LOCUS       DAMKNB010000001       114941 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.001, whole genome shotgun sequence.
ACCESSION   DAMKNB010000001 DAMKNB010000000
VERSION     DAMKNB010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 114941)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 114941)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..114941
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.001"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            complement(101..1180)
                     /locus_tag="PC494_000001"
     CDS             complement(101..1180)
                     /locus_tag="PC494_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HDF3910535.1"
                     /translation="MSRRKKGISLVILVAIISSILSSFLTIILVKDNLVSKSTGSSTP
                     IVVNDDGKSQNIYQAVAEKATPSVVGITTTSVDTSNMFAIPTETQGVGTGIIVDSNGY
                     ILTNSHVISDGQATSVNVLFNDGSTTSGKVVWFDQQLDLAIVKVDKTGLTPAEFADSD
                     KVKVGDISIAIGNPLGLDFQKTVTQGIISGLDRTIQTEKTNMTGLLQTDASINAGNSG
                     GPLLNQKGQVIGINTAKASQAEGLGFAIPINTAKSIVEEVIKNGKYEKVTLGIKGTDV
                     SNYEAATGTKLSTDKGVYVAEVISGSSAEKAGVKVGDIITKVGDTDITGMNDLNKKLY
                     TFSKGASTKITVNRGGKAVTINVNF"
     gene            complement(1336..2685)
                     /locus_tag="PC494_000002"
     CDS             complement(1336..2685)
                     /locus_tag="PC494_000002"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HDF3910536.1"
                     /translation="MGKINFDYSKATEFFCQNEIDVMQPYVDVAHDMLHNKTGLGNTF
                     LGWIDLPKNYDKEEFDRIKKSAEKIKSDSDVLLVIGIGGSYLGSRAAIDMVSHSFRNG
                     LKKEQRKAPEVYFVGHNISSTYIMDLLDIIEGKDISVNVISKSGTTTEPALAFRIFKD
                     YLEKKYGKEEARKRIYATTDASKGALRQLATEEGYETFVIPDDVGGRFSVLTAVGLLP
                     IAAAGLDIDAMMKGANDAREAFQNPDLKSNDSYRYAVARTILHRKGKDVELLVNYEPQ
                     LHYVSEWWKQLYGESEGKENKGLFPASVDFSTDLHSMGQYIQDGKRLLFETVLNVENC
                     KRNITISSEEVDLDGLNYLAGKTVDFVNHKAFEGTLLAHTDGKVPNLVINIPQLDEYN
                     FGYLVYFFEKACGISGYLLGVNPFDQPGVEAYKKNMFALLGKPGYEKEKEELEKRLK"
     gene            complement(2950..4578)
                     /locus_tag="PC494_000003"
     CDS             complement(2950..4578)
                     /locus_tag="PC494_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
                     /protein_id="HDF3910537.1"
                     /translation="MNIIISLMGGLGLFLYGMNLMGEGLQKSAGTKLKKIIKLLTSNL
                     FMGVLVGTGVTAVIQSSSATTVMVVGFVNAGIMTLKQAIGVIMGANIGTTVTAQLVSF
                     DLTGMAPVALGVGIILYLFGNKPRIKNIAEILIGFGILFTGMDFMKMAVEPLRDYQGF
                     TDLLVTFGRYPLLGLLLGFGITAIIQSSSASMGMLVALAAEGLVPLSAALPILYGQNI
                     GTCVTSLLSSIGANKNARRAAMMHLIFNVLGTVIFLIFLNKPVVSMVTSWDPSNVARQ
                     IANTHTLFNIISVLILLPFTNLIIKLAIKLVPDRAGDIDEDETKTIKYIDDRMIETPS
                     IALANTIKEALRMGEKAKESLNASMEALVEHSTEKIDKTYRRERLINDLQKAILNYLL
                     KLSKAPLGDDSREVVDTLFNTVNDIERIGDHAKNIAELSQVAIDSNISFSEEGQSELD
                     VMYNRVVSAYTYALESMRTDNVDLACKVIKIEEQVDIMEKSCRANHMYRLNNNLCSIE
                     NGVIYLDVISNLERISDHAVNIAQQVIAKRLGND"
     gene            complement(4702..6306)
                     /locus_tag="PC494_000004"
     CDS             complement(4702..6306)
                     /locus_tag="PC494_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3910538.1"
                     /translation="MLRVSNVKLGIDKDISLLKDVILKKLKIKEKNLVKYSIYKESID
                     ARKKGKMEFVYSVDVEVKDENKILNSKIKDVTKIKEIRYVNVPVGDKKLKNNPLVIGS
                     GPAGLFAGLLLAQMGYEPIILERGLDVDSRTKDISDFWTTRKLKNNSNVQFGEGGAGT
                     FSDGKLTTRIKDIRCRKVLEELVQFGAPDEILYSHKPHVGTDILKNVVKNIRNEIISL
                     GGQVRFNSKVTDIVVSNDSIQSVIINDTEKIDTDTIILAVGHSARDTYEMLYSRGIKI
                     VQKPFAIGARVEHPQDLINKAQYKDFYNHPRLGAADYRLIEHVSNGRTAYTFCMCPGG
                     SVIASASNDFEIVTNGMSEHARDKINANSAFLVNVTPEDFKSDNSLAGVHFQQKYEKL
                     AFELGGKNYNAPVQLVGDFINNKTSLNLGSVEPSYRPGYTLTNLSECLPSFVTETMRE
                     AFISLDKKLNGFAMYDAVLTGVETRSSSPIRIVRDENTLESVSIKNLYPCGEGAGYAG
                     GIVTAAVDGIKCAEKIIQKYTNNTKI"
     gene            complement(6354..6671)
                     /locus_tag="PC494_000005"
     CDS             complement(6354..6671)
                     /locus_tag="PC494_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3910539.1"
                     /translation="MDYIGIENITPYENTYEFSVYEYDDEITLGSEKLYVCELRVVLI
                     KVNSLYVERLHKSVEAMVLVKNLKKDLDKTLVVNKIKNFVLDEIWVENLVKENIEVIF
                     VES"
     gene            complement(6676..7041)
                     /locus_tag="PC494_000006"
     CDS             complement(6676..7041)
                     /locus_tag="PC494_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3910540.1"
                     /translation="MSLSLGNAIAVSTNFIKSNPAVPVYNGEEIYAVIYHIEIGYNNG
                     VSPDTKQYIIIDYKEFDLSMDKKNELINIAKEYCKSKGIVENENLEINLLDNEEAENF
                     LEKVFNNMKVIRGLITKKG"
     gene            complement(7122..8159)
                     /locus_tag="PC494_000007"
     CDS             complement(7122..8159)
                     /locus_tag="PC494_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SEC-C domain-containing protein"
                     /protein_id="HDF3910541.1"
                     /translation="MLGRNELCPCGSGKKYKKCCLNKDIVSERACRKTELSQKQYTDL
                     YSKLYDYSRQDKFKEECEKAKEMFYIMQNDSVNEKFERFFNTYLIQDHIMENKKVMTV
                     GFLEENGTNLSQSEVSILKSMFESYVSIYEVKEVSAGKIVLKDCLSGNELCTEDVKLL
                     RSFKIGSCMIARIVDIEGTNILIDITISISNEVKDIILKDIMNLFNQYQDVYKDMKSF
                     LIYHTHILYKYIQQLLDPSIAEYLKRERDKNDTKVNSENELAEEECKVLDTLKENVEK
                     ENIDACIEFWNEYKKNHENIKGAENGWAAAVEYYVKKEAGQPITQVQISKKYDISSST
                     LGKRYKDLKIS"
     gene            complement(8412..8996)
                     /locus_tag="PC494_000008"
     CDS             complement(8412..8996)
                     /locus_tag="PC494_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3910542.1"
                     /translation="MRLNNREKNLLKILLILVIILASDIAVSYLEENLTSLKNEKQNI
                     INKINNQDNYQIKDNKHIDDKYIESVESNKNEELKNNFNNSFLDKKTNKDIVLLVENE
                     LRDIVNVEYINQESSLDNHNKKQVNLEIKVNGELANVLKLEGVMKKLRLNNKLEKIEI
                     NKLKVNNFDVQNIPNEYKQEKDNIVECKMTVRVI"
     gene            complement(9011..9454)
                     /locus_tag="PC494_000009"
     CDS             complement(9011..9454)
                     /locus_tag="PC494_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3910543.1"
                     /translation="MKVDKTINFLNGFKKTKPCNKIYKIIIVLILTCILFKSFMYVKS
                     INELEDYISQNKLVDKSKNTLPTTDKTREKFSKIKLNEIKKIYETIGINSITKISIDK
                     NKLEMEGVCSDLDVLNNLRKIKYIKYYYIDSIVRDGEYYRFRIKS"
     gene            complement(9455..10327)
                     /locus_tag="PC494_000010"
     CDS             complement(9455..10327)
                     /locus_tag="PC494_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pilus assembly protein PilM"
                     /protein_id="HDF3910544.1"
                     /translation="MAIIKKILNLEINDDYIRLVFLRKGHKKVFIDKSIIKEINFDIK
                     NDSNSIEKIKYIEDVVRFVKEEIGKSKILYKNLYFNIQIQDIVIRNVEVLNTKKKRDI
                     LSMIEFEITQYIPININNYSIKYKVINSKNDKLNIQVILFPKSIIQLIKNISENLNMN
                     PKTININFDILQKLINLNLIENFSEEGVFIECKKSQLIINITKDKKIRETYLLSKEGK
                     SYEFIKRLLRDFKYVYYYGIENCFIEEYFKYTDKSIEVNPLRLKDKVKVENNFDADLE
                     DNRINYISNIGMII"
     gene            complement(10380..10739)
                     /locus_tag="PC494_000011"
     CDS             complement(10380..10739)
                     /locus_tag="PC494_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HDF3910545.1"
                     /translation="MINLINKKRKGFTLVEMIVVVTILGVISSIALVKYSKVQESAKL
                     NADYTNAANIVTAASMAINDDEKTIDSLSVETLKEKGYLNTVPVPQSTSGKFELVIND
                     SGTDISVNINSKQFYPK"
     gene            complement(10793..11878)
                     /locus_tag="PC494_000012"
     CDS             complement(10793..11878)
                     /locus_tag="PC494_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system F family protein"
                     /protein_id="HDF3910546.1"
                     /translation="MRLSKNIFYNLEKFYLVLNRISDKEIRVICKEIGILLESGCEIT
                     KIFEIIESQSSKKAKNLLSIVSNHIQKGNSIAESFQITGIFSKFFISMIKAGETSGNL
                     DIIMSDLSNYYDKEYKLKMKIITISIYPIILIILSILSMLFIFVFVIPNFQVVFTNNG
                     IEPPLITRVLMGISTVVTNNLAYIIFSFILFSIGSIYFFITNDNIKKLINSLKFKIPF
                     IKKINQLVATTRFSRALSVLISSGIQIVEAIDMSASVIDNEFIYERLKISNNYIKKGN
                     SIGKSLNLANVFPKLFISMANIGEESGKLDKSLNVINKFYENELNNKIEQIMKFIEPM
                     LIVFMGLIIGTFILAMVVPMFDAITNF"
     gene            complement(12049..13428)
                     /locus_tag="PC494_000013"
     CDS             complement(12049..13428)
                     /locus_tag="PC494_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II/IV secretion system protein"
                     /protein_id="HDF3910547.1"
                     /translation="MIKIILEESSLPMLIPEKLAKKYNVFPVEFQDDNLVVEIEDEDI
                     YALQDLRLATGKEIILKKEKKELISEKIEKYYNSFELDEDYAKKLFENLLEKAIKENA
                     SDIHIEPFKEHLIVRMRVDGELKEVSKFLVDVYPSLSTVIKLKASMDITEKRLPQDGR
                     VDIKLGGNLIDIRVSSIPTVYGEKIVLRILNRDTFLKDKLELGFSEEAIKSINRIINK
                     RAGILLVTGPTGSGKTTTVYSLLNDLKGINKNIMTIENPVEYKMDGISQIQVNSKVGL
                     SFDVGLRAILRQDPDIIMVGEIRDAETAKIAVRAAITGHLVISTLHTNDAVSSIARLL
                     EMQIPPYLLNASLIGVISQKLVRKVCNHCSHEIMIKDNFSGDVNTKVAVGCEKCNDKG
                     YFGRTAIYEILEINDDIKTCIRNMEDSSTIKDVAQNNGMITFEDSCKRLINEKITTLE
                     ECLVVNEMI"
     gene            complement(13421..14101)
                     /locus_tag="PC494_000014"
     CDS             complement(13421..14101)
                     /locus_tag="PC494_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF881 domain-containing protein"
                     /protein_id="HDF3910548.1"
                     /translation="MKKQYVFIILTSTILGILVGTIFRDYSNEETVYTSKDKSIRKEI
                     KMTRKSIKELTKEKDKLDKEINSMKQNQKNSEEISEIETLRDSLSYSDVKGSGIILSI
                     DAIDEKTGNIANSIDYNKILVKVINELKVNGGKYIEINGQRINQYSEVVLAGSHININ
                     GVPVAQPYEIKCIGDKEKLSNYVDKGSKYLDSIQTNYPMKISIKTEENISMKKMNIPN
                     KLKYIKGD"
     gene            complement(14493..15572)
                     /locus_tag="PC494_000015"
     CDS             complement(14493..15572)
                     /locus_tag="PC494_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HDF3910549.1"
                     /translation="MEGKVKKAFPGGNTSQGSYSFFDYIIPENVKRVFCLKGGPGVGK
                     SSLMKKIYKEFLHRGYDIDLYHCPSDPSSLDGLVIKKLGVVLMDATAPHTMDPKLPGA
                     LDEIINLGDYWNTEELEKNKQEISVYDKDISNSFKRAFKFLKSAEPIFRDIEEKYSDC
                     MDYGKVNLVTEEFIKRLFDGVKSTGNLKREKHLFGSAITPVGCLDYTENILKDVKKVY
                     YLDGEIGTGKTTLLNKVYKKAIEKGLNVEVYHYPLIPEKIETVLLTDLDIGITISTTF
                     KEEDTIDLNQFLNREKLLKYEEDIKFDEKVLDDLICWAVLNLKRAKSKHDIIESYYSP
                     NMRFDEVGKLRDKLIKRILKYEENL"
     regulatory      15860..15975
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            16150..17520
                     /locus_tag="PC494_000016"
     CDS             16150..17520
                     /locus_tag="PC494_000016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDF3910550.1"
                     /translation="MKQKWIVLIIICIGVFMSTLDGSILNIANPTIAADFKINMSQIQ
                     WVVTAYMLVVTATMLFFGKLGDKVGSNRLYTLGFFIFTIGSFLCSMSNNLSTLISSRI
                     FQAVGASILMATGLGIVSNAFPANEKGKAIGITGAVVGIGNMSGPVIGGIILEHFGWP
                     SIFIINIPIGIIAVFLGIKFLPKPVLDEQNKSFDIPGLLLFASCTTLILLAMNEKGNT
                     RLYLGITALIIFLLLALREVKFEQSFIDLPLFKNRNFTVGNIIGVACYFPQMAVSFLL
                     PFYLEQLKNLSPMMAGYVMTVHPLIMVLIAPIAGSLSDKHGAKNILTASFSFMTISLV
                     GMALLKADSPLYLLIVCLVIFGLGLGAFSSPNNSSILADVPPQKQGYGGSFLATIRNL
                     SFALGTAFFSSFFAQSLTYNQKFKSHTSAYVIASNQSYWIAASVCFIGLILTVFFMRK
                     TDKSIS"
     gene            complement(17785..18396)
                     /locus_tag="PC494_000017"
     CDS             complement(17785..18396)
                     /locus_tag="PC494_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HDF3910551.1"
                     /translation="MKIRSSEITMSAVNKSQYPAEGIPEIALAGRSNVGKSSIINTLL
                     NRRNFARTSQTPGKTRTINFYLINNEFYFVDLPGYGYAKIAKSEKEKWGGIMERYLES
                     RQELCSIFLLVDIRHEPTADDKLMYEWIKHFGYNCVVIATKADKISRGQYQKHISIIR
                     KKLQMESSEKVIPVSSLKKTGVEELWEEIVNQYNQHGYEITVD"
     gene            complement(18386..20749)
                     /gene="lon"
                     /locus_tag="PC494_000018"
     CDS             complement(18386..20749)
                     /gene="lon"
                     /locus_tag="PC494_000018"
                     /EC_number="3.4.21.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endopeptidase La"
                     /protein_id="HDF3910552.1"
                     /translation="MEQNYTKIDHELPLIPLRGLAIFPYMILNFDIGREISLKALDQA
                     MMDEELIFLTSQKEAEVDEPGEEDFYHVGTICKVKQMIKLPGDTVRVLVEGVSRGRVK
                     KIEQEDGYFRAVIEEIVFDSDNLDSETEVEIEAFVRNVFDAFEEYINIGNRVSPEILI
                     SLADIEDVDRFIDTIAANIYLKSSQKQEILEEFDIRKRLELIYSILLEEIDILKIEKK
                     ITLRVKKQMNKVQKEYYLREQLKAIQKELGEEEDINSEADEYREKLKKIKAPKTTKEK
                     IEKEIDKFSKISSMSPDVSVSRNYLDTIFSLPWNKETKDKLDITKAKDILDEDHYGLE
                     KVKERILEYLAIRTLAKSLKGPIICLVGPPGTGKTSIVKSIARALNRKFVRISLGGVR
                     DEAEIRGHRRTYVGSIPGRIINGVKEAQTKNPVFLFDEIDKMAADYKGDPASAMLEVL
                     DPEQNKDFVDHYLEIPFDLSKILFVTTANSLGNIPRPLLDRMEVIEVSGYIEEEKLNI
                     AKKYLLPKQIKEHALKENFIKIDDETLRSIINHYTREAGVRTLERTIGKICRKVAKKY
                     VEDPTLEEVVINKSDLETYLGKDMFKYQLAEVNPQIGLVNGLAWTEVGGVTLEVEVNV
                     LKGKGEIVLTGKLGDVMKESAKTGISYIRSIVDKFDIDPEFYKTNDIHIHIPEGAVPK
                     DGPSAGITMALAVISALTKRPVPGNIAMTGEITLRGRVLAVGGVKEKLLAAHRAGITK
                     VLIPKECEADLDEIPENVKEKMEFVLVEHMDEVLEQALLKSGENNEN"
     gene            20929..21441
                     /locus_tag="PC494_000019"
     CDS             20929..21441
                     /locus_tag="PC494_000019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromate transporter"
                     /protein_id="HDF3910553.1"
                     /translation="MLKLFLTFLKIGAFTFGGGYAMVPLIQDELVNKQKLLEQEEFID
                     YLSIAQSYPGVLAVNISVLLGYKLYGIPGVLICTLGSALPSFCIVLVLSYLYFKNSSS
                     KILDGFFKGVAPVVIALILYSFTSMFKKLPKSKTNILLLIIAVLSVGVFNISPIYLII
                     GGGVYSLCQK"
     gene            21429..21956
                     /locus_tag="PC494_000020"
     CDS             21429..21956
                     /locus_tag="PC494_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromate transporter"
                     /protein_id="HDF3910554.1"
                     /translation="MSEIILLFLIFLKIGAFSFGGGYAMLPFIQQEFISKYHFITNQE
                     FLDLLAISQSTPGPVAINSATFVGFKTAGFFGSLAATIGVTIFALIGLTIISKLFSKF
                     KNNKKVENLLTVLRPITLGFILSAAFSSAKEVNWDLYGIIAFIASFYLLYKGKIGSIA
                     IVFVFGILGILLTFL"
     gene            complement(22027..23277)
                     /gene="clpX"
                     /locus_tag="PC494_000021"
     CDS             complement(22027..23277)
                     /gene="clpX"
                     /locus_tag="PC494_000021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HDF3910555.1"
                     /translation="MSKYEEKRQLKCSFCGKNQDQVRRLIAGPNVYICDECVELCDEI
                     IQEEIEDTIDEDTTSLPKPKEMMEILNDYVIGQEKAKKALSVAVYNHYKRIYSKKSSS
                     KDIEIQKSNILLLGPTGSGKTLLAQTLARTLNVPFAMADATSLTEAGYVGEDVENILL
                     KLIQAADFDIEKAERGIIYIDEIDKIARKSENPSITRDVSGEGVQQALLKILEGTVAN
                     VPPQGGRKHPHQEFLKIDTTNVLFILGGAFDGLEKIIQKRGGDKTLGFGAKIESKKEL
                     DLGKLYEKVLPEDLLKYGIIPEFIGRIPVLATLELLDEDALMQILQEPKNALVKQYKK
                     LLELDDVELEFEEGALRAIAKKAIERNTGARGLRSIVESVMMETMFEVPSRDNIKKVI
                     VTEKSVNEDSVNPIIVLKDQEESA"
     gene            complement(23296..23880)
                     /gene="clpP"
                     /locus_tag="PC494_000022"
     CDS             complement(23296..23880)
                     /gene="clpP"
                     /locus_tag="PC494_000022"
                     /EC_number="3.4.21.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp endopeptidase proteolytic
                     subunit ClpP"
                     /protein_id="HDF3910556.1"
                     /translation="MALVPVVVEQTGRGERSYDIFSRLLKDRIIFLGDQVNDATAGLI
                     VAQLLFLEAEDPDKDIHLYINSPGGSITSGMAIYDTMQYIKPDVSTICIGMAASMGAF
                     LLAAGAKGKRLALPNSEIMIHQPLGGAQGQATDIEIHAKRILKIKETLNEILSERTGQ
                     PLEKIKMDTERDNFMSALEAKEYGLIDEVFTKRP"
     gene            complement(24030..25316)
                     /locus_tag="PC494_000023"
     CDS             complement(24030..25316)
                     /locus_tag="PC494_000023"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HDF3910557.1"
                     /translation="MKAELIKKEGNKVTLKITVDNNKFEAAVNKAYNKSRNKYNIPGF
                     RKGKAPRIVIETQYGKGIFYNDAIEILFPEVYPEAIKELDIDPIDNPDLDIEEISKDN
                     GLVMVLNVEVKPEFELGNYKGIEIAKVENTVSDENVDAKLQEMVEKNARLVSVEDKAL
                     EDGDTAIIDFEGFENGVAFDGGKGENYNLVIGSNTFIPGFEEQLVGKKAGEEVEVNVT
                     FPEEYHSQDLAGKPVVFNVKINDVKVKELSALDDEFAKDTSEFDSLDELKADVRAKLE
                     EEAKNRADAETRNSVVEKVAENTEIEIPEVMIQHQIDNMLNELNYQLQYQGFGLQQLL
                     EMTGRTMEELREERKEDAKKLVKSSLVLEAITKAEGIEATEEEFKAELEKMASAYNME
                     VEKIEASLRDADKEDIKGQIKIRKTIDLLVDNATIA"
     gene            complement(25510..25980)
                     /locus_tag="PC494_000024"
     CDS             complement(25510..25980)
                     /locus_tag="PC494_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HDF3910558.1"
                     /translation="MKIGIVSDTHMMIKNMEKTIPYLKECDLIIHAGDNFTDSRYIHS
                     MTNVGIIAVKGNCDFDAVEEEVVFEVANKTIFLCHGDKYGVKYGTNMLEKKATEVDAD
                     IVIFGHTHTPFREIKDGVLYINPGSTSLPRGVSYKSFVIMDIEEDDIKIEEIRI"
     gene            complement(25980..27329)
                     /gene="rph"
                     /locus_tag="PC494_000025"
     CDS             complement(25980..27329)
                     /gene="rph"
                     /locus_tag="PC494_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease PH"
                     /protein_id="HDF3910559.1"
                     /translation="MTRSYDRSNEQIRPVKITRDYTKYAEGSVLIEMGETKVICTASV
                     EEKVPPFLRNSGTGWINAEYSMLPRATQQRKIRDASRGKIDGRTQEIQRLIGRAIRSV
                     VDLNKLGERTIWVDCDVIQADGGTRTASITGAFVAVAEAIYKLYKAKTIKEMPITNFV
                     SAISVGIVNGIHMLDLCYEEDSKAQVDMNIIMTDKCEFVEVQGTGEEKPFSRADLNLL
                     LELGEKGNKELIRLQREALGEISDEILGMDYGNEVVIATNNAHKLEEIGEILKDFEYK
                     VYSLKDVDLAGIEIVEDGKTFEHNALIKARTIAKKTKLIAISDDSGLEVDALGKKPGV
                     YSARYAGEHATDEENRKKLLKAMQNIPMSKRNARFVSAIAVVFPDGKEFVVRGICEGM
                     IGFEEKGKNGFGYDSLFIVKGYDKTFGEIPSVIKNSISHRANALKLMKQEFIKRVVK"
     gene            complement(27489..29513)
                     /gene="ligA"
                     /locus_tag="PC494_000026"
     CDS             complement(27489..29513)
                     /gene="ligA"
                     /locus_tag="PC494_000026"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HDF3910560.1"
                     /translation="MSVKDEINKLIETINYHNERYYNQDSPEISDYEYDKLMKELISL
                     EEEHPELKRIDSPTNRVGGKPLDKFNQIVHKTPMLSLSNAFSEQDLRDFDKRVQEYVG
                     ENVEYVVEFKIDGLSVGLTYNNGEFEKGATRGDGVVGEDISQNLMTVKSIPLKINDKK
                     ELIVRGEVYISKDNFRKVNEQQEEQEQPLFANPRNLAAGSLRQLDPKLTAKRPLDIFV
                     FNMENIEEYDLESHSESLEYLEKLGFSVSQSYKVCKSIDEVIEHIEYWTDNRGNLDYE
                     IDGMVIKVNNIKQRDEMGYTAKSPRWAIAYKFPAEKKKTKIVDIIVEVGRTGTITPSA
                     ILEPVRLAGTTVSRATLHNEDYIREKDIKINDTVLVQKAGDIIPQVLEVIKEERTGDE
                     IDFKMPEKCPVCSEPTIRLEGEAAVKCINMSCPAQIRRGIIHFVSRDAMNIDGLGESI
                     ITLLLNEKIIQDVSDLYYIKKEDVVDLERMGEKSADNLINSIEKSKENDLWRLINGLG
                     IKFIGVKAAKILAYNFKDLDEVISATSEQLEELEEFGSIMANSVVEFFKEDKNMNVIN
                     KLKNVGVNTKSLDNTGEKVEKIFEGMKIVLTGTLPTLKRNDAKDMIEKRGGKATSSVS
                     KSTTFVLAGEEAGSKLTKANDLGIKVIDEERFLELLKLSSKDEVKAVLES"
     gene            complement(29699..30637)
                     /locus_tag="PC494_000027"
     CDS             complement(29699..30637)
                     /locus_tag="PC494_000027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate dehydrogenase"
                     /protein_id="HDF3910561.1"
                     /translation="MKVLFTINYGKEKFDKIRELGYDVIHYSEDSIENNEDVNTADVL
                     VTYNPFERLDISKMKNLQYIQTTSVGIDQLPKEEVLKRNIKIANNRGGYSVPIGESIV
                     LYILEIYKNSAKFFKQQQNKEWKMDFSVSELYGQRVGFLGTGTISSEAAKRLKAFGVE
                     IWGVNTDGSSKKYFDKCFATEDMNIVFEECDIVVVAMPSTKSTDGIVNKDMFKLMKDG
                     SVFINVGRGNTVNQKDLEECVEKFRGVALDVFESEPLNKDNKLWECENVIVTPHNSWV
                     SDKNKERTFNMVYNNLKHYIMENKPVDNVVDISRGY"
     gene            complement(30739..31161)
                     /locus_tag="PC494_000028"
     CDS             complement(30739..31161)
                     /locus_tag="PC494_000028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3783 domain-containing protein"
                     /protein_id="HDF3910562.1"
                     /translation="MSFEKINNNNLDKIHNRKCIMLVNFNKKELSLIKNVSNFAGIRD
                     HIILSDKNGENIIRDILDGNISNECENGIKSKSVIFNNTPSTQVNAFLEGLKKVRINR
                     PFTAMVTETSIDWTLNNLIENLVQERNAMSLGKTIEHK"
     gene            31349..32632
                     /locus_tag="PC494_000029"
     CDS             31349..32632
                     /locus_tag="PC494_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugated bile salt MFS transporter"
                     /protein_id="HDF3910563.1"
                     /translation="MNTLLNNKFSIKNFSNAWVIVLGCMLIQAVPFSIVASIQPQFIS
                     YVVEGEGFSLASFSLIFTIGTIASAIASPFIGVLFSKVNIKILYLLGCIISSIAFATF
                     SICTELWQFYTVSCIVQIGATIISAIGIPVLISAWFDEESKGKALGFAFAGGSIGSIF
                     LQPLAVRLLATQGYSRSYLIFGIIALIVGIPVILFILRMPKDINEKVKSKGKKEKASD
                     TISPSVWGYTLKEAKKIKYFWIMTIGFIFVGIYVSSLSVQYPTYLRNYLNPILIGTVG
                     STFALFALIGNLFGGLLFDKFGQTKPLIISFVLVLIATLSLLLVDKSSTFAFVFAILK
                     GLSVFAYMIGPAYLTGSFFGQKEFGSIYGIVQLIFAVGFALGSTLFGLLVDNFGYRFS
                     WSIIILSVIIAYTLLIITSIGMKNLNKERLDKLMQ"
     gene            complement(32710..33225)
                     /locus_tag="PC494_000030"
     CDS             complement(32710..33225)
                     /locus_tag="PC494_000030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HDF3910564.1"
                     /translation="MNYFVIADPDKCIGCRTCMIGCVVAHSDEDIFYQNPDEINFNPK
                     LSVIKTKEVSAPIQCRHCEDAPCAKACPNGGIVRVGNTIKINEENCIGCKTCMLACPI
                     GAIDIVTLKDVDEGKLCFRERMTANKCDFCIESPEGPACVNVCPTKAFTIVKDEDIDS
                     KVKNKRKLAIL"
     gene            complement(33225..34601)
                     /locus_tag="PC494_000031"
     CDS             complement(33225..34601)
                     /locus_tag="PC494_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron hydrogenase small subunit"
                     /protein_id="HDF3910565.1"
                     /translation="MIINIDKDLCTGCRECSKVCPVNAIEGEEGKPQEINLDRCVMCG
                     QCVQTCKSYASVIDEGFEFLQEKKQEREIPESINEPIFAAYNVCDIDKVKKALSDPNV
                     FTMVQCAPAVRVALGEDFGYYLGYLGAGKMAAALRALNFDRVYDTNFAADLTIMEEGS
                     ELIKRVTEGGTLPMFTSCCPAWVKFMEKNYPKLTNHLSSCKSPQQMGGAIFKTYGAEI
                     NNVDASKIFSVSIMPCTCKKYECDREEMDSSGYRDVDVVLTTRELAYLIKDMGIDFKN
                     LREEKFDSPLGSYSGAGTIFGVTGGVMEAAIRTGYELITGESIPDVEVKQVRGENGFR
                     KSTIKIGDLDLRVGVVSGLKNVIPVLEDLEKGKLDVDFIEVMTCPVGCVSGGGQPKIL
                     LEEYKELAYENRTKATYVHDEHLAIRKSHENPDIKKLYDEYLVEPLGEKSHHLLHTTY
                     CIGKEVAK"
     gene            complement(34626..35177)
                     /locus_tag="PC494_000032"
     CDS             complement(34626..35177)
                     /locus_tag="PC494_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HDF3910566.1"
                     /translation="MKNKIGSFVIADPNKCTGCRACEVACFTMHNQHNNVGYTVGTVD
                     IPVIPRLYLVKGDNFCMPIQCRHCEDAPCLNSCPQKAIVKENNIMSVNEEKCIGCKTC
                     LLACPFGAIDLLPQYEDGKEVEQVILDENKKIAYKCDLCKDNEKIACISACPQEALKL
                     VTPIDDKKAKNRQAALSLLLTNK"
     gene            complement(35235..35450)
                     /locus_tag="PC494_000033"
     CDS             complement(35235..35450)
                     /locus_tag="PC494_000033"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3910567.1"
                     /translation="MQIHRELSKSENEYMCTKKEKQRYSKCEICGVLIDDTDKVYNNT
                     YNLCKKCKRNISTEKIVKYINIYDESK"
     gene            complement(35419..36252)
                     /gene="fdhD"
                     /locus_tag="PC494_000034"
     CDS             complement(35419..36252)
                     /gene="fdhD"
                     /locus_tag="PC494_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate dehydrogenase accessory
                     sulfurtransferase FdhD"
                     /protein_id="HDF3910568.1"
                     /translation="MNNIYSKTKLQENSKDKVFENSYSLVDYKYLNSFNVEVSKINEH
                     EVSIDNEEIIAEYPLSFILNDKYVNTFLCTPYNLEELIVGFLKTKGYIENKKSLLKFE
                     INESERFAKVTIQEKQKNQDEQIIFLNSLDYITCAPVKSNIKINYDTIYSIMDKNLNS
                     SELFKNTGGVHSVSVFNFDKKIVTCEDVARHNAMDKAIGFCVLNDITLKDKIVAVSGR
                     ISLEMILKAAMTQIPIVVSKSAPTNLSIELSKKLNITLIGFVRGRRMNIYANPQRVIK
                     K"
     gene            complement(36301..38445)
                     /gene="fdhF"
                     /locus_tag="PC494_000035"
     CDS             complement(36301..38445)
                     /gene="fdhF"
                     /locus_tag="PC494_000035"
                     /EC_number="1.17.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_except=(pos:complement(38029..38031),aa:Sec)
                     /transl_table=11
                     /product="formate dehydrogenase subunit alpha"
                     /protein_id="HDF3910569.1"
                     /translation="MEKKILTVCPYCGAGCQLYLVVKDNKILRAEPANGRTNQESLCL
                     KGRYGWDFLNDPKILTPRLKKPMIRKQGVLEEVEWDEAINYTASRLNEIKEKYGPDSI
                     MGTGSARGPGNEANYIMQKFMRATIGTNNVDHCARVUHAPSVAGLAYSLGSGAMSNSI
                     PEIENADVLFIFGYNGADSHPIVANRIVKAKKNGAKLIVTDPRVTESARIADIHLPIK
                     GGTNMVLVNAFGNVLIEEGLYNKEFVQNHTQGFDEYKEIVKPYTAKYAEKITGIPEEL
                     IRKAMREYAKGKKAMILYGMGVCQFGQAVDVVKGLASIALLTGNFGRESVGIGPVRGQ
                     NNVQGACDMGALPNVYPGYQNVTDDKIREKFEKAWGVKLSPNNGYSLTQVPDLVLKEK
                     KLKAYYIFGEDPVQSDPDASEVREALDELEFVIVQDIFMNKTALHADVILPATSWGEH
                     EGVYTCADRGFQLMRKAIEPQGDVKPDWQIISEISTAMGYPMNYKNTKEIWDELRQLC
                     PSFLGATYEKIETQGCVQWPCKSESMEDKGTMYLYEGQKFSTPNGKGNLFAAEWRPPM
                     EVEDDEYPFSLCTVREVGHYSVRTMTGNCRTLSSLEDEPGRVQINSNDAEKLGIEDDE
                     LVRISSRRGSVITRATVTDRVKEGATYMTYQWWVGACNELTIANLDPISKTPEYKYCA
                     VKLEKLEDQELAEKCVREEYQSLKDKMTATNI"
     gene            complement(38696..39754)
                     /locus_tag="PC494_000036"
     CDS             complement(38696..39754)
                     /locus_tag="PC494_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flippase-like domain-containing protein"
                     /protein_id="HDF3910570.1"
                     /translation="MDRLKNIRKSLLQYTFLFLLIGITIYLVFKTLDIKMLSNVMVMV
                     DKKFLFIGALAIMCHIMLEGVVMKIIIESTHKVNIRFIGFKLAIMGFYYNLITPFASG
                     SQPVQIYVLKKCKMPLSKASAVVTNKSIIFQIVVTFYCTILVLMNFAMLEKQMKMIMP
                     LVFLGIAINSFVLIMIILVILNPKKIKYFMRITIKHLSKIKFLKFLDNKIESIESFID
                     DYSKAINFFAKNKKVLISTIIVTFIQLSAYFSVSFWIYKAFNLQGYSYIYILTLQAFL
                     YMAISPIPTPGNVGANELAFFTIFKSVFPQPLMGYAVFLYGGFMYYLILIGSGIFTVI
                     THYRMKNRIGRNIVLSEN"
     gene            complement(39965..40624)
                     /gene="cprR"
                     /locus_tag="PC494_000037"
     CDS             complement(39965..40624)
                     /gene="cprR"
                     /locus_tag="PC494_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator CprR"
                     /protein_id="HDF3910571.1"
                     /translation="MSKILVVDDELDMLKLIENVLKRDGHEVKVISDVEKAMNMDFNY
                     FNLIILDVMMPKMDGFEVCKTIRNKVDCPILFLTAKNMESDIMYGLGIGADDYITKPF
                     GVGELRARITAHLRRESREKKNLLTISNVQFNFLGKEVSIDGKKINFTKSEYLICEFL
                     AKNKGQVFSKERIYESVYGFDGESDISTITEHIKNIRSKLKQYDIYTIETVWGIGYKW
                     V"
     gene            40935..41564
                     /locus_tag="PC494_000038"
     CDS             40935..41564
                     /locus_tag="PC494_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3786 domain-containing protein"
                     /protein_id="HDF3910572.1"
                     /translation="MDEKITKNNYNVPFDYVRKKLKELDPHTISNLSNIPFNNDLNRF
                     TLNFFDRQYIIDYPSGEVWNSNGSLCNNFELKILIVRYLINAKGIPRTNKYVTFKEIP
                     GGNVYYPNFLNRTLYRLSEVFTSQIDKYKLVMEKIGAEKVNMGDLAYRFTYMGNTSMV
                     FILWFGDDEFPPNSNILFDSNIVYYFNAEDLAVVPDTAINAILNKINQL"
     gene            41632..42465
                     /locus_tag="PC494_000039"
     CDS             41632..42465
                     /locus_tag="PC494_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prenyltransferase"
                     /protein_id="HDF3910573.1"
                     /translation="MNVENQSLSDIEIILSHRYDNGADYWTTPDKRLIKGSPFSTLDS
                     VLYLLELGVNPDDTLLKECADLIFSTWREDGRFKLYPNGGIYPCHTANAANVLCHMGY
                     ASDIKMQKTFQHFLDTQYTDGGWRCNKFSFGRGPETEYSNPLPTLNILNAFRFSNYLN
                     KESKLDKAVDFLLDHWTIKKPIGPCHYGIGTLFMQVEYPFRNYNLFLYVYVLSFYNRA
                     KKDNRFLEALKILESKMIGNKIVVERVVPKLSKLSFCKKGESSEIATTHYYEILKNLE
                     K"
     gene            complement(42561..43349)
                     /locus_tag="PC494_000040"
     CDS             complement(42561..43349)
                     /locus_tag="PC494_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3910574.1"
                     /translation="MCILELIKFELKKIELKHVLIFVIISILCIFITGILDYNELIFY
                     NDVPIMDTYSIAGWLGIIKISDVFIPIMSAITIIYVFSKDYSGNINEILTLYNKKKYN
                     QFIVFRWCVILAIYTVLLLISITIVYTFTSVKGFNIDKIDFVYSVKPIDVFLKTFPTL
                     LWYTTFPLMILTLTKNRFTTIAILITYTFADIFFILHMYPFVSMINVNGFYIQKMFYM
                     PNNIDVRFNELKNYFFINRGSLVVISIIIVFYIARKSTVLKKSK"
     gene            complement(43350..44222)
                     /locus_tag="PC494_000041"
     CDS             complement(43350..44222)
                     /locus_tag="PC494_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDF3910575.1"
                     /translation="MINKLEIRNLNFNYKNKKALDNINLTLTDGVVALLGPNGAGKST
                     LMRLLVTLYETSIGEIELNNIKYSKNNEKIKANVGYVPQDFDMYNNINGQEYLEFVAK
                     MRGVSKNDLKKHIQKVVSKVNLDKFINKKIGTYSGGVKRRLGIAQALIGDSKLIVMDE
                     PTVGLDPEQRNEFRRLLPEISKNSIVLISTHIVEDIQFNCDKLIILNQGKILYDGTIN
                     KFIDMVEVYSVVVSNDEFEYLERNIDIIDYRRVKDGVQVKYIGKNTEKLKDSLRIDTT
                     LQDAYINFLHKELK"
     gene            complement(44237..45946)
                     /locus_tag="PC494_000042"
     CDS             complement(44237..45946)
                     /locus_tag="PC494_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3910576.1"
                     /translation="MSSIKVISDFITKIIRKNILFAITIIIINYHLIQRWTHISNRGI
                     SFNDYLSLSVYTCMTISILTMLNVIFYMRKSYDTVKILCRNNFDYFLGISVAVTRNNF
                     IFCCIPIIYAIAYSSLIRTLSIVTIKSTIFILIFEWFLPLTILSIVISFISVIINNLI
                     LKITLSSVFLYLTSTNMLDRVIDIKEPFFKALFKSLNIFEDQSYAYYSDFVGKVNNSA
                     YVIDKIIPTLFAITLIIVAYLILNDIRKKQIKSLIVIVVYSILFIGLNYISIDMSTYR
                     DEERSYGEYLKKSNISDIKIKSHDMKIDFKSKSNIKDRIVLLNTSNEELTNINMILDE
                     IFDIKYIKINSENIKFNKKKDLIEVNLKESLEPNDEVTLDIEYEGYINVLTSWNQNKY
                     IATKDDIMLPPGSLAWYPKVNQSSCMAYKINLSSKNNVYSNLPLLNKTSNFLKKDYIF
                     EGKSNDIAIYAGEFKEEVKDDIKIIYPSDSNVNMDIEEKIKFLIETRNEILGDSKASV
                     DAKKYVDEVDNVMESIKRKKINMILVADLPSNEFLYEDSKGEKISITIYHWLSGNILI
                     IDK"
     gene            complement(46029..46403)
                     /locus_tag="PC494_000043"
     CDS             complement(46029..46403)
                     /locus_tag="PC494_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3910577.1"
                     /translation="MNLKKKIKKLGVTFAIGTIIVSSLGTSVFADEVSTYALISKAFS
                     GKNNIISSSVYTSGSRTFKTTDSQGGFSCRLTERFSGSSPDRIVKRHEANASSKVSLS
                     GGTYYIRYEGSTNNAKTYATLN"
     gene            complement(46660..47241)
                     /locus_tag="PC494_000044"
     CDS             complement(46660..47241)
                     /locus_tag="PC494_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory gene regulator B family protein"
                     /protein_id="HDF3910578.1"
                     /translation="MFKRLSYKFANILVNNEIVESEDFEIYRYGFETLIYFIVNILVA
                     LFIGIIFDRFIHTVIFLSCYCTLRQFTGGYHARNYKECTLTFVVIYLITIFSANNIDI
                     NKYKYLLVLLMIISILTIYKLAPLEHRNKPLSESEKKHYRKTVQKILFVIICLIILCK
                     ILNIFQQYVIYAIISIYWIAILIYIGMKVNSDQ"
     gene            complement(47300..47440)
                     /locus_tag="PC494_000045"
     CDS             complement(47300..47440)
                     /locus_tag="PC494_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic lactone autoinducer peptide"
                     /protein_id="HDF3910579.1"
                     /translation="MKKIALNLLKNISALSFGIAVLSANSASSWVAHQAKEPQALQKL
                     KK"
     gene            complement(47452..48768)
                     /locus_tag="PC494_000046"
     CDS             complement(47452..48768)
                     /locus_tag="PC494_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HDF3910580.1"
                     /translation="MLTNLSVGFWNIINLVSGTIDWIIFFLVIHLVGKRKISNIRYIF
                     TTIIIIIFMAYINVVKVFPNIKILLCMVIGISFYITSYEDKIYKSIIVSLLFWLGLMV
                     AEGSAVGLVVFINKLNNINITQHENLFRIQAIIMSKVFLFIGFILFKYFKLSLDFKPK
                     DMILIGIPILSNIVSLLLIFEYNLRVNTITTENLFIFIFAILLILSSSIILLIVIGKI
                     VQDDKLNLEYELINERIKTNYRNYENINEVHDRLKYVYHDLKNHMICIKNYDTKEEII
                     SYINNLEFQISEFEHFKNTGNKTLDLILAEKISICKKYDIQIEDNINISKLNFIKNND
                     ICSIFANSLDNAIEACMDINNEIEKRIEVKATYINKFAIIKFINTKVNDIKLIDKRIQ
                     TSKDDDNIHGIGLASIKYIVNKYGGETIVNYSDNEFILKIMIPIKS"
     gene            complement(48762..49472)
                     /locus_tag="PC494_000047"
     CDS             complement(48762..49472)
                     /locus_tag="PC494_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF3910581.1"
                     /translation="MINIGICDDELHYRIKIKDILSEILSSYPINYNIYEFSAGEELL
                     NNYPKDLDILIMDIQMKTINGMDTARKIREFDHKLEIIFVTSFVEFMQEGYEVKAYRY
                     ILKPINKEKISKSVLPCINEMMKKRNNYLTINVKNYVDRIKIDSITYIETDRPNILIY
                     THDDMYITKMSISKIEKILNEYGFFRCHNSYIVNLKLVESMSGSTVIVDGKSIPISKY
                     RVKGLKLAITNILGDIVC"
     gene            complement(49911..50486)
                     /locus_tag="PC494_000048"
     CDS             complement(49911..50486)
                     /locus_tag="PC494_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1062 domain-containing protein"
                     /protein_id="HDF3910582.1"
                     /translation="MKKITWEVEYISQLPVIRYCKKCGKKTEYICSGLFRVNAQHKYL
                     DIWLIYKCSNCDSTWNSTIYSRVNPNRLSTETLEQFHTNDDNLANQYAMNVELLHRNG
                     AEVGIPEYKIVGQEIDINDLTQVRIVSKYPSQLKVSALLREKLGLSRKAFDEMLDCGT
                     IKSISGVDLRRSKLNYEIVLEVGKQKQKSSN"
     gene            complement(50779..51057)
                     /locus_tag="PC494_000049"
     CDS             complement(50779..51057)
                     /locus_tag="PC494_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3910583.1"
                     /translation="MSYKKAIHILPEELLELIQEYVDGECIYIPRKSNNKKEWGSNTP
                     TREELSIRNMQIYEDYQVGYDLQYLSEKYYLSLKSIQRIVLQEKRKDI"
     gene            complement(51366..52127)
                     /locus_tag="PC494_000050"
     CDS             complement(51366..52127)
                     /locus_tag="PC494_000050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase"
                     /protein_id="HDF3910584.1"
                     /translation="MKNKIEISMNNFVKNYHKSNNITTKWQELLFAYASAEDDMFQKL
                     KSVVGTSHAMPKDFLENGKTIITYFIPFDESVNNSNIGGFECSEIWARAYIETNMLIS
                     NLNDFLCEELEKMGANSYAIPGSYNFDSEKLVSDWSQRHVAFIAGLGTFGLNNMLITE
                     KGCCGRIGSIITSLELEPTKRPENEYCLYKHNNSCKKCVNKCVKEALKEDGFNRNKCY
                     EMCMINEKKYTYIGGCDICGKCIVGVPCSVINPSR"
     gene            complement(52296..54362)
                     /gene="bclA3"
                     /locus_tag="PC494_000051"
     CDS             complement(52296..54362)
                     /gene="bclA3"
                     /locus_tag="PC494_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-like exosporium glycoprotein BclA3"
                     /protein_id="HDF3910585.1"
                     /translation="MLLIMSRNKYFGPFDDNDYNNGYDKYDDCNNGRDDYNSCDCHHC
                     CPPSCVGPTGPMGPRGRTGPTGPTGPTGPGVGATGPTGPTGPTGPTGNTGNTGATGLR
                     GPTGATGATGPTGAIGFGVTGPTGPTGATGATGADGVTGPTGPTGATGADGITGPTGA
                     TGATGFGVTGPTGPTGATGVGVTGATGLIGPTGATGTPGATGPTGAVGATGIGITGPT
                     GPTGATGADGATGVTGPTGATGADGVTGPTGATGATGFGVTGPTGPTGATGIGITGAT
                     GLIGPTGATGATGATGPTGVTGATGAAGLIGPTGATGATGADGATGATGATGATGPTG
                     ADGLVGPTGATGATGADGLVGPTGPTGATGVGITGATGATGATGPTGADGLVGPTGAT
                     GATGADGVAGPTGATGATGNTGADGATGPTGATGPTGADGLVGPTGATGATGLAGATG
                     ATGPIGATGPTGADGATGATGATGPTGPTGADGLVGPTGATGATGATGATGPTGATGA
                     TGATGPTGASAIIPFASGIPLSLTTIAGGLVGTPGFVGFGSSAPGLSIVGGVIDLTNA
                     AGTLTNFAFSMPRAGTITSISAYFSTTAALSLVGSTVTITATLYQSTAPNNSFTAVPG
                     ATVTLAPPLTGILSVGSISSGIVTGLNIAATAETRFLLVFTATASGLSLVNTVAGYAS
                     AGIAIN"
     gene            complement(54429..55505)
                     /locus_tag="PC494_000052"
     CDS             complement(54429..55505)
                     /locus_tag="PC494_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HDF3910586.1"
                     /translation="MITISLCMIVKNEEEVIGRCLECVKDIVDEIIIVDTGSTDSTKE
                     IVSKYTDMVYDFEWIDDFSAARNFSFSKASKDYTMWLDADDIILEADREKLLKIKESL
                     DTSIDIVMAKYNVSFDENGNPTLSYYRERLFKRSSNHKWVDPIHEVVPLFGEVFYSDI
                     AISHKKLHRQDPLRNLRIFEKMISEGKTLEPRHQFYYSRELYYNARYKEAIEGFTKFL
                     DSSRGWIEDCISACRDLATCYYLINDEKSALYSLFRSFEFDEPRAEICCDIGKHMFDR
                     QKYKEAIFWYKVALTRDKNDTNGGFKSNDCYGYIPSIQLSVCYDRLGESDKAIYYHEK
                     TKEIKPNDSAVLHNENYFSKFKNS"
     gene            complement(55817..56401)
                     /gene="clpP"
                     /locus_tag="PC494_000053"
     CDS             complement(55817..56401)
                     /gene="clpP"
                     /locus_tag="PC494_000053"
                     /EC_number="3.4.21.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp endopeptidase proteolytic
                     subunit ClpP"
                     /protein_id="HDF3910587.1"
                     /translation="MSLVPHVIEQTGQGERSYDIYSKLLKDRIIFIGEEINDAIASLV
                     VAQLLFLESEDPDSDIIIYINSPGGSATSGFAIYDTMNYVRCDVSTICIGMAASMSAF
                     LLAGGTHGKRCALPNSEIMIHQPMGGAKGQATDVKIAVDNILKIKERLDKILSENTGK
                     SIEDIRRDTDRDNFMTALEAKEYGLIDYIMNRNE"
     gene            complement(56398..56856)
                     /locus_tag="PC494_000054"
     CDS             complement(56398..56856)
                     /locus_tag="PC494_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF3910588.1"
                     /translation="MEIIDYIEENLTENLNLDKIAYIANYSKYHLHRMFTNVVGCTIH
                     QYIQRRRLTEAARQLIFTDKYIIDIAITVGYSTHQSFTLAFRNLYKESPQVYRNKDEF
                     YPIQQRFVLNLNHQIQSEKCISYANMNYKQRRDEINSYLNFNINCEVKVA"
     gene            complement(57079..58494)
                     /locus_tag="PC494_000055"
     CDS             complement(57079..58494)
                     /locus_tag="PC494_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HDF3910589.1"
                     /translation="MWITINRNSNISLSRQIYCEIKDMILDGSLKFEQKLPSSRTLSK
                     ELSVSRNTVLDAYNQLIAEGYLETRNGYGTIVAKGISGHKVDFKLNDTFRDEKDLHTN
                     KQKNYIDFRSGVPELKLFPRKELSKLYKQILYDLSDSDFRYGSTAGVWVLRVEISKYL
                     FRTRGIRCNPKNIMIVSGSTQGLSLISQLLYKSNKKVAVEDPIHKGLLKVISSIGYSV
                     VGIKVDDKGMNTNLIKSIKGISFVYTTPSHQYPLGGILPIQRRLELIKCATENDYYII
                     EDDYDSEFRYEGQPISSLYELSPNKVIYIGSFSKILSPAIRVGFMLLPDNILESYKTL
                     KMYSDVHTETILQHVLAEFIGNGGLEKYIFRMKKLYNRKRKYLIKVLNTEFKNEFKIK
                     GEAAGLHIVAHFYNVKFTESLIHKIFEAGIKVYPIQQYAIENILEYDYEIILGYAHLS
                     FDEIEKGVKILSKIIHMNQGT"
     gene            58609..59277
                     /locus_tag="PC494_000056"
     CDS             58609..59277
                     /locus_tag="PC494_000056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA-binding protein"
                     /protein_id="HDF3910590.1"
                     /translation="MLEVSHKVKEIYPNIKFGVMVINITHSKPNKENFLVLKNSTIKN
                     IIEQHPEYNRKEKIKTEPVSSYIKYYKKFKKTYPVLLQLESILLKSKGIPDVGVTIES
                     MFLAELKNLLLTAGHDLDKMELPLKIELANGSEHFYGIGGKEHILTKDDLFLSDNIGI
                     LSSILNGPDNRTAITKDTKNIMYFVYGPDKISEKQIQDHLNDIKHYISSAFPDLKVNS
                     IDIF"
     gene            complement(59453..59971)
                     /locus_tag="PC494_000057"
     CDS             complement(59453..59971)
                     /locus_tag="PC494_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HDF3910591.1"
                     /translation="MNFVELAKKRYSCRNYQDRKVEKEKLEKVLDVARIAPTGGNRQP
                     QRLIVIQEKEGINKLSKAANIYDAPLAILVCGDKDKVWTRPFDGKQLTDIDTSIVTDH
                     MMLQATELGLASVWVCYFNPDIIREEFSLPDNLEPINILLMGYESKIPESPERHEKTR
                     VPLSEIVSYETL"
     gene            60123..60446
                     /locus_tag="PC494_000058"
     CDS             60123..60446
                     /locus_tag="PC494_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF3910592.1"
                     /translation="MKKCLDNYSCPIEATLALIGGKYKTLILWHLKDTILRFNELKKL
                     IPKATPKMLTQQLRELESDGLIIRVVYPVVPPKVEYSLSDFGKSIIPILDSMCDWGSD
                     YLENL"
     gene            complement(60451..61035)
                     /locus_tag="PC494_000059"
     CDS             complement(60451..61035)
                     /locus_tag="PC494_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DJ-1/PfpI family protein"
                     /protein_id="HDF3910593.1"
                     /translation="MKVLVFLAKGFETMEFSVFVDVMGWARNDYGHDIDVVTCGFKKQ
                     VMSTFNIQVLVDKTIEEVCVDDYDALAIPGGFEEFGFYDEAYDSSFLNLIREFNSKEK
                     IIASICVAALPVGKSGVLKNRKATTYHLKNGKRQRQLSEFDVNVVNEPIVVDKNIITS
                     YCPETAPHVAFKLLEMLTSKEQMDEVKLAMGFKL"
     gene            complement(61084..61539)
                     /locus_tag="PC494_000060"
     CDS             complement(61084..61539)
                     /locus_tag="PC494_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Lrp/AsnC family transcriptional regulator"
                     /protein_id="HDF3910594.1"
                     /translation="MDEIDLKIINSLKKNSRASTSEISRQINLSVPAVSERIRKIEQS
                     NLIQKYTIQINREKTKYKLLAFIFINTDLSKSMKEFKKTILEYDTVLECHHISGEYDY
                     LIKVLAEDTSNLEEFISVTLKEIGGIQKANTTIVLSTIKEEFNTIKDIF"
     gene            62421..63959
                     /locus_tag="PC494_000061"
     CDS             62421..63959
                     /locus_tag="PC494_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HDF3910595.1"
                     /translation="MSLLKVTNLSQCFMDKSLYEKANFDLFKGEHIGVVGQNGTGKST
                     LIKILLGEVVPDSGEIKWQPNINIGHLDQYAEINRDTTISLYLHTAFEELYKIEKEMN
                     LLYQKSAISENEQYLIKASDYQEQLIASNFYSIDNEINKIANGLGLDSIGMNRVVREL
                     SGGQRAKVILAKLLLSNHDVLLLDEPTNFLDKEHVEWLSNYLNTFNGAFIVVSHDFDF
                     LEKISTGILDIEFGMIKKYHGKYSEFLKQKSHLREDYIRRYQAQQKKIEKEETFIRKN
                     KAGVNSKIARGRQKQLDKIERIAPPSFTGKPNIQFSEIEISAQNALTITNLEVGYYYS
                     LLPKLNFSVDGGQKIVITGFNGIGKSTLLKTLVKDIPRISGDFQFSEQVKIGYYEQDL
                     KWENPDKTPLQIVADKYPKLNTKEIRRHLARCGVKEEHVSRSVSTLSGGEQSKVKLCC
                     MMLSPCNFLILDEPTNHFDAETKDALQNALKQFRGSIILVSHEEKFYKGWIDKVFNIE
                     KQLV"
     gene            complement(64231..64944)
                     /locus_tag="PC494_000062"
     CDS             complement(64231..64944)
                     /locus_tag="PC494_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF3910596.1"
                     /translation="MDTCFNKKILLVDDEKDIVDLIEEVLINDGFKNIIKAYNGLDAI
                     SLCKIACPDVVILDIMLPDIDGIEVCKKIREFSYCSILFLSSKNDDIDKILGLSSGGD
                     DYITKPFSPREIAFRVKAQLRRQQYQSIVPSDSEVIKIGDITIDIEGNRVYKDRNEIE
                     LTGREYHLLSYMAQNVNKIIGKERLYEQVWGVYSSICDNTIMVHIRHIREKIEDNPSN
                     PKILITVKGLGYKLVNRID"
     gene            complement(65392..66771)
                     /locus_tag="PC494_000063"
     CDS             complement(65392..66771)
                     /locus_tag="PC494_000063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HDF3910597.1"
                     /translation="MSDVYYSENHEQDNLYEQDNLLAQRFNLFTLLKFAFPTIFMMIF
                     MGLYTIVDTIFVSRFINTNALSAINIVCPIINLIVGIGTMLATGGSAIVARKMGNGDI
                     EGANKAFSLIVLSGVVIGVIITGIGIVFMDYIIIWLGASEVLIKYCRSYLFIILVFAS
                     ANILQVLFQCLFVTAGKPQFGLWLVLGAGCANIILDYVFIVLLQMGISGAALATGVGY
                     LIPTVSGMVFFSKNKGLLKFCIPRLDKRILFEACFNGSSEMVSQLSTAVTTFLFNAMM
                     MKLIGEDGVAAITIIIYSQFLLTSLYIGFSMGVAPIISYNYGSENNTQLNHVFKICIL
                     FISVASLLVFIFSISCSPIIVEIFSQRGSRVYEIARSGFYIFSFSFIFCGYNIFTSSM
                     FTALSNGKVSAILSFLRTFGFITIGLLILPNILNINGIWLAVPSAEILTLFLTIFCIC
                     KYKNRYKYM"
     gene            complement(67056..67850)
                     /locus_tag="PC494_000064"
     CDS             complement(67056..67850)
                     /locus_tag="PC494_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 family transporter protein"
                     /protein_id="HDF3910598.1"
                     /translation="MMKKNLKIIFMLLKMKLSKMMVFRFDFFGAFFVDSSLFILQLLM
                     FNSIYSHVDSIGGWKQGEMLIFIGTFSLINAINMTIFFFGIYDIPRKIQEGELDYYIT
                     KPLDPLFRLTFENINIGSSPLILASILIVLYGISELNSEITLAMIIIYIFMVLLMTLL
                     FYDVCIILRTVSFFVISSSAIMRLEDNLLPMNMKIPGVIYEGVFKVLFYLILPYGIMS
                     TIPTQILAGTITINGLIYSILIVFLFTLFMWRFWKLGMRHYKSASS"
     gene            complement(67847..68710)
                     /locus_tag="PC494_000065"
     CDS             complement(67847..68710)
                     /locus_tag="PC494_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 family transporter protein"
                     /protein_id="HDF3910599.1"
                     /translation="MSIMSNYNEASSNYSMFYKFKQSIRRYYEVAKINFKVQLIWRFD
                     VVVNMVFTIVKILFAYILWKAIFGENKIVSGFTFNSMLSYYIISSFLAGIDMSKSTSE
                     EICNRVKLGTFSKYMIIPINVQNYFIAKNFGMTCFYFVFNMISAFVWIFIFKIDFAFT
                     SNPVQILISILMIFLGFIFMMKLHFFIGILSFKFLEISFFRMIIENIVEFITGTMIPL
                     VLLPETIVTVMKVFPFYYTTYLPSMLLIGRNSNEAIQGLIILALWVLFFSVVNKVMYK
                     RMRTLFDGVGI"
     gene            complement(68688..69683)
                     /locus_tag="PC494_000066"
     CDS             complement(68688..69683)
                     /locus_tag="PC494_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDF3910600.1"
                     /translation="MSIIELNELTKSYRRFEKKAGFMGSVKSLFNRKYTEKTAISSFD
                     LKIEEGEFVGLIGQNGAGKTTLIKMLTGIIAPSSGEISVMGYYPNKLENNFKKQYAVV
                     MGQKSQLFFELTPADTFLLFKELYDISNEEYKKNLDYFIELFEVSDYLNVQVRTLSLG
                     ERMKMELIVALLHNPKILFLDEPTIGLDAIAQKQIRYFLKEVNETKGTTIILTSHYME
                     DIKSLCSRSIVVENSRKIYDGSTEKLFNYFQKYKKITVSFSNETNIVFPKDCKVVEQT
                     NHKTSVIVPKERGNETIKWIFDKYDVKDVMIEEEDIGSIVERIYKKGSDEYYEQL"
     gene            70387..71343
                     /locus_tag="PC494_000067"
     CDS             70387..71343
                     /locus_tag="PC494_000067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HDF3910601.1"
                     /translation="MENNTIQKQLRDLSKKIWHIYILNPEEENLKFIISLLDDNLALI
                     GTGKHEFYETLEEFIIGLEKDQTESEQIDFEIIDEWYSCTKVTDEAFIVYGTLWVIEK
                     DYLEKDIYVEMDTRFTMVYRVTDDMIKLIHVHHSIPNFDQMKDEYYPKTITEKAQEAL
                     AMANEFKLKSEKDLMTGLYNRHFFEVHIKKMLKTVSHGYFYIFDLDNFKQVNDIFGHV
                     RGDEILIHFSNILTKVFVNDAIIGRLGGDEFAVFEYSNQSKENVENKAKKVLELCLES
                     NSCSIGISKLENNSDTFQSLYKQSDYALYYSKRNNKGNFSWF"
     gene            complement(71745..72635)
                     /locus_tag="PC494_000068"
     CDS             complement(71745..72635)
                     /locus_tag="PC494_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3910602.1"
                     /translation="MKKNILTTVITMIIILMMSMTVMAEPYQEDETSSLKKQSANERN
                     QTNIGTMDGRVQTNAISKGDNYDPKYPLKGMLTQLGLNTTGKEGWDLLYGGNPNGVEL
                     RADGKYYYINKGMEGLGFYAAALSGGSYQRIGFGKLDPIEVIADGNWISYKQAQDTLT
                     VIRNFLNSFDWRNASEMERANRAAKLVTEAKYADSKYCNIVYGNLVDKRGVCGSFASS
                     FHLLTRLMGMDSLSILNPSLNHAWNYIQIDGKWYRFDGSEISAFGGSLDFDYRKLKDA
                     TREMTTYYDAKALSILGFNQ"
     gene            complement(72813..73499)
                     /locus_tag="PC494_000069"
     CDS             complement(72813..73499)
                     /locus_tag="PC494_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3910603.1"
                     /translation="MKISSQYRSQYSFRYESNINNTRINESMVKKNETVGKDTYLSNI
                     MKQKQELNDRIRDLKYRQEVYTKKINDAIKNLCKSEIRETTNNFSNIEIGIKNSIIED
                     KNKSTMLDENSTYLNTNDEKESLITKESNEKIEEEILNDEKLEELEQKKDSNKKEKVS
                     EDLSLVGKTREELENMLKNFINLTQEEIMKLESRIEKLDKNAEEYKQNSKTNIFDKTD
                     EQKKHINVLI"
     gene            complement(74035..75102)
                     /gene="rsgA"
                     /locus_tag="PC494_000070"
     CDS             complement(74035..75102)
                     /gene="rsgA"
                     /locus_tag="PC494_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HDF3910604.1"
                     /translation="MNGMKQINLQDYGLNRNFITQSMEYYDLYLARIISQEKNFYQAV
                     CVNGVLFAEVSGKLRFEATIQSDFPTVGDFVMLDRCNNKNGNAIIHHVLHRKSLFVRK
                     AAGKVNEEQVVAANIDIVFLCMSLNKDFNIHRLERYLSLTWESGAIPVVVLTKSDLCD
                     NVHRKLQVVNSIALGVDVVVTSSIEPDGYKQISKYIKPGCTVALLGSSGVGKSSLINC
                     LMGGEFLNTKEIRIDDDKGRHATTRRELFLISGGGIVIDTPGMRELGMWDVSEGLDKS
                     FADIEAYFGKCHFRNCTHTSEPGCAIWEAIAHQELSPKRWESYRRLKAEAVFADNKSE
                     YLAKKEKKFKNISKINKTIRR"
     gene            complement(75099..75500)
                     /locus_tag="PC494_000071"
     CDS             complement(75099..75500)
                     /locus_tag="PC494_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNHCP domain-containing protein"
                     /protein_id="HDF3910605.1"
                     /translation="MNYKNRKRAYYQENSCMDNFICKNCGCLVVPEGAGTQHRNHCPH
                     CLHSLHVDIIPGDRAADCDANMEPIGVWVRKNGEWAIIHRCTRCGHLSSNRIAADDNS
                     VKLMSIALKPLAQPPFPLERIIEKLEKEETE"
     regulatory      76296..76392
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            76446..76622
                     /locus_tag="PC494_000072"
     CDS             76446..76622
                     /locus_tag="PC494_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3910606.1"
                     /translation="MFRDKMDRCTHMLTAYIGSSYDYCDFIDTQLDDFILEYGENVVE
                     SCLHQVMVLVSKYN"
     gene            77032..77670
                     /locus_tag="PC494_000073"
     CDS             77032..77670
                     /locus_tag="PC494_000073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3910607.1"
                     /translation="MSNQRKDFDITNDMFQESIPITTKIILEDMPSNDELNHVFSKGC
                     ERKMKKRKIVLITLLLIGVLLLGSILYNLFLGKTANISMLKESWNFDIPIPNKEIEVF
                     DTQDSINGDGQSYFIQGFSEKNFKKVFNLKGGIVVSKDNINEIEKYIDKFKRDSVNIN
                     KSNKNKIEEDFKKYKLEVKKDDKYIYKRNYENYVVLIIKKDEQKLYSLIWNQ"
     gene            complement(78148..79506)
                     /gene="rlmD"
                     /locus_tag="PC494_000074"
     CDS             complement(78148..79506)
                     /gene="rlmD"
                     /locus_tag="PC494_000074"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HDF3910608.1"
                     /translation="MLSKNEMYIVDIVDIGQGGVGVGKYNGITVFVEGGLIHDKVKVR
                     INKVKKNYAVGDIVEIIEKSPFRVKRVCSDNLRDCGGCQIQDLDYNKQLEMKTNEVKQ
                     VLSRIGKLEDVEVHDTIGMDNPYRYRNKAQFPIQKNNGIPIIGFYKKKTHDVISTEKC
                     VIQHEINDKIVKIIKTYIRAYKVSIYDEKTHTGLIRHLVTKIGFTTKEVMVVLVANGN
                     KLPYLKELASVLKENIPGFKTLVVNVNQKDTNAILGRENIVIYGDGKINDYIGDLVFE
                     ISPLSFFQVNPVQTKVLYDKALEYANLNDTDTVFDIYCGIGTISLFLAQKAKKVYGIE
                     IIDDAIKDAKINAKLNNIHNAEFYVGKAEEIVPKMYREGKTANVVVVDPPRKGCDEKV
                     LETIVSMNPERIVYVSCNPSTLARDLDYLNVHGFKCVEAQPVDMFPHSTHVETVAKII
                     KQ"
     gene            complement(79681..81441)
                     /gene="pyk"
                     /locus_tag="PC494_000075"
     CDS             complement(79681..81441)
                     /gene="pyk"
                     /locus_tag="PC494_000075"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HDF3910609.1"
                     /translation="MLNNVKKTKIVCTLGPASQSEEVLTQLMQNGLNVCRFNFSHGSH
                     EEHKERIDMAKKVREKLNKPVAILLDTKGPEIRTGNFEDPEVFLEEGQKFTITMKDIM
                     GTKEMCTVSYKGLAEDVKSGDSILIDDGLVGLRVKEINGEDIVCVVENSGIVKNHKGV
                     NVPGVKINLPAITPKDISDIEFGISQGIDYIAASFVRKASDVLAIREVLENNNATDIQ
                     IISKIENQEGVENLDEILKVSDGIMVARGDLGVEIPTEEMPIVQKMMIKKCNELAKPV
                     VTATQMLDSMIRNPRPTRAEVTDVANAIYDGTDAIMLSGETAAGKYPVEAVKMMATIA
                     KRTEETLDYDRLLKENGTNNVTVTDAISHATCTTAVDLNASAIITSTSSGYTARMVSK
                     FRPKSPIIATTNNEKTMNKLALTWGVYPVKSSVAGNTDEVIEKAIEAARQADYIDNGE
                     LVVITAGVPVGVSGTTNLIKVHVISEEIVQGIGVGTQTVEGKVRIIKNGNACVDFNEG
                     DILVSTATDAEMNNYIEKAGAVVTENGGMTSHTAIVGINLDIPVIVSAADITNLVKDG
                     EVVTVDASRGVVYRGSTRVL"
     gene            complement(81493..82452)
                     /gene="pfkA"
                     /locus_tag="PC494_000076"
     CDS             complement(81493..82452)
                     /gene="pfkA"
                     /locus_tag="PC494_000076"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HDF3910610.1"
                     /translation="MKTIGLLTSGGDAPGMNAAIRAVVRSAIYYGCKVYGINRGYKGL
                     LEEDLTEMNLSSVGDIIHRGGTILKSSRCEEFKTEEGRLKAVKILKKYKIDCLVVIGG
                     DGSFAGAQKLSDLGFPAIGIPGTIDNDLAYTDYTIGFDTAMNTIIDAIGKIRDTSSSH
                     ERVNIVEVMGRHCGDLALYAGLAGGAETIIVPEVEITVDEVALRLKTTQKRGKRHSII
                     VLAEGVGSASDLEKELKKESGADLRVTVLGHVQRGGSPTVSDRILASRLGVRAVELLL
                     DGKSARVVGIKENKIIDLEISEALAQKKVFDKEAYEMAKILSI"
     gene            complement(82661..86230)
                     /locus_tag="PC494_000077"
     CDS             complement(82661..86230)
                     /locus_tag="PC494_000077"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HDF3910611.1"
                     /translation="MNKDFAHLHVHTEYSLLDGFSRVKKLIKRAKELNMSSIAITDHG
                     CMFGVIDFYKTAIKEGIKPIIGCEVYTAARGLRDKDPNYDKYQGHLVLLAKNMEGYKN
                     LIKIVSTSYVEGFYYKPRVDMEELKKHNKGIIALSACLAGDVARALMNRNYEKAKQFA
                     LDYRDIFGEENFFLEIQDHNLPEQKEVNSGLVKLSKETGIPLVATNDVHYVNKEDSKI
                     HDVLMCIQMGKTLNDPNRMRFGSDEFYLKSREEMEELFPYALEAIDNTVKIADMCNVE
                     FDFNTIHLPKYDVPEGYTPETYLRELCFNGLKERYDNPSNEILERLNYELDVIEKMGY
                     VEYFLIVWDFINFSKENNIIVGPGRGSAAGSIVAYTLKITDIDPIKYSLLFERFLNPE
                     RISMPDIDIDFCYERREEVIDYVKRKYGDDHVAQIITFGTMGAKAAIRDVGRVLDIGY
                     NKVDKVAKEIPFALGMTIDKALDTNPNLKELYDQDPETKEIINISKQIEGMLRHASTH
                     AAGVVISKNPVDEYVPLYKHQDAITTQFTMTTLEELGLLKMDFLGLRTLTVIRDTLDL
                     IEKNRVIKNYTEKIDFSKMDYDDPKVYEMLSSGNTLGVFQLESAGMRSFMKQLKPDNF
                     EDIVAGISLFRPGPMDSIPAYIKNKSNPKDVTYLHEKLKPIMEVTYGCLVYQEQVMQV
                     VRDLGGYSYGRSDLVRRAMSKKKMDVMEEERQYFIHGKFDEDGNIEIAGCIRNGVEEE
                     IANKIFDDMIDFARYAFNKSHAAAYGVLAYETAYLKTYYPVEFMAALITSVMGNTDKV
                     VEYIRECKALEIDVLPPDINKSFSKFSVEGDNIRFGLAAVKNVGVNIINNIIAERESN
                     GLFVDLVDLVKRLDQKDTNKRVIESLIKCGAFDNISENRASLMAGYESLLESVSMDRK
                     KNVQGQISLFDAFGDSEEDSDFQQIYSLPKRQEYEERERLNLEKEVLGMYVSGHPLSQ
                     FEKELQEKTSMDNGKLNSLKEEEESYLQMNETDVIMGGMIVTKTIKTTKRNEIMAFIE
                     LEDLYGAIEIIVFPQLLQKYNVILNEDNIIYVKGTLSIKEGENAKLIAREIKDINDDT
                     DFADRNYNSGRTRNVENIKPESGKKLYLKIDSMSDTDTTNNIVEIAKQYPGNDSIYLY
                     PMDENINGKRKAYKMTGALTCICDEFINNLEELLPKDNIKVKA"
     gene            complement(86387..87334)
                     /gene="whiA"
                     /locus_tag="PC494_000078"
     CDS             complement(86387..87334)
                     /gene="whiA"
                     /locus_tag="PC494_000078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HDF3910612.1"
                     /translation="MSFSTETKNELARVISGNECCNIAELSALVKSGGSIQIVGYKKL
                     NLKITTELNSIARKVFKLLKKNFNINTTISVNKNQMLKRNNSYVLMVTSEMGSEMLLK
                     KLGILEDKEGFFTINKISENLIKHEGCKRAFIRGAFLGGGSISDPEKNYHMEFVTNNE
                     EFADSLKELINSLGFNSKIVARKNNHVVYIKESEQISDLLSIIGGHHALLSLQNTKIV
                     KEMRNNVNRIVNCETANLSKTVNAAVRQVENIKLIQETIGISSLPENLQEIAKIRIEY
                     EDMTLKELGEMLEPPIGKSGVNHRLRKIEEIATDLKKKS"
     gene            complement(87351..87776)
                     /locus_tag="PC494_000079"
     CDS             complement(87351..87776)
                     /locus_tag="PC494_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HDF3910613.1"
                     /translation="MREEVSAGGVVLFGNTILLLRKFNGDWVLPKGKVEEGENNQEAA
                     LREVSEETGVKADILKYLGEIHYTFKENWDENRAVHKTVFWYLMQAKNMDTIPQKEEG
                     FIDAKFIHLDRVVDLARYDDEKEIIKVALQEIKKRLKKN"
     gene            complement(87845..88951)
                     /locus_tag="PC494_000080"
     CDS             complement(87845..88951)
                     /locus_tag="PC494_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HDF3910614.1"
                     /translation="MAKLLIIVGILGWIALIVSLFIYKKAKNEKVKLFQRSIVENREP
                     NVVVIGGGTGQSVFLRGLKHTTQNITAIVTVADDGGGSGVLREDLGMLPPGDIRNCLL
                     ALANIEPTMNEVMQYRFTEGLLKGQSFGNLFLAAMNGLYGNFEKAVYKLSEIFAITGR
                     VLPVTLEDVNLVAKLENGNIINGESSIPEESKIQKSSIDKIFLNPKDVKPLKDVIASI
                     YDADIIIMGPGSLYTSIIPNLLVEGIVDAIKSSVAPKVYIANIMTQPGETEGYNVLEH
                     VNAIVKHTDENLIDYVIANNEILPEEMLDLYKQDGAEQVLLDKKQKDKLKEMGIKTVE
                     KNLIEIKNNYIRHDAKYISNIVIELALNHNYNKS"
     gene            complement(88963..89820)
                     /gene="rapZ"
                     /locus_tag="PC494_000081"
     CDS             complement(88963..89820)
                     /gene="rapZ"
                     /locus_tag="PC494_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HDF3910615.1"
                     /translation="MKFVIVTGLSGSGKSETMRALEDMGFYCVDNLPPALITKFAELC
                     YQPNSSIDKVALGIDIRGRKFFEALHESLNYLEKENYEYEMVYLDCNDDVLLKRYKMT
                     RRNHPLAKDMQIPEGIKMERKIMEPLKELSTCIIDTTNMKPKDLKEEIKKIYSSGEDN
                     PNLTISVVSFGFKHGILADADLVFDVRFLPNPYYVEELRAKTGDDKEVRDYVMNSKIS
                     EEFYVKLLDMIHFLVPQYIEEGKQHLVIGVGCTGGRHRSVTITNLIAEDLSNKGYRVV
                     KKHRDSMLR"
     gene            complement(89851..90564)
                     /locus_tag="PC494_000082"
     CDS             complement(89851..90564)
                     /locus_tag="PC494_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PHP domain-containing protein"
                     /protein_id="HDF3910616.1"
                     /translation="MKILADYHTHTLYSHGKGTIEDNVKVAISKGIKTIGISDHSYKH
                     IAYGVKKKDILKMREEVDYLNDKYTDINILLGMECNILDDKGNIDMDDKFIRDFDYIM
                     AGYHFGSTPTSLRSLLNHCNNYIFKTEKAKEYNTKAVINAISNNDIFIITHPGDKGDV
                     YIEEVAKTAKKTNTRLEINSSHSFLNVNQLNKIKGLENKFIIGSDAHCPERVGDFELA
                     MKTISDSNLDISLVENIII"
     gene            complement(90568..91482)
                     /gene="murB"
                     /locus_tag="PC494_000083"
     CDS             complement(90568..91482)
                     /gene="murB"
                     /locus_tag="PC494_000083"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HDF3910617.1"
                     /translation="MNNQDIYINLLNILSKEDIKVDEPMKKHISFRVGGPADILVRPR
                     TEEQLKNVLKLVKEESIPYLIIGNGSNILIKDGGIRGVVIELADNFNSYEINDTRMTA
                     QSGALLSVLGKALQKQELKGFEFASGIPGTLGGALAMNAGAYGGEMKDIVKSVRLMDM
                     EGNIFELSNEQMEFGYRKSIISKNGYIALSAELELQEGNYDEIKSLMDDLATRRITKQ
                     PLNFASAGSTFKRPTGYFAGKLIEETGLRGLTLRGAQVSEKHCGFVVNQGEASAKDIL
                     DLIYVIKSAVYAKFGVMLEEEVKILGED"
     gene            complement(91755..92525)
                     /locus_tag="PC494_000084"
     CDS             complement(91755..92525)
                     /locus_tag="PC494_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HDF3910618.1"
                     /translation="MSKGFLTPGETAQATISAGIKKANISTQNAILLGLFGGAFIGFG
                     ALGSMIVSQTFGKIDPGVASFLSAMVFPVGLMLVVVAGAELFTGNTLMAIALMDKKIT
                     LGKMLRNWGLVYFANLVGSILLVALVFYSSTLTGDAATKAIAVAEAKVNSTIASMFLK
                     AILCNILVVLAVWMATASQDIMSKLASCWTVIMLFVLCGFQHSVANMFFIPMGMALGA
                     NITMVQFITNLVFVTLGNIVGGSIVVGGIYYLCYVKNS"
     gene            92843..94324
                     /gene="cls"
                     /locus_tag="PC494_000085"
     CDS             92843..94324
                     /gene="cls"
                     /locus_tag="PC494_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HDF3910619.1"
                     /translation="MFDISFFEMSIYEIAVTTIYIINFMVILNLIFREKRNINTTLTW
                     LLILVLIPALGFILYIAFGRNISKNNMFRLKEKDDKIIKSNILDTQVKLQSTSEIDSD
                     IHQHKDMIYALANSNNAHYTNNNDVWIYAESSQFFNSLLEELKKAKKYINIQFYIFKD
                     DKIGTEIIDILIDKAKEGVEVRLLFDAVGGRTLKNSTLSRLKESGVKVGSFFPSFLKI
                     VNFNLNYRNHRKIVVIDGKVGFVGGYNVGDEYLGRNPKFGLWRDTHTKLTGDCVIDLN
                     MRFILDWRYTTKEDLDLEKYFIEEDTNSNHPSENIGIQIVSSGPDISELDEIKYGYLK
                     MIQKARKYIYIQSPYLILDSTFIDTLKIACLSGVDVRVMIPSKPDHPFVYWASYSYAG
                     ELLKFGAKIYTYGQNAFLHAKTIVIDDSICSIGTANMDIRSFELNFEVNAFMYSSKKA
                     LEQRIIFENDILNSKEITLDIYNSRSTYIKIKESISRLLSAVL"
     gene            94642..95139
                     /locus_tag="PC494_000086"
     CDS             94642..95139
                     /locus_tag="PC494_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase subunit E"
                     /protein_id="HDF3910620.1"
                     /translation="MCDFISHNKQLFDELDIFIDSLATKEGALIQVLHEAQGIFGYLP
                     KEVQLHVARKLGVAPAKVYGVVTFYSYFTTEPVGKYKISVCLGTVCFVKGADKILSAF
                     EKQLGIKVGETTSDFKFSLEGLRCLGACGLAPVVTVNGKVYGKVKPDQVSEILDTYRE
                     LELNC"
     gene            95156..97042
                     /locus_tag="PC494_000087"
     CDS             95156..97042
                     /locus_tag="PC494_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit NuoF"
                     /protein_id="HDF3910621.1"
                     /translation="MRKVNSFDELKVLADELKPNLSLRKNYSKENVLRRELLVCCDTG
                     CTSSNSLEIVSELENEIKKSGIQDKVSVRLTGCFGFCAQGPIVKVYPDNVFYVKVEPS
                     DAEKIVQSHLIRNTVVEELLYEEESLSKKVEEQEEMSFYKKQLRIALKNCGLIDPDSI
                     EEYIANDGYLALGKCLTSLTPQEVIAEVKTSGLRGRGGAGFPTGSKWEAASKNPAGPT
                     DKKFVVCNADEGDPGAFMDRSVLEGDPHSVLEAMAICGYAIGSDTGYIYIRAEYPKSI
                     ERLKVAIAQAEKYGLLGENILGTGFNFKLELKYGAGAFVCGEGTALMHSIEGRRGEPR
                     MKTYSSSKSGLWKSPTCLNNVETFANIPAIILKGGDWFANLGTEDSSGTKVFALGGKV
                     ENVGLVEVPMGTTLRDIVFEIGGGIPEGKKFKAVQTGGPSGGCIPTEHLDTPIDFGSL
                     SSIGSMMGSGGMLVLDESDCMVDIAKFFLEFTVEESCGKCTPCRIGTTRLLEILTKIT
                     EGNGTLQDLDDLENLAETIQTASLCGLGKAAPNPVLSTLQYFKDEYIAHVVDKKCPAG
                     KCQNLLSYFITDDCKGCTKCSRVCPAGCITGSVKEQHTIDTSKCLKCGACIDNCTFNA
                     IIKK"
     gene            97065..98846
                     /locus_tag="PC494_000088"
     CDS             97065..98846
                     /locus_tag="PC494_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron hydrogenase small subunit"
                     /protein_id="HDF3910622.1"
                     /translation="MSLVNLTINGKHVSAPSGTSILDAAKLINIKIHNLCHLHMNEID
                     KLDTCASCRVCMVETERGLVPACGTVIKEGMKVQTNSAKALNARRTIVELLLSDHPQD
                     CFVCEKNGDCELQTIAADLGVRKIRYQGSKSFAGKDTSTKSLVKDHSKCILCRRCETV
                     CNDIQTVGALSGVNRGFNTLVSTFFNSDMVETECTFCGQCISVCPTGALTEVDNVPKL
                     WDVLNKKEKTIVVQVAPAVRVAIGEEFGLEPGSISTGKMVAALKALGFEHVFDTNFGA
                     DFTIMEEATEFIERIQKGENLPILTSCCPAWVNFLEHNYPDKLNLASSCKSPQGMFGS
                     IAKNYYAPKILGINPEELYVVSVMPCVAKKYEASREELSESGILDVDLSITTRELAKM
                     IKEAAIDLPNLQDQDFDNPLGKSTGAASIFGASGGVLEAALRTSYEKITNKTLDNVNF
                     TNVRGLKGIREASIDVDGTTVNVCIVNTLKNARKIMDKVRSGECKYHIIEVMACPGGC
                     VGGAGQPYHHGNTEIVDRRANALYEIDRNKAIRKSHENPDLQAIYKDFFGEPNSDVAH
                     KYLHTHYFDKSCVYGECPQECACEEAK"
     gene            complement(98986..100782)
                     /locus_tag="PC494_000089"
     CDS             complement(98986..100782)
                     /locus_tag="PC494_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate oxidoreductase"
                     /protein_id="HDF3910623.1"
                     /translation="MGIEYFSKLLESSTEKELLLSKKSNNISTARLISFLIVIAGLAI
                     GFYNKNIVGIFVGVLSIIIFIALLVIHSKVKEEETYFKSKSEVLNKYIKRFGDGWKEF
                     KIDGKEYLKDENLQAKDLDLFGRASLYQYICVANTSYGKNFLAKYLWNENPDENVILE
                     RQRAIKELLSKDDFSIHIQTLSNIIGKEQKNNSDSSIESFIEYGENKNVYIPKWMHIF
                     TWGLPTATILSFIFCMLGFLPVLPVFLLFIIQLGFSGFGYPRLMQTLAPLFSFSRSIQ
                     VYEKMFEVLEKETFESAYLKELQDKLSKGSGVSRGVKQLNSIGNAVNLRYNQILYIIA
                     CGVLMWNYHCAEALERWKGIYGNQIRDWFESIGEFEALISLTVISHVKENTCFPVIKY
                     EDTPRLKVEEVYHPLIAEKSVIANSIQLNSQTCIITGSNMSGKTTFLRSIGVNLVLAY
                     AGAPVCAKSFDATCMAIFTSMRIQDDVSQGISTFYAEILRIKSMIQYSLKELPMLVLV
                     DEIFKGTNSADRIIGASEAVKKLSKPWVISMVTTHDFELCDLSGSGDVEVVNYHFSEY
                     YVDDKIHFDYKIKDGRCKTTNAKQLMRMAGIL"
     gene            complement(100996..101925)
                     /locus_tag="PC494_000090"
     CDS             complement(100996..101925)
                     /locus_tag="PC494_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr kinase/phosphorylase"
                     /protein_id="HDF3910624.1"
                     /translation="METSNKVSIREIIKELKLKVVYMPDDVDYYVYSQDINRPGLQFA
                     GYFDYFAYERIQIVGKTEYNFFGLMDSHIREEVLDRFFSYEIPALIISRDLEIKPDVI
                     EKAKKYKRILLSTNRNTTRLINRLSNYLDNKLAPHTTIHGVLVDIYGIGVLIKGESSI
                     GKSETALELIQRGNRLVADDAVEIRKLDESMLVGQSPELIRHFLEIRGIGIIDVRSLY
                     GVGAIKNSKMIDLVVHLEAWDETKYYDRLGLDKEYEEILGVNVEKLVVPVKPGRNTAM
                     ILEVAAMNFRQRGMGYDAAQEFTKKLSKLIDTK"
     gene            complement(101925..103742)
                     /gene="uvrC"
                     /locus_tag="PC494_000091"
     CDS             complement(101925..103742)
                     /gene="uvrC"
                     /locus_tag="PC494_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HDF3910625.1"
                     /translation="MFDIQEHLKKLPSEPGVYLMKDKYDHIIYVGKAISLKNRVRQYF
                     QSSKNHTSKVKSMVKNIYKFEYIITDSELEALILECNLIKRYRPKYNVVLRDDKTYPY
                     IKVTTNEDYPRILKVRRVLKDKAKYFGPYTNITAVNDTLELISSTYPIRSCKIDIDKA
                     IKNKTRPCLNLHINKCLGPCTGNVSKEEYGKMIEEIIMCLSGKEEKLMELLKEKMNES
                     SMNFRFEEAAVYRDKIKSLEEMIQKQKIDATVSDLNQDVVAMARAHNEACVQVFFIRN
                     GKIVGREHFILEGVMDSPRASILSSFVKQFYNEQEYIPKELIIEDEIEDSSILEEWLS
                     SKKGQKVTIRVPQKGEKKSLVEMVRKNAVEYLEKFSDMNKRKYEKSIGALEELKQILN
                     LEKLPIRIEAYDISNIQGVDSIGSMVVYTNAKKDKKEYRRYKIKTVIGPNDYDSMAEI
                     VDRRLKHGNLPDLILLDGGKGQVSAVKKVLELNDVDIPLWGMYKDDKHRTKGLICKEK
                     EIELDKTTNLYRFIASIQEEVHNYAITYHRSLRNKALTKSILDDIQGIGEKRKKSLLN
                     HFKDVDAIKKATMEELLEVDGMNKSIADNVYNFFRKEEN"
     gene            complement(104001..106826)
                     /gene="uvrA"
                     /locus_tag="PC494_000092"
     CDS             complement(104001..106826)
                     /gene="uvrA"
                     /locus_tag="PC494_000092"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HDF3910626.1"
                     /translation="MEDKIIIRGAKEHNLKNIDLELPRDKFIVFTGLSGSGKSSLAFD
                     TIYAEGQRRYVESLSAYARQFLGQMEKPNVEYIEGLSPAISIDQKTTSKNPRSTVGTV
                     TEIYDYLRLLFARVGDVYCPTCGEKISQMTIQEIVDKMLDFPDRTKLQILSPIVRGQK
                     GTHKKVFDNIKKEGFVRVRVNGENYEVSDDIILNKNQKHNIEVVVDRIVIKDGIESRL
                     ADSIETAVKLSDGLVIAQIIDGEEILFSTKFACPEHGIGIEELSPRMFSFNAPFGACD
                     VCNGLGESKEVDPELVVPNKDLSIKQGAVAAWGSTGVNDDTYYSKMIKSLAEHFNVSL
                     TTPFKDLPDDFVEELLYGKDNIIVEFTYESKFGGTRNYKSYFEGVIVNLERRYRETNS
                     DYMRDKIEEYMAERPCPKCKGMRLKKEVLSVLVDGKNIMEVTNLSVNELIDFMENINL
                     TEKQRFIAHEIIKEIKGRAMFLRDVGLDYLNLSRKAGTLSGGEAQRIRLATQIGSALV
                     GVLYVLDEPSIGLHQRDNDRLITTLRHLTDLGNTLIVVEHDEDTMREADYVIDIGPGA
                     GIHGGEIVAQGTLDEIIENENSITGQYLSGKKQILLPETTREGNGSFIEIVKASENNL
                     KNIDVKFPLGKFTCITGVSGSGKSTLINDILYKGVASKVNRLKQRAGKHKEIKGIESI
                     DKVINIDQSPIGRTPRSNPATYTGVFDFIRDIFASTNEAKARGYKKGRFSFNVKGGRC
                     EACKGDGIIKIEMHFLPDVYVPCEICKGERYNRETLQVKYKDKTISDILDMNVEEAVE
                     FFENIPNIKRKLETLMDVGLSYIKLGQPSTQLSGGEAQRIKLAAELSKRPTGKTLYIL
                     DEPTTGLHMADVDKLIQVLQRLADTGNTIIVIEHNLDVIKTCDYVIDLGPEGGDKGGT
                     IVATGTPKEVSKVDGSYTGQFLKKYFS"
     gene            complement(106845..108815)
                     /gene="uvrB"
                     /locus_tag="PC494_000093"
     CDS             complement(106845..108815)
                     /gene="uvrB"
                     /locus_tag="PC494_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrB"
                     /protein_id="HDF3910627.1"
                     /translation="MDFKIKSDFKPTGDQPEAIKSIVDSINRNEKFSTLLGVTGSGKT
                     FTMANIIQQVKKPTLIMAHNKTLAAQLYSEFKEFFPDNAVEYFVSYYDYYQPEAYVAH
                     SDTYIEKDASINDEIDKLRHSATASILERRDTIIISSVSCIYGLGDPKDYKELMLSIR
                     PGMQRDRDDVIKRLIEIQYERNDINFTRGTFRVRGDILEIFPASNDEKAIRIEFFGDE
                     VDRITEIDYVTGKIVGTRNHVVIFPASHYVTTPERIEKAIVEIENELQEQIKFFKEND
                     RLLEAQRIEQRTKYDIEMLKEIGFCQGIENYSRHITGRSEGERPYTLMDFFPDDYLII
                     IDEAHVTIPQVRGMYAGDRSRKTSLIENGFRLPSALDNRPLNFQEFEGNINQMLFVSA
                     TPGPYEIQHSETIAEQIIRPTGLLDPIVEVRPINNQIDDLVGEITKTIEKNERVLITT
                     LTKKMSEDLTNYLKEIGIKVKYLHSDIVTLERTEIIRDLRLGKFDVLVGINLLREGLD
                     IPEVSLIAILDADKEGFLRSETALIQTIGRAARNENGRVIMYADRITDSMQNAIDETK
                     RRRDIQNLYNEEHNIIPKTIQKNIRDSIEATKVAEEEVVYGISDTDDKDEIRANIDKL
                     KSEMMEAAQNLQFERAAELRDKVKQLEEKLEK"
     gene            complement(109002..110264)
                     /locus_tag="PC494_000094"
     CDS             complement(109002..110264)
                     /locus_tag="PC494_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline phosphatase family protein"
                     /protein_id="HDF3910628.1"
                     /translation="MTKVIVLSVDSLFEKDLEFVKNLPNFKSILENCSIVKNINCVYP
                     TLTYPCHTSMVTGVYPKKHGIYHNEKFDPNKENKDWYWYSKDIKAKTIIDVAKENNLT
                     TSSVLWPVMGANPNIDYNIAEIWAPSREDDPRETFERSSSKVIMDGIYNRHCHYIDWK
                     LEPNMDLFGVNCSVDIIKEYKPDLMLIHLATLDHTRHNYGLFNDEVDKALKMNDKWLG
                     DIIQATKDAGTYKDTNFIILGDHGHLRVDKVINPNVLLKSNGFIKVENGEVKDFDAYV
                     NSSGISAQIIVNNLDRLTELRELLEEFKEELFIENIFTKEEASNLGLEGDFEIVIEGL
                     EGISFGNDFEGSIIKDSDIKDYKFAVATHGHLPTKGNRPPFIAFGPNIKGGVVIEEGD
                     LRAHAATILKMFNLKLDGVEKEAFDFIM"
     gene            complement(110327..111631)
                     /locus_tag="PC494_000095"
     CDS             complement(110327..111631)
                     /locus_tag="PC494_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDF3910629.1"
                     /translation="MKLKRKLATGLAITLLLGSLVGCSNSNDANASKGEKTDSNITKI
                     DFWAPLGGTNGETAQKMVDQFNSEHKDVQVNMLKQKDYYENATKLQAALTSKDQPDVT
                     LLEITQTGTFASAGALVDMSKYFDKTYQERFFSGLLTNSYYEDKFVGMPFNRSTPILY
                     INKDMATKAGLDPSGPKSWEELKDYASKMTNKSEDTYGFETPIDIWFYEAMVMQSGGE
                     ITNGKKVAFNNEAGQAPVKFWQDMMKAGIMKMPPGEDYNAWDVAKQDFVNGKVGMIFT
                     STADLAGLMQQTEGKFEISTAFLPKNQKYATPTGGANLVMLEGGTDKEKEASAEFIEW
                     MTQTDKIVQFSSSTGYLPTTEDATNSEKLQTLYKEKPQYKVATDQLQYAVALPMLNGY
                     KEATDKLMDEIKKGLTDLNANPKDVVSKGTSAMQAVIDKTNK"
     gene            complement(111662..112522)
                     /locus_tag="PC494_000096"
     CDS             complement(111662..112522)
                     /locus_tag="PC494_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HDF3910630.1"
                     /translation="MDIIQPIKKDKVDIKKIASKSIEILILLLLSAIFIFPFIWMLST
                     SFKNPQEMMQLPPTIIPNDIVLENYSTAWHSGPFFRYLLNSVFVTGSVLIVQFLVMVP
                     AAYAFSKIKFKGEKMLFGLLLVGLMIPPQVTFLPVYMMMSKFGFINTYVPLIIPFMTS
                     SFGIFLLRQNFMQISDEIIEAAKLDNASDLKIMFRIMVPMAKPAVITFILFNFIYHWN
                     NYFWPLVMTNTDAIRTLPIGVALLKSSEGITAWNVIMAGNIILILPIILVYIFANKKV
                     KEAFMYSGIK"
     gene            complement(112566..113435)
                     /locus_tag="PC494_000097"
     CDS             complement(112566..113435)
                     /locus_tag="PC494_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HDF3910631.1"
                     /translation="MKKQFNKAYLYITPAIIGTLLFIVYPIIKTISLSFKSGSLLSST
                     FENVGLNNYTELLKNPEFIQTITNTAIYTFFMVTISISLAIVLAVWLNKNSIIHNLTQ
                     SIIFTPHVISLVSVAVLWLWIMEPQYGFLNWILSTLHLPTSKWLSSESSALMSLILIG
                     IWKTLGYNILIVLSGLKSIPNYIYEASKLDNANKITNFFKVTLPLLSPTIFFLMITTT
                     TASFQVFDEISIMTQGGPVGSTNMLSYYIYESGFIYYDIGQASAASMFLLAIVMIATY
                     ANFRLLSKKVHYQ"
     gene            complement(113419..114489)
                     /locus_tag="PC494_000098"
     CDS             complement(113419..114489)
                     /locus_tag="PC494_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF3910632.1"
                     /translation="MADIRLENVTKSYNKKNTVIENLNLTIEDGSFTVLVGPSGCGKS
                     TTLRMIAGLEDITSGRLKIEENDVTKTDASKRDIAMVFQNYALYPHMTVRENIEFGLK
                     NKKVEKEKREKLITEVIDVVGLREYLNVKPGNLSGGQRQRVALARAMVKNPKVFLMDE
                     PLSNLDAKLRNQMRTELIQLHQKLKSTFVYVTHDQVEAMSMADKIVIMNKGKIMQIGS
                     PKKIYQNPKNLFVAQFIGSPCMNILDIKNDIKFGFRPEKATLESINIDGKNDDVFSLF
                     GKVVTKEVLGNETIYCLSVLNREIRVKTENDIFDIGRTLRISVLEKDLYYFDKNGERI
                     EDVKVCKSMYSKIKGDIYEKAI"
BASE COUNT        36690 a        19888 c        13126 g        45237 t
ORIGIN      
        1 acaatacatc attttaatta atttagatgt atatactata aaaattaaat aaaaatagag
       61 actacacttt accatgtagt ctctatcttt ctggtcatat ttagaaattc acatttattg
      121 ttactgcttt tccgcctcta tttactgtta tttttgtact agcacctttt gagaaagtat
      181 acaacttttt atttaaatca ttcatacctg ttatatctgt atctcctact ttagttataa
      241 tatcccctac ctttactcca gctttttctg ctgatgaacc agatattact tctgcaacat
      301 aaacaccttt atcagtactt aattttgtac ctgttgctgc ttcataattt gatacatctg
      361 taccttttat gcctaaagtt actttttcat attttccatt tttgattact tcttcaacta
      421 tactcttagc tgtattgatt ggtattgcaa atcctaatcc ttctgcttga gaagcttttg
      481 ctgtgtttat accaattact tgaccttttt gatttaacaa tggtcctcca ctatttcctg
      541 catttatact tgcatcagtt tgtaataaac cagtcatatt agttttttct gtttgtatag
      601 ttctatctaa tccacttatt atcccttgag taactgtttt ttgaaaatct aatccaagag
      661 gattacctat tgctattgat atatctccaa cttttacttt gtcactatca gcaaattctg
      721 ctggtgttag tccagtttta tcaaccttaa ctatagctaa atcaagttgt tggtcaaacc
      781 atactacttt acctgaagtt gttgaaccat cattgaataa tacatttaca ctcgtagctt
      841 gaccatctga tataacatga gaattagtaa gtatatatcc atttgaatca actatgattc
      901 cagttcctac accttgtgtt tcagttggta ttgcaaacat attactagta tcaacactag
      961 ttgttgtaat acctacaaca gatggcgtag ctttttctgc aactgcttga taaatatttt
     1021 gactcttacc atcatcattt acaactatcg gcgtagaact tcctgtagat ttgcttacta
     1081 aattgtcctt aactaaaatt attgttagaa aactactaag tattgaactt attatagcaa
     1141 ctaatattac taaacttatc cctttctttc ttcttgacat ctcataccac tccctatctt
     1201 aatataatat aaattatcaa aatatatttt tcccaatttt tcataaaaaa aatgaaatca
     1261 tctattttga gtaaactcct ttttgatgat ttcattatat tattttaatc ttaattaaac
     1321 cttaactatt taaaattatt taagtctttt ttctagctct tccttttctt tttcataacc
     1381 tggtttgcct agtaaagcaa acatattttt cttgtaagct tctactcctg gttggtcaaa
     1441 tggattaact cccaataaat atccacttat tccacaagcc ttctcaaaga aataaactaa
     1501 atatccaaaa ttatactcat ctagttgagg tatatttatt actaaattag gtacttttcc
     1561 atctgtatga gccaatagag ttccttcaaa agctttatga tttacaaaat ctacagtctt
     1621 acctgctaaa tagtttaaac catctaagtc tacttcctct gaacttatag ttatatttct
     1681 cttacagttt tcaacattaa gtactgtctc aaataaaagc ctttttccat cttgtatgta
     1741 ttgacccata gaatgtaaat ctgttgagaa atctacagaa gcagggaata aacctttatt
     1801 ttcttttcct tcactttctc cataaagctg tttccaccac tcacttacat aatgtagttg
     1861 aggttcatag ttcactaata actctacatc ttttcctttt ctatgtaaaa ttgttctagc
     1921 aacagcatat ctataactat cattactttt taagtcagga ttttgaaatg cttctctagc
     1981 atcatttgcg cctttcatca tagcatcaat atcaagtcca gcagcagcaa taggaagtaa
     2041 cccaactgct gtcaatacag aaaaacgacc acctacatca tctggtatta caaaagtctc
     2101 atatccttct tctgtagcta actgtctaag tgcaccttta cttgcatctg ttgttgcata
     2161 aattctcttt cttgcttctt ccttaccata ctttttctct aagtaatctt taaatattct
     2221 aaaagccaga gctggttctg tagtagttcc tgatttagat attacattta cagaaatatc
     2281 ctttccttca attatatcta ataaatccat aatatatgtt gagcttatat tatgccctac
     2341 aaaatatact tctggagcct ttctttgctc ttttttaagt ccattcctaa aagaatgact
     2401 taccatatct atagcagctc tcgaacctaa ataagagcct cctataccta ttaccaaaag
     2461 aacatctgag tctgatttta tcttctcagc agattttttt attctgtcaa actcttcttt
     2521 atcataattt ttaggaaggt ctatccatcc taaaaaagta tttcctaaac cagttttatt
     2581 atgtaacatg tcgtgcgcaa catctacata tggttgcatg acatctattt cgttttgaca
     2641 aaaaaactct gtagctttac tataatcaaa atttattttt cccatttaaa tccctctttt
     2701 cagcatattc gttttaaaga gattataaca caaaatatag gtgttttttt taaaagtttg
     2761 ccacaaaatc atacatatct catcatttat tatcaggaaa tcgattcttc taaatgctat
     2821 aactatgtat aaatttaaaa attttagtca aataaattta caaaaaaaga aactctaaac
     2881 gtatcattta aagtttctct tttatttatc ctctatttta aattttatat tattttaaat
     2941 taattatttt taatcatttc ctaatctctt tgctataact tgttgtgcta tattgacagc
     3001 atggtcagat attctctcta aattacttat tacgtctaaa taaataactc cattttctat
     3061 actacataga ttattgttca atctatacat gtgattagct ctacaagatt tctccattat
     3121 atcaacttgt tcttcaattt ttataacctt acaagctaaa tcaacattat cagttctcat
     3181 tgattctaat gcataagtat atgctgaaac aactctatta tacataacat caagttcaga
     3241 ttgtccttct tctgagaaag aaatatttga atctattgca acttgcgata attcagctat
     3301 atttttagcg tggtcaccaa ttctttctat atcattgact gtattaaaca aagtatccac
     3361 aacttctctt gaatcatcac ctaaaggtgc ttttgaaagt ttaagtaaat aatttaaaat
     3421 agctttctgt aaatcattga ttaatctctc tcgcctatat gtcttatcta ttttttcagt
     3481 tgaatgttct actaaagctt ccatagatgc atttaggctt tccttcgcct tctcacccat
     3541 acgaagtgct tcttttatcg tatttgcaag agctatagaa ggagtttcta tcattctatc
     3601 atctatatat ttaatagttt tagtttcatc ttcatctata tcacctgctc tatcaggaac
     3661 aagctttata gctagtttta taataagatt tgtaaatggt aaaagtatca atacagatat
     3721 tatattaaac aatgtatgtg tattggctat ttgtcttgca acattgcttg ggtcccaact
     3781 tgtaaccatg cttactactg gtttattcaa gaatattaag aatatcactg ttcctaaaac
     3841 attgaagatt agatgcatca tagctgctct tcgtgcattt ttgttagcac caatacttga
     3901 taacagtgaa gttacacatg taccaatatt ttggccataa agaattggca gtgctgctga
     3961 taatggcact agaccttctg ctgccagtgc aaccaacata cccatagatg cacttgaact
     4021 ttgtattatt gctgtaatcc caaatcccaa taataatcca agtagtggat atctaccaaa
     4081 tgtaacaagt aagtcagtaa atccttgata gtctcttagt ggctccactg ccatcttcat
     4141 aaaatccata cctgtaaata atataccaaa acctataagt atttcggcta tattttttat
     4201 tctaggctta tttccaaata aataaagtat aatacctaca cctaatgcta ctggggccat
     4261 accagttaag tcgaaagata ccaattgggc tgtaacagta gtccctatat tagcacccat
     4321 tataactcct attgcctgtt ttaaagtcat tattcctgca tttacgaaac caacaaccat
     4381 tacagtagta gcacttgaac tttgtattac tgctgtaact cctgtaccta ccaaaactcc
     4441 cataaatagg ttactagtaa gtagttttat tatctttttt agctttgtcc cagcagattt
     4501 ttgaagacct tctcccataa ggttcatacc atataagaac agacctaatc cacccattag
     4561 acttattata atgttcaaat tatttcctcc ttgtaaagag attactgtat ctaaaaattt
     4621 tataacctat tgtattttat caaattatag gagtgataat gttaaattca tgttaaatat
     4681 taaaaaatca ttaagtttat gttaaatttt tgtattattg gtgtattttt gtattatttt
     4741 ttctgcacat tttataccat caactgctgc tgtaactata ccacctgcat atccagcacc
     4801 ttcaccacat ggatatagat tcttaatact cactgattct aaagtatttt catctcttac
     4861 tattcttatt ggtgatgatg acctagtttc tactcccgtc aaaacagcat catacattgc
     4921 aaacccattc aattttttat caagagatat aaacgcttct ctcatagtct ctgttacgaa
     4981 gctaggcaaa cattcactta aatttgtaag tgtatatcct ggtctatatg atggctcaac
     5041 acttcctaaa ttcaaagaag tcttattgtt tataaaatct ccaacaagct gaactggtgc
     5101 attataattt tttccaccta attcaaaagc taatttttca tacttctgct ggaaatgaac
     5161 acctgctagt gaattatcac tcttaaaatc ttctggcgtt acatttacta aaaatgcact
     5221 atttgcattt attttatctc ttgcatgttc actcatacca tttgtaacta tttcaaaatc
     5281 atttgatgca gatgctatga cactacctcc tggacacata caaaaagtat atgctgttct
     5341 tccatttgaa acatgctcta taagtctata atctgcagct cctaacctag gatgattata
     5401 aaaatccttg tactgtgctt tatttattaa atcttgtgga tgttcaactc tagctcctat
     5461 tgcaaaaggt ttttgaacta tttttatacc tcttgaatac aacatttcat aagtatctct
     5521 tgcactatgt ccaacagcta atataattgt atctgtatct attttttcag tatcatttat
     5581 tattacagat tgtatagaat catttgatac aactatatct gttacttttg aattaaatct
     5641 aacttgacca cctaaactta ttatttcatt tcttatattt ttaactacat tttttaatat
     5701 atctgttcca acatgtggct tatgtgagta taatatttca tctggtgctc caaactgaac
     5761 taactcttct aatacttttc tacatcgtat atcttttatt ctagttgtaa gtttaccatc
     5821 cgaaaaagtt cctgctccac cttctccaaa ttgaacgttt gaattatttt ttaattttct
     5881 agttgtccaa aaatcactta tatctttggt tctactgtct acatcaagac ctctttcaag
     5941 tatgattggt tcataaccca tttgagctaa aagcagacct gcaaacaaac cagctggtcc
     6001 actaccaatt accaaaggat tattctttaa ttttttatca cccacaggta catttacgta
     6061 tctgatttcc tttatttttg ttacatcttt tatttttgag ttaagtattt tattttcatc
     6121 tttaacttct acatctacag aataaacaaa ttccattttt cctttttttc tagcatctat
     6181 agattcttta tatatactat atttgactaa gtttttttct tttattttta gcttcttaag
     6241 tataacatct tttaataaag atatatcttt atcaattcca agttttacat tagatactct
     6301 taacatattg ttttcctctc ttagattgta atataaaaaa gctagggtta ttcctagctt
     6361 tctacaaata taacttctat attctctttt actagatttt ctacccaaat ctcatctagc
     6421 acaaaattct ttattttgtt tacaacaagt gttttatcta aatctttttt caagtttttt
     6481 actaagacca ttgcttcaac tgatttatgc aatctttcaa catacagaga attaacttta
     6541 atcaatacaa ccctcaattc acatacatat aacttttcac tacctaaggt gatttcatca
     6601 tcatattcat atacactaaa ttcatatgta ttttcataag gtgttatatt ttctattcct
     6661 atatagtcca tttatttatc cttttttagt tataagacct cttataacct tcatattatt
     6721 aaacaccttt tctaagaagt tctctgcttc ttcattgtct aaaaggttta tttcaaggtt
     6781 ttcgttttct acaatacctt tagatttaca gtactcttta gcaatattta ttagttcatt
     6841 ttttttatcc atagataaat caaactcttt atagtctatt attatatatt gtttggtatc
     6901 aggtgataca ccattattat atcctatttc tatatgataa ataactgcat atatttcttc
     6961 tccgttgtac acaggtacag ctgggttaga ttttataaag ttcgttgata cagcaattgc
     7021 atttcctaaa ctaagactca ttattaatac ctctttctaa acattataca tatattatac
     7081 tatagattct ttatctatga cttaaagctt tttataatta attaagatat ttttaaatcc
     7141 ttgtatctct ttcctagtgt actagagctt atatcgtatt tctttgatat ttgaacttga
     7201 gttataggtt gtcctgcttc ttttttaaca tagtattcaa cagcagctgc ccaaccattt
     7261 tcagctcctt ttatattttc atgatttttc ttatattcat tccaaaactc tatacatgca
     7321 tctatatttt ctttttctac attttcttta agagtatcta aaactttaca ttcttcttca
     7381 gctaattcat tttctgaatt aacttttgta tcgtttttat ctctttctct ctttaaatat
     7441 tcagctatac ttgggtctaa aagctgttgt atatacttgt atagtatatg tgtatgataa
     7501 attaagaacg acttcatatc tttgtataca tcttgatatt gattgaatag attcataata
     7561 tcctttaaaa ttatatcttt aacctcattt gatatactta tagttatatc tatcaatatg
     7621 ttagttcctt caatatcaac tattctagct atcatacaac ttccgatttt aaaacttctc
     7681 agaagtttta catcttctgt acaaagttca tttccactta aacagtcctt taatactatt
     7741 tttccagcag aaacttcttt tacctcataa atacttacgt atgattcaaa catacttttt
     7801 aatattgata cttctgattg acttaggttt gtaccatttt cttcaagaaa accaactgtc
     7861 ataacctttt tattttccat tatgtggtct tgtattaaat aagtattaaa aaatctttca
     7921 aatttttcat ttacactatc attttgcatt atataaaaca tttctttagc tttttcacat
     7981 tcttctttaa acttatcctg tcttgaataa tcatataact ttgaatataa atctgtatat
     8041 tgtttttgtg aaagttcagt ttttctgcat gctctttctg aaacaatatc tttatttaaa
     8101 caacatttct tgtatttttt gccacttcca caagggcata gctcatttct ccctaacaat
     8161 atgacttcca ctcccttatt attaaattaa agtacaattt gttattatac cattttttta
     8221 ttaatcaatc tatagtataa gtaaatattc tattaaattc acttatattt tggtacaata
     8281 tattaacttt aattaggatt tcgataaaat catcaacaat ccctcttgta gaaatgaatt
     8341 atcgtaaaac taattcctct ataaaatttt attaattgat aatagttttt tactttatct
     8401 attctttttt gttatatgac tctaactgtc attttacatt caacaatatt gtctttttct
     8461 tgtttatatt catttggaat attttgaaca tcaaaattat tgacttttaa tttattaatt
     8521 tctatctttt caagtttatt atttagtctt aacttcttca ttacaccttc aagtttcaac
     8581 acatttgcaa gttctccatt aacttttatt tctaaattaa cttgtttttt attgtgatta
     8641 tctaaactac tttcttgatt aatatattct acattcacaa tatctctcag ttcattttct
     8701 actaataaca ctatatcttt atttgttttt ttatctaaaa atgagttatt aaaattattt
     8761 ttcaattctt catttttatt tgattcaaca ctttctatat atttatcatc tatatgttta
     8821 ttatccttta tttgataatt atcttgatta tttattttat ttattatatt ttgcttttca
     8881 tttttcaaac tagttaggtt ttcttccaaa taacttactg ctatatcact tgccaatata
     8941 ataactaata ttaacaatat tttaagtaga tttttttctc tattatttaa tctcaaaaat
     9001 aatcacccat ctaacttttt attctaaatc tataatattc tccatctctt acaatactgt
     9061 ctatgtaata atattttatg tactttattt tccttaggtt gtttaaaaca tctaaatcac
     9121 tacacacacc ttccatctct agcttatttt tatctatcga tattttagta atactattta
     9181 ttccaattgt ttcatatatt ttttttattt cattaagttt tattttagaa aatttctctc
     9241 tagttttatc tgttgttggt aaagtattct ttgatttatc cactagctta ttttgactta
     9301 tataatcttc aagttcattt atagatttca catacataaa tgatttaaat aaaatacacg
     9361 ttaaaattaa gactattatt attttataga ttttattaca tggtttagtt tttttaaatc
     9421 cattaagaaa atttattgtt ttatccactt tcacttaaat aatcattcct atattactta
     9481 tataatttat cctattgtct tctaaatctg catcaaaatt attttctact tttactttat
     9541 cttttaatct taatggattt acttcaatag atttatctgt atatttaaag tattcttcaa
     9601 taaaacaatt ttctatacca tagtaataaa catacttaaa atcccttaat aatcttttta
     9661 tgaactcata tgattttccc tcttttgata gcaagtatgt ttctcttatt tttttatctt
     9721 ttgttatatt tataattaac tgactttttt tacattctat aaatacccct tcttctgaaa
     9781 aattctctat taaatttaag tttataagct tttgtaatat atcaaaattt atatttatag
     9841 tctttggatt catatttaga ttttctgaaa tgttcttaat taattgaata atactctttg
     9901 ggaaaagaat tacttgtata ttcaatttat catttttaga atttataact ttatatttta
     9961 ttgaatagtt atttatgttt attggaatgt attgtgttat ttcaaattca atcatgctta
    10021 atatgtctct ttttttctta gtatttagaa cttcaacatt tctaatgact atatcctgaa
    10081 tttgaatgtt aaagtataaa tttttatata atatttttga tttaccaatc tcctctttta
    10141 caaatctaac tacatcttct atatacttaa tcttctcaat cgaattacta tcatttttta
    10201 tatcaaagtt aatctctttt ataattgatt tatctataaa aactttttta tgaccttttc
    10261 ttaaaaatac aagccttata taatcatcat ttatttctaa gtttagaatt tttttaatta
    10321 tagccatctc cttcttaaat aaaaataatt ttaaaactta cagcaatcaa tataaaatat
    10381 tattttggat aaaattgctt agaatttata tttacgctta tatctgttcc gctatcattt
    10441 atgacaagtt cgaatttacc tgatgtactc tgaggaactg gaacagtatt taggtatccc
    10501 ttttccttca atgtctctac acttagagag tctattgtct tttcatcatc attaattgcc
    10561 atgctagctg cggttactat attagcagca ttcgtatagt ctgcatttaa tttggcactt
    10621 tcttgaacct tactatactt aactaatgct atactagata taacgcctaa aatagttact
    10681 actacaatca tttcaacaag tgtaaatcct tttcgttttt tatttatcaa atttatcaat
    10741 taaatattct ctccttttca aaagtttcat ctaataaaat ttatttttct ctctaaaaat
    10801 tagtaattgc atcaaacata ggaacaacca ttgctaaaat aaaagtacca ataattaatc
    10861 ccataaatac aattagcata ggttctataa atttcattat ttgctctatt ttgttattta
    10921 attcattttc ataaaattta tttattacat ttagactttt atctagtttc ccactttctt
    10981 ctcctatatt tgccattgaa ataaataatt ttggaaaaac atttgctaaa ttcaaagatt
    11041 tacctatgct atttcctttt tttatataat tattggaaat ctttaacctt tcataaataa
    11101 attcgttgtc tataacacta gctgacatgt ctatagcttc cacaatttgt attccactgc
    11161 taattaaaac ggacaatgcc cttgaaaatc ttgttgtagc tactaactga ttaatttttt
    11221 ttataaaagg tattttgaat tttaacgaat taatcaattt ttttatatta tcatttgtta
    11281 taaagaaata aatgcttcct attgaaaaca atataaaact aaatattata taagctaagt
    11341 tatttgtaac cactgtagat attcccatta aaactctagt tattaaaggt ggttcaattc
    11401 cattgttggt aaaaaccacc tgaaaattag gtattacaaa tacgaatata aacaacattg
    11461 ataagataga taatattata agtattattg gatatattga aatagttatt attttcattt
    11521 ttaatttgta ttctttatca taataattag ataaatcact cattattata tctaagtttc
    11581 cactagtttc tcctgctttt atcatactta taaagaattt agaaaatata cctgttattt
    11641 gaaatgattc tgctattgag ttaccttttt gaatatgatt tgatactata ctaagcaaat
    11701 tctttgcttt tttacttgac tgactctcaa tgatctcaaa tatttttgta atttcacatc
    11761 cagattccag caatatgcct atctctttgc aaattactct aatttcttta tcactgattc
    11821 tatttaatac taaataaaac ttttctaaat tataaaatat atttttagat aatctcatgt
    11881 actataatac cttccaaatt atattaatta caattaaata aacttaatat tttctaattt
    11941 aatgcattta attttatttc acttaaatat aatttatact caaacatctt aattaaaata
    12001 gattaaataa agacaactga ccaaacgaag tttaactata caattcagtt aaatcatttc
    12061 atttactact aaacactctt ctaatgtcgt tattttttca tttattagtc ttttacaact
    12121 atcttcaaat gttatcattc cattattttg tgccacatct ttaatagtac tagaatcctc
    12181 catatttctt atacatgtct ttatatcatc attaatttct aagatttcat aaattgctgt
    12241 tcttccaaag tatcctttat cattacattt ttcacaccct acagctacct tagtatttac
    12301 atctccacta aaattatctt ttatcataat ctcatggcta caatgattgc agacttttct
    12361 aaccaacttt tgagatataa cacctataag agaggcattt aaaagatatg gtggtatttg
    12421 catttctagt aatctagcta tggaagatac tgcatcatta gtatgtaaag tacttataac
    12481 taaatgacct gttatagctg ctcttactgc tatcttagct gtttctgcat ctcttatttc
    12541 tccgaccatt attatatctg ggtcttgtct taatatcgct ctaagaccta catcaaagct
    12601 caaccctact tttgaattta cttgaatctg acttatgcca tccatcttat actctacagg
    12661 attttctata gtcataatat ttttatttat tccttttaaa tcatttaata aggaatatac
    12721 tgttgtagtc tttccactac ctgtaggacc tgtcactaat aatattcctg ctcttttatt
    12781 tattatacga tttatagatt ttatagcttc ctctgaaaaa ccaagttcta atttgtcttt
    12841 taaaaaagta tctctattaa gtatcctcaa aactattttt tcaccataga cagttggtat
    12901 tgatgaaact ctaatgtcaa ttaaatttcc acctaacttt atatccaccc taccatcctg
    12961 aggaagcctt ttttctgtta tatccattga tgcctttaat tttataaccg tagacaatga
    13021 tggatagaca tcaactaaaa actttgatac ttcctttagt tctccatcta ccctcattct
    13081 cactattaaa tgttctttaa atggttctat atgtatatca cttgcgtttt cttttatagc
    13141 tttttctaaa agattttcaa ataatttttt tgcataatcc tcatcaagtt caaagctatt
    13201 ataatatttt tcaatctttt cacttataag ttcttttttc tccttcttca atataatttc
    13261 tttacctgta gctaatctca agtcctgtag agcataaata tcctcatctt ctatttctac
    13321 aactaaatta tcatcttgaa actcaactgg aaatacatta tatttttttg caagtttttc
    13381 tggtattaac attggcaaac tgctttcctc taatataatc ttaatcaccc tttatatact
    13441 ttaatttatt aggtatattc atttttttca tagagatatt ttcttcagtt tttatgctta
    13501 ttttcattgg ataattggtt tgtatgctat ctaaatattt actaccttta tctacataat
    13561 tagatagttt ctccttatct ccaatgcact ttatttcata tggttgtgct acaggaactc
    13621 catttatatt tatatggctt cctgcaagta caacttctga atattgatta attctttgac
    13681 catttatttc tatgtatttt cctccgttta cttttaattc atttataact tttacaagaa
    13741 tcttattata gtctatacta ttagctatat tccctgtttt ttcatctata gcatctatac
    13801 ttaatattat cccactaccc tttacatctg aatatgatag actatctcta agtgtttcta
    13861 tttctgatat ttcttcagaa tttttttgat tttgtttcat tgaattaatt tctttatcta
    13921 acttgtcttt ctctttggtt aattctttta tagattttct tgtcattttt atttcttttc
    13981 ttattgactt gtctttgctt gtataaactg tttcttcatt gctataatct ctaaatatgg
    14041 ttccaacaag tatacctaaa atagtacttg ttagtattat aaacacatat tgttttttca
    14101 tactgtattg ctccttacaa atttattttt atatgataat tttctttaat taaatattaa
    14161 acatttacat atgcttatta tatcaaagtt atatattaaa attcatcttt agtatataat
    14221 atcatacatt gaactcctat cactaattta ccaatatcaa gtatgcattt ttagatgttc
    14281 ttaaaattat ataaactttc aataaacatt gttttgatat tataaaaaaa tataaattag
    14341 gaaaggaaat aataattatg aaaaacaaat aattgctttg gagattatta atatcatttt
    14401 ttagcaaaaa aaagtaaaat ggcatagcct caaagctaca ccaatttact aaaaattata
    14461 tcattattaa cattaatttt aaacatatac gtttataagt tttcctcata ttttaaaatt
    14521 cttttaatta atttatctct taatttccct acttcatcaa atctcatatt aggactatag
    14581 taactttcta taatatcatg tttagacttg gctctcttaa gatttagtac tgcccaacaa
    14641 attaaatcat ctaaaacttt ttcatcaaat ttaatatctt cttcatattt aagtagtttt
    14701 tctctattta aaaactgatt taaatcaatt gtatcttctt ctttaaaagt cgtacttata
    14761 gttataccta tgtctaaatc agttaatagt acagtttcaa ttttctctgg aataagtgga
    14821 taatgataaa cttctacatt taaacctttt tcaatagctt tcttatatac tttgtttaat
    14881 aatgtagttt tcccagttcc tatttctcca tctaaataat agactttctt tacatctttt
    14941 aaaatgtttt ctgtataatc taaacaccct acaggagtta tagctgaacc aaataaatgc
    15001 ttttctcttt ttagatttcc tgtgctttta actccatcaa ataacctttt tataaattct
    15061 tctgtgacca aatttacttt gccataatcc atacaatcag aatatttttc ttctatgtct
    15121 ctaaagattg gttctgctga ttttaaaaac ttaaatgctc ttttaaatga attactaata
    15181 tctttatcat aaactgatat ttcttgttta ttcttttcta attcttctgt attccagtaa
    15241 tcacctaaat taattatctc atccaaagct ccaggtagct ttgggtccat agtatgtggg
    15301 gcagttgcat ccataagtac cacgcctaat ttctttataa ctaaaccatc caacgaactt
    15361 gggtcagaag gacaatgata taaatcaata tcatatcctc tatgcaaaaa ctctttataa
    15421 atttttttca taagtgagga ttttcctact ccaggtccac cctttaaaca aaaaactctt
    15481 tttacatttt caggaattat atagtcaaaa aaagaatatg agccttgtga tgtatttcca
    15541 cccgggaatg ccttctttac ctttccttcc atattagcgc ctcctcataa tttacaatat
    15601 ctcttaatta agatattcat attataagaa ttttattaca gctttcttat tttgacaaat
    15661 ttaaaacttg ccatctaata ctaataacag gttaatttta tctaattatt atagattctc
    15721 atactgtgcc ttattctatc tataaataca atttaagtgt ccatattgaa atatttgtat
    15781 tgtaatacag ctggatatta cttaaatcca attgtttcca ttataatttt atgttaaaat
    15841 aatattacaa aatacatctg tttttcttca taaacgggtg aaattcccta tcggcggtaa
    15901 aagcccgcga gccttatggc ataatttggt catattccaa agccaacagt aaaatctgga
    15961 tggtagaaga aaatagtata tgagtacctt tatgtaattt tacatgagta atctatacaa
    16021 atccttcaac taccgtattt attcatgaaa ttagacacat tcaaggtacc taatatacag
    16081 gtgctttttt tgttgtttat tttacaatta tatcgtactt ataaaatcta ttaagattgg
    16141 agtgttatca tgaaacaaaa atggatagta ttgattatca tctgtattgg tgtatttatg
    16201 tctactcttg atggaagtat actaaatatc gcaaatccta caattgctgc tgactttaaa
    16261 attaacatgt cacaaattca gtgggttgta acagcttata tgcttgttgt aacagctact
    16321 atgttatttt tcggaaaact tggcgataaa gtaggttcaa atcgtctata cacattagga
    16381 ttttttatat ttacaatagg ttcttttctg tgtagtatgt caaacaattt atcaacatta
    16441 atttcttcaa gaatctttca ggcagttgga gcaagtattt taatggctac tgggcttggt
    16501 atagtttcca atgcatttcc agcaaatgaa aaaggaaaag ctataggaat cactggagct
    16561 gtagttggta taggaaatat gagtggtcct gtaattggag gtataatttt agaacatttt
    16621 ggatggcctt ctatttttat tatcaatatc cctattggta ttatagcagt ctttcttggc
    16681 attaaatttc tgcctaaacc tgttttggat gaacaaaaca agagctttga tattccaggt
    16741 cttctacttt tcgcatcttg cactacgctt atattacttg caatgaatga gaagggtaat
    16801 acaagattgt atttaggtat aacagcactt ataatcttct tattgttggc attaagagaa
    16861 gtaaaatttg aacaaagctt tattgaccta cctctattta aaaatagaaa ctttactgta
    16921 ggcaatatca ttggagtagc ttgttatttt cctcaaatgg cagtatcttt tctacttcca
    16981 ttttatttag aacaattaaa aaatttatct cctatgatgg ctggttatgt aatgactgta
    17041 catccactta ttatggtact tatagcacct attgcaggtt cactttctga taaacacggt
    17101 gcaaaaaaca ttctaacagc atctttttca tttatgacca tctcactagt tggaatggca
    17161 cttttaaaag cagattctcc attgtatctt ttaattgtat gtttagttat ttttggactt
    17221 gggctaggag catttagttc accaaacaat agtagtattt tagcagatgt tcctcctcaa
    17281 aaacagggat acggaggcag ttttcttgca actattcgta atttatcatt tgctcttgga
    17341 acagcatttt ttagtagttt ttttgcacaa agtcttacat acaatcaaaa gtttaaaagt
    17401 cacacatcag cctatgttat agctagcaat cagtcttatt ggattgcagc atcagtatgt
    17461 tttatagggc ttatactaac tgttttcttt atgagaaaaa cagataaatc tatttcttaa
    17521 atgctattta ttgctgacta cataagtcaa taatttttta gttgaactaa tttatactaa
    17581 ttttcccata ccttactaaa atttattagt atttagcaaa attactgata tttattgttt
    17641 ataaacaata aggatgccaa aaaaagttca ttaaaactat tttaaggcat cctatatttt
    17701 gctttaatat taatataatt aaaactaact attattacat ttattattca aataaatctt
    17761 atgtcaatat ttaacatttt aaatttaatc tactgttatt tcatatccat gttgattgta
    17821 ttgatttaca atctcttccc ataattcttc aacaccagtc ttttttagtg aagaaacagg
    17881 aattactttt tcactacttt ccatttgcaa tttttttctt attatactta tgtgtttttg
    17941 atattgtcct ctagatattt tatctgcctt agttgcaata actacacagt tatatccaaa
    18001 gtgctttatc cattcataca taagcttatc atctgctgta ggctcatgtc taatatctac
    18061 aagtaggaat atagaacata actcttgtct actttctaga tatcgttcca ttatacctcc
    18121 ccacttttct ttttcagact tagctatctt tgcatatcca tagcctggaa ggtctacaaa
    18181 ataaaattca ttatttatta gataaaaatt tatagttcta gtttttcctg gtgtttgact
    18241 ggttctagca aagtttcttc tgttaagcaa tgtatttatt attgatgatt ttccaacatt
    18301 tgacctacca gccaatgcta tctctgggat tccttctgct ggatactgtg atttattcac
    18361 agcactcata gttatctctg aacttctaat tttcattatt ttcaccactc tttaataaag
    18421 cttgttctaa tacttcatcc atatgttcta caagtacaaa ctccattttt tcttttacat
    18481 tttctggtat ttcatctaaa tcagcttcac attctttagg aattaatact tttgttatac
    18541 cagctctatg agctgctaat aacttttctt taactcctcc tactgctaag actctacctc
    18601 ttaaagttat ctctcctgtc attgctatat ttccaggcac aggtctttta gtaagtgctg
    18661 agattactgc aagagccata gttataccag ctgatggtcc atcttttgga acagcacctt
    18721 ctggaatgtg tatatgaata tcattcgtct tataaaattc agggtctata tcaaacttgt
    18781 ccactattga ccttatataa gagatacctg tcttcgcaga ttccttcata acatctccta
    18841 attttccagt taatacaatt tcgcctttac ctttaagtac gtttacttct acttcaagtg
    18901 taactccacc aacttctgtc cacgcaagac catttactaa tcctatttga gggttaactt
    18961 ctgcaagttg atacttaaac atgtcttttc caagatatgt ctctaggtca gacttattta
    19021 taacaacctc ttcaagagtt gggtcttcaa cgtatttttt ggcaaccttt ctacaaatct
    19081 taccaatagt tctttctagt gttcttacac ctgcttctct tgtataatgg ttgattatac
    19141 ttcttaaagt ttcatcatct atttttataa agttttcttt taaagcatgt tctttaatct
    19201 gttttggaag taggtatttt tttgctatat ttaatttttc ttcttctata tatccagata
    19261 cttctattac ttccattcta tctaataatg gtcttggtat attacctaga ctatttgctg
    19321 ttgtaacaaa tagtattttt gataaatcaa aaggtatttc taagtaatgg tccacaaaat
    19381 ccttattttg ctctgggtct aatacttcta gcattgctga agctgggtca cctttataat
    19441 ctgctgccat cttatctatc tcatcaaata agaatacagg attttttgtt tgggcttctt
    19501 ttaccccatt aattattctt cctggaattg aacctacata agttcttcta tgacctctta
    19561 tttctgcttc atctctaact ccacccaaag atattcttac aaattttcta tttaatgctc
    19621 tggcgattga ttttactata gatgtctttc ctgttcctgg aggaccaact agacatatta
    19681 taggcccttt aagtgactta gcaagagttc ttatagctag atactctagt attctctcct
    19741 taactttttc taatccataa tggtcttcat ctaatatatc ttttgcctta gttatatcta
    19801 atttatcttt tgtctcttta ttccatggca atgagaatat agtatctaaa tagtttctac
    19861 ttacagatac atctggagac atagaagata tttttgaaaa tttatctatc tctttttcta
    19921 ttttctcttt agttgtctta ggtgctttta tttttttaag cttttctcta tactcatctg
    19981 cttcagagtt tatatcttct tcttcaccta attctttctg tatagctttt aattgttctc
    20041 taagataata ttctttttga accttattca tctgtttttt tactcttaaa gttattttct
    20101 tttctatttt taatatatct atttcctcta ataatataga ataaataagt tcaagtcttt
    20161 ttctaatatc aaattcttct aatatttctt gtttttggct tgattttaga tatatgtttg
    20221 cagctatcgt atctataaat ctatctacat cttctatatc agctaaagat attaatattt
    20281 ctggtgatac cctatttcca atatttatat actcttcaaa ggcatcaaat acatttctta
    20341 caaatgcttc aatttcaact tctgtttcac tatccaaatt atcactatca aatactattt
    20401 cttctattac tgctctgaaa tacccatctt cttgttctat tttctttact ctaccccttg
    20461 atacaccttc aaccaaaaca cgaactgtat ctcctggtaa ttttatcatt tgcttaactt
    20521 tacagattgt tcccacatga taaaaatcct cttctcctgg ctcatctacc tctgcttctt
    20581 tctgagaagt taaaaatata agttcttcat ccatcatagc ttggtctaaa gctttaagag
    20641 atatctctct acctatatca aaatttaata tcatatatgg aaatatagct aatcctctta
    20701 gaggaattaa tggtaattca tgatctattt tagtataatt ttgttccatc aacattactc
    20761 cttttctagt ctaattgctt tgcttttaat attatatatt tgaacaagtt aattttcaac
    20821 attaatgata aattcttaga atactatcat actatattat ctttttatta tgatataata
    20881 ttaatattag tatacttaga tgttatttat cttttggagg tttctattat gttgaaattg
    20941 tttttaacct ttttaaaaat tggtgcgttt acatttggtg gtggatacgc tatggttcct
    21001 cttatacaag atgaacttgt aaacaaacaa aaacttttag agcaggaaga atttattgat
    21061 tatttatcca tagctcaaag ttatcctgga gtactggcag ttaatatatc tgtattatta
    21121 ggatataaac tttatggtat accaggagtt cttatatgta ccttaggctc tgctttacca
    21181 tcattttgta tagtcttagt cttatcgtat ctatacttta aaaattcatc atctaaaatt
    21241 ttagatggat tttttaaagg agttgcgcct gttgtaatag ctcttatatt gtattctttt
    21301 acgagcatgt tcaagaaact accaaagtct aaaactaaca tactactatt aattatagca
    21361 gttttatctg ttggtgtatt caatataagc cctatttatt taataattgg aggaggtgta
    21421 tatagtctat gtcagaaata atactactct tcttaatatt ccttaaaata ggggcattta
    21481 gttttggtgg cggttatgcc atgctaccat ttatccagca agaatttata tctaaatatc
    21541 actttataac taatcaagag tttttggatt tacttgctat atcacaatct acaccaggtc
    21601 ctgtagcaat aaatagtgct acatttgtag gatttaagac tgctggcttc tttggttctc
    21661 tagctgcaac tattggtgtt acaatttttg cattaatagg tctaactatt atatcaaagt
    21721 tattttctaa atttaaaaat aataaaaagg tagaaaactt attgacagtt cttagaccaa
    21781 ttactctagg attcatatta tcagcagctt tttcatctgc caaagaagtt aattgggatt
    21841 tatatggaat aattgcattt atagcatcat tttatctttt atataaagga aaaattggtt
    21901 ccattgcaat tgtattcgtc tttggtattc taggtatatt actcacattt ttataataat
    21961 gatacctatt ttatatttag catattaaca taaaaaaagg agcttttaaa gctccttttc
    22021 atcatcttat gcactttcct cttgatcctt aagtactatg ataggattta ctgagtcttc
    22081 gttcacagat ttctctgtta ctataacctt ctttatatta tctctagatg gtacttcaaa
    22141 catagtttcc atcattacgc tttcaactat acttctaagt cctctagctc ctgtatttct
    22201 ttctatggcc tttttagcga ttgcacgaag agcaccttct tcaaattcta gctcaacatc
    22261 atctaactcc aataactttt tatactgttt tactagagca tttttaggtt cctgtaatat
    22321 ctgcattaat gcatcttcat ccaacaactc taaagtagct aaaactggta ttcttcctat
    22381 aaactctggt attataccat attttaataa atcctctgga agtacttttt catatagctt
    22441 ccctaaatct aattcttttt tactttctat tttagctcca aaacctagtg ttttatctcc
    22501 accacgtttt tgaattatct tctctaatcc atcaaaagct ccacctaata taaataatac
    22561 attagtagta tctatcttta aaaattcttg atgaggatgt tttcttcctc cttgtggtgg
    22621 aacatttgca acagtacctt ctaatatttt tagaagtgct tgttgaacac cttcaccact
    22681 aacatctcta gttatagatg ggttttcaga ttttcttgca atcttatcta tctcatctat
    22741 atatattata cctctttcag ctttttctat atcaaaatca gcagcttgaa taagttttaa
    22801 aagtatattt tcaacgtctt ctccaacata tccagcttca gtcaatgatg tagcatctgc
    22861 cattgcaaaa ggtacattta gagttcttgc tagagtttga gcaagtaatg tctttccaga
    22921 acctgtaggt cctaataaaa gtatattact cttttgaatt tctatatcct tactactaga
    22981 ttttttactg tatattctct tataatgatt ataaaccgca actgataaag cttttttagc
    23041 tttttcttga cctattacat aatcatttag aatctccatc atttcctttg gttttggtaa
    23101 agatgtagta tcctcatcta tagtatcttc tatctcttct tgaataattt cgtcacaaag
    23161 ttcaacacac tcgtcacaaa tatatacatt tggacctgca attaatcttc ttacttgatc
    23221 ttgattttta ccgcagaatg aacactttaa ttgtcgtttt tcttcatatt tagacatatt
    23281 aacacctctc tctatctacg gtctctttgt aaatacttca tctattaaac catattcttt
    23341 ggcttctagt gcactcatga agttatcacg ttcagtatcc attttaattt tttctaatgg
    23401 ctgaccagtt ctttcagata atatctcatt taaagtttct tttattttta aaattctctt
    23461 tgcatgaatt tctatatctg ttgcttgacc ttgagctcca cctaatggtt gatgtatcat
    23521 tatttcacta tttggtagtg ctagtctttt tccttttgct cctgctgcca acaagaatgc
    23581 tcccatagaa gcagccatac ctatacatat agtacttaca tctggtttga tgtattgcat
    23641 agtatcatat atagccattc cagaagttat acttcctcct ggagaattta tatataaatg
    23701 tatatctttg tctgggtctt cagcttctaa aaataatagc tgtgctacta taagccctgc
    23761 tgtggcatcg ttaacttgat ctcctaagaa gattattctg tcttttaata gtctagaaaa
    23821 aatatcataa gatctttctc ctcttcctgt ttgttcaaca actacaggta ctaatgccat
    23881 ggtttcatac cccctttatt ctatataatt tacagtagct ttttttaagc tactgtaaat
    23941 tattatacgc atttaactaa attatatttg cacatcatta tatactaaac atttcataac
    24001 gtcaactata ttagttagcg tttattttat taagctattg ttgcattatc aactaataaa
    24061 tctattgttt ttcttatttt tatttgacct tttatatctt ctttgtcagc atctcttaaa
    24121 gaagcttcta ttttttctac ttccatattg taagcagaag ccattttttc taactcagcc
    24181 ttaaattctt cttctgttgc ttcaattcct tcagctttag ttattgcttc taatactaaa
    24241 gaagacttaa ctaatttttt agcatcttct tttctctctt ctcttaattc ttccatagtt
    24301 ctaccagtca tctctagtaa ttgttgtaat ccaaatcctt gatattgtaa ttggtagtta
    24361 agttcattta acatattatc tatttgatgt tgtatcataa cttctggtat ttctatttct
    24421 gtattttcag caactttttc tactactgaa tttctagttt ctgcatctgc tctattttta
    24481 gcttcttctt ctaacttagc tcttacatct gcttttaatt catctaaaga atcaaattca
    24541 ctagtatctt tagcaaattc atcatcaagt gcagataatt cttttacttt tacatcattt
    24601 atttttacat taaatacaac tggttttcca gctaaatctt gtgagtgata ttcttctggg
    24661 aaagtaacat taacttctac ttcttcacca gcttttttac ctactaattg ttcttcaaat
    24721 cctggtataa atgtgtttga acctataact aagttataat tttcaccttt accaccatca
    24781 aaagctacac cattttcaaa accttcgaag tctattatag ctgtatctcc atcttctaaa
    24841 gctttgtctt ctacacttac taatctggca tttttttcaa ccatttcttg tagtttagca
    24901 tcaacatttt cgtcacttac agtattctca accttagcta tttctatacc cttgtagttt
    24961 cctaattcaa actctggttt aacttctaca ttaagaacca taaccaaccc attgtcttta
    25021 cttatttctt ctatatctaa atctggattg tctattgggt ctatgtctaa ttccttgata
    25081 gcttctggat aaacttctgg gaataatatt tctatagcat cattgtagaa tatacctttt
    25141 ccgtattgag tctctataac aattcttgga gctttacctt ttctaaatcc aggtatattg
    25201 tatttatttc tgcttttatt ataagcctta tttactgctg cttcaaattt attgttatct
    25261 actgttattt ttaaagtaac tttattaccc tcttttttaa ttagttctgc tttcatcctt
    25321 ctaatcctcc tagtgatatt tatgtaatac ccgataacgg tattataatt cattctattt
    25381 ataattcaac cacttaatta tatcacataa gtttttttat ttacaagtgt tccattaata
    25441 tcgttgtact tatttgataa aatttaattt tttgagcgtt ttttgccatt tttttagata
    25501 aatacacctt tatatgcgta tttcttcaat ttttatgtca tcttcttcta tatccataat
    25561 gacaaaactt ttatacgata ctcctcttgg aagtgaagtg cttccaggat ttatgtaaag
    25621 tacaccatct ttaatttctc taaatggggt atgggtatgg ccaaatataa ctatatcagc
    25681 atcaacttca gttgcctttt tttctaacat attagttcca tattttacac catacttatc
    25741 tccatggcat aagaatatgg ttttatttgc cacttcaaag acaacttctt cctcaacagc
    25801 atcaaagtca caattacctt taactgcaat aatacctaca ttagtcatgc tatgaatata
    25861 tcttgaatca gtaaagttat ctcctgcatg aattattagg tcacattctt tcaaatatgg
    25921 tattgttttt tccatatttt taatcatcat atgtgtgtcg cttactatgc ctattttcat
    25981 tacttcacta ccctttttat aaactcttgt ttcataagtt ttagtgcgtt tgctctatga
    26041 ctgattgaat tttttataac actaggtatt tcaccaaaag tcttatcata tccttttact
    26101 ataaataagc tatcatatcc aaaaccattt ttaccttttt cttcaaatcc tatcattcct
    26161 tcacaaattc ctcttactac aaattctttt ccatcaggaa aaactactgc tattgcagag
    26221 acgaatcttg catttctttt gctcattggt atattttgca tagcttttaa cagttttttt
    26281 ctattttctt catctgttgc atgttctcct gcatatctag ctgaataaac accaggtttt
    26341 ttgcctaaag catctacttc taagccagaa tcatctgata ttgctataag tttagtcttt
    26401 tttgctattg ttctagcttt tatcaacgca ttatgctcaa atgtttttcc atcttctact
    26461 atctctatac ctgctaaatc aacatctttt aaagagtaca ctttatattc aaaatctttt
    26521 aagatttcac ctatttcttc tagcttatga gcattattag tagcaatcac tacttcatta
    26581 ccataatcca tacccaatat ctcatctgat atttcaccta aagcttctct ttgaagcctt
    26641 attaattctt tattcccttt ttcacctaac tctaacaata aatttaaatc tgctctcgaa
    26701 aaaggtttct cttctcctgt cccctgtact tctacaaact cacacttatc agtcattatt
    26761 atattcatat ctacctgtgc tttagaatct tcttcataac ataaatctag catgtgtatt
    26821 ccatttacaa taccaacact aattgcagac acaaaatttg ttattggcat ctcttttatt
    26881 gtctttgctt tatataattt atatattgct tctgcaactg ctacaaatgc ccctgttata
    26941 gatgcagttc tagttccacc atctgcctga atcacatcac aatctaccca aatagttctt
    27001 tctcctaatt tattcaagtc tacaacagac cttattgctc ttcctattaa cctctgtatt
    27061 tcttgtgttc ttccatcaat ttttccccta gatgcatctc ttatctttct ttgttgtgtt
    27121 gctcttggta gcatagaata ttcagcattt atccatccag taccactatt tcttaaaaaa
    27181 ggaggaactt tttcttccac tgatgcagtg catataacct ttgtctctcc catttctata
    27241 agaacagaac cttctgcata ctttgtataa tctctagtta tctttacagg tcttatctgt
    27301 tcattacttc tatcataact tctggtcatt ttttatatcc tttctcatat tttttatttt
    27361 ttataaattt atttttataa tttttaattt tgtcaaatat taattattgt catttttcgt
    27421 aatcttatta gcttactgaa ctattctatc attaattata gtagttttct actaaattaa
    27481 gcgacttttt aactctctaa tacagctttt acttcatctt tcgatgataa ctttaataat
    27541 tctaaaaatc tctcttcatc tataacttta attcctaaat catttgcttt agtaagttta
    27601 gaaccagctt cttcacctgc caaaacaaat gttgtcgatt tactaacact agatgtagct
    27661 tttccacctc ttttttctat catatctttt gcatcatttc tttttaatgt aggaagtgta
    27721 ccagtcaata cgattttcat cccttcaaat attttttcta ctttttcacc tgtattatcc
    27781 aatgattttg tatttactcc tacatttttt aacttgttta taacgttcat atttttgtct
    27841 tccttaaaaa actcgacaac gctgtttgcc attatacttc caaattcctc taattcttct
    27901 agttgctcac tagttgcaga aattacttca tctaaatcct taaagttata tgcaagtatc
    27961 ttagctgctt taactcctat aaatttaata cctaatccat ttataagtct ccataaatca
    28021 ttttcttttg atttttcaat tgaatttatt aaattgtcag cagatttttc gcccattctc
    28081 tctaggtcga ctacatcttc cttttttata taatataaat cagatacatc ttgaataatt
    28141 ttttcattta atagcagtgt aattatagat tctcccaatc catctatatt cattgcatcc
    28201 cttgacacaa agtgtataat tccccttctt atttgggctg ggcaagacat attgatacat
    28261 tttacagcag cctctccttc taatcttatt gttggctctg aacaaactgg acacttttct
    28321 ggcattttaa aatctatttc atctccagta cgttcttctt ttataacttc taaaacttga
    28381 ggtattatgt cccctgcttt ttgaactaat actgtatcat ttatttttat atctttttct
    28441 cttatataat cttcattgtg aagtgtagct ctacttacag tagtacctgc aagtctgact
    28501 ggttcaagaa ttgctgaagg tgttattgta ccagttctcc caacttctac tattatatct
    28561 actattttag ttttcttctt ttctgctggg aatttatatg caattgccca tctaggactt
    28621 ttggctgtat atcccatttc gtctctttgt tttatattgt ttacttttat taccatacca
    28681 tctatttcgt agtctaaatt acccctgtta tctgtccagt attcaatatg ctcaataact
    28741 tcatctatac ttttacaaac tttgtaactc tgacttactg aaaatcctag tttttctaag
    28801 tactctagtg attcactgtg actttctaaa tcgtattctt ctatattttc catattaaat
    28861 acaaatatat ctaatggtct ctttgctgtt agttttgggt ctaattgtct caatgaacca
    28921 gctgcaagat tccttggatt agcaaataat ggctgttctt gttcttcttg ttgttcattt
    28981 acttttctaa aattatcttt tgatatatat acttctcctc taactattag ttctttttta
    29041 tcatttatct taagaggtat gctttttact gtcattaagt tttgagaaat atcttctcct
    29101 acaactccat ctcctctagt tgctcctttt tcaaactctc cattgttata agttagacct
    29161 acagaaagac catctatttt aaattcaaca acatattcaa cattttctcc cacatattct
    29221 tgaactctct tatcaaaatc tctcaaatct tgctctgaaa aagcatttga taaactcaac
    29281 ataggagttt tatgtacaat ttgattgaac ttatctaatg gcttacctcc taccctattt
    29341 gttggagaat caattctctt tagttctgga tgttcttctt ctaaagaaat taactccttc
    29401 attaacttat cgtattcata atctgatatt tctgggctat cttgattata atacctttca
    29461 ttatggtagt ttattgtctc tataagttta ttaatttcat cttttacgct cactttttgc
    29521 acctcttcat atttttaaaa ttaaattatt ttgaaatttc cctataatta attatctcct
    29581 atttatatat tttttagtat atcacttttt tggctttaaa tttattacaa aaaaaactct
    29641 tattagtatc tttaatacga ctaataagag tttttatttt tatcaaaatt ttttattttt
    29701 aatagcctct tgatatgtct acaacattat ctacaggttt attctccatt atatagtgtt
    29761 tcaaattatt ataaaccata ttaaatgttc tctctttgtt tttatctgac acccaagaat
    29821 tatgaggagt tactatgaca ttttcgcact cccacaactt attgtccttg tttaaaggtt
    29881 cactttcaaa tacgtctaat gctacccctc taaatttctc tacacattct tctaaatctt
    29941 tctgattaac tgtatttcct ctacctacat ttataaatac agaaccatct ttcataagtt
    30001 taaacatatc tttgtttact attccatctg tactttttgt agaaggcatt gctacaacta
    30061 ctatatcaca ttcttcaaat acaatattca tatcctcagt agcaaaacac ttatcaaagt
    30121 attttttact acttccatca gtattgacac cccatatttc tacaccaaaa gcttttaatc
    30181 tttttgctgc ttctgaagat atagtacctg ttcctaaaaa tccaactctt tgtccataca
    30241 attctgatac agaaaaatcc atcttccatt ctttattttg ttgttgttta aaaaattttg
    30301 cactattttt atatatttct aaaatataca atacaatact ttcaccaata ggtacactat
    30361 atccacctct attattagct atcttaatat ttctcttcaa tacctcttct tttggaagtt
    30421 ggtctatacc tacactagtt gtctgtatat attgtaaatt tttcatctta gaaatatcta
    30481 atctctcaaa tggattgtat gtaactagta catctgctgt atttacatcc tcattatttt
    30541 caatactatc ttcagagtaa tgtatgacat catagcctaa ttctcttatt ttatcaaatt
    30601 tttcttttcc ataatttatt gtaaataaaa ctttcatctc aaatctcctc catctaccca
    30661 catttaaaat tttatattct aaaatataat atgatactca atgtacatta gttaaaatta
    30721 ctataagata tcttaaattt acttatgttc aattgttttt cctaaagaca tagcattacg
    30781 ttcttgaact aaattttcta ttaaattatt caatgtccaa tcaatagatg tctctgttac
    30841 catagctgta aaaggtctat ttattctcac tttttttagc ccttctaaaa atgcatttac
    30901 ttgtgtgctt ggagtgttat taaatattac agacttactc ttaatcccat tttcacattc
    30961 atttgatata tttccatcta aaatgtctct tattatattc tctccatttt tatcacttaa
    31021 gatgatatgg tctcttattc cagcaaagtt acttacgttt ttaattaatg ataattcttt
    31081 tttattaaag tttacaagca taatacactt cctgttgtgt attttatcta ggttattatt
    31141 atttattttt tcaaatgaca ttttatccat cctttcattt atttatatac tttaatttac
    31201 cccatacatt taaaataatc aatttttata gttaattttt atattaatac ccaaattata
    31261 tttaaatagt taggctatcc aaaactaata tataaaatta gaataattag attaatatct
    31321 acaaatcata acctaaagga gagataccat gaatacatta ctaaacaata aatttagcat
    31381 taaaaacttt tcaaatgctt gggttatagt acttggttgt atgttgatac aagctgttcc
    31441 atttagtatt gtagcaagta tacagcctca atttataagt tatgttgtag aaggagaagg
    31501 ctttagttta gcttcttttt ctctaatatt cactattggt actattgcct cagcaattgc
    31561 atcacctttt ataggtgtat tattttctaa agtcaatatt aagatactat atttattagg
    31621 ttgtataatt tctagtattg cttttgctac tttttctata tgtactgaac tatggcaatt
    31681 ttacactgta tcatgtattg ttcaaattgg cgctacaatt atatctgcta taggaatacc
    31741 tgttttaata agtgcttggt ttgatgaaga aagcaaagga aaagctttgg gctttgcttt
    31801 tgctggtggt tctattggta gtatatttct acaaccactt gcagttcgct tattagcaac
    31861 tcaaggatac agtcgttctt atctaatatt tggaattata gcattaatag ttggtatacc
    31921 tgtaatatta tttatactca ggatgcctaa agatattaat gaaaaggtaa aatctaaagg
    31981 taaaaaagag aaagcatctg atacaatttc tccttcagta tggggttata cattaaaaga
    32041 agctaaaaaa attaaatatt tttggattat gactattgga tttatatttg ttggtatata
    32101 tgtttcatca ttatctgtac aatatccaac ttatcttaga aattatctaa atcctattct
    32161 aataggaaca gtaggctcca catttgcttt atttgctctc attggtaatt tatttggagg
    32221 attattgttt gataaattcg gtcaaacaaa gccacttatt atatcttttg tattggttct
    32281 tatagcaact ttatcattac tattggtaga taaatcttct acttttgcat ttgtatttgc
    32341 cattttgaaa ggtctttctg tatttgctta tatgattggt cctgcttatt taactggctc
    32401 tttctttggt caaaaggagt ttggtagcat atatggaatc gtacaattaa tttttgcagt
    32461 gggatttgca ttaggttcaa cattatttgg attgttagtt gataattttg gatacagatt
    32521 ttcttggtct attataattt tatcagttat aattgcctat actttactta ttataacttc
    32581 tataggaatg aaaaatttga ataaagaaag attagataaa ctaatgcaat aattgatttt
    32641 tagatatata aatattataa taaaaaagat ggagctttta atcataaata aaactccatc
    32701 ttttttatat tacaatatag ctaattttct cttattttta actttactat ctatatcctc
    32761 atccttaact atagtaaatg ccttagttgg acaaacattt acacatgcag gcccttctgg
    32821 cgattctata caaaaatcac acttatttgc tgtcattctt tctctaaagc aaagctttcc
    32881 ttcatctaca tcttttaatg taactatgtc tattgcacct ataggacatg ctaacataca
    32941 agtcttacat cctatacaat tttcttcatt gatttttatt gtgttaccaa ccctaactat
    33001 accaccattt ggacatgcct ttgcacaagg agcatcttca caatgtctac actgtattgg
    33061 agcacttact tcttttgtct ttatgacaga aagttttgga ttaaaattta tttcatctgg
    33121 attttggtaa aaaatatctt catctgaatg tgcaactaca catcctatca tacaagttct
    33181 acatcctatg catttatcag ggtctgctat aacaaaatag ttcatcactt agccacttcc
    33241 tttcctatac aatatgtagt gtgtaataga tgatgagatt tttctcctaa tggttctacc
    33301 agatattcat catacagttt tttaatatca ggattctcat gagattttct aattgctaaa
    33361 tgttcatcat gcacgtatgt tgcttttgtt ctattttcat aagccaattc cttatattct
    33421 tctagtaaaa tttttggttg acctccacca cttacacacc caacaggaca agtcataact
    33481 tcaataaaat ctacatctaa ttttcctttt tccaagtctt caagcactgg tattacattt
    33541 tttaatccac ttactactcc aactcttaag tctaagtctc ctattttaat agttgacttt
    33601 ctaaaaccat tttctcctct tacttgtttt acttctacat caggaatact ttctccagtt
    33661 ataagctcat atcctgttct tatagcagct tccataaccc caccagtaac accaaagata
    33721 gttccagctc cactataact acctaaagga ctatcaaatt tttcttctct taaattttta
    33781 aaatcaattc ccatgtcttt tattaaataa gctagttctc tagtagttaa tactacatct
    33841 acatctctat atccactaga atccatttct tctctatcac attcatattt tttacatgta
    33901 catggcatta tagaaacact aaatatcttt gatgcatcta cattatttat ctctgcacca
    33961 taagttttaa atattgcacc acccatctgc tgaggtgatt tacaagaaga taaatgatta
    34021 gttaatttag gataattttt ttccatgaat tttacccaag ctggacaaca agatgtaaac
    34081 attggaagag ttccaccttc tgtcactctt ttaattaatt cactaccttc ttccattata
    34141 gttaaatctg ctgcaaaatt agtatcgtag actctatcaa aatttaaagc tctaagtgct
    34201 gctgccattt tcccagcacc taagtatcct aaataatatc caaaatcttc tcctaaagca
    34261 actctaactg ctggtgcaca ttggaccata gtgaatacat ttgggtcact taaagctttc
    34321 ttcaccttat ctatatcaca tacattgtat gctgcaaata taggttcatt tatagactct
    34381 ggtatctctc tttcttgttt tttctcttgt aaaaactcaa atccttcatc tataactgag
    34441 gcataagatt tacaagtttg aacacattga ccgcacataa cgcatctatc taaatttatc
    34501 tcttgtggct ttccctcttc accttcaata gcatttactg gacagacctt tgaacattct
    34561 ctacatccag tacataaatc cttatctata tttattatca taaacgtcac ctacccctgt
    34621 atcctttatt tatttgttaa caataaacta agtgcagctt gtctattctt agcttttttg
    34681 tcatctattg gagtaacaag ttttaatgct tcctgaggac atgcacttat acaagctatt
    34741 ttttcattgt ctttacataa gtcacattta taagctatct tcttattttc atctaaaatt
    34801 acttgttcta cttctttacc atcttcatat tgtggaagta agtctatagc tccaaaagga
    34861 catgctagca gacaagtttt acatcctata cacttttctt catttacaga cataatattg
    34921 ttttctttaa ctatagcttt ttgtggacat gagtttaaac aaggagcatc ttcacaatgt
    34981 ctacactgta ttggcataca gaaattgtca ccttttacta agtaaagtct aggtataaca
    35041 ggtatatcaa ctgttccaac tgtataaccc acattattat gctgattatg cattgtaaaa
    35101 caagctactt cacaagctct acaacctgta catttgtttg ggtctgctat tacaaaagag
    35161 cctattttat ttttcatatt atcccacctt tcaatttgta tatttccaac catctagtta
    35221 ttttcatcat atgtctactt actttcatca tatatattta tatatttcac tattttctca
    35281 gtacttatat ttcgtttaca ttttttgcac aaattgtatg tgttattata caccttatca
    35341 gtatcatcaa ttaatactcc acagatttca cactttgaat atctttgctt ttctttttta
    35401 gtacacatat attcattctc actttttgat aactctctgt ggatttgcat aaatattcat
    35461 ccgtcttcct cttacaaatc caataagcgt tatatttaat tttttagaaa gctctattga
    35521 taaattagtc ggtgctgatt ttgatactac aataggaatt tgagtcatag ctgcttttaa
    35581 tatcatttcc aatgatattc ttccacttac agccacaatt ttatctttta atgttatgtc
    35641 atttaaaaca caaaatccaa tagccttatc cattgcatta tgccttgcta catcttcaca
    35701 agtgactatt tttttatcaa aattaaatac agatacgcta tgtaccccac cagtattttt
    35761 aaataattct gatgaattta aatttttatc cattatactg taaatcgtat cataatttat
    35821 ttttatattg ctctttacag gagcacaggt tatatagtct agtgaattta aaaatataat
    35881 ttgctcatct tgattttttt gtttctcttg aatagttact tttgcaaaac gttcactctc
    35941 atttatctca aattttaata agcttttttt gttttctatg tatccttttg ttttcaagaa
    36001 tcctactata agttcctcta aattatatgg ggtacataaa aatgtattta catatttatc
    36061 atttaaaata aaactaagtg gatattctgc aattatttct tcattatcta ttgatacttc
    36121 atgttcattt attttgctta cttctacatt aaaagaattt aaatatttgt agtccactag
    36181 actataacta ttttcaaaaa ctttatcctt actattttct tgtaatttag tttttgagta
    36241 tatattgttc ataaaatatt agcctttctg ccttttataa atcttaaatc aaataaatca
    36301 ttagatattt gtagctgtca ttttgtcttt caaactttga tactcttctc ttacacattt
    36361 ttctgctaat tcttggtctt caagtttttc aagtttaaca gcacaatatt tatactctgg
    36421 tgttttagat atagggtcta aatttgctat tgtaagttca ttgcaagctc caacccacca
    36481 ctgataagtc atatatgttg caccttcctt aactctatca gtaactgttg ctcttgttat
    36541 tacacttcct cttcttgaac taattctaac taattcatca tcttcaattc ctaatttttc
    36601 agcatcatta gaatttattt gaacacgtcc tggttcatct tctaatgaac taagtgttct
    36661 acaattacca gtcattgttc ttactgaata gtgtccaact tctcttacag tacataaact
    36721 aaatgggtat tcatcatctt caacttccat agggggtctc cattcagcag cgaacaaatt
    36781 acctttacca ttaggagtag aaaacttttg accttcatac agatacatag ttcctttatc
    36841 ttccatactt tcactcttac aaggccattg aacgcatcct tgagtttcta tcttttcata
    36901 agtagcacct aagaaacttg gacataattg tctaagttcg tcccatattt ccttagtatt
    36961 tttataattc ataggatatc ccattgctgt agaaatttcg cttataattt gccagtctgg
    37021 ttttacatct ccttgtggct ctatagcttt tctcatcaat tggaatcctc tatctgcaca
    37081 tgtatatact ccctcatgtt ctccccaaga agtagctgga agtataacat cagcatgaag
    37141 tgctgtctta ttcataaata tatcttgaac aatgacaaat tccaattcat ctaatgcttc
    37201 tctaacttct gacgcatctg ggtcactttg cactgggtct tctccaaata tataataagc
    37261 tttaagcttt ttctctttta gtactaagtc tggaacttga gttaaactat aaccattatt
    37321 aggagataat tttacccccc aagctttttc aaacttttct cttatcttat catcagttac
    37381 attttgatag ccaggatata cattaggaag agctcccata tcacaagctc cttgaacatt
    37441 attttgtcca cgtacaggtc ctattccaac gctttctcta ccaaaattac ctgtaagtag
    37501 agcaattgat gcaagtccct taactacatc aacagcttga ccaaattgac agacacccat
    37561 tccataaagt atcatagctt ttttaccttt tgcatattct ctcatagctt ttcttataag
    37621 ctcttctggg attcctgtaa tcttttcagc atatttagct gtatatggtt taacaatttc
    37681 tttatactca tcaaatcctt gtgtatgatt ttgaacaaat tctttattgt aaagaccttc
    37741 ttctattaat acatttccaa aagcatttac taaaaccatg tttgttccac cttttatagg
    37801 tagatgtata tcagcaattc ttgcagattc agttactcta gggtcagtaa caattaattt
    37861 agcaccattt tttttagctt ttactattct atttgccact attggatgtg aatctgctcc
    37921 attatatcca aatataaata aaacatctgc attttctatc tctggtatag aattagacat
    37981 tgcaccacta cctaatgagt aagccagacc ggctacagat ggtgcatgtc agacacgagc
    38041 acaatggtca acattattag ttcctattgt agctctcata aatttttgca ttatatagtt
    38101 tgcttcatta ccaggtcctc ttgcagaacc tgttcccata atagaatcag gtccatattt
    38161 ttctttaatt tcatttagtc ttgaagctgt atagtttata gcctcatccc attcaacctc
    38221 ttctagtaca ccttgttttc ttatcattgg cttttttagc ctaggtgtta gaattttagg
    38281 gtcatttaga aaatcccatc cataacgacc ttttaaacac aaactttctt gatttgttct
    38341 accattagcc ggttcagctc ttaatatctt attatctttt actactagat ataattggca
    38401 tccagctcca cagtatggac aaactgttaa aatttttttc tccatacaat tcccccctta
    38461 gatttatccc ctgataagta aaatttatct taaagataat gagtgttttt ataatatgca
    38521 aaatcataaa tattttgcaa tactatctat taaattcaac aattttctca caattcctct
    38581 taaatttcaa aaaaaatatg tcataataat ctttatattt caaccattta attaaaatat
    38641 tctagttctt atgacatatt ttttaatata ctcaatatat attctttaaa cttatttagt
    38701 tttcacttaa aacaatattt ctgccaattc tatttttcat tctatagtga gtaattacag
    38761 taaatattcc acttccaatc agaatcaaat agtacataaa tccaccatat aaaaatactg
    38821 catatcccat caaaggttga gggaatactg atttgaatat agtgaaaaag gctaattcat
    38881 tagctcctac attcccaggt gttggtattg gagatattgc catatataaa aatgcttgta
    38941 atgtcagtat ataaatatag ctataacctt gtaaattaaa tgctttatat atccaaaatg
    39001 aaacactaaa gtaagcactt aattgaataa aagttactat tatagttgaa attaatacct
    39061 ttttattctt tgcaaaaaaa tttattgctt tactataatc atctataaaa ctttctatgg
    39121 attcaatctt attatctaaa aattttaaaa acttaatttt tgataaatgc tttatagtaa
    39181 ttctcataaa atattttatt tttttaggat ttaaaataac taatattatc ataattaaga
    39241 caaatgaatt aatggctatc cctagaaaca ctagaggcat aatcattttc atttgttttt
    39301 ctaacatagc aaaattcatt aaaacaagta ttgtacaata aaaagtaact actatttgga
    39361 agataataga cttattggta acaactgcac ttgccttact aagtggcatt ttacattttt
    39421 taagtacata tatctgtact ggttggcttc ctgaagcaaa aggagttatt aaattataat
    39481 aaaatcccat aatggctagc ttaaaaccaa taaatctaat attaactttg tgagtgcttt
    39541 ctataattat cttcattact actccttcaa gcattatgtg acacattatt gccaaagcac
    39601 ctatgaataa aaacttctta tctaccataa ccataacatt tgatagcatt ttaatatcca
    39661 atgttttaaa cactaggtaa attgttatac ctattaacaa aaataaaaat gtatactgta
    39721 gtaaactctt tctaatattc tttagtctat ccattagaaa taaccatcct ttgctcaaga
    39781 tttatactaa atactatatt attagtatac actatgaatc ttaatatttt ataacaaaat
    39841 accttacaat tttgtcattt acaaaaaata ttaatctata aattaaattt taatatatag
    39901 attaatattt tacaaacatt ttgtagatat atataatatt ttcactaaac aacacttata
    39961 cttattacac ccatttatac cctatccccc atacagtttc tattgtataa atatcatatt
    40021 gttttaattt gcttcgtata ttttttatat gctctgtgat agtacttata tcactttctc
    40081 catcaaaacc atataccgac tcatatattc tttcttttga aaatacttgt cccttatttt
    40141 ttgctagaaa ttcacatatt agatattcac ttttagtaaa attaattttt ttaccatcaa
    40201 ttgaaacttc tttgcctaaa aagttaaatt gaacatttga gatagttaat aaattctttt
    40261 tttctctact ttctcgcctt aaatgagcag ttatcctagc ccttaattct cctacaccaa
    40321 aaggtttggt tatatagtca tctgcaccta taccaagacc gtacataata tcactttcca
    40381 tattttttgc tgtcaaaaac agtattggac aatcaacctt atttcttata gttttacata
    40441 cttcaaaacc atccatctta ggcatcataa catctaatat tattagatta aaataattaa
    40501 aatccatgtt catagccttt tctacatcac taattacctt tacttcatgt ccatctcttt
    40561 tcaacacatt ttcaatcaac tttaacatat ctaactcatc atctactact aatatcttag
    40621 acataataac tcctccattt atccatctaa tagcattcta atttatatat ttaataatat
    40681 ctttaaaatt cacattaacc ataatactct catattatag cttacaataa ttaattacta
    40741 ttttacaaat aaaatatttt agatacaaaa actttatatt tcaaaaactt tatattcatt
    40801 ttacacgtat ttacttaaat ataaaaattt atttaacaat ttattattgt aatattttga
    40861 atatataata aaattaataa taagaaaact ttttataaat atacttttaa ttgtttaaat
    40921 tggaggaaaa aattatggat gaaaagataa caaaaaataa ttataatgtt ccatttgact
    40981 atgttcgaaa aaaactcaaa gaattagacc ctcatacaat tagtaattta agtaatatac
    41041 ctttcaataa tgatttaaat agattcacac tcaatttttt tgatagacaa tatattatag
    41101 actatccaag tggagaagtt tggaatagta atggtagcct ttgcaataac tttgagctta
    41161 aaatcttgat agttagatat ttaatcaatg ctaaaggtat ccctagaact aataaatatg
    41221 taacttttaa agaaatacca ggaggcaatg tttattatcc aaatttttta aacaggactc
    41281 tatataggct ttcagaagtt tttacatctc aaatagacaa atataagtta gttatggaga
    41341 aaattggagc tgaaaaagta aacatgggag atttagctta taggtttaca tatatgggta
    41401 atacatctat ggtatttata ctttggtttg gagatgatga atttcctcca aattcaaata
    41461 tattatttga ttctaatata gtttattact tcaatgcaga agatttagca gttgttcctg
    41521 atacagctat aaatgcaatt ttaaataaaa taaatcaatt ataaatataa ataatattat
    41581 aataaagttt ttgatagatt taatagaata taatatgaaa tggagtaaaa aatgaatgta
    41641 gaaaatcaat ctttatcaga tattgaaata atattatcac acaggtatga taatggtgca
    41701 gactattgga ctacacctga taagcgttta ataaaaggtt ctcctttctc tactcttgat
    41761 agtgtacttt atctattaga attaggtgtg aaccctgatg atactttact taaagaatgt
    41821 gctgacctga tatttagcac atggcgagaa gatggacgtt tcaaactata tccaaatgga
    41881 ggtatttacc cttgtcatac tgcaaatgct gctaacgtac tctgtcatat gggatatgca
    41941 tctgacatta aaatgcaaaa aacgtttcaa cattttttag atacacagta tactgatggt
    42001 gggtggcgtt gcaataaatt tagttttggt cgaggtccag aaactgaata ctcaaatcca
    42061 ctaccaactc ttaatatatt aaatgcattc cgttttagta attatctaaa taaagaatca
    42121 aaacttgaca aagctgtaga ttttctactt gaccattgga ctattaaaaa accaatcggc
    42181 ccttgtcact atggaattgg cacattattt atgcaagttg aatatccttt ccgtaattat
    42241 aacctattcc tttatgtcta cgttttatca ttttataatc gtgcaaaaaa ggataataga
    42301 tttttagaag cattgaagat acttgaatct aaaatgatag gtaataaaat tgtcgttgaa
    42361 cgtgtagttc caaaactatc taaattatct ttttgtaaaa aaggcgagtc aagtgaaata
    42421 gccacaacac actattacga aatattaaaa aacctagaaa aataatagtt atatagataa
    42481 aacatattaa aaaatagtgg ctttaaattt tttaaagtca ctattctata taaatataac
    42541 aatataaaaa atatattaaa ctatttactc ttttttaaaa ccgttgattt tcttgctata
    42601 taaaaaacta ttattataga aataactact agagaacctc tatttataaa gaaataattc
    42661 tttaattcat taaatctaac atctatattg ttaggcatat aaaacatctt ttgaatataa
    42721 aatccattta cattaatcat actaacaaat gggtacatat gtaaaataaa aaatatatca
    42781 gcaaatgtat atgtaattaa tattgctatt gttgtaaatc tattttttgt taatgttaat
    42841 atcattagtg gaaatgttgt ataccataat aatgtaggaa acgtctttaa aaacacatct
    42901 attggcttta cactataaac aaaatctatt ttgtctatgt taaaaccttt cactgacgta
    42961 aatgtatata ctattgtaat tgaaattaat aataatacag tatatatagc taatataaca
    43021 caccatctaa atactataaa ttgattatat ttttttttat tatataaagt aagtatctca
    43081 tttatattac ccgaataatc ttttgaaaac acataaatta ttgtgattgc tgacattatt
    43141 ggtataaaaa catctgatat ctttataatt cctaaccatc ctgctataga atatgtatcc
    43201 attataggta catcattata aaatattaac tcattataat ctaatatgcc tgtaataaat
    43261 atgcataata tagaaataat tacaaatatt aacacatgtt taagctctat ttttttaagc
    43321 tcaaatttta ttaactccaa tatacacatt tattttaact ccttatgtaa aaagtttata
    43381 taagcatctt gtaaagttgt atctatcctt aagctatctt taagtttctc tgtattttta
    43441 cctatatact ttacttgcac accatcttta actctcctat aatcaataat atcaatatta
    43501 cgttctaaat attcaaattc atcattagaa actactaccg aatacacctc aaccatatca
    43561 ataaacttat taattgtacc atcatataat attttgcctt gatttaatat aattaatttg
    43621 tcacagttaa attgtatgtc ttctactatg tgagttgaaa ttaatactat agaattttta
    43681 cttatttctg gtaacaatct tctaaattca ttcctttgct ctggatcaag accaactgta
    43741 ggttcgtcca taactattaa cttagaatca cctattaaag cctgtgctat acctagtcgt
    43801 ctctttacac cacctgagta tgtacctatt tttttattta taaacttgtc cagattaact
    43861 tttgatacta ctttttgtat atgtttcttt aaatcattct tagatacacc tctcatttta
    43921 gctacaaatt ctaagtattc ttgcccattt atattattat acatatcaaa atcttgaggt
    43981 acatatccta catttgcctt gattttctca ttgtttttgc tatactttat attatttaat
    44041 tctatctctc caattgaagt ttcataaaga gtcactaata acctcattaa tgttgatttt
    44101 ccagcaccat taggacctaa taatgcaact actccatctg ttagggttaa atttatatta
    44161 tccagagctt ttttattttt gtaattaaaa tttagatttc ttatttctaa cttgtttatc
    44221 atattaacct cctttattat ttatctatta taaggatatt tcctgaaagc caatgataaa
    44281 tagttatgct aattttctct ccctttgagt cttcatataa aaattcattg ctaggtaagt
    44341 cagcaactaa tatcatatta attttttttc tttttattga ttccataaca ttatctactt
    44401 catctacata ttttttagca tctacagatg ctttgctatc acctaatatt tcatttcttg
    44461 tttcaattaa aaatttaatt ttttcctcta tatccatatt tacattacta tctgatggat
    44521 agattatttt tatatcatct tttacctctt ctttaaactc acctgcatat attgcaatat
    44581 catttgactt tccttcaaat atataatctt tttttaaaaa attactagtc ttattcagta
    44641 aaggtaaatt tgaatagaca ttatttttag aacttaaatt tattttataa gccatacaac
    44701 ttgattgatt tacttttggg taccacgcta aagaacctgg tggaagcata atatcatctt
    44761 tagtagctat atatttattt tgattccaag atgtcaacac attaatatag ccttcatact
    44821 ctatatctaa tgtcacctcg tcattaggct ctaaactttc ctttaaatta acttcaatta
    44881 aatccttttt tttgttaaat tttatatttt ccgaatttat ttttatatat tttatatcaa
    44941 atatttcatc taaaatcata ttaatatttg ttaactcttc atttgatgtg tttaataaaa
    45001 caattctatc ttttatattt gacttgcttt taaagtcaat cttcatatca tgcgatttta
    45061 ttttaatatc actaatatta gatttcttta aatactctcc ataactacgc tcctcatctc
    45121 tatatgttga catatctatt gatatataat ttaatccaat aaataaaata ctgtacacta
    45181 ctataactat taatgattta atctgtttct ttctaatatc atttaatatc agatatgcta
    45241 ctattattaa agtaattgca aatagtgtag gtataatctt atctataaca tatgctgaat
    45301 tattaacttt ccctacaaaa tcagaatagt aagcatatga ttgatcttca aatatgttaa
    45361 gtgatttaaa taatgcttta aaaaatggtt ctttaatatc aataactcta tccaacatat
    45421 tagttgatgt taaatataaa aatactgatg ataaggtaat ctttagtatt aaattattta
    45481 taataactga aataaatgat atcactatag ataaaatagt aagtggtaaa aaccattcaa
    45541 atatcaatat aaatatagtt gatttaatcg ttacaattga caatgttctt attaaacttg
    45601 agtatgctat agcatatata attggtatgc aacaaaatat aaagttgttt ctagttacag
    45661 caacagaaat acctaaaaaa taatcaaaat tatttctaca taatattttt acagtatcat
    45721 aactttttct catataaaaa attacattta acatggttaa aatactaatt gtcatacaag
    45781 tatatacact caaggataag taatcattaa atgaaattcc tctattggat atatgtgtcc
    45841 atcgttgtat gagatggtaa tttataataa taattgttat tgcaaataaa atattttttc
    45901 taattatttt ggttataaag tctgatataa ccttaatact actcatattt atgcccctcc
    45961 tagccagtct tttgattata acaattacaa aaacatccta taaaaataat tataggatgc
    46021 ttttaatact aatttaaagt tgcatatgtt ttagcattat tcgttgaacc ttcatacctt
    46081 atatagtatg ttcctcctga taaactaact tttgaagaag catttgcttc atgtcttttt
    46141 acaattctat ctgggctaga tcctgagaat ctttctgtta gcctacaaga aaatccccct
    46201 tgagaatctg tcgttttaaa ggttctactt ccagaagtgt atactgaact agatataata
    46261 ttgtttttac ctgaaaaagc tttagatatt aaagcatatg tgctaacctc atctgcaaat
    46321 acagatgtcc ctaaacttga tacaattata gttcctattg caaatgtaac tcctaacttt
    46381 ttaatttttt tcttcaaatt cattgtatgt atccctcccc ttagttaata taatttttat
    46441 aaaaatgtaa tttcaaatta cattttcata ctatcgtatt aacttttaca attcaatact
    46501 ctgttacaaa ctggttatta agtgaatcta tttgtccttt gatacaaccc acaatagatt
    46561 caactatatt taataagttc aaatacttac cttgacatta tttttttaaa gttaatatta
    46621 attagtgaag ttaattaatt tagaaaatgt tttataatct tactgatcac tattaacctt
    46681 cattccaata tatattaata tagcaatcca atatatagaa attattgcat aaatcacata
    46741 ttgctgaaaa atattaagta ttttacataa aataattaaa catattatta cgaatagtat
    46801 tttttgcaca gtctttctat aatgcttttt ctcactttca ctaagaggtt tgtttctatg
    46861 ttctaaagga gctaacttgt aaattgttag tatactaata atcattaata atactaataa
    46921 atacttatat ttatttatat ctatattatt agctgaaaaa atagttatca aataaataac
    46981 tacaaatgtt aatgtacact ctttataatt cctagcatga taacctcctg tgaactgtct
    47041 taaagtgcaa taacaactta aaaatataac tgtatgtata aatctatcaa aaataattcc
    47101 tataaataat gctaccaaaa tattaactat gaaataaatc aaagtttcaa atccatatct
    47161 atatatttca aaatcttcac tttctacaat ctcattatta actaatatat tggcaaattt
    47221 atatgataat cttttaaaca tatttcctcc tcaacatgta aaacctctcc tttaataaga
    47281 agaggtcctt ttattaatgt tattttttta gtttttgtaa agcttgtggc tcttttgcct
    47341 gatgtgctac ccaagaactt gcactgtttg ctgataatac agctatccca aaacttaatg
    47401 ctgagatgtt tttaagtaag tttaacgcta tttttttcat tttgtactct cctaactttt
    47461 tattggtatc attattttta atataaactc attatctgag taattaacta ttgtttcacc
    47521 accatattta tttactatat atttaatact agcaagtcct attccatgta tattatcatc
    47581 atccttacta gtttgaatac gtttatcaat aagtttaata tcatttacct tagtatttat
    47641 aaattttatt attgcaaatt tatttatata tgtagcttta acttctattc ttttttctat
    47701 ctcattattt atatccatac atgcttcaat tgcattatct agtgaatttg caaatattga
    47761 acatatatca ttatttttaa taaagtttaa tttagatata tttatgttat cttcaatttg
    47821 aatatcatac tttttacaaa tacttatttt ttctgctaaa attaaatcta atgttttatt
    47881 tccagtattt ttaaaatgtt caaattcact tatctgaaac tctaagttat ttatatatga
    47941 tataatttct tctttagtgt cataattttt tatacaaatc atatggtttt tcaagtcatg
    48001 ataaacatat tttaatctat catgaacttc gtttatattt tcataattcc tgtagtttgt
    48061 ttttattctt tcatttataa gttcatactc tagatttaat ttatcgtctt gtacaatttt
    48121 ccctattact attaaaagta ttatacttga tgataaaatc aataaaattg caaatataaa
    48181 tataaataag ttttctgtag taattgtatt gactcttaaa ttatattcaa atataagtaa
    48241 taagctaact atattagata atataggtat tcctattagt atcatatctt taggtttaaa
    48301 atctaaagat aatttaaaat acttaaacaa tataaaacct ataaataaaa atacctttga
    48361 cataataata gcttgtattc taaataagtt ttcatgttgt gttatgttaa tattatttaa
    48421 tttatttata aatactacta gacctactgc agaaccttca gcaaccatta atcctagcca
    48481 aaacaataaa ctaactatta tacttttata gattttatct tcatatgatg ttatataaaa
    48541 tgatattcct attaccatac atagaagaat cttaatattt ggaaacactt taactacatt
    48601 tatgtatgcc ataaatataa ttataattat tgttgtaaat atatatctta tattagatat
    48661 tttcctcttt ccaactaagt ggattactaa aaaaaatata atccaatcta tagtacctga
    48721 aactaaatta ataatattcc aaaatcctac acttaaattt gttagcatac tatgtcccct
    48781 aatatattag ttatcgcaag cttcaagcct ttaaccctat atttacttat tggaatactt
    48841 tttccatcta ctataacagt acttccactc attgattcta ctaattttaa gttaactata
    48901 tagctattat gacatctaaa aaatccatat tcatttaata tcttttctat tttagatata
    48961 ctcattttag taatatacat atcatcatgt gtataaatca atatattcgg tctatctgtt
    49021 tctatataag taatagaatc tattttaatt cggtctacat aattttttac atttatagtt
    49081 aagtaattat ttctcttttt catcatctca tttatacaag gtaatacact tttagaaatt
    49141 ttttctttat ttattggctt tagtatatat ctgtatgctt ttacctcata accttcttgc
    49201 ataaactcta caaatgaagt aacaaatatt atttctaact tatgatcaaa ctctcttatc
    49261 ttcctagcag tatccatacc atttattgtt ttcatttgta tgtccataat taatatgtct
    49321 aaatctttag gatagttatt tagtaactct tctcctgctg aaaattcata tatgttataa
    49381 tttataggat atgaacttaa tatttcactt aatatatctt ttatttttat tcgataatgt
    49441 agttcatcat cacatattcc tatattaatc acaattctta aacatccttt cttatatatt
    49501 tttaataaaa atatataaat ttctattcat tttacatatt ttaacatact tctgtagtaa
    49561 atagctattt agattttaat tttagctttt tggacattaa gtattacttt ttggatttgc
    49621 aatctatttt gattttcatt ataatacaat tttttaatat atattaaata tatttaggga
    49681 ttttaataaa atattcctcg aaaagttttt aatatctagt ttttgttaaa taaaaagtat
    49741 gcaccttcct ttttatagta atgttttaat tatcgctata aatttgaaga atacacactt
    49801 tattttaaat actcatataa aacatattaa aaaatagtgg ctttaaattt tttaaagtca
    49861 ctattttttt aaatgatgtt cctgaaaata tattaagtta gttattctaa tcagtttgaa
    49921 gacttttgct tctgcttgcc tacctctaac acaatttcat aatttaattt acttctcctt
    49981 aaatcaactc cagatatact tttaatagtc ccacaatcta acatttcatc aaatgctttc
    50041 ctagataaac ctagtttttc acgtaataat gctgacacct ttaattggga tggatactta
    50101 cttacaatac gaacttgtgt aaggtcatta atatcaattt cttgtcctac tattttatat
    50161 tctggaatac caacctctgc tccatttcta tgtaaaagtt ctacattcat agcatattga
    50221 ttagcaagat tatcatcatt tgtatggaat tgttctagtg tttctgtact taatctattt
    50281 ggattaacac gagaatatat agttgagttc catgttgaat cacaatttga acacttgtat
    50341 attaaccata tatccaaata tttatgttga gcattaaccc taaataaacc tgaacaaata
    50401 tattcagtct tttttccaca ttttttacaa tacctaatta caggtaactg ggagatatat
    50461 tccacctccc aagtaatttt tttcataaat gcaatttcct ttctataaga ttactaaatt
    50521 aatagaaagt tatgaaaagg tggaatataa tcaagtattt ttttcaaaac aagacctcct
    50581 aattttaata aattttaatt tcaaacatat aaaaagctac tacttcttat tagatacttt
    50641 acaaccagct ttgttagcta ctgtataagt tattgaaatt acttaaatta tatcatccac
    50701 ttaaaagaaa ctatacctca aacactttta tcaaaagaaa atgagccagt ataattataa
    50761 aactatactg gctcatcctt agatatcttt tcttttttct tgtaatacaa ttctttggat
    50821 acttttcaaa gataaataat acttttccga taaatattgc aaatcatatc caacttgata
    50881 gtcttcgtaa atctgcatat ttctaattga caactcctca cgagtaggtg tattacttcc
    50941 ccattctttt ttattattag attttctagg aatatagata cattcaccat ctacatattc
    51001 ctgtattaat tcaagtaatt cttctggtaa tatatgtatt gcttttttat agctcatttt
    51061 gctctcctat taaatagtaa tttttcatta ggaatagcaa agggctattt atatattaaa
    51121 tttcatagtt gcaatagccc ttgctatgca aaaataaaga ttaaatcaaa cataaaatct
    51181 caaccctcct tatatatcac agcgatacat ataagtctat caacagtata actggttgtc
    51241 aatcaacaca aattatttat ccatttttta aacacattta tttagttttt atattatatt
    51301 tattttgata actaaaattt tttcattata aactatcttt aaaattatta gtcaacttaa
    51361 atccattatc ttgatgggtt tattactgaa caaggaactc caactataca ctttccacaa
    51421 atatcacatc cacctatata agtgtatttt ttttcattta tcatacacat ttcataacac
    51481 ttattcctat taaatccatc ttcttttaaa gcttctttca cgcatttgtt gacacatttt
    51541 ttgcaactat tattatgttt atacaagcag tattcatttt ctggtctttt agttggctct
    51601 aattctaaac ttgtgattat gcttcctatt cttccacaac accctttttc tgtaataagc
    51661 atattattta aaccaaaagt tccaagacct gctatgaatg ctacatgtct ttgtgaccag
    51721 tcacttacca atttttcact gtcaaaatta tacgacccag gaatagcata tgaattagcc
    51781 cccatcttct ctagttcttc acataagaaa tcatttaaat ttgaaatcaa catattagtt
    51841 tctatgtacg ctcttgccca tatttcagaa cattcaaacc ctccaatatt actattattt
    51901 acactttcat caaaaggtat aaaatatgta attatagttt ttccattttc cagaaaatct
    51961 tttggcatag catgagatgt tcctacaaca ctttttagct tctgaaacat atcatcttca
    52021 gcagatgcat aagcaaacaa aagttcttgc cactttgtag ttatattatt tgatttatga
    52081 taatttttta caaagttgtt cattgatatt tcaatcttat ttttcatagt atcaccccta
    52141 gataattcta tatttccaat ttaatgttat tattttatat tatataatag tattttataa
    52201 tatgcgcact aattaatatt aaaactatgt tcatcaatca ttcttaaaaa agctcctaat
    52261 atcaatacga tattagaagc cttttcttat ctaatctaat ttattgcaat tcctgcactt
    52321 gcatatcctg ctacagtatt aactaatgaa agacctgaag ctgttgcagt aaatactagt
    52381 aagaatcgag tttctgctgt tgctgctata tttaatcctg ttacaattcc actagaaatt
    52441 gaaccaactg ataatattcc tgtaagtggt ggagctagtg taactgtcgc tcctggtaca
    52501 gctgtaaatg agttatttgg tgcagtagat tggtaaagtg ttgctgtaat tgtaactgtt
    52561 gagccaacaa gtgaaagtgc tgctgttgta ctgaagtatg ctgaaataga tgttattgtt
    52621 ccagctcttg gcattgaaaa tgcaaagtta gtcaatgttc ctgctgcgtt tgtaaggtct
    52681 attactccac caactatact taatcctgga gctgaactac caaagccaac aaaacctggt
    52741 gtacctacta atcctccagc tatagttgta agtgatagtg gtatacctga tgcaaaaggt
    52801 attattgcac tagcacctgt tggacctgtt gctcctgttg ctcctgttgc tcctgttgga
    52861 cctgttgctc cggtcgctcc ggttgctccg gttgctcctg ttggacctac taatccatct
    52921 gcccctgttg gacctgttgg acctgttgct cctgttgccc ctgttgctcc atctgctcct
    52981 gttggacctg ttgctcctat tgggcctgtt gctcctgttg ctcctgctaa tcctgttgct
    53041 cctgttgctc ctgttggacc tactaatccg tctgctcctg ttggacctgt tgcccctgtt
    53101 ggacctgttg ctccatctgc tcctgtattt cctgttgctc ctgttgctcc tgttggacct
    53161 gctactccat ctgctcctgt tgctcccgtc gctcctgttg gacctactaa tccatctgcc
    53221 cctgttggac ctgtcgctcc tgttgctcct gttgctcctg ttattcctac tcctgttgcc
    53281 cctgttggac ctgttgggcc tactaatcca tctgctcctg ttgctcctgt tgctcctgtt
    53341 ggacctacta atccatctgc tcctgttgga cctgttgctc ctgttgcccc tgtcgctccg
    53401 gttgctccat ctgctccggt tgctcctgtt gccccggttg gtcctattag tcctgctgct
    53461 cctgttgccc ctgttactcc tgttgggcct gttgctcctg ttgctcccgt tgctccggtt
    53521 ggacctatta accctgttgc tcctgttatt cctattcctg ttgctcctgt tggacctgtt
    53581 gggcctgtca ctccaaatcc tgttgctcct gttgcccctg ttggacctgt tactccatct
    53641 gctcctgttg cccctgttgg acctgttact cctgttgctc cgtctgctcc tgttgctcct
    53701 gttggacctg ttggacctgt tattcctatt cctgttgctc ctactgctcc tgttgggcct
    53761 gtcgctccag gtgttcctgt tgctcctgtt ggacctatta atcctgttgc tcctgttact
    53821 cctactcctg ttgctcctgt tgggcctgtt ggacctgtta ctccaaatcc tgttgcccct
    53881 gttgctcctg ttggacctgt tattccatct gctcctgttg ctcccgttgg acctgttgga
    53941 cctgttactc catctgctcc tgttgctcct gtcgctcctg ttgggcctgt tggacctgtt
    54001 actccaaacc ctatagctcc tgttgggcct gttgcccctg ttgctcctgt tggacctctt
    54061 aatcctgttg ctcctgtatt ccctgtattt cctgttggac cagtcggacc ggttggtcct
    54121 gttgggcctg ttgcccctac tcctggacct gttggacccg ttggacctgt tgggccggtt
    54181 ctacctcttg gacccattgg gcctgttgga cctacacatg atggtggaca gcaatgatgg
    54241 caatcacagc tattataatc atcacgacca ttgttacaat catcatattt atcatagcca
    54301 ttgttgtaat cattatcatc aaatggtcca aaatatttat ttctactcat tattaaaagc
    54361 acctcctgat atatttgagc ttttaagctc tatatataat atgtcaaatt tagtatgatt
    54421 gtgacctatc aactattttt aaatttacta aaataatttt cattgtgcaa aacagcacta
    54481 tcgttaggtt tgatttcttt tgttttttca tgataataaa tagctttatc tgattctcct
    54541 aacctgtcat aacagacact taattgtata gatggtatat atccataaca atcatttgac
    54601 ttaaaacctc cattagtatc attcttatct cttgttaatg ctaccttata ccaaaaaatg
    54661 gcttctttat atttttgtct atcaaacata tgctttccta tgtcacaaca aatttctgct
    54721 cttggctcat caaattcgaa acttctaaac aatgaatata aggcactttt ttcatcatta
    54781 attaagtaat aacatgtggc taaatctctg caagcactga tacaatcctc aatccatcct
    54841 cttgatgagt ctaaaaactt agtaaaacct tctattgctt ctttatacct agcattatag
    54901 tacaactctc tagaataata gaattggtgt cttggctcca atgtttttcc ttctgaaatc
    54961 attttttcaa aaattctaag atttcttaga gggtcctgtc tatgaagctt tttatgagat
    55021 attgcaatgt cagaataaaa tacctctcca aaaagaggta ctacttcatg aatagggtca
    55081 acccatttat gattagaact tcttttaaac aatcgttctc tataatacga gagagttggg
    55141 ttaccatttt catcaaagga tacattgtat tttgccataa caatatcaat ggaagtatcc
    55201 aagctttctt taatctttaa taatttttct ctatcagctt ctaaaattat gtcatctgca
    55261 tcaagccaca tagtatagtc tttagaagct ttagaaaatg aaaaatttct tgcagcagag
    55321 aaatcatcta tccattcgaa atcgtacacc atgtctgtat attttgagac tatttctttt
    55381 gtggaatctg tagaacctgt atctacaatt ataatttcgt ctactatatc ctttacacat
    55441 tctaagcatc tgcctataac ttcttcctca ttcttaacaa tcatgcacaa acttattgta
    55501 atcataatgt acaactcctt tgtcttctat atattgcaga cataagtaat atatggtatt
    55561 ttctcttgtt ttgttattaa atttataaaa acttttgacg acagaaagtt actaaagaac
    55621 cttatctttt atgtattttt tatagtagaa tttattaaac ttgaaatttg gtaataattg
    55681 ttgaaatgat aaaaccatat ttaatttcat acaaaaaaga gtgtcccata aactaaaaag
    55741 ttcattttga gacactctta tttaatatta tatatatatt tgtaaaacag acattttaat
    55801 atgatacttt gatactttat tcattcctat tcattatata atcaatcagc ccgtactctt
    55861 tagcctctag tgcagtcata aaattatctc tatctgtatc tctcctaata tcttctattg
    55921 atttacctgt attttcagaa agaattttat ctaatcgttc ttttattttc aatatattat
    55981 ctacagctat ttttacatct gttgcttgac ctttagctcc tcccattggc tgatgaatca
    56041 taatctctga attaggtaaa gcacatcttt ttccatgtgt tcctcctgca agtaaaaaag
    56101 cactcatgct tgcagccata ccaatacaaa tagtcgatac atcacatctg acataattca
    56161 tagtatcata tatagcaaat cctgatgtag cagagccacc agggctattt atatatataa
    56221 ttatatctga atctgggtct tctgattcta aaaacagtaa ttgagctact actaaacttg
    56281 caatagcatc attaatttct tctcctataa atataattct atcttttaat aattttgaat
    56341 atatatcata agacctttcc ccttgacctg tttgttcaat tacatgtggc actaaactca
    56401 tgctactttc acctcacaat taatattaaa gttaagataa gaattgattt catctcttct
    56461 ttgtttataa ttcatatttg cataagaaat acatttttca ctttgaattt gatgatttag
    56521 atttaaaaca aatctctgtt gaataggata aaattcatct ttatttctat atacttgtgg
    56581 agattcttta tataaatttc taaatgctag tgtaaaagat tgatgtgtag aatatcctac
    56641 tgtaatagct atgtctataa tatatttgtc tgtaaatata agttgtctag ctgcttcagt
    56701 aagtctcctc ctctgtatgt attgatggat agtacatcct acaacatttg taaacattct
    56761 gtgtaaatgg tattttgaat aattagcaat ataagctatt ttatctaaat ttagattttc
    56821 tgtaagattt tcttctatat aatcaattat ctccataata acatctgtat ttgttttcaa
    56881 ctctatcctc tccttttaag tattataacc tatgcaaaaa gttttttctt aatataaatt
    56941 gctatcttaa tttagtgtat agcaataaag tatcgataaa aaaatatcag gtatttttat
    57001 acaaaaatat taatatatat ttcttttaaa gtttaaactt aattacatct attatatgta
    57061 gattgctaca tgttttatct atgtaccttg attcatatgt attattttgc tgagtatttt
    57121 tacacctttt tcaatttcat caaaactaag atgagcataa cctagtataa tttcatagtc
    57181 atattctaat atattctcaa ttgcatattg ttgtatagga taaactttta tacctgcttc
    57241 aaaaatttta tgaattaaac tttccgtaaa tttaacatta tagaaatgag caactatatg
    57301 aagccctgct gcttcacctt ttattttaaa ttcattttta aattccgtgt ttaaaacttt
    57361 tatgaggtac ttacgttttc tattgtacaa cttcttcatt ctaaatatgt acttctctaa
    57421 acctccattt ccaataaatt cagctaatac atgttgcaat attgtttctg tatgaacatc
    57481 agagtacatt tttaaggttt tatagctttc taaaatattg tctggtaata acataaatcc
    57541 aacacgaata gctggagata atattttact aaaagaacct atgtaaatta ctttatttgg
    57601 gctaagttca taaagagaac taattggttg accctcatat ctaaattcac tatcataatc
    57661 atcttcaatt atatagtaat cattctctgt tgcacattta ataagctcta gtcttctttg
    57721 aataggtaaa atccctccta atgggtattg atgagaaggt gtagtataaa caaaagaaat
    57781 cccctttatt gattttatta agttggtatt cattccctta tcatctactt taattccaac
    57841 aactgaatat ccaatagatg aaataacctt taataagcct ttatgaatag ggtcttctac
    57901 agcaaccttt ttattacttt tgtataaaag ctgtgaaatt aaagataaac cttgtgttga
    57961 accagaaaca atcataatgt ttttgggatt acatctaatt cctctagtac gaaataaata
    58021 cttagatatt tccactctta aaacccatac accagctgta cttccatatc tgaaatccga
    58081 atctgataaa tcatacagta tttgtttata tagctttgaa agttctttgc gtggaaatag
    58141 ttttaattct ggaactcctg aacgaaaatc tatataattt ttttgtttat tagtatgtaa
    58201 atctttttca tctctaaaag tatcatttaa cttaaaatca actttatgcc ctgatattcc
    58261 tttagctaca attgttccat atccattcct tgtttccaaa tatccttctg caattaattg
    58321 attatatgca tctaaaactg tattacgaga tacagatagt tcttttgata aagtcctaga
    58381 tgatggcagt ttttgctcaa actttaagct tccatccaga atcatatctt ttatctcaca
    58441 ataaatttgt cttgataatg atatattact atttctatta atcgtaatcc acattctaat
    58501 acctccaaaa gtggttctat aaaattacta taaaaatgga actataaaat ccacttttaa
    58561 tttgctaaga ttatatcata aaatataaaa taaaaaggag tctatattat gttagaggta
    58621 tcacataaag ttaaagaaat ttatcccaat attaaatttg gagttatggt tataaatatt
    58681 acacattcaa aacctaataa agaaaatttt ttagttctta aaaactctac aattaaaaat
    58741 attatagaac aacacccaga atacaatcgc aaagaaaaaa ttaaaacaga gcctgtttca
    58801 agttatataa agtattataa aaaattcaag aaaacttacc ctgtattgct tcaattagaa
    58861 tctattctat taaaatcaaa aggtatccca gatgtaggtg taacaattga gtcaatgttt
    58921 ttagcagaat tgaaaaatct tcttctaaca gcaggtcatg accttgataa aatggaatta
    58981 cctttgaaaa tagaattagc aaatggaagt gaacattttt atggtatagg tggtaaagaa
    59041 catattttaa caaaagatga tttattttta tcagataata ttggtatatt atctagtatt
    59101 cttaatggcc ctgataatcg aacagctata acaaaagata ctaaaaatat tatgtatttt
    59161 gtatatggac ctgataaaat atcagaaaag caaattcaag accatttaaa tgatataaaa
    59221 cactatattt caagtgcttt tccagattta aaagttaatt caattgatat attttagtta
    59281 atatattaaa atcctcataa atattttgaa taaataaatt agtgaagtat acattctagt
    59341 taaactagat atacttcact aaaattaatt atatgtagat attatttatt ttgaattttg
    59401 tttataacaa acactttatt acatttatcc tatgaataac ttaattttat aattaaagag
    59461 tttcataaga aacaatttca cttaaaggaa cacgagtttt ttcatgtctc tctgggctct
    59521 ctggtatctt agattcatat cccatcaata atatatttat tggttctaga ttatctggca
    59581 aactaaactc ttctctaatt atatctggat taaaatagca cacccaaaca cttgccaatc
    59641 caagttcagt tgcctgtaac atcatatggt ctgtaactat acttgtgtca atatctgtaa
    59701 gttgtttccc atcaaaaggt cttgtccaaa ctttgtcttt atctccacat acaagaattg
    59761 ctaatggcgc atcatatata ttggcagcct tagaaagttt atttatacct tctttttcct
    59821 gaataacaat caatctttga ggttgacgat taccaccagt tggagctatt cttgcaacat
    59881 ctaaaacctt ctcaagtttt tctttttcaa cctttctatc ttgataatta cggcaagaat
    59941 atcttttttt tgcaagttca acgaaattca tttatttacc ccctattgtt ttattaggct
    60001 aagttgatga tttatttaac ctatgctata attttatcac tatggtacta tattacaata
    60061 atgcactttt ttgtaatata gtacctaaaa agatacttta aaataaataa aggagcccaa
    60121 aaatgaaaaa atgtttagat aattacagtt gcccaataga agcaacactt gcattgattg
    60181 gtggtaaata taagacactt atactttggc atcttaaaga cactatattg aggttcaatg
    60241 aattaaaaaa attaattcct aaagcaacgc ctaagatgtt aactcaacaa ttacgtgaat
    60301 tagaatcaga tggtttaatt ataagagtgg tttatcctgt tgttcctcca aaagtagaat
    60361 actcgctatc tgattttgga aagagtatta ttccaatttt agattccatg tgtgactggg
    60421 gttctgatta cttagaaaat ctataaacca ttacagttta aatcccattg ctaatttaac
    60481 ttcatccatt tgttctttag atgtcaacat ttctaaaagc ttaaaagcta catgtggagc
    60541 tgtttctgga caatatgagg ttataatatt tttatctaca acaattggtt cattaactac
    60601 atttacatca aactcactta actgtctttg tcttttacca tttttcaaat gatatgtagt
    60661 agctttacga ttttttaaaa caccactttt tccaactggc aatgctgcca cacaaataga
    60721 agcgattatt ttttcttttg aattaaactc ccttattaga tttaaaaaag atgaatcata
    60781 tgcttcatca taaaatccaa attcttcaaa tcctccagga atagctagag catcataatc
    60841 atcaacacat acttcttcta tcgtcttatc aactaatact tgtatattaa atgtgctcat
    60901 aacttgtttt ttaaatccac aagtcactac atcaatatca tgcccataat cgttacgagc
    60961 ccatcccata acatctacaa atacactaaa ttccatagtt tcaaaacctt ttgctaaaaa
    61021 aactaaaact ttcatattct attttcctcc taaaatataa ttaacacttt actagtaaat
    61081 tatttaaaaa atatctttta ttgtattaaa ttcttcttta attgtagata aaacaatggt
    61141 tgtattagct ttttgaatcc ccccaatttc cttcaaagtc actgatataa actcttcaag
    61201 attacttgta tcttctgcta atacttttat taagtaatca tactctcctg aaatatgatg
    61261 acattctaat acagtatcat attccaatat agttttctta aattctttca tacttttaga
    61321 taaatcagta ttgataaata taaaagccaa aagcttatat tttgtttttt cccgattaat
    61381 ttgaatagtg tacttttgaa ttaaatttga ctgctcaatt ttccttatac gctctgagac
    61441 tgctggtact gataaattaa tttgtctgct tatttcagag gttgaagccc tactattctt
    61501 ttttagagaa ttaattattt ttaaatctat ttcatccaga gctactcacc tccttaatta
    61561 tttaatacaa ttttagctaa taatttacat taagtaaata aatttaatca tttcaataaa
    61621 atttaataca aatatgttat ttttccttaa aattttagtt ttctttaatc aaaacacata
    61681 taatacttaa aattatttaa gttgaattaa tgtttttatt ttgtataata tattagaacc
    61741 ttaatatatc attgaaaatt caacaataat agacatatac ttctacatgt tgtaatattt
    61801 atgaaaatag tatccctata tcaaaattat aaaactcata atcttaattt tcttatagac
    61861 tataaaattt tattgatagc gagtcttcaa ataactttgt aatgatagat ttactaaatt
    61921 aatataataa tagtaaatat aactttctta ttgactataa ctaagtatta tgataacata
    61981 acttaagcta taattaataa aacatatttt aaataaataa gataatccac aaagtacaaa
    62041 agtacaattt aaatacagat aaactagaat taatactaag attaggatgt gaataattat
    62101 gatttatata gaattagtta aacttgttag aaaacttaac tctacacaaa tgtatacgat
    62161 gaagcgttgt gtagaggtta atctgaaagc ttaaagcttt ctatcttcat cggcaaatat
    62221 aggtttagta tagttttttg gctatgctta tttaaaatta cctatttgcc gatagataat
    62281 atagattttc tggtcataga caacaatgct tgtctatgac cttttgtttt tccaaaagca
    62341 gaggtcggca ttttacaatg ccattcctct gcttttttta tttccataaa ttttttaata
    62401 aaagaaaagg agtttgaatt atgagtttat taaaagtaac taatttatca caatgtttta
    62461 tggataaatc actgtatgag aaagctaact ttgatttatt caaaggtgaa catataggtg
    62521 tagttggcca aaatggtaca ggtaaaagta cattaattaa aattttattg ggagaagttg
    62581 ttccagattc aggagaaatc aagtggcaac ctaatatcaa tataggccat ttagaccaat
    62641 atgcagaaat caatagagat acaacaatat cactctattt acacactgca tttgaagaac
    62701 tttataaaat agaaaaggaa atgaatttac tctatcaaaa aagtgctata tctgaaaatg
    62761 agcaatatct aatcaaagca tcagattatc aggaacaact aatagcaagt aatttctatt
    62821 ctatagataa tgaaataaat aaaatagcaa atggtcttgg attagattca ataggaatga
    62881 atcgtgttgt tagagagctt agtggtggtc aaagggcaaa ggtaatttta gcaaaattac
    62941 tactttctaa ccatgatgtt ctattattag acgaaccaac aaacttttta gataaagagc
    63001 atgttgaatg gctctcaaat tatttaaata catttaatgg ggcatttatt gtagtttccc
    63061 acgattttga ctttttagaa aaaatttcta caggtattct tgatatagaa tttggcatga
    63121 ttaagaaata tcatggaaaa tattcagagt tccttaaaca aaaatcacat ttaagagaag
    63181 attatattag aaggtatcaa gcacaacaaa agaaaataga aaaagaagaa acatttatac
    63241 gtaaaaataa agctggagta aattcaaaaa ttgcaagagg aagacaaaaa caattggata
    63301 aaatagaaag aatagctcct cctagtttta caggaaaacc aaatattcaa ttttcagaaa
    63361 ttgaaatatc ggctcaaaat gctcttacta taacaaatct tgaagttgga tactactatt
    63421 ctttacttcc aaaattaaat ttctctgttg atggaggtca aaaaatagtt ataactggtt
    63481 ttaatggaat cggtaaatct accttgttaa agacattagt caaagatatt cctcgtatat
    63541 ctggagattt ccagttttca gaacaagtta aaattggtta ttatgagcaa gatttaaaat
    63601 gggaaaatcc tgataaaacc ccacttcaaa tagtagcaga taaatatcca aaattaaata
    63661 caaaagagat tagacgtcat ctagccagat gtggtgtgaa ggaagagcat gtttcaagga
    63721 gtgtatctac tttaagtggt ggtgaacaat ctaaggttaa attatgttgt atgatgttat
    63781 ctccttgtaa ttttcttatt ctggatgaac caaccaatca ctttgatgca gagacaaagg
    63841 atgctttaca aaatgctttg aaacagttta gaggaagtat aatcctagtt tcccatgaag
    63901 aaaaatttta taaaggttgg attgataaag tatttaatat agaaaaacaa ttagtataag
    63961 tttatacaca atatacaata ttatttaatt ggtatttcaa tgcaaatttt aatgttctag
    64021 ttaatgtttc actgcaaata aactaaaaaa attttattag aacataaagt acattaccag
    64081 gatataaact taatgaggct atctcaaaat agagatagac ctcttcttca ttgttgagat
    64141 aacgaaaata catttgattt cacccataaa agaatgcctc attaactaaa aattcaactt
    64201 gagatatctt cattaatatt aaaatctatt ctaatcgatt ctattcacaa gtttatatcc
    64261 tagtccttta actgttataa gtattttagg atttgagggg ttatcttcaa ttttttctct
    64321 tatatgtcgt atatgcacca taattgtatt gtcacaaata ctactatata ctccccatac
    64381 ttgttcatag agtctttctt ttcctataat tttatttaca ttttgagcca tgtagcttaa
    64441 aagatgatac tcccttccag ttaactcaat ctcatttcta tctttatata cacggtttcc
    64501 ttctatatca atagtaatat ctcctatttt aataacttca ctatctgatg gtacaatgct
    64561 ttgatactgt tgtctacgta attgcgcttt aactcgaaaa gcaatttctc ttggactgaa
    64621 tggctttgtt atatagtcat ctcccccact actaagacct agtattttgt caatatcatc
    64681 attttttgat gataaaaaaa gaatagaaca gtatgaaaac tctcgaattt ttttacacac
    64741 ttctatacca tctatatctg gtaacattat atcaagaatg acaacatctg gacatgctat
    64801 cttacacagc gaaatagcat ctagaccatt ataagcttta ataatgtttt taaaaccatc
    64861 atttatgagt acttcttcaa ttaaatctac tatatccttt tcatcatcaa caagtaatat
    64921 ttttttatta aaacatgtat ccatattgaa atctctccat aaaaatttat tatattctaa
    64981 tcttgcagta tcactatctt gttttttata ttcactactc ttgcttttac attactaata
    65041 gtaacatctc taatagacaa attcaatcac tatgaaaatt aagataagtt tctttaaaat
    65101 aaagtgtatg atacattaaa acctatagaa aattaatttc atccaaagtt tataatatta
    65161 gactaataca cttacagata cagattaata caatagtaaa ataaaaggag ttgtcttaaa
    65221 attgactttt tctaatcaaa ctttaagttc aactcccttt taaactttta tatgttattt
    65281 ttattaattc tttatatcaa ttataacttt aattttcaat agtatatatc tcccactaat
    65341 tgaattactt attaaaacat aaaatatcta cctaaactat ttatttaata tctacatata
    65401 tttatatcta ttcttatact tacatataca aaaaatggtt aaaaataaag ttaaaatctc
    65461 agcacttggt actgctaacc atatcccatt tatatttaat atatttggca atatcaataa
    65521 acctatagtt ataaatccaa atgtacgtag aaaagataat attgcagaca cctttccatt
    65581 tgataatgct gtaaacatag acgaagtaaa aatattatac ccacaaaaaa taaaactaaa
    65641 agaaaatata taaaatccag accttgcaat ttcataaact cggcttcctc tttgagaaaa
    65701 aatctctaca atgattggtg aacatgatat agaaaagata aataccaata aagatgctac
    65761 tgaaataaat aatatacaaa tcttaaaaac atgatttaac tgcgtattat tttcacttcc
    65821 atagttataa cttattattg gtgcaacacc cattgagaaa cctatataaa gcgaagttaa
    65881 aagaaattga gaataaataa ttattgtaat agctgcaacc ccatcttcac caattaattt
    65941 catcatcata gcattaaata aaaaagtagt aactgctgtt gatagttgac tgaccatttc
    66001 agatgaacca ttaaaacaag cttcaaataa tattctttta tctagtctgg gtatacaaaa
    66061 cttaagtaac cctttgtttt ttgaaaagaa aaccatacct gaaacggtag gaattaggta
    66121 tcctactcca gttgcaagtg ctgctccact aatacccatt tgtaacagaa caatgaacac
    66181 atagtcaaga attatattag cacacccagc acctaacact agccataatc caaattgagg
    66241 ctttccagct gttacaaata aacattgaaa taatacttgt agtatatttg cagaagcaaa
    66301 aaccaagata ataaaaagat atgaacgaca atatttaatt aaaacttcac ttgctcctaa
    66361 ccatataatg atataatcca taaatacaat acctatacca gtaattatta caccaattac
    66421 aactcctgat aatacgatta aagaaaaagc tttatttgct ccctcaatat caccatttcc
    66481 catcttacgt gctacaatag cacttcctcc agtggcaagc atagttccaa ttccaactat
    66541 aagattaata attggacata caatattaat tgctgataga gcatttgtat taataaatct
    66601 tgatacaaat atagtatcta cgattgtata caaccccata aaaatcatca taaaaatagt
    66661 aggaaatgca aacttcaata gggtaaataa attaaatctt tgtgccagta aattatcttg
    66721 ctcataaaga ttatcttgtt catgattttc tgaataatat acatcactca ttttgtttat
    66781 ttttctgtac attaattatt tttaaaatat attccaaaca attagacatt tacagacctc
    66841 ctttctgcat aagaattata tctaattatt tggatatagt tttaattaat cttgcttttt
    66901 tacacaatta tatttctact aaagaaactt ttaaatcctt actttaataa ttttatagct
    66961 ttcagtgcct ttagcgcaaa tacttgttca catagtttag tgtcatatga aacatattta
    67021 tatatagtta tacattgtct atttttacta atttattaac tacttgcact tttataatgt
    67081 ctcataccta acttccaaaa tctccacata aacaatgtaa acaaaaatac aattaaaatt
    67141 gagtatatta atccattaat tgttattgtc ccagccaaaa tttgagtcgg aattgtcgac
    67201 ataattccat atggtaagat taaatagaat aatactttaa aaacaccttc atatattaca
    67261 ccaggaattt tcatattcat tggcaataaa ttatcttcta atctcattat cgcagaagat
    67321 gatataacaa aaaatgaaac tgttctaagt atgatacata catcataaaa aagtaatgtc
    67381 atcaataaca ccatgaaaat atatattatt atcatagcta aagttatctc tgagtttaac
    67441 tcagatattc catataaaac aataagtata cttgctagaa ttaatggtga tgaaccaata
    67501 ttaatatttt caaatgttaa cctaaatagt ggatctaatg gttttgtaat atagtagtct
    67561 aattctcctt cctggatttt tcgtggaata tcataaatac caaaaaagaa aatcgtcata
    67621 tttatcgcat ttattaatga gaaagttcct ataaatatta acatctctcc ttgtttccat
    67681 ccccctattg agtctacatg agaatatata ctattaaaca ttagaagttg taatataaat
    67741 aatgaactat ctacaaaaaa tgctccaaaa aaatcaaatc taaataccat catctttgat
    67801 aatttcattt ttaataacat aaatattatt ttcaaatttt ttttcatcat atacccaccc
    67861 catcaaataa tgttctcatt cttttataca taactttatt tactacagaa aaaaataaaa
    67921 cccataatgc tagaataatt aatccttgta ttgcctcatt gctgtttcta cctattagta
    67981 acatagatgg caaatatgtt gtataataaa atggaaatac cttcataact gttactatag
    68041 tttctggtaa gagtacaagt ggtatcattg ttcctgtaat aaattcaaca atattttcaa
    68101 ttatcattct aaaaaaacta atctcaagaa atttaaatga caaaatccca ataaagaagt
    68161 ggagtttcat cataaaaata aaccctagaa aaatcatcaa aattgaaatt aatatttgaa
    68221 ctggatttga tgtaaaggca aaatctattt taaatataaa aatccataca aatgcagaaa
    68281 tcatattaaa tacaaaataa aaacatgtca ttccaaaatt tttagcaata aaataatttt
    68341 gaacattaat tggaataatc atgtactttg aaaaggtgcc caattttaca cgattacata
    68401 tctcttcact ggtactcttt gacatatcaa tacctgctaa aaatgagctt attatatagt
    68461 aagataacat agagttaaat gtaaaaccag agactatttt attttcacca aaaattgctt
    68521 tccataaaat ataagcaaat aaaattttta caatcgtaaa caccatatta accaccacat
    68581 caaatctcca gataagttgc actttaaaat taattttggc tacttcataa taccttctaa
    68641 tactctgttt aaatttataa aacattgaat aatttgaact tgcttcatta tagttgctca
    68701 taatactcat cacttccttt cttatatatt ctctctacaa tactacctat atcttcttct
    68761 tcaatcatta catctttaac atcatattta tcaaaaatcc atttaatcgt ttcatttcct
    68821 ctttcttttg gcacaattac tgatgtctta tgatttgttt gttcaacaac tttacaatct
    68881 tttggaaata caatgttagt ttcattggaa aaactaactg ttattttttt atatttttga
    68941 aaataattaa ataatttctc tgtagaacca tcatatattt tacgactatt ttctacaaca
    69001 atacttctac tacagagact cttaatatct tccatgtaat gagaagtaag tataatagta
    69061 gttccttttg tttcatttac ttcttttagg aaatacctaa tttgtttttg ggctatagca
    69121 tctaagccta tagttggttc atccaaaaat aatatttttg gattatgtag aagggctact
    69181 attagttcca ttttcattct ttctcctaaa gaaagcgtcc taacttgaac atttaaatag
    69241 tcagatacct caaataattc gataaagtaa tccaagtttt ttttatattc ttcattagat
    69301 atatcatata attctttaaa taaaagaaac gtatctgctg gtgtcaattc aaagaatagt
    69361 tgactttttt ggcccataac aacagcatat tgttttttaa aattattttc taatttgtta
    69421 gggtaataac ccattacaga tatttctcca gaagacggtg caataatacc agttaacatc
    69481 ttaataagag tagttttgcc agctccattt tgacctatta atccaacaaa ttctccttct
    69541 tctatcttta aatcaaatga cgatatagct gttttttctg tatatttcct attaaataaa
    69601 gactttacac tccccataaa tcctgccttt ttctcaaatc ttctataaga tttagtcagt
    69661 tcattaagtt caattatact cattttaact acctccatat ttcataattt atataaaaaa
    69721 aagtccacag gtatatatct gcctttttct gtgcttatat ttaacagcac aaaaacagaa
    69781 aactcctgtg gactagaaaa attaatgctc tctatttcaa aataattatc aaaataatac
    69841 tatacaaaat taataaaagt gtagcagatt aaagcctact acaccataat ttaacaaagt
    69901 aatatatatt ttaaatacta tttgttgtca tatgtcagtt atctataaag gcagaataag
    69961 acacaaaaat taaatgtatt aaaaatacac ttgaaatttc tgattataca gaatatatgt
    70021 gtctccaact atttaattgt tggttaccat tatataactc cgacatcaag gcactcctct
    70081 cataatatta ttattgatat catatcataa aggttattta tgttcaagca tggatttata
    70141 tactaataca tttagcttat ttcttcaagg ttgaatttaa atttcattta taatattcgt
    70201 ttataaatta aaaatataat acgtatatta aaactggtca ttttactgta atatttttat
    70261 tgtaaaagat atacttttac ctatacagga tgtaatttct ttagttctat attataataa
    70321 tattgtaata agagttcaac ttataataca ttaaaatata aactgtaaat cttaaggggg
    70381 taatctatgg aaaataatac aatacaaaaa caattaagag atttatcaaa aaaaatttgg
    70441 catatttata ttttaaatcc agaagaagaa aaccttaaat ttattatttc cttattagat
    70501 gacaaccttg cattaattgg aacaggaaaa catgaatttt acgaaacatt agaagaattt
    70561 attataggtc ttgaaaaaga ccaaacagaa tcagagcaaa tagactttga gattatagat
    70621 gagtggtatt catgtaccaa agtcacagac gaagctttta tagtatatgg tactctttgg
    70681 gtaatagaaa aagattacct agaaaaagat atctatgtag aaatggatac tcgatttact
    70741 atggtataca gagttacaga tgatatgatt aaacttatcc atgttcacca ttctattcca
    70801 aactttgacc aaatgaaaga tgagtattac cctaaaacaa taactgaaaa agcacaagaa
    70861 gcactagcaa tggcaaatga atttaaacta aaatcagaaa aagaccttat gactggacta
    70921 tacaatagac atttttttga agtacacata aaaaaaatgc ttaaaactgt ttcacatgga
    70981 tacttttaca tctttgattt agataatttt aaacaggtaa atgatatctt tggtcatgtt
    71041 cgaggagatg aaatactaat acatttttca aatattttga ctaaagtatt cgtaaatgat
    71101 gctattattg gaagacttgg tggagatgaa tttgctgttt ttgaatatag taatcaatca
    71161 aaagagaatg ttgaaaataa ggcaaagaag gttttagaat tatgcctaga gagtaattct
    71221 tgttctatag gtatatctaa attagaaaat aactctgata ctttccagtc tttatacaaa
    71281 caatcggatt atgctttgta ttattcaaaa cgaaataata aaggaaactt tagttggttt
    71341 tagtacaaaa gatattaaaa taggcaaatt tattagagta tcttgtccta tatactaata
    71401 agtaaagtaa acaacaagct atctttgcat atatttatat aaaccaacta ttcttaataa
    71461 aactacaata gtcaacatga ccactattat agaatataat aaactaaaaa cattattaac
    71521 atgattaata ttatatttta ataattttat ttttaaaagt aagtccaaaa tgttatatgt
    71581 tttgattaaa actgatgttg atataaaaaa ttttacttaa aaaaacactt agaaaggctt
    71641 tataaagagc cttttttgct tttattgatt aaattttcat ataaaattcc ttattaaatt
    71701 tcaaatcaat aaaaaaaggc tctataagaa gcctccccct atttttattg attaaatcct
    71761 aatatagaca atgcctttgc atcatagtaa gtagtcatct ctcttgttgc atcctttaat
    71821 ttacggtaat caaagtctaa tgatccacca aaagctgata tttcagaccc atcaaaccta
    71881 taccatttcc catcaatttg tatatagttc caagcatgat ttaatgatgg atttaatata
    71941 gatagtgaat ccattcccat taaccttgtt aataaatgaa agctacttgc aaaacttcca
    72001 catacaccac gtttatcaac cagattacca tagactatgt tacaatattt agagtctgca
    72061 tattttgctt cggttaccaa ttttgcagct ctattagctc tttccatctc agatgcattt
    72121 ctccagtcaa aactatttaa aaaattcctt attactgtaa gtgtatcttg agcttgtttg
    72181 taagaaatcc aatttccatc agctattact tctatagggt caagttttcc aaagcctatt
    72241 ctctgatatg agccacctga caatgctgcc gcataaaatc ctagcccttc cataccctta
    72301 tttatataat aatatttacc atctgctcga agctcaactc cattgggatt tcctccatag
    72361 agtaaatccc atccctcttt acctgttgta ttaagaccaa gttgtgttaa cattccttta
    72421 agaggatatt tagggtcata attatcacct ttacttattg catttgtttg cactctgcca
    72481 tccattgtgc ctatattagt ctgattacgt tcatttgcac tctgtttttt caagctagat
    72541 gtttcatctt cttgatatgg ctctgccatt accgtcatac tcatcatcaa tataataatc
    72601 atggtaatca cagtagttaa tatattcttc ttcatactac tcccccttat ttaattcttt
    72661 ttaaaacata aaattattaa ctcataaata tatggttatt agtaaattga aattaagtct
    72721 gattcataaa ttattggttt aatagaagtg tattgaaatt gtacctttat attttcatta
    72781 tataataaac ttattttttt aaaacatatt gtttaaatca gtacatttat atgttttttt
    72841 tgttcatctg ttttatcaaa tatattagtc tttgaatttt gtttgtattc ttcagcattt
    72901 ttatctaact tttctattct cgactcaagt ttcattattt cttcttgtgt taaatttata
    72961 aaatttttaa gcatattttc aagctcttca cgagttttac ctactaaaga taagtcctca
    73021 gatactttct cttttttatt agaatccttt ttttgttcta actcttctaa tttttcatca
    73081 tttaatattt cttcttcaat tttttcatta gactctttag tgattaaaga ttctttttca
    73141 tcatttgtat ttagataagt tgaattttca tctaacattg tacttttatt tttatcttct
    73201 ataatgctat ttttaatacc tatttctata ttagaaaagt tattagttgt ttctcttatt
    73261 tctgatttac ataagttctt aattgcgtca tttatttttt tagtataaac ctcttgtcta
    73321 tattttaaat ctctaattct atcattaagt tcttgctttt gtttcataat attagataaa
    73381 taagtgtctt ttcctacagt ttcatttttc ttaaccatac tttcatttat tcttgtatta
    73441 tttatattac tttcatatct aaatgaatat tgacttctat attgactaga tattttcatt
    73501 tatttcacct ccttaaaata aatttatgtt tataaaaacc aacttaactt aattatattt
    73561 tatcatcaaa agtatacatt tacaaatatt agttaatagt tttataggtt cgagcattat
    73621 tttcaacaaa aaatttttat tataaattaa aacaataatt tttataaata tattatttgt
    73681 attttataat tcatatattt ttactttata aattagcaat attgcagttt tgctcttaag
    73741 aaacatctct atcatacata agcatatact ctattatgta ttagtataaa tatgcctttt
    73801 cttatcttac ataagacctc tttataaagg agcctatcgt aacaaatatg tatacattat
    73861 cacatgtata tatcatcata taaaaaatca aactttatta aaaaaattaa taaattgctt
    73921 taaataatac cacaaaccaa atttgccatc aaaatcacat taaagtaaca aattgatggc
    73981 aaatttaata tattaatagt atatagactc atagaatgaa caaaaaaact acacttatct
    74041 tctaatcgtc ttatttattt ttgagatatt tttaaatttc ttttcttttt ttgctaagta
    74101 ttcgctttta ttgtctgcaa atactgcttc agctttaagc ctacgatagg actcccatct
    74161 tttaggcgaa agttcttgat gagcaatagc ttcccagata gcacagcctg gttctgaggt
    74221 gtgagtacaa ttacgaaaat gacattttcc gaaataagct tctatatctg caaaactttt
    74281 atctaaacct tctgaaacat cccacattcc caactctctc atacctggtg tgtcaataac
    74341 aataccacca cctgaaatta aaaatagctc tcgtctagtc gtggcatgtc ttcctttatc
    74401 atcatctatg cgaatttcct ttgtatttaa aaattctcca cccatcagac aattaattaa
    74461 tgaagatttt ccaactcctg aagaaccaag taaggcaaca gtacagcctg gtttaatata
    74521 cttagaaatc tgtttataac catctggctc tatagatgag gtaacaacta catctacacc
    74581 caaggctata gaattaacta cttgtaattt acgatgcaca ttgtcacata agtctgattt
    74641 agtaagtact actactggga tagctccact ttcccatgtt aaagacagat acctctccaa
    74701 tctatgaatg ttaaaatcct tattcagtga catgcacaaa aaaacaatgt caatattagc
    74761 tgcaactacc tgctcctcat ttacctttcc agcagcctta cgcacaaaca agctttttct
    74821 atgaagcaca tgatgaataa tagcattacc atttttatta ttgcaacgat ccaacataac
    74881 gaaatcacca actgtgggaa aatcagattg tatagtagcc tcaaaacgca gctttcctga
    74941 aacctctgca aacagtacac catttacaca tacagcttga taaaagttct tttcctgcga
    75001 gataatccga gcaaggtata aatcataata ttccatactt tgagtaataa aattcctatt
    75061 tagaccatag tcttgtaaat tgatttgttt cataccattc attctgtttc ctccttttcc
    75121 aacttttcaa tgattctttc tagtgggaaa gggggctgtg ccagtggttt taatgcaatt
    75181 gacattaatt tcactgaatt atcatcagct gcaatacgat tagaactaag atgtccacag
    75241 cgtgtacaac gatgaataat tgcccactca ccattttttc tcacccacac tccaataggt
    75301 tccatattag catcacaatc tgcagcacgg tcaccaggaa tgatatctac atgaagacta
    75361 tgtaaacaat gtgggcaatg atttctatgt tgtgtaccag ctccttcagg aactacaagg
    75421 caaccacaat ttttgcaaat aaagttatcc atacaggaat tttcctgata ataagctcgt
    75481 tttctatttt tataattcat ttttatttcc tccgtatctt gtattttcta caaaaaaagt
    75541 ccacaggtat ttatatctgc ctttttatgt ggtatacata tttacctaca caaaaacaga
    75601 aaacccctgt ggactagaaa atttaatatc ttctatttca acataattat attcaaaata
    75661 atactgtgta aaattaataa aagtgtagca gattaaatcc cactacacca caatttaaca
    75721 aagtaatatg taatattatt atttgttgtc taatgttagt tatctataaa ggcagagtaa
    75781 gacacaacaa tcaaatgtat caaaaataca cttaaaaatt ctgattaaac agaacccata
    75841 tgcgtctcca actatttatt tgttggttac cattatatat aactctgaca tcaggcaaga
    75901 cactccttca ctaataatta ttattgaaat tttatcataa aatataagta tgttcaagta
    75961 taatttaata tattcatata tttatgtttg tctcattttc ttattctata aaatctagtg
    76021 gtattttaaa atttaatgtt cacctagtat taataataaa aattaactgc tattatttgt
    76081 tttctcattt tatgcctatt gctcaattta tctcacttaa attaataaca actgtctttt
    76141 catacaaaac ctacaatcaa gtttttccat atattctaca tgcatagtct atttttttga
    76201 tataaaataa cgttcatatt tgtaaattta tttaattttc aaataagtat attgaataat
    76261 aagcaattct attgtattat tgtaattgta gaataaaact aaatcggcaa aactagagaa
    76321 atttagtgac gcaaagctat agggactaac gcttataaaa taaactatga gttatgtcag
    76381 ccagttgcca aaaagagata ttctttttgt ttttatgaaa gttttttagg gggataataa
    76441 tatatatgtt tagagataaa atggatagat gtacacatat gttgactgct tatattggta
    76501 gttcatatga ttattgtgat tttatagata cacaactaga tgattttata ctagagtacg
    76561 gagaaaatgt ggtagaatct tgtttgcatc aagtgatggt attagtaagt aagtataatt
    76621 aaatagattt ggttttctag agaacccttt ttagttttat ctactttaaa tagccttatg
    76681 ttagaaagct aattaagata gatttctagt attcataatt ttatttttta tttaaaatac
    76741 atataataaa gatgtaaatt tgtatcaaat aataaatatg agaacttaaa ttctcttatc
    76801 tatgtgaaaa taaacatctc ttaaaatgaa attctgtaaa cataaatgat tttttagttt
    76861 gaaggattag attaacaaaa ttataaattt gcaaataagc tatattaaaa aatataataa
    76921 ttttttatat aacttattct tttataactt ttaattttaa aagaggagaa tgtatataag
    76981 agtattcaat gtactagaaa aaatcaaaag aaatattaga agaaatggat attgagtaat
    77041 caaagaaaag attttgatat tacaaatgat atgtttcaag aaagcattcc tatcacaaca
    77101 aaaattattc ttgaagacat gccttcaaat gatgaattaa atcatgtttt ttcaaaaggt
    77161 tgtgaacgaa aaatgaaaaa gagaaaaatt gtattaatca cactactatt aataggtgtt
    77221 ttgttattag gaagtatcct atataatctt tttttaggaa aaacagctaa tatttcaatg
    77281 ctaaaggaat cttggaattt tgatatacca atacctaaca aagaaattga agtatttgat
    77341 actcaagata gtattaatgg agatggacaa agttatttta ttcaaggatt ttctgaaaaa
    77401 aatttcaaaa aagtttttaa tttaaaaggt ggtatagttg taagcaaaga taatattaat
    77461 gaaatagaaa aatatattga taaatttaaa agagattctg ttaacattaa taaaagtaat
    77521 aaaaataaaa ttgaagaaga ttttaaaaaa tataagttag aagttaaaaa agatgataag
    77581 tatatatata agagaaatta tgagaactac gtagttttaa ttataaaaaa agatgaacaa
    77641 aaattataca gtttaatatg gaatcagtag gtacatatgt attattaaga attataaata
    77701 ataaaaataa attttagtca atatacaaaa accttttaaa ttgtctggaa atcacctctt
    77761 catttgttat aaaaacatac aacaaatgaa gaggtgattt tatggtttta aaaaaaataa
    77821 ttataagtgg atatgtgctt tcacatgttt atcaacattt gtaatgccta tatttgctaa
    77881 tgaattataa tataaaaata ttaaataata ttcaactata gattatgtaa attactctat
    77941 gaaaaaaata agttgtataa aatctggcta ctgtagattg acgatttctt ttaaaattac
    78001 aattataata agttttatag aattaaaaat aaaactttag agatttttga taacattgta
    78061 gactaaattt gccaccaaaa tcgctttaca gtggcaaatc ggtggcaaat acaatatatt
    78121 attagtatat aatctatata aacattacta ttgtttgatt atcttagcta cagtttccac
    78181 atgtgtagaa tgagggaaca tatctacagg ttgtgcctca acacatttaa atccgtgaac
    78241 atttagataa tctaaatccc ttgctaaagt agaaggatta caagaaacat agacaattct
    78301 ttccggattc attgaaacaa tagtctctaa taccttttcg tcacatccct ttctaggtgg
    78361 gtctacaact actacattgg cagtcttacc ctctctatac atcttaggta caatttcctc
    78421 tgcctttcca acataaaatt cagcattatg tatattgttt aatttagcat ttattttagc
    78481 atcttttatg gcatcatcta taatttctat tccataaacc tttttagcct tttgtgccaa
    78541 aaataaagat attgtaccta tcccacagta aatatcaaaa acagtatcag tatcatttaa
    78601 atttgcatat tcaagagcct tatcatacaa tactttagtt tggacagggt ttacttggaa
    78661 aaatgataat ggtgaaatct caaacactaa gtcacctata taatcgttta tttttccatc
    78721 tccatatata actatatttt ctcttcctag aatagcattc gtatcttttt gatttacatt
    78781 tacaaccaaa gtcttaaatc caggtatatt ttccttaagc actgaagcta attctttaag
    78841 atatggaagt ttgtttccat ttgctactaa tacaaccatt acttctttag ttgtaaaacc
    78901 tatttttgtt actaaatgcc taatcaaccc cgtgtgagtc ttttcatcat atatacttac
    78961 cttataggcc cttatatatg tttttattat tttaacaatt ttatcattta tctcatgttg
    79021 tattacgcat ttttctgtcg atattacatc atgagtcttc tttttataga agccaataat
    79081 tggaatacca ttattctttt gtattggaaa ttgtgcttta tttctatatc tatatggatt
    79141 atccattcct atagtgtcat gaacttctac atcctctaac ttacctattc tcgaaagtac
    79201 ttgtttaact tcatttgttt tcatttcaag ttgtttatta taatctaagt cttgtatctg
    79261 acaccctcca caatccctaa gattgtcact acacactctt ttcaccctga atggagactt
    79321 ttctattatc tcaacaatat ctcccacagc ataatttttc tttactttat taatcctaac
    79381 tttaacttta tcatgtatta atccgccctc tacaaaaact gtaataccat tgtactttcc
    79441 tactcctact ccgccttgac caatgtctac tatatctaca atatacatct cgtttttcga
    79501 aagcataaat caccctccaa tcaatctatt atatttaaat ctttacaaac ttttttcttt
    79561 aaatttatat taaaatattg ctattaatta aactatattt tttactaagc tacaatattt
    79621 tattttacca aaaaaaaagg agcttataaa gccccttagt aaataaattt attatttttc
    79681 ttataaaact ctagttgaac ctctatatac cacgcctctt gatgcatcca cagttacaac
    79741 ttctccatct tttactagat ttgttatatc agctgcagac acaataactg gtatatctaa
    79801 atttatacct acaatagctg tatgtgatgt cattccacca ttctcagtta ctacagctcc
    79861 tgctttttct atataattgt tcatttcagc atcagtagca gtagaaacaa gtatgtcgcc
    79921 ttcattaaag tctacacaag catttccatt ctttattata cgaactttac cttctaccgt
    79981 ttgagtacct acacctatac cttgcacgat ttcttcgctt attacatgaa cctttattaa
    80041 attagtagtt ccacttactc ctactggtac tccagcagtt ataactacta attccccatt
    80101 atctatataa tcagcttgtc tagctgcctc aattgccttt tctataactt catctgtatt
    80161 tcctgcaaca gaagacttaa ctggatatac tccccatgta agagctaatt tattcatagt
    80221 cttttcatta tttgtagtag ctattattgg agattttggt ctaaatttag ataccattct
    80281 agcagtatat cctgaagaag tagatgttat tatagctgat gcatttaaat ctactgctgt
    80341 tgtacaagtt gcatggctta ttgcatctgt tacagtaaca ttgttagtac cattttcctt
    80401 tagtaatcta tcataatcta aagtctcttc tgttcttttt gctattgtag ccatcatttt
    80461 tactgcctct acaggatatt ttccagcagc agtttctcca gataacatta tcgcatctgt
    80521 tccatcatat atagcattgg caacgtctgt aacttctgct cttgttggtc ttggatttct
    80581 tatcatagaa tcaagcattt gagtggcagt aacaactggc tttgctaatt cattacattt
    80641 ttttatcatc attttttgaa ctattggcat ctcttcagtt ggtatctcaa cacctaagtc
    80701 acctctagcc accattatac catcagaaac ttttaatatt tcatctaggt tctctacacc
    80761 ttcttggttt tctattttag atattatttg tatatcagtt gcattattgt tctctaatac
    80821 ttctcttatt gctagtacat cagatgcctt tcttacaaaa gaagcagcta tataatctat
    80881 tccttgactt attccaaact ctatatcact tatatcttta ggagttattg ctggtaaatt
    80941 tatcttaaca ccaggtacat ttactccttt atgattttta actattcctg aattttcaac
    81001 aacacaaact atatcttctc catttatttc ttttactctt aagccaacta aaccatcatc
    81061 tattagtata gaatctcctg atttaacgtc ttcagcaaga cctttatagc ttactgtaca
    81121 catttcttta gtccccataa tatctttcat agttatagtg aacttttgcc cttcttctaa
    81181 aaatacctct gggtcttcaa agttacctgt tctaatttct ggacctttag tatctaataa
    81241 tatagcaact ggcttattta atttttctct aactttcttt gccatatcaa ttctttcttt
    81301 atgttcttca tgcgaaccgt gagaaaagtt aaatctacac acatttagac cattttgcat
    81361 aagttgagtt aaaacttcct cactttgtga tgctggacct agtgtacaaa caatttttgt
    81421 cttctttaca ttatttaaca tatttgctcc tcctgagata ttattccaca gatttatttt
    81481 taatactaaa acttatatag ataatatttt tgccatctca taagcttctt tatcaaatac
    81541 tttcttttga gctaaagctt cacttatttc taaatcaatt attttgtttt cttttattcc
    81601 tacaactcta gctgattttc catctaataa taattctact gctcttactc caagtctact
    81661 tgctagtatt ctatcagata cagttgggct tcctcctctt tggacatgcc ccaatacagt
    81721 gactcttaaa tctgctcctg actctttttt aagttccttt tctaaatcac tagcacttcc
    81781 gactccttct gctaaaacga ttatactatg tctcttacct cttttttgag tagtctttaa
    81841 tcttagagca acttcatcta ctgtaatttc tacttctggt actattatag tttccgctcc
    81901 tcctgcaaga cctgcatata aggctaaatc tccacagtgt cttcccataa cttctactat
    81961 gttaactctt tcatgagatg atgatgtatc tcttatctta cctatagcat ctataatagt
    82021 attcattgca gtatcaaatc ctatagtata atctgtatat gctaaatcgt tatctatagt
    82081 tcctggtatg cctatagctg ggaatcctaa gtcactaagt ttttgggctc ctgcaaatga
    82141 accatctcca ccaattacaa ctaagcaatc aattttatac tttttaagaa tttttactgc
    82201 ttttaatcta ccttcttctg ttttaaattc ttcacatctg gaagatttta atatagttcc
    82261 tcccctgtgt ataatatctc caacagaaga taagttcatt tcagttaaat cttcttctag
    82321 taatccctta tatcctctat tgattccata tactttgcat ccataatata ttgctgatct
    82381 tacaaccgct ctaatcgcag cattcattcc tggagcatct cctccacttg ttagtaatcc
    82441 tatagttttc attttttacc tccttggatt ttatgtcaat tttttattat aatcattgtt
    82501 attgtattct aatggacttt ttttgtccct atatcacttt ttaatcccat caagactaaa
    82561 aaaattaaat gtccttaaat gtccattttg tgatattata tcacaaaacg gacaatattt
    82621 ttcatattat tataatatat ttagattttt atataaaaaa tcaagctttt acttttatgt
    82681 tatctttagg aagtaactct tctaagttat ttataaattc atcacatata caagtcaatg
    82741 ccccggtcat tttatatgct ttacgtttac catttatatt ttcatccata gggtacaagt
    82801 atatactgtc attacctgga tattgtttgg ctatttctac aatattatta gttgtatcag
    82861 tatcagacat actatctatt ttcaaataca attttttacc actttctggc ttaatatttt
    82921 ctacatttct agttcttcct gaattgtagt ttctatctgc aaagtcagta tcatcattta
    82981 tatcttttat ctctctagct ataagttttg cattttcgcc ttcttttata cttaatgttc
    83041 cttttacata tattatatta tcttcattca aaatgacatt atacttttgt aataattgag
    83101 gaaaaactat tatttctata gcaccataca aatcttctaa ttcaataaat gccataattt
    83161 catttcgttt tgttgtttta atagttttag ttacaatcat tccacccatt ataacatctg
    83221 tttcattcat ttgtaggtat gactcttctt cctcttttaa tgaatttaat tttccattat
    83281 ccatagatgt tttttcttgt agttcttttt caaattgtga taaaggatgt ccacttacat
    83341 acattcccaa gacttctttt tcaaggttaa gtctctctct ttcttcgtac tcttgccttt
    83401 taggcaaact gtatatttgt tgaaaatcac tatcttcctc actatctcca aaagcatcaa
    83461 ataaagaaat ttgaccttga acatttttct ttctatccat agatacactt tctaataaac
    83521 tttcataacc agccatcaga ctagctctat tttcacttat attatcaaaa gctccacatt
    83581 ttattagact ttctattact ctcttatttg tatctttttg gtctaatctt ttgactaaat
    83641 ctactaaatc tacaaataat ccattagatt ctctttcagc gattatattg tttattatat
    83701 ttacgccaac attttttacg gctgctagac caaatcttat attgtcgcct tcaactgaaa
    83761 actttgaaaa acttttgttt atatctggag gtaatacatc tatttctagt gctttacatt
    83821 ctcttatata ctcaactacc ttatcagtat ttcccattac actggttatc aatgctgcca
    83881 taaattcaac tggataatat gtttttagat aagctgtctc atatgctaaa accccatatg
    83941 cagctgcatg tgatttatta aatgcatatc tagcgaagtc tatcatatca tcaaatattt
    84001 tattagctat ttcctcttct acaccatttc tgatacaccc tgcaatttct atattaccat
    84061 cttcatcaaa tttaccatga ataaaatatt gtctttcttc ttccatcacg tccatctttt
    84121 tcttactcat ggctcttcta actaggtcac ttcgtccgta actataacca cctaaatctc
    84181 taacgacctg cataacctgc tcttgatata ccaaacaacc atatgtaact tccattatag
    84241 gctttaattt ttcatgtaga tatgttacat cttttgggtt gcttttattt tttatatatg
    84301 caggtataga atccattgga cctggtctaa atagggatat tcccgctaca atatcttcaa
    84361 aattgtctgg ttttagctgt ttcataaaac ttctcatgcc agcactctcc aattgaaaca
    84421 cccctagtgt atttcctgat gaaagcattt catatacttt agggtcgtca taatccatct
    84481 ttgaaaagtc tattttttct gtgtagtttt ttataactct atttttttct attaaatcaa
    84541 gagtatctct tataactgta agagttctta gcccaagaaa atccatcttt aaaagcccaa
    84601 gttcttcaag tgttgtcata gtaaactgtg ttgtgattgc atcttgatgt ttgtacaaag
    84661 gtacatattc atctacggga ttttttgata taacaactcc tgctgcatga gtagaagcat
    84721 gtcttagcat tccctctatc tgttttgata tatttattat ttcttttgtt tccgggtctt
    84781 ggtcatacaa ttctttaaga ttaggatttg tatctagggc cttatctatt gtcattccta
    84841 aagcaaatgg tatttccttg gctaccttgt caactttatt gtagcctata tccaataccc
    84901 ttccaacatc tcttattgca gcttttgcac ccattgttcc aaaagttatt atctgggcta
    84961 catggtcatc accatatttt ctctttacat aatctataac ttcttctctt ctctcataac
    85021 aaaaatctat atctatatct ggcatggata tacgttctgg atttaaaaaa cgctcaaata
    85081 atagagagta ctttattggg tctatatcag ttattttaag tgtatatgct actatcgaac
    85141 cagccgcact acctctacct ggtcctacta taatattatt ttctttagaa aaatttataa
    85201 aatcccaaac aattaaaaaa tattctacat aacccatttt ttcaattaca tctaattcat
    85261 aatttaatct ctctagtatc tcattgctag gattatcata tctctctttt aatccattaa
    85321 aacacaactc ccttaaataa gtttctggtg tatatccttc tggaacatca tacttaggaa
    85381 gatgtatagt gttaaaatca aactccacat tacacatatc agctattttc acagtattat
    85441 caatagcctc taatgcatat ggaaataatt cttccatttc ttctcttgat tttaaataaa
    85501 actcatcact accaaatctc attctatttg ggtcatttaa tgtttttccc atttgaatac
    85561 acataagtac atcatgtatt ttcgaatctt ctttatttac atagtgaaca tcattagtag
    85621 caactagtgg tataccagtc tcttttgata attttactaa accagagttt acttcttttt
    85681 gctcaggtaa attgtgatct tgaatctcca aaaagaaatt ttcttctcca aatatgtctc
    85741 tatagtcaag agcaaattgt tttgcttttt cataatttct attcattaaa gcacgtgcta
    85801 catctcctgc aaggcatgca gaaagtgcta taatcccttt gttatgcttt ttaagttctt
    85861 ccatgtcaac tctaggctta tagtaaaaac cttctacgta tgaagttgaa actattttta
    85921 ttaaattttt atatccttcc atattcttag ctaacagaac taaatgtcct tgatatttgt
    85981 catagtttgg gtctttatct ctcaatccac gtgcagctgt atagacttcg caccctataa
    86041 ttggctttat tccttctttt atagctgttt tgtagaaatc tataacacca aacatacaac
    86101 catggtcagt tatagctatt gagctcatgt ttagttcctt agcccttttt ataagttttt
    86161 tcaccctcga aaacccatca agtaaactat actcagtatg tacatgaaga tgagcaaaat
    86221 ctttgttcat taaatcacct cctgctttat aattttaatt ttaccacaaa tatatgtact
    86281 aaaacaaaaa cagagacttt tatctcaaaa taggaattaa cttcaacgta taccattata
    86341 tgttataaat taatgcttat tctgagattg tcccctcaat ttattgctat gatttttttt
    86401 tcaaatctgt tgcaatttct tctatttttc taagtctatg attgactcca gattttccta
    86461 ttggtggttc taacatctct ccaagttctt tgagagtcat atcctcatac tcgattctaa
    86521 tcttagctat ctcttgtaaa ttttctggca aactgctaat tcctatagtc tcttgtatga
    86581 gcttaatatt ttctacttgt cttactgctg catttactgt tttagaaagg ttagctgtct
    86641 cacaatttac tatcctgttt acattatttc tcatttcttt tactatttta gtattttgaa
    86701 gacttaaaag agcgtggtgt cctcctataa tactcaacaa atctgatatt tgttcactct
    86761 ctttgatata aacaacgtga ttattttttc tagccacaat tttactatta aaacctaaag
    86821 agtttataag ttcttttaga gaatctgcaa actcctcatt attagttaca aattccatat
    86881 gatagttctt ttctgggtca cttatagaac ctccaccaag aaaagctcct cttatgaaag
    86941 ctctcttaca tccttcatgc ttaattaagt tctctgaaat tttgtttata gtaaaaaatc
    87001 cttctttatc ttcaagtata cctaactttt ttaataacat ttctgaaccc atttcgcttg
    87061 ttaccattaa tacataactg ttatttctct ttagcatttg attcttattt actgagattg
    87121 tagtattgat attaaaattc ttttttaata atttaaatac tttacgggct attgaattta
    87181 actctgttgt tatctttaga tttagcttct tatatccaac aatttgtata cttccccctg
    87241 atttaactag agctgacaat tcagctatat tacaacattc attcccagat ataactcttg
    87301 ctagttcatt tttggtttca gttgaaaaag acatatctat cacctattaa ctaatttttc
    87361 tttaaccttt tttttatttc ttgtaaggca acctttatta tctccttttc atcatcatac
    87421 ctagctaagt ctactactct atctaggtgg ataaatttag catcaataaa gccttcctct
    87481 ttttgtggaa tagtatccat attctttgct tgcatcaaat accaaaaaac tgttttatga
    87541 actgctctat tttcatccca gttttctttg aatgtatagt gtatttcacc taaatatttc
    87601 aatatatctg cttttactcc agtttcttca cttacttcac gtaatgctgc ctcttggtta
    87661 ttttcccctt cttctacttt tcccttgggt aacacccaat ctccattgaa cttccttagt
    87721 aaaagaatcg tattgccaaa caggactaca ccaccagcac taacctcttc tctcatcgat
    87781 gttcactcct taaaactaac ataatgataa ggatttctac acaatttttt aaaatccttt
    87841 tttactaact tttgttgtaa ttatgattta gggctaactc aataactatg ttagatatat
    87901 actttgcatc atgtcttata taattatttt ttatttcaat taaattcttc tctacagttt
    87961 ttatacccat ctcttttaat ttatcttttt gctttttatc taacaagact tgctctgctc
    88021 catcttgttt atataagtca agcatttctt ctggcaatat ctcattattt gcgattacat
    88081 aatctattaa attctcatca gtgtgtttta ctatagcatt aacatgctct aatacattat
    88141 acccttctgt ctcacctggt tgagtcatta tatttgctat atatactttt ggagctacag
    88201 acgatttaat agcgtctaca atcccctcta caagtaaatt gggtattata cttgtatata
    88261 aacttccagg acccataatt ataatgtcag catcataaat agatgcaata acatccttta
    88321 atggttttac atcttttgga tttaaaaaaa ttttatcaat agagcttttt tgaatttttg
    88381 actcttcagg tatactagat tctccattta ttatattgcc attttctaat ttggcaacta
    88441 aatttacatc ttccaaagtt actggtaaaa ctcttcctgt tatagcaaaa atttcactta
    88501 atttatatac agctttttca aagtttccat acaacccatt catagcagcc aaaaacaaat
    88561 ttccaaaact ctgacctttt aaaagccctt ctgtaaacct atattgcata acttcattca
    88621 ttgttggctc tatatttgca agtgctaata aacagtttct tatgtctcct ggtgggagca
    88681 ttcctaagtc ttctctcaat acacctgaac ctccaccatc atcagcaaca gttacaattg
    88741 cagttatatt ttgcgtagtg tgtttaagac ctcttaaaaa taccgattga ccagtacctc
    88801 cacctatcac aaccacattt ggttctctat tttcaacaat agacctttga aatagtttta
    88861 ctttttcatt ttttgctttt ttatatataa ataacgatac aattaatgca atccaaccta
    88921 aaattcctac aataataagt aatttagcca tgtttgcctc cattatcgca acatagagtc
    88981 tctatgtttc tttacaactc tatatccctt attagataaa tcctccgcta taagatttgt
    89041 tatagtaact gacctatgtc ttccacctgt gcatccaaca ccaattacta gatgttgttt
    89101 tccttcctct atatattgag gtactaaaaa atgaatcata tctaaaagtt tcacataaaa
    89161 ttcttcactg attttagaat tcataacata atctctaact tctttatcat caccagtttt
    89221 agctcttaac tcttcaacat aatagggatt tggaagaaat cttacatcaa atactaaatc
    89281 tgcatcagca agtataccat gtttaaatcc aaaagatact acagaaatag ttaggtttgg
    89341 attatcttca ccagaagaat atattttctt tatttcttcc ttaaggtctt taggtttcat
    89401 gttagttgta tcaattatac atgtagataa ctcctttaaa ggttccatta tctttctttc
    89461 catttttata ccttctggaa tctgcatatc ttttgccaat ggatgatttc ttcttgtcat
    89521 tttatatctc tttaacaata catcatcatt acaatccaaa tataccattt catattcata
    89581 attttctttt tctaaataat ttaagctttc atgaagcgct tcaaaaaact ttctccctct
    89641 tatatctatc cctagagcaa ctttatcaat acttgaattt ggttgataac ataattctgc
    89701 aaatttagtt atcaaagcag gaggtagatt atctacacaa taaaatccca tatcctctaa
    89761 agctctcatt gtctcacttt ttccagatcc tgaaagacct gtaactataa caaatttcat
    89821 tgctaactcc tcccttttat cttatgttta ttatattata atgttttcta ctaacgatat
    89881 atccagatta gagtcagata tagtcttcat agctagttca aaatcaccaa ctctttctgg
    89941 acaatgtgca tctgagccta ttataaattt attttctagc ccttttattt tatttaattg
    90001 atttacattc aaaaaagaat ggctactatt tatctcaagt ctagtatttg tcttttttgc
    90061 tgtctttgct acttcttcta tatacacatc gcctttatct cctggatgag taattataaa
    90121 aatatcatta ttacttatcg catttattac agcttttgta ttatattctt ttgctttttc
    90181 agttttaaaa atatagttat tacaatgatt taataagctt cttaatgatg ttggagtaga
    90241 accaaaatga tatccagcca taatataatc aaaatctcta ataaatttat catccatatc
    90301 tatatttcct ttatcatcta atatgttaca ctccatacct aaaagtatat ttatatcagt
    90361 gtacttatca tttaaataat ctacttcttc tctcattttg agaatatctt ttttctttac
    90421 accatatgca atatgtttat aactatggtc agatattcct attgttttta ttcctttaga
    90481 aatggctacc tttacattat cctcaatagt ccctttgcca tgactatata atgtatgtgt
    90541 atgataatca gccagtattt tcatttgtta atcctctcca agtattttga cttcttcttc
    90601 caacataacc ccaaacttgg catatacagc actttttata acatatatta aatccaaaat
    90661 atctttagca cttgcttctc cttgattgac tacaaatcca caatgcttct cagatacttg
    90721 tgctcctctt aaagtaagac ctctcaatcc agtttcttct attaatttac ctgcaaaata
    90781 tcctgttggt ctcttaaatg tacttcctgc actagcaaaa tttaatggtt gtttagttat
    90841 tcttctcgtc gctaaatcat ccattaaact ttttatttca tcataatttc cttcttgtaa
    90901 ttctaattct gctgataaag ctatatatcc gtttttcgat attatacttt ttctataccc
    90961 aaattccatc tgttcatttg ataattcaaa tatattgcct tccatatcca tcagtcttac
    91021 tgacttcact atgtccttca tttcaccacc atatgctcca gcattcatgg ctaatgctcc
    91081 tcccaatgtg ccaggtattc ctgatgcaaa ctcaaaccct tttaattctt gcttttggag
    91141 agctttccct aaaactgata ataaagctcc tgactgagca gtcatcctag tatcatttat
    91201 ctcataagaa ttgaaattat cagctagttc tattaccact cctcttattc caccatcttt
    91261 aattaaaatg tttgaaccat ttccaattat taaatacgga atagattctt cttttaccaa
    91321 cttaagtaca ttttttaatt gttcttcagt tctaggtcta actaatatat ctgctggtcc
    91381 tcctacccta aatgaaatat gttttttcat aggttcatcg acttttatat cctctttact
    91441 taatatattt aataaattta tatatatatc ttgattattc attgtatttc ctcccaaatt
    91501 atactgaact ttagctgtca ttattattta aattacatta gtatatagta ttaactatat
    91561 tcaataatat atgattttgc ttatcatatg gattttatat tttaagcttc ttaattacaa
    91621 actatattca ataaatatat aataaagtaa aaaaaaaaaa ataacaacat ataaaagaat
    91681 ataaataatt taaaaaaagc atcaatatca ctgatatcaa tgctttaaaa ggcaatttaa
    91741 ttcgtattat ttatctaact atttttgaca tagcaaagat aataaatccc tccaactact
    91801 atggaacctc caacgatatt tccaagtgtt acaaatacca aattagttat aaattgaacc
    91861 atagttatat ttgctcctaa tgccattccc attggtataa aaaacatgtt tgcaacacta
    91921 tgttggaatc cacataatac aaatagcatt attactgtcc aacatgaagc caattttgac
    91981 attatatctt gagatgctgt agccatccat acagctaaaa cgactagaat attacaaagt
    92041 attgctttta aaaacattga tgctatagtt gaattaacct tagcttctgc cacagctata
    92101 gcttttgtag ctgcatctcc tgtcaatgta gaagaataaa acacaagtgc aactagcaaa
    92161 attgaaccta ctaaatttgc aaaataaacc agtccccagt ttcttaacat ttttcctaat
    92221 gttatttttt tgtccataag tgcaatagcc attaaggtgt ttccagtgaa taattctgct
    92281 cctgccacta ctacaagcat aagacctact ggaaagacca tagcacttaa aaagctagct
    92341 acccctgggt ctatcttgcc aaaagtttga ctaactatca tactccccaa tgccccaaaa
    92401 cctataaatg ctcctccaaa taaacctaat agaattgcgt tttgtgtcga aatatttgct
    92461 tttttaatgc ctgcacttat agttgcttgt gcagtttccc caggtgtcaa gaatccttta
    92521 ctcataaatc cttccccctt aaaaattata ctttcccttg tctttttatg gcaataatta
    92581 tataataaca atatgatata taataaattt tattaacata aaaaatatac tatatactta
    92641 tatatacttg tctcatataa ttatactatt tattatataa caactttgtt aatttcgaaa
    92701 taatttatat tgaatttgaa aaatttacct tttgattatt tattttactt tttaattatt
    92761 gaggtattat atataataga tatatgtttg tgttattata tataattact tattttaata
    92821 aatatttgaa ggagggaatt ttatgtttga tatatcattt ttcgaaatgt caatatatga
    92881 aatagcagtt actacaatat atataattaa tttcatggtt atactaaacc ttatctttag
    92941 agaaaaaaga aacataaata caactttaac atggcttctt atattagtat tgattcctgc
    93001 tcttggattc atactttata tagcttttgg cagaaatatt tcaaaaaaca atatgtttag
    93061 attgaaagaa aaggatgata agataatcaa aagtaatata ctagatactc aggttaaact
    93121 ccaatctaca tctgaaattg attcagatat acatcaacat aaggatatga tttatgcatt
    93181 ggctaattca aataatgctc attataccaa taataacgat gtgtggattt atgctgaatc
    93241 tagtcaattt tttaacagtc ttcttgaaga acttaaaaaa gctaaaaaat atataaacat
    93301 acaattttac attttcaaag atgacaaaat cggaactgaa ataatagaca ttcttataga
    93361 caaagctaaa gaaggtgttg aagtaagact tttatttgat gcagttggtg gtagaacact
    93421 aaaaaatagt acactttcca gacttaaaga aagtggtgtt aaagttggaa gcttcttccc
    93481 atcattcttg aaaattgtaa actttaactt aaactataga aatcaccgaa aaattgttgt
    93541 cattgatggt aaggtaggat ttgtaggtgg atataatgtt ggtgatgaat atttaggtag
    93601 aaatccaaaa tttggtctat ggagagatac acatactaag cttactggtg attgcgtaat
    93661 tgacctaaat atgagattca tccttgattg gagatataca actaaagaag acttagattt
    93721 agaaaaatac tttatagaag aagatacaaa ttctaatcat ccttctgaaa atattgggat
    93781 tcagatagta tcaagtggtc cagatatatc agaacttgat gagattaaat atggttacct
    93841 taaaatgatt cagaaagcta gaaagtatat atacatacag agtccttatt taatacttga
    93901 ctcaactttt atagatactt taaaaatagc ttgtttatct ggtgttgatg tgagagtgat
    93961 gattccttct aaacctgacc atccctttgt atactgggca tcatattcat atgctggaga
    94021 acttttaaag tttggagcta aaatctatac ttatggtcaa aatgcatttt tacatgctaa
    94081 gacaatagtt atagatgact ctatatgctc tataggaaca gctaatatgg atatcagaag
    94141 ttttgagctt aatttcgaag ttaatgcatt tatgtactct tcaaaaaaag cattggaaca
    94201 aagaattata tttgaaaatg atattttaaa ttctaaggaa ataacattag atatatataa
    94261 ttctaggtct acttatataa aaatcaagga atcaatttca agactattat cagcagtttt
    94321 ataaatcttt tattttataa aaattttaca ttttggttta ttttttaaag ttttttatat
    94381 gtattatttt ttttttattg aatttagctc atttttttta ttttttttaa ctattctgaa
    94441 ttattttata ttataataga ctagtatagt ttttattttt aataggtaac ttttttgcat
    94501 tgtttttata aataaagaaa ttgttgtata ttattctttc tttattgttt tggttttgtt
    94561 cacccacata atgttggggt caactcatgg ttaattattt tatgaaaaat aataacttta
    94621 aaaagaaaag ggggatttgt tatgtgcgat tttatttcac acaacaagca attatttgac
    94681 gaactagata tatttattga ctctcttgca acaaaggaag gtgcgttaat acaagttcta
    94741 catgaagccc aaggtatatt tggatatctt ccaaaagaag ttcaacttca tgttgctaga
    94801 aaacttggag tagctcctgc aaaggtatat ggggttgtta cattctattc ttattttact
    94861 acagaacctg taggtaagta taaaatcagt gtctgtctag gaactgtatg ttttgtaaaa
    94921 ggtgctgaca aaatcttaag tgcttttgaa aaacagcttg gcataaaagt tggagaaact
    94981 actagtgatt ttaaattttc tttagaaggt ttaagatgtt tgggggcatg tggtttagct
    95041 ccagttgtta ctgtaaatgg taaagtttat ggtaaagtga aacctgacca agtaagcgaa
    95101 atattagata cttatagaga attagaattg aattgttaag aggggtgaat aaataatgcg
    95161 taaagtaaat tcatttgatg aattaaaagt tttagctgat gagctgaaac ctaatcttag
    95221 cttaagaaaa aattattcta aggaaaatgt attaagaaga gaattacttg tttgttgtga
    95281 tactggatgt acatcttcaa acagtctaga aatagttagt gaattagaaa atgaaataaa
    95341 gaaatcagga atccaagata aagttagtgt tcgtttgaca ggttgttttg gtttctgtgc
    95401 tcaaggtcct attgtaaaag tttatcctga taacgttttc tacgtaaaag ttgagccatc
    95461 tgatgctgaa aagatagttc aaagccactt aattagaaat acagttgtcg aggaattatt
    95521 atatgaggaa gaatctttaa gtaaaaaagt tgaagaacaa gaagaaatgt ctttctacaa
    95581 aaaacagtta cgtatagctt taaaaaattg tggtcttata gacccagata gtatagaaga
    95641 atatattgcc aatgatggtt atttagctct aggcaaatgt ttaacttctc ttactcctca
    95701 agaagttatt gcagaggtaa aaacttctgg ccttcgtggt agaggtggtg caggtttccc
    95761 tactggctct aaatgggaag ctgcttcaaa aaatccagct ggtccaacag ataaaaagtt
    95821 tgttgtatgt aatgctgatg aaggtgaccc aggtgcattt atggatagat ctgtacttga
    95881 aggtgaccct catagtgtac tagaagctat ggcaatatgt ggatacgcta taggttctga
    95941 tacaggatac atatacataa gagcagaata tccaaaatct atagaaagat taaaagtagc
    96001 catagctcaa gctgaaaaat acggtttact tggcgaaaat atcttaggca ctggatttaa
    96061 ctttaaatta gaattaaaat atggtgcagg tgctttcgtt tgtggtgaag gtacagcgct
    96121 aatgcattca attgaaggta gacgtggtga acctagaatg aaaacttata gttcttctaa
    96181 gagtggtcta tggaaatctc ctacttgctt aaataacgtt gagacttttg ctaacatacc
    96241 tgcaattata cttaagggtg gagattggtt tgccaactta ggtactgaag attctagtgg
    96301 tactaaagtc tttgctcttg gtggaaaagt agaaaatgta ggacttgttg aagttccaat
    96361 gggtactact ttaagagata ttgtatttga aattggtggg ggaatccctg aaggtaagaa
    96421 atttaaggct gttcaaacag gtggaccatc tggtggatgt ataccaactg aacatttaga
    96481 cactcctata gactttggtt cattaagttc tatcggttca atgatgggct ctggtggtat
    96541 gcttgttctt gatgaatctg actgtatggt agatatagcc aagttcttcc ttgagtttac
    96601 tgttgaagaa tcttgtggta aatgtacacc ttgtcgtata ggtactacaa gattattaga
    96661 aatattaact aaaattacag aaggtaatgg tactctacaa gatttagatg acctagaaaa
    96721 ccttgctgaa actatacaaa ctgcttcatt atgtggtctt ggtaaagctg ctccaaaccc
    96781 tgttttaagt actcttcaat attttaaaga tgagtatata gctcatgttg tagataagaa
    96841 atgtcctgct ggtaaatgtc agaacttact ttcttacttt ataacagatg actgtaaggg
    96901 ttgtacaaaa tgttctagag tgtgtcctgc tggttgtata acaggttctg ttaaggaaca
    96961 acatacaata gatacttcta agtgtctaaa atgtggtgct tgtatagata attgtacatt
    97021 taacgctata atcaagaaat aacttatttg gaggaggaat aacaatgagt ttagttaatt
    97081 taactattaa tggcaaacac gtttcagcac ctagtggaac ttctatctta gatgctgcga
    97141 aattaataaa tataaaaata cacaaccttt gtcatttaca tatgaatgaa atagataagc
    97201 ttgacacttg tgcttcttgt cgtgtttgta tggttgagac agagagagga ttagttccag
    97261 cttgtggaac agttataaag gaaggtatga aagttcagac taatagtgct aaagcattaa
    97321 atgctcgtag aactattgtt gaattattgt tatcagacca tccacaagat tgttttgtct
    97381 gtgaaaaaaa tggagattgt gaattacaga ctatagctgc tgatttagga gtaagaaaaa
    97441 taagatatca aggttctaaa tcttttgcag gtaaagatac ttctactaaa tctttagtta
    97501 aagaccattc taagtgtata ttatgtagaa gatgtgagac tgtatgtaat gacatacaaa
    97561 cagtaggagc attatctgga gttaatcgtg gatttaatac tttagttagt acattcttta
    97621 actctgatat ggttgaaaca gagtgtacat tctgtggtca atgtatatct gtctgtccaa
    97681 ctggagcatt aacagaagta gataatgtac ctaaactttg ggatgtttta aataaaaaag
    97741 aaaagactat agtagtgcaa gttgctcctg ctgtaagagt tgctattggt gaagagtttg
    97801 gattagaacc agggtcaatc tctacaggga aaatggtagc tgctttaaaa gcacttggat
    97861 ttgaacatgt atttgataca aactttggtg cagattttac tataatggaa gaagctactg
    97921 aatttataga aagaatccaa aaaggtgaaa atcttcctat attaacaagt tgttgtcctg
    97981 catgggtaaa cttcttagag cacaattatc cagacaagtt aaacttagca tctagctgta
    98041 agtctcctca aggtatgttt ggttctatag ctaaaaacta ctatgcacct aaaatattag
    98101 gaatcaatcc tgaagaactt tatgttgtat ctgtaatgcc ttgtgtagct aaaaaatatg
    98161 aagcttcaag agaagaatta agtgaatctg gaatactaga tgttgacctt tctataacta
    98221 ctagagagtt agctaagatg ataaaagaag ctgcaatcga tttacctaat cttcaagacc
    98281 aagattttga taatcctcta ggaaaatcta caggtgctgc atctatattt ggagcaagtg
    98341 gtggagtttt agaagctgcc ctacgtactt catatgagaa gataactaat aagactttag
    98401 ataatgtaaa cttcactaat gttagaggtc ttaaaggaat tagggaagca agtatagatg
    98461 ttgatggaac tacagttaat gtgtgtattg taaatacact taaaaacgct agaaagatta
    98521 tggataaggt cagaagtgga gaatgtaaat accatatcat agaagttatg gcatgtcctg
    98581 gtggatgtgt tggaggtgct ggtcaacctt atcaccatgg taatactgaa atagttgata
    98641 gacgtgcaaa tgcgttatat gaaatagata gaaataaggc tattcgtaaa tctcatgaga
    98701 atcctgattt acaagctatt tataaagact tctttggaga accaaatagt gatgtagccc
    98761 ataaatacct tcatactcat tactttgata agagttgtgt ctatggagag tgtccacaag
    98821 aatgtgcttg tgaagaagct aagtagtcat aacaaaatat aaaatttatt cttaaaaaag
    98881 gattgtctta aaatactttt acgtaattta agacaatcct tattaatttc acaaattaaa
    98941 ttatatttct aaatagactt attctttaat taacctatct attaattaaa gaatacctgc
    99001 cattctcata agttgttttg catttgtagt tttacatctt ccatctttta tcttatagtc
    99061 aaaatgaatt ttatcgtcta catagtactc tgagaaatga tagtttacaa cttcaacatc
    99121 tccactacct gaaaggtcac atagctcaaa gtcatgtgtt gtcaccatac ttataaccca
    99181 gggttttgat aatttcttta ctgcctcact tgctccaata attctatcag cagagttagt
    99241 tcccttaaaa atttcatcta ctagaaccaa cattggcagt tcttttaaac tatattgaat
    99301 cattgatttt attctaagaa tctcagcata gaaagttgat attccttgac ttacatcatc
    99361 ttgtattctc atagaagtaa atatagccat acaggtcgca tcaaaactct tagcgcatac
    99421 tggagcacct gcatatgcca gcactaagtt tacaccgata cttcttaaaa atgttgtctt
    99481 tccagacata tttgaacctg tgataataca agtctgagaa tttaattgta tcgaatttgc
    99541 tatgacactt ttttctgcta ttaatgggtg gtatacctct tcaactttca atcttggagt
    99601 atcttcatat tttattactg gaaaacatgt attttccttt acatgagaaa taactgttaa
    99661 acttattaga gcttcaaatt ctccaataga ttcaaaccaa tctctaattt gatttccata
    99721 tatacctttc catcgctcca aagcttctgc acaatgatag ttccacatca aaacaccaca
    99781 ggcaattata tatagtatct gattatacct taggtttaca gcatttccta ttgaatttaa
    99841 ttgtttaaca cctcttgaaa ctccacttcc cttagaaagt ttatcttgta attctttcaa
    99901 atatgcactc tcaaacgtct ctttttctaa aacctcaaac attttttcat atacttgtat
    99961 acttctacta aatgaaaata atggagcaag agtttgcata agtcttggat atccaaaacc
   100021 actaaaccct aactggatta taaaaagtaa aaaaacaggt aaaacaggta aaaatcctaa
   100081 catacaaaat ataaaagata aaattgttgc agttggtaaa ccccaagtaa aaatatgcat
   100141 ccattttggt atatacacat tcttattttc tccatactct ataaacgatt ctatactact
   100201 atctgaatta tttttttgct ctttaccaat tatattactg agtgtttgaa tatgaataga
   100261 aaaatcatct tttgataaaa gttcttttat agctctctgt ctttctaaaa ttacattctc
   100321 atctggattt tcattccaca aatatttggc taaaaaattt ttcccataag atgtattagc
   100381 tacacagata tattgataca atgatgctct tccaaataag tctaaatctt ttgcttgcaa
   100441 gttttcatct tttaagtatt cttttccatc tattttaaat tccttccaac catctccaaa
   100501 tctcttaata tacttattta atacttcgct cttgctttta aaatatgttt cttcttcttt
   100561 tactttacta tgaataacta agagtgctat aaatattatt attgataaaa ctccaacaaa
   100621 aatacctact atatttttat tgtaaaatcc aatagcaagc cctgctatca ctatcaaaaa
   100681 agatattaat cttgctgtac ttatattatt tgacttttta cttaagagca attctttttc
   100741 agtactactt tctaaaagtt tactaaaata ttctattccc ataaaaaatt ccaactttct
   100801 tgttatataa tgaaactcaa atataaaatt aatctagtat tattataatc taacactgta
   100861 ctttaaatta tccttatata atatatctta ttaataaaca ttatatatat acaacttgat
   100921 tttaatttat aaggtgtagg atataatcct aatcaatatt taattaaatg atgtgtagtt
   100981 cactattatt cagtactact tagtatcgat taattttgat aattttttag taaattcttg
   101041 agctgcatcg tatcccattc ctctttgtct aaaattcatt gctgctactt ctaatatcat
   101101 agcagtattt cttccaggtt taacaggtac aactaatttc tctacattaa caccaagtat
   101161 ttcttcatat tctttatcca gtcctagtct atcataatac ttagtttcat cccaagcttc
   101221 taaatgaact actaaatcta tcattttaga atttttgatt gcccctactc catataaact
   101281 tctaacatct attattccta ttcctcttat ctcaagaaaa tgtcttatta gttcaggtga
   101341 ctgacccaca agcatacttt catctaattt tcttatttct acagcatcat ctgcaactaa
   101401 tctattaccc ctttgaatca gttctaatgc tgtttccgac tttcctatac tactttcacc
   101461 ttttatcagt acacctatac cataaatatc tactagcacc ccgtgaattg ttgtgtgtgg
   101521 tgctaactta ttatccaaat agtttgacag tctatttata agtctagtgg tatttctatt
   101581 tgtgctcaaa agtattcttt tatatttttt agccttttca attacatctg gcttgatttc
   101641 caagtctcta gaaattatta acgctggtat ttcatatgag aaaaatctat ctagtacttc
   101701 ttctcgaata tgactatcca ttaatccaaa aaaattatat tctgtctttc caactatttg
   101761 tattctttca tatgcaaaat aatcaaaata tcctgcaaac tgtaatcctg gtctatttat
   101821 atcttgagag tagacataat aatctacatc atcaggcatg tatactactt ttaacttcaa
   101881 ctcttttatt atctctctta ttgatacttt attgctagtt tccattaatt ttcttccttt
   101941 ctaaaaaaat tataaacatt atctgcaatg cttttattca ttccatctac ttctaaaagt
   102001 tcttccatag tagctttttt tatagcatct acatctttaa agtgatttaa taatgatttc
   102061 tttctttttt cacctattcc ttgtatatca tctaagatag attttgtcaa agctttattt
   102121 cttagacttc tatgatatgt tattgcataa ttatgaactt cttcttgtat actagcaata
   102181 aatctatata aattagttgt tttatctagt tctatttctt tttctttgca tatcaatcct
   102241 ttagttctat gcttatcatc tttgtacatt ccccaaagag gtatatctac atcattgagt
   102301 tctagtactt tttttactgc actaacttgt ccttttccac catccaacaa tatcaagtca
   102361 ggtaaatttc catgttttaa tcttctatct acaatttcag ccatagaatc ataatcatta
   102421 ggtccaataa ctgtctttat tttatatctc ctatattcct tcttatcttt tttagcattc
   102481 gtatacacta ccatagaacc aatcgaatct acaccttgta tatttgatat atcataagcc
   102541 tctattctta ttggcaactt ttctagattt aatatttgct ttaattcttc caatgctcca
   102601 atactttttt catattttct tttattcata tcagaaaatt tttcaagata ttctacagca
   102661 tttttcctaa ccatttcaac taagcttttc ttctctccct tttgaggaac tcttattgtt
   102721 actttttgcc cctttttaga tgacagccat tcttctaata tagaactatc ttctatctca
   102781 tcttctataa ttaattcttt aggtatatac tcttgttcat tataaaattg ttttacaaat
   102841 gaacttaata tagaagctct tggactatcc attacccctt ctaatataaa atgttcccta
   102901 cctacaatct taccatttct tataaaaaat acctggacac aagcttcatt atgagctctt
   102961 gccattgcaa ccacatcttg gtttaagtca cttacagtag catctatttt ttgtttctgt
   103021 atcatctctt caaggctctt tatcttatcc ctatatacag cagcctcttc aaatctaaag
   103081 ttcatagaac tctcattcat tttttccttt aaaagttcca tcaatttttc ttctttacca
   103141 gataaacaca ttataatctc ttctatcatt tttccatact cttctttaga aacatttcct
   103201 gtacaaggtc ctaaacattt atttatgtgt agatttaaac aaggtcttgt cttattcttt
   103261 attgctttat ctatatctat tttacagctt cttattggat acgtactact tataagctcc
   103321 aaggtatcat tcacagcagt tatattggta tagggcccaa aatactttgc cttatcttta
   103381 agaactcttc taacttttaa gattcttgga taatcttcat tcgtagttac ttttatatat
   103441 ggataagttt tatcatctct aagcactaca ttatactttg gtctgtatct ttttattaaa
   103501 ttacattcaa gtattaatgc ctctaactct gaatccgtta taatatactc aaacttatat
   103561 atattcttaa ccatagattt tactttagat gtatggtttt ttgaagattg aaaatactgc
   103621 cttaccctat tttttagaga tatggctttt cccacatata ttatatggtc gtatttgtct
   103681 ttcattaaat atactccggg ctcagaaggt aattttttta aatgctcttg tatatcaaac
   103741 atctcgccct ccaaaacatt aaattttata ctaaaattat accctaaaat atgaatttta
   103801 aaaagttata caatttccag tgctttaaac aagttaaagc ccatattccc ttctataatt
   103861 gatttgaaaa caattttaac catgaagagt aatatggact ttactttgta ttactattta
   103921 caacttatat ttgactaatt tacttataac aaaacagttt atcgtatatc tgctctaaaa
   103981 tttttcacaa tttatataac ttaagaaaaa tatttcttta agaattgacc tgtataagaa
   104041 ccatcaactt tagatacttc ttttggtgtt ccagttgcaa ctatagttcc acccttatct
   104101 ccgccttctg gtcctaagtc tattacataa tcacaagtct ttataacatc taaattatgt
   104161 tctatgacta taattgtatt tcctgtatct gctagtcttt gtaatacttg gattagcttg
   104221 tctacatctg ccatatgaag tccagtagta ggttcatcta atatatacaa agtctttcct
   104281 gttggtcttt tactaagttc agcagctaat tttatacgtt gtgcttctcc tcctgataat
   104341 tgagttgaag gctgtcctaa tttaatatat gaaagtccta catccattaa agtttctaat
   104401 tttcttttta tatttggtat attttcgaaa aactcaacag cttcttccac attcatatct
   104461 aatatatcag atatagtttt atctttgtat tttacttgca atgtttctct attgtatctt
   104521 tcacctttac aaatttcaca aggaacatat acatctggta agaaatgcat ttctattttt
   104581 attattccat cacccttaca agcttcacat ctaccacctt ttacattaaa gctaaatcta
   104641 ccttttttat aacctcttgc tttagcttca ttagtagatg caaaaatatc tcttataaaa
   104701 tcaaatacac ctgtataagt agcaggattt gaacgaggtg ttcttccaat aggactttgg
   104761 tctatattta taactttatc tatactttca attcctttta tctccttatg cttaccagct
   104821 ctttgcttaa gtctattcac tttacttgca acacctttgt aaagtatatc gtttattaat
   104881 gtactttttc cggaacctga aacacctgtt atacatgtaa acttacctaa tgggaacttt
   104941 acatcaatat ttttcagatt attttctgat gctttaacta tttctataaa acttccattt
   105001 ccttctctag tagtctcagg aagcaatatt tgttttttac cacttaaata ttgacccgtt
   105061 attgagttct cattttcaat tatttcatct aaagtaccct gtgcaactat ttcaccacca
   105121 tgtatacctg cacctggacc aatgtctata acataatcag cttctctcat tgtgtcttca
   105181 tcatgctcta caacgattaa ggtatttcct aaatctgtta gatgtctaag agtagttata
   105241 agcctatcat tatctctttg gtgaagccct atacttggct catcaagtac atataaaact
   105301 ccaaccaatg cagaacctat ttgagtagct aatcttatac gttgcgcttc tcctcctgat
   105361 aaagttccag cttttcttga taaatttaaa taatcaagac ctacatctct taagaacata
   105421 gctcttcctt ttatctcttt tataatctca tgagctataa atctctgttt ttctgtaaga
   105481 tttatatttt ccataaagtc aatcaattca tttacagata agtttgtaac ttccattata
   105541 ttttttccat caactaaaac agataaaact tcctttttaa gtctcatccc tttacacttt
   105601 ggacatggtc tctctgccat gtattcttca atcttatctc tcatgtaatc tgaattagtt
   105661 tctctatatc ttctctctaa gtttactatt acaccttcaa agtatgattt ataatttcta
   105721 gttcctccaa attttgactc ataagtaaac tctacaatta tattatcttt accataaagt
   105781 aattcctcca caaaatcatc tggtaaatct ttaaacggtg ttgtcaaaga tacattaaaa
   105841 tgctctgcta aactttttat cattttgctg taataagtgt catcattaac acctgttgaa
   105901 ccccatgctg ccactgcacc ttgttttatt gataaatctt tgtttggtac tactaattct
   105961 gggtcaactt ctttactttc cccaagacca ttacaaacat cacaagcacc aaagggagca
   106021 ttaaatgaaa acattcttgg agataattct tctatgccaa ttccatgttc tgggcatgca
   106081 aatttagttg aaaaaagaat ttcttctcca tctattattt gggctattac aagaccatca
   106141 gatagcttaa ctgcagtttc aattgaatct gctagtcttg attctattcc atctttaatt
   106201 actattctgt ccactacaac ttctatatta tgtttttgat ttttatttaa gattatatca
   106261 tcactaactt catagttttc accattaact ctaactctta caaatccttc ctttttgata
   106321 ttatcaaaga cttttttatg tgtacctttt tgtcctctaa caattggtga aagaatttgt
   106381 aatttcgttc tatctggaaa atctagcatt ttatcaacta tttcttgaat agtcatctga
   106441 cttatttttt caccacatgt agggcaatac acatctccta ctcttgcaaa taatagtctc
   106501 aaataatcat atatttctgt tactgttcca accgtagaac gtgggttttt tgaggtagtc
   106561 ttctggtcaa ttgagatagc tggtgataaa ccctctatat attctacatt tggcttttcc
   106621 atctgaccta aaaattgtct tgcataagca gatagacttt ctacatatct tctctgtcct
   106681 tctgcatata ttgtatcaaa tgccaaagaa gacttcccag accctgacaa acctgtaaaa
   106741 acaataaatt tatctcttgg taattctaaa tctatatttt ttaaattatg ttcttttgct
   106801 cctcttatta taattttatc ttccataatg ttgtttttac ctttctattt ttccaatttt
   106861 tcttctaatt gtttcacttt atctctaagt tctgctgctc tttcaaattg taagttttga
   106921 gcagcttcca tcatctctga ttttaattta tctatattag ctcttatttc gtctttatca
   106981 tctgtatcag atattccata tacaacttct tcctctgcaa ccttagtagc ttctatacta
   107041 tctcttatat ttttctgtat agttttagga atgatattgt gctcttcatt atataaattt
   107101 tgtatatctc ttcttctctt tgtttcatca atagcatttt gcattgagtc agttatcctg
   107161 tctgcataca taattactct tccattttca tttctagctg cacgtccaat agtctgtatt
   107221 aaagctgttt cggaacgtaa gaaaccttct ttgtctgcat ctaaaattgc tataagtgaa
   107281 acttctggta tatccaatcc ttctctaagt aagtttattc ctacaaggac atcaaacttc
   107341 cctaatctta aatctcttat tatttctgtt ctttctaatg taactatatc tgagtgtaaa
   107401 tatttaactt ttatccctat ttctttaaga tagttagtca agtcctcact cattttttta
   107461 gttaaagtgg ttataagcac tctttcattt ttttctatag ttttagttat ttctcctacc
   107521 aaatcatcta tttgattatt tataggtctt acttctacaa ttgggtctaa aaggccagtt
   107581 ggtcttatta tctgttctgc tattgtctct gagtgttgaa tttcataagg tcctggtgta
   107641 gcacttacaa acaacatttg atttatattt ccttcaaatt cttgaaaatt taatggtcta
   107701 ttgtcaagtg cagaaggtaa tctaaaacca ttctctataa gtgatgtttt tctagacctg
   107761 tctcctgcat acatacctct tacttgtggt atagtgacat gtgcctcatc tataattatc
   107821 aaataatcat ctgggaagaa atccattaaa gtatatggtc tttctccttc tgaccttcct
   107881 gtaatatgtc tagaatagtt ctctatcccc tgacaaaatc ctatttcctt taacatttct
   107941 atatcatact tagttctttg ttcaattctt tgtgcttcta atagcctatc attttccttg
   108001 aaaaatttaa tttgttcttg aagctcgttt tctatttcta caattgcctt ttcaattctt
   108061 tctggcgttg ttacatagtg agatgctggg aatataacaa catgatttct agtaccaaca
   108121 atcttccctg ttacataatc aatttctgtt attctatcta cctcatcacc aaaaaattct
   108181 attcttattg ctttttcatc attactagct gggaatattt ctagtatatc tcctctaact
   108241 ctaaaggtac ctcgtgtaaa gtttatgtca tttctttcgt attgtatctc tattaacctt
   108301 tttattacat catctctgtc tctttgcata cctggtctta tagataacat aagttcttta
   108361 tagtcttttg ggtcaccaag tccatatata caagatacag atgatattat tatagtatct
   108421 cttctctcta aaatagatgc tgtagcagaa tgtcgaagtt tatctatttc atcatttatg
   108481 cttgcatctt tttctatata agtgtcactg tgagctacat atgcttctgg ttgataataa
   108541 tcatagtaac ttacaaagta ttcaactgca ttgtctggga aaaattcttt aaactcactg
   108601 taaagttgtg ctgctagagt tttattatga gccattatta gggtaggttt cttaacttgt
   108661 tgaatgatat ttgccattgt gaatgttttt cctgaacccg ttacacctaa taatgtcgaa
   108721 aatttctcat ttctatttat agaatccact attgatttaa tagcttctgg ttggtcacct
   108781 gtaggtttga agtctgattt tattttaaaa tccatagtat cactcctttt ttcgaacatt
   108841 agttcctgac atgtattatt atatcatacc tttataaaat tgtttaagtt attttaaata
   108901 ttttacccat ttaaatttta cttaaatcta aaacataaaa aaagacttct atctttgcaa
   108961 tagaagtcta taattcatgg aaaataaata ctttattcaa cttacataat aaaatcaaat
   109021 gcttcttttt caactccatc taattttaaa ttaaacattt ttaatatagt tgctgcatgt
   109081 gctctcaggt ctccttcttc tataaccaca ccacctttaa tatttggtcc aaaagctata
   109141 aatggaggtc tattaccttt agtaggtaaa tgaccatgtg tcgcaacagc aaacttgtaa
   109201 tcttttatat ctgaatcttt tataatactt ccttcgaaat catttccaaa tgaaattcct
   109261 tcaagacctt caatcactat ttcaaaatca ccttcaagac caaggttaga tgcttcctct
   109321 ttggtaaaaa tattctctat gaataattct tctttaaatt cttcaagcag ttctcttaat
   109381 tctgttaacc tatctaagtt atttactatt atttgagctg atattccaga agaatttaca
   109441 taggcatcaa aatccttaac ttctccattt tcaactttta taaatccatt tgatttaagc
   109501 aagacatttg gatttataac tttatcaact ctaagatgac catggtcccc aagtattata
   109561 aaatttgtat ctttgtatgt acctgcatcc tttgtagcct gaataatatc tcctagccat
   109621 ttatcattca tttttaatgc tttatctact tcgtcattaa ataatccata attatgtcgt
   109681 gtatggtcca atgtagctaa atgtattagc attaaatctg gtttatattc ctttattata
   109741 tctactgaac agtttactcc aaataaatcc atgttgggtt ctaatttcca atcgatataa
   109801 tgacaatgtc tattgtaaat accgtccatt ataaccttac tggaacttcg ttcaaaagtt
   109861 tctcttgggt catcttctct actaggagcc catatttctg caatattata atctatattt
   109921 ggatttgctc ccattacagg ccataataca ctagaggtag ttagattatt ttcttttgct
   109981 acatctataa tagtttttgc ttttatgtcc tttgagtacc agtaccagtc tttattttct
   110041 ttatttgggt caaatttttc attatgatat ataccatgtt ttttaggata tactcctgta
   110101 accatactag tatgacacgg atatgtcaga gtgggataaa cacaatttat attttttact
   110161 atggagcaat tttctagtat agatttaaag tttggtagat tttttacaaa ttccaagtct
   110221 ttttcaaata aagaatctac tgataatact ataacctttg tcatttacat tacctcttca
   110281 tttatatatt attgaatact tttaatcaac ttacaagtct atataattat ttatttgttt
   110341 tatctattac tgcttgcatt gcagaagttc ctttgcttac tacatctttt ggatttgcat
   110401 ttaaatcagt aagccccttt ttaatctcat ccattagctt atcagttgct tccttgtatc
   110461 catttaacat tggaagtgca acagcatatt gtaattggtc agttgcaacc ttatattgag
   110521 gtttttcttt atataatgtt tgtaactttt ctgagtttgt tgcatcttca gttgttggta
   110581 agtatcctgt tgatgaacta aactgaacga ttttatctgt ttgtgtcatc cattctataa
   110641 attctgcact tgcttctttt tctttatctg ttccaccttc aagcataact agattagctc
   110701 cacctgtagg agttgcgtat ttttgatttt ttggtaagaa tgctgttgat atttcaaact
   110761 taccttctgt ttgttgcata agtcctgcta aatctgctgt tgatgtaaat atcataccta
   110821 ctttaccatt tacaaaatct tgttttgcta cgtcccaggc attataatct tctccaggag
   110881 gcattttcat tattccagct ttcatcatat cttgccaaaa cttaactggt gcttgtcctg
   110941 cctcattatt aaatgctact tttttaccat tagttatttc tcctccactt tgcattacca
   111001 tagcttcata gaaccaaata tctattggcg tttcaaaacc ataagtatct tctgatttat
   111061 ttgtcatttt actagcataa tccttaagct cttcccatga ttttggacct gaagggtcaa
   111121 gacctgcttt agttgccata tctttattta tgtataatat tggtgtactt ctattaaatg
   111181 gcataccaac aaacttatcc tcataatatg aatttgttaa aagaccagaa aagaatcttt
   111241 cttgatatgt tttatcaaaa tatttactca tatctactaa agcacctgct gatgcgaatg
   111301 tacctgtttg agttatttct aataatgtta catctggttg gtctttagat gttaaggctg
   111361 cctgtagttt tgttgcattt tcatagtaat ctttctgttt taacatattt acttgtacat
   111421 ccttatgttc actattaaat tggtcaacca ttttttgagc agtttctcca ttagttccac
   111481 ctaaaggagc ccagaaatct atcttcgtaa tattgctatc agtcttttct cctttagatg
   111541 catttgcatc attagaattt gaacacccaa ctaaagaacc taataataat gttattgcta
   111601 atcctgttgc taattttctt ttaagcttca ttttcatcct ccaaatttag tctttaattt
   111661 tttattttat tcctgaatac ataaaagctt cttttacttt tttattcgca aatatataaa
   111721 caagaattat tggtaaaatt agaattatat ttcctgccat tattacattc catgcagtaa
   111781 ttccttctga agatttaagg agcgcaactc ctattggtaa agttcttatt gcatctgtat
   111841 ttgtcattac taagggccag aaataattat tccaatggta tataaaatta aataatataa
   111901 atgttattac tgctggtttt gccataggaa ccattattct aaacattatt tttaagtcag
   111961 aagcattatc tagtttagct gcttcaataa tttcatctga aatctgcata aaattctgtc
   112021 taagcagaaa tatcccaaat gaagatgtca taaatggaat tataagtgga acataagtat
   112081 ttataaatcc aaacttactc atcatcatat agactggtag aaaagttact tgtggtggaa
   112141 tcataagtcc tacaagcaaa agcccaaata gcattttttc acctttaaat ttaatcttag
   112201 aaaatgcata tgctgctgga accataacta aaaattgtac aattaaaaca cttcctgtta
   112261 caaatacact gtttagcaaa tatctaaaaa atggacctga atgccatgct gtactataat
   112321 tttctaacac tatatcattt ggtataatag tgggcggtaa ttgcatcatt tcttgtggat
   112381 ttttaaagga tgtagatagc atccatataa aagggaatat aaatattgca gataaaagta
   112441 atagaattaa tatttctatt gattttgatg ctattttttt tatatcaact ttgtcttttt
   112501 tgataggttg tataatatcc attgtctcct ccttttggat aaaccttata atatctactt
   112561 tttctttatt gataatgaac tttctttgat aagagtctaa agttagcata tgtagcaatc
   112621 ataactatag ctaacaaaaa catactcgct gcactcgctt gtcctatgtc atagtatata
   112681 aatccagact catatatata ataagataac atgttagttg aacccactgg cccaccttgt
   112741 gtcattatac ttatctcatc aaatacttga aaagatgcag ttgttgttgt tatcataaga
   112801 aaaaatattg ttggtgataa tagtggcaat gtcactttaa agaaattcgt tattttgttt
   112861 gcattatcta atttagatgc ttcatatata tagtttggta tggatttaag acctgataac
   112921 actattaaga tattatatcc aagagtcttc catattccta ttagaattag tgacattaaa
   112981 gctgaacttt cacttgaaag ccactttgat gttggtaaat gtaatgtcga tagtatccag
   113041 tttaaaaagc catattgtgg ctccataatc caaagccaca atacagctac agatactagt
   113101 gaaattacat gtggtgtaaa gattatactt tgcgttaaat tgtgtattat agaattttta
   113161 tttagccaaa cagcaagtac tatggctagt gatatagata tagtcaccat aaaaaaagta
   113221 taaattgcag tgttcgttat agtttgtata aactctggat tctttaaaag ttctgtataa
   113281 ttgtttaagc ctacattttc aaaggttgaa ctaagaagac taccagattt gaagcttaga
   113341 gatatcgtct taattattgg atagactata aacaataaag ttcctataat agcaggtgtt
   113401 atatataaat atgctttatt aaattgcttt ttcataaata tctcctttaa ttttagaata
   113461 catactttta catactttta catcttctat tctttctcca tttttatcaa aataatataa
   113521 atctttttct aatacactta ttcttaaagt tcttccaata tcaaatatat cattttccgt
   113581 tttgactctt atctctctat taagaacaga taaacaatat atagtttcat ttcccaacac
   113641 ttctttagtt acaacttttc caaatagact aaatacatca tcatttttcc catctatgtt
   113701 tatactctct agtgttgctt tttctggtct gaatccaaat ttaatatcat tttttatatc
   113761 tagtatgttc atacaaggac tccctataaa ttgagctaca aataaatttt taggattttg
   113821 atatatcttc tttggagaac ctatttgcat tatctttcct ttgttcatta taactatctt
   113881 atctgccatc gacattgcct caacctggtc atgagttaca taaacaaatg tagactttag
   113941 tttttgatgt aattgtatta attctgttct catttgattt cttaatttag catctaaatt
   114001 tgacaatggt tcatccatta aaaatacctt tggattttta accatagctc tagcaagtgc
   114061 cactctttgt ctttgacctc cagataagtt gcctggtttc acatttaaat attctctcaa
   114121 tcctactaca tcaataactt ctgttataag tttttctctt ttttcttttt ctactttttt
   114181 gtttttaaga ccaaattcta tgttttctct aacagtcata tgtggatata atgcataatt
   114241 ttgaaatacc atagctatat cccttttact agcatccgtt tttgtaacat cattttcttc
   114301 aatcttcaac ctacctgaag ttatatcttc aagacctgca atcattctta acgtagtaga
   114361 tttaccacat ccacttgggc ctaccaatac tgtaaaagaa ccatcttcta tagtaagatt
   114421 taaattttct ataactgtat tttttttatt ataagatttt gttacatttt ctagtcttat
   114481 atctgccatt tttatcctcc caaaatattt aatttaattc tacgatttac ttatagatta
   114541 ataatactct taatttgtaa aggatatatt aagacaaagt gaatatatag taaacttatt
   114601 aaaataaagg ttaaattata aacatttttt gttaaatata ctgaagttaa gatgatatac
   114661 agcttatgtt agctataatt ttctatattt ttcatattca tggtttgcta tcacaatgtg
   114721 attttaattt atgaagagtc atataaaact atttattttt tatataattt ggtttgaaaa
   114781 taaaaaagac ctctatgggg gatagaggtc tttaagtggg ggagattgag taatttattt
   114841 ttgctatatt aagttttaca attatattat gtcccaaatt tacaaggttt aaacataaaa
   114901 aataaaactt ttttaatttt tataaattta cccaaaaaaa a
//
LOCUS       DAMKNB010000002       114753 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.002, whole genome shotgun sequence.
ACCESSION   DAMKNB010000002 DAMKNB010000000
VERSION     DAMKNB010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 114753)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 114753)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..114753
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.002"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            complement(118..1719)
                     /locus_tag="PC494_000099"
     CDS             complement(118..1719)
                     /locus_tag="PC494_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HDF3910633.1"
                     /translation="MIYDLILKNGFIIDGTGNPGFYGDIAIKDNLIAKIDSKINSNTN
                     KEIDCCGKVITPGFIDPHVHEEIVAILDGKFEKFLKQGVTTTINGNCGHSITPYSSEN
                     VYEYMYKNGLLLEEEKKYLIDKNKCWNNFTEYCDLISKSGISVNMGFLLGHGTIRWSV
                     MGGSKDRPPTEKEKNEITDIINDGMKSGAFGISTGLAYIPSKYADIDELVDIARQIKE
                     YDGIYTSHIRDYIGRYNAVKEAIEVGQKSGARVQVSHLSPVEIEAFDEILKARYNGVE
                     IMVDTVPRSSGHCMKKKRVIQFIMAISSSLFELGIDGVMDALRNEEGRTLILKEAFIL
                     GDRGSIILLNTKDINMEKKSIREIATQKGIDEDKLLLDLLLDGDEELIFCLGGMYRAD
                     FPDKLHDDKIIDNPFVMVGSDCLFSVGGDMSWFELQRRGAFPIFFNMYRKSGVRLEEI
                     VRRVTSLPARQFKIKNRGILKEGLIADIAVIDMDNYSYPRSEDIDFSKPQLLANGVEY
                     VIVNGKIALENGEITENKCGEVLKR"
     gene            complement(1830..2507)
                     /locus_tag="PC494_000100"
     CDS             complement(1830..2507)
                     /locus_tag="PC494_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3910634.1"
                     /translation="MSKVKSIYNEEYLPFMIRYGRLTLSLGIIAALVPGIILSFGFGI
                     MPPISALLASTMAIVSMSAPNYIIEPVSYSPILGIPGTYMSFLSGNISNMRLPCSIAA
                     QKAAEVESGTEEGSIISTIGIAVSILVNISILTIGVILGGSVLSKIPAEVVEKLNLIL
                     PALFGSVFGQVFLQDKKLGLVAIVISVLTIILSKQGIIPQSLVVLICVFGTILIARAM
                     YKDKLSD"
     gene            complement(2524..3219)
                     /locus_tag="PC494_000101"
     CDS             complement(2524..3219)
                     /locus_tag="PC494_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5058 family protein"
                     /protein_id="HDF3910635.1"
                     /translation="MDYLKLANHPLLWIASTVAVSIVVVQSLIFAIKSCKVGKTMGIT
                     DKQIKSAVKSSAISAIGPSMTIFAGMVSLIVTMGGPIAWMRLSFIGSVIFESMSAGFG
                     TDALGITLGSPEMTKLAFTNAVWTMILGSLGWIIFTLLFGHKLDKITNVISSGKKSFI
                     PIISLGAMLGSFAYLNADRVLRFDNGTIACISGMAIMVILCMLEKKKNIKWLREWGLT
                     ISMFSGMIIASVI"
     gene            complement(3271..4470)
                     /locus_tag="PC494_000102"
     CDS             complement(3271..4470)
                     /locus_tag="PC494_000102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane dipeptidase"
                     /protein_id="HDF3910636.1"
                     /translation="MKSAYKGYEAYSYLEKGKDISSIEMCKGDKRVKEYLIELDDIQE
                     AKVKSIVDEKIFISLHEHPVLFPEHLERDIFEYNREGKQRCAYEALSRGYYDAIFDNL
                     MDGVCTITSNSGWKWDDILIDLGMRLCDLAHQDFVIKCEKVEDIYRAKSEGKVALIPT
                     LEGAAPIENELDRIDILYGFGIRLMGITYSESNALGSGLKEEKDGGLTNFGKKAVERM
                     NKIGMAIDCSHVGVQTTLDVIEYSKDPIILSHVGARNLWNTKRLTPDEVLIACAKKGG
                     VIGVEAAPHTTITEKNKEHSIESFMEHFEYIKNLVGIDHVAFGPDTVYGDHVKLHSVL
                     AAKFDIKKITGTKEHPKVEYVKGLENPTETSKNIVRYLVKHGYSDEEIEKVLGGNILR
                     VLKQVWK"
     gene            complement(4731..6776)
                     /locus_tag="PC494_000103"
     CDS             complement(4731..6776)
                     /locus_tag="PC494_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDF3910637.1"
                     /translation="MKKHNILFVSTDDKINIDISKQLENIFGEFCNIDNLVYVNRINI
                     ELSSYELVVCSDNDIKEYIHNNIDKNIPIVIVHRTINIENINQIISIENDSDVMVIDA
                     YKESADETAKIIRKLGLIHINLIPYYPGCDKSKCEIGIITGSRNSIPQNIKQIIDIGD
                     KVIDINTVIEIFTKLNISIDKLHIIKEKYNEDTVSGYRYYTTMNKTMKSFLEIIDEGI
                     ASVDKLGKFIYCNKVFSNLVGIDQNEIISNNFMDLFSDKVVKKIFFQEDEVNDEVVNL
                     NNKKLIINKVNVYENNERIKSIISIKNISAIQVLEDKIQNKLQSKGFVSKYTFESVVG
                     ESKIIKEKINIARKIATTDFSVLILGENGTGKEIFAQAIHNESLRKNKPFVAVNLSSL
                     SDTLIESELFGYDEGSFTGAIKGGKMGIFERAHTGTIFLDEIGDISLDVQQRLLRVLQ
                     EKEVMRMGGSKIIPIDVRIIAATNKDLKKKIKEGSFREDLYYRINVLHIEIPRLRERK
                     EDIPLISKYFLDEINSNKCFTEESMQALTLYEWPGNVRELKNLIYYIDTIVEEDRVDY
                     EHLPEQFRFEKNNTLVNENFDSIILDFKQSNFFEESICILTSIETWNNKNILLGRNKL
                     QEILKEKDIVLSVDQIRKRIDKLKSHGLLLSGVKKQGSFITDEGKNFISYVKIKGVI"
     gene            complement(7187..7996)
                     /locus_tag="PC494_000104"
     CDS             complement(7187..7996)
                     /locus_tag="PC494_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDF3910638.1"
                     /translation="MYYVYVNDINIAVYDLNPSAKKTVLFIHGWPLGHKIFEYQTNIL
                     PKLGYRTVSIDLRGFGKSDATSGGYTYSQLADDIYKVVHAIGLKDFTLVGFSMGGAIV
                     LRYMSLFNGYGVSKLVLAAAAAPSFVQRPPEFPYGMTREDVNKLIAQACTDRPEMVTD
                     FGEKVFASNPPESFRRWFNDIGFSASGIGTIGTAVSLRDEELFNDLKCVRVPTGIFHG
                     KLDEICPYEFAVFMNEKIEDSILYTFEYSGHAIFYDELKLFNQEFLQFLEE"
     gene            complement(8080..8613)
                     /locus_tag="PC494_000105"
     CDS             complement(8080..8613)
                     /locus_tag="PC494_000105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese catalase family protein"
                     /protein_id="HDF3910639.1"
                     /translation="MSDAHYDMHKRNGYSSDEPYPEIKVLGPNKYYAELLMDDYAGVS
                     SEFTSVNQYLYHNFDLDETHRELSEMWINISITEMLHMEILAKTIRLLGGNPVYRGST
                     SSCGAYWNGGFVCYGNSICNRLKLDLHLEHVAINNYYKDISLIEDPYIKAILNRIILD
                     EKLHVSLFEKAIEKYCK"
     gene            complement(8763..10112)
                     /locus_tag="PC494_000106"
     CDS             complement(8763..10112)
                     /locus_tag="PC494_000106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TldD/PmbA family protein"
                     /protein_id="HDF3910640.1"
                     /translation="MELKNFKDILFKKALSEGFEECEIYYYTGENLSINIYEGEVEKY
                     NLDKSFGLSFRGKVNGKIGYSYTEILDDKAVDMLIKNVKDGVNTIENEDVQFIYEGDK
                     HYNDVKTYSKELENLEADKLIDLALEMERETKAYSDKVVNLSKCTISYSVSSNGISNT
                     KGLNLSNKTNMLIGFVVPIIEDNGQKYDGIGYNIANSIEEIKPCEIAKLGVDNALSKV
                     GGKSIPSGKYKTILLNEAMVSLLSTFSGIFNADSAQKGLSLLKNREGDMIASPIVTIV
                     DDPLLENGMASTPFDDEGVATFKKEVVLNGKLITLLHNLKTANKAGVKTTGNGIKSSY
                     SSPISIYPTNFYIEKGDKSLDEIIKDIDEGLMVTSFAGLHSGANSVTGDFSLAAKGFY
                     IKEGKKVFPVEQITVAGNYFDLLKDIEAIGEDLEFPMSSIGSPSVVIKELSVAGKDE"
     gene            complement(10124..11506)
                     /locus_tag="PC494_000107"
     CDS             complement(10124..11506)
                     /locus_tag="PC494_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011967718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TldD/PmbA family protein"
                     /protein_id="HDF3910641.1"
                     /translation="MLSKNIASKVLEKCLITGGDFAEIFEEDTINNSISLIDNKVENA
                     IGGRNYGIGIRIFKGLKSIYAYTSDNSLNSLLDVAYKAAVALGKLEDGKSVILNDSIK
                     INNIHNIKIYPNSIGNKDKVSVMKVAYKSAKEFSNDISQVSVSYLDKDQKILIANTEG
                     IYVEDRRIRTRLGISSIASKGNENQTGFEGPGGCKGFEIFEEIDPEYYAKESARVAHT
                     MLHAKNCPAGNMMVAIDNGFGGVIFHEACGHSLEATSVAKGNSVFADKLGQQIASTKI
                     TAIDDGTIPNYWGSMNIDDEGNPTQKNILIENGILKSYMIDKLNGRRMGMNPTGSSRR
                     QNYKFAPTSRMTNTYIAAGEDKPEDIIKSIPDGLYAKKMGGGSVNPVTGEFNFAVSEG
                     YLIKNGEIQEPVRGASLIGKGSDILMNIDMIGNNVKQAQGMCGSSSGSIPTNVGQPMI
                     RVKEITVGGR"
     gene            11750..12964
                     /locus_tag="PC494_000108"
     CDS             11750..12964
                     /locus_tag="PC494_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HDF3910642.1"
                     /translation="MNQEYVKGNPIFTNINKVPRQFPYLTDDIDTDVIIVGGGVTGCI
                     CAYYLAKNNIKSVILEKGRIAHGSTSVTTSLLQYELDDNLIDLTEVMTLKDALKAYNL
                     CTSALEELDTFIELYGNKCDYAKRDTLLYTANKLEVKAIKEEYNLRKENGFDVEYIDE
                     STNPFSFDLKSGLIAKNGGRELDPYKYSHHLIDVSLKNGLQVYENTEVKKVDLSNDKV
                     TAEVSYGYKVHGKKLIVATGYNTSLFTKRNFATKSNTFNIATKPLKNIASWKNNILIR
                     DNCDPYNYLRTTKDNRLIIGGEDVSFDDIENETLANEKYDILEQRLKSMFKDIKDIEV
                     EYKYCGCFASTLDNLGFIGPDNKNNNLWYCLGYGANGILFAILGGIMLSELYLGKQNK
                     NMKLFKVDRFDK"
     gene            13141..15054
                     /locus_tag="PC494_000109"
     CDS             13141..15054
                     /locus_tag="PC494_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDF3910643.1"
                     /translation="MKYGGIIMKEILVIAPTKGTYEKSIHIVKKNKYTNIDVVFGNLK
                     EGIPLAEKSINHGTRIIISRGGTYNMLKATYNIPIVEIKVDAYDIIKSYKEVKNSNEP
                     FGIIGFNNVIYGFDIIEEILNKKITMIEIEKEEEIYDAIEKYRKKGINTYIGDTTVAH
                     IVKRLNCKGILIESREENILRAIQQAEQILEATKDEQKRRLQIEAMTDFVHDGIITVD
                     KNFKITLFNKSAEKIFGIKKENALYHNVVDVIPNTVLPQVVETMEPQIGEIQNIGSTK
                     IITNRVPIIVDGQIQGAVSTFQDSKEISSFEHTIRRSLLSKGLSAKYTFDDIIHASEK
                     TKDCIELAKKYACYDTPMIITGESGVGKELFCQSIHNYSKRKNAPFVAVNCAAIPPSL
                     IESEFFGYEEGSFTGARKKGKAGVFELAHEGTIFLDEISEIPLELQGRLLRVLQEKQV
                     MRIGGDKVIPIDVKIICASNKDLKNMMRNGLFRQDLYFRINILTLYLPSLKERKEDII
                     KLSEFFIHKYSSKYNKTPLIITPNIKKALLEREYEGNIRELEGMMERAVIVESFDSIL
                     LEKLSNEYTNNIVDKDNSDFECSNLDLKTLEKKYIYKIYNENNRNTTKTCEILKITRS
                     TLWRKLKEIEDDV"
     gene            15325..16299
                     /locus_tag="PC494_000110"
     CDS             15325..16299
                     /locus_tag="PC494_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-keto-3-deoxygluconate permease"
                     /protein_id="HDF3910644.1"
                     /translation="MHILKSVKKIPGGLMVCPLLFGALFNTVCPQALEIGGFTTSLFK
                     TGAMSILALFCLCNGAQINIRQAGKPLTKGIVLTATKFIIGAVLGIIVSKFIGPKGII
                     GITPLAIVATMTNSNGGLFAALAGEYGDSTDVGAISILSLNDGPFFTMLAFGVTGLAN
                     VPIVALFAALIPILLGFILGNLDEDIREFLAPGTTLLIPFFAFPLGAALNFNQIITAG
                     LPGVVLGLGVTIITGMGGYFVMKLIRAEHPAVGAATGTTAGNAAGTPEALAAIDPTLA
                     TIAAVSTVQVAAAIIVTAICCPMLVSYLDKREKKKKSIFKTNKNIEVN"
     gene            16320..16595
                     /locus_tag="PC494_000111"
     CDS             16320..16595
                     /locus_tag="PC494_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UxaA family hydrolase"
                     /protein_id="HDF3910645.1"
                     /translation="MNAIIHANEKDNLVTCVRPLIKGEKVSIDGKSYIVNDNIPVFHK
                     MATEDVKKGDVVYKYGEIIGIATVDIKTGDYVHVHNIESTRGRGDKK"
     gene            16608..17771
                     /locus_tag="PC494_000112"
     CDS             16608..17771
                     /locus_tag="PC494_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UxaA family hydrolase"
                     /protein_id="HDF3910646.1"
                     /translation="MKLMGYLRENGQFGIRNHVLIIPTSVCSSETATRIASLVPGAIA
                     IPHQHGCCQIGSDIELTAKTLIGFGKNPNVAAVLVVGLGCDGIQAKELASEIATTGKK
                     VDYVVIQECGGTLKTVSKGAEIVSKMAREVSKEVRVEFGMSEITLALECGGSDPTSGI
                     ASNPSIGVASNLLVDEGGSSILSETTEVIGAEHLLATRFEDEEMKDKFLKFVSDVEKR
                     AIAMGEDLRSGQPTPGNKAGGLSTIEEKSLGCMYKAGNKPFKGALEYADIVPPDKKGL
                     YFMDTPGQDIDSITGMVAGGAQIVIFSTGRGTPTGSPISPVIKITGNSDTYNKMPDNI
                     DINAGRIITDGAKIADIGQEIFNEIIEVCNGKHTKAESLGHREFGIYRISSTF"
     gene            18108..20387
                     /locus_tag="PC494_000113"
     CDS             18108..20387
                     /locus_tag="PC494_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HDF3910647.1"
                     /translation="MNFENTKNKKIIATLLLTLLLIVSLTCVTFIMNLNKVTHNETER
                     YLVEVSQSISTTINVKCKSIFRTLYSTGDTYFEINDSEKEVNKYLSKKLQLFEFDWLG
                     IIDSNGNFISALKDTGNVKGQDFYRKALQGKETITPVKSQSGTYGILYSVPLYKGDKI
                     VGAVAAWNTIDTMRNLLSVESFHGEGFSQIIDQDGNFIVSSANKNAPKNVVNFFDMIK
                     HQGKQVDKNKLEEMKINLKKNKTGSIYYTLNDGISKAMHYLPLQEENLYLLSVVPTKT
                     ASAQFDLLLKKAIFINILIVILFLLLIILIMFINQKNRAQLIKIAYVDSVTKGYSKAR
                     FDMEAKKIIQSSSSESYSLVSINIQKFKLINDSFGSEAGDKTLKYIHDVISNYLEPGE
                     LLCRVSNDQFNVLIKTIPQKEILKYIENITNDINSFNKNEECKYFIALSIGVYKIDDP
                     NLPLVSIQDRANVARKNNKGNIGNHPLYTCVFYSDLERLKMIKEKEMENRMEEALNNN
                     EFIVYLQPKISLKDNTIVGAEALVRWQDPNKGLIPPDEFIPFFEKNGFITKLDHYVFE
                     KVCSMIRKWIDNGETPIPVSVNFSRANLNNIDFLEKYRMLRNKYNIPAKLLEIELTET
                     LVFENLQKLINIIDQIHEEGFQCSLDDFGSGYSSLNMLKEIKVDTLKLDRAFFSSPNA
                     DNIAENHVIESIVNLAKKLNMNSISEGVETILQMDYLKKINCDMIQGYVFSKPLPQEI
                     FEKMTFGKKLEETSMDSSV"
     gene            complement(20482..21822)
                     /locus_tag="PC494_000114"
     CDS             complement(20482..21822)
                     /locus_tag="PC494_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HDF3910648.1"
                     /translation="MENQEALRHEKIWILLFRYSIPAIIAMMVTSLYNVVDRAFIGSM
                     EGIGSIAIAGLGVTMPVFTLIIAFGMLVSVGASTRLSIKLGERNREEAEKILGNALTL
                     SIIISLIITILGLVFLEEILFILGASKDSIFYAKDYMSVILVGSIFNLVAFSLNNAIR
                     AEGNPKLAARTMIVGCVLNLILDPIFIFVFNLGIKGAAIATVLCQIVVFFWVIHYFIR
                     GKSNLKLKKCNLKLNKDIVKKVFAIGMTPFAMEVAISITHMFTNNSLKVYGGDLAIGA
                     MTALTSILLMFMMPVFGLNQGMQTIISYNYGAKQYERAKKTLILSIIVSVVILSFGFL
                     VVQVFPEVFVGIFNKDSDLMDIAVRGISLNLITLPIMGISIVGPVYFQCISKVKHSMF
                     LTLLRQFILFIPLIIVLPIQFNLDGVWLAQPVADFIAMIIVLLFLKREFKTSRV"
     gene            complement(21834..22616)
                     /locus_tag="PC494_000115"
     CDS             complement(21834..22616)
                     /locus_tag="PC494_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004460318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF3910649.1"
                     /translation="MNCINTKNLNVSYGNTDIIKNLNLNIPKGKITTIIGANGCGKST
                     ILKTIGRIISPNSGKIYINGEDIYKKKSKEIAKDMAVLPQSPQAPSGLTVSELISYGR
                     FPHKSGFGNSSKEDREIVNWSLEVTGIAEFKDRNMEDLSGGQRQRAWIAMALAQETDI
                     LLLDEPTTYLDLAHQLEILKLLDELNKKQGRTIVMVIHELNNAARFADHMIGIKKGKI
                     VCEGDAYDVMTKDNLKELFNIDAEIATDPRTNKPICITYDMV"
     gene            complement(22631..23653)
                     /locus_tag="PC494_000116"
     CDS             complement(22631..23653)
                     /locus_tag="PC494_000116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HDF3910650.1"
                     /translation="MKNIIKINSKTLLVISILMVLIFITFLLSLNMGSFSIEPMDVIK
                     TFLGQGQRNHEIAIFKLRLPRIVIALLVGSALSTAGVILQGVTKNDLADSGILGINSG
                     AALFVVVYIYLMNGNVYEGMSNLTVFTMPIVALIGALFGAFLIYSLAWKGGINSSRLL
                     LIGIGVNIAFTSILTIFQLKFTTQEFNRVMAWTSGSIWGTSWKYVIAVLPFIVIFMGI
                     TIYKSKYIDVLNLGDEVSISLGVDVEKQRRRLIIYAVILSGVSTAVAGSISFLGLIAP
                     HIGRKIIGPKHKRLIPVSALIGTLLLLIADTISRNLLAPIEIPVGIVVSIIGVPYFIY
                     LMLVND"
     gene            complement(23659..24672)
                     /locus_tag="PC494_000117"
     CDS             complement(23659..24672)
                     /locus_tag="PC494_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HDF3910651.1"
                     /translation="MTKLSKKNITYLLILVSIVVLVFGIVLSITIGAKDMNLSTVIDS
                     LIKMEDGINMRIVKDVRLPRAIAAALVGGFLAVSGAIMQGITRNPIAEPSVIGITQGA
                     TFAISISLVLQKKLPQLIHGSFSVMMFAFIGASISGLFIYFISSKSRGRVNNVKLALA
                     GVALGTLLISLASAISMYFNLSQQLSFWISGGLVGVKWEGIKLLFIAGGIGFILAIIM
                     APRITILSLGEEVAIGLGQKTNFVRFICIVLVILMTGASVSVSGNIIFIGLIVPQIAK
                     GIVGSDYKYIIPSSLVLGAVLLVYTDILSRMINPPYETPVGSITALIGVPIFIYLVRK
                     GEK"
     gene            complement(24800..25738)
                     /locus_tag="PC494_000118"
     CDS             complement(24800..25738)
                     /locus_tag="PC494_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDF3910652.1"
                     /translation="MKKIKSLAIFISIITTLVLVTACSDKNTEDKDKSETRVVQSVKG
                     EVKIPSNPKKIVDISGSSEELLLAGYKPVATANVDSYETDKLPSYIREELKGVKIVGH
                     SMMDTMDMEAILEVNPDLIIMSQRQEKIYDQLKEIAPVVMMKDYANDWRSKLTDVSKL
                     FDKEEEAKSWLQKYDEKATKLGKEVIEKNGEKTYLPVLASSGQFMVFSDGGIGTLIND
                     DMKLARPKNMPKQDGITLPMVSMEGLTDIDADHIVVIATESDKKDLENSAIWAQIRAV
                     KDGNVTILDAAPFFSQSYNPIGKELLLESVKNELTK"
     gene            26008..26472
                     /locus_tag="PC494_000119"
     CDS             26008..26472
                     /locus_tag="PC494_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016208838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3910653.1"
                     /translation="MVHLVYCDNAGKKGEKVLDKILAGTKTMVIRGAAGRKIPHSRVF
                     EDELLYFMEKGTAKISAKATVKKVENYVKLTEDEISKILNENQPKLNLSEKQKVRWHK
                     KCLCLVEFENVEEITPLDFDHQGNMDDWLIVEKIEDVVVGTSIPYNYEKSKF"
     gene            complement(26584..26901)
                     /locus_tag="PC494_000120"
     CDS             complement(26584..26901)
                     /locus_tag="PC494_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HDF3910654.1"
                     /translation="MDEKMIEISFGIIGFAGDAKGLAFEAIKEAKSGNIDKARECIEK
                     SKESIHKAHKFQTELIQNEANGNKTEISVILIHAQDHLMTAMNFQQLAEEFIDVYERL
                     ESK"
     gene            complement(26914..27645)
                     /gene="chbG"
                     /locus_tag="PC494_000121"
     CDS             complement(26914..27645)
                     /gene="chbG"
                     /locus_tag="PC494_000121"
                     /EC_number="3.5.1.105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chitin disaccharide deacetylase"
                     /protein_id="HDF3910655.1"
                     /translation="MTKIIINADDFGYCEAVNYGIISAHNNGIVRSTSMMANMPGVEH
                     GVGLLKENKTLNCGVHMTLSCGRPLLSNLKTIVDKDGFFIRRITDEIIEKMDCDEIYR
                     ELCAQIDRVKGLGIDISHLDSHHHIHTLVSLKPVIEKIVTKYNLPIRGGFEYNLEYSK
                     VVPLIDSFYKENVSEEYFIKNIDEIMKYDVVDIMSHPAFLDDYILNSTSYAIDRTKEH
                     KILTSKKVKEFLEKNGLVISSYRDI"
     gene            complement(27671..28981)
                     /locus_tag="PC494_000122"
     CDS             complement(27671..28981)
                     /locus_tag="PC494_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HDF3910656.1"
                     /translation="MKKGLKIVTIGGGSSYTPELVEGFINRYEELPVKELWLVDIEAG
                     KEKLEIVGNLAKRMVKKAGVDMKINLTLDRREALRDADFVTTQLRVGLLDARIKDETI
                     PLSHGVMGQETNGAGGLFKALRTIPVIFDIIKDVEELCPNAWMVNFTNPTGIITEAVF
                     KYTNFRRYIGLCNVPIHLKNDVAKLFNVESDRISMDFAGLNHMVYGLNVSLDGEDVTK
                     EAIDKFVKADISMQNIKAIDFNAEFVKSLGAIPCPYHRYYYKTKEMLEDELREFKEGK
                     ARGQVVKELEEQLFELYKDEKLDVKPPQLEKRGGAYYSDAACNLISSIYNDKKDIQVV
                     NTLNKGSIRDFKDEQAVEVSSVITKNGPKPISIGYLPDSVHGLVSQIKSFEVLAAKAA
                     VYGDYESALLALCINPLIPSDDLAKTILDEMLEAHKDYLPRFNR"
     gene            complement(29078..30391)
                     /locus_tag="PC494_000123"
     CDS             complement(29078..30391)
                     /locus_tag="PC494_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDF3910657.1"
                     /translation="MEKFMSFMDKYIVPVAAKIGAQRHLVAVRDAFIVMIPITMVGAL
                     GTLINNLPLEAYKNLMASIFGENWTTFGGDLWWGAIGTMAVFLVIGVAYFLAKSYESD
                     GLQSGLIALSIFFIMAPQIGKIVPEGGTTVVEGWGMIQQTYLGTAALFSSILIGLLST
                     EIFVRLSKVKKLTIKMPDGVPPAVSRSFAKLIPGMLTIMIFTVIGIFIKMLSNGSFLT
                     DILNTYLGAPLSNVADSLGSTMLIAFIIHILWTVGLHGANIALPFTETILMKLGGENA
                     ALAQAGATEGYHVLAGAFFDAFVYLGGSGMVLGLIVALLIAGRRRKEMIVLGGPPAIF
                     NIGEPLIFGLPIVLNPIFMIPFVLAPVICSAVSYLAIDFGLVAPVILPKIPWVTPPIL
                     GGAMATGDWTGGALALFNLILSILIYIPFVIASEKMEANKLKINN"
     gene            complement(30413..30724)
                     /locus_tag="PC494_000124"
     CDS             complement(30413..30724)
                     /locus_tag="PC494_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDF3910658.1"
                     /translation="MIKIMLACSAGMSTSLLVTKMEDAAKENGIEAKIWAISEVNLKN
                     EIENCDVLLLGPQVRYVLGKATEMAKPYNIPVEVINMMDYGRCNGKAVLDRAVELNSS
                     K"
     gene            complement(30924..31628)
                     /locus_tag="PC494_000125"
     CDS             complement(30924..31628)
                     /locus_tag="PC494_000125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDF3910659.1"
                     /translation="MKEPIYKVIENHVRELINSDSLKEGDLIPSEKQLSEEFNVTRMT
                     VRSALNNLVKEGYITRQRGVGSIVIANNIYDNISSVSGFTKEMESKGYKVSNILVSLE
                     IVQADENLSSKLNISLEENVWEIKRVRLANDARVSYMITYMPVKLFPNLNKTHCENSL
                     YNFVEEVCGYKIAMSEREVQAVISNEECMDNLKLEEPEPLLYISQICKLQNSEIFEYS
                     HTYHYGYTLTLNAVVE"
     gene            complement(31719..33080)
                     /locus_tag="PC494_000126"
     CDS             complement(31719..33080)
                     /locus_tag="PC494_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HDF3910660.1"
                     /translation="MKDRLNLTEGRITEKLLKLSLPIMGTSFIQMGYNMIDMIWVGKA
                     GSKAVAAVGTAGFFPWLAMAFIMISKVGGEIKVAQSIGANNISTTKSYMKSAIEINII
                     LAIIYTISLIVLNKQLIGFFRLGDLEVITMSRQYLIIVALGMVFYFINPVFTAIFNGL
                     GNSKTPFRINTVGLITNIILDPILIFGWGFAPKLGVAGAAIATVFAQIVVTTCFIYII
                     VKSKEEYFKLRLFKEIETKYYKVLYKLGLPIAIQSGMFTVFSMLLGVIVASWGPVAVA
                     VQKVGSQIEAISWMTAEGLSVALGSFVGQNYGAKKYSRINKGCKIAITVSSVLGIITT
                     LVLVFAGESIFSIFIDESEAIEKGAVYLKILGYSQFFMCLEIITTGAFKGLGRTYIPS
                     IIITILTGARVPLAYFISRPEMLGLNGVWWSITLSSILKGILMISLFISLLKLGKLYK
                     ISE"
     gene            33579..34733
                     /locus_tag="PC494_000127"
     CDS             33579..34733
                     /locus_tag="PC494_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HDF3910661.1"
                     /translation="MKINKKFNRVDMQVSILTAIIVIISSSCVYFFNYTLTYKSMIYS
                     LSERSKHIYEYVERNIDKNTFTEINSKEDQSKKSYKSSKILLESVKNTTGVMYLYTAK
                     KTKDGSLVYVVDGLNSSRSDFRNAGDLIEKEIWGDLNKALDNHILLPKKIKSTSWGYI
                     FISYFPIHNDVGKVVGVIGIEFEAKHQYNTFKFISIVTPIIALLTCLISALIAVILFK
                     RISNPTYTDFANTDYLTGLKNRNAFEIDMNNLNNSNLKNLISIISIDLDGLKKINDKF
                     GHQTGDLYIKQASKIIQYVINKKYIVYRIGGDEYIIILKNLSHKEINNIINNINLKIV
                     EENSTNELKLSMSIGYAIFDEKVDVSLFDTYRRADSQMYDNKRKINKQYQ"
     gene            complement(34815..36533)
                     /locus_tag="PC494_000128"
     CDS             complement(34815..36533)
                     /locus_tag="PC494_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative 2-aminoethylphosphonate ABC transporter
                     permease subunit"
                     /protein_id="HDF3910662.1"
                     /translation="MNNNAISSKSISLKSKMNLDIKKCMLTVLVMSLVIFLLAPIIYL
                     FVQAFLDKDGVFVGLQNFQEYLASESLLNSLKNTVFVSVISTVISLTLALVYAYALTR
                     TKIKFKGFFKSLAMFPMFAPTMMHAIGLVYLFGNQGLVTNLLGVHVPIYGAVGIILAQ
                     IIYVFPQSFQILYISLSSTDYRLYEASNTMGISKIREFISITIPSIKYSLISSAFVSF
                     TLCFTDFGAPKVIGGEFNVLSIDVYKQIIGQQNMPMGATVSILLLIPAIISFIVTKKI
                     EKNQNSYITSKSIPYKVKTNKLRDSILGGVVGIIAFGIIAVMLTVILSSLISVWPYDL
                     RLTLEHFSMKNSIDGIKPFINSIKMSLLTAILGTSFVFLFAYLNEKTEKAPYLKSFGY
                     FLSTLPMALPGLVLGIAYVLFFNKLEFNFMDTIYIKNLFNGLYGTLLIMVICNIVHFF
                     SVAFITATTAIKKVDKELDMVAKSMGINSASILKNVTIPLCLPAVLENFMYFFLNSMV
                     TISALVFIYTASSKVAAISIVQLDDKGSTAQAASLAVLILVTNILVKVIYEFIKNRLE
                     KRTNFN"
     gene            complement(36538..37527)
                     /locus_tag="PC494_000129"
     CDS             complement(36538..37527)
                     /locus_tag="PC494_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDF3910663.1"
                     /translation="MSYLKINNVFKSYDQKRVLNNISLDIEEGEFLCLLGPSGCGKTT
                     LLRIIAGLEDVNSGTIILQDKDITNLEPSKRGFGIVFQSYALFPNMTAYNNIAFPLKE
                     RKVSKGKIDNKVKEVLETVGLTNEAHKYPKALSGGQQQRIAIARALALEPKFLLLDEP
                     MSALDAKVRHKLRMDIKRLQKELNITTIMVTHDQEEAITMADKIAILNGGDIMQIGTP
                     EEIYQNPQNLFTAQFIGDTNCFDNGDSILTVRPEYVQIEKSTKENYQGIISNIEFRGN
                     LLRVEIKDKLNENFIISDASIKEWVNLNLVEGDLVKISIDEKYYLKYPKVKGA"
     gene            complement(37623..38672)
                     /locus_tag="PC494_000130"
     CDS             complement(37623..38672)
                     /locus_tag="PC494_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative 2-aminoethylphosphonate ABC transporter
                     substrate-binding protein"
                     /protein_id="HDF3910664.1"
                     /translation="MKEFIFTCLCIVVITFMTSCISTTPQTTQGKGNNKLTIYAALEE
                     EQIAYYMEGFREEYPNIDVEIVMDSHGVIASKLLAEKDNPQADIIWGLSAMNMIELKK
                     DGALEAYKPKNYDKVDKKFKDTEDDVSWVGMSVPETAIVVNYKELKKLGIDIPKSYED
                     LIKPEYKGLITMPNPASSGTGYLTVSGLIQMMGEKDAYNYMDKLHKNIATYTHSGSKP
                     AKLAGSGEYPIGITLGYRATQQLSSGEPIEVVFPKEGSGWDLEANALVKKDNIKKEAK
                     LFLDWAISDSAMDRYAHEVAVTSIKTDNPVPKGYSKQPFEQLIKEVDLNSAAKNRSTV
                     LKTWESKYGSKSESK"
     gene            complement(38949..39617)
                     /locus_tag="PC494_000131"
     CDS             complement(38949..39617)
                     /locus_tag="PC494_000131"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit D"
                     /protein_id="HDF3910665.1"
                     /translation="MARLNINPTRMEMTRLKKLLKTATRGHKLLKDKLDELMKQFLEI
                     VRENKRLREEAENALDTAYKNFIIARAVMSQEYLGSALMMPKQSVSVDVSTRNIMSVD
                     VPVFDFKTENNQSDIYPYGLAFTSGELDSAMEAFSDAMQPLLRLAESEKSAQLLAQEI
                     EKTRRRVNALENVMIPNYIETIKYIAMKLEENERASTTRLMKVKDMVLKKALEEKKKN
                     DLVV"
     gene            complement(39623..40996)
                     /locus_tag="PC494_000132"
     CDS             complement(39623..40996)
                     /locus_tag="PC494_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit B"
                     /protein_id="HDF3910666.1"
                     /translation="MIKEYKSIQEVAGPLMLINGVEGVKFDELGEIELSNGEIRRCKV
                     LEVNGDTALVQLFESSTGINLAESKVRFLGKSLDFGVSPDILGRVFSGMGRPIDGGPE
                     IIPDKRLDINGAPINPAARDYPAEFIQTGVSAIDGLNTLVRGQKLPIFSGSGLPHANL
                     AVQIARQAKVRGTDSKFAVVFAAVGITFEDAEFFISDFKATGAIDRSVVFVNLANDPA
                     VERVSTPRMALTAAEYLAFEQDMHVLVIITDITNYAEALREVSAAKKEVPGRRGYPGY
                     LYTDLATMYERAGKMKGHEGSITMIPILTMPEDDKTHPIPDLTGYITEGQIILSRELY
                     KKDIQPPIDVLPSLSRLKDKGIGKGKTREDHADTMNQLFAAYSRGKDAKELMAILGES
                     ALSEIDLMYAKFADEFEKEYVSQGFRTDRTIEQTLEIGWKLLSMLPKSELKRIRDEYF
                     EKYMPKE"
     gene            complement(40993..42771)
                     /locus_tag="PC494_000133"
     CDS             complement(40993..42771)
                     /locus_tag="PC494_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit A"
                     /protein_id="HDF3910667.1"
                     /translation="MKTGTIVKVSGPLVVAEGMRDANMFDVVRVSDKHLIGEIIEMHG
                     DKASIQVYEETSGLGPGEEVVSLGMPMSVELGPGLISTIYDGIQRPLEKMYDISGTNI
                     TKGVEVSSLDRTTKWEFKPKKSVGDKVVAGDIIGGVQETAVVECKIMVPYGVKGTIKE
                     IYSGEFTVEDTVCVITDEKGNDIPVTMMQKWPVRKERPYREKKTPDSLLVTGQRVIDT
                     FFPITKGGVAAIPGPFGSGKTVTQHQLAKWADADIVVYIGCGERGNEMTDVLLEFPEL
                     KDPRTGESLMQRTVLIANTSDMPVAAREASIYTGITIAEYFRDMGYSVALMADSTSRW
                     AEALREMSGRLEEMPGEEGYPAYLGSRLAQFYERAGKVNCLGMDEREGTLTAIGAVSP
                     PGGDTSEPVSQATLRIVKVFWGLDASLAYKRHFPAINWLTSYSLYQEKVDVWADKNVN
                     DNFSAQRAQAMKLLQVESELQEIVQLVGVDSLSDGDRLILEVTRSIREDFLHQNSFHE
                     VDTYTSLHKQYRMMGLILKFYKSAQDAIKQNVTINDIIKLSVLEKIGRAKYVEEGDID
                     AAYDSIEDEIDNELADLIKKRGAEEL"
     gene            complement(42888..43211)
                     /locus_tag="PC494_000134"
     CDS             complement(42888..43211)
                     /locus_tag="PC494_000134"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit F"
                     /protein_id="HDF3910668.1"
                     /translation="MLMYKVGVVGDKDSIMGFLALGIDIFPAYDSDEIKKSIHKLVED
                     EYAIIYITEQASLLAKESIAKYKDYQLPAIIVIPGIGGSMGLGMNEVRESSKRAIGAD
                     ILFKE"
     gene            complement(43198..44175)
                     /locus_tag="PC494_000135"
     CDS             complement(43198..44175)
                     /locus_tag="PC494_000135"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit C"
                     /protein_id="HDF3910669.1"
                     /translation="MAEEKTYPYAVARIRVLEKQLLNRQMFIQMAEAKSPEDSLRIIA
                     EAGYADTSNNNIHNFENILTQELSKTYEILKSLAPEEKFVDVFLYKNDYHNLKVLIKE
                     EISGVDGEKYLIDGGTIPLIKLRESLANRSFSDLPKIMSSAILEAFDVYNKTQNGQMV
                     DIVLDKATFTSMKETAKESQNKFVIDYVMKVCDLTNLKSFIRVKNMKKDFDMFMNVFV
                     SGGSLDKEKFLEAFSSDTPASCFKSTSYSDVCKNGMDSGFTVFEKLCDDYLMEYVRGA
                     KFKPLTLEPLIAYLYAKESEIKTIRIILTSKLNNIDADTIKERLRDAYV"
     gene            complement(44190..44753)
                     /locus_tag="PC494_000136"
     CDS             complement(44190..44753)
                     /locus_tag="PC494_000136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit E"
                     /protein_id="HDF3910670.1"
                     /translation="MGNEQKMIDRIIADAKQEAQEILDKAKSEADLKVNSANEKAEKE
                     MASYTKLAEAEAEKAASKEISGAYMEAKKQILSKKQEILEEVILEAKNKLLNLKDNEY
                     EEIILNMIEKSNCTDDSEIVLSKKDKKTLKDVLSKKGIKVSDETRDITGGFIVKKGDI
                     EYNYSFEAIIAVEHEYIEQIAAEILFN"
     gene            complement(44805..45296)
                     /locus_tag="PC494_000137"
     CDS             complement(44805..45296)
                     /locus_tag="PC494_000137"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit K"
                     /protein_id="HDF3910671.1"
                     /translation="MEFLNALGNGQFLAISGAAIAALFAGMGSAKGTSIAGQAAAGVV
                     TEDPSKFGQLLVLQLLPGTQGLYGFIIAFLILSKAGIIGGDAIPTSAQGLQLLMAGLP
                     IGLVGLVSGIAQGKAAAAGVGIVAKRPEELGKAITFAAIVETYALLGLLVSFLAYNGI
                     AIG"
     gene            complement(45299..47224)
                     /locus_tag="PC494_000138"
     CDS             complement(45299..47224)
                     /locus_tag="PC494_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit I"
                     /protein_id="HDF3910672.1"
                     /translation="MAIVNMNKISIVGLEAQKSQILKLLMNRGFVQIDDSAFLTEEEE
                     LKNYLVKDSEESEVIMLEQKMSHVNQAINIVSSLVKQKKSLLAPKREFNKIDSEKEGQ
                     VYAEALELNNLHKEIGTIRSNINLLNNNKSMLEPWVNFDIPLENMETKYTKTILGTVP
                     ISANIDALRVKLEDEIPESVIGIVNSDKLMNYVYLITLKETFDDVLEVLKEFNFSVVS
                     LPNEEGTPLQAIKKYNEMIIRQENVSKDKTEEIKRHADSIHMLENLYDFYTIERDQKK
                     IIERLVKTKTTFCLNGWLPSKRADELIKEITEKFNCCVQTEEGSKEEGFPILLENNKL
                     VTPFESVTNMYSYPSTKDIDPNTILTFFFVVFFGMMLSDAAYGLIIAVVCGFVVYKLK
                     IQKGEGNLIKLIGICGVSTTVWGLIFGGILGDLIPIKALINPLEDVMTLMGMSLLFGI
                     IHIYVGLGIKAYTLIRSGKVIDAIFDIGFWYLCITGVCLLIIPFVAGDIGVFSEVGKY
                     LAIIGAIGLVLTQGRSFKGIPVKLFKGFSSLYGITSYFADILSYTRIMALCLTTGVIA
                     QVINLLGAIAGPILAVVIGVVGHTINLLINALGAYVHTSRLQYVEFFNKFYEGGGVPF
                     VPFKYKTKYTSINKKEM"
     gene            complement(47226..47537)
                     /locus_tag="PC494_000139"
     CDS             complement(47226..47537)
                     /locus_tag="PC494_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3910673.1"
                     /translation="MAFEIIKSIVEAEQTADSIKVKAVTDAESIRADAVNKCESIFAD
                     VKKQAKLMEETLIEKAVTDSRAEVDKILANAKSECLKIEKTAEERKSKAIEAVIGKVV
                     R"
     gene            complement(48167..48442)
                     /locus_tag="PC494_000140"
     CDS             complement(48167..48442)
                     /locus_tag="PC494_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif11-like leader peptide family natural product
                     precursor"
                     /protein_id="HDF3910674.1"
                     /translation="MNEKLTKILEEAKNDDEFRKELIKTREQRDVMDSFCKVVTSRGY
                     DMTVGELFSMGEEYTSNLLKSVNGGAAYPIEDWSDWYEDFFIMLSNI"
     gene            complement(48557..49966)
                     /locus_tag="PC494_000141"
     CDS             complement(48557..49966)
                     /locus_tag="PC494_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase/peptidoglycan binding
                     protein"
                     /protein_id="HDF3910675.1"
                     /translation="MIDGKEVKQESGQKNLKFKIAIVVGVLFVAYIGMAIFFRNHFYF
                     GTTINGVKASGKTVEQVNDLLTSSTNSYTLNLEERNNKKEQIKAKDIDLKFTPDDKVQ
                     KIKDSQSAIGWIGGIFKSKEYNNMITLSYNKDLLEKRFNALSCFDSKNVVEPKSAYPK
                     YDSTKNAYVIVPEVLGNKVKKDDFYKLVQNSINSGNTSISLDESKVYEAPNNTKDSEK
                     LKQAIKTLDKYVGVVVTYDFSDRKETLDGSEINKWLKVDSEKNYDITFDNDAMVEYTR
                     GLSKKYSTFGDSRPFKTATGKDITISGGIYGWLIDKKKEAEALVDVVKAGKNVTREPI
                     YIQKAVSRNKDDIGNTYVEISLSGQHMWFFKNGEMLVSTDVVTGDLARGFATPSGIYP
                     LNYKARNVSLTGQGYSSPVSYWLPFNGNIGIHDATWRNSFGGSIYKSSGSHGCVNTPF
                     SKAKKIYENIEPGTPIILY"
     gene            complement(50337..50999)
                     /locus_tag="PC494_000142"
     CDS             complement(50337..50999)
                     /locus_tag="PC494_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA-binding protein"
                     /protein_id="HDF3910676.1"
                     /translation="MIDISIDDKLKERWPNAKLGCIQAKVAVNKSSEKLINEINEFCD
                     TINQSLKVEDITKLDKIKDARNAYKELGKNPSRYRTSSEALVRRIIQGKGLYTINNIV
                     EINNLISIKSLYPVGTYNVSKLHSPVCFTVGDEGEQYKGIGKELINIENLPILSDSVG
                     KFGSPTSDSERAMITEDANEILICIFSFSQESDIEEYFGYAKELLKEYADGKDIETKI
                     IK"
     gene            complement(51253..53472)
                     /locus_tag="PC494_000143"
     CDS             complement(51253..53472)
                     /locus_tag="PC494_000143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HDF3910677.1"
                     /translation="MTGRNKSFTLITILFLTSLFLTMGYIYIEDTKHLLMSEAKIHIK
                     EVAVQGSQLAQRQIEKDLDVLNIFSNYYASNPDIPNEEKMKNLLDEMENQKFYTMAIV
                     DINGNAENTKGDKFSVKDREFFKNSIKGKKYVSSPYVDEVNKSIKKIAISVPLLNNDK
                     VVGVLYCTYNINTLMKLINISFYENNSISYVVKNNGTIILHPQGDSLSKNIYKLLKQD
                     NDIQEVNRLKKELQENKTGATVLNMLEERRYLGYATMDNGNSENNYIKDWNLIFSIPE
                     TVVFSNSKQIINRAVYAVLSIVLIFIAIIFYIIYIKKSNEKEILSLAYEDKVTYIGNQ
                     NKFYRECSKYLLDKPSLNYIIVYFDINNFKMINDTFGYEFGDNLLITIAKALKEELTE
                     GEVYARLSSDYFAIFCDYKNGRNKIIRKLDNIRSNIESNLSIVFEISLCVGIYFVEEG
                     EVDIQKAVNKANMARSVAKGKNINYAIYNEDVRNKLSEESMILDDIKIALVKNQFEVY
                     YQPKFSLVTGEMIGSEALIRWNHPEHGFISPAVFIPIAEKSKLILKIGRFVFERVCND
                     LYEWKKQGKKIVPVSVNLSRVELYQPDIVKFINKTIKMYNLSSDFIEIEITETVAINE
                     LNILKNVLNELRTYGFSISMDDFGTGYSSISCLRDMPIDILKLDKSFLGGIEHDERSR
                     NIAKSIVSLAKSLDLVVIIEGVESKEQAELMKQFGCDLVQGFYFARPMPAKNFLDLL"
     gene            complement(53748..56402)
                     /gene="adhE"
                     /locus_tag="PC494_000144"
                     /gene_synonym="adhC"
     CDS             complement(53748..56402)
                     /gene="adhE"
                     /locus_tag="PC494_000144"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HDF3910678.1"
                     /translation="MAHKEQVIIENKKENEVMSVGLDTVNNVESLVKKLAKIREAQKI
                     FATYSQEQVDKIFLAASLAANKQRVPLAIMAQKETGMGIAEDKVIKNHYASEYIYNAY
                     KETKTCGVIEKDEAFGMTKIAEPIGVIAAVVPTTNPTSTAIFKALLALKTRNGIIFSP
                     HPRAKNSTIEAAKVVLEAAVLAGAPEGIIGWIDEPSLELTTTVMKEVDLTLATGGPGM
                     VKSAYSSGKPAIGVGAGNTPAIIDDSADIKTAVNSILVSKTFDNGMICASEQSVIVLE
                     NIYNEVKKEFKERGAYLLDKDETEKIRNIILVNGGLNSKIVGQTACTIAKLAGFEVPV
                     DTKVLIGEVESVEIEEAFAHEKLSPVLAMYKASDFDDAVRKAEKLVEDGGFGHTSSLY
                     IDDVNQREKLDKFTSAMKTCRILINTPSSQGGIGDLYNFKLAPSLTLGCGSWGGNSVS
                     ENVGVKHLLNIKTVAERRENMLWFRAPEKVYFKKGCLGVALKELKDVMNKKRAFIVTD
                     TFLYNNGYTKAVTDLLDEMNIKYTTFFEVEPDPTLECAKIGAKAMREFNPDVIISIGG
                     GSAMDAGKIMWTLYEHPDVDFQDLAMRFMDIRKRVYTFPKMGEKANFVAIPTSAGTGS
                     EVTPFAVITDQDTGVKYPLADYELMPNMAIVDSDMMMNMPKSLTSASGIDALTHALEA
                     YVSMLATDYTNGLALQAIKSIFEYLPRAYDNGAKDPEAREKMANASTMAGMAFANAFL
                     GVCHSMAHKLGAFHHVPHGVANALLITEVMKFNSSDAPKKMGAFSQYKYPEALKRYAE
                     IASFLGLKGNSDEEKFQSLLVAIEDLKLKVGIPKSIKEFGVEESKFMDSIDEMVIQAF
                     DDQCTGANPRYPLMNEIKDMYLNSYYGR"
     gene            56906..57106
                     /locus_tag="PC494_000145"
     CDS             56906..57106
                     /locus_tag="PC494_000145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3910679.1"
                     /translation="MEKLKTISVFSLIISVILTIGGIGIVTYYVDNLFIRGLSVFVLI
                     MSSSFVSTTVRLIFEESKRYKF"
     gene            complement(57313..57903)
                     /locus_tag="PC494_000146"
     CDS             complement(57313..57903)
                     /locus_tag="PC494_000146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipicolinate synthase subunit B"
                     /protein_id="HDF3910680.1"
                     /translation="MRLEGLTIGVGFTGSFCTYDKIFIELENLVKEGANVHTIFSDVS
                     QNIDCRFGNSEEFMKKAYELTGNKPIVTIEEAEPFGPKGIADIIIIAPCTGNTAAKLA
                     NGITDSPVLMAAKGHLRNDKPLVISISTNDALSFNFKNIGILLNSKNIYFVPFGQDNC
                     KAKPNSMIAHTELIIPTIELALENKQLQPVIKSPHQ"
     gene            complement(57906..58781)
                     /gene="dpsA"
                     /locus_tag="PC494_000147"
     CDS             complement(57906..58781)
                     /gene="dpsA"
                     /locus_tag="PC494_000147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipicolinate synthase subunit DpsA"
                     /protein_id="HDF3910681.1"
                     /translation="MSNQYDITVIGGDLRQVYMVKKLINKGYSVVTYGISNEIINGIV
                     GKSTSLAEALSKSSIILCPIPFTKNQVNIENTDDCLDATIDNLLINLSPNQILFGGNI
                     PTKVCKFCEQHSIQIYDFMKMNDVAILNAVATAEGAIAEAIKRSIINIHQSNCLVLGY
                     GRCAQILAKKLYALDANVCVGARNNDARSTANAFGYSSISLSQLDEKLLQFDYIFNTI
                     PECILTKERLEKVSQEVTIIDIASSPGGVDYSVVKEAGINATLCLGLPGKYSPKTSGE
                     ILVNAIENIINERRD"
     gene            complement(58857..60248)
                     /locus_tag="PC494_000148"
     CDS             complement(58857..60248)
                     /locus_tag="PC494_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AMP-binding protein"
                     /protein_id="HDF3910682.1"
                     /translation="MNYYELLRIKKERQKNKNFLIIDGEKYTYENILSYSEELGKQIS
                     LGENIPILIYSKNIMFQLISFFAINYSKNIPIICHYNLSKKVLDDILLKNNISIIISD
                     ESMDVIDLYDDNNNEVAKKVNFSIFNPKFNIYMYQYKKLINYLDKSICMGALSSGSTS
                     VPKVLYRTYESWAGFFPIQNGIFNISGESILFVNGTLSFTGNLNSIMSVLYEGGSIVI
                     SSGLNCKSWIRTIKQYNVTNIYLIPTKLQLLVKHLKEPVLKVVSIFTGSQLLFEDTAR
                     NLKKYMPKSEIILYYGASELNYITYLCYDELIEKPLSVGRPFPGIDIYIREGKIFVNT
                     EYAVYNATKPYSVNDIGYYDNDGYLIFEGRSDDIINIGGFKVSSTKIENEVKKIPQIE
                     DAIVLPYSDTIRGNQIVLFVITIDKITKKDLLIKMKDNLMKNEIPKKIIFLNSFPYTS
                     SEKIDRLALLKML"
     gene            complement(60252..61388)
                     /locus_tag="PC494_000149"
     CDS             complement(60252..61388)
                     /locus_tag="PC494_000149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiolase family protein"
                     /protein_id="HDF3910683.1"
                     /translation="MKEVFILGGLRSHIGLKNGIFQFVQPELLGASVLKDLIKKYEID
                     KIDEIICGNAVGTGGNIARLMTLTAGVSNEVPAFTVDMQCASAMMSIDIAFSKVKSGQ
                     CDLIIAGGFESSSLQPMRTYHKNDKRYDTNNPNYTVAQFSPDDNSQNSMLEGAERVAE
                     LYQIEKADLDFWVKESHKRAKEAREEKILEDIISPINNSTYDEGIRDKMSQRLLDRMP
                     SILGKETITNAANSCLINDGASFIIICSKKYLEHVKKKPKAKIINTCTIGTDATLSPT
                     SAIQAMDKLLEIESLNYLDVSAVEFNEAFAVIDVLFQRKYPELIDRYNIFGGALAYGH
                     PYGASGAIIALHLLKALEKTKGRYGICSIAAAGGLGSALLLERV"
     gene            complement(61420..61965)
                     /locus_tag="PC494_000150"
     CDS             complement(61420..61965)
                     /locus_tag="PC494_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HDF3910684.1"
                     /translation="MKNTKVNIQDLTKMSICVALLCISSYIYIPLPFTPAGVTAQTIM
                     INLIALILTPRQAFSTVGVYIMIGLIGIPVFGGGTSGIGKLLSPTGGFYFGFLFAALI
                     ISLLKGRNNDIKRYILITIFVGMPIIYFMGTVFMCYFNQMTVEAALFAAVVPFLIGDT
                     IKSVIASFLGTKLNNVLRRNL"
     gene            62289..63068
                     /locus_tag="PC494_000151"
     CDS             62289..63068
                     /locus_tag="PC494_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3910685.1"
                     /translation="MKVNENNINNIDEELGELSRKVYLESPDFWISISDKIIDKVFDE
                     MLLFFAVKYNYFNIVCFAIENNYLDLNMPSKNKKYTNIMEHLLDTSKQNEDKKIYNYL
                     LSLNKGNNLDERPILDELNCNISSDTFEKKDIYLPKYLCPSCNSNIFDTGYKVSNDIT
                     YKFSSKEAEPIEMCSEVSSIRCCNCDELLEDITLDKLYNLCKIQNCNNCGSNLTKVGI
                     IAKKKMNFDENTEKFKDVSTSYCCGNCDSEISLSQREHFKI"
     gene            complement(63523..63951)
                     /locus_tag="PC494_000152"
     CDS             complement(63523..63951)
                     /locus_tag="PC494_000152"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HDF3910686.1"
                     /translation="MIKKLNNKDINKIMEIWEKSTIKAHDFISKEYWQNNYNTVKNEY
                     IPISDTFVYDDGDEIKGFISIIDKSFIGALFIKPKYQNLGIGGKLLDYATKKYKSLSL
                     AVYKDNKKAVVFYNKKGFNIVKEQVNEDSGFKEYIMEYSK"
     repeat_region   64140..65810
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=64206..64234
                     /rpt_unit_seq="atttacataccacttagttaatataaaac"
     gene            complement(65994..66260)
                     /gene="cas2"
                     /locus_tag="PC494_000153"
     CDS             complement(65994..66260)
                     /gene="cas2"
                     /locus_tag="PC494_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated endonuclease Cas2"
                     /protein_id="HDF3910687.1"
                     /translation="MFVIVTYDIVEARSLNRIRRILRKYLTWTQNSVFEGNITEGKLH
                     KCISEIENIIDNSEDSIYVYEIKNPNSIKKKCYGIDKYSDEMFI"
     gene            complement(66263..67243)
                     /gene="cas1b"
                     /locus_tag="PC494_000154"
     CDS             complement(66263..67243)
                     /gene="cas1b"
                     /locus_tag="PC494_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-B CRISPR-associated endonuclease Cas1"
                     /protein_id="HDF3910688.1"
                     /translation="MYKDYYIISNGDIKRKENTIYYYNLEGEKKILPVEQVDDIHIYG
                     EVDLNTKLINYISKYGVMLHFYNYYGYYSGTYYPRKKNVSGFSLVCQSACYLDKNERL
                     YLAKSFVESASYHILRNMRYYKVDESLIDTIKDELNDLNDVKEISELMGKEGRIRKTY
                     YKSFNQILKDDFEFYKREKRPPKDPVNALMSFGNSIMYTNVLSEIYKTQLDPTISFLH
                     EPSTKRFSLSLDIAEIFKPIIVDTIIFSLINNKRINKNDFEYQDKICYLSEKGKKKFL
                     QEFENKMQTTIKHRNLNRKVSYRMFIRLECYKLIKHFINDERYKVLKVWW"
     gene            complement(67246..67797)
                     /gene="cas4"
                     /locus_tag="PC494_000155"
     CDS             complement(67246..67797)
                     /gene="cas4"
                     /locus_tag="PC494_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated protein Cas4"
                     /protein_id="HDF3910689.1"
                     /translation="MWLKFTKEGDFVPIDLEVLKVQGVKINYYYVCKRKLWLFSKGIT
                     MEQNSSRVLSGKIVHEDSYKRMKNKEILIDDILKLDIIKDEYVKEVKISSKMKEADEM
                     QLYYYLYYLKNSMGIEKKGTINYVKEKKQEELILTEEKERIIENTLININEINMQLSP
                     SKIEKKHYCTKCAYYEFCFVKEE"
     gene            complement(67812..70133)
                     /locus_tag="PC494_000156"
     CDS             complement(67812..70133)
                     /locus_tag="PC494_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated helicase/endonuclease Cas3"
                     /protein_id="HDF3910690.1"
                     /translation="MLYAKSNPVETLREHTDELLKQMNVLRESYGKNINSLDFLEEEI
                     FWQLLDLVIEFHDIGKAFSPFQELIKSRMDTKINEPKIVTHLENNVGHNYLSPAFIDY
                     SYIDRKKNKELRAVLNQVIVYHHERDIFIDKDFKNLIQKILDEDLINKVYELQHEFKV
                     RYPIKTERLSKVYLQSVEKRIDKNHKYYNLYIMLKGILHRLDHSASAHEVVECNNVIN
                     IGEQTENYLMKEFGSLREAQSFAKSNRNKNIILIASTGMGKTETALIWIDKDKAFFTL
                     PLRVSINALFDRAKNIVGVGESNDTFLGLLHSTAIDYLEESNQENSSEIVDLAKLLSC
                     KLTFSTIDQIFKFPFLYRGYEKVYSTLAYSKVVIDEIQAYSPEIAAVLVKGIEMIHKI
                     GGRFMIMTATMPTIYIDELKKRGVMNSNLAELTCNTEKIRHCVSIVENSIDENLGKII
                     QSGMNKKVLVIVNTVKSAVEKYELIEEIVKPKGIDVNLNLLHSMYIQEDRAKLEKYIK
                     EFANSDRNGIWITTQLVEASLDIDFDELHTENSTLDSLFQRFGRCYRSREYEENSPNI
                     FIYTEKATGIGSIYDKDIVEKGLELLKTFINGKECVKMKEKYKVEMVKILYSKESLEG
                     TAFEKRFTSALNILDTITPYSLGSKDAQNILRNIEGYTVIPEDIYNKIEETLIKDYEE
                     LGQELINAYSNDDRQLINKIKSKRKKARREIIKKTVNLPIYKAKQNVIDIQVKGLEDL
                     KILLYKYDIYENKHTKQIFGKGVLISNEIDQFI"
     gene            complement(70144..70845)
                     /gene="cas5b"
                     /locus_tag="PC494_000157"
     CDS             complement(70144..70845)
                     /gene="cas5b"
                     /locus_tag="PC494_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-B CRISPR-associated protein Cas5"
                     /protein_id="HDF3910691.1"
                     /translation="MKVLKLDLFQETACYKKPFAMKITETYPLPPYSTINGLIHKILN
                     ATEYIPFNISVQGTYESIFNNYQTTYFYKKDSITSMPMNSHMLLNVNLIIHIGGDFDL
                     LEEIYDSLLNYDEHLSLGRKEDLVRINDIRFVEVNKFEVDEDIQLDDYENYKLSECNI
                     RMPIYIPKTSLQDTDIDGISYRLNNYYDNNAVEDKKRVWNKVDSYYVEDGNTISIGDI
                     LLDNEGDLLYFNNIN"
     gene            complement(70847..71761)
                     /gene="cas7i"
                     /locus_tag="PC494_000158"
     CDS             complement(70847..71761)
                     /gene="cas7i"
                     /locus_tag="PC494_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-B CRISPR-associated protein
                     Cas7/Cst2/DevR"
                     /protein_id="HDF3910692.1"
                     /translation="MKRGLTFTVIAQAQSLNYGEGIGNISELKKLSRDDGNIYTFASR
                     QCLRYDIVRLAAELFNWNLQVVDKEKGTIQFKDNISIRESEEMDLFGYMKTNKKDEKD
                     KKGGSLTREATVRLSNAISLEPYRSDMDFLNNKGFADRIGEHPNLANIEQHLSYYTYT
                     VTIDLSKIGKDGEIELDNKEKCRRVVEFLEIIKVLNRNIRGRQENLSPLFVVGGVYEI
                     ANPFFLGRIKLKGDKNGFKINKQAIEEVIQGTFLGKDLKEFTYVGMVDGVFINKEEFK
                     GLFEDNFFSVDKFFGQLVKEVKEYYGVN"
     gene            complement(71763..73640)
                     /gene="cas8a1"
                     /locus_tag="PC494_000159"
     CDS             complement(71763..73640)
                     /gene="cas8a1"
                     /locus_tag="PC494_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-B CRISPR-associated protein Cas8b1/Cst1"
                     /protein_id="HDF3910693.1"
                     /translation="MKLRVYRGDWFFNMGIVGFLNIIKKADKQAEIFIMEDYIEFDSL
                     FLENFHEYYFNYFMDEYDVSKRIKKNIDYSINFIKSKPDRIKDGIKKIKDSVKQQNDK
                     IKKFDEEKFNLIKEKLDSMSKIKSYDEFDSLEALVDETIDIFKIKSINDRLTANLYKY
                     VVQDNYFGQVSFFNVAKAKLDLDGLKQVMFNDYLRQIIYFGELEDLLEENDYDKLKNY
                     LNDRLNSIAKDINEKKVSKSSINTIEKIMKEINKNFIKKNKSIEDIKKYMDSLEVCEM
                     CGLYKGILDEYSESNFAPLGVSTNNARNMFWNQAYVPSICDICKLILFCTPAGATYTR
                     KNYLINEENEFYLFVNMDTCINELFERNNSLKAQKSEYSDSKEENPFNQLIKSIVEEN
                     TLKSEWQLRNILFVEFKASIDSKKCKINYFNIPTYLAKFFTDKYANKKIQSIYDYKLK
                     SNVLDLLLKNRDLKHLINNILRNKVKNDMESNNKSNISGIDCFRVVQLRALINSYKKG
                     VYKMDSKNLEKNDEKLRIIYYLGCDIHDYFVNKNSKNKIGGVSYKLLNSVKVGNKSDF
                     MDTIIRVFMSAEKQMPAFILDIEIEKDLDFESIGHAFISGLISGKYEGKDKLPNEKEE
                     K"
     gene            complement(73646..74383)
                     /gene="cas6"
                     /locus_tag="PC494_000160"
     CDS             complement(73646..74383)
                     /gene="cas6"
                     /locus_tag="PC494_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated endoribonuclease Cas6"
                     /protein_id="HDF3910694.1"
                     /translation="MKMKIEFSTGCIPISYNSLFMSIIKEAIRKSNEDYYKNMYYYKE
                     KNNKKTKNFTFSVYIKKYSIEGDNFIIEDKVILNISTPDLELGFHIYNGLMTSKKCLY
                     KDYELTRIRIDLSREKKVTEERVLFNALSPICVKSKEGKFLEITDDRYIEELNYITNE
                     VVKNYRGNGLKRKLEFENIGLKKVVVKESLREFKKITGKEYQYINGYKGKFILKGDID
                     DLNLIYNLGIGFRRAQGFGDVDILEWR"
     gene            complement(74461..75378)
                     /locus_tag="PC494_000161"
     CDS             complement(74461..75378)
                     /locus_tag="PC494_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WYL domain-containing protein"
                     /protein_id="HDF3910695.1"
                     /translation="MMILIQSRGKMKCKELSEELEVSERQIKSYKMYLEQAGIFINST
                     PGIYGGYEIDKCNSISLIKLLDSEVSILDMINSQLEYNNDIYKNEFNNIVEKIKAVLN
                     TGEKSDTYMDYFTVQAQCNCDYESEKNKCNEIIRAYTTKHKFWIEYYSLNSGNSERIV
                     HPYGLFNYKSDTYMVAFCEKRFKFIDFKLCRIKDYKVLEEKYNVDKSFSWDEYSKNSI
                     GIYKGEEISVVIKISHPFSTIIKEKVWVNNQQIIEYDDKSIMFKAKMRGYEEIKSWIL
                     SMGAYVEVVEPDRLRNDILLEIEKMKKIY"
     gene            complement(75657..77573)
                     /locus_tag="PC494_000162"
     CDS             complement(75657..77573)
                     /locus_tag="PC494_000162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF3910696.1"
                     /translation="MNIKQFAINNISRNIKAYLGYLASIVISSSLLFSFIMFTSHPDL
                     DVSQFPDYLKEGLKMSKIIAYLFLFFFVFYSVSVFLKSRYKEFGILYITGISKRQVMK
                     LIFIENMIINIVSSVIGIIIGLIFAKIFLVVMSTFLELSPLKFYIPFNAILSTLIYFM
                     ILAVLTSIFTSFIVKENQVLKLLKGTKTPKPEPKTSLMLAILSICLFIIAYYNAITST
                     DQYTTYLRLVPVTSLTIVATYLFFSQFSVFFMKKLKLNKRFYRKNTNMLWISNLIYKV
                     KDNARIFFLITITSAVAFTAIGTVYSFWKDVERQINLIYPNTIYYSTMTLHNDPKKPD
                     SKEKDKERMMFIENNLKKENVDYTRTNGEFKTVFPKKSDFNVRIMKESKYLEITETIG
                     VKPISFEDNECISLLSSSLPGNKNIKENIIVGNRGLKVAKQVEECVMPAYYKNMYVVK
                     DNFYDSIESKFIVDRFTAFEVEDSSKTIEICRKFENKFNNESGMQPYLFFSKELMIGT
                     GKLMYSTFIFLAIFIGLIFFVTTSSFLYNKFYMDCQVDKKKYEQLNKLGMTYNEIKKA
                     STIEIGIVFLFPYVVAVIHSIFALTALKNSFDIEVASSAVLVMGSLFLVQIVYFLIVR
                     NNYLKEIRLNLVNF"
     gene            complement(77573..78319)
                     /locus_tag="PC494_000163"
     CDS             complement(77573..78319)
                     /locus_tag="PC494_000163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001637630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF3910697.1"
                     /translation="MKILTVNNLSKVYGKKIIFNALNDINFSIEDGEFVGIMGPSGSG
                     KTTLLNMISTIDKPTTGTMELKGKNPLLLRGEELALFRRRELGFVFQDFNLLDTLTIG
                     ENIVLPLTLDKVSVKEQDERLNEVSTILGIKDLLGKRTFEVSGGQAQRTAIARALINN
                     PSILLADEPTGNLDSKSSKVVMELFQKINKENKVTTMMVTHDPLAASYCSRILFIKDG
                     SIYNEIYKGSSREQFYQEIMDVLTLLGGDN"
     gene            complement(78423..79274)
                     /locus_tag="PC494_000164"
     CDS             complement(78423..79274)
                     /locus_tag="PC494_000164"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HDF3910698.1"
                     /translation="MSLDVIFILKSVIIAIVEGLTEFIPVSSTGHMILVGNLIDFKGQ
                     FAEMFEVVIQLGAILAVVVLYWKKIKDSVIEFFKFIFTGGKEGKIGFRFGMNVIIGCI
                     PFAIIGVLFYDNIKSLFNLQSVIIGFIVGGILLLVVETLFRKKNHSTDNIDKITPIQA
                     LKVGTLQVLSAWPGMSRSASTIMGGWIAGLNSPTAAEFSFFLAVPAMVASSGKDLFEF
                     DYSIMTPTLWIALVVGFIVAFIVSIIVMEKFVNFLKKKPMRVFAVYRIIMGVVLAVLA
                     FTNIISV"
     gene            complement(79522..80526)
                     /locus_tag="PC494_000165"
     CDS             complement(79522..80526)
                     /locus_tag="PC494_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF3910699.1"
                     /translation="MKLFLKDYKGYIFIYYIGIVMTIIYCNLMKFISFGESLYILLFS
                     SFILLCFLIYKYYKNREVYNLFEKGVHSLEESFLYLGSSFLGRNISVILKQQHKLYQS
                     MIQEHKKIHSEHLTFINQWIHQMKTPISVISLQLQDYEGEEVTENIRKEIDRLNKGLD
                     MAMHFARADNFQKDFIVEKAKLNEIVSSIVNEEKRLFIKSGMIPKIQVDKFTYVYTDV
                     KWMKFIIGQLITNGVKYSKDYSNYLTIKSEENNKYVILSIIDEGIGIVSKDLKRVFDP
                     FFTGENGRKFGESTGMGLYLVKKVCDDLGHKVSIKSEVGKGTEVSIYFNKDVNSLIKV
                     "
     gene            complement(80536..81228)
                     /locus_tag="PC494_000166"
     CDS             complement(80536..81228)
                     /locus_tag="PC494_000166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011987369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF3910700.1"
                     /translation="MSYKVYIVEDDISISTLLKDYIEKYGFEVIVEENFDDIMITFES
                     FKPHLVLLDVNLPKFDGFYWCRCIRQQSNLPIIFISARDGNVDQIRALESGADDYITK
                     PFYYDVVMAKIKSHIRRVYGEYSPKIDERIVELDGLKFYPERLELELNGENLIITKKE
                     GILIECLIKRYPKVVSRDYLLEKIWDDIEFVEENTLNVNVSRIRKRFEELGIDNAVQT
                     VRGLGYKLNKNW"
     gene            complement(81542..82501)
                     /locus_tag="PC494_000167"
     CDS             complement(81542..82501)
                     /locus_tag="PC494_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NrtA/SsuA/CpmA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HDF3910701.1"
                     /translation="MKLKKLLIGITILTLATASLAGCAKKNNGEKLSEINLTYVKSPL
                     NVPSIIQKQDDLFGKEFKKDNIKVNFHEITTGPEQTQALAAGEIDFLHALGGTSALIA
                     ASNGVELKILNTYSRSPKGFMILTNNNSIKSAADLVGKKVAGPKGTILHQVLISALDK
                     EGLSMDDVEFVNMGIPEASAALSDGSVDAALIAGPAALKAMKSGSKLVANGEGLVDGI
                     IVTAVSTDFAEKHPEIVERFMKVEKETLEYVNNNFDEAMEKVAKEVDLSLEETKELYA
                     WYDFSLDITDKDISSLEDTQDFLIKNKLQEKKVNIKELIYNAK"
     gene            complement(82534..83412)
                     /locus_tag="PC494_000168"
     CDS             complement(82534..83412)
                     /locus_tag="PC494_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF3910702.1"
                     /translation="MNNLVCDSGYIIRNLYKSYKVDNEEHVVLSDISLNIDRNHITVI
                     LGESGCGKTTLLRAIASLEGINSGEIRFINDNKEYRPNVGFVFQESRLMPWLNVSENI
                     AFHNQRKNTILNKVLRKFKHNKRISSKIINDNFRSLETNDNLNKSNKYNRKSNIDVEK
                     YLKMMNLQKFKNSYPNELSGGMAQRVSIARALSFNPDMLLMDEPFSALDYFTRIDMQN
                     EVIRIHKSTNKGVIFVTHDIDEALKIGKKIVVFTDERKIKEFNIEDGYNRDLTSDYYI
                     KLKKDILMTMKSNKGI"
     gene            complement(83405..84187)
                     /locus_tag="PC494_000169"
     CDS             complement(83405..84187)
                     /locus_tag="PC494_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF3910703.1"
                     /translation="MVNKFNNKFLRLVKSVLIFFIILLLWKITNYLGIWSDYILPSPE
                     KVYSTFLNMISDGSIFINVYASMKRVLIGFAISTAIGVPLGIFFGIYSGVYEYFKSLI
                     NFLRNTPPLALIPMLILWFGIGEESKIIIIVLASFFPIFTSTLKGIKNCDSKLIEVGR
                     VFEFSKLQIIFKIIIPNAILDIAVGLKLALGYSFRAIIGAELVAASSGLGYLISDGKE
                     MSRTDVVIVGIIVIGLLGIITDYIFSIIVKKVSKGKMVEAYE"
     gene            complement(84188..84817)
                     /locus_tag="PC494_000170"
     CDS             complement(84188..84817)
                     /locus_tag="PC494_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3910704.1"
                     /translation="MNKYLLINPVAERMYGEKFHLIKANLIKKGYIIAECEPQLEYVK
                     KQYKEYTKKTKNTMLDCRCPESISLLKRNNLINDFEVPMIEPILVRTCRVLYDKYIKS
                     KDDMLVVTCPCTQLRDFASEKFKDKGNAMFYTWKEFAEQEGVKSLGKIDESPIPLGYF
                     KDTFEKVLEVSSEDEILSEIQKIRNGFEDKYDIVEMFYCKDGCNNGDGL"
     gene            complement(85212..85838)
                     /locus_tag="PC494_000171"
     CDS             complement(85212..85838)
                     /locus_tag="PC494_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HDF3910705.1"
                     /translation="MKYEWRKRDKELYLPKKNPVIVEIPEQKFIMLKGSGDPNSKEFT
                     EAIGVLYSLAYAIKTMPKKGIVPEGYFDYTVFPLEGIWDKGEKSKGLDVLIKEDLIYT
                     IMIRQPDFVTQDLLDKATDIVKKKKPHNLLEKVRFGSINEGLCVQKLHIGSYDNEPES
                     FDIMNEFCKENKLIRKSYTHREIYISDARKVSPESLKTVLRFEVEREV"
     gene            complement(85914..86885)
                     /gene="nrdF"
                     /locus_tag="PC494_000172"
     CDS             complement(85914..86885)
                     /gene="nrdF"
                     /locus_tag="PC494_000172"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HDF3910706.1"
                     /translation="MTFNLHKIHNAVNWNREEDGFTQAFWEQNVKQFWLPEEISVSKD
                     IKVWNELSNKEKELYKKVLGGLTLLDTKQGNNGIPSMMSLTENLQRKAVLSFMGTMEE
                     IHAKSYSSIFMTLLSNLEIDELFEWIETEPTLQRKADLVLAQYENTTNQEGLYLSMVT
                     SVFLESFLFYSGFFYPLYLSGQGKMVASGEIISLILRDESLHGKYIGLLAQEIYDSFD
                     KMDKEMLEEKMYSILYSLMENEIEYTNVIYRESGLEKEVVNFLKYNANRALENLGFEK
                     LYTVDAINPIVLNGLSTETKTHDFFSTKGNGYQKGVYEELEDEDFII"
     gene            complement(86898..88997)
                     /gene="nrdE"
                     /locus_tag="PC494_000173"
     CDS             complement(86898..88997)
                     /gene="nrdE"
                     /locus_tag="PC494_000173"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HDF3910707.1"
                     /translation="MNWIELNNQVIIKNEQGKYQLEKDKEALSSYIEEFIQPKLKKFN
                     NLEERLKYLIDEGYYSKEVINQYSIDVIKNIYDMIDKHKFEFQSYMSANKFYQNYALK
                     SNDGKEILETYNDKVLIVALTLGNGNKDLALNLADKIVKQEFQPATPTFLNAGRKRAG
                     EMVSCFLLSVEDSTEGISYAISSSNHLSKIGGGVALNLSKLRASGESIKDIEGAAGGV
                     VGVAKMLEQSFSYFNQMGARQGSGAVYLTVFHPDFELLMDTKKINADEKIRLATLSLG
                     AIIPDKFMELAEKNEVAYAFYPHTVYKKYGVSLDEIEMDEWYDKLVNDSDIRKKEINP
                     RQMLTKIAQMQQESGYPYVVYIDTANREHTLKDVGIIKMSNLCCEIFQYQTPSEIEGY
                     GGKNEWGQDISCNLGSLNIANVMDNKTIESTVETAIRALSFVADSTDIKPVPTVSNSN
                     SKSHSIGLGAMNLHGYLVRENILYTSDDAIDFSNVFFAMVRYYSIKASMKIAIERNQT
                     FEGFDKSEYVKGRNSKVLSKYYEQSYLPKSEKVRALFEGIYIPTKEDWTKLLDEVKEK
                     GIYNAYLMAVAPTQSISYVQNATSSIMPITEPVEVRTYGDSTTIYPMPFLTNDNMLYY
                     QSAYRMDMRKVIDLVATVQNHVDQGISTTLFVTDEKTTRDIARHYIYAYKKGLKSLYY
                     TRTKMTRDTHECLVCSV"
     gene            89475..90200
                     /locus_tag="PC494_000174"
     CDS             89475..90200
                     /locus_tag="PC494_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HDF3910708.1"
                     /translation="MKTISKQELEKTLEKHYLWLKNNNAGEKADLKELRLENMDLRGY
                     CLSNIDFSWSDLINLNLEKADLENSIFNNSYLSDCSLKNSILKNADLSGASFRFCDLS
                     NSDIRGANLENSNLEHATLNGVISDESTRFFKLYCPETGAFIGYKKCFNFRMVQLLIP
                     SDAKRVSATSNACRCDKAKVLSITSIDGKESFKSARAYADENFIYRVGETIVAEDFNE
                     NRWKESTTGIHFFLTREEAIGYL"
     gene            complement(90328..91524)
                     /locus_tag="PC494_000175"
     CDS             complement(90328..91524)
                     /locus_tag="PC494_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF3910709.1"
                     /translation="MLKTNNLSVGYNNKVVISNINVEVKNGEILCLLGSNGAGKTTLL
                     RSLSKLISPIKGEIYLNGVNINCISRKALSKKMALVLTNRLLGDLMTVQDIVNIGRYP
                     YTGFFGSLSKKDLIMVDEALESVDALHLKKRYFDELSDGEKQKVLVARALVQEPEIII
                     LDEPTTHLDIKHRLELINILKKLSKEKSISVILSLHEIDIALKSCDKVALIKNNKVIA
                     YGQPEDVVDEDIINSLYELDDKNFNSLLGSVEISNKSKNEVFIIGGGGKATPIYRAFT
                     KKGIGLYSGIIHENDIDYEIGRTMGIKMFTENPFEPISDESFDLAIRNLNDSKIIIDT
                     GFSVGETNKRNIDIIKEALKLDKKVYSFRNRDESKKYYDSLDNKIEHIDKVSQIINSA
                     DINNLL"
     gene            complement(91527..92552)
                     /locus_tag="PC494_000176"
     CDS             complement(91527..92552)
                     /locus_tag="PC494_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HDF3910710.1"
                     /translation="MDFINKMRIRNTTIFIVLIISMILTFLVCVAFGSVKIEFKEVID
                     VVLRGMDNTEHYKIIYNIRIPRVLATMVGGACLAVSGILLQIFFKNPIVEPYILGVSS
                     GSTLSVALMILGGYTLGFESVNSMSIFVAAFIGALIVMSIVILFANKVKNITTLLIIG
                     IMTGYVCSGITNVLQSFANSDKLKEFTMWSMGSFSGFTWEKVEILIIVGILGLLMTVF
                     IIKPLNAFLLGEEYAKSIGINIRFFRVLIVFISSILAAIVSAFAGPIGFIGLAVPQIS
                     KLIFKTSDNRVLIPVVIFLGSIVTALCDLISRVILSPVELPISTITSLLGAPIVVMLL
                     VKRKDRA"
     gene            complement(92624..93754)
                     /locus_tag="PC494_000177"
     CDS             complement(92624..93754)
                     /locus_tag="PC494_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDF3910711.1"
                     /translation="MKFKSNVLKQFFLIAMVIFMVGGLIGCSKSDKENKQASTGKKLE
                     LKYASGFSVEDLEDGIKKVTDGDNRELILIPKKIKIPEKYKNANIVRTPVDNVLIAST
                     TQACSLRTIDELDSIKAVTTEEQYWTIKEIKDLMKDGKIHYVGSNLAPDYEKIVDLNP
                     DLTIVSSGLSEADTKFIDKLKELGLNYVVDNEYKEQNPFGRMEWTSLIAAFYDKEDMA
                     TSELNKTVQKVEEVSKKIKNKAKPKVVWASVYEGSAYIAPKDSYVDNMIKMAGGINAC
                     ASIDSNEGRVSIEQLHEVAKDADIFVYSSSSDYAPNLDSIKSSAPVLADLDVVKNGNL
                     WVFAPDYYQSVDKTDELIVDLVEMFHPGTTGEKIKHYINYDK"
     gene            complement(94348..94743)
                     /gene="tnpA"
                     /locus_tag="PC494_000178"
     CDS             complement(94348..94743)
                     /gene="tnpA"
                     /locus_tag="PC494_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
                     /protein_id="HDF3910712.1"
                     /translation="MKLDSNNHSVFLLHYHLVMCIKYRRKVIDDSISDRLKDIFVDIA
                     PNYGVVLIEWNHYVDHVHLLFKAKPNTEISKLLNAYKSASSRRIKNEFPSIRKYLWKE
                     YFWSKSYCLVTTGGATLEDLEQYIENQEE"
     gene            complement(94908..95915)
                     /locus_tag="PC494_000179"
     CDS             complement(94908..95915)
                     /locus_tag="PC494_000179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003358391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HDF3910713.1"
                     /translation="MRLREYIGDKVVFLGTNLIIFLIASGIMLYSKINVVLIFMLFCI
                     WFLPLFTYMLIDYLQYKKYFNSIDNILDALDKKYLLPEVIDDVNFVTGEKINDILKVI
                     SRNMHENIKYYNDNQEEYKEYIETWVHEIKTPIASSKLIIENNSNEITKKIDTQLDKV
                     ENFVEQVLYYSKIDNVNKDYIIKKLNLEEVVNEVIKRNYRDFINKNIKLELGEINKTV
                     YSDSKWVEFILNQIVVNSIKYIKSKDGLIKISAKRVENSIVLTIEDNGVGIEERDINK
                     VFEKGFTGENGRVFGKSTGIGLYLCKKLCNKLGLGLILESKVNVGTVIKVSFPIDYNL
                     F"
     gene            complement(95912..96583)
                     /locus_tag="PC494_000180"
     CDS             complement(95912..96583)
                     /locus_tag="PC494_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005210744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF3910714.1"
                     /translation="MEKIIIVEDEEVIRDELKSFLERYGYEVMAPTEFDNIVEFILSE
                     KPNLVLLDINLPIYDGYYICRVLRKESNIPIIIVTSRNTDMDELMSMNLGADDFVTKP
                     YKTQILLARIVALLKRSGLNSNVNNTLIFKGIELNLFNATLRYKDKEIELTKNEFKIL
                     SYLVENQGSIVSRDSFMEYLWHTNWFVDDRTLTVNITRLRKKLDEIGIENLIETRRGL
                     GYIIS"
     gene            complement(96660..98654)
                     /locus_tag="PC494_000181"
     CDS             complement(96660..98654)
                     /locus_tag="PC494_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003400181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF3910715.1"
                     /translation="MYSKIAIKNVRKSFKDYSIYFLTLTLAICIFYSFNSIESQKALM
                     EMNASTKSHVEMLKNMISYMSVFVSVILCSLILYANNFLVKKRNKELGIYMTLGMEKV
                     KISKILVFETIIVGIVSLVSGLILGLLVSQGLSILLLKLFEFNMSEYNFVISISSIIK
                     TIVYFGIMFLLVMIFNTYIISKYKIIDLLTIGRKTEDIKFKSPFVYTITFILCIISLI
                     IAYSMVLKVGLNPKNPKFIMSIVLGVIGTILFFYSLAGFALYIVKKNKNIYFKGLNIF
                     VVKQINSKINTNFISISIICLMLFLTIGILSTGFGFKSALNAGLKGATPFDASATMIV
                     HEKCKVKNIKESFEKVGIKFNKGDKVAYYDEYINGNKLSDVMQGQYSGRVDFEVAYIK
                     SSQYNEIRKLRGEKSITLSKDEVLITSNATEVVPSIEEYMKNNKIIKIDNKAYNIKNK
                     KVIKDNLRTDFTETNALTVVVNDKLCDSMEISSSIVNINFASDNNEKSQENFDKRLKS
                     KYSSTSFYEVGTVSGGSRNAMYNDNNGMTSTILFVGIYLGIVFLISSMAVLALQQLSE
                     ASDSIDRYVSLKKLGASKNSISKTIFTQTLMYFSIPVGLALVHSVVGIQVANNFISRL
                     NKPDIGASSLMTVGILMLVYAVYFYTTYQGYKNIVIKKLN"
     gene            complement(98644..99411)
                     /locus_tag="PC494_000182"
     CDS             complement(98644..99411)
                     /locus_tag="PC494_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014521021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF3910716.1"
                     /translation="MKNILSVEKIEKYYGNKDNITKAIDNISFKVDEGEFVGIMGPSG
                     SGKTTLLNCISTIDNVTIGKIIINNNDITRLKSKNLDKFRQNELGFIFQDFNLLDTLT
                     AYENIALALTIKGEKPSKIDSKIRDVATYLEIEKVIDKYPYQMSGGQKQRVASARAIV
                     TNPSLILADEPTGALDSKSARLLLERFESLNQDLKATILMVTHDAFTASYAHRILFIK
                     DGKIFTELVRGADSRKEFFNRIIEVTTLIGGDDNDVF"
     gene            complement(99666..100511)
                     /locus_tag="PC494_000183"
     CDS             complement(99666..100511)
                     /locus_tag="PC494_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003485307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF3910717.1"
                     /translation="MYSKIAIKNVRKSFKDYSIYFLTLTLVICIFYSFNSMESQKALM
                     EMSTSKKPDLEMFKNMISYISVFVSAILCTLILYINNLLIKKRNKKLGIYMTLGMGKI
                     EMSKILVFETIIVGIVSLVSGLILGLLVSQGLLILLLKLFEFNMSEYSFVISIPAIIK
                     TIVYFGIIFLLVMIFNIYLISKYKMIDLLIVERKTEDIKFKNPFVYMITFVSCFIFLF
                     TVYNTTNHIIINLIDDKQLNSKSKGVEINEFTYQDWQQFCDIKYYGKKGLISMTLKEY
                     IEKYK"
     gene            complement(100501..100974)
                     /locus_tag="PC494_000184"
                     /pseudo
     CDS             complement(100501..100974)
                     /locus_tag="PC494_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014521021.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(101680..102573)
                     /locus_tag="PC494_000185"
     CDS             complement(101680..102573)
                     /locus_tag="PC494_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="HDF3910718.1"
                     /translation="MKAEFLTPVVTIFDEEGNLDKEGNKKVYDHLIDGGVDGLVIMGS
                     TGEFFNMSMDMQKELIDLVTSHVNKRVKVFIGTSRMCINESIELSNYAHNSGADGVMI
                     ISPYYFSLDDDSIELFYSEIAKNTEAEIYLYNYPDRTGYDLSPELTLRLARKHKNIVG
                     YKDTVTLMGHTRDLINTMKIEFPEFKVYSGYDENFIHNLMSGGAGCIGGLSNLIPEVC
                     SKWAEAYNNRDMEKVIEIQKYINKAMDFYLITNPFIPAMKKAMNIRGLQISDYMTAPF
                     VKPNEKQVCEIKKLMNELNIC"
     gene            complement(102653..103555)
                     /locus_tag="PC494_000186"
     CDS             complement(102653..103555)
                     /locus_tag="PC494_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fumarylacetoacetate hydrolase family protein"
                     /protein_id="HDF3910719.1"
                     /translation="MKFVSFTEGENECKRTGVFSKDELFIIDVNSLNLSRNFKDLNEL
                     IQNVSSEDIIKLKTIINESTFYNYDVFKRERCTVHVPIEKPIHDILCVGVNYKDHLEE
                     TQTHFDDSFEEPQKTVYFTKRVTKAIGPEDEIDGHFEINNQLDYEVELGVVIGKTGVN
                     IRKEEVEDYIFGYTVINDISARKLQKEHVQWFRGKGLDTFTSLGPCILHKSAVPFPIK
                     LKVCSRVNGEERQSSNTGLFISDVSDIVSELSKGMTLEAGDIIATGTPSGVGMGFSPP
                     RYMSSGDVVECEIESIGILKNYIK"
     gene            complement(103605..104765)
                     /locus_tag="PC494_000187"
     CDS             complement(103605..104765)
                     /locus_tag="PC494_000187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UxaA family hydrolase"
                     /protein_id="HDF3910720.1"
                     /translation="MKFYGYKRPDGRVGIRNHILILPTSVCASDTTRIIASQVQGAVT
                     FNNQNGCSQVHSDQQLTMDVMAGYAANPNVYGVIVVSLGCENCQNDLVVDAIKERTNK
                     PIKTLVIQEEHGTLKTIEKAVRYAREMAQEASLLRKEEFPISELILGTECGGSDPTSG
                     LAANPLIGELSDKLVDLGATSILSETTEFIGAEHILARRAVNEEVKEKILHIVHRYEN
                     SLKLVGEEVREGNPSPGNIAGGLTSLEEKSLGCIHKGGHRQISEVYDYAKQIDKKGLV
                     IMDTPGNDASSVAGMVAGGAQIVVFSTGRGTPSGNPIAPVIKITGNKITFANMEDNMD
                     FDASPVIYGPQTMEELTDDLLNMVVDVANGKQSKAESLGYTEMAIARVCNYV"
     gene            complement(104921..105226)
                     /locus_tag="PC494_000188"
     CDS             complement(104921..105226)
                     /locus_tag="PC494_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UxaA family hydrolase"
                     /protein_id="HDF3910721.1"
                     /translation="MINAVIIDEKDNVAVAIEAIAKGSEISFKLKDKTVKTITALDDI
                     TIYHKLAIKDMAKGDKVTKYGEHIGEANQEIKSGQHVHIHNVRSVREDLDKQVMTNI"
     gene            complement(105324..106298)
                     /locus_tag="PC494_000189"
     CDS             complement(105324..106298)
                     /locus_tag="PC494_000189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-keto-3-deoxygluconate permease"
                     /protein_id="HDF3910722.1"
                     /translation="MIMDFIKKIPAGMMIVPMFIAAFINTFCPDIVQIGSFTTAVFSS
                     VGSATIIGVQLVCLGTQLQFREMPKVLKRGGILLGSKFAIGALIGILIGKLFGMDGVL
                     GLTTLAVISAVTNSNGSIYLSLMTSYGDETDCATMSLLTLNDGPFFTLIALGTSGLAN
                     VPLLSLLAAIVPILVGMIIGNFDKKMKEFLEPGCNLLVPFVGFALGSSINLASILKGG
                     LSGVLLGLISVFVGGIFIVFCDKFIGKRPGYAGWAVATTAGNAIAVPAAVALVDPSWQ
                     PYVATATTQVAAAVVVTAILVPLITSWWAKKYGCPKFPKQNEDGTITA"
     gene            106880..107656
                     /locus_tag="PC494_000190"
     CDS             106880..107656
                     /locus_tag="PC494_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IclR family transcriptional regulator"
                     /protein_id="HDF3910723.1"
                     /translation="MTSDNHRPTARILDILEALAESENGYTLTEIADVINAPKSSIFP
                     IVHTLNARKYITIDKNTSKYSIGIRSYTLGSSFFEKRTIFNYIIDEMTNIVNSCSETC
                     QLGILDNNEVLYIGKVDSPEPIRLISYVGKKIPANCTGLGKALLCDFDKEKLISLYPD
                     GLKGFTEKSITDFDVLYDQLLEVQRTQIASECEESMEHLKCLAVPIRKNGCIRAAVSV
                     TLPLFRANDEKIELIKKLLLNAQKNIQSMMEERNEDIVIN"
     gene            107988..109133
                     /locus_tag="PC494_000191"
     CDS             107988..109133
                     /locus_tag="PC494_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HDF3910724.1"
                     /translation="MSIYYVPPINLLGKGCLNEAKDSIKSLGTKKAFIVSDKFLVSNG
                     TVKKVTDILSQIDIDFVVYDEVKQNPTVTNVNKGLKILKSENCDFVITIGGGSPQDCG
                     KAISILATNGGDIRDYEGINKTSKKCLPIIAITTTAGTSAEVTINYVITDEDRHVKMI
                     MVDTNSLATMTVNDPELMISKPSNLTAATGMDALTHAIEAVVANGAYDVTDSTALYAI
                     KQIFKYLPRAVKNGNDIEAREQMCYACFLNGIAFSNAGLGNVHAMAHQLGGLYDLPHG
                     VCNAMLLPIVEEENAKSAPAKFRPIAEVIGMDVNNKSDKECVDFVIDKIKALSEEVGI
                     PKSLKDVGVDNPNFELLAENSMKDACAGANPVFFDKDKIIELFMKIS"
     gene            complement(109288..110157)
                     /locus_tag="PC494_000192"
     CDS             complement(109288..110157)
                     /locus_tag="PC494_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SH3 domain-containing protein"
                     /protein_id="HDF3910725.1"
                     /translation="MRGWICVKLTKLNIKKYRAPIYKYALANVNLRSAKSTNSSIITV
                     IPQGAKMEVLDEEDDWIKVMYNSQEGYVYKDLVSVSEYAWSNLNLREDKSTTSNIITV
                     IPEKSRVEVLQVDGDWSKVVYDDKIGYVFNYFLSIDGNKPNELDYKYFYTDMIKFVNE
                     NNIKSTSDYLIVTDLRNKYTYIFKKDNGGWGQLYKWQCTIGKPETPTITGIFYISGRK
                     PSFGTDEYSVKYATRIKGGYYYHSVLYDSTGSYIIDGRLGEALSHGCIRLSTENAKWI
                     YDNIPDTTTVIIH"
     gene            complement(110275..110988)
                     /locus_tag="PC494_000193"
     CDS             complement(110275..110988)
                     /locus_tag="PC494_000193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017208807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF434 domain-containing protein"
                     /protein_id="HDF3910726.1"
                     /translation="MNKISKRGFDDSDKRWFSSKELTRLIKAKEEIEWLLNRDYKIDP
                     VVTFVGDRYQFSIRQRDALKRAVCTDEKNIIRQSKRLSLDKIKEDTVNIDGFNLIISI
                     EVALSGGTLVIGSDGNIRDLAGLRGTYKIIDKTEEALNLIGKFFNKYNAQNLKFYLDA
                     PVSNSGNLKYRILEHAKTWGIETEVELVKNADVVLEKLDRVVSSDAVIVDKCISYFNV
                     ARGIIEEYIKECNIINLNK"
     gene            complement(111359..112747)
                     /locus_tag="PC494_000194"
     CDS             complement(111359..112747)
                     /locus_tag="PC494_000194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HDF3910727.1"
                     /translation="MKKTFDAIIIGFGKGGKTLAGDLANRGLKVALIEKSNKMYGGTC
                     VNVACIPTKSLENSANSVKTKNINSWDEVQAEYEKAIDKKETLITKLREANYNKLNSN
                     ENVTIFTGMGTFIDEKTVQVKTENEIYELVADNIFINTGSRPFIPNIKGIENKNIVYD
                     SESLMNLRTLPKKMTIIGAGFIGLEFAGIYSSFGAEVTILNSNNGILPNEDVEDSEEI
                     IKLLAKRNVKIVNNANIKEIKEVSELAIVEYEVDGKSKELTSNMILVATGRKANTEGL
                     GLENAGIELNERGFIKVSETLKTNKEHIWAIGDINGGPQFTYISLDDYRIVINQLFGD
                     KTRTTNDRKNIPNSIFISPAFSRVGLNVKQAKEKGYEVLVAKMPVEAIPRAKQIGKAD
                     GFIKIVIDKKSNKILGASMICENSSEIIHLIQLAVDLEVEYTYLRDRVYAHPTMTEAL
                     NDILSPNMIKEV"
     gene            complement(112868..114145)
                     /locus_tag="PC494_000195"
     CDS             complement(112868..114145)
                     /locus_tag="PC494_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redoxin family protein"
                     /protein_id="HDF3910728.1"
                     /translation="MQNVNLFLVFIEGIVSFFSPCILPILPIYLSILSNSSVENLKEG
                     KTSFIGSSLFKNTIFFALGISTTFFILGSSVKVLSMFFNENKDLIMFIGGIIIIIMGL
                     FYMGIIKSSILNREKRFNVKFKEMKAITAFILGFTFSFGWTPCIGPILASVLVMVSSS
                     SNHLSANLLIAVYTIGFILPFIITAMFYSKLFKTIDKIKSNMEIIKKIGGIILIVSGI
                     LMMVNGFGSISKHFNTSQNSKIESKQEENKRENSTDKEENSDGNDSQKDSNNDNNDKG
                     SNDEDRIKSIDFTLTDQYGKTHKLSDYEGKVVFLNFWATWCPPCKEEMPYIEQLYKDY
                     NKNNDDVVILGVASPNLGREGSREHVVNFLKEQGYTFPVVLDEDGALAYQYGINAFPT
                     TFIIDKERYVTQYIPGAMDKATMASFIENQRNK"
     gene            complement(114282..114617)
                     /locus_tag="PC494_000196"
     CDS             complement(114282..114617)
                     /locus_tag="PC494_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF3910729.1"
                     /translation="MYNIDDMIYNCPVEALSNILGKKWVAIIIWKIQEDKKRFGELQR
                     AIPDCSKKMLVQQLDFLIEQGIIVNQKKLVNNVVESTYFLSESGLRLLPVMEKMIMWS
                     NKNLNCDKY"
BASE COUNT        38129 a        19680 c        12658 g        44286 t
ORIGIN      
        1 taaatattaa tactataaat aaaaacgaag cataattttt atttaaataa atctcaaact
       61 tcgtctttac ttacttagat atttatttac tttctaaatc ctattatttt tagaacctta
      121 tcttttcaat acttcaccac atttattctc agtaatctct ccattttcta atgcaatttt
      181 tccatttaca attacatatt caacaccatt ggctagtaat tgtggctttg aaaaatcaat
      241 atcttctgac ctaggataac tatagttatc catgtcaata actgctatat cagctatcaa
      301 cccttcttta agaatacctc tattttttat tttaaattgc ctagctggta atgaagtaac
      361 tcttcttaca atctcttcca atctaacacc agactttctg tacatattga agaaaattgg
      421 aaaagctcct cttctttgta gttcaaacca tgacatatcc ccacccacac taaacaaaca
      481 atctgaacca accataacaa atggattatc aattatttta tcatcatgta gtttatctgg
      541 gaaatcagct ctatacattc ctcctaaaca aaagataagt tcttcgtctc catctaaaag
      601 taaatcgagt aataacttgt cttcatctat tcctttttgt gtagctattt cacgtattga
      661 tttcttttcc atattaatat ctttagtgtt tagaagtatt atactccccc tatctccaag
      721 tataaatgct tcttttaata taagtgttct tccctcttca tttctaagag catccattac
      781 cccatctata cctaattcaa atagactaga tgatattgcc ataataaatt gaattactct
      841 ttttttcttc atacaatgcc cagaacttct tggtactgtg tcaaccatta tttcaacacc
      901 attataccta gcctttaata tctcatcaaa tgcttctatt tcaactggac ttaagtgaga
      961 tacttgaacc ctagcaccac ttttttgccc aacctctatg gcttctttta ctgcattata
     1021 tcttcctatg taatctctaa tatgagatgt atatatacca tcatactctt taatctgcct
     1081 tgcaatatca acaagttcat caatatcagc atacttactt ggtatatatg ccaatccagt
     1141 agatattcca aaagcaccac ttttcattcc atcatttatt atatctgtaa tttcattttt
     1201 ttccttttct gtaggaggtc tatccttaga acctcccata acactccatc ttatagtccc
     1261 atgccccaac aagaatccca tattgacaga aataccactt ttagatataa ggtcacaata
     1321 ttctgtaaaa ttattccaac atttattttt atctataaga tacttttttt cttcttcaag
     1381 taatagacca tttttataca tatattcata cacattttca gaagaatatg gtgttataga
     1441 atgtccacaa ttaccattta tagttgttgt aactccttgt tttagaaact tttcaaattt
     1501 accatctagt attgctacta tttcttcatg aacatgaggg tcaataaatc caggtgttat
     1561 aacttttcca caacaatcaa tctctttatt tgtattgcta tttatcttag aatctatttt
     1621 tgctattaag ttgtctttaa ttgctatatc tccataaaaa ccaggattac ctgtaccatc
     1681 tattataaat ccatttttta agattaaatc atatatcaaa atattccctc cttaaaaacc
     1741 aatttttaaa taatcttaat gtaattttta tatttgaaaa tcaaattatt aaatttcata
     1801 tttgaaaatt cactattatt tcattgtaat tagtcactaa gcttatcttt atacatagct
     1861 cttgcaatta atatagtacc aaatacacat ataagaacta ctagagactg tggtattata
     1921 ccttgctttg ataatataat agtcaataca gatattacaa ttgctactag acctaatttt
     1981 ttatcttgta aaaatacttg tccaaaaact gacccaaata gagctggtaa aattaagttt
     2041 aatttttcta ctacttcagc tggaatttta gatagtacgc ttcctcctaa aattacccct
     2101 atagttagta tacttatatt cactaaaata gatacagcta ttcctattgt agatattatc
     2161 gagccttctt ctgtacctga ttcaacttct gctgcctttt gagctgctat tgaacatggt
     2221 agcctcatat tagatatatt accagaaaga aaactcatat aagttcctgg tatacctaag
     2281 attggtgaat aagaaactgg ttctattatg taatttggag cactcatact gacaattgcc
     2341 attgtacttg ctaataatgc tgatattgga ggcataatac caaatccaaa gctcaaaatt
     2401 attccaggaa ctaatgctgc tataataccc aaagatagtg ttaatcttcc ataccttatc
     2461 ataaaaggta aatattcttc attgtatata gattttactt tactcataaa actaactccc
     2521 cccttatatt actgaagcta ttatcattcc gctaaacatt gatattgtaa gcccccactc
     2581 tcttaaccat tttatatttt tcttcttttc aagcatacac aatattacca ttatagccat
     2641 tccacttata catgcaattg ttccattatc aaaacgcaac accctatcag catttagata
     2701 tgcaaatgaa cccaacattg ctcctagaga tattattggt ataaatgatt tcttgccact
     2761 agatataaca ttggttatct tatctagttt atgtccaaat agtaatgtga atattatcca
     2821 tcctaaagaa cctaatatca tagtccaaac tgcatttgta aatgcaagtt ttgtcatttc
     2881 aggagaacct aaagttatac ctaatgcatc tgttccaaat ccggctgaca ttgattcaaa
     2941 aattacagaa cctataaatg ataatctcat ccatgctata ggcccaccca tagttactat
     3001 aagcgatacc attccagcaa atatagtcat tgaaggccca atagctgaaa tagcactact
     3061 cttaacagct gactttattt gtttatctgt tattcccatt gttttaccaa ctttgcaaga
     3121 ttttatagca aatataaggg attgtaccac tactattgat actgctactg tactcgctat
     3181 ccacaaaagt ggatgattag ctaattttaa ataatccatt tataaaacct ccctataaat
     3241 cctcaaattt tattaatatt tctaatatat ctatttccaa acctgtttta gtactctaag
     3301 tatatttcca cctagtacct tctctatttc ctcatcacta tatccatgct ttactaaata
     3361 tctaacaatg ttttttgaag tttctgttgg gttctcaaga ccttttacat attctacttt
     3421 gggatgttct tttgttcctg ttattttttt tatatcaaat ttagcagcta gtactgagtg
     3481 taattttaca tggtcgccat atactgtatc tggtccaaaa gctacatggt ctattcctac
     3541 taaattttta atatactcaa aatgttccat aaatgactct attgaatgtt ctttattctt
     3601 ctctgttatt gtagtatgag gtgctgcttc tacacctata acccctcctt ttttagcaca
     3661 tgctattaat acttcatctg gagttagtct ctttgtgttc cataaatttc ttgccccaac
     3721 atggcttaat attattgggt ccttgctata ttctattaca tcaagtgtag tttgaactcc
     3781 aacgtgagag caatctattg ccattccaat tttattcatt ctttcaacag cttttttccc
     3841 aaaatttgta agacctccat ctttctcttc ttttagtcct gaacctaatg cattggattc
     3901 gctgtatgtt atacccatta accttatacc aaatccatac agtatatcta ttctatcaag
     3961 ttcattttct attggtgctg caccttctaa tgttggtatc aatgctactt taccttcact
     4021 tttagctctg tatatatctt ctactttttc acactttatg acaaaatctt gatgagctaa
     4081 atcacataat ctcatgccta aatctattaa tatatcatcc catttccacc ctgaatttga
     4141 tgttatcgta catacaccat ccattaaatt atcaaatata gcatcataat atcctcttga
     4201 taatgcttca taagcacatc tttgtttacc ttccctatta tattcaaata tatctctttc
     4261 taggtgttct ggaaataata ctggatgttc atgtaatgat ataaatattt tttcatccac
     4321 tatactttta accttagctt cttgaatatc atctaattca ataaggtatt ctttaactct
     4381 tttatctcct ttacacatct caatagatga aatatctttt cctttttcta aataactata
     4441 ggcttcatat cctttgtaag ctgacttcat aacaacatcc tccaagtttt acaatttttt
     4501 atatttttcc tatgtagcaa ttgatgtgcc aaaatataaa ttttaattgt ataataaatc
     4561 ttgcaaaaaa taaaaacagt agtaaggttg atatttacta ctgttttatt aaaaataatc
     4621 ttcttagatt atttattcaa tatttttgaa ttatcttaat cttaaagata attttattta
     4681 tttctatcca ttatagggat ttttttaggg tgttttgcct ttttagtccc ctatatcact
     4741 cccttaattt ttacatatga tataaagttc tttccttcat cagttataaa actaccttgt
     4801 ttttttactc cagataaaag taaaccatgg ctctttaact tatctattct ttttctaatt
     4861 tggtctacac ttaaaactat atctttttct tttaaaatct cttgcagttt atttcttcct
     4921 aataatatat ttttattatt ccaagtttct atactggtca atatacatat actttcctca
     4981 aagaaattag attgtttgaa atctaagata attgaatcga aattttcatt aactaaagta
     5041 ttgttttttt caaatctaaa ttgttctggc aaatgctcgt aatctactct atcttcctca
     5101 actatagtat caatataata aattaaattt ttaagctctc ttacatttcc tggccattca
     5161 tacaatgtta aagcttgcat tgattcctct gtaaaacatt tgttgctatt tatttcatct
     5221 aaaaaatact tacttataag aggtatatct tccttacgtt ctctaagtct aggtatctct
     5281 atatgtaata cattaatcct ataatacaaa tcttctctaa aggaaccttc tttaattttt
     5341 ttctttaaat ctttatttgt tgcagctata attctaacat ctattggtat aattttactt
     5401 ccgcccattc tcataacttc tttttcctgt aatactctta gcaatctctg ctgtacatct
     5461 aaagatatat cacctatctc atctaaaaaa attgttcctg tgtgtgctct ttcaaatata
     5521 cccattttcc caccttttat tgctcctgta aaacttcctt catcatagcc aaaaagttca
     5581 ctttcaataa gtgtatctga caaagaagat agattaactg caacaaatgg cttgtttttt
     5641 cttagagatt cattatgtat tgcctgggca aatatttctt ttcctgttcc attttctcca
     5701 agtatcaaca cagaaaagtc tgtagttgct atttttcttg caatattaat tttttctttt
     5761 attattttac tctcacctac aacactctca aatgtatact ttgatacaaa accttttgac
     5821 tgaagtttat tttgaatctt gtcctcaagc acttgaattg cacttatatt tttaatgctt
     5881 ataatactct ttattcgttc attattttca taaacattta ctttattaat tatcagtttt
     5941 ttgttattta aatttactac ttcatcatta acttcatctt cttgaaaaaa tatttttttg
     6001 acaaccttat cactaaataa gtccataaag ttattagata taatttcatt ttggtctatt
     6061 ccaactagat tagaaaatac tttgttgcaa tatataaatt ttcctaattt atcaacagaa
     6121 gcaatacctt catctataat ctccaaaaaa ctcttcatgg ttttattcat agttgtataa
     6181 tacctatatc cacttactgt atcttcattg tatttttcct taataatatg taatttatct
     6241 atagatatat ttagttttgt aaagatttct ataactgtat ttatatcaat taccttatca
     6301 cctatgtcaa ttatttgctt tatgttttgt ggtatgctgt ttctgcttcc tgtaataatt
     6361 ccaatctcac atttagactt atcacaacct ggataatatg gtattagatt aatatgaatt
     6421 aatcctagtt ttctaattat cttggcagtt tcatctgctg actctttata agcatctata
     6481 accataacat cagaatcatt ttctatactt attatctgat ttatattttc aatatttata
     6541 gtacgatgta ctattacaat aggtatattt ttatcaatat tattatgtat atattccttt
     6601 atatcattgt ctgaacatac tacaagctca tagcttgaca gttcaatatt tatcctattt
     6661 acatatacca agttatctat attacaaaat tctccaaata tattttccaa ttgttttgat
     6721 atatctatat ttattttgtc atcagttgat acaaataaaa tattatgttt tttcatagtc
     6781 ccacctcctg tttaacgagt atagaaagta ataatttggt ctattgtagc actttttaaa
     6841 aaagttttaa atcttaaaaa tcaaattttg taccatttac tattattttc cataataaaa
     6901 taatgtaagc tatctttttt cacatataat ttaatttcta aaacggttag tttgacatta
     6961 ttggaatata aacaaaaatt taatataaat tcgttaatat attaatacat ttttaagaat
     7021 gacaaggaat aaattataac aaattttagg aatatataat aatagggtct cagaacttag
     7081 ttacaagttc taaaacccta tttgtttagt gtaaaaaaca tcataaaatt tagcttaaat
     7141 cttttcacat aatattactc tttttctaag tgataataaa atatatctat tcctctaaaa
     7201 actgtaaaaa ttcctgatta aatagtttaa gctcatcata gaatatagca tgaccactat
     7261 actcaaaagt atataaaatt gaatcttcta ttttttcatt cataaaaact gcaaattcat
     7321 acggacatat ttcatctaat ttcccatgaa atataccagt aggcactctt acacatttta
     7381 aatcattaaa taattcttca tctcttaaag atacagcagt tccaatagtg ccaatacctg
     7441 atgcactaaa accaatatca ttaaaccatc ttctaaagct ttctggtgga tttgatgcaa
     7501 atactttttc gccaaaatcg gttaccattt ctggtctatc agtacatgct tgtgctatca
     7561 atttatttac atcttcacgt gtcataccat atggaaattc tggaggtctt tgtacaaatg
     7621 atggtgcagc agctgcagct aataccaatt ttgacactcc atatccatta aataaactca
     7681 tatacctaag tacgattgct cctcccattg aaaaaccaac aagggtaaag tcttttaatc
     7741 caatagcatg taccacctta taaatatcgt ctgctaattg gctataagta tatcctcctg
     7801 atgttgcatc agatttacca aaacctctta aatcaattga aactgttcta tatccgagtt
     7861 ttggcaatat atttgtttga tattcaaata tcttatgtcc taagggccaa ccatgtataa
     7921 aaagtacagt ttttttagca ctcggattca aatcatatac tgctatgttt atatcattca
     7981 catatacata atacatatca acagcaactc ccttcaagaa aatgtatgat ggttatttta
     8041 tatatatgaa taaaatgatg aataactaaa ttttcaaatt tatttacaat acttctctat
     8101 tgccttttca aataaactta catgaagttt ttcatctagg attattctat ttaatatagc
     8161 ttttatataa gggtcttcaa taagacttat gtctttataa taattattaa tagccacatg
     8221 ctccaaatgc aaatctagtt ttaatctgtt acaaatagaa tttccataac atacaaaacc
     8281 accattccaa tatgcaccac aagaacttgt agaacctcta tatacaggat ttccacccaa
     8341 taatcttata gtctttgcta atatctccat atgtaacatt tctgttatag atatatttat
     8401 ccacatttca cttaactctc tatgcgtttc atctaaatca aaattatggt atagatattg
     8461 atttacactc gtaaattcac ttgatactcc ggcatagtca tccatcaata attctgcata
     8521 gtacttattt ggacctaaaa cttttatctc tggatatggc tcatcacttg aatatccatt
     8581 tcgcttgtgc atgtcataat gtgcatcact cataatatct cctcctttaa atttaatgta
     8641 tgatattaat tgtatgcatc acaacttttt catataactt agataataaa atctacttaa
     8701 ataataaaaa gccatattaa ttaaaattaa catgaccttt tatccacaaa attacttttt
     8761 aattattcat cttttccagc tactgatagc tctttaataa caactgaagg tgaacctata
     8821 ctactcattg gaaattctaa atcttctcct atagcttcaa tatctttcaa caggtcaaaa
     8881 tagtttcctg ctactgtaat ttgctccact ggaaatactt tttttccttc tttgatataa
     8941 aagcctttgg cagctaaaga aaagtctcct gttactgaat ttgcacctga atgaagtcct
     9001 gcaaagctag taaccatcaa tccttcatct atatccttta taatttcatc taaagattta
     9061 tctcctttct ctatataaaa attagttgga tatatgctta taggtgatga atatgaagat
     9121 tttattccat ttcctgtagt ctttacacct gccttattag ccgtttttaa gttatgaagt
     9181 aaagttataa gctttccatt taaaacaact tcttttttaa atgtagctac tccttcatca
     9241 tcaaaaggag tagatgccat accattttct aaaagtgggt catcaactat tgtaactata
     9301 ggagatgcta tcatgtctcc ttctctattt ttcaataaag ataatccttt ttgagctgaa
     9361 tctgcattaa atatcccaga aaatgtgcta agcaaagata ccatagcttc attaagcaat
     9421 atagttttat atttacctga tggaatactc ttaccaccta ctttagataa agcattatca
     9481 acaccaagtt ttgctatctc acaaggtttt atttcttcaa tagaatttgc tatattatat
     9541 cctattccat catatttttg tccattgtct tctatgatag gaactacaaa ccctataagc
     9601 atattagttt tattgcttaa attaagacct ttagtattag atataccatt acttgataca
     9661 gaataagata tagtacattt agataaattt accaccttat ctgaataagc tttagtctct
     9721 ctttccattt ctaaagctaa atcaatcaac ttatctgcct ctaaattttc tagctcttta
     9781 gaataagtct ttacatcatt atagtgctta tctccttcat atataaattg tacatcttca
     9841 ttttcaatag tgtttactcc atcttttaca ttttttatca acatatcaac agctttatca
     9901 tctaaaattt ctgtataaga ataacctatc tttccattta ccttacctct aaaagataaa
     9961 ccaaaagatt tatcaagatt gtatttctca acttctcctt catatatatt tatacttaaa
    10021 ttttctcctg tataataata tatttcacac tcttcaaaac cttcacttag agccttttta
    10081 aataatatat ctttaaaatt tttaagttcc acaattatcc ctcctatctt ccacctacag
    10141 taatttcttt tacccttatc ataggttggc ctacattagt tggtatactt cctgatgatg
    10201 agccacacat cccctgagct tgttttacgt tattcccaat catatctata ttcataagta
    10261 tatcgctacc ttttccaatt aaactagcac ctctaactgg ctcttgtatt tctccatttt
    10321 ttattaagta accttctgaa actgcaaaat taaactctcc tgttacagga tttacagaac
    10381 caccacccat ttttttagca taaagtccat ctggtattga ctttataata tcttctggtt
    10441 tatcctctcc agcagcaata taagtgttag tcatccttga agttggtgca aatttgtagt
    10501 tctgtctacg agaacttcct gtaggattca ttcccattcg tctaccatta agtttatcta
    10561 tcatataaga cttcaaaatt ccattttcaa tcagtatatt cttttgagtt ggatttcctt
    10621 catcatctat attcatagaa ccccagtagt ttggtattgt accatcatct atagctgtaa
    10681 tctttgtgga agcaatctgt tgacctaatt tatctgcaaa tacagagttc ccctttgcaa
    10741 ctgatgtagc ttccaaagaa tgtccacaag cttcatgaaa tattactcca ccaaatccat
    10801 tatctattgc taccatcata ttacctgcag gacaattttt agcatgcaac atagtatgtg
    10861 ctactctagc tgattctttt gcataatatt ctgggtctat ttcttcaaat atttcaaacc
    10921 ctttacaacc tccaggacct tcaaatccag tttgattttc attaccctta gatgcaattg
    10981 aacttatccc tagtctagtt cttattcttc tatcctcaac atatatacct tcagtgtttg
    11041 caattaatat tttttggtct ttatccaaat aactaacact tacttgagat atatcattac
    11101 taaattcttt tgcactctta tatgcaacct tcataacact tactttatct ttatttccta
    11161 ttgaatttgg ataaattttt atattatgta tgttatttat tttaatactg tcatttaata
    11221 ttacactttt tccatcttcc aatttaccta aagcaacagc agctttgtat gctacatcca
    11281 acagactatt taatgaattg tcacttgtat aagcatatat acttttcaat cctttaaata
    11341 ttcttattcc tataccataa tttcttccac ctattgcatt ttctacttta ttatctatta
    11401 aactaataga attatttata gtgtcttctt caaaaatctc agcaaaatct cctccagtaa
    11461 ttagacactt ttctaatacc ttagaagcta tattttttga aagcataaat ttacctccta
    11521 ctttaaattt ttaattaact tttattcaat ctttttactt gttaacaaac attatatact
    11581 atattactta aaataaggta attatgaata tattatacat atgttttata ctaaaatgtt
    11641 atcacatttt atctatacat acccatataa ctagataatt aaaatgtata atattatttg
    11701 ctatagaaaa taatacactc atacataata aattttagga gtgaagtata tgaatcaaga
    11761 atatgtaaaa ggaaatccta tttttactaa tattaataaa gttccaagac aatttccata
    11821 ccttactgat gatattgata ctgatgttat aattgttggt ggtggcgtaa ctggatgtat
    11881 ctgtgcttac tatctagcta aaaacaatat aaagtctgtc attcttgaaa aaggaaggat
    11941 tgcacatgga agcactagcg tgacaacttc tctattacag tatgaattag atgacaattt
    12001 gatagattta acagaggtta tgactctaaa agatgctcta aaagcatata acctttgtac
    12061 ttcagcactt gaagaattag atacatttat agagctatat ggaaataagt gtgattatgc
    12121 caaaagagat actctacttt atactgccaa caaacttgaa gttaaggcta tcaaagaaga
    12181 atataactta agaaaagaaa atggatttga tgttgaatat attgatgaat ccacaaaccc
    12241 ttttagcttt gatttaaaat caggattgat agcaaagaat ggaggacgag aattagaccc
    12301 atataaatat agtcaccatt tgattgatgt aagtttaaaa aatggtcttc aagtatatga
    12361 aaatacagaa gtaaaaaaag tagatttatc aaatgataag gttactgctg aagtatcgta
    12421 tggatacaaa gttcatggta aaaaattaat tgtagctaca gggtacaata caagtttatt
    12481 tacaaaaaga aattttgcaa ctaagtcaaa tacttttaat atcgcaacga aaccacttaa
    12541 aaacatagct tcttggaaaa acaacatttt aattagagat aactgtgacc catataatta
    12601 tctaagaact actaaagaca atcgattaat tataggtggt gaagatgtaa gttttgatga
    12661 tatagaaaat gaaactttag ccaatgaaaa gtacgatatt ttagaacaaa gattgaaaag
    12721 tatgtttaag gatataaaag acattgaagt tgaatataaa tattgtggtt gttttgcttc
    12781 aactttagat aatttaggtt ttattggtcc agataataaa aataacaatc tatggtattg
    12841 cttaggttat ggagcaaatg gtatactctt tgcaatatta ggaggtataa tgttaagtga
    12901 attatatctt ggcaaacaaa ataaaaatat gaaattattt aaagtagata gatttgataa
    12961 atagatatta tatattaaaa gactgtaaaa agatgaaact ttataattct aaaagttaac
    13021 tttgatacag tcttttataa tgttcctttt aaaaatactt tatttataat taaatataaa
    13081 gtaaaatgtt aaaatataac taataaaatt tagtcataag ataatattta agtttatttg
    13141 atgaaatatg gaggaattat tatgaaggaa atactcgtta ttgctcccac taaaggaacc
    13201 tatgaaaaat caattcacat agttaaaaaa aacaaatata caaatattga tgttgtattt
    13261 ggcaatctaa aagaaggtat acctcttgct gaaaaaagta ttaatcatgg tactagaatt
    13321 atcataagcc gaggtggaac ttacaatatg ttaaaagcta cttacaatat acctatagtt
    13381 gaaattaagg tagatgctta tgatattata aaaagctaca aagaggtaaa aaattccaac
    13441 gaaccatttg gaataattgg atttaataat gtcatctacg gtttcgatat tatagaagaa
    13501 atattgaata agaaaataac tatgattgaa attgaaaaag aagaagaaat ttatgatgct
    13561 atagaaaagt acagaaagaa aggtataaac acatatatag gagataccac tgttgcacat
    13621 attgttaaga gacttaattg taagggaata ttaatcgaat ctagagaaga aaacatactt
    13681 agagccattc aacaagcaga gcaaatactc gaagcaacca aggatgaaca aaaaagaaga
    13741 ttacagatag aagctatgac agattttgta catgatggaa taataacagt tgataaaaat
    13801 tttaaaataa cattatttaa taagagtgct gaaaaaatat ttggtataaa aaaagaaaat
    13861 gcactttatc ataatgttgt agatgttatc ccaaacacag ttcttccaca agtagttgag
    13921 actatggaac ctcaaattgg tgaaatacaa aatataggga gtacaaaaat tattacaaat
    13981 agagttccaa tcattgttga tggtcagatt caaggagctg tttcaacatt tcaagatagc
    14041 aaggagataa gttcttttga acatacaata agaaggagct tattaagcaa aggtctatct
    14101 gctaaataca cttttgatga tataattcat gctagtgaaa agacaaaaga ttgtatagaa
    14161 cttgcaaaaa aatatgcttg ttatgatact cctatgatta ttactggaga atctggagtt
    14221 ggtaaagaac tattttgtca aagtatacat aactatagta agcgtaaaaa tgcacctttt
    14281 gttgctgtaa attgtgctgc catacctcca tctctaatag agagtgagtt ttttggttat
    14341 gaggaaggtt catttacagg tgctagaaaa aaaggtaaag caggtgtatt cgaactagca
    14401 catgaaggca caatcttcct agatgaaata agtgaaatcc ctcttgaact tcaaggtcga
    14461 ttattgaggg tattgcagga aaaacaagtt atgagaattg gtggtgataa agttattcct
    14521 atagatgtaa aaattatctg tgcttcaaat aaagacttaa aaaatatgat gcgcaatggt
    14581 ttatttagac aagaccttta ttttagaata aatatactaa cattatatct tccttcatta
    14641 aaagaaagaa aagaagatat tataaaatta tcagaatttt ttatacataa atattcaagc
    14701 aaatacaata aaacgccttt aattatcact ccaaatatta aaaaggcact tcttgaacga
    14761 gaatatgaag gtaatataag ggaattggaa ggtatgatgg aaagggctgt tattgtggaa
    14821 tcatttgact cgattttatt agaaaagctt agcaatgaat atacaaataa tatagttgat
    14881 aaagataata gtgattttga atgcagtaat ttagatttaa aaactttaga aaaaaaatat
    14941 atctataaaa tttataacga aaataataga aatactacaa aaacctgtga aattctaaag
    15001 ataactcgct ccactctatg gcgtaagtta aaagaaatag aagatgatgt ttaaaaataa
    15061 tacatatcta tatatatcaa aacgttttat gtttaatttt aatacataag acgtttattt
    15121 gttttcaata aaaaatacaa ttatatgata aaaagaatct ttgtaagtga aattctcgtc
    15181 aatcatactt ttaattataa gtaatctaca gcatttcaat cgattattaa aaataatcat
    15241 aataactaaa gatacaaact ctatatattg gcatagtaat tgcttttata atacctatat
    15301 aaaaatgaaa gggagtgata ctagatgcac atcttaaaat cagtgaaaaa gataccagga
    15361 ggacttatgg tctgtccctt gttatttgga gcactattta atacagtatg tccacaagct
    15421 cttgaaattg gaggattcac aacatcctta tttaaaactg gtgcaatgag tatacttgct
    15481 ctattttgtc tatgcaatgg agctcaaatc aatatcagac aagctggtaa accattgact
    15541 aaaggtatag tacttacagc aacaaaattt ataattggtg cagtattagg tattattgtt
    15601 agtaaattta ttggacctaa aggtataatt ggtattacac ctcttgccat agttgctacc
    15661 atgactaatt caaatggagg tctatttgct gctcttgcag gtgaatatgg agactccaca
    15721 gatgttggag caatatctat cttatctcta aatgatggtc ctttttttac aatgcttgct
    15781 tttggagtaa ctggacttgc aaatgtacct atagtagcac tatttgcagc acttatacca
    15841 atactacttg gatttatact tggtaacctt gatgaagata tacgagaatt tcttgcacct
    15901 ggtacaacat tattaattcc tttcttcgct tttcctttag gagcagcatt aaactttaat
    15961 caaattataa ctgctggact acctggagtt gtacttggtt taggagttac tataataaca
    16021 ggtatgggtg ggtactttgt aatgaaactt atacgtgcag aacatccagc agtaggtgca
    16081 gctacaggta caacagccgg aaatgcagct ggtactcctg aagctttagc agctatagac
    16141 cctactctag ctacaatagc agctgtttca acagtacaag ttgctgctgc tattattgtt
    16201 acagcaatat gttgtccaat gttagtttcc tatctagata aaagagaaaa aaagaaaaaa
    16261 tctattttta aaacaaataa aaatattgaa gtaaattaat acttaaggag gtaaaattaa
    16321 tgaatgcaat tattcatgca aatgaaaaag ataatctagt tacatgtgtc agacctttaa
    16381 ttaaaggtga aaaagtttca attgatggaa agtcttacat agtaaatgat aatatacctg
    16441 tctttcataa gatggctaca gaagatgtaa aaaaaggtga tgttgtatac aaatacggtg
    16501 aaattatagg aattgcaaca gttgacataa aaactggtga ctatgttcat gtacataaca
    16561 ttgaaagtac acgtggtcgt ggagataaaa aataggagga agttaaaatg aaattaatgg
    16621 gttatttaag agaaaatggt cagtttggta ttcgtaatca tgttttaatt attccaacat
    16681 ctgtatgttc aagtgagaca gctacaagaa tagcatcact tgtgcctgga gcaatagcaa
    16741 tccctcatca acatggatgt tgtcaaattg gttctgatat agaacttaca gcaaagacat
    16801 taataggatt tggaaaaaat cctaatgttg ccgcagtttt agtagttggt cttggatgtg
    16861 atggtattca agcaaaagaa ttagcatctg aaatagctac aacaggaaaa aaggtagatt
    16921 acgttgttat acaagaatgt ggtggaacat taaaaacagt ttctaaggga gctgaaatag
    16981 taagtaaaat ggctcgtgaa gtatcaaaag aagtaagagt tgaatttggt atgagtgaaa
    17041 ttacattagc acttgaatgt ggtggttctg acccaacaag tggaatagct tcaaaccctt
    17101 caataggcgt tgcatcaaac cttcttgtag atgaaggtgg aagtagcata ctaagtgaaa
    17161 ctacagaagt aattggtgca gaacatttgt tggctacccg ttttgaagat gaagaaatga
    17221 aagataagtt tcttaaattt gtaagtgatg tagaaaaaag agcaattgct atgggagaag
    17281 atttacgtag tggtcaacct actccaggca ataaagctgg tggactttca acaattgaag
    17341 aaaagtcact tgggtgtatg tataaggcag gcaataagcc attcaaaggt gctcttgaat
    17401 atgctgatat tgtacctcct gataaaaaag gattatattt tatggatact ccaggtcaag
    17461 atatagattc tatcactggt atggtagcag gtggtgcaca aattgtaatc ttttcaactg
    17521 gtagaggtac tccaacagga agccctattt caccagttat taaaatcact gggaatagtg
    17581 atacatacaa caaaatgcca gacaatatcg atataaatgc aggtagaatt ataacagatg
    17641 gtgctaaaat agcagatata ggtcaagaaa tatttaatga aataatagaa gtctgtaatg
    17701 gtaaacatac caaagctgaa agtcttggtc atagagaatt tggcatttac agaatttcat
    17761 ctacatttta gattgtaaca aaatatcttt tataaatata atacttatgt agatacataa
    17821 gctaaaagtt ctttctaatc ctataaaaat tttctatact gaaaaggaac tgtatcaaaa
    17881 ttattttgaa aatagttcct tttttcacct cttttactca aaatattata aaataagatt
    17941 taaacaataa acgtatcttg attaatctct aagaagacat aaataaagct aaatgtaaag
    18001 tgagataaat aaaatttaat atctttgtat gaaaagatat ttggtataat atgtctgaga
    18061 gaattcttat ttgtaaacaa ataaaggatg gaggatgaaa caaaagaatg aactttgaaa
    18121 acacaaaaaa taaaaaaata atagctactt tactattgac actcctttta atcgtgtcat
    18181 taacatgtgt cacttttatt atgaatctaa ataaagtaac acataatgaa acagaacgat
    18241 atcttgtaga agtttcacaa agtatttcca ctacaattaa tgtgaaatgt aaaagtatat
    18301 ttaggacact atattctacg ggagatactt attttgagat taatgatagt gaaaaagaag
    18361 tcaataaata cttatcaaaa aaattacaat tatttgaatt tgattggtta ggtattatag
    18421 attcaaatgg aaattttata agtgccctta aagatacagg taatgttaaa ggacaagact
    18481 tttatagaaa agcccttcaa ggtaaagaaa caattactcc tgttaaatca caatctggta
    18541 catatggaat tttatattct gtaccactat acaaaggtga taaaattgtt ggagctgttg
    18601 ctgcttggaa tactattgat actatgagaa atttattaag tgtagaaagc tttcatggtg
    18661 aaggattttc ccaaattatc gaccaagatg gaaattttat tgtaagttca gcaaacaaaa
    18721 atgctccaaa aaatgtggtg aatttttttg acatgattaa acaccaagga aaacaggttg
    18781 ataaaaataa acttgaagaa atgaaaataa acttaaaaaa gaacaaaact ggttctatat
    18841 attacacatt aaatgatggt atttctaagg caatgcacta tcttccatta caagaagaaa
    18901 atttatacct cctttcagtt gttccaacaa aaacagcaag tgcacagttt gatttacttc
    18961 taaaaaaagc aatcttcatc aatattttaa ttgttatact atttttattg cttattatat
    19021 tgattatgtt tataaatcaa aaaaacaggg cacaacttat aaaaatcgcc tatgtagact
    19081 ctgtaactaa aggttacagt aaagcacgtt ttgatatgga agctaaaaaa attatacagt
    19141 catcttcatc agaaagctat tcattagtat ctataaatat tcagaaattc aaacttatta
    19201 atgattcttt tggtagtgaa gcaggagata aaacattaaa gtacatacat gatgtcatta
    19261 gtaattatct agaaccagga gaattacttt gtcgagtttc taatgaccag tttaatgtac
    19321 ttattaaaac tattcctcaa aaagaaattc ttaagtacat agaaaatatc accaatgata
    19381 ttaatagttt caataaaaat gaagaatgta aatactttat agctctatct ataggtgtat
    19441 ataaaattga tgacccaaat ctacctttag tttcaattca agaccgtgca aatgttgcac
    19501 gaaaaaataa taaaggaaac attggaaatc atccacttta tacatgtgtt ttttatagtg
    19561 atttagagcg tttaaaaatg attaaagaaa aagaaatgga aaatagaatg gaggaagcat
    19621 taaataataa cgaatttata gtatatcttc agcctaaaat aagcctcaaa gataatacta
    19681 ttgtaggtgc agaagcatta gtaagatggc aagacccaaa taaaggtctt ataccaccag
    19741 acgagtttat tcctttcttt gaaaaaaatg gttttattac aaaactcgac cactatgttt
    19801 ttgaaaaagt atgcagtatg ataagaaaat ggatagataa tggagaaact ccaatacctg
    19861 tttcagttaa tttttcacgt gctaatttaa ataatataga ttttttagaa aaatacagaa
    19921 tgcttcgtaa taaatacaac attcctgcta agctcttaga aattgaatta actgaaacac
    19981 ttgtatttga aaatctccaa aaattaatta atataataga ccaaatccat gaagaaggtt
    20041 ttcaatgttc actagatgac tttggaagtg gatactcttc actcaatatg ttaaaagaaa
    20101 taaaagttga cacattaaaa cttgaccgtg ctttttttag ctcacctaat gcagataata
    20161 ttgctgaaaa tcatgtaata gaatctatag ttaatttggc aaaaaaatta aatatgaata
    20221 gtatatcaga aggtgttgaa acaatcttgc aaatggatta tcttaaaaaa attaattgtg
    20281 atatgataca aggatatgtt ttttcaaaac ctctacctca agaaatattt gagaaaatga
    20341 cttttggaaa aaaactagaa gaaaccagta tggatagttc cgtttaaata aaataaaaaa
    20401 cttgtctcta taaaataatt ttaatcattt tataaagaca agtcttttta ttttccaatt
    20461 taattttatt ttctaaattt cttacactcg gcttgtttta aattcccttt ttaagaataa
    20521 taatacgatt atcatagcaa taaaatctgc aactggctgt gccaaccaaa caccatctaa
    20581 attaaattga attggaagta caatgattaa tggtataaat aaaataaatt gtcttaaaag
    20641 agttaaaaac attgaatgtt taactttact tatacactga aaatacacag gtcctacaat
    20701 agaaatcccc attataggca atgtaattag atttaggctt atacctctta ctgctatatc
    20761 catcaaatct gaatctttat taaatatacc tacaaatact tctgggaaaa cttgtactac
    20821 taaaaatcca aatgacaata tgacaactga cactatgata gataatatta aggttttctt
    20881 tgcacgctca tattgttttg caccataatt gtatgatatt atagtttgca taccttgatt
    20941 caatccaaac acaggcatca taaacatcaa taaaatagat gtaagtgctg tcatagctcc
    21001 aatagctaaa tctccaccat aaacctttag agaattattt gtaaacatgt gagttatact
    21061 tatagctact tccatagcaa aaggtgtcat tcctattgca aataccttct ttactatatc
    21121 tttattcaat tttaagttac atttttttag ttttaaattg gacttccctc ttataaaata
    21181 atgtattacc caaaaaaata ctactatttg acagagtact gttgctatag ctgctccttt
    21241 tatacctaaa ttaaatacaa atataaatat agggtccaat atcaggttta atacacatcc
    21301 tacaatcatt gtccttgctg ctaattttgg attaccttct gccctaattg cattattaag
    21361 agaaaatgca actaaattaa atatacttcc aaccaatatg acactcatat agtcttttgc
    21421 ataaaatatt gaatctttac ttgcacccaa aataaaaagt atctcttcta agaaaactaa
    21481 tcctaatata gttataatta aagagataat tatagataat gtcaaggcat tacctaatat
    21541 cttctctgct tcttctctat ttctttcccc taactttata gacaatcttg tgctagcacc
    21601 tactgatacc aacattccaa aagctattat tagagtaaat actggcatag ttacaccaag
    21661 acctgcaata gctatagagc caataccttc catagaacca ataaaagctc tatctactac
    21721 attataaagt gaagttacca tcattgctat tattgcaggt atcgaatacc taaataataa
    21781 aatccatatt ttttcatgtc ttaatgcttc ttgattctcc atgttgtcac catttacacc
    21841 atgtcataag ttatacaaat tggtttattt gttcttgggt ctgttgctat ttctgcatca
    21901 atattaaata attcttttag attatccttc gtcataacat catatgcatc accttcacaa
    21961 actattttac ctttcttaat acctatcatg tggtcagcaa atcttgctgc attattaagt
    22021 tcatgtatta ccatgacaat agttcttcct tgttttttat ttagttcatc taataatttt
    22081 agtatctcca attgatgtgc caaatctaaa tatgttgtag gctcatccag taataatata
    22141 tcagtttctt gtgccaaagc catagctatc catgcccttt gtctttgtcc tcctgataaa
    22201 tcttccatat ttctatcctt aaattctgca attccagtaa cttctaaact ccaatttaca
    22261 atctctctgt cttctttact agaattacca aatccacttt tatgaggaaa tcttccataa
    22321 gaaattaatt ctgaaacggt aagaccacta ggagcttgag ggctttgtgg aagtacagcc
    22381 atatcttttg ctatttcttt agacttcttt ttgtagatgt cctctccatt tatatatatt
    22441 ttcccactat tagggctaat aattctacct atagttttaa gtattgtcga ttttccacaa
    22501 ccattagccc ctatgatggt agttattttt ccttttggta tatttaaatt taaatttttt
    22561 ataatatctg tgtttccata tgatacattt agattcttag tatttataca gttcataaca
    22621 acaccctttc ctaatcattt accaacatta aataaataaa gtacggcact cctattatag
    22681 aaactactat gcctactggt atttctatag gtgctagaag atttcttgat atagtatctg
    22741 ctattaaaag taataatgtt cctatcaatg ctgatactgg tattaatctt ttatgctttg
    22801 gtcctattat ttttctacct atatgtggag ctattaaacc taaaaatgaa atactacctg
    22861 ctactgctgt cgatacacca gataaaatta ctgcatatat tataagtctt cttctttgtt
    22921 tttctacatc tacaccaaga cttatagata cttcatcacc caaatttaaa acatctatat
    22981 atttagattt ataaatagtt atacccataa aaatcactat aaatggaagc acagctatta
    23041 catatttcca actggttccc caaatgcttc ctgatgtcca tgccataacc ctattaaatt
    23101 cttgtgttgt aaatttcaat tggaatatcg tcaaaattga agtaaaagct atgtttacac
    23161 ctataccaat aagtagtaat cttgacgaat ttataccacc tttccatgca agagaatata
    23221 taagaaatgc tccaaataaa gctcctataa gtgcaacaat aggcattgta aatacagtca
    23281 agttactcat accttcatat acattaccat tcataaggta tatataaact actacaaaca
    23341 atgcagcacc tgaatttatt cccaaaattc cagaatcagc taaatcattc tttgtaactc
    23401 cttgaagtat tacacctgct gttgataatg cagaaccaac caaaagtgct attactattc
    23461 ttggtaatct taatttaaat attgcaattt catgattacg ctgaccctgc cctaaaaaag
    23521 tctttataac atccattggt tctatagaaa atgagcccat atttaaactc aataaaaaag
    23581 tgataaaaat aagcaccatt aaaattgata taacaagtaa tgttttagaa tttattttta
    23641 taatattttt catagtacct atttctcccc ctttctaaca aggtatataa atattggcac
    23701 tcctataagt gctgttatag aacctactgg tgtctcatat ggaggattta tcatcctact
    23761 taatatatct gtatatacaa gcaatacagc tcctaatact aaagagctcg gtattatata
    23821 cttataatct gaacctacta ttcctttagc tatttgagga actataagac ctataaaaat
    23881 aatattacca gacactgaca cagatgctcc agtcattaat attacaagta ctatacatat
    23941 aaatctaaca aagttagttt tttgtcctaa tcctattgcc acttcttctc caagacttaa
    24001 tatagttatt cttggagcca taataatagc taaaataaat ccaatacctc cagctataaa
    24061 tagcaatttt ataccttccc acttcactcc tacaagccct cctgatatcc agaaactcaa
    24121 ctgttgagat aggttaaaat acatagatat tgctgatgcc aaagaaatta acaatgtacc
    24181 aagagctact cctgcaagtg ctagttttac attattaact cttcctcttg atttagaact
    24241 tataaaatat ataaataatc cacttatact tgccccaata aatgcaaaca tcattacact
    24301 aaaacttcca tgtataagtt gaggaagttt tttttgaagt accagtgata tcgaaattgc
    24361 aaatgtagcc ccttgtgtaa ttcctataac agatggttca gctataggat ttctcgttat
    24421 tccttgcatt attgccccgg aaactgctaa aaaacctcca acaagtgcag ctgctattgc
    24481 ccttggaagt ctaacatcct ttactattct catatttatt ccatcttcca tttttatcaa
    24541 gctatctata acagttgata gattcatatc ttttgcccca atagttatgg ataatacaat
    24601 tccaaataca agtacaacta tacttactaa tatcaacaaa taagttatat tttttttact
    24661 taacttagtc aattatccta cctccttttc ccttttaatc gtcagtataa tatcatctat
    24721 taagtatttt aattttaagc tttattaaaa ataggtgtga aaaatgaata tcattatctc
    24781 acacctacta agttaagaat tactttgtta attcattttt aactgattct aataataact
    24841 cttttccaat tggattgtat gattgactga aaaatggagc agcgtcaagt attgttacat
    24901 tgccatcttt tactgctctt atttgagccc agatagcact attttctaaa tcttttttat
    24961 ctgattctgt agcaattaca actatatggt ctgcatctat atctgttaaa ccttccatac
    25021 ttaccattgg tagtgttatt ccatcctgtt ttggcatatt cttaggtcta gctaatttca
    25081 tatcatcatt gattagagta cctattccac catcgctaaa taccataaat tgacctgaac
    25141 ttgccaacac tggtaaataa gttttttctc cattcttttc tataacttcc ttacctaact
    25201 ttgtagcttt ttcatcatac ttctgtagcc aacttttagc ttcttcttct ttgtcaaata
    25261 actttgaaac atcagttaac ttgcttctcc agtcatttgc ataatctttc atcataacta
    25321 caggagctat ttcttttaat tggtcatata ttttttcttg tctttgactc attattatta
    25381 aatcaggatt tacttctaat atagcttcca tatccatagt atccatcatt gagtgcccaa
    25441 ctatctttac acctttaagc tcttctctta tgtaacttgg taatttatca gtttcatatg
    25501 agtctacatt tgctgttgca acaggcttat aacctgctaa taatagttct tcactacttc
    25561 ctgatatatc aactattttt ttaggatttg atggtatctt aacctctcct ttaacagatt
    25621 gtacaactct tgtctctgat ttatctttat cctctgtatt cttatctgaa catgctgtaa
    25681 caagtactaa tgtagttata atagatataa atattgcaag tgattttatt tttttcatga
    25741 ttacttctcc tacttgttta ttatacttac atgatattga ttatcataag cacatattta
    25801 ttatagcatt tttctatttt tagtcaatat tattttgtaa aaggataaaa attcctaatt
    25861 aatcttaatt atatatagct tagataaggt tttcttatat taaacagtat ttttttaaag
    25921 aattggacac aaatacaatg acttttaggt taaacaatga taaaatgcaa tttatagata
    25981 atgaatttag taaggaggat tcaaaacatg gtacatttag tatattgtga taatgcagga
    26041 aaaaaaggag aaaaggtctt agataaaatc ttggctggaa caaaaacaat ggttattaga
    26101 ggtgctgctg gtagaaaaat accacatagt agagtatttg aagatgagtt actttatttt
    26161 atggaaaaag gaactgcaaa aatatctgca aaagccactg ttaaaaaggt agaaaactat
    26221 gttaaattaa cagaagatga aatttctaaa attttaaatg aaaatcaacc aaaattaaat
    26281 ttatctgaaa agcaaaaagt tcgttggcat aaaaaatgtt tatgcttagt tgaatttgaa
    26341 aatgttgaag aaataacacc tcttgatttt gaccatcaag gaaatatgga tgattggctt
    26401 attgttgaaa aaattgaaga tgtagttgtt ggtactagta taccttacaa ttatgagaag
    26461 tctaaatttt aaagtatcaa taacataata ctatattgct aaactctact taaataaaaa
    26521 aagagtgcat ttaataatta taaaaattat ttttatacac tcttttttaa taataatttt
    26581 aaattactta ctttctaatc tttcatatac atctataaat tcttctgcta attgttgaaa
    26641 attcatagct gtcattaaat ggtcttgtgc atgaataagt ataacactta tttcagtttt
    26701 attaccatta gcttcatttt gtatcaattc tgtttggaat ttatgagctt tatgaattga
    26761 ttctttcgac ttttcaatac attctctagc tttatctata ttcccgctct ttgcttcttt
    26821 tattgcttca aatgctagcc ctttcgcatc acctgcaaat ccaattattc caaaagatat
    26881 ctctatcatc ttctcatcca tttattcgac ctcctaaata tctctatagc ttgatatgac
    26941 taatccattc ttttctaaaa attctttgac ttttttagat gtaagtatct tgtgctcttt
    27001 cgttctatca atagcataag atgtagaatt taaaatataa tcatctaaaa aagctgggtg
    27061 agacataata tccactacat catacttcat tatttcgtct atatttttta taaaatattc
    27121 ttcacttaca ttttccttat aaaaactatc tattaaagga actactttag aatactctaa
    27181 attatattca aatccacctc ttattggaag attatacttg gttacaatct tctctattac
    27241 tggctttaaa cttactaaag tatggatatg atggtgacta tctaaatgag atatatctat
    27301 tccaagccct tttaccctat ctatttgagc acaaagttct ctataaatct catcacaatc
    27361 cattttttca ataatttcgt ctgtaatcct cctaataaaa aaaccgtctt tatcaacaat
    27421 agtttttaag ttagataata atggtctacc acaacttaaa gtcatatgaa ctccacaatt
    27481 taaagtttta ttttctttaa gtaagcctac tccatgttct accccaggca tatttgccat
    27541 catagaagta gacctaacta taccattatt atgagctgaa attattccat agttcacagc
    27601 ttcacaatat ccaaaatcat ctgcatttat tataatttta gtcataccat aacctacttt
    27661 ctatagacaa ctatctatta aatctaggaa gataatcttt atgagcttcc aacatttcgt
    27721 ctaatatagt ttttgctaag tcatcagatg gaatcaatgg gtttatacaa agtgccaaaa
    27781 gagcagattc ataatcgcca tatacagctg ctttagctgc caatacttca aatgatttaa
    27841 tttgacttac taatccatgc acagaatctg gtaaatatcc tatacttatt ggttttggac
    27901 cattttttgt tattacacta cttacttcta ccgcttgttc atctttaaaa tctcttatag
    27961 aacccttatt taatgtatta actacttgga tatctttttt gtcgttgtat atagaactta
    28021 ttaaattaca agcagcatca ctatagtaag cccctcctct tttttcaagt tgaggtggtt
    28081 ttacatctaa tttttcatcc ttatataatt caaataattg ttcttccaat tctttaacta
    28141 cttgacctct agcttttccc tctttaaact ctctcaactc atcctcaagc atttctttag
    28201 ttttatagta gtatctatga tatggacaag gtattgcacc caaagatttt acaaattcag
    28261 cattaaaatc aattgccttt atattttgca tacttatatc tgctttgaca aatttatcaa
    28321 ttgcttcttt tgtaacatct tctccatcta aagatacatt tagaccataa accatatgat
    28381 taagacctgc aaaatccata cttattctgt cactttctac attaaatagt ttggcaacat
    28441 cattttttaa atgaattggc acgttgcata gacctatata tcttctaaaa ttagtatatt
    28501 tgaatacagc ctctgttatt attcctgttg gatttgtaaa attcaccatc catgcatttg
    28561 gacataattc ttccacatct tttattatat caaatataac tggtattgtg cgaagggctt
    28621 taaataaacc tccagcacca ttagtttcct gccccataac tccatgagat aaaggaatag
    28681 tttcatcttt tattctcgca tctaaaagac ctactctaag ttgtgttgtc acaaagtctg
    28741 catctcttag agcttctctt ctatctaaag taagatttat tttcatatct actccagctt
    28801 tttttaccat cctcttagct agatttccaa ctatctctaa tttttctttt ccagcttcta
    28861 tatctacaag ccataattcc tttacaggta actcttcata tctatttata aaaccctcta
    28921 caagctcagg agtataactt gaacctcctc caattgtaac tatttttagt ccctttttca
    28981 tctcattata ccatccttac ctataattta atatactcta caaaacccca tacatttatt
    29041 taaaactcta tacatttatt taccgaaata aaactaccta gttgttaatt ttcaatttat
    29101 tagcttccat tttttcagac gctatgacaa atggaatata tattaatatt gataatatta
    29161 aattaaatag tgctaaagct ccaccagtcc agtcacctgt agccattgct ccacctaata
    29221 taggaggtgt tacccaaggt attttaggta aaattactgg tgctactaat ccaaaatcta
    29281 ttgctaagta tgatacagca ctacatatta ctggtgcaag tacaaatgga atcataaata
    29341 taggatttaa aactattgga agtccaaata tcaatggttc tcctatgtta aatattgcag
    29401 gtggaccacc taatactatc atctctttac gtcttcttcc agctattaat aaagctacta
    29461 ttaatcccaa taccattcca gaaccaccta aatatacaaa tgcatcaaag aatgcacctg
    29521 caagtacatg gtatccttcc gttgctcctg cttgagccaa ggcagcattt tctccaccta
    29581 atttcataag tatagtttct gtaaaaggaa gtgctatatt tgcaccatga agtccaacag
    29641 tccaaagtat atgaattata aatgcaataa gcattgtaga acctaaacta tcagctacat
    29701 ttgatagtgg tgctcctaaa taagtattta aaatatctgt taagaaactt ccattagaaa
    29761 gcatttttat aaatattcct attacagtaa atatcattat agttaacatt cctggtatta
    29821 actttgcaaa tgatcttgaa actgctggtg gaactccatc tggcattttt atagttaatt
    29881 tctttacctt agataatctt acaaatatct cagttgataa taatcctatt aatatagaag
    29941 agaataaagc tgctgtacct aagtaagttt gttgtatcat tccccatcct tcaactactg
    30001 tagttcctcc ctcaggaact attttaccaa tttgtggagc cattataaaa aagatagata
    30061 aagctataag cccagattgt aacccatcac tctcataaga ttttgctaga aaataagcaa
    30121 cacctattac taagaatact gccattgtac ctattgctcc ccaccaaagg tcgcctccaa
    30181 atgtggtcca gttttctcca aatatacttg ccatcaagtt tttgtatgct tccaatggta
    30241 agttatttat caatgttccc aatgcaccta ccatagttat aggtatcatt actataaatg
    30301 catctcttac tgctactaag tgcctttgag ctcctatttt agcagctaca ggcactatat
    30361 atttatccat aaatgacatg aatttttcca ttttacatcc tccagtacaa ctttattttg
    30421 aactatttaa ctctacagct ctatctaaca cagcttttcc attacatctt ccataatcca
    30481 tcatatttat aacttctact ggaatattat atggttttgc catttcagtt gcttttccta
    30541 atacatatct aacttgaggc cctaaaagta agacatcaca attttctatt tcatttttta
    30601 agttcacttc tgatatagcc catatttttg cttctatacc gttttccttt gctgcatcct
    30661 ccatttttgt aactaataaa ctagttgaca ttcctgctga acaagctaac attattttta
    30721 tcattttttc ccctccaaat tagattcatt aaatattttt taagtcataa gttttttaaa
    30781 ctatacattt aaaatatgct tttctattaa ttttttctta atgtatatat cttattttta
    30841 aatgtatata catttaattc ttgatattat tatataccaa atgtatatac atttcaagaa
    30901 aactttttca ttttatttaa attttattcg acaacagcat tcaaagttaa tgtatatcca
    30961 tagtgatatg tgtgtgagta ctcaaaaatc tcactatttt gtaacttaca aatttggctt
    31021 atatataaaa gtggctctgg ttcttctaat tttagattat ccatacattc ttcattcgat
    31081 attacagctt gtacttctct ctctgacatg gctatcttgt atccacacac ttcttcaaca
    31141 aaattataaa gagaattttc acaatgagtc ttatttaaat ttggaaataa cttaactggc
    31201 atataagtaa tcatatatga aactcttgca tcattagcta atcttactct ttttatttcc
    31261 caaacatttt cttctaaact tatattcaac ttacttgata aattttcatc tgcctgaact
    31321 atttcaagag ataccaatat attagatact ttatagcctt tactttccat ctctttagta
    31381 aatccactta cagacgatat attatcatat atattatttg caataactat actacctaca
    31441 cctctttgtc tagttatata gccttcttta actagattat taagtgcaga ccttacagtc
    31501 attctagtta cattaaattc ttcactcagc tgtttttcag aagggattaa atccccttct
    31561 ttcaaactgt ctgaatttat taactctcta acatgatttt ctataacttt ataaattggc
    31621 tctttcattt aattcactcc ttattaaatc ttttatataa taagataatt ttatatacaa
    31681 acaaagaaaa tgtctataca tttaagataa tttaaatttt attcagaaat cttgtacaac
    31741 tttccgagtt ttaataaaga tataaataga cttatcatta atataccttt taatatactt
    31801 gataaggtta tactccacca tacaccattt agacccaaca tttctggtct agatataaag
    31861 taagccaatg gtactcttgc accagtcagt atagtaatta taatagaagg tatataggtt
    31921 ctccctaatc ctttgaaagc tcctgttgtt attatttcta aacacataaa aaattgagaa
    31981 tagcctaata ttttaagata aactgctcct ttttctattg cctcactttc atctataaaa
    32041 atagaaaata tactctctcc tgcaaacact aatactaaag tagttattat accaagtaca
    32101 gaagatacag ttatagctat tttgcaacct ttatttattc tagaatactt cttggcacca
    32161 taattttgtc caacaaaact gcctaatgca actgatagcc cttcagccgt catccaggaa
    32221 attgcttcta tttgtgagcc tactttttgt actgcaacag ccacaggccc ccatgatgct
    32281 actattactc ctaatagcat tgagaatact gtaaacatac cactttgtat tgctataggt
    32341 aatcccaatt tatacagaac tttataatat ttagtctcta tttctttaaa tagtcttaat
    32401 ttaaaatatt cttctttact tttaactatt atatatataa aacatgtagt aactactatc
    32461 tgagcaaata cagttgcaat agcagctcct gcaacaccaa gttttggagc aaatccccat
    32521 ccaaaaatta atatagggtc aagtataata ttagttatta atcctactgt attaatacga
    32581 aaaggagttt tactatttcc aagaccattg aaaattgcag taaatactgg attaataaaa
    32641 taaaatacca tacctagagc tactattatc aaatactgtc tagacatggt tataacttct
    32701 aagtctccta atctaaaaaa acctatcaat tgtttattaa gtactattaa agaaattgta
    32761 tatattattg ctagtataat atttatttct attgctgact tcatatatga tttagtagtg
    32821 cttatattat ttgcaccaat actttgtgct acttttatct ctccacctac ttttgaaatc
    32881 ataataaatg ccattgcaag ccatggaaaa aaaccagctg ttccaactgc agctactgct
    32941 ttacttccgg ctttaccaac ccatatcata tctatcatgt tataccccat ctgtataaat
    33001 gaagtcccca ttattggaag tgatagctta agtaattttt ctgtaattct tccttctgtt
    33061 aaattaagtc tgtctttcat tttccacctc ttttatatta aatttatttg cttatatagc
    33121 tagattaatc attttatttg attgagttca ctatccttca atttatatta tcatatctca
    33181 ggattgcatc tcaatcatac ttatgtttaa gatacagtat tttacctatc tatgataaaa
    33241 ttaatactta tgaatataaa tctagccatt tcatcaatac atattctaac ctttaactta
    33301 acttcaatta agtatacata tcgtaaccaa ttagaatatt ttatacggta tcttccatta
    33361 ataaacaacc aatatcaatg atttatatat aattttattt atacataaaa tagtatacta
    33421 taataataaa aaaactatat ttgaatgctt taagcatgtt tactaattgt aatttccaca
    33481 caaatttgat aatatatgaa tatattatgg tgaaatttat agatatatat taattatggg
    33541 gagattgtgg gaggttcttt tcacaagaca tttaagctat gaaaataaat aaaaaattca
    33601 atagagttga tatgcaggtt tcaatactta ctgcaattat tgtaataata tcttcctcat
    33661 gtgtatattt ttttaattat acactaactt ataagagcat gatatactct ttaagtgaga
    33721 ggtcaaaaca tatctatgaa tatgtagaaa gaaatattga taaaaatacc tttactgaaa
    33781 ttaattctaa agaagaccaa tcaaaaaagt cttataaaag ttctaaaatc cttttagaat
    33841 ctgtaaaaaa tactactgga gtcatgtatc tatatactgc taaaaaaaca aaagatggat
    33901 cactagtata tgttgttgat ggtttaaatt catctaggag tgattttaga aatgctggtg
    33961 atttgataga aaaagagatt tggggagacc ttaacaaagc attagataat catatattgt
    34021 tacctaaaaa gattaaatca acatcttggg gatacatatt tatatcgtat tttcctattc
    34081 acaatgatgt tggtaaggtt gttggagtaa taggaattga atttgaagca aaacatcaat
    34141 acaatacatt taaatttata agtatagtta caccaataat agcattatta acttgtctaa
    34201 tatcagcatt gattgcagtg attctattta aaagaatatc taatcctaca tatactgatt
    34261 ttgctaatac agattattta acaggcctaa aaaatagaaa tgcttttgaa atagatatga
    34321 ataacttaaa caattcaaat ctaaagaatc taatatctat catatcaata gatttagacg
    34381 gtttaaaaaa gattaatgat aaatttggcc atcagacagg agacttatat attaagcaag
    34441 caagtaaaat tatacaatat gtaataaata aaaaatatat agtttatcgt attggaggtg
    34501 atgaatacat aattattcta aaaaatttat ctcacaaaga aataaataat attataaata
    34561 atattaattt aaaaatagtt gaagaaaact caactaatga attaaaatta tcaatgtcta
    34621 ttggatatgc tatttttgat gaaaaagtag atgtttcttt atttgataca tatcgtcgtg
    34681 cagattctca aatgtatgat aacaaaagga aaattaataa acaatatcaa taataaattt
    34741 aaaaagtcta ttctttaaat aataaatcac aagaatagac ttttttaaat ttgtgttttt
    34801 ataagataaa ttatttaatt aaagtttgtt cttttttcta aacgattctt tataaattca
    34861 tatattactt tcactaatat atttgtgact aatattaaca cagctagtga tgctgcctgt
    34921 gcagtactcc ccttatcatc tagttgtaca attgatattg cagctacttt tgaacttgca
    34981 gtatatataa aaactaatgc tgatattgtc accatggagt ttaggaaaaa gtacataaag
    35041 ttctctaaaa ctgctggcaa acaaagtggt atagttacgt tcttaagaat tgatgcgctg
    35101 tttattccca ttgatttagc taccatatcc aattctttat ctactttctt aatagcagta
    35161 gtagctgtta taaatgctac tgaaaagaaa tgaactatat tacatataac cattataagt
    35221 aatgttccat ataatccatt aaacaaattc ttaatgtata ttgtatccat aaaattaaac
    35281 tctaatttat taaaaaataa tacataagct atacctaaaa ctaatcctgg caatgccata
    35341 ggcaatgtac ttaaaaaata cccaaatgat tttaaatatg gagctttttc tgttttttca
    35401 ttcaaatatg caaataagaa aacaaagctc gtccctagaa tagctgtcaa tagtgacatt
    35461 tttattgaat ttataaatgg tttaatccca tcaatactgt ttttcataga aaaatgttcc
    35521 agtgtcagtc ttaaatcata tggccaaact gatattaatg aagataagat tacagttaac
    35581 attacagcta ttataccaaa tgcaataatt cctacaaccc ctcctaaaat actatctctt
    35641 aacttattag ttttaacctt atatggaatt gactttgaag ttatatatga attttgattt
    35701 ttttcaattt ttttagttac tataaacgat attattgcag gtattaaaag taatattgat
    35761 acagttgctc ccattggcat attctgttgc cctataattt gcttatatac atctattgat
    35821 aatacattaa actctcctcc tatcaccttt ggagctccaa aatctgtaaa acataatgta
    35881 aacgatacga atgcagaact tattaaagag tattttatac ttggtattgt tatgcttata
    35941 aattctctta tcttgcttat ccccatagta ttactagctt catatagtct ataatcggtt
    36001 gaacttagag atatataaag tatttgaaat gattgaggaa atacatatat aatttgtgcc
    36061 aatattattc ccactgctcc atatattgga acatgcactc caagtaaatt agttaccaaa
    36121 ccttgatttc caaataaata tactagacct attgcatgca tcattgttgg agcaaacata
    36181 ggaaacatag ctaatgattt aaaaaaacct ttaaatttaa tctttgttct agttaatgca
    36241 tatgcatata ctaatgcaag tgttagtgat attacagttg atataactga tacaaatact
    36301 gtatttttta gagaatttaa tagagattca gaagccaagt attcttgaaa gttttgtaat
    36361 cctacaaaga ctccatcttt atctaaaaaa gcctgtacaa atagatatat tataggtgct
    36421 aataaaaata ttactaaaga cataactaat actgtaagca tacatttttt tatatctaaa
    36481 ttcatttttg atttaagact tatactttta gaacttatag cattattatt catacactta
    36541 tgctccttta acttttggat actttaaata gtatttttcg tctatactta tttttacaag
    36601 gtcaccttct actaaattta aattaaccca ctcttttata gaagcatcac ttattatgaa
    36661 attttcattt aatttatctt ttatttcaac tctcaataaa ttccctctaa actctatatt
    36721 tgatattatt ccttggtagt tttcttttgt cgatttctct atttgaacat attctggtct
    36781 tacagttaat atagaatctc cattatcaaa acagtttgta tctcctataa attgagctgt
    36841 aaataggttt tgaggatttt ggtatatttc ttctggagtc cctatttgca ttatatctcc
    36901 tccatttaga atagctattt tatctgccat agttatagct tcttcttggt catgtgttac
    36961 cattattgtc gttatattaa gttctttttg taatctttta atgtccattc taagcttgtg
    37021 tctaaccttt gcatctaatg cggacattgg ttcatctaaa agtaaaaact ttggttcaag
    37081 agctaatgct cttgctattg caatcctctg ttgttgccca cctgataatg ctttaggata
    37141 tttatgagct tcattagtca atccaactgt ttcaagtact tccttaactt tattatctat
    37201 ttttcctttt gaaacttttc tctcttttag tggaaaagct atattgttat aagcagtcat
    37261 attcggaaat aatgcatatg attgaaatac tataccaaaa cctctctttg atggctctaa
    37321 atttgtaata tctttatcct ggagaattat agttccgcta tttacatctt caagacctgc
    37381 tattattcta agtaatgtag ttttaccaca tccactaggt ccgagtaaac atagaaattc
    37441 tccttcttca atatccaaac taatattatt taaaaccctt ttttggtcat aacttttaaa
    37501 cacattattt atttttaagt aactcatatc ttatctctcc ttatatagtt atttttttat
    37561 tttaaatttt atatcctact ttttcttcta aaattctttc atctaaatta ttaatttaaa
    37621 ctttacttac tttcagattt tgaaccgtat tttgattccc aagttttaag tactgtactt
    37681 ctgtttttgg cagcagagtt taaatcaact tcttttataa gctgttcaaa tggttgttta
    37741 gaataacctt ttggaactgg attatctgtc tttatggaag taactgctac ttcatgtgca
    37801 tatctatcca tagctgaatc acttattgcc caatctaaaa atagctttgc ttcttttttt
    37861 atattatctt ttttaactaa ggcatttgct tctaagtccc agcctgaacc ttcctttgga
    37921 aatacaacct ctataggttc tccactagat aattgttgtg tagctctata tccaagtgta
    37981 atacctattg gatactctcc agagccagct aacttcgcag gttttgaacc cgagtgtgta
    38041 tatgtggcta tatttttatg taatttatcc atgtaattgt aagcatcttt ttcacccatc
    38101 atttgaataa gccctgatac tgtaagatac cccgttccag atgatgctgg atttggcatt
    38161 gttataagtc ctttatattc tggttttatt aaatcttcat aactttttgg aatatctata
    38221 cctagtttct taagttcctt ataattaact actattgctg tctctgggac actcattcct
    38281 acccaagata catcatcttc agtatcttta aattttttat caactttatc ataattttta
    38341 ggcttatatg cttcaagtgc accatctttt tttagctcta tcatgttcat tgctgataat
    38401 ccccatataa tatctgcttg tggattatct ttttctgcta atagttttga agctattaca
    38461 ccatgagaat ccataactat ctctacatct atattgggat actcttctct aaaaccttcc
    38521 atataataag ctatctgctc ttcctctagt gctgcatata ttgtaagttt attatttcct
    38581 tttccttgag tagtttgtgg tgttgttgat atgcaacttg tcataaatgt aatcactaca
    38641 atgcacagac aagtaaatat aaattctttc atatcttccc cctttgtgtt ttttcctttt
    38701 tttatttgtt ttttattgtt tttgcttatg tttatataat acacctaatt tgttaatata
    38761 aagttaagtg taaattaaca gttcgttaat ttttagaaat ttttgttaaa tatattattt
    38821 ttagttaaat acagtctgtt tttaaacaat atattaattt ttatagtatc tacattttaa
    38881 tttaaacata aaaaataagt ctaacctcta taaagtagaa tgttagactt atttttataa
    38941 gtatttaatt atacaaccaa atcatttttt ttcttttctt caagtgcttt tttaagcacc
    39001 atatccttaa ccttcataag tctagtagta cttgctctct cattttcttc aagcttcata
    39061 gctatatact taatagtctc aatgtaattt ggtatcatta cattttcaag agcattaaca
    39121 cgtctacgtg tcttttctat ctcttgtgca agaagctgtg cacttttttc actttctgca
    39181 agtcttaaaa gtggttgcat agcatctgag aaagcttcca tagcagaatc taattcacct
    39241 gatgtaaaag caagaccata aggataaata tcactttgat tgttttcagt tttaaagtca
    39301 aacacaggaa catcaacact cattatattt ctcgtagaaa catctactga aactgattgc
    39361 tttggcatca taagtgctga acccagatac tcctgactca taactgctct tgcgattata
    39421 aagtttttat aagcagtatc aagagcattt tctgcttctt cacgcaatcg cttattttct
    39481 cttacaatct caagaaattg tttcataagt tcatcaagtt tatctttaag aagcttatga
    39541 cctcttgtag cagttttaag gagtttctta agtctagtca tttccatacg tgttggattt
    39601 atatttaatc tagccacaga tatcactcct taggcatata tttttcaaaa tattcatcac
    39661 ggatacgttt aagttcactt tttggtaaca tactaagaag cttccatccg atttctaatg
    39721 tctgctcaat agttctatca gttctaaatc cttgtgaaac atattctttc tcaaattcat
    39781 ctgcaaactt agcatacatt aaatcaatct cagaaagtgc agattcacca agtatagcca
    39841 taagttcttt tgcatcctta cctcttgaat aagctgcaaa aagctggttc attgtatctg
    39901 catggtcttc acgagtctta cctttaccaa tacctttatc ttttagacga gaaagtgatg
    39961 gtaaaacatc tataggaggc tgtatatctt ttttataaag ttcacggcta agtataattt
    40021 gcccttctgt aatgtatcct gtaaggtcag gaattggatg tgtcttatca tcctcaggca
    40081 ttgtaagtat tggaatcata gttatagacc cttcatgccc tttcattttt cctgctcttt
    40141 catacatagt agcaaggtca gtataaagat atcctggata tccacgacgt cctggaactt
    40201 cttttttagc tgctgaaact tcacgcaacg cctctgcata gtttgtaata tccgttatta
    40261 taacaagtac atgcatatct tgctcgaaag caaggtattc tgctgctgta agtgccattc
    40321 taggtgtaga tacacgctct acagctgggt catttgcaag gtttacaaac actacagaac
    40381 ggtcgattgc accagttgct ttaaaatcgc ttataaaaaa ttcagcatct tcaaaagtta
    40441 taccaactgc agcaaataca acggcgaact tagaatcagt tccacgtact tttgcctgtc
    40501 ttgcaatctg aactgcaaga ttggcatgtg gcaaaccaga ccctgagaat ataggaagtt
    40561 tttgccctct aaccaatgta ttaagtccat ctatagcaga gactccagtt tgtataaact
    40621 cggccggata atcacgtgct gctggattta ttggagctcc atttatatca agtcttttat
    40681 ctggtataat ttctggacct ccatcaatag gtctacccat tccactaaaa acacgaccta
    40741 atatatctgg tgaaactcca aagtcaagac tctttcctaa aaaacgaact ttactttcag
    40801 caaggtttat acctgttgag ctttcgaaaa gctgaacaag tgcagtatct ccatttacct
    40861 ctagaacttt gcaacggcga atttctccat ttgaaagttc aatttctcca agttcatcaa
    40921 attttacacc ttctacgccg tttattaaca taagaggacc ggctacctct tgtattgact
    40981 tatattcctt tatcatagtt cttcagcccc cctcttttta ataaggtctg caagctcgtt
    41041 gtctatttca tcttcaattg aatcgtaagc tgcatctata tcgccttctt ctacatactt
    41101 agcacgacca atcttttcaa gaactgaaag cttgataata tcgtttatag taacattttg
    41161 cttgatagca tcttgtgctg acttatagaa ttttaatata agtcccatca ttctatattg
    41221 tttatgaagt gatgtataag tatcaacttc atggaaagag ttttgatgaa ggaagtcttc
    41281 tcttatagaa cgagtaacct ctagtatcaa tctatctcca tctgaaagtg aatcaacccc
    41341 aaccaattga actatttctt gaagttcaga ttcaacttgt aaaagtttca tagcttgagc
    41401 tctttgagct gagaaattat catttacatt tttatctgcc catacatcaa ctttttcctg
    41461 atagagtgaa taactagtca accagttaat tgctgggaaa tgacgtttat atgctaaaga
    41521 tgcatcaaga ccccagaata cttttactat acgaagagtt gcttggctga caggttctga
    41581 tgtatcacca ccaggaggag aaactgcacc aattgctgta agtgttcctt ctctttcatc
    41641 catacctaga caatttacct ttcctgctct ctcatagaat tgagcaagac gtgaacctaa
    41701 gtatgcagga taaccttctt caccaggcat ctcctctaaa cgaccactca tctctctaag
    41761 agcctcagcc catcttgatg tagagtctgc cataagtgca acactatatc ccatatctct
    41821 aaaatattca gctattgtaa taccagtgta tatagaagct tcacgtgcag caaccggcat
    41881 atctgatgta tttgctataa gcacagttct ttgcataagt gactcgcctg ttcttgggtc
    41941 ttttaattca ggaaattcaa gaagaacatc tgtcatttca tttccacgct cgccacagcc
    42001 tatatataca actatatctg catctgccca tttagcaagc tgatgctgtg taacagtttt
    42061 tccacttcca aaaggtcccg gtatagctgc taccccacct tttgtgattg ggaaaaatgt
    42121 atctataact ctttgacctg taacaagaag tgaatctggt gttttctttt ctctatatgg
    42181 tctttctttt ctaactggcc atttttgcat catagttaca ggtatatcat tacctttttc
    42241 atctgtaata acacaaactg tatcttcaac agtaaattca ccagaatata tttcttttat
    42301 agtaccctta actccataag gaaccataat tttacattct actactgctg tttcttgaac
    42361 gccaccaatt atatctcctg ctacaacctt atcaccaaca gattttttag gtttaaattc
    42421 ccacttagtt gttctatcaa gtgaagatac ttcaacacct ttagttatat tagtacctga
    42481 aatatcatac attttttcaa gtggacgttg aataccatca taaatagttg aaataagacc
    42541 tggtccaagt tcaacactca taggcattcc aagagaaact acttcttccc ctggtcctag
    42601 accggaagtt tcctcataaa cctgtataga agctttatct ccatgcattt ctataatctc
    42661 gcctataaga tgtttatctg aaactcttac gacgtcaaac atattcgcat ctctcatgcc
    42721 ctccgctaca acaagcggtc ctgacacctt tacaattgtg cctgttttca tattctctca
    42781 cctgcaatca tatactttat caaaatttaa atattccctc ctatatttta ttagcacata
    42841 tatttagcac caataaaatt tgagattgtc ttttattcaa ctttcatcta ttctttaaat
    42901 aatatatctg cacctatagc acgtttacta gattctctta cttcattcat acctaatccc
    42961 atacttcctc caatacctgg aataactata atggcaggaa gttggtaatc tttgtatttt
    43021 gctattgatt cttttgcaag caatgatgcc tgttctgtaa tataaattat cgcatattca
    43081 tcttcaacca acttatgtat acttttttta atttcgtcac tatcataggc tgggaagata
    43141 tctattccaa gagctaaaaa tcccatgatg ctatctttat ctccaactac tcctacctta
    43201 tacataagca tcccttagcc tttcttttat agtatctgcg tctatattat taagcttact
    43261 agtcaaaata attctaattg tttttatctc tgattcttta gcatataaat atgcaattag
    43321 tggttctaat gtaagaggct taaattttgc tcctctaaca tattccataa gatagtcatc
    43381 acaaagtttt tcaaagacag taaaaccact atccatgcca tttttacaga catcagagta
    43441 agaagtagat ttaaaacatg atgctggagt atctgaggaa aaagcttcta agaatttttc
    43501 cttatcaagt gagccacctg aaacaaacac attcataaac atatcaaaat ctttcttcat
    43561 atttttgact cttataaaac tctttagatt tgttaaatca caaactttca taacataatc
    43621 tattacaaat ttgttttggc tttctttagc agtttctttc atactggtaa aggttgcttt
    43681 atctagaaca atatcaacca tctggccatt ttgtgtctta ttataaacat caaatgcctc
    43741 taatatagct gatgacatta tcttaggtaa atcactaaaa ctacgatttg ctaaagattc
    43801 tctaagctta ataagaggaa ttgtacctcc atcaattaaa tatttctcac catctacacc
    43861 agaaatttct tctttaatca gcacttttaa attgtgatag tcatttttat aaagaaatac
    43921 atcaacaaat ttttcttcag gagctagact tttaagaatt tcatatgtct ttgataattc
    43981 ttgagtcaaa atattctcaa aattatgtat attattattt gatgtatcag cataacctgc
    44041 ctcagctata attcttaaag agtcttcagg gcttttggct tctgccattt gaataaacat
    44101 ttgtctgtta agaagctgtt tttcaagcac tcttattcgt gcaacggcat agggataagt
    44161 tttttcttct gccatttttt aacccctcct taattaaaca aaatttctgc tgcaatttgt
    44221 tcaatatatt catgctctac tgcaattatg gcttcaaatg aataattgta ctcaatgtca
    44281 ccttttttaa ctatgaaacc tccagtaata tctctagttt catcagacac tttaatgcct
    44341 ttttttgata gcacatcttt taatgttttt ttatcttttt tagataatac tatctctgaa
    44401 tcatctgtac aatttgattt ttcaatcatg tttagtataa tctcttcata ttcattatct
    44461 ttaagattta aaagtttgtt tttagcttct aaaattacct cttctaaaat ctcttgtttt
    44521 tttgataata tttgcttttt agcctccata taagctcctg atatttcctt agaagccgct
    44581 ttttctgctt ctgcctctgc aagctttgta taggaagcca tttccttttc agctttttca
    44641 ttagctgaat ttacttttaa atctgcttca cttttagctt tatccaatat ttcttgtgct
    44701 tcttgtttgg catcagctat aattctgtca atcatttttt gttcattacc cataggagtg
    44761 cttcctcctt ttcatttttt ttacttatga attataattt ataattaacc aattgcaatt
    44821 ccattgtaag ctaagaaaga aacaagtagt cctaaaagag catatgtttc aactattgct
    44881 gcaaatgtta tagctttacc aagttcttca ggtctttttg caactattcc aactcctgct
    44941 gctgctgctt taccttgtgc tatacctgat actaaaccaa ctaaaccaat tggaagtcct
    45001 gccataagaa gttgtaaacc ttgagctgat gttggtattg catctccacc aataattcct
    45061 gcttttgata aaataaggaa agctatgata aatccataca gaccttgtgt accaggaaga
    45121 agttgtaaaa ctagaagttg accgaattta ctagggtctt ctgttacaac acctgctgcg
    45181 gcttgacctg ctattgaagt acctttagca gaacccatac ctgcaaataa tgctgctata
    45241 gcagctcctg atattgccaa aaattgacca tttcctaacg cgtttaaaaa ttccatattt
    45301 acatctcctt tttattaatg cttgtatatt ttgttttata cttaaacgga acaaaaggaa
    45361 ctcctccgcc ttcataaaac ttattgaaaa attctacata ctgtaaccta cttgtatgaa
    45421 catatgcacc tagtgcattt ataagaaggt ttattgtgtg tcctacaaca ccaattacaa
    45481 ctgcaagtat cggaccagct atagctccta aaaggttgat aacttgtgct ataactcctg
    45541 ttgttaaaca aagcgccata attcttgtat aagataatat atcagcaaaa taacttgtta
    45601 taccatagag acttgaaaat cctttaaaaa gcttaacagg aataccttta aagcttcttc
    45661 cttgagtaag tacaagacct atagcaccta taattgctaa atattttcct acttctgaaa
    45721 atacacctat atcccctgca acaaaaggta ttataagtag acatacacct gttatacaca
    45781 aataccaaaa acctatgtca aagattgcat ctattacctt tccacttctt attaatgtat
    45841 atgcttttat tcccaaacct acatatatat ggataatacc gaacagtaac gacattccca
    45901 taagtgtcat aacatcctct aaaggattaa ttaatgcttt tataggaatt aaatccccca
    45961 aaataccccc gaatataaga ccccatacag tagttgaaac tccacagata ccaataagtt
    46021 taattaaatt tccttcacct ttttgtatct ttaatttata tacaacaaat ccacagacta
    46081 ctgcaattat taacccatat gcggcgtcac ttagcatcat tccaaagaat acaacaaaga
    46141 agaaagttaa aattgtattt gggtcaatat cttttgtact tggatagctg tacatgttag
    46201 ttacactttc aaaaggtgtt actaatttat tgttttcaag cagaattggg aagccttctt
    46261 ctttacttcc ttcttcagtc tgaacacaac aattaaactt ttctgtaatt tctttaatta
    46321 attcatctgc ccttttgctt ggtaaccaac cattaagaca gaatgttgtt tttgttttga
    46381 caagtctctc tataatcttt ttttggtctc tttctatagt gtaaaaatca tataggtttt
    46441 caagcatgtg tatactatct gcatgtcttt taatttcctc tgttttgtcc ttagaaacgt
    46501 tttcctgtct aattatcatt tcattgtatt tcttgatagc ttgtaacggt gtaccttctt
    46561 catttggtaa tgaaaccact gaaaaattaa attcttttaa aacttctaaa acatcatcaa
    46621 aagtttcttt taaagtaatt aaataaacat agttcattaa cttgtcagaa ttgacaatcc
    46681 caataacact ttctggtatt tcatcttcta attttactct taaagcatca atgtttgcgc
    46741 ttatgggcac agttccaagt atagtttttg tatacttagt ttccatattt tcaagaggaa
    46801 tatcaaagtt cacccatggt tctaacatac ttttattgtt gttaagtaag tttatgttag
    46861 accttattgt acctatctcc ttgtgcaaat tgtttaactc cagagcttca gcataaactt
    46921 gcccttcttt ttcactatca attttgttaa actctctttt tggtgcaagt agggattttt
    46981 tttgtttcac tagtgaagaa acaatattaa ttgcttggtt tacatgagac attttctgct
    47041 ctagcattat aacttcagat tcttcactat cttttacaag ataatttttt aattcctcct
    47101 cctcagtaag aaaggcacta tcatcaatct gaacaaaccc acggttcata agtagcttta
    47161 aaatctggct tttttgagct tctaagccaa caatagatat tttgttcata ttaactattg
    47221 ccatattatc tcactacctt tccaataacc gcttcaatag ccttactttt tctttcttca
    47281 gcagtttttt caattttcag acattcactt ttagcattag ctaagatttt atcaacctct
    47341 gctctactgt cggtgactgc cttctcaata agagtttctt ccataagctt tgcttgtttt
    47401 tttacatcag caaatatgct ttcacatttg tttacagcat cagctctgat agactctgca
    47461 tcagtaacag cttttacttt gatactgtct gctgtctgct ctgcctcaac aatgcttttt
    47521 attatttcaa aagccatcca aatcacctct cttacctttt tactatgtat ataaccaatt
    47581 agattttttt attctaatta gattactacc tcattgttaa agtataaaca gcatttttat
    47641 ataataatta atatttttca acgtttattt cttaataaaa catattttag aatagtactt
    47701 gcctagattt acatcctttt ttgacttact tttagactat gacatgagta tggtttttaa
    47761 ataccattat tttcaataat tataatttaa agcgatatag tttgtcaata gcgttatttt
    47821 gttttaaaat taacgttatg tcgacatttt aaatttttat tttatttttt ttataatttt
    47881 aatttaattt attacatata aaagtttttt atattctttt tcaacctcta accattgaag
    47941 tttattgttt tttttgaatt tttagaaata tctcgcacta ttttatctaa cttttataaa
    48001 tcatcaagct atatcgattt ttgtcacctt atttttaatc taattttttt atatctagtt
    48061 agaaataaat caatattttt aaagattgat aaaacttaca cctagttcta atagttttat
    48121 tttaaggcaa tgtattaatc ttaagtagat aatatcatta gttactctat atattcgaca
    48181 acattataaa aaaatcctcg taccaatcac tccaatcttc aataggatat gctgctcctc
    48241 catttacact tttcagtaga ttggatgtat attcttctcc catagaaaaa agttccccta
    48301 ctgtcatatc ataacctcta gatgtaacaa ccttacaaaa tgaatccata acatcacgtt
    48361 gttctcttgt ttttataagt tcttttctaa attcatcatc attcttagct tcttctaaaa
    48421 ttttagttaa tttttcattc attatgtatt tctcctttta agtagtcttt ctgtaaactt
    48481 caataagctt tatataaaaa ggaagccatc ctaaataaac taagatgact tcgcttaact
    48541 gttagcaaca catttactag tataaaataa ttggtgtacc tggttctata ttttcatata
    48601 ttttctttgc cttagaaaaa ggtgtattta cacatccatg tgaacctgaa gacttatata
    48661 tacttccacc aaaagaattt ctccaagtag catcatgaat gcctatgttc ccattaaacg
    48721 gaagccaata acttacaggt gaactgtaac cttgaccagt taatgaaaca tttctagcct
    48781 tataattaag aggatatata cctgatggtg tagcaaatcc tctagctaaa tcacctgtta
    48841 caacgtctgt tgatacaagc atttctccat ttttaaagaa ccacatatgt tggccagaaa
    48901 gactaatctc tacatatgta tttccaatat catctttatt acgagataca gctttttgta
    48961 tgtaaatagg ttctcttgta acatttttac cagcttttac aacatcaact aatgcttcag
    49021 cttctttctt tttatctatc aaccaaccat aaattccacc tgaaattgta atatctttac
    49081 ctgtggcagt tttaaatggt cttgagtcac caaaagtact gtatttttta cttaaacctc
    49141 ttgtatattc taccatagca tcattatcaa aagttatgtc ataattcttt tctgagtcta
    49201 cttttaacca tttattaatt tcagaaccat ctaaagtttc cttacggtca ctaaaatcat
    49261 atgtaacgac tacaccaaca tacttatcta atgtcttaat agcttgtttc aacttttctg
    49321 aatcctttgt gttgtttggt gcttcataaa ctttactttc atccagagaa atagaagtat
    49381 tcccagaatt aattgagttt tgtactaact tataaaaatc atcttttttc actttgtttc
    49441 caagtacctc tggtactata acataagcgt ttttagtgct atcatactta ggataagcac
    49501 tcttaggttc tacaacattt ttactatcaa aacaagataa agcattaaac cttttttcta
    49561 gtaaatcttt attatatgaa agagttatca tattattata ctctttagac ttaaatattc
    49621 caccaatcca tccaatagcg ctctgactat cttttatctt ttgaacttta tcatctggtg
    49681 taaattttaa atcaatatct tttgctttta tttgttcttt cttattgttt ctttcctcta
    49741 agtttaaagt ataggaatta gtactagatg ttaacaaatc atttacttgc tcaactgttt
    49801 ttcctgaagc ctttacgcca ttaatagtcg ttccaaagta aaaatgattt ctaaaaaaga
    49861 ttgccattcc tatataagct acaaacaaaa cacctactac tatagctatc ttaaatttta
    49921 gatttttttg tccactttct tgttttacct cttttccatc aatcataatt aaatccttcc
    49981 ttacattgta attacctatg taccttattg gtttttaaac aaaaccatgt atgccttatt
    50041 ttatataccc aaattactgt atcattattt atatttttaa atatatagtt atttctataa
    50101 aaccatttta tcttttagat aaaatgatta ttataaatcc cccctttcaa aatcccttaa
    50161 acacaatctc tgctatatta atatattacc atacttttaa taatcgtggg actatctatc
    50221 tatttttgta acactaaact actattttaa aaaagaaact aattttgtgt tagtttcttt
    50281 atcttaactt atttttatat tgaattttag cttaacataa cgttgttata tagattctat
    50341 ttaattattt tagtttctat atcttttcca tctgcatatt ctttaagtaa ttccttagca
    50401 tatccaaaat attcttcaat atcagattct tgactaaaag aaaatataca aattaatatt
    50461 tcatttgcat cttctgttat cattgctctt tcagaatcac tagttggact cccaaattta
    50521 cccactgaat cagataatat aggaagattt tctatattta ttaattcttt cccaataccc
    50581 ttatactgtt ctccttcatc tcctacagta aaacatactg gtgaatgtaa tttgcttaca
    50641 ttatatgtac ctactggata taatgatttt attgatatta aattgtttat ttctactata
    50701 ttatttattg tataaagacc cttcccttga ataattcttc taaccaatgc ttctgaagat
    50761 gttctatatc tacttggatt ttttccaagc tctttataag catttcttgc atctttaatt
    50821 ttatctagtt tcgtaatgtc ttcaactttt agactttgat ttatagtatc acaaaactca
    50881 tttatttcat taattaattt ttctgagctt ttatttactg ctacttttgc ttgaatgcaa
    50941 cccagcttag cattaggcca tctttcctta agtttgtcat caatacttat atctatcata
    51001 cttaaacaac tcctatacac taaattttta ttaaagtttt tatcatctat acattatagt
    51061 actattcttt tgttaataac atgtttatta gcaaaataaa tttattttta atataatttt
    51121 tataaaatac aattattttt tgctttatat tagacaatac attgataaaa taaaaaaaca
    51181 ctaattattt agcaatgatt tattaaaatc aagcattcat aatagtgctt tatataaaaa
    51241 tcaaattttg ttttaaagta aatctaaaaa attcttagct ggcattggtc gtgcaaaata
    51301 aaatccttga actaaatcac atccaaattg tttcattaac tcagcttgtt ctttactctc
    51361 aacaccttct ataattacaa ctaaatctag tgattttgct agagacacta ttgattttgc
    51421 tatattgcga cttctctcat catgttcaat gccaccaaga aaagacttat ctagcttcaa
    51481 tatatcaatt ggcatatctc ttaaacaact aatagaagaa tatcctgtac caaagtcatc
    51541 catagaaata gaaaatccat acgtcctcaa ctcatttaaa acattcttta aaatatttaa
    51601 ctcattaata gccacagttt ctgttatctc tatttcaatg aaatctgaac ttaaattata
    51661 catttttatt gttttattga taaattttac aatatctggt tgatacaact cgaccctaga
    51721 taaatttact gaaactggaa ctatcttttt accttgcttt ttccattcat ataaatcatt
    51781 gcaaaccctt tcaaatacaa atctcccaat ttttaaaatc aacttacttt tctctgctat
    51841 tggaataaat actgcgggac ttataaaacc atgttctgga tgattccatc ttattagtgc
    51901 ttcactccct atcatttctc cagttacaag tgaaaactta ggttgataat acacttcaaa
    51961 ttgatttttt accaatgcta tttttatatc atctaaaatc attgattcct cactaagctt
    52021 attcctaaca tcttcattat aaatagcata atttatattt ttacctttag caacagacct
    52081 agccatattt gctttattta cagccttttg aatatctact tcaccttctt caacaaaata
    52141 aatacccaca cacagagaaa tttcaaagac tatactcaaa ttactttcaa tattacttcg
    52201 tatattatca agttttctta taattttatt tcttccattt ttataatcac agaaaattgc
    52261 aaaataatca cttgaaagtc gtgcatatac ctcaccttct gttaattctt cttttaaagc
    52321 ttttgctatt gtaattaata aattgtcacc aaattcatat ccaaaagtat cattaatcat
    52381 cttaaagtta ttaatatcaa aatatactat aatataattt aaagatggtt tatctaaaag
    52441 atacttacta cattctctat aaaatttatt ttgatttcct atatatgtaa ctttatcttc
    52501 ataagccaaa cttaatattt ctttttcatt agattttttt atataaatta tataaaaaat
    52561 aattgcaata aatattaata caatagataa cactgcatat acagctctgt tgattatttg
    52621 ttttgaatta ctaaatacaa cagtttctgg aattgaaaaa attaaattcc agtcttttat
    52681 ataattattt tcactattcc cattatccat agtggcatat cctaaatatc ttctttcttc
    52741 caacatattt aatacagttg cacctgtttt attttcttgc aattcttttt ttaatctatt
    52801 tacttcttga atatcattat cctgttttaa caatttataa atattttttg ataggctatc
    52861 cccttgtgga tgaaggataa ttgtaccatt attttttaca acataagata tactattatt
    52921 ttcataaaaa gatatattaa taagtttcat cagagtattg atattgtaag tacaatataa
    52981 aactccaact actttatcat tatttaataa tggtactgaa atagcaatct tctttataga
    53041 cttatttact tcatcaacat atggacttga aacatacttc ttacctttaa ttgagttttt
    53101 gaaaaattct ctatctttca ctgaaaactt atcacctttg gtattttcag cattaccatt
    53161 tatatcaact attgccatag tgtaaaattt ttgattttcc atttcatcta aaagattttt
    53221 cattttttcc tcattaggta tatctggatt tgaagcataa tagttagaaa aaatatttaa
    53281 aacatctaaa tctttttcaa tttgtctttg tgctagttga gagccttgta ctgcaacttc
    53341 ttttatatgt atttttgcct ctgacataag aagatgtttt gtatcttcta tatagatata
    53401 ccccattgtc aaaaataatg atgttaaaaa aagaattgta attaatgtaa aacttttatt
    53461 tctccctgtc attcgactcc tcccctaatt agtcaatact tcatatagat aatatatcct
    53521 ttttatacca attcatcatt tatattgtat ataactattc ttaaatgtta cacataaaat
    53581 caacataata accataaaaa cattctttta ttattataat aacactattt aattgaattt
    53641 taaattaaag aataaaaact atccattttc tcaaacaaaa aaactcttat acaataaaac
    53701 tttgttttat gtataagagt ttttatttta tctattttat agcaaactta tcttccataa
    53761 tatgaattta aatacatatc ttttatttca ttcataagtg gatatcttgg atttgctcct
    53821 gtacattggt catcaaatgc ttgaattacc atttcatcta ttgaatccat aaacttagat
    53881 tcttcaacgc caaactcttt tatagattta ggaataccaa ctttaagttt taaatcttca
    53941 atagctacca ataaactttg gaatttctct tcatcagaat ttccttttaa tcctaaaaat
    54001 gaagctattt cagcatatct ctttaatgct tctggatatt tatattgaga gaatgctccc
    54061 attttctttg gtgcatctga agaattaaat ttcataactt ctgttatcaa aagagcattt
    54121 gcaacaccat gtggtacatg gtggaaagca cctaatttat gagccataga gtgacaaaca
    54181 cccaaaaatg catttgcaaa agccatacct gccattgtag aagcatttgc cattttttct
    54241 ctagcttctg ggtcttttgc accattatca tatgcacgtg gaagatattc aaatatactc
    54301 ttaatagctt gtaaagctaa tccatttgta taatcggttg caagcataga tacatatgct
    54361 tctaatgcat gagttaaagc atctatacca gaagcagatg ttaagctttt tggcatattc
    54421 atcatcatat cagaatcaac tatagccata tttggcatca gttcataatc tgctaatgga
    54481 tattttactc ctgtatcttg gtcagttata acagcaaatg gtgttacttc tgaaccagta
    54541 cctgctgatg ttggtatagc tacaaaatta gctttttcac ccattttagg gaatgtatat
    54601 accctttttc ttatatccat aaatctcata gctaggtctt ggaaatctac atctggatgc
    54661 tcatacaatg tccacattat ctttcctgca tccattgcac ttcctccacc tatagatatt
    54721 attacatctg gattaaattc tctcatagct ttagcgccta tcttagcaca ttccaaagtt
    54781 gggtctggtt ctacttcaaa gaatgtagtg tacttaatat tcatttcatc taataaatca
    54841 gtaactgctt tagtatatcc attattgtaa aggaatgtat ctgttacaat aaaagctctc
    54901 ttcttattca ttacatcttt aagttctttt aatgctactc ctaaacaacc ttttttgaaa
    54961 taaacttttt ctggtgctct aaaccaaagc atattttctc tcctctcagc tactgtttta
    55021 atattaagta aatgcttaac tcctacattt tcagatactg aatttccacc ccaagaccca
    55081 catcctaaag taagagaagg agctagttta aaattatata agtcccctat accaccttga
    55141 gaagaaggag tattaattaa aattctacaa gttttcatgg ctgaagtaaa cttatcaagt
    55201 ttttctcttt gatttacatc atcaatatat aatgaagatg tatgcccaaa tccaccatct
    55261 tctactaatt tttctgcttt tctaactgca tcatcaaaat cacttgcctt gtacattgca
    55321 agtactggtg aaagtttctc atgagcaaaa gcttcttcta tttcaactga ttctacttca
    55381 cctattaaaa ccttagtatc tactgggact tcaaagcctg caagttttgc tatagtacaa
    55441 gctgtttgcc caactatttt agaatttaat cctccattta ctaaaattat atttcttatt
    55501 ttttctgttt catctttatc taataaataa gcaccacgct ctttaaattc ttttttgact
    55561 tcattgtata tattttctaa tactataacc gattgttcag aagcacatat cataccattg
    55621 tcaaaagtct tagatacaag aattgagttt acagcagttt ttatatctgc actatcatca
    55681 attattgctg gagtattacc tgcaccaact ccaatagctg gttttccaga tgaatatgct
    55741 gatttaacca ttccaggacc tcctgtagca agggtcaaat ccacttcttt cataacagtt
    55801 gtagttaatt ctaaagatgg ctcatctatc catcctatta taccttcagg agctccagct
    55861 aaaacagcag cctcaagaac aacttttgca gcctctatag tagaattttt tgctcttgga
    55921 tgtggagaga aaattattcc atttctagtt tttaaagcta aaagtgcttt aaagatagca
    55981 gtagaagttg gattagttgt aggtacaact gctgcaataa cacctattgg ttcagcaatt
    56041 ttagtcatac caaatgcttc gtctttctct ataacaccac aagttttagt ttctttatat
    56101 gcattatata tatactctga ggcataatga ttctttataa ccttatcttc agcaattccc
    56161 ataccagttt ctttttgtgc cattatagct agaggaactc tttgcttatt agctgccaaa
    56221 gatgctgcta aaaaaatttt atctacctgc tcttgactat atgtagcaaa tattttttga
    56281 gcttctctga tttttgctag ttttttaact aagctttcaa cgttatttac agtatctaaa
    56341 ccaactgaca taacttcatt ttctttttta ttttctatta ttacttgttc tttatgagcc
    56401 attttaacaa cctcctgaga tagtttttta tttattatgt taatttatta acattatagc
    56461 atttactttt cctattttca agttattttt ttaacatttt attttttatc taatataaca
    56521 tcatttctac taataatatc tagctttaca aatacttaat ttaactagat atcactttat
    56581 tttttacgca aatcactaat gaaatcatct aaaaacttaa ggataacgtt atttttttaa
    56641 cgtttatatt tttgtatttt ttgcaaataa aactttataa aaagaatttt taatatgata
    56701 ctctatcaag tttaaaaata aaaatccttg aaaatgaaaa ttaaaactta attaacaagt
    56761 taaagtaaat atagttaaat gtacaaacat ttacaacata tagtataatt aaaaaaatat
    56821 atattcatga tttttatata atatgaaata aaatatattt aatattatat agataaattt
    56881 gaagtttata agaaggagga taagcatgga aaaattaaaa acaattagcg ttttttcttt
    56941 gattataagt gtaattttaa cgattggagg tattggaata gtaacttatt atgtagataa
    57001 tttgtttatt agaggactat cagtatttgt tttaattatg tcctcttctt ttgtatcaac
    57061 aacagttaga ttgatatttg aagagtcaaa acgatataaa ttctaattta aaaattggat
    57121 taagtaaata attttaatat agcaaaaatt acggagatta gctcaaaata gactttttag
    57181 tccatgaggc atttttttgt atgaaattaa atatattttc atcatttcaa caagaaaaag
    57241 aggcttctct ctattttgag acagcctctt tgctagtatt gtatctaata cataatatta
    57301 taagaaccaa ttctattgat gtggactttt tataacaggc tgtagctgtt tgttctctag
    57361 agcaagttct atagttggaa ttattagctc agtatgtgca atcatagaat taggctttgc
    57421 tttgcaatta tcttgaccaa aaggtacaaa atatatattt ttagaattaa ggagaatgcc
    57481 aatatttttg aaattaaagc ttagagcatc attcgttgat attgatatta ctagtggttt
    57541 atcattacga agatgacctt ttgctgccat taatactggt gaatctgtaa taccatttgc
    57601 taattttgca gcagtatttc cagtacaagg agctattatt ataatatcag caattccttt
    57661 aggtccaaat ggctctgcct cttcaatcgt aactataggt ttatttcctg taagttcata
    57721 tgcttttttc ataaactctt cagaatttcc aaatctacaa tcgatatttt gtgatacatc
    57781 tgaaaatata gtgtgtacat tagctccttc tttaaccaaa ttctctaact ctataaatat
    57841 tttatcataa gtacaaaacg aaccagtaaa tcctactcca attgtaagtc cttcaagtct
    57901 catttctaat cccttctttc atttataata ttttctatag cgttaacaag aatttcacca
    57961 gatgtctttg gtgaatattt accaggaagc ccaaggcaaa gagtcgcatt aatccctgct
    58021 tctttaacaa cagaataatc tactcctcca ggagaagaag ctatatctat aatagttact
    58081 tcttgtgata ctttttctaa cctttctttc gttaaaatac actctggtat ggtgttaaaa
    58141 atataatcaa attgtaaaag tttttcatca agttgactta aagaaatact ggaatatcca
    58201 aatgcattag ccgtacttct tgcatcatta tttcttgcgc caacacatac atttgcatcc
    58261 aaagcgtata atttttttgc aagtatttgt gcacatcttc cataacctaa tactaaacag
    58321 ttactttgat gtatattgat tatacttctt ttaatagctt ctgctatagc cccttcagct
    58381 gtagcaactg catttaaaat agcaacatca ttcattttca taaaatcata aatctgaata
    58441 gagtgttgct cgcaaaattt acaaacttta gttggtatgt tacctccaaa taatatttga
    58501 ttaggagata aattaattag caagttatca atagtagcat caagacaatc atccgtattt
    58561 tcaatattaa cttgattctt tgtaaatgga attggacata aaataatgga acttttggat
    58621 agtgcttcag ctagtgaagt tgattttcca acgattccat ttataatttc atttgatatc
    58681 ccataagtga ctacagaata ccctttatta attagttttt ttaccatgta cacttgtcgc
    58741 aggtctcccc caataacagt tatatcgtat tgatttgaca tattgtaagc ctcctttact
    58801 atatacaata tgtttttatc aatacattgg ttcactaaaa ttactaaata ttatacttat
    58861 aacattttta ataatgctaa tctatctatc ttttcagaag aggtatatgg aaatgaattt
    58921 aaaaagataa ttttctttgg gatttcattt ttcattagat tatctttcat tttaatcaac
    58981 aaatctttct tcgtaatttt gtctatagtt attacaaata atacaatttg atttcctctt
    59041 atagtgtctg agtacggcaa tacaattgca tcttcaattt gaggaatttt tttaacttca
    59101 ttttcaatct tagtagaact aactttaaat cctccaatat ttataatgtc atcacttctt
    59161 ccttcaaata ttaagtatcc atcattatca taatatccaa tatcattgac agaataaggt
    59221 ttggttgcat tatatactgc atattctgta ttcacaaaaa tttttccttc tctaatatat
    59281 atatctattc ctggaaatgg tctgcctaca cttagaggtt tttcaattag ttcatcatag
    59341 cataaatatg taatataatt taattcactt gccccatagt ataaaataat ttcagacttt
    59401 ggcatatatt tttttagatt tcttgcagta tcttcaaata ataattgaga ccctgtaaaa
    59461 atacttacaa ctttgagtac tggttctttt aaatgtttaa ccaaaagttg aagttttgta
    59521 ggtataaggt atatgttagt tacattatat tgttttattg tccttatcca tgatttacaa
    59581 ttaagacctg aacttattac aatactacct ccttcatata atactgacat tatagaattt
    59641 agattccctg taaaactaag tgttccatta acaaacaaga ttgattcccc agagatatta
    59701 aaaataccat tttgtatagg aaaaaatcca gcccaactct catatgttct atataatacc
    59761 tttggaacac ttgtagaacc tgaagataaa gctcccatac aaatactttt atctaaataa
    59821 tttataagct tcttatattg atacatatat atattaaatt taggattaaa aatagaaaaa
    59881 ttaacttttt ttgctacttc attattgtta tcatcatata aatcaataac gtccatagat
    59941 tcatcagata taatgattga aatattattt tttaataaaa tatcatctaa tactttttta
    60001 gaaagattat aatgacaaat aataggaata ttttttgaat aattaatagc aaaaaaacta
    60061 atcaactgaa acattatatt tttagaatat attaaaattg ggatattttc acctaaagaa
    60121 atttgctttc ctagttcctc actataactc aatatatttt cataagtata tttttctcca
    60181 tctataatta aaaaattttt atttttttgc ctctcttttt ttattcttaa aagttcataa
    60241 tagttcataa tctacaccct ttcaagcagt aaagctgaac ctagaccacc agctgcagct
    60301 atagagcaaa ttccatatct acccttagtc ttttccaatg cttttaaaag atgtaatgca
    60361 ataattgcac ctgaagcacc atatggatgt ccatacgcta aagctccacc aaatatatta
    60421 tatctatcta ttaactctgg atactttctt tgaaacaaca catctataac tgcaaatgct
    60481 tcattaaatt caacagcaga tacatctaaa taattaagac tttctatctc taaaagttta
    60541 tccattgctt gtatcgctga tgttggactt aaggttgcat ctgttcctat tgtgcatgta
    60601 ttaataattt ttgctttagg cttctttttt acatgttcta aatacttctt agaacatatt
    60661 ataataaatg aagctccatc attaataaga catgaatttg ctgcatttgt aatagtttct
    60721 tttcctaaaa ttgatggcat cctatctaat aacctttgac tcatcttatc acgtatacct
    60781 tcatcatagg tactattatt tataggagat ataatatcct caagtatttt ttcttctctt
    60841 gcttcttttg ctcttttatg actttccttt acccaaaaat ccaagtctgc tttctcaatt
    60901 tgatatagct ctgctactct ttccgcccct tcgagcatac tattttggct attatcatca
    60961 ggagaaaatt gagcaactgt ataatttgga ttatttgtat catatcgctt atcattctta
    61021 tgatatgtgc gcattggttg tagagaacta ctttcaaaac cacctgcaat aattaaatca
    61081 cactgaccag atttaacctt tgaaaaagct atgtctatac tcatcatagc agaagcacac
    61141 tgcatatcca cagtaaaagc aggtacttca tttgacactc ctgctgttaa agtcattaat
    61201 ctagctatat tccctcctgt cccaactgca tttccacata taatctcatc aattttgtca
    61261 atttcatact ttttaattaa atcttttaaa acacttgctc ctagtaattc aggttgaaca
    61321 aattgaaaaa ttccattttt tagacctata tgacttctca atcctcctaa tataaaaact
    61381 tccttcatac attacaccct tccttatatt atagatttat catagatttc ttctgagtac
    61441 attgttcagt ttagtgccta aaaaagatgc aataactgac tttattgtat ctccaattaa
    61501 aaatggtact actgctgcaa aaagtgctgc ttctactgtc atttgattaa aatagcacat
    61561 aaatactgtt cccataaaat atataatagg cattccaaca aaaattgtta ttagtatata
    61621 tctcttaata tcattgtttc gtccttttaa taaactaata attagtgctg caaacaaaaa
    61681 cccaaaataa aaaccacctg ttgggcttaa caactttcca ataccagatg tacctccacc
    61741 aaatactgga atcccaatta aacctatcat tatatataca ccaactgtac taaatgcttg
    61801 tcttggtgtt aaaatcaaag ctattaaatt tatcattatt gtttgtgctg ttactcctgc
    61861 tggagtaaat ggcaatggta tatatatgta agatgatata cacaataatg ctacacatat
    61921 tgacatttta gttaaatctt gaatatttac tttagtattt ttcattttta taattccctt
    61981 catatgtctt atttcattta gtttatatgt acatatacaa agcttctatt aaagctttgt
    62041 tttagtataa aataaagacg tttttttgtc aactattata attatttagg tttacattta
    62101 atttataagt aaactttata ctgttacttt atattttaat agtcatttat aaaactttgc
    62161 ttaaaaacag ctctatttag actatacttg taaattataa tatgatatat ttttatataa
    62221 gattttattt tatataaaaa atagtaacaa atagtttata cacaagatat ttaaaaggaa
    62281 gtgatgatat gaaagttaat gaaaataata taaataatat agatgaagag ttaggtgaac
    62341 ttagtaggaa agtttactta gagtccccag atttttggat aagtatttct gacaaaataa
    62401 tagataaagt atttgatgaa atgttattat tttttgcagt taaatataac tatttcaata
    62461 tagtatgctt tgctattgaa aacaattatc tggatttaaa catgccttca aaaaacaaaa
    62521 aatacactaa tataatggag catttgttag atacatcaaa gcagaatgaa gataaaaaaa
    62581 tttataatta tcttctaagc ttaaataaag gtaataacct agatgaaaga ccaattttag
    62641 atgaattaaa ctgtaatatt agtagtgata cttttgaaaa aaaagatata tatcttccaa
    62701 agtacttatg tccaagttgt aattctaata tatttgatac aggttataaa gtatcaaatg
    62761 acataacata taaattttct tctaaagaag ctgaacctat tgaaatgtgt agtgaagttt
    62821 cttctatcag atgttgtaat tgtgatgaat tattagaaga tattacactt gataaactat
    62881 ataacctatg caaaattcaa aactgtaata attgtggttc taatttaact aaggtaggaa
    62941 ttattgcaaa gaaaaaaatg aactttgatg agaatactga aaaatttaaa gatgtctcaa
    63001 catcttactg ttgtggaaat tgtgactctg aaataagctt atctcaaaga gaacatttta
    63061 agatttaaat atttataggc taaagtaata agattacatt attagatact gtataagttt
    63121 tttaaatctg taaaaataaa tacacttata agaattaaaa ttgctatgaa actagttctt
    63181 gatgaactaa tttcatggca attttctata atctaataat tattaaattt taacaaacct
    63241 ttattagcat tccataatta tttaaaattc tttcaaatac cctatagttt ataggtgaaa
    63301 gtatctttaa tattatatca aacttattat ctttaaatag taaatttgtt aaatctgaaa
    63361 tacaccatac aattttattt tcctcttttg tagctatatc aattctgatt aacttacatc
    63421 tataataaat atctttatct tcatatagtc tattttaaaa attactctta aaaaatcaaa
    63481 tggcaaataa attaattatc cttttaatag aatgtaatca tattatttac tatattccat
    63541 tatgtactct ttaaatcctg aatcttcatt tacttgttct tttactatat taaaaccttt
    63601 tttattataa aacacaactg cttttttatt atctttatat actgctaagc ttagactttt
    63661 atatttttta gttgcataat ctaaaagttt acctccgata cctagatttt ggtatttggg
    63721 ctttataaat aaagctccta taaagctttt atctattatg cttataaatc cttttatttc
    63781 atctccatca tcatatacaa atgtatctga tataggtata tattcgtttt taacagtatt
    63841 atagttattt tgccagtatt ctttacttat aaagtcatgt gctttgattg tacttttttc
    63901 ccatatttcc atgattttat ttatgtcttt attgtttaat ttctttatca taaattttat
    63961 ttcacctcat ttttgtattg attttataat gtttataggt aagtgtattt tatttagata
    64021 tgatttagtt aatataaggt ggatgtttta gtatatgcta ttgttgattc tacaatttta
    64081 tatactgctt tattaatata aaataagttt ctaaatactc gttgatattg ctaatattct
    64141 acttatctac ccttagttga tataaaacct gacactgtgc cttgtgtgag tcttttcttt
    64201 atcctattta cataccactt agttaatata aaacacttcg aaattgcagt tttcagcatg
    64261 ttattgcgca atttacatac cacttagtta atataaaaca caaacaagag tagttgcaat
    64321 agcactaaaa atttcattta cataccactt agttaatata aaactttgca ttatattagt
    64381 taacttttcc catattttcc catttacata ccacttagtt aatataaaac atataaatgc
    64441 tagagaaatg gtagtcgtaa atgacaaatt tacataccac ttagttaata taaaactgaa
    64501 ctcaatattt tccacgttca tgaaaagttc ttatttacat accacttagt taatataaaa
    64561 ttgattttgc tggtaacgtt atagatggat ttagagaatt tacataccac ttagttaata
    64621 taaaaccatt tgtaaatctt tatgattatg taatatattc ataatttaca taccacttag
    64681 ttaatataaa acgtgtagca aaaagtaaac tgggttgtaa ttatgtgtaa tttacatacc
    64741 acttagttaa tataaaacaa cttctcacat tccagataat tgttatttta ctcgatttac
    64801 ataccactta gttaatataa aacttttata gcttgccact taaaagaaga accttgtctt
    64861 atttacatac cacttagtta atataaaacg aaaaggattt aaagcaggaa gtactagcta
    64921 tacaacattt acataccact tagttaatat aaaactgaac ttagaaatag aagaaaaaga
    64981 aaatttatat aatttacata ccacttagtt aatataaaac acaataaatc ttgtctcgta
    65041 ctcattacaa tcttttattt acataccact tagttaatat aaaacaagat agatacaaaa
    65101 tgatgcaggt tacaggtatg catttacata ccacttagtt aatataaaac ttttttggta
    65161 tagtagatag aatgataaaa atacactatt tacataccac ttagttaata taaaacatgt
    65221 tagaagatgc aattgcggaa gtggcttggt cttatttaca taccacttag ttaatataaa
    65281 actaaataaa aatgaagtag ggggtatttt atggaaagat ttacatacca cttagttaat
    65341 ataaaacctt tttgttgttg gttttgttgt tggtttttct tgttatttac ataccactta
    65401 gttaatataa aactgttgca tggttagggg ctggaggggt tccctaggca atttacatac
    65461 cacttagtta atataaaacc cacgcatttt agttcaaatt cgtagctttt ggcttattta
    65521 cataccactt agttaatata aaaccagcaa catgaatttt cctagcataa tcttttaaaa
    65581 gttcatttac ataccactta gttaatataa aacgtttgtg tgtcctcact gttccagcat
    65641 tagggggcta tttacatacc acttagttaa tataaaactt agtgcatctg taacactcat
    65701 gtccccaaaa gccccattta cataccactt agttaatata aaactataaa tgctttgatg
    65761 ctatttttga caagttttcc aatttacata ccacttagtt aatataaaac cccaaaatag
    65821 gtatatttga atacattgaa aacacttcaa tcaagcaatt ataattcaat aaaaacatca
    65881 aaatttgcag tgagcgagca gtagtgcaat tgataacagt tatcatacac cttcaatccc
    65941 ttatattcca actgttaaca cctattttag cataaatatc gctcactgca aacctatata
    66001 aacatttcat cagaatactt atcaatccca taacatttct ttttaattga attaggattt
    66061 tttatctcat aaacatagat tgaatcctcg ctattatcaa taatattttc tatttcagaa
    66121 atacatttat gtaactttcc ttcagtaata ttgccttcaa aaacagaatt ttgtgtccaa
    66181 gtcaaatatt ttctaagtat ccttctaatt ctatttaacg accttgcttc aacaatatca
    66241 taagtaacaa taacaaacat acttaccacc acacctttaa aactttgtac ctttcatcat
    66301 ttataaaatg tttaattaat ttataacact ctaaccttat aaacattcta tatgaaactt
    66361 ttctatttag atttctatgt tttatagttg tctgcatctt attttcaaat tcttgcaaaa
    66421 atttcttctt tcctttttca cttaaataac aaattttgtc ttgatattca aaatcattct
    66481 tattaattct tttattatta atcaggctaa aaattattgt gtcaactata attggcttaa
    66541 aaatttctgc aatatctaaa cttaaagaaa atctctttgt tgatggttca tgtaaaaagc
    66601 ttattgtagg gtcaagttgt gtcttatata tctcacttaa aacattcgta tacattatgc
    66661 tatttccaaa agacataaga gcatttactg ggtctttggg aggtcttttt tctcttttat
    66721 aaaattcaaa atcatctttt aatatttgat taaatgattt atagtatgtt tttcttattc
    66781 tgccttcttt acccataagt tctgatattt ctttgacatc attcaaatca tttagttcat
    66841 cctttatagt atcaattaaa ctttcatcaa ctttgtaata tctcatattt cttaaaatat
    66901 ggtatgatgc actttccaca aaggattttg ctaagtataa tctttcattt ttatctaaat
    66961 agcaggctga ttgacatact aaactgaatc ctgatacatt tttcttcctt ggataatatg
    67021 tacctgaata atatccatag taattgtaga aatgaagcat caccccatat ttacttatgt
    67081 aatttataag ttttgtgttt aaatctactt ctccatatat atgaatatca tcaacttgtt
    67141 ctactggtaa tatttttttc tcaccttcta aattgtaata gtaaatcgta ttttctttcc
    67201 tttttatatc cccattactt ataatataat agtctttata cattgttact cctccttcac
    67261 aaaacaaaat tcataataag cacattttgt acaataatgt tttttctcaa ttttggaagg
    67321 agataactgc atatttattt catttatatt tataagtgtg ttttcaataa ttctttcttt
    67381 ttcttctgtc aatatcaatt cttcttgttt cttttcctta acataattta tagttccttt
    67441 tttctctata cccatactat tctttaaata gtataagtaa tagtataact gcatttcatc
    67501 tgcttctttc atctttgaac ttatttttac ttcttttaca tactcatcct ttattatatc
    67561 tagcttcaag atatcatcaa tcaatatttc tttatttttc attcttttat atgaatcttc
    67621 atgtactatc ttcccagaca atactctact actattttgt tccatggtta ttcctttaga
    67681 aaatagccat agttttcttt tacatacata ataataattt atttttacac cttgaacttt
    67741 taatacttct aaatctattg gcacaaaatc accttcttta gtaaatttta gccacattgt
    67801 taatataaaa atcaaataaa ttggtctatt tcattactta taagcacacc tttaccaaat
    67861 atctgttttg tatgcttatt ttcgtatata tcatatttat ataaaagtat ttttaaatct
    67921 tcaagacctt tcacctgtat gtcaattaca ttttgtttag ctttatatat tggtaaattt
    67981 acagtttttt taattatctc tcttcttgct ttttttctct tagactttat tttatttatc
    68041 aattgtctat catcattact atatgcattt ataagctctt gtcccaactc ttcataatct
    68101 ttgattaaag tttcttcaat tttattatat atatcctctg gaattactgt atatccttca
    68161 atatttctaa gtatattttg tgcatcttta gaacctaaac tatatggcgt tatagtatct
    68221 aaaatattta aagcactggt aaatctcttt tcaaaagctg taccttctag actttcttta
    68281 gagtatagta tcttaaccat ttctacctta tatttttctt tcatcttcac acattctttt
    68341 ccatttataa aagttttcag tagctcaagt cctttttcta caatatcctt atcataaata
    68401 ctacctattc ctgtagcttt ttctgtatat ataaatatat ttgggctatt ttcttcatac
    68461 tcacgacttc tataacatct accaaatcgt tgaaatagac tgtcaagtgt tgaattttct
    68521 gtatgaagct catcaaaatc aatatcaaga gatgcctcta ctaattgtgt tgtaatccaa
    68581 attccatttc tatcactatt ggcaaattct tttatatatt tttctaattt tgctctatct
    68641 tcttgtatat acatagaatg taaaagattt aagttgacat ctattccttt tggtttaact
    68701 atttcttcta ttaactcata tttttctaca gcacttttaa ctgtatttac tattacaaga
    68761 acttttttat tcattccact ttgtattatt ttacctaagt tttcatctat tgaattttct
    68821 acaatagaaa cacaatgtct tattttttct gtattacatg tcaattcagc taagttacta
    68881 ttcattacac ctcttttttt taattcatct atatatatgg ttggcatagt agctgtcatt
    68941 atcataaatc tgccacctat cttatgtatc atttctatac cttttaccaa tacagctgct
    69001 atttctggtg aatatgcttg tatctcatct attactactt ttgaatatgc taatgttgag
    69061 tacacttttt cataccctct atacaaaaaa ggaaatttaa atatttggtc tattgtagaa
    69121 aatgtcagtt tgcaagataa taactttgct aaatctacaa tctcacttga attttcttga
    69181 ttactttctt ctagataatc tattgctgtt gaatgtaaca aacctaagaa tgtatcattt
    69241 gattctccaa ctccaactat attttttgct ctatcaaata atgcatttat acttactctt
    69301 aatggaagtg taaaaaatgc cttgtcttta tctatccaaa ttaaggcagt ttctgttttt
    69361 cccattcctg tagatgcaat cagtattata ttcttatttc tattagattt agcaaatgat
    69421 tgagcctctc tcaaactacc aaactctttc attaaataat tttctgtctg ttctcctata
    69481 tttataacat tattgcattc cacaacttca tgagcagaag cactatggtc tagtctatgt
    69541 agtattcctt ttaacataat atataaatta tagtacttgt gatttttatc tattcttttt
    69601 tctacacttt gtagatatac tttactcaat ctttctgttt ttattggata tctaacttta
    69661 aattcatgct gtagttcata aactttattt attaaatctt catctaatat tttttgtatt
    69721 aaatttttaa aatctttatc tataaagata tctctttcat gatgatatac aataacttga
    69781 tttaatactg ctctaagttc tttatttttt ttcctgtcta tataactata atcaataaat
    69841 gcaggagaaa gataattatg gcctacatta ttttctaaat gagttactat tttaggttca
    69901 tttattttag tatccattct gctttttatt aactcttgaa acggtgaaaa tgcctttcca
    69961 atatcatgaa attctataac aaggtcaagt aattgccaaa atatctcctc ttctagaaaa
    70021 tctaagctat ttatattttt tccataactt tctcttaata cattcatttg ttttaaaagt
    70081 tcatcagtat gttctctaag tgtttccact ggattagatt tagcatataa cataatctcc
    70141 ctcctaattt atattattaa aatataataa atctccttca ttatctaata atatatctcc
    70201 aattgatata gtatttccat cctcaacata ataactatct accttattcc aaaccctttt
    70261 tttatcttcc acagcattat tatcatagta attattgagt ctgtaactta taccatctat
    70321 atctgtatct tgtaaacttg tttttggtat atatataggc attcttatat tacattctga
    70381 taacttataa ttttcataat catctaattg tatatcctca tctacttcaa atttattgac
    70441 ttctacaaat ctaatatcat taattcttac taaatcttct tttctaccta atgataagtg
    70501 ctcgtcataa tttaataaac tatcatatat ttcttccaat aaatcaaaat ccccacctat
    70561 atgaattatc aaatttacat tcaatagcat atgactattc attggcatag atgtaatact
    70621 atctttttta taaaaatatg ttgtctggta attattaaat atactttcat atgttccctg
    70681 tacacttata ttaaatggta tatattctgt agcatttaat attttgtgaa ttaatccatt
    70741 tattgtagaa tatggaggca gtggatatgt ctctgtaatc ttcatagcaa atggtttttt
    70801 gtagcatgca gtttcttgaa ataaatctaa tttcaaaacc ttcatattaa ttcaccccat
    70861 aatattcctt tacttcttta actagttgtc caaaaaattt atctacacta aaaaaattat
    70921 cttcaaacaa tcccttaaat tcttctttat ttataaatac cccatctacc attccaacat
    70981 aggtaaattc ttttaaatct tttcctaaaa aagtaccttg gattacttct tctatagctt
    71041 gtttatttat tttaaatcca tttttatctc cttttaattt aattctaccc aagaaaaatg
    71101 gatttgctat ttcatatact cctcctacta caaatagagg agataaattt tcttgtctac
    71161 ctctaatatt tctattcaat acttttatta tttctaaaaa ttctactact cttctacatt
    71221 tctctttatt atcaagttct atctctccat ccttgcctat tttagataaa tctatagtca
    71281 ctgtatatgt atagtaactt aaatgttgct ctatgttagc aagattaggg tgttctccta
    71341 ttctatctgc aaatccttta ttatttaaaa aatccatatc acttctatat ggctcaagag
    71401 aaatcgcatt acttaatctt acagtagctt ctctagtcaa agaacctcct tttttatctt
    71461 tctcatcttt tttatttgtt ttcatatatc caaataaatc catttcttct gattctctta
    71521 tacttatatt atctttaaat tgaatagtac ctttttcttt atcgacaacc tgtaaattcc
    71581 aattaaacaa ttctgctgct aatcgtacta tgtcatatct taaacactgg cgagatgcaa
    71641 atgtatatat atttccatca tctctactta atttttttaa ttctgatata ttacctatcc
    71701 cttcaccata gtttaaactt tgagcttgtg ctattactgt aaatgttaac cctcttttca
    71761 tcttattttt cctccttttc gtttggtagt ttatcttttc cttcatattt cccagaaatt
    71821 aatccagata taaaagcatg acctatagat tcaaagtcta aatctttttc aatttctata
    71881 tctaaaataa atgctggcat ctgtttttca gctgacataa aaactcttat aattgtatcc
    71941 ataaaatcac ttttatttcc gactttaact gaatttaaaa gtttatagct tactccacct
    72001 attttatttt tagaattttt attaacaaaa tagtcatgta tatcacaacc taaataataa
    72061 attattctca gcttttcatc attcttctcc aaatttttac tatccatttt atataccccc
    72121 tttttgtagc tatttattaa tgctcttaat tggactactc taaaacaatc tattcctgat
    72181 atatttgatt tgttgttgct ttccatatca tttttaactt tatttcttaa aatgttatta
    72241 attagatgct tcaagtccct atttttcaag agtaaatcta gtacatttga tttaagcttg
    72301 taatcataga tactttgtat ttttttattt gcatacttat ctgtaaaaaa ttttgctaaa
    72361 taagttggaa tattaaaata atttatttta cattttttag aatctatact tgctttaaat
    72421 tccacaaaaa gtatattacg aagttgccat tcacttttca atgtattttc ttctactata
    72481 ctttttataa gctgattaaa aggattttcc tctttggaat ctgaatactc acttttttga
    72541 gcttttaaac tattatttct ttcaaaaagc tcatttatac aagtatccat gttaacaaat
    72601 aaataaaact cattttcttc attaattaaa taattctttc ttgtataagt agcccctgct
    72661 ggagtacaga acaatattag cttacaaata tcacatattg atggtacata cgcctgattc
    72721 caaaacatat tcctagcatt attggtgctt actccaagtg gagcaaaatt actttctgag
    72781 tattcatcta atattccctt atataaacca cacatttcac atacttctaa actatccata
    72841 tactttttta tatcttctat gcttttattt ttctttataa agtttttatt tatttccttc
    72901 ataatttttt ctatagtatt tatactagac ttactaactt ttttttcatt tatatcctta
    72961 gctatactat ttaatctatc atttaaatag tttttcaact tatcatagtc attctcttct
    73021 aataaatctt ctaactctcc aaaatatata atttgtctta aataatcatt aaacattacc
    73081 tgttttaatc catctaaatc taatttcgcc ttagcaacat taaaaaaact aacttgtcca
    73141 aaataattat cttgaactac atatttataa agatttgctg taagcctgtc atttattgat
    73201 tttattttaa atatatctat agtctcatct actaaagctt ctaaactgtc aaattcatca
    73261 taacttttta tcttagacat actatctagc ttctctttta tcaggttaaa tttttcttca
    73321 tcaaattttt taatcttatc attttgttgt ttcacactat ctttaatttt cttaattcca
    73381 tctttgattc tatcaggctt agatttaata aaatttatac tataatcaat atttttttta
    73441 attctttttg atacatcata ttcatccata aagtaattaa aataatactc atgaaagttt
    73501 tcaagaaata agctatcaaa ttcgatataa tcttccataa taaatatttc agcttgttta
    73561 tctgctttct ttattatatt taaaaatcca actataccca tattaaaaaa ccaatctcct
    73621 ctataaactc ttaacttcat ttatctcacc tccattctaa aatatctaca tctccaaatc
    73681 cctgagcacg tctaaaacca attcctagat tgtagataag atttaaatca tcaatatcac
    73741 ctttcaatat aaatttacct ttgtaaccat taatatattg atactcttta cctgttattt
    73801 ttttaaattc tcttaaactc tctttaacta ctaccttttt gagacctata ttttcaaatt
    73861 ctaactttct ttttaatcca ttccccctat aatttttaac cacttcatta gttatatagt
    73921 ttagttcttc tatgtatcta tcatcagtta tctccaagaa ttttccttct ttagacttta
    73981 cacaaattgg agacaatgca ttaaatagta ccctttcttc tgttaccttc ttttctcttg
    74041 ataaatcgat tctaattctt gtaagttcat agtctttata taaacatttt ttagaagtca
    74101 ttaacccatt gtatatatga aaacccaatt ctaaatctgg agtacttata tttaatatta
    74161 ctttatcttc tataataaaa ttgtcacctt caatactata cttttttata taaaccgaaa
    74221 atgtaaaatt tttagttttt ttattattct tttctttata atagtacatg tttttatagt
    74281 aatcttcatt agattttctt attgcttctt ttataatact cataaagagc gaattataag
    74341 atattggtat acaacctgta ctaaattcaa ttttcatttt cataatatca cctctctcaa
    74401 ttaatatatt aacactagac cgtgaagtat attggtccaa gtataaatta tttgaaaaaa
    74461 tcagtaaatt tttttcattt tttcaatctc taacaatata tcatttctaa gtctatctgg
    74521 ttctacaacc tcaacataag ctcccatact taaaatccaa ctttttatct cctcataacc
    74581 tctcatttta gctttaaaca ttatagattt atcatcatat tctatgattt gttgattatt
    74641 aacccaaact ttttccttta taattgttga aaatggatga ctaattttta taacaacact
    74701 aatttcttct cccttataaa ttcctatact atttttacta tattcatccc aactaaaact
    74761 tttatctaca ttatattttt cttctaaaac cttataatct ttaattctac ataatttaaa
    74821 gtctataaac ttaaatcttt tttcacaaaa agctaccata taagtatctg atttataatt
    74881 aaataaacca tatggatgaa caattctttc actatttcct gaatttaatg aataatattc
    74941 tatccaaaat ttgtgttttg tggtatatgc tctaattatt tcattacact tatttttttc
    75001 agactcataa tcacaattac attgtgcttg aactgtaaaa taatccatat atgtatcgct
    75061 tttttctcct gtatttaata ctgcttttat tttttctaca atattattaa attcattttt
    75121 gtaaatatca ttattatact ctaactgtga atttatcata tctagaattg aaacttcact
    75181 atctaataat ttaattaatg agatgctatt acatttatct atttcataac caccataaat
    75241 cccaggtgtt gaatttataa atataccagc ttgctctaaa tacatcttgt aactttttat
    75301 ttgcctttca cttacttcca actcttctga taattctttg catttcattt tgcctctgct
    75361 ttgaattaat atcatcattc taagtgtatt agctaattta ctaatgagta acccccccta
    75421 ataacattaa ttgatatttt tattatttat ttctacacat atgtacatat aacctcttta
    75481 tattttatat aagtagaatt tttttataat tttgacattt accatattat attttatatt
    75541 tgtacaaaat tttaatagtt aatacaataa aaaatattac tgaaaaaata aacatctata
    75601 attccagtaa tattaattaa ttctaaaccc tttttattat catttaataa tagtaactaa
    75661 aaattgacta aatttaacct tatctctttt aaataattat ttcttacaat taaaaaataa
    75721 actatttgaa ccaagaacaa gcttcccatt accaaaacag ctgatgatgc tacttctata
    75781 tcaaaagaat ttttaagtgc agtaagtgca aatattgaat gtataacagc cactacataa
    75841 ggaaacaaaa atactattcc aatctcaatt gttgaagctt ttttaatctc attatatgtc
    75901 atacccaatt tatttaactg ttcatacttt ttcttatcaa cttggcaatc catataaaat
    75961 ttattatata aaaaactact tgtagtaaca aagaaaatta aacctataaa tattgctaaa
    76021 aatataaatg tagaatacat taatttccca gttcctatca ttaattcttt agagaaaaac
    76081 aaatatggtt gcatccctga ctcattatta aatttatttt caaattttct gcatatctct
    76141 atagttttac ttgaatcctc tacttcaaat gcagtaaatc tatccactat aaattttgat
    76201 tctatactat cataaaaatt atcctttacc acatacatat ttttgtaata tgctggcata
    76261 acacattctt ccacttgttt tgccaccttt aaacctctat tccctacaat aatattttct
    76321 ttgatgttct tatttcctgg taaacttgat gataataatg atatacattc attatcttca
    76381 aaacttatag gcttaacccc tatagtttct gtaatttcta agtacttaga ttctttcata
    76441 attctgacat taaaatcact tttcttggga aatacagttt taaattcacc attagtcctt
    76501 gtatagtcta cattctcttt ttttagatta ttttctataa acatcattct ttccttgtct
    76561 ttttctttgc tatcaggctt tttagggtca ttatgcaatg tcattgttga ataatatatt
    76621 gtgttaggat atattaaatt aatttgacgc tctacatctt tccaaaagga ataaactgta
    76681 cctatagcag taaatgctac tgcagaagtt atagttatca agaaaaatat tctagcatta
    76741 tcctttacct tataaatcaa gttcgaaatc caaagcatat ttgtattttt tctataaaat
    76801 ctcttgttta attttagctt cttcataaaa aatacactaa attgagaaaa gaacaagtaa
    76861 gttgctacta tagtaaggga tgtaactgga actaagcgca gatatgttgt atattggtcg
    76921 gttgaggtaa tagcattata atacgctatt ataaacaaac aaatacttaa tatagcaagc
    76981 attagtgatg ttttaggctc tggttttgga gtttttgtac ctttaagtaa cttcaacacc
    77041 tgattttctt taactataaa agaagtaaat attgatgtta atacagctaa aatcataaaa
    77101 tagattaaag tagacaatat cgcattaaat ggtatataga attttaatgg tgataattct
    77161 aaaaaagtag acataaccac taaaaatatc tttgcaaaga ttaagcctat tattattcca
    77221 attacagaag atactatatt tattatcata ttttctataa agattaattt cattacttgg
    77281 cgttttgata tacctgtaat ataaagtatt ccaaattctt tatatctact tttaagaaac
    77341 acactaactg aataaaacac aaagaagaat aagaatagat atgcaattat cttactcatc
    77401 ttgagacctt cttttaaata atcaggaaat tgagatacat ctaaatctgg atgacttgta
    77461 aacataataa aagaaaatag cagtgaagat gatataacaa tacttgctaa gtatcctaaa
    77521 tacgctttaa tatttcttga aatattgtta atagcaaact gttttatatt cattagttat
    77581 cgcctcccaa taatgtaagt acatccatta tctcttgata aaactgctct ctactactac
    77641 ccttatatat ttcattatat atagacccat cttttatgaa taagattcta ctacagtagc
    77701 tcgctgctaa tgggtcatga gttaccatca tagtagtaac tttattttct ttatttatct
    77761 tttgaaatag ctccattaca acctttgatg actttgaatc taaattacct gttggttcat
    77821 ctgctaaaag tattgatgga ttgttaatca atgctctagc aatagcagtc ctctgagctt
    77881 gaccacctga tacttcaaaa gttctttttc ctaataaatc ttttatacct aatattgtag
    77941 atacttcatt caatctctca tcttgctctt ttacactgac cttatctaat gtcaatggca
    78001 atactatatt ttctcctata gttaatgtat ccaataaatt aaaatcctga aatacaaaac
    78061 ctaactctct tcttctaaat aatgcaagtt cctcacctct taacaataaa ggattcttgc
    78121 cctttaattc catagttcct gtagttggct tgtcaatagt agaaatcata tttaaaagag
    78181 tagtttttcc actaccagat ggacccataa ttcctacaaa ttctccatct tctatactaa
    78241 aatttatgtc atttaatgcg ttgaaaatta tttttttacc atatacttta cttaaattat
    78301 ttacagttaa aattttcatt atttaactat ccttcctaat ttaatttttg aaataacata
    78361 tatataattg ttaattataa tttatcttag tttaattttt atagataata aatctatttt
    78421 ttctatacac taattatgtt agtaaaagct aatactgcaa gtactacacc catgattatt
    78481 ctgtatacag caaacactct cattggtttt ttctttaaaa aattcacgaa tttttccata
    78541 actattattg atacaataaa agctactata aacccaacta ccaaagcaat ccacaatgtt
    78601 ggtgtcatta ttgaataatc aaattcaaat aaatcttttc ctgaagaagc caccatagct
    78661 ggtactgcta aaaagaaaga aaactcagct gctgtaggag aattaagtcc tgctatccat
    78721 ccacccataa tagtagatgc actccttgac atacctggcc atgcagacaa aacttgtaat
    78781 gtcccaacct ttaaagcttg tattggagta attttatcta tattatctgt ggaatgattc
    78841 ttttttctaa acaaagtttc tactactaat aataaaatcc cacccactat aaatcctata
    78901 attacagatt gtaaattaaa caatgatttt atattatcgt aaaatagaac tcctataatc
    78961 gcaaatggta tacaacctat aattacattc attccaaatc taaaaccaat ctttccttct
    79021 tttccgccag taaatataaa tttaaaaaat tctataacgc tatcttttat ctttttccaa
    79081 taaagtacta ctactgctaa tatagcccca agttgtatta caacctcaaa catttcagca
    79141 aattgcccct taaaatctat taaattacca accaaaatca tatgacctgt agatgaaact
    79201 ggaataaatt ctgtaagccc ctctactata gctattatga ctgatttcaa tataaaaata
    79261 acatctaaac tcatcaataa acatccttcc ttttttacaa aatttctttt tttatgttat
    79321 ttctcttatg ttatttctta tattaattgt aatttagatt agaaaattta actatctgca
    79381 aacattacac aaaccttaca tctatgtaag gtttgcaaat aaactctctt aaattttgat
    79441 tatttaacta tgaatatttc atttaataaa ttgtataata aaaaagtaca attaactaaa
    79501 aaccctattg taacagataa tttacacctt tattaaacta tttacatctt tattaaagta
    79561 gattgaaact tctgtacctt ttcctacttc tgattttata cttactttat gacctaaatc
    79621 atcacatacc ttttttacta gataaagacc catacctgta gattctccaa acttacgacc
    79681 attttctcct gtaaaaaatg ggtcaaatac cctttttaaa tctttagaaa caattccaat
    79741 tccttcatct attatactta aaattacata tttattattt tcttcagatt ttatagttag
    79801 gtagttacta taatctttag aatatttcac tccatttgta attaattgac ctattataaa
    79861 tttcatccat tttacatctg tataaacata agtaaatttg tctacttgaa tcttaggaat
    79921 cattccactt tttataaata accttttttc ttcatttaca atactagata caatttcatt
    79981 taatttggct ttttcaacta taaagtcttt ctgaaaatta tctgcccttg caaaatgcat
    80041 agccatatct aaccctttat ttaatctatc tatttctttt cttatatttt cagttacttc
    80101 ttctccctca taatcttgaa gctgaaggct tataactgat attggtgttt tcatctgatg
    80161 aatccattgg ttgatgaaag ttaaatgttc actatgtatc tttttatgct cttgtatcat
    80221 tgattgatac aatttatgtt gttgttttaa aataactgat atatttctcc ccaagaatga
    80281 gcttcctaaa tacaaaaatg actcctccaa agaatgtact cctttttcaa acagattata
    80341 tacttctcta tttttataat acttatatat taaaaaacat aacaatataa aagaactaaa
    80401 taaaagaata tataaactct ctccaaaact aataaacttc ataagattac agtaaataat
    80461 tgtcataact atgcctatat aatatataaa aatataacct ttataatctt ttaaaaataa
    80521 cttcatactt tctccttacc aattcttatt taatttatat cctaaccctc ggacagtctg
    80581 aacagcatta tctataccta attcctcaaa tcttttcctt atcctgctaa catttacatt
    80641 taaagtattt tcctctacaa actcaatatc atcccatatc ttttctaaaa gataatctct
    80701 acttactact tttgggtatc tcttgataag acattcaatc agtatacctt cttttttagt
    80761 tataattaga ttctcaccat ttaattctag ttctaacctt tctggataaa actttaatcc
    80821 atctagctcc actattcttt cgtctatttt aggtgaatat tcaccatata cccttcttat
    80881 atgactcttt atttttgcca ttactacatc atagtaaaaa ggttttgtta tataatcatc
    80941 tgctccactt tctaaagctc taatttggtc tacattacca tctctagctg atataaaaat
    81001 tataggtaaa ttcgactgtt gcctaataca tctacaccag tagaaaccat caaatttagg
    81061 taaatttaca tctaatagaa ctaagtgtgg cttaaaactt tcaaatgtaa tcattatatc
    81121 atcaaagttc tcttcaacaa tcacttcaaa tccatatttc tcaatataat ctttaagtaa
    81181 tgtacttatt gatatatcat cttccacaat atatacttta taactcatat aattcctcct
    81241 aatataccta tttactcatc atataacagt ccaattttaa tatattataa tctttttgca
    81301 atatataaat ttaatcatat tactaacttc acaattactg acttcataag tataaccata
    81361 ttattagaca tcttaataaa actctataaa aaagtatctt tttatgatta attaatcatt
    81421 attatcaact aatcattcta aaataaattg aaattactaa ttcaaaatag aaaaagttac
    81481 cttaataagg taacttaaac ttttattata tttcttactt agtattattt tatcatagtt
    81541 tctacttagc attatagatt aattctttta tgttcacttt tttctcttgt aacttatttt
    81601 ttattaagaa gtcttgtgta tcttcaagcg aagatatgtc tttatctgtt atatctaaac
    81661 taaaatcata ccaagcatat aattctttag tttcttcaag acttaaatca acttctttag
    81721 ctactttttc catagcttca tcaaaattat tatttacata ttctaaagtt tccttttcaa
    81781 ccttcataaa tctttcaact atttctggat gtttctctgc aaagtctgtg ctaacagcag
    81841 ttactattat accatctact aaaccttcac catttgctac aagtttacta cctgacttca
    81901 tagctttaag agctgctgga ccagcaatca atgcagcatc tacgctgcca tcagaaagag
    81961 ctgctgatgc ctctggaata cccatattaa caaattccac atcatccata cttaatcctt
    82021 ctttatcaag tgctgaaatc aatacctgat gtaatatagt cccttttggg cctgccacct
    82081 tcttacctac taaatctgct gctgatttta ttgaattatt attagtcaaa atcataaatc
    82141 cttttggtga cctgctataa gtgtttaata tctttaactc tactccatta gatgcagcta
    82201 ttaaagctga tgtaccacct agtgcatgta agaagtctat ttctccagca gctaaagctt
    82261 gtgtttgctc tggacctgta gtaatttcgt ggaagttaac ttttatatta tcctttttaa
    82321 attcctttcc aaataaatca tcctgtttct gaattataga aggaacattt aatggtgatt
    82381 ttacataagt taaatttatt tctgaaagtt tttctccatt atttttttta gcacatccag
    82441 ctaaagatgc tgttgcaagt gttaatatcg ttatacctat caatagcttt tttaatttca
    82501 tttactttac tccttaaaat attattaatt tctttaaatg cctttatttg atttcattgt
    82561 cattaaaata tcttttttta atttaatata gtaatctgaa gttaaatctc tattataacc
    82621 atcttctata ttaaattctt ttatttttct ttcgtctgtg aaaacaacta ttttcttgcc
    82681 tatctttaac gcttcatcaa tatcatgagt tacaaatatc acgcctttat tagttgactt
    82741 atgtattctt ataacttcat tttgcatatc aatccttgta aaataatcta atgccgaaaa
    82801 aggctcgtcc ataagcaaca tatctggatt gaaagaaaga gctctagcta tgcttactct
    82861 ctgtgccata cctcctgaca attcatttgg ataagagttt ttaaatttct gcaagttcat
    82921 catcttaaga tatttttcta catcaatatt acttttccta ttatatttat ttgatttgtt
    82981 caaattatca tttgtttcta agcttctaaa attatcattt ataattttac tgctaattct
    83041 tttattgtgt ttaaattttc taagcacctt gtttaaaata gtattttttc tttgattatg
    83101 aaaagctata ttttcactta cgtttaacca aggcattaat ctgctctcct gaaaaacaaa
    83161 accaacatta ggtctatact ctttattatc attaataaac ctaatttcac cactatttat
    83221 accttcaagt gatgcaattg ctctaagcaa ggtagtcttt ccacaaccac tttcacctaa
    83281 aattactgtt atatggtttc tatctatgtt taaagagata tcactaagaa ctacatgttc
    83341 ttcattgtca actttataac ttttatataa atttctaatt atatatccag agtcacatac
    83401 taaattattc atatgcttcc accatctttc ccttacttac cttcttcaca ataatcgaaa
    83461 atatgtaatc tgtaattatt cctaaaagtc caattacgat tatacctaca ataacaacat
    83521 ctgttctaga catttctttt ccatcagata tcaagtatcc aagaccagat gaagctgcta
    83581 caagttctgc cccaataatt gctctaaagc tatatccaag agctaacttt aacccaacag
    83641 caatatcaag aatggcattt ggtattatta ttttaaatat tatctgaagc tttgaaaact
    83701 caaatactct acccacttca atcagttttg agtcacaatt tttaatccct ttcaatgtgc
    83761 ttgtaaagat tgggaaaaag gatgctaaaa ctataattat aatttttgat tcctctccta
    83821 taccaaacca taatataagc attggtatta aagcaagggg aggtgtattc cttaaaaaat
    83881 ttattagaga tttaaagtat tcgtatactc cactataaat tccaaagaat atccctaaag
    83941 gcacacctat agcagtactt attgcaaaac ctatcaaaac tcttttcata cttgcatata
    84001 cattaataaa tattgaacca tcacttatca tatttaaaaa tgtactatat accttttcgg
    84061 gtgatggtaa tatataatca ctccaaatac caagataatt tgtaattttc cataataaaa
    84121 gaattataaa aaatatcaga acactcttta ctagccttaa aaacttatta ttaaatttat
    84181 tgaccattta caaaccatct ccattattac aaccatcttt acaataaaac atttctacta
    84241 tgtcatactt atcttcaaaa ccatttctta ttttttgtat ttcacttaat atttcgtctt
    84301 cacttgatac ttcaagaact ttttcaaaag tatctttgaa atatcctaat ggaattggtg
    84361 attcatctat ttttccaagt gattttacac cttcttgttc agcaaactct ttccatgtat
    84421 aaaacatagc attaccctta tccttaaact tttcacttgc aaagtctctt aattgtgtac
    84481 atggacaggt tactaccaac atatcatctt tactttttat atatttatcg tataaaaccc
    84541 tacaagtcct tactaatatt ggttctatca taggtacttc aaaatcattt atcaaattat
    84601 ttctttttaa aagacttata ctttctggac atctacaatc caacattgta tttttagtct
    84661 tttttgtata ctctttgtac tgctttttta catattctaa ctgtggttca cattctgcta
    84721 ttatgtaccc cttttttatc aaatttgctt taataaggtg aaacttttct ccatacattc
    84781 tttctgccac tggatttatt agaagatatt tattcataac gcctcctatt atttaatatt
    84841 gaatattatt atcaattaat agtttaaatg agcacttaaa ttttgtcaac atattaattt
    84901 tttcttaata aaacaatttt tatctacatt ttttaatatt ttaaatgaaa tattaaatag
    84961 tatatgtaat ttattttaat taataatgca tacatcttac taataatcta cttatataat
    85021 aatctataaa tattatataa taatacttat ataattagta ttattattta atagcaacag
    85081 ttattcacac taataaaagt agaaagtttt taaaatatta tgaaacatca aatttaattt
    85141 taaaattgca tcaaaaaatg aagtctcaac agacttcact ttttataact cttataaatt
    85201 attcaaaata tttatacttc cctttctact tcaaaacgta aaaccgtctt caatgattca
    85261 ggcgatactt ttctagcatc acttatataa atttcacgat gtgtgtaaga ttttcttata
    85321 agtttatttt ctttgcaaaa ttcgttcata atgtcaaagc tttctggttc attatcatat
    85381 gaacctatat gaagcttttg aacacatagc ccttcattaa tagacccaaa tctaactttt
    85441 tcaagaagat tatgaggttt tttcttcttt actatatcag tagctttatc caacaggtct
    85501 tgtgtaacaa aatctggctg acgtatcatt atagtgtaaa ttaaatcttc tttaataagt
    85561 acatctaagc ctttactttt ttctccctta tcccatatac cttctaaagg aaaaaccgta
    85621 tagtcaaaat acccttctgg tacaattcct tttttaggca tggtttttat tgcatatgcc
    85681 aaagaataaa gtactcctat tgcttcagta aattctttag aatttgggtc tccactccct
    85741 tttaacatga taaatttctg ttctggtatt tcaactatta caggattctt tttaggtaaa
    85801 tataactctt tatctctttt tctccattca tatttcataa aaatacctcc atatatattt
    85861 tatacattga tattatcacg ctaaaagtga caacagtgtg tcataattat aaattatatt
    85921 ataaaatctt catcctctaa ttcctcatac actccttttt ggtatccatt acccttagtt
    85981 gaaaagaaat catgtgtttt ggtttcagtg ctaagaccat ttaatacaat tggatttata
    86041 gcatctacag tatatagctt ctcaaaccct agattttcta aagctctatt cgcattgtat
    86101 tttaaaaagt ttacaacctc tttttcaagc ccactttctc tgtatataac atttgtatac
    86161 tctatctcat tctccataag gctataaagt atagaataca tcttctcttc taacatctcc
    86221 ttatccattt tatcaaatga atcgtatatt tcttgtgcta gcaatcctat atacttacca
    86281 tgtaaagact catctctaag aataagcgat attatttctc cactagctac catctttcct
    86341 tgaccagata gatacaatgg ataaaagaat cctgaataaa acaagaaact ctctaaaaat
    86401 acacttgtaa ccattgatag gtataatccc tcttgatttg tagtattttc gtattgagct
    86461 aaaactaaat cagcctttct ttgtaatgtt ggttctgttt ctatccattc aaataattca
    86521 tctatttcta aattagaaag tagagtcata aatatagaag aataactttt tgcatgtatt
    86581 tcttccatag tccccataaa agacaagaca gcttttcttt gtaggttttc tgttaaactc
    86641 atcatagatg gtattccatt attcccctgt tttgtatcca gtaatgttaa accacccaat
    86701 acttttttat ataattcctt ttctttatta cttagttcat tccatacctt tatgtcttta
    86761 gaaacagata tttcttcagg aagccaaaat tgttttacat tttgttccca aaaagcttgt
    86821 gtaaatccat cttcttctct attccagtta actgcattat gtattttatg taaattaaat
    86881 gtcatatatt tctctcccta tactgaacac actagacact catgagtatc tcttgtcatc
    86941 tttgttcttg tgtaatataa acttttcaaa ccttttttat atgcatatat gtaatgtcta
    87001 gctatatctc tagttgtctt ttcatctgta acaaacagtg ttgttgatat accttggtca
    87061 acatggtttt gaactgttgc cactaaatct atgacctttc tcatatccat cctgtatgct
    87121 gattgataat acaacatatt atcatttgtt aaaaatggca ttggatatat tgtagtagag
    87181 tctccatatg ttcttacttc tactggctca gtaattggca ttatacttga tgtagcattt
    87241 tgaacataac taatgctttg agttggtgct actgccatta aatatgcatt atatatccct
    87301 ttttctttta cctcatccaa taattttgtc cagtcttctt ttgttggtat ataaatccct
    87361 tcaaataatg ctcttacctt ttctgactta ggtagataag attgttcata gtattttgat
    87421 aaaaccttgc tatttcttcc cttaacatat tctgatttat caaatccttc aaaagtttga
    87481 tttctttcta tagctatttt catagaagct ttaattgaat agtatctaac cattgcaaaa
    87541 aatacattag aaaaatctat agcatcatct gaagtatata aaatattttc tcttactaag
    87601 tatccatgta aattcatagc tcctaatcct atagaatgag acttgctgtt actattgctt
    87661 accgttggta ctggttttat atctgtgcta tctgctacaa atgacagtgc tcttattgct
    87721 gtttcaactg tactttctat agttttatta tccattacat tggctatgtt taaagaacct
    87781 aggttacaac ttatatcttg tccccattca ttttttcctc catacccctc tatttctgaa
    87841 ggtgtttgat attgaaatat ctcacaacat aagttagaca ttttaataat tccaacatct
    87901 tttaatgtat gttctctatt agctgtatct atgtacacta catatggata tccactttct
    87961 tgttgcatct gtgctatttt tgtcaacatc tgcctaggat ttatttcttt ttttcttata
    88021 tcactatcat taaccaattt atcataccac tcatccattt ctatctcatc aagagaaact
    88081 ccatatttct tatacacagt atgaggataa aatgcatatg ctacttcatt tttttctgcc
    88141 aactccataa atttatctgg tattatagct cctaatgata atgtagcaag ccttattttt
    88201 tcatctgcat ttatcttttt agtatccatc aacaattcaa aatcaggatg gaatacagta
    88261 aggtacaccg caccagaacc ttgtctagct cccatttgat taaagtaact aaatgattgt
    88321 tctaacattt tagctactcc aacaacacct ccagctgcac cttctatatc tttgatagat
    88381 tcgccagatg ctctaagttt agataaattt agtgcaactc ctccaccaat ctttgataag
    88441 tgatttgatg aagatatagc atacgatata ccttctgtac tatcttctac agatagtaaa
    88501 aaacatgata ccatttctcc agcccttttt cttccagcat ttaaaaaagt aggtgtagct
    88561 ggttgaaatt cttgttttac tattttatct gccaagttta aagctaaatc tttattgcca
    88621 tttcctagtg tcaaagctac aattaacact ttatcattat atgtttctaa tatttccttt
    88681 ccatcattgc tctttaatgc ataattttga taaaacttat ttgcactcat atatgattga
    88741 aattcaaact tatgtttatc aatcatatca tatatatttt tgataacatc tatgctatac
    88801 tgatttatta cttcttttga ataataacct tcatctatta aatacttcaa tctttcttct
    88861 aggttattaa attttttcaa ctttggctgt ataaattctt ctatgtaact acttaaggct
    88921 tccttatcct tttccaattg gtacttgcct tgttcatttt taattatcac ttgattgtta
    88981 agctctatcc aattcattat ttaccgtcct tttaacataa tcttgtgcca taatttcact
    89041 taatttgctt attatttctt ttggtactta tcagttgaaa tcccaaaatt aatctataat
    89101 tatagaaatg caataagtat ttttcaaaaa caaaagcact acatatagtc agtgctttat
    89161 ctattatata ctacatatag tatatacaca aattttttta tatctaaact tttattactt
    89221 tataattgac attattttta tttaaagaaa tttttatcaa ctcaaatata aaacaataca
    89281 agcttattat gtcctgttta aaaatttaaa ttatctctaa atagcttaaa aatatattct
    89341 gatatattga aaaaagtact ttcaagatga tattttatat attatttaga agttttttat
    89401 ttattgttat ataattaaat atatgactat tttgctacta catatataaa aataaattta
    89461 tgaaggtgat tttaatgaaa actatttcta aacaagaatt agaaaaaaca cttgagaaac
    89521 attatttatg gcttaaaaac aataatgctg gagaaaaggc agatttaaaa gaattaagat
    89581 tagaaaatat ggacttaaga ggatactgct taagtaatat tgacttttcg tggtctgacc
    89641 ttatcaattt aaatttagaa aaagcagatt tagaaaactc tatttttaat aattcttatc
    89701 tttcggattg ttcattaaaa aattctatat taaaaaatgc agacttaagt ggtgcaagtt
    89761 ttagattttg tgacttatct aactcagata ttagaggagc taatttagaa aattcaaatt
    89821 tagaacatgc tactttaaat ggagtaatat cagatgaaag tacccgtttt tttaaattgt
    89881 attgtcctga aacaggagca tttataggct ataaaaaatg ttttaatttt agaatggtac
    89941 aattattaat acccagcgac gcaaaaagag tgtctgctac atcaaatgct tgtagatgtg
    90001 ataaggcaaa agtactgtca attactagta tagatggtaa agaatctttt aaaagtgctc
    90061 gtgcatatgc tgatgaaaat tttatatata gagtaggaga aacgattgta gctgaagatt
    90121 ttaatgaaaa tagatggaaa gaatcgacta cagggattca ctttttttta actagagagg
    90181 aagctattgg ttatctataa aatgctaaag ttttataaat atataaatac ataaacaaaa
    90241 taacaaaaga gtatagatta taatttcaaa aaaattataa tctatactct tttttctata
    90301 gcacataagt acattttatt tcataaatta taataaatta tttatatctg cactattgat
    90361 tatttgagaa actttatcta tatgttctat cttattatcc aaactgtcat aatacttctt
    90421 actctcatct ctatttctaa aagaataaac ttttttatcc aattttaaag cctcttttat
    90481 aatatctata ttcctcttat ttgtctctcc tacactaaat cctgtatcta ttataatctt
    90541 ggaatcattt aaatttctaa tagccaaatc gaaactctca tcacttatag gctcaaatgg
    90601 attttctgta aacatcttta tccccatagt tctaccaatt tcataatcaa tatcattttc
    90661 atgtattatt ccagaataca gacctatacc ttttttagta aaagctctat aaattggtgt
    90721 tgctttaccc ccaccaccaa ttataaaaac ttcattttta gatttattac taatttctac
    90781 tgaacctaaa agactattaa agtttttatc atccaattca taaagcgaat ttataatatc
    90841 ctcatctact acatcttcag gctgaccata agctatgact ttattatttt ttataagagc
    90901 aactttatca caacttttta atgctatgtc tatttcatgc aatgaaagta ttactgatat
    90961 tgacttttct ttacttaatt ttttcagtat gtttatgagt tccaatctat gttttatatc
    91021 caagtgagtt gtaggctcat ctaatataat tatttctggt tcttgaacaa gagcccttgc
    91081 aaccaacacc ttttgttttt ctccatcact tagttcatca aaatatcttt tctttaaatg
    91141 taaggcatct acagactcca atgcttcatc taccattatt aaatctttct tagatagact
    91201 cccaaaaaat cctgtatatg gataccttcc tatattgact atatcttgta cagtcattaa
    91261 atcacctaat aatctatttg taagtactaa agccattttt tttgataatg cttttcttga
    91321 tatacaattt atgtttacac cattcaaata tatttcacct tttattggtg atataagttt
    91381 agataaggac cttaataggg tagtttttcc agctccatta cttcccaaaa gacatagtat
    91441 ttctccattt tttacttcta catttatatt acttataaca actttgttat tgtatcctac
    91501 acttaaatta ttagttttca acatgtctaa gccctatcct tccttttcac caataacatt
    91561 actacaattg gagctcctaa taaagatgtt atcgtactta ttggtaattc tactggtgat
    91621 aaaattactc ttgatattaa atcacaaaga gctgtaacta tactgcctaa aaatattact
    91681 actggtatca aaactctatt atctgatgtt ttaaatatca attttgaaat ttgtggcact
    91741 gcaagtccaa taaaccctat aggtcctgca aatgctgata ctattgctgc taatatacta
    91801 gatataaata ctatcaaaac tctaaaaaat cttatattta tgccaatact ttttgcatac
    91861 tcttctccta ataaaaaagc atttaaaggt tttattatga atacagtcat caaaagacct
    91921 aatataccaa ctattataag tatttctacc ttttcccatg taaatccaga aaaacttccc
    91981 atagaccaca tagtaaattc ttttaattta tcactatttg caaatgattg taacacattt
    92041 gttataccac tacatacata tccggtcata attcctatta ttaaaagagt tgttatattc
    92101 tttaccttat ttgcaaataa aatgactata gacattacaa ttaaagctcc tataaaagct
    92161 gctacaaata tactcattga atttacactc tcaaatccca atgtgtatcc tcccaaaatc
    92221 atgagagcta ctgataaagt agaacctgaa gatactccta atatatacgg ttcaactatt
    92281 gggtttttaa aaaatatctg taataaaata cctgatactg ctaggcatgc tccacctacc
    92341 atggttgcaa gtactctagg gattcttata ttgtatatta ttttataatg ttctgtatta
    92401 tccatacctc ttaatacaac atctattact tctttaaatt caatttttac agagccaaat
    92461 gctacacaca ctaaaaaagt aagtatcata cttataatta atactataaa tattgttgta
    92521 ttccttattc tcattttatt gataaaatcc atttgtatac tcctcttagc aaagctatat
    92581 taactaaaat ctataaaacc tatctttttg tgtcctctct gtactattta tcataattta
    92641 tataatgttt gattttttca cctgtagtac ctgggtggaa catctcaact aaatctacta
    92701 ttaattcgtc cgtcttatct actgattgat aataatctgg agcaaacacc cataggtttc
    92761 cgttttttac aacatccaaa tcagccaata caggtgcact agattttata gaatctaaat
    92821 ttggtgcata atctgaactt gatgaatata caaatatatc tgcatctttt gcaacttcat
    92881 gcaattgttc aatacttact cgcccttcat ttgaatctat tgaagcacat gcatttattc
    92941 caccagccat ttttatcata ttatccacat atgaatcttt aggagctata taagcacttc
    93001 cttcatatac agatgcccat acaactttag gtttagcttt gttttttatt tttttactta
    93061 cttcttctac cttttgtaca gttttattta gttcactagt agccatatct tctttatcat
    93121 aaaatgcagc tattaaactt gtccactcca ttcttccaaa tggattttgc tctttatact
    93181 cattgtctac aacataatta agccctaatt cttttaattt gtcaataaat tttgtatcag
    93241 cctctgataa accactactc actatagtta agtcaggatt taagtctact attttttcat
    93301 aatctggtgc taaatttgaa ccaacgtaat gtatttttcc atctttcatt aaatctttaa
    93361 tttctttaat agtccagtac tgctcttctg ttgttacggc ttttatacta tccagttcat
    93421 ctattgttct cagagaacaa gcctgtgttg tagatgctat taatacattg tccacaggcg
    93481 ttctaactat attagcattt ttatattttt caggaatttt aatcttcttt gggattaaaa
    93541 tcagttctcg attatctcca tcagttactt ttttaattcc atcttctaaa tcttcaacac
    93601 taaatccact agcatatttt aattctaatt tcttaccagt actagcttgt ttattctctt
    93661 tgtcactttt actacaccct ataagacctc ctaccataaa aattaccata gcaattaaaa
    93721 aaaactgctt taaaacattt gatttaaatt tcatctcttt cactccaata tcttattttt
    93781 tatgagtggc taaaaaactt taataagata taccttttaa agtatatctt attaaagtta
    93841 tattaaacca tctttaacaa gtataacttt ttaataaaat tatagtgaat tttgatttca
    93901 catgcaatta actacttata cacttaacta cctacgacaa cgtttgaagt ggcatcttct
    93961 ttgtcaaaat agctattgtt attagtatct ccaagctaat aggatagttc ccaacactta
    94021 cgattagcat ctgagtcact acgttggcaa actaatagaa atataacatt tatttgatga
    94081 tgctttagat acagtacaac tctatcaaat tgcctatgtt gttttatcct aatcattgat
    94141 tttaatttaa gcagttttat atacccattt ctatatgcac aatatctttt gagtaacgtg
    94201 ttgacaaact attttggtta gtagtatagc tatgatagtt aattttcttt gatagataag
    94261 tccgttacat ccaaaattct taggaaaata ttccttttat tcactgtttg tataaacctg
    94321 tacttataag ctcttaacat attatcacta ttcttcttga ttttctatgt attgttccaa
    94381 atcttccaat gttgcaccac cagttgttac taaacaataa cttttactcc aaaagtattc
    94441 tttccataag tatttgcgga tacttggaaa ctcattcttt atccttctgc ttgatgcaga
    94501 tttataggca tttaataact tggaaatttc tgtattaggc tttgctttga ataataagtg
    94561 aacatggtca acataatgat tccattctat caacaccacc ccataatttg gtgcaatatc
    94621 tacaaatata tcttttagtc tatcagatat agaatcatct attacttttc ttctatattt
    94681 tatacacata actaaatgat aatgcaataa gaagactgaa tgattattac tatctaattt
    94741 cattataatt acttcccttc agcttttact actaaattaa tgatataata cgtttttatg
    94801 aaaatcaagt aaaaaaaaga acctatcaat tatgcttaca ttcttaactt tcttaaataa
    94861 atacaaaaaa ctgacaacta aaaattgtca gtttttataa ctatacacta aaataaattg
    94921 taatctatag ggaatgatac ctttatgact gtaccaacat ttacttttga ttctaatatt
    94981 aaacctaaac ctaacttatt acataacttt ttacatagat ataatcctat tccagtactt
    95041 tttccaaata ctcttccatt ctctcctgta aacccttttt caaatacctt attaatatct
    95101 ctctcttcta tacctactcc attatcttct atagttaaca ctattgagtt ttctaccctt
    95161 tttgcactta tttttattaa accatctttt gactttatat attttataga atttaccaca
    95221 atttgattta atataaactc aacccatttc gagtcactat atacagtctt attaatttca
    95281 ccaagttcta attttatatt tttgtttata aagtctctat agtttctttt gataacttca
    95341 tttacaactt cttcaaggtt tagctttttt attatataat ctttatttac attatcaatt
    95401 tttgaataat ataatacttg ttccacaaaa ttttcaactt tatctagttg agtatctatc
    95461 tttttagtaa tctcattact attattttct ataataagtt tactagatgc tataggcgtt
    95521 tttatttcat gaacccaagt ttcaatatat tctttatatt cttcttgatt atcattataa
    95581 tatttaatat tttcgtgcat gtttctactt attactttta aaatatcatt tattttttct
    95641 ccagttacaa aatttacatc atcaataact tctggcaaca aatatttttt atctaaagca
    95701 tctaaaatat tatctataga attaaagtac ttcttatatt gtaaataatc aattaacata
    95761 taagtaaata atggtaaaaa ccatatacaa aataacataa atattaaaac gacatttatt
    95821 ttactataaa gcatgatacc tgatgcaatt aaaaatataa ttaaattagt acctagaaaa
    95881 acaactttat cacctatata ctctcttaat ctcatgatat tatataccct aaaccacgtc
    95941 ttgtctctat caaattttct atgcctattt catctagctt tttacgtagc cttgttatat
    96001 tgacagtaag agttctatcg tctacaaacc aatttgtgtg ccatagatac tccataaatg
    96061 aatctctaga tactattgaa ccttgattct ccactaaata agatagtatt ttaaattcat
    96121 ttttagttaa ctctatttct ttatctttat atctgagtgt tgcattaaat aaatttaatt
    96181 caataccctt aaatattaaa gtattattta cattcgaatt taatccactt ctttttaaca
    96241 atgcaacaat ccttgctaaa agtatttgtg ttttatatgg ctttgtcaca aaatcatctg
    96301 ctcctaaatt catgctcatt agttcatcca tatcagtgtt tctacttgtt acaattatta
    96361 ttggtatatt cgattcttta cgtaatactc tacatatata atatccatca tatattggca
    96421 agtttatatc aagtaatact aaattaggtt tttcacttaa tataaactct actatattat
    96481 caaattcagt aggagccata acttcatatc catacctctc taaaaagctt tttaattcat
    96541 ctctgattac ttcttcatct tccactataa ttattttttc cattaatttt tcacccttta
    96601 ttttcaaaaa atctatttac agtatgattt ttactgtaaa cagattttag ttagttgtat
    96661 taattaagct tttttataac tatattttta tacccttgat aagttgtata aaaatacact
    96721 gcatatacta acattaaaat tcctactgtc ataagtgatg aagctcctat atctggctta
    96781 ttaagccttg atataaaatt attagccact tgtattccta ctactgagtg aactaaagct
    96841 agtccaacag gtatgctaaa gtacattaga gtttgtgtaa atatagtttt acttatacta
    96901 tttttacttg ctcctagttt ttttaaggat acatatctat ctatactatc actagcctca
    96961 cttaattgct gaagtgcaag gactgccata ctacttatta aaaatactat tcctaaatag
    97021 attccaacaa atagtattgt agaagtcata ccattattat cattatacat agcatttctt
    97081 gatccacctg atacagttcc aacttcataa aaacttgtag aactatactt tgattttagc
    97141 cttttatcaa aattttcttg tgacttttca ttattatctg aagcgaagtt tatatttact
    97201 atacttgaag atatctccat gctatcacac aatttgtcat ttacaactac agtaagagca
    97261 tttgtttctg taaaatcagt tcttaaatta tcttttatta cttttttatt ttttatatta
    97321 tatgctttat tatctatttt tataatttta ttatttttca tgtattcttc tatcgaaggt
    97381 actacctctg tagcattaga tgttattaat acttcatctt ttgataaagt tattgacttt
    97441 tcacctcgta actttcttat ttcattatac tgtgaagatt ttatatatgc tacttcaaag
    97501 tccactctac cagaatattg tccttgcata acatctgaaa gtttattacc atttatatat
    97561 tcatcatagt aagcaacttt atcaccttta ttaaacttaa ttccaacctt ttcaaaagat
    97621 tcttttatat tcttcacttt acatttttca tgtacaatca tggttgcact tgcatcaaat
    97681 ggagttgcac cttttagtcc tgcatttaaa gctgatttaa aaccaaaccc tgttgatagt
    97741 attcctattg ttaaaaataa cattaaacaa ataatagata ttgatataaa gtttgtatta
    97801 atcttactat ttatttgctt tactacaaat atgtttaatc ccttaaagta aatgttctta
    97861 ttcttcttaa caatatataa tgcaaagcct gctaaactat agaagaataa tatagttcca
    97921 attacaccta atactattga cataataaac ttaggatttt taggatttaa tccaactttt
    97981 aaaaccatgc tatatgcaat aattaaggaa ataatgcata atataaatgt aattgtatat
    98041 acaaatggac ttttaaattt tatatcctct gtttttcttc ctattgttaa taaatctatt
    98101 attttatatt tagaaattat ataagtattg aatatcatca caagtaaaaa cattattcca
    98161 aaatagacaa tagttttaat aattgatgat atcgatatta caaaattgta ttcactcata
    98221 ttaaattcaa ataactttaa taataatatt gataaccctt gagatactaa taacccaagt
    98281 attagtccac ttactaaaga aactattcca actattatag tttcaaaaac taatattttc
    98341 gatattttaa ctttttccat ccctaaagtc atataaattc caagttcctt attccttttt
    98401 ttgactaaga agttattagc ataaagaatt aaactgcata aaataactga tacaaataca
    98461 gacatgtatg aaatcatatt cttaagcatt tctacatgag attttgttga agcattcatt
    98521 tccattaaag ctttttgaga ttctatagag ttaaaactat agaaaataca aattgctaat
    98581 gttaaagtca aaaaatatat gctataatcc ttaaagcttt ttctaacatt tttaattgct
    98641 attttagaat acatcgttat catctcctcc tattagagtt gttacttcaa ttattctatt
    98701 aaaaaactct tttcttgaat cagctcctct tactaattct gtaaatattt ttccgtcttt
    98761 tataaatagg attctatggg cataactagc tgtaaaagca tcatgagtta ccattaaaat
    98821 tgttgctttt aagtcttgat ttagactttc aaacctctca agtaataatc ttgctgattt
    98881 tgagtcaagt gctcctgtag gttcatctgc caaaatcaat gatggattag taactattgc
    98941 tctagctgat gctactcttt gcttttgtcc tcctgacatt tgataaggat atttatctat
    99001 cactttttct atttctaagt atgtagctac atctcttatt tttgaatcaa ttttagatgg
    99061 tttttctcct ttaattgtta atgccaatgc tatattttca taagctgtta aagtatctaa
    99121 aagattaaaa tcttggaata taaatcctaa ttcattttgt ctgaacttat ctaagttttt
    99181 agattttaat cttgtaatat cattattatt tattattatt ttacctattg ttacattgtc
    99241 tattgttgat atacagttaa gaagtgttgt cttcccacta ccacttggac ccattatccc
    99301 aacaaattct ccttcatcaa ctttaaagct tatattatct attgcttttg taatattatc
    99361 tttgtttcca taatattttt ctattttttc aacacttaat atattcttca tgttctattt
    99421 ctcctttaaa ttaattttct tatatctcta ttgtaatttt ttatttaatt tttttaaatt
    99481 gatttacatt tcattaatgt ttcatttttg tagtaattat atattattcc ctaataatta
    99541 ctaatataaa atactcaaga ccagcattct ttcttttata ctttgctaga gtaacaaaat
    99601 ttactcaatt ctagaaaaca caaaaatata gagggcaatg ccttccatct aaaatttatt
    99661 ttattctact tgtatttttc tatatattct tttaaagtca ttgatattaa acctttcttt
    99721 ccataatact ttatatcaca aaattgttgc caatcttgat atgtaaattc atttatttct
    99781 acacctttag acttggagtt taattgttta tcatctatta gattaattat gatatgattt
    99841 gtagtgttat atacagtaaa taagaaaata aagcatgata caaatgtaat catatataca
    99901 aatggatttt taaattttat atcctctgtt tttctttcca caattaataa atctatcatt
    99961 ttgtatttag aaattaaata gatattaaat atcattacaa gtaaaaatat tattccaaaa
   100021 tagacaatag ttttaataat tgctggtatt gatattacaa agctatattc actcatatta
   100081 aattcaaata actttaataa tagtattaat aacccttgag atactaataa tccaagtatt
   100141 agcccactta ccaaagagac tattccaact attatagttt caaaaactaa tattttcgac
   100201 atttcaattt ttcccattcc taaagtcata taaattccaa gtttcttatt tctttttttg
   100261 attaataagt tattaatata aagaattaaa gtacataaaa tagctgatac gaacacagat
   100321 atatatgaaa tcatattctt aaacatttct aaatcaggct tttttgaagt actcatttcc
   100381 attaaagctt tttgagattc catagagtta aaactataga aaatacaaat tactaatgtt
   100441 aaagttaaaa aatatatact ataatcctta aagctttttc taacattttt aatcgctatt
   100501 ttagaataca ttgttatcat ctcctctgat tatagctatt tcttcaatta ttctattaaa
   100561 agactctttt attgaatcag ttcgtcttgc taactctata aatatttttc tgtattttat
   100621 aaataagttt ctatgagtat aactagctat aaaagcatca ttagttagca ttaaaattgt
   100681 tgtttttaaa tcttgattta aactttcaaa actctcaagt aataatcttg atgcttttga
   100741 atcaaattta tattgttttc cctttaattg ttaatgtcaa tgctatattt tcataagctg
   100801 ttaaagtata taaaagatta aaattttgga atataaatcc taattcattt tgtctaaatt
   100861 tatctaagtt tttgaatttt aatcttgtaa tatcattatt atctattgct tttgtaatat
   100921 tatctttgtt ttcataatac ttttccattt ttcaacactt aatacatttt tcatgcctta
   100981 tttctccttt aaatttctta tatatctatt gtaattttta atttaatttt tttaaattga
   101041 tttacatttc attaatattt cacttttgta gtaattgtat attgctacct ataattacta
   101101 atataaaatg ttcaagacca acagattttc ttttgtgctt tactagaatc gtaaaattta
   101161 cccaattcta gaaaaacaca aaaaatggaa ggcaatgcct tccctctaaa atttatttta
   101221 ttctaattgt atttttctat atgttctttc aaaatcattg gtattaaatc attcttacta
   101281 tagtgctttg tatcacaaaa ttattgccaa tcttgatatg taaattcatt tatctttata
   101341 cttttaagct tgaagtctaa gtgtttatca tttattagat taattattac atgatttgta
   101401 gtagtttata tgtggctctt attgttaact tatacttatc taaaaatgtt tgtaaaactc
   101461 caagattatt tttaatagat aaaggctatt gctttaatat ttgtgctaac ttttaaacta
   101521 atctgctatc ttagtattat ttaattttta ttaacataat tgtaatttat tgttgaccac
   101581 ttttcaaagt tgatttaaca tatataaaaa gagtgtttaa aatgattata aaaatcagtt
   101641 taaacactct ttttttgctc atatatctta cttagtaagt taacatatat ttaattcatt
   101701 catcaatttt ttaatttcac atacttgttt ttcatttggt tttacaaatg gagcagtcat
   101761 ataatcactt atttgtaacc ctctgatatt catagctttt ttcattgctg gtataaatgg
   101821 attggttatt aagtaaaaat ccattgcttt attaatatat ttttgaattt ctataacctt
   101881 ctccatatct ctattattgt aagcttcagc ccatttggag caaacttctg gaattaaatt
   101941 tgataacccc cctatacaac ctgctccccc agacattaga ttatgtataa agttttcatc
   102001 ataaccacta taaaccttaa attctgggaa ctctattttc atagtattta ttaaatctct
   102061 ggtatgtccc atcaaagtta ctgtatcctt atatccaact atgtttttat gttttcttgc
   102121 aagtcttaat gtaagttctg gacttaaatc ataaccagtt ctatctggat aattgtataa
   102181 atatatttca gcctctgtat tcttagctat ttcactataa aataactcaa tactatcatc
   102241 atcaagagag aaataataag ggcttattat cataacacca tctgctccac tattatgtgc
   102301 atagtttgaa agttctatag attcatttat acacatacga cttgtaccta taaacacttt
   102361 tactctctta tttacatgac tagttactaa atctataagt tctttttgca tatccataga
   102421 catattaaag aactctccag tacttcccat tatgactagt ccatctacac ctccatctat
   102481 aagatggtca tacacttttt tattaccttc tttatctaaa tttccttctt catcaaatat
   102541 tgtaacaact ggtgtcaaaa attctgcttt cataatttaa actcctaaaa tttattttaa
   102601 tatgttcatt aatacatcag atttagcttt aatattaatt atattaaaac agttacttaa
   102661 tgtaattttt taaaattcca atactctcaa tctcacattc aactacatct ccactactca
   102721 tatatcgagg aggtgaaaat cccatcccta ctccagaagg tgttccagta gctataatgt
   102781 ctccagcctc taaggtcata ccttttgaaa gttctgaaac tatgtctgaa acgtctgata
   102841 tgaataatcc tgtattagaa ctttgtcttt cttcaccatt taccctacta catactttaa
   102901 gttttatagg aaaaggaact gcacttttat gtaaaataca tggacctaaa gaggtaaatg
   102961 tatctaatcc ttttcctcta aaccattgaa catgttcttt ttgcaacttt ctagcagaaa
   103021 tatcatttat aacagtgtaa ccaaagatat aatcttctac ctcttctttt ctaatattaa
   103081 cacctgtttt acctattact actccaagtt caacttcata gtctagttga ttatttatct
   103141 caaaatgacc atctatctca tcttctggac ctattgcctt tgtcacacgt tttgtaaaat
   103201 aaaccgtttt ttgtggttct tcaaaactat catcaaagtg agtttgagtt tcttcaagat
   103261 ggtctttata gttcactccc acacataaga tatcatgtat tggtttttct ataggaacat
   103321 gtaccgtaca tctctctctt ttaaaaacat cataattata gaatgtactt tcatttataa
   103381 tagttttcaa cttaataata tcttcactag atacattttg aattaattca tttaaatcct
   103441 taaaatttct actgagattt aaagagttaa catctataat aaataattca tctttagaaa
   103501 aaactccagt tcttttacat tcattttctc cttcagtaaa acttacaaac ttcataatct
   103561 caccctttat taaaattcta tgtatttatt ttcttactta aagattatac atagttgcat
   103621 actctagcta ttgccatttc agtatatcca agggactctg cttttgattg ttttccattt
   103681 gctacatcta caaccatatt taacaaatca tctgttaatt cttccattgt ttgtggacca
   103741 tagataactg gactagcatc aaaatccata ttatcttcca tatttgcaaa agttatttta
   103801 tttccagtta tttttattac tggtgctatt ggatttcctg atggtgttcc tcttcctgta
   103861 ctaaatacca ctatttgtgc tcctcctgct accataccag caacagatga agcatcattt
   103921 ccaggggtat ccattataac aagacctttc ttatcaattt gtttggcata atcatatact
   103981 tcacttattt gtctatgacc acctttatgt atacaaccaa gtgatttttc ttctaaactt
   104041 gttaaaccac cagctatatt tccaggagat ggattacctt ctctaacttc ttctccaacc
   104101 aattttaatg aattttcata tctatgtact atatgtaata ttttttcttt tacttcttca
   104161 tttactgctc tcctagctag tatatgctct gcacctataa attcagtagt ttcacttaaa
   104221 attgatgttg ctcctaaatc gacaagttta tcacttaatt cacctattaa tggatttgct
   104281 gctaatccac ttgttgggtc agacccacca cattcagttc ctagtataag ttcagatatt
   104341 ggaaattctt cttttctaag caaagaagct tcttgtgcca tttctctagc ataacgaaca
   104401 gctttttcta tagtttttaa agttccatgt tcttcttgta ttacaagagt ttttattggc
   104461 ttatttgttc tctcttttat tgcatcaact accaaatcat tttggcaatt ttcgcatccc
   104521 aaagatacaa ctattacacc atatacattt ggatttgctg cataaccagc cataacatcc
   104581 atagttaatt gttggtctga atgtacttgt gaacatccat tctgattatt aaaggtaact
   104641 gccccttgaa cttgtgatgc tattattcta gttgtatctg atgcacacac actcgtaggc
   104701 aatattaata tgtggtttct tataccaact cttccatctg gtcttttata tccataaaat
   104761 ttcatactga tttcctccta aaatagtcta tatactttct ataattttta tatattataa
   104821 tttttattac actcactaat caaacagcta aaaacctatt taaaaactat ttgacactaa
   104881 aagcaatgaa tacaactttt ataactctat aaatattatt ttatatatta gtcataactt
   104941 gtttatccaa atcctctcta acacttctaa cattatgaat atgtacatgt tggccacttt
   105001 ttatttcctg atttgcttct cctatatgtt caccatattt agtaacttta tcacctttgg
   105061 ccatatcttt tatagccaat ttatgataaa tagttatatc atctagtgct gtaatcgttt
   105121 ttactgtttt gtcttttaat ttaaaactaa tttcactacc tttagctatt gcttcaatag
   105181 ctactgcaac attatctttt tcatcaatta tcactgcatt tatcattatt cttgctctcc
   105241 tttataaata atataatttt attaatatcc taaaatctaa ttaaagaatt tattatttta
   105301 ccaacaactc actgtaatat aaattaagct gttattgtac catcctcatt ttgttttggg
   105361 aacttaggac atccatactt cttagcccac caactagtta taagaggtac taatattgca
   105421 gtgacaacta ctgcggctgc cacttgtgtt gtagctgttg caacatatgg ttgccatgat
   105481 gggtcaacta atgcaacagc agcaggtaca gcaattgcat ttccagcagt tgtagctaca
   105541 gcccatcctg catatcctgg acgttttcct ataaatttat cacagaatac tataaatata
   105601 cctcctacaa atacagatat taatccaagt aatactcctg ataaacctcc ttttagtata
   105661 cttgcaagat ttatgctact accaagtgca aaccctacaa aaggtacgag taaattacac
   105721 cctggctcta aaaactcttt catttttttg tcaaaatttc ctattatcat accaacaagt
   105781 attggcacta ttgcagccaa taatgacaac aatggtacat ttgcaagacc tgaagtccca
   105841 agagctatta atgtaaaaaa tggtccatca tttaaagtaa gtaaactcat agttgcacaa
   105901 tctgtttcat ctccatatga agtcatcaat gaaagatata tactaccatt actatttgta
   105961 actgcactta taacagccaa tgttgtcaga ccaaggacac catccattcc aaatagcttt
   106021 cctataagta tacctatcaa agcacctata gcaaatttag aaccaagaag tataccacct
   106081 ctctttaaaa cttttggcat ttctctaaat tgaagctgag ttcccaagca taccagttga
   106141 accccaatta tagttgcaga cccaacactt gaaaatactg ctgtcgtaaa cgaacctatt
   106201 tgtacaatat ctgggcaaaa ggtattaatg aaagctgcta taaacattgg cactatcatc
   106261 atacctgcag gaattttttt aataaaatcc attatcataa agttaatcct cctaaaacat
   106321 gatatttaat tactcttatt aagtttttag ctttaattct aacggccgtt tcggttcgta
   106381 tttaagaact aagtttttaa ttacgaatct ttgaattaat gatagcattt tcctatttat
   106441 gagtcaataa aaaaaataaa tttttgtcaa aattttttca aactttctga taataccttg
   106501 tatattatca aatgacttcc ttatatgcaa aaatacagcg tatttaaaat tatatagtat
   106561 tcaaaactat aaagttttta tacagtgtaa aaaatagata aaatataagt tcataatatt
   106621 ttgatattta catataaaaa taactattgc atatatttac ttaaattata taactaaata
   106681 tcacttactt tctttaggta tattttggaa attagttatt ccttaatgta cagtctaaaa
   106741 aaatatctat ctgtatctaa atcaagagct tatttatata taaatttaca tatttatttt
   106801 ctacattgta aaatatcgta tagtgtgcta aaatcaacat attctaatac tttaaattaa
   106861 taaaaagagg gggaaattta tgacttcaga taatcatcgc ccaacagcta ggatattaga
   106921 tattttagaa gcattagcag aatccgaaaa tggatatact cttacagaaa tagcagatgt
   106981 tatcaatgct ccaaaaagta gcatctttcc tatagttcat acacttaatg ctagaaaata
   107041 cattactatt gataaaaaca catccaaata ttctataggg atacgttctt acacattagg
   107101 gtcttcattt tttgaaaaaa gaactatttt taactatata attgacgaaa tgactaatat
   107161 agttaattcc tgttctgaaa cttgtcagct tggtatactt gacaataatg aagttcttta
   107221 tattggaaaa gtagattctc cagaaccgat tagacttatt tcttatgttg gaaaaaaaat
   107281 acctgctaat tgtacaggtc ttggaaaagc tcttttatgt gattttgaca aggaaaaact
   107341 aataagctta tatccagatg gtctaaaagg ttttacagaa aaatcaatta cagattttga
   107401 tgttttatac gaccagcttc ttgaagttca aagaacacaa atagcttcag agtgtgagga
   107461 atcaatggaa cacctaaaat gtcttgccgt accaataaga aaaaatggat gtataagagc
   107521 tgctgttagt gtaacactgc ctttatttag agctaatgac gaaaaaatag aactgataaa
   107581 aaaattactc ttaaatgctc agaaaaatat tcaatcaatg atggaagaac gtaatgaaga
   107641 cattgtaata aattagatta atattcttta tatggaagat atcaaaacat aataattaaa
   107701 aattttgttt taaactaatg tatttatttg atttatacta taaaacaaag ttgctgattt
   107761 aactacagta actttgtttt ttttataata ttttttatat ttttattgac atgataaaaa
   107821 tactatgtta aattctaatc ataatcgtaa ttacgaatta agttcttata taagaaccag
   107881 caaccctatc tcaatctaag atacgatata ttatgagtaa attagtgaaa attgttagat
   107941 atatattttt acataaaaat caatgaaaat aaaaggagat tttagttatg agcatttatt
   108001 atgtaccacc aataaattta cttgggaaag gatgtcttaa tgaagctaaa gattcaatta
   108061 aatcattagg aactaaaaaa gcatttattg ttagtgataa atttctagtt tcaaatggta
   108121 ctgtaaaaaa agtaacagat attttatctc agatagatat agactttgtt gtttatgatg
   108181 aagttaaaca aaatccaact gtaactaatg tgaataaagg acttaaaata ttaaaatcag
   108241 aaaattgcga cttcgttata actataggag gtggttctcc acaagactgt ggtaaagcta
   108301 tctctatatt agccactaat ggaggagata ttagagacta tgaaggtatc aacaaaactt
   108361 ctaaaaaatg tcttcctatc atagctataa ctactactgc tggtacatct gctgaagtta
   108421 caataaacta tgttataact gatgaagaca gacatgtaaa gatgataatg gttgatacca
   108481 attcactagc cacaatgaca gtaaatgacc cagaattaat gattagcaaa ccatctaatt
   108541 taacagcagc aactggtatg gatgcactaa ctcatgctat agaagctgta gtagctaatg
   108601 gtgcttatga tgttacagat tcaactgcct tatatgctat aaagcagata tttaaatacc
   108661 ttccaagagc tgttaaaaat ggtaatgaca tagaagctag agaacaaatg tgttatgctt
   108721 gttttttaaa tggaattgcc tttagtaatg caggtcttgg aaatgtacat gctatggctc
   108781 atcaattagg aggtttatat gatttacctc atggagtatg taatgccatg ctacttccaa
   108841 tagttgagga ggaaaatgct aaatcagccc ctgccaaatt ccgaccaata gctgaagtta
   108901 ttggaatgga tgtaaataat aaatcagata aagagtgtgt tgactttgta atagataaga
   108961 taaaagctct ttctgaagag gttggaatcc caaaatcttt aaaggatgta ggtgttgata
   109021 atcctaattt tgaattgctt gcagaaaact ctatgaaaga tgcttgtgct ggtgctaatc
   109081 ctgttttctt tgataaagat aagattatag aattgtttat gaaaatatct taattatgta
   109141 tatttataag agagtgcctc aaaatatctt tgttttgtta atagcactct cttattacac
   109201 tttttaaata gtactcttta tgagaagtta atatataatc ctattaattt aagaatcatt
   109261 atcccaataa aaaactcaaa atttttctta atgaattata actgttgttg tatctggtat
   109321 attatcatat atccactttg cattttccgt acttaatctt atacatccat gactaagagc
   109381 ttcaccaagt ctgccatcta ttatataact tcctgttgaa tcatatagca cagaatgata
   109441 gtaatatcca cctttaattc tagtagcata tttaactgaa tactcatccg ttccaaaaga
   109501 aggttttctt ccacttatat aaaatatacc tgttatagtt ggagtctcag gcttacctat
   109561 agtacattgc cacttgtaaa gttgtcccca gcctccatta tctttcttaa aaatataagt
   109621 atatttattt ctaaggtctg ttacaattag ataatcgcta gtacttttaa tattattttc
   109681 gttaacaaat ttaatcatgt cagtataaaa atacttataa tctaattcat ttggtttatt
   109741 cccatcaatt gataaaaaat aattaaaaac atatcctatt ttatcatcat atacaacctt
   109801 actccaatct ccatctactt gaaggacttc aaccctagat ttttcaggaa ttactgtaat
   109861 tatattggaa gttgtagatt tatcttctct taagtttaag ttactccaag catattcgct
   109921 tactgatacc aaatccttat acacatatcc ttcttgagaa ttgtacatca ccttaatcca
   109981 gtcatcttct tcatccaata cttccatttt agctccctga ggtattactg ttatgatact
   110041 tgaattggta gatttagcag acctcaaatt tacatttgct aaagcatatt tatatatagg
   110101 tgctctatat tttttaatat ttagtttagt taatttcaca catatccatc ctctcatatg
   110161 tctttttaca acattttatg aaattcgata tgtattcgtt ctcctatttt caaactttac
   110221 ttgtattact aataatattg ctacatatac ttatatattc tcacctatat ttatctattt
   110281 atttaaattt atgatattac attctttaat atactcttca attatacctc tagccacatt
   110341 aaaataactt atacacttgt caactatgac tgcatcacta ctaactactc tatctaattt
   110401 ttctaataca acatctgcat tttttactaa ttctacttca gtttcaattc cccaagtttt
   110461 ggcatgctct aatatcctat actttaaatt tcctgaatta gaaactggag catctaaata
   110521 aaatttaaga ttctgtgcat tgtatttatt aaaaaattta cctatcagat tcaaagcttc
   110581 ttctgtttta tctataatct tataggttcc cctaagacct gctaaatctc ttatattgcc
   110641 atcacttcct attactagag taccaccaga taatgctacc tctatggata ttatcaaatt
   110701 aaagccatct atatttacgg tatcttcttt gattttatct agagaaagcc tctttgattg
   110761 tcttataata tttttttcat cagtacagac tgcccttttt aatgcatctc tttgtcttat
   110821 agaaaactga tatctatcac caacaaaagt aacgactggg tctattttgt aatccctatt
   110881 taataaccat tctatttctt ctttagcctt tataagtctt gttaattctt tacttgaaaa
   110941 ccatctttta tcactatcat caaaccctct tttagatatc ttatttatat catttcacca
   111001 ccttgcttta aagatataac tgtactacat taaatacaga ttatttcacc ttttaagata
   111061 atttttaata ccattatctt atccatttag attattcaat atttataatt aattataacg
   111121 cttaacccca cttaataata cagaataata gattctatat tatatttata agtttataac
   111181 ataaataggt agtgttttaa aataaacttt ttagttcata agataatctt cttttataaa
   111241 atcaaatata tttttatcat ttaaacagta aaaaagagac ttatctctat tttttgagat
   111301 agcctctttc taaaatctac ttataatgat aattttaggt ttatatatta aacttatgtt
   111361 atacttcttt tatcatatta ggagatagaa tatcattaag agcttctgtc atagttggat
   111421 gtgcataaac acggtctctt aaatatgtat actctacttc taaatctaca gctaattgaa
   111481 taagatggat aatctcactt gaattttcac atatcatact agctccaagt atcttattgg
   111541 attttttatc tatcactatt tttataaacc catctgcctt gccaatctgt ttagctcttg
   111601 gaattgcttc tactggcatc tttgccacta atacttcata tcccttttct ttagcttgct
   111661 taacattaag accaactctt gaaaatgctg gacttataaa tatagaattt gggatattct
   111721 ttctatcatt agttgttcta gtcttatctc caaataactg attaataact atgcgataat
   111781 catccaatga aatataagta aattgtggac ctccatttat atctcctata gcccatatat
   111841 gctctttatt agtcttaaga gtttctgaga ctttaataaa tcctctttca tttaattcta
   111901 tacctgcatt ttctagccct agcccttcag tgtttgcttt tcttcctgta gctacaagta
   111961 tcatattact tgttaattct ttagatttac catctacttc atattctact attgctaatt
   112021 cagaaacttc tttaatctct tttatatttg cattattaac aatttttaca tttctctttg
   112081 caagtaattt tattatttct tctgaatcct caacatcttc atttggtaaa atgccattat
   112141 tagagtttaa tattgtaact tctgctccaa atgaactata aataccagca aattctaaac
   112201 ctataaatcc agctcctata attgtcattt ttttaggtaa agttcttaga ttcataagag
   112261 actcactatc atatactata ttcttatttt caattccctt aatattaggt ataaatggtc
   112321 ttgaaccagt attaataaat atattatctg ctactaactc ataaatttca ttttcagttt
   112381 tgacttgaac tgttttttca tcaatgaaag ttcccattcc tgtgaatata gttacattct
   112441 catttgaatt taatttatta tagttagctt ctctgagttt tgtaattaaa gtttcttttt
   112501 tatctatagc tttctcatat tcagcttgta cttcatccca agaatttata ttctttgttt
   112561 ttacgctgtt tgctgaattt tctaagcttt ttgttggtat acatgccaca tttacacatg
   112621 ttccaccata catcttgttt gacttttcta ttaaagctac ttttaatccc ctgtttgcca
   112681 aatcccctgc taatgttttt ccaccttttc caaatcctat tattatagca tcaaatgttt
   112741 ttttcatata aaattcaacc ctttcttgta ttgtttatac ttttactata acaagattat
   112801 ttaggtggta caattaggca cttttttgta accttaaatt gattcataaa cttatactta
   112861 aatactttta tttatttctc tgattttcaa taaatgatgc catagttgcc ttatccatag
   112921 ctcctggaat atactgagtt acatatcttt ccttgtcaat tataaatgta gttggaaaag
   112981 cattaattcc atattgatat gctaatgctc catcttcatc aagtacaaca gggaatgtat
   113041 aaccttgttc ttttaagaag ttaactacat gttcccttga accttctcta cctaaattag
   113101 gtgaagctac tcctaaaatt actacatcat cattattttt attatagtct ttatacagtt
   113161 gttctatata aggcatttct tctttacatg gaggacacca tgtagcccag aaatttaaga
   113221 atacaacttt gccttcataa tcacttaatt tatgtgtttt accatactgg tctgttaaag
   113281 taaaatcaat agactttatt ctatcttcat cattagaccc tttatcatta ttgtcattat
   113341 tagagtcttt ttgactatca ttaccatcag aattttcttc tttatcagta gaattttctc
   113401 gcttattttc ttcttgcttg ctttcaattt tactattttg tgacgtatta aagtgtttgc
   113461 ttatacttcc aaatccattt accatcatta atattcctga tactataagt ataatcccac
   113521 ctattttttt aataatttcc atgttagatt ttatcttatc tatagtttta aatagtttac
   113581 tgtaaaacat agctgtaatt atgaatggca aaataaaacc aatagtatat actgctatta
   113641 aaagattcgc actaagatga ttacttgaac ttgaaaccat gactaataca gatgccaata
   113701 ttggaccaat acaaggtgtc catccaaaac taaatgtaaa acctaatata aaagctgtta
   113761 ttgctttcat ttctttaaac ttaacattaa atcttttttc tctattcaat attgaagatt
   113821 taattattcc catgtaaaat aatcccatga taataattat aatcccacca ataaacatta
   113881 ttaaatcttt attttcatta aaaaacatac tcaatacttt tactgatgaa cccaatataa
   113941 agaatgttgt tgagattcca agagcaaaaa atatagtatt tttaaataaa gaacttccta
   114001 taaaactcgt ctttccttct tttaaatttt ctacactact atttgacaat atactcaaat
   114061 aaataggcaa aattggcagt atacatggtg aaaagaatga tactatacct tctataaata
   114121 ctaaaaataa atttacattt tgcaaattaa aattcctcct tattttattt ccaatattac
   114181 aatcccattt ctaaattaaa atctaactaa aaaattatgt aattttaata catttttcta
   114241 ctcatagctt aattaaattt tcattactta cagagtaaat tttagtattt atcacaattt
   114301 aaatttttat tgctccacat aatcattttt tccatgacag gaagcaatcg taatcctgat
   114361 tcacttaaaa aatatgttga ctctacaaca ttattaacca actttttttg gttgactata
   114421 atcccctgtt caattaaaaa atctagttgt tgaactaaca ttttcttact acagtctggt
   114481 atagctcttt gtagctctcc aaatcgtttt ttatcttctt gtattttcca tataattata
   114541 gccacccatt ttttacctaa aatatttgat aaagcttcta ctggacaatt atatatcata
   114601 tcatctatgt tgtacatttt attctcctct tttctttatt taatttatta aacaaacttt
   114661 tatagcaata tatttattaa tattataaat atacctagct ttatttaatt aaaattttta
   114721 tatatatact cctattacaa actattttag att
//
LOCUS       DAMKNB010000003       110995 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.003, whole genome shotgun sequence.
ACCESSION   DAMKNB010000003 DAMKNB010000000
VERSION     DAMKNB010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 110995)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 110995)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..110995
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.003"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            complement(775..1284)
                     /locus_tag="PC494_000197"
     CDS             complement(775..1284)
                     /locus_tag="PC494_000197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CarD family transcriptional regulator"
                     /protein_id="HDF3910730.1"
                     /translation="MVMFLFKIDDYIMYGMTGVCKVMDITNERFTNGIKKEYYVLSPI
                     YSNNTVIKIPVDNEKVPMRKLLSKINVLSLINDIPNMDTSWIDNEKLRSEQFKKILRG
                     GKCEELIKLVRSIDNNREYVKSIGKKTHQADDNIMKEAERLLNEEFATILDISPNEVS
                     SYISSHIPQ"
     gene            complement(1495..2916)
                     /locus_tag="PC494_000198"
     CDS             complement(1495..2916)
                     /locus_tag="PC494_000198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3910731.1"
                     /translation="MENYFDKQAKELYNKASEIINTHSMLKANRANEKFDIDIPQDFK
                     YEFFSLVDKVNLSLMEEEDNFYGYFLFQMSREIRFDISSPTGVNFKGAKYIIYFNPII
                     FLTLDIKQMETTIKHEIHHILSMHLMRAKELKGKYSTLAINMAMDIVVNKFLNNLPPY
                     ATTLEWVNLKYSLKLEPYEPFEYYVEKIQTELDLMEVDEDGEEDGEEDDSDKYGDIEI
                     DYSPERTHDIWDESNEIDENTLREFTEKFINSSQKGKVPAYLESMISSLKNSKGELPW
                     NLYLNRIMGTVENNKKKTITRRNRRQPNRLDLRGELRSHKSEIAVALDVSGSISDEEF
                     KQAIKEVLSIVKNYNHEITIIECDNEIRRVYKVRTEKDIKDRIRIGGGTRFSPVFEYA
                     NNKKINLLVYFTDGKGENKLQVIPRGYKILWVISGRGDKISLKEPYGAVKKLTKVKTN
                     DEILEINDVRNDGYSMNSQAPIL"
     gene            complement(2920..4050)
                     /locus_tag="PC494_000199"
     CDS             complement(2920..4050)
                     /locus_tag="PC494_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HDF3910732.1"
                     /translation="MNFIDTLKSVDLILSTGEVPLIVGESGIGKTALANKLAKENDWS
                     LIVIDGNLLKEGEIGGLPTIESYVGVNSNGYKTEKKTTVYAVHNKLREIDEEISKSKT
                     VLLFIDEINRCEHTVQQELMNLILNREINGYKLHDDVKILAAMNPSSKYGSDFDYQVV
                     DMDAAQENRFVWLNMESDHTQWIKWAIDEGIERKVIEFISTFPEYLHKINEDDVRATP
                     RSYERVSKIYKVYKEKNNSIPRAVFLNVVKGNVGKVIAEEFISFIESNSEPLISYEDV
                     FLGESIDESIVERVKNESHTRLYLSAMNILKDLELNIKNDKYESNHYINRFIEFLKMY
                     PVDLMIGIMKDIRNSYIEVYKKAIENEEFVKSYFESYSLIRG"
     gene            complement(4062..4865)
                     /locus_tag="PC494_000200"
     CDS             complement(4062..4865)
                     /locus_tag="PC494_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3910733.1"
                     /translation="MEKLRVIEMIKNNPNIIATIDNPTDEMKLLAIKENGLVLEYINN
                     PTREMQELAIDNNIRAIKFIDNPTEDMMIKAVNEGWSILDYIKNPTDKVIEMAINQAG
                     WAIKYAKNPSEELQLLAVRKNYDSIKFIKQPYESVQEEAVRISYDALRYIDSPSYNAE
                     LIAIKNNEAAISFITDLDKNKMLEFLKVNILVIKYILKKVSKDELESVLKEVLSKEDV
                     EEKYIRDFLNCSVIDRNSESIPIDKIMFIYKYGSKTAKKIAVDEKLKIM"
     gene            complement(5247..6128)
                     /locus_tag="PC494_000201"
     CDS             complement(5247..6128)
                     /locus_tag="PC494_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline iminopeptidase-family hydrolase"
                     /protein_id="HDF3910734.1"
                     /translation="MKITEGYMPFKGFKTYYRIVGENTEGKKPLVLLHGGPGSTHNYF
                     EVLDKIAESGRQVIMYDQIGCGNSFVEGHPELFNADTWIEELIELRKHLGLDEIHLLG
                     QSWGGMQAIWYAIEYKPKGIKSYILSSTLSSAKLWEKEQKRRISYMSEVDQKALLDAV
                     NTGDYSSKEYNDALERFMEMYCAGEVTEDSPECLRRPKKSGSEAYIVGWGQNEFSPTG
                     TLSGYEFTDRLHEIKEPCLVTSGAIDLCSPYIAKTMYDRIPNSKWELFEYSRHMPFVE
                     ENEKYIKVLTEWLNAND"
     gene            6584..7558
                     /locus_tag="PC494_000202"
     CDS             6584..7558
                     /locus_tag="PC494_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3910735.1"
                     /translation="MNNINSLKVIKLSLGCSLAIFIAWLLKLEYSMVAGVIVLLTVKD
                     TKRETLKGSIGKIYGFLLCTIFSYLCFNILGYNLTSFSIFIFIIIPLCFLLNIQDVIA
                     MCVVIASHYYLQGETSIKWILNEAGIFAVGTGIGVLINMYIPTNIHKIHEVQKKLQEE
                     VSIVLIDIADIIVNPKKENGYSRDLYTLNSLIDSSISETYDNINNTLLSDTRFFLEHM
                     DIIKSQRDILENLYSYVSQLNSTPPQAHILSAFIHKIGYTEFEAETGNLLLEELKRLM
                     ISMKNQPLPVDRTEFENRAILFLCLTELKQFLVNRKHAQMLRDNNFYK"
     gene            complement(7674..8735)
                     /locus_tag="PC494_000203"
     CDS             complement(7674..8735)
                     /locus_tag="PC494_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglutaminase domain-containing protein"
                     /protein_id="HDF3910736.1"
                     /translation="MKKIRKLATKLLITTIVLISGMSMTVYGMTAKEVTAKTPKSYVT
                     GTNSVYGPKLSQAQLNSVAQATADFMNKKITKNMTTDAKILVAYNHIKNNTTYVDWNA
                     VEGANTAYTLVTKKGACSGMARSMKALCDAMGIESYYVHSTSNDHQWNLIRFGDGRLY
                     HVDIDANKSAGKDIIYKSLSHPLPFDKTAYPKVGAIVQTVKPEQTQKPAPPGKHTMLP
                     HQEGAKAVANFGKKGEDINEKHVMYEGVRCSVVNSSVNTITFTGSESNLDPSNLTIAV
                     IGFMNTPYGMFALAPEGKPVEYPFKYDKPFSLDFSGKNRSGAELAKYCKKNDVTIKIE
                     ITDEKANIGLGQIMYVRYE"
     gene            complement(9346..10197)
                     /locus_tag="PC494_000204"
     CDS             complement(9346..10197)
                     /locus_tag="PC494_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HDF3910737.1"
                     /translation="MSCILKLKQIYEDLTEVDKKIADYILNNTEAISKLSVSELASNS
                     KTSTASIVRFSRKMGYSGFGDLKIEIAKDLMGKENEYTYVDENYDCNIDSVINKITNK
                     NIETINQTRLLNEKDIIKEAVEQIIKAKNVYIFGVGGSALVALDLQMKLLRINKQAFT
                     SLDSHTQLMVSSNVDKEDIAIAISYSGESKEVIKSIENAKLKGCKVICITKYSDNHLS
                     KISDLKLVVPNIEKRLREGAISSRIAMLTLIDIIYISIIQENLNEAEQKLQETKRILD
                     YLNINNA"
     gene            complement(10214..11134)
                     /locus_tag="PC494_000205"
     CDS             complement(10214..11134)
                     /locus_tag="PC494_000205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA reductase"
                     /protein_id="HDF3910738.1"
                     /translation="MYFLGVDGGGTKTTFTLVDEELNIVGTITKGTCHYNQIGFDNLT
                     KLLITGLEEVCKDAKINVEEITYAFVGLAGYGKIKEVLYALEVATKNAYSHINYTLGN
                     DVEIALAGSLNGEKGINIIAGTGSIAQALDKDGNLHRCGGWGYVLGDEGSAYYIGMAT
                     LKMFTMQSDGRCSKTKLYDLIKRHLNIENDYDIIKYVNDEIQGDRIEIAKFATICLKA
                     VIEGDNTASKIFDDAAYELSRLIIGLEHHFEQGTKIKVSYSGGVFKSGDLILEPLKKY
                     LNKTRFGIVRPVLTPDLGACLLAKKKYYSK"
     gene            complement(11244..12158)
                     /gene="murQ"
                     /locus_tag="PC494_000206"
     CDS             complement(11244..12158)
                     /gene="murQ"
                     /locus_tag="PC494_000206"
                     /EC_number="4.2.1.126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramic acid 6-phosphate etherase"
                     /protein_id="HDF3910739.1"
                     /translation="MLIKTLENLVTEGRNKNTLQIDKEDTLGIIELINNEDKTVAYAV
                     EEQKESIAKAVNIIVDRMKQGGRLFYIGAGTSGRIGILDATECPPTYGVDFELVQAII
                     AGGNQAIFKAIEGAEDDKELGKQDIIDRGVTSKDVICGIAASGRTPYVIGAMEYAKEL
                     GCAVLSITMNPNSEMSKKADLPINIIVGAEVIMGSTRMKSGTAQKMVCNMLTTASMVK
                     MGKVYSNLMVDVKTSNEKLVERAKRIIMIATNVKYDVAEKFLEEADNSVKLAIFMIKS
                     GLDKDSAKSILDRQEGYISEALKSIEKL"
     gene            complement(12257..13354)
                     /locus_tag="PC494_000207"
     CDS             complement(12257..13354)
                     /locus_tag="PC494_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HDF3910740.1"
                     /translation="MGRLGISIYPEKTTSKEIYDYIDKAAENGFTRIFSCLLSVKDTK
                     ENIIKKFKSINEYAKFKGFEVILDVNPRVFGELEISYKDLNFFKKTKADGIRLDMGFT
                     GSEEALMTFNPQNLKIEINMSNNTNYIDTIMDYQPNKENLIGCHNFYPHRYSGLNLEH
                     FIKCTERFNKYGLRTAVFVTSQNETTFGPWPVTDGLPTIEMHRNLPIDIQVKHIIAMN
                     NINDIIISNCYPTYEELKVLGSMRKDMVTFDVAIEENIREVEKKILFEEIHFNRGDIS
                     DSLIRSTQSRVKYKGYKFELFNTPKIIKRGDIVIESSEYGHYAGELQIALTDMKNSGK
                     SNVVGYIRKEELFILDYIKPWQKFNFKPSTK"
     gene            complement(13587..14933)
                     /locus_tag="PC494_000208"
     CDS             complement(13587..14933)
                     /locus_tag="PC494_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDF3910741.1"
                     /translation="MLDKFTEFLDTKLSTSMARLAEQRHLRAVRDGIVASLPLIIVGS
                     FFLILAFPPLPDSWGVTQYLKENAVTILLPYRMTFFIISVYSTFGIGYSLAKSYKLDG
                     LTGGLLATATFLLTIVPTAIEGLTPDLLKIVEKSPELLAWYNSIPQGWQMPMANLGGG
                     SMFVAIVTSIIGVEIYRFTDKSKFKITMPEAVPASVTRSFEALTPAALIIILMAIVTY
                     FLGFDWHGFIAKLVTPLVSATDTLPSVIILIFLITFFWSFGIHGVSIIGSLARPLWIQ
                     LLDANTASYAAGQAVPGIAAEPFFQWFIWIGGSGATIGLALLLAFRAKSAYGKSLGKA
                     TVIPAIFNINEPIIFGAPIVLNPILIIPFVVAPIVMATVSWFAMSANLVSRVVVTAPW
                     TLPGPVGAYLATGGDWRASVLNLLCIAISIIIYYPFVKMYDKRLLHEEKVEEQEAY"
     gene            complement(15022..15330)
                     /locus_tag="PC494_000209"
     CDS             complement(15022..15330)
                     /locus_tag="PC494_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDF3910742.1"
                     /translation="MRVLFVCSSGMSSAIAVNALQKEGAKNGIDIDVLAVGTQEFENE
                     VKNGWDIAMVAPQVRHRFDYLKAFADEVSVPCALIQAQAYSPLGGPKLLKQVQELLSK
                     "
     gene            complement(15592..15990)
                     /locus_tag="PC494_000210"
     CDS             complement(15592..15990)
                     /locus_tag="PC494_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3910743.1"
                     /translation="MSNNKKKKRKKNNNYKNAKSTKSNKNTKKQMEKNQRTDYNIPTI
                     SFKSGLILIVSSLVSTVVFPLLLSIFGIDNRFGVVIGNSLITSFAVAYTRYFVETKRG
                     FSLGFFRLYILFALSFAIIGYFWIYKGIHI"
     gene            complement(15992..17152)
                     /locus_tag="PC494_000211"
     CDS             complement(15992..17152)
                     /locus_tag="PC494_000211"
                     /EC_number="2.7.1.170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anhydro-N-acetylmuramic acid kinase"
                     /protein_id="HDF3910744.1"
                     /translation="MITMYSVGLMSGTSLDGVDAVLAEISGNGRNTKVKQIEFITLEI
                     PKDIKDEIRKCCIEEESSVDLICSLNFKLGYLFSKAVKSVCHKANFHIANLDFIASHG
                     QTIFHIPRSYNNFVSSTLQIGEPAVIAYETNTKVISNFRVMDIAAGGEGAPLVPYSEF
                     LLYSDNNKNLALQNIGGIGNITIIPKSCNIDDVFAFDTGPGNMIIDGVCQRLFNRKYD
                     KNGYFASKGKINEEMLKDLMSHKYLSQAPPKSTGREVFGQVYLDNMLNKYKHVDKYDL
                     IATVTMFTAKAIYYNYKNFILPKVNVDTLLIGGGGAHNLTLIGYIKELLLEVEVLTQD
                     EYGYSSDAKEALAFVILGNETLNNSFSNVISATGAKNKVILGNITPKPFGGK"
     gene            complement(17583..18602)
                     /locus_tag="PC494_000212"
     CDS             complement(17583..18602)
                     /locus_tag="PC494_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF3910745.1"
                     /translation="MLVKYLKGRSKYIALPLVVVSIINIYLFAIDIFKNKYSELIYLD
                     FLVLFIIMVFFVIDYINFRNSYTNLYNCIENSGEIDSYLVDGQSFEENLIKDIIENLK
                     IKNNSDIETYKQSLKELDEYIAKWVHEIKIPISSLSIITDRLSSIEDSLDIKNQVAKI
                     NFLVNSILYSSRSNTMFEDVFINKFNLEKLVKMSIKNNSFLLIKNNVEVSLNELENDV
                     YTDSKCMSYVLDQIINNAIKYSKEVGKIEFNSKKLENGVVLSIKDFGIGINEEDISRV
                     FDKGFTGKNGRNQLYKSTGMGMYFVKKMIDSLGHEIEVCSENGSYTIFNIYFYDISDY
                     LSLDS"
     gene            complement(18596..19276)
                     /locus_tag="PC494_000213"
     CDS             complement(18596..19276)
                     /locus_tag="PC494_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF3910746.1"
                     /translation="MYRILLVEDDIDLSKEIALALEKWGFKVELIDDFEVVLDEFIDK
                     KPDVVLLDVNLPLYNGFYWCEKIRAISNVPLIFLSSRDSDMDLIMGINNGADDYITKP
                     FSIEILVTKINGIIRRVYNYSDSNSILYCEDLMFDVGKGIIKHKYKDKSIELTKNEIK
                     ILTLLLKNKNRVVSRESLMMTLWDNDEFVTDNALTVNMNRLRSKVKELGFDDFIKTKK
                     GIGYIIQC"
     gene            complement(19428..21331)
                     /locus_tag="PC494_000214"
                     /pseudo
     CDS             complement(19428..21331)
                     /locus_tag="PC494_000214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891367.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
     gene            complement(21332..22084)
                     /locus_tag="PC494_000215"
     CDS             complement(21332..22084)
                     /locus_tag="PC494_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF3910747.1"
                     /translation="MKEILKIKNISKDYGIKGFKTNVLKNISLTVNEGDFISIMGPSG
                     AGKTTLLNLMSTLDKQTSGEIILDGINISKVKNNELSKLRREKIGFIFQDYNLLDNMK
                     LMDNIALPLALGKKKSKEIEAKVFSIAKKFGLENHLDKYPYQLSGGQKQRGAAARSLI
                     TNPTVIFADEPTGALDSKSAYELLESLEKINRENNATIIMITHDPLTASYSNEVYMIN
                     DGNIKCKLNKGNSRKEFYGKIMDMLASMGGEM"
     gene            complement(22400..23554)
                     /locus_tag="PC494_000216"
     CDS             complement(22400..23554)
                     /locus_tag="PC494_000216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDF3910748.1"
                     /translation="MINKAIKFKFIIFYFFSYIIFAFASTKFTPFLSKLGYSAFERGI
                     ILSSYAITNILFQLLFGVLADKYQTMKKIVLISLSVYGIASVIMFSTESATFIIYLLL
                     VALSGGLLNTCCSLYDTWIIGCGDNINNYLSFIKTFGSIGWAIGSMVASYLILRFSYF
                     GLSVAIGLIVVLLIINILLLPDIEKINKKINVTNKDIIELLKDKKYILLVCILFLLYS
                     MVVANNCTVIDKMIALNATNSQISLKWSLQSLLEIPTYLAGSYLLKKYSSLNLLKLSA
                     IMITVQFLLFALTNDSNIIIILCVFQVFSTPLILITSKRLIFEVSPKKLRSSSQLIAL
                     SIFMGGSFLIIPTVAGFLSINIGYNYTLMVLSLFGCLAYCLIVLLNYLQE"
     gene            complement(23557..24024)
                     /locus_tag="PC494_000217"
     CDS             complement(23557..24024)
                     /locus_tag="PC494_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HDF3910749.1"
                     /translation="MFFKRKKEAITINSYIDGKIINLGEIPDKVFSTKVMGDGFAMIA
                     KDNILKSPTKGVISFIAQTNHAIGIKLQNDVQILIHIGLDSATTKKENFKLEVKQGQE
                     VNMGEKLVEIDNKLLENTLYIPLVIVENPNTVKYHLSNLNQEGNSGIKVINFD"
     gene            complement(24038..24526)
                     /locus_tag="PC494_000218"
     CDS             complement(24038..24526)
                     /locus_tag="PC494_000218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3910750.1"
                     /translation="MITNKIKNITAVLKDENIFLSVVMVCFLILPVLYIVYLELTSLF
                     TNISFSQLLNNDVNASLNLISNFSAVYSAYVIYNIKKNKEIKENMIAFYLVLLGQIFQ
                     IYTITIVIMFTYIYKFVGIKQIISSIKELQWGKSYKALFSSIAVCLISLFVMIIRIKL
                     IM"
     gene            complement(24540..25871)
                     /locus_tag="PC494_000219"
     CDS             complement(24540..25871)
                     /locus_tag="PC494_000219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-alpha-glucosidase"
                     /protein_id="HDF3910751.1"
                     /translation="MERKRQRILIAGGGSTYTAGIVTMLIESVAKFPIESIKLYDNND
                     ERQRKVAEACAIIVREKNPEIKFSYTTNPEEAFTDIDFVMAQIRVGLYALREQDEKIP
                     LKYGVVGQETCGAGGIAYGLRTIGPIIEMIDYMEKYSPNAWMLNYSNPAAIVAEACRV
                     LRPNSRIINICDMPVCLEEIFARVLGLNSRKDFDVRYYGLNHFGWWTSIKDKEGNDLM
                     PKLQEYCAKKGYEEFTPQGQHKESSWLETMRAAKDLLEIEPTTLPNTYLKYYLMADET
                     VEHANPNYTRANEIMDRREKDTFEECERIIKNGTARDTWFDASEHSQFIVELACALAF
                     NTQERFLLIVPNNGAIENFADDAMVEIPCLVGKDMVEPMSIGKIPTFQKGLMEQQVAS
                     EKLAVEAWIEKSYQKLWQSFTMSKTVPSAKVAKEILDEMIVANKDFWPTFK"
     gene            complement(25885..27450)
                     /locus_tag="PC494_000220"
     CDS             complement(25885..27450)
                     /locus_tag="PC494_000220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003233606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HDF3910752.1"
                     /translation="MMKKIQRFGGAMFTPTLLFAFAGIMVGFSIVFQNQSIMGSPATP
                     ENIWYQFWGVISSGAWMVFNQLPLLFAISLPIALAKKQQARACMEALATYLTFNYFVG
                     SMLSFWGKSFGVDFAAEISAGSGLVSIAGIKTLDTGMVGALLISGIVIYIHNRFYDKE
                     LPDFIGLFRGSSLVVAICFFVMIPVALLTCFIWPHIQNVIRHLQTFFINSGNIGVWCY
                     AFLQKILIPTGLHHFVYAPICYDSVVVPGGTSVYWATHIQDFQTSAKTLKEMYPIGFS
                     LSGLSKVFGSLGVFGAFYVTAKPEKKKKVLGLMIPATLTAVLTGITEPLEFTFLFVAP
                     LLFLVHAFLDACLQTISFALGVVGDFGGGIINWVVLNWLPLGMYHWKVYVVQVVVGII
                     FSFIWFFVFTFLIKKFDMKTPGREEDSEETKLYTKNEYLETKDEKGNKLSKASQQAYE
                     YIKLVGGAENVVDVTNCATRLRLTLKDDSIISKEEDFKAVGAHGLVHNGKAIQIIIGL
                     SVPSVREEFENLL"
     gene            complement(27620..28405)
                     /locus_tag="PC494_000221"
     CDS             complement(27620..28405)
                     /locus_tag="PC494_000221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HDF3910753.1"
                     /translation="MRLEEMIFLNYNKLNDTDLLIWKYITANKKHCSKMSINELAMKC
                     NVSRATITRFVKKLDLKGFSEFKVLLSWESEKVHVIENQSFDIACNSIIKYVEDQKNK
                     DYDALCKLLYESRTIYAYGSGDIQNVVAKQIKRMFLSCQEIIYDFEGRTFDDSFYNIV
                     SKNDVMIIISLSGENENTLNIARRLKLIGTKIISITEFKNNTLTDLSDESIYISATNI
                     SFLQMHPSYKLTMLYFILIELLFIKYSIYKRHRMITEGIDCKL"
     gene            complement(28572..29771)
                     /locus_tag="PC494_000222"
     CDS             complement(28572..29771)
                     /locus_tag="PC494_000222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase S41"
                     /protein_id="HDF3910754.1"
                     /translation="MKKKVLFLVIILAFIILLGNSTYSQKNQLSEEEKVDDFNYVYNV
                     VKTGYPYLGVNKRLNNIDWLANKDEYTKRIKNTENDEEFIEELSSILSDLNNKHTEVI
                     DNKKRYELFKKSYSNNDWYDFLNDKKVVDRYDSMNLKIKMPDDIFVKKELILKDVIKG
                     QIGYMYLPSMSSKNGSINNDLKIIGDYINTLEKHKALIIDIRGNLGGSDRYWQGIVSK
                     LIKNDVKINGYRIYRNNNEIVKKYTNARNIKLNPVENLPASVKENAPKEIIKDFNDFE
                     DTSYTIKSTDDSKFKGNIYLLVDRKIYSSSESFAMFCKENKFATLVGETTGGDGGCID
                     PVLFNLKNSGLIVRMASCMYLNKNGICDEEFKTIPEFKVKDCKRTADFKDDNCIRKAL
                     ELENINY"
     gene            complement(30293..31630)
                     /gene="xylA"
                     /locus_tag="PC494_000223"
     CDS             complement(30293..31630)
                     /gene="xylA"
                     /locus_tag="PC494_000223"
                     /EC_number="5.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xylose isomerase"
                     /protein_id="HDF3910755.1"
                     /translation="MSEIFKGIGQIKFEGVKSDNELAFRYYNPEQVVGNKTMKEHLRF
                     AMSYWHTLCGEGNDPFGVGTVERPWNNITDPIEIAKIKVDAGFEFMSKMGIEYFCFHD
                     RDIAPEGRDLEETNKILDEIVEYIKVNMEKTGIKLLWGTANMFGNPRFVHGASTTCNA
                     DVYAYAAAQVKKAMEITKYLGGENFVFWGGREGYETLLNTNTELEMDNFARFLQMAVD
                     YAKEIGFSGQFLIEPKPKEPTKHQYDFDTATVLGFLRKYNLDKYFKMNIEANHATLAG
                     HTFQHELNIARINNVLGSIDANQGDLLLGWDTDQFPTNIYDATLAMYEVLKQGGIAPG
                     GFNFDSKVRRASFEVEDLFLAYIAGMDTFAKGLLIAHKLLEDEVFENFTKERYASFSE
                     GIGKDIVEGKVGFKELESYALQMPVIKNKSGRQEMLEAILNRYIYEVDTISNK"
     gene            complement(31726..33276)
                     /gene="xylB"
                     /locus_tag="PC494_000224"
     CDS             complement(31726..33276)
                     /gene="xylB"
                     /locus_tag="PC494_000224"
                     /EC_number="2.7.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xylulokinase"
                     /protein_id="HDF3910756.1"
                     /translation="MKLEYVLGVDIGTSGTKTVLFDKLGNTIKSCTYEYPLIQEKSGW
                     AEQDANDWWKAVVESIREVVQSSNISSECIKGIGLSGQMHGLVILDNEGKTLRNSIIW
                     CDQRTVKECEEITDLVGEERLIEITANPALTGFTASKILWVRNNEPDIYKNTNKILLP
                     KDYIRYKLTGEYATEVSDASGMQLLDIRKRDWSDEVLEKLNIDKNLLGKVYESQEITG
                     YVTRDVASLTGLKEGTIVVGGAGDQAAGAIGNGIVKDGVVSSTIGTSGVVFAYTKEPK
                     IDKEGRVHTFCHAIPNTWHVMGVTQGAGLSLKWFKDNFCQSEVEVSNSLGEDVYEIIN
                     NQVSKVPTGCNGLLYLPYMMGERTPHLDPYARGVFFGLSPIHSKKEIARSIMEGVSYS
                     LKDCMDIIENLNIDVNEVRASGGGGKSKVWRQMQADMFNQDVYTINSSEGPALGVAIL
                     ALVGAGIYENIQKACDAIIKTSTKLEPISENVDTYNIYHRLYKRIYKSLKDDFKLLDE
                     VVNAKINN"
     gene            33484..34644
                     /locus_tag="PC494_000225"
     CDS             33484..34644
                     /locus_tag="PC494_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HDF3910757.1"
                     /translation="MVTDKYTIREMNERLVLEQIIKNGPISRASIASTIGLNKATISA
                     ITKKLIDESLVHEIGIGNSTHSGGRKPILLVFNKCAGISLSMDIGYDYIFSSLSYLDG
                     TIINSKKLTDIQVSKDNVIQLIDEIINSYNISKIDTPYKVIGLTLAIHGITCENKVLF
                     TPYYNLNEIDLYSILSKKYDFPIHIENEANLTALAENTFSTVHNSLLSLSIHSGFGSG
                     IIINNKLYSGRNGMSGEIGHTIIMPNGKLCPCGNRGCLEQYCSEKKVFEQLSSLENIP
                     KIDSDIVKQLYYEDNQNAKKVIHEFCSYLTIAINNAITTYAPEIIYLNSQIISDIPEI
                     LQITKDMLVSSFNKGINIEISSLGSEASLYGGSAVNIKSFLNIQNLTLINEI"
     gene            complement(34800..35204)
                     /locus_tag="PC494_000226"
     CDS             complement(34800..35204)
                     /locus_tag="PC494_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDF3910758.1"
                     /translation="MNSIILMSHGNMAEEVLNSAKMIIGDSIDYPTVNMKQDDGIEGT
                     IEKLKKALEVYKESSEIIIMADLLGGTPCNAALLVANNDSRIKIISGLNLGMVIESAF
                     LDTKELAAKLEKIGKDNISMVEQNASLLSDDE"
     gene            complement(35225..35707)
                     /locus_tag="PC494_000227"
     CDS             complement(35225..35707)
                     /locus_tag="PC494_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDF3910759.1"
                     /translation="MEMKGIKNIRIDDRLIHGQVATMWSNKLGVTRLMVVNDAVANNS
                     VQKQVLRMATPAGIASSIITEETAIKNITAGKYEGQNVLLIVKSPVDLIPFVEAGFKI
                     HNINVGNMSSRKDTTVLRPNISVTEEEKEAFKRLLDEGIEITTIMTPDDKKTYLVDIL
                     "
     gene            complement(35727..36536)
                     /locus_tag="PC494_000228"
     CDS             complement(35727..36536)
                     /locus_tag="PC494_000228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HDF3910760.1"
                     /translation="MSDKVSLNKSNEKVKKSVLWRWFFTSSVSSNYEKMQALAYCYAV
                     LPFLKVVYKDNPEKLQSAVLNHLQFFNTNPWVAPYILGINVAMEELSSEETEEAVASI
                     KTGLMGPVAGLGDSLFVVIPWTIFGAIAANMAIDGSPFGILLWIVVSVALKLLSIPLF
                     NAGYTSGTKLISSIEKSLKILTESTSILGLMVVGALIPSVVKANVALNFQQGDFTMKG
                     QEILDQIMPGLVPAILVVIVYWALKKNIKPIYLILGVMVVSIILYALGILK"
     gene            complement(36529..37308)
                     /locus_tag="PC494_000229"
     CDS             complement(36529..37308)
                     /locus_tag="PC494_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDF3910761.1"
                     /translation="MEPQLWQLLLIVLYGFFINYEKNSTMFGTYQPVTAGFITGLILG
                     DINTGLYIGGTLQLLSLGISNFGGASIPDYQTASIVATFITITTKQEASVGISIGIPV
                     ALLMVQLDVLRNTIGIWLVHKAEDGAKKGNYKNITYMQMLGVLLTAATTGIPVALSVI
                     FGPSLINTILKYTPEWLTGGLTVAGGLLPAVGIGLLLRYLPAKEYFSYLVIGFVLAVY
                     MKVPLLGVALIGGAIALIIYKKNLENQEQQYTVVGGMDEDE"
     gene            complement(37308..39386)
                     /locus_tag="PC494_000230"
     CDS             complement(37308..39386)
                     /locus_tag="PC494_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase"
                     /protein_id="HDF3910762.1"
                     /translation="MIKISEDYIEKRFDNELLRIEAWGKNSLRIRSFVDQNFVDENYA
                     LNEKPKLNKDDITINKNEDGSAIIKNGKIKAVLDHRDRITFYNDKNEILLKEYIRLRA
                     VKHDDGGEDVGTIEITKDFNSTLKLKSREYRPSYSGEFEVTTRFESEPSEKIFGMGQY
                     QHKFLDLKNTVLELAQRNSQISVPFYISSLGYGLLWNNPGIGKVSFAKNMTEWKMFST
                     NFIDYWITCGESPKELNKNYSQVTGTVPMMPENLLGLWQSKLRYRTSEEVLDVVKEYS
                     KRGIKLSSIAIDYFHWPKQGEYKFDLDYWKNPKELVKKLKEEYSVEPIVSVWPTVQSD
                     AENYNDYLENGYLVNVNRGVRMTMQIQGNTVFVDMTNENAREYVWDRIDKNYKQLGID
                     YYWLDVAEPGYSVYDFDNYRYKKGNVLSCGNIYPIDYLKMIYDGLHNDIESVVTLVRG
                     AWAGAQKYGALVWSGDIDSSFEAFNNQVNTGLNMGLAGIPWWTTDIGGFHGGNPKDPE
                     FRELMVRWFQYATFSPILRMHGDRLPHSKPLSNKGGGSMVTGAPNEIWSYGEEVEVIL
                     TKFIKIRESLKTYLKKLMKEAHEDGTPVMRTLFYEFPEDDKTWEVDNTYMLGDEILVA
                     PIMNYKDRSRKVYLPKGHTWENIFSGVSYEGGKTYEVECPLEEIPIFLKQDSSYNFKE
                     LKNILGEVKS"
     gene            complement(40185..40706)
                     /locus_tag="PC494_000231"
     CDS             complement(40185..40706)
                     /locus_tag="PC494_000231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF523 domain-containing protein"
                     /protein_id="HDF3910763.1"
                     /translation="MKRNREIVVVCHCILNCNSKVEGLSEFKGAQNIAIDLINKGYGI
                     IQLPCPEMIMYGINRWGHVKEQFDNLFFREQCRQMLIPHVRQFDEYLKNDYDIKSIIA
                     IDGSPSCGYNKTCSSKRWFGELSGCNELMDKINDIQMVDGKGIFIEELEKLLKEYNLE
                     IPIVGFDELREDK"
     gene            40872..41438
                     /locus_tag="PC494_000232"
     CDS             40872..41438
                     /locus_tag="PC494_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HDF3910764.1"
                     /translation="MDTKKVTFSSMCIVINIVLGMVISMINIPLLFLDTVGTVLGAVV
                     LGPFWGALIGGCTNLVLGVISGPTNIPFALVNIVLGLIVGYISKKKGFGYKEAIITGV
                     ILSIVCPLIGTPISVLLFGGLSGSGADLLVGFLVQSGQKIFTAAFFPRILSNIVDKPL
                     SCIMVVYFISKMPKGFIKQYSKNTSSSY"
     gene            complement(41655..43718)
                     /locus_tag="PC494_000233"
     CDS             complement(41655..43718)
                     /locus_tag="PC494_000233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF262 domain-containing protein"
                     /protein_id="HDF3910765.1"
                     /translation="MKAGEIEFLSYLEGSNKSFVVPVYQRNYNWKKEQCKRLFDDLED
                     IIDSGFRTHFLGSVVSIYSMGKEYLIIDGQQRVTTVSILLIAMCQIIKEFGESKGIIT
                     TEEQIKECYLINKHSRDKDGKIKLKPIAEDRKAYYELFEEEMNTDRNSNIVSNYLYFY
                     NRIKEDNISIDDLFDAIQKLTIVEIELKNGEDDPQLIFESLNSTGLDLSEADRVRNFV
                     LMGRSSKLQEEFYNNYWYKIEKNTSSNVSSFIRDYLTIKERSIPNKNKVYFSFKRYVS
                     DNGIDIEILLKDLLKFSNYYREISYSCTDDNDVNKVLKRINKLEIFVSYPFILELFDD
                     YNEGIINKKVLVESLNLVECFILRRIVCDVPPNALNKVFMNLGREIKKFSDYKENYSN
                     ILRYIFINKKSSQRFPTDSEFSNAFETKDIYNTKSKNKLYILERLENYNNKEIVDLEN
                     LINNNMLNIEHIMPQTLTNKWKESLGDNYKEIHDKYLHTIGNLTLTGYNSKLSNKTFE
                     EKKEMEDGFKDSRLYLNKYISSIDKWNEEEIKNRTKILLDRAVEIWKYPSVTYEPPSN
                     SENIFTLEDDDVNFTNESIVSFSILGESYKAKNWTEFYEQVALTLYDLDSVRFNSIVD
                     KTYKRDFIDNIKSRDAYKLRKGIKISENIYLETNLNTEAKLNIIRFLLNEFDIELNEV
                     IFSIK"
     gene            complement(44099..47434)
                     /locus_tag="PC494_000234"
     CDS             complement(44099..47434)
                     /locus_tag="PC494_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HDF3910766.1"
                     /translation="MGNFDFLQKKKNFNSFNTACLEAEKSILVSPSTCATITRRALEL
                     AVKWLYANDSDLVLPYQDNLSTLIHNNSFIELIDYDMLPLLKYIVKLGNLSVHTSANI
                     ERGEAILSLNNLHQFVSWIDYCYSDEYTAEDFNEDLLLHGEEKRTRPDELKNLYERLS
                     SKDKKLEEVIKENEELRKSLTEKRKVNTANYDFKIDEVSEFETRKRYINIELKLAGWE
                     FGKDIWEEIEVQGMPNESGVGYVDYVLYGENGKPLAVVEAKRTSKDPKIGQQQAKLYA
                     DCLEKRYSQRPVIFLTNGFDMYIWDDYSDRKVYGFYKKSELQLMIDRRKSKKSLTSVT
                     INDEISNRYYQKEAIRAVCEALENKQRKTLLVCATGTGKTRIAISIVDVLSRHNWIKN
                     ILFLADRKALVKQAKKSFTKLLPNLALCNLLDSKDSPEDARMIFSTYPTMMNAIDDTK
                     SKDGKRLFTPGHFDLIIIDESHRSIYKKYKSIFDYFDSYLMGLTATPKDEIDKNTYSV
                     FDMENGVPTYAYEYNKAVEDGYLVDYTSIEFKTKIMEDGIKYDELSDEEKEEYENTFN
                     DDESIGDEIGNNAVNEWLFNSDTIDLVLNKLMTEGLKIEGQEKIGKTIIFAKNTKHAR
                     AIVERFNKLYPKYGGNFVKAVDYSINYVDSIIDDFSDKNKLPQIAVSVDMLDTGIDIP
                     EILNLVFFKKVRSKTKFWQMIGRGTRLCPDLLGVDMDKERFLIFDFCNNFEFFKFNPK
                     GFEGNKAETLTEKLFNIKVSMVKELQDIKYIEGEYAELRKELLEELITSVKALNEDSY
                     IVRMNLSYVHKYKNENVWSNIGAVAQNEIREYISPLITSYSDDELAKRFDVVMYNIQL
                     AYLQNNNASKGIRHVMATAEKLSKLGTIPQIQQQKYTIEKAMTEDFWEDSDIFEVEEV
                     RISLRELIKYLEKSSQKIYYTSFEDMIVAEDRNDSVYNANNLKNYKKKVEYYLNSHKD
                     ELAIFKLRNNKKITKQDVETLEEILLKQLGNCDDYKKEFGDTPVSQLVRRLVGLDREA
                     ANEAFSEFLNNKSFNTKQIHFVKLIVDYVVKNGFIEDNKVLMEDPFRTVGSIIDLFEN
                     HIEERNKLIKTINKIKENASEIG"
     gene            complement(47483..47911)
                     /locus_tag="PC494_000235"
     CDS             complement(47483..47911)
                     /locus_tag="PC494_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3910767.1"
                     /translation="MVIRNKLSWNSIEEVNRDFGSCLYDLQNFKILYDKEEMPELWAR
                     YIKEGFKSYMVSFLELTKAMLYYKSIDLNIKSKNFYDYLLACEYHNLLPKNSSIVIET
                     LRKLRNDDSHGYDIPQFEDMYELFTENEEVFVSIRNSCKK"
     gene            complement(47901..48281)
                     /locus_tag="PC494_000236"
     CDS             complement(47901..48281)
                     /locus_tag="PC494_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase domain-containing
                     protein"
                     /protein_id="HDF3910768.1"
                     /translation="MRNIPNEIKNSIINVFPKENTLAIIIFGSYGTDKHTSESDIDIA
                     WIPIKKVPITELATKTEALRNILDIDVDLKIVTDNYTIALKKAILEGEVIYESKDFKD
                     YINKFYFENSDVIDILDWRDMYGN"
     gene            complement(48314..48622)
                     /locus_tag="PC494_000237"
     CDS             complement(48314..48622)
                     /locus_tag="PC494_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3910769.1"
                     /translation="MNQIELDLYHNMVNIYKEADLQCNYKPTRFLQLINNKGALLAAK
                     ELINKEGATEGFTRLWECKRLDLSLEVLVLKEKYKELFTDEEREICINRLKDYGYKFN
                     "
     gene            complement(48655..49839)
                     /locus_tag="PC494_000238"
     CDS             complement(48655..49839)
                     /locus_tag="PC494_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HDF3910770.1"
                     /translation="MVDEAKILDVVSISGENVKKFDGERSYLSTGNLDFNKISNLEIV
                     TYENKPSRANQTVNIGEVIFAKMKDTKKTLVINKTNKNIIVSTGFYVLKPSKEILPQY
                     LYHYLNSSYFLNQKNRLSKGATQSALNNEGLANIKIRMYNLKVQEKVVRVLDKAQELI
                     DKRKEQIEVLDELVKSRFIEMFGTPSKNEKNWEISEIGKYLDVLTDYHSNGSYETLRD
                     NVTLLDTKGYALMVRTTDLENNNFEKGVKYIDEHAYNYLEKSKVFGGEVIINKIGSAG
                     KVYLMPFLNKPVSLAMNQFMLRFNEDKVNHIFLYNLLLTSYMESKIKEKVRGAVTKTI
                     TKDAVRKINIIVPPIRLQNQFANFVKQVNSLKFEMETSLKELEDNFNSLMQKAFKGEL
                     FN"
     gene            complement(49843..51306)
                     /locus_tag="PC494_000239"
     CDS             complement(49843..51306)
                     /locus_tag="PC494_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HDF3910771.1"
                     /translation="MITGELRSKVDKIWETFWTGGLTNPLEVIEQFTYLLFIKGLDEV
                     ETKNEAEATLLGVSFERIFNDEHQHLRWSKFSNEGNSEKMYEIVQNEVFPFIKKLHGN
                     KDSAYAKYMGDAIFKIPTPLMLSKIVDGISNLELSKDRDTKGDLYEYLLSKVATAGTN
                     GQFRTPRHIIDMIVRLIKPTPEDIIVDPAAGSAGFLVSSQQYLRDNHSSLFLVQGLKE
                     HFNNGMFYGFDMDRTMLRIGAMNMMLHGVDNPNIEYKDSLSEVNTDKDKFTLVLANPP
                     FKGSLDYEAVSADLLKVTKTKKTELLFLALFLRVLKIGGRCACIVPDGVLFGSTGGHK
                     SIRKEIVDNHKLEAIISMPSGVFKPYAGVSTAIMIFTKTGTGGTDKVWFYDMKADGYS
                     LDDKRNEIKDSDIEDIIKRFDNLDGEVDRKRTEQSFFVDVEEIRENGYDLSINKYKEV
                     VYEEVVYDAPSVIMGRVKALEKEIVDGLEELERMLEV"
     gene            complement(51816..52685)
                     /gene="gatY"
                     /locus_tag="PC494_000240"
     CDS             complement(51816..52685)
                     /gene="gatY"
                     /locus_tag="PC494_000240"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase subunit GatY"
                     /protein_id="HDF3910772.1"
                     /translation="MALVTTKQILLDAQEGHYAVGAFNVENMEMVMAVIEAAEELKSP
                     VILQTTPSTIKYAGLDYYLANVKVASEKASVPVAMHLDHGSSFGLAMQALRVGYTSIM
                     IDGSHESYEDNISISKSVVDACMPSDIPVEAELGKVGGKEDDLDGGDGGAYTDPLEAK
                     EFVERTGVSSLAVAIGTAHGLYKGEPKLDLDRLSEIRDVVSVPLVLHGGSGIPDEVIK
                     ESIKRGICKVNYATELRIAYSNGVKNVLNSDPEVIDPKKYGKKGLESVKDFVKSRMEV
                     CGCVGKAIETVKC"
     gene            complement(52705..54621)
                     /locus_tag="PC494_000241"
     CDS             complement(52705..54621)
                     /locus_tag="PC494_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIABC"
                     /protein_id="HDF3910773.1"
                     /translation="MGKKMILGVTGCPTGIAHTFMAEEALKNSARELGCDIKVETNGA
                     IGVENKLTAKDIEMADAIIVACDKNVDMDRFNGKPVIEVPVKEGIHKANELIQRCIDG
                     KVAIRKGNLSSSKIAEEGNLSFGQKLYKDLMNGVSHMLPLVVAGGVLTAISFLWGIYS
                     FDPNSEQYNQIAATLKSVGGYSMNLMVPVLAAFIAQSISGRAGMLAGLVGGMISFDTG
                     SGFLGGIISGFLAGYLVKLFVHLLRKLPRQLEGLKSIFIIPIVSVGLVGVAMLLLGGP
                     CSALNNAMMNFLSGLQNSSPIILGIVIGCMSAFDMGGPVNKAAYVTGTMLLGQGNYLF
                     MAGVSAACITPPLVIAIASTLFKNRFTEEDRAAGLINYILGSTHITEGAIPFAAKNPL
                     KVLPVLMIASSISSILTYIMKIEVPAPHGGFLVLGLVNKPLLWVGCIFVGSLVGAVLY
                     MMVTPKVVNEKNTIENTNATKDEHKNESAESENVSNNISLYSEETVILDVKGKNKTDV
                     IDEMIGILDKSGVLLDKKKFKEEILKREEISSTGFGMGIAIPHAKTDAVKVPRVAVGV
                     SKEGFDFESEDGSLAHIIFMIAATDNGDNLHLKTLSQLSSKLMNEEFLNELLNSKTSR
                     EIVSKLNNEEIKSV"
     gene            complement(54624..55544)
                     /locus_tag="PC494_000242"
     CDS             complement(54624..55544)
                     /locus_tag="PC494_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase family hexose kinase"
                     /protein_id="HDF3910774.1"
                     /translation="MIYTLTTNPAIDMNISTNGIKRKLVNRTSNAVYSPNGKGLNVTF
                     VLGHYGIESKILGFFGGFSGKYIVEESEKRGFDVLPTWVEDTTRINIFLNDGSDEFKF
                     VNSGSYVNEKQKLDMLDKIQSLEDISYLSISGSLPPGIDDNYYEDIFKICKNKSIKTI
                     LDISSPKLKELLQYNPYLIKPNDEEIKDIFGIIVRDEEDIKDVLKLLHLKGAQNILLT
                     LGEKGSYFYNGKLIYYASAQPVTVVSSACAGDSALAAFLSIWLENPEHIEEALKRSAA
                     TGASVAESNGIGNLENVEDYIKNIRVRKVV"
     gene            complement(55646..56398)
                     /locus_tag="PC494_000243"
     CDS             complement(55646..56398)
                     /locus_tag="PC494_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HDF3910775.1"
                     /translation="MIIELNKSNSENLTKTELEIIKFINENESILPELSIVEIAHETY
                     SSPATVSRAIRKCGLNGFNELRYRLTVKDENDDIQNMGDIINKSFIEAQRVIEQISLT
                     TLINIIKTINKSSKIYILARGLTEYVAKEFSLKLQLLDFNVVFINDPNIMKIKSKSIK
                     KDELIIIFSLNGNTIELVESAQNANLVGAKVITCCCSESAKLIKYSDLYIVGYKHEHI
                     SISEYEVSSRLPLYIISRIIIDYMVRYNNSEN"
     gene            complement(56790..58235)
                     /locus_tag="PC494_000244"
     CDS             complement(56790..58235)
                     /locus_tag="PC494_000244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HDF3910776.1"
                     /translation="MIKLGKFPKGFLWGGAVAANQLEGAWNEGGKGWCLADVHMYDKD
                     RDISKPYESDMTIERIKFAMKDKNGYYPKRSGIDFYHTYKEDLKLLKALGLKCFRFSI
                     NWARIFPNGDDLEPNEEGLKFYDNLINEVIDNGMEPIVTLLHYETPLNLVLKYKGWSN
                     RKVVDFFVRYAELILNRYKNKVKYWIVINQINLIHYESFNSVAFCVDQVDNVEEARYQ
                     AIHHQFIATALTKKLGKEINSDMMIGMMMADCTSYPEDCDPENVVFALKRNRLQYFFT
                     DVSFRGEYPVYIKRFFKENNINIVMEEGDDKILKENTMDFLALSYYYSTTVSASKNTM
                     NPTDNIKNPYLKANPWGWAIDPKGLYNTLSQYYDRYQKPIMIAENGFGMHDKFEDGKV
                     HDSYRIDYLGKHIEQIGEAIADGTEILAYCMWSPIDIVSCSSQEMEKRYGFIYVDIDN
                     NGNGSKERYKKDSFYWYENVIRTNGEELREK"
     gene            complement(58257..58610)
                     /locus_tag="PC494_000245"
     CDS             complement(58257..58610)
                     /locus_tag="PC494_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HDF3910777.1"
                     /translation="MTIEEHIIDEELVEVAMQIILRAGEARTEIKHALNDLEKFDYRN
                     ADLKLAKAKGFMTEAHRAQTKIIQGEAGGEKRAHSLLFAHAQDTLMTIFSELNITMSL
                     VGIVKSIEYKVNNSK"
     gene            complement(58639..59886)
                     /locus_tag="PC494_000246"
     CDS             complement(58639..59886)
                     /locus_tag="PC494_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDF3910778.1"
                     /translation="MGRVFMNKFIDFLSEKFTPVVNNMTKNIWVQSVQSTIMKVLPMV
                     FVGSLVTIVSVLKNYISFLPDLSPINQYTFGLLGLFIAFLLPMEIMKNKKFESMSVVA
                     GLAGAGLMLMMIRPEITNEGAIFNFNRFGGEGMLVSLVAGLFSGLIMSLFGSFSFFGE
                     DSALPDFVSKWFDNMLPITVIMFVGWGLIYGLNFDMFEIIVRVFKPVSDIAQTLPGFV
                     LLNFLVVFIYSLGISGWVLSPITYSIQLGAIAANAAAVASGGVATNIYVYEVIQTGWI
                     TLGGLGATLPLVIMMCLSRVGRIKAIGRACIVPSIMNINEPVIFGAPVAWNPFLMLPM
                     WIGTVVISITTYLSMSMGFVTIPSKVFNLWYVPFGISTFMVNQDVRGLIVLAINIVLL
                     FMIWYPFFKAYEKEEIKLESQEV"
     gene            complement(59894..60211)
                     /locus_tag="PC494_000247"
     CDS             complement(59894..60211)
                     /locus_tag="PC494_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDF3910779.1"
                     /translation="MKNIRVLLACGSGASTGFMATSMRKSAKKKGIEADIKARSESEI
                     DKYLSEIDCLLLGPHLDYMKEEIQQKANEYNVPVACISKTAYGRLDGAKALEEALELI
                     SNK"
     gene            60453..62366
                     /locus_tag="PC494_000248"
     CDS             60453..62366
                     /locus_tag="PC494_000248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDF3910780.1"
                     /translation="MKTSKKELFLNFIKTQHDWIDSSTLANYLNVSTRSIRKYVNEIN
                     SNGEFILSSKKGYKVNLNNNCQTKVDSSENISPDNRLNLILKELIVNSNGINIFDLSE
                     ELFVSPATIEGDIVKANKFIGSYNLKIKQSKFLLKLIGNESAKRKLMSSIIFKETGSD
                     FLSLFDVQKIYQEYNLTKLKENIIYILKKYNLFINEYAINNILLHLMITIDRIKKNNY
                     IESVEVVNYIDNNNDISISRDISNFLESEYNITLTSAELYYLVFQLTNKTTVLNYHEM
                     DTKSLPNYIDEHFVKLTKKIIKNVYDLYLIDLSDEEFVVKFTLHVKNLISRAKNNQVL
                     RNQIPQKLKDSYPLIYDISVYICNQIQTLENVDIDEDEISYISLHVGSFFDRQKLLED
                     KVLCALITPNYYDLQFKIVRDLEKRFNESIEIIQIFSDTHNLDFDNKVDMVITTLPIN
                     NRCPIPFVYVNPYLNRKDYDNIQSKFTQIKDRKNILTVQNHLEMYFSESLFMKNIYLD
                     SAKDYIKFMGNILYENKYVKPNYIDDVLIREKMSSTAFNNNVAIPHSMKMDALKTGVC
                     LIVNDKPVKWGEEKVQIIAMIPINEKEKEKFNYIFESFIEILSEWNNVKELTKADNYS
                     SFMNRIAYLIQNI"
     gene            complement(62489..63643)
                     /locus_tag="PC494_000249"
     CDS             complement(62489..63643)
                     /locus_tag="PC494_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HDF3910781.1"
                     /translation="MKILISIDSLKGSLSSIEAGNAIKKGILKVKEDAQVKILPLADG
                     GEGTVDALVQGMNGKKETIEVTGPIAKKVDATYGLLKNTSTAIIEIAQASGLTLVPTE
                     LRNPLYTTTYGVGEIIKEAINKGYRNFIVGIGGSATNDAGIGMLQALGFEFYDKNNKL
                     VGLGGKVLNEIRHIKIENRLKELDECKFKIACDVNNPLFGKNGAAYIYGSQKGATSEI
                     IEELDNGLRNFSKVVKNYLSKDVANVEGAGAAGGLGFAFLAFLNSKLESGIKIILEEI
                     KLEEELKDADFVITGEGRLDNQTAMGKAPIGVAKLAKKYEVKVIGLAGATTEDAVKCN
                     EEGIDAYFSIVNRAMTIEEAMDKATASENMTATTTQIFNLITSIQQSKNM"
     gene            complement(63922..66537)
                     /gene="mngB"
                     /locus_tag="PC494_000250"
     CDS             complement(63922..66537)
                     /gene="mngB"
                     /locus_tag="PC494_000250"
                     /EC_number="3.2.1.170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannosylglycerate hydrolase"
                     /protein_id="HDF3910782.1"
                     /translation="MKKNVHIVPHMHWDREWYFSTEESRILLVNNMEEIMDMLENNHN
                     YPYYVMDGQTAILEDYLAVKPECKERIKKLVQEGRLIIGPWYTQTDEMVVGGESILRN
                     LLYGIKDCDEFGEYMKIGYLPDSFGQSAQMPQILNGFDIKYSMFWRGCSERKGTNKTE
                     FNWKSDDGSSVLVQILPLGYAIGKYLPMNEDELRTRMDKYLPVLDKGATTDHIILPNG
                     HDQMPIQKNIFEVIYKLKECYPERKFFLSRYENIFKELEKNDDIDTIKGEFLDGKYMR
                     VHRSIFSTRMDIKSANARIESKITNILEPLASIAYSLGFEYHHGLIELIWKEIMKNHA
                     HDSIGCCCSDKVHQEIMNRFFLAEEKVDQLITFYKRRIVDAMSCEMALDKLVAFNLMP
                     YDRNEIVSTQVITKMKAFEIFDKDNNKLDFEVVHKEVIDAGLIDRQIVHYGNYDSFMV
                     YTINFKDKIPAMGYKAYMIKEVEHMLEKAYEVCDMVDNDFYTIQVNENGTLKIFDKKL
                     NKTFENVLLMENGGDEGDEYDFSPLPNEKLIFNDNIVANSTIKKNRFNNEIKINYRLK
                     VPKDIQARKNNRADSFIDFDIVINVPNDKAIIDVVFNINNQARDCRVRTYIPTNIASK
                     FSVSDNQFGHIKRSVYDDAMEVWQQEEWSERPDSIYPMLTFVGLSDKEHGVAVLTNST
                     REFEIVGEKFDTIAITLFRSVGFLGKEEMARRPGRPSGIKLPTPDSQMIGDIKIDLAI
                     VTHEKSTLEANVANMAKEYLTKIQTYNKMPYNAMKLNQSEIEVDYSYSLLKETNKDLV
                     LSVVKKAEKEEALVVRFYNSKEETKSANIVFNKNIKTAKWINLNEKELESISIDNNSV
                     NVECLMNQVKTILVK"
     gene            complement(66681..68606)
                     /gene="mngA"
                     /locus_tag="PC494_000251"
     CDS             complement(66681..68606)
                     /gene="mngA"
                     /locus_tag="PC494_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS 2-O-a-mannosyl-D-glycerate transporter
                     subunit IIABC"
                     /protein_id="HDF3910783.1"
                     /translation="MEFKKITNENLVFLKQKIKTKEDAIKFLARKLYYEGKLTSYEEY
                     LEAVMYRETLSPTGFERGLAIPHGKSKSVKEASFAAMTLETPIENWESVDPNNKVELI
                     FLIAVPENEGGNTHIQILSELVTRLSNEDYMNMLLNSKTKKELFNNLDIKEKKEQIKE
                     EIRIQNESKKIILAITACPAGIAHTYMSAEALIKAGKEIGVDVYVEKQGANGMVDPHT
                     PDIIKRADAIIYATDVAPKNTERFEHLPNIKTSVAAPLKRAKEIIYEALEVAQKQGKG
                     DYIEKSSDISYCEKSSWKKDVKSAILTGVSHIIPLIVAGGMILAFAVLASQAFGLQEL
                     YNQEGSWLWQLRKLSGGMLGTLMVPVLSAYMSYSLAEKPGLGPGFAAGLAADLIGSGF
                     LGGMLGGLLTGYIVKFLKKNIPAKGTLAGFVSFWVYPVVGSLVVGLLMLFVVGKPVAA
                     LNNGLINWLNGMTGVNAILLGAIIGAMVSFDLGGPINKAAYTFAIGAIASGNFIPYAI
                     FASVKMVSAFGVTIATVLGRDLFSESEKEIGKQTWILGLAGITEGAIPFMIEDPIRVI
                     PSLVAGSAITGSIVAFFNIGLQVPGAGIFSLALLEGSMSGFIIASIWFFAAVLGAIIS
                     AILLIITRKQKNQRKIH"
     gene            complement(68736..69461)
                     /locus_tag="PC494_000252"
     CDS             complement(68736..69461)
                     /locus_tag="PC494_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HDF3910784.1"
                     /translation="MEFYERAKKYEYKFTDTEDMIIEYMRKNKEEIVKLSIQSLADKF
                     FTVPNTIVRLCKKMEYDGFSQLKNNLKEELKNEDKEPKNGFESDIKKTLELIDYEKIN
                     KVADIIQKSRSIIVYGIGQNIPLCEILVKEIRGGHDNITYYSQRHEVLHDIGKLGEQD
                     MFFALSLSGETKEVIEAAKTAVNKGCKVVALTHICENQLQQIADISLYCYSTIKQVNG
                     YNISDKVPIMMIMRAIIEQYWLR"
     gene            complement(69724..70494)
                     /locus_tag="PC494_000253"
     CDS             complement(69724..70494)
                     /locus_tag="PC494_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ChbG/HpnK family deacetylase"
                     /protein_id="HDF3910785.1"
                     /translation="MKKLVVRADDIGYSEGVTLGIISSYKNGIVTSAGIMVNMPFSRQ
                     AIEMVKNDDVCFGLHVNLVIGEPCCKEHIKIKNLLDEGGKFVSSKIRRTQLLTGKEVF
                     NYEEVYEEVCAQIETYKLYMSKLPEYIDIHGIEEDVSISAMCDAAKEYGIPSCPYYLD
                     SCISMPSKYPQNDFYKLNKSFVKLFEEKYINLDKDITLMVTHPGFIDYSLIKSSSLIQ
                     ERVYEHAMLCDKEVKMWLKRNNIELVDFKDIFKSNNYI"
     gene            complement(70496..71923)
                     /locus_tag="PC494_000254"
     CDS             complement(70496..71923)
                     /locus_tag="PC494_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HDF3910786.1"
                     /translation="MMQQLSLLGKTMLVPIAVMPAAGILGLLFGPNMLNVPAISNISN
                     IVFSNVDYLFLLGAASAYSKSKDKTSVMVAAVVAYMIFKSNLELLNDTLNAGVFGGII
                     VGACIAWTYNKTYKVKVPAFLSFFAGEKCVITLSPVVALILSYIFSLLWIYPQAAMNQ
                     FGFWLGGAGAIGIFLFLFCNRALIPTGLHQVLNAYILFEMGEYTTSTGEVIRGEIPRF
                     MAGDPNAGFFWTGFYIIMMFSIPAISYAIYKTAQDKKKQEVKGAMTAGALTSFMATVT
                     EPIEFSFLFASPKLYIIHSFYSGLGGVVLYLLGVRLGSFNGASIIDYVLSFSYGDKAW
                     LVIPVGVVFFVLYYVTFKYIIIKDNVQTPGREVEIEIGDKVSEKEKNLKLSHGNFSYM
                     AKQIIKNCGGYENIVTLNNCMTRLRLEVKDATILNDDNIKKTGAKGVIKLSNTSVQII
                     IGTDVVKVKDEMEMQLDELRKQADA"
     gene            72314..73036
                     /locus_tag="PC494_000255"
     CDS             72314..73036
                     /locus_tag="PC494_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDF3910787.1"
                     /translation="MAKNKFSEIYEVLKEEILDGKYTSNMMLPTELQLIERFSCSRNT
                     VRRAISQLNTEGYVQSIKGKGVVVLENSCSNDFFLNMHNFKGVESIVEDKKVNTATSV
                     LHFSKILIDNKLSKKTGFKVGSEVYYLHRLRYIDNIPKILDINYFLCSIVKDLDVSIA
                     QGSIYKYIEECLGTKIVSSRKIFKIEKATELELKTLPLNDYNCVGVIKNSVYTDDGKL
                     FEYTESKHTPETFVFMDVTQRY"
     gene            73233..74900
                     /locus_tag="PC494_000256"
     CDS             73233..74900
                     /locus_tag="PC494_000256"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HDF3910788.1"
                     /translation="MKNWWKKATVYQIYPKSFKDSNNDGIGDINGIIEKLDYLYSLGV
                     DLLWLTPMYVSPQRDNGYDIEDYYNIDPKYGTMSDFEKLLKEAHKRDIKIMMDMVLNH
                     TSTEHKWFKESKKSKDNPYRDYYFWKDAKPDGSVPNNWISRFSGTAWKYDETTNQYYL
                     HLFEETQADLNWENEKVREECYKILEFWADKGIDGFRLDVVNLLSKTPGLPDDPITGP
                     KGDGRTHYADGPRIHEYLHNMNQKVFKPKNIVTVGEMSSTTPEECINYTRENREELSM
                     VFSFHHMKTDYKGGAKWTNEMFSLDKLKKAQSDFQYKMYEGKGWNALFYSNHDQPRAL
                     SRFGDDRFFRQESAKMLAITLFGLQGTTYIYQGEEIGMTNAYFTKIDEYDDAESKNAY
                     YHMIKSGIDEKEALLILQQKSRDNARTPMQWDNTIYKGFSNHKPWLKVNNDNISVENE
                     LNDSRSVFYTYQRLIKYRKQYDIFTEGTYRLLDENHKNLFVYEREYKNQNLLVISNFT
                     HDNVVYKLPETYLNKLNYTILETNYTRDIIENKMEIKPYESIMIYYK"
     gene            complement(74996..76315)
                     /locus_tag="PC494_000257"
     CDS             complement(74996..76315)
                     /locus_tag="PC494_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HDF3910789.1"
                     /translation="MEKGIKLGFWSIVLLGINAIIGSGIFGLPGDAYTDIGPASILVL
                     VFCMLLAVSIALCFAEAGSWFDTDGGPYLYAKEAFGDFVGFEVGFMKWIVSMIAWATM
                     ANFFAVTLSSVWPQVAEPLIKNIIIGILVVGLGIINFMGMKQSKHLNNIMTIGKLLPI
                     VLFIAVGLFFIKGSNFTPFVIIQKGQSASSAFVAVSITLFYAFTGFESLAVAAKDMEN
                     PKKNVPKALVMVMFVVSVIYMLILGISIGVLGNGLAGSATPVADAAIKMLGPIGGYII
                     TIGTIVSVGGINIASSIFTPRSAAALVEQGLMPKSIRKTNKNGSPYIAIIVSVIGTLL
                     IAWSGSFTTLSQISVVSRFIQYIPTCLAVLILRKKYAGKDVNFRIPGGAIIPIFAVII
                     SILLLIKAGIDEPMKIVWGLGGMIIVVPIYFYMTKVYSKKYNDVEVK"
     gene            complement(76356..77102)
                     /locus_tag="PC494_000258"
     CDS             complement(76356..77102)
                     /locus_tag="PC494_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HDF3910790.1"
                     /translation="MKKLAKKKYPIIGISGNLLIDEGGMFPGYERAYVNNDYIQSVVM
                     CKAIPYIVPIVYDDEIIKEQVSNIDALILSGGQDVNPLIWKEEPHNKLGAISPKRDSF
                     DMKLLKHALDMKKPVLGICRGEQIINVTEGGSLYQDLSLIEGAYIKHNQQHLSNVPTH
                     TVQIKEGTKLYEILGEKEVLVNSFHHLVVNKVAPGYIVSATSKDGLIEAIEKEGSEFV
                     IGIQWHPEMMTRDYDNMKKIFMAIVKEASK"
     gene            complement(77346..79355)
                     /locus_tag="PC494_000259"
     CDS             complement(77346..79355)
                     /locus_tag="PC494_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDF3910791.1"
                     /translation="MKTIAVVTDGLSKLECFLNKNLEMIFKDKVMIKNYYLNKITEKE
                     LIKDDIILVMIDDRVLKIKKYVEDVSKIITINRSIKQKDIYKLFSLPEGIDVLVVNDN
                     KHTVLETISNLYNIGINHLNFIPYNPNEEYRNIKIAITPGESSLVPKYIEEVIDLGHR
                     YIDSSTFIQIIAKLKLDDKEITERLIKYTDEIISLYSGINTKYKELTIKADELNSIIN
                     LSNLGMAMVSDKGNIIICNNSLRDILDIQSNIIGKNIDELENENIKKIFSLSKAHDEV
                     IKFNNKYLNVNKYNIESFGRVTGYYFCIQEITYIRKLEQNLSKKLREKGQVARYTFDD
                     IKTVSTKMERTKKLGMKIAESDYTILITGESGTGKELMAQSIHNASPRHSQPFIAINC
                     AAMPENLLESELFGYEEGAFTGALKGGKKGLFEQANNGTIFLDEIGDMPIYLQSKLLR
                     VLQENQVMRVGGENVIDIDVRVIAATNKNLLEMIKGDRFRADLYYRINVLPINIPPLR
                     ERKEDIEVMLKHFMKRKRAISQDVQDIINAYEWPGNIRELKNTAMYINIMSSEDVILI
                     NDLPHNLLNITEDFSKEISILKDRTSIEKVKLVMECLKNANNLNKNIGRNGIVNSINE
                     LGYNITEGEVRGILNMLKELDLIICESGRKGSELNRRGKNILNSI"
     gene            complement(79749..81182)
                     /locus_tag="PC494_000260"
     CDS             complement(79749..81182)
                     /locus_tag="PC494_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HDF3910792.1"
                     /translation="MALRKDFLWGGATAANQCEGAWNLDGKGPSCSDMCTGGSQKVSK
                     RITRVIEKGTFYPSHEAIDFYHRYKEDIALFAEMGFKVFRFSIAWTRIFPTGMEKEPN
                     EAGLKFYENVIDECLKYNIEPLITISHYEIPFAITEKYNGWVSRDVIDLYMNYCETIF
                     KRYKGKVKYWLTFNEINSATMPMGGYLSQGILNEGTTDFINQVDIPQLRFQGLHHQFV
                     ASAKAVKLAHEIDSNYQVGCMQIFATMYPYTCNPDDAVKTQRDSRVMNYFCGDVQVRG
                     EYPTYMNRYFGENNIEIKMEKGDLEILKEGCVDFYTFSYYMSTCVSSDSKEDNTSGNI
                     LGGVKNPYLKSSEWGWQIDPEGLRYALNEIYDRYRIPMMVVENGLGAYDKKESNGVIN
                     DDYRIEYLKAHIEQMKEAVEDGVDLFGYTPWGCIDLVSASTGEMAKRYGFIYVDKYDD
                     GSGDLSRIKKKSFDWYKQVIESNGERL"
     gene            complement(81269..83185)
                     /locus_tag="PC494_000261"
     CDS             complement(81269..83185)
                     /locus_tag="PC494_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HDF3910793.1"
                     /translation="MRKYEQLSKEIIANVGGKDNISSLSHCITRLRFKLKDESIANDD
                     VLKKMDGIVTVMKSAGQYQVVIGNHVPDVYEVVCDLAGLGGDTIDNSDSDAPKGLLNK
                     FIDIISGVFQPILGVLCAAGMIKGFNAVFTALGLYGETDGAYIMLNAIGDAMFQYMPI
                     ILGYTAAKKFKLKPFIGMLIGAVLCYSGIQLDTLASTGQPLYNLFTGTIFESPVYITF
                     LGLPVIAMNYTSTVVPVILIVLLVAKLEKVFAKIIPDVVKNFFVPMAVLLVSLPLGFM
                     VIGPIATYASNIVGNGFLALFNFSPILCGALTGLLWQVLVIFGLHWGLVPIAMSNLMT
                     MGFDTILVGAFVPSFAQTAVVAAMYFKLKDKKIKELCIPAVISGICGVTEPAIYGITL
                     PRKTPFIYSCVGGAVAGAVMGIMNVKSYVMGGLGIFGIPNYINPTTGDMKGVYATIIA
                     IIVAIVVGFVLTLFFWKDDAIVEISKDDNGQGVIEKNKREVVYSPIKGEVKALEQIQD
                     AAFSTGILGKGVAITPKEGKVVAPFDGTVMTLFPTKHAIGIISDNGCELLIHIGLNTI
                     QLEGKYFKSFVNQGDKIKKGQTLITFDIESISKEGYCLETPVVVTNYSDYVDIVENTQ
                     KHVNNSQKLITVLA"
     gene            complement(83259..84119)
                     /locus_tag="PC494_000262"
     CDS             complement(83259..84119)
                     /locus_tag="PC494_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HDF3910794.1"
                     /translation="MIIEKILNNNVIITTDENHKEIVVMGRGLAYKKRTGEHISKDKI
                     DKIFKLSDPNISDKFKELIADIPIRYMELSDEIILYAKEKLGKRLNDSIYISLTDHMY
                     TAIERAREGVSVKNVLLWDIKRFYKSEFKIGLEALDYIEKKFEIRLSEDEAGFIALHI
                     VNAQMDQSIKTIYEITQIIQEISNMVKYHYRIVFDEDSVYYHRFITHLKYFAERIVSN
                     NLHENNEDDLLNVIKVKYKNAYKFIEKLDEFIHKKYNYDLTDEEKLYLTIHVERVVSK
                     SIKSDINPNN"
     gene            complement(84470..85657)
                     /locus_tag="PC494_000263"
     CDS             complement(84470..85657)
                     /locus_tag="PC494_000263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HDF3910795.1"
                     /translation="MIESIKKRAYEIENGLGKEIEEVCNFIFNNPELGEEEYISSKYL
                     VEKMKEYGFDTVYPYCNMETAFRAELGDNDGPTIAFLAEYDALPGYGENKEPAHACGH
                     NWIAASTLGACIVLSKLKENFKGKIVLIGTPAEETTGGKCDLVKAGAFDDVDVSYQMH
                     IEAFNNINCKALAIDSLEFSFEGVSAHAASHPHMGVNALDAVQLTFAGINALRQHVKS
                     DVRIHGIVSNGGEAPNIVPEKAACKFFVRAAERSYLDEVTKKVINCAKGAELMTGAKL
                     SYRYFENSFDNIINNKVLQKITKNNLIEAGITDILEGKDGPVGSTDIGNVSQVCPTMY
                     TEIALDISPMVYVHEKEFLNYANSEEAYDKLHKAVKAMVGCALEIYLEDGLLDEIKKN
                     HLN"
     gene            complement(85671..87062)
                     /locus_tag="PC494_000264"
     CDS             complement(85671..87062)
                     /locus_tag="PC494_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HDF3910796.1"
                     /translation="MSSLKKKKFTMPQTLTIIFLLIVLMAILTWIVPSGNFERVDIDG
                     RSVVVAGTYEKAPSNPQGITDVFTAPINGFIDAAEVVGFVLIVGGAFGIVNKTGAIEA
                     VIAHTVNKMKKFQFLIIPISMILFGLGGTTFGMSEETLPFYMIFIPLMTSMGYDSLTA
                     VATVFIGATAGFGAATTNPFSVGIAQALSQIVPGSGIEFRVVMFIIYMAISIGFVMMY
                     ANKVKKDPKKSLVHDISLNQELMVNSDTNIKEFTKREAMVIAIFTIGMAIMIYGVLRL
                     EWYITEIAMIFTAIGIISGIASGLKQDEIVNSFISGAGDLITAGLCIAFARGIVIIAE
                     NGFIIDTILNSAANLLNGLPKTIFINLTFLIEGLIAFLIPSASGLASLTIPVLAPLGD
                     LVDVSRQMIVTAYQFGIGVTNLITPTSGVLMGALAVANIPWSKWVRFVIPLMVVLTIL
                     VMAFLTIGLYLGF"
     gene            complement(87657..89357)
                     /locus_tag="PC494_000265"
     CDS             complement(87657..89357)
                     /locus_tag="PC494_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HDF3910797.1"
                     /translation="MHYIAWHFNKNGGNNTMKDKLQVLSGAMMIPVILLVVAGVFIGL
                     GSAFANMENVSALGLSGLIKEGSFINVFFKVINDLGFMVMRYLPIFFVTGIAFGLSKK
                     EKGWGALGGIVLFIGMHTVISTLLAANGINSDTVTAEAFMASGLGEAEAYSRSSLYGS
                     FLGIFSYDCSIFGAIIAGFVASAVHNKFVDIELPSALSFFSGPRFSMIMMFIASIVLG
                     TAMYFIWPPVGLALSKLGNWIGSSGLLGTFTFGAMDKALLPFGIHHLIAFPIEYTRVG
                     GTMEVGGAIYEGVNNIRLAQMGDPDTLSYITRNFTTGRLLIHFAILPAAALAMYKLAD
                     NANKKKAISILIPAIVTAMLVGVTEPIEYTFLFVAPLLYFVAYVPLAGLTYVFTEMFN
                     VSIMGESFRNMFPNLLQPQKVDALPLLFLIPIFFIVTYIIFTWAIKKFDIKTPGRSSE
                     EVKLYSKKEYRERQSVDAGKTAYNNAVEEEVDDKDTKLVHSIIEGLGGSNNIKNVTNC
                     ATRLRVELNSIDGFYEDGFWVNELGASGVVKKKNSVQVIFGPRVITIASKLKAVLGVD
                     "
     gene            complement(89329..90732)
                     /locus_tag="PC494_000266"
     CDS             complement(89329..90732)
                     /locus_tag="PC494_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HDF3910798.1"
                     /translation="MIVNKELIIDYLKSNQENIINDIRSLVEIPSIRDESTTDINQPF
                     GIEIRNAFDKLIQIAKDKDFVVKDFDGYAIHIEYGEGEEVVGVLNHIDVVPIYNKELW
                     KSKPFKVCQKDNYLYGRGVNDNKGPLIGILYALLFLRELNEKPKRKIRLIVGGAEETT
                     WECMEHYFSVNEQPKFAFSPDGNFPIVNGEKGILYFNLRKKIDKDKFRNHNLVDIKSN
                     KEDGFVCNKIEAVFKTNDKKDLVESLAYYTEIEELEEGKVLVRYTGERALSRNPHRSY
                     NCAFSLAKDLEKIKKLNDKGVIIRDILNSYFTDDNHGKKLGIYKEDVDMGVSTICIMS
                     IFLEKNELNMKIDFRYPKGISWEFITNRINEIGKKENLIVDIYKDLKLLYVKPDSELI
                     NKLSNAYKQGFGKEAELFTKGAASYARVLKNGVAFGPTIEGDNPNSHQANENISIDTL
                     YKAIEVYIYALYSLAFQ"
     gene            complement(90996..91487)
                     /locus_tag="PC494_000267"
     CDS             complement(90996..91487)
                     /locus_tag="PC494_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HDF3910799.1"
                     /translation="MFNIFKKKENKIEKIYSPFKGNLVNLEDVPDAVFAQKMMGDGVA
                     IIPSEGKLYSPVDGEIVNVFDTKHAIMIKSNDNTNILIHVGLETMSLEGKPFDVKVKA
                     GDKVKAKDLIMEVDLDFITSNDLNIITPVVIMDDADSVKRTVKDRIEPGNVDINSIIM
                     EVE"
     gene            complement(91513..92325)
                     /locus_tag="PC494_000268"
     CDS             complement(91513..92325)
                     /locus_tag="PC494_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HDF3910800.1"
                     /translation="MRYKLICTDMDGTLMGKGFEVSEENIKALKEVMEKGIKVALVTG
                     RPYNAMKYFTSVLGDDIYIISTNGTYFKLLGYEYKKVLSKETLKKIYTIGEKYNLNKH
                     FKGCKIVISNNEIGEEHPYRLINSKNKEEDRIEIIENASCETLLEKADNEILKCILFS
                     ENVDSLREAKEEFKKQEDLEVVSSGKINFEVMSKGTSKGIAVKKFCDILGIDSEEVIC
                     IGDNENDISMIKFAGLGIAMGNATDEVKSMADFVTDTNVNDGVAKALRKILS"
     gene            complement(92338..93489)
                     /locus_tag="PC494_000269"
     CDS             complement(92338..93489)
                     /locus_tag="PC494_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HDF3910801.1"
                     /translation="MINFYQPSRINFGQGTLSELPRIIGKYGKKCLLVTTPNVEPLDK
                     LYKRVTLNLIEKGIEVVHFDRVEPNPTVELINEGFELAKKESVDVVLAVGGGSSIDTA
                     KVLALTFGLEKIDWDYMFSTYTNPFKIYDKVSEKELPLIAVSTTSGTGSQVTQAAVIS
                     RGSEKNTIFHQNCFSKECIVDPELMLTLPERITASTAFDAFTHAFESYINPNANDFTE
                     IMSEKSMELVINYLPKVMEDKNNIEYRTKLAVADTLGGSSLANAGAAAPHPLSEIIGG
                     VTHIPHGEALAIVFPKFAEKFYKDNIEKFAKVARMLNQELEKVEDDEAAKTLGNEIES
                     FLKRVGLKTKMSEFNVTKEQLEQITSCPVLGFLPFGKKEDLVEILEKSY"
     gene            93759..94400
                     /locus_tag="PC494_000270"
     CDS             93759..94400
                     /locus_tag="PC494_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldolase"
                     /protein_id="HDF3910802.1"
                     /translation="MKYLIDSANLDEIQKCLKYGFKGITANPSMYLKEKVNFHEFIET
                     CANLNPEILTAEVIGNNLYELINSCDKILNINKNTIIKINFSEVGLELINILNSKGVK
                     TACTLIFNVNQASLAINAGADYLFPFIGRNDENGNDGIKNLTEICNLISINGYNTKVV
                     AASIKNVFHLTQASLCGCDYAAVTYDLFKKASFNQLTIDGANTFERDWSKVNK"
     gene            94426..95970
                     /locus_tag="PC494_000271"
     CDS             94426..95970
                     /locus_tag="PC494_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HDF3910803.1"
                     /translation="MNKRLLDIAELLLNSSDYITVDTIAEELKVSNKTIRNDLVILDE
                     WLLEFNLSLDKKTGSGVIILGNEDIKLKVIRDINDKSNCIYAYSPEDRKRYILSKLFI
                     KNSKFRIRDICNELHVSRATVHKDLVVIQNFLQNFKVTLVRKTNNGVYLEGKEKDIRK
                     AIFELATVNKSYTELKEILFSKSNECKDTPSTKIFKELFNYDFEKLSQITLHTLQVEK
                     SNLSDEYYINFLIHIAICIKRISIKRYINLSEGFFRELLEHEYFEKSKILCANLSEAF
                     DVEFIDEEVCYILLHIEGLLKSIKKTTTLEPLKNEEITEYNLSEAIAVHWGSILNLNL
                     KDDLILIKSLANHLKSVLHRINYGFTITNPILNDIKRTFPYTYKAAKESNTVIKQLMN
                     YEVNDDEIGYLALYLISAIDRSKSPLNTILICHCSDGVSNLLVQKLSFEFNQINIVKS
                     IPLSSISFTNFDDVDLILTTAPVDFEHNAELININALLSKNDISRLSTIIKKLYSEKN
                     KILSYK"
     gene            complement(96170..96796)
                     /locus_tag="PC494_000272"
     CDS             complement(96170..96796)
                     /locus_tag="PC494_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HDF3910804.1"
                     /translation="MKKEMIKDYLLITISAFLMALAVNFFFAEHTLAPGGITGLSVVL
                     STFLSMPVENISLGISMPLLVMGLLFLGKGFGIKTLYITLMGPLFLKVIPQTHITDNL
                     LVAGVIGGLLVGTAIGIAIIRGCSTGGTDLVAMLINKVIKFLKLPVILFMLDGFIIVA
                     SGIISKNFMISIYSLISLLLIIKTIGFVTTKFGKNTEEINNINNACAQ"
     gene            complement(96931..97647)
                     /locus_tag="PC494_000273"
     CDS             complement(96931..97647)
                     /locus_tag="PC494_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentose-5-phosphate 3-epimerase"
                     /protein_id="HDF3910805.1"
                     /translation="MKHIKIAAGLAHVNYGHISAVVKEAMDAGVDYVHSDAADMHDLK
                     NMQLMGGHQIIEAIRPVTDKPIECHIYTRDCDRLFIEKIAAAGCNLLIIPAEHFLGAP
                     LAYIINYCREFGMKVGLTIGCYTPLCFVDEAIYDIDRLQIVVHGVDETDGKDNWGWRK
                     SAVDLVKRARKMIDEKNPKCELAIDGGLRSDNMEPLIECNPDVVILSSAIFKDKDGIT
                     AGVKNCRKAIDEAATKFGLE"
     gene            98073..99287
                     /locus_tag="PC494_000274"
     CDS             98073..99287
                     /locus_tag="PC494_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HDF3910806.1"
                     /translation="MRNCIIAQSGGPTAVINASAVGIYEKNLETKYFDKVYFGINGIE
                     GILNKNIIDSDSLNKDNVLNLKQTPSSGLGSCRYKLADYKINSYDYDRVINILDEYKI
                     DTLFYIGGNDSMDTVMKFSQYCKNTTCKIKFIGIPKTIDNDLLGTDNCPGFGSAAKLI
                     STLIMETYLDFSIYKNNGIFIVETMGRDTGWLAASSSLARLNDTPLVDLIYLPEIDFY
                     EDKFIEDVRKIFKEKNKAYIVASEGIRDKYGNFICEQKTSAHDKFGHSQLGGVSNYLK
                     NLIVSSSITTRVKTLELGVIQRCAMHLASDTDLKQAAEVGAYGIELSKKGYTGVMAII
                     NRTCNNPYKYEVSHTDISKIANKTKYFPKEWINEECNYITNEALNYLYPLIQGKPDIK
                     YKNGLPYFSIIY"
     gene            99905..101233
                     /locus_tag="PC494_000275"
     CDS             99905..101233
                     /locus_tag="PC494_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3910807.1"
                     /translation="MMKIAVITTEFLKEFVDNSIKKLNINAEIEIYIYRDFSHVGDLY
                     LEIEDRFDGFAVSGPIPKKAITKKAGTIKKPLVDFGTDLQSYYDMFLKLIFKYNTLDF
                     SRAYFDLTDWADNPKDISYYLSNGTFGDLMDSIDENASKMSLSDIAKLEKKIAKKHIN
                     LWNEGKIDFSTTRFSSIVPMLQNAGVNFHFIYPDIDLLKNTFNNLIKDIHLHRMKGNQ
                     PSVIYITVKDTNYDDSTLDQVYKILNSIKKDKLTDFIIEKNSNSFKIFTKCETIKSLT
                     KNFTACYIKESIENSTNIKVCVGYGIGNDIKQAMSSAISANKESKINHLNYSFLVNEN
                     YETIGPLLCDKLLTVSNKVTPHINTIAKSSKLSTLTIQKIISVTEILQRDEVTPKELS
                     SCLNVTVRTANRFLSSLLKSGNATILYEKQNSTKGRPERVYKLFISENKY"
     gene            complement(101361..102551)
                     /locus_tag="PC494_000276"
     CDS             complement(101361..102551)
                     /locus_tag="PC494_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HDF3910808.1"
                     /translation="MKNFFKEAQSIEGEIIRWRRYLHENPEIGCNIPKTVTFVTSTLE
                     KMGYSPKLTSNNGIVAVLDSENGGKTLLLRADMDALPIMEETDLPFKSKNKDASHSCG
                     HDNHTAMLLGAAKILMDNKHLLKGRVKFVFEPDEETTRGAKSMIDDGILENPQVDAAM
                     AFHSMVGKFLNTGQVAYSRGPAMASADIFEITVEGKATHGASPEFGVDPINIMSHIQI
                     ALNTILSREKPQKEPVVLTIGMFNAGNVPNAIPNKASMSGTLRTFDQFVREKLKNRII
                     EISTGIAKSFGGNAKVEFKMGTPAVINDLDVGDEIVSYVKEVIGNENVIDFPSAMGSE
                     DFSEILLRVPGVFLWIGMGSISQGYNFGMHNPKAIFNEEGLVYGSALFAHCAVKWLEN
                     NFSR"
     gene            complement(102657..104036)
                     /locus_tag="PC494_000277"
     CDS             complement(102657..104036)
                     /locus_tag="PC494_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HDF3910809.1"
                     /translation="MIGSISINEIDKKRFKLDDLSKKIWENPEKAFKEFKACENTANF
                     LRSEGFDVEVGVGGLATAIRASFGSGKPVIGFMGEFDALPGLNQKVSTKQEAFELGAY
                     GHGCGHNLLCTAHVGAVVGLKREMIENNLSGTIVFYACPGEEQLTGKGFMARGGAFEG
                     LDLAINFHPNKISEATIGTSTAVNSVKFHFKGKTAHAGSDPQNGRSALDAVELTNVGA
                     NYLREHVTSDVRIHYTITDGGVAPNIVPDKASVWYYTRALSREAVESTYERLVKVAKG
                     AAMMTETEVEVEFLGGCYNTLNNHVLANLVSECMNEIKQEPWTREELDFAAELDRQSP
                     QQYKAMISKYNLPEGTHLYYGGGNVTNFNSYGSTDIGDVMHIVPTAYFFTGCTNLGAP
                     GHSWQFTSCAGSSIGEKGMIYASKIMAMFGAKILNNPEIAKKAKEEFDKSMNGKTYKC
                     PIPDDIPTP"
     gene            complement(104067..105275)
                     /locus_tag="PC494_000278"
     CDS             complement(104067..105275)
                     /locus_tag="PC494_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3910810.1"
                     /translation="MENFWNPLTCFTVCVMIYAFSEFLSKKTKGAISTLLFVCIIFLI
                     GFWTNILPKDITGASGILAAMSNFGIALLITNLGTLINLEDLCHEWKTVVIALVGIVG
                     IGVGCLTVGSMLFGREYALIAAPPIAGSTVAGIIVTTVAEAANRPELAAFVILVLSFQ
                     KFFGIPITTYCINKELKFKRDNGDFLKDESKSNFKLPSMRIFKEDLGKKSSTLVYLAK
                     LSFVAMIGNFVGLATLIPGFTPANYYLNPNIACLLVGLIFTRIGFLEKGILDKSQSNG
                     IIMFGCMLMLPGGLAKVTPTALFGMIVPTIGILVVGSVFIILFTAIVGKLLGYSPRMS
                     AAIGVTCMLAYPATQIISNEGIDAMEGTEEEKQRATDYLLPKMIIGGFVTVTIASVAF
                     ASIIGPIIFG"
     gene            complement(106300..107754)
                     /locus_tag="PC494_000279"
     CDS             complement(106300..107754)
                     /locus_tag="PC494_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HDF3910811.1"
                     /translation="MNIKDTFFWGGSIAAHQCEGSWDSDNKGPAIMDFVTKGSYETPR
                     VITDKIEEKLDYPSHNGIDFYNRYKEDIALFKEMGFSALRISIDWSRIFPNGDDENPN
                     ELGIKYYEGLIDTLIENNIEPIVTLYHFELPMNLVHKYGSWNNRKLIDLYLKYSETVI
                     RRFDDKVKYWVTFNEMNHIDPQTEHSDIFTYMIAGIKYSEIENKVQTLANVGYNMTLA
                     GVKVAKLAREINPNNKVGCVFGLNPIYPYNCNPSNVLNAFLDNDRDYYQIDAMCNGKF
                     PQYKLKEYEKNNITIEVTDEDKKAFKEGKLDFIGLNYYFSSVSTPKENLSGDKSLFGG
                     IQNPYLEQSKWGWAIDPIGLRFTLNYIYRKYQLPILITENGLGAYDKIEEDGTINDDY
                     RIEYLSKHLSQMKSAIEEDNVECFGYLMWGPIDLVSATTGQMSKRYGFIYVDLDDEGK
                     GSFKRYKKKSFDWYKEVIKSNGEVLDFSTDIVVG"
     gene            complement(107774..109645)
                     /locus_tag="PC494_000280"
     CDS             complement(107774..109645)
                     /locus_tag="PC494_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HDF3910812.1"
                     /translation="MKYKDLNENIIKLIGGKENIKSVAHCVTRLRFTLNDRSIAQTEE
                     IKKLKGVIDVVSNDVAYQIIIGTHVVDVYNEFMSMIGLSSSESSIKSERKKGIRGIKG
                     IFNSIFVVVSETMTSVIEVLLAAGILASMLALLNMSGILQSDSPTYQILDTLRSATFH
                     FLPVLIAIASAKRLNVNPYIAVVLAVTLLSSSIDGVEGLSLFGINLQATTYANSFIPI
                     LLGVWAMGIIIEGLKKILPKALHYFLVPVLSLIITLSITLTVFGPIGMWIGDGLNYAC
                     MFLIDTLGNWSVVALYAALQPLLIVFGAANFTMPISLNSVTTLGYDPIFMGAATISDI
                     AVCGAMFGYFLKTRNKEQKQLFGTVSFSALMGVTEPSVFGVFMKYRRPFVAVMIGGGI
                     GGLIAGLAQVKTYGMVWGLAALPTYLVGGEVSNFTFMIISVVVSFVAATAASYLLGIP
                     SDEKEEVKGDNEKELELIINENNSRTISIGNVAKGQVIALGEVNDKAFSSGALGKGVG
                     VIPSESKSTVISPVDGTITIVFPTKHAYGIVTDEGLEILIHIGIDTVNLDGKFFESLV
                     TQNQRVKKGDALAVFESDKIIEEGFDSTIITVVTNTSDYLDVISSNDESEELLTVIV"
     gene            complement(109635..110495)
                     /locus_tag="PC494_000281"
     CDS             complement(109635..110495)
                     /locus_tag="PC494_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HDF3910813.1"
                     /translation="MKIIQILNNNVALVKRGKNEIIVFVKGIGFKKRVGQVINENEIE
                     RTYILDSYDMLEHFSYLLQNSDSNNIVLINEIIEYGEKALNIKSSDYLSLTLLDHLEF
                     LLKRCEKNQFIKSPLVWNVKRFYPKHFEIGMHALKLIGDSKGLNLPDDEAVSIALHFV
                     NMEVNKESHDSTIVELRTLADIVSIIKYHFNVELDETSTNYMRFTTHLQYFIQRIMSD
                     EASIDEDNSIDLYKQVSQLYPKSFGSVQKIRKYIKSQFNVDISISEETYLMLHINRVT
                     QRLEAKSDEI"
BASE COUNT        36366 a        19642 c        11888 g        43099 t
ORIGIN      
        1 tttttatctt aatcttctga atataagtga atgctatcat tttaagtatc ttataagcaa
       61 tgtaactata tatctctaat aactactttt ttaacatgct taaactattt ataagctatt
      121 atatttatgt attaacctaa taactttttc actaaaaaat aacaatctat tcaaagataa
      181 actatagtac ttcttctact ttgtttcaat aaaatactaa ataaatttcg tacatccaca
      241 atttttcagg ctacactata aatatacaat atttatctta gttataagtt taagaatatt
      301 tttagtctta ttttgtcgaa tatcttttta ataaaacttc ataattctaa gcatattttt
      361 acactgtgtt ttcatgtaca aaaataatgc ttacaaataa acaacataaa taaaacttaa
      421 ataagatgga ttctattcaa catagtatcc atcttattca ttcaaaacct aaaaggattt
      481 tttataatat tatatatttt aaaatctaag taactcatta tagtatcaat ttcacttaaa
      541 gcttacaata cacttattaa tcttgtttta tattaaaaac atctacaata acaatttaaa
      601 tctttaagtg atatccatct cacacctaaa ggagtaggct ctccgcacta ttctgtaatt
      661 cttcaataca atcattatta ttttttatat aatttaatta tatattttat tttaccaaaa
      721 ccagcataca taaataatac ttaaaataga ttaaataaag gatactaaaa cactttattg
      781 aggtatatga cttgaaatat atgaactaac ttcattagga gaaatatcta aaatagttgc
      841 aaattcttca tttaataacc tttcagcttc tttcattata ttatcatctg cttgatgtgt
      901 ttttttacca atagatttta catactctct gttattatct atacttctta ctaattttat
      961 taactcttca catttaccac ctctgagtat ttttttaaat tgctcacttc tcaatttttc
     1021 attatctatc catgatgtat ccatattagg aatatcattt attaatgaaa gcacattaat
     1081 tttagaaagt aactttctca ttggtacttt ttcattatct acaggaattt ttattactgt
     1141 attattagaa taaataggac tcaatacata atactctttt tttattccat ttgtaaatcg
     1201 ttcatttgtt atatccatga ctttgcagac tcctgtcata ccatacatta tataatcatc
     1261 aatcttaaac aaaaacatca ccatccttaa taaaaaaaat agttttgaca actaaatcca
     1321 ccttgccaaa actatctgct atatattata ttttaacaca ttttgagact taaatgtaag
     1381 taaaacttat attattaaaa ttaaaaaata cattaaccat tgattaatgt attttttaga
     1441 tttttataac aagcatatca aaataaatta atacagctta tctcctgtga atacctataa
     1501 aattggtgct tggctattca ttgagtaccc atcatttctt acatcattta tttctaatat
     1561 ttcatcattt gttttaacct tagtaagttt tttaactgct ccataaggtt cttttaatga
     1621 aattttatct cctcttccag aaataaccca taaaattttg taccctctag gtattacttg
     1681 tagtttattt tcacctttac catcagtaaa gtagactaac aaattaatct ttttattatt
     1741 agcatactca aagactggag aaaatctagt acctccacct atcctaattc tatcttttat
     1801 atctttttca gttctcactt tatatacacg tctaatttca ttatcacatt ctataattgt
     1861 aatttcatga ttatagtttt tcactatact aagaacttct ttaatagctt gtttaaactc
     1921 ttcatcacta atacttccac ttacatcaag tgcaactgct atttctgact tatgacttct
     1981 aagttctccc ctcaaatcta aacgatttgg ttgtcttcta tttcttcttg ttatagtctt
     2041 ctttttatta ttttcaactg ttcccattat tctattaaga tataaattcc atggcaattc
     2101 acccttacta tttttaagtg atgatatcat actttctaaa taagcaggaa ctttaccttt
     2161 ttgagaactg ttaataaatt tttcagtaaa ttctctaagg gtattttcat ctatctcatt
     2221 ggattcatcc catatatcat gagttctttc ggggctataa tcaatttcta tatctccata
     2281 tttatcacta tcatcttcct caccatcttc ctcaccatct tcatccactt ccatcaaatc
     2341 taattcagtc tgaatctttt ctacataata ttcaaaaggt tcatatggtt caagttttaa
     2401 ggaatatttt aaatttaccc actctaaggt agttgcatat ggtggtaaat tgtttagaaa
     2461 tttatttact actatatcca ttgccatatt aattgctaat gtactatact ttccttttaa
     2521 ctcctttgct ctcatcaaat gcatagataa tatatgatga atttcatgtt taattgtagt
     2581 ctccatttgc tttatgtcaa gcgttaaaaa gattattgga ttaaaatata taatatattt
     2641 agctccctta aaattcacac ctgtaggact acttatatca aatcttattt ctcttgacat
     2701 ctgaaacaaa aaatatccat aaaaattatc ttcttcttcc ataagactta aattcacttt
     2761 atctacaaga ctaaaaaact catacttaaa atcttgtggt atatctatat caaatttctc
     2821 attagcacga tttgccttta gcatagaatg agtatttata atttcacttg ctttattata
     2881 aagctctttt gcttgtttat caaaataatt ttccatacat tatcccctta ttaaactata
     2941 agattcaaaa tatgatttta caaactcttc attttctata gcttttttat atacttcaat
     3001 ataactgttt ctaatatcct tcataatacc tatcattaaa tctacaggat acatttttaa
     3061 aaattcaata aatctattaa tatagtggtt tgattcatat ttatcattct taatatttaa
     3121 ttctaagtct tttagaatgt tcatagctga tagataaagt cttgtatgac tctcattttt
     3181 tactctttct acaatagact catcaataga ttctcctaaa aaaacatctt cataggatat
     3241 taatggttca gagtttgatt caataaaact tataaattct tctgcaataa ctttacctac
     3301 attacccttt acaacattta aaaatactgc tctaggaata gaattatttt tttctttata
     3361 aactttataa attttagata ctctctcata acttctagga gtggctctta catcatcttc
     3421 atttatttta tgcagatatt ctggaaaagt ggaaataaac tcgataactt ttctttcaat
     3481 accctcatct attgcccatt ttatccattg tgtatggtca ctctccatat ttaaccaaac
     3541 aaacctattt tcttgggctg catccatatc taccacttga taatcaaaat ctgaaccata
     3601 tttacttgat ggattcattg ctgctaaaat ctttacatca tcatgcagtt tatatccatt
     3661 aatttctcta tttaaaatta aattcataag ttcttgctgt actgtatgct cacaacgatt
     3721 tatctcatct ataaataaaa gaactgtctt acttttagat atctcttcat caatttctct
     3781 taatttgtta tgaacagcat acactgttgt tttcttttca gtcttatatc cattagaatt
     3841 aactcctaca taagattcta tagttggaag accacctatt tcaccctctt taagtaagtt
     3901 tccatcaata acaattaaac tccaatcatt ttctttggca agcttatttg ctaaagctgt
     3961 ttttcctatt ccactttcac ctactattaa aggtacttct ccagtggata atattaagtc
     4021 aacgcttttt aatgtgtcta taaaattcat ttttctctct cctacataat ctttaatttc
     4081 tcatctacag ctattttttt tgctgtctta cttccatatt tataaataaa cataatttta
     4141 tctattggta tactttcgct atttctatct ataacactac aattcaaaaa atctctaata
     4201 tacttttcct caacatcttc tttggataat acttctttta atacactctc taattcatct
     4261 ttagatactt ttttcagaat gtacttaatc actaaaatat tcacttttaa aaattccaac
     4321 attttatttt tatctaaatc agttataaag ctaatagctg cttcattatt ttttatagct
     4381 ataagttctg cattataact aggtgaatct atatatctca aggcatcata acttattctc
     4441 actgcctcct cttgtacact ttcataaggt tgttttataa actttatcga atcataattt
     4501 tttcttactg ctaacagttg taattcttca cttggatttt tagcatattt aattgcccat
     4561 cctgcttgat ttatagccat ttcaataact ttatcagttg ggtttttgat ataatccagt
     4621 atactccatc cctcatttac tgcttttatc atcatatctt ctgttggatt atctataaat
     4681 ttaattgctc taatattatt atctattgct agttcttgca tctctctggt tggattattt
     4741 atatattcta gtacaagccc attttcttta atagctaaca atttcatttc atcagttgga
     4801 ttatctattg tagctataat attgggatta ttttttatca tttcaataac tctcaatttt
     4861 tccataatgt gcctttcctt ctataattat ttttatatct atattaatta taataatcta
     4921 ttcctattta tataattgtt tcttattata attaatatac tttttaatca aatttaaaca
     4981 gaataattat accaatatat aaaaaaattt ctaaaaaaca ataaaattaa gttataaaca
     5041 ccaatatatt tctattattt caataagtat acaattagat tagaatctaa cgctagtaat
     5101 aaaaaattac tttcccaaaa tagatataag cctcatttta tcgttcaaat aatgaaaata
     5161 tatttgattt catgcaaaaa gagtgcctaa tgaactaaaa agttcatttt gagacactca
     5221 tttttttata taaatttata tagtttttaa tcgttcgcat tcaaccactc agttaagact
     5281 tttatatatt tctcattttc ttcaacgaat ggcatatgtc ttgaatactc aaataattcc
     5341 cacttactat taggtattct atcatacata gtctttgcaa tatatggtga acataaatct
     5401 attgctccac tagttactag acaaggctct tttatttcat gtaatctatc tgtaaattca
     5461 tatccagaaa gagttcctgt aggagaaaat tcattttgtc cccatcctac aatatatgct
     5521 tcagaacctg attttttagg tcttctcagg cactctggag aatcttctgt cacttcacct
     5581 gcacaataca tttccataaa tctttctaat gcatcattat attctttgct agagtaatct
     5641 ccagtattta ctgcatcaag taatgctttt tggtcaacct cactcatata tgatattctt
     5701 cttttttgtt ctttctccca aagttttgca gaagaaagag tagatgaaag gatgtaagac
     5761 ttaatacctt ttggtttata ttcaatagca taccaaatag cctgcatacc tccccaagat
     5821 tgacctaaca gatgaatttc atcaagtcct agatgttttc ttagttcaat aagctcctct
     5881 atccaagtat ctgcattaaa tagctcagga tgcccttcta caaatgaatt tccacaacca
     5941 atttggtcat acattattac ttgtctacca ctttcagcta tcttatccaa tacctcaaaa
     6001 tagttgtgtg tagaacctgg acctccatga agtaatacta atggcttctt cccttccgta
     6061 ttttctccta ctatacggta atacgtttta aaacctttaa aaggcatata tccttcagta
     6121 attttcatgt ttatctcctc caatttgtaa ttataaacaa taatcaagtt cattaacaat
     6181 actatttaaa acctcttata catatttgat tatgtatttt aatctttata cctactttta
     6241 taaatagtat aacataaaag ttaaaaatct ctatactaaa ccaattataa aattatatta
     6301 actatataat tttatttttt aataatagta tatacatatt tgattatttt catttgctat
     6361 ttaaaatcaa ttttaagttt tcttcttata ataaacttcc tctttgtggt ctcatgttag
     6421 tctctaaatt taaaatttta caaaaaattt tcataaaata aaattatatt gattgtatct
     6481 aaacaaatag ggcaataaaa taattaagta tagttactta cctttcaagc aatattagtt
     6541 ttatgttaga attttattat attgatttac aggaggtttg catttgaata atattaattc
     6601 acttaaagta ataaaattat ctcttggatg ttctcttgct atatttattg cttggctatt
     6661 aaaattagaa tactcaatgg ttgctggagt tatagtacta cttacagtaa aggacactaa
     6721 aagagaaact cttaaaggct ccattggaaa gatttatggt tttcttttat gtactatttt
     6781 ttcatattta tgttttaata ttttaggata taatttgact tcattttcaa tatttatatt
     6841 tataattata ccactttgtt ttttgttaaa tattcaagat gttattgcta tgtgtgtagt
     6901 catagcatcc cattactacc ttcaaggaga aacttctatc aaatggattt taaatgaagc
     6961 tggaatattt gcagtaggaa ctggaatagg tgtcttaata aatatgtata ttccaacaaa
     7021 tatacataaa atccatgaag ttcaaaaaaa gttacaggaa gaagtgagta ttgtacttat
     7081 agacattgca gatattattg taaatcctaa aaaagaaaat ggatatagta gagatttata
     7141 tacattaaat tcacttattg acagcagtat ttctgaaact tacgataata ttaataatac
     7201 tttattaagt gatactagat tcttcttaga gcatatggat attataaaaa gccaacggga
     7261 tatcttagaa aatttgtata gttatgtatc tcaactaaat tctacaccac cacaagctca
     7321 tattctatct gcttttatac ataagatagg ttatactgaa tttgaagctg aaacaggcaa
     7381 tcttcttctt gaagaattaa agagactaat gattagtatg aaaaaccagc ctctacctgt
     7441 tgacagaaca gagtttgaaa atagagctat tttattccta tgcttgactg agttaaaaca
     7501 gtttttagtt aatcgtaaac atgctcagat gcttagagat aataattttt ataaataaaa
     7561 aggggagaaa tctagcagtt gacctgacta caaaatatca gatataatat taaatgcgcc
     7621 cctagtaaga gggcgcaatg tttataactt attctactgt catgattaaa tcattattca
     7681 tatcgaacat acattatttg accaagtcca atattagctt tttcatcagt gatttctatt
     7741 ttaatagtca catcattttt tttacagtac ttcgctaatt ctgcaccaga acgattttta
     7801 ccactaaaat ctaaagaaaa tggcttatca tatttaaaag gatattcaac aggtttaccc
     7861 tctggtgcta atgcaaacat cccatatggt gtgttcataa atcctattac agcaatcgta
     7921 agatttgatg ggtctaaatt tgattcacta cctgtaaatg taattgtatt tactgatgaa
     7981 ttaactacac tacatctaac accttcatac attacatgtt tttcatttat atcttctcct
     8041 ttttttccaa aatttgcaac agcctttgcc ccttcttgat gtggtaacat agtgtgcttc
     8101 ccaggtggtg ctggtttctg tgtctgttct ggttttaccg tctgtactat tgcaccaact
     8161 tttggatatg ctgtcttatc aaatggtaat gggtggctaa gactcttgta tatgatatcc
     8221 tttcctgctg atttattagc atcaatatct acatgataca aacgcccatc accaaaacgg
     8281 ataagattcc actggtggtc atttgatgtg ctgtgtacat aataagattc aattcccata
     8341 gcatcacaca aagctttcat gctcctagcc attcctgagc atgcaccttt tttagtaacc
     8401 aatgtatagg cagtatttgc tccctctact gcattccagt caacatatgt tgtgttattt
     8461 ttaatgtgat tgtaggcaac taaaatctta gcatctgtgg tcatattctt tgtgattttc
     8521 ttgttcataa aatctgctgt tgcttgtgct actgagttta gttgggcttg tgacagcttt
     8581 ggaccatata cgctattggt tccagtgaca tagctttttg gtgtttttgc tgttacctct
     8641 ttggctgtca taccataaac tgtcatactc atacctgaga ttaaaactat tgttgtaatc
     8701 aataacttgg tagctaactt cctaattttc ttcatactta atattctcct ttataaaaca
     8761 ttgttacttc ctattctcta ccattaataa aattaattta ggatttaaaa aggtggattg
     8821 tcaacatgta tatttctcca ttcatacatt cgtgaaatat ttaaatttca tggaaaatct
     8881 aatagatatt ttctagataa tttgtataca atacaactcg caaatcaggg tgtttgctgt
     8941 tagtttgaga aaatgatgat gattaataca ttcggaatct ttgacctata ataaatacca
     9001 ttgtcttcaa tcattaataa tggtaagagt aaagagaatt atcaataata cagttaaaat
     9061 caactttgta tacatttcat acattctctc ccaacaacat tatacttctt ataatttgta
     9121 tattcaatac gttttctggg aaaatataga tatatctata aaaatataaa aaaggagttg
     9181 aacttaaaat ttgattaaaa aaaatcaatt ttaagacaac tcatttgtat tataaaaatg
     9241 ctatatatta ttattaagta agtcaatatt ttagatattt atctatttct tattgactta
     9301 cgcttatagt ctaacttatt tgtttagttg atatataacc tagttttaag cattattaat
     9361 atttaaataa tcaagtatcc tttttgtttc ttgtagtttc tgttctgcct catttaagtt
     9421 ttcttgaatt atagaaatat atattatatc tatcaacgta agcattgcta ttcttgaaga
     9481 aatagctcct tctctaagtc ttttttctat atttggtact actagcttta aatcactaat
     9541 cttactaaga tgattgtcac tatatttagt tatacaaatg accttacatc cttttaattt
     9601 tgcattttct atagacttta ttacttcttt tgattctcca gagtaagata ttgctatagc
     9661 tatatcttct ttatctacat ttgaagatac cataagttgt gtatgactat ctaaagaggt
     9721 aaatgcctgt ttatttatcc ttaaaagttt catctgtaaa tctagtgcaa ctaaagccga
     9781 accacctact ccaaatatat atacattttt agcctttatt atctgttcaa ctgcttcttt
     9841 tattatatct ttttcattca acaaccttgt ttggttgata gtctctatgt ttttgtttgt
     9901 aattttgttt ataacactat ctatattaca atcatagttt tcatctacat atgtgtattc
     9961 attttctttg cccatcaaat ctttagctat ctcaattttt aaatccccaa aacccgaata
    10021 tcccattttt ctagaaaacc taactatact tgctgtactt gtttttgagt ttgacgccaa
    10081 ttctgataca gaaagcttac ttatagcctc tgtattatta agtatgtaat cagctatttt
    10141 tttatctact tccgttaaat cttcatatat ctgttttaat tttaaaatgc aactcatact
    10201 ctaccacctc tacctattta ctataatatt tcttcttagc aagtaaacat gctcctaaat
    10261 ctggagtcaa cactggtctc actataccaa atctcgtttt attcaaatat tttttaagtg
    10321 gctctaatat taaatctcct gacttaaaca ctccacctga ataagatacc tttatctttg
    10381 taccttgttc aaaatgatgc tctaatccta ttataagcct acttaattca taagctgcat
    10441 catcaaatat tttactagca gtattatcac cttcaataac tgcttttaaa catatcgtag
    10501 caaactttgc tatttctatt ctatctcctt gtatttcatc atttacatat tttattatgt
    10561 cataatcatt ctctatatta agatgtcttt ttattaaatc atataatttt gtttttgaac
    10621 accttccatc agactgcatt gtgaacattt ttaaggtagc cattcctata taatacgctg
    10681 aaccttcatc tcctaataca tagccccatc ctccacatct gtgaagattc ccatctttat
    10741 ctaaagcctg tgctattgaa ccagtacctg caattatatt tatacctttt tccccattta
    10801 aagaacctgc taatgctatt tctacatcat tacctagagt ataatttata tgactatatg
    10861 cattttttgt tgctacttct aatgcataca atacttcttt tatttttcca tatccagcaa
    10921 gtccaacaaa tgcatacgtt atttcttcta catttatctt agcatcttta caaacttctt
    10981 ccaacccagt tattaataat ttcgttagat tatcaaatcc tatttgatta taatgacagg
    11041 ttcctttggt tatggttcct actatattta attcttcatc tactaatgta aatgttgttt
    11101 tcgttcctcc accatctaca cctaaaaaat acatactatc ctcctacaat atctttaata
    11161 attctttcaa tacttaatat ctaaaaataa ccttccaatg ctgttttttt aatattgaaa
    11221 ggttatcagt actattattt attttacaat ttttctattg attttaaagc ttcacttata
    11281 taaccttctt gtctatctag gatactcttt gcactatcct tatctaaacc actttttatc
    11341 ataaatatag ccaatttaac gctattatct gcttcttcta agaatttttc tgcaacatca
    11401 tattttacat ttgtagctat cattattatt ctttttgctc tttcaaccaa cttttcattt
    11461 gatgtcttaa catctaccat caagtttgag tatacttttc ccatcttaac catagaagct
    11521 gttgttaaca tattacatac cattttttga gctgtaccac ttttcattct agttgagccc
    11581 attattactt ctgcccctac tataatgttt attggtaaat ccgctttttt actcatttca
    11641 ctattcggat tcatagttat tgatagtact gcacacccca attccttagc atactccatt
    11701 gcacctataa cataaggagt ccttcctgat gcagctatac cacatataac atccttagat
    11761 gtaactcctc tatctattat atcttgcttt ccaagttctt tatcatcttc agcaccttct
    11821 attgctttaa atattgcttg atttccacca gctattatag cttgaacaag ctcaaaatcc
    11881 actccgtaag ttggaggaca ttctgtggca tctagtattc ctatcctacc actggtacct
    11941 gctcctatat agaataatct acctccctgt ttcattctat ctactattat attaacagct
    12001 tttgctatac tctccttttg ttcttcaaca gcataggcta cagttttatc ttcgttattt
    12061 attaattcta ttatgcctaa tgtatcttct ttatctattt gcaatgtatt cttatttcta
    12121 ccttctgtaa ctaaattttc taaagttttt attaacatat catttcctca ttttcttaat
    12181 attaaatttt taaacacatt ttaattccaa ctttcataat tatattttta taataaatta
    12241 atattttcat aataaattat tttgttgagg gtttaaaatt aaacttttgc catggtttaa
    12301 tataatctaa tataaataat tcttcttttc ttatatatcc tactacattc gatttaccac
    12361 tgtttttcat atcagtcaag gctatttgta actcccctgc ataatgacca tattcactac
    12421 tttcaattac tatatctcct ctttttatta ttttaggagt attaaatagt tcaaatttgt
    12481 atcctttata tttaacacga gattgagtag accttatcag actgtcagat atgtcccctc
    12541 tattaaaatg tatttcttca aagagtatct tcttctcaac ttctcgtata ttttcctcta
    12601 ttgctacatc aaatgtaacc atatcttttc tcatagaacc taataccttt agctcctcat
    12661 atgttggata acaatttgat attattatat catttatatt attcatagct attatatgct
    12721 ttacttgaat atctataggt agatttctgt gcatctcaat tgttggaagc ccatcagtta
    12781 caggccatgg tccaaatgta gtttcatttt gacttgttac aaaaactgct gttcttaatc
    12841 catacttatt aaatctttct gtacatttta taaagtgttc taaatttaat ccactatatc
    12901 tatgtggata aaagttatga catcctatca aattttcttt atttggttgg tagtccatta
    12961 ttgtatctat ataattagta ttattactca tattgatttc tattttaaga ttttgaggat
    13021 taaaagtcat taatgcctct tcagaacctg taaatcccat atcaagcctt attccgtctg
    13081 ccttcgtctt tttaaaaaaa ttcaaatctt tgtagcttat ttctaattca ccaaatactc
    13141 tgggatttac atcaagtatt acctcaaaac ctttaaactt agcgtattca tttatacttt
    13201 taaatttttt aattatattt tctttagtat ctttaactga taataaacat gaaaatatac
    13261 gtgtaaatcc attttcagca gctttatcta tataatcata tatttcctta gatgttgttt
    13321 tttctggata aattgatatt cctaatcttc ccatctgtgt catctcctta tatcctatat
    13381 gtgtttaaat ttatttcgaa ttacacgaaa cttttttaaa aatttgatga aaaaaagttt
    13441 catatatatt tataaaaaaa gaaaagttta ccttttcttt ttttataaac aatcaacaaa
    13501 atatcttcgt tacttatttc ataactgtta tactttgaaa tttatactaa tctaatatag
    13561 tttttaattt ccaatatagt ttctaattaa taagcttctt gctcttcaac tttttcttca
    13621 tgaagcaacc tcttatcgta catcttgaca aatggatagt aaattattat tgatatagct
    13681 atacataata agttaagaac tgaagctctc caatctccac cagtggctaa atatgcccct
    13741 actggtcctg gtaatgtcca aggagcagta actactactc tggatactaa attagcactc
    13801 atagcaaacc atgaaactgt tgccattact attggtgcca caacaaatgg tattattaat
    13861 attgggttta atactattgg tgctccaaat attattggtt catttatatt gaatattgct
    13921 ggtattacag ttgcttttcc taaagacttt ccataagctg attttgctct aaatgcaaga
    13981 agtaaagcta agcctattgt agctccagaa cctccaatcc atataaacca ttgaaaaaag
    14041 ggttcagcag caatacctgg aactgcttga cccgcagcat atgaagctgt attagcatct
    14101 aataattgta tccataaagg tcttgccaat gaacctatta ttgatacacc atgtattcca
    14161 aatgaccaaa aaaacgttat taaaaatatt agtataatta ctgatggtaa tgtgtcagtg
    14221 gctgaaacta atggagttac taatttagct atgaagccat gccaatcaaa ccctaggaaa
    14281 taagtaacaa tagccattaa aattattatt aatgcggctg gtgtcagagc ttcaaaagac
    14341 cttgtgactg atgctggaac tgcttctggc atggttatct tgaatttaga tttgtcagta
    14401 aatctataaa tctcaacacc tattatagat gttacaatag caacaaacat tgaacctcca
    14461 ccaagattag ccattggcat ttgccatcct tgaggaattg aattatacca agctaaaagt
    14521 tctggactct tttcaactat ctttaataaa tcaggggtaa gaccctctat tgcagtagga
    14581 actattgtca aaaggaatgt agctgtagct aataaacctc ctgtcaatcc atctaactta
    14641 tatgactttg ccaaactata acctatgcca aatgtagaat atactgatat aataaaaaat
    14701 gtcattctat atggtagtaa tattgtaact gcattttcct ttagatactg agttaccccc
    14761 catgaatctg gtaatggagg aaatgctaat atcaagaaaa atgacccaac tattataagt
    14821 ggtaatgaag ctacgattcc atctcttaca gctcttaagt gacgttgttc tgccaatctg
    14881 gccatagaag ttgataattt agtgtctaaa aattctgtaa atttatctag catcttttct
    14941 ctccttaatt aatatttatt tttattatca ttaaaatttt tataaaatca actttcttct
    15001 aatctaacaa cactgcaact actatttact caacagttct tgaacttgtt ttaataactt
    15061 tggtcctcct aatggactat aagcttgtgc ttgtattaat gcacatggta cactaacctc
    15121 atcagcaaaa gcttttaaat agtcaaatct atgtctgact tgtggagcta ccatagcaat
    15181 atcccatcca tttttaactt cattctcaaa ctcttgagta ccaacagcca aaacatctat
    15241 atctattcca ttttttgctc cttctttttg taatgcatta actgctatag cacttgacat
    15301 ccctgatgaa caaacaaata atactctcat attgattccc cctgtttttt tatttctttt
    15361 caatcattat agcatgtatt tttgattaca ggaatacgtt tgtatatatt ttttcatatt
    15421 ttacatttta aattgtaatt ttatttcatg tatttatatc ttgctttaat tgctttattt
    15481 atctaatcat tcttttgtct aaaattacac actacttaaa atactcatat cttttcttaa
    15541 aaaagaaaaa agactatctt attattaaca taaaatagtc tcaatacttt tttaaatatg
    15601 tattccttta tatatccaga agtaacctat tattgcaaat gataaagcaa ataaaatata
    15661 cagtctaaaa aatcccaaag aaaaacctct cttagtttca acaaagtatc ttgtatatgc
    15721 aactgcaaaa gatgtaatta atgaatttcc tataacaact ccaaatctat tatctattcc
    15781 aaatatagat aataacaaag gaaaaactac agtacttact agagatgaaa ctattaatat
    15841 taatccactt ttaaaactta tagttggaat attataatct gttctttgat ttttctccat
    15901 ttgtttctta gtatttttat tactttttgt actttttgca tttttataat tattattttt
    15961 ctttcttttc ttttttttat tattagacat gtcatttacc tccaaaaggt ttaggtgtta
    16021 tattccctaa aataacttta tttttagccc ctgttgcaga tattacatta gaaaaagaat
    16081 tatttaatgt ttcattgccc aagattacaa atgccaaagc ctcctttgca tcagaagaat
    16141 acccatattc atcttgagtt aatacttcaa cctctaataa taactctttt atatatccta
    16201 ttaaagttag attatgagct cctccacctc caattaataa agtatctaca ttaacctttg
    16261 gaagtatgaa gtttttataa ttataatata tagcttttgc cgtaaacata gttactgttg
    16321 ctatcaaatc atatttatct acatgtttat atttgttaag catgttatcc aaataaactt
    16381 gtccaaatac ctctcttcca gtgcttttag gtggcgcttg actaagatac ttatgactca
    16441 tcaaatcttt taacatttct tcattaattt taccttttga tgcaaagtat ccatttttat
    16501 catactttct attaaataat ctttgacata ctccatctat tatcatattt cctggtcctg
    16561 tatcaaatgc aaatacatca tctatgttac atgatttagg tattatagta atatttccta
    16621 ttccaccaat attttgaagt gctaaatttt tattgttatc actatataat aaaaattcac
    16681 tatatggtac taatggagca ccttctccac ctgctgctat atccattact ctaaaattag
    16741 atattacctt tgtatttgtt tcatatgcta taactgctgg ttcacctatt tgaagcgttg
    16801 aagatacaaa attattataa cttcttggta tatgaaagat tgtttgacca tgagatgcga
    16861 taaaatccaa atttgctata tgaaagtttg ctttatgaca cactgatttt acagctttac
    16921 taaataaata tccaagctta aaatttaagc tacagattaa atcaacactc gattcctctt
    16981 ctatacagca ctttcttatt tcgtctttta tatctttagg aatttctaga gttataaatt
    17041 ctatttgctt aactttagta tttctaccat tcccactaat ttcagctagt actgcatcaa
    17101 ctccatctaa ggaagttcct gacattaaac ctacactata catagttatc atccttttaa
    17161 gtttatagtt attcctcccc aaatcaaggt attaagttta ataattttag aattaatctt
    17221 atttcatctt taattacgat aatttactct tatgaaatta attgagttaa tcttatacac
    17281 gttttttacc ttagctaaat cttacattaa tttattttca gtgtcaatgt aatactatgt
    17341 aatttttttt cacaaacaaa acatattctc tctccaaaaa ccatattaaa atagttacta
    17401 caaataaaaa acataccagg tacatatctg atatgttttt catatataat aattattatt
    17461 ttataatata gatagaacat catttaaggc actaattaaa tcttcactat tttcaagaac
    17521 taaatttatt cttattgtat atgtcgattt gtatatgatg atagatttta tagtctaata
    17581 acctaactat ctaggcttaa ataatctgat atatcataaa aatagatatt aaaaattgta
    17641 tatgaaccat tttccgaaca tacctcaatc tcatgcccta aactatctat cattttcttt
    17701 acaaaataca tccccattcc agtagactta tacaattgat ttcttccatt tttccccgta
    17761 aatcccttgt caaaaaccct agatatatct tcctcattta tacctatacc aaaatctttt
    17821 atagataata ccactccatt ttctaacttt tttgaattaa attcaatctt accaacttcc
    17881 tttgaatact ttatagcatt attaataatt tggtctaaaa catatgacat gcatttagaa
    17941 tctgtgtaaa catcattttc taattcattc aaactaactt ctacattatt ttttataagc
    18001 aaaaatgaat tattttttat agacattttt accaattttt ctaaattaaa tttatttata
    18061 aatacatctt caaacatagt gttgcttcta ctactataca aaatagagtt tactaaaaaa
    18121 tttatctttg caacctgatt cttaatatcc aaactatctt ctatgctact taacctatct
    18181 gtaattatac ttaaagaaga tattggaatt tttatttcat gaacccattt agctatgtac
    18241 tcatccaatt cttttaatga ttgtttataa gtctctatgt cactattatt ttttattttt
    18301 aagttttcta taatatcttt tattagattt tcttcaaaag attgtccatc aactaaataa
    18361 ctgtctattt caccactatt ttctatacaa ttatataaat ttgtgtaact atttctaaaa
    18421 tttatataat ctataacaaa aaataccatt attataaaca gcactaaaaa atctaaatat
    18481 attaactctg aatatttatt tttaaaaata tctatagcaa ataagtagat atttattata
    18541 ctaactacaa ctaaaggtag agcaatatac ttagacctac ctttcaaata ttttactagc
    18601 attgtattat atatcctatc cccttcttag tttttataaa atcatcaaaa cctagttctt
    18661 taactttact tctcaatcta ttcatattta cagtaagtgc attgtctgtc acaaactcat
    18721 cattatccca tagagtcatc ataagacttt cccttgatac aaccctattc ttatttttta
    18781 ataataatgt taaaattttt atttcgtttt tagtcaactc tatactttta tccttatact
    18841 tatgttttat aatccctttc cccacatcaa acatcaaatc ttcacaatac aaaatactat
    18901 tagaatcact ataattatag actcttctta ttataccatt tattttggta accaatattt
    18961 ctatagaaaa tggtttggta atgtaatcat ctgctccatt atttataccc attattaaat
    19021 ccatatcaga atctcttgat gataaaaata ttaatggtac atttgaaata gctcttattt
    19081 tttcgcacca gtaaaatcca ttatataatg gtaaatttac atctaaaagt actacatctg
    19141 gttttttatc tataaattca tctaatacta cctcaaaatc atcaattaat tctactttaa
    19201 atccccattt ttcaagtgct aatgcaatct cttttgataa atcaatatcg tcctctacta
    19261 ataaaattct atacatttgt atattctcca ttatcctaat atttcactat gctatgaatt
    19321 attaatatca taacatattt tatatgaatt tattacccaa attatttagt taatcaacaa
    19381 ggagactctt attacaagaa tctcctttct ctttattaat atatcaacta atttttatac
    19441 actacactct taaacttatt aacagatact gctccatata ttatgaatat tatcaaacat
    19501 atcactaaac ttagtatata tataccaaat aaatcggtca tcaataaatc tcctgctaat
    19561 ctcaatgcaa aataactaga tatagttgca cttaacattg gcaaagtata aaaaatagct
    19621 acttctttaa gtatagctct atttatatct ttttctgtag tacctatttt taacaaaatc
    19681 ttatatttct ctttatcttc atatgcatca ctatatattt tcatatatat tatacttcca
    19741 gctacaattg caaagactaa gaataaaaac acactacata tgcaaacttc atccattgac
    19801 tctcaccttg agctttatat ccattttgaa tatacacatt ttttaaactt aaattctttt
    19861 caatattgtt gaacattact tgactatttt cttcttgaaa tacctttgca ccataaaaat
    19921 acacttgttg acccttatct cttagtttaa aatatgtatc atcatttacc actataatac
    19981 tttgattaag tcctgtccct agtactggaa cttttacttc tccccttgaa atattatata
    20041 actgaccatc aagttttatc ttggcttctt ttgtagctat tgatgctatc gtttgagggc
    20101 tttttaactc tattacatta tttccactaa ctaatctttc accatactct tttaattctt
    20161 tatcattgcc attcacttta agagtattac aaaaatcact atatttcatt atagtatctg
    20221 ttgtatcata agcttctttt atatctgttt tctttaaaat tgttagttct ggatttactg
    20281 agtactttat cttattagta tcttttatta tattctctat ttgtttttta ttcacttcat
    20341 ctttatccat tgaaactatg ctaatagtgt acacatttct ttgttcttgg gcattcttat
    20401 gtatacgctt catcgcaact gaagcaccaa gagttgatat tgttgtagtt ataattatag
    20461 ctattatagc ataagtttta tagtttttat ttaatcggta gtttatattg tttattgcaa
    20521 ttatattatt tccattaaat aatatttttt tatttttgat tataatatca aatataacag
    20581 gcataactga tttgaataat ccataagtac ctactattat tatacctata acaggtagta
    20641 cactagttat atctccagtt cttatattgg tagaaagata gtagccatat cctattacta
    20701 taattgatac tatagctaat atatatatac ctattcctac ctttggtatt ttttcttgtt
    20761 ttttagatat attgattaga tttattacac tacttctaca tattgttata aaacctttta
    20821 cagccattat tataaatata gaaataaaga ttaaagtagc atatagtata gcttctatac
    20881 taagtccatt agataccttt atattaaatc cagataactt tattatcact acttgaaaaa
    20941 atctagatgt tattatccct ataattattc ctgttataca agaacttatt cctataagca
    21001 tattttctat aaaatatatt tttcctatag tatataaatc taatcccata aaagacaata
    21061 ttccaatttc tttagaccta ttcttaaaaa atatatttgt tgcataccat ataaagaaaa
    21121 ataaaaatac tgatagtatc attattacag ctactaacac tgatagtgta aattttttat
    21181 tttcatcttg taacacattt atagcatcac catatcttaa taattcaaaa ttagttagca
    21241 caactactga aaaaaccata gatataaaaa atgctagata agttcttatg ttactcttaa
    21301 aattattata agcaattcca agtatactca cttacatctc acctcccata gaggctagca
    21361 tatccataat ttttccataa aattcttttc tactatttcc tttgtttaat ttacacttta
    21421 tatttccatc atttatcata tatacttcat ttgaataact tgctgttaga gggtcatgtg
    21481 taatcattat aatagtagcg ttattttctc tgtttatttt ttctaatgat tctaaaagtt
    21541 catatgctga tttagagtct aaagcaccag ttggctcatc agcaaatatg actgttggat
    21601 ttgtaattaa tgacctagct gctgcgcctc tttgtttttg tcctcctgat aactgatatg
    21661 gatatttatc taaatgattt tctaatccaa attttttagc tatagaaaat accttagctt
    21721 ctatctcctt acttttcttt tttcctaatg ctagaggaag tgctatattg tccattagtt
    21781 tcatattgtc taatagatta tagtcttgaa atataaaccc tattttttct cttcttaatt
    21841 ttgatagttc attatttttt acttttgata tattaattcc atctagtatt atttctcctg
    21901 aagtttgttt gtcaagtgta gacattaaat ttagcaatgt tgtctttcct gcaccagatg
    21961 gacccattat tgatataaaa tcaccttcat tgactgtaag agatatattt tttaacacat
    22021 ttgttttaaa tccttttatt ccataatctt ttgatatatt ttttattttt aatatttctt
    22081 tcataataat agcctccagt tgctaatttt ttaatatata tttattttaa aggttttata
    22141 taaataaatc cttaagtaaa tattacattt taactgttag cattacactt ttgtaacata
    22201 tggaagacta ttataattat agtagaaata tcttaaaata aaaacttgct tcactttttt
    22261 gtataaacaa agaaaagaag ctcctaagaa gcctctaatc tatacaataa ttcttctcta
    22321 taaaaaacca aaatacacat tgattgtggc aaatacagat actataaaca agtgatatta
    22381 ctactatata ttaaaacaat tattcctgaa gataattcaa taagactatc aagcaataag
    22441 ctaagcatcc aaaaagactt aataccatta atgtataatt atacccaata ttaatgctca
    22501 aaaaaccagc aacagttgga ataatcagaa atgaacctcc cataaatata cttaaagcta
    22561 ttaattggct actacttcta agttttttag gagaaacttc aaatattaat ctttttgaag
    22621 taattaaaat taaaggagta gaaaacactt gaaaaacaca cagtataata atgatatttg
    22681 aatcatttgt taaagcaaat aatagaaact gaactgttat cataatagca cttaatttta
    22741 ataagtttaa actgctatat ttttttaata aataagaacc agccagatat gttggtatct
    22801 ctaacaatga ctgtaaagac cactttaaag atatctgaga atttgtagca tttaaagcta
    22861 tcattttatc tattacagta cagttatttg ctaccaccat tgagtataat aagaataaaa
    22921 tacatactag taagatatat tttttatctt ttaataattc aataatatct ttattagtta
    22981 catttatttt cttattaatc ttttcaatat caggtaataa tagtatattt ataataagta
    23041 atactacaat taaaccaatc gctacagata atccaaaata tgagaatcta agaatcaagt
    23101 aagatgctac catacttcca atagcccatc caatcgaccc aaaagtctta ataaatgaca
    23161 aataattatt aatattatct ccacaaccta ttatccatgt atcatataaa ctacagcaag
    23221 tatttaataa tcctcctgat aaagcaacaa gtaataagta tattataaaa gttgcagatt
    23281 cagtagaaaa cataataact gatgcaattc cataaactga taaactaatt aaaacaattt
    23341 ttttcattgt ttgatactta tcagctaata ctccaaataa taattgaaac aatatattgg
    23401 ttattgcata gctcgataat ataattcctc tttcaaacgc tgagtaacct aattttgata
    23461 agaaaggtgt gaattttgtt gaagcaaagg caaaaataat atatgagaaa aaatagaata
    23521 tgataaattt aaatttaatc gctttattaa tcataatcaa tcaaaattga taactttaat
    23581 accactattt ccttcctgat ttaagtttga aagatgatat tttaccgtat taggattctc
    23641 tacaataact aaaggaatat ataaagtatt ttcaagtaac ttattatcaa tttctactaa
    23701 cttttccccc atattaactt cttgaccttg tttaacttct aatttaaagt tttctttttt
    23761 tgttgttgca ctatccaatc caatatgaat aagaatttga acatcatttt gcaatttaat
    23821 tcctatagca tggttagttt gagcaataaa acttattact cctttagtcg gtgatttaag
    23881 aatattgtcc tttgctatca tagcaaatcc atctcccatt accttagttg aaaatacttt
    23941 atcaggaatt tctccaagat taattatttt tccatcaatg tatgaattaa ttgtaattgc
    24001 ttcttttttt cttttaaaga acattataga cactcctcta cataattaac tttattctaa
    24061 ttatcattac aaataacgat attaagcata ctgcaattga ggaaaaaaga gccttatagc
    24121 tctttcccca ttgtagttct ttaatactgc ttatgatttg tttaattcca acaaatttat
    24181 aaatataggt aaacatgata acaatagtta ttgtgtaaat ttggaatatc tgccctaata
    24241 agactaaata gaaagcaatc atgttttctt ttatctcttt attctttttt atattgtaaa
    24301 taacatatgc actgtatact gcactaaagt tagagattaa atttaaactt gcattaacat
    24361 cattgtttaa aagttgtgaa aatgaaatat ttgtaaataa tgatgtcaat tctaaataca
    24421 ctatatataa aacaggtaat attagaaaac aaaccataac cactgaaaga aatatatttt
    24481 catcttttaa tactgctgtg atatttttta ttttatttgt tatcatgttt ttgttctcct
    24541 tatttaaaag ttggccagaa atccttatta gccacaatca tttcatctaa gatttctttt
    24601 gctacttttg cacttggaac agttttactc atagtaaacg actgccataa tttttgataa
    24661 cttttttcta tccatgcttc tacagctaat ttttcagaag caacttgttg ttccattaaa
    24721 cctttttgga aagttggaat tttacctata gacataggtt caaccatatc ttttccaaca
    24781 aggcaaggaa tttcaaccat tgcatcatct gcaaaatttt caatagctcc attattagga
    24841 acaatcagta aaaatctttc ctgagtatta aatgctaatg cacaagctaa ttcaacaata
    24901 aattgagaat gctcacttgc atcaaaccat gtatcccttg ctgtgccatt ttttataatt
    24961 ctttcacatt cttcgaatgt atccttttct cttctatcca taatttcatt tgctcttgta
    25021 taatttggat tagcatgttc aacagtttca tcagccatta aataatattt taaataagta
    25081 ttaggtaatg tagtcggttc tatttccaat aaatcctttg ctgctctcat agtttctaac
    25141 caactagatt ctttgtgttg accttgaggt gtaaattcct catatccttt tttagcacaa
    25201 tattcttgta atttaggcat taaatcattt ccttctttgt ccttaatact tgtccaccac
    25261 ccgaaatgat tcaatccata atatctaaca tcaaagtctt tacgagaatt taaacctaaa
    25321 actctagcaa atatttcctc taaacatact ggcatatcac aaatattaat aattcttgaa
    25381 tttggtctta atacacgaca tgcttctgca actatagctg ctggatttga ataattaagc
    25441 atccaagcat ttggagaata tttttccata taatcaatca tttcgattat tggacctatt
    25501 gttcttaatc cataggcaat tccacctgcc ccacaagttt cttgaccaac aaccccatat
    25561 tttagtggaa ttttttcatc ttgttcacgt aaagcatata aaccaacacg aatttgtgcc
    25621 attacaaaat caatatcagt aaatgcttct tctggatttg ttgtataact aaatttaatt
    25681 tctggatttt tctctctaac aattattgca catgcttcag caacttttct ttgtctctca
    25741 tcattattat catataattt aattgattca ataggaaatt tagcaacact ttcaattaac
    25801 attgttacaa ttccagcagt ataagtacta cccccaccag caattagtat cctctgtctt
    25861 tttctttcca tctttccttc tcctttataa taaattttca aattcttctc ttacacttgg
    25921 tactgaaagc ccaataataa tctgaatagc ttttccatta tgcactaaac catgtgcacc
    25981 tactgcctta aaatcttctt ctttagaaat aattgagtca tctttcaagg ttaatctcaa
    26041 tctcgtagca cagtttgtaa catctacaac attttctgct ccaccaacta attttatgta
    26101 ttcatatgct tgttgagagg ctttactcaa tttatttcct ttttcatctt tcgtttctaa
    26161 atattcattt ttagtatata gttttgtttc ttcactatct tcttctctac caggagtttt
    26221 catatcaaac ttcttaatta agaaagtaaa tacaaagaac cagataaatg aaaatataat
    26281 ccctacaaca acttgaacaa catatacctt ccagtgatac attccaagag gaagccaatt
    26341 taatacaacc cagttaataa ttcctccacc aaaatcacca acaactccta aggcaaacga
    26401 aatcgtttgc aagcatgcat ctaaaaatgc atgtactagg aataaaagtg gtgctacaaa
    26461 taaaaatgta aattctaacg gctcagtaat tccagttaat actgcagtaa gagtagcagg
    26521 aatcattaaa cctaatactt ttttcttttt ttctggcttt gcagttacat agaaagcacc
    26581 aaatacacct aatgaaccaa acaccttcga taatccggat aatgaaaatc cgattggata
    26641 catttccttt agagtcttag ctgaagtttg aaaatcctga atatgagtag cccaatatac
    26701 tgatgtacca cctggaacaa caacactatc ataacaaatt ggtgcatata caaaatgatg
    26761 taatccagtt ggtattaaaa tcttttgtaa gaatgcataa caccaaactc ctatatttcc
    26821 actatttata aaaaacgttt gcaaatgtct aataacattt tgaatatgag gccaaataaa
    26881 acaagttaat aatgcaactg gtatcataac aaagaaacaa attgcaacta caagtgatga
    26941 gcctctaaat aatccaataa aatctggcag ttctttatca taaaatctat tatgaatata
    27001 aatgacaata cctgatatta acaaagcacc aaccatacca gtatctaatg ttttaatacc
    27061 agcaatgctt acaagtccac ttccagcact tatttcagct gcgaaatcaa ctccaaagct
    27121 ttttccccaa aaacttaaca tagaacctac aaaataatta aaagtcaaat acgttgctaa
    27181 agcctccata caagctcttg cttgttgctt ttttgcaagt gctattggta aagaaatagc
    27241 aaataataat ggcaattgat taaataccat ccaagctcca ctagatatta caccccaaaa
    27301 ttggtaccaa atattttctg gtgtagcagg tgaacccata attgactgat tttgaaatac
    27361 aattgagaat ccaaccatta tcccagcaaa agcaaataat agtgttggtg taaacattgc
    27421 ccctccaaaa cgctgtattt tcttcatcat ataaattact cccctcctca tatttttagt
    27481 ttatctttgg ccttagatat ctattatttt aacaggttaa taaatatata caatctttag
    27541 ggtacattcg gagcttattc acagtcaaat aagtttttgc acatttttat gttcaaattc
    27601 tcataaaaaa aaagaatgac tacaatttgc aatcaatccc ttctgtaatc attctatgcc
    27661 ttttataaat actatattta ataaataata actcaatcaa tataaaatat aacattgtca
    27721 atttataact agggtgcatt tgtaaaaatg agatattagt cgctgaaata taaattgatt
    27781 catcacttaa atcagtcaat gtattatttt taaactctgt aattgaaatt attttagttc
    27841 ctattaattt taatcttcta gcaatattaa gtgtattctc attctcacca cttagggata
    27901 taataatcat aacatcattt ttactgacaa tattgtaaaa agaatcatca aatgttcttc
    27961 cctcaaaatc atatattatt tcttgacatg ataagaacat tctctttatc tgttttgcaa
    28021 ccacattttg aatatcacct gaaccataag cgtatattgt tcttgattca taaagaagtt
    28081 tacacaatgc atcataatct ttattttttt gatcttcaac atacttaatt attgaattac
    28141 atgcaatatc aaatgactga ttttctatga catgaacctt ttctgattcc cagcttaata
    28201 atactttaaa ctcactgaaa ccttttaaat ctaatttttt aacaaatctt gtaatagttg
    28261 cacgagacac attacatttc atagcaagtt catttattga catcttacta caatgttttt
    28321 tatttgcagt tatatatttc catattaata aatctgtatc attcaattta ttataattta
    28381 aaaaaatcat ttcttctaat ctcataaact attaccccct ttaattaaaa atcgtcataa
    28441 atattatacc aatattcaac attaaattac agcgtattct tatatttact atttagccca
    28501 taaaattgac tataaaaaat actgctataa ttgatgttta aaaaaatgta gttttaattt
    28561 tattctttta tctaataatt aatattttca agttctagtg cttttcttat acaattatca
    28621 tctttaaaat cagcagtcct tttacaatct tttactttaa attctggaat agttttaaat
    28681 tcctcatcac atattccatt cttatttaaa tacatacaac ttgccattct aactattaga
    28741 ccactatttt ttaaattaaa caatacaggg tctatacacc ctccatctcc gccagtagtt
    28801 tcaccaacta aagtcgcaaa tttattttct ttacaaaaca ttgcaaatga ctctgatgat
    28861 gaatatattt ttctatcaac aagtaagtat atattaccct taaattttga atcatctgta
    28921 gattttatag tataggaagt atcttcaaaa tcattaaaat cttttataat ttctttaggt
    28981 gcattttcct ttacacttgc tggtaaattt tctacaggat ttaattttat atttcttgca
    29041 tttgtatatt tttttactat ttcattatta tttctataaa ttctataacc atttattttg
    29101 acatcatttt ttatgagttt agatacgatt ccctgccaat acctatcact tccacctaaa
    29161 ttacctctta tatcaataat taaagcttta tgtttttcta aagtgttaat ataatctcca
    29221 attattttta aatcattatt tatagagcca ttctttgatg acattgatgg taaatacata
    29281 tatccaatct gacccttaat aacatccttt aaaattaatt ctttttttac aaaaatatca
    29341 tctggcattt ttattttaag attcatagag tcatatctat ccacaacttt tttatcatta
    29401 agaaaatcat accaatcatt attagagtat gatttcttaa aaagttcata tcttttctta
    29461 ttatctatta cttctgtgtg tttattattt aaatcagata atatagatga cagttcttct
    29521 ataaattctt catcattttc agtgtttttt attcgttttg tatattcatc cttatttgct
    29581 aaccaatcaa tattattaag cctcttattt acacctagat atggatatcc tgtctttaca
    29641 acattataca cataattaaa gtcatccacc ttttcctctt cagacaactg attcttttga
    29701 gaataagtag aattacctaa taatattata aatgctaaaa taattactaa aaataatact
    29761 ttctttttca tgtaattctc atccactttc agattttata ttttaataca ttgtatcatt
    29821 attttattat cacctaaaca gttaaaagaa attcttgaag atatattcca ctattattct
    29881 atttaaaaat ttttatttgt attttcaaaa ttatttcatg aaagttataa aataacaatt
    29941 atattcaaat atctatttta ctgctatatc ctgaaagtaa attcttatca gtgatatact
    30001 aaaaaagata tgctaaaaaa tttatccatt ataatgactt aaatttagat actttactga
    30061 tttttattta ttagttgaga aagatattga taattaaaaa tattgataac tatagaaatg
    30121 attatttttt atagaaattt taaggatata aactaattat acttaagtct atatccttaa
    30181 tttatcatga ttatgagaat ttttacaaat acttatcttt gtccgtttta gaataaaaac
    30241 aagaacatat cctgttattt tattcaaaca tccaagttta attactacac aattacttat
    30301 tagaaattgt atctacttca tatatatatc tgttaagtat agcttctagc atttcttgtc
    30361 ttccagactt attctttata actggcattt gcagtgcata agattctaac tctttaaatc
    30421 caaccttacc ttctactata tccttaccta taccttcact aaaacttgca tatctttctt
    30481 tagtaaagtt ctcaaatacc tcatcttcta ataatttatg agctattaat aatccctttg
    30541 caaatgtatc cattcctgca atataagcta ggaataagtc ttctacctca aaagatgctc
    30601 ttcttacttt agagtcaaag ttaaatcctc ctggtgctat tccaccttgc tttaacactt
    30661 catacatagc aagtgttgca tcatatatat ttgttggaaa ttggtctgta tcccaaccta
    30721 ataataggtc tccttgattt gcatctatac tacctaaaac attgtttatt cttgctatat
    30781 ttaattcatg ttggaaagta tgtcctgcaa gtgttgcatg gtttgcttct atattcattt
    30841 tgaagtattt atccagatta tactttctta aaaatcctaa aacagtagca gtatcaaaat
    30901 cgtattgatg tttagtaggc tcttttggct taggctctat taagaattgt ccactgaatc
    30961 ctatttcctt agcataatct acagccattt gtaagaatct tgcaaagtta tccatttcaa
    31021 gttctgtatt agtgttaagt aaagtttcat aaccttctct tccaccccag aatacaaaat
    31081 tttctcctcc taagtactta gttatttcca tagctttttt aacctgagct gctgcatatg
    31141 catatacatc tgcattacat gttgtagatg caccatgaac aaatcttgga tttccaaaca
    31201 tattggcagt tccccataat aactttatac ctgtcttttc catattaact tttatatact
    31261 caactatttc atctaatatc ttatttgtct cttctaaatc tcttccttct ggtgctatat
    31321 ctctgtcatg aaaacagaaa tactcaattc ccatcttaga cataaattca aatcctgcat
    31381 caactttaat ctttgctatc tcaattgggt ctgttatatt attccaaggt ctctctactg
    31441 tccctactcc aaatgggtca ttaccctctc cacataaagt atgccaatag ctcattgcaa
    31501 atcttaagtg ttctttcata gtcttattac ctaccacttg ttcaggattg tagtatctaa
    31561 atgctaattc attgtcagat tttactcctt caaattttat ctgtcctatt cctttaaata
    31621 tttcactcat ttcatgtcct cctaatattt tacacatata atatatgtag tatgttttct
    31681 taatttaaaa ctattttcta tctttatttt tctttttaag ctaatttaat tatttatttt
    31741 tgcattaact acttcatcta ataacttaaa gtcatctttc aaagatttgt atattctttt
    31801 atacaatcta tgatatatat tgtatgtatc tacattttca cttattggtt ctaatttagt
    31861 tgaagttttt attatagcat cacaagcttt ttgtatattt tcatatattc cagctcctac
    31921 taatgcaaga attgcaactc caagtgctgg tccttcactt gaatttatag tatatacatc
    31981 ttgattaaac atatctgctt gcatctgtct ccatacttta ctttttccac ctccacctga
    32041 ggctcttact tcattaacgt ctatattaag attctctatt atatccatac agtctttaag
    32101 actatatgaa acaccttcca ttattgacct tgcgatttct tttttagaat ggattggaga
    32161 taatccaaag aacacacctc ttgcataagg gtcaagatga ggagttcttt ctcccatcat
    32221 atatggtaag taaagcaatc cattacatcc tgttggtact ttacttactt gattatttat
    32281 aatctcatat acatcttcac ctaaagaatt tgaaacttcc acttcacttt gacagaaatt
    32341 atctttaaac cattttaatg acaagccagc tccttgagta actcccataa catgccatgt
    32401 atttggtatt gcatgacaga aagtatgaac tctaccttct ttatcaattt ttggctcttt
    32461 tgtataagca aatactacac ctgatgtacc tatagtagat gaaactactc catctttaac
    32521 tattccattt cctatagctc ctgctgcttg gtctccagct cctcctacca ctattgttcc
    32581 ttctttaagc cctgtcaaac ttgctacatc tctagtcaca taacctgtaa tttcttgtga
    32641 ttcataaact ttacctaaaa gatttttatc tatatttaac ttttctagta cttcatcgct
    32701 ccaatctctt tttcttatat cgagcaactg cataccactt gcatctgata cctctgtagc
    32761 atattcacct gtcaatttgt atcttatata atcttttgga agaagtattt tattagtatt
    32821 tttatatata tctggttcat tgtttctaac ccataatatc tttgatgctg taaatcctgt
    32881 aagtgctgga ttagcagtta tttcaatcag tctttcttca cctactaaat cagttatctc
    32941 ctcacactct tttactgttc gttggtcaca ccatattata gagtttctca atgttttacc
    33001 ttcattgtcc agaataacta gaccatgcat ctgtcctgat aatccaattc cttttataca
    33061 ttcactgctt atatttgaac tttgaactac ttctcttata gattcgacta cagctttcca
    33121 ccaatcattt gcatcctgct ctgcccaacc tgatttctct tgtataagag gatattcata
    33181 tgtacaactt tttatagtat ttcctagttt atcaaataaa actgttttcg tacctgatgt
    33241 accaatatcc acacctaata catactccaa cttcatccct ccttgaatgc cacttcataa
    33301 ctatcgtttt cctatcctaa tttttttata ttttaggtat attttacttg ctttattttt
    33361 gttagtatat taaactaact tatgaactaa taataaaata tttaattatc tttgtcaatg
    33421 caaaataacc ttttattttt gtgtaaaaag tattacaata ttattttaag gaggaatatc
    33481 aaattggtta ctgataaata cactattcga gaaatgaatg aaagattggt acttgaacaa
    33541 attataaaaa atggtcctat ttctagggca agtatagctt ctaccatagg attgaataaa
    33601 gcaactatat ccgctattac caaaaaactt attgatgaat ctctagttca tgaaatcgga
    33661 attggaaata gtactcatag tggcggaaga aaacccatat tattagtatt taataaatgt
    33721 gcagggattt ctttaagtat ggacattgga tacgactata tattttcttc tctatcttac
    33781 ttagatggaa ctattataaa ttctaagaaa ttaacagata tacaagtaag taaagacaat
    33841 gttatacaat tgatagatga aattataaat agttataaca tatccaaaat agacactcct
    33901 tataaggtaa ttggtcttac tttggctata catgggatta cttgtgaaaa taaagtattg
    33961 tttactccat attacaatct taatgagatt gacttatata gcatccttag caaaaagtat
    34021 gactttccta ttcacataga aaatgaagca aacttaacag ctttagctga gaatactttt
    34081 tcaactgtac ataactcact acttagtctc agtattcaca gtggatttgg ttcaggcatt
    34141 ataataaata ataaattata tagtggcaga aatggtatga gtggagaaat tggtcacact
    34201 atcatcatgc ctaacggtaa actatgtcct tgtggaaatc gtggctgttt agaacagtat
    34261 tgttcagaaa aaaaggtatt tgaacagctt tcttctttag aaaatattcc taaaatagat
    34321 tctgatatag taaagcaact atattatgaa gataaccaga atgccaaaaa agttattcat
    34381 gagttttgta gttacttaac aatagctata aataatgcta ttacaactta tgctcctgaa
    34441 ataatatatt taaatagcca aataattagt gatatccctg agatattaca gattacaaaa
    34501 gatatgttag ttagctcttt taacaaagga ataaatatag aaatttcatc attagggtct
    34561 gaggcatctc tatatggtgg ctctgccgta aatatcaaga gctttttgaa tatacaaaat
    34621 ttaactttaa ttaatgaaat ataagggtta tgactatata cagccataac cctttaaatt
    34681 atacattcta aaattagatt tattatatag tttatgcaag attagctata ttttttaaaa
    34741 attgtatatc aattaaatat taacataagt atttcgtttt aaatattaat ataatcttcc
    34801 tactcatcat cagataataa acttgcattt tgttcaacca tagaaatatt atctttacct
    34861 attttctcta attttgctgc caattccttt gtatctaaaa aagctgattc aataaccata
    34921 cctaaattta gccctgaaat aattttaatt cgactgtcat tattggctac taataaagca
    34981 gcattgcatg gagttccacc tagtaaatct gccattataa ttatttctga actttccttg
    35041 tacacttcta aagctttttt taatttttct attgttcctt ctattccatc atcttgtttc
    35101 atgtttacag taggataatc tatagaatcc cctattatca tttttgcaga atttaagact
    35161 tcttcagcca tattgccatg actcatcaaa ataatactat tcaatttaat acacctcttt
    35221 aaatctataa gatgtctaca agataagttt tcttatcatc aggcgtcatt atagttgtaa
    35281 tttcaattcc ttcatctaaa agtcttttaa atgcttcttt ctcttcttca gtaacactga
    35341 tattaggtct tagaactgtt gtatcttttc tacttgacat atttcctaca tttatattat
    35401 gtattttaaa tcctgcctct acaaatggaa taaggtccac aggagactta acaattaata
    35461 atacattttg tccttcatac tttcctgcag taatattttt tatagcagtc tcttctgtaa
    35521 ttatagatga cgctatacct gcaggtgtag ccattcttaa aacttgtttt tgaacagaat
    35581 tgttagctac tgcatcattt actaccatta atcttgtaac acccaattta ttactccaca
    35641 tagttgcaac ttgaccatgg attaaacggt catctatacg aatattttta atacctttca
    35701 tttccatatc taatatcatc ctttccttat tttaaaatac ctaatgcata taaaattatt
    35761 gaaacaacca ttactcctaa aattaagtat ataggtttta tattcttttt aagagcccaa
    35821 taaacaatca caactaaaat tgcaggaact aacccaggca taatttggtc taatatttct
    35881 tgacctttca ttgtaaaatc accttgttga aagttcaaag caacattagc ttttacaact
    35941 gaaggtatta atgcacctac aaccattaaa cctaaaatag atgtactctc agttaaaatc
    36001 tttaaacttt tttcaattga agatattagc ttagtacctg atgtataacc agcattaaat
    36061 agtggtatac ttaataattt caatgctaca ctcactacaa tccacagtaa gattccaaat
    36121 ggacttccat ctatcgccat attagctgct atagctccaa aaattgtcca cggaataacg
    36181 acaaataaac tatctcctaa acctgctact ggtcccatca agcctgtttt aattgaagca
    36241 acagcctctt cagtctcttc acttgataac tcctccattg ctacattaat acccaaaata
    36301 taaggggcaa cccaaggatt agtgttaaaa aattgtaaat gatttaatac agcactttgt
    36361 aacttttctg gattatcttt gtatactact tttaaaaaag gtagtactgc ataacagtat
    36421 gccaaggcct gcatcttctc ataatttgaa gaaacagaac tagtaaaaaa ccagcgccat
    36481 aagacacttt ttttcacctt ttcatttgat ttatttaatg ataccttatc actcatcttc
    36541 gtccatacct cctactacag tatattgttg ttcttgattt tccaaattct ttttgtaaat
    36601 tataagtgca attgctccac caattaaagc tacacctaat aatggtactt tcatatatac
    36661 tgctaaaaca aaaccaatta ctaagtaact aaaatactcc ttagcaggaa gatatctaag
    36721 taataatcct atccctactg ctggaagtag tcctccagct actgttaaac cacctgttaa
    36781 ccattcaggt gtatatttca aaatggtatt aattaaagaa ggtccaaata ttacagatag
    36841 agcaactgga atacctgttg tagctgctgt taatagtact cctaacattt gcatataggt
    36901 tatattttta taatttcctt ttttagctcc atcttctgct ttatgaacta gccatatacc
    36961 aatagtattt ctaagaacat ctaattgtac catcaataaa gcaactggaa tacctataga
    37021 gattcctaca gatgcttctt gcttagtcgt aatagttata aatgtggcta ctatacttgc
    37081 tgtttgataa tcaggtattg atgctccacc aaagttacta atacctaatg ataatagctg
    37141 taatgtacct ccaatatata accctgtatt tatatctcct aagataagac cagtaataaa
    37201 acctgctgtt actggttgat atgttccaaa cattgttgaa tttttttcat agtttataaa
    37261 aaatccatat agtacgatta ataataattg ccataattgt ggctccatta tgatttcacc
    37321 tctcccaaaa tattttttag ttctttaaaa ttataactgg aatcttgctt taggaaaata
    37381 ggaatttctt ccagtgggca ttcaacttca taagttttcc caccttcata actaactcca
    37441 ctaaatatat tttcccatgt atgtcctttt ggtaaatata cttttctact tctatcttta
    37501 taattcatta ttggagctac taaaatttca tctccaagca tatatgtatt atccacctcc
    37561 caagttttat catcttcagg aaattcataa aataaagttc tcataactgg tgttccatct
    37621 tcatgcgctt ctttcatcag tttttttaaa taagttttta agctctctct aatttttatg
    37681 aattttgtaa gaattacttc aacttcttca ccataagacc atatttcatt aggagctcca
    37741 gttaccattg agcctccacc tttatttgat aatggtttac tatgaggcaa tctatctcca
    37801 tgcattctca aaattggtga aaaagtagca tattggaacc atcttaccat aagttctcta
    37861 aattctgggt ctttaggatt tcctccatgg aaacctccaa tatcagtagt ccaccatggt
    37921 atacctgcca gtcccatatt taaccctgta tttacttgat tattaaaagc ctcaaaacta
    37981 gaatcaatgt caccagacca tactaaagct ccatactttt gagctcctgc ccaagctcct
    38041 cttacaagag ttacaacaga ctctatgtca ttatgtaaac catcataaat catttttaaa
    38101 taatcaatag gataaatatt accacaactt aaaacatttc cttttttata tctatagtta
    38161 tcaaaatcat acacagaata gccaggttca gctacatcta accaataata gtcaatccca
    38221 agttgtttat aatttttatc tattctatcc caaacatatt ctcttgcatt ttcatttgtc
    38281 atatctacaa agactgtatt tccttgaatt tgcattgtca ttctaacacc acgattaaca
    38341 ttgactaaat agccattttc taaataatca ttgtagtttt ctgcatcact ttgaactgta
    38401 ggccatacag atactattgg ttctactgaa tactcttctt tcaatttttt aactaattct
    38461 ttaggatttt tccaataatc taagtcaaat ttatattcac cttgcttagg ccaatgaaaa
    38521 tagtcaattg caattgatga aagcttaatt cctcttttag aatattcctt cacaacatct
    38581 aaaacttctt ctgaagttct atatcttagt ttactttgcc atagtcctaa aaggttttca
    38641 ggcatcatag gaacagttcc agtaacttga gaataatttt tatttaactc ttttgggctt
    38701 tctccacaag taatccaata atctataaaa tttgtagaaa acatcttcca ttctgtcata
    38761 tttttagcaa aagatacttt tccaattccc ggattattcc ataaaagtcc ataacctaga
    38821 ctagaaatat aaaaaggaac tgatatttga gaatttcttt gggctaactc caaaacagta
    38881 ttctttaaat ctaaaaattt atgttgatat tgtcccattc caaaaatctt ttcagaaggc
    38941 tcagattcaa atctagtagt tacttcaaat tctccactat agcttggtcg atattctctt
    39001 gattttaact ttagagtaga gttaaagtct ttggtaatct caattgtccc tacatcttct
    39061 ccaccatcat catgttttac agctcttaat cgaatatatt ctttcaataa tatttcattt
    39121 ttatcattat aaaaagtaat tctatctcta tggtctaaga cagcttttat ctttccattt
    39181 ttaatgattg cacttccatc ttcattttta ttaattgtaa tatcatcttt atttaactta
    39241 ggtttttcgt taagagcata gttttcatca acaaaatttt ggtctacaaa cgacctaata
    39301 cgtaaagagt tttttcccca tgcttctatt cgcaatagtt cattgtcaaa tcttttttca
    39361 atatagtctt cagatatttt tatcacggct acctcctaaa tcaatggtat aatattctat
    39421 ctttgtgtag cttaagttaa ataatgtcgt ttagtatcgt tatttataaa ttaggtttta
    39481 tatataattc atttgtacat taaactaact taccaataat atactttatt tgactttgtt
    39541 tgtcaatcgc tttccggatt ttagtaaaat tttctaatat gttgcttgaa agtcgttctt
    39601 aatatctttt atttatactt ttaatatctg tgatgatacc tatatacatc tagttttttt
    39661 aaaacacata cagaaataaa gtttgcctat tatgtagata atatcggact tgaaaatatg
    39721 tatagtgacc ttataaatac agataataat atattagata ttgttcaaaa caatggattt
    39781 tataattata aataatttat gaaattattt aataaaatat ataattgtat accaagtcaa
    39841 aaacgacaac aaataaataa aactaaaaaa gatgttgtct caaaatatag ataaatttat
    39901 ttttcattgc taaaatgatt aaaatatatt tgatttaata tacttgattt aatataaaaa
    39961 aagagtgtct cataaactaa aaagttcact tttagacact cctttatata tattatctac
    40021 ttcttaattc atttattacc tttctacatt ttctttcagc tagtggatac atctttataa
    40081 gtactaatta ctccacttaa aaatggttcc tgtactgtcc atcagtcata tttttctgcc
    40141 aaatataatg gtgtttcata atgagacaat aaatatttat atctctactt atcttctcta
    40201 agctcgtcaa atccaactat aggtatctct aaattatatt ctttaagtag cttttctagc
    40261 tcttctataa aaataccttt cccatccacc atttgtatat catttatttt atccatcaat
    40321 tcattgcaac cacttaactc accaaaccaa cgtttagaac tacatgtctt attataacca
    40381 caacttggac tgccatctat tgcaatgata ctttttatat cataatcatt ttttaaatat
    40441 tcatcaaact gccttacatg aggtattaac atttgcctac attgttctct aaaaaacaaa
    40501 ttgtcaaact gttcttttac atgtccccac ctatttattc catacataat catttctgga
    40561 catggtagtt gaattattcc atacccttta tttattaaat ctattgctat attttgtgct
    40621 cccttaaatt ctgacaatcc ctctacttta gaattacaat ttaatataca atgacatact
    40681 actacaatct ctctatttct cttcataata atctccttag ttattcttaa ttttaatgat
    40741 actacatatt ttgataatta tattatttat ttgttctata tttccaatat tctatataga
    40801 aatatacaat tagtaatctt ttataatcta tactatgata aatgtatata tttttttagg
    40861 aggtattata attggatact aaaaaagtca cattttcttc aatgtgcata gttattaata
    40921 ttgtcttagg tatggttata tctatgataa atataccatt attattttta gatacagttg
    40981 gtactgtact tggggctgtc gtattaggtc ctttttgggg tgctcttatt ggtggatgta
    41041 caaacttagt tttaggtgtt atatcaggtc ctacaaatat accttttgcc cttgtaaata
    41101 ttgttcttgg tcttattgtt ggatatattt ctaagaaaaa aggttttggt tataaagaag
    41161 ctattattac aggagtaatt ttatctattg tttgtccttt aattggtact cctatttcag
    41221 ttttattgtt tggtggttta agtggaagtg gtgctgattt attggttggt tttttagttc
    41281 agtctggtca gaagatattt actgctgcgt tctttccaag gattcttagt aatatagtag
    41341 acaaaccttt gtcttgtatt atggtggtat attttataag taaaatgcct aaaggtttta
    41401 taaaacaata tagtaaaaat acttctagtt catattaata aatcatttat tatgtaaggt
    41461 ttattactct ttaaaatgct atatactcat ttttatataa catttttatt aataatttaa
    41521 ttagatagta tttgtattac tttaattaaa cgtaacctct tgatataaat ttgagctata
    41581 aatctatatc aagaggtgct attttatttt taatataatt aatattctat tacgcaaaaa
    41641 atgcatatat ttcattattt tatggaaaat attacttcat ttaactctat atcaaactca
    41701 ttaagtaaaa atctaattat atttaattta gcctctgtat ttaaatttgt ttctaaatat
    41761 atattttctg atattttaat accttttctt aatttatatg catctctaga cttaatatta
    41821 tctataaaat ctcttttata agttttgtct acaatactgt taaaccttac agaatccaaa
    41881 tcatataaag taagagcaac ttgttcataa aattctgtcc aatttttagc cttatatgac
    41941 tctcctaata tactaaatga tactatactt tcatttgtaa aattaacatc atcatcctct
    42001 aacgtaaata tattttcact gttacttgga ggttcatatg taacacttgg atatttccaa
    42061 atttctacag ctctatctag taatatctta gttctatttt ttatttcttc ttcattccac
    42121 ttatctatag atgaaatata tttatttaga taaagtctac tatctttaaa tccatcttcc
    42181 atttctttct tttcttcaaa tgttttatta cttagttttg aattatatcc tgtcaaagtt
    42241 aaatttccaa ttgtatgtaa atatttatca tgtatctcct tatagttatc tcctagtgat
    42301 tccttccatt tatttgttaa tgtctgtggc attatatgct ctatatttag catattatta
    42361 ttgattaaat tttctaaatc aacaatttct ttattattat aattctctaa cctctcaagt
    42421 atatataact tattctttga cttagtatta tatatatctt tagtttcaaa agcatttgaa
    42481 aattcactgt cagtaggaaa tctttgagat gatttcttat ttataaaaat atatcttaat
    42541 atattagaat agttttcttt ataatcacta aattttttaa tttcccttcc taagttcata
    42601 aatactttat tcagtgcatt aggaggtaca tcacatacta ttcttcttaa tataaaacat
    42661 tctactaaat taagggattc tacaagtact tttttattta ttataccttc attataatca
    42721 tcaaataatt ctaatataaa cggatatgat acaaatattt caagtttgtt tatccttttc
    42781 aaaactttgt ttacatcatt atcatcagta catgaataag atatctctct ataatagtta
    42841 gaaaatttaa gtaaatcttt taataaaatt tctatatcta taccattatc tgatacatac
    42901 cttttaaaac taaaatatac tttattttta ttcggtatac ttctctcctt tatagtcaaa
    42961 tagtctctta taaaactact tacgttgcta cttgtatttt tttcaatttt ataccaataa
    43021 ttattataaa attcctcttg taacttagag cttctaccca ttaacacaaa gtttcttact
    43081 ctatcagctt cacttaaatc taagccagtt gaatttagac tttcaaagat taattgaggg
    43141 tcatcttcac cattttttaa ctctatttct actatagtta atttctgtat agcatcaaac
    43201 aaatcatcta ttgatatatt atcttctttt attctattat aaaaatataa ataatttgaa
    43261 actatattag aatttctatc tgtattcatt tcttcttcaa atagttcata gtacgctttt
    43321 ctatcttctg ctattggttt taactttatt tttccatctt tatctcttga gtgcttgttt
    43381 ataagataac actccttaat ctgttcttct gttgtaataa ttccttttga ttccccaaac
    43441 tcttttatta tttgacacat ggcaatcaat aatattgaca cagtagtcac tctttgttgt
    43501 ccatctatta ttaaatattc ttttcccata ctatatatag atacaactga ccctaagaaa
    43561 tgagttctaa atccagaatc tattatatcc tctaaatcat caaacaatct tttacattgt
    43621 tctttcttcc agttataatt tctttgatat acaggtacta caaaactttt gtttgacccc
    43681 tctaaataac taagaaattc aatttctcct gctttcatat taactccccc tataagttaa
    43741 ataaattcca ttcataactc catgtatcta tatattatat caaaattttg actcataaat
    43801 gtatatgaaa gccttattat ataccttttt atacctgttt ttattttatt aaagtaaata
    43861 catgattatt ctataaaata tacaaatact taattttaaa aattattatt taatcttctt
    43921 catgagtaat tcatagttat ttatcaatta aaaagagata ttgcataatt attcaatacc
    43981 tctctttgta tatttacatt atccatatct agttatctat ttcaacccaa tattagacta
    44041 cctactaata aatttattct ctacatcatt aacaataatt ttgcactaaa taacatcatt
    44101 agcctatctc tgatgcattt tctttaattt tatttatagt tttaatcaat ttatttctct
    44161 cttcaatatg attttcaaat aaatcaatta tacttccaac agttctaaat gggtcttcca
    44221 tcaacacttt gttatcctct ataaatccat tcttgactac ataatcgact ataagtttaa
    44281 caaaatgtat ttgcttagta ttaaagctct tattatttaa aaactctgaa aaagcttcat
    44341 ttgcagcttc tctatccaat cccactagtc ttctcactaa ttggcttact ggagtatctc
    44401 caaactcctt cttataatca tcacaattac ctaactgttt taagagtatt tcctccaacg
    44461 tttcaacatc ttgctttgtt atctttttat tatttcttaa tttaaatatt gctaattcat
    44521 ctttatggct atttaaataa tactctacct tctttttata attcttaaga ttgtttgcat
    44581 tatatacaga atcatttcta tcttctgcta caatcatatc ttcaaaactt gtataatata
    44641 tcttttgact agacttttca agatacttaa taagctctct taatgatata cgtacttctt
    44701 ctacctcaaa tatatctgaa tcttcccaaa aatcctctgt cattgctttt tcaatagtat
    44761 atttttgttg ctgaatctgt ggtatagtcc caagttttga aagtttttct gctgtagcca
    44821 ttacatgcct tataccttta cttgcattat tattttgtaa gtatgcaagt tgtatattat
    44881 acataactac atcaaatctt ttagccaatt catcatcact atatgaagtt atgagtggtg
    44941 atatatattc tcttatctca ttttgtgcta ctgctccaat attgctccaa acattttcat
    45001 ttttatactt atgtacataa cttaaattca tcctaactat ataactatcc tcatttaaag
    45061 cttttacaga agttataagt tcttctaaca attcttttct aagttctgca tactcacctt
    45121 ctatatattt aatatcttga agttctttaa ccatacttac ctttatatta aataattttt
    45181 cagtaagtgt ttctgcttta tttccctcaa atcctttagg attaaattta aaaaattcaa
    45241 aattattaca aaaatcaaat attaagaatc tctccttatc catatcaaca cctaataaat
    45301 ctggacataa tctagttcct ctacctatca tttgccaaaa cttagtctta cttctcactt
    45361 tcttgaaaaa aacaagattt agtatttcag gtatgtcaat tcctgtatca agcatgtcta
    45421 ctgaaactgc tatttgaggt aatttattct tatcagaaaa atcatctatt atagaatcta
    45481 cataatttat actatagtca actgctttta caaagttccc accatacttt ggatacagct
    45541 tattaaatct ttcaactatt gccctagcat gctttgtatt ctttgcaaaa attatagtct
    45601 taccaatctt ttcttgtcct tctattttca acccctctgt cattagctta tttaaaacta
    45661 aatctattgt gtcagaatta aatagccact catttactgc attattccct atttcgtctc
    45721 caatactctc atcatcatta aatgtatttt catattcttc cttctcttca tcagaaagct
    45781 catcatactt aattccatct tccataatct tagtcttaaa ctcaatacta gtataatcta
    45841 ctaaatatcc atcctcgact gccttattat actcataagc atatgtaggt actccatttt
    45901 ccatgtcaaa aactgaataa gtatttttat ctatctcatc ctttggtgta gcagtaagac
    45961 ccattaagta agaatcaaaa taatcaaaga ttgacttata ctttttataa atacttctat
    46021 gcgattcatc tattataatt aaatcaaaat gaccaggtgt aaacaatctc tttccatcct
    46081 tagacttcgt atcatcaatt gcattcatca ttgttggata tgtagaaaat atcatcctag
    46141 catcttctgg gctatctttg ctatccaata aattacataa cgccaagtta ggtaatagct
    46201 tagtaaaact ttttttagct tgctttacca atgcttttct atctgctaga aataatatat
    46261 ttttaatcca attatgtctt gaaagtacat caactataga tatagcaatt cttgtttttc
    46321 ctgtaccagt agcacatacc aaaagagttt tgcgttgctt attttcaaga gcctcacata
    46381 cagccctaat agcttctttt tgataatatc tattggatat ttcatcattt attgttacag
    46441 aagttaaaga cttcttactc tttcttctat ctatcataag ttgtaattct gattttttat
    46501 aaaatccata aactttccta tctgaatagt catcccaaat atacatatca aaaccattag
    46561 tcaaaaatat taccggtctt tgactatatc tcttttccaa acaatctgca tataatttag
    46621 cttgttgttg accaattttc gggtctttac tcgttctttt cgcctcaact actgctaatg
    46681 gcttaccatt ttcaccataa agaacataat ctacatatcc tacaccactt tcattaggca
    46741 taccttgtac ttctatttct tcccatatat cttttccaaa ttcccaacct gcaagcttta
    46801 attctatatt tatatatctt tttcttgtct caaattcgct tacttcgtct atcttgaaat
    46861 catagtttgc agtattaact tttctctttt cagttagtga ctttcttaat tcctcatttt
    46921 cttttattac ttcttcaagc tttttatctt ttgaacttaa tctctcataa agatttttaa
    46981 gttcgtctgg tctcgtcctt ttctcttccc catgaagtaa taaatcttca ttaaagtctt
    47041 ctgctgtata ttcatctgaa taacaatagt ctatccaact aacaaattga tgcaaattgt
    47101 taagtgaaag tattgcttct cctctctcta tgttcgcact agtatgtaca gataaattac
    47161 ctaatttaac tatatatttt aataaaggta acatatcata gtctataagt tctataaaac
    47221 tattattatg aatcaacgta ctgagattat cttgataagg caatactaaa tcactatcat
    47281 tagcatatag ccattttact gcaagctcta aagctcttct tgttatagtt gcacaagtag
    47341 atggactaac tagtatactt ttttctgctt ctaagcaagc agtattaaaa ctattgaaat
    47401 ttttcttctt ttgtaaaaaa tcaaaattac ccaagctttt atcccccttt tgtcccttag
    47461 ttaaaataaa tctctctaaa aactatttct tacagctgtt tcttatacta acaaatactt
    47521 cttcattttc tgtaaacaat tcgtacatat cttcaaactg tggtatatca tatccatgag
    47581 aatcatcatt tctcaatttt ctaagtgttt ctataactat agaagaattt ttaggtaata
    47641 aattgtgata ctcacaagct aaaaggtagt cataaaagtt tttagatttt atgtttaaat
    47701 caattgattt ataatacaac attgcttttg ttaattctag aaatgatacc atatagcttt
    47761 taaagccttc ttttatgtat ctagcccata actcaggcat ttcttcctta tcatataaga
    47821 ttttgaagtt ttgcaggtca tacaagcaag aaccaaaatc cctatttact tcttctattg
    47881 agttccaaga taatttgttt ctaattacca tacatgtccc tccaatctaa gatatctatt
    47941 acatcactgt tttcaaaata gaatttattt atataatcct taaaatcttt agattcataa
    48001 ataacttcac cttctaaaat agctttttta agtgctattg tataattatc tgtaacaatt
    48061 tttaggtcta catcaatgtc taatatattt cttagagctt ctgtcttagt tgcaagttct
    48121 gtaattggta cttttttgat aggaatccaa gctatgtcta tatcactttc tgatgtatgt
    48181 ttatctgttc cataactacc aaatattatg attgctagag tattttcttt tggaaataca
    48241 tttattattg agtttttaat ctcatttggt atatttctca tttaatcacc tcttgtttat
    48301 taggtaatat tacttaatta aatttatatc cataatcttt taatctattt atacatattt
    48361 ctctttcttc atcagtaaac aactctttat acttttcttt taatactaat acttctaatg
    48421 ataaatctaa tctcttacac tcccatagtc ttgtaaatcc ttcagtagct ccttctttat
    48481 tgattaattc tttagcagct aataaggctc ctttgttatt tatcagttgt aaaaatcttg
    48541 ttggcttata gttacattgt aaatcagctt ctttatagat atttaccatg ttatggtata
    48601 aatctagctc tatttgattc atagatttta ttcccccatt ttaataattg tattttagtt
    48661 gaataactct cctttaaaag ctttttgcat taatgagtta aagttgtctt ctagttcttt
    48721 taagctagtt tccatttcaa acttcaaaga gtttacttgt ttaacgaagt tggcaaattg
    48781 attttgaagt ctaataggag gtacaataat atttattttt ctaacagcat ctttagttat
    48841 cgtttttgtt acagctcctc ttactttctc ttttatttta ctttccatat aggatgttag
    48901 taaaaggtta tataagaata tatgattcac tttatcttca ttaaatctaa gcataaattg
    48961 attcatagct aaagatactg gtttatttaa aaatggcatt aaataaactt tacctgcact
    49021 acctatctta tttattataa cctcaccacc aaacaccttt gatttttcaa gataattata
    49081 tgcatgttca tcgatatact taacaccttt ttcaaagtta ttattttcta aatctgtagt
    49141 tcttaccatt aaggcataac cttttgtatc taaaagagtt acattatctc ttaaggtttc
    49201 ataactacca tttgaatgat aatcagttaa aacatctaaa tatttcccta tttctgaaat
    49261 ttcccagttt ttttcattct ttgatggagt accaaacatc tcaataaatc ttgatttaac
    49321 taattcatcc aatacttcta tttgctcttt tcttttatct attaactctt gagccttgtc
    49381 taaaacacgc actacctttt cttgcacttt taaattatac atgcgtattt ttatattagc
    49441 taatccttca ttatttaaag ctgattgtgt agcaccttta cttaacctat ttttttgatt
    49501 tagaaaataa ctactattta agtaatggta taaatattga ggcaatattt cttttgatgg
    49561 ttttaaaaca taaaatccag tcgatactat tatattttta ttagttttat taataactaa
    49621 tgttttcttt gtgtccttca tttttgcaaa tataacttct cctatattta cagtttgatt
    49681 tgctctagaa ggtttatttt cataagtaac tatttctaga ttgcttatct tgttaaaatc
    49741 taagtttcca gtactaagat atgagcgttc tccatcaaac ttttttacat tttccccgct
    49801 tatactaaca acatctaaaa tttttgcttc atcaaccata ctctacacct ctaacattct
    49861 ttctagttcc tctaatccat ccactatctc tttctctaac gccttaaccc tacccataat
    49921 aacactagga gcatcataaa ctacttcttc atacactacc tctttatact tattaataga
    49981 taaatcatac ccattctctc ttatctcttc cacatcaaca aaaaaacttt gctctgttct
    50041 ttttctatct acttcaccat caagattatc aaatctctta ataatatcct ctatatcact
    50101 atcctttatc tcatttctct tatcatccaa agaataacca tcagctttca tatcatagaa
    50161 ccatacctta tcagttccac ctgttcctgt tttagtaaat atcattatag ctgtagatac
    50221 tcctgcataa ggcttaaaca ctccacttgg cattgatatt atagcttcca atttatgatt
    50281 atcaactatt tcttttctta tcgatttatg tccacctgtt gaaccaaaca atactccatc
    50341 tggcactata catgcgcatc ttccaccaat ttttaaaact cttaaaaaaa gtgccaagaa
    50401 taataactct gttttctttg tcttagtcac ttttaataaa tctgctgaca ctgcttcata
    50461 atctaaactt cccttaaaag gaggatttgc taacaccaat gtaaacttat ctttatctgt
    50521 attaacctcc gataaagaat ccttatactc tatattagga ttgtcaacgc catgcaacat
    50581 catattcata gcacctattc taagcatagt tctatccata tcaaatccat agaacatacc
    50641 attattaaaa tgctccttca gcccttgcac taagaaaaga cttgaatgat tatcccttaa
    50701 gtattgttgt gatgatacta aaaaacctgc tgaacctgct gccgggtcta ctataatatc
    50761 ttctggtgtt ggtttaataa gtcttactat catatctatt atgtgtcttg gagtcctaaa
    50821 ttgaccatta gtacctgctg tagccacttt ggataataaa tactcataca aatctccctt
    50881 tgtatctcta tccttactta attctaaatt actaatacca tcaactattt tagataacat
    50941 aagaggcgta ggaattttaa atattgcatc tcccatgtac tttgcataag ctgagtcttt
    51001 atttccatgt aattttttta tgaaaggaaa cacttcattt tgtactattt catacatttt
    51061 ttctgaattt ccttcattag aaaacttact ccatcttaaa tgttgatgtt catcattaaa
    51121 tatcctttca aaagaaactc ccaaaagagt tgcttctgct tcattttttg tttctacttc
    51181 atccaatcct ttaataaata aaagatatgt aaattgttct ataacttcta atggattagt
    51241 taatccacca gtccaaaatg tctcccaaat cttgtctact ttgctcctta attctcctgt
    51301 aatcatatat gactttccct ccagtgttca taaaataatt taaatatata ttttagtcgt
    51361 acgccttaat agttagtgtc ttatgttaaa tccaagtttt tactacacag ttattaaatt
    51421 atttttccta tttacatgtt ttagttaaaa aactaatgca atactcttat tttatgatta
    51481 ttatatatac catacaaaat tattttatca tatatccatc atagaagtca tctacctgga
    51541 taattcttac catattataa ctttttaata ttaatttaaa cttagaaaga acttttttat
    51601 ttaattatat catcttcctt atttcaaatt tctcaattac aatattaatc aaaaaataaa
    51661 ataagatgct gtctcaaaat agatataatc ttctttttta ttgtcagaat gatgaaaata
    51721 tatttaattt catacaaaaa agagtgcctc atgaactaaa aagttcattt tgagacaccc
    51781 cttaatttaa tcttacttat tctttccctt tattattaac acttcactgt ctctattgct
    51841 tttcctacac atccacaaac ttccatccta ctcttaacaa aatctttaac tgactctaaa
    51901 ccttttttac catatttctt agggtcaatt acctctgggt cagaattaag cacattctta
    51961 actccattgc tataagcaat ccttaattca gttgcataat taaccttgca aatccctctt
    52021 tttatagatt ccttaataac ttcatctggt attccagacc caccatgtaa tactaatgga
    52081 actgatacaa catctctaat ttcagataat ctatctaaat caagctttgg ctctccctta
    52141 tataatccat gtgccgtacc tattgctact gctaaagatg atacccctgt tctctctaca
    52201 aactcttttg cttctaatgg gtctgtatat gctcccccat caccaccatc taaatcgtct
    52261 tccttacctc caactttacc taattcagct tcaacaggta tatctgaagg catacatgca
    52321 tctacaacag atttagatat tgaaatatta tcttcataac tttcatgaga accatcaatc
    52381 ataatagaag tatatccaac tctaagtgcc tgcatagcta gtccaaagct tgaaccatgg
    52441 tctaagtgca ttgccacagg aacacttgcc ttctctgatg ctacctttac attcgctaaa
    52501 taataatcta gtcctgcata ctttattgtt gaaggtgttg tttgcaatat tactggtgat
    52561 ttaagttctt cagcagcctc tattactgcc ataaccatct ccatattttc aacattaaat
    52621 gcacctactg cataatgccc ttcttgtgca tctaataata tttgtttagt tgtcactaat
    52681 gccataattt ctcctcctat atgtttatac tgatttaatt tcttcgttat ttaattttga
    52741 tactatttct ctacttgttt tgctatttaa taactcattt aaaaattctt cattcattaa
    52801 ttttgaagat agttgagata atgtttttaa gtgtaaatta tcaccattat ctgtagctgc
    52861 tatcataaat ataatatgtg ccaagcttcc atcttctgat tcaaagtcaa acccttcttt
    52921 tgatacacct actgctacac gtggtacctt tactgcatct gtttttgcat gtggtatcgc
    52981 tatccccata ccaaaacctg tagatgatat ttcttctctt ttaaggattt cttctttaaa
    53041 cttcttttta tctaaaagaa caccagattt atcaagtatt ccaatcattt catcaattac
    53101 atctgtttta ttttttccct taacatctaa aattactgtt tcttcgctat ataaagagat
    53161 attattagat acgttttccg attctgcact ttcattttta tgttcatctt ttgttgcatt
    53221 tgtattttct atagtatttt tctcatttac tactttaggt gtaaccatca tataaagtac
    53281 agcacctact aatgaaccta caaatataca ccctacccat aaaagtggct tattgactaa
    53341 tcctagaacc aaaaaccctc catgtggagc tggtacttct attttcatta tataagttaa
    53401 aattgatgat attgatgatg caatcataag tactggcaac acttttaatg gattttttgc
    53461 tgcaaaaggt attgccccct ctgttatatg agtactacct agtatataat tgattaatcc
    53521 tgctgctcta tcttcttctg taaatctatt tttaaataaa gtagatgcta ttgctattac
    53581 caatggtggt gttatacaag ctgcagatac acctgccata aataaataat ttccctgtcc
    53641 tagaagcata gttccagtta catatgctgc tttatttact ggacctccca tatcaaatgc
    53701 tgacatacat cctattacta ttcccaaaat tataggactt gaattttgta accccgatag
    53761 aaagttcatc atagcattgt taagtgctga acatggccca ccaagtaaca acattgctac
    53821 acccacaaga cctacgctga caataggaat tataaaaatc gatttaagac cttctaattg
    53881 tcgtggtaat tttcttaaca aatgtacaaa tagtttaact aagtaacctg ctaaaaatcc
    53941 tgatatgatt ccacctaaaa accccgaacc tgtatcaaat gatatcattc ctccaacaag
    54001 tcctgccaac ataccagctc ttcccgatat agattgagct ataaatgctg ccaatacagg
    54061 aaccatcaag ttcatagaat atccaccaac agattttaat gtagctgcta tttgattata
    54121 ttgttctgaa tttgggtcaa atgaataaat cccccataaa aatgatatag cagtaagtac
    54181 tccacctgct actactaaag gtaacatgtg agatacacca ttcattaagt ctttatacaa
    54241 cttttgacca aacgataaat ttccttcttc tgcaatttta ctgcttgata agtttccttt
    54301 tctaatagct acttttccat caatacatct ttgtataagt tcattagctt tatgtatacc
    54361 ttctttgaca ggtacttcta ttactggctt tccattgaat ctgtccatat caacattttt
    54421 atcacaagca actattattg catctgccat ttcgatatct tttgctgtta acttattttc
    54481 tacacctata gctccattcg tttcaacttt tatgtcacac cctaattccc tggctgaatt
    54541 ttttaatgct tcttctgcca taaaagtatg agctattcca gttggacaac ctgttacccc
    54601 tagaatcatt ttctttccca tttttatacc acctttctga ctcttatatt ttttatataa
    54661 tcttccacat tctccaaatt acctatacca ttactttcag ccacacttgc tcctgttgct
    54721 gctgaccttt ttaatgcttc ttcaatatgt tctggatttt ccaaccatat acttaaaaaa
    54781 gcagctaatg cagaatcacc agcacatgca gagctgacta ctgtaactgg ttgagcacta
    54841 gcataataaa ttaattttcc attataaaaa taagaacctt tttctcctaa agttagcaat
    54901 atattttgag caccttttaa atgtagtaat ttaagtacat ccttaatatc ttcttcatct
    54961 cttacaataa ttccaaatat atctttgatt tcttcatcat ttggttttat caaatatgga
    55021 ttatactgta gtaactcctt taattttggt gaacttatat cgagtattgt ctttatactt
    55081 ttatttttac aaattttaaa tatatcctca tagtaattat catcaatacc aggaggtaga
    55141 cttccactta ttgataagta acttatatct tctaatgact gtatcttatc tagcatatct
    55201 agtttttgtt tttcatttac atatgaccca gagtttacaa atttaaattc atcacttcca
    55261 tcatttaaaa atatatttat acgagttgta tcttctaccc aagtaggcaa tacgtcaaat
    55321 cctctctttt cgctttcttc aactatatat tttcctgaaa atcctccaaa aaatcctaat
    55381 atcttagatt ctataccata atgacctagt acaaaagtta catttaatcc ctttccatta
    55441 ggagaatata cagcatttga tgtacgattt actaattttc tctttatccc attagtagat
    55501 atattcatat ctattgcagg attcgtagtt aatgtatata tcattgtctt cccccttgct
    55561 cgtgctgtgt atgttttcat tataataaaa aagtctatga aaatcttttc acaaatagaa
    55621 aatcgatttt catagacttt tcaatttaat tttcagaatt attatatctg accatataat
    55681 ctataattat cctagatata atatacaagg gcaatctgga agatacttca tattcagaaa
    55741 ttgatatatg ttcatgtttg tatcctacaa tatataaatc cgaatacttt ataagttttg
    55801 cactttcact acaacagcaa gttataacct tagctccaac taaattggca ttctgtgctg
    55861 attctacaag ctctatggta tttccattca atgaaaatat aattataagt tcgtcttttt
    55921 ttattgattt agattttatt ttcattatgt tggggtcatt tataaaaaca acattaaaat
    55981 caagtaattg caatttaaga ctaaactctt ttgctacata ttcagtaagc cctcttgcca
    56041 aaatatatat cttactagat ttatttatag tttttattat attgattagt gtagttaaag
    56101 atatttgttc tataactctc tgtgcttcta taaaggattt atttattata tcccccatat
    56161 tttgtatatc atcattttca tcttttactg ttaatctata cctaagttca ttgaatccat
    56221 ttaaaccaca ttttctaatt gctcttgaaa cggttgctgg agatgaatat gtttcatgag
    56281 caatctctac tatagataat tctggtaata ttgattcatt ttcatttata aatttaatta
    56341 tttcaagttc cgtcttcgtt agattttcag aattactttt gtttagctca attatcatat
    56401 gttatctccc cttatataag ttttatttgt ctaaatttat cgagtaatat aatatattac
    56461 ctcttaacta cttattttta tatacaatta agatttagtc aatgtctata tatgtaaatt
    56521 tataatataa taattttttg cttaaagttt attatgttat cttatagcat tttaaaataa
    56581 aaaagaattg tacctctacc aaaatttgga tgaagtacaa tagatattcc tcatactgat
    56641 atgtttatga ttaaaagtat aaatataaat ttcgctatga atcatataat taataaatca
    56701 ttttatttac aattataacc ccccttataa aactatatta ataatatata cagtatttat
    56761 aaggggggtt gtttatattt aaaaactatt tacttttctc ttaattcttc tccattagtt
    56821 cttattacat tttcatacca ataaaaacta tcttttttat aacgttcttt acttccattt
    56881 ccattgttat ctatatccac atatataaat ccatatcttt tttccatttc ttgagatgaa
    56941 caacttacta tatctattgg tgaccacata caataagcta atatttcggt tccatcagct
    57001 atagcttcac ctatttgttc tatatgtttt cctaaataat ctattctgta actatcatga
    57061 acttttccat cttcaaattt atcatgcatt ccaaatccat tttcagctat cattattggc
    57121 ttttggtatc tatcataata ttgagataaa gtattgtata atccttttgg gtcaattgcc
    57181 cacccccaag gatttgcttt taaatatgga ttctttatat tgtcagttgg attcatggtg
    57241 tttttacttg ctgatactgt tgtagaataa tagtatgata aagctagaaa atccatagta
    57301 ttttctttta agattttatc atcaccttcc tccataacta tatttatgtt attttctttg
    57361 aaaaatctct taatatatac tggatactct cccctaaaac ttacatcagt gaaaaaatat
    57421 tgtagcctat ttctttttaa agcaaatact acattttcag ggtcacaatc ttctggataa
    57481 gatgtacaat ctgccatcat catccctatc atcatatctg aatttatttc ttttccaagc
    57541 ttcttagtca aagctgtagc tatgaattga tgatgaatag cttgatatct agcctcttct
    57601 acattatcta cttggtctac acaaaatgca actgaattaa atgattcata atgtattaaa
    57661 tttatttgat ttataactat ccaatattta actttatttt tatatctatt tagtattaat
    57721 tctgcatatc taacaaagaa atctaccact tttctattag accatccttt atattttaat
    57781 actaaattca aaggagtctc atagtgaagt agtgttacaa taggttccat accattatct
    57841 attacttcat ttataagatt atcataaaac tttaatccct cttcattagg ctctaaatca
    57901 tctccatttg gaaatattct agcccaattt attgaaaatc taaaacactt taaccctagc
    57961 gctttcaaaa gctttaaatc ttctttgtat gtatgataaa agtctattcc actacgctta
    58021 ggatagtacc catttttatc tttcatagca aactttattc tttctatagt catatcagac
    58081 tcataaggtt tagatatatc tctatcttta tcatacatat gtacatcagc taaacaccaa
    58141 cctttgccac cttcattcca tgcaccttct aattgattag ctgctacagc tcctccccat
    58201 aaaaaacctt taggaaactt acccaattta atcactcctt attttattta tttaaatcat
    58261 ttactattat ttaccttata ttctatagac tttactattc ctactaaaga catagttata
    58321 tttaactcgc tgaatatggt cataagagta tcttgagcat gtgcaaataa cagcgaatgt
    58381 gctcttttct ctccaccagc ttccccttgt ataatcttgg tttgagctct atgtgcttct
    58441 gtcataaacc cttttgcttt agctagtttt aaatcagcat ttctataatc aaacttttcc
    58501 aaatcattaa gagcatgttt aatttctgtt ctagcctcac ctgcacgaag tattatttgc
    58561 attgccacct ctactaattc ttcatctatt atatgttctt caattgtcat atttataatt
    58621 tcctttcaat ttctaaattt aaacctcttg gctctctaat tttatctctt ctttctcata
    58681 agctttaaaa aatggatacc atatcataaa tagcaatact atatttattg ctaaaacaat
    58741 aagacctcta acatcttgat ttaccataaa agtagatata ccaaaaggaa cataccataa
    58801 attaaacacc ttacttggaa ttgtcacaaa tcccatactc attgataagt aagtagttat
    58861 tgatattact actgttccta tccacatagg taacattaaa aatgggttcc atgccactgg
    58921 agctccaaat attactggtt catttatatt cattatagaa gggacaatac atgctcttcc
    58981 tattgctttt attcttccaa ctctggataa acacatcatt ataactaatg gtaatgtagc
    59041 acccaaccct cctaaagtta tccaacctgt ttgaataact tcgtaaacat atatattagt
    59101 tgctactcct cctgatgcta ctgctgctgc attagctgca attgcaccaa gttgaattga
    59161 ataagttata ggagatagta cccacccact tattcctaaa gaatatataa atactactaa
    59221 gaagtttaag agtacaaatc caggtaatgt ctgtgctata tctgatactg gtttaaatac
    59281 tctaactatt atttcaaaca tgtcaaagtt gagtccataa attaatcccc agcctacaaa
    59341 cattatcact gttataggta acatattatc aaaccacttg cttacaaaat ccggaagtgc
    59401 tgaatcttct ccgaaaaatg aaaaagaacc aaataaagac attattaatc cagagaataa
    59461 tcctgcaact agcgatacaa gcattccttc tcctccaaac ctgttgaagt taaatatagc
    59521 tccttcattc gtaatctctg gacgaatcat cattaacatt aatccagcac ctgcaagacc
    59581 agctactaca ctcatacttt caaatttctt attcttcatt atttccatag gcaataaaaa
    59641 tgctataaat aatcctaaaa gtccaaatgt atattgattt attggactta aatcaggtaa
    59701 aaagcttatg taattcttca agacagaaac tatagttact aatgagccta caaataccat
    59761 tggcaaaact ttcattatag ttgattgaac tgattgtacc catatattct tagtcatatt
    59821 atttacaaca ggagtaaatt tttcacttaa aaaatctata aatttattca taaacactct
    59881 ccccataaat attttatttg tttgatatta gttctagtgc ttcttccaaa gcctttgcac
    59941 catctagtct tccatatgca gttttagata tacatgctac tggaacgtta tattcattag
    60001 ccttttgttg aatttcttcc ttcatataat ctaaatgtgg tcctagtaat aaacaatcta
    60061 tttctgataa atacttatct atctctgact cacttctcgc ttttatatct gcttctatac
    60121 cttttttctt tgcactcttt ctcatactag ttgccataaa acctgtactt gctcctgaac
    60181 cacacgccaa aagcactctt atatttttca taataatacc tccaatattt ttatccatta
    60241 atttatttct taatgaactt tttattttat tatgtttata ttgtacttac caaataagtt
    60301 catttcacat aaatatattt cctaataata ggaaatcagt tactcttaat taaacatatt
    60361 aatatagtat aatgtatctt ataatacgta cattcaatta tataattatc atatcatcca
    60421 gattttattt taaaactatg cgagggaatc taatgaaaac atctaaaaaa gaactatttt
    60481 taaatttcat aaaaacacaa catgattgga tagattcatc tacattggct aattatctta
    60541 atgtctcaac gcgttcaatt agaaaatatg taaacgaaat taattccaat ggtgaattta
    60601 tattatcctc taaaaaagga tataaagtaa atctcaataa taattgtcaa accaaggttg
    60661 atagttcaga aaatatatca cctgataaca ggttaaattt aattttaaaa gaacttatag
    60721 ttaatagtaa tggaattaat atatttgatt taagtgaaga attgtttgtt agcccagcta
    60781 ctattgaagg agatatagtc aaagctaata aatttatagg aagttataat ttaaagataa
    60841 agcaatcgaa atttttattg aaactaattg gaaatgagtc tgcaaagcgc aaattaatga
    60901 gctctataat atttaaagaa acgggaagtg attttttaag cttatttgat gtacaaaaaa
    60961 tatatcaaga gtataatttg actaaactaa aagaaaatat aatatatata ttaaaaaaat
    61021 acaatttgtt tataaatgag tatgctataa acaacatact tcttcattta atgataacta
    61081 tagacagaat aaaaaagaat aactacatag aatctgtcga agtagtaaac tacatagata
    61141 ataataatga tataagtatt tcaagagata tatcaaattt tttagagtct gaatacaata
    61201 taactttaac tagtgcagaa ttatactact tagtatttca gttaacaaac aaaaccacag
    61261 tcttaaatta tcatgaaatg gatactaagt cattgccaaa ttatatagat gaacattttg
    61321 ttaaattaac taaaaaaata attaaaaatg tatatgactt atatcttata gatttatctg
    61381 atgaggaatt tgttgtaaaa tttactcttc atgtaaaaaa tttaatcagt agagccaaaa
    61441 ataatcaagt tttaagaaat caaatacctc aaaagttaaa agattcctac cctttgatat
    61501 atgatatatc tgtttatatt tgcaatcaga ttcaaacttt agaaaatgta gatatagacg
    61561 aagatgaaat atcttatata tctcttcatg taggttcatt ctttgataga caaaaattat
    61621 tagaagataa agttctatgt gcattaatta ctccaaatta ctatgattta caattcaaaa
    61681 tagtaagaga cctcgagaag agatttaatg aatccataga aattattcag attttttcag
    61741 atactcataa tcttgatttt gacaataagg tagacatggt tattactact ttaccaatta
    61801 acaatagatg ccctatacct tttgtttatg taaatcctta cctaaataga aaggattatg
    61861 ataatattca aagtaaattt actcaaatta aagatagaaa aaatatactt actgtacaaa
    61921 atcatttaga aatgtacttt agtgaatctt tgtttatgaa aaatatatat ttagatagtg
    61981 ctaaagatta tataaaattt atgggaaata ttctgtacga aaataaatat gtcaaaccca
    62041 attatataga tgatgttctt ataagagaaa aaatgtcttc aactgcattt aataacaatg
    62101 tagcaattcc tcatagcatg aaaatggatg ctttaaaaac tggagtatgt ttaattgtta
    62161 acgataaacc agttaaatgg ggtgaggaaa aagttcagat tatagctatg atacctataa
    62221 atgaaaaaga aaaagaaaaa ttcaattaca tatttgaaag ctttattgaa atattatctg
    62281 agtggaataa tgttaaagaa cttactaagg cagataacta tagtagtttt atgaatagaa
    62341 tagcttatct tattcaaaat atctaaatca attaatttat ttccaatata tgtttcttaa
    62401 gttattaaca taaaatagat aagctgtcac actaaaaagt ctaaattaat atgtgacagc
    62461 tttttaccta atataccttg ttttaatact acatattttt tgactgttgt atactagtta
    62521 taagattgaa tatttgtgtt gttgtagctg tcatattctc actagcagtt gctttatcca
    62581 ttgcttcttc tattgtcata gctctattta ctatagaaaa ataagcatct ataccctctt
    62641 cattacattt aactgcatct tctgttgtgg ctccagccaa acctattact tttacctcat
    62701 atttttttgc cagttttgca actcctattg gagccttgcc catagcagtt tgattgtcca
    62761 atctaccttc accagttatg acaaaatctg catcttttaa ctcttcctct aatttaattt
    62821 cttctaatat tatttttatt ccagattcta attttgaatt taaaaatgct aaaaaagcaa
    62881 aacctaatcc tcctgctgct cctgctcctt ctacattagc tacatcttta cttaagtaat
    62941 ttttaactac tttggaaaaa tttctaagcc cattatctaa ctcctcaatt atttctgatg
    63001 ttgcaccttt ttgagacccg tatatgtatg cagctccatt tttcccaaac agcggattat
    63061 ttacatcaca ggctatttta aacttacatt catctaattc ctttaatcta ttttctattt
    63121 ttatatgtct tatttcattt aaaacttttc cacctaatcc tactaacttg ttatttttat
    63181 cataaaactc aaaccctaag gcttgaagca tacctatccc agcatcatta gtagcacttc
    63241 cacctatccc aactataaaa tttctatagc ctttatttat tgcttccttt attatttccc
    63301 caacaccata agttgtagtg tataaaggat ttctaagttc agtcggaacc aatgttaatc
    63361 ctgatgcttg agctatttct attattgctg tacttgtatt ttttaataat ccatatgttg
    63421 catccacttt tttagctatt ggtccagtaa cttctatagt ctctttttta ccattcatcc
    63481 cttgaactaa agcatctact gtcccttcac caccatcagc aagtggcaat atctttactt
    63541 gcgcatcttc tttaaccttc aatatcccct tttttattgc atttcctgcc tctattgaag
    63601 ataagcttcc tttcaaagaa tctatagaaa ttaatatttt catacttatc tactcctttt
    63661 tattactcct tattttaaac atataatttt ataagcttaa tttatctttt attttatact
    63721 ctacatctct ctttgtatac aacttatacc attaatattc ttttatctta taaaaaggga
    63781 gtgtctcaaa ataaatttct tagttcatga gacactcttt tgtataaaat caaatatatg
    63841 tttattattt caacaatgat aaggaggatt atctctattt taagataatt cctttttagc
    63901 actatctaat catttttagc actatttaac cagtatagtt ttaacttggt tcattaagca
    63961 ctctacattt acagagttat tatctattga tatagattct aattcttttt catttaggtt
    64021 aatccattta gctgttttaa tatttttgtt aaatactatg ttagctgatt ttgtttcttc
    64081 tttagaatta taaaatctaa ctactaatgc ctcttctttt tcagcctttt ttacaacact
    64141 taacacaagg tccttattag tttccttaag taaactatat gaataatcta cttctatttc
    64201 tgattgattc aatttcatag cattatatgg cattttatta taagtttgta tttttgttaa
    64261 atactcttta gccatatttg caacatttgc ttctagtgta gatttttcat gagtaactat
    64321 tgctaagtct atttttatat ctcctatcat ttgagaatct ggagtaggca actttattcc
    64381 tgatggacga cctgggcgtc ttgccatttc ttctttacct aggaatccta cacttctaaa
    64441 taatgttata gctattgtgt caaatttttc ccctactatt tcaaactctc ttgtactgtt
    64501 tgtaagaaca gctactccat gctctttgtc agacaatcca acgaatgtta gcattggata
    64561 tatagaatct ggtctttcac tccattcttc ctgttgccaa acttccatag catcatcata
    64621 cacacttctc tttatatgtc caaactgatt atcagacaca gaaaactttg aagctatatt
    64681 tgttggtata taagttctaa ccctacaatc tcttgcttgg ttatttatgt tgaatactac
    64741 atctattata gctttatcat ttggaacatt tataactata tcaaagtcaa taaatgaatc
    64801 tgctctatta ttttttctag cttgtatatc ttttggtact tttaatctat aatttatctt
    64861 tatctcatta ttaaatctat ttttctttat agtggaattt gctactatat tatcgttaaa
    64921 tattaatttc tcatttggaa gtggtgaaaa atcatactca tctccttcat ctcctccatt
    64981 ttccatcaat aatacatttt caaaagtttt atttaatttt ttatcaaata tctttaatgt
    65041 cccgttttca ttaacttgaa tagtataaaa gtcattatct accatgtcac atacttcata
    65101 agctttttct aacatatgtt caacttcttt tatcatatac gccttatacc ccattgcagg
    65161 tattttatct ttaaagttta ttgtatatac cataaatgaa tcatagtttc cataatgaac
    65221 aatttgacgg tctattaatc ctgcatctat tacttcttta tgtaccactt caaaatccaa
    65281 cttattatta tctttatcaa atatttcaaa tgctttcatt ttagttataa cttgggtgct
    65341 cactatttca ttcctatcgt aaggcattaa gttaaatgct actaacttat ctaaagccat
    65401 ttcacaactc attgcatcaa ctattcttct tttgtaaaat gttattaatt ggtctacttt
    65461 ttcctcagct aagaaaaatc tattcattat ttcctggtga actttatctg aacaacaaca
    65521 tccaatgctg tcatgagcat gatttttcat tatttctttc caaattaact ctattaatcc
    65581 atgatgatat tcaaatccta gagaatatgc aatagaagct agtggctcca atatgttagt
    65641 tatctttgat tctattctag catttgctga ttttatatcc attcttgttg agaatatact
    65701 tctatgaacc ctcatatatt tcccatctaa aaattcccct tttattgtat ctatatcatc
    65761 atttttttct agctctttaa atatgttttc atatctactt aagaaaaatt ttctctctgg
    65821 ataacattct tttaatttat atataacttc aaatatattc ttttgaattg gcatttggtc
    65881 atgtccattt ggaagtatta tatggtcagt agttgcaccc ttatcaagaa ccggtaaata
    65941 tttatccatt cttgttctta gctcatcttc attcattggt agatattttc ctattgcata
    66001 acctaatgga agtatttgaa ccaaaacaga agacccatca tcactcttcc aattaaactc
    66061 tgttttatta gttccttttc tttcagaaca tcctctccaa aacattgagt attttatatc
    66121 aaacccattt agtatttgtg gcatttgagc actttgacca aatgaatctg gtaaatatcc
    66181 tattttcata tattctccaa attcatcaca atcttttatt ccatatagta aatttctaag
    66241 tatggattct ccaccaacta ccatttcatc agtttgagta taccaaggac ctattattag
    66301 ccttccttct tgaactaatt tttttattct ctccttacat tcaggcttaa ctgctaaata
    66361 atcttctaat atagcagttt gaccatccat cacataatat ggatagttat gattattttc
    66421 taacatatcc attatttctt ccatattatt tacaagtaat attctagatt cctcagttga
    66481 gaagtaccat tctctatccc aatgcatatg aggaactatg tgtacatttt ttttcattgc
    66541 ttatcctcca aaacttatct gataatattt tctgtctaat taaaaatcca ataaaaatac
    66601 tactgagttt acaaaatttt ttaatattta ttttatcact ataattaaac ctttgattta
    66661 aatatctaat aacgtatctt ttaatgtatc tttctttgat ttttttgttt cctagttatt
    66721 attaataata ttgctgatat tatagctcca agtactgccg caaagaacca tattgatgct
    66781 ataataaatc ctgacatact tccctctaaa agcgccaatg agaatatccc cgctccaggc
    66841 acttgaagac ctatattgaa gaatgctact atagacccag ttatggctga accagctacc
    66901 aatgatggta taacacggat tgggtcctct atcataaatg gtattgcacc ttcagttatt
    66961 ccagccaatc ctaatatcca agtttgcttt cctatttcct tttctgattc tgaaaataaa
    67021 tctctgccta aaacagtagc tattgtaact ccaaaagctg aaaccatctt aactgatgca
    67081 aatattgcat aaggtataaa atttccactt gctattgctc ctattgcaaa tgtataggct
    67141 gctttattta ttggtccacc taagtcaaat gaaaccatag ctcctattat tgcacctagt
    67201 agtattgcat ttactccagt catcccattt aaccaattta taagaccatt gttaagtgct
    67261 gctacaggct ttcctactac aaataacatc aataaaccta ctaccaaaga accaactact
    67321 ggatataccc aaaaacttac gaatccagct aatgtgcctt tggctggtat attcttcttt
    67381 aaaaatttta ctatatagcc agtaagtaaa cctcctaaca tacctccaag aaatccacta
    67441 cctattaaat cagctgctag acctgctgca aatcctggtc caagacctgg tttttcagct
    67501 agtgagtaag acatatatgc tgataatact ggaaccatca atgtacctaa catacctcca
    67561 gaaagctttc ttaattgcca taaccaagaa ccttcttggt tgtatagttc ttgtagacca
    67621 aatgcttgag atgctaatac tgcaaatgca agtatcatac ctcctgccac aataagtggt
    67681 attatatgag atactcctgt aagtattgct gattttacat cttttttcca tgatgatttt
    67741 tcacaatatg atatatcaga tgatttttct atataatcac ctttaccttg tttttgtgct
    67801 acttctaaag cttcgtatat tatttctttt gctcttttta gtggagctgc tactgacgtt
    67861 tttatgtttg gcaaatgttc aaatctttct gtatttttag gtgctacatc tgttgcatat
    67921 attattgcat ctgccctttt tattatatct ggtgtatgag ggtccaccat accattagct
    67981 ccttgctttt ctacatacac atccacaccg atttctttac cagctttaat taatgcttct
    68041 gctgacatat atgtatgtgc tatacctgca gggcatgctg ttattgctaa tataattttt
    68101 tttgattcat tttgaatcct aatctcttct tttatttgtt ctttcttttc ttttatatct
    68161 aagttattaa ataactcttt cttagttttt gaatttaaca acatattcat ataatcttca
    68221 tttgacagtc tagtaactaa ctcagaaagt atttgtatgt gtgtatttcc accttcattt
    68281 tctggtactg ctattaaaaa tattagctct actttattat ttgggtctac gctttcccaa
    68341 ttttctattg gtgtctctaa ggtcatagct gcaaatgaag cttctttaac tgacttagat
    68401 tttccatgag gaattgcaag ccctctttca aaacctgttg gagataaagt ttctctgtac
    68461 attacagctt ctaaatattc ctcataagat gttaacttgc cttcataata tagctttctt
    68521 gctaagaact ttattgcgtc ttcctttgtt tttatttttt gttttaaaaa aacaaggttt
    68581 tcatttgtga ttttcttaaa ttccaaaatt acgccctcct taaatcattt aatgctatga
    68641 atatagcata aaataaatta tgaaaatgtt tttttgaaat tatacacaca atttcttctt
    68701 aaaaaataaa gatttgtgta tttatacaca aatctctatc ttaaccagta ttgctctatt
    68761 attgctctca taatcatcat aattggaacc ttatctgata tattgtaccc atttacttgt
    68821 ttaattgttg aatagcaata taaacttata tctgcaattt gttgcaattg attttcacat
    68881 atatgtgtta gagctactac cttacaaccc ttattaactg ctgtctttgc tgcttctata
    68941 acttctttcg tttctccact taaactaagt gcaaaaaaca tatcttgttc acctaatttc
    69001 cctatatcat gaagtacttc atgtctttga ctatagtaag ttatattatc atgcccacct
    69061 ctaatttctt ttactaatat ctcacataaa ggaatgtttt gacctattcc ataaactata
    69121 atactcctag atttttgaat tatatctgct actttattta ttttttcata atctattagc
    69181 tctaatgtct tttttatatc tgattcaaaa ccattttttg gctctttatc ctcatttttt
    69241 aactcttctt ttaaattatt ttttagttga gagaaaccat catactccat ttttttacat
    69301 agcctaacta tggtatttgg gacagtaaaa aatttatctg ctaaagattg tattgataat
    69361 tttactattt cttctttgtt ttttctcata tattcaatta tcatgtcttc tgtatctgta
    69421 aatttatact catatttttt tgctctttca taaaattcca tagtttctcc tccatctatt
    69481 ttattattca taagtaaaat tcaaaaatat tagctaaaat tttcgttaat ataattataa
    69541 tttaatattt ttaatttatt aatgcatact actcttttta ttatacataa aaaatgtgta
    69601 cttcctatat tgatagagat gattcaagtt tttattttga tacatctcta tcaatatttt
    69661 tttagaaaat acacattttt ttcaaatact tatttttaat taaaacttta ggtaatctat
    69721 tctttatata taattattag acttgaaaat atctttaaaa tcaaccaatt caatattatt
    69781 tctttttaac cacattttaa cttccttatc acatagcatt gcatgttcat atactctctc
    69841 ttgaataaga gaagatgatt ttataagact ataatctata aatcctggat gagtaaccat
    69901 caatgttata tctttatcta aatttatata tttttcttca aataatttaa caaaagattt
    69961 atttaacttg taaaaatcat tctgaggata tttacttggc atgctaatac atgaatccaa
    70021 ataataggga caacttggta taccgtattc ttttgcagca tcacacattg ctgatattga
    70081 tacatcttct tctataccat gtatatcaat atactcaggc aatttactca tatacaactt
    70141 gtaagtttca atttgagcac aaacttcttc atatacttct tcataattaa aaacctcttt
    70201 acctgtcagt agttgcgttc ttcttatttt gctagaaaca aattttccac cttcatctaa
    70261 caaattcttt atcttaatat gttctttgca acaaggttct cctattacta aattaacatg
    70321 taaaccaaaa catacatcat cattttttac catttctata gcttgtcttg aaaaaggcat
    70381 attcaccatg attccagcac ttgtaacaat accgttctta taagaagata ttatccctag
    70441 tgtaacacct tctgaatatc ctatatcatc tgccctaact actagtttct tcattttatg
    70501 cgtctgcctg ctttctcaac tcatcaagtt gcatttccat ctcatccttt actttaacaa
    70561 catccgttcc tatgatgatt tgaactgatg tattactcaa tttaattacc cctttggctc
    70621 ctgttttttt aatattatca tcattcaaaa tagtagcatc cttcacttct aaacgtaatc
    70681 tcgtcataca attattaaga gtcactatat tttcataacc accacaattt ttaattatct
    70741 gtttagccat atatgaaaaa ttaccatgag aaagttttaa attcttttct ttttcactaa
    70801 ctttatcacc tatctctatc tcaacttcac gtcctggtgt ttgcacatta tcttttatta
    70861 ttatatattt aaatgttaca taatataata caaagaatac aactcctaca ggtataacta
    70921 accacgcttt atctccataa ctaaaactta agacatagtc aattatactt gctccattaa
    70981 atgaacccaa gcgaacaccc agtaaatata gtacaactcc acctagacca gaataaaaag
    71041 aatgaattat atataacttt ggagatgcaa ataaaaacga aaattctatt ggttcagtta
    71101 ctgttgccat aaaagaagtc aatgctccag cggtcattgc accttttact tcttgcttct
    71161 ttttatcttg tgctgtttta tatatagcat aagaaatagc aggtattgaa aacatcataa
    71221 ttatgtaaaa tcctgtccag aagaatcctg catttgggtc tcctgccata aatctaggaa
    71281 tttctcctct tataacttct cctgttgatg ttgtatattc acccatttca aataatatgt
    71341 aagcatttaa aacttgatgt aacccagttg gtattagtgc acggttacag aataaaaaca
    71401 agaatattcc tattgcacca gctcctccca accaaaaacc aaattgattc attgcagctt
    71461 gtggatatat ccataataaa ctaaatatat atgataaaat taaagcaacc actggtgata
    71521 gtgtaattac acatttttct cctgcaaaga agcttaaaaa tgctggaact ttaactttat
    71581 atgttttatt gtaagtccat gctatacaag ctccaacaat tatcccacca aatacacctg
    71641 catttaatgt atcattcaat aactctaaat ttgacttaaa tatcatatat gcaactacgg
    71701 ctgcaaccat tacacttgtc ttgtctttag actttgagta ggcactagct gctcctaata
    71761 aaaataagta gtccacattt gaaaatacta tattagatat attagatata gctggcacat
    71821 tgagcatatt tggaccaaat aataatccta atatacctgc tgctggcatt acagctattg
    71881 gcactagcat agtctttcct aaaagtgaca gttgttgcat cattttgttt aagaacctct
    71941 tcatatccaa tcccctttct atttcggttt aattttttgt gaaaacgatt tgttcacatt
    72001 ttatatttta aatattatat ttgtttaaac aaattgtcaa tattttttat tcattttatt
    72061 tttatcattt aatttaacat ataaatcctt ttaagtgtat tgctatatct agtctatttt
    72121 tttaattcat tttttttatt ttaaaaatat gtttaaccat gtatttgaaa caacccacaa
    72181 aataattcta ttttgtcctt tttatggttg atatgattct attttcacta tacatgtcta
    72241 aacacatttg atataatttg ttcatatcag ttcaataata ttactaaaga cctttaagga
    72301 gggatagggg tatatggcta aaaataaatt ttcagagata tatgaagtat tgaaagagga
    72361 aatacttgat ggtaaatata caagtaatat gatgctgcct actgaacttc aacttattga
    72421 aaggttttca tgtagcagaa acactgtacg tagagcaatt tctcaattaa acacagaagg
    72481 atatgttcaa agtataaaag gcaagggtgt tgtagtgtta gaaaatagtt gttctaatga
    72541 tttttttcta aatatgcaca atttcaaagg tgtagaatcg attgtagaag ataaaaaggt
    72601 taatactgct actagtgttc tccacttcag caaaatctta attgataata agttatctaa
    72661 aaagacaggt tttaaagttg gtagtgaagt atattacctt cacagactaa gatatattga
    72721 taacatacct aaaattctcg acattaacta ttttctatgt agtatagtta aagaccttga
    72781 tgtttctata gcacaaggct ctatttataa atatatagaa gagtgtctag gtacaaaaat
    72841 tgtttcatcc agaaagatat ttaaaattga aaaagctaca gagcttgagt taaaaacgct
    72901 acctctaaat gattataatt gtgttggtgt tattaaaaat agtgtatata ctgatgatgg
    72961 aaagcttttt gaatatactg aatcaaagca tacacctgaa acatttgtat tcatggatgt
    73021 tactcaaaga tattaaaaaa attatgttta attaaacata atttttttac gtttagacac
    73081 tttatcccat actaacctca ctattctata tacaattata tgtttataca aataattatt
    73141 tattgtatat tttagcttta atattagttt aacgcttgac aatttgttta aacatattat
    73201 aattaactta taaattacag gaggtatcaa gtatgaaaaa ttggtggaaa aaagcaactg
    73261 tctatcaaat atatccaaaa agtttcaaag atagcaacaa tgatggtata ggtgatataa
    73321 atggtattat agaaaaatta gattatctgt attctttagg tgttgattta ttatggttga
    73381 ctcctatgta cgtttctcct caaagagata atggatatga tatagaagat tattataata
    73441 tagacccaaa atatgggaca atgagtgact ttgaaaaact cttaaaagaa gctcataaaa
    73501 gagacataaa aataatgatg gatatggtcc taaaccatac atctactgaa cataaatggt
    73561 ttaaagaatc taaaaaaagc aaagacaatc catatcgtga ttattatttc tggaaagatg
    73621 ctaaacctga tggttctgtt cctaataact ggatatccag atttagtgga actgcttgga
    73681 aatatgatga aaccactaac caatattatt tacatttatt tgaagaaact caagctgatt
    73741 taaattggga aaatgaaaag gttcgtgaag aatgttacaa aatactagaa ttttgggctg
    73801 ataaaggtat tgatggtttt cgtttagatg tagtcaacct actctccaaa acacctggat
    73861 tacctgatga ccctataaca ggaccaaaag gagatggaag aactcactac gctgatggtc
    73921 ctcgtataca cgaatattta cataatatga atcaaaaagt tttcaaacct aaaaatatag
    73981 ttactgtagg tgaaatgtca tctactacac ctgaagagtg tatcaactat actagagaaa
    74041 atcgagaaga actatctatg gtttttagct tccatcatat gaaaacagat tataaaggag
    74101 gcgcaaaatg gactaatgaa atgttctctc tggataaatt aaaaaaagca caatctgact
    74161 ttcaatataa aatgtatgaa ggaaaaggat ggaatgctct attttactct aatcacgacc
    74221 aacctagagc tttatctaga tttggagatg atagattttt tcgtcaagaa agtgctaaga
    74281 tgttagccat aacattattt ggtctacagg gtactacata catatatcaa ggtgaagaaa
    74341 taggtatgac aaatgcctac tttactaaaa tagatgaata tgatgatgct gaaagtaaga
    74401 atgcatacta tcatatgatt aaatctggta ttgatgaaaa ggaggcattg cttatacttc
    74461 aacaaaaatc cagagataat gcccgtactc ctatgcaatg ggataatact atttataagg
    74521 ggttttctaa tcataaaccg tggttaaaag ttaataatga caatattagt gtagaaaatg
    74581 agcttaatga ttctcgttca gtattttata cttatcaaag attaatcaaa tatcgtaaac
    74641 aatatgatat ttttacagaa ggtacttata gattgttaga tgaaaatcat aaaaatctat
    74701 ttgtttatga aagagagtat aaaaaccaaa atcttcttgt tataagtaat tttactcatg
    74761 ataatgtagt atataaatta cctgaaactt atttgaataa attaaactac acaatacttg
    74821 aaaccaatta cactagagat ataattgaaa ataaaatgga aataaaacct tacgaaagta
    74881 taatgatata ttataaataa agttatttat gtaaaaatcg gtataacacc ctggtgttat
    74941 accaatttta ctaaattcaa agtaatattt atagaatatc tatagattac aataattatt
    75001 tgacttctac atcattatat ttctttgaat atactttagt catatagaaa tatataggaa
    75061 ctacaattat catcccacct aatccccaaa ctatcttcat aggttcatca atacctgctt
    75121 ttatcagtaa taatatactt ataataactg caaatattgg tataattgct cctccaggta
    75181 ttctaaaatt tacatcttta ccagcatact tctttctcaa tattagtaca gctaaacatg
    75241 taggaatata ttgaataaat ctagatacaa cacttatttg agataatgtt gtgaatgaac
    75301 ccgaccatgc tattagtaaa gttcctatga cagatactat aattgctata taaggagatc
    75361 catttttatt agtttttctt atagacttag gcattaatcc ttgttcaacc aaagcagcag
    75421 cagaccttgg tgtaaatatg gatgatgcaa tatttatacc tccaacagat actatagttc
    75481 ctattgtaat tatataccca cctataggac ctaacatctt aatggcagca tctgcaacag
    75541 gagtagctga ccctgctaag ccattaccca acacccctat acttattccc agtataagca
    75601 tatatattac tgatactaca aacattacca ttaccaatgc tttaggtaca tttttcttag
    75661 ggttctccat atcttttgct gcaacagcta aagattcaaa tcctgtaaaa gcataaaata
    75721 aagttataga tactgctaca aaagctgatg acgcactttg acctttttgt attattacaa
    75781 atggggtaaa attagaaccc tttataaaga ataatcctac agctataaat aaaactattg
    75841 gtaataattt tcctatagtc atgatattat ttaagtgctt agattgtttc attcccataa
    75901 aatttataat cccaagccct acaactaata taccaattat tatattttta ataagtggtt
    75961 ctgctacttg tggccataca gatgatagtg ttacagcaaa gaaatttgcc atagtagccc
    76021 aagcaatcat actaactatc cacttcataa atccaacttc aaatccaaca aaatctccaa
    76081 atgcctcttt tgcataaaga tagggccctc catcagtatc aaaccaacta cctgcttcag
    76141 caaaacataa agcaatagaa acagctaaaa gcatacaaaa aactaatact aatatacttg
    76201 ctggacctat atctgtataa gcatcaccag gtaacccgaa tatacctgac cctattattg
    76261 cattgattcc taatagtaca atactccaaa aacctaactt aatgcctttt tccattgtta
    76321 ttccccccaa agccaactta atatatttat attttttatt tagatgcttc tttaactatt
    76381 gccataaata tttttttcat attatcataa tctctagtca tcatttctgg atgccattgt
    76441 atccctatta caaactcact tccttccttt tctatagctt caattaaacc gtctttagat
    76501 gtagctgaaa caatatatcc cggtgctact ttgttgacaa ctaagtgatg aaaactatta
    76561 actaaaactt ctttttctcc tagtatttca tataattttg tcccctcctt tatctgtact
    76621 gtatgtgtag gtacattaga tagatgttgc tgattgtgtt taatataagc accttcaatt
    76681 aaagataaat cttgatacaa actacctcct tcagttacat ttataatttg ttctcctcta
    76741 catataccta aaactggttt tttcatatct aaagcatgtt ttaataattt catatcaaaa
    76801 ctatctctct ttggtgatat tgcccccaac ttattatgag gttcttcttt ccatatgagt
    76861 ggatttacat cttgtccccc agatagtata agcgcatcta tattagatac ctgctccttt
    76921 ataatctcat catcatatac aatcggtaca atatatggta tagctttaca cataactact
    76981 gattgtatat aatcattatt tacataagcc ctttcatagc caggaaacat tcctccttca
    77041 tcaattagta aattacctga tattcctatt attggatatt tctttttagc caatttcttc
    77101 accccttaac ttatttgtga acaataaaaa atgctacttc tcttaaagag caagtagcat
    77161 accaagattt tatttatttg aacattataa tttattttag aaatactttt tttgaatacg
    77221 agtaatataa ataactttat ttacttatat tttattttaa tcctgtttag tttgactttt
    77281 ttaaattgtt ttaagtacaa ctaataggta aaataggcat ttagattttc ctttttatca
    77341 acctattaaa tactgtttaa tatatttttt ccccttctat ttaattcact tccctttcta
    77401 ccagattcac atattatcaa atccagctct tttaacatat taagtattcc tcttacctca
    77461 ccttctgtta tattgtagcc taattcattt attgaattaa caataccatt tctacctata
    77521 tttttattaa gattattggc attttttaaa cactccatta ctaactttac tttctctata
    77581 gatgttctat cctttaatat gcttatttct ttactaaaat cttcagttat atttaataag
    77641 ttatgaggta aatcatttat taaaataaca tcctcagaac tcataatgtt aatatacata
    77701 gcagtatttt ttaattctct tatattacct ggccattcat atgcattaat aatgtcttga
    77761 acatcttgac taattgctct cttccttttc ataaaatgct ttaacataac ttctatatct
    77821 tcttttcgct ctcttaaagg tggtatattt atgggcaata catttatcct atagtataaa
    77881 tctgctctaa atctatctcc ttttatcatt tctaataaat ttttatttgt agccgcaatt
    77941 actctaacat ctatatctat tacattttct cctccaaccc tcattacttg attctcttgt
    78001 aatactctaa gtaatttgct ttgtaagtat ataggcatgt ctcctatttc atccaaaaat
    78061 atagttccat tgttagcctg ttcaaataat ccttttttac ctccttttaa agctcctgta
    78121 aaagcacctt cttcatatcc aaaaagttca ctttcaagta aattttctgg catagctgca
    78181 cagtttattg ctataaatgg ctgactatgt cttggtgatg cattatgaat agactgagcc
    78241 atgagttctt ttcctgttcc actttctccc gttataagaa ttgtataatc agattcagct
    78301 attttcatac ctaatttctt agttctttcc atcttcgttg aaactgtttt tatatcatca
    78361 aaagtatatc tagcaacttg tcccttttct ctaagcttct ttgataggtt ttgctccaat
    78421 tttcttatgt aagttatttc ttgaatacaa aaataatatc cagtaaccct tccaaaactc
    78481 tctatattat acttatttac gtttaagtac ttattattaa attttataac ttcatcatgt
    78541 gccttactca aactaaaaat ctttttaata ttctcattct ctaattcatc tatatttttc
    78601 cctataatat tactttgaat atctagtata tcccttaaac tattattaca aataattatg
    78661 tttcccttat ctgataccat tgccatacct aagtttgata aatttattat ggaatttagt
    78721 tcatctgctt ttatagtaag ttctttgtat ttagtattta ttcctgaata taaactaatt
    78781 atttcatctg tatacttaat tagcctctca gtaatttctt tatcatccag tttgagtttt
    78841 gctattattt gaataaacgt tgaactatca atatacctat ggcctaaatc aataacttct
    78901 tctatatatt ttggaactaa acttgactct cctggcgtta tagctatctt aatatttcta
    78961 tattcttcat tgggattgta tggtataaaa ttcaaatgat ttattcctat attgtataaa
    79021 ttagatattg tttccaatac agtatgctta ttatcgttta ctactaatac atctattcct
    79081 tctggcaatg aaaataactt atatatatcc ttttgcttta tgctcctatt tatagttatt
    79141 atctttgaga catcttccac atattttttt atttttaata ctctatcatc tatcattacc
    79201 aatattatgt catcttttat taattccttc tctgttattt tatttaaata ataatttttt
    79261 atcattactt tatctttaaa gatcatttct agatttttat ttaagaaaca ttctaattta
    79321 gacaacccat cagttactac tgctattgtt ttcatttgat tactcctttt aaaatatact
    79381 ctactctttt ataatataca tttgattttc actttaataa cacaaaaaat tgtacattta
    79441 gtatactaac atattccttt attagtttta tgtccataaa tatcatagtt gcaatatcta
    79501 tcatatttct taaacttcta taaagcaaaa attgtgccaa attaataatt ttcttaattt
    79561 tattctaaag ttcctcaata gtatttacag acttagcact tatagcttat aagtctttat
    79621 attattaatc tatttttata ggttaattgt acaaatcata tatcactttt acctattaaa
    79681 tgcattataa aaaattgtat ttataaacac tatttactac tcttctaagt acaaacagta
    79741 tctacatact ataacctttc accattagat tctattactt gtttatacca gtcaaaactc
    79801 tttttcttaa tcctagacaa gtctccactt ccatcatcat acttatccac gtatataaac
    79861 ccatatctct tggccatctc accagtagat gcacttacta aatctataca tccccatgga
    79921 gtatatccaa ataaatcaac gccatcttct acagcttcct tcatttgctc tatatgtgct
    79981 tttaaatact ctatacgata gtcatcattt atcactccat tagattcttt tttatcataa
    80041 gctcctaaac cattttcaac taccatcata ggtattctat atctatcata aatttcattt
    80101 agtgcatatc taagcccttc agggtctatt tgccatcccc attcactaga cttaagatat
    80161 ggatttttca ctccacctaa tatgttgcca cttgtattat cttctttaga atcactactt
    80221 acacatgtag acatataata actaaatgta taaaaatcta cacaaccttc ttttaaaatt
    80281 tctaaatctc ctttttccat ttttatttca atattatttt ctccaaaata tctattcata
    80341 taagttggat attcgccacg cacttgtaca tctccacaga aataattcat tactctacta
    80401 tctctttgag ttttaactgc atcatctgga ttacaagtat aaggatacat tgttgcaaat
    80461 atttgcatac atccaacttg ataatttgaa tctatttcat gagctaactt aacagcctta
    80521 gcacttgcta caaattgatg atgtaaccct tgaaaacgaa gttgaggtat atctacttgg
    80581 tttataaaat ctgtagtccc ttcatttaat attccttgtg ataagtagcc tcccataggc
    80641 attgtagctg aatttatttc attaaatgtc agccaatatt ttacttttcc tttatatctt
    80701 ttaaatattg tttcacagta attcatatac aagtctatta catctcttga aacccatcca
    80761 ttgtatttct ctgttattgc aaatggtatt tcatagtgag atattgttat taatggttct
    80821 atattatatt ttaaacattc atctatcaca ttttcataaa atttaagtcc tgcttcattt
    80881 ggttctttct ccattccagt tggaaatatt ctagtccatg ctattgaaaa tctaaatacc
    80941 ttaaatccca tttctgcaaa taaagctata tcttctttgt atctgtgata aaaatctatt
    81001 gcttcatgac ttggataaaa tgttcctttt tctataactc tcgttattct tttacttact
    81061 ttttgagaac ctccagtaca catatctgaa caagaaggac ctttcccatc taaattccat
    81121 gctccttcac attgatttgc tgctgttgct ccaccccata aaaaatcttt tctaagtgcc
    81181 ataattctac ctccaataat ttatttatag taactttatt ttaaaataaa aatacatata
    81241 tataattctt aattaataga actctctttt acgctaaaac agttatcaat ttctgactat
    81301 tatttacatg cttttgtgta ttttctacaa tatccacata atcagaataa ttagtaacaa
    81361 ctactggtgt ttctaagcaa tatccttctt ttgaaatact ttctatgtca aaagttatta
    81421 atgtctgacc ttttttaatc ttatcccctt gattaacaaa agatttgaaa tatttacctt
    81481 ccaactgaat agtatttaac cctatatgta tcaatagttc acaaccatta tcagatataa
    81541 ttcctattgc atgttttgtt ggaaataaag tcattacagt cccatcaaat ggtgccacta
    81601 cttttccttc tttaggtgtt attgctacac cttttcccaa tatacctgtt gaaaacgctg
    81661 catcttgtat ctgctccaaa gcctttactt caccttttat tgggctatat actacttctc
    81721 ttttgttttt ttctataacg ccttgcccat tatcatcttt agaaatttct actatagcat
    81781 catctttcca aaaaaataat gttaaaacaa atcctactac aatagctact attattgcta
    81841 ttatagttgc ataaacacct ttcatatctc cagttgttgg atttatataa ttaggtatac
    81901 caaatattcc aagtccaccc attacataac tttttacatt cattatcccc attacagctc
    81961 ctgccacagc accacctaca caactatata tgaatggtgt ttttcttggt aaagttattc
    82021 catatattgc aggctctgtt acaccacata tccctgaaat aactgcaggt atacacagct
    82081 cttttatctt cttatctttt aatttaaagt acattgctgc tactactgct gtttgtgcaa
    82141 aagatggtac aaatgctccc actaatattg tgtcaaaccc catagtcata aggtttgaca
    82201 tagctattgg tactaatccc caatgtagac caaatattac aagcacttgc cacaataaac
    82261 cagttaatgc accacataaa attggtgaaa agttaaataa agctaaaaat ccatttccaa
    82321 ctatattaga agcataggta gctataggcc ctataaccat aaatcccaat ggtaaagaaa
    82381 ctaataaaac tgccattggt acaaagaaat tctttactac atctggtatt attttagcaa
    82441 acactttctc caacttagct actaataata ctattaaaat tactggtact actgttgaag
    82501 tgtagttcat tgctattact ggtaatccta agaaagttat atatactggt gattcaaata
    82561 ttgttccagt aaatagattg tataaaggtt gacctgtaga tgctagagta tctaattgaa
    82621 tacctgaata gcataaaact gcacctataa gcattccaat aaatggtttt aatttgaatt
    82681 tcttagcagc tgtatatcca agaattattg gcatatactg gaacattgca tctccaattg
    82741 catttaacat aatatatgca ccatcagttt ctccatacaa acccaatgct gtaaatactg
    82801 cattaaatcc ttttatcata ccagcagcac acagaactcc taatattggt tgaaaaactc
    82861 ctgatattat gtctataaac ttattaagta atccttttgg cgcatctgag tctgaattat
    82921 ctattgtatc tcctcctaat ccagccaaat cgcacacaac ttcataaaca tctggaacat
    82981 gattaccaat aactacttgg tattgacctg cacttttcat tacagtaact ataccatcca
    83041 ttttttttag cacatcatca tttgctattg actcatcttt taatttaaaa cgtagcctcg
    83101 ttatacagtg agataaactg ctaatattat cctttcctcc tacattcgca atgatttctt
    83161 ttgatagttg ttcatacttt ctcatttttt ctcctccatt ttctttttga aatatgaagg
    83221 tttggccaac ttaatgtcac cacccaatat atataaacct aattattagg atttatatct
    83281 gacttaatac ttttacttac cactctttca acgtgaatag ttaagtataa tttttcctca
    83341 tctgttaaat cgtagttgta ttttttatgt ataaattcat ccaacttttc tatgaattta
    83401 taagcatttt tatatttaac ttttattaca tttaataaat catcttcatt attttcatgt
    83461 aaattattac taacaattcg ttctgcaaaa tactttaagt gagtaataaa tctatgataa
    83521 taaactgaat cttcatcaaa tactattctg taatggtatt taaccatatt tgaaatttct
    83581 tgtattattt gtgtaatctc atatatagtt tttatacttt gatccatttg tgcattaact
    83641 atatgcagtg ctataaatcc agcttcatct tctgatagtc taatttcaaa ttttttttct
    83701 atataatcca atgcctctaa ccctatttta aattcactct tataaaatct ttttatatcc
    83761 caaagtaata cattttttac acttactcct tcacgagctc tttctattgc agtatacata
    83821 tggtctgtta aagaaatata aatactatca tttaatcttt tccctagttt ttctttagca
    83881 tataaaatta tttcatctga taattccata tatcttatag gaatatctgc tattagttct
    83941 ttaaatttat cagatatatt tgggtctgaa agtttgaata tcttatcaat tttatccttt
    84001 gatatatgct ctcctgtacg ttttttataa gctaaacctc tccccataac tactatttcc
    84061 ttatgatttt catcagttgt aataattaca ttattattga gtattttttc aataatcatt
    84121 gtgatgcccc ctttattagc attaagttaa aataaatctt ttttaattat ttagaatatt
    84181 taaaatgtaa tttattacat aaaaaaaaac ctatttatta cacattaaat agactcccat
    84241 gagtcctgag taataaatag gtttagcttg tatttaaaca atcactatcc gtttgtattt
    84301 tattttaatt attatttatt atatgttagc aaatttattt tttagtgtca actttttctc
    84361 aatattttaa ttttaaataa attatataaa ttgaatcttc aaagtaatat ttttatcaat
    84421 aaacaaaata aaaaaggtat tactttcttt aagtaatacc catttatttt taatttaagt
    84481 ggtttttctt aatctcatca agtagtccat cttctaaata aatttctaat gcacatccta
    84541 ccattgcctt tactgctttg tgaagtttat cataagcttc ctcagaattt gcataattta
    84601 gaaattcttt ttcatgaaca tataccattg gacttatatc taaggctatt tctgtataca
    84661 tagtagggca aacttgactt acattaccta tatctgtaga acctactgga ccatctttac
    84721 cttctaatat atctgttata cctgcctcaa tcaaattatt ctttgttatc ttttgaagta
    84781 ctttgttatt tattatgttg tcaaaagaat tttcaaagta tctataagaa agcttagctc
    84841 ctgtcattaa ctctgcacct tttgcacagt ttataacttt tttagttact tcatctaaat
    84901 aacttctttc agcagctctt acgaaaaact tacaggctgc tttttctgga actatatttg
    84961 gagcctctcc tccatttgaa actataccat gtattctaac atctgatttt acatgttgtc
    85021 ttagtgcatt tatcccagca aaagtaagtt gtactgcatc tagtgcatta actcccatat
    85081 gagggtgact agctgcatgt gctgataccc cttcaaaact aaactctaat gaatctatcg
    85141 ccaaagcctt acagtttata ttattaaaag cttctatatg catttgataa cttacatcaa
    85201 catcatcaaa agctcctgcc ttaactaaat cacattttcc tcctgttgtt tcttcagctg
    85261 gtgttcctat tagtacaatt tttcctttaa aattttcttt taacttactt aatactatac
    85321 aagctcctag tgtagatgct gcaatccagt tatgtccaca agcatgagct ggttctttat
    85381 tttctccata tccaggaagt gcatcatact cagctaaaaa tgctatggta ggtccatcat
    85441 tatctcctaa ttcagctcta aaagcagtct ccatattaca atatggataa actgtatcaa
    85501 atccatattc cttcattttt tctactaagt attttgatga tatgtattct tcttccccta
    85561 attcaggatt gttaaatata aaattacaaa cttcttcaat ttcttttcca agtccattct
    85621 ctatctcata agctctcttc tttatactct ctatcataat ttacctccta ctagaatcct
    85681 agatataatc ctattgtcaa aaatgccatt acaagaattg ttaatactac cattaaagga
    85741 attacgaatc taacccactt tgaccaagga atattggcta ctgctagtgc tcccattaaa
    85801 acacctgatg taggtgttat caagttagtt acacctatac caaattgata agctgtaact
    85861 atcatttgtc ttgatacatc tactaagtcg ccaagtggtg caagtacagg tattgtaagt
    85921 gatgcaagcc ctgatgctga tggtattaaa aatgctatta atccttctat taagaaagtt
    85981 aaatttataa atatagtttt tggtaatcca tttaataaat ttgctgcaga atttaaaatt
    86041 gtatctatta taaatccatt ttctgctatt attacgattc cacgtgcaaa tgctatacac
    86101 aatcctgctg taattaaatc tcctgctcca cttataaatg aattaactat ctcatcttgt
    86161 ttaagccctg atgctattcc tgatattata cctatagctg taaatatcat tgcaatttca
    86221 gttatgtacc attctagtct taaaactcca tatatcataa tcgccatacc tattgtgaaa
    86281 atggctatta ccatggcttc tctttttgta aattccttta tatttgtatc actattaacc
    86341 attaattctt gatttagtga tatatcatgt actaaagatt ttttagggtc ttttttaact
    86401 ttattggcat acatcataac aaatcctata gatatagcca tatatattat aaacataaca
    86461 actctaaact ctattccaga acctggtact atttgtgata atgcttgtgc tattcctaca
    86521 gagaaaggat tcgtagtagc tgctccaaat ccagctgttg ctcctataaa tactgtggcc
    86581 actgctgtca atgaatcata tcccatactg gtcataagtg gaataaatat catataaaaa
    86641 ggtagtgtct cttcactcat tccaaacgtc gtcccaccta gtccaaatag aatcattgaa
    86701 atcggtatta ttaaaaattg aaacttcttc attttattta cagtatgagc tataacagct
    86761 tctatagctc ctgttttatt aactatccca aaagctcctc caactattaa aacaaatcca
    86821 actacttcag ctgcatctat aaacccgttt ataggtgctg taaatacatc agtaattcct
    86881 tgtggatttg atggtgcttt ttcataagtt ccagctacaa caactgacct tccgtctata
    86941 tctactcttt caaaatttcc acttggcact atccaagtaa gaattgccat taacactatt
    87001 agcaaaaata ttattgtaag tgtctgtggc atagtaaact ttttcttttt taaactgctc
    87061 atttttaatc tccccacttt ttaaattaaa tattttatta ttgcatccct ttatcctatt
    87121 ttgtatagat gtaaaaaagc tcaacatgga tacatgttga gctaaatgtg ctaaatacaa
    87181 catacctgca tcttcccttt atcttgttta agatagctct ccatcaaaat tcgggataat
    87241 tttgatgaca gtactgtacc tattaaatac agtcccagca ctagcttcgg acactagcac
    87301 ttcggcactt actcctttta tattgcctca ttggtttcca acctcttcaa tattaatctt
    87361 agtaaatgca acctctacct caatctgttt gttagatgag gtaattctta ttaattttta
    87421 ttaattcaaa gtaattgtag cataatatgt cgagattgta aatattttca gtataataat
    87481 tcttacttta tgatttcatt ccatttttca caaataattt tttctccata taatttaaat
    87541 actgtagtat attttaaata cacacaaact ttccacaaat tttaaattat tataatacct
    87601 ttataataaa aaataaaagc tatgtaaact tatcaattta catagcttta tatacattaa
    87661 tctactccaa gtacagcttt aagctttgat gctattgtaa taactcgtgg accaaatata
    87721 acttgaactg agtttttctt tttaacaact ccacttgcac ccaattcatt tacccagaag
    87781 ccatcttcat agaatccatc aattgaattt agctctaccc taagtctagt tgcacagttt
    87841 gtaacatttt ttatattatt acttcctcct aaaccttcta ttatagaatg tacaagcttt
    87901 gtatctttat catctacttc ctcttctact gcattgttgt atgctgtttt accagcatct
    87961 acagattgtc tttctctata ttctttctta ctataaagct taacttcttc tgagcttctt
    88021 cctggtgttt ttatatcaaa cttcttgatt gcccatgtaa atattatata agtaactata
    88081 aaaaatattg gtatcaaaaa taataatggt aacgcatcca ctttttgtgg ttgtaataaa
    88141 ttaggaaaca tatttctaaa tgattctccc attatagaaa cattaaacat ttctgtaaat
    88201 acatacgtca atcctgccag tggtacatat gctacaaaat ataataatgg tgcaacaaat
    88261 aggaatgtat actctattgg ttccgttacc cctaccaaca tggctgttac tattgctggt
    88321 atcaatatac ttattgcttt tttcttatta gcattatcag ccaacttata catagctaaa
    88381 gctgctgctg gtaatattgc aaaatgtatt aataaacgac ctgttgtgaa gttacgagtt
    88441 atataagata gtgtatctgg gtctcccatt tgagctaatc ttatattatt aacaccctcg
    88501 taaattgctc cacctacttc cattgttcca cctactcttg tatattctat agggaatgca
    88561 attaagtgat gtataccaaa tggtaataat gctttatcca ttgctccaaa agtaaatgtt
    88621 cctaataatc cactagaacc tatccaatta ccaagtttag ataatgccaa ccctactggt
    88681 ggccatataa agtacattgc tgtacctaat actattgatg ctataaacat cataatcatt
    88741 gaaaatcttg gacctgagaa aaaagataat gcactaggaa gttctatgtc aacaaatttg
    88801 ttatgtactg cactagctac aaatccagct attatagctc caaatatact acaatcatat
    88861 gaaaagattc ctaagaaaga accatataaa gaacttcgac tatatgcttc tgcctctcct
    88921 aatccagatg ccataaacgc ttctgctgta actgtatctg aatttatacc atttgctgct
    88981 aacaatgtac ttataactgt gtgcattcct ataaataaaa caattcctcc taatgcaccc
    89041 catccttttt cctttttaga taatccaaag gctatacctg taacaaagaa tattggtaag
    89101 tatctcatta ccataaatcc taaatcgttt attactttaa agaatacatt tataaatgac
    89161 ccttctttta ttagtccgct aagccctaat gcagaaacgt tttccatatt tgcaaaagct
    89221 gaccctaatc ctataaatac tcctgctaca acaagtaata taacaggtat catcattgct
    89281 ccagaaagta cttgtaattt atccttcata gtattatttc ctccattttt attgaaatgc
    89341 caggctatat aatgcatata tatatacttc tattgctttg tataatgtat ctatacttat
    89401 attttcattt gcctgatgtg aatttggatt atccccctct attgtgggtc caaatgcaac
    89461 tccatttttt aacactcttg cataagatgc agctcctttt gtaaaaagtt cagcttcttt
    89521 tccaaaacct tgtttatatg catttgataa tttatttatt aattcactat ctggttttac
    89581 atacagtaat tttaaatcct tatatatatc aactattaaa ttttcttttt ttccaatttc
    89641 attaattcta ttagttataa actcccaact tataccctta ggatatctaa agtctatttt
    89701 catattcaat tcatttttct ctaagaagat actcattata catattgtag aaacccccat
    89761 atctacatct tctttatata tccctaattt ttttccatga ttatcatctg taaagtatga
    89821 atttaaaata tcccttatta taacgccttt atcatttagt tttttaattt tctctaaatc
    89881 ttttgctaaa ctaaatgcac agttatatga cctgtgtgga tttctcgata aagccctttc
    89941 tcctgtatat cttactaata ctttaccttc ttctagttct tctatctctg tataataagc
    90001 taatgattct actaaatctt tcttatcatt agttttaaaa acagcctcaa ttttgttaca
    90061 tacaaatcca tcttctttgt ttgactttat atcaactaaa ttgtgatttc taaatttatc
    90121 tttatctatt ttctttctta gattgaagta taaaatacct ttttctccat ttactattgg
    90181 gaagtttcca tctggagaaa atgcaaattt tggctgttca ttgacactaa agtaatgctc
    90241 catacattcc caagtcgtct cttcagctcc acccactatc aatctaatct ttctcttcgg
    90301 cttttcatta agttctctta agaaaagtaa tgcatataaa atccctatca aaggtccttt
    90361 gttgtcatta actcctctac cataaagata gttatctttt tgacatactt taaaaggttt
    90421 actcttccaa agttctttat tatatattgg caccacatct atatgattaa gcacccctac
    90481 tacttcttct ccttctccat attctatatg aattgcatat ccatcaaagt cttttacaac
    90541 aaaatctttg tcttttgcta tttgaataag cttatcgaag gcatttctta tttctatccc
    90601 aaatggttga tttatatctg ttgtactttc atctctaatt gaaggtattt caactaaact
    90661 tctaatatca tttatgatat tttcttgatt ggattttaaa taatcaataa ttagttcttt
    90721 gtttactatc atcttaatta tttatcaccc ctttatatta attttacaaa gcatttcagt
    90781 tcatatctac attataaatt ttgaatatta ttttttcaat atttcaaata cttctctaag
    90841 ttaccataat gatacggtaa acaatcaaca gattatgaca aaatcatact atacctatta
    90901 ctaatatttt aacttatcta ttacgtcttt tttaatgtaa gtttattcca aaaatacata
    90961 aaaaaagatg tagccttagc tacatcttct tatatctatt caacttccat tattatgcta
    91021 ttaatatcta catttccagg ttctatccta tcttttactg ttctcttaac agaatcagca
    91081 tcatccatta taactacagg agttattata tttaaatcat ttgacgttat aaaatctaaa
    91141 tctacttcca ttattaaatc tttagctttt accttatctc ctgcctttac cttaacatca
    91201 aacggctttc cttctagtga cattgtctct aaacctacat gtattaatat atttgtatta
    91261 tcattactct taatcattat tgcatgcttt gtatcaaata cattgactat ttcaccatca
    91321 acaggagaat ataacttacc ttcacttggt attattgcta ctccatctcc catcatcttt
    91381 tgggcaaaaa ctgcatctgg aacatcttct aagttcacta aatttccctt aaaagggcta
    91441 tatattttct caatcttatt ttcttttttc ttaaatatat taaacataac acactctcca
    91501 cattataaaa ttttatgata atatttttct taaagctttt gctacaccat catttacatt
    91561 agtatcagtt acaaaatctg ccatagattt tacttcatct gtagcatttc ccatagcaat
    91621 accaagacct gcaaatttaa tcatggatat atcattttca ttatcaccta tacaaataac
    91681 ttcttcgcta tctataccta atatatcaca aaatttttta actgcaatac cttttgaagt
    91741 acctttgctc ataacttcaa aatttatctt tccagaactt actacttcta aatcttcttg
    91801 ttttttaaat tcttcctttg cttctctcaa agaatctacg ttttctgaga aaagtataca
    91861 ttttaaaatt tcattatcag ctttttctaa taaagtttca caacttgcat tttctattat
    91921 ttcaattctg tcttcttctt tatttttact atttattaat ctatatggat gttcttcacc
    91981 tatttcattg ttggatataa ctattttaca gcctttaaaa tgtttgttta aattatactt
    92041 ttcacctatt gtatagattt tctttagagt ttctttgctc aaaaccttct tatactcata
    92101 tcccagtaat ttaaaatatg tcccattagt tgatataata tatatatcat cccctaaaac
    92161 acttgtaaaa tatttcatag cattataagg tcttcccgta actaaggcta ccttgatacc
    92221 cttttccatg acttctttta gtgctttaat attttcttct gatacttcaa atcctttacc
    92281 catcaaagta ccatccatat cagtacaaat taatttatat cgcatttgta tcacatccta
    92341 gtaagatttt tctaatattt caacaaggtc ttctttcttt ccaaaaggta aaaatcctaa
    92401 aactggacag cttgttattt gttctaattg ttcctttgtt acattaaact cagacatttt
    92461 tgtcttaagt cccactctct ttaaaaaact ttctatttca tttcctaaag ttttagctgc
    92521 ttcatcatct tccacttttt ctaattcttg gtttagcatt ctcgctactt tggcaaattt
    92581 ctctatatta tccttataga acttttctgc aaattttggg aacactatag ccaaagcctc
    92641 accatgagga atatgtgtaa ctcctcctat tatttcactt agtggatgtg gtgctgctgc
    92701 tccagcattt gccagtgaac ttcctcctaa tgtatctgct actgctaact ttgttctgta
    92761 ttctatatta tttttatctt ccattacttt aggtagatag ttaatgacta attccataga
    92821 tttttcagac attatctctg taaaatcatt agcatttgga tttatataac tttcaaatgc
    92881 atgggtaaaa gcatcaaatg ctgttgatgc agtaattctc tctggcagag ttaacataag
    92941 ctctgggtca actatacatt cttttgagaa acaattttga tgaaatattg tatttttctc
    93001 gcttcctctc gatattactg ctgcttgtgt aacttggctt cctgttccag aagtagttga
    93061 tacagctatt aacggtaatt ctttttcact taccttatcg tatattttaa atggatttgt
    93121 atatgtacta aacatataat cccaatctat cttttctaaa ccaaaagtca atgctaatac
    93181 ttttgcagta tctatacttg aacctcctcc aacagctaaa acaacatcta cagattcttt
    93241 tttagctaat tcaaaccctt catttattaa ttctacagtt gggtttggct ctactctatc
    93301 aaagtgtaca acttctatac ctttttctat taaattcaat gtaactcttt tatataactt
    93361 gtctaatggc tctacatttg gagtagtaac taacaaacat ttctttccat attttcctat
    93421 tattctaggt aattcactta aagttccttg tccaaaattt attcttgatg gttgataaaa
    93481 gttaatcata tttttcctcc cttaaattat tgccttcata ttcaaattat acatatcata
    93541 ggatttttaa ggcaatacct tcactgttaa ctcttattta ctaaagctta tggcaattat
    93601 tagacaataa atgttttatt attaccatat cattatgtaa attttattaa gtacccatgt
    93661 tataatttta taatcaatct tattgtataa ttgacttaat aataaaaata gagtatatac
    93721 acttttttat gacaaatagc ttaaaggaga attaaattat gaaatatttg atagacagtg
    93781 ctaatcttga tgaaattcaa aagtgtttaa agtatggatt taagggaata acagctaatc
    93841 catctatgta tcttaaagag aaagtaaact tccatgaatt tattgagaca tgtgctaatt
    93901 taaatccaga aatattaact gctgaagtca ttggaaataa tttatacgaa ttaattaatt
    93961 catgtgataa gatattaaat ataaataaaa acactataat aaaaataaat ttctctgaag
    94021 ttggcttaga acttataaac atattaaata gtaaaggtgt aaaaactgca tgtaccttga
    94081 ttttcaatgt aaatcaagca tcattagcta taaatgcagg tgctgattac ctattccctt
    94141 ttataggtag aaatgatgaa aatgggaatg atggtataaa aaaccttaca gaaatatgta
    94201 accttatatc aataaatgga tataatacta aagttgttgc agcttctatt aaaaatgtat
    94261 tccacttaac tcaagcatct ctttgtggat gtgattatgc agctgtaaca tatgatttat
    94321 ttaaaaaagc ttcttttaac cagcttacaa tagatggtgc caatactttt gaaagagatt
    94381 ggtccaaggt taataaatag taactaagat ttaggagggt ttgcattgaa caaaagatta
    94441 ttagatattg ctgaattatt actcaacagc tcagactata ttactgtaga tactattgcc
    94501 gaagaattaa aagttagtaa taaaactatt cgtaatgacc ttgttatttt agatgaatgg
    94561 cttttagagt ttaatttatc cctagataaa aaaactggtt caggggttat tattctaggt
    94621 aatgaagata taaaacttaa agttattaga gatatcaatg ataaatcaaa ttgtatatat
    94681 gcatactctc ctgaagatag aaaaaggtat attctaagta aattatttat taaaaattct
    94741 aagtttagga ttcgtgatat ttgcaatgaa ctacatgtta gtagagctac tgtgcataaa
    94801 gacttggtag ttattcaaaa ttttttgcaa aactttaaag tgactctagt tagaaaaacc
    94861 aataatggag tatatttaga gggaaaagag aaagatattc gaaaagcaat ttttgaactt
    94921 gctactgtta ataaaagtta tactgaactt aaagaaatat tattctcgaa atctaatgaa
    94981 tgcaaagata ccccatcaac aaaaatattt aaggagctat ttaactatga ttttgagaaa
    95041 ttatctcaaa tcactctaca caccttacaa gtagaaaaaa gtaaccttag tgatgagtat
    95101 tatataaact tcttaataca tatagctata tgtattaaaa gaatttcaat taaaagatat
    95161 attaacttat ctgaaggttt ttttagagaa ttattagaac atgaatactt tgaaaaatca
    95221 aaaattttat gtgctaacct aagtgaagct tttgacgtag aatttattga tgaagaggtc
    95281 tgttacatcc ttcttcatat agaaggatta cttaaatcaa taaagaaaac tactactctt
    95341 gaacctctta aaaatgaaga aattacagag tataatctat ctgaagcaat agctgttcat
    95401 tggggaagta tactaaattt aaacttaaag gacgatttaa tattaataaa gtctcttgct
    95461 aatcacctta aatcagttct acacagaata aactatgggt ttactattac aaatcccata
    95521 ttaaatgata taaagagaac atttccttat acttataagg ctgctaaaga gtctaatact
    95581 gttatcaaac agttgatgaa ttatgaagtc aatgatgacg aaataggata tcttgcttta
    95641 tatttaatat cagcaataga tagaagcaaa tctcccctaa atactatttt aatatgtcac
    95701 tgtagtgatg gtgtatctaa tttattagtc caaaagttaa gttttgaatt taatcagatt
    95761 aatatagtta aatctatacc tctatcttct atttcattta cgaactttga tgatgtggac
    95821 ttaatactaa ctactgctcc tgtagacttt gaacataatg ctgaactgat aaatataaat
    95881 gctcttttaa gtaagaatga tatttctaga cttagtacaa ttataaaaaa actatattct
    95941 gaaaaaaata aaatattatc ttataaataa acaaaaatag gcttgtctca acatagagat
    96001 aaacctattt ttcattgtcc aaatgataaa aatatatttg atttcataga aaaagtgcct
    96061 catgaactaa aaaattcatt ttgagacacc ttcatttttt atatttaatc tttttattta
    96121 agcttttata ttttttaaac ttttatattt aaagtaaatt ttattatttt tattgagcac
    96181 aagcattatt tatattatta atttcttcag tattcttacc aaactttgta gttacaaatc
    96241 ctattgtttt tattatgagt aataaggata tcaatgaata tatagatatc ataaaattct
    96301 tacttattat tccagacgct actattataa atccatctag cataaataat ataactggca
    96361 acttcagaaa cttaattacc ttattaataa gcattgcaac taaatcagtt ccaccagtac
    96421 tacagcccct tattattgct atccctatag cagttcctac caataaccca cctatcactc
    96481 ctgctactaa tagattgtca gttatgtgag tttgtggtat tacttttaag aataatgggc
    96541 ccataagagt tatatataat gtttttattc caaaaccttt ccctaaaaat aataatccca
    96601 ttactaaaag tggcatagat attcctaatg atatattctc aacaggcatt gataagaatg
    96661 tgctaagtac gactgataat cctgttatac ctcctggagc taatgtatgt tctgcaaaga
    96721 aaaaattaac tgctaatgcc attaaaaatg ctgatattgt tatcagtaaa taatctttta
    96781 tcatttcttt tttcatttaa taacctccta tgattatatt gtttcagtat aaaaaatcaa
    96841 ttaaattagt ctagcttcct gtagtttttc ataaaattaa tgcttcctta aaacattaag
    96901 aaagcatctc ttttatcata gtttattatc ttattctaaa ccaaactttg tagctgcttc
    96961 atctatagct tttctacaat tcttaacacc tgctgttata ccatctttat ccttgaatat
    97021 tgctgaagat aatattacaa cgtctgggtt acattctatt aatggctcca tattgtctga
    97081 tcttagtcca ccatctattg ctaattcaca cttaggattc ttttcgtcta tcatttttct
    97141 agctcttttt actaaatcaa cagcactctt tctccatccc cagttatctt ttccatcagt
    97201 ttcatcaaca ccatgaacga ctatttgcaa tctgtctata tcatatatag cttcatcaac
    97261 aaaacataat ggtgtgtaac atccaattgt taatcctact ttcataccaa attctctaca
    97321 gtaatttatt atgtatgcaa gaggagcacc taaaaaatgt tctgctggta ttatcaacaa
    97381 gttacatcct gctgctgcta ttttttctat aaataatcta tcacaatctc ttgtgtatat
    97441 atggcattct attggtttat ctgtcactgg tcttattgct tctattattt gatgaccacc
    97501 cataagttgc atatttttta agtcatgcat atctgctgca tctgaatgta cgtagtctac
    97561 acctgcatcc attgcttctt taactacggc tgatatatga ccgtaattta catgtgctaa
    97621 tcctgctgct atttttatgt gtttcatatt tgtatacctc catattttac tttaattagt
    97681 attaaatatt agtttttgat atttttttaa tattttttaa tccagtatta cttttattta
    97741 gcattacttt tattgctgta tatatttctt ttatgaactt attctgcttt tgttaactgt
    97801 gaacttattt tgctttgtaa attaatatta cactgatata ttttttttca caacactttg
    97861 actactcctt aaaagtacct ttatattgtg gtaaattata gacattaatt gtatataaaa
    97921 agttagtttt ttaccacatt cttatggcat ttattgtcta tactaactca attgatatag
    97981 ctagttcatt taatatataa tcagactata aatataaatt tactcgataa aaagtaccat
    98041 tcataacaat attaatgaaa gggagatgta aaatgagaaa ctgtattatt gcccaatctg
    98101 gaggccctac agctgttatc aatgcttctg cagttggtat ttatgaaaaa aatttagaaa
    98161 ctaaatactt tgataaagta tattttggta tcaatgggat tgaaggtata ttaaacaaaa
    98221 atataataga ttcagactcc ttaaacaaag ataatgtatt aaatttaaag caaacacctt
    98281 cgtctggtct tggttcttgt agatacaaac tggctgatta taaaataaat tcttatgatt
    98341 atgatagagt tataaatata ctagatgaat ataaaataga tacattattt tatataggcg
    98401 gaaatgattc tatggacaca gtgatgaaat tttctcaata ctgcaaaaac actacttgta
    98461 aaataaaatt tataggtatt cctaaaacaa tagataatga tttattagga actgacaact
    98521 gtcctggatt tggttctgct gcaaagctta tttctacact aataatggaa acatacttag
    98581 atttttctat atacaaaaat aatggtatat ttatagtaga aactatgggt agagatactg
    98641 gatggttagc agcttcttct tcactagcta gacttaatga tactccactt gttgatttaa
    98701 tataccttcc agaaattgat ttctatgaag ataagtttat agaagatgtt agaaaaatat
    98761 ttaaagaaaa aaataaggct tatatagttg catcagaagg tataagggat aaatacggca
    98821 actttatatg cgaacaaaaa acttctgctc atgataaatt tggtcattcc caattaggtg
    98881 gagtaagcaa ctatctaaag aatcttatag tatcatcatc aattacaaca agagtaaaaa
    98941 ccttagaact tggtgtaata caaagatgtg ctatgcattt agcttcagat actgatttaa
    99001 aacaagcagc tgaagttggt gcatatggga tagaactatc taaaaaagga tatacaggag
    99061 ttatggctat cattaataga acatgcaata atccttataa gtatgaagtt agtcatactg
    99121 atatttctaa aatagctaac aagacaaaat attttcctaa agagtggata aatgaagaat
    99181 gtaattatat aactaatgaa gccctaaatt atctatatcc acttattcaa ggtaaaccag
    99241 atatcaaata taaaaatgga ctaccttatt tttcaattat ttactaggaa attattataa
    99301 tttgatatac actcaattct atcgctctta aatacctaag tggctgttaa ataaaattat
    99361 aaattgttat atgacagtca cttaatcgtt taattattta actgtttagt tttttaattt
    99421 tttaatcttt ttaatactaa tacaatttgt tgtaataata tctcacaccc attttcattt
    99481 tggatagatt ataattagtt agacaataaa tattttgtca tgatattatt atatatagtg
    99541 atacaaatag aaatactttt atcatggcta gaaaaataaa gattacacaa aggatttaaa
    99601 agtcaaacaa cttcaattaa aataaatggt taaaataact tctaaatcaa ctacataaac
    99661 aataaaagaa cataaagtag ttaaatctac aattataaaa ttagtaagac tataataact
    99721 taaataaaat taaagttaac aaagactatt aaagttagca aatattcctc tacctaaata
    99781 attgcttttt ataaagagtt atttatttta attgaattta attgaaatac gattttaact
    99841 agaacaatag attaatgtaa tatttaatat aaaataatta taataattga aaaggaagta
    99901 atctatgatg aaaatagcag tcataacaac cgaattttta aaagagtttg tagataattc
    99961 tataaaaaag ttaaatatta atgcagaaat tgaaatatat atctatagag atttttctca
   100021 tgttggagat ttatatttag aaatagaaga taggtttgat ggatttgcag ttagtggccc
   100081 tatccccaaa aaagctatta caaaaaaggc tggaactatt aaaaaacctc tagttgattt
   100141 tggtactgac ttacaaagtt actatgatat gtttctaaag cttatcttta aatataatac
   100201 attagatttt tctagagcat actttgactt aacagactgg gcagataatc caaaagatat
   100261 atcatattat ttatcaaatg gcacatttgg agacttaatg gatagtattg atgaaaatgc
   100321 atctaaaatg agtttatctg acatagcaaa acttgaaaaa aagattgcaa aaaaacatat
   100381 taatctatgg aatgaaggga aaatcgattt ttctactact cgttttagta gtattgttcc
   100441 tatgttacaa aatgcaggag taaactttca tttcatatac cctgatatag atttattaaa
   100501 aaatactttt aataacttaa taaaagatat tcatttacat agaatgaagg gaaatcaacc
   100561 aagtgtaata tatataacag ttaaagatac aaattatgat gactctactc tagaccaagt
   100621 ttataaaata ttaaatagta ttaaaaaaga taaattaacc gattttataa ttgaaaaaaa
   100681 tagtaattct tttaaaattt tcactaaatg tgaaacgatt aaatcattaa ctaaaaattt
   100741 tactgcatgt tatataaaag aatctattga aaatagtaca aatattaaag tatgtgttgg
   100801 atatggaatt ggtaatgata taaagcaagc tatgtctagt gccataagtg ctaataagga
   100861 atctaaaata aatcatttaa attacagttt cttagttaac gaaaattatg agacaatagg
   100921 acctttactg tgtgataagt tacttactgt ttcaaataaa gtaactccac atataaatac
   100981 aattgccaaa agttctaaat tgtctactct tactattcaa aagattatat ctgttactga
   101041 aattctacaa agagatgaag ttactcctaa ggaattatct tcatgtttaa atgtaacagt
   101101 tagaactgct aatagatttc taagtagtct cttaaagtct ggaaacgcta ctatattata
   101161 tgaaaaacaa aactcaacaa aaggtagacc tgaaagggta tacaaattat ttatatcaga
   101221 aaataaatat taaaatccaa aatgcataaa aatattttat catctaatat taagtaaaat
   101281 tatatatgac tttctaaaag gtatatcttt gcatcttttt aagatatacc ttttatgata
   101341 tttaataata ttttatgtta ttatctacta aaattatttt ctaaccattt tactgcacaa
   101401 tgagcaaata aagctgaacc ataaactaat ccctcttcat taaaaattgc tttaggatta
   101461 tgcataccaa aattatatcc ctgactaata cttcccattc caatccataa aaatactcct
   101521 ggaaccctta gtaaaatctc tgaaaaatct tctgaaccca ttgcagatgg aaagtctatt
   101581 acattttcat ttcctataac ttctttaaca taagatacaa tctcatctcc tacatccaaa
   101641 tcatttataa ctgcaggagt ccccatttta aattccactt tagcatttcc tccaaatgat
   101701 ttagctattc ctgtagatat ttcaataatt ctatttttta atttttctct aacaaattgg
   101761 tcaaatgttc ttaaagttcc tgacatagat gctttatttg gtatagcatt tggtacgttt
   101821 cctgcattaa acataccaat agttaaaact acaggttctt tctgaggttt ttctcttgaa
   101881 agtatagtgt ttaatgctat ttgtatatgc gacattatgt ttattgggtc cactccaaat
   101941 tcagggcttg ctccatgagt tgcttttcct tctactgtta tttcaaatat atccgcagat
   102001 gccatagctg gaccacgtga ataagctact tgacctgtgt taagaaattt acccaccata
   102061 ctgtgaaatg ccatagctgc atcgacctga ggattttcta atataccatc atcaatcatt
   102121 gattttgcac ctctggtagt ctcttcatct ggttcaaata caaactttac tctaccttta
   102181 agtaagtgtt tattatccat aagtatttta gctgctccta agagcattgc tgtgtgatta
   102241 tcgtgtccac aactatgaga tgcatcttta ttcttacttt taaaaggtaa atccgtctcc
   102301 tccataatag gaagtgcatc catatctgcc cttaataata aggtctttcc accattttca
   102361 ctgtctaaaa cagctactat tccattatta gacgtcaatt tcggagaata tcccattttt
   102421 tctaaagtac tggtaacaaa ggttactgtt ttcggtatat tgcaaccaat ttcgggattt
   102481 tcatgtaaat atcttctcca tctaataatt tccccttcta ttgactgcgc ttctttaaaa
   102541 aaatttttca tattccttcc tcctaatcag atagtcagca aaatctcact ttcttttagt
   102601 aatgaaatga tgctgatata aaaattataa ttttatatat taaatttcat gtctttttaa
   102661 ggagttggaa tatcatctgg aataggacat ttatatgttt taccattcat agatttatca
   102721 aattcttctt ttgccttttt agctatctct ggattattta atattttagc tccaaacata
   102781 gccataatct ttgatgcata tatcatacct ttttctccta tagaacttcc tgcacaagat
   102841 gtaaactgcc agctatgacc tggtgctcct agattcgtac accctgtaaa aaagtatgct
   102901 gtcggaacta tatgcattac atctccaata tcagtagaac cataactatt aaagtttgta
   102961 acatttcctc caccataata tagatgagtt ccttctggca aattatattt acttatcata
   103021 gccttatatt gttgtgggct ttgtctatct aattcagctg caaaatccaa ttcctctcga
   103081 gtccaaggct cttgtttaat ctcattcata cattctgata caagatttgc taaaacatga
   103141 ttgtttaaag tattataaca acctcctaaa aactctactt caacttcagt ttcagtcatc
   103201 attgcagctc cttttgctac ctttacaagt ctttcatatg tactttctac agcttctcta
   103261 cttaaagctc ttgtataata ccatactgat gctttatcag gaactatgtt gggtgctact
   103321 cctccatctg taattgtata atgaatcctt acatcagaag taacatgttc tctcaaataa
   103381 ttagctccca cattagtaag ttccacagca tctagtgcac ttcttccatt ttgagggtct
   103441 gagcctgcat gcgcagtctt tcccttaaag tgaaacttta cagagttaac agctgttgaa
   103501 gtaccaattg tagcttcact aattttattt ggatgaaaat ttatagctaa gtctaaccct
   103561 tcaaacgctc cacctctagc cataaatcct ttacctgtta attgttcttc tcctggacat
   103621 gcataaaata ctatagtccc acttaagtta ttttctatca tctctctttt aagccctact
   103681 actgccccta catgtgctgt acataataaa ttatgcccac atccatgacc atatgcaccc
   103741 aattcaaatg cttcttgctt tgttgaaact ttttgattta aaccaggtaa tgcatcaaat
   103801 tctcccataa aacctataac tggtttacct gaaccaaaac tagctctaat agccgtggct
   103861 aaacctccta cacctacttc cacatcaaat ccttcacttc ttagaaagtt tgctgtattt
   103921 tcacatgctt taaattcttt aaatgctttt tctggatttt cccatatttt cttacttaaa
   103981 tcatcaagtt tgaatctttt tttatctatc tcatttatag atatacttcc tatcatttcc
   104041 tattcctcct ataagtatat ttactatcaa ccaaatataa ttggacctat tatactagca
   104101 aatgccactg atgcaatggt tacagtaaca aatcctccta taatcatctt tggtaataaa
   104161 taatctgttg ccctttgttt ttcttcttca gttccttcca tagcatcaat accttcgttg
   104221 gaaattatct gtgttgcagg ataagctagc atacaagtta caccaattgc agctgacatt
   104281 cttggagaat atcccaatag ttttcctaca attgcagtaa ataatattat aaatacagag
   104341 cctacaacaa gtattcctat agttggaaca atcatcccaa acaatgctgt tggagttacc
   104401 ttagcaagtc ctccaggtaa catcaacata caaccaaaca ttataattcc attagattga
   104461 gatttatcta aaattccttt ttctaaaaaa cctattcgtg taaaaatcaa ccctactaac
   104521 aaacatgcta tattaggatt taaataatag tttgcagggg taaatcctgg tattaaagta
   104581 gccaatccta caaaattacc aatcatagca acaaatgaaa gctttgcaag atacactaga
   104641 gtagatgatt ttttacctaa atcttcttta aaaattctca tacttggaag tttaaaatta
   104701 ctttttgact catctttcaa aaaatcccca ttatctcttt taaattttaa ttctttattt
   104761 atacaatatg tagttatcgg aatgccaaag aacttttgaa atgataatac tagaattaca
   104821 aatgcagcaa gttcaggtct atttgcagct tctgcaacag ttgttacgat aataccagca
   104881 acagtagaac ccgctattgg aggtgctgct attaaagcat actctctacc aaataacata
   104941 ctacccactg ttaaacagcc aacccctatt cctacaatac ctactaatgc aattacaacc
   105001 gttttccatt catgacataa gtcttcaaga tttataagtg ttcctaagtt agttattaat
   105061 aaagctatac caaagttgct cattgcagct aatatccctg atgctcctgt aatgtctttt
   105121 ggtaaaatat ttgtccaaaa tcctattaaa aatataatac atacaaataa caatgttgaa
   105181 attgcacctt ttgttttctt agataaaaac tcactaaaag cataaatcat tacacataca
   105241 gtaaagcaag taagtggatt ccaaaaattt tccattgttg tttcctccta aatataataa
   105301 ttttttatca ataaaacaat aattataaaa tgtatattat gcagttattc ttaactacat
   105361 atggtatagc ttgatatttt ttgatgatat tatatgcgtc ctaaattatt cctaaaatat
   105421 ctaaataaat ataactagag ttaactctct aaatattaac tatagttatc aacttactag
   105481 atttcttttt gatttttact ttctacataa ttttacgagt tagaattgta cttcaactac
   105541 tctctatatt agtatacatg ttggaagact tatatttatt taaatattag atatagaata
   105601 catttttgca aacgtcttaa attattctta aaatatctaa aacgaaataa taatataccc
   105661 attaaaccaa tattatcaga atatacttca ctttaagtct tctttatata gaaattttat
   105721 ctattagtgc atcccctcct ttgtaaatta gactatttct aaacgaattt agatatctta
   105781 ttcctaggaa ctattactag aaacaaaaat tatttattat attaaatcaa tgataagcca
   105841 tactttaaaa ttctttctat acaagtatga tttatcatat aatgacatct atacctttat
   105901 ctttatagta gtcctaaatt attcttaaat ttacaataaa aataatttca ctatttataa
   105961 aaatacttgt ttttatattg tcaaactatt cttaatatag attataattt taaatctttt
   106021 ctttgtcaat atattctgac atttttccag aaaatttata aagttatata gtgagtaaat
   106081 catactattt ttatataatg agtaaattat actatgaata tgtctaaata tttacttaag
   106141 tataaacata aaaaatgtgt attctccttt ttatagtaat tttagttgcc attactttta
   106201 agaagaatac acactttact ttaaagaccc tatactctat tttaaatgct ttactagaca
   106261 ctaattaaca ttagttccta acttctattt atcttattcc taccctacta ctatatccgt
   106321 agaaaaatct aaaacttctc cattagattt tattacttct ttgtaccaat caaatgattt
   106381 tttcttatat ctcttaaaac ttcctttgcc ttcatcatct aagtcaacat agataaatcc
   106441 atatctctta ctcatctgac ctgtagttgc actgactaaa tcaattggtc cccacatcaa
   106501 atatccaaaa cattcaacat tatcctcttc aattgcagac ttcatttgag atagatgctt
   106561 acttaaatat tcaattctat aatcatcatt tatagttcca tcttcttcga ttttatcata
   106621 tgcccctaaa ccattttctg taattaagat aggtaattga tactttctgt aaatatagtt
   106681 caaggtaaat cttaaaccta tagggtctat tgcccacccc cacttacttt gttccaaata
   106741 tggattttga atcccaccaa ataaagattt atcacctgat aaattttctt ttggagtaga
   106801 tacacttgaa aaataataat taagtcctat aaaatctaac ttaccttctt taaatgcttt
   106861 tttgtcttca tcagtcactt caatagttat attatttttt tcatattctt ttaatttata
   106921 ttgtggaaac ttcccattgc acattgcatc aatttgataa taatcacggt cattatctaa
   106981 aaatgcattt aacacattac taggattaca attgtatgga taaattggat ttagtccaaa
   107041 tacacatcca actttattgt tgggattgat ttctctagcc aactttgcaa cctttacacc
   107101 cgccaaagtc atattatacc ctacatttgc caatgtttga accttatttt ctatttcact
   107161 atacttaata cctgctatca tataagtaaa aatatccgag tgctctgttt gagggtcaat
   107221 atggttcatc tcattaaatg taacccagta ctttacctta tcatcaaatc ttcttattac
   107281 agtctcactg tactttaaat acaaatctat aagttttctg ttattccatg aaccatattt
   107341 atgtactaaa ttcataggta attcaaaatg atatagtgtt acaataggtt ctatattatt
   107401 ttctattaat gtatctatca gaccttcata gtatttaatc cctaattcat taggattttc
   107461 atcatctcca tttggaaaaa ttcttgacca atctatagat attcttaatg cactaaatcc
   107521 catttcttta aataaagcta tatcttcttt atatctatta taaaaatcta ttccattatg
   107581 agatggataa tccaattttt cttctatttt atcagtaatt actcttggcg tttcataaga
   107641 gcccttagtt acaaaatcca taattgcagg tcctttgtta tcactatccc atgaaccttc
   107701 acattgatgg gctgcaatac ttcctcccca gaaaaatgta tctttaatat tcatgaattt
   107761 tccctcctaa aatttatact attacagtta ataattcttc tgattcatca tttgatgaga
   107821 ttacatctaa ataatcgcta gtatttgtaa ctacagttat tatagtagaa tcaaagcctt
   107881 cctctataat tttatcagat tcaaatactg ctaaagcatc tcctttttta accctttgat
   107941 tttgtgttac aagactttca aagaattttc catctaagtt tacagtatct atcccaatat
   108001 gaattaatat ttctaatcct tcatcagtca ctataccata tgcatgttta gttggaaata
   108061 ctatagttat agttccatct acaggagata taacagttga ttttgattca ctaggtataa
   108121 ctccaacccc tttacctaat gctccagatg aaaatgcttt gtcattaact tccccaagtg
   108181 caattacctg accttttgca acatttccaa tactaatagt tcttgaattg ttctcgttga
   108241 ttattagttc taattctttt tcattatcac ccttaacttc ttctttttca tctgaaggta
   108301 ttcctagtaa ataggaagct gctgttgctg ctacaaatga tactactaca cttattatca
   108361 taaatgtaaa gttagatacc tctcctccaa caagatatgt tggtaatgca gctaatcccc
   108421 aaaccattcc atatgtttta acttgagcta aacctgctat taaaccacct atacctccac
   108481 ctatcattac tgctacaaat ggtcttctat atttcataaa cacaccaaac actgaaggtt
   108541 ctgtaactcc cataagtgca ctaaaactta ctgtaccaaa taattgtttt tgttctttat
   108601 tcctagtttt taagaaatat ccaaacattg caccacaaac tgcaatatca gatattgttg
   108661 cagcgcccat aaaaattggg tcatacccca atgttgtcac agaatttaaa gatataggca
   108721 tagtaaagtt tgctgcacca aagactatta agagtggttg taaagctgca tacagtgcaa
   108781 caacactcca attacccaat gtatcaatta aaaacataca tgcatagttt aatccatcac
   108841 caatccacat accaataggt ccaaatacag ttaatgtaat tgatagagtt attattaaag
   108901 ataatactgg aactaaaaaa tagtgtaatg ctttaggtaa tatttttttc aaaccttcaa
   108961 ttataattcc cattgcccat actcctaaaa gtattggaat aaaactgttt gcataagttg
   109021 tagcctgtaa atttatacca aataaactta atccttctac accatctatt gatgaagata
   109081 ataacgtaac tgctaacact actgctatat agggatttac attaagtctt tttgctgatg
   109141 ctattgcaat taatactggt aagaagtgaa atgtagcact tcttaatgta tctaatattt
   109201 gatatgtagg actgtcactc tgaagtatgc cagacatatt taaaagtgct aacatacttg
   109261 caagtatacc agctgcaagt agtacttcaa ttactgaagt catagtctct gagactacca
   109321 caaagatgga attaaatata cctttgatac ctctaattcc cttttttctt tcacttttta
   109381 tacttgattc acttgaactt aaacctatca tagacataaa ctcgttatat acatctacaa
   109441 catgagtacc tattataatt tgataagcaa catcattaga aactacatca attactcctt
   109501 ttaatttttt aatttcttct gtttgagcga tactcctatc atttaaagta aatcttaaac
   109561 gagtaacaca atgcgctacc gactttatat tttcttttcc ccctataagt tttattatat
   109621 tttcatttaa atctttatat ttcatctgat tttgcctcca gtctttgagt caccctattt
   109681 atatgcaaca ttaaataagt ttcttcactt atagatatat cgacattaaa ttgtgatttt
   109741 atatattttc ttatcttttg aacacttcca aatgactttg gataaagttg acttacttgt
   109801 ttatataaat ctatagaatt atcttcatct attgaagctt catccgacat aattctttgg
   109861 ataaagtact gtagatgagt agtaaatctc atataatttg ttgaagtttc atctagctct
   109921 acattaaaat gatattttat tatagaaact atatctgcta aagttctcaa ctctacaatt
   109981 gtactatcat gagactcttt atttacctcc atatttacaa aatgaagtgc tattgatact
   110041 gcctcatcat caggaagatt aagtccctta ctatcaccaa ttaattttag tgcatgcatt
   110101 ccaatttcaa aatgctttgg ataaaatctt ttaacattcc ataccaaagg actttttata
   110161 aattgattct tttcacatct tttaagtaaa aactctaaat ggtctagtaa ggttaagctt
   110221 agataatcac ttgactttat atttaaagct ttctcaccat attcaattat ttcattaata
   110281 agaactatat tattggagtc tgagttttgt agtagataac taaagtgttc tagcatatcg
   110341 tatgaatcta gtatatatgt tctctctatt tcattttcat ttattacttg tcccactctt
   110401 tttttaaagc caattccttt aacaaataca ataatttcat ttttacctct ttttactaag
   110461 gctacattat tatttaaaat ctgaattatt ttcatatatt cctcccttca ataaaaagaa
   110521 ctcaagcata tatgtataga gtatccctct atttttcaca tatatacttg agttctgcct
   110581 gctaatcagt aacatactca aaattatgac tacgtcgcca taattaaaat tcttttttgt
   110641 ttaatttcat attctatatg ttatactatc catataaatc tgtcaacggt ttcctagata
   110701 tttttttatt ctataactac aagctctgtt atgcgattat ctgacaaggt ttatatacta
   110761 aattgatact attttaccgt cactaatatt tataatattg tctgaaccat tatctatttt
   110821 actattatga attatcatag taatgctttt aaatataatg aactgtatgt taacaaataa
   110881 attcttaaga tatattaaca tataaagtct taagtttagt tttatttaat cactattaag
   110941 atatattaat aggtaaagct tcaaatttag tttcatttaa atgctagtaa gatat
//
LOCUS       DAMKNB010000004       106702 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.004, whole genome shotgun sequence.
ACCESSION   DAMKNB010000004 DAMKNB010000000
VERSION     DAMKNB010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 106702)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 106702)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..106702
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.004"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            170..1450
                     /locus_tag="PC494_000282"
     CDS             170..1450
                     /locus_tag="PC494_000282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HDF3910814.1"
                     /translation="MNILGLIVEYNPFHNGHIYHLSKSIEKTNATHTVAIMSGNFLQR
                     GEPALFDKYTRAKIAVENGVDLVIELPTLFACQSAEIFSHGAITILNSLNCINSICFG
                     SEEGNTEILYNIAEILANEPNEFKLLLKKYLDDGLLFPTARANALFDYIHQDKKNNFI
                     QNYSKEQLSKTLNSSNNILGIEYIKNLIHLNSSIKPFTISRVQSEYNSEEIESDICSA
                     TAIRTSLKENTDLFHLKNVIPEKTYNILNEKIDNGFLPMFDDFFFDILKTIILRDMDT
                     LKEYFEVNEGIENRIYKDIFTSEFLHELQLAIKSKRYTLTKIKRTLNNILLGIKKSDM
                     QLIKNIDTIPYIRILAFNDKGREILKEIKNKSEIKIINKFSNISFSLDDTIFKTLISY
                     DIKATNIYNSIYYKNNKDLVKGPMDFYTHPIYVK"
     gene            complement(1713..3104)
                     /locus_tag="PC494_000283"
     CDS             complement(1713..3104)
                     /locus_tag="PC494_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HDF3910815.1"
                     /translation="MYKLIDKKDIDFLIDTCGEENVLVGSDINEDFSHDELGGIEKYP
                     EVLVNVLETEQVSKIMKYAYKNNIPVTPRGQGTGLVGAAVAINGGIMINLCKMNKILE
                     VDYENLTLTVEPGVLLMTIGQYVQDRDLFYPPDPGEKSATIAGNINTNAGGMRAVKYG
                     VTRDYVRGLEVVLPNGEIINVGGKVVKNSSGYSIKDLLVGSEGTLGIVTKAILKLLPL
                     PKKSISLLIPFPDLSMAIETVPKIIKSKSIPTAIEFMERDVILAAEEFLGKKFPDNTS
                     DAYLLLTFDGNSTEDIEKEYEKVANLCLENGALDVFISDTQERNDSIWSARGAFLEAI
                     KASTTQMDECDVVVPRDKIAEFIRYTHELQDKLKIRIKSFGHAGDGNLHIYILKDGMD
                     DNTWKIRLKETFDYMYKKSRELSGQVSGEHGIGYAKKEYLHESNSDAYMMLIKNIKLA
                     FDPKNILNPGKIY"
     gene            complement(3115..4335)
                     /locus_tag="PC494_000284"
     CDS             complement(3115..4335)
                     /locus_tag="PC494_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding protein"
                     /protein_id="HDF3910816.1"
                     /translation="MSKIVVNQDKITDLKRILEICPFGAIEEKSGIVEISAGCKMCKL
                     CVKSGPKGAFEFIESSKVQINKDEWRGIAVYVEHHNGNIHPVTYELIGKAREMASKIK
                     QPVYCVFVGKDIKDKCSNLISYGVDEVFVYDEDEFKDFRIEPYSKAIENFIDKIKPTI
                     VLVGGTTLGRSLAPRLAARFRTGLTADCTILDIQSNTDLDQIRPAFGGNIMAHINTPN
                     NRPQFATVRYKIFSAPEKIENTTGKITLCKVEKKELKSKIKVLSVKEKNKEVGLEEAE
                     VIVVASRAIKKQEDMEMIYKLADKLNAQVAGTRPVIEAGWIDAKKQIGLSGRTVKPKL
                     IITCGVSGAVQFVAGMQGADYIVAINKDDKAPILDVAHLALIGDIYDIIPKLIEKIEN
                     NKDNNQKYMASAAK"
     gene            complement(4349..5137)
                     /locus_tag="PC494_000285"
     CDS             complement(4349..5137)
                     /locus_tag="PC494_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003457975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit beta/FixA
                     family protein"
                     /protein_id="HDF3910817.1"
                     /translation="MEILTCIKQVPGTTSVEVDETTGVLKRDGVDSKMNPYDLYALET
                     ALRIKEDKKANLKVLSMGPPQAKKVIEESFMMGADEGALISDRRFGGADVLATSYTIS
                     QGIKKMGKVDLIICGKQTTDGDTAQVGPEVAEFLDIPHVTNVTKLIEVKDESIVVEID
                     MPNDLQVCEIEYPCLITVEKDIFQPRLPSFKLKLNTKDREIPVYSLDDFEDKDENNYG
                     LNGSPTQVVRIFPPKPNTDKNIVRGNADELSFALVNKLEELKLV"
     gene            complement(5154..6428)
                     /gene="larA"
                     /locus_tag="PC494_000286"
     CDS             complement(5154..6428)
                     /gene="larA"
                     /locus_tag="PC494_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nickel-dependent lactate racemase"
                     /protein_id="HDF3910818.1"
                     /translation="MVKLKVPYSKQGMILEIPDERFLGVLESKSDNYIEHKTQEEIVE
                     ESMNNPIGSNSLEELVKGKKNVVIITSDHTRPVPSRITMPIILRRIRNVNPEIDVKII
                     VATGFHRPSTREELIYKMGEEIVDNEDIVMHISTDDKSMCKVGILPSGGDLYINKLAY
                     EAELLIAEGFIEPHFFAGFSGGRKSVLPGIASAKTIMYNHCSDFIDSDNSRTGKLNNN
                     PIHEDMVYAAKVAKLAFILNVVIDKDKKIIASFAGDVEKAHTKGCRFVTELSKVNSIK
                     SDIVVTTNGGYPLDQNIYQSVKGMTAAEATCKDGGVIIMISACNDGHGGQSFYENVAN
                     ADSPKQLLDKIRSVDRVDTIPDQWEFQILARILSKYTVIMVTDKCNPEMIKKMHMKHA
                     FNFKEALEMANSIVGKESKVVVIPDGVSVIVK"
     gene            complement(6546..7259)
                     /locus_tag="PC494_000287"
     CDS             complement(6546..7259)
                     /locus_tag="PC494_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FadR family transcriptional regulator"
                     /protein_id="HDF3910819.1"
                     /translation="MFNSIASKKVYEQVIEQIQYKILNGELKKGDKLLSERELSEQMN
                     VSRTSIREAIRVLETMGVIESRQGEGNFICTNIEKTLIEPLSMIFKLNNGTLEDILEL
                     RIILEIEIAKLASKRITSSEVIELKHIIDEMRVETNKKDNNRVLVLLDQKFHSKLATL
                     SKNYLIQSLFMTASKLFDGFIEDAREKIIAEPFNENILLKQHEAIYNAVVENDVELAC
                     EKAKEHMDFISKNYRKNEN"
     gene            7384..8643
                     /locus_tag="PC494_000288"
     CDS             7384..8643
                     /locus_tag="PC494_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation integral membrane protein YlbJ"
                     /protein_id="HDF3910820.1"
                     /translation="MKKNKIIAFFAPSIIVGVLVLGIILYPNEAIRSAREGFSIWSNV
                     LVPSLLPFIIGANLIVDLKIVDIIGFIINPITRFVFNVSGKSALAFAISTVSGYPVGV
                     SLASEFRSNGQISKYEAQRLVSFCSTSGPLFIIGSVGTGMFQNSNLGYLMILCHYLGT
                     ILVGLFFRNYGNENLPKTKLDLKTNIKNVINIRNSSGNGFFVLFGNAVFNGVNTLLTV
                     GGFVIVFSVVFKILSLFNVISLIASVIYLPLSFLGVSKELCQAFVSGLFEITIGCNKV
                     SSITSSPEILRASLASFLIGFSGLSILAQCCTFLSKTDIDLKLYILSKFAHGVLAAIF
                     IFILYPIANSAVLVSSFADTYNVIYNNLIWFYYLSYYDTILQVVVIIYLISAVFIAKK
                     HMKTLSTNGKLMRYKNTFFTKKFSRKK"
     gene            8923..9489
                     /locus_tag="PC494_000289"
     CDS             8923..9489
                     /locus_tag="PC494_000289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HDF3910821.1"
                     /translation="MATRPIEIDEYKKIMELLHTGFTYSENGVEKRFRKNPKVALALM
                     LEANLGLRISDILRLKIGNFKGNMLEINEKKTGKLQYRPVNKNIIESINEHARKYNLK
                     SNDYLVNIKTKAIQKQLRIICKHLNLYNISTHSFRKLYATTQFEKSNNNLELVKELLN
                     HSSVATTQRYIRVTQQAINEASENFFIG"
     gene            complement(9690..10895)
                     /locus_tag="PC494_000290"
     CDS             complement(9690..10895)
                     /locus_tag="PC494_000290"
                     /EC_number="1.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine dehydrogenase"
                     /protein_id="HDF3910822.1"
                     /translation="MKIAILGYGTVGSGLIDLIENNTSKRDIEVVGILVKNKEKHKYK
                     KYFDKITTDIEDIFDKDIDILVEVIGGLNPAFDYVTRALNKKIHVVTANKDLLAEKGS
                     DLIELANLNNVSIKFEASVAGGIPVLKPLIESLEGNNIKSINAILNGTCNFILSKMYD
                     ENLPYDVALKQAQELGFAEVNPDADVLGYDSARKLSILSTLSYGKIVYWKDLLLEGIT
                     SIDEKDIEYAKKLNCKIKLVARSKYESGEVSGFVRPALVDNNNMLSKIDNEFNVVILV
                     GDSVGELSFVGKGAGRGATGSAVYADIIDIIDNRSSNIKSFSKGKLDLSGLIEDECSA
                     VVRFGGYNNKDGILECLDKYVDSYDIIDDEELAIFVSAKSEHEIDRVLEIVKRNNYSE
                     SAKKLLKID"
     regulatory      complement(10998..11104)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00162"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="SAM riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF00162"
     gene            complement(11196..11564)
                     /locus_tag="PC494_000291"
     CDS             complement(11196..11564)
                     /locus_tag="PC494_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhbY family RNA-binding protein"
                     /protein_id="HDF3910823.1"
                     /translation="MLKGKQRAYLRSLANTLKPTTQIGKEGVTESFLEQLDGMLRTRE
                     LVKVTILENAGLDTKETANAVCEALRAEFVQAIGFKFTIYKRNIEEPKILFPGHEQAK
                     AKTKNNNVTKKGKPTKRAVR"
     gene            complement(11616..12893)
                     /gene="obgE"
                     /locus_tag="PC494_000292"
     CDS             complement(11616..12893)
                     /gene="obgE"
                     /locus_tag="PC494_000292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000469293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HDF3910824.1"
                     /translation="MFIDKARIFVKAGNGGNGSVAFRREKYVPAGGPDGGDGGRGASI
                     IFEVDLGLRTLMDFKYQKKYQAQNGGDGSKGKRAGKNGENLVLKVPAGTVIRDEATGL
                     VLADLKKEGDTAIVAKGGIGGKGNQHFANAVRQAPAFAKSGTDGEERWITLELKMIAD
                     VGLLGFPNVGKSTFLSVVTKAKPKIANYHFTTLTPNLGVVQTKFGDSFVLADIPGIIE
                     GASEGIGLGHEFLRHVERTKVLIHIVDISGLEGRDPIEDFDKINDELKLYNEKLSKRP
                     QVVVANKFDILEDESKFEKFKSELEGRGYTVFKMSAATRQGIDEVIAYVSKMLKEVED
                     VELVSEEEMYRPELDIGTEEELSIDIEDGVYVVTGKALRRIMYSVNFDDMESLQYFQK
                     AMESQGVFDRLREMGIEDGDVVKIYELEFEFYN"
     gene            complement(13004..13294)
                     /gene="rpmA"
                     /locus_tag="PC494_000293"
     CDS             complement(13004..13294)
                     /gene="rpmA"
                     /locus_tag="PC494_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HDF3910825.1"
                     /translation="MLNMNLQLLASKKGVGSSKNGRDSISKRLGVKRFDGQLVTAGSI
                     IVRQRGTKIHPGTNVGKGSDDTLFALVDGTVKFERKDKKRKKVSIYPVAIAE"
     gene            complement(13308..13625)
                     /locus_tag="PC494_000294"
     CDS             complement(13308..13625)
                     /locus_tag="PC494_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HDF3910826.1"
                     /translation="MIKVKYYYNDDFLLQGFCLKGHADFAEIGYDIVCAAVTSNAIAV
                     INSLDKLKKIEFEKVVGEEGHIECIVKDTHVKDAQLLLNHFQLAVKEIKREYPKNIKI
                     LKK"
     gene            complement(13640..13951)
                     /gene="rplU"
                     /locus_tag="PC494_000295"
     CDS             complement(13640..13951)
                     /gene="rplU"
                     /locus_tag="PC494_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012063435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HDF3910827.1"
                     /translation="MYAIVKTGGKQYKVSEGDVLFVEKLEANAGDVVTLNEVLACSKD
                     GELKLGSPVVEGASVQAKVVEQGKAKKVIVFKYKAKKDYRRKQGHRQSYTKIVVEKIN
                     A"
     gene            complement(14052..15473)
                     /locus_tag="PC494_000296"
     CDS             complement(14052..15473)
                     /locus_tag="PC494_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rne/Rng family ribonuclease"
                     /protein_id="HDF3910828.1"
                     /translation="MKKIVIESLIGSQKTAVLEDERLTELFVEDNLNKKTVSNIYRGI
                     VKKVIPGIEACFVDIGFKKLAYLQLKKGSTIKSGQDILVQINKEEIGTKGAKLNTEIS
                     ISGRYIVYIPSNDRTTISNKITDEKERFRLKKITKAVNKENLGLIIRTEAQGCTHDEI
                     KKDIEELKLKYENILKEYKLGIGPKLLYKSLDFATKYVKDNVNDDIESIITNSYDKYS
                     ELKSILRGIDKTYVDKLCLEENRDVFDLYRIESKIEKLLNKKVWLKSGGYLIIEKTEA
                     LTVIDVNTGKFIGTGKLDETVYKTNLEAAKEIVRQLRIRDIAGIIIIDFIDMHKKKHQ
                     KEILHILEEEFNKDKRKAEVLGMTKLGLVEVARRREKESIDKYYLMSCPCCDGEQTIK
                     SVHYILDSIEKEIMRISEHTVYKNIMVEFNDFIFEQIKEYYMDIIDKIGEKYNIKISL
                     NANSTLKHNKTNVIFDKIVDNKM"
     gene            complement(15491..16192)
                     /locus_tag="PC494_000297"
     CDS             complement(15491..16192)
                     /locus_tag="PC494_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2344 domain-containing protein"
                     /protein_id="HDF3910829.1"
                     /translation="MSKIIRVKFKKEGDMIYISHLDLQRLLQRAFRRAEINLSHSQGF
                     NPHPKMSYGNALALGTESQGEYVDIEIEEDDLSVEEFLNKVSIQLPDGIDFIKAKEID
                     RQTPSLSSVIDYGEYLFNIDLKRPMTKEFVKRKVIDFMNNKEIIITKKNKKGKMVEVD
                     IRPMIRTFDVLNLEDEHITLTATIATGSKTNLNTNILIPKILEMFELDIDPLDVDILR
                     RDLYVLEDGELVTPM"
     gene            complement(16194..18038)
                     /locus_tag="PC494_000298"
     CDS             complement(16194..18038)
                     /locus_tag="PC494_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03960 family B12-binding radical SAM
                     protein"
                     /protein_id="HDF3910830.1"
                     /translation="MNKVDLKKILKKVEKPARYLGNEINSIHKDTSNSELIRYAHCFP
                     DLYEVGMSHLGSHILYDVINKDEDVFCERVYSPAVDMENIMREKSIPLFALESREPIT
                     NFDFVTFTLQYELSYTNILNILDLANIPILKEERTLEDPFIMVGGPCAYNSEPLADFV
                     DVVILGEGEEVNLEVVNEYKEWKKNKTTREDFLYKISSIEGVYIPSFYDVKYNEDGTV
                     QSVTPNREGITKNPTKRIIKDVETVDYPEKLIVPYIDTVHDRIVLELFRGCTRGCRFC
                     QAGMIYRPIREKSVKRLKEILDKLVKNTGYDEISLSSLSTSDYSKLSELTDYLVDEYA
                     SNNIGISLPSLRLDNFSMEIADKIQQVRKSGLTFAPEAGTQRLRDVINKGVTEEDLEN
                     ATERAFEMGWNSVKLYFMIGLPTETYEDLDGIAKLAYKVIDIYRKVNGGKLKRSFSVT
                     VSTSTFVPKPFTPFQWHGQDTTEEVINKQRHLVNKLRNNNIKYNYHDSKTSLMEAVVA
                     RGDRRIGKVIYDAFRLGAKFDGWAEHFNLDIWKEAMEKNNLSIDFYAHRNRNYEEVFP
                     WDHIDVGISKKFLIREDENAKKEKITSDCRHNCNGCGINIHDIGRGLC"
     gene            18357..19550
                     /locus_tag="PC494_000299"
     CDS             18357..19550
                     /locus_tag="PC494_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FprA family A-type flavoprotein"
                     /protein_id="HDF3910831.1"
                     /translation="MSKVFEVKKDIYFTGVVDEGLKVFDIIMETEFGTTYNSYLIKDE
                     KTVLFDTVKANFKDEFLSNLSEVTDIAKIDYVVIHHTEPDHAGSLKYLLDINPNIEVY
                     CTKAAKLYLDGQINRPFNCHVIKDGEILNIGKRNLRFITAPFLHWVDTMFTYIEEDKT
                     LLTCDAFGCHFASVDAEVVNSEDYLKSAKHYYDCIVKPFAKHVLSAVDKVVGLNIEFD
                     TILTSHGPMLTKDPMAAVKRYVEWSTEAVNTTNQNQVSIFYLSAYSNTLEMAKKIKEG
                     LDKEGAKAELYDLEDMTLTEMHDTLVVSKVILLGSPTINKTMVKPMWDLFSVIDPMAN
                     QGKIAGVFGSFGWSGEGITMAETLLKSMSFKMPVESLKKKFFPSEETLKECMAFGAEF
                     AKLVK"
     gene            complement(19762..20844)
                     /locus_tag="PC494_000300"
     CDS             complement(19762..20844)
                     /locus_tag="PC494_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglutaminase domain-containing protein"
                     /protein_id="HDF3910832.1"
                     /translation="MKKIRKLATKLLIAMMVLTSCMSVTVYGMTAKDVTAKTPKSYVA
                     GTNSIYGPKLSQAQLNSVAQATADFMNKKITKNMTTDAKIRVAYNHIKNNTTYVNWNA
                     AEGANTAYTLVTKKGACSGMCRSLKALCDAMGIECYYVHSTTNDHQWNLIRFEDGRLY
                     HVDIDANKSAGADIIYKSLTHPLPFDKKAYPAVGEVVKTQNPTPTVKKPTPAKPSAPV
                     GPGNHTMIADQQGAILDEVYGNNLRPKIEMYEGVPCSLINSSINTIKFTSKNSNLDPS
                     KHTVTVIGFMNTPYGMVALAPDGVPDEYPFEYDKPFSLDFTGKNLSAAELSKKCKENN
                     VIIKVEIGETASNSGRGMVAYARYVN"
     gene            complement(21408..22199)
                     /locus_tag="PC494_000301"
     CDS             complement(21408..22199)
                     /locus_tag="PC494_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3910833.1"
                     /translation="MKLIDEYLDKLYKKCDNKSTIELKQEMRCHLIESANEFKLEGLD
                     EEEACKKAIERFDDGDEMQYELCNIIKELSLSLDRHKSIVMGFKKVLGYISIIAFLIS
                     GFMWYYNNSLQHNMYNLGKELDGEIKQLAERHDMTKIGEYKLELEKILDKDKYSKVKA
                     LRLYVIDMKDGNTNLSSSGLNANMVYEREADYNNISNFIQHLGYNGKDFLDKNGNIVN
                     PDIFLEYFFYFESEMLIPVAFAFGLLCIIAYFILRFKISLIKNNN"
     gene            complement(22203..22532)
                     /locus_tag="PC494_000302"
     CDS             complement(22203..22532)
                     /locus_tag="PC494_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF3910834.1"
                     /translation="MQLNKEVLKGYIDILIVSILEKKDCYGYEIAKQVRERSEFELKE
                     GTMYLALKRMESKNLIKSYYSNEQSSGGRRKYYNLTNEGKDFLEIKKQEWRFIKKVMN
                     QFLGEVD"
     gene            complement(23016..23429)
                     /locus_tag="PC494_000303"
     CDS             complement(23016..23429)
                     /locus_tag="PC494_000303"
                     /EC_number="4.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylglyoxal synthase"
                     /protein_id="HDF3910835.1"
                     /translation="MNIALVAHDQMKNTMVGFCIGYESILKKYGLYATGTTGKRIMDE
                     TELNINRLASGPLGGDQQIGSLIVTQEIDLVIFLRDPLTSQAHETDIQALIRLCDVYH
                     VPIATNLASAEIFIKALDRGELSWREVRKSKSQRI"
     gene            complement(23470..24600)
                     /gene="rodA"
                     /locus_tag="PC494_000304"
     CDS             complement(23470..24600)
                     /gene="rodA"
                     /locus_tag="PC494_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein RodA"
                     /protein_id="HDF3910836.1"
                     /translation="MKKININYKSTIKLIKQLDWKLIVTVLAIFIFGLVILSSATHAN
                     STGSYNQLIKQGLAFVLGIGMIIVILFFDYNLLGRYYKALYIISLILLAIVLLPGIGT
                     VKGGARSWINLGPLDLQTSEIVKLTFVLSYAKILESKKDKLNTLKEVMPVVVYSLPFI
                     GLLIAQPDLGTGIVFCCMIFAMLFTAGLSSKLIKRGIIILLVSMPLMYLMMADHQKVR
                     IEAFLNPEDVTLKGNYQVMQSLIAIGSGGVTGKGLYNGSQNQEDFLPVQDSDFIFAVV
                     GEELGVIGMAVLIILFMIFLLRLLAIARDAKDFYGTLIVVGVMGMFGYQIIQNIGMTV
                     ALIPVTGVTLPFVSYGGSSLLTSLANLGLVLNVCMRRKKINF"
     gene            complement(24685..24969)
                     /gene="minE"
                     /locus_tag="PC494_000305"
     CDS             complement(24685..24969)
                     /gene="minE"
                     /locus_tag="PC494_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division topological specificity factor
                     MinE"
                     /protein_id="HDF3910837.1"
                     /translation="MLDLFRVFSNEAKTSKSVAKERLKLVLVHDRVDCSPQLLEMIKT
                     DILKVIANYAEIEDDGLEIKMSKCRGEHDDKPVSALVANIPLKNIKDRCM"
     gene            complement(24987..25784)
                     /gene="minD"
                     /locus_tag="PC494_000306"
     CDS             complement(24987..25784)
                     /gene="minD"
                     /locus_tag="PC494_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum site-determining protein MinD"
                     /protein_id="HDF3910838.1"
                     /translation="MSEVIVITSGKGGVGKTTTAANLGTALSLENKKTVVVDADIGLR
                     NLDVVMGLENRIVYDIVDVVEGTCRLKQALIKDKRFDNLYLLPAAQTRDKNAVSVEQM
                     IDLCEKLKESFEYIIIDCPAGIEQGFKNAVAGADRAIVVTNPEISAVRDADRIIGLLE
                     ANEIKEIRLVINRIRNDMVKRGDMMDKQDIIEILAIDLLGLVPDDESIIISTNKGEPA
                     ILDSKSLAGQAYKNIAKRILNEEVPLLDLEVEDGFFGRLKKMFSMAK"
     gene            complement(25808..26491)
                     /locus_tag="PC494_000307"
     CDS             complement(25808..26491)
                     /locus_tag="PC494_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum site-determining protein MinC"
                     /protein_id="HDF3910839.1"
                     /translation="MSLREICSQELVEFKGNKRGIIVNIKREAPFEEIQEKIINKLEA
                     YVGFFNGAKISKINSDCLTDMEILELKEGITSRFDVEFVEDQKIEENSNFPTKYVNTL
                     RSGENIEFEGDVVILNDMKPGSKVLSKSNTVVMGDINAGAKVVAGGNVFVMGKIEGFV
                     HAGAEGNEFAYVVAGNLNPKILQIADNIAEAPDDEENYESESEISPEIAFVSNGRIVI
                     ESYLSKLDK"
     gene            complement(26589..29567)
                     /locus_tag="PC494_000308"
     CDS             complement(26589..29567)
                     /locus_tag="PC494_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HDF3910840.1"
                     /translation="MEENKQVDRLKIIKIVMGVIFLAILVKIIYMTTFKYEYYNELAE
                     NKTYKKLAIEAPRGEIKDRYGRLLAGNKNLFTVQVSGNDINKKDANKHSRANEISLKL
                     INLLERNGEEYVDEFPIYVENGKYYYTYDRDIREYKSENGIPNDYNAKESFYYLVDKL
                     ISAGILSQEDKRLDATRLQAKLNENGYYPPILVSKWMFTAERDKRDWLASYKIKETKL
                     SAKEAFEKVRNSDALEIDKSLSDEDARKIMVVRDLIKSKGYSQYNPVTIAKDVGETTI
                     AQIEESAMDLVGVSIAVEPVRYYPNGSLASHMLGYVGKMPSTQIESYLQKGYETGDMV
                     GLAGVEKSNESRLRGTDGYKMVKVDALGRISKEIESKKPKSGDTVYLTLDKDLQEVSD
                     NALKQIIEVASKGGTFKSKFGDKPISAYAGKAQSAALIAIDVKNGEVLASSSYPNYDP
                     NKFAKGISTEDYKALQPKNPNDLLAGSPLLNLVTQGEFQPGSSFKMLTSMAALENGLD
                     PNFTINDPGVIMLGKKSFGDYVWNHGRGNHGMTNLYKAIQESCNIYMATIGTGKTWPD
                     GKSIGIDMNANKILEYAKLFGLDQNTGLQDEVEERAGKVPSTEDKLKSTQALLKSNLE
                     REMANDFVDITREKNPKEYEKRINEIVSWAAEKKTPGRVETMNRLKKLDVKEDRIEEV
                     ADLAVFSYFNFAKWSTADTFNLAIGQGENAYTPAQISRYVAAIANGGNLVELSVVDRA
                     VSSDYSSVKINDQKKVEKIPFKNPDNLKELTKGMKLVVRQGTAKSAFADFPIDVAAKT
                     GTAEKSGKIPTDNEYEYLKSHMSSYNVNLNDAIKLADKMKAEKEKELSLAKEKEIKKK
                     LENKDLKDEERKKLEEELEDGVKVRLEDTDKVNSSYLRKAIKELNPKITDDQIDRFKQ
                     DYGSFTWTVAFAPADDPEIAVVFVIPQGDSSVFSLLPTREVIGTYMGLEPTNSKNDNK
                     TNDVNNSSDENINFESQINR"
     gene            complement(29579..30067)
                     /gene="mreD"
                     /locus_tag="PC494_000309"
     CDS             complement(29579..30067)
                     /gene="mreD"
                     /locus_tag="PC494_000309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HDF3910841.1"
                     /translation="MKKVLLCLLGIVLMTIENSITNYIDIFGISFNLVLIYVTIISLY
                     LDELEGGIIAAIIGLIKDITVGGIFGVNALILFIIAYAIGYMRDQLYKGSYIITFVLI
                     FIGSLIDSIVNIGTSSIIYQSYNISTLFVKGLLVAPIVNSLIGLVIYRLSKRAVLKLK
                     ED"
     gene            complement(30082..30975)
                     /gene="mreC"
                     /locus_tag="PC494_000310"
     CDS             complement(30082..30975)
                     /gene="mreC"
                     /locus_tag="PC494_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HDF3910842.1"
                     /translation="MALRFDKNKNEKKRINVKVIATGVVAITLIGIVGISIGKFSSGS
                     PVNLGVASDAITSVGKGINDGFSFIKNGFKDVANFKDNSKKVKKLEEENEKLKKNMIA
                     LNAKLDKTESLEELKKTLNFVQEEYKATSISASVVGKNDGNWYESFVIGAGKNSGVKK
                     ESIVMNGSGLVGIVYEVSNNYSKAISLLDSKASVSFKLAKDANAKGTITQNTTLDNKD
                     SYNSKGYLQGYMFDSSYNVIQGDIITTSGLGFFPDGIPIGEVEKVVDDKDKSLKYVVV
                     KPYVDFKNINDVVVIEPRNIG"
     gene            complement(30985..31995)
                     /locus_tag="PC494_000311"
     CDS             complement(30985..31995)
                     /locus_tag="PC494_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein"
                     /protein_id="HDF3910843.1"
                     /translation="MTKDMGIDLGTANTLVYIKGQGIVVREPSVVAIRDDSKEVLAVG
                     EEAKKMIGRTPGNIVAIRPMKDGVIADFDITQSMISYFIQKAADKKGVVSPRIAICVP
                     FGVTEVEKRAIEEAARQAGAKDAFLIEEPMAAAIGAGLKVEEPEGNMVVDIGGGTSEI
                     AVISLGGIVTAKSIRIGGDEFDESIVAYVKKEYNLMIGERTAENVKINIGSTFKDDEE
                     INMQIRGRDLISGLPKTIEICSTEVREALKEPVSSIVDAIKSTLERTPPELASDIMEN
                     GIMLTGGGALLRGLDKLITQETGMSVQIAETPLDCVALGTGKSVEDQEIFEKVLMMNT
                     KN"
     gene            complement(32116..32775)
                     /gene="radC"
                     /locus_tag="PC494_000312"
     CDS             complement(32116..32775)
                     /gene="radC"
                     /locus_tag="PC494_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HDF3910844.1"
                     /translation="MAPEERPREKMLAKGVKSLSNAELLAILLRTGNKNKNAIELANY
                     IINRDIQGIRHLEDMTIEELCNIDGIGLSKSTQIKAALELGSRVASFKPIKYKIMNPW
                     DIQRYYMDSLRYLKKEVFKAVLLNTKNEIISDVDVSIGTLSSSLVHPREVFKEAIRRS
                     ASKIIVMHNHPSGSVEPSREDKNITSRLIKCGEIIGIEIIDHIIIGDGLYFSFKENMI
                     I"
     gene            complement(32820..33404)
                     /gene="maf"
                     /locus_tag="PC494_000313"
     CDS             complement(32820..33404)
                     /gene="maf"
                     /locus_tag="PC494_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation inhibitor Maf"
                     /protein_id="HDF3910845.1"
                     /translation="MNIILASASPRRKEILENTNVRFDIIKNEIDEIILEGETPKHLV
                     MRLAFEKSMSVASEHNEDVVIGADTVVVLDNAILGKPKDESCARDMLKRLSGREHQVI
                     TGISLINLCEDKKVIDYVISNVKFKTLSEQDIEDYLKTNESFDKAGAYGIQGYGALLV
                     EEIRGDYFNIVGLPISRLGDLLKKYFSINLFYGV"
     gene            complement(33624..34595)
                     /locus_tag="PC494_000314"
     CDS             complement(33624..34595)
                     /locus_tag="PC494_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RnfABCDGE type electron transport complex
                     subunit B"
                     /protein_id="HDF3910846.1"
                     /translation="MVILTAVLVLGIMGLIFGIVLDFASKKFAVEVDERVEAILGVLP
                     GANCGGCGFPGCGGLANAIVEGNAPVNGCPVGGADVGAKVGEIMGISAEAGEKQVAKV
                     ICKGTCSSAKDKYEYEGISDCRAANVLNSGAKMCKFGCLGLGTCKDACKFDAISIVDG
                     IAVIDEEKCVNCGKCKEVCPKGIIITKPESQEVVVECNSKEFGKAVKEKCTAGCIGCG
                     MCVKACKFDAIIFEDKIAKIDPNKCVGCMQCVAKCPTKVISGDITKKKKVTIDQELCV
                     GCTVCKKQCKFDAIEGELKEKHKVDADKCVGCHLCMEKCPKKAIKIL"
     gene            complement(34611..35186)
                     /gene="rsxA"
                     /locus_tag="PC494_000315"
     CDS             complement(34611..35186)
                     /gene="rsxA"
                     /locus_tag="PC494_000315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transport complex subunit RsxA"
                     /protein_id="HDF3910847.1"
                     /translation="MNLILLFLSIVLVNNVITSQFLGICPFLGVSKKVDTAVGMGVAV
                     TFVLTLASIITYFIQILLVKTGTGFLQTIAFILVIASIVQFVEMVIQKMSPSLYQALG
                     VYLPLITTNCAVLGIALVNVQKSYNLVETIINGFGAGAGFTLAIVIFAGIRERLELAD
                     IPEAFKGFPITLISAGLMSIAFLGFTGLIKL"
     gene            complement(35201..35794)
                     /locus_tag="PC494_000316"
     CDS             complement(35201..35794)
                     /locus_tag="PC494_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transport complex subunit E"
                     /protein_id="HDF3910848.1"
                     /translation="MNLAKVFKNGLIDENPTFVQVIGMCPTLAVTTSAINGIGMGLST
                     AAVLICANLVISLIRKITPDKIRIPIFIVVIATFVTIVGMLLKAYVPALDKALGIYIP
                     LIVVNCLILARAESFAFKTGAMPSIVDGVGQGLGFTVALTIIGAVRELLGNGSLFGMT
                     LFGASFQPVLIFILPPGAFLTLGFLFAGFNKLRSKKA"
     gene            complement(35807..36376)
                     /locus_tag="PC494_000317"
     CDS             complement(35807..36376)
                     /locus_tag="PC494_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RnfABCDGE type electron transport complex
                     subunit G"
                     /protein_id="HDF3910849.1"
                     /translation="MNSMVRLGGTLLAISAIAALALGATNQVTAPVIEQRNIQANNEL
                     RKAVLPEAKEFKEMKEDTYKGLGDGLIAEVYEGLDGSEVVGYTLKAKPSGYGGEIEVM
                     VGISSEGQVTGVDIGNMSETAGLGAKAKDDAFKGQYKGKTAEPLEVAKGSTTADNQIL
                     AISGATITSTAVTTGVNAAIDVFNSALNK"
     gene            complement(36376..37353)
                     /locus_tag="PC494_000318"
     CDS             complement(36376..37353)
                     /locus_tag="PC494_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RnfABCDGE type electron transport complex
                     subunit D"
                     /protein_id="HDF3910850.1"
                     /translation="MENKLIVSSSPHMRSNEDTSYIMKQVIIALLPAAVAGVYFFRLN
                     ALSAMFFCILGTVGTEFLYQKFTKQKSTIGDFSAVVTGLLLAFNVPASLPWWMCLVGG
                     IFAILVVKMVFGGIGCNFVNPALAARAFLLASFPVAMTAWTQPGVNWIGKNLDAVTTA
                     TPLSFLKNGAAGLADLSSNGISLADMMIGNIGGCIGETSAILLLLGGVYLMYKGIINY
                     VIPVFYIATVFILTFLLGGFNITFAIYQLFAGGLMLGGFFMLTDYTTSPMTKKGQIIY
                     AVLAGLITTVIRMYGGYPEGVSYSILLVNCLAPLIDKFVRNRVFGEVAK"
     gene            complement(37376..38713)
                     /gene="rsxC"
                     /locus_tag="PC494_000319"
     CDS             complement(37376..38713)
                     /gene="rsxC"
                     /locus_tag="PC494_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transport complex subunit RsxC"
                     /protein_id="HDF3910851.1"
                     /translation="MKLLTFKGGIHPPYRKEYSNTKALEKAQAPKIVYIPLQQHIGAP
                     AKPIVEVGDEVKFGQKIGEQQGFVSCNVHSSVSGKVIAIEQHEVPGGSAQCVVIENDF
                     KEELHESVQPKGQLEDLSKEDIVGIIKEAGIVGMGGATFPNHVKVSPPPDSKAEVVIL
                     NGAECEPYLTADHRLMVENPEDVVFGLRALMKVLDVKKGFIGIETNKPDAIEAIQNVA
                     KDYSEIEVVGLQVKYPQGAEKQLIYACTGKEVPSGGLPIAAGAVVDNVATAAQIAKSI
                     KTGMPLVERITTITGSCIKEPKNLITKVGTLVSEIIEQCGGFKEDKKIGKVIMGGPMM
                     GIAQYTTEIATNKGSSGILCLDEEESRTPDIQNCLRCGRCTDVCPSFLQPLFISAYSL
                     KDDYDTAEYHRAMDCIECGSCSFICPARRPLLQSIRSAKREIGAKRRKQAAQK"
     gene            complement(38929..39873)
                     /locus_tag="PC494_000320"
     CDS             complement(38929..39873)
                     /locus_tag="PC494_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3910852.1"
                     /translation="MNRRKTIYRGFNNNRHKIDLRKYVITIACLCLIGYYSYTKIKDS
                     KILEYVSAKIPFLNNSSDITYKDISDELNSIKKGKKSKSQTNSDDKQETNPEKAVNNT
                     KEPEEVKLATIEGWDMYTIQVAAIDNNDDLKKIQTSLVNNDIPFSVMEKDGVKKIQTY
                     SSFDENDVRKQISSVRKVFPDAFLSHLDAPMLSLEYTSNYAYIESISKELNKLITNFK
                     EESSFWSNAENNVDMEKYNTILTNRKAISQNISKEAEKIDYSEMRLFKDNLIEYVKNV
                     NEKIDTASKAANEEKYSVSKSLLLSSMQEYSMFINSIK"
     gene            complement(39984..41258)
                     /locus_tag="PC494_000321"
     CDS             complement(39984..41258)
                     /locus_tag="PC494_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SH3 domain-containing protein"
                     /protein_id="HDF3910853.1"
                     /translation="MKKAIAALGIGAVAVSVSSINASALEKGTVTASALNIRSGPSSD
                     CDKVAKLYKGKTVEILEKSNGWYKVRVSSSVVGWGSAKYISTSGSSEGTSSQNNPTSS
                     GTTISGNGKVNVSSRLNVRSGAGTNYSLVGKANNGDIVKLLEQSNGWYKIKLSNGVTG
                     WASSQYISKTSEDVGTNNSSNSNSTNNSDKKPSSEESIEGKNGKVTSAVSLNVRSGPG
                     TSYSIIGKLNGGDVVELKAKSNGWYKVKLSSGTIGWVSASYISETNEGTKEKPNSSSN
                     QNSQPNSNSKPSFTGNSDKSTAKGSTIVDFAYTLIGIPYQWGASGPDKFDCSGFTQYV
                     FKHSVGVSIPRVSREQANFGSAISMGNYAPGDLVYFDTDGDGTTNHVGIYVGNSKFIH
                     CSGTQTNPNKVKVDNLTSSYWSKVLLGARRFV"
     gene            complement(41390..41761)
                     /locus_tag="PC494_000322"
     CDS             complement(41390..41761)
                     /locus_tag="PC494_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HDF3910854.1"
                     /translation="MKFNFCHNNFNVTNLEKSLDFYKKALGLKEVKRKEAEDGSFILV
                     YLGDGITSHTLELTWLRDWDRPYNLGDNEFHLALEVEEFDEAKKLHKDLDCICFENES
                     MGIYFIADPDNYWIEILPKNH"
     gene            complement(41989..42588)
                     /locus_tag="PC494_000323"
     CDS             complement(41989..42588)
                     /locus_tag="PC494_000323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3910855.1"
                     /translation="MESRGYKEDLKKMILDMAHKELESYVSQKGAKKYFEGNLDKIIN
                     NNIKKFNQSIGLNRVYLKMLKKCAYQESVTSISRTIKKEALFKSKKELFAFSEYLKLD
                     INKRLSYNQILRKISRYIYYNRSSYAQKYVVFKRGDEEYLLEPEKIKDELISSYRSKT
                     REDMRSIAKLLDIEVEDDYNAEDIRKKVINYIIKEKLKS"
     gene            complement(42789..43001)
                     /locus_tag="PC494_000324"
     CDS             complement(42789..43001)
                     /locus_tag="PC494_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy-metal-associated domain-containing
                     protein"
                     /protein_id="HDF3910856.1"
                     /translation="MKKKLLVEGMSCGHCVNHLKTALTEDIDGIEVLDVDLENKCASV
                     DMKDDVSIEKLKEVIAELGFELKGIE"
     gene            complement(43074..44789)
                     /locus_tag="PC494_000325"
     CDS             complement(43074..44789)
                     /locus_tag="PC494_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDF3910857.1"
                     /translation="MKRIKVLTVVLAITLMVAGCSNTKTKQSSSDSSLQSQSSIDAKY
                     INLTMVTPKTINPITNTDKSVGYIMNLVYDSLFTIDENYNVIPQLVKEYNIAQDGMSI
                     DIKLKDAKWHDGKNVTSNDVNYTIGLIQKSADSPYNEFTKNIASVNIKSDKDFTIKFK
                     ARYAFSIDSLIFPIVSQNHLDSKDVNDKNNNMIGNGKYKIESYTEREGMVLSVNKDYY
                     EEVPKTMKNIKVGMVPNEDARTSMVMALDSDITNVTLNDLSKFQEKEFNITKYQGRDY
                     ECVLFNYNNPFFKDVNFRKAIAHSIDKDRIISEGYMDDATPVNFPLNSKSKYYNSEMK
                     DLEFNKDKAIECLAKVEYANVNSVNQNDNKVKNQKKSAKKNSKKLTPEEEAKAKKAEE
                     DRIKKEAEEKKNREKEEVKKSLSEMNLKIIVNRDNSERIKTANIINENLKAIGINSTV
                     NQLSDKDMENALNSKNYDLALVGWKLSIIPDASSIIASSGYTDDKLNGYMSALTSSTS
                     EIETKKAYKDVQTYIKDNATFISLAVRNNYIVSNSRLKGKITPNDFDVYEGISNLDIK
                     SNESN"
     gene            complement(44789..45343)
                     /locus_tag="PC494_000326"
     CDS             complement(44789..45343)
                     /locus_tag="PC494_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic transglycosylase domain-containing
                     protein"
                     /protein_id="HDF3910858.1"
                     /translation="MNSKKVLILSIFIILFGALLMESKVIHKFLYPKKYSEYVEKYSK
                     EFNLDENIVYSVIKAESKFNSSAVSKKEAKGLMQILDITRDWGAEELNLKNVDIFDPE
                     TNIRLGCWYLSKLYKEFGKLDLVIAAYNGGSGNVKKWLENNEYSKDGENLHDIPFKQT
                     SKYVEKVKNNYEHYNKIYGKKGKN"
     gene            complement(45336..45938)
                     /locus_tag="PC494_000327"
     CDS             complement(45336..45938)
                     /locus_tag="PC494_000327"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HDF3910859.1"
                     /translation="MLILGLTGGIGCGKSSLSNIFRNLNIPIVDADIISRKIFEDKLL
                     LEKVFVHFGQSIKNDDGTLNRKALGKIVFSDEEKLKELNNLTHPRIREKIISEIEKLR
                     KKGENIVVLDAAILVESGFLDMVDKLLVVTCKQEVQISRIQKRDNCSEQEALSRINSQ
                     MSQEEKSKYGDYIIDNSGTITELESKAHKFIEYMKENWRE"
     gene            complement(45947..48595)
                     /gene="polA"
                     /locus_tag="PC494_000328"
     CDS             complement(45947..48595)
                     /gene="polA"
                     /locus_tag="PC494_000328"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HDF3910860.1"
                     /translation="MEKKLIIIDGNSIINRAFYALPEMNNKEGLKTNAIYGFTTMLFK
                     MIDIYKPTHISVAFDRKAPTFRHLEYKDYKAGRKGMPDELAEQLQPLKDLLDKFRINR
                     LEIDGYEADDIIGTVSKKAEENGYKVYIVTGDKDAIQLASDNTTTLITKKGVGEVEEY
                     NFNSVIEKYEMTPTQFIDLKGLMGDKSDNIPGVPGIGEKTGIKLIKEFSSIENLIENT
                     DKLKGSVKKKIEENKEIAIQSKRLATIIRDVPIEVDLDSMIFGDYDKDELLDKFRYFG
                     FTSLLSRLVDLVDSDDTEHVEEKIEILKLKDIEKFIDEVNKKGQVILKTVRGQGNILE
                     KNIIYIFISVDGEKIYYVDSNEVSKLDSIFSNNEIKKYGYNLKDDYISLKPYNINLEN
                     MYFDITIAEYLIDSTSSTSYDCSAIAMKYLSKKVKSKEELLGKGVKSKNYEDLEFEDL
                     AEYMGQIICTVKETVPMMERSLMDMSMDGLFYHVEMPLVEVLGHMEYEGIKVDKSILD
                     ELSVEFKEIIATLEKEIYELSGEPFNINSPKQLGVILFEKLELPIIKKTKTGYSTNAD
                     VLEKLRDKHPIIDKITEYRQIVKLNSTYVEGLLNIINPESNRIHSSFNQTITTTGRIS
                     STEPNLQNIPIKMEMGRKIRKVFIADDNCKLVDADYSQVELRVLAHMSQDENMIEAFK
                     HHEDIHTKTASQVFNVPMEDVTSELRGAAKAVNFGIIYGKSDFGLADDLNIPVPKAKE
                     YIESYFAKYHKIKEFMDTTVEKASEDGYAVTILNRRRYIPEIKSSNFMERNRGKRFAM
                     NAPIQGSAADIIKIAMINVHKKLEENNLKSKLILQVHDELIVEAIDDEIDIVKKIVKE
                     EMENAVNMDVHLDVDLNVGSSWYETK"
     gene            48747..48834
                     /locus_tag="PC494_000329"
     tRNA            48747..48834
                     /locus_tag="PC494_000329"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:48781..48783,aa:Leu,seq:caa)
     gene            complement(49021..49464)
                     /locus_tag="PC494_000330"
     CDS             complement(49021..49464)
                     /locus_tag="PC494_000330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3910861.1"
                     /translation="MKKNMLYVGIIYFICGILLVLLATFTEFSFEAFIWGLSGAALGP
                     GVCMILQYMYWSKPERAVDYEEKIKNQRIEMNDERRIMLRDKAGRITNQIMCYVLVIL
                     IFIVSILSVFSVMVISKWVLVVLGLLILFQFICSVVVYNKLDKRL"
     gene            complement(49467..49664)
                     /locus_tag="PC494_000331"
     CDS             complement(49467..49664)
                     /locus_tag="PC494_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004631111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF3910862.1"
                     /translation="MKNRLEEIRKERGIKQEELASILQVSRQTIGSLENGRYNPSIIL
                     AFKIARYFDMSIEEIFIYEEE"
     gene            complement(49856..50722)
                     /locus_tag="PC494_000332"
     CDS             complement(49856..50722)
                     /locus_tag="PC494_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HDF3910863.1"
                     /translation="MEWINKLNQAITYIEENLESGVDYAEAAKIACCSTFHFQRMFSY
                     IAEVPLSEYIRRRRMTKAAFELQNSNIKILELSEKYGYDSPTSFNRAFQNIHNISPSA
                     ARAKGVVLKAYPKMTLSIYVKGNIEMQYRIVEKKGFRIVGIKESMNMIVEECFEKVPK
                     LWAKCIKNGTIDKLSELINNEPCGLLGVSVCTNSKGLDYYIAAPTDKPVLEDTHEYLI
                     PSGTWAVFECVSPMPNALAIQELQKRIITEWLPSSGYVYANLPDIELYPNGDINAPDY
                     TTEVWIPIQKPS"
     gene            complement(50948..51817)
                     /locus_tag="PC494_000333"
     CDS             complement(50948..51817)
                     /locus_tag="PC494_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HDF3910864.1"
                     /translation="MDYKTIILNRKSVREYKNTDIKEEYLSEIKKYSESCKKLVPEID
                     VDVRIMNRSEVFNNLDKVAGYKGNMIDSPSYIIILSDIKDNYIENSGYIGESIIFKVT
                     ELGIGSCWVTFEDGKKVKEKLGINSDKEVTGIIAIGYGENVSNAKVLNATKTGQNYSK
                     SDMQVVTDKGSTRLGVEDVVYMNEWGNVASIEILEERALLDAFHYARLAPSTLNRQPW
                     RFIVDGGTVVLAVRKDGHTNLYEEKIDIGIVMLYFATIISATMFDLKWNLGTPDKDYK
                     VPEDYKIVGYCNI"
     gene            complement(52323..52544)
                     /locus_tag="PC494_000334"
     CDS             complement(52323..52544)
                     /locus_tag="PC494_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3910865.1"
                     /translation="MNVNNHKCPECGEHSKKFEIVEENEDCVIFECYTCGTISILKYC
                     ENCKEFVFVNIPNNVETYEYCCGKCNNKI"
     gene            complement(53046..54026)
                     /locus_tag="PC494_000335"
     CDS             complement(53046..54026)
                     /locus_tag="PC494_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3910866.1"
                     /translation="MGDTSRFYESVKNKYPKLKDGTRVHLWPKENIIIGPIYDEEDGY
                     KKSIGNVDSLSWKQIVILAECDGKNTTDDIINILSNRYRNIHNMKEKVMEFFMFYENV
                     YLTFEDDIQTLSSVFEITGNKSYITPLYFTIEIDGDNNTNDYFSEITSLLNCMYEKGC
                     RFIEVIGEDILKNKSMREIFQYMLDHFDLIVVTKDSFTIDRSLIKELDNYRHKVIWKV
                     YSKNDDTRIKLKEDIKITSLIKRGHTVVRGDREKAIKIEDMRFKDTKERFSKYGAEWS
                     HLYISSDGSVKSYSFQKDKRIYLGNIFNNSVEEIFLEMQNKIDKLEIVYQ"
     gene            complement(54190..55062)
                     /locus_tag="PC494_000336"
     CDS             complement(54190..55062)
                     /locus_tag="PC494_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HDF3910867.1"
                     /translation="MIIKVSMTVLVLILLYILYKYETQHIETTEYTIFNKKIPKEFDN
                     FKIVQVSDLHNKVFDKNNKVLIDKIESLNPDVIFITGDLVDGENKNFQVALDLIDNLV
                     EKYEVYHIIGNHEQKSLIKKYKHLYKDYFKELYSKKIINMENESVRIYRGNSHLNLYG
                     LIIPLECYPYLFANNKKLELSDNFVEDNLGKVNENEYNILLAHTPFFFEKYAKWGADL
                     VLAGHVHGGIIRIPFVGGVLSPNREFFPKYDWGKYEKDNSTMILNKGLGGSKVLIRLN
                     CKPEIVKITFKYEK"
     gene            complement(55226..55777)
                     /locus_tag="PC494_000337"
     CDS             complement(55226..55777)
                     /locus_tag="PC494_000337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF3910868.1"
                     /translation="MDNKFPNVGENLRLLRQEMGISLDKASKMTGVSKAMLGQIERGE
                     SSPTVSTLWKISSGFKINFTTLLNENTNTYEVIKKEEVEPIVEQKGNMKLYPIYPFSP
                     QRRFELFIIELEENCTHVSSTHSHVLEEYVLVIEGKLDLNVDGKTYILESGHSIRFDG
                     TLEHIYKNLNKGKTIFHNIEVYR"
     gene            complement(55797..56699)
                     /locus_tag="PC494_000338"
     CDS             complement(55797..56699)
                     /locus_tag="PC494_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl-radical enzyme activating protein"
                     /protein_id="HDF3910869.1"
                     /translation="MSKKGRVVKVQHFSVNDGDGIRTTIFLEGCKLKCKWCSNPDSWS
                     NIVKLGVMKDKCVSCNRCIDVCPQNISSLFDRAQINNKCDLCGECIKVCLKDAICIMT
                     EEMSVEEIVEEVEKDFIFFFESNGGITFSGGEPTLQIDFLRELVDIFYDKGINIAIET
                     CGYFDWNKVNDVFEKIDHIFVDIKSMDDNIHKEYTGVSNKIILDNICRLSKLNKSMVI
                     RVPIIYGVNDSEENIRNTALFVKQNVPGGKMELLPYHKFGIDKYKALGLEDYIYEFDE
                     ICNNHMLKLKEIVELTGVKIIEYK"
     gene            complement(56714..59086)
                     /locus_tag="PC494_000339"
     CDS             complement(56714..59086)
                     /locus_tag="PC494_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase/glycerol dehydratase
                     family glycyl radical enzyme"
                     /protein_id="HDF3910870.1"
                     /translation="MSQTNRIEAFRQEYINSKPMICCERARIFTESHKKTEGEAICIR
                     RAKAFLETCKELPIKIFENELIVGTAGKFRRTGILTPEFSWQWVDKEMDTFDKRTQDP
                     YVISKEQIEFIRKEIFPYWKGKSLEEVFLARIPEDTAKILVDTGIIDNDSKWRQAVGE
                     VTPDYQDILFVKGYKGIKEDADKKIKELDISVSENIEKIDFYKSVSIVAQGIMTLAQR
                     YSNLAKEMSKQETDEKRKLELIKISEICMNVPANPPTNFYEAIQFVWFVQLGGILSEN
                     PLALNLGRFDQYMYPYYENDAREGKITESEAQELIEALWIKLSEWVWTISANTANYFA
                     GYNQFQNLTVGGKKRNGTDGTNDISYMCLKATESVKTHQPGLSVRVSQGAPDNFVMAV
                     AKLVKQGTGFPAIHSDSAGAQMLLQDGYDAEDARDWSNCGCVVPHFRKTGQWTSAVNI
                     NFAAALEYAMNEGKSRLTGEKMGLDTKNITEFTSFEELKDEFLKQLAYLVKSSVIGTT
                     VAQQIHKEMVPRPFLSTCVDGCLDKGVDLSKGGAKYNIGPVLTGIGLGVVSNSLAAIK
                     KLVFEDKVTTLEELTKALNNDWEGYEELRKLALDVPKYGNDNDYVDSLAIEVSDFYYT
                     ETRKYKDIFGSKFNSAFMGISNYVPTGKIVGATPCGRKATKPLTEGVSPFVGTDTTSP
                     LAAMKSASKINHDVHTGGTLLNLRLNQDLVETERGLRNLTSMIKSYFALGGFHVQFNT
                     ISNDTLLKAQENPEEYKDLLVRVAGYSTQFVNLSREMQDAIIARNSHSNF"
     gene            complement(59307..59996)
                     /locus_tag="PC494_000340"
     CDS             complement(59307..59996)
                     /locus_tag="PC494_000340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HDF3910871.1"
                     /translation="MKVKRNINRVAIIVALNLSLALMVGCMSPVSDKNLSSSEQISKD
                     SLKEQVEDKKDESIELFNNYSQKINDAKGREEVKKDLSQRFSKAIIDSGYSITNSKSD
                     GSFVVSINGAEKPPEKNIRSLFYSMSEDDKEGKVTIDILCAKEYPEDDKLSESDKYVK
                     FIYNLFKSLTDTNLTEKEIFSMVEEDFNKGVGVVELPYMKDIHVEVNKVKQSTKVLKL
                     SLVYKFDISNH"
     gene            complement(60237..61616)
                     /locus_tag="PC494_000341"
     CDS             complement(60237..61616)
                     /locus_tag="PC494_000341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HDF3910872.1"
                     /translation="MLNFMTELLVVLSIFIQFSIMNGILIYKKDSKKNEKIVFYIVLF
                     LIYIIIQISRLFNGGNYFSNINYLFYILAFIAWGGYYNYFYKMGYIKYSIFFYLFSVY
                     YKCLDAVIYRILFFAITGNVISSKESLLVPYLESIKIQIYSNLIIILIYLIFSFFRKS
                     IKLISQDKRNYVYLLFALLVNTMNMLVNYVLKKLERFGSLHSEGYYFDNFVNPKLVGA
                     SSIFLILLFKEIIKENRLKSQAELIKNKLDMQYAHYLSIQESHMRVKKLYHDINNHIY
                     CIDNLRNNSKEINEYVNNLKDEIKTFKYIYNTGNMILDIIINEKSEVCLKKGIKFTCS
                     INFSKVNFVKPIDVSSIFSNILDNAIEACDKIVDENINKYIRIKGTITRSFFVLKCEN
                     SKLNQLTFNKNILLTNKMDKFVHGIGIQSIKSSLQKYNGELLFENSIDKFILNIYIPL
                     DQDTDSWGD"
     gene            complement(61610..62323)
                     /gene="rgbR"
                     /locus_tag="PC494_000342"
     CDS             complement(61610..62323)
                     /gene="rgbR"
                     /locus_tag="PC494_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator RgbR"
                     /protein_id="HDF3910873.1"
                     /translation="MIKIAVCEDEKETQLLIEDYLENILKDISIEYEIQKYISGEELL
                     ESNLKDIDILLLDIKMEKLNGMDTARKIREVDNEMEIIFVTSLIDYVQEGYEVRAYRY
                     LLKPIELEELKKHVLTCIKDIEINKESHITIKNKSNTYKIYLNEIKYIEVQKKDMLIH
                     TINKNFDIKYSLGKIEKELNPYKFIRCHKSFIVNLRYVENIKPNTAILESGEEVPISR
                     YRYKEVKEKFLKFLGDTIC"
     gene            complement(62573..63133)
                     /locus_tag="PC494_000343"
     CDS             complement(62573..63133)
                     /locus_tag="PC494_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2812 domain-containing protein"
                     /protein_id="HDF3910874.1"
                     /translation="MSAMEKKIKFKFDWYSSPDKIEKWLEDIEAKGYNLYKINKFGGI
                     FYFHKGSPRKIKYTVDYYYDVENNYFDEHKSNGWNLVFRSIGSFMGTSAWYIWSKEYK
                     DIPPKLYSDSDKTNKVKSILFMNMFIFFMLVVIFIYLLNIEIRNLYSGYGASVTAIVL
                     QIILLILYAVQLYRRLMYYLRLKKFK"
     gene            complement(63228..64031)
                     /gene="zupT"
                     /locus_tag="PC494_000344"
     CDS             complement(63228..64031)
                     /gene="zupT"
                     /locus_tag="PC494_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc transporter ZupT"
                     /protein_id="HDF3910875.1"
                     /translation="MNNVIFAFLITLLAGLSTGIGSCIAFFAKKTNTKFLSISLGFSA
                     GVMIYVSMIEIFPKAQDALTKSMGEKLGSWSTVIAFFIGMAIIAVIDKLIPQEENPHE
                     IKKMENIEEKNIKKNKSLLRTGIFTAMAIAIHNFPEGLATFISALDDVTIAIPIAIAI
                     AIHNIPEGISVSVPVYYATGDKKKAFYYSFLSGMSEPLGAIIGYVLLRNFLNDITLGI
                     VFAIVGGIMVFISLDELLPSAREYGEHHLSIYGLIAGMGVMAISLLLFK"
     gene            complement(64182..65345)
                     /locus_tag="PC494_000345"
     CDS             complement(64182..65345)
                     /locus_tag="PC494_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HDF3910876.1"
                     /translation="MDIKEITKSYKDYVIKLRREFHENPEKSMEEVRTSKRVKEELDK
                     IGIPYVSAGGTGVIATIKGANPGKTVALRGDMDALQVVECTDVEYKSKNEGLMHACGH
                     DGHTSMLLGAAKVLNDIKDSINGTVKLFFQPGEEVGKGARAMIQDGAMEGVDSVFGIH
                     LWTDVESGTISVEEGPRMASADFFKITVKGRGGHGSLPHQGVDAVLASSAIVMNLQSM
                     VSREVSPLEPLVVSVGVLNSGTRFNVIASEAILEGTIRLFNPELRKQIPRILERIAKS
                     TAEAYRADAELEYGYLTPAVINDKECSKIATDAAIKLFGEDCITLFEKVTGAEDLAEF
                     MNIAPGALAFVGARNESKGACYPHHHGCFNIDEDALEIGTALYVQYAVDFLNK"
     gene            complement(65405..66592)
                     /locus_tag="PC494_000346"
     CDS             complement(65405..66592)
                     /locus_tag="PC494_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3910877.1"
                     /translation="MEAITAFCLVLVSLTIGDIVSAKTKAFVPSVFVSAIIFIVGFWT
                     FFPENIVDLAALGTPLAQLGMLLLITHMGTMMSIKELAGQWKTIVIALAGIVGICVGA
                     LALGTVVFGWDTAVIATPPLTGGLVASIMMADAATAKGLASLSVLAILMYVAQGFAGY
                     PITALMLKKEGKRLLSDFRSGKVTVNTDEEKVKDLPEQKSRFKIIPDLPEKYDTTYMI
                     ILRLGFVAWLAVQFTNLTNEVVSRYVICLIFGVIASELGIVDRKPLNKSGSFGWLMTS
                     LMAFIFAGLAKATPAMLVEMAVPLVGIIIFGVIGMGIFSIIVGKLLGESKEMAFSVSL
                     TSLYGFPPNYILTEEAVKALAETPEEKEFLMDKMLPKMLVGGFTTVTIASVVIAGIFV
                     NLI"
     gene            complement(66955..68655)
                     /locus_tag="PC494_000347"
     CDS             complement(66955..68655)
                     /locus_tag="PC494_000347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF3910878.1"
                     /translation="MIKQFVKYYKPYKKIFTLDLIAAFLFSLCDLVYPMITRNIMDDV
                     VPNKNLRMLVVFAVALILIFIAKAGLNYFMQYWGHVIGVDMQADMRNEVFTHLQRLPN
                     TYFDNNKSGVTMSRIVNDLMDITELAHHGPEDLFISIVMLVGSFFILIDINIPLTLII
                     FAILPFIIWFAIAKKDKMNIAFMKSRVTIGDVNATLENSIAGMKVTKSFCTEKEELNK
                     FVRSNKLFRRARQDSYKVMAEYYSGMNLYMDILEWVVVIAGGYFTYIGKITLGDFAAY
                     ILYVKMFIQPMKKLINFTEQYQNGMTGFKRFIEIMEQDHQKEAKNPIELENVKGDIEI
                     ENISFTYEDKTQVLDNLSLSIKAGKTIALVGPSGGGKTTLCNLLPRFYEFDKGDIKID
                     GKSIKDVSLKSLRKNIGIVQQDVFLFTGTIRDNILCGNPNATDEEMIAAAKKARIHDF
                     VETLPDGYDTYIGERGVKLSGGQKQRISISRIFLKNPPIIILDEATSALDNVTEREIQ
                     ESLEELSKDRTNLVVAHRLTTIKNADEIIVLTDKGIEERGTHEELVNKNGVYSRLHNN
                     "
     gene            complement(68910..69185)
                     /locus_tag="PC494_000348"
     CDS             complement(68910..69185)
                     /locus_tag="PC494_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDF3910879.1"
                     /translation="MKKILVACGAGIATSTIVCDRVERLVKENNIQAEVEQCKIAECS
                     TKQEGADLIVSTTILPTTYDIPTIKATGYITGINTTALDKKILNALK"
     gene            complement(69304..69876)
                     /gene="mobB"
                     /locus_tag="PC494_000349"
     CDS             complement(69304..69876)
                     /gene="mobB"
                     /locus_tag="PC494_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-guanine dinucleotide biosynthesis
                     protein B"
                     /protein_id="HDF3910880.1"
                     /translation="MLLLDSFMKGHNFMYNILSVVSYSGVGKTTLIEGIIKELNKKGY
                     RVGVIKHTCHDFDMDEEGKDTYKHRKSGARKVCIISDKRVAYIEELKEKNPLYKMIQL
                     YEDMDLIIIEGYKNYRFKRLEVTRKGKYEDILSNKSDLIGIVSDIEYKLNIEQFNLND
                     YKNISKYIESCIKNEILSISNVEIKNILKE"
     gene            complement(69860..71041)
                     /locus_tag="PC494_000350"
     CDS             complement(69860..71041)
                     /locus_tag="PC494_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin molybdotransferase MoeA"
                     /protein_id="HDF3910881.1"
                     /translation="MIELEDAIKIIEKNVLPINRVKIVNLIDAVNKVVAEDIYSTIDS
                     PPFDRSPYDGYAYNANSENRNLKVIGTLYAGDVFNRVLNKNEAVKIMTGGKIPQGANC
                     VIKKEDVTVIGDMITLNIKLKEYDNYIFKGEDIKKGQLIINKNQNIGYDGIGVLASLG
                     ISKVTVYDDLKVGILNTGTELQDINETLENGKIYDSNRYTLYSRLLKLGIQADTICNC
                     SDDILDLEKKVKNMLQSVDFLITTGGVSVGDKDLIPDVFKKIGATELFWKINIKPGGA
                     CYVGTLGEKLLFGLSGNPHAAIVVFDNVIVPVIEYLTYKKGTHHIKAIFKGEFNKLSN
                     KDRFVSGKLYTSEGKLYVELNDKKDAKARLSATLRSNCMIKIKKNETIKENQLVDVVI
                     R"
     gene            complement(71252..71986)
                     /locus_tag="PC494_000351"
     CDS             complement(71252..71986)
                     /locus_tag="PC494_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3910882.1"
                     /translation="MKLKRSLVCVTILGIILVGCHKENTKEKNQVASKATQQKTMTKV
                     QNDVNEIMNKDYKYIIKNMGIPYNTFYYIKPKVLKESNTMQDINTSSYMTLVYPKYTG
                     NDELDGSALYVDINENKVVNVETNSFSSQGISVIDAESSIVIEKSDHEKSAVSLENFR
                     HIDLGEYVGVEDSRINEIVGDANYDLTAYNHEGSKVVKSYRLKEDNKILKKEVLTISI
                     VDNKIKSIKTIESDKIVKIIKGTLLE"
     gene            72348..73253
                     /locus_tag="PC494_000352"
     CDS             72348..73253
                     /locus_tag="PC494_000352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDF3910883.1"
                     /translation="MDFKQLEVFVAVAKHQSFSKAARELFLTQPTVSAHIQNLERELE
                     TVLINRSNKVITLTKSGEILYEHAIYILNNCKRAIYDIKEYSGKIEGIIDIACSSIPE
                     TYILPDFMKSFSMSYPDVKFSISHYDSQYAISEILNERISFGLVGSKINNPQIEYLDL
                     LDDELVLITPSDFKIDNKNNCIDIGELAYLNFIMRKEGSGTRNLILNTLSKNNFPVSK
                     LNVIAHVESNEAIKEMVRLGLGVSFISYISAIDYLNAGKIKCYKIKDVDFTRKFFFIY
                     SKKKTFSPLEDKFLNRLCEYFEIII"
     gene            complement(73413..74255)
                     /locus_tag="PC494_000353"
     CDS             complement(73413..74255)
                     /locus_tag="PC494_000353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HDF3910884.1"
                     /translation="MTTSSKKLETISPDSKITRKDFWKCFRRSLTLDSSWNYERMQNI
                     AYAYMMAPIIRRLYKDDKEKKSKALKRHLEFMSVTPHISTLLVGISGAMEEENAKNKE
                     FDANSINAVKSSLMGPVSGIGDSFFWGTLKLIAAGVGIALASQGNIMGPILFLLIINV
                     PHFIIRYICLDKGFKYGTQFFKDVSGSSIVSKVMEAASMLGLMVIGGMTASNVMLKLS
                     VNVGSGEWAEPIQTYLDQIMPCMLPAMIFGIMYWLLGKKVKTTTILISVMIICIVLAA
                     IGVV"
     gene            complement(74239..74997)
                     /locus_tag="PC494_000354"
     CDS             complement(74239..74997)
                     /locus_tag="PC494_000354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDF3910885.1"
                     /translation="MEFTQVILITLIAFFAYMHSFVGSTMHNRPIVVAPLVGLALGNL
                     HTGIVIGSTLELVFMGAFPVGASNPPDFVSGSIIATAFVILTGQDVSAAVVLAVPIAT
                     LVLLIDNFLMTVVLTWGAHIADRYAEEGNIEGVERVQLLFGIGNKLILAIIVGIGFSL
                     GVPVIEKILSFIPSYVTHGMDVAAGVIPAIGFAMLARMMLNKKTVAFLLLGFILVAYL
                     NITVTGVALFGLAIALIYVNFVGEKEVIVDDNEF"
     gene            complement(75014..75484)
                     /locus_tag="PC494_000355"
     CDS             complement(75014..75484)
                     /locus_tag="PC494_000355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDF3910886.1"
                     /translation="MIKLVRVDHRLIHGQVAFTWTKFLSTDCILIASDDLLKDELRMA
                     GLKMAKPSNVKLVMKSIADSIKALNSGVTDKYNLLILCESVEDVYRLAKEVKAIKSIN
                     LGGTKSDDNRENISKAVHVSKDDIKMIKELDSEGVNVFVQLVPDDDATNVMKLI"
     gene            complement(75484..76227)
                     /locus_tag="PC494_000356"
     CDS             complement(75484..76227)
                     /locus_tag="PC494_000356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane biogenesis protein"
                     /protein_id="HDF3910887.1"
                     /translation="MKKKGILSVFKSKKPIIAMIHLKGDTPEDIFERAKKEITIFEEN
                     GVDGIMLENYYGNYYDLERILEYVSKANLSIPYGVNCLNVDTMGFELATKYNASYIQV
                     DSVVGHVKPRDEATLEEFFKLQRSKCPAYLIGGVRFKYQPVLSENDVEEDLKIGMTRC
                     DAIAVTENATGQETSMEKIELFRKNLGDFPLVIAAGVTLENAKKQLKLGDMAIIGSYF
                     KDNYKDFGDVSVEHVKTFMDEIKKIREEL"
     gene            complement(76231..76644)
                     /locus_tag="PC494_000357"
     CDS             complement(76231..76644)
                     /locus_tag="PC494_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDF3910888.1"
                     /translation="MKKIILASHGDFSKGLLNAVKMIVGDLADCVSSYGLYPGQSASD
                     FALELEKTISEDKECEYIILSDLYGASVCTAMLRLTNLHNVRLFSGMNLNMVLELLTR
                     FSDELTVEDIDQLVEESRRGIQSVTLQIKEEEEVF"
     gene            complement(76670..77422)
                     /locus_tag="PC494_000358"
     CDS             complement(76670..77422)
                     /locus_tag="PC494_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDF3910889.1"
                     /translation="MDEKRQKKEMDLEVNSFVPLYQQLYDNIKKQIASGIYKPGDKLP
                     SEGDLCKEFNISRITVRNALNELVKEDILCKKRGKGTYVTIPERIEATCAGNSFTNSC
                     HRINAKPSTKIISVLIKKADKQVAEALSIELEEKVICIKRLRLIDEVPVIFEVDYFRI
                     DYMFLLKEELEDKSLMEVISNNISTLPKRVENIFEVKHSNKEYSDHLKCASNMPLLKV
                     RQSVYTENNDVLYYNEQFIRSDKYKYAVSAEI"
     gene            complement(77662..79056)
                     /locus_tag="PC494_000359"
     CDS             complement(77662..79056)
                     /locus_tag="PC494_000359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HDF3910890.1"
                     /translation="MNLKYEFKNAWDFERKENTIEQIMQYSRNYMEFLSKSKTERLSV
                     KEIIKLAKENNYISIDEAMEKGSISCGDKIYVINKEKAVALFVIGKNYIEKGMKIIGS
                     HIDSPRLDLKPNPLYQESNLGFFKTHYYGGIKKYQWTAIPLALHGIVILNDGTKVDIS
                     IGEEDSDPVFCVTDLLIHLAGDQMQKKLSEGISGEALNILIGNIPLEDEEKEPITANI
                     LKILNEKYNIVEEDLLSAEIEVVPAGKARDLGLDRSMVLGYGHDDRVCSYAAVKAILE
                     TEQPEFTSVALCVDKEEIGSKGNTGMHSKFFENTVAELIALEGDYCDIKVRRALANSK
                     VLSADVSAGYDPNFGEAYEKRNSAYMGNGVVLTKYTGSRGKSGCNDANAEFMSEVKRI
                     FNKGNVVWQTAELGKVDQGGGGTIAHILANQGAEVIDCGVGVLNMHAPHEIVSKVDIY
                     EMYKGYKAFFNINL"
     gene            complement(79076..79285)
                     /locus_tag="PC494_000360"
     CDS             complement(79076..79285)
                     /locus_tag="PC494_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 domain-containing protein"
                     /protein_id="HDF3910891.1"
                     /translation="MFDKKKLDRINELAKKNKEGILSADEIKEREILRKEYLENFRAH
                     FRSRLDSVKVVSPEEYEQYMKNNKN"
     gene            complement(79314..80759)
                     /locus_tag="PC494_000361"
     CDS             complement(79314..80759)
                     /locus_tag="PC494_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HDF3910892.1"
                     /translation="MEKYRIDLNEKKSTKYIQIFNHIKELIINKELVEHEKLPPIRKL
                     SNFLQVNNTTIVKVYELLENEGYVYKIIGSGTFVSSLNSYKSGIDNRKNKIIVQREDL
                     IHFDNGNPSNDMFPIDSFKNAVNMALSKDGSSIFEYDEGLGSEELREKMVEYLSDGNI
                     KTTKENIQIISGAQQGIDIVCKGLISYSDVVFMEEPSYNGAIEVFKSRGAKIISIPML
                     DDGIDIGILKLKLEKIKPRLIYIMPNFQNPTGISYSTYKKKKLIELAEEHDFYIIEDD
                     FISDFVFESKDNRTIRSYDDKNRVVYIKSFSKILMPGLRIGIVEMPNELLKKVLWAKY
                     SSDISTPGLIQKSMYYYMNNFDWKNYLSHIEKIYTDKYKLAKNLINDKLSGKLKVRKS
                     CGGINFFLELPRGYTSQAFTNFMLNKGVSMLPGTYFFDNLVDDRFFRINIARPSMEEL
                     EKGISIISDNIDEFFCEYKNKLDIKSNKLFY"
     gene            80869..81663
                     /locus_tag="PC494_000362"
     CDS             80869..81663
                     /locus_tag="PC494_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphatase HisJ family protein"
                     /protein_id="HDF3910893.1"
                     /translation="MFYDYHMHSSFSTDGKSTMEQMVKKSIELGLEEICFTDHVDYDV
                     YADDSFSIVYEDYFKSLETLQSKYKDKISIKKGIEFGVQTQLMDTYKKEAHQYPLDFI
                     ICSIHAIDTMDLYLGNYFKDKTQHEVYENYYLYLYNIVKNYKDYSVLGHLDLIKRYAP
                     YDTVLDDRLFSDIIEETLKQAIYDGKGIEINTSCYRYNLPDLTPSKYILQMYKDLGGE
                     IITTGSDSHHISQVACEFDYIYSLLKNMGFKYVSKFNKLKPEFIKL"
     gene            81714..83036
                     /locus_tag="PC494_000363"
     CDS             81714..83036
                     /locus_tag="PC494_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HDF3910894.1"
                     /translation="MKVPYLVLSTVILFISNFIVRIFGFLYKIFLSRALGETGLGIYH
                     MIFNFLMICLAVTTTGIPTALSCLVAKRKALNDRHNTNALFISTLYISFFVALIISIV
                     ASFNSSFLSLKFLKDAKLNLFILAVCPAIVIITLSNVLRGYYYGIKNVKIPAIGQIIE
                     QIGKILFVFLLVMYINNKSMNCYIALLGISIGELSNIIFMLICLWRDSSFDNRYIISI
                     KDFYNSSMETLKMSIPITCNRMSNILLQSISSMMIPSRLALSGMTYQQSLSMYGIVSG
                     MVMPFIFLPFTVGSALIVNLIPTISQEMALRKRKSVIKKIKYSILLTLFVGILSSIFF
                     YFFGKDLCILVFKNTLAGEYLKAMFLVPLFMSLNQTLSGILHSIRKELASSINTITGM
                     LIQLIALYVFLPIPGLNIYAYIYTMTIVSIFTCLLHTIVLFKSLKSIR"
     gene            complement(83136..84353)
                     /gene="cdeC"
                     /locus_tag="PC494_000364"
     CDS             complement(83136..84353)
                     /gene="cdeC"
                     /locus_tag="PC494_000364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exosporium morphogenetic protein CdeC"
                     /protein_id="HDF3910895.1"
                     /translation="MQDYKKNKRRMMNQPMSTMNEEEVYTDEINSEDMRGFKKSHHHN
                     GCNTDNKCECHDDCNPCNPCNPCKPNPCNPCKPNPCDDNCGCHDNCKCDCEPCEMDSD
                     ECFENKCGPECCNPISPRNFSVSNAVPFAIEANRIFDTMQFQTFTDATGPNGEPLTFE
                     TEVVEVFGSVPSAGQASVTIEKICLSNDGIVIDTGMTTLEDFDLDPLGDIVGRNCETT
                     FEFAVCGERNSECCRQGKGKSVAYKQRGLTVAVRNLVLELRGRCGCTEFVALAFPAVR
                     AGGGCKRRVDYVEFTFNTLSAPICLPADGRAVTLRQEYQTNLTVDCIGKSILKLECNE
                     CCEPFYELIIPNDIDLVLCLQETVSTLISEQIVVLASPNPIQPRLVDTFSKVCDFSQC
                     GPNHGSGKPSCHR"
     gene            complement(84536..84716)
                     /gene="ssrS"
                     /locus_tag="PC494_000365"
     ncRNA           complement(84536..84716)
                     /ncRNA_class="other"
                     /gene="ssrS"
                     /locus_tag="PC494_000365"
                     /product="6S RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00013"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00013"
     gene            complement(84831..85736)
                     /locus_tag="PC494_000366"
     CDS             complement(84831..85736)
                     /locus_tag="PC494_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3910896.1"
                     /translation="MNNLLFLIGVIALSNGNISIFDDKNKSKGNNRVRKNKKNANDKL
                     SQSTHGNLRFDANDIKRGLRLMDLSEEDLEMGMEIITRTKKYMSRDERKILIKIESVL
                     DLVRGIKKLNNIDMVDTEDETDFFRKMDSDDKKNMMIKEIIDVFPEKRKNSVEKAIGM
                     KKKIDLFAELFLPDDFGEGGFSLSSLANINNLGSMNNLKLLGSLLRGDDSNNDDEDNN
                     DELNYEDEELDCEDKELDDDELTDEGEMEDNEDELVEDKNTGYENIENDEDIVYDEEL
                     YNINEQESEYNYNEKNTKTRAKKKR"
     gene            85948..86346
                     /locus_tag="PC494_000367"
     CDS             85948..86346
                     /locus_tag="PC494_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3910897.1"
                     /translation="MKKLDTESLEKMAKQKNIDKDKIEKMADSYKGKSENELMEELIK
                     IGKNLDGRDEVVSKFKAFLDENQRKKLDNIMEKISDAENQRDTKPAKTKKAKPTKGKS
                     NSPAPKNTPGSQQKKSKSLFKKTKKSNPHE"
     gene            complement(86469..87485)
                     /gene="ccpA"
                     /locus_tag="PC494_000368"
     CDS             complement(86469..87485)
                     /gene="ccpA"
                     /locus_tag="PC494_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator CcpA"
                     /protein_id="HDF3910898.1"
                     /translation="MKGNITIKDVAKQAGVSISTVSRVINDSKPVTDEVKQKVLEVIK
                     ETGYIPNPLARSLVTKKSQLIGVIVPEVSDSFVNEVLNGIEEVAKMYDYDILLANTYS
                     DKEQELKSINLLRAKQVEGIVMISWIVEQEHINYIQNCGIPATYISKTARNYDIYTVS
                     TSNEEATFDMTEHLIKKGHEKIAFIMTSKDDTVLEMERLAGYEKALSNNNIELDKSLI
                     KYGGTDYESGYNSMKELLDDGIIPHAAFVTGDEAAIGAINAICDAGYKVPEDISVAGF
                     NDVKIARMYRPKLTTVYQPLYDMGAVAIRMVIKLINKELIENKKIELPYRIVDRESVT
                     ERKK"
     gene            complement(87738..87938)
                     /locus_tag="PC494_000369"
     CDS             complement(87738..87938)
                     /locus_tag="PC494_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3910899.1"
                     /translation="MLDRFFGEEGCFGGGGWWIIVLFFLFLAFEDCWRDIDIMSWIPF
                     LILLLITCSCGGFFDGEVGCGC"
     gene            complement(87972..88151)
                     /locus_tag="PC494_000370"
     CDS             complement(87972..88151)
                     /locus_tag="PC494_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3910900.1"
                     /translation="MLDRFFGEEGCFGGGGWWIIVLFFLFLAFGDSWAEFDIMAWIPF
                     LIVLLILCCCGGCLE"
     gene            complement(88333..88539)
                     /locus_tag="PC494_000371"
     CDS             complement(88333..88539)
                     /locus_tag="PC494_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3910901.1"
                     /translation="MTKLEDNMERFFGGCEGFFGNKMLIIIVIVFLLLCTDILEDLLC
                     DDNIWIWVILIVLLLFNFDDGCCC"
     gene            complement(88587..89012)
                     /locus_tag="PC494_000372"
     CDS             complement(88587..89012)
                     /locus_tag="PC494_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3910902.1"
                     /translation="MKYVGLLLTSVGMFLLIAVNFYYNSITLDMQRIEDYVMETNLIL
                     EDVAEKESYVSNEKEDYISRLMHVKKGIENSKTSFLIERYKEYKIKSIESLIYTISEE
                     KKDYLDEVDRYNKLGEKEINKLINKNFLEVTYLSITTYI"
     gene            89184..89411
                     /gene="acpP"
                     /locus_tag="PC494_000373"
     CDS             89184..89411
                     /gene="acpP"
                     /locus_tag="PC494_000373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HDF3910903.1"
                     /translation="MFEKIKEIIAEQLGVDNLDEITMEASLMDDLEADSLDAVEIIMA
                     LEDEFGIEIPDEEAENFKCIGDICKYIEENK"
     gene            complement(89555..90559)
                     /locus_tag="PC494_000374"
     CDS             complement(89555..90559)
                     /locus_tag="PC494_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HDF3910904.1"
                     /translation="MIIHKFIIHVLDKNSDVPILNDFEGKVNQEVDGFFQKAIKRIAK
                     DEDLRKGVFKDYNDNLIKNCCEQIIYDESTFLKNSKEIASYLFDVMKINAALESCDLA
                     ICLYTIKDEKSVAILKLDYKKLYTHSIEFVDDKFNIQMVSNEIGIPETLRQKQGALIS
                     LSGINDEFHLRLLDKDAEKEGSESKFVTEFLNAKKIDDDKYKTKVFKNTAENWITNAL
                     SNDIKQAEDVRSILNYTLKEKHEVDINDFVDNSIKDDELKDSFKEHMEEKGLDESFSI
                     DKKWVEKKLKKRSIKTDNGFDIKGNLTDFEDPMKYTVKQNQDGTIDIIIKNVTFYEEK
                     "
     gene            complement(90573..91475)
                     /locus_tag="PC494_000375"
     CDS             complement(90573..91475)
                     /locus_tag="PC494_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HDF3910905.1"
                     /translation="MFKKENQRYNLISYTNEEEMTLKEVLLDKLNFSVRSLSKMKREK
                     SVLVNGVYKKPSLKVYSGDLIEVKIDEEKANFEPQDLNLQIIYDDFDIIMVNKPPFMV
                     VHPTKSHYDKTIANGISYYIDNQKENVKIRFVNRLDMNTSGLVIVAKNAYAHHTLSTA
                     MSENKVEKKYITVVDGIIKENEGTIDEPIYRPTEDSIKRIIDERGQSSVTHYKVIERL
                     ENATVLEVSLETGRTHQIRVHMAHIGHGIIGDELYGYVDEELINRQALHAYKLEFEQP
                     RTKEKLKFKADIPEDMKELISKLR"
     gene            complement(91670..92845)
                     /locus_tag="PC494_000376"
     CDS             complement(91670..92845)
                     /locus_tag="PC494_000376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000786547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA C-acetyltransferase"
                     /protein_id="HDF3910906.1"
                     /translation="MREVVIASAARTAVGSFGGAFKSVSAVELGVTAAKEAIKRANIT
                     PDMIDESLLGGVLTAGLGQNIARQIALGAGIPVEKPAMTINIVCGSGLRSVSMASQLI
                     ALGDADIMLVGGAENMSMSPYLVPSARYGARMGDAAFVDSMIKDGLSDIFNNYHMGIT
                     AENIAEQWNITREEQDELALASQNKAEKAQAEGKFDEEIVPVVIKGRKGDTVVDKDEY
                     IKPGTTMEKLAKLRPAFKKDGTVTAGNASGINDGAAMLVVMAKEKAEELGIEPLATIV
                     SYGTAGVDPKIMGYGPVPATKKALEAANMTIEDIDLVEANEAFAAQSVAVIRDLNIDM
                     NKVNVNGGAIAIGHPIGCSGARILTTLLYEMKRRDAKTGLATLCIGGGMGTTLIVKR"
     gene            complement(92932..93777)
                     /locus_tag="PC494_000377"
     CDS             complement(92932..93777)
                     /locus_tag="PC494_000377"
                     /EC_number="1.1.1.157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxybutyryl-CoA dehydrogenase"
                     /protein_id="HDF3910907.1"
                     /translation="MKLAVIGSGTMGSGIVQTFASCGHDVCLKSRTQGAIDKCLALLD
                     KNLTKLVTKGKMDEATKAEILSHVSSTTNYEDLKDMDLIIEASVEDMNIKKDVFKLLD
                     ELCKEDTILATNTSSLSITEIASSTKRPDKVIGMHFFNPVPMMKLVEVISGQLTSKVT
                     FDTVFELSKSINKVPVDVSESPGFVVNRILIPMINEAVGIYADGVASKEEIDEAMKLG
                     ANHPMGPLALGDLIGLDVVLAIMNVLYTEFGDTKYRPHPLLAKMVRANQLGRKTKIGF
                     YDYNK"
     gene            complement(93875..94672)
                     /locus_tag="PC494_000378"
     CDS             complement(93875..94672)
                     /locus_tag="PC494_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase/isomerase family protein"
                     /protein_id="HDF3910908.1"
                     /translation="MSTSDVKVYENVAVEVDGNICTVKMNRPKALNAINSKTLEELYE
                     VFVDINNDETIDVVILTGEGKAFVAGADIAYMKDLDAVAAKDFSILGAKAFGEIENSK
                     KVVIAAVNGFALGGGCELAMACDIRIASAKAKFGQPEVTLGITPGYGGTQRLTRLVGM
                     AKAKELIFTGQVIKADEAEKIGLVNRVVEPDILIEEVEKLAKIIAKNAQLAVRYSKEA
                     IQLGAQTDINTGIDIESNLFGLCFSTKDQKEGMSAFVEKREANFIKG"
     gene            complement(94691..95701)
                     /locus_tag="PC494_000379"
     CDS             complement(94691..95701)
                     /locus_tag="PC494_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit
                     alpha/FixB family protein"
                     /protein_id="HDF3910909.1"
                     /translation="MGNVLVVIEQRENVIQTVSLELLGKATEIAKDYDTKVSALLLGS
                     KVEGLIDTLAHYGADEVIVVDDEALAVYTTEPYTKAAYEAIKAADPIVVLFGATSIGR
                     DLAPRVSARIHTGLTADCTGLAVAEDTKLLLMTRPAFGGNIMATIVCKDFRPQMSTVR
                     PGVMKKNEPDETKEAVINRFKVEFNDADKLVQVVQVIKEAKKQVKIEDAKILVSAGRG
                     MGGKENLDILYELAEIIGGEVSGSRATIDAGWLDKARQVGQTGKTVRPDLYIACGISG
                     AIQHIAGMEDAEFIVAINKNPEAPIFKYADVGIVGDVHKVLPELISQLSVAKEKGEVL
                     AN"
     gene            complement(95720..96502)
                     /locus_tag="PC494_000380"
     CDS             complement(95720..96502)
                     /locus_tag="PC494_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009524639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit beta/FixA
                     family protein"
                     /protein_id="HDF3910910.1"
                     /translation="MNIVVCIKQVPDTTEVKLDPNTGTLIRDGVPSIINPDDKAGLEE
                     AIKLKEEMGAHVTVITMGPPQADMALKEALAMGADRGILLTDRAFAGADTWATSSALA
                     GALKNIDFDIIIAGRQAIDGDTAQVGPQIAEHLNLPSITYAEEIKTEGEYVLVKRQFE
                     DCCHDLKVKMPCLITTLKDMNTPRYMKVGRIYDAFENDVVETWTVKDIEVDPSNLGLK
                     GSPTSVFKSFTKSVKPAGTIYNEDAKTSAGIIIDKLKEKYII"
     gene            complement(96561..97697)
                     /locus_tag="PC494_000381"
     CDS             complement(96561..97697)
                     /locus_tag="PC494_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA dehydrogenase"
                     /protein_id="HDF3910911.1"
                     /translation="MDLNSKKYQMLKELYVSFAENEVKPLATELDEEERFPYETVEKM
                     AKAGMMGIPYPKEYGGEGGDTVGYIMAVEELSRVCGTTGVILSAHTSLGSWPIYQYGN
                     EEQKQKFLRPLASGEKLGAFGLTEPNAGTDASGQQTTAVLDGDEYILNGSKIFITNAI
                     AGDIYVVMAMTDKSKGNKGISAFIVEKGTPGFSFGVKEKKMGIRGSATSELIFEDCRI
                     PKENLLGKEGQGFKIAMSTLDGGRIGIAAQALGLAQGALDETVKYVKERVQFGRPLSK
                     FQNTQFQLADMEVKVQAARHLVYQAAINKDLGKPYGVEAAMAKLFAAETAMEVTTKAV
                     QLHGGYGYTRDYPVERMMRDAKITEIYEGTSEVQRMVISGKLLK"
     gene            complement(98406..98873)
                     /locus_tag="PC494_000382"
     CDS             complement(98406..98873)
                     /locus_tag="PC494_000382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaK/EbsC family protein"
                     /protein_id="HDF3910912.1"
                     /translation="MSISNVREYFKQFGKEDSILEFEQSSATVELAAEAAGVIPARIA
                     KTLSFKIGDDAILIVTAGDAKIDNKKYKAEFNCKAKMLTPEEVLEFTGHAIGGVCPFG
                     LKNSIKVYLDDSMKRFDTVFPACGSSNSAIELTCEEMEKFSKCEKWVDVCKNW"
     gene            complement(98952..99494)
                     /locus_tag="PC494_000383"
     CDS             complement(98952..99494)
                     /locus_tag="PC494_000383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3910913.1"
                     /translation="MKKFIKVSFFILGIFTLFIAINKLVYRDMVSVKDYEINHLEEIV
                     FDFDSRRSRDVGTIVRFKISNNSKYSYKLNSAKMKFENCVENKKGMNKCSAYVNVDLF
                     NEKNSITERTLKYGIKPNNQGYVDFVIPKGLNFDYRYFNESGMSVEYKGEYIVNIPMA
                     KGLYLVVGKNNDTWNANIME"
     gene            complement(99546..100232)
                     /locus_tag="PC494_000384"
     CDS             complement(99546..100232)
                     /locus_tag="PC494_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 transporter permease"
                     /protein_id="HDF3910914.1"
                     /translation="MFNLIRKDLIIGISSDGIRNLKYILLFFVFYFFLNSISYYTVSI
                     VVSYLIFINTFECDYENDSRIFIRSMPVSIEDIVYSKYLLGVGLIISVTIIVSLLSKL
                     TSLVFFRNMVLNDVFFSVNIFLAILTILLPLIFKFGYGKMKVCGFIVSILIYFVYGSL
                     LKMISMIVYQVKHFNYSKVGGVYLSNYVTDIANTKYINLYSMTFLTIIIFIISMYFSI
                     KISKKNKFNY"
     gene            complement(100232..101092)
                     /locus_tag="PC494_000385"
     CDS             complement(100232..101092)
                     /locus_tag="PC494_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF3910915.1"
                     /translation="MFSIRNITKKLGKFKLNNINLELKEGDIVGIIGPNGSGKTTLIK
                     IIMGIIDADEGEIELCNETIENSPISFKNNIGFVYDSLQFYPHLKVKEFRKIVSLFYK
                     NFDRERFDEYLNKFDIEENMHIENLSKGQSEKLMLSSALSHNAKLLILDEPTAGIDPI
                     VRTEIMQYLQDFVKNGSSSVIISTHNTDNLIKIADYLVFINRGNQIFTVKKELIEQEY
                     KIIRANKAELEAIKESIVGVKEYKYYNEALVKVGDSLKVKSLLIEIDKHKVKNPTIEE
                     LMYYYVNEVR"
     gene            101227..102027
                     /locus_tag="PC494_000386"
     CDS             101227..102027
                     /locus_tag="PC494_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(+)/NADH kinase"
                     /protein_id="HDF3910916.1"
                     /translation="MKRIITINTNQLNKSLETKELLTRKLINAGFEVYSDIYPDTELI
                     ISIGGDGSFLRTVRDFDFPEIPIMGINTGHLGFFPDILPDKIDSFIEAYTKKDYIIQE
                     MSLLNAEVYTTTSGSNMLAVNEVVIRGDKSRTIHLNLSLDNKHIQNFSGDGMIISTST
                     GSTAYNYSAGGSIVDINLELMQITPLHPINTNAYRCFTSSIICSNESVIKIAPEYRFE
                     DSVLIVVDGVEHRFRQIENIKVSISDAKIKLLRMSNYEFWHRVSEKFL"
     gene            102052..102621
                     /gene="yfcE"
                     /locus_tag="PC494_000387"
     CDS             102052..102621
                     /gene="yfcE"
                     /locus_tag="PC494_000387"
                     /EC_number="3.1.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphodiesterase"
                     /protein_id="HDF3910917.1"
                     /translation="MKIGIMSDTHGSLLYFEKALNVLSDCDVLLHGGDVLYHGPRNDI
                     PEGYNPKKFIETLNKLENIVIVKGNCDADVDQMVIEHPIQSPYVMSQFGEIRIILNHG
                     YIESEEEIIDKAKKMGGDILVLGHTHVKKLYMDDNLIVINPGSTSIPKDGSHSVAIID
                     IIKTDDEDELELDINLIDINTGNIININD"
     gene            complement(102957..104009)
                     /locus_tag="PC494_000388"
     CDS             complement(102957..104009)
                     /locus_tag="PC494_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp18"
                     /protein_id="HDF3910918.1"
                     /translation="MKIKSKKIIAFALSLGIMLPSCVYADTISKNQNAQVDMNNYLQG
                     RKSPKEEKLIGEDRFDTAIKISQSGWNNGSERVFLVNSNSLPDALASTPLASKLDAPI
                     LLTNKNSIPYNVTEEIKRLNPAEVILIGSEGAISSSVKESLEDMEVLVSRIGGADREE
                     TSLLLTRQLDDTGDLGVSKVAVVNGYNGLADATSISSPAASDNTAIIYTGKDSIRSEA
                     KNFITQNSTKTYIVGGEYSISKKLEGQLVNSERLAGTDRKDTNAKVLEKFYGKSSKVN
                     NMYFAKDGSGREADLVDGLAAGVLASKTKSPVVLASGSLSSAQKSFIKKVKADKFVQV
                     GGGKNSKPYAEALALQ"
     gene            complement(104235..105461)
                     /gene="pepT"
                     /locus_tag="PC494_000389"
     CDS             complement(104235..105461)
                     /gene="pepT"
                     /locus_tag="PC494_000389"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HDF3910919.1"
                     /translation="MKQKVVERFLKYVSFDTTSNSQCENCPSSEGQRVLAKYIVEELK
                     TMGVDDVSLDENSYIMATLKGNTDGVDTIGFISHLDTIEDVSGKDIKPRIIENYDGKD
                     IVLNEALNVITYVKDSPELEEFKGDDLIVTDGTTLLGSDDKAGIAEIVTAIEYLINHP
                     EIKHGDIKIGFTPDEEIGRGADLFDVEKFGAKYAYTLDGGIVGELECENFNAANATIT
                     IHGRNVHPGSAKNKMVNAIHIAAEISEMFPADERPETTEGYEGFWHLNSIGGNVENVS
                     MAYIIRDHCKEKFENRKSIMIENIEKINKKYDNRVELDLKDSYYNMKEKIEPVMFIVD
                     IAKEAMEELGIKPRLVPVRGGTDGARLSFNGLPCPNIFTGGLNFHGKNECIPVSSMEK
                     ATKLIVRIAEKYAERV"
     gene            complement(105552..106604)
                     /gene="ytvI"
                     /locus_tag="PC494_000390"
     CDS             complement(105552..106604)
                     /gene="ytvI"
                     /locus_tag="PC494_000390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation integral membrane protein YtvI"
                     /protein_id="HDF3910920.1"
                     /translation="MSILENNFLYKLKNNTIFFCIYTLLFIFIYKAFPYIAPFFLGAI
                     IALMINPISQKLENKFRINKGISTLVLSFLAVAIVSTVTTIIVINSMKELMGFLNNIS
                     ANPEDISNTIMYFLNKINDFMKSFQEIANFDVEQLVNKFSGEVMQITKNLLTSILGLA
                     TSIPYIIIFIITLFIATYFIAKDLDKIENSFYNMFTVDVRKKVKNVKKEAGLSLVGYI
                     RAYTILMAITFFAIWGSFALFGLKYGLIVGFVGALMDLIPFLGIITIYLPVIVYYFLI
                     KNYFIAISMTVIFFVLSLIREILEPKLVSVNVGLNPLATLAAIFIGIQVKGIIGVIFC
                     LGLVCMHDILKKVDIF"
BASE COUNT        33996 a        19360 c        11419 g        41927 t
ORIGIN      
        1 taataaagtt attttaataa catttaacca gttttttatg taggtaacat ttctacattt
       61 ttataaattt ttttacgttt tttaatttta taattaaaaa tttaaatttt atacatatta
      121 taataaattg tgatatatat aaaataatta aagataaaag gagtatttta tgaacatact
      181 tggattaata gttgaatata acccatttca taatggacac atatatcatt tatctaaatc
      241 tatagaaaaa acaaatgcaa cacatactgt agcaataatg agtggaaatt ttctacaaag
      301 aggcgaacca gctttatttg ataaatacac tagagcaaaa attgctgtcg aaaatggtgt
      361 agacttagtt atagaattac caactttatt tgcttgtcaa agtgctgaaa ttttttctca
      421 tggtgctata acaattttaa attcactaaa ctgcataaat tctatatgtt ttggtagtga
      481 agaaggaaat acagaaattc tttataatat agctgaaatt ttagcaaatg aaccaaatga
      541 atttaagtta cttttaaaaa aatatttaga tgatggtctg ttatttccaa cagctagagc
      601 taatgcgctt tttgattata tacatcaaga caaaaaaaat aactttatac aaaattattc
      661 aaaggaacaa ttatcaaaaa cattaaattc atcaaacaac atactgggta tagaatacat
      721 aaaaaacctc atccatttaa acagtagtat aaaaccattt actatctcca gggtccaatc
      781 agaatataat tccgaagaaa ttgagagtga tatttgttct gctactgcta taagaacttc
      841 acttaaagaa aatacagacc tttttcattt aaaaaatgtt attccagaaa aaacttataa
      901 catcctaaat gaaaaaatag ataatggttt tttacctatg tttgatgact tcttctttga
      961 tattttaaaa acaattatac ttagagatat ggacacttta aaagagtatt ttgaagtaaa
     1021 tgaaggcata gaaaacagaa tctataaaga tatctttaca tctgaatttc tacatgaact
     1081 acaattagca attaaatcca agcgatacac tttaaccaaa atcaaacgaa ctctaaacaa
     1141 tatattgtta ggtattaaaa aaagcgacat gcaacttata aaaaacatag atactatacc
     1201 ttatataaga atacttgctt ttaatgataa aggtagagaa attctaaaag agataaaaaa
     1261 taaatctgaa ataaaaataa taaacaagtt ttcaaatata tcattttcat tagatgatac
     1321 gatttttaaa acactcataa gttatgatat aaaagctaca aatatatata attcaatata
     1381 ttataaaaac aataaagatt tagtaaaagg ccctatggat ttttatactc atccaatata
     1441 tgtaaagtag ttttttaaaa taactatatt tataaaaatc attttattaa ctctttatta
     1501 tataagatac aatagtctta ctttatttat gtacacatgc ttttaggatg acaacatcaa
     1561 cttaaatatt atgttacttt ctaaatttaa gtaaatattg ccatcctaaa aattttacaa
     1621 tttagcttca gatttaaaag taaagtttaa aatattatat ttaaatctaa tttaatattt
     1681 tttgttttat aaatattatt aaattaatat ttctaatata ttttccctgg atttaaaata
     1741 tttttagggt caaaagctaa ctttatattt ttaattaaca tcatataagc atctgaattt
     1801 gattcatgta agtactcttt tttagcatat cctatgccat gttcaccaga aacttgacca
     1861 ctaagttctc tagatttttt atacatatag tcaaaagttt cttttaatct tattttccat
     1921 gtattatcat ccataccatc ttttaaaata tatatgtgta gatttccatc tcctgcatga
     1981 ccaaaacttt ttattcttat ttttaatttg tcttgaagct cgtgagtgta tcttataaac
     2041 tctgctatct tatctcttgg aacaacgaca tcacattcat ccatttgtgt cgtagatgcc
     2101 tttatagctt ctaaaaatgc acctctggct gaccatatag aatcgtttct ttcttgtgta
     2161 tctgatataa atacatctaa tgcaccattt tctaaacata aattagctac tttttcatat
     2221 tctttttcta tatcttcagt gctatttcca tcaaatgtaa gcaaaagata agcatctgat
     2281 gtattatctg gaaacttttt acctaaaaat tcttctgctg ccaatattac atctctttcc
     2341 ataaattcta tagccgttgg tattgatttt gattttatta ttttaggaac agtttctatt
     2401 gccattgata aatctggaaa tggtataagc aaacttatac ttttctttgg taaaggaagc
     2461 aattttaata tagctttagt aactattcct aaagtacctt ctgaacctac taataaatcc
     2521 tttatactat atccagaact atttttaacc acctttccac ctacatttat aatttctcca
     2581 tttggtagta caacttcaag tcctcttaca taatcccttg taacgccata ttttactgct
     2641 ctcataccac ctgcattagt gtttatatta cctgcaattg tagcactttt ttcacctggg
     2701 tcaggtgggt aaaataaatc tctatcttga acatattgac ctattgtcat caataaaaca
     2761 cctggttcta ctgtcaatgt taaattttca taatcaactt caagtatttt attcatttta
     2821 catagattaa tcattattcc accatttatg gcaacagcag cacctacaag accagtacct
     2881 tgacctcttg gtgtgactgg tatattattt ttatatgcgt atttcattat tttagatact
     2941 tgttcagttt caagtacatt tactaaaact tcagggtact tctcaatccc tccaagttca
     3001 tcatgtgaaa aatcttcatt tatatcactt ccaactaata cattttcttc tccacaagta
     3061 tctattaaaa aatctatatc ttttttatcg attaatttat acatttctat ccccctattt
     3121 agctgctgat gccatatatt tttgattatt atctttgtta ttttctattt tttcaatcaa
     3181 tttaggaata atatcataaa tatcacctat taaagctaaa tgtgctacat caagtatagg
     3241 cgctttatca tctttattta ttgctactat atagtcagca ccctgcatcc ctgcaacaaa
     3301 ttgaactgct ccagatacac cacaagttat tatcaattta ggttttacag ttctaccact
     3361 aagacctatt tgttttttag catctatcca acctgcttct attacaggtc ttgttcctgc
     3421 cacttgagcg tttagcttat cagctaattt atatatcatc tccatatctt cttgtttttt
     3481 tattgctcta cttgccacaa ctatcacttc agcttcttcc agaccaactt ctttattttt
     3541 ttcttttaca ctcagtacct taattttaga ttttagttct tttttttcta ctttacataa
     3601 agttatcttt cctgtagtat tctctatttt ttctggtgct gaaaatattt tatatcttac
     3661 agtggcaaat tgtggtctat tattaggtgt gtttatatga gccattatat ttccaccaaa
     3721 tgctggtctt atttggtcta aatcagtatt tgattgaata tcaagtattg tacaatctgc
     3781 tgtaagacct gttctaaatc tagcggcaag tcttggagct aatgacctac ctaatgtagt
     3841 tccaccaact aatactatcg ttggttttat tttatctata aagttttcta ttgcttttga
     3901 atatggttct atcctaaaat ctttaaattc atcttcatca tatacaaata cttcatccac
     3961 cccataagaa atcaaattac tgcacttatc ttttatgtct tttcctacaa atacacaata
     4021 cacaggttgt tttatttttg atgccatctc acgagcttta cctataagct cgtacgttac
     4081 aggatgtata tttccattat gatgttcaac atatactgca attcccctcc attcatcttt
     4141 attaatttgt actttactac tctctataaa ttcaaatgcg ccttttggtc cacttttgac
     4201 acacaacttg cacatcttac agccagcact tatttctact atacctgact tttcttctat
     4261 agccccaaaa ggacatattt ctaaaattct ctttaagtca gttattttat cttgatttac
     4321 aactatcttt gacatttatt actccccctt acaccaactt taattcctct aatttattta
     4381 caagtgcaaa acttagttca tctgcatttc ctcttacaat atttttatct gtatttggct
     4441 ttggaggaaa tattcttaca acttgagtag gagaaccatt aagtccatag ttattttcat
     4501 ccttatcttc aaagtcatct aagctatata caggtatttc tctatcttta gtattaagtt
     4561 ttaatttaaa tgaaggtagt cttggttgaa aaatgtcttt ttctacagtt attaaacatg
     4621 gatattcaat ctcacatact tgtaaatcat ttggcatatc tatttcaaca actatacttt
     4681 catctttaac ttcaattaat tttgtaacgt tagtaacatg aggtatatct aaaaattcag
     4741 ctacttcagg tcccacctgt gctgtatcac catcagtagt ttgttttcca caaattatta
     4801 ggtctacctt tcccatcttc ttaatacctt gtgatatggt ataggaagta gccaatacat
     4861 ctgctcctcc aaatctccta tcacttatta atgctccttc atcagctccc atcataaaac
     4921 tttcttcaat taccttcttt gcctgaggag gacccatgct aagtactttt agattcgctt
     4981 tcttatcttc ctttattcta agagctgttt ctaaagcata taggtcatag ggattcattt
     5041 ttgaatctac tccatctctt tttagtactc ctgtagtttc atcaacttct actgaagtcg
     5101 ttccaggaac ttgtttaata catgtcaaaa tttccataaa gtacactcct tttttattta
     5161 actataactg atactccatc aggtataact actactttgc tctccttacc aactatacta
     5221 ttcgccattt ctaaagcttc tttaaagtta aatgcatgtt tcatatgcat tttttttatc
     5281 atttcaggat tacacttatc tgttaccatt atcacagtat atttagataa tattctcgct
     5341 agtatctgaa attcccattg gtctggaatc gtatctactc tatcgacact tctaatttta
     5401 tctaaaagtt gttttggaga atctgcattt gctacatttt cataaaaaga ttgacctcca
     5461 tgaccatcat tacatgctga aatcattatt attactccac cgtctttaca agtagcttca
     5521 gctgctgtca ttcctttaac agattgataa atattttggt ctagtggata tccaccattt
     5581 gtagttacaa caatatcaga ttttatagaa tttacttttg ataactctgt tacaaatcta
     5641 catcctttag tatgtgcttt ttcgacatca ccagcaaagg aagcaattat ttttttatct
     5701 ttatctatta caacattcaa tatgaatgct aattttgcaa ctttagctgc atataccata
     5761 tcctcatgaa taggattatt attcaatttt ccagttcttg aattatcact atctataaag
     5821 tcactacagt gattgtacat tatagtcttt gcagatgcga ttcctggaag tacgcttttt
     5881 ctgccacctg aaaaacctgc aaagaaatga ggttctataa aaccttctgc tatcaaaagt
     5941 tctgcctcat atgctagttt gtttatatat aaatctccac ctgaaggcaa tatccctact
     6001 ttacacatag atttatcatc agtagatata tgcataacta tatcttcatt atctactatt
     6061 tcttctccca ttttataaat tagctcttcc cttgtacttg gcctatgaaa tccagttgcc
     6121 actataatct tcacatcaat ttctggatta acattcctaa tccttcttaa tataattggc
     6181 atagttattc tacttggtac aggtcttgta tggtcacttg taattatgac tacattcttt
     6241 ttccccttaa ccagttcttc cagagaatta gagcctatag gattattcat agattcttca
     6301 actatctctt cttgagtctt atgttctata taattatccg attttgactc caaaacaccg
     6361 agaaaacgtt catcaggtat ttctaaaatc attccttgtt ttgaatacgg tacttttaac
     6421 tttaccattt ttaatctccc attataataa actataaaat tggtatgtgg tcataccagt
     6481 tttacattta tatgatagta ccattatcta ccatttgcaa gaataattta ttttataaca
     6541 aacttttaat tttcattttt tctataattt ttacttataa aatccatatg ttcctttgct
     6601 ttctcacatg caagttctac atcattttct acaactgcat tgtatatagc ttcatgctgt
     6661 ttaagcaata tattttcatt aaaaggttct gcgattattt tttctcttgc atcttctata
     6721 aatccatcaa ataattttga tgctgtcata aaaagacttt gaattaaata atttttactt
     6781 aatgttgcta gtttactgtg aaatttttgg tctaataaca ccagtactcg attattatct
     6841 tttttattag tttctaccct catttcatct attatatgtt tcaattctat aacttcagaa
     6901 gaagttattc tctttgaagc aagttttgca atctcaattt ctaggattat tctaagctct
     6961 aatatatctt caagtgtacc attattaagt ttaaaaatca tagataaagg ttctattaaa
     7021 gttttttcta tatttgtaca tataaaattt ccttcaccct gtctgctttc tatcactccc
     7081 atagtctcta ataccctaat agcttccctt atggaagttc tactcacatt catttgttca
     7141 gacagttctc tttctgatag taatttatcc ccctttttta actctccatt tagtatttta
     7201 tattgtattt gctcaattac ttgttcataa acttttttac tagctatact attaaacatt
     7261 ttttcctcca atatgataat cgttgttgta atatatatct attatatatc ttaagccatt
     7321 acattcatat atttttatta cttttaatat aatatcttat aactcaaatt tacaggtgat
     7381 attatgaaaa aaaataaaat tattgctttt tttgctccat ctatcatagt tggagttcta
     7441 gttttaggga ttatcctata cccaaatgaa gctataagat ctgcaagaga aggcttttct
     7501 atatggtcta atgttttagt tccatcacta ctaccattta taattggagc aaacttaatt
     7561 gttgatttaa aaatagtgga tattataggg tttatcatca atcccataac tagatttgta
     7621 tttaatgttt caggaaagag cgctttagct tttgctatat ctacagtatc tggttatcca
     7681 gtaggagtaa gtttagcttc tgaatttagg agtaatggac aaatttctaa gtatgaagca
     7741 caaagacttg tgtctttttg ttctacatca ggacctttat tcataatagg ttcggttggt
     7801 acaggtatgt tccaaaattc aaacttaggt tatttaatga ttctctgcca ttatctagga
     7861 actatattgg ttggtctttt ctttagaaat tatggtaatg aaaatcttcc aaagacaaaa
     7921 ttggatttaa aaacaaatat aaaaaatgta atcaacatta gaaattcaag tgggaatggt
     7981 ttttttgttt tatttggaaa tgctgtattt aatggagtaa acacattact tacagttggt
     8041 ggatttgtaa ttgttttttc agtcgtattt aaaatactat ctctttttaa tgtaatctca
     8101 ttaatagcat cagttatata tttgcctctt tcatttttag gtgttagtaa agaactctgt
     8161 caagcatttg taagtggtct atttgaaatt actataggat gcaataaagt atctagtata
     8221 acaagttctc cagaaatttt aagagcatct ttagctagtt ttttgatagg atttagtgga
     8281 ttatccatcc tagctcaatg ttgtacattt ctatcaaaaa cggacataga tttaaaatta
     8341 tacatactaa gtaaatttgc gcatggagtt ttagctgcta tctttatatt tatactttat
     8401 ccaattgcaa actctgctgt gttggtttct agctttgctg atacatacaa cgttatatat
     8461 aataatttaa tctggtttta ttatcttagc tattatgata caattcttca agttgtagta
     8521 ataatttatc taatctcagc cgtatttatt gcaaaaaaac atatgaaaac tttatctaca
     8581 aatgggaaac taatgcgata taaaaatact tttttcacta agaaattttc acgaaaaaaa
     8641 taaaactaaa aataaaacta ataaaactta actaaatact tccatttttt tattatattt
     8701 gtcataattt taataacctt tttaattagt ttaacagcat agttatttca tcacaattta
     8761 ataattttat tagaaatatt tttcaaaaaa ttctccttaa tcacatatat cacacttgta
     8821 taagtttact gggaaatttt tccattatat aatatttcat ttatattata taataaatac
     8881 cgacctaaac ttaccaaatc aaactaagag gagtggttga aaatggcaac aagacctata
     8941 gaaatagacg aatataaaaa gataatggaa ctattacata ctggctttac ttatagtgaa
     9001 aatggcgttg aaaaaagatt tagaaaaaat cctaaagttg cattggcact aatgttagaa
     9061 gctaatttag gtctaagaat atcagatatt ttaagattaa agataggtaa ttttaaaggt
     9121 aatatgttgg aaataaatga aaaaaagacg ggcaaattac agtatagacc agttaataaa
     9181 aatataattg agtccataaa tgaacatgca agaaagtata atcttaaatc aaatgactac
     9241 ttagtaaata taaagacaaa ggctattcaa aaacagttga ggataatttg taaacactta
     9301 aatctgtata atataagtac acatagcttt agaaagctct acgctactac tcaatttgaa
     9361 aagagtaaca ataatttaga gttggttaaa gaacttttaa atcacagctc tgtagccact
     9421 acacagcgat atataagggt aactcagcaa gctattaatg aagctagtga aaatttcttt
     9481 attggttaat tataacgtat acatttttct attatcttat taattcacca gatattaaaa
     9541 aagagtgtct caaaatgaac tttttagttc ataagacact ctttttttat aaaatcaaat
     9601 atatttttat tatttcaaca ctggaaaaaa ggcttatctc tctattttga gacaccctat
     9661 taaattttca taattcttgc ataaacatat taatctatct tcaataattt tttagctgat
     9721 tcactgtaat tatttctttt tacaatttcc aaaactctat caatctcatg ttctgacttt
     9781 gcacttacaa aaatcgccaa ttcttcatca tctataatat cataactatc tacatattta
     9841 tctaaacatt ctaaaattcc atctttatta ttatacccac caaatctaac tactgcacta
     9901 cactcatctt ctataagtcc acttaaatcc aatttccctt ttgaaaaaga ctttatattt
     9961 gaacttctat tatctattat atctataata tctgcataaa cagcacttcc tgttgcacct
    10021 cttccagctc ccttacctac aaaagaaagt tcacctactg aatcacctac taaaataact
    10081 acgttgaact cattatctat ctttgaaagc atattattat tgtccactaa tgctggtcta
    10141 acaaatccac ttacttctcc tgattcatac ttacttctag caaccaattt tatcttacaa
    10201 tttaattttt ttgcatattc tatatctttt tcatctattg aagttattcc ttctaataat
    10261 aaatctttcc aatatactat ttttccataa gataaagtag acaatataga taactttcta
    10321 gcactatcat atcctaaaac atctgcatct ggattaactt ctgcaaatcc caactcttgt
    10381 gcctgtttta aagcgacatc atatggtaaa ttttcatcat acatctttga taatataaaa
    10441 ttacaagtcc catttaaaat agcgtttatg ctctttatat tgttgccttc cagtgattct
    10501 atcaatggtt ttaaaactgg aataccacct gccacagatg cttcaaactt gatgctaaca
    10561 ttatttaagt tagctaattc tataaggtca ctaccttttt cagccagtaa atctttatta
    10621 gctgtcacta catgtatttt tttatttaac gctcttgtta cataatcaaa agctggattt
    10681 aatcctccaa ttacttcaac tagtatatca atatccttgt caaatatatc ttctatatca
    10741 gtagttatct tatcaaaata cttcttatac ttgtgttttt ctttattttt aactaaaatt
    10801 ccaacaactt ctatatctct ttttgaagta ttattttcta ttaaatcaat taatccactt
    10861 cctactgttc cataccctaa tattgctatc ttcactgtaa cataccccca tcattttgat
    10921 tatattaaat tatttatata tataaatata ccaataaaaa aagcttgagt ataaactcaa
    10981 gccatatgac gggtttatac tcatctttca gcataaatgc tgcaggattt agcaccaatg
    11041 tataattaaa tatactggtt gccgggcttc acagggccag tccctctgcc actcttgata
    11101 agattgctaa tttaaattta tgtttaatag tataatacaa tttcttccaa ttgtcactat
    11161 ttttttaact tatttcccta aaaggatata aactattatc taacagctct tttagttggt
    11221 ttaccctttt ttgtaacatt attattttta gtctttgctt tcgcctgttc atgtcctgga
    11281 aaaagtattt taggctcttc aatattcctc ttgtaaatag taaatttaaa accaatagcc
    11341 tgcacaaatt cagctcttaa agcttcacat actgcattag cagtttcttt agtatcaaga
    11401 cctgcatttt ctaatatagt aacttttact aattctctag ttcttaacat accatctaat
    11461 tgctctaaga aactctctgt aacaccttct ttaccaattt gtgtagtagg ctttaaagta
    11521 tttgccaaag atcttaaata cgccctttgt tttcctttta acatattctc acctctataa
    11581 ttctatactt aaattatcta taatctatat ttaaattaat tgtaaaactc aaattctaat
    11641 tcataaattt taaccacatc tccatcttct attcccattt ctctaagcct atcaaaaaca
    11701 ccttgacttt ccatagcttt ttggaaatat tgaagggatt ccatatcatc aaaatttaca
    11761 gaatacatta ttcttctaag tgctttacct gtaactacat acacaccatc ttcaatatct
    11821 atacttaact cttcttcagt accaatatca agttctggtc tatacatttc ttcttctgaa
    11881 actagctcca catcttctac ttcttttagc attttagaaa cataggctat tacttcatct
    11941 atgccttgac gagttgctgc tgacatttta aatactgtat atcctctgcc ttctaattca
    12001 ctcttaaact tctcaaactt actctcatct tctaatatat caaatttatt tgcaactaca
    12061 acttgtggtc tctttgaaag cttttcattg tacaatttaa gctcatcatt tatcttgtca
    12121 aaatcttcaa tagggtctct tccctctaat ccagatatat ctacaatatg tatcaatacc
    12181 tttgttctct caacatgtct taagaactca tgacctaatc ctatgccttc agaagcaccc
    12241 tctataattc caggtatatc tgcaagtaca aaactatctc caaacttagt ttgaacaaca
    12301 cctagatttg gtgtaagtgt tgtaaaatga tagtttgcaa ttttgggttt agctttagtt
    12361 acaactgata gaaatgttga tttacctaca tttggaaatc ctaaaagacc aacatctgct
    12421 atcattttaa gttcaagagt tatccatctt tcttctccat ctgtaccaga ttttgcaaaa
    12481 gctggagctt gtcttactgc atttgcaaag tgttggttac ctttaccacc tataccacct
    12541 tttgcaacta tagctgtatc tccttctttt tttaaatctg ctaatacaag acctgtagcc
    12601 tcatctctta ttactgtacc tgctggtact tttaatacta aattttctcc atttttacca
    12661 gctctttttc ctttgcttcc gtcgccacca ttttgagctt gatatttttt ctggtactta
    12721 aagtccatta gagttctaag ccccaaatca acttcaaata tgatgcttgc tccacgacca
    12781 ccatctccac cgtctggacc accagctgga acgtattttt ctcttctaaa tgctaccgaa
    12841 ccatttccac catttccagc cttaacaaat attcttgcct tatctataaa caaattcttc
    12901 acctacttaa ttaaaaactt ttaattagca ttaccaaaaa taccattata aattcatcag
    12961 tattataaga aaaaggagtg cctcaacact ccttttatgt atattactca gctattgcta
    13021 ctggatatat actaactttt tttctcttct tgtcttttct ttcgaactta acagtaccat
    13081 caactaatgc aaataaagta tcatcactac cttttccaac attagttcct ggatgtattt
    13141 tagttcctct ttgtctaact attatacttc cagcagttac taattgacca tcaaatctct
    13201 taacacctaa tcttttagat atagaatctc taccattttt agaagaacct accccttttt
    13261 tagatgctaa taattgtaaa ttcatgttta acatatggag tcacccccta cttttttaaa
    13321 atttttatat tttttgggta ttcccgttta atttctttaa ccgctaattg aaagtgattt
    13381 agtaataatt gtgcgtcttt tacatgtgta tctttgacta tacactctat atgaccttct
    13441 tctcctacta ctttttcaaa ttcaatcttt tttaatttgt ctaaagaatt tataactgca
    13501 atagcattag atgtaactgc agcacatact atatcatagc ctatttcagc aaaatcagca
    13561 tgtcccttta aacaaaaacc ttgcaacaag aaatcatcat tataataata tttaactttt
    13621 atcataactt aaccaataac taagcgttta ttttttctac aactatctta gtgtatgatt
    13681 gacgatgtcc ttgttttctt ctgtaatctt tttttgcttt atacttgaaa actataactt
    13741 tcttagcttt accttgttca acaactttag cttgaacaga tgctccttct actactggag
    13801 aacctaattt taattctcca tctttagagc aagctaatac ttcgtttaaa gtaacaacat
    13861 cacctgcgtt agcttctaat ttttcaacga ataatacatc accttcagaa actttatatt
    13921 gctttccacc agtctttact atagcgtaca ttaaatacac ctcctcggcc tcaaactcgc
    13981 caatacaagg tacttcattt gaagatttaa acctttactg tgcggcatta caattattaa
    14041 ttataaaata tttacatttt attgtcaact attttatcga aaataacatt ggttttattg
    14101 tgctttaatg tactatttgc gtttaaagaa atctttatat tatatttttc accaatttta
    14161 tcaattatat ccatataata ttcttttatt tgttcaaaaa taaaatcatt aaattctacc
    14221 attatgtttt tgtaaacagt atgttcactt attctcataa tttctttttc aatactatct
    14281 agtatataat gtacagattt tattgtttgt tcaccatcac aacatggaca agacattaaa
    14341 taatacttat caatggattc tttttctcta cgcctagcaa cttctactaa accaagtttt
    14401 gtcataccta atacttcagc ttttctttta tctttattaa attcttcttc taggatgtgt
    14461 aaaatctcct tttgatgctt ctttttatgc atatcaataa aatcgattat tattatccca
    14521 gctatgtctc taattctaag ctgtcttaca atttcttttg cagcttcaag attagtttta
    14581 taaacggttt catcaagttt accagttcca ataaacttac ccgtatttac atctataact
    14641 gtaagagctt ctgttttttc aattattaaa taacctccac tctttaacca tactttttta
    14701 tttaataatt tttctatttt agattctatt ctgtataaat caaatacatc tctattttcc
    14761 tcaagacaca gtttatcaac ataagtctta tctatacctc ttaaaataga cttaagttca
    14821 gagtacttat cataactatt ggtaattata gattcaatat catcattcac attatctttt
    14881 acatatttag ttgcaaaatc taaagactta tataataatt tcggacctat accaagttta
    14941 tattctttta aaatgttttc atactttaat ttcaactctt ctatatcttt ctttatttca
    15001 tcatgagtgc aaccttgagc ctcagtcctt attattaatc ctagattttc cttatttact
    15061 gccttagtaa ttttttttaa tctaaatcgt tctttttcat cagtaatttt atttgatatt
    15121 gtagttctat cattggaagg tatatagaca atataccttc cagaaatact aatctcagtg
    15181 tttaattttg cgcctttagt tcctatttct tctttattta tctgaaccaa aatatcctga
    15241 ccagatttta tagtacttcc cttttttaat tgtaaataag caagtttctt aaatccaata
    15301 tctacaaaac aagcttctat tcctggtata acttttttta cgattccacg atatatattg
    15361 gatacagtct tcttatttaa attgtcttca acaaaaagtt ctgttaatct ttcatcttca
    15421 agtactgctg ttttctggga ccctattagg gactcaataa ctatcttttt cacaacttca
    15481 cctctcgagc ttacatagga gtcactaatt ccccatcttc taatacatat aaatctcttc
    15541 tcaatatatc aacatctaat gggtcaatat caagttcaaa catctctaat atctttggta
    15601 taagtatatt agtatttaaa ttagtttttg agcctgtagc tatagtagca gtaagagtaa
    15661 tatgttcatc ttctaaattt aaaacatcaa aggttcttat cataggtctt atatctactt
    15721 caaccatctt acctttttta ttcttttttg ttatgattat ttctttatta ttcataaagt
    15781 caattacttt tctttttaca aactctttcg tcataggtct tttcaaatct atattaaaca
    15841 aatattctcc atagtctatc acagaagaaa gagaaggtgt ttgtctatca atttcttttg
    15901 ctttgataaa atctatccca tctggaagtt gaattgatac tttatttaaa aattcctcta
    15961 ctgataaatc atcttcttct atttcaatat ctacatactc accttgactt tctgtcccta
    16021 aagccaaagc attgccataa ctcattttag ggtgaggatt aaatccttga gaatgtgata
    16081 agtttatttc agctcttcta aacgctcttt gtaacaatct ctgaaggtca agatgtgata
    16141 tatatatcat gtcgccttcc tttttaaatt ttactcttat tatcttactc atattagcaa
    16201 agcccccttc ctatatcatg tatatttatt ccacaaccat tgcagttatg tctacaatca
    16261 gaagtgattt tttctttttt agcattttcg tcttctctaa ttaagaattt tttactaata
    16321 cctacatcta tatggtccca aggaaatacc tcttcatagt ttctatttct atgtgcataa
    16381 aaatctatag aaagattatt cttttccata gcttctttcc atatatctaa attaaaatgt
    16441 tctgcccatc catcaaattt agcacctagt ctaaatgcat catatataac ttttcctatt
    16501 cttctatcgc ctctagctac tactgcttcc atcaaactag tctttgaatc atgataattg
    16561 tattttatat tgttatttct taatttattt actaaatgtc tctgcttatt aataacttct
    16621 tctgtagtat cttgaccatg ccattggaaa ggtgtaaatg gctttggtac aaatgtagaa
    16681 gtactcactg taacactaaa acttctcttt agctttcctc catttacttt tctataaata
    16741 tcaataactt tataagctaa tttagctata ccatctaaat cttcataagt ctcagttggt
    16801 aaaccaatca taaaatacaa cttaacacta ttccacccca tctcaaaagc tctttctgtt
    16861 gcattttcca aatcttcttc tgtaacacct ttatttataa catctctaag tctttgagtt
    16921 cctgcttctg gagcaaaagt aagtccagat tttcttactt gttgtatttt atcagcaatt
    16981 tccattgaaa aattatctaa tctaagggat ggaagcgaaa tcccaatatt attagatgca
    17041 tattcatcta ccaaataatc agtcaactct gataacttac tataatcact cgtactaagt
    17101 gatgataatg atatttcatc atatccagta ttcttaacta atttatctaa tatttcttta
    17161 agtcttttaa cactcttttc tcttattggc ctgtatatca tacctgcttg acagaatcta
    17221 catcctctag tacatcctct aaataattct agtactattc tatcatgaac agtatctata
    17281 taaggtacta ttagtttttc tggataatct acagtctcaa catcttttat tatcctttta
    17341 gtaggatttt tagtaatccc ttctctatta ggagttacac tttgaactgt accatcttca
    17401 ttgtacttga catcataaaa acttggtatg tatactcctt ctatgctaga tattttatat
    17461 aaaaaatctt ctctagtcgt tttatttttc ttccattctt tatactcatt tactacttct
    17521 aaattaacct cttcaccttc acctaatatt actacatcta caaaatctgc taatggttcg
    17581 gaattataag cacaaggacc accaaccatt ataaatgggt cttccaaagt tctttcttct
    17641 tttaatattg gtatattggc taaatctaat atatttaaga tattagtgta tgaaagttca
    17701 tattgaagtg taaaagtgac aaaatcaaag tttgttatag gctctcttga ctctaatgca
    17761 aataatggta tacttttttc tctcattata ttttccatat caactgcagg agaatacact
    17821 ctctcacaaa atacatcttc atccttattt attacatcat ataatatatg actccctaag
    17881 tgactcatac caacttcata taaatctgga aagcaatgtg catatcttat caattcacta
    17941 ttactagtat ctttatgaat tgaatttatt tcatttccaa gatatctagc aggcttttct
    18001 acttttttta agattttttt caagtctact ttattcattt attaaaattc ctccaaacaa
    18061 gctctttatt tttattctta tttataagta atattataca cgataaaata ttttctatca
    18121 aaaatataac taaaatattg aatttaaaat acatattatt cacaaaatag aatagctaaa
    18181 aatatttaag aatattttct attaaatttt tattgaaata caattttttt acaaagtatg
    18241 atatattata aacataaaac tattgtttta catgacttat catgacatct tttgtttcat
    18301 tcacctcaaa atggggtatg ttacttatat aatgataaat tttaggaggg ttaaaaatga
    18361 gtaaagtttt tgaagtaaaa aaagatatct actttactgg cgtagtagat gaaggtttaa
    18421 aagtattcga cataataatg gaaactgagt ttgggacaac ttacaactct tatttaatca
    18481 aggacgaaaa aacggtttta tttgacactg taaaggcaaa ttttaaagat gagtttttaa
    18541 gtaatttatc agaggttact gatatagcta aaattgacta tgttgtaatt catcacacag
    18601 aaccagacca tgcaggtagt ttaaaatact tattagatat aaatcctaat atagaagttt
    18661 attgtactaa agctgctaaa ctatacttag atggtcaaat aaatagacct tttaactgtc
    18721 atgtaataaa agatggtgaa attttaaata tcggtaaaag aaatcttaga tttataactg
    18781 ctccattctt acattgggtt gatacaatgt ttacttacat tgaggaggac aagactcttt
    18841 taacttgtga tgcatttggt tgtcactttg caagtgttga tgcagaggta gtgaatagtg
    18901 aagattatct aaaatcagct aaacactact atgattgtat agttaagcca tttgctaaac
    18961 atgttttaag tgctgtagat aaggtggtag gactaaacat agaatttgat actatattga
    19021 cttctcatgg tccaatgctt actaaagacc caatggctgc tgttaaaaga tatgttgagt
    19081 ggtctacaga agctgttaat acaactaatc aaaatcaagt ttctatattc tacttatcag
    19141 cttatagtaa tactttagag atggctaaaa agataaaaga aggacttgat aaagaaggtg
    19201 caaaggctga attatacgat ttagaagata tgacattaac agaaatgcac gatacattag
    19261 tagtgtcaaa agtaatatta ctaggctctc caactataaa caaaactatg gttaaaccta
    19321 tgtgggattt attctctgtt atagacccaa tggctaacca aggcaagata gcaggagtat
    19381 ttggttcatt tggttggagt ggtgaaggta taactatggc tgagacttta cttaaatcta
    19441 tgtcattcaa aatgcctgta gaatctctta agaaaaaatt cttccctagt gaagagacat
    19501 taaaagagtg tatggcattt ggtgcagaat ttgcaaaatt agttaaatag ccattaatca
    19561 cacataatat tatttaaaat aaataatttt atatttaaaa ataaattaaa atggagttgt
    19621 ctcaaaatta atttttctaa tctaatttta agttcaactc cttttttatt ttctaaaatg
    19681 actgatataa tgataaatgc accctgtgcg aaagggtgca ttatttataa tatgttctat
    19741 ttgtacacta gtatatttgt attaattcac atatctagcg tatgctacca tccctcttcc
    19801 agaattagat gccgtttcac caatttccac tttaataatt acattatttt ctttacactt
    19861 ttttgataat tctgctgcag aaaggttctt accagtaaaa tctaaagaaa atggcttatc
    19921 atattcaaaa ggatactcat caggtacacc atctggagct aatgcaacca taccatatgg
    19981 tgtattcata aaccctatta cagtaactgt atgctttgat gggtctaaat ttgaattttt
    20041 gcttgtaaac ttaattgtat ttattgatga gttgattaaa ctacacggaa ctccctcata
    20101 catttcaatt tttggacgta gattatttcc ataaacttca tcaagtattg ccccttgttg
    20161 atctgctatc atagtgtgat tcccaggtcc aactggcgca gaaggcttag ctggcgtagg
    20221 tttcttaaca gttggcgttg gattctgtgt ctttactact tcgccaacag ctggatatgc
    20281 tttcttgtca aatggtaatg ggtgagtaag actcttgtat atgatgtctg ctcctgctga
    20341 tttgttggca tcaatatcta catgatacaa acgtccatcc tcaaaacgaa taagattcca
    20401 ctgatggtca tttgttgtac tatgtacata ataacattca attcccatag catcacataa
    20461 agctttcaag ctcctacaca ttccagaaca agcacctttt ttagtaacca atgtataagc
    20521 agtattggct ccctctgctg cgttccagtt aacatatgtt gtgttgtttt taatgtgatt
    20581 ataagcaacc ctaatcttag catctgtggt catgttcttt gtaattttct tgttcataaa
    20641 gtctgctgtt gcttgtgcta ccgaattaag ttgagcttgt gataactttg gaccatatat
    20701 actgttggtt ccagctacat agcttttcgg tgtctttgca gtaacatctt tagctgtcat
    20761 accataaact gttacactca tacatgaggt taaaaccatc attgcaatca atagtttagt
    20821 agctaatttc ctgatttttt tcatattagc attctccttt ataatatatt ttactttcaa
    20881 ttccctacca ttaattaagt tcattttaga tttaaaatat ggattatcaa catgtatgca
    20941 tagcaattca cgtggtcata gaatatttag atttcttgga aaatctgttc tatatttcct
    21001 atatagttcg tatacaatcc aactcacaaa cctgcatttt tgatatcatc acaataaaat
    21061 gataataatt aatatattca aaaatgttgg tctgtaacag gtatgtcaat tttccaatta
    21121 ttagtaatgg cgagagtgag gagaattgtc aataatacat ttaaaattaa aattgtatac
    21181 acttcataca ttctccccta acaacattat acagattata atttgtatat tcaatacatt
    21241 ttttggaaag tataattata tcaaaatatg tgattatgta tagatacaat ccactatgga
    21301 gaaatataaa agaaaagagt ataacaaaca ataaaaaata agatgattca aattttattt
    21361 tgaaacatct tatttactct acaaattaag attatttggt gaattattta attattattt
    21421 tttattaaag aaattttaaa tcttaatata aaatacgcta ttatacataa taatccaaat
    21481 gcaaatgcta ctggaattaa catctccgat tcaaaataaa agaaatattc taagaaaata
    21541 tctggattta ctatattccc attcttgtct aaaaaatctt ttccattata tcctaaatgc
    21601 tgtataaaat tacttatgtt attataatct gcttccctct catataccat attagcattc
    21661 aatccagaag aacttaaatt agtgtttcca tctttcatat ctattacata tagtctaaga
    21721 gctttgactt tactatactt atctttatca agtatttttt caagttctaa cttatattca
    21781 ccaatctttg tcatatcatg tctttctgcc aattgcttta tttctccatc aagttctttt
    21841 cctaaattat acatattatg ttgtaaacta ttattgtaat accacataaa tccagaaatt
    21901 aaaaatgcaa ttatacttat gtaacctaat acttttttaa accccattac aattgattta
    21961 tgcctatcca atgataaaga tagttctttt attatattac ataattcata ctgcatttca
    22021 tcaccatcat caaatctttc aattgctttt ttacatgctt cttcttcatc taatccttct
    22081 aatttaaatt catttgcaga ttctataaga tggcatctca tttcctgttt taattctata
    22141 gtacttttat tgtcacattt tttatatagt ttatctaaat attcatctat tagtttcata
    22201 aattaatcca cctctcccaa aaattgattc ataacctttt taataaatct ccattcttgt
    22261 ttctttattt ctaaaaaatc tttaccttca ttagttaaat tataatattt tcttcttcca
    22321 cctgaacttt gttcattgct ataataagat ttaattaaat ttttagattc cattctttta
    22381 agtgcaagat acattgttcc ttcttttaat tcaaactcac ttctttctct tacttgcttt
    22441 gcaatttcat atccataaca atctttcttt tctaatatag aaacaattaa tatatcgata
    22501 taacctttta acacttcttt atttaactgc attatgtacc accgcctttt cacctactac
    22561 tctataatgt atagtactta tatttactat aataatacat agtactatat aatgcaaggt
    22621 ttatattcta caatagactc aaaaataata aatagctgta tattaatatt taatctataa
    22681 atactaatat acagctattt atcaaatttt aaaaataaat ttttgtttta ttaatgttgt
    22741 cataacaata tttacttggt tgaaatagta ttacctataa gtttaaatat atataataat
    22801 agacttgatt ctatttcata ttattaaaat agagtaatag ttaaattcta ctactctatc
    22861 tataatctat ttcctaatta tttaatctca aatttagctc ttcatcattt aaatctttca
    22921 taagatttct acaggtacta ggtttattgc aacagaaaga ctagggcatt aaacacttat
    22981 atatctgttt ctttagactg taatattaat attttttaaa tacgttgact tttgcttttt
    23041 ctaacttctc tccatgatag ttctcctcta tcaagagctt ttataaatat ttctgctgaa
    23101 gctagatttg tagctattgg aacatgataa acatcacaaa gtcttattaa tgcttgtata
    23161 tctgtttcat gagcctgaga tgtcaatggg tctcttaaaa aaataactaa atctatttct
    23221 tgtgttacta ttaaagaacc tatttgttgg tctccaccta aaggaccaga tgctaatcta
    23281 tttatattta attcagtttc atccattatt ctttttcctg tagttccagt tgcatatagt
    23341 ccatactttt ttaaaattga ttcataacct atacaaaatc cgaccatagt gtttttcatt
    23401 tggtcatgtg ctactaatgc tatattcata tatctaatct cctcaattta tgtttagatg
    23461 tatttaaatt tagaaattta ttttctttct tctcatacac acatttagta ctaatcctaa
    23521 gtttgctaaa gatgtcaata acgaacttcc tccataactt acaaaaggta atgttactcc
    23581 agttactggt attaacgcaa ccgtcatacc tatattttgg attatctggt aaccaaacat
    23641 tcccataaca ccaaccacta tgagggttcc ataaaaatct tttgcatctc ttgcaattgc
    23701 taaaagcctt aataggaata tcataaataa gattatcaac actgccattc ctattacacc
    23761 aagttcttca cctacaacag caaatataaa atcactatct tgtacaggta aaaaatcttc
    23821 ttgattttga cttccattgt aaagtccttt accagttacg cctccagaac caattgcaat
    23881 cagagattgc ataacttgat agtttccttt tagagttaca tcttctggat ttagaaaagc
    23941 ttctattctt accttttgat ggtctgccat cattaaatac atcagtggca ttgacactaa
    24001 tagtatgatt attcctcttt ttatcaactt tgagctaaga cctgctgtga acagcattgc
    24061 aaatatcata caacaaaata caattcctgt tcccaagtct ggttgtgcaa tcaataatcc
    24121 gataaatgga agagaataaa ctacaacagg cataacttcc tttaacgtat ttaatttatc
    24181 ctttttggat tcaagtatct ttgcataact tagtacaaat gttaatttga ctatttcaga
    24241 tgtctgcaag tcaagtggtc ctaagttaat ccacgaccta gctccacctt ttactgtccc
    24301 aattccaggt aataaaacta tggctaacaa aataagactt attatataaa gcgctttata
    24361 atacctgcct agaaggttat agtcaaaaaa taatatgact ataatcattc ctataccaag
    24421 tacaaaagct aatccttgtt taatcaattg attatatgaa cctgttgaat tagcatgtgt
    24481 tgcactacta agtataacaa gcccaaaaat aaagatagct aatactgtaa ctataagttt
    24541 ccagtctaac tgttttatca acttaattgt cgacttataa ttaatattga tttttttcaa
    24601 agaatcaccg tctttctatc tttaaacata taattaaata aaaggggcat ataccaataa
    24661 ggatatcccc cttttaagca ctaattacat acatctatct tttatattct ttagtggtat
    24721 attagcaact aatgcagata caggtttgtc atcatgctca cctctgcatt tagacatttt
    24781 tatttcaagg ccatcatctt ctatttctgc ataattagct attactttta aaatgtctgt
    24841 ttttatcatc tctaaaagtt gtggtgaaca atctactcta tcatgaacta aaactagctt
    24901 taacctctct ttagcaacag atttactagt tttagcctcg ttagaaaaaa ctctaaataa
    24961 atctaacaca gatgtatcct cctttgctac ttagccatgc taaacatttt tttaagtcta
    25021 ccaaagaatc catcttcaac ttcaagatca agtagaggaa cttcttcatt tagtatcctt
    25081 tttgcgatat ttttgtatgc ttgaccagca agtgacttag aatcaagtat agctggctct
    25141 cctttatttg ttgatataat tatgctttca tcatcaggaa caagacctaa caaatctatt
    25201 gctaatattt ctattatatc ttgtttatcc atcatgtctc cacgcttaac catatcattt
    25261 ctaattctat ttataactaa tcttatctct tttatttcat ttgcttctaa tagacctatt
    25321 attctatcag catctcttac tgctgatatt tctggattag taactacaat agctctatct
    25381 gctccagcta ctgcattttt aaagccttgc tcaatacctg ctggacagtc tattattata
    25441 tactcgaaag attcttttag tttctcacac aggtcaatca tctgctcaac tgagacagca
    25501 tttttatctc tagtttgtgc tgctggtaat aaatatagat tatcaaatct tttgtctttt
    25561 attagagctt gcttaagcct acaagttcct tcaactacat ctactatgtc ataaactatt
    25621 cgattttcaa gacccattac tacatctaag tttctaagtc caatatctgc atccacaact
    25681 actgtttttt tattttctag gcttagcgca gttcctaagt ttgctgcggt agtagttttt
    25741 ccaaccccac ctttaccaga tgttataact ataacttcgc tcataatact accccctatt
    25801 tttctttcta tttgtctaac tttgacaaat agctttcgat tacaattctt ccattactta
    25861 caaaggctat ttctgggcta atttctgatt cactttcata attttcttca tcatctggag
    25921 cttctgcaat attatctgct atttgtaata ttttaggatt aagatttcca gcaacaacat
    25981 atgcaaattc attgccttct gcacctgcat gtacaaaacc ttctatttta cccattacaa
    26041 aaacattacc tcctgctaca accttagcac cagcatttat atctcccata acaactgtat
    26101 ttgattttga aaggactttt gaaccaggtt tcatatcatt caatataact acatcacctt
    26161 caaattcaat attttcacca gatcttaggg tattgacata ttttgttgga aaattactat
    26221 tttcttcaat tttttgatct tcaacaaatt ccacatcaaa tctagaagta attccttctt
    26281 taagttctag aatctccatg tcagttaaac aatcactatt aattttacta attttagccc
    26341 cattaaaaaa gccaacatat gcttccaatt tgtttattat tttttcctgt atttcctcaa
    26401 atggagcttc tctttttata tttactatta tccctctttt attacccttg aactctacta
    26461 gttcttgact acaaatttct cttaaagaca taacaacctc cagagtgata tatcatttat
    26521 attcttcaaa tacgctttaa acccttttat tttttctata taaagctaaa gtttatacat
    26581 agattgagct atctattaat ttgtgactcg aaatttatat tttcgtcaga agaattgtta
    26641 acatcattcg tcttgttgtc atttttacta ttagttggct ctaatcccat ataagttcca
    26701 ataacttctc tagttggtaa aagtgagaat acacttgaat caccttgagg aattacaaat
    26761 acaacagcta tttctgggtc atctgctgga gcaaaagcaa cagtccacgt aaaagaacca
    26821 taatcttgtt taaatctatc tatttggtca tctgttattt ttggatttaa ttcttttata
    26881 gcttttctta gatatgaaga attcacctta tcagtgtcct ctaatctaac ttttactcca
    26941 tcttctaatt cttcctctaa tttctttctt tcttcgtctt tcaaatcttt attttctaat
    27001 ttctttttta tttccttttc cttagctaat gaaagctctt tttctttttc tgctttcatc
    27061 ttatcagcta gtttaatcgc atcatttagg ttgacattat aagatgacat atgacttttt
    27121 aaatattcat actcgttatc tgtaggtatt ttcccacttt tctcagctgt accagttttt
    27181 gctgctacat ctattggaaa atcagcaaaa gcactcttcg ctgtaccttg tcttacaacc
    27241 aatttcatac cttttgttaa ttcttttaag ttatctggat ttttaaaagg tattttttcg
    27301 actttcttct gatcattaat tttaactgat gaataatcac ttgaaacagc tctatcaact
    27361 acagataatt ctactaaatt acctccattt gctatagcag ccacatatct tgatatctga
    27421 gctggtgtat aggcattctc accttgtcct atagctaagt tgaatgtatc tgcagtactc
    27481 cattttgcaa agttaaaata actgaatact gctaaatctg ctacttcttc aattctatct
    27541 tctttaacat ccaatttttt tagcctattc attgtttcaa ctctaccagg agttttcttt
    27601 tctgctgccc agcttacaat ctcattgatt cttttctcat attctttagg atttttttct
    27661 ctagttatat caacaaaatc atttgccatt tctctttcta aatttgactt tagaagagct
    27721 tgtgttgatt tcaatttatc ttctgtgcta ggaactttac ctgctctttc ttctacttca
    27781 tcttgaagcc ctgtattttg gtcaagccca aataattttg catactcaag tattttattt
    27841 gcattcatat ctataccaat gctttttcca tctggccatg ttttacctgt accaattgtt
    27901 gccatatata tattacaaga ctcttgtatt gctttatata agtttgtcat accatggttt
    27961 cctctaccat ggttccatac atagtcacca aaagattttt tacctaacat tataacccca
    28021 gggtcattta tagtaaagtt tggatccaga ccattttcta acgctgccat tgaagttagc
    28081 atcttaaatg aagaacctgg ctgaaattcc ccttgtgtaa ccaagtttaa aagtggactt
    28141 cctgctagta agtcatttgg attttttggt tgaagtgctt tataatcctc tgtagaaata
    28201 ccttttgcaa atttatttgg gtcataatta ggataacttg atgaagctaa tacttctcca
    28261 tttttaacat caatagctat aagagctgct gactgtgctt ttcctgcata tgcactaatt
    28321 ggtttgtccc caaatttact tttaaaagta cctcctttag aagcaacttc gattatctgt
    28381 tttaatgcat tatctgaaac ttcttgtaaa tctttatcta gtgtaagata cacagtatct
    28441 cctgatttag gttttttaga ttcaatttct ttactgattc tacccaatgc atcaacttta
    28501 accattttat aaccatcagt tcctcttaat ctactttcat tactcttttc tactcctgca
    28561 agacctacca tatctccagt ttcataacct ttttgaaggt atgattctat ttgagtggat
    28621 ggcatttttc ctacatatcc taacatatga gaagctaatg acccattagg ataatatctt
    28681 actggttcta ctgctattga aacaccaaca aggtccatag cactttcttc aatttgagca
    28741 atcgtagttt ctcccacatc cttagcaata gttactggat tatattgaga atatcctttt
    28801 gattttatca aatcccttac gaccattatt tttcttgcat cttcatcact caaactttta
    28861 tcaatttcta atgcatcact atttcttact ttttcaaacg cttctttggc actcagttta
    28921 gtttctttta tcttataact agccaaccaa tctctcttat ctctttctgc tgtgaacatc
    28981 catttactaa ctaaaatagg tggataatat ccattttcat ttagttttgc ctgtaatctt
    29041 gtcgcatcca atcttttatc ttcttgagat aatattccag ctgatataag tttgtctacc
    29101 aagtaataaa aactttcctt agcattataa tcatttggaa taccattttc tgatttatat
    29161 tccctaatat ctctgtcata tgtataatag tactttccat tttctacata tataggaaac
    29221 tcatctacat attcttcacc atttctctcc agcaaattta taagttttaa tgatatttca
    29281 tttgctcttg aatgcttatt tgcatctttc ttattaatat cgttacctga aacttgaaca
    29341 gtaaataagt ttttatttcc tgccaacagt cttccatatc tatcttttat ttctcctctt
    29401 ggagcttcta ttgccaactt tttatatgtt ttattctcag ctaactcatt gtaatattca
    29461 tatttaaatg tagtcatata gattattttt actaaaatag ctaaaaatat cacgcccatg
    29521 actatcttaa ttatttttag tctatcaact tgtttatttt cttccatgaa atcaccaact
    29581 aatcttcttt aagttttaaa actgctcttt tagataagcg atatattact aaaccaatta
    29641 aactattcac tattggtgct actagtagac cttttacaaa aagtgttgat atgttgtagc
    29701 tttgataaat tatactagat gtacctatat tgacaattga atcaattaaa ctgcctataa
    29761 aaattaaaac gaaagtaata atataactac ctttatatag ctgatctctc atgtatccaa
    29821 ttgcatatgc aataataaac aaaattaatg catttacacc aaaaattcca ccaacggtta
    29881 tgtctttaat aagccctatt attgctgcta taatcccacc ttctaattca tctaaataaa
    29941 gagagattat ggttacatat ataagaacta aattaaagct tatgccaaaa atatctatat
    30001 aatttgttat actattttct atagtcataa gcacaatccc caacagacaa agtaaaactt
    30061 ttttcattgt ttttatcccc tttatcctat atttcttggt tctatgacta caacgtcatt
    30121 tatattctta aaatcaacat aaggttttac aactacatat tttaatgact tatctttatc
    30181 atcaaccact ttttcaactt cgccaattgg tataccatct gggaagaatc caagacctga
    30241 tgttgttatt atatctcctt gaattacatt atatgatgag tcaaacatat atccttgcaa
    30301 atatccttta ctattataac tatctttatt atctaaagta gtattttgag taattgtacc
    30361 tttagcattg gcatcctttg ctagtttaaa gcttacagat gccttagaat ccaatagtga
    30421 aattgcctta ctataattgt tggaaacttc ataaactatg ccaactaatc cactaccatt
    30481 cataactata ctttcttttt ttacacctga attttttcct gcacctatga caaaactctc
    30541 ataccagttt ccatcatttt taccaacaac acttgctgaa atacttgtcg ccttatactc
    30601 ttcttgtaca aagttcagtg tcttttttaa ctcttctagc gattctgttt tatctagttt
    30661 ggcatttaaa gctatcatat tttttttaag tttttcattt tcttcttcta atttttttac
    30721 ctttttagaa ttatctttaa aatttgctac atctttaaaa ccatttttga taaaagaaaa
    30781 tccatcattt attcccttac ctacacttgt aatagcatct gaagctactc ctaaatttac
    30841 tggactacca ctagaaaatt taccaattga tatacccaca attccaatta aagtgatagc
    30901 aactacgccc gttgctatca ctttaacatt aatccttttt ttctcatttt tgttcttgtc
    30961 aaatctcaag gccatcacca acttctaatt cttagtattc atcattaata ctttttcaaa
    31021 gatttcttgg tcttcaacag atttacctgt tccaagtgca acacaatcaa gaggtgtttc
    31081 tgctatttgt acagacatac cagtttcctg tgtaataagc ttatcaagac ctctaagcaa
    31141 agcgcctcct cctgttagca ttattccgtt ttccattata tctgaggcta actctggtgg
    31201 agttctttct agtgtagatt ttattgcatc tactattgaa cttacaggtt cttttaatgc
    31261 ttctctaact tctgtagagc atatttctat tgttttaggt aatcctgaga ttaaatctct
    31321 acctcttatt tgcatattta tttcttcatc atctttaaat gtagaaccta tgttaatttt
    31381 tacattttca gcagttcttt cacctatcat aagattatat tcttttttta cataagccac
    31441 tatagactcg tcaaattcgt ctccacctat tcttatagat ttagcagtaa cgattcctcc
    31501 taaagatatt acagctattt ctgaagtacc tccaccaata tcaactacca tattaccttc
    31561 tggttcttca acttttaatc cagcccctat agccgctgcc attggctctt ctataaggaa
    31621 tgcatcttta gctcctgctt gtcttgcagc ctcttctata gctctctttt ctacttctgt
    31681 aactccaaaa ggaacacata tagctattct tggacttaca acaccttttt tatcagccgc
    31741 tttttgtata aaatagctaa tcattgattg agttatgtca aaatcagcta ttactccatc
    31801 tttcataggt cttatagcta ctatatttcc tggtgttcta cctatcattt ttttggcttc
    31861 ttcacctact gctaatacct ctttactatc atctcttatt gcgacaactg atggttctct
    31921 aacaacaata ccttgtcctt ttatgtaaac taatgtattt gcagtcccta aatctattcc
    31981 catatccttt gtcatcttat taaaactaaa aaaacctttt ttttctttct ttttttcctt
    32041 agccatgatt ttactccttc ctactattaa gaatcatgtt taaaacattc tcctattatt
    32101 ttatcacata taaagtcaaa ttatcatatt ttctttaaag ctaaagtata atccatctcc
    32161 aataattata tggtctatta tttctattcc aattatttct ccacatttaa taagtcttga
    32221 tgtgatattt ttatcttctc ttgatggttc tacacttcct gaagggtgat tatgcatcac
    32281 tattatctta cttgcacttc ttcttatagc ttctttaaaa acctctcttg gatggactaa
    32341 tgacgagctt aaagtcccta tagatacatc tacatcagat attatctcat tttttgtgtt
    32401 taaaagaacc gctttaaaaa cctctttttt taaatacctt aggctatcca tataatacct
    32461 ctgtatatcc caaggattca ttattttata ctttataggt ttaaaactag ctactctaga
    32521 gcctagttct aaagctgctt taatttgggt tgattttgat aacccaattc catctatatt
    32581 acacagctcc tctattgtca tatcttctaa atgtctaata ccctgaatat ctctatttat
    32641 tatatagttg gctaattcaa tagcattttt attcttgttg ccagttctta aaagtatagc
    32701 caacaactca gcatttgata agctttttac gcctttggca agcatctttt ctctgggtct
    32761 ttcctctggt gccatttctt ttaccttaat ggttgaatta aatgactttt tcagataaat
    32821 cacactccat aaaaaagatt tatactaaaa tattttttta ataggtcgcc taaccttgaa
    32881 attggaagac caactatatt aaaataatct cctctaattt cttcaactaa caaagctcca
    32941 taaccttgta taccataggc tcctgctttg tcaaatgact cattagtttt cagataatcc
    33001 tcaatatcct gctctgataa cgttttaaat ttcacattgc tgattacata gtcaattacc
    33061 tttttatctt cgcacaagtt tattaagcta atacctgtta tgacttgatg ctctcttcca
    33121 gatagtcttt ttaacatatc tcttgcacaa gactcatctt ttggttttcc taaaatagca
    33181 ttgtctaaaa caacaactgt atcagctcca ataacaacat cttcattatg ttcagatgct
    33241 acagacatac ttttttcaaa agctaatctc ataactaaat gttttggtgt ttcaccttcc
    33301 aatataatct catcaatttc atttttaatt atatcaaatc ttacattcgt attctctaga
    33361 atttctttcc ttcttggaga ggctgatgcc aagattatat tcatttattc acctcatttg
    33421 tacgtaattt gtacctattt agtctatcac tatattgtaa aaaattcaac agaaatgtcg
    33481 aacctttttt gttacactat tgttatattt attaccatta gaataaatat acataaaata
    33541 gaggtatgga aattattcaa tacctctgtt ttatgtactc attagagata tggaaattat
    33601 tccatatcct tattttgtcc atattacaaa attttaatag ctttctttgg acatttttcc
    33661 atacataaat ggcatcctac acatttatct gcatctacct tatgtttttc ttttaattct
    33721 ccctctattg catcaaactt acattgtttt ttgcacactg tacatccaac acaaagttct
    33781 tggtcaatag taactttctt tttcttagtt atgtcacctg atattacttt tgtagggcat
    33841 tttgctacac attgcataca acctacacac ttattagggt ctatcttagc tattttgtct
    33901 tcaaatatta ttgcatcaaa tttacaagct tttacacaca ttccacagcc aatacatcca
    33961 gcagtacatt tttccttaac agctttacca aactctttgc tattacactc tacaactact
    34021 tcttgacttt ctggttttgt gattattata cccttaggac aaacttcttt acattttcca
    34081 caatttacac acttttcttc atctattact gctattccat caactataga aatagcatca
    34141 aatttacaag catctttaca tgttccaaga cctaaacatc caaatttaca catcttagca
    34201 cctgagttta aaacatttgc tgctctacaa tctgatattc cttcatactc atatttatct
    34261 tttgcacttg aacaagttcc tttacaaata acttttgcta cttgtttctc acctgcttca
    34321 gcacttattc ccattatttc tccaactttt gcaccaacat ctgctccacc tacagggcaa
    34381 ccattaactg gtgcattgcc ttcaactatc gcatttgcaa gacctccaca acctggaaat
    34441 ccacaacctc cacagttggc tcctggaagt actcctagta tagcttccac tctctcgtct
    34501 acttctacag caaacttttt agatgcaaaa tctagtacta tcccgaagat taagcccata
    34561 attcctaaaa ctaatacagc tgtaagtatc accattttca cccctctttt ttatagcttt
    34621 ataagtcctg taaatcctaa gaaagctatt gacattaaac ctgctgatat aagcgttata
    34681 gggaaacctt taaatgcttc tggtatatca gctaattcta gtctttctct tatacctgcg
    34741 aatattacta ttgctaaagt aaatccagct ccggctccaa atccgtttat tattgtttct
    34801 actaaattat aacttttttg aacattaact agagctatac caagaactgc acagtttgta
    34861 gttataagag gtaaataaac tcctaatgct tgatataaag atggactcat cttttgaatt
    34921 accatttcaa cgaactgaac tatagaagct ataaccaata taaaagctat tgtttgtaag
    34981 aatccagttc cagtttttac taataaaatc tgtataaaat aagttataat tgaagctaga
    35041 gttaaaacga acgtaactgc aactcccatc cctactgctg tatcaacctt cttagaaact
    35101 cccaagaaag gacatatacc caagaattga gatgttataa cgttattaac aagaacgata
    35161 cttaaaaata aaagtattaa attcatttat tacacctcca ctatgctttt ttacttctta
    35221 atttattaaa tcctgcaaat aagaatccta atgttaagaa tgcacctggt ggtaatataa
    35281 atattaatac tggttggaaa gatgctccaa ataatgtcat tccaaataaa ctaccatttc
    35341 caagtaattc tcttactgca cctattattg taagtgcaac agtaaatcca agaccttgac
    35401 ctacaccatc aactattgaa ggcatagctc ctgttttgaa agcaaaactt tctgcacgag
    35461 ctaatattaa acagttaaca actattaatg gtatatatat accaagagcc ttatcaagag
    35521 caggaacata tgcttttaaa agcataccta ctattgtaac aaatgtagct ataactacta
    35581 taaatatagg tattcttatc ttatctggtg taatttttct tattaaagat ataactaaat
    35641 ttgcacatat taaaactgct gctgttgaaa gacccatacc aattccattt attgctgaag
    35701 ttgtaacggc tagtgttgga cacataccta taacttgaac aaatgttggg ttctcatcta
    35761 ttagcccatt tttaaatact ttagctaaat tcataattaa ccctccttat ttattaagag
    35821 cactattgaa aacatctata gcagcattta ctcctgtagt aactgctgta gatgtaatag
    35881 ttgcacctga tattgctaat atttgattat ctgctgttgt acttcctttt gctacttcaa
    35941 gaggctcagc agtttttcct ttgtattgac ccttaaatgc atcatcctta gcttttgctc
    36001 caagacctgc tgtttctgac atattaccaa tgtcaacacc tgtaacttga ccttcagatg
    36061 atatacctac cataacttca atttctccac catatccact tggtttagct tttaaagtat
    36121 atccaaccac ttcagaacca tctaaacctt catacacttc agctataaga ccatctccaa
    36181 ggcctttgta agtatcttcc ttcatttctt taaattcttt tgcttctgga aggactgctt
    36241 ttctaagttc attatttgct tgtatatttc tttgttctat tactggagct gtaacctgat
    36301 tagtagctcc aagagctaat gcagctattg cacttatagc aagtaaagta ccacctaatc
    36361 tcaccatact gttcattatt tagccacctc cccaaatact ctatttctaa caaacttatc
    36421 tataagtgga gcaagacagt tcactaatag tattgagtaa gatacacctt ctggatatcc
    36481 accatacatt cttataacag ttgttataag accagctaat acagcgtata ttatttgacc
    36541 ttttttagtc ataggcgaag ttgtataatc cgtaagcatg aagaatccac ctaacataag
    36601 tcctccagca aacagttgat atattgcgaa agttatatta aatccaccta aaaggaatgt
    36661 taatataaat acagttgcta tgtaaaatac tggtataaca taatttatta tgcctttata
    36721 cattaggtat actccaccta ataataataa tattgctgat gtctcaccta tacatccacc
    36781 aatattccct atcatcatgt cagcaagact aattccattg ctagaaagat ctgccagtcc
    36841 tgctgctcca tttttcaaaa agcttaatgg agttgctgta gtaactgcat ctaaattttt
    36901 acctatccag ttaacacctg gttgagtcca agcagtcatt gctactggga atgatgctaa
    36961 taaaaatgct cttgcagcaa gtgctggatt gacaaagtta catccaattc caccaaatac
    37021 cattttaact actaatattg caaatattcc tcctactaga cacatccacc aaggaagtga
    37081 tgctggtacg ttaaatgcta ataataatcc tgttacaaca gctgaaaaat ctcctatagt
    37141 acttttttgc ttcgtaaatt tttgatataa aaattcagta cctactgtac caagtataca
    37201 aaaaaacata gcactcaaag cattaagtct aaagaagtat actcctgcta ctgctgctgg
    37261 aaggagtgct ataataactt gtttcattat atatgaagta tcttcattac ttctcatatg
    37321 aggagaagat gatactatca acttattttc catcgttttt cccccttaac tttctttatt
    37381 tctgagcagc ttgctttctt ctctttgctc ctatttctct ctttgctgat cttatagatt
    37441 gaagtaatgg tcttcttgct ggacaaataa atgagcaaga cccacattct atacaatcca
    37501 ttgctctatg atattcagct gtgtcatagt catcttttaa agaatatgca cttatgaaaa
    37561 gtggttgtaa gaatgatgga catacatctg tacatcttcc acatcttaaa cagttttgaa
    37621 tatctggagt acgtgattct tcctcatcca aacataaaat tcctgaagaa cctttgttag
    37681 tcgctatttc agtagtatat tgagctattc ccatcatagg tccacccatt ataaccttac
    37741 caatcttctt atcttcttta aatccaccac attgttctat tatttctgaa actaatgttc
    37801 caacttttgt tattaggttc tttggctctt tgatgcaact acctgttatt gtagtgattc
    37861 tttcaaccaa aggcatacct gttttaatag acttagctat ctgtgctgct gtggcaacgt
    37921 tgtcaacaac tgcacctgct gctattggta atccaccaga tggaacttct ttgcctgtac
    37981 acgcataaat aagttgtttc tctgctcctt gtggatattt cacttgaagg ccaacaactt
    38041 cgatttcgct atagtcttta gctacatttt gaattgcttc tatagcatct ggtttattcg
    38101 tttcaattcc tataaatcct tttttgacat ctaatacctt cattaatgct cttaaaccaa
    38161 acacaacatc ttctggattt tcaaccatta atctgtggtc tgcagttaag tatggttcac
    38221 attctgcacc atttaatata actacttctg ccttgctatc tggtggagga gatactttta
    38281 catggttagg gaatgtagct ccacccatac ctactattcc tgcctctttt atgataccta
    38341 ctatatcttc tttgctcaaa tcctctaact gaccttttgg ttgaacactc tcatgtaatt
    38401 cttccttaaa gtcattttcg ataactacac attgagctga acctcctggt acttcatgtt
    38461 gttcaatagc aataacttta cctgatactg aagaatgaac gttacatgaa acaaaacctt
    38521 gttgttcacc tattttttgc ccaaacttta cttcatcacc aacttcaaca ataggtttag
    38581 ctggtgcccc tatatgttgc tgaagaggaa tgtaaactat ctttggagct tgagcttttt
    38641 caagtgcctt tgtgttagag tactcttttc tatatggagg atgtatccct cccttaaaag
    38701 ttaagagttt cattgtttta cccccttatc tataaaaaaa cattttttct gccttctata
    38761 agtatactat atatattaaa aaatcttaac aattgttaaa aaaatatccg tatttttata
    38821 atttatttta taaatcaaca cctctatatt aagtcaaatt gaggaaaagg attgcttaat
    38881 taaacaatcc ttttcatata gctttctaaa gtccaaattt tctgtatttt attttataga
    38941 atttataaac atagagtact cctgcatgga tgataaaagc agacttttac ttacactata
    39001 tttttcttca tttgctgctt ttgaagctgt atcaattttt tcattcacat tctttacata
    39061 ctctattaaa ttatctttaa ataaacgcat ttcagaataa tcaatctttt cagcttcttt
    39121 tgatatattt tgtgatattg cctttctatt tgtcaaaata gtattatatt tttccatatc
    39181 tacattattt tcagcattcg accaaaaact tgattcttct ttaaagtttg ttattaattt
    39241 atttaattct ttagatatac tctctatata agcgtagtta cttgtatact ctaaagacaa
    39301 cataggtgca tctaagtgtg ataaaaatgc atctggaaac acctttctta cactgcttat
    39361 ctgctttcta acatcatttt catcaaaaga ggaataggtc tgtatttttt ttactccatc
    39421 cttctccata actgaaaaag gtatgtcatt attaactaat gatgtctgta tttttttcaa
    39481 atcatcatta ttatctattg cagcaacttg aatagtatac atatcccagc cttctatagt
    39541 agctaatttg acttcttctg gctctttagt gttatttacc gctttttctg gattagtttc
    39601 ttgtttatca tctgaattgg tttgtgattt agattttttc ccttttttta ttgaatttaa
    39661 ttcatcagat atatctttat aagttatatc tgatgaatta tttagaaatg gtattttagc
    39721 cgatacatac tccaatatct tgctatcttt tatttttgta taagaataat agccaattag
    39781 acacaagcaa gcaatcgtta taacatattt acgtaaatca atcttatgtc tattattatt
    39841 aaatcctctg tatatcgttt ttcttctatt cattagtttg tccctcccaa aattatatta
    39901 ttaataaagt atatttttaa gagtcacaat ttatgaatat aaataattat ttcttctaat
    39961 tttttaataa gaaattgtac ttactaaaca aatcttcttg caccaagtaa tactttagac
    40021 caatatgaac tagttaaatt atccacttta accttattag gattagtctg agtaccacta
    40081 caatggataa atttactatt tcctacatat atacctacat gattagttgt tccatcacca
    40141 tcagtgtcaa aataaactaa atctcctggt gcataattcc ccatagaaat tgcacttcca
    40201 aaattagcct gttctctaga aactctagga atagaaacgc ctacagaatg tttaaaaaca
    40261 tactgtgtaa atccagaaca gtcaaattta tcaggccctg aagctcccca ttgatatggt
    40321 attccaataa gagtatatgc aaaatctacg attgttgaac cttttgctgt agatttatct
    40381 gaatttccag taaatgatgg ctttgagtta ctattaggtt gagaattttg gttagatgat
    40441 gaatttggtt tttcttttgt accttcatta gtctcagaaa tataacttgc actcacccat
    40501 ccaattgttc cactcgataa ctttacctta taccaaccat tacttttagc ttttaattca
    40561 acaacatctc caccatttaa ttttcctatt atagaatagc ttgtcccagg accacttctt
    40621 acatttaaac tcacagcaga tgttacctta ccattcttgc cttcaattga ttcttcgcta
    40681 gatggttttt tatcagaatt attagtacta tttgaattac tagaattgtt cgttccaaca
    40741 tcttctgatg ttttagaaat atattggcta ctagcccatc cagtaactcc atttgatagt
    40801 tttattttat accatccatt gctttgttct agtaacttta ctatatctcc attatttgct
    40861 ttaccaacta atgaatagtt agtacctgca ccacttctta cattcagtct agaactcaca
    40921 tttactttac catttccact aatagttgtc ccacttgaag ttggattatt ttgacttgat
    40981 gtaccttcag acgaaccact tgttgatatg tattttgcac ttccccatcc aacaacagaa
    41041 ctcgataccc ttactttata ccatccatta gacttttcta aaatctctac agtttttccc
    41101 ttgtataatt ttgctacctt atcgcaatca gaacttggtc cacttcttat attcaaggca
    41161 cttgctgtta ctgttccctt ttcaagagca cttgcattta tggagctaac agatactgct
    41221 actgccccaa ttcctaaagc tgctatagct tttttcacta ctatcactcc ccccaacaaa
    41281 tttttatagt cataaattca taacattatt atccattttt agtccctaca atttaatgat
    41341 aacttatttt cttattaatt gtaaagaaat tataaacata tccttaaaat tagtgatttt
    41401 taggaagtat ttcaatccaa taattatctg ggtccgctat aaaataaatt cccatacttt
    41461 cattttcaaa acatatgcaa tctaaatctt tatgaagttt ttttgcctca tcaaactcct
    41521 caacttctaa agccagatga aattcattgt ctcctaaatt atatggtcta tcccaatctc
    41581 taagccaagt taattctaat gtatgactag taatgccatc tcctaaataa actaatataa
    41641 aacttccatc ttctgcttcc ttgcgcttta cctctttaag ccctaaagct tttttataaa
    41701 aatctaaact tttttctaaa ttagtaacat tgaaattgtt atgacaaaaa ttaaacttca
    41761 ttttgaaatc actctccaat ttttattttt tttatattat atcattatta taaatttatt
    41821 taaatcatat taagttaaaa atttgaatga tgatgaccaa ttaccaaatc atggtaaatt
    41881 atttaaaaga atatgtcaaa aaaagaataa gctctttcaa atgcataaaa aatttatacc
    41941 caagttatac ttaatcatgc aaattggcag aacttattct ttaaaactct aacttttaag
    42001 tttttcttta ataatataat ttattacttt ttttctaata tcttcagcat tataatcatc
    42061 ttctacttct atatccaaaa gttttgctat tgacctcata tcttctctag tctttgacct
    42121 atagcttgat attaattcat cttttatttt ctctggttct aaaagatatt cttcatctcc
    42181 tcttttgaaa acaacgtatt tttgagcata tgaacttcta ttgtagtata tatatcttga
    42241 tatttttctt aaaatttgat tatatgaaag tcgcttgtta atatcaagtt ttaagtactc
    42301 tgaaaaagca aatagctctt tttttgattt aaataatgct tctttcttta tagttcttga
    42361 tattgaagtt acactttctt gatatgcaca cttttttaac atttttaaat atactctatt
    42421 aagaccaata ctttgattga atttttttat attattatta ataatcttat ccaagttacc
    42481 ttcaaagtat ttttttgctc ctttttgtga tacataactc tcaagttctt tgtgggccat
    42541 atcaagtatc atttttttta aatcctcttt atatccccta gattccatga tactccctcc
    42601 cttagctatt tatagtatat tcaaaaagct caagaaatgt gagtcattac aaaatttttt
    42661 tactttttat gtatatatta atttaaaagg ggagataata gtaatgtaaa atcaaacata
    42721 ctcaatctcc cccattttta gacctctatt actcccccaa tagaggtctt tttttagttt
    42781 atcaatttct attcaattcc ctttagttca aatcctaatt ctgctatcac ttcttttaat
    42841 ttttcaatag atacatcatc tttcatatct acagatgcac acttattttc taaatctaca
    42901 tctaaaactt caataccatc tatatcttct gttaatgcag ttttaagatg gtttacacaa
    42961 tgaccacaac tcataccttc tactaatagt ttcttcttca tttaattacc tccttatacc
    43021 ctataagggt attctatcat atagtttata ctttttaaat agaaattaat catttaattt
    43081 gattcattcg attttatatc taaattagat attccctcat atacatcaaa atcatttgga
    43141 gtaattttac cttttaatct actattactt acaatatagt tgtttctcac agctaaactt
    43201 ataaatgttg cattatcttt tatatatgtc tgtacatctt tgtatgcttt ttttgtttca
    43261 atttcagacg tagaacttgt aagtgcagac atatatccat ttaacttatc atcagtatat
    43321 ccactactcg ctataatact acttgcatct ggtataattg atagtttcca tccaactaat
    43381 gctaaatcat aatttttaga attaagagca ttttccatat ccttatctga cagctgattt
    43441 actgtactat ttattcctat agcttttaag ttttcattta ttatgtttgc agtttttatt
    43501 ctctcactat tatctctgtt tactattatc tttaagttca tttcagaaag acttttcttt
    43561 acttcctctt tttctctatt ttttttctct tcagcttctt ttttgattct atcttcttct
    43621 gcttttttag cttttgcttc ttcttctggc gtaagcttct ttgagttctt tttagctgat
    43681 tttttctgat tttttacttt attgtcattt tgatttactg agtttacatt tgcatattct
    43741 accttagcaa gacactctat cgccttatct ttattaaact ctaaatcctt catttcacta
    43801 ttatagtatt ttgattttga attaagtgga aaattaactg gagtagcatc atccatataa
    43861 ccttcactaa taattctatc tttatctata gagtgtgcaa ttgcttttct aaaattaaca
    43921 tctttgaaaa aaggattatt ataattaaat aatacacact cataatctct tccttgatat
    43981 tttgttatat taaactcttt ttcttgaaac ttacttaaat catttaatgt aacattggtt
    44041 atatcactat caagagccat aaccatagat gtccttgcat cttcattagg caccatacct
    44101 acttttatgt tcttcatggt ttttggaact tcttcatagt aatctttgtt tacagataaa
    44161 accattcctt ctctttctgt atatgattct attttatatt tcccatttcc tatcatatta
    44221 ttattcttgt catttacatc ttttgaatct aaatgatttt gagatacaat tggaaaaatt
    44281 aaactatcaa ttgaaaaagc atatctagct ttaaatttta ttgtaaaatc tttatctgat
    44341 ttaatattca cagaagctat atttttagta aattcattat atggactatc tgcacttttt
    44401 tgaattaaac caatagtata gtttacatca tttgaagtaa cattttttcc atcatgccac
    44461 tttgcatctt ttagctttat atctatactc attccatcct gagctatatt atactcctta
    44521 actaattgag gaattacatt gtagttctca tctatagtaa ataaactatc ataaactaaa
    44581 ttcattatat aaccaacaga cttatcagta ttagttatag gatttatagt ttttggagtt
    44641 accattgtta agtttatata cttagcatct atcgaacttt gactttgtaa acttgaatca
    44701 ctactacttt gttttgtttt agtattacta caaccagcta ccataagagt tatagctaaa
    44761 acgactgtta agacttttat tctcttcatt agttttttcc tttcttgcca tatatcttat
    44821 tataatgttc gtaattattt tttacttttt ctacatattt tgaagtttgc ttaaaaggta
    44881 tatcatgtag attttcgcca tctttactat attcattatt ttctaaccat tttttcacat
    44941 tacctgaacc accattatat gcagctatca ctaaatctaa tttaccaaat tctttgtata
    45001 acttacttaa ataccaacag ccaagtctta tattagtctc tgggtcgaaa atatccacat
    45061 tttttaaatt tagttcctct gctccccaat ctctagttat gtctaatatt tgcattaatc
    45121 cttttgcttc cttttttgaa acagcagaac tattaaactt actttcggct ttaataacac
    45181 tgtaaactat attttcatct aaattaaatt ctttcgaata cttttctaca tactctgaat
    45241 attttttagg atataaaaat ttatgtatta ctttgctttc cattaatagt gccccaaata
    45301 agattataaa aatagataga atcaatactt tcttactatt cacgccaatt ctccttcatg
    45361 tactcaataa atttatgtgc tttactttct aattcagtta ttgttcccga attatctatt
    45421 atataatcac catatttgga tttttcttcc tgactcatct gtgaatttat cctactaagt
    45481 gcttcctgct cactgcaatt atctctcttt tgtattctac taatttgtac ttcttgttta
    45541 caagtaacta ctaatagctt gtcaaccata tctaaaaaac cactttctac caatattgcc
    45601 gcatctaaca ctactatatt ttcgcctttt tttctcaatt tttctatttc acttattatt
    45661 ttttctctta ttcgtggatg agtcaagtta tttaattcct taagtttttc ttcatcacta
    45721 aaaactattt tcccaagagc ttttctattt agagttccat catcattttt tatactttgc
    45781 ccaaaatgga caaatacttt ttccaataac aacttatcct caaatatctt cctggatata
    45841 atatcagcat ccactatagg aatgttaaga tttctaaata tatttgatag gctgcttttt
    45901 ccacagccta ttcctcctgt aagtcctaat atcaacataa aatcacctac tttgtctcat
    45961 accaagaact acctacattt aaatctacat ctaagtgaac atccatattt acagcatttt
    46021 ccatttcttc ttttactatt ttcttaacta tatctatttc atcatcaatt gcttcaacta
    46081 tcaactcgtc gtgaacttgt agtataagtt ttgatttcaa attgttctct tccaattttt
    46141 tatgaacatt tatcatagca atttttatta tatctgctgc acttccttgt attggtgcat
    46201 tcattgcaaa tctctttcct ctatttcttt ccataaaatt gcttgacttt atttctggta
    46261 tatatcttct tctgtttaaa attgttacag catatccatc ctcactagcc ttttctactg
    46321 ttgtgtccat aaactctttt attttatggt atttagcaaa ataactttcg atatattctt
    46381 tcgcctttgg aacaggtata tttaaatcat cagctagacc aaagtcactt ttaccatata
    46441 taataccaaa gtttacagct ttagctgcac ctctcaattc actagtaaca tcttccatag
    46501 gaacattaaa aacttgtgaa gctgttttgg tatgaatatc ttcatgatgt ttaaatgctt
    46561 ctatcatatt ttcatcctga ctcatatgtg caagaactct tagctctact tgtgagtaat
    46621 cggcatcaac caacttacag ttatcatctg caataaacac ttttcttatt tttctaccca
    46681 tttccatttt tataggtata ttttgaagat ttggttctgt agatgaaatt cttcctgtag
    46741 tcgttatagt ttgattaaat gatgaatgta ttctattact ttctggattt attatattta
    46801 aaagtccttc aacgtaagta gaatttaact ttactatttg tctatactca gttatcttat
    46861 ctattattgg atgcttatct cttaattttt ctaaaacatc tgcattagtt gaatatccag
    46921 ttttagtttt tttaattatt ggaagctcta atttttcaaa taatataaca cccaattgtt
    46981 ttggtgaatt tatattgaat ggctctcctg ataattcata aatttccttt tctaatgtag
    47041 ctattatttc tttaaattca acactcaatt catccaatat acttttgtct acttttatac
    47101 cttcatactc catatgacct aagacttcta ctaaaggcat ctctacatga taaaaaagac
    47161 catccatact catatccatt agacttcttt ccatcatagg aactgtttct ttaactgtgc
    47221 atattatttg acccatatac tctgctaaat cctcaaattc taaatcctca tagtttttag
    47281 atttaacacc ctttcctaat aattcttctt ttgatttaac cttttttgat aaatacttca
    47341 tagctattgc actacaatca tatgaggtag atgaagttga atctattaag tactcagcta
    47401 ttgttatatc aaaatacata ttttctaagt ttatattata tggttttaaa gatatataat
    47461 catcttttaa attatatcca tactttttaa tttcattatt tgaaaatata ctatctaact
    47521 ttgacacttc atttgaatct acataatata ttttttctcc atctacactt ataaaaatat
    47581 atattatatt tttttcaagt atattacctt gtcctctaac agtttttaaa ataacttgtc
    47641 cttttttgtt tacttcatct ataaattttt ctatatcttt taattttaat atttctattt
    47701 tttcttctac gtgttctgtg tcatctgaat cgaccaaatc aactaatctt gataagagac
    47761 ttgtaaatcc aaagtatcta aatttatcta aaagttcatc tttatcataa tcgccaaaaa
    47821 tcatactatc taaatccact tctattggca catctcttat aattgttgca agtcttttac
    47881 tttgaatagc tatttctttg ttttcctcta ttttcttttt tacactacct ttaagcttat
    47941 ctgtattctc tattagattc tctatactag aaaactcttt tataagcttt atacctgttt
    48001 tttcacctat tccaggtact ccaggtatat tatcagactt gtctcccata agacccttta
    48061 aatcgataaa ttgtgttgga gtcatctcat atttttcaat tacagaatta aagttgtatt
    48121 cttctacttc tccaacccct tttttcgtta taagggtagt tgtattatct gaagcaagtt
    48181 gaatagcatc tttatctcca gttactatgt ataccttata tccattttct tctgcttttt
    48241 tagaaacagt acctataata tcatctgcct cataaccatc tatttctagt ctatttattc
    48301 taaatttatc taaaaggtct tttaatggct gtaattgttc tgccaattca tctggcatac
    48361 cctttcttcc agccttataa tctttatatt ctaaatgcct aaatgtaggt gcttttctgt
    48421 caaaagctac acttatatgt gttggtttat atatatctat cattttaaat agcattgtag
    48481 taaacccata tatagcattg gtctttaacc cttctttatt attcatttct ggaagagcat
    48541 aaaaagctct atttattatt gaatttccat ctattataat taattttttt tccaaattat
    48601 atcactccta aaaattatct atttttgtaa catatatatt atataccaat atagtgttat
    48661 ttaatattcc cataataata atagtatatt aaaattaaat atgttgcaaa caatatattt
    48721 ttttgctata ataatataca tgacatgccc gagtggtgga attggtagac gcagtggact
    48781 caaaatccac cggactaata ctccgtgccg gttcgagtcc ggcctcgggc accattaaaa
    48841 actcctaaag ctatttattc aatagattag gagttttttt atttttgatt taaattttaa
    48901 gttatttttt gaaattactg tgtcttttta aaatttatat aattatataa atttatcttc
    48961 tagcattaat ttaaaaacta atttactttt atataatttt ctattttata tcataactta
    49021 ttacaacctt ttatctaatt tattgtatac aacaacacta caaataaatt gaaataaaat
    49081 aagcaatcca agaacaacta aaacccactt gcttattacc attacagaaa atacactcaa
    49141 tatagaaaca ataaatataa gaattacaag aacatagcac atgatttgat tagtaatacg
    49201 tccagcttta tcacgtaaca taattcttct ttcatcattc atctctatcc tttgattttt
    49261 tatcttttct tcataatcta ctgctctttc aggtttactc caatacatat attgaagaat
    49321 catacataca cctggaccta aagcagctcc agataatccc caaataaaag cctcaaatga
    49381 aaactcagta aatgtagcca ataaaacaag taaaattcca caaataaaat atataattcc
    49441 aacatataac atattctttt tcatttttac tcctcctcat aaataaatat ttcttcaata
    49501 ctcatatcaa agtatctagc tatcttaaag gctaagatga tagaaggatt atacctacca
    49561 ttttctaatg aacctatagt ttgtcttgat acttgcaaaa tagaagcaag ttcttcttgt
    49621 tttatgcctc tttcttttct tatttcttct aatctatttt tcacatctat ccccctttaa
    49681 tatctcaact acggaaagtc tactttccat aattatacaa ctatattcca tttatgtaaa
    49741 gcttactttc catatttaca aaaaaataac agactatttt cagcctgtaa ttttagaatt
    49801 tcatgttgtt tattaatttt aatgttattt attaattcca tattatttat taattttaac
    49861 ttggtttctg aattggaatc caaacttctg tagtataatc aggagcattg atatcgccat
    49921 tgggataaag ttcaatatct ggtaaattag catacacata cccagaactt ggtaaccact
    49981 cagtaataat tcttttttgc aattcctgta ttgccagagc atttggcatt ggagaaacac
    50041 attcaaatac tgcccatgtg cctgatggta ttaagtattc atgagtatct tctaatacag
    50101 gcttatctgt tggagcagca atataataat ctaaaccctt actatttgta cacacactaa
    50161 ctccaagcaa tccacaaggt tcattattta ttaactctga aagtttatca attgttccat
    50221 tttttatgca tttagcccac aacttaggaa ctttctcaaa gcactcttct acaatcatgt
    50281 tcatactttc ttttatacca acaatacgaa accctttctt ttctacaata cgatattgca
    50341 tttctatatt tccttttaca taaatgctta atgtcatctt aggatatgct tttaaaacaa
    50401 caccctttgc tctagctgca gatggagaaa tgttatgtat attttgaaaa gctctattaa
    50461 aagatgttgg tgaatcgtaa ccatacttct cagatagttc taaaattttg atgttactgt
    50521 tctgaagttc aaatgcagcc ttagtcatac gtcttcgtct aatatattca gataatggta
    50581 cttctgcaat atatgaaaac attctttgaa aatgaaaggt tgaacaacat gcaatttttg
    50641 ctgcttctgc ataatccact ccactttcga gattttcttc aatataagta atagcttgat
    50701 ttaatttatt tatccattcc atttgatatt acctccaagc aaattataca gtttaataaa
    50761 ataatatacc tctctattca tgcacaaaat tgtaagcatt taaatttata agcatttttc
    50821 aatcaataca ataaatataa aaattgtatt atacaataaa aaagttcaat aacattatat
    50881 tgtaaaatgt tattgaactt tttataaaaa ttaatttaag tgtagttaaa ttaagtatta
    50941 cactatctta tatattacaa tatcctacta tcttatagtc ttctggcact ttataatctt
    51001 tgtctggagt acctaaattc cattttaaat caaacatagt tgcacttatt attgttgcaa
    51061 aataaagcat aactatacca atgtctattt tttcttcata taaattagta tgaccatctt
    51121 ttctaacagc taaaactaca gtgcctccat caactataaa tctccatggt tgtctattta
    51181 atgtagatgg agctaatctt gcatagtgaa atgcatcaag aagtgctctt tcttctaaga
    51241 tttctatact tgcaacattt ccccattcgt tcatataaac aacatcttct acacctagtc
    51301 tagtagaccc cttatctgtt acaacttgca tatcagattt tgaataattt tgcccagttt
    51361 ttgtagcatt taatacttta gcattactta cattttctcc atatccaata gctataattc
    51421 ctgttacctc tttatctgaa ttaattccaa gtttttcttt tacctttttt ccatcttcaa
    51481 aagtaaccca acaagaacca attccaagtt ctgttacttt aaagattata ctttctccta
    51541 tgtaccctga attttcaatg taattatctt ttatgtcaga taatattata atataacttg
    51601 gagaatctat catatttcct ttgtaccctg ctactttatc taaattatta aaaacttcac
    51661 ttctattcat aattcttaca tcaacatcta tttctggaac tagtttctta caagattctg
    51721 agtatttctt aatttcacta agatattctt ctttaatatc tgtgttctta tattctctaa
    51781 cagactttct atttaatatg attgttttat aatccataat tttatcctcc ccaaactagt
    51841 attgtcttaa ttatataccc attaatatat tattttactc atttatttaa taaataaaga
    51901 ttacaatttt gtaattatta tttattaata atattccact tttacattaa taatgaccag
    51961 ttgtgcaaaa tccattgcca accaccaaat aaaaacatat tataaaggta atataaaata
    52021 acaaacaaat cttaacaaaa aattaaactt tttttacacg aaagaaggct tcccgttgcc
    52081 ttctttattt ttataaaaaa ataagctgtt tctaaaatga tttcacattt ttgaaacagc
    52141 caagttattc tataatgaca actataattt gaggatgtga gggagagttg tcattataaa
    52201 tttagggtaa ttatattatg ttttaagcta gttctttcta tatttatata atacatttta
    52261 tatatgaatt ttatatgaga ttggtataaa tgatatatga aattacatat gtttatatta
    52321 tattaaattt tattattaca ttttccacaa caatactcat atgtctccac attatttgga
    52381 atatttacaa atacaaattc tttacagttc tcacaatact ttaatataga tatagttcca
    52441 caagtgtaac attcaaatat tacacaatcc tcattttcct ctactatttc aaacttttta
    52501 ctatgttcac cacactctgg gcacttgtga ttatttacat tcataaatac tcctccttat
    52561 tagtatagtt acatgtcaaa aacttaatta atgtattcta tattacttat tatatattct
    52621 ataataaatc atattctaat ataataaaac aaattaaata aaaaaaaaac cataaatttt
    52681 aaatttatgg attaattctt gtaatgataa ctctatttga ggatgtgagg gagggttatc
    52741 attacaatag ggtattatat tatggttttt aagctagtct ttctacacct catatgatac
    52801 atatgctata tgaattttat atgattttta cataaatatt ttatgaaatt taaatttttt
    52861 agtcattttg aaatttgtaa aaagttctct aaaaatccac agcatcataa acagccaaaa
    52921 tttaagtaaa acatcataaa aaaatttgtc caataatttt aacaagtaat ctcacctaat
    52981 tataattatt gacacaaact taaataaaca atctataaat cttctataaa tcttaaactt
    53041 tccccctatt gatacacaat ttctagtttg tcaattttat tttgcatttc taagaaaatt
    53101 tcttcaacag aattgttaaa tatattgcct aaatagattc ttttatcttt ttgaaatgaa
    53161 taagatttta cactaccatc agaagaaata tataaatgac tccactctgc tccatatttt
    53221 gaaaacctct cctttgtatc tttaaacctc atatcttcta tttttattgc tttttctctg
    53281 tctcctctta ctacagtgtg accccttttt attaaactgg ttatttttat atcttctttt
    53341 aatttaatac gtgtatcatc attttttgaa tatactttcc atatcacttt atgacgataa
    53401 ttatctaatt cctttattaa gcttctatca atagtaaaac tatctttagt taccacaatt
    53461 aaatcaaaat ggtctaacat atattgaaat atttctctca tacttttatt ttttaaaata
    53521 tcctcaccaa taacctctat aaatctacag cctttctcat acatgcagtt caataaactt
    53581 gtgatttcag aaaaataatc atttgtatta ttatctccat ctatttctat agtaaagtac
    53641 aaaggagtaa tgtatgattt atttcctgtt atctcaaata cacttgatag tgtctgtata
    53701 tcatcttcaa acgttaagta cacattctca taaaacataa aaaattccat aactttttct
    53761 ttcatattat ggatatttct atatctattg gataatatat ttattatatc gtcagtagta
    53821 tttttcccat cacattcagc cagtataaca atttgcttcc aacttaagct atccacattt
    53881 ccgatacttt ttttatatcc atcttcttcg tcataaatag gaccaattat aatgttttct
    53941 tttggccaca gatgaaccct agttccatct tttaatttcg gatatttatt ttttacagac
    54001 tcataaaatc tacttgtatc acccatgatt ctttactacc ccccatagtt taaatattct
    54061 atgctaaaaa tagcacttta tttttattaa ttcaacaatt attcaaaatt ggtcattata
    54121 tatgtttaaa tggatttaac atcaacctta tttatatgtt attgatgttt atatatgtta
    54181 tataaaatct tatttctcat acttaaatgt aatcttaact atctctggtt tacaattaag
    54241 cctaattaaa acttttgagc ctcctaagcc tttatttaaa atcatagtgc tattatcttt
    54301 ttcatatttt ccccagtcat acttaggaaa gaactctcta tttggagata atacacctcc
    54361 aacaaaaggt attcttatta tacctccatg aacatgtcct gctaaaacca aatctgctcc
    54421 ccattttgca tatttttcaa agaaaaatgg tgtatgtgct aaaagaatgt tatattcatt
    54481 ttcattaact ttacctagat tgtcttctac aaaattgtca cttagttcta attttttgtt
    54541 attagcaaat aaatatggat agcattccaa tggtataatt aaaccatata aattaagatg
    54601 gctattacct ctatatattc ttacagattc attttccata tttattattt tctttgaata
    54661 tagttcctta aaataatcct tatatagatg tttatacttt tttattaaag atttttgttc
    54721 atgatttcca attatatgat atacttcata tttttcaacc aaattatcta ttaaatctaa
    54781 tgcaacttga aaatttttat tttctccatc tactaaatct cctgttataa atataacatc
    54841 tgggtttaat gattcaattt tatctatcaa taccttatta tttttatcaa acaccttatt
    54901 atgtaaatca ctcacttgaa ctattttaaa gttatcaaat tcctttggaa tttttttgtt
    54961 gaaaatagta tattctgtcg tttctatatg ctgagtttca tacttataca gaatatacaa
    55021 taatattaat actaatactg tcattgaaac ctttataatc atattctctt cctctttatt
    55081 ctattttgtt aatattatta taatgctttt atgttttttt taaaacaata acatcatcac
    55141 atacatataa atcttttcga cattataaaa ataagttatc cttttctaaa attttcattt
    55201 attttagaaa aggataacta taaaattatc tataaacctc tatattgtga aatatagttt
    55261 ttcctttatt taaattttta tatatatgct ctaaagttcc atcaaaccta atagaatgtc
    55321 cagactctaa aatataagtt ttcccatcca cattaaggtc aagtttacct tctattacga
    55381 gtacatactc ttctaaaaca tgactgtgtg tagatgaaac atgagtacag ttttcctcaa
    55441 gctcaattat aaaaagttca aaccttcttt gagggctaaa agggtatatt ggatataact
    55501 tcatgttccc tttttgctca acaataggct ctacttcttc tttctttata acctcatagg
    55561 tatttgtatt ttcatttaat agtgtagtaa aatttatttt aaatccagat gaaattttcc
    55621 ataaagtaga tactgtcgga cttgattcac ctctctcaat ctgtccaagc attgctttac
    55681 tgacacctgt catctttgaa gctttgtcta aacttatgcc catttcttgt ctcaataacc
    55741 ttaaattttc tcccacatta ggaaatttat tatccatgtt aaaatcctcc tgatagctat
    55801 ttgtattcta tgatttttac tcctgtaagt tctactatct cttttaattt taacatatga
    55861 ttgttacaaa tttcatcaaa ttcatatata taatcttcaa gccctaatgc cttatattta
    55921 tcgattccaa atttatgata tggaagtaac tccatcttgc ctcctggaac attttgtttg
    55981 acaaataatg cagtatttct tatattttct tcactatcat ttactccata aataattggc
    56041 actcttataa ccatagattt attcaacttt gaaagcctac atatattatc taatataatt
    56101 ttattactta ctcctgtata ttctttatga atattatcat ccatagattt tatatctaca
    56161 aatatgtggt ctattttctc aaatacatca tttaccttat tccaatcaaa atatccacaa
    56221 gtttcaattg caatatttat gcctttatca taaaaaatat caactaattc tcttaaaaaa
    56281 tcaatctgaa gtgtaggttc acctccagaa aaagttatcc ctccattaga ttcaaagaaa
    56341 aatataaaat ctttttcaac ttcctctact atttcttcaa cactcatttc ttcggtcatt
    56401 atacaaatgg catctttaag acataccttg atacactctc cacataaatc acatttatta
    56461 tttatttgcg ctctatcaaa tagtgaactt atattttgag gacaaacatc tatacatcta
    56521 ttacaggata cacatttatc tttcataaca cctaatttta ctatgttact ccaggaatct
    56581 ggattagaac accacttaca ttttaattta catccttcta aaaatatagt agtccttatt
    56641 ccatctccat catttactga aaaatgttgt acttttacaa ctctaccttt tttactcata
    56701 atctacctca taattaaaaa ttgctatgtg aatttctagc tattatagca tcttgcattt
    56761 ctcttgataa attaacaaat tgagtactat atccagcaac tctcactaat aaatctttat
    56821 attcttctgg attttcttga gcttttaata gagtatcatt tgatatcgta ttaaattgta
    56881 catggaatcc tcctaaagca aaatatgatt taatcataga tgttagattt ctaagtcctc
    56941 tttcagtttc caccaaatct tgattcagtc ttaaatttag aagtgttcca ccagtatgaa
    57001 catcatgatt tatttttgat gcagatttca ttgctgctag tggacttgtt gtatcagtac
    57061 caacaaatgg agaaactccc tctgtcaaag gttttgtcgc ttttcttcca caaggagttg
    57121 cgcctacgat ttttccagtt ggtacatagt ttgatatacc cataaatgca ctattaaatt
    57181 tagagccaaa aatatccttg tattttctag tttcagtata ataaaaatca gaaacttcaa
    57241 ttgctaatga atctacataa tcattatcat ttccatactt aggaacatcc aacgcaagtt
    57301 ttcttaattc ttcataacct tcccaatcat tatttagtgc ttttgttaat tcttctaacg
    57361 tagtcacctt atcctcaaat actaattttt ttatagctgc caatgaattt gaaactacac
    57421 ctaaccctat accagttaat acaggaccta tattatattt tgctcctcct ttacttaaat
    57481 caactccctt atccaaacat ccatctacac aagtagataa aaatggtctt ggtaccattt
    57541 ctttatgaat ttgttgagca acagtagttc ctataacaga actttttaca agatatgcta
    57601 attgctttaa aaactcatcc ttaagttctt caaaagaagt aaattctgtg atattttttg
    57661 tatctaaccc cattttttct ccagttaatc tactcttacc ttcattcata gcatattcta
    57721 aagctgctgc aaaattgata tttacggctg aagtccactg tcctgttttt ctaaaatgag
    57781 gaactacaca accacagtta ctccaatctc tagcatcttc tgcatcatat ccatcttgta
    57841 ataacatttg tgcccctgca ctatcgctgt gtatagcagg gaaaccagtt ccttgtttta
    57901 ccaatttagc aactgccatt acgaaattgt ctggtgctcc ttgactcact ctaacactta
    57961 atcctggttg gtgagttttt acactttctg tagcctttaa acacatatat gagatatcat
    58021 tcgttccatc agtaccattt ctctttttac caccaacagt aagattttgg aattgattat
    58081 atcctgcaaa gtaatttgct gtatttgctg atatagtcca tacccattct gataacttaa
    58141 tccaaagtgc ttctatcaat tcttgagctt ctgattcagt tattttacct tctctagcat
    58201 cattttcata atatggatac atatattgat caaatctacc taaatttaat gccaatggat
    58261 tttctgatag aataccacct aattgaacaa accatacaaa ttgtattgct tcataaaaat
    58321 tagttggagg gtttgctggt acattcatac atatctctga aatttttata agttctaact
    58381 ttctcttttc atctgtttct tgcttactca tctcttttgc aagatttgaa tatctttgtg
    58441 ccaatgtcat aataccctgt gcaactatag aaacagattt gtaaaaatct atcttttcaa
    58501 tattttctga aactgatata tctaattctt taattttttt atctgcatct tccttaatcc
    58561 ctttatatcc ttttacaaac aatatatctt gataatctgg tgttacttca ccaactgcct
    58621 gtctccactt agaatcatta tctattattc ctgtatctac taatatctta gctgtatctt
    58681 ctgggattct tgctaagaaa acttcttcca aagattttcc cttccaatat ggaaatattt
    58741 cttttcttat aaattctatt tgttcttttg atattacata tgggtcttga gttcttttat
    58801 caaaagtatc catttctttg tctacccatt gccaagaaaa ctctggtgtc aatatccctg
    58861 ttcttctaaa ttttcctgct gtacctacta ttaattcatt ttcaaagatt tttataggaa
    58921 gttctttaca tgtctccaaa aaagctttag ctcttcttat acagatagct tctccctcag
    58981 tttttttatg tgattctgta aaaattctag ccctttcaca acatatcata ggtttagaat
    59041 taatatattc ttgtctaaat gcttctattc tattagtttg actcatttaa aatccccctt
    59101 tggataatat atactacatt tttgtatgtt ataacatact ttaattatat tatactgtcc
    59161 tttagcataa aatggaagca aaataactta ttttttttca tctaccttga acacctatat
    59221 attaatactt tttttgttaa atttataaaa tctaaaaaaa ttttctatga tatattttct
    59281 atattgttat agttatgtct aatatactaa tgatttgaaa tatcaaattt gtatactaga
    59341 cttagtttta aaaccttagt tgattgttta actttgttaa cttcaacatg tatatccttc
    59401 atataaggaa gctctacaac acctactccc ttattaaagt cttcttcaac catagaaaaa
    59461 atttctttct cagttaagtt cgtatcagtc aatgatttaa ataaattgta tataaattta
    59521 acatatttat cactctcaga taacttatca tcttctggat actctttagc acagagaata
    59581 tctattgtta cttttccttc tttatcgtct tcagacatag aatagaataa acttcgaata
    59641 tttttttcag gtggtttttc agcaccattt atagatacta caaagctacc atctgatttt
    59701 gagttagtaa tactataacc actgtctatt atagctttcg aaaatctttg agataaatct
    59761 ttttttactt cttctctacc tttcgcatca ttaatctttt gtgagtaatt attaaatagc
    59821 tcaatagatt catctttttt atcttcaact tgttctttca atgaatcttt actaatttgt
    59881 tctgagctac ttaagttctt atcagataca ggagacatac accctaccat caatgctaag
    59941 ctaagattta aagccacaat tattgccact ctatttatat tcctttttac tttcatacac
    60001 aatcctccca tcacactaac cgctctaaag tattattcat tgcactagaa tatatttata
    60061 ttttctttat attaaagatt tattattcaa tacatatcac cttcctatcc aattcttata
    60121 acttactatt agtaaaatta taagctcctt aatacagaaa taaggatgtt atcttttgtt
    60181 attaaaagat aacatcctta tttttttgta tcaatacata tgtcccaact ggtaacttaa
    60241 tcgccccaac tgtcagtatc ttggtccaat ggtatatata tatttagtat aaatttatcg
    60301 atactatttt caaataataa ttctccatta tatttttgta aagaagattt aatactctga
    60361 atacctattc catgtacgaa cttatccatt ttgtttgtta acaatatatt tttattaaaa
    60421 gtaagctgat ttagtttact attttcacat ttaagtacaa aaaatgacct tgttatagtt
    60481 cctttaattc taatatattt attaatattt tcatccacta ttttatcaca tgcttctatt
    60541 gcattatcca aaatattaga aaatatgctt gacacatcta taggttttac aaaatttact
    60601 tttgaaaaat ttatagagca agtaaattta attccttttt ttaaacatac ttcactcttt
    60661 tcgttgatta taatgtctaa tatcatattt cctgtattat agatatattt aaatgttttt
    60721 atttcatctt ttaaattgtt aacatattca ttaatttctt tgctattgtt tctaaggttg
    60781 tctatacaat aaatgtgatt atttatatcg tgatatagtt tcttaactcg catatgagat
    60841 tcttgaatac ttaaataatg cgcatattgc atatctaact tattttttat taattcagct
    60901 tgagatttta atctattctc ttttattatt tctttaaaca atagtataag aaatatacta
    60961 ctagctccta ccaattttgg attaacaaaa ttatcaaaat agtatccttc tgaatgtaat
    61021 gacccaaacc gttctaattt ttttaataca taatttacaa gcatattcat tgtattaact
    61081 aataaggcaa ataataaata tacataattt ctcttatctt ggctaattaa ttttatagac
    61141 tttctaaaaa agctaaatat aagatatata agaataatta ttaaattact atatatctga
    61201 atttttatag attctaagta aggtactaat aaagattctt tagatgaaat aacattacct
    61261 gtaattgcaa aaaatagtat tctatatata acagcatcca aacatttata atatacacta
    61321 aatagataaa agaaaatgga atacttaata taacccatct tataaaaata attatagtat
    61381 cctccccaag caataaatgc taatatataa aataaatagt ttatattact aaagtaattt
    61441 cctccattaa ataatctact tatctgaatt ataatataaa taagaaacaa gacaatatag
    61501 aatactattt tttcattttt tttactatcc tttttataaa ttaaaattcc gttcattata
    61561 gaaaactgta taaatataga taaaactact aatagctcag tcataaagtt tagcatattg
    61621 tatcaccaag aaattttaag aatttctcct taacttcttt atatctatat ctactaatag
    61681 gtacctcttc tccactttcc agtattgcag tattaggctt tatattttca acatatctta
    61741 aatttactat aaaactttta tggcatctta taaatttata tggatttaat tctttttcta
    61801 ttttgcctaa actatatttt atatcaaaat tcttgtttat tgtgtgtatt agcatatctt
    61861 ttttttgaac ttctatatat tttatttcat ttaaataaat cttatatgta ttagacttat
    61921 tttttattgt aatatgactt tccttattta tttcaatatc tttgatacaa gttagcacat
    61981 gtttttttag ttcttccaac tctattggct ttagtaaata cctataagct cttacctcat
    62041 aaccttcttg cacataatct attaatgaag ttacaaatat tatttccatt tcattgtcta
    62101 cttctctaat ctttcttgca gtatccattc catttaattt ttccattttt atatcaagaa
    62161 gtaatatatc tatatctttt aaattacttt ccagtaactc ttctccagat atatactttt
    62221 gtatctcata ttctatactt atatctttta atatattctc aaggtaatct tctattaaaa
    62281 gttgtgtttc tttttcatct tcacaaactg ctatcttaat cataaaatgc ctccttacat
    62341 aatttctagt taatacaatt aaaatattta taatatattt aaagataatt ttgtatatct
    62401 gatactttag gataacattt ttaaattatt tttatcaata ctcaatccca tacaactatt
    62461 atttgatatt tcaatttaaa gacagaaatt actataatta aaaacagtac ttactgacaa
    62521 aagaagatgt cttaaaatat taaaaaaata attttaggac accttctttt atttatttaa
    62581 actttttaag ccttaaataa tacattaatc tcctatataa ttgtactgca tataaaatca
    62641 acaatataat ctgtagtaca atagcagtta cagatgctcc ataaccacta tataaatttc
    62701 ttatttcaat attcaataaa tatataaata ttactactaa cataaagaat ataaacatat
    62761 tcataaataa aattgacttt actttatttg ttttatcaga atcactatat aatttaggag
    62821 gtatgtcttt gtattctttc gaccatatat accatgcaga tgtacccata aaactaccaa
    62881 tactcctaaa tacaagattc cagccatttg atttatgttc atcaaaataa ttattctcta
    62941 catcatagta gtaatcaaca gtgtatttta tttttcttgg acttccctta tgaaaataaa
    63001 atattcctcc aaatttattt atcttatata aattatatcc tttagcttca atatcttcta
    63061 accatttctc tatcttatca ggtgaactat accagtcaaa tttgaatttt attttctttt
    63121 ccatagcact cattctccaa aatgatattt ttaaatagct taaaaatcta tttaaataat
    63181 tatatcattt tgatactaat tttaggttac aatcatatat ttaaaagtta tttaaatagt
    63241 aataaactaa tagccataac acccattcct gcaatcaatc cataaataga taaatgatgt
    63301 tccccgtact ctctagctga tggcaataat tcatctagtg atatgaatac cataattcct
    63361 cctacaattg caaatacaat tccaagagtt atatcattta aaaaatttct aagaagtaca
    63421 tatccaataa tcgctcctaa aggctcagac ataccagata aaaaggaata ataaaaagct
    63481 ttctttttat ctcctgtggc ataataaact ggtacagata cagatatacc ttctggtata
    63541 ttgtgtattg caattgcaat tgctatcgga atagctattg taacatcatc aagagctgat
    63601 ataaatgtag ctaatccttc aggaaaattg tgaattgcta tagccattgc tgtaaatata
    63661 cctgttctta aaagagactt attttttttg atattctttt cttctatatt ctccattttc
    63721 tttatttcat gtggattttc ttcttgtgga attagcttat caataacagc aatgatagcc
    63781 atacctataa aaaaagctat tacagttgac caacttccta atttctctcc catagatttt
    63841 gtcaaagcat cttgtgcttt aggaaaaatt tctatcatag aaacataaat cataacacca
    63901 gcagaaaatc ctaagcttat agaaagaaac ttagtatttg tttttttagc aaaaaatgct
    63961 atacaacttc ctataccagt agataaacca gccaataatg ttatcaaaaa tgcaaatatt
    64021 acattattca aataaatcac cttcttttta attgatattg attatcattt tctttatgct
    64081 atcatatata ttttatatag tcaatattta taaaaaatat acacaataaa aaagcagaga
    64141 tataaactta gtctctgctt tttctttata gtatattaaa attatttatt taagaaatcc
    64201 actgcatatt gcacatataa agcagttcca atttctagag catcttcatc tatattaaag
    64261 catccatgat gatgaggata acaagcacct tttgactcat ttctagctcc tacaaatgct
    64321 agtgcaccag gtgctatatt cataaactca gctaaatctt ctgctcctgt tactttttca
    64381 aatagtgtta tacagtcttc tccaaatagc ttaattgctg catctgtagc tatctttgaa
    64441 cattctttgt catttataac tgctggtgtt aagtacccat actctaattc agcatctgct
    64501 ctatatgctt ctgctgtaga ttttgctata cgttctaaaa ttctaggaat ttgctttcta
    64561 agctctggat taaatagcct tattgtacct tctaagatag cttcactcgc aattacatta
    64621 aatctagttc cagaatttaa aactccaaca ctcacaacta atggttccag aggacttact
    64681 tctctactaa ccatagattg tagattcata actattgctg aacttgcaag cactgcatca
    64741 acaccttgat gaggaagtga accatgacca cctctacctt ttacagtaat tttaaagaaa
    64801 tcagcagaag ccattcttgg tccttcttct accgatatgg tcccagattc tacatcagtc
    64861 caaagatgta ttccaaacac actatctaca ccttccatag caccatcttg aatcatagct
    64921 cttgcacctt taccaacttc ttctcctggc tgaaaaaata attttacagt tccattgata
    64981 ctatccttaa tatcatttaa cacttttgct gcccctagaa gcattgatgt gtgaccatca
    65041 tgaccacaag catgcataag tccttcattt ttagatttgt attctacatc agtgcattca
    65101 acaacttgta gagcatccat atcaccccta agtgctacag tctttcctgg attagctcct
    65161 tttatagttg caattacacc tgtacctcca gctgatacat atggtatccc tattttatca
    65221 agttcttctt taactctctt tgatgttcta acttcttcca tacttttctc aggattttca
    65281 tgaaattccc ttctaagctt aattacatag tctttataac tctttgttat ttctttaata
    65341 tccattccat acctccaagt agtacacatt cttcttattt aaaatacttt ttatcactca
    65401 aatactatat tagatttaca aagatacccg ctattactac agaagctatt gtaactgtag
    65461 taaatcctcc aacaagcatc tttggaagca tcttatccat taaaaattct ttttcttctg
    65521 gtgtttcagc caaagccttt actgcctctt cagttaatat atagtttggt ggaaaaccat
    65581 aaagtgatgt aagcgaaact gaaaaagcca tttctttact ttcacctaaa agcttaccta
    65641 ctataataga gaatattccc atacctatta caccaaatat tatgattcct acaagaggaa
    65701 ctgccatttc aacaagcatt gctggtgtag cttttgctaa ccctgcaaat ataaaagcca
    65761 tcaatgatgt cattaaccat ccaaatgaac cagatttatt aagtggtttt ctatcaacta
    65821 ttccaagttc tgatgctatt acaccaaata ttaaacatat aacatatctt gatacaactt
    65881 catttgtaag atttgtaaat tgtactgcta accatgctac aaatcctaat ctaagtatta
    65941 tcatatatgt cgtatcatat ttttctggta agtctggaat tatcttaaat ctgctttttt
    66001 gttcaggtaa atccttaact ttttcttcat ctgtatttac agttactttt ccacttctaa
    66061 agtctgataa aagtcttttt ccttcttttt taagcattaa tgctgtaata ggataacccg
    66121 caaatccttg tgcaacatac atcaaaattg caagtactga taaacttgca agaccttttg
    66181 ctgtagcagc atctgccatc attatagatg caactagccc tccagtaaga ggaggtgtag
    66241 ctattactgc tgtatcccat ccaaatacta ctgtccctaa tgccaaagca cctacacata
    66301 ttcctactat tcctgccaag gctattacta ttgttttcca ttgacctgct aattccttaa
    66361 tactcatcat agttcccata tgagttatta acaaaagcat acctaattga gctaatggtg
    66421 ttcctaaagc ggctaagtcc acaatatttt ctgggaaaaa agtccaaaat cctactataa
    66481 atataattgc tgatacaaaa accgacggaa caaaagcttt agtttttgct gaaactatat
    66541 ctcctatcgt cagtgatact aaaactagac aaaaagctgt tattgcctcc atacaaaatc
    66601 ccccctcata ataaatatat ttttataaaa tgtatgtata gttatccatt attttactac
    66661 ttttgaaaaa catttcaagt caaaattcga tttttttcat aaaattcgat aaattccata
    66721 aattaaagtt agttttctaa attattcttt ttgtaaaaac gttatcccga ccattggcta
    66781 tttaactcta ttcttacaaa gagaattaaa tgtaatttgc aaaaaataaa acataggata
    66841 cattttattc ataaaacatc ttataaatat aaaatgaatt gtctttatga atcttaatat
    66901 atcctatgtt tgtaagttta atgtgtatgt tagctatggt gtaaaatttg tatactagtt
    66961 attgtgtaac ctactatata ctccattttt gtttactagc tcttcatgag tacctctttc
    67021 ttcaattcct ttatctgtca atactatgat ttcatcagca ttttttatag tagtcaatct
    67081 atgtgcaaca actaaatttg ttctatcttt acttaattcc tctaaagact cttgaatttc
    67141 tctttctgtt acattgtcta aagcagatgt agcctcatcc aatattatta ttggaggatt
    67201 ctttaaaaag attcttgaaa ttgaaattct ttgtttttgc ccacctgata attttacgcc
    67261 tctttctcct atataagtat catatccatc tggcaaagtc tctacaaagt catgtattct
    67321 agctttttta gcagcagcta tcatttcttc atctgtagca ttagggttcc cacaaagaat
    67381 attatctctt atagttcctg taaataaaaa tacatcttgt tgaactatac ctatattttt
    67441 tctcaatgat tttaaactaa catcttttat actctttcca tcaattttta tatcaccctt
    67501 atcaaattca taaaatcttg gcaatagatt acataatgta gtctttcctc ctccagaagg
    67561 tccaactaat gctatagtct taccagcttt tatagataaa cttaaattat ccaaaacttg
    67621 agtcttatct tcatatgtga aagatatatt ttctatctca atgtcacctt ttacattttc
    67681 aagttcaata ggatttttag cttctttttg atggtcttgt tccattatct ctatgaatct
    67741 tttaaaacct gtcataccat tttgatattg ctctgtaaag tttattaatt ttttcatagg
    67801 ttgtataaac atttttacat atagtatata agcagcaaaa tcacccaaag taatctttcc
    67861 tatataagta aaataaccac cagctattac aactacccac tctaagatat ccatgtataa
    67921 attcatacca gagtaatatt ctgccattac cttataagaa tcttgtcttg ctcttctaaa
    67981 taatttattg cttcttacaa acttatttaa ctcttctttc tcagtacaaa aagacttagt
    68041 taccttcata cctgctatac tattttctaa agtagcattt acatcaccta tagtaactct
    68101 actcttcata aaagcaatat tcatcttatc ttttttagct attgcaaacc aaattataaa
    68161 cggtaatata gcaaatatta taagcgtaag aggaatattt atatctataa gtataaagaa
    68221 tgaaccaacc aacattacta tagaaatgaa taaatcttca ggcccatgat gtgcaagttc
    68281 tgttatatcc attaaatcat ttactattct agacatagtt actccagatt tgttattatc
    68341 aaaatacgta tttggaagtc tttgtaagtg tgtaaatacc tcatttctca tatcagcttg
    68401 catatctaca ccaataacat gtccccaata ctgcataaaa tagttaagcc ctgcttttgc
    68461 tataaatata agtataagtg ctactgcaaa aactactaac attcttaagt ttttatttgg
    68521 aacaacgtca tccattatat ttctagttat cataggataa actaaatcac ataaggaaaa
    68581 tagaaaagct gctataaggt ctagtgtaaa aattttctta tatggcttat aatatttgac
    68641 aaattgtttt atcataagta ttaaatccct cctttattag tacttctatt agtacttcta
    68701 aaaaataccc ataaattagt ataacataac aataacttta aatcttttat aaacttacaa
    68761 agtaataaca atctttttca taaaattgaa gatttatatc atatagttgt atacttgaaa
    68821 caacataaaa agagctatat ctctatattt aaaattttat aaagatacaa ctctatattt
    68881 aatactaaat tttttttata aatacaaaac tacttcaatg catttaatat ctttttatct
    68941 aatgctgttg tatttatacc tgttatatat cctgttgcct ttattgtagg tatatcataa
    69001 gttgttggta gtatagtagt agatacgatt aaatcagcac cttcttgttt tgttgaacat
    69061 tcagcaattt tacattgctc aacttctgct tgtatattat tttctttaac caatctttct
    69121 actctgtcac aaactattgt tgatgttgcg attcctgctc cacaggctac taatattttt
    69181 ttcatatatt gtcctcctac aatttcttta atattttata actcaaaata aaattgataa
    69241 atttcttata tctttattta tataaataat tatatcattt tatataagaa gaacatctta
    69301 aaattattct tttaatatgt tttttatttc aacattactt atacttaaaa tttcattttt
    69361 tatacaagac tctatgtact ttgatatatt tttataatca tttaaattaa actgttcaat
    69421 attcaattta tattctatat cactgacaat acctatcaaa tcagacttat tagataaaat
    69481 atcctcatac ttaccttttc tagttacttc caatctttta aatctataat ttttatatcc
    69541 ttctatgata atcaagtcca tatcttcata taattgaatc attttatata atggattctt
    69601 ctcttttagt tcttcaatat atgctactcg tttatctgat attatacaga cttttctcgc
    69661 cccagatttt ctatgtttat aagtatcttt tccttcctca tccatatcaa aatcatgaca
    69721 ggtatgttta ataactccaa cacgataccc ttttttattt aattctttta ttatgccttc
    69781 aatcaacgta gttttaccta ctcctgaata tgagacaact gacaatatat tatacataaa
    69841 attgtgtcct ttcataaaac tatctaataa caacatccac taattgattt tcttttattg
    69901 tctcattctt tttaatctta atcatacaat tacttcttag agttgcagat agtctagctt
    69961 ttgcatcttt cttatcattt agctctacat acaatttacc ttcacttgta tatagttttc
    70021 cacttacaaa tctatcttta tttgaaagtt tattaaattc tcctttaaat atagctttta
    70081 tatgatgtgt tcccttctta tatgttaaat actcaataac aggaactatc acattatcaa
    70141 ataccactat tgctgcatgt ggattaccag aaagaccaaa taatagcttt tctcccaatg
    70201 tacctacata acaagctcca ccaggtttaa tgtttatctt ccaaaataat tctgttgccc
    70261 ctattttttt gaatacatct ggaattaaat ctttatctcc aacagaaaca ccacctgtgg
    70321 taattaaaaa atctacactc tgtaacatat tctttacctt tttttctaaa tccaatatat
    70381 catcagaaca attgcatatt gtatctgctt gtattccaag ttttaataat cttgaatata
    70441 aggtatatct attactatcg tatattttac cattctctaa agtctcattt atatcttgta
    70501 gttctgtacc tgtattcaaa attccaactt ttaaatcatc ataaacagtt actttggata
    70561 ttccaagact tgctaatact ccaataccat catatcctat attctgattt ttattaataa
    70621 tcaattgccc cttttttata tcctcaccct taaatatgta attatcgtat tcctttaatt
    70681 ttatatttaa agttatcata tcacctataa ctgttacatc ttcttttttt attacacaat
    70741 ttgcaccctg tggtatcttt ccaccagtca ttatcttcac tgcttcattt ttatttaata
    70801 ccctattaaa tacatctcct gcatacaaag tccctataac ctttaaattt ctattttcag
    70861 aatttgcatt atatgcataa ccatcatagg gtgacctatc aaatggagga ctatcaattg
    70921 ttgaatatat atcttctgca actaccttat ttactgcatc tataagattt actatcttga
    70981 ccctgtttat tggtaaaaca tttttttcaa taatttttat ggcatcttct aattctatca
    71041 ttttaaatac tccccaatat attttttatt taagatattt ctatgtaata tattatagat
    71101 tataaaagtt ggaaatactt ttatcttata tttaattata actaatagtt atctataagt
    71161 gcagttcaaa ttttataaat ctaataaaaa aactgttccc agctagaaat ttccttctat
    71221 cttgaaacag catcatatgc tttagaatat tttattctaa taaagttcct tttattattt
    71281 ttacaatttt atcactttca atagttttta tagattttat tttgttatcc acaatactta
    71341 ttgtaagtac ctcttttttt aatattttgt tatcttcttt caatctataa ctcttaacta
    71401 ctttactgcc ttcatgatta tatgctgtta aatcataatt cgcatctcct acaatttcat
    71461 ttattctgga atcttcaaca ccaacatact ctcccaggtc aatatgtcta aaattttcta
    71521 gtgatacagc cgatttttca tggtcacttt tttcaatcac tatactagat tcagcatcaa
    71581 tgactgatat accttgtgat gagaaagaat tggtttcaac attgacaact ttattttcgt
    71641 taatatcaac atataaagca cttccatcta gttcatcatt tccagtatat tttggataaa
    71701 ctaatgtcat ataacttgat gtatttatat cttgcattgt atttgattct tttaaaactt
    71761 taggttttat ataataaaat gtattataag gtatacccat attctttata atgtacttat
    71821 aatctttatt cataatttca ttaacatcat tttgaacttt tgtcatagtt ttttgctgtg
    71881 ttgctttact tgctacttga tttttctctt tagtattttc tttatgacat ccaacaagta
    71941 taatacctaa aatagttaca caaactaatg acctttttaa cttcataaat caatcctcct
    72001 ttcttaaatt ttatagtatt tatctatatc tcaatttaca gttatctctt ttttcaataa
    72061 ttatatttat tatattataa aataattata taatatttat ttgaatttaa taagattaag
    72121 aagctaattg taatttttct gtaataaaaa acactttaaa gttgaatttt gaaaattcaa
    72181 tttacgatat ttttattgta agtaccttac aacattatac caaattattc ctaaacaatc
    72241 aaaaactcca tgaatattta aaggttttct attttaaaaa tcacctttga ctattaattt
    72301 atcaaatatg ttataatagt tttagataat ttaaggagga ttaaataatg gattttaaac
    72361 aacttgaagt atttgttgct gttgcaaaac atcagagttt ttcaaaggct gcaagagaac
    72421 tttttttaac tcaacctact gtaagcgcac acatacagaa tttagagaga gagctagaaa
    72481 ctgttcttat aaatagaagc aacaaagtta ttacactcac aaaatctggt gaaattcttt
    72541 atgaacatgc tatatatata ttgaataatt gcaaacgtgc aatttatgat ataaaagaat
    72601 attcaggaaa aatagaaggt atcatagata tagcatgtag ttccatacct gaaacttata
    72661 ttttacctga ttttatgaag agtttttcta tgagttatcc agatgtaaaa ttttccataa
    72721 gccattatga ttctcaatat gctatatcag aaattttaaa tgaacgaata agctttggat
    72781 tagttggttc taaaatcaat aatcctcaaa tagagtacct agacttatta gatgatgaac
    72841 ttgttcttat cactccttca gattttaaaa ttgataataa aaataattgt atcgatatag
    72901 gagaattggc ttatctaaat tttattatga gaaaagaagg gtcaggtaca agaaacttaa
    72961 tactaaacac acttagtaaa aataactttc cagtaagtaa attaaatgta atcgctcatg
    73021 tagaatcaaa tgaggctatt aaggaaatgg ttagattagg tcttggagta tcctttatat
    73081 cgtacatttc agctatcgat tatctcaatg caggtaaaat aaaatgttat aaaataaagg
    73141 atgttgattt tactagaaag tttttcttca tttactctaa aaagaaaact ttttccccat
    73201 tagaagataa atttctaaac agattatgtg agtatttcga aattataata taataacttt
    73261 aataaagtag tgcttaattt tgagtttata actaattaat aagctaatta taactatcac
    73321 ataaatgctt ataaattatt atgaaccatc tttctttttt atttaattta gtcaaaaaat
    73381 ccctcgttca aatgaacttg ggattttttt atttatacta ctccaatagc agccaatact
    73441 atacaaataa tcataactga aattaatatc gtagttgtct ttaccttttt tcctaataac
    73501 caatacataa taccgaatat catagctgga agcatacatg gcattatttg gtctaagtaa
    73561 gtttgaatag gctctgccca ttctccacta cctacattaa cactaagttt taacattaca
    73621 ttagatgcag tcatacctcc aattaccata agccctaaca ttgaagctgc ttccataact
    73681 tttgaaacta tacttgaacc actcacatct ttaaagaatt gagttccata cttaaatcct
    73741 ttatctagac atatatagcg tataataaaa tgaggaacat ttattattaa aaggaataaa
    73801 atcggtccca ttatgttacc ctgagaagct aaagctatac caaccccagc tgctataagc
    73861 tttaatgttc cccagaaaaa tgaatctcct atcccagaaa ctggacccat taaacttgat
    73921 ttaacagcat ttatactatt agcatcaaat tctttattct ttgcattttc ttcttccata
    73981 gctccagata tacctaccaa aagagtactt atatgaggag taactgacat aaattctaaa
    74041 tgtcttttta aagccttaga tttcttttct ttatcatctt tatataatct acggattatt
    74101 ggtgccatca tgtatgcata tgctatattt tgcatacgtt cgtagttcca agatgaatct
    74161 aatgtcaatg accttctaaa acatttccaa aagtctttcc tcgttatttt actatctggt
    74221 gaaattgtct ctaatttctt agaactcgtt gtcatctact attacctcct tctctcctac
    74281 aaagttaaca tatattaaag ctattgctaa tccaaacaat gcaactcctg ttactgttat
    74341 gtttaggtaa gcaaccaata taaatcctaa taataaaaat gctactgttt tcttattaag
    74401 catcattcta gctaacatgg caaaacctat tgctggaatc acgcctgctg caacatccat
    74461 tccatgagtt acatatgatg gtataaatga aagtattttt tctattactg gaacacctaa
    74521 tgaaaatcct atacctacta ttattgctaa tattaattta tttcctatac caaataataa
    74581 ttgcacacgt tctacgcctt caatattccc ctcttctgca taacggtcag caatatgagc
    74641 tccccatgta agtactactg tcattaagaa gttatctata agcaatacta gagttgctat
    74701 aggaactgca agtacaactg ctgctgatac atcttgaccc gttaatatta caaacgctgt
    74761 ggcaataata gaaccagaca caaaatcagg aggattactt gccccaacag gaaatgcacc
    74821 cataaatact aattctaatg ttgaacctat tactatacct gtatgaagat tacctagtgc
    74881 taaaccaaca agtggtgcaa caactatagg tctattatgc attgtagaac ctacaaaact
    74941 atgcatatat gcaaagaatg caattagagt tatcaaaata acttgtgtaa attccatttt
    75001 catcccccta aaattatatt aatttcatta catttgtagc atcatcatca ggaactaatt
    75061 gtacaaatac atttacgcct tctgaatcta actctttaat catctttata tcatcttttg
    75121 atacatgcac tgctttagat atattttcac gattatcatc tgattttgtt ccaccaaggt
    75181 ttatagattt aatagctttt acctctttag caagtctata aacatcttct acagattcac
    75241 aaagtatcaa taagttgtat ttatcagtaa cacctgagtt aagtgctttt atagaatctg
    75301 ctatgctttt cattactaac ttaacattag atggtttagc cattttaagt cctgccattc
    75361 tcaattcatc ttttaataag tcatcacttg ctatcaatat acagtctgta cttaaaaact
    75421 ttgtccatgt aaatgctact tgtccatgta taagtctgtg gtctactctt actaatttaa
    75481 tcattataat tcctccctaa tttttttgat ttcatccatg aatgttttta cgtgttctac
    75541 actaacatcc ccaaaatctt tgtaattatc tttaaagtaa cttcctatta ttgccatatc
    75601 tcctaattta agctgttttt ttgcattttc caatgtaact ccagcagcta taaccaatgg
    75661 gaagtctcct aaatttttac gaaacagttc tattttttcc attgatgttt cttgacctgt
    75721 agcattttct gtaactgcta tagcatcaca tcttgtcatt cctattttta aatcttcttc
    75781 aacatcattt tctgataata ctggctgata tttaaaacgt acgcctccaa ttaaatacgc
    75841 tgggcatttt gaacgttgta atttaaaaaa ctcttctaaa gtagcttcat ctctaggttt
    75901 aacatgacct actacagaat caacctgtat ataactagca ttatattttg ttgccagttc
    75961 aaatcccata gtatcaacat ttaaacagtt tactccatat ggtattgata aattagcttt
    76021 tgatacatat tcaagtattc tttctaaatc ataataatta ccatagtaat tttctaacat
    76081 tattccatct acaccatttt cttcaaagat tgtaatctct tttttagctc tttcaaagat
    76141 atcttctgga gtatctcctt ttaagtgtat cattgctata attggttttt tacttttaaa
    76201 tactgataat attccctttt ttttcataaa ctaaaatacc tcttcttctt ctttaatttg
    76261 taatgtcacg ctttgtattc ctcttctaga ttcttccact aattggtcta tatcttcaac
    76321 tgttaattca tcagaaaacc ttgtaagaag ttctaatacc atattcaaat tcattccaga
    76381 aaataaccta acattatgta gattagttaa tcttaacatt gctgtacata cacttgctcc
    76441 atataagtca gataaaatta tatattcaca ttctttatct tctgatattg ttttttctaa
    76501 ttctaaagca aaatctgaag cactttgtcc agggtacaaa ccatacgaac tgacacaatc
    76561 tgctaaatct cctactatca tttttactgc atttaaaagc ccttttgaaa agtctccatg
    76621 agatgctaat attatctttt tcatactcat cctcctacta aattatagat tatatttctg
    76681 ctgatactgc atatttgtac ttatcacttc ttataaattg ctcattgtaa tataagacat
    76741 cattattttc tgtgtacacc gattgtctta ctttcaatag tggcatatta cttgcacatt
    76801 taagatggtc agaatattct ttgtttgaat gttttacttc aaatatattt tctactcgtt
    76861 taggtaatgt gcttatatta ttagatataa cctccattaa agatttatct tctaattctt
    76921 cttttaataa aaacatgtaa tctattctaa aatagtcaac ttcaaaaata acaggtactt
    76981 catctattaa tctaagtctt ttaatacata ttaccttctc ttctagttca atacttaaag
    77041 cttcagctac ttgcttatct gcttttttta ttaaaacaga gattattttg gtacttggtt
    77101 ttgcattaat acgatgacaa gaattagtaa aactatttcc tgcacatgtt gcttctattc
    77161 tctctggtat tgttacataa gtccctttac cacgtttttt acataatata tcttctttta
    77221 caagttcatt aagtgcattt ctcacagtta tacgacttat attaaattct ttacataagt
    77281 ctccttcaga tggaagttta tctcctggtt tatatatgcc agatgctatt tgttttttta
    77341 tgttgtcata tagttgttga tataaaggaa caaaggaatt tacttctaaa tccatttctt
    77401 ttttttgtct cttttcatcc attttgctca cctccctatg taacattttt ataacattat
    77461 ataacaagtt ctttattaca tattataaca agatgaaatc gttgtcaatt tttttttaaa
    77521 taatttttaa tttgacagta ttttctttta ttttctctag tgtgacaaat tgctattttt
    77581 acataaaaat aagactgttg tacaacagat taaattgttt atacaacagc ctttattcac
    77641 ttattacatt tatattttta cttataaatt tatattaaaa aatgccttat atcccttata
    77701 catttcatat atgtctactt tagagacaat ttcatgtggt gcatgcatat ttaaaactcc
    77761 aacaccacag tctataacct ctgcaccttg atttgccaat atatgggcta tagttccgcc
    77821 tcctccttgg tctacttttc caagttcagc agtttgccat actacatttc ctttattaaa
    77881 aattctcttt acttctgaca taaattcagc attagcatca ttacatccac tctttcctct
    77941 tgaacctgta tacttagtta aaactactcc atttcccata tatgccgaat ttctcttttc
    78001 atatgcttct ccaaaatttg ggtcatatcc agcagaaaca tcagctgata ataccttact
    78061 atttgctaaa gctcttctta ctttaatatc acaataatct ccttctaaag caatcagttc
    78121 agccacagta ttttcaaaaa actttgagtg catacctgta ttccctttag aaccaatttc
    78181 ttctttatct acacataatg caactgaagt aaattctggt tgttcagttt ctagtatagc
    78241 ttttacagca gcatatgaac ataccctatc atcatgccca tatcccaaca ccatagacct
    78301 atcaagccct aaatctctag ccttaccagc tggaactact tcaatttcag cacttaataa
    78361 atcttcttca actatattgt atttctcatt taaaatcttt aatatatttg ctgttatagg
    78421 ttctttttct tcatcttcta aaggaatatt cccaattaat atatttaaag cttctccact
    78481 aattccttct gatagtttct tttgcatttg gtctccagcc aaatgaatca ataaatcagt
    78541 tacacaaaat actgggtcac tatcttcttc cccaatagat atgtccactt ttgttccatc
    78601 atttaatata actataccat gtaaagcaag tggaatagcc gtccattggt atttttttat
    78661 tccaccataa taatgagtct taaaaaaacc tagattactc tcttgataca gtggatttgg
    78721 ttttaaatct aatcttggcg aatctatatg gcttcctata atcttcatac ctttttctat
    78781 ataattttta cctattacaa aaagtgctac tgccttctct ttatttataa cataaatttt
    78841 atcaccacaa cttatgcttc ctttttccat agcttcatct attgaaatat agttattttc
    78901 tttagccaat tttataattt cttttactga aagtctttca gtctttgact tacttaaaaa
    78961 ctccatataa ttgcgagaat attgcataat ttgttcaata gtattttctt ttctttcaaa
    79021 atcccaagca ttcttaaatt cgtactttaa gttcatattt tcctcctact aagttctaat
    79081 ttttattgtt tttcatgtat tgctcatatt cttctggtga aactactttg acactatcta
    79141 gtcttgatct aaagtgggct ctaaagtttt ctaaatattc tttccttaaa atttctcttt
    79201 ctttgatttc atcagcagaa aggattccct ctttattttt ctttgctaat tcattaatcc
    79261 tatctaattt cttcttgtca aacatttttt cctcctaaaa aacctctatt tatttaataa
    79321 aataatttat tgctttttat atctaacttg tttttatatt cacaaaaaaa ctcatctata
    79381 ttatcactta ttatagatat tcccttttct agttcttcca tgcttggacg agctatattt
    79441 atcctaaaga atctatcatc cactagattg tcaaaaaaat aagtccctgg aagcattgac
    79501 actcctttgt ttaacataaa atttgtaaat gcttgagatg tatatcctct tggtaattct
    79561 aaaaaaaagt ttattcctcc acaagatttt ctaactttta atttaccact caatttgtca
    79621 ttaatcaagt tttttgccaa tttatactta tcagtatata tcttctctat atgactcaaa
    79681 taattcttcc aatcaaaatt attcatatag taatacattg atttttgaat taaacctggt
    79741 gttgatatat ctgatgaata tttagcccat aaaacttttt ttaacaactc atttggcatt
    79801 tctacaattc ctatcctaag acctggcata agtatttttg aaaagctttt tatatatact
    79861 actctatttt tatcatcata acttctaatt gttctattgt cctttgattc aaaaacaaaa
    79921 tcacttataa aatcatcttc tattatataa aaatcatgtt cttctgccaa ttctatcaat
    79981 ttcttttttt tatatgttga gtaagatatt ccagttggat tttgaaaatt aggcataatg
    80041 tatataagtc ttggttttat tttttccaac tttaatttta aaatacctat atcaattcca
    80101 tcatctaaca taggtataga tattattttt gcacctctac ttttaaacac ttcaattgct
    80161 ccattgtaag aaggttcttc cataaaaaca acatctgaat aacttataag tcctttacaa
    80221 actatatcta taccttgttg agcacctgat attatttgaa tattttcctt agtagttttt
    80281 atatttccat cacttagata ctctaccatt ttttctctta attcttcaga gccaagacct
    80341 tcatcatatt caaatattga actaccatct ttagataatg ccatatttac agcattttta
    80401 aatgaatcga taggaaacat atcattagat ggattcccat tgtcaaaatg aattaaatct
    80461 tctctttgca caataatctt atttttcctg ttatctatac cgcttttata agaatttaaa
    80521 cttgatacaa aagtaccact ccctataatt ttatatacat atccttcatt ttctaaaagc
    80581 tcgtatacct taactatagt agtgttattt acttgtaaaa aatttgatag ttttcttatt
    80641 ggaggcaatt tttcatgttc tactaactct ttatttatta tcaattcttt tatatgatta
    80701 aatatctgta tatatttagt tgattttttc tcatttaaat ctattctgta tttttccaaa
    80761 tttatcaccg ctcattgtat ttatatttta ttgatgcttt tatgtatatt tgatattatt
    80821 tagtatgtat atataatacc aaaattttta taaaaagggg aaatatttat gttttatgac
    80881 tatcacatgc actcaagttt ctctacagac ggaaaatcta caatggaaca aatggtaaaa
    80941 aaatctattg aactcggttt ggaggaaatt tgtttcacag accatgttga ctatgatgta
    81001 tatgctgatg attctttttc aattgtctat gaagattatt ttaagagttt agagactctt
    81061 caaagcaaat ataaagataa aatatcaata aaaaaaggaa ttgaatttgg agttcaaact
    81121 caattaatgg atacatacaa aaaggaagca catcaatatc cattggactt tataatatgt
    81181 tctatccatg ctatagatac aatggactta taccttggta attattttaa agataaaact
    81241 caacatgaag tttatgaaaa ttactatctt tatttatata atattgttaa gaattataaa
    81301 gattactctg tcttaggtca tttagattta attaaaaggt atgcacctta tgacactgtt
    81361 ttagatgata gactattttc tgatataatt gaagaaactc ttaaacaagc tatttatgat
    81421 ggcaaaggta tcgagataaa tacctcttgt tatagatata atcttccaga cctaacccca
    81481 tctaagtata tacttcaaat gtataaagac ttgggagggg aaatcataac cacaggttca
    81541 gattcacatc atataagtca agttgcatgt gagtttgact acatatattc attactaaaa
    81601 aatatgggat ttaaatatgt atctaaattt aataaattga aaccagaatt tataaaatta
    81661 taaattttta cacctccttg tgaatatatt taaaagataa ggaggtgatt tttttgaaag
    81721 taccttattt agtactatca acagttattt tatttatatc caattttatt gtaagaatat
    81781 ttggtttttt atataaaata ttcttatcaa gagcactagg tgaaacaggt ttaggtatct
    81841 atcatatgat ttttaacttt ttgatgattt gcttagctgt tacaacaaca ggtataccta
    81901 ctgcacttag ttgtctagtt gcaaagagaa aagctttaaa cgatagacac aatactaatg
    81961 ctttatttat atcaacttta tatatatcat ttttcgtagc actaattata tctatagttg
    82021 catctttcaa tagttctttt ttatcactta aatttttaaa agatgctaaa ttaaatctat
    82081 ttatactagc tgtttgtcct gctatagtta taataactct ttcaaacgta ctaagaggat
    82141 attactatgg cataaagaat gtaaaaatcc ctgctattgg acaaatcatt gaacaaattg
    82201 gtaaaatatt atttgttttt ttacttgtta tgtacataaa taataaatct atgaattgtt
    82261 atatagctct attaggtata tcgattggtg agttgagtaa tattatattt atgcttattt
    82321 gcttatggcg agattcatca tttgacaata ggtatattat aagcataaaa gatttttata
    82381 attcttctat ggaaacatta aaaatgtcta ttcccataac ttgtaataga atgtcaaaca
    82441 tacttttgca atctataagt tctatgatga taccatcaag attagcatta tcaggaatga
    82501 cttatcaaca atctttaagt atgtatggta ttgtcagtgg gatggtaatg ccttttatat
    82561 ttttaccttt tactgttggt tcagcgctta ttgtaaattt aataccaact atttcacagg
    82621 aaatggctct aagaaagcgt aagagtgtaa ttaaaaaaat caaatactcc atacttctta
    82681 ctttatttgt aggcatacta tcatcaatat ttttttattt ctttggaaaa gatttatgta
    82741 tattagtatt taaaaataca cttgcaggag aatatctaaa agctatgttt ttagttccac
    82801 tatttatgtc cctaaatcaa actctatctg gcattttaca ttcaataaga aaagaattag
    82861 cttcaagtat aaatactatt actggcatgt taattcaact aatagcttta tatgtatttc
    82921 ttccaattcc aggacttaat atttatgcat acatatacac aatgacgata gtatcaatct
    82981 ttacttgtct attacatact atagtgcttt ttaaatcact aaaatctata cgctagttat
    83041 aaaaacgtga aggctaccaa tgtaaattat acactttggt agccttcctt agatgatttt
    83101 tatttataat ttaaactgtc tatatatcta cctatctatc tgtggcaact tggctttcca
    83161 cttccatgat taggtccaca ttgcgaaaaa tcacatactt tagagaaagt atcaacaagt
    83221 cttggttgga ttggatttgg tgatgctaaa actactattt gttcacttat taatgtgcta
    83281 actgtttctt gtaagcaaag tactaaatct atatcatttg gtataattaa ttcatagaaa
    83341 ggttcacaac attcgttgca ttctaatttt aatatagatt ttcctataca atctacagtt
    83401 aagttagttt gatattcttg tcttaaagta acagctcttc cgtcagctgg caagcatatt
    83461 ggtgctgaaa gtgtgttaaa agtaaattct acataatcaa ctcttctctt acatccacct
    83521 cctgctctaa ctgctgggaa agctaatgca acgaactctg tacatccaca tctacctctt
    83581 agctctagta ctaaattacg aactgctaca gttaatcctc tttgtttata agctactgat
    83641 ttgccttttc cttgtctaca gcactcagag tttctttctc cacaaactgc aaattcaaaa
    83701 gttgtttcac agtttcttcc tactatatct cctaatgggt ctaaatcgaa atcttctaaa
    83761 gttgtcattc ctgtgtctat aacgattcca tcattactta agcatatttt ttctatagtt
    83821 acacttgctt gacctgcact tggaactgaa ccaaatactt ctactacttc tgtttcaaaa
    83881 gttaatggct ctccatttgg tcctgttgca tctgtaaatg tttggaattg catagtatca
    83941 aatattctat tagcctctat tgcaaatggc actgcatttg atacagagaa gtttcttgga
    84001 gatataggat tacagcattc tggtccacat ttgttttcaa aacattcatc tgaatccatt
    84061 tcacatggtt cacaatcaca tttacaattg tcatggcatc cacaattgtc atcacatgga
    84121 ttaggtttgc atggattgca tgggttaggt ttacatggat tacatgggtt gcatggattg
    84181 caatcatcat ggcactcaca cttattatca gtattacatc cattatgatg gtgtgatttt
    84241 ttaaaacctc tcatgtcttc tgaatttatt tcatctgtat acacttcttc ttcattcatt
    84301 gtagacattg gctgattcat cattcttctt ttattttttt tataatcttg catttttcat
    84361 tgccctccct gtaagcgatt cttattaagt ctttggcttt ttgaagccta attaatacta
    84421 tgcttttata atcttaattg ttacttgctt tttgaattta tcaataatta ggcgtattta
    84481 gtagaaaaat gcatattaat aaaaaaagta ctactatttg aaatagtagc actttttttg
    84541 tcccgaaaca ccggtggcta agtaaattca caccctaggc actcccaggt gggtgacttg
    84601 ccagtaacct ttaacgtcca aactaactag gcatgttata atttaccaga cacggtctcc
    84661 cgtatttcat ttgtaggttg aatttaaaaa agccttatcg tatgtttcag gatttcatat
    84721 tattattata taataaattt tgaatttttt aaagtggttt tatatagtaa ttgagataat
    84781 cttattctat cattactttt tcttcctttt ttctttatgt atttagttaa ttatcgtttt
    84841 ttcttagctc tagttttagt atttttttca ttataattgt attcggattc ttgctcatta
    84901 atgttgtata gttcctcatc gtacactata tcttcatcat tttctatatt ttcatagcct
    84961 gtgttcttat cttctactaa ttcatcttca ttatcctcca tttcaccttc atctgttaac
    85021 tcatcatcat ccaattcttt gtcttcacaa tctaattctt cgtcttcata atttaactca
    85081 tcattattgt cttcatcatc attattacta tcatcacctc ttaaaagact tcctaacaat
    85141 ttgagattat tcatactacc aagattgttt atatttgcca aagagctcaa actaaatcca
    85201 ccttcaccaa agtcatctgg taaaaataat tctgcaaata aatctatctt ctttttcatt
    85261 cctatagctt tttcaactga attttttctt ttttctggga atacatctat aatttccttt
    85321 atcatcatat tctttttatc atcactatcc atttttctga aaaaatccgt ttcatcttct
    85381 gtatctacca tatctatatt atttaatttt tttattcctc taactaaatc taaaacactt
    85441 tctattttta ttagtatttt tctttcatct cttgacatgt attttttagt tcttgttatt
    85501 atttccattc ccatttctaa atcttcttca cttaaatcca tgagccttaa acctcttttt
    85561 atatcatttg catcaaacct taaattgcca tgtgtagact gtgaaagttt atcatttgca
    85621 ttttttttgt tttttctaac tctattattt ccttttgatt tatttttatc atcaaatata
    85681 gagatattac cattactcaa tgcaatcact ccaatcaaaa atagtaagtt attcaagaca
    85741 attccccctt atattatata attgccctat attaaagtat gtttttcata ttttaatgtt
    85801 ccatttttaa agctcagtgc atatatatta tctataagaa tttttattta tattatatat
    85861 cactcacaat tcaccacttc aatattattt ctatatataa atagtatgaa tataattcaa
    85921 tatatattta tagaaagggg tttttttatg aaaaaattag atacagagtc attagaaaaa
    85981 atggctaaac aaaaaaatat tgacaaggat aaaatagaaa agatggctga tagttacaaa
    86041 ggaaaatcag aaaatgaact tatggaggaa cttataaaaa taggtaagaa tctagatggc
    86101 agagatgaag tagtatcaaa attcaaagca tttttagatg aaaatcaacg caaaaaactg
    86161 gataatataa tggaaaaaat ctcagatgca gaaaaccaaa gagatactaa accagctaaa
    86221 actaagaagg ctaaacctac taaaggtaag tcaaattcac ctgcaccaaa aaatacacca
    86281 ggtagtcaac aaaaaaaatc taaaagttta tttaagaaaa ctaaaaagtc taaccctcat
    86341 gaatagataa aaataaacta tttaagtaat tagataatta tttttagtta atctattatt
    86401 aaatttgata ttattgacat aaaaaatcag gtagtgcctt aggcactacc tgattgattt
    86461 taatagtttt atttttttct ttctgtaaca ctttctctat caacaattct ataaggtaat
    86521 tctattttct tattttcaat taattcctta tttattaatt ttataaccat tcttattgct
    86581 actgctccca tatcgtatag aggttgatat actgtagtaa gtttaggtct atacattcta
    86641 gctatcttaa catcattaaa tcctgcaaca gatatgtctt ctggaacctt atatccagca
    86701 tcacatatag catttatagc acctatggca gcctcatcac ctgttacaaa agccgcatga
    86761 ggtattattc catcatctaa tagttctttc atactattgt atccactctc ataatcagtt
    86821 ccaccatact taatcaaact cttgtctaat tctatattgt tatttgaaag tgctttctca
    86881 taaccagcaa gtctttccat ttctaaaaca gtatcatctt tactcgtcat tataaaagct
    86941 atcttttcat gacctttctt tataagatgc tctgtcatat caaaagtagc ttcttcgttg
    87001 ctagtactta ctgtatatat atcataattt ctagcagttt tacttatata tgtcgctggt
    87061 attccacaat tttgtatata gttgatatgt tcttgttcaa ctatccatga aatcataact
    87121 ataccttcca cttgttttgc tctcaataga tttatactct taagttcttg ttccttatca
    87181 gagtatgtat tcgctaaaag aatatcatag tcatacattt tagcaacctc ttctatccca
    87241 tttaacacct cattaacaaa agaatctgaa acttctggaa ctattacccc tattaattga
    87301 ctcttctttg ttactaagct tctagcaagt ggatttggta tatatccagt ctcttttata
    87361 acctctaaaa ctttttgttt gacttcatca gttacaggtt ttgaatcatt tataactcta
    87421 gatacagtag atattgacac tcctgcttgt ttagcaacat cttttatcgt tatattgcct
    87481 ttcatcttca tcctccttat tttactaaat ttatctaaaa ctgaaccaaa tttttgaagg
    87541 ttcctatttt aactacattt atataagttt ttattttacc ataaaagcaa gtacatttaa
    87601 atacattata ttttatatta taccctatat tcaacaaatt taataatatt cattcttaat
    87661 ttaaatcata ttaaaaaata aaataaaaaa atgctggtat aaaataccag cattttttta
    87721 ttctaatgat ttaagtatta gcagccgcaa cctacttcac catcaaagaa tccaccacat
    87781 gaacaagtta ttagcaataa tattaagaaa ggtatccatg acattatgtc aatgtctctc
    87841 cagcaatctt caaaagctaa gaataggaag aatagtacta ttatccacca tcctcctcct
    87901 ccaaagcatc cttcttctcc aaaaaatcta tctaacataa caaagccctc ctttttttaa
    87961 taactgtgtt cttattctaa gcatccacca cagcagcaaa gtattaataa aactattagg
    88021 aatggtatcc atgccattat gtcaaattct gcccagctat ctccaaaagc taagaatagg
    88081 aagaatagta ctattatcca ccatcctcct ccaccaaaac atccttcttc tccaaagaat
    88141 ctatctaaca ttatacgtta cctcctgttg atattttgtt gagcttttcg ctcctaacat
    88201 atactatgca tttggtttcc attttgctaa tgtattttta ctattttttt aaatttttta
    88261 atttgaacta aaaaaggtaa aaccataact tgtataagtt actggtttta cctatttaat
    88321 aatcaatatt ttttagcaac aacaaccatc atcgaagtta aataataaca atactattaa
    88381 tataacccat atccatatat tgtcatcgca taataagtct tctaaaatgt ctgtgcataa
    88441 tagtaagaat actataacta ttattatcaa cattttattc ccaaaaaatc cttcgcatcc
    88501 tccaaagaaa cgttccatat tgtcttctaa ttttgtcata actaatcctc cttgaatcat
    88561 taagagacta agttttgtct ctttaattaa atatatgtag taatagacag ataagttact
    88621 tctaaaaagt ttttattgat tagtttattt atttcttttt caccaagttt attgtatcta
    88681 tcaacttcat ccagataatc ttttttctcc tctgatatag tatagattaa actttctatt
    88741 gattttattt tgtactcctt atatctttct atcaagaagg atgtttttga attttctatt
    88801 cctttcttta catgcattaa ccttgatatg tagtcttctt tttcattaga tacataactc
    88861 tccttttcag ctacatcttc aaggattaaa ttggtctcca ttacataatc ctctatacgt
    88921 tgcatatcta aagttattga attataataa aaatttactg ctataagtaa aaacattcct
    88981 actgaagtta gtaatagtcc tacatatttc atagcatttc ctcctaagtt atatttgtta
    89041 tcaataaagt ttattcatca aataatactt tattactaca tttataaaat tttattattt
    89101 tttatagatt ccatattgaa aaattcttga tattatatta aactaacatt aaaattaatt
    89161 aaaactgctt taggaggctt aaaatgtttg agaaaataaa agaaataata gcagaacaat
    89221 taggggtaga caatttagat gagataacta tggaagcatc tttaatggac gacttagaag
    89281 ctgattcatt agatgctgtt gaaattataa tggcccttga agatgaattt ggaatagaaa
    89341 taccagacga ggaagctgag aactttaaat gtattggtga tatatgtaaa tatatcgaag
    89401 aaaacaaata gtatcgtttt gtctacaaat ataaatagtc tgtgtaaact tctacataat
    89461 aaattatatt agagttcgca cagactagat tacatttatt tacaatatat aaaatacacg
    89521 ctcttatatt taatttatat actaagtata taaattactt ttcttcataa aacgtaacat
    89581 tctttattat tatatctata gttccatctt gattttgttt tacagtatac ttcattgggt
    89641 cttcaaaatc agttagattc ccttttatgt caaaaccatt atccgttttt atacttcttt
    89701 ttttaagctt tttctcaacc cattttttat ctatactaaa actttcatca agaccttttt
    89761 cttccatatg ctctttaaag ctatccttta actcgtcatc tttaattgaa ttatcaacaa
    89821 agtcatttat atcaacttca tgtttttcct tcagtgtata atttaatata cttcttacat
    89881 cttcagcttg ctttatatca ttactaagag cattggttat ccaattttca gctgtatttt
    89941 taaatacctt ggtcttgtac ttatcatcat ctattttttt agcatttaaa aattctgtta
    90001 caaacttaga ttctgaccct tctttttcag catccttatc taaaagcctt agatgaaact
    90061 catcatttat accacttaga ctaatcaaag ctccttgctt ttgtcttaaa gtctctggga
    90121 taccaatttc atttgaaacc atttgaatat taaatttatc atccacaaat tcaattgaat
    90181 gagtgtacaa ctttttataa tctaatttca gtattgctac actcttttca tctttaatag
    90241 tgtataaaca aattgccaaa tcacaagatt ctagtgcagc attaattttc ataacgtcaa
    90301 acaagtaaga tgcaatttct ttagaatttt tcaaaaaagt actttcatca tatattattt
    90361 gttcacaaca gtttttaatt aaattgtcat tataatcttt aaaaacacct tttcttaaat
    90421 cctcatcttt tgcaattctt tttatagctt tctggaaaaa accatctact tcttgattaa
    90481 ctttgccttc aaagtcattt aatattggaa catcactatt tttgtccaaa acatgtatta
    90541 taaatttatg tattatcata tatatcaccc cattatctta atttcgatat taactctttc
    90601 atatcctctg gtatatctgc tttaaatttc aatttttctt ttgttcttgg ttgttcaaac
    90661 tctaacttat atgcatgaag tgcttgccta tttattagct cttcatctac ataaccatac
    90721 aactcatcac ctattattcc atgacctata tgagccatat gtactcttat ttgatgtgtt
    90781 ctaccagttt ctaagcttac ttctaataca gttgcatttt ctagtctttc tattacttta
    90841 tagtgagtaa cagatgactg tcctctttca tctattatcc tctttattga atcttctgta
    90901 ggtctataaa ttggctcatc tatagttccc tcattttctt ttataattcc atcaactact
    90961 gttatatact ttttttcaac tttattttca ctcattgctg tagacaaagt atgatgtgca
    91021 taagcatttt ttgctactat aactaaccct gaagtattca tatctaacct atttacaaat
    91081 cttattttta cattttcttt ttgattatct atatagtaac taataccatt tgctattgtt
    91141 ttatcatagt ggctttttgt tgggtgaact accataaacg gaggtttatt caccataatt
    91201 atatcaaaat catcataaat tatctgtaaa tttaaatctt gaggttcaaa atttgctttt
    91261 tcctcgtcta tttttacttc tattaaatca ccactataca cctttaaact cggtttttta
    91321 tatactccat ttactaaaac actcttttcc ctcttcattt ttgataatga cctaactgag
    91381 aaatttagct tgtccaataa aacttctttt aaagtcattt cttcttcatt tgtatacgat
    91441 ataagattat atctttgatt ctctttttta aacaaacttt tacctacttt cttttatatc
    91501 ttcctacttt ttatatcttc aaaatcatga tattatatat tttacactat ttttgtttaa
    91561 tagataataa ttatttttaa ctataaaaac ctgtaagaat aacaaatagt tattcttaca
    91621 ggttaaattc ataattaaat atttaatttg taaatattat aatctaaaac tatctcttaa
    91681 ctattaaagt agttcccatt cctccaccta tacaaagtgt agcaagacca gttttagcat
    91741 ctcttctctt catttcatat aaaagtgtag taagtattct tgctcctgag catcctattg
    91801 gatgtcctat agctattgct ccaccattaa cattaacttt gttcatatct atatttaagt
    91861 ctcttattac agctacagat tgggcagcaa atgcctcatt agcttcaact aaatctatat
    91921 cttcaatagt catattagca gcttctaaag cttttttagt tgctggaact ggtccatatc
    91981 ccattatttt agggtcaaca ccagctgttc cataagaaac tatagttgca agaggctcta
    92041 ttcctagttc ttcagctttt tctttagcca ttactactag catagcagca ccatcattta
    92101 ttcctgatgc attaccagca gtaactgttc catctttttt aaatgcaggt cttaacttag
    92161 caagtttctc cattgtagtg ccaggcttaa tatattcatc tttatctact acagtgtcac
    92221 cttttcttcc ttttataaca acaggaacta tttcttcatc aaattttcct tcagcttgag
    92281 ctttttcagc tttattttga cttgcaagag ctaattcatc ttgttcttct ctagttatat
    92341 tccattgctc tgctatgttt tcagcagtaa tacccatgtg atagttatta aatatgtctg
    92401 ataatccatc ttttatcatt gaatcaacaa aagcagcatc acccattctt gcaccatatc
    92461 tcgcacttgg tactaaataa ggagacatac tcatgttttc agctccacca actaacatta
    92521 tatcagcatc acctaatgct ataagttgag atgccattga aacagatctt aatccagaac
    92581 cacaaactat atttatagtc atagctggtt tttctactgg tattcctgct cctaatgcta
    92641 tttgtcttgc tatattttgt ccaagacctg ctgtaagtac tccccctaaa agagattcat
    92701 ctatcatatc tggagttatg ttagctcttt ttatagcttc tttagctgct gttaccccta
    92761 actctaccgc tgaaactgat ttaaatgctc ctccaaaact tcctactgct gttctagctg
    92821 cactggcaat tactacttct ctcatattca ttacccccat taaattagat ttttcatata
    92881 tccgaaattg ttttttaaac aattttattt aaatttttaa ttcccaaatt cttatttatt
    92941 ataatcatag aatcctatct tagtttttct tcctaattga ttagctctaa ccattttagc
    93001 taaaagtgga tgaggtctat atttagtatc tccaaactca gtatataaaa cgttcattat
    93061 ggctaaaaca acatctaatc cgattaaatc acctaatgct agtggtccca ttggatggtt
    93121 tgctcctaat ttcatagctt catctatttc ttctttactt gcaacaccat ctgcatatat
    93181 accaacagct tcatttatca taggtataag tattctattt actacaaatc caggagattc
    93241 agatacatct actggtactt tattgatact cttagataat tcaaatactg tatcaaaagt
    93301 aacttttgat gttaactgac cacttataac ttcaactaat ttcatcatag gaactggatt
    93361 aaagaaatgc attcctataa ctttatctgg tctcttagta gaagaagcta tttctgttat
    93421 agataatgat gaagtatttg ttgccaagat agtatcttct ttacataatt catctagtaa
    93481 cttgaaaaca tctttcttta tattcatgtc ttctacagat gcttctatta ttaaatccat
    93541 atcttttaaa tcttcatagt tagtagttga actaacatga cttaatattt ctgcttttgt
    93601 agcttcatcc atttttccct tagtaactaa cttagttaaa tttttatcta ataaagctaa
    93661 acatttatct atagcacctt gagttctact ctttaaacat acatcatgtc cacaacttgc
    93721 aaaagtttgt acaataccac ttcccatagt tccactacct attacagcta atttcatagt
    93781 tataacctcc tgttatttta gtatttatat tctgttaact agattaaaat actatttaat
    93841 ctagttaaca gcaaatatat ttttaattag atttttaccc ttttataaag ttagcttctc
    93901 tcttttcaac gaaagctgac attccttctt tttggtcttt agttgaaaaa caaagaccaa
    93961 ataaattaga ttctatatct attccagtat ttatatcagt ttgagcacca agttgtattg
    94021 cttctttaga gtatctaact gcaagctgag catttttagc tattatctta gctaatttct
    94081 caacttcttc tattaaaatg tctggctcaa cgactctatt tactagccct attttttcag
    94141 cttcatcagc ttttataact tgacctgtaa agattaattc ttttgctttt gccattccaa
    94201 ccaatcttgt aagtctttga gttcctccat atcctggagt tattccaaga gttacttctg
    94261 gctgaccaaa tttagcttta gcagatgcaa ttcttatatc acatgccatt gcaagttcac
    94321 atcctccacc taaagcaaat ccgtttacag cagctatcac tactttttta ctattttcta
    94381 tttctccaaa agcttttgct cctaagatac taaaatcttt agcagctaca gcatctaaat
    94441 ctttcatgta tgcaatatct gctccagcta caaatgcctt tccttcccct gtcaatatta
    94501 caacatcaat agtttcatca ttattaatat ctacaaatac ttcataaagt tcttctaaag
    94561 tctttgaatt tattgcatta agggctttag gtctattcat tttcactgta catatatttc
    94621 catctacttc aacagctaca ttctcataaa ctttaacatc acttgtactc ataataccct
    94681 ccccaagaaa ttagttagct aaaacttcac ctttttcttt tgcaacactt aactgactga
    94741 taagttctgg aagcacttta tgaacatctc caactatacc aacatcagca tatttaaata
    94801 ttggagcttc tggattttta tttatagcaa ctataaactc agcatcttcc ataccagcta
    94861 tatgttgtat tgctccagat ataccacatg ctatataaag gtctggtctt acagttttac
    94921 cagtttgacc aacttgtctt gctttatcta accaacctgc atctatagtg gcacgagaac
    94981 cagaaacttc tccacctata atttcagcta attcataaag tatgtctaag ttttcttttc
    95041 cacccattcc acgtccagca gaaactaata tcttagcatc ttctatttta acttgttttt
    95101 tagcttcttt tattacttgt acaacttgaa ctaatttatc agcatcatta aattctacct
    95161 tgaaacggtt aattacagct tctttagttt catcaggttc atttttcttc ataacccctg
    95221 gtctaactgt agacatttga ggtctgaaat ctttacaaac tattgttgcc attatatttc
    95281 caccaaaggc aggtcttgtc attaataata attttgtatc ttcagctact gcaagacctg
    95341 tacagtcagc agtaagacct gtatgtattc tagcagaaac tctaggtgct aaatctctac
    95401 ctattgaagt tgcaccaaat aatacaacta tagggtcagc tgcttttatt gcttcataag
    95461 ctgcttttgt atatggttca gttgtataca ctgctaaagc ttcatcatct actactatta
    95521 cctcatctgc accatagtgt gctaatgtat ctattaaacc ttctacctta ctacctaaaa
    95581 gtaatgcaga aacttttgta tcataatctt ttgctatttc tgtagccttt cctagtaatt
    95641 ctaaagaaac agtttgaatt acattttctc tttgttctat tactactaaa acgttaccca
    95701 ttctttatcc ccccttaaat tatatgatat acttctcttt taatttatct atgataattc
    95761 cagctgatgt tttcgcatct tcattgtata ttgtaccagc tggtttaact gattttgtaa
    95821 atgatttaaa tacactagtt ggagaacctt taagacctaa attagaaggg tcaacttcta
    95881 tatcttttac agtccatgtt tctactacat cattttcgaa agcatcatat attcttccaa
    95941 ctttcatgta tcttggtgtg ttcatatctt taagagttgt tataaggcat ggcattttaa
    96001 cttttaagtc atggcaacaa tcttcaaatt gtctttttac tagtacatat tcaccttcag
    96061 tttttatttc ttcagcatat gttattgatg gaagatttaa atgttcagct atttgaggtc
    96121 caacttgtgc agtatctcca tctatcgcct gtcttccagc tattataata tcaaaatcta
    96181 tattttttaa tgctcctgct aatgctgatg aagttgccca agtatcagca cctgcaaatg
    96241 ctctatctgt taataatata cctctatctg cacccattgc taaagcttct tttaaagcca
    96301 tatctgcttg aggaggtccc attgttataa cagttacatg agcacccatt tcttctttta
    96361 attttatagc ttcttctaaa cctgctttat catcagggtt tattatactt ggtactccat
    96421 ctctaattaa agtacctgta ttaggatcta gtttaacttc tgttgtatct ggaacttgtt
    96481 ttatacaaac gactatattc ataaatcctt cctccatatc tattttaata tcgacctatt
    96541 gtgtatattt taatatttat ctattttaat aattttcctg aaataaccat tctttgaact
    96601 tcactagttc cttcatatat ttcagttatc ttagcatctc tcatcattct ttctactgga
    96661 tagtcacgag tgtatccata tcctccatga agttgtacag cttttgtagt aacttccata
    96721 gctgtttcag ctgcaaataa ttttgccatt gctgcttcta ctccataagg ttttcctaag
    96781 tctttattta tagctgcttg atatacaagg tgtctagccg cttgtacctt aacttccata
    96841 tcagctaatt ggaattgtgt attttggaat tttgataatg gtctaccaaa ttgtactctt
    96901 tcttttacat atttaacagt ttcatcaaga gcaccttgtg ctaaacctaa agcttgtgca
    96961 gctataccaa ttctaccacc atcaagagta gacattgcta tcttaaatcc ttgaccttct
    97021 tttccaagta aattttcttt aggtattctg caatcctcaa atattaattc actcgtagct
    97081 gaacctctta tacccatttt cttttcttta actccaaagc taaacccagg agttcctttt
    97141 tcaactataa atgctgatat tcctttgttc cccttagatt tatcagtcat tgccattact
    97201 acatatatgt caccagctat tgcatttgtt ataaatattt ttgagccatt aagtatgtat
    97261 tcatccccgt ctaaaacagc agttgtttgt tggccagacg catctgtacc agcattaggc
    97321 tcagtaagac caaatgctcc taatttttct ccacttgcta gtggtcttaa gaatttttgt
    97381 ttttgttctt cattaccata ttgatatata ggccatgagc caagagatgt atgagctgat
    97441 aatataactc ctgtagtacc acaaactcta gacaattctt caactgccat tatatatcct
    97501 acagtgtctc caccttctcc accatattct tttggatatg gtatacccat cattcctgct
    97561 tttgccattt tttccactgt ttcataagga aatctttctt cttcatcaag ttctgttgct
    97621 aaaggtttaa cttcattttc agcgaagctt acatatagct ctttaagcat ctgatatttt
    97681 ttagaattta aatccataat agcctcctca gtattttata aatattttat tttcatttat
    97741 taattaaaat ctcggcaaca tctataataa ggtatttgaa tatacgtcga gaaatttata
    97801 accttaatca aactacgctc tatatttata tgtgattata ctaaccaatt atgacattaa
    97861 tttaatcata aattgttaat ttaaaatcaa ctatacttaa aaaaaatctc gctttttgga
    97921 attttgtgaa atttcaagtt agaataagat ttctttcaca ctggttacag ataaaataat
    97981 ttgtttacga tatttatatt agggtatatt aaacattaaa tattgtctgt acatctgttt
    98041 tttagccatg tacagaagat ttttatcgta taaaaattat tttaatagag ctaaataatc
    98101 gtatttttat ctgactattt tttattttta aatatcttac atctataata gtatcactca
    98161 aaggataatt tttcaataat ttctaattat ttttttaaca atatttatta cattttttcc
    98221 acttttttgt cattttttta ttgtttcgaa aaaaaatcag aattttttaa ctttattttg
    98281 gattattagt ttaaattaga ttttcctctt agatttataa atatttacac aaaaaaacta
    98341 cctctgtata gattgtatac agaggtagtt ttttactaat tcctactata gtttactata
    98401 tttttttacc aattcttaca aacatctacc catttttcac acttagaaaa cttctccatt
    98461 tcttcacatg taagttctat tgcagagtta ctactgccac atgcaggaaa tactgtatca
    98521 aatcttttca ttgaatcatc taaatagact tttatagaat tttttaaacc aaatggacag
    98581 actccaccaa tagcatgtcc agtaaactcc aagacttctt ctggtgtcaa cattttagcc
    98641 ttacaattaa attcagcctt atacttctta ttatcaatct tagcatcacc agctgtcaca
    98701 attaaaattg catcatctcc tattttaaat gagagtgtct tagctattct tgctggaata
    98761 accccagctg cttcagctgc aagttccaca gtagcactag attgttcaaa ttctaatata
    98821 ctgtcttcct tgccaaattg tttaaaatac tctcttacat tacttattga cattaaatac
    98881 ccctcctagt ctgaactttt ataaatttca tattattctt aattatatct ataattgatt
    98941 tatttttcaa attattccat aatattagca ttccatgtat cattattttt tccaactact
    99001 agataaagtc cttttgccat tggaatattg acaatatatt ctcctttata ctctacactc
    99061 ataccagatt cattaaagta cctataatca aaatttagtc cttttggaat tacaaaatca
    99121 acataacctt gattatttgg ttttattcca tatttcagag ttctttcagt tatagaattt
    99181 ttttcattaa ataaatctac atttacatat gcagaacact tattcattcc ctttttattt
    99241 tccacacaat tttcaaactt cattttagca ctgtttaatt tataactata tttactatta
    99301 ttgcttattt taaatcttac aatagtacca acatctctac ttctcctgct atcaaaatca
    99361 aaaacaattt cctctaaatg atttatttca taatctttga cacttaccat atctctatat
    99421 actaatttat ttatagctat gaatagtgta aaaatcccca aaataaaaaa tgaaactttt
    99481 ataaacttct tcatttttag tctccttata ttttgtgcta ttgtgctata atattaatca
    99541 aaattttaat aattaaactt attctttttt gaaatcttaa tagaaaaata cattgatatt
    99601 ataaaaatta ttattgttaa aaatgtcata ctatataaat ttatatactt agtattagct
    99661 atatcagtta cataatttga aagatatact cctccaactt tactataatt aaaatgcttt
    99721 acttgatata caatcatact aatcatcttc aaaagacttc catatacaaa gtaaattaaa
    99781 atacttacta taaaaccaca aactttcatt tttccatatc caaacttaaa aattaaaggc
    99841 agtaaaatcg tcaaaattgc taaaaatata tttacagaaa aaaatacatc atttaaaacc
    99901 atatttctaa agaacactag tgatgtcaat ttacttagta aggacacaat tattgttaca
    99961 gaaattatta atcctacacc taataaatat tttgagtaaa ctatatcttc tatactaact
   100021 ggcatactcc ttataaaaat ccttgaatca ttttcataat cacactcaaa cgtatttata
   100081 aatatcaaat aactaacaac aatacttact gtataatatg aaattgaatt aaggaaaaaa
   100141 taaaacacaa aaaatagcaa tatgtacttt aaattacgga taccatctga actaatccct
   100201 attattaaat cttttcttat taaattgaac atcatctcac ctcatttaca taataataca
   100261 ttagttcttc tatagtagga tttttgacct tatgcttatc aatttctatc aataggcttt
   100321 ttactttcaa gctatctcca actttaacaa gtgcctcatt ataatattta tactctttca
   100381 caccaactat gctttcttta attgcttcta actctgcttt atttgcccta attatcttat
   100441 attcttgttc tattaattct ttcttaacag taaaaatctg atttcctcta tttataaaaa
   100501 caagataatc agcaatttta attaaattat cagtattatg agtagaaatt attacactac
   100561 tacttccatt tttcacaaaa tcttgtaaat actgcattat ttcagttctt acaattgggt
   100621 ctataccagc agttggttca tccaaaatca ataacttagc attgtgacta agtgcgcttg
   100681 ataacataag cttttcagat tgacctttag ataaattttc aatatgcata ttttcttcta
   100741 tatcaaactt attaaggtat tcatcaaacc tttctctatc aaaattctta taaaataaag
   100801 aaactatttt tctaaattcc ttaaccttta aatgcggata aaattgtaaa gaatcatata
   100861 caaaaccaat attgttttta aagcttattg gagaattttc aatagtttca ttacaaagtt
   100921 caatttcacc ttcatctgca tcaataatcc ccattataat ttttattaaa gtcgtttttc
   100981 ccgaaccatt tggtcctata atcccaacaa tatccccttc ctttaactct aagtttatat
   101041 tatttaactt gaattttcct aatttttttg tgatattcct tatgctaaac acatcttcac
   101101 ctcttatgca tttttttata cccacctata catattttaa cacattcatt acaaaggtca
   101161 tttataaatt tataaattaa gaattataaa actatgttat aatacaaagt atgaagaggt
   101221 gaatatatga aaagaattat aactataaat acaaaccaat taaataagtc ccttgagact
   101281 aaagaactct taactagaaa acttatcaat gctggctttg aagtgtattc agatatttat
   101341 ccagacacag agcttattat atcaattggt ggtgatggct cttttttaag aacagttaga
   101401 gatttcgatt ttcctgagat tcccataatg ggaataaata caggtcatct ggggtttttt
   101461 cctgatattt taccagataa gattgatagc tttattgaag cttatacaaa aaaagattat
   101521 attattcaag aaatgtcact tcttaatgcg gaagtatata ctactactag tggttctaat
   101581 atgcttgctg taaatgaggt tgttataaga ggagacaagt ctaggactat acacctaaat
   101641 ttaagccttg ataataaaca tatacaaaat tttagtggag atggtatgat tatttctact
   101701 tccacaggtt caacagccta taactattct gctggaggta gtattgttga tataaatctt
   101761 gaacttatgc agattacacc tttacatccg ataaatacca atgcatatag gtgctttaca
   101821 tcaagtataa tatgttcaaa tgaatctgtt ataaagattg caccagaata tagatttgaa
   101881 gattctgtat tgattgtcgt tgatggagtt gagcacagat ttagacaaat cgaaaatata
   101941 aaagttagta tatctgatgc aaaaataaaa ttacttagaa tgtcaaacta tgagttttgg
   102001 catagagtat ctgaaaaatt tttatagact gtacttagga ggatttttaa tatgaaaata
   102061 ggaataatga gtgatactca tggtagctta ctttactttg aaaaagcgtt aaatgtatta
   102121 tctgattgtg atgttttatt acatggtgga gatgtcttat atcatggacc tagaaatgat
   102181 attccagaag gatataatcc taaaaaattt attgagacat taaataaatt agaaaacatt
   102241 gtgattgtaa aagggaactg tgatgcagat gttgaccaga tggttataga acatcctatt
   102301 cagagtcctt atgtcatgag ccaatttggt gaaattagaa ttatattgaa tcatggttat
   102361 atagaatcag aagaagaaat tattgacaaa gcaaagaaaa tgggtggtga catattagtt
   102421 ttaggacata ctcatgtaaa aaaactatac atggatgata atttaatagt aataaatcca
   102481 ggaagtactt ctatcccaaa agatggaagc cattctgtcg caattataga tatcataaaa
   102541 actgatgatg aggatgagct tgaacttgat ataaacttaa ttgacatcaa tactggaaat
   102601 ataataaata tcaatgatta gtaaattttt aataaaaata aaataagctt taatttatta
   102661 aactcataat aaaaacaagt aaaccatttt atttctatct caattagaag tttaagtaca
   102721 ataccttaaa cttctaatta aatagaatct ggtttacttg ttttattata tgctatattg
   102781 aaatataact tagtttactt gcttctatta tatattatat tggagtataa cttagtttac
   102841 ttatttcatt atatattata ctgaaatata acttagttta cttattttat tatatatatt
   102901 gaagtgcaac ttggtttact tgctattatt atatattaat tttgatttac acaatattat
   102961 tgtaaggcta atgcttctgc atatggttta ctatttttac ctccaccaac ttgtacaaat
   103021 ttatcagcct ttactttttt tataaaactt ttctgtgcac tacttaaact tccacttgca
   103081 agtactacag gtgactttgt ttttgatgct aatactccag cagcaagccc atcaactaaa
   103141 tcagcttctc taccacttcc atcttttgca aaatacatat tattaacctt acttgatttt
   103201 ccataaaact tttctaaaac tttcgcatta gtatcttttc tatctgtccc tgctagtctt
   103261 tctgagttta ctaactgtcc ttcaagtttt ttacttatac tgtactcccc acctactatg
   103321 tatgtcttag ttgagttttg tgtaataaaa ttctttgcct cacttcttat gctatcctta
   103381 cctgtatata ttatagctgt attatcactt gcagctgggc ttgatattga agttgcatct
   103441 gccagtccat tatacccatt aaccactgcc acttttgaga cacctaaatc accagtatca
   103501 tctagctgtc tagtaagaag taaagatgtt tcttctctat ctgctccacc gattctactg
   103561 actaatactt ccatatcttc aagagattct tttacacttg atgaaatagc tccttcactt
   103621 ccaattaaaa taacttctgc tggattaagc ctttttattt cctctgttac attatatggt
   103681 atactatttt tatttgtaag cagtattggc gcatccaatt tacttgccaa aggagttgaa
   103741 gccaatgcat ctggcaatga atttgagtta actagaaaca ccctttctga accattattc
   103801 caaccacttt gagatatttt tatcgctgta tcaaatctat cttcaccaat aagtttttcc
   103861 tcctttggag attttctacc ttgaagataa ttgttcatat ctacctgtgc attttgattt
   103921 ttactaatag tgtctgcata tacacaactt ggcaacataa tcccaagtga aagtgcaaat
   103981 gctattattt ttttagattt aattttcaat acaattcccc cttttaaatg ttaataccta
   104041 ttgatattca tactttttat tgatacccta aactaaaaat aattatcttt tataaaaata
   104101 attatctttt ataaaaataa ttacaaaaat agctatacca ttttaagtac aacacaagct
   104161 tataatcagc ttgacttata aagaatgata tagctattat aactttaaat gcttaatttt
   104221 taaatacttt ttaactaaac tctttcagca tatttttcag ctattcttac aattagttta
   104281 gtagctttct ccatagaact aactggtata cactcatttt tcccatggaa gtttaatcca
   104341 ccagtaaata tatttggaca aggtaatcca ttaaaagata atcttgctcc atcagtacca
   104401 cctcttacag gaactaaacg tggttttata cctaattcct ccatagcttc tttagctata
   104461 tcaactataa acataactgg ctcaatcttt tctttcatat tgtaataaga gtcttttaaa
   104521 tccaattcca ctctattatc gtatttctta tttatttttt ctatattctc tatcataata
   104581 gattttctat tttcaaattt ttctttacaa tggtctctaa taatataagc catacttaca
   104641 ttctcgacat ttccacctat agaatttaaa tgccaaaatc cttcatatcc ttctgttgtt
   104701 tctggtcttt catctgctgg gaacatttct gatatttcag cagctatatg tatagcattt
   104761 accattttat ttttagctga acctggatga acatttctac catgtatagt aatggttgca
   104821 tttgcagcat taaaattttc acattcaagt tctccaacta ttcctccatc taaagtatat
   104881 gcatattttg ctccaaattt ttcaacatca aataaatcag cacctctacc aatttcttca
   104941 tctggtgtaa atcctatttt tatatctcca tgcttaattt ctggatgatt tattagatac
   105001 tctattgcag tcactatctc agctatacca gctttatcat cagacccaag tagagttgtt
   105061 ccatcagtga ctattaaatc gtcaccttta aattcttcca actctggaga atcctttaca
   105121 tacgtaataa catttaacgc ttcatttaaa actatgtctt ttccatcata attttctatt
   105181 attcttggtt taatatcttt tccactaaca tcttcaattg tatctaaatg tgatatgaat
   105241 cctatagtat ccacaccatc agtatttcct tttaaagtag ccattatata actattttca
   105301 tctaaactca catcatcaac acccattgtt tttagctctt caactatata cttagctaaa
   105361 actctttgac cttctgaaga tggacagttc tcacactgag aattagatgt tgtatcaaat
   105421 gatacatatt ttaaaaatct ttccactact ttttgtttca cgtatatacc ctctttctta
   105481 ataagattaa tattttttta tttacctgtg aataaaattt tatttttaaa aaaatctatc
   105541 aattattata attaaaaaat atccaccttc ttaagtatat catgcataca taccaaaccc
   105601 aaacaaaaaa ttactccaat tattcctttt acttggattc caataaaaat cgctgctagg
   105661 gtagctaatg gatttagtcc aacatttact gatactagtt taggttcaag tatttctcta
   105721 atcaaagaca aaacaaaaaa tatcacagtc atacttatag ctataaaata attttttata
   105781 aggaaataat aaacaattac tggaagatat attgttatta tacctaggaa tggaattaaa
   105841 tccattaaag ctcctacaaa ccctactatt agaccgtatt tcaatccaaa taaagcaaaa
   105901 cttccccaga ttgcaaaaaa tgttatagcc ataagtattg tataggccct tatatatcca
   105961 acaagtgaaa gccctgcctc tttctttacg ttttttacct tctttctaac atcaacagta
   106021 aacatattat aaaaactatt ttcaatctta tcaaggtctt ttgctataaa gtaggtagca
   106081 ataaacaggg taattataaa tattataata tatggaatag aagtagccaa tccaagtata
   106141 ctagtaagaa gattttttgt aatttgcatt acttcaccac tgaatttgtt tactaattgt
   106201 tctacatcaa aattggctat ttcttgaaat gatttcataa agtcatttat tttatttaaa
   106261 aaatacataa tagtattact tatatcctca ggattagcag atatattatt taaaaatccc
   106321 attaattctt tcattgaatt tattactatt attgtagtaa ctgtactgac tatagccact
   106381 gcaagaaaac ttagaacaag agtagagata cctttattta tacgaaactt attttctaac
   106441 ttttgtgata taggattaat cataagtgct attatagcac ctagaaaaaa tggagctatg
   106501 tatggaaacg ctttgtaaat aaaaataaat aacaatgtat atatacaaaa aaagatagtg
   106561 ttgtttttta atttgtataa aaaattattt tctagtatgc tcatcttaaa aatctccttt
   106621 cttctaattt atatttttat tttgtccatt tcatactagt tttatttgaa tacaaaataa
   106681 aaagaagtgt ataaatataa aa
//
LOCUS       DAMKNB010000005       105123 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.005, whole genome shotgun sequence.
ACCESSION   DAMKNB010000005 DAMKNB010000000
VERSION     DAMKNB010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 105123)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 105123)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..105123
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.005"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            150..1367
                     /locus_tag="PC494_000391"
     CDS             150..1367
                     /locus_tag="PC494_000391"
                     /EC_number="4.3.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine ammonia-lyase"
                     /protein_id="HDF3910921.1"
                     /translation="MMNVTLTDVKEARETIKNIVKRTDLLESVKLSEKTGANVFYKCE
                     NLQKTGSFKLRGACNKIASLTDEEKANGVIASSAGNHAQGVALGAKMTGIKSTIVMPA
                     TAPLAKVSATKGYGAEVVLNGAVYDDAYAKAVEIQKETRATFLHPFNDKYVIAGQGTI
                     SLEIFEQLDNKVDTILCPVGGGGIISGVAVAAKALNPNVKIVGVQTANIPSMKESIKN
                     GKVTTAFNDTTIADGIAVKTPGDLTFEIINELVDEIVVVEETEIAESILFMMESQKIV
                     SEGAGAVCTAAILSGKYVPAKDENVVCIISGGNIDINTLYRIIGVALAKEGRRYSFST
                     IMEDKPGNFAELTRIISENGGNILSANQGKLSAGEALGKQSAEFILETIDYDHIARIK
                     KAIEEKGFKIIEL"
     gene            1462..1842
                     /locus_tag="PC494_000392"
     CDS             1462..1842
                     /locus_tag="PC494_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HDF3910922.1"
                     /translation="MKHEVIHTNDAPAALGPYSQAIKAGNLLFVSGQVPLVPETMEVV
                     EGDVQAQTAQSLKNLKAILAESGADFSNVVKTTVFIKDMNEFGAINEVYAEYFGENKP
                     ARACVEVARLPKDVKVEIEVIAVL"
     gene            2126..2608
                     /locus_tag="PC494_000393"
     CDS             2126..2608
                     /locus_tag="PC494_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HDF3910923.1"
                     /translation="MLNFFKKNKSYKLHAVVSGNSINIEKVNDSVFSKKLMGDGVAII
                     PNSNVVVAPCNGKVTVLTESKHAFGMVSDEGVEILVHIGIDTVSLQGEGFKNEVSQGD
                     TVKKGSPIISFEREKINSQGIDCTTIIIVLNHSEFSEINCMVENEVVAGQDTVIEIMK
                     "
     gene            2629..3444
                     /locus_tag="PC494_000394"
     CDS             2629..3444
                     /locus_tag="PC494_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HDF3910924.1"
                     /translation="MRVVKIFNNNALSTVTNDRKEAILLGLGIGFNKRPGDKVNEDKI
                     EKIYYVQDHMQTKFLELLKNVSPEVMDASQQIISLIPGNEGKFNNKGILSLVEHISFA
                     IDRMKNNVFLPNLMLLDIKMMYSKEFELGVKALEIIYRVCHIHLPEDEAGYIALHFVN
                     LQSNDNLAYDTLKFVKGSIDLIKECYGLELDESSLSTLRFRTHLKFLAQRIFKNEICQ
                     DDKMIEMYDYLINNHPKNKEYLEKLNVYIEKEFRYKLDKPEKIYLLLHLTKIL"
     gene            3495..5045
                     /locus_tag="PC494_000395"
     CDS             3495..5045
                     /locus_tag="PC494_000395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HDF3910925.1"
                     /translation="MKEKLLGGLETFAKAMVQPLMYLSSAGILMVVGVLLTNDMLLGV
                     LPFFKWEPIQIFGSLIYNCIMAIINNLAVIFAIGIPAALAKKEKHKAALIGFMSYIIY
                     LTASNTMLTSLGQLAKESKMLGLIGTGQATILGIQVVDTSVFGGIILGCIAGYVFNRT
                     SNKTFKGALQIYSGANFSFICMFFVSILIGVVSNFIWPLAQQGIASLANVIKDTGTFG
                     LFLYGFLERILVPTGLHHLIYTPFQFSDLGGVLKVGADTVSGAYAIVMTEMNLPVERF
                     SDSIYYMATGFTKMFGYIGIGAAFIYTAYKQNKKKVKATIIPLIITAVLASVTEPLDF
                     MFVFCAPFLFFVHAVIAGLFIALLKIFDVTALCGGNLLVSIIMNTTVGVEKTHWPVMM
                     ILGLAQIIVYFVVFSFLIKKFNYKTPGREDESTATGEEQSKQLNLDAGIENIIDGLGG
                     KENINTVENCITRLRVNVKDESKINEDIINLTPNSGIVRKGKDIQIIFGLHVHEVRRA
                     VEDFLEAY"
     gene            5142..6494
                     /locus_tag="PC494_000396"
     CDS             5142..6494
                     /locus_tag="PC494_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-alpha-glucosidase"
                     /protein_id="HDF3910926.1"
                     /translation="MIITIVGGGSTFTPGIVKSIALREKELELEEIRLFDIDKERQDK
                     VAVVVNWILKEDVKTDVKLTVTNCEKEAYTDATFIFAQMRVGKYEMREQDEKIPLKYG
                     CVGQETCGCGGMAYGLRTIQPMIKVIDDVEKYAKKDYWILNYSNPAAIVSEACRKLRP
                     NARIINICDMPIAIIDMIAGSLNINDVHNIRYDYFGLNHFGWFTSIDYKHRDLMEEIK
                     EYIKENKILLPKSYIENLNKSRSTGNRHAVSSWIHVWESVYTMLESFPKYLPNTYLTY
                     YLLSKETVEHSNINRTRANEVMESREKDLFEGVRHYLETGEISEKAFYAGSHGDWISD
                     LAVSIKNDTRSRFLVITENRGAIPNMPYDAMVEIPAYIGKDGPEVIARGPIPLFQQGL
                     MMQQLNSEKLIVEAYIENSYEKALQAFTLNKTIPSMNVAKEILDEMIEVNKEYWPELR
                     "
     gene            6625..7383
                     /locus_tag="PC494_000397"
     CDS             6625..7383
                     /locus_tag="PC494_000397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF3910927.1"
                     /translation="MNIINKIFWEEDRIGMITNNLEADTHSHCMLQLFLGIEDSIEIT
                     VNEKLVKCNCIIVDKNISHSFSARKKVYYSAIIEPTSIYAEQLTSKMNDFGYWICDND
                     GLEKLRQQGTFLIDNSSKEQYLRFMEMLNNYLNIPITLKHYDDRITELLNLLRTCNCD
                     NHTISSFADKVSLSASRLSHLFKEQIGIPLKSYILFHQMECAFRELLSGKNVTEASMT
                     AGFDTPSHFAGTVKRMMGMPVSLSLKDSEFLKVY"
     gene            7430..8149
                     /locus_tag="PC494_000398"
     CDS             7430..8149
                     /locus_tag="PC494_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglutaminase domain-containing protein"
                     /protein_id="HDF3910928.1"
                     /translation="MNKEYLEETKMLNYNEPQLKLLVSSKNWLELDDFHKIKSIYEFV
                     QNDILFGYNASDMLSATQVLNDGMGQCNTKATLLMALLRAVNIPCRLHAFDVTKDFQR
                     GATSKLISLLAPKYILHTWVEVFYQDRWIALEGVITDKKYLEAIQKKFFNHGGTFKKY
                     AIATNDLKNTSIDWDGKDTFIQKEAIVYDYGIFPSPDVFFSTHSQHMSKLKNFIYVHL
                     IRKIMTKNVCKARNNYIDKNE"
     gene            complement(8273..9673)
                     /locus_tag="PC494_000399"
     CDS             complement(8273..9673)
                     /locus_tag="PC494_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HDF3910929.1"
                     /translation="METQSNNKKGNLIIAIVMTGAFISSLSQTLLSTALPNIMSDFKI
                     TADIGQWLTTIYLLIAGIIVPTTAYLINRFSTRKLFITSMSIFSIGCIIALFSNNFST
                     MLIARVLQAMGSGSLMPLLQVIILYLCPEEKRGAAMSLVGITVGFAPAIGPTLSGWLV
                     DSFGWHSLFLFLSPIAILDVILSFILLRNVGETQKLKLDIPSIVLSSLGFGGLLIGFT
                     NQGNYGWTNIATYLPILIGIMSLILFTLRQLKSKEPFLELRVFKNKPFLISTILIMIV
                     YASMMSATLMIPLYVQSVRGFSALSSGSLMLPGAILMVVLNPIAGRHLDKYGPHALSI
                     LGTGCLFLGTLSFAFLGRDTSLIHVSLMYCIRMIGISMVLMPLTTWGIKTLDRELISH
                     ATAINNTLRQISGAIGSAILITIMTSATKKAHMSSNMLSNIHGIDVAFSIAATLAFTG
                     LIVSICFIKRHQIIRS"
     gene            complement(9677..10585)
                     /locus_tag="PC494_000400"
     CDS             complement(9677..10585)
                     /locus_tag="PC494_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDF3910930.1"
                     /translation="MKGDNKVTEKQRLIITIAQKIFDQKGFQNTSISDVVKECKMSKA
                     TFYKHFETKESFICEIINYYDEKFLEIIHSINENNDIPSSEKLNRKIIAVWKNIFSRT
                     TINTYIRENFSEEQRKATSKLQTKSRANLLNEYKLSLFDNYGDKIEKIIFDLVFLLDA
                     LIHQFIYIIHVQKREINVYFIAKFTIQILDLVVENMDNLNPLIEKSMFLHKQEDEVYF
                     SLHNKSLFFKTIQDIEELIKTDTSLLENPKLLEAIKKLYVEGKNQQYDSLIMDAMIAY
                     LEKEDTLRPKVLLLNSIKNQLKKETL"
     gene            10846..11493
                     /locus_tag="PC494_000401"
     CDS             10846..11493
                     /locus_tag="PC494_000401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HDF3910931.1"
                     /translation="MKKKICVAIIFALFIVFVEMFIDSSSEGSKIMTAELSKYRKGVN
                     VLSINNIIVANKKYSLPKDYSPQESSEARDAFYKMNKDAQKSGLNLKAFSTYRSYEYQ
                     DRLFKSYVKEHGEKEANRFSAKPGESEHQTGLAFDIGGDDQSCWANKKFNNTKEAKWL
                     YENAYKYGFILRYPEGKENITGYMYESWHYRYVGTEHSKNFAMNNLTLEEYLHIN"
     gene            11818..14457
                     /locus_tag="PC494_000402"
     CDS             11818..14457
                     /locus_tag="PC494_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HDF3910932.1"
                     /translation="MSYKSTYQEVIKNLDSSLSGLSKERAEELLEKNGANELKEADKV
                     PTYKLFLESFKDPLVIILLIAALVQIFLGETVESIIIFAVIIINSVLGVVQTKKAESS
                     LESLKNLSAPNAKVIRDNKKMTIPAKNLVVGDIVFLEAGDYIPADGRLIEAQSLKVVE
                     GMLTGESEPVLKHIEKISEDVSLGDQKNMVFSGAVVVYGRGSFVVTGTGMNTEMGKIA
                     GLLESAENKLTPLQQKIEDFSKKLGVGIVILALLIFIIQVARNYFMAGNGEMTQIILD
                     SFMFSVAVAVAAIPEALSSIVTIVLAVGTNSMAKKQAIIRKLPAVETLGSTSVICTDK
                     TGTLTQNKMTVVDYYMYGTNNDELDKEKVNYSYHAKLLTMVSTLCNDSHITSDGKEVG
                     DPTEVALINYSSKNDLDYDKLRSKYIRINEIPFDSDRKLMSTVNSIYGDYIMFTKGAP
                     DIVFSRCKYALKNGSKVDITDEIIEEYKHKNEEFSNRALRVLAFAIKDVPEEDFIPSI
                     DDEHDMTLVGIMAMIDPPREEVMDAVKEAKSAGIKTVMITGDHKTTAAAIAKEIGIME
                     EGDLALTGKELDALSEEQLYEKLENISVYARVSPENKIRIVKAWQHKNNITAMTGDGV
                     NDAPALKQADIGIGMGSGTDVAKDASAMVLVDDNFASIVNAVEVGRTVYSNIIKSITY
                     LFAGNLGAIVSIVFAVFAGWSNPFTALQLLFINLVNDSLPAIALGFEKSEKNIMNKPP
                     RHPDESILAGGTLKAVAIRGCIIGVVTIIAQYIGLQVSPELGVAMAFSTLILARIMQT
                     LPARSNNQTVIKLGFFSNKYVIGAVLVCLGLYSLTLIPVLRGIFSIPTTFGLYQLGIC
                     LGLALISSILMELNKLINRSEVK"
     gene            complement(14515..15618)
                     /locus_tag="PC494_000403"
     CDS             complement(14515..15618)
                     /locus_tag="PC494_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphate aminotransferase family
                     protein"
                     /protein_id="HDF3910933.1"
                     /translation="MKLKINKAIEMQLKKSYAIESGHSEDVFEIDCGEGINTVSYSNK
                     AVEAFNALKFDMIRGYPHSIALKDNIVDYWKDFIALDTDRICLADGSIHVIYLLNRLF
                     IEKGDKVLGYSPQFSEYETDIKMHGATYDYVLLKKEDNFKFNEKEFIEKINPEYKVIY
                     IDNPNNPTGQIIPLSSIENIVKEAAKYDIAVMVDEAYGEYMPKENSAVKLLNNYDNVI
                     ALKTFSKGFGLAGLRAGYAVLPEQLVSPIKKISTPYEVSEISRSIAANLLDDVQFIEE
                     LKEKTKDIKNQLLIPWKNLNIAETSDTVSIMTVEHKNKDIDLQQEFAKLKIRVISGSD
                     FTGLDKNFIRFRMPEEKELPEVIKAFQIIDNIE"
     gene            15979..16800
                     /locus_tag="PC494_000404"
     CDS             15979..16800
                     /locus_tag="PC494_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HDF3910934.1"
                     /translation="MGYKLIVTDMDGTLLGNNHKVTDENKTALQKVIKSGINVTLATG
                     RAFDSAKCNVDFLKEDMPIIACNGSLIREQNGNIIYSNKIDTRTCLNILDVLDKYDIY
                     YQCNSIDSMLSKKIEGREDRLSVFLGSETEVIVKDDLREEIFKKDILKFVIIEEKNPS
                     ILDEIRKELRKVQGIKITSSWPNNIEVMNEGVDKGNAVKILAEKMNIDREDIIAFGDN
                     YNDIEMIKFAGLGVAMGNAEELIKQEADYVTDTNQDSGVAKAIYKFLELKESLSS"
     misc_binding    16879..17090
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            17177..18493
                     /gene="argH"
                     /locus_tag="PC494_000405"
     CDS             17177..18493
                     /gene="argH"
                     /locus_tag="PC494_000405"
                     /EC_number="4.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012101354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
                     /protein_id="HDF3910935.1"
                     /translation="MKLWGGRFRKAENQLMEEFNKSFGYDCVLYKKDIEGSVAHVHMQ
                     VKCGLLTEEEGKSITEGLKGILEDVENGKLVLDGEYEDIHSFTEINLIQRIGDVGKKL
                     HTARSRNDQVAVDMRLYAKEKANDLVGLISEFKATIKDVADKNPVMMPGYTHLQRAQV
                     VTFKHHLMAYYSMFDRDEKRIKNAIEILDESPLGCGALAGTTHDIDRSITCEQLGFKK
                     VVDNFMDGVSDRDYLLELMSDFSIIMMHLSRLSEELILWSSQEFGFVEIDDLYTTGSS
                     IMPQKKNPDGAELIRGKTGRVYGNLFGLFTVMKGIPLAYNKDMQEDKEGFFDSVHTLE
                     MCIQIMDRMIATLKVNEDKMKQAVKNGFLNATEVADYLVKNNVAFRDAHGIVGSIVIY
                     CEDNKKAIEDLTLEELQKFSDAFKEDIYDFIDYESILNKGIKKNLK"
     gene            18742..19080
                     /locus_tag="PC494_000406"
     CDS             18742..19080
                     /locus_tag="PC494_000406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2325 domain-containing protein"
                     /protein_id="HDF3910936.1"
                     /translation="MNLLVIGGHERMEKDYMVMAKKKGYKTKVYTTMSSKLNNSIGRP
                     DAVVILTSTVSHKMSRTVESQAKKQDILIVRHKNSSKVAFNECLDMVDECLGNCSKCK
                     LKDKQKQKNI"
     gene            complement(19207..20496)
                     /locus_tag="PC494_000407"
     CDS             complement(19207..20496)
                     /locus_tag="PC494_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HDF3910937.1"
                     /translation="MKRNLSLLLICLLIFTSFLGSSNISFADNEPAIVAKHAVLMDYE
                     SGKILYNKDGNSKLYPASTTKVWTACLVLKEVKDLNQVIEIKDLPQIDGSSMYLKNGE
                     SFTVKQLLDALLVHSANDAAFVLARYVGGGNVQKFIDLMNSEAKKIGATNTHFNNPHG
                     LPDPNHYTTAHDMALIAREAMNNDTFRQIVKTKSLKFEATKAYPYERYFVNTNKFLTS
                     HDKITYKGQPINIKYDIVDGIKTGYTDAAGKCLLSSAVKDGRRVIVAVFNSTNADLYL
                     DSRILIDYGFDNFKCATIVDKEKYTDTKKVLFTKQHELIYEPKNSYRIFLEKDESQGN
                     YDTKTELNKIDLPIKKGAKVGTLNVYNNGKLENSIDLIAKNNLDSSLPFLTENNVLMT
                     FVKIIAGILVLLVLFIIASNIKKKKRKKARSKKNMKK"
     gene            20576..21280
                     /locus_tag="PC494_000408"
     CDS             20576..21280
                     /locus_tag="PC494_000408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="HDF3910938.1"
                     /translation="MKKKVKFISFFVLFILIISSIIVYKSLIFKDDIYVVSKKNLPNE
                     KTHVVENEIKGEDNNHSKVTKDIDKNFQNNKITIYISGAVNRPGIVTIESDKRLYDAV
                     ELLGGTTKEADLNGVNLSVRLEDEQHYIIPKIGEATSVTSNDDSNKPNQKNESRGEPK
                     NKSNKNISNESKVNINVATIEELDSLPGVGEATANKILQHREENGQFSSIEEIKNVNG
                     IGDKKYENIKDLICVD"
     gene            21372..22418
                     /gene="selD"
                     /locus_tag="PC494_000409"
     CDS             21372..22418
                     /gene="selD"
                     /locus_tag="PC494_000409"
                     /EC_number="2.7.9.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015617929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_except=(pos:21420..21422,aa:Sec)
                     /transl_table=11
                     /product="selenide, water dikinase SelD"
                     /protein_id="HDF3910939.1"
                     /translation="MKKEQKKLTEMTTAGGUAAKIGPEVLASVLSQLPKNDNIENLLV
                     GLDTADDAAVYKLNDDMALIQTLDFFTPMVDDPYVFGQIAASNSLSDVYAMGGKPLVA
                     MNIVCFPSCHDMDVLAEILKGGFDKVKESGALLVGGHTVDDKEPKYGLSVSGIVSPNK
                     VLSNATAKPGDKLIITKPIGVGVLNTAMKEGMVEQHIADKVIEIMIHLNKYAAMSFEK
                     FDVNSVTDITGFGLLGHTLEMAKASEVSIEIESKHVPIIEGAIEMAQMGIIPAGMYKN
                     MHYVSKDVEVVGNIEVAVQDILYDPQTSGGLLISVKEELAEELVKDMKLNGAIEAKII
                     GSVVPKGEKYITVL"
     gene            22436..23848
                     /locus_tag="PC494_000410"
     CDS             22436..23848
                     /locus_tag="PC494_000410"
                     /EC_number="2.9.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-seryl-tRNA(Sec) selenium transferase"
                     /protein_id="HDF3910940.1"
                     /translation="MIVLSKRELFAMLPSVDEVLSDNRIVEIINEYPRSLVLESVREV
                     IDLKRQFILRLKEDASNSVTIEFGEIIESAIERVKLNYSLSLKKVINATGTVIHTNLG
                     RSLLSEDIKDELWCAASRYSNLEYDLDNGERGSRYSHLTSTIKRLTGAEDVLVVNNNA
                     AAVLLVLSTMAKGGEAIVSRGELVEVGGSFRIPSIMALSGAELVEVGSTNKTHLKDYK
                     EAITEDTNVLMKVHTSNYRIMGFTESVSIEELVNLGKKYKLPVIEDLGSGVFIDLSKY
                     GLSYEPTVLDSIRQGADVVTFSGDKMLGGPQAGIIVGKKEYIEKMKKNQLTRALRVDK
                     LTICALEATLRMYLDETKAIENIPTLKMLTYKIEELEVKANKLFEKITALNLNANINI
                     EDGFSQVGGGSMPLETISTKVISITPEHMNVSSLEKKLRLSEAHIIARVYDNKYVLDV
                     RTIFDDEFDVIVEELRKAFN"
     gene            23962..25845
                     /gene="selB"
                     /locus_tag="PC494_000411"
     CDS             23962..25845
                     /gene="selB"
                     /locus_tag="PC494_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="selenocysteine-specific translation elongation
                     factor"
                     /protein_id="HDF3910941.1"
                     /translation="MKNVVIGTAGHIDHGKTTLIKALTGRETDTLDEEKKRGISINLG
                     FTYFDLPNNRRAGIVDVPGHEKFIKNMLAGASGIDIVLLVVAADEGVMPQTVEHLDIL
                     SFLNIKNGIVVLTKSDTVDDEFRELVKEDICEKIKGTFLEDAEIIEVDSISKRGIDTL
                     IEKIDKMSDDIEDKNENSPARLNIDRVFSIKGFGTVITGTLIEGKISIEDDLVIYPQV
                     LKTKIRSIQVHGENKDTAYAGQRTAINISNVKVDDIKRGDVLAAPNSLEESMMLDVKL
                     SLVNHLDKGLKHWDRLRLYHGTREILCRAVPLDKELIESGESGYVQLRLEESIVSKKG
                     DTFVVRRYSPMETIGGGVIIDPSPKKHKKFDEKVIEALKIKEKGELKDIIEEYLKRNL
                     KNYPNIKEIMSYSGAHEEDVKRALETLISEDKVFIIGNMYMHINQYNKLKENTIKLLS
                     EYHKKYRLRKGILKEEVRSKIESNFKTREMDILLEKLSTENAIKIENNIVSLLDFEVI
                     LNDKQKEIAKKIEKRLKSCGVSSILTIDEVSEGNHNYAEVLESMIGNKVEKLDDLYIM
                     DKDIYENAKNILINYIKENKEITLGEYRDLIDSSRKNCMIILENFDRNKITKRVENKR
                     ILF"
     gene            25950..28688
                     /locus_tag="PC494_000412"
     CDS             25950..28688
                     /locus_tag="PC494_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation-associated two-component system
                     sensor histidine kinase"
                     /protein_id="HDF3910942.1"
                     /translation="MKNIIPDVKPDIKEREDMSLLFIIMGSVLLLFIIKDIEKYETLL
                     HAIYTIFLVATGVIIFNTTKFKVDSFSTFLGLIFIATGVLECIYLFNSLGIKTKSIME
                     INITISAITDLFPILGVYLSFKFVKDNKQIYSSVILFIATATLTITSLFIISGICDYL
                     GNGKSQYALGVIISIFIIIISIVSGIELNSSSNKGKWEYDEKKIFNRIIVIIILSRVP
                     NLLHIVIDNRNVERILSQIIINVALYYLYNYIVSKNIKKTALELHDTNEELTKKTESL
                     KEKNKKLIYETEKIEELKGILMKRESRLQSTLDVAVNSIVVFSKDGEITYANKSFRNT
                     FGDYKEQDKLTDKIKNFNDLIESIHYVFVHEKNAEKLISTSDNKVYQAIFAPLIIASQ
                     TEGVLCVLEDKTKKKEYERKLIEANKRSKDFLESIGDGIVVLEGNNKIYVNNACREIF
                     KNNLESIDFSLVCKSEESIEKRYVIDGEVKYVEMSFSQYTNAGTNKTIIVIRDTTSRK
                     ISQIKLEESQSSYSRFIDILPDGICLLKEDLSINYANKSFLDMLAFTNIDDIKDSNIK
                     LLMNANTEEKMKFTDNMAKVLNENRSILLLEYELINSYDDIVEVELSALPFAIYNTRY
                     IMLIIKDLVHKKYSEQAEKELLERFKTDKIKTEFFANMSHELKTPLNVISSSNQLVDS
                     FYRNEKIKDYNNNIKSHVDLVRQSSYRLQRLINNIIDLTKMESGFYTLKLAKYNIVSV
                     IEDLFMNIEEYALRKDIKILFDTDLEEINVYIDKVEIERIMLNLLSNCIKFTDNGGWI
                     YVSIHYKIDKVIISVKDTGVGIPQDKLELIFEEFSQVDKTLSRNTEGSGIGLAIVKNL
                     VSLHGGDIEVVSEVNKGTEFLISLPMKGFSSEHYTEDKRIYNIQEKIKIEFSDIYY"
     gene            complement(28807..29751)
                     /gene="manA"
                     /locus_tag="PC494_000413"
     CDS             complement(28807..29751)
                     /gene="manA"
                     /locus_tag="PC494_000413"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HDF3910943.1"
                     /translation="MEPLFLKPIFMDRIWGGTALKDKFNYEIDSPTTGECWAISSHKN
                     GDCLIENGKYKGKKLSELWNKNRELFGNTPGDKFPLLTKILDANDNLSVQVHPNDEYA
                     KKNENGELGKTECWYVIDCSDDAEIIIGHNAKSHKEFVNMVNNNEWDKLLRKVNIKKG
                     DFFYVPSGTIHAICKGTLILETQQNSDTTYRVYDYDRTDNSGNKRELHVQKSIDVTNV
                     PHINFDTDYKIVSTSDFKCTTFVSNEFFSVYKLDVFGKCNFTHNTPFSLYSVLDGNGK
                     LIHNSVEYNLKKGMHFILPNDFGDFSFEGNLEIICSHI"
     gene            29924..31285
                     /locus_tag="PC494_000414"
     CDS             29924..31285
                     /locus_tag="PC494_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HDF3910944.1"
                     /translation="MELFKAESKKYKKEFLKLLEQWVSIPSFYDRKTVSKDMPFGKGV
                     YDALNWFENLGRENNFKVKNIDNHAVQIEYGNGKEYVDIFGHCDVVNPGEGWDSEPFK
                     LNIIGDKLVARGVSDNKGPMIVNFLALKMIKDLDINLKRKVRLIAGGNEESGFKCIKH
                     YYSKEPYGVCGFTPDAKFPVLNGEKGGAIIKLISNIDDKSLYISGGIEFNTIPDKVYI
                     KNVEKLGKDNICFDINNISINYDNGNYIVYGKGGHSSKPEKSINPILATIKLLSENID
                     EKWTKDLYKLINQDNINGNLFGLNIEGKCGILSMVPTIINIVDGKLEVVLSVRYPEIL
                     TIEDIIKKFNLYMEQNNINKFELIGENLKQANYIDRNSKLVRSLHDIYIKYSGDLKND
                     VRVTSAGSYASEMNNSVIFGCEFPDGSFGNVHSANEFASLDRFITAIGIYAEAIITLC
                     NKI"
     gene            31373..33262
                     /locus_tag="PC494_000415"
     CDS             31373..33262
                     /locus_tag="PC494_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HDF3910945.1"
                     /translation="MITKKHAIIVKSLSNKDGYMTSNELAIKLDVSTKTIKRYIADLN
                     SVLSKYDLVIASSRGIGYKLSGSKNNIARAVKEANKYIDGFLDDSEESRMSNIICMLI
                     NRNYMSIEAMAEELNLSIAAINKLSSKLKRKLEKYDLVIKSKPYYGSYIHGEEINIRQ
                     LITDYAIKLDEKSKVKVFLDDISENDIHCIESILEKHLREKDTIISDKDFNLLLSKII
                     VSVFRSKRGHSNNINLMDTSYRFHNYYFIENLMKEISDKIGFKLIEDEVIYISNYSGV
                     IAYKGTQGRKNTSEIEERISTVISSALQDIFLISGSDYTKDDEFMVAISDHIKRFLNR
                     ARANVKSNNPLLHQIKEKFPIAFNLAVFLSNKLETEFNLKLDEDELGYIAIHFAASNE
                     RMKKNTSKKICIVCHYGIGTGQLISEKLKQNISDLSVVGVYPVRYLDMAISQDVDLIV
                     STVELKGYEKPVLYIENIFDDSLIENVNKAFYEKEERRKIISNMFDEKAFFSIKANTK
                     EEVIISLSNKLKERDFIEESSIKSIIDRENISSTEIGNLVAIPHTIVKGDKKSIIGVG
                     ILENPIIWDKQEVQLVFMVFFNTKEKHNFSIFKYLYNFIKDEGGVRGIIKICDFNKLM
                     ALIGN"
     gene            33277..33732
                     /locus_tag="PC494_000416"
     CDS             33277..33732
                     /locus_tag="PC494_000416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDF3910946.1"
                     /translation="MGTNIFNKEYVFLNVDAKSKVEVLKFISKKAKDLNLAEDESLVY
                     EGLMAREEQFTTNLGESIAIPHTKNDAIENPAVVVLKFNEDVVWNEGEDKVKLAISLL
                     MPGKSKENIHLKLLSSLSRKLINKEFKDSLLKSDNVEEISNLINEALGL"
     gene            33791..34108
                     /locus_tag="PC494_000417"
     CDS             33791..34108
                     /locus_tag="PC494_000417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HDF3910947.1"
                     /translation="MNKKLVALCACPMGLAHTFMAAEAIEQAAKALGYEAKVETQGAD
                     GVQNELTRDDILGATMIIHAVAITPEGMERFDGCEVYEVELQEAIKNAEGVIKEIEED
                     LGI"
     gene            34133..35395
                     /locus_tag="PC494_000418"
     CDS             34133..35395
                     /locus_tag="PC494_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HDF3910948.1"
                     /translation="MAIKKKVINSSGASTTGGNNVGKSTPSSPTQSKGNGKWKEISKH
                     IMTGISYMIPVLVMGGLIGALSQLIPYAILGLDPSVGIVDAMNSGEFTGFKLSLLNIA
                     QLMSNFGFTLFGFAIPLFAAFCANSIGGKTALIAGFIGGYIANKPVGVPQFVDGQWTE
                     VVPVASGFLGAILIAFIIGYFVKWLNKSIKVSHNWLAFKTTFLIPLIASLACMVLMIF
                     IITPFGGLINESMKNFLTAAGAAGEYVYATALAAATAFDLGGPINKAAGFVALGLTTE
                     NVLPITARTIAIVVPPIGLGLTTLLDKRLVGRRVYDRQFYQAGKTSIFLSFMGISEGA
                     IPFALERPGFVIPLNIVGSVIGAITGIILGAIQWFPESAIWAWPLVDNLFGYIIGIAV
                     GAIFIAVGNIFYRNKLIKDGKLVVDYID"
     gene            35500..36564
                     /locus_tag="PC494_000419"
     CDS             35500..36564
                     /locus_tag="PC494_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HDF3910949.1"
                     /translation="MDKIEKVREYFREYDIDGFLINSPTNKFYVGNLFSSSGYVFITK
                     ESQYIIVDFRYFEEIKRKSSLFNVVLMDKTRTHFDIINDICREQNIKEIGFEGNEVSF
                     DLYRSMSNKLSATLKSVDLSTLRETKNEDEIKYIKKACEIVDATFYHIVDFIKVGMTE
                     KQVENEIVRIIKDLGGQKESFDTIVASGLRGALPHGKASEKVIEYGDFVTFDFGAKYN
                     NYCSDITRTICMGTINKELEEIYNIVRKANEECIRVLRPGMTTGEIDKVARDIIGSYG
                     YANNFGHNLGHGVGIMVHEYPALAPESNEVLKEGMIVTIEPGIYVPSLGGVRIEDDVL
                     ITQDGCMRLTTSTKDLIVVS"
     gene            36618..37796
                     /locus_tag="PC494_000420"
     CDS             36618..37796
                     /locus_tag="PC494_000420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PatB family C-S lyase"
                     /protein_id="HDF3910950.1"
                     /translation="MYNFDDKPDRVSEKCRKWDLNIIRDKFGDIREDFIPMWIADMDF
                     KIPTEIENKFIEAVRRGVFGYTYCYDEFYDSVIGWQKNMHEVNVEKEWITLTYGTVST
                     LHYVVQAFCKKGDSIILNTPVYDPFESSAKKQGVNVICNTLDVVNDRYYINFDKLEVQ
                     IKENKPKLMMFCTPHNPSGRIWTIEEMTRVATICKENNVILVADEVHAEHIHYGTFNS
                     ILKIGKELLENVILLTSPNKGFNLGGLKTSYSIVINKDIRDKFRNKLKQNSITSPNVF
                     GIIGLITAYNECHEWLSGVNEYIKSNYELLETWVNKYNKIKLMKMESSYLAWMDISGL
                     GISASEFTDKLAIDTGVLLEDGSHFVKDGEKYVRINLGTQKENVIEALNRMDLFLKSL
                     "
     gene            complement(37987..39045)
                     /locus_tag="PC494_000421"
     CDS             complement(37987..39045)
                     /locus_tag="PC494_000421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HDF3910951.1"
                     /translation="MNKKKITFIFVILILALILFSFFRSSSQNTKYSKTSYYLGTVNE
                     VTVFNVKESKSDKILNECDSILRYIDNKMSTHIPGSDVSKINDNAGKKFVRVSDDTFF
                     VVKEAIQYSKLSDGYFDITIGPLSNLWAIGTDKAKVPSDSKIQKLLPLIDYKNIILDE
                     KNKSIKLTKENMKIDLGAIAKGYAADKIVAYLKSEDVKKGLVNLGGNIFTLENGKNDK
                     PFKIGIQDPTSKNGESIGNIETTNKSVVTSGIYERFIEKDGKIYHHMLNPFTGYPFEN
                     NLSSVTIISDKSINCDALSTSTFGLGLEKGMNLINKIDNVDAIFITKDKKVYLTKGIK
                     DNFKLTDKSFSIEKLNKQ"
     gene            39112..39483
                     /locus_tag="PC494_000422"
     CDS             39112..39483
                     /locus_tag="PC494_000422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NusG domain II-containing protein"
                     /protein_id="HDF3910952.1"
                     /translation="MKKKDILLILGILVVITACYGIINVINSKNAGNIEIYVDNKLYK
                     TVSINAKEEFKIESRGGYNIVKIHDKGVEIVDASCPDKVCVHTGFINKPSQSIVCIPN
                     RVSIKINTNEKNDNQEDIISK"
     gene            39520..40194
                     /locus_tag="PC494_000423"
     CDS             39520..40194
                     /locus_tag="PC494_000423"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HDF3910953.1"
                     /translation="MVNLGNDWDELLKEEFEKDYYLNLRKFLIEEYKTRQIFPNMHNI
                     YEALKHTSYKDTKVLILGQDPYHGDNQAHGLAFSVQPQVKTPPSLLNMYKELKDDLGC
                     FIPNNGYLMPWADQGVLLLNTALTVRAHEANSHKNKGWEIFTDRVISILSEREDPVIF
                     VLWGSNARKKVELIDTSKHYILEAPHPSPLSASKGFFGCKHFSKINEILKKLGKEPIN
                     WQIENI"
     gene            40443..41282
                     /locus_tag="PC494_000424"
     CDS             40443..41282
                     /locus_tag="PC494_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HDF3910954.1"
                     /translation="MNFKKLSNAKVSVMAVVLSVGILSGYSALNKQVTLVVRGEERTI
                     STFSSNVGDLLESQNISYDSNDIVTLDENTKLSNGDKIEVIDVKEKTVVETKDIPFEV
                     TVVEDGSLLKGDSKVKEEGKSGKSELIYKETYHNGKKVEKEFVKKVVKAEPVNKVVSK
                     GTKVEMQVASSRGESSRRMASSSSSSSSSNNGKNMRVVATAYTGHSITATGTKPKWGT
                     IAVDPKVIPYGTKVYIPQFDMVFTAEDCGGAIKGNKIDIYMNDSKTVYNWGRKTIDIR
                     ILK"
     gene            41526..41622
                     /locus_tag="PC494_000425"
     tRNA            41526..41622
                     /locus_tag="PC494_000425"
                     /product="tRNA-Sec"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:41560..41562,aa:Sec,seq:tca)
     gene            41773..42480
                     /locus_tag="PC494_000426"
     CDS             41773..42480
                     /locus_tag="PC494_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA threonylcarbamoyladenosine dehydratase"
                     /protein_id="HDF3910955.1"
                     /translation="MENNFTTRTSFLVGDDGIKKLNNSNIIVFGVGGVGSFTVEALAR
                     AGVGNITIVDFDDVDITNINRQIPALHSTVGRYKVDVMEERILDINPNINIKKIRSLY
                     NKDTSDEILTERYDYVVDAIDMVSSKIHLIETCEKKGLKIISSMGMGNKLDPTKIVVT
                     DIHKTSTCPLAKVMRKELRDRGIKKLKVVYSTEQPIELKKKVMNGRKVTPGSVSFVPS
                     VGGLIIASVIVNELLGQ"
     gene            complement(42622..43458)
                     /locus_tag="PC494_000427"
     CDS             complement(42622..43458)
                     /locus_tag="PC494_000427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HDF3910956.1"
                     /translation="MRNKIFLSILIIISLLIGCDKKSLLSIHMIDVGQGDSILVQTPT
                     NKNILIDGGDEDSENIIISYLRQKRIKTIDIIIATHPDSDHIGSLDNIIKKFNVNSIY
                     MPEQSTDSKAYQNLINSCTDKNLSIQHLYKNDVLNIDNNINIYVLSPSYIQEESNLNS
                     IVFKLTFNDNSFLFMGDAEEENEKEILHSFKLNNINFIKIGHHGSNSSSSLEFIKKIS
                     PDIAAISCGYKNQYGHPHREVINNLKQNHVSIYRTDRIGDIVFYSDGEIIFTKYNYEI
                     DT"
     gene            43646..44551
                     /locus_tag="PC494_000428"
     CDS             43646..44551
                     /locus_tag="PC494_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2156 domain-containing protein"
                     /protein_id="HDF3910957.1"
                     /translation="MFFKDIELNSKKELDPYFDLVDYEACEYCFSTLYMWQHVYKTGY
                     YIGEDFAVLVGEYEGDSFSILPLAKKDKLPEVVDFVLEYFSKNNKKIYLRGITTEVVE
                     FLKEKYPGRFEYIEERDLFDYIYDAESLRTLAGKKNQKKRNHINYFLKEYAGRYEAKL
                     LDKENFDECLVLMKEWESNKEENNEFDESMDDELIGIKKIFNHYDILKDKVKVFGVYV
                     DGKLEAFSIGELLNPNMALIHIEKANPDIRGLYPFINQQFLVSEFKDVEFVNREEDLG
                     IEGLRKAKLSYHPCRFVEKYSVREA"
     gene            44560..45744
                     /locus_tag="PC494_000429"
     CDS             44560..45744
                     /locus_tag="PC494_000429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDF3910958.1"
                     /translation="MEIRYAKEEEIESIKDIWSYCFNDTESFMKYYFNDKYKSENTVV
                     ALDEGKIISSLQLNQYKLLLNSKVYNTSYVVGVSTLPEGRGAGYMNKVMKFTLNELYK
                     KGQLVSILMPIDYRLYRRFGYEHCYDQIEYTINTDDLKNFKSSGKMIKSNLSQIDDLI
                     QIDRTFLNEVNGNVLKDEHYYENLFKEIQSEDGFLYIHEGNEKDGYIVYFLQEDKMFV
                     RELFYKNIDALKSMLKFIYNHNTQCKIVTISTPTIDKIRFILDNPKDSDIKIKPFMMG
                     RVINVKKFIEDIDIEKDINSSFNLLIEDKFIDENNGLFKISIQNKKVSVEQLDKKGAE
                     KPQEDFDIKLDINTLTQLSFSYIDVNEAIFLNDIKDVSEETLETLNCIFSKKNNYINE
                     YI"
     gene            45859..47160
                     /locus_tag="PC494_000430"
     CDS             45859..47160
                     /locus_tag="PC494_000430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComEC/Rec2 family competence protein"
                     /protein_id="HDF3910959.1"
                     /translation="MGVIIIQIRRPLLIILMFVVAISFIITNNTKNDEELNDKIITIQ
                     GVVKGKIEKKRYNQYKVGVFLINDYTKNKNLKIGQKVNITGKFKSLDKMKYDDFDYGR
                     YIKSTGYKGIVYINNYKIIDKNKLYSLIGEIKFYISKTYRYLYKKNSDFINSILLAEV
                     ENLTEEQKEIFTRTGTSHVISISGLHTGILCVIISFLLRGINKLYKLLILSIFITLYC
                     IMVGASPSIIRSIAFVMIFYLSIFIDRKKDGISALSLIGIILIMNNPYVIYNVSFQLS
                     FLATLSILIFYNKINSIIKLSMVSLTISSNILTLPIIYYTFKGIPLLSIIGNLIIVPF
                     VGVIMYLSIASLIVFKVSVVIAKIISFFNSTFIESIFFLLEKISNLSFAYINIENPKF
                     YIVVIYYIGVFFYIFYIEGKEIKEQENELQGYYKECKREKL"
     gene            47114..48157
                     /gene="holA"
                     /locus_tag="PC494_000431"
     CDS             47114..48157
                     /gene="holA"
                     /locus_tag="PC494_000431"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HDF3910960.1"
                     /translation="MNYKDIIRNVKEKNFEKMYLFYGREYYLIENAIKAFKDSLNEGM
                     LDFNLDIIDGKEIVLNQLISSIETLPFMDDRKIVIIKDFELLKGKKKNFTDSDEKYLI
                     EHLDNIPDTTTIVFVVYGDVDKRKSLVKKIGNNGIVFDCDKLSDMDLFKWIKKSFALN
                     DVIIDNSQIMYFIEQEGYRDKSSEKTLSDLENEINKISSFVGKGNNVTNDVIDKLSQK
                     KVENDIFKLIDYIGEQNASNAMKILNDMIQEGESVLGIFSMIARQFKIIMQVRQLQLD
                     GYSTKLIADKLKMHQFVVGKALKQTKNFSDDIIVEILNYILESDYKIKTGLIRDTLAV
                     EMLVSRYCKREAI"
     gene            complement(48344..48610)
                     /gene="rpsT"
                     /locus_tag="PC494_000432"
     CDS             complement(48344..48610)
                     /gene="rpsT"
                     /locus_tag="PC494_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HDF3910961.1"
                     /translation="MANIKSAKKRISVIEKKTALNRVRKSQIKTAIRRFEDAVAAGNR
                     EDAVAKFQYAQKRIYQVASKGTIHKNAAARKVAKLAQKLNGMNA"
     gene            49206..49727
                     /locus_tag="PC494_000433"
     CDS             49206..49727
                     /locus_tag="PC494_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF3910962.1"
                     /translation="MDIAKLILNPARLRILQYIRLYGSVRTSDIVKYLNDIPRATVYH
                     HVKILEENNMIEVIKENRVRGTIEKVYALKEYTTSMEGETFVALSTAFYVGLMQEMNE
                     YFSRKEQDHKKDNVFFSSALLYMSDNEYENLLKSIADLLKPYIEQKPKSNLKLRKLSI
                     ISSPPVADNDKTK"
     gene            49761..50537
                     /locus_tag="PC494_000434"
     CDS             49761..50537
                     /locus_tag="PC494_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDF3910963.1"
                     /translation="MKFHEFGNKNRPHIMLIHGGGNAWWNYLRQAEVLSNKYHVILPT
                     LDGHGEEYETTYISTEDTADKLISYIDENCSGHLFALCGVSLGGQIVMELLSRKPNIT
                     KKAIIDGSICYPRPLMARFCIAGIRFFGGLLFSEKACRFQIAMMPKLLPENMQYPDEI
                     KAYYMTDMPHVRKETFYNMYRTYMMNYTLKENVKKTTAQVMYWYGEKEMKCVKKSAKL
                     FQSYVPSCEIYEAKSYNHGYLSLYLPNEWLEIAEPFFQKE"
     gene            50879..51832
                     /locus_tag="PC494_000435"
     CDS             50879..51832
                     /locus_tag="PC494_000435"
                     /EC_number="3.4.24.78"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GPR endopeptidase"
                     /protein_id="HDF3910964.1"
                     /translation="MISVRTDLALEASEMCEKSQEGSSIPGVKIETKELENCIVTKVE
                     VIDRQGAEIMNKDIGKYITLESNLMKFDDDESREEMISYLKEELVDIFGQDKNKKTLV
                     IGLGNRNITSDALGPKSVSKTLVTRHLFKNYNKDYDDDFTEVSALSPGVMGVTGIETS
                     EIVKSLVEKVKPDRVVAIDALASRKMERVNSTIQISTAGISPGGGVGNTRKSLTKETL
                     GVDVIAIGVPTVVDAATLTIDVLDMAIDNLIAQSEETESFYEMLKKLKEEEKYHLIKD
                     SLDPYDKNLIVTPKDIDDTIENLSIIISEGLNRSLHPGRLV"
     gene            51850..52869
                     /locus_tag="PC494_000436"
     CDS             51850..52869
                     /locus_tag="PC494_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage II sporulation protein P"
                     /protein_id="HDF3910965.1"
                     /translation="MFKKCIKVVTLTFILVCILPGKSLALNQDDFLKFLVNSSYPEAK
                     VEGNDTENKKNNKNKETSKENKEESKEGNTKSKDASKVDNKKESEKEYIKLYVGKENV
                     PDIESKNSDTTETNTTSSSDYKDDLRVTKENPRILIYHTHGCETYSNSPDGNYHSRDK
                     KNSVMEVGSALTSALDSKGWGVVHTTKYHDYPSYNNSYASSLKTIQSILPKYNSVDIA
                     IDLHRDARDLTNPATKEKDHLKYTTMINGERVSKFFFVVGGKNTNRKQLRALAEDITA
                     FAEKKYPGLVSPIVEKDYARFNQFAVKNHMLVEIGNNATSVEESKATTKYLAEILDEY
                     FKQKN"
     gene            52900..53151
                     /locus_tag="PC494_000437"
     CDS             52900..53151
                     /locus_tag="PC494_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3910966.1"
                     /translation="MSRLEKNIESKSKLRKYKYIMRILFLITMIICTSVCVFIVDSNA
                     KSMLGMKQYDFPSIKFDITKFDFDIPNFDIHEIIKKFNK"
     gene            53433..55238
                     /gene="lepA"
                     /locus_tag="PC494_000438"
     CDS             53433..55238
                     /gene="lepA"
                     /locus_tag="PC494_000438"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HDF3910967.1"
                     /translation="MDNKQSRTRNFSIIAHIDHGKSTLADRLIQQTGLVSERDMKSQL
                     LDNMDLERERGITIKLQNIRLMYKAKDGNEYYLNLIDTPGHVDFNYEVSRSLAACEGA
                     LLVVDAAQGVEAQTLANVYLAIDQDLEILPIINKIDLPSARPEEVKNEIEDLIGLDSS
                     EAPLISAKTGLNIEDVLEDIVKNVPPPKGDNEAPLKALIFDSYYDAYKGVVAYVRVFE
                     GTVKKGMTIKMMNTNKKFEVTEVGVMAPGQTELSELSAGDVGYIAASIKDIRSCRVGD
                     TITDSNNPTEEPLPGYKKATPMVYCGIYPGEGEKYENVRDALEKLQVNDAALEYEAET
                     SAALGFGFRCGFLGLLHMEIMQERLEREFNLDIITTAPSVIYRVTKMDGEVVMIQNPA
                     NLPEPSEIKMIEEPIVKGDIIVPKDYVGVVMELCQERRGNMLNMEYIDDRRVMLHYDL
                     PLNEVVYDFFDALKSRTRGYGSLDYEVKGYVASTLVKLDILINKEQVDALSFIVHETR
                     AFPRGKAMCEKLKGEIPRHQFAIPIQAAVGNKVIARETISALRKDVLAKCYGGDISRK
                     KKLLEKQKEGKKRMRQIGSVEVPQKAFMSVLKLDE"
     gene            55387..56724
                     /locus_tag="PC494_000439"
     CDS             55387..56724
                     /locus_tag="PC494_000439"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HDF3910968.1"
                     /translation="MINIEIPKKVDYIIKELEKNGYEAYIVGGCVRDCLLERVPNDWD
                     ITTSARPEVVVELFEKTIPTGIQHGTVTVMIEHEPFEVTTYRIDGNYSDGRHPDSIEF
                     TNNIVKDLSRRDFTINSIAYNSKTGLVDPFNGYEDIQNKYIRCVGNPVDRFEEDALRM
                     LRAVRFSAQLNFKIAEGTKQSIHKKADLIKNVSIERIQTEFNKILVSDSSKLNLLKST
                     GLLKFIIPEICELEDVTQHNPYHIYDVQKHTLIATEAIEDELYLKLTMLFHDLGKKVT
                     KTTDKNGVDHFYTHSRESVKIAKKILKRLKYDNYTINKVLILIQYHDYRIEPKRKIIK
                     KLLNKLEDVELFEDLIKVNWADTLAKNPKYAKQKILNLIECEKEFKHIINQKECFNLK
                     DLAINGKDLISIGIKPGKDIGHILNKMLEIVINNPELNEKEILKEKALNIYTF"
     gene            56957..58270
                     /locus_tag="PC494_000440"
     CDS             56957..58270
                     /locus_tag="PC494_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HDF3910969.1"
                     /translation="MHTQLQKTIGLSAALSTVVGMVIGSGVFFKPQAIYTTTNGAPGL
                     GIIAWLLGGFITITAGLTATEISAAIPKTGGMMIYIEEIYGEKLGFLTGWMQTVLFFP
                     GTSAALGVIFAQQASELLGMSPNNMANVLPIAVGVILFLALLNIIGSSLGGKVQTVAT
                     IGKMIPLILIIVFGFIKGQSSEVLNPFVGDGVNASNALGQVLIATLFAYDGWINVGAI
                     SGEMKSPEKDLPRAIVGGLSLVMAVYIIINIAYLWVVPASELATVTSPATLVATRLFG
                     NIGGKVITVGILISVFGTLNGYLLTGSRIPYTLAEMGTLPASKTLLKVNSGGSPVNSI
                     LLITVLACVYALSGQFNLLTDLTIFSIWVFYVLTFIGVMRLRRQKPDLHRPYKVPLYP
                     IIPIIAILGGLFVIINQILTSTVISLGGIFITLLGLPVYYYMKKR"
     gene            58442..59617
                     /locus_tag="PC494_000441"
     CDS             58442..59617
                     /locus_tag="PC494_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HDF3910970.1"
                     /translation="MLGLYVHIPFCVKKCKYCDFNSYKMDIDSKKRYIEDLKIEMELY
                     SNKLYKDNKYKNKECCSLNKNDKITSIFVGGGTPSILTSDEIREVFISIKEMFDIDEN
                     AEITIECNPGTLTLEKLKTMKEIGINRLSIGLQAIQEKHLNFIGRIHTYEEFEKNYKD
                     ALSVGFKNINIDLMYSLPNQTLCDWKETLEKVVHLNPTHISAYSLILEEGTELYNMYE
                     SNKFELIDENVDIEMYEYTINYLKSKGYNQYEISNYSKEGYNCEHNILYWECEHYIGI
                     GAGASGYINENRYNNVESLEDYHLSLVKREKPIQENEILSEKDMIEEKIFMGLRMNKG
                     IKFEDFKKKFGIDFREKYNKQIEMLLARKLINQSFEGIQLTQKGREISNSVFIEFME"
     gene            59720..60739
                     /gene="hrcA"
                     /locus_tag="PC494_000442"
     CDS             59720..60739
                     /gene="hrcA"
                     /locus_tag="PC494_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcription repressor HrcA"
                     /protein_id="HDF3910971.1"
                     /translation="MELNERKLNILKAIVKDYIETAEAIGSRTISKRHDLGVSAATIR
                     NEMADLEELGYLIQPHTSAGRVPSEKGYKLYVNSLMSKSELDDNDKILIEQCMNHNIN
                     HIKELIHETSKLLSQLTNYTTVAVTKSLINQSVIKHIQLVAMNDNNILLIVVTDKGDL
                     KKANLTTNVYLDQSKLNLISDNLTRKLLGKSITDLDDNLIAFIKYEISEYSGLIDELL
                     NALNSNMKEEDFSLSLNGATNIFSYPEFNDVLKAKSFLNMLEKKETIADIIKSKGIQK
                     DNLNIIIGSDNDCELAQDCSIVTATYNVDRDLVGRISFIGPTRMDYARIYSIINYMSL
                     LINRK"
     gene            60769..61389
                     /gene="grpE"
                     /locus_tag="PC494_000443"
     CDS             60769..61389
                     /gene="grpE"
                     /locus_tag="PC494_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HDF3910972.1"
                     /translation="MDKKNEQQEVREENDTSINQESETQVELEEEVVNEECETSSEKT
                     DEKEVDDENVTDINSKLAEKKLQDELDELNDKYQRLQAEYANYRRRTQQEKETIGVFA
                     NEKIITELIPVIDSMERALDACEDKEDTMYKGISLVHKQLIDTLVKFGVEEIEAESKE
                     FDPNLHLAVMQESVDGVEANQIVMVLQKGYKLGTKVVRPSMVKVSC"
     gene            61481..63328
                     /gene="dnaK"
                     /locus_tag="PC494_000444"
     CDS             61481..63328
                     /gene="dnaK"
                     /locus_tag="PC494_000444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000034699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HDF3910973.1"
                     /translation="MGKIIGIDLGTTNSCVAVLEGGEAQIIANSEGMRTTPSVVAFTK
                     DGERIVGEPAKRQAVTNADKTITSIKTHMGTDYKVNIDGKSYTPQEISAIILQKLKSD
                     AESYLGQTVTEAVITVPAYFTDAQRQATKDAGRIAGLDVKRIINEPTAAALAYGMDKL
                     DQEKKILVFDLGGGTFDVSILEIGDGTFEVLATAGNNRLGGDDFDQIVIDYLAEEFKK
                     AEGVDLRNDKMALQRLKEAAEKAKKELSSTMSSNINLPFITATAEGPKHLNIDLSRAK
                     FEELTRGLVEKTMEPTKTALQDAGLSTGDIDDVLLVGGSTRIPAVQEAVKKFIGKEPH
                     KGINPDECVAAGASIQAGVLAGDVKDLLLLDVTPLSLGIETMGNVMTKIIERNTTIPT
                     KKSQIFSTAADNQTAVDIHVLQGERSMAYDNTTLGRFQLTDIPPAQRGIPQIEVTFDI
                     DANGIVNVSAKDLGTGKEQKITITSNTNLSEAEIEQKIKEAEMNAEADKQKKEKIEAF
                     NQAESTIYQTEKTLNELGDKISSGEKEDIEKAIADLKAVKDNQDATAEELKKATDEVM
                     TKFQKVSQEMYQKAAQEQQAAQGAEQAQDNGPKDDNVVDADFKEVDEDK"
     gene            63539..64693
                     /gene="dnaJ"
                     /locus_tag="PC494_000445"
     CDS             63539..64693
                     /gene="dnaJ"
                     /locus_tag="PC494_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HDF3910974.1"
                     /translation="MSTKRDYYEVLGISKGAEAQEIKKAYRKLAMKYHPDRNPGDKEA
                     EEKFKEINEAYEVLSDDTKRKTYDQFGHDGLNGQGGFGGQGGFGGQGFGGFEDMFGDI
                     FGDMFGGSFGGGRARRRGPQRGADIRQSVTISFEEAAFGKKMSIKVNRSEECEECNGT
                     GAKPGTSKKTCSTCNGTGQVRTVQRTPFGNIASSRPCSACNGTGEVIESPCSKCHGTG
                     NTRKVKTIEVDIPAGIDDGQMIKLSGQGEVGEKGAPRGDLYIVVNVKSHPLFTRDGND
                     IYFEMPITFVQATLGDEIEVPTLDGKVKYSVPEGTQTGTVFRLKEKGIPRIRGNSRGD
                     QYVKVVVEIPKKLNDKQKELLREFAKECGSNVHEKKKTFGQKIEDMFKKK"
     gene            65659..66594
                     /locus_tag="PC494_000446"
     CDS             65659..66594
                     /locus_tag="PC494_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HDF3910975.1"
                     /translation="MYYIGVDIGGTGIQAGVVDNYGKIIFRSECKTVIEKGFEGILND
                     IKIMIYKLLEDNKLTMSDIKSIGFGVPGFINKEGLVTCVNLKWNKKAFNKELKRRFPD
                     VEIHGENDATVAALGEAKFGSMKGANVGVLYTLGTGVGGGIVINQKVFSGAHGLGSEI
                     GHQIIGENYFNCNCGNNGCVETFCSATAIIKYSQKLIEEGEKSRILDLAEGNLENVNA
                     KMVFDAYRENDLVAIKVINRFKEYLAKTFANTINSLDPEIISIGGGISKSSDIILDGI
                     EDLVRKFVLYKTEDIATITCATLGSDAGIIGAAFL"
     gene            66630..68003
                     /locus_tag="PC494_000447"
     CDS             66630..68003
                     /locus_tag="PC494_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDF3910976.1"
                     /translation="MGKTNARRTLFLIAIGSGTMLNPLNSSMISLALHSIQNDFHISF
                     TTVSWIVSAFYLASAIAQPVSGKIGDLIGRKVLFLSGLMLVILSASIVPLVQSFFILI
                     FIRVIQAIGTSTLYPSGVALIQNNIKERQSSALAVLTIFASTTAGLGPTLGGLLLDLG
                     GWHAIFLVNIPVVLVSICLGYFLFPKEVKEKKSIKETLKNVLSRLDIIGILLFSIAMI
                     FILLFLLSMKESFNLEQLIFGIILMCLFIWHELRTKLPFIDIKLFVSNPKLSKVYLQF
                     IILNFFNYILFFGLPSYFQDALHYSAKSTGLFMLFMSGIGIFISPLTGKWIDKSGTRF
                     PLVTSSIFMFISAVLLSVVFIHIPVIGKGIILSLAGISYGVGNVALQSSMFEESPRDS
                     IGTASGLFQTSRYLGSILATVLLGMVFEVNITSEQFQILGYVMVVLGTISFLLNFILK
                     KELRKVE"
     gene            complement(68191..68958)
                     /locus_tag="PC494_000448"
     CDS             complement(68191..68958)
                     /locus_tag="PC494_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF3910977.1"
                     /translation="MEELKDFLERQLNKKINIYPYENQKLDASSHLVTFNNAIYVIDF
                     LDKNNLDNLKGNFYLIYQSHIDFEYLKNIFYNLFEDINIIQHNGFFIVNSKYNLDINV
                     TTQNIIETETYQSTYIFYLGKLDSKADFDFRLQLCSDLLPHIIKDNAENKFLNLFDLI
                     RYKTLDLINEDNILNKLIDFNKIKSIDEELLYTGIKFINNDLNISKTSTSMFLHRNTL
                     VYRLEKINEILGFDLKNFENAMIFYLSVKSYFLYKKI"
     gene            complement(68988..70097)
                     /gene="ugpC"
                     /locus_tag="PC494_000449"
     CDS             complement(68988..70097)
                     /gene="ugpC"
                     /locus_tag="PC494_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003242648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     ATP-binding protein UgpC"
                     /protein_id="HDF3910978.1"
                     /translation="MSEVILKNISKLYSNGFNAVKNINIDIKDKEFIVLVGPSGCGKS
                     TTLRMIAGLEEISEGELYIGDKLVNDIEPKDRDIAMVFQNYALYPHLSVYENMAFALK
                     LRKLPKDEIDKKVKEAAKILDLLPLLNKKPKTLSGGQRQRVALGRAIVRNPKVFLMDE
                     PLSNLDAKLRTAMRTEITKLHQQLGTTFIYVTHDQVEAMTMADRIVVMKDGVVQQIAT
                     PQDVYDYPANIFVAGFIGAPQMNFIDVILIEENDEIYAQNEHIKLKLNKEKHYDLIKD
                     NYINNEVVIGIRPEDIHVEDTFIKSNPDTCFKSRIEIKELMGAETYAHLKLGENTITI
                     RFDSKNRINVGDDLTLSVDNSRVHIFDKETTLAIR"
     gene            70355..71092
                     /gene="cas6"
                     /locus_tag="PC494_000450"
     CDS             70355..71092
                     /gene="cas6"
                     /locus_tag="PC494_000450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated endoribonuclease Cas6"
                     /protein_id="HDF3910979.1"
                     /translation="MSRISIFMESCNGKFPNENSMLSVSFIKNILNAENKDFAKNIFN
                     YGKERKNNKQIKDINTAIYIPNLIRSKNELLVDGDIIFNISFYNYSMFSKLYNGILKV
                     KELEYKGYRFKIKNIKIHKEHEIKENGVIFKTMSPIIVKNKEGKYLDVEDSNYIECLN
                     YIANLTLESIRGSGLRKPLEFIPLNFKKRVLKEKIRGFKVREFYYINAYAGTFFLKGD
                     MEDLNALYKMGIGYRRTENAGMVDILK"
     gene            71097..72572
                     /locus_tag="PC494_000451"
     CDS             71097..72572
                     /locus_tag="PC494_000451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3910980.1"
                     /translation="MREIKAKFYRSGDIVRDIGIVYFYELLMDLKNELEKNDYKLKFT
                     CELNRNYLSLESAEYIDPKYISDYILENQLFKVFKNGKKETLEKIFSNIDNLTYVNFI
                     EELDKSSATAKQKEDIKKDFKNRRFPYVRNSGKYGLNTSLENMETNVKRIVDTVIKSN
                     IEIDEIDKLDLTQYEEKDSVCNVCNINKTTKLDIDLRERKDSKYNFLFRGAEKSGFKR
                     SGQVESNICFECEFFNLMCLLYINLKRPMVFAYTNDLRELAFLNHKIMLKRKMYSDKS
                     FYKKLLHEKISSIRLYRFDIVKNKGIILKFDSIIEYKELLKKIELIDIIDNYNFSREP
                     VNTKNLGKKMIDNGNLSNLKELLLDNISFLKQSTGTSREMDFVSSSYNIGLYIKLCWI
                     VDGGEEYKMKNYMESNLIYSRVGKDLFNKMTDESRRKNFSMKVIQLLKSNDRTQLFQT
                     IMHVLVSNGILIGEGFVEGLMQSSELELNTNVGLFIQEIMK"
     gene            72592..73605
                     /locus_tag="PC494_000452"
     CDS             72592..73605
                     /locus_tag="PC494_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DevR family CRISPR-associated autoregulator"
                     /protein_id="HDF3910981.1"
                     /translation="MNEKRVKGVTLTILTESPVPLSYDQGYGNYTPIKKEQYREKIHA
                     KTSIATITYDLRRMLHQEYGWNLSNIVFGKKGNIYPSIKKNVGCVDENGLETDVFGYL
                     IPLKDKGSISKASPLRIIPFRSLNPYIGSTQLITNRGFLSSEFGRKYYDEKEENEVPR
                     DENFPTTQALAIEETLSDYYVYTITLELDRIGVVEVEDGKLLLPEERKFMSKELREKA
                     VKDILDAITVFTRNIKHSSVLLKPLAVIGGAFDKVVPFFWDDVDYNADSGEINLEGVI
                     ETIESYSLKESNTILAINDRLKISNKKELNKFNLSKYPVKEIKNLADRLEIGEDNMWY
                     LKE"
     gene            73621..74418
                     /gene="cas5"
                     /locus_tag="PC494_000453"
     CDS             73621..74418
                     /gene="cas5"
                     /locus_tag="PC494_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated protein Cas5"
                     /protein_id="HDF3910982.1"
                     /translation="MKVLQCKLKQPTAHYRDPKVFQNEYISTLNLPSKTTIMGMITYL
                     CDRRLNSDIDIGIIGTHHHRELEFSRGENIDFWNEYTNMRKGKDKEKFLLQGNYYDYY
                     KEHKAQNSILNYEVLKEVELTIFISCKDDEELEFIKKKLESPCKYANLGRKEDFVIPS
                     EKGCFVKEVELKEVIPMNTRDAIKENIKLKNTYVRVDLRDKENVETIINQGVLIALPH
                     KYKDLEANRDDRVYEFCHYIYVDNDGIYPKNIKVNVCIDTKEVFTWL"
     gene            74445..76853
                     /locus_tag="PC494_000454"
     CDS             74445..76853
                     /locus_tag="PC494_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated helicase/endonuclease Cas3"
                     /protein_id="HDF3910983.1"
                     /translation="MKNIMQKEILAKSYNLRTNQQEQTLVEHIKDLFEVLESILELNL
                     YSDKDVEILKICCALHDLGKINSIMQQKMEINNKISYSCSEEERKKLESDKKSLKKIA
                     RHNIFSGAFLKDILEKMNLSEEDKLYIYKSIMLHHGNYEDYMRLSISKVQEEIYEYIE
                     KGILEKEEFNLKDIESYINNILNVDFKFGEDVLDYDYIDKLSESMFIDSDYNNGQIDD
                     SVLNYRKFKYILYKGMLNLIDHSASSRQKGIKFYNDFTDEEIDNMILNEIYKSQGNLE
                     KNNIEFNTIQKRLRELSGRNVLTVAFTGSGKTAADYRKTFKRKFFLVPNKISAESFYR
                     KNIFQNKNDLDTRSSNDYIGLLHGDINLYSENEDNGEHDFVLTLRDIDLSINFCKPCV
                     IATVDQLLLSMFKFPGYEKIFAAVKNASITVDEVHLLEPKMFLILIYFMQFACKYLDV
                     DFHLMTATLPKSYKEQMINKGIIFQEESNKNVTDKGEIVFIESNKEEEICEGKDVKVS
                     FIKEKEIKSIVEDALENKQKILIIKNTIDSVNRTYEFLKENLSDKYGGVDIDVLHSRF
                     KFKDKKEKYSKILNGEGDIWISTQSVEISLDLDFNIIISDLATMDSLIQRMGRCNRNN
                     KYEYGNFYILPSEDKIYDNKLKNTTKNILKDILKTNSIFTMGIRKTILDDYYDNSVVK
                     KYFEENFISCDKEIKNIYGINKEIFDGLDLIFNFEPYKNIVDSKKEAAKIFRDIDVSY
                     KIILEEDFYKEDRELQQDSIQVSGFIFNRLYYYGLISKVEGYMVLKSSSKFEYNSTVG
                     LILK"
     gene            77294..78241
                     /gene="prmA"
                     /locus_tag="PC494_000455"
     CDS             77294..78241
                     /gene="prmA"
                     /locus_tag="PC494_000455"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HDF3910984.1"
                     /translation="MNNWIEVTIKTTTEAVEPITNILYEQGAGGAVIEDPKDFLFQKK
                     NELDWDYVEEEVFKKNEEDDVLIKTYVSEEKNVMEFVEIIKQKVLGLKDFGIDIGEGS
                     VSLDQVNEADWANAWKAYYKPTKVGQRVVVKPTWEDYAMQEGDLIIELDPGMAFGTGT
                     HETTSMCIRELEKYVNKDSKVFDIGCGSGILAIAAAKLGAKEVVAVDLDEVAVKVAKE
                     NVLENKVEKSVSVMHGNLTDVIKDKADVIVANIIADIIKILAKDVQNFMKEDAIFISS
                     GIILDKVEEVKESLIENGFEIVEVQKLGEWSAIVSKLKK"
     gene            78260..79018
                     /locus_tag="PC494_000456"
     CDS             78260..79018
                     /locus_tag="PC494_000456"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HDF3910985.1"
                     /translation="MDRFFVEKNNINLQDKTCTIEGEDVKHISKVLRCKLGEKLEICD
                     KNNNEYICEIMNIDKSIVNLEILEKVDINRESELKVRLYQGLPKAPKMEMILQKLTEV
                     GVEEIILVQTKRSVVKVDDKKEDKKFERWERIIYEAAKQSKRGKIPKLRGVLSFKEAL
                     EDMKKNNVNICPYENERTVSIKHALKKCDSNIDSVGIFIGPEGGFSEEEIEQIQKNNC
                     NVVSLGPRILRTETASVVASTIALYELSDLGGEK"
     gene            79020..80318
                     /gene="mtaB"
                     /locus_tag="PC494_000457"
     CDS             79020..80318
                     /gene="mtaB"
                     /locus_tag="PC494_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-
                     methylthiotransferase MtaB"
                     /protein_id="HDF3910986.1"
                     /translation="MKKVAFYTLGCKVNQYETEAMLELFEKDGYEQVNSEEYADVYVI
                     NTCTVTHMSDRKSRQYIRRVKKKNPDAIIAVVGCYSQVSPEEILDIEEVNLVMGTNDR
                     RKIVEEIKKINSSKKVSTVDDIMKVKAFEEIEISQTNGKTRAFMKIQDGCDRFCTYCI
                     IPYARGRVRSRDIDSIVDEVKKLANNGYKEVVLTGIHVASYGKDLKDRDIKLLDVIKQ
                     INQIEKIERIRLSSVEPILFTDEFVNEVLKMDKVCPHYHLSLQSGCDETLKRMNRRYT
                     TLEYKTIVDRLRSKMPDVAITTDVIVGFPGETNEEFKKTYEFLKEIELSQMHIFKYSP
                     RKGTPAATMENQVDPQMKHFRSEQLLNLSKVNFNKFATKFIGRELDVLFEQNIEGNKY
                     EGLTSNYIRVVVESDKNIQGQILKVKINDVKDEYVEGILL"
     gene            80361..80711
                     /locus_tag="PC494_000458"
     CDS             80361..80711
                     /locus_tag="PC494_000458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine triad nucleotide-binding protein"
                     /protein_id="HDF3910987.1"
                     /translation="MDCIFCKIANGEIPSTKVYEDDRVLAFNDLNPVAPYHILVVPKK
                     HYDSLIDIPDKEMDIVSHIHVVINKIAKEKGFDQTGFRVINNCGSDGGQEVKHLHYHI
                     LAGKKLPNYEAGQN"
     gene            80874..81053
                     /locus_tag="PC494_000459"
     CDS             80874..81053
                     /locus_tag="PC494_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HDF3910988.1"
                     /translation="MSEVRVRENETLDSALRRFKRQCAMSGIMSEVRKREHYDKPSVK
                     RKKKAEAARRKNAKK"
     gene            81083..81526
                     /locus_tag="PC494_000460"
     CDS             81083..81526
                     /locus_tag="PC494_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GatB/YqeY domain-containing protein"
                     /protein_id="HDF3910989.1"
                     /translation="MSLKQKLQEDLKSSMKNKDTVRKSVVTLIRASIKQYEVDNRVEL
                     DEDGIIDVIAKQLKQRRDALVEFEKAGREDLIKETEGEIEVLKEYLPQQLSEEELEEI
                     VKSTISEVGATSMKDMGKIMSVIQPKVKGRADGKLINKLVKQNLQ"
     gene            81637..82134
                     /locus_tag="PC494_000461"
     CDS             81637..82134
                     /locus_tag="PC494_000461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan-rich sensory protein"
                     /protein_id="HDF3910990.1"
                     /translation="MIISVKEIRNFLINIFIPLIIGYLSSILTMIISGTDISTYYLQL
                     TKPSFAPPAFIFPIVWTILYILMGISSYLILRKGYNLPKVRDAIFYYGLQLVLNFIWS
                     ILFFGFGLRFTALIDIIIMILVSIIMISKFSKIDKRSGYINLIYLMWLVYAGFLNYFI
                     WFINK"
     gene            82327..82890
                     /gene="raiA"
                     /locus_tag="PC494_000462"
     CDS             82327..82890
                     /gene="raiA"
                     /locus_tag="PC494_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HDF3910991.1"
                     /translation="MQIIVSGRQMKLTDGIKGYVDGKLSRLEKYLDPESEVKVTVSAK
                     KDRQKVEVTIIPINGQIIRAEDVEDDLYAAIDIVCDKLSRQVVKYKTKVKDKVQNNKS
                     IRFENLDFIDNSSEFDDYDYDDEEDENIVIERRKKFNVKPMSSEEAILQMELVGHNFY
                     MFRNQDNFEINIVYKRKAGGYGLIEQD"
     gene            83103..83339
                     /locus_tag="PC494_000463"
     CDS             83103..83339
                     /locus_tag="PC494_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YabP/YqfC family sporulation protein"
                     /protein_id="HDF3910992.1"
                     /translation="MLEISTDLQVNQPVITVTSNTFISIENYLSILEYEVDLIRIKTK
                     VKTIKISGDKLSLKYITDSEIGIKGIIYNVEYVD"
     gene            83352..84695
                     /gene="yqfD"
                     /locus_tag="PC494_000464"
     CDS             83352..84695
                     /gene="yqfD"
                     /locus_tag="PC494_000464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation protein YqfD"
                     /protein_id="HDF3910993.1"
                     /translation="MISFIRGYYVIVVEGVGLEQFLNHLIRNGISVYNVTRIKNTKME
                     FHIDRQDIKDFKNVYRGSKFDIKVKQKTGVPFIIKRVYKHKGMWICALVSLFLLMSTS
                     QFVTDVYIQSPEGIKKEALRNELYKVGVRPGVYKKSIDRKEVRDHMMSKFNDVAYLSI
                     NVKGTNIFVTVTKKAESLKSTDQSNYCNVIALKNGIIEKVIPRSGKSVIKSGDIVQKG
                     DVLLNGANTKSIPEVWASTFYESTKKASYVDTVNKKTGEKKNIYTLSFYDKEFTMRKN
                     IKYKDYVVENKEKKLSIGNYTFPIKIKTSTFYETKKVEVKRNKEELKKELSEKALKEL
                     EYIIPASARIIDVKHNFKVNKNMLEYLITVQTSENIAKIYPLSKSEAERFIKEESKPD
                     EGEEEVPSNPEKRPLNDIRNEFDEDNKDNKDQNNSDENNSNQNSNNSQNNNSNNN"
     gene            84634..85749
                     /locus_tag="PC494_000465"
     CDS             84634..85749
                     /locus_tag="PC494_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HDF3910994.1"
                     /translation="MKIIVIKIVIIVKIIIAITTNKIKLKILGGLIQLIIQKKFTIAD
                     GNFERELFGNFDENVKLIEKTLNIDVILREGNIILIGEEKNVDSALKLMNELHQTVSN
                     GKHLDKQSISYSLSLLLEGSEQKIKELEGTIVITQRGKAVQPKTLGQKEYIKLIENND
                     ITFGVGPAGTGKTYLAVAMAVKAFKRDEVSRIILTRPAVEAGESLGFLPGDLKDKVDP
                     YLRPLYDALFEMLGADKFNKYLERGTIEVAPLAFMRGRTLDNSFIILDEAQNTTSEQM
                     KMFLTRLGFGSKAVVTGDVTQTDLPQNKKSGLIQATEILKGVPGIGSIMLTDRDVVRH
                     ELVQRIIRAYEKHDKREEFKKEERKKAKMQEKTFKRK"
     gene            85806..86267
                     /gene="ybeY"
                     /locus_tag="PC494_000466"
     CDS             85806..86267
                     /gene="ybeY"
                     /locus_tag="PC494_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HDF3910995.1"
                     /translation="MDLILDDRQDKLEVSEELIEKIKDIIIECLDYEGYDDNYEVSLS
                     FVDNKEIHELNREYRGVDRVTDVLSFPLLSDDFEDVELEEESLGDIVVSLERALEQSI
                     EYNHSFEREVCFLICHSMFHLLGYDHDTDENTKEMREKEEHILNKLNITRE"
     gene            86273..86992
                     /locus_tag="PC494_000467"
     CDS             86273..86992
                     /locus_tag="PC494_000467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HDF3910996.1"
                     /translation="MKPEKTRQGIIKAFNAAIEGILYTFKFERNMKIHYLGSVAVLII
                     SLFFNFSKLEMIMLLMSICLVVVAEMFNTAIEKAVDLVTDEYHVLAKIAKDVAAGGVL
                     VAALNSVVVGYILFYDKLTDISGILIYKIRESELHITLICILLVLIAVVVVKALTSTG
                     TPLKGGMPSGHAALAFAIATAITLMTERVVASTLAYIMAVLVAQSRIEGKIHTFWETI
                     AGALLGVLIAILVFQLGMFYN"
     gene            87111..87512
                     /locus_tag="PC494_000468"
     CDS             87111..87512
                     /locus_tag="PC494_000468"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HDF3910997.1"
                     /translation="MDNIELLRLAEDARQHSYAPYSGFRVGAALLTKSGKVYTGCNIE
                     CASLGGTNCAERTAIFKAISEGDKDIYKIAIASDNSENNEQTYPCGICRQVIIEFGSD
                     IKIITGYTKGEVFEHSIKDLLPNYFSGNDLK"
     gene            87576..88469
                     /gene="era"
                     /locus_tag="PC494_000469"
     CDS             87576..88469
                     /gene="era"
                     /locus_tag="PC494_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HDF3910998.1"
                     /translation="MFKSGFVSIVGRPNVGKSTLMNNVVGEKIAIMSDKPQTTRNTIQ
                     AVYTDEEMQIVFLDTPGIHKPKNKLGEFMVKAATEAFKNVDLILFVVDDSKKIGPGDR
                     KIIEDLRSVKTPIILVVNKIDQLDQKDELFDIIKMYDREGIFKEIVPISALKGKNTDT
                     LIKVIQNYLEEGPKYFPDYMITDQPERVLIAELIREKVLHYLNDEIPHGVAVEIEKMK
                     ARNDKEIVDVSAVIYCERDSHKGIIIGKNGRKLKGIGKSARQDIELLLGSQINLQLWV
                     KVKENWRNLQNYINNFGYNDK"
     gene            88481..89860
                     /gene="mgtE"
                     /locus_tag="PC494_000470"
     CDS             88481..89860
                     /gene="mgtE"
                     /locus_tag="PC494_000470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter"
                     /protein_id="HDF3910999.1"
                     /translation="MDRKLDASQDLLYEVKSLIDNNKVLELRELIEEYHIIDIFDIME
                     NLEEDMKIQLFEVLPLDMASSILEEGSVEFFISILSKLDVEHSKNILELMSLGDMADK
                     LSELEEEEREHIINLLNQENADYVKELLFYDEDSAGGTMTTGYISINKDMTALEAIDH
                     MREEAEEAETIYYIYVVDDEEKLVGVLSLRELIIARDANIVEDLMSENIISVYVDEDR
                     EEAVRLVSKYNLIAIPVVDRQEKLKGIITVDDIIDVMEEEATEDMYKFAGSSEHEREV
                     AEKENPTLREQIISALRGRLPWLIITLVGGLLASLILSNLDYIMNPVYAPLVFFIPVV
                     IGMGGNIGTQSSSVTVITLSNKDLNFSNVVREGIVGIITGLLCSIITGIVIYFVMRKL
                     DIVLIVSISLFINMVLGATIGAFMPVLLKKMDADPSTVSSPIISTALDITGIAVYFII
                     TTALLSKIV"
     gene            89933..90088
                     /locus_tag="PC494_000471"
     CDS             89933..90088
                     /locus_tag="PC494_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqzL family protein"
                     /protein_id="HDF3911000.1"
                     /translation="MNNISWEVFKKTGSIDAYLYFCDCKNIHEEIEEVREKKEDDDNP
                     EHPGDST"
     gene            90054..90827
                     /gene="recO"
                     /locus_tag="PC494_000472"
     CDS             90054..90827
                     /gene="recO"
                     /locus_tag="PC494_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HDF3911001.1"
                     /translation="MIILNTQGIVLKAIRYKESDIILTLFTRKLGKVSAIAKGAKKNK
                     SSLLSSSQLFSYSNFTLKKQGNMYKVTQSEIIKSFYNISYDIEAFSYATYITKLVENS
                     ILENQTNNRLFILLAQTLYLYTQDNTDNRFITAAFELKFLDYIGFKPIVNKCINCECK
                     ILQNSVFNIYEGGILCSKCSKLFDNNIKLDLTTISLMEYVLRNDILTCSKAKVSKYIT
                     HELENILDKYLKVYVDNINFKSLHVLQSVKNNKGVDNDE"
     gene            90820..91419
                     /locus_tag="PC494_000473"
     CDS             90820..91419
                     /locus_tag="PC494_000473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4342 domain-containing protein"
                     /protein_id="HDF3911002.1"
                     /translation="MSSNITIEMVDSVFERVPGATYAEAKEALVMCNGDVIEAVIYLE
                     NKKNTCNCKAKSAKETMEEVFGKDGENIKFQLKELLRKSSVVRIIVEKDGKTMMNIPL
                     TVGVVGLAFVPLATLVGLSAAVISKYRIKVQNEEDGEIVDLGELNEEKLHVLKNMITN
                     AAKDVKDVVVDKKEDDKDVTADLMKEESEKNKEDEDENK"
     gene            91579..92457
                     /gene="glyQ"
                     /locus_tag="PC494_000474"
     CDS             91579..92457
                     /gene="glyQ"
                     /locus_tag="PC494_000474"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HDF3911003.1"
                     /translation="MNFQEMILALQKYWSKQGCIMMQPYDIEKGAGTMNPNTFLRSLG
                     PEPWQVCYVEPSRRPADGRYGENPNRLYQHHQFQVILKPSPDNIQELYLESLKEIGID
                     PSEHDIRFVEDNWEAATVGAWGLGWEVWLDGMEITQFTYFQQVGNIECELETGEITYG
                     LERLAMYIQEVDSVYDLKWNDKITYGEVFNKAEYENSMYAFELCDADMLFNLFDIYEK
                     EALRLMENGLVIPSYDYVLKCSHAFNTLDARGAIGVSQRASFIGRVRNMAKTVAETFV
                     KQREEMGFPLLKDGDK"
     gene            92457..94523
                     /locus_tag="PC494_000475"
     CDS             92457..94523
                     /locus_tag="PC494_000475"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HDF3911004.1"
                     /translation="MKNYLLFEIGVEEMPSRFVGSTLEQLKNNLSKLFDENRIAFDKI
                     NAYGTPRRLTLVVEGLSDRQNDLEEEIKGPAKKIAVDAENNLTKPALGFIKSKGLSES
                     DIYFKQVGKEEYIFATIKQDGKETSEVLKDILPETIKSVVFPKAMRWGGKNLKFARPI
                     RWIVALLNDKVLEFDLEGIISSNVTKGHRFLGESTIEVDSIEDYFEKLEKNYIVLDQN
                     KRKEMIRKQCIEVANSLGGEVEFDEDLLEEVTYLVEYPTAFYGEFDVDYIKLPKEVVI
                     TPMKQHQRYFPVLKEGKLLPNFIAVRNGDSYRIDNVKAGNEKVLEARLADALFFYRED
                     TKRNLESYIEKLKTVVFQVKLGTIYDKTLRLEKLSADILDSLGLVDEKADTIRAAKLS
                     KADLVTGMVGEFDELQGFMGKEYAKVGGENDVVSEAIFEHYLPRFAGDILPKTNAGVA
                     LSIADKLDSIAGFFAIGIQPTGSQDPYALRRQALGILSILMDRKVAVDIKVLIEHALD
                     NYSELDFDKEEVVEQIMNFFNERVKNLFKDLGIRYDVVDAVLSSDINDVSDMHMRALE
                     LNNWLEKDELVEMLTAFNRVSTLAQKAESDKIDESLLKEDAEIKLYNEFKQVKIKVNE
                     LLKDKKYGIALDEFASLRPVVDNLFDTVMVMDNDEAIKNNRLALLKQVYDTMLEICDL
                     SKIVYK"
     gene            complement(94689..96236)
                     /locus_tag="PC494_000476"
     CDS             complement(94689..96236)
                     /locus_tag="PC494_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrite/sulfite reductase"
                     /protein_id="HDF3911005.1"
                     /translation="MDNFKKILLNELPNFKEYSSKFLNGEINKMQYKGFSGGYGVYAQ
                     RDKKSFMIRLRVSAGVLSQYQLNKIYEIAIKHNLDKIHLTTRQAIQLHDLSINSIVDI
                     MEEGIKNDIFTRGGGGNYPRNVGLSPLSGVDPSEVFDVTPYAVATDKYFIKNATTYHL
                     PRKLKVSYSNCYTDTAHCSIQDLGFVATLKNDEPYFRVFLGGGLGKQPKVALELDELI
                     KPKDALYCVEGMIKFFMDYGNYENKNRARVRYMVESLGEELFLEKFKEYYKLEKENGS
                     LELNIEEIDYSKPGVKIDIQDSRLIPQKQDGLYTVYIHPVGGILLTKDLSTLLKELDN
                     VENPMIRLGMTEGLYILNLNGNEAKRILEISKTISCNSQLEQSISCIGVPICQMGIQN
                     SQKMLHEIIDYFRLQNNEEILNKAPKLYISGCLNSCGVHQVGSIGLCGKKKNVDGIST
                     DTFELFVGGSFEIGKTRLGKSLGDFKASDIPEMLYKISDASSGNFYEWVNSNDNILNK
                     ITDKYKI"
     gene            96516..97283
                     /locus_tag="PC494_000477"
     CDS             96516..97283
                     /locus_tag="PC494_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IclR family transcriptional regulator"
                     /protein_id="HDF3911006.1"
                     /translation="MGEIINALDRALDIILLLYHEKREMGITEISKAMGVYKSTVHRT
                     LVTLENKGFVIQNAENGKYWLGINLYAIGMVVGEKMSLTEIVKPYTKKLNQEFNEVVN
                     VSILEERAQDSPRSIIIHKEYGSNQLLSVNPSVGSSSECYCSAVGKCLMAFNDSIDFE
                     KYRKTPIHKYTEHTIDNWDDMMLFLAKIKEQGYAIDDEELEHGLTCIGAPILDKNNKA
                     IAAISLSGPTIRMREGDFEYKIKRVIETAKSISELFR"
     gene            97566..97763
                     /locus_tag="PC494_000478"
     CDS             97566..97763
                     /locus_tag="PC494_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HDF3911007.1"
                     /translation="MEKVKLSVERCKGCYLCIEACKKDAISLSDYTNKKGFVTIKVDE
                     EKCIQCGACYTMCPDLVFEIL"
     gene            97792..98868
                     /gene="vorB"
                     /locus_tag="PC494_000479"
     CDS             97792..98868
                     /gene="vorB"
                     /locus_tag="PC494_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-methyl-2-oxobutanoate dehydrogenase subunit
                     VorB"
                     /protein_id="HDF3911008.1"
                     /translation="MQSLLIKGNEALAEGAIRGGCRFYAGYPITPQSEILEMMAWRQK
                     EVGGVFIQGESEIASVNMVMGASALGARAMTSSSGPGFSLKQEGIAYWVSAGLPAVVA
                     CVQRYGIGDGFIGAGQDNYWQAVKGGGNGDYHLIVLAPNSVQENMDMAYESFELAEKY
                     MHPVLILSDATIGQMVEPCIAPPMKEYDMDKAPWAAKGTPVGEKNKVITDITYFEDQD
                     TWQKGYIEKMRKVQEDEQRWEEIEIEDAEVVFVAYGISSRIAEGAVRDARAKGMKLGL
                     IRPKTLWPYPRKAFKKLSDSLKGLVTVEMNMMAQMKEDVIIACDNRFPVYSVATAQYM
                     AEVNQLIDFAQQIIDGKAKQEEVF"
     gene            98871..99590
                     /locus_tag="PC494_000480"
     CDS             98871..99590
                     /locus_tag="PC494_000480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoglutarate oxidoreductase"
                     /protein_id="HDF3911009.1"
                     /translation="MAKKAPAIMMCENMFCGGCGHSIVDRIIGEVLTEMDICQDTIIC
                     SDIGCNHMFQFSMNVDVVVPPHGKMGAAMAAMKRVRPDKYIFTIAGDGGAYAIGLGET
                     MSAATRNDNVIFLVMNNNMFAMTGGQMAPTTIEGQYTASTPAGRNYADHGSTFDVVKV
                     MGNLDIAYLARGTITNPKEINTTKRYIKKALEKQKEKKGFCLIEVLVPCPTNWGLKPV
                     DAMKRIENELVPKYPLGEFID"
     gene            99603..100142
                     /locus_tag="PC494_000481"
     CDS             99603..100142
                     /locus_tag="PC494_000481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoacid:acceptor oxidoreductase family
                     protein"
                     /protein_id="HDF3911010.1"
                     /translation="MLNEIICAGFGGQGVLTAGKIIMYVAYKAEKKITWFPSYGNEMR
                     GGSANCNVVVSDEKIANPCVKNPDILLGMNSVSVDKYESLMKKNGYMFVNESLVSKDR
                     KYREDINVIKVPVTEIAQNLGNEKAANICMLGAMVKSLDLFTKEEFESGMCEYFENQG
                     KGKFNSKNVEAFEAGYDYE"
     gene            100299..101357
                     /gene="buk"
                     /locus_tag="PC494_000482"
     CDS             100299..101357
                     /gene="buk"
                     /locus_tag="PC494_000482"
                     /EC_number="2.7.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="butyrate kinase"
                     /protein_id="HDF3911011.1"
                     /translation="MKVLVINPGGTSTKISVFQDENEILKKNITHTREDLKNFSKVFD
                     EYDYRKQLIVDILSSENHSINSFDAVVGRGGLMKAIKGGTYTVSEEMIEDMRNEINGE
                     HASNLGALLAKTIADEIGVQSFVVDPVSVDEFDDVSRITGISDIEKASWLHALNHKAV
                     SRKIAQKLGGKYEDYNFIVAHLGSGISIVAHKQGKMIDGSGGRSDGPFSPERSGGLLA
                     YPLIELCYSGKYTHDEMVAKVSSIGGMYDYLGTKDMIEIENRIKDGDEKAKLIMDAFI
                     YQVAKEISMYGASLSGNVDRVILTGGISHSEMVVKGVAEKVSYLAPIEIVPGEMEMEA
                     LALGALRVLNGEEIAKTY"
     gene            101375..102268
                     /locus_tag="PC494_000483"
     CDS             101375..102268
                     /locus_tag="PC494_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional enoyl-CoA hydratase/phosphate
                     acetyltransferase"
                     /protein_id="HDF3911012.1"
                     /translation="MLKDFNNLLEEAKKLEPVIVSVAVAEDKEVLKAVKSATDLNIIK
                     PILVGDKDKIESISREIGLKGHEIIGCQNPDESVKKAVEIVKNKEAKVLMKGLVNTSV
                     YMRAILNKETGLRTGRLLSLLAVYELPQYHKLLYCTDSGINVSPNLNQKKDIMTNALL
                     TMKSIGMENPKTAILTANEMVDPKIQSTVDANLLVEMEKSGEIPKCIVEGPIAFDVAF
                     DAHAAEHKGIKSNIAGDVDLLVFPNIEAGNILGKSWLRFNKAKWAGIVLGATNPIILG
                     SRSDTAEIKINSIALACLASQ"
     gene            102298..103506
                     /locus_tag="PC494_000484"
     CDS             102298..103506
                     /locus_tag="PC494_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HDF3911013.1"
                     /translation="MKYAKRMDMVKASAIRDSQKKIAQKVASGGTVISFAAGLPDPNL
                     FPIEEISEITQKVLNERGKFALAYGPTKGEDELLDLLVKRMKEEENIDTKAENIIITT
                     GSQQGIALSAMILLEKGDVVVTENPSYLGAINAFRPYECDFLGVDTDEEGMVTDDLDK
                     LLSENSNIKVIYVIPTFQNPTGKTWSLQRRKDFMEVVNKYDVIVIEDNPYGEIRFTPE
                     PLPTLKSLDTKDKVLYLGSFSKVLCPGFRVAWMCGNVDIIDKAELLKQGIDLQSNQFS
                     QVQVIEFLKKYNLNEHIEKIRAEYKKRCLLMLDAMKKHFPEEAKYTEPDGGMFIWVEL
                     PESINVDDLLDKAIDAGVAYVSGESFFANNGPKNTMRLNYTTMSEEQIVKGVEILAEV
                     IKKELNYACE"
     gene            103530..104789
                     /locus_tag="PC494_000485"
     CDS             103530..104789
                     /locus_tag="PC494_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDF3911014.1"
                     /translation="MGEKENGIKFGKLMFQLVIIAISWELVYIIPFIQYTLYDPILKA
                     LECTNTQLGFLLTIYGLGNIFGAPIGGWLADRFDYRKIILGSVFLNGVVSFLFAFNMN
                     YPFAVATWVGCAITSLVMNYPSMVKILRVIGKDNQGKVYGFNEAMVGVSGVVMGAIFL
                     YIYTCFATPTLGMRWVMISLGILSIAMCPVLWFVIKDVDIKEEREEAGEKMSAGDFIT
                     VLKSPNTWLVGISIFCVYSFTVTMSYFTPYITSVLGGSVALSGALAIIRQHGLKLFGA
                     PFGGYCADKLKSPTKVLLPIYVFGIAVIVLFLVLPASTPMTIFIALTFVVGILGYMGK
                     GIYYAVQDEVKVPVKYSATTIGIAAALGFSPDVFQFALIGHWIDTYGNKGYTYTFIFQ
                     IAILVIGILSCLYILKVKKRRASKLEA"
BASE COUNT        41625 a        11232 c        18536 g        33730 t
ORIGIN      
        1 tttattgtat gcaattgttg tatttttagg ttttttgtga ttaattaaaa aattataaaa
       61 atcgtttaca tgttgatttt taaaaaaaaa agatatagaa ttatatagaa agtaataaac
      121 aaaaattgga tttacgggag tggaatgaaa tgatgaatgt taccttaaca gatgtgaaag
      181 aggctagaga gaccattaag aacatagtaa aaagaactga cttacttgaa agtgttaaac
      241 ttagcgaaaa aacaggagca aatgtgttct ataaatgtga gaatcttcaa aaaacaggtt
      301 cttttaaatt aagaggagct tgtaacaaaa tagcgagttt aacagatgaa gaaaaggcaa
      361 atggagttat agcttcaagt gcagggaatc atgctcaagg agttgcattg ggagcaaaaa
      421 tgactggtat aaaatctaca atagtaatgc cagcaactgc gcctttagca aaagttagtg
      481 caactaaagg ttatggagca gaagtagttt taaatggtgc ggtttatgat gatgcatatg
      541 caaaagctgt tgaaatacaa aaagaaacaa gagcaacttt cttacatcca ttcaatgata
      601 agtatgttat agcaggacaa ggaactatat ctcttgaaat tttcgaacaa ttagacaata
      661 aagttgatac tatactatgc ccagttggtg gaggaggaat catctctggt gttgctgttg
      721 cagcaaaagc attaaatcct aatgtaaaaa tagtcggtgt tcaaactgca aatatacctt
      781 caatgaaaga gtcaataaaa aatggaaaag taacaacagc atttaatgat actacaatag
      841 ctgatggtat agctgttaaa actccaggag atttaacttt tgaaataata aatgaattgg
      901 ttgatgaaat agtagtggtt gaagagacag aaattgcaga atcaatatta tttatgatgg
      961 aaagtcaaaa aatagtttca gaaggtgctg gtgctgtatg tacagctgct atattaagtg
     1021 gtaagtatgt accagcaaaa gatgaaaatg tagtttgtat aatatctggt ggtaatatag
     1081 acataaatac gttatataga ataataggtg ttgctttagc taaagaagga agaagatatt
     1141 catttagtac aattatggaa gataagccag gaaactttgc tgagttaact agaataataa
     1201 gtgagaatgg tggaaacatt ttaagtgcta atcaaggtaa attatcagca ggggaagctc
     1261 taggaaaaca aagtgcggaa tttatattag agacaataga ttatgaccat atagctagaa
     1321 taaagaaagc tatagaagaa aaaggtttta aaattataga attataataa aaagtgtata
     1381 taatatacaa gaaaaatagt ataatagtgt atgaagatac attttatgtg tattagatta
     1441 acgaattagg aggattttaa aatgaaacat gaagtaatac atactaatga tgcaccagca
     1501 gctttaggac catattctca agctataaaa gctggaaact tgttatttgt atctggacaa
     1561 gttcctcttg taccagagac tatggaagta gttgaaggag atgtacaagc tcaaactgct
     1621 caatctttaa aaaatcttaa agctatatta gctgaaagtg gagctgattt ttcaaatgta
     1681 gttaagacta cagtatttat aaaagatatg aatgaatttg gggctataaa cgaagtttat
     1741 gctgaatatt ttggagaaaa taaaccagca agagcttgtg tagaagttgc tagattacca
     1801 aaagacgtta aagttgaaat agaagtaata gctgtattat aaaaatacaa tatttttaat
     1861 ttgaaaaggc tgaaaaacta tattctagtg attcagcctt tttataaaaa aataaatcac
     1921 aataaagaac atgataaata ttgtcgaatt aaaaaataaa attaaaataa atattgcaat
     1981 atttttgaga aggttttata atgagtatat aatttgaaac gtgtaactat taaattaggc
     2041 atgagttctt ggatattttt atcctgagga ttcatgcctt ttttgtattg aaattcaaaa
     2101 atctatttaa taaggaggaa gtactgtgtt aaattttttc aagaaaaata aaagctataa
     2161 gttacatgca gtagtgagtg gtaacagcat taatattgag aaagtaaacg attctgtgtt
     2221 ttcaaaaaag ttaatgggag atggagttgc aattattcct aatagtaatg ttgttgtagc
     2281 cccttgtaat ggtaaagtaa ctgtgcttac agaatcaaag catgcctttg gtatggtctc
     2341 agatgagggt gttgaaatat tagtccacat aggaattgat acagttagtt tacagggtga
     2401 ggggtttaaa aatgaagtgt ctcaaggaga tactgttaaa aaaggtagtc caataataag
     2461 ttttgaaaga gaaaaaataa attctcaggg aattgattgt acaacaataa taattgtatt
     2521 aaatcatagc gaattttcag aaataaattg catggtagaa aatgaagttg ttgcagggca
     2581 agatactgtt attgaaatta tgaaataata ggaagggatt aattcaatat gagagtagta
     2641 aaaatcttta ataataatgc attatctaca gtaactaatg ataggaaaga agctatttta
     2701 ctaggtcttg gtataggttt taataaacgt ccaggagata aagttaatga agataaaata
     2761 gaaaagattt attatgttca agaccacatg caaacaaaat ttttagaatt attaaaaaat
     2821 gttagtccag aagtgatgga tgcttcacaa caaattataa gtcttatacc aggaaatgag
     2881 ggaaaattta ataataaagg gatattatct ttagtggaac atattagttt tgcaatagat
     2941 agaatgaaaa ataatgtttt tttacctaat ttaatgcttt tggatataaa gatgatgtat
     3001 tcaaaagagt ttgaattagg agtaaaagct ttagaaatta tatatagagt atgtcatatc
     3061 catttgcctg aagatgaagc aggttacata gctttacatt ttgtcaattt acaatcaaat
     3121 gataatttgg catatgatac tttaaaattt gtaaaaggta gtattgattt gattaaagaa
     3181 tgttatggat tagaattaga cgaatcgagt ttaagtacat tacgttttag aactcatctt
     3241 aaatttcttg ctcaaagaat ttttaagaat gaaatttgtc aggatgataa aatgattgaa
     3301 atgtatgatt atttaattaa caatcatcct aaaaataaag aatatttaga aaagttaaat
     3361 gtatatattg aaaaggagtt taggtataaa ttagataaac ctgaaaaaat ttatctacta
     3421 ctacacctaa caaaaatctt ataagaatga gatgaattag taatagaaat atataatttt
     3481 agggggggat aagattgaaa gaaaaactac ttggaggact ggaaacattt gcaaaggcaa
     3541 tggttcagcc attaatgtat ttatcgagtg caggaatatt aatggtggta ggtgtactac
     3601 ttacaaatga tatgttatta ggagtacttc cattttttaa atgggagcca attcaaatat
     3661 ttggaagcct aatttataac tgtataatgg ctattattaa taatcttgct gttatatttg
     3721 ctataggtat tcctgctgca ctagcaaaaa aagagaagca caaagcagcg ttaataggat
     3781 ttatgagtta tataatatac cttacagctt ccaacactat gttaacatca ctaggtcaac
     3841 tagcaaaaga aagcaagatg cttggactga tagggactgg acaagctact attttaggta
     3901 ttcaagttgt agatacaagt gtatttggtg gaattatttt agggtgtata gctggatatg
     3961 tatttaatcg tacaagcaac aaaacattta aaggagcttt acagatatac tcgggagcaa
     4021 attttagttt tatatgcatg ttctttgtat ccattttaat tggagttgtg agtaacttta
     4081 tatggccatt agctcaacaa ggaatagctt ctcttgcaaa tgtcatcaaa gatacaggta
     4141 catttggttt attcttatat ggttttttag agagaatatt agtaccaact ggacttcatc
     4201 atttaatcta tacaccattt cagttttctg atttaggagg agtgcttaaa gttggtgcag
     4261 atacagtttc aggagcctat gctatagtta tgacagaaat gaatttacca gttgagcgtt
     4321 tctcagatag tatatactac atggcaactg gatttacaaa gatgtttggt tatataggta
     4381 taggagctgc ctttatttat actgcatata agcaaaataa gaagaaagtt aaggcaacga
     4441 ttattccact aataattacg gcagtattag cctctgtaac agaaccatta gactttatgt
     4501 ttgtattctg tgcaccattt ttattctttg tacatgcagt tatagctggt ctttttatag
     4561 ctttattaaa aatatttgat gttactgcat tatgtggagg gaacttatta gtatcaatta
     4621 taatgaatac tacagtaggc gtagaaaaaa cacactggcc agtaatgatg atattaggac
     4681 ttgcacaaat tattgtatat tttgtagtat ttagtttttt aattaagaaa tttaattata
     4741 aaactccagg tcgtgaagat gagagtacag ctacaggcga agaacaatca aaacaactta
     4801 atttagatgc agggatagaa aatataattg atgggttagg cggaaaagaa aatattaata
     4861 cagtagaaaa ttgcatcact agattacgtg ttaatgtaaa agatgaaagt aagattaatg
     4921 aagatataat taatttaacg ccaaatagcg ggattgtaag gaaaggaaaa gatatacaaa
     4981 taatttttgg acttcatgtg catgaggtaa gacgtgcagt agaagatttt ttagaagctt
     5041 attaaagata tatatttata tagcaagggt aaataacagc tttaagtgct gtttactatt
     5101 tattaaagat acatataatt tatagaggag gaataattat tatgattatt actattgttg
     5161 gtggaggaag cacatttact ccaggtattg ttaagtcaat tgcattaaga gaaaaagagt
     5221 tagagcttga ggaaattcgc ttatttgaca ttgataaaga acgccaagat aaagtagctg
     5281 tagttgtcaa ctggatacta aaagaagatg ttaaaacaga tgttaaacta actgtaacta
     5341 attgtgaaaa agaagcgtat acagatgcta catttatatt tgcacaaatg cgtgttggta
     5401 aatatgaaat gcgtgagcag gatgaaaaaa ttccattgaa atatggttgt gtaggtcaag
     5461 aaacttgtgg ttgtggaggg atggcatacg gactgcgtac aatacaacca atgataaagg
     5521 ttattgatga tgtagagaaa tatgctaaaa aagattattg gatattaaat tactctaatc
     5581 ctgctgcaat cgtttctgaa gcttgtcgta agttaagacc aaatgcaagg attataaata
     5641 tctgtgatat gccaatagct attatagata tgatagcggg gtcattaaat atcaatgacg
     5701 ttcataatat acgctatgat tattttggtc taaatcattt tggctggttt acttcaatag
     5761 attataaaca tagagactta atggaagaga ttaaggaata cataaaagaa aataaaatat
     5821 tattaccaaa atcttatata gaaaacttaa ataaaagtcg tagtacagga aatcgccatg
     5881 ctgtaagtag ctggatacat gtttgggaat ctgtttatac aatgttagaa agcttcccaa
     5941 aatatctgcc aaacacttat ttaacatact atcttttaag taaagaaaca gtggaacatt
     6001 caaacataaa tcgtactcgt gcaaatgagg ttatggaaag ccgtgaaaaa gacttatttg
     6061 aaggtgtgag acattactta gaaactggag aaatttctga aaaagcattt tatgcaggtt
     6121 cacatggaga ttggattagt gatttggcag tttcaattaa aaatgataca cgtagtcgtt
     6181 ttttagttat aactgaaaat cgtggagcta taccaaacat gccatatgat gcaatggtag
     6241 aaattccagc atatattggt aaagatggtc cagaagttat tgctcgaggt ccaatacctc
     6301 tatttcaaca aggattaatg atgcaacaac ttaacagtga aaaattgata gtagaagctt
     6361 atatagaaaa tagttatgaa aaagctttac aagcattcac attaaataaa actattccaa
     6421 gtatgaatgt tgctaaagaa attttggatg aaatgataga agttaataag gaatactggc
     6481 cagaattaag atagtaggat aaaggaaagg gtttttattt aataattaga tatgttttca
     6541 gagtctttta tcaaaatgta ttcacaaaca tatggcaata tattaaaata aagagtgata
     6601 tttttagaag aatggggtga tgcaatgaac attataaata aaattttttg ggaagaagat
     6661 aggattggca tgattacaaa taatttagag gcagatacac atagccactg tatgttacaa
     6721 ctgttcttag ggatagaaga cagcattgaa ataacagtca atgaaaaatt agttaaatgt
     6781 aattgtatca tagtagataa aaatatctct cattcatttt cagcaagaaa aaaagtttat
     6841 tactctgcta ttattgaacc tacatctata tatgcagaac agcttacctc aaaaatgaat
     6901 gattttggct actggatatg tgacaatgat ggattagaga aattacgtca acaaggaact
     6961 tttttgatag ataactctag taaagaacaa tatttaagat ttatggaaat gcttaataac
     7021 tatttgaata tacctataac tctcaaacat tatgatgaca gaattactga attgctcaat
     7081 ttattacgta cttgtaattg tgataatcat actatttcaa gttttgcaga taaagtgtcc
     7141 ctatcagcaa gtagattatc acatctgttt aaagaacaaa tagggatacc tttaaaaagc
     7201 tatatcttat ttcatcaaat ggagtgtgct tttagagaat tactttctgg gaaaaatgtt
     7261 accgaagctt ctatgactgc tggattcgat actccatcac actttgcagg gacagttaag
     7321 cgaatgatgg gaatgcctgt ttctttatct ttgaaagata gcgaattttt gaaagtatat
     7381 taaatattct cgttatataa tgaagttgta ctaagaaagg ggctttgtta tgaataaaga
     7441 atatttagag gaaacaaaaa tgttaaatta taatgaacca caacttaagc ttttggtatc
     7501 atcaaagaat tggttggaat tagatgattt tcataaaata aaatctattt atgagtttgt
     7561 acagaatgat attttatttg gatataatgc ttctgatatg ttaagcgcaa cacaggtatt
     7621 aaatgatggt atgggacaat gcaatacaaa agctactctt ttaatggcat tattacgtgc
     7681 agtgaatatc ccttgtaggc ttcatgcttt tgatgtaaca aaagattttc aacgaggagc
     7741 tacatccaaa ttgatttcac tattagcacc aaaatatatt cttcatactt gggtagaggt
     7801 attttatcaa gataggtgga ttgctcttga gggtgtcata actgataaaa aatatttaga
     7861 agcaattcag aagaaatttt ttaatcatgg tggaacattt aaaaagtatg caatagctac
     7921 aaatgatttg aaaaatacat ctattgattg ggatggtaaa gatactttta tccaaaaaga
     7981 agctatcgtg tatgattatg gtatttttcc atcaccagac gtattttttt ctactcattc
     8041 acaacatatg tcaaaattaa aaaatttcat atatgtacat cttatcagaa aaataatgac
     8101 aaaaaatgta tgtaaggcta gaaacaatta tattgataaa aacgaatgag tgtttaagag
     8161 gtaactatat aggaaatata tagaataatt aaaactgtac tggttaaaat gaataaaaag
     8221 gagttatcac agagcaaact taaattgttc ataggataac tccttttctg tattaacttc
     8281 taataatttg atgtcttttt ataaaacata tagatacaat taaaccagta aatgcaagag
     8341 tagctgctat tgaaaatgca acatctattc catgaatgtt agacagcatg tttgaactca
     8401 tatgagcttt cttagtagca cttgtcatta tagtaataag tatagcagaa cctatagctc
     8461 cagatatctg acggagtgtg ttattaattg ctgtggcatg agatataagt tctctatcta
     8521 atgttttaat tccccatgta gttaatggca ttaaaaccat tgaaatacca atcatacgaa
     8581 tacaatacat caatgacaca tgaattaaag atgtatctct gcctaaaaaa gcgaaggata
     8641 aagttcctaa aaacaaacat cctgttccta atattgatag agcatgaggt ccatatttat
     8701 ctaaatgacg tcctgcaatt ggattgagta caaccatcaa tatagcacca ggtaacatta
     8761 atgaacctga agataatgca gaaaatcctc ttacagattg aacgtacaga ggaatcatta
     8821 atgtagcaga catcattgag gcatatacaa tcataattaa tattgtagaa ataagaaatg
     8881 gtttattttt aaaaaccctc aattctaaaa aaggttcttt agattttaat tgacgcaatg
     8941 taaataaaat taatgacata attcctatta atattggtaa atatgtggca atattagtcc
     9001 acccataatt accttgatta gtaaatccaa ttaataaacc accaaaacct agagatgata
     9061 gtactattga aggtatatct aattttagtt tttgagtttc cccaacattt cttaatagaa
     9121 taaatgatag tataacatct aatatagcaa taggggaaag aaacagaaat aaactatgcc
     9181 aaccaaatga atctactaac catcctgata aagttggacc tattgctgga gcaaatccta
     9241 ctgtaatacc aactaaactc atagctgcac cacgtttttc ctcagggcat aaatagagta
     9301 taataacttg taaaagtggc attagagaac cagaacccat tgcctgcaac acacgagcaa
     9361 tcaacatagt tgaaaaatta ttagaaaaaa gtgcaataat acatcctata gaaaagatag
     9421 acattgatgt aataaataac tttctagtac taaatcgatt tattaaataa gctgttgtgg
     9481 gtacaataat acctgcaata agtagataaa ttgttgttaa ccactgacca atatcagcag
     9541 taattttaaa atctgacatt atattaggta atgctgttga caatagtgtt tgactgagag
     9601 aacttataaa agcaccagtc attacaattg ctattattaa atttcctttt ttattgttac
     9661 tttgggtttc cataatttat aacgtctcct tttttaattg atttttaatg ctgttcaata
     9721 aaagtacttt tggtcttaaa gtgtcttctt tttctaaata tgcaatcatt gcatccataa
     9781 ttaaagaatc atattgttga ttttttcctt cgacgtataa tttttttatt gcttctagta
     9841 atttaggatt ttcaaggaga gaagtatcag ttttgattag ttcttctata tcttgtatcg
     9901 ttttaaaaaa tagcgattta ttatgaaggg aaaagtaaac ttcatcttct tgtttatgta
     9961 aaaacattga tttttcaatt aaaggattta gattatccat attttctaca actaaatcta
    10021 gaatttgtat agtaaatttg gcaataaagt atacatttat ttctcttttt tgtacatgaa
    10081 taatgtatat aaactgatga attagagcat ccaataagaa aactaaatca aatataattt
    10141 tttctatttt atcaccatag ttatcaaata agcttagttt gtattcattc aataagttag
    10201 ctcttgattt tgtttgcaat ttacttgtag ccttacgttg ctcttcagaa aagttttctc
    10261 ttatataggt atttatggta gttctagaaa aaatattttt ccatacagca attatctttc
    10321 tgtttaactt ttctgatgat ggaatgtcat tattttcatt tatggaatgt ataatttcta
    10381 aaaacttttc atcataataa ttgattattt cgcagataaa actttcctta gtttcaaaat
    10441 gcttgtaaaa agtagcttta gacattttac actcttttac aacatccgat attgaagtat
    10501 tttgaaaacc tttttggtca aaaatttttt gtgcaatagt tataatgagc ctttgttttt
    10561 ctgtcacttt attatctcct ttcacgcaaa aacgtttagt actatatagt acctacaagt
    10621 tttgataaat atattataca tcatttggaa aaaaaatcaa tatatagact gtaatatgaa
    10681 atttttgaaa aatttgttgt tatttttagt cgtataaaaa agaaacttaa gagtttctta
    10741 agaattgttt aaagaagttg caataaatta gtggtatgat tatagtatga aagagaatgt
    10801 cttgaaattt ttctgtatca aattccaatt atggaggtgt agtatatgaa aaagaaaatt
    10861 tgtgtagcaa taatttttgc tctatttata gtttttgtag aaatgtttat tgatagctct
    10921 agcgaaggaa gtaaaattat gacagctgaa ttaagtaaat acaggaaagg cgtaaatgta
    10981 ttatcaataa acaatattat agtagcgaat aaaaaatata gtttgcccaa agattattct
    11041 cctcaggaaa gcagtgaagc gagagatgct ttttataaaa tgaataaaga tgctcaaaag
    11101 tcaggattaa atttaaaagc ttttagtaca tatagaagtt atgaatatca agatagatta
    11161 tttaagtcat atgtaaaaga acatggagaa aaagaagcaa atagattttc agctaaacct
    11221 ggagagagtg agcatcaaac tggacttgct tttgatattg gaggagatga ccagtcttgt
    11281 tgggcaaata aaaagttcaa caatacaaaa gaagctaagt ggttgtatga aaatgcatat
    11341 aaatatggtt ttatacttag atatccagaa ggtaaagaga atataacagg atatatgtat
    11401 gaatcttggc actatagata tgttggaact gaacatagca aaaactttgc aatgaataat
    11461 ttgactttag aagaatattt acatataaat taagagatgg tttgttaaaa ttaggttaaa
    11521 ataaaaaata acctagacta ttagctgtgt aaagtgatat aatgtaaata caatttaaga
    11581 taactactcg aaggggagta gcttacacga aagtggtaat taatcgtcaa gacagtagaa
    11641 atactcggtt aattagcaag ggattccttg atagcaagac cttcaaaata agcattaggt
    11701 atgtttgttt tggggtcttt ttttattcaa ggaattttta tttaaaaaaa tttaaatttc
    11761 aagtatacat aagagccccc aaacataaaa taaatttatt gaagaggagg gcaacaaatg
    11821 tcttacaaaa gtacttatca agaagtaatt aaaaatttag actcaagttt atctggtttg
    11881 agtaaagaaa gagcagaaga gttgttagaa aaaaatggag ctaatgaatt aaaagaagca
    11941 gataaggttc ctacttataa gcttttccta gaaagtttta aagacccatt agtaataatt
    12001 ctattgatag ctgctttagt acaaatattt ttaggtgaaa cagtggagtc tataataatt
    12061 tttgcagtta ttattataaa ctctgttctg ggtgttgtac aaacaaaaaa agcagaaagt
    12121 tcattagaaa gtttgaaaaa tttatctgca ccaaacgcaa aggtaataag agacaataaa
    12181 aaaatgacaa ttccagcaaa aaatctagta gttggagata ttgtattctt agaagctggc
    12241 gattacatac cagcagatgg aaggcttata gaagcacaat ctctcaaggt tgtagaaggg
    12301 atgttaactg gagaatcaga accagtttta aagcatatag aaaaaataag tgaagatgta
    12361 agtttaggtg accagaaaaa tatggtattt agtggtgctg tagttgttta tggtagaggt
    12421 tcttttgtag tgactggaac aggtatgaat actgagatgg gtaaaatagc tgggctttta
    12481 gaaagtgctg aaaataaact tacaccattg caacaaaaaa tagaggattt tagtaaaaaa
    12541 cttggtgtag gtattgtaat acttgctctt ttaatattta taattcaagt agcaagaaat
    12601 tactttatgg ctggaaatgg agaaatgaca caaattattt tagattcatt catgttctct
    12661 gtagcagtag cagtagcagc tataccagaa gctctatcat caatagtcac tatagtattg
    12721 gctgttggaa caaatagtat ggcaaaaaaa caagccataa taagaaaatt accagcagta
    12781 gaaactttag gttcaacaag tgtaatatgt actgataaaa caggtactct tacacaaaat
    12841 aaaatgacag tagttgatta ttatatgtat ggaactaata atgatgagtt agataaagaa
    12901 aaagtaaact attcttatca tgctaaatta ttgactatgg tttctacatt gtgtaatgac
    12961 tctcatataa ctagtgatgg taaagaagtt ggtgacccaa cagaagtggc tttaataaat
    13021 tattcaagta aaaatgattt agattatgat aaattaagaa gtaagtatat cagaataaat
    13081 gaaataccat ttgactcaga cagaaagctt atgtctactg taaatagtat atatggagat
    13141 tatataatgt ttacaaaagg tgctccagat attgtgttta gtagatgtaa atatgctttg
    13201 aaaaatggtt caaaagtaga tataacagat gagataatag aagaatataa acataaaaat
    13261 gaagagttct caaatagagc acttagagta ttagcttttg caataaaaga tgtcccagaa
    13321 gaagatttta taccttcaat tgatgacgaa catgacatga cattggttgg aataatggca
    13381 atgatagacc caccaagaga agaagtaatg gatgcagtaa aagaggcaaa gagtgctggt
    13441 ataaaaactg ttatgataac tggtgaccat aaaacaacag cagcagcaat tgcaaaagag
    13501 attggtataa tggaagaagg agacttggct cttactggaa aagagcttga tgctttgagt
    13561 gaagaacaac tatatgaaaa actagaaaat ataagtgtat atgccagagt ctcgccagaa
    13621 aataaaattc gtatagtaaa agcatggcaa cataagaata atataacagc aatgactggt
    13681 gatggtgtta atgatgcacc tgcattaaaa caagcagata taggaatcgg tatgggaagt
    13741 ggtactgatg tagcaaaaga tgcttctgct atggtattgg ttgatgataa ctttgcaagt
    13801 atagtaaatg ctgttgaagt tggtagaaca gtatacagta atataataaa atcaattact
    13861 tatctatttg caggaaactt aggagctata gtatccatag tatttgcagt gtttgcaggt
    13921 tggtcaaatc catttacagc tttacaactt ttgtttataa acttagtaaa tgactcttta
    13981 ccagcaattg cattagggtt tgaaaagtca gaaaaaaata taatgaataa acctcctaga
    14041 cacccggatg aaagtatact agcaggagga acattgaagg cagttgctat aagaggttgt
    14101 ataataggtg tagttacaat aattgcacaa tatataggat tacaagtatc tccagaactt
    14161 ggagtagcaa tggcattttc aacattgata ttagctagaa taatgcaaac attacctgca
    14221 cgttctaata atcaaacagt aataaaatta ggttttttca gcaataaata cgttatagga
    14281 gcagttttag tctgtcttgg gctttactct ttaacactaa taccagtgct aagaggaata
    14341 ttctctatac caacaacgtt tggattgtac cagttgggga tttgcctagg gttagcatta
    14401 atttcatcaa tattaatgga acttaacaaa ttaataaata gaagtgaagt aaaataatca
    14461 aaaaattaaa gggcatattg attttaacaa tatgcctttt ataaatagtc taatttattc
    14521 tatattatcg attatttgga atgcttttat aacttcaggt aattcttttt cttcaggcat
    14581 tctaaatctt atgaaatttt tatcaagtcc agtaaaatca cttccagata taactcttat
    14641 ttttaattta gcaaactctt gttgtaaatc tatgtccttg tttttatgtt caactgtcat
    14701 aattgataca gtatcactag tttcagctat attaaggttt ttccatggaa ttaataattg
    14761 attttttata tcttttgttt tttcttttaa ttcttctata aattgaacat catctaataa
    14821 atttgctgca atactacgag atatttcaga cacttcgtaa ggagtagaaa tctttttaat
    14881 agggctaaca agttgttctg gaagaactgc atatcctgct cttagtcctg ctaaaccaaa
    14941 tccttttgaa aatgttttta aagcaattac attatcataa ttatttagaa gcttgacagc
    15001 tgaattttct tttggcatgt attcaccata agcttcatct accataactg ctatatcata
    15061 tttagctgct tcctttacta tattttcaat tgatgataaa ggtataattt gtccagtagg
    15121 attgtttgga ttgtctatgt aaattacttt atattctgga tttatttttt caataaattc
    15181 tttttcatta aacttgaaat tatcctcttt ctttaaaaga acataatcat aagttgcacc
    15241 atgcattttt atatctgtct catattctga gaactgaggt gaatatccta aaactttatc
    15301 tcccttttca ataaatagtc tatttaaaag gtaaataaca tgtatagaac catctgccaa
    15361 acaaattctg tcagtatcta atgctataaa atctttccaa taatcaacta tattatcttt
    15421 taaagcaatt gaatgaggat atcctcttat catatcaaat tttaaagcat taaaagcttc
    15481 tacagctttg tttgagtaag acacggtatt tataccttca ccacagtcta tctcgaatac
    15541 atcttctgaa tgtccagatt ctattgcgta actttttttc aactgcattt caatagcttt
    15601 gttaattttt agtttcatac tttatcactc cttatttagt caataataaa tgttataaaa
    15661 gttgctagat ttaaaatatt atgaaaatat ataatagtaa aaaatgaata taaatattat
    15721 aatagctcac tttatttaat atgattatat atcatatatt gtaaaatttc tagcattata
    15781 agactataaa ttgaaaatat tcagaaaaat actacaagaa acgatttatt ttgctcttaa
    15841 aataagttaa atgaatgtta ttaattttgt aaattgaaat agtttaagta taaagttatg
    15901 atataatcta ataagggtaa ttctttagat tatattaagg aaatataggt atacaataaa
    15961 aagttatgga gttggattat gggatataaa ttaattgtaa cagatatgga tggaacttta
    16021 ttaggcaata atcataaagt tacagatgaa aataaaactg cactacaaaa agttataaaa
    16081 agcggtatta atgtaacttt agcaacagga agagccttcg attcagctaa atgcaatgta
    16141 gattttctta aagaggacat gccaataata gcttgtaatg gttcattaat aagagagcaa
    16201 aatggaaaca taatatattc aaataagatt gatacaagaa catgtttaaa cattttagat
    16261 gtattagata aatacgatat ttactaccaa tgtaatagta tagattctat gctttcgaaa
    16321 aaaatagaag gacgtgaaga tagattaagt gtatttttag gctctgaaac agaagtaatt
    16381 gtaaaagatg atttgagaga agaaatcttt aaaaaagata tactaaaatt tgtaatcata
    16441 gaagaaaaaa atccatctat tttggatgaa ataagaaaag aattgagaaa agttcaagga
    16501 ataaagataa cttcttcatg gccaaacaat attgaagtca tgaatgaagg tgttgataaa
    16561 ggtaatgcag ttaaaatttt agctgaaaaa atgaatatag acagagaaga tataattgca
    16621 tttggagaca attacaatga catagaaatg ataaagtttg ctggtcttgg ggtagctatg
    16681 ggaaatgcag aagaattgat taaacaagaa gctgattatg ttacagatac aaatcaagac
    16741 agtggagttg caaaggcaat ttataaattc ctagagttaa aagaatcact tagctcttaa
    16801 aacagtatat aataggaaaa aataggttga ctattttgta gatagtaatt ataatacaaa
    16861 tagataaaac ataaaaattt agattcagtg aaaaagagag tagatataga gaaaatctca
    16921 gcgaattggg ggatggtgtg agcctaatga taacacttta tattgaaaag aactttggag
    16981 aatactactt gaaattcagt atggtagtag gtaatctcgc cttaagagaa tagagtgggt
    17041 aaacattgtt taccaactag agtggtaaca cggaatattt cgtctcttgg tctttttgac
    17101 caagagattt tttagtttca ttgagttaca agacttataa ttaaaataca aaaaattaaa
    17161 atatgaggtg aaagttatga aattatgggg cggacgcttt agaaaagcgg aaaatcaact
    17221 tatggaagaa tttaataaat cttttggcta tgattgtgta ctgtacaaaa aagatatcga
    17281 aggaagtgta gcacatgttc atatgcaagt aaaatgtgga cttttaacag aagaagaagg
    17341 aaagtctata acagaaggtt taaaagggat acttgaagat gtagaaaatg gaaagttagt
    17401 attggatgga gagtatgaag atatacatag ttttactgag ataaatttaa ttcaaagaat
    17461 tggagatgtt ggcaagaagc ttcatacagc acgtagtaga aatgaccaag ttgcagttga
    17521 tatgagattg tatgctaaag aaaaagcaaa tgatttggtg ggtttaatat ctgaatttaa
    17581 agctactata aaagatgttg ctgacaaaaa cccagtgatg atgccgggct atactcatct
    17641 tcaaagggca caagtagtga catttaagca tcacttaatg gcatattata gtatgtttga
    17701 tagagatgag aaaagaataa aaaatgctat agaaatatta gatgaatcac ctttaggctg
    17761 tggagcttta gcaggaacta cgcatgatat agatagaagt ataacttgtg aacaattagg
    17821 atttaaaaaa gtagtagata attttatgga tggagtaagt gatagagatt atttactaga
    17881 gctaatgagt gatttttcaa ttataatgat gcacttaagt agattaagtg aagagttgat
    17941 actttggagt tctcaagaat ttggatttgt tgagatagat gatttatata caactggaag
    18001 tagtataatg cctcagaaga aaaatccaga tggtgcagag cttataagag gtaagactgg
    18061 tagagtatat ggaaacttat ttggtctttt tacagtaatg aaaggaatac cattagcata
    18121 taataaagac atgcaagaag ataaagaagg ttttttcgat agtgtacata ctcttgaaat
    18181 gtgtatacaa ataatggata gaatgatagc cacactaaag gtaaatgagg ataaaatgaa
    18241 acaagcagta aaaaatggtt ttttaaatgc aacagaagtt gcggattatt tggttaaaaa
    18301 taatgttgct tttagagatg cacatggtat agtaggaagt atcgttatat attgtgaaga
    18361 taataaaaaa gcaatagaag atttaacatt agaagaatta caaaagtttt cagatgcttt
    18421 taaggaagat atttatgatt ttatcgacta tgagagtata ttaaataagg gaataaaaaa
    18481 gaatttaaaa taatgtattt atttttaaaa gctgtaaatt tgaatgttat catttaaatt
    18541 tacagctttt tattgtgtaa gattttatta tataaaagta agaaacttaa aaggagtagt
    18601 atttaaaata aatacaaata aaaaattatt attaaaatga taattaatat caataagtat
    18661 tgacaaaatt atttctaaat actattatat ataatataaa taataatgaa aatcaatatc
    18721 aaataaatgg gaggaaatct aatgaactta ttagtgattg gtggtcatga aagaatggaa
    18781 aaagattata tggttatggc caagaaaaaa ggttataaga caaaggtata tactaccatg
    18841 tcatctaaat taaataattc tataggaaga ccagatgcag ttgtcatact tacatcaact
    18901 gtttcacata agatgtctag aacggttgag tctcaagcta aaaaacaaga tatattaatc
    18961 gtaaggcata aaaatagtag taaggtagca tttaatgaat gtctagatat ggttgatgaa
    19021 tgtctgggaa attgttcaaa atgtaagctt aaagacaaac aaaaacaaaa aaatatatag
    19081 gtataaaaaa tacataaaca taaaattaaa agtactgaga taatagttat aattattatc
    19141 tcagtacttt tagatttata aggataagta tagtataaat tttttattat aatttccaac
    19201 tacttgttac tttttcatat tttttttact tctagctttt tttctttttt tcttctttat
    19261 atttgaagct attataaata aaactaaaag cactagaata cctgcaataa tcttaacaaa
    19321 agtcattaaa acattatttt cagtcaaaaa tggaagactg ctatcaagat tattttttgc
    19381 aattaagtct atactgtttt ctagtttacc attattatat acatttaaag taccaacctt
    19441 agcccctttt tttataggca aatcaatttt atttaactct gttttggtat cataattgcc
    19501 ttgagattca tctttttcta agaatatcct ataactattt tttggttcat aaatcaattc
    19561 atgttgtttt gtaaacaata cttttttagt atctgtgtat ttttctttat caacaatagt
    19621 agcacactta aagttatcaa atccataatc aatcagaata cgtgagtcta aatataaatc
    19681 agcattagtt gaattaaata cagcaacgat aactcttctg ccatctttta cagcactcga
    19741 taaaagacat ttaccagcag catcagtata tccagttttt ataccatcaa ctatatcata
    19801 ttttatattt ataggttgac ctttgtatgt aatcttatca tgtgatgtca aaaacttatt
    19861 agtgtttaca aagtatctct cataaggata tgcttttgta gcttcaaatt taagtgactt
    19921 agtttttaca atttgtctaa aagtatcatt attcatagct tctctagcta tgagagccat
    19981 atcatgagct gttgtgtagt gatttgggtc tggtaatcca tgaggattat taaaatgagt
    20041 attagtagct ccaatttttt ttgcctcaga gttcataagg tcaataaatt tttgtacatt
    20101 gccaccacca acatatctag ctaatacaaa agcagcatca ttagcagaat gaaccaaaag
    20161 agcatctagt aactgcttta cagtaaaaga ttccccattt tttagataca tactagaacc
    20221 atctatttga ggtaaatctt taatttctat tacttgattt aaatctttaa cctcctttag
    20281 aactaaacaa gctgtccata ctttagttgt tgaagctgga taaagcttag aatttccatc
    20341 cttattatat agtattttgc cagactcata gtccattaaa actgcatgtt tagcaactat
    20401 agctggttca ttatctgcaa aagagatatt agagcttcct aaaaatgaag taaatatcaa
    20461 taaacagatt aataaaagtg ataaatttct tttcattgtg agcctccaaa ttttaaattc
    20521 atcttttagt atagcatata tttgtcaata attaaaagaa aggagtgatt aatatatgaa
    20581 aaaaaaggta aaatttattt cgttttttgt tttatttatt ttaataatat catcaataat
    20641 cgtttataaa tcgcttattt tcaaagatga tatttatgtt gtaagtaaaa aaaatttacc
    20701 taatgaaaaa acacatgttg tagagaatga aattaaaggt gaagataata atcacagtaa
    20761 agtaactaaa gacatagata aaaattttca aaataataaa ataactatat acataagtgg
    20821 agcagtaaat agacctggaa ttgtaactat agagtcagac aagagacttt atgatgctgt
    20881 agaattacta ggaggaacga caaaagaagc agatttaaat ggagtcaatc tatcagtaag
    20941 attagaagat gaacaacatt acataatacc taaaataggt gaagcaacat ctgttacaag
    21001 taatgatgat tccaataaac caaatcagaa gaatgagtca agaggtgagc ctaaaaataa
    21061 atccaataaa aatatatcta acgaatcaaa agtaaatata aatgtagcga ctatagaaga
    21121 gttggattct ctacctgggg ttggagaagc tacagccaat aaaattttac aacacagaga
    21181 agaaaatgga cagtttagtt caattgagga aataaaaaat gtaaatggta ttggagataa
    21241 aaagtatgaa aatataaaag atttaatttg tgtagactaa aatataatac aaaacttaca
    21301 tatagatatg ttattataaa tatgtatgta tatgtgtgta catgtggaaa tttagtaaag
    21361 gaggcacttt tatgaaaaaa gaacaaaaaa aacttacaga gatgacaaca gcaggtggtt
    21421 gagccgctaa aatagggcca gaggttctgg catcagtttt atctcaattg cctaaaaatg
    21481 ataatataga aaatttatta gtaggactag atacagcaga tgatgctgca gtttataaat
    21541 taaatgatga tatggcactt atccaaactt tagacttctt tacaccaatg gtagatgacc
    21601 catacgtatt tggtcaaatt gctgcatcaa attcactatc agatgtatat gctatgggag
    21661 gcaaaccttt ggttgctatg aatattgttt gttttccatc atgccatgat atggatgtac
    21721 ttgcagaaat attaaaaggt gggtttgata aagtgaaaga aagtggagca cttttggttg
    21781 gagggcatac tgtagatgac aaagagccta aatatggtct ttcagtttct gggattgtaa
    21841 gtccaaataa agttttatca aatgctactg caaaacctgg tgataagtta attataacaa
    21901 aaccaattgg agtgggtgta ttaaatacag ccatgaaaga aggtatggta gaacaacata
    21961 tagcagataa agtaatagaa ataatgatac atttaaataa atatgcagca atgagttttg
    22021 agaaatttga tgtaaattcg gttacagata taactggttt tggtctactt ggtcatactt
    22081 tagaaatggc caaagcttct gaagtaagta ttgaaattga atcaaaacat gtaccaatta
    22141 ttgaaggtgc aatagaaatg gcacaaatgg gaattatacc tgctggtatg tataaaaata
    22201 tgcattatgt atctaaagat gtagaagttg taggaaatat agaagttgca gttcaagata
    22261 ttttatacga cccacaaaca tcaggagggt tgttaatttc agtaaaagaa gaacttgcag
    22321 aggagcttgt aaaagatatg aaattaaatg gagcaataga agctaaaatt ataggttctg
    22381 tagttccaaa aggggaaaaa tatattacag ttttataaaa tattatagag aaagagtgat
    22441 tgttttgagc aaaagagaat tgtttgcaat gttgccttca gttgatgaag tattaagtga
    22501 taatagaatt gtagaaataa taaatgaata tcctagaagt ttagttttag aatctgtgag
    22561 agaagtaata gatttaaaaa gacaatttat attaagatta aaagaagatg catcaaactc
    22621 tgtaacaata gagtttggtg aaataataga atctgcaata gagagagtta agttaaatta
    22681 ctcattatct ttaaaaaaag ttataaatgc aactggtaca gttattcata caaatttagg
    22741 aaggtcttta cttagtgaag atataaaaga tgaattatgg tgtgctgctt caaggtattc
    22801 aaacttagaa tacgatttgg ataatggaga aagaggttca agatactctc atttaactag
    22861 tacaataaaa agacttactg gagcagaaga tgtactagtt gtaaataata atgcagcggc
    22921 agtacttctt gtacttagca caatggctaa aggaggagaa gcaattgtat ctcgtggaga
    22981 attagttgaa gtaggtggtt catttaggat tccaagtata atggctctta gtggtgcaga
    23041 attagttgaa gttggttcaa ctaataaaac tcatttgaaa gattacaagg aggccattac
    23101 agaagataca aatgtattga tgaaggttca tacaagtaat tatagaataa tgggattcac
    23161 agagagtgtt tctatagaag aattggttaa tttaggtaaa aaatataaac tacctgtaat
    23221 agaagactta ggaagtggag tttttataga tttatcaaaa tatggtttat cttatgaacc
    23281 aactgtattg gattctattc gacaaggtgc agatgtagta acttttagtg gagataagat
    23341 gcttggaggt ccacaagcag gtattatagt tgggaaaaaa gagtatatag aaaaaatgaa
    23401 gaaaaatcaa cttactagag cacttagagt tgataagctt acaatatgtg ctcttgaagc
    23461 aacattgaga atgtatttag atgagacaaa agctatagaa aatataccta ctttaaaaat
    23521 gttgacatat aaaattgaag aattagaagt aaaagcaaat aaactatttg aaaaaataac
    23581 tgctttaaac ttaaatgcaa acataaatat agaagatgga ttttcacagg tgggaggagg
    23641 gtctatgcct cttgaaacta taagtacaaa ggtaatatca ataactcctg aacatatgaa
    23701 tgtttcatct ttagaaaaaa aactaagact tagtgaagca catataatag ccagagtgta
    23761 tgataataaa tatgtactag atgtaagaac tatatttgat gatgaatttg atgtaatagt
    23821 tgaggaattg agaaaagcat ttaattaaat aaatttgagt taataaatat taaatttaga
    23881 agtataagta tgaagttttg attaaaaaat agctacacac acttgtgact ttagtcatag
    23941 caggtttaga gggggcaaaa aatgaaaaat gtagtaattg gaacagcagg tcatattgac
    24001 cacggaaaaa ctactcttat aaaagcattg actggaagag agactgatac gttagatgaa
    24061 gaaaaaaaga gaggtatttc aataaactta ggatttactt attttgattt accaaacaat
    24121 agaagagctg gaattgttga tgtcccagga cacgaaaaat ttataaaaaa catgttagct
    24181 ggagcatcag gaattgatat agttttactt gttgtagcag cagatgaagg ggttatgcca
    24241 cagacagttg agcatttaga tattctaagc tttttaaata tcaaaaatgg aatagtggtt
    24301 ctaactaagt ctgatactgt agatgatgaa tttagagagc tagtaaaaga agatatttgt
    24361 gaaaaaataa aaggaacttt tcttgaagat gctgaaataa ttgaagttga ttctatatct
    24421 aaaagaggta tagacactct tattgaaaaa atagataaaa tgagtgatga tatagaagat
    24481 aaaaatgaaa actctccagc aagacttaat atagacagag tattttcaat aaaagggttt
    24541 ggtactgtaa taacaggcac tttaatagaa ggaaagataa gtatagaaga tgatttggtt
    24601 atatatccac aggtattaaa aacaaaaata agaagtatac aagttcatgg agaaaataaa
    24661 gatacagctt atgcaggtca aagaacagca atcaatatat caaatgtaaa agtggatgat
    24721 ataaaaagag gagatgtttt agctgcacca aactcattgg aggaatcaat gatgttagat
    24781 gtaaaattat cattggtaaa tcatttagat aaaggattaa agcactggga tagattaaga
    24841 ttgtatcatg gaactagaga gatactttgt agagcagttc cactagataa agaattaatt
    24901 gaaagtggag aaagtggcta tgttcagttg agacttgaag aaagcatagt atctaagaaa
    24961 ggtgatacgt ttgtagtgag acgttattct ccaatggaaa ctataggtgg aggtgtaata
    25021 attgacccat ctcctaaaaa acataagaaa tttgatgaaa aagttataga agcattaaaa
    25081 ataaaagaaa aaggcgaact aaaagatata atagaagagt acttaaaaag gaatttaaaa
    25141 aattatccaa atataaaaga aataatgagc tatagtggtg ctcatgaaga agatgtaaaa
    25201 agagcgcttg aaacacttat atcagaagat aaagtattta ttataggaaa tatgtatatg
    25261 catataaatc aatacaataa attaaaagaa aatacaataa agcttttaag tgagtaccat
    25321 aagaagtata ggcttagaaa agggatacta aaagaagaag taaggtctaa gatagagagt
    25381 aattttaaga ctagggagat ggatatttta ttagaaaaat tgtctacaga aaatgctata
    25441 aaaatagaaa ataatatagt atctctatta gattttgagg ttattttaaa tgataagcaa
    25501 aaagaaatag caaaaaaaat agaaaaaaga ttaaaatcat gtggagtttc ttctatactg
    25561 acaatagatg aagtttctga aggaaatcat aactatgctg aagtattgga gtcaatgata
    25621 ggtaataaag tagagaaatt agatgatttg tatataatgg acaaagatat ttatgaaaat
    25681 gcaaagaaca ttttgataaa ttatataaaa gaaaataaag aaataacatt aggagaatac
    25741 agagatttga ttgattctag cagaaagaat tgcatgatta tattggaaaa cttcgataga
    25801 aacaaaataa ctaaaagagt agaaaacaaa agaattttgt tttagtagaa aatgtctgtt
    25861 tttgctttaa ggtataaaga aggaattata atgtcgagta tcgtataatt aattagtata
    25921 aaatattaat taagaggaag tgtaaagtat tgaagaatat aatacctgat gtaaaaccag
    25981 atataaaaga aagagaagac atgagccttt tatttataat aatgggctca gtacttttat
    26041 tatttattat aaaagatata gagaaatatg aaactttatt acatgccata tatacgatat
    26101 ttttagtagc tacaggagta attatattta atactacaaa atttaaagta gattcatttt
    26161 ctacattttt aggattaatt tttatagcta ctggagtatt ggagtgtata tatttattta
    26221 attccttggg gattaaaact aagtctataa tggagattaa catcacaata tcagcaataa
    26281 cagatttatt tcctatactg ggtgtatact taagttttaa atttgttaag gataacaaac
    26341 aaatttattc aagtgtaatt ttatttatag caactgctac attaacaata acatctttat
    26401 tcataatatc aggaatttgt gactatctgg gaaatggtaa atcacaatat gctttaggag
    26461 ttataatatc tatattcata ataattattt ctatcgttag tggaattgaa ttaaattcaa
    26521 gttcaaataa aggtaaatgg gaatatgatg aaaaaaagat ttttaacaga ataatagtaa
    26581 taataatctt atcaagagtt ccaaatctat tgcatatagt tattgataat agaaatgtag
    26641 agaggatatt atcacaaata ataataaatg tagccttata ttatttatat aattacatag
    26701 tatctaagaa tattaagaaa acagcactgg aattgcatga tacgaatgaa gaattaacaa
    26761 aaaaaacgga aagtttaaaa gaaaagaata aaaaattaat ctatgagaca gaaaagatag
    26821 aggaacttaa gggaatactt atgaaaagag aatctaggct acaatctaca ttagatgtag
    26881 cagtaaatag catagtagta tttagcaaag atggagaaat tacatatgca aataagagct
    26941 ttagaaatac ttttggagac tataaagaac aagataaatt gactgataaa ataaaaaact
    27001 tcaatgattt gatagaaagc attcattatg tgtttgttca tgagaagaat gcagagaaac
    27061 ttattagtac aagcgataat aaagtttatc aagctatatt tgcaccttta attattgctt
    27121 cacaaacaga aggagtattg tgtgtactag aagataagac taagaaaaag gagtacgaac
    27181 gcaaacttat tgaagcaaat aagagaagta aagatttttt agaaagtatt ggagatggca
    27241 tagtagtgct tgaaggtaat aacaaaatat atgttaataa tgcatgtagg gaaattttta
    27301 aaaataattt agagagtatt gatttttcat tagtatgtaa aagtgaagaa agtatagaaa
    27361 aaagatatgt aatagatggt gaagtaaagt atgtagagat gagtttttct cagtatacta
    27421 atgctggtac taataaaact attattgtaa tacgtgatac aacctctcga aaaatatctc
    27481 aaataaaact tgaggaaagt caatcatcat attcaagatt tatagatata ttacctgatg
    27541 gcatatgctt attaaaagaa gatttaagta taaactatgc aaataagtcg tttttagata
    27601 tgctagcttt tacaaacata gatgatataa aagattctaa tattaaacta ttaatgaatg
    27661 cgaatactga agaaaaaatg aaatttacgg ataatatggc taaagtttta aatgaaaata
    27721 gaagtatact tttactggaa tatgaattga taaatagtta tgatgatata gtagaagtag
    27781 aattaagtgc attacctttt gctatataca atactagata cataatgctt attataaaag
    27841 atttagtaca taagaaatat tccgagcaag cagaaaaaga actgcttgaa agatttaaaa
    27901 cagataaaat caaaacggag ttttttgcaa atatgtctca tgaactaaaa actccactaa
    27961 atgttatatc tagttcaaat caactggtag attctttcta tagaaatgaa aagataaaag
    28021 attacaataa caatattaaa tctcatgtgg atttagttag acaaagttct tataggcttc
    28081 aaagattaat aaataacatt atagatttaa caaagatgga gtctgggttc tatacactaa
    28141 aacttgcgaa atacaatatt gtatctgtaa tagaagactt atttatgaat atagaagagt
    28201 atgcacttag aaaagacata aaaattcttt ttgatacaga ccttgaagaa attaatgttt
    28261 atatagacaa ggttgaaatt gagagaatta tgttgaatct attgtcaaac tgtattaagt
    28321 ttactgataa tggaggctgg atatatgtaa gtattcatta taaaatagat aaagtaatca
    28381 taagtgtaaa agacactgga gttggaatac cacaagataa attagagttg atttttgaag
    28441 aattttcaca agttgataag actttatcca gaaatactga aggaagtgga atagggcttg
    28501 ctatagttaa gaatctagta agtcttcatg gtggagatat agaagtagta agtgaagtga
    28561 ataaaggcac agagttctta atttcacttc caatgaaggg atttagtagt gaacattaca
    28621 cagaagataa gagaatatat aatattcaag aaaaaataaa aatagaattt tctgatatat
    28681 attattaaaa atgattatga gcaaaaataa aataaaaata ctatttgttt aaatatttaa
    28741 gttgtaagaa ataggctatc ataaggtaaa ttattatgat agcctatttt tagctaggtt
    28801 ttatatctat atgtgagaac atataatctc taaattacct tcaaaactaa aatctccaaa
    28861 gtcgtttggt agtataaaat gcataccctt ttttaaattg tattctacag aattgtgtat
    28921 aagttttcca tttccatcca acacactgta taaagaaaaa ggtgtattgt gtgtaaaatt
    28981 acattttcca aaaacatcta atttataaac actaaaaaat tcgtttgaca caaatgttgt
    29041 gcatttaaag tctgatgttg atacgatttt atagtcagta tcgaaattta tatgaggaac
    29101 attcgtaaca tctattgatt tttgaacatg aagttcacgc ttattacctg aattgtcagt
    29161 tctatcataa tcatagactc tataagtagt atctgagttt tgttgagttt ctaaaatcaa
    29221 tgttcctttg catatagcat gtatagtgcc acttggaaca tagaaaaagt ctcccttttt
    29281 tatattaacc tttctaagta gtttgtccca ttcattatta tttaccatat ttacaaattc
    29341 tttatgagat tttgcattat gacctattat aatttctgca tcatcagaac aatctattac
    29401 ataccaacac tctgtcttac ctaactctcc attttcattt tttttagcat attcatcatt
    29461 tggatgaact tgaactgata aattatcatt tgcatccaat atttttgtaa gtaaaggaaa
    29521 cttatcacca ggtgtgtttc caaataattc tctattttta ttccacaatt cagatagttt
    29581 tttaccttta tattttccat tttctattaa gcaatctcca tttttatgag agcttatagc
    29641 ccaacattca ccagttgttg gcgaatctat ttcataatta aatttatctt taagtgcagt
    29701 accaccccat attctatcca taaaaatagg ttttaaaaat aatggttcca taatcctgtt
    29761 cctcctatga tattaaattt atcctacaaa taattatata taaatagatt ataaaatcaa
    29821 tagtaaaaaa gttttgtccc ttgaaatgac ataaagtata aggagttatt aaataagata
    29881 aactatgata tataatataa agttctaaat tggagtgata attatggagt tgtttaaggc
    29941 agaaagcaaa aaatataaaa aagaattttt aaaattattg gagcaatggg ttagtatacc
    30001 ttcattttat gatagaaaaa ctgtatctaa agacatgcct tttggaaaag gagtatatga
    30061 tgcattaaac tggtttgaaa atctaggtag agaaaacaat ttcaaagtaa aaaatataga
    30121 taatcatgct gttcaaattg aatatggaaa tggtaaagag tatgtagata tatttggaca
    30181 ttgtgatgtt gtaaatccag gtgaaggatg ggatagtgaa ccatttaaac taaatattat
    30241 aggtgataaa ttagttgcta gaggtgtatc tgataataaa gggcctatga tagtgaattt
    30301 tttagcacta aaaatgataa aggatttaga tattaattta aaaagaaagg ttagattaat
    30361 agctggggga aatgaagaga gtggatttaa atgtataaag cattattata gcaaagagcc
    30421 atatggtgta tgtggattta ctccagatgc taaatttcct gtattaaatg gagaaaaagg
    30481 tggagcaata ataaagttaa tttcaaatat agacgataaa tctttatata taagtggtgg
    30541 aatagagttt aatacaatac cagataaagt ttatataaag aatgtagaaa aattgggtaa
    30601 agataatata tgttttgata ttaacaatat atcgataaat tatgataatg gcaattatat
    30661 tgtgtatgga aaaggtggtc attcatctaa acccgaaaaa tcaataaatc ctatattagc
    30721 tacaattaaa cttttgtcag aaaatattga tgaaaaatgg acaaaagatt tatataagtt
    30781 gataaatcaa gataatataa atggaaactt atttggttta aatattgagg ggaaatgtgg
    30841 aattttatca atggtgccaa caataataaa tatagtagat ggaaaattag aagtagtttt
    30901 aagcgttaga tatccagaaa tattaaccat tgaagatata ataaaaaaat ttaatttgta
    30961 tatggagcaa aataatatta ataaatttga gcttattggg gaaaatttaa agcaagcaaa
    31021 ttatatagat agaaattcaa aacttgtaag aagtttgcat gatatatata taaagtattc
    31081 tggagattta aaaaatgatg ttagagtaac tagtgcagga agttatgctt ctgaaatgaa
    31141 taattcagta atatttggtt gtgaatttcc tgatggtagc tttggcaatg tccatagtgc
    31201 gaatgaattt gctagcttag atagatttat aactgcaata ggtatatatg cagaggcaat
    31261 aattacatta tgtaataaaa tataaataca aaatgtccct tatatagaca tattatatat
    31321 acaattaaaa ttttacttga tatataattg aaatcaaaga gaaggtgata caatgataac
    31381 taagaaacat gcaataatag taaagagttt aagcaataaa gatggatata tgacatcaaa
    31441 cgaattagct atcaaattgg atgtgtctac taaaactatt aaaagatata tagcagattt
    31501 aaatagtgtt ttaagcaaat atgatttggt aatagcttct tctagaggta taggatacaa
    31561 gttaagcggt tctaaaaaca atatagccag agctgttaaa gaagcaaata aatatattga
    31621 tggtttttta gatgactctg aagagtcaag aatgtcaaat ataatatgta tgcttattaa
    31681 tagaaattat atgagtatag aagcaatggc agaagaatta aatctaagta tagccgctat
    31741 aaataaattg tctagtaagc ttaaaagaaa acttgaaaag tatgacttag ttataaaatc
    31801 taaaccttac tatggaagct atatacatgg tgaagaaatt aatataaggc aattaattac
    31861 tgactatgca ataaaattag atgaaaaaag taaagtgaag gtgtttttag atgacattag
    31921 tgaaaacgat atacactgta tagaaagtat tttagaaaag cacttaagag aaaaagatac
    31981 aataatttca gataaagatt ttaatctttt gctttcaaaa ataatcgttt ctgtatttag
    32041 gagtaagaga ggtcatagta acaatataaa cttaatggat acaagttata gatttcataa
    32101 ctactacttt atagaaaatc taatgaaaga aatatctgat aaaattggat ttaaacttat
    32161 tgaagatgaa gtaatttata tttcaaatta ttctggtgta atagcctata aaggtacaca
    32221 aggaagaaaa aacacaagtg aaattgagga acgaataagt actgttataa gtagtgcact
    32281 tcaagatata ttccttattt caggtagtga ttatacaaaa gatgatgagt ttatggttgc
    32341 aatctctgac catataaaga gatttttaaa tagagctaga gctaatgtaa aatcaaataa
    32401 tcctttactt catcaaataa aagagaagtt tcctatagct tttaatttag ccgtgttttt
    32461 atcaaataaa ctagaaactg agtttaattt aaaacttgat gaagatgagc ttggatatat
    32521 agctatccac tttgctgctt caaatgaaag aatgaaaaaa aatactagta agaaaatttg
    32581 tatagtttgt cattatggga taggaacagg acaacttatt tctgaaaagc taaaacagaa
    32641 tataagtgat ttaagtgttg tgggtgttta tccagttaga tatctcgata tggctataag
    32701 tcaagatgtt gatttgatag tatctaccgt tgaattaaaa ggatatgaaa aacctgtctt
    32761 atatatagaa aatatatttg atgatagctt aattgaaaac gtaaacaaag ccttttatga
    32821 aaaggaagaa agaagaaaga taataagcaa catgtttgat gaaaaagctt ttttcagtat
    32881 aaaggctaat actaaagaag aggtcataat ttcactttca aataaactaa aagaaagaga
    32941 ttttatagag gaaagttcta taaaaagtat aatagataga gaaaatattt catcaactga
    33001 aataggaaat ctagtagcaa taccccacac aatagtgaag ggagataaaa aatctataat
    33061 aggagttgga atacttgaaa atccaataat ttgggataag caagaggttc agctagtatt
    33121 tatggtattt tttaatacta aagaaaaaca taatttctcg atatttaaat acctttataa
    33181 ttttataaaa gatgaaggcg gagtaagagg aattattaaa atatgtgact ttaataaatt
    33241 aatggcactg ataggtaatt aaggaggaaa ttaataatgg gaacaaacat atttaacaaa
    33301 gaatatgtat ttttaaatgt tgatgctaag tcaaaggttg aagttttaaa atttatatca
    33361 aaaaaagcta aagacttaaa cttggcagaa gatgagagct tagtatatga aggtttaatg
    33421 gctagagaag aacaatttac tacaaattta ggagaatcta tagcaatacc tcacactaaa
    33481 aatgatgcaa ttgaaaatcc agcagtagta gtattgaagt ttaatgaaga tgttgtttgg
    33541 aatgaaggtg aggataaggt taaattagca ataagcttac ttatgccagg aaaaagtaaa
    33601 gagaatattc atcttaaatt attatcatct ctttcaagaa aattaataaa taaagaattt
    33661 aaagattctc ttttaaaaag tgataatgtt gaagaaatat ctaacttaat aaatgaagct
    33721 ttaggtttat aattaaacac taaggttata aaataaaaaa ataattaact aaaaatagga
    33781 ggaatttgaa atgaataaaa aattagtagc attatgtgct tgtccaatgg gactagctca
    33841 cactttcatg gcagcagaag caatagagca agcagcaaag gcattaggtt atgaagcaaa
    33901 agttgaaact caaggtgctg atggtgtaca aaatgagtta acaagagatg atatattagg
    33961 agcaactatg ataatacatg cagtagcaat aacaccagaa ggtatggaaa gatttgatgg
    34021 ttgtgaagtt tatgaagttg aattacaaga agctataaaa aatgcagaag gtgttataaa
    34081 agaaatagaa gaagatttag gaatataata aatttattgt ggaggaaata gaatggcaat
    34141 taagaaaaaa gttataaaca gttcaggtgc ttctacaaca ggaggaaata atgtaggaaa
    34201 atctactcca tctagtccaa ctcaatcaaa gggaaatgga aaatggaaag aaataagtaa
    34261 acatataatg acaggtatat catatatgat accagtttta gtaatgggtg gacttatagg
    34321 ggccttatct caattaatac catatgctat attaggactt gacccatctg taggtatagt
    34381 tgatgctatg aactcaggag aatttacagg gttcaagctt agtcttttaa atatagcaca
    34441 attaatgtca aatttcggat ttactttgtt tggatttgcg ataccactgt ttgcagcatt
    34501 ttgtgcaaac tctataggtg gaaaaacagc tttaattgca ggatttatag gtggatatat
    34561 agctaataaa cctgtaggtg taccacaatt cgttgatgga caatggactg aagttgttcc
    34621 agttgcatca ggatttttag gtgcaatact aatagcattt ataataggat attttgtaaa
    34681 atggttaaat aaatctataa aagtttctca taactggtta gcttttaaaa caacattttt
    34741 aataccatta atagcgtcat tagcttgtat ggtattgatg atatttataa taactccatt
    34801 tggtggatta attaatgaaa gtatgaaaaa cttcttaaca gcagcaggag cagctggaga
    34861 atatgtatat gcaacagctt tggcagcagc tacagcattc gacttaggag gaccaataaa
    34921 taaagcagca ggattcgttg cacttggttt aactacagag aatgtacttc caataacagc
    34981 aagaacaata gctatagttg ttcctccaat tggattagga ttaacaacat tattagataa
    35041 aagattagta ggaagaagag tatatgatag acaattctat caagcaggaa aaacttctat
    35101 attcttatca tttatgggta tatctgaagg agcaatacca tttgcacttg agagaccagg
    35161 ttttgttata cctttaaaca tagttggaag tgtaatagga gctattacag gtataattct
    35221 aggagcaatt caatggttcc cagagtcagc tatatgggca tggcctctag tagataactt
    35281 atttggatat ataataggta tagcagttgg tgctatattc atagcagtag gaaatatatt
    35341 ctatagaaat aaattaataa aagatggtaa acttgttgta gattatatcg actagtattt
    35401 aatttttact atctataaat aactttggct ggtaatatgg ttttaatcaa tattaccagc
    35461 cttacctata tgattaatta aaggcggtgg agataagata tggataagat agaaaaagta
    35521 agagagtatt ttagagaata tgatatagat ggatttctta taaatagtcc tacaaacaag
    35581 ttttatgttg gaaatttatt tagctcttca ggttatgttt ttataactaa agaatcacaa
    35641 tatataatag tagattttag atattttgaa gaaattaaaa gaaaatctag tttgtttaat
    35701 gtagtattaa tggacaaaac tagaactcat tttgatataa ttaatgatat ttgtagagag
    35761 cagaatataa aggaaattgg atttgaggga aatgaagtat cttttgattt atatagaagt
    35821 atgagtaata agttaagtgc aaccttaaaa tcagttgatt tatctacatt aagggaaaca
    35881 aaaaatgaag acgaaataaa atatataaaa aaagcttgtg aaatagttga tgctacattt
    35941 tatcatatag tagactttat aaaggttggt atgactgaaa agcaagttga aaatgaaatt
    36001 gttagaatta taaaagattt aggtggtcaa aaagaatctt tcgatacaat agttgcatct
    36061 gggcttagag gagcattacc tcatggaaaa gcaagtgaaa aagttataga gtatggagat
    36121 tttgttacct ttgactttgg tgctaagtat aataattatt gttcagatat taccagaacc
    36181 atttgtatgg gtactataaa taaagagtta gaagaaatat ataatatagt aagaaaagct
    36241 aatgaagagt gtataagggt tttaagaccg ggaatgacta ctggagagat agataaagtt
    36301 gcaagagaca taattggttc atatggatat gccaataatt ttggtcataa tctgggtcat
    36361 ggtgtaggaa ttatggttca tgaatatcct gcattagctc ctgaatcaaa tgaagtatta
    36421 aaagaaggaa tgattgtaac tatagagcct ggtatatatg ttccaagtct tggaggcgta
    36481 agaatagaag atgatgtact tataacacaa gatggatgta tgagattgac tacatctact
    36541 aaggatttaa tagttgtaag ctaaaaataa attagataaa tattttataa caataagaaa
    36601 agaagaggta aatttaaatg tataattttg atgataaacc agatagagta agtgaaaagt
    36661 gtagaaaatg ggatttaaat attataagag ataaatttgg agatattaga gaagatttta
    36721 taccaatgtg gattgctgat atggatttta aaataccaac agaaatagaa aacaaattta
    36781 ttgaagctgt aagaagaggt gtatttggat atacatactg ttatgatgaa ttttatgatt
    36841 cagttattgg ttggcaaaaa aatatgcatg aggtaaatgt agaaaaagaa tggattacat
    36901 taacttatgg aactgtatca acacttcatt atgtagtaca agctttttgt aagaaaggtg
    36961 atagtataat attaaataca ccagtttatg acccctttga atcatcagca aaaaaacaag
    37021 gtgtaaatgt aatttgtaat acattagatg ttgtaaatga tagatattat ataaattttg
    37081 ataaattaga agttcaaatt aaagaaaata agcctaaatt aatgatgttt tgtacaccac
    37141 ataatccatc tggaaggata tggacaattg aagaaatgac aagggtagca actatatgta
    37201 aagaaaataa tgttattttg gttgcagatg aagtacatgc agagcatatt cattatggta
    37261 catttaattc aatacttaag attggaaaag agcttttaga aaatgttatt ctattgacat
    37321 caccaaataa aggatttaat cttggtggat taaagacttc ttattcaata gttataaata
    37381 aggatataag ggacaaattt agaaataaat taaagcaaaa ttctataact tctccaaatg
    37441 tgtttggaat aataggattg ataaccgctt ataatgaatg tcatgagtgg ttaagtggtg
    37501 taaatgaata tataaaatca aattatgaac ttttagaaac ttgggtaaat aaatataata
    37561 agataaaatt gatgaaaatg gaatcatctt acttagcttg gatggatata agtggattag
    37621 gtattagtgc aagtgagttt acagataaat tggctataga tacaggagta ttattagaag
    37681 atggaagtca ttttgtaaaa gatggtgaga agtatgttag aataaattta ggaactcaaa
    37741 aggaaaatgt aattgaagcc ttaaatagaa tggatttatt tttaaagtct ttataaaaat
    37801 ttggttgaat tagtatttta tataaattta aactattaat atggtatata cataagtaga
    37861 atttgtttta gattacttaa gtatatacca tattttatat aaaaattaaa tttgcattag
    37921 tcatgtgata actatttaaa ttcatatgta ttttgtatgt ataatagata taattattat
    37981 ttaaacttat tgtttattta atttttcaat agaaaaagat ttatctgtaa gtttaaaatt
    38041 atcttttata cccttagtta agtatacttt cttatcctta gttatgaata tagcatctac
    38101 attatcaatt ttattaatta aattcatacc tttttcaaga ccaagaccaa atgtagaagt
    38161 ggataaggca tcacaattaa tagatttatc agagattatt gtaacactac ttaaattgtt
    38221 ttcaaaagga taccctgtaa atggatttaa catatgatga tatatttttc cgtctttttc
    38281 gataaatctt tcataaattc cagaagtaac aacagactta tttgtagttt ctatgtttcc
    38341 tatggattca ccatttttac tagttgggtc ttgaatacct attttaaaag gtttatcatt
    38401 tttaccattt tctaaagtaa atatatttcc tcctaagttt actaaacctt tttttacatc
    38461 ctctgatttt aaataggcta caattttatc agcagcatat cctttagcta tggcacctaa
    38521 atcaattttc atattttctt tggttaattt tatagattta tttttttcat ccaatatgat
    38581 gttcttataa tcaataagag gcagaagttt ttgtatctta gaatcacttg gaactttagc
    38641 tttatctgtt ccaatagccc ataaatttga taatggacca attgttatgt caaaatatcc
    38701 atctgataat ttggaatatt gtatagcttc ttttacgacg aaaaatgtat catcagaaac
    38761 tctgacaaat tttttaccag cattatcatt tattttagaa acatcacttc ctggtatatg
    38821 agtgctcatt ttgttgtcaa tatatcttaa aattgaatca cattcattta agattttatc
    38881 acttttggat tcttttacat taaatacagt aacttcgttt actgtaccaa ggtagtagct
    38941 agttttacta tatttagtat tctggcttga actcctaaaa aatgaaaata aaattaatgc
    39001 taaaatcaat atcacaaaaa taaatgtgat ttttttctta ttcatggtat attcctccta
    39061 tgaaattgtg ttattatttt attataacat aatttcatag gaggacaaaa aatgaagaaa
    39121 aaagacattc ttcttatttt aggcattttg gttgttatta cagcatgtta tgggataata
    39181 aatgttataa attctaaaaa tgctggaaat attgagattt atgtagataa taaattgtat
    39241 aaaactgttt caataaatgc caaagaagaa tttaaaatag agagtagagg ggggtataac
    39301 atagtaaaga ttcatgataa aggggttgag atagtagatg cttcatgccc tgataaggtt
    39361 tgcgtacata ctggatttat aaacaagcca agtcaaagca tagtttgtat acctaataga
    39421 gtgagcataa aaataaatac aaatgaaaag aatgataatc aagaagatat aatttctaaa
    39481 taaaataata aaaataattg aaaggaattg gtgataatta tggttaactt aggaaacgat
    39541 tgggatgaat tattgaaaga agaatttgaa aaagattact acttaaactt aagaaaattt
    39601 cttatagaag aatataaaac acgccaaatt ttcccaaata tgcacaatat atatgaagct
    39661 ttaaaacaca cttcatacaa agacacaaaa gtcttaatat taggacaaga cccttatcat
    39721 ggagataatc aagctcatgg tttagctttt tcagttcaac cacaagtgaa aactccacca
    39781 tctttattaa atatgtataa agaattaaaa gatgatttag gttgttttat acctaataat
    39841 ggatatttaa tgccttgggc agaccaagga gtgttacttt taaatactgc tcttactgtt
    39901 agagcgcatg aagctaattc tcataagaac aaaggatggg aaattttcac tgatagagta
    39961 atatctattt taagtgagcg tgaagaccca gttatttttg tactatgggg aagtaatgca
    40021 cgtaaaaaag tagagttgat tgatacaagt aaacattata ttttggaagc acctcatcca
    40081 agcccattgt cagcaagtaa aggctttttt ggatgtaaac acttctctaa gataaatgaa
    40141 attttgaaaa agctaggaaa agaacctatt aattggcaga tagaaaatat ataaaagtaa
    40201 aaggtaacaa aatgataaca aaacaacaat aaacaatgac attgttgtaa ctaatagaaa
    40261 tatgcttaaa tagttgaaaa tactatgtat gcatatttct atttttttgt caagttgaca
    40321 actcttgaaa aaatagttac aatttagtta cacaaaaaac acaaataaaa aaagaaactt
    40381 acaaagcaga attttatgaa gcaaaatata tagtgtaaaa aatcttaggg aggaaatttt
    40441 atatgaattt taaaaaattg agtaatgcta aagtctcggt aatggcagtt gttttatcag
    40501 ttggaatatt atcgggatac tctgcgctta ataaacaagt aacattagta gtaaggggag
    40561 aagaaagaac tatatcaaca tttagttcta atgtaggaga ccttttagaa tctcaaaaca
    40621 ttagctatga ttcaaatgat atagtaactt tagatgaaaa tacaaagtta tctaatggag
    40681 ataaaataga agtaattgat gtaaaggaaa aaacagttgt agaaactaaa gacattccat
    40741 ttgaagttac agttgttgaa gatggctctt tattaaaggg tgattctaag gttaaagaag
    40801 aaggaaagtc tggtaaaagt gaattaatat ataaagaaac ttatcacaat ggaaagaaag
    40861 tagaaaagga atttgtgaaa aaggttgtta aagctgagcc agtaaataag gttgtaagca
    40921 aagggacaaa ggtagaaatg caagtagcct catcaagggg agaaagttca agaagaatgg
    40981 cttcatcatc atctagtagc agtagtagta acaatggtaa aaatatgaga gtggtagcaa
    41041 ctgcatatac tggtcacagt ataactgcaa caggaacaaa acctaagtgg ggaacaatag
    41101 ctgtagaccc taaggttata ccatatggaa ctaaagttta tatacctcaa tttgacatgg
    41161 tgtttactgc agaagactgt ggtggagcaa taaaaggaaa taaaattgat atctacatga
    41221 atgattcaaa aacagtttat aactggggaa gaaaaactat agatatacgt atattaaaat
    41281 agttaaataa tttatatttt tactggaaat tatattttga ttatatagag aagaaactct
    41341 ttatagattc taaaaatata atttccagtt ttttattttg gatatgtaat aaaacaggta
    41401 aattttaacc atgtatagat aaaagctatt taaattataa tttactatca tataaatcta
    41461 taaaaattgt tgcaaagagt caaaatatat gatattatag atttcgttga gaaggatttc
    41521 attatgggag tggatgggtg ccggtgtgcc ctctagtctt caaaactagt atgaggggtt
    41581 aagagcctct taggtgggtt cgattcccac gcattcccgc caatatgtaa aaggtatctt
    41641 ttaattaaaa gatacctttt taaatttatt ttaagataat ttatttttaa taatatataa
    41701 tgttttgtat tatataatgt aaattttcta atactattat atatttagat aaaaatctag
    41761 gagtgtggaa agatggaaaa taattttaca acgagaacta gttttctagt tggagatgat
    41821 gggataaaaa aacttaataa ttcaaatata atagtatttg gagttggagg agttggtagt
    41881 tttactgttg aagctttagc aagagctgga gtaggcaata ttactattgt agattttgat
    41941 gatgtagata taaccaatat aaatagacaa ataccagccc tacattcaac tgtaggaaga
    42001 tacaaagttg atgtcatgga agaaagaata ttagatataa atcctaatat caatataaaa
    42061 aaaataagaa gtctttataa taaagatact agtgacgaaa tactaactga aagatatgat
    42121 tatgttgtgg atgcgataga catggtaagt tccaaaatac atctaattga aacttgtgaa
    42181 aaaaaaggat tgaaaataat aagttctatg ggtatgggaa ataaattaga cccaactaaa
    42241 atagtcgtta cagatataca caaaacaagt acttgtcctc tagctaaagt tatgaggaaa
    42301 gaacttaggg atagaggtat caaaaagtta aaagtagtat attctactga acaaccaata
    42361 gaacttaaga agaaagtaat gaatggtaga aaagtaacac ctggtagtgt atcatttgtc
    42421 ccatctgtag gaggtttaat aatcgcatct gtaatagtaa atgaactatt aggacaataa
    42481 gttttaaata ttttaattta taaattttat ataaaaattt gaaggctaga agcatgaata
    42541 caaagcaatt ttatattcat acttttagcc taattatttt atattacctt attttatgta
    42601 gttgtagttt tattttttag attatgtatc tatttcataa ttatattttg taaatataat
    42661 ttctccatca ctataaaaaa caatatctcc tattctatct gttctataaa ttgatacatg
    42721 gttttgtttt agattattaa taacctccct atgtggatga ccatattgat ttttatatcc
    42781 acatgatatt gcagctatat ctggactaat tttttttata aattctaaag atgaagaaga
    42841 attacttcca tgatgaccta tttttataaa attaatatta tttaatttaa aagaatgtaa
    42901 aatttctttt tcattttctt cttcagcatc acccataaat aaaaaagaat tatcattaaa
    42961 agttaatttg aaaactatag aatttaaatt agattcttct tgtatatatg atggacttaa
    43021 tacatatata tttatattgt tatctatgtt taaaacatca tttttataga gatgctgaat
    43081 agataagttt ttatccgtac aagaatttat tagattttga taagccttac tatcagttga
    43141 ttgttcaggc atatatatgg agtttacatt aaattttttt ataatattat caagacttcc
    43201 tatgtggtct gaatctggat gagttgctat tataatatca atagttttta ttcttttttg
    43261 tctaagataa ctaataatta tattttcgct atcttcatca cctccatcaa ttaatatatt
    43321 cttatttgtg ggtgtttgaa ctaaaatact atcaccttgt ccaacatcaa tcatatgtat
    43381 agatagtaga gattttttgt cacagccgat taaaagtgat attataataa gtattgataa
    43441 aaaaatttta tttctcaata aaaaatcact ccattcatta catgtttata taaatttatg
    43501 atgggtaata taagatatat atgacttatt atattttata ttttaaacaa tataaatgaa
    43561 attaatacca taataaaatt ggagtttttt atatatacaa aataaaattt ttaaaattaa
    43621 gcaataaaaa aggtaggagg attttatgtt tttcaaagat attgaactaa attcaaaaaa
    43681 agagttagac ccatattttg atttagtaga ttatgaagct tgtgagtact gttttagtac
    43741 tttatatatg tggcaacatg tttataagac aggatattat ataggtgaag attttgccgt
    43801 tttagttggg gaatacgaag gagatagctt ctcaatatta ccacttgcta aaaaagataa
    43861 acttccagaa gttgtagatt ttgtccttga atatttttct aaaaataata aaaaaatata
    43921 cttaagaggt attactactg aagtagtaga gtttttaaaa gaaaaatatc caggtagatt
    43981 tgagtatata gaagaaagag atttatttga ctatatttat gatgcagaaa gtttaagaac
    44041 tctagctggt aaaaagaatc aaaagaagag aaaccatata aactatttct taaaagagta
    44101 tgcaggtaga tatgaagcta aattattaga taaagaaaac tttgatgagt gtttagtact
    44161 aatgaaggaa tgggaaagta ataaggaaga aaataatgaa tttgatgaaa gtatggatga
    44221 tgaattaata ggtatcaaaa agatatttaa ccattatgac atattaaaag ataaggtaaa
    44281 agtgtttggt gtttatgtag atggaaaatt agaagctttt agtataggag agcttttaaa
    44341 tccaaatatg gcattgattc atatagaaaa agctaatccc gatataagag gtctgtatcc
    44401 atttataaat caacaatttt tggtaagtga atttaaggac gttgagtttg taaatagaga
    44461 agaagattta ggtattgaag gattaagaaa agctaaactt tcttatcatc cttgcagatt
    44521 tgttgaaaag tacagtgtta gggaggctta atagactata tggagattag gtatgctaaa
    44581 gaagaagaga tagaaagtat aaaagatatt tggagttatt gttttaacga tacggagagt
    44641 tttatgaagt actattttaa tgataaatat aaatctgaaa atactgtagt agctttagat
    44701 gaaggaaaaa ttatttcttc tcttcagcta aatcagtata agttattact aaatagcaag
    44761 gtatataata catcatatgt ggtaggagtt tctacacttc cagagggaag aggagctgga
    44821 tatatgaaca aagtaatgaa atttacttta aacgaattgt ataaaaaagg gcaattagtt
    44881 tctatattga tgcctattga ctatagactt tatagaagat ttggatatga gcattgttac
    44941 gaccagattg aatatactat taacacagat gatttaaaaa attttaagtc aagtggaaaa
    45001 atgataaagt ctaatttatc acaaattgat gatttgatac aaatagatag aactttttta
    45061 aatgaggtta atggtaatgt gttaaaagat gaacattatt atgaaaactt atttaaagag
    45121 attcaaagtg aagatggatt tttatacatt catgaaggaa atgaaaaaga tggatatata
    45181 gtttattttc ttcaggaaga taaaatgttt gtcagagagt tattttataa aaatatagat
    45241 gcccttaaat caatgcttaa atttatatat aatcacaata ctcaatgtaa gatagttact
    45301 atatctactc ctacaataga taagataagg tttatattag acaaccctaa agatagtgat
    45361 ataaaaataa aaccttttat gatgggaaga gttataaatg taaagaagtt tattgaagat
    45421 atagatattg agaaggatat taatagctca tttaatttat taatagaaga caagtttata
    45481 gatgaaaata atggtctatt taaaatttct atacagaata agaaggtatc tgtagagcag
    45541 ttagataaaa aaggtgcaga aaagcctcaa gaagattttg atattaaatt agatataaat
    45601 accttaacac agttatcatt ttcttatata gatgtaaatg aagctatttt cttaaatgat
    45661 ataaaagatg tttcagaaga aacactagaa acacttaatt gtattttttc taaaaaaaat
    45721 aactatataa atgaatatat ataggtagag tacgttaaaa gattttaaaa atcttttgac
    45781 gtattttttt gtttagataa caatttatct tgtttaaaaa ttttctattt gaaaataatc
    45841 taaataatat acttttatat gggagtgatt ataattcaaa taagaagacc attattaatt
    45901 atattaatgt ttgtggtagc tatatcattt atcattacaa ataacacaaa aaacgacgaa
    45961 gaacttaatg ataagataat aactatacaa ggagttgtca aaggaaaaat tgaaaagaaa
    46021 agatacaatc agtacaaggt aggggttttt ctaataaatg attatacaaa aaataaaaat
    46081 ttgaagattg gtcagaaagt taatattaca ggtaaattca aaagtttaga taaaatgaag
    46141 tatgatgatt ttgattatgg aaggtatata aaaagtactg gatataaagg tatagtgtat
    46201 ataaataact ataaaattat tgataaaaat aaactttact ctttaatagg ggaaataaag
    46261 ttttatatta gtaaaactta taggtactta tataagaaaa actcagattt tataaattct
    46321 atactattag cagaagttga aaatttgact gaggaacaaa aagaaatttt taccagaact
    46381 ggaactagtc atgtaatatc tatatcaggt cttcatacag gaatattatg tgtaattata
    46441 tcctttctat taagaggtat aaataaattg tataaattat taatactgtc gatttttata
    46501 actttatatt gtataatggt aggtgcgtct ccatccataa ttaggtctat agcatttgtt
    46561 atgatttttt atttatcaat atttattgat agaaagaaag atggaatatc ggcattgtct
    46621 ctaattggga taattttaat tatgaataac ccctatgtta tatataatgt aagttttcaa
    46681 ttgtcttttt tagctacact ttctatatta atattctata ataaaataaa tagtattata
    46741 aaattaagta tggtatcatt gacaatatca tcaaatatat taactttacc tataatttat
    46801 tatacattta aaggtatacc attgctttca attataggaa atttaattat agtgccattt
    46861 gtgggagtaa taatgtattt aagtattgca agtttaatcg tatttaaagt aagtgtagta
    46921 atagctaaaa ttatatcttt ttttaatagt acatttatag aaagcatatt ttttttacta
    46981 gaaaaaatca gcaatttaag ttttgcatac attaatatag aaaatcctaa attttatatt
    47041 gttgttattt attacatagg agtgtttttt tacatatttt acatagaagg aaaagagata
    47101 aaggagcaag agaatgaatt acaaggatat tataaggaat gtaaaagaga aaaactttga
    47161 aaaaatgtat cttttttatg gaagagagta ttatttaatt gagaatgcaa taaaagcatt
    47221 taaagatagt ctaaacgagg gaatgcttga ttttaattta gatataatag atgggaagga
    47281 aatagtctta aatcagctta taagctctat agaaacactt ccatttatgg atgataggaa
    47341 gatagtaata ataaaagact ttgaactatt aaaaggaaag aaaaagaatt ttacagatag
    47401 tgatgagaaa tacttaatag agcatttaga caatattcca gacaccacaa ctatagtttt
    47461 tgttgtatat ggagatgtag acaaaagaaa atcattagtt aagaaaatag gaaacaatgg
    47521 aattgttttt gattgtgata agctttctga tatggatttg tttaaatgga taaaaaaatc
    47581 ttttgcttta aatgatgtta taatagataa ttctcaaatc atgtatttta ttgaacaaga
    47641 aggatacaga gataagagta gtgaaaagac attatctgat ttagaaaatg aaataaataa
    47701 aataagttca tttgttggta aagggaataa tgtaaccaat gatgtaattg ataaattatc
    47761 tcaaaaaaaa gttgagaatg atatattcaa attaatcgat tatattggag aacaaaatgc
    47821 ttctaatgca atgaaaatat taaatgatat gatacaagaa ggcgaatctg tattaggtat
    47881 attttctatg atagcaagac aatttaaaat aattatgcaa gtaagacagt tacaacttga
    47941 tggatattca acaaaactta tagctgataa attaaaaatg catcaatttg ttgtaggaaa
    48001 agcattaaag caaactaaaa atttttctga tgatataatt gtggaaatat taaactatat
    48061 attagaaagt gattacaaaa taaagacagg tcttataaga gatactttag cagttgaaat
    48121 gttggttagt agatactgta aaagagaagc aatttaaaaa atctatatat taataaaaaa
    48181 taaatagcaa gatatgttat agttcagagt agatgtaagc taaattaagt ttgatataca
    48241 atcaactata atatgtctaa ctatttattt tttattgtat aaatttacaa aataaaaaac
    48301 ccctacatag gggttattat atataagaaa tataaactgg taattaagcg ttcataccgt
    48361 ttaatttttg agctaattta gctacttttc tagctgcagc attcttatgt atagttcctt
    48421 tagaagctac ttggtatatt cttttttgag cgtattggaa cttagcaaca gcatcctctc
    48481 tgtttccagc tgcaacagca tcttcgaatc ttcttattgc agtttttatt tgagattttc
    48541 taactctatt taaagcagtt ttcttttcga taacacttat tcttttctta gctgatttta
    48601 tatttgccac cgtgttcacc tccctgtatt tttttatcat attcatcgtc aacatattag
    48661 attttaacag aaataaatct aaaaatcaag gattattatt tatatatttt aataatgttt
    48721 tttattttga ttttttagac tgtaaattgt gtataaataa tttgcaatat cttgttttta
    48781 aattggtata ttttgtgttt taaatatttt gacatatata attaatattt cattttgtaa
    48841 caaatatttg agataataca aactattaac atacattttg atagtatttc caataattat
    48901 aagataatac aagaaattac tcatttttgt aaatttaatg aaaaattata aaaatataaa
    48961 tttatatgct taattaagat aatttttcca ataatcaaga taattttttt cattagtatg
    49021 tatgatagat gcatcaaaca atataactaa tatgttagaa ggttatatgt aattaatgtc
    49081 agtgtttata tagaatagca tttgtagcat ttattatagt tgtaattact atttatatca
    49141 tagacttgaa tagtctaaaa aaatagacta taatattttt atagactaaa gaaagggctg
    49201 ataagatgga catagcaaaa ctaattttaa atcctgcaag gcttcgtatt ttacaatata
    49261 ttcgacttta tggcagtgtt cgtacatctg atattgtaaa gtatttaaat gatattcctc
    49321 gtgcaacagt ttatcaccat gtaaaaattt tagaagagaa caatatgatt gaagtaatta
    49381 aagaaaatcg tgtgcgtggt actattgaaa aggtttatgc actaaaggaa tatacaacat
    49441 ctatggaagg agagaccttc gttgcacttt ctacagcatt ttatgtaggt ctgatgcagg
    49501 aaatgaatga atactttagc agaaaagagc aagaccataa aaaggataat gtatttttct
    49561 cttcagcatt actatatatg agtgataatg aatatgaaaa tcttcttaaa agtatagctg
    49621 atttattgaa accatatata gaacaaaaac ctaaatcaaa tctaaaactt agaaaacttt
    49681 caattatatc ttctccacct gtagctgata atgataaaac aaaataacat gcaacccatt
    49741 tttataaaag gaggttatat atgaaatttc atgagtttgg aaataaaaac agaccacata
    49801 ttatgttgat tcatggggga gggaatgcat ggtggaacta tttgcgacaa gcagaagttt
    49861 tgtctaacaa atatcatgtg atacttccta cattggatgg tcatggagaa gaatatgaaa
    49921 caacatacat ttctacagag gatacagcag ataagttgat atcatatata gatgaaaatt
    49981 gcagtggaca tcttttcgct ttgtgtgggg tatcacttgg tggtcaaatt gtcatggaac
    50041 ttttatctcg aaaacctaat attactaaaa aagcaattat tgatggtagt atttgctacc
    50101 caagacctct tatggcaagg ttttgtattg ctggtattcg attttttgga ggacttttgt
    50161 ttagtgagaa ggcttgtcgc tttcaaattg ctatgatgcc aaaattgtta cctgaaaata
    50221 tgcaatatcc agatgaaata aaagcgtatt atatgacaga tatgccacat gtaagaaaag
    50281 aaacattcta taatatgtat cgtacttaca tgatgaacta tacacttaaa gagaatgtta
    50341 aaaaaaccac agcacaagta atgtactggt atggagaaaa agaaatgaag tgtgtcaaaa
    50401 aatctgcaaa actgtttcag tcttatgtgc cctcttgtga gatttatgaa gctaagagct
    50461 ataatcatgg gtatttatca ctttatcttc caaatgaatg gttggaaatt gcagaaccat
    50521 ttttccaaaa ggaataaagg tgttaggtga ttattgtata attattgctg tttttttata
    50581 tagtaaataa attaggtata aatataaaaa attattttag ttaatatatt agtgaaagct
    50641 taataggaaa attataaata gattaaaggt agcacctata taaatagttg ctaccttttt
    50701 ctgtttgtaa ataaatgata gataagaagg tttactgaca aatcactgac taaacccaat
    50761 tttcttacat tgaaagcctt aattttactt gttttaaata aatttacaat ttcttgttat
    50821 aaaatactaa attttgttaa caattataat tagcatttaa tttatactgg aggtttatat
    50881 gattagtgta agaacagatt tagctttaga agctagtgaa atgtgtgaaa agtctcaaga
    50941 aggaagtagt attcctggtg taaaaataga aactaaagaa ttagaaaatt gcattgtaac
    51001 taaagttgaa gtaatagaca ggcaaggcgc agagataatg aataaagata taggaaagta
    51061 tataactctg gaaagtaatc ttatgaagtt tgatgatgat gagtcaagag aagaaatgat
    51121 aagttattta aaagaggagt tagtagatat atttggccaa gacaaaaata aaaaaaccct
    51181 ggtaattggt cttggaaata gaaatattac ttctgatgcg ttaggaccaa agagtgtatc
    51241 aaaaacactt gtaactagac atctttttaa aaattataat aaagactatg atgatgattt
    51301 cactgaggta tcagctttaa gcccaggagt tatgggtgtt actggaatag aaactagtga
    51361 aatagtaaaa tcattggttg agaaggttaa gccagataga gtagtagcaa tagatgcatt
    51421 ggcttcaaga aaaatggaga gagtaaactc tactatacag atatcaacag caggaatatc
    51481 acctggtgga ggtgttggca atactagaaa atctctaact aaagaaactt taggcgtgga
    51541 tgttattgca ataggcgttc caacggtggt tgatgcagca actcttacaa tagatgtctt
    51601 agatatggca atagacaatt taatagctca atcagaagaa acagaaagtt tttatgaaat
    51661 gttgaaaaaa cttaaagaag aagaaaaata tcatctaata aaagattcgt tagacccata
    51721 tgacaagaac ttaatagtaa caccaaagga tatagatgat acaatcgaaa atctatctat
    51781 aataataagt gaaggcttaa ataggtcttt acatccaggt agattggtat aaaataagga
    51841 ggagcaatta tgtttaaaaa atgcattaaa gtagtaacct tgacttttat attagtatgc
    51901 attttaccag gaaaatcatt agctttgaat caagatgatt ttttaaagtt tttagtaaat
    51961 tcatcttatc cagaagctaa agtcgaagga aatgatacag aaaataaaaa gaataataaa
    52021 aataaagaaa caagtaagga aaataaggaa gaaagtaaag aaggaaacac taaatctaaa
    52081 gatgcaagta aagttgataa taaaaaagag agtgaaaaag aatatataaa actttatgtt
    52141 ggtaaagaaa atgttccaga tattgagtca aaaaattcag acacaactga aactaacaca
    52201 acatctagtt cagattataa ggatgattta agagtaacca aagaaaatcc aagaattttg
    52261 atatatcata ctcatggatg tgagacttat tcaaattcac ctgatggaaa ttatcattca
    52321 agagataaga aaaattcagt aatggaagta ggaagtgcat taactagtgc tttagatagc
    52381 aaaggatggg gtgtagtcca tactactaaa taccatgact atccatctta taataactct
    52441 tatgcaagta gcttaaaaac aatacaaagt atattaccta aatataactc agtggatata
    52501 gcgatagact tacatagaga tgctagggat ttaactaatc cagccactaa ggaaaaagac
    52561 catttaaaat atacaactat gataaatgga gagagagtat caaagttctt ctttgttgta
    52621 ggaggtaaaa atacaaatag aaaacaactt agagctttag cagaagatat aactgctttt
    52681 gctgagaaaa agtatcctgg tctagtatct ccaatagtag aaaaagacta tgctagattc
    52741 aatcagtttg cagttaagaa tcatatgtta gtagaaatag ggaataacgc aacaagtgta
    52801 gaagaatcta aggctactac aaagtattta gccgagattt tggatgaata ttttaaacaa
    52861 aaaaattaga gctttaagtt ataattagga gcatgctaaa tgagccgatt agaaaaaaat
    52921 atagaaagta aaagtaaact aagaaaatac aagtatatta tgagaatctt atttttgatt
    52981 actatgatta tatgtacatc agtttgtgta tttatagtgg acagtaatgc aaaaagtatg
    53041 ctaggaatga aacaatatga ttttccaagt attaaatttg atataacaaa atttgatttt
    53101 gacataccaa attttgatat acatgaaatc ataaaaaaat ttaataagta gtaataagtg
    53161 aataaggttt attgattaaa ataagcctta ttttagttat atatttttaa tgtataaaat
    53221 aaaaattcat taactgtatt ttataggatt tactttaagt ttatgatatt atataatatt
    53281 tagtgttaga cttgataatc cacatataat gtggataatt ttgtttagtg ccaattagtt
    53341 tatattcaaa aattttaaat ttggtatata aagagttttt agataatgta aaataataac
    53401 tataagaata atcaagagga gggaatttta aggtggacaa taaacaaagt agaactagaa
    53461 attttagtat aattgcacat atagaccatg gaaagtctac cttagctgat agattaatac
    53521 aacaaactgg gcttgttagt gaaagagaca tgaaaagtca attacttgac aatatggacc
    53581 ttgaaagaga aagaggaatc actataaagc ttcaaaacat aagattaatg tataaagcga
    53641 aggatggaaa tgaatattat ttaaatctta tagatacacc tggacatgta gactttaact
    53701 atgaggtatc aagaagttta gctgcatgtg aaggagcact attagtagtt gatgcagctc
    53761 aaggtgttga ggcacaaact ttagccaatg tttatcttgc tatagaccaa gatttagaaa
    53821 tattaccaat aataaataaa atagatttac caagtgcaag accagaggaa gtaaaaaatg
    53881 aaatagaaga tttaataggg cttgattcaa gtgaagctcc tcttatttca gctaaaactg
    53941 gtttaaacat agaagatgtt ttagaagata ttgtaaaaaa tgttcctcca cctaaaggag
    54001 ataatgaagc tccattaaag gcattaatat ttgattctta ctatgatgct tacaaaggtg
    54061 ttgtagctta tgttagagta tttgaaggaa ctgttaaaaa gggtatgaca ataaaaatga
    54121 tgaataccaa taaaaagttt gaggtaactg aagttggtgt tatggctcca ggtcaaactg
    54181 aacttagtga attatcagca ggtgatgttg gttatattgc tgctagtata aaagatataa
    54241 gaagttgtcg tgttggtgat acaataacag attcaaataa tcctacagaa gaacctttac
    54301 caggatacaa aaaagctact ccaatggtat attgtggtat atatccagga gaaggagaaa
    54361 agtatgagaa tgttagagat gctcttgaaa agcttcaagt aaatgatgct gcacttgaat
    54421 atgaagctga gacttcagca gcactaggat ttggttttag atgtggtttc ttaggtcttt
    54481 tacatatgga gataatgcaa gaaagacttg agagagaatt taaccttgat ataattacta
    54541 cagctccatc tgttatatat agagttacaa aaatggatgg agaggttgta atgatacaaa
    54601 atcctgcaaa cttaccagaa ccatctgaga taaagatgat agaagagcct atagtaaaag
    54661 gagatataat agttcctaaa gactatgtgg gtgttgttat ggagctttgc caggaaagac
    54721 gtggaaatat gttaaatatg gaatatatag atgatagaag agtaatgctt cactatgacc
    54781 ttcctctcaa tgaagttgtt tacgatttct ttgatgcttt aaaatcaaga actagaggtt
    54841 atggttctct tgattatgag gttaaaggtt atgtagcatc tacacttgta aaacttgata
    54901 tattaatcaa taaagagcaa gtggatgcac ttagttttat tgtccatgag acacgtgctt
    54961 tccctagagg aaaggcaatg tgtgagaaat taaaaggaga aattccaaga catcagtttg
    55021 ctataccaat acaagctgct gttggtaata aggttattgc aagagaaaca ataagcgctc
    55081 taagaaaaga tgttcttgct aaatgttatg gtggagatat atctcgtaag aagaaacttc
    55141 ttgaaaaaca aaaagaaggt aagaagcgta tgagacaaat tggttctgtt gaagttcctc
    55201 aaaaagcatt tatgtctgtg cttaaattag atgagtaaat ccttataaat ttagataaag
    55261 atatttaaaa gctagagtga ttttagaatt atttctaaat tagtctagct tttttatggt
    55321 atattttaag taaactcata gagaatataa gtaagaatat taaagaagaa taaaaaggtg
    55381 atatttatga ttaatataga aattcctaaa aaagtagact atataattaa agaattagaa
    55441 aagaatggtt atgaagctta tatagttgga ggatgtgtta gagattgttt attagaaaga
    55501 gttccaaacg attgggatat aacaactagt gctagaccag aagtggtagt agaattattt
    55561 gaaaaaacaa ttccaactgg tatacaacat gggactgtaa cagttatgat tgaacatgaa
    55621 ccatttgaag tgacgactta tagaattgat ggaaattata gtgatggtag acatccagat
    55681 tcaatagaat ttacaaataa catagttaag gacttgtcaa gaagagattt tactatcaat
    55741 tcaattgcat acaattcaaa gacaggatta gtcgacccat ttaatggcta tgaagatata
    55801 caaaataagt atatacgttg tgttggaaat ccagtagata gatttgaaga agatgcactt
    55861 agaatgctta gagcagttag attttcagca caactcaatt ttaaaatagc tgaaggtact
    55921 aagcaaagta ttcataaaaa agcagatttg ataaaaaatg tttctattga aagaatccag
    55981 acagagttta ataaaatatt agtatctgat tcatctaaat taaacttatt aaaatcaaca
    56041 ggtttgttga aatttataat tcctgaaata tgtgaattag aagatgttac tcaacacaat
    56101 ccatatcaca tctatgatgt acaaaaacat actttaatag ctacagaagc aattgaagat
    56161 gaactgtatt taaaacttac aatgttgttt catgatttag gtaaaaaagt aactaaaaca
    56221 actgataaaa atggtgttga ccatttttat actcatagta gagaatctgt aaagattgca
    56281 aagaagattt tgaaaagact taagtatgat aattatacta ttaataaagt tttaatatta
    56341 atacaatatc atgattatag aatagaacct aaaaggaaga taattaaaaa gttattaaat
    56401 aaacttgaag atgttgaatt atttgaagat ttaataaaag ttaattgggc tgatacactt
    56461 gccaaaaatc caaagtatgc aaaacaaaag atattaaatc ttattgagtg tgaaaaagaa
    56521 tttaaacata taataaatca aaaggagtgc tttaatctta aagatttggc tattaatgga
    56581 aaagatttga tatctatagg tataaaacca ggtaaagata taggacatat tttaaataag
    56641 atgcttgaaa tagtcataaa taatccagag ttaaatgaaa aagaaatact aaaagaaaaa
    56701 gcattaaata tatatacatt ttagattcaa atataaaaaa tttaattact ttaaaaaaca
    56761 tagaataaaa tacttattta gataaaataa ataattttta gagaatattt tagaagttac
    56821 gattgtatga tttttaaatg cataggcatt tactctagga ctatagacta atataaaaaa
    56881 aaactttggg aatactaaaa ccataaattt ataaaattaa tattttatat actgtaaaac
    56941 agtgaggagg gacagtatgc atactcaact acaaaagact attggtcttt cagcagctct
    57001 ttctactgtt gtaggtatgg ttataggttc gggagttttt tttaagccac aagcaatata
    57061 cactacaact aatggagctc caggtctagg tattatagcg tggcttttag gtggttttat
    57121 aacaataact gctgggctta cagctacaga aatttcagct gctataccaa aaactggtgg
    57181 tatgatgatt tatatcgaag aaatatatgg agaaaagtta ggttttttaa ctggatggat
    57241 gcaaactgta ttatttttcc caggtacatc agcagcatta ggagtaatat ttgctcaaca
    57301 agcatctgaa cttttaggaa tgagcccaaa taatatggca aatgtacttc ctatagcagt
    57361 tggagttata ctatttttag cattattaaa tataataggt tcatccttag gaggaaaagt
    57421 tcagacagta gccactattg gaaagatgat acctttaatt ttaataatag tctttggatt
    57481 tattaaaggt caaagtagtg aagtattaaa tccatttgta ggagatggtg taaatgcatc
    57541 aaatgcactt ggacaagtat taatagctac tttgtttgca tatgatggtt ggataaatgt
    57601 tggagccata tcaggagaaa tgaagtctcc agagaaagat ttaccaagag caatagttgg
    57661 tggcttatca ttagttatgg cagtttatat tataataaat atagcttatc tttgggtagt
    57721 accagcaagt gaattagcaa cagttacttc cccagctaca ttagtagcaa caagattgtt
    57781 tggaaatata ggtggaaaag taataactgt gggtatatta atatcagtat ttgggacatt
    57841 gaatggatat ttattaacag gttcaaggat accttataca ttagctgaaa tgggaacttt
    57901 accagcatct aaaactcttt taaaagtaaa ttctggaggt tctcctgtaa attcaatact
    57961 acttataact gtgttagcct gtgtatatgc attatctggt caatttaatc ttttgacaga
    58021 cttaacaata ttttcaatat gggtatttta tgtattgact tttataggtg ttatgaggct
    58081 tagaagacaa aagccagatt tacacagacc atataaagtc cctttatatc caataatacc
    58141 aattatagct atattaggtg gactgtttgt aataataaat caaatattga cttcaacagt
    58201 catatcttta ggtgggatat ttataacact attaggttta ccagtttatt attatatgaa
    58261 aaaaagataa ctacttaatt taagttagat aaatttgggt aaaggtgaaa attaactttt
    58321 atccaaattt tttatactgt tatacaatat aagtattata tattacttga tgtgctattt
    58381 tgtttgattt ataatttagt aattgatgtt ttaagataat ttaagaaatg aggagtgaaa
    58441 gatgctagga ctttatgtac atattccatt ttgtgtgaaa aaatgtaagt attgtgattt
    58501 taattcttat aaaatggaca tagattcaaa aaaaagatat atagaagact taaaaataga
    58561 aatggaatta tatagtaata aattatataa agataataaa tataaaaata aagaatgctg
    58621 tagtctaaat aaaaatgaca aaataacgag tatatttgta gggggaggta cacctagtat
    58681 actaacctct gatgaaataa gagaagtatt tataagtata aaagaaatgt ttgatataga
    58741 tgagaatgca gaaataacta tagagtgtaa tcctgggaca ttaacattag aaaaattaaa
    58801 aactatgaaa gagattggca taaatagact tagtataggg ctacaagcta ttcaagaaaa
    58861 gcatttgaac tttataggaa gaatacatac ttatgaagaa tttgagaaaa actataaaga
    58921 tgcattaagt gtaggtttta aaaatattaa tatagattta atgtacagtc ttccaaatca
    58981 aactctatgt gattggaagg aaactcttga aaaagttgta cacttaaatc caacacatat
    59041 atcagcttat tcccttatac tagaagaagg aactgaacta tacaatatgt atgaaagtaa
    59101 taaatttgaa cttatagatg aaaatgtaga tatagaaatg tatgagtata caataaacta
    59161 cttaaagtca aaaggatata atcaatatga aatatcaaac tactcaaaag aaggctataa
    59221 ttgtgagcat aatattttat attgggaatg tgaacattat atagggattg gagcaggagc
    59281 ttctggctat attaatgaga acagatacaa taatgtagaa tctttagaag attatcattt
    59341 aagtttggta aaaagagaaa aaccaataca agaaaatgaa attctttctg agaaagatat
    59401 gatagaagaa aagatattta tggggcttag aatgaataaa ggcataaaat ttgaagattt
    59461 taaaaaaaaa tttggaatag attttagaga gaagtataat aagcaaatag aaatgctatt
    59521 agctagaaag cttataaatc agagctttga aggtatacaa ttaactcaaa aaggaagaga
    59581 aatatctaat agtgtattta tagaatttat ggaataattt ttaaggtgtt gacaaaataa
    59641 atttataatg gtatataata tatataatct ttttagcact cgaacttagt gagtgctaac
    59701 agctaggagg tataataata tggaattaaa tgaaagaaaa ttaaatatcc tcaaagctat
    59761 agttaaagat tatatagaaa cagctgaagc tataggttct agaacaatat ctaaaagaca
    59821 tgatttaggt gttagtgctg ctaccataag aaatgaaatg gctgaccttg aagaattagg
    59881 gtatttaatt cagcctcata cttctgcggg tagagttcca tctgaaaaag gctataagtt
    59941 atatgtaaac tctcttatga gtaaaagcga attggatgat aatgataaga ttcttattga
    60001 acaatgtatg aatcacaata taaatcatat aaaagaattg attcatgaaa cttctaagct
    60061 attatcgcaa ctaacaaact atacaactgt agcagttact aagagtttaa taaatcaaag
    60121 tgttataaag cacatacagt tggttgctat gaatgacaat aatattttac ttatagttgt
    60181 aacagataaa ggggacttaa aaaaagctaa ccttacaact aatgtatatt tagatcaatc
    60241 taagttaaat ttgatttctg ataatcttac aaggaagctc ttaggtaaaa gtataacaga
    60301 tttggatgat aatctaattg cttttattaa atacgaaata agtgagtatt ctgggcttat
    60361 agatgagctt ttaaatgctt tgaactcaaa tatgaaagaa gaagattttt ctctatcatt
    60421 aaatggagct actaacatat ttagttatcc agaatttaat gatgtattaa aagcaaagtc
    60481 atttttaaat atgttggaaa aaaaggaaac aatagctgac ataattaaat caaagggaat
    60541 acaaaaagac aatctaaata taataattgg tagtgataat gattgtgaac tggcacagga
    60601 ttgtagtata gttacagcaa cttataatgt agatagagac ttggttgggc gaataagctt
    60661 tataggccct accagaatgg attatgctag aatttactct ataataaatt atatgagttt
    60721 attaattaat agaaagtaaa gaaattttaa attgcgaggt gtaaagtctt ggataaaaaa
    60781 aatgagcaac aggaagtaag agaagaaaat gatacttcta ttaaccaaga atcggaaact
    60841 caagtagagt tagaagagga agttgttaat gaagaatgtg aaacatcaag tgaaaaaact
    60901 gatgaaaaag aagttgatga tgaaaatgta acagatataa attctaagtt agcagaaaaa
    60961 aaattgcagg atgagttgga tgaattaaat gataaatatc aaagacttca agccgaatat
    61021 gcaaactaca gaagaagaac tcaacaagag aaagagacaa taggcgtatt tgcaaatgaa
    61081 aaaataataa ctgaattgat accagttata gatagtatgg aaagagcctt agatgcatgt
    61141 gaagataagg aagatactat gtataagggt ataagccttg tacataaaca attaatagac
    61201 actttagtaa aatttggagt agaagaaata gaagcagaat ctaaggaatt tgaccctaat
    61261 ctacatctag cagttatgca agaaagtgta gatggagttg aagcaaatca aatagtaatg
    61321 gtacttcaaa aaggatataa gctaggaact aaagttgtaa gaccttcaat ggttaaagtt
    61381 tcttgctaag tataaattaa aggttaaatt atttaaccta atataaaata ttaaaataag
    61441 taaaacttaa ttatataatt actcgaggag gattttagtc atgggaaaaa taataggaat
    61501 agatttagga acaacaaatt catgtgttgc agtgttagaa ggtggagaag cacaaataat
    61561 agcaaatagt gaaggtatga gaactactcc atcagtagta gcatttacaa aagatggtga
    61621 aagaatagtt ggagaacctg caaaaagaca agcagttaca aatgcagata aaacaataac
    61681 ttctataaaa actcatatgg gaactgatta taaagtaaat atagatggaa aatcatatac
    61741 tccacaagaa atatcagcaa taatattaca aaaattaaaa tcagatgcag aaagttactt
    61801 aggacaaaca gtaacagaag cagttataac agtaccagct tactttacag atgctcaaag
    61861 acaagcaact aaagatgctg gtagaatagc agggcttgat gttaagagaa taataaatga
    61921 gccaacagca gcagctcttg cttatggtat ggataaatta gaccaagaaa agaaaatatt
    61981 agtatttgac ttaggtggag gaacttttga cgtatctata cttgaaatag gagatggaac
    62041 ttttgaagtt ttagctacag ctggtaacaa tagattaggt ggagatgact ttgaccaaat
    62101 agtaatagat tatttagcag aggaatttaa aaaagctgaa ggtgtagatt taagaaatga
    62161 taaaatggct cttcaaagat taaaagaagc agcagaaaag gctaagaaag aattatcatc
    62221 aacaatgagt tcaaacataa acttaccttt cataactgct acagcagaag gaccaaaaca
    62281 cttaaatata gatttatcaa gagctaaatt tgaagaatta actagaggtt tagttgaaaa
    62341 aactatggaa ccaactaaga cagctttaca agatgcagga ctttctacag gtgatataga
    62401 tgatgtatta ttagtaggtg gttctacaag aataccagca gtacaagaag ctgttaagaa
    62461 gtttatagga aaagaacctc ataaaggtat aaacccagat gagtgtgttg cagcaggtgc
    62521 ttctatacaa gctggagttt tagcagggga tgttaaagac ttattattac tagatgttac
    62581 tccattatct cttggtatag aaactatggg taatgtaatg actaagataa tagaaagaaa
    62641 tactacaata ccaactaaga agtctcaaat attctcaact gctgctgata accaaacagc
    62701 tgttgatata catgttcttc aaggtgaaag aagtatggct tatgacaata caactttagg
    62761 aagattccaa ttaacagata taccaccagc acaaagagga atacctcaaa tagaagttac
    62821 ttttgatata gatgcaaatg gtatagttaa tgtttcagct aaagatttag gtacaggaaa
    62881 agagcaaaaa ataactataa catcaaacac taatttatca gaagcagaaa tagagcaaaa
    62941 gataaaagaa gcagaaatga atgcagaagc tgacaaacaa aagaaagaaa aaatagaagc
    63001 attcaatcaa gctgaatcta ctatatatca aactgaaaaa actttaaatg aacttggaga
    63061 taaaataagt tcaggtgaaa aagaggatat agaaaaagct atagcagatt taaaagctgt
    63121 aaaagataat caagatgcta cagcagaaga acttaagaaa gctacagatg aagtaatgac
    63181 taagttccaa aaagtatctc aagaaatgta ccaaaaagca gctcaagaac aacaagcggc
    63241 acaaggtgca gaacaagcac aagacaatgg acctaaagat gacaatgtag tagatgctga
    63301 ctttaaagaa gtagatgaag ataaataagc tatataatat gtaacactaa atgataattg
    63361 gaacatatat gatttgtgaa aatcatatag atgttaaaga tatatggaca atatacatca
    63421 taaagaatat aatatatcat agattatata acttaaagta gaatataaga attaatgata
    63481 gcttgtagtt tattattcta caagctatcg ttttgtaaaa tgaaggtggt gtcaattttt
    63541 gagtacaaaa agggattatt atgaagtctt aggtatcagt aaaggtgcag aagctcaaga
    63601 gataaaaaaa gcttatagaa aattagcaat gaagtaccat ccagatagaa atcctggaga
    63661 taaagaggcg gaagaaaaat ttaaagagat aaatgaagct tatgaagttc tatctgatga
    63721 tacaaagaga aaaacttatg accagtttgg acatgatggg ctaaatggtc aaggcggttt
    63781 tggtggtcaa ggaggatttg gcggtcaagg ctttggtggt tttgaagata tgttcggaga
    63841 tatatttggt gacatgtttg gaggaagctt cggaggtgga agagcaagaa gaagaggacc
    63901 tcaacgtggt gcagatataa gacagagtgt tactatatct tttgaagaag ctgcatttgg
    63961 taaaaagatg tctataaaag taaatagaag tgaagagtgt gaagaatgta atggaactgg
    64021 agcaaaacca ggaacatcaa agaaaacttg ttcaacttgt aatggaactg gtcaagttag
    64081 aactgttcaa agaactccat ttggtaatat agcaagttca agaccatgta gtgcttgtaa
    64141 tggaactgga gaagtgattg aatctccatg tagtaaatgt catggaactg gaaatacaag
    64201 aaaagttaag actatagaag tagatatacc tgctggtata gatgatggtc aaatgataaa
    64261 actttctggt caaggtgaag taggagaaaa aggtgctcca agaggagacc tatatattgt
    64321 agttaatgtt aagtcacatc cactatttac tagagatgga aatgatattt attttgaaat
    64381 gccaattaca tttgttcaag caactttagg tgatgagata gaagtaccta ctttggatgg
    64441 aaaagttaaa tatagtgtgc cagaggggac acaaactgga actgtattta gacttaaaga
    64501 gaaaggaatc cctagaatta gaggtaattc aagaggagac caatatgtta aggttgtagt
    64561 tgaaattcct aaaaaattaa acgataagca aaaagaacta ttgagagaat ttgcgaagga
    64621 gtgtgggtcg aacgtccacg aaaagaagaa aaccttcgga caaaagatag aagatatgtt
    64681 taagaaaaag tagttaaagt agccaatata taatcatatt tttaaaatct tagttattta
    64741 taagattgtc aaaggagata ttatgatttt tatattggct atttttgtat aaaaaataaa
    64801 tgtgcataaa ataaaactga atataaataa ttttctgaaa aatacttgtc ctaaaatata
    64861 taatgtgcta taatataatc aaataaaaga aaggggtgat tccagtggga acggatgtgg
    64921 cactgccaaa tgatgaagaa aactttattg taatatacaa aataaaatta gatactttta
    64981 gtgctagatt aagtactgga aaaactcatg agctgggata attattgtaa ttacctagac
    65041 tcaaactttt agtagtaaaa tagtaatatt atatagacaa ggtatctaat ttttaaatct
    65101 tttgtatgaa ttaaaatttt tataaagggt atatctgatt agaatgtaat tagggaaacc
    65161 tagttgtgaa ttacttttag tatatacatg tgtaaagaaa tatgtatatg gtattggtta
    65221 ttgtgctaga tgtgtatgta aagaaatatg tgtctagttg ggtatatgta aagaaatata
    65281 cttataatct atgaaaaatt tttagtataa attgctaaaa cattgagatt gttttttata
    65341 gaaagttagt ttataccaac taaaaatgtg cttaagattt gtttgatgtt taattataaa
    65401 taaggttgta gataaaaaaa taagtaaaga caaaggttta aaatacttgc tttaaatata
    65461 gtttgttttg aacacttgcc aaattaaaat aattaataaa atagacatct tctcatagta
    65521 aaatatactg tgagaggatg tttttgcttt gttcataaac ttttatgaaa aatttgcata
    65581 gtgtcacatt ttaatatact atatatataa taaaatatag ataaaattaa atgattcaaa
    65641 agagaaaggt gaaaagagat gtattatata ggtgtagaca taggaggaac aggtatacaa
    65701 gcaggagtag ttgataacta tgggaaaata atttttaggt cagagtgtaa aacagtaatt
    65761 gaaaaaggat ttgaaggaat acttaatgac ataaaaataa tgatttataa gttgttggaa
    65821 gataataaac ttactatgag tgacataaaa tctattggat ttggtgttcc aggttttata
    65881 aataaagaag gattagtaac ttgtgtaaat ttaaaatgga ataaaaaagc ttttaataaa
    65941 gagttaaaaa gaagatttcc agatgttgaa attcatggag aaaatgatgc aacagtagca
    66001 gcacttggag aggcaaagtt tggaagtatg aaaggtgcta atgttggagt attatatact
    66061 ttaggaactg gtgtaggtgg aggaatagta attaatcaaa aagtcttttc tggagcacat
    66121 ggattgggtt cagaaatagg tcatcaaatt ataggagaaa actattttaa ttgtaattgt
    66181 ggaaataatg gttgtgtaga aactttttgt tcagcaactg caattataaa gtattctcaa
    66241 aaactgatag aagaaggaga aaagagtagg attttagatt tggcagaggg aaatttagaa
    66301 aatgtaaatg caaagatggt gtttgatgca tatagagaaa atgatttagt ggcaattaaa
    66361 gtaataaata gatttaaaga gtatttagca aaaacttttg caaacacaat aaattcttta
    66421 gacccagaaa ttatatctat aggaggaggc atttctaaat ctagcgatat aatacttgat
    66481 ggaatagaag atttggtaag aaaatttgta ttatacaaaa cagaagatat agctacaatt
    66541 acatgtgcaa ctttaggttc agacgcagga attataggag cagctttttt ataatgtaaa
    66601 tgaactgctt attggaggcg tgatgatata tgggtaaaac aaatgctaga agaacgcttt
    66661 ttttgatagc aataggttca ggaactatgc tgaatcctct taattcttct atgatttcac
    66721 ttgctttaca tagtatacaa aatgattttc atattagttt tacaactgta tcttggattg
    66781 tttcagcatt ttacctagct agtgctattg cacaaccagt ttcaggtaag ataggagatt
    66841 taataggtag aaaggtctta tttttgagtg gtttgatgct tgtaatttta tcagcatcca
    66901 tagtaccact tgttcaatca ttctttatat tgatttttat aagagtaatt caagcaattg
    66961 gaacaagtac cctatatcca tctggagttg ctcttataca aaataatata aaagaaagac
    67021 aatcttctgc attagcagtt ctaaccattt ttgcttcaac tacagcagga ttaggtccga
    67081 cacttggagg attattgttg gacttaggag gatggcatgc tatatttctt gtaaatatac
    67141 ctgttgtttt ggtttctata tgcttagggt attttttatt cccaaaagaa gtaaaagaaa
    67201 agaaatctat aaaagaaact ttaaaaaatg ttttgtcaag attagatatt attggcatac
    67261 ttctattttc aattgcaatg atttttatat tactattttt gctatctatg aaggagtctt
    67321 ttaacttaga acaacttata tttggtataa tactgatgtg tctttttatt tggcatgaat
    67381 tgagaacaaa attgccattt atagatatta agctttttgt aagtaatcct aaattgtcaa
    67441 aagtttactt gcaatttatt atattaaatt tctttaatta tattttgttt tttggtcttc
    67501 ctagttattt tcaagatgcc ttacattata gtgcaaagtc gactggatta tttatgctat
    67561 ttatgtctgg tataggtata tttatatctc cattaactgg aaaatggata gataaatctg
    67621 gaactagatt tcctcttgtt acatcatcaa tctttatgtt tattagtgca gtacttcttt
    67681 cagtagtttt tatccatata cctgtaatag gaaagggtat tatattatca ttagcaggta
    67741 ttagttatgg agttggtaat gtagccctgc aatcctctat gtttgaagaa agtcctcgtg
    67801 acagtatagg gacagcttct ggtttgtttc aaactagtcg ttatttaggt tctattttag
    67861 caactgtttt acttggaatg gtatttgaag taaatataac atcagaacaa tttcagatat
    67921 taggttatgt tatggtggtc ttaggtacaa taagtttttt attaaatttt atattaaaga
    67981 aagaattaag aaaagtagaa tagtggattt atggatttaa taagtctaat aactgataag
    68041 tttaaaaata ttgtttgtaa aacataactg gtttggtatt tattaattct aagttttgaa
    68101 gcatagagta ctcgataagt atacaatatt ttgaattaaa attaagcaga aatttgaact
    68161 agtctttcaa atctctgctt aatttagtag ttaaattttt ttatagagaa aataagattt
    68221 gacacttaga taaaaaatca ttgcattttc aaaattcttt aaatcaaacc caagtatctc
    68281 attaatcttt tccaatctat atactagcgt gtttctatgt aaaaacatac tagtagatgt
    68341 cttagaaata tttaaatcat tatttataaa ttttattcct gtatatagaa gttcttcgtc
    68401 aatagattta atcttattaa aatctattaa tttattgagt atattatcct cattaattaa
    68461 atctaaagtt ttatatctaa taaggtcaaa caaatttaaa aacttatttt cagcgttgtc
    68521 ttttataata tgaggtagta aatcagaaca taactgtaat ctaaaatcaa aatcagcttt
    68581 actatctaat ttaccaagat aaaaaatata agtactttga taagtttcag tttcaattat
    68641 attttgtgta gttacattaa tatctaagtt atatttagaa tttactataa aaaaaccatt
    68701 gtgttgtatt atatttatat cttcaaataa attataaaaa atatttttta gatattcaaa
    68761 gtctatatga gattggtaaa ttaaataaaa gttgcctttt aaattatcga gattattttt
    68821 atctagaaaa tcaataacat aaatagcatt attgaaagta actaaatggc tactagcatc
    68881 taacttttgg ttttcatatg gatagatatt tattttttta ttaagctgtc tttctaaaaa
    68941 atcttttaac tcttccataa agtctcctta aaaataagat tatattctta tcttatagct
    69001 aaagtagttt ctttgtcaaa tatgtgtact ctactattgt caactgaaag tgttaagtca
    69061 tcaccaacat taattctgtt tttactgtca aatctaattg ttatcgtatt ttcgcctagt
    69121 tttaagtgag cataagtttc tgctcccata agttctttta tttcaattct tgatttaaaa
    69181 caagtatctg gattagattt aataaaagta tcttctacat gaatatcttc tggtctgata
    69241 cctataacaa cttcattatt aatataattg tcttttatta aatcatagtg tttttcttta
    69301 ttcaatttaa gcttaatatg ttcattttgt gcataaattt catcattttc ttctattaat
    69361 attacatcaa taaaattcat ctgtggtgct ccaataaatc ctgcaacaaa tatattagct
    69421 ggataatcgt atacatcttg tggagttgca atctgctgaa ctactccatc cttcattact
    69481 acgattctat cagccatagt catagcttca acttggtcgt gtgttacata gataaatgta
    69541 gttccaagct gttggtgtag cttagttatc tctgttctca tagcagttct aagttttgca
    69601 tctaagttgg atagaggttc atccattaag aataccttag gatttctaac tattgcacgt
    69661 cctaaggcaa ccctttgtct ttgtcctcca gataatgttt taggtttttt atttaaaaga
    69721 ggtagtaaat ctaatatttt agcagcttct ttaacttttt tgtctatttc atctttgggt
    69781 aattttctaa gtttaagtgc aaatgccata ttttcgtaaa cagataaatg gggatataaa
    69841 gcatagtttt gaaaaaccat agctatatct ctatcttttg gttctatatc attgacaagt
    69901 ttatctccaa tgtatagttc tccttcagag atttcttcaa gaccagcaat cattctaagt
    69961 gtagtcgatt taccacaacc agatggtcct actaaaacga taaattcttt atctttaatg
    70021 tctatattta tattttttac tgcgttaaat ccatttgagt aaagttttga tatatttttt
    70081 aaaattactt ctgacataat atcctccttg atatttaaat tttaattata tagtatcaaa
    70141 tttttttgtt atattaaatg tgtaaaatga ctaaatgtat ttgtttaata tgtatattta
    70201 gtttttagca aagaataaaa ctaacagtaa agtatattta aaaaattaaa aaacaaaatt
    70261 aaatttatta tcaaaaaatc attttatgat atgttttatt tttatattac aaatagagaa
    70321 taatgaatta tactagaaag taggaggtga aaatatgagc agaatttcaa tttttatgga
    70381 atcatgtaat ggcaaatttc caaatgaaaa ttcaatgttg tcagtttcct ttataaaaaa
    70441 tattttaaat gcagaaaaca aagattttgc taaaaacata tttaactatg ggaaagaaag
    70501 aaaaaacaat aagcaaataa aggatataaa tacagccatt tacataccaa atcttataag
    70561 aagcaaaaat gagttacttg ttgatggaga tataatattc aatataagtt tttataatta
    70621 ttctatgttc agtaaattat acaatggaat tttaaaagta aaggagctag aatataaagg
    70681 ttatagattt aaaataaaaa atataaaaat acataaagaa cacgagataa aagaaaatgg
    70741 tgttatattt aaaactatgt ctcctataat agtaaagaat aaagaaggta aatatttaga
    70801 tgtagaagat tcaaattata tagaatgttt aaactatata gctaatctaa ctctggagag
    70861 tataagaggt agtgggctta gaaagccatt ggaatttata cctcttaact tcaaaaaaag
    70921 agtgttaaaa gaaaagattc gtggatttaa agtgagagaa ttttactata taaatgctta
    70981 tgcaggaaca ttttttttaa aaggagatat ggaagattta aatgcactgt ataaaatggg
    71041 aattggatat agaaggacgg aaaatgcagg aatggttgat atattaaagt agcgaggtga
    71101 gagaaataaa agctaaattt tatagatcag gtgatattgt aagagatatt ggcattgttt
    71161 acttttatga attactaatg gatttaaaaa acgaactaga aaaaaatgat tataagctaa
    71221 aatttacttg tgagttaaat agaaattatt tatctttaga atctgcagaa tatatagacc
    71281 ctaagtatat atctgattat atattagaaa atcaactttt taaggtattt aaaaatggga
    71341 aaaaggaaac cttagaaaaa atatttagta atatagataa tttaacgtat gtaaatttta
    71401 ttgaagaatt ggataaatct tctgcaactg ctaaacaaaa ggaagatatt aaaaaagatt
    71461 ttaaaaacag gaggtttcca tatgttagaa atagtggtaa gtatggatta aacacgagtt
    71521 tagaaaatat ggaaacaaat gtaaaaagaa tagtagatac tgtaattaaa tcaaatatag
    71581 agatagatga aatagataaa cttgatttga cacaatatga agaaaaagat agtgtatgta
    71641 atgtttgcaa tataaataaa acaacaaaac tagatattga tttaagagaa cgaaaggact
    71701 ctaagtataa ctttttattt agaggtgcag aaaaatcagg ctttaaaaga agtggacaag
    71761 ttgaaagtaa tatttgtttt gagtgtgaat ttttcaactt aatgtgtctt ttatatataa
    71821 atttaaaaag accaatggtt tttgcatata cgaatgattt aagagaatta gcatttttaa
    71881 atcataagat aatgcttaaa agaaaaatgt attcagataa atcattttat aaaaaacttt
    71941 tgcatgaaaa aataagttca attagactat atagatttga tattgttaag aataaaggta
    72001 taattctaaa gtttgactct attatagagt ataaagaatt attaaaaaaa attgaactta
    72061 tagatattat agataattat aatttctcaa gggagccagt aaacactaaa aatttaggta
    72121 aaaaaatgat tgataatgga aatttatcaa atttaaaaga attattactt gataatataa
    72181 gttttttaaa gcaatcaact ggaacttctc gagaaatgga ttttgtatct agctcatata
    72241 atatcggttt atatataaaa ttgtgttgga ttgtagatgg aggggaggag tataaaatga
    72301 aaaactatat ggaaagtaat ttaatatatt caagagtagg taaagactta tttaataaaa
    72361 tgacagatga atccagaaga aaaaattttt ctatgaaagt gattcaacta cttaagtcta
    72421 atgatagaac tcagctattt caaactataa tgcatgtgtt agtttctaat ggaatcttaa
    72481 taggagaagg gtttgtagaa ggtctaatgc agagttctga attagaatta aatacgaatg
    72541 taggtctatt tattcaagaa atcatgaaat aaaaaagggg gaaaatttaa aatgaatgaa
    72601 aaaagagtaa aaggagtaac attaactata ctgacagaaa gcccagttcc actttcatat
    72661 gaccaagggt atggaaatta tacaccaata aaaaaagaac aatatagaga aaaaatacat
    72721 gcaaaaacta gtatagccac aataacatat gatttaagaa gaatgctcca ccaagaatat
    72781 ggttggaatt taagtaatat tgtttttgga aaaaaaggaa atatatatcc atctattaag
    72841 aaaaatgtag gatgtgtaga tgaaaatgga ttagagactg atgtatttgg ttatttgata
    72901 ccacttaaag ataaaggttc tataagtaaa gcttctccac ttagaataat accttttagg
    72961 tcattaaatc catatatagg ttcaacacag ctaataacaa atagaggttt tttaagtagc
    73021 gaatttggta gaaaatatta tgatgagaag gaagaaaatg aagtacctag agatgaaaac
    73081 tttccaacaa cacaagcatt agcaatagaa gagactttat cagattacta cgtttataca
    73141 ataacattgg agcttgatag aataggagta gtagaagtag aagatgggaa gttactttta
    73201 ccagaagaaa gaaaatttat gagtaaggaa ttaagagaaa aggcagtaaa agatatatta
    73261 gatgcaatta ctgtgtttac aagaaacata aaacattcat cagtactatt aaaaccactt
    73321 gcagtaatag gtggagcttt tgataaagtt gtaccatttt tttgggatga tgtagattat
    73381 aacgctgata gtggtgagat aaatttagag ggagtcatag aaactataga aagttatagc
    73441 cttaaagaaa gtaacacaat acttgctatc aatgacagat taaaaatttc taataaaaag
    73501 gaattaaata agtttaattt aagtaaatac cctgtaaaag agattaaaaa tctagcagat
    73561 agattggaaa ttggagaaga taatatgtgg tatttaaaag agtaggaggt tttttgaatt
    73621 atgaaagtat tacaatgtaa acttaagcaa ccaactgctc actatagaga cccaaaagta
    73681 tttcaaaatg aatatataag tactttaaat ttaccatcta agaccacaat aatgggaatg
    73741 ataacgtatt tatgtgatag aagattaaac tctgatatag atataggaat aattggaaca
    73801 catcatcata gagaactaga attttcaaga ggagagaaca ttgatttttg gaatgaatat
    73861 acaaatatga gaaaaggcaa agataaagaa aagtttttgc ttcaaggaaa ctactatgat
    73921 tattataaag aacataaagc tcaaaatagc atattaaact atgaagttct taaagaagta
    73981 gaactgacta tatttatttc ttgcaaggat gatgaagaac ttgaatttat taaaaaaaag
    74041 cttgaaagtc catgtaaata tgcaaattta ggaagaaaag aagattttgt aataccaagt
    74101 gaaaaagggt gttttgtgaa agaagttgag ttaaaagagg ttatacctat gaatactcgt
    74161 gatgctataa aagaaaatat aaaattaaag aatacatatg taagagttga cttaagagat
    74221 aaagagaatg tcgagactat aataaatcaa ggtgtattga ttgcattacc tcataaatat
    74281 aaagatttag aagcaaatag agatgataga gtttatgagt tttgtcatta tatatatgtt
    74341 gataatgatg gtatatatcc taaaaatatt aaggtaaatg tatgtattga tacaaaagaa
    74401 gtttttacat ggctttaaat tattttgaaa gataggtgtt tatcatgaaa aatatcatgc
    74461 aaaaagaaat attagctaag tcatacaatt taagaactaa tcaacaagag caaacattag
    74521 ttgaacatat taaggattta tttgaagtat tagaatctat attagaacta aatctatatt
    74581 cagataaaga tgtagagata ttgaaaatat gttgtgcttt gcacgattta ggaaaaatta
    74641 attcaattat gcaacaaaaa atggagatta ataataaaat atcgtatagt tgctcagaag
    74701 aagagaggaa aaagttagag tctgacaaaa aatctttaaa aaagatagca agacataata
    74761 tattttctgg agcattttta aaagatatat tagaaaaaat gaacttgtca gaagaagata
    74821 agttatatat atataaaagt ataatgttac atcatggaaa ctatgaagat tatatgaggt
    74881 taagtattag taaagttcaa gaagaaattt atgagtatat tgaaaaaggc attttagaaa
    74941 aagaagagtt taatctgaaa gatatagaaa gttatataaa taacatttta aatgtagact
    75001 ttaaatttgg tgaagatgta ttggattatg attacataga taaattaagt gaaagtatgt
    75061 ttatagacag tgattataac aatggtcaaa tagatgattc agttttaaat tatagaaagt
    75121 ttaagtatat tttatataaa gggatgctga acttaataga ccatagtgca tcaagtagac
    75181 agaaaggtat aaaattttat aacgatttta ctgatgaaga aattgataat atgattttaa
    75241 atgagatata taagagtcag ggtaatttag aaaaaaataa tatagagttc aatactatac
    75301 aaaaaaggtt gagagaactt tctggaagaa atgttctgac tgttgcattt acaggttcag
    75361 gaaaaacagc tgcagattat agaaagactt ttaaaagaaa attcttttta gtgccaaata
    75421 aaatatcagc agaaagtttt tatagaaaaa atatttttca aaataaaaat gatttagata
    75481 caagaagtag taatgattac attggattac ttcatggaga tataaactta tattcagaga
    75541 atgaagataa tggagaacat gattttgtat tgacattaag ggatatagat ttgagtataa
    75601 acttttgtaa accttgtgta attgcaacag ttgaccagtt attacttagt atgtttaaat
    75661 ttccgggata tgaaaaaata ttcgcagccg taaaaaatgc atctataact gttgatgaag
    75721 tacatttatt ggaaccaaag atgtttttga ttttgatata ttttatgcag tttgcatgca
    75781 agtacttaga tgttgatttt cacttaatga cagctacact tccaaaatca tataaagagc
    75841 aaatgataaa caagggaatt atttttcaag aagaaagtaa taaaaatgtt actgataaag
    75901 gagaaatagt ttttattgag agcaacaagg aagaagagat ttgtgaaggt aaagatgtaa
    75961 aggtttcttt tataaaggaa aaagaaatca agtcaatagt tgaagatgct ttagaaaata
    76021 aacaaaaaat tcttataata aagaatacta ttgattcagt caatagaaca tatgagtttt
    76081 taaaagaaaa tttatctgat aagtatggtg gtgtagatat agatgtttta catagtagat
    76141 ttaagttcaa agataaaaaa gagaaatata gtaaaatatt aaatggagag ggtgatattt
    76201 ggatatcaac tcaatcagta gaaatatcct tggatttgga tttcaatata ataataagtg
    76261 atttagcaac tatggatagc ttgatacaaa gaatgggtag atgcaataga aataataaat
    76321 atgaatatgg aaacttttat attctaccta gtgaagataa aatttatgat aacaaactta
    76381 agaacacaac taaaaacatc ttaaaggaca tattaaaaac taactctatt tttacaatgg
    76441 gaattagaaa aactattttg gatgattact atgataatag tgtagtcaaa aaatattttg
    76501 aagagaattt tataagttgt gataaagaaa ttaagaatat ttatggtata aataaagaaa
    76561 tttttgatgg attagattta atttttaatt ttgaacctta caaaaatatt gttgatagta
    76621 agaaggaagc agctaaaatt tttagagata ttgatgttag ttacaaaatt attctggaag
    76681 aagattttta taaggaagat agggagttac aacaagattc gattcaagta tcagggttta
    76741 tatttaatag attatattat tatggattaa taagtaaagt agaaggatac atggtactaa
    76801 aatctagtag taagtttgag tataatagta ctgtaggctt aattttgaag tgagcatatg
    76861 tttaaatata atataccttt agccattgaa aatacaaaaa gtactactgt aagtccactg
    76921 taaaaactat tttttaaaag gaaaaataag ttgtgagata gagtgtttac aagtgtatat
    76981 agataataaa tttgaggttt aagattaact aagtgggttt caggtacatc gcgaaaataa
    77041 ttataagttg gagattttgt atgtttaaga ttaactaagt ggatttcaaa tattgatata
    77101 gtagatataa tagaagtttt attattaggt ttaaaattaa ctaatcggat ttttaaatat
    77161 tctgactatt atataaggat attattagct tgaatttaaa accaataata taaaacaaca
    77221 aaatattata tttatgatat aataaaagtt atggaaaaac aggaatatta ctatagagaa
    77281 gagaggtaaa cttatgaata attggataga agtaactata aaaacaacaa cagaagcagt
    77341 tgaacctata acgaatatac tatatgaaca aggagctgga ggagctgtaa tagaagaccc
    77401 aaaagacttt ttattccaaa agaaaaatga actagactgg gattatgttg aagaagaagt
    77461 atttaaaaag aatgaagaag atgatgttct tataaaaact tatgtttctg aagaaaaaaa
    77521 tgtgatggaa tttgtcgaaa taataaagca aaaagtttta ggattaaaag attttggtat
    77581 agatataggt gaaggaagtg tatcattgga ccaagtaaat gaagctgatt gggcaaatgc
    77641 atggaaagca tactacaaac caacaaaagt aggacaaagg gtagtagtaa aacctacatg
    77701 ggaagattat gctatgcaag agggggattt aatcatagag cttgacccag gaatggcatt
    77761 tggtacaggg acacatgaga ctactagtat gtgcattaga gaattagaaa agtatgtgaa
    77821 taaagattct aaagtatttg atattggctg tggtagtgga atccttgcaa tagcagcagc
    77881 taaattagga gcaaaagaag ttgtagctgt agatttagat gaagtggctg taaaagttgc
    77941 aaaagaaaat gttcttgaaa ataaagttga aaaaagtgta tctgtaatgc atggtaattt
    78001 aactgatgta ataaaagata aagcggatgt aatagttgca aatataatag ctgatataat
    78061 aaagatactt gcaaaagatg ttcaaaactt tatgaaagaa gatgctatat tcatatcttc
    78121 aggtataatt ttggataaag tagaagaagt taaagaaagc ttaattgaaa atggatttga
    78181 aatagttgaa gttcaaaaat taggtgaatg gtcagcaata gtttctaagc ttaaaaaata
    78241 agggatatgg tgacgtataa tggatagatt ttttgttgaa aaaaataata taaatctaca
    78301 agataaaact tgcactatag aaggtgaaga tgtaaaacat atttcaaaag ttttaagatg
    78361 caaattaggt gagaaacttg aaatatgtga caagaataat aatgagtata tttgtgagat
    78421 aatgaatata gataagagta tagttaattt agaaatttta gaaaaagttg atataaatag
    78481 agaatcagaa cttaaagtaa ggctatacca gggacttcca aaagctccaa aaatggaaat
    78541 gatacttcaa aaattaactg aagtgggtgt agaagaaata atattagttc aaactaagag
    78601 aagtgttgtt aaagttgatg acaaaaaaga agataaaaaa tttgaacgtt gggaaagaat
    78661 aatttatgaa gcagcaaagc aaagcaaaag aggtaagata ccaaaattaa gaggtgtttt
    78721 aagttttaaa gaagctttag aagatatgaa aaaaaataat gtaaatattt gcccttatga
    78781 aaatgaaaga acagtttcaa taaaacatgc actaaaaaaa tgtgattcta atatagatag
    78841 tgttggaatt tttataggtc cagaaggtgg attttctgaa gaagaaatag aacaaataca
    78901 aaaaaataat tgtaatgttg tatcattggg gcctagaata ttaagaactg agacagcttc
    78961 tgttgtagca tcaacaatag ctttgtatga actaagtgat ttaggaggag aaaaataaat
    79021 tgaaaaaagt agctttttat acacttgggt gtaaagttaa tcaatatgaa acagaagcta
    79081 tgctagaact atttgagaaa gatggttatg aacaagtcaa tagtgaagag tatgctgatg
    79141 tttatgttat aaatacatgt acagttactc atatgagtga tagaaaatct cgtcaatata
    79201 taagacgagt taaaaagaag aatccagatg caataatagc cgttgtagga tgttattctc
    79261 aggtatctcc ggaagaaatt ttggatatag aagaagtaaa tttagtcatg ggtacaaatg
    79321 atagaagaaa gattgttgaa gaaattaaaa agataaattc aagtaagaaa gttagtacag
    79381 ttgacgacat aatgaaagtt aaagcttttg aagaaataga aatcagccaa actaatggaa
    79441 agactagagc atttatgaaa atacaagatg gatgtgacag attttgtact tattgtatca
    79501 ttccttatgc ccgaggacgc gttagaagta gagatattga tagtatagtc gatgaagtga
    79561 aaaaattggc taataatggc tataaagagg ttgtattaac aggaatacat gttgcctctt
    79621 atggaaaaga tttaaaggat agggatatta aacttcttga tgtaataaaa caaataaacc
    79681 agatagaaaa aatagaaaga attaggctta gttctgttga accaatttta tttacagatg
    79741 aatttgtaaa tgaagtttta aagatggata aagtttgtcc tcattaccat ttatcacttc
    79801 aaagtggatg tgatgaaact ctaaaaagaa tgaatagacg atacacaact ttagagtaca
    79861 aaactattgt agatagattg agaagtaaaa tgccagatgt ggcaataact acagatgtaa
    79921 tagtaggttt tcctggagag acaaatgaag agtttaaaaa aacgtacgag tttttaaaag
    79981 aaatagagct ttcacaaatg catattttta aatattcacc aagaaaagga actccagctg
    80041 caactatgga aaatcaagtt gaccctcaaa tgaaacactt tagaagtgaa caacttttaa
    80101 atttaagtaa agtaaatttt aataaatttg caactaaatt tatcggccgt gagttggatg
    80161 ttttgtttga acaaaatata gaaggcaata aatatgaggg attaacttca aattatataa
    80221 gagttgttgt tgaaagtgac aaaaatatac aaggtcagat attaaaagtg aaaataaatg
    80281 atgtaaaaga tgaatatgta gaaggaattt tgctataaca tgtagaaatt ataatattta
    80341 taagatagga ggtggaaaga atggattgta ttttttgtaa aatagcgaac ggagaaatac
    80401 cttcaactaa agtttatgaa gatgatagag tcttagcttt taatgacttg aacccagttg
    80461 ctccatatca tatattagtt gtacctaaaa aacattatga tagtttaatt gatattcctg
    80521 ataaagagat ggacattgtg tcacatattc atgttgttat taataaaata gctaaagaga
    80581 aaggttttga ccaaactgga ttcagagtca taaataattg tggaagtgat ggagggcaag
    80641 aagttaaaca tttgcactat catattttag ctggtaaaaa gcttcctaat tacgaagcgg
    80701 gacaaaacta aactaaatta ttgaaaaatt gagttccttc ttgataaaaa tacttgataa
    80761 aagtaaaaat ttagtttata ataaacaaag tgttaggttg taatgcatat tatgcaaaaa
    80821 gaacatagtt acagtcccag cataattgcg ctattggagg gagggaaaaa gaaatgtcag
    80881 aagtaagagt tagagagaat gaaacattag acagcgcttt aagaagattc aagcgtcaat
    80941 gtgcaatgtc tggcatcatg tcagaagtga gaaaaagaga gcactatgat aagccaagcg
    81001 ttaagcgtaa gaaaaaagct gaagcagcaa gaagaaaaaa cgctaagaaa tagtagtaaa
    81061 taagaataaa gaggtgaagg ggatgtccct taagcaaaag ttacaagagg atttgaaatc
    81121 ttcgatgaaa aacaaagata cagtgagaaa atctgtagta actttaataa gagcttctat
    81181 aaagcagtat gaggttgata atagggtcga gcttgatgaa gatggaatta tcgatgtaat
    81241 agcaaaacaa ttaaagcaac gtagagatgc attagttgaa tttgaaaaag ctggaagaga
    81301 agacttaata aaagaaacag aaggtgaaat tgaagtttta aaagagtacc tacctcaaca
    81361 attaagcgaa gaagagttag aagaaattgt aaaatctact atatctgaag taggggcaac
    81421 ttctatgaag gatatgggaa aaataatgtc agttatccaa ccaaaagtta aaggaagagc
    81481 tgacggaaaa cttataaata agttggtaaa acaaaactta caatagattg atatagccta
    81541 gagagaaatc tctaggcttt ttatagtttt tgggaataac gagtcatatt tgagcatatc
    81601 tataatcaaa gaaaattttg aaagaagggg aaaaatttga ttatatcagt aaaagagatt
    81661 aggaattttt tgataaacat atttatacca ctaataatag gttacttaag tagcatctta
    81721 acaatgatta tcagtggaac agatatttca acctattatt tacaactcac aaagccaagc
    81781 tttgcaccac cagcttttat ctttcctata gtttggacta tattgtacat attgatgggt
    81841 atatcttcat acctaatatt aagaaaaggt tacaacttac ctaaagtaag agatgcaatt
    81901 ttttattatg gattacaact tgtattaaac tttatttgga gtatactatt ttttggattt
    81961 ggacttagat ttacagcttt gatagatata ataataatga ttttggtttc tataataatg
    82021 atttcgaagt tttctaaaat agataagaga tctggataca taaatttgat ttatttaatg
    82081 tggcttgttt atgcaggatt tttgaactat tttatatggt ttattaataa atagaatgta
    82141 aagattttgt aaattaccct gtacttttaa taatatcata acaaacgaaa aataaataga
    82201 ctattaaaaa taatcatttt catatacaat aatattaatt taaatacaat aaatttataa
    82261 aaattgtatt taaagattaa catattaaag tattagaatt ggaaaggctt gaagggagag
    82321 gtttttatgc aaataatagt atctgggaga caaatgaaat taactgacgg aataaaagga
    82381 tacgtagatg gaaaattaag taggttagaa aaataccttg atcctgaatc agaagtgaaa
    82441 gtaacagtaa gtgcgaaaaa ggatagacaa aaagtggagg ttacaataat tcctattaac
    82501 ggtcaaataa taagagcaga agatgtagaa gatgacttat atgcagcaat tgatattgtt
    82561 tgtgacaaat taagtagaca agttgtcaaa tataaaacta aagttaaaga caaagttcaa
    82621 aataataaga gcataagatt tgaaaatctt gactttatag ataatagcag tgaatttgat
    82681 gattatgatt atgatgatga agaagatgaa aatatagtaa tagaaagaag aaagaaattt
    82741 aatgtaaaac ctatgagttc tgaggaggcg atacttcaaa tggaactagt aggacacaat
    82801 ttctatatgt ttagaaacca agataatttt gaaataaaca tagtgtataa gcgtaaagct
    82861 ggtggatatg gtttaataga acaagattaa taaaaattgt atacgtttag attttatata
    82921 agaaaaaata aaaaggtaat catgttgatt ttttatcaat atgattacct ttttcttgtt
    82981 taaataatat attagatatt aggtatttat tatataaaaa ttttaaaact aatctgttac
    83041 aacatcaata aagtgcataa atacctattt caagcataaa attaattaag ggggtaatgc
    83101 ttatgttaga aatatccact gatttacaag taaatcaacc agttattact gttacaagta
    83161 atacgtttat tagtatagaa aattatctat caatattaga atatgaagtt gatttaataa
    83221 gaataaagac taaagttaaa acaattaaaa tatctgggga taaactttca cttaagtata
    83281 ttactgatag tgagataggt ataaaaggga ttatctacaa tgttgagtat gttgattagg
    83341 aggagataca cttgataagt tttataaggg gatactatgt tatagttgtg gaaggagtag
    83401 gactcgaaca atttttaaat catcttataa gaaatgggat aagtgtttac aatgtaacta
    83461 gaataaaaaa tactaaaatg gagtttcata tagatagaca agatataaaa gactttaaga
    83521 atgtttatag aggaagtaag tttgatataa aggtaaagca aaaaactggg gtccctttta
    83581 ttatcaaaag agtttataag cacaaaggta tgtggatttg tgctcttgtt tctttatttt
    83641 tattgatgtc tacatcacag tttgtgacag atgtatatat acaatctcct gaaggtataa
    83701 aaaaagaagc tcttagaaat gagctttata aggttggagt aagaccagga gtctataaga
    83761 agagtattga tagaaaagaa gttagagacc atatgatgtc aaaatttaat gatgtggcat
    83821 atttatctat caatgtaaaa ggaacaaata tatttgttac tgttacaaaa aaggcagaat
    83881 ccctaaaatc tacagaccaa tcaaattatt gtaatgtaat tgctttaaaa aatggtataa
    83941 tagaaaaggt aatccctaga agtggtaaat cagttattaa atctggagac atagtccaaa
    84001 agggagatgt cttattaaat ggagctaata ccaagtcaat accagaagta tgggcaagta
    84061 ctttttatga gtccacaaaa aaggcaagtt atgtagatac tgtaaataaa aaaactggag
    84121 aaaagaaaaa tatatataca ctaagttttt atgataaaga gtttacaatg agaaaaaata
    84181 taaaatataa agattatgtt gttgaaaata aagaaaaaaa actatcaata ggaaactata
    84241 cttttccaat aaagataaaa acgagtactt tttatgaaac aaaaaaggtt gaagtaaaaa
    84301 ggaataaaga agagttaaaa aaagaattat ctgaaaaagc tttaaaagag ttagaataca
    84361 taatcccagc ttcggctaga ataatagatg taaaacataa ctttaaggtt aataaaaata
    84421 tgttagaata tttaataaca gttcaaacta gtgaaaatat tgctaaaatt tatcctctta
    84481 gtaagtcaga agcagaaagg tttataaagg aagaaagtaa accagatgaa ggtgaagagg
    84541 aagttccttc caatccagaa aaaagaccat taaatgatat aagaaatgag tttgatgagg
    84601 ataataagga taataaagat caaaacaatt ctgatgaaaa taatagtaat caaaatagta
    84661 ataatagtca aaataataat agcaataaca actaataaaa ttaaacttaa aatcttagga
    84721 ggactaattc aattgataat acaaaagaaa tttacaatag cagatggtaa ctttgaaaga
    84781 gagttatttg gcaactttga tgaaaatgta aaattaatag agaagacttt aaatatagat
    84841 gtaatactta gagaaggcaa tataatttta attggagaag aaaaaaatgt agattctgca
    84901 ttaaaactta tgaatgaatt acaccaaact gtatcaaatg gtaagcattt agataagcag
    84961 agtatttctt attcattatc tcttttgctt gaaggaagtg aacaaaaaat aaaagaactt
    85021 gaggggacaa tcgtcataac tcaaagggga aaagctgttc aacctaaaac tttaggtcaa
    85081 aaagaatata taaaacttat agaaaataat gatataactt ttggtgttgg acctgctgga
    85141 acaggaaaga cttatcttgc ggttgctatg gcagtaaaag cttttaaaag agatgaagtt
    85201 agtagaatta tacttacaag accagctgtg gaagcaggag agagtctagg ttttttacca
    85261 ggagatttaa aggacaaagt tgacccatat ttaagaccac tatatgatgc cttatttgaa
    85321 atgttgggtg ctgataaatt taataagtat ttagaaagag gtactattga ggttgcacca
    85381 cttgcattta tgagaggtag aacacttgat aattcattta taatattgga tgaagctcaa
    85441 aatactactt ctgaacaaat gaaaatgttt ttaactagac ttggatttgg ctctaaagct
    85501 gtagttacag gagatgtaac tcaaacagat ttaccacaaa ataagaagag tggtctaata
    85561 caagctacag agattcttaa aggtgttcca ggtattgggt ctataatgct aacagataga
    85621 gatgttgtaa gacatgagtt ggtacaaaga ataataagag cttatgagaa gcacgacaaa
    85681 agagaagaat ttaaaaaaga agaacgtaaa aaagcgaaaa tgcaggaaaa gactttcaaa
    85741 agaaagtaaa agtgtagtaa tatagatata tagcattatt aatgaataaa aagtaggtgt
    85801 agtgaatgga tttgatacta gatgatagac aagataaatt agaagtaagt gaggagttaa
    85861 ttgaaaagat aaaggatata atcatagaat gtttagatta tgaaggatat gatgataatt
    85921 atgaagtgag tctttctttt gtagataata aagagattca tgaattaaat agagaatata
    85981 gaggagttga tagagtgact gatgttttat catttcctct tttaagtgat gattttgagg
    86041 atgttgagtt agaagaagaa tccctaggtg acatagtagt atctcttgaa agagccttag
    86101 aacagagtat agagtataac catagctttg aaagagaagt atgtttttta atatgtcata
    86161 gtatgtttca tcttttaggt tatgaccacg atacagatga aaatacaaaa gaaatgagag
    86221 aaaaagaaga acacatatta aataagttaa acataacaag ggagtagttt ttatgaaacc
    86281 agaaaaaact cgtcaaggta taattaaagc atttaatgca gctatagaag ggatattgta
    86341 tacatttaaa tttgaaagaa atatgaaaat acattattta ggttcagttg ctgttcttat
    86401 aataagtttg ttttttaact tttcaaaatt agaaatgata atgttactta tgtccatatg
    86461 cttagttgta gttgctgaaa tgtttaatac agctatagaa aaagctgttg atttagtaac
    86521 tgatgaatat catgttcttg ctaagatagc aaaagatgtt gcagctggag gcgttctagt
    86581 ggcagcacta aattcagtag tagttggata tattttgttt tatgataaat tgacagatat
    86641 atctggaata ttaatttata aaataagaga atcagaatta catataacct tgatatgtat
    86701 attattggtt cttatagctg ttgtagttgt aaaagcattg acttctacag gtactcctct
    86761 aaaaggagga atgccaagtg gtcatgctgc cttagcattt gctatagcaa ctgcaattac
    86821 acttatgact gaaagagttg ttgcctctac tcttgcatat ataatggctg tattagttgc
    86881 ccaaagtaga attgaaggaa aaatacatac cttttgggag actattgctg gagctttgtt
    86941 aggtgtgttg atagctatat tagtatttca gcttggaatg ttctataatt aaaataaatg
    87001 tacataaaat atttaaaata aaacaaatct gtgctaatta aatttttatg atataatgta
    87061 gagtattaaa taaaaataac ttttaattat tgtatacagg aggagttgtt gtggataaca
    87121 tagaattgtt aaggttggca gaagatgcca gacaacattc ttatgctcct tactcaggtt
    87181 ttagagtagg tgcagctctt ttaactaaga gtggtaaagt ttatactgga tgtaatatag
    87241 aatgtgcatc attaggtgga acaaattgtg cagaaagaac agctattttt aaagcaatat
    87301 cagagggtga taaggatatc tataaaatag ctatagcaag tgataactca gaaaataatg
    87361 agcaaacata tccatgtgga atatgcaggc aggtaattat agagtttggt tctgatataa
    87421 aaataataac gggatatact aaaggagagg tgtttgagca tagtataaag gatttgttgc
    87481 caaactattt ctctggaaat gatttaaaat aaatttaaaa gtataaataa atttaagtaa
    87541 ttaaaacaag aagataaaaa gttaggagac agttaatgtt caaatcaggt tttgtcagta
    87601 tagtgggtag accaaatgta ggaaaatcta ctttaatgaa taatgtagtt ggagaaaaaa
    87661 tagctataat gagtgataag cctcaaacta caagaaatac aatacaagca gtatatacag
    87721 atgaagaaat gcagatagta ttcttagata caccaggtat tcacaaacca aaaaataaat
    87781 taggtgaatt tatggtaaag gcagcaacag aagcttttaa aaatgtagat ttaatattat
    87841 ttgtagttga tgattctaaa aaaataggtc ctggagatag aaagataata gaggatttaa
    87901 gaagtgttaa gacaccaata attttagttg taaacaaaat agaccaacta gaccaaaaag
    87961 atgagctatt tgatataatc aaaatgtatg atagagaagg catttttaaa gaaatagtac
    88021 caatatcagc attaaaagga aagaatacgg ataccttaat aaaagttata caaaattatt
    88081 tagaagaagg gccaaagtat tttccagatt atatgattac agaccagcca gaaagagtat
    88141 taatagcaga acttataaga gaaaaagttc ttcactatct taatgatgaa atacctcatg
    88201 gtgtagctgt tgaaattgaa aaaatgaaag cgagaaatga taaggaaata gtagatgtat
    88261 ctgctgtaat atactgtgaa agagattcac ataagggaat aataatagga aaaaatggta
    88321 ggaaactaaa aggaataggt aagtcagcaa gacaagatat agaattgctt ttaggttcac
    88381 aaataaatct tcaattatgg gttaaagtca aagaaaattg gagaaattta caaaattata
    88441 taaataattt tggatataat gataaataaa ggtgggttat atggatagga aactggatgc
    88501 ttcccaagat ttattatatg aagtaaaatc attaattgat aataataaag tattggagtt
    88561 aagagaatta atagaggaat atcatataat tgatatattc gatataatgg aaaatttaga
    88621 ggaagacatg aaaattcaat tatttgaagt acttccttta gatatggcat cttctatatt
    88681 agaagaaggt agtgtagagt tttttattag tattttatct aaactggatg tagaacactc
    88741 gaaaaatata cttgaactta tgtctcttgg agatatggca gacaagttga gtgaacttga
    88801 agaagaagaa agagaacaca taataaatct tttgaatcaa gagaatgccg attatgtaaa
    88861 agagttacta ttctatgatg aagattctgc tggtggaaca atgaccactg gatatatttc
    88921 tataaataaa gatatgacag ctcttgaggc tatagaccat atgagagaag aagctgaaga
    88981 agctgaaact atttattata tatatgtggt tgatgatgaa gaaaaactag ttggagtatt
    89041 gtcattaaga gaattaataa tagctagaga cgcaaatata gtagaagatt tgatgagtga
    89101 aaatataatc tctgtttatg tagatgaaga tagagaagaa gcagtaagat tagtatctaa
    89161 atacaattta atagcaattc cagtagtaga cagacaagaa aaattaaaag gaataataac
    89221 agtagatgat ataattgatg taatggaaga agaagcaact gaagatatgt ataaatttgc
    89281 aggaagttca gaacatgaaa gagaagttgc tgaaaaagaa aaccctacat tgagagagca
    89341 aataatatca gcacttagag gacgattacc ttggttaatt attaccttag ttggagggtt
    89401 gttggcttcg ttaatacttt ctaacttaga ctatataatg aatcctgtat atgctccatt
    89461 agtatttttt atacctgtag taattggtat gggtggaaat attggaactc aatcatcatc
    89521 tgttacagta ataacattat ctaataagga tttaaatttt agcaatgtgg ttagagaagg
    89581 tattgtaggt attattacag gtcttttgtg tagtataata acaggtattg taatttactt
    89641 tgttatgaga aagttagaca ttgtattaat tgtttcaata tcattattta taaatatggt
    89701 tttaggtgca acaataggtg cgtttatgcc tgttttatta aaaaaaatgg atgcagaccc
    89761 atctacagtt tcatcaccaa ttatatctac agctcttgat ataactggta tagcagttta
    89821 ctttataata acaacggcat tattgtcaaa aattgtttaa taactttatg tatgatttat
    89881 cctcttctta ctaaaaatat aagtataaat gtaagaaggg ggttttttaa aaatgaacaa
    89941 tatcagttgg gaagttttta aaaaaacagg tagtatagat gcatatttat atttctgtga
    90001 ttgcaaaaac atacatgaag aaattgaaga agtaagggag aaaaaagaag acgatgataa
    90061 tcctgaacac ccaggggata gtacttaaag ctataaggta taaggaaagt gatataatac
    90121 ttacactatt tacaagaaag cttggaaaag tatctgcaat agcaaaagga gctaaaaaaa
    90181 ataagagctc tttgctttca tcatcacagt tattttctta tagcaatttt accttaaaaa
    90241 aacaaggtaa tatgtacaag gttactcaaa gtgaaataat aaaaagtttt tataatatat
    90301 cctatgatat agaggcattt tcttatgcta catatattac aaaattagtt gaaaattcta
    90361 tacttgaaaa tcagactaat aataggctat ttatattact tgcgcagact ctgtatttgt
    90421 atacacagga taatacagac aataggttta taacagcagc attcgagtta aaatttttag
    90481 actatatagg atttaaacct atagtaaata aatgcattaa ttgtgaatgt aaaattttac
    90541 aaaattctgt gtttaatatc tacgaaggtg gtatactatg tagtaagtgt agtaaacttt
    90601 ttgataataa tataaaatta gacttaacaa ctataagtct tatggaatat gtattaagaa
    90661 atgatatttt aacatgtagt aaagctaaag tatcaaaata tataacacat gaacttgaga
    90721 atattctaga caagtatttg aaagtttatg ttgataatat taattttaaa tcattacacg
    90781 tattgcaaag tgtaaaaaat aataagggag tggataatga tgagtagtaa tataactatt
    90841 gaaatggttg attcagtctt tgaaagagtt ccaggagcaa cttatgcaga agcaaaagaa
    90901 gcattagtaa tgtgcaatgg agatgtaatt gaggcagtaa tatatttaga aaataaaaaa
    90961 aatacttgta attgtaaagc aaaatctgct aaagaaacta tggaagaagt atttggcaaa
    91021 gatggagaaa atataaagtt tcaattaaaa gagcttctta gaaaaagtag tgtagtgaga
    91081 ataatagttg aaaaagatgg aaaaactatg atgaatattc ctttaacagt tggagttgtt
    91141 ggattagctt ttgtaccatt agctacttta gttggattat cagctgctgt tataagtaaa
    91201 tatcgtataa aagttcaaaa tgaagaagat ggagaaattg tagatttagg tgaattgaat
    91261 gaagaaaaac ttcacgtttt gaagaatatg ataactaatg cagcaaaaga tgtgaaggat
    91321 gtagtagttg acaaaaaaga agatgacaaa gatgtaactg ctgaccttat gaaagaagaa
    91381 tctgaaaaga ataaagaaga cgaagacgaa aataaataga tataaagtga cttttaaaaa
    91441 atgaagagaa gataattata agaattatca ctaacattga caaattttat agaatttgat
    91501 attctaaaag ttgtagaaga actattaaaa tagcctttcg tgtagacgag aggctttatt
    91561 gttataggag ggatttttat gaattttcaa gagatgatac tggcgttgca aaaatactgg
    91621 tcaaagcaag gttgtatcat gatgcagcct tatgatattg aaaaaggtgc aggaactatg
    91681 aatcctaata cttttttaag atcattagga cctgagcctt ggcaagtatg ctatgtagag
    91741 ccttcaagaa gaccagcaga tggaagatat ggtgaaaacc caaacagact atatcaacat
    91801 catcaattcc aagttatact aaaaccttct ccagataata tacaagaatt atatttggaa
    91861 agtttaaaag agattggaat tgacccaagt gagcatgaca taagatttgt tgaagataac
    91921 tgggaagctg ctacagttgg tgcttgggga cttggatggg aagtttggct agatggtatg
    91981 gaaataactc aatttacgta ttttcaacaa gtaggtaata ttgaatgtga gcttgagaca
    92041 ggagaaatta catatggatt agaaagatta gctatgtaca ttcaagaagt tgatagtgtt
    92101 tatgatttaa aatggaatga taaaataact tatggtgaag tatttaataa agctgagtat
    92161 gaaaactcaa tgtacgcatt tgaattatgt gatgcagata tgttgtttaa tctgtttgat
    92221 atatatgaaa aagaagcatt aagacttatg gaaaatggcc ttgtaatacc ttcatatgac
    92281 tatgtgttaa aatgctctca tgcatttaat acattggatg caagaggtgc aataggagtt
    92341 agtcaaagag cttcatttat aggtagagtt agaaatatgg caaagactgt tgcagaaact
    92401 tttgtaaaac aaagagaaga aatgggattc cctcttttaa aggacggtga caaataatga
    92461 aaaattatct tttatttgaa atcggtgttg aagaaatgcc atcaagattt gtaggcagta
    92521 cactagaaca attaaaaaac aatcttagta aattatttga tgaaaataga atagcttttg
    92581 ataaaataaa tgcgtatggg acaccaagaa gacttacttt agtagtcgaa ggattgagtg
    92641 atagacaaaa tgatttagaa gaggaaataa agggtcctgc taagaaaatt gctgttgatg
    92701 cagaaaataa tttaacaaaa ccagcattag gatttataaa aagcaaagga ttaagcgaat
    92761 ctgacatata ttttaaacaa gttggaaaag aagaatatat atttgcgact ataaagcaag
    92821 atggaaaaga aacttcagaa gtactaaaag acatattacc agagactata aaatctgtag
    92881 tattcccaaa agctatgcgt tggggaggaa aaaatcttaa atttgcaaga cctataagat
    92941 ggatagttgc attgttaaat gataaagtat tagagtttga tttagaagga ataatatctt
    93001 ctaatgtaac aaaaggtcat agatttttag gtgaaagtac aatagaagtt gattctatag
    93061 aagattattt tgaaaaatta gaaaaaaatt atatagtttt agaccaaaac aagagaaaag
    93121 aaatgataag aaaacaatgt atagaagtag caaattcttt aggtggagaa gttgaatttg
    93181 atgaagattt acttgaagag gtaacttatt tagttgaata tccaactgct ttttatggag
    93241 aatttgatgt ggattatata aaactaccaa aagaagttgt tataactcct atgaaacaac
    93301 atcaaagata ttttccagta cttaaagaag gaaaactgtt acctaacttt atagctgtta
    93361 gaaatggtga ttcttacaga atagacaatg ttaaagctgg aaatgaaaaa gttttagaag
    93421 caagacttgc agatgcttta tttttctata gagaagatac taagagaaac ttagaaagct
    93481 acatagaaaa attaaaaact gttgtattcc aagtaaaact aggaactatt tacgacaaaa
    93541 ctttaagact tgaaaaatta agtgctgata tacttgatag tttaggttta gtagatgaaa
    93601 aggcagatac tataagggct gctaaattat ctaaggcaga tttagttact ggaatggtag
    93661 gagaatttga tgaattacaa ggttttatgg gaaaagaata cgcaaaagtt ggaggagaga
    93721 atgatgttgt aagtgaagct atttttgaac attatcttcc aagatttgca ggagatatac
    93781 ttcctaagac taatgcagga gttgccttat caatagctga taagttggat tcaatagcag
    93841 gtttctttgc tataggaata caaccaacag gttctcaaga cccatatgct ttaagaagac
    93901 aagctttagg tatacttagt atacttatgg acagaaaagt tgctgtggat ataaaagtac
    93961 ttattgaaca tgctttagac aattattctg aattagattt tgataaagaa gaagttgttg
    94021 agcaaataat gaatttcttc aatgagagag taaaaaatct atttaaagat ttaggaataa
    94081 gatatgatgt tgttgatgct gttttaagtt ctgatataaa tgatgtttct gatatgcata
    94141 tgagagcttt agagcttaat aattggctag aaaaagatga attagtggag atgcttactg
    94201 catttaatag agtttctact ctagctcaaa aagcagaaag tgataaaatt gatgaatctt
    94261 tattaaaaga agatgctgaa attaaacttt acaatgaatt taaacaagta aagataaaag
    94321 ttaatgaatt attaaaggat aagaaatatg gtattgcttt agatgaattt gcatctttaa
    94381 gaccagtagt tgataattta tttgatacag ttatggttat ggataatgat gaagctatta
    94441 agaacaatag acttgcttta cttaaacaag tatatgatac tatgctagaa atttgtgatt
    94501 tatctaaaat tgtttataaa taaaatttaa actatttata agaaataagg ctgtctcaaa
    94561 atagagatag tcttattttt cattgttgag atgatgaaaa tatatttgat ttcatagaaa
    94621 aagagtgtct cataaactaa aaagttcatt ttgagacacc catgtttttt gtaagtaaat
    94681 ataataaact atattttata cttatcagtt attttgttta aaatattatc atttgaattt
    94741 acccattcat aaaaattgcc tgatgatgcg tccgatattt tataaagcat ttcaggaata
    94801 tcactagctt taaaatctcc aagtgatttt cccaatctag tcttacctat ttcaaaactg
    94861 cctccaacaa ataattcaaa tgtatctgta gatataccat caacattctt ctttttacca
    94921 cataaaccta tgctaccaac ttgatgaaca ccacatgaat ttaaacatcc tgatatatat
    94981 aacttaggtg ctttatttaa aatttcttca ttattttgta atctaaaata atctatgatt
    95041 tcatgtaaca ttttctgact attttgtatg cccatttgac aaattggaac acctatgcaa
    95101 gatatacttt gttctaattg agaattacaa ctaatagttt tacttatttc taatattctt
    95161 tttgcttcat ttccatttaa atttaaaata tataatccct ctgtcattcc tagtctaatc
    95221 ataggatttt caacattatc taattcttta agtaaagtac ttaaatcctt tgttaacaaa
    95281 atacctccaa ctggatgtat atatacagtg tataaaccat cctgtttttg aggtattagt
    95341 ctagaatctt gtatatctat tttaactcca ggtttagagt aatctatttc ttcaatattg
    95401 agttcaagac taccattttc tttttctaat ttatagtatt ctttaaattt ttctaagaat
    95461 agttcttcac caagtgattc gaccatatat ctaaccctag ctctgttttt attttcataa
    95521 tttccataat ccataaagaa tttaatcata ccttcaacac aatataaggc atctttcggc
    95581 tttataagtt catcaagttc taaagcaact ttgggttgtt tacctagacc tccacctaag
    95641 aaaactctga aatatggttc atcatttttc aaagtagcaa caaatcctaa gtcttgtata
    95701 ctacaatgag cagtatctgt gtaacaatta gaataagaaa cttttaattt tctaggtaaa
    95761 tggtatgtag tagcattttt gataaaatat ttatcagtag caactgcata tggagtaaca
    95821 tcaaagactt cactagggtc aactccagat aatggagata atccgacatt tctaggataa
    95881 ttaccaccac cacctctagt gaatatatca ttttttattc cttcttccat gatatcaaca
    95941 attgaattta tagataaatc gtgcaattgt atagcttgtc tagttgttaa gtgtatctta
    96001 tctaagttgt gtttaatagc tatttcatag attttattaa gttgatactg agataaaact
    96061 ccagcagata ctctaagtct tatcataaaa gattttttgt ctctttgagc ataaacacca
    96121 tatccaccag aaaatccctt atattgcatt ttatttattt ctccatttaa aaattttgaa
    96181 gaatattctt taaaattagg tagttcattt aacaatatct ttttaaaatt atccattatt
    96241 tcacctcatt gttagtcttg tataaaaata tatctattgt ataatagata tatatattat
    96301 tgtctagtca ggataaaaat ataacagaat aattctatta aaagtaagaa taataaggac
    96361 atagtgagta ttttgttttt attttacaaa ttaagtataa tatttttgtt ttataaaata
    96421 taattaagat aaatagataa ttttgtaatt ttaatatata atatttagta gagtgtggga
    96481 gtagcactta atatttgcag gaggagtttt tgtatatggg agaaataata aatgcattag
    96541 atagagccct agacataatt ttgctgttat atcatgaaaa gagagaaatg ggaataactg
    96601 aaataagtaa ggctatggga gtatataaaa gtactgtaca tagaactttg gttactcttg
    96661 aaaacaaagg ttttgttata caaaatgcag agaatggtaa gtattggcta ggaataaatt
    96721 tatatgcaat aggtatggtt gtgggagaaa aaatgtcatt gactgaaata gtaaaaccat
    96781 atacgaaaaa attaaatcaa gaatttaacg aagtagttaa tgtatctata ttagaagaaa
    96841 gagctcaaga ttctccaaga agtatcataa tacataaaga gtatggttca aatcaattac
    96901 tttcagtaaa tccatccgtt ggttcaagta gtgaatgtta ttgttcagca gttggtaaat
    96961 gtcttatggc atttaatgat tctatagatt ttgaaaaata tagaaaaaca ccaatacaca
    97021 agtatacaga acatacaatt gataattggg atgatatgat gcttttttta gcaaaaataa
    97081 aagaacaagg atatgctata gatgatgaag aactagaaca tggactaact tgtattggag
    97141 cacctatctt agataaaaat aataaagcta ttgcagccat aagtttgtca ggtccaacta
    97201 taagaatgag agaaggggac tttgagtata agattaaaag agttatagaa actgcaaaaa
    97261 gtatatctga actttttaga tgatttttaa tctcgataat aaaaataggc tatatttaaa
    97321 ttgttatttg taaatatcag tttaaatgta gcctattttt ctttaatcta aaattaaata
    97381 ttcttaaaat ttaaaatgtt attgaaatat ataagcgaat gtgttatctt ttaattaagc
    97441 aataaaaata gaacaaggtt ctatactata gaacaaaatt gatgcatata tagtatttat
    97501 acaaaatata aatattatat atttaaaatt aagtaaaaat attacataaa ggggagattt
    97561 gagaaatgga aaaagtcaag ttgagtgttg aaagatgtaa gggatgctat ctttgtattg
    97621 aagcttgtaa aaaagatgca ataagtcttt ctgactacac aaataaaaaa ggctttgtaa
    97681 ctattaaagt cgacgaagaa aaatgtattc aatgtggcgc ttgttataca atgtgccctg
    97741 atttagtatt tgagatatta taaattattt ttattagagg ggagaaaagg tatgcaaagt
    97801 ttattaatta aaggaaatga agctttagca gaaggtgcta tacgtggtgg ctgcagattt
    97861 tatgcaggtt atccaataac accacaatca gaaatattag aaatgatggc atggagacaa
    97921 aaagaagttg gaggagtatt tatccaaggt gaatcagaaa tagccagtgt aaatatggtt
    97981 atgggagcaa gtgcacttgg agcaagagct atgacttctt catctggtcc aggattttca
    98041 ttaaaacaag aaggtattgc atattgggta tcagctggtt tgccagcagt tgtagcatgt
    98101 gtgcaaagat atggtatagg tgatggattt ataggagctg gtcaagataa ttattggcaa
    98161 gcagtaaaag gcggtggaaa tggagattat catttaatcg tgttagcacc taatagtgtt
    98221 caagaaaata tggatatggc atatgaatct tttgaattgg ctgaaaaata tatgcatcca
    98281 gtacttatac tttctgatgc tacaataggt caaatggtag aaccttgtat agcaccacca
    98341 atgaaagaat acgatatgga taaagctcca tgggctgcaa aaggaacacc tgtaggagaa
    98401 aaaaataaag taataactga tataacatat tttgaagacc aagatacatg gcaaaaaggg
    98461 tatatagaaa aaatgagaaa agttcaagaa gatgaacaaa gatgggaaga gatagaaata
    98521 gaagatgctg aagtggtatt tgtggcatac ggtatttcat caagaatagc agaaggtgca
    98581 gttagagatg ctagagcaaa aggaatgaaa ttaggtctaa taagaccaaa aacattgtgg
    98641 ccttacccaa gaaaagcatt taagaaatta agtgattcat tgaagggact tgtaacagtt
    98701 gaaatgaaca tgatggcaca gatgaaggaa gatgtaatta tagcatgtga taatagattt
    98761 ccagtatatt cagtagcaac agctcaatat atggcagaag taaatcaatt aatagatttt
    98821 gctcaacaga ttatagatgg aaaagctaag caagaggagg tattttaatt atggctaaaa
    98881 aagcaccagc aataatgatg tgtgaaaata tgttctgtgg aggctgtgga cactctatag
    98941 tcgatagaat tattggagaa gtattaacag aaatggatat atgtcaagat acaattatat
    99001 gttcagatat aggttgtaat catatgtttc aatttagtat gaatgtagat gttgtcgttc
    99061 cacctcatgg taaaatggga gcagcaatgg cagctatgaa aagagttaga ccagataaat
    99121 atatatttac aatagctgga gatggtggag cttatgcaat agggcttgga gaaactatgt
    99181 cagctgctac tagaaatgat aatgtaatat ttcttgttat gaacaataat atgtttgcaa
    99241 tgacaggagg gcaaatggct ccaactacta tagaaggtca atatacagct tctactccag
    99301 cgggtagaaa ttacgcagat catggttcaa catttgatgt tgtaaaagtt atgggaaatt
    99361 tagatatagc atatctagca agaggaacaa taactaaccc taaagaaata aatacaacaa
    99421 aaagatacat caaaaaagct ctagaaaaac aaaaagaaaa gaaaggtttt tgcttaatag
    99481 aagtgcttgt accatgtcca acaaactggg gattaaagcc agtagatgct atgaagagaa
    99541 ttgaaaatga acttgttcca aagtatccac ttggagaatt tattgattag ggaggaaata
    99601 atatgttgaa tgaaattata tgtgctggtt ttggaggaca gggagttctt acagcaggaa
    99661 aaattataat gtatgttgca tataaggcag aaaagaaaat tacatggttc ccatcttatg
    99721 gaaatgagat gaggggagga agtgcaaatt gcaatgttgt tgtaagtgat gaaaaaattg
    99781 caaatccttg tgtaaaaaat ccagatatac tattgggaat gaacagcgta tcagtagata
    99841 agtatgaaag tttaatgaaa aaaaatggtt atatgtttgt caatgaatca ctagtaagta
    99901 aggatagaaa gtacagagaa gacattaatg ttataaaagt acctgttact gaaatagcac
    99961 aaaatttagg caatgaaaaa gctgctaaca tttgcatgtt aggtgctatg gtaaagagtt
   100021 tggatttatt tacaaaagaa gaatttgaaa gtggtatgtg tgaatacttt gaaaatcaag
   100081 gcaaaggtaa attcaattct aaaaatgtag aagcatttga agctggatac gactacgaat
   100141 gaatatttta aatatttaaa ataattattg aaatacttat ttttatatgt tagtatttaa
   100201 ttaataaaat atagaacgtc gttctggaca atgggacaaa gtctttaggt cggaatacaa
   100261 gaacgacgtt ctgcatagta gaactagggg gtgttaaatt gaaagtttta gtaataaatc
   100321 ctggtggtac atccacaaaa atttctgttt tccaagatga aaatgaaatt ttgaaaaaaa
   100381 atataaccca tacaagagaa gatttaaaaa atttttctaa agtatttgat gaatatgatt
   100441 atagaaaaca actgatagta gatattttaa gtagtgagaa tcatagtata aattcttttg
   100501 acgcagtagt tggtcgtggt ggacttatga aggctataaa aggtggtacc tatactgtga
   100561 gtgaagaaat gattgaggat atgagaaatg aaataaatgg ggaacatgca tcaaatttag
   100621 gtgcattatt agctaaaact atagctgatg aaataggagt acaatcattt gtagtagacc
   100681 cagtttctgt agatgaattt gatgatgtat cgaggattac aggaatatca gacatagaaa
   100741 aagcaagttg gttacatgca ttaaaccata aagctgtttc aagaaaaatt gcacaaaaac
   100801 tagggggaaa atacgaggat tataacttta ttgtagctca tttaggttca ggaatatcga
   100861 ttgtagcaca taaacaaggc aaaatgattg atggaagtgg tggtaggtct gatggtccat
   100921 tttctccaga aaggagtggt ggattacttg catatcctct tatagaattg tgttactccg
   100981 gaaaatatac tcatgatgaa atggtcgcaa aagtaagttc gattggggga atgtacgatt
   101041 atttaggaac aaaggacatg atagaaattg aaaacagaat caaggatggt gatgaaaagg
   101101 caaaacttat aatggatgca tttatttatc aagtagcaaa agaaatttct atgtatggag
   101161 cttcactttc agggaatgta gatagagtta tcttgacagg agggatatct cactcagaaa
   101221 tggtagtcaa aggagtagca gaaaaagttt catatctagc tccaatagag atagtaccag
   101281 gagagatgga aatggaggca cttgctctag gggcacttag agtacttaat ggagaagaaa
   101341 tagcaaaaac ttattaatat ttaggagaaa gagtatgtta aaagatttta ataatttatt
   101401 agaagaggct aaaaagcttg aacctgttat tgtaagtgtt gctgttgcag aagacaaaga
   101461 agtattaaag gctgtgaaat cagcaacaga tttaaacatt ataaagccaa ttcttgtagg
   101521 agacaaggat aaaatagaaa gtatatcaag agaaattgga ttaaaaggtc atgaaataat
   101581 aggttgtcaa aatcccgatg aatcagttaa aaaagctgta gagatagtta aaaataagga
   101641 agctaaagtt cttatgaagg gattagtaaa tacaagtgtc tatatgagag ctatattaaa
   101701 taaagaaacg ggtcttagaa caggaagatt attaagtttg cttgcagtat atgaattacc
   101761 tcaatatcat aaacttcttt attgtactga tagtggaata aatgtatcgc caaacttaaa
   101821 tcaaaaaaaa gatataatga caaatgcact tcttactatg aaaagtatag gcatggaaaa
   101881 tcctaaaact gcgatactta ctgcaaatga aatggtagac cctaagatac aatctacagt
   101941 ggatgccaac ctacttgtag agatggaaaa atcgggagaa ataccaaagt gtatagtgga
   102001 aggtccaata gcatttgatg tagcatttga tgcacatgca gcagaacata aaggtattaa
   102061 aagtaatatt gctggtgatg ttgatttatt agtatttcca aatatagaag cagggaatat
   102121 attaggaaag tcatggctta gatttaataa agctaagtgg gcaggtatag ttttaggagc
   102181 aacaaatccg ataattttag gttcacgttc tgacacagct gaaataaaaa taaattcaat
   102241 agcattagcg tgcctagcat cacaataaga aattattatt aaggaggaaa aagtattatg
   102301 aaatatgcaa aaagaatgga tatggtaaaa gcttcagcta taagagattc tcaaaagaaa
   102361 atagctcaga aggtagcaag tggtggaact gttatatctt ttgctgcagg gcttcctgac
   102421 ccaaatttat ttccaataga agagataagt gaaataactc aaaaagtact taatgaaagg
   102481 ggaaaatttg ccctagcata tggacctact aaaggtgaag atgagttgtt agatctatta
   102541 gtaaaaagaa tgaaagaaga agaaaatatt gatacaaaag cagaaaatat tataataact
   102601 actgggtcac aacaagggat agcattaagt gctatgattt tattagaaaa gggagatgta
   102661 gtagttacag aaaatccaag ttacttaggt gcaataaatg catttagacc ttatgaatgt
   102721 gattttttag gagtagatac agatgaagaa ggaatggtaa cagatgattt agacaaatta
   102781 ttatctgaaa attctaacat aaaggtgata tatgtaatac caacatttca aaaccctaca
   102841 ggaaaaacat ggtctttaca aagaagaaaa gattttatgg aagtcgtgaa caaatatgat
   102901 gtcatagtaa tagaggataa tccttatgga gaaataagat ttacaccaga acctctacct
   102961 acacttaaat ctcttgatac taaagataaa gtattgtacc ttgggtcatt ttcaaaggta
   103021 ttatgtccag gatttagagt tgcttggatg tgtggtaatg tagacatcat agataaggca
   103081 gaacttttaa aacaaggtat agatttacag tcaaatcaat tttcgcaagt acaagtaata
   103141 gaatttttaa agaaatacaa cttaaatgaa catatagaaa aaataagagc agagtataag
   103201 aaaagatgtc tgctaatgtt agatgctatg aagaaacatt tcccagagga agctaaatat
   103261 acagaaccag atggaggaat gtttatatgg gttgaacttc ctgaaagtat aaatgtagat
   103321 gatttattag ataaagccat tgatgctgga gttgcttatg tttctggaga gtccttcttt
   103381 gcaaataatg gtccaaaaaa tactatgaga cttaactata caacaatgtc agaagaacaa
   103441 atcgttaaag gtgttgagat acttgcagaa gttataaaaa aagaactcaa ttatgcttgt
   103501 gaataaatat aaaaagtgag ggtttaaata tgggagaaaa agaaaacggt ataaagtttg
   103561 gaaagttaat gtttcaactt gttattatag caatatcttg ggaattagtt tatattatac
   103621 catttatcca atatacatta tatgatccaa tcctaaaagc attagaatgt acaaacactc
   103681 aactaggttt tctacttaca atttatgggt taggtaatat atttggagct cctataggag
   103741 gctggttagc agatagattt gattatagaa agataatttt aggttctgta tttcttaatg
   103801 gagtagtatc atttttattt gcatttaata tgaactatcc atttgcagtt gctacttggg
   103861 taggttgtgc aatcacatca ttagttatga actatccttc tatggtaaaa atacttagag
   103921 ttataggaaa agataatcaa ggtaaggttt atggatttaa tgaagctatg gttggagttt
   103981 ctggagtagt aatgggagca atattcttat atatttatac atgctttgca actcctacat
   104041 tgggtatgag atgggtaatg atatctttag gaatattatc aatagcaatg tgtccagtat
   104101 tatggtttgt aattaaagat gtagatatta aagaagaaag agaagaagca ggtgaaaaaa
   104161 tgtctgctgg tgattttata acagtactaa aatcaccaaa tacttggcta gtaggaataa
   104221 gtatattctg tgtatattca ttcacagtta caatgtctta ttttacacca tatataacat
   104281 ctgtacttgg aggttctgta gcattatctg gtgcattagc aataataaga cagcatggtc
   104341 taaaattatt tggagcacca tttggaggat attgtgcaga caaattaaaa tctcctacaa
   104401 aagtactttt accaatatat gtatttggta tagcagtaat agttttattc ctagtattac
   104461 ctgcatcaac tccaatgact atattcatag ctttaacatt tgtagtaggt atattaggtt
   104521 acatgggaaa aggtatatat tatgcagtac aagatgaagt aaaagttcca gttaaatatt
   104581 cagcaactac tataggtata gctgcagctt taggattttc accagatgta ttccaatttg
   104641 cattaatagg acactggata gatacttatg gcaataaagg ttacacatat acatttatat
   104701 tccaaatagc aattctagtt attggaatac tatcttgttt atatatatta aaggttaaaa
   104761 agagaagagc aagtaaatta gaagcttaaa tattcaattt ggtaattaag tatatataaa
   104821 tacaatactt attttgatga atgtgattgt ataaataaca taaaaaatat caatagatta
   104881 agttttataa taatgtttag agaataaagt ataaaaatca aaatgttatc aagttttcta
   104941 ggttttaaca taaagttacc cctgaaggtg taaaattgag tggcaattat tatctatttt
   105001 cttacctaca taaacctatt taatttaaat tctaagagat tttcaaaata gatggtagtt
   105061 gtactcaatt ttaaacctca taataaatac gaaaatttaa aatctaacta gatactattt
   105121 aat
//
LOCUS       DAMKNB010000006        86359 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.006, whole genome shotgun sequence.
ACCESSION   DAMKNB010000006 DAMKNB010000000
VERSION     DAMKNB010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 86359)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 86359)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..86359
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.006"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            39..155
                     /gene="rrf"
                     /locus_tag="PC494_000486"
     rRNA            39..155
                     /gene="rrf"
                     /locus_tag="PC494_000486"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
     gene            275..466
                     /locus_tag="PC494_000487"
     CDS             275..466
                     /locus_tag="PC494_000487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF378 domain-containing protein"
                     /protein_id="HDF3911015.1"
                     /translation="MKKVALILAIIGALNWGAIGILGTDLIGSIFGGTYEMVSRIIYF
                     IVGLAGLYLIPSLMSDDRE"
     gene            621..2030
                     /locus_tag="PC494_000488"
     CDS             621..2030
                     /locus_tag="PC494_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HDF3911016.1"
                     /translation="MFIINELNKIVNEEVISFHMPGHKKGQVYKKLGYKDILKNLYKM
                     DTTEILGTDNLHFPEGIIKNSQKKASRVFKSDYTCYLVNGSSCGIQSAIMSVCSPKSK
                     IITNRDCHQSVINGCILGDIDIEYVPCEISEETNVLKGISISNVIDIIDKNLDAKAVL
                     LTYPTYYGMTYDLEYICNYAHSKKMVVIVDEAHGAHLGLSERLPKTALEQGADIVVQS
                     THKTLPAFTQSSMIHIQGDRVDIDKILNMLRITESSSPSYLLLSSLELAVDIYENKGK
                     ELMEELLNNIITFKNKVDSNINIYDTNDKTKIFISSKNMGLTGYELENILRNKYNIQV
                     ELSNYYGVLLICTIGNTVEDFSSLETALNNIVKEDFKFEKLENKKYPVVIPKKILTPR
                     EAFYKTKKSVKIYDSIGKVCGECIVPYPPGISVISPGEVISKEIIDYLMFCHSKGMIV
                     SGLKDVDLNFIQIIDLEDI"
     gene            2161..2850
                     /locus_tag="PC494_000489"
     CDS             2161..2850
                     /locus_tag="PC494_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate kinase"
                     /protein_id="HDF3911017.1"
                     /translation="MKGKLIIIESGSDASGKATQTEILYERLKKEGYMIKKVEYPNYE
                     SPSSALVKMYLKGDFGKNASDVDPYIASTFFTADRYASFKTDWEEFYNEGGIIIADRY
                     TTSNMVHQASKMDICDREEYLNWLADYEFNLFKIPQPDCVIFLDVPIEFSKKLMENRK
                     NKITGEEKKDIHESDIEYLEKSYNNALYIADKYDWKKINCVLDNKLRSIESIHNEIYK
                     IVLDSIKPMER"
     gene            2853..3788
                     /locus_tag="PC494_000490"
     CDS             2853..3788
                     /locus_tag="PC494_000490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HDF3911018.1"
                     /translation="MYFENIIGQDFAKKYLTNSIKKNKLNNAYMFEGMDGIGKKKFAD
                     ELSKLLLDYENLENSPDYVLIKPDGNSIKIAQIRNLQSDIVIRPHKDYKIYIINNAEK
                     MTVEAQNALLKTLEEPPNYAIIILVTNNKESLLETIKSRCDIIKFSPIPIEDLKRYLI
                     NTGIEEERAQLLAIFSRGSIENALNLSQSSEFSMMREDIQQYIQIMLDKNIVEILNIP
                     NNMEKYRGKIIALLDMMINYFRDIILLKENVNKNMLINVDKLVFIQNMSGKISYSQLS
                     KIIDIIEDAKSKIKSNCNFNISIQVMSLNIYEVIK"
     gene            3785..4678
                     /locus_tag="PC494_000491"
     CDS             3785..4678
                     /locus_tag="PC494_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage 0 sporulation family protein"
                     /protein_id="HDF3911019.1"
                     /translation="MIKIVGIRFKSAGKIYYFDPVDFNIEQDMDVVVETARGLEYGKV
                     VVGPKDMDESELVSPLKPIIRIATEEDKKVYLENKEKAKETFELCQQKIKEHELTMFL
                     IDCEYTFDRNKLIFYFTAEGRIDFRELVKDLAAIFKTRIELRQIGVRDEAKSIGGLGP
                     CGRKLCCSSWLGDFQPVSIKMAKDQSLSLNPTKISGICGRLFCCLKYEHDVYSEAIEK
                     MPVVGALVQSDDGKGKVVEVNPLLEQIKVEFQDKTVKIYTREDIKILREPKKCDGCGG
                     KCKDNDGLDEATLRELKKLED"
     gene            4756..5502
                     /locus_tag="PC494_000492"
     CDS             4756..5502
                     /locus_tag="PC494_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HDF3911020.1"
                     /translation="MQLKDSERIDDLQLKGLKIIQDTNGFCFGIDAVLLANFTKIKKD
                     AKVVDLGTGTGIIPILIAGKSEAKKIIGVEIQEDVYEMATRSIKLNGLEERVEIINED
                     IKYIDKVLDINGYHVVTSNPPYMHIDGIKNPNDKKAISRHEVRCNLEDVIRAASRLVM
                     PRGKFFMIHRPTRLVDIITLGRKYKLEPKVIQFVHPRPQKAPNLVLVQFVKDGRPELK
                     ILDPLYVYGEDGNYTKELKAIYNNKDIGEL"
     gene            5503..6336
                     /gene="rsmI"
                     /locus_tag="PC494_000493"
     CDS             5503..6336
                     /gene="rsmI"
                     /locus_tag="PC494_000493"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HDF3911021.1"
                     /translation="MSGKLYICPTPIGNLEDITYRTLRTLKEVDLIAAEDTRHSIKLL
                     NHFEISKPLTSYHEHNKDSKGDYLINKLIDGENIALISDAGMPGISDPGEEIIKQAIQ
                     NNIEIEVLPGATAFVTALVGSGMDTHRFVFEGFLDRDKKVRKAQLEELKEESRTIIFY
                     ESPHRLKDTLKDMLKILGNRNISINRELTKKYQEIIRENIETTIKIFEEKEVRGEFVL
                     IVEGFHGEKSKKENYDGLTDREYVLKLIESGMNKKDAIKIVCKDRKLKKDVVYKQVLD
                     L"
     gene            6359..7063
                     /locus_tag="PC494_000494"
     CDS             6359..7063
                     /locus_tag="PC494_000494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HDIG domain-containing protein"
                     /protein_id="HDF3911022.1"
                     /translation="MEIGKIIIESLKREDTHKIFIELDNKHELEKIIPKISCMKSVGE
                     CKYHVVNCFEHSINALKELEIVLNDKDFFPIHLRKHVSNYLNTYIEEGINKLHVLKLG
                     TFLHDIGKPDSMTLDETGRVHFTNHEKIGAQIIDNMGIKLELSTETYRLISKYVRYHM
                     ILLSLYKKNDLSRKELINVFNLVDEDTIGVIMLGYADIVSTVKLLGKSGEVSVLKTYM
                     EYILTNYLYKSNYTHV"
     gene            complement(7251..7679)
                     /locus_tag="PC494_000495"
     CDS             complement(7251..7679)
                     /locus_tag="PC494_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007287587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Lrp/AsnC family transcriptional regulator"
                     /protein_id="HDF3911023.1"
                     /translation="MDVTDYRIIEILQDDGRISMKDLGKIVGLTSPAVSERVKRLEES
                     GVIEGYKAIVNPDSLGRVIKAFIHISLPSNGYTEFIESAAKDPRIVECHHITGDDCLL
                     LKVIVKDMYELENVIDTIKKIGSTKTSVILSTPIQAKSIL"
     gene            complement(7716..9146)
                     /locus_tag="PC494_000496"
     CDS             complement(7716..9146)
                     /locus_tag="PC494_000496"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HDF3911024.1"
                     /translation="MRNLTLLTDLYQLTMLNGYFEKNIHEDIVVFDMFFRKNACDGGY
                     TIVCGIDQVVEYIDNLHFSDEDLEYLKNLNLFSDKFLKFLKEFKFTGDIYAVEEGTIM
                     FPNEPLITVKAPLYQAQLIETALLTIVNFQSLIATKASRVCFAAQGDPVFEFGLRRAQ
                     GPDAGIYGARAAVVGGCAGTANVLAGKMFDIPIIGTQAHSWVQKFDNELEAFQAYADV
                     YPDKCLLLVDTYDVLNSGVPNAIKVFKNISEKGYKPMGIRLDSGDLAYLSKEAKKQLD
                     NAGFSDISITASNDLDEYTITSLKAEGATINSWGVGTKLITSFDSPSLGGVYKLAASC
                     EKGVLEPKIKISENPEKINNPGYKKVIRIYNEDNKAEADLIMLHDEVIDESKPLEIFH
                     PTYTWKTKVFTNYKVKELLKPLYIKGRCKYNKKAVLEIKNHVQYELSTIWEQYKRLSK
                     PHIYKVDLSRNLWYLKTQMIDSKKVL"
     gene            9278..9862
                     /locus_tag="PC494_000497"
     CDS             9278..9862
                     /locus_tag="PC494_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore maturation protein A"
                     /protein_id="HDF3911025.1"
                     /translation="MIIIGKIWFYMVSIGIIGSLISKNMGELNKVILSETSKGIEFAI
                     SLAGIMALWMGIMNIAKESGLIEKIGQKLNPIMRRLFPSIPKGHKAMSYIVMNIALNM
                     LGAGNGATAFGLKAMSELQTLNNKKDTATNDMIMFMVINISSIQIIPFTIIKLRMDMG
                     AQNPSEIIFTTLFATIISTAVAIITCKFFQRRYR"
     gene            9878..10399
                     /locus_tag="PC494_000498"
     CDS             9878..10399
                     /locus_tag="PC494_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore maturation protein"
                     /protein_id="HDF3911026.1"
                     /translation="MEIFSNLLIPIIILYIVVYGKYKKIDVYDSFVKGAIDGLKAAWD
                     ILPYIIGIFLAIGIFKTGKGLDMLEWLFTPIANMMSIPKELIGLISVKPLSGSGALGM
                     YSELANRVGIGSLVEKMGATIVGSSETIFYTMAIYYGSLKIKNTRHTLSCAMISHVAG
                     VIAAVFICYVIFV"
     misc_binding    10465..10711
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            10795..12732
                     /gene="metG"
                     /locus_tag="PC494_000499"
     CDS             10795..12732
                     /gene="metG"
                     /locus_tag="PC494_000499"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HDF3911027.1"
                     /translation="MSKPSFYVTTPIYYPSGGLHIGHTYSTVAADTIARFKRFCGYDV
                     KFLTGTDEHGEKIQKKAIEQGMSEIEYLDGMIKDIKALWNTMDISYDDFIRTTEKRHT
                     DIIQKIFTKLYEQGDIYKGEYEGRYCTPCESFWTESQLLEGNKCPDCGRETYLVKEES
                     YFFRLSKYEDRLKELFKDDSFCFPAARKNEMVANFLDKGLEDLSVTRTTFDWGIKVPF
                     DEKHVIYVWVDALCNYITALGYMTDNDEEFKKYWPANVQIVGKEIVRFHTIIWPALLM
                     ALGLEVPKQVFGHGWILFADDKMSKSKGNVVYPEPIIERYGIDTLKYFLLREFAFGQD
                     GSYTHRNFVTRINYDLANDLGNLISRTVAMVEKYNNGIIPTAKVSTNFDADLKEQAVS
                     TRENFEAEMDKMQFHEALESVWKLVRRTNKYIDETMPWALAKDETKKDELDTVLYNLC
                     ESIRIIATLINPIMNETANKIYEHIGIKGQDDITTWESTKTFGLIGENVKVFKGEPLF
                     PRLDVEKEIEELTKMFSGKPPVEEKPLEHKEEITIDDLDKIELRVGKIISCEKHPKAN
                     KLLVSQVKIGPETRQIVSGIAEYYKPEDLVGKEVTVVCNLKPVKLRGVESQGMILAAG
                     DDGDPYVLPFTQGAKDGCEVR"
     gene            12762..13532
                     /locus_tag="PC494_000500"
     CDS             12762..13532
                     /locus_tag="PC494_000500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HDF3911028.1"
                     /translation="MLFDSHAHLNDESFDEDRDELIGSLKDKGVDLVVNPGADIETSI
                     TAIELAKKYDFIYSAVGVHPHDVSKLDDTAIETLRKLATENEKVVAIGEIGLDYYYDY
                     SPREEQKEWFKKQIELANELKLPIIIHDRDAHGDTFEIIKNTKNPEIGCVLHCYSGNV
                     ELAREYVKMGCYISIPGTVTFKNNKKTREVVREIPLERLFIETDSPYMSPEPHRGKRN
                     NPSQVSFVADKIAQEKGISYEEVCRVTKENAKKFFNIK"
     gene            13869..14300
                     /gene="phnG"
                     /locus_tag="PC494_000501"
     CDS             13869..14300
                     /gene="phnG"
                     /locus_tag="PC494_000501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate C-P lyase system protein PhnG"
                     /protein_id="HDF3911029.1"
                     /translation="MYTVDSTKILINMNLEKLEKIYSMIKDTSSISIIKEPNLATVMV
                     RANESVKNTTFNLGEILVTECSVKVDESLGYGIVSENNNKKAIYLAVIDAVLHSNNSK
                     FDELKNYINKSVYEENLRYEQEIIDEFSLINKTKVQFNAMD"
     gene            14315..14890
                     /gene="phnH"
                     /locus_tag="PC494_000502"
     CDS             14315..14890
                     /gene="phnH"
                     /locus_tag="PC494_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate C-P lyase system protein PhnH"
                     /protein_id="HDF3911030.1"
                     /translation="MVNYTQEIYRKMLDSASFPGKLNNIDNINIENNTKLLNGAIGIA
                     ITLLDQEVTFYIENYTQKDIKNIRALTMSNQIDYRKSDYIFLDINSEVDILQIKIGSF
                     EYPDESATIVHQVNDLSTYSQTKYIKLDLSGPGIKSKNSIYINGIREEFIERLSSINK
                     DYPIGIDLILVDKKGEIAFIPRSSKLSWEVL"
     gene            14893..15978
                     /locus_tag="PC494_000503"
     CDS             14893..15978
                     /locus_tag="PC494_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon-phosphorus lyase complex subunit PhnI"
                     /protein_id="HDF3911031.1"
                     /translation="MAYVAVKGGEEAILQAKNILEFYRVKGDSLPIDVKQIEEQMSYA
                     VDKVMSEGSLYNKELSALAIKQAQGDILEASFYVRALRSTMPRITYSEPINTEEMRIK
                     RRISATFKDIPGGQYLGATRDYENRILNVELLEEDEKKNRHFRDSFINELETVDEIPE
                     FTKISNIFRKENLLQEEVCENKLEEVIDDITRNSLRFPVSRSAKLQALTRGESGVVSG
                     FAYAIVRGFGDEHPYISELRTGNVFIKVKHPIYEDEEIIIGDMLVTECEIVSKASQNK
                     TENSKTNSEDKNKMSLGYGLCMGNNENKAISMAILDKSLEPNSEKLAQDEEFVLLHID
                     GIDSLGFISHFKLPHYVDFKADVERIK"
     gene            15998..16867
                     /locus_tag="PC494_000504"
     CDS             15998..16867
                     /locus_tag="PC494_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-D-ribose 1-methylphosphonate 5-phosphate
                     C-P-lyase PhnJ"
                     /protein_id="HDF3911032.1"
                     /translation="MIYNYGFLDENTKKEIRRKILKAISIPGYQVPFGSRELPIAKGW
                     GTGGLQLTLSLIGKNDVVKVIDQGSDDSTNACNIRSFIASVSNVETTKDTLEATLIQT
                     RHRIPEEKLKSNQILIFQVPIPETLRIVEPSEVETRRMHSEEDYSRMWVYLYEDIVRF
                     NDISIAVEYPCKVNDRYLMNPSPIPRFDIKKLNMSDNLFLFGAGREKRIYAIPPYTKV
                     EPLEFEDYKFEEEKFEGKYCSLCNSTNTFLDEVYDSDTNEKYYSCSDTSYCEKVRLKN
                     NSIDVTIGGTWNE"
     gene            16860..17726
                     /locus_tag="PC494_000505"
     CDS             16860..17726
                     /locus_tag="PC494_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDF3911033.1"
                     /translation="MSKINDSKRLENIDKQVLIGRNINLIYGDGCEKCFESTGYESNN
                     ICKYCGSIVACNNVNLELYEGEVLGIVGESGSGKSTLLKILFFQEHANSGEVYISHYN
                     KDTNILELSDQKKRYIKNHFMGIVYQNPHLGLNLDFSSGGNIAEKLLMANLYNVEKIR
                     DRGKELLIKTNIPVERIDHKPKYFSGGMQQRVQIAKALSNNPPILLLDEVTTGLDVSV
                     QAEVLDLIREIQRELKISMIVVSHDFDVIKMLADRTIVMKNGSVIESGLTDQIMEDPQ
                     HPYTQQLINSLL"
     gene            17767..18476
                     /locus_tag="PC494_000506"
                     /pseudo
     CDS             17767..18476
                     /locus_tag="PC494_000506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892101.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
     gene            18477..19646
                     /locus_tag="PC494_000507"
     CDS             18477..19646
                     /locus_tag="PC494_000507"
                     /EC_number="3.6.1.63"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-D-ribose 1-methylphosphonate
                     5-triphosphate diphosphatase"
                     /protein_id="HDF3911034.1"
                     /translation="MIKLIHNANIVLEDMILENGHLIIEGDTIKKVSNDKIDYAFDFN
                     EIDEIIDAKNLYVIPGIIDIHSDAIEKEIEPRPSTLLPFNMAFYELDKKLPANGITTV
                     YHSISLGDGVGVRSIDNSLKMIKNIDSYKNIDSKSINHKVHLRYEVLYYEGLEKVLEL
                     LDENKIDYLSIMDHSPGQGQYTNPTFYKEYATKVWGVTENYVDTWLDDLVNLHDNLDW
                     NKIANIIGIAKTKNINVASHDDDTLEKMDFIKNIGINVSEFPITLEVAKHSKKLGVLT
                     CLGAPNIVRGKSHNNNLKAMDAILEDCCDIVCSDYLPSAMIKSMCIVAERINNLNKAV
                     SLFTSNPAKAVGIYDERGSIKENKKADLVLVDIDSEYPKVVNTIVNGKTVYKREV"
     gene            19650..20486
                     /locus_tag="PC494_000508"
     CDS             19650..20486
                     /locus_tag="PC494_000508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PHP domain-containing protein"
                     /protein_id="HDF3911035.1"
                     /translation="MLTELHCHTSISDNNFTTEEIIKKAAEKNINILAITNHDTLSGL
                     DEALVLGEHYGITIIPGIEISAYDYKNRKRVHILGYNIDLNSQEIKNLCNPMVCDRHK
                     ASVKMVNKIIDLGYKISLEDVKKYSSKTGIFKQHIMKALIDKGYTDNIYSNLYKELFH
                     RGNGKVYVSLKYVDYRDAIKAIKNSGGICVLAHPGQMDNFSAIEEMVKVGLDGIEVYH
                     PSHNKELEKESLSYAKKYNLVVTGGSDYHGFYSQHNYELGSKSLNKEDLFKFRLALGG
                     VL"
     gene            20487..21482
                     /locus_tag="PC494_000509"
     CDS             20487..21482
                     /locus_tag="PC494_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDF3911036.1"
                     /translation="MSFLQVKNVGKSYGQVKVLKDISIDIEKGEFICLLGPSGCGKST
                     LLRIIAGLEDKHGGKIIINDKDMTNSPPESRNFGIVFQSYALFPNMNVYKNIAFGLEN
                     KNISKSNIDKKVKEVLEVVELSGYEKKYPSQLSGGQQQRVALARAIALEPDFLLLDEP
                     LSALDAKVRLKLREQIRSLHRKLGITTIMVTHDQEEALCLADKMVVMNRGEIIQVGTP
                     KEVYKNPETPFVADFIGTINFIDDGINKIAIRPEDIKVESNRDSKDKDIKVGEILDIE
                     FRGFNYRITVEYRSKQMKLDVVSKVAEQMKLCIGSKINFKIPKEGIVQYKSEGCA"
     gene            21500..23188
                     /locus_tag="PC494_000510"
     CDS             21500..23188
                     /locus_tag="PC494_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative 2-aminoethylphosphonate ABC transporter
                     permease subunit"
                     /protein_id="HDF3911037.1"
                     /translation="MITSKNKRRISDSTIQKYFLIFSVIVLIVFILFPLVSLLKNAFM
                     DTSGNFIGISNFSKYVENPSLIASFKNSIFVSTVSSLISLCLAFIYSYAITRTNIKFK
                     EFFKTMGMFPLFAPTMLYGISLIYLFGNKGIFTTMGLEVPLYGPLGIIISQILFTFPQ
                     AFLILSVALSMADYRLYEAADSLGASEFKKFCKITIPGIKYSLLSSFFVSFILAFTDF
                     GAAKVVGGNYNVLATDIYKQVVGQFNIPMGATVSMVMLIPVLIAFTLDKMASKKQGMT
                     ITAKSMPYKIKENKFRDRVFLIVCSFITLLIFILIFVSVIGSVIKLWPYNLSFTMEHY
                     TFKGILGSGIKTYLSSLKISTLTAIFGTIFVFFSAYMIEKVDKFPKLRQTAYLLSMIP
                     MALPGLVLGISYITFFNSASNPLNFLYGSTAILVIVNVVHFYSVCFITSNSSLKMLDK
                     EYELVAKSINIPFYKVFFNITVPMSITSILEIVVYYFVNSMVTVSALIFLYTPQTQTA
                     SISILKLDEIGYIGPSAAMAVLVLLTNIIVRLLYEFVTKKLKNNTQKWQQKDVA"
     gene            23200..24267
                     /locus_tag="PC494_000511"
     CDS             23200..24267
                     /locus_tag="PC494_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative 2-aminoethylphosphonate ABC transporter
                     substrate-binding protein"
                     /protein_id="HDF3911038.1"
                     /translation="MKFKKLVSLGVLSTLLLSVITGCSTDSSGSDSKSDSKTKGDLTV
                     YTAIEEDSIEPYLATFKEKYPDIKLNIVRASTGDITARLLAEKDNPQADVVWGVAATS
                     LLVADDQGMLEPYAPKGSEEIESAFKDDKEVPSWVGIDAWMTGITVNTKELSDKNIPV
                     PSSYEDLIKPEYKGLISMPNPSSSGTGYLTVSALIQIMGEEKAWQYMDKLHENIGVYT
                     QSGSAPATSAASGEYPIGISFGYRGIKLKEEGYPVEVVFPKEGSGWDIEANALVKKDN
                     IKEASKVFLDWAISKDAMNEYSKNYAVTTISTGNPIPEGFPKKPLEQMIDNDLKSAAK
                     NREDILNKWISKYDGKTEKES"
     gene            25031..26098
                     /locus_tag="PC494_000512"
     CDS             25031..26098
                     /locus_tag="PC494_000512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative 2-aminoethylphosphonate ABC transporter
                     substrate-binding protein"
                     /protein_id="HDF3911039.1"
                     /translation="MKFKKLVSLGILSTLLLSVITGCSNVSSGSNLKSNNKTKGELTV
                     YTAIEEDSIDTYLATFKEKYPDIKLNVLRLSVGGITARLLAEKDNPKADVLWGVAATS
                     LIILDDKEMLEPYAPKGFDKVNSAFKDDKKVPSWVGIDAWMTGITVNTKELKAKNISA
                     PSSYEDLIKPEYKDLISMPSPASSGTGYLTVSELIQIMGEEKAWQYMDKLHKNIGVYT
                     QSGSAPAILAASGEYPIGISFGNRGIKLKGEGYPVEVVFPKEGSGWEIESNALVKKDN
                     IKEASKVFLDWAISKDAMNEYSKNFAVTTIDTGNPVPEGFPKNPLEQMIDNDLKSAAR
                     NREAILNKWIEKYDGKTEKES"
     gene            26290..26820
                     /gene="rnmV"
                     /locus_tag="PC494_000513"
     CDS             26290..26820
                     /gene="rnmV"
                     /locus_tag="PC494_000513"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HDF3911040.1"
                     /translation="MIKEIIVVEGRDDVTAVKRAIDAELITTGGFGFPKGVMERIKAA
                     NERRGVIIFTDPDFAGEKIRKKIASEVPGCKHAFLPREEAKKDGDIGIENATPQSIIA
                     ALNKVRTENTEKRDEFKQVDLIRNGLIGNEEASLRRDALGKILGIGYGNAKQFLNRLN
                     NYGVEREEFIDALKQI"
     gene            26991..27860
                     /gene="rsmA"
                     /locus_tag="PC494_000514"
     CDS             26991..27860
                     /gene="rsmA"
                     /locus_tag="PC494_000514"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HDF3911041.1"
                     /translation="MDRLSSHNATKEVVQKYNFKFSKSLGQNFLIDSNIIDKILSGAR
                     ITRGDNIIEVGPGIGTLTREMGKIAEKVVAIEIDRNLIPILKDTLSDLDNTEVVNQDI
                     LKVDIQELVKDKLNGGPVKLVANLPYYITTPIVMKFLEEDIPVTDIVVMVQKEVADRM
                     NAIPGTKDYGALSIAVQYYCDTEIVAKAPRHMFIPQPNVDSTVIGLHVRDKRKYDVHN
                     EDIFFKTVKASFGQRRKTLLNSLGGLGFLNKDEIREVLKEANIDEKRRGETLSIEEFS
                     VLSNIINTKVSSK"
     gene            27926..29188
                     /locus_tag="PC494_000515"
     CDS             27926..29188
                     /locus_tag="PC494_000515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3911042.1"
                     /translation="MGSKRKFKRDYIILEAKDINFRYKERVLPKAFAKVEVNDEKAII
                     ALYVENLKYVKDGYKAVAIKDDHGLIDLGNIILNEQGRGEFVLDLEDYDDEIKGIALL
                     YERNIPLIGFKGNKLENYEDILFQEVEEEEYEEYEELEEEDEEIEENEESDRDEDSEE
                     EYIIEEYDEDEYEDYWEDDEDIEEGELKARTEVEDSDDEEIEEFNNYKEIENYNRVKV
                     QEEYIDIEYDEEEEEEEVFEVNREEDRFVSSKPTKSKKVQKDQNNIEKIKRANGVSQG
                     ESGNKQTSTLLMPRQIKKGLKLFKEVKPFVTDYIDKTRWWKIEINPTTLCGYTMPYLG
                     YLNVLNYTMYSDAVLHSYKYRHYLFGVQYDEYNKRKHYIYAIPGNRNEQPDNGSTGFL
                     RYQACDNRTNSLGYWLCFIDSRQRNIVR"
     gene            29339..30454
                     /locus_tag="PC494_000516"
     CDS             29339..30454
                     /locus_tag="PC494_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HDF3911043.1"
                     /translation="MINEQRILNEFLELVQIDSLSLKEGNVAKVLVKKLEEIGCSVVI
                     DNAGEKANGETGNIIATLKGNKEGKKILFSSHMDTVTPGIGVKPIVDEANGIIKSDGT
                     TILGSDDKAGIAAILEGLRYINENNIEHTDIQVVFSICEECGLVGAKNLDYGKIDSEY
                     AFILDSGGSPGEIIVKAPAQDVINVKILGKTAHAGLEPEAGISAIMVAARAIENMNLL
                     RIDEETTANIGIINGGTATNIVTGEVNIVAEARSLKENKLDVQTKHMVETFEKAAKDF
                     GAQIEIDVNRAYTPIDVSEDSEIIKLAKKAFSNLGIEGHTESTGGGSDTNILSKNGIE
                     AITLGIGMKNAHTLSEHIAIKDLYDSAKMVVEIIKEA"
     gene            30640..31536
                     /locus_tag="PC494_000517"
     CDS             30640..31536
                     /locus_tag="PC494_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HDF3911044.1"
                     /translation="METRYEEANKITIQSILWNIVLTIIKVIAGVIGNSSAMIADGLH
                     SASDIISSIGVLIGNYVSSRPGDREHNYGHEKAETLVSFVLSILLIFVSITIGIEAIK
                     SLFNLDALSVPSILPLVVSVISILIKEYQYRITIKVAKKINSPALKADAWHHRSDALS
                     SVAAFIGIGGSILGFKPLDPIASVVVAIFVAKVGISILISSVNELMDVSVDEEEIKEL
                     KFIVADTEGVKNLGDIKTRKHGAMAYVDLTICVDENLTVKQGHDIATKLEKHIIKHME
                     FVKGITVHVEPCTNCQGNKCNN"
     gene            31606..32403
                     /locus_tag="PC494_000518"
     CDS             31606..32403
                     /locus_tag="PC494_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3911045.1"
                     /translation="MSKKRKLKKKAAILIGVVVFFIIYFISFRIGINMEKDKSEVPKK
                     VEKEEEDNRSLRTQIKEKKKVYISDKNIENIKIEEDMWDEIKLFFSDFKKVRNTTSSY
                     EAVYEGYSDDGVKFSTDLNFFRVYTVNKEEYYKVPVSSKDAFKKLLDESIYTSFDLLS
                     HYKDWKEVTITHGKEIKKVHRWKFDDLAHKMISKRVVGKVQPEKSKERSDYNFTINIK
                     GDNFDVKVDTMGKDYVKVTSKKNVSYYEVHTSLFDYLKNEIFEIGKK"
     gene            complement(32458..33810)
                     /locus_tag="PC494_000519"
     CDS             complement(32458..33810)
                     /locus_tag="PC494_000519"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HDF3911046.1"
                     /translation="MNIHFIGIGGISMSALAEICINKGYQVSGSDSNESYLLDKLRDQ
                     GATIYIGQKKDNISDDVNMVVYTAAVHPDNEELVAAKEKNKLVMNRATFLGQIMREYK
                     NSIAVSGTHGKTSTTSMLSTIFEYADLDPTILVGGNLSMIGGNVKIGNSNHFITEACE
                     YVDSFLNFNPKISIVLNVEEDHLDYFSGIDEIKASFNKFGKLLPPEGYFIINGDDENI
                     DDILYDVKATIIKYGRDSDNDAVIKDIHFDNSGHGIFRIEYEGRDLGEFELSVYGLHN
                     IYNASSAIMAALVSGIDLETIRKNIKIYKGVGRRFETKGYYKNALVVDDYAHHPTELK
                     ATLAAAKKLKKSTLWCIFQPHTYTRTKSLLGEFSEAFYAADKVIITDIYAAREKDPGD
                     IHSKDLVEKLYQNNVDAIYIKEFEDIVKYLRENVKDNDLVITAGAGPIYKVADLLVEK
                     "
     gene            34029..34907
                     /gene="purR"
                     /locus_tag="PC494_000520"
     CDS             34029..34907
                     /gene="purR"
                     /locus_tag="PC494_000520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HDF3911047.1"
                     /translation="MKFKRTERIGAIVKILSDNPNKIYTLSYFTNQFNAAKSTISEDL
                     LVVKNVFEKLHLGKVITISGAAGGVKYIPKTSIAENAEFLMELCERICDKSRILSGGF
                     LYLIDLIYDPTIAAKIGKIFASNIEYVDADYVVTMETKGIPMALMTAKAMNLPLVIIR
                     KDIKVSEGPTLSMTYVSGNSSKVESMSLPRKALKPDSKVIIIDDFMRGGGTIKGMVDL
                     MNEFGAEVIGTGVFISTTNPSEKMVKDYISLIQLDVNGDKIVVEPNLKTFKDEYRNED
                     LDEEEDSEFEFEIDED"
     gene            35063..35341
                     /gene="spoVG"
                     /locus_tag="PC494_000521"
     CDS             35063..35341
                     /gene="spoVG"
                     /locus_tag="PC494_000521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation regulator SpoVG"
                     /protein_id="HDF3911048.1"
                     /translation="MKITDVRVRKLTEEGKMKCIVSITFDNLFVVHDIKVIEGHNGLF
                     IAMPSRKVGEGNFRDIAHPINAEMRQVLEDAVLQAYHEALVQWEVAAE"
     gene            35554..36933
                     /gene="glmU"
                     /locus_tag="PC494_000522"
     CDS             35554..36933
                     /gene="glmU"
                     /locus_tag="PC494_000522"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HDF3911049.1"
                     /translation="MNFKAIILAAGKGTRMKSKYPKVIHKVCGKEMVNHIIDVSKKSG
                     VKDTVVILGHEADVVKEKLAEEIIIAMQTEQLGTGHAVKMAKEYINDEDTIVVLCGDT
                     PLIKEETLKRLFEYHIENKYHATVLTTRVGNPTGYGRIIRDKKGDLLKIVEQKDANSE
                     EKMISEINSGIYCFNGKSLREALDLLNNNNSQGEYYLTDTAKIMRDKGLKVGAFAGST
                     IEELMGVNSRVELSKAEEIMRRRINESHMVNGVTIIDTNSTYIESDVMIGNDTIIYPG
                     VMLQGKTRIGSDCIIGMNSSITNSEIGDGTEIKNSTIIDSKVGENSTVGPYAYLRPKS
                     DLGNNVKIGDFVEVKNAIIEDGSKASHLSYIGDAHVGKNVNIGCGVVFVNYDGKNKFK
                     SIVKDNAFIGSNSNLVAPVVVEEKGYIATGSTITHDVPDGALAIARERQVIKEGWVEK
                     KNQKDDQSK"
     gene            37028..37978
                     /locus_tag="PC494_000523"
     CDS             37028..37978
                     /locus_tag="PC494_000523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003361732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate pyrophosphokinase"
                     /protein_id="HDF3911050.1"
                     /translation="MNTSGSEIKIIAGNSSKELAQKIADYIGVSVLDCEVGTFSDGEI
                     CVNMNETVRGCDVFVVQSTNSPVNDNLMELLILIDALKRASAGRITAVIPYYGYARQD
                     RKAKARDPITAKLVANLITAAGADRVLTMDLHAAQIQGYFDIPLDHLLGGTILANYFN
                     EKKIEDLVVVSPDLGSVTRSRKFANTLNGEVPIAIIDKRRPKANVCEVMNLIGDVKGK
                     NVILLDDMIDTAGTIVNAANALKEFGAKDVYACCTHGVLSGPAIERIANSEISELIVL
                     DTIQLPEEKRIDKIKIKTVAPLFGDAIRMIFSNESVSKLF"
     regulatory      38816..38901
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01786"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class II; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01786"
     gene            39063..39584
                     /locus_tag="PC494_000524"
     CDS             39063..39584
                     /locus_tag="PC494_000524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HDF3911051.1"
                     /translation="MKLKKNKKGFTLVELLVVIAIIGILAVVAVPALFSNINKAKVAS
                     VESDYSSVKSAALSYYSDTNKIPVTPDGQTGLSVLETYMESLPDKADIGGKYKLIKVG
                     NKLVLQIGTNTEGVTLTEAQSAKLLSDIGENKIYTSTTTNSLGNPLTSNTKIDNNVLY
                     IVLIDNTVMDTTK"
     gene            39735..41411
                     /locus_tag="PC494_000525"
     CDS             39735..41411
                     /locus_tag="PC494_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II/IV secretion system protein"
                     /protein_id="HDF3911052.1"
                     /translation="MAKKVRIGDKLVEKGYITEEQLKWALSEQKNSGKRLGEFLVQEG
                     LIDSNLLISVLKELLDIESIFLEGTEIDTLATKMVPENICKRYTVFPFKIDGNKICLA
                     MSDPQDREAVQDVRRMSGKDVEIFISSTEDINKAIGHAYAHSEINKAMTEYNKNRTGG
                     VRETVILEEDVNAAPIVRLVNNILENAVRMEASDIHIEQSENYMRVRFRIDGMLREYM
                     RMNSAPYKAVISRIKIMSDINISEKRIPQDGRIYLKVDNKPIDFRVSTMPTNRDEKIA
                     MRVLDKSNFMVSKEVLGIDEHGSKIYDELINTPYGLILVVGPTGSGKTTTLYSMLNQL
                     NTENRNLLTIEDPIEYELPGVNQSQINEKAGLTFASGLRAFMRQDPDIIMVGEIRDTE
                     TAEIAIRASLTGHLVLSTLHANTAVGAISRLLDMDVESFLITSSVLGVISQRLTRKIC
                     EHCKVSYEADIGEKKALGIDVNESVTIYRGKGCERCNNTGYKGRLGIFEMLEITPEIK
                     ELIDSSANQREILKMARKQGMVSLKEDIVKKVLNGKTTVEEMIRIILMTD"
     gene            41423..42631
                     /locus_tag="PC494_000526"
     CDS             41423..42631
                     /locus_tag="PC494_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system F family protein"
                     /protein_id="HDF3911053.1"
                     /translation="MKSFKYTVIKEDGKKQTDVIEANDFNEARNLLRKRNLRVIEIKE
                     SKNKNIRLSSIKRKKDLGADQISHFCRQFAIIVSSGINSISGLETLARRSTNITLREE
                     INRIVAEIKVGSTIADSMLSSKSKFPKLLGAMVATGEATGKLDEVLKSMASFYASEHR
                     VKQKLRNAATYPLIVLISSFIMIFIFTTFMVPKMINSITTVGATLPLITRIVMGFGMF
                     MKKFWIIVLLVIILFIYQFKKYLKTSVGRAHKDRVINKIPVLGKGINCMVATRFSRAL
                     YLFVSTGYPLVQGLDYIIDSVNNTMAEKILASAKDGITRGEGLAENLERYTYFDSVLV
                     QMIAIGEQTGELENISRQMAEFYEYESEIYLNRMASMIEPVLIIAVGIIVAILVVSIF
                     MPMLSIYDAM"
     gene            42646..44358
                     /locus_tag="PC494_000527"
     CDS             42646..44358
                     /locus_tag="PC494_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PilN domain-containing protein"
                     /protein_id="HDF3911054.1"
                     /translation="MNKVYVSYYGDSISIVEGRYKHDKDKFYVKNFNVFSIEDIAQDF
                     SKEKYALLRYALENVKLKSRHVVFCLNTRDVILKPQKLPNMDKKDLDGFMKLEMDEMM
                     ALESDEYVFSYEVSSETPDNSDGDESSLNLIIGAIQKEEVNAIVEIMHEFDLVLDRID
                     TLSTAYLRMLKNLDYNDIMVTNISDNSTIINIYKKDTLFISDNIPIKITAKDMDMQLL
                     NVVEESKGLMNYYSSRNFGKVTDTILILGKRYSNKLIYETFSSAFSSYVSQGLTEIMD
                     ISDMITGDIDEDDINSIVELLGSMIEPKGKRDFENINFLPMDILRKQIKAKQMKNILK
                     IAPIVILILAIPYLCLIFSNNLANKELENVNGEIRNIESAYYQIGNIEKMIQSKSEEI
                     KVYDMLIGKKVKWENLLDDIDKNTPSKVELTSLSTTYQNLGTNNKADNSKSNKTTTDK
                     SSNNETKSSTKSDSNGDKTDNDLNEDKTTNVSEALTGNSETNSNNTDKDDKTPLYDKI
                     PNVINIEGNAKDSSYVGQFLYKLKGLYYFKDVKLHSIKSNAEDSNYTFSMTLYLKEGV
                     LTNE"
     gene            44351..45259
                     /gene="pilO"
                     /locus_tag="PC494_000528"
     CDS             44351..45259
                     /gene="pilO"
                     /locus_tag="PC494_000528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 4a pilus biogenesis protein PilO"
                     /protein_id="HDF3911055.1"
                     /translation="MNKDIFKKDIKDIFKMEVSLKGILIKVIILLAILSYGYFGLYPQ
                     YQKYIATKNSVKQATEKLNIYKEKTALMPKYEKQLEEVESELKEKSKNLLYDMQDGLF
                     LIGLDKKMKAYNIDLTSYDVGNVKEYEHFYGISTTISVRGDYRNVKKLMAYLEEQKNV
                     TQILDYTMTSYIEPEKEEEETTNNKDLIKNVNINKDTKIYWVEGENKWHLYKDCPLIK
                     EGEIIKNDKLLDRSTNYLCNTCVLRAATEKEAKKEVVAPKAEGVVDATFKFIMYTKEN
                     TTMILDTDNPSSWRPGKYNPFKSSAK"
     gene            45286..45852
                     /locus_tag="PC494_000529"
     CDS             45286..45852
                     /locus_tag="PC494_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HDF3911056.1"
                     /translation="MSLYKNNEKGLTLLEVIIAVFILTIVLSISYKVFNGITSAVKKQ
                     QIITDAQVNINLINKYLNRDLENCKELTKTGSGNNYEYNIEMPDNVVKYEVSIETKKN
                     TEVYSVTRIQNNTIDTENEVREEIIYNQPLVQNNKEMKETPFKIEKQTGKSIYTVSIY
                     YNESVQESHKNSNLNNKTYTFDVMSRIG"
     gene            45889..46416
                     /locus_tag="PC494_000530"
     CDS             45889..46416
                     /locus_tag="PC494_000530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HDF3911057.1"
                     /translation="MSKKNSERGFSLIEVLVAMAIMGIVLFAFFNIINTNNKANTKND
                     TDITSLNYVQSEIENLREKIKSGEFDFDSLDKLEDGTVVYEKLIDKSKKVVYDKVLSE
                     GDVSLYDTPYEKITTIKDEDGNLIDKGNITNKIKTIVEDKSGQIYKIAVTGKSMNDYS
                     SKKEVKIVTEIFKDK"
     gene            46437..47975
                     /locus_tag="PC494_000531"
     CDS             46437..47975
                     /locus_tag="PC494_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3911058.1"
                     /translation="MRKWNKFKSERGAALVLVLVVVALLSIVGLIFSNQIANRIKSTK
                     TTNEGIQAKYLAETCVENSIDKAYEKLYDELEKMDNEFKSENQEKSISRSKLRNISDE
                     DFNNQDEENIEAERLGYMNNINFYLNKASSDLEKASMELKKLYDLDMLDYRDIEYVDA
                     NIISHRDSILEICKNYTSGDISKINEYILKEDIDSTTLIEAKLVNNDILLKKFLEENK
                     IENEHLNSAFSHTYKALDNISLAMQNMIEYRHTFHIDEPKVEVSNGIPDSQQYYELIQ
                     NPIINSMEYSWNSKWDTLENLLEILPNQTQGFNSLRVHLRNNVRKFEKLSDNISSGKK
                     NTAKNFLKYKELLYEISDQCNQLKSMSYEKIPVKYDNMALITTFDYIQNELLAEIKCR
                     LKELKPQEIDKTEGITIKIPFYKADYDMTKEGWPKLKENGSGAELSLMVTGDKNGIKE
                     VEVTDGKKNIIGLGVEENSNSKYKVDAIVNFNLNIDTNVVGNYDIKDKILINHDISSY
                     KKVN"
     gene            48071..49153
                     /locus_tag="PC494_000532"
     CDS             48071..49153
                     /locus_tag="PC494_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV pilus twitching motility protein PilT"
                     /protein_id="HDF3911059.1"
                     /translation="MYIYDLLEQGIRLNASDIHITVGTNPVARVKGGFVKLSEQILTS
                     EVTMQMAKDIAGESMFKVIEEHGEADFSASLKTGERFRVNAYRQKGNYAIAIRTITAE
                     IPTFEKLGLPESIKSFTEKHKGLVLVTGPTGSGKSTTLASMINIINEKQQKHIITLED
                     PIEYVHHHKQSLVNQREVGTDTESFHSALRAILRQDPDVILIGEMRDPETVSIALTAA
                     ETGHLVFSTLHTVGAAKTIDRIVDMFQPSQQQQIKTQLSTVCEGVVSQQLLPTADGKG
                     RIAAIELMFATPAIKNLIREGKTYQIPNMIQTGVKVGMKTMDQDLMELYKNGKITKDM
                     ALSRCTDQEFMTRMIGGVNYNGYYNR"
     gene            49134..49916
                     /locus_tag="PC494_000533"
     CDS             49134..49916
                     /locus_tag="PC494_000533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HDF3911060.1"
                     /translation="MDIIIVNLYVFIVGIVFGSFFNVCIFRIPEGISISRPPSHCMSC
                     NTRLKPIDLIPVLSYLMSGRKCRYCYEKISSRYAIVELITGLLFLTVFMLYGISTSTI
                     YYLVLVSLLIIITFIDIDHFIIPDKILVFGAIFSMIFNLLFKEIPVKDSILGVFICGG
                     SVWIIVLLIEFVIKKECMGGGDIKLFAMLGLYMGVKNGLLTALLSVYVGAVYGICVII
                     ISRIKGKEYNSVIPYGPFISIGALITILCGKKLLELYFSMVI"
     gene            50018..50668
                     /locus_tag="PC494_000534"
     CDS             50018..50668
                     /locus_tag="PC494_000534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HDF3911061.1"
                     /translation="MEYIIIISLFFAHLINKSLCVFCDREKKNLYNTFFIYIITVVLS
                     VLIYLKFGISVECVQYMVLIPFLIIISIVDYYTIYVYDITIVSGIIVQGIIFLAFFNI
                     AQFDYINHIFGLLIGFIIPYIIAKLTKGLGYGDVGLYSLCCFALGNNYGFYVIVLSFI
                     LAFLFFIILYITKVFKDVDIRKQIPFTPFISLSTILIIFTEYNIFNFYYNLLYKFI"
     gene            50682..51242
                     /locus_tag="PC494_000535"
     CDS             50682..51242
                     /locus_tag="PC494_000535"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HDF3911062.1"
                     /translation="MYVVVGLGNPGKKYEKTRHNVGFDVIDILAKEYNISVTKIKHKA
                     LIGEGRVGTEKVLLVKPQTYMNLSGETLIDIYKYYKVDLSNIVVVYDDIDLEVGKIRI
                     RKKGSGGTHNGMKSITNCLGSNDFPRVRVGVSKPEAGQDLADFVLSRFRKEESDNINE
                     ALEKAADAIDSIIRENIDMSMNKYNG"
     gene            51259..54645
                     /gene="mfd"
                     /locus_tag="PC494_000536"
     CDS             51259..54645
                     /gene="mfd"
                     /locus_tag="PC494_000536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HDF3911063.1"
                     /translation="MNDVFLYPLQNSKEYKDIINCIKNTKGSLLVNGLLPVQKPHISY
                     SIFNDLSRQMIFITSSDLEAKKVYEDLSFYMEDKVEYLGFQDIYFYHLDAKDRNEEAK
                     KLKVLLKLANKEKIILVTSIEAVLRKYIPKQVLLDSVSHYKVGDSLDLEKLTEKLVSL
                     GYERVSKIEGFGQFSIRGGIIDVFSLEYTNPIRMELFDDEIDSIRTFDVYSQKSIDKL
                     QQFSITPSREFIYPEKTTDALVKLKKETTKNTDEGTFQNIDYISSKTYFEGVENYIDY
                     IYPEENKSIFTYLADDAIVFINDITRLKERCENYINEFRENYKLNLERGLAIKNQGKL
                     LYHYTDLEYLVKDKSVVLNSLLPKSINNFSIKSIINFESREVPTFNGKVDLLVEELNR
                     LKYNGYKIILATNTLERANKLGKDLLDKGLETTISKDRDIEIKSSQVIIVPAHINSGF
                     QYKSIKFVVITDNEMIGVYKRASKTSNKKVKKGKKIESFLDLSVGDYVVHENSGVGRY
                     TGIEQITVNAIKKDYMKIVYQGGDNLYVPIDQMDKVQKYIGAEVEKVKLNKLGTNEWT
                     KAKAKVKKEIEDMTKDLIELYAKREKIQGYKFSKDTPWQAEFESLFPYQETEDQLKAI
                     EETKKDMESSKVMDRLVCGDVGYGKTEVAIRSIFKACMDQKQVAVLVPTTILAQQHYN
                     TFKERFENYPLRVEVLSRFKTPKQQKQIIEDAKKGLVDILIGTHRIISKDINLPNLGL
                     VVIDEEQRFGVKHKEALKKIKSTVDVLTLSATPIPRTLHMSLSGIRDMSVIEEPPQER
                     HPVITYVTESKESVIQDEIERELSRGGQVFFVYNRVEHIEEMASMIQKLVPDARVAVA
                     HGRMTSKSLENIILGFLNKDYDVLVCTTIIETGMDISNANTMIIYDADKMGLAQLYQL
                     RGRVGRSSRQGYAYLLYEKDKTLSEIAEKRLKAIREFTEFGSGFKIAMRDLEIRGAGN
                     ILGSQQHGHMAVIGYDLYVKMLNDAIKKVKGEPIVEEIDVEIDLSVNAYIPDNYIKDE
                     LIKIEMYKKIASIENKEDMLDIQEELEDRFSDIPKPVQTLLTIAYIKSLCKILKIEKI
                     RQLKDEILLVPITKYRTKQKIGYNIVTELEELLEKMCKVK"
     gene            54676..55671
                     /locus_tag="PC494_000537"
     CDS             54676..55671
                     /locus_tag="PC494_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HDF3911064.1"
                     /translation="MKKVITLVIAMILVVSVTACSSSKGETVATVEGTKISSDEFKKT
                     IALYKDSMEQTYGKDIWDKEVEKGVKYKDKFKDLILDQLITTEVIYSQAKKDNLLPKK
                     EDVEKSFKELKDAMGKDEKYKEQLKKLGIDDEFLRDQQEKDLAMQNYQSNFAKKTKIS
                     DEEMKKYYDTHKDEFKKDEVEASHILLKTVDDNNKPLSDKEKAEAKKKAEEALKEVKS
                     GEDFAKVAKKYSQDTSASDGGKLGFFSRGQMVAEFEDAAFSMKKGEVSDLVETQYGYH
                     IIKVTDRINEQTSFEDAKETIKDQLLKNKYQEQIEKLTKEAKVEKDEKVINKITI"
     gene            55795..56334
                     /gene="spoVT"
                     /locus_tag="PC494_000538"
     CDS             55795..56334
                     /gene="spoVT"
                     /locus_tag="PC494_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein T"
                     /protein_id="HDF3911065.1"
                     /translation="MKATGIVRRIDDLGRVVIPKEIRKTLRIREGDPLEIFTAKDGEV
                     ILKKYSPIGELNEFSQEYAETLAEVLGYGVLITDLDSIIAVSKLPKKDYKEKSISDEL
                     EAIISERTVKYSKDKNILPLFKEDQKEYTSQVIMPIISASGDCIGSIVVVSKDKDTIA
                     ESEEKSLKIAANFLGKQVQ"
     gene            56454..58067
                     /locus_tag="PC494_000539"
     CDS             56454..58067
                     /locus_tag="PC494_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HDF3911066.1"
                     /translation="MNNNKNKDSFLKGALILGLAGVIVKIMGGFFRIPLGNMIGSEGM
                     GYYQAAYPVYTLFLTLATAGFPTAVAKLVSEKVAIGNFKGANKIFKVSHTVLFITGII
                     SFCILFFGADYIVTNVMKNPGALYSMKAIAPALLFVPAMSAYRGYFQGRQDMTKIAVS
                     QVAEQFFRVVLGLTLAYLLMKSLGQTFGAAGAISGATIGSIASMLYLVFAYMLGRKER
                     RAEIDASQRFKDERVSYIFKKLLTVAIPITIGASVMPLVNMIDNVIVIRRLMEAGFTY
                     KVANSMFGQLTGMAMATINLPAVITTAMSMSLVPAISKAYALGNKSKARKDTKSAVKV
                     TLLIVLPCAFGMASLAIPIMGLLFPHEPSSVGTILFTLTPCVLFLGLIQTLTGIIQGM
                     GKPIVPVIALCVGMLCKIVISYTLTGIPDINVLGSAFGTVTAYFVAAMINLLYVKKHM
                     NVNFSKKEFIIKPFITVMTMFIMVKLSYGALVGFLGNSISTIIAICVGGIVYVVVILG
                     IGGIKKEEILTMPKGDKLYKLLKKVKLIR"
     gene            58174..59622
                     /gene="mazG"
                     /locus_tag="PC494_000540"
     CDS             58174..59622
                     /gene="mazG"
                     /locus_tag="PC494_000540"
                     /EC_number="3.6.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside triphosphate pyrophosphohydrolase"
                     /protein_id="HDF3911067.1"
                     /translation="MGKISIVGLGPGDYSLISQGVLESLINSPKVFFRTEKHPIIDKL
                     KETIQYTSLDYFYEKEENFDNVYLKISEFIIEESAKGDLVYAVPGHPRVAEKTVSIIE
                     RLANEKHIAVEILPSMSFVDAMFNYLAIDPSEGFKLVDAFEIENSYIDLDTSMIITQV
                     YDKFIASNVKLKLMEHYDYNQEVCIVNGAGVKDLESKKFIKLCELDRNENFFDYLTSL
                     YIPKSSKKMYNTVHDLEIIVNTLRSPSGCEWDKKQTHQSLKNSVIEEAYELCNAIDNN
                     DIDEMVEELGDVLLQVIFHCQIGNEEGYFDLKEVVNGICKKLIHRHPHIFSGAKLDMS
                     KFEKTWEELKKEEKGESTITDGLRRIPKHLPALMKASKVQHKAALVGFDWDNVEDVFK
                     KIEEEYQELLDEHRVGNIKYIKEELGDLLFSIVNLARFLDIDSGEALNCTTEKFINRF
                     DFIEKSAMNLNKKLEDMTLEEMDEFWNQAKKQ"
     gene            59711..59989
                     /locus_tag="PC494_000541"
     CDS             59711..59989
                     /locus_tag="PC494_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003153447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HDF3911068.1"
                     /translation="MNKAELVSKMAEKSGLTKKEAEAALNAFMSSVQDALVNNEKVQL
                     VGFGTFETRERAARQGRNPRDPEQVIDIPASKAPVFKAGKGLKDIING"
     gene            60061..60303
                     /locus_tag="PC494_000542"
     CDS             60061..60303
                     /locus_tag="PC494_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HDF3911069.1"
                     /translation="MRLDKFLKVSRIIKRRTVAKDACDKGIVTINGKVAKSSSEVNIG
                     DTLEIQFGEKKMKFKINEVKEHVLKNDAKEMYEILE"
     gene            60365..60619
                     /locus_tag="PC494_000543"
     CDS             60365..60619
                     /locus_tag="PC494_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation protein YabP"
                     /protein_id="HDF3911070.1"
                     /translation="MEQNITLKDRSKLVISGVEHIYSFNDKRVELKTSVGEMVIEGEN
                     LDMSKLSIDENIISIDGTINSMVYAKPKKPQESFLKKVFR"
     gene            60620..61153
                     /locus_tag="PC494_000544"
     CDS             60620..61153
                     /locus_tag="PC494_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3911071.1"
                     /translation="MIPFTQDVSIFYATIYGGILIGVLFDFYRGLRGNFKFINYFAII
                     FDVLFWFLATVIIFVTINLTEFFDLRYYHFVALFIGFILYYNTISKIVLSIINKIIRF
                     VRNSFKKVTHYIVSFLNNLYYVIIYSLHLLFDIIFYIPNIFIATRKSIKRKSNKKLKN
                     KKKSKPKKKKNKTKKRV"
     gene            61159..61443
                     /locus_tag="PC494_000545"
     CDS             61159..61443
                     /locus_tag="PC494_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HDF3911072.1"
                     /translation="MNLRKKFSGQIIVISLFLGISIFSMMTGFVFEYTKAKEYKKEIA
                     SLNKQLKKTEIQINSLKKDEKSYEGDLEDIARKRLNMVKPNETVYVDINR"
     gene            61556..62476
                     /locus_tag="PC494_000546"
     CDS             61556..62476
                     /locus_tag="PC494_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ppx/GppA family phosphatase"
                     /protein_id="HDF3911073.1"
                     /translation="MKVGAIDIGTNSMRLLIADYRDGNFINRKKFVNTTRIGYGVDSK
                     GYIKEDAIKRNIKALKEFSDKCNDEKCEKIYCMGTSALRDSKNGDYFVKLAKEETGID
                     VDIVTGIEESNLGFKGVLEGIQGDDTIIVIDIGGGSTEFIVGDSEGIKFNKSENVGAL
                     RMTERFLKHDLIEDEEFEAMSSFIYGEIDKTLNHIKDRGLKTLIGIGGTITSLSAMNQ
                     ELEIYSMEKIHNSKIHKKEIEEILQKLIKMTLSDKKNLKGLQEKRADIITAGVKILNI
                     IMEKLEIEEITVSEYDNLEGLICQKSKKMY"
     gene            62566..64938
                     /gene="spoIIE"
                     /locus_tag="PC494_000547"
     CDS             62566..64938
                     /gene="spoIIE"
                     /locus_tag="PC494_000547"
                     /EC_number="3.1.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage II sporulation protein E"
                     /protein_id="HDF3911074.1"
                     /translation="MQRSVAVVKNKTVKPNVIKLISGYIDFTTAAFAVMGFLLSRSII
                     VDSVAPLGIAFFICASKIDKYKIPVFISTLLGILLSSNDFGNVAKYAVCLTIFMAMNK
                     KLKLSDSIAKVAFIGAIILLPISMGQAFFSNRYVYGLLIAGVESIIMFISIYVFSYGI
                     GLMANVNNRMSVRTEEAISISLLLTFSIMGIGDISLFGISIRTILSTVLILLTSIVGG
                     ATMGASSGVIIGVASILNNMTSAVYMGIYSFSGLISGAFNKINKYFCILGYILSWTII
                     YLYTSGITSNMMQLRDILLGCLIVLVLPERLFNKIEKLIKSNVASNEIVYDYIMRSKN
                     LTNSRLNSIYKTYDDLADTFDKIREKDKVLDQRDIANVIDMIHNDECKSCSMRRMCWE
                     SRFNHTYTMIYNILEKIEEKGELSLNDIPKNFRKECMKPESIVKISNHYYKMFVLDYD
                     WSVKFSESRKLIANQIRSISKSIKSLSQDLEGDIMLDIEKEKNIYEQLERYDITVDKV
                     SYLTKSNSEFEISIEKKTCHDGCMCEDKIVNIISDLVGENMSVRKIGCHCLGGKCKAT
                     FVKSQKYKAVTEVSAMSRDGHILCGDNYTYMEINDGKYMMAISDGMGKGKKAYEESSA
                     TIDILEKMIDAKIKDEIVIDTINNMLLLKSSEEMFSTLDLGILDLKRGCLETIKMGAC
                     STYIKREDGEVDLISSSSLPVGILSDVKIDRKNVKVKEGDYVIMVSDGIVDAGRNNNL
                     GDNWLIYFLKNIETTNPKEISNLILDRALELQALQIEDDMTVLVTKICTK"
     gene            65289..67181
                     /gene="pepF"
                     /locus_tag="PC494_000548"
     CDS             65289..67181
                     /gene="pepF"
                     /locus_tag="PC494_000548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HDF3911075.1"
                     /translation="MNRKLCKAIIPLFISIFCMLIISIKADQGYQKNNDRAITVMNNN
                     DTEDDAEKKQEIDYEKTCWNLQSLFKSDDQWKKELKSFDKDTKELKNYIGKVTKSPTH
                     LSFALNIKEKLDIRLNKLSAYVKLKQDTNKNSYKYLDMNDSMSKSYGNYMGICSDLEL
                     EILKLSNKDYKKIISNKNINRKYGAYLRDIRRNKVHYLDDKSEDILSKVSSISSLPSQ
                     VYELFRNMDRKTNLTPAQYASELESSDRENRKKAYQDELITYNDNINTIAGLITGQVK
                     KNIFYSQERGYESSLEMYLESDNVDEKVYNNLIRTVNSNMDSLHKYIDLRKKVLKLDK
                     VHSYDMFVPMVKAVDNNINYEKAQSIVYSALSPLGKEYNDVVYKAFNEKWIDVYSHEN
                     KVSGGYCLSVYENHPYILLNYNNSLGSVSTLSHELGHAVYEYLSSKNQNYFNSNPSIF
                     THEVASTTNEALLYEMLIKEAKGNDEKAYYITQYLDLIKDTLYTQTMYAEFEKTIHEL
                     VEKGKSVNALVLNDVWGQLLKKYYGQSYELDQLSKVGWARIPHFYNSFYVYKYATGCS
                     AGVSFAQDILKNGSDNYMSFLKKGSSDYPINLLKSSGINLTNTKPIENTIKKFDSLVA
                     ELEKLL"
     gene            67295..68260
                     /gene="galU"
                     /locus_tag="PC494_000549"
     CDS             67295..68260
                     /gene="galU"
                     /locus_tag="PC494_000549"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HDF3911076.1"
                     /translation="MQVKVKKAVIPAAGLGTRFLPATKAQPKEMLPIVDKPTLQYIIE
                     EAVASGIEEILIITGRNKKSIEDHFDKSVELELDLEKKGKKELLEVVQNISNMINIHY
                     IRQKEPKGLGDAIYCARHFIGDEPFAVMLGDDIVDNDVPCLKQLTDAYEEYRTTILGV
                     QKVNQEDTNKYGIIEAKNIEGRVYKVKDMVEKPESGKAPSNIAILGRYIITPEIFDIL
                     KDLPPGKGGEVQLTDALKILSKKEAMYAYNFEGKRYDVGDKLGFLEATVDFALKKEDL
                     KEDFIKYLKHVCSEFDKNNNVLYNNTDEKIDLIEVNEARELEIQK"
     gene            68760..70364
                     /gene="rho"
                     /locus_tag="PC494_000550"
     CDS             68760..70364
                     /gene="rho"
                     /locus_tag="PC494_000550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor Rho"
                     /protein_id="HDF3911077.1"
                     /translation="MRRIFLILDDKVLEGLGSKTLVELREIAKELKIKSITTYKKNEL
                     IEIINSKSKNEEKVNEETKEKNEDIKEDIKNRKENIERESIEKEVEYKSPTKSYNKKE
                     IDTQNISQNQEHRNQRNDYNKTTSVNDSNKSSNISNRMVRNNNKNYYMPKQVDESKIV
                     DEFNTSKEDEVVGVLEILPDGFGFLRGSNYLSTEGDVYVSPSQIRRFNMKTGDKIKGI
                     TRHPKSGEKFRALLYVQKINDENPDTAIQRNAFETLTPIFPEERLTLETNRNEIATRI
                     IDLISPIGKGQRGLIVAPPKAGKTVLLKSVANSIAKNHPNVELIVLLIDERPEEVTDM
                     KESIEGDVIYSTFDQVSSHHVKVAEMVLNRAQRLVEHGKDVVILLDSITRLARAYNLT
                     ISPTGRTLSGGIDPGALHGPKKFFGAARNIRQGGSLTILGTALVETGSRMDDVIFEEF
                     KGTGNMELHLDRKLAEKRIFPAIDIYKSGTRRDDLLLDDEEKTALWRLRREMSNNSVM
                     EITDKVIELIKRTKDNKEFVKSIKNL"
     gene            70517..70717
                     /gene="rpmE"
                     /locus_tag="PC494_000551"
     CDS             70517..70717
                     /gene="rpmE"
                     /locus_tag="PC494_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018591942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L31"
                     /protein_id="HDF3911078.1"
                     /translation="MQKEIQPKYNPVEVRCACGNTFVAGSTKDEIKVEICSECHPFYT
                     GKQKNIEKGGRIDKFKKRFKMD"
     gene            70862..71755
                     /locus_tag="PC494_000552"
     CDS             70862..71755
                     /locus_tag="PC494_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1385 domain-containing protein"
                     /protein_id="HDF3911079.1"
                     /translation="MAKQAVGGQAVIEGVMMQSKDKRAVAVRKSDGEIALKEDRIKSW
                     VRDKNIDKIPFVRGSFVMIDTMIQGIKSLNFSSEFFMEEAEEDKFDLFIKKIFKDKAN
                     DIIIIFSLVIAMLLSAGLFIFIPTLVGGAFSKVMPNDFMLNLIEGIIRIAILFAYIVL
                     ISRSKDIERVFQYHGAEHKSIYCYENDLELTVENARKFKRLHPRCGTNFLFIVMAVSI
                     ILFAFFGWPNPILRIFMRIICVPIVAGLSYEVIRVLGKYDNGFTKIIAYPGMMLQYFT
                     TKEPDDEQLEVALEALKAVVD"
     gene            71773..72621
                     /gene="prmC"
                     /locus_tag="PC494_000553"
     CDS             71773..72621
                     /gene="prmC"
                     /locus_tag="PC494_000553"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HDF3911080.1"
                     /translation="MTIKDIIIKYSDKLKDISDTPRLDTELLLQKTLGVDRLYIHLNL
                     NKELTEEQKTKFMGFAEERLNGRPIAYIVENREFMGLDFFVKEGVLIPRPDTETLVEE
                     IIEICREKKDVSILDIGTGSGAITISLAKYIENSKIMSFDISETALEIAKKNAIINEV
                     GEKIKYINSDLFTAISDSNIKFDIIVSNPPYIKKQDIETLHKQVKDYEPYNALEGGED
                     GLDFYRRITEQGKKYLNKCGILAYEVGHNQAEDVINIMKSNGYKKIYTKKDIQGIDRV
                     VIGYNI"
     gene            72665..73729
                     /gene="prfA"
                     /locus_tag="PC494_000554"
     CDS             72665..73729
                     /gene="prfA"
                     /locus_tag="PC494_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HDF3911081.1"
                     /translation="MLKKLEVLEDTYKDLSEKIGDPDVINDQKVWQKYIKEHADLEPI
                     VMKYREYKSVLDSIKESKEILQEESDEELRELAKMELAEMEEKVAPLEEEIKILLLPK
                     DPNDDKNVIVEIRGGAGGDEAALFAGDLFRMYSRYAERRRWKIELLSASDTGVGGYKE
                     VSFMIKGKGAYSRLKYESGVHRVQRIPSTESGGRIHTSTSTVAVLPEVEDVEVEINPN
                     DLRIDVFRSSGNGGQSVNTTDSAVRVTHIPTGEVVSCQDGKSQLKNKEQALKILKARL
                     YDKALAEQHKDIAAERKSQVGTGDRSERIRTYNFPQGRISDHRINLTLYKLDAFLDGD
                     IDEMIDALITVDQTEKMTAI"
     gene            73858..74538
                     /locus_tag="PC494_000555"
     CDS             73858..74538
                     /locus_tag="PC494_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ZIP family metal transporter"
                     /protein_id="HDF3911082.1"
                     /translation="MILKVTIIGLLAGVIGTGLGGVISAIFKREVDKYLSFFMGLSGG
                     IMLAVVVFDLMKESMDKMGIINTVIFTFVGALITMYIKTKLDVSGNMASGYLIFISIL
                     LHNLPEGLAIGSSFMSTESLGITLAIVIGLHNIPEGLAMALGLVCNKMKLSKVILFTV
                     IAGLPMGLGSFLGVYFGGVFTSLIGVFLATAGGTMMYVVLEEIFPHSKSVYCIIGFLL
                     GTMIVNYI"
     gene            74567..75607
                     /locus_tag="PC494_000556"
     CDS             74567..75607
                     /locus_tag="PC494_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HDF3911083.1"
                     /translation="MKTIISNIDINNIDYEEIKIQAKLLREGKTVIFPTETVYGLGAN
                     ALDENAVKKIYEAKGRPSDNPLIVHIYEKEEVYDLAKDISDKAKLVIEKLWPGPITII
                     LNKKDIIPYKTSGGLDTVAIRMPSNVIARAIIKEAGIPIAAPSANISGRPSPTKAKHV
                     YEEMNGRVDGIVLGGDSNFGLESTVLDLTEETPMILRPGSITKEVLEELLGEVKLDPS
                     LSKKEDNQKAKAPGMKYKHYSPNADVYIISGKRENVATKINDMIKSNRDKGLKTGVMC
                     ISRNREFYDGEVIDLGNSLEEVASNLFDALIEMDKKGVDVIYSEEFPKTGVGQAIMNR
                     LLKSAGYKVIKA"
     gene            75624..76073
                     /locus_tag="PC494_000557"
     CDS             75624..76073
                     /locus_tag="PC494_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight protein arginine
                     phosphatase"
                     /protein_id="HDF3911084.1"
                     /translation="MNILIVCTGNTCRSPMAEAILRKAIKESGRSIEEYSISSAGIST
                     ANGMGASENSIEVLKEIGIDLSNHRSKVITKKLIDESDIILTMTKSHKEILVQAVPKC
                     KEKVYTFKGFANKNEEDISDPFGGNLDIYRSTMREIMYSVNEIVKKI"
     gene            76090..76542
                     /gene="rpiB"
                     /locus_tag="PC494_000558"
     CDS             76090..76542
                     /gene="rpiB"
                     /locus_tag="PC494_000558"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose 5-phosphate isomerase B"
                     /protein_id="HDF3911085.1"
                     /translation="MKIGLGCDHGGYNLKKEIISYLESKGIECVDYGTNNATDSVDYP
                     VYGEIVANSVINKEVDYGILCCGTGIGISLAANKVPGIRCAVVSDVFSAKMSKAHNDA
                     NMLSLGERVLGKGLALEIVEAWINTDFEGDRHARRVNMIKSIEEKHNK"
     gene            76578..77207
                     /gene="upp"
                     /locus_tag="PC494_000559"
     CDS             76578..77207
                     /gene="upp"
                     /locus_tag="PC494_000559"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HDF3911086.1"
                     /translation="MSKVVETNHPLIQHKLTLMRDKNTGSKDFRELLTEIAMLMGYEI
                     TKDIPLKDVEIETPIQKTSSKVVAGKKLAIIPILRAGLGMVDGLVSLMPAAKVGHVGL
                     YRDPETLKPVEYYCKLPQDIGERDIIVVDPMLATGGSAVAAIDLLKSKGAKSIKLANL
                     VAAPEGIAEVQKYHDDVDIYVASVDERLNEHGYIIPGLGDAGDRLFGTK"
     gene            77508..78323
                     /locus_tag="PC494_000560"
     CDS             77508..78323
                     /locus_tag="PC494_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EF2563 family selenium-dependent molybdenum
                     hydroxylase system protein"
                     /protein_id="HDF3911087.1"
                     /translation="MKNCIVVRGAGDLATAVIHKLHNSGFKVVALEIEEPLAIRRQIS
                     FCEAVYEKKVTVEGVECIFCNTEKEIEEVLSQHKVALIIDPKGEKLSKLNPIVLVDGI
                     LAKKNLGTTKDMAPLTIALGPGFCAGEDVDVVIETMRGHNLGRIITNGRAEKNTGVPG
                     AIKGFSKERVMHSQYDGIMENVCKIGDIVEKGDLLCYINNYEKKHEVRATISGVLRGL
                     LKDGAKVNKNLKILDIDPRKEEVKNAFTISDKARCIAGGVLEAILNNGIYPQN"
     gene            78549..78986
                     /locus_tag="PC494_000561"
     CDS             78549..78986
                     /locus_tag="PC494_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dCMP deaminase"
                     /protein_id="HDF3911088.1"
                     /translation="MRPSWDEYFMEIAEVVKKRSTCIRRQVGAVIVRDKQILTTGYNG
                     SPRNLEHCENIGCKRQELNIPSGERHELCRALHAEQNAIIQAAHNGISVDGATLYVTT
                     RPCVLCAKMCINAGILKIVYEGDYPDDMSTELLKEAGIELIKF"
     gene            79171..79398
                     /locus_tag="PC494_000562"
     CDS             79171..79398
                     /locus_tag="PC494_000562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AtpZ/AtpI family protein"
                     /protein_id="HDF3911089.1"
                     /translation="MSKRNTHTEIAKLFSLISQIGLMIVISILGCTFLGKFLDSKLNT
                     TPVLTIIFLLLGVGGAFSGVYKTLIVYTRRK"
     gene            79403..79789
                     /locus_tag="PC494_000563"
     CDS             79403..79789
                     /locus_tag="PC494_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase subunit I"
                     /protein_id="HDF3911090.1"
                     /translation="MDIKLLNQVRSVTKGIVIFDVVLIVLMLITSTLSKPVLLGLIFG
                     SIIAMLNFRLLAISLEKSVTFPAGKAQAYASAQYAVRLFIMAVVLIASATVPHLNIIG
                     TALGLLSTKFVILSKNFINKLKRKEA"
     gene            79792..80496
                     /gene="atpB"
                     /locus_tag="PC494_000564"
     CDS             79792..80496
                     /gene="atpB"
                     /locus_tag="PC494_000564"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HDF3911091.1"
                     /translation="MNQAHYYLIGNFKISETILVSWGIMAFLAIASYFLTRNLKKVPT
                     SKVQIFLEFAVGGLAKMVTDVMGKNTVKRMPYMIPYIGSLFLFFACSNLSPLLGLRSP
                     TTDLDTTAAWAMITFFMIYFAGVKFKGLSYFKELAQPLAIMLPINIIGELARPISLSF
                     RPFGNILGGTIIMGLFYQLLGFISSLIPGLSIPIGEILIPVPLHLYFDLFAGLLQAYI
                     FIMLTMVFISSAGELD"
     gene            80565..80825
                     /gene="atpE"
                     /locus_tag="PC494_000565"
     CDS             80565..80825
                     /gene="atpE"
                     /locus_tag="PC494_000565"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase F0 subunit C"
                     /protein_id="HDF3911092.1"
                     /translation="METAIVAAASAIGAGIAVATGIGAGIGQGIAAAKAAEAVGNQPE
                     AKGDITSTLLLGVAIAESSAIYGLVISIILLFVNPFFKYLGM"
     gene            80948..81445
                     /gene="atpF"
                     /locus_tag="PC494_000566"
     CDS             80948..81445
                     /gene="atpF"
                     /locus_tag="PC494_000566"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HDF3911093.1"
                     /translation="MEKALVGITWEFVFQIVNTFIIFLLLRKLLFKPVLNIIESREND
                     IKSDLAEGEKAKNEGLALKKEYESKINFAKDEGQEIIKQATIRAEQKSDDIVNTAKKD
                     ALDIKEKANKDIEQERQKVINEIKNDISNIALLAASKVIEKDLDKSKHEELIENFIKE
                     VGEAK"
     gene            81442..81987
                     /locus_tag="PC494_000567"
     CDS             81442..81987
                     /locus_tag="PC494_000567"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HDF3911094.1"
                     /translation="MINVIANRYAEALFQLGEEENSTDVLFKELEKVVDMMTKVSKDF
                     YKVLKSPLVSKSEKKNLVEIIFSKEVSSNIKNFLKVLVDKDRISYLEDIELAYKELLN
                     KKNNVIDGVAISAIPMSETDIKELEVKLSNKYNKNVTIENVVDKTILGGVLVRIGNEQ
                     IDGTVKTRLDKMKEKLSEVIS"
     gene            82004..83506
                     /locus_tag="PC494_000568"
     CDS             82004..83506
                     /locus_tag="PC494_000568"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003405060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HDF3911095.1"
                     /translation="MNLKPEEISSIIKQQIKNYENKVELTDTGSVLTVGDGIASVYGL
                     EKAMSGELLEFPGEIYGMALNLEEEVVGAVILGDDSEIKEGDIVKRTGRIVEVPVGEA
                     LIGRVVNSLGQPIDGKGPIAYTKTRPVESEAPGIIDRRSVYEPLQTGIKSIDSMIPIG
                     RGQRELIIGDRQTGKTSIVIDTILNQKGKDVICIYVAIGQKRSTIAQLVSSLEKGGAL
                     DYTIVVSATASESAPLQYIAPYAGAAMGEEFMYNGKHVLIVYDDLSKQAVAYREMSLL
                     LRRPPGREAYPGDVFYLHSRLLERAAKLSDELGGGSMTALPIIETQAGDVSAYIPTNV
                     ISITDGQIYLQPELFYSGVRPAVDPGISVSRVGGSAQIKAMKKVAGTLKLAYSQYREL
                     AAFSQFGSDLDEDTKKRLAQGERIVEILKQGEHQPIKVENQVMIIYAVINNHLEDIPI
                     DNIARFESELYAFVDNNYPEISRKILGGEDFTHDLTDAINEFKEKFVVEV"
     gene            83534..84412
                     /gene="atpG"
                     /locus_tag="PC494_000569"
     CDS             83534..84412
                     /gene="atpG"
                     /locus_tag="PC494_000569"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase F1 subunit gamma"
                     /protein_id="HDF3911096.1"
                     /translation="MAGAGIKAIKTRMGTVESTKQITKAMELVASSKLRKAKEKAEDS
                     REYFNTLYNTVKDIAQTTRGIRNEFLKEREVKNKCYVVVAGDRGLAGGYNSNVLKESV
                     SHMKGKKETVITVGKKAHEFFSKRNYNIAKDINSVEACGYEDATEISQTIIDLYKKGE
                     VDEVYIAYTKFKSALSQEVEILKLLPLVFEKDTDEQGMAVKEEKQNRSKVQYIPSAEA
                     VLSYIVPQFISGTVYGGILESFASEQGARRTAMESATDNANEMLSNLELSYNRARQSA
                     VTQEITEIVGGVEALK"
     gene            84425..85819
                     /gene="atpD"
                     /locus_tag="PC494_000570"
     CDS             84425..85819
                     /gene="atpD"
                     /locus_tag="PC494_000570"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HDF3911097.1"
                     /translation="MANVGKVVQIVGAVLDVKFDGEQSLPNLLNALVIKLGDKEIVAE
                     VAQHIGDDTVRCIAMSATDGLVRGMEVVDTGGPISVPVGDETLGRIFNVLGKPVDGKP
                     APKSAPKLPIHRPAPAYDELETTAEILETGIKVVDLLAPYLKGGKIGLFGGAGVGKTV
                     LIQELINNIAKQHGGISVFSGVGERTREGNDLYGEMSESGVINKTALVFGQMNEPPGA
                     RMRVALTGLTMAEHFRDEQGQDVLLFVDNIFRFTQAGSEVSALLGRMPSAVGYQPTLA
                     TEMGALQERITSTKKGSITSVQAVYVPADDLTDPAPATTFSHLDAKTVLSRQISSLGI
                     YPAVDPLESTSRILDPSIVGKEHYEVARGVQSILQRYKELQDIIAILGMDELSDEDKL
                     IVARARKIQRFLSQSFTVAEQFTGNPGQYVPVKETVRGFKEILEGKHDDLPESAFLFV
                     GTIEDAVRKAKGSM"
     gene            85822..86082
                     /gene="atpC"
                     /locus_tag="PC494_000571"
     CDS             85822..86082
                     /gene="atpC"
                     /locus_tag="PC494_000571"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase F1 subunit epsilon"
                     /protein_id="HDF3911098.1"
                     /translation="MASEFSLKVVTPSNTFYDGDVEMIVVRTTKGDKGVLKGHIPFVS
                     GIPVGTLKIKKEGSFKEAKIAEGFINVTQDKTVILTESAEWI"
BASE COUNT        34791 a         9332 c        15859 g        26377 t
ORIGIN      
        1 tattaaaaac ttaatagaaa tattaagcat aaagattatg tggttacaat agcagagagg
       61 atacacctgt tcccattccg aacacagaag ttaagctctc tagcgctgat ggtacttggt
      121 gggaaactgc ctgggagagt aggacgtagc cacgtaattt tttttatttt ttgtcaaaaa
      181 aaacaaaaaa tacgtatttc ttttttcatt tcgggaaaac taaacacagg aattatggac
      241 tttataaaaa tttaattctt gaggagtgat ataagtgaaa aaagttgctt taattttagc
      301 tataataggt gcgcttaact ggggtgcaat tggtattcta ggtacagact taataggtag
      361 tatctttggt ggaacatatg aaatggtaag tagaataata tacttcattg taggtttagc
      421 tggattatac ttaataccaa gtttaatgtc tgatgataga gaataattta tgcttttatg
      481 ttaaatacct cattctaaat gtttagaatg aggtatttaa ttttataaaa atattaattt
      541 gtttcttttt taatggtaaa atagataaga attgaagttt taaaaagaag tattatgtaa
      601 aaaaggagta ctattaatat atgtttatta ttaatgaatt aaataagatt gtaaatgaag
      661 aagtaatatc ttttcatatg cctggtcata aaaagggaca ggtttataaa aagttaggat
      721 ataaagatat actaaaaaat ttgtataaaa tggatacaac tgagatatta ggaacagata
      781 atttacactt tccggaagga attataaaaa attcacaaaa aaaagcatca agagtattta
      841 aaagtgatta tacttgctat ttagtaaatg gtagtagctg tggaatacaa tctgcaataa
      901 tgtcagtatg tagtcctaaa agtaaaataa taacaaatag agactgtcat cagtctgtta
      961 taaatggatg tattttagga gatatagata tagagtatgt gccttgtgag ataagtgaag
     1021 agacaaatgt cttaaaaggg atatctataa gtaatgtgat tgatataata gataaaaact
     1081 tggatgcaaa agcagtactg cttacttatc ctacatatta tggaatgaca tatgatttag
     1141 aatacatatg taattatgca catagcaaaa agatggtagt gatagtagat gaagcacatg
     1201 gtgcgcattt agggcttagc gagaggcttc ctaaaacagc tcttgagcaa ggcgcagata
     1261 tagttgtaca gagtacacat aaaactcttc cagcatttac acaatcgtca atgatacata
     1321 tacagggaga ccgagttgat atagataaaa tattgaacat gttaagaatt acagaatctt
     1381 caagcccttc atatttatta ttatcttctc tggaattagc agtagatata tatgaaaata
     1441 aaggaaaaga attaatggaa gagcttttaa ataatattat aactttcaaa aataaagttg
     1501 attcaaatat taatatatac gacacaaatg ataaaacaaa aatatttata tcatctaaaa
     1561 atatgggttt aacaggttat gaactagaaa atattttaag aaacaaatat aacatacaag
     1621 tggagttatc taattattat ggagttcttt taatatgtac aataggaaat actgttgagg
     1681 atttctctag tttagaaaca gcattaaaca atattgtaaa ggaagacttt aaatttgaaa
     1741 agttagaaaa taaaaaatac cctgttgtta ttccaaagaa aatattaaca cctagagaag
     1801 cattttataa aactaaaaaa agtgttaaaa tatatgacag cataggtaaa gtttgtggtg
     1861 aatgtatagt tccataccca cctggaataa gtgtaatatc tcctggtgaa gtaataagta
     1921 aagaaataat agactatcta atgttttgtc attctaaagg catgattgtg agtggattga
     1981 aagatgtaga tttaaatttt atacaaataa tagatttaga agacatttaa aaattatgat
     2041 ataaaagtag atagaagtag atagtttaaa attgtgaaga gaaataaata gactgcttat
     2101 atagagctat ctaataaaag tactaaaaaa gtaaaaagtg tttgtatgga ggatatgaaa
     2161 atgaaaggta agttaataat tatagagagt ggttcagatg caagtggaaa ggctactcag
     2221 acagaaatat tatatgaaag attaaaaaaa gaaggctata tgattaaaaa ggtagaatat
     2281 ccaaattatg aatctccatc atctgccttg gtgaaaatgt acctaaaagg agactttggt
     2341 aaaaatgcat cagatgtaga cccatatata gcatcaactt tttttacagc tgataggtat
     2401 gcatcattta aaaccgattg ggaggagttt tacaatgaag gtggaataat tatcgcagat
     2461 agatatacaa cctctaatat ggtacatcag gcctctaaaa tggatatttg tgatagagaa
     2521 gagtatttaa attggttagc tgattatgaa tttaatttat ttaagatacc acaacctgat
     2581 tgtgttatat ttttagatgt gcctattgaa tttagtaaaa agcttatgga gaatagaaaa
     2641 aataaaatta caggggaaga aaaaaaggat attcatgaaa gtgacataga gtatttagag
     2701 aaatcttaca acaatgcttt atatatagca gataaatatg attggaaaaa aataaattgt
     2761 gttttagata acaaattaag aagtattgaa agtatacata atgaaattta taaaatagtt
     2821 cttgattcaa taaaacctat ggagagataa atatgtattt tgaaaatatt atagggcaag
     2881 attttgcaaa gaaatattta acaaattcta taaagaaaaa taaacttaat aatgcgtata
     2941 tgtttgaagg aatggatgga ataggaaaaa agaaatttgc agatgaatta tcaaaactat
     3001 tacttgatta tgaaaatctc gaaaatagtc cagactatgt actcataaaa ccagatggaa
     3061 atagtataaa aatagctcaa atcagaaatt tacaatcaga tatagtaata agacctcata
     3121 aagactataa aatatatata atcaataatg ctgaaaaaat gactgtggaa gctcaaaatg
     3181 cacttttaaa gacgctagag gaacctccaa actatgctat aataatctta gtcacaaaca
     3241 acaaggaatc tttattagaa actataaaat ctagatgtga tataataaag ttctcaccta
     3301 taccaattga agacttaaaa cgttatttga taaatacagg tatagaagaa gaaagagctc
     3361 aattattggc tattttttcg agaggaagta ttgagaatgc tctaaatcta tctcagtctt
     3421 ctgagttttc aatgatgaga gaagatatac aacagtatat tcagataatg ttagataaaa
     3481 acatagtgga gattttaaat ataccaaata atatggaaaa atatagaggt aagattatag
     3541 ctttattaga tatgatgata aactattttc gagatatcat cctattaaaa gaaaatgtaa
     3601 acaagaacat gttaataaat gtagataagc tagttttcat tcaaaatatg agtggaaaaa
     3661 ttagttattc tcaattgtcc aagattattg atataataga agatgcaaag agtaaaataa
     3721 aaagcaattg caatttcaat ataagcatac aagttatgtc tttaaatata tacgaggtga
     3781 ttaaatgata aagatagtag gtataaggtt taaaagtgct gggaaaatat attattttga
     3841 ccctgttgat tttaatatag agcaagatat ggatgtagtt gtagaaactg caagaggctt
     3901 ggagtatggg aaagtagtcg ttggtccaaa agatatggat gaaagcgaat tagtttctcc
     3961 tttgaagcca attataagaa tagctacaga agaagataaa aaagtatatc tagaaaataa
     4021 ggaaaaggca aaagaaactt ttgagttgtg ccaacaaaaa ataaaagaac atgagttaac
     4081 aatgttttta atagattgtg agtatacatt tgataggaat aagttgattt tttactttac
     4141 agcagaagga agaatagatt ttagagaatt ggtaaaagac ttagctgcta tatttaaaac
     4201 tagaatagaa cttagacaaa taggtgtcag agatgaagct aaatctatag gaggtctagg
     4261 gccttgtggt agaaaacttt gttgttcatc ttggttaggt gattttcaac cagtttcaat
     4321 aaaaatggca aaagaccaaa gtctatctct aaatccaaca aaaatatctg gaatatgtgg
     4381 gagattattc tgttgcttaa aatatgagca tgatgtatat agtgaagcaa tagaaaaaat
     4441 gcctgttgta ggtgcattgg tgcaatcaga tgatggaaaa ggaaaagttg tagaagtgaa
     4501 tcctttatta gaacaaatta aagtggaatt tcaagacaag acagtaaaga tatacacaag
     4561 agaagatata aaaatactta gagagcctaa aaaatgtgat ggctgtggtg gtaaatgtaa
     4621 ggataatgat ggattagatg aagccacact aagagagcta aagaaattag aagattaaat
     4681 ttaaggtagg gcttttccta ccttttttaa agcaattaat gcttaaagtt attaatattt
     4741 gaggagaatt tatatatgca attaaaagat tcagaaagaa tagatgattt acaattaaaa
     4801 ggtcttaaaa ttatacaaga tactaatggt ttttgttttg gtatagatgc agttttatta
     4861 gccaatttta ctaaaataaa aaaagatgcc aaagtagtag atttgggtac tggaactgga
     4921 attataccta ttttgatagc tggaaaaagt gaagctaaaa aaattattgg cgtggaaata
     4981 caagaagatg tatatgaaat ggcaactcgt tctataaaat taaatggatt agaagaaaga
     5041 gttgagatta taaatgaaga tataaaatac atagacaaag tcttagacat aaatggttac
     5101 catgtagtca catcaaatcc tccatatatg catattgatg gaataaaaaa tccaaatgat
     5161 aaaaaagcaa tatcaagaca tgaagtaagg tgcaatttgg aagatgtaat tagagctgca
     5221 tccagattgg ttatgcctag aggaaaattc ttcatgatac atagaccaac aagattggtt
     5281 gatataataa ctttagggag aaaatataaa ttagaaccaa aggttattca atttgtgcat
     5341 ccaagacctc aaaaagcacc gaacttagtt ttggttcaat ttgtaaaaga tggaaggcca
     5401 gagcttaaaa tattggaccc attgtatgtt tatggagaag atgggaatta tacaaaagaa
     5461 ttaaaagcaa tatataataa taaagatata ggagagttgt aaatgagcgg gaaattgtac
     5521 atatgtccaa caccaatagg aaacctagaa gatataacat atagaacttt aagaacatta
     5581 aaagaagtag acttgattgc agcagaagat acaagacata gtataaaact tttaaatcat
     5641 tttgaaatct caaaaccact aactagttat catgaacata ataaggattc aaagggagat
     5701 tatttgataa ataaactaat tgatggtgaa aatatagctc tgataagtga tgcaggtatg
     5761 cctggtatat ctgacccagg agaagagata ataaaacaag ctatacaaaa taacatagag
     5821 atagaagtat tgccaggtgc aacagccttt gtaacggctt tagttggctc tggtatggac
     5881 acacatagat ttgtttttga gggcttttta gatagagata aaaaagttag gaaagcacaa
     5941 ttggaagaat taaaggaaga aagtagaact ataattttct atgaatcacc acatagattg
     6001 aaggatacac taaaagatat gcttaaaatt cttggtaata ggaatatttc tataaataga
     6061 gaacttacaa aaaaatatca agaaataata agagaaaata tagaaactac cataaaaata
     6121 tttgaggaaa aagaagtaag aggagaattt gtattaatag tagagggttt tcatggtgag
     6181 aagtcaaaga aagaaaatta tgatgggctt acagataggg aatatgtttt aaaactaatt
     6241 gaaagtggta tgaacaaaaa agatgcaata aaaatagttt gtaaagatag aaagttaaag
     6301 aaagatgtgg tttataaaca agttttagat ttataaaacc tgaatctgag gtgattttat
     6361 ggaaataggg aaaattataa tagagagttt aaagagggaa gatacacata aaatatttat
     6421 agaattagat aataagcatg aattagaaaa aataattcct aaaataagct gtatgaagtc
     6481 tgtaggtgaa tgtaaatatc atgtagtaaa ttgttttgaa cattctataa acgcattaaa
     6541 agaattagaa atagtattaa atgataagga tttttttcca atacatctaa gaaaacatgt
     6601 gtcaaactat ttaaacacat atattgaaga aggaataaat aagttacatg tattaaagct
     6661 gggaacattt ttacatgata taggtaagcc tgacagtatg accttagatg aaaccggaag
     6721 agttcatttc acaaatcatg aaaaaatagg tgctcaaata attgacaata tgggaataaa
     6781 gttagagtta tcaacagaga catatagact tataagtaaa tatgtaagat atcatatgat
     6841 acttttgtct ctatataaga aaaatgattt gagtaggaaa gaattaatta atgtatttaa
     6901 cttagtagat gaggatacta taggtgtaat aatgcttggg tatgcagata tagtgtctac
     6961 agtaaaatta ttgggcaaga gtggagaagt cagtgtgtta aagacatata tggaatatat
     7021 tttaacaaat tacttgtata agagtaatta tacacatgta taaatttagt taatataatt
     7081 gaattttaga tgattaattg aagtttgaaa tatacggatt tcaaaaacat aaaagaagtt
     7141 gtctttgttg taaaattatg aaagacaact ttttttatat caaaaattga aattttatta
     7201 aggatactta atggtctatt aattaataaa ccattagtat ttaatttata ttacaatatt
     7261 gattttgctt gtattggcgt tgatagtata acagaggtct tagtagaacc aattttcttt
     7321 atagtatcaa tcacattttc tagctcgtac atatctttta caattacttt taaaagtaag
     7381 caatcatcac ctgttatatg gtgacattct acaatcctag ggtcctttgc agctgactca
     7441 ataaattctg tatatccatt gcttggaaga gaaatatgaa taaatgcctt tataactctg
     7501 cctaatgaat ctgggttgac aatagcttta tatccttcta taacaccaga ctcttctaat
     7561 cttttgactc tttctgaaac tgcaggagaa gttaaaccaa ctatttttcc taagtccttc
     7621 atagaaattc tcccatcatc ctgtaaaatt tctatgattc tgtaatctgt aacatccata
     7681 aataaacagt cccccttaaa taaaaataat taatgctata aaactttttt agaatctatc
     7741 atttgtgttt ttaaatacca aagatttcta gataaatcaa ccttataaat gtgtggtttt
     7801 gaaagtcttt tgtattgttc ccagatagta cttaattcat attgtacatg attttttatt
     7861 tcaagaacag cttttttatt atatttgcat ctgcctttta tatacaatgg tttaagaagc
     7921 tctttaactt tgtaatttgt aaataccttc gttttccatg tataagtagg atggaagatt
     7981 tctaaaggtt tagactcatc tataacttca tcatgtaaca taatcaaatc tgcctctgcc
     8041 ttattgtctt cgttatatat tcttataact ttcttgtaac caggattatt tattttttct
     8101 ggattctcag aaatctttat cttaggttca agaactcctt tttcacaaga tgcagctaat
     8161 ttataaactc ctccaagaga aggtgaatcg aaagatgtaa tgagctttgt acctactccc
     8221 catgaattta tagtagctcc ttctgcttta agtgatgtta tggtatattc gtctaggtca
     8281 ttagatgcag tgatgctgat atctgaaaag ccagcattat ctaattgttt tttagcttct
     8341 ttagataaat aagctaaatc tccagagtca agtcttatac ccataggttt gtatcctttt
     8401 tcagaaatat ttttgaatac ttttattgca ttaggaactc cactgtttaa tacatcataa
     8461 gtatctacaa gtagtaggca tttatctgga taaacatcag catatgcttg gaatgcttca
     8521 agttcattat caaatttttg tacccaactg tgagcttgtg taccaattat aggtatatca
     8581 aacattttcc ctgctagtac gtttgcagtt ccagcacaac caccaactac agcagcccta
     8641 gccccatata tccctgcatc tggaccttgt gcacgacgta atccaaattc aaatacaggg
     8701 tctccttgag ctgcaaagca aactctagag gctttagtag caataagaga ctgaaaatta
     8761 actattgtta acaatgctgt ttcaataagt tgagcttgat ataaaggtgc cttaacagta
     8821 attaatggct cattagggaa catgatagtt ccttcctcaa cagcatatat atctcctgtg
     8881 aatttaaatt cttttaaaaa ttttaagaac ttgtcagaaa ataaatttaa gttttttaag
     8941 tactctaaat cttcatctga aaaatgaaga ttatctatgt attcaacaac ctgatcaata
     9001 ccacaaacta tagtataccc tccatcacaa gcgttttttc taaaaaacat atcaaataca
     9061 acaatgtctt catgaatatt cttttcaaaa tagccattta acatagtaag ctgatataaa
     9121 tcagtaagaa gtgttagatt tctcattatt tctctcctta attattatta aatattaaaa
     9181 attgtaaaaa ctcccacact tatactaaaa cataatatag tacaactttc aagtataaag
     9241 tattacctaa ctatcataaa attatttaaa gaggaggatg attataatag gaaaaatatg
     9301 gttttatatg gtatcgatag gaataatagg aagcttgatt tctaaaaata tgggtgaatt
     9361 aaataaagtt atattaagtg aaacatcaaa aggtatagag tttgcaataa gtctagctgg
     9421 tatcatggca ctctggatgg ggataatgaa tatcgcaaaa gaatcaggtt taattgaaaa
     9481 gataggtcaa aaactaaatc ctataatgag aagattattt ccttctattc caaaaggtca
     9541 taaagcaatg tcttatatag ttatgaatat tgctttaaat atgttgggtg ctggaaatgg
     9601 tgcaacagca tttggtttaa aagcaatgag tgagcttcaa actttgaata acaagaaaga
     9661 tacagccact aatgatatga ttatgtttat ggtaatcaat atatcatcta tacaaataat
     9721 tccatttact ataatcaaac taaggatgga tatgggggct caaaatccaa gtgaaataat
     9781 ttttacgact ttatttgcaa ccataatatc tacagcagta gcaataataa catgtaaatt
     9841 ttttcaaaga agatatagat aaaggggatg tagatacatg gagatatttt caaacttact
     9901 tataccaata ataattctgt acatagtagt ttatggtaaa tataaaaaaa tagatgtgta
     9961 tgatagtttt gtaaaaggag caattgatgg gttaaaagca gcatgggata tcctaccata
    10021 tataataggt atatttttgg caataggaat attcaaaact ggtaaaggtc ttgatatgtt
    10081 agaatggcta tttacaccaa tagcaaatat gatgagtata ccaaaagaat taataggtct
    10141 aataagtgta aaacctttat ctggaagtgg tgctttaggg atgtacagtg aacttgcaaa
    10201 tagagttgga ataggaagtt tagtagaaaa aatgggtgct acgattgtag gttcttctga
    10261 gactattttt tacacaatgg caatatacta tggaagtctg aagataaaaa atactagaca
    10321 tacattatca tgtgctatga ttagccatgt tgcaggtgtc atagcagctg tttttatttg
    10381 ctatgtaata tttgtataat ttgttgacaa tatgggaaaa attttataat atagtgatta
    10441 tatagaaaca aatagtaata caaattacaa gctatgaaaa gaagagtaaa taaaggtttt
    10501 ttctatcaga gagctaggtt aggtgaaagc tagtgtcaaa agctttattg aagatggtct
    10561 tggagctttt tatctgagca agtgtgctag ggtaaaacgg ttggacacgt tatagtctac
    10621 taaggtatct ataaaatgtt tctacatttc atgtgaaaca taactattat agatgaatta
    10681 gggtggtacc gtgaataatc tcgcccctat gttaactcat aggaggcgat tttttattat
    10741 ttaaatgaaa gaatcatatg attacgaacg ataaaaaatt aggaggtaaa taacatgagc
    10801 aaaccgagtt tttatgtaac aacaccaata tactatccaa gtggaggatt acacatagga
    10861 catacttatt caacagtagc tgcagataca atagctagat tcaagcgttt ctgtggatat
    10921 gatgtaaagt tcttaacagg aacagatgag catggtgaaa aaattcaaaa gaaagccata
    10981 gaacaaggaa tgtcagagat agagtatctt gatggaatga taaaagatat aaaggcctta
    11041 tggaatacta tggatatatc ttatgatgat tttataagaa ctacagaaaa aagacataca
    11101 gacataatac aaaagatatt tactaaacta tatgagcaag gtgatatata taaaggtgaa
    11161 tatgaaggta gatactgtac tccttgtgag agtttctgga cagaatctca attactagaa
    11221 ggaaataaat gccctgactg tggaagagaa acatatttag taaaagaaga atcttatttc
    11281 tttagattat ctaaatatga agacagatta aaagagttat ttaaagatga tagtttctgt
    11341 tttcctgctg ctagaaaaaa tgaaatggtg gcaaactttt tagacaaagg attagaagat
    11401 ttaagcgtaa ctagaacgac ttttgactgg ggtataaaag ttccttttga tgaaaaacat
    11461 gtaatttatg tgtgggtaga tgctttatgt aactatataa cagcattagg ttatatgact
    11521 gataatgatg aagaatttaa aaaatattgg cctgccaatg ttcaaatagt aggtaaagaa
    11581 atagtgagat tccatacaat aatatggcca gcgcttttaa tggctttagg tctagaagtt
    11641 ccaaaacaag tatttggaca tggatggata ctatttgctg atgataaaat gagtaaatca
    11701 aaaggtaatg tggtttatcc agaacctata atagaaagat atggaataga cacacttaag
    11761 tacttcttat taagagagtt tgcatttggg caagatggaa gttatactca tagaaatttt
    11821 gtaacgagaa taaattatga tttagcaaat gatttaggaa acttaataag tagaactgta
    11881 gctatggttg aaaaatacaa taatggtata ataccaacag caaaagtttc aactaatttt
    11941 gatgctgact taaaagaaca agctgtttca actagagaaa actttgaagc tgaaatggat
    12001 aaaatgcaat tccatgaagc attagagagt gtatggaaat tagttagaag aactaacaaa
    12061 tatatagatg aaactatgcc ttgggcacta gctaaagatg aaactaagaa agatgaatta
    12121 gacacagttt tatataattt atgtgaatct ataagaataa tcgcaacact aataaatcct
    12181 ataatgaatg agactgctaa taaaatatat gaacatatag gaataaaagg tcaagatgat
    12241 ataactacat gggaaagtac aaaaacattt ggtcttattg gagaaaatgt aaaagtattt
    12301 aaaggtgaac ctttattccc aagattagat gtagaaaaag agatagaaga attaactaaa
    12361 atgttctctg ggaaacctcc agtagaagaa aaacctttag agcataaaga agaaattact
    12421 attgatgatt tagacaaaat agagcttaga gtagggaaaa taataagctg tgaaaaacat
    12481 ccaaaagcga ataaattatt agtatcacaa gttaagattg gaccagaaac aagacaaata
    12541 gtatcaggaa tagctgaata ctataagcca gaggatttag taggaaaaga ggttacagtg
    12601 gtatgtaact taaaaccagt taaattaaga ggtgtagaat ctcaaggtat gatattagca
    12661 gcaggtgatg atggagaccc atatgtttta ccatttacac aaggggctaa agatggatgt
    12721 gaggttcgtt agtaggtaat taaatagtaa ggagattaaa gatgttattt gactcacatg
    12781 cacatttaaa tgatgaaagt tttgatgaag atagagatga acttattggt tcattaaaag
    12841 ataaaggtgt agatttggtt gtaaatccag gagcagatat agagacgtcg ataacagcaa
    12901 ttgaacttgc gaaaaaatac gactttatat attcagcagt tggggtacat ccacatgatg
    12961 tatcaaaact agatgataca gcaatagaaa ctctaagaaa acttgcaact gagaatgaaa
    13021 aagttgtagc tattggagag attggattag attattatta tgattattct ccaagagaag
    13081 aacaaaaaga gtggtttaag aagcaaattg aattagctaa tgagctaaaa cttccaataa
    13141 taatacatga tagagatgca catggagata cttttgagat aataaagaat actaaaaatc
    13201 ctgaaatagg atgtgtactt cattgttata gtgggaatgt agagttagct agagaatatg
    13261 ttaagatggg ttgttatata tcaattccag gtacggttac ttttaagaat aataaaaaaa
    13321 ctagagaagt agtaagagaa atacctctag aaagattatt catagagact gattcaccat
    13381 atatgtcacc agagccacat agaggaaaga gaaacaatcc ttctcaagta tcttttgttg
    13441 ctgataagat agcccaggaa aaagggatat cttatgaaga agtatgtaga gttacaaaag
    13501 aaaatgcaaa gaaatttttt aatataaaat agacaaatta aatcttataa tgatatatat
    13561 aataagtcat tataagtata ggatgagagt gcctcaaaat gagtttttta gtttatgagg
    13621 cactcttttt gtatgaaatc aaatatattt tcatcatttc aacaatgaaa aagaagttta
    13681 tcatattttg agatagtttg tttttattta tttaattcat attttaaaat atattttctt
    13741 aacattgtta aaaaagaatt tacaagatat tcattagaat taactcaact ctaatattca
    13801 cttaacttaa gttgtttatt atattattaa agagaagtaa acgaaaagta gattaaggag
    13861 gttgaatttt gtatacagtt gatagtacta agatattgat aaatatgaac ttagagaaac
    13921 tagaaaagat atactcaatg ataaaagata catcaagtat ttctataatt aaagaaccta
    13981 acttggctac agtaatggta agagctaatg aaagtgtaaa aaacacaaca tttaatttag
    14041 gagagatatt agttactgaa tgtagtgtaa aggtagatga aagcttgggt tacggaatag
    14101 tttcagaaaa caataataag aaagccattt atttagcagt tatagatgca gttttacata
    14161 gcaataacag taaatttgat gagttaaaga attacataaa taaaagtgta tatgaagaga
    14221 acttaaggta tgaacaagag attattgatg aatttagctt gattaataaa acgaaagttc
    14281 aattcaatgc tatggattaa ataggaggag aatcatggta aattatacac aagaaatata
    14341 tagaaagatg ctagatagtg cttcatttcc tgggaaatta aataatatag ataatataaa
    14401 tatagaaaat aatacaaaac tattgaatgg agcaattggt atagcaatca ctttattaga
    14461 ccaagaagtt accttctata tagaaaatta tactcaaaaa gatataaaaa atataagagc
    14521 acttacaatg tcaaatcaaa tagattatag aaaatcagat tatatatttt tagatattaa
    14581 ttcagaagtg gatatattac agattaaaat aggttctttt gaatatcctg atgaaagtgc
    14641 aactatagta catcaagtaa atgatttatc aacgtactct caaactaagt atataaagct
    14701 tgatttgagt ggtcctggta taaaatctaa aaatagtata tatataaatg gaattagaga
    14761 agaatttata gaaagattat ctagcataaa taaagattat ccaataggaa tagatttgat
    14821 tttagtagat aaaaaaggag aaattgcatt tataccaagg tcatcaaaat taagttggga
    14881 ggtattatag aaatggctta tgtagcagtt aaaggtggag aagaagccat attacaggct
    14941 aaaaatatac ttgagtttta tagggtaaaa ggagatagct tgcctataga tgtaaagcag
    15001 attgaggaac aaatgtctta tgctgtagac aaagtaatgt ctgaaggaag tttatacaac
    15061 aaggaactat cagcattggc tataaaacaa gctcaaggtg atatattaga agcctctttc
    15121 tatgtaagag ctttaaggtc aacaatgcct agaattacat attcagaacc cataaataca
    15181 gaagaaatga gaataaaaag aagaatatca gctactttta aagatatacc aggaggtcag
    15241 tatcttgggg caactagaga ctatgaaaat agaatattga atgtagaatt attagaagaa
    15301 gatgaaaaaa agaatagaca ttttagagat agttttataa atgaattaga aacagtagat
    15361 gaaatccctg aatttacaaa aatatctaat atatttagaa aagaaaattt attacaagaa
    15421 gaagtttgtg aaaacaaatt ggaagaagtt attgatgata ttacaagaaa tagtttaaga
    15481 tttccagttt ctaggtcagc aaagttacag gcattaacta gaggtgaaag tggagtagtg
    15541 tcaggttttg cttatgctat tgtaagaggt tttggtgatg aacatccata tataagtgaa
    15601 cttagaactg gtaatgtatt tataaaagta aaacatccca tctatgaaga tgaagaaata
    15661 ataatagggg atatgctggt tactgaatgt gaaatagttt caaaagcatc acaaaataag
    15721 actgaaaatt ctaaaactaa ttcggaagat aaaaataaga tgtctttagg atatggtctt
    15781 tgtatgggga ataatgagaa taaggctata tctatggcca tactagacaa atctttggag
    15841 ccaaatagtg aaaaactagc acaagatgaa gaatttgtat tgcttcatat agatggaata
    15901 gattcattag gatttatatc tcactttaag cttcctcact atgtagattt taaagcggat
    15961 gtagaaagaa taaaatagtt tgaggaggta agtttaggtg atatataact atggtttttt
    16021 agacgaaaac acaaaaaaag aaataagaag aaagatatta aaagcaatat caatacctgg
    16081 ttatcaagtt ccctttggtt caagagagtt gcctatagct aagggatggg gtactggagg
    16141 tttacaatta acactatcat taattggtaa aaatgatgta gtaaaagtaa ttgaccaagg
    16201 aagtgatgat tctacaaatg cttgtaatat aaggagcttt attgcaagtg taagtaatgt
    16261 agaaaccaca aaagatacat tagaagctac attgattcaa acgagacata gaataccaga
    16321 agaaaaactt aaatctaatc aaatactaat atttcaagta ccaataccag aaacccttag
    16381 aatagtagaa cctagtgaag tagaaacaag aagaatgcat tcagaagaag attatagtag
    16441 gatgtgggta tatctttatg aagatatagt tagatttaat gatatatcta tagcagttga
    16501 atatccatgt aaagtaaatg atagatattt aatgaatcca tcacctatac ctagatttga
    16561 tataaaaaaa ttaaatatgt cagacaattt attcttgttt ggtgcaggta gagaaaaaag
    16621 aatttatgct attcctccat atacaaaggt agaaccttta gagtttgagg attataagtt
    16681 tgaagaggaa aagtttgaag gaaaatactg tagtttatgt aacagtacaa atacattttt
    16741 agatgaagta tatgacagtg acactaatga aaagtactat agttgctcag atacaagtta
    16801 ttgtgaaaaa gttagattaa aaaataacag tatagatgtg acaataggag gtacttggaa
    16861 tgagtaaaat aaatgactct aaaagattag aaaatataga caagcaagta ttaataggaa
    16921 gaaatatcaa tcttatttat ggagatgggt gtgaaaagtg ttttgaaagc acaggatatg
    16981 aaagcaataa tatatgtaag tattgtggtt ctatagttgc atgtaataat gtaaatttag
    17041 aactttatga aggagaagtc cttggaattg taggtgaatc tggttcagga aaaagcactt
    17101 tattaaaaat actgtttttc caagaacatg caaatagtgg agaagtatat atatcccatt
    17161 acaataaaga cacaaatata ctagagcttt cagaccaaaa aaagagatac ataaagaatc
    17221 attttatggg tattgtgtat caaaatcccc accttggttt aaatttagac tttagtagtg
    17281 gtggtaatat agcagaaaaa ttattgatgg caaatttata taatgttgaa aaaataagag
    17341 atagaggcaa agaactttta ataaaaacta atatacctgt agaaagaata gaccataaac
    17401 caaaatactt tagtggggga atgcaacaac gagttcaaat agcaaaagct ctttcaaata
    17461 accctccaat attgctatta gatgaggtta caacaggttt agatgtttct gtgcaagcgg
    17521 aagtattgga tttaataaga gaaatccaaa gagaacttaa gatttctatg atagttgtat
    17581 cccatgactt tgatgttata aagatgcttg ctgataggac aattgtaatg aaaaatggaa
    17641 gtgtaattga gtctggtctt acagaccaaa taatggagga cccacaacac ccatatactc
    17701 agcaacttat aaattcattg ctataaatat cgtttgtaaa taagcaaaat gggggttttt
    17761 aataaaatga aagaaactat acttgaagta aataatttta gtaaagactt tgagttacat
    17821 gcattgaaca agactataac ggcatgtagt aatataagtt ttgaagtttc aaaaggtgag
    17881 tttttaggaa taataggtaa atctggagca ggtaagtcta ccatattaaa aagtatctat
    17941 aaaacatata taccaacaac tggagaaata atttttaatt cagaaatata tggtaatgta
    18001 gacctggcta aaattggaga ccgagaaatg ataaatctta gaaagaaata ggatatgtat
    18061 cacagttttt aaagacactt ccacgaataa ctgcaattga actggtagta cattctttaa
    18121 ttgagagtgg gtttgaaaaa gattgttcgt atgatatggc aaaagatata cttaaccaat
    18181 ttgaaataaa ggaaaattta tgggatgcgt atccaaataa tttttctggt ggagaaaaat
    18241 taagattaaa tttagctcaa gctatggtta aaaagcctag acttttgtta cttgatgaac
    18301 caactgcatc acttgataat caatctaaaa tatatgtaaa agaaaaaatg ttggagctta
    18361 aaagtcaagg aactacaatg ataggaattt ttcatgatat agagtttatg gaaactgtta
    18421 tagataagac ctttactatg acaaaaggga ctataagtga aagtggggta gcctagatga
    18481 taaaactaat tcataatgca aatattgtat tagaagatat gattttagaa aatggtcatt
    18541 taatcataga gggagataca ataaaaaaag tatcaaatga taagattgat tacgcatttg
    18601 actttaatga gatagatgaa ataatagatg caaaaaactt atatgtaata cctggtatta
    18661 tagatattca cagtgatgcc attgaaaagg aaatagagcc gagaccaagt acattattac
    18721 catttaatat ggcattttat gaactagata aaaaactacc tgcaaatgga ataactacag
    18781 tttatcattc tatatcttta ggggatggag taggagttag aagtattgat aactctttaa
    18841 agatgattaa aaatattgat tcatataaaa atatagatag taagagcata aatcataaag
    18901 ttcatttaag atatgaagtg ttgtattatg aaggtttaga aaaggtttta gaactattag
    18961 atgaaaataa aatagactac ttatcaataa tggaccattc tccaggacaa ggtcagtata
    19021 caaatccaac attttataaa gagtatgcta ctaaagtgtg gggagttaca gaaaattatg
    19081 tagatacatg gttagatgat ttagtaaatc tgcatgataa tttagattgg aataaaatag
    19141 ctaatattat aggtatagcc aaaactaaaa atataaatgt tgcatcacat gatgatgata
    19201 cattagaaaa aatggatttc ataaaaaata taggcataaa tgtatctgaa tttcctataa
    19261 ctcttgaagt tgcaaaacat tcaaagaaat tgggtgttct aacttgttta ggtgcaccga
    19321 atattgtaag aggtaaatct cataataaca atttaaaagc aatggatgct atattggaag
    19381 attgttgtga cattgtgtgt tcggattatc ttccatcagc tatgataaag tctatgtgta
    19441 tagttgcaga aagaataaat aatttaaata aagcagtcag tttatttacc tcaaatcctg
    19501 ctaaagcagt tggtatatat gatgaaagag gtagtataaa agaaaataaa aaagcagatt
    19561 tagttttagt agatattgat agtgaatatc caaaggttgt aaatactatt gtaaatggaa
    19621 aaacagttta taaaagggag gtataaagat tgctaacaga gttacattgt catacaagta
    19681 tatcagataa taattttact actgaagaaa taataaaaaa agcagcagaa aagaatataa
    19741 atatcttagc aataacaaat catgacacat tatctggatt ggatgaagct cttgtgcttg
    19801 gagagcatta tggaataaca ataataccag gtatagaaat ttcagcctat gattataaaa
    19861 atagaaaaag agttcatatt cttggatata acatagattt aaacagtcaa gaaataaaaa
    19921 atttgtgcaa tccaatggta tgtgacagac ataaagcatc tgttaagatg gtaaataaaa
    19981 ttatagattt aggatacaaa atatctctgg aagatgtaaa gaaatattca tcaaagactg
    20041 gaatatttaa acaacatata atgaaagctc ttatagataa aggatataca gataatatat
    20101 attcaaatct atataaagaa ttgtttcata gaggaaacgg caaggtatat gtatctttaa
    20161 aatatgtgga ttacagagat gcaataaaag ctataaaaaa ttctggtgga atttgtgtgt
    20221 tagctcaccc gggtcaaatg gataatttta gcgctattga agagatggta aaagtaggat
    20281 tagatggaat agaagtatat catccatctc acaacaaaga actagaaaaa gagtcgcttt
    20341 cttatgctaa gaagtataat ctagtggtca caggaggttc agattaccac ggattttatt
    20401 ctcaacataa ttatgaactt ggaagcaaga gcttaaataa agaagattta tttaagttta
    20461 ggttagcttt aggaggggta ttataaatgt cttttttaca agtaaaaaat gtaggtaaaa
    20521 gttatggaca agttaaggtg ttaaaagaca tatctattga tattgaaaaa ggagagttta
    20581 tttgtttact aggtccaagt ggttgtggaa agagtacact acttagaata attgcagggc
    20641 ttgaggataa acatggtgga aaaataataa taaatgataa ggatatgact aattcaccac
    20701 ctgaaagtag aaattttggt atagtttttc aatcatatgc attatttcca aatatgaatg
    20761 tttacaaaaa catagccttt ggactagaaa ataaaaacat aagtaaatct aatattgata
    20821 aaaaagttaa agaagttcta gaagttgtag aattaagtgg atatgagaaa aaatatccat
    20881 cacaattatc aggtggacaa caacaaaggg ttgcattagc tcgtgcgatt gctttagagc
    20941 cagacttttt acttcttgat gaacctttat ctgcattaga tgcaaaagta agacttaaac
    21001 ttagggagca gattagaagt ttacatagaa aactaggcat tacaactata atggtaacgc
    21061 atgaccaaga agaagctctt tgtttagctg ataagatggt tgttatgaat agaggagaaa
    21121 taatacaagt tggaacgcca aaggaggtat ataaaaatcc agaaacacct tttgtagctg
    21181 attttatagg aacaataaat tttatagatg atggtattaa taagatagct attagaccag
    21241 aagatataaa agtagagtct aatagagatt ctaaagataa ggatataaaa gtgggagaaa
    21301 ttttagatat cgaatttaga ggatttaact atagaattac agttgagtat cgttctaagc
    21361 aaatgaaatt agatgtagtt tccaaagttg cagaacaaat gaaactgtgc ataggttcta
    21421 aaataaactt taagatacct aaagaaggaa ttgtacaata taaatcagag ggatgtgctt
    21481 aatagctagg ggtgaataaa tgataacatc aaaaaataaa agaagaataa gtgatagcac
    21541 aatacaaaaa tatttcttga ttttttcggt aattgtacta atagtattta tattatttcc
    21601 attagtatca ttattaaaaa atgcatttat ggatacaagt ggaaatttta taggaatttc
    21661 aaactttagt aaatatgttg aaaatccaag tcttatagca tcatttaaaa attcaatttt
    21721 tgtatctaca gtctcatctt taatatcact atgtttagca tttatatatt catacgcaat
    21781 aacaagaaca aacataaagt ttaaagaatt ttttaaaact atgggaatgt ttccactttt
    21841 tgcaccaact atgttatatg gtatttcact tatatacctt tttggaaata agggaatctt
    21901 tacaaccatg ggtctggaag taccactata tggtccatta ggaataatta tttctcagat
    21961 tctatttaca tttccacaag cttttttaat attatctgta gcactttcga tggctgatta
    22021 cagactttat gaagcagcag atagcttggg tgctagtgaa tttaagaaat tttgcaaaat
    22081 aacaattcct ggtataaagt actcattact tagttcattc tttgtatcct ttatacttgc
    22141 atttacagat tttggagcag ctaaggtagt tggaggaaac tacaatgtac tggctactga
    22201 catatataaa caagtagttg gacaatttaa cataccaatg ggagctactg tttctatggt
    22261 aatgttaatt cctgtactaa tagcatttac attagataag atggcaagta agaaacaagg
    22321 tatgaccata actgcaaagt ctatgccata taagattaag gaaaataagt ttagagatag
    22381 agtattttta atagtatgta gttttataac attgctaatt tttattttaa tattcgtttc
    22441 agttataggt tcagttataa agttatggcc atataattta agctttacaa tggaacacta
    22501 tacatttaaa ggtattttgg gaagtggaat aaaaacatat ttaagcagtt tgaaaatatc
    22561 aactttaaca gcaatatttg gaactatatt tgtatttttt agtgcttata tgatagaaaa
    22621 ggtggataag tttcctaaat taagacaaac agcttacctt ttatcaatga taccaatggc
    22681 cttacctggc ttagttttag gtatatcata tataactttt tttaactcag caagtaatcc
    22741 attaaatttt ttatatggaa gtacagcaat attagttata gtaaatgtag ttcattttta
    22801 ttcagtttgt tttataacct caaattcatc tttaaaaatg ttggataaag agtatgaatt
    22861 agttgcaaaa tccataaata ttccattcta taaagtattt tttaatataa cagttccaat
    22921 gtctataaca tcaatacttg aaatagtagt atattatttt gtaaattcaa tggttactgt
    22981 ttcagcatta atatttttat atacacctca aactcagact gcatcaatat caatactaaa
    23041 gttagatgag ataggatata taggaccatc agctgctatg gcagtattag tgcttttaac
    23101 aaatataata gtaagacttt tgtacgaatt tgtaacaaag aaattaaaaa ataacacaca
    23161 aaaatggcag caaaaagatg ttgcataggg gaggtaaaaa tgaaatttaa gaagctagtt
    23221 tctttaggag tattatcaac acttttatta agtgtaataa caggatgtag tactgattca
    23281 tcaggttcag attcaaagtc tgatagtaag acaaaagggg atttaacagt ttacacagca
    23341 attgaagaag atagtataga gccatattta gctacattta aagagaaata tccagatatt
    23401 aaattaaata ttgttagggc atcaacagga gatataacag caagattatt agcagaaaag
    23461 gataatcctc aagcagatgt tgtatgggga gttgcagcca caagcttatt ggttgcagat
    23521 gaccagggga tgttagaacc atatgctcca aaaggttctg aagaaataga gtctgcattt
    23581 aaagatgata aagaagttcc ttcttgggtt gggatagatg cttggatgac aggtataaca
    23641 gtaaacacta aagaattaag tgataagaac atcccagttc ctagttctta cgaagattta
    23701 ataaagccag aatataaagg tcttatatct atgcctaatc catcttcttc tggtacaggg
    23761 tacttaacag tatcagccct tatacaaatt atgggggaag aaaaagcatg gcagtatatg
    23821 gataagttac atgagaatat tggtgtatac actcaatctg gttcagctcc agctacatca
    23881 gcagcttcag gagaatatcc tattggtata tcttttggat atagaggtat aaagttaaaa
    23941 gaggaaggct atccagtaga agtagtattt ccaaaagaag gttctggatg ggatatagaa
    24001 gcaaatgctc ttgtgaaaaa agataatata aaagaagcat caaaagtatt tttagattgg
    24061 gctataagta aagatgcaat gaacgaatac tctaaaaact atgcagttac tactatttct
    24121 acaggaaatc caataccaga aggattccct aaaaagccat tagagcaaat gatagataat
    24181 gatttaaaat cagcagcaaa aaatagagaa gatatactaa ataaatggat atcaaaatat
    24241 gatggtaaga cagaaaaaga gagttaagta aaactataca aatggagtaa aaagaaaaat
    24301 tttttttaag tagattttat tattataata taagttgaga ataatatagg tcaagaaaag
    24361 tgaatattct ataaaaatgt atagagtaag tataccattc agtttgaatg gtatattttt
    24421 tatttttaga gattaattta gaaatagata tactacagtt taaaatagta tattttaatt
    24481 tcattattaa agtatagatg ttatatataa agtaaataag atattaaata attataaact
    24541 aaagtaaata aaatattgag cgattattaa aaagatatat atataattta atttgagcag
    24601 tttgttatat attataaaaa aagagaaaaa taaaaggtaa attgtttctg gataacttaa
    24661 aattggaagt aagaatattt aactagagaa gaattattta agtttaggtt agctctagga
    24721 gtagctgatt ttataggaac aatagatttt atggatgatg atataaacat ggtagcaatt
    24781 agaccagaag atataagggt agaatttaat agagatttca aagaaattat agacctcaaa
    24841 ctcagaccgt atcgatataa aaactaaagt tagatgatat agtgttgtag ataggaccat
    24901 cagctgttat ggcagtatta gtgcttttaa caaatataat agtaaaactt ttgtatgaat
    24961 tgataataaa aaaattaaaa accaagacat aaaaatggca acaaaaagaa gttgaataag
    25021 ggaggtaaaa atgaaattta agaagttagt ctctttggga atattatcaa cacttttatt
    25081 gagtgtaata actggatgta gtaatgtttc atcaggttca aacttaaagt ctaataataa
    25141 gacaaaagga gagttaacag tttatacagc aattgaggaa gatagtatag atacatactt
    25201 agctacattt aaagagaaat atccagatat taaattgaat gtacttagat tatcagtagg
    25261 aggtataaca gcaagattat tagcagaaaa agataatcct aaagcagatg tgttatgggg
    25321 tgttgcagct acaagtttga taattttaga tgacaaagaa atgctagagc catacgctcc
    25381 gaaaggcttt gataaggtaa attctgcatt taaagatgat aagaaagttc cttcttgggt
    25441 tggaatagat gcttggatga ctggtataac agtaaatact aaagaattaa aagctaaaaa
    25501 tatatcagct cctagttctt atgaagattt aataaagcca gaatataaag atcttatatc
    25561 tatgcctagt ccagcttctt caggaacagg atatttaaca gtatcagaac tcatacaaat
    25621 tatgggtgaa gaaaaagcat ggcagtatat ggataaattg cataaaaata ttggtgtata
    25681 cactcagtct ggttcagctc cagctatatt agcagcttca ggagaatatc ccattggtat
    25741 atcttttgga aatagaggta taaagttaaa aggtgaaggt tatccagtag aagtagtatt
    25801 tccaaaagaa ggttctggat gggagataga atcaaatgca cttgtgaaaa aagataatat
    25861 aaaagaagca tcaaaagtat ttttagattg ggctataagt aaagatgcaa tgaatgagta
    25921 ttctaagaat tttgcagtta ctacaattga cacgggaaat ccggtgccag aaggatttcc
    25981 aaagaatcca ttagaacaga tgatagataa tgatttaaaa tcagcagcaa gaaatagaga
    26041 ggctatacta aataaatgga tagaaaaata tgatggaaag acagaaaaag agagctaagc
    26101 cttgcaataa aatttagtac aaaaagcgcc tagaatataa gttttatatc taggctcttt
    26161 tgatatattt atttaaaatg catatttcta tataaaaata aatagtttag taccttgatt
    26221 aaattaaata aaaaccttaa aataaagaga tgtaaagaaa aactaaaaac gaataaaagg
    26281 tgaatttata tgataaaaga aataatagta gtagagggta gagatgacgt tacagcagtt
    26341 aagagagcaa tagatgcaga acttataact acaggtggat ttggatttcc aaaaggtgta
    26401 atggagcgta taaaagctgc taatgaaaga cgtggtgtta taatatttac agacccagat
    26461 tttgcaggtg aaaaaataag aaaaaaaata gcatcagaag ttccaggatg taaacatgca
    26521 tttctaccga gagaggaagc taaaaaggat ggagatatag gtattgagaa tgctactcct
    26581 caaagtataa tagcagctct gaataaagtt agaactgaaa atacagaaaa aagagatgaa
    26641 tttaagcaag ttgacttaat tagaaatggt cttataggta atgaagaagc atcacttaga
    26701 agagatgcac ttggaaaaat acttggaatt ggatatggaa atgcaaaaca atttttaaat
    26761 agattgaata attatggagt tgaaagagaa gaatttatag atgcattaaa acaaatctaa
    26821 acgtaatgtt taatgtatga aaaatatgta tataaaataa attgtggaat tacggttaat
    26881 ttaagatgaa ttatttataa tatacacctt attttaaatc aatgtaaata catataaata
    26941 agtataatta ataaaattaa atatcaaaat aagttaaaaa ggagtaaata atggatagac
    27001 tatcttcaca taatgcaaca aaggaagtag tacaaaaata taattttaaa ttttcaaagt
    27061 ctttaggtca aaatttcttg atagatagta atataattga taaaatctta tctggagcta
    27121 gaatcacaag aggagataat atcatagaag taggacctgg tataggaact cttactcgtg
    27181 agatgggtaa aatagcagaa aaagtagtgg ctatagaaat cgatagaaat ttaattccta
    27241 tattgaaaga taccttgtca gatttagata atacagaggt tgtaaatcaa gatatactaa
    27301 aagtagacat acaggaatta gtaaaagata aattaaatgg tgggccagtt aagcttgtag
    27361 caaatcttcc atattatata actactccaa tagttatgaa atttttagag gaagacatac
    27421 ctgtaacaga catagtagtc atggttcaaa aagaagttgc agatagaatg aatgctattc
    27481 cgggtactaa agattatggg gcattatcta tagctgttca atactattgt gatacagaga
    27541 ttgtggcaaa agctccaaga catatgttta taccacaacc aaatgtagat tccacagtta
    27601 taggtctaca tgtaagagat aaaagaaaat atgatgttca taatgaagac atatttttta
    27661 aaacagtaaa agcatccttt ggacaaagaa gaaaaactct tcttaattcg ttgggaggtc
    27721 ttggttttct taataaagat gaaataagag aagtattaaa agaagctaat atagacgaaa
    27781 aaagaagggg tgaaactctt agtatagaag agttttcagt tctttcaaat ataataaata
    27841 caaaagtatc ttctaaatag aaggtacttt ttttaatttt gttaacatat attgtttaga
    27901 gaaactgtgt taagggggga ttgcagtggg ttctaaaaga aagtttaaaa gagactatat
    27961 aatactagaa gctaaagaca taaactttag atacaaagaa cgagtactgc caaaagcttt
    28021 tgcaaaagtt gaagtaaatg atgaaaaagc aattattgca ttatatgtag aaaatctaaa
    28081 atatgttaaa gatgggtata aagcagtagc aataaaagat gaccatggat taatagactt
    28141 aggaaatata attttaaatg aacaaggaag aggtgaattt gttttagatt tagaagatta
    28201 tgatgatgag ataaaaggta ttgcattatt gtatgaaaga aatatacctt taattggatt
    28261 taaaggaaat aagcttgaaa attatgagga catattattt caagaggtag aggaagaaga
    28321 atatgaagaa tatgaagagt tggaagaaga agacgaagag atagaggaga atgaggaaag
    28381 tgatagagac gaagatagtg aagaagaata tattatagaa gaatatgatg aagatgagta
    28441 tgaagactat tgggaagatg atgaagatat tgaagaagga gagttaaaag caagaacgga
    28501 agtagaagat tctgatgatg aggaaataga agagttcaat aattataagg aaatagaaaa
    28561 ttataatagg gttaaagtac aggaagaata tatagacata gaatatgatg aagaagaaga
    28621 ggaagaagaa gtttttgaag taaatagaga agaagatagg tttgtttcct caaaacctac
    28681 taaatcaaag aaagttcaaa aagatcagaa taatattgaa aaaataaaaa gagctaatgg
    28741 agtaagtcaa ggagagagtg gaaataaaca aaccagtaca ttacttatgc caagacaaat
    28801 aaaaaaaggt ttgaaattat ttaaagaagt aaaacctttt gtaacagatt atatagataa
    28861 gacaagatgg tggaaaatag agataaatcc tacaacactg tgtggatata caatgcctta
    28921 tttaggatat ttaaacgtat tgaattacac tatgtatagt gatgcagttt tacattcata
    28981 taaatacaga cactatttat ttggagttca gtatgatgaa tataataaga gaaaacatta
    29041 tatttatgct atcccaggaa atagaaatga acagccagac aatggaagca caggattttt
    29101 aagatatcaa gcttgtgata atagaacaaa tagtttagga tattggctat gttttataga
    29161 ttctagacaa agaaatatag ttaggtaaaa ataataaaaa tgaaaaaatt tagactcaat
    29221 tcttatttta ctgaaaaaat taatgaaatg tagtacaaaa ctttaaaaac tattgataat
    29281 atttaaatat tacactacaa tatatcttga aatacctatt atattatgga ggaaaattat
    29341 gataaacgag caaagaattt taaatgagtt tcttgaatta gtacagatag atagtttatc
    29401 tttaaaagag gggaatgttg ctaaagtatt agttaaaaaa ttagaagaaa taggttgttc
    29461 agtagtaata gacaatgctg gtgaaaaagc aaatggagaa actggtaata taatagctac
    29521 attaaaagga aataaagaag gaaagaaaat attatttagt tcacatatgg atacagtaac
    29581 tccaggtata ggggtaaaac ctatagtgga tgaagcaaat ggaataataa aaagtgatgg
    29641 tactacaata ttaggttctg atgataaagc aggtatagca gctatattag aaggcttaag
    29701 atatataaat gaaaataaca tagaacatac tgatatacaa gttgtattct ctatatgtga
    29761 ggaatgtgga ttagttggag ctaaaaattt agactatgga aaaatagatt ctgaatatgc
    29821 atttatatta gatagtggtg gttctccagg tgaaataata gtaaaagctc ctgcacaaga
    29881 tgtaataaat gttaagatat taggaaagac tgctcatgca ggtcttgaac ctgaagctgg
    29941 aataagtgct ataatggtag ctgccagagc aatagaaaat atgaatttac ttagaataga
    30001 cgaagaaaca actgctaaca taggaattat aaacggtgga acagctacaa atatagtaac
    30061 aggagaagtt aatatagttg cagaagccag aagtctaaaa gaaaataaat tagatgttca
    30121 aactaaacac atggtagaga cttttgaaaa agctgcgaaa gattttggag ctcaaattga
    30181 gatagatgtt aatagagcat acacaccaat agatgttagt gaggattctg aaataataaa
    30241 acttgcaaag aaggcttttt caaacttagg tatagaaggt catactgaat ctacaggagg
    30301 aggtagtgat acaaatatat taagtaagaa tggtatcgaa gctataactt taggaattgg
    30361 tatgaaaaat gctcatacac taagtgaaca tatagctata aaagacttat atgattctgc
    30421 taaaatggta gtggagataa taaaggaagc ataaatttaa ataatagtgt ataatatata
    30481 tatcgcctag cttaagctag gtgatttttc attttataga agattgataa tctctattga
    30541 aagcaaagag tatacatttg catataagag agtgtttaat ttatgttcaa atgtaggttc
    30601 ttaataatat ttagattgtt tcataaggga ggaataaata tggaaacaag gtatgaagaa
    30661 gcaaataaaa taacaataca atcaatactt tggaatatag tattaacaat aattaaggtt
    30721 atagctggtg ttattggtaa ttctagcgct atgattgcgg atggattaca ttcagcatca
    30781 gatattataa gttctatagg agtactaata ggcaattatg tatcttctag acctggagat
    30841 agagagcata attatggtca tgagaaagca gagacattag tatcatttgt gttatcaata
    30901 ttgcttattt tcgtttctat aacaataggt atagaggcaa ttaaatcttt atttaactta
    30961 gatgcattaa gtgttccatc aatattacca ttagtagtat cagttatttc aatcctgata
    31021 aaagagtatc aatatagaat aacaataaaa gttgctaaaa agataaattc accagcccta
    31081 aaagctgatg cttggcatca caggtcagat gctttatctt cagtagctgc ttttataggt
    31141 ataggtggtt ctattttagg gtttaaacca ttagacccaa ttgcgtcagt tgtagtggct
    31201 atatttgtag ctaaagtagg aattagtata cttataagtt ctgttaatga attgatggat
    31261 gtttcagttg atgaagaaga gataaaagaa ttaaaattta ttgtagcaga tacagaaggt
    31321 gttaaaaatc ttggtgatat aaagactaga aaacatggag ctatggcata tgtagatttg
    31381 actatatgtg tggatgaaaa tttgacagtt aagcaaggtc atgatattgc taccaagctt
    31441 gaaaaacata taataaaaca tatggaattt gtaaaaggta taacagttca cgttgaacca
    31501 tgtactaatt gccaaggaaa taagtgtaat aattaattaa aacttaaaaa aaagtgtaaa
    31561 aagttatata attgttttat gattataaac tctaggggtg gttaaatgag caagaaaaga
    31621 aaactaaaga aaaaagctgc aatattaata ggagtagttg ttttctttat aatatacttt
    31681 atatccttta gaataggaat aaatatggaa aaggataaaa gtgaagtgcc aaagaaggta
    31741 gaaaaagaag aagaagataa taggtcttta aggactcaaa taaaagagaa gaagaaggtt
    31801 tatatatcag ataaaaatat agaaaacata aaaattgaag aagatatgtg ggatgaaata
    31861 aagttatttt tctcagattt taagaaagta agaaatacta cttcttctta cgaagcagtt
    31921 tatgaaggtt attctgatga tggagttaaa ttttctactg accttaactt ttttagagta
    31981 tatactgtaa ataaagaaga atattataaa gtaccagtta gttctaagga tgcttttaag
    32041 aaacttttag atgagagtat atatacttcg tttgaccttt taagtcatta taaagattgg
    32101 aaagaggtta ctataactca tggaaaagaa attaaaaaag ttcatagatg gaaatttgat
    32161 gatttagcac ataagatgat ttcaaagagg gttgtaggaa aagttcaacc tgagaaaagt
    32221 aaggaaagaa gtgactataa ttttactata aatataaaag gtgataattt tgatgtaaaa
    32281 gttgatacaa tgggaaaaga ttatgtaaaa gttacttcta agaaaaatgt atcttactat
    32341 gaggttcata caagtttatt tgattacctt aaaaatgaga tatttgaaat tggaaagaaa
    32401 taagacttta agaaggctat caaattagat atttgatagc ctaaattatt ttatatatta
    32461 tttttcaacc aacaagtctg caaccttata aattggacca gcaccagcag ttattactaa
    32521 atcattatcc ttaacatttt cacgtaagta ttttactata tcttcaaatt cttttatata
    32581 gatggcatct acattgtttt gatataattt ctcaaccaag tccttagaat gtatatctcc
    32641 tgggtctttt tccctagcag catatatatc tgttatgata actttatcag cagcatagaa
    32701 tgcctctgaa aattcaccta aaagagattt tgttctagta taagtatgtg gctggaagat
    32761 acaccataaa gttgattttt ttaatttttt ggcagcagct aaagttgctt ttaactcagt
    32821 tggatgatgt gcataatcat ctactactaa agcattctta tagtaccctt tagtttcaaa
    32881 tcttcttccg acacctttat aaatttttat attttttctt atagtctcta agtcaatacc
    32941 agaaacaaga gctgccatta tggcagaaga agcattgtat atgttatgaa gaccatatac
    33001 agaaagttca aattctccta aatctcttcc ttcatattct attctaaata ttccatgacc
    33061 actattgtca aagtgaatat cttttattac agcatcattg tcagaatctc tgccgtattt
    33121 tataatagta gctttaacat catacaatat gtcatcaata ttttcatcat cgccatttat
    33181 tatgaaatag ccttctgggg gtaataattt tccaaatttg ttaaaagaag ccttgatttc
    33241 atctattcca gagaaataat caagatggtc ttcttcaaca tttaaaacta tagatatctt
    33301 tgggttaaaa ttaaggaaac tatctacata ttcacatgct tcagttataa agtggttgga
    33361 attacctatc ttaacattac cacctatcat acttaagtta ccaccaacta gtatagttgg
    33421 gtctaagtct gcatattcaa agattgtaga taacatagat gttgtagaag tttttccatg
    33481 tgttccagaa actgctatag aatttttata ttccctcatg atttggccta aaaaagttgc
    33541 tctgttcatt accaatttat ttttttcttt agcagccaca agttcttcat tgtctggatg
    33601 aactgctgct gtataaacaa ccatatttac atcatctgat atattatctt ttttctgacc
    33661 aatataaata gttgcccctt ggtccctaag tttgtctaat aggtatgatt cgtttgaatc
    33721 cgaacctgaa acttgataac ctttattgat acatatttca gctaatgcac tcatgctgat
    33781 accgccaatt cctataaagt gtatattcat aataaaacca cctttctttt taattaagtc
    33841 ctacaatatg aactatttct gtggtataat aatataatgt tcaatatttt ataattaata
    33901 tgcatataat attatatgta ttttattttt gaatataata aaacataagt aatattatac
    33961 cacaataaga attgttatgc attagttagt ttaacgttat ataaaggtac ttgtaggagg
    34021 aaataataat gaaatttaaa agaacagaga gaattggagc aatagttaaa atactgtctg
    34081 ataatccaaa taaaatatat actttaagtt attttacaaa tcaatttaat gcagcaaaat
    34141 caacaataag tgaagattta ttagttgtaa aaaatgtatt tgagaagcta catttaggta
    34201 aagttataac tatttcagga gcagcaggag gagtaaaata tatacctaaa acttctatag
    34261 cagaaaatgc agagttctta atggaattat gcgagagaat atgtgacaag tctagaatac
    34321 tatctggtgg ttttttatac ttgattgacc taatttacga ccctacaata gctgctaaga
    34381 taggaaagat attcgcatca aatattgagt atgtagatgc agattatgtt gtgacaatgg
    34441 aaacaaaagg tatacctatg gcacttatga ctgcaaaagc tatgaattta cctctagtta
    34501 taataagaaa agatataaag gtatcagaag gtcctacact tagcatgaca tatgtgagtg
    34561 gaaacagttc taaagttgaa agtatgagtt tgccaagaaa agctcttaaa ccagatagta
    34621 aagttataat tatagatgat ttcatgaggg gtggaggtac tataaaagga atggtagacc
    34681 ttatgaatga atttggtgca gaggttatag gtactggagt attcatatct acaacgaatc
    34741 cttcagaaaa aatggtaaaa gattatattt cattgattca attggatgtt aatggagata
    34801 aaatagtagt agaaccaaac ttaaagactt ttaaagatga atatagaaat gaagatttag
    34861 acgaagaaga agattcagaa tttgaatttg agatagatga agattaataa aaaaaatatt
    34921 tagaaaaata tgtaaaaata aaaagaggat atccctagtt gttcatagaa ttatttaaaa
    34981 aacagtttat attaatttat tccagcgata ataattttaa tataaattaa tttctgtcaa
    35041 aatcaaaggg ggatattttg gtatgaagat aactgacgta agagtaagaa aattaacaga
    35101 agaaggtaag atgaaatgta tagtttcaat aactttcgat aatttgtttg tagtgcatga
    35161 tataaaagtt atagaaggcc ataatgggct atttatagca atgcctagca gaaaagtagg
    35221 cgaaggaaat ttcagagata tagctcatcc aataaatgca gaaatgagac aagttttaga
    35281 agatgcagtt ttacaagcgt atcatgaagc attagttcaa tgggaagtag ctgctgaata
    35341 ataataaata tataaaatgg agagagcccg aacatttagg ctctttttaa atgtagaatt
    35401 tctattaaaa tatgtacttt ttagtaaaaa agtgctatat tattagtgat aatgtatatg
    35461 ttgtatacaa attgttagat aaatgtatta taatgtatat tgattaagag aataatacga
    35521 ataaaattaa attagattga atggagtgta tcaatgaact ttaaagctat aatccttgct
    35581 gctggcaaag gaacaagaat gaagtctaaa tacccaaaag ttatacataa agtatgtgga
    35641 aaagaaatgg ttaaccatat tatagatgtt tcaaaaaaat caggggtaaa agatactgtc
    35701 gtgattttag gacatgaagc tgatgtagtt aaagaaaagc ttgcagaaga aattataata
    35761 gccatgcaaa cagaacaact tgggacagga catgctgtaa agatggctaa agaatatatt
    35821 aatgatgaag atacaatagt tgtactttgt ggagatactc cacttataaa agaagagaca
    35881 ctaaagagac tatttgaata tcatatagaa aataaatatc atgctacagt tcttacaaca
    35941 agagttggaa atccaacagg ttatggtaga ataataagag ataagaaggg tgaccttctt
    36001 aaaatagtgg aacaaaaaga tgcaaattca gaagaaaaga tgataagtga gataaactct
    36061 ggaatttatt gttttaatgg aaagagtctt agagaagcac tagatttgct aaataataac
    36121 aattcacaag gtgaatatta tttaactgat actgctaaaa taatgagaga taaaggatta
    36181 aaagttggtg catttgcagg ttcaactatt gaagaactta tgggcgttaa ttcaagagta
    36241 gaattatcaa aggcagaaga aattatgaga cgaagaataa atgaatctca tatggtaaat
    36301 ggagtaacta taatagacac taactctacc tatatagaat ctgatgttat gataggcaat
    36361 gatactataa tatatccagg tgttatgtta caaggaaaaa caaggatagg ttcagattgt
    36421 ataattggaa tgaattcatc tataacaaat tcagaaatag gtgatggtac agaaataaaa
    36481 aattcaacta taattgatag taaggttgga gaaaattcta ctgttgggcc atatgcatac
    36541 ttaagaccaa agagtgactt aggaaataat gtaaaaatag gcgattttgt agaagtaaaa
    36601 aatgctatta tagaagatgg ctcaaaagca tctcaccttt cttatatagg agatgcacat
    36661 gtcggtaaaa atgtaaatat tggatgtgga gtagtatttg taaactatga tggtaaaaat
    36721 aaatttaaat caatagtaaa agacaatgcg tttataggtt caaattctaa tttagttgca
    36781 ccagtagttg tagaagaaaa aggatatata gcaacaggtt caacaataac acatgatgtc
    36841 ccagatggtg ctttggcaat agcaagagaa agacaagtta tcaaagaagg atgggtagaa
    36901 aaaaagaatc aaaaagacga ccaaagtaag taattatgta gtttattatt ttggctaaaa
    36961 aatttagctc gaaattatta taaattatat tcattagtat tttaaaattt tcaggagggt
    37021 tacataaatg aatactagcg gaagcgagat taaaattatt gcaggtaatt catcgaaaga
    37081 gttagcacaa aaaatagctg actatatagg tgtatcagta ctagattgtg aagtaggtac
    37141 atttagtgat ggtgaaatat gtgtaaacat gaatgagaca gtaagaggtt gtgatgtgtt
    37201 tgtagtgcaa tctactaaca gcccagtaaa tgataactta atggagttat taatcttaat
    37261 tgatgcgtta aagagagcat cagcaggtag aataacagca gttattcctt actatggata
    37321 tgcaagacaa gacagaaagg ctaaggcaag agatccaatc actgctaaat tagttgcaaa
    37381 tttaataact gctgctggag cagatagagt attaacaatg gatttacatg cagctcaaat
    37441 acaaggatat tttgatatac cattagacca cttactaggt ggaacaatat tagcaaatta
    37501 ttttaatgaa aagaaaatag aagatttagt agtagtatct cctgacttag gaagtgttac
    37561 tagatcaaga aaatttgcta atactttaaa tggagaagtt ccaatagcta taatagataa
    37621 aagaagaccg aaagctaatg tatgtgaagt tatgaactta ataggtgatg ttaaaggtaa
    37681 aaatgttata ctattagacg atatgataga tacagcagga acaatagtta atgctgcaaa
    37741 tgcacttaaa gagtttggag caaaagatgt ttatgcttgt tgtactcatg gtgtgttatc
    37801 aggtccagct attgaaagaa ttgctaattc agaaataagt gagttaatag ttcttgatac
    37861 tatacaactt cctgaagaga aaagaataga taagataaag ataaaaacag tagctccttt
    37921 atttggagat gctataagaa tgatattctc taatgaatca gtaagtaaat tattctaatt
    37981 tattgtattt atgagagttg tttaaaagga tataaacctt ttgagcaact cttttttgat
    38041 tttatactta tggaatgtta tttttttctt gttagaaagg tatatattat tgtaaaaaga
    38101 gattatagtt taaaattatg tatatttaag taaaataaac ctaataaagg gtatattatt
    38161 caaaatatta tgaatataaa aaatattaca aaaaagtatt gaaaaaattc agattatgta
    38221 gtattatgta aatataaata aagaaagagg tgtttccaat gggaaggtta gaagatgaac
    38281 ccctaataat taaatgattc agtcacaatc taaagtgaat ataaaaatct attgaaagtt
    38341 tatttataag aattgaaaat agtatctatt ctatctttag tgtttgtgag agggttctgg
    38401 attatataag attactgtaa agagtaattt tgcacaataa gcatatctgt aaatgaagag
    38461 tttcgtttat ataatgattg tggctgaatc ataactataa tagatagaat gtttataata
    38521 gatgatttta taaaatacta tattgtaata gcttttagct ttcaaataaa tattagcaaa
    38581 ggatggaaat gacaatgata aaactaaatg ataatttata aatatctcct tacgatatat
    38641 aataattgta gggagatgtt tctttttttg tatagcataa tttttctaga aattctgttt
    38701 caatatgtaa aaagttggta tatataaata gtataaacag tgttgctaaa atatggtaga
    38761 tattatataa tataagtgga tatgtatata cattatgagt tatataattt gaatttaata
    38821 aaatagaaac gttgatttat gttctgtaat gtgggcacct tggagcatat tgagttagtg
    38881 gtgcaaccgg ctatgaaatt gtatttattt ataaatacta ttattttcat agcttttttt
    38941 atttaaaaaa tggttatatg ttagaaataa atttggttag tacgtttaaa taattttact
    39001 tagattttta accagatata ttgtaagtaa gtattaatta aaaaatttaa gggggaataa
    39061 aaatgaagtt aaaaaagaat aaaaaaggtt tcactttagt ggaattattg gtagtaattg
    39121 caattatagg tatattagca gtagtggcag ttccagcttt atttagtaat ataaacaagg
    39181 ctaaggtagc aagtgttgag tctgattata gttcagttaa gagtgcagca ttatcttatt
    39241 attcagatac taataagata ccagttacac cagatggtca aactggttta agtgttttag
    39301 agacttatat ggagtctctg cctgataaag ctgatatagg tggaaaatat aaattgatta
    39361 aagttggtaa taaattggta ttacagatag gtacaaatac tgaaggagtt acattaacag
    39421 aggcacaatc agcaaagtta ttgagtgata taggtgaaaa taaaatatat acaagcacta
    39481 caacaaatag tttgggaaat ccattaacaa gtaatacaaa aatagataat aacgttctat
    39541 atatagtact tatagataat actgtgatgg acacaacaaa atagttaaaa caatattttt
    39601 ataaaaatat tgtaaattta atgaaaaata taatataaaa gacaggaaga aaatcttcct
    39661 gtttttttat actattttct ttaatgttca attatgaatg atgatataat tgagatagta
    39721 aaggagtgaa acctgtggct aaaaaagtta gaataggaga caaactggtc gaaaaaggat
    39781 atataacaga agaacagctt aaatgggcac tatcagaaca aaaaaacagt ggaaaaagac
    39841 taggagaatt tctagtacaa gaagggctta tagatagtaa cctactaata agtgtattaa
    39901 aagaactctt ggatatagaa agtatatttt tagaagggac agaaatagac actttagcta
    39961 caaagatggt tccagaaaat atatgcaaaa gatatactgt atttccattc aaaatagatg
    40021 gaaataaaat atgtctagcc atgtcagacc cacaagacag agaagcagtt caagatgtaa
    40081 ggcgtatgtc aggtaaagac gtagagatat ttatatcaag tacagaagat ataaacaaag
    40141 caataggtca tgcttatgca cattcagaaa taaataaggc aatgactgag tacaacaaaa
    40201 atagaactgg tggagtaaga gaaacagtaa tacttgaaga agatgtaaat gctgctccaa
    40261 tagtacgatt agtaaataac atactagaaa atgctgttag aatggaagca agtgatatac
    40321 atatagaaca aagtgaaaat tacatgcgtg ttaggtttag gatagatgga atgttaagag
    40381 aatatatgag gatgaactca gcaccatata aggcagtaat cagccgtatc aagataatgt
    40441 cagatataaa tatatctgaa aagagaatac cacaggatgg tagaatctat ttaaaagtgg
    40501 ataataaacc catagatttt agggtttcta caatgccaac taacagggat gaaaagatag
    40561 ctatgagggt tcttgataag agtaatttta tggttagtaa agaagtacta ggaatagacg
    40621 aacatggctc taagatatat gatgaattga taaacactcc ttatggtctt atattggttg
    40681 ttggccctac tggaagtggg aaaaccacta cattgtattc aatgttaaat caactaaata
    40741 cagaaaatag aaatctatta acaatagaag accctataga gtatgaatta cctggtgtaa
    40801 atcaatctca aataaatgaa aaggcagggc ttactttcgc cagcggactt agagctttta
    40861 tgcgtcaaga cccagatata ataatggttg gagagataag agatactgag acagcagaaa
    40921 tagcaattag agcttctctt acaggacatt tagttttaag tacattacat gcaaatacag
    40981 cagttggagc aatttcacgt cttttagata tggatgtgga aagtttttta ataacttcat
    41041 ctgttttagg tgtaatatct caaagactta cacgaaaaat atgtgagcat tgtaaggttt
    41101 catatgaagc agatattgga gaaaaaaagg ctcttggtat tgatgtaaat gaatcagtaa
    41161 ctatttatag aggaaaaggt tgtgaaaggt gtaataatac tggatataaa ggacgtctag
    41221 gtatatttga aatgcttgaa attactccag aaataaaaga gttaatagat tcatctgcaa
    41281 atcaaagaga aattttaaag atggctagaa aacaaggtat ggttagctta aaagaggata
    41341 tagttaaaaa ggttttaaat ggaaagacaa cagtagaaga aatgattaga ataattttga
    41401 tgactgatta aaggatgata ttatgaaaag ttttaaatac acagtaataa aagaggacgg
    41461 aaaaaagcaa actgatgtta ttgaagccaa cgattttaat gaagctagaa atcttcttag
    41521 aaagagaaat cttagagtta ttgaaatcaa agaaagcaaa aataaaaata taagattatc
    41581 tagtataaag agaaaaaaag acttaggagc tgaccagata agccactttt gtagacaatt
    41641 tgctattata gtatcttctg gtataaatag tatttctgga ttagaaacat tagctagaag
    41701 gtcaactaac attacattaa gagaagaaat taatcgtata gtagcagaaa taaaagtagg
    41761 ttctactatt gcagattcaa tgctttcatc aaaatcaaag tttccaaagt tacttggtgc
    41821 tatggtagct acaggtgaag ctacaggtaa attagatgaa gtattaaaaa gtatggcttc
    41881 attttatgca agtgaacaca gggttaaaca aaagcttaga aatgctgcaa catatccatt
    41941 aatagttttg atttcttcat ttataatgat ttttatattt acaacattta tggtgcctaa
    42001 gatgattaat tcaattacaa cagtaggagc aactcttcca cttataacaa gaattgttat
    42061 ggggtttggt atgtttatga agaagttttg gataatagta cttttagtta ttatattatt
    42121 tatctatcag tttaaaaaat atctaaaaac gtcagttgga agggctcata aagatagagt
    42181 tataaataag atacctgttt taggaaaagg aataaattgt atggtagcta cacgattttc
    42241 aagagcattg tatctatttg tatcaacagg atacccatta gttcaagggc ttgattatat
    42301 tatagatagt gtaaataaca ctatggcaga gaagatttta gcatcagcta aagatggaat
    42361 aacaagagga gaaggcttag cagaaaattt agagagatat acgtattttg actctgtgtt
    42421 ggtacagatg atagctatag gggagcagac aggggaatta gagaatataa gtagacagat
    42481 ggcagaattt tatgagtatg aatccgagat ttatttaaat aggatggcct caatgataga
    42541 gcctgtttta ataattgcag ttggtattat agttgcgata ctggttgtat caatattcat
    42601 gccaatgctt agtatatatg atgccatgta ggagggaaag gacaaatgaa caaggtttat
    42661 gtatcatatt atggcgattc tatttccata gttgagggca gatataaaca cgataaggat
    42721 aagttttatg taaaaaattt taatgtgttt tcaatagagg atattgcaca agatttttct
    42781 aaggaaaagt atgctctatt gagatacgca ttagaaaatg ttaagttaaa atcaagacat
    42841 gtagtttttt gtttaaatac aagagatgta attttaaaac cccaaaaact tcctaatatg
    42901 gacaaaaagg atttagacgg atttatgaag ctagagatgg acgaaatgat ggctttggag
    42961 tcagatgaat atgtattttc gtatgaagta tctagtgaaa cacctgataa ttcagatggc
    43021 gatgaatcaa gcttaaatct tattattgga gctatacaaa aggaagaggt aaatgcaatt
    43081 gtagagataa tgcatgaatt tgatttagta ttagatagaa tagatacatt atcaacagct
    43141 tacttaagaa tgcttaaaaa tttagactac aatgatataa tggtaaccaa tataagtgac
    43201 aatagcacaa ttataaatat atataagaaa gatactttat ttattagtga taatatacct
    43261 ataaagataa ctgctaaaga tatggacatg caattattaa atgtagtaga agaatcaaaa
    43321 ggtcttatga attactattc gtcaagaaac tttggtaagg ttacggatac tatattaata
    43381 ttaggaaaaa gatattccaa taaattaatt tatgaaactt ttagctctgc attttcaagc
    43441 tatgtttctc aaggccttac tgagataatg gatatatctg atatgataac tggagatata
    43501 gatgaagatg atataaattc aattgtagag cttttaggaa gtatgataga acctaaaggg
    43561 aaaagagatt ttgaaaatat aaacttttta ccaatggata tacttagaaa acagataaaa
    43621 gctaaacaaa tgaaaaacat actgaaaatt gctccaatag ttattttgat tcttgctata
    43681 ccttatttat gtttaatttt ttcaaataat ttagcaaata aggaacttga aaatgttaat
    43741 ggtgaaataa gaaatattga atctgcatat tatcagattg gaaatataga aaaaatgata
    43801 cagagtaaaa gcgaagaaat aaaggtatat gatatgttaa ttgggaaaaa ggtaaagtgg
    43861 gaaaatttat tggatgatat agataaaaat actccaagta aagttgaact aacaagttta
    43921 tcaacaactt atcaaaatct tggaactaat aataaagctg ataattcaaa aagtaataag
    43981 actacaacag ataaatcaag taacaatgaa acaaaatcaa gtacgaaaag tgatagtaat
    44041 ggagataaaa cagataatga tttaaatgaa gataagacta caaatgtgtc agaagcatta
    44101 actggaaata gtgagactaa tagtaataac acggataaag atgataaaac tccattgtat
    44161 gataagatac caaatgttat aaatatagaa ggaaatgcta aagattcctc ttatgtaggt
    44221 caatttttat ataaattaaa gggattatac tatttcaagg atgttaaatt acatagcata
    44281 aaaagtaatg cagaagattc taactataca tttagtatga cattatacct gaaagaaggt
    44341 gtattaacta atgaataaag atatatttaa aaaagatata aaagatatat ttaaaatgga
    44401 agttagtcta aaagggattc ttataaaggt tataatttta ttagctattt tatcatatgg
    44461 ttattttgga ctttaccctc aatatcagaa atatattgct acaaaaaatt ctgtaaaaca
    44521 ggctactgaa aaattaaata tatataaaga gaaaactgca cttatgccaa aatatgaaaa
    44581 acaacttgaa gaagttgaaa gtgaattaaa agaaaaaagc aaaaatcttt tatatgatat
    44641 gcaagatggt ctttttttaa taggtttaga taaaaaaatg aaggcttata atattgactt
    44701 aaccagttat gacgttggaa atgttaaaga atacgaacat ttttatggta tatcaacaac
    44761 aataagtgtt agaggtgatt atagaaatgt caaaaaatta atggcttatt tagaagaaca
    44821 aaaaaatgtt actcaaatac tagattatac aatgacttca tatatagaac cagaaaaaga
    44881 agaggaagaa acaacaaaca ataaggattt aattaaaaat gtgaacataa ataaagatac
    44941 aaaaatatat tgggtggaag gcgaaaataa gtggcattta tataaggatt gtccattgat
    45001 aaaagaggga gagattataa aaaatgacaa acttttagat aggtctacta attatctatg
    45061 taatacttgt gtacttagag ctgcaacaga aaaagaagca aaaaaagaag tcgtagctcc
    45121 aaaggcagaa ggtgtagtag atgctacatt taaatttata atgtacacta aagagaatac
    45181 tacaatgata cttgatacag ataatccatc ttcatggaga ccaggaaaat ataatccatt
    45241 taagtctagt gcgaaataaa gctaagtaag ctttaaagat aggtgatgag tttgtacaaa
    45301 aataatgaaa aaggtcttac tttattagaa gtaataatag ctgtttttat actgacaata
    45361 gttttaagta tttcttataa agtgttcaat ggtataacat cagcagtaaa aaagcaacag
    45421 attattacag atgctcaagt aaatattaat ctaattaata agtatctaaa tagagatttg
    45481 gaaaactgta aagagctaac taaaactggt tcaggtaata attatgaata caatatagag
    45541 atgccagata atgttgtaaa atatgaagtt tctatagaaa ctaaaaaaaa tacagaggta
    45601 tattctgtaa cgagaatcca aaacaataca attgatacag aaaatgaagt tagagaagag
    45661 ataatctata atcaaccact agttcaaaac aataaagaaa tgaaggaaac accatttaaa
    45721 atagaaaagc aaactggtaa atctatttat actgtaagta tatactataa tgaatcagtg
    45781 caagaaagtc ataaaaatag caatttaaat aacaaaactt atacatttga tgttatgtca
    45841 agaataggat aataagaatt tattaaaaaa taagtaggtt gataaaatat gagtaaaaag
    45901 aatagtgaaa gaggattttc cttaattgaa gtgttagtag ctatggctat tatgggaatt
    45961 gtactatttg cattttttaa tattatcaat actaataaca aagcaaacac taaaaatgac
    46021 acagatataa cttccttaaa ctatgtccaa agtgaaatag aaaatctaag agaaaagata
    46081 aaaagtggag aatttgattt tgatagttta gataaactag aagatggaac tgtcgtatat
    46141 gaaaaattaa tagataaatc aaaaaaagtt gtatatgata aagttcttag tgaaggtgac
    46201 gtgagcttat atgatactcc atatgaaaag attacaacaa taaaagatga agatggtaat
    46261 ttaatcgaca aaggaaatat tacaaataag ataaagacta ttgtagaaga taaaagtggt
    46321 cagatatata aaatagctgt aactgggaaa agcatgaatg actattcaag taaaaaagag
    46381 gttaaaattg taactgaaat atttaaagat aaataatttt acttgggggt gagattttga
    46441 ggaagtggaa taaatttaaa agtgaaagag gggcagcttt agttttagtt ttggttgtag
    46501 tagcattgct ttctattgtt ggattgatat tttcaaatca gatagctaat agaataaaat
    46561 ctacaaagac tactaatgaa ggtatacaag caaagtattt agcagagaca tgtgtggaaa
    46621 atagtattga taaagcatat gaaaaattgt atgatgagct tgagaaaatg gataatgagt
    46681 ttaaaagtga aaatcaagaa aaatccatat ctaggtcaaa attaagaaat atatcagatg
    46741 aagattttaa taatcaagat gaggaaaata ttgaagcaga aagacttgga tatatgaata
    46801 atataaattt ctatttaaat aaagcttctt cagacttgga aaaagctagt atggaattga
    46861 aaaagctata tgatttagat atgttggact atagagacat tgaatatgta gatgcaaata
    46921 ttatttcaca tagagattct atcttagaaa tttgcaagaa ttatacttct ggagatatta
    46981 gtaaaataaa tgaatatatt ctgaaagaag atatagactc aactacattg attgaggcaa
    47041 agttagtgaa taatgatatt cttttaaaaa agtttttaga agaaaataaa attgaaaatg
    47101 aacatttaaa ttcagccttt tcacatactt ataaggcatt agataacatt tctttggcga
    47161 tgcaaaatat gattgagtat agacatacgt ttcatataga tgagccaaaa gtagaagtat
    47221 ctaatgggat tccagactct caacaatatt atgaactaat acaaaatcct ataataaata
    47281 gtatggagta tagctggaat agtaaatggg atacattaga aaacctattg gaaattttac
    47341 caaatcaaac tcaaggattt aattctttaa gagttcattt gagaaataat gtaagaaaat
    47401 ttgagaagtt aagcgataat atatctagtg gtaaaaaaaa tacagcaaaa aatttcttaa
    47461 agtataaaga gttattgtat gaaatatcag accaatgtaa tcaactaaaa agtatgtctt
    47521 atgagaaaat acctgttaaa tatgataaca tggctttgat aacaactttt gactatatac
    47581 aaaatgagct tttagcagag ataaaatgca gattaaaaga attaaaacca caagaaattg
    47641 ataaaacaga aggtattact ataaaaatac ctttttataa ggctgactac gacatgacaa
    47701 aagaaggatg gcctaaatta aaagaaaatg gttcaggggc ggagttaagc ttaatggtaa
    47761 ctggtgataa aaatggaata aaagaagtgg aagttacaga tggtaaaaaa aatattattg
    47821 gtttaggtgt tgaagaaaat tcaaattcaa agtataaggt tgacgccatt gtaaacttta
    47881 atctaaatat agatacaaat gtagttggaa attatgatat aaaagataaa attttgatta
    47941 atcatgatat aagttcatac aaaaaagtaa actaaatata agaagcaact tagtataaat
    48001 aacaaaataa ttttattatt tactactaaa aaaataagta aactaataga agatatggag
    48061 agtaaatatt atgtatattt atgatttatt agagcaaggt ataagactaa acgcatcaga
    48121 tatacacata acagttggaa caaatcctgt agctagagta aaaggtggat ttgtaaaact
    48181 aagtgaacaa atattgacat cagaagtaac aatgcaaatg gcaaaagaca tagcagggga
    48241 atctatgttt aaagtaatag aagaacatgg agaagctgat ttttcagctt ctctaaaaac
    48301 aggagaaaga tttagggtaa atgcatatag gcaaaaagga aattacgcaa tagcaataag
    48361 gactataaca gcagaaattc caacatttga aaaattaggc cttccagaga gtataaaatc
    48421 ttttactgaa aagcataaag gattagtttt agttacaggt ccaacaggaa gtggtaaaag
    48481 tacaacactt gcaagtatga taaatataat aaatgaaaaa caacaaaaac atataattac
    48541 acttgaagac ccgatagaat atgtacatca tcataaacaa agtttagtaa atcaaagaga
    48601 agtaggaact gatacagaaa gttttcattc agcccttaga gctattttgc gtcaggaccc
    48661 agatgtaata ctaataggag agatgagaga ccctgaaact gtttcaatag cattaacagc
    48721 agcagaaaca ggtcatttag tattttcaac actacataca gtaggggcag ctaagacaat
    48781 tgatagaata gtagacatgt ttcaaccatc ccaacagcaa caaataaaaa cacagttatc
    48841 tacagtttgt gaaggtgtgg tatcacagca gttacttcct acagcagatg ggaaaggcag
    48901 aatagcagca attgaattga tgtttgctac tccagcaata aaaaacctga taagagaagg
    48961 caaaacatat caaattccaa acatgataca aactggagtt aaagtaggta tgaaaactat
    49021 ggaccaagat ttaatggaac tttataaaaa tggaaagatt acaaaagata tggcacttag
    49081 taggtgtact gaccaagagt ttatgacaag aatgataggt ggagtaaact acaatggata
    49141 ttataatcgt taatctatat gtatttatag tgggtatagt gtttggaagt ttctttaacg
    49201 tctgtatttt taggattcca gaaggtatat ctatttctag accaccttct cattgtatga
    49261 gttgtaatac tagactaaag ccaatagact taataccagt gctaagctat ttaatgagtg
    49321 gcagaaagtg tagatattgt tatgagaaaa tttctagtag atatgctata gtggaattaa
    49381 ttacaggact tttattttta acagtattta tgttatatgg aatatctaca tcaactattt
    49441 attatttggt tcttgtgtct ttactgatta taattacatt tatagatatt gaccacttta
    49501 taataccaga taaaatattg gtttttggag ctatattttc tatgattttt aaccttttat
    49561 ttaaagaaat tccagttaag gattcaattc taggtgtttt tatttgtgga ggaagtgtct
    49621 ggattatagt tcttttgatt gaatttgtaa taaaaaaaga gtgtatgggt ggaggagata
    49681 ttaaactatt tgcaatgcta ggcctttaca tgggtgttaa aaatggtctt ttgacagcct
    49741 tactaagcgt ttatgtagga gcagtctatg gaatctgtgt aataattata agtagaataa
    49801 aaggaaagga atataattct gttataccat atggaccttt tatatctatt ggagcattaa
    49861 taacaatctt atgtggaaag aaattacttg aactttattt ttctatggtt atatagatga
    49921 tagtcaagtt aaataaagtt ttaatttaaa aaaatgaatt aaagtattta ataaggacaa
    49981 tattattatt aaccctatta ctaaagtgct acaaactatg gagtatataa taataatttc
    50041 cttatttttt gcacatttga taaataaatc tctatgtgtt ttttgtgata gagaaaagaa
    50101 aaatttatac aatacgtttt ttatttacat aataactgta gttttatctg tattaatata
    50161 tctaaaattt gggattagtg tagaatgtgt acaatatatg gttttaattc catttttaat
    50221 aattatatcc attgtagatt actacacaat atatgtatat gatataacaa tagttagtgg
    50281 tataatagtt caaggtataa tttttttggc ctttttcaat atagctcaat ttgattatat
    50341 aaatcatata tttggactat tgataggctt tattatacct tatattattg ctaaactaac
    50401 aaaaggatta ggctatggag atgtaggtct ctatagctta tgttgctttg cattgggaaa
    50461 taattatggg ttttatgtga tagttttatc atttatttta gcgtttttgt tttttattat
    50521 tttatacata actaaagtat ttaaagatgt agatataaga aagcaaattc cttttacacc
    50581 ttttatttcc ttgtcgacaa ttttaataat atttacagag tataatatat ttaattttta
    50641 ttataatttg ttatacaaat ttatataaca ggaggtaaga aatgtacgta gtagtagggt
    50701 taggtaatcc aggaaagaag tatgagaaga ctagacataa cgttggattt gatgttatag
    50761 atattcttgc taaagaatac aatattagtg ttactaaaat aaagcataaa gctttgattg
    50821 gtgaagggag agtaggtact gaaaaagtat tattagttaa accacaaact tatatgaatt
    50881 taagtggaga aacattaata gatatatata aatattataa ggttgattta agtaatatag
    50941 tagtagtata tgatgatata gatttagaag ttggaaagat acgtataaga aaaaaaggaa
    51001 gtggaggaac tcataatggc atgaaatcta taactaattg cctaggttca aatgactttc
    51061 caagagtgag agtaggtgta tctaaaccag aagctggtca agacttagca gactttgtac
    51121 tttctagatt tagaaaagaa gaatctgata acataaatga agcattagaa aaagcggcag
    51181 atgctattga ctcaataata agagaaaata tagatatgtc tatgaacaaa tataatggat
    51241 agtgagaggg agatttaaat gaatgatgtt tttttatatc ctttgcaaaa ttcaaaagag
    51301 tataaagata taataaactg tataaaaaat acaaaaggct cattattggt taatggactt
    51361 ttaccagtac aaaaacctca tatatcgtat tctatattta atgatttatc acgacaaatg
    51421 atttttataa caagtagtga tttagaagca aagaaagtat acgaagattt aagtttttat
    51481 atggaagata aagttgaata tttaggtttt caagatattt atttttatca cttggatgca
    51541 aaggacagaa acgaagaagc gaagaaatta aaagtattgt taaaactagc aaataaagaa
    51601 aaaatcattt tagtaacttc tattgaggca gttttaagaa aatacatacc aaaacaagtt
    51661 ttgctcgata gtgtatctca ttataaggtg ggagatagct tagacttaga aaagttaact
    51721 gagaaattag tttcattggg atatgaaaga gtttcaaaaa tagaggggtt tggtcaattt
    51781 agtataagag gtggaattat tgatgtattt tcacttgaat atacaaatcc aattcgtatg
    51841 gaattatttg atgatgagat agattccata cgaacttttg acgtatattc acaaaaatca
    51901 attgataaat tgcaacaatt ctctataact ccatctaggg aatttattta tcccgaaaaa
    51961 actacagatg cattagttaa attaaaaaaa gaaacaacta aaaatactga tgaaggtaca
    52021 tttcaaaata tagattatat atcaagtaag acttattttg aaggtgtaga gaactatata
    52081 gattatattt atccagaaga aaacaaaagt atatttactt atttagcaga tgatgcaata
    52141 gtatttatta atgatataac gagacttaaa gaaagatgcg aaaattatat aaatgagttt
    52201 agagaaaatt ataaattaaa tcttgaaaga ggtctggcta ttaaaaacca aggtaaattg
    52261 ttatatcact atacagattt agagtactta gtaaaagaca agtctgtggt attaaactcg
    52321 ctattgccaa agtctataaa taacttttct ataaaatcta taataaattt tgaaagtaga
    52381 gaagttccta catttaatgg aaaggtagat ttgcttgtag aagaattaaa tcggctgaaa
    52441 tataatggat acaaaataat tttagcaaca aataccttag aaagagcaaa taaattagga
    52501 aaagatttat tggacaaagg cttagaaacg accatttcta aagatagaga tattgaaatt
    52561 aaatcttcac aagttataat tgtacctgca cacataaaca gtggttttca gtataaatct
    52621 ataaagtttg ttgttataac agataacgaa atgataggtg tttataaaag agcgtctaag
    52681 actagcaata aaaaagttaa aaagggaaag aaaatagaat cctttttaga tttaagtgtt
    52741 ggagattatg tagtccatga aaatagtggt gtaggtagat acacaggaat tgaacaaatt
    52801 acagtcaatg ctattaaaaa agattatatg aaaatagtat atcaaggtgg agataatcta
    52861 tatgtgccaa tagaccagat ggacaaagta caaaaatata ttggtgcaga agtagaaaaa
    52921 gttaagttaa ataagcttgg aacaaatgag tggacgaaag caaaagcaaa agttaaaaaa
    52981 gaaattgaag atatgacaaa agacttgatt gagctttatg caaaacgtga aaaaatacaa
    53041 gggtataagt tttcaaaaga tacaccttgg caggcagagt ttgaatcgtt gtttccatat
    53101 caagaaacag aagaccaatt aaaggctata gaagaaacta aaaaagatat ggaatcaagt
    53161 aaggtaatgg ataggctagt atgtggagat gttggttatg gaaaaacaga ggtagctatt
    53221 agaagtattt ttaaagcttg tatggaccaa aaacaagttg ctgtattggt tccaacaaca
    53281 atattggccc aacaacatta taatacattc aaagagaggt ttgaaaatta tcctttgaga
    53341 gtagaagttt taagtaggtt taaaacacca aaacaacaaa aacagattat tgaagatgct
    53401 aaaaaaggat tagtagatat tttaattgga acacatagaa taatatccaa agatataaat
    53461 ttaccaaact taggtcttgt agtcattgat gaagaacaaa gatttggagt aaaacataaa
    53521 gaagctttaa agaaaattaa atctacagta gatgtactta cactttcagc aactcctata
    53581 ccaagaacat tacatatgtc tttaagtgga ataagagaca tgagtgttat agaagaacct
    53641 ccacaagaaa gacatcctgt aataacatat gttacagaga gtaaggaaag cgtaattcaa
    53701 gatgagatag agagagaatt aagtagaggt ggacaggtat tttttgtata caatagagtt
    53761 gaacacattg aagaaatggc aagtatgatt caaaaactcg taccagatgc tagagtggct
    53821 gttgcacatg gaagaatgac ttctaaatca ttagaaaata taatcctagg atttttaaat
    53881 aaagattatg atgtactagt ctgtactaca ataattgaaa ctggtatgga catatcaaat
    53941 gcaaatacaa tgattatata tgatgcagat aaaatgggat tggctcaact ttaccaattg
    54001 agaggtaggg ttggaagaag ttcaagacaa ggatatgcat atcttttgta tgaaaaagat
    54061 aaaactttaa gtgagatagc ggagaagaga ttaaaagcta tcagagaatt tacagagttt
    54121 ggttctggtt ttaaaatagc aatgagagac cttgaaataa gaggagcagg aaatatttta
    54181 ggttctcaac aacatggtca tatggcagtt ataggttatg atttgtacgt taaaatgctt
    54241 aatgatgcaa ttaaaaaagt caaaggtgag cctattgtgg aggaaattga tgttgaaata
    54301 gatttaagtg taaatgcata cattccagat aattatatca aagatgagtt gattaaaatt
    54361 gaaatgtata agaaaatagc ttctattgaa aacaaagaag acatgttgga tatacaagaa
    54421 gaacttgagg atagattctc tgatatacct aaaccagtcc agacacttct tacaatagct
    54481 tatataaaat cgttatgtaa gatattaaaa atagaaaaga taagacaatt aaaagatgaa
    54541 atattattag ttccaataac aaagtataga actaaacaga aaataggtta taatatagtt
    54601 acagaattag aagaattatt agaaaagatg tgcaaggtaa aataacttgt aaatttaaga
    54661 agggatgttt taaatttgaa aaaagtaata acattggtaa tagctatgat tttggtagta
    54721 tctgtgactg cttgcagttc tagtaaagga gaaactgtgg caacagttga aggtacaaag
    54781 atatcatcag atgaatttaa aaaaactata gctctttata aagattctat ggaacaaact
    54841 tatggaaaag atatatggga taaggaagtt gaaaagggtg taaaatacaa ggacaagttt
    54901 aaagatttaa ttcttgacca acttataact acagaagtaa tatattctca agctaaaaaa
    54961 gataacttac ttcctaaaaa agaggatgtt gaaaaaagtt ttaaagaatt aaaagacgct
    55021 atgggtaaag atgaaaaata taaagaacaa cttaagaaat taggtataga tgatgagttt
    55081 ttaagagacc aacaagagaa agatttagca atgcaaaact atcaaagtaa ctttgctaaa
    55141 aagactaaaa tatcagatga agaaatgaaa aaatactatg atacacataa agatgaattt
    55201 aaaaaagatg aggtagaagc ttctcatatt ttattgaaaa cagtagatga taataacaag
    55261 ccactttcag ataaggaaaa agctgaagct aagaaaaagg ctgaagaggc tcttaaagaa
    55321 gttaaatcag gtgaggattt tgcaaaagta gcaaaaaaat attcacaaga tacttcagca
    55381 agtgatggtg gtaaattagg attcttttca aggggtcaaa tggttgctga atttgaagat
    55441 gctgcttttt ctatgaaaaa gggtgaagta tctgatttag ttgaaactca atatggatac
    55501 cacataatta aagtgacaga cagaataaat gagcaaacat catttgaaga tgctaaagaa
    55561 actataaaag accaactgtt gaaaaataaa tatcaagaac aaatagaaaa attaactaaa
    55621 gaagctaagg tagaaaaaga tgaaaaagta ataaataaaa tcacaatcta agacttaaaa
    55681 aaagagtaat atgcttaaaa aagctatatc tggataagat atagcttttt ttgtatattt
    55741 ttcttaacaa tggtaaaaat aaacttaaag taatttatgg agggattaaa aaatatgaaa
    55801 gcaacaggta tagttagaag aatagatgat cttggaaggg tagttatccc aaaagagata
    55861 agaaagacat taagaattag agaaggagac cctttagaga tattcacagc aaaagatgga
    55921 gaagtcatac ttaaaaaata ctctccaata ggtgaattaa atgaattttc gcaagaatat
    55981 gctgaaacat tagctgaagt actaggatat ggagtgttga taacagactt agattctata
    56041 atagctgtgt ctaagcttcc taaaaaagat tataaagaaa aaagtataag tgatgagtta
    56101 gaagcaataa taagtgaaag aacagtaaaa tattcaaaag ataaaaacat tttaccatta
    56161 ttcaaggaag accaaaaaga atatactagt caagttatca tgcctataat tagtgcatct
    56221 ggtgactgta taggttcaat tgtagttgtt tcaaaggata aagatacaat tgcagaaagt
    56281 gaagaaaaat ctttaaaaat tgctgctaac tttttaggaa aacaagttca ataattttat
    56341 cataaagacc ttttacatga aggtcttttg aagtttttgt gtaaaatatt gaatatagca
    56401 ttaaaaatat ggtatattaa agtttgttat ataaacagta tggaggttat gttatgaaca
    56461 ataacaaaaa taaagactcc tttctaaaag gagcccttat acttgggcta gcaggtgtaa
    56521 tcgtaaaaat aatgggtgga ttttttagga ttccccttgg aaacatgatt ggttcagaag
    56581 gaatgggata ctatcaggct gcttatcctg tgtatactct atttttaaca ttagctactg
    56641 ctggatttcc aacagctgtg gcaaaattgg tttcggaaaa agttgcaatt ggaaatttta
    56701 aaggtgcaaa taagatattt aaggtatcac atacagtttt attcattacc ggtataatat
    56761 cattttgtat attatttttt ggagccgact acatagtaac aaacgtaatg aaaaatccag
    56821 gtgcgttata ctctatgaaa gccattgctc cagcattact atttgttcct gcaatgtctg
    56881 catatagagg atattttcaa gggagacaag atatgactaa gattgctgtg tctcaagttg
    56941 cagagcaatt ttttagagtt gtattaggtc ttactttggc ttacttgctt atgaagagtc
    57001 taggtcagac ttttggtgca gcaggtgcta tatcaggggc tacaataggt tcaatagcat
    57061 ctatgcttta tttggtgttt gcttatatgc tagggagaaa agagcgtaga gcagagatag
    57121 atgcaagcca aagatttaaa gatgaaagag tgtcttatat ttttaaaaag cttttaactg
    57181 ttgccattcc tataacaata ggagcatcag taatgccact tgtaaatatg atagataatg
    57241 ttattgtaat aagaagactt atggaagcag gctttacata caaagtggca aattccatgt
    57301 ttggtcaatt aacaggtatg gcaatggcca caataaattt accagcagtc ataacaactg
    57361 caatgagtat gagcttagtt ccagcaattt ctaaagcata tgcattagga aataagtcaa
    57421 aagctagaaa agatactaag agtgcagtta aggtaacttt acttatagta ttgccttgtg
    57481 cgtttggtat ggcttcttta gcaataccaa taatgggtct tttatttcca catgaaccat
    57541 cttctgtagg aactattttg tttactctta ctccatgtgt attattttta ggattaatac
    57601 agacattgac tggtataatt cagggaatgg gaaaaccaat agtacctgta attgctttat
    57661 gtgttggtat gctatgtaaa attgtaataa gttatacttt aacaggtata ccagatatta
    57721 atgtactggg ttcagcattt ggtacagtta cagcatactt tgtggcagcc atgattaact
    57781 tactatatgt taaaaaacac atgaatgtaa acttttctaa aaaagaattt ataataaagc
    57841 catttataac agttatgaca atgtttataa tggttaagtt gagttatggt gctttagttg
    57901 gattcttagg aaacagcata tctacaataa ttgcaatatg tgttggtgga attgtatatg
    57961 tagtagtaat acttggaata ggtggaatta aaaaagaaga gattctaact atgccaaaag
    58021 gtgataaatt atataaattg ttaaaaaaag ttaaacttat aagataatat aggaatatat
    58081 atgcaaataa aggaaatact atacaaatag taaatctcct tatttgtata ataatataaa
    58141 aataaagtga aatttgctaa taggagtgat gttatgggta agataagtat tgtaggtctt
    58201 ggaccaggag actattctct tataagccaa ggtgtgttag aatctttaat aaatagccct
    58261 aaagtttttt ttagaacaga gaaacatcca ataattgata aacttaaaga aactatacaa
    58321 tacacttctt tagactactt ttatgaaaaa gaggaaaatt ttgataatgt ttatttgaaa
    58381 atatctgaat ttatcataga agaatcagca aagggtgacc tagtgtatgc tgttcctggt
    58441 catccaagag ttgcagagaa gactgtaagt ataatagaga gattagccaa tgaaaagcac
    58501 atagcagtag aaatattgcc ttctatgagc tttgtagacg ctatgtttaa ctatttggct
    58561 atagacccat ctgagggatt taaactggta gatgcttttg aaatagaaaa ttcatatata
    58621 gacttggata caagtatgat aataactcag gtatatgata aatttatagc atctaatgta
    58681 aagttaaaac ttatggaaca ttatgactat aatcaagaag tatgtatagt aaatggagct
    58741 ggtgtcaaag atttagaaag taaaaagttt ataaagcttt gtgaattaga cagaaatgaa
    58801 aacttttttg actatttaac tagcttatat atacccaaaa gttctaaaaa gatgtataat
    58861 acagtacatg acttagaaat aatagttaat acacttagaa gtccatctgg atgtgaatgg
    58921 gataaaaaac aaacacatca atcattaaaa aattctgtta tagaggaagc atatgaactt
    58981 tgtaatgcaa ttgataataa tgatatagat gaaatggtag aagagttagg tgatgttctt
    59041 ttacaggtta tattccattg tcagatagga aatgaggagg gctactttga tttaaaagaa
    59101 gtagtaaatg gcatatgtaa aaaattaatt catagacatc ctcatatatt tagtggtgca
    59161 aaattagata tgtctaagtt tgagaaaact tgggaagaat taaagaaaga agagaaaggc
    59221 gaaagtacta taacagatgg ccttagaagg ataccaaaac atttaccagc tcttatgaag
    59281 gctagtaaag ttcaacataa agcagcactt gtcggctttg attgggacaa tgtagaagat
    59341 gtatttaaaa aaattgaaga agaatatcag gaattacttg acgaacacag ggtcgggaat
    59401 ataaaataca taaaggaaga gctaggcgat ttattatttt cgatagtaaa tctagctaga
    59461 tttttagaca tagactcagg agaagccttg aactgtacta cagaaaaatt cataaataga
    59521 tttgacttta tagaaaagag tgcaatgaac ttgaataaaa aattagaaga catgacactt
    59581 gaagagatgg atgagttttg gaatcaggct aaaaaacaat aaaattgtgg aaggaaattt
    59641 gtcaaaaatc tagaactttt atcacaaaga tagaagtcta tattataaac atttttagga
    59701 ggtaaatatc gtgaataaag ctgaattagt atcaaagatg gcagaaaaaa gtggattaac
    59761 aaagaaggaa gcagaagctg cgttaaacgc atttatgagt tctgttcaag atgcactagt
    59821 aaataatgaa aaagttcaat tagttggatt tggaacattt gagacaagag aaagagctgc
    59881 tagacaagga agaaatccaa gagatccaga gcaagttata gatataccag cttctaaagc
    59941 accagttttc aaagctggaa aaggattaaa ggatataata aatggataat tagaaatctt
    60001 gtgaaaaagt gtggataaat ttgccacact ttttctatag aaccaaggaa ggtgataatt
    60061 atgagattag ataaattttt aaaagtatct aggattataa aaagaagaac tgttgctaaa
    60121 gatgcatgtg ataaagggat tgtcactata aatggaaaag ttgctaaatc ttcttcagag
    60181 gtgaatattg gagatacatt agaaatacaa tttggagaga agaagatgaa gtttaagata
    60241 aatgaagtaa aagagcatgt attaaaaaat gatgcaaaag aaatgtacga aattttagaa
    60301 taaaattaat agtcctctag tatattaata gtagtattat tgaaatattt actgggggga
    60361 tattatggaa cagaacataa ctttgaaaga tagatcaaag ctggttattt cgggagtcga
    60421 gcacatatac tcttttaatg acaaaagagt agagctcaaa acttctgtag gcgagatggt
    60481 aattgaaggc gaaaacctag atatgagcaa gctaagtata gacgaaaata taattagcat
    60541 agatggaact ataaattcta tggtatatgc aaagcctaaa aagccacaag agagtttctt
    60601 gaaaaaggta tttagataga tgataccttt tactcaagat gtaagcattt tttatgctac
    60661 tatttatggt ggaatactca taggggtgtt gtttgatttt tatagagggc taagagggaa
    60721 ttttaaattc atcaattatt ttgctataat atttgatgta ttgttttggt ttctagctac
    60781 ggttataata ttcgtaacaa taaaccttac agaatttttt gatttaagat attatcattt
    60841 tgtggctttg tttattggtt ttattttata ctataacacc ataagtaaaa ttgttttatc
    60901 aattatcaat aaaataattc gttttgtgag aaattctttt aaaaaagtta cacattacat
    60961 agtcagtttt ttaaataatt tgtattacgt tataatctat tcactacacc tactatttga
    61021 tattatattt tatataccaa acatatttat agcaacaaga aaaagtataa aaagaaaatc
    61081 aaataaaaaa ttaaagaaca agaaaaaatc aaaacctaag aagaaaaaaa ataaaactaa
    61141 aaaaagggtg taggaaaaat gaacttaaga aaaaaatttt caggacagat tattgttatc
    61201 agtttatttt taggaatatc aatttttagt atgatgacag gatttgtatt tgagtataca
    61261 aaagctaagg aatataaaaa agaaatagca agtctaaata aacaattaaa aaagactgaa
    61321 atacaaataa acagcttaaa gaaagatgaa aaatcatatg aaggagactt agaggatata
    61381 gcaagaaaaa gattgaatat ggtaaaacca aatgaaacag tttatgtaga cataaatcgt
    61441 tgattaaaac ttgctaataa gtttacagat gtattgattt taaaatttaa gatttaataa
    61501 aaaagtcatt cagttaagga tggctttttg tttttattga ggagggaatt tcataatgaa
    61561 agtaggagct atagatattg ggacaaactc aatgagatta ttgatagcag attatagaga
    61621 tgggaatttt ataaacagaa aaaaatttgt taatacaact agaattggtt atggtgtgga
    61681 tagtaaagga tatataaaag aagatgctat caaaagaaat ataaaagcat taaaagaatt
    61741 ttctgataag tgtaatgatg aaaagtgtga aaaaatttat tgtatgggga catctgctct
    61801 tagagacagt aaaaatggag attactttgt taaattagct aaagaagaaa ctggaataga
    61861 tgttgatata gttacgggaa tagaagaatc aaatttgggc tttaagggtg ttttagaagg
    61921 aatacaaggt gatgatacta ttattgttat agatattgga ggaggttcaa cagaatttat
    61981 tgtaggtgat tcagaaggaa ttaagtttaa taaaagtgaa aatgtaggtg ctcttaggat
    62041 gacagagagg tttttgaagc acgatcttat tgaagatgaa gagtttgaag ctatgagttc
    62101 atttatatat ggtgagattg acaaaacgtt aaatcatata aaagacagag gattaaaaac
    62161 tcttataggt ataggaggta cgattacatc attatcagca atgaatcaag aattagagat
    62221 ttactctatg gaaaaaatac ataatagtaa aatacacaaa aaagaaatag aagaaattct
    62281 acaaaaatta ataaagatga cattaagtga taaaaagaac ttaaaagggc tacaagaaaa
    62341 acgtgcggat attataactg ctggtgtaaa aatattgaat ataataatgg aaaaattaga
    62401 aatagaagaa ataaccgtaa gtgaatacga taatttggaa ggcttaatat gtcaaaagtc
    62461 aaaaaaaatg tattaatatt ttttgatttt taaaaccgat tatgacaaaa aaaattactc
    62521 ctctttgtta caattcttaa tataaacaaa agaggaggtt tttttatgca aagaagtgta
    62581 gcagttgtga agaataagac tgtaaaacca aatgtcataa aattaataag cggatatatt
    62641 gattttacta cggcggcatt cgctgtgatg ggatttttac ttagtaggtc tattatagta
    62701 gactctgtag ctcctttagg aattgccttt tttatatgtg catcaaagat tgataagtac
    62761 aagatacctg tattcatatc aacattatta ggaatattgt tatcatctaa tgattttgga
    62821 aatgtagcaa aatatgctgt gtgccttaca atatttatgg ctatgaataa aaaattaaaa
    62881 ttatcagatt caattgctaa ggttgcattt ataggtgcaa taatactact tccaatctcc
    62941 atgggacaag ctttcttttc aaataggtat gtatatggtc ttcttatagc aggagtagaa
    63001 tcaataataa tgtttatatc tatatatgtg ttttcttatg ggataggttt aatggccaat
    63061 gtcaacaata ggatgtctgt acggacagaa gaagccatat caataagttt actgctaacc
    63121 tttagcataa tgggaatagg agatatatct ctgtttggaa tatcaataag gaccatttta
    63181 tcgaccgtat tgatattgct gacctcaata gtaggtggag ctaccatggg agcatctagt
    63241 ggtgtaatta ttggtgtagc atccatttta aataatatga catcagctgt ttatatgggg
    63301 atatattctt tttcaggatt aataagtgga gcatttaata aaataaataa atatttctgt
    63361 atactaggat atattctaag ttggacaata atatacctat atacttctgg tattacttct
    63421 aatatgatgc aattaagaga tatactatta ggttgtttga tagtactagt attgccagag
    63481 cgattattta ataagattga aaaattaata aaaagtaatg tggcttcaaa tgaaatcgta
    63541 tacgattata ttatgagaag caaaaaccta actaatagca gattgaacag tatttataaa
    63601 acttatgatg accttgcaga tacatttgat aagataagag aaaaagacaa agtgctagac
    63661 caaagagaca tagctaatgt aatagatatg attcataatg atgaatgtaa aagttgtagt
    63721 atgagaagaa tgtgctggga gtcaagattt aatcatacat acactatgat atataacatt
    63781 cttgaaaaaa ttgaggagaa aggggagtta agtctaaacg atatacctaa aaattttaga
    63841 aaggaatgta tgaaaccaga gtcaatagtg aaaatatcaa atcactatta caaaatgttt
    63901 gtattagatt atgattggag tgtgaagttt tcagaaagta gaaagttaat agcaaatcag
    63961 ataagaagta tttcaaaatc cattaaatcc ttatctcaag atttagaagg cgacataatg
    64021 ctagatatag aaaaggaaaa aaatatatat gaacagttag aaagatatga tataacagtt
    64081 gataaagtaa gttacttaac aaaaagtaac agtgagtttg aaatatcaat agaaaagaaa
    64141 acttgccatg atggatgtat gtgtgaagat aaaattgtaa atataatttc agacctagta
    64201 ggggaaaata tgtctgttag aaaaatagga tgtcactgtt taggaggtaa atgcaaggca
    64261 acattcgtta aatctcaaaa atataaggct gttacagaag tttcagcaat gtcaagggat
    64321 gggcatatcc tttgtggaga caattacaca tacatggaga taaatgatgg taaatacatg
    64381 atggctataa gtgatggtat gggaaaaggt aaaaaagcat atgaagaatc ttctgccact
    64441 attgatatac tggaaaaaat gatagatgca aaaattaaag atgagatagt cattgatact
    64501 ataaataata tgttgttgtt aaagtcttca gaagagatgt tttcaactct ggatttggga
    64561 attttagatt taaaacgagg ttgtttagaa actataaaga tgggagcgtg ttctacttat
    64621 ataaaaagag aggatggaga agttgactta atatcgtcat catcattacc tgtgggtata
    64681 ttatcagatg taaaaattga tagaaaaaat gtaaaagtta aggaaggaga ctatgttata
    64741 atggtttctg atggaattgt agatgcagga agaaataaca atttaggaga caattggtta
    64801 atatacttct taaagaatat agagactaca aatccaaagg aaatttcaaa tttaatattg
    64861 gatagagcat tagagttaca agcgttacaa attgaagatg acatgactgt tttagttacg
    64921 aaaatatgta caaaataagg tttacaagat tatgtgtata agatgtggat aacttgtgta
    64981 taatatgtta atagactttt gaaaaaagta tagttattaa caaaaataac atataaatca
    65041 acaaaatttg ttgataagta tggcagaaat gttaataaaa tgtaaaaaaa gaaaaaacaa
    65101 aagctattat caaaagagat tcatgttgaa ataactaaat ttctaagtaa agaaaacctg
    65161 tgaatatgtt gattattatg tggataacta ttaattcgat atttatttat atagtatgaa
    65221 taattgaata atatatctaa aaaaagccat cctattatta agtaaactta ttgaaaggat
    65281 ggctttttat gaatagaaaa ttgtgcaaag caataatacc tttatttatt tctatttttt
    65341 gcatgttaat aataagtata aaagctgacc aaggatatca aaagaataat gacagagcaa
    65401 ttactgtcat gaataataat gatactgaag atgatgctga aaaaaaacaa gaaatagact
    65461 atgaaaaaac atgttggaat ttgcaatctt tgtttaaaag tgatgaccaa tggaaaaaag
    65521 aacttaagag ttttgataaa gatactaaag agttgaaaaa ttacataggt aaagtaacaa
    65581 aatcgccaac acatttgtct tttgccttaa acattaaaga aaaacttgat ataagactaa
    65641 ataaactttc tgcctatgta aaattaaaac aagatactaa taaaaattcg tataagtact
    65701 tagatatgaa tgatagtatg agtaaatcct atgggaatta tatggggatt tgttcagatt
    65761 tagagttaga aatactaaaa ttatcaaaca aagattacaa gaaaattatt tcaaataaaa
    65821 atataaatag gaaatatggt gcatatttaa gagatataag aaggaataaa gtacattatt
    65881 tggatgataa atcagaagat attctaagca aagtatcttc aataagtagt cttccaagcc
    65941 aagtgtatga attatttaga aatatggata gaaaaactaa tttgacacca gctcaatatg
    66001 cgagtgaatt agagtcatca gatagagaaa atagaaaaaa agcttatcaa gatgaactta
    66061 taacttacaa tgataatata aatacaattg caggtttaat tactggtcaa gttaaaaaga
    66121 atatttttta ttctcaggaa agaggttatg agtcttcttt agaaatgtac ctggaatctg
    66181 ataatgtaga tgaaaaagta tacaataatt tgataaggac tgtaaatagt aatatggaca
    66241 gtctacacaa atatatagat ttaagaaaaa aagtattaaa attagataag gttcattcat
    66301 atgatatgtt tgtgcctatg gttaaggctg ttgataataa tattaattat gaaaaggcac
    66361 aaagtatagt atattcagcg ttgtcacctt taggaaaaga atacaatgat gtagtatata
    66421 aagctttcaa tgaaaaatgg atagatgttt attcacatga aaataaagta agtggtggat
    66481 actgcttatc tgtttatgaa aatcatccat atatactttt aaattataat aattcattag
    66541 gttcagtttc gactttatca catgagcttg gacatgctgt atatgaatat ttaagttcta
    66601 agaatcagaa ttattttaat tcaaatccgt ctatatttac tcacgaagtt gcatctacaa
    66661 cgaatgaagc attactttac gagatgctta taaaagaagc taaaggcaat gatgaaaaag
    66721 cttattatat aacacagtat ttagacttga taaaagatac tctttataca caaactatgt
    66781 atgctgaatt tgaaaaaact atacacgagt tagtagaaaa aggaaaaagt gtaaacgcat
    66841 tagtattaaa tgatgtttgg ggacaacttc ttaaaaaata ttatggacaa agctatgaat
    66901 tagaccaatt atctaaggtc ggatgggcta gaatcccaca tttttataat agtttctatg
    66961 tctataaata tgctacaggt tgtagtgcag gagtaagttt tgcccaagac atcctaaaga
    67021 atggttcaga taactatatg agctttctta aaaagggaag ttcagattat ccaataaact
    67081 tgttaaaatc aagtggcata aatttaacta atacaaaacc catagaaaat acaatcaaaa
    67141 aatttgatag tttagtagca gaacttgaaa agctattata aacattattg taatccacat
    67201 ggtaaatata tcgaattaat gataaaatat actaaaagtt taaagtccta tcaagatagg
    67261 actttttatt tattaattag tgggagatga ttctatgcaa gttaaagtta aaaaggctgt
    67321 aataccagca gcaggtttag gaactagatt tttgccagct acaaaggcac aaccaaaaga
    67381 gatgttacca atagttgata agccaactct acaatacata atagaagaag ctgtggcctc
    67441 aggaatagag gaaatactaa taataacagg tagaaataaa aaatctattg aagaccactt
    67501 tgataaatct gtagaattgg aacttgattt agagaaaaaa ggtaagaaag aattgttgga
    67561 ggtagtacaa aacatatcta acatgattaa catacattat ataagacaaa aagagccaaa
    67621 agggttggga gatgcaattt attgtgcgag gcattttata ggtgatgagc cgtttgcagt
    67681 aatgttaggg gatgatattg tagataatga tgtaccttgt ctaaaacaac taacagatgc
    67741 atatgaggaa tatagaacta caatattggg tgttcaaaag gtaaatcaag aagatactaa
    67801 taaatatggg ataatagaag caaaaaatat agaaggtaga gtttacaagg taaaagacat
    67861 ggtagaaaag ccagagtcag gaaaagctcc ttcaaatatt gctattttag gtagatatat
    67921 aataactcct gaaatctttg atattcttaa ggatttacca ccaggtaaag gtggagaggt
    67981 acaacttaca gatgctttaa aaatattatc taagaaagaa gctatgtatg catacaattt
    68041 tgaaggcaag agatatgatg ttggggacaa gctaggattt ttagaagcta ctgttgactt
    68101 tgctctaaag aaagaagacc ttaaggaaga ttttataaaa tatttgaaac atgtatgtag
    68161 tgaatttgat aaaaataaca atgtgttata caataataca gatgaaaaaa tagatttaat
    68221 tgaagtcaat gaagctagag aacttgaaat tcaaaaataa ttaatgaaag gtgatgtatg
    68281 gtggcaaaat caagtcagaa aaaaattaat agaataatag ctgttgggat tgtgggaatc
    68341 ctcgtaataa cgagtataac agctgttttg agtatgattg caactatgta ataagataaa
    68401 tgacagcagt tgatatacat aaatataaaa accatatata acttgatgta gtcaaaaact
    68461 tacaatattt tagttatata tggtttttag aatttataaa tgtaaaaaaa aatttttata
    68521 atagttgcat attttaaagg aaaatattat tataagatat aaatatagtg ataaatttat
    68581 aaaaacgtgc taagattgga cttgaaatac agtaatatag taggtaataa tgttttaaat
    68641 tttatttatt gaccataata tataaataat gatattatta gacttaactg tttaaataaa
    68701 acttttcttt ttcatgcctt caatttccaa aataagtatg tatataaatg aatatataga
    68761 tgaggaggat ttttttgatt ttagatgata aagtattaga aggattaggt agtaagacct
    68821 tagttgagct acgagagata gctaaagaat taaaaataaa atcaattact acatataaga
    68881 aaaatgagtt aattgagatt ataaattcca aaagtaaaaa tgaggaaaaa gtaaacgaag
    68941 agactaaaga aaaaaatgaa gatattaaag aagacataaa gaatagaaaa gaaaatatag
    69001 agcgtgaaag tatagaaaaa gaagttgaat ataagagccc taccaaatca tacaacaaga
    69061 aagaaataga tacccaaaat atttcccaaa accaagaaca tagaaatcaa agaaatgact
    69121 ataataagac aacgagtgta aatgatagca ataagtcatc aaatatatct aatagaatgg
    69181 tcagaaataa taataaaaac tattatatgc ctaaacaagt tgatgaatct aagatagtag
    69241 atgaatttaa cacatcaaaa gaggatgaag tagtaggtgt acttgaaatt ctgccagatg
    69301 gatttggttt tttaagaggt tcaaattatt tgtctactga aggagatgtt tacgtttcac
    69361 catctcaaat aagaagattt aatatgaaaa caggagacaa gattaaggga ataactagac
    69421 atccaaaaag tggagagaaa tttagagcac ttttatatgt tcaaaaaata aatgatgaaa
    69481 accctgacac agctatacaa agaaatgcgt ttgagacatt aacaccaata tttccagaag
    69541 aacgacttac actggaaact aatagaaatg aaatagctac aagaattata gatttaattt
    69601 cacctatagg aaaaggacaa agaggattga tagtagcacc tccaaaagct gggaaaacag
    69661 ttcttttaaa aagcgttgca aatagcatag ctaaaaatca tccaaatgtt gaacttatag
    69721 tactccttat agatgaaaga ccagaggaag ttactgatat gaaagaatct attgaaggag
    69781 acgttatata ttccactttt gaccaagtat caagtcatca tgtcaaggtt gcagagatgg
    69841 tgttaaatag agctcaaaga ttagttgaac atggtaaaga tgtagtaatt ttactagata
    69901 gtataactag attggcaagg gcatataacc ttacaatatc tcctacaggt agaactttat
    69961 ctggaggtat tgaccctggt gcacttcatg gacctaaaaa gttctttggt gcagcaagga
    70021 atattagaca gggtggttct ttgacaatat taggaacagc attggttgaa actggttcta
    70081 ggatggatga tgtaatattt gaggaattta aaggtacagg aaatatggag ctacatttag
    70141 atagaaaatt agcagaaaaa agaatattcc ctgcaataga tatttacaag tctggtacaa
    70201 gaagagatga tttattgctt gatgatgaag aaaagactgc tctttggaga ttaagaagag
    70261 aaatgagtaa taattcagta atggaaatta cagataaagt cattgaactt ataaagagaa
    70321 ctaaggacaa taaagagttt gtaaaatcaa taaagaattt gtaaaatcaa taatacaaat
    70381 gcaaatatgg attatataaa ctaatagaaa aatcacttga atggcataat aagttgtgct
    70441 ataataatgt agttgataat gtaaaaagaa agttaatata attaattttt ttaaataaag
    70501 agaagaggtg actataatgc aaaaggaaat acaaccaaaa tacaatccag ttgaagtgcg
    70561 ttgtgcttgt gggaacacat ttgttgctgg ttcaactaag gacgaaataa aagttgaaat
    70621 atgttcagag tgccatccat tctatacagg aaaacaaaag aacatagaaa aaggtggaag
    70681 aatcgacaaa ttcaagaaaa gattcaaaat ggactaattt ttataaaagt ggagttggag
    70741 gaagccaact cctattttat tacaaaaaaa cattcatatt ctactttaaa ttgtcttttt
    70801 gtattataat aataaatatg taaaattgag tattctaaat acaataaaat gaggtgagtg
    70861 gatggcaaaa caagctgtag gtgggcaagc tgttattgaa ggtgtaatga tgcagtcaaa
    70921 agacaaaaga gcggtagctg ttagaaaaag tgacggagaa atagcactaa aagaagatag
    70981 aataaaaagt tgggtaagag ataagaatat agataagata ccttttgtta gaggttcttt
    71041 tgttatgata gatacaatga ttcaaggcat aaaaagttta aacttttctt cagagttttt
    71101 tatggaagaa gctgaagagg ataaatttga tttatttata aagaaaattt ttaaagataa
    71161 ggcaaatgat ataattataa tattttcatt ggtcatagca atgttacttt ctgctggatt
    71221 attcattttt atacctacat tggtaggagg agctttttct aaagtaatgc ctaatgattt
    71281 tatgcttaat ttaatagaag gaatcataag gatagctata ttatttgcat atatagtatt
    71341 gatttcacga agtaaggata tagaaagagt ctttcaatat catggagcag aacataaatc
    71401 tatatattgc tatgaaaatg atttagaact tacagtagag aatgctagaa aatttaaaag
    71461 attacatcct agatgtggta caaatttcct atttatagtt atggctgtat caataatatt
    71521 gtttgcattt tttggttggc caaatccaat tcttagaata tttatgagaa ttatatgtgt
    71581 gcctatagta gcaggtttat cttatgaggt aattagagtt cttgggaaat atgataatgg
    71641 atttactaaa attattgcat atccaggaat gatgttgcaa tattttacaa caaaagagcc
    71701 tgatgatgag caattagagg ttgctttgga agcattgaaa gcagtagtag attagagaaa
    71761 aggatatttg ttatgacgat aaaagatata attattaaat attcagataa actaaaagat
    71821 ataagtgata ctccaagatt agatacagag ttattgttac aaaaaacatt gggtgttgat
    71881 agattatata ttcacttaaa tctgaataaa gagctaactg aagaacaaaa aacaaaattt
    71941 atgggttttg cagaagaaag attaaatgga agaccaatag catatatagt tgaaaatagg
    72001 gagtttatgg gattagattt ttttgttaag gaaggcgtat tgattccaag accagataca
    72061 gaaactttag tagaagaaat aattgaaata tgtagagaaa aaaaagatgt aagtatatta
    72121 gatataggaa ctggttctgg agctattaca ataagtttag caaagtacat tgaaaattct
    72181 aaaatcatgt cttttgatat atcagagaca gcattagaaa tagctaaaaa aaatgctatt
    72241 ataaatgaag ttggtgaaaa aataaagtat attaattctg atttatttac agcaataagt
    72301 gatagtaaca taaaattcga tatcatagtt tcaaatccac catatattaa aaaacaagat
    72361 atagaaactc tgcacaaaca agttaaagat tatgaaccat ataatgctct tgaaggtgga
    72421 gaagatggat tagactttta tagaagaata acagaacaag gtaagaaata tttaaataag
    72481 tgtggaatat tagcatatga agttggtcat aatcaagctg aagatgtaat aaatattatg
    72541 aaaagtaatg gatataaaaa aatatacaca aagaaggata ttcaaggcat tgatagagtt
    72601 gttataggtt acaatatatg atataatcaa caattgatat gttacattta atcgaggtga
    72661 aagtatgtta aaaaaattag aggtattgga agatacatat aaagacttaa gtgaaaaaat
    72721 aggtgatccg gatgtaataa atgatcaaaa agtttggcag aaatatataa aagaacatgc
    72781 tgacttggaa cctattgtta tgaaatacag agagtataaa agcgttttag atagtataaa
    72841 agaatcaaaa gaaattttac aagaagagtc agatgaagaa ttaagagaat tagctaaaat
    72901 ggagttagct gagatggaag aaaaagtagc acctctggag gaagaaataa aaatactatt
    72961 attgcctaaa gaccctaatg atgataagaa cgttatagtt gaaattagag gtggagctgg
    73021 aggagatgaa gcagctctat ttgctggtga tttatttaga atgtactcaa ggtatgctga
    73081 aagaagaaga tggaaaatag aattattgag tgcaagtgat actggagttg gtggatataa
    73141 agaagtatct tttatgataa aaggtaaagg tgcttattca agattaaagt atgaatctgg
    73201 agttcataga gttcaaagaa taccatcaac tgaatctggt ggaagaatac acacatcaac
    73261 ttctactgtt gcagtattac cagaagttga agatgtagag gttgaaataa atccaaatga
    73321 tttaagaata gatgttttcc gttcttcggg taatggagga caaagtgtca atactactga
    73381 ctctgctgtt agggtaacac atatacctac aggtgaagta gtatcttgtc aagatggaaa
    73441 atcacaatta aaaaataaag agcaagcttt aaaaatatta aaagctagac tttacgataa
    73501 agcattggca gaacaacaca aagatatagc agcagaaaga aaaagccaag tcggaacagg
    73561 agacaggtca gaaagaataa gaacatataa tttccctcaa ggtagaataa gtgaccatag
    73621 aataaattta actttatata agttagatgc attcttagat ggagatatag atgaaatgat
    73681 agatgcttta attactgttg accaaacaga aaaaatgact gcaatataag taatgtttta
    73741 aagaagctgt ttcttcctag aaattatttt ctattttgaa acagctattt tgcattttag
    73801 gtcatgttat catattctat tgtatataat tgttatatac aagtatagga gggttatatg
    73861 atactaaaag taacaataat tgggcttttg gcaggtgtta tagggacagg attaggagga
    73921 gtaatatcag ccatttttaa aagagaggtc gataaatatc taagtttttt tatgggatta
    73981 tctggtggaa taatgttggc tgtagtggtg tttgatttaa tgaaagaatc catggacaaa
    74041 atggggataa tcaatacagt tatatttacg tttgttggag ctctcataac tatgtacata
    74101 aaaacaaaat tagatgtgtc tggaaatatg gcatctggat atcttatatt cataagtata
    74161 ttactacata atttaccaga aggactagcc attggttctt cttttatgtc aactgaaagt
    74221 ttaggtatta cacttgctat agttataggt ctacataata taccagaagg gttagctatg
    74281 gcattaggct tagtttgcaa taaaatgaaa ctaagtaaag ttattttgtt tactgtaata
    74341 gctggattac ctatgggtct aggaagtttt ttaggtgttt attttggagg agtatttact
    74401 tctcttatag gagtatttct tgctacagca ggaggtacta tgatgtatgt tgtattggaa
    74461 gaaatttttc cacattcaaa aagtgtgtat tgtataattg gtttcttgtt aggtacaatg
    74521 attgtaaatt atatataaaa ttaaaatgaa agcaggcata caaaagatga aaactattat
    74581 aagtaatatt gatataaata atattgatta tgaggaaata aaaatacaag caaaacttct
    74641 tagagaaggt aaaacagtta tttttccaac tgagacagta tatgggttgg gtgcaaatgc
    74701 attagatgaa aatgcagtaa agaagattta tgaagctaaa ggaagaccta gtgacaatcc
    74761 attgatagtc catatatatg aaaaagaaga agtatatgac ttagccaaag atataagtga
    74821 taaagctaaa cttgttatag aaaagctttg gccaggacct ataacaatta tattaaataa
    74881 aaaagatata attccataca aaactagtgg agggcttgat acagttgcaa taaggatgcc
    74941 ttctaatgtt attgccaggg caataataaa agaagctggt atacctattg cagctccttc
    75001 tgcaaatatc tcaggtcgcc catctccaac aaaagcaaaa catgtatatg aagagatgaa
    75061 tggaagagtg gatggaatag ttttaggagg agacagtaat tttggattgg agtcaactgt
    75121 attggattta acagaagaga ctcctatgat actgagacca ggaagtataa ctaaagaagt
    75181 tttagaggaa cttcttggag aagtaaagct tgacccatca ttaagtaaaa aagaagataa
    75241 tcaaaaagct aaagctcctg gaatgaaata taaacattat tctccaaatg cagatgtata
    75301 tataatatct ggaaaaagag aaaatgtagc aacaaagatt aatgatatga taaaatctaa
    75361 tagagacaaa ggtctaaaga caggtgtaat gtgtattagt agaaaccgag agttttatga
    75421 tggagaagta atcgatttag gaaactctct tgaagaagtt gcaagtaatc tgtttgatgc
    75481 tcttatagaa atggacaaaa agggtgttga tgtcatatat tcagaagagt tccctaagac
    75541 tggagttgga caagcaatta tgaatagact actgaagtca gcaggataca aagtgataaa
    75601 ggcttaagag ggagttgtaa aatatgaata tacttattgt gtgtacaggt aatacttgta
    75661 gaagtcctat ggctgaggct atactaagga aagcaattaa agaatctgga agaagtattg
    75721 aagaatattc tatatcatca gcaggtatat ctacagcaaa tggaatgggt gcttctgaaa
    75781 attctataga agtactaaaa gaaatcggta tagacttatc aaatcataga agtaaagtaa
    75841 ttactaaaaa attaattgat gaatcagata taatactaac aatgactaaa tctcataaag
    75901 aaattttagt acaagcagtt ccaaaatgca aagaaaaagt gtatactttt aaagggtttg
    75961 caaataaaaa tgaggaagat atatctgacc catttggtgg aaatttggat atttatagaa
    76021 gcactatgag agaaataatg tattctgtca acgaaatagt aaaaaaaata tgaaacggag
    76081 gataaacaaa tgaagatagg attaggctgt gaccatggag gatataattt aaaaaaagaa
    76141 ataataagct atttagaaag taaaggtata gaatgtgtag attacggaac taataatgct
    76201 acagattctg ttgattatcc tgtttatgga gaaatagttg caaattcagt tataaataaa
    76261 gaagtagatt atggaatatt atgttgtggt acagggatag gaatatcttt agctgctaat
    76321 aaggttcctg ggataagatg tgcagttgta tcagatgtat tttctgcaaa aatgtcaaaa
    76381 gcacataatg atgcaaatat gttatcatta ggcgaaagag ttttaggaaa aggtctagca
    76441 cttgagatag ttgaagcatg gattaatacg gattttgaag gtgatagaca tgctagaaga
    76501 gtaaacatga ttaaatcaat agaagaaaaa cataataaat aataaaaatt acagttttat
    76561 caggaggaat tatcaaaatg agcaaagtgg tagagacaaa ccatccatta atacaacata
    76621 aattaacttt aatgagagat aaaaatactg gttctaaaga ctttagagag cttttaactg
    76681 aaattgcaat gttaatgggg tatgaaataa caaaagatat accattaaaa gatgtagaaa
    76741 tagaaactcc tattcaaaaa acatcatcta aagtagttgc aggtaaaaaa ttagcaataa
    76801 ttccaatttt aagagcaggt cttggaatgg tagatggatt agtgagctta atgccagcag
    76861 caaaagttgg acatgtagga ctatatagag acccagaaac attaaaacca gttgaatatt
    76921 attgtaagct tcctcaagac ataggagaaa gagatataat agtagttgac cctatgcttg
    76981 caacaggggg ttctgctgta gcagctatag atttacttaa gtctaaagga gctaaaagta
    77041 taaaattagc taatttagta gctgcaccag aaggtatagc agaagtgcaa aaatatcatg
    77101 atgatgttga tatatatgtt gcatcagttg acgaaagatt aaatgaacat ggatatataa
    77161 ttcctggtct tggtgatgct ggagatagat tgtttggaac taaataaaaa taaataacta
    77221 taaatattta ttagggactt tcttatatag tgtatataat tttatgtaag aaggttcttt
    77281 tttatatatt ttttctcaaa ataggaatta ttgaattgat aaatttctcg aattgagaat
    77341 aaaaagtttt taccaattaa aaaagattgc ttattttaca aggttttata gaatagtagt
    77401 ctattttaat gtggcatgtt agttgcttac gattaagatt ataggtatta agtgtattag
    77461 ttaaattgag aattgaatat taataatatt attgggagtg gtaatacatg aagaattgta
    77521 tagtagtaag aggggctgga gatttagcaa cagcagttat tcataaatta cacaacagtg
    77581 gttttaaagt agttgcgtta gaaatagaag agccattagc tataagaagg caaatttctt
    77641 tttgtgaggc tgtttatgaa aaaaaagtaa ctgttgaagg tgtagaatgt atattttgca
    77701 atactgaaaa agaaatagaa gaagttttat ctcaacataa agtagccttg attatagacc
    77761 caaaaggaga aaaattatct aaattaaatc caatcgtttt ggttgatgga atactcgcta
    77821 agaaaaactt aggtacaact aaagatatgg caccacttac aatagcttta ggtcctggat
    77881 tttgtgcagg agaagatgta gatgttgtta tagagacaat gagaggtcat aatctaggaa
    77941 gaataataac taatggtaga gcagaaaaaa atacaggagt accaggagca ataaaaggtt
    78001 tttctaaaga gagagttatg cattcacagt atgatggcat aatggaaaat gtatgtaaga
    78061 taggtgatat agttgaaaag ggagacctac tttgctatat taataattat gaaaaaaaac
    78121 atgaagttag agcaacaata tctggagtcc ttagaggttt attaaaggat ggagcaaagg
    78181 taaacaaaaa tttaaaaata ctagacatag accctagaaa agaagaagtt aagaatgctt
    78241 ttacaatatc agataaagct agatgcatag ctggaggggt tttagaagcc atactaaaca
    78301 atgggattta tccccaaaat taatttatat tagataaagc tattaatatt ttattaagat
    78361 gatataataa atttaataga ttaaagagag catatgacgg gtatttaaaa tttaaatggt
    78421 aaaaatgctc tttttttatt ggacattcaa ttaacatgtg tatataatat aaaaataagt
    78481 atttatttag gttgaaatct aataaatata taataccagt acataagcaa agaggagaaa
    78541 agtaaattat gagaccatca tgggatgaat acttcatgga aattgcagaa gtagtgaaaa
    78601 agcgttcaac ttgtattaga agacaagtag gagctgtaat tgtaagagac aaacaaatat
    78661 taacaactgg atataatggt tctccgagaa atcttgaaca ctgtgaaaat attggatgta
    78721 agaggcagga attaaatatt ccctcaggag aaaggcatga attatgcaga gcattacatg
    78781 ctgaacaaaa tgcgataata caagctgctc ataatggtat tagtgtagat ggggcaactt
    78841 tgtatgttac tacaagacct tgtgttttgt gtgcaaaaat gtgcataaat gcaggtatat
    78901 tgaaaattgt ttatgaaggt gattatccag atgatatgtc tacagaatta ttaaaagaag
    78961 caggaataga actcataaaa ttttagtgga taaaatttat aagacaataa atgtcaaatt
    79021 atgacactga aatacaatgg tatcaaatga ttaaaagaaa gtatttgaaa aatcatcaga
    79081 ttagtagtaa gatatatttt ataattaaat aaatttatga gatagattaa ttacatgtta
    79141 tttattttat aataatgagg gatactattt atgagtaaaa gaaatacaca tacagaaatt
    79201 gcaaagttgt ttagtttaat aagtcaaata ggattgatga ttgtaatatc aatattagga
    79261 tgtactttct taggaaaatt tttagatagt aaattgaata ctactccagt tctgacaata
    79321 atatttttat tgttgggtgt tggaggtgct tttagtggtg tttataaaac tctaatagta
    79381 tatacacgaa ggaagtgata tattggatat aaaattactt aaccaggtaa ggtcagtaac
    79441 aaaaggtata gtaatatttg atgtagtttt aattgtgcta atgttgataa catcaacatt
    79501 aagtaaacca gtattattag gacttatatt tggctctata atagctatgt taaattttag
    79561 attattggcg atatcactgg aaaaatcagt gacatttcct gctgggaagg cacaagctta
    79621 tgcatcagca caatatgctg ttagattatt tataatggca gttgttctaa ttgcatcagc
    79681 tacagtacca catttaaata taatcggaac agcattggga ttattgagca caaagtttgt
    79741 catattatca aaaaacttta taaataaatt aaagaggaag gaggcataag tatgaatcaa
    79801 gcgcattatt atctcatagg aaactttaag attagtgaaa caatactagt aagttgggga
    79861 ataatggcct ttttagcgat agcatcttat tttttgacta gaaacttaaa aaaagttcca
    79921 actagtaaag ttcaaatatt cttagaattt gcagtaggtg gtcttgctaa aatggttaca
    79981 gatgttatgg gtaaaaatac agtaaaaaga atgccatata tgataccata cataggaagc
    80041 ttgtttttat ttttcgcatg ttcaaattta agcccattac ttggattaag gtcaccaaca
    80101 accgacttag acacaactgc tgcatgggca atgattacat tttttatgat ttattttgca
    80161 ggagttaaat ttaaggggtt atcatacttt aaagaattgg ctcaaccact tgccataatg
    80221 ttaccaatca atattatagg tgagttagct agaccaatat cattaagttt ccgtccattt
    80281 gggaatattt taggtggaac aataataatg ggtctgtttt atcaactttt aggttttata
    80341 tctagtttaa taccaggatt atcaatacca attggagaaa tattaatacc agtcccatta
    80401 cacttgtact ttgacttatt tgcaggattg ttacaagcat atatatttat aatgttaaca
    80461 atggtattta tatcaagtgc aggagagtta gattaagaaa tcaacttata ttaagataaa
    80521 aataaaataa tttaaaaaat taaagtttta aggaggaaat aattatggaa acagcaatag
    80581 tagcggcagc atcagcaata ggagcaggga tagcagttgc aacaggtata ggtgcaggta
    80641 taggtcaagg tatagcagca gctaaagctg cagaagcagt aggaaaccag ccagaagcta
    80701 aaggtgatat aacatcaact ttattactag gagttgctat agcagagtct tcagcaatat
    80761 atggtttggt tatatcaata atacttctat tcgtaaatcc attctttaaa tacttaggaa
    80821 tgtagattta gtccttaaat attttgagat aggtttatag gtaaatcatc tcaaacttat
    80881 aatcatgaga tgaactttat catctcgtga ttataagtag ttatgattta tggaaaggag
    80941 gataattatg gaaaaagcac tagtaggtat aacgtgggaa tttgtgttcc aaattgttaa
    81001 tacttttata atatttttac ttctgagaaa gcttttattc aagccagtat taaatataat
    81061 tgaatcaaga gaaaatgata ttaaaagtga tttggcagaa ggcgaaaaag caaaaaatga
    81121 aggtttagct ctgaaaaaag aatatgagtc aaaaatcaat tttgccaaag atgaaggtca
    81181 agaaatcata aaacaagcaa ctataagagc agagcagaaa tcagatgata tagtaaatac
    81241 tgcaaagaaa gatgctcttg atataaaaga aaaagcaaac aaagatatag aacaagaaag
    81301 acaaaaggtt ataaatgaaa tcaaaaatga tatatctaac atagcactac ttgcagcatc
    81361 taaagttatt gaaaaagatt tagataaatc taaacatgaa gaattgatag aaaactttat
    81421 aaaagaggta ggggaagcta aatgataaat gtaatagcaa atagatatgc cgaagcccta
    81481 tttcaattag gagaagaaga aaattcaact gatgtcttat tcaaagaact agaaaaagta
    81541 gtagatatga tgactaaagt tagtaaagat ttctacaaag ttttaaaatc accattagtt
    81601 tcaaaatcag aaaagaaaaa cttggtagaa attattttta gtaaggaagt aagttctaac
    81661 ataaaaaact ttttaaaagt tttagtagat aaagatagaa tatcatattt agaagatatc
    81721 gaattagctt ataaagaatt attaaataag aaaaacaatg taattgatgg agtagcaata
    81781 agtgctattc caatgagtga aacagatatt aaagaacttg aagtcaaact ttcaaataaa
    81841 tacaacaaaa atgttactat agaaaatgtt gttgacaaga ctatactagg gggagttcta
    81901 gttagaattg gaaatgaaca aatagatggc actgtgaaaa ctcgtcttga taagatgaaa
    81961 gaaaagctat ctgaagtaat atcttaagaa tggcggtgaa cccatgaact taaaacctga
    82021 agaaataagt tctataatta aacagcaaat aaaaaattat gagaataaag ttgagttgac
    82081 agatacaggt agtgttttaa cagttgggga tggtatagcg agtgtatatg gattagaaaa
    82141 agctatgtct ggtgagttgc tagagttccc aggtgaaata tatggtatgg cacttaactt
    82201 ggaagaagaa gtagttggag ctgttatcct tggagatgac agtgaaataa aagaaggcga
    82261 tatagttaag agaactggaa gaatagttga agttccagtt ggagaagctt taataggtag
    82321 agttgtaaac tcattaggtc agccaataga tggaaaagga cctatagcgt acacaaaaac
    82381 tagaccagtt gaatctgagg cacctggtat aatagataga aggtctgttt atgaaccatt
    82441 acaaacagga atcaaatcaa tagattcaat gataccaatt ggtagaggtc aaagagagtt
    82501 aataataggt gacagacaaa ctggtaaaac atctatagtt attgacacta tactaaatca
    82561 aaaaggaaaa gatgttatct gtatatatgt agcaattgga caaaaacgtt ctactatagc
    82621 tcaattagtt agctctttag aaaaaggtgg agctttggat tatacaatag tagtttcagc
    82681 aacagcatct gaatcagcac cacttcaata tatagcacca tatgctggag cagctatggg
    82741 tgaagaattt atgtacaatg ggaaacatgt acttatagtg tatgatgatt taagtaaaca
    82801 agctgttgca tatagagaaa tgtcattgtt acttagaaga ccaccaggac gtgaggcata
    82861 tcctggagat gtattctatt tacattcaag attacttgaa agagcagcta agttatctga
    82921 tgaattgggt ggaggttcaa tgactgcctt gcctataata gaaactcaag ctggtgacgt
    82981 ttctgcatat ataccaacaa atgttatatc tataacagat ggtcaaatat acttacaacc
    83041 agagttattc tattcaggtg taagaccagc agttgaccct ggtatatcag tatcaagggt
    83101 tggtggttct gcgcaaatta aagcaatgaa aaaagttgca ggaacattaa aacttgcata
    83161 ttcacaatat agagaacttg cagcattctc acagtttggt tctgacttag atgaagatac
    83221 taaaaagaga cttgctcaag gtgaaagaat cgttgagata ttaaaacaag gtgagcatca
    83281 accaataaaa gttgaaaatc aagttatgat aatatatgct gttataaata atcatttaga
    83341 ggatattccg atagataata tagctagatt tgaatcagaa ttgtatgcat ttgtagataa
    83401 taattatccg gaaatatcaa gaaaaatatt aggtggagaa gacttcactc atgatttaac
    83461 agatgcaata aatgaattta aagaaaagtt tgttgttgaa gtataatcct ttttaaaaaa
    83521 ggaggtaaat taattggcag gagctggaat caaagcaatc aaaacacgta tgggaactgt
    83581 tgaaagtaca aagcaaataa ctaaagcaat ggaattagtt gcatcttcta agcttagaaa
    83641 agcaaaagaa aaggctgaag attcaagaga atattttaat actttataca atacagtaaa
    83701 agatattgcc caaacaacac gtggaattag aaatgaattt ttaaaagaaa gagaagtaaa
    83761 aaataaatgc tatgtagtag tagctggaga cagaggactt gcaggtggat acaattctaa
    83821 tgtattaaag gaatctgtct ctcatatgaa aggtaaaaag gaaacagtga ttactgttgg
    83881 aaagaaagca catgaatttt tttctaaaag aaactacaat atagcaaaag atataaatag
    83941 tgttgaagct tgtggatatg aagatgcgac agaaatttca caaactatta ttgacctgta
    84001 taaaaaaggt gaagtagatg aagtttatat tgcttataca aaatttaaat ctgctttatc
    84061 acaagaagtt gaaattttga aattgcttcc attagtcttt gaaaaagata cagacgaaca
    84121 aggaatggca gtaaaagaag aaaaacaaaa tagatcaaaa gtacaatata taccatcagc
    84181 agaagcagtt ttaagttata ttgtacctca gtttatatca ggtacagtat atggtggaat
    84241 tttggaatct tttgcatcag agcaaggtgc tagaagaact gcaatggaat cagccacaga
    84301 caatgcgaat gaaatgctat ctaatttaga gttaagttat aacagagcaa gacagtcagc
    84361 tgtaactcaa gaaataacag agatagttgg tggagttgaa gctctaaaat agggaggtta
    84421 ggaaatggca aatgtaggta aagtagtaca gattgtagga gctgtactag atgttaagtt
    84481 tgatggtgaa caaagcctac ctaacttatt aaatgcgtta gtaataaagt taggagataa
    84541 agaaatagtt gcagaagttg ctcaacatat aggtgatgat actgtaagat gtatagctat
    84601 gagtgcaaca gacggacttg taagaggtat ggaagttgta gatacaggag ggccaataag
    84661 tgttcctgtt ggagatgaga ctttaggtag aatattcaat gttcttggaa aaccagttga
    84721 tgggaaacca gctccaaaat ctgcacctaa attacctata catagaccag caccggcgta
    84781 tgatgaacta gaaactacag cagagatact agaaactggt attaaggtag ttgacttact
    84841 agctccatat ctaaaaggtg gaaaaatagg tctatttgga ggagcaggag taggaaagac
    84901 agttctaata caagagctta taaacaatat tgctaagcaa catggtggta tttctgtatt
    84961 ttcaggagta ggagaaagaa caagagaagg taacgacctt tatggcgaaa tgagtgagtc
    85021 tggagttata aataaaacag ctctagtatt tggtcaaatg aatgaaccac ctggagcgag
    85081 aatgagagtt gctttaactg gacttacaat ggcagaacat tttagagatg agcaaggaca
    85141 agacgtttta cttttcgttg ataatatatt ccgtttcaca caagctggtt cagaagtttc
    85201 agcacttcta ggacgtatgc catcagctgt tggttatcag ccaacattag ctactgaaat
    85261 gggtgcactt caagagagaa taacatcaac taagaaaggt tcaataacat ctgttcaagc
    85321 agtatatgta ccagcagatg acttaactga cccagcacca gctacaacat tctctcactt
    85381 agatgcaaaa acagttttat caagacaaat atcatcactg ggtatatatc cagcagttga
    85441 ccctcttgaa tctacatcaa ggattcttga ccctagtata gtaggaaaag aacattatga
    85501 agtagctaga ggtgtacaat caatacttca aagatataaa gaacttcaag atataattgc
    85561 tatacttggt atggatgaat tatctgatga agataagtta atagttgcac gtgctagaaa
    85621 gatacaaaga ttcttatctc aatcattcac agttgctgag caatttacag gaaatccagg
    85681 tcaatatgta cctgttaaag agactgtaag aggatttaaa gaaattcttg aagggaaaca
    85741 tgatgactta ccagagtcag cattcttatt tgtaggaaca atagaagacg ctgttagaaa
    85801 agcgaaggga agtatgtagt catggccagt gaattttcat tgaaagttgt aactccaagt
    85861 aatacttttt atgatggaga tgttgaaatg atagtagtta gaactacaaa aggagacaaa
    85921 ggggtgttga aaggtcatat accatttgtt tcaggtatac ctgtaggaac tttaaagata
    85981 aaaaaagagg gaagttttaa agaggcgaaa atagcagaag gattcattaa tgtaactcaa
    86041 gataaaactg tcatattaac agaatctgct gagtggattt aataaattaa tttagagtat
    86101 aaaaagtcat tttgaccaaa aaaacttttg ggtaaaatgg cttttttgtg ttttggtgtt
    86161 aataaaataa cgataaaatt gtaagttttt agtgataata aattcacaaa atgtttaaat
    86221 ttactgccaa attatgttgt aattaataag ataaagaaga tttagatagc ttttatgtaa
    86281 gtgaaaaagt cttcatataa gaaatacata taaaattttt ataaaattta aaaaatttgc
    86341 ttagttgtgt agtataata
//
LOCUS       DAMKNB010000007        83289 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.007, whole genome shotgun sequence.
ACCESSION   DAMKNB010000007 DAMKNB010000000
VERSION     DAMKNB010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 83289)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 83289)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..83289
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.007"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            875..1537
                     /locus_tag="PC494_000572"
     CDS             875..1537
                     /locus_tag="PC494_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF3911099.1"
                     /translation="MSILEIKNLNKIYGKSETEVKALSQINLKINSGEFVVIVGKSGS
                     GKSTLLHIMAGLETPTNGDVIIDNINISSLDEKKRSALRKEKLGLIFQSYNLIPVLTV
                     EENIKLPTINIKNKDEAYINELMELLGIKDRRMYLPNQLSGGQQQRVAIARALVNKPS
                     IVFADEPTGNLDTKTESDVLSLLKESQKKYNQTIIMITHNIDITKYADRVIEIEDGFI
                     RE"
     gene            1546..4053
                     /locus_tag="PC494_000573"
     CDS             1546..4053
                     /locus_tag="PC494_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF3911100.1"
                     /translation="MKLNYIVKKYIMGNKKNTLLIVVSIVISTALFLIMNIISEDATN
                     LMINQAKNEFTLKHAQYINPKDEEIKYIENNTSIDKVGKSMLLGISDIGKGQTLQILS
                     QDKVAEELNDIYTLEKGKLPVAENEIAIDSWYIKQKKIKNPIGKRITLDYRRQGIDQE
                     DLYTGEKEFKITGILNSNPILKAQGTSIGLISNDCAIKNIPTKNKYDQVMFTFKKEKN
                     IQRQSQKLIKNGNLNENNIYFNNELLIAISDSMNLKIPYIIVNIVLALATILLIYNIF
                     YILVSNRIKDFGIFRALGFNPNDIFKIMILEVSIYSIISISIGLILGGIIASLSREYV
                     IGVIYNVNYINSIKNQNYINTYIISILLSLGTIIISVSKPLMLSVKTDPMICIRRNNE
                     KVDIKQNSFINKFMIKLFKDYGNIASKNIQRNKKRTNLSIASMVIIFFLMATIYTKST
                     SNFLSDGVLKYWIQGDYLLHNIDISTIRSNNKGYDKNVLQEIKAIDGVTKVNSYRHKW
                     FNIKIDDKSINKNSDYWKKNKDNIEARSEVKDGIKVYNNSFEFLGIEDTDILEDFLIN
                     GKENIDKFSKQPYLYITKKSSDSLNIKKGDRIKVYFDIIDSKTNNFTKTISQEFIVCG
                     IITTLPVTSQVGAEFGGVISTNQFNKFTGISSYERFDIWTSKLANDKYVESELNKITE
                     KTNKGILIPYKAETAEYEKIDNQKTLIMVLVTGIIVILSLFNCCNTIVTSINSRSREF
                     ALFRGIGISKHEINKIVKLESYIYIIVSFCISIIPILIVRSIIIKPFESINLINWKFI
                     GAIILIVFILVSIIMITTLKTLNKIQNENFMEEIKTL"
     gene            4384..4728
                     /locus_tag="PC494_000574"
     CDS             4384..4728
                     /locus_tag="PC494_000574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3911101.1"
                     /translation="MYCLSVVLAIYGIYVFINCTEYIYTMLSTKHLTVKGNEYTIINY
                     YMSNFSQYIIFAILLASMGFVIQKIVHMHFSEIELSGNYSTTVRNISDISLDNDNEMF
                     NRGNIENSILKK"
     gene            4966..5652
                     /locus_tag="PC494_000575"
     CDS             4966..5652
                     /locus_tag="PC494_000575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF3911102.1"
                     /translation="MSSILLVEDDLSLIYGLEYSIQKNGFSVDVARTVEEALQIYKEK
                     NYDLLLLDVSLPDGDGFDICKRVREASNVPIIFLTASDEEVNVVMGLDMGGDDYITKP
                     FKLNELISRIKALLRRYNFTSENVTELKSNNITVKLLENRVFKNEIELELTTAEYKLL
                     CLLMKNKNIVLTRKNILDKLWDGNGSFVDDNTLSVYVRRLRNKIEDNPENPKILLTVR
                     RMGYKWNVIK"
     gene            5663..6904
                     /locus_tag="PC494_000576"
     CDS             5663..6904
                     /locus_tag="PC494_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF3911103.1"
                     /translation="MKVFSNKDIKIFFLVIISVLLMFIVVGQIVVINITNDYKSALLE
                     HDYNIAGYLNSMGVDKSKIPAVFTTNEDKYTLKGKEILNTARYDFGTDDSFMPSVKLF
                     QGKYIKTMFLYLFVFFTMIIFILYVYFFKQQNKIEEASYKIDSFMNGNINVRLNTYEE
                     GSLSKLFGSIDAMSTSLNTHILKEKQNKEFLKNTISDISHQLKTPLTALMMYNQILQE
                     ESHNSEIVENFVQKSQNELERIESLIQNLLKITKIDSKTIILNKASVNVKKLITKILY
                     SFETRAEKEGKSISIRGLENTNLFCDYEWISEALSNLIKNALDNTKENDKIMIEWVET
                     PITTIISVSDTGNGIHIEDIHHIFKRFYRSKFSKSNQGLGLGLPLVKSIIEQHNGTIT
                     VESNFLQGSTFTLSFLKLTNM"
     gene            6975..7658
                     /locus_tag="PC494_000577"
     CDS             6975..7658
                     /locus_tag="PC494_000577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF3911104.1"
                     /translation="MDILVVNNLCKTYGNGYTKVEALKDVSFTVSKGEFVTVVGESGS
                     GKSTLLNLLGGLDTPTSGKIFVDGKEICSMKEEKQTIFRRRNIGFIFQSYNLIPELTV
                     EQNIIFPLLLDYKKPDTIYLDEVLTILGLKDRKSHLPNQLSGGQQQRVAIGRALITKP
                     SIILADEPTGNLDSKNSSDVISLLKVTAEKYNQTIIMITHNTNIASTADRILQVSDGM
                     LKDLGVNRE"
     gene            7655..9988
                     /locus_tag="PC494_000578"
     CDS             7655..9988
                     /locus_tag="PC494_000578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HDF3911105.1"
                     /translation="MRSYLELVPQYAKVHKKKNRTTILCIVIAVCLVTAIFGLADMAI
                     QCQKVQFIKDDGNWHIVLKNLNEEAISEISSRVDIAHYGRGQVIDNGEFKSKEILIQG
                     LDEDLAKQLGLEIIKGRYPVVENETLIDVDAVKSFNLKVGDFIKIKLADGRNKNYKIV
                     GEYSSLSSLRASDKHGLMLSILGTQAIKKSETYDYYYITFKDKVNIRKATSDIKNTFN
                     LSDKQIGKNEKLLSIIGQGDSDYSKPLYLTAGGLFILVLIASIIMIYNSFNMGVIERI
                     KFFGLLRCLGASKLQVKKFVVLESLILSVKAIPLGLLLGCIVTIISSIFLKYVNTELF
                     GSMPILKVSFIGIVFGIIVGFLTVILSAIVPAKKASGVSPLSAIRGNLMFKEILTSGK
                     ASKIANAGSSKIDVSMGINHAFSRKKSFILMTSSFAISIVLFLGFSVFIDFMYQALKP
                     IKPEAAHISIVDADFKSVLTKDDINEISNIKGIKKVYSRMMTDVEATYNNKEATSQLI
                     SYEKNQFDWAKKYLVKGEINEDKLESENIGLVEEGHGFNIGDKIYIKNGNSKKEIEVA
                     GILSSISFDVKDKYIGNIITSENTFTSITDIKDYIIIDTQVDEDAPEDLIQNIRNVLD
                     DNLEVRDKRQGNLEAKNSFYTMAVFVYGFVFIIAIISMFNIINSMNISVTSRINYYGI
                     MRAIGMSNKQLRKMVIVESSTYAVSGCLLGSVLGLILHRYIFVSLVTLKFHIDWQIPF
                     DLLFIIVVTMIIITLLAVRKPIKKICELDIIEVVNAQ"
     gene            complement(10096..10658)
                     /locus_tag="PC494_000579"
                     /pseudo
     CDS             complement(10096..10658)
                     /locus_tag="PC494_000579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901678.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(10772..12121)
                     /locus_tag="PC494_000580"
     CDS             complement(10772..12121)
                     /locus_tag="PC494_000580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HDF3911106.1"
                     /translation="MEKAKKLGLFSMILLGINSIIGSGIFLLPGKVYNLAGQNSMFIY
                     IFATLLVLSILLCFAEVGSMFDKNGGAYLYSKKAFGDFIGFEVGTMSWVIRIISWSTL
                     AVGFATALGSFWPESATEYKGYIAAILVTLLSINSLFGIKSTKIMNNVITIAKLVPLI
                     VFIIVGIFFIKFVNIVPSGNVVNSSMGPAIILVFYAFTGFESFIVASGEMENPKKNLP
                     VALITTIFICAIIYILIQIVCMGILGDRLFENSIPIADASSVFLGNYGKVFISVATLI
                     SIFGINIGSSIVTPKCGSSLAEEGSLPAFIGKTNKYGAPYVAIIISLICCIPLVLTGS
                     FEQLAVMSVIARFAQYIPTCLSVIVLRKRTDVKASFKIPFGPVIPMVAILGSLWLLQQ
                     AWAEDISKPITQNRVLIGLGAMLLIAPLYIFMKKNKEIEHKNKSEDSKLYISREKIQ"
     gene            complement(12158..13378)
                     /locus_tag="PC494_000581"
     CDS             complement(12158..13378)
                     /locus_tag="PC494_000581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HDF3911107.1"
                     /translation="MQQALKLKYQTKELGKDFVIESCNSIKPWLINIRRELHKIPELA
                     LEENLTKQKVISYLKEIGIDYMEFTKHNGIMAYILKESADKTICIRADMDALPIEEEN
                     NIPYKSIHSGKMHACGHDAHTTMLLGACKVLHSIKDKLNVNVKFLFQPAEEGFGGAKF
                     LVEDGCLENPKVDYIFGLHVMPHIETGFIETKYDTLNASVDTIKISIKGKRAHGAYPE
                     NGIDAIVTASQIVTSLQTIISRNLEPNNAAVLTIGKIYGGDAHNVICEDVKLEGTLRT
                     LNSKTRNFMIDKIAKIVGDTASAFGCVGTLHVSDENYPAVINEKELVDTVISNTKELL
                     GEEKFILRPNPSLGGEDFSFYTEHCKGAFFHLGCKNEEKGLISPLHTSSFNIDEDCLP
                     IGVMMHVMNTLYFN"
     gene            complement(13588..14865)
                     /locus_tag="PC494_000582"
     CDS             complement(13588..14865)
                     /locus_tag="PC494_000582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009324594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HDF3911108.1"
                     /translation="MPRKERDEKRRDNKGRLLKSGESQRSDGRYAYKYIDTFGETQFV
                     YSWKLVPTDKVPAGKRPCLSLREKIKQIQKDLDDGIDTIGKKMTVCQLYEKYTRQRGN
                     VRKGTQKSRQQLMKLLSEDKLGAASIDSVKLSDAKEWALRMQEKGVAYNTICNSKRSL
                     KAIFYMAVQDDCLRKNPFDFQINEVINDDTVPKVPLTPTQENELLDFMQNDSVYAKYY
                     DEVVILLETGLRISELCGLTPADLNFEKRFVNVDHQLLRSTEDGYYIEAPKTESGFRQ
                     VPMSAAAYEAFERVLKKRRDGKGIEVDGYKDFLFLNRDGLPKTAVNYDAMFKCLAKKY
                     NKCHKEPLPDVMTPHTMRHTFCTRMANAGMNPKALQYIMGHANIVMTLNYYAHATFHS
                     AQEEMERLQAKAKTTAEAKPEATAESAEETKAA"
     gene            complement(14945..15148)
                     /locus_tag="PC494_000583"
     CDS             complement(14945..15148)
                     /locus_tag="PC494_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002607397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HDF3911109.1"
                     /translation="MSNNDVPIWEKYTLTIEEASKYFRIGENKLRRLAEENPTAGWVI
                     LNGNRIQIKRKQFEKIIDSLDTI"
     gene            complement(15582..15824)
                     /locus_tag="PC494_000584"
     CDS             complement(15582..15824)
                     /locus_tag="PC494_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004611627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF3911110.1"
                     /translation="MKQSSYKGKSPLPDFVIDAACAGNAEAVERVLQHYDGYINKLCT
                     RTLYDGSGQPHICIDEYMKRRLQIKLIHSIVSPIGD"
     gene            complement(15831..16262)
                     /locus_tag="PC494_000585"
     CDS             complement(15831..16262)
                     /locus_tag="PC494_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009296628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HDF3911111.1"
                     /translation="MEAIPRKYGEWGQFDRYCKLVLYHEAIDYLREMKCRRDREVSLD
                     ALSPADWDKLSTVDRYSCDSFIFSSHGYDLHIDNELVAEAFASLPKDEQSILILRFVL
                     DLTDEEIGRLMGMSRSAVQRHRTSTLKDLRIKLMAFMPEGG"
     gene            complement(16776..17546)
                     /locus_tag="PC494_000586"
     CDS             complement(16776..17546)
                     /locus_tag="PC494_000586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005361171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HDF3911112.1"
                     /translation="MKKILLIDDSDTYTWCLQKYLQHRGYSVKTACTLKEARAAIQEE
                     MPLVVCCDLDLPDGSGMDFLDEVRAADKELPFILASCHDKDDYEQEAMRRGATLCMDK
                     MKGLLLQDKLVEYAYRQLSGEKAPTFHKLLFVHAEDTNAGVLRAAMLQKGFDLILVPS
                     IGEAKRRIFEDKEIDLILCDVELTDGTAMELFHTLRRVAGMFQMKNPPVRLLPFFILT
                     ENNDLATEYEYRHEGVNDYITAPVNIPELIRRVLFFVE"
     gene            complement(17734..20112)
                     /locus_tag="PC494_000587"
     CDS             complement(17734..20112)
                     /locus_tag="PC494_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016323773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HDF3911113.1"
                     /translation="MTWPFENDTSGITKKLAKKSLQSEKRRNLMVVIAVALAAFLICF
                     TGIVSTSLTQMQRNQVVDTYEAVWLGVEENDIETLKGLPEFERVGGYYMLGEELSEQG
                     YHASYVYCDAQMMEITKAQMELLEGRVPEKANEVVVSEYFLSTYGNNAKIGDTVTLDT
                     ESFHGNYVVTGIMDSANEKEANTCAIILSKAALTEWAGFDPAGYRAYAHFKNSDQLDE
                     ELMTSYCREIAEEYQLPMPKMNSKYFAYASKSFDFALIASVIAIVLIGGYIVIQSIFR
                     ISINDKIKSYGQLRTIGATPKQIKRIVKREGRKLGSIGILIGTVLGVCGGFLLFSKGF
                     NAVSYVATVILTLISSWIMVSVSIRKPVKIAAGISPIEAVRFTPAQKDIRSRKKNIKL
                     NPVSMGIANFKRDRKKTVAIVASLSLGGIILLVVSSIVLLRSPEALARQFFPDGDYKI
                     YLDSEMTEEKVMAAGNPLNEELKQEILSIDGVTDIIPSRQSLHATYKTKIHQAGGMCD
                     MLTDQNYAAVEAALTEGTMPTDSRSIVIDYNVLKQNEDMGVGSTVEISLGEEQPSVSV
                     TISGLYAPAKVYSGHGRMHLDGATLFAPEALFHELHPEITSFDYSWSIVNDPKKTDYV
                     GAELKNIVASHSNIALDEINTVIEYEEMTNSFAFGSMEILSWLVFLFGVINLINTTLS
                     NQIARKQENSILRSIGLTQKQLCKMNICEGLCYALFATLATLIVGLPASIFACRKMSV
                     GAFAGNVVPYKFPVLEMGLFILVLFGMELILSVWTIRRQKKQSLIEQMRVME"
     gene            complement(20127..20792)
                     /locus_tag="PC494_000588"
     CDS             complement(20127..20792)
                     /locus_tag="PC494_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004056668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF3911114.1"
                     /translation="MSILQTIDLKKYYGTEPNITRALDGVNFSVNDGEFVAVVGTSGS
                     GKSTLLHMMGGLDTPTSGNVIVRDKELSKMNDEQLTIFRRRNIGFIFQNYNLVPILNV
                     YENIVLPVELDGDTVDQKFLDEIVHLLGLEDKLKNMPNNLSGGQQQRVAIARALITKP
                     AIVLADEPTGNLDSKTSAEVLGLIKRTSAEFRQTVVMITHNNDIARLADRIVRIEDGK
                     IVE"
     gene            complement(20798..21058)
                     /locus_tag="PC494_000589"
     CDS             complement(20798..21058)
                     /locus_tag="PC494_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009244706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3911115.1"
                     /translation="MELTSTLILNLALLIVPPVALVLVFRQWLARHIRWTVALTALWD
                     VLLFWDELFYYESFGLFAVLILVQLAATGAAAFRFYNKQRKD"
     gene            complement(21252..23792)
                     /locus_tag="PC494_000590"
     CDS             complement(21252..23792)
                     /locus_tag="PC494_000590"
                     /inference="COORDINATES: protein motif:HMM:NF014717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF3911116.1"
                     /translation="MTWPFENDNMKIIKHLSKSSLKANKKRNMAAVLAIILTTMMFAS
                     LFTIGTNIAAALRTQNIRTMGSDGHAAIKYIDDTIYNELKADSSLKEISYGMVVADKI
                     GNPELEGRQIEAWYMDDTGLKFANCMPTEGNIPVAENEVLMDTKTLEALGLPHEIGTK
                     VSLEFYRKGKEYQENFILSGYYESDPLLNIGRIFVSEKYRQAHSSELINTYAVDGSLA
                     GTVSSYVMFKNTFDLSGKLGSLITGHGYQWSENIQNPEAMNIVEASISPAYQSNGIVD
                     DPIMLLSFVVAIAFLVFTGYLLIYNIFQISVIQEIHFYGQLKALGTTKRQLKHYITKQ
                     AASLSLVGIPIGVVLGYFFGCVLAPMVLTGLEVSSDIKAENQASPIIFIGAIIFSAIT
                     VWISTYKPGKVAANVSPMEALRFNDVSGNAKKEKNSTNGGKIYRMAWSNLWRNRKRTI
                     LSVVSMVLGLVLFNTVFIFSQSLDVNKYIAGKLNSDFLVGNSNYFSMQYYWKDAGIQD
                     ELLMGLEMQNGFESGGRIYYARPYDGDMNRLEGFSVQSSNPSNYSIHTDGYPRADVYG
                     IEPFISSNLKVLEGELDLEKFETGDYIIQGILDDEPATEFQVGDKIKLNYYNEKTNAY
                     ETKEYILLAKVKADYSNTSRATTGITFYLPKDEYLSTVQDQSIMSYAFNSTDESEQQF
                     ENILISFGEQTGELQFESKMQLAEEFAGMTKSLTIVGMALSLLIGFIGVVNYANSLIT
                     SIIVRKRELSMLQSIGMSGKQLKLLLVLEGLYYVIGTVIGTLVLSVIISFGIMQPIIN
                     SLTWFQFNFTLIPLLTAYPVLVVLAITIPLITYRSMAKESIVERLRTE"
     gene            complement(23807..24472)
                     /locus_tag="PC494_000591"
     CDS             complement(23807..24472)
                     /locus_tag="PC494_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004056668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF3911117.1"
                     /translation="MSVLQTIDLKKYYGTEPNITRALDGVNFSVNDGEFVAVVGTSGS
                     GKSTLLHMMGGLDTPTSGTVIVRGEELAKKNDEQLTIFRRRNIGFIFQNYNLVPILNV
                     YENIVLPVELDGDTVDQKFLDEIVYLLGLEDKLKNMPNNLSGGQQQRVAIARALITKP
                     AIVLADEPTGNLDSKTSAEVLGLIKRTSAEFRQTVVMITHNDDIARLADRIVRIEDGK
                     IVE"
     gene            complement(24665..25081)
                     /locus_tag="PC494_000592"
     CDS             complement(24665..25081)
                     /locus_tag="PC494_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005362406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3911118.1"
                     /translation="MKKINFCKATTIILIINVILSIVLFFVVPDNIAIQWTGTTPSNA
                     VDSYYIFLVPILSVLFAFSGKPIFTMFLFRLWNRTNEHLVTYLNLCLQVVFLTCEIYI
                     GLYNLCNFNFAISIILIVELMIDVVIGLKLFHNQSI"
     gene            complement(25109..26140)
                     /locus_tag="PC494_000593"
     CDS             complement(25109..26140)
                     /locus_tag="PC494_000593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004083359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF3911119.1"
                     /translation="MKFKNLSVKRLFGRVAIGLVLSMSGITIALFLVTKQIAVLLTGG
                     ALLLCALVGIFVLTQAFGKRLSQFTADLCQTLDHMIAGNEAPQRPEDSETQLARIGHR
                     LARLYQIMQENRRRVDEERQELQTLVSDISHQVKTPVSNLKMATDTLLEKPMTEAERT
                     DFIRGIRSQTDKLDFLFQALVKTSRLETGVIQLDKKPGRLFDTVAQAMSGIVYAAEKK
                     EIAVSVDCPEDLTVSHDSKWTSEALFNLLDNAVKYTPAGGKIAVSVVQWEMYVEIKVT
                     DTGKGISESNQAAIFRRFYREEEVHEQQGVGIGLYLAREIVTRQGGYIKVVSEPGKGS
                     EFSIMLPTK"
     gene            complement(26137..26829)
                     /locus_tag="PC494_000594"
     CDS             complement(26137..26829)
                     /locus_tag="PC494_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016323779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF3911120.1"
                     /translation="MKQILIVEDDSFLNKMLDYNLTADGYGVTSALNARTAADAIRQR
                     EFDLVLLDINLPDGNGFELCKRIKPQHPDTIVIFLTANDQESDQIRGYEVGAVDYITK
                     PFVIGALQRKIKAMFAMLEHHKPAKDIYDDGRLFLDFSEQTASLNGKPLTLSPMEYKM
                     LNLFRKNPRRVLTRGQLLEKLWDIDERFVDEHTLTTSISRIRSKIESDGGAPYIKTVY
                     GMGYQWTGGEAK"
     gene            27050..27418
                     /locus_tag="PC494_000595"
     CDS             27050..27418
                     /locus_tag="PC494_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006060489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF3911121.1"
                     /translation="MANIKDCPGFETFGADVKEARKVKQLSRKTLAEQVNIDWRYLAN
                     IENDGTIPSLPVIIQLIKICGLPVERYFNPEIMREESAQRQRVSHKLKLCPEEFLPII
                     EGAIDGAIQIQQKNDETEGA"
     gene            27647..27976
                     /gene="mobC"
                     /locus_tag="PC494_000596"
     CDS             27647..27976
                     /gene="mobC"
                     /locus_tag="PC494_000596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid mobilization relaxosome protein MobC"
                     /protein_id="HDF3911122.1"
                     /translation="MANRKRKFVLRVPVTPEERALIQQKMAQLGTKNFSAYARKMLID
                     GYIVHIDTGPVRAQTAELQKIGVNINQITRRINSTGTVYAQDLEDIKGALAQIWQLQR
                     SILSSQR"
     gene            27937..29271
                     /locus_tag="PC494_000597"
     CDS             27937..29271
                     /locus_tag="PC494_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005947312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HDF3911123.1"
                     /translation="MAVTKIHPIKSTLKKALDYIENPDKTDEKLFVSSYGCSYETADI
                     EFQMLLDQAYQKGNNLAHHLIQAFEPGETTAEQAHEIGRQLADEVLQGKYPYVITTHI
                     DKGHLHNHIIFCAVDMANQRKYISNRQSYAFIRRTSDRLCKEHGLSVVKPGKDKGKTY
                     AEWDAQKKGKSWKAKLKIAIDAAIPQAKDFDSFLRLMEAQGYEVKQGKFISFRAPGQE
                     RFTRCKTLGEDYTEERITQRIKGIAIDRGPHRRSTREISLRIALEDSIKAQQSVGYAR
                     WAKLHNLKQAANSLNFITEHQIDSYEGLESRLAEISAANDAAASALKDAERRLGDMVL
                     LIKNLSTYKQLRPVALELRNAKDMAAFRRQHESQLILYEAAAKALKEAGVTKLPNLYA
                     LKTEYKKLDAERERLSAQYSEAKQKLKEYGIVKQNVDSILRTAPEKEHTQER"
     gene            29268..29639
                     /locus_tag="PC494_000598"
     CDS             29268..29639
                     /locus_tag="PC494_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009296556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich VLP domain-containing protein"
                     /protein_id="HDF3911124.1"
                     /translation="MNIPRISYPQYRKARRLTHECCNYCNGNCLLLDDGEECVCVQSI
                     SYSLLCRWFKVAVLPLDAALCAEITKGRDEIKRCAVCGAAFTPNSNRAKYCPDCAVQV
                     RRKKEAERQRKRYLLSTHLGR"
     gene            29862..31028
                     /locus_tag="PC494_000599"
     CDS             29862..31028
                     /locus_tag="PC494_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006060485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein kinase family protein"
                     /protein_id="HDF3911125.1"
                     /translation="MNIENYIESQYRELLSCSQINAEYSDLYKSFRNQKLREILMTLH
                     HDLVGLFKTMNERLPTGEHEAHFWAEPSRDLIKRIEIIFSLVSSLKETPLAFQIDPYY
                     LDLLTRCRDFLSSSGGSSLPPNMAKVELYYRLPIFLPLSSITISHKQQDFTFDLKLIG
                     SGSYANVYKYKDTFYNRPFILKRAKKELTDKEVARFKREFDVMNNLSSPYILEVYCYN
                     PDKNEYIMEYMDYTLDGYIAAHNSTLTIIQRKGIAQQILRAFDYLHSKGHLHRDISPK
                     NILIKEYDDTLVVKLSDFGLVKILDSTLTTVNTEFKGYFNDPALVVEGFNTYGIVHET
                     YALTRVIYFVMTGKTNTEKIANQNLRAFVERGLNPDKTKRFQNIRDMISAFKTI"
     gene            complement(31076..31276)
                     /locus_tag="PC494_000600"
     CDS             complement(31076..31276)
                     /locus_tag="PC494_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002573995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposon-transfer assisting family protein"
                     /protein_id="HDF3911126.1"
                     /translation="MYFTVEEENLICLYHNADHRRTAANLRAVLPDMDKEMAALACQT
                     ADKLAAMSDADFAAQRFHFTDE"
     gene            complement(31280..35944)
                     /locus_tag="PC494_000601"
     CDS             complement(31280..35944)
                     /locus_tag="PC494_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018595758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4316 domain-containing protein"
                     /protein_id="HDF3911127.1"
                     /translation="MSYSSYDHDDLEPASTMRIERRIYFESGKADLSEAVKLPLAELL
                     SLRAESAAAEQEVFDRLKEQAAAWEEQAGRTLLLDKALEYARTLPVTHTANQWEVPDE
                     YRHIRSNMVYQMDYSISENTRYDSAAQKSVPYSWTLRWGLYTNAPHGNPTEKITGQER
                     KVFSSREELDKYLNGRIKAHDHYFTEISPAIPKEYADCFKVNGCLLPGYTIEGEEPAK
                     AAELPAQEETAQPQQTVATPERREPVNEVFSIFLDNRAEAQTGGPHGYWLSLPTTAEQ
                     VQEALKEIHITADNQQDLFIGGFSAPEGKPLELPEDLIKAASVDELNFLAVQLQRLDA
                     VELAELNAAMQSPAKMQTIGQLLDYAENTDCFVLINAKDSRSLGEYYLNDSGLFVVPD
                     PWKPAIDTERLGSFIASEEQGTFTDYGYILRTSDEWQRVHEGQPVPEQYRVMAYPAPE
                     ILREESKVQPEAAAPTKAPQPVTPILLNGQNSAERMKEITDRLETGIQELFESERYKA
                     YLTSMAKFHSYSFNNTLLIAMQGGQLVAGYNKWRDDFHRNVKKGEKAIKILAPAPFKA
                     KKEVQKLDAQGRPVMGKDGKPVTEVQEIQVPAFKIVSVFDVSQTEGEPLPSIGVEELT
                     GSVERYGEFFKALEQTSPVPIGFEDIPGGSHGYYHLTEKRIAIQEGMSELQTLKTAIH
                     EIAHSKLHAIDPEAPAIEQADRPDSRTREVQAESVAYAVCQHYGLDTSDYSFGYVAGW
                     SSGKDLKELKASLETIRATAHELITTIDGHLAQLQKERQAQQEQPQAAPLEQAAEQSD
                     PDSVFSKLPPEQQQEMTDSVKAMLQTLIDADLKSTGEVSQGTKEAAQAQGFTIAGDGT
                     LEQAKAPQEAAYRLESGDYLYIQTSETGYDYTLYGPDYKELDGGQLDNPGLSLAEAGK
                     EILAIHELPAGTMEPLTGDRLDDFLEATEQANAIPQPQAWNGIDGLLNGKPFMPEASP
                     ADRAAALIELAEKNAPRLGSEERQLIVAYAEAVGDNDKVIGLINRLCEQGYELQKGQM
                     DSFVKSEIESEIAVANAQRQIAQNPAAEPVVTILWSESPHLKDGQQMPLHEAEAVFKE
                     LDSARRHEQEQPGYTGHWYDKTKFRIDFTMQGQPDSYEGRQDFGDGDGSLIQHIRGYH
                     EYYAQDESWKNHVLHHEGPEAWEADKAQRDMLLHEFVPYMELHCNLAAMEQEARRPLR
                     SGETLTPEQTAYFNAVLDYVKECRPLLNQGQYHLPEPPQLADFDQSLQAYKKQIEAEL
                     EQEAAAAGLTVEEYVASDYKAPAQPNFSIYQVPPGPEGRDFRYRSYEDLQADGLSVDR
                     KNYQLVYTAPLDKDTTLDEIYRRFNIEHPADYKGHSLSTGDIVVFRQDGKQTAYYVDE
                     GADYRQVPEFFAQPEKQLTPDECMTGEQIQTPRGRFYLTDRSREQMEAAGYGFHHQSE
                     DGKYLIMANGTRAFAIPAQQESHIKTAEMSTEQNYNMIDGMMNNAPSMEELEARAKAG
                     EQISLLDVAEAAKAEAKKPKQTRRTTQKQKKPSIRAQLAAAKEEQKKRPPAREKSKEM
                     EV"
     gene            complement(36059..36517)
                     /locus_tag="PC494_000602"
     CDS             complement(36059..36517)
                     /locus_tag="PC494_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008689664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF523 domain-containing protein"
                     /protein_id="HDF3911128.1"
                     /translation="MKILVSACIMGVDCKYNGKNNKNLAAINYLKDKEIICICPEQLA
                     GMATPRPCAEIVNGVVTDENGNDVDLEYKRAVSMALSKIQHEDIELAILQSRSPTCGV
                     NQIYDGSFTGKLISGMGLFAKALKERGIKVIDVEEVESFNLLDCPQLQSI"
     gene            complement(36712..38802)
                     /locus_tag="PC494_000603"
     CDS             complement(36712..38802)
                     /locus_tag="PC494_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009324599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase 3"
                     /protein_id="HDF3911129.1"
                     /translation="MSYQLVIAEKPSVARSIAGVIGADKKQDGYMEGNGYLVSWCIGH
                     LVSLADAGTYDERFKKWRYDDLPILPQEWQYIIPDDKKKQFDTLRSLMERPDVTGLVC
                     ATDAGREGELIFRFVYQMAGCKKPFQRLWISSMEDAAIQDGFAHLKPGTDYDNLYQSA
                     LCRAQADWLVGINATRLFSILYHKTLTVGRVQTPTLKMLVDREAKISSFQKEKYHIVQ
                     IAAGGMEAASERMGNADDAKALKAACETAQTVCVSVTREKKTEQPPCLYDLTTLQREA
                     NRLFGFTAKQTLDYAQQLYEKKLLTYPRTDSQYLTDDMLPTAESLVSGLWPMLPFAAG
                     LDLSPQFGRVLNSKKVSDHHAIVPTMEFVQRGFDGLTEGEKKLLSLVCCKLLCAVAAP
                     HVYEAVTATFTCAGNTFTAKGKTILTPGWKELDRRFKASFKTDADDTAPEPARELPQI
                     TEGQTFDKVTAAVTEHFTAPPKSYTEDTLLSAMERAGADDLPEDAERQGLGTPATRAS
                     ILEKLVQMGFVERRGKQLLPTKDGHNLAYVLPEVLTSPQLTAQWETELTAIAKGQADP
                     EGFMAGIAEMTRGLIANYSQISEDAQKLFQTERVVIGKCPRCEESVYEGKKNYYCGNR
                     SCQFVMWKNDRFFEERGKAFTPKIAAALLKDGKAKVKGLRSMKTGKTYDGTVLLADTG
                     GKYVNYRVEQRGKN"
     gene            complement(38799..39560)
                     /locus_tag="PC494_000604"
     CDS             complement(38799..39560)
                     /locus_tag="PC494_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008689667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4366 domain-containing protein"
                     /protein_id="HDF3911130.1"
                     /translation="MKKSKLFRTLTLAVAAALCMATTTVTAYAGGADPDPVPLPETTE
                     APAEVPEETEEPTTGGMEPEGVPVTPQGNAALVDDFFGDKQLITVTTKAGNYFYILID
                     RANEDKETAVHFLNQVDDADLQALLEDGKKEPEVCTCTAKCQAGAVNTACPVCKNNLT
                     ACNEPEPKPQPEEEQPQEEKPSGMGGLVVFFVVVLLGGGAALYFLKFKKEKADTTGND
                     DLAEYDFGEDEDDEDEAPEPDEDMTSEDGNKEDEV"
     gene            complement(39547..39804)
                     /locus_tag="PC494_000605"
     CDS             complement(39547..39804)
                     /locus_tag="PC494_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003509287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4315 family protein"
                     /protein_id="HDF3911131.1"
                     /translation="MAMNKLERIEKDIEKTKGKIAELQKQLRELEAAKTEQENLQIVQ
                     LVRGLNMTPQEFAAFVRGGALQAAPAPIPDFEQEDSAHEEI"
     gene            complement(39828..41783)
                     /locus_tag="PC494_000606"
     CDS             complement(39828..41783)
                     /locus_tag="PC494_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HDF3911132.1"
                     /translation="MEPLKPRDKVTQHMTRDGLTLDNQTTGESVNVSSREAEQEYTAQ
                     PEGAAEKILERADELHDRHKAKKAAKDAGETVAQATSPVSRLQFTAEERASPELAPYI
                     KKAEKRADKLEAAKEALPKKRVVTKETVYDEAKGKAKSRLYFDKVEKAPPQLKPNPAS
                     RPIQEAGLYLHGKIHEVEHENVGVEGGHKGEELAERQASRMIRSGVHRHKLKPYRAAA
                     KAERKSIAANAEFAYQKSLRDNPELAQAAKNPVSRFWQKQHIKREYAKAARAAGQTAQ
                     GAASTAKTTAAAAKKAAEKSRQAASFAARHWKGALIVGGVGLMLLLVMGGLQSCTAMF
                     GSTGTGLAATSYLSEDSDMLGAEAAYAALEADLQHELDNYESLHPGYDEYRFDLDEIK
                     HDPYVLTSILSALHNGVFTLGEVQGDLAMLFEKQYILTQTIETETRYRTETRTDSEGN
                     TYTAEVPYTYYICNVKLENFDLSHLPIYILTKEQMGFYAAYMQTLGNRPDLFPNGSYP
                     HASTPKEPTYYEIPPEALKDEAFAAMIAEAEKYVGYPYVWGGSSPSTSFDCSGFISWV
                     INHSGWNVGRQTAQGLYNICTPVSPEHAKPGDLVFFVGTYDTAGMSHVGLYVGNSVML
                     HCGDPISYTNLNSSYWQQHFYCYGRLP"
     gene            complement(41803..44208)
                     /locus_tag="PC494_000607"
     CDS             complement(41803..44208)
                     /locus_tag="PC494_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009296643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrgI family protein"
                     /protein_id="HDF3911133.1"
                     /translation="MSKKQKNETSAKAPVKLTRAEKKEIQAVIRKYKGDGKPHSAQAS
                     IPYEAMYQDGVCRVTPRTFSKCIEFTDISYQLAQADTKTAIFENLCDLYNYLDASIHV
                     QFSFINRKIDPKQYAKSFEIRAQGDDFDDIRSEYSDILQNQLVNGNNGLMKRKFMTYT
                     IEADSLKMARARLRRIETDLLGYFKSMGASAWGLDAKERLEVMHSIFHPDGEPFSFDW
                     KWLAPSGLSTKDFIAPSSFRFGNARMFGLGGKYGAVSFLQILSPELSDEMLADFLNTE
                     NGIVVNLHVQAIDQSDAIKTVKRKITDLDAMKIQEQKRAVRSGYDMDILPSDLATYGQ
                     DAKELLKTLQSRNERMFQLTFLVLNTADTRQKLENDVFWAAGIAQKYNCSLVRLDYQQ
                     EQGLMSSLPLGASHIQIERSLTTSSVAVFVPFVTQELFQGGDAMYYGINAKTGNMIML
                     DRKRARCPNGLKLGTPGSGKSMSCKSEILSVFLCTPDDVYICDPEAEYYPLVKRLRGQ
                     VVKLSPTSKNYVNPLDINLNYSEDENPLALKSDFVLSFCELVMGGKNGLEAIEKTVID
                     RAVQVIYRPYLADPKPENMPILADLHKALLDQHIPEADRVAQALDLYVSGSLNVFNHR
                     TNIDIQNRIVAFDIKELGKQLKKIGMLIVQDQIWGRVTQNRSKGKATWYFCDEFHLLL
                     REEQTAAFSCEIWKRFRKWGGIPTGATQNVKDLLSSPEIENILENSDFICLLNQASGD
                     RKILAERLNISPQQLRYVDNSEPGEGLLIYENVILPFKNPIPKNTQLYQIMTTRLGEG
                     ATV"
     gene            complement(44111..44560)
                     /locus_tag="PC494_000608"
     CDS             complement(44111..44560)
                     /locus_tag="PC494_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006060477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrgI family protein"
                     /protein_id="HDF3911134.1"
                     /translation="MAYVTVPKDLTKVKSKVVFGLTKRQLICFGGALLVGVPLFFLIR
                     GRVPTSAAALIMVFAMLPGFLLALYEKHGQPLEVVVRQIVACCFIQPKERPYQTNNAY
                     TALVRQSQMEKEVNAIVQKAKERNERKSAGQADPRRKERDSGRHPKV"
     gene            complement(44580..45443)
                     /locus_tag="PC494_000609"
     CDS             complement(44580..45443)
                     /locus_tag="PC494_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002574003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3911135.1"
                     /translation="MIGDLIGEWIKGILIDGIMGNLSGLFNTVNTKVGEIASDVGSTP
                     QDWNGGIFSMLQNLSETVIVPIAAAILALVMCYELIDMIVEKNNMHDFDSSMFFRWIF
                     KSAFAILIVTNTWNIVMGVFDATQQVVNQSAGVIIGDTSIDFDTLLPDLESRLEAMDI
                     GPLLGLWFQTLVVGLTMNILSICIFLVTYGRMIEIYAVTALGPIPLATLGNAEWRGMG
                     QNYLKSLLALGFQAFLIMVVVGIYAVLIQQIGTADDISGAIWGCMGYTVLLCFCLFKT
                     GSISKAVFTAH"
     gene            complement(45515..45730)
                     /locus_tag="PC494_000610"
     CDS             complement(45515..45730)
                     /locus_tag="PC494_000610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002574004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Maff2 family protein"
                     /protein_id="HDF3911136.1"
                     /translation="MEFFNSAVDTLQTIVVGLGGALCVWGGVNLLEGYGADNPASKSQ
                     GIKQLVAGGGVALIGMTLVPLLSGLLG"
     gene            complement(45827..46054)
                     /locus_tag="PC494_000611"
     CDS             complement(45827..46054)
                     /locus_tag="PC494_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006060453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HDF3911137.1"
                     /translation="MGHSDEWTFADYFKYEKEIYRAIISAAVLCQWIAEHDTPPTDGE
                     AEELAREIDRRLCEAWGEIFSLAVLEWRDGQ"
     gene            complement(46083..47888)
                     /locus_tag="PC494_000612"
     CDS             complement(46083..47888)
                     /locus_tag="PC494_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA
                     transfer family protein"
                     /protein_id="HDF3911138.1"
                     /translation="MKPEMKKLIIANLPYLLFVYLFGKLRQTYRLAAGADLSEKLLHL
                     ADGFSLAFESAAPSFHLFDLAVGVAGAVALRLMVYCKSKNAKKYRRGVEYGSARWGGP
                     KDIAPYIDPVFDNNILLTQTERLTMNNRPKDPKTARNKNVLVIGGSGSGKTRFFVKPN
                     LMQCVSKDYPTSFVITDPKGSLIGEVGQLLVRCGYRVKVLNTINFSKSMRYNPFRYIH
                     SEKDILKLVNTLICNTKGEGEKSAEDFWIKSERLLYSALIGYIWYEAPDDEMNFTTLL
                     EMINASEAREDDPEFQSPVDQMFERLEEKDPEHFAVRQYRKFLLSAGKTRSSILISCG
                     ARLAPFDIREVRELMEDDELELDTIGDKKTALFLIMSDTDTTFNFILAMVQSQLINLL
                     CDRADDKYGGRLPVHVRLILDEFANIGQIPNFDKLIATIRSREISASIILQSQSQLKA
                     IYKDAAEIISDNCDCTLFLSGRGKNAKEIAEVLGKETIDSYNQSENRGAQTSHGLNYQ
                     KLGKELMSQDEIATMDGGKCILQVRGVRPFFSEKYDITRHPRYQYLSDADKKNTFDVD
                     SYLSSLRRKKRRVITEDEPFDLYDIELSEEDFAAE"
     gene            complement(47885..48361)
                     /locus_tag="PC494_000613"
     CDS             complement(47885..48361)
                     /locus_tag="PC494_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003819038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PcfB family protein"
                     /protein_id="HDF3911139.1"
                     /translation="MQEEVDQKTIALAVKTGKLTAQVLQAAIRKYLAARQKGTGKAHH
                     GQQSLRQLKKDGSALSNIEITDANIGLFKPCAKKYDIDFTLRKDRTTHPPRYIVIFKS
                     KQADNLEQAFKEFTAKKLQQQERPSIRKTLAVLKEKAAARSSQQAKEKIKERGLSR"
     gene            complement(48404..48616)
                     /locus_tag="PC494_000614"
     CDS             complement(48404..48616)
                     /locus_tag="PC494_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5348 domain-containing protein"
                     /protein_id="HDF3911140.1"
                     /translation="MKQGALIFDEQTDRYDIRFDLADYYGGLHCGETFDVMVGGRWRP
                     TRIEMAENWYLVGIHADDLSGLRVRI"
     gene            complement(48718..49863)
                     /locus_tag="PC494_000615"
     CDS             complement(48718..49863)
                     /locus_tag="PC494_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009296656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF3911141.1"
                     /translation="MYFTSGSDRAFEQLMQTRPGADHFDSGEAGAPEDCGTCRFYRPH
                     WKYQFCVYEECPYQPGKLTALDGAVKFQVKGVDDEMAVFRVEKNRGYTVMSNHHLRNK
                     DLSLKAKGLLSQMLSLPEDWDFTLKGLSLINREQIDAIRAAVRELEQAGYIVRSRERD
                     SQGRLRGADYIIYEQPQPVPDSPTLENPTLDNPTQEKPTQEKPTQLNKDRSSKEKSIT
                     DGSNTDSIPILSPPSPLGEEAAAPPERKGTGAKSQSAVEIYREIIKDNIEYEHLCQYA
                     KGIDRDMLDEIVDLLVETVCSARKTIRIAGDDYPAELVKSKLMKLNSSHIEFVFDCIS
                     KNTTEIRNIKKYLLAVLFNAPSTINGYYTALVAHDMNTGSWGTPQNR"
     gene            complement(50456..52468)
                     /locus_tag="PC494_000616"
     CDS             complement(50456..52468)
                     /locus_tag="PC494_000616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDF3911142.1"
                     /translation="MKKSVALVNDSRKDLIDFLENNLKLVFGDSININRYFINEINDN
                     DIINDDVILVMSVERLDKIINNILDKKKVIVVRRTFREDKIYNLLSLPQGTNVLIVND
                     SDETTLETISLFYKIGVTNIRPIPYMNDNNYKNIKIAITPGVPEKVPSFISDIFDLGH
                     RYIDISTFIEIINLLQIDSKEIQSNLVKYSEEIISLDTGIKDKYKELFLKIEELDTIL
                     NLSKDGILFTSKDGEINTYNSKVKDILDINEDIYGKYIEDIFVDSLKVLLSEKEILDK
                     VVVFNKKYINVNKKNIYNRDEKMGTYYSLQEITYIKKLEQNLTKKLREKGQIAKYTFK
                     DIKTNSPKMFECIDLAKKVSKSDLSILIRGESGTGKELIAQSIHNNSNRKNQPFIAVN
                     CAAVPENLLESQLFGYDKGTFTGGLKDGKQGLFELANNGTIFLDEIGDMPLELQTKLL
                     RVLQEKQIMPVGSHNVINIDVRIISATNKNLEQMIDNSQFREDLYYRLNTIPINIPPL
                     RERKEDILIIMEDLINKKLVITPEAKKLIQNYMWKGNIRELQNVTSYLNIMCEDIVLE
                     KDLPPNLRSSDNKNTSLKLKYSKNDILNILEILILNKESDVGIGRGLILKALLDKNLQ
                     ITEGKIKKIFEYLKKEELIICSSGRYGSKITQKGEDFYNKLKYKGL"
     gene            52939..53589
                     /locus_tag="PC494_000617"
     CDS             52939..53589
                     /locus_tag="PC494_000617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic nucleotide-binding domain-containing
                     protein"
                     /protein_id="HDF3911143.1"
                     /translation="MKAEKTSIYPIIKNNLNKISIVEYKKGQRFVASDKDLQEVFFII
                     EGVALVECTTRGGNKFLVDIVPENEFIGKISYIYEHNLKCDIFAKTNIKLFRFEKNVF
                     EEFYLKPDFIALFHRKCTRRIYELYKTRMVRELFSCTEVIAYCISNKQENNVCNIKAI
                     RNFSEIYSISRKSRYHSLLKLTEKEIVKKMGNTYEILNYDELHKLAFEVKEFLEDE"
     gene            complement(53729..55105)
                     /locus_tag="PC494_000618"
     CDS             complement(53729..55105)
                     /locus_tag="PC494_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HDF3911144.1"
                     /translation="MQELFSLKDENKRFYKILLSLCIPIIIQNLISTSVNVIDTIMIS
                     SLGETSVASVGVANQFFFLFNMSLSGITGGAGVFISQFYGKKDVSNIRKVTGLTCVLA
                     IVLSFVFVIPALLTPKPIIHIFSYDSEVVKLCIDYFSIAVFSYPLIAVSTVFSTGSRG
                     VRNPKLGMICSAFALVTNVILNYGFIFGNFGLPALGVKGAALATVIARICELILMITY
                     VYLYKKDYILKFGLKNLKAIDKIFIKSFSSKSFPIFVNDSVWAIGTVLYSVAYARAGT
                     SAIAASQIATSTGNFFIMTAVCIASGASIMLGNELGADHIKRAIEYAKKFSILVFSAG
                     LILGIILILNIPLLLKMFSVSDSLASDITKIFFIMGILMALKSFNTLVIIGILRSGGD
                     TKYALFLELGCMWLASIPLTFIAAFKGAPIFVLVLLTYSEEVVKFIFGVPRALSKKWA
                     INIVKEID"
     gene            complement(55121..57034)
                     /locus_tag="PC494_000619"
     CDS             complement(55121..57034)
                     /locus_tag="PC494_000619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HDF3911145.1"
                     /translation="MIVLSCNNLNKSFGIDSILENISFTVNEGDKIGIIGVNGTGKTT
                     LFKIISGIYGYDSGDIYTSKDCEIGYLEQNTNFYSDNTILEEVLEVFKNLIEMESYLR
                     ELEVKISEESTKTNSPIIEKIMDEYSHKLELFSDLNGYGYKSEAKGVLKGLGFSDNDM
                     DKPISILSGGEKTRVLLGKLLLKKPTLLLLDEPTNHLDSEAIEWLEVFLKQYKGTVML
                     ISHDRYFLDQSVNRIFEVHNKKLKVYNGNYSKFVELSKIEKELELKKFEDQQKEIKKQ
                     EESIERLKAYGREKHLKRARSKEKALDKVDVLDKPEAYRKKARIQFTPSVQSGNDVLQ
                     IRDVSMGYGERILFKDLDLDIYRGEKVALIGANGVGKSTLFKIITNELQPLSGNIKFG
                     TNVHVSYFHQEQKTLNLDNTIIDEIWENNTHLTQTTLRNMLGAFLFVDEEVFKKISTL
                     SGGERARVAILKLILSNANLLLLDEPTNHLDIDSKEVLEEALTNYDGTIFTISHDRYF
                     LNTVVDKILVLDENGITEYLGNYDYYIDKKRQIQEMSIIEEKEEKTRTQIKDEKRKER
                     EQREIEKKNRIKRQNIEKEIEKLEIEIEKLDILLCQEEVYSNPDKAKEVSQEKINLEN
                     NLASLYDEWEEFM"
     gene            57170..57802
                     /locus_tag="PC494_000620"
     CDS             57170..57802
                     /locus_tag="PC494_000620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HDF3911146.1"
                     /translation="MLGNKNISMAVIRRLPKYHRYLGDLLDRDIQRISSKELSDIIGF
                     TASQIRQDLNNFGGFGQQGYGYNVEALHTEIGKILGLDRPYNAVLVGAGNLGQAIANY
                     AGFRKAGFEIKALFDANPRMIGLKIREFEVLDSDTLEDFIKNNNIDIAVLCIPKNGAQ
                     EVINRVVKAGIKGVWNFAPLDLEVPKGVIVENVNLTESLFTLSYLMKEGK"
     gene            57941..58480
                     /locus_tag="PC494_000621"
     CDS             57941..58480
                     /locus_tag="PC494_000621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TraR/DksA C4-type zinc finger protein"
                     /protein_id="HDF3911147.1"
                     /translation="MVFVEELWKKAIEFHGHECPGLAIGFKAALAAKKYLGCKQSGDE
                     EIVCISENDACGIDGIQVVLSCTMGKGNLLLRMTGKSVYHFFNRENGKSIRIYVKSKP
                     FEMDREGYKRYLLESDFEEIFEITDTKLRLPEKARIFKSLKCEVCGEFASEQYIRIEE
                     GKKVCLDCFDKYERFYEEY"
     gene            complement(58656..58826)
                     /locus_tag="PC494_000622"
     CDS             complement(58656..58826)
                     /locus_tag="PC494_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004619190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HDF3911148.1"
                     /translation="MAYKITDACISCGACEAECPVSCISAGDDAYVIDAGSCIDCGSC
                     AGACPVDAPQPE"
     gene            59111..60178
                     /locus_tag="PC494_000623"
     CDS             59111..60178
                     /locus_tag="PC494_000623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CapA family protein"
                     /protein_id="HDF3911149.1"
                     /translation="MKNKLVYICIMSLLLFVVGCSNNPNKESTIKKDSKNNQSQVKEE
                     KREPVKKDITISFAGDVTMGNYKGSSYYGSFDHEFKRQGEDYNYFLKNVKPVFEKDDL
                     TVVNLEGPLTTASNAKEKKFAFKGKPGYVNILKSGSVEAVSIANNHSEDYFEEGMKDT
                     QFILDENKINYFGLGKDAVVDVKGIKVGLLGYNGLSTEYNEKNLKQMEDDIKSLKKKS
                     DVVVVYFHWGIELDYYPDKKQKDFAHYAIDKGADLVMGSHPHVIQGIEKYKNKYIAYS
                     LGNFCFGGNKNPSDTDSYIYQQTFTFSDNKLTSIKEPNIIPTSITSSNSRNNYQPKIL
                     DGSEKDRVLNKLEKISKDLNK"
     gene            60348..62249
                     /gene="cooS"
                     /locus_tag="PC494_000624"
     CDS             60348..62249
                     /gene="cooS"
                     /locus_tag="PC494_000624"
                     /EC_number="1.2.7.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic carbon-monoxide dehydrogenase
                     catalytic subunit"
                     /protein_id="HDF3911150.1"
                     /translation="MACNTCKMCESADKKLESFVASKDVETAFHRTEDQKVKCGFGLQ
                     GVCCRLCSNGPCRVTPKSPRGICGADADTIVARNFLRAVASGAACYLHVVENTAKNLK
                     NVGITKGVVKGEKTLNQLAEMFGIESDEKYDKCIKVADKVINDLYKSRDDKMELVEKI
                     AYAPRVKKWKELGIMPGGAKSEVFDAIVKSSTNLNSDPVDMLVNCLNLGISTGLYGLT
                     LTNLLNDVMLGEPVIRMAPVGFNVIDPDYINIMITGHQHSTFANFQDRLKDEDVIKLA
                     QSVGAKGFKLVGCTCVGQDLQLRGEHYQEVFAGHAGNNFTSEAVLSTGAIDIVLSEFN
                     CTIPGLEPIADKYKVKMVCLDDVAKKANAECIGLDRSKLDELSNTLIEKALESYKERR
                     GSIEIDIPKDHGFEQSLTGVSEKNLKAFLGDSWKPLINLIAEGKIKGVAAVVGCSNMT
                     AGGHDVNTVELTKELIKKDIIVLSAGCSTGGLENVGLMSPGAEELAGENLKEVCKTLG
                     IPPVLNFGPCLAIGRLEIVATELAAELGIDLPQLPLVLSAPQWLEEQALADGAFGLAL
                     GLPLHLALPPFITGGKLVTEVLTEKLKDLTGGHVIVNPDPKSSANQLEEIIIDRRKNL
                     GLKDVECNA"
     gene            62242..62715
                     /locus_tag="PC494_000625"
     CDS             62242..62715
                     /locus_tag="PC494_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HDF3911151.1"
                     /translation="MHRIFINKDLCTGCKSCVLACMLKHNKDYDMYTLDLENIDNDSR
                     GHIELDSRHNNPVPILCRHCDEPECVLACMSGAMHKDSESGIVSYDEEKCGSCYMCVM
                     SCPYGLLKPDDRSKQNILKCDLCKDEEYPRCVANCPSGAIELQKEENDELCSVRG"
     gene            62690..63916
                     /locus_tag="PC494_000626"
     CDS             62690..63916
                     /locus_tag="PC494_000626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HDF3911152.1"
                     /translation="MNYVVLGASAAGINAVKTLRELDKDSNIVVISKDENVYSRCMLH
                     HVISEHRTLKQINFVDEDFMEQNNVKWIAGKTVKGIDINKKVVQTEDITVNYDKLLIA
                     TGASSAIPPIKNLRDGNFVYSVRNIDDIYKIKEKAQNSKNVVIIGAGLVGIDALVGLF
                     KYEQLNISVAFMEKYILDRQLDEYTASVYENKFKEKGVKFYPSASIQEIVLDNSKNVT
                     GVAFSNGEVLDADMVIVATGVKPNADFLDGTGIEYDRGIIIDDMCQTTQKDIYAAGDV
                     VGKNAIWPLAVKQGIVAAYNMVGKDKKIEDEFAFKNSMNFMDIPTISIGMNTPVDDSY
                     KVLTRHGINDYKKFVFKDNVIYGAVIQGDISYVGVLTYLIKNKVEIYDLENRIFDICY
                     ADFFNIKENGEFCYSV"
     gene            complement(64055..65242)
                     /locus_tag="PC494_000627"
     CDS             complement(64055..65242)
                     /locus_tag="PC494_000627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HDF3911153.1"
                     /translation="MNITKNFLKDYLEKFGETPFLVRLKDEEEFLIGEGSPQFKVIVN
                     NDISKSELLKSTSLALGEAYINRDIEVEGDLFLTLNLLLKQIDKFNIDNSAVKHLLHS
                     SNSMRHQKKEIHAHYDIGNDFYSLWLDKTLSYSCAYFRNDNDTLYDAQVNKVHHILTK
                     LNLEEGMSLLDIGCGWGFLLIEAAKKYKIHGVGITLSEEQFKEFNARIKEENLQDYLE
                     VRLMDYRELKKSDLMFDRVVSVGMLEHVGRENYELFIKNVNAVLKDGGLFLLHYISGL
                     QESYGDPWIKKYIFPGGVIPSLREMIHICSDYKYHTIDVESLRLHYVKTLLYWQKNFS
                     ENLPKIKEMFDDKFIRMWDLYLCSCAAAFNTGIIDIHQILFTKGIKNDLPLTREYMYN
                     CSK"
     gene            65515..66339
                     /locus_tag="PC494_000628"
     CDS             65515..66339
                     /locus_tag="PC494_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase"
                     /protein_id="HDF3911154.1"
                     /translation="MEVYALVGSSGTGKSFKALEFAYENDIEYIIDDGILIYKNKVLA
                     GISAKQANTTIEAVKRAIFYNLEHRQEVREAIKKENIRKILIIGTSKKMVNQIVERLS
                     IGRVCKFINIQDISTKYEIEIAKQARKEGNHVIPVPAVEIKSMASGLSINSLKRLFRK
                     GNNRNMVVLEKTIIRPTFSYIGKFYISADVIKQIIEYEVYNFGSIDRINKINIENCNN
                     FMNIFVSININDLETIKKIEDIQQTIKKSIEKMTLVNVQKIDINIHKIKKINFLQC"
     gene            66468..67733
                     /gene="gluD"
                     /locus_tag="PC494_000629"
     CDS             66468..67733
                     /gene="gluD"
                     /locus_tag="PC494_000629"
                     /EC_number="1.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-specific glutamate dehydrogenase"
                     /protein_id="HDF3911155.1"
                     /translation="MSGKDVNVFEMAQSQVKNACDKLGMEPAVYELLKEPMRVIEVSI
                     PVKMDDGSIKTFKGFRSQHNDAVGPTKGGIRFHQNVSRDEVKALSIWMTFKCSVTGIP
                     YGGGKGGIIVDPSTLSQGELERLSRGYIDGIYKLIGEKVDVPAPDVNTNGQIMSWMVD
                     EYNKLTGQSSIGVITGKPVEFGGSLGRTAATGFGVAVTAREAAAKLGIDMKKAKIAVQ
                     GIGNVGSYTVLNCEKLGGTVVAMAEWCKSEGSYAIYNENGLDGQAMLDYMKEHGNLLN
                     FPGAKRISLEEFWASDVDIVIPAALENSITKEVAESIKAKLVCEAANGPTTPEADEVF
                     AERGIVLTPDILTNAGGVTVSYFEWVQNLYGYYWSEEEVEQKEEIAMVKAFESIWKIK
                     EEYNVTMREAAYMHSIKKVAEAMKLRGWY"
     gene            67946..68536
                     /locus_tag="PC494_000630"
     CDS             67946..68536
                     /locus_tag="PC494_000630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M56"
                     /protein_id="HDF3911156.1"
                     /translation="MHFKSKDLNLKYLVLFLKIVYWFNPFICIMEKYMDLDCEFYCDE
                     RVLKNCTVQQKQEYALTIVNSMKRGTNFSNKFVAGLNKQSDIIKRVMNMFSEKHKNGI
                     LMALIISLFSSITFFKFDSTSIIEENDFLERLRYTFEGRQEDMFVTIDFTYADTPIKL
                     RKEHEENCRVNGIVPKDSDSIEIIPRFYKDCMDLKK"
     gene            68866..69999
                     /locus_tag="PC494_000631"
     CDS             68866..69999
                     /locus_tag="PC494_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M56"
                     /protein_id="HDF3911157.1"
                     /translation="MSNFILNGIFRTVIVSSLSILLILIFKKNVFKRFSKKFNYYIWM
                     IVVIKLFLPFTYYTFTINILRSKKHININNINLEGFNNVSTISNNIILYTWIITVVVY
                     LIYTIFKYIKLKNLINDLSYDVDDREIVNLYKNILEEFNITKDIKLKYSYEVETPAFF
                     NSCVLLPPHEYKLKELDWIFRHELMHFKSRDLYLKYVILFLKTVYWFNPFIYIMDKHI
                     DLDCELYCDERVLKNRNSEEKKDYALTILNAMRKGSNTSNKFIAGLHKQSDIKKRVMN
                     MFNEKYKNGILMALTLCLLSSITFLKVNSTSIVNLNVLPKGFEDLRTVSSIRFSVIGF
                     TYADAPKNMREEYKINCESLGLIPKDSDKIEVGIEYYDSLLND"
     gene            70915..71937
                     /locus_tag="PC494_000632"
     CDS             70915..71937
                     /locus_tag="PC494_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HDF3911158.1"
                     /translation="MKKKILIPVFASVMALSVSSIVNADEVNDSSQNKDDKTNTELNL
                     GEYKEVKYKVAKIKDGVAIKIREEGQVQNIAYSGDEFTVLGTQGEWVKVKVEDGEGWL
                     ATRYVDISEGVGYTNADKVNLRKDKSESSEVIEELEKGSSLLVLEDNGDWLKVKDGET
                     EGYVKSSYISDKAPVIEEPQVNPSIDQNVDSTNNNQQNNANTNQQNNNSNVPTANSNA
                     VQAVLNLAYSKQGCPYVWGAEGPNTFDCSGFTQYVYRNAVGKNIPRTSKAQSKYGQTV
                     SKANLQPGDLVFFTTNGSGSVSHVGIYVGGGNMIHSPSTGKTVSVTSINSSYYTARFV
                     TAKRIL"
     gene            72233..73153
                     /gene="pyrB"
                     /locus_tag="PC494_000633"
     CDS             72233..73153
                     /gene="pyrB"
                     /locus_tag="PC494_000633"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase"
                     /protein_id="HDF3911159.1"
                     /translation="MLKSRNLIQPEDFSIEEIDEILELAQKIIDNPSKYSRICEGKLL
                     ATLFYEPSTRTRLSFESAMNRLGGRVVGFSEPNSSSASKGETLGDTMRIVSGYVDIIA
                     MRHPQSGAASEAARYTEVPFINAGDGKNQHPTQTLTDLLTIKSLKGTLESHTIGLCGD
                     LKYGRTVHSLVKAMARYKNTKFVFIAPEELKMPDYIKEAIKGHAYYETNNLDDVIGSL
                     DVLYMTRVQQERFEDKSEYERLKNYYILNKAKLEKASKDMLVMHPLPRVNEIDIDVDS
                     DDRAVYFKQAKYGMYVRMALIIKLLGINED"
     gene            73192..73884
                     /locus_tag="PC494_000634"
     CDS             73192..73884
                     /locus_tag="PC494_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HDF3911160.1"
                     /translation="MYKILENIYIGEDMYRMKVKGNFEGKMGQFYMLRAWDTYPVLSR
                     PISIHDIDEEGITFLYKVVGEGTQILSNLKVNDNIKLEGPYGNGYAKVDGKVALVGGG
                     IGVAPLYLVAKNIKNCDAYLGFREDVILEDEYKQVCNKVYTTVGNTFVTDIIDVEKYD
                     YILTCGPTPMMEKLVKMVEGTKTRIMVSLENHMACGVGACLVCTCKTNGGNKKTCKDG
                     PVFWGEDVIFNG"
     gene            73877..74779
                     /locus_tag="PC494_000635"
     CDS             73877..74779
                     /locus_tag="PC494_000635"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HDF3911161.1"
                     /translation="MGNLSVKFGSVEFKNPVIMASGTFGFGKEYNEIYDIQKLGGISS
                     KGLTLNKKPGNNGMRVHETPSGMMNSVGLENPGVQGFIDYELPFFSKLDLVRIANVGG
                     GTLEDYLLGVQMLNDKPIDIIELNISCPNVKAGGMAFGIKNEVAREVVREVRNITKLP
                     LVIKLSPNAEDIVGMAKVCEEEGADGVSLVNTFKAMAIDIKNRRPVFENVYAGLSGPA
                     IKPIALRMVHEVCKNVNIPVMGMGGITKATDAIEFIMAGATCIQVGTANFMNPRIGIE
                     IIDGINEFMDREGIKSLDEIRGII"
     gene            74864..75448
                     /locus_tag="PC494_000636"
     CDS             74864..75448
                     /locus_tag="PC494_000636"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HDF3911162.1"
                     /translation="MSKVDVVDILKKSDALLEGHFLLSSGKHSNRYVQCAKVLRFPEY
                     AAEVLSTVVEQIKDLDIDLVVGPAMGGVIVSYELGRQLGKEAVFTERKDNTMELRRGF
                     EVKKGAKIIIAEDVVTTGKSTMETKRVLEALGGEVVGVACIADRTNHDIGMPIYSAIK
                     LDIQVYESDECPLCKEGKLPVVKPGSREFKELGM"
     gene            75786..78830
                     /locus_tag="PC494_000637"
     CDS             75786..78830
                     /locus_tag="PC494_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SrtB-anchored collagen-binding adhesin"
                     /protein_id="HDF3911163.1"
                     /translation="MKKTWKRLCTGFLALATVVTALPTTPVHAESKQYWTESNERVGI
                     VEKVMNDGSIGSTFNEGHLTVEGEDAYCIDINTDFKNGYKTRADASSRMSIDQISDVA
                     LSIEYVKQYTDSHSGIGKNHAYLLRQLVVWQRLSVHLGWQCDNVRASYDEIPKATQDE
                     VFAGAKAFVKENKGRYECGGYIYSGEGQELGQFWAKLNVGNAKLQKTSSNTSITDSNG
                     NYSIAGATYGVFSDKDCTKQLATLTTDENGNTDVAEVKAGTVYIKELSAPAGYKVDKT
                     VYSLKVEAGKTATLKVSDTPKVTDTLIELFKIDMETQKDNPQGNASLAGAEFTWKYYA
                     GFYNKENLPAEATRTWVTKTIAETDSDGTTHYITKLADAYKISGDSFYMQDGKAVLPL
                     GTLTVEETKAPNGYLLDGAYMQAGDKPEQIKGLYVTQITEDGDLAVLSGSNQFSVSDK
                     VIRGGVKIQKRDLETGDTKPQGSATLKDTAFDIISLNDNAVLVEGKLYKKNEVLKTIH
                     TDIEGVASTSADLLPYGKFRIVESEAPDGYLTDGAKPIDFAITENGKIVDLTDEAHSI
                     YNQIKRGDIEGIKIGAGTHKRLADVPFRITSKTTGESHVVVTDDNGQFSTSADWASHK
                     HNTNAGKTSEDGVWFGTSEPDDSKGALPYDTYIIEEMRCNSNKGFELIPPFEIVVSRN
                     NLVIDLGTLTDEYEKEISIHTTATSKDGEKTILAGKEVTIVDTVKLDGLTKGTKYQLK
                     GWQMLKEENAELLIDGKRVENDYTFVADDEEMKVEISYIFNASALGGKNLVTFEELYD
                     FSNPDEPVKVAEHKDIEDDGQTVLITERIIKIHTTATDKDGNKELEAGKEVTIIDTVT
                     LEGLEVGTQYKLVGWQMLKEENAELLINGKRVESDYTFTADSETMKVEVAFTFDATSL
                     DGKQLVTFEELYDLSNPDEPKKVTEHKDIEDKGQTITFKEKPEEPEKPETPPTPEKPN
                     RPSDSPKTGDSTNVMAFVVMLLASAGGLAGTYLYKRRKMKKS"
     gene            79069..79395
                     /locus_tag="PC494_000638"
     CDS             79069..79395
                     /locus_tag="PC494_000638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HDF3911164.1"
                     /translation="MEMKYVVPDMAQSFGTLEFAGESEPVFERDKNNRRVLARRSYNL
                     YSDVQKGENVVVEIPVQAGEKHFKYEQKVKLVNPKLYGRGYAIGDMGHTDYVLVADDI
                     VAVEEK"
     gene            79411..79800
                     /locus_tag="PC494_000639"
     CDS             79411..79800
                     /locus_tag="PC494_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009319862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HDF3911165.1"
                     /translation="MRLSNGFVIDKEKTFGELKFTAVRDVFLQNEDGTPSTQLKKRIY
                     DLKCSLHGGIIPVSVPPEVPLREFPYNAVVELVNPVADTVSRKTFGGADVDWYVRAED
                     IVLKNKGNQNAGNPQNNNTQGQPKKQN"
     gene            79870..80286
                     /locus_tag="PC494_000640"
     CDS             79870..80286
                     /locus_tag="PC494_000640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF523 domain-containing protein"
                     /protein_id="HDF3911166.1"
                     /translation="MKVLVSSCIMGKNCKYNGGNNLNPKVVEFLKDKEVIEICPELLA
                     NMPTPRPSAEIVNGIVMDINGNIVDEEYRHAVQLALNEIRSMEIDLVILQSRSPTCAV
                     KNIYDGSFTGKLIKGQGLFAQALIEAGYKVLDSEDF"
     gene            80360..81754
                     /locus_tag="PC494_000641"
     CDS             80360..81754
                     /locus_tag="PC494_000641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008787614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HDF3911167.1"
                     /translation="MQKIWNKGHRIRASDKHLVYHFSIGTLLFVFVTVLLLLNIKQLM
                     CTDWEHFSLLENGLTLSPYNFITILIATGVCALVAFLYYRFCYDNFKKLLHRQKLARM
                     ILENKWYEADTVQDSGFFTDLQSRSREKIVWFPKIYYQMEKGLLHIRCEITLGKYQDQ
                     LLRLEDKLESGLYCELTDKTLHDGYIEYTLLYDMIANRITIDEVRAENGCLRLMKNLV
                     WEYDALPHALIAGGTGGGKTYFLLTLIEALLHTNAVLYILDPKNADLADLGTVMGNVY
                     HTKEEMIDCVNAFYEGMVQRSEEMKRHPNYKTGENYAYLGLPPCFLIFDEYVAFFEML
                     GTKESVSLLSQLKKIVMLGRQAGYFLIVACQRPDAKYFSDGIRDNFNFRVGLGRISEL
                     GYGMLFGSDVKKQFFQKRIKGRGYCDVGTSVISEFYTPLVPKGHDFLQTIGSLAQARQ
                     DGTATCEAKGDGTD"
     gene            81938..83134
                     /locus_tag="PC494_000642"
     CDS             81938..83134
                     /locus_tag="PC494_000642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003062030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HDF3911168.1"
                     /translation="MVLNEEQWIKELREKRIAYGISQGRLAVVSGITREYLNKIESGK
                     MKPSKELLETLNKELARFNPEAPLTMLFDYVKIRFPTLDIQHIIKDILKLNINYMLHE
                     DYGHYSYTEHYSLGDIFIYTSADEEKGVLLELKGRGCRQFESYLLAQQRSWYDFLMDA
                     LIDGGVMKRIDLAINDHTGILDIPELAEKCRKREYIGKSRSYKFYQSGELIKHREDDR
                     EYMGRTLYLGSLKSDVYFCIYEKDYEQYVKLGTPLDEADIINRFEIRLRNERAYYAVR
                     DLLTYYDAEQTAFSIINQYVRFVDEEPDKRKNDWKLNDRWAWFIGDNRQSLKLTTKPE
                     PYTLDRTLRWVQRQVAPTLKMLKKIDKGNGTDYMETIEQQAKLTEKHEMIIKQQTTPA
                     KDLVES"
     gene            83147..83281
                     /locus_tag="PC494_000643"
     CDS             83147..83281
                     /locus_tag="PC494_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017143882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3789 domain-containing protein"
                     /protein_id="HDF3911169.1"
                     /translation="MWVLLKDFLLVSMGMGIGVVLMCILNVGKEADCEMKQLKESEDN
                     "
BASE COUNT        25753 a        15734 c        17225 g        24577 t
ORIGIN      
        1 taattgaata aattaaaaat ataatgaaag tttagtttta attcatttat ttaataaaca
       61 tttcaagtaa aataatgttt aaatcagaaa tataaataaa tattattata atcgttatta
      121 aagaccaaaa atcccacctt agaagtttgt atcatatgaa acctttatag attatgaaag
      181 caataatata gtgtatgata tataaaataa gttataaaag tattttttta gatattcaaa
      241 aagacattgt aagttatatt aataatatgg gtatcaacga attttggata taatgagttt
      301 ttcaacttaa agttatgtaa taatgaatgt aaagaatatt taatgaaatc attttgttgg
      361 ttatgtctag ctgaatacaa taatctttta gataaagatt ttatatttga agataggtgt
      421 gaaaaaatta agaagatatt aacatcagca gtttagaggc aaagcatgta aagtaaagtc
      481 tgggtaacta aaagtagtaa tttagattgt aactattgtt ataaatatga aaatgaggaa
      541 acaggaaata taagttagga tgtagaaaat aggttactaa ataaaaagct taattatata
      601 atcaaagaaa taggtatata ctgtacaatt tcatggtgaa gaacttttcc taaataaaaa
      661 ggttggtaaa agagatataa gaaataaaat tcaattataa gatatggtat gataactaaa
      721 ggcactatat ggagtgaata ggcggaagaa ttttttgaaa attataaaaa tagtttctgt
      781 tgctacatat caataagtat agatagagat tgcaaaatcc atagcaaaaa tcgaatttat
      841 aagtgtaaat aacatgtaag acaaggagta aattatgagt attttagaga taaaaaacct
      901 aaataaaata tatggtaaat cggaaacaga ggtgaaagcg ttaagtcaaa taaatctaaa
      961 aataaatagt ggagaatttg ttgtgatagt aggtaaaagt ggaagtggta aaagtacttt
     1021 actacacata atggcaggac ttgaaactcc aacaaatggt gatgtgatta ttgataatat
     1081 aaatatatca tctcttgatg aaaagaaaag atctgcatta cgtaaagaaa agttgggatt
     1141 aatatttcaa tcatataatt tgattccagt tttaactgtt gaagaaaata taaaactacc
     1201 aactataaat ataaaaaata aagatgaagc ttatattaat gaattgatgg agttactagg
     1261 aataaaagat agaagaatgt atttgccaaa tcaattatca ggtgggcaac aacaaagagt
     1321 agcaatagca agggctcttg taaataaacc atcaattgta tttgctgatg aacctactgg
     1381 aaatttagac acaaagacag agtcagatgt attaagttta ttaaaagaat ctcaaaaaaa
     1441 atataatcag acaataataa tgataacaca taacatagat ataacaaaat atgctgatag
     1501 agttatagaa atagaagatg gatttataag agagtaggta gatttatgaa acttaattat
     1561 attgtaaaaa aatatataat gggaaataag aaaaatacat tattaatagt tgtaagtatt
     1621 gtaatttcaa cagcgttgtt tttaattatg aatataataa gtgaagatgc gacaaactta
     1681 atgataaatc aagctaaaaa tgaatttaca ttaaaacatg cacaatatat caatccaaaa
     1741 gacgaagaaa taaaatatat agaaaataac acaagtatag ataaagttgg aaaatcaatg
     1801 cttttaggaa ttagtgatat tggtaaaggt caaacactac aaattctatc tcaggataaa
     1861 gttgctgaag aactaaatga tatttacaca ctagaaaaag gtaaattacc agtagctgaa
     1921 aatgaaatcg ctatagattc atggtatatt aaacaaaaaa agataaaaaa ccctatagga
     1981 aaaaggataa cattagatta tagaagacaa gggatagatc aagaagattt atatactggg
     2041 gaaaaagaat ttaaaataac tggtatctta aatagtaatc ctattttaaa agctcaagga
     2101 acatcaattg gccttataag taacgattgt gctatcaaga atattcctac taaaaataaa
     2161 tatgatcaag ttatgtttac ttttaaaaag gaaaaaaata tacagagaca atcacaaaaa
     2221 cttattaaaa atggaaattt gaatgagaat aacatttatt ttaataatga attattaata
     2281 gctatatctg atagtatgaa tttaaaaata ccttatataa tagttaatat agtactagca
     2341 ctagcaacta tattattaat ttataatatt ttttatatat tagtatcaaa tagaataaag
     2401 gattttggga tatttagggc tttagggttt aatccaaatg atatttttaa aataatgatt
     2461 ttagaagtat ctatatactc tattataagt atttctatag gtctaatttt aggtgggata
     2521 atagctagtt tatcaaggga gtatgttata ggagtaatat acaatgtcaa ctatataaat
     2581 tctataaaaa accagaacta tataaacaca tacataattt ctatattatt aagtttagga
     2641 actataataa tatcagtttc aaaacctctt atgttatcag ttaaaactga tccaatgatt
     2701 tgtataagaa gaaataatga aaaagtggat ataaaacaaa attcctttat aaataaattt
     2761 atgataaaac ttttcaaaga ctatggtaac atagcatcaa aaaatataca aagaaataag
     2821 aaacgtacaa atttatctat agcatcaatg gtaattatat ttttcttaat ggcaacaata
     2881 tacacaaagt ctactagtaa ctttttaagt gatggtgtat taaaatattg gatacaagga
     2941 gattatttat tacataatat tgatataagt actatacgtt caaataataa aggttatgat
     3001 aaaaatgtac tacaagagat aaaggcaatt gatggtgtaa caaaagtaaa ctcatatagg
     3061 cataagtggt ttaatataaa aattgatgat aaaagtataa ataagaactc tgattattgg
     3121 aaaaaaaata aagataatat tgaagctaga tcagaagtaa aagatggaat caaggtatat
     3181 aataattctt ttgaattttt aggaatagaa gatacagata tactagagga tttcttgata
     3241 aatggaaagg aaaatataga taaatttagt aaacaaccat atctgtatat aacaaagaaa
     3301 tccagtgatt cgcttaatat aaaaaaagga gatagaataa aagtatactt tgatattata
     3361 gattcaaaaa caaataattt taccaaaaca atatctcaag aatttatagt atgtggaatt
     3421 ataactacat taccagtaac ctcacaagtg ggagctgaat ttggcggagt aatatcaaca
     3481 aatcaattta ataagtttac aggaatatca tcttatgaaa gatttgacat atggacgagt
     3541 aaactagcca atgataaata tgttgaaagt gagttaaaca aaataacaga aaaaacaaat
     3601 aaaggaattt taattccata caaagctgaa acagctgaat atgaaaaaat tgataatcaa
     3661 aaaacactaa ttatggtatt agtaactgga attatagtta tattatcttt atttaactgt
     3721 tgcaatacta tagttactag tattaatagc agaagtaggg aatttgcact atttagagga
     3781 ataggaatat caaaacatga aataaataaa attgttaaat tggaaagtta tatatatatt
     3841 atagtaagct tttgtatatc tataatacct attttaattg taagaagtat aataataaaa
     3901 ccttttgaaa gtatcaattt aataaattgg aaatttatag gggctattat cctaatagta
     3961 tttattttag tatctataat catgataact acactaaaaa cattgaataa aattcaaaat
     4021 gaaaatttta tggaagaaat aaagacttta tagtgaacag cctataaatt aaagaggttt
     4081 tatatgaaat taattgcaat tatcgataat ggtgtagata ttgattttaa ataatttaga
     4141 aataaaaata aaataagtta tccaagttat atgtatggtg taataggggt acaatgtata
     4201 gcaaatataa atattggctt aataaaactc tactcttaag tctactgtcg ttttaacaca
     4261 agactaataa taagtgtaac ctaaaaatta ttgataatac aataaccttg tttatgataa
     4321 ataacaaata ttaagtgttg taaagatagt aagtttaaaa aaatatcaaa gatttcaatc
     4381 acaatgtatt gtttatctgt agtgttagct atttatggta tatatgtatt tataaattgt
     4441 actgaatata tatatactat gctatctaca aaacatttaa cagtcaaagg aaatgaatat
     4501 accattataa attattatat gagtaacttt agtcagtata taatatttgc tattttactt
     4561 gcatcaatgg gatttgtaat acaaaagata gtgcatatgc atttcagtga gatagaactt
     4621 agtggtaact attcaacaac tgttagaaat ataagtgata tctctttaga taatgataat
     4681 gaaatgttta atagaggcaa tattgaaaat agtattttaa aaaaataaat aatataaata
     4741 tataaaatgt gattgaataa agcttagaat acttagtgta ttttaagctt tttttattat
     4801 taagatttca aagtattaaa ttaactatat aaaatcatat aaaaataatt ttaaaatatt
     4861 taaatcattg atttcaaggt attgtatttt taaaagagta aaaatataat aagttaggta
     4921 tataatatat ataaagtaaa aaataaaaaa atggaagtga ttgagatgag tagtatattg
     4981 ttggttgaag atgatttaag tttgatatat ggattagaat attctataca aaagaatgga
     5041 tttagtgttg atgtagcaag aacagtagaa gaagcattgc aaatttataa agaaaaaaat
     5101 tatgatttac tgcttttgga tgtatcctta cctgatggtg atggttttga tatttgtaaa
     5161 agggtaagag aagcttctaa tgtaccaatc atatttttaa ctgcttctga tgaagaagta
     5221 aatgtagtga tgggacttga tatgggtgga gatgattaca taacaaaacc ttttaaatta
     5281 aatgagttaa tttcaagaat aaaagcttta cttagacgtt ataattttac aagtgaaaat
     5341 gtaactgaac taaaatcaaa taatattact gttaaattac ttgaaaatcg tgtttttaaa
     5401 aatgaaattg agcttgagct tactacagca gaatataaat tattatgctt acttatgaaa
     5461 aataaaaata ttgtacttac aagaaaaaat atattggata agttatggga tggaaatggt
     5521 agttttgtag atgataatac tctgtcagta tatgtaagaa ggttaagaaa taagattgaa
     5581 gataatcctg aaaatccaaa aattctatta acagttagaa gaatgggtta caaatggaat
     5641 gttataaagt gagggtgtta atatgaaggt attttctaat aaagacataa aaatattttt
     5701 tttggtgatt atatccgttt tattgatgtt tatagtagta ggtcaaatag tagttataaa
     5761 tataactaat gattataaaa gtgcactgtt agaacatgat tataatatag ctggatactt
     5821 aaatagtatg ggtgttgata aatcaaaaat accagcagta tttactacta atgaagataa
     5881 atatacttta aaaggaaaag aaatcttaaa tacagctaga tatgactttg gtacagatga
     5941 tagttttatg ccaagtgtga aattgtttca aggtaaatat ataaaaacta tgtttttgta
     6001 tttatttgtg ttctttacta tgattatttt tatattgtat gtgtattttt ttaagcaaca
     6061 gaacaagata gaagaagcta gttataaaat tgattcattt atgaatggaa atataaatgt
     6121 acggttaaat acttatgaag aaggtagttt atcaaagtta tttggttcaa tagatgctat
     6181 gtcaacatct ctaaacacac atatattgaa agaaaagcag aataaagaat ttcttaaaaa
     6241 tacaatttca gatatatcac atcaactaaa aactccactt acagcattga tgatgtataa
     6301 tcaaatattg caggaagaga gtcataatag tgaaattgtt gagaattttg tgcagaagag
     6361 tcaaaatgaa ttagagcgta tagaatcatt gatacaaaac ttgttaaaga ttacaaagat
     6421 agattcaaag acaataattc ttaacaaagc tagtgttaac gtaaaaaagt tgattactaa
     6481 aattttatat agttttgaaa ctagagcaga aaaagaagga aagagtatct ctataagagg
     6541 tctagaaaat acaaacttgt tttgcgatta tgaatggata tcagaagctt taagcaacct
     6601 tataaaaaat gcattagata atacaaaaga gaacgataaa ataatgatag aatgggttga
     6661 aacacctata acaactatta tttcagtgag tgataccgga aatggaattc atattgaaga
     6721 tatacatcat atatttaaaa gattttatag gagtaagttt tcaaaaagta atcaaggcct
     6781 tggattaggg ttgccactag ttaaatctat catagaacag cacaatggaa ccataactgt
     6841 agaaagtaat tttttacaag gaagtacatt tactctaagt tttttaaagc ttactaatat
     6901 gtaagatagg atacatctta cagtaaggtg tatgaattat tcttatatta atcatcagaa
     6961 aggagataga gcaaatggat attcttgtgg ttaataattt atgtaaaaca tatggaaatg
     7021 gatatacaaa agtagaggca ttaaaagatg tatcatttac agtttcaaag ggagagtttg
     7081 ttactgtagt tggagaatct ggctcaggta agagtacatt attaaatctt ttaggaggtc
     7141 ttgatactcc aacctcagga aaaatatttg ttgatggtaa agaaatatgt tcaatgaaag
     7201 aagaaaaaca gactattttt cgacgtcgta atataggttt tatctttcaa tcatataatc
     7261 ttatacccga attaactgtg gaacaaaata taatatttcc tttactacta gattacaaaa
     7321 aaccagacac tatttatcta gatgaagtat tgacaatttt aggtcttaaa gatagaaaaa
     7381 gtcatcttcc aaatcaatta tctggtggtc agcaacaaag ggttgcaatt ggaagagcat
     7441 tgattacaaa gccatcaatt atattggcag atgagccaac aggaaatctt gacagtaaaa
     7501 atagcagtga tgtaatttca cttttaaaag tgacagcaga aaaatataac caaactatta
     7561 ttatgataac tcataataca aatatagctt ctacagcaga taggatacta caggtttctg
     7621 atggaatgct taaagaccta ggggtgaata gagaatgaga agctatttag aactagtacc
     7681 acaatatgca aaggtacata agaaaaaaaa tagaactaca attttatgta ttgtcattgc
     7741 agtatgttta gttactgcta tttttggact agcagacatg gctatacaat gtcaaaaagt
     7801 acaatttata aaagatgatg gaaattggca catagtactt aaaaatctta atgaagaagc
     7861 tatatcagaa ataagtagta gagtagatat agctcactat ggtagaggac aagtcattga
     7921 taatggagag tttaaatcaa aggagatttt gatacaaggt ttagatgaag atttagcaaa
     7981 acaattaggt ctagaaataa taaaaggtcg ttatcctgtt gtggagaatg agactttaat
     8041 agatgtagat gcagttaaaa gctttaatct aaaagtagga gattttatca aaataaaatt
     8101 agcagatggt agaaataaaa attataagat agtaggtgaa tattcatcat tatcaagctt
     8161 aagagcctca gataagcatg gattaatgct ttcaatatta ggtacacaag ctatcaaaaa
     8221 atcagaaaca tatgattatt attatattac atttaaagac aaggttaata ttagaaaagc
     8281 tacttctgat attaagaata ccttcaattt aagtgataaa caaatcggta aaaatgaaaa
     8341 attactttct attataggtc aaggtgactc tgattattct aaaccacttt acttaacagc
     8401 aggaggactt tttatacttg tgttaatagc aagtattatc atgatatata atagctttaa
     8461 tatgggtgta atagagagaa taaagttttt tggactatta cgttgcttgg gagcatcaaa
     8521 actccaagtc aaaaaatttg ttgttttaga aagtttaatt ctaagtgtaa aggctattcc
     8581 actaggattg ttattaggat gtattgtaac cattatatcc tctatatttc tcaaatatgt
     8641 gaatacagag ttatttggtt cgatgccaat tttaaaggtt agctttattg gtattgtgtt
     8701 tggaataata gtaggatttt taacagtaat attatcagct attgttccag caaaaaaagc
     8761 ttctggggtg tctccactaa gtgctatacg tggtaatcta atgttcaaag aaattttaac
     8821 tagtggaaaa gcaagtaaaa ttgctaacgc aggaagttct aaaattgatg tttctatggg
     8881 aataaatcat gccttttcaa gaaaaaaatc ttttatactt atgacttctt catttgctat
     8941 tagtattgta ttgtttttag gttttagtgt atttatagac tttatgtatc aggcacttaa
     9001 acctataaaa ccagaagctg ctcatatatc tattgttgac gctgacttta agtctgttct
     9061 tactaaagac gatattaatg aaataagtaa tatcaaagga ataaaaaaag tatacagtag
     9121 aatgatgacg gatgtagagg ctacatacaa taataaggag gcaacatctc agctaatttc
     9181 ttatgaaaaa aatcaatttg actgggccaa aaagtatcta gtaaaagggg aaatcaatga
     9241 agataaatta gagtcagaaa atatcggatt ggtagaagaa ggtcatgggt ttaatattgg
     9301 agataagata tatattaaaa atggaaattc taagaaagag atagaggtag caggtatact
     9361 ttcttcaatt tcatttgatg ttaaagacaa atatattgga aatattataa catctgaaaa
     9421 tacttttact agtataacag atataaaaga ctatataata attgatactc aagttgatga
     9481 agatgctcct gaagatttaa tccaaaatat aagaaatgtt ctagatgata atttagaggt
     9541 tcgagataag cgacaaggta acttagaggc taaaaattca ttttacacta tggcagtttt
     9601 tgtatatggg tttgtattta taattgcgat tataagtatg tttaatatca taaacagtat
     9661 gaatataagc gttacaagta gaataaatta ctatggtatt atgcgtgcaa taggcatgtc
     9721 caataagcaa ttaagaaaaa tggtaatagt agaatcaagt acatatgctg taagtggctg
     9781 tttattgggg agtgtacttg gattaatatt acatagatat atatttgtat ccttagtaac
     9841 attaaaattc catatagact ggcaaatacc ttttgattta ctgtttatca ttgtagtaac
     9901 tatgataata ataactttgc ttgcagtaag aaaacccatt aaaaagattt gtgaattaga
     9961 cataatagag gtagtaaatg cacaataaat ataagtagta atttaaatag aggtagtaat
    10021 ttaaataaaa aatcgaagta aatatgaaat agaaaatatc tttcataatt tacttcgatt
    10081 tttgtgttat ataatttact ttagataagt tccatcttca tcttgataaa ttaagtcttt
    10141 cttcataagt actccaagag cacgtttaaa attttcttac ttgaattaaa taagatagaa
    10201 atatctttag gatcagattt atcattgaat ctcatatatc catctgaacc ttctaaatag
    10261 cttaaaatct tattttctaa ggtatcaagt tcatcttttc tgtttcctct aggagaaagt
    10321 cctaatttac catcatcgta tatttttata acatgtaaat tttcaagaac atccccagct
    10381 tttaattctg taaagtattc attatgaagg attacaccag catatttatt gtcaacacat
    10441 atcatagcag agttgttggt ttggaatcca tatacaactc catttacaac atctcctaca
    10501 ttgtaagtat ggtctgtttc taaatatgaa tctatgtctg tagtagcagc tattcttccg
    10561 cttttatcca agtatatata gaataaatat ttttcatctc taaacaatgg ataagtctta
    10621 gctttaaaag gaactagtat gtcttttgta agtcccatat ctataaaagt accaatatcc
    10681 gtgttatcaa ctacttttag atacgtaaca tctccatttc taattatttc tatagtatta
    10741 gaaaaataat ttttaaatag tttgtaaaat attattgaat tttttctctc gaaatatata
    10801 atttagaatc ttctgattta tttttatgct cgatttcctt attttttttc ataaatatat
    10861 atagaggagc tattaacaac attgccccta atcctattaa aactctattt tgagttatag
    10921 gttttgaaat atcttctgcc caagcttgtt gtaacaacca taagctacct aaaatagcta
    10981 ccattggtat aacaggacca aatggaatct taaaagaggc cttaacatct gttctttttc
    11041 ttaaaactat tactgataaa caagttggta tgtactgagc aaatcttgca attacactca
    11101 ttactgcaag ttgttcaaaa cttccagtta gcacaagtgg tatacaacaa attaaagata
    11161 ttattattgc tacatatgga gcaccatatt tatttgtttt tcctataaat gcaggaagag
    11221 aaccttcttc tgctagagaa gaaccacatt taggagttac tattgatgaa cctatattta
    11281 taccaaatat agatattaat gttgctacag atatgaaaac tttaccataa ttgcctaaaa
    11341 atacacttga agcatctgca attggaatac tgttttcaaa tagtctatct ccaagtatac
    11401 ccatacagac aatttgaatt aatatataaa ttattgcaca tataaatatt gtggttatta
    11461 atgcgactgg aagatttttt ttaggatttt ccatttctcc acttgccaca ataaatgatt
    11521 caaagccggt aaatgcgtaa aatactaata taatggctgg acccatacta gagttaacta
    11581 catttcctga aggaacaata tttacaaatt ttataaagaa tattccaact attataaaaa
    11641 ctattaatgg tactaattta gctatagtta ttacattatt cattatcttt gtgcttttaa
    11701 ttccaaataa gctatttatt gaaagtagtg ttacgagtat tgcagctata taacctttgt
    11761 attcagtggc agattctggc caaaatgaac ctaaagctgt tgcaaatcct actgctagag
    11821 tagaccatga tataattcta ataacccaag acattgtacc aacttcaaat cctataaaat
    11881 ctccaaaagc ttttttggag tatagatatg ctcctccatt cttatcaaac atgcttccaa
    11941 cttctgcaaa acataaaagt attgatagaa ctaagagtgt agcaaaaatg tatataaaca
    12001 tactgttttg acctgctaga ttataaactt tacctggtag taagaatata cctgaaccta
    12061 ttatgctatt aatccctaat aatatcatac taaatagacc taatttctta gctttttcca
    12121 tattaattta tctcctattc ttttattaat tactgtacta attaaaatac aaagtattca
    12181 ttacatgcat cataacacct attggtaaac aatcttcatc tatattaaag ctagaggtat
    12241 gaagaggtga aattaagccc ttttcctcat ttttacatcc taaatggaag aatgctcctt
    12301 tacaatgttc tgtgtaaaaa gaaaagtctt caccacctaa agacgggttt ggtctcaata
    12361 taaatttttc ctctccaagt aattctttag tatttgatat aactgtatct actaattctt
    12421 tttcatttat aacagcagga tagttttcat cacttacatg taaagtccca acacaaccaa
    12481 atgcagatgc agtgtctcca acaattttag ctattttatc aatcataaag tttcttgttt
    12541 tgctatttaa ggttcttaaa gtgccttcta gttttacatc ttcacatatt acattgtgtg
    12601 catcaccacc atatatttta cctatagtca aaacagcagc attatttggt tctaagtttc
    12661 tacttattat agtttgtaat gatgtaacaa tttgtgaagc tgtaactatt gcatcaatac
    12721 cattttcagg atatgcacca tgagctcttt tacctttgat acttattttt atagtgtcta
    12781 cactagcatt taatgtatca tattttgttt cgataaatcc tgtttcgata tgtggcataa
    12841 catgaagtcc gaatatataa tcgaccttag gattttctaa acatccatct tcaactaaga
    12901 attttgctcc tccaaaacct tcttctgctg gttgaaataa gaattttaca tttacattaa
    12961 gtttatcttt tattgaatgt aaaactttac atgctccaag tagcatggtt gtatgtgcat
    13021 catggccaca agcatgcatt tttccagaat gtattgattt ataaggtatg ttgttttctt
    13081 cttcaatagg aagagcatcc atatctgctc ttatacaaat cgttttatct gcactttctt
    13141 ttaaaatata tgccataatt ccattgtgtt ttgtaaattc catataatca attccgattt
    13201 cttttaaata agaaattacc ttctgtttag taagattttc ttcaagagct aattctggaa
    13261 ttttatgtaa ttctcttctt atgtttataa gccatggttt tatagaatta caactttcta
    13321 ttacaaaatc ttttcctaat tctttggttt gatattttaa tttcaaagcc tgttgcattt
    13381 ttattcctcc aattgctttt tattgttata ggaatcattt aatagatttc taattatctc
    13441 tttagatgtt cttatatgcc ggtatagccc gtcattccgg gcttttccgg cacttttcat
    13501 atcggaagaa cctcacaaat ctttttatta cccctcatgt tttcgctctc aaaagtagta
    13561 aaagcagtag taaattctgc gtactactta tgccgccttg gtttcctcgg cgctttccgc
    13621 cgtagcctcc ggcttggcct ctgcggtggt ttttgccttg gcttgcagcc gttccatttc
    13681 ctcctgtgcg gaatggaaag tagcgtgggc gtaatagttc agcgtcatta caatgttggc
    13741 gtgtcccatg atgtactgca acgccttggg gttcatgccc gcgtttgcca ttctggtaca
    13801 gaatgtatgt cgcatggtgt gcggcgtcat cacatcgggc agcggctcct tgtggcactt
    13861 gttgtacttc ttggcaaggc acttgaacat ggcgtcatag ttgacggcgg ttttgggcag
    13921 gccgtcccgg ttcaggaaca ggaaatcctt ataaccgtca acctcaatgc ccttgccgtc
    13981 cctgcgcttc ttcaacacgc gctcaaacgc ttcataggcg gctgcgctca tgggcacttg
    14041 acggaatccg ctttctgttt ttggcgcttc gatatagtag ccatcctcgg tgcttctcaa
    14101 aagctggtgg tctacattta caaagcgttt ttcaaaattc aggtcagcgg gcgtcaggcc
    14161 gcagagttcg gaaatacgaa gcccggtttc cagcaggatc accacctcgt cataatactt
    14221 ggcatagacg gaatcgttct gcatgaagtc caaaagctcg ttttcctgtg taggggtaag
    14281 cggcaccttt ggtacggtat cgtcgttgat aacctcattg atctggaagt caaagggatt
    14341 cttgcggagg cagtcgtcct gtactgccat ataaaagatg gcctttaagg aacgcttgct
    14401 gttgcagatg gtgttgtagg caacgccctt ttcctgcata cgcaaggccc attctttcgc
    14461 gtcggacagc ttcacgctgt caatgctggc cgcgcccagc ttatcttcgg acagaagttt
    14521 catcaactgc tggcggctct tttgggttcc tttccgcaca ttcccgcgct gccgggtgta
    14581 cttttcataa agctggcaca cggtcatttt cttgccgatg gtgtctatcc cgtcgtcaag
    14641 gtctttctgt atctgcttga tcttctcgcg cagggaaaga cagggccgct ttccggcagg
    14701 tactttgtcg gtaggtacta acttccatga gtaaacaaac tgggtttctc caaaggtgtc
    14761 aatgtatttg taagcgtatc ttccatctga tcgctggctc tctccagact tcaaaaggcg
    14821 gcctttgttg tcccgtcttt tttcatctcg ttcttttctt ggcatttcgt catgctcctt
    14881 tccatgacgg aaagagcctt gacacgctta taacctatta taacacgcgc aaggcccttt
    14941 ttcactatat tgtgtcaagg gaatcaatga ttttttcaaa ctgcttccgc ttgatctgga
    15001 tgcggttgcc gtttaagatc acccagccag cggtggggtt ttcctcggca agccgacgca
    15061 gtttgttttc cccgatccga aaatatttgg acgcttcctc aatggtgagc gtgtattttt
    15121 cccaaatagg cacatcgtta ttactcataa catggccccc tttcttttca aaacaaaggt
    15181 tgtttgttgt gaaagtgggc agaaaataac ggacggctgc tggcacagct ccacgggaat
    15241 ctcacccccg cgtggttctc acgcggccct gctcgttgcc tgcgacgctt caaacgctcg
    15301 gactacgacg gcaagggcgt atcattgtcc tgtctgcgcg tcgtcgcccg caggctgcca
    15361 cacctgcttt acggcccggt aaaatcgctc cgcttacccc aatgagggaa agcctcttgg
    15421 cgcacctgcc gcccggctcg gcacagacag aatgtatccg tctgccctat gacgcgccgc
    15481 cattatcctg cgggcgtatt tgtcaaggag caaaggggcc gccgggaaac aggcaggcgg
    15541 ggaaagggaa agccgcctgt ctatggccgg ggccttaacc gtcagtcgcc aatgggacta
    15601 acgatggaat ggatcagctt gatttgcaat cggcgcttca tatactcgtc aatgcagata
    15661 tgaggctgac cgctgccgtc atagagcgtc cgggtacaca gcttattgat gtagccgtca
    15721 taatgctgca agacacgctc cacggcttcg gcgttaccgg cgcaggccgc gtcgatcaca
    15781 aaatcaggta gagggctttt gcccttgtaa ctggattgct tcatccgcgt ttaacctccc
    15841 tccggcatga acgccatcaa ttttatacgc aagtctttca gggtgcttgt cctgtggcgc
    15901 tgtactgcgc tgcgggacat tcccatcagg cggccaattt cttcgtcagt caaatccaga
    15961 acaaagcgga gaatcaaaat actctgctcg tcttttggca ggctggcaaa cgcttcggcc
    16021 acaagctcgt tgtcgatatg taggtcatag ccatgcgaac tgaatataaa gctgtcgcag
    16081 gaataccgat ctacggtcga gagcttgtcc caatcagccg gggaaagagc gtccagcgac
    16141 acttcacggt cgcggcggca cttcatttcc cgcagataat ctatcgcctc atggtacaga
    16201 accagcttgc agtagcggtc aaactggccc cattcaccgt atttgcgggg gatcgcttcc
    16261 atcttctcac cccctttcta tgggggatgt ggtggttctc tccctttccg ccaatagagc
    16321 gaatggaatc tctctggctg cccgctaaac gcctcctttt ttcacttttt tgaaatttct
    16381 ttttgcaccg gatagcagac cgcaggaaat aacaaaattc gcccggcagg tcaaagaccc
    16441 acagggcgaa acaaaaagca atatgttctt ttcttacatg gtatagtaca tactcgcagc
    16501 cgcttgtccc cgctgccggg ggacggcttt ttttgacagg ctaacccctg tcagaatttg
    16561 tcgaagcggt tttcgttgca tagcggctcc ctcctaaagc cgccatgcca gaacacggtg
    16621 caggggtcgt cgaagcaaaa agaaacggcg gccttgatct actcaaaacc gccgtatcgt
    16681 cagtgataca ggaaagcgca cgaaatcctc tgcccgtcag cggttttttt cttttccccg
    16741 ctgtggaggc agatgtttga atatgtaggc tcgtttcatt ccacaaagaa caaaacccgc
    16801 cggatcagct ccgggatatt gaccggggcg gtgatatagt cattcacgcc ctcatgccgg
    16861 tattcatatt ccgtggcaag gtcgttgttc tcggtgagga taaagaacgg cagaagccgg
    16921 acagggggat tcttcatttg gaacatcccc gccacccgcc gcagtgtatg aaacagctcc
    16981 attgctgtgc cgtccgtcag ttccacatca cacaagatca ggtctatttc cttatcctca
    17041 aaaatccggc gcttggcttc cccaatcgag ggaaccagaa tcaggtcaaa gcccttttgc
    17101 agcatagcag cccgcagcac tccggcgttg gtatcttccg catggacaaa gagcagcttg
    17161 tgaaaagtcg gggccttttc gccggataac tgccggtaag cgtattccac cagcttatct
    17221 tgcagcagca gccctttcat tttgtccatg cacagcgttg cgccccggcg catagcctcc
    17281 tgttcgtagt cgtccttgtc atggcaggac gccagaataa aaggcagctc cttgtctgcg
    17341 gcccgtacct cgtccagaaa gtccatgccg gaaccgtccg gcaggtcgag atcacagcag
    17401 actaccagcg gcatttcctc ttggatggcc gcccgcgctt ctttcagcgt gcaagccgtt
    17461 ttcaccgagt atccccggtg ctgtaagtat ttttgcagac accatgtata ggtgtcgctg
    17521 tcgtcgatca gcagtatctt tttcatgtgt cctcaccccc aatattgatt taccataagc
    17581 ataaactaca aatgttacac aaatgtccga ggtgccttcg atttcgacag aaaaacaggc
    17641 tgaattgtta caacgctcgg acatttcaaa aatttttttg agaaatggcg aaaaaggcgg
    17701 ggcagcatac gccgccccgc cgatcccata cggttattcc attacccgca tttgttcgat
    17761 cagggattgt tttttctgtc tacggattgt ccatacagac aagatcagct ccattccgaa
    17821 caacaccaga atgaacagcc ccatttccaa aaccgggaat ttgtaaggca ctacatttcc
    17881 ggcaaaagca cctacactca tttttctgca agcaaagatg gaagccggaa gcccaacgat
    17941 cagcgtcgcc aatgttgcaa agagcgcata gcacagcccc tcacagatgt tcattttaca
    18001 tagctgtttt tgtgttaggc cgatagaacg cagaatactg ttttcctgct ttcgggctat
    18061 ctggttagag agtgtcgtat tgataaggtt gataacgcca aagagaaata ccaaccatga
    18121 aagtatctcc atactgccaa acgcaaaaga atttgtcatt tcttcatatt caatcactgt
    18181 attgatttca tctaaggcaa tattactatg gctggcaaca atatttttca attcagctcc
    18241 cacatagtcc gtttttttag ggtcatttac aatgctccat gaatagtcaa aagaggtgat
    18301 ttccgggtgc agttcgtgga acaacgcttc tggtgcaaaa agagttgccc catctaagtg
    18361 catcctgcca tgtcctgaat atacctttgc aggagcgtat aaccccgata tggtaacaga
    18421 aacggatggc tgttcttctc ccaaagaaat ctcaaccgtt gaaccaacac ccatatcctc
    18481 attctgcttt agcacattat agtcaattac aatactacgg gaatctgttg gcatggttcc
    18541 ctctgtcaaa gccgcttcaa ctgccgcata attctggtcg gtcagcatat cgcacatacc
    18601 accagcttga tgaatctttg ttttataagt tgcatggaga gattgcctgc ttggaattat
    18661 atctgtaacg ccatcaatag ataagatttc ctgcttcaat tcctcattca atggatttcc
    18721 cgctgccata accttttctt ctgtcatttc agaatccaaa taaattttat agtcgccgtc
    18781 cgggaaaaac tgtcttgcaa gtgcctctgg tgagcgcagc aaaacaatgg aggataccac
    18841 aagcaggata attccgccca aactcaatga ggctacaata gcaacggtct tttttcggtc
    18901 acgcttaaaa tttgcaattc ccattgaaac aggattgagc ttgatattct ttttccggct
    18961 gcggatgtcc ttttgcgccg gggtaaaacg gacggcttca atcggggaaa tccctgccgc
    19021 aatttttacc ggcttacgga tggaaacaga taccatgatc caactgctta tgagtgtcaa
    19081 aataaccgtt gccacatagg aaacagcgtt aaaaccctta gaaaacagga gaaaaccgcc
    19141 gcatacaccc agcactgtac caatcaaaat cccgatactg ccgagtttac gcccctcccg
    19201 ctttacaatc cgcttgattt gctttggcgt tgcaccaatc gtccgaagct gcccgtagct
    19261 cttgattttg tcattgatgg agatacggaa gatactctgg atcacaatat agccgccgat
    19321 cagaacaatg gcaatcacgc tagcgatcag tgcaaaatca aaggatttag aagcataggc
    19381 aaaatactta ctgttcattt tgggcatagg aagctgatat tcctccgcaa tctccctaca
    19441 ataagaggtc atcagttctt cgtccaactg gtcgctgttt ttgaaatggg cataggcacg
    19501 atacccagcc gggtcaaacc cagcccattc tgtcagggcg gctttggaaa gaatgatagc
    19561 gcaggtattc gcttctttct catttgcgct gtccataatg ccggtaacaa cataattacc
    19621 atgaaagctc tcggtatcta aggtcacagt gtccccaatt ttggcattgt ttccataggt
    19681 ggaaagaaag tattcgctta cgacaacttc atttgctttt tcaggaaccc tcccctctaa
    19741 caactccatc tgcgccttgg taatctccat catttgcgcg tcgcaataca cataagacgc
    19801 atgatagccc tgttccgaaa gttcctcacc cagcatatag tagccgccta cgcgctcaaa
    19861 ctccggcagt cctttcaggg tttcaatgtc gttttcctcc acgcccagcc agaccgcctc
    19921 ataagtatcg acaacctgat tgcgttgcat ttgtgtcagg gaagtagaca caattcccgt
    19981 aaagcagatt agaaacgccg ccagcgcaac ggcgatcact accatcagat tccggcgctt
    20041 ctcgctttgc aaacttttct ttgccagctt ctttgtaatg ccgctggtat cattttcaaa
    20101 aggccatgtc atagcctgcc acctccttac tccacaatct tgccgtcctc aatgcggaca
    20161 atccgatctg caagacgggc aatatcgttg ttgtgggtaa tcatcacgac agtttgccgg
    20221 aactccgcac tggtacgctt gataagcccc agcacctcgg cgctggtctt gctgtcaagg
    20281 ttgccggtcg gctcgtcggc cagcacgata gccggtttgg taatcagggc gcgggcgata
    20341 gccacacgct gctgctggcc gccggaaaga ttgttcggca tatttttcag tttatcttcc
    20401 agtcccagca ggtgaacgat ctcgtccaaa aacttctgat ccaccgtgtc cccgtccagc
    20461 tccaccggca ggacgatgtt ctcatacaca ttcaggatgg gaacaaggtt atagttctgg
    20521 aagataaagc cgatgttgcg gcggcggaaa atggtaagct gttcgtcgtt catttttgac
    20581 agctctttgt cccggacaat cacattgccg gaagtagggg tgtccagccc gcccatcatg
    20641 tgaagcaggg tggacttgcc gctgccggag gttcccacaa cggccacaaa ctcgccgtca
    20701 ttcacggaga agttcacgcc gtcaagggcg cgggtgatat tcggctctgt gccgtaatac
    20761 tttttcaggt cgatagtctg taaaatgctc ataaaattca atcctttctt tgtttgttgt
    20821 aaaagcggaa cgctgctgcg ccggtggccg ccaactgtac cagaatcagc acagcgaaca
    20881 ggccgaagct ctcatagtag aacagttcat cccaaaacag aagaacatcc cagagggcag
    20941 tcaaggcaac cgtccagcgg atgtgccggg ccagccattg ccggaacacc agcacaaggg
    21001 caacgggcgg gacgatcagc agcgccagat tcaaaatcaa ggtcgaggtc agttccattg
    21061 cgtcgcctcc ttacttttgt tgataagggt attgtaaaac ccaaatgtcc gcgaaatgtt
    21121 acagcggcta aaaaatatca ttgaaaatcg ggatgaaatg ttacaacgct cggacatttc
    21181 aaaaaaattt acggcgggca gccgggaatg gccgtccgcc gtgatttctt atcgaaaaga
    21241 tcacactctt tttattctgt tcgcaatctt tctactatac tttcttttgc catactacga
    21301 tatgtgataa gcggaattgt aattgcaagc actaccaaaa ctggataagc cgtcagtaag
    21361 ggaatgagtg taaagttaaa ctggaaccat gtcaaagaat ttataatcgg ctgcatgatt
    21421 ccaaaggaaa taatgacact taaaacaagt gttccaatga ccgttcctat cacatagtat
    21481 agcccctcta aaaccaacaa caatttaagc tgctttccgc tcattcctat actttgcaac
    21541 atagaaagtt ctcgtttacg gacgataata ctcgttatca gcgagtttgc ataattgaca
    21601 acaccaataa acccaatgag caggcttaat gccattccta cgatggttaa acttttcgtc
    21661 attccggcaa attcttctgc aagctgcatt ttggattcaa attgcagttc gccggtttgt
    21721 tctccgaaac tgattaaaat gttttcaaat tgctgttcac tttcatctgt actgttaaaa
    21781 gcataggaca tgatggactg atcctgcacc gtagataaat attcatcctt tggcagataa
    21841 aaagtaattc ccgtagttgc ccggcttgtg ttggaatagt ctgcctttac ttttgccagc
    21901 aggatatatt ctttggtttc atatgcgttt gttttttcat tatagtaatt gagcttgatt
    21961 ttgtccccga cttgaaactc tgtcgctggt tcatcatcta aaattccttg gatgatataa
    22021 tcccctgtct caaatttttc aagatcaagc tcaccctcta aaactttcag gttggaactg
    22081 ataaaaggtt ctatgccata tacatctgca cgaggataac cgtctgtatg aatggaatag
    22141 ttggacgggt tggagctttg aacactgaat ccctctaacc ggttcatatc tccatcataa
    22201 ggtcttgcat aataaattcg tccgccagat tcaaacccat tttgcatttc aagtcccatc
    22261 aataattcgt cttgtattcc agcgtctttc cagtaatact gcatactaaa gtaattgcta
    22321 ttgccaacca aaaagtcact gtttaatttt ccagcgatat acttattcac atccaaactc
    22381 tgtgaaaata tgaatactgt gttaaataat acaagcccca gcaccataga taccacagaa
    22441 agaattgtcc gtttacgatt tctccataag ttcgaccatg ccatacggta tatttttcca
    22501 ccatttgtag agttcttttc ctttttcgca tttcccgata catcattaaa ccgtagcgcc
    22561 tccataggag aaacattagc cgcaactttt cccggcttat aagtgctaat ccataccgtt
    22621 attgcagaaa aaatgattgc accaataaaa ataatcggac ttgcctgatt ctctgctttt
    22681 atatcagaac taacctctaa tccggttaat accatcggag ccagtacgca accaaagaaa
    22741 taccccagaa caacaccaat cggaatcccc acaagggaca aagaagctgc ctgcttagta
    22801 atataatgct ttaactgccg tttggttgtg cccagagctt ttagctgtcc ataaaagtga
    22861 atttcctgaa tgactgaaat ttgaaaaata ttataaatca acagataccc agtaaacaca
    22921 agaaatgcaa tagcaacaac aaacgataaa agcataatcg gatcatctac aataccattg
    22981 ctttgatatg cgggacttat actggcttca actatattca ttgcttccgg gttctgtata
    23041 ttttccgacc attgatagcc gtgtcccgtt ataagactac ctaattttcc agacaaatca
    23101 aaggtattct tgaacataac atagctgctc actgttccag ctaaagaacc atcaacggca
    23161 taagtattga taagttctga agaatgagcc tgccgatatt tttcagatac aaaaattcgc
    23221 ccaatattca ataaggggtc ggattcatag tacccggaaa gaataaagtt ttcctgatat
    23281 tccttgcctt ttcggtaaaa ctccaacgaa acctttgttc caatctcatg cggcaaccct
    23341 aaagcctcta aggttttcgt gtccattaaa acttcatttt cagcaacggg aatgttcccc
    23401 tctgttggca tacagtttgc aaattttaag ccggtatcat ccatatacca cgcttcaatt
    23461 tgccgtccct ctaattctgg attgccaatt ttatctgcaa caaccatccc atagctgatt
    23521 tcttttaagg atgagtcagc tttcaattca ttgtagattg tatcatcaat atattttatt
    23581 gctgcatgac catccgatcc catagtacga atattctgcg ttctcaatgc agcagcaatg
    23641 ttggtaccaa tcgtaaaaag ggaggcaaac atcatagtgg ttaaaatgat tgctaaaact
    23701 gccgccatat ttcgcttttt atttgctttt aggctacttt ttgatagatg tttaataatt
    23761 ttcatattgt cattctcaaa aggccatgtc atagcctgcc acctccttac tccacaatct
    23821 ttccgtcctc aatgcggaca atccgatctg caagacgggc tatgtcgtca ttgtgggtaa
    23881 tcatcacaac ggtttgccgg aactctgcac tggtgcgctt gataagcccc aacacctcgg
    23941 cgctggtctt gctgtcaagg ttgccggtcg gctcgtcggc cagcacgata gccggtttgg
    24001 taatcaaggc gcgggcgata gccacacgct gctgctggcc gccagaaaga ttgttcggca
    24061 tatttttcag tttatcttcc agccccagca ggtaaacgat ctcgtccaaa aacttctgat
    24121 ccaccgtgtc cccgtccaac tccaccggca ggacgatgtt ctcatacaca ttcaagatgg
    24181 gaacaaggtt atagttctga aagataaagc cgatgttgcg gcggcgaaag atggtgagct
    24241 gctcgtcgtt cttctttgcc agttcttcgc ctcggacaat cacggttccg ctggtgggag
    24301 tgtccagccc gcccatcatg tgaagcaggg tggacttgcc gctgccggag gttcccacaa
    24361 cggccacaaa ttcgccgtca tttacagaga agttcacgcc gtcaagggcg cgggtgatgt
    24421 tcggctctgt gccgtaatac tttttcagat caatcgtctg taaaacgctc atactcaaaa
    24481 ctcctttcaa ggctttctgc ctgttgataa ggctattgta aaacccaaat gtccgcgaaa
    24541 tgttacagcg gcaaaaaaat ttcattgaaa atcggggtga aatgttacaa cgctcggaca
    24601 tttcaaaaaa atttacggcg ggcagccgga aatggccgtc cgccgaaaca tactacacga
    24661 tcttttagat agattgattg tgaaataatt tcaatccaat caccacatct atcataagtt
    24721 ccacaatgag aattatacta atggcaaaat taaaattaca taggttatat aatccgatat
    24781 agatttcaca agtaagaaat acaacttgca gacacaaatt taagtatgtc actaaatgct
    24841 cgttagttct attccacaat ctaaacagga acattgtaaa aataggtttt ccagaaaaag
    24901 caaaaagcac tgacaatatc ggcaccaaaa atatatagta agaatctact gcattgctgg
    24961 gggttgtacc tgtccattga attgctatat tatcaggaac aacgaaaaat aaaacaatag
    25021 ataaaataac attgattatt aagatgattg ttgttgcttt gcaaaaattg atttttttca
    25081 tggtgttttc tcctgttata agtgtgcttt atttagtcgg cagcataatg gaaaattccg
    25141 aacccttgcc cggctccgaa accactttga tatagccgcc ctgccgcgtt acgatctcgc
    25201 gggccagata caggccaatg cccacgccct gctgttcgtg tacttcttcc tcacgataaa
    25261 agcgccggaa gatggcggcc tgattgcttt cggaaatgcc tttgccggtg tcggtcactt
    25321 tgatctccac atacatttcc cactgcacca ccgacacagc gattttcccg cctgccgggg
    25381 tgtacttcac cgcattgtcc agcaggttaa aaagggcttc ggatgtccac ttgctgtcat
    25441 gggaaacggt caaatcctcc gggcagtcca cggacacggc aatttccttt ttctccgctg
    25501 catacacgat cccactcatg gcctgcgcca cggtatcaaa gaggcggccc ggcttcttat
    25561 ccaactggat cacgcccgtt tccagccggg aggttttcac aagagcctga aagagaaagt
    25621 ccagcttatc cgtctggctg cggattcccc ggataaagtc ggtgcgctct gcctcggtca
    25681 taggcttttc cagcagggtg tccgtcgcca ttttcagatt gcttaccggc gttttcacct
    25741 gatgggaaat atctgataca agagtctgca actcctgccg ttcctcgtcc acccggcggc
    25801 ggttctcctg catgatctgg taaagccttg ccagccgatg tccgattctg gcaagctggg
    25861 tttcgctgtc ctctgggcgc tggggcgctt cattcccggc gatcatgtgg tctaaggtct
    25921 ggcacaggtc agcggtaaac tgtgacagcc gctttccaaa cgcctgcgtc agtacaaaaa
    25981 tccccacaag ggcgcacagc agcagcgccc cgccagtcag cagcaccgca atctgttttg
    26041 tcacaagaaa cagggctatg gtgatcccgg acatggagag gacaagccct attgccaccc
    26101 gaccaaacag ccgctttacc gagaggttct taaacttcat ttcgcctcgc ctcccgtcca
    26161 ttgatacccc atgccgtaaa cggtcttgat gtagggcgcg ccgccgtcgg attcaatctt
    26221 gctgcgaatc cggctgatgg aagttgtcag ggtgtgttcg tccacaaacc tttcgtctat
    26281 atcccacagc ttttccaaaa gctgcccacg ggtcagcact cgccggggat ttttgcggaa
    26341 caggttcagc attttgtact ccatcgggga tagggtcagg ggcttgccgt ttaaggaagc
    26401 tgtctgctcc gagaagtcca gaaacagccg cccgtcgtcg taaatgtcct tggccggttt
    26461 gtggtgttcc agcatagcga acatggcttt gattttccgc tgcaaggccc cgatcacaaa
    26521 gggctttgtg atgtagtcca ccgcgcccac ctcatagccc cgtatctggt cgctttcctg
    26581 atcgttggcg gtcaggaaaa ttacgatggt gtccgggtgc tggggcttga tccgcttgca
    26641 cagctcaaaa ccgttcccgt ctggcaggtt gatgtccagc agcactaaat caaattcccg
    26701 ctggcggatg gcatcggctg cggttctggc atttagggca gaagtcacgc cgtagccgtc
    26761 tgcggtcagg ttatagtcta acatcttatt caaaaaactg tcgtcctcga caattaaaat
    26821 ctgcttcata ttctcacttc ctttgctttt tgcagatagt ataacaggca aatgtccgcg
    26881 aaatgttaca gcggacggat tttttcaaaa aagtgctttt tctttattat aggatagccc
    26941 gcttttccgt acaaggcaca aaatatgaat tataaagttt aatcttactg catatagtaa
    27001 cattccattg agaaaatatg aaatatacaa tgtagatggg tggtgctata tggcaaatat
    27061 caaagattgt cccggctttg aaactttcgg cgcagatgta aaagaggcgc ggaaagtcaa
    27121 gcagttatcg cgtaagacgc tggcggaaca ggtcaatatc gactggcgct atcttgccaa
    27181 catcgaaaat gacggcacga ttcccagcct gccggttatc atacagctta tcaaaatctg
    27241 cgggcttccc gtggaacggt attttaaccc ggagatcatg cgggaggaaa gcgcacagcg
    27301 gcagcgggtc agccacaagc tgaaactctg cccggaagaa tttctgccga tcatcgaggg
    27361 cgcgattgac ggggccattc aaattcaaca gaagaatgac gaaacggagg gtgcatgata
    27421 accatctgtt ttgtttttgg gaggacgcaa gctgcgccct ctcttttttt gtgcggtttt
    27481 cggaaaaacc gggattttgc gggtatttcc ttgggggcag aacgcttttt aggggaagaa
    27541 gaacaaagac agcaagcata gggagtgtag ccacactccc ggcaaacggc ttcccgtttg
    27601 tatcttgggg aagtccccaa aaccctgaat gaatggaggt gcgaaagtgg caaaccgaaa
    27661 acggaagttt gtgctgcgcg tcccggtgac gccggaggaa cgggcgctga tccaacagaa
    27721 gatggcccag cttggcacaa agaacttttc tgcctacgcc cggaaaatgc tgatcgacgg
    27781 ctatatcgtc catatcgaca ctggccctgt ccgggcgcag accgcagagc tgcaaaagat
    27841 cggcgtcaac atcaaccaga ttacaaggcg tatcaacagt accgggactg tgtacgcgca
    27901 ggacttggag gacatcaagg gggcgctggc acagatatgg cagttacaaa gatccatcct
    27961 atcaagtcaa cgctgaaaaa ggcgctggac tacatcgaga acccggacaa gaccgatgaa
    28021 aagctgttcg tttcttccta tggctgttcc tatgaaacgg cggatattga atttcaaatg
    28081 ctgttagatc aggcgtacca aaagggcaac aatctggccc accacctgat acaagccttt
    28141 gaaccggggg aaaccacggc ggaacaggcc catgagatcg ggcggcagct tgccgatgaa
    28201 gtgctgcaag gcaaataccc ctatgtgatt accacccaca tcgacaaggg ccatctgcat
    28261 aaccacatca ttttctgcgc cgtggatatg gcgaaccagc gcaagtacat ttccaaccgc
    28321 cagagctatg cctttatccg gcgcaccagc gaccggctgt gcaaggaaca cggcctgtct
    28381 gtggtaaagc ccggcaagga caaaggcaag acctacgccg agtgggacgc acagaaaaag
    28441 ggtaagagct ggaaagcaaa actgaaaatc gccatcgacg cggccatccc gcaggccaaa
    28501 gactttgata gttttctgcg gctcatggag gcgcagggct atgaagtcaa acagggcaag
    28561 tttatttcat tccgcgcccc cggacaggaa cgcttcaccc gctgcaagac cttgggggag
    28621 gattacaccg aggaacggat cacccagcgg atcaagggca ttgccatcga ccgggggccg
    28681 cacagaagaa gcaccaggga aatctccctg cggatcgcct tggaggacag tatcaaggcc
    28741 cagcagtcgg tgggctatgc gcgatgggcg aagctgcaca acttgaagca ggccgccaat
    28801 tccttaaact tcattacaga acaccagatc gacagctacg agggcttgga aagcaggctg
    28861 gccgagatca gcgcggcaaa cgacgcggcg gcctccgccc tgaaagacgc agaacgccgc
    28921 cttggggata tggtgctgct gataaaaaac ctctccacct acaagcagct ccggcctgtg
    28981 gcgctggaac tgcgaaacgc caaagacatg gccgcgttcc ggcggcagca tgaaagccaa
    29041 ctgatcttgt atgaggcggc agcaaaggcg ctcaaagagg ccggggtcac aaagctcccc
    29101 aacctgtacg ccctcaaaac cgagtataaa aagctggacg cagaacggga acggctgtcc
    29161 gcacagtata gcgaagcgaa acagaaattg aaagaatacg gcattgtcaa acagaatgta
    29221 gacagcattt tgcggacagc gccggaaaag gagcatacgc aggaacgatg aacataccga
    29281 gaataagtta cccccaatac cgcaaggccc gcaggctcac ccatgagtgc tgcaactact
    29341 gtaacggaaa ctgcctcctg ctggacgatg gggaggaatg tgtctgtgtg cagagtattt
    29401 cctattcgct gctgtgccgg tggttcaagg tggccgtcct gccgctggac gcggccctgt
    29461 gcgccgagat caccaaaggc cgggacgaga tcaaacgctg cgccgtttgc ggggcggcgt
    29521 ttacgcccaa ctccaaccgg gccaaatact gccctgattg cgcggtgcag gtacgccgga
    29581 aaaaagaggc ggaacgccaa cggaaaagat acctcctgtc tacgcattta gggcggtaaa
    29641 agtccacgga aatcaagggt ttttccgcat agtcggcagg taggtggata aaattatcct
    29701 gttcccctca aaacagggtt ctaaatgcgg gaaaatagac aaaaaagaag cgccggacgc
    29761 agaggcttta acacctccgc gcccggcgtt ttggataatt gccgattatg taatagcatg
    29821 atataataca gtaaaacaca gcgggaaacg gtggaacttg tatgaatatt gaaaactata
    29881 ttgaatcaca gtacagagaa ttattgtcat gtagtcaaat aaatgcggaa tactccgatt
    29941 tatataaatc atttagaaac caaaaacttc gagaaatact tatgacctta catcatgatc
    30001 tggttgggct ttttaaaaca atgaacgaaa gactaccaac cggggaacat gaagcgcact
    30061 tttgggcaga accgagtaga gatttgatta agagaattga aattatattc agcttagtaa
    30121 gttcactaaa ggaaactcct ttagcctttc aaatagaccc atactattta gatttactca
    30181 cgcgctgtcg agattttctt agttcaagcg gcggaagttc attgccgccc aatatggcaa
    30241 aggtcgaatt atattatagg cttcctattt ttctacctct tagtagcata accatttcac
    30301 ataagcaaca agattttaca tttgatttga aactgatcgg aagcggctct tatgctaatg
    30361 tttataaata taaggacact ttttataatc ggccttttat tttgaagcgt gcaaaaaagg
    30421 aacttacaga taaagaagtc gcccgtttca aaagagaatt tgatgtaatg aataatctat
    30481 cttctccata catacttgaa gtttactgct acaatcccga taaaaatgag tatattatgg
    30541 aatatatgga ttatacactg gacggatata tcgctgctca taactccacc ttaacaatta
    30601 tacagcgaaa aggaatcgcc caacaaatat tacgcgcttt tgattatctt cattcaaaag
    30661 gacatctaca tcgtgatata agccctaaaa atattttgat aaaagagtac gacgataccc
    30721 ttgtagttaa actttcggat tttggacttg taaaaattct tgatagtacg ctaacaacgg
    30781 ttaatacgga gttcaagggt tattttaatg atcctgcact ggttgtcgag gggtttaaca
    30841 cttatggcat agttcacgaa acttatgctc tcaccagagt tatttatttt gtgatgacag
    30901 gtaaaactaa tacagaaaaa attgcgaatc agaatttacg agcttttgtc gagagaggat
    30961 tgaacccaga taaaaccaaa agatttcaaa atattcgcga tatgatttca gcatttaaga
    31021 ccatataaaa atgccggacg cagaggcttt gacacctccg cgcccggcgt tttacttatt
    31081 cgtctgtgaa gtggaaccgc tgcgccgcaa agtcggcgtc actcatggcg gccagcttat
    31141 cggcggtctg gcaggccagc gccgccattt ccttgtccat gtccggcaaa actgcccgga
    31201 gatttgccgc cgtcctgcgg tggtcggcgt tgtggtacag acagatcagg ttttcttctt
    31261 ccacggtgaa atacattcct catacctcca tttcttttga tttttcccgc gccgggggcc
    31321 tctttttctg ttcctccttg gcggcggcaa gctgcgcccg gatggacggt ttcttttgtt
    31381 tctgcgtcgt cctgcgggtc tgcttgggct ttttggcctc cgccttggct gcctcggcca
    31441 catccaaaag ggaaatctgt tccccagctt ttgcccttgc ttccagttcc tccatagacg
    31501 gggcgttgtt catcatgccg tcgatcatgt tgtaattctg ctcggtggac atttctgccg
    31561 tcttgatatg gctttcctgc tgggcgggga tggcaaaggc ccttgtgccg tttgccataa
    31621 taagatactt gccgtcctcc gactggtggt ggaatccata cccggcggcc tccatctgtt
    31681 cccggctcct gtcggtcaga tagaaacggc ctctcggcgt ctggatttgt tcgccggtca
    31741 tgcactcgtc tggcgtgagc tgcttttccg gctgggcgaa aaactccggc acctgccggt
    31801 agtcggctcc ctcgtccaca tagtaggcag tctgtttccc atcctgccgg aacaccacaa
    31861 tatcccccgt agaaagggaa tgtcccttgt aatcggcggg atgttctatg ttgaagcggc
    31921 ggtaaatctc gtccagtgtg gtgtccttgt ccagcggcgc ggtgtagaca agctggtaat
    31981 tcttcctgtc caccgaaagc ccgtccgcct gcaagtcctc ataggaacgg tagcggaagt
    32041 cgcgcccctc cgggccgggc ggcacttggt agatggaaaa gttgggctgc gccggtgctt
    32101 tataatcaga ggcaacatat tcctccaccg tcagcccggc agcggcggcc tcctgttcca
    32161 gctctgcctc gatctgtttt ttgtatgcct gcaagctctg gtcgaagtcg gcaagctgcg
    32221 gcggctccgg caagtggtac tggccctgat tgagaagcgg gcggcactcc tttacatagt
    32281 ccaaaaccgc gttgaaataa gcggtctgtt ccggcgtcag ggtttccccg gatcgcaggg
    32341 gacgccgggc ctcctgctcc atagcggcca gattgcaatg cagctccata tacgggacaa
    32401 actcatgcag cagcatatcc cgctgggcct tgtccgcctc ccatgcctcc ggcccctcat
    32461 ggtgcagcac atggtttttc cagctttcat cctgtgcgta gtattcgtga tagccccgga
    32521 tatgctggat cagggaaccg tccccgtcgc caaagtcctg ccgtccctcg tagctgtccg
    32581 gctggccctg catggtaaaa tcaatgcgga acttggtctt gtcgtaccaa tggcccgtat
    32641 agcccggctg ctcctgttca tggcgtctgg cactgtccag ctccttgaaa acggcctcgg
    32701 cttcatgcag cggcatttgc tggccgtctt tcagatgggg gctttcactc caaaggatcg
    32761 tgacaaccgg ctccgctgcc ggattctgcg cgatctgccg ctgggcgttg gcaacggcaa
    32821 tctcactttc gatctcgctt ttcacaaagg aatccatctg gcccttttgc agctcatagc
    32881 cctgttcaca caggcggttg ataagcccga tcaccttgtc gttatcgccc acggcctcgg
    32941 cataggccac gatcaactgc cgttcctcgc tgcccaaacg cggggcgttt ttctctgcca
    33001 gctcgatcag ggcggcggcc cggtcagccg gggacgcctc cggcatgaac ggtttcccat
    33061 tcaaaaggcc gtcgatcccg ttccatgcct gcggctgggg aatggcgttg gcctgttcgg
    33121 ttgcttccag aaaatcatcc agcctgtcgc cggtcagggg ttccatcgtc ccagccggta
    33181 gctcatggat ggcaaggatt tcttttccgg cttccgcaag ggacaggccg ggattatcaa
    33241 gctggcctcc gtccagttcc ttgtagtcgg ggccgtacag cgtgtagtca tagccggttt
    33301 ccgatgtctg gatatacagg taatcgccgc tttccagacg gtaggcggcc tcctgcgggg
    33361 ctttggcctg ttccagcgtt ccatccccgg caatggtaaa gccctgcgcc tgcgccgcct
    33421 ccttggttcc ctgcgacact tcgccggtgg atttcaaatc cgcgtcaatg agggtttgca
    33481 gcatggcttt tacgctgtcg gtcatttcct gctgttgctc cgggggcagc ttagaaaata
    33541 cactgtccgg gtctgactgc tcggcggcct gttccagcgg cgcggcctgc ggctgctcct
    33601 gctgggcctg ccgttctttc tgaagctggg caagatggcc gtcaatggtg gtaatcagtt
    33661 catgggcggt ggcccggatg gtttcaaggg aggctttcag ctctttcaag tccttgccgg
    33721 aactccaacc ggccacatag ccaaaggaat agtcggaggt gtccagcccg tagtgctggc
    33781 agacggcata ggccacactt tcggcctgca cctcgcgggt gcggctgtcg gggcggtcgg
    33841 cctgctctat ggccggggct tccgggtcga tggcgtggag cttggaatgg gcgatctcat
    33901 ggatggccgt ctttagggtc tgtaattcgc tcatgccctc ctgaatggcg atccgctttt
    33961 ccgtcaggtg gtagtagccg tgggaaccgc ccggaatgtc ctcaaaacca atgggaaccg
    34021 gggaggtctg ttccagcgcc ttgaaaaatt ccccgtagcg ttccacgctg ccggtcagtt
    34081 cttccacgcc gatagagggc agcggttccc cctcggtctg gctcacatca aagacggaaa
    34141 cgatcttaaa ggccggaacc tgtatttcct gtacttcggt aacaggcttt ccgtcctttc
    34201 ccatcaccgg cctgccctgt gcgtccagct tttgcacttc cttttttgcc ttgaacgggg
    34261 ccggggccag tatcttgatg gccttttcgc ctttctttac attacggtga aaatcgtccc
    34321 gccacttgtt gtagcccgcc acaagctgtc cgccctgcat ggcgatcagg agggtgttgt
    34381 tgaagctgta actgtggaac ttcgccatag aggtgagata ggctttgtag cgttcactct
    34441 cgaaaagctc ctgtatgccg gtttccagcc ggtcggtgat ctctttcatg cgctcggcgc
    34501 tgttctggcc gtttaagaga atgggggtga caggctgcgg ggcctttgta ggcgctgccg
    34561 cctccggctg taccttgctt tcctcccgca gaatttccgg cgcaggatag gccatcaccc
    34621 ggtattgttc cggcaccggc tggccctcat ggacgcgctg ccattcgtcg ctggttcgca
    34681 ggatatagcc gtaatcggta aaggttccct gttcctcgct ggcgataaag ctccccagcc
    34741 gttccgtgtc aatggccggt ttccacgggt cgggaacgac aaacagcccg gaatcattca
    34801 gataatattc ccccagactg cggctgtcct tggcgttgat taagacaaaa caatcggtgt
    34861 tttcagcgta gtctaaaagc tgcccgatgg tttgcatttt tgccggggac tgcatggcgg
    34921 cgttcagctc cgccagctcc acggcgtcca gcctttgaag ctggacggca aggaagttca
    34981 gttcgtccac gctggcggcc tttatcaaat cctccggcag ttccagcggt tttccctccg
    35041 gggcagaaaa gccgccaatg aacaagtcct gctggttgtc ggcggtgatg tggatttcct
    35101 ttagggcttc ctgtacctgt tcggcggtag tcggcaggga aagccagtag ccatgcggcc
    35161 cgccggtctg cgcctcggcg cggttatcaa gaaaaataga aaatacttcg ttcacgggtt
    35221 ccctcctttc cggggtggct acggtctgct gcggctgtgc ggtttcttcc tgcgcgggaa
    35281 gctctgcggc ttttgccggt tcctccccct caatggtgta gccggggagc aggcagccgt
    35341 tgaccttaaa gcagtcggcg tattccttgg ggatggccgg ggaaatttcg gtaaagtaat
    35401 ggtcgtgggc tttgatccgg ccattcaggt acttgtccag ttcttcccgg ctggaaaaga
    35461 cttttcgttc ctgtccggtg atcttttccg tcgggttgcc gtggggtgcg ttggtataaa
    35521 ggccccagcg gagcgtccac gagtagggaa cggatttttg ggcggcgctg tcataccggg
    35581 tattctcgga aatggaataa tccatctggt aaaccatgtt gctgcggata tggcggtatt
    35641 cgtccgggac ctcccactgg tttgcagtgt gggtgacggg aagcgtccgg gcatattcaa
    35701 gggctttgtc cagaagcagg gttcttccgg cctgttcctc ccatgcggcg gcctgttctt
    35761 tcaggcggtc aaacacttcc tgttctgcgg cggcgctttc cgcccgcagg gaaagaagct
    35821 ccgcaagggg cagctttacc gcttcggaaa gatcggcctt gccgctttca aagtaaatcc
    35881 ggcgctcgat ccgcatggtg ctggccggtt ctaaatcgtc gtggtcgtag gagctgtaag
    35941 acattttggg ttcacatcct ttctgaaaaa tggcataaga aaagcaggaa acctttgaaa
    36001 aatttcctgc tgggtgggcc gataataagc ggctgatatt caattttgaa agtttgggtt
    36061 agattgattg aagctgggga cagtctaaca aattaaagct ttctacttct tcaacatcaa
    36121 taactttgat gcctcgttct tttaatgcct ttgcaaacaa tcccattcca gaaatcaatt
    36181 ttccggtaaa gctaccatca tatatttgat ttactccgca ggtaggactt ctggattgta
    36241 gtatagctaa ctcaatatct tcatgttgaa ttttggataa tgccattgat actgctcgtt
    36301 tatattccaa atcaacatca tttccatttt cgtctgttac tacaccattc acaatctctg
    36361 cacaaggtct gggagtagcc atacctgcta attgctctgg acaaatgcaa ataatttctt
    36421 tatcttttaa gtagttgata gctgccagat ttttgttatt ttttccattg tatttacaat
    36481 ccactcccat aatacaagca ctaactaata ttttcacact tatcacctca aatggatatt
    36541 atcgttggct ttattatact atgacatggt gtatcttgga atagatgaat tgtaaatttg
    36601 ctggatacaa ggggtttggg gcttccccaa agagaaaatc cccggcccgg caggtgcgcc
    36661 gggtcaggga ttttgccggg agtgtggcta cactccctat gcttgctgtt tttagttctt
    36721 gcccctctgt tccacgcggt agttcacata cttgccgcca gtatcagcca aaagcaccgt
    36781 cccgtcatag gttttgccgg ttttcatgga gcgcaggccc tttacctttg cttttccgtc
    36841 tttaaggagc gcggcggcga tcttcggggt gaacgccttg ccccgttcct caaaaaatcg
    36901 gtcattcttc cacatgacaa actggcagct tcggtttccg cagtagtagt tctttttgcc
    36961 ctcgtagacg ctttcctcgc agcgcggaca tttgccgata accacacgct cggtttgaaa
    37021 caacttctgc gcgtcctcgc tgatctggga gtagtttgca attaggcccc ttgtcatttc
    37081 tgcaatgcca gccatgaagc cctccgggtc ggcctgtccc ttggcaatgg ccgtcagctc
    37141 cgtttcccac tgtgccgtaa gctggggaga ggtcagcacc tccggcagca cgtaggcaag
    37201 gttgtggccg tccttggtgg gaagtagctg tttgcccctg cgctctacaa agcccatctg
    37261 caccagcttt tctaagatgg aggcgcgggt ggccggggtt cccaatccct gccgctcggc
    37321 gtcctccggc agatcgtccg caccggcgcg ctccatagcg gaaagcaggg tatcttccgt
    37381 gtaggatttt ggcggtgcgg tgaaatgctc ggtgacggcg gcagttacct tgtcaaaggt
    37441 ctgtccctcg gtaatttggg gaagttcccg cgcaggctcc ggggcggtgt cgtcggcgtc
    37501 tgttttgaac gacgccttaa agcggcggtc aagctctttc cagccggggg tcaggatggt
    37561 ctttcccttg gcggtaaagg tgttcccggc acaggtgaat gtagcggtga cagcttcgta
    37621 cacatggggc gcggccacgg cgcacagcag cttgcagcac acaagggaca gcagtttctt
    37681 ttccccctcg gtcagcccgt caaagcctct ctgcacaaat tccattgtcg ggacaatggc
    37741 gtggtggtcg ctcacctttt tgctgttcag cactcggcca aactgcgggg acaggtcaag
    37801 ccccgccgca aagggaagca taggccacag gccggacaca aggctttccg ccgttggcag
    37861 catatcatcg gtcaaatact ggctgtcagt gcggggatag gtcagcagct tcttttcata
    37921 aagctgctgg gcatagtcaa gggtctgctt ggcggtaaat ccaaacaggc ggtttgcctc
    37981 ccgctgcaag gtggtgaggt catagaggca gggcggctgc tccgtctttt tctcccgtgt
    38041 taccgacaca caaacggtct gcgccgtttc acaggcggct ttcagggcct tggcgtcgtc
    38101 tgcgtttccc atgcgttcac tggccgcctc catgccgccc gccgcgatct ggacgatgtg
    38161 gtatttctct ttctggaagc tgctgatctt ggcctcccgg tcaaccagca ttttgagggt
    38221 cggcgtctgg acacggccca cggtcagggt cttgtggtag aggatagaga acagccgggt
    38281 cgcgttgatc cccaccagcc aatccgcctg cgcccggcaa agggccgact gatacaggtt
    38341 atcataatcg gttcccggtt tcagatgggc gaagccgtct tgaatggccg cgtcctccat
    38401 gctggaaatc caaaggcgct gaaacggttt cttgcagccc gccatctggt agacgaaacg
    38461 gaaaatcaat tccccctcgc gcccggcgtc ggtggcgcac acaaggccgg tgacatcggg
    38521 gcgctccatc aaagaacgca gggtgtcaaa ctgctttttc ttatcgtcgg gaatgatgta
    38581 ctgccattcc tgcggcagaa tcggcaggtc gtcatatcgc cattttttga aacgctcgtc
    38641 ataagttccg gcgtcggcaa gggaaacaag gtggccgata caccagctca ccagatagcc
    38701 gttcccctcc atgtagccgt cctgtttctt gtccgcgccg atcacgcccg caatgctgcg
    38761 ggctacgctt ggtttctctg caattactaa ctgatagctc atacttcgtc ctccttattt
    38821 ccatcttcac ttgtcatatc ctcgtccggc tccggggctt cgtcctcgtc gtcctcgtcc
    38881 tcgccaaagt catactcggc cagatcgtca ttgcctgtgg tgtcggcttt ttcctttttg
    38941 aatttcagga agtagagggc tgcgccgccg cccagcagca ccaccacaaa gaacaccaca
    39001 aggccgccca tgccgcttgg cttttcctcc tgcggctgtt cttcctccgg ctggggcttc
    39061 ggctccggct cgttgcaggc ggtcaggttg tttttacaga ccgggcaggc cgtattgacg
    39121 gccccagctt gacatttggc cgtacaggtg cagacctccg gctctttttt tccatcctcc
    39181 aacaaggctt gcaggtcggc gtcgtccact tggttgagga aatgcaccgc tgtttccttg
    39241 tcctcgttgg cccggtcgat caggatgtaa aaataattcc cggccttggt agtgacagtg
    39301 ataagctgtt tatccccgaa aaaatcatcc accagcgcag cgttgccctg cggggtaaca
    39361 ggtacgccct ccggctccat gccgccggtg gtgggttctt cggtttcctc cggcacctct
    39421 gcgggggctt cggtggtttc cggcagcggc acagggtcag ggtcagcgcc tccggcatag
    39481 gcggtaacgg tcgtggtcgc catgcagagc gcagcagcca cagccagcgt caaggtgcgg
    39541 aacagtttag atttcttcat gggcgctgtc ctcctgttca aagtccggga tcggggccgg
    39601 ggccgcctgc aatgcgccgc cgcgcacaaa ggcggcgaac tcctgcgggg tcatgttgag
    39661 gccgcgcaca agctggacga tctgcaagtt ttcctgttcg gtcttggccg cttccagctc
    39721 ccgaagctgc ttttgcagct ccgcgatctt gcccttggtt ttctcaatat ccttttcaat
    39781 gcgttccaat ttgttcattg ccatagtgat ttactccttt ctggcgttta aggcaaacgc
    39841 ccgtaacaat aaaaatgctg ctgccagtag cttgaattga ggttcgtgta agaaatgggg
    39901 tcgccgcagt gcagcatgac cgaatttccc acatacagcc ccacatggga catcccggca
    39961 gtgtcataag taccgacgaa aaatacaagg tcgccgggct tggcatgctc cggggaaacg
    40021 ggagtgcaga tgttgtaaag cccctgagcc gtctggcgtc ccacattcca gccggaatga
    40081 ttgataaccc agctaatgaa gccggaacaa tcaaagctgg tgcttgggga gctgccgccc
    40141 cacacatagg gatagcccac atacttttcc gcctccgcga tcatggcggc aaaggcttcg
    40201 tcctttagcg cctccggggg gatttcatag taggttggct ctttcggggt ggaggcgtgg
    40261 ggatagctgc cgttggggaa caggtctggc cggttgccca aagtctgcat ataggcagca
    40321 taaaagccca tctgttcctt ggtgagaatg tagatgggca ggtgggacag gtcgaagttt
    40381 tccagcttca cattgcagat gtagtaggtg taggggactt ccgcggtgta ggtgtttccc
    40441 tcgctgtccg tcctcgtttc agtgcggtag cgggtttccg tttcgatggt ctgggtcagg
    40501 atgtactgct tttcaaagag catggcaagg tcgccctgta cctcccccaa agtgaacacg
    40561 ccgttatgca gcgcggagag gatggaggtc agcacatagg ggtcatgctt gatctcgtcc
    40621 agatcgaaac ggtattcgtc atagccgggg tgcaggcttt cgtagttgtc aagttcgtgc
    40681 tgcaagtctg cttccagcgc ggcataggca gcttcggctc ccagcatatc gctgtcctcg
    40741 gagagatagg aggtggcggc aagtcccgtc ccggtgctgc caaacatggc ggtgcaggat
    40801 tgcaggccgc ccatcaccag caggagcatg aggcccacgc cgccgacgat cagcgcccct
    40861 ttccagtgcc gggcggcaaa ggacgcggcc tgtctgcttt tctctgcggc tttcttggct
    40921 gcggcagccg tggtcttggc ggtgcttgcc gccccctgtg cggtctggcc cgccgccctt
    40981 gctgccttgg catattcccg cttaatgtgc tgtttctgcc agaagcggga aacgggattt
    41041 ttggccgcct gcgccagctc cgggttgtcc cgcagggatt tttgatacgc aaactcggcg
    41101 ttggcggcaa tggactttcg ctcggccttg gctgcggccc ggtagggttt gagcttatgg
    41161 cggtggacgc cgctgcggat catgcggctc gcctgccgtt ccgccagttc ctcccccttg
    41221 tggccgccct ccacgcccac attttcgtgt tctacctcat ggatttttcc gtggaggtaa
    41281 agcccggctt cctgtatggg gcggctggcc gggtttggtt tgagctgggg aggggctttc
    41341 tccaccttgt caaaatacag cctgcttttg gccttgccct tggcttcgtc atagacggtt
    41401 tccttggtga cgacgcgctt tttcggcagg gcttctttgg ccgcttccag cttatccgcc
    41461 cgcttttccg cttttttgat atacggggca agctccgggg aagcccgttc ctcggcggta
    41521 aactgcaacc gggaaacagg gctggtggcc tgcgccacgg tttccccggc gtccttggcc
    41581 gctttctttg ccttgtggcg gtcgtgcagt tcatccgccc gttccagtat tttttccgcc
    41641 gcgccctctg gctgggcggt gtattcctgc tcggcctccc ggctggacac attgacgctt
    41701 tcgccggtgg tctggttatc cagcgtcagg ccgtcgcggg tcatgtgctg cgttaccttg
    41761 tcgcggggtt ttaagggttc catgacttca cctccttgtg cctcataccg tcgccccctc
    41821 gcctaaccgg gtcgtcatga tctggtagag ctgggtgttt ttcgggatgg ggttcttaaa
    41881 gggcaggatc acattttcgt aaatgagaag cccctcgccg ggttcggaat tgtccacata
    41941 ccgtaattgc tggggcgaaa tgttcagccg ttccgcaagg attttgcggt cgccgctggc
    42001 ctgattgagc aggcagataa agtcgctgtt ttccaaaatg ttctcaattt ccggggagga
    42061 aagcagatct ttcacattct gtgtcgcacc tgtgggaatc ccgccccact tacgaaaacg
    42121 cttccaaatc tcacaggaaa aggccgccgt ctgttcctca cgcaaaagca ggtggaactc
    42181 atcacagaaa taccatgtcg ccttgccctt gctgcggttt tgggtgacgc gcccccaaat
    42241 ctggtcttgg acaatgagca taccgatttt ctttagctgc ttgcccagct ccttgatgtc
    42301 aaaggccaca atgcggtttt gaatgtcgat gttggttctg tggttgaaca catttaggct
    42361 gccggacaca tacaggtcaa gggcctgcgc cacccggtcg gcctccggga tatgctggtc
    42421 taaaagggct ttgtgcaggt ctgcaaggat gggcatattt tccggcttgg ggtctgccag
    42481 ataaggccgg tagatcacct gtaccgcccg gtcgatcacc gtcttttcaa tggcttccag
    42541 cccgttcttg ccgcccatga caagctcaca gaacgacagc acaaagtcgg atttcaaggc
    42601 cagcgggttt tcatcctcgg agtagttcag gttgatgtcc agcgggttca catagttttt
    42661 gctggtaggc gacagcttca ccacctgccc acgcaaccgc ttcacaaggg ggtaatactc
    42721 ggcctctgga tcacagatat acacatcgtc cggggtgcag aggaacacgc tcaaaatttc
    42781 tgatttacag ctcatacttt tgccgcttcc cggtgtcccc agctttagcc cgttgggaca
    42841 cctcgcccgt ttgcggtcga gcataatcat gttgccggtc ttggcgttga tcccgtaata
    42901 catggcgtcg ccgccctgaa aaagctcctg cgtcacaaaa gggacgaaca cggccacgct
    42961 ggaagtcgtc agggagcgtt caatctggat gtggctggcc cccagcggca ggctgctcat
    43021 aagcccctgt tcctgctggt agtccagccg cacaagggaa cagttgtatt tctgggcgat
    43081 cccggcagcc cagaacacat cgttttccag cttttgccgg gtgtctgcgg tgttcagcac
    43141 caaaaaggta agctggaaca tccgttcatt ccggctctgc aaggtcttta gcagctcctt
    43201 ggcgtcctgc ccgtaggtgg caaggtcgct gggaagtata tccatgtcgt agccgctgcg
    43261 gacagcccgt ttctgttcct gaatcttcat ggcgtcaagg tcggtgatct tgcgcttgac
    43321 cgtcttaata gcgtcgctct ggtcaatggc ctgcacatgg aggttcacca caataccgtt
    43381 ttccgtgttg aggaagtcgg ccagcatttc atccgacagc tccggggaga ggatttgcag
    43441 aaagctcacc gccccgtatt tgccgcccag cccgaacatc cgggcattgc cgaagcggaa
    43501 cgaggacggg gcgataaagt ccttggtaga aagccccgat ggagcaagcc acttccagtc
    43561 aaaggagaac ggttccccgt ccgggtggaa aatgctgtgc atgacttcca gccgttcctt
    43621 tgcgtccagt ccccacgcgg aggcccccat gctcttgaaa tagcccaaaa gatcggtttc
    43681 gatccggcgc agtctggcgc gggccatttt caggctgtct gcctcgatgg tataggtcat
    43741 aaatttccgc ttcatcaggc cgttgttccc gttcacaagc tggttttgca aaatgtcgga
    43801 atactcgctg cggatgtcgt caaagtcgtc cccctgcgcc cggatttcaa agctcttggc
    43861 gtactgcttg gggtcgatct tgcggttgat aaaggaaaac tgcacatgaa tggaagcgtc
    43921 cagatagttg tagaggtcgc acaggttttc aaagatggct gtcttggtgt ccgcctgcgc
    43981 cagttggtag ctgatgtccg taaactcaat gcacttggaa aaggtgcggg gcgttacccg
    44041 gcatacgccg tcctgataca tggcctcata gggaatactg gcctgcgccg aatggggctt
    44101 gccgtcgcct ttatactttc ggatgacggc ctgaatctct ttcttttcgg cgcgggtcag
    44161 cttgaccggc gcttttgcgc tcgtttcgtt cttttgcttt ttggacaatg gcgttgacct
    44221 ccttttccat ttgggattgc cgcacaaggg cggtataagc gttattggtc tggtagggcc
    44281 gttccttggg ctggatgaag cagcacgcta cgatctggcg taccaccact tcaaggggct
    44341 ggccgtgttt ttcgtaaagc gccagcagaa agcccggcag catggcgaac accataatga
    44401 gcgccgccgc gctggtcggg acgcggcccc ggatcaaaaa gaaaagcggg acgcctacca
    44461 gcagcgcacc gccaaaacaa atgagctggc gtttcgttag cccgaatact accttggatt
    44521 tgaccttggt taaatccttg gggacagtta cataagccat aaaaagtcac ctcgtttctt
    44581 tagtgggcgg taaatacggc cttgctgata cttcccgtct tgaacagaca gaagcaaagc
    44641 aaaacggtat agcccataca gccccagatt gcgccggata tgtcgtcagc ggttccgatc
    44701 tgctggatca gcaccgcata aatcccgaca accaccatga ttaaaaaggc ttggaagccc
    44761 agcgcaagca gggatttcaa gtagttctgg cccatgccgc gccactctgc attgcccagc
    44821 gtggcaaggg ggatcggccc caatgcggtc acggcgtaaa tttcaatcat tcttccatag
    44881 gtcacaagga aaatgcagat ggaaagaatg ttcatcgtca gccctacaac aagggtctgg
    44941 aaccacaggc ccagcagcgg tccaatgtcc attgcttcaa ggcggctttc cagatcgggg
    45001 agcagcgtgt caaaatcaat gctggtatct ccgataatca ccccggcgct ctggttgacg
    45061 acttgctggg tggcgtcaaa tacgcccata acgatattcc atgtgttcgt cacaatgagg
    45121 atggcaaagg cgcttttgaa aatccagcga aagaacatgg agctgtcgaa gtcgtgcata
    45181 ttgttctttt ctacaatcat gtcgatcagc tcatagcaca tcacaagggc gagaatggcc
    45241 gccgcaatgg ggacgatcac cgtttcagac aggttttgca gcatggaaaa aatgccgccg
    45301 ttccagtcct gcggggtact gcccacatcc gacgcgattt ccccgacttt ggtattgact
    45361 gtgttaaaca ggccggacag gttgcccatg ataccgtcga tcaggattcc tttgatccat
    45421 tccccgatta aatcaccgat catgtgggga cacctccttt cccgcgccct cccagatcag
    45481 agagggcgcg gagagttttc taacacacat ggggttatcc cagcagcccg gacagcagcg
    45541 gaacaagggt catgccgatc agggcaacgc cacctccggc gacaagctgc ttgattccct
    45601 gtgacttgct tgccgggttg tccgccccgt atccctccaa aagattgacg ccgccccata
    45661 cgcaaagcgc cccgccgagg cccacaacga tggtctgcaa agtatcaact gcactattga
    45721 aaaattccat aaatatacct ccataaattc agattgtgat ggtgtttggg tgcaaaaaaa
    45781 gccgccgttc acagcggcag cctcacaatc cgcagacggc ccggagttac tggccgtccc
    45841 gccattccag cacagccagc gaaaaaatct cgccccatgc ttcacacagt ctgcggtcta
    45901 tttcccttgc aagttcttcg gcttccccgt ccgtgggcgg ggtatcatgt tccgcgatcc
    45961 actggcacag caccgcagcg gaaatgatcg cccggtagat ttctttctca tacttgaaat
    46021 aatccgcaaa tgtccattcg tccgagtgtc ccatcggtca cgctcctttc tttgtggccg
    46081 ctttattccg cggcaaaatc ttcctccgac agctcaatgt cgtagaggtc aaagggttcg
    46141 tcctccgtta tcacgcgccg ctttttccgg cgcagggacg acaggtagct gtccacatca
    46201 aaggtattct ttttgtcagc gtccgagagg tattgatagc gggggtggcg ggtgatgtcg
    46261 tatttctcac tgaaaaacgg cctcacgccg cgcacctgca aaatacactt acctccatcc
    46321 atcgttgcaa tttcgtcttg gctcatcagc tcctttccga gtttctggta gttcagtccg
    46381 tgggaggtct gcgcgccccg gttctcgctc tggttatagc tgtcaatggt ttccttgccc
    46441 agcacctccg cgatctcctt ggcgttcttg cccctgccac taaggaacag cgtacagtcg
    46501 cagttgtcgg aaatgatttc cgccgcgtcc ttgtaaatgg cctttagctg cgactggctc
    46561 tgcaaaataa tagaagccga gatttcccgg cttcggatgg tggcgatcag cttgtcaaag
    46621 tttggaatct ggccgatgtt ggcgaactcg tccagaatca gccgcacatg gacgggcagc
    46681 cgcccgccat atttgtcatc ggcccggtca cacaaaaggt tgataagctg gctttgcacc
    46741 attgccagaa tgaaattaaa ggtcgtgtcc gtgtccgaca taatcaggaa cagggctgtt
    46801 tttttatccc cgatggtatc aagttccagt tcgtcgtcct ccatcagctc ccgcacctcc
    46861 cggatgtcaa agggcgctaa tctggctccg cagcttatca aaatggagct gcgggtcttg
    46921 cctgccgaca gcaggaattt acggtactgg cgcaccgcaa agtgttccgg gtctttttct
    46981 tccagccgtt caaacatctg gtctaccggg gattgaaatt ccgggtcgtc ctcgcgggct
    47041 tcgctggcgt ttatcatttc aagaagcgtg gtgaaattca tttcatcgtc cggcgcttcg
    47101 taccagatat agccaatgag ggccgaatac agcaggcgtt ccgatttgat ccaaaaatcc
    47161 tcggcgctct tttcgccctc gcccttggtg ttgcagatca gcgtgtttac cagcttcaaa
    47221 atgtcctttt ccgaatggat gtagcgaaac gggttgtagc gcatactctt ggaaaagtta
    47281 atggtattca gcacctttac ccggtagccg caccgcacaa ggagctggcc cacctcgccg
    47341 atcagacttc ctttcgggtc agtaatcacg aatgaggtcg ggtagtcttt ggacacgcac
    47401 tgcatgaggt tgggcttcac aaagaaccgg gtcttgccgc tgccggaacc gccgatcacc
    47461 agcacatttt tattccgggc ggtcttgggg tctttgggcc ggttgttcat ggtgaggcgt
    47521 tccgtctggg tcaggaggat gttgttgtca aacaccgggt cgatgtacgg ggctatatct
    47581 ttcggcccac cccaacgggc gctgccgtac tcgacgcccc ggcggtattt cttggcgttc
    47641 ttgctcttgc agtacaccat cagccgcagt gccaccgcac cggccacacc caccgccaga
    47701 tcgaacaggt ggaagctggg ggcggcgctt tcaaaggcaa gggaaaagcc gtccgcaagg
    47761 tgcagcagtt tctccgacaa gtccgcccca gccgccagcc ggtaggtctg tctcagcttg
    47821 ccgaacaggt aaacgaacag caggtagggc aggttggcga ttatcagctt tttcatttcc
    47881 ggcttcatcg tgacagcccc ctttccttga ttttctcctt ggcctgctgg ctgcttctgg
    47941 ccgctgcctt ttctttcagg acggcaaggg tttttcggat ggaggggcgt tcctgctgtt
    48001 ggagcttctt ggccgtaaac tccttaaacg cctgttccag attgtccgcc tgcttggatt
    48061 tgaagatcac gatataccgg ggcggatggg tggtgcggtc tttccgcagg gtaaaatcaa
    48121 tgtcgtattt cttggcgcag ggcttaaata agccaatgtt ggcgtcggtg atctcaatgt
    48181 tggacagggc ggaaccgtcc tttttgagct gccgtaagct ctgctggccg tgatgggcct
    48241 tgcccgtccc tttctgccgg gcggccagat attttcggat ggccgcttgc agcacttggg
    48301 cggtgagctt gcccgtctta accgctaacg ctatggtttt ctggtctact tcttcctgca
    48361 actgctatcc ctcctttgga aagtcagcag gcaggcggat ggcttaaatc cgcacccgca
    48421 ggccggagag atcgtcggca tggattccca ccagatacca gttctcggcc atttcaatgc
    48481 gggtcggcct ccatctgccg cccaccatca catcaaaagt ttctccgcag tgcaggccgc
    48541 cgtaatagtc cgcaaggtca aagcggatgt cgtagcggtc tgtctgctcg tcaaaaatca
    48601 aagcaccctg tttcataggg ccgtcctcct ttctcgtcgt cacaagctcc atatcgcttg
    48661 tttccacgca agcgtgaaaa gctcgctcat ttcgctgttt ctcctctccc cacaaaatca
    48721 ccgattttgc ggggttcccc aactgcctgt gttcatgtca tgggccacca gcgccgtgta
    48781 atagccgttg atggtacttg gggcgttgaa cagaaccgcc agcaggtatt ttttgatgtt
    48841 ccgtatttcc gtggtgtttt tgctgataca gtcaaagaca aactcaatgt gagaactgtt
    48901 cagcttcatc agcttggatt tcaccagctc ggcggggtaa tcgtccccgg caatgcggat
    48961 ggtctttcgg gcgctgcata cggtttccac cagcaagtcc acgatctcgt ccagcatatc
    49021 ccggtcaatc cccttggcgt actggcaaag gtgttcatac tcgatgttgt ccttgatgat
    49081 ctcccgataa atctctacgg cgctctgtga tttcgctccc gttcctttcc gttccggcgg
    49141 cgcagccgct tcttccccca aaggagaggg aggggaaagg ataggaatgg aatcggtatt
    49201 tgatccatct gtaattgatt tctctttact tgatctatct ttatttaatt gcgttggttt
    49261 ttcctgcgta ggcttttcct gcgttggatt atccaatgtt ggattttcca atgtaggtga
    49321 atccggcaca ggctggggct gttcgtaaat gatgtaatcc gccccgcgca ggcggccttg
    49381 gctgtcacgc tcacgggaac gcacgatata gcccgcctgt tccagctctc ggacagccgc
    49441 ccggatcgcg tcgatctgct cccggttgat aagggacaag cctttcagcg taaagtccca
    49501 atcctccggc aaggacagca tttgcgacag cagccccttg gctttcaggg acaagtcctt
    49561 gttccgcagg tggtggttgg acatcaccgt gtagccccgg tttttctcca ctcgaaaaac
    49621 tgccatctcg tcgtccactc ctttcacttg aaatttcacc gcgccgtcaa gggcggtgag
    49681 cttgcccggc tggtagggac attcctcata cacacaaaac tggtacttcc agtgcgggcg
    49741 gtagaaacgg caggtgccgc agtcctccgg cgctccggcc tcgccgctgt caaaatgatc
    49801 tgcgcccggc ctcgtctgca tgagctgttc aaaggcccgg tcgctgccgg aagtaaagta
    49861 cataggcggt cgcctccttt ctggttttgg gcgcaaaaaa agcggcgtcc tgatctcccc
    49921 aaaggggaaa agagaacgcc gccgtctgcg gtgtcgtatt cgattttcga tgtgtcacta
    49981 tttgggcggt gggcttcacg ggaggcagaa gcgtgtcaaa gctcaatccg aaagtagtaa
    50041 atcggtagta aattcagttc ttatatcccg tgaaatgccc gtatttccgg gctttttgga
    50101 gataatcaga gttgttttat taatataata agcaattatt atgccataat tttcgatgga
    50161 gaactttgtt ttttataaga atattgaata aatataatca tttatctata tgtatagtat
    50221 aaaaaatgat tgcatagttt caattttcag taaaaaatat tattttgaag aaaatatatt
    50281 ttatatgcta gtttatataa aaaaaatagg aaataaaaaa attatcctat tcctattaat
    50341 tcctattatt tatgtacaaa ataaattata attttagggt acttgaaaaa taaaaaaacc
    50401 tattgaagga gtactttaat cctgaataga tttctttgtt tgataaatta taattttata
    50461 gacctttata ttttaattta ttgtaaaaat cttctccttt ttgagttatt ttacttccat
    50521 atcttcctga actacaaatt ataagttctt ctttttttag atattcaaat atttttttaa
    50581 tttttccttc tgtaatttga aggttcttat cgagtagtgc ttttaaaatt aatcctctac
    50641 caataccaac atctgattcc ttatttaaaa ttagtatctc taatatattc aatatatcat
    50701 tcttactata ttttagtttt aatgatgtat ttttgttatc tgaagacctt aagtttggag
    50761 gtaaatcttt ctctaataca atatcttcac acataatgtt taaataggat gtaacatttt
    50821 ggagttctct tatattacct ttccacatat agttttgtat aagttttttt gcttctggtg
    50881 tgattactaa tttcttatta attaaatctt ccataataat taatatgtct tcttttcttt
    50941 ctcttagagg aggtatattt attggaattg tatttaatcg ataatataaa tcctctctaa
    51001 attggctatt atcaatcatt tgttctaaat tcttatttgt agcagatatg attctaacat
    51061 ctatattaat cacattgtga gaaccaacag gcattatctg tttctcttga agaactctaa
    51121 gtagttttgt ttgtaattct aaaggcatat cgcctatttc atctaagaat attgttccat
    51181 tattagcaag ttcaaataat ccttgttttc catcttttag acctccagta aaagttccct
    51241 tgtcatatcc gaatagctgg ctttctaata aattttcagg aacggctgca caatttactg
    51301 ctataaaggg ttgatttttt ctatttgagt tgttatgtat agactgagct atgagttctt
    51361 taccagttcc actttcacct ctgataagta tgcttaaatc agatttagaa actttcttag
    51421 ctaaatctat acattcaaac attttaggac tatttgtttt tatatcctta aatgtatatt
    51481 ttgctatttg tcctttttct cttaattttt tagtgagatt ttgttctaat ttttttatgt
    51541 atgttatttc ttgtaaacta taatatgtgc ccattttttc atctctattg tatatgtttt
    51601 ttttatttac atttatatat ttcttattga atacgacaac tttatctagt atctctttct
    51661 cactcaataa aacttttaaa ctatctacaa atatatcctc aatgtatttt ccatatatat
    51721 cctcatttat gtctaaaata tcttttactt tactattata tgtatttatt tcaccatctt
    51781 ttgaagtaaa taatatacca tcttttgata aattcaatat tgtatctaat tcttctattt
    51841 ttaaaaataa ttccttatat ttatctttta taccagtatc taaacttatt atttcttctg
    51901 agtatttaac tagattagat tgtatttcct ttgaatcaat ttgtaataaa tttattattt
    51961 ctataaatgt agaaatatct atatatctgt gacctaaatc aaatatatct gagataaagc
    52021 taggtacttt ttctggaact cctggagtta tagctatttt tatattttta tagttattat
    52081 cattcatata tggaattggt ctaatattag tcactccaat tttataaaat aaacttatag
    52141 tttctagagt agtttcatca gaatcattta cgattagaac atttgtaccc tgtggtaaag
    52201 atagtagatt ataaatttta tcttccctaa aagttcttct taccacaatc acttttttct
    52261 tatctagtat attatttata attttgtcta atctttctac tgacattact aatatcacat
    52321 catcatttat aatatcatta tcatttattt catttatgaa gtatctatta atatttatag
    52381 aatctccaaa aactaatttc aaattatttt ctaaaaagtc tattaaatct tttctactat
    52441 catttaccag agctactgat tttttcattt atttctcctt atataataaa tagtttccaa
    52501 caaaatagtt gtataaagca atataatttt gataatttaa atttatcaaa taaaaaagaa
    52561 agtgtctata atgactttat aaaagttgca ttaagacact ttctttctta taattaaaaa
    52621 tcttgtcacc aaatccccct aattgttgct taaaacttaa actgtatgta tatttttcat
    52681 ttctattcga ttaaattata atatacaccc aaaaaaattt attttaataa attctattga
    52741 taatataatt ttgtaaatat agaattatat taaaataaat tatatatgaa aatatatatg
    52801 tataagttta ttctgcgtga gtagaatgaa tttgtcaagt ttaatttagt tgtaatttta
    52861 tcttttatta aaaataatat aaattaaaac atataaataa aatattttat acaatatatt
    52921 gtaaaggagg taactttgat gaaagcagaa aaaacaagta tatatccaat tattaaaaat
    52981 aatttaaaca aaatatcaat tgttgaatat aaaaagggtc aaagatttgt agcatcagat
    53041 aaagacttac aagaagtgtt ctttataata gagggagttg cattagtgga gtgtactact
    53101 agaggaggaa ataaatttct tgttgacatt gtacctgaaa atgaatttat aggcaaaatt
    53161 agttacatat atgaacataa tttgaaatgt gatatatttg caaagactaa tataaaatta
    53221 tttcgatttg aaaaaaatgt atttgaagag ttttatctca aaccagattt tattgcacta
    53281 tttcatagaa aatgtacaag aagaatatat gaattatata aaaccagaat ggtaagagaa
    53341 ctattttctt gcacagaagt tattgcctat tgtatatcaa ataaacaaga aaataatgtc
    53401 tgcaatataa aagctattcg taatttcagt gaaatctatt caattagtag aaaaagtaga
    53461 taccattctc tgctaaagtt aactgaaaag gagatagtaa aaaaaatggg taatacatat
    53521 gaaattttaa actatgatga attacataaa ttggcatttg aagtaaaaga atttttggaa
    53581 gatgagtaaa aattgttact taatcaaaat aaagtataat aatttctgta aaaaatagaa
    53641 atagtctcac tgaaaatcaa aaatacttta gttattttca atgagactgt ttagaaatat
    53701 tgtatactta taatgtatag tataattatt aatcaatttc ctttactata ttaatagccc
    53761 attttttaga taatgctcta ggaacaccaa atataaactt aaccacttct tcactataag
    53821 tgagcaaaac gagtacaaat ataggtgcac ctttaaatgc agctataaaa gttagaggaa
    53881 tagaagctaa ccacatacat cctaattcta aaaatagagc atatttagta tctcctccac
    53941 ttcttaaaat accaattata accaatgtat taaaagattt aagagccatt agtattccca
    54001 ttataaagaa tatcttagtt atatcagaag ctaagctatc agaaacacta aacattttta
    54061 ataataatgg tatatttaaa attaaaataa ttccaagtat taaaccagct gaaaatacaa
    54121 gtatagaaaa ctttttagca tattcaatgg ctcttttaat atggtcagct ccaagttcat
    54181 ttccaagcat aatagatgca ccagatgcaa tacatacagc tgtcattatg aagaaattac
    54241 ctgtactggt tgctatctgg ctagctgcta tagcagaagt accagctctt gcatatgcaa
    54301 cagaatacag gacagttcca attgcccata cagagtcatt tacaaatata ggaaagcttt
    54361 ttgatgaaaa agattttata aaaattttat caatagcttt tagatttttt agaccaaact
    54421 ttaatatata gtctttttta taaaggtaaa cataagtaat cattaaaatt aattcacata
    54481 ttctagcaat aacagtagct agagcagcac cttttacacc caatgcagga agaccgaagt
    54541 taccaaatat aaatccataa tttaaaataa catttgttac aagtgcaaat gcactacaaa
    54601 tcatacctaa cttaggattt ctaacacctc ttgaaccagt actaaataca gtacttacag
    54661 caattaatgg ataactaaat actgcaatac taaagtaatc tatacaaagt tttaccacct
    54721 cagaatcata cgaaaatatg tgtataattg gctttggtgt tagtaaagca ggaataacaa
    54781 atacaaaact taaaacaatt gccaatacac aagtaagacc tgtgactttt cttatattac
    54841 tcacatcctt ctttccataa aactgtgaaa taaaaactcc agcacctcct gtgataccag
    54901 ataaggacat attaaaaaga aagaaaaatt ggtttgcaac tccaactgaa gctacagatg
    54961 tttcccccaa actacttatc ataattgtat ctattacatt tacagaagta gaaattaagt
    55021 tctgtatgat aataggtata cataaagata gaagtatttt ataaaatctt ttattttcgt
    55081 cttttaaaga aaatagttct tgcaaataat cctctccttt ttacataaat tcttcccact
    55141 catcatatag agaggcaagg ttattttcta aattaatttt ttcttggcta acttctttag
    55201 ctttatctgg attagagtat acttcttctt gacataaaag tatatctaat ttttcaattt
    55261 caatctctaa cttttcaatt tctttttcta tattttgtct ttttattcta tttttctttt
    55321 ctatttctct ttgttctctc tcttttcttt tttcatcttt tatttgagtt ctagtttttt
    55381 cttctttttc ttctataata ctcatctctt ggatttgcct ttttttatct atataataat
    55441 cataatttcc cagatattca gtaattccat tttcatctaa aactaaaatt ttatcaacaa
    55501 cagtatttag aaagtatcta tcatgtgata ttgtaaatat agtcccatca taattagtta
    55561 aggcctcttc aaggacttcc ttagaatcaa tatctaggtg attagtaggc tcatctaata
    55621 acaataagtt tgcatttgat agtataagtt taagtatggc aactctagct ctttctccac
    55681 cactcaatgt agaaatcttc ttaaaaactt cttcatctac aaataaaaat gcccctaaca
    55741 tatttctcaa agtagtttga gtaagatgag tattattttc ccaaatctca tcaattattg
    55801 tgttatctaa attaagagtt ttttgttcct gatggaagta ggaaacatgt acattagttc
    55861 caaatttaat attgccacta agaggttgta gttcattagt tattatttta aataatgtag
    55921 atttgccaac accatttgca cctataagtg caactttttc ccctctatat atatctaaat
    55981 ccaagtcttt aaaaagtatt ctttctccat aacccataga tacatctcta atttgaagaa
    56041 catcattacc actctggaca gaaggcgtaa attgtatacg agcttttttc ctataagctt
    56101 ctggtttatc taaaacatct actttgtcta atgctttttc tttacttctt gcacgcttta
    56161 ggtgtttttc tctaccataa gcttttagtc tttcaattga ttcttcttgc ttttttattt
    56221 ctttttgttg gtcttcaaat ttcttaagct ctagttcttt ttctatttta gataactcaa
    56281 caaatttaga gtagttacca ttatatactt taagcttttt attgtgaact tcaaaaattc
    56341 tatttacgga ttggtctaag aaatatctat catgagatat taacatgaca gtccctttat
    56401 attgttttaa aaatacttct aaccattcta ttgcttcaga gtctaagtgg ttagtaggtt
    56461 catcaagtaa caatagagtt ggtttcttaa gaagtaattt tcctaaaaga actctagttt
    56521 tttcaccacc agaaagtatg cttattggct tatccatatc attgtcacta aatcctaatc
    56581 cctttagaac tcctttggct tcagatttat atccatatcc atttaaatct gaaaataatt
    56641 ctagtttatg tgaatattca tccatgattt tttctataat tggagagttt gtttttgtac
    56701 tttcttcaga tattttaacc tccaattctc ttaaatagga ttccatttct atcaaatttt
    56761 taaaaacttc tagtacttct tccaaaatag tattatccga ataaaaattg gtattttgtt
    56821 ctaaatatcc gatttcacaa tctttagaag tgtaaatatc tccactatca tatccataaa
    56881 ttcctgaaat tattttaaat aaagtagttt ttccagtacc attaacaccg attataccaa
    56941 ttttatcgcc ttcatttact gtaaaactaa tattttctaa tatagaatct ataccaaaac
    57001 ttttatttaa gttattacat gacaaaacaa tcataaattt ctacctcctt gaactatcta
    57061 aaattataat gttttgatat aatataatca aggttatatg tattagtttt gaaaaagaaa
    57121 tattttattg tgaatcaaac aaaaaagagg acacttttag gaggtgaaga tgttgggaaa
    57181 taaaaatata tcaatggcag ttataagaag gctcccaaaa tatcatagat atcttggaga
    57241 cttattagat agggatatac aaagaatatc ttctaaagaa ttgagtgata taatagggtt
    57301 taccgcttct caaataagac aagatttaaa caactttggt ggatttggac aacaaggata
    57361 tggttataat gtagaagctc ttcatactga gataggtaaa attcttgggt tggatcgacc
    57421 atacaacgca gttcttgtag gagcaggtaa cttaggacaa gctatagcca attatgcagg
    57481 atttagaaaa gctggattcg agataaaagc tttatttgat gcaaatccta gaatgatagg
    57541 tttaaagata agagagtttg aagtattaga ttcagatact ttagaagact ttataaaaaa
    57601 caataatata gatattgctg tattatgtat acctaaaaat ggagcacaag aagttattaa
    57661 tagagttgta aaagctggaa tcaaaggtgt atggaatttt gcacctttag atttagaagt
    57721 tccgaaaggt gttatagttg aaaatgtaaa cttaacagaa agtttattta ccttatcgta
    57781 tttaatgaaa gaaggaaagt agacaactta aacatattaa taatgagcag ttgtaaagag
    57841 tattgagaaa gtcagaagat ttaatattaa atcctctggc tttttgaaat attaggataa
    57901 aaatttaaat aatgtatgga aataaacaat attaaggaga gtggtttttg tggaggaatt
    57961 atggaaaaag gcaattgaat ttcatggtca tgaatgtcca gggttagcta taggatttaa
    58021 agcagcactt gcagcaaaaa aatatttagg atgtaaacag tcaggagatg aggaaattgt
    58081 atgtatttct gaaaatgatg cttgtggaat agatggtata caagtagtgc taagttgcac
    58141 aatgggtaag ggaaatttac tacttaggat gactggaaaa tcagtatatc atttctttaa
    58201 tagagaaaat ggaaaatcta taaggatata tgtaaagtca aaaccatttg agatggatag
    58261 agaaggatac aaaagatatt tattagaaag tgattttgaa gaaatatttg agattacaga
    58321 tactaagtta agacttcctg aaaaagcaag aatatttaaa tcccttaaat gtgaagtgtg
    58381 tggtgaattt gcatctgagc aatatataag gattgaagaa ggaaagaaag tatgtcttga
    58441 ttgttttgat aaatatgaaa gattttatga agagtattaa aattataaat tagattaaag
    58501 ttaaaagtat tagatatgtg ctaacagtat tttaagatga attaggtagc aacataataa
    58561 agtatataaa taatattaat tgaatcatac ataattaaaa agaggctgat tagtatttat
    58621 aaaataaaat cagtctcttt atgaataacg aattattatt ctggttgagg tgcatctaca
    58681 ggacaagctc ctgcacaaga accacagtct atacaagaac cagcatctat aacatatgcg
    58741 tcgtctccag ctgatataca gctaacaggg cattcagcct cacaagcacc acagcttata
    58801 caagcgtcag taattttata tgccattttg aaatcctccc ttttatatgt attgtaattc
    58861 aataacatta taacaaatat tattgaatat aacaattaaa ttaattctac aacaaaaact
    58921 ttattatgat attcttgttt taaagtttta caataaagtt taatctgctt atatttttat
    58981 ttattttaaa gaagtttatt ttaaaaataa aattaaattt aaaaagttat gtattgatta
    59041 tatttaaaaa tgttatactc taaaaaagta tattttattt aaaaatttat taatacaaag
    59101 gagatttact atgaaaaata aattagttta catatgtatt atgagtctat tgctatttgt
    59161 agtaggatgt tctaataatc caaataagga aagtaccatt aaaaaagact ctaagaataa
    59221 ccaaagccaa gttaaagaag aaaaaagaga acctgtgaaa aaagatataa ctataagttt
    59281 cgctggtgat gtaactatgg ggaactataa aggttcatca tattatggca gttttgacca
    59341 tgaatttaaa agacaaggag aagattacaa ttattttctt aaaaatgtaa aacctgtatt
    59401 tgaaaaagat gacttaacag tggttaattt agaaggtcca cttactacag cgtcaaatgc
    59461 aaaagaaaaa aaatttgcat ttaaaggaaa gcctggatat gtaaatattt taaaatctgg
    59521 aagtgtagag gcagtaagta ttgcaaataa tcattcagaa gattattttg aagaaggaat
    59581 gaaagataca cagtttatat tggacgagaa taaaataaat tattttggat tagggaaaga
    59641 tgctgttgta gatgtcaaag gaattaaagt gggtctatta gggtataatg gattatcaac
    59701 tgaatataat gaaaaaaatt taaaacaaat ggaagatgat attaagtcct taaaaaagaa
    59761 atcggatgtt gttgtagtgt actttcattg ggggatagaa ttagattatt atccagataa
    59821 aaaacaaaaa gattttgctc attatgctat agacaaggga gcagatttag ttatggggtc
    59881 tcacccacat gtgattcaag gaatagaaaa gtataaaaat aagtatatag cttatagtct
    59941 agggaatttt tgctttggag gaaataagaa tccttctgat acagatagtt atatatatca
    60001 acaaaccttt actttttcag ataataaatt aacttcaatt aaagagccaa atataatacc
    60061 aacttcaata acatctagta actccagaaa taattatcaa ccaaaaatat tggatggaag
    60121 tgagaaggat agagttttaa ataaacttga aaaaataagc aaagatttaa ataaataaaa
    60181 tgtaaaaaaa aataaatata tatatttatt ttaataattt atattttgtt tagggtatgg
    60241 taaatcgtgg tattaaataa gtagatttta atagttaaat tatagtcaat tataataaag
    60301 ctatttaatc tactttttta atataaaaat ataaggggga atttgtaatg gcttgtaaca
    60361 cttgtaaaat gtgcgaaagt gcagacaaga aattagaaag ttttgtagct tcaaaggatg
    60421 ttgaaacagc atttcataga acagaagatc agaaagttaa gtgtggtttt ggacttcagg
    60481 gggtttgttg tagactctgt tcaaatggac catgtagagt aactcctaaa tcaccaagag
    60541 gtatatgtgg agcagatgca gacactatag tagcaagaaa ctttttaaga gcagtagcat
    60601 caggagcagc ttgttattta catgtggtag aaaatacagc taagaattta aaaaatgttg
    60661 gaataactaa aggtgttgtt aaaggagaaa aaacattaaa tcaattagca gagatgtttg
    60721 gaatagaaag tgatgaaaag tatgataaat gtataaaggt tgcagacaaa gttatcaacg
    60781 atttgtataa atcaagagat gataaaatgg aattagtaga aaaaatagct tatgcaccta
    60841 gagtgaaaaa gtggaaagag ttaggtataa tgcctggtgg tgcaaagtca gaagtttttg
    60901 atgcaatagt aaaatcatca acaaatttaa acagtgaccc agtagacatg ctagttaatt
    60961 gtttgaactt aggtatatca acaggattat atggtcttac actaactaat cttttaaatg
    61021 atgttatgtt gggagaacca gttataagaa tggctcctgt aggatttaat gtaatagacc
    61081 cagactacat aaatataatg ataacaggtc atcaacattc aacatttgca aatttccaag
    61141 atagattaaa agatgaagat gttataaaat tagctcaatc tgttggcgca aaaggattta
    61201 agttagtagg atgtacatgt gttggtcaag atttacaatt aagaggagaa cattatcaag
    61261 aagtatttgc tggacatgca ggtaacaatt ttacaagtga ggctgtttta tcaactggag
    61321 caatagatat agttctttca gaatttaact gtactatacc agggcttgaa ccaatagcag
    61381 ataaatataa agtaaaaatg gtttgtttag atgatgttgc taaaaaagcg aatgcagaat
    61441 gcataggttt agacagaagt aaattagatg aacttagtaa cactttaata gaaaaagcat
    61501 tggagtctta taaggagaga agaggaagta ttgaaataga tataccaaaa gaccatggat
    61561 ttgaacaatc tttgactggt gtaagtgaaa agaacttgaa agcgttttta ggagattcat
    61621 ggaaacctct tattaattta attgcagaag gaaaaattaa aggtgttgca gctgttgtag
    61681 gatgttcaaa tatgacagca ggaggacatg atgtaaatac tgttgaactt actaaagaat
    61741 tgattaaaaa agatataata gtactatctg caggatgttc tactggagga ttagaaaatg
    61801 ttggtcttat gtcacctgga gcagaagaat tggcaggaga aaacttaaaa gaagtatgta
    61861 agactttagg aataccacca gtattaaact ttggaccatg tctagctata ggaagactag
    61921 aaatagtagc aacagaatta gcagctgaac ttggaattga cctaccacaa ttaccattag
    61981 tgctttcagc tccacaatgg ttggaagaac aagcattagc tgatggagct tttggtcttg
    62041 cccttggctt acctcttcat ttagctttac ctccatttat aacaggagga aaattggtaa
    62101 cagaagtatt aacagaaaaa ttaaaagact taacaggagg acatgttata gtgaatccag
    62161 accctaaatc ttcagctaat caattagaag aaataataat agatagaaga aaaaatttag
    62221 ggttaaagga tgtggaatgc aatgcataga atttttataa ataaagattt atgtacagga
    62281 tgtaagagct gtgtactagc atgtatgcta aaacacaata aagattatga catgtacact
    62341 cttgatttag aaaatataga taatgatagt agagggcata tagaattaga tagtagacat
    62401 aataatccag ttccaattct ttgtagacac tgtgatgaac ctgaatgtgt attagcatgt
    62461 atgagtggtg caatgcataa agatagtgaa agtggaatcg tttcatatga tgaagagaaa
    62521 tgtggttcat gttatatgtg tgtaatgtct tgtccatatg gattattaaa gccagatgat
    62581 agaagcaagc agaacatact taaatgtgat ttatgtaaag atgaggagta tcctagatgt
    62641 gtagctaatt gcccaagtgg agcaattgaa ttacagaagg aggaaaatga tgaattatgt
    62701 agtgttaggg gctagtgcag ctggtataaa tgcagtaaaa acattaagag aattagataa
    62761 agattcaaat atagtagtaa tttctaaaga tgaaaacgta tattcaagat gtatgttgca
    62821 tcacgttata tctgaacaca gaactttaaa acaaataaat tttgttgatg aagattttat
    62881 ggagcaaaat aatgtaaaat ggattgcagg taagactgtt aaaggtatag acataaataa
    62941 aaaggtagtt cagacagaag acattactgt aaattatgat aaacttttaa tagctacagg
    63001 tgcatcttct gctattcctc ctataaaaaa tttaagagat ggaaattttg tatattctgt
    63061 gagaaacata gatgatattt ataaaataaa agaaaaagca caaaattcta aaaatgtagt
    63121 tataataggt gctggtttag ttggtataga tgcattagtg ggattattta aatatgagca
    63181 gttaaatatt tctgtagctt ttatggaaaa gtacatttta gatagacaat tggatgaata
    63241 tacagcatca gtgtatgaaa ataagttcaa agaaaaaggt gtaaaatttt acccaagtgc
    63301 atcaatacaa gaaattgtat tggataacag taaaaatgtt acaggtgttg cattttcaaa
    63361 tggtgaagtt ttagatgcag acatggtaat tgtagctaca ggggttaaac caaatgctga
    63421 ctttttagat ggaacaggaa tagaatatga tagaggtata ataatagatg atatgtgcca
    63481 aacaacacaa aaagacatat atgcagcagg agatgttgta ggtaaaaatg ctatttggcc
    63541 tctggcagta aagcaaggaa ttgtagctgc ctataatatg gttggaaaag ataagaagat
    63601 agaagatgaa tttgctttta aaaatagtat gaatttcatg gatataccaa ctatttctat
    63661 aggaatgaat acacctgtag atgatagcta taaagtatta accagacatg gaattaatga
    63721 ttataaaaag tttgttttta aagataatgt aatctatgga gcagttatac aaggagatat
    63781 ttcatatgta ggtgtattaa cttatttaat aaaaaataaa gttgaaatat atgatttaga
    63841 aaataggata tttgatatat gttatgcaga cttttttaat ataaaagaaa atggagaatt
    63901 ttgttatagt gtatagtata tacgtggagt aaggtttata aatacagtaa atcaataaat
    63961 agagttattc taaaataaga aaaatgacaa atcttattta gaaatagctc tattttttgt
    64021 aattaaattt aaattatatt caatttgtaa aatattattt tgaacaatta tacatatact
    64081 ctctagttag aggtaaatca ttttttatac ctttagtgaa aagtatttga tgtatatcta
    64141 taataccagt gttgaaagca gcagcacaag aacaaaggta taaatcccac attcttataa
    64201 acttatcatc aaacatttct ttaatctttg gaagattctc agagaaattt ttttgccagt
    64261 atagtaaggt ttttacataa tgtaatctta aactttctac gtctatagta tgatatttgt
    64321 aatcactaca aatatgtatc atttctctta ggctaggaat aactcctcct gggaaaatat
    64381 atttttttat ccaagggtct ccataagatt cctgcaatcc acttatatag tgaagtaaaa
    64441 acaatccacc atcttttaaa acagcattta cgtttttaat gaaaagttca tagttttctc
    64501 taccaacatg ttcaagcatc ccaacgctta caactctatc aaacataagg tctgattttt
    64561 ttaattctct atagtccata agtcttacct caagatagtc ttgaaggttc tcttctttaa
    64621 ttcttgcgtt aaattcctta aattgctctt cgctaagtgt aattccaacg ccgtgaattt
    64681 tatatttttt tgcagcttct attagtaaaa atccccaacc acaaccaata tcgagaaggc
    64741 tcataccttc ctctaaattt agtttagtta atatgtggtg aactttattg acttgagcat
    64801 cataaagagt atcattatca tttctaaagt atgcacaaga ataactaagt gtcttatcta
    64861 accataagct ataaaaatcg ttgccaatgt catagtgggc atgtatttct ttcttttgat
    64921 gtctcattga atttgatgag tgcaatagat gttttacagc tgaattatca atattgaatt
    64981 tgtctatttg ttttaaaagt agatttaaag ttaagaataa atctccctca acttcaatgt
    65041 ctctatttat gtaggcttct ccaagtgcta aagatgtact ttttaatagt tcagacttgc
    65101 taatatcatt atttactata actttgaact gaggggagcc ctctccaatt agaaattctt
    65161 cctcatcttt aagcctaact agaaatggtg tttcaccaaa tttctctaaa tagtctttta
    65221 aaaaattttt tgtaatattc atattaccag ctccttctaa tgtaaatcca gtaagtttcc
    65281 ctgcttaaaa tatattatag tccttttttt aaaaaagtaa aattttttca ataaattttt
    65341 tatttaaagg aaatttattt tttgtaaaga aatttcatgt tgtagtatat tttttgctta
    65401 taaattttgg tactggatat aatattaaac tgttaatgat ataataaatt taatctataa
    65461 agtaaataaa attttgtaat aaatagttaa agctatttta taaggagata tatgatggaa
    65521 gtatatgctt tggttgggtc aagtggcaca gggaagagct ttaaggcttt agagttcgca
    65581 tatgaaaatg atatagaata tataattgat gatgggattt taatatacaa aaacaaggtt
    65641 ttagctggga tatcggcaaa acaagcaaat actactatag aagcagttaa aagggctatt
    65701 ttttataatc tggagcatag acaagaagtt agagaagcaa ttaaaaaaga aaatataaga
    65761 aaaattctta ttattgggac atcaaaaaaa atggttaatc aaattgtaga gagattgtca
    65821 attggaaggg tttgcaagtt tataaatata caagatataa gtactaaata tgaaatagaa
    65881 atagcaaaac aagctagaaa agaaggaaat catgtaattc ctgttccagc agttgagata
    65941 aaaagtatgg caagtggtct tagtataaat tctttgaaga gactttttag aaaaggaaat
    66001 aataggaata tggtagtttt agaaaaaaca attataagac caacttttag ttatatagga
    66061 aagttttata ttagtgctga tgtaattaaa cagattattg aatatgaagt atacaacttt
    66121 ggaagcattg atagaataaa taaaatcaat atagagaatt gcaataattt tatgaatatt
    66181 tttgtaagta taaatatcaa tgatttagaa actataaaaa aaattgaaga catacaacag
    66241 acaataaaaa agtctattga gaaaatgact ttagttaatg tacaaaaaat agatattaac
    66301 attcataaaa ttaaaaaaat aaacttcctc caatgttaaa aaataaactg agaaaatgat
    66361 atactaattt gcaataaagt gtgctataat taaactgtaa atttaggaaa tggttttttc
    66421 taaatggagt atacataatt ataacgtatt tataaggggg ctttcaaatg tcaggaaaag
    66481 atgtaaatgt cttcgagatg gcgcaatctc aagtaaaaaa tgcatgtgat aaattaggta
    66541 tggaaccagc agtttatgaa ttattaaaag aacctatgag agttatagag gtttcaattc
    66601 cagtaaaaat ggatgatggt tctataaaaa cttttaaagg atttagatca caacataatg
    66661 atgcagtagg gccaacaaaa ggtggaataa gattccatca aaatgtttca agagacgaag
    66721 taaaagcttt atctatatgg atgactttca agtgttctgt aacaggtata ccatatggtg
    66781 gaggtaaagg tggaataata gtagatccat caactttatc tcaaggtgaa ttagaaagat
    66841 taagtagagg atacatagat ggaatatata aattaatagg tgagaaagtt gacgttcctg
    66901 caccagacgt aaatactaat ggtcaaataa tgtcttggat ggttgatgag tacaataaat
    66961 taactggaca aagttctata ggtgttataa ctggtaagcc agttgaattt ggtggttctt
    67021 taggaagaac agctgctact ggatttggtg ttgctgttac tgcaagagaa gctgctgcta
    67081 aattaggaat agatatgaaa aaagctaaaa tagctgttca aggtatagga aacgttggtt
    67141 cttatacagt tcttaactgt gaaaaacttg gtggtactgt tgtagctatg gctgaatggt
    67201 gtaaatcaga aggttcttat gctatataca atgaaaatgg tttagatggt caagctatgt
    67261 tagattatat gaaagaacat ggtaacttat taaacttccc aggagctaag agaatatctt
    67321 tagaagagtt ctgggcttca gatgttgata tagtaatacc agctgcatta gaaaactcta
    67381 taactaaaga agttgctgaa tctataaaag ctaaattagt ttgtgaggct gctaatggac
    67441 caactactcc agaggctgat gaagtatttg ctgaaagagg aatagttctt actccagata
    67501 tattaactaa tgctggtgga gttacagttt cttacttcga gtgggtacaa aacttatatg
    67561 gatactactg gtcagaagaa gaagtagagc aaaaagaaga aatagctatg gttaaagcat
    67621 ttgaatctat ttggaaaatc aaagaagagt acaatgttac aatgagagaa gctgcttaca
    67681 tgcattcaat taagaaagtt gctgaagcta tgaaattaag aggatggtac taagatttac
    67741 tcttaataaa taataggata taattattta agatataaag gggctgtaca tagtacagcc
    67801 cttaaattat gtggcttaca atgaagtaag ctatttttgt tttaacttat aaataacttg
    67861 ataaattatg taatttagaa tgtatttttt accaccacat gattacaaat tagaggagtt
    67921 agattgaatt tttagacatg aacttatgca ttttaaaagc aaagacctta atttaaagta
    67981 tctagtatta tttttaaaaa tagtatattg gtttaatcca tttatatgta taatggaaaa
    68041 atatatggat ttggattgtg aattttattg tgatgagaga gttttaaaaa attgtactgt
    68101 acaacaaaag caagaatatg ctctaactat tgtaaattca atgaaaagag gtacaaattt
    68161 ttcaaataaa tttgtagctg gattaaataa acaatctgat attataaaaa gagtaatgaa
    68221 catgttcagt gaaaaacata aaaatggtat cttaatggct ttgattataa gcttgttttc
    68281 ttctattaca ttttttaaat tcgattcaac tagtattatt gaagagaatg atttcttaga
    68341 gaggttaaga tatacgtttg aaggaaggca agaagatatg tttgtaacaa tagattttac
    68401 atatgcagat acacctataa aacttagaaa agagcatgaa gaaaactgta gagtcaatgg
    68461 aatagtacca aaagattcag attcaataga aattattcct agattttata aagattgtat
    68521 ggatttaaaa aaataagtta gacttaatat tgatgttgat attatgaatt ttttatattt
    68581 aagcaattga aaattttatt atagattcaa ttttatatgt gtttaagtat gaaatttata
    68641 gatagttgaa ataattaaat atgattgatg cataggaatc attactaagc tataattaat
    68701 tataggggag tttaaataaa ttatgagtta cacaattata aaatgataaa aatagttatc
    68761 tgttacaaaa aatgtatctt tttaattaat aaagataata tgaaaactta aaaggcaaat
    68821 aaacttaaat ataaaatact cttaaataag ataggagaaa aatgtatgtc taactttatt
    68881 ctaaatggga tttttagaac agttatagta agtagtctaa gcattcttct gatattgatt
    68941 ttcaagaaaa atgtatttaa aagatttagc aaaaaattta attattatat atggatgata
    69001 gttgttatta aattattttt accatttaca tattatactt ttacaataaa tatcttgaga
    69061 agtaaaaaac acattaatat taataacata aatttagagg gatttaataa tgtttcaact
    69121 ataagtaata atattatatt gtacacttgg attataactg tagtagtgta tttaatttac
    69181 actatattta aatatataaa acttaaaaat ttaataaatg acttatctta tgatgttgat
    69241 gatagagaga ttgtaaatct ttataaaaat atattagaag aatttaatat aacaaaagat
    69301 ataaaactca aatactctta tgaagttgaa acaccagcat tttttaattc atgtgtactt
    69361 ttgccaccac atgagtataa attgaaagag ttagactgga tttttagaca tgagcttatg
    69421 cattttaaga gtagggacct ttatttaaaa tatgtaatcc tgtttttaaa aacagtatat
    69481 tggtttaatc catttatata tataatggat aaacatatag atttagattg tgaactttat
    69541 tgtgatgaaa gagttttaaa aaatcgaaat tcagaggaaa aaaaggatta tgctttaaca
    69601 attctaaatg caatgagaaa aggttcaaat acttcaaata aatttatagc tggactccat
    69661 aagcaatctg atattaaaaa gagagttatg aatatgttta atgaaaagta taagaatggt
    69721 atattaatgg cattaacttt atgtttatta tcttctatta cttttttgaa ggttaattca
    69781 actagtattg ttaatcttaa tgtattacct aaaggatttg aagacttacg aactgttagc
    69841 agtatacgtt tttcagttat aggatttaca tatgcagatg ctcctaaaaa tatgagggaa
    69901 gaatataaaa taaattgtga atcattaggt ttgataccta aagactctga taaaatagaa
    69961 gttggtatag aatattatga cagtctattg aatgattaaa taaatattat tttaacagat
    70021 attaattata aagttttgaa tagtaatttg ttgagaaata aatatatcct tataaaaata
    70081 gatacttata taccaagaat aaaaaatagt caagatagta cacaaggata tacttataaa
    70141 gaacttaaat aagtgaaata aattattaat tataaggttt ataattttaa aaaattagat
    70201 aaattcaggt gtaaaatact ataaaacaca attcggaaaa gtgtatgttg aacttcattt
    70261 aaaatggaat ttcaaagttg ctatagtaag tagtttaagc attcttctta tattaatctt
    70321 tgagaataat gtatttaaaa aagttagtaa aaaatttaac tattgtatat taatgatagt
    70381 tgctattgat atattatcta aaaaaattaa gtatgaaaag attactgcta ggacaatctt
    70441 ttcatactta atttttaata tttatattat ccaaaatttt catcttttta acttagaatt
    70501 tgagaatcac tattaggaaa taggctttga tttatgtagg gttaaaaatt tcacagcata
    70561 tctaacttta tactaaatcc atcaaaaaat atacgcccta taaaagcgca taaaaaaaca
    70621 cataaaacaa tatttatgcg cactttaacc tcgaatggta caaaattctt tacttttaca
    70681 gacccatatt atataattaa gtaaataatg tatatttagg tgacatattg gataagctaa
    70741 tttatttatt ttattaatat aatgatacta taaaagttat ataaagtggt ttacaaaaaa
    70801 gttacagata gagcttttat taatgtattg tgtattagta ttttatcctt aggtacactt
    70861 cacctacaaa atagaatcat aagataatta tgggaaaatt ttaggaggtt tatcgtgaag
    70921 aaaaagatat taataccagt atttgcatca gttatggcat tatcagtaag ttcaattgta
    70981 aatgcagatg aagtaaatga ttcatctcaa aataaggatg ataaaacaaa tactgaatta
    71041 aatttaggtg aatataaaga agtaaaatat aaagttgcaa aaataaaaga tggagtagct
    71101 ataaagataa gagaagaagg tcaagttcaa aacatagctt attctggaga tgaatttacg
    71161 gttttaggaa ctcaaggaga atgggttaag gttaaagttg aagatggcga aggttggtta
    71221 gctactagat atgtagatat atctgaaggt gtaggatata ctaacgctga taaagtaaac
    71281 ttaagaaaag ataagagtga aagttcagaa gtaattgaag agctggaaaa aggaagttct
    71341 ttattggttt tggaagataa tggagattgg ttaaaagtta aagatgggga aacagaagga
    71401 tatgtaaaat catcttatat atctgataaa gctcctgtaa tagaagagcc acaagtaaac
    71461 ccaagtattg accaaaatgt agattctaca aataataatc aacaaaacaa tgcaaatact
    71521 aatcaacaaa ataataattc aaatgtgcca acagctaact ctaatgcagt tcaagctgta
    71581 cttaacttgg catattctaa gcaaggttgt ccatatgttt ggggagcaga aggaccaaac
    71641 acttttgact gttctggatt tacacaatat gtgtatagaa atgcagtagg aaagaatata
    71701 ccaagaacat ctaaagcaca atctaaatat ggacaaactg taagtaaagc aaatttacaa
    71761 ccaggagact tagtattctt cacaactaat ggttctggtt ctgttagtca tgttggaata
    71821 tatgtaggtg ggggtaatat gatacattca ccatcaacag gaaaaacagt tagtgtaact
    71881 agtataaatt catcatacta tacagcaaga tttgttacag caaaaagaat attataatcg
    71941 gtttgtaata tgacaaattg ataaatacat aaatatatat aaacgctcta tattatattt
    72001 aatttaatca tggaaacaaa aaatgattat attttaaatg tactatagag cgtttttgta
    72061 tcactttaaa tctaatcaag attcaagtta atatgactgt taaataggag ccttttcata
    72121 tgatgattat ttgtgcaatc ccttgacagg atagggcaaa ggtggtaagc tactaacagt
    72181 acaaaaatac ttttaatttt agttcagaga ggctaaaaaa ggaggacgaa agatgttaaa
    72241 atcaagaaat ttaatccaac cagaagactt ttcaatagaa gaaatagatg aaatattaga
    72301 attagctcaa aaaataattg acaatccgtc aaaatattct cgtatatgtg aaggaaaact
    72361 attagctaca ttattttatg aaccatcaac aagaacaaga ttaagctttg aatctgctat
    72421 gaacagatta ggaggacgtg tagtaggctt ttcagagcca aattcatcct ctgcatcaaa
    72481 aggtgaaact ctaggagata caatgaggat agtatctggt tatgttgata taatagctat
    72541 gagacatcct caatcaggtg cagcttcaga agcagctaga tatacggaag tgccatttat
    72601 aaatgcagga gacggcaaga accagcatcc aactcaaaca cttacagact tacttactat
    72661 aaaatcatta aaaggaactt tagaaagcca tacaatagga ttatgtggtg atttaaaata
    72721 tggaagaact gtgcattctt tagttaaggc tatggcaaga tataaaaata caaagtttgt
    72781 atttatagcg cctgaagagt taaaaatgcc agattatata aaagaagcta taaagggaca
    72841 tgcatattat gaaactaata atttggatga tgttatagga agcttggatg ttttatatat
    72901 gactagagtt caacaagaaa gatttgaaga taaatcagag tatgaaagac ttaaaaacta
    72961 ttatatttta aataaagcta aattagaaaa ggcatctaaa gatatgttag taatgcatcc
    73021 attaccaaga gtaaatgaaa tagacataga tgtagatagt gatgatagag ctgtatattt
    73081 taaacaagct aaatatggaa tgtatgttag aatggcttta ataataaaac ttttaggtat
    73141 aaatgaagac taatagttat catataatag taaaacaaag gagattttgg gatgtataaa
    73201 attctggaaa atatatatat aggcgaagat atgtatagaa tgaaagtaaa aggtaatttt
    73261 gaaggtaaaa tgggacaatt ctatatgtta agagcatggg atacttatcc agtactttca
    73321 agacctataa gtatacatga tatagatgaa gaagggataa cttttcttta taaagtagta
    73381 ggagaaggaa ctcaaatttt gagtaaccta aaggtaaatg ataatataaa attggaaggc
    73441 ccttatggta atggatatgc taaggttgat ggaaaggtag ctctagtagg aggaggaatc
    73501 ggtgtagctc cactatattt ggttgctaaa aatataaaaa attgtgatgc atatcttggg
    73561 tttagagaag atgttatatt agaagatgaa tataaacaag tatgtaataa agtctataca
    73621 acagtaggaa atacttttgt aacagatata attgatgttg agaaatatga ttatatatta
    73681 acatgtggtc caactccaat gatggaaaaa ttagttaaga tggtagaagg tactaaaacg
    73741 agaattatgg tatctcttga aaaccatatg gcttgtggag taggtgcctg tttagtatgt
    73801 acgtgtaaaa ctaatggagg aaataaaaag acttgtaaag atggtccagt gttctgggga
    73861 gaggacgtga tttttaatgg gtaatttaag tgtgaaattt ggaagtgtag aatttaaaaa
    73921 tccagtaata atggcgtctg gaacttttgg atttggaaaa gaatataatg agatttatga
    73981 tatacaaaaa cttggtggta taagtagcaa gggtcttact ttaaataaaa aacctggtaa
    74041 caatggtatg agagttcatg agacaccatc cggtatgatg aatagtgttg ggcttgaaaa
    74101 ccctggagtt caaggattta tagactatga attacctttt tttagtaaac tagacttagt
    74161 cagaatagct aatgttggag gtgggacatt agaagactac ttattagggg ttcaaatgtt
    74221 aaatgacaag cctatagaca ttattgaatt aaatatatct tgcccaaatg tcaaagctgg
    74281 tggaatggct tttggtataa aaaatgaagt ggcaagagaa gttgttcgtg aggtaagaaa
    74341 cataacgaaa ctgcctttag taataaaatt atcacccaat gcagaagata ttgtaggaat
    74401 ggcaaaagtt tgtgaagaag aaggtgctga tggagtttca ttagttaata cttttaaagc
    74461 aatggcaatt gatataaaaa atagaagacc agtatttgaa aatgtatatg ctgggttatc
    74521 tggaccagct ataaaaccta tagctttgag aatggtacat gaagtgtgta aaaatgtaaa
    74581 tatacctgta atgggaatgg gcggaataac taaagccaca gatgctatag agtttataat
    74641 ggcaggagct acttgtatcc aagttggaac tgcaaatttt atgaatccta gaataggtat
    74701 tgaaataata gatggaatta atgaatttat ggatagagaa ggaataaaaa gtttagacga
    74761 aataagagga attatataag gtagaataaa tagtatttta aagataaaaa atatagatta
    74821 aataaacaat aattttataa cattaacatg gaggaaaaat aatatgagta aagtagatgt
    74881 agtggatata ttaaagaaaa gtgatgcatt gttggaggga cattttttat tatcttcagg
    74941 aaaacacagt aatagatacg tacaatgtgc aaaagtatta agatttccag aatatgctgc
    75001 tgaggtatta agtacagttg ttgaacaaat aaaagactta gatatagact tagtagtagg
    75061 accagctatg ggtggagtaa tagtttctta tgagttagga agacaattag gaaaagaagc
    75121 tgtatttact gagagaaaag acaatacaat ggagttaaga agaggatttg aagttaaaaa
    75181 aggagcaaag ataataattg ctgaagacgt tgtaactact ggtaaatcaa ctatggagac
    75241 aaaaagagta ttagaagcct taggtggaga agttgtaggt gttgcatgta tagcagatag
    75301 aactaatcat gatataggta tgcctatata tagtgctata aaacttgata ttcaagttta
    75361 tgaatctgat gagtgtcctt tatgtaagga aggaaaatta ccagttgtta agcctggaag
    75421 tagggagttc aaggaattag ggatgtaata aaaacttaat tatttatagt gttacttaaa
    75481 aaatgtaaat tttttagagt aaaaacacaa taaaaatctg attatccgct aaaacacagt
    75541 atctatcagc attttcaagg aaacaaacac atcaatttac tacttattta ctactaacga
    75601 atgagccttg atacgcaagt tttcctagat atgcaaagat atggtacagc acatcagtat
    75661 tgaaacaaga aaaaattgaa taacttatag actatggaac gcctaaaatg acgttccttt
    75721 tctatttcca gccgttctta ttggacggct attttattac ccaaaatgaa aggagcatta
    75781 gatttatgaa aaagacatgg aaacgattgt gtacgggctt cttagctctt gcaactgtcg
    75841 ttactgcttt accgactaca cccgttcatg cagaaagtaa gcaatactgg acggagtcaa
    75901 acgagcgtgt cggtatcgtt gaaaaagtaa tgaatgacgg ttcgattggt tctaccttta
    75961 atgagggaca tttaactgtt gagggcgagg acgcttactg tattgacatt aacacagact
    76021 ttaagaatgg ttacaagacc agagctgacg caagctcacg catgagtatc gaccagataa
    76081 gcgacgttgc cttatctatc gaatatgtaa aacagtacac agacagccac agcggaatag
    76141 gcaaaaatca cgcttacctt ttaagacagc ttgtagtctg gcagagatta agcgtacatc
    76201 ttggctggca atgtgataac gtgcgagctt cttatgatga aattccaaag gcaacgcagg
    76261 acgaagtttt cgctggtgcg aaagcctttg tcaaagaaaa taaaggacgc tatgaatgtg
    76321 gcggttatat ctactctggc gaggggcagg aattgggaca attctgggcg aagctgaatg
    76381 tcggaaatgc gaaactgcaa aagacttcca gtaataccag cattacagac agtaacggga
    76441 attactctat tgcaggtgca acctatggtg tcttttctga taaggactgc acgaaacagc
    76501 ttgccaccct tacgactgat gaaaacggca atacagatgt tgcagaggta aaagctggca
    76561 cagtctatat caaggaatta tccgcaccag caggatataa agtagataaa actgtatatt
    76621 ccttaaaggt tgaagctgga aagacagcta ccttgaaagt atcagataca ccgaaagtaa
    76681 cagacacttt gattgagctt ttcaagattg atatggaaac acagaaagac aatccgcaag
    76741 ggaacgcttc tttagcaggt gcggaattta catggaagta ttatgctggc ttctacaata
    76801 aagaaaatct tcctgccgaa gctactcgta catgggttac aaagacaatc gctgaaacag
    76861 acagcgacgg gacaactcat tacatcacaa aattagcgga cgcatacaag atatctggcg
    76921 acagcttcta tatgcaggac ggtaaggcgg ttcttccact tgggacactt actgttgagg
    76981 aaacaaaagc tccaaacggc tacttgttag acggtgcata tatgcaggct ggcgataagc
    77041 ccgaacagat taagggctta tatgtaacac agattaccga ggacggcgac cttgccgtac
    77101 tatctggaag taaccagttt tccgtatcag acaaggttat ccgtggcggt gtgaaaattc
    77161 agaaacgaga tttagaaacg ggcgatacga aaccacaagg aagtgctacc ttgaaagata
    77221 ctgcctttga catcatttcc ttaaatgata atgcggtatt ggttgagggc aagctataca
    77281 agaaaaatga agtgctaaaa acaatccata cagacattga gggtgtcgct tctacttccg
    77341 ctgacctttt accttatgga aaattccgta tcgttgagag tgaagctcca gacggttact
    77401 tgacagacgg tgcgaaaccg attgattttg caatcacaga aaatggaaaa atcgtggact
    77461 taacagacga agcccattct atctataatc agattaagcg tggagatatt gagggtataa
    77521 aaataggtgc gggcacacat aagcgtcttg ctgatgttcc ttttaggatc acaagcaaga
    77581 caacgggcga aagtcatgtt gtggtaactg atgataacgg tcagttctcc acttctgctg
    77641 actgggcttc tcataagcac aataccaacg caggaaaaac aagcgaggac ggcgtgtggt
    77701 ttggaacttc tgaaccagac gacagcaaag gtgcgttacc ttacgatact tacatcattg
    77761 aagaaatgcg ttgcaacagt aacaaaggct ttgaacttat cccacctttt gaaatcgtgg
    77821 tatcaagaaa taatcttgtg attgatttag ggactttgac tgatgaatac gaaaaagaaa
    77881 tctctatcca taccacagcg accagcaagg acggcgaaaa gactatcctt gcaggaaaag
    77941 aggttacaat cgttgatact gtcaaattag acggacttac aaaaggcaca aaatatcagc
    78001 tcaaaggctg gcagatgtta aaggaagaaa acgcagaact tcttattgac gggaaacgtg
    78061 tagaaaacga ttataccttt gtcgctgatg atgaagaaat gaaagtggaa atttcctata
    78121 tattcaatgc gtctgcttta ggtggcaaga accttgttac ctttgaagaa ttgtatgatt
    78181 tcagcaatcc agacgaaccc gtaaaagttg cggaacacaa ggacattgag gacgacgggc
    78241 aaaccgtact tatcacagag cgtatcatca aaattcatac gactgctacg gataaggacg
    78301 gcaacaaaga gcttgaagct ggaaaagagg taacaatcat tgataccgta accttagagg
    78361 gcttagaagt cggtacacag tacaaacttg tgggctggca gatgttgaaa gaagaaaatg
    78421 cagaacttct tatcaatgga aagcgtgtgg aaagtgatta tacttttact gctgacagcg
    78481 aaactatgaa agtggaagtt gcttttacgt ttgacgctac ttctcttgac ggcaaacagc
    78541 ttgtaacttt tgaagaattg tacgatttaa gcaatccaga cgaaccgaag aaagttaccg
    78601 agcataagga tattgaggat aagggacaga cgattacctt taaggaaaag ccagaagaac
    78661 cagagaaacc cgaaacacca ccgacaccag aaaagcctaa cagacctagc gacagtccca
    78721 aaacgggcga cagtacaaat gtaatggcat ttgtcgtgat gttgcttgcg tctgctggtg
    78781 gactggctgg aacatatctt tacaaacgcc gtaaaatgaa gaaatcgtaa ggcggtaacg
    78841 gtatgatgaa agaaaaatca cgctctccgc cgaagctgtc aaacggcaga cttccgctta
    78901 ttctggcttg tctgcctaca acctgcaaga acacggatag tcaagggtgc gtaagcattg
    78961 attttaccct ttactatctg ggggattgct ggtacttccc aaaccgccag aataagaaat
    79021 cacaatcaaa aaacttatca aaaataaaaa gaaacgaggt aaaacaatat ggaaatgaaa
    79081 tatgtcgtgc cagatatggc acagtctttt ggaacacttg aatttgcagg cgaaagcgag
    79141 ccagtctttg aaagagataa aaataaccgc agggtcttag ccagacgaag ctataacctt
    79201 tattctgacg tacagaaagg cgaaaatgtt gtcgtggaaa ttcccgtgca ggctggcgaa
    79261 aagcatttca agtatgaaca gaaagtaaaa cttgtcaatc cgaagttata cggcagaggt
    79321 tatgcaatcg gggatatggg acataccgat tatgtgttag ttgctgatga tattgtagca
    79381 gttgaagaaa agtaaaggag tgaagaattt atgagattat caaacgggtt tgttattgac
    79441 aaagagaaaa catttggaga attaaaattt acagcggtgc gtgatgtgtt cttgcagaac
    79501 gaggacggaa caccgagtac ccagcttaaa aagcgtatct atgatttgaa gtgcagtctg
    79561 catggtggaa ttatccccgt gtctgtaccg ccagaagtac cgttaagaga atttccgtac
    79621 aatgcagtcg tggagcttgt caatcccgta gcagatacgg tatcaagaaa gacgtttggt
    79681 ggtgcagatg tggactggta tgtaagggca gaggatattg tgttgaagaa taaaggcaac
    79741 cagaacgcag gcaatccaca gaataataac acgcagggac agccgaaaaa acaaaattag
    79801 agattagatt tttattgtga ggtaattcgt tgaatgatat aattaggata aattgtgagg
    79861 tgcttatcta tgaaagtatt agttagttca tgtatcatgg gaaaaaactg caaatataac
    79921 ggtgggaata atctcaatcc gaaagttgta gagtttctaa aagacaaaga ggttatcgaa
    79981 atttgtccag aattattagc gaatatgcct acaccacgtc ctagtgcgga aatagtaaat
    80041 ggtattgtca tggatataaa tggaaatatt gttgatgagg aatatcgtca tgcggtacag
    80101 ttggctctaa atgaaataag aagtatggaa atagatttag ttattctgca atcaagaagc
    80161 ccaacttgtg cagtcaagaa tatttatgat ggtagtttta cgggaaaatt gataaaaggt
    80221 caaggtctgt ttgcacaagc gttaattgag gctggatata aagtgttgga ctcagaagat
    80281 ttttaatgaa tggtaatgaa aaggcagtta gtcttaggat tgactgcttt tttcataccc
    80341 agaaaggagt gattgattta tgcaaaagat ttggaataaa ggacaccgta tcagagccag
    80401 cgacaagcac cttgtctacc acttttccat agggacgctt ctgtttgtat ttgtgacggt
    80461 tcttttgcta ctgaatatca aacagctcat gtgtaccgat tgggaacatt tcagtttgtt
    80521 agagaacggc ttgacgctct ccccttacaa cttcataacc atactgatag cgactggtgt
    80581 ttgtgcattg gtcgcttttc tgtattaccg cttctgttac gacaatttca agaagctcct
    80641 gcaccgtcaa aagctggcaa gaatgatact ggaaaataag tggtatgaag ctgataccgt
    80701 gcaagacagc ggttttttta ctgacctgca aagcagatca agagaaaaaa tcgtctggtt
    80761 tccaaagatt tattatcaaa tggaaaaagg actgcttcat atccgctgtg aaatcacgct
    80821 ggggaaatat caagaccagc ttttacggtt agaggataaa ttggaaagtg gcttatattg
    80881 cgagctgacc gacaagaccc tgcatgacgg ctatatcgaa tataccctgc tttatgatat
    80941 gatagcgaac cgtattacca ttgatgaagt acgagcagaa aacggctgtc ttagactgat
    81001 gaaaaatctt gtctgggaat atgacgcact tcctcatgct ctgattgctg gtgggactgg
    81061 tggcggtaaa acttattttc tgctgacact cattgaagcc ttactgcata ccaacgctgt
    81121 tctttacatc ttagacccga agaacgctga ccttgcggac ttagggacag ttatgggaaa
    81181 tgtatatcac accaaagaag aaatgataga ttgcgtcaat gccttttatg agggtatggt
    81241 acagcgaagt gaggaaatga agcgacaccc gaactataag acgggcgaaa actacgccta
    81301 tctgggactt cccccctgct ttcttatctt tgatgaatat gtggcgtttt ttgaaatgct
    81361 ggggacaaaa gaaagcgtga gcctacttag ccagttaaag aaaatcgtta tgttagggcg
    81421 acaagcaggt tatttcctta tcgtcgcctg ccagcgtcca gacgcaaagt atttctcgga
    81481 cggtatcaga gataacttta atttccgtgt gggattgggg cgtatcagcg aattaggtta
    81541 cggtatgctg ttcggttcag atgtaaaaaa gcagtttttt cagaagcgta tcaaggggcg
    81601 tggctattgt gatgtgggga caagcgttat cagtgagttt tacacgcctt tagtcccgaa
    81661 aggacatgat tttttgcaga ctatcggctc tcttgcacaa gcaaggcagg acgggacggc
    81721 gacgtgcgaa gcgaaaggcg acggcacgga ctagccgttg ctggtgtggc gttagccacg
    81781 ccagcaggta aaacccctcg gtatctaaca gaggggtacg tttgcaaata gacaatagac
    81841 aaaaaacata ggaaacataa ggcttctgat atggttttct agtaaaaatc agttgtgaag
    81901 tcgccttaaa aaacttcaca ctttacagat tgggggtatg gttctgaatg aagaacaatg
    81961 gataaaagaa ttacgggaga aacggattgc ttacggtatc tcacaaggca ggctggcggt
    82021 ggtttctggt atcacaagag aatatcttaa caagatagaa agcggaaaaa tgaagccgtc
    82081 aaaagaactt ctggaaactt tgaataagga actggcaagg ttcaatccag aagcaccgct
    82141 taccatgctg tttgattatg tgaaaattcg ttttcccacg ctggatatac agcacatcat
    82201 caaagatata ttaaaactga atatcaatta tatgctccat gaagattacg gacattacag
    82261 ttatacggag cattattctt taggggacat ctttatctat acgtcggctg acgaagaaaa
    82321 aggtgtcctt ttagaattaa aggggcgtgg ttgcaggcag tttgaaagtt acctgctggc
    82381 acagcaaaga agctggtatg acttcctcat ggacgcactc atagacggtg gcgtgatgaa
    82441 gcgtattgac cttgctatca acgaccatac gggcattttg gatattccag agcttgcgga
    82501 aaaatgcagg aaacgggaat atatcggaaa gtccagaagc tataagtttt atcagtcggg
    82561 cgagcttatc aagcacagag aggacgacag agaatatatg ggacgtaccc tttatcttgg
    82621 ttcgctgaaa tcagatgtgt atttctgtat ctatgaaaag gactatgagc agtatgtcaa
    82681 gttagggaca ccacttgatg aagccgacat tatcaaccgt tttgagatac ggcttcgcaa
    82741 tgaacgtgct tactatgcag tacgagattt gctgacctat tatgacgcag agcagaccgc
    82801 cttttctatc atcaaccagt atgtgcggtt tgttgatgaa gaaccagaca agcgaaaaaa
    82861 tgactggaaa ctcaatgacc gctgggcttg gtttatcggc gataacagac agagtttgaa
    82921 gctgacgaca aagccagagc cttatacctt agaccgcaca ttgcggtggg tacaaaggca
    82981 ggtagcaccg accttgaaaa tgctgaaaaa gattgataaa ggaaacggta cagattacat
    83041 ggaaacaatc gaacagcagg caaagctcac agaaaagcat gaaatgataa tcaaacagca
    83101 gacgacccct gcaaaagatt tagtagaaag ttaggagtga taaaaaatgt gggtattatt
    83161 aaaagacttc ctgctggtat ctatgggaat gggtatcggc gtagtcttga tgtgtatttt
    83221 gaatgtcggc aaagaagctg actgtgaaat gaaacaatta aaagaaagtg aggacaatta
    83281 aatgaattt
//
LOCUS       DAMKNB010000008        83191 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.008, whole genome shotgun sequence.
ACCESSION   DAMKNB010000008 DAMKNB010000000
VERSION     DAMKNB010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 83191)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 83191)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..83191
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.008"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            complement(121..894)
                     /locus_tag="PC494_000644"
     CDS             complement(121..894)
                     /locus_tag="PC494_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SigB/SigF/SigG family RNA polymerase sigma
                     factor"
                     /protein_id="HDF3911170.1"
                     /translation="MKNVANATHYLNMDTKELFNLYNKNKNVDIRNILIERHLYLARL
                     LAKKYINKGVDFEDIYQVASLALIYAIDRYDVEKGFEFSSFATPTIVGEIKKYFRDKV
                     WTLRVPRRIQELSKKISDAKIKLEQENKKHPKVKDIADYIGVSEEDVLEAMEASYGYQ
                     PMSLDSSSNDDSEDKDITLIDKIGKEEGNFGSIEYEDFINKFIETLNELEVKIFKDRF
                     FFDKTQSSIAKELGISQMTVSRLEKKVVEKLKKEYEKNL"
     gene            complement(894..1280)
                     /locus_tag="PC494_000645"
     CDS             complement(894..1280)
                     /locus_tag="PC494_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HDF3911171.1"
                     /translation="MEITTNPDYVSIIRLTASGIANKMGFPIDDIEDIKVAVSEACTN
                     AIKHSKDDVFNIVFNILDNAINIEIQDNGKGYDVSSISTPDLENPKESGLGLFIIKTL
                     MDDVDIESEHNQGTKIKMTKYLGVDI"
     gene            complement(1305..1622)
                     /locus_tag="PC494_000646"
     CDS             complement(1305..1622)
                     /locus_tag="PC494_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="STAS domain-containing protein"
                     /protein_id="HDF3911172.1"
                     /translation="MSMNIDSNLDSQNKFWNVCLDGELDVSTADKLKEHLHALIEKNM
                     LDVKINLKDLDYIDSTGLGAMIGVLKKLKINEKEIYIVNPKSNVRKIFTITGLDKIFK
                     VEG"
     gene            complement(1634..1894)
                     /locus_tag="PC494_000647"
     CDS             complement(1634..1894)
                     /locus_tag="PC494_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HDF3911173.1"
                     /translation="MNAWGWQIGAVLVGSSALIVAIYLAKTLNSINKVVEKAYKIVDY
                     NERHIQDIVENASSISKGIDDIVYVINKILSIGNIFKIIKRK"
     gene            complement(1894..2190)
                     /locus_tag="PC494_000648"
     CDS             complement(1894..2190)
                     /locus_tag="PC494_000648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HDF3911174.1"
                     /translation="MCNKRSCKKGGFLLLGAILGFIFGMFFAPKKGSELRKETKEKFN
                     DVKENPKEVLHETFNDVKERIINLVDDDNNEEDIKISEEDIVISKSFDDEGDVN"
     gene            complement(2259..4685)
                     /gene="gyrA"
                     /locus_tag="PC494_000649"
     CDS             complement(2259..4685)
                     /gene="gyrA"
                     /locus_tag="PC494_000649"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HDF3911175.1"
                     /translation="MEENNKILPIEIAEEMKKSYIDYSMSVIAGRALPDVRDGLKPVH
                     RRILYSMSELNLTPDKPYRKSARIVGDVLGKYHPHGDTAVYYAMVRMAQDFSTRALLV
                     DGHGNFGSVDGDSPAAMRYTEAKMSKLSLELLRDIEKETVDFKPNFDESLKEPSVLPA
                     RYPNLLVNGSNGIAVGMATSIPPHNLAEVIDATVYLIDNPECSVDDLIKFVQGPDFPT
                     AAIIMGKESIAEAYRTGRGKVKVRSRAFIEELPKGKQQIIVTEIPYQVNKAKLVERIA
                     ELVKEKRIEGISDLRDESNRNGMRIVIELKRDANANIVLNNLYKHSQMEDTFSIIMLA
                     LVDGQPRVLNLKQILYHYIKHQEDVVTRRTKFELNKAEARAHILEGLKIALDNIDAVI
                     SLIRASKTGQEAKLGLIEKFKLTEIQAQAILDMRLQRLTGLERDKIEAEYEDLIKKIN
                     RLKEILADERLLLNVIKDEITIIKENYSDERRTEIRHAEGEIDMRDLISDEEIAITLT
                     HFGYIKRLPSDTYKSQKRGGRGISALTTREEDFVRHLVTTTTHSRLLFFTNKGRVFKL
                     NAYEIPEGKRQAKGTAIVNLLQLSADEKIATLIPIDGNDENEYLLLATKKGIVKKTKR
                     EEFKNINKSGLIAIGLRDDDELIGVELTDGKQEVLLVTKEGMSIRFDENDIRYMGRTA
                     MGVKGITLSKEDFVVSMNLCSKGTDVLVVSKNGFGKRTNIEEYRSQIRAGKGIKTYNI
                     SEKTGTIVGADMVNEDDEIMIINSDGVLIRIRVNEISLFGRVTSGVKLMKTNDEVNVV
                     SIAKINIEEE"
     gene            complement(4705..6606)
                     /gene="gyrB"
                     /locus_tag="PC494_000650"
     CDS             complement(4705..6606)
                     /gene="gyrB"
                     /locus_tag="PC494_000650"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003226808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HDF3911176.1"
                     /translation="MKQEYGASQIQVLEGLEAVRKRPGMYIGSTSPRGLHHLVYEVVD
                     NSIDEALQGYCSDIYVSINEDGSVLVKDNGRGIPVEIHPKTGKSTLETVLTNLHAGGK
                     FGGGGYKVSGGLHGVGVSVVNALSKWMVAEVYLNGKIYKQTYEKGLPTSKLEVVGESQ
                     DKGTMIQFMPDETIFDEIEFKYETLEYRLRELSFLNKGIKIVFEDKREGQEKRKEFHY
                     TGGLVEYIKYLNKSRTGIHDDIVYIDKKVDDCFVELAMQYTDGYTENIYSFANNINTH
                     EGGSHLSGFKAALTKTVNDYAKRNKFLKENDVNLLGEDIREGLTAVVSVKLPEPQFEG
                     QTKTKLGNSFMRGIVDSVTVDELGSFLEENPSTARIIVDKALRAQRAREAAKKARELT
                     RRKSVLESTSLPGKLADCAEKDPSKSEIFLVEGDSAGGSAKQGRDRNSQAILPLRGKI
                     LNVEKSRLDRILSSDEIKNMITAYGCGIGEDFDIDKARYHKIIIMTDADVDGAHIRTL
                     LLTFFFRYMRPLIDEGYVYAAQPPLYKVTKQKKEHYVYSDKELNILLDEIGRNGVELQ
                     RYKGLGEMNAEQLWETTMNPETRTLLQVTVEDAAIADEVFSMLMGDKVAPRKEFIEEN
                     ARFVRNLDI"
     gene            complement(6607..7722)
                     /gene="recF"
                     /locus_tag="PC494_000651"
     CDS             complement(6607..7722)
                     /gene="recF"
                     /locus_tag="PC494_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HDF3911177.1"
                     /translation="MKLKSLQLVNFRNYKKLHLEFNGKVNLLVGKNGQGKTNIVESIY
                     MLSFGKSFRTNKDKEMVRFNSENLYIGGSFSKYNKYSLIELIIGKDKKGIRINKVPLQ
                     KIQELLGNLNVVIFSPEDLRLVKEGPKERRAFIDKEISQIIPKYYKYLTNYNKTLSQR
                     SRVLKNIHVDEALLDVYDDTLAKYGSYIYILRRDFIKKIANISENMHMNLTNGVERLS
                     IRYKNQINITDEDTIDTVYNKFLAKLSSNRPNDIESKTTRYGIHKDDLNIFINDLDAR
                     LFGSQGQQRTASISLKLSEIELIKNEVEEYPVLILDDVFSELDEARQKLLVNNLSNVQ
                     MFITSAEVSHKKIFDEKNVTIFNIENGDVISIENGGN"
     gene            complement(7740..7946)
                     /gene="yaaA"
                     /locus_tag="PC494_000652"
     CDS             complement(7740..7946)
                     /gene="yaaA"
                     /locus_tag="PC494_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HDF3911178.1"
                     /translation="MTEITIESEYIKLDQFLKLAEIASTGGHAKFLIQEGLVTVNDEI
                     ELRRGKKIKSGDIVEIEGTKIKVL"
     gene            complement(8083..9189)
                     /locus_tag="PC494_000653"
     CDS             complement(8083..9189)
                     /locus_tag="PC494_000653"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HDF3911179.1"
                     /translation="MKIICNQKILANRIGIAQKAINGKTTIELLKGILISTEEGQLKL
                     TGYDAEIGIETYVQAEIIEKGDVVVDARLFGDIIRKLPDSFVEIETDSENNIYINCVN
                     SRFKIKGYAAKEFPKLPELNEEDLYSIPQEILKNMIKQTVFAISQDQTKPVLMGELLE
                     IVDRNLNLVAIDGYRLAVKSCSVDSLTENIKVIIPGKTLIDVNSLLSGEDNVKVGFNE
                     KNAIFIINDTKIITRLLEGDFIDYKKLLPREHNSRVKLNTKELLNSIERASLLSQSEK
                     NNLIKLSIRDKVMAITSNTEKGNVYEEVEIDLDGDYLDIAFNSRYFIEGLKNIDNEEI
                     FIEFTTNVNPCIIKPTDDVNYIYLLLPVRISSNI"
     gene            complement(9431..10753)
                     /gene="dnaA"
                     /locus_tag="PC494_000654"
     CDS             complement(9431..10753)
                     /gene="dnaA"
                     /locus_tag="PC494_000654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000428021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HDF3911180.1"
                     /translation="MMDIVSLWDKTLQLIKGDLTSVSFNTFFKNIVPLKIHLNDLILL
                     APSDFNKDILENRYLHLIEDAISQLSLKKYNIKFVLSEKEVADLNSDSTDLNYRVLYP
                     NLNPKYTFDTFVIGNSNRFAHAACVAVAESPAKAYNPLFLYGGVGLGKTHLMHAIGHH
                     IVSQKKDSKVVYVSSEKFTNELINSIKDDKNEEFRNKYRNVDVLLIDDIQFIAGKERT
                     QEEFFHTFNTLHEANKQIIISSDRPPKDIPTLEDRLRSRFEMGLITDIQAPDFETRIA
                     ILRKKAQLERIDVPNEVMSYIAKNIKSNIRELEGALTRVVAYSSLSNRVISFDLATEA
                     LKDIITTSKNEEINVLRIKEKVSSVFNLKMEDFNSKKRTRSIAYPRQIAMYLTRELTD
                     LSLPKIGEEFGGRDHTTVIHAHDKVSKDIEESEEIKTKIDKIISDLKG"
     gene            11409..11546
                     /gene="rpmH"
                     /locus_tag="PC494_000655"
     CDS             11409..11546
                     /gene="rpmH"
                     /locus_tag="PC494_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HDF3911181.1"
                     /translation="MSKRTYQPKKRQRSKEHGFRKRMKTSNGRNVLKRRRAKGRNRLT
                     H"
     gene            11624..11968
                     /gene="rnpA"
                     /locus_tag="PC494_000656"
     CDS             11624..11968
                     /gene="rnpA"
                     /locus_tag="PC494_000656"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HDF3911182.1"
                     /translation="MDFNRTKGLKKDSDFRKVYKHGKSFANKYLVIYILKNKSDYSRV
                     GISVSKKVGKAITRNRVRRLIKEAYRLNIDEKIKPGYDIVFIARVSSKDATFKDIDKS
                     IKNLVKRTDISI"
     gene            12000..12251
                     /gene="yidD"
                     /locus_tag="PC494_000657"
     CDS             12000..12251
                     /gene="yidD"
                     /locus_tag="PC494_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HDF3911183.1"
                     /translation="MNKIIYILKEISKYLSNLCIYLVRFYQKYISPLKGPTCRFYPTC
                     SQYSIEAFKKYGFVKGMYLTIRRILKCHPFHPGGYDPLK"
     gene            12283..12990
                     /locus_tag="PC494_000658"
     CDS             12283..12990
                     /locus_tag="PC494_000658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HDF3911184.1"
                     /translation="MNIIGNFLGLILKVIFEFVNHYGISIILFTILVKIILLPLTIKQ
                     TKSTKAMQDIQPRIKEIQEKYKNKPEKQNEEIVKLYGEAKINPLSGCLPLLIQFPILI
                     GLFSVLREPVAHGVFANKAAFLAADNGFLWIKSLTSPDYVLAVFSGASAYVMQKVMTP
                     KDQLQGSMKVMTYVMAGMSFYWGFIFPAGLTLYWTVSNLFSIAQYYLIMNPLKAKLAA
                     NSKEEKVNEKKPKINKK"
     gene            12959..13588
                     /locus_tag="PC494_000659"
     CDS             12959..13588
                     /locus_tag="PC494_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein jag"
                     /protein_id="HDF3911185.1"
                     /translation="MRKSLKLIKSKSKEEAISKAIAELNLKAEDIEVEILENPSKGFL
                     GFIGAKDGTYEIFVIEREVDVAKNFIEVMLKNANVDAKVNVSQKDNLIMVDIEGKEAA
                     SLIGRRGETLDSIQFLTGLALNKINKDSHTRVLVDIENYRSKREESLIRYANKVAREV
                     AKTRKTKKLDYMNPYERRIIHSALQNDKYVITYSEGTDPYRRLVIECKR"
     gene            13700..15079
                     /gene="mnmE"
                     /locus_tag="PC494_000660"
     CDS             13700..15079
                     /gene="mnmE"
                     /locus_tag="PC494_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HDF3911186.1"
                     /translation="MFIDDTIAAIATAPGEGGIGILRISGEKALKVAEEIFKSMSGKS
                     IEEYNKRTLIYGNIVDNENIIDEVLLAYMKGPNSYTGEDVIEINCHGGFISVKKILEL
                     ILSKDVRLAEAGEFTKRAFLNGRIDLSQAEAVIDVIKAKTDIAHEVAQNQLEGSLSKK
                     IRELRDKVTEILAHVEVAIDYPEEDIEHITYQTLKEKTDELKKDIKKLYDTAESGKIL
                     REGLKTVIVGKPNVGKSSLLNSILGENRAIVTDIPGTTRDVIEEFVNIKGIPLKIVDT
                     AGIRDTDDIVEKIGVEKSKESFTSADLIVMVLDASRKLSEEDIEILEKLKDKQTIVLL
                     NKNDLKQEIEEEKILKYVENNSIIKISALQQEGIEELQDKIESMVYKGSIKNNSSLVV
                     TNSRHKDALSKAYKSATDALIALEQSMPFDFVEVDLKNIWDYLGYINGDTVTEDLLDN
                     IFHNFCIGK"
     gene            15177..17069
                     /gene="mnmG"
                     /locus_tag="PC494_000661"
     CDS             15177..17069
                     /gene="mnmG"
                     /locus_tag="PC494_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012065747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HDF3911187.1"
                     /translation="MKFEAGKYDVIVVGAGHAGCEAALATARMGYKTLIITMSLDSIA
                     LMPCNPSIGGTGKGQLVKEIDALGGQMGLNIDKTYIQSRMLNTAKGPAVHSLRAQADK
                     FKYHEEMKKTLEDEPNLDIAMDEVVEILHEGNVVIGVGTKLGCSFKSKAVILATGVYL
                     NSKIYMGEVAFYEGPNALGYAKYLTDSLVELGLRMRRFKTGTPARVHRDSIDFSVMSL
                     QEGDEKVTPFSFMNENIEKKQEPCYLTRTTEETQKVILDNLKRSAMYSGVIESTGPRY
                     CPSIEDKVVRFSDKTSHQLFIEPEGLNTKEMYIQGISTSLPFEVQLDMYKTIKGLENC
                     KIMRPAYAIEYDCVDPTQLKISLEIKGVENLFSAGQFNGTSGYEEAAAQGLMAGINAV
                     RKIEGKEPFVLDRSEAYIGVLLDDLVTKGTNEPYRMMTSRAEYRLYLRQDNADMRLTQ
                     KGYDIGLVKKDRYERFLNKKAAVEKEFERLKNERVTPKEVNSLLEEKGATPIKVGISL
                     YEFLKRPEVTYELLEELGKGAGEDVSREVKEQCVIITKYEGYIEKQLKQIDQFKKLEN
                     KKLDEKINYSSIEGLRLEARQKLDDIKPISIGQASRISGVSPADISVLLIYLEQIRRT
                     RGGKGE"
     gene            17062..17781
                     /gene="rsmG"
                     /locus_tag="PC494_000662"
     CDS             17062..17781
                     /gene="rsmG"
                     /locus_tag="PC494_000662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HDF3911188.1"
                     /translation="MNNIELLKNGIEGFNIDTNDSMLEKFKIYREILVDWNKKMNLTG
                     IEDEKEVYIKHFLDSISAVKNGYIKNGMSIIDVGTGAGFPGIPLKICLDSLELTLLDS
                     LNKRINFLEEVSRVLELDNITFIHGRAEDFGKNEDYREKYDVATARAVAGLPILMEFC
                     VPFVKVGGYFICLKGPNANLELEESQKAIDVLGLEYIEKIDVELPEVDLNHNILVFKK
                     VMETPVKYPRKAGKPAKNPIK"
     gene            17944..18729
                     /gene="noc"
                     /locus_tag="PC494_000663"
     CDS             17944..18729
                     /gene="noc"
                     /locus_tag="PC494_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid occlusion protein"
                     /protein_id="HDF3911189.1"
                     /translation="MEDKRVMEIPIEDVVPNPYQPRKIFSQVSLEELSNSIKVYGIIQ
                     PITVRAKDGKYELIAGERRLRAAKLAELKTIPAIINNMNDESSAVLALLENLQREDLN
                     FIEEAIGYENLIKEHAFTQQQLAEKLGKNQSTVANKLRILKLPNDIKMKLIENNLTER
                     HARAFLKLPSEDLMQSVLDKVIKNELTVKKTEKLIQDVLEETKVQEEPDKKQNIKGAM
                     SIRIYINTIKQAFDAISNTGIDAKYNEIDKGDYMEVVVKIPKK"
     gene            18864..19637
                     /locus_tag="PC494_000664"
     CDS             18864..19637
                     /locus_tag="PC494_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HDF3911190.1"
                     /translation="MGKVIAVFNQKGGVGKTTTNVNLSASLGTLGKKILVLDLDPQGN
                     TTSGYGINKNEVENTIYEIMLDGLHIKEAIISTEFENVDVVPSATELSGAEIELTSKT
                     NREYILKNSIKAVIDEYDYIFLDCPPSLGMLTINCLTAVDSVLIPIQCEYYALEGVSQ
                     LMETIKLVKSRLNADIEIQGVVLSMFDGRANLSIQVVEEVKKYFKGSVYTTLIPRNVR
                     LAEAPSHGKPVIYYDKRCRGSVAYLELAEEFIDLEEEEW"
     gene            19639..20502
                     /locus_tag="PC494_000665"
     CDS             19639..20502
                     /locus_tag="PC494_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HDF3911191.1"
                     /translation="MENKSKRSNRLGRGLSALIPEIKGETSEKEIVNIDIDKIYPNEV
                     QPRKQFDEEKIKVLSDSIKNYGVLQPIVVKMDENNKYMIIAGERRFRASKLANKNQIP
                     AIIKDIDMKDIMEIALIENLQREDLNSIEEALAYKSLIEHYNVTQEEISEAVGKSRPH
                     ITNTLRLLNLGQDVIEMIDSGRITAGHGKALLRIADKDLQLQIAKKIEEEELSVREVE
                     NIAKKISENKQEEPKKSKPKDVFILDVEDKLRNIFGTKVNISKGKKKGKIEIEYYNDD
                     DLNSIVSMLLE"
     gene            20535..21677
                     /locus_tag="PC494_000666"
     CDS             20535..21677
                     /locus_tag="PC494_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
                     /protein_id="HDF3911192.1"
                     /translation="MIYLDNAATTYPKPERVYNAVLDCMKNYCANPGRAGHKLAMRAA
                     REIYDTRENIAKLFNVSNPMNIVFTSNATDSLNLAIKGVLQEGDHVITTSMEHNSVIR
                     PIKALEKRGIENTVVKCDYEGFLDYEDLEKSIKSNTKLIVTTHASNVCGTLIDIKKVG
                     EIAKKHNILFLVDASQTAGVYDIDVNECNIDMLAMPGHKCLFGPQGTGILYVREGLNL
                     NILKEGGTGSKSEEIVQPELFPDKYESGTHNTPGIAGLNQGILFIFERGINNIRQHEE
                     ELCQYMIDKLEEVPDIKIYGPKDSKKRASVIALNIGDMDSGEVTFLLDSDYNIATRSG
                     IHCSPLAHTTLGTLKQGAVRFSIGYFNTKDEIDKAVEALKKISKNK"
     gene            complement(21810..22385)
                     /locus_tag="PC494_000667"
     CDS             complement(21810..22385)
                     /locus_tag="PC494_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GerMN domain-containing protein"
                     /protein_id="HDF3911193.1"
                     /translation="MKNKKIMLVLSILSISIFAVGCTNAQNGSDSSKKETKSNTNVEQ
                     PKEENNTEKEVPNNKAKLTPKEETKAQSATIYSFDVDKTDLIENKVDLNKIDENTLFE
                     ELQKLKVVPESAKLNSFTTKDIDGVKTGILDVSSDFTKSNLGSDAETLMLDSVARTYI
                     KNMNVEQIKITVDGSNYESGHIVLEEGDYLK"
     gene            22645..23937
                     /locus_tag="PC494_000668"
     CDS             22645..23937
                     /locus_tag="PC494_000668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HDF3911194.1"
                     /translation="MEILSLGEKIKKLRKEKNMTLKELAGDRITAAQISHIERDKSHT
                     SYELLEYLGDKLDVSVEYLLETKEMQSKKITDNLILQSEIYIKENELNKAEDQIKEVL
                     DICKRYDLMENYGRCNFLMANINLKKSNYNDAIENFEKALYFFIKNSDSENILKCYLN
                     IGKIYMQEDFYKGAISHFNFAEEILSENKFEDVNIHKELYSKMAYCYIKLDNPNMSLK
                     YIEKINEIDNRNDRKEDVDILVLKANNMLEIGKYEESRDYFKKALKILESEDNKTGLA
                     NVYLTICDVYRKIGETDRVLEYSQKVYDIKKNDEDEYMMSGLFKIIEAYIDKEDYDLA
                     RKYCKIALASSIKNKNKFNEYKALRFYANMYKNQNEVTLAIEYLIKCIKIVSDLGNNR
                     ILANLYIDLGQLYSNISKEKELEYYQKGVFMYKNLEIM"
     gene            24042..24644
                     /gene="yedF"
                     /locus_tag="PC494_000669"
     CDS             24042..24644
                     /gene="yedF"
                     /locus_tag="PC494_000669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfurtransferase-like selenium metabolism
                     protein YedF"
                     /protein_id="HDF3911195.1"
                     /translation="MSIKIDARGLACPKPVINTKRELDNLEEGVVVTIVDNETAKENI
                     LKLAKSLSCEANIVDEKENFISIEIRKGKNILDKQNVVDNKESELDNTCIFISSDKMG
                     LGNDELGKVLIKGFIYTLTESKPYPKYVLLVNGGVKLSAENEETIENLKILENMGVEV
                     LSCGTCLDYYNLKDKLQVGTVTNMYTIVETLKNASNTISI"
     gene            24717..24980
                     /locus_tag="PC494_000670"
     CDS             24717..24980
                     /locus_tag="PC494_000670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3343 domain-containing protein"
                     /protein_id="HDF3911196.1"
                     /translation="MNQMYIVSFNSTHHAIRSEKLFGENSLKVMALPTPREITASCGI
                     SIKFSFEDMEKIKTILVENNVDIKGIYCISKLENGSKEVEKLD"
     gene            24995..25180
                     /locus_tag="PC494_000671"
     CDS             24995..25180
                     /locus_tag="PC494_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 domain-containing protein"
                     /protein_id="HDF3911197.1"
                     /translation="MPMDLKIGDIVELKKQHACGCKEFEIIRTGMDIKIKCTKCSRLI
                     MLDRETLEKRVKKLIKK"
     gene            25283..26479
                     /locus_tag="PC494_000672"
     CDS             25283..26479
                     /locus_tag="PC494_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HDF3911198.1"
                     /translation="MAVKYAKRMQGLQGSEIRELLKLTQQPQIISFAGGMPAPELFPV
                     EEMKKVSVAVLEENGRSAMQYTTTEGYEPLREKIAARMNDKNKTNVNKDDILVTSGSQ
                     QGLDFAGKVFIDEGDVILCESPSYIGAINAFKSYQPKFIDVPTDSDGMIMEELEKILE
                     TTDRIKMIYVIPDFQNPTGRTWPLERRKKFMEIVNKFEIPVIEDNPYGDLRFEGETLP
                     SLKSMDTKGLVIFLGTFSKIFCPGYRLGWTCASPEILSKFNFAKQGADLQASTISQME
                     VSKFMDMYDLDAHVDKIKAVYVKRRDVMLKTMEEEFPEGLVFTHPEGGLFTWVELPSN
                     LNAKELMPKCLDKNVAYVAGGGFFPNGGRENTFRLNYSNMPEEKIIEGIKNIAAVLKE
                     AMGVEA"
     gene            26693..26971
                     /locus_tag="PC494_000673"
     CDS             26693..26971
                     /locus_tag="PC494_000673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HDF3911199.1"
                     /translation="MRNYELVYVVKPNSDEEVREAILNKVKEVVATDGEIVKVDTWGT
                     KKLAYPIAKFTEGFYVLVNFKSAVDVPKEIDRNLKINENVIRHMIVVA"
     gene            27008..27442
                     /gene="ssb"
                     /locus_tag="PC494_000674"
     CDS             27008..27442
                     /gene="ssb"
                     /locus_tag="PC494_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HDF3911200.1"
                     /translation="MNQVVLVGRLTRDPELRYIPGTGTPVASFTIAIDRDYVKKDGSK
                     ETDFIPVEVMGKSAEFCANYITKGRLVALQGSIRVDNYQTQSGEKRTFTKVSTRSVQA
                     LDSKNKSENSYRESAPAFEPSFEPQGLDPQGFQAIDDDDIPF"
     gene            27461..27688
                     /locus_tag="PC494_000675"
     CDS             27461..27688
                     /locus_tag="PC494_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HDF3911201.1"
                     /translation="MMNKKRRKKKRVCQFCADKNAKIDYKSTQRLQKYITERGKILPR
                     RISGTCAKHQRELTVAIKRARNIALLPYTLD"
     gene            27831..28151
                     /locus_tag="PC494_000676"
     CDS             27831..28151
                     /locus_tag="PC494_000676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like family protein"
                     /protein_id="HDF3911202.1"
                     /translation="MKIDKGSEITRNIKIIEWMKTEILMSVSDLFNLLFKGVKPLDEA
                     IQDTLANIIMITYLLAKRLGISFRDVDYKVKEKIKIGIDEDHSVERWYGDLSNLKKHM
                     DNRE"
     gene            28159..29115
                     /locus_tag="PC494_000677"
     CDS             28159..29115
                     /locus_tag="PC494_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YybS family protein"
                     /protein_id="HDF3911203.1"
                     /translation="MNNKIRLSKAMSIIVLAIIIALVIAYIPMLGIFSMLAAVPYVII
                     GAITDRKYSLISILVTFCVLILFADISYALNICIMYSLPGIVIGKMLKRSFEQEDSNK
                     FEPIYGGTIIFVLSMLVYFFVLKTFLNVNLLDEVSKMISEIVNIQKNSFSATELKVFD
                     KMKPDEIVSYFTNMLPMMLFLQGLLSAFVTYYLSVFFIKRITKMNIRFPKFADFYLPG
                     NAILTTFLLYLLVLFIQIIGSKLYTELIMTNLQLVFNLMFVIQGIAVCIYFLKKWIRQ
                     GPNKIMFFSGIILCLFGFMGISFVGMVDSIIDFRKVRSYKST"
     gene            29126..31120
                     /locus_tag="PC494_000678"
     CDS             29126..31120
                     /locus_tag="PC494_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HDF3911204.1"
                     /translation="MSNKQTFKLNMPEINLYIIVIGISSIILLYYNLYVGCLFFCIFV
                     YMVFHNWRTTNIRRHEWTEYIQNLSLDIDETTKKAIINLPIPLCILEFDGNISWYNGK
                     FYDMIGQKDLLDKNIEDIVKNLNLRKVLNENKEMYTEINYKEKEYTIIYNVIKNDQEK
                     NPKYLMILYWIDKTEYLKVKQNYDDEKNAMMLIQVDGYDEVLKSAAEDKRALINVEVE
                     KILSALELNSNGALRRTSKDKFFLVMHKKELKKLEAEKFSILDTIRHIDYGNNLPVTI
                     SIGIGIDGDTLNENLKLATGALDLALGRGGDQAVVKTKDKFVFYGGKSKAVEKKTKVK
                     SRLIGHALREVIQQSDQVYIMGHKYPDMDAMGAAVGVYDICKSCNKTANIVLQSVNES
                     IEIFINKINENNYYKKLFIGKEEAIDNCTKNTLVVVVDTHRPNYTECEELLKLSEKVV
                     VIDHHRRGVEFINDAVLLFHEIYVSSTCEMVTELVQYMDEDVTINKLTAEGLLAGISL
                     DTKNFAFKTGVRTFEAASYLRKVGADTIEVKKFFNSDVKDFIIKAEIIQSTKIINNRI
                     CLAYSSTEIDSINVIIAQTADELLNIKEVEASFVLGEKDDTIFISARSLGQINVHVLM
                     EKLGGGGHIDIAGAQLKNVSLKEAYKMVNKIIEEYLEEEE"
     gene            31121..31570
                     /locus_tag="PC494_000679"
     CDS             31121..31570
                     /locus_tag="PC494_000679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HDF3911205.1"
                     /translation="MKVILLKDVKGTGKKGEMKEVSDGYARNFLFPKKMAVQADSVAI
                     KELNEKNKSKEIKAQKEYEEAVLLGKQMEEINIEIYSKAGEGGRLFGSITSKEIAEQL
                     KKQKDIDVDKRKILLDEPIRSLGSTFVEIKIHQKVTTKIRVDVKEKQ"
     gene            31589..32917
                     /gene="dnaB"
                     /locus_tag="PC494_000680"
     CDS             31589..32917
                     /gene="dnaB"
                     /locus_tag="PC494_000680"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HDF3911206.1"
                     /translation="MEDMTRIPPHSVESEQSILGSILLDKDAIITVTETIKPDDFYKE
                     AHKIIYECMITLSNKGEPIDLITLTEELRKQGHLNDIGGISYITSLSTIVPTTSNVKY
                     YADIVKEKSVLRKLIKASNEIINLGYSGATKIEDVLEQAEKSIFDISQEKTSDDFKSI
                     NLVLMDAYDMIEKLYTNKSDVTGITTGFKDLNKKINGLQRTDLILIAARPAMGKTAFS
                     LNLVQNAALKGDASVAVFSLEMSKEQLVQRMLSSQSSVELKKIKTGTLNDNDWPRIID
                     AMAVLSDAKIHIDDTPGIKISELRSKCRKLKIEKGLDLVLIDYLQLMEGEGNNESRQQ
                     EISKISRSLKILAKELNCPVVALSQLSRAPEQRADHRPMLSDLRESGAIEQDADIVMF
                     LYRDEYYHADSESKNIGEVIIAKNRHGETGSVELVWLGEVQRFGDKLRDL"
     gene            33122..33430
                     /locus_tag="PC494_000681"
     CDS             33122..33430
                     /locus_tag="PC494_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3911207.1"
                     /translation="MEKISLKYIYPNIIKVLDEINLFRVIDNNLRESIVVYANNVDNQ
                     YHINMTNTNFGNIINICKLEKLLDVDKFMEKVIKYEKEIIEKEEFSKIEEYMLNIGEY
                     "
     gene            33512..34801
                     /locus_tag="PC494_000682"
     CDS             33512..34801
                     /locus_tag="PC494_000682"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HDF3911208.1"
                     /translation="MKTVAIVGSQWGDEGKGKVIDYLATQADVVVRGQGGNNAGHTLV
                     VEGKKYALHLIPSGVLNPNTVNIIGNGIVFDPKGFLEELEMFKTDNISTENIKISDRA
                     HVIFPYHKELDALSEEARGDLKIGTTKKGIGPCYMDKTERSGIRICDLMDKDKFAIKL
                     KAQIDAKNEIVKNIYGKEELFDFETIYNEYLGYAEQIRKYVADTSVIVYDAVRAGKKV
                     LFEGAQGTLLDLDLGTYPFVTSSHPTSGGFAIGAGIGPNMIKDVVGIVKAYTTRVGEG
                     PFVTEQINETGDKIREQGHEFGVTTGRPRRCGWFDAVIVKYAARVNGLTSISFMLLDV
                     LTGFDKIKVCTSYKMGDKIITDFPASLDDLAKCEPVYEELDGWNEDITQIDNFDDLPE
                     NAKKYVAKIEELVGVSVDMVSVGPNRAQTIIRRNIFA"
     gene            35127..35202
                     /locus_tag="PC494_000683"
     tRNA            35127..35202
                     /locus_tag="PC494_000683"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:35160..35162,aa:Lys,seq:ttt)
     gene            35209..35283
                     /locus_tag="PC494_000684"
     tRNA            35209..35283
                     /locus_tag="PC494_000684"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:35242..35244,aa:Glu,seq:ttc)
     gene            35288..35363
                     /locus_tag="PC494_000685"
     tRNA            35288..35363
                     /locus_tag="PC494_000685"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:35321..35323,aa:Val,seq:tac)
     gene            35397..35471
                     /locus_tag="PC494_000686"
     tRNA            35397..35471
                     /locus_tag="PC494_000686"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:35429..35431,aa:Thr,seq:tgt)
     gene            complement(35854..36846)
                     /locus_tag="PC494_000687"
     CDS             complement(35854..36846)
                     /locus_tag="PC494_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HDF3911209.1"
                     /translation="MNEDKIRKILAKYAKRRDDNELLLEHRKNEVYNRIPEIKSIDDE
                     ISKIGLSLAKIVLLNPKSKDEIVKKTKENIESLKVKKERLLAESNIPLDYLEIKFQCI
                     SCKDKGFLPNGEKCSCLKQEIVNEAYKMSNLDRILSQENFSNFNLNIFSPKKGSDGEI
                     SPRENMLNNLSICENFVHDFKKDNSENLLFYGSTGLGKTYMCNCIAKELLDKGNVVIY
                     QTSFRILDILEDYKFRRDTNNQISEDNYKNLFDCDLLIIDDLGTELNNSFTSGEIFNI
                     VNTRLVAGKKIIISTNLTPSQIGNTYTQRTLSRILDKFRILEFTGDDLRWERFK"
     gene            complement(36855..37913)
                     /locus_tag="PC494_000688"
     CDS             complement(36855..37913)
                     /locus_tag="PC494_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HDF3911210.1"
                     /translation="MFFKESNEIDLGEITIPNIFIDIFMPMADGLYVKVYLLGYRQAC
                     DITSNPKFDNNSIAKNLNIPLSDVLSAWKFWEEKKIIKIHDNGEYDNFNYSIEFLDLK
                     NFYIENILSNNSSIKSNTDKVVSTSENPSIRKMFNSINKIVGRYLDPSEKMSIMDIMN
                     KYNMSPDMILCAYEYVKDKTGTSKPVKYIEGIIRNWYDSNLYTPKDVEESFLVRSERY
                     ILYKTIFNELGFSRQPSKSEKELMDTWFDKFNMDIDLIINACSKSKNISNPSISYING
                     IIKNWNEKNIKNLNDLKQKEEERIVKENINKKQINTTQNNNTYKKTKFHNFNETFTQY
                     TSDELDEIIKKSQKEKFK"
     gene            38038..39501
                     /locus_tag="PC494_000689"
     CDS             38038..39501
                     /locus_tag="PC494_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M1 family metallopeptidase"
                     /protein_id="HDF3911211.1"
                     /translation="MVIKFNQKVRRTLSVAILFMVLIIGCFIEKDDSLETYKEKTNSK
                     INQYNMDVIFDDETKRLMCNQNVDYINNTKSNLDKIYFHIYPNAFSKKDFAPFEKSEM
                     TRAYPNGFNEGYIDIKNILNNNSKMEYKIKGDKNDILEIELGKELKPNERMSLDIKYN
                     VKIPNSIGRFGYGENTINVTNWFPIACVNDERGWNLKSYETIGDPFYSETSDFHVKLL
                     IPNKYKIAHTGKLIDDKHDNKKMLYEIEAENVRDFAFILSSKFNVNKVDSKGVAINTY
                     NLNKKLSKKATEVAKDSINIFSELFGKYPYKEFSVVASDFFIGGMEYPMLVMIDQSLY
                     NEKNEFLLEYVIAHETAHQWWYSAVGNDEISEPWLDEALTEYSTIVYFEQKYGKDMAN
                     KLIKTMEIQTKSYLSENIFKPANEYKNSTEYSLNVYTKGAIAFNEIRKEVGDKVFFET
                     LNEYYNKYKHKNANGRAFVELWNSKGVDINKIISECK"
     gene            39603..40400
                     /locus_tag="PC494_000690"
     CDS             39603..40400
                     /locus_tag="PC494_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HDF3911212.1"
                     /translation="MLKYCSVGSGSSGNCHYIGYKNTNILVDAGLSGKRITTGLKDIG
                     VDADKLKGIFITHEHVDHIKGAGILSRKFDIPVFANIKTWCSMKDKLGDIKDKNMKVF
                     ENDKTYSLGDIIVRPFSIEHDASDPVGYNFYTESDEKMSIATDIGCITQNIKKHLYKS
                     KLVVLESNYDPNMLMMGSYTYALKKRVMSSTGHLSNEDAANFCVELINEGTESILLAH
                     LSKENNFPELAYETSKGVLASNDIVVGQDVKLDVLSRNDVSNVYEMK"
     gene            40413..42515
                     /locus_tag="PC494_000691"
     CDS             40413..42515
                     /locus_tag="PC494_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC/EAL
                     domain-containing protein"
                     /protein_id="HDF3911213.1"
                     /translation="MLKRNFENVEDNKILYSIKQGMILAIPAIMTGSTALVILNLPIK
                     AYQEYLSGLFNGEVTNILNFINDSTLGIISLIILLTISYSYGKIYGSKYTVLVPIVAM
                     CSFLVFSHGNELNSYIEIFKTKWLFTSIIVSMTSSVLFVKLTESFVTSVKFHTEGADA
                     DFNMVVSAIVPFIIVVFLFSIFRVIMISLIGSSNFQDIFYNLFSNVFNKMGTNLMSAL
                     LFIFLMHFMWFFGIHGSNVLDTVAKNLFENSMAININLVNNNQLPTEIFTKTFFDTMV
                     LLGGCGSLLCLVIAIFLSEKRINVRKLAKIASIPALFNINEMLVFGIPIVFNYIMFVP
                     FVITPIILTITSYVAMSTGIVPCTVSAVEWTSPIFLSGYMSTGSIRGSLLQVFNLCVG
                     VMIYIPFIKMSQNRYTYMFKNNIENLTNLLKRYELTGEQPNLLNHNGKIGSISKMLAS
                     DLKFAMKRGEIELFYQPQVNYNGNVVGAEGLLRWKHSIGGFIYPPLVIILAKEEGFLD
                     ELGEYIINKACIDLKKSEKLLRNPVKFSVNISPDQLDDPKLPEQIKNIISSNDINPNM
                     LGIEITEQIALSGSQIIIERINAIHNLGIKLIMDDFGMGHSSLIYLQNNNFDIVKLDG
                     SLVKEILTNKRSSEIIMTIVNLSKNLDFDIVVEYVENIDQRDKLYGLGCEIYQGYYYS
                     KAIPFEEFVEYANQEREI"
     gene            42583..43062
                     /gene="rlmH"
                     /locus_tag="PC494_000692"
     CDS             42583..43062
                     /gene="rlmH"
                     /locus_tag="PC494_000692"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001027003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HDF3911214.1"
                     /translation="MNISIVVVGKIKEKYLKLGIDEFKKRLSKYCKLEIIELDDEKAP
                     ENLSVKEMEIIKDKEGKKILGKIKHNSYVIALAIDGKGLSSEELAKTMSDLAVRGNSS
                     LCFIIGGSLGLSDEVLGRADYRLSFSRMTFPHQMMRLILLEQIYRAYRINNGEPYHK"
     gene            43129..44820
                     /locus_tag="PC494_000693"
     CDS             43129..44820
                     /locus_tag="PC494_000693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3911215.1"
                     /translation="MDRLDIFIENYDFKEYLEKLPRELIEENYKDFVIEFWKNPSVDI
                     IKLKSKYSIKNVVSISSILMQNPIQEYYEFLEDIWKNNIKIDELINKYLITATRMDQI
                     KFPLIYIDEDSFCPYCLGNKFNIINNIKQQDIKVECEKCGEAISYFIHKEEVDNIIEE
                     EKRKKELFIRTLENVYNKINKIKCHRCQSDLYVCINDKIMEYNIRCDRCNSQYESVEI
                     AQEQYRLWQQRAAMMANIKNKENELLLKTLSIKDEKDIKFKLEDIITESESIDVISDL
                     VDMQDRGENIFKQLFNNYVRLGRLDRRLLVTVCKDCKQNENTYTWERGKEHLINMRGI
                     TYSEAVVYELMEKTKLLPIRAIIRRLMEKKLLYCDERSNNLQVHPVLIENLAKLESIN
                     KSQNINNQVAYLIFNKQKYICYHCGESGRPLKIGYLTIDKNINDLSSLVGICDSCYED
                     ITEDEIIIDNIFCVVDERNNELGEAWKFLIQYDSSFRNNTIAEVEHARLYDMYDEDNL
                     IRAYANTLYKQTKDGFANEKVFFAYARAILKNSKGQVSVLQIAKEKFKLEKWLNG"
     gene            45052..46524
                     /locus_tag="PC494_000694"
     CDS             45052..46524
                     /locus_tag="PC494_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3911216.1"
                     /translation="MSHSKLSDHKLKKGKFIAPFNEFMTPLNSNESWCLGRLPEYIWI
                     GLLINKYGRKKGMEIIYKIIVKLHSIESDIVTPRLSEILSMEDVKQDEFFSYILTIVE
                     KEALSPLTLIFTYSNYPIFVKYFAEPSIKIEDRVTYLDETLRKAMHHQSEFATDIRFI
                     VLYYFCMSGKLVLQKEQINNLLEYPNLEHTDEKMRMLRPFIRAAELMVLNMEKKSDWY
                     LDIFWGRISVMTECKLYATKFEDETANTDLYMEQLHEIFVYLSDLLCKVNPLDEKMLV
                     LLGIAIYSYKRLREVVEHKLFNSISGRGSVRVLIENYIMMKYLVKIEAQHENIWSEYQ
                     FYGIGQYKLIVARYREQEQDLKNSHVDYKYIEALVNEFVIEETIDMDTKYFDKQNIRS
                     KAEIVGEKELYGLYYDYDSAYEHGLWGSIRESSMLKCDNPAHHYHCIPDVDNNQNLKS
                     VWHDCVNIMEKTLLFLDTVYGIPQHLLLEVIKNGKEFFTK"
     gene            46499..47563
                     /locus_tag="PC494_000695"
     CDS             46499..47563
                     /locus_tag="PC494_000695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3911217.1"
                     /translation="MEKNFLLNKINSIQKEYLELLVKLKDNIDTIDYIYIIDEINIFW
                     YSYRDVIKLYLGNITQKDNAYIFTGATYLDVDDLEHYPFVMMGDIHIVDDSLCKYSKT
                     VLVLSNQEFAKVLKDQIISCIDDNIKILSNYSFAMLILPMNLLYGNDMKIIHEYSNNI
                     FLNFFSRKDLNLDTYFEEFNSIEDIALALNPGIESYIVFDEGEDLTKNLEERFKSFID
                     KGKVPLPAHKSDAFKFWLIIYGFITQALDIILSCKGFNLTPYLRYRVTLQYVLLLGDN
                     VFDIEDLSNMLLKCKVAHVLYAIFDKSEIKNISFVQFYKKLSEYKFSYKVENDIKENI
                     NINQIAEILNKNITLFLNYI"
     gene            47703..48875
                     /locus_tag="PC494_000696"
     CDS             47703..48875
                     /locus_tag="PC494_000696"
                     /inference="COORDINATES: protein motif:HMM:NF013752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDF3911218.1"
                     /translation="MLKQNTIQIDYTTYGNNYQFKLPLNIDYMIPKDAIFVDGTKIES
                     SANRYTFVWKKTINKNMVRVMNDISNFILKCGIDFGIKIIYRNKIKIYHLKKLLKKLK
                     KISKESNITFVHGKGKKKSIVQKSIAKLNNYIDRLKKYTKDLHIMGELNSYSKTDNDA
                     TFMRMKKDHMKNGQLKPAYNIQFGVDSEYIVWVSSEHKPTDTTTSIPFLKSIEEHTKF
                     KYPKIVADSGYESEENYTFLECNNQLSFIKPANYEISKTRKYKNDIGRIDNMDYDEKK
                     DYYICKNGKKLFANKIINRKSKTGYKSKITCYTCKECCDCQYKNGCIKGNNSKIPLEN
                     RTKNLQVSKLFHEKRKENLKRIISQEGCQLRMNRIIQAEGTFAQVKQNMKFRRFLS"
     gene            49317..49628
                     /locus_tag="PC494_000697"
     CDS             49317..49628
                     /locus_tag="PC494_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDF3911219.1"
                     /translation="MIKIMLACSAGMSTSLLVTKMESAAKENGIESQIWAIPESTIQN
                     EIEKCDVLLLGPQVRYVLPKAQEIARPYNIPVEVINMMHYGTVNGEAVLNRAIELNNT
                     K"
     gene            49676..49993
                     /locus_tag="PC494_000698"
     CDS             49676..49993
                     /locus_tag="PC494_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HDF3911220.1"
                     /translation="MDEKIIEISFNIIGYAGEGKGLAFEAIKEAKNGNIEKAKELLKE
                     SREVINKAHRYQTELIQNEASGNRTEISVILIHAQDHLMNGMNFQQLAEEIVDLHLKL
                     QDK"
     gene            50206..50907
                     /locus_tag="PC494_000699"
     CDS             50206..50907
                     /locus_tag="PC494_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDF3911221.1"
                     /translation="MLRNQPLYIQVVDILKQKILNNEYKIDENIPTERELEQEFGVSK
                     ITIRKAIEILESEGYVEKKSGKGTKVISNSLFNKLSKAESFSSILLSKGHKLSKKTIS
                     IEKIINDTNSQVFSIFGEKCSKITRMYYLDSKPYIFFTHYIPFDENLTVESFNNESSL
                     YMYLYRRNINITRFEDEFFIEESELEVSKALNLAKDILLGRKRKTYDENDNIVELSFA
                     RYNTEVQNYVIKYEI"
     gene            51132..52433
                     /locus_tag="PC494_000700"
     CDS             51132..52433
                     /locus_tag="PC494_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDF3911222.1"
                     /translation="MEKFASFLERKIMPVAAKISNQRHMRAVRAGIIATLPLTIVGSF
                     FTILLNIPIDAYMDFIAPFKAILDIPFRYTVGFLSLYATFGIASSLAKSYDLDTTGVG
                     MLAVMAFLVSTIVPTQVVEPVGGVIEAGRWMDMAKLNSPSLFGAIVTSLITVEIYRFM
                     KEKNITIKMPAGVPVEVSNSFTALLPTAVILMLFWVIRHILGFDISVALSAMLSPLKG
                     FLSGNSLGGGLLTVFLITLFWVLGIHGPAIMGPVIRPIWDMSIAENITAFTEGVSAHA
                     MPNIFTEQFLQWYVWIGGAGATLALVVMFMFSKSQYLKSLGRLGFLPGLFNINEPIIF
                     GAPIVMNPILGIPFIIGPIIMTILSYVLTITGVIPMMVARLPFAMPAPIAAVMSTNWS
                     ILAGILVLINFVISFAVYYPFFKVFEKQQLQREQEEMSENL"
     gene            52570..53664
                     /locus_tag="PC494_000701"
     CDS             52570..53664
                     /locus_tag="PC494_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HDF3911223.1"
                     /translation="MERRLGISVYPEHSNMEDDKAYIKMASKYGFKRIFMCMLSITRP
                     KEEVKKHFKEIITYARELGFEVILDIAPNIFDILQISYDDLTFFSELNASGIRLDYGY
                     DGSKEAMISFNPYDLKVELNMSNDVAYLDNIITYKPNVNNIYGCHNFYPQRGTGLPYD
                     FFVRCSNRFKKYGIRTAAFVNSKYATIGPWNINDGLCTLEMHRNLDIATATKHLFATG
                     LIDDVIVGNAYASEDELKRMSEVNEYQVVFNVVAEEKTSEVEKIIMVNEQHFRRGDIT
                     NQVARSTEVRKKYAKENFPKHDNKNLFKRGDVVIGNNDFGKYKGELQLILQDCTDERK
                     NKVGRIKEDEIILLDFIEPWSKFKIILEGE"
     gene            53666..54799
                     /locus_tag="PC494_000702"
     CDS             53666..54799
                     /locus_tag="PC494_000702"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase/deacetylase family
                     metallohydrolase"
                     /protein_id="HDF3911224.1"
                     /translation="MKIDILIKCGKTVDKSIIDIAILDDKIIEVKNQIDDSKYQAKQI
                     INLDGEKFISAGWIDIHTHCYERLDLYKDYPDEVGIKSGVTTVVDAGTTGALDIGKFY
                     EDTKKYKTNVYALINIAKQGITSQDELSSMMNIDEYELKRAVKKYKDFVVGIKARMSK
                     SVVISNDVEPLKVAKRIKNELNLPMMVHFGSSPPTIEDIFDYMEKGDILTHIYNGKPN
                     GILRGNEVKKEIIEARERGIILDVGHGTESFSMDIAMKSKDAGIFPDTISTDIYIKNR
                     INGPVYNLSTTMEKFIYMGYSLEDIINKVTKNAADAISLKNKGLIKEGYDADLTIFDV
                     VNEEKELQDSLNKSVITSTSIKPRAVVVNGEYLNIGKSIEENE"
     gene            54817..55926
                     /locus_tag="PC494_000703"
     CDS             54817..55926
                     /locus_tag="PC494_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DgaE family pyridoxal phosphate-dependent
                     ammonia lyase"
                     /protein_id="HDF3911225.1"
                     /translation="MSSIFEKYSVRRVINASGKMTILGVSTVDKEVIEAIGEGCKNFF
                     IIEELINKTGEYIANLLGCESALIVSSASAGIAQSVGAMIAKDDMSLVYNVNNPKKQV
                     KREIIIPKGHNVDYGVPVEVMIRLGGGEVVEAGYANMCNKEHIIREINENTAAIMYIK
                     SHHCVQKSMLSVLDVVQVAKEYNLPLIVDAAAEEDLNVYYELGADLVIYSGAKAIEGP
                     SSGLVIGKKKYIDNVKLQSKGIGRAMKIGKENIVGLTCAIERYISNDKVTLKEMEDKL
                     NPFIDKINTIKGVSASITRDSAGREILRGEIDFNEDIINKSTQQIINELRSGEIAIYT
                     RDYKANEGKIEIDIRSVTGSDLDTIYNRIKNIVES"
     gene            55991..56731
                     /locus_tag="PC494_000704"
     CDS             55991..56731
                     /locus_tag="PC494_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KDGP aldolase family protein"
                     /protein_id="HDF3911226.1"
                     /translation="MNCIPQYYKNRVCLNVLAGSIKNAKEVYDACDGHVLIGVLSKNY
                     STVEAAIEDMKKYSKEIDNAISVGLGAGDPNQSNMVSQISKELQPQHINQVFTGVATS
                     RALLGQNDSIINGLVSPTGKPGFVKISTGPLSSKEKDGIVPIETAIAMMKDMGGSSIK
                     FFPMGGLKTKDEYIEVAKACAKHNFYLEPTGGIDLDNFKEIVQIALDAGVEKVIPHVY
                     TSIIDKETGETKVEDIGVLYKIMKELLG"
     gene            56736..57728
                     /locus_tag="PC494_000705"
     CDS             56736..57728
                     /locus_tag="PC494_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HDF3911227.1"
                     /translation="MNILAFGEIMMRLSVPDYKFLTQTNELNYIITGTGLNILSGLKN
                     FGYNTYMLTKLPNNNVGKALSANIRKLGVKDDFITYGGNHIGVYFLENGYGERPSEVT
                     YLNRLNSSFCESKLQDYDIDKCLEGMDIVHICGIAMQLTDSVKEIALELARKSYEKGI
                     KVFFDFNFRQSLNPERTYDDLVNDYKKILPYCHGLFASYRDINKILNIDSLNIKSSSE
                     LIKKEYDIGIVAGTMRRFDDMNNRFIKGYISNDDGYFESREYKLEIYDRVGAGDGYVA
                     GIIYSYLENMKSEDIVEFGVASSVLAHTTYGDNSLVSTGHVLRLMNNEKIDILR"
     gene            complement(57916..58797)
                     /locus_tag="PC494_000706"
     CDS             complement(57916..58797)
                     /locus_tag="PC494_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDF3911228.1"
                     /translation="MNTKQLEYFISVAEKLSFTKTAEKFYISQTAVTQQIKALEEQIN
                     VTLFTRSKRHVELTPAGKVFLSEARTIIKNINDAIAKTQQFAHGFFGTLSIGTLIGYE
                     KNKLQQYLKEFSNTYPNISMDICTNEITELLNLVKNNSMDLAFVINPENQPLKDFEYK
                     TVERYSLVALLPPGHPLYNEDSIDLIELQHDKFIFVKETGDEYGQKSMIQNRYREAGF
                     VPNVVQRSNNLNTIESLVSSNMGISILPSFCVTDTMIERDIAIVPIKEVENRIEVVVV
                     WNKKNTNPALEKFISII"
     gene            59071..60459
                     /locus_tag="PC494_000707"
     CDS             59071..60459
                     /locus_tag="PC494_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3911229.1"
                     /translation="MEDKFYAKGNGNNGYIKNLEVCSFNNLDGTCGMFQMALYKRDEK
                     YYLYGCCFGGNKKNGVMISDITDPYNPQFIKHFQMLDPKEYPTTTTPKIQIADDLMIV
                     AMSCGSGPGALVDQAKLANIKCEAGIRIYSLKEDPLNPKFLGYWDCGLKHVMGVHRFM
                     YNGGRYVHLSSDCVGFEGLIYRVIDIINPTNPVEIGKWWRPDQYADGYPNRTFDAGAP
                     HCPEFMDKGWLHGPPFVRDGKAYCGYGGAGLVVLDVEDLTRPRCLGELPFTPAFSSRL
                     AGARTHTALPLPGRDLVVVQNEGERFQFFKPDNITDVQAMNNIHMVDVSDPTKPTLIA
                     QFPYPEVPKDFPYPNFNVAGLGKPGPFGPHNLHEPMDNKPWLEQRGDRVYCCYFHAGL
                     RVYDVSDPYYIKELAYFIPPNPNKTPEESYFPGFPGPRLAVTEDLIVDDRGYIIIDAL
                     DDGFYILKMKED"
     gene            60487..61440
                     /locus_tag="PC494_000708"
     CDS             60487..61440
                     /locus_tag="PC494_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HDF3911230.1"
                     /translation="MKILGISFGTKNGNNDTMCKVALKGAKEAGAEVEFIQMSSINIK
                     HCTGCCACVKTLLSGKGSMCVLKDDFEWLLDKMKDADGIVVSDPIFEEGASGLFHTIM
                     DRFGPRADRGNNIIGTKVAEVIGGKIPDSRMLNDKVISFMGIGGSDWGTRVQCEHAML
                     ALIPMWKVIDNAWFPWAKELVMDDTRLVQVHQIGLNIVEAAKDFEKASYQGEEGVCPH
                     CHNRLFYLEPGTKKAICALCGIVGELDTISGKTIFSFPEEQLGHAHDTLPGKFIHGDD
                     IKKMEGHYAEVRKTQEFKERKTSYNFIEPLTKEKQAGVSLG"
     gene            61500..61724
                     /locus_tag="PC494_000709"
     CDS             61500..61724
                     /locus_tag="PC494_000709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3911231.1"
                     /translation="MNEKPSFKQIEVILAVIFLVLTYYKVRLTPAFIVIFIPLYLSYF
                     AVSMIVNQIAIKLLEIRQAREATNYNIGNG"
     gene            61717..62229
                     /locus_tag="PC494_000710"
     CDS             61717..62229
                     /locus_tag="PC494_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1097 domain-containing protein"
                     /protein_id="HDF3911232.1"
                     /translation="MDRKKKEILTLSMGIALLPPLWAVLAPYIGIKTGAVALICAGLY
                     VTNGNKQKDGLKIMFGFWCGDLWAVLAILIMGYMNFNQNLELFLTLSILGFFAVVIAS
                     LFEKIIFLPSWLCGWAIGLTVMTGENIINLQDICIQIAVAMAVGVWYVGAGVDLFTIY
                     ILSKDRKKGN"
     gene            62261..63115
                     /locus_tag="PC494_000711"
     CDS             62261..63115
                     /locus_tag="PC494_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA hydrolase"
                     /protein_id="HDF3911233.1"
                     /translation="MAMGFEFKIMRSLIYVGLAKEEYRPKLMDWLYRHHIPDSISTFG
                     PYCTKYAFYQAYPTPNEGERFGARKMQLTEHYWLVDEHMPEMANRIMTEYMPMDVLRW
                     QGCIPDVENKRVHENVESGDAGRAVGGDNGCPPFIFAFVPINWEEDFRGKGRTVQDGP
                     NYRWQFMIKYPDGISKEEGEKWFYDEVVPYFTNCCYVNRFVSSKIMINYGATAFDRVS
                     ELWFEGEEEWYKAVVEETKSFIKKPEWAQEEEFPYLKPQFNIASVFLGDIATMDAYSQ
                     YRGYIPMR"
     gene            63649..64443
                     /locus_tag="PC494_000712"
     CDS             63649..64443
                     /locus_tag="PC494_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HDF3911234.1"
                     /translation="MYTIGQVSKFLGISRDTLKFYEDKGLVNPKKNDENGYRIYNQVD
                     IYDIATINFYREIDIEIKKIQEIRKSKSINNLELLLEEKEQIILKEIEYKKLLLKKVQ
                     LVKEDCDKIKTYFGKYTIKEMKPLEVKGKIKHVTNYEEYEALKENTNNLKKAVTLTDL
                     RRVINFNEEGIIEEKFIIVREVDDYNKIIEGEVLSHPNCIYTIIEDGRWSTGGENIDN
                     KVEDRLREIAIENECELLGIVYVNILLTTYEEGIERIFLEIYAPIK"
     gene            64547..65371
                     /locus_tag="PC494_000713"
     CDS             64547..65371
                     /locus_tag="PC494_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HDF3911235.1"
                     /translation="MRTEKSLKRPIASFIILTNIIFLPLFLLVVVTIMLKLPTVISDI
                     ALCISAWSSTFAFMILFKKIYPDKKFLVHVKDRFRNKLKFSTVSIIISIQVLIAVVVI
                     FILASKNHGIMPNFTVSSWGAFIYLFLKNLFAGSLGEELGWRGFVQNHLQKRHSPLKA
                     SIIVGFWWGMWHLPIWFTTGFKGLDLIKYIIFFMIAIISISIIMTTFYNLNKTLIIPI
                     VIHQLFNFLIGIINGDLIELINYYAMLYLIVAIVLVAINPGNALYKRFSKNTTQIL"
     gene            66002..68089
                     /locus_tag="PC494_000714"
     CDS             66002..68089
                     /locus_tag="PC494_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HDF3911236.1"
                     /translation="MVVDKEIVSILQILLNSTLITTNGLQEESNSSKRQITYRINKIN
                     DMLKVKNVPLICLRADKDIIVRKETKKAIKEILEKNYSKNTYYFSKTERLLYMYLMLF
                     INMEDISINHFINSIKVSRSTVNLDFKDLIPKLEKKNIKVKNNRINGYYIVGNEMEIR
                     RVLIKNIIETLSNEKSSRVFDIFIKEYNLDSFEEAKKIILKLIKKYEITFVEDRLIEF
                     IYIFIFLKARMYSTRIVTQENVDIPNISVMSSMKEYKFAKELLEVYGSEDKIKPHNIM
                     YISAWILGISVGNYEEDTEDKDVISKIVNKMMTKFGYLSGVYYISQEKIFKQLYSHFR
                     PAYYRLLFKLPIYNPICEKVKEEYKLVYRIVSNAMKEFCGLFGEEIQEEELAYLTMHF
                     ATLFSNKKEFDGFRKRIALIVCSNGVGSSAILHAELTNLFPDLHFIPMSESVGLENIS
                     EPVDIVFTTNYNAEGLKTDVPVIKVSPVMTTKEKYKITREVYIQLGDIFLRQPKIDEV
                     MDIIKKYANVTSESILSSELLAYFTQIENFTSKEGEGPMLSEITNETLVKIKVKAKNW
                     EEAIRQSASVLVENNKVTEGYVDAMINSAKASGPYIVITKHVALPHARPEAGSKEIAI
                     GIATLDSPIEFGNNENDPVKYVFCLSAIDNNSHLRAMSELVELLEEDEFFKVLDSAKE
                     AKEIIDFIKTHEL"
     gene            68104..68391
                     /locus_tag="PC494_000715"
     CDS             68104..68391
                     /locus_tag="PC494_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDF3911237.1"
                     /translation="MYKILIACRAGVGSSLMLKIKTQQIIKENNFPIEVEHGSLDSLN
                     GFNGDAVETLIDVAEELKNKNLKFDIIGIHNIVDRNEIKTALEKFLASKEG"
     gene            68418..69689
                     /locus_tag="PC494_000716"
     CDS             68418..69689
                     /locus_tag="PC494_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit IIC"
                     /protein_id="HDF3911238.1"
                     /translation="MEFIISLLSTPAVLLGVVACIGLILQKKSAVEVFTGSSKTLIGF
                     LIFGIGASAMTGALQNFNKLFQHGFGITGVIASPEAATALAQGTYGFAVSCTLILGFI
                     LNLVFARITKFKNIFFTTGHSLFFSCVLVLIMKAHGFDNTITILIGGTILGFMSAALP
                     QFCQPFMRELTGGDEQAIGHFNMIGYGLSGYIGRLFSKHKDDTTETIEFPKWLSIFRD
                     FLMGLSIVMLILFYIATLKAGQAFTQEIAGSTHWLVFPLIEAFTFVAGMSILMSGVRM
                     FLAEITAAFVIISEKYIPGSRPALDVPTVFPYAPNAVIIGFISAYAAGLLAIAIMASF
                     PSIFPVVIIPAAHICFFSGGTAAIFGNTSGGWRGAIAGSFVVGLLLAFLPVILYPVYG
                     TLGIEGATFPNIDYNVVGSILHNILQFIKPI"
     gene            69747..70346
                     /locus_tag="PC494_000717"
     CDS             69747..70346
                     /locus_tag="PC494_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HDF3911239.1"
                     /translation="MENTLSEFLDNISNELSEFIASIDETSINKACELILEAEKNHGR
                     VHVTGIGKPGHVSGYISSLLSSTGTSAYILHGTEAVHGSSGQVVEGDVVIAISNSGET
                     QELKATLKTLKVNGAKIIGVSGNESSFLKNISDIFLFAGVKQEGDCLNKAPRASILAE
                     TIILQSLSVVLQYAKGLNTQQYLKWHPAGSLGKSIREGI"
     gene            70351..71256
                     /gene="dapA"
                     /locus_tag="PC494_000718"
     CDS             70351..71256
                     /gene="dapA"
                     /locus_tag="PC494_000718"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HDF3911240.1"
                     /translation="MKYKGIICAMITPFDENQNINSQATCQLIDYLIEKGIYGLFILG
                     TNGECHVLTDDEKVEFAKIVINHTNNRVPVFVGTGGNSTREVVDLSKRMEAIGASALS
                     IITPYFVTPTQQELILHYKTIANSVNLPIIMYNMPGKTGINIEPESVRELSKIKNIVG
                     IKDSSGKLDNMKAYIEATKNENFSVFSGSDSLILDSLKAGSQGAVAATTNFLTEIGIS
                     IYENFMKGDLEEAQKAQSSIEELRRILKLGTIPSVMKKTIVLNGINVGTARLPVTEPT
                     GEVLEEIKRVVENYRTILNKSSENR"
     gene            71362..71994
                     /locus_tag="PC494_000719"
     CDS             71362..71994
                     /locus_tag="PC494_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketohydroxyglutarate aldolase"
                     /protein_id="HDF3911241.1"
                     /translation="MKKMNITKRMSECGALAIVREENLNRACEIAEGCIKGGITVIEM
                     SYTLNNAGEIIQGLNKKYGETLCVGAGTVLDSETARHAILHGAQFIIAPNYNEGVAKI
                     CNRYQIPYAPGCTSLTEAVDALSLGATFIKAFPISDFYGPKLVKVFKTPIPDMPVLAS
                     GGINIENLHIWLENGVDVCGFGGLLTKGSVEDIAKNAKKIREIIKNVKKI"
     gene            72472..74979
                     /locus_tag="PC494_000720"
     CDS             72472..74979
                     /locus_tag="PC494_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HDF3911242.1"
                     /translation="MKEDIGLHRMCKKEQATKNEVISEDILKSMSIGVSKHFLDDSFT
                     IIWGNTSFYQLLGYTEEEFLVKFSSLKDYYEQNLYHFESMKNHFLEAYHHGEKSIEYQ
                     ICISANNGDPVWVIMTGILIESQDNEKSMVYILYSKINELKIKQEELSDMEKESTENF
                     KWMMSEYAGNVYISDMDTYELLYLNKHSCNTLQASANELIGRKCYEVIQGRTSPCPFC
                     TNSYLKKDDTYEWEFYNKKLKRTFIIKDRMLNWQGRRVRIELSYDMYSAEYKLAKKDQ
                     ERESILKTIPAGMVRLDARDYLTILWCNDIFLNMIEYTKEQFAEELNNQCGYLFSEDY
                     KRSKKLAQDLKESGDNIVFEAKIYTRSREERIWTVTLCYISGEDSWDGIPSFYSIGID
                     ITKERKQIEKLQHISEKDALTGIYNRAETERQIKKYFEKNLNVMGALFMIDTDNFKQI
                     NDTEGHMIGDIVLTEMASGMKKIMRDSDVVGRIGGDEFTIFMKNISSVKDAEKKAEEL
                     LYMFRHLFQKEKSFLKVTCSIGIAIYPKDGTTFKEIYARADKALYQAKNMGKNNYVIY
                     NQDYFKELEEFDCSSLGTVIDSEKQYAEYPDNLTRYIFRMLYQTDDIDQAINMILEVV
                     GKQFDVSRVYIFENTEDGRYTSNTYEWCNEGISSQMAYLQNSNYQDYEDYEKLFEDEL
                     VFYCRDIHTLSPKLEELFSSQGIHSTLQCAYKEDRVFSGFVGFDECTGLRLWSQEEIS
                     TLSLISQIISMFLQRKKNNKLNQQIQQYQNILDNIDQCICVINKENNFLLYVNKKFKN
                     TYSKFQIGQPYYLDSIDIHKISIIWNKKEAYLCTSMI"
     gene            75321..77483
                     /locus_tag="PC494_000721"
     CDS             75321..77483
                     /locus_tag="PC494_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1430 domain-containing protein"
                     /protein_id="HDF3911243.1"
                     /translation="MKKIIYVLFTIELLIVSLLGLNIVKDNEINNILYNDTTSISVMF
                     KDYKRLNKNYSKWIKDIADENNVTISKYVFNNNEKLSIYTTDTSLNNNIKLKSGKFPN
                     TNSNEFISNINTNNSNQVGKFSTMSKDISILIRDFGKISEVGESGILYISTQNEDTIN
                     KILKELNVDRSIFIARLHDRYVNSNLYLNPSIIRDLILIILCFLATIIHYSISVSREA
                     SILRLNGYSKLDIIARVIKNILRIMILSSVTALLIYIIYILKLNIGVRACLYFAMFSI
                     ICILINILISILIVGFNSRSSKYMLSLNGKKSYGFVNIMHFTLKIVFISFLILSINNC
                     ILNYNMLQTQLGNLSEWDKAKNVYNLTLKDTGEQSLGKEEVIKNAKIKGFYKNLVEEK
                     DAFLIDSTNFEKLEDGSYMYEINSKGKNPEVSQYGKNIKINKNYLKVNPIYSNGKEIF
                     NLIDYDDKTINLLVPKKLQVHENEIKKEFRELFYFEKIEVENMYNKELNRELNKTKKS
                     DLNVNIIYVDNNQSYFTYNSLVMDDNRNLIDDPIAIVDIDNIDDSFYLSYISRCVYFN
                     SKKLDALADISNIIEAQGVEAHIQSLHAVYNEYGLEINKLEKYLNSEIFTIIIIAISN
                     LMITYNIVASYYERNKYKLYIKKIFGYSATARSMLLIVSLILTNIIPIGIISTRVDLS
                     NNIILFGLLILVIEVIVSIVLDKIISNSSFNKIIKGEH"
     gene            77488..78105
                     /locus_tag="PC494_000722"
     CDS             77488..78105
                     /locus_tag="PC494_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF3911244.1"
                     /translation="MISLINISKKFKDKSIIDKFNLEISKGEFVAITGNSGSGKTTLL
                     NIMGLLEKPNSGDIIINNIKNPNSKQIRILQRDFYGYLFQNYALIENENVENNLKIAL
                     KYQKNINHNEKINYALESVGLRKYNKKKIYELSGGEQQRVALARVILKECEVIFADEP
                     TGNLDKKNRDIVFDILKSLNKNGKTIVFVTHDLELSEQADRVIKL"
     gene            78294..78638
                     /locus_tag="PC494_000723"
     CDS             78294..78638
                     /locus_tag="PC494_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000212737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkylphosphonate utilization protein"
                     /protein_id="HDF3911245.1"
                     /translation="MENLPNCPKCNSEYTYEDGTLLVCPECSHEWALGLGAEEDSNII
                     KDVNGNVLNDGDSVTVIRDLKVKGSSSSIKIGTKVKNIRLIHDSSDGHDIECKIDGFG
                     AMKLKSSVVKKA"
     gene            79208..80074
                     /locus_tag="PC494_000724"
     CDS             79208..80074
                     /locus_tag="PC494_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HDF3911246.1"
                     /translation="MIDIHKNIYDNKLFEELKIDCKKCFGLCCVALYFSASDGFPIDK
                     ESGKPCINLQPDFKCSVHNSLMKRGFKGCTAYDCFGSGQKVAQVTYKGIDWMQSPELT
                     NQMSEVFLIMRQLHEMLWYLKEASVLNISDTIKSKIDLIIEETEKITNMGPEQIINLD
                     IISHRTKVNLLLSQASESVMGKVKSFIKTSTLKNMKKLSKNIDLIGADLRKINLIGAD
                     LRGRFLIAANLRNTDLSGANLIGADLRDCDIRGANLENSIFLTQLQVNTAKGDSSTKL
                     PASLIRPKYWEK"
     gene            80187..80591
                     /locus_tag="PC494_000725"
     CDS             80187..80591
                     /locus_tag="PC494_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YmaF family protein"
                     /protein_id="HDF3911247.1"
                     /translation="MSYQNYKCERDYVYDDYKYNKCNKCYNDYEEMTHVHEYSESVKL
                     AEECEDRHNHRAAGVTGEAIPINGGTNHVHKINDNVDFLDHFHKICVTTGPAIRIPGT
                     DKHIHLICGETTVNDGHCHKFLFTTQIEAPLV"
     gene            80755..81204
                     /locus_tag="PC494_000726"
     CDS             80755..81204
                     /locus_tag="PC494_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDF3911248.1"
                     /translation="MKSGIILEMKQINSTEYDEMLQVWESSVRATHDFLTEKDIESLI
                     PLVEIGLKEVENIVCIKDNDIIKGFIGIDKDKIEMLFIEDKYRGNGIGKKLIKYAIDK
                     YNVKYVDVNEQNKKAVGFYIHLGFKVFDRSEIDGQGNPFPILHMKLI"
     gene            complement(81360..81737)
                     /locus_tag="PC494_000727"
     CDS             complement(81360..81737)
                     /locus_tag="PC494_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HDF3911249.1"
                     /translation="MLTPYLIFNGTCEKAFNFYAEAFGGGKTIFARLDSNPNNPIMHA
                     SVTFTKYEGCIMGADTDKPVVISGMAICVVLPSREAIEEISVKLAEGGTLVQEFLPHP
                     PPHQNDGAAEVLDRYGYTWYLST"
     gene            81999..82916
                     /locus_tag="PC494_000728"
     CDS             81999..82916
                     /locus_tag="PC494_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2268 domain-containing protein"
                     /protein_id="HDF3911250.1"
                     /translation="MVNMNIIEIRSDKIYKKIMDAPINKKEDIYRYELMKPFEFKWKC
                     MNVPIVARQKGGYDVIIASEMLGVLSPKDIDEKQKKNINVLSADKIWGTCKETIENSI
                     NAFIKEGYDLNIKDYKYSILLANPNSPYTILSDGYWGDGGIPGYIFLSLVPNEYTINR
                     LPVLIAHECNHNIRFQFIEWNNNITLEEMMINEGLAENFATWMFGEEMLGPWVSRTDI
                     ETLNTYIKPIIKSALKETGFRNITSYLYGDDIAKMQGYFPVGLPYCAGYACGYYMIKY
                     YLEKTNKSIIEATLLPYSEIIEAVKEFWE"
BASE COUNT        32091 a         9671 c        13800 g        27629 t
ORIGIN      
        1 atataaatta acctactgtt taattttcaa tgttcgtgtt tatttcttgt tccttttttc
       61 aaggacaagt aatactatac catctttaaa acagtaggtc aatacttttt ttatattttt
      121 ttataaattt ttttcatatt cttttttcag cttctctact acctttttct ctagtctaga
      181 aacagtcatc tgtgatatcc ctagttcttt agctatacta gattgtgttt tatcaaagaa
      241 aaatctatct ttaaaaattt taacttctaa ttcatttaaa gtttcaataa acttattaat
      301 aaaatcttca tactctatac ttccaaagtt accttcttct tttccaatct tatcaataag
      361 agttatatct ttatcctctg aatcatcatt acttgatgaa tccaaagaca ttggttgata
      421 tccataagaa gcctccatag cctctaaaac atcttcttca ctaacgccta tataatcagc
      481 tatatctttt acctttggat gcttcttatt ttcttgttct aatttaatct tcgcatcact
      541 tatctttttg cttaattcct gtattcttct tgggactcta agtgtccata ccttatctct
      601 aaaatacttt tttatttctc ctactatagt tggtgttgca aagctggaga actcaaatcc
      661 tttctcaaca tcatatctat caatagcata aattaatgcc aatgaagcaa cttgatatat
      721 atcttcaaaa tcaacacctt tgtttatata cttcttagct aacaatcttg ctaaatacag
      781 atgtctttca ataagaatat ttctaatgtc tacattttta tttttattat ataaattaaa
      841 tagctctttt gtatccatat ttaggtaatg tgtagcatta gctacatttt tcattaaata
      901 tcaactccta aatatttagt catttttatt tttgtccctt gattatgttc tgattcaata
      961 tctacatcat ccattaaagt tttaattata aacaatccaa gaccactctc ttttggattc
     1021 tctaaatctg gtgtacttat tgagctaaca tcatatcctt ttccattatc ttgaatttct
     1081 atattaattg cattatctaa aatattaaat actatattaa acacatcatc tttactgtgt
     1141 tttattgcat ttgtgcatgc ttcagatact gctaccttta tatcttctat atcatctatt
     1201 ggaaaaccca tcttattggc aattccagat gctgttaatc ttattatact aacataatct
     1261 ggatttgtag taatttccat ctttatagtc tcacaagcca aagtttatcc ctccacttta
     1321 aatattttat ctagacctgt tatagtaaaa atctttctta cgttactctt aggatttact
     1381 atgtatatct ctttttcatt tatttttaat ttttttaata cacctatcat agctcctaag
     1441 cctgttgagt ctatataatc taaatcttta agattaatct ttacatctaa catatttttt
     1501 tctattaaag catgtaaatg ttcctttagt ttatctgctg tagaaacatc aagttctcca
     1561 tcaagacaaa cattccaaaa tttattttgt gaatctaaat ttgaatcaat attcatagac
     1621 atgtaaaaac ctcctatttc cttttaataa ttttaaatat atttcctata ctcaatattt
     1681 tattaattac ataaactata tcatctattc cctttgatat tgatgatgca ttttcaacaa
     1741 tatcttgtat atgtctttca ttataatcta caatcttata tgccttttca acaaccttat
     1801 ttatgctgtt tagagtttta gctaaataaa ttgctactat aagagcagag cttcctacta
     1861 acactgctcc aatttgccac ccccatgcat tcattagtta acatctccct catcatcaaa
     1921 gcttttactt attactatat cttcttctga aatctttata tcttcttcat tattatcatc
     1981 atccactaaa tttattattc tctctttaac atcattaaat gtttcatgta gaacttcttt
     2041 tgggttttct ttgacatcat taaacttctc ttttgtttct tttcttagtt cagaaccttt
     2101 tttaggtgca aaaaacatac caaatataaa ccctaaaata gctcctaata ataaaaatcc
     2161 acctttttta caacttcttt tattgcacat aacaattact cctttcaatt ttaaattttt
     2221 atctaactac attatacaaa aagaatagga tatttatcct attcttcttc aatatttatt
     2281 ttggcaatcg aaactacatt gacttcatca ttcgtcttca ttaatttaac accacttgta
     2341 actcttccaa acagtgatat ttcattgact cttattctaa taagaactcc atcagaattt
     2401 ataatcatta tctcatcatc ttcgttgacc atatctgcac ctacaattgt accagttttt
     2461 tcagatatat tataagtttt aattccttta ccagctctta tttgacttct atactcttct
     2521 atatttgttc tctttccaaa accattctta cttacaacta acacatctgt acctttactg
     2581 caaaggttca tagacacaac aaaatcttct ttacttaaag ttataccttt tacacccatt
     2641 gctgttctac ccatatatct tatatcattt tcatcaaatc ttatagacat accttcttta
     2701 gttactaaaa gtacttcttg ttttccatct gtaagttcta ctccaataag ctcatcatca
     2761 tctcttaaac ctattgcaat aagaccagat ttatttatat ttttgaactc ttctctctta
     2821 gtctttttaa caataccttt tttcgttgca agtaataaat attcattttc atcattacca
     2881 tcaataggta ttagagtagc aattttctca tctgctgaca attgaagtaa attcactata
     2941 gcagtacctt tagcctgtct cttaccttct ggtatttcat atgcatttaa tttaaatact
     3001 ctacctttat ttgtaaagaa taatagtcta ctatgagtag ttgtagttac caagtgcctt
     3061 acaaaatctt cttctctagt tgtaagtgct gaaatacctc ttccacccct tttttgactc
     3121 ttataagtat cagatggaag cctttttata tatccaaagt gagtaagagt tattgctatt
     3181 tcttcatcac ttataagatc tctcatatct atttcgcctt cagcatgtct tatttctgtt
     3241 cttctctcat cagagtaatt ttcttttatt attgtaattt catcctttat tacatttaaa
     3301 agtaatcttt catcagctaa aatctctttt aatctattta tcttcttgat taaatcttca
     3361 tattcagctt ctatcttatc tctttctaaa cctgtaagtc tttgaagtct catatctaat
     3421 atagcttgtg cttggatttc agttaatttg aatttttcta ttaaacctag cttagcttct
     3481 tgcccagtct ttgaagctct tatcaagctt ataacagcat ctatattatc taaagcaatc
     3541 tttaatcctt ctaaaatatg tgctcttgct tcagctttat ttagttcaaa tttagttctt
     3601 cttgtaacaa catcttcttg atgtttaata taatgatata atatttgttt aagatttaaa
     3661 actcttggct gaccatctac aagtgcaagc attattatac taaaagtatc ttccatttga
     3721 gaatgtttat acaaattatt taatactata ttagcattag catccctctt taattctata
     3781 acaattctca taccatttct attactttcg tctcttaggt ctgatatacc ttctattctc
     3841 ttttctttaa ctaactctgc tattctttca acgagtttag ccttatttac ttgataaggt
     3901 atttctgtaa ctattatttg ctgttttcct tttggtagct cttctataaa agctctagac
     3961 ctaactttaa cttttcctct tccagttctg tatgcttctg ctatactttc ttttcccatt
     4021 ataattgcag ctgtagggaa atctggtcct tgaacaaatt ttattaaatc atctacacta
     4081 cactctggat tatctatcaa atatacagtt gcatcaatta cttctgctaa attatgtgga
     4141 ggtattgaag ttgccatacc aacagctata ccatttgagc catttactaa taaattagga
     4201 tatctagctg gcaatactga aggctctttt aacgactcat caaagtttgg tttaaagtct
     4261 acagtttcct tttcaatatc tctcagtagt tctaatgata atttactcat tttagcttct
     4321 gtataacgca tagcagctgg tgaatcccca tcaacagaac caaagttacc atgaccatct
     4381 actaaaagtg ctctagttga aaaatcttgt gccattctta ccatagcata ataaacagca
     4441 gtatctccat gaggatggta cttacctaaa acgtccccaa caatacgagc tgacttccta
     4501 tatggtttat ctggagttaa atttaactca ctcattgaat ataatattct tctatgaact
     4561 ggctttaaac catctctaac atcaggaaga gcacgtccag ctataacact cattgaataa
     4621 tcaatatacg attttttcat ttcttccgct atttcaatag ggagtatttt gttattttct
     4681 tccatgtata ctaatcccct ctctctatat atctaagttt ctaacaaatc ttgcattttc
     4741 ttctataaat tcttttcttg gagcaacctt atcacccata agcattgaaa atacttcatc
     4801 tgcaattgca gcatcttcta cagtaacttg taataaagtt cttgtctcag gattcatagt
     4861 tgtttcccat aattgctctg cattcatctc tccaagacct ttgtaccttt gaagttcaac
     4921 accatttctt ccaatttcat ctaataaaat atttaactct ttatctgagt aaacataatg
     4981 ttccttcttt tgctttgtca ctttatataa aggtggctgt gctgcataaa catacccctc
     5041 atctataaga ggtctcatat atctaaagaa gaatgttaat aataaagttc ttatatgggc
     5101 tccgtctaca tcagcatcgg tcataattat aattttatga tacctagcct tatctatatc
     5161 aaaatcttct ccaataccac aaccataagc tgttatcata ttttttattt catctgaaga
     5221 tagtatccta tctagtcttg atttctcaac attaagtatt ttccctctta atggaagtat
     5281 agcttgacta tttctatctc taccttgttt agctgaacct cccgctgaat ccccttcgac
     5341 taagaatatt tcacttttag atggatcttt ttctgcacaa tctgcaagtt ttccaggtaa
     5401 agatgtactt tctaatacac tttttctcct tgttaattct cttgcttttt ttgcagcttc
     5461 tctagctctt tgtgctctta aagctttatc aactatgatt cttgctgttg atgggttttc
     5521 ctctaggaaa gaccccagtt catcaactgt tacactatca actatacctc tcataaagct
     5581 attacctagc tttgttttag tttgaccttc aaattgaggt tctggtaatt taactgatac
     5641 tactgctgta agaccttctc ttatgtcttc accaagtagg ttaacatcat tttcctttaa
     5701 aaatttattt ctcttagcat aatcatttac agttttagta agagctgctt taaatccact
     5761 taaatgagaa ccaccttcgt gtgtatttat attgtttgca aaagaatata tgttctctgt
     5821 ataaccatct gtatattgca tagctagttc aacaaaacaa tcatcaacct ttttatctat
     5881 ataaactatg tcatcatgta taccagttct agatttattt aaatacttaa tgtattctac
     5941 caaaccacct gtatagtgaa attcttttct tttttcttgt ccttctcttt tatcttcaaa
     6001 tactattttt attcctttat tcaagaaaga aagttctcta agcctatact ccaatgtttc
     6061 atatttaaac tctatttcat caaatattgt ctcatctggc ataaattgaa tcattgttcc
     6121 tttatcttga gattctccaa ctacttcaag cttagatgtt ggcaatcctt tctcatatgt
     6181 ctgcttatat atctttccgt ttaaataaac ctctgctacc atccattttg acaatgcatt
     6241 aactacagaa acaccaactc catgaagacc tccagatact ttatatcctc cgcctccaaa
     6301 ctttcctcct gcatgaagat tagttaatac tgtttctaaa gttgatttac cagttttagg
     6361 atgtatttca acaggtatac ctcttccgtt atcttttact aaaacactgc catcttcatt
     6421 aatagataca tatatgtctg aacaatatcc ttgtaaagcc tcatctatac tattatctac
     6481 aacttcataa actaagtgat gtaaacctct agggcttgta ctaccaatat acatacctgg
     6541 tctttttcta acggcttcta atccctctaa tacttgtatc tgacttgcac cgtattcttg
     6601 tttcatttaa tttcctccat tctctatgct aataacatcg ccattttcaa tattaaatat
     6661 tgtaacattt ttttcatcaa atattttttt atgtgaaact tcagcacttg ttataaacat
     6721 ttgaacattg cttaaattat ttactaaaag tttttgtctt gcttcatcta actcactaaa
     6781 aacatcatct aaaattaata ctggatattc ttcaacttca ttttttatta attctatctc
     6841 tgataacttt aatgatattg aagcagttct ttgttgacct tgtgaaccaa aaagtcttgc
     6901 atctaaatca tttatgaata tatttaagtc atctttgtgt ataccatatc tggtagtctt
     6961 agattctata tcattaggtc tattcgatga caacttggct aaaaatttat tatatactgt
     7021 atctatagta tcttcatcag ttatatttat ttgattttta tatcgaattg ataatctttc
     7081 aactccatta gtcaaattca tatgcatatt ttcagatata ttagctatct tttttataaa
     7141 gtctctacgc aaaatataaa tataacttcc atactttgct aacgtatcat catatacatc
     7201 taataaagct tcatcaacat gtatattttt aagcacccta ctcctttgag aaagtgtttt
     7261 attataattg gtaagatatt tataatattt aggtataatc tgactaatct ctttgtctat
     7321 aaatgccctt ctttctttag gaccctcttt aaccaacctt aaatcctcag gagaaaatat
     7381 aacaacattt aagttgccaa gtagctcttg tatcttttgt aaaggaactt tatttattct
     7441 tatccctttt ttatcttttc caataattag ctctattaga ctatatttat tatattttga
     7501 aaaacttcct ccaatatata agttttcact attaaatcta accatttctt tatctttgtt
     7561 agtcctaaat gattttccaa aagaaagcat ataaatagat tctactatat ttgtctttcc
     7621 ttgaccattt ttaccaacaa gtagatttac tttcccatta aattccagat gcaacttttt
     7681 ataatttcta aaattaacaa gttgcaaact tttaagtttc acaaaaagtt ctcctttttt
     7741 tacaatactt ttattttagt tccttctatt tcaactatat ctcctgattt tatctttttt
     7801 cctcttctta attctatttc atcatttact gtcactaaac cttcttgaat taaaaatttt
     7861 gcatgacctc ctgttgatgc aatctctgct aatttaagaa attgatccaa ctttatatat
     7921 tctgattcta tagttatttc agtcataata gttcctcctt gtcactattt taaacaaatt
     7981 cctattgata cactaaaagt atattatacc ataaatatgc ttataaaagg agttgtctaa
     8041 gattagaaaa attttctaca aaagacaact ccttcatgtc tgctatatat ttgatgatat
     8101 tcttactgga agcagtaagt aaatataatt aacatcatct gttggtttaa ttatacaagg
     8161 atttacattt gtagtaaatt ctataaatat ttcctcatta tctatatttt tcaaaccttc
     8221 gataaaatat ctagaattga aagctatatc taggtaatct ccatctaaat ctatttcaac
     8281 ttcttcatac acatttcctt tttctgtatt agaagtaatt gccattactt tatctcttat
     8341 agataacttt ataagattat ttttttctga ttgagacaat aaagacgctc tctctatact
     8401 atttaaaagt tccttagtat ttaatttaac tctgctgtta tgttctcttg gcaataattt
     8461 tttataatca ataaaatctc cttcaagcaa tcttgtaata attttcgtat cattaattat
     8521 aaaaatagca tttttttcgt taaatccaac tttaacatta tcctctccag aaagcaaact
     8581 atttacatct ataagtgtct ttccaggaat tatgactttt atattttcag ttaaactatc
     8641 aaccgaacaa ctttttacag ctaatctata tccatcaatt gctactaaat ttaagtttct
     8701 atctacaatt tctaaaagtt ctcccattaa aacaggtttt gtttggtcct gtgagatagc
     8761 aaatacagtt tgtttaatca tattttttag gatttcttga ggtatgctat ataaatcttc
     8821 ttcatttaat tctggtaatt taggaaattc ttttgctgca taacctttaa ttttaaatct
     8881 tgaatttaca caatttatgt aaatattatt ttctgaatca gtttctatct caacaaagga
     8941 atctggtaat tttctaatta tatctccaaa tagccttgca tctacaacaa catcaccttt
     9001 ttctatgatt tctgcttgta cataagtttc tattcctatt tcagcatcat atccagtaag
     9061 ttttaattga ccttcttctg tagatataag tatacctttt aataattcta ttgttgtttt
     9121 tccattaata gctttttgag caattccaat tctatttgct aggatttttt gattacaaat
     9181 tattttcaat gtggataacc tcctctggct ttttatatat aaaaataagt taaaatcata
     9241 gtagtaatag tagtaggtgt tgttgataat gttaataagt atgtataaca ttataaatac
     9301 aaagatatta acatgtgtat aagatgttaa tatctttgtt attttagact tgataatttg
     9361 ttaataattt ttgttcaaaa aaagtattaa caggttattc aagagatata aacatacaat
     9421 tgtgtataaa ttatcccttc aaatctgata taattttgtc tattttagtc ttaatttctt
     9481 cactttcttc tatatcctta gatactttgt catgagcatg aattactgtt gtatggtctc
     9541 tacccccaaa ctcttcacct attttaggaa gggataaatc agtaagctcg cgcgttaaat
     9601 acatagctat ctgtcttgga taagctattg aacgtgttct ttttttagaa ttaaaatctt
     9661 ccatctttaa attgaataca gaagatactt tttcttttat tctgagaaca tttatttctt
     9721 catttttaga agttgttata atatctttta aagcttctgt agcaagatca aaagatatta
     9781 ccctattgct aagagaagaa taagcaacca ctctagttaa tgcaccttct agttccctta
     9841 tgtttgactt aatatttttt gctatatatg acataacctc atttggcaca tctatacgtt
     9901 ctagttgagc cttttttcta agtatagcaa ttcttgtctc aaagtcaggt gcttgaatat
     9961 cagttataag tcccatttca aatctcgatc ttagcctatc ttctagtgta ggtatgtctt
    10021 ttggcggtct atcactagat ataattattt gtttgtttgc ttcatgaaga gtattgaatg
    10081 tatggaaaaa ctcttcttga gttctttctt ttcctgctat aaattgaata tcgtcgatta
    10141 gtaatacatc tacgtttcta tatttattcc taaattcttc gtttttatcg tcttttatag
    10201 agtttataag ttcattagta aatttttctg aagaaacgta aactactttt gagtcttttt
    10261 tttgactaac aatatgatga cctatagcat gcattaggtg agtcttacct aatccaactc
    10321 ctccatacaa aaaaagtggg ttataagctt tagctggaga ttctgcaact gcaacgcatg
    10381 cagcatgtgc aaatctattg ctattaccaa taacgaatgt atcaaatgtg tattttggat
    10441 ttagattggg gtaaagaact ctataattta aatctgtgct atcagaattt aaatcagcaa
    10501 cctctttttc gctcaataca aatttaatat tatatttttt taatgacagt tgactaatag
    10561 catcttcaat taaatgtaaa tatctattct ctaagatatc tttattaaaa tcactaggag
    10621 ccagtaagat taaatcatta agatgtattt ttaatggtac gatgttttta aaaaaggtat
    10681 taaaacttac tgaagttaag tcacctttta ttaattgtag ggttttgtcc cataaagaaa
    10741 ctatatccat aatataaacc tccgaacaga ataattaata ttttccacaa agttattaac
    10801 agaaaagcaa aaatatatat aaattttaca gaataactaa atttatggat aatggtgttg
    10861 ataaattaat aatagtataa attattaaaa aaatatgaaa agatataaac aatatgtaga
    10921 taaagttata aataacataa acatacaata aatggtgatt ataactagag tattgtcagt
    10981 aatcttaaaa gttatacaca aaagtatcca caagctgtga ataatttcta ataagttgat
    11041 aacatttatg cacattatca acaagtatat ttataatatc aaaatatatg tcaaacttca
    11101 atgatttgta actaatttat ccacaatatt aactaattgt tgataaaaat ataaacatgt
    11161 taaaattact ttatttgtgt atataattga aaaaaataat ttagaataaa attaaataga
    11221 tttttgctag tattttcaat aaaaaaaata cataatatat atatggtaga ttttgtgata
    11281 taagcgtccc aaaaactcgt tgacaacagt agtaaaagta tttataatta tatgtgttat
    11341 gtttactttg agggtaaagt tattattttt ataaacggaa aataaaatct gaaaggcggt
    11401 gcaaaataat gagtaaaaga acttatcaac caaaaaagag acaaagaagt aaagaacatg
    11461 gtttcagaaa aagaatgaag acgtctaacg gaagaaacgt gttaaagaga agaagagcta
    11521 aaggaagaaa tagattaact cattaattac aaaagggccg ctgcaaaggt ggcctttttg
    11581 tgtaaataat tacaattcat agctgtgttt atggaggtta actatggact ttaataggac
    11641 taaagggttg aaaaaagact ctgattttag aaaagtatat aaacacggca aatcttttgc
    11701 aaacaaatat ttagtaatat atatacttaa aaataaatca gattatagta gagtaggtat
    11761 ttctgtttca aaaaaagtag gaaaagctat tactaggaat agagtaagaa gattaataaa
    11821 agaagcctac agattaaata ttgatgaaaa aattaagcct ggatatgata tagtatttat
    11881 agcaagggta tctagtaagg atgctacttt taaagacata gacaagtcta taaaaaattt
    11941 agttaaaaga acggatattt ctatttaatt gtatgctata aatatggagg ttaatgactt
    12001 tgaataaaat aatttatata ttaaaggaaa taagtaagta tttatcgaat ttatgtattt
    12061 atttagtgag attttatcaa aagtatatat ctcccttaaa gggacctacc tgtagatttt
    12121 atccaacttg ctcacaatat tcaatagagg cgtttaagaa atatggattt gtaaaaggta
    12181 tgtatttaac gataagaaga attttaaaat gtcatccttt tcatccagga ggttacgacc
    12241 ctctaaaata aaagagagta actattagga ggtataaaaa aattgaatat aataggaaat
    12301 ttcttaggat tgattcttaa ggtaatattt gaatttgtta atcattatgg tatttctata
    12361 atacttttta cgatacttgt aaagattatt ttattaccat taacaattaa gcagactaag
    12421 tcaacaaagg caatgcaaga tatacaacct cgtataaaag agatacaaga aaaatataaa
    12481 aataagccag aaaaacaaaa tgaagaaatt gttaagttat atggagaagc taaaattaat
    12541 ccactatctg gttgtttacc tttattaata cagtttccta tattaatagg attatttagc
    12601 gttttgagag aaccagttgc tcatggcgtt tttgcaaaca aagctgcatt tttagcagct
    12661 gacaatgggt ttttatggat aaaaagctta acatcaccag attatgtatt agcagtattt
    12721 tcaggagcaa gtgcatatgt catgcaaaaa gtaatgacac caaaagatca gttacaaggc
    12781 tctatgaaag taatgacata tgtaatggca ggtatgtctt tctattgggg atttatattc
    12841 ccagcaggac ttacattgta ctggacagta agtaacttat tctcaatagc tcaatattac
    12901 ttaataatga atcctttaaa agctaaactg gctgctaact ctaaggagga aaaagttaat
    12961 gagaaaaagc ctaaaattaa taaaaagtaa gagtaaagag gaagctataa gtaaagctat
    13021 agcagagttg aatttaaaag cagaggatat agaagtagaa atacttgaaa atccaagtaa
    13081 agggttttta ggttttatag gtgctaaaga tggtacttat gaaatttttg ttatcgagag
    13141 ggaagtagat gtagctaaaa attttataga ggtaatgttg aaaaatgcaa atgttgatgc
    13201 caaagtcaat gtatctcaaa aagataattt aatcatggtt gatattgaag gcaaagaagc
    13261 tgcaagttta attggtagaa gaggggaaac tttagattct attcaatttt tgactggatt
    13321 agctcttaat aaaataaata aagattctca tacaagagta cttgtagata tagaaaatta
    13381 tagatcaaaa cgagaagaat ctttaataag atatgctaat aaagttgcta gagaagtagc
    13441 gaaaacaaga aaaactaaaa aattagatta tatgaatcca tatgagagaa gaataataca
    13501 ttcagctctt caaaatgaca aatatgtaat tacatatagt gaaggaaccg atccatatag
    13561 aagattagta attgagtgta aaagataaag tcaacctcct aaacattagg gggttttatt
    13621 ttttaatatt attaaatcat taatgattgg ttaaatgtaa atctatatgt aaaaaattat
    13681 gaattaagag gtgataaatt tgtttataga tgatacaatt gcagcaatag ctacagcacc
    13741 tggagaaggt ggtataggta tacttagaat aagtggagaa aaagctttga aggttgcaga
    13801 agaaatcttt aaatctatgt ctggaaagag tattgaagaa tacaataaga gaacattaat
    13861 atatggaaat atagtggata atgaaaatat aattgatgaa gttttattgg catatatgaa
    13921 aggaccaaat tcctatacag gagaagatgt tatagaaatt aattgccatg gtggatttat
    13981 ttcggtaaag aagatattag aattaatact atcaaaagat gttagattag cagaggctgg
    14041 tgagtttact aaaagagcat tcttaaatgg aagaatagat ttatctcaag cagaggctgt
    14101 aattgatgtt ataaaagcca aaactgatat agctcatgaa gttgctcaaa atcaattaga
    14161 aggttcttta tcaaagaaga taagagaatt gagagataaa gtcactgaga tattagctca
    14221 tgtagaagtt gctatagatt atcctgagga agatattgag catataacat atcaaactct
    14281 taaagaaaaa actgatgaac ttaaaaaaga cattaaaaaa ttatatgata cagctgaaag
    14341 tggaaaaata cttagagaag gcttaaagac ggtaattgtt gggaaaccaa atgtaggtaa
    14401 atcttcacta cttaattcta ttttaggaga gaatagagca atagttactg atataccagg
    14461 aactactaga gatgttatag aagagtttgt aaacataaaa ggtatacctt taaaaattgt
    14521 tgacacagca ggtataagag atactgatga tattgttgaa aaaataggtg ttgaaaagtc
    14581 taaagaatca tttactagtg cagatttgat agtaatggtt ttagatgcat ctagaaagtt
    14641 gtcagaagaa gatatagaga tattagaaaa acttaaggat aaacaaacaa tagtgctgtt
    14701 aaataagaat gatttgaaac aagagattga agaagaaaaa atacttaaat atgtagaaaa
    14761 taatagtata ataaaaatat cagctttaca acaagaagga atagaagaat tgcaagataa
    14821 aatagagtct atggtatata aaggtagtat caaaaataat tctagtttag tagtaacaaa
    14881 ttcaagacat aaagatgcac ttagtaaagc atataaatct gcaacagatg ctttaattgc
    14941 tttggaacaa agtatgccat ttgactttgt agaagtcgat ttaaaaaata tatgggacta
    15001 tcttggatat attaatggtg atacagtaac agaggattta ctagataata tattccataa
    15061 tttctgtatt ggtaagtaat gtacaaaagt aaacttgttt ttattataga gatttttaaa
    15121 aaatttgaag tgtttctcat gaaacattaa ttttgaaaag aaaggaatta taaatgataa
    15181 agtttgaagc aggaaaatat gatgttatag tagtcggagc aggacatgct ggatgtgaag
    15241 ctgctttggc tactgcaaga atgggatata aaactttgat aataacaatg tctttggatt
    15301 ccatagcatt aatgccttgt aatccatcaa ttggagggac tggtaaaggt caattagtta
    15361 aagaaataga tgccttaggc ggtcagatgg gattaaatat agacaagaca tatatacaaa
    15421 gtagaatgtt aaatactgcc aaaggtccag cggtacactc tttaagagca caagcagata
    15481 aatttaaata tcatgaagaa atgaaaaaga cattagaaga tgaaccaaat cttgatatag
    15541 ctatggatga agttgtagaa atacttcatg aaggaaatgt tgtaatagga gttggaacta
    15601 aactaggatg ttcatttaaa tctaaagctg taatattggc cactggagtt tatctgaact
    15661 caaagatata tatgggtgaa gttgcatttt atgaaggtcc taatgcattg gggtatgcaa
    15721 aatatcttac agatagctta gttgagcttg gccttagaat gagaagattt aagacgggaa
    15781 ctccagcaag agttcataga gatagtatag acttctctgt aatgtcttta caagagggtg
    15841 atgaaaaagt aactccattc tcatttatga atgaaaatat agaaaaaaaa caagaacctt
    15901 gttatttaac aagaactaca gaagaaactc aaaaagttat actggataat ttaaaaaggt
    15961 ctgctatgta tagtggagta atagaaagta ctggtccaag atactgtcct tctatagaag
    16021 ataaagtagt aagatttagt gataaaacat cacatcaatt atttatagaa ccagaagggt
    16081 taaatactaa agaaatgtat atacaaggaa tttcaactag tttacctttt gaagttcaat
    16141 tagatatgta caaaactata aagggacttg aaaattgtaa gataatgaga cctgcatatg
    16201 ctattgaata tgattgtgtt gacccaactc aactaaaaat aagtttggaa ataaagggtg
    16261 ttgagaactt atttagtgca gggcaattta atggaacttc tggatacgag gaagcagcag
    16321 ctcaagggct tatggctggt ataaatgcag ttagaaagat agaaggaaaa gagccatttg
    16381 tattagaccg ttcagaagct tatataggtg tcttattaga tgaccttgtt actaaaggaa
    16441 ctaacgagcc ttacagaatg atgacatcaa gagcagaata tcgactatat ttaagacaag
    16501 ataatgcaga tatgagatta actcaaaaag gttatgatat aggattagtt aaaaaagata
    16561 gatatgaaag gttcctaaat aaaaaggctg ctgtagagaa agaatttgaa agactaaaaa
    16621 atgaaagagt tacaccaaaa gaagtaaata gtttgttaga agaaaaagga gcaacaccaa
    16681 taaaggttgg aatatctcta tatgaatttt taaagagacc agaggttact tacgaattgc
    16741 ttgaagaatt agggaaaggc gctggagaag atgtttcaag agaagttaaa gaacagtgtg
    16801 taataataac taaatatgaa ggttatatag agaaacaatt gaaacaaata gaccaattta
    16861 aaaaacttga gaataaaaag ctggatgaga aaataaatta ttcatctata gaaggtctta
    16921 gattagaggc tagacagaaa ctagatgata taaaacctat ttcaataggg caagcatctc
    16981 gtatatctgg tgtttctcca gctgatatat cagttttact tatataccta gaacaaatca
    17041 gaagaactag aggtggcaaa ggtgaataat atagaacttc tgaaaaacgg gattgaaggt
    17101 tttaatatag atacgaatga cagtatgtta gaaaaattta aaatctatag agagatatta
    17161 gttgactgga ataaaaagat gaatcttact ggaatagaag atgaaaaaga agtgtatata
    17221 aaacattttt tagactctat ttcagctgta aagaatggat atataaaaaa tgggatgtct
    17281 ataatagatg ttggtacagg tgctggtttt cctggaatac cattgaaaat atgtttagat
    17341 agcttagaac ttactttgtt agattcgtta aataaaagaa taaacttttt agaggaagtt
    17401 agtagagtac tagagttaga taatattaca tttatacatg gaagagctga agattttggt
    17461 aaaaatgaag actataggga aaaatatgat gttgctacgg caagagctgt tgctggatta
    17521 ccgattctta tggaattttg tgtaccattt gtaaaagttg gagggtattt tatttgctta
    17581 aaaggtccga atgctaattt agagctagaa gaatcacaaa aggctattga tgttttagga
    17641 ttggagtata ttgaaaaaat agatgtagag ttaccagagg tagatttaaa tcataatata
    17701 ttagttttta aaaaagtgat ggaaacacca gttaagtacc ctagaaaagc tggtaaacca
    17761 gccaaaaatc ctattaagta atgaaaaatt tattattggt aagcttaatt atttctcagg
    17821 aaataattaa gcttactgta aaaaaacaaa aataaaggaa ttattaaagt agatgcagaa
    17881 ataaatttgt atgtacatat agagaacaaa aataatttat atctaaaata agagaggtat
    17941 gttatggaag ataaaagagt tatggagata cctatagaag atgtagttcc aaatccatat
    18001 caaccaagaa aaatattttc acaagtttca ttggaggaat tgagcaattc tataaaggta
    18061 tatggtataa ttcaacctat aacagttaga gcaaaagatg gcaaatatga actaattgca
    18121 ggagaaagaa gattaagagc agctaaatta gcagagctta aaaccatacc agcaattata
    18181 aataatatga acgatgaatc ttctgctgtt ctagcgttat tagaaaattt gcaacgagaa
    18241 gacttaaatt tcattgaaga agcaattggt tatgaaaact taataaaaga acatgctttt
    18301 actcaacagc aattagcaga aaaattgggc aaaaatcaat ctactgtagc aaataagctt
    18361 agaatattaa agcttccaaa cgatataaaa atgaagctaa tagagaataa tttaacagaa
    18421 agacatgcta gagcatttct taaactacca agtgaagatt taatgcaaag tgtgttagac
    18481 aaagtcataa aaaatgaatt gactgttaaa aaaacagaaa aattgataca agatgtatta
    18541 gaagaaacta aagttcaaga agagcctgat aaaaaacaga atataaaggg tgctatgagt
    18601 ataagaattt acataaatac tataaagcag gcctttgatg ctatatcaaa tacaggaatt
    18661 gatgctaagt ataatgaaat agataaggga gattatatgg aagttgttgt aaaaatccct
    18721 aaaaaataga gattactgct taccagtaat ctttttttgt aatataagcc ttgtaatata
    18781 aattgattta tagacattat ttatacttaa aaaacaccta ttcaacattt aaaattaatt
    18841 taattcttaa aggggggaac atcatgggca aagttatagc tgtattcaat caaaagggtg
    18901 gagtcgggaa aactacaaca aatgtaaatt taagtgctag cttaggaact ttgggaaaga
    18961 aaatattagt attagattta gacccacaag gaaatacaac tagtggatat ggtattaata
    19021 aaaacgaagt agaaaataca atctatgaaa ttatgttaga tgggttacat attaaagaag
    19081 caataataag tactgaattt gagaatgtag atgtagttcc atcagctact gaactatcag
    19141 gtgcagagat agagcttaca tctaaaacta atagagagta tattttaaaa aattccataa
    19201 aagcggtaat agatgaatat gattatatat ttttagattg tccaccctca ctggggatgc
    19261 ttacaataaa ttgtttaact gctgtagata gtgttttaat tccaatacaa tgtgaatatt
    19321 atgctttaga aggtgttagt caattaatgg agactataaa attagtaaaa tcaagattaa
    19381 atgctgatat agaaattcaa ggtgttgttt taagtatgtt tgatggaaga gctaatttat
    19441 caatacaagt agttgaagaa gttaagaaat actttaaagg tagtgtatat acaactttaa
    19501 ttccaagaaa tgtaagactt gcagaagctc caagtcatgg aaaacctgta atttattatg
    19561 ataaaagatg tagagggtct gtagcttatt tggagctagc agaagaattt atagatttag
    19621 aagaggagga atggtagtat ggagaataag tctaaaagaa gtaatagatt aggtagaggt
    19681 cttagtgcat tgataccaga aattaaagga gaaacttcag aaaaagaaat agtcaacata
    19741 gatatagaca aaatatatcc aaacgaagtt caacctagaa agcaatttga tgaagaaaag
    19801 ataaaagtat tgtcggattc tataaaaaat tatggtgttt tacagccaat agtggttaaa
    19861 atggatgaaa ataataaata tatgataata gctggagaaa gaagatttag agcatcaaaa
    19921 cttgcaaata aaaatcaaat acctgctata attaaagata tagatatgaa agatataatg
    19981 gagatagcct taattgaaaa cttacagagg gaagatttaa attcaataga agaggctcta
    20041 gcatataaga gtttaataga gcattacaat gtaactcagg aagaaatatc agaagctgtt
    20101 gggaagagta gacctcatat aactaataca ctaagacttt taaatcttgg acaagatgtt
    20161 atagaaatga tagacagtgg tagaatcaca gcaggccatg gtaaggcttt attgagaatt
    20221 gcagataaag atttgcaact tcaaatagcg aaaaaaatag aagaagaaga actttctgta
    20281 agagaagtcg aaaatatagc taaaaaaata tctgaaaata aacaagaaga acctaaaaaa
    20341 tctaaaccta aggatgtatt tattttagat gttgaagata aacttagaaa tatatttgga
    20401 acaaaggtga atatttctaa aggaaagaaa aaaggtaaaa tagagataga atactataat
    20461 gatgatgatt taaatagtat tgtatcaatg cttcttgaat agaacaaaaa tataaaacag
    20521 agaggaagat tgttatgatt tatttagata atgctgcaac tacatatcca aaaccagaaa
    20581 gagtgtataa tgctgtttta gattgtatga aaaattattg tgcaaatcca ggtagagcag
    20641 gccataaact tgctatgaga gctgctaggg agatatatga tacaagagag aatatagcta
    20701 agttgttcaa tgtaagtaat cctatgaata tagtatttac atctaatgca acagattctt
    20761 taaatttagc gataaaaggt gtattacaag aaggagacca tgtaataaca acgtctatgg
    20821 agcataattc agtaataaga cctataaaag cattggaaaa aaggggtatt gaaaatactg
    20881 tagtaaaatg cgattatgag ggatttttag attatgaaga tttagaaaaa tcaataaaga
    20941 gtaatactaa actgattgta acaacacatg cgtctaatgt atgtggaact ttaatagata
    21001 taaaaaaagt tggagaaata gctaaaaaac ataatatact atttttagta gatgcatcac
    21061 aaacagcagg tgtttatgat atagacgtaa atgaatgtaa tatagatatg ttggcaatgc
    21121 caggtcataa atgcttattt ggacctcaag gaacaggtat attatatgta agagaagggt
    21181 tgaacttaaa tatattaaaa gaaggtggaa caggtagtaa atcagaagaa atagttcaac
    21241 cagagttatt cccagataaa tatgaatcag gaactcataa tactccaggt atagcaggtc
    21301 ttaaccaagg tatactattt atatttgaaa gaggaatcaa caatataaga caacatgaag
    21361 aagaattatg tcaatatatg atagacaaat tagaggaagt accagatata aagatatatg
    21421 gaccaaagga cagtaaaaaa agagcatcag taatagctct aaatatagga gatatggatt
    21481 ctggagaggt tactttctta ttagatagtg attataatat agcgactaga tcaggaatac
    21541 attgttcacc actagcacat accactttag gtactttaaa acaaggtgca gtaaggttca
    21601 gtataggata tttcaacaca aaagatgaga tagataaagc agtggaagct ttgaaaaaaa
    21661 tttcaaaaaa taaatagcat gagatttaat aatatagaaa taaaaaaggg gatatttcaa
    21721 aataaaaatt tgaatcatct ccttttttgt acaaaaaaga aaaggggtcc ctaagaacct
    21781 ctaatctatt tgataattgt tttaagaagt tactttaagt aatctccttc ttcaagaact
    21841 atatgaccac tttcgtaatt agaaccatca acagtaattt ttatttgttc aacattcata
    21901 ttttttatgt aagtacgagc aactgaatca agcattaaag tttctgcatc actacctaag
    21961 tttgactttg taaagtcaga gctaacatct aatataccag tttttacacc atcaatgtct
    22021 tttgtagtaa atgaatttaa ttttgcagat tctggaacaa ctttaagttt ttgaagttct
    22081 tcaaataaag tgttctcatc aattttattt aaatcaactt tattttcaat taaatctgtc
    22141 ttatctacat caaaagagta aatagtagct gattgagctt tagtttcttc ttttggagta
    22201 agtttagctt tgttattagg aacctctttt tcagtattgt tttcttcttt tggttgctca
    22261 acatttgtat tgctcttagt ttctttttta gatgaatcac ttccattttg agcattagta
    22321 caaccaactg cgaatataga tatagataat atacttaaca ctaacattat tttcttattt
    22381 ttcataaaaa tttctcctct cttaaaaact attcttatat ataattatag tcgttatgag
    22441 caaatatatg aatacaaaat agtaacaaat ttaaaaaatg atttatttaa attaataaaa
    22501 ctcaaaataa actaaatttt agtcattttt atgggaaatc atttaatgta cagtgaaaat
    22561 attgtaaaat aaaagtagtg tttttaaaat aaatataagt tataattata ttataaaaaa
    22621 atgtcttcaa aaggtgggaa tagtatggaa attttgagct taggagaaaa gattaaaaag
    22681 ttaagaaaag aaaaaaacat gacattgaaa gaattagctg gagataggat aacagcagca
    22741 caaataagcc atatagagag agataaatct catactagtt atgaactgtt ggaatatcta
    22801 ggcgataagc tagatgtaag tgtagaatac ttattagaga ccaaggaaat gcaatcaaaa
    22861 aagataactg ataatttaat actacagagc gaaatttata taaaagaaaa tgaattaaac
    22921 aaggctgagg accaaataaa agaagtttta gatatatgta agagatacga tttaatggag
    22981 aactatggca gatgtaattt tttaatggct aatattaatt tgaaaaaatc taattataat
    23041 gatgctatag aaaactttga aaaggcattg tacttcttta taaaaaatag tgatagtgaa
    23101 aatatactta agtgttattt aaacataggg aaaatatata tgcaggaaga cttttataaa
    23161 ggtgctataa gccactttaa ttttgcagag gaaattttgt cagagaataa atttgaggat
    23221 gttaacatac acaaggaact atatagtaag atggcatatt gttacataaa actagataat
    23281 ccaaatatgt cattgaagta catagaaaag ataaatgaaa tagataatag aaatgataga
    23341 aaagaagatg tcgatatttt ggtgttaaaa gcaaataata tgcttgagat tggaaaatat
    23401 gaagaatcaa gagattactt taaaaaagca ctaaaaatac ttgagagtga ggataataaa
    23461 actggattag caaatgtgta tttaacaatt tgtgatgttt acagaaaaat aggtgaaaca
    23521 gatagagtac ttgaatattc acaaaaggta tatgacataa agaaaaatga tgaagatgaa
    23581 tacatgatgt caggattatt taagataata gaagcatata tagataaaga agattatgat
    23641 ttagctagaa aatattgtaa gatagcctta gcttcatcaa taaaaaataa aaataaattc
    23701 aatgaatata aagcattgag attctatgct aatatgtata aaaatcagaa tgaagtaact
    23761 cttgcaattg aatatctgat taaatgcata aaaatagtat cagatttagg caacaataga
    23821 atattggcca atttatatat agacttaggt caattatatt caaatatatc aaaagaaaaa
    23881 gagttagaat attatcaaaa aggtgtattt atgtacaaaa acttagaaat aatgtagggt
    23941 aaataaacct ataagggtat agaaacaatc tataacaagc aagataatat ctatgataaa
    24001 atataaattg tatgaatatt tttaaggaga tgaatcagac aatgagtata aaaatagatg
    24061 cgagagggct tgcttgtcct aaaccagtta taaatacaaa aagagaattg gataacctag
    24121 aagaaggtgt tgtagttaca atagttgata atgaaacagc taaggagaat atattaaaac
    24181 ttgctaaatc tttaagttgt gaagcaaata ttgttgacga aaaagagaat tttatatcta
    24241 tagaaattag aaaaggtaaa aatatactag ataaacaaaa tgttgtagat aataaagaaa
    24301 gtgaattaga caatacatgt atatttatat cttcagataa gatgggactt ggaaatgacg
    24361 aattaggaaa agtgttaata aaaggattta tatatacatt aacagaatct aaaccttatc
    24421 ctaagtatgt acttttagtt aatggaggag taaaattaag tgctgaaaat gaagaaacca
    24481 tagaaaatct aaaaatactt gagaatatgg gtgtagaagt tttatcttgt ggtacttgtt
    24541 tagattatta taatttaaaa gacaaattac aagtaggtac agttacaaat atgtatacta
    24601 tagttgagac attaaagaat gcatcaaata ccatttctat ataatgtatg tatgtttaat
    24661 aatataaaac taacaataaa gattaactca aatagatagt cagaaaggat taagtaatga
    24721 atcaaatgta tatagtgtca tttaattcga cacatcatgc gataagatca gaaaagttat
    24781 ttggtgaaaa tagtctaaaa gtaatggctc ttccaacacc aagagaaata acagcaagtt
    24841 gtggaatatc aattaaattt tcttttgaag atatggaaaa gataaaaact attttggttg
    24901 aaaataatgt agatataaaa ggaatttatt gtataagtaa attagaaaat ggttcaaaag
    24961 aagtagagaa gttagattag gaggctaatt atttatgcca atggatttaa aaataggtga
    25021 tattgttgaa ttaaaaaagc aacatgcatg tgggtgtaaa gagtttgaaa tcataagaac
    25081 gggaatggat ataaagataa aatgtactaa atgttcaagg ctaataatgc ttgatagaga
    25141 gaccttagaa aagagagtaa aaaagctaat aaaaaagtga taaaaattta acacttaaaa
    25201 aatgtcaaat accgtatatt aatatccaaa attttggtat aataagaatt gaagaaaaca
    25261 ttttcatggg ggtgctttaa ttatggcagt taaatatgca aaaagaatgc aaggattaca
    25321 aggatcagaa atacgtgagc ttttaaaact tactcaacaa ccacaaataa tatcttttgc
    25381 tggtggaatg ccggctccag agttatttcc agttgaggaa atgaaaaaag tatcagttgc
    25441 agtgcttgaa gaaaatggaa gatcagctat gcaatatact acaacagaag gatatgaacc
    25501 attaagagaa aaaatagcag ctagaatgaa tgataaaaac aaaactaatg taaacaaaga
    25561 tgatatatta gttacaagtg gttctcaaca aggtctagat tttgcaggaa aagtattcat
    25621 tgatgagggt gatgtaattt tatgtgaaag tccatcttac ataggagcta taaacgcatt
    25681 taaatcttat caacctaaat tcatagatgt tccaacagat tctgatggaa tgataatgga
    25741 agaattagaa aagatactag aaacaactga tagaataaaa atgatttacg taatacctga
    25801 cttccaaaat ccaacaggaa gaacttggcc acttgaaaga cgtaaaaaat tcatggaaat
    25861 agtaaataaa tttgaaatac cagtaataga agataatcca tatggagatt taagatttga
    25921 aggagagact ttaccatctt taaaatcaat ggatacaaaa ggattagtaa tattcttagg
    25981 aactttctct aaaatattct gcccaggata cagattagga tggacttgtg cttctccaga
    26041 aattttatct aagtttaact ttgcaaaaca aggtgcagac ttacaagcat caactatatc
    26101 tcaaatggaa gtaagcaaat ttatggatat gtatgaccta gatgcacatg ttgacaaaat
    26161 aaaagcagtt tatgttaaac gtagagatgt aatgcttaag actatggaag aagagttccc
    26221 agaaggatta gtatttactc atccagaagg tggattattt acatgggtag agcttccaag
    26281 taatttaaat gctaaagaat taatgccaaa atgtttagat aagaatgttg cttatgttgc
    26341 tggaggagga ttcttcccta atggtggtag agaaaatact ttcagactta actattcaaa
    26401 tatgccagaa gaaaaaataa tagaaggtat aaaaaatata gcagctgtat taaaagaagc
    26461 tatgggtgta gaagcttaat taaaaataat aacttatata taatacaagg gatggttgtt
    26521 gccatccctt gtttgtttga aaagtatata attcacctta tactaaactt tgtccaaaat
    26581 ttaaattgac agaaataaga ataaatgata aaatgtgtag gtatgagatt ttagtctcat
    26641 ttctctgctc taagagtgta gagccgttaa gtccaaaggg aggtgaatta tagtgagaaa
    26701 ttatgaatta gtttatgtgg taaagccaaa ctctgatgaa gaagtaagag aggctatact
    26761 aaacaaagtt aaggaagttg ttgcaactga cggagaaata gttaaagttg atacttgggg
    26821 aactaaaaaa ttagcttatc caatagctaa gtttacagaa ggtttctatg tattagttaa
    26881 cttcaaatca gcagtagacg ttcctaaaga gatagacaga aacttaaaga taaatgaaaa
    26941 cgtaataaga cacatgatag ttgttgctta ataactggtt ttattataaa aaataggtgg
    27001 tgtttttatg aatcaagttg tattagtggg aaggttgact agagaccctg aattaagata
    27061 catcccaggt acaggaacac cagtggcatc ctttacaata gccattgata gagactatgt
    27121 aaaaaaagat ggatctaaag aaactgattt tatacctgtt gaagtaatgg gtaaatctgc
    27181 tgaattttgt gctaactaca taactaaagg tagattagta gcacttcaag gatctataag
    27241 agtagacaat tatcagacac aatcaggtga aaagagaact tttacaaaag taagtactag
    27301 atcagtacaa gctttggata gtaagaataa atcggaaaat tcatatagag agagtgctcc
    27361 agcttttgag ccaagctttg aacctcaagg tttagaccca caaggtttcc aagctataga
    27421 tgatgacgat ataccatttt aaaaaggagg gaaaaaagtc atgatgaata aaaaaagacg
    27481 taagaaaaaa agagtttgtc aattttgtgc tgacaaaaac gctaaaatag attacaaaag
    27541 tactcaaaga ttacaaaagt atataactga aagaggaaag atattaccaa gaagaatatc
    27601 tggaacttgt gctaagcatc aaagagaatt aacagttgct ataaaaagag cgagaaatat
    27661 agcactttta ccatatacat tagactaaaa aaatgagcct tgtgctcatt ttttattata
    27721 tgtatttata tatctaaatg aggcgagcta taaagctcgt ttttttgttt atatacttaa
    27781 atatattatt atttatgata taatattata tattaaggag ggttgtaaac gtgaaaatag
    27841 ataaaggttc tgagataacg agaaacataa agataataga atggatgaaa acagaaatat
    27901 taatgagtgt aagtgatttg tttaatttat tgtttaaagg ggtaaaacca ttagatgaag
    27961 caattcaaga tactttagca aatataataa tgataacata tctcttagca aagagattag
    28021 gaattagttt tagagatgtg gattataaag tcaaggaaaa aataaaaatt ggtatagatg
    28081 aggaccatag cgttgaaaga tggtatggag atttatctaa tttaaaaaaa catatggata
    28141 atagggagtg atattaaatt gaataataaa attagactat ctaaggcaat gtctataata
    28201 gttttagcta taataatcgc tttagtaata gcctatattc caatgctagg aatatttagt
    28261 atgttagcag ctgttccata tgtaattata ggtgctatta ctgatagaaa gtattctctt
    28321 atatctattt tggttacatt ttgtgtactg attctatttg cagacatttc ttatgcatta
    28381 aatatatgta taatgtattc tttaccaggt atagtaatag gaaagatgct aaagagaagc
    28441 tttgaacaag aggacagtaa taaattcgaa ccgatatatg gtggaaccat aatatttgta
    28501 ctttcaatgc ttgtatattt ttttgtatta aagacatttt taaatgtgaa tctattagat
    28561 gaagtttcta agatgatatc agaaattgta aatattcaaa aaaatagttt ttctgcaact
    28621 gaacttaaag tgtttgataa aatgaagcca gatgagattg taagttattt tacaaatatg
    28681 ctaccaatga tgttattttt acaagggttg ttatcagcgt ttgtcacata ttatttgagt
    28741 gtatttttta taaaaaggat tacaaagatg aatataagat ttcctaagtt tgctgatttt
    28801 tatttaccgg gaaatgctat actcacaact ttcttacttt atttattagt cttatttatt
    28861 caaattattg gttcaaaatt atatacagaa ttaataatga ctaatttaca gctagttttt
    28921 aatttaatgt ttgtaattca aggtatagca gtttgcattt atttcttaaa gaaatggata
    28981 agacagggac caaataaaat tatgtttttt tcagggataa ttttatgttt atttggattt
    29041 atgggaatat cttttgttgg tatggtagat agtataattg actttagaaa ggtaagaagc
    29101 tataaatcca cttaggagga tagaaatgag taataaacaa acctttaaat taaatatgcc
    29161 agaaataaat ttatatataa ttgttattgg tatttctagt ataattttgc tttattacaa
    29221 cttgtatgta gggtgtttat ttttctgtat ttttgtatat atggtttttc acaattggag
    29281 aactactaat attagacgtc atgaatggac agagtatatt caaaatttat ctttagatat
    29341 agatgaaaca actaaaaaag ccataataaa tcttccaata ccattatgta ttttagaatt
    29401 tgatggaaat atatcctggt ataatggaaa gttttatgat atgattggtc aaaaagattt
    29461 acttgataaa aatatagagg atatagttaa aaatcttaat ttaagaaaag tattaaatga
    29521 aaataaagag atgtacacag aaataaacta taaagaaaaa gaatatacaa taatttataa
    29581 tgttataaaa aatgatcaag aaaaaaatcc taaatatttg atgatattat actggataga
    29641 caagactgaa tatttaaaag taaaacaaaa ttatgatgat gaaaaaaatg caatgatgct
    29701 aatacaagta gatggatatg atgaagtatt aaaaagtgca gcagaagata agagagcttt
    29761 aattaatgtt gaagtagaga aaatactttc tgctttagaa ttaaattcaa atggtgcatt
    29821 gagaagaact tcaaaagaca aattcttctt ggtaatgcat aaaaaagagt taaaaaaatt
    29881 ggaagctgag aagttttcta ttttagatac aataagacat attgattatg gaaataatct
    29941 tcctgttact ataagtatag gaattggtat agatggagat acattaaatg agaacctaaa
    30001 acttgctacg ggtgctctcg atttagcact tggtagaggt ggtgaccagg ctgttgtaaa
    30061 aacaaaagat aaatttgtgt tttatggagg aaaatctaaa gctgtagaaa agaaaaccaa
    30121 agtaaaatcc agattaatag gtcatgcttt aagagaggtt atacaacaaa gtgaccaagt
    30181 ttatataatg ggacataaat atcctgatat ggatgctatg ggagcagcag ttggtgttta
    30241 tgatatatgt aaatcctgta acaaaactgc aaacatagtt ttacaatctg taaatgaatc
    30301 tatagaaata tttataaata aaataaatga aaataattac tataaaaagt tgtttattgg
    30361 aaaagaggaa gctattgaca actgcactaa aaatacatta gttgtagtag ttgatactca
    30421 tagaccaaat tatactgaat gtgaagaact gttaaagcta tcagagaagg tagtagttat
    30481 agaccatcat agaagaggtg tagagtttat aaatgatgca gtgcttttat tccatgagat
    30541 atatgtatcc tcaacgtgtg aaatggttac agagttagtt cagtatatgg atgaagatgt
    30601 aacaataaat aaacttacag ctgaagggct tttagcaggt ataagtctag atactaaaaa
    30661 ctttgcattc aaaacaggtg ttagaacttt tgaagctgct tcttacctta gaaaagttgg
    30721 agcagatact atagaggtaa agaaattctt caattctgat gtaaaagatt tcataataaa
    30781 agctgaaata attcaaagta ctaaaataat taataataga atatgtttag catattcaag
    30841 tactgagata gatagtataa atgttataat agctcaaact gctgatgagt tattgaatat
    30901 caaagaagta gaagcttcct ttgtattagg tgaaaaagat gatactatat ttataagtgc
    30961 gaggtcttta ggacaaataa atgtacatgt acttatggaa aaattaggag gcgggggaca
    31021 catagatata gctggagcac agttaaaaaa tgtttctcta aaagaagctt ataagatggt
    31081 aaataaaata atagaggagt atttggagga ggaagaatag atgaaagtta tattattaaa
    31141 agacgtaaaa ggaactggta aaaagggaga aatgaaagaa gtaagtgatg gatatgcaag
    31201 aaatttctta tttcctaaaa agatggctgt gcaagcagat agtgtagcaa taaaagaatt
    31261 aaatgaaaag aataaatcta aagaaataaa agcacaaaaa gagtatgaag aagcagtttt
    31321 attaggtaag caaatggaag aaattaatat agaaatatat tcaaaagcag gagaaggtgg
    31381 aagattattt ggttcaataa cttctaaaga aattgctgag caattaaaga aacaaaaaga
    31441 catagatgta gataaaagaa aaatattatt agatgaaccg ataagatctt taggttcaac
    31501 tttcgtagaa ataaaaatac atcaaaaagt aactactaaa ataagagtgg atgtaaaaga
    31561 aaaacagtaa taactagagg tgattaagat ggaagatatg acgagaattc ctcctcatag
    31621 tgtagaatca gaacaatcaa tattgggttc tatacttcta gataaagatg ctataataac
    31681 ggttacagaa actataaagc ctgatgattt ctataaagag gctcacaaaa taatatatga
    31741 atgtatgata actttaagta ataaaggtga gcctatagac ttgataacat taacagaaga
    31801 actaagaaaa caagggcatc ttaatgatat tggaggaatc agttatatta caagtctttc
    31861 tactatagta ccgacgactt caaatgtaaa atactatgct gatatagtaa aagaaaagtc
    31921 tgtacttaga aagcttataa aagcttctaa tgaaataata aatctaggat atagtggagc
    31981 aactaagatt gaagatgttt tagaacaagc tgaaaagagt atatttgata tatcacagga
    32041 gaaaactagt gatgatttta aatctataaa cttagttttg atggatgcct atgatatgat
    32101 agaaaaatta tacactaaca agagtgatgt cactggtata actactggtt ttaaagattt
    32161 aaacaaaaaa ataaatggtc ttcaaaggac tgatttaata ttaattgcag ctagaccagc
    32221 aatgggtaaa actgcctttt ctttaaactt ggttcaaaat gcagccttaa aaggtgatgc
    32281 ctctgtagct gtatttagtt tagagatgtc taaggaacaa ttagtacaac gtatgttatc
    32341 ttcacaatct agtgtagaat taaaaaaaat aaagactgga acacttaatg ataatgattg
    32401 gcctagaatt atagatgcta tggcagtatt atcagatgcc aaaatacaca tagatgatac
    32461 tcctggtata aaaatatcag aactaaggtc aaagtgtaga aagttaaaaa tagaaaaagg
    32521 actagattta gtgcttattg attatcttca acttatggaa ggtgaaggta ataatgaaag
    32581 cagacaacaa gagatatcta agatatcaag gtcactaaaa atattagcaa aagaattaaa
    32641 ctgtcctgta gtagcactat ctcagttatc acgtgcacca gaacaaagag cagaccatag
    32701 acctatgtta tctgatttaa gagagtctgg agcaatagaa caggatgcag atatagttat
    32761 gttcttatac agggacgaat attatcatgc tgattctgag agtaaaaata taggagaagt
    32821 aataatagca aaaaatagac acggtgaaac tggttctgtg gaacttgttt ggcttggtga
    32881 agttcaaaga tttggggata agttgagaga cctataatct aacgaatatc cacagaacgt
    32941 cctttctttc tacaggaaaa atgtggatac atgtcactaa atatgtccaa acattgaaat
    33001 ttagctaaaa aactatccac actatccaca gatggcctgt tgataagtgt gaataagtag
    33061 ataaagcaag cttttggctt gctttatctg tgtataaata ttaattatta ggaggaataa
    33121 tatggaaaaa ataagcttaa aatatatata tcccaatata attaaagtac ttgatgaaat
    33181 aaacttattt agagtaattg acaataattt aagagagtct attgttgttt atgctaataa
    33241 tgtggataat cagtatcata taaacatgac taatacaaac tttggaaaca taattaacat
    33301 atgtaaatta gaaaaacttt tagatgtgga taaatttatg gaaaaagtta taaaatatga
    33361 aaaagaaata atagagaaag aagagttttc aaaaatagaa gaatatatgt taaatattgg
    33421 agaatactaa aaaagttgaa aaaaatacga atgtttgata gaataagtaa gtaaagtgtt
    33481 cgagagtata taaaatatag aggtgaatta catgaaaaca gttgcaattg ttggttctca
    33541 atggggagat gaaggtaaag gtaaagttat agattatctt gctactcaag cagatgtagt
    33601 agtaagaggg caaggtggaa ataatgcagg acatacatta gttgtagaag gtaaaaaata
    33661 cgcattacat ctaattccat ctggagtttt aaatccaaat acagtgaata taatcggaaa
    33721 tggaatagtg tttgacccta aaggattttt agaagaattg gaaatgttta aaacggataa
    33781 tataagtaca gaaaatataa aaataagtga tagagcacat gtcatattcc catatcataa
    33841 agaactagat gcattgtcag aagaagccag aggcgattta aagataggta caacaaaaaa
    33901 aggtattgga ccttgttata tggataaaac agagagatct ggtattagaa tatgtgactt
    33961 aatggataaa gataaatttg ctataaaatt aaaagctcaa atagatgcta aaaatgaaat
    34021 agttaaaaat atatatggaa aagaagaatt atttgatttt gaaactatat ataacgaata
    34081 tctaggatat gcagaacaaa taagaaaata tgtggcagat acgtctgtta ttgtatatga
    34141 tgcagtaaga gcaggtaaaa aagtattgtt tgaaggagca caagggactt tattagattt
    34201 agatttagga acttatccat ttgttacatc ttctcatcca acatctggtg gatttgcaat
    34261 tggtgcaggt ataggaccaa atatgataaa agacgttgtt ggtatagtaa aagcatatac
    34321 tacaagagtt ggagaaggac cgtttgttac agagcaaata aatgaaactg gagataagat
    34381 aagagaacaa ggacatgaat ttggggtaac tactggtaga ccaagaagat gtgggtggtt
    34441 tgatgcagtt atagttaagt atgcagctag agttaatgga ttgactagta tttcatttat
    34501 gttacttgat gtattaactg gatttgataa gataaaagtt tgtacgtctt ataaaatggg
    34561 cgataagata ataacggatt tcccagcttc attagatgat ttagcaaaat gtgaacctgt
    34621 atatgaagaa ttagatggat ggaatgaaga tataactcaa atagataact ttgatgacct
    34681 tccagaaaat gcaaagaaat atgtagcaaa aatagaagaa ctagttggag taagtgtaga
    34741 tatggtttct gttggtccaa atagagctca aactataata agaagaaata tatttgctta
    34801 atattttatc aattaaataa tttaaaatag ttgaagaaga gtatctcaag ataatgttta
    34861 tagttattag agatgctctt ttatatttta cttacattga ttttttatta agttaaagct
    34921 acttatacat attctagctg aaattaaagt tgaatttatg tagatacata taggtttttt
    34981 aaaaagaatt ttgttgaaaa taaatggcta aagatgattt taattatatt ctaaaaaaag
    35041 taaaaaaaac tattgactaa aaattatata gacgctataa tataacttgt gagtgaaaga
    35101 aacgacgaaa aaagtcgaaa aaatgtggtc tattagctca gtcggtagag cacctgactt
    35161 ttaatcaggg tgtcccgcgt tcgagtcgcg gatagatcac caaaatatgg ctcgttggtc
    35221 aagaggttaa gacaccgccc tttcacggcg gtaacagggg ttcaattccc ctacgagtca
    35281 ccagtatggg actatagctc agctgggaga gcacctgcct tacaagcagg gggtcacagg
    35341 ttcgagccct gttagtccca ccaaattttg aattagagat aaatactaga ttatatgctg
    35401 gtgtggctca acggtagagc agctgacttg taatcagcag gttgtaggtt cgattcctat
    35461 caccagctcc acaaagtaca taaattcaaa ttaatataat tttctatgtt acaggatact
    35521 tttaagtatc tttttttaat ttcattttta ttgtattaaa aatgaaatta aacatacaac
    35581 aaaattttga attacttgca atgtgatagt tttaaatata aaatttagaa tcattctagc
    35641 atagtattat gtaatatagc aaatttaatt tatagtatca ataaatatag actactaaga
    35701 atgtaaatga tttgttagat taagatacat tagatatgta aatagaaaaa taaaaagtat
    35761 gttttaattt atgtgatata agttttaaac agagaagcaa gtttgctctt acctctctat
    35821 ttaaaaataa aaaaatgttt tttaagggct attttattta aatctttccc atctcaaatc
    35881 atctccagta aattctaaaa tcctaaactt atctaatatt ctagagagag ttctttgagt
    35941 gtaagtattt cctatttgag atggtgttaa gttggttgaa ataatgattt ttttaccagc
    36001 aacaagtctt gtatttacaa tattgaagat ttctccacta gtaaaagaat tattaagttc
    36061 agttccaagg tcatctatta ttaataaatc acaatcaaac aagtttttat aattatcttc
    36121 acttatttga ttatttgtgt ctcttctaaa tttataatct tcaagaatat ctaaaattct
    36181 aaaagaagtt tgatagatta caacattgcc tttatctaac aattcctttg caatacaatt
    36241 gcacatatag gtctttccta gtccagtaga accataaaac agtagatttt cactattatc
    36301 cttcttaaaa tcatgaacaa aattttcgca gatacttaaa ttatttagca tattttctct
    36361 aggagatatt tcaccatcag agcctttctt aggagaaaat atattcaagt taaaattcga
    36421 aaaattttcc tgacttaaaa tcctatctaa attagacatt ttataagctt catttacaat
    36481 ttcttgtttg aggcaagaac atttttctcc attaggtaaa aatcctttat ctttacaaga
    36541 aatacattga aactttattt ccaagtaatc aagaggtatg ttactttcag ctaaaagtct
    36601 ttctttcttt acttttaaag actctatatt ctctttagtc ttctttacaa tttcatcttt
    36661 agacttagga tttaaaagta ctatcttagc taaactgaga cctattttag aaatttcatc
    36721 atctatagat tttatctcag ggattctatt atatacctca ttttttctat gttctaataa
    36781 gagttcatta tcatctcttc tcttagcata tttagcaagt atttttctta ttttatcctc
    36841 attcatttaa tcacctactt aaacttttct ttttgacttt ttttaataat ctcatcgagc
    36901 tcatcagagg tatactgagt gaatgtttcg ttgaaattat gaaacttagt ttttttgtaa
    36961 gtattgttgt tttgagtagt attaatctgc ttcttattaa tattctcctt aactatacgt
    37021 tcttcctctt tttgctttaa atcatttaaa ttttttatat ttttttcatt ccaattttta
    37081 attataccat ttatataaga tatacttggg tttgaaatat tcttagactt agaacatgca
    37141 tttattatca aatctatatc catattaaat ttatcaaacc aagtgtccat aagttctttt
    37201 tctgattttg atggttgtct tgaaaatccc aattcattga aaatcgtttt atataaaata
    37261 tatcgttcac ttcttaccaa aaagctttct tcaacatctt ttggcgtata taaatttgaa
    37321 tcataccaat ttctaataat gccttcaatg tatttaactg gctttgatgt accagtttta
    37381 tctttgacgt attcatatgc gcaaagtatc atatcggggc tcatattgta tttattcatt
    37441 atatccataa tactcatctt ttcgcttggg tcgagatatc gcccaactat tttatttata
    37501 gaattaaaca tttttctaat acttggattt tcagaagtag atacaacctt atctgtatta
    37561 gattttatag atgaattatt gcttaatata ttctcaatat agaaattttt taaatctaaa
    37621 aattctattg aataattaaa attatcatat tctccattgt catgtatttt tataatcttc
    37681 ttttcttccc agaatttcca agcagataac acatcagaca atggtatatt taggtttttg
    37741 gctattgaat tattgtcgaa cttaggatta gaagtaatat cacatgcttg tctatatcct
    37801 aaaagataaa cttttacgta taacccgtcc gccattggca taaatatatc tataaagata
    37861 ttgggaatag tgatttcacc taaatctatt tcattgcttt ctttaaaaaa cattttatca
    37921 cctcagatta aattatatca ttttttatat tatatttgtc tgtaaacaaa taaaaggtca
    37981 caagattagc atgtaaatat tttctaaaag tattcatttt gaaaaggagg agatattttg
    38041 gttataaaat tcaaccaaaa agtaagaaga acattatcag tagcgattct atttatggta
    38101 ttaataatag gttgctttat agaaaaggat gacagtttag agacatacaa agaaaaaact
    38161 aattcaaaaa taaatcagta taatatggat gttatatttg atgatgagac taagaggtta
    38221 atgtgcaatc agaatgttga ctacataaat aatacaaaat caaacttaga taaaatatat
    38281 ttccatatat atccgaatgc tttttccaag aaagattttg ctccttttga aaaaagtgaa
    38341 atgacaaggg cttatcctaa tggatttaac gaaggatata tagatataaa gaatatatta
    38401 aataataata gtaaaatgga gtataaaatt aaaggagaca aaaatgacat attagaaata
    38461 gaattaggga aagagttaaa accaaatgaa agaatgtcat tagatataaa atataacgta
    38521 aaaataccaa attcaattgg aagatttgga tatggagaaa atactataaa tgttactaat
    38581 tggtttccta tagcttgtgt aaatgatgaa aggggatgga atttaaagag ttatgaaact
    38641 attggcgacc cattttatag tgagactagc gattttcatg tgaaactatt gattccaaat
    38701 aaatataaaa ttgctcatac aggaaaactt attgatgata aacatgataa taagaaaatg
    38761 ctatatgaaa tagaagcgga aaacgttaga gattttgcat ttatactaag tagcaaattt
    38821 aatgtaaaca aagtagattc aaagggagta gctatcaata catataattt aaataaaaag
    38881 ctttctaaaa aagcaactga agtggcaaaa gattcaataa atatatttag tgaattattt
    38941 ggaaagtatc cttacaaaga attttctgtt gtagcaagtg acttttttat aggggggatg
    39001 gaatacccta tgcttgttat gatagaccaa agtttatata atgaaaaaaa tgaattttta
    39061 ctagaatatg ttattgccca tgagacagca catcaatggt ggtattctgc tgttggaaat
    39121 gatgaaataa gtgaaccctg gttagatgaa gcacttactg aatattctac aatagtttat
    39181 tttgaacaaa agtatggtaa agatatggca aacaagctta taaaaactat ggagatacag
    39241 acaaaaagtt atttgagcga aaatatattt aagccagcaa atgagtataa aaattctact
    39301 gaatacagct tgaatgttta tacaaaaggc gcaatagcat ttaatgaaat aagaaaagaa
    39361 gttggagata aagtattctt tgagacttta aatgagtact ataataaata taagcataaa
    39421 aatgctaatg gaagagcctt tgtggaacta tggaatagta aaggtgtaga tataaataag
    39481 attataagtg aatgtaagta aacagtgaat gtaagtaaat tttgtgtaga gtattaaatt
    39541 ttatttaata ctctgttttt ttggtataat ataatttata aggcagaaaa agaggtgaag
    39601 gaatgctaaa gtattgttca gtagggagtg gtagtagtgg taattgccac tatatagggt
    39661 ataaaaatac taatatacta gtagatgcag gattaagtgg caagagaata actacaggtc
    39721 ttaaagacat tggtgtagat gcagataaat taaaaggaat atttataaca catgagcatg
    39781 ttgaccatat aaaaggagca ggtatattat caagaaagtt tgatatacca gtatttgcta
    39841 atataaaaac atggtgttct atgaaggaca aattaggtga catcaaagat aagaatatga
    39901 aagtatttga aaatgataaa acctactcat taggtgatat catagtaaga cctttttcaa
    39961 tagaacatga tgcgtctgac ccagttggat ataattttta tacagagagt gatgaaaaaa
    40021 tgtctatagc tactgatata ggatgtataa ctcaaaatat aaaaaaacat ctatataaat
    40081 ctaaattagt agtattggaa tcaaattatg accctaatat gcttatgatg ggttcatata
    40141 catatgcttt aaagaaaaga gtaatgtcaa gtactggtca tttatccaat gaagatgcag
    40201 ctaatttctg cgttgaactt attaatgaag gtacagaatc tatattatta gcacatttga
    40261 gtaaagaaaa taattttcct gagttagcgt atgagacttc aaaaggagta ttagcatcaa
    40321 atgatatagt agttggacaa gatgtaaaac tagatgtact atcacgaaat gatgtttcta
    40381 atgtttatga gatgaagtag aggtgaataa ctttgctaaa gagaaatttt gaaaatgttg
    40441 aggataataa aattttatac tctataaagc agggtatgat tttagcgata cctgctatta
    40501 tgactggttc aacggctctt gtaattttga atcttccaat aaaggcttat caagaatatt
    40561 tatcaggctt gtttaatgga gaggttacaa atattcttaa ctttataaat gattctactt
    40621 taggaattat ttcattaata atattattaa caataagcta tagttatgga aaaatatatg
    40681 ggagcaagta tacagtactt gttcctatag ttgcaatgtg ctctttttta gtattttcac
    40741 atggtaatga gcttaattct tatatagaaa tatttaaaac aaagtggtta tttacatcta
    40801 taattgtttc tatgacatct tctgtattgt ttgtaaaact tacagaatct tttgttacaa
    40861 gtgtaaagtt tcatacagaa ggggctgatg cagactttaa tatggtagtt tcggctatag
    40921 ttcctttcat aatagtagta tttttgtttt ctatttttag agtgataatg ataagtctaa
    40981 ttggcagttc aaactttcaa gatatatttt ataatttatt ttcaaatgtt tttaataaaa
    41041 tgggaacaaa ccttatgagt gctctgttgt ttattttttt aatgcacttt atgtggtttt
    41101 ttgggattca tggtagtaat gtattagata ccgtcgcaaa aaatttattt gaaaatagta
    41161 tggcaattaa cataaattta gttaataata atcaattacc aacagaaatt tttactaaga
    41221 ccttttttga tacaatggtt ttattgggag gatgtggctc tttactatgt ttagtaattg
    41281 caatttttct tagtgaaaaa cgtataaatg taagaaagtt agctaaaatt gcttcaatac
    41341 cagctctttt taatatcaat gagatgctag ttttcgggat accaattgtt tttaactata
    41401 ttatgtttgt accttttgta attactccta taatcttaac catcacaagt tatgtggcta
    41461 tgtctacagg tattgtacca tgtacagttt cagctgtaga atggacctca cctatatttt
    41521 taagtggata tatgtctaca ggttcaataa gaggtagttt gttgcaagta tttaatttat
    41581 gtgttggtgt tatgatttat attccgttta taaaaatgtc gcaaaataga tatacatata
    41641 tgtttaaaaa taatatagaa aatttaacaa acttattaaa aaggtatgaa ttaacaggtg
    41701 aacagcctaa tcttctaaac cataatggta aaataggttc aatttcaaaa atgttggcat
    41761 cagacttgaa gtttgctatg aaaagaggag aaatagagct tttttatcaa ccacaagtca
    41821 attataatgg aaatgttgtg ggagcagagg gattacttag atggaaacat tcaataggag
    41881 ggttcattta tccaccacta gttataattt tggctaaaga agaagggttc ttagatgagc
    41941 ttggagagta tattattaat aaagcatgta ttgatttaaa gaagagtgaa aagctattga
    42001 gaaatcctgt taagttctct gtaaatatat ctccagacca acttgatgac cctaagttac
    42061 cagagcaaat aaaaaatatc attagtagta atgatataaa tcctaatatg ttaggtatag
    42121 aaataacaga gcaaattgca ttatcaggtt cacaaataat tattgaacgt atcaatgcga
    42181 tacataactt gggaataaag ttaattatgg atgattttgg gatggggcat agctctctta
    42241 tatatcttca aaataataac tttgatatag ttaaattgga tggttcatta gttaaagaga
    42301 tacttacaaa taaaagaagt agtgaaatta taatgactat tgtaaatctt tcaaaaaatt
    42361 tagattttga tatagttgtt gagtatgttg aaaatataga ccaaagggat aagttatatg
    42421 gtttaggatg tgaaatatat caaggatatt attatagcaa agcaatacct tttgaagagt
    42481 ttgtagaata tgcaaatcaa gaaagagaga tataatttta taagagcttg taaattctag
    42541 taatgcatag atttgtaata aaattaagtt taggagaaat atatgaatat aagtatagta
    42601 gtagtaggta aaattaaaga aaaatattta aaattaggta ttgatgagtt caagaaaagg
    42661 ctttctaagt attgtaagtt agaaattata gagttggatg atgaaaaagc tccagagaat
    42721 ttgagtgtta aggaaatgga aattataaaa gacaaagaag gaaagaaaat tttagggaag
    42781 ataaagcata atagttatgt tatagccttg gctattgatg gtaagggttt atcctctgaa
    42841 gaacttgcta agactatgag tgatttagca gttagaggta atagtagtct ctgttttata
    42901 ataggaggtt ctctagggct ttctgatgag gttttaggaa gggctgatta taggttatct
    42961 ttttctagga tgacttttcc tcatcagatg atgagattga tattgttaga acagatttat
    43021 agggcttata ggataaataa tggagaaccg tatcataaat aaatgatacg gttttttatg
    43081 atataattga attataaaat aaaatcaaaa tgtaaagtag gtgtagtaat ggacagacta
    43141 gatatattta tcgaaaatta tgattttaaa gaatatcttg aaaaattacc tagagaatta
    43201 atagaagaaa attataaaga ttttgttata gaattttgga aaaatcctag tgtagatatt
    43261 attaaactaa aatcaaaata tagtataaaa aatgtagtat ctataagtag tatattaatg
    43321 caaaatccta tccaagagta ttatgagttt cttgaagata tttggaaaaa taacataaaa
    43381 atagatgaat taattaataa gtatttaatt acagcaacaa gaatggatca aattaaattc
    43441 ccattaatat atattgatga agattctttt tgtccttatt gtttaggtaa taaattcaat
    43501 attattaata atattaagca acaagatata aaagttgaat gtgaaaagtg tggtgaggca
    43561 attagttatt ttattcataa ggaagaagta gataatataa tagaagaaga aaaaagaaaa
    43621 aaagaactat ttataagaac attggagaat gtatataata aaataaacaa gattaaatgt
    43681 catagatgcc aatcagattt atatgtgtgt attaatgata aaataatgga gtataatatt
    43741 aggtgtgata gatgtaattc acagtatgaa tcggttgaaa ttgcacagga acaatataga
    43801 ttatggcaac aaagagctgc aatgatggct aacataaaaa ataaagaaaa tgaattgttg
    43861 ctaaagacac tatcaattaa ggacgaaaaa gatattaaat ttaaactcga agatataatt
    43921 acggagagtg aaagtataga tgtaattagt gatttagtag atatgcaaga tagaggagag
    43981 aatattttca agcaattatt taataattat gttagactag gaagattaga cagaaggtta
    44041 ttggtaactg tgtgtaaaga ttgcaagcaa aatgaaaata cttatacatg ggaaagaggc
    44101 aaagaacatt taataaatat gagggggatt acatacagtg aagcagttgt atatgagtta
    44161 atggaaaaaa caaagctatt gccaataaga gcaattatta gaagacttat ggagaaaaaa
    44221 ctattgtatt gtgatgaaag gagcaataat ttacaagtac accctgtttt gattgaaaat
    44281 ttagctaaac tagaatcaat aaataaatct caaaatataa ataatcaagt agcttatcta
    44341 atattcaata agcaaaaata tatatgttat cattgtggtg aatcaggaag acccttaaag
    44401 ataggatatc taacaataga taaaaatata aatgatttat caagtttagt gggaatatgt
    44461 gatagttgct atgaagatat tactgaagat gaaattatta tagataatat tttttgtgtg
    44521 gtagatgaaa gaaacaatga attaggggaa gcttggaaat ttttaataca atatgatagt
    44581 agttttagaa ataatacaat tgcagaagta gagcatgcaa gattatatga tatgtatgat
    44641 gaagataatt taattcgtgc gtatgcaaat acattgtata aacaaacgaa agatgggttt
    44701 gctaatgaaa aagtattttt tgcatatgca agagcaatat tgaaaaatag caaagggcaa
    44761 gtaagtgtac tacaaatagc aaaagaaaaa tttaaattag aaaagtggtt aaatggataa
    44821 agggataata catattaaaa ttataaattt atataaaact gtattgcaat taagcaatac
    44881 ggtttttata tataagataa tgatacaatt aaccaaaatg tggtagtaca taagtgttat
    44941 gagatttaaa tattagcgat taaaataatg attaagtaaa attgtaattg atgaggagta
    45001 ttaacgtatt agtttatttt tatatataat taaaatatag gagggaagaa tgtgagtcat
    45061 agtaaactat ctgatcacaa attaaaaaag gggaaattta tagcaccttt taatgaattt
    45121 atgacaccat tgaatagtaa tgagtcatgg tgccttggtc gattgccaga gtatatatgg
    45181 ataggattat taataaataa atatggtaga aaaaaaggga tggaaataat ttataaaata
    45241 attgtaaaac ttcattcaat tgaatcagat attgtaacac ctaggttgtc tgagatttta
    45301 tctatggagg atgtaaagca ggatgaattc tttagttata ttctaactat tgttgaaaag
    45361 gaagctttat ctccattgac attaatattt acatatagta attatcctat ttttgttaaa
    45421 tattttgcag agccaagtat aaaaattgaa gatagggtta cctatttaga tgagacttta
    45481 agaaaagcta tgcatcatca aagtgaattt gctacagaca taagatttat agttttatat
    45541 tatttttgta tgtcaggaaa actcgtattg caaaaagaac agattaataa tttgctggaa
    45601 tatcctaatt tagaacacac tgatgaaaaa atgagaatgt tacgtccgtt tattcgtgca
    45661 gcagaattaa tggttttaaa tatggaaaaa aaatctgatt ggtatttaga tattttttgg
    45721 gggaggatta gtgttatgac tgaatgtaaa ttatacgcaa ctaaatttga agatgaaact
    45781 gctaatacag acttgtatat ggaacaatta catgagattt ttgtttattt atcagattta
    45841 ctatgtaaag taaatccatt agacgagaaa atgttagtat tacttggaat agcaatatat
    45901 tcttataaac gattacgaga agtagttgag cataaattat ttaattccat ttcaggtaga
    45961 ggctcagtaa gggtattgat agaaaattat attatgatga agtatttagt aaaaatagaa
    46021 gctcaacatg aaaatatatg gtcagaatat caattttatg gaataggtca atataaatta
    46081 attgtggcta gatatagaga acaagaacaa gatttaaaaa atagtcatgt tgattataaa
    46141 tatattgaag ctttagttaa tgaatttgta attgaagaaa caatagatat ggatactaaa
    46201 tattttgata agcaaaatat acgtagtaag gctgaaatag ttggagaaaa agagttatat
    46261 gggttgtact atgattatga ttccgcatat gaacatggtt tatggggatc aataagagaa
    46321 agttcaatgt taaagtgtga taatccagct catcactatc attgtatacc agatgtagac
    46381 aataatcaaa atttaaaaag tgtttggcat gattgtgtaa acataatgga aaaaacttta
    46441 cttttcttag atactgtata tggtatacca caacatttgc tattagaggt gataaaaaat
    46501 ggaaaagaat tttttactaa ataaaataaa tagtattcag aaggaatatt tagaattatt
    46561 agtaaagtta aaagataata tagatactat agattatatt tatataatag atgaaataaa
    46621 tatattttgg tattcatata gagatgttat aaagctttac ttagggaata ttacacaaaa
    46681 agacaatgca tatattttta caggtgcaac atatctagat gttgatgatt tagaacatta
    46741 tccatttgtt atgatgggag atatacatat agtagatgat tcgctatgta aatattcaaa
    46801 aacagtacta gtattatcaa atcaggaatt tgctaaagta ttaaaagacc aaattatttc
    46861 ttgtatagat gataatatca aaatattgtc taattattct tttgcgatgt taatattacc
    46921 aatgaattta ctatatggta atgacatgaa aataatacat gaatattcaa ataatatatt
    46981 tctgaacttt ttttcaagaa aagacttaaa cttagatact tactttgaag aatttaactc
    47041 aatcgaagat atagctctag cattgaatcc aggtatagag agttatattg tttttgacga
    47101 aggtgaagat ttaactaaaa atctggaaga aagatttaaa agctttattg ataaggggaa
    47161 ggtaccccta ccagcacata aaagtgatgc ttttaaattt tggctgataa tttatggatt
    47221 tataactcag gcattagata ttatattgtc atgtaaagga tttaacctaa ctccttattt
    47281 aagatataga gttacattac aatatgtttt attactaggc gataatgttt ttgatattga
    47341 agatctcagc aatatgttgt taaaatgtaa agtagctcat gtactttatg caatatttga
    47401 taaaagcgaa ataaaaaata tttcctttgt tcaattttat aagaaattaa gtgaatataa
    47461 atttagctat aaagtagaaa atgatatcaa agaaaatata aatataaatc aaattgctga
    47521 aattttaaat aaaaatatta cattgttttt aaattatata taaatttatt tatataatta
    47581 cattccttag ggtacataac agaaaaaagg ctgtcgcact aaaaaatagt gctacgccct
    47641 tttttataca aaaaaataaa gctcaagttc aaaagaacct gggattcctg tataataatt
    47701 gtatgctaaa acaaaatact atacaaattg attatactac ttatggtaat aattatcaat
    47761 ttaaattacc actaaatatt gattatatga ttccaaaaga tgctatattt gttgatggta
    47821 caaaaataga gtcatctgcc aatagatata cttttgtttg gaaaaaaact ataaacaaaa
    47881 atatggttag agtgatgaat gatatatcta atttcatatt aaaatgtggg attgattttg
    47941 gtattaaaat aatttataga aataaaatca aaatatatca tttaaaaaaa cttttaaaga
    48001 agcttaaaaa aatatcaaaa gaatcaaata taacatttgt tcatggaaaa ggaaagaaaa
    48061 aatctattgt tcaaaaatct atagcgaaat taaataatta tatcgataga ttgaaaaaat
    48121 atactaaaga ccttcatata atgggtgaac taaatagtta ttctaaaaca gataatgacg
    48181 caactttcat gagaatgaag aaagaccata tgaaaaatgg gcaattgaaa ccagcatata
    48241 atatacagtt tggcgtagat tcagaataca tagtttgggt aagttcagag cataaaccta
    48301 ctgatactac aacatcaata ccatttttaa aatctattga agagcataca aaatttaaat
    48361 atcctaaaat agtagctgat tctgggtatg aaagtgagga aaactataca tttttagagt
    48421 gtaataatca attatctttt ataaagcctg caaattatga aattagtaaa actagaaaat
    48481 ataaaaatga tattgggcgt attgataata tggattatga tgaaaaaaaa gattattata
    48541 tttgtaaaaa tggcaaaaaa ctatttgcta ataaaataat caatagaaaa tcaaaaacag
    48601 gatataaaag taaaataact tgttatactt gtaaagaatg ctgtgattgt caatataaaa
    48661 acggttgtat taagggaaat aatagtaaga ttcctcttga aaatagaact aaaaatttac
    48721 aagtatctaa gttatttcat gaaaaaagaa aagaaaattt aaagagaatt ataagccaag
    48781 aaggttgtca acttagaatg aatagaatta tacaagcaga aggaactttc gctcaagtaa
    48841 aacaaaatat gaaatttaga agatttttaa gctgaggcaa agaaaatgtt atatcagaat
    48901 gtattattgt agcgatagct cataacattt ctagactaca caacaaaata ataaaaaata
    48961 aatgtggaat atatcttcat catttaaaag aagtattcta aatttattat ttatagttag
    49021 atattatctg aaaaaatggt atttttatac ctttatttgt tatgcataat tttacttaga
    49081 acataagctt tatataaaac aattaaaaat atatctaatt aagataagta aaaaaagcta
    49141 tcacagaaca aatttaattt gctaatgcga cagcccattt ttgttaattt gacacttaat
    49201 aatattaaaa taacaaaaaa gtattgaaag tatattgcat ttaaggtaga attaaataaa
    49261 atattataac attataatgt ttatatagtt gttaataaaa atttggagga aaatatatga
    49321 taaaaataat gttggcctgt tcagcaggga tgtctacaag tttattagtt actaaaatgg
    49381 aaagtgcagc taaagaaaat ggtatagagt cgcaaatttg ggcaatacca gaatcaacta
    49441 tacaaaatga aatagaaaaa tgtgatgtat tattactagg accacaagtt agatatgtat
    49501 tacctaaggc tcaagaaatt gctaggccat ataatatacc agtagaagtt ataaatatga
    49561 tgcactatgg aacagttaat ggagaagctg ttttaaatag agcgatagaa cttaacaaca
    49621 ctaagtaata taaattataa tgtattttta atatataaat tgggagaatc aaaggatgga
    49681 tgaaaagatt atagaaatat cttttaatat aataggttat gcaggtgaag gtaaaggatt
    49741 agcttttgaa gcaataaaag aggctaagaa tggaaatata gaaaaagcaa aagaattatt
    49801 aaaagagtct agggaagtta taaataaagc acatagatat caaacagaat taatacaaaa
    49861 cgaagctagt ggaaacagga ctgaaataag tgtcatactt atacatgcac aggaccactt
    49921 aatgaatggc atgaattttc aacagttagc tgaggaaatc gttgatttac atttgaaatt
    49981 acaagataaa taaaaattaa agataataaa ttaagagagt tcttaaaaga tacattatgt
    50041 gtagcacact aattgttaga ttattgattc aatatttagt gagtaataca ttaggattat
    50101 tttgaggact ctttttatat ttagtttaaa gttaataaat atttattatt aataatataa
    50161 gattatatgt tataatatta taacatataa tttaagaggt gaatcatgtt aagaaatcaa
    50221 ccattatata tacaagttgt agatatatta aagcaaaaaa tattaaataa cgaatataaa
    50281 attgatgaaa atattccaac agaaagggag ttagagcaag agtttggagt cagtaaaatt
    50341 actattagaa aagctattga gatattagaa tcagaagggt atgtagagaa aaaaagtgga
    50401 aaagggacaa aagtaataag taatagtctt tttaataagc tatcaaaagc agagtctttt
    50461 tcaagtatac ttttatctaa aggtcataag ttatctaaaa agactatttc aattgaaaaa
    50521 ataataaatg atacaaattc acaagtattt agtatatttg gagaaaaatg tagcaagatt
    50581 actagaatgt attacttaga tagtaagcca tatatatttt ttactcatta tattcctttt
    50641 gatgaaaatt taactgttga aagttttaat aatgaaagtt ctttatatat gtacttatat
    50701 aggagaaata taaatataac tagatttgaa gatgaatttt ttatagaaga atcagaacta
    50761 gaggtatcaa aggctctaaa tctagctaaa gacatattat taggaagaaa aagaaagacc
    50821 tatgatgaga atgataatat agttgagcta tcatttgcaa gatataatac agaagtacaa
    50881 aactatgtaa ttaaatacga aatataataa gaatcctgag tttattgaaa tgataatatg
    50941 ctcaggattt ttgtttagtt gtaaaaacaa aaaaatatta taacattata atgtttacaa
    51001 ccaaacatta taatgttata atatttttaa taaataagtg atattatcaa ttacataaaa
    51061 attagtttat gttatgaaat cgttattgca ttataaataa atgataatat caataataca
    51121 gggggataac tatggaaaaa ttcgcaagtt ttttagagcg caagattatg cctgtagcag
    51181 cgaagataag taatcagaga catatgagag ctgtaagagc aggtataata gcaacattac
    51241 cactaacaat agtggggtca tttttcacaa tattattaaa catacctatt gatgcttata
    51301 tggattttat agctccattt aaagcaatat tagatatacc atttagatat actgtaggat
    51361 ttttatctct atatgctact tttgggatag catcatcact tgctaaaagc tacgatttag
    51421 atacaacagg tgtcggtatg cttgcagtta tggcattttt agtttctaca atagttccaa
    51481 ctcaagtagt tgaaccagta ggtggagtta tagaagctgg tagatggatg gatatggcaa
    51541 aacttaattc gccatcatta tttggagcta tcgtaacatc gttaattaca gttgaaatat
    51601 atcgttttat gaaggaaaag aatattacaa ttaagatgcc agcaggagtt ccagtagagg
    51661 tttcaaattc atttactgca ttattaccga cagcagtaat tttaatgtta ttctgggtaa
    51721 taagacatat tttaggattt gatataagtg ttgcactaag cgctatgtta tcacctttaa
    51781 aaggattctt atcaggaaat agtttaggtg gtgggttact gacagtattc ctaataactt
    51841 tattctgggt acttggaata catggtccag ctataatggg gccagtaata agacctatat
    51901 gggacatgtc tatagcagaa aatataactg cattcacaga aggagtatca gctcatgcaa
    51961 tgccaaacat atttacagaa caatttttac agtggtatgt atggataggg ggagcagggg
    52021 ctactcttgc attagttgta atgtttatgt tttctaagtc acaatatcta aaaagtttag
    52081 gtagattagg atttttacca gggttattca acataaatga acctataata tttggagcac
    52141 caatagttat gaatccaata ctagggatac catttataat tggacctata ataatgacaa
    52201 ttctatcata tgttcttact attacagggg ttatacctat gatggtagca agattaccat
    52261 ttgcaatgcc agcaccaata gcagcagtaa tgagtactaa ctggagtata ctagcaggta
    52321 tcttagtatt aatcaacttt gtgatatcat ttgctgttta ttatccattc ttcaaagttt
    52381 ttgaaaaaca acaattacaa agagaacaag aagaaatgag tgaaaattta taaaaataca
    52441 tagatataga ggttttgtac tatataaaat atagaaaaag cttataagtt attaagggtg
    52501 aaggtaggag gaatgacctt tgcctttaat tttatatatt ttaaataatg taatttgagg
    52561 aggagaaaga tggaaagaag attaggaata tcagtatatc cagagcatag taacatggaa
    52621 gatgataagg catatataaa aatggcttca aaatacggat ttaaaagaat atttatgtgc
    52681 atgctttcaa ttacaagacc taaggaagaa gttaaaaaac attttaaaga aattataacc
    52741 tatgcaagag aattaggatt tgaagtaatc cttgatatag ctccaaacat atttgatata
    52801 ttacaaatat cttatgatga tttaacattt tttagtgagt taaatgctag tggaataagg
    52861 cttgactatg gatatgatgg aagtaaagaa gctatgattt ctttcaatcc atatgattta
    52921 aaagtggaac taaatatgag taatgatgta gcatacttgg ataatataat tacttacaag
    52981 ccaaatgtaa ataatatata tggttgtcac aatttttatc ctcaaagggg tacaggcttg
    53041 ccatatgatt tttttgtaag atgttcaaat agatttaaaa agtatggaat aagaactgct
    53101 gcttttgtta attcaaaata cgcaacaata gggccttgga atataaatga tgggctgtgt
    53161 acgcttgaaa tgcatagaaa cttagatatt gctacagcaa ctaagcactt attcgcaaca
    53221 ggattgattg atgatgtaat tgtagggaat gcatatgcaa gtgaagatga attaaaaaga
    53281 atgtctgaag taaatgaata ccaagttgta tttaatgtag tagctgaaga aaaaacttct
    53341 gaagtagaaa agataataat ggtaaatgag caacacttta gaagaggaga tataactaat
    53401 caggtagcaa gatctacaga agtaagaaaa aaatatgcta aagaaaattt ccctaaacat
    53461 gataataaga acctctttaa aagaggagat gtagtgattg gtaataatga ctttggaaag
    53521 tataaagggg aattacagtt gatacttcaa gattgtacag atgaaagaaa aaataaggtg
    53581 ggtagaataa aggaagacga aataatactt ttagacttta ttgaaccttg gagtaaattt
    53641 aagattattt tagagggaga gtaaagtgaa gatagacata ttaataaaat gtggaaaaac
    53701 agtagataaa agtataattg atatagctat attagacgat aaaataatag aagtaaaaaa
    53761 tcagatagat gattctaagt atcaggcaaa acaaattata aacttagatg gagagaaatt
    53821 tattagtgct ggttggatag atatacatac gcattgctac gaaagactag acctttataa
    53881 ggattatcca gatgaggttg gaataaaaag tggagttact actgtagtag atgcaggaac
    53941 aacaggagct ttagatatag gtaaatttta tgaagatact aaaaaatata aaacaaatgt
    54001 atatgcttta ataaatattg ctaagcaggg aataacatct caagatgaac tttcaagtat
    54061 gatgaatatt gatgaatatg aacttaaaag agcagttaaa aaatacaaag attttgttgt
    54121 tggaatcaaa gctagaatga gtaaaagtgt tgtaatttca aatgatgttg aacctttaaa
    54181 agtagctaaa agaataaaaa atgaacttaa tctacctatg atggttcact ttgggagttc
    54241 tcctccaacg atagaggata tatttgacta tatggaaaaa ggagatatat taacccatat
    54301 atataatgga aagccaaatg gaatacttag aggcaatgag gttaaaaaag aaatcataga
    54361 agctagagaa agaggtataa tccttgatgt aggtcatgga accgaaagtt ttagtatgga
    54421 tattgcaatg aaatctaagg atgcaggaat ttttccagac actataagta cagatatata
    54481 tattaaaaat agaataaatg gtccagtgta taatctatct acaacaatgg aaaagtttat
    54541 atatatgggc tattcacttg aagatataat aaataaagtt actaaaaatg cagcagatgc
    54601 aataagttta aaaaataaag gtttaataaa agaaggatat gatgctgatt taactatatt
    54661 tgatgtggtt aatgaagaaa aagaacttca agattctttg aataagtcag taatcacaag
    54721 tacgtctata aagccaagag cagtagtagt caatggagaa tatttaaata taggtaagtc
    54781 tatagaagag aatgagtaga agggagaaac tattgtatga gtagtatatt tgaaaaatac
    54841 tctgtaagac gtgttataaa tgcttcaggc aaaatgacta tactaggagt atcaacagta
    54901 gataaggaag ttattgaagc aataggtgaa gggtgtaaaa atttctttat aatagaagaa
    54961 cttataaata aaacaggtga atatatagca aatttattag ggtgtgaaag tgcactaata
    55021 gtttctagtg catctgctgg gattgcacag agtgtgggag caatgatagc aaaagatgat
    55081 atgagtctag tttacaatgt aaataatcct aagaaacaag ttaaaaggga aataataatt
    55141 ccaaagggac ataatgttga ttatggagtt ccagtagaag taatgataag acttggagga
    55201 ggagaagttg ttgaggccgg ttatgctaat atgtgtaaca aggaacatat aataagagag
    55261 ataaatgaaa atacagcagc aattatgtat attaaatctc atcattgtgt tcaaaagagt
    55321 atgctaagtg tattagatgt agtacaagtt gctaaagaat ataatttacc tttgatagta
    55381 gatgcagcag cagaagaaga tttaaatgta tattatgaat tgggagcaga cctagtgata
    55441 tacagtggtg ctaaggctat agagggtcct agctcagggt tagtaatagg taagaaaaaa
    55501 tacatagata atgtaaagct tcaatcaaag ggtataggaa gagctatgaa aataggaaaa
    55561 gaaaatattg taggtctaac atgtgcaatt gagagatata taagtaatga taaagtaact
    55621 ttaaaagaaa tggaggacaa gctaaatcca tttatagaca agataaatac tataaaggga
    55681 gtgagtgcta gtataactag ggattcagca ggtagagaaa tacttcgtgg agaaattgac
    55741 tttaatgaag atataataaa taagtcaaca caacaaatta taaatgaact tagaagtgga
    55801 gagatagcta tatacactag agactataag gctaatgaag gcaagattga gattgatata
    55861 agaagtgtaa ctggaagtga tttagatact atttataata ggataaaaaa tatagtagaa
    55921 agttagagtg tagagtaagt gacattataa tgatttaata aattaaattt taccaatgga
    55981 ggggataaat atgaattgta taccacaata ttataaaaat agagtttgtt taaatgttct
    56041 tgcaggaagc ataaaaaatg ctaaagaagt atatgatgct tgtgacgggc atgtattgat
    56101 aggagtacta tcaaagaatt acagtactgt agaagcagct attgaagata tgaaaaaata
    56161 ctcaaaggaa atagataatg caatatctgt ggggcttgga gctggagacc caaatcagtc
    56221 aaatatggta tctcagattt ctaaagaact tcagccacaa catataaatc aagtgtttac
    56281 aggtgtggct acgtctagag cattacttgg tcaaaatgat agtataataa atggattagt
    56341 ttctccaact ggtaaaccag gatttgtaaa aatatccaca ggtccattaa gttcaaaaga
    56401 aaaagatggt atagttccta tagaaacagc aatagctatg atgaaagata tgggaggaag
    56461 ctcaattaag ttttttccaa tgggaggact taaaacaaag gatgaatata tagaagttgc
    56521 aaaagcttgt gcaaagcata atttttattt agaaccaaca ggaggtatag acttagataa
    56581 cttcaaagag atagttcaaa ttgcacttga tgctggtgta gaaaaagtta tacctcatgt
    56641 ttatacatca ataattgata aagaaacagg tgaaacgaaa gtggaagata taggagtact
    56701 ttataaaata atgaaagaat tattgggata gatttatgaa tatattagct tttggtgaaa
    56761 taatgatgag actttcagta cctgactaca agttcttaac acaaaccaat gaactaaatt
    56821 atataattac aggcacggga ttaaatatat tatctggact taaaaacttt ggatacaata
    56881 cctatatgtt gacaaagttg cctaataata atgtaggtaa agcattaagt gcaaatataa
    56941 gaaagcttgg agtaaaagat gactttatca catatggagg gaatcatata ggagtgtatt
    57001 ttcttgaaaa tgggtatgga gaaagacctt ctgaagtgac ttatttgaat aggttaaata
    57061 gttcattttg tgagagtaaa ttacaagatt atgatattga taaatgttta gaaggaatgg
    57121 atatagtcca tatttgtggt attgctatgc aacttacaga ttcagttaaa gagattgctt
    57181 tagaactagc tagaaaatct tatgaaaagg ggataaaagt attctttgat tttaatttta
    57241 gacaatcatt aaatccagaa aggacttatg atgatttagt aaatgattat aagaaaatac
    57301 taccatattg tcatgggctg tttgctagtt atagagatat aaataagata cttaatatag
    57361 atagtctaaa tataaaatct agttcagaat tgattaaaaa agagtatgat ataggtattg
    57421 tagctggaac tatgagaaga tttgatgata tgaataatag atttataaag ggatatatat
    57481 caaatgatga tggttatttt gaaagtaggg agtataagtt agaaatatat gacagggttg
    57541 gtgccggaga tggatatgta gcaggaatta tatattcata tttggaaaat atgaagagtg
    57601 aagatatagt tgagtttggg gttgctagtt cggtgttagc tcatacaact tatggggata
    57661 attctttagt aagcacaggt catgtactta gactgatgaa caatgaaaaa atagatatat
    57721 tgagataata catttgtata taataaaatt tttatctttt ttagacacat ttttgacttg
    57781 cttatatttg ttaaacagag ttatttttaa tgattataaa tattaaatta aaagttaaat
    57841 aataaaatag tagaaaatag cattaactat agaaaaaatg gttaatgcta tttttatcgt
    57901 taatattgat taattttata ttatagaaat gaacttttct aatgctggat ttgtattttt
    57961 tttattccat acaactacaa cttcaattct attttctact tcttttatag gtactattgc
    58021 aatatcacgt tctatcattg tatctgtaac acaaaatgaa ggtaaaatgg atattcccat
    58081 gttagaagat accaatgatt caatagtatt aagattattt gaacgttgta ccacattagg
    58141 tacaaaccct gcttcacgat atctattttg tatcatagat ttttgtccat actcatcccc
    58201 tgtttccttt acaaaaataa atttatcatg ttgtaattca attaaatcga tagaatcctc
    58261 attgtaaagt ggatgaccag gaggtaaaag agctaccaaa gaatatcttt ctacagtttt
    58321 atattcaaaa tcttttaatg gttgattttc tggattaata acaaaagcga ggtccataga
    58381 attatttttt actaagttta aaagttcggt tatttcatta gtacaaatat ccatagatat
    58441 attagggtat gtattagaaa attcttttaa atattgttga agtttgtttt tttcatatcc
    58501 tattaaggtt ccaatgctca aagttccaaa aaaaccatgt gcaaattgtt gtgtttttgc
    58561 aatagcatca ttgatatttt ttattatagt acgtgcctca gataaaaaaa cttttccagc
    58621 tggtgttagt tcaacatgac gtttacttct tgtaaataga gttacattta tttgttcttc
    58681 taaagctttt atttgctgtg taacagcagt ttgagaaata taaaattttt ctgctgtttt
    58741 ggtaaaactt agcttttctg ctacagatat aaaatattct aattgtttag tattcaaata
    58801 atcaccccta tttaaacttg attgtttgta aaccttattt atctataatt aaagcttatt
    58861 atagtataag aaaatttact tttaaagaat attagaaaat atttgtataa aaatatatgt
    58921 tttaagtata tctttacatt agattttata aatttattaa taagaataac ttatatattc
    58981 caatgaaaac gatattggat ttaagtaagt ttgtctcata aaatgaaagt atatcaattg
    59041 ataatacttt aaaataagaa gggagaaaaa atggaagata aattttatgc aaaaggcaac
    59101 ggaaataacg gatatattaa aaatcttgaa gtttgttcct ttaataactt agatggaact
    59161 tgtggaatgt ttcaaatggc tctgtacaaa agagatgaaa aatactattt atatggatgc
    59221 tgttttggag gaaataaaaa aaatggagta atgattagcg atattacaga cccttataat
    59281 ccacaattta taaaacattt tcaaatgtta gaccctaaag agtatcctac aacaacaact
    59341 cccaaaattc aaatagcaga tgatttaatg atagtagcaa tgagttgtgg aagtggacca
    59401 ggagcacttg ttgaccaagc taaattagca aatattaagt gtgaagcagg aattagaata
    59461 tacagtttaa aagaagaccc tttaaatcct aagtttttag gatattggga ttgtggctta
    59521 aagcatgtaa tgggtgttca tagattcatg tacaatggtg gaagatatgt acatttatca
    59581 agtgattgtg ttggctttga aggtctgatt tatagggtca tagatataat aaatcctact
    59641 aatccagtgg aaataggtaa atggtggaga ccagaccaat atgcagatgg atatccaaat
    59701 agaacttttg atgcaggagc acctcattgc ccagaattta tggataaagg atggcttcat
    59761 ggacctccat ttgtaagaga cggaaaagca tattgtggtt atggaggagc tggtttagtt
    59821 gtattagatg ttgaagattt aacaagacca agatgcttag gtgaattgcc atttacgcct
    59881 gcattttcta gtagacttgc aggtgcaaga actcatacag cattaccatt gccaggaaga
    59941 gatttagtcg ttgttcaaaa tgagggagaa agattccagt tctttaaacc agataacatt
    60001 acagatgttc aagctatgaa taatatacat atggttgatg ttagtgaccc aacaaaacca
    60061 acattaattg ctcaatttcc atatcctgaa gttccaaaag atttccctta tcctaacttt
    60121 aatgttgcag gattaggaaa accagggcca tttggtccac ataatcttca tgaaccaatg
    60181 gataataagc catggttaga gcaaagagga gatagagtat attgctgtta tttccatgca
    60241 gggctaaggg tttatgatgt atcagaccca tattatatca aagagctagc atattttata
    60301 ccaccaaatc caaataaaac accagaagaa tcttatttcc caggattccc aggaccacgc
    60361 ttggcagtaa cagaagatct tatcgttgat gatagaggct acatcatcat agatgcttta
    60421 gatgatggat tctatatatt aaaaatgaaa gaagattaaa taaatactaa agagggagag
    60481 ttgaaaatga aaatactagg tatttctttt ggaacaaaaa atggaaataa tgacacaatg
    60541 tgtaaagttg cacttaaagg tgccaaagaa gcaggggctg aagtagaatt tattcaaatg
    60601 tcatctatta acattaaaca ttgtactgga tgttgtgcgt gtgttaaaac tttattatct
    60661 gggaaaggta gtatgtgtgt attaaaagat gattttgaat ggttgcttga caaaatgaaa
    60721 gatgcagatg gtatagtagt ttcagaccct atttttgaag aaggggcatc aggattattc
    60781 catactataa tggaccgttt tggacccaga gcagatagag gaaataacat tataggaaca
    60841 aaagttgcag aagttatagg aggaaaaatt ccagattcaa gaatgcttaa tgataaagta
    60901 atatcattta tgggaatagg aggttctgac tggggtacaa gagttcaatg tgaacatgct
    60961 atgctagctc tcataccaat gtggaaagtt atagataatg cttggttccc atgggcaaag
    61021 gaattagtaa tggatgatac aaggcttgtt caagttcatc aaattggttt aaatatagtt
    61081 gaagcagcaa aagattttga aaaagcttca tatcaaggag aagaaggtgt atgtccacat
    61141 tgccacaata gattattcta ccttgagcca ggtactaaaa aggcaatttg tgctctatgt
    61201 ggtatagttg gagagttaga tactataagt ggaaaaacta tatttagttt tccagaagag
    61261 caattaggtc atgctcatga tactttacca ggtaagttta tacatggtga tgatattaag
    61321 aaaatggaag gtcattatgc agaagttcgt aaaacacaag aatttaaaga aagaaaaaca
    61381 tcttataatt ttatagagcc attaactaaa gaaaagcaag ctggagtttc attaggataa
    61441 taattaaaat actaagactc ttttttaagg gatgttagat gttataggag gcttattgta
    61501 tgaatgaaaa gccaagtttt aaacaaattg aagttatttt agcagttatt tttttggtac
    61561 ttacatatta caaggttaga ttaactccag catttattgt tatatttata ccactatatt
    61621 taagttattt tgcagtatct atgattgtaa atcaaatagc aattaagcta ttggagataa
    61681 ggcaagctag ggaagctact aattacaata taggaaatgg atagaaagaa aaaagaaata
    61741 ttaacactgt ctatggggat tgctttacta cctcctttat gggcagtatt agcaccttat
    61801 ataggaataa aaactggagc tgtagcacta atctgtgcag gattatatgt aactaatggt
    61861 aataaacaaa aagatggatt aaaaataatg tttggttttt ggtgtggaga tttatgggca
    61921 gtgttagcca ttttaattat gggatatatg aatttcaatc aaaacctaga attattttta
    61981 acacttagca tattaggttt ttttgcagtt gtaattgcat ccttatttga aaaaataatt
    62041 ttcctaccat catggctttg tggttgggct ataggtctaa ctgttatgac aggtgaaaat
    62101 attattaatt tacaagatat ttgtattcaa attgctgtag ctatggcagt aggagtatgg
    62161 tacgtgggtg caggtgtaga tttgtttaca atatatattt tgagtaaaga taggaaaaag
    62221 ggaaattgaa agcatgtgaa tatactttga ttataggaga atggctatgg gttttgaatt
    62281 taaaataatg agaagtttaa tatatgtagg acttgccaag gaagaatata gacctaagct
    62341 aatggactgg ttatatcgtc accatattcc agatagtatt agcacttttg gaccatattg
    62401 tactaaatat gccttttatc aagcatatcc tacaccaaat gaaggtgagc gttttggtgc
    62461 acgtaagatg caactaacag aacattattg gcttgtagat gaacatatgc ctgagatggc
    62521 aaatagaatt atgacagaat atatgcctat ggatgttcta cgttggcaag ggtgtatacc
    62581 agatgtagaa aataaaaggg ttcatgaaaa tgtagaaagt ggagatgcag gacgtgcagt
    62641 aggtggagat aatggatgtc caccatttat atttgccttt gttccaataa actgggaaga
    62701 agactttaga ggaaaaggac gtactgtaca agatggacca aactatcgtt ggcaatttat
    62761 gattaagtat ccagatggta tctctaaaga agaaggagaa aaatggttct atgatgaggt
    62821 agtgccatac tttacaaact gttgctatgt taatcgtttt gtcagtagta aaataatgat
    62881 taattatgga gcaactgctt ttgaccgtgt atcagaacta tggtttgaag gggaagaaga
    62941 atggtataaa gctgtggttg aagagacaaa gtcgtttatt aaaaaaccag aatgggcaca
    63001 agaagaggag ttcccatatt taaaaccaca attcaatatc gcatcagtat tcttaggtga
    63061 tatagcaact atggatgcat actcacagta tcgtggatat ataccaatga gataaaaatt
    63121 atagtttgtg ataagtagag gaggcattta ctcttactgg tagaagaaga cttattgtat
    63181 ccttaaaagt aggtgaatat atagttttat atttaaattt atataaaact aagactaata
    63241 aatatgaaac aatagaatta gaataatttg ataatatttg ttaaaagagc atttagaatg
    63301 tgtttaaaga ttaagatatt ccttttatgg tagcagatag ttgaaataat aaaactgtta
    63361 tcatgaaagg aatattttta tgtataggaa atttttaaaa ataaaagtta aatatgttta
    63421 agaacatctt aaagtgaaag aatcattgtt agaaatatgt agacaatata gtctttataa
    63481 cgtatcatat taacaagttt acacttggat tatgaaataa aaagagtaat tccaaaggtt
    63541 gtaaatacta tgctgacttt gatacttcaa agtttaggtg attttgtaat tgttaataga
    63601 aatacgttta atgagcataa agaatttatc taataatagg agaatataat gtatacaatt
    63661 ggacaagtat ctaaattttt aggaatatct agagatacac taaaatttta tgaggacaaa
    63721 ggattagtaa atcctaagaa aaatgatgaa aatggatata gaatatataa tcaggttgat
    63781 atctatgata ttgcaacaat aaacttttat agagaaattg atatagaaat taaaaagatt
    63841 caagaaataa gaaaaagtaa gagtataaac aatttagaac tcttactaga agagaaggaa
    63901 caaatcatac taaaagagat agaatataaa aagcttctct taaaaaaggt tcagttagtc
    63961 aaagaagatt gtgacaaaat aaaaacatat tttggaaaat acacaataaa agaaatgaag
    64021 cctttggaag taaaaggtaa aataaaacat gttactaact atgaggaata tgaagcccta
    64081 aaagagaata caaacaactt aaaaaaagca gttacattaa ctgatttaag aagagtaata
    64141 aattttaatg aagaaggtat aatagaagaa aaatttataa ttgtaaggga agtagatgac
    64201 tacaacaaaa tcatagaagg tgaagttcta tctcatccca attgtattta tactattatt
    64261 gaagatggca gatggtcaac tggaggagaa aatattgata ataaagtgga agacagatta
    64321 agagaaatag caatagaaaa tgaatgtgaa ttacttggaa tagtctatgt taatatattg
    64381 cttactactt atgaagaagg gattgagcgt atatttttag agatttatgc acctataaaa
    64441 taatataaaa gcattgacct gggacttact cataggttta aactcatgat ataagcagtt
    64501 ataacttata tagcaattaa atattaattt gaaatgagga ttacttatga gaacagagaa
    64561 atcattaaaa aggcctatag ccagttttat tattctaaca aatataattt ttttaccact
    64621 ttttttattg gtagtagtga ctataatgtt aaaacttcca acagtgatat ctgacattgc
    64681 gttgtgtata tcagcgtggt catccacttt tgcatttatg atattattta aaaaaattta
    64741 tccagataag aaatttttag tacacgtaaa agatagattt agaaataaac ttaaattttc
    64801 aacagtatct ataataatta gtatacaagt cctaatagct gtagtagtta tatttatatt
    64861 agcatctaaa aatcatggaa taatgcctaa ctttacagtt tcatcatggg gagcatttat
    64921 atatttattt ttaaaaaatt tatttgcagg atcattaggt gaggaattag gttggagagg
    64981 atttgttcaa aatcatcttc agaaaagaca ttctccttta aaagcatcca taatagtagg
    65041 tttttggtgg gggatgtggc atttaccaat atggtttaca acaggattca aaggacttga
    65101 tttaataaaa tatattatat tttttatgat tgcaattata tcaatcagta ttataatgac
    65161 aactttttat aatctaaata aaactttgat aatacctatt gtaatacatc aactatttaa
    65221 ttttttaata gggataatta atggagattt aatagagctt ataaattact atgcaatgtt
    65281 atatttaata gttgcaattg tattggtagc tataaatcca ggaaatgcct tatataaaag
    65341 attttctaaa aacacaacac aaatacttta ataatataag tgagaatcat atcacaaatg
    65401 agagaaataa ttctccttat taattaattt taattaataa atattacaat agatttatct
    65461 ggaatggaag gtatgcagag tgtatttcat tagatgaaac acttaaaaga atgaaataga
    65521 taagtatcaa cttattatat gagagaaact ttaactttct tggtttaaaa tattaaaatt
    65581 ataaggaaca tttattatta aatactttat ttatatgaat taattgaaga aaaaggatat
    65641 taaactacaa gttaaaaaat aaatttaata tattagaatt ataaataagg cacattaatt
    65701 ttattttaaa ttaatgtgcc ttttatttat ggtaatttat gcataattag tatcgttttg
    65761 attctttaaa taaatttttc ttggtttctt cacataagga acttttttta atttataaaa
    65821 tctacagtta tattatagta tctattttag agaagtttaa tttttgtatc aatctaaaac
    65881 aaaagttata cttaaatgaa attgaaaacg ataaaattct caaataaaat aagtattgtg
    65941 gaggtgatga aagaatccaa tgataatatg aagactaatc ttaataagaa agtaggggtt
    66001 aatggtagtg gacaaagaaa ttgtatcaat tctccagatt ttattaaata gcacattgat
    66061 tacaactaat ggattacaag aggagtctaa ttcatcaaag agacaaatta cttatagaat
    66121 aaataaaatc aatgacatgc ttaaagtaaa aaatgtacca cttatatgtt taagagctga
    66181 taaagatatt atcgttagaa aagaaacaaa aaaagcaatt aaagaaattt tagaaaaaaa
    66241 ctattctaag aatacttatt attttagtaa gacagaaaga cttttatata tgtatttaat
    66301 gctttttatt aacatggagg atatttcaat taatcatttt ataaattcta taaaagtaag
    66361 taggtctact gtaaatcttg atttcaagga tttgatacca aagcttgaaa agaagaacat
    66421 taaagttaag aacaatcgta taaatggata ttacatagtt ggcaatgaga tggaaattag
    66481 gagagtgctt attaaaaata ttatagaaac tttgtctaat gagaaaagtt caagggtatt
    66541 tgatattttt attaaagaat ataatttaga tagttttgaa gaggctaaaa aaattatatt
    66601 aaagctaata aaaaaatatg aaattacttt tgttgaagat agattaatag aatttatata
    66661 tatatttatc tttctaaagg caaggatgta ttcaactaga atagttactc aggaaaatgt
    66721 agatattcct aatatttcag ttatgagttc aatgaaggag tataaatttg ctaaggaatt
    66781 attagaagta tatgggagtg aagataaaat aaagcctcac aatataatgt atattagtgc
    66841 ttggatttta ggtatatcag taggaaatta tgaagaagat acagaagata aggatgtaat
    66901 ttcaaaaatt gtaaataaaa tgatgacaaa gtttggatat ttaagtggag tttactatat
    66961 aagccaagaa aaaatattta aacaattata ttctcatttt agacctgcct actatagact
    67021 tttatttaaa ttacctatct ataatccgat ttgtgaaaaa gtaaaagaag aatataaatt
    67081 agtttataga attgtaagta atgcaatgaa agagttttgc ggattatttg gagaagaaat
    67141 tcaggaagaa gagttagcat atcttacaat gcactttgca acactttttt caaataaaaa
    67201 agaatttgat ggttttagaa aaagaatagc attaatagtt tgttcaaatg gcgttggtag
    67261 ttcagctatt ttacatgcag aacttacaaa cttatttcct gacttacact ttataccaat
    67321 gtcggaatca gttggattag aaaatataag tgaacctgta gatattgtat ttactactaa
    67381 ttataacgca gagggtttaa aaacagatgt accagtaatt aaagtaagcc ctgttatgac
    67441 cacaaaagaa aaatataaga ttacacgtga agtgtatatt caattaggtg atattttttt
    67501 aagacaacct aaaatagatg aggttatgga tataataaaa aaatatgcaa atgtaacctc
    67561 tgaaagtatt ctttcaagtg agctattagc ttattttaca cagatagaga attttacatc
    67621 taaggaagga gaggggccta tgctaagtga gattactaat gaaacactag taaaaataaa
    67681 ggtaaaagct aagaattggg aggaagctat tagacagtca gcttctgtat tagttgaaaa
    67741 taacaaagta actgaagggt atgtagatgc tatgattaac tcagcaaaag catctggacc
    67801 atacatagta attacaaaac atgttgcact tccacatgct agaccagaag ctgggtcaaa
    67861 agagattgca ataggcattg ctactttaga tagtcctatt gagtttggga ataacgaaaa
    67921 cgaccctgta aaatatgtat tttgtctaag tgcaatagac aataatagcc atttacgtgc
    67981 tatgtctgag ctagttgaac tattggaaga agatgagttt tttaaggttt tagatagtgc
    68041 taaagaagct aaagaaatta ttgattttat aaaaacacac gaattataaa ggaggattta
    68101 attatgtata aaattttaat cgcatgtaga gcaggagttg gctcaagttt aatgttaaaa
    68161 ataaagactc aacaaattat taaggaaaat aactttccaa ttgaagtaga acatggttca
    68221 ttagattcac taaatggatt caatggagat gctgtagaaa cattaattga tgttgctgaa
    68281 gaattaaaaa ataaaaattt gaagtttgat ataattggga ttcacaatat tgttgaccgt
    68341 aatgaaataa agacagcact agaaaaattc cttgcttcaa aagagggata aatttaagat
    68401 gataaggagg aatatttatg gagtttatta ttagtttgct gagtacacct gctgttttgc
    68461 ttggcgtagt tgcatgtata ggattgattc ttcaaaagaa atcagctgtt gaagtattta
    68521 caggctcttc aaaaacactt atcggttttt tgatatttgg tattggtgcc tctgctatga
    68581 caggagcact tcaaaatttc aataaactgt tccaacatgg atttggaatt actggtgtta
    68641 tagcttcacc agaagcagct acagcacttg cacaaggtac atatggtttt gcagtttcat
    68701 gtacattaat tcttggattc atattaaatt tagtatttgc acgtattaca aagtttaaga
    68761 atattttctt tacaacaggt catagtttgt tcttttcttg tgtattagtt ttaattatga
    68821 aagcacatgg atttgataat acaatcacta ttttaatagg aggaactatc ttagggttta
    68881 tgtctgctgc actacctcaa ttctgtcaac catttatgcg tgaattaaca ggcggcgacg
    68941 aacaagctat tggtcacttt aacatgattg gttatggttt atcaggttat attgggcgtt
    69001 tattttcaaa acataaagat gatacaacag agactataga atttcctaag tggttatcaa
    69061 tattcagaga cttcttaatg ggtctatcca tagttatgtt aatcttattt tatattgcaa
    69121 cattaaaagc tggtcaagca tttactcaag aaattgctgg ttcaacacat tggttggttt
    69181 ttccgcttat agaggcattt acatttgtgg caggtatgtc aatattgatg tcaggtgttc
    69241 gtatgttctt agctgaaata actgcagcat ttgtaatcat ttcagaaaag tatattccag
    69301 gttcacgtcc tgcgctagat gttccaaccg tatttccata tgcaccaaat gcagttatta
    69361 ttgggtttat atcagcatat gctgctggtc tattagcaat tgctattatg gcatcatttc
    69421 ctagtatatt tcctgtagta attattccag ctgctcacat atgttttttc tcaggaggta
    69481 cagctgcaat atttggcaat acttcaggag gatggagagg ggctattgct gggtcatttg
    69541 ttgtggggtt attacttgca tttttgccag ttatactata tccagtttat gggactcttg
    69601 gtatagaagg agcaactttc cctaatattg attacaacgt agttggttcg atattacata
    69661 atattttaca atttataaaa cctatttaaa ctaaattata taaaagtata gtcatagtta
    69721 ctatgatttc aaggaggata catattatgg aaaatacatt atctgaattt ttagataata
    69781 tatctaatga attgtcagaa tttattgcct caatagatga gacatctata aataaagcat
    69841 gcgaattaat tcttgaagct gaaaaaaatc acggacgtgt acatgtgact ggtattggca
    69901 aaccaggaca tgtatcggga tatatttcat cattgctttc atctactgga acgtcagcat
    69961 atatattgca tggtacagaa gcagtacatg ggtcaagtgg tcaagtagtt gaaggagatg
    70021 ttgttattgc aatatcaaat agtggtgaaa ctcaagagtt aaaagcaact cttaagactc
    70081 taaaagtaaa tggagcaaag ataattggtg taagtggtaa tgagagttca tttttaaaaa
    70141 atatttctga tatattcctg tttgcaggtg ttaaacagga aggagattgt ctcaataaag
    70201 ctcctcgtgc ttcaatttta gctgaaacaa taatattaca atcattaagt gttgtattac
    70261 aatatgctaa aggtcttaat acacagcagt atttgaagtg gcatccagca ggaagtcttg
    70321 gaaagtctat tagagaggga atataatttt atgaaatata aagggattat atgtgcaatg
    70381 ataacaccat ttgatgaaaa tcaaaatatt aattcacaag caacatgtca attaattgat
    70441 tatttgattg aaaagggaat ttatggatta tttattttgg gcactaatgg tgaatgtcat
    70501 gtattaacag atgatgaaaa agttgaattt gcaaagattg ttattaatca tacaaataat
    70561 cgtgtacctg tttttgttgg aacagggggt aattcaactc gtgaagttgt agatttatct
    70621 aagagaatgg aagcgattgg agcaagtgca ttatctatta ttacaccata ctttgttaca
    70681 ccaacacaac aggaattaat cttacattac aaaactattg ctaattcagt taatttacct
    70741 attataatgt ataatatgcc aggtaagact ggaattaata ttgaaccaga gtcagtacgt
    70801 gaattatcaa agataaagaa tattgttgga attaaggata gtagtggtaa acttgacaac
    70861 atgaaagctt atattgaagc aacgaagaat gagaatttta gtgtgttttc aggctcagat
    70921 tcacttattc tggatagtct aaaagctggt agtcaaggag ctgttgcagc aacaacaaac
    70981 ttcctcacag agattggtat ctctatctat gaaaacttta tgaaagggga tttggaagaa
    71041 gctcaaaaag ctcaaagtag tatagaagaa cttcgacgta tactgaaact tggaacaatt
    71101 ccatctgtta tgaagaaaac tattgtcttg aatggaatta atgttggaac tgcacgactt
    71161 cctgtaactg aaccaactgg ggaagtactt gaagaaatta aacgagtagt tgaaaattat
    71221 aggacaatac ttaataaaag tagtgagaat agataatata aatagggaaa ttacactggt
    71281 atataattaa tatatatatt ataaaacatg actaaaatta atgaataagt aaagtggttt
    71341 gatgagtata gaggtgataa tatgaaaaag atgaatataa ccaaaagaat gtcagaatgt
    71401 ggggctcttg caattgtaag agaagaaaat cttaaccgtg catgtgaaat tgctgaagga
    71461 tgtataaaag gtggtataac agttatagaa atgagttata ccctaaataa tgctggagaa
    71521 ataattcaag ggcttaataa aaagtatggt gaaacacttt gtgtgggagc aggaacagtt
    71581 ttggatagtg aaacagctcg tcatgctata ttacatggag ctcaatttat tattgcacca
    71641 aattacaatg aaggtgtagc gaagatttgc aatagatatc agattcctta tgctccagga
    71701 tgtacatcat tgactgaggc agtagatgca ctaagtttag gagcaacttt tataaaagct
    71761 ttcccaatat cagatttcta tggacctaaa ctagtaaagg tatttaagac accaatacct
    71821 gatatgccag ttttagcaag tggagggatt aatattgaaa acctacatat atggttagaa
    71881 aatggagttg atgtatgtgg atttggtggt ttattaacta aaggttctgt tgaagatatt
    71941 gctaaaaatg ctaaaaagat tcgtgaaatc attaaaaatg taaaaaaaat ttaacatagg
    72001 gctgtatcat agtatcttat aattactatg atacagcctt tttaatatta ttcaaattta
    72061 aaacagttta catttctatt atattacata taatttcagt aattttatat taatttttct
    72121 atctggaaaa aaatgattta aaacttaagt tatgatataa tttcattaaa agaaggcgat
    72181 ttttagtaaa tatgagaaaa taatgtgttt ttaggggaaa agttaaatac agatttaagt
    72241 gaacaagaat cgataattaa gatattaaat ggtgaatagg gcatcaaaaa aattactaaa
    72301 ttaaaagttt tagagggaga atcttagcaa gtgtgtgtga aaattcaatt tcaaacaaaa
    72361 aataattgta aatgaaatca atttatacac gttgaagatt cacttttatc attatattaa
    72421 aaagcagagt gaattaaaag tgagtctaaa gataggagga taattaaaac aatgaaagaa
    72481 gacattgggt tacatcgaat gtgtaaaaaa gaacaagcaa caaagaatga agttatatca
    72541 gaggatattc taaaatctat gagtattggg gtcagtaaac attttttaga tgattcattt
    72601 acaataatat ggggaaatac atcattctat caattattag gatatacaga agaagaattt
    72661 ttagttaaat tttctagttt aaaagattat tatgaacaga atctttatca ttttgaatct
    72721 atgaaaaatc attttttaga ggcttatcat catggcgaaa agagtataga atatcaaatt
    72781 tgcatttcag caaataatgg agaccctgtt tgggtaataa tgactggtat attaattgaa
    72841 tcacaagata atgagaaatc aatggtctat atattgtatt caaaaattaa tgagttaaaa
    72901 ataaagcaag aagaactatc tgatatggaa aaagagagta cagagaattt taaatggatg
    72961 atgtcagagt atgctgggaa tgtttatatt agcgatatgg atacatatga attactatac
    73021 ttaaataagc actcatgcaa tactttacag gcatcagcaa atgaacttat tggaagaaaa
    73081 tgttatgagg taattcaagg tagaacttcg ccatgtccgt tttgtacaaa ttcgtattta
    73141 aaaaaagatg acacatatga atgggaattt tataataaaa aactgaaacg aacatttata
    73201 attaaagacc gtatgttgaa ttggcaaggg cggagagttc gtattgaatt atcttatgat
    73261 atgtatagtg ctgaatataa attagcaaaa aaagatcagg aaagagaatc aattttgaaa
    73321 actattccag caggaatggt tagattagat gcaagagatt atcttactat actttggtgt
    73381 aatgatatat ttttgaatat gattgaatat acaaaggaac agtttgcaga ggaacttaat
    73441 aatcaatgtg gatatttatt ttctgaagat tataaacgta gtaagaaact ggcacaagat
    73501 ttgaaggagt ctggggataa tattgtattt gaagcaaaaa tatatacacg ttcaagggaa
    73561 gaacgtatat ggactgttac attgtgttat atcagtgggg aagacagttg ggatggaata
    73621 ccatcttttt atagtatagg tattgacata acaaaggaaa gaaaacagat tgagaaatta
    73681 cagcatatat cagagaaaga tgcattaaca ggaatttata atcgtgctga gactgaaagg
    73741 cagattaaga aatattttga aaaaaattta aatgttatgg gtgcactgtt tatgattgat
    73801 acagataatt ttaaacagat taatgataca gaagggcata tgattggaga tatagtactt
    73861 actgagatgg catcaggtat gaaaaaaata atgcgtgaca gtgatgttgt tggaagaata
    73921 ggtggagatg agtttacaat ttttatgaag aatatttcct cagttaaaga tgcagaaaag
    73981 aaagcagaag aactattgta tatgttccgt catctatttc agaaagaaaa aagttttcta
    74041 aaagtaactt gtagcatagg aatagctata tatccaaagg atggtactac attcaaggaa
    74101 atatatgcaa gagctgataa agccctgtat caagcaaaaa atatgggaaa aaataattat
    74161 gtaatctaca accaagatta ttttaaagaa ttagaagaat ttgattgttc ttctcttggt
    74221 acagttattg attcagaaaa acaatacgct gaatatcctg ataatcttac acgttatata
    74281 ttccgtatgc tttatcagac tgatgatata gaccaggcga ttaatatgat acttgaggtt
    74341 gttgggaaac agtttgatgt aagtcgtgtt tatatttttg aaaatacaga agatggtaga
    74401 tatacttcta atacttatga atggtgtaat gaaggaatct cttctcaaat ggcttatttg
    74461 caaaacagca attatcaaga ctatgaggat tatgaaaagc tttttgagga tgaattagtt
    74521 ttttattgtc gagatatcca tacattaagt cctaaactag aagaattgtt ttctagtcaa
    74581 ggtatccact ctacacttca atgtgcatat aaagaagata gagttttcag tggatttgtt
    74641 ggatttgatg aatgcacagg actacgtcta tggtcacaag aggaaataag tacattatca
    74701 ttgatttctc aaattatatc aatgttttta caacgtaaaa aaaataataa acttaatcaa
    74761 cagattcaac aataccagaa tattttagat aatattgacc agtgtatttg tgtgattaat
    74821 aaagaaaata attttttatt atatgtaaat aaaaaattta aaaatacata ttctaaattc
    74881 caaattggac aaccttatta tcttgattct atagatattc ataagatatc cattatatgg
    74941 aataaaaaag aagcatacct atgtactagc atgatttaat ggtaaagtaa agtttatatt
    75001 ggacttaaat taaattttgt tttaaataag atattatttt agttgattac tgaaaagact
    75061 agaatctata ttaatgaatt atactaattt tgtaccacta ttaaaatatt gtttgctaaa
    75121 aataaaaaat agccttaaaa cagttgatta taaaaaatta actgttttaa ggctattttt
    75181 atctttgtga cgaaatagac acttgccatt tagaatgtga caatatagta gttgtttaga
    75241 aaaggcacaa agcattatac tttaactaaa gtaaaatgta ttttgctttt agaataaaaa
    75301 caattaggag ggagctataa ttgaaaaaga taatatatgt attatttaca attgaactat
    75361 taatagtatc tttattaggt ctaaatatag ttaaagataa tgaaattaat aatattttat
    75421 ataacgatac aacaagtata tctgtaatgt ttaaagatta taaaaggtta aataaaaatt
    75481 atagtaagtg gattaaagat attgcagatg aaaataatgt gactatatca aagtatgttt
    75541 ttaataataa tgaaaaatta tctatatata cgactgatac aagtttgaat aacaatataa
    75601 agttaaaatc aggaaaattt cctaatacta attcaaatga atttattagt aatataaaca
    75661 ctaataatag taatcaagta ggtaaattct caactatgag taaagacata tcaattttaa
    75721 ttagggattt tggtaaaata agtgaagttg gagaatcagg aatcttatat atttcaactc
    75781 aaaatgaaga tacaataaat aaaatattaa aagagttaaa tgtggacaga agtattttta
    75841 tagcaagatt acatgataga tatgttaact caaatttata cttaaatcct tcaataatta
    75901 gagatttaat actaattatc ctttgtttct tggctacaat aatacattat tcaattagtg
    75961 tgagtagaga ggcttctatt ttaagattaa atggatactc taagctagat ataattgcta
    76021 gagttataaa aaatatactt agaattatga ttttatcatc tgtcacagca ttattaatat
    76081 atataatcta tattttaaaa ttaaatatag gtgttagagc atgcttatac tttgctatgt
    76141 tttcgattat atgtattttg ataaatattt tgatatctat attaatagtt ggttttaata
    76201 gtagaagttc taaatatatg ctatctctaa atggaaaaaa atcttatggt tttgtaaata
    76261 taatgcattt cacattgaaa attgtattta tatcatttct tatattatcc ataaataact
    76321 gtattttaaa ttataatatg ctacaaactc agttaggaaa tctatctgag tgggataaag
    76381 caaaaaatgt ttataatctt actcttaaag atacaggtga acaatcttta ggaaaggaag
    76441 aagtaattaa aaatgccaag attaaaggtt tctataaaaa tttggtagaa gaaaaagatg
    76501 ctttcttaat agattcaact aattttgaaa aacttgaaga tggaagttac atgtatgaaa
    76561 taaattcaaa gggtaaaaac ccagaagtaa gtcaatatgg taaaaatata aaaataaata
    76621 aaaactatct taaagttaac cctatttact caaatggcaa agaaatattt aatctaatcg
    76681 attatgacga taagactata aatttattag ttcctaaaaa gttacaagta catgaaaatg
    76741 agattaaaaa agagtttaga gaattatttt attttgaaaa aatagaagta gaaaatatgt
    76801 acaataaaga gttaaataga gagttaaata aaacaaagaa gtcagattta aatgttaata
    76861 taatatatgt agataataat caaagctatt ttacttataa ctcccttgtt atggatgaca
    76921 ataggaatct cattgatgac ccaatagcaa tagttgacat agataatatt gatgattctt
    76981 tttatctttc ttatatatct agatgtgtat attttaattc taagaaatta gatgcccttg
    77041 cagatataag taacattatt gaagctcaag gtgtagaagc gcatatccaa agtttacatg
    77101 ctgtttataa tgagtatggt ttagaaataa ataaactaga aaaatatttg aatagtgaaa
    77161 tttttactat aataataata gcaatatcaa acttaatgat tacctacaat atagtagcta
    77221 gctactatga aagaaataaa tataagttat atattaaaaa aatatttggt tattcagcta
    77281 cagctagaag tatgttgtta atagtctcat taatattaac aaacattatt ccaataggca
    77341 ttatatcaac aagagtagat ttaagtaata atattatctt atttggactt ctaatattag
    77401 ttatagaagt aattgtatct attgtattag acaagattat ctcaaatagt tcatttaata
    77461 aaattataaa aggagaacat taaaaagatg atttcattaa taaatatatc taaaaaattt
    77521 aaagataaat ctataataga caaatttaac ctagaaattt ctaagggcga gtttgtagcg
    77581 ataacaggaa atagtggttc aggtaagaca actttactta atataatggg attattagaa
    77641 aaacctaatt ctggtgatat tataataaat aatataaaaa atccaaatag taaacagata
    77701 agaattttac aaagggattt ttatggctat ctatttcaaa attatgcttt aattgagaat
    77761 gaaaatgttg aaaataactt gaaaattgct ttaaagtatc aaaaaaatat caaccataat
    77821 gaaaaaataa attacgcact tgagtctgta ggtcttagaa aatacaataa aaaaaagata
    77881 tacgaattga gtggaggaga acaacaaagg gtagcattag caagagtaat attaaaagaa
    77941 tgtgaagtaa tatttgcaga tgaacctaca ggtaatttag ataaaaaaaa tagagacata
    78001 gtatttgata tacttaaaag tctaaataag aatggtaaaa ctatcgtatt tgtaactcat
    78061 gatttagagt tatcggagca ggcagataga gttataaaat tgtaataata tcaactataa
    78121 taaatataag aaagagatta cagctaaatc aagtttaata ataatacgaa tagaatttaa
    78181 acattaagta aattagtagt ttgtaaatat aagtataata tgatatcata aaggctcaaa
    78241 agaaatttta tataataaga aatctaaaaa taacaaatgg aggacatata aagatggaaa
    78301 atttaccaaa ttgcccgaaa tgtaattcag aatatactta tgaagatgga actcttttag
    78361 tttgtccaga atgctctcat gagtgggcat taggattggg agctgaagaa gattcaaata
    78421 ttatcaaaga tgtaaatgga aatgtattaa atgatggaga ttctgttaca gtaattagag
    78481 accttaaagt aaaaggaagt tcatcatcta taaagattgg aacaaaagtg aaaaatatcc
    78541 gtttaatcca tgactcatca gatggacatg atatagaatg taagatagat ggttttggag
    78601 ctatgaagct aaagtcttct gttgttaaaa aagcgtaata ttataaataa gctgtagtgt
    78661 ttattgtttt tcagtacagt ataaaaccat aagaatctat taagtaataa aagtttgttt
    78721 atttatcttt atattttctt atggttttat taaatataaa ttttattgaa caccaaaata
    78781 ttctctcctc tacaaataag ccaatcttat ttaaactaat atactttgta ctatttatac
    78841 tgaaattgta aatttaaatg ctatgttatt taggtttgta tagttaattt atatatttct
    78901 gattttataa attgtattta ttattatatc ttgattctaa aatcattaaa aatttcaact
    78961 tctataaaga tttacaattt atcaaataca ttatgagtat ataaacaatt tattattaca
    79021 gtgctacatt taaaataagt cttagtataa aggtattgtt acaagtataa agaaacttat
    79081 gtatgctatt ggaataaata ataccttaaa ttataattaa gaataagaac tgttaaataa
    79141 gggacttgat tatcatttag ttatagataa tataatatta aaaataaagt ttaagaggag
    79201 aaaaaatatg atagatatac ataaaaatat atatgataat aagttatttg aggagctaaa
    79261 gattgactgt aagaagtgct ttggactttg ctgtgtagct ctttattttt ctgcttcaga
    79321 tggatttcct atcgataagg aatcaggaaa accttgtatt aatttacaac cagattttaa
    79381 atgttctgta cataatagtc ttatgaagcg aggttttaaa gggtgtactg catatgattg
    79441 ttttggttca ggtcaaaaag tagcacaagt aacatataag gggatagact ggatgcaatc
    79501 accagaacta acaaatcaaa tgtctgaagt gtttttaatt atgagacaat tacatgaaat
    79561 gttatggtat cttaaagaag catctgtatt aaatatatca gatacaatca aatcaaaaat
    79621 tgatttaata attgaagaaa ctgaaaagat aactaatatg ggcccagaac agataattaa
    79681 tttggatatc atatcacata gaacaaaggt taatttatta ttatcacaag cgagtgagtc
    79741 tgtgatggga aaggttaaat catttatcaa gacttctact cttaaaaaca tgaaaaaatt
    79801 aagtaaaaat atagatttaa taggagcaga ccttagaaaa ataaatctaa taggagcaga
    79861 tttaagaggt agatttctaa tagcagcaaa tttaagaaat acagatttga gtggggcaaa
    79921 tttaatagga gcagacttaa gagattgtga tattagaggt gctaatcttg aaaatagtat
    79981 atttttaaca caattacaag taaatactgc aaaaggagat tctagtacga agttaccagc
    80041 ttcactaata cgccctaaat actgggaaaa ataattaaat taatacataa ttttacaaaa
    80101 tatgaacttt tttgacttta attcatatta tacattagag attctttaca agaatttctt
    80161 aatataatat agggagagat ataaaaatga gttatcaaaa ttataaatgt gaaagagatt
    80221 atgtgtatga tgattataaa tacaataagt gcaacaagtg ctataatgat tatgaggaaa
    80281 tgacacatgt tcatgaatat tcagaaagtg ttaagttagc agaagaatgt gaggatagac
    80341 ataaccaccg tgcagcaggg gttactggtg aagctatacc aataaatgga ggtacaaatc
    80401 atgttcataa aataaatgat aatgtagatt tccttgacca tttccataag atatgtgtta
    80461 caacagggcc agcaattaga atacctggaa ctgataaaca cattcactta atatgtggag
    80521 aaactactgt taatgatggt cattgtcata aattcctttt tactactcaa atagaagcac
    80581 ctttagtata agctgatgtg aattattgta gtgaatttgc tagattatag tataatatat
    80641 aatagataat atttaaactt aatgaggact atgatattta accttcgtag tcctttctaa
    80701 gttttgtata aaaaagtgtt atgcaattaa aagtgatata gggaggaaat ttttatgaaa
    80761 tctggaataa ttcttgaaat gaaacaaata aattcaacag aatatgacga aatgttgcaa
    80821 gtctgggaat catcagtaag agcaacgcat gattttttaa cagaaaaaga tattgaatct
    80881 ttgataccat tagttgagat tggacttaaa gaagtagaaa atatagtttg tataaaagat
    80941 aatgatataa taaagggctt tataggaata gataaagata aaattgagat gctctttata
    81001 gaagataaat atagaggaaa tggtattggt aaaaaattaa taaaatatgc tatagataaa
    81061 tacaatgtaa aatatgttga tgtaaatgag cagaataaaa aagctgtagg attttatatt
    81121 cacttaggat ttaaagtgtt tgataggtct gaaatagatg gacaaggtaa cccatttcca
    81181 atactacata tgaaattaat ttaaagttat acttctcatt tattcgcaaa aatatttact
    81241 taaattttta tacaaataaa agtcgtgaca gtcttaggac acgacttttt tactacacta
    81301 ttaaattgaa atttatctgt tctatattat gattattaga tgtagttttt ttattttaac
    81361 tatgtactta aataccaagt atacccatac ctatcaagta cttcagcagc gccatcattt
    81421 tgatgtggtg gtgggtgtgg taaaaattct tgtacaagtg taccaccttc ggcaagtttt
    81481 acagatattt cttctatcgc ttctcgagat ggtagaacaa cacaaatcgc catgccagaa
    81541 attacaacag gcttgtctgt atccgcaccc attatacaac cttcatattt tgtgaaagta
    81601 acacttgcgt gcataatagg attgtttgga ttgctgtcta atcgcgcaaa tatagttttt
    81661 cctcctccga aagcctcagc ataaaaatta aatgcttttt cacaagtacc attaaatatt
    81721 aaatatggag ttagcatgac caatatatcc tccttgatat agaataattt atagttgcac
    81781 ctgataatct aaattatgat ttagtaaatt gtatcatagg gaaaccttga agtatataat
    81841 tttttattat tatattatac aaatttatta atttaaaaaa atgttatatg tacggaaggt
    81901 ttacaggata aaatataata aaaagattaa ggtgacatta taaaaaatgt atattgacat
    81961 tgacgctacg taattgtata tactttgtct taaaggagat ggtaaatatg aatattatag
    82021 aaattcgctc agataaaata tacaagaaga taatggatgc accaataaac aaaaaagaag
    82081 atatatacag atatgaattg atgaagcctt ttgaatttaa gtggaagtgt atgaatgttc
    82141 caatagttgc tagacagaaa ggtggatatg atgtaattat agcaagtgaa atgttagggg
    82201 ttttatcgcc taaggatatt gatgaaaagc aaaaaaagaa tataaatgtg ttatctgctg
    82261 ataaaatttg gggcacttgc aaagaaacca tagaaaactc tataaatgct tttataaaag
    82321 aagggtatga tttaaacatt aaggactata aatattcaat attattggcg aatccaaata
    82381 gtccttatac aatattaagt gatggatact ggggtgatgg tgggattcct ggatatatat
    82441 ttctatcatt ggttcctaat gaatatacta tcaatagatt accagtatta atagcacatg
    82501 aatgtaatca caatattaga tttcagttta tagagtggaa taataatata acattagaag
    82561 aaatgatgat aaatgaaggt cttgcagaaa attttgcaac atggatgttt ggagaggaaa
    82621 tgttaggacc ttgggtcagt agaacagata tcgaaacatt aaatacttat ataaagccaa
    82681 taataaaaag tgctttaaaa gaaactggat ttcgaaatat aacatcttat ctttatggtg
    82741 atgatatagc taaaatgcaa ggatattttc cagtagggtt gccttattgt gcaggatatg
    82801 cttgtggata ttatatgatt aagtattatt tagaaaagac aaataaatca ataatcgaag
    82861 cgactttatt gccttatagt gagataatcg aagcagtaaa agagttttgg gaataaattt
    82921 tataaattgc ataatttgaa ataaattatg caattatttt atttttaaga aaaaataaat
    82981 tgacaataat ttataagaaa tatacaataa tatatataaa gaaatatttc aatatttaaa
    83041 agttttaaga tttcatatct agagtaccta acattacatg ttagtttctt gttacttatc
    83101 taattacttt atatttcgta gttatatata aaattactat aaaaaatgaa atatattaaa
    83161 caatcaacta aaaaatgaaa tattaataaa a
//
LOCUS       DAMKNB010000009        71455 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.009, whole genome shotgun sequence.
ACCESSION   DAMKNB010000009 DAMKNB010000000
VERSION     DAMKNB010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 71455)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 71455)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..71455
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.009"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            complement(130..324)
                     /locus_tag="PC494_000729"
     CDS             complement(130..324)
                     /locus_tag="PC494_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3911251.1"
                     /translation="MFQVINFLCLFCVGFLVLDVMIYFCKDAMDIFEGTTNVNKVKSI
                     NVWADRVRANSYSYENKIAK"
     gene            complement(633..2162)
                     /gene="lysS"
                     /locus_tag="PC494_000730"
     CDS             complement(633..2162)
                     /gene="lysS"
                     /locus_tag="PC494_000730"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HDF3911252.1"
                     /translation="MKNNQQSNEEAQIQEDLSEVLQVRRDKLKKLQESGRDPFKESRY
                     DRTHYSMDIKDNFDSLEGKTTKIAGRIMSKRIQGKAGFIDIQDQEGRIQSYVRLDAIG
                     EEEYSVFSTYDIGDIVGIEGEIFKTKKGEISVKAKSVVLLCKSLQVLPEKYHGLKDQE
                     LRYRQRYVDLIVNPEVKNAFLIRTKALKALRAYLDDRGFLEVETPILNTIAGGANARP
                     FITNHNTLHIPMYLRIANELYLKRLIVGGFDKVYEMGRMFRNEGMDLKHNPEYTAIEL
                     YQAYADYTDMMEITENVIAHMAEVATGSMIVNYQGTEINFTPPWKRMSMEDCVKEYSG
                     VDFSTINTDEEALEVAREKGIEIKPGMRRGEVINAFFEEFGEDKLIQPTFITHHPVEV
                     SPLSKRNVEDPRRTDRFEAFANKWELANAFSELNDPIDQKGRFIDQLRKRELGDDEAF
                     EMDEDFLKALEVGLPPTGGLGIGIDRVIMLLTNSPSIRDVLLFPTMKPIDNNPNKEEE
                     N"
     gene            complement(2177..2656)
                     /gene="greA"
                     /locus_tag="PC494_000731"
     CDS             complement(2177..2656)
                     /gene="greA"
                     /locus_tag="PC494_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003514606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HDF3911253.1"
                     /translation="MEENKEFLLTQEGYDKLEEELENLKVVKRKEVAERIKVAISFGD
                     LSENAEYDEAKKEQAQVEERILKLENMVRKAVIIDESKIDLNVVTIGSIVKVKDLEFD
                     EEVEYTIVGSTEADPYDGKISNESPVGKALLGRAAKEVVEVQVPDGVAKFEILEIRR"
     gene            complement(2765..3733)
                     /gene="dusB"
                     /locus_tag="PC494_000732"
     CDS             complement(2765..3733)
                     /gene="dusB"
                     /locus_tag="PC494_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HDF3911254.1"
                     /translation="MKIGNLELKNKVFLSPMAGVTDLPFRLICKEQGCGLLYTEMING
                     KALCYDDENTKKMLKIEEEEHPVAVQIFGSEPEFMGRAAEIMNDYSNEILDINMGCPA
                     PKVVKNGDGSALMKNPKLAEEVLRAVVKNSKKPVTLKIRKGWDDNSVNAVEIAKIAED
                     CGISALAIHGRTREQFYTGKADWDIIAEIKKNLSIPVIGNGDVFTIEDSINMLDKTGC
                     DAIMIGRGAQGNPWIFKRINHYMNTGEILPEPTLNEKISTAIKHLKLAVEEHGEYVAV
                     REMRKHIAWYLKGLRNSAKLRDEINKIEDYQEVVSKLEYYMEDSLT"
     gene            complement(3870..4640)
                     /locus_tag="PC494_000733"
     CDS             complement(3870..4640)
                     /locus_tag="PC494_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III pantothenate kinase"
                     /protein_id="HDF3911255.1"
                     /translation="MLLVFDVGNTNMVLGIYKGDKLVNYWRIKTDREKTSDEYGILIS
                     NLFDYDNVNISDIDDVIISSVVPNVMHSLENFCIKYCKKQPLIVGPGIKTGLNIKYDN
                     PKQVGADRIVNAVAGIEKYGAPSILVDFGTATTFCAISEKGEYLGGTIAPGIKISSEA
                     LFQSASKLPRVELAKPGMTICKSTVSAMQSGIIYGYVGLVDKIISMMKKELNCDDVKV
                     IATGGLAKLIASETKSIDYVDGFLTLEGLRIIYEKNQE"
     gene            complement(4659..5249)
                     /locus_tag="PC494_000734"
     CDS             complement(4659..5249)
                     /locus_tag="PC494_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HDF3911256.1"
                     /translation="MMNTSASVRKVNVRKMTIIGVLSAISIMLSMTPLGFIPVGPTKA
                     TIMHIPVIIGAIMEGPIVGAAIGFIFGISSLLNAITNPTVTSFVFINPLVSILPRVMI
                     GVLAYYVYQLIIKATNKVYISGLITGAIGSLLNTAGVLGMIYVLYADKYLHAMGKSGS
                     AGKVIMALAAANGVPEAIVGALVVAAVATVLKKSKK"
     gene            complement(5432..6400)
                     /locus_tag="PC494_000735"
     CDS             complement(5432..6400)
                     /locus_tag="PC494_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P1 family peptidase"
                     /protein_id="HDF3911257.1"
                     /translation="MYNNILDIEGLKVGQVEDRNGLTGCTVVICEEGATCGVDVRGSA
                     PGTRETDLLDPVNMVQKVHAVVLAGGSAYGLESTCGVSRYLEEKGIGFDVGVGKVPIV
                     VGAVLFDLGVGSFKCRPDLKMGYRACEVANTDILNQGNYGAGCGATVGKIRGQEYAMK
                     GGIGSYSIKLDNGLVVSALIAVNALGDVYENGKVIAGALNDKKTETIDTYKLMKQGES
                     KGGFSVDNTTIGIIATNAKLTKAGCKKISQMGHDGYAKSIFPIHTPHDGDTIFTISTG
                     EIEADITLVGSLAVEVVEKSIINAVKKADSVENIMAYKDIVKKREI"
     gene            complement(6393..7370)
                     /locus_tag="PC494_000736"
     CDS             complement(6393..7370)
                     /locus_tag="PC494_000736"
                     /EC_number="6.3.4.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin--[acetyl-CoA-carboxylase] ligase"
                     /protein_id="HDF3911258.1"
                     /translation="MRDKIIEIILNNKSEFISGEELSKQLGVSRAAIWKHMKALKEEG
                     YNIESVNKKGYRLAENPTDLLSPQNIYYKLDTEFIGKNIEHLDTIDSTNEHAKRIAIN
                     SVDGTVILSEHQDMGKGRLGRRWDSKPHEGIWMSIILKPNMEPFKAPFITLIAGASVT
                     KALNNLGANTLIKWPNDVILNGKKICGILTELSAEIERTNYVVLGIGINVKIMDFEQE
                     IADKATSLYKEGYMLSRVDIVRNVLTEFEKLYLDYTVNNSKEKTLKICRDYSAIIDKN
                     IYVLKGDNRELVKCLDINEEGNLLVQRSDGSIKEIISGEVSIRGEKGYV"
     gene            complement(7685..9655)
                     /gene="ftsH"
                     /locus_tag="PC494_000737"
     CDS             complement(7685..9655)
                     /gene="ftsH"
                     /locus_tag="PC494_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HDF3911259.1"
                     /translation="MNKLLKGAGFYLLVFIIIVGIVQFSGKPTEKIKDLKFSEVYREL
                     TDENISRLYFVNQTSVEGTIKDTNTKFKSYVPTEVMGNKLADEVLDQAKAGKLTFGGE
                     AKPSTPWFVEMLPTLLLIFFMVIIWFVFMNQSQGGGGKVMSFGKSKAKVHKDDEKTRV
                     TFKDVAGLDEEKEDLQEVVDFLKNPKKYIELGARIPKGMLMVGPPGTGKTYLSRAVAG
                     EAGVPFFSISGSDFVEMFVGVGASRVRDLFEQAKKSAPAIIFIDEIDAVGRKRGAGLG
                     GGHDEREQTLNQLLVEMDGFGVNQGIIIMAATNRPDILDPALLRPGRFDRQVVVGTPD
                     VKGREAIFKVHSRNKPLSDDVKMDVLARRTPGFTPADIENLMNEAAILTARKREKKIK
                     METIEEAITKVIAGVAKKSKVISEKERRLTAYHEGGHAVCAHVLEEVSPVHQVTIVPR
                     GRAGGFTMQLPVEDKFYATKNEMKENIVVLLGGRVAEELVLKDVSTGASNDLERVTAT
                     ARSMVTKYGMSSKLGPMSFDSDDEVFLGNSFSSKRNYSEEVAFEIDQETKRIVDGAYD
                     KTRSILQENMDRLEYVAQALLIYETLDAEQFVKAFNKELPLNEIENAVTEENSSKEVE
                     EQLTIKLEKDEEERNNVIDINKNLEDKSDKDK"
     gene            complement(9689..11077)
                     /gene="tilS"
                     /locus_tag="PC494_000738"
     CDS             complement(9689..11077)
                     /gene="tilS"
                     /locus_tag="PC494_000738"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HDF3911260.1"
                     /translation="MIFDKVLSTINKHNLIQKGDKIVLGLSGGPDSVCLLHVLNRLKK
                     DFNIEIYAAHLNHQIRGIEAQKDALYVSKLCEDMGIIFFVKSINVPKYCENEGLSLEE
                     GARKLRYEMFYEIKDKIKANKIAIGHNLNDQAETVMMRIMRGTGLKGLKGIDYIRDNC
                     IIRPILDVERNEIEEYCEAYNLNPRIDKTNLENIYTRNKIRLDLLPYMKDNFNSNVIE
                     SIVRMSNSLKSDNDYIEKEAEAKFREVSNIKEKGFVEINLDDFVCLHDAIKVRVLRNS
                     IKHILGDTNFVDQRHIEDIMSLEDNSKVNKMLTLPRNIFVYRKKDSIILTNEEIVNEE
                     IEFYYNVPSNGFIKIKELKQIIETQVMSIDRYKSMKLDNSSKGFDFNKVKGGIVIRSR
                     RQGDKIKLAMGSKKVKDLFIDLKIPREERCKIPIITDSEGIICVGDYKISENYKIDEN
                     TKEVLKINFNKL"
     gene            complement(11260..11688)
                     /locus_tag="PC494_000739"
     CDS             complement(11260..11688)
                     /locus_tag="PC494_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HDF3911261.1"
                     /translation="MEEKSLSVKISINTRQYDEKGNMDTIEMTAFGKIFYKNDGIYVI
                     YKEKEEDIEITNTIKILKNQVSIKKFGAINSTMLFKCGESSTTKYVTPQGTLLIDIDT
                     RELDINIQEGEHIKLKIDYNIKVQDLFLGRNKIDIYIGTK"
     gene            complement(11705..12511)
                     /locus_tag="PC494_000740"
     CDS             complement(11705..12511)
                     /locus_tag="PC494_000740"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HDF3911262.1"
                     /translation="MNNKPIGVFDSGLGGLTVLKEIMKILPNEDIIYFGDTARIPYGS
                     RSKETIIKYTFQAINFLKTKGVKAIVIACNTATARSLKEAQEKYDIPIIGVIEAGART
                     AVSSTKNKIVGIIGTEGTISSKAYNLEISKIDESIEIVNKACPLFVPIVEEGWANTEV
                     AKLTAKIYLQELKEKNIDSLVLGCTHYPILKRTIGEEVGEHIKLVNPAKETAKDLKKI
                     LEVQNIINNTEIHGTYQYYVSDIPEKFSDIAREFLKKKIDKIQKVEIQKY"
     gene            complement(12713..13198)
                     /locus_tag="PC494_000741"
     CDS             complement(12713..13198)
                     /locus_tag="PC494_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall hydrolase"
                     /protein_id="HDF3911263.1"
                     /translation="MATLLALTFIFMPIKEVFAYEPTENIKKVNKQEKNIAKKEVINL
                     SDNDLMLLSKLVAGEARGESYEGQVAVAAVVINRVLDPRFPDTIEEVIYQKNAFSVVL
                     DGSIKMAPTDSARKAAQEALYGTDPTNKAVYFWNPEIATCKWINRLNPYMRIGNHVFA
                     K"
     gene            complement(13249..13908)
                     /gene="spoIIR"
                     /locus_tag="PC494_000742"
     CDS             complement(13249..13908)
                     /gene="spoIIR"
                     /locus_tag="PC494_000742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage II sporulation protein R"
                     /protein_id="HDF3911264.1"
                     /translation="MRKIKIRLGLLILSLISVISIMTIVINGEVKKVDNISKDYKDKL
                     IRFHVIANSNTDEDQELKLKVRDEVIKYLQPKLQNSKSIKESEAIIKKEYSSLEEISK
                     NIILKNGYNYSVKVGIQYSNFPTKQYSNIVLPAGEYKALKIIIGKGEGKNWWCVMFPP
                     LCFVDESNGVIDKSTDDKLKEVLTDKEYKLIKQDTPKKTSRVKIKFKVLEVVKDLEKK
                     F"
     gene            complement(14053..14733)
                     /locus_tag="PC494_000743"
     CDS             complement(14053..14733)
                     /locus_tag="PC494_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDF3911265.1"
                     /translation="MENLTKLNLDNYKPLRDVVFENLREAILEGKLKPGQRLMEVQLA
                     EQLGVSRTPVREAIRKLELEGLVVMLPRKGAYVANMSLKDIMDVLEVRASLEGLAAYL
                     AAERISDEDIKKLKDISEEFKKSTLESDVDALLKLDVEFHECIFKATNNKKLIQLINS
                     LWEQVYRFRVTYMSAYDTSHNIVEEHKYLLDAIIKGDSELSKKYATEHIEKAEQFMID
                     KAMISKDL"
     gene            complement(14717..15607)
                     /locus_tag="PC494_000744"
     CDS             complement(14717..15607)
                     /locus_tag="PC494_000744"
                     /EC_number="2.7.1.148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-(cytidine
                     5'-diphospho)-2-C-methyl-D-erythritol kinase"
                     /protein_id="HDF3911266.1"
                     /translation="MDFIRLKSRAKINLSIDVLGKRQDGYHFVEMIMQTIDLYDIVKI
                     KELDEDEIKVKSTSLDIPLDEDNIVYKAAKILKNKFYIKKGVEIFIEKNIPVAAGMAG
                     GSSNAAAVLVGLNHLWELRLSEDELKEIGLNLGADVPFCISGRPALAQGIGEKLTKIK
                     GLPCDTNILICKPDLFVSTKEVYQGLDLNNIKKRPNNKYLIECLKSEDIKAVSESMVN
                     ILENVTIGKHKEISDIKQVMMKNNALGSMMSGSGPTVFGLFKNKEDALIGKKELLKKY
                     KQVYVVNSSQKGVEICGEFN"
     gene            complement(15725..17275)
                     /locus_tag="PC494_000745"
     CDS             complement(15725..17275)
                     /locus_tag="PC494_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3794 domain-containing protein"
                     /protein_id="HDF3911267.1"
                     /translation="MELIKDVIKVDNRIDFGKFQTFIEAEAVVPDKKLDVYEIVKTEG
                     YISLKKIEMADGKILCRGSFNYNVIYIADDKNTISNVDGKVDINEVIEKDNVVQDMEY
                     MLFSEVEHMDCTIMNERKIKVGALMNIRGSLFEKQRLDIVKDVAQVEGIQKHRKEICF
                     QDIVGIEKAESSIRDTITINTEEIQSIISLNPCVKVKESRVTDNKVIIGGVLEINPLA
                     CTYEGELVELDRVGIEFTQFVEVPGVSDGMTEEVLLSMSDFNHIFKQNSESNTGLLEI
                     DCMACCKVKVTDEVTREVLQDAYSPQKIIKFDHKPIQLNKTLRRSEETFMVREGIRND
                     NDDIQIKDIVSVCPTMSIENSYIEGNKSIIQGIIKVEILFVPVEGLKLVYKISEEIPF
                     EHDIEMDNLTDTASVFNTACIDKVEVDLNRDQIDLIIKIKRFTEALDKKAENFIIKGE
                     DQGVYDLSKAPSIIVYICKEGDTFWNIAKKYNTTENEIAELNDIKLDEPIKPGKCLIL
                     EKKVVLVD"
     gene            complement(17369..17635)
                     /locus_tag="PC494_000746"
     CDS             complement(17369..17635)
                     /locus_tag="PC494_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Veg family protein"
                     /protein_id="HDF3911268.1"
                     /translation="MATVQTLDKIRVSLERHIGKKILLKANKGRKQIITKEGILEKVY
                     PSVFVIKLDDESNGYPRVSYSYSDLLTSNVKLQVFRDQDKLQIS"
     gene            complement(17783..18643)
                     /gene="yabG"
                     /locus_tag="PC494_000747"
     CDS             complement(17783..18643)
                     /gene="yabG"
                     /locus_tag="PC494_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation peptidase YabG"
                     /protein_id="HDF3911269.1"
                     /translation="MKVGDIVARKSHNKDIVFKIVSFGVDENNEKIAILKGIAFRVIA
                     DAYIDDLELVKAPDIKDILIDKNVENLLYKSVRKAKERQKRMTRAVPKLQLNPNTYGM
                     PGKVLQIDGDKEYLKICLDVYAQLGIPAVGVAVSEQNQYKEVRALLEKYNPDILVITG
                     HDAMTIKRGDIEDMSNYRNSSNFVKTVKEARKWQPNLDNLVIFAGACQSNYEKIISAG
                     ANYASSPGRIMIHALDPVFIVEKIACSRIDVVVPIDEVIEQTITGVKGIGGSETRGKF
                     RWAMPKTILH"
     gene            complement(18727..19665)
                     /locus_tag="PC494_000748"
     CDS             complement(18727..19665)
                     /locus_tag="PC494_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase"
                     /protein_id="HDF3911270.1"
                     /translation="MKFIDLHCDTIAKLMENVETSELKSNKYSVDIDRLKKGDSLAQT
                     FALFVDTEEVKHPFDYCMSMANKFHEEMKKNSDEIALATNYEEIMKNQSEGKLTALLS
                     IEEGAVLEGKLENLKKFYDLGVRMMTISWNHVNELSFPHNKVEYREKGLTDFGREVVH
                     KMNELGMLVDVSHISDGGFYEIAKISSKPIIATHSNSRAMMNHSRNLTDDMIKVLANK
                     GGVTGINFFHLFLSDKSESKLEDMVRHIKHIVNVGGIDVVSLGSDFDGIDSKVEIEDI
                     SQMGKLYEPLKKEGFSEDDIEKIYYKNALRVIKEVL"
     gene            complement(19775..19936)
                     /locus_tag="PC494_000749"
     CDS             complement(19775..19936)
                     /locus_tag="PC494_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3911271.1"
                     /translation="MFILRFADDDDNLSVKDFTSLTDLKKYISENNIDKTWHQIEEVK
                     KVIPNLKEE"
     gene            complement(19946..20443)
                     /locus_tag="PC494_000750"
     CDS             complement(19946..20443)
                     /locus_tag="PC494_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SEC-C domain-containing protein"
                     /protein_id="HDF3911272.1"
                     /translation="MSLYTEWRNLSDNHESQEAEVKFWEEYLKVEAGIYNEILNNKMD
                     VVEGKVSELAEKFGTTNEFFMGFIDGISESLKEDIVLEEVEADKEVSIKIDWEKLYNN
                     MVTVEAHWLYNLQGWEDILPADQRKEIIKAYKKSKTIVKEAKIGRNDSCPCGSGKKYK
                     KCCGK"
     gene            complement(20558..21268)
                     /locus_tag="PC494_000751"
     CDS             complement(20558..21268)
                     /locus_tag="PC494_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0489 family protein"
                     /protein_id="HDF3911273.1"
                     /translation="MENYEYSGFYIEKPVGNNVFSYDKRENKSIYVPKLINGTLNDVR
                     LGNEVVFNEVDENKEIKAKGLENMVEYVLGNKKIYVFDNHNHAFYFWAKSLLKGEFTK
                     GCKLVHVDQHKDTREPENYDVDVNNLKDVFRYTNEVLNVGSFIKPALKYNIFSELIII
                     DSLYGFDLEVESEFVLDIDLDIFSSDMDYIPFELKFYKIKNLIKKAKVITIATSPYFI
                     NQEYAIKVLKELFNYDII"
     gene            complement(21444..21974)
                     /locus_tag="PC494_000752"
     CDS             complement(21444..21974)
                     /locus_tag="PC494_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3911274.1"
                     /translation="MDIRALPIRITKEEAIEIAKSGKNSLFSKLILKNKYAHEVRLHY
                     IEFKIITLKIHKTKSIFKNRRYSNYINELKILVNGSTGSGSIVQDFPTYEVVKNVDCN
                     IVQYSDKDERRVKAKANKMAMRLTHRFMGGIPEIEIVKIESIFRPYWVVFFGKVELNR
                     RVSYLPIEADGFVIGM"
     gene            complement(21991..22221)
                     /locus_tag="PC494_000753"
     CDS             complement(21991..22221)
                     /locus_tag="PC494_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3911275.1"
                     /translation="MSKLVSKVKKDLEIKWLGIDGFLVLLYFLITGFIFYGILTRNDI
                     IVGKIIPYGVMSVVIVIFFDYIYRVLKMTRKK"
     gene            complement(22236..23630)
                     /locus_tag="PC494_000754"
     CDS             complement(22236..23630)
                     /locus_tag="PC494_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:solute symporter family protein"
                     /protein_id="HDF3911276.1"
                     /translation="MLTFWENGIIVIFAFILLGIGYYFSRNVKDMESYYLGNRSLPWS
                     LIVGTLVASWYGGVGTVGSVEYAAIYGISAWAVWSIAAHIGRMPLALWVGPRIHIRTN
                     ITVPDLLESFYGKHVAIIGAILMFIYCAQLGEITAMGTIGNVAWKIDKELIGLIMVGV
                     VVVLTVLGGLMGVAITDMVLFFCMVFGLTMVMPGQFEQIGGFQGLTEALKDAPQLMHP
                     TKGMSAMKALMLIVYSFGAYSDPTFYQRFSAADSPKVGRRALLTCFSLWICFDMVLTM
                     TGLIVRATYPEMAPAAGYITLVLDTLPQGIRVIFIIGILGSIISTLDSYYLAAGATLA
                     NDIYGRITKKELSQKQLVKFTRIGVCLAAVMGLSVAFRFENVYDACIFVGSIWMGSAF
                     VPIVGGLLGNGRRTSMGGILGMIVGGVTFGYFKIFPVQSFELEPLVIAIPFSFIAWMI
                     GNRIGENLNTQNNL"
     gene            complement(23756..25009)
                     /locus_tag="PC494_000755"
     CDS             complement(23756..25009)
                     /locus_tag="PC494_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDF3911277.1"
                     /translation="MESKNNVKRFLIIFILAFGTTAMYSLPYMKSSFYDPMQQALALS
                     HTQIGNLLSLYGLVGMVSYFIGGWFADRFSVRKLITFSLIASGILGFYFSTFPSYSMI
                     LLIFVLWGFTTILTFFSASVKVVRMQGSESEQGRIFGFYEGLSGVSGTLISFIGLYFF
                     GKFAEITVGFKYVVWLYSAASIICGILLFFLVEEKKDSGASDEGLSIKSLLKVVTMPK
                     AWLIGLIIFSTYLVFSSLTYLSPYLSEVYVMPMTLVSALSIIRTYVIKMGASPVAGVI
                     TDKVGSSIRVMFVGFILMTVSTAAYLVIPKSTGFIWIAVINMIILSVILFGFRGIYFA
                     SVSESNISLETTGAVVGFASFIGFSPDAFYYTIAGNWLDKYGQTGYTYIFILSVVCAV
                     IGIFATYALNKINKRENKGLNNKIA"
     gene            complement(25060..26214)
                     /locus_tag="PC494_000756"
     CDS             complement(25060..26214)
                     /locus_tag="PC494_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HDF3911278.1"
                     /translation="MSNNINQDLETKIIHWGHSADPTTGALATPICQTATFAAKTVEH
                     FEELCMTWGYVYTRECNPTLTELEAKLAMLENAESAISSTSGMGAITSTILALVKSGD
                     HIVSSDGIFSHTKLFMSELLSKFGVEVTFVDAVNPQNVKEAMRPNTKIVYIESPLNPS
                     LDLVDIKTIAEIAHENKSLAIVDSTFGTPIVQRPIDLGADLVIHSLTKFINGHGDTLG
                     GAVAGSKELIDLVRWPSLCCFTGASLPPMSAWMILRGMKTLDMRMKKHCENGLAVAEF
                     LEEEENVELVKYPALKSHPQYELCKTQMNGLGGGVVSFKLKDGINGLTRDQASRRLMN
                     SLELATIATSLGEEHTLVQMNGENLIRIAVGLESSNDIINDFKQAIEKLK"
     gene            complement(26774..27343)
                     /locus_tag="PC494_000757"
     CDS             complement(26774..27343)
                     /locus_tag="PC494_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HDF3911279.1"
                     /translation="MIIIYGYCRVSTKNQTDNNSLYQQQQEILNKYNDAKIIKETYTG
                     TTTNRPKFEKIISSLKKGDLLVATKLDRLARSTSEGIQLIEGLFAKEVSVHILNIGLL
                     ENTSMGKFFLTTLLAVAELERNMIIERTQLGKEFAKKKKDFKDGRPKKYSNQQIQYAL
                     GLLNSKPYREVVKMTGISKSTLIRAKKSI"
     gene            27546..27773
                     /locus_tag="PC494_000758"
     CDS             27546..27773
                     /locus_tag="PC494_000758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HDF3911280.1"
                     /translation="MNSLLKEAIDELKNIHCGEVFLLKELFKGYEWNRLEMNIRLKLG
                     KLFLYEVVTNPNLNVEVINKNSAYQQMYKKK"
     gene            complement(27992..28735)
                     /locus_tag="PC494_000759"
     CDS             complement(27992..28735)
                     /locus_tag="PC494_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3298 domain-containing protein"
                     /protein_id="HDF3911281.1"
                     /translation="MENYQSTNTCTYNILYVQFNEDFERSKYFSYDVKYPVIYNIRNQ
                     STYVNPVILNNINNAVRMTVNNFKNGLQEEEREYNNATSQNSLPKQSYWVSTSYAVTF
                     NKNYVLSMILNLMGFANNYGPKYNTLNNYNIDLTTGKELLLNDIFRDGVDYINIITDY
                     IKSQINENREMYYSNVELVIPEDQAFYLTDNGIIIYFGVDEIAPESFGIPKFELKFSD
                     FGNFINLRFYCISPDIYVQSRGRAKHFMG"
     gene            28903..29775
                     /locus_tag="PC494_000760"
     CDS             28903..29775
                     /locus_tag="PC494_000760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HDF3911282.1"
                     /translation="MLLLADKWKDYELIDMGNGEKLERWGSYVLRRPDPQVVWPMESE
                     WALWKNPHGHYHRSNKGGGQWEHKKRYPEQWTINYKNLKFHIKPTGFKHTGLFPEQAA
                     NWDWMIEKIKKANRPIKVLNLFAYTGGATVACASAGAEVCHVDAAKGMVNWAKENIEL
                     SGLKNQTVRFIVDDVVKFVEREIRRGKKYDAIIMDPPSYGRGPKGEVWQIEEKLYSFV
                     DLCMGVLSDNPLFFLINSYTTGFSPIVLENVLSTTIGKKTNTGDIYGGELGIPASRDG
                     KILPCGIFGRWEKK"
     gene            29775..30440
                     /locus_tag="PC494_000761"
     CDS             29775..30440
                     /locus_tag="PC494_000761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HDF3911283.1"
                     /translation="MIKVIYEDNHLLVVEKPVNILSQGDNTNDKDMVNLLKDYIKKKY
                     NKPGNVYIGLIHRLDRPVGGVMVFAKTSKAASRLSEQVRSKTFKKTYLAVVHGKIKSN
                     SDILKDFLYKNKKTNMVTVVKKSHKDAKEAELNYNVLDFKENLSLVQVNLKTGRSHQI
                     RVQFASRKHPLYGDQRYGKEINKIGQQISLWSNKIEICHPTTKEKMEFTCHPPDKYPW
                     NIF"
     gene            30461..31318
                     /locus_tag="PC494_000762"
     CDS             30461..31318
                     /locus_tag="PC494_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HDF3911284.1"
                     /translation="MSKKFSIGEMSKLHKISIQTLRYYDQIDLFKPVHVDQESNYRYY
                     SIDQFSQLDIIKYLKYLGMPLKEIKSKLDENNEEILKLLTNKINIVDEKIKELELIKK
                     VLSTKKETMEKGMKVDEVGKIVRKHIPRRSILSIEYEEGLSSEETMELSRRQIANILE
                     DNISVFYGGVSGLVSIDKFLKEDKVIYDNSFVTVERDLFDIKSQKHITEISSGDFICM
                     TYKGPYKENYTAFKKLVDYVEYKRIPIENYIYEIPIIDPLSTNNEEELLTEIQIQVKK
                     REIDLRCLV"
     gene            complement(31474..34020)
                     /locus_tag="PC494_000763"
     CDS             complement(31474..34020)
                     /locus_tag="PC494_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HDF3911285.1"
                     /translation="MNIFNKVALQGLKKNRTRTLVTIIGVVLSAAMITAVTTFGVSLM
                     NYMTNGAIIKYGDWHVQFLDVDSSFVQEQRVNDEVANTATFENIGYATLEGNRNPDKP
                     YLFIAGFSKEAFDTLPITLISGRLPENSREILVSSKVATDGGVKFAVGDTISLDVGKR
                     MSENEKLGQSDPYTAGSEVFVPQDKKTYTVVGICRKPVFEESSAPGYTLITKEDKQVK
                     TDSLSLFVTLKNPHQIRSYISSTKDHASIFNDNVLRFIGVSDNNLFNMFLYSVGGIVL
                     AIIMLGSIFLIYNSFNMSLNERTHQFGILSSVGATAKQLRNSVLFEGICIGAIGIPIG
                     VAIGIVSIGLVISVIAKNFANILYVNVPLTLTLSIPAIIVAAVVSMVTILISAYIPAR
                     KAANTPVMECIRQTNEVKIESKSVKTSKLTQRVYGLEGVLAMKNFKRNKKRYRSIVLS
                     LVLSIVLFISTSALVADLKQMSNQRSEVTDQDIIFSTQGMKDNEMLKLYDKLKTANGV
                     YEGLYQKLMTYSCVAKVSELTDDYLNYEGSHSMSEMLELPVDMQFLDDRTYLNIIKSL
                     GLPAEEYTGQNAKLIAVSMVTKDNNIIDIFNSSSMNVSLTPETNGKLEIPERQNVNIS
                     FVKVVPPDSPPGIRSSDVKKASFRVLAPYSAKDKFEIPGVSTGIESLSFQSKNPTQSV
                     AEMEQIIESEGVTNEYNLYNMYGMMDENRNYIFIANVFAYTFIIMISLISIANVFNTI
                     STNIKLRRRELAMLRSVGMSEHDFQKMMNFECAFYGMRALFFGLPIAVISSWLIHKVM
                     VTDDIDFVIPWFSIGISIFSVLFIVFITMLYTINKIKKENIIDALRDDMA"
     gene            complement(34020..34706)
                     /locus_tag="PC494_000764"
     CDS             complement(34020..34706)
                     /locus_tag="PC494_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF3911286.1"
                     /translation="MAFLKIEDLCKVYGKNENKVTALDHVSLTIEKGEFTAIIGSSGS
                     GKSTLLHSIAGVDVPTSGKIYLEGQDVYGQSNEKLAIFRRRQVGLIYQFHNLIPTLNV
                     VENITLPILMDKRKVNQERLNDLLELLGLKERKTHLPNQLSGGQQQRVAIGRALMNAP
                     AVMLADEPTGSLDSKNGQEIIQLLKESHSKYHQTLIIVTHDENIALQADRIICISDGK
                     VVRDERKVNR"
     gene            complement(34789..35778)
                     /locus_tag="PC494_000765"
     CDS             complement(34789..35778)
                     /locus_tag="PC494_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF3911287.1"
                     /translation="MFRNREFRKFAILFLLITILTVALGFAISIMTGILSIVSATTFG
                     IAFFVFTKNRYKSIAQISEQINLVLHNANHLYIAESDEGELSILQSEITKMTLRIREQ
                     NYALKKEKEHLADSLADIAHQLRTPLTSVTLILSLLENTSDEDERKELIRETEELLIR
                     MDWLITSLLKLSRLDAGIVVFQKEQIDVNNLISSALHQLLIPMELHNITLHIDIPKGV
                     RILGDLNWLSEAIQNIFKNCMESVGDNGKIDIICEDNFLFTQLTIHDNGAGFKKEDLP
                     CLFNRFYRGKNSSTAGYGIGLALCKTIIMRQGGTITAQNHPQGGAIFVIRFPK"
     gene            complement(35765..36451)
                     /locus_tag="PC494_000766"
     CDS             complement(35765..36451)
                     /locus_tag="PC494_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF3911288.1"
                     /translation="MKRIFLVEDDKAIAKNLILLLNSEGFIVTHVSTRSEALVEIAKN
                     KFDLALIDISLPDGNGFTICTEIKEKQDIPVIFLTASGDESSVVTGLNMGADDYITKP
                     FRPRELIARIRTALRKSGRFGSTFEICGLYVDTATGVVKKNGNEVFLSALEYRLLLVF
                     ISNPKSIITRVRLLDELWDAAGEFVNDNTLTVYIKRLREKIEDDPSSPQIILTVRGTG
                     YRLGGSYVSK"
     gene            complement(36951..40157)
                     /gene="carB"
                     /locus_tag="PC494_000767"
     CDS             complement(36951..40157)
                     /gene="carB"
                     /locus_tag="PC494_000767"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HDF3911289.1"
                     /translation="MPKLDSIKKTLVLGSGPIIIGQAAEFDYSGTQACQALKEEGIEV
                     VLVNSNPATIMTDKEIADKIYIEPLTIEFIEKIIEKEKPDSLLAGMGGQTGLNLAVEL
                     HDAGILDKYNVKVIGTSIESIKKGEDRDLFREVMKEINQPVIVSDIVTNLEAGLEFAN
                     KIGYPVVVRPAYTLGGTGGGIADTEEELREILSHGLQLSPVGQVLLEKSIKGWKEIEY
                     EVMRDGNGNCITVCNMENVDPVGVHTGDSIVVAPSQTLSDEEYQLLRKASIDIINAIE
                     VQGGCNVQIALNPHSLEYAIIEINPRVSRSSALASKATGYPIAKVAAKIALGYTLDEI
                     ENAVTKKTYACFEPTLDYVVVKIPKWPFDKFRHANRKLGTKMMATGEIMSIGSNFEAA
                     ILKGIRSLETGKYSLVHAPSEGRTLEELKARVVVPDDERLFDLAEMIRRGYKVEMISE
                     ITGVDKWFINKFKWIVEQEEKLKVLKIEDLDKEYLHELKKKGFSDKGISDLMKISPEK
                     LYELRSLYNIQPVYKMVDTCGGEFEALSPYYYSTYEQYDEVVVSDKRKVVVLGSGPIR
                     IGQGIEFDYCSVHCVKSLRKMGIETIIVNNNPETVSTDFDTSDKLYFEPLTEEEVLNI
                     IEKEKPEGVILQFGGQTAIKLAKFLHEKNIPILGTDFRDIDAAEDREKFDDLLERLDI
                     NRPKGKGVWTTNEGVEIAKELGYPVLVRPSYVLGGQGMEITYNEEKLIQYLDDAFDRD
                     HKNPVLIDKYLTGREIEVDAICDKEDILIPGIMEHLERAGVHSGDSTTMYPSQNISDE
                     IKEKIVEYTKKIALDLNVLGMVNIQFIEFQNELYIIEVNPRASRTVPYISKVSGVPIV
                     DLATKCMLGAKLKDLGYSTGVYKEPKLVSVKVPVFSMSKLSKVEVSLGPEMKSTGEVL
                     GVGENLEEALYKGFLAAGRHMSDERGVVLATVNNHDKDEFIEIAKDMKELGYTFVATE
                     GTAKSLRENGIEADIVNRIEEPRPNILDAIRNKQVDIVINTPTKGNDSTRDGFKMRRT
                     AIEFSTEIMTSLDTLKALVEVKKKHLNKDKLKVYNIAE"
     gene            complement(40350..41399)
                     /gene="carA"
                     /locus_tag="PC494_000768"
     CDS             complement(40350..41399)
                     /gene="carA"
                     /locus_tag="PC494_000768"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002845470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HDF3911290.1"
                     /translation="MKARLILEDGTVFIGKAFGYLEESVGEVVFNTSMIGYGEVLTDP
                     SYYGQIVTMTYPLVGNYGINLSSAESEKVQVKGFIVREKSDSPSNFRCEIDIDQYLKQ
                     NKVIGLEGIDTRALTKILRNNGTMKGIITLEDSKLEDVKHKLDKFSNTEAVRTVTRKE
                     VEHIKGNGPKVAVMDFGVKRNILRSFIARGCDITIFPATTSPEDVLSINPDLIFLSNG
                     PGDPEDLEDVIENIKALIGKKPIVGICLGHQLLALALGGKTAKLKFGHRGGNHPVKDL
                     EEGKVFITSQNHGYYVSEVPEQMKVTHINLNDNTVEGMRHEKLDVYSVQYHPEACPGP
                     KDNDYIFDKFLELVK"
     gene            complement(41656..44862)
                     /gene="carB"
                     /locus_tag="PC494_000769"
     CDS             complement(41656..44862)
                     /gene="carB"
                     /locus_tag="PC494_000769"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HDF3911291.1"
                     /translation="MPKLDSIKKTLVLGSGPIIIGQAAEFDYSGTQACQSLKEEGIEV
                     VLINSNPATIMTDKEVADKIYIEPLTIEFIEKIIEKERPDSLLAGMGGQTGLNLAVEL
                     YEKGILDKYGVKIIGTSVESIKKGEDRDIFREVMKEINQPVIVSDIVTDLQAGLDYAL
                     TIGYPVVVRPAYTLGGTGGGIADNEEELREILSHGLQLSPVGQVLIEKSIKGWKEIEY
                     EVIRDSKGNCIVVCNMENIDPVGVHTGDSIVVAPTQTLSNKECAMLKKASLDILNAVE
                     VQGGCNVQFALNPHSFEYAVIEINPRVSRSSALASKATGYPIAKVSSKIALGYTLDEI
                     ENAVTKKTYACFEPTIDYVVAKIPKWPFDKFKKANRKLGTKMMATGEIMSIGSNFEAA
                     ILKGIRSLETGKYSLVHTPSEERSIEELKKRVVVPDDERLFDLAEMIRRGYKVEMIEQ
                     ITGIDKWFINKFKWIVEQEEKLKVMKIEDLTKDYLLELKKKGFSDKGISDLMKISPEK
                     LYELRSLYNIKPAYKMVDTCAGEIDAISPYYYSTYEQYDEVVVSDKKKVIVLGSGPIR
                     IGQGIEFDYCSVHCVKSLRKMDIETIIINNNPETVSTDFDTSDKLYFEPLTEEEVLSI
                     IEKEKPEGVILQFGGQTAIKLAKFLHEKNIPILGTDFDDIDAAEDREKFDDLLERLDI
                     NRPKGKGVWSLNEGIEVANELGYPVLVRPSYVLGGQGMEITYNEEKLSQYLQDAFDRD
                     HKNPVLIDKYLTGREIEVDAICDKEDILIPGIMEHLERAGVHSGDSTTMYPSQNISDE
                     IKEKIVEYTKKIALDLNVLGMVNIQFIEFQNELYIIEVNPRASRTVPYISKVSGVPIV
                     DLATKCMLGAKLKDLGYGTGVYKEPKLVSVKVPVFSMSKLSKVEVSLGPEMKSTGEVL
                     GVGENLEEALYKGFLAAGRHMSDERGVVLATVNNHDKDEFIEIAKDMKELGYTFVATE
                     GTANSLRENGIEADIVNRVEESRPNILDAIRNKQVDIVINTPTKGNDSTRDGFKIRRT
                     AIEFSTEIMTSLDTLKALVEVKKKHLNKDELKVYNIAE"
     gene            complement(44915..45958)
                     /gene="carA"
                     /locus_tag="PC494_000770"
     CDS             complement(44915..45958)
                     /gene="carA"
                     /locus_tag="PC494_000770"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HDF3911292.1"
                     /translation="MKGKLILEDGTVFEGKAFGYLKEAIGEVVFNTSMAGYGELLTDA
                     TYYGQIVTMTYPLIGNYGINLEDVESNKVQVKGLIVREKSDNPNNFRCEMDIDTYLKQ
                     NKVIGLEGIDTRALTKIIRNNGTKRGIITLENVSLQDVQSKLEEHCNKDSVKNVTRKE
                     IENIKGTGAKVVVIDFGVKNSVLESLKACNCDITIVPAMTTVEEILNINPDLILLSNG
                     PGNPEDINDIVENIKKLIGKKPLTGIGLGHQILALALGGKTSKLVFGHRGGNHPVKCL
                     ETGKVFITSQNHGYNVSEMPENTEVTHINLNDNTIEGMRHKELPIYSVQYIPEYTTKE
                     DLDCIFNKFLALI"
     gene            complement(45984..46700)
                     /gene="pyrF"
                     /locus_tag="PC494_000771"
     CDS             complement(45984..46700)
                     /gene="pyrF"
                     /locus_tag="PC494_000771"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HDF3911293.1"
                     /translation="MINGKEKLIVAIDTDEFDKAKELIDRLEDSVDIFKVGLEQYVAT
                     KGKTIDYLKEKGKKIFLDLKFHDIPNTMKSAVKAAVRDNVWLMTIHVSDMEGMRQCAL
                     IAREEAERLNIEKPLVVGVTVLTSLSNQDLQDIGCNMTTEELAIKRAKLAKESGIDGV
                     VCSAQEVDKIVEACGTDFITVCPGIRPKSAEVGDQKRVVTPSDAIKKGAHYLVVGRPI
                     TKAENPRESAINIVREIENA"
     gene            complement(47076..47711)
                     /locus_tag="PC494_000772"
     CDS             complement(47076..47711)
                     /locus_tag="PC494_000772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1847 domain-containing protein"
                     /protein_id="HDF3911294.1"
                     /translation="MYKCGKCNLRGCSNGNMDKLMKICPTREIELQQKAKQLYEEEEN
                     RKIAYNAGLVEAEGYCQYTRLKEIIEFAKKCGYKKIGIAFCIGLKREMQTVQKIFEHH
                     GFEVFSVICKNGAMPKSTIGLEASQTISKCSDEVMCNPIGQALFLNEAKVDLNVILGL
                     CVGHDTLAMKYMEAPITTLVVKDRVTGHNPVAAIYNAESYFEKKLFDKDEE"
     gene            complement(47735..48649)
                     /locus_tag="PC494_000773"
     CDS             complement(47735..48649)
                     /locus_tag="PC494_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3911295.1"
                     /translation="MELYEAIFYRKSVRNFSSKKIKKPLMEEIKRSCKNLEYLNEDLN
                     IKAHVVDRGHIIHFLMGKECKVKAPHYIVVTSDKGEDYLQNIGFATEGVVLRLTTLGI
                     ATCWLEGNLKREDILEFVDIGNKNFEEDEEDDLDYLAGIKTEEDDENKIENPYIIIAF
                     GYPAKNEELFRTRYARPDRKPVKDMINKINRNRKWKDILELTRRAPSVKNSQPWYFHK
                     DERGLHLFEKRPKKHCEDMNKVSLGVALRHFDIACIKNKIDVSYEKLPIRNKIGKSYF
                     ITVVEHVKPEEETQEENVTLEKEESQDE"
     gene            49250..50479
                     /locus_tag="PC494_000774"
     CDS             49250..50479
                     /locus_tag="PC494_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HDF3911296.1"
                     /translation="MNLNRNLEKYAELAIKVGVNIQPGQILLIKSPIECADFARNALK
                     EAYKCGAKNVYIEWSDEESTLIKYLYAPDEAFHEFPKWTAEQYVDIAKEGGAFLSVYA
                     QNPDLLKDVDPERVANFQKASGKALKEWRSYTLTDKCKWSIVSVPTKDWAKKVFPNLS
                     EDKAIEKLWDAIFKCSRVDGQDPIKAWEEHNENLKSKMDFLNKNNFKTLKYKSSKTDL
                     TLDLPKGHVWLSGASKDPNGISFNPNIPTEEIFGMPHKFKVNGTVYSTKPLVYGGNII
                     DNFFLTFKDGKIIDFSAEKGLDTLEKLIETDEGSHYLGEVALVPYNSPISNTDIIFYN
                     TLYDENASCHFAIGSAYKTCLEGGNNLKDEELDEHGVNDSLTHVDFMIGSADMDIIGE
                     TYDGKQIQIFKNGNWAF"
     gene            complement(50684..53065)
                     /locus_tag="PC494_000775"
     CDS             complement(50684..53065)
                     /locus_tag="PC494_000775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homocysteine S-methyltransferase family protein"
                     /protein_id="HDF3911297.1"
                     /translation="MEIRQYLKNNILIFDGAMGTMLQQKGLKLGENPEVFGLQNPDKL
                     IEIHTAYLEAGSNVILTNTFGCNELKLDSKYTVEEVIDNAVLVARKAIENVDNTKPRY
                     VALDIGPIGEMLEPMGTLSFDKAYEIFKRQVLQGVKSGVDVIVIETMMDLYEAKVAVL
                     AAKENSDLPIFCTMTFDEGGRSFTGCMPECMVATIEGLGVDAIGVNCSLGPKQLLPIV
                     EKIASRATVPVMVQANAGLPNIVDGEAIYDVDAKEFFEGVKKFVEVGATIIGGCCGTN
                     PSFIKEISENINSVTKGCIEKIDKCVVCSPSKFVEVQSPTVVGERLNPTGRKSLQEAL
                     KNENVDYAINLGLEQVNAGAQILGVNVGLPEIDEKKLMPKLIREIQAVVDTPLQVDSS
                     NVEALEQGLRYYNGRTIVNSVNGKEESLESILPIVKKYGSCVVGLTLDEKGIPKKAEE
                     RFEIAKRIVNRAVSYGIKPKDIFIDCLSLTVSAQQEEAIETIKAITMVKTLGVKTILG
                     VSNISFGLPNRKALNASFLTLALGAGLDLAIINPNEYSMMEAINSFKILNNTDKGCIN
                     YINQYSNINNSKKSDSSTKIDKDLPLDILVERGLKDEAKNVTLNLLKEKDENYILDEI
                     LIPALDKVGKRYDSGDIFLPQLIQSAETVKVSLNTIKETLLSKSSNNVSKGKIIVATV
                     KGDIHDIGKNIVKIMLENYGYEVIDLGKDVPIEEVVEVAKKRNIKLVGLSALMTTTVQ
                     SMKDTIQALRDNEINAKVFVGGAVLTEEYAEEMGADYYSKDAKSAVEIAKLNF"
     gene            complement(53037..53762)
                     /locus_tag="PC494_000776"
     CDS             complement(53037..53762)
                     /locus_tag="PC494_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Vitamin B12 dependent methionine synthase,
                     activation domain protein"
                     /protein_id="HDF3911298.1"
                     /translation="MENNLIGREDISINQSEVLRYLQYRGQEIDKDLKYTIDECVAIT
                     KNKINPRYLSRIYPIKINKDNVVELEGTNLTLESKDVYELLKECNECVIMAATIGIDI
                     EKEIRRHSYSNLTKGLIIDSCGTTAIEEVCDIVQNNLEKVFLKQDKFITMRYSPGYGD
                     LPIEKNIDILNVLNAQKQIGLTITSNGIMIPRKSVVAIIGISNTRINKSKKEKSCENC
                     KNYRNCTYRKGANSCGNKTISEK"
     gene            complement(53752..54207)
                     /locus_tag="PC494_000777"
     CDS             complement(53752..54207)
                     /locus_tag="PC494_000777"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HDF3911299.1"
                     /translation="MEKVESFKLDHTKVKAPFVRKCSVLDGVKGDKVTKFDLRFLQPN
                     VESFGTAAMHGLEHLLATYLRDTLDGVIDLSPMGCRTGFYLILWGDVDAKTVKIGLEE
                     ALKKVLESDKMPAATAIECGNYRDLSLFGAKEYAKDVLDKGFSLNIYGE"
     gene            complement(54489..55670)
                     /locus_tag="PC494_000778"
     CDS             complement(54489..55670)
                     /locus_tag="PC494_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HDF3911300.1"
                     /translation="MKNKSLLNHMFRPILDLIISCALTSMLILTSMYIIKSLYVNSDM
                     SVVNQLVYQARDFRSLIGYDLFYPFLFTITSLAIYSMISYKRNKQIVDFIRKTNRKNQ
                     KLEIIKSAVNLMDEGNLEKSIDIEYDLDILKDKEKDDIDELAHKINNIVHQLRNITIE
                     ERQAQQTKTDLITNVSHDLRTPLTSIMGYLGVIEEGKYKDEVQMMYYVDIAYEKSKNL
                     NVLINDLFELTKMQNNTIKLNKIEINLVELLSQVVSQFEIYFKQEFMVSRINFNEEKL
                     IVKADPNKLVRAFENLITNAVKYGKDGHYVDIVTEKKEDMAVVKVINYGEPIPVLDLP
                     NIFDRFYRVEKSRNRNVGGSGLGLAITKNIVNLHDGEITVSSDKYQTVFEVQLPIIQS
                     A"
     gene            complement(55660..56352)
                     /locus_tag="PC494_000779"
     CDS             complement(55660..56352)
                     /locus_tag="PC494_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011948339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF3911301.1"
                     /translation="MNNTVLVVDDEKEIRDLIEIYLLNSGYNVIKAEDGKEALDILKK
                     ENIHLMILDIMMPKMDGIEVCRKVRESLNIPILMLSAKSEDMDKIQGIMTGADDYLTK
                     PFNPLELTVRVKSLIRRAYYFSGANNEDKDVIKVGVVIIDKEKHSVTVAGNEIILTSR
                     EFDILYLLANNKGRVYSTEEIFEKVWKEKYYQSNNTVMVHMSRIRDKIEKYTDGEKII
                     HTVWGVGYKIEK"
     gene            complement(56486..57202)
                     /locus_tag="PC494_000780"
     CDS             complement(56486..57202)
                     /locus_tag="PC494_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HDF3911302.1"
                     /translation="MKKFKLIGAIILVVFISVFISKDRLLKKDKDPIVAAQHDSEQDV
                     EANSQNKNHSNSISNILLVNKTNGISKNYTPENITKVNIPFVEEATEEEKQMAGEPAK
                     AVEDLVKQANSEGIQFLGSSAYRSYDTQLDTYTRRVKSQGREKADAYVAKPGYSEHQT
                     GLCIDLTNPERWFVGSTKEAKWLAENAHKFGFIIRYPEGKEDITGTAYEPWHIRYVGK
                     DAAEEIYSKGLTLEEYLQNK"
     gene            57327..58061
                     /locus_tag="PC494_000781"
     CDS             57327..58061
                     /locus_tag="PC494_000781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiocytidine(32) synthetase TtcA"
                     /protein_id="HDF3911303.1"
                     /translation="MSIQKLLSKARKAIQDFDMIQENDKIAVGLSGGKDSLTLLHILK
                     SYQRFSPQNFELIAITLNTGGVDNSPLDKLCKEINVPFYEFQTDIKEIVFDIRQEKNP
                     CALCANLRRGALNDNAKKLGCNKVALGHHKDDAIETFLMSMFYEGRVNCFSPKTYLDR
                     QDLTVIRPMVYIEEYMTKKISKDSNYPIITNPCPANGHTRREYIKNLIANLNKEMPDF
                     KRNVFGALNNSEKLFIWDKEKIKNFK"
     gene            complement(58346..59101)
                     /locus_tag="PC494_000782"
     CDS             complement(58346..59101)
                     /locus_tag="PC494_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HDF3911304.1"
                     /translation="MKKYNISENGALIKNDTIESKSESVKVVQISDTQIGSFYSTKNL
                     KKVANKINTLNPDIIVFTGDLIDYSNKNPSVDEITTILSSMNARLGKFSVFGNHDYMY
                     KLPRYYRHIMKNSNFNLLVNENKKIKLKDDKYINILGVDEILNGNPNIKYLESQIDNK
                     SFNLLLAHEPDLVDMLSKDTMNLVLSGHSHGGQIRLPIKGALVTPPYGRKYTKGFYDI
                     NGNHLYVSSGLGSTKLPFRFFNIPEIIEFNIII"
     gene            complement(59223..60161)
                     /locus_tag="PC494_000783"
     CDS             complement(59223..60161)
                     /locus_tag="PC494_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HDF3911305.1"
                     /translation="MKSILIMGGSDFIGSALAKRLIKCGYQIDILTNGKKEIDYNGFK
                     EHLICDRKVRKDMENIITGRKYDYIYDMTAYTKEDVSNLIDFISMDNLKKYIVLSAGA
                     VYKDSGRNIKEENEKGENENWGKYGLNKKEAEDFIINSPIPYIIIRPTYIYGENNNLY
                     REYYFFEKIEKNEKIPVPKGKQVSNQFIYIGDLVKVLESIMKNPHVREAYNVTNPQLI
                     SWDDLIYTCGEIIGKEPIIKYVDMEKVEFRERTYFPFRNIDFNLDINKLIEHGLYIPN
                     VLLKEGLTATYKWFSANKPKMHDRKMNKVESVMQIV"
     gene            complement(60264..60914)
                     /locus_tag="PC494_000784"
     CDS             complement(60264..60914)
                     /locus_tag="PC494_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HDF3911306.1"
                     /translation="MKKNYEIVLFDLDGTLTDPKEGITKSIQYSLNSFGIKEDLENLD
                     QFIGPPLHDTFKEYYKFEDKKAKEAVEKYREYFADKGIFENKIYENMKEILEMLYKNG
                     KILLVATSKPTVFAETILRYFDIDRYFKYIAGSNLDGTRVNKNEVIQYVLDLCNVKDK
                     DKVIMVGDRKYDIIGAKKIGIDSIGVLYGYGSFEEISESEPTYIVENVESIKDILL"
     gene            complement(61063..61251)
                     /locus_tag="PC494_000785"
     CDS             complement(61063..61251)
                     /locus_tag="PC494_000785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HDF3911307.1"
                     /translation="MKAFVDKDVCVACGACIGTCPDVFSMSDEGHSVAIEGEIPEDLQ
                     DLCKEAEEGCPVSAITVK"
     gene            complement(61358..62542)
                     /locus_tag="PC494_000786"
     CDS             complement(61358..62542)
                     /locus_tag="PC494_000786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HDF3911308.1"
                     /translation="MKNLLIRNGTIISPTDGIKFEKRDILVLHGKIYAIGLNLKEKIR
                     KEKLLTNKEFEIINADNMYISPGFIDVHTHCYKRKLPTGMDSDSIGIEKGSTVIFDAG
                     TAGPSNYYDFKKKYMDECKTEVYSFLNVTNEGLNILNESTSLDVINFDKVESIVEKNI
                     EKIKGIKVKASKFQSNESGIDIIKKSKQVAKKINLPLVVYIGEYPSYIDEVMNILGKG
                     DVVTPVYGNSTNGILKESGTLRKSVINAKNRGVLFDVCHGVDQFDFKVFKKAIKQGLE
                     PDLISTDMHIKNMKDVNYSLLNVINKIMELGISLEKCIEKVTEYPTKIFDLHGNKGRI
                     KIGGEGDFTIFTMEECNDIIKDYNNNELVLNKKLRLQYTVKSWMKSSEVYRHGYENTI
                     IN"
     gene            complement(62684..63601)
                     /locus_tag="PC494_000787"
     CDS             complement(62684..63601)
                     /locus_tag="PC494_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SufD family Fe-S cluster assembly protein"
                     /protein_id="HDF3911309.1"
                     /translation="MNKIDLNLLEKVAELRGTPLGAYNIRKNGQGVERHSTENVTIIP
                     KTDKPGIDIIVKPNTKGENVHIPVIVTEAGVQDMVYNDFEIGENADVVIIAGCGIHNC
                     GCDDSEHNGIHRFFLRKGARLKYVEKHYGEGDGEGKRILNPVTIVNMDEDSYCEMETI
                     QIKGVDSTKREMDANLGKGAKIVVFEKLLTHGNQVAESNMKVILEGENSSAQVVSRTV
                     GQDNSKQKFNPCVIGDSLCSAHVQCDSIIMGNSQISAIPEIAANHPDALLVHEAAIGK
                     IAGDQILKMMTLGLTEEEAEQQILNCFLK"
     gene            complement(63623..64351)
                     /locus_tag="PC494_000788"
     CDS             complement(63623..64351)
                     /locus_tag="PC494_000788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDF3911310.1"
                     /translation="MLEIKNLSFNVESNNEELGIINDVSLSFERGKLIVITGPNGGGK
                     STIAKLIMGIEKATSGQIILDGEDITNLSITERAKKGIGYAFQQPPRIKGMTVENLLT
                     LAHGKPLSTDVCCQYLTDVGLCSKDYLNREVDNSLSGGEMKRIEIATLFARDLKVSIF
                     DEPEAGIDLWSFGKLNESFKKIHEESNQTIIIISHQERILELADEIIVLQDGSVKSHG
                     TKEAILPEIMCQVNSSCELMKDMN"
     gene            complement(64547..64747)
                     /locus_tag="PC494_000789"
     CDS             complement(64547..64747)
                     /locus_tag="PC494_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3911311.1"
                     /translation="MFKKMAVLKDIATKIGRKKAYELLEMVEGNDAFVAEVKIKKNGI
                     ESKKEEIMLKDNQKIILEYIEG"
     gene            complement(64872..65252)
                     /locus_tag="PC494_000790"
     CDS             complement(64872..65252)
                     /locus_tag="PC494_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HDF3911312.1"
                     /translation="MINKIGKITLYVNNQEDAKLFWTEKLNFVVTYEKEMGPNMKWVE
                     VAPSKNEFTTFVLYDKNLMMKQNKEINVSHPSIILSTRDINGTYEQMANNEVEVGELM
                     EMPYGRMFSFKDQDGNDYLVREDK"
     gene            complement(65525..66883)
                     /locus_tag="PC494_000791"
     CDS             complement(65525..66883)
                     /locus_tag="PC494_000791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HDF3911313.1"
                     /translation="MFIRKNVIKLAIPIMIEQTFVMLLGVFNTMMAGHIGEEAVSAVG
                     MVDSINNIFISVFAALSVGATVVVAQQIGKKDSEKVNETIKQALVSGVILSFTITILM
                     WVFRTGVINLFYGSAEELVKSNAKLYIEFTLFTYPFIATQQIANGILRGCGDVKKPMY
                     VTMFMNIVNVTLGYILIYGIDLNPLGINLQTPSYGITGAAISIAIARIIGCIVIIRAL
                     FKGNEFISMGKIFPFKIDVETQKSIFNIGIPAGVEQLLFNAGKLIVQVFIVTMGTSAI
                     ASNAIGMSIASIINVIGNALALSATTLVGQYIGRGDIKGAKSTLLYLTKFATICLFIV
                     GAIFIPIAPWISSMYTQNASVIDISTQLIRSDCLAMVIWPISFVLSAGLKGAGDTRYT
                     MMTAVIGMWIFRIFTGYVLGVVLEFGVLGIWIGMYTDWLVRGALYCLRLRGTKWLKHK
                     VA"
     gene            67331..67783
                     /locus_tag="PC494_000792"
     CDS             67331..67783
                     /locus_tag="PC494_000792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="staygreen family protein"
                     /protein_id="HDF3911314.1"
                     /translation="MVNLNANNLNVNMVYPISSTAPIRFRRYTVSYLENMENIYLTIA
                     TYFDTLGLGTMNIDKVYGQWAWFTDNIYDLNLFVFVGNYPYQIAKNRYDTFVDILPVA
                     ITSIVNGDRVFLISNPCLLNSKITVRFISSHPTLNRTVDYGNIRDFIF"
     gene            complement(67940..68557)
                     /locus_tag="PC494_000793"
     CDS             complement(67940..68557)
                     /locus_tag="PC494_000793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF488 domain-containing protein"
                     /protein_id="HDF3911315.1"
                     /translation="MEIFAIGHSNYPYDKLINMIKKYDINCVVDIRETPYSKYNIQYN
                     KEAFNESLRNSGFIYIYMGKEFGAKRTNKDVYTQEGYADFEKVAKEDIFLNGIERLKK
                     GCQMGYRIVLLGAMQEPIRCHRSILVGKVLNKEGFDVKYIMHEGNLAYQEDIEESLLD
                     KYFSDRKQLSIDNLLGSALTREEMIQEGYKLANKEIGYRTEKLGK"
     gene            complement(68980..69792)
                     /locus_tag="PC494_000794"
     CDS             complement(68980..69792)
                     /locus_tag="PC494_000794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HDF3911316.1"
                     /translation="MFSIGMFSKINKITTKTLRYYEDIGLLKPEYVDEFTKYRYYTTE
                     QLPKLHQIITLKQMGLSLAEIKKAVENPEEVENILMNKEKEMLDVIKSEEYKIIKLRN
                     YLMNLKGEVNMNDVIIKSLPKVKVASMRKVLKGYDELFNLFPNVMAEEMMKTGCTCAV
                     PDYCFNIYHDGEYRETDMDVEMCQAINDLKEDTDILKFKELDAVENAVCILHNGPYST
                     LGKTYADAFKWIEDNKYKVVGNPRESYIDGIWNKESEEDWLTEVQIPVKRML"
     gene            complement(69868..71286)
                     /locus_tag="PC494_000795"
     CDS             complement(69868..71286)
                     /locus_tag="PC494_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium/proton antiporter"
                     /protein_id="HDF3911317.1"
                     /translation="MTELMIISGLVLLICITSSKVLYKFGVPILLIFILLGMLFGSDG
                     MVGIYFDNYELTKQLCSIGLIFIMFFGGFGTNWNMAKPVAIPSILMSSLGVIITAGVT
                     GMFCHMVIGTSLLEGLLIGAIAASTDAASVFAVLRSQKLNLKGSLASLLEVESGSNDP
                     IAYMLTLILLTLMNNSGVELIAPMVIKQIAFGLAIGFILAKLSVYILRHSNFEIEGFY
                     TIFITAIAILSYAFSEYLGGNGYLSVYISGIIIGNSRIPLKKSLVHFFDGISWIMQIM
                     LFFMLGLLSFPSKLPNVFGIAMAISIFMIVIARPLATFIVLAKFKFSNKEKLFISWVG
                     LRGAASVVFAIYAVTQGVAIENDIFHIIFFIALLSVGIQGSLIPTVARKLDLVDDNTP
                     VLKTFNDYDGEISSKLIEVNVDEGNKWANKSIIDSNIPDDILIVMIKRKEQVLIPKGS
                     TIIKTGDILVLSGDRIEELIQL"
BASE COUNT        22585 a        13115 c         7718 g        28037 t
ORIGIN      
        1 tttcgtcaat actttttttg ttttttattt taaaaaaggt tataactttt ggttttttta
       61 ataaatataa ttaaaactaa tagatataac ccttgatatt acaaacaata catgcatata
      121 taattttacc tattttgcaa ttttattttc ataagaatat gaattagctc tcactctatc
      181 tgcccaaaca tttatactct taactttatt aacattagtt gtaccctcaa aaatatccat
      241 tgcatcctta caaaaatata tcataacatc aagaaccaaa aatccaacac aaaataaaca
      301 taaaaaatta attacttgaa acatcagaca ttcccccaat aattttttat atatagtatt
      361 ctcataaatt attcttttta ccttctcata aattattcta aatattttca taataaatta
      421 ctttcaatca tattttctaa atataaagtc tcaatcaaca aaaactaata tcaatttcta
      481 acgtttgttg gtaatttata aattaaatat ctaaaagaat ctttgaagca tataaaaagc
      541 attccacact gacattttaa ataaaattta gctatttatt gataatttaa tagctaaact
      601 ttatttaaaa cttagtagaa tgctaatatt tcttagtttt cttcttcttt atttggattg
      661 ttatcaatag gtttcatagt cgggaataat aatacatctc ttatagatgg agagttagtt
      721 aataacataa ttactctatc tatacctatt cctagtcctc ctgtaggagg tagacctacc
      781 tctaatgctt ttaagaaatc ttcatccatt tcaaaagctt catcatcacc taattctctt
      841 tttctcaatt ggtctataaa tcttcctttt tggtcaatag ggtcattaag ttcagaaaat
      901 gcattagcta actcccactt attagcaaat gcctcaaatc tatcagttct tcttgggtct
      961 tcaacatttc tcttagataa tggagatact tcaactggat ggtgagttat aaatgttggt
     1021 tggattaatt tatcttctcc aaattcttca aagaaagcat ttattacttc tcctcttctc
     1081 attccaggtt ttatctctat acctttttct ctagcaactt ctagtgcctc ttcatctgta
     1141 tttatagtag aaaaatctac accagaatat tctttaacac aatcttccat actcattctt
     1201 ttccaaggtg gtgtaaagtt tatttctgtt ccttgatagt taactatcat acttcctgta
     1261 gcaacttcag ccatatgtgc aataacattt tctgttattt ccatcatatc agtatagtct
     1321 gcatatgctt gatataattc tattgcagta tattcaggat tatgttttaa atccatacct
     1381 tcatttctaa acattcttcc catttcataa actttatcaa atccaccaac aataagtctt
     1441 tttaaataca attcattcgc tattcttaaa tacattggta tatgtaaagt attatgatta
     1501 gttataaatg gtctagcatt tgccccacct gctatagtat ttaatattgg agtctcaact
     1561 tctaaaaatc ctctatcatc taagtatgct cttaatgctt ttaatgcttt tgttctaatt
     1621 aaaaaagcat tttttacttc tggatttact attaagtcaa catatctttg tctatatctt
     1681 agttcttggt cttttaatcc atgatatttt tctggtaaaa cttgtaaaga tttacatagt
     1741 aatactacag atttagcctt tacagatatt tcaccttttt tagttttaaa gatttctcct
     1801 tcaattccaa ctatatctcc aatatcatat gttgaaaata cactatattc ttcctctcct
     1861 atagcatcta gtcttacata agattggatt cttccctctt ggtcttgaat atctataaag
     1921 ccagcttttc cttgtattct cttgctcatt atacgtcctg ctatttttgt agttttacct
     1981 tcaagagaat caaagttatc ttttatatcc atagaataat gagttctatc atatctactt
     2041 tctttaaaag gatctctacc tgactcttgt aattttttta gtttatctct tcttacttga
     2101 agtacttcac taaggtcttc ttgaatttgc gcttcttcat tgctttgttg attatttttc
     2161 atttttttcc tccaaattat cttcttattt ctaatatttc aaacttagca actccatcag
     2221 gaacttgcac ttccacaact tctttcgcag ctctacctaa aagtgctttc cctacaggag
     2281 attcgtttga tattttacca tcatatgggt ctgcttctgt cgaaccaact atagtatatt
     2341 caacctcttc atcaaattct aaatccttaa ctttaactat tgatcctatt gtaacaacat
     2401 taaggtctat tttgctttca tctatgataa cagcttttct aaccatattt tctaatttta
     2461 aaattctttc ttcaacttgt gcttgttcct ttttagcttc atcatactca gcattttcag
     2521 ataaatcacc aaaagatata gcaactttta ttctctctgc aacttctttt ctctttacaa
     2581 cctttaagtt ttctaattct tcttctaatt tatcatatcc ctcttgtgtc aataaaaact
     2641 ctttattttc ttccattata aatacaactc cttcacaaat ttcttaggaa ttttcctaat
     2701 tatattttaa aaattttata atcttttttt aatttatgcg ctatattata agtcactatt
     2761 atttttatgt caaggagtct tccatatagt actccaattt cgacacaact tcttgatagt
     2821 cttctatttt gttaatttca tcccttaatt ttgcagagtt tctaagtcct tttaaatacc
     2881 aagcgatgtg ttttctcatt tcccttacag ctacatactc tccatgttct tctactgcaa
     2941 gttttaaatg cttaatggca gtacttattt tttcgttaag agttggctct ggcaaaatct
     3001 cgcctgtatt catataatgg tttattcttt taaatatcca agggttacct tgagcacccc
     3061 tacctatcat tatagcatca caaccagttt tgtctaacat atttattgaa tcttctattg
     3121 taaatacatc accatttcct ataacaggta tactcaaatt tttcttaatc tctgcaatta
     3181 tatcccagtc tgctttgcct gtataaaact gttctctagt tcttccatgt attgctaaag
     3241 cacttattcc acaatcctct gctatctttg ctatttcaac agcatttaca ctattatcat
     3301 cccagccttt tcgaatcttt aaagtcactg gcttttttga gttcttcact actgccctca
     3361 atacctcttc tgcaagctta ggatttttca taagtgctga gccatctcca tttttaacta
     3421 cttttggagc tggacacccc atatttatat cgagaatctc atttgaataa tcattcatta
     3481 tctctgctgc tcttcccata aactctggtt ctgaaccgaa tatctgaact gctacaggat
     3541 gttcttcctc ttctatctta agcatttttt tagtattttc atcatcatag caaagtgcct
     3601 taccatttat catttctgta tataaaagcc cacatccctg ttctttacaa attaatctaa
     3661 atggaaggtc tgttacacct gccataggtg atagaaaaac tttatttttc aattctaaat
     3721 ttcctatttt cattgttttt ctcctatttt tgcctttatt ttgtgattta actttaaatt
     3781 cttatttcct cattataata taccacatat agctagaaat ctatcataaa aagggaattg
     3841 gatatataac ccaattccct gtatattaat tattcttggt ttttttcata tattattctc
     3901 aatccttcta gtgttaaaaa accatctaca taatctatac ttttcgtctc tgaagcaatc
     3961 agtttagcta atccacctgt agctataacc ttaacatcat cacaattcaa ttctttcttc
     4021 atcatactta ttattttgtc aactaaacca acatatccat aaattattcc agattgcatg
     4081 gctgatacag tactcttaca aatagtcata cctggcttag ctaattctac tctaggtaat
     4141 ttagacgcac tttgaaataa cgcctcacta gatattttta ttcctggtgc tattgttcca
     4201 cccaaatatt cacctttttc agagatagca caaaatgtag ttgctgttcc aaaatcaaca
     4261 agtatacttg gtgctccata cttttctatc cctgctacag cattaactat tctatctgcc
     4321 ccaacttgtt ttggattatc atattttata tttagacctg tttttatgcc tggacctact
     4381 attaatggct gttttttaca gtactttata caaaagtttt caagagaatg cataacattc
     4441 ggaactacag atgatattat aacatcatca atatcactta tattcacatt atcataatca
     4501 aataggttac ttatcaggat tccatattca tcagacgttt tttccctatc tgttttaatt
     4561 ctccagtaat taactaattt atcaccttta tatataccta aaaccatatt agtatttcca
     4621 acatcaaata ctagaagcat atgtcattaa ccttctttct attttttgct tttcttaagt
     4681 acagtggcaa cagcagctac tactaaagcc cctactattg cttctggcac cccatttgct
     4741 gcggcaagag ccattattac ttttcctgct gaaccacttt tacccattgc atgaagatac
     4801 ttgtcagcat ataagacata tatcattcct aaaactccag ctgtatttaa cagagaacct
     4861 attgcccctg taattaaacc tgatatgtat accttatttg tagccttaat tattaactga
     4921 tatacataat aagctaatac acctatcata actcttggta atattgaaac taatggattt
     4981 ataaaaacaa aagatgttac tgttgggttt gttatagcat ttaagagact tgatatccca
     5041 aatataaatc ctattgctgc cccaactatt ggtccttcca taatagctcc aataataact
     5101 ggtatgtgca ttatagttgc ttttgtaggt ccaactggaa taaatcccaa tggagtcata
     5161 gatagcataa tagaaatagc tgatagtact cctattatag tcatctttct tacatttact
     5221 tttcttactg atgcacttgt gttcatcata aaaaatacac ctccgttcca gctcattaag
     5281 atgccggact acttaatttt ttaatttttt cgtttttttc ttataattat gagtcaagct
     5341 accattgtag gatgcccgct ctaacaagaa taattttatc aagatgagtt gccattgtca
     5401 acaatttgac aagaaaaata tgctaatttc atcatatttc tcgttttttt actatatctt
     5461 tatatgccat tatattttct acactatccg ctttttttac tgcatttatt atactttttt
     5521 ccacaacctc tacagccaat gaacctacta atgttatatc tgcttctatt tctcctgttg
     5581 atattgtgaa tattgtatct ccatcatgag gtgtatggat aggaaaaata gacttagcat
     5641 atccatcatg tcccatttga gatatctttt tacatccagc tttggttaac ttagcatttg
     5701 ttgcaattat cccaattgta gtattatcta cactaaatcc acctttactt tcaccttgtt
     5761 tcattaattt atatgtatca attgtttctg tctttttatc atttaaagca ccagctataa
     5821 ccttaccatt ttcataaaca tctccaagag catttacagc aattaatgca gatacaacta
     5881 gaccattatc taattttata gaatagctac ctattccgcc tttcatagca tattcctgac
     5941 ctcttatctt tccaacagtg gctccacaac ctgctccata atttccttga tttaaaatat
     6001 cagtatttgc aacttcacaa gctctataac ccatctttaa atctggtcta catttaaagc
     6061 tccctactcc taaatcaaat aaaactgctc ctacaactat aggcacttta cctacaccta
     6121 catcaaaacc aattcctttt tcttctaagt atctacttac accacaagtg gattcaagac
     6181 catatgcaga acctccagcc aaaactactg catgaacttt ttgaaccata tttacagggt
     6241 ctaataaatc ggtttctcta gtccctggag cagagcccct tacatcaaca ccgcaagtag
     6301 ctccttcttc acatattact actgtgcacc cagtaagacc atttctatcc tcaacctgcc
     6361 caacctttaa gccttctata tccaaaatat tattatacat atcctttttc tcctcttata
     6421 gaaacttcac ctgaaataat ttcttttata cttccatcac ttctttgaac taataaattt
     6481 ccctcttcat ttatgtctaa acatttcact agttctctat tatctccttt taatacatat
     6541 atatttttat ctataattgc agaataatct ctacatattt ttaaggtttt ttctttggaa
     6601 ttatttacag tataatctaa atataatttt tcaaattcag tcaatacatt cctaacaata
     6661 tctactctgg ataacatata cccttcttta tacaatgatg tggctttgtc agctatttct
     6721 tgttcaaaat ccattatttt aacatttatt ccaattccaa gaacaacata atttgttctt
     6781 tcaatttcag cagataactc tgttaatata ccacatattt tttttccatt taaaataaca
     6841 tcatttggcc attttattaa tgtatttgct cctagattgt ttaaagcttt cgttacactt
     6901 gctcctgcta ttaaagttat aaatggagct ttgaatggtt ccatatttgg ttttaatata
     6961 atactcatcc agattccttc atgaggtttt gaatcccatc ttcttcccaa tcgtcctttc
     7021 cccatgtctt gatgttcact taaaatcaca gtcccatcta cactatttat agctatcctt
     7081 ttagcatgtt catttgttga atctatagtg tcaagatgtt caatattttt tccaataaac
     7141 tctgtatcta atttatagta aatattctgt gggcttaata aatcagttgg attttccgct
     7201 aatcgatacc cttttttatt tacagattct atattatatc cctcttcttt taaggctttc
     7261 atatgtttcc atatagctgc acgtgacacc cctaattgtt ttgataattc ttctcctgaa
     7321 ataaattcag atttattatt taatataatc tctattattt tatctctcat atttcacctc
     7381 taatatgaca taatttcatg acttattttc ttctaataaa taattataca ttattaatat
     7441 acttttaata ctattaattt taaatttcct ttttaattat tataatggtt gttttatatt
     7501 ttatattgat gatttatata attttacatt ttatttaaat aattttaaaa taataaaaaa
     7561 actgaaagta tcaattaaat taatacatgc aaatataatt tgcttattaa tttaatatta
     7621 tactttcagt tttagtattt aatccacatc agataataat cttaaaatga ccaaggtctt
     7681 aaaactattt atctttatca gatttatctt ctaaattttt atttatatca ataacattgt
     7741 ttctttcttc ttcatctttt tctaatttta tagttaattg ttcttcaact tctttagaag
     7801 aattttcctc tgtaactgca ttttcaattt cattcagagg taactcttta ttaaatgctt
     7861 ttacaaattg ttctgcatct aaagtttcat atataagtaa agcttgtgct acatactcta
     7921 atctatccat attttcttgt aatatacttc ttgtcttatc atatgcacca tcaactatac
     7981 gctttgtttc ttggtctatc tcaaaagcaa cttcttcaga ataatttctc ttacttgaaa
     8041 aactattacc taggaatact tcatcatcac tgtcaaatga cattggacca agtttagaac
     8101 tcattccata ctttgttacc atacttcttg cagtagctgt aactctttct aagtcatttg
     8161 aagcacctgt agatacatcc ttaagtacta gctcttctgc tactctacca ccaagtaaaa
     8221 ctacaatatt ttctttcatt tcattttttg tagcatagaa cttatcttca acaggaagtt
     8281 gcattgtaaa ccctccagct cttcctcttg gaactattgt aacttgatga acaggactta
     8341 cttcttcaag tacatgggca caaactgcat gccctccttc atggtatgct gtaagtcttc
     8401 tttctttctc acttattact ttcgattttt tagccacacc tgctataacc tttgttatag
     8461 cttcttctat agtttccatc ttaattttct tttctctttt tctagctgtt aatattgcag
     8521 cctcattcat taagttctct atatcagcag gagtaaatcc tggtgttctt ctagccaaga
     8581 catccatttt tacatcatca cttaatggtt tatttcttga gtgaacttta aatatagcct
     8641 ctctaccttt tacatctggt gtaccaacaa caacttgtct gtcaaatctt cctggtctaa
     8701 gtaaagctgg gtcaagtata tctggtctat ttgtagctgc catgattatt ataccttgat
     8761 ttaccccaaa tccatccatt tcaactagaa gttgattaag agtttgctct ctttcatcat
     8821 gacctccacc aagacctgca cctctttttc taccaactgc atcaatttca tctatgaata
     8881 tgatagctgg agcacttttc ttagcctgtt caaataaatc tcttactctt gaagcaccaa
     8941 ccccaacaaa catctcaacg aaatcagaac cacttatact gaaaaaggga actcctgctt
     9001 ctcctgcaac tgctcttgat agatatgttt taccagttcc aggaggtcct accataagca
     9061 ttccttttgg tattcttgca cccaattcaa tatatttctt aggattcttt aagaaatcta
     9121 ctacctcctg caaatcttct ttttcctcat ctagtccagc tacatcttta aatgtaactc
     9181 tagttttttc atcatcttta tgaaccttag cttttgattt gccaaaactc ataacctttc
     9241 cgcctccacc ttgagactga ttcataaaca cgaaccaaat aatcaccatg aagaatatta
     9301 acagtaatgt aggcaacatt tcgacaaacc aaggtgtaga tggcttagct tcaccaccaa
     9361 aagttagttt cccagcctta gcttggtcta acacctcatc tgcaagttta tttcccatca
     9421 cttctgttgg aacatatgac ttaaactttg tatttgtatc ttttatagta ccttctacag
     9481 aagtttgatt tacaaagtat aatcttgata tattctcatc tgttaattct ctatatactt
     9541 cagagaattt taaatctttt attttttctg taggcttacc tgagaattga actataccta
     9601 ctataattat aaaaacaagt agataaaaac ctgccccttt tagcaactta ttcaatatag
     9661 aagccctcct ttcatacatt gctttgccct ataatttgtt aaaattaatt tttaatactt
     9721 cttttgtgtt ttcatcaatt ttataatttt cactgatttt ataatctcca acacatatta
     9781 ttccttcact atctgtgatt ataggaattt tacatctttc ttctcttggg atttttaaat
     9841 ctatgaataa atctttcact tttttacttc ccatagcaag ctttatctta tcaccttgcc
     9901 ttctgcttct tattactata ccccctttta ccttattaaa atcaaaccct ttagatgaat
     9961 tgtctaattt catactctta tacctatcta tgctcattac ttgggtctca ataatttgtt
    10021 ttaattcttt tattttaata aacccattac taggtacatt gtaataaaat tcaatttcct
    10081 cattaacaat ttcctcattc gttaatatta tactgtcttt ttttctataa acaaatatat
    10141 ttcttggaag agttaacatt ttatttactt ttgaattatc ttctaaagac attatatctt
    10201 ctatatgtct ttggtcaaca aaattagtat ctcctagtat atgttttatg gaatttctaa
    10261 gaactctaac tttgatagca tcatgtaagc aaacaaaatc gtctaaattt atctctacaa
    10321 agcctttttc ttttatattt gaaacttctc taaatttagc ttctgcctct ttctcaatat
    10381 aatcgttatc actttttaaa ctattgctca tcctcactat agattctatt acatttgaat
    10441 taaaattatc cttcatatat ggtaaaaggt ctaaccttat cttatttcta gtgtatatat
    10501 tttctaaatt tgttttatct atcctcggat ttaaattata agcttcacaa tactcctcta
    10561 tctcatttct ttccacgtct aatatgggtc taattatgca attatctcta atataatcaa
    10621 ttccctttaa accttttaaa cctgttcctc tcatgatacg catcataacc gtttcggctt
    10681 ggtcattgag attatgacct attgctattt tattggcttt aatcttatcc ttaatttcat
    10741 aaaacatttc atatcttagc ttccttgctc cttcttctaa tgataatccc tcattttcac
    10801 aatattttgg tacattaata gactttacaa agaatataat tcccatatcc tcacaaagtt
    10861 tagatacata taatgcatct ttttgagctt ctatccctct tatttgatgg tttaaatgtg
    10921 ctgcatatat ttctatatta aaatcttttt ttaatctatt tagtacatgc aataaacaaa
    10981 ctgaatcagg tcctccagaa agacctaaaa ctattttatc gcctttttgt attaaattat
    11041 gtttatttat agtacttagt accttatcaa atatcatatt tatccctctt acacttagtt
    11101 ttattcactt ttaagtatac tttctataaa aaaacgctaa acccttgtat caattttaag
    11161 aaattaaagt ttaatataaa tataataata ccaaataaat taaataaaag gtagtttttt
    11221 cactaccttt ataaaatttc tggaaaatag ccatagttat tatttagtac ctatgtatat
    11281 atctatttta ttcctaccta aaaataaatc ttgtaccttt atattatagt ctattttcaa
    11341 ttttatgtgt tccccttctt gtatatttat atctaattct cttgtatcaa tatcaattaa
    11401 taaagtacct tgtggggtca catactttgt agtactactt tctccacatt taaacagcat
    11461 tgttgagtta atagcaccaa actttttgat actaacttga tttttgagta tctttatagt
    11521 attagttatt tctatatctt cttctttttc cttgtaaata acatatattc catcattttt
    11581 ataaaaaatt ttaccaaagg cagtcatctc tatggtgtcc atatttcctt tttcatcata
    11641 ttgtctagta tttatactta tttttacact caacgatttt tcctccatag attcttcata
    11701 taaactagta tttttgtatt tctacttttt gaatcttatc aatttttttc tttaagaact
    11761 ctcttgctat atctgaaaat ttttcaggta tatctgatac ataatattga taagttccat
    11821 gaatttctgt attgtttata atattttgca cctctaaaat cttttttaaa tcctttgcag
    11881 tctctttagc tggattaaca agttttatat gctctccaac ttcttcacct attgttctct
    11941 ttaaaatagg ataatgagta catcctaaca ctaaagaatc tatatttttt tctttcaatt
    12001 cttgtaaata tatctttgct gtcaatttag ccacttctgt atttgcccat ccttcttcaa
    12061 caataggcac aaataaagga catgctttat taacaatttc tatactctca tctattttag
    12121 atatttccaa gttgtatgct tttgaactta tagttccttc agttcctatt attcctacaa
    12181 ttttgttttt tgtagaactt acagctgttc tagctcctgc ttctataact ccaattatcg
    12241 gtatatcata tttttcttga gcttctttta agcttcttgc agtagcagtg ttacatgcta
    12301 taactatagc ttttacacct tttgttttta aaaagtttat agcttgaaaa gtatatttaa
    12361 ttatagtttc tttggatctt gaaccatatg gtattctggc agtatctcca aagtatatta
    12421 tatcctcatt tggtaatatc ttcattatct cttttagaac tgttaatcca cctaatcccg
    12481 aatcaaaaac tcctattggt ttattgttca tctttataca acacctactt tacatttttg
    12541 tgtttaacaa caacttattt atcgctaaaa tttatattta tattcataat taatatatta
    12601 ttacctaaat gattattata gtttatttta cacaaaaaat aaaggagcta tcttaaatta
    12661 gaaaataatt tctacaaaaa gacaactcct ttcactactt aaaaatttaa atttattttg
    12721 caaacacatg atttcctatt ctcatataag gattcaatct atttatccat ttgcaagtgg
    12781 ctatttctgg attccaaaaa tatactgctt tattagttgg gtcagttcca taaagagctt
    12841 cctgagctgc tttacgtgct gagtctgttg gtgccatctt tattgaacca tcaagcacaa
    12901 ctgagaaagc atttttttga tatatgactt cttctattgt gtctggaaat ctagggtcca
    12961 atactctatt tattactaca gctgctacag caacctgtcc ctcatagctt tctcctctag
    13021 cttctcctgc aaccaactta gataataaca tcaagtcatt atcagataaa tttattactt
    13081 ctttctttgc tatatttttt tcttgtttgt ttactttctt aatattttct gttggttcat
    13141 atgcaaatac ctctttaata ggcataaata taaaagtcaa agctaatagt gtagccatca
    13201 gtttactcca cctgtccatg attaaaacca ctccttacat tcttattttt aaaatttttt
    13261 ctctaaatcc ttgactactt caagtacttt aaacttaatt tttactctac ttgttttttt
    13321 tggtgtatct tgttttatta acttatattc tttatcagtt aaaacttcct tcaacttatc
    13381 atctgtagat ttatctatca ctccattaga ttcatcaaca aaacatagtg gagggaacat
    13441 aacacaccac cagttttttc cttcaccttt cccaatgata atctttaatg ctttatattc
    13501 accagctgga agaactatat tagaatattg tttagtaggg aaattgctat attgtatacc
    13561 tacctttaca ctgtaattat atccattttt aagaataata tttttactta tttcttccag
    13621 actactatat tcctttttta taatagcttc actttctttt atactttttg aattttgaag
    13681 ctttggctgt aaatatttta ttacttcatc tctaactttt agtttaagtt cttggtcttc
    13741 atctgtattg ctgtttgcta taacatgaaa tcttattaat ttatctttat aatcttttga
    13801 tatattgtct acttttttta cctcaccatt tattactatt gtcattattg atatgactga
    13861 tataagactt aatattaata gtcccaatct aatcttaatt tttctcattg aaaattcccc
    13921 ctcaagataa atttatatca tcaattatgt ccaattaaat ttaatttatt cataatattt
    13981 tttaatacta ataaaaaaag ctatcttaaa atgattacaa tcattttaaa atagcttttt
    14041 aaaccttata ttttataagt ctttactaat catagcctta tctatcataa actgctctgc
    14101 tttttctata tgctctgtag catacttctt ggatagctca ctatcacctt taattatagc
    14161 atcaagtaag tatttatgct cttcaacaat attatgtgat gtatcataag cagacatata
    14221 ggtaactcta aatctatata cttgttccca caatgagttt attaattgga ttaatttttt
    14281 attattagtt gctttaaata tacattcatg aaattctaca tcaagtttta ataacgcatc
    14341 tacatcggat tccaaagtgc tttttttaaa ttcttctgat atatctttaa gctttttaat
    14401 atcttcatca ctaattcttt cagcggcaag atatgctgct aagccttcta ggcttgctct
    14461 tacttctaat acatccataa tatcctttaa tgacatattt gccacatacg caccttttct
    14521 aggcaacata acgactaaac cttctaattc aagctttctt attgcctctc tcactggagt
    14581 cctacttact cctaattgtt ctgctagttg cacttccatt agcctttgac caggctttaa
    14641 ttttccttct aagattgctt ctcttaaatt ctcaaagact acatctctta atggcttgta
    14701 attatccaag ttcagtttag ttaaattctc cacaaatttc aacccctttt tgactgctat
    14761 taacaacata cacctgttta tattttttta ataattcttt ttttccaatt agagcatctt
    14821 ctttattttt aaatagtcca aaaactgtag gaccacttcc actcatcata gaacctaaag
    14881 cattattttt catcattact tgttttatat cacttatttc tttgtgttta cctatagtaa
    14941 cattttcaag aatatttacc atgctttctg atacagcttt tatatcttca gattttaaac
    15001 actctatcaa atatttatta tttggtcttt ttttaatatt attcaaatct aatccttgat
    15061 aaacttcttt agtagaaacg aataagtctg gtttgcatat caatatattt gtatcacatg
    15121 gtaaaccttt gatttttgtt agcttttctc caataccttg agctaaggca ggtcttcctg
    15181 atatacaaaa aggaacatct gcgcccaaat taagtcctat ttcttttaat tcatcttcag
    15241 ataatctaag ttcccatagg tgatttaaac ctactaatac tgcggctgca ttagaacttc
    15301 ctccagccat ccctgctgct acaggaatat ttttttctat gaatatttct acaccttttt
    15361 ttatataaaa tttattttta agtattttgg cagctttata aacaatatta tcttcatcta
    15421 aaggaatatc taaactagtg ctttttacct ttatttcatc ttcgtctaat tcttttatct
    15481 ttactatatc gtataaatct atcgtttgca ttatcatttc aacaaaatga taaccgtctt
    15541 gcctttttcc caagacatca atggataaat ttatttttgc tctactcttt agtcttataa
    15601 aatccattct atcctccttg tttaaagaat aatgcatcac taacaataat attatactac
    15661 aaaaaataaa ataatagggt attataatac cctattatac ttaattactt taaatttttt
    15721 aatattaatc tactaatacg actttttttt ctaaaataag acacttacca ggcttaattg
    15781 gttcatcaag ttttatatca ttaagttctg caatttcatt ttctgttgta ttgtattttt
    15841 ttgctatatt ccagaaagta tctccttctt tgcatatata tacgattatg ctaggagctt
    15901 tagataaatc atatacacct tggtcttctc ccttgataat aaaattttct gctttcttat
    15961 ctaatgcttc agtaaatctc ttaattttga taatcaagtc tatctggtcc ctattcaaat
    16021 caacttcgac tttatcaata catgctgtat taaacacaga tgctgtatca gttagattat
    16081 ccatttctat atcatgttca aatggaattt cctcactaat tttataaacc aattttaaac
    16141 cttcaactgg gacaaataaa atttcaactt ttatgattcc ttgtataatg cttttatttc
    16201 cttcaatata actattttct atagacatgg ttggacaaac gcttacaata tcttttattt
    16261 gtatatcatc attatcattt cttatgcctt ctctaaccat aaatgtttct tcactacgtc
    16321 ttaaagtctt atttaattga ataggtttgt ggtcaaattt tattatcttt tgaggcgaat
    16381 atgcatcttg taatacttct cttgtaactt catctgtaac ttttacctta caacaagcca
    16441 tacaatctat ttctaaaaga cctgtgttgc tttcactatt ttgcttgaaa atatgattaa
    16501 aatctgacat agacaacaat acttcttcag tcataccatc actaactcca gggacttcta
    16561 caaattgagt aaactcaata cctactctat ccaactctac aagttcaccc tcatatgtac
    16621 aagctaacgg atttatttct aatactccac caataataac tttattgtca gtcactctac
    16681 tttcttttac tttaacacat ggatttaaac ttattataga ttgaatttcc tctgtgttta
    16741 ttgttatagt atctcttata gaactttctg ctttttctat tccaactata tcttgaaaac
    16801 aaatttcctt tctgtgcttt tgtatgcctt ccacttgcgc cacatctttt acaatgtcta
    16861 acctttgctt ttcaaacaaa cttcccctta tattcataag agctcctact ttaatctttc
    16921 tctcattcat tatagtacaa tccatatgct ctacttctga aaataacatg tattccatat
    16981 cttgaacaac attgtctttt tctattactt cgtttatatc tacttttccg tctacattag
    17041 aaatagtatt tttatcatct gcaatataga ttacattata attaaaacta cctctgcaaa
    17101 gtatcttccc atctgccatt tcaatttttt taagtgatat gtatccttct gtttttacaa
    17161 tttcatatac atctaatttt ttgtctggta caactgcctc cgcttcaatg aatgtttgaa
    17221 attttccaaa gtctattcta ttgtcaactt taattacatc tttaattaat tccatagtct
    17281 acctccttaa gtattataaa aatatcacac tatatttata tttaaggagc aaaaaaaaaa
    17341 ttacacctat ttttaaatag gtataatttt aacttatttg taatttatct tgatctctaa
    17401 aaacttgcaa ctttacatta gatgttaata aatctgagta actataagat actctaggat
    17461 atccattact ttcatcatct aactttataa caaacacgct tggataaact ttttctagta
    17521 taccctcttt tgtaataatc tgctttcttc ctttattagc tttcaacaat attttctttc
    17581 ctatatgtct ctctaagctt actcttatct tatctagagt ttgaacagta gccacaatat
    17641 caccttcttt aacgtttata tgtttacata atatcacata taaacatttt tgtcaaatgt
    17701 ttaaactaat tattttatat attttttgca aaaatgtcaa tactattttt gaagatatac
    17761 agtataatta tgttaatttt tgctaatgta atattgtttt tggcattgcc catctaaatt
    17821 ttcctctggt ttcagaacca ccaattccct taacacctgt aatagtctgc tctataacct
    17881 catcaatagg aactactaca tcaattcttg aacaagcaat tttctccact ataaaaacag
    17941 ggtctaatgc atgtatcatt atccttccag gcgaacttgc atagtttgct cctgcactta
    18001 ttattttttc ataatttgat tggcatgctc ctgcgaatat gacaagatta tccaaatttg
    18061 gttgccattt acgtgcttct tttactgttt taacaaaatt tgaagagttt ctatagttac
    18121 tcatatcttc tatatctcct ctttttattg tcattgcatc atgacctgtt attactagta
    18181 tatccggatt atatttttct agtagtgctc ttacttcttt atactgattt tgctctgaaa
    18241 cagctacacc tactgcaggt attccaagtt gagcatatac atccaagcaa atttttaaat
    18301 attctttatc tccatctatc tgtagtactt ttccaggcat tccatatgtg ttaggattta
    18361 attgaagttt tggaactgct ctagtcattc ttttttgtct ttctttagct tttcttactg
    18421 acttatataa taaattttct acatttttat ctattaatat atcttttata tcaggtgctt
    18481 ttactaattc taggtcatca atataagcat ctgctattac tctaaatgca attcccttta
    18541 gtatagctat tttctcatta ttttcatcta caccaaaaga gactatttta aatactatat
    18601 ctttgttatg tgactttcta gctacaatgt ctcctacctt catagttaaa cctccaataa
    18661 atttttatct tagtttatac tatgttcgat ataaaacttt gtttcctaat gtcaaaaaaa
    18721 catttcttat aatacttctt ttatcactct taaagcattt ttatagtata tcttttctat
    18781 atcatcttca ctaaaccctt ctttttttag aggttcatac agtttaccca tctgagatat
    18841 atcttcaatc tcaacttttg aatctattcc atcaaaatct gaccctagag atacaacatc
    18901 tattcctcca acatttacaa tatgttttat gtgtctaacc atatcttcaa gtttactttc
    18961 acttttatca cttaaaaata agtggaagaa gtttatacct gtaactccac ctttatttgc
    19021 taatacttta atcatatcat cagttaaatt tctagaatga ttcatcattg ctcttgaatt
    19081 agaatgtgta gcaattattg gtttagaaga aatctttgca atttcataaa atccaccatc
    19141 tgaaatatga gaaacatcaa ccaacattcc caattcattc atcttatgta ccacttctct
    19201 tccaaaatca gtaagccctt tttctctata ttctacttta ttatgaggaa agctcaattc
    19261 attcacatga ttccaactta ttgtcatcat tctaacccct aagtcgtaaa atttctttaa
    19321 attttctaat ttaccttcaa gtactgcacc ttcctcaata gataaaagag ctgtaagttt
    19381 accttctgat tggtttttca taatttcttc atagttagta gctaaagcta tttcatcact
    19441 attttttttc atttcctcat gaaatttatt tgccatactc atgcaataat caaaaggatg
    19501 ttttacttct tcagtatcaa caaaaagagc aaatgtttga gctaatgaat cccccttttt
    19561 caatctgtct atatcaacag aatatttatt agacttaagt tcacttgttt ctacattttc
    19621 cattaatttt gctatagtat cacaatgtaa atcaataaat ttcatattta taccccctgt
    19681 atattttata tttatatcta aaaatagaaa tagttgtcct tatagacaac tattgacaac
    19741 tattttttaa tattcttttt aatattactt aatcttattc ttcttttaag ttaggtatta
    19801 cttttttaac ttcttcaatt tgatgccatg ttttatctat attattttca ctaatatatt
    19861 tttttaaatc agttaaagat gtaaaatctt taactgataa attgtcatca tcatctgcaa
    19921 atcttaaaat aaacatgaga ctcccttact ttccacaaca tttcttatat ttttttccgc
    19981 ttccacatgg gcatgaatca tttcttccta tttttgcttc tttaactatt gttttagact
    20041 tcttataagc ctttattatt tcttttcttt ggtctgctgg tagtatatct tcccaacctt
    20101 gtaaattata tagccaatga gcctcaacag ttaccatatt gttatataat ttttcccaat
    20161 ctatttttat agaaacttct ttatcagctt ctacttcttc taaaactata tcttctttta
    20221 agctttcact tattccatct atgaatccca tgaaaaattc attagtagtt ccaaattttt
    20281 cagccaattc acttacttta ccttcaacaa catccatttt attatttaat atttcattgt
    20341 atattccagc ttcaactttc aaatattctt cccagaattt tacttctgct tcttgacttt
    20401 catgattatc acttaaattt ctccattcag tatataaact catacttttt cctcctaagt
    20461 atacctatat ttttatagtt tttatagtat aaaatctttt agttagattg gaagtttctt
    20521 ctttttgatt ataccatatt ctatttaaag ttaactctta tattatatca taattaaaca
    20581 attcttttaa tacttttata gcatactctt ggtttataaa ataagggctt gtcgcaattg
    20641 ttattacttt ggctttttta attaagtttt ttatcttgta aaatttgagt tcaaatggta
    20701 tatagtccat atcacttgaa aatatatcca aatctatgtc aagaacaaac tctgattcta
    20761 cttctaaatc aaatccatat agactatcta ttattattaa ttctgaaaat atgttatatt
    20821 ttaaagcagg ttttataaaa cttcccacat ttaaaacttc atttgtatat ctaaatacat
    20881 cttttagatt atttacatct acatcatagt tctcaggttc tctagtatcc ttatgttggt
    20941 ctacatgcac taacttgcat ccttttgtaa actcaccctt taacaaagac tttgcccaaa
    21001 aataaaatgc atggttatga ttgtcaaaca catatatctt tttatttccc aggacatatt
    21061 cgaccatatt ctccaatcct tttgctttta tttccttatt ttcatctact tcattaaata
    21121 ctacctcatt gcctaacctt acatcattta atgtaccatt tataagtttt ggaacgtata
    21181 tgctcttatt ttctctttta tcatatgaaa atacattatt tcctactggt ttttctatat
    21241 aaaatccact atattcataa ttttccataa aactttattt cctccattgt tatataaata
    21301 tataagttat aattttaaaa attaaaatgc acttattgta aatcatatca tctattatag
    21361 aaaacatctt atataactaa atataatatc ttctctcaat atgtattata caataagtgt
    21421 aaaatatatt tatataaaat atactacatt cctataacaa aaccatcagc ttcaattgga
    21481 agataactaa ctcttctatt caactccacc tttccaaaaa atactaccca atatggtcta
    21541 aaaatacttt caattttaac tatttcaatc tctgggattc ctcccataaa cctatgagtt
    21601 aatctcatag ccattttatt tgcctttgct tttactcttc gttcgtcctt atcactatac
    21661 tgcacaatat tacaatccac attttttaca acttcatatg taggaaaatc ttgtactata
    21721 ctaccagaac ctgtagaacc attcactaaa atttttaatt catttatata attagaatat
    21781 ctcctattct tgaaaatgga tttcgttttg tgaattttaa gtgtgataat tttaaactct
    21841 atataatgaa gtctaacttc atgagcatat ttgttcttta atattagctt actaaataaa
    21901 gaattttttc cacttttagc tatctctata gcttcttctt ttgtaattct tataggtaac
    21961 gctcttatat ccataaaatc attctctttc ttattttttt cttgtcattt ttaaaactct
    22021 atatatataa tcaaaaaata ttacaattac aactgacata actccatatg gaattatttt
    22081 tccaactata atatcatttc tagtcaatat accataaaat ataaatcctg ttattaaaaa
    22141 gtacaataat actagaaaac cgtctattcc aagccatttt atttctaaat ctttttttac
    22201 cttagacact aatttagaca tagcagtttc tccttttata gattattttg tgtatttaaa
    22261 ttttcaccta ttctattacc aatcatccat gcaataaatg aaaaaggtat agctatcaca
    22321 agaggctcta actcaaagct ctgaactgga aatattttaa aataaccaaa agtcactcca
    22381 ccaacaatca ttcctaaaat accacccata gatgttcttc ttccatttcc aagaagccca
    22441 cctactatag gtacaaatgc cgaacccatc caaatacttc ctacaaatat acatgcatca
    22501 tatacatttt caaatctaaa tgctacgcta agccccataa ctgctgctaa acatacacct
    22561 attctagtaa actttactaa ttgtttctga gataactctt tttttgtaat tcttccatat
    22621 atatcatttg ctaatgtagc cccagctgct agataatagc tatccaatgt tgatattata
    22681 gaacctaaaa ttcctattat aaatattact cttattcctt gtggtaatgt atctaaaact
    22741 aaagttatat atccagcagc tggagccatt tctggataag tagctcttac tataagtcct
    22801 gtcatagtta acaccatgtc aaaacatatc catagtgaaa aacaggttaa taaggctctt
    22861 cttccaacct taggagaatc tgctgctgaa aatctttgat aaaaagttgg gtctgaataa
    22921 gctccaaaag aatatacaat taacatcaat gctttcatag ctgacatacc ctttgtaggg
    22981 tgcataagct gtggtgcatc tttgagtgct tctgtaagac cttgaaaccc tcctatttgt
    23041 tcaaattgac ctggcataac catagttaaa ccaaatacca tacaaaaaaa caataccata
    23101 tctgtaatgg caactcccat aagcccacca agtactgtaa gtacaacgac tactcctacc
    23161 attattaatc ctattaattc tttatctatt ttccatgcta cgttacctat agttcccata
    23221 gcagttattt ctccaagttg tgcacaatat ataaacatca aaattgcccc aattatagca
    23281 acatgcttgc cataaaaact ttccagtaaa tcaggaactg ttatattggt tcttatatga
    23341 atccttggac caacccacaa tgctaaaggc attctcccaa tatgtgcagc tattgaccaa
    23401 actgcccatg cagatattcc atatatagcc gcatactcta cactacctac tgtaccaact
    23461 cctccatacc atgatgcaac caaagttcct actattaagg accatggtaa acttcgattt
    23521 cctaggtaat aactttccat atcttttaca tttctagaaa aataataacc tattcctaat
    23581 aatataaatg caaatataac tataatccca ttttcccaaa atgttaacat atctaatctc
    23641 cacattctta tattttaatt tttaacttta atatctaaat atgaacaact ctacccattt
    23701 ccataaaaat aggtagagtt atataataat tataagtatt taagtaatct tgttattaag
    23761 caattttatt gtttaaacct ttattttctc ttttatttat tttatttaaa gcataagtag
    23821 caaatatccc tataactgca catactacag ataaaataaa tatatatgta tatcctgttt
    23881 gtccatattt atctaaccaa ttacctgcaa tagtgtaata aaacgcatct ggagaaaatc
    23941 ctataaatga agcaaatcca actactgctc ctgtagtttc taaagatata ttagactctg
    24001 aaacagatgc aaagtatata cctctaaatc caaataaaat tacacttagt attatcatgt
    24061 ttattacagc tatccatata aatcctgtac tcttaggaat aaccaagtaa gcagctgtac
    24121 ttactgtcat taatataaat cctacaaaca ttactcttat agatgaacca actttatctg
    24181 ttataacacc agcaactgga gatgctccca tttttataac ataagttctt attattgata
    24241 aagcagaaac tagagtcatt ggcattacat aaacttctga taagtatgga cttaaataag
    24301 ttaaacttga gaatactaaa taagttgaaa atattataag accaattagc caagcctttg
    24361 gcattgtaac tacttttaac aatgacttaa tacttaatcc ttcatctgat gctccactat
    24421 cttttttctc ttccactaag aaaaatagaa gtataccaca tattatagat gctgcagaat
    24481 ataaccatac tacatatttg aatcctactg ttatttcagc aaatttacca aagaagtaaa
    24541 gacctataaa agaaattaat gtacctgata cacctgataa cccttcataa aaaccaaata
    24601 ttcttccttg ctctgactca cttccttgca ttctaacaac cttaacagag gctgagaaga
    24661 aagttaatat tgttgtaaat ccccataata caaatattaa aagtatcata ctatatgatg
    24721 ggaatgtaga gaaataaaat ccaagtattc ctgaagcaat taaagaaaaa gttattaatt
    24781 ttctaactga gaatctatct gcaaaccatc ctcctataaa ataagatacc attcctacta
    24841 atccatataa actcaataag ttccctattt gtgtatgact taatgctaaa gcttgttgca
    24901 ttgggtcata aaatgatgat ttcatatatg gtaaactata catagctgtt gttccaaatg
    24961 ccaatatgaa tattatcaaa aatcttttaa cattattttt gctttccatt gattctctct
    25021 ccttaaaatt ttattgttta taatctcatt catataattt tattttaatt tttctattgc
    25081 ttgtttaaaa tcatttatta tatcatttga agattctaat cctacagcta ttcttattag
    25141 attttcccca ttcatttgaa ctaatgtatg ctcttcccct aagcttgttg ctattgttgc
    25201 aagctctaaa gaattcatta atcttctact agcttggtct cttgtcaatc cattgatacc
    25261 atccttaagt ttaaatgaaa ctacacctcc acctaaacca ttcatttgag ttttacaaag
    25321 ctcatattga ggatgagatt ttaatgctgg atactttacc aattccacat tctcttcttc
    25381 ctctaaaaat tctgctactg ctaatccatt ttcacaatgc tttttcatcc tcatatctaa
    25441 cgttttcata ccccttaaaa tcatccatgc actcattggt ggtaaagatg ctcctgtaaa
    25501 acaacataaa cttggccatc taactaaatc tattaattct tttgaacctg ctactgctcc
    25561 ccctaaagta tccccatgtc catttataaa cttagtaaga ctatgtatta ctaaatctgc
    25621 acctaaatct attggtcttt gtacaattgg tgtcccaaaa gtactatcaa ctatagctaa
    25681 gcttttattt tcatgagcaa tttctgctat tgtttttata tctactaagt ctaatgatgg
    25741 atttaaagga ctttctatat aaactatttt agtatttggt ctcattgctt cttttacatt
    25801 ttgtggattt actgcatcta caaatgtaac ttcaactcca aatttagata acaactcaga
    25861 catgaataat ttagtgtgtg aaaatattcc atctgaacta actatatggt caccactttt
    25921 taccaatgct aatatagtag atgttattgc ccccatccct gatgtactag atatggcact
    25981 ttctgcattt tcaagcatag ccaacttagc ttctaactct gtaagagtag gattacactc
    26041 tcttgtatac acatatcccc atgtcataca caactcttca aaatgctcta ctgtctttgc
    26101 agcaaatgtt gctgtttgac atattggtgt agccaatgca cctgttgttg ggtctgcact
    26161 atgtccccaa tgtattattt ttgtctctaa atcttgatta atattgttac tcattttgat
    26221 ttcctcccat tttgacttat ttatacaacg ttttccctac caaatttcat caatttagct
    26281 tagtcttaat acattttttc aagtatactt ttttatttgt tataatttct aaaaatatga
    26341 cacttatttt gtttttttac agttctaatt ataaactcta tagtaactat agagtcaata
    26401 tgtttttgat atttttttta caatgtttaa aatagtcagt acaaaaatag gtatatctta
    26461 gaataactaa agtcatccta agatatacct atttttatat cacaatataa ataattacat
    26521 ataagcatta gtttttttat cataaataga tttttcaaga tttatcatct tttcataaat
    26581 atattatagt taaatatttt aatattacct aacatctaca ataaaatata ctcttaaaat
    26641 aaaattatat aattaaaaat actctataaa agctaaaaag tttttctatt cgctacatct
    26701 aaaaataatt agatagaggt ataaatgtat ttagtttatt tatacctcta gtcttttata
    26761 aattatatct ctactaaatt gattttttag cacgaataag tgtgctcttg gagataccag
    26821 tcatcttcac aacctctcta tatggcttag aatttaataa ccccaatgca tattgtatct
    26881 gttgattgct gtatttcttt ggcctaccat ctttaaagtc ctttttcttt ttagcaaatt
    26941 cttttcctaa ttgagtacgt tctattatca tatttctctc aagttctgca actgcaagta
    27001 atgtagtcaa aaagaattta cccattgaag tattttctaa aaggcctata tttaaaatat
    27061 gaacacttac ttctttagca aataaacctt ctattagttg tattccttct gatgtacttc
    27121 tagctagtct atccagctta gttgcaacaa gtaagtctcc cttttttaga gatgatataa
    27181 ttttttcaaa tttaggcctg tttgtagtag tgcctgtata agtttccttt attattttag
    27241 catcattata tttattcaaa atttcttgct gttgctgata caaactgttg ttgtctgttt
    27301 gattttttgt acttacacgg caatatccat atataataat catcacttcc taacataaag
    27361 attttgtaca gaagttaccc agaagcttgt ttttacttat ctttatccat tttactaaaa
    27421 cgatttttgg gtgtcaatac tgttaacttt tgacaccata ataattcctt tataatttgt
    27481 ttgactatgt caaaaattac caatataatg aaattaatga gtttatacaa attggaggaa
    27541 ataatatgaa tagtctgtta aaagaagcaa tagatgaatt aaaaaacatc cattgcgggg
    27601 aagttttttt attaaaagaa ttgttcaaag gctatgaatg gaacaggttg gagatgaata
    27661 tcagattgaa attaggaaaa ctttttttgt atgaagtggt aactaatccc aatttaaatg
    27721 tagaggtcat caataaaaat tctgcttatc agcaaatgta taaaaaaaaa tagtgactta
    27781 aatgtatata atagtataat cttcttattg attcaaaagt taaaactttt aatacaaaac
    27841 aatcattcta ttttaacatt tatcaatatg tctaaattta tataattaac acatacgaat
    27901 agtattgttt aaatcacatt atttaagata gataaatctt aaccctactc cagcataaat
    27961 actaaaatag ggcttagaat tatctatatt tttatcccat aaaatgctta gctcttcctc
    28021 ttgattgaac atatatatct ggggaaatac aatagaagcg taaatttata aaatttccaa
    28081 agtcagaaaa cttcagttca aacttaggta taccaaaact ttcaggtgct atttcgtcaa
    28141 cgccaaaata gatgataatt ccattatctg taagataaaa tgcttggtct tcaggtataa
    28201 ctaactcaac attagaataa tacatttctc tattttcatt tatttgagat ttaatgtaat
    28261 cagtaattat attaatataa tcaactccat ctctaaaaat gtcattaagt aaaagttctt
    28321 ttccagttgt caaatctata ttgtaattat tcaatgtatt gtatttaggc ccatagttat
    28381 tagcaaaccc cataaggttt aatatcatac tcagtacata atttttatta aaagtaactg
    28441 cgtaactggt agatacccaa tagctttgtt ttggaagtga attttgagaa gttgcgttat
    28501 tatattctcg ttcttcttcc tgtaagccat ttttaaaatt atttacagtc attcttacag
    28561 cattgtttat gttatttaaa ataactgggt ttacatacgt ggattgattt ctaatattgt
    28621 atataacagg atactttaca tcatatgaaa aatacttact tctttcaaaa tcttcattaa
    28681 attgtacata taatatatta tatgtacagg tatttgtaga ttgataattt tccattaaaa
    28741 tcctccccct tttataaaaa aatcagatac aatataatat gcttaaaaca gtaataatgt
    28801 taatggtaaa tgtaaagaat agaaagtatc taaaacagca aaaaatgact aattttgtgg
    28861 tataatacat aggattgaga gttattttat aggaggaaaa atatgttatt attagcagat
    28921 aaatggaaag attatgaact tatagatatg ggaaatggag aaaaattaga acgttgggga
    28981 agttatgtac ttagaagacc agacccacag gttgtatggc caatggaatc tgaatgggct
    29041 ttatggaaaa accctcatgg acattatcac agaagcaata aaggtggagg tcaatgggaa
    29101 cacaaaaaaa gatatccaga acaatggact ataaattata aaaacttaaa gtttcacatt
    29161 aaaccaactg gctttaaaca tactggatta ttcccagagc aagcagctaa ctgggattgg
    29221 atgatagaga aaataaagaa agctaacaga cctataaaag tgttgaatct ttttgcatat
    29281 acaggtggag ctactgtagc atgtgcatct gctggtgcag aagtatgtca tgttgatgct
    29341 gcaaaaggta tggttaattg ggcaaaagaa aatatagaat tatcaggtct taaaaatcaa
    29401 acagtaagat ttatagtgga tgatgttgta aagtttgttg aaagagaaat aagaagaggt
    29461 aaaaaatatg atgcaataat aatggaccct ccttcttatg gaagaggtcc taaaggagaa
    29521 gtatggcaaa tagaagaaaa gttatacagt tttgtagatt tatgtatggg agttttatca
    29581 gataaccctt tatttttctt aattaattct tatacaacag gattttctcc aatagttctt
    29641 gaaaatgtat tgtctacaac aataggtaaa aagacaaata caggagatat atacggtggg
    29701 gaattaggaa taccagcttc cagagatggt aagatacttc cttgtggtat atttggaaga
    29761 tgggagaaaa aataatgata aaagtcatat atgaagataa ccatttatta gttgtagaaa
    29821 aaccagttaa catattgtct caaggagata atactaatga taaagatatg gtaaatcttt
    29881 taaaagacta tattaaaaaa aagtataaca aacctggaaa tgtatatatt ggtttaatac
    29941 atagattgga tagaccagta ggtggagtta tggtgtttgc aaaaacatca aaagcagcat
    30001 ctagattgtc tgagcaggta agaagtaaga ctttcaaaaa aacttatcta gctgttgttc
    30061 atggcaagat aaaatctaac tcagatatac taaaagattt tttatataaa aataaaaaaa
    30121 ctaatatggt aactgtagtg aaaaaaagcc ataaagatgc caaagaagct gaacttaact
    30181 ataatgtatt agattttaaa gaaaatctaa gtttagttca agttaattta aagactggtc
    30241 gttctcatca aataagagtt caatttgcaa gcagaaaaca tccattatac ggagaccaaa
    30301 gatatggcaa agaaataaat aagattggac aacaaatatc tctttggtcc aataagatag
    30361 aaatttgcca tcctactaca aaagaaaaaa tggaatttac atgtcatcca cctgacaaat
    30421 atccatggaa tatattttaa atctcaaatg aggtgattat atgagtaaaa aattttcaat
    30481 aggagaaatg tctaaacttc ataaaataag catacagaca ctaaggtact atgaccaaat
    30541 agatttattt aaacctgttc atgttgacca agaaagcaat tacagatatt actcaattga
    30601 ccaattttca caattagata ttataaaata tttaaaatat ttaggtatgc ctttaaaaga
    30661 aattaagtca aagcttgatg aaaataatga agaaattcta aaattactaa caaataaaat
    30721 taatatagtg gatgaaaaaa ttaaagaatt agagcttata aagaaggtac taagcacaaa
    30781 gaaagaaact atggaaaaag gtatgaaagt agatgaagtt ggtaaaatag tgagaaaaca
    30841 tattccacga agaagtatct tatctataga gtatgaagaa ggattaagta gtgaagaaac
    30901 tatggaactt tccagaagac aaatagcaaa tatattagaa gataatatat ctgtgttcta
    30961 tggtggagta agtggacttg tatctataga taaattttta aaagaagata aagttattta
    31021 tgacaatagt tttgttactg ttgaaagaga cttatttgat ataaaatcac aaaaacatat
    31081 aacagaaatt tcatctggtg attttatttg tatgacatat aaagggcctt acaaagaaaa
    31141 ttataccgct tttaagaaac tggttgatta tgttgaatat aaaagaatac ctattgaaaa
    31201 ttatatatat gaaataccta taatagaccc tctgtctaca aacaacgaag aggaacttct
    31261 aacagaaatt caaatacaag ttaaaaagag agaaattgac ttaagatgtc tagtgtagta
    31321 atctagttta cttacacatc ttaatatagt tgtctattat caacatatga tttttctaga
    31381 tagtgattcc taacagtgag attttcaaaa aataggagga aatatggcta atgctaattc
    31441 cctcctattt ttaattaagc catatcattt taattaagcc atgtcatcac gaagtgcatc
    31501 aataatattt tcttttttta tcttattaat agtatacaac attgtaataa atactataaa
    31561 taaaacacta aatatactaa ttccaatact aaaccatgga atcacaaaat caatatcatc
    31621 tgtaaccatt actttatgaa ttagccatga agaaattact gctataggaa gtccaaagaa
    31681 caatgctctc atgccataaa aggcacactc aaaattcatc atcttttgga aatcatgctc
    31741 agacattcct acagagcgaa gcatggcaag ttctctacga cgtaacttaa tattagttga
    31801 aattgtatta aacacattgg caatcgaaat cagagaaatc ataattatga aagtataagc
    31861 aaaaacattg gcaataaaaa tgtaattacg gttctcatcc atcattccat acatattgta
    31921 cagattgtac tcattcgtaa ctccctcact ctcaataatt tgctccattt ctgcaactga
    31981 ctgagtagga tttttcgatt gaaagcttaa actttcaatt cctgtagaaa caccaggaat
    32041 ctcaaactta tctttggctg aataaggagc caatactctg aagcttgctt tcttcacatc
    32101 tgaacttctg attcctggag gagaatcagg tggcactact ttgacaaatg aaatattcac
    32161 attttgtctc tcaggtatct ccaacttgcc attagtttca ggagtgaggc taacattcat
    32221 agaagaactg ttgaaaatat caataatatt attatccttt gttaccatag aaacagcaat
    32281 cagttttgca ttttgtccag tatattcttc tgctggtaat ccaagacttt taataatatt
    32341 cagataagtt ctatcatcaa gaaattgcat atctactggt aattcaagca tttcactcat
    32401 agaatgtgaa ccctcatagt tcaaataatc gtctgtaagc tcacttactt tggcaacaca
    32461 tgaataggtc ataagtttct gatacaaacc ttcgtaaaca ccatttgcag tttttagctt
    32521 atcgtaaagc ttcaacattt cgttgtcttt cataccttgt gtagaaaaaa taatatcctg
    32581 gtcagtaacc tctgacctct gatttgacat ctgttttagg tctgctacta aagcacttgt
    32641 agatataaat agaactatgc ttaaaacaag cgacaataca atacttcgat aacgtttctt
    32701 gtttctttta aagtttttca tagcaagaac tccctcaaga ccataaactc gctgtgttag
    32761 ttttgatgtc ttcacagatt tagattcaat ttttacctca tttgtctgac gaatacactc
    32821 catcactggt gtgttggcag cctttcttgc tggtatgtaa gcagaaatta agattgtaac
    32881 catacttacc actgctgcaa cgatgattgc agggatagac aatgttaatg tcaacggaac
    32941 gtttacatag agaatatttg caaagttttt agctatgaca gaaatcacaa gtccaatact
    33001 gactataccg attgcaacac caattggtat accaatcgca ccaatgcaaa ttccttcaaa
    33061 tagcaccgaa tttcgtaact gttttgctgt agctccaaca gatgaaagta ttccaaattg
    33121 atgtgttcgc tcgttcaatg acatgttaaa tgaattatat attagaaaaa ttgagcctag
    33181 catgattatg gcaagcacaa tgccaccaac cgagtacaaa aacatattga acaaattgtt
    33241 atcagaaaca cctatgaagc gcaacacatt gtcattgaaa atggaagcat ggtctttagt
    33301 gctacttatg taagagcgaa tctgatgtgg atttttcaat gtgacaaaaa ggctaagact
    33361 gtcagtcttg acttgtttat cttctttggt tatcaaggta tatcctggtg cagaagattc
    33421 ttcaaatacg ggctttctac agatacccac aactgtataa gttttcttat cctgtggcac
    33481 aaaaacttca ctcccagcag tgtatgggtc actctgacca agcttttcat tttcactcat
    33541 tcgtttccct acatccaaag aaatagtatc acctactgca aatttgacac caccatctgt
    33601 cgcaacttta cttgaaacaa gaatctctct actattttca ggtaatcttc cagaaattaa
    33661 agttataggc aaagtatcaa aagcttcttt gctaaatcca gcaataaaaa gatatggttt
    33721 atctggattt ctgttacctt caagtgttgc atagccaata ttttcaaatg ttgcagtatt
    33781 tgcaacttca tcattgactc tttgttcctg tacaaaagaa gaatccacat ccaaaaactg
    33841 gacatgccaa tcaccatatt ttataatagc tccatttgtc atatagttca tcaaagaaac
    33901 tccaaaggta gtaactgctg taatcatagc agctgacaga acaactccta taattgttac
    33961 aagagttcga gtgcgattct ttttcaatcc ttgcagagca actttgttaa aaatgttcat
    34021 taacgattca ccttcctctc atcacgcact acttttccat ctgaaataca gataattcta
    34081 tctgcctgta aagcaatgtt ttcatcatgt gtgacaataa tgagagtttg gtgatattta
    34141 ctatggctct ctttcagtaa ctggataatc tcttgtccat ttttactgtc taagctacct
    34201 gtaggctcat cagcaagcat aactgctggt gcattcatca atgcacgacc aatggcaaca
    34261 cgttgctgtt ggccaccaga aagttgattt ggtaaatgtg tttttcgttc ttttaaacca
    34321 agcaattcta acaagtcatt taaccgttct tgattgacct tacgcttatc cataagtata
    34381 ggcaatgtga tattttctac tacatttaat gtgggtatca gattgtgaaa ctgataaatc
    34441 aatccaactt gtcgcctacg aaaaatagca agtttttcat tgctttggcc atatacatct
    34501 tgcccctcca gatatatctt tccacttgtt ggtacgtcta ctcctgcaat ggaatgtagt
    34561 agtgtagatt taccagaacc agaagaacca atgattgcag taaactctcc tttttcaata
    34621 gtaagtgaga catggtcaag tgcagtaacc ttattttcat tcttaccata aaccttacat
    34681 aaatcttcaa tctttaaaaa cgccattata taagtctcct ttcatatttt ataaatatat
    34741 cataggactt tcaacttaca tttaagtgac atttaaatga gagattcgtc actttggaaa
    34801 acgaataaca aatattgcac caccttgtgg gtgattttgt gcagtaattg ttcctccttg
    34861 tctcataata atcgtcttac aaagtgccaa tcctattcca taaccggctg tgcttgaatt
    34921 tttcccacga taaaatctgt taaatagaca tggtaaatct tcttttttaa agcctgctcc
    34981 gttgtcatga atagtaagtt gagtaaacaa aaagttgtcc tcacaaatga tatcaatttt
    35041 tccattatca cccacactct ccatgcagtt tttaaatata ttttgaattg cttctgaaag
    35101 ccaatttaaa tcacccaaaa tccttactcc ttttggtata tcaatatgta aagtgatatt
    35161 gtgcagttcc atgggaatca aaagttgatg aagtgcagaa ctaatcaaat tattcacatc
    35221 aatttgttct ttttgaaaga ctacaatacc tgcatctaaa cgtgataatt ttaaaaggga
    35281 agtaatcagc cagtccattc gtataagtaa ttcctctgtt tctcgtatca actcttttct
    35341 ctcatcttca tcagaagtat tctctaacag tgacaaaata agagttactg atgtaagagg
    35401 agtgcgaagc tggtgggcta tgtcagctag tgagtcagca aggtgttctt tttctttttt
    35461 caatgcgtaa ttttgctctc taatacgtaa cgtcatttta gttatttcac tttgcagaat
    35521 agaaagttca ccctcatctg attcagcaat atacagatgg ttagcattat gaagcacaag
    35581 attaatttgt tctgaaatct gtgcaatact tttgtatcga tttttagtaa acacaaaaaa
    35641 tgctattcca aaggtagtgg cagaaacaat agaaagtatt ccagtcataa tactgattgc
    35701 aaatcccagg gctacagtga gaatagtaat taataagaat aaaatagcaa attttcgaaa
    35761 ctctctattt cgaaacataa cttcccccca atctataccc tgtcccacga acagtcaaaa
    35821 ttatttgtgg acttgaaggg tcatcttcta tcttctctcg caagcgtttg atgtacacag
    35881 tcaatgtgtt gtcattaaca aactcacctg ccgcatccca caattcatca agtaatctta
    35941 ccctcgtaat aatactttta ggattgctaa taaacaccaa taacaaacgg tattctaaag
    36001 ctgaaagaaa aacctcattg ccattctttt tcacaacacc ggttgccgta tctacataaa
    36061 gcccacaaat ttcaaaagtt gacccaaaac gcccactttt tcgtagtgct gttctaattc
    36121 gcgcaatcag ttcacgtgga cgaaaaggtt tagtaatata atcatctgca cccatattca
    36181 gtccagtaac aacacttgat tcatcaccgg aagctgtcaa aaagataaca ggaatgtctt
    36241 gcttttcttt gatttctgtg caaatcgtaa acccatttcc atcaggtaaa gaaatatcaa
    36301 taagtgccaa atcaaattta ttcttagcaa tctctacaag tgcttcactt cttgtggata
    36361 catgggttac tataaatcct tctgaattaa gcaaaagaat aagatttttg gcaattgctt
    36421 tatcatcctc aactaaaaat atccgtttca tttactttca tcctccttta ttttattagt
    36481 tttatatatt ccagcagagc aatagtacac tactatttta cttatcatta cacaattttc
    36541 agtagtttct tttgttctta tataatccat gcataatacc tccattgatt tattatattt
    36601 cttataacat aaatacacaa gataagacaa aaaacataat gtaagtgcaa gttttttaac
    36661 tcactaactt ataaacatac actcctacta acactacttt cttgatgaca catcttacaa
    36721 gcttatattc atacatcaat gaaaaattaa atttatccat ttattaaaat aaaaggcaat
    36781 agcttctata gctaatgccc tttatcttaa aatgatttaa atactataca atttttataa
    36841 atggctataa ataaactcgt atagaatata aaatttatct acagtctttt gttatacaaa
    36901 atttataacc tcttatagaa caaatttacc actttgcaaa cttatcactt ttactcagct
    36961 atattataaa cttttaattt atctttgttt aaatgtttct tcttaacttc tactaaagct
    37021 tttagcgtat ccaaagatgt cattatttca gtagaaaatt caatggctgt tcttctcatc
    37081 ttaaatccat ctcttgtaga gtcatttcct ttagttggtg tatttattac tatatcaact
    37141 tgtttatttc ttatagcatc taatatgttt ggtctaggct cttcaattct atttactata
    37201 tcagcctcta ttccattttc tcttaaactc ttcgctgttc cttctgtagc aacaaaagta
    37261 tatcctaatt ctttcatatc ttttgctatc tctataaact catctttatc atgattattt
    37321 acagtagcaa gtactactcc tctttcatca gacatatgtc tacctgctgc caagaaccct
    37381 ttatataagg cttcttctaa attttctcct acacctagaa cttctcctgt agacttcatt
    37441 tcaggtccta gacttacttc aactttagat aatttagaca ttgagaatac tggtactttt
    37501 actgatacta attttggctc tttgtaaact cctgtactat atcctaaatc ctttaattta
    37561 gctcctaaca tacacttagt agccaagtca actattggta ctccacttac tttacttata
    37621 tatggaactg ttctactagc tctagggtta acctcaatta tatataattc attttgaaat
    37681 tctataaatt gtatattaac cataccaagc acattaaggt ctaaagctat ttttttagtg
    37741 tattctacta ttttttcttt tatttcatca gatatatttt gacttggata cattgttgta
    37801 ctatctccag agtgaactcc agctctttct aaatgctcca ttataccagg tatcaatata
    37861 tcttctttat cacatatagc atctacttct atttctctac cagttagata tttatctata
    37921 agtactggat ttttatggtc tctatcaaat gcatcatcca aatactgaat tagtttttct
    37981 tcgttataag ttatttccat accttgacca ccaagtacat aagatggtct aactaatact
    38041 ggataaccta actccttagc aatttcaaca ccttcattag ttgtccatac accttttcct
    38101 tttggtctat ttatatctag tctctctagt aaatcatcaa atttttctct atcttctgct
    38161 gcatctatat ctctaaagtc tgttcccagt ataggtatat ttttttcatg taaaaactta
    38221 gccaatttta tagctgtttg tccaccaaac tgtagtatta caccttctgg tttttctttt
    38281 tctattatat ttaaaacttc ttcttctgtt aatggttcaa aatacaactt atcagatgta
    38341 tcaaaatccg tacttacagt ttcagggtta ttgtttacaa ttatagtttc tattcccatt
    38401 tttcttaaag attttacaca gtgaactgaa caatagtcaa attctattcc ttgacctatt
    38461 cttattggac cagaacccaa tactacaact tttctcttat cactaactac tacctcatca
    38521 tattgttcat aagttgaata gtaataaggt gatagagctt caaattctcc tccacatgta
    38581 tcaaccattt tataaactgg ttgtatatta tataaacttc tcaattcata taatttttct
    38641 gggcttatct tcattaagtc agatatacct ttatcagaaa atcccttttt ctttaattca
    38701 tgtaaatatt ctttatctaa gtcttctatt tttagaactt ttaacttttc ttcttgttct
    38761 actatccatt taaatttatt tataaaccac ttatcaacac cagttatttc tgatatcatt
    38821 tctactttat agcctcttct tatcatttca gctaagtcaa atagtctctc atcatcaggt
    38881 actactactc tagcctttaa ttcttctaat gttctacctt ctgatggagc atgaaccaat
    38941 gaatattttc ctgtttcaag tgatcttata cctttaagaa tagcagcctc aaagttactt
    39001 cctatactca tgatttcacc agttgccatc atcttagttc ctaattttct attggcatgt
    39061 ctaaatttat caaatggcca ctttggtatt tttactacca cataatctaa tgttggctca
    39121 aaacaagcat aagttttttt agttactgca ttttctatct catccaaagt ataacctaaa
    39181 gctatcttag ctgctacttt tgctattggg tatcctgtag cttttgatgc tagggctgat
    39241 gacctactaa ctcttggatt tatttctatt atcgcatatt ctaaactatg tgggtttaaa
    39301 gctatttgaa cgttacatcc accttgaacc tctattgcat ttattatgtc tattgatgcc
    39361 tttctaagta gttgatactc ttcatcactt agagtttgac ttggagcaac aactatactg
    39421 tctcccgtat gaactccaac tgggtctaca ttttccatat tacatacagt tatacagttt
    39481 ccatttccat ccctcattac ttcgtattct atttctttcc aaccttttat actcttttca
    39541 agaagaactt gtccaacagg acttagctgt agtccatgtg aaagtatttc tcttaattct
    39601 tcctcagtat cagctatacc tccaccagtt ccacctagcg tatatgctgg tcttacaact
    39661 actggatatc ctatcttatt ggcaaactca agacctgctt ctaaatttgt aactatatca
    39721 ctaactatta ctggttgatt tatttctttc attacttctc taaataaatc tctatcttcg
    39781 ccctttttta tagattctat agatgttcct ataactttta cattatattt atctaatata
    39841 ccagcatcat gtaattctac agctaagttt aatcctgtct gaccacccat acctgcaagt
    39901 aaactatctg gtttttcttt ttctattatt ttttctataa attctattgt taatggttct
    39961 atatatattt tatctgcaat ttctttatca gtcattatag tagctgggtt actatttact
    40021 aatacaactt caattccctc ttcttttaat gcttggcagg cctgtgttcc tgaatagtca
    40081 aactctgcag cttgacctat tattattggc cctgacccta atactaaagt tttctttata
    40141 ctatctaatt taggcataac tctttctcct tatctaaaca attttcacag ttcttatctt
    40201 catcatctat acaatcaact ttaattactt tattttatct taaattcaaa tttactcatc
    40261 aatacatcta tttaatacat ctatgttaat taaaccaaac tttttgattt aagttattct
    40321 tgttttttag ttagctattc taatgttatt tattttacta attctaaaaa tttatcaaaa
    40381 atatagtcat tatcttttgg tcctgggcaa gcttcaggat ggtattgaac actgtataca
    40441 tctagtttct catgtctcat tccttcaaca gtattatcat ttaaatttat atgtgtcact
    40501 ttcatttgtt caggaacttc tgaaacataa taaccatgat tttgagaagt tataaatact
    40561 tttccttctt ctaaatcttt aactggatga tttccacctc tatgcccaaa tttaagttta
    40621 gcagtttttc ctccaagagc taaagctaaa agttgatgtc ctaagcatat tccaactata
    40681 ggttttttac caataagagc ttttatattt tctataacat cttctaggtc ttctgggtct
    40741 ccaggtccat ttgacaagaa tattaagtca gggtttatac tcaatacatc ttctggagat
    40801 gttgtagctg gaaatattgt tatatcacat ccacgagcta taaatgatct taatatattt
    40861 ctttttactc caaaatccat aacagccact tttggaccat ttccctttat atgctctact
    40921 tcttttcttg taacagttct aactgcttct gtatttgaaa acttatccaa tttatgttta
    40981 acatcttcta atttactgtc ttctaatgta attatacctt tcatggttcc attatttcta
    41041 agtatcttag tcaaagctct tgtatctatt ccttcaagtc cgataacttt attttgcttt
    41101 aaatattggt ctatatcaat ttcacatcta aaattacttg gagaatcact tttctccctt
    41161 actatgaatc cctttacttg aactttttca gactctgctg atgataaatt tataccataa
    41221 tttcctacaa gaggataagt catagtaact atttgaccat agtaagaagg gtctgttaaa
    41281 acttcaccat atcctatcat tgaagtatta aatactactt ctcctacact ttcttctaaa
    41341 tatccaaatg cctttcctat aaaaactgtt ccatcttcta atattaacct tgctttcata
    41401 ctacagtacc tcctataatt ctctttagac aaactaaaga acattaacta aatataagct
    41461 tttaaatatc tatatctatt tttcactttt acattctagt tttatactta tttacattta
    41521 ttttttatct ttttctatta tactacaaat ttcttaaaaa aaagaagtta tctcaaaagt
    41581 aaaaactcct agaaaaaata acctcttttt tttatttaat aattaaattc ttaaactata
    41641 caatcaactt aatttctatt cagctatatt gtaaactttt aactcatctt tatttaaatg
    41701 tttcttctta acttctacta aagcttttag tgtatccaaa gatgtcatta tttcagtaga
    41761 aaattcaata gctgttcttc ttatcttaaa tccatctctt gtagagtcat ttcctttagt
    41821 tggtgtattt attactatat caacttgttt atttcttata gcatctaata tgtttggtct
    41881 agattcttct actctattta ctatatcagc ctctattcca ttttctctta agctattagc
    41941 tgttccttct gtagcaacaa aagtatatcc taattctttc atatcttttg ctatctctat
    42001 aaactcatct ttatcatgat tatttacagt agcaagtact actcctcttt catcagacat
    42061 atgtctacct gctgccaaga accctttata taaggcttct tctaaatttt ctcctacacc
    42121 taggacttct cctgtagact tcatttcagg tcctagactt acttcaactt tagataattt
    42181 agacattgag aatactggta cttttactga tactaatttt ggctctttgt aaactcctgt
    42241 accatatcct aaatccttta atttagctcc taacatacac ttagtagcca agtcaactat
    42301 tggtactcca cttactttac ttatatacgg aactgttcta ctagctctag ggttaacctc
    42361 aattatatat aattcatttt gaaattctat aaactgtata ttaaccatac caagcacatt
    42421 aaggtctaaa gctatttttt tagtgtattc tactatcttt tcttttattt catcagatat
    42481 attttgactt ggatacattg ttgtactatc tccagagtga actccagctc tttctaaatg
    42541 ttccattata ccaggtatca atatatcttc cttatcacat atagcatcta cttctatttc
    42601 tctaccagtt agatatttat ctataagtac tggattttta tggtctctat caaatgcatc
    42661 ttgtaggtat tgagataatt tttcttcgtt ataagttatt tccatacctt gaccaccaag
    42721 tacataagat ggtctaacta atactggata acctaactca ttagcaactt caataccttc
    42781 gttaagtgac catacaccct ttccttttgg tctatttata tctagtctct ctagtaaatc
    42841 atcaaatttt tctctatctt ctgctgcatc tatatcatca aaatcagttc ccagtatagg
    42901 tatatttttt tcatgtaaaa atttagccaa ttttatagct gtttgtccac caaactgtag
    42961 tattacacct tctggttttt ctttttctat tatacttaaa acttcttctt ctgttaatgg
    43021 ttcaaaatac agcttatctg atgtatcaaa gtctgtactt acagtttcag ggttattgtt
    43081 tatgattata gtttctatgt ccatttttct taaagatttt acacagtgaa ctgaacaata
    43141 gtcaaattct ataccttgac ctattcttat tggaccagaa cctaatacta tcaccttttt
    43201 cttatcacta acaactacct catcatattg ctcataagtt gaataatagt aaggagatat
    43261 agcatctatc tcacctgcac aagtatcaac cattttatat gctggtttga tattgtatag
    43321 acttctcaat tcatataatt tttctggact tatcttcatt aggtcagata tacctttatc
    43381 agagaatccc tttttcttta attcaagaag atagtcttta gttaaatctt caattttcat
    43441 aacttttaat ttttcttctt gctctactat ccatttaaat ttatttataa accatttatc
    43501 tatacctgta atttgttcta tcatttctac tttatagcct cttcttatca tttcagctaa
    43561 atcaaatagt ctctcatcat caggtactac aactcttttc tttaattcct caatgcttct
    43621 ctcctcagat ggtgtgtgaa ctaatgaata ttttcctgtt tcaagtgatc ttatcccttt
    43681 aagaatagca gcctcaaaat tacttcctat actcataatt tcaccagttg ccatcatctt
    43741 agttcctaat tttctatttg cttttttaaa tttatcaaaa ggccattttg gtatttttgc
    43801 caccacataa tctatagttg gttcaaaaca agcataagtt tttttagtta ctgcattttc
    43861 tatctcatct aaagtataac ctaaagctat ttttgatgaa actttagcta ttggatatcc
    43921 tgtagctttt gatgctaaag ctgatgacct actaactctt ggatttatct ctataactgc
    43981 atattcaaaa ctatgtggat taagtgcaaa ttgaacgtta caaccacctt gaacttctac
    44041 tgcatttaat atatctaaag atgctttttt aagcattgca cattctttgt tacttaaagt
    44101 ttgagttgga gcaacaacta tactgtctcc tgtatgaact ccgactgggt ctatattttc
    44161 catgttacat acaactatac aatttccctt tgaatctctt attacctcat attctatttc
    44221 tttccaacct tttatactct tttcaattaa tacttgtcca acaggactta attgtagacc
    44281 atgtgaaagt atttctctta attcttcctc attatcagct atacccccac cagttccacc
    44341 tagtgtgtat gctggtctta caactactgg ataaccaatt gtaagtgcat aatcaagacc
    44401 tgcttgtaaa tctgtaacta tatcactaac tattacaggc tgatttattt ctttcattac
    44461 ttctctaaat atatctctat cttcaccttt tttgatagat tctactgaag tacctattat
    44521 ttttactcca tatttatcta gtatgccttt ttcataaagt tcaactgcta ggtttagccc
    44581 tgtttgtcca cccatacctg caagtaaact gtctggtctt tctttttcta ttattttttc
    44641 tataaattct attgttaatg gttctatata tattttatct gccacttctt tatcagtcat
    44701 tatagtggct ggattactat ttattaatac aacttcaatc ccttcctctt tcaaagactg
    44761 gcaagcttgt gttcctgaat agtcaaactc tgcagcttga cctattatta ttggtcctga
    44821 ccctaatact aaagttttct ttatactatc taatttaggc ataaattttt ctccttatct
    44881 aaatggtttt tactatctgt aaataatact aaatctatat taatgctaag aatttattaa
    44941 atatacaatc taaatcttct tttgttgtgt attctggaat gtactgaaca ctatatattg
    45001 gtaattcctt atgtctcatt ccttctatag tattgtcatt taaatttatg tgagttactt
    45061 ctgtattttc tggcatttct gaaacattat atccatgatt ttgagaagtt ataaatacct
    45121 ttccagtttc taaacattta actgggtgat tacctcctct atgtccaaat acaagctttg
    45181 aagtctttcc tcctaatgcc aatgctaaaa tttgatgtcc taaacctatt cctgtcaatg
    45241 gctttttgcc tattaatttt tttatatttt caactatatc atttatatcc tctggatttc
    45301 ctgggccatt agataataag attaagtcag gatttatatt taaaatttct tctactgtag
    45361 tcattgctgg tactatagtt atatcacagt tacaagcctt aagagactct agtacactat
    45421 ttttaacacc aaagtctata actacaactt tagctccagt accttttata ttttcaattt
    45481 cttttcttgt aacatttttt actgaatctt tgttacaatg ctcttctaat ttagactgaa
    45541 catcttgtaa tgatacattt tctaaagtta taattcctct cttagttcca ttgtttctaa
    45601 taattttagt taatgctctt gtatctattc cttcaagtcc tattacctta ttttgcttta
    45661 gatatgtgtc tatatccatt tcacatctaa aattatttgg gttatcactt ttttctctta
    45721 caataagtcc ttttacttgc accttatttg attcaacatc ttctaaattt attccatagt
    45781 ttcctataag tggataagtc atagtaacta tttgtccata ataagttgca tctgtcaata
    45841 gttctccata cccagccatt gaagtattaa atacaacttc tccaatagct tcctttagat
    45901 atccaaatgc ttttccttca aatactgttc catcttctaa aattaatttc cccttcatgt
    45961 aagctacctc ccaaatattt tatctaagca ttttctattt ctcttacaat attaatagct
    46021 gattctcttg gattttctgc ttttgttata ggtcttccaa caactaaata atgagcacct
    46081 ttttttattg catctgatgg agttacaact cttttttggt ctccaacctc tgctgattta
    46141 ggtcttattc ctgggcaaac tgttataaaa tcagttccac atgcttctac tattttatct
    46201 acttcttgcg ctgaacaaac aaccccatct attcctgatt cttttgccag tttagctctc
    46261 tttatagcta actcttctgt tgtcatatta catcctatgt cctgtaaatc ttggttgctt
    46321 aatgaagtta aaactgttac tccaactact aatggctttt ctatatttaa tctttctgct
    46381 tcttccctag caattagtgc acattgtctc attccttcca tatctgatac atgtattgtc
    46441 attaaccaaa cattatctct cactgcagct ttcactgcac ttttcatagt atttggtata
    46501 tcatggaatt taaggtctaa aaatattttt ttaccttttt ctttaagata atctattgtt
    46561 ttaccttttg tggcaacgta ttgctctagc cctaccttaa atatgtctac actatcttct
    46621 aatctgtcta ttagttcttt agctttatca aattcgtcag tatcaattgc aactatcaat
    46681 ttttctttac catttatcat ttttacatct cctttttaat aaagcctaaa taatcataaa
    46741 aaaatcctca caccaaaaga ggcataagga ttttatctat acataactct attcattagc
    46801 tatgagatat ctttcccagt ctctctggac tagtttaaaa gactttatta tatttaaatt
    46861 tttattttat actcatcaaa aacctctaga agatttacta gaggttatat actaacatta
    46921 tctataaccc tttagtctct ctggactact ttaaggaatt tagctgtaat atttttcttt
    46981 atttatataa ctttatgtat ctataggata atttaaagtt ttatcttttt tataattaaa
    47041 ccactaattg ctttttatgt caataagtct ttgaattatt cttcatcttt atcaaacaat
    47101 tttttctcaa aatatgattc tgcattatat attgcagcaa ctggattatg cccagttact
    47161 ctatctttga caactaaagt tgttatagga gcttccatat atttcatggc taaagtatcg
    47221 tgaccaacac ataatccaag aattacatta aggtcaacct tagcttcatt taaaaataaa
    47281 gcttgtccta ttggattgca cattacctca tctgaacact ttgatattgt ttgagatgct
    47341 tctagtccaa ttgtactctt aggcattgcc ccatttttac atataacaga aaatacttca
    47401 aacccatgat gttcaaatat tttttgcact gtttgcattt ctctttttag tccaatacaa
    47461 aatgctatgc caatcttttt ataaccacac tttttagcaa actctataat ctcttttagt
    47521 ctagtatatt gacaataccc ctctgcttca actaatccag cattataagc tatttttcta
    47581 ttctcttctt cttcataaag ttgctttgct ttttgttgta gttcaatttc tctagttgga
    47641 catatcttca ttaatttatc catatttcca ttagaacagc ctctaagatt acattttcca
    47701 cacttataca tatccaatat ccccttccaa aattttattc atcttgcgat tcttcttttt
    47761 ctagagttac attttcttct tgggtttctt cttctggttt cacatgctcg actacagtta
    47821 taaaatatga ttttcctatt ttattcctta taggaagttt ttcatatgaa acatctattt
    47881 tattttttat acaagctata tcaaaatgtc ttaaggctac acctaagcta accttattca
    47941 tatcttcaca gtgtttctta ggtctctttt caaataaatg aagacctcgt tcatccttat
    48001 ggaaatacca cggttgagaa ttttttacag atggagctct tcttgtcaat tctaagatat
    48061 ctttccactt tctattccta tttatcttat ttatcatatc ttttactggc tttctatcag
    48121 gtctagcata tctcgtccta aacaactctt cattttttgc tggatatcca aatgctatta
    48181 ttatataagg attttctatt ttgttttcat catcttcttc tgtttttatt ccagctagat
    48241 aatctaaatc atcttcctca tcttcttcaa aattcttatt cccaatatct acaaattcca
    48301 agatatcttc tctctttaag tttccttcca accagcaagt agctattccc aatgttgtaa
    48361 ggcgcaaaac tacaccttct gtagcaaatc ctatattctg taaatagtcc tcacctttgt
    48421 ctgatgtaac tactatataa tgaggtgcct ttactttaca ttccttaccc atcaaaaaat
    48481 gtattatatg acctctatca acaacatgtg ctttaatatt taaatcttca tttaagtatt
    48541 ctaaattttt acaacttctt tttatttctt ccatcaatgg cttttttatc tttttactgg
    48601 aaaaatttct tacagatttt ctataaaaaa tggcttcata aagctccatt tatgccctcc
    48661 taactgaaat cttctgacgt ataaactcta taaatttata taaatacttt atatttttta
    48721 tagttttatt tcctttttcc tcctgcccta ttttgaaatt cataagaata tctactctag
    48781 tttaatatag cattcaaaag gcttaaattc taccttatca atgtctatac attagcataa
    48841 tttttttatt tgattttcta tgctaattta aataacaaca ctagctatta actttttaat
    48901 taagctttgc cagaaaaatt ttttttcatt tataaatatc tatctcatta ttatattata
    48961 agtttttttc ggtattcttg tatagctttt cactaaaaaa gtatttttat ttctacttta
    49021 atattattat caacaaaaaa catactgctt aaataagttt gttatcctca taatctgttt
    49081 taattaaaat atttttttta tttctcaatc tataaagtat aaatattttg aatatgaccc
    49141 aaaatctaag taaagttata atattttata agttgttcaa tattaaaaac ataagtaatg
    49201 ttataatact ttataagtta ttcaatatta aaaatatagg aggataaata tgaatttaaa
    49261 tagaaattta gaaaaatacg ctgaattagc aataaaagtt ggagttaaca tacagccagg
    49321 tcaaattcta cttataaagt caccaataga atgtgctgat tttgcaagaa atgcacttaa
    49381 agaagcatat aaatgtggtg ctaaaaatgt ttatatagag tggtctgatg aagaaagtac
    49441 tcttattaaa tacttatatg ctccagatga agcatttcat gagttcccca aatggacagc
    49501 agaacaatat gtagatatag caaaagaagg tggggcattt ttatcagtct atgcccaaaa
    49561 tccagattta ttaaaagatg ttgaccctga aagagttgca aattttcaga aggcatctgg
    49621 aaaagcttta aaagaatggc gttcttacac tctaactgat aaatgtaaat ggagtatagt
    49681 ctctgtgcca acaaaagatt gggcaaaaaa agtgtttcca aatttatcag aagataaagc
    49741 aatagaaaaa ctgtgggatg ctatatttaa atgttcaaga gtagatggtc aggaccctat
    49801 aaaagcatgg gaagaacata atgaaaatct taaatctaaa atggactttc taaataaaaa
    49861 taactttaaa actttaaaat ataaatcctc aaaaactgat ttgactctag acttgccaaa
    49921 gggtcatgtt tggctaagtg gagcatccaa agaccctaat ggaataagtt ttaatccgaa
    49981 tattccaact gaagagattt ttggaatgcc acataagttt aaagtaaatg gaactgttta
    50041 tagtacaaaa cctcttgttt atggtggaaa cataattgac aatttcttct taacatttaa
    50101 agatggtaaa ataatagatt tctctgctga aaagggactc gatacactag aaaaacttat
    50161 tgaaacggat gaaggctctc attatttagg agaagtcgct cttgttccat acaactcacc
    50221 aatatccaat acggatataa ttttttataa tactctatat gatgaaaatg cttcttgcca
    50281 ctttgcaatt ggttctgctt ataagacttg tctggaaggt ggaaataatt taaaagatga
    50341 agaattagat gaacatggtg taaatgacag tttaacacat gtagatttta tgattggttc
    50401 tgctgatatg gatattattg gtgagactta tgatggaaag caaatacaga tttttaaaaa
    50461 tggtaattgg gctttttaac atatgatttt aactaaaaag ggctgatgga agttatacca
    50521 gacttcccag ccctttttaa tgttgatgat aaatattttt tatattaatt aatctcatta
    50581 ttatagatta attcctattg ttttaaacat aagtatctaa aacttatatt tatattatat
    50641 ataaaatatc ctatttagta aaacctttat tttaatttat atgctaaaaa tttaactttg
    50701 ctatttcaac agcagacttt gcatcctttg aataataatc agcacccatt tcttcagcgt
    50761 attcttctgt caaaactgca cctcctacaa atacctttgc atttatctca ttatctctca
    50821 gtgcctgaat tgtatctttc atactttgaa cagtcgtagt cataagtgca cttaatccta
    50881 ctaattttat atttctcttt ttagcaactt ccactacttc ttcaataggg acatctttac
    50941 ctaaatctat aacttcatat ccataatttt ctagcattat ttttactata tttttcccaa
    51001 tatcatggat atcacctttt actgtagcaa ctattatttt tcctttggat acattattgc
    51061 tacttttact taataaagtt tcctttattg tatttaatga aacttttacc gtttctgctg
    51121 attgaatcaa ttgtggtaaa aatatatctc cactatcata tctttttcct actttatcaa
    51181 gagcaggaat taaaatctca tctaatatat aattttcatc cttctctttt aaaagattca
    51241 gtgttacatt ttttgcttca tcttttaatc ctctttcaac taaaatatcc aagggcaaat
    51301 ctttatcaat ctttgtagat gaatccgatt tttttgaatt atttatattg ctatattgat
    51361 ttatatagtt tatacatcct ttatctgtgt tatttaatat tttaaaagaa ttgatagctt
    51421 ccatcatact atattcattt ggatttataa ttgctaaatc aagccctgcc cctaaagcta
    51481 atgttagaaa agaagcatta agtgctttcc tatttggaag accaaatgaa atatttgaaa
    51541 cacctaatat agtttttact cctagtgtct ttaccattgt tatagctttt atagtttcta
    51601 ttgcttcttc ttgttgtgct gaaacagtta atgataaaca gtctataaat atatcttttg
    51661 gttttatccc ataagaaact gctctattaa ctatcctttt tgctatttca aatctttctt
    51721 cagccttttt aggtatcccc ttttcatcaa gtgtaagtcc aaccacacat gaaccatact
    51781 ttttaactat tggtaatata ctttctaaag actcctcttt gccatttaca gagtttacta
    51841 ttgttctacc attataatat ctaagtcctt gctctaaggc ctctacattg gaagaatcaa
    51901 cttgtaaagg tgtatctact actgcttgaa tctctcttat taattttggc attagttttt
    51961 tttcatcaat ctctggaaga ccaacattta ctccaagtat ttgtgctcca gcatttactt
    52021 gttctaaacc taaatttata gcataatcaa cattttcatt ttttaatgct tcttgtagag
    52081 attttctacc tgtgggattc aatctttctc caacaactgt aggcgattgt acttccacaa
    52141 attttgatgg tgaacagact acacatttat caattttctc gatacatccc tttgtaacag
    52201 aatttatatt ctcagatatt tcttttataa aacttggatt cgtaccacaa catccaccta
    52261 ttatagtagc accaacttca acgaactttt taaccccttc aaaaaattct tttgcatcaa
    52321 catcatatat agcctctcca tcaactatat ttggaagacc tgcatttgct tgaaccataa
    52381 cagggactgt agctcttgat gctatttttt caactattgg taaaagttgt ttaggtccta
    52441 atgaacaatt aactcctatt gcatctacac ctagaccttc tatagtagcc accatacatt
    52501 ctggcataca tccagtaaaa cttcttccac cttcatcaaa tgtcatagta cagaaaatag
    52561 gtaaatcaga gttttctttt gctgctaata cagctacttt agcttcatat aaatccatca
    52621 tagtctctat tactattaca tcaactccag atttaacgcc ttgtagtact tgtcttttaa
    52681 atatttcata tgctttatca aaacttaaag tacccatagg ctctagcatt tctcctatag
    52741 gaccaatatc taaagctaca tatcttggtt tagtattatc tacattttct atagcttttc
    52801 tagccaccaa aacagcattg tcaatcactt cttctacagt atacttacta tctaatttta
    52861 gttcattaca tccaaaagta tttgtaagaa ttacattcga acctgcctct aagtatgctg
    52921 tatgtatttc tataagttta tctggatttt gaagaccaaa tacttctgga ttttcaccta
    52981 actttaaccc tttttgttga agcattgttc ccattgcacc atcaaatatt aatatattat
    53041 ttttcagata ttgtcttatt tccacaagag ttcgctcctt ttctatatgt acagtttcta
    53101 tagtttttac aattttcaca cgacttttct ttcttagatt tatttattct tgtattagaa
    53161 atacctataa tagccactac tgactttctc ggtatcataa ttccattaga agtaattgtt
    53221 agacctattt gtttttgagc attcaaaacg tttaatatat ctatattttt ttctattggt
    53281 aaatctccat atcctgggct atatcgcata gttataaatt tatcttgctt taaaaaaacc
    53341 ttttctaaat tattttgaac aatgtcacac acttcttcta ttgctgttgt tccacatgaa
    53401 tcaattatta gtccttttgt taaatttgaa taagagtgtc gtcttatttc tttttctata
    53461 tctatcccta tagtagctgc cataattaca cactcattac attcttttaa aagttcatat
    53521 acatctttac tctctaatgt taaatttgtt ccctctaatt ctacaacatt atctttattt
    53581 attttaatag gataaatcct agataaatat ctaggattta ttttattttt agttatagct
    53641 acacattcat caatagtata tttaaggtct ttatctatct cttgacctct gtattgtaaa
    53701 tatcttaaaa cttcactttg atttatgctt atatcttctc ttccaattaa attattctcc
    53761 atatatattt aaagaaaatc ctttatctaa aacatctttt gcatattcct ttgccccaaa
    53821 taaagataag tctctgtagt ttccacattc tatagctgta gctgctggca ttttatctga
    53881 ttcaagaact ttttttaatg cttcttctaa accaatctta actgttttgg catctacatc
    53941 tccccatagt attaaataaa atcctgttct acatcccatt ggagataagt ctattacacc
    54001 atctaatgta tctcttaaat aagtagctaa aagatgctct aaaccgtgca tagcagcagt
    54061 tccaaaactt tctacatttg gctgtaaaaa tctcaagtca aatttagtta ctttatctcc
    54121 ctttactcca tcaagtacac tacactttct tacaaaagga gcttttactt ttgtatggtc
    54181 tagcttaaaa ctttctactt tttccattat ttaatcctcc attatacttt aaaatttgtt
    54241 acattaattc taaaaaaaac tcttcctatc tattattgat aagaagagta tattatttca
    54301 agtcatctca tcgttgttag caggaccacc tgataaaagg ttggtatagg atcactgagc
    54361 taactctctc ccctaactct tgataagtat cttattaaac tgacttaaat tatatattac
    54421 ttttttattt ttgtaaacac tttattgtta taatatttat atcacataat cgtactttta
    54481 ttttataact aagctgattg tattattggc agttgtactt caaacacagt ttgatattta
    54541 tcgcttgaaa cagtaatttc tccatcatgt aaatttacaa tattttttgt aatcgcaaga
    54601 cccaatccag aacctccaac atttctattt ctcgattttt caactctata aaatctatca
    54661 aatatatttg gtaaatctaa cactggaatt ggttccccat aatttatcac ttttacaacc
    54721 gccatatctt cctttttctc tgtgactata tctacataat gcccatcttt tccatatttc
    54781 acagcattag ttataagatt ttcaaatgct cttaccaatt tatttggatc agcttttaca
    54841 attaattttt cttcattaaa attaattcta ctaaccataa attcttgttt aaaataaatt
    54901 tcaaattgag atactacttg acttaataac tctactaaat ttatttctat tttgtttaat
    54961 tttattgtat tattttgcat tttagtcaat tcaaacaaat catttataag aacatttaaa
    55021 tttttcgatt tttcatatgc aatatcaaca taatacatca tctgaacttc atctttatac
    55081 ttaccttctt ctatcactcc taaataaccc attatggatg tcaaaggtgt tcttaagtca
    55141 tgtgacacat ttgttattaa atctgttttt gtctgctgag cttgtctctc ttcaatagtt
    55201 atatttctaa gttgatggac tatattattg attttatgtg ctagttcatc aatatcatcc
    55261 ttttctttat cctttaatat atctaagtca tactcaatat ctatactttt ttctaagtta
    55321 ccttcatcca ttaaatttac agcactttta atgatttcta atttttgatt ttttctatta
    55381 gtctttctta taaaatctac aatttgctta tttctcttgt acgatatcat ggaataaatt
    55441 gctaatgatg tgattgtaaa taaaaatgga taaaataaat cataccctat aagacttctg
    55501 aaatctcttg cttgatatac aagttgatta actacagaca tatcactatt gacatataat
    55561 gattttatta tatacatact tgttaaaata agcattgaag ttaaagcaca gcttattata
    55621 agatctaata tgggtcgaaa catatgattt aataaacttt tatttttcaa ttttatatcc
    55681 tactccccat acagtatgaa ttattttttc tccatctgta tatttttcaa ttttatccct
    55741 tattctgctc atatgaacca ttacagtatt attagattgg taatatttct ctttccatac
    55801 cttttcaaat atttcttctg tactatatac tctgccttta ttatttgcta ataaatataa
    55861 tatatcaaat tctcttgatg tcaaaattat ttcatttcca gccactgtta cactatgttt
    55921 ttccttatct ataattacta ctccaacctt tatgacatct ttatcttcat tattagcacc
    55981 actaaaataa tatgctcttc taatcagcga cttcactctc acagtaagtt caagtgggtt
    56041 aaatggtttt gtcaaatagt catctgcacc agtcattatc ccttgtattt tatccatgtc
    56101 ttctgatttt gcacttaaca taagtattgg tatattcaaa ctttctctaa cttttctaca
    56161 aacttctatc ccatccattt taggcatcat tatatccaat atcattaaat gaatattttc
    56221 cttttttaaa atatctagag cctcttttcc atcttcagct ttaattacat tatatccact
    56281 atttaaaaga tatatctcta taaggtctct tatttccttt tcatcatcca caacaagaac
    56341 tgtattattc atttttacac atcctaactt aatctttgta tatagcttta ttcatataaa
    56401 attatactat attttagtta gtgtaatcta taaatttatt aatttctaaa tttccaatat
    56461 aatacaaatt atttacacat ttatattatt tattttgtaa atattcttct aaagttaatc
    56521 cttttgaata aatttcctcg gcagcatcct taccaacata tctaatatgc catggttcat
    56581 atgctgtacc tgttatatct tctttacctt caggatatct tattataaat ccaaacttgt
    56641 gagcattttc tgccaaccat ttagcttctt ttgtacttcc aacaaaccat ctttctggat
    56701 ttgttaaatc aatacaaagt ccagtttggt gctcactgta accaggcttt gctacatatg
    56761 catctgcctt ttctcgtccc tgagatttta cccttcttgt ataagtatcc agttgagtat
    56821 cataagatct gtatgctgaa gaccctaaaa actgtattcc ttctgaatta gcttgcttaa
    56881 ctaaatcttc aactgccttt gcaggttctc ctgccatttg tttttcttcc tctgttgctt
    56941 cttcaacaaa aggtatgttt accttagtaa tattttcagg agtatagttt ttgctaattc
    57001 catttgtctt gtttaccaat aatatatttg atatactatt tgagtgattt ttattttgag
    57061 aatttgcctc aacatcttgt tctgaatcat gttgagcagc tactattgga tctttatctt
    57121 tcttaagtaa tctatcttta gatataaata cacttataaa tactactaaa ataatggctc
    57181 ctattaattt aaattttttc ataattaaat cttctccttt ttgttatgtt tgctataatg
    57241 ttaattttag agtataagac ttaagtattt tataagtaaa tcttaaataa atcttaaatt
    57301 taatattttt aaaggatggt gataaaatgt ctatacaaaa acttctaagt aaagctcgta
    57361 aggctataca agattttgat atgatacaag aaaatgataa aattgcggtt ggactttctg
    57421 gtggaaaaga tagtttaact ttacttcata tacttaaaag ttatcaaaga ttttctccac
    57481 aaaactttga attgatagcc ataacattaa atactggagg tgttgataat tctccactag
    57541 ataaattgtg taaagaaata aatgttcctt tttatgaatt tcaaactgac ataaaagaaa
    57601 ttgtatttga tataagacaa gaaaagaatc cttgtgcatt atgtgctaat ttaagaagag
    57661 gtgctttgaa cgataatgct aaaaaacttg gatgtaataa agtagctctt ggtcatcata
    57721 aagatgatgc aattgagaca tttttaatgt ctatgtttta tgagggtaga gtaaattgtt
    57781 tttccccaaa gacataccta gacagacagg atttaacagt tataagacct atggtttaca
    57841 tagaagagta tatgactaag aaaatttcaa aagattctaa ctatcctatt atcacaaatc
    57901 cctgccctgc aaatggtcat actaggagag agtacataaa aaatcttatt gctaatttaa
    57961 ataaagagat gcctgatttt aaaagaaatg tatttggtgc tttaaataat tctgagaaat
    58021 tgtttatatg ggataaagag aagataaaaa attttaaata ataattaaaa tttttaaata
    58081 aaaaagcaag attgtattaa ttgtaaataa tctttatata atctacacaa tcttactttt
    58141 ttatttatta tatgttatta tctttaatct atattttaat agttcttaat agtatttatt
    58201 ttgtctaata cattaattat aacttaaata ttttatatat taatttaatc tattaattca
    58261 ttcaatctac tggtttaatc catttttaca gtatatacat ctacatatta taaaaagcaa
    58321 aattatattt tctaaatatt ttatgttaga ttataatatt aaattctatt atctctggta
    58381 tattaaaaaa tctaaatggt aactttgtac ttccaagacc cgaactcaca tataaatgat
    58441 ttccatttat atcataaaac cctttagtat atttccttcc atatggagga gtaactaatg
    58501 ctcccttaat aggtaatctt atttgaccac catgactatg cccagataga actaaattca
    58561 ttgtatcttt actaagcata tctactaaat ctggttcatg tgctaacaat aaattaaaac
    58621 ttttattatc tatttgactc tccagatatt ttatattagg atttccattt aatatttcat
    58681 caacacctaa tatattaata tatttatcat cttttaattt tattttttta ttttcattta
    58741 ctaaaagatt gaagttggaa tttttcataa tgtgcctata atacctagga agtttataca
    58801 tataatcatg attgccaaat actgaaaatt ttcccaacct agcattcata cttgataaaa
    58861 tagttgtaat ttcatctaca cttggatttt tattggagta atcaattaaa tcaccagtaa
    58921 atactattat atctggattc aaagtgttaa tcttattagc tacttttttg agattcttag
    58981 ttgaataaaa actacctatt tgagtatctg aaatttgaac tacttttaca ctttcagatt
    59041 tactctcaat tgtatcattt tttatcaatg ctccattttc acttatatta tattttttca
    59101 caattaatag actcggctct atcgcaactg agtatataaa aatcaaaata aatattaaga
    59161 taaaaaattt taaaaaatac ttaatttttg agttcaaaat atctacctac ttatttattt
    59221 ttttaaacta tttgcattac agactcaact ttgttcattt ttctgtcatg catttttggc
    59281 ttatttgctg aaaaccattt atatgttgct gtaagacctt cttttagtaa cacgtttggt
    59341 atataaagcc catgttcaat aagcttattt atatcaagat taaagtctat atttctaaat
    59401 gggaaatacg ttctttctct aaactctact ttttccatat ctacatattt tattataggt
    59461 tctttgccaa taatttctcc acatgtatat ataaggtcat cccaagaaat taactgtgga
    59521 tttgtcacat tataggcctc tcttacatga ggatttttca ttatgctttc caataccttt
    59581 accaaatccc caatatatat aaattgatta ctaacttgtt ttccttttgg tactggtatc
    59641 ttttcatttt tttctatttt ttcaaagaaa taatactctc tatataaatt attattttca
    59701 ccatatatgt aagttggtct aataattata tatggtatag ggctatttat aataaaatct
    59761 tcagcctctt ttttatttaa cccatatttt ccccagtttt cattttcacc tttctcattt
    59821 tcttctttta tatttcttcc actatcttta tatactgctc ctgctgacaa tactatatac
    59881 ttttttaagt tatccatgct tataaaatca atcagattac ttacatcttc ttttgtatat
    59941 gctgtcatat catatatgta atcatatttt cttcctgtga taatgttttc catatctttt
    60001 cgaacttttc tatcacaaat tagatgttct ttaaaaccat tataatctat ttccttttta
    60061 ccatttgtaa gtatatcaat ttgataccca catttaatca agcgcttagc aagtgcagaa
    60121 cctatgaagt cgcttccacc cataattaaa atagatttca ttttaagtgc atcctcctct
    60181 tttttaaatg acttccttaa ctataatatc atatttttaa atatgcgaca ccattttgta
    60241 atatttttgt ctataaaaga tatttataac aaaatatctt ttatagactc tacattttcg
    60301 acaatataag taggttcact ttcactaatc tcttcaaaag aaccataccc atacaatact
    60361 ccaatagaat ctatacctat ttttttagct ccaattatgt catactttct atctccaacc
    60421 ataataactt tatctttatc ttttacatta cataggtcta gtacatattg tataacttca
    60481 tttttattca ctcttgtacc atcaagattg ctacctgcta tatatttaaa atatctatct
    60541 atatcaaaat atctaagtat agtttctgca aaaactgttg gcttagaagt tgctactaat
    60601 aatattttac catttttata gagcatttct aatatctctt tcatattctc ataaatttta
    60661 ttttcaaata tccctttatc agcaaaatat tctctatact tttcaacagc ttctttagct
    60721 tttttatctt caaatttata atactccttg aaagtatcat gtaatggtgg tcctataaat
    60781 tggtctaagt tttccaaatc ttcttttatg ccaaagctat ttaaagaata ctgaatagac
    60841 tttgttattc cttctttagg gtctgtaagt gttccatcta aatcgaataa tactatttca
    60901 taattttttt tcatatttca gtcctccata tttgtaaaaa gtaatatctt atatattaag
    60961 tttatctatt ttaaaaagct atagtaatag aaatttctaa tactatagct taagtaccaa
    61021 ttaaatctta tatatttatt ttaaaaataa atttaaacag ctctatttaa ctgttatagc
    61081 tgaaactgga catccttctt cggcttcttt acataaatct tgtaaatctt ctggtatttc
    61141 tccttcaatt gctactgaat gcccttcatc gctcatacta aaaacgtctg gacatgttcc
    61201 tatacatgct ccacaagcta cacatacatc cttatcaaca aatgctttca tactaaaata
    61261 cctcccctaa aattattatt ttttaattgt tgtttcctta gatatttatc caatatatac
    61321 caatttaaac atatatttat tattttatca ctattgttta gtttattata gtattttcgt
    61381 atccatgtct ataaacttca ctgcttttca tccatgattt tacagtatat tgcaatctta
    61441 attttttatt taaaacaagt tcattattat tgtagtcttt tataatatca ttacactcct
    61501 ccattgtaaa tattgtaaaa tcaccttctc caccaatctt tattctgcct ttatttccat
    61561 gtaaatcgaa aatctttgtt gggtattcag ttactttttc tatacacttt tctagggata
    61621 tcccaagttc cataatttta tttataacat ttaaaagaga atagtttacg tctttcatgt
    61681 tttttatatg catatcagta cttattaggt caggctctaa accttgcttt attgcttttt
    61741 taaaaacttt aaaatcaaat tggtccactc catgacatac atcaaacaat actcctctat
    61801 tctttgcatt tattactgat tttcttaatg tgccagattc tttaaggatt ccatttgtac
    61861 tatttccata tactggtgta accacatctc cttttcccaa aatattcatt acttcatcta
    61921 tatatgatgg atactctcct atatatacca ctaagggtaa atttattttt ttagcaactt
    61981 gctttgattt cttaattata tctataccac tttcattaga ttgaaattta ctcgctttta
    62041 cttttatacc ctttatcttt tctatatttt tttctacaat tgactcaacc ttgtcaaaat
    62101 ttataacatc taaagaagtt gattcattca atatatttag tccctcattt gtaacattta
    62161 aaaaagaata tacttctgtt ttacactcat ccatatactt ttttttaaaa tcatagtagt
    62221 ttgaaggacc agctgtacct gcatcaaata taactgtaga acctttttca attccaattg
    62281 aatcagaatc catacctgta ggtaattttc tcttataaca atgggtgtga acatctataa
    62341 atcctgggga aatatacata ttatcggcat ttattatctc gaactcttta tttgtaagta
    62401 atttttcttt tcttattttc tctttaaggt tcaatccaat agcatatatt ttcccatgta
    62461 aaaccaagat atctcttttt tcaaatttga taccatctgt tggagatatt attgtcccat
    62521 ttcttataag taaatttttc atttattcca catcctaatt acaatataat ttctctaata
    62581 gcttttctta cataaagaaa ataagcctaa aaataaaaat attttagact tattcactat
    62641 attatactat attaattata ttaaattaaa taaaatcttt aatttacttt aagaagcaat
    62701 taagtatttg ttgctcggct tcttcttcag taagacctaa tgtcatcatc tttagtattt
    62761 ggtctcctgc aatctttcca atagctgctt catgtactaa aagagcatct ggatgatttg
    62821 cagcaatttc aggtatagca ctaatttgag aatttcccat aattattgaa tcacattgaa
    62881 catgtgcaga acaaagggaa tccccaataa cacaaggatt aaacttttgc ttagaattat
    62941 cttgcccaac tgtacgagaa actacttgag cagaagagtt ttcaccctct aagataacct
    63001 tcatattaga ttctgcaact tgattaccat gagttaataa tttctcaaat acaactattt
    63061 tagctccttt acctaggttt gcatccattt ctcttttagt tgaatctaca cccttaattt
    63121 gaattgtttc catttcacaa tatgaatcct catccatatt gacaatagta actggattta
    63181 aaattctctt tccttctcca tcaccttcac cataatgttt ttctacatat tttaggcgag
    63241 ctcctttacg taagaaaaat ctatgtatac cattatgttc actatcatca caaccacagt
    63301 tatgtatacc acacccagca attataacaa catctgcatt ttctccaatt tcaaaatcat
    63361 tatataccat atcctgtaca ccagcctctg ttactattac tggtatatgt acattttctc
    63421 cttttgtatt tggctttact ataatatcta ttccaggttt atcagtttta ggaattatag
    63481 ttacattttc agttgaatgt ctctctactc cttgcccatt tttacgtata ttgtatgctc
    63541 ctaatggagt tccacgaagt tcagcaactt tttctaaaag atttaaatct attttgttca
    63601 tttaatttgc cttcctttct aattaattca tgtctttcat taattcacaa cttgaattaa
    63661 cttgacacat gatttcaggt aatatagcct cttttgttcc atggcttttt actgaaccat
    63721 cttgtagaac aattatttca tcagctaact ctaatattct ttcttggtga gaaattatga
    63781 ttatagtctg attagactct tcatgtattt tcttaaaact ttcattgagt tttccaaagc
    63841 tccaaaggtc tatccctgct tcaggttcat caaatataga aacctttaaa tctctagcaa
    63901 aaagagttgc tatctcaatt cttttcattt cccctccaga aagagagtta tcaacttcac
    63961 gatttaaata gtcttttgaa cacaatccaa catctgtaag gtattggcaa catacatcag
    64021 tagacaatgg ttttccatga gcaagtgtaa gtaaattttc aactgtcata ccttttattc
    64081 ttggtggttg ttgaaatgcg tatcctattc ctttttttgc tctttctgta atactaagat
    64141 ttgttatatc ttctccatct aaaattatct gaccactcgt agctttttca attcccataa
    64201 taagcttagc aattgtagat tttcctccac catttggacc tgtgataaca ataagttttc
    64261 ccctctcaaa tgaaaggcta acatcattta ttattcctag ttcctcattg ttagactcaa
    64321 cattaaagga aagatttttt atttcaagca taatacccct cttttctata aaatattaca
    64381 ttaatatcca ttcttttatt atatcagtaa tttttatata tcagcaactc taaggagata
    64441 aaatgtatat taaataataa aacaaagtta ttgaaaagta aaaaagatga gttttatgta
    64501 aactcatctc agaaatttag tatatcaact tatatgtatt taaaatttaa ccttctatat
    64561 actctaatat tattttttga ttatctttca acataatttc ttctttttta gattctattc
    64621 cattcttttt tatctttacc tcagctacaa aggcatcatt accttcaacc atttctaata
    64681 gttcatacgc ttttttacga cctattttag ttgctatatc ttttagtact gccattttct
    64741 taaacatttt atcacctcta ctcaaaattt acacttaatt tttaattata taattctaat
    64801 cctagactag tttataataa ttattgtctc taattatatc agatattgag taaatttaat
    64861 actttgtaaa attatttatc ctctctgacc aaataatcat ttccatcttg gtctttaaaa
    64921 gaaaacatcc ttccatatgg catctccatt aattccccaa cctcaacctc gttatttgcc
    64981 atttgttcat aagttccatt aatatctctt gtacttaaaa ttattgatgg atgagataca
    65041 tttatctctt tgttttgctt catcattaga tttttatcat acaacacaaa tgttgtaaat
    65101 tcatttttac ttggtgctac ttccacccat ttcatatttg gacccatttc cttttcataa
    65161 gttactacaa agttcaattt ttctgtccaa aataactttg catcctcttg attatttaca
    65221 tagagagtta tttttcctat tttatttatc ataacaatac ccacctttat tattaaataa
    65281 atacctaata ttttttatat ttaataatat acccatatat attattttct atagatatat
    65341 atttctaata tttatcgcca aattatgtaa ttctgctcaa tatataattt ataatatcca
    65401 tactattata gcctttattt atgtaattta atcaccttat atatcatact tataattatg
    65461 ataataacta cataaaaaat cacttctaaa tagagttatc catctaaaag tgatttcata
    65521 tattctatgc aactttgtgt tttagccact ttgttcctct taatcttaaa caatataaag
    65581 cccctctaac aagccaatca gtatacatac ctatccaaat tcctaacact ccaaattcta
    65641 atacaacccc caatacgtaa cctgtaaaaa ttctaaaaat ccacatacct attactgcag
    65701 tcatcattgt atatctagta tcaccggctc cctttaaccc tgctgataat acaaaggata
    65761 taggccatat taccatagct aaacaatcac ttcgaattaa ttgtgttgag atgtcaatta
    65821 cactagcatt ttgagtatac atacttgaaa tccagggtgc aattggtata aatatagctc
    65881 ctactataaa taaacaaatt gttgcaaatt tagttaaata taataaagta ctcttagctc
    65941 ctttaatatc tccacgtcct atatactgtc ccaccaaggt tgtagcagac aaagctaaag
    66001 cattcccaat tacatttatt atggatgcaa ttgacattcc tattgcattg gatgcaattg
    66061 ctgatgttcc catagtaact ataaatactt gaacaatcaa tttacctgca ttaaaaagta
    66121 gttgttcaac tccagctggt attcctatat taaatataga cttttgagtt tcaacatcaa
    66181 tcttaaatgg aaatatttta cccatagata taaattcgtt tcctttaaat aaagctctta
    66241 taattactat acatccaatt attctagcta tagcaataga tatagctgca cctgttatgc
    66301 cataggatgg tgtttgcaaa tttattccta gaggatttaa atcaatacca tatataagta
    66361 tatatcccaa tgttacattt actatattca taaacatagt cacatacata ggtttcttta
    66421 catctccaca ccctcttaaa ataccatttg ctatttgttg tgtcgcaata aatggatacg
    66481 taaataatgt aaactctatg tataattttg catttgattt taccaattct tctgctgaac
    66541 cataaaataa attaattaca ccagttctaa aaacccacat caatattgtt attgtaaagg
    66601 ataatattac tccagacact agagcctgct taatagtttc attcaccttt tcactatctt
    66661 tttttcctat ttgttgagct acaacaacag tagctccaac agatagtgca gcaaatacag
    66721 atataaatat attgtttatt gaatcaacca ttccaactgc agatacagct tcttccccaa
    66781 tatgacctgc catcattgta ttaaatactc ctaaaagcat gacaaacgtc tgctctatca
    66841 ttataggaat tgctaacttt ataacatttt tccttataaa catccctatt cctcttttcc
    66901 ctctttatat aaatttaatt tttaattagt ttatcgaact gtaaattgac aatgcaaagt
    66961 ttagaattgt atcgttcgca ttataatata ctgctttcaa ataatataaa tcttgtttaa
    67021 tatcatttga acacagtata tctttataat tatcttatgt ttattatttt ttatggatac
    67081 cacatttaaa atatttatta atttaatata aatattttcc gttattatta aaagtagcta
    67141 tatttcgtta atattgtatc actatcgtgt agcaataaca ataagtacat tttatatatt
    67201 ttttataata ttatttaatc atccaaactt ttaccacttt ttcaatatat aaaatattac
    67261 actttagatg taacaaaatc gcatccattt aaatattgta ttttatagac taattttagg
    67321 atgtgatact ttggttaatt taaatgcaaa taatctaaat gtaaatatgg tttatcctat
    67381 ttcttccaca gcacccatac gtttcagaag atatactgtt tcatatttag aaaacatgga
    67441 aaatatttat ttaactatag caacatactt tgatacactt ggtttaggca caatgaatat
    67501 cgacaaagtt tatggtcaat gggcttggtt tactgataat atatatgatt taaatctatt
    67561 tgtttttgta ggaaattatc cttatcaaat tgctaaaaac agatatgata catttgtaga
    67621 tattttgcca gtagctatta cttctattgt caatggagat agagtatttt taatttcaaa
    67681 tccttgtttg ttaaattcaa aaattacagt tagatttata tctagtcatc ctactcttaa
    67741 tagaacagtt gattatggca atattagaga ttttattttt taaaactgca acatgatgtg
    67801 ctattaaaaa ataccctaaa tttaatgata ttattaaata actagaatat ttttaattgg
    67861 cacatcatgc ctagctatta taaattcata atattatttt acttaagata agtactgtat
    67921 tttatctact tgtatatttt tatttaccta gtttctcagt tctatatcct atttctttat
    67981 tagctagctt ataaccttct tgtatcattt cttctctcgt taatgcactc cctaataaat
    68041 tgtcaatact cagttgcttt ctatcactaa aatacttatc caataatgat tcctctatat
    68101 cttcctgata tgccaaattt ccttcatgca ttatatattt tacatcaaaa ccttctttat
    68161 ttaatacttt tcccaccaag atacttctat gacatcttat aggttcttgc atagctccta
    68221 ataaaactat cctataaccc atttgacaac ccttttttaa tctttctatt ccgtttaaaa
    68281 aaatatcttc ttttgctact ttctcaaaat ctgcataacc ttcttgcgta tatacatctt
    68341 tattagttct tttagctcca aattcttttc ccatgtatat atatataaat ccggaatttc
    68401 taagagattc gttaaatgcc tctttattgt attgaatatt atatttagaa tatggagttt
    68461 ctctaatgtc aactacacaa tttatgtcat atttttttat catattaata agcttatcat
    68521 atggataatt tgaatgtcct attgcgaata tttccatata aacaccctcc tattctttga
    68581 aattagtatc tatatatgta gatacccgat ttacttaaaa ttaaataaag tattacttta
    68641 aatacccaat atcttttttt cttgatattg tatatttttt tactttatat ccttaaaaaa
    68701 atatacaact ttatatataa aacatcaata tttatatata ttttgtatat taaatacaat
    68761 tatttataaa gtctttaata aaaatttata aatagagcat ctttagaaaa ctattataat
    68821 aaaaaaataa gaggctgtct aaaaatatag ataagccttt tttcataatc gtaattataa
    68881 aaatatactt gatttcatat gaaaaagagt gtctcataaa ctaaaatgtt tactttgaga
    68941 caccaccttt tttattctta tttatacttt gtagacatat tataacatgc gtttcactgg
    69001 tatctgaact tctgtcaacc agtcttcttc actctcttta ttccatatac catctatata
    69061 agattctcta ggatttccaa ccactttata tttattgtcc tctatccatt taaatgcatc
    69121 tgcgtaagtt tttcctaatg ttgaatatgg accattgtgt aatatacaaa ctgcattttc
    69181 aactgcatct aattctttaa attttaatat atccgtatct tcctttaaat catttatagc
    69241 ttgacacatt tcaacatcca tatcagtctc tctatattca ccatcatgat atatattaaa
    69301 acaataatca ggaactgcac atgtacaccc tgttttcatc atttcttcag ccattacatt
    69361 tggaaataga ttaaaaagtt catcataccc ctttaacact tttctcatag aagcaacttt
    69421 aacttttggt aaagacttaa taattacatc attcatattg acttctcctt tcaaattcat
    69481 aaggtaatta cgtagtttaa ttattttata ttcttcactt ttaattacat ccaacatttc
    69541 tttttcttta ttcattaaaa tattttcaac ttcttcagga ttttctacag ctttttttat
    69601 ctcagctaat gataaaccca tttgttttaa agttattatc tgatgtaatt taggtaattg
    69661 ctctgttgta taatacctat attttgtaaa ttcatctaca tattctggtt ttaacaaccc
    69721 tatatcttca taatacctta atgtctttgt agttatttta tttattttag aaaacattcc
    69781 tatagaaaac atctcatcac ctgcgcatta gatttgatta atttaagttt aaactttccc
    69841 cttaggttaa agtcaataca aaataaatta taattgtatt aattcttcaa ttctatctcc
    69901 actcaatacc aaaatatccc ctgtttttat aatggttgaa cctttaggta ttaaaacctg
    69961 ttcctttctt tttatcataa ctattaatat atcgtctggt atattagaat ctattatact
    70021 cttattagcc catttattac cctcatcaac atttacttcg ataagtttag agctaatttc
    70081 tccatcataa tcattaaatg tttttaatac aggtgtatta tcatcaacta aatccaactt
    70141 tctggctaca gttggtatca atgaaccttg tattcctact gaaagcaacg ctataaaaaa
    70201 tattatatgg aatatgtcat tctctatggc tactccttga gtaacagcat aaattgcaaa
    70261 aactactgaa gccgcacctc taagacctac ccacgatatg aataattttt ctttatttga
    70321 gaatttaaat tttgctagaa ctataaatgt tgctaatggt cttgcaataa ctatcatgaa
    70381 tatagatatg gccattgcta taccaaatac atttggtaac ttagaaggga aagataacaa
    70441 tcctaacata aagaataaca ttatttgcat aatccatgaa attccatcaa agaaatgaac
    70501 caaacttttt ttaagaggta tcctactatt tcctataata atacctgaaa tgtaaacact
    70561 taaatatcca tttcctccaa gatactcgct aaatgcataa gaaagtattg caatagctgt
    70621 tataaatata gtataaaatc cttctatctc gaagtttgaa tgtcttaaaa tataaacaga
    70681 taattttgct agtataaatc ctatagctaa cccaaaagct atttgtttta ttaccattgg
    70741 tgcaataagt tctaccccag aattattcat caatgtcaaa agaattagtg tcaacatata
    70801 cgctattggg tcattacttc cactttcaac ttctaataat gatgcaagtg aaccctttaa
    70861 gtttagtttt tgagaacgca acacagcaaa cacagatgca gcatctgttg aagctgcaat
    70921 tgccccaatt aataaacctt caagtaaact agttcctatt accatgtggc aaaacatacc
    70981 tgtaacgcca gccgtaatta ttacacccag tgaagacatt aatatagaag gtatagcaac
    71041 aggtttagcc atattccagt ttgttccaaa ccctccaaaa aacattataa atattagtcc
    71101 aatagaacat aattgttttg tcagttcata gttatcaaaa tagattccta ccatcccatc
    71161 agacccaaat aacatcccta gtaagataaa aatcaataat attggtactc caaatttata
    71221 caataccttg ctagaagtta tacaaatcaa tagtactaac ccacttataa tcattaattc
    71281 tgtcatagca tcaactccat ttcatataaa ttttgtagat taatttacat ctacaatttt
    71341 attacttatt caaatataac atgacataaa ttttataagt tatggtacat aaagttcaac
    71401 aaaaatttca caatacatta aaatgtgagt gttatactta aatttatata tttgt
//
LOCUS       DAMKNB010000010        70429 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.010, whole genome shotgun sequence.
ACCESSION   DAMKNB010000010 DAMKNB010000000
VERSION     DAMKNB010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 70429)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 70429)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..70429
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.010"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            311..688
                     /locus_tag="PC494_000796"
     CDS             311..688
                     /locus_tag="PC494_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HDF3911318.1"
                     /translation="MMIRKIPQAELKVMKFIWKVDVTVTSKDVIEAMEQKYGWKQTTT
                     LTLLSRLVKRGFLDAQKIDRYTHYTIRVKHKDYLSFETKDFLSNIHDDSLRSLISALH
                     DDENIGKDKLDFLESYFDNLKDE"
     gene            681..1829
                     /locus_tag="PC494_000797"
     CDS             681..1829
                     /locus_tag="PC494_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protease"
                     /protein_id="HDF3911319.1"
                     /translation="MNNYMLYVFENLIKTTIVCSLGICLLLFLKRYLFKKFSKRFNYY
                     IWLIIVFRMLLFLFNYTIVYEVKEPKENALGNNITQIDISTDNNLMLYVAYLWLFVTI
                     VIAVYTFIKYTRFKNLVVDVSYDIEDNDINCIYKNLLKELNIKKKIELRGSDELISPA
                     GMGLFKSYIFLPDYPYSKDELTWILKHELMHFKNKDILIKFLVLSVRIIYWFNPLVYV
                     MSNKVNLDCELCCDESVLVECSLKDKKEYALALIKLIKFSKNYNSKILTTEFDKTNLE
                     KRLESIVKKKGKSGILIAVLVFMTSITSFVEVDAQVRIDEGNNGMNNNINEFLLNKTT
                     DKIINIYYKDAPNEIRKFYEDKCELEGKIPRDYDIIEMDMKDYNQLIK"
     gene            1846..2448
                     /locus_tag="PC494_000798"
     CDS             1846..2448
                     /locus_tag="PC494_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan-binding protein"
                     /protein_id="HDF3911320.1"
                     /translation="MLTKLRKIVAIMCCLLLTFTSVAFADTSKEKGGSKETVPEKNLD
                     SFTLSGYIYTYENAPQEIRDEHKQNCEEINIDPKPDDEIFVPESANLMNEDNSKGVYA
                     SYTVSYNIGAKTITIMSNEYLTISTTKVIRKGNSGKEVKAAQIMLTLLGYNVGIDSSF
                     GSKTYNAVVSFQKKYGLSADGIIGPATWDKLGRLTDPTLS"
     gene            complement(2541..3563)
                     /locus_tag="PC494_000799"
     CDS             complement(2541..3563)
                     /locus_tag="PC494_000799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HDF3911321.1"
                     /translation="MDYNDLLKSARENFNGTCKVCKICNGLACAGDVPGMGGKGSGSS
                     FIENRKSLEKIKINMRVIHNVSKPDTSIELFGRKMSSPIFAAPVSGTILNMGGKVSEK
                     EYIEPVVRGCSNSGIYAMVGDTNVDTFLLDNLDVLKDNRGNGIVFIKPWNNSKIIDKI
                     RLSEEAGAFAVGVDLDACGLINNQFQENPFSPKTIDEIRELVESTRLPFIIKGIMTVD
                     DALMAVESGASAIIVSNHGGRVLDYTPGTCEVLPDIAKSVKGKITILVDGGVRTGVDV
                     VKMLGLGADAVLMGRPFVTASFGGGLDGVEFFIEKVRNELCETMILTGCQNVKDIDGR
                     VIWNLL"
     gene            complement(3892..4074)
                     /locus_tag="PC494_000800"
     CDS             complement(3892..4074)
                     /locus_tag="PC494_000800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3911322.1"
                     /translation="MYKDKSDECIHLMTAYIDSISGYYSFIDTQLEDFMMKYGENIVD
                     SNLHSIMMLLCKWGLS"
     gene            4387..4806
                     /locus_tag="PC494_000801"
     CDS             4387..4806
                     /locus_tag="PC494_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3785 domain-containing protein"
                     /protein_id="HDF3911323.1"
                     /translation="MSLYKFIYDDKEYLLKEENCSALINDEENPVQGVSISKIIDILN
                     EAEEVDFDVEYYQEACPLCLEGVKEKKKFFPFLEYHFYIFSKDGEYVISNISVDYKGL
                     SFNKLSRANKVDNSYIVSVIICENCQDYIVQIENCIV"
     gene            4937..6778
                     /locus_tag="PC494_000802"
     CDS             4937..6778
                     /locus_tag="PC494_000802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HDF3911324.1"
                     /translation="MEEIDDTILDSMFKLTLNERLLTNNDFIENKIDVVKNLIDCYKT
                     EQNSLMLLKSNFLLALLYGIQGFSEKMKEYILISCKYIDKCLPKDYKFLARFYSQIAI
                     LSLKNEDVNKANLYMDKFNLICDENNFLIEEIIFKSQLIYIKASKCIESSVIIKEIET
                     LYIKIKEINDFNCKKIYFFIIGKIYFLFLDDALIAKVNFLKARKYADLLKDMQVSSLC
                     NIKIGECECSFENYECSMEYFNEVISNKKYRNVNIIQKYRASNNITKILIKTRNYPVA
                     INNLAKSEVYLEKIKNHSLKEVEKFDLFISLAMYYAKSNEKSFEQSICYLDRAKNILN
                     MIKNIEEYIIYDLEIIYHQAKIYYIFGYYDNALNTNKKLLEKSKNAKNYNYVKLAYKS
                     IYLCFEKIQNYEMSMKYFKMYYELKMMYIKARNRNYIDSLNYRHEYIEKEINNMRKVK
                     LDLDKKKYVDHLTSAYNRTFLNDFLEKQEVSEYCTAFMIDVDYFKEYNDTYGHYNGDI
                     ALKNITIIIKKYLKKDMLMIRYGGEEFLILSVCKDYKKSKIFGRKLCRIVKKFLNNNL
                     TVSIGIDTCKNSSIDIKEIIENADKALYKAKESGRNRCLHYHDFKNF"
     gene            6805..8691
                     /locus_tag="PC494_000803"
     CDS             6805..8691
                     /locus_tag="PC494_000803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HDF3911325.1"
                     /translation="MKRSLIEDLKRNINKIEYDMLTKFYLNLTDLNYILDYHKDLLNT
                     KLEDNSRVYTLYLISLINYIKKDREASYNYLIESLKYIKKLSLKDDSDIISKIYIYLT
                     LSAISIRKYDKVNNFYFSAKKIIRQNHLNELLVLLNMSLCVEISALYQTKTDVIALVE
                     EVSFFKTLKNKALVSRANYIFGRVYLYLFNNFIKSMEYLIECLKLAQENNLYSIEAFC
                     KCIISLCYLESGNNVEAIKYINNVLDVAHSNNSISVTERVSIKIDLIWAYLKEDMNKE
                     AEVILLKTIKLMKVVEGVYKDYLYSFIFLYSAEIELKKDNCSFEKVNTYLILSKNIYK
                     SFGDVFIYNSKLDYIYKLYGDLYIKFGNIDEGISCYIKGLNLVKKSSLNLRKISIFYG
                     LIANGYELKKDFKLAIEYYKSMDWYSDRWEKNNSYKTSQAIHKQYELRQKQESLRLLV
                     DDNKKLENDILKDGLTKLYNRRYLEQQLDLFNETRDKNMVAILVDIDCFKSYNDNYGH
                     LAGDKVIVKVTDIIRSVFIDITEHIIRYGGEEILILVDSIESIGVEEIDNIELYIKRV
                     FKLLEFEGIEHIYSKIKNYITISAGVSIKRCRSRKDVEILIEDADKNLYKSKKAGRNQ
                     YIII"
     gene            8699..10699
                     /locus_tag="PC494_000804"
     CDS             8699..10699
                     /locus_tag="PC494_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDF3911326.1"
                     /translation="MILLRKKIGIIASDIELKERIEELYREDVENGTIIIDILNLDLM
                     ENQGRILVEKGAQAIIGRGGGYSLVIDTVNVPVIPMNMKSTDLLRAIEIAKKYSKKVV
                     LILGDNEVSFDYVGWRNVISTEITEEWFESKYEIRSKVVKYIDQKDEIVIVGGGLACS
                     FARQYGIDSVFATASDESIREAVEYCKKLLDTLGEEKFNNEVLRNILDGIKDGVIAID
                     SNGSIILYNESAKNMLKVERKCALNKYILDVFPKMEWMLDCLHEKEDVEDRKIRNINN
                     LIVNTRTTLIKVDNSTYGVLGIIQDITKLQNLERKIRFDLNQKGLYARYTFDDFLFKD
                     KLTKEFIEEAKKIGKSDYTTLLYGESGSGKEIIAHSIHNISKRKDRPFVAINCATIAE
                     NLLESELFGYEEGAFTGARKGGKRGLFELAHGGTLFLDEINSLSFNIQTKLLRVIEER
                     QIMRIGSDYIIPLDIRIIAATNESLTEKIVMGTFRADLFYRLSSLEINIPPLRDRRED
                     IIPLFNNFVNEVLKDDGLNGINSIDENFVLTKDEMDKLYNYSWPGNVRELKTIAQKYV
                     VTGKIKLRQDRDFKTKKLLPNSEVDKFNSETTASVEVQDESINISKINDGKISIDIKE
                     VNKYVEEKIISMLFAQGLSKNEVAQVLGISRTSLWKKYNKNI"
     gene            10961..12220
                     /locus_tag="PC494_000805"
     CDS             10961..12220
                     /locus_tag="PC494_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HDF3911327.1"
                     /translation="MSQSMVGKHAMWPKENDVIFSISGRAQAAEKAFGMDNVINATIG
                     ALMDDSGKLITMKTVYEEYKALDNCEIGAYAALEGQPDYLEAVKKVFFRDYLPEGHIR
                     VLASPGGSGAIKLAVWNYTNEGDEVLTSDWFWSPYVSIAEEANRKVVNYQLFDENRRF
                     NFESFKEKFVNIAEKQGRVFTIINTPAHNPTGYSVADDEWDKILDLSKEVAKDKDKKI
                     IFFVDSAYIDFAGDDDVCRKFFKKFSNLPENVLVLVGFSMSKGFTAYGMRMGAIICIS
                     SSEDVAEEFHYSCVHSCRANWSNCNRSAMAVLSNIVNDPKKFKEYEDEKEIYKNMLTR
                     RADVFVKEAERVGLEILPYIAGFFVSIPCDNPKEVCEELTKHNLFAVPLKMGLRFAVC
                     AVSEDKCKKAPSIIKEALESLEVKINN"
     gene            12281..14068
                     /gene="iorA"
                     /locus_tag="PC494_000806"
     CDS             12281..14068
                     /gene="iorA"
                     /locus_tag="PC494_000806"
                     /EC_number="1.2.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="indolepyruvate ferredoxin oxidoreductase subunit
                     alpha"
                     /protein_id="HDF3911328.1"
                     /translation="MKQLMTGNEAIARGAYEAGVKYASAYPGTPSTEILENIATYKDA
                     IVAEWAPNEKVALEAAIGGSIAGARTMASMKHVGLNVAADPIFTYAYTGVNGGMVLIT
                     ADEPGMHSSQNEQDNRMYAKFAKIPLFEPSTSQEAKDMIKEAFEVSEKYDTPVLYRVT
                     TRLCHSKGLVECYDREEVEIKEYVKNAKKMVTVPANAQIRRGVVEERMEILKKFSNET
                     DLNYYEINDTKIGVIASGMCCNFAKEVFGKNASYMKLGFTNPLPYEKIKEFAEKVDKI
                     YVIEENDPFIEEQIKAYGIDCIGKDVIPPYGEMTPDVLRKAIFGKTNDTIEYKSELVT
                     PRPPSFCAGCPHRGFFYELGKRKNLIVGGDIGCYTLGFAPPYNGIDYVVCMGSAFGTA
                     HGAQKVLNMKDDNEKRLVGVLGDSTFFHTGINGLLDVVYNRGNSISVILDNRITGMTG
                     HQENPGSGYTLQGAKTKEVDIEGLVKACGIEHVRVINPNNLKEVNEALDWALAIEDEP
                     SVIITRWPCVLKKFSKEDIEEFNNPFKTKCKVDHDKCIGCKLCLKTGCPALSFDKENK
                     LSNIDRNQCVGCGVCAQVCPKQAIVKEEK"
     gene            14070..14645
                     /locus_tag="PC494_000807"
     CDS             14070..14645
                     /locus_tag="PC494_000807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="indolepyruvate oxidoreductase subunit beta"
                     /protein_id="HDF3911329.1"
                     /translation="MTKSILLVGVGGQGTILASKLLTMGLMEAGYDVKMSEIHGMSQR
                     GGSVSSQVRYGDCVHSPVIEIGGADILVSFEKMEALRWFNYLKPEGKALVNNHRIDSM
                     TVLIGGAEYQESDIDAELSRLNAKVINAADKAEELGNSKIMNVILLGCLVKSMQLESI
                     DWEKIISENVKPKFVELNIKAFHEGMEMVSK"
     gene            14698..15768
                     /gene="buk"
                     /locus_tag="PC494_000808"
     CDS             14698..15768
                     /gene="buk"
                     /locus_tag="PC494_000808"
                     /EC_number="2.7.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="butyrate kinase"
                     /protein_id="HDF3911330.1"
                     /translation="MTYRILAINPGSTSTKIAVYDGEEQILVKTIDHPAEEIAKYNTI
                     QDQFEMRKEAVLNILKENSIDLKSLSAIVGRGGVLPPVKSGAYLVNEEMIDVLRHRPV
                     LEHASNLGAVVAHAISEPLGINSYIYDSVAVDELIDVARISGLCGMDRSSAGHALNTR
                     AMALKYAKDKGKDYKSLNLIVAHIGGGVSIYLHEKGRMVDMLSDDEGPFSPERSGRVP
                     ATKLVAACYSGQYSEREMTKKIRGKGGIVSYLNTVDAREVEKMIAEGNEEAKIIYEAM
                     AYQLAKGIGELATVVDGKVDAIIITGGIAYSEMFTSMVKKKVEFIAPVEIMAGENELE
                     SLAFGTLRVLNGEEEARIYSEN"
     gene            15986..16687
                     /locus_tag="PC494_000809"
     CDS             15986..16687
                     /locus_tag="PC494_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3911331.1"
                     /translation="MGKISLKSMIRLFSGFFIFAISSVLMINAHVGLMPWDVLHQGLS
                     IKLGITIGQASIMVGVVIVILDAVFGENIGWGTLLNMTFIGIFIDLVIFSGVIPHASN
                     TYIGVFMVVIGIILAAIASFLYLGVCLGSGPRDGLMIALQKKTNKSVRLVRTILEILA
                     LVVGWLLGGSVGIGTLVSALGLGYVLQIVFRIFKFDTKLLKHRFIIDDIREWKEKKSN
                     EHKCKSSIVIKNEQN"
     gene            16747..17253
                     /locus_tag="PC494_000810"
     CDS             16747..17253
                     /locus_tag="PC494_000810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HDF3911332.1"
                     /translation="MELWDLYNADGIKTGNVIKRGNSIEEGYYHLAVEVWILNSNSQI
                     LIQKRSKSKKTLPNMWGMTTGCIVSGEDSLEGAIREAKEEIGIDITKDEMKVFRSMIH
                     EDTLWDVYLVKKEYDISKAILQEEEVSDIKWVSTDEIRQLLKEGLFFEYPEIYELLYE
                     IDNNKLNI"
     gene            17428..18450
                     /locus_tag="PC494_000811"
     CDS             17428..18450
                     /locus_tag="PC494_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HDF3911333.1"
                     /translation="MEDNKGLARDSSKYKIVSISVVVIILITFWYMLNMVLLTFIMTF
                     IFYNLLVATRKRIKKFSSLNIPDSLIIIVLYALFAILLVLISYAVVPIIIVQLTELSR
                     VFSDFDVNQFAQSLGPKLYPIVSKLDFNKYISQAGLLIASTATKVGSFGVNILLAFLL
                     SLLLLLEKNEIKNFGDKLSDSKISFIYNSLVFFGKSFVKNFGEVMKVQVMIAFINSVV
                     SMIFLGFMGFPQIWALGFMIFVLGLIPVAGVIVSLIPLTVIAFNTGGITKVFGVLLMI
                     CIVHAVETYILNPKLMSNRTKLPVCFVFIILLVGEHYLGVWGLLIGVPIFMFLMDILG
                     VKFTSR"
     gene            complement(18597..18905)
                     /locus_tag="PC494_000812"
     CDS             complement(18597..18905)
                     /locus_tag="PC494_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1540 domain-containing protein"
                     /protein_id="HDF3911334.1"
                     /translation="MKNNNLNCAATNCAYNTSGYCYAGSIKVDGMQATTTENTYCASF
                     EDKYTSGITSRSNETNQVDTDNIHCEAVKCKYNKNELCKAEKVHINERNASCETFEMK
                     "
     gene            complement(18965..19393)
                     /locus_tag="PC494_000813"
     CDS             complement(18965..19393)
                     /locus_tag="PC494_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3911335.1"
                     /translation="MNNKLHELEKNLPEISCSFCTHLSFKGPSLDYRYDIRCVISDTK
                     PDFRGCCEYFEPEYTELNTGDLDNLYINFLETCLKVNYNDYINSMYWKLFKERTLLEN
                     NFKCSICGSTENVDVYHVNKNLGRETSKDVVVKCDKCNCK"
     gene            complement(19616..21073)
                     /locus_tag="PC494_000814"
     CDS             complement(19616..21073)
                     /locus_tag="PC494_000814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon starvation protein A"
                     /protein_id="HDF3911336.1"
                     /translation="MTTFLIGLAILLIGGALYGAYCEKVFGPDDRKTPALAQSDGVDY
                     VPMKKWKNSLIELLNIAGTGPILGPIQGILFGPIAFILIPIGCVFGGALHDYMSGMIS
                     IREKGAQMPSLISRFLGNKVFQVYNIFLCLLMLLVGAVFIYTPGDLVVTQILNMKSTI
                     NNPVVWIVYGLIFLYYLCATLFPIDKIIGKVYPIFGAILLLSAAGVGIGIFTQGYDLA
                     NLSLANWKGIHPDGIPLIPTFFVTVACGIVSGFHSTQATLIARSVSNEKEGKTTFYNM
                     MILEGLIAMIWAAAAMGIYNKGIPKELVGSPDVIGLVARDLLGSIGGIIAIIGVIVLP
                     ITSGDTALRSLRLMLADYFHYDQKEKKHRVILSICIFIPVIAILIFAKLSASGFNILW
                     RYFSWSNQTIAIFAFAMITVYLIIKEKNYIISLIPGMFYSFVIFSYIFNAQIGFNLNI
                     NISYVLAAIFTVLYAILTVRSGRKLKSKADTKLAD"
     gene            21491..22405
                     /gene="nadA"
                     /locus_tag="PC494_000815"
     CDS             21491..22405
                     /gene="nadA"
                     /locus_tag="PC494_000815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quinolinate synthase NadA"
                     /protein_id="HDF3911337.1"
                     /translation="MDKDLTYQIKELKKEKNAIILAHFYQPPEIQELADAVGDSYYLS
                     EIARDCKEEVVVFCGVRFMGESAKILSPEKTVLMPVSNAGCAMADMVDEEGVIKLKQQ
                     YPNALVVCYINSTAKVKAHCDVSVTSSSAIKILENIDNKEIIFLPDKNLGGYIAEQFP
                     DKNFIFWDGYCKYHNNIRAEEIIELKDKYKNAEVLVHPECKKEIRDLGDYVGSTSGII
                     KYATNSKNKDFIIATEEGILHELKKNNPNKNFYIPGGKILCTDMKKTTLENLYSTLKN
                     MENEVIVEDEIMEKALNSLLNMHKLAEG"
     gene            22418..23719
                     /locus_tag="PC494_000816"
     CDS             22418..23719
                     /locus_tag="PC494_000816"
                     /EC_number="1.4.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-aspartate oxidase"
                     /protein_id="HDF3911338.1"
                     /translation="MNLEQDVLIVGSGVSGLYCALNLDKSLNVLVVSKSTIENNNTYL
                     AQGGISTARNIDDIESFVEDTMKAGQYKNRVEAVQVLADESIENVGQIVEYGMPLDKE
                     NGEIDYTREGAHSVNRIVHSKDNTGEVVFKTLLKEAKTRENITLIEDAYLLDILKDGN
                     KCIGARIFKSKKEIHVFSKIVVLATGGIGGLFKNSTNQRHLTGDGIAIALRNNIKIEN
                     LEYIQIHPTAFYEENNEGRRMLISESLRGEGAKLLNKNKERFVDELLPRDVVSKAIFE
                     QMEKDKLPYVYLDATHLDSEYLINRFSFIYNECLARGTDITKECIKVSPAQHYFMGGI
                     HVDLDSKTSMENLYAVGEISCTGVHGANRLASNSLLEGLVFSKRAAKNINSVIDNVKV
                     KFIDVPDMDIDIEQVKKENKILVIKEIERTSEDFGDELFDY"
     gene            23700..24536
                     /gene="nadC"
                     /locus_tag="PC494_000817"
     CDS             23700..24536
                     /gene="nadC"
                     /locus_tag="PC494_000817"
                     /EC_number="2.4.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylating nicotinate-nucleotide
                     diphosphorylase"
                     /protein_id="HDF3911339.1"
                     /translation="MNYLIIDRMIQDALIEDVPSEDITTNSIVDENSKSTVDLICKQD
                     GIIAGLGVFKRVFEILGDVDVKLYKNDGDRVKNREKIAVLTGSTRNLLVGERVALNYL
                     QRMSGIATITSRYVEKLEGTNTKLLDSRKTIPNLRILDKYSVKVGGGCNHRFNLSDGI
                     LLKDNHIGAAGSVKKAVELARKNTSFVRKIEVEVETLDMVKEAIEANADIIMLDNMSL
                     EMAKQAVDIINGRAIVEFSGNVNLDTIEDIGKIGVDVVSVGALTHSVKALDISMKNLR
                     NI"
     gene            24792..25124
                     /locus_tag="PC494_000818"
     CDS             24792..25124
                     /locus_tag="PC494_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsrE family protein"
                     /protein_id="HDF3911340.1"
                     /translation="MKVAYIFSSTNTHKILDKMIIPQLEQGTHGVDVLGMFFFMDNTL
                     FLSKGNPVGERLSKLHEKTDMIIMACDQCAIERGIENNLVDGATIGCFPNLYACLGSA
                     GVDQVITL"
     gene            25286..25471
                     /locus_tag="PC494_000819"
     CDS             25286..25471
                     /locus_tag="PC494_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3911341.1"
                     /translation="MSEKYADKLEIKLYQAGKDFSYIKKYGIITKGTLIINQKKKYDR
                     LNKDTIERAIVEAINNN"
     gene            25498..26583
                     /locus_tag="PC494_000820"
     CDS             25498..26583
                     /locus_tag="PC494_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HDF3911342.1"
                     /translation="MNILEIVLNGVKDTIVASIVTLNGASGWLMISFILAGVLHNVLT
                     PRRFQKQLGNKKFSSLIKSTISGMFLPICSCGVIPLGISMYYSGAYLGPVLAFMTSTP
                     IINPIAVVLCLGLLGPKVTIIYLIAGFLVPFLVGFLGNCFGKEELSLHNDSEEEVIEL
                     EEEKRSFMENMIDGLKWSFGELALTISKYVVMGMVFAGFITTIFPNSIIQKYLGNPGL
                     LSLGSIAILACVMYVCAVGHIPFIAALVASGASPGIAITFLIAGAATNLPELISMFKL
                     IGKRTVIIYSVTLTLSSIIIGYITNLLLVNNNSVNLDATNSSIQLANKLMLNIPDSFE
                     YVCTILIILFAFKSIIPKMKEVIGNHA"
     gene            26576..27034
                     /locus_tag="PC494_000821"
     CDS             26576..27034
                     /locus_tag="PC494_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3911343.1"
                     /translation="MLKKIVIISCIVVVLIILSKIVDDNIKEDASIPNVNKETLEYFR
                     KNYKEDIITCAEEDLNNDGKKDLVVIYKKSNNSNEMVVVVSDKNSHYITKPIPAPIEN
                     QTITFKNIDDKAPIEVIVSGSKNGNVGYAIYRVEGKKFVDLFGEDMDKCC"
     gene            27069..28160
                     /locus_tag="PC494_000822"
     CDS             27069..28160
                     /locus_tag="PC494_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDF3911344.1"
                     /translation="MKLSKKIQALILFGVMGTSILTGCSSKPKEKEEAKTGKDDYTIT
                     VGYYNCDHMTAGPVAESAGIYKDLGLNVKTVGNGKVPEAMAAGKMDAGYIGTKGLVGA
                     IPKGSPITIAANNHTGGSEYLIVSKDIKEPKDLIGKKIATDMSDFLWTSDYGPETGLP
                     TDPSKYEVVNMDSDKDKYLALKTGKIQAFTSCDPWGSVAENDGAGKIIASTQYKEKAN
                     GKEYNCCSFSLNKNFIKEHPDLAKKLVLAHTKAIEYIYTNPAEAAKIFAKYYNVEEEV
                     ALRTIYKKTVGEGRTLTWKVTGEEYKNNLQMYKDLKALDDIPKYEDTIDTSLLDSCGA
                     DDFDKFIKEKVNPEFPEGMSYEDWKAKVL"
     gene            28165..28389
                     /locus_tag="PC494_000823"
     CDS             28165..28389
                     /locus_tag="PC494_000823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3911345.1"
                     /translation="MENMKNIIILFIIILGSIFIIFFNFEDKEEIKGKLRIGVSDDTS
                     GFVINYMVNRDYFENIKVSDIMDIFTINDC"
     gene            28399..28962
                     /locus_tag="PC494_000824"
     CDS             28399..28962
                     /locus_tag="PC494_000824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3911346.1"
                     /translation="MQWALSSEEIDIAIICKDAAKQYVNVNSGFEIVGTVVQNSDIFL
                     LSDNNPEKIGVIQNRDYQSELVKKYYKNVEVAPLLGTALAYGLESNLVDGVVIDCIKS
                     IGLEGKRKSTTKLGDYDTYVLVVSKEFKKSKAYSDFITLYNKSVDALKNKATFKKALK
                     EYRNIRNIDMEEISNWKLKFLKIKAID"
     gene            28923..29552
                     /locus_tag="PC494_000825"
     CDS             28923..29552
                     /locus_tag="PC494_000825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF3911347.1"
                     /translation="MEIKISKDKSDRLTKKKTDGSMDILYKIILLVIIFLVWHFAAKD
                     IGSSLLLPMPVDVIKGFFFCVTDAETVTNLFITLQRVLKGFMYALLFGLPIGFIMGFS
                     KTFERVLSPVVDSVRQVPIMAWVPLTIVWFGIGDGPTIFLIAFSGVFPIILNTIQGVR
                     AISKDYYNAARSMGASPIVIFTNVIVPASLPDILTGSRIAISTGWMSVI"
     gene            29592..29729
                     /locus_tag="PC494_000826"
     CDS             29592..29729
                     /locus_tag="PC494_000826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HDF3911348.1"
                     /translation="MVQAQTLMHTDVLIGLMIFAALIGFIIDRVLKFINKILCRWRFA
                     D"
     gene            29729..30481
                     /locus_tag="PC494_000827"
     CDS             29729..30481
                     /locus_tag="PC494_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF3911349.1"
                     /translation="MKLSVRDINKTFVNNRVHTKVLEDISMDIDDGQFVCLLGPSGCG
                     KTTLLTIIGGFQKSERGDVFINDKRVKKPGIDRAFIFQNYALFPWKTIRGNVLFPMKQ
                     QKIPKEKREEMLEELLVMSDLKGKEKLFPHQLSGGMKQRVAMIRALACNPEVLLMDEP
                     LGAVDFQMRQNLQEELERIWIKKKITALMVTHDVDEAVYMSDRVIVMSRDKGRIIDDI
                     NIDIPRPRIRGSQKYEEYKNKLTDTLSKCYEV"
     gene            30494..30979
                     /locus_tag="PC494_000828"
     CDS             30494..30979
                     /locus_tag="PC494_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3911350.1"
                     /translation="MSQIEKYNSLDNTQQKIRISIMDMIIDKGSSVTLQEVTEYISKK
                     LNIEKEYIERTLQYFIYKNIMVVDGNSINFIYPVSALPTNHKVTLRDNRSFSAMCAID
                     AIGTSCTFNQDIKINSICSATGKEIEVIIKNEKIEYVNNPNLRVLHINLDKHLNWAAS
                     C"
     gene            30986..31135
                     /locus_tag="PC494_000829"
     CDS             30986..31135
                     /locus_tag="PC494_000829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3911351.1"
                     /translation="MNFFWTKSDFDAWTNEAGLSNDEDIYCLDINEAIVESYKIFKLK
                     QKVLS"
     gene            complement(31272..32093)
                     /gene="yidA"
                     /locus_tag="PC494_000830"
     CDS             complement(31272..32093)
                     /gene="yidA"
                     /locus_tag="PC494_000830"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HDF3911352.1"
                     /translation="MYKLIALDIDGTILNTQKRITPEVFESIQEAKRAGAKVVITTGR
                     PLPGVKELLNQLNLTDEGDYVICFNGAIIQEVKSEKIIHDVEMSLDDFDFIYNNVCKK
                     YKTKIHINTMTNLITPNETPGKYTLHEAKLNNIEVKYIQKDKIDESIKICKIMIVDEP
                     ERLEEIIQQLPKNLFNKYTIVRSAPFYLEFLGKTTNKGTALKTLCTNLNIPIENAIAV
                     GDEENDQHMIKYAGLGVAMGNARNSIKEIADYVTDTNNENGVAKVINKYILNKAI"
     gene            32586..34280
                     /locus_tag="PC494_000831"
     CDS             32586..34280
                     /locus_tag="PC494_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M3 family oligoendopeptidase"
                     /protein_id="HDF3911353.1"
                     /translation="MKFSEFKYERPNYNSMKKEFLSCVEDINNSRNYKEQQKNIHKIN
                     LLRNKIETLSNIASIRYSTDTFNKFYKEEKNYWDEYMPLYEELNSYFYNAIVNSKFKY
                     DLIKEFGEQFFTIVEYSLKSFSKEIISELQEENKLCSEYTRLLASAEIMFDGKIRNLS
                     GMGKFMYSKNRKTRELANKAYYNFFEENETKFDDIFDKLVKLRDKMSKKLGFEDFVEL
                     GYVRMMRSDYREYMIKNVRKQVLKYVVPMANELYEKQAKRIGLEYLSYIDEGVEFLTG
                     NASLKGDSRYIIKNGKRMYSELSKETNEFFDFMLENELMDLETKKGKGAGGYCTYIPD
                     YKSPFIFSNFNQTADDIDVLTHEAGHAFQLYMSRWIDMPEINFPTLDSCEIHSMSMEF
                     ITWPWMDLFFKEDTDKYKFTHLSSSIKFIPYGVIVDEFQHYIYKNPNVDKSKRKEIWR
                     FLEKKYLPHRKYGDNSFLERGCWWFKQGHIFKNPFYYIDYVLAQICALQFWKKMIQDR
                     DAGWKDYINICKVGGTKSFLDIVSMGNLYSPFDDGCIESIIGDVKSWFDEINDSKL"
     regulatory      34612..34722
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            34826..35197
                     /locus_tag="PC494_000832"
     CDS             34826..35197
                     /locus_tag="PC494_000832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GrdX family protein"
                     /protein_id="HDF3911354.1"
                     /translation="MIIITNNPKVKEEVQGREVLFKDTTYIGILEASRDLIHEGYELL
                     SHPLYGSVKPNETPYRTVILKKGNRLDINSLTLIEEAIITASKFQNNKKTPKWTESVQ
                     DDFRVIDYDIFYNTIQRMQYE"
     gene            35294..36241
                     /gene="trxB"
                     /locus_tag="PC494_000833"
     CDS             35294..36241
                     /gene="trxB"
                     /locus_tag="PC494_000833"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HDF3911355.1"
                     /translation="MENVYDLVIIGSGPAGLAAGLYGARAKLKTLILEKDKTGGQIVI
                     THEIANYPGSVPNATGPSLIARMVEQCKEFGAEMLRDNIVDTELDGDIKVLKGEKAEY
                     RAKAVIIGTGATPRKIGCPGEKELTGKGVSYCATCDADFFEDFEVFVVGGGDSALEEA
                     MYLTKFARKVTIVHRRQGFRCAKSVEEKAKANPKIEFLLDTVIEEIKGDGILESVVFK
                     NKVTGETHEYFADEEDGTMGVFVFVGLDAQTDLFKGKVDMDEKGYIITDEDMRTNIPG
                     VFAAGDCRSKTLRQVVTATNDGAIASIVAEKYIDEKFGN"
     gene            36345..36662
                     /locus_tag="PC494_000834"
     CDS             36345..36662
                     /locus_tag="PC494_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol reductase thioredoxin"
                     /protein_id="HDF3911356.1"
                     /translation="MLDLDKATFEEEVLNAEGFVFVDFWSEGCEPCKALMPDVHKLAE
                     TYGDKIKFCKMDTTKARRLAIKQKVLGLPTMAIYKDGEKVDEVTKDDATVPNIENMIK
                     KYL"
     gene            36931..38217
                     /locus_tag="PC494_000835"
     CDS             36931..38217
                     /locus_tag="PC494_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006439082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine/sarcosine/betaine reductase component B
                     subunit"
                     /protein_id="HDF3911357.1"
                     /translation="MRLELGKIFIKDIQFGDVTEVKDGVLFINKQEMLQEIGGDEHIK
                     SIDIELARPGESVRITPVKDVIEPRVKVEGNGGIFPGIMSKVDTVGEGKTHALKGVAV
                     VTTGKIVGFQEGIIDMTGEGAKYTPFSKLNNVVVIAEPIDGLKQYAHEKAVRMIGFKA
                     AMYLGEVARNLTPDEVSVYETKPLLESIKEYPELPKVGYVYMLQTQGLLHDTYVYGVD
                     AKQIVPTLLYPTELMDGAIVSGNCVSACDKNPSYVHINNGVVEDLYARHGKDINFVGV
                     IITNENVYLADKERSSNWTSKLCKYLGLDAVIVSQEGFGNPDTDLIMNCKKIEMQGVK
                     TVIVTDEYAGRDGGSQSLADADVRADAVVTGGNANQVVVLPKLDKVIGHLEVVDVIAG
                     GSDGSLRADGTIEVEIQAITGATNETGFGHLTAKGY"
     gene            38329..38802
                     /locus_tag="PC494_000836"
     CDS             38329..38802
                     /locus_tag="PC494_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011986236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_except=(pos:38461..38463,aa:Sec)
                     /transl_table=11
                     /product="glycine/sarcosine/betaine reductase complex
                     selenoprotein A"
                     /protein_id="HDF3911358.1"
                     /translation="MSLLSNKKVLIIGDRDGIPGPAIEECVKTVEGAEVVFSSTECFV
                     UTAAGAMDLENQNRVKDAADKFGAENVVILLGAAEAEAAGLAAETVTAGDPTFAGPLA
                     GVALGLSVYHVVEEPIKSLFDESVYEDQISMMEMVLEVEEIEEEMSGIREEFCKF"
     gene            38834..40144
                     /gene="grdB"
                     /locus_tag="PC494_000837"
     CDS             38834..40144
                     /gene="grdB"
                     /locus_tag="PC494_000837"
                     /EC_number="1.21.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_except=(pos:39881..39883,aa:Sec)
                     /transl_table=11
                     /product="glycine reductase complex selenoprotein B"
                     /protein_id="HDF3911359.1"
                     /translation="MGKLKAVHYINQFFAGIGGEEKADTKPHVAETLPPISLQLDKLL
                     GEDIEIVGTVVCGDSYFNENIDSASEEVLSMVKGFEPQLFIAGPAFNAGRYGVAAGTI
                     TKVVKDALNIPALTGMYVENPGADMFKKDVYVVETSDSAAGMRKALPKIAKLAVKLAN
                     GEEIGTPKDEGYIARGIRVNYFHEDRGSKRAVDMLVKKIKGEPFETEYPMPNFDRVDP
                     SKAVKDLSKCKIALVTSGGIVPKGNPDRIESSSASKYGTYSIAGVMDLTEETYETAHG
                     GYDPVYANLDADRVLPVDVLRDLEKEGVIGKLHETFYTTVGNGTSVANSKKYASEIGA
                     ALVADGVDAVILTSTUGTCTRCGATMVKEIEKTGLPVVHMCTVVPISLTVGANRIVPT
                     IAIPHPLGNPALDPTEEKALRRGLVEKALNALTTEVDGQTVFEK"
     gene            40400..41932
                     /locus_tag="PC494_000838"
     CDS             40400..41932
                     /locus_tag="PC494_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014520415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III family protein"
                     /protein_id="HDF3911360.1"
                     /translation="MTYPVLKGAGYVLIHTPDMIVQNGSTCTVERATNPDSEFLKEVS
                     NHIRSYEDVVNYMPNQVYIGNRRPEELRDLPMPWCEQKIEGTRNGKFGEIMPQDEFIA
                     LMQISDAFDLVKLSQEFIDEVKPKIENNYPEIAPFVGKLKGDDIEEGKELVATHIAEG
                     LYHDGKFVGYVKRAHDVDVNLNAHTMFENLVVKASGVLSAIQMLRHSKIDPAEIDYVI
                     ECSEEACGDINQRGGGNFAKSIAEIAGLQNATGSDTRGFCAAPTHALIQAAALVKAGI
                     HKNVMVVAGGASAKLGMNAKDHVKKGLPVLEDVVGGFAVLVSENDGVNPVIRTDLTGK
                     HTVGTGSSPQAVMTALITSGLDRANLKITDVDVYSVEMQNPDITKPAGAGDVPEANYK
                     MIGALAVKRGDLEKKELKDFVSNKGLPGWAPTQGHIPSGAPYIGFLIDDLTTGNRNRA
                     MIVGKGSLFLGRMTNLFDGVSFIAERNTGVTEETSGISKDEIKKIIAESMKKLALDML
                     EE"
     gene            41943..43088
                     /locus_tag="PC494_000839"
     CDS             41943..43088
                     /locus_tag="PC494_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine reductase"
                     /protein_id="HDF3911361.1"
                     /translation="MSKKVIADVFLEVANAIESGEFGKKVKIGVTTLGSEHGVENMVN
                     GAQLAKSNLFDIVLIGPKVETDLEVVEVNDEKEMHAKMEELLDSGYIDACVTMHYNFP
                     IGVSTVGRVITPAKGKEMILATTTGTSATNRIEAMVRNAIYGIATAKSMGNKCPKVGI
                     LNVDGARQVEKCLKELKDNGYDMEFADSIRADGGCVMRGNDLLVGAPDVMVTDTLSGN
                     IFMKVFSSYTTGGDYEAQGFGYGPGVGEDYDRKVLIVSRASGSPVVANALKYAYDVVK
                     GDISNVARNEFAKVKKAKFDDIISSLTKKEVKAEKVEVKMPDKEIVTRQIAGVDIMDL
                     EDAVSELWKNGIYAESGMGCTGPIVLVNEAKGDLAVETLVKAGYTAK"
     gene            43398..44477
                     /locus_tag="PC494_000840"
     CDS             43398..44477
                     /locus_tag="PC494_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HDF3911362.1"
                     /translation="MSRVKNVVELLETKGVDALYLTKKTNVNYISGFPDEEAYAVICK
                     DGNFLVTDSRYMELAEKVCKDFEIINWHNFDRSVAKAVKSVCDKVGIKKLGFERTNIV
                     FDKYEELKNLIEKDNGELIPTENIVETLRYVKDKDEIKNTRKACEIADKALEELIPHI
                     KAGVSEIELATKLEYFMKMNGAQNIGFETILISGAKTSLLHGKPSDKIIEKGDFVLID
                     YGAMYNGYISDTTRTFIVGGASEKQLEIYNLVKEAQNVGVENMKAGVHATIPDAEIRK
                     VVKKYEDYYYQGIGHGVGRDVHEEPFIGNYGDKIIEEGCIITMEPGIYFPGWGGVRIE
                     DTVLITKNGPERLTKFPKDLMILDK"
     gene            44590..45189
                     /locus_tag="PC494_000841"
     CDS             44590..45189
                     /locus_tag="PC494_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3911363.1"
                     /translation="MYKKHKFIKNIKKAWYKIKLIDRCLIIVMAILMFQSIYNLFVNE
                     VNSQDTTTIDVVVRTTSAAIFGYFLSANFIKRPLRKYTNTDVSSNLFIDNNLSPKGQE
                     SNQNNIMNVKNTIGFTSEADNYEKKIPINNNEGFEEGETSELQIIIATVICIVALTVL
                     FVVRNFTTTTSASLGTISQMRDFVSGCVGFLLGCPSKPD"
     gene            complement(45375..46247)
                     /locus_tag="PC494_000842"
     CDS             complement(45375..46247)
                     /locus_tag="PC494_000842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDF3911364.1"
                     /translation="MNINYLYYFQTVCKYKNMTKAAESIHISQPSITLAIKELEKELG
                     FELFYRIGNKIELTPEGKIFLDKSKHFIKQFEDFQCDALDLGKKRKASLKIGIPTVLG
                     TFLLSKILPRFNVIYPDIELKIFEVPTFVGAKMIEESTLDFCIGIIDSDIYDDIDSKT
                     IYKTELYLVTNPKNELAKHPIISNYMLKNVPFVILSEGSYHYKIITKRLEKAKPNIIL
                     HSNQLSTIRYLLENDLASTILYKEIFQNTENLCSIPLERAITANIGVLWRRNQYISHS
                     MKLFIEYMASIHIN"
     gene            46664..48067
                     /locus_tag="PC494_000843"
     CDS             46664..48067
                     /locus_tag="PC494_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3911365.1"
                     /translation="MKGSDLVKFELMDFLMNPFVLMFAAVITGILFGKIKFGKFNFGV
                     SGALFTGLFIGWLAYSLGNLIIAKGETAAGYKAATVMMGNGIISSDFFDFFLIIFVAA
                     VGLLAAKDMKAVLKKYGARFVILGVLITFIGGSMTYAMTLLSSDKGSSAYEVSGVYTG
                     ALTSSPGLAAALETAGKHAEDVSKEFEKASIKDKKEILKVVDPEGKLDVNTTTSLTQE
                     QIDKYIAYAEAGVGIGHAVAYPFGVLIVILGVNFLPKLFRMDLKEERRKYEKEMKEAR
                     DSVSGKTIPEVPFNIITFFLTCLAGYLVGGIHVFMGPLGYFTLGATGGSLIVSLVLGY
                     IGKIGVVNFRMEEKVLNILKQIGLVFFLAIVGLRYGGKVVDSIMTSGMHLALVAIAVG
                     VTAMMIGFLVGKYVFKLNWILLSGAVCGGMTSTPGLGAAVDALDSDDPAAGYGATYPF
                     ALLTKVILVIVLHKLPM"
     gene            48094..49638
                     /locus_tag="PC494_000844"
     CDS             48094..49638
                     /locus_tag="PC494_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA hydrolase/transferase family protein"
                     /protein_id="HDF3911366.1"
                     /translation="MNNEGAFEELSGRLRNKELCDLIMNADEAAKIIEDGMVIGVSGF
                     TPSGYPKAVPLAVSERAKSGEKIKLTVYSGASLGPEVDGAWSEAGIIERRLPYQTNSI
                     LRNNINKGVVDYIDMHLSHSTQFLNYGTIPKVDVAIVEALAITEEGNIIPTSGIGNSP
                     SFIKSADKVIVEINLAKPMEMEGMADIYITENPPNRKPIEINHPKDRIGTTYIPCGLD
                     KIAGVVITNMQDKTRPLGVVDEASKKISNNIIAFLREEVKAGRLSKNLLPLQSGVGSV
                     ANAVLYGLCESEFENLTCYTEVVQDSMLDLIRMGKVTMASTTSVSPSPEGLIKFEKDI
                     DFFKDKIILRPQEISNNPEIARRIGVIAMNTAIEVDIYGNVNSTHIMGSKMMNGIGGS
                     GDFARNGAITIFSTESIAKNGDISSIVPMVSHVDHTEHDVMVIVTEQGYADLRGLAPR
                     ERAIKIIENCAHPDYKEQLRDYLNRACKSGAKQTPHILDEALSWHSKFMSTGTMKKAE
                     TFKSAL"
     gene            49669..51060
                     /locus_tag="PC494_000845"
     CDS             49669..51060
                     /locus_tag="PC494_000845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldehyde dehydrogenase family protein"
                     /protein_id="HDF3911367.1"
                     /translation="MEKAVENFEDLSKEYINGYIERARKAQREFECYTQEQVDKIVKI
                     VGKVVYYNAEYLAKLAVEETGMGVYEDKVAKNKSKAKVIYNNLKDKKSVGIIDIDRET
                     GITKVAKPVGVVAAITPCTNPIVTPMSNAMFALKGRNAIIITPHHKAIGCSTKTVEMI
                     NEELEKIGAPENLIQILDQQSRENTRNLISSADVVIATGGMGMVKAAYSSGKPALGVG
                     AGNVQCIIDRDVDIKEAVPKIIAGRIFDNGIICSGEQSVIVAEEMFDKIMDEFKNNKG
                     FIVRDKVQKEAFRNAMFVNKSMNKDAVGQSVHTIAKIAGVEIPEDTKIIVIEADGPGE
                     EDIIAKEKMCPVISAYKYKSFEEGVAIAKANLNVEGKGHSVSIHSNTVKNIEYAGENI
                     EVSRFVINQCCATSAGGSFFNGLAPTNTLGCGSWGNNSISENLDYKHLINISRIAYYM
                     PENEVPTDEELWG"
     gene            51253..52749
                     /gene="abfD"
                     /locus_tag="PC494_000846"
     CDS             51253..52749
                     /gene="abfD"
                     /locus_tag="PC494_000846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxybutyryl-CoA
                     dehydratase/vinylacetyl-CoA-Delta-isomerase"
                     /protein_id="HDF3911368.1"
                     /translation="MALMTGAQYIESLRKLNTKVYMFGEEVKNWVDHPMIRPSINCVA
                     ATYDLAHDPEYADLMTVTSNITGEKINRFGHLHQSVDDLIKKVKMQRLCGQKTASCFQ
                     RCVGMDAFNAVYSTTFECDKAHGTNYHDNFVKYLTYIQENDLVVDGAMTDPKGDRSLS
                     PSAQPDPDMFLHIVERREDGIIVRGAKAHQTGSINSHEHLIMPTISMTEADKDYAVSF
                     AVPSDAEGVFMIYGRQSCDTRKLEEGADVDLGNKEFGGQEALVVFDNVFVPNDRIFLC
                     GEWDFSGMLVERFAGYHRQSYGGCKVGVGDVIIGAAALAADYNGANKASHIKDKLIEM
                     THLNESLYCCGIACSSEGHKTEAGNYQIDLLLANVCKQNVTRFPYEIVRLAEDIAGGL
                     MVTMPSEKDFKSDLKVGTSGMTIGEVCNKYFKASSVASTEERMRILRFLENICLGSSA
                     VGYRTESMHGAGSPQAQRIMISRQGNINQKKELAKKIAGIKKEEALNL"
     gene            52884..53159
                     /locus_tag="PC494_000847"
     CDS             52884..53159
                     /locus_tag="PC494_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3911369.1"
                     /translation="MTCGVRFCGGCNPRYERGKALTIIKEHFNGRVDFSIAQENVEYD
                     LLLIIGGCATLCASYQQYKVKNECVKMWDFSHIERVINVIESAICET"
     gene            53183..54490
                     /locus_tag="PC494_000848"
     CDS             53183..54490
                     /locus_tag="PC494_000848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA hydrolase/transferase family protein"
                     /protein_id="HDF3911370.1"
                     /translation="MSWQELYQSKLCSATEAVKQIKNGDTVVFAHCVGEPPALVEAMI
                     ENAEQYKDVEIKHMVSLGSGGYTAKGMEAHFRVNPMFVSGNVRKAIENGDGDFTPAFF
                     HEVPKLLREKRLKCDVVLAQVTPPDEHGYCSLGTSVDYTYEAIKTARTVIVQVNDQFP
                     RTYGEVVHVSEFDYIVEKSQPLFELQPAKIGEVEEAIGKNCASLIEDGSTLQLGIGGI
                     PDAVMLFLTDKKDLGIHSEMISDGTLALYEKGVINGKYKNFDKEKMTVTFLMGTKKLY
                     DFANNNPAVEVKPVDYVNHPAIIMKQHKMVSINSAIQVDLMGQVVAEAMGLRQFSGVG
                     GQVDFIRGVSMGEDGKAIIAMPSITTKKDGTVISKIVSIVDEGAPITTSRNDVDYIVT
                     EYGIAELKGKSLRERARNLINIAHPSVRESLAVEFEKRFKEKY"
     gene            54510..55628
                     /locus_tag="PC494_000849"
     CDS             54510..55628
                     /locus_tag="PC494_000849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxybutyrate dehydrogenase"
                     /protein_id="HDF3911371.1"
                     /translation="MEALRVVPKIFYFDTFKEFNEEFKIGKNDLVITNEFIYEPYMKP
                     LGIDTNLIFQEKFGTGEPSDEMIDSMTKEMKKYNFDRIIAFGGGTIVDICKILALDVP
                     EKSIDLFEGEVSPKKVKELVVVPTTCGTGSEVTNVAIAELKSKHTKKGLAVEETYADY
                     AVLIPETVKGLPYKFFVTSSVDALIHAIESYLSPKASPFTEMYSLQAIKMIMDGYKKI
                     VDKGEEERFNHLRDFVLASNYAGIAFGNAGCAAVHALSYSIGGAFHVAHGEANYQFFT
                     EVFKMYSRKKPNGKIIKCTKILADALECDPNCDVYGELEKFLNKLIAKKALREYGMVE
                     SQIDEFTDSTIANQQRLLANNYVELSREEIREIFANLY"
     gene            55915..56835
                     /locus_tag="PC494_000850"
     CDS             55915..56835
                     /locus_tag="PC494_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-bromo-4-chloroindolyl phosphate hydrolysis
                     family protein"
                     /protein_id="HDF3911372.1"
                     /translation="MYKSENFSKKSVLINSFLSKFLKIIGWGLVSLFTLSALVLSTIS
                     IIIGWAVILPIQVCAVFLLIGGVCIFKGKRLGDQISRYKKYCTIINNRNIIPVELIAE
                     NTSKSLNFIIKDVQKMIDKNYFINTYIDKRNNQIVLTNEDFVPPRYEDVAYEVKEEEK
                     TDESNEVDTIINKGMNYLTQIKEANKNIKSESMGDKIVQVEDVTSKIFDVVKHDPSKL
                     TQIQKFMDYYLPTTLKLLNSYHTLEEQGIDRENITTTMESIENTMNTIVVAFENQLDY
                     LFEDEAIDISTDITVLENMLVQEGLTSGKF"
     gene            56950..58107
                     /locus_tag="PC494_000851"
     CDS             56950..58107
                     /locus_tag="PC494_000851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxic anion resistance protein"
                     /protein_id="HDF3911373.1"
                     /translation="MNNLDDIPVMPTLTLDPFGEESNTNDIDNSDLLMKKDEKDPEEE
                     KLSESERKMVKEFAEKIDITNTNMILQYGAGAQKKVASFSETALKSVKTRDLGEVGDM
                     LTNLVTDLKAFSADEKEQSGFLGIFKKANNKISNLKTKYDSAEVNVDKVSKELQKHQV
                     KILKDIAMLDKMYELNLAYSKELTMYIIAGKQKLKDMKEYEMPKLREKARLSGSTEDA
                     QSVNDMVSLCDRFEKKIHDLELTRMVSLQMAPQIRLVQNSNNLMAEKIQSTIVNTIPL
                     WKNQIVLALGISHLNQAMKAQREVSNMTNELLLKNAETLKMGTIETAKESERGIVDID
                     TIKKTNQSLISTIDEVVKIQHDGRIKRQEAEVELSKIENELKSKLLEFTVK"
     gene            complement(58192..59691)
                     /locus_tag="PC494_000852"
     CDS             complement(58192..59691)
                     /locus_tag="PC494_000852"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HDF3911374.1"
                     /translation="MAFYFDTPSHTFSEYLLVPGFSSTDCIPANVSLKTPVTKFKKGE
                     EADIYMNIPLTSAIMQSVSDDKMAIALAKEGGISFIYGSQTIENEAAMVARVKSHKAG
                     FVVSDSNIKPDNTLKDILDLKEKTGHSTVAVTEDGTSTGKLLGIVASRDYRISRMDLD
                     TKVSEFMTPMSSIVYANKDVTLKEANNIIWDHKLNSLPVLDDNGNLMYMVFRKDYSSH
                     KENPLELLDSSKRYVVGAGINTRDFAERVPALVEAGADVLCIDSSEGFSEWQKITLDF
                     IREKYGDTVKVGAGNVVDREGFLYLAEAGADFVKVGIGGGSICITREQKGIGRGQATS
                     IIEVAQARDEYFEKTGIYIPICSDGGIVYDHHITLALAMGADFIMLGRYFSRFDESPT
                     NKVNINGSYMKEYWGEGSARARNWQRYDLGGDKKLSFEEGVDSYVPYAGSLKDNVTLS
                     LSKVRSTMCNCGALSIPELQKNAKLTLVSSTSIVEGGAHDVMLKDNRNL"
     gene            60287..61711
                     /locus_tag="PC494_000853"
     CDS             60287..61711
                     /locus_tag="PC494_000853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol transporter subunit IICB"
                     /protein_id="HDF3911375.1"
                     /translation="MSSSNQSTIKTSIQRVGKFLSGMVMPNIGAFIAWGLITALFIPT
                     GWMPNEKLSTIGDPMIKYLLPLLIAYTGGKAIAGQRGGVIGAAAAMGVIVGADIPMFI
                     GAMIMGPFAGWVIKKFDKFVDGKIPTGFEMLVNNFSIGIIGMLLAILGFYAIGPAIVA
                     GTALIESGVQFIVSKSLLPLVSVFIEPGKVLFLNNAINHGILGPIGIAEAKEAGKSIM
                     FLLESNPGPGLGVLLAYWMFSRGSVKQSAPGAVIIHFFGGIHEIYFPYILMNPVLILA
                     TMAGGAAGILTFSILGAGLVAAPSPGSIFALMALAPKGGLLPVLAGVAVATVVSFLVA
                     APFVKRASANQSEEDSTSLEEAKAKMSDMKSASKNSEKNIEEKQLEVNEIKKIVFACD
                     AGMGSSAMGASRFKNRIKNLDLNIEITNSSVDNLPDDTQIVVTHNTLVERVAKNNSSV
                     EIVSINNFLNDPNLDTLFKRLESK"
     gene            61746..63875
                     /locus_tag="PC494_000854"
     CDS             61746..63875
                     /locus_tag="PC494_000854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HDF3911376.1"
                     /translation="MKKKKITSRQKKIILMIVENSKKNIPITISEIAGTLELSSRTVL
                     RDMSGIEKWFDENDFNFVKKPGVGLILEENIENQNFIIELLEEEKIEKEYSKEERNLI
                     ILSKLLVSNEPVKSYYFAKILKVSEGVLNNDFALASKWLERFDIELVRKPGLGVYLKG
                     QEKSFREAYVNLIYDSFNEKEILDMVRNISENIQTDKAIEILSENRLLNLMDRCIIRK
                     VEATLTKKLSDLDVNLADSAYIGLVVHISLALQRIKNGENITMDKEFLKELSITEEFK
                     LAKEIVKGMETDFNMDIPVDEVGYITMHIRGAKQRSSSNHKALNLDDIEIMEITNKMI
                     DLAEDEFKISLKNDERLFKDLANHLGPSINRLNMGLEIRNPLLDEIKSKYSYAYDGVE
                     KISRIIKDKLNINSIPESEIGYIAMHFASAIEKNLMMNTNINIVVACPTGIGTSRFLS
                     TKIENKFPNLNILETISAINIDEEYLKEKDVDLIVSTVELNTSLNYICVGPFMSLDDE
                     QIIKEKIKSIAQNKLINLNAKNDTKSKNKVYEQITESMNIGKDILQFLEEIRFEKFES
                     KDLSELIEDSSKIFAKSSEDIISIKESLKERLKISIPYIEESKILLLHCMSERIDIMK
                     LSIIKLENRIVLDSNEEIDNVVFMLLPKNSPSYQRQIMSEISGSLIDNIIFTNKINKF
                     SIEEMALEVKDIVFNFYTNRLKAFIDK"
     gene            63905..64327
                     /locus_tag="PC494_000855"
     CDS             63905..64327
                     /locus_tag="PC494_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDF3911377.1"
                     /translation="MSKVLNENNIFLGLDSVSKEEAITLAGRKLVENGYVKEEYIPAM
                     LEREKVMTTYMGMGVAIPHGVNEAKKEILSSGIVILQFPNGIDFDGEKAYLLIGIAGV
                     GDEHLEILSNIAVVLDDDLTERLKNSNDKQAFMEAFAN"
     gene            64346..65497
                     /locus_tag="PC494_000856"
     CDS             64346..65497
                     /locus_tag="PC494_000856"
                     /EC_number="1.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HDF3911378.1"
                     /translation="MKKAIQFGAGNIGRGFIGGLLVKSGYHVVFADVNEGILNSINKD
                     KKYTIHIRDVECIDEVIDNISAVSSIKEEIIDEIVQAEIITTAVGPLVLTKIASTIAK
                     GIKARKEKGLTSNLNIIACENAIYASSSLKEEVLKYLNKEEVEYLEMYVGFPNCSVDR
                     IVPPGKNENPLDVTVENFYEWNVEKQGFKGEIPTIVGMNLADNLMAYIERKLFTLNTG
                     HAITAYIGYLKGYKTIEESIKDKFICDIVKSAMVESGEGLIKKYNFDSEVHYKYIDKI
                     LNRFKNPYLNDDVLRVGREPLRKLSDKDRLIKPLMTAKSYGLSVDNLILGIGAALHYN
                     NSEDTQSVELQELIKSIGVKKAVAKIANISNDEELLNNIEKSYIFMKNL"
     regulatory      65603..65704
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            65887..66459
                     /locus_tag="PC494_000857"
     CDS             65887..66459
                     /locus_tag="PC494_000857"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HDF3911379.1"
                     /translation="MKALQEKILREGSVSGNDILKVDSFLNHQIDVAFLNEIGREFKE
                     RFKGEKVDKIFTIEASGIAIASIVSQYFDNAPVVFAKKSESKNLDKDVYETNVYSFTK
                     AREYSVKVSKKYINKGENILIVDDFLANGRAALGLKDLIEQAEANLVGVGIVIEKGFQ
                     AGGALLKANDVRLESLAVVESIDNGTVKFR"
     gene            66523..67173
                     /gene="fsa"
                     /locus_tag="PC494_000858"
     CDS             66523..67173
                     /gene="fsa"
                     /locus_tag="PC494_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HDF3911380.1"
                     /translation="MRFFIDTANIEEIKEANDLGVICGVTTNPSLIAKEGRDFIEVVK
                     EISEIVDGPISAEVISLEHKGMIEEAEKLSKIHKNIVIKIPMTAEGLKAVKVLSSKGI
                     KTNVTLIFSAGQALLAARAGATYVSPFVGRLDDISQNGLDLIEEIVDIFSVNSIEAQI
                     IVASVRNPIHVLQAARMGADIATVPLKVINQMIKHPLTDKGIDSFMKDWEGASLKL"
     gene            67325..70249
                     /locus_tag="PC494_000859"
     CDS             67325..70249
                     /locus_tag="PC494_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDF3911381.1"
                     /translation="MDKILREIQREDKKNPYTDQELAEMLNVARSEVISVRKKNNILD
                     SRERRKKILIKDISKIVSENPQMSERKITEILIENGYNISRSAVSKLLKEENLNQSKI
                     GIKDKDPASSGKYVKVSKVVEEDGFEELIGIKGSLKEKVNLAKSAIMYPPNGLHTIIY
                     GETGVGKSELATCMYKYAIKNNIKEENSPFIVFNCADYAENPNLLIAQLFGVVKGAYT
                     GADANREGLVEQANNGILFLDEIHRLPAAGQEILFSLIDRGEFRRLGESSSNRKANVL
                     IISATTENPDSNLLQTFRRRIPMVINLPNMSERPKSERYEIIIKFFEREAKRVNKNFI
                     ITKEVMCALMNYKCTGNIGQLKSDIQVTCARAFSKSIFSSDKVIIDLDSLRDYIKSGY
                     YDCNCKNEKYSEFSVEDIYIDISELVSGKNRILSDNEISEIYNYAEKELKVLESKCFS
                     EEELKNAFIEKLDKKFNAIKNNKNLSDRRSRIDWGGQLKESTLEIMDKVIVFIKEQFK
                     HVNQGLYLALAIHIEHAIGRIKDGKTIINPSLDKIKASMPMEYELSRYIMGIVEDLTQ
                     VTFPEDELGYLAYYINKFCYNEESIKDKVKVVIVTHGKVGIEMSKVVNHILGIECTLG
                     IEIALTDSPSEGIEHVLEELQKIEARKGILVLIDMGSLVILGDEVEKRLGIRCKTVNR
                     VDTLLAMEAGKLATIEGKSLDGIIADLKKNKNYAMINTNKFSYRKNEYGKKNVIITLC
                     LSGVGTALNLKEHIEKQIKEYDTLIEVKPVAFLNNNLEEELNDIEAEYNIIAICGTID
                     IDYKNVPFISYNEVLGKNGINKVLEHLNSKQPALNIENQLNNLIHEDLILYNFEGISK
                     EYIIDTLVSKLEEGGYVDSKYILSVYKREAMGSVVMASKVAVPHGLPENVIKPAIAIA
                     RLNKPIVWDNKFMVDLVVLLALKENNKKEIRSLFSKINDQHTLEVLLNTEDKNEIKEL
                     LS"
BASE COUNT        27776 a         7618 c        12693 g        22342 t
ORIGIN      
        1 ggttattaaa atttattaga tattactcta gtttatttta aaaaaaagta ttataatatt
       61 ccttgtgtga aaatatagga atttttatta aatagtttta atgtgtaaat aacattctac
      121 actattgtaa ttaaatatgt aaaaagtaaa atatttaaat agatatattt taaaatctaa
      181 cttttaatat tgtaaaaaaa ttagaaattt aacaaaaagt acaaaaattc acattttttt
      241 cataaagtgt ttgactaaaa aattcacatg ttgtagaatt aaggtagcag gagttttgag
      301 ggaggtgtaa ataatgataa gaaaaatacc acaagcagaa ctaaaagtaa tgaaattcat
      361 ttggaaagta gatgttacag tgacatcaaa agatgttatt gaagctatgg aacaaaaata
      421 tggctggaaa caaaccacca cactgacact tttatctagg ctggtaaaaa gaggattctt
      481 agatgctcaa aaaatagaca gatatacaca ttacacaata agagtaaaac acaaagatta
      541 tttaagtttt gagacaaagg atttcctaag taatatacat gatgactctt taagaagctt
      601 aatttcagca ttacatgatg atgaaaatat aggtaaagat aagctagatt ttctagaaag
      661 ttattttgat aatttaaagg atgaataatt atatgctata tgtttttgaa aatcttataa
      721 agacaactat tgtatgtagt cttggtattt gtctattatt atttttgaaa agatatttat
      781 ttaagaagtt tagtaagaga ttcaattatt atatttggtt gataatagtc tttagaatgt
      841 tactttttct atttaattat acaatagtgt atgaagtaaa agaacccaaa gaaaatgcat
      901 taggaaataa tattacacaa attgatattt ctacagataa taatcttatg ctgtatgtag
      961 cttatttatg gttatttgta actatagtca ttgcagttta tacatttata aagtatacaa
     1021 gatttaaaaa tctagttgtt gatgtatctt atgatattga agataatgat ataaactgta
     1081 tctacaaaaa cttgttaaaa gaattaaata taaaaaagaa aattgaatta agaggttctg
     1141 atgaattgat aagtccagca ggtatgggat tatttaaatc ttacatattc ttaccagact
     1201 atccttatag taaagatgaa ctaacttgga ttttgaaaca tgaattaatg cattttaaaa
     1261 ataaagatat tttaataaag tttttagttt tgtctgttag aataatatat tggtttaatc
     1321 cacttgtata tgtaatgagc aataaagtaa atctagattg tgaattatgt tgtgatgaaa
     1381 gtgttttggt agaatgttct ttaaaagata aaaaagaata tgcactagca cttataaagt
     1441 taattaagtt tagtaaaaat tataatagta agattttgac aaccgagttt gataagacaa
     1501 atttggaaaa gagacttgag agtattgtta aaaagaaagg caaaagtgga atactaattg
     1561 ctgttttagt atttatgact tctataacat cttttgttga agttgatgct caagttagaa
     1621 ttgatgaggg taataatgga atgaataaca atattaatga atttttattg aataagacga
     1681 ctgataaaat tataaatatt tattataaag atgcaccaaa tgaaattagg aaattttatg
     1741 aagataaatg cgaattagaa ggtaaaatac ctagagacta tgacataata gaaatggata
     1801 tgaaagatta taatcaatta ataaaataat tataaggagg attttatgtt aacaaaatta
     1861 agaaaaatag tagctattat gtgttgctta ttgcttactt ttacaagtgt ggcatttgct
     1921 gacacaagta aagagaaagg aggaagtaaa gagactgttc cagagaaaaa cctagattct
     1981 tttactcttt ctgggtatat atatacatat gaaaatgcgc cacaagaaat aagagatgaa
     2041 cataaacaaa attgtgaaga gataaatata gaccctaagc cagatgatga gatatttgtt
     2101 ccagaatcag ctaatctaat gaatgaggac aatagtaaag gtgtttatgc aagttatact
     2161 gtttcttata atataggtgc taaaactata acaattatga gtaatgagta tttgactata
     2221 agtacaacaa aagttatacg aaagggtaat agcggaaaag aagtaaaagc tgcacaaatc
     2281 atgttaactt tacttggtta taatgtaggt atagatagtt cttttggaag taagacatat
     2341 aatgcagttg taagtttcca aaaaaaatac ggtttgtctg cagatggaat aattggtcca
     2401 gctacttggg ataaattggg tagactaact gaccctactc tttcatagga ttaaaatcta
     2461 aaaatatatt aaatagtgtc tcaatatgat ttttcaattt aaatgagaca ctatttaaat
     2521 ataaatgtta taaaactatt ttacaataaa ttccatataa ctctaccatc tatatcctta
     2581 acattttgac aaccagtcaa aatcatagtc tcacataact cattcctaac cttctctata
     2641 aaaaactcca caccatcaag accaccgcca aaagaagcag taacaaaagg tcttcccatc
     2701 aaaacagcat cagcacccaa tccaagcatc ttaactacat caacaccagt cctaactcca
     2761 ccatcaacaa gtattgttat ctttcccttt acagacttag ctatatctgg aagtacctca
     2821 caagtaccag gagtataatc aagtactctt ccaccatgat ttgaaacaat aatggcacta
     2881 gcaccagact ctacagccat caaagcatca tctacagtca taattccttt tataataaaa
     2941 ggtaatctag tggattcaac caattctcta atctcatcaa ttgttttagg agaaaaagga
     3001 ttttcttgaa attgattatt aataagtcca caagcatcaa ggtctacacc aactgcaaaa
     3061 gcacctgctt cttcagacaa tctaatttta tctattatct ttgaattatt ccaaggcttt
     3121 ataaatacaa ttccatttcc cctattatcc ttcaatacat ctaaattatc cagtaaaaaa
     3181 gtatctacat tagtatcgcc aaccatagca taaattccag aattagaaca acctctaaca
     3241 acaggctcta tgtattcttt ttcggaaact ttaccaccca tgttcaatat agtacctgat
     3301 acaggtgcag cgaatatagg agaactcatt tttctaccaa ataattctat ggatgtatct
     3361 ggctttgaaa cattatgtat gactctcata tttatcttta ttttttctag actttttcta
     3421 ttttcaatga aagacgaacc acttccttta ccacccatac caggaacatc tccagcacaa
     3481 gctaatccat tacaaatttt acatacttta catgttccat taaagttctc tctagctgat
     3541 tttagtaagt cattgtaatc catacaaaat ctctcctttt tataatatta aaattgagta
     3601 ttactatatt gaaaatatct taattgtaaa tatagggatg ttattatgat gagctaaact
     3661 agataataca tattagatat tttttattgt tgtagatagt taaattatat catattagat
     3721 agtcaaattt tgaaaaaaac taacttattt aagtatacat tttgaaaaaa ttaaaaaagc
     3781 tatatataga tttttaaaga aatctatata tagcttttaa gtttatgtca atcttttttg
     3841 ttaatgaata aataatatag aatacaatat acaaaaaagt ttcttgaaat gctaagataa
     3901 tccccattta caaagcaaca tcattatact gtgtaaattt gaatcaacaa tgttttcacc
     3961 atatttcatc ataaaatcct ctaattgtgt gtcaataaat gaataatatc cacttatact
     4021 atcgatgtat gcagtcatta agtgtataca ttcatcactt ttatctttat acatatatat
     4081 ctccccctat atacaatata taaatttaga taccaaatcg tatcatatta aatagttaag
     4141 tgtgtaacat ctatgcagtt atatatttat atcattatat taataactaa agtgagtttt
     4201 gacaatagat tttgggaaac tggatgttca aagtgcaaac ttggatttta aaatcattaa
     4261 ttaagatagc gcataggaat atatgtatac ataacttaat tataaagatt ataaacaatt
     4321 acttttatta actttattta aatggtagaa taacttggag attaataatt ataaggagga
     4381 tataatatga gtttatataa gtttatatat gatgataagg aatatttatt aaaagaggag
     4441 aactgtagtg ctttaataaa tgatgaagaa aatccagttc aaggagtaag tatttcaaaa
     4501 ataattgata tacttaatga agcagaagaa gttgattttg atgtagaata ttatcaagaa
     4561 gcatgtccat tatgtttaga aggagtaaaa gaaaagaaaa aattctttcc ttttttagaa
     4621 tatcactttt atattttcag taaagatgga gaatatgtaa taagcaatat atctgttgat
     4681 tataaaggac tatcttttaa taaactatca agggcaaata aagttgataa tagttatatt
     4741 gtaagtgtga taatttgcga aaattgtcag gattatatag ttcagataga aaattgtata
     4801 gtttagtgta aagtatgtct taatttaaga gaaatttcta aattgagaca tcaacttttt
     4861 tcaaaaatag tatggaaaat tactaaattt atgagataat gtaagtcgga ggtgagttac
     4921 aatatatagt aaatatttgg aagagataga tgatacaatt ttagattcaa tgtttaaact
     4981 aaccttgaat gaaagattat tgactaataa cgattttatt gaaaataaaa ttgatgtagt
     5041 aaagaattta attgattgct ataaaactga acaaaatagt ttaatgttat taaaatcaaa
     5101 ttttttgcta gctttattat atggtattca agggtttagt gaaaaaatga aagagtatat
     5161 tttgatttcc tgtaaatata ttgataaatg cttacccaaa gattataaat ttttagcacg
     5221 attttattca caaatagcta ttttaagttt aaaaaatgaa gatgtaaata aggcaaattt
     5281 atatatggat aaatttaatc ttatttgtga tgaaaataat tttctaattg aagaaattat
     5341 ttttaaatca caacttattt acattaaggc aagtaagtgt atagaatctt ctgtaataat
     5401 taaagagata gaaacgttgt atataaagat aaaagaaatt aacgatttta attgtaaaaa
     5461 aatatatttt tttattattg gtaaaatata ttttttgttt ttggatgatg ctctaattgc
     5521 taaggtaaat tttttaaaag caagaaaata tgcagattta ctaaaggata tgcaagtatc
     5581 ttcactatgt aatataaaga taggtgagtg tgaatgttcg tttgaaaatt atgaatgttc
     5641 catggaatat ttcaatgaag taataagcaa taaaaagtat agaaatgtaa atataattca
     5701 aaaatataga gcatcaaaca acataactaa aatattaata aagactagaa attatcctgt
     5761 cgcaataaat aatttagcaa aatctgaagt atatctagaa aaaattaaaa atcatagctt
     5821 aaaagaagta gagaagtttg atttatttat aagtttagcc atgtattatg caaaaagtaa
     5881 tgaaaaatct tttgaacaat caatatgcta tttagataga gctaaaaaca tattaaatat
     5941 gataaaaaat atagaagaat atataatata tgatttagaa ataatttatc accaggcaaa
     6001 gatatattat atctttggat attatgataa tgccttaaac acaaataaaa aactccttga
     6061 aaaatctaaa aatgctaaaa attataatta tgtgaagtta gcatacaaga gtatatattt
     6121 gtgttttgaa aagattcaaa attatgaaat gagtatgaaa tactttaaaa tgtattatga
     6181 gttaaaaatg atgtatataa aagctcgaaa tagaaattat atagattcct taaattatag
     6241 acatgagtat atagaaaaag aaataaataa catgagaaaa gtaaaacttg atttagataa
     6301 aaaaaagtat gttgaccatt tgacaagtgc atataataga acttttttga acgatttttt
     6361 agaaaaacaa gaagttagtg aatattgcac agcatttatg atagatgtag attactttaa
     6421 agaatacaat gatacttatg gacactataa tggagatatt gctcttaaaa atataactat
     6481 aataataaaa aaatatctaa aaaaagacat gcttatgata aggtatggtg gagaagaatt
     6541 tctgatatta tctgtatgta aagattataa aaaaagtaaa atatttggaa gaaaattatg
     6601 taggattgta aagaaatttt taaacaataa tttgacagtt agtattggca ttgatacatg
     6661 taaaaatagt agtatagata taaaagaaat aattgaaaat gctgataaag ctttatataa
     6721 agcaaaggaa agtggtagaa atagatgttt gcattatcat gattttaaga atttttaact
     6781 gttgaaatag gattggtgat ttacttgaaa aggagtttaa tagaagattt aaagagaaat
     6841 ataaacaaga tagaatacga tatgttgact aaattctatc taaatttgac agatttaaac
     6901 tacatcttgg attatcacaa agacctttta aatacaaaat tagaagataa tagtagagtc
     6961 tatactttat atttaattag tcttataaac tatataaaaa aagatagaga agcatcatac
     7021 aactatttga tagagtcatt aaagtatatt aaaaaattgt cattaaaaga tgattcagat
     7081 ataatatcta aaatttatat ttatcttact ttatcagcta tttctataag aaaatatgat
     7141 aaggtaaata atttttattt ctcagcaaaa aaaattataa gacaaaatca tttaaatgag
     7201 ttgttggtat tgttaaatat gagtttatgt gtagaaataa gtgctttata tcagaccaaa
     7261 acggatgtaa tagctttagt agaagaagtg tcttttttta aaactttaaa aaataaagct
     7321 cttgtaagta gggcaaatta tatatttggg agagtttatc tatatttatt taataacttt
     7381 ataaaaagta tggaatactt aattgaatgt ctaaaattgg ctcaagaaaa taatttatac
     7441 tctatagagg ctttttgtaa atgtataata agtttgtgtt atttagagag tggaaataat
     7501 gtagaagcta taaaatacat aaataatgta ttagatgttg cacacagtaa taactcaata
     7561 tcagtaactg aaagagtgtc tataaaaata gaccttatat gggcatattt aaaagaagat
     7621 atgaataaag aagcagaagt tattttatta aagactataa aattaatgaa agttgttgaa
     7681 ggtgtatata aggattattt atattcattt atatttttat attcagctga aattgagtta
     7741 aagaaagata attgtagttt tgaaaaggta aacacctatt taattttatc aaaaaatata
     7801 tataaaagtt ttggagatgt ttttatatat aattctaaac tagattacat atataagttg
     7861 tatggagatt tatatataaa atttggtaat atagatgaag gtataagttg ttatataaaa
     7921 ggtttaaatt tagttaaaaa gagttcattg aatcttagaa aaatatctat attttatggg
     7981 ctaatagcaa atggatatga gctaaaaaaa gattttaaac tggcaataga atattataaa
     8041 agtatggatt ggtattctga taggtgggaa aaaaataatt cctataaaac atctcaagca
     8101 attcacaaac aatatgaact cagacaaaaa caagagagtt taagattact agtggatgat
     8161 aataagaaat tagaaaatga tattttaaaa gatggactta ctaaactata taatagaaga
     8221 tatctggaac agcagttgga tttatttaat gaaaccagag acaaaaatat ggtcgcaata
     8281 ctggtcgata tagattgttt taaaagttat aatgataatt atggtcatct agcaggagat
     8341 aaagttatag ttaaggtaac tgatattata agaagtgtat ttatagatat taccgaacac
     8401 ataatcagat atgggggaga agaaatttta atattagtag attctataga atcaatcggt
     8461 gttgaagaga ttgataatat agaattatat attaaaagag ttttcaaact tcttgaattt
     8521 gagggtattg aacatatata ttctaaaata aaaaactata taactataag tgctggagta
     8581 agtataaaaa gatgtcgtag tagaaaagat gttgaaatat taattgaaga tgcagataag
     8641 aacctatata aatcaaaaaa agcaggtaga aatcaataca ttataattta aaattgaggt
     8701 gattttgttg cgaaaaaaaa taggaattat agcctctgat attgaattaa aagaaagaat
     8761 agaagaatta tatagagaag atgtagaaaa tggaactata ataatcgaca tacttaacct
     8821 agacttaatg gaaaatcaag gtcgtatact tgttgaaaaa ggtgcccaag ctataattgg
     8881 tagaggtgga ggttatagtt tagtaataga tacagtaaat gtacctgtta taccaatgaa
     8941 tatgaagtca actgaccttt taagagcaat agaaatagca aagaaatatt ctaaaaaagt
     9001 agtattgatt cttggagaca atgaagtttc ttttgactat gttggctgga gaaatgtcat
     9061 aagtactgaa ataactgaag aatggtttga atctaagtat gagataagaa gtaaagttgt
     9121 aaaatatata gaccaaaaag atgaaattgt aatcgtagga ggaggtttgg catgttcttt
     9181 tgcaaggcaa tatggaattg atagtgtatt tgcaactgct agtgatgaat ctataagaga
     9241 agctgtagaa tattgtaaaa aattattaga tacattaggt gaagaaaagt ttaataatga
     9301 agtgttacga aatatacttg atggtataaa agatggagta attgctatag atagtaatgg
     9361 cagtataatt ttgtacaatg aaagtgcaaa aaacatgctt aaagtagaga gaaaatgtgc
     9421 acttaataaa tacatcttag atgtatttcc taaaatggag tggatgttag attgtttaca
     9481 tgaaaaagag gacgtagaag atagaaagat aagaaatata aataatctaa ttgttaatac
     9541 taggacaaca ttgataaaag ttgataatag tacttatgga gttttaggaa taatacaaga
     9601 tataaccaag ctacaaaact tagaaagaaa aataagattt gacttgaatc aaaaaggtct
     9661 ctatgctaga tatacttttg atgatttttt atttaaagat aaattaacta aagaatttat
     9721 tgaagaagct aaaaaaattg gaaaaagtga ttatacaact ttactttatg gggaaagtgg
     9781 gtctggtaaa gaaattatag ctcatagtat acacaatata agtaaaagaa aagataggcc
     9841 ttttgttgct ataaattgtg ctactatagc agaaaattta cttgaaagtg aactttttgg
     9901 ctatgaagaa ggtgcattta ctggtgctag aaagggtgga aaaagagggc tatttgaact
     9961 tgctcatgga gggactcttt ttttagatga aataaatagt ctatccttta atattcagac
    10021 aaaactatta agagtaatag aggaacgtca aataatgaga attggttctg attatataat
    10081 acctctggat ataaggatta tagcagcaac gaacgaatct ttaaccgaaa aaatagttat
    10141 gggtacattt agagcagact tattttatag attgagtagt ttagagataa atatacctcc
    10201 tttaagagac agaagagaag atataatacc tttgtttaac aattttgtaa atgaagtatt
    10261 aaaggatgat ggtctcaatg gaataaacag tatagatgaa aattttgttt tgactaaaga
    10321 tgaaatggat aagctatata attatagctg gcctggaaat gtaagagagt taaagacaat
    10381 agctcaaaaa tatgttgtga caggtaaaat taaattgaga caagatagag attttaaaac
    10441 taaaaaatta cttcctaact ctgaagtaga caaatttaat tctgaaacga cagcaagtgt
    10501 agaagtccaa gatgaatcta taaatataag taagataaat gatggtaaga taagtataga
    10561 tataaaagaa gtaaataagt atgttgaaga aaaaataata agtatgcttt ttgctcaagg
    10621 actttctaaa aatgaagttg cacaagttct tggaataagc aggacatctt tatggaagaa
    10681 atacaataaa aatatttaaa tataattaca tataaattat tttgaagtaa tgttaatttt
    10741 ttaaaacaag tgttaagaaa aattaacatt acttttttgc aaatttttat ttttttagac
    10801 aggcatatat atttataaga aaaatagtta aaacacttaa tttaataatg aaaaaaataa
    10861 taattctaaa caaaatcaat tttacataaa gtgggattta ttggcatagt aattgcttaa
    10921 tatataatgt aagagtaaat acaattttag gggtgatggt atgagtcaaa gtatggttgg
    10981 taagcatgca atgtggccaa aagaaaatga tgttatattt agcatatctg gcagagctca
    11041 agcagcagag aaggcttttg gtatggataa tgtaataaat gcaacaatag gcgctctaat
    11101 ggatgattca ggaaaattga taacaatgaa aactgtatat gaagaatata aagcattaga
    11161 taactgtgag ataggtgcat atgcagctct tgaaggtcaa ccagattact tagaagcagt
    11221 taaaaaagta tttttcagag attacttacc agaaggacat ataagagtat tagcttcacc
    11281 aggaggaagt ggtgcaataa aattagctgt atggaactat actaatgaag gagatgaggt
    11341 attaacatct gattggttct ggagtccata tgtaagtata gctgaagagg ctaatagaaa
    11401 agtagttaat taccaacttt ttgatgaaaa tagaaggttt aattttgagt cgtttaaaga
    11461 aaaatttgta aatatagcag aaaaacaagg tagagtcttt acaattataa acacaccagc
    11521 gcataatcca actggatata gtgttgcaga tgatgagtgg gataaaatat tagacttatc
    11581 aaaagaagtc gcaaaagata aagacaaaaa gataatattt ttcgtagatt cagcatatat
    11641 tgactttgca ggtgatgatg atgtatgtag aaagtttttt aagaaatttt ctaatttgcc
    11701 tgaaaacgtt ctcgtattgg ttggattcag tatgtcaaaa ggatttacag cttatggtat
    11761 gagaatgggg gctataattt gtatatcttc aagtgaagat gtagctgaag agttccatta
    11821 ctcatgtgtt cattcatgta gagcaaattg gtcaaattgt aatagaagtg ccatggcagt
    11881 attatctaac attgtaaatg accctaaaaa attcaaagaa tatgaggatg aaaaagaaat
    11941 atacaaaaac atgcttacta gaagagcaga tgtatttgta aaagaagctg aaagagtagg
    12001 attagaaatt cttccatata tagcaggttt ctttgtaagt ataccatgtg ataatccaaa
    12061 agaagtatgt gaagaattga ctaaacataa tttatttgca gttccattaa aaatgggttt
    12121 aagatttgca gtttgtgcag tttctgaaga taaatgtaag aaagcaccaa gtattataaa
    12181 agaagcactt gaaagtttag aagtaaaaat aaataattaa tttcattgaa caaattgggt
    12241 ggactatgaa tttaataatt gtagatggag ggaattttat atgaaacaat tgatgacagg
    12301 taatgaagca attgcacgtg gagcctatga ggctggtgtt aaatatgcat ctgcatatcc
    12361 agggactcca agtacagaaa tattagaaaa tatagcaaca tataaagatg caatagttgc
    12421 agagtgggct ccaaacgaaa aggtagcact tgaggctgct atagggggtt caattgcagg
    12481 agcaagaaca atggcttcta tgaaacatgt tggtttgaat gttgcagctg atccaatatt
    12541 tacttatgca tatacagggg taaatggtgg tatggtactt attacagcag atgagccggg
    12601 aatgcattca tctcaaaatg agcaagacaa taggatgtat gcaaaatttg caaagatacc
    12661 tttatttgag ccatcaacta gtcaagaagc taaagatatg ataaaagaag cttttgaagt
    12721 tagtgaaaaa tacgatacac cagttttata tagagttaca acaagacttt gtcattcaaa
    12781 aggattagtg gagtgctatg atagagaaga agttgaaatt aaagagtatg ttaaaaatgc
    12841 taagaaaatg gtaactgttc cagcaaatgc tcaaataaga aggggcgttg ttgaagaaag
    12901 aatggaaatt cttaaaaaat tctcaaatga aactgattta aactactatg aaataaatga
    12961 tacaaaaata ggtgttatag cctctggtat gtgctgtaat tttgccaaag aagtttttgg
    13021 aaaaaatgca tcatatatga aactaggatt tacaaatcca ttaccttatg aaaaaataaa
    13081 agaatttgca gaaaaagttg ataaaatata tgttatagaa gaaaatgacc catttataga
    13141 agaacaaata aaagcatatg gaatagattg tattggaaaa gatgtaatac caccatatgg
    13201 agaaatgaca ccagatgttt taagaaaagc tatatttgga aaaacaaatg atactataga
    13261 atacaaatct gaattagtaa caccaagacc accaagtttc tgtgcaggat gtccacatag
    13321 aggattcttc tatgaacttg gaaagagaaa aaatttaata gttggtggag atataggttg
    13381 ttatactctt ggatttgctc ctccatataa tggaatagat tatgttgttt gtatgggttc
    13441 tgcttttgga actgcacatg gagctcaaaa agttcttaat atgaaggatg ataatgaaaa
    13501 aagattggta ggtgtacttg gagactcaac attcttccat acaggaataa atggactttt
    13561 agatgttgtt tacaatagag gtaattctat ttcggttata ttagataata gaataactgg
    13621 aatgacaggt caccaagaaa acccaggttc aggatatact ttacaaggtg ctaaaactaa
    13681 agaagttgat atagaaggat tagttaaagc ttgtggaata gaacatgtaa gagttataaa
    13741 ccctaataat ttaaaagaag taaatgaagc actagattgg gctttagcta tagaagatga
    13801 accatcagta ataataacaa gatggccatg tgtacttaaa aaattctcta aagaagatat
    13861 agaagaattt aataatccat ttaagactaa gtgtaaagtt gaccatgata aatgtatagg
    13921 atgtaaatta tgtttgaaaa ctggatgtcc agctctatca tttgataaag agaataagtt
    13981 atcaaatata gatagaaatc agtgtgtagg atgtggagta tgtgcacaag tttgtccaaa
    14041 acaagcaata gttaaggagg aaaaataata tgactaagag tatacttttg gtaggtgtag
    14101 gaggtcaagg aactatactt gctagtaaat tattaactat gggattgatg gaagctggat
    14161 atgatgtaaa gatgagtgaa atacatggaa tgagtcaaag aggaggttca gtttcctcac
    14221 aagttagata tggagattgt gttcattctc cagttataga aattggtgga gcagatatat
    14281 tagtatcttt tgaaaaaatg gaagctttaa gatggttcaa ttatttaaaa ccagaaggaa
    14341 aagctttagt aaataatcat aggatagatt ctatgactgt tttaatcgga ggagctgaat
    14401 atcaagaaag tgatatagat gcagagttaa gtagattaaa tgcaaaagtt ataaatgcag
    14461 ctgataaagc tgaagaacta ggaaattcaa aaataatgaa tgttatttta ttaggatgtc
    14521 tagttaaatc tatgcaatta gagtctattg attgggaaaa aattataagt gaaaatgtta
    14581 aaccaaaatt tgttgaatta aacataaaag ctttccatga aggtatggaa atggttagca
    14641 aatagtttat aatagatata aatagactat agaaattaag gtgaaaggaa gaaaattatg
    14701 acttacagaa tattagccat aaatccaggt tctacttcta caaaaatagc agtatatgat
    14761 ggagaagaac aaattcttgt gaagacgata gaccatccag ctgaagagat tgcaaaatat
    14821 aatactatac aagaccagtt tgaaatgcgt aaggaagcag ttttgaatat tcttaaagaa
    14881 aatagtatag acttaaaatc tcttagtgca atagtaggaa gaggtggagt tttaccacca
    14941 gtaaaatcag gagcatattt agtaaatgaa gaaatgattg atgtactaag acatagacca
    15001 gtacttgaac acgcttccaa tttaggtgct gttgtggcac atgcaatatc agaacctctt
    15061 ggaatcaact catatattta tgattctgtt gcagtagatg agcttataga tgtagcgaga
    15121 atatctggac tttgtggaat ggatagatca agtgcagggc atgcattaaa tactagagca
    15181 atggctttaa aatatgctaa ggataaagga aaagattata agagcttaaa cttaatagta
    15241 gctcacattg gtggaggagt aagtatttat cttcatgaaa aaggaagaat ggttgatatg
    15301 ctatctgatg atgaaggacc attttctcca gaaaggtcag gaagagtacc tgctacaaaa
    15361 ttagtggctg cctgttattc aggtcaatat tcagaaagag aaatgactaa aaagataaga
    15421 ggtaaaggtg gtatagtttc atacctaaat actgtagatg ctagagaagt tgaaaaaatg
    15481 atagcagaag gaaatgaaga agcaaaaatt atttatgaag caatggctta tcagttagca
    15541 aaaggtattg gagagttagc aactgtagta gatggaaagg tagatgctat aattataaca
    15601 ggtggaattg catattctga aatgtttact tcaatggtta aaaagaaagt tgagtttata
    15661 gcaccagtag aaattatggc aggagaaaat gagttggaat cacttgcttt tggaacttta
    15721 agagtactaa atggagaaga agaagctaga atttatagtg aaaattaata agaaaaacta
    15781 aaaatgttta tatactaaaa aagtggtata tccgtttttt atacacgaaa gcttagagta
    15841 taggtgaaaa tgtataaaat ttggattgcc actttttata attaaaattt tatcttaacc
    15901 taataaataa ttctgtaaaa tttcgtattt atatatatat tttattggta tttattgtta
    15961 ttattattat gaggagtgat ttttgatggg aaaaataagt ttaaaaagta tgataagatt
    16021 attttcaggt ttttttatat ttgcaatttc ttctgtgctt atgattaatg cacatgtagg
    16081 tcttatgcct tgggatgtac ttcaccaagg tttatctata aagctaggca taactatagg
    16141 tcaggcttct ataatggtag gagttgtaat tgttatattg gatgcagttt ttggtgaaaa
    16201 tataggatgg ggtactttac tcaacatgac atttatagga atttttattg atttagtaat
    16261 attttctgga gtgatacctc atgcaagcaa cacttatata ggtgtgttta tggttgttat
    16321 aggaattatt ttggcagcta tagcaagttt tctatactta ggtgtttgtt taggaagtgg
    16381 accgagagat gggcttatga ttgctcttca gaaaaaaact aataaatctg tacgtcttgt
    16441 tagaacaatt cttgaaatac tagcattagt tgttggatgg ttattaggag gttctgtagg
    16501 tattggtacg cttgtaagtg ctttaggttt aggatatgta ttacaaatag tgtttagaat
    16561 atttaaattt gacacaaaat tgctgaaaca tagatttatt atagatgata taagagaatg
    16621 gaaggaaaag aaaagcaatg aacataaatg taaatcaagt attgtaataa aaaatgagca
    16681 gaattaatta tgctaaaata tatttgtagt ttatctaatt tatagtaaag tcaaggagat
    16741 tttgaaatgg aattatggga tttatataat gctgatggaa ttaaaacagg aaatgttata
    16801 aaaagaggta attctattga agaaggttat taccatttgg cagttgaagt gtggatttta
    16861 aatagtaact ctcaaatttt aattcagaaa aggtctaaaa gtaaaaaaac attgccaaat
    16921 atgtggggaa tgacaactgg atgtattgtt tctggggaag acagtttaga aggagcaatt
    16981 cgcgaagcaa aggaagaaat agggatagat ataactaaag atgagatgaa agtttttaga
    17041 agtatgattc atgaagatac tctttgggat gtatacttag ttaaaaaaga atatgatata
    17101 tctaaagcta ttttacagga ggaagaagta agtgatataa agtgggtaag cacagatgaa
    17161 ataagacaat tactaaaaga gggtttgttt tttgaatatc cagagatata cgaattgcta
    17221 tatgagatag ataataataa attaaatata tgatgtagag cagatttcag tataagtaag
    17281 attatttaaa atgtatcttc tctaaatttt aatattgttt tatgaaaatt aataagttat
    17341 ttttagtatt tttctacttg ttttttgaga ttaaaataaa aagggcagtc attataaagt
    17401 cataaaaatt tggggaggat ttaaactatg gaagataaca aaggattggc acgtgacagt
    17461 tcaaaatata aaattgtttc tatatctgtc gtagtaatta ttctaattac attttggtat
    17521 atgttaaata tggtgctttt aacatttatt atgactttta ttttctataa cttgcttgta
    17581 gccacaagaa aacgaattaa gaagttttct tctttaaata ttccagattc attgataatt
    17641 atagtgttat atgcactatt tgctatattg ttagtattga ttagctatgc agttgtacca
    17701 ataattatag ttcaacttac agagttgagt agggttttta gtgattttga tgtaaatcaa
    17761 tttgctcaat ctttaggacc gaaattgtat cctattgtct caaagctgga ttttaataaa
    17821 tatatttcac aagcagggct acttatagca tcaacagcaa caaaagttgg aagttttgga
    17881 gtaaatatat tattggcatt tttactgagt ttactccttt tacttgaaaa aaatgaaatt
    17941 aaaaattttg gagataaact ttctgatagt aagatttctt ttatttataa ttcgcttgta
    18001 ttttttggaa agagctttgt taaaaatttt ggtgaagtaa tgaaagtaca agttatgatt
    18061 gcctttataa attctgttgt ttctatgatt ttcttaggtt tcatgggatt ccctcaaata
    18121 tgggctttag gatttatgat ttttgtgttg ggtcttattc cagtagcagg agttatagtg
    18181 tctttgattc cattaactgt aatagcattt aatacaggag gaataacaaa ggtttttgga
    18241 gttttactta tgatttgtat agtgcatgca gtagaaacat acatattaaa ccctaagttg
    18301 atgtcgaata gaactaaact tccagtttgt tttgttttta ttattttact tgtaggagag
    18361 cattatttag gtgtatgggg attactaatt ggagttccaa tatttatgtt ccttatggat
    18421 attctgggtg ttaaatttac ttctaggtaa tatattaaaa taataattta tttttatata
    18481 taaattatga attgttttaa aaaagaacct ataaatagac atcattaata aagacatcta
    18541 tttgataggt tcaattttgc tttgtataaa tactataaaa ctaaataaaa agaaatttat
    18601 ttcatttcaa aagtttcaca acttgcattt ctttcattta tatgaacttt ttcagctttg
    18661 caaagttcat ttttattgta tttacatttt acagcttcac aatgaatgtt atctgtatca
    18721 acttggttag tttcattaga acgactagtt ataccagatg tatatttgtc ttcaaaagaa
    18781 gcacaataag tattttctgt agtagttgct tgcattccat ctacttttat actaccagca
    18841 taacaatatc cactagtatt ataagcacaa ttagtagcag cacaatttaa attattattt
    18901 ttcataaata acctcctaag ttttatttaa acttattatg tgaagttatc taaattttat
    18961 acacttattt acaattacat ttatcacatt taacaactac atctttggaa gtttcccttc
    19021 ctaaattttt attaacatga tacacatcaa cattttcagt tgatccacat atagaacatt
    19081 taaaattgtt ttctagtagg gttctttctt taaataactt ccaatacata gaattgatgt
    19141 aatcattata atttaccttg aggcatgtct caagaaagtt tatgtataga ttgtctaaat
    19201 ctcctgtatt taattctgta tattctggtt caaaatattc acaacatcct ctaaaatcgg
    19261 gctttgtatc tgaaataaca catctaatat catatctata gtctaggcta ggccccttaa
    19321 atgaaagatg tgtgcaaaaa gaacaagata tttctggtag atttttttca agttcatgta
    19381 atttattatt cataagtatt cctccaaaaa atttatttta agtatataaa tgaatagatt
    19441 attttaaaac ttttatttat ttatattaga gatttaggat aaatattcca ataaggagta
    19501 aatacttaag tatttattac tgtattaaat aaaaaagagg caaatctaac ttgagattgc
    19561 ctactttttt atcatttttt aataaaattt attctaagta ttattttatt tagatttagt
    19621 cagccaactt agtatctgct ttgcttttta actttctacc agagcgtaca gttaaaatag
    19681 catataatac agtaaatatg gcagctaaaa catatgatat atttatgttt aagttaaatc
    19741 caatttgagc attaaatata taactgaata taacaaagga ataaaacata ccaggaatta
    19801 agcttataat ataattcttt tcttttatta taaggtaaac tgtaatcatt gcaaatgcaa
    19861 atatggcaat agtttgatta ctccaagaga agtatctcca caatatatta aatccagaag
    19921 cactaagctt tgcaaatata aggatggcta tgacaggaat aaatatacag attgacaata
    19981 taacacgatg tttcttttcc ttttggtcat aatgaaagta atctgcaagc attaatctta
    20041 aagatcttaa agctgtatct ccagaagtta ttggtaaaac aattacacct attatagcta
    20101 tgataccacc aatagaacca agtaaatctc ttgcaaccaa acctattaca tcaggagaac
    20161 ctactaattc tttaggtatt cctttattgt aaatacccat agcagctgca gcccaaatca
    20221 ttgcaattaa accttctaaa atcatcatat tataaaaagt agtttttcct tctttttcat
    20281 ttgaaactga tcttgctata agagtagctt gagttgagtg gaatccagaa acaataccac
    20341 aagcaactgt aacaaagaat gtaggaataa gaggaatacc atcaggatga atacctttcc
    20401 aatttgcaag acttaaatta gctaaatcat aaccttgtgt aaagattcca attccaacac
    20461 cagcagcaga taaaagtaga atagctccaa atattggata tacctttcct atgattttat
    20521 caattggaaa tagtgttgca cacaagtaat atagaaagat aagtccataa actatccaga
    20581 caactggatt atttatagtc gatttcatat ttaaaatttg agtaacaact aaatccccag
    20641 gtgtataaat aaaaactgca ccaactaaaa gcattaaaag acaaaggaat atattataga
    20701 cttgaaatac tttattacct aaaaatctac tgataagaga aggcatttgt gctccttttt
    20761 ctcttatact aatcattcca ctcatatagt catgcaaagc tcctccaaat acacagccga
    20821 taggtattag tatgaatgct attggaccaa acaatatacc ttggataggt cctagaattg
    20881 gtcctgtacc agctatatta agcaactcaa ttagactatt tttccatttt ttcattggga
    20941 catagtctac tccatcactt tgagcaagtg caggtgtttt tctgtcatct gggccaaata
    21001 ctttttcaca ataagcacca tataaagcac ctcctattag taatatagcc aagccgatta
    21061 agaatgttgt cataatatca ccccatttat aaaatttttt ggtctttgta tacatattat
    21121 ctaaatgtgt agatttatat tgaatttaat tctggacaac ctacaaattc tataaagtat
    21181 tacaactaat ataatttcag aaataaatac atatacataa ccatgtactt agtatacagg
    21241 tatttggtaa tattttcaat gttatagcaa taaagaatat aaacaaaatt ctgataatat
    21301 tttacaaaaa aattaaaaaa tataaaaatt agtttaaata gatggagaaa aaaggaaaat
    21361 caattgagaa tataaatgtc tatatcttaa caatattaag aggtttaaaa ttcttgaaga
    21421 aagaatagtc aagtgatata atgggtttac aggtgtatat acactagtac atatagaaag
    21481 cggtgcaatt atggataaag atttaacata tcaaatcaaa gagctaaaga aagaaaaaaa
    21541 tgcaataata cttgcccatt tttatcaacc accagaaata caagaattag cagatgcagt
    21601 tggtgactca tattatttaa gtgagattgc tagagattgt aaagaagaag tggttgtatt
    21661 ttgtggagta aggtttatgg gagaaagtgc taagatatta tcacctgaaa aaactgtatt
    21721 gatgccagta agtaacgctg ggtgtgctat ggcagatatg gtagatgaag aaggcgtgat
    21781 aaaattaaag caacagtatc caaatgcttt ggttgtatgt tatataaact ctacagctaa
    21841 agttaaggca cattgtgatg tttctgttac atcttctagt gcaattaaaa tactagaaaa
    21901 catagataat aaagaaatta tattccttcc agataaaaat ttaggaggat atattgcaga
    21961 acaatttcca gataaaaact ttatattttg ggacggatat tgtaaatacc ataacaatat
    22021 aagagctgaa gaaataattg agttaaaaga taagtataaa aatgcagaag tattagtaca
    22081 tccagaatgt aaaaaagaaa taagagattt aggagattat gtaggtagta catcaggaat
    22141 aataaaatat gctactaata gtaaaaacaa agactttata atagcaactg aagaaggtat
    22201 attacatgaa ttaaagaaaa ataatcctaa taaaaacttt tatattcctg gtggaaaaat
    22261 actatgtaca gatatgaaaa agacaacatt agaaaattta tatagtacac ttaaaaatat
    22321 ggaaaatgaa gttattgtag aagatgaaat catggaaaag gctttaaatt cactgcttaa
    22381 catgcacaaa ttagcagaag gatagaggga tagacttatg aatttagaac aagatgtttt
    22441 aatagttgga agtggagttt caggattata ctgtgcatta aatttagata aaagtttaaa
    22501 tgtgctagta gtatcgaaat caacaattga aaacaacaat acatatcttg cacaaggtgg
    22561 aatttcaact gctagaaata ttgatgatat agaatccttt gtagaagata caatgaaggc
    22621 tgggcagtat aaaaatagag ttgaagcagt tcaagtactt gcagatgaat ctatagaaaa
    22681 tgtaggtcag atagtagaat atggtatgcc tttagacaaa gaaaatggag agatagatta
    22741 cacaagagaa ggagcacata gtgtaaatcg aatagttcat agtaaggata atactggaga
    22801 agttgttttt aaaactttat taaaagaagc taaaactaga gaaaatataa ctcttataga
    22861 agatgcatat cttttagata tattaaaaga tggcaataaa tgtataggag ctagaatttt
    22921 taaatctaaa aaagagattc atgttttttc aaaaatagta gttttagcta caggtggaat
    22981 tggtgggctt tttaaaaatt ctactaatca aagacatctt acaggtgatg gaattgcaat
    23041 agctttaaga aataatataa aaatagaaaa tttagaatat attcaaatac atcctacagc
    23101 cttttatgaa gaaaataatg aaggtaggag aatgcttata tctgaatcat taagaggaga
    23161 gggagctaaa cttttaaata aaaataaaga aagatttgtg gatgaacttc ttcctagaga
    23221 tgtagtttca aaagctattt ttgagcaaat ggaaaaagat aaattacctt atgtgtattt
    23281 agatgcaaca catttagata gtgaatattt aattaataga ttttctttta tttataatga
    23341 atgtttagct agaggaacag acataacgaa agaatgtata aaggtatctc ctgcacaaca
    23401 ttattttatg ggcgggatac atgtagattt ggattcaaaa acatctatgg aaaatttata
    23461 tgcagttggt gaaattagtt gtacaggtgt tcatggagcc aatagattgg caagtaattc
    23521 attacttgaa gggcttgtat tttcaaaaag agcagctaaa aatataaact cagttataga
    23581 taatgtaaaa gttaagttta tagatgtacc agatatggat atagatatag aacaggtaaa
    23641 aaaagaaaat aaaatattag tcataaaaga aattgaaaga acaagtgagg attttggcga
    23701 tgaattattt gattattgat agaatgatac aggatgcttt gatagaagat gttccaagtg
    23761 aagatataac aactaattct attgtggatg aaaattctaa atctactgta gatttaattt
    23821 gcaaacaaga tggtataata gctggcttag gtgtatttaa gagagttttt gagatacttg
    23881 gtgatgtaga tgtaaaatta tataaaaatg atggtgatag agtaaagaat cgtgaaaaga
    23941 tagctgtatt aacaggtagt actagaaact tacttgtagg agagcgtgta gcattgaatt
    24001 atttacagag aatgagtggt atagctacta ttacaagtag gtatgttgaa aagcttgaag
    24061 gtacaaatac aaaattatta gatagtagaa aaacgatacc taatcttaga atattagata
    24121 agtattctgt caaagtaggt ggaggatgca atcatagatt taatttatct gatggaatat
    24181 tgcttaaaga caaccatatt ggggctgctg gtagtgttaa gaaggcagtt gaattagcta
    24241 gaaaaaatac ttcttttgtt agaaagatag aagtggaagt ggaaacttta gacatggtaa
    24301 aagaagcaat agaagccaat gcagatataa taatgttgga taatatgagt ttggaaatgg
    24361 caaaacaagc agtagatatt ataaatggaa gagccattgt agaattttcc ggaaatgtaa
    24421 atttagatac tatagaagat ataggaaaaa ttggtgtgga tgttgtttct gtaggagcgc
    24481 ttacacattc tgttaaagct ctcgatataa gtatgaagaa tttgagaaat atataaattt
    24541 tatattgaaa taaacttaat taaaatagac tccttaaatt tgttttataa atttaaggag
    24601 tctatttttt attcattaaa attaataaaa atagaaaaaa atcaatcaat aatttaataa
    24661 aaatagataa atactatata cacttttaat aatatagtta atatctattt tacagataaa
    24721 taagaataaa cttataatat aattgtatct gtaaaatttt gtaaaatata aaaagtatag
    24781 ggggaataaa aatgaaagta gcttatattt ttagtagtac taatacacat aaaattctag
    24841 acaaaatgat aataccacaa cttgaacaag gaactcatgg agtagacgtt ctagggatgt
    24901 ttttctttat ggataatacc ttatttttat ctaaaggtaa tcctgtaggc gagagactaa
    24961 gtaaattaca tgaaaaaact gatatgataa taatggcttg tgaccaatgt gctatagaaa
    25021 gaggtataga gaataatttg gttgatggag ctacaattgg atgtttccca aacctatatg
    25081 cttgtttagg cagtgcaggt gtggaccaag ttataacgtt ataaattagt ataggataca
    25141 atccatagaa aaatttattt tctgtggatt attttaagta aaagataaat tgtttaaagt
    25201 aggggatgaa caaatgtcta aaattttagt tgaatttata aacacttgac catcttgtga
    25261 tgaacatgga gtgtttataa aaaaaatgtc agaaaagtat gctgataaat tggaaataaa
    25321 attatatcaa gcagggaaag atttttcgta tataaaaaaa tatgggatta taacaaaagg
    25381 aactttaata ataaatcaga aaaagaaata tgatagatta aataaagata caattgaaag
    25441 ggcaatagta gaagctataa acaataatta aaagtttaaa aattaggagt atcaaaaatg
    25501 aatatattag aaattgtttt aaatggagtt aaagatacta tagtagcttc tatagttaca
    25561 ctgaatggag catcaggatg gcttatgata agttttatct tggcaggtgt acttcacaat
    25621 gttttaactc caagaaggtt tcaaaaacaa cttggaaata agaaattttc ttctttaatt
    25681 aaaagtacta tctcaggaat gtttttacca atatgtagtt gtggagtaat accacttgga
    25741 ataagtatgt attattcagg agcatattta ggaccagtac ttgcttttat gacatcaact
    25801 ccaataataa atccaatagc tgtagttctt tgtctaggtc ttttaggtcc taaagttaca
    25861 atcatttatc taatagctgg ttttttagta ccatttttag taggattttt aggaaattgt
    25921 tttggaaaag aagaattatc acttcataat gattcagagg aagaagtaat agaattagaa
    25981 gaagaaaaaa gaagttttat ggaaaatatg attgatggtc ttaaatggtc ttttggtgaa
    26041 ttagccctta ctattagtaa atatgtagta atgggtatgg tttttgcagg atttataaca
    26101 actatttttc caaatagtat aattcaaaaa tatttaggaa atccaggttt gctatctctt
    26161 ggaagtatag caatacttgc atgtgttatg tatgtatgtg ctgtaggaca tataccgttt
    26221 atagcagccc ttgttgcaag tggagcatct cctggtatag cgataacatt tctaatagct
    26281 ggagcagcta caaatctacc agaacttata agtatgttta aacttattgg aaaaagaact
    26341 gttattatat attctgtaac tttgacactg tcttcaataa taattggata tataacaaat
    26401 ttacttttag tgaataataa ctcagtaaat ttagatgcaa caaattcttc aatacagttg
    26461 gcaaataaac taatgttaaa tatacctgat agttttgagt atgtatgtac tattttaatt
    26521 attttatttg catttaaatc aataatacca aagatgaaag aggtcatagg aaatcatgct
    26581 taaaaagata gttataatat cctgcatagt agttgtgtta atcattttat caaaaatagt
    26641 tgatgataac atcaaagaag atgcttctat tccaaatgtg aataaagaaa cattagaata
    26701 ttttagaaaa aattataaag aagacataat aacttgtgct gaagaagact taaataatga
    26761 tgggaaaaaa gatttagtag ttatatataa aaaaagcaat aattcaaatg aaatggtagt
    26821 cgtagtttct gataaaaata gccactatat aacaaagcca ataccagcac ctatagagaa
    26881 tcaaactata acctttaaaa atattgatga taaagcacca atagaagtaa ttgtatcagg
    26941 gtctaaaaat ggtaatgtag gatatgctat ttacagagta gagggtaaaa aatttgttga
    27001 tttatttggc gaagatatgg acaaatgttg ctaaaaataa aaataataca taaaggtggg
    27061 aaatttatat gaaattatct aagaagattc aagcattaat cttatttggt gtaatgggta
    27121 catctatatt aacaggatgt agtagtaaac caaaagaaaa agaagaagca aaaactggaa
    27181 aagatgatta tacaataaca gtaggttatt ataattgtga ccatatgact gcgggaccag
    27241 tagcagaatc ggcaggaata tataaagatt taggtcttaa tgtaaaaact gttggaaatg
    27301 gtaaagttcc tgaagctatg gcagcaggaa aaatggatgc aggttacata ggaactaagg
    27361 ggttagttgg agcaatacct aagggttcac caataacaat agcagctaac aaccatactg
    27421 gtggttctga atatttaata gtttcaaaag atataaaaga acctaaagat ttaataggta
    27481 aaaaaattgc aacagatatg agtgatttct tatggacaag tgattatggt ccagaaacag
    27541 gtctaccaac tgacccatca aaatatgaag ttgtaaatat ggattcagac aaagataaat
    27601 atttagctct taaaactggg aaaattcaag cttttacatc ttgtgaccct tggggttctg
    27661 tagctgaaaa tgacggtgca ggaaaaataa tagcatctac tcaatataaa gaaaaagcta
    27721 atggcaaaga atataactgt tgttcattct cattaaacaa aaactttata aaagaacatc
    27781 cagatttagc aaaaaaattg gttctagcac atacaaaagc aatagaatat atatatacaa
    27841 atccagctga agcagctaaa atatttgcaa aatattataa tgtagaagaa gaagttgcac
    27901 ttagaactat ctataagaag actgttggag aaggtagaac tcttacttgg aaagttacag
    27961 gtgaagaata taaaaataat ttacaaatgt ataaagattt aaaggcttta gatgatatac
    28021 ctaaatatga agatacgatt gatacaagct tattggactc ttgtggagct gatgattttg
    28081 acaaatttat aaaagaaaaa gttaacccag agtttcctga aggtatgagt tatgaagact
    28141 ggaaagcaaa ggtattataa ataaatggag aatatgaaaa atataataat actttttatc
    28201 attattttgg gaagtatatt tataatattt tttaattttg aagataaaga agaaataaaa
    28261 ggaaaattaa gaataggggt atctgatgat acctctggtt ttgtaataaa ttatatggta
    28321 aatagagact actttgaaaa tataaaagta agtgatataa tggatatttt tacaattaat
    28381 gattgctgag caagtacaat gcagtgggct ctgagttcag aggaaataga tatagcaatc
    28441 atatgtaaag atgctgcaaa acaatatgta aatgtaaata gtggatttga aattgttggt
    28501 actgtagttc aaaattctga tatatttcta ttaagtgata ataatcctga aaagatagga
    28561 gtcattcaaa atagagatta ccagtcagaa ttggttaaaa aatactacaa gaatgtggaa
    28621 gtagctccct tattagggac tgcactagca tatggattag aaagtaattt agtagatggt
    28681 gttgtaatag attgcataaa gtcaattggg ttagagggca aaagaaaatc tacaactaaa
    28741 ttaggagatt atgataccta tgtattagtt gtaagtaaag agtttaaaaa aagtaaagca
    28801 tatagtgatt ttataacact ttacaataaa agtgttgatg ctttaaagaa taaagctaca
    28861 tttaagaaag cattaaaaga gtacaggaat ataagaaata tagatatgga ggaaataagc
    28921 aattggaaat taaaatttct aaagataaaa gcgatagatt aactaagaaa aaaactgatg
    28981 gtagtatgga tattttatat aaaataatac tattagttat tatattttta gtctggcatt
    29041 ttgcagcaaa agatataggg agttctttgt tacttccaat gccagtagat gtaataaaag
    29101 gtttcttttt ctgtgtgaca gatgcagaga cagtcactaa tctttttata acattgcaga
    29161 gagtacttaa aggttttatg tatgcattat tgtttgggct tccaatagga tttattatgg
    29221 gattttctaa aacttttgaa agggttttat ctccagtagt agattctgta aggcaagttc
    29281 caataatggc atgggttcct cttactatag tatggtttgg tataggagat ggtccaacaa
    29341 tatttttaat agctttttca ggggttttcc ctataatttt aaatactatt caaggagtaa
    29401 gagcaatatc aaaggattat tataatgcag ctagaagtat gggagcatcg ccaattgtga
    29461 tatttacaaa tgtaattgtt cccgcatctc ttccagatat actaactggt tcaaggattg
    29521 ctataagtac aggatggatg tctgttatct gagccgagtt tatagctacg agtgccggtc
    29581 tcggttactc aatggtacaa gctcaaacat taatgcatac agatgtatta attgggctta
    29641 tgatatttgc agctttaata ggatttataa tagatagggt attaaagttt ataaataaaa
    29701 tcctttgtag atggaggttt gcagattaat gaagttaagt gtaagagata taaataagac
    29761 atttgtaaat aatagagtac atacaaaggt tttagaagat ataagtatgg atatagatga
    29821 tggacaattt gtctgtcttt taggaccatc aggttgtgga aaaacaactt tacttactat
    29881 aataggtggg tttcaaaaat cagaacgtgg agatgttttt ataaatgata aaagagttaa
    29941 aaaaccgggc atagatagag cttttatatt tcaaaattat gctttatttc cttggaaaac
    30001 tataagaggt aatgttctat ttcctatgaa acagcagaaa ataccaaaag aaaaaagaga
    30061 agaaatgcta gaagaacttt tggttatgtc agacttgaaa ggaaaagaaa aactgtttcc
    30121 gcatcaatta tctggaggaa tgaaacaaag agtggccatg ataagagctt tagcatgtaa
    30181 tccagaggta ttactaatgg atgaaccatt aggagctgta gattttcaaa tgagacaaaa
    30241 tttacaggaa gagctagaac gaatatggat aaagaagaaa ataactgcat taatggtaac
    30301 tcatgatgtt gatgaagctg tatatatgag tgatagagtt atagtaatgt cgagagataa
    30361 aggaagaatt attgatgata taaatataga tattccaaga cctagaatta gaggaagcca
    30421 aaaatatgaa gagtacaaaa acaaattaac tgatacttta tcaaagtgtt atgaagttta
    30481 aagaggagta gacatgagtc aaatagaaaa atacaatagt ttggataata cacaacagaa
    30541 aataagaatc tctattatgg atatgataat agataaaggt tctagtgtta cacttcaaga
    30601 agtgactgaa tatataagta aaaagttgaa tatagaaaaa gaatatatag aaaggacact
    30661 acaatatttt atttataaaa atataatggt tgttgatggg aatagtataa attttatata
    30721 tcctgtatca gcattgccaa caaatcataa agtaactttg agagataata gaagtttcag
    30781 tgcaatgtgt gctatagatg ctataggaac ctcttgcaca ttcaaccaag atataaaaat
    30841 aaactctatt tgtagtgcta caggtaagga aatagaagta attataaaaa atgaaaagat
    30901 tgagtatgtg aataatccaa acttaagagt gcttcatata aatcttgata agcatctaaa
    30961 ttgggctgct agttgctgaa atataatgaa tttcttctgg acgaagagtg attttgatgc
    31021 ttggacaaac gaagcgggat tatctaatga tgaagatata tattgtttag atattaatga
    31081 ggcaatagta gaatcatata aaatatttaa actcaaacaa aaggtactat catagatata
    31141 catatatgaa aaactaaaaa tgacctttag ataaaaatga taggtaatat ccatactata
    31201 taaattagta tagagtaggg atgtgaaaag tatttaaatc taaaggtata tttttagttt
    31261 tttttagatg attagatagc cttattaagt atatatttat ttataacctt tgcaactcca
    31321 ttttcattat tagtatcagt aacataatct gcaatttcct ttatactatt acgtgcattc
    31381 cccatagcca caccaagacc tgcatacttt atcatatgtt ggtcattttc ttcatcgcca
    31441 acagcaatag cattttctat aggtatattt agattcgtac ataatgtttt aagagcagtt
    31501 cctttattag tagttttacc taaaaattct agataaaaag gagcagacct tactatagta
    31561 tatttattga ataaattttt aggtagttgc tgtatgattt cttccaatct ttctggttca
    31621 tcaactatca taattttaca gattttaata gattcatcaa ttttatcttt ttgtatatat
    31681 ttgacttcta tattatttaa tttcgcttca tgaagtgtat atttgccagg cgtttcattt
    31741 ggtgtaatta aatttgtcat tgtatttatg tgtattttag tcttatattt tttacaaacg
    31801 ttattatata taaaatcaaa atcatctaaa ctcatttcta catcatgtat gattttctca
    31861 cttttaactt cttgaataat tgctccatta aagcatataa cataatcacc ttcatctgtt
    31921 aaatttagtt gatttagaag ttcttttaca ccaggaagag gtctgcctgt tgttataact
    31981 acttttgccc cagccctttt tgcctcctga atggactcaa agacttcagg agtaatcctt
    32041 ttttgtgtat ttaatattgt tccatcaatg tctagtgcga ttaatttgta catatcaacc
    32101 tccaataaat tatatactca aatttcctgt gaaaacgttg acacagctag tgttgaacaa
    32161 agtttcagtg ggaaatatgg tttgttttgt atactattat atcaagagat aagtaattta
    32221 gaaagtttaa taatattaat tttttgataa aaatattact tatgtgagat gagaatgtaa
    32281 aaactttgta atcaataatt ccaaaattct taattacaaa taatggtatc gtttgcattg
    32341 ttaatataaa taaatgtata ttatatagtt agaagtttga ataaatagac tgatggtaat
    32401 ttgttatatt agttagtttt gtgttataaa atattgtaat tccattaatc atatgttatt
    32461 attcaacatg attataatat aaagaatatt tgatatatat aataatttat aaaagagtat
    32521 tacatagtac atgtaaatct atatttataa atacaataaa gtaaagttgt aaaggagtgc
    32581 tttaaatgaa gttttcagag tttaagtatg aaagacccaa ttataatagt atgaaaaaag
    32641 agtttttgag ttgtgtagaa gatataaata attctcgtaa ttataaagag caacaaaaaa
    32701 atatacataa gattaattta ttaagaaata aaatagaaac gttgtcaaat atagcttcga
    32761 taagatatag tacagacaca tttaataaat tctacaaaga agaaaaaaat tattgggatg
    32821 aatatatgcc tttgtatgaa gaattaaatt catattttta taatgccatt gtaaattcaa
    32881 aatttaaata tgatttgata aaagagtttg gagagcaatt tttcacaata gtagagtatt
    32941 ctttaaaaag tttttccaaa gaaataataa gtgaattgca ggaagaaaat aaattgtgtt
    33001 cagagtatac tagactttta gcttcagctg agataatgtt tgatgggaaa ataagaaatt
    33061 tatctggtat ggggaaattc atgtattcta agaatagaaa aacaagagaa ttagcaaaca
    33121 aagcatatta taatttcttt gaagaaaatg aaactaaatt tgatgacata tttgataaat
    33181 tggttaaact tagagataag atgtctaaaa aattaggttt tgaagatttt gtagagcttg
    33241 ggtatgttag aatgatgaga agtgactaca gagaatatat gataaaaaat gttagaaaac
    33301 aagtactaaa atatgttgtt ccaatggcaa atgagcttta tgaaaaacaa gctaaaagaa
    33361 ttggtctaga atatttaagt tacatagatg aaggcgtgga atttttaaca ggaaatgcaa
    33421 gtttaaaggg agattcaaga tacataatta aaaatggtaa aaggatgtat tctgaactgt
    33481 caaaagaaac aaatgaattt tttgatttta tgttagaaaa tgaacttatg gatttagaaa
    33541 cgaagaaagg aaaaggagct ggagggtatt gtacttatat accagattat aagtcaccat
    33601 tcattttttc taattttaat caaactgctg atgatataga tgtattaaca catgaggcag
    33661 gacatgcatt tcagttgtat atgtctagat ggattgatat gccagaaatt aattttccaa
    33721 cgcttgatag ttgtgaaatc cattcaatga gtatggaatt tataacatgg ccgtggatgg
    33781 atttattttt taaagaagat acagataagt acaaattcac tcacttatca tcttcaatta
    33841 aatttatacc ttatggagta attgttgatg aatttcaaca ctatatttac aaaaatccta
    33901 atgtagataa gtcaaaacga aaagaaatct ggagattttt agagaaaaaa tacttacctc
    33961 atagaaaata tggtgataat tcttttttag agagaggttg ttggtggttt aaacaaggac
    34021 atatatttaa aaatccgttt tattatatag attatgtatt agctcaaatt tgtgcgttac
    34081 aattttggaa aaaaatgatt caagatagag atgcaggatg gaaagattat ataaatatct
    34141 gtaaagttgg aggaacaaaa tcatttttag atattgtgag tatgggaaat ttgtattctc
    34201 catttgatga tggctgtatt gagtctatta taggtgatgt taaatcttgg tttgatgaaa
    34261 taaatgacag caaattataa aaaattatga gaattttatt gtataaaagt gaaaaattaa
    34321 aaaatatata aaaagtgatt atttgttgtg aaaatagtct tgtttttaac taaattgata
    34381 aaataaacta aaaaagattt gtacttaaaa aaaaaagaaa atacaagaaa tatgcaatat
    34441 caacatttgg aaaaaaaagt aaaaatgtat acaaaataca tataaaaaaa ctattgcaaa
    34501 ttttatagaa tgtttatata cttaagtcaa cagagataga aaaaagctat ttatagaaaa
    34561 caaaggataa attgcttaat tttaaatttt ctgaaaaaaa taataatccg gatgaagagt
    34621 atgggagact gctttataaa aagcgaccga agggacaagt ttaatcttac ttacccaaaa
    34681 gattagatga aattctcagg taaaggtgac tgtacttgga cggggctctg aaaatgattt
    34741 taacagggaa gacaaattgg gagatttgtt tttcctgttt tttatttatc aagtaataaa
    34801 taaaagtttg aaagagagta aaaaaatgat aataattacg aataatccaa aagtaaaaga
    34861 agaagttcaa ggcagagaag ttttgtttaa agacacaact tatattggaa tcttagaagc
    34921 aagtagagat ttgatacatg aaggttatga acttttatct catccactct atgggagtgt
    34981 aaagccaaat gaaacacctt acaggactgt tatactaaag aaaggaaatc gtttggatat
    35041 aaactcttta accttaattg aagaagcaat catcactgca agtaaatttc agaataataa
    35101 aaagactcca aaatggacag aaagtgttca agatgatttt agagtaattg attatgatat
    35161 attttataat acaatacaaa gaatgcagta tgaataaaaa aaaattgtta aaaagttatt
    35221 aaaacagcct aaatattaaa tctaatttaa tattaaataa aatgagaaat ttaattgggg
    35281 aggataagtc aaaatggaaa atgtgtatga cttagtaata attggttcag gaccagcagg
    35341 gcttgcagca ggtctttatg gagcaagagc aaagttaaaa actctaatcc tagaaaaaga
    35401 caagactggt ggacaaattg taataacaca tgaaattgca aattatccag ggtcagttcc
    35461 aaatgcaaca ggaccaagtt taatagctag aatggttgaa cagtgtaaag agtttggagc
    35521 agaaatgcta agagacaaca ttgttgatac tgagctagat ggagatataa aagttttaaa
    35581 aggggaaaag gcagaatata gagcaaaagc agtaataata ggaacaggag caacaccaag
    35641 aaagattggt tgtcctggag aaaaagaact tactggtaaa ggggtttcat attgtgcaac
    35701 ttgtgatgca gatttctttg aagattttga agtatttgtt gtaggtggag gagacagtgc
    35761 attagaagaa gcaatgtatt taactaaatt tgctagaaaa gtaacaattg tacatagaag
    35821 acaaggattt agatgtgcta agagtgttga agaaaaagca aaagctaatc caaagataga
    35881 gtttttatta gatacagtaa ttgaagaaat caaaggtgat ggaatattag aatcagttgt
    35941 atttaaaaat aaagttactg gagaaactca tgaatacttt gcagatgaag aagatggaac
    36001 aatgggagta tttgtgttcg ttggattaga tgctcaaact gatttattca aaggtaaagt
    36061 tgatatggat gaaaaaggtt acataataac tgatgaagat atgagaacta acataccagg
    36121 cgtatttgca gcaggagatt gtagatctaa gactctaaga caggttgtaa ctgcaactaa
    36181 tgatggagca attgcatcta tagtagctga gaaatacatt gatgaaaaat ttgggaacta
    36241 gaatctgtaa attaagaaat agtgtctgta aatttaatga ataatattta aaattaaaat
    36301 taatatttaa aataaaaata aaaatttcaa gggggaataa gaaaatgtta gatttagata
    36361 aggctacatt tgaagaagaa gttttaaatg cagaaggttt tgtatttgtt gatttttgga
    36421 gtgaaggttg tgagccttgt aaagctttaa tgccagatgt tcataaatta gctgagactt
    36481 atggggataa aataaaattc tgtaagatgg atacaacaaa agctagaaga ttagctataa
    36541 aacaaaaagt attaggtctt ccaactatgg ctatatacaa agatggagaa aaagtagacg
    36601 aagttactaa ggatgatgct acagttccta atatagaaaa catgattaaa aaatatcttt
    36661 aatatgttga taaattatta acattaaaag aaaaaatcta tttttatctg aagataagaa
    36721 gaaaaaggtt tttatgtcca actttgttaa aaaaataatt ttaaataaaa taattttttt
    36781 acaataaata ttttttagta ataaaataaa gatttaaggc ataaaaacac aataatatat
    36841 ctttaaaaaa ataagataaa ttgtaaaatg atataatttt gagaaaaact caaatgcata
    36901 tacacaaatt aaataacagg aggtgcaagt atgcgtcttg aattagggaa aatctttata
    36961 aaagatattc aatttggtga tgtaacagaa gtaaaagatg gagtattatt catcaataag
    37021 caagagatgc tacaagaaat tggtggagat gagcatatta aatctataga tatagaatta
    37081 gctcgtccag gtgaaagcgt aagaataaca cctgtaaaag atgttattga gccaagagta
    37141 aaagttgaag gtaatggggg aatcttccct ggtatcatgt ctaaagttga cactgtagga
    37201 gaaggaaaaa ctcatgcttt aaaaggtgta gctgttgtaa ctactggaaa aatagtaggt
    37261 ttccaagaag gtataataga catgactgga gaaggagcta agtacactcc attttctaaa
    37321 ttaaataatg tagtagtaat agctgaacct attgatggtt taaaacaata cgctcatgaa
    37381 aaagctgtta gaatgatagg attcaaagca gcaatgtact taggagaagt agcaagaaat
    37441 cttactccag atgaagtttc agtatatgaa actaaacctc ttcttgaatc aataaaagaa
    37501 tatccagagc ttccaaaagt aggatatgtt tacatgcttc agactcaagg tttattacat
    37561 gatacttatg tatatggagt agatgcaaaa caaatagtac caactttatt atatccaaca
    37621 gaattaatgg acggagcaat tgtaagtggt aactgtgttt ctgcatgtga caaaaaccca
    37681 agttatgttc atataaacaa tggggttgtt gaagacttat atgcaagaca tggtaaagat
    37741 ataaactttg taggtgtaat tataactaat gaaaatgttt atctagcaga taaagaaaga
    37801 tcttcaaact ggacttctaa attatgtaaa tatttaggat tagatgcagt tatagtttca
    37861 caagaaggtt ttggaaatcc tgatactgac cttataatga actgtaagaa gatagaaatg
    37921 caaggtgtta aaacagttat agttacagat gaatatgctg gacgtgatgg aggttctcaa
    37981 tcacttgcag atgcagatgt aagagctgat gctgttgtaa caggtggaaa tgccaaccaa
    38041 gttgtagttc ttcctaagtt agataaagtt attggacatt tagaagtagt agatgtaata
    38101 gctggtggtt ctgatggaag tttaagagct gatggaacta ttgaagttga aatccaagct
    38161 ataacaggtg caactaatga aacaggattt ggtcatttaa ctgctaaagg atattaagaa
    38221 gtattttatt aaacgattga gtaatgttaa taaaacatat tatagataat tataataagt
    38281 gttatagata tataaaaata tattagaaat ataataagga ggattattat gagtttactt
    38341 agtaataaaa aggttcttat aataggtgac cgtgatggta taccaggacc tgcgatagaa
    38401 gaatgtgtaa aaacagtaga aggagcagag gttgttttct catctacaga atgctttgtc
    38461 tgaacagctg ctggggctat ggacttagaa aatcaaaaca gagttaaaga tgctgctgat
    38521 aaattcggag ctgaaaatgt tgtgatttta ctaggtgctg ctgaagccga agctgcaggt
    38581 cttgcagccg aaacagtaac tgctggagat ccaactttcg ctggaccact tgctggagtt
    38641 gccttaggat taagtgttta ccacgttgtt gaggaaccaa taaaatcatt atttgatgaa
    38701 agtgtatatg aggaccaaat aagtatgatg gaaatggttt tagaagttga agaaatagaa
    38761 gaagaaatgt ctggtataag agaagaattt tgtaaatttt aatgcctaaa agcaaaaggg
    38821 gtgaaactaa gagatgggaa aactaaaagc agtacattat attaatcagt tctttgctgg
    38881 tataggtgga gaagaaaaag ctgatactaa gccacatgtg gcagaaactt tacctccaat
    38941 aagtttacaa cttgataaat tattaggtga agatattgaa atagttggaa cagtagtttg
    39001 tggagatagc tatttcaatg aaaatataga tagtgcaagt gaagaagttt tatcaatggt
    39061 aaaaggtttt gaaccacaac ttttcatagc tggtcctgca tttaatgctg gtagatatgg
    39121 ggttgctgct ggaacaataa ctaaagttgt aaaagatgct ttgaatatac cagctttaac
    39181 aggtatgtat gttgaaaatc caggagcaga tatgttcaaa aaggatgttt atgtagtaga
    39241 aacttctgat tctgcagcag gtatgagaaa ggcacttcct aagatagcta aacttgcagt
    39301 aaaacttgct aatggagaag aaattggaac tcctaaagat gaaggataca tagctagagg
    39361 aataagagtt aactacttcc atgaagacag aggttctaag agagctgttg acatgttagt
    39421 taagaaaata aaaggtgaac catttgaaac tgaataccca atgccaaact ttgatagagt
    39481 tgacccaagt aaagctgtaa aagatttatc aaaatgtaaa atagctttag ttacttctgg
    39541 tggtatagtt ccaaaaggaa atccagatag aatagagtct tcttcagctt ctaaatatgg
    39601 aacttattct atagcaggag ttatggattt aacagaagag acttatgaaa ctgcacatgg
    39661 tggatatgac ccagtgtatg caaatttaga tgcagataga gtattacctg ttgatgttct
    39721 tagagattta gaaaaagaag gtgtaattgg aaaattacat gagactttct atacaactgt
    39781 aggtaatggt acatctgttg caaactctaa aaaatatgct tctgaaattg gagcagcatt
    39841 agtggctgat ggtgtagatg cagtaatatt aacttctaca tgaggtactt gtactcgttg
    39901 cggtgcaacg atggtaaaag aaatagaaaa aactggactt ccagtagttc atatgtgtac
    39961 agtagtacct atttcattaa cagtaggggc taatagaata gttccaacta tagcaatacc
    40021 tcatccactt ggaaatccag cgcttgaccc tacagaagaa aaagccctaa gaagaggcct
    40081 tgtagaaaaa gcattaaatg ctttaactac agaagtagat ggtcaaacag tatttgaaaa
    40141 ataaaaataa cacacacata tattatatag ataaaaatat aaacacacac taaaaataaa
    40201 aaataactat acacaaaaaa ataatataga tttcatgaat ggataaattg gagttattca
    40261 ttcatgaaat cttaaaaaat gccaaaatac ataaacaata atagaatcaa atatacaata
    40321 aaatacaatg attagagctt ttaataagtt taataagatt aaaaaataag tgttcataaa
    40381 atttatggag gtgcacaaaa tgacttatcc agttttaaaa ggggcaggct atgtacttat
    40441 tcatactcca gatatgatag tgcaaaatgg aagtacttgt acagttgaaa gagcaacaaa
    40501 tccagattca gaatttttaa aagaagtaag taatcatata agaagttatg aagatgtagt
    40561 taactacatg ccaaatcaag tttatatagg aaatagaaga ccagaagaat taagagattt
    40621 accaatgcca tggtgtgaac aaaagattga gggaactaga aatggtaagt ttggagaaat
    40681 aatgcctcaa gatgagttca tagctttaat gcaaataagt gatgcatttg atttagtaaa
    40741 attatcacaa gaatttattg atgaagtaaa gccaaaaatc gaaaataact accctgaaat
    40801 tgcaccattt gtaggtaaat taaagggtga tgatatagaa gaaggtaaag aattagtagc
    40861 aacacacata gctgaaggat tataccatga tggaaaattt gttggttatg taaaaagagc
    40921 acatgatgta gatgttaact taaatgccca tacaatgttt gaaaatctag tagtaaaagc
    40981 atctggagtt ttatctgcta ttcaaatgct aagacatagc aaaatagacc ctgctgaaat
    41041 agattatgtt attgagtgtt cagaagaagc ttgtggagat ataaaccaaa gaggtggagg
    41101 aaactttgct aaatcaatag ctgagatagc aggacttcaa aatgcaactg gttctgacac
    41161 aagaggattt tgtgcagcac caactcatgc attaattcaa gcagcagctt tagtaaaagc
    41221 tggcatacat aaaaatgtaa tggtagtagc aggtggagca agtgctaaac ttggaatgaa
    41281 tgctaaagac catgttaaaa aaggtcttcc tgtacttgaa gatgttgttg gaggatttgc
    41341 agtacttgta tctgaaaatg atggtgtaaa tccagttata agaactgatt taacaggtaa
    41401 gcatactgtt ggaactggtt cttcaccaca agcagttatg acagcactta taacttcagg
    41461 tcttgataga gctaatttaa aaataacaga tgttgatgtg tattcagttg aaatgcaaaa
    41521 cccagatata actaagccag caggagcagg agatgttcca gaagcaaact acaaaatgat
    41581 aggggcactt gctgttaaac gtggagactt agaaaagaaa gaattgaaag attttgtttc
    41641 taacaaagga ttaccaggat gggcaccaac tcaaggacat ataccatcag gagctcctta
    41701 tataggattt ttaatagatg atttaactac aggaaataga aatagagcta tgatagttgg
    41761 aaaaggtagt ttattcttag gaagaatgac taacttattt gatggagtat cttttatagc
    41821 tgaaagaaat acaggtgtta ctgaagagac ttcaggaata tctaaggatg aaattaagaa
    41881 gataatagct gaatctatga aaaaactagc attagatatg ttagaagaat aggggtgagg
    41941 atatgtcaaa aaaagtaatc gcagatgtat tcttagaagt agctaatgca atagaaagcg
    42001 gcgaatttgg caaaaaagta aaaattggtg ttactacact tggaagtgaa catggtgtag
    42061 aaaacatggt taatggtgca caattagcaa aatctaattt atttgatatt gtgcttattg
    42121 gaccaaaagt ggaaactgac cttgaagtag ttgaagttaa tgatgaaaaa gaaatgcatg
    42181 caaaaatgga agaattatta gattcaggat atattgatgc ttgtgttact atgcattata
    42241 attttccaat aggtgtatct acagtaggta gagtaataac tccagcaaaa ggaaaagaaa
    42301 tgatacttgc aacaacaaca ggaacaagtg ctactaatag aatagaggca atggtaagaa
    42361 atgccattta tggtattgct acagctaaat caatgggtaa caaatgccca aaagttggaa
    42421 tacttaatgt tgatggagca agacaagttg agaagtgctt aaaagaatta aaagataatg
    42481 gatatgacat ggagtttgcg gattcaatta gagcagatgg tggatgtgta atgagaggta
    42541 atgatttact tgtaggtgca cctgatgtta tggttactga tacattatct ggaaatatat
    42601 ttatgaaagt attttcttca tatactacag gtggagatta tgaagctcaa ggctttggat
    42661 acggacctgg agttggagag gactatgata gaaaggtact tatagtatca agagcatcag
    42721 gttctccggt agtagcaaat gctttaaaat acgcttatga tgttgtaaag ggagatataa
    42781 gtaatgttgc aagaaatgaa tttgcaaagg ttaaaaaagc aaaatttgat gacattatat
    42841 cctctcttac taaaaaagaa gttaaagctg aaaaagtaga agttaaaatg ccagataaag
    42901 aaattgttac tcgtcaaata gctggtgttg atataatgga tttagaagat gcagtatctg
    42961 agttatggaa aaacggaatc tatgctgaaa gtggtatggg ttgtacaggt ccaatagttt
    43021 tagtaaatga agctaaagga gacttagcag ttgaaacttt agttaaagct ggatatactg
    43081 caaaataagt acatttttta tatgtaaata agaacatata gttataattt tattgattat
    43141 aattatatgt tctttttatt ttatatcttg tcaatattta tatattaaca caatccattt
    43201 atttgattct ctagctaatt tattatattt attcagttaa aattaagctt tctaactaaa
    43261 taaaaactaa tgaagtatta aaatgaaatt gataaaatat gaaaaaattt taggaataaa
    43321 gtatctgtta gataaaaata agattaatta gtgatataat ataattaaga taaaatttat
    43381 tatttggagg caaaatcatg agcagagtaa aaaatgtagt agaattgttg gaaactaaag
    43441 gtgttgatgc actatatcta acaaagaaaa ctaatgtaaa ctatataagt ggttttcctg
    43501 atgaagaagc atatgcagtg atttgcaaag atggaaactt tttagttact gatagtagat
    43561 atatggagct tgcagaaaag gtttgcaaag attttgaaat tataaattgg cataattttg
    43621 atagaagtgt ggcaaaggca gttaaaagtg tatgtgataa agtgggtata aagaaacttg
    43681 ggtttgaaag aactaatata gtgtttgata aatatgaaga acttaaaaat ctgattgaga
    43741 aggataatgg agaattaata cctacagaaa atattgtaga gactttgaga tatgtaaaag
    43801 acaaagatga aatcaaaaat acaagaaaag cttgtgaaat agcggataag gcattagaag
    43861 aattgattcc acatataaaa gctggagtta gcgaaattga actggctaca aagttagagt
    43921 actttatgaa aatgaacgga gcacaaaata tagggtttga aactatactg atatcaggag
    43981 caaagacttc attgcttcat ggtaagccta gtgataagat tatagaaaaa ggtgattttg
    44041 tacttataga ctatggcgct atgtataatg gctatatatc tgatacaact agaactttta
    44101 tagttggagg agcttctgaa aagcaattag aaatatataa tttagttaag gaagctcaaa
    44161 atgtaggggt tgagaacatg aaagctggtg tacatgcgac aattccagat gctgagataa
    44221 gaaaagttgt caaaaaatat gaagactatt actatcaagg tataggacat ggagtcggta
    44281 gagatgttca tgaagaacct ttcattggta attatggtga taaaatcata gaagagggat
    44341 gtataataac aatggaacca ggtatttatt tccctggatg gggtggagtt agaatagaag
    44401 atactgtttt gattactaaa aatggtccag aaagacttac taaattccct aaagatttga
    44461 tgattttaga caaataattt aatttatata tattttttta cataaaatat aacataatct
    44521 cactattaag ctctatttac atattatagt aaagagggct taattttatt gtgagaggtg
    44581 atagtatata tgtataaaaa acataaattt ataaaaaata taaaaaaagc ctggtataaa
    44641 atcaaattaa ttgatagatg ccttataatt gtaatggcaa tattaatgtt tcaatctata
    44701 tataatttat ttgttaatga agtaaattca caagatacta caactattga tgtagtagta
    44761 agaaccactt cagcagctat atttgggtat tttttaagtg ctaattttat aaagagacct
    44821 ttaaggaagt atacaaatac tgatgtatct tcaaatcttt ttatagataa taatttatcc
    44881 ccaaaaggtc aagagtctaa tcaaaataat ataatgaatg tcaaaaatac cattggattt
    44941 acttcagaag ctgataatta tgaaaagaaa atacctatta ataataatga aggttttgaa
    45001 gaaggagaaa ctagtgaatt gcaaattatt atagctactg taatttgtat agtagcatta
    45061 acagtacttt ttgttgtaag aaattttaca actacaacat cagcttcttt aggtactatt
    45121 tcacagatga gagattttgt ctcaggatgc gtgggttttt tgctaggttg tccaagtaaa
    45181 cctgattaaa aaagtattat caataaaagg tattttaaaa agtatcagta taataatatt
    45241 tagatttaaa tgtatacaat tataattcta aacattctat attgtatttt tatactgata
    45301 ctctaaacta tactatttat taaaatattt taacattgta tttaaacaaa atattatatc
    45361 tgtataatat aaatttagtt tatatgaata gatgccatat actcaataaa aagtttcata
    45421 ctatgagata tgtattgatt tcttctccaa agaaccccaa tattcgcagt aattgcacgt
    45481 tctaatggta ttgaacagag attttctgta ttttgaaata tttctttata caatattgtt
    45541 gaagccaagt cattttctag taaataacgt atggtagaaa gttgatttga gtgtaaaatt
    45601 atatttggct tagctttttc aagtcttttt gtaataatct tatagtgata agaaccttca
    45661 gataagatta caaaaggtac attttttaac atataattcg atataatggg atgttttgcc
    45721 aattcatttt tgggatttgt aactaagtat aattctgttt tatagattgt ctttgaatct
    45781 atatcatcat aaatatcact gtcaattata ccaatacaaa aatcaagtgt agattcttca
    45841 atcattttag ctccaacaaa tgttggaact tcaaaaattt taagctctat atctggataa
    45901 attacattaa atctaggaag tatttttgaa agcaaaaacg tacctaaaac tgtaggaata
    45961 cctattttga gagaagcttt tctctttttt cctaaatcaa gtgcgtcaca ttgaaaatcc
    46021 tcaaattgtt ttataaaatg ttttgacttg tctaaaaaaa tttttccttc aggcgttaac
    46081 tctattttat tacctattct gtaaaaaagt tcaaagccaa gttctttttc taattcttta
    46141 attgctaatg ttatggatgg ttgagaaata tgaatacttt ccgcagcctt agtcatgttt
    46201 ttatatttac agacagtttg aaaatagtat aaatagttta tattcatttg gtattagttc
    46261 ctttcattta catattagtg acaagtatat aattaacaat agcataagtt ttgtatattg
    46321 ttgtaaaaaa atagaatagt tttaaactat catagcataa gtttttgata ttttcaatct
    46381 attaagaata gtgctattat taaattaaca aaagagaata gctggtatgg tttagagtaa
    46441 atcaatctat attacagtta tatcaacgaa tatcaaaaaa ttatctatta gaaaataaaa
    46501 attattttta caattaaatt gttaattaaa tcataaagaa aaaagtgata ttaacaagat
    46561 aaaatttttt taatcagaaa tgttaattta ataacaaaat agagtattgg ggagaaagga
    46621 gaaatatatt ttttaataat atttgttaat ttaataacga aaaatgaaag ggagtgattt
    46681 agtgaagttt gaattgatgg attttttaat gaatcctttt gtccttatgt ttgctgcagt
    46741 aattacagga attttatttg gaaaaattaa atttgggaag tttaattttg gggtatcagg
    46801 agcattattt acaggattat ttattggatg gcttgcatat agcttgggga atctaataat
    46861 agcaaaaggg gaaacagcag caggatataa ggcagcaact gtaatgatgg gtaatggaat
    46921 tatttcttct gacttctttg atttcttttt aataatattt gttgcagcag ttggtctatt
    46981 ggcagcaaaa gatatgaaag ctgtattaaa gaagtatgga gcaagatttg taattttagg
    47041 agttcttata acttttatag gtggctctat gacttatgca atgactttac tatcaagtga
    47101 taaaggaagt agtgcttatg aagtttctgg cgtttacaca ggagcattaa caagttcgcc
    47161 tggattagct gctgctttag aaacagctgg taaacatgca gaagatgtat caaaagaatt
    47221 tgaaaaagct tcaataaaag ataaaaaaga aattttaaaa gtagtcgacc cagaaggcaa
    47281 attggatgtg aatacaacta catcactgac tcaagagcaa atagataagt atattgcata
    47341 tgctgaagct ggtgttggta taggtcatgc agtcgcatat ccttttggag ttttaatagt
    47401 aatcttaggt gtaaatttcc ttccaaaatt atttaggatg gacctaaaag aagaaagaag
    47461 aaaatatgag aaggaaatga aggaagcaag agatagtgtt tctggtaaaa cgataccaga
    47521 agttccattt aatataataa catttttctt gacatgttta gctggatact tagttggagg
    47581 aatacatgta tttatgggac cactagggta cttcacacta ggtgcaacag gaggttcact
    47641 aattgtatct ctagttcttg gatatatagg taagataggg gtagtaaatt tcagaatgga
    47701 agaaaaggtt ttaaatattt taaaacaaat agggctagta tttttcttag caatagttgg
    47761 attaagatat ggtggaaaag tagttgattc aattatgaca tctggtatgc acctagcctt
    47821 agtagcaata gcagtaggtg ttacagctat gatgatagga ttcttagttg gcaaatacgt
    47881 atttaaatta aattggattt tattatctgg agctgtctgt ggtggtatga catcaacacc
    47941 aggtcttgga gctgctgttg atgctcttga tagtgatgac ccagcagcag gttatggtgc
    48001 tacgtatcca tttgcattat taactaaagt tatattggtt atagttttac acaaacttcc
    48061 aatgtaaata agattttata tggggggata tttatgaata atgaaggagc atttgaagaa
    48121 ttaagtggaa gattaagaaa taaagaattg tgtgatttaa taatgaatgc agatgaagct
    48181 gctaaaatta tagaggatgg catggttatt ggagttagtg gatttacacc ttcaggctat
    48241 ccaaaagcag taccattagc agtttcagaa agagctaaaa gtggagaaaa gataaaatta
    48301 accgtatatt caggagcatc tttaggtcca gaagttgatg gagcatggtc agaagcaggt
    48361 ataattgaaa gaagacttcc ttatcaaact aattcaatac ttagaaataa tattaataaa
    48421 ggtgttgttg attatataga tatgcaccta agtcattcta ctcaattttt aaattatgga
    48481 actataccta aagtagatgt agctatagta gaagcacttg caataactga agaaggaaat
    48541 attataccaa ctagtgggat aggtaattct ccatctttta taaaaagtgc agataaagta
    48601 atagtagaga taaatcttgc aaaaccaatg gaaatggaag gtatggcaga tatatatatt
    48661 acggaaaatc caccaaatag aaaaccaata gaaataaatc atcctaagga tagaattgga
    48721 acaacatata taccttgtgg tttggataaa attgcaggag tagtaattac caatatgcaa
    48781 gataagaccc gtccattggg agttgtagat gaagcttcga aaaaaatatc aaataatatt
    48841 attgcttttt taagagaaga agtaaaggca ggcagattat caaagaattt acttcctctt
    48901 caatctggtg taggaagtgt agcaaatgca gtattatatg gattatgtga atctgaattt
    48961 gaaaatttaa cttgttatac agaggttgta caggactcta tgttggattt aataagaatg
    49021 ggtaaagtta caatggcatc tactacatct gtaagtccat ctccagaagg attaataaaa
    49081 tttgaaaaag atattgattt ttttaaggat aagattatat taagacctca agaaattagt
    49141 aacaatccag aaatagccag aagaattggt gtaattgcaa tgaacactgc aattgaagtt
    49201 gatatttatg gaaatgtaaa ttctactcac ataatggggt caaagatgat gaatggaatt
    49261 ggtggttctg gtgattttgc tagaaatgga gcaataacta tatttagtac tgagtcaatt
    49321 gcaaaaaatg gtgatatatc atcaatagta cctatggtat ctcacgtaga ccacactgaa
    49381 catgatgtaa tggtaattgt aacagaacaa ggatatgctg atttaagagg tcttgcacct
    49441 agagaaagag ctataaaaat aatagaaaat tgtgcccatc cagattataa agaacaactt
    49501 agggattatt taaatagagc ttgtaaaagt ggagcaaaac aaacacctca catattggac
    49561 gaagctttat catggcatag taaatttatg agtacaggta caatgaaaaa ggctgaaact
    49621 tttaaaagtg cattataaaa tatttaataa attggaggta gattttaaat ggaaaaagca
    49681 gtggaaaact ttgaagattt aagtaaggaa tacattaatg gttatattga gagagcaaga
    49741 aaagctcaaa gagagtttga atgttatact caagaacaag tagataaaat agtaaaaata
    49801 gttggaaaag tagtgtatta taatgctgaa tatttagcta aacttgctgt agaagagact
    49861 ggaatgggag tatatgaaga taaggtagct aaaaataaaa gcaaagcaaa agttatatat
    49921 aacaatttaa aagataaaaa atcagttggt ataattgata tagatagaga aactggaata
    49981 acaaaggtag ctaaaccagt tggagtagta gcggcaataa ctccttgtac aaatccaatc
    50041 gttacaccta tgagcaatgc aatgtttgca cttaagggaa gaaatgcaat tattatcaca
    50101 cctcatcata aagcaattgg atgtagtaca aaaactgtag agatgattaa tgaagaatta
    50161 gaaaaaatag gagctccaga aaatttaata caaatacttg accaacaatc aagagaaaat
    50221 acaagaaatt taatttcatc agcagatgta gtaattgcca ctggaggaat gggaatggta
    50281 aaagctgcgt actcaagtgg aaaaccagca cttggtgtag gggcaggaaa tgttcaatgt
    50341 atcatagata gagatgtaga cattaaagaa gcagtaccta aaatcatagc aggaagaatt
    50401 tttgataatg gtatcatttg ttcaggtgaa cagtcagtaa tagtagcaga agaaatgttt
    50461 gataaaataa tggatgaatt taaaaataat aaaggtttta tagttagaga taaagtacaa
    50521 aaagaagctt tcagaaatgc tatgtttgta aataaatcta tgaataaaga tgcagtaggt
    50581 caatcagttc atacaattgc aaaaattgca ggtgttgaga taccagaaga tacaaaaata
    50641 atagtaatag aagctgatgg accaggagaa gaggatatta ttgcaaaaga aaaaatgtgt
    50701 ccagttatat ctgcatacaa gtataaaagt tttgaagaag gtgtagctat tgcaaaagca
    50761 aatttaaatg tagaaggaaa aggacatagt gtatctatac attcaaatac agttaaaaat
    50821 atagaatatg caggagaaaa tatagaagta tcaagatttg ttattaatca atgttgtgct
    50881 actagtgctg gaggaagttt ctttaatggt cttgcaccta ctaatactct aggttgtggt
    50941 tcttggggaa ataacagcat ctctgaaaat cttgattata agcatctaat taatatttct
    51001 agaattgctt attatatgcc agaaaatgaa gtccctacag atgaagaact ttggggataa
    51061 aatttagaca aaaaatattc attctaaatt aaagtaggaa tatattttaa tttagaatga
    51121 atttaagaca taaattaaat ttaaattagt ttattggact aaatttaaaa tattaagaga
    51181 catatagaag aaggaagtat tataatttaa aataaataaa aaaatctata aaagagaagg
    51241 agtggtttta ttatggcatt aatgacagga gctcaatata ttgaaagttt gagaaaatta
    51301 aatactaagg tttatatgtt tggtgaagag gttaagaatt gggttgacca tcctatgatt
    51361 agaccatcta taaattgtgt agcagcaact tatgacttag ctcatgaccc agaatatgca
    51421 gatttaatga cagttacttc aaatatcaca ggtgaaaaaa taaatagatt tggtcatctt
    51481 catcaaagtg ttgatgattt gataaaaaaa gtaaaaatgc aaagactatg tggtcaaaaa
    51541 acagcttctt gtttccaaag atgtgttggt atggatgcgt ttaatgcagt gtattcaaca
    51601 acatttgagt gtgataaagc ccatggaact aattatcatg ataattttgt aaaatactta
    51661 acttatatac aagaaaacga tttagtagtt gatggagcta tgactgaccc taagggagat
    51721 agaagtctat cacctagtgc tcaacctgac ccagatatgt tccttcatat agtagaaaga
    51781 agagaagatg ggataattgt aagaggagca aaggcacatc aaactggttc aataaattca
    51841 catgagcacc ttataatgcc tactataagt atgactgaag cagataaaga ctacgctgta
    51901 tcatttgcag ttccttcaga tgctgaagga gtgtttatga tttatggaag acaatcttgt
    51961 gacactagaa aattagaaga aggtgcagat gttgatttag gaaataagga gtttggaggt
    52021 caagaagctt tagtagtatt tgataatgta tttgttccaa atgatagaat tttcttatgt
    52081 ggagaatggg atttctctgg tatgttagta gagagatttg caggatacca tagacaaagt
    52141 tatggtggat gtaaagtagg agtaggtgat gtaataatag gagcagcagc tttagcagct
    52201 gattataatg gagcaaacaa agcttcacat ataaaagata aactaataga aatgactcac
    52261 cttaatgaaa gcttatattg ctgtggtata gcatgttcat cagaaggtca caaaacagaa
    52321 gctggaaact atcaaataga tttacttctt gcaaatgtgt gtaaacaaaa tgtaactaga
    52381 tttccttatg aaatagtaag acttgcagaa gatatagctg gagggcttat ggttactatg
    52441 ccttcagaaa aagactttaa atcagacctt aaagttggaa caagtggaat gactattggc
    52501 gaagtatgta acaagtattt taaagcttct tcagtggctt caacagaaga aagaatgaga
    52561 atattaagat tcttagaaaa tatatgcctt ggttcatctg ctgttggtta tagaactgag
    52621 tcaatgcatg gggcaggttc accacaagct caaagaataa tgatttcaag acaaggaaac
    52681 ataaatcaaa agaaagaatt agctaagaaa attgcgggaa taaaaaaaga ggaagcttta
    52741 aatttataaa aagttgatat ataaagggaa attatatatt aatgtgtatt aattaatgaa
    52801 aaaatatgta gtataagaga tagttataaa attatggtgg tttttagcta agtaaagaaa
    52861 tttttaataa ggagaattta cacatgacct gtggagttag attttgtggg ggctgtaacc
    52921 ctagatacga aagagggaag gctcttacaa taatcaaaga gcacttcaat ggtagggtag
    52981 attttagtat agcacaagag aacgtcgagt atgatttgct acttataatt ggaggatgcg
    53041 caactctatg cgcatcctat caacaatata aagtgaaaaa tgaatgtgtt aagatgtggg
    53101 attttagcca tatagaaaga gttataaatg tgattgaatc agcaatttgt gaaacttaaa
    53161 aaagctaaat ggggggattt cattgagttg gcaagaattg tatcaaagta aattatgtag
    53221 tgctacagaa gctgtaaaac agattaaaaa cggtgatact gtagtatttg cacattgtgt
    53281 aggtgaacct cctgcactag tagaggctat gattgaaaat gctgaacaat ataaagatgt
    53341 tgagattaaa catatggtaa gcttgggtag tggtggatat actgctaagg gaatggaagc
    53401 tcattttaga gtaaatccaa tgtttgtaag tggaaatgta agaaaggcaa ttgaaaatgg
    53461 agatggtgat tttacacctg cattcttcca tgaagtacca aagttgctta gagaaaaaag
    53521 attaaaatgt gatgttgttt tagcacaggt aactccacca gatgaacatg ggtattgtag
    53581 cttaggaaca tcagttgatt atacttatga agccattaaa actgctagaa cagtaattgt
    53641 tcaagtgaat gaccagtttc ctagaaccta tggtgaggta gtccatgtat cagagtttga
    53701 ctatatagtg gaaaaatcac aacctttatt tgaactacaa cctgcaaaga ttggagaagt
    53761 agaagaagca attggtaaaa attgtgcttc attaattgaa gatggttcta ctttacagct
    53821 agggattggt gggataccag atgcagttat gttattttta actgataaaa aggatttagg
    53881 gattcattca gaaatgattt cagatgggac tttggccctt tatgaaaaag gtgttataaa
    53941 tggtaaatat aaaaattttg ataaagaaaa aatgacagtt accttcttaa tgggtactaa
    54001 aaaattatat gactttgcaa ataataaccc tgcagtagag gtaaaaccag tagactatgt
    54061 gaatcatcca gcaattataa tgaaacaaca taagatggtt tctataaatt ctgctataca
    54121 agttgattta atgggacagg tagttgcaga ggctatggga cttagacaat ttagtggtgt
    54181 tggaggtcaa gttgacttta tacgtggagt gtctatgggt gaagatggaa aggcaattat
    54241 agctatgcct tcaataacta cgaaaaaaga tggtacagta atttcaaaaa tcgtgtctat
    54301 tgtggatgaa ggtgcaccta taacgacatc aagaaatgat gttgactata ttgtaacaga
    54361 atacggtata gcagaattaa aaggaaaatc tcttagagaa agagcgagaa atttaataaa
    54421 tatagctcat ccaagtgtaa gagaaagtct agcagtagaa tttgaaaaga gatttaagga
    54481 gaaatattaa taatagaggg gtgttaataa tggaagcact tagagtagtt ccaaagatat
    54541 tttactttga tacatttaaa gaatttaatg aagaatttaa aataggaaaa aatgatttag
    54601 taattactaa tgagtttata tatgagccat atatgaaacc tcttggaata gatacaaatt
    54661 taatttttca agaaaagttt ggaacaggtg aaccatctga tgaaatgata gactccatga
    54721 caaaggaaat gaagaaatac aattttgata gaattattgc atttggagga ggaacaatag
    54781 ttgatatatg taagatatta gcacttgatg ttccagaaaa gtctattgat ttatttgaag
    54841 gagaagtatc acctaaaaaa gtaaaagagt tagtagtagt tcctacaaca tgtggtacag
    54901 gtagtgaagt aacaaatgta gctattgcag agttaaaatc taaacatact aaaaaggggc
    54961 ttgcagtaga agaaacatat gcagactatg cagtgttaat tccagagaca gtaaaagggt
    55021 taccttacaa attctttgtt acaagttcgg tagatgctct tatacatgct attgagtctt
    55081 atctttctcc aaaagcaagt ccatttacag agatgtattc tctacaagca ataaaaatga
    55141 ttatggatgg gtataagaag atagttgata aaggagaaga agagagattt aatcatctta
    55201 gagactttgt acttgcatca aattatgcag gaattgcttt tggaaatgct ggttgtgcag
    55261 cagttcatgc actatcttat tcaataggtg gagctttcca tgttgcacat ggtgaagcaa
    55321 attatcagtt ctttactgaa gtatttaaga tgtattctag aaaaaaacct aatggaaaaa
    55381 ttataaaatg tacaaaaatt ttagcagatg cccttgaatg tgaccctaac tgtgatgttt
    55441 atggagaatt agaaaagttt ttaaataaat taatagctaa aaaagctttg agagaatatg
    55501 gaatggtgga aagtcagata gatgaattta cagatagtac aatagcaaat caacaacgac
    55561 tacttgctaa taattatgta gagcttagta gagaggaaat aagagagata tttgcaaatc
    55621 tttattaata caatttttta tttatatgta tagtcaacat aaacaatgct aattatattt
    55681 atgtacaaat aaaaataagg gaacttaaat tttaattaaa gttaagttct cttattttta
    55741 tatggagtta aatataagta tatttttaat ttaaaatatg cttatattta agtctattac
    55801 tttatttgaa acaatttgta gaatttcaaa ttccttgaca gtaataagta agtaattgta
    55861 taatcaaact gcaatatatt aataatatta gtgaaaatga aaggattata aaatatgtat
    55921 aaatcagaaa atttttcaaa aaaatctgta ttaataaatt catttttaag taaattttta
    55981 aaaataattg gatggggttt ggtaagctta tttacattat cagccttagt actttcaact
    56041 atttccatta taattggatg ggctgtaata cttcctattc aagtatgtgc agtattttta
    56101 cttataggag gagtttgtat ttttaaaggt aagagattag gagaccaaat ttctcgttat
    56161 aaaaaatatt gtacaattat aaacaataga aatattattc cagtagaact tattgcagaa
    56221 aacacatcta aatcattaaa ttttataata aaagatgtac aaaagatgat agacaaaaac
    56281 tactttataa atacttatat tgataaaaga aataatcaga ttgtgttaac aaatgaagat
    56341 tttgttccac caagatatga agatgtagca tatgaagtca aagaagaaga aaagactgat
    56401 gaatccaatg aagttgatac aattataaat aaaggaatga attatctaac acaaataaaa
    56461 gaagctaata aaaatattaa atcagaatca atgggcgata aaattgtaca agtagaagat
    56521 gttacaagta aaatatttga tgttgtaaaa catgacccat caaaacttac tcagatacaa
    56581 aaatttatgg attattatct tccaaccact ttaaaactat taaattcata tcatacattg
    56641 gaagaacaag gaattgatag agaaaatata acaacaacta tggaaagtat tgaaaataca
    56701 atgaatacga ttgtagtagc ttttgaaaat caattggact atctgtttga agatgaagcc
    56761 attgatattt ctacagatat tactgtttta gagaatatgt tagtccaaga aggattaacg
    56821 agtggtaaat tttaacttca atagaaaaaa tattctgtta tttttaaaca attaattagt
    56881 cataaagtat aaaatgtgta ttatataagt taatcagtac tttatgaagg aagaggagag
    56941 aaagatacaa tgaataattt agatgatata ccagttatgc caactttgac acttgaccca
    57001 tttggagaag aatcaaacac taatgatata gataattctg acttattaat gaaaaaggat
    57061 gaaaaagacc cagaagaaga aaaactgtct gaatctgaac gcaagatggt aaaggaattt
    57121 gcggaaaaaa tagatattac aaatacaaat atgattttgc aatatggagc tggagctcaa
    57181 aaaaaggtag caagtttttc tgaaacagct ttaaagagtg taaaaacaag agatttagga
    57241 gaagttggag atatgcttac aaatctagtt actgatttaa aagcattttc agcagatgaa
    57301 aaagaacaaa gtggtttttt aggaattttt aaaaaggcaa ataataaaat ttcaaattta
    57361 aaaactaagt atgatagtgc agaggtaaat gtggataaag taagcaaaga gcttcaaaag
    57421 catcaggtta aaatattgaa agatatagca atgcttgata agatgtatga attgaactta
    57481 gcttactcaa aagagcttac tatgtatatt atagcaggaa aacaaaaatt aaaggatatg
    57541 aaagaatatg aaatgccaaa gttgagagaa aaagctcgtt tatctggttc aacagaagat
    57601 gctcaatctg taaatgatat ggtttcactt tgtgacagat ttgaaaagaa gattcatgac
    57661 ttagaattaa ctagaatggt atcgcttcaa atggctcctc agataagatt ggttcaaaat
    57721 agtaataatc tgatggcaga aaagattcaa tcaactatag taaataccat tccattatgg
    57781 aaaaatcaaa tagtgcttgc tcttggaatt tctcacttaa atcaagctat gaaagcacag
    57841 cgtgaagtta gtaatatgac aaatgagctt ttattaaaga atgcagaaac tttgaagatg
    57901 ggaacaatag aaacagcaaa agaatcagaa agaggaattg tagatataga cacaattaag
    57961 aaaactaatc aatctctaat atctactatt gatgaggtag ttaaaataca acatgatggt
    58021 agaataaaga gacaagaagc agaagttgaa ttatcaaaaa tagaaaatga acttaaaagt
    58081 aagcttcttg aatttacagt taaataaaaa ttatactaat ataaaaagag actgtctcaa
    58141 aatagagata agtctctttt tcattgttta aatgattaaa gtatatttat attataaatt
    58201 tctattatct tttaacataa catcatgagc tccaccttca actatactag tagaagatac
    58261 aagtgtaagt ttagcatttt tttgaagttc aggaatgcta agtgctccac agttacacat
    58321 agtagaacga actttactta aagaaagagt tacattgtct ttcaaagaac cagcataagg
    58381 cacataagag tcaacacctt cttcaaaaga aagtttctta tctccaccaa ggtcatatct
    58441 ttgccagttt ctagcacgag cagaaccttc tccccaatac tctttcatat aactaccatt
    58501 tatattaact ttgttagttg gactctcatc aaaacgagag aagtatctac caagcattat
    58561 aaaatctgca cccatagcta aagctaaagt tatatgatgg tcataaacga taccaccatc
    58621 agagcaaatt ggaatataaa tacctgtttt ttcaaagtat tcgtctctag cttgagcaac
    58681 ttcaattata gaagtagctt gtccacgtcc tatacctttt tgttcacgag ttatacatat
    58741 agaaccacca ccaataccaa ctttaacgaa gtcagcacca gcttcagcta ggtaaaggaa
    58801 tccttcgcgg tcaactacat ttccagctcc taccttaact gtatcaccat atttttcacg
    58861 aatgaaatca agtgttattt tttgccactc agaaaaacct tctgaagaat ctatacataa
    58921 aacatcagca ccagcttcaa ctaaagcagg aacacgttca gcaaagtctc tagtattaat
    58981 accagctcca actacatatc tcttagaaga atctaaaagt tcaagtggat tttctttatg
    59041 agaagagtaa tctttacgga ataccatata cataagatta ccattatcat caagtacagg
    59101 aagagaatta agtttgtggt cccatataat attgtttgct tcctttaaag taacatcttt
    59161 gttagcataa actatagatg acataggagt cataaattca ctaactttag tatctaaatc
    59221 catacgactt atacgataat cacgacttgc aacaataccc aataatttac cagttgaagt
    59281 tccatcttca gtaacagcta ctgtagaatg tccagttttt tcttttaagt caagtatgtc
    59341 ttttaatgtg ttatcaggtt taatatttga atcacttaca acaaaaccag ctttgtggga
    59401 tttaacacgt gctaccatag cagcttcatt ttcaatagtt tgagaaccgt atataaatga
    59461 aataccacct tctttagcaa gtgcaatagc cattttgtca tcagaaacag attgcataat
    59521 agcagaagtc aaaggtatat tcatataaat atctgcttcc tcgccctttt taaatttagt
    59581 aacaggtgtt tttaaactta cattagcagg tatacaatca gtagaagaga aacctggtac
    59641 aagaaggtat tcactgaaag tatgtgatgg tgtatcaaaa taaaacgcca ttttttaatc
    59701 actccttata tttttatact ttttataatt gatagtatta attataactt attctttaat
    59761 tttattaaag tattttgtca aatattgaga tttttgaaaa atttaaacta ttttaattaa
    59821 atttgtttaa tatatattgc cttatagggt aaagttgtat attaaataat gtttagtgtt
    59881 taatagtagc taatttaaaa ttaatcttta gtgattcata taattacatt tgtatagttt
    59941 acattgataa tattactaga gagtgtataa acctcaaaaa tacagataaa ttaaatctat
    60001 attagtatat ccaaaagtac atttaataaa tttatttaac tgaattatta ttttcatttc
    60061 tattaaattt aaatatttta taaaaatagt attatttaca aaatcatata ctccaaaata
    60121 ctacataaat aaaattaaac aaaaactaaa atgacaaatg tcattatcta aagtgacata
    60181 gaaacggttt cttaaagttg ttactataaa atataaactc tataataaaa gtataacaaa
    60241 agggaatcat atcgatatag aatataattc aagaggaggt aaaattatga gtagttctaa
    60301 tcaatcgaca ataaagacat ctatacagcg agtagggaaa tttttaagtg gtatggtaat
    60361 gccaaatata ggagctttta tagcatgggg tcttataaca gcattattta taccaacagg
    60421 atggatgcct aatgaaaaat tgagtactat aggtgaccca atgataaaat accttttacc
    60481 actattgata gcttatactg gtggtaaagc aatagcagga caaagaggtg gcgtaatagg
    60541 tgcagcagca gctatgggag taattgttgg tgcagatata ccaatgttta tcggagcaat
    60601 gataatggga ccatttgcag gatgggtaat taagaagttt gataaatttg tagatggaaa
    60661 gataccaaca ggatttgaaa tgttagtaaa taacttttca ataggtataa taggtatgct
    60721 tcttgcaata ctaggatttt atgcaattgg accagcaata gtagcaggaa cagctcttat
    60781 agaatctgga gttcaattta tagttagcaa aagtttattg cctctagttt cagtatttat
    60841 agaacctgga aaagtattat tcttaaacaa tgcaataaat catggtatat tagggcctat
    60901 aggtatagct gaggcaaaag aagcaggtaa atctataatg ttcttactag aaagtaaccc
    60961 tggaccaggt ttaggagttc tattagcata ttggatgttt agtagaggaa gtgtaaaaca
    61021 atcagcacca ggagctgtaa taatacattt ctttggtggt atccatgaaa tttacttccc
    61081 atatatttta atgaatccag ttttaatatt agctacaatg gcaggtggag cagcaggaat
    61141 attgactttt tcaatattag gagctgggct tgtagcagca ccatcaccag gaagtatatt
    61201 tgcacttatg gcactagctc caaagggagg attacttcca gtattagcag gagttgcagt
    61261 ggcaacagtt gtatcattct tagtggcagc accatttgtt aagagagctt cagcaaatca
    61321 aagtgaagaa gacagtactt ctttagaaga agctaaagca aaaatgagtg atatgaaatc
    61381 tgcaagtaag aactctgaga aaaatattga ggaaaaacag cttgaagtaa atgagattaa
    61441 gaagattgta tttgcatgtg atgcaggaat gggttcgagt gcaatgggag cttccagatt
    61501 taaaaataga ataaaaaact tagacttaaa tatagaaatt acaaattcat ctgttgataa
    61561 tcttccagat gatacacaaa tagtagtaac tcacaataca ttagttgaaa gagttgctaa
    61621 gaataattca agtgttgaga tagtttcaat aaacaatttt ttaaatgacc caaatttaga
    61681 tacattgttt aaaagattag aatctaaata aaaataaaaa gtaccactaa ttaggagtgg
    61741 ataatttgaa aaaaaagaag attacatcta ggcaaaaaaa gataatacta atgatagtag
    61801 aaaattcaaa gaaaaacatt ccaataacta tttctgagat tgcagggact ttagagttaa
    61861 gttcaagaac tgtacttaga gatatgtctg gaattgaaaa atggtttgat gaaaatgatt
    61921 ttaactttgt aaaaaaacca ggagtgggat tgattttaga ggaaaatata gaaaatcaaa
    61981 actttataat tgagttgtta gaagaagaaa aaatagaaaa agaatacagc aaggaagaaa
    62041 gaaatttaat tatattatca aagctactag tttctaacga gccagtaaaa tcctattatt
    62101 ttgcaaaaat attaaaggta tctgaagggg tactgaataa tgattttgcc ttagcaagta
    62161 aatggttgga aagatttgat attgagcttg ttagaaaacc agggcttggt gtctatttaa
    62221 aaggtcaaga aaaaagcttt agagaggcat atgtaaatct tatatacgat tcattcaatg
    62281 aaaaagaaat actagatatg gtcagaaata taagtgaaaa tatacaaaca gataaagcaa
    62341 tagaaatttt aagtgaaaat agacttttaa atttaatgga caggtgcata ataagaaagg
    62401 ttgaagctac attaacaaag aagctttcag atttagatgt aaatttagct gatagtgcat
    62461 atatagggct tgtagttcat atttcattag ccttacagag gataaaaaat ggtgaaaata
    62521 taactatgga taaagagttt ctaaaagaat tatctataac agaagagttt aaattagcta
    62581 aagaaatcgt aaaaggtatg gaaacagatt ttaacatgga tataccagta gatgaggttg
    62641 gatatataac tatgcatata agaggtgcaa agcaaaggtc atcttcaaac cataaggctt
    62701 taaacttaga tgatatagaa ataatggaaa ttacaaataa gatgatagat ttggcggaag
    62761 atgaatttaa aataagttta aaaaatgacg agaggttatt taaagaccta gcaaatcact
    62821 tagggccttc tataaataga ttgaatatgg gattagaaat aagaaatcct cttttagatg
    62881 aaataaaaag caagtattca tatgcctatg atggagttga aaagatttct agaattataa
    62941 aagataaact aaatataaat tcaatacctg aatcagaaat aggatatatt gcaatgcact
    63001 ttgcatcagc catagaaaaa aatcttatga tgaatactaa tataaatatt gttgtggcat
    63061 gtcccactgg aataggtact tcaagattct tatcaactaa gattgaaaat aaatttccta
    63121 atttaaatat acttgaaacc atatcagcta taaacataga tgaagagtat ttaaaggaaa
    63181 aagatgttga tttaatagtg tctacagttg agttaaatac aagtttaaat tatatatgtg
    63241 taggtccatt tatgagttta gatgatgaac agataatcaa ggaaaaaata aaatctatag
    63301 ctcaaaataa attaatcaat ttaaatgcga aaaatgatac taagagtaag aataaagtat
    63361 atgaacagat aacagaaagt atgaatatag gaaaagatat tcttcaattt ttagaggaaa
    63421 ttagatttga aaaatttgaa agtaaagatt taagtgagct tattgaagac tcatcaaaaa
    63481 tatttgcaaa atctagtgaa gatataatct ctataaaaga atcgttaaaa gaaagattaa
    63541 aaatttcaat tccatatata gaagaatcaa aaattctatt gttacattgt atgagtgaaa
    63601 gaatagatat tatgaagtta tcaataataa aactagagaa tagaatcgtg ctagattcaa
    63661 atgaagaaat cgacaatgta gtttttatgt tacttcctaa aaattcacca agttatcaaa
    63721 gacaaataat gagtgaaata agtggttcat taatagacaa tataattttt actaataaga
    63781 taaataaatt ctctatagaa gagatggcat tagaggtaaa agatatagtt tttaattttt
    63841 atacaaacag attaaaagca tttatagata aataaaatta atattaaaaa ggaaggttga
    63901 tactatgagt aaagtattga atgagaataa tatattttta ggattagata gtgtttcaaa
    63961 ggaagaagct ataactttag caggaagaaa attagttgaa aatggatatg taaaagaaga
    64021 atatatacca gcaatgttag aaagagaaaa agtaatgact acatatatgg gaatgggagt
    64081 tgctattcca catggtgtaa atgaagcaaa aaaagaaata ttatcttctg gaatagttat
    64141 attacaattc cctaatggta tagattttga tggagaaaaa gcatatttat taataggaat
    64201 agctggtgtt ggagatgaac atttagaaat actatctaat atagcagtag ttttagatga
    64261 tgacttaaca gaaagactaa aaaattcaaa tgacaaacaa gcttttatgg aagcttttgc
    64321 caactaatct taggagggat ttaaaatgaa aaaggcaatt cagtttggag caggaaatat
    64381 tggaagaggt tttattggag gcttgttagt taagtcgggt tatcatgtag tatttgctga
    64441 tgtaaatgag gggatattaa actcaataaa caaagataaa aagtatacta tacacataag
    64501 agatgtagaa tgtatagatg aagtaattga taatataagt gcggtttcat ctataaaaga
    64561 agaaataata gatgagattg tacaggctga aataataact acagcagttg gacctttagt
    64621 tttgactaaa atagcctcta caattgcaaa aggtataaag gctagaaaag aaaagggatt
    64681 aacaagtaat ctaaatataa tagcatgtga aaatgcaata tacgcaagtt cttctttaaa
    64741 agaagaggta cttaagtatt taaataagga agaagtagaa tatttagaga tgtatgttgg
    64801 ttttccaaac tgttcagttg atagaatagt tcctcctggt aaaaacgaaa atcctcttga
    64861 tgtaacagtt gaaaattttt atgagtggaa tgttgaaaaa caaggattta aaggggaaat
    64921 accaactata gttggaatga atttagctga taatcttatg gcttatatag aacgtaaatt
    64981 gtttacactg aatacaggtc atgctataac agcttatata ggatatttaa aaggatataa
    65041 gactatagaa gagagtataa aagataaatt tatctgtgat atagtcaaaa gtgcaatggt
    65101 agaaagtgga gaaggattga ttaaaaaata caattttgac tcagaagtgc actataaata
    65161 tattgataaa attttaaata gatttaaaaa tccatatctt aatgatgatg tattaagagt
    65221 cggaagggaa ccattaagaa aactaagtga taaagataga ttgattaaac ctttaatgac
    65281 agcaaaatca tatggattat cagttgataa tttgattctt ggaataggtg cagcgcttca
    65341 ttataataat agtgaagata ctcaaagtgt agaattacaa gagttgataa agtctattgg
    65401 ggtaaaaaaa gccgttgcta aaatagctaa tataagcaat gacgaagaac ttttaaataa
    65461 tatcgaaaaa agttatatat ttatgaaaaa tttataaatt tacttgaaaa aaagtagttc
    65521 tgataaagta actataatat attattctac acagtttgaa ttatttgttg aataatagag
    65581 aattataata tataattaaa aggaataaat taatatattt acctgtatat gtttgataat
    65641 atggttcaaa tgtttctact aagctaccat taatagcttg actacaggag tgaagaagat
    65701 atagtttata cttattttaa attatatatt aagttaatta ctttgaattt taagctcctg
    65761 tctatgatat agacaggagc ttttttagta ttttaatata aaatacttac aagaatagat
    65821 agcaaaatta gaacaaatat aattttttta ttaatataat tttagaaagg gctaggtgga
    65881 agttcaatga aggctttaca agaaaagata ttgagagaag gtagtgtttc aggaaatgat
    65941 atactaaaag ttgatagttt tttaaaccat caaattgatg tagctttttt aaatgaaata
    66001 ggaagagaat ttaaagagag atttaaagga gaaaaggtgg ataagatatt tacaatagag
    66061 gcttcaggaa tagctatagc atcaattgtt tcacagtatt ttgataatgc acctgtagta
    66121 tttgcaaaaa aatcagaatc taaaaatttg gataaagatg tatatgaaac taatgtatat
    66181 tcatttacta aggcaagaga gtattcagtt aaagtttcta aaaagtacat aaacaaaggc
    66241 gaaaatatat tgatagtgga tgattttttg gcaaatggaa gagctgctct tggacttaaa
    66301 gatttaattg agcaagcaga agctaactta gttggagtag gaattgtcat tgaaaaagga
    66361 tttcaagctg gaggagcact tttaaaggct aatgatgtaa gattagagtc tttggcagta
    66421 gttgaatcta tagataatgg aactgtaaaa tttaggtaat ttatgatatt atatatttgt
    66481 gtttagcaca tattttaact atgtaattat ggaggatttt ttatgagatt ttttatagac
    66541 acagccaata ttgaagaaat aaaagaagca aatgatttag gtgtaatctg tggtgtaact
    66601 actaatccgt ctctaatagc taaagaaggt agagatttta tagaggtagt taaagaaata
    66661 agtgaaatag tagatggacc aataagtgca gaagtaataa gtttagaaca taaaggtatg
    66721 atagaggaag cagaaaaatt atctaagata cataaaaata tagttataaa gatacctatg
    66781 acagcagaag gtctaaaagc ggtgaaagta ctatcaagta aaggtataaa gactaatgta
    66841 acgcttatat tctctgctgg acaagctctt ttagctgcta gagctggagc tacatatgta
    66901 agtccttttg ttggtagatt ggatgatata tcacaaaatg gtcttgattt aattgaagaa
    66961 atcgttgata tatttagtgt aaatagtatt gaggctcaaa taatagttgc tagtgttaga
    67021 aatccaatac atgttttaca agctgctaga atgggagcag atatagcaac agttcctctt
    67081 aaagttataa accaaatgat taagcatcct ttgacagaca aaggaataga tagctttatg
    67141 aaggattggg aaggtgcttc tttaaaatta taattataaa ctacgcttta taagtatatt
    67201 aaagaggtta ttatggaaat tctaagtaat aaggctaggc tattttgcct agtcttattt
    67261 tggtgtataa tatattgaaa catattattg aaatagatta attttttaag tgaggaggcg
    67321 aaaaatggat aaaatattaa gagagataca aagagaagat aaaaaaaatc catatactga
    67381 ccaagaactt gctgaaatgt taaatgtagc taggtctgaa gtgatatcag ttaggaaaaa
    67441 aaataatatt ttagattcga gagaaagaag aaaaaaaata ttaataaaag atatatcaaa
    67501 aattgtaagt gaaaatcctc aaatgtctga aagaaaaata actgaaatat taatagaaaa
    67561 tggatataat atatcgagaa gtgcagtttc aaaattatta aaagaggaaa atttaaatca
    67621 gtcaaagatt gggattaagg ataaagaccc agcatcatca ggaaagtatg tgaaggtgag
    67681 taaagttgta gaagaagatg gatttgaaga attgataggt ataaagggaa gtttgaaaga
    67741 aaaggtaaat ttagctaagt cagcaataat gtatcctcct aatggccttc atactataat
    67801 atatggagaa acaggagtag gtaaaagtga attagctaca tgtatgtata aatatgctat
    67861 aaaaaacaac attaaagaag agaacagccc atttatagtg tttaactgtg cagactatgc
    67921 agaaaatcct aatctattga tagctcaact ctttggggta gtaaaaggtg catatacagg
    67981 agcagatgca aatagagaag gtcttgtaga acaagctaat aatggaatat tgtttttaga
    68041 tgaaattcat agattgcctg ctgctgggca agaaatctta ttttcattaa tagatagagg
    68101 agaatttaga aggttaggag aaagtagttc taatagaaag gcaaatgttc tcataataag
    68161 tgctacaaca gaaaatccag attctaattt acttcaaaca tttagaagac gtataccaat
    68221 ggtaataaat ttacctaata tgagtgaaag accaaaatct gaaagatatg aaataataat
    68281 aaagtttttt gaaagagaag caaagcgagt aaacaagaat tttataataa ctaaagaagt
    68341 tatgtgtgca cttatgaatt ataagtgtac tggaaatata ggtcagttaa agagtgatat
    68401 acaagtaact tgtgctagag cttttagtaa atcgatattt tctagtgata aagtaattat
    68461 agatttagat agtttaaggg attatataaa aagtggatat tatgattgta attgtaaaaa
    68521 tgaaaagtat tctgagtttt cagttgagga tatatatata gatattagtg aattggtgag
    68581 tggaaaaaat agaattttat ctgataatga gataagcgag atatataatt atgcagaaaa
    68641 agagcttaag gttttggaaa gtaagtgctt ttcagaagaa gagttaaaaa atgcatttat
    68701 agaaaagtta gataagaagt ttaatgctat taaaaacaat aaaaatttat ctgatagaag
    68761 aagtcgaata gactggggag gacaattaaa agagtctaca ctggagataa tggataaggt
    68821 aattgtattt attaaggagc agtttaagca tgtaaatcaa gggctgtact tggctctagc
    68881 aattcatatt gagcatgcta taggtaggat aaaagatgga aaaactataa taaatccgag
    68941 tttagataaa ataaaagcat caatgccaat ggaatatgag ttgtcaagat atataatggg
    69001 tatagtagaa gatttgacac aagtaacatt tccagaagat gagcttggat atttggctta
    69061 ttatataaat aaattttgtt ataatgagga aagtataaaa gataaagtta aagtagtaat
    69121 agttacgcat ggtaaagttg gaattgaaat gtctaaagtt gtaaatcata ttttaggtat
    69181 agaatgtaca ctaggtatag aaatagcact tacagattca ccatcagagg ggatagagca
    69241 tgtattagaa gagcttcaaa agatagaagc tagaaaaggt attctagttc taattgatat
    69301 gggttctttg gtaattcttg gtgatgaggt tgaaaaaagg cttggaatta gatgtaaaac
    69361 tgtaaataga gtagatacat tattggcaat ggaagcagga aaacttgcaa ccattgaagg
    69421 gaaaagttta gatggtataa tagctgattt aaagaaaaat aagaattatg ctatgataaa
    69481 tacaaataaa tttagttaca gaaaaaacga gtatggaaag aaaaatgtaa tcattacttt
    69541 atgtttgagt ggtgtaggta cagctttaaa tttaaaagag catatagaaa aacaaattaa
    69601 ggaatatgac actttaattg aagtaaagcc agttgctttt ttaaataata atttagaaga
    69661 agagttaaat gatattgaag ctgaatataa tattattgct atctgtggaa ctattgatat
    69721 agattataaa aacgtgcctt ttatttctta taatgaggta cttggtaaaa atggtattaa
    69781 taaagtatta gagcatttaa atagtaaaca accagcttta aatattgaaa accagttgaa
    69841 taatttaata catgaagatt tgattttata caattttgaa ggaatttcaa aggagtatat
    69901 aattgatact cttgtttcaa aacttgaaga aggtggatat gtcgactcaa agtatatatt
    69961 aagtgtatat aaaagagaag caatgggaag tgttgtaatg gcctctaagg tagccgtgcc
    70021 acatggactt ccagaaaacg ttataaagcc tgcaatagca attgcgaggt tgaataaacc
    70081 tatagtatgg gacaataaat ttatggtgga tttggtggta ctactggcac ttaaagaaaa
    70141 taataagaaa gaaatacgaa gcttattttc aaagattaat gaccagcata ctttagaagt
    70201 tttattaaat actgaagata aaaatgaaat aaaagaactt ttaagctaat tgttagtacc
    70261 gagaagaaag acaaaaaaat ttgctttagt agtataaaat ttaaaactac tcaattgcta
    70321 agtagttaat tactctatat aaggctagtt ctatgaaatt tatttatatg attttataga
    70381 attagctttt ttcttggtaa ataaaatata tgaatttatt tatgtaaaa
//
LOCUS       DAMKNB010000011        67565 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.011, whole genome shotgun sequence.
ACCESSION   DAMKNB010000011 DAMKNB010000000
VERSION     DAMKNB010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 67565)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 67565)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..67565
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.011"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            complement(414..1136)
                     /locus_tag="PC494_000860"
     CDS             complement(414..1136)
                     /locus_tag="PC494_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004398740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HDF3911382.1"
                     /translation="MITIKNLSKSFGDLNVLKNIDLEIAKGEIMVIVGPSGSGKSTLL
                     RCMNLLEIPTGGEIIFEGKNLVDKKTNIDEVRQNIGMVFQNFNLFPHKTILDNITLAP
                     IKLKKMTKEEAEKKAEILLSRVGLLDKKDSYPSQLSGGQKQRIAIARALAMEPDMMLF
                     DEPTSALDPEMVNEVLDVIKELAKEGMTMAIVTHEMGFAKEVADRVIFIDGGSILEDN
                     TPEEVFGNPKHERTKAFLAKVL"
     gene            complement(1195..1872)
                     /locus_tag="PC494_000861"
     CDS             complement(1195..1872)
                     /locus_tag="PC494_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HDF3911383.1"
                     /translation="MSLDFSFLSRFGTSFLEGTGVTVSISLVALCFGFIIGIIICMAK
                     ISKSKVLRAISSIYIEVLRGTPLLVQIYIVWFGLPQLGIRFPMLFGIPSEFIASAFAL
                     SVNSGAYVAEILRSGIQSVDNGQMEASRSLGLNYWSTMRYIIIPQAIKNILPSLANEF
                     ITLVKESSIISVIGVVEIMRTADIVKNAAFRALEPLIVAAAIYFVITFTLSRLVGLLE
                     KKLSVSN"
     gene            complement(1900..2715)
                     /locus_tag="PC494_000862"
     CDS             complement(1900..2715)
                     /locus_tag="PC494_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HDF3911384.1"
                     /translation="MKVFKKLLSLGLVLGLTLSLVGCSGGGEKTKLEQIKDNGKLVVG
                     TSAEFPPFEFHKVVDGKDSIKGFDIMLAEEFAKELGVKVEIKDMSFDGLIGALNADQV
                     DIVLAGMSPTPEREKSVDFSELYYLSRNAVIVKDADIDKVKTEDDLKKLRVGVQAGSI
                     QEEYVVNTLKMTTTKSLKAIPDLITELKNGNIDAVVTNEAVSLINVKKYDGIKMANTE
                     VGKDVTEGMAAAIKKSDNNKDFIELLNKKIKELQDGKKIEEFLNEASTEAASN"
     misc_binding    complement(2941..3151)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(3828..5894)
                     /locus_tag="PC494_000863"
     CDS             complement(3828..5894)
                     /locus_tag="PC494_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HDF3911385.1"
                     /translation="MVELIITTNIDIRKLNENQLEAVEHIDGPCMILAGPGSGKTRVI
                     TYRIANMVVNKNIAPTRILAISFTKASSIEMKNRALNLSDDIRLNKVTYGTFHSVFFK
                     ILRYFERYNLDSIFDEKSKRMTIKAILKSLNIENADDDENIGQVINEISYVKNELMDK
                     NEFNSEVLTKDEFLKVYNLYEEQKSKVNKIDFDDMLIRTYYLLLNNKSALEMVRNVYK
                     YILIDEFQDINKVQFEVLKLICSPLNNIFAVGDEDQSIYGFRGARPDFLLEFEQYFNN
                     TKKIILDINYRSKSEIVHTANRLIDKNKNRYEKIIKCSQGDGGSVTYISPHDSEEEAL
                     YIAREIIDEIQKDYVEYSDFAVIYRTNIQSRALVDVFMDMRIPFVVKDSVITIYDHWA
                     SQDILAYLRIGINPKSNKDWLRIINKPFRYISKDSINMVKDEKDFITALINKCNLHPK
                     QVKTINDLEIDLSYLNTLNPKNAISYIRTSLDYDRYVLDYCSNRKIKTNGLVEILNEL
                     ESSATNFNTVTEFLEHIDRVKTELTENNKNKQTEGVIFTTMHSAKGLEFRNVYIIGVN
                     EGTIPHEKSYDICKEEKKEEQLEEERRLMYVAITRAEEKLCISSTLNKYGKKVDKSLF
                     INDIKSPTKKEIDSIGVGDKVYHKKFHEGEIIKKDGIMFTIKFKDRERILDLKTCLLK
                     NIIYTI"
     gene            complement(5971..9000)
                     /locus_tag="PC494_000864"
     CDS             complement(5971..9000)
                     /locus_tag="PC494_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HDF3911386.1"
                     /translation="MENNLRKNNSIMKKMIFPLIIVMLIQTSLFCATILWGGTIKKLN
                     DNSFDILNERVINRKNYIQNEMLQRWSNTSETEATINSSVKKVLNEKNALIEDVGNNE
                     EINKDIIKSISNDLIYLLRKNSVTGAFIILSDKNINDKSIDSKGEISRTGLYIRDLDP
                     KFNPNDNSDLLIERGSSDIARSFGISMDSYWEPKFSFKSENEQDGDDFFYKPFRAAID
                     NPNVSSSNLGYWGSKFLLTNAGDRLMTYTVPLIYEDGTVYGVLGIDLSVNYLRELLPY
                     SEINGNKKGNYILGVDRNNDMAFENVISNGYSLKEKFWDGLHSNLEQKESYKNIYKIK
                     NKDNECGNGNIYASVQYLDLYNSNTPFENERWALLGIIEEKSLLSFSKRVEKLVIISI
                     AISLLIGLIGIYIASRLFTKPIVLLANKVRNSNPSKPVNLDKINISEIDELSSAIELL
                     SANVADSSSKLSQIIEMVDMPIGAFELYKNAENVFCTKEFFSVFTTEIKFEEYGYMEK
                     NKFLKKLRGLDKYLQESYETENTYIYKFESKDKKLKWIRMNIFEDELKVLGVVVDVTK
                     EFIEKRKIEYERDFDILTNLLNRRAFHSQIQEKFKNKDELKIAAFIMWDLDNLKYIND
                     TYGHDAGDEYIRCAADILKKFISWNGIVSRLSGDEFYVFIYGYESKDSIRDIINSVKK
                     QMNNTLLKLHDGTEFKIRASAGISWYPDDSTNYDELMRYADFAMYQIKNTIKGEVSEF
                     DINIYNKDSFLLSNREELNKLIDGQLVEYAFQPIVDCKGKVFAYEALMRPKIKTFSSP
                     IDVIRLARSQSKLYQIERITWFKALKSFKKYKEKFGDCKLFLNSIPNNNLSKVDFEEI
                     EDLYGEYLNRVVLEITENDKINEDFIEKKKAYIDHWNIEIALDDFGTGYNGDAVLLYI
                     MPDYVKIDMSIVRGIDKDENRQKILKNLISYSNERNIKVIAEGVETKGEMETLINLGV
                     DYMQGYYISKPSFIPEDISDKIKKELKICHENRNDVV"
     gene            complement(9053..10513)
                     /locus_tag="PC494_000865"
     CDS             complement(9053..10513)
                     /locus_tag="PC494_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HDF3911387.1"
                     /translation="MNRCKFAKLIITSMIVLLLTGCSLKKEDNYKLDPENPTSIQIWH
                     YYNGQQKMAFDKLVKEFNDTVGAEKGIIVEAFSQGNVVDLSEKVLDSANKKVGSEDVP
                     NIFAAYSDTAYEMDKLGLLVDMDKYISKEELNEYIDEYVEEGRINSKDEFKLFPIAKS
                     TEILMLNKTDWDKFAKATNSNINDIKTIEGLVETSKKYYEWTDSLTKEPNDGKAFFGR
                     DALANYIIIGSKQLGVEIFSVKDGKVTLNIDEKVMKKLWDNFYVPYINGYFASYGKFR
                     SDDAKTGDILALVGSSSGAAYFPDRVMLNDNESYNIETSVFQAPRFKGEGKYAVQQGA
                     GMAVTKSTKEEEYASVEFLKWFTDKEPNIKFSIASGYLPVKKKTNDLDVIKEVMKKDN
                     LSLSDKVEGSIASSIEQINSCNLYTNKAFDGGTKARQILEYSMLDKAKEDSNKINELV
                     KSGTSKKDAVAQFNNDKNFKTWFESFKAELENAIKK"
     gene            complement(10605..10979)
                     /locus_tag="PC494_000866"
     CDS             complement(10605..10979)
                     /locus_tag="PC494_000866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3911388.1"
                     /translation="MGNKNKNTKYKDKTRERYNKKVENLNKEKLNKVNKQSKKVDKID
                     DIINKSSIVLCVLLVVFSLLYLFKLVQLNIIMILLVITVAIQQGLVSFGAFRNKNYVK
                     ALFSIFVIVCFLIAFKYVVNPV"
     gene            complement(11155..11895)
                     /locus_tag="PC494_000867"
     CDS             complement(11155..11895)
                     /locus_tag="PC494_000867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OmpA family protein"
                     /protein_id="HDF3911389.1"
                     /translation="MLYDEDEKEENNERWLLTYSDLITLLMIFFVIMYSMSNVDAEKY
                     KQLSQSLNSAFGGSSGVIEGGNSKIEPVVEPGSNDLDTLQNAKFKKVGEEIQKYLNEN
                     GMANSVSLRVQDRGLVISLKDTILFDTGKAIVKDNSRDKIIQIGKMLNEMNSYMRVEG
                     HTDNMSIKNSEFKSNWDLSVMRATNVVQLLIDNAGIAPDKLSAVGYGEFRPIAENSSE
                     EGRSKNRRVDIVLVDSKYDNVENVSKDK"
     gene            complement(11916..12704)
                     /locus_tag="PC494_000868"
     CDS             complement(11916..12704)
                     /locus_tag="PC494_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor protein"
                     /protein_id="HDF3911390.1"
                     /translation="MTTLIFFIVGIASLVVAFVIDGGHVGALFVFSSALVVFGGTIGA
                     VGASTPFPVFKKSIKIMLLAFKNKKPNNIENIIYFKEIATKARKEGLLSIDKEISEND
                     ELDPFIRKGLELMVDGVDAVTIRNILESQIQITSKRHKEGIAIFDSAGGYAPTLGIIG
                     TVMGLVHILGNLSSNPDALGPQISVAFLATLYGVGSANLIWLPIASKLKAINQQEISE
                     RLLVIEAILSILEGDNSNLMTEKLKIFLNSKELIELEEIGGRAE"
     gene            complement(12792..12882)
                     /locus_tag="PC494_000869"
     tRNA            complement(12792..12882)
                     /locus_tag="PC494_000869"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(12846..12848),aa:Ser,seq:gct)
     gene            13141..13905
                     /locus_tag="PC494_000870"
     CDS             13141..13905
                     /locus_tag="PC494_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HDF3911391.1"
                     /translation="MLPQERYEKILSILKSDNIIKINDIVQMFDISIETARRDLAHME
                     SIGLLKRVYGGAIPVIASSVELNYVKRKKINSNDKKQIAIKCSEFINTNDTIFMDTGT
                     TVLEVSKNLKDKKNLTVITNSILVANELMNTNIKVYVLGGYLRETEGSFSGPLTLSAI
                     EQFNVDKAILGAGGITLENGISDYHLEEALVRKKMIERSRKSIVVVEPPKFGINSFAS
                     VAPIEHIDTIITSASIDHNIIIEFSQKGIPLVIADN"
     gene            complement(14186..15301)
                     /locus_tag="PC494_000871"
     CDS             complement(14186..15301)
                     /locus_tag="PC494_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization protein EutH"
                     /protein_id="HDF3911392.1"
                     /translation="MPFDKIILYIMAVGVLLGALDRIIGNKFGLGEQFEEGFNSMGPL
                     ALGMVGIVCLAPVISDVLGPIIIPIFNLCGADPSMFATILANDMGGYPLAMELAHNKE
                     AGMLAGLVVSSMLGCTLVFSIPVGLGLIEYEDRPFFAKGLLIGLITIPFGGIIGGLIA
                     GFNLSMVIINMIPVIILAVILAVGLKFNSTLMINGSLIFGKFISILITIGLGAAAFQE
                     ITGIVLIKGMTPIREGIQVIGSIAIVLLGTFPILHLLVKVLNKPLTIVGGKLGMDATS
                     AAGLVFTLANSIPVYKMMKDMSPKGKVVNTAWLVCATAALGDHLGFTAGVVPEMITPV
                     VIGKLVGGVLAIALAILMTKDLTLEEEQSIKMKKDAV"
     gene            complement(15342..16868)
                     /gene="glpK"
                     /locus_tag="PC494_000872"
     CDS             complement(15342..16868)
                     /gene="glpK"
                     /locus_tag="PC494_000872"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HDF3911393.1"
                     /translation="MKYVLAIDQGTTGTRAVLINEKSEFVFSDYMEHTQIYPQSGYVE
                     HDPIEIWNNTKTVSNNVLQQAFENGINESDIKGIGIDNQGETVMLWDKNTGKPLYNAI
                     VWQCRRTYDYVENLKNIPGLENKIIDKTGLIIDPYFSGTKIKWVIDNVKGVKEKIKNG
                     EVLAGTLDSWLIWKMTGGKSFLTDVSTAARTMLFNIRDMDWDRELLDIIGIPRSILAD
                     IMPTSGDFGTTDKEAFCGVSIKITASMVDQPAALFGNGCFEPGMVKNTYGTGCFLYMN
                     IGEELNIAGNGILTTVAWKIGDKVTYAYDGGVYIAGAAIQWLRDGIGVIKNYSETDDM
                     ANSISSTGGVYFVPAFAGIAAPYWDQYARGTMVGITGSTKKEHIVRATLESVALQVKD
                     VVDSMNLASGKKIKMLRVDGGITKNNFTMQFQSDILGIPIEIAENPETTVLGVGYMAG
                     LSCGVWNSIDEIRSEFTISKKYIPNMTNQKREEILLGWNQAVKRAMNWENDTKKVCAN
                     "
     gene            17161..18258
                     /locus_tag="PC494_000873"
     CDS             17161..18258
                     /locus_tag="PC494_000873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--glyoxylate aminotransferase family
                     protein"
                     /protein_id="HDF3911394.1"
                     /translation="MKKTYLFSPGPVMVTDKVRNSLLHYDICHRGNEFMNLFKDTQQK
                     INKLYNATSNYYSLIVSGSGTSVNECVLSSIFDKEDAVLLVSNGVFGERLEEILSTYN
                     VKTYKPNFEWAEYPDLDILEKYIIENSDIKVIAMVFHETSSGMINPVPELGKLAKKYN
                     KIFFVDAISASAGEYIDVEEFNIDIITGVGGKALGAFPGSAYLCAKESILQNIKENQC
                     KNVYLNLYKHYKVAKSSSQTPNTPNVTLIFALNEALTEFLEDDSKIERYKECSAILRN
                     GMEELGLTFLLPDKYMSNTVTSVFLPKEINVNEFILGLERESGYVVYPGKGKFLDANI
                     FQVANMGEIYPDDCYKFLDILKSKLEIKKVI"
     gene            complement(18749..19261)
                     /locus_tag="PC494_000874"
     CDS             complement(18749..19261)
                     /locus_tag="PC494_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3911395.1"
                     /translation="MKVKKFKSGIVMALTVMAIGASLTNVSAMELNKSKEFETKYNEM
                     KRDFQEEYGKEDKFNITLDDEFTKEEVNGAKGIIKTTNKMNNEVVVLNYFDEMKSGIE
                     FELKPKAEKNAILRDEFQQGYGKEDKFKVVLDDEFTKEEVNGAKGIIKTTDKETGEVI
                     VYNYFDELEK"
     gene            19814..20695
                     /locus_tag="PC494_000875"
     CDS             19814..20695
                     /locus_tag="PC494_000875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4300 family protein"
                     /protein_id="HDF3911396.1"
                     /translation="MKKRLIIMILSVVLVLSSILTIFAYSNIKYNNNKLIYSNMIDKK
                     TQNSVKEILKENKINEKDIDTFIKAVNNYNKLQVKILQNNINISKSGYSSINAKQVPY
                     NLEKLQDNWVKKFPDYMDVNCRITAFRLFKDFINSNKKFTGDSIDLNVDLDTIMNNKD
                     AKFSTKDVEKFINFFSAIPAKDTDDTIKIAEQIKNEWKKRKISFKNNKNISIINGFLR
                     YPETKNVFIGHTGICIKTKNGILFLEKYGVTSPYQVTKFKNKEDVKNYMFNRLKMSEG
                     EIELPDPIIMENDKLMK"
     gene            complement(21008..21787)
                     /gene="hisJ"
                     /locus_tag="PC494_000876"
     CDS             complement(21008..21787)
                     /gene="hisJ"
                     /locus_tag="PC494_000876"
                     /EC_number="3.1.3.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphatase HisJ"
                     /protein_id="HDF3911397.1"
                     /translation="MKDGHIHSPYCPHGSKDDFEKYVQRAMDVGITEMTFTEHFPYAN
                     GFRDPAPENDSCMSIEDLPKYFNDVKKLKEKYEGKIKINVGSEVDFIEGYEEGIKANL
                     NKYGEELEDSLLSVHIIKIDDDYYCVDYSVEEFQNLIDKLGSIEAVYNKYYETLIKAV
                     NSDLGIHKPKRIGHLNLVRKFNQVFPYDYKGNTILEELIKLIKEKGYELDYNVSGNRK
                     EYCKEPYIDGYLLELVKKYDIPLVLGSDSHCAEEINKYDII"
     gene            complement(22333..22683)
                     /locus_tag="PC494_000877"
     CDS             complement(22333..22683)
                     /locus_tag="PC494_000877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc transporter"
                     /protein_id="HDF3911398.1"
                     /translation="MIFDKEIVRYHHGHHDHDHCHEHTHGDICHEHPHDHAHDHDHEH
                     SHEESSESKDEKTLKILLVHWINHNETHEEGFREWVEKARAIGKEETAKSIEKAIEYM
                     EEANKMLLEAKKHM"
     gene            complement(22699..23115)
                     /locus_tag="PC494_000878"
     CDS             complement(22699..23115)
                     /locus_tag="PC494_000878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3842 family protein"
                     /protein_id="HDF3911399.1"
                     /translation="MIIAVIDGMGGGIGAQIVSSLREELPTYVEIYALGTNSIATSSM
                     MKAHANKGATGENAIVVSAKKANIIVAPISVIIPNSMMGEVTCNISEAIADSEALKIL
                     LPIMPENVELVGLEGKPLALLVKDSVNLIKKEFNIK"
     gene            complement(23134..23325)
                     /locus_tag="PC494_000879"
     CDS             complement(23134..23325)
                     /locus_tag="PC494_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CooT family nickel-binding protein"
                     /protein_id="HDF3911400.1"
                     /translation="MCESSAFICKSNNELEKVMENVVNIDPCDGKIYLTDLLGEQKII
                     DGIIKEIRLMDHKIIIQEN"
     gene            complement(23476..24291)
                     /locus_tag="PC494_000880"
     CDS             complement(23476..24291)
                     /locus_tag="PC494_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase family protein"
                     /protein_id="HDF3911401.1"
                     /translation="MNQWRVIHNKSYEGAMNMAIDEAIFTAYKKGHNKPTLRFYTWEP
                     ACLSIGYFQKLEDEIDLDKCRCMNIDYTRRITGGRAVLHDNELTYSIIIGEDNPLIDK
                     SINLSYRYISEGLVKGLNLSGIETDNLNRGERISRENLSAACFNAHASYEVTINNKKV
                     IGSAQSRKDGVLLQHGSIILDFDVEKLFKLIKTKTPELKERAMKFTAKKASGIENEIG
                     RKIDIDILQKNIVKGLAEQFNVEFVEGDLTDYEKQLVKELYEKYKNEEYNKKR"
     gene            complement(24338..25276)
                     /locus_tag="PC494_000881"
     CDS             complement(24338..25276)
                     /locus_tag="PC494_000881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HDF3911402.1"
                     /translation="MIRLSVGTAIELGILNKKSDIPPTTAYIMIGEKCINKCSFCSQS
                     IESSTRKDKLSRVIWPEFSKEEILDALKAYKGKNIKRICIQSMASEEAHNSVLDFINY
                     ISGKIDMPISLSAKLENDEQIKKFFSAGVNKIGIAIDAANKELYEKIKGNNYDEKLKF
                     ITEMSKSYPNKISTHIIVGMGESHEDIYNLYTYLKENDVTISLFAFTPVRGTKMEKIS
                     QPSIESYRRVQLMSYMINKGYPKEYFKFKNGYLNSIKLDNDILKDINKGYPFEIRGCK
                     DCNRPYYNERPGSTIYNYSRPLNQSEIDLAIREINL"
     gene            complement(25273..26145)
                     /locus_tag="PC494_000882"
     CDS             complement(25273..26145)
                     /locus_tag="PC494_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HDF3911403.1"
                     /translation="MNKNLSEKMKIAFDIKLKNFGNKIEFAYPNQTLALSTTSNQCSL
                     KCAHCNGHYLNNMVPIEEYEEKVQSRNITSFLLSGGCSYEGDVPINTHINTIKNLKEQ
                     GYRLNAHLGLMDKDSIVELCKYLDIVSFDLVFDDETIREVYKMKKSKEDYIEVYNTIQ
                     EHTEVAPHICIGLKGGQIKGEYEIIEYLQKNPPNKLTFIVLIPTKGTEYENVEPPELE
                     GVADILCEARINLPDTEINLGCMRPRGVYRKELDQLSIMCGVNRIVLPSRSAKNKAIE
                     MNMTINECKECCVL"
     gene            complement(26170..28098)
                     /locus_tag="PC494_000883"
     CDS             complement(26170..28098)
                     /locus_tag="PC494_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4445 domain-containing protein"
                     /protein_id="HDF3911404.1"
                     /translation="MIKVSFTPNNKEVYCNEGDILLEVARNADIFIDAPCNGNVSCGK
                     CKVKLLNGKVDTEKTRHITDDEWEQGYILACCTKVISDIEIEVPSKVSSSMHGMKIEG
                     SNKKEDREIFERAKKIIEEHNLQFKTNIKKKYIEMEEPNLDDNISDVDRLERYVRNNL
                     GYNEIDFRLDILRKMPTVFRKSDFKVTITYVQKQKKLTIINIEQGNKENSLYGVAIDI
                     GTTSVVVCLVDLYSKEVVDKASSGNAQIKYGADVINRIIYSTKKNGLETLHKAIVEET
                     INPLLKTIYERNGIDKEDVVTLVAAGNTTMTSLFLGVYTDFLRQEPYIPPFLKSPKLM
                     GENVGLFVNDSAYVYLAPSVASYVGGDITAGVLSAGIWSSEENVLFIDLGTNGEIVFG
                     NKDYMMSCACSAGPAFEGGGISCGMRASAGAIEKVIIDKDTLEPTLKIIDECAPVGIC
                     GSGIIDLICQMITKGVIDRRGKIYRDLDNKRVRFNEHEIGEYVLAFKEEFDLENDIVV
                     NEVDIDNFIRAKGAIYSGAYTLVDSLGMDFSILDRVYIAGGIGNNLDIENSIIIGLLP
                     DIDREKFTYIGNSSLVGSYLALISKDAKNKLEEIGNQITYVELSVYPSYMDEFISACF
                     LPHTNIEQFPTAKKLLEE"
     gene            complement(28210..28587)
                     /gene="gcvH"
                     /locus_tag="PC494_000884"
     CDS             complement(28210..28587)
                     /gene="gcvH"
                     /locus_tag="PC494_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system protein GcvH"
                     /protein_id="HDF3911405.1"
                     /translation="MKLLPELKYSKDHEWVKVIDGDVVYIGITDYAQDQLGEILFVET
                     PEVEDTVTKGVDFGVVESSKVASDLISPVNGEVLEVNEKLEDEPECINEDPYENWILK
                     VKLADVAELDTLLSDKEYEAGLE"
     gene            complement(28674..30800)
                     /gene="cdhC"
                     /locus_tag="PC494_000885"
     CDS             complement(28674..30800)
                     /gene="cdhC"
                     /locus_tag="PC494_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CO dehydrogenase/CO-methylating acetyl-CoA
                     synthase complex subunit beta"
                     /protein_id="HDF3911406.1"
                     /translation="MNLYNIIFTGSEQALGAAQAMLAEAIEKNGKEHKVAFPDTAYSL
                     PCIYAATGQKMNTLGDLEGALEVVKSLINRTHLLEHAFNAGLATALAAEVIEALKYST
                     MDAPYSEPCAGHITDPIIRSLGVPLVTGDIPGVAVVLGECPDAESAAKVIKDYQSKGL
                     LTFLVGKVIDQAIEAGVKMGLELRVIPLGYDVTSVIHVVSVAVRAALIFGGLTPGDLN
                     GLLEYTANRVPAFVNAFGPLSELVVSAGAGAIALGFPVITDQTVLEVPMNLLTQKDYD
                     KIVATSLEARGIKIKVTEIPIPVSFAAAFEGERIRKSDMFAEFGGNRTEAWELVVKKE
                     ATEVEDHKIEIIGPNIDEVDADGVLRLPLAVIVKIAGKNMQEDFEPVLERRFHYFLNY
                     IEGVMHVGQRDMAWVRISKDAFDKGFRLEHIGEVLYAKMLDEFESVVDKCEITIITDA
                     EKVSELKGEAIAKYNARDERLASLVDESVDTFYSCNLCQSFAPAHVCVVTPERLGLCG
                     AVSWLDAKATKELDPTGPCQPIEKGECLDDRTGVWNSVNETVNQISQGAVESVTLYSI
                     LEDPMTSCGCFECICGIMPEANGFVVVNREFASVTPVGMTFGELASMTGGGVQTPGFM
                     GHGRHFISSKKFAYAEGGPERIVWMPKELKDYVADKLNATVKEMTGIENFCDMVCDET
                     IADDSEGVLAFLEEKGHPALAMESVM"
     gene            complement(30857..31663)
                     /locus_tag="PC494_000886"
     CDS             complement(30857..31663)
                     /locus_tag="PC494_000886"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HDF3911407.1"
                     /translation="MEKFMIIGERIHCISPSIRKALAERDPAPILKRAKEQLEAGAHY
                     IDFNIGPAERDGEEIMTWGIKLLQSEFNNVPIALDTANKKAIEAGLKVYDRTNAKPII
                     NSADAGSRFDLIDIAAEYEAMVIGLCAKEGIPRDNDERMAYCQEILEKGLMLGMEPTD
                     ILFDPLCLVIKGMQEKQVEVLEAIKMMTEMGLLTTGGLSNVSNGCPKHVRPVLDSAFL
                     AMAMANGFSSAIMNPCDPELMKTVKSCDIINGASLYADSFLELNEGGFAF"
     gene            complement(31713..33080)
                     /locus_tag="PC494_000887"
     CDS             complement(31713..33080)
                     /locus_tag="PC494_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA decarbonylase/synthase complex
                     subunit gamma"
                     /protein_id="HDF3911408.1"
                     /translation="MALKALDIFKLTPKKNCKDCGFPTCMAFSMKVASGAVEVGKCPH
                     MSDDAIAKLSEATAPLMKALKVGAGASEYELGGETVLFRHEKTLVSRNRYAVSFCTCM
                     SDEAVDAKIANMKKVDYVRIGEQMKVEMAVLEYCGDKDAYLKLIDKIKGSGLEVAYIL
                     ACDDAQVVKEAVEVLKDARPMVYGATKENYKDMIEVVKGASLPLGVKAGSLEELYETV
                     ELIQAAGYKELVLDVTGENIKDTYTNAIQVRRTALKEQDRTFGYPSIVFANRLSNSNP
                     MMEVALSSIFTIKYGSIIVIDDISYAKALPLFALRQNIYTDPQRPMRVEPKIYPINNP
                     DENSPVLVTVDFALTYFIVAGDIERSKVPVWLVIPDAGGYSVLTSWAAGKFGGNSISA
                     FIKESKVEEVTNCKDLIIPGKVAVLKGDIEDNLPGWNVVIGPEESMELPKFLKGYQEK
                     ACQTN"
     gene            complement(33111..34055)
                     /locus_tag="PC494_000888"
     CDS             complement(33111..34055)
                     /locus_tag="PC494_000888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA decarbonylase/synthase complex
                     subunit delta"
                     /protein_id="HDF3911409.1"
                     /translation="MAFKMSTQKYSGKISEVEVGIGEKAIKLGGENVLPFYSFDGEVG
                     NSPKIGIQISDVYPESWTDSYKELYKDVANCPVEWAKYVEANTQADFICLKFDGSDPN
                     GLDKSVDECADVAKAVIEAIKLPLVVAGSGNHEKDGKLFEKLAQTLDGHNCLFMSAVE
                     DNYKGVGASAGMAYAHKVGAESSVDINLAKQLNVLLTQLGVKGENIVMNVGCSAVGYG
                     YEYVASTMDRIRLAAFGQNDKTLQMPIITPVAFEVGHVKEAIAPIEDEPDWGCPEERT
                     IAMEVSTAASVLVGGSNAVILRHPKSIETIKELVNALA"
     gene            complement(34075..34845)
                     /locus_tag="PC494_000889"
     CDS             complement(34075..34845)
                     /locus_tag="PC494_000889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HDF3911410.1"
                     /translation="MGYNIAVAGKGGTGKTSLTGLLIDYLVKDKKGPVLVVDADANAN
                     INEVLGIEVEATIGEIREEVNQREKLGNAFPGGMTKAQYLQFRLNSIIEEGEGYDLLV
                     MGRSEGEGCYCFVNGILREQVNKISGHYKYLVMDNEAGMEHLSRKVTRHVDTLLLVSD
                     CSRRSIQAVARIRDLAEELKLSVGRILLIVNKVPNGVMNDGVKEEIEKHNLELIGVVP
                     MDELIYEYDSTGIPLVNLPEDSKSKVAMKEIFAKLELK"
     gene            complement(34901..36286)
                     /gene="lpdA"
                     /locus_tag="PC494_000890"
     CDS             complement(34901..36286)
                     /gene="lpdA"
                     /locus_tag="PC494_000890"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HDF3911411.1"
                     /translation="MKIVVVGGGPGGYVAAIKASMLGADVTVVEKRRVGGTCLNAGCI
                     PTKALLASSGVLNTVKEAKDFGIEIDGTVKPNFTAIMERKNKVVNQLISGIEFLFEKR
                     GVNLVNGFGKLIDKNTIEVTKDDGTVETIKADKIILANGSVPVVPRMFPYDGKVVITS
                     DEVLGLEEIPESMLIVGGGVIGCEIGQFFRALGTEVTIVEMVDQILLNEDKDVAKQLL
                     RQFKKDKIKVITGIGVQTCEVVDGKAVATLSNGKVIEAQYALVCVGRRPNLDNSGVED
                     IGIEMERGKVVVNEHLETNVEGIYAIGDIIDTPFLAHVASKEGIVAVENALGKTKVVD
                     YRAIPRCVYTEPEVAGVGKTEKQLEAEGVEYNVGQFDFRGLGKAQAIGHFQGFVKVIA
                     DKETDKIIGAAVVGPHATDLLTELSLAVHLGLTVEQVGDAIHPHPSLSEGLMEALHDV
                     HGECVHSVPKL"
     gene            complement(36330..37211)
                     /locus_tag="PC494_000891"
     CDS             complement(36330..37211)
                     /locus_tag="PC494_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate reductase"
                     /protein_id="HDF3911412.1"
                     /translation="MSLLRETLESGKFAVTTEMAPPKGTDLSHLIECAKPLVGRVHAA
                     NVTDFQSAVMRATSLATCKLLKDAGLEPVIQITGRDRNRIAIQGEMLSAGVFGINNLL
                     ALTGDHTSVGDHPQAKGVFDLDSVGILQTAETLMAGTDMAGNKLKGSPDFYLGASVTP
                     EYSPIEVQLLKMKKKIKAGAKFFQTQALYDINTMRKFRELTRDMDCKVLAGIVPLKSP
                     GMAKFMTANVPGIFVPDEQIERLRAAGKENWVSEGIKMAGELIKQLKEEDLCDGVHIM
                     AIGAEENIPAILDAAGL"
     gene            complement(37247..37921)
                     /locus_tag="PC494_000892"
     CDS             complement(37247..37921)
                     /locus_tag="PC494_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate reductase C-terminal
                     domain-containing protein"
                     /protein_id="HDF3911413.1"
                     /translation="MIISENKPLEEVLGYLKDFDKLVLVGCNQCAATCKSGGEEEVLK
                     MKETLEGEGKKILGYVMLDPACNLLKSKKDLKALKEETKEADAVLSLACGDGTQTIVK
                     NLKDKPVYPANNTLFIGEVQRVGEYEEACKACGDCELGWTGGICPVTMCAKGLMNGAC
                     GGAKNGKCEVNSENDCAWIKIYERLEAIGQLDNLAEIRPPKDYSKQNNPRSLSAKKKK
                     EAAANS"
     gene            complement(37956..38828)
                     /locus_tag="PC494_000893"
     CDS             complement(37956..38828)
                     /locus_tag="PC494_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 5,10-methylene-tetrahydrofolate
                     dehydrogenase/5,10-methylene-tetrahydrofolate
                     cyclohydrolase"
                     /protein_id="HDF3911414.1"
                     /translation="MEGMSTKGQIIKGKPVADKISEELIKEVDLLVKEGINPKLTIVR
                     VGARSDDLSYERGALKRCQNIGITTEVLELAEDITQEEYIDVLKRVNDDKNVNGILCF
                     RPLPKHLNEEVIKYVIAPEKDVDCFSPINSAKVMEGDKSGFPPCTPTAVVEILKHYNV
                     DLKGSKVTVLGRSMVVGKPVSMLLLSEHATVTICHSKTKNLSGVAAEADVLIAAIGRA
                     KMVDESFVKDGAVVIDVGINVDEEGNLCGDVDTNAVLDKVSMITPVPAGVGSVTTSIL
                     AKHVVKACKLQNNK"
     gene            complement(38920..39552)
                     /locus_tag="PC494_000894"
     CDS             complement(38920..39552)
                     /locus_tag="PC494_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclodeaminase/cyclohydrolase family protein"
                     /protein_id="HDF3911415.1"
                     /translation="MKIADKTCVDFVEVLSSKEAVPGGGGAAALVGAIGMALGSMVCN
                     LTIGKKKYAEYEESVKEILSKAGKLEKDLLKMIDDDAECFLPLSKAYGLPKETEEEKR
                     IKAETMEKALKVACEVPLNIVRVCYEAIKLHEDLVDKGSRLAISDVGVGVQCLRAAIL
                     GGQLNVVININSIQDKEYVNKVKTEVDKLVEDGVKICDEVYAKVEKALGK"
     gene            complement(39657..41333)
                     /locus_tag="PC494_000895"
     CDS             complement(39657..41333)
                     /locus_tag="PC494_000895"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014355320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HDF3911416.1"
                     /translation="MGFKSDIEIAQEAKPQDIREVAKKLGLGEDDVELYGKYKAKVDY
                     NLLKRETGKKAKLILTTAINPTPAGEGKTTTTIGVADAFAKLDKNVLVALREPSLGPV
                     FGVKGGAAGGGYAQVVPMEDINLHFTGDFHAIGAANNLLAAMLDNHIHQGNALRIDPK
                     KITWRRCVDMNDRQLRNIVDGMGKKGDGAVRQDGFDITVASEIMAAFCLASDISDLKE
                     RLGNIIVGYSYEGEPVTARQLKANGAMAALLKDALKPNLVQTLEGTPSFVHGGPFANI
                     AHGCNSVIATRMAMHFADYVITEAGFGADLGAEKFLDIKCRMANLKPDAVIIVATVRA
                     LKYNGGVAKADLNNENLEALEKGLPNLLKHVENITQVYGLPAVVAINRFPLDTEAELK
                     LVEDKCKELGVNVALSEVWAKGGEGGIAVAKEVLRLLDEEENNFRFCYEDDLSIKDKI
                     NAIATKIYGADGVDYTPEADKEIANLEKLGFTKVPVCMAKTQYSLTDDQTKLGRPTGF
                     RITVRQATISAGAGFIVALTGEIMKMPGLPKVPAAEKIDVDENGVIAGLF"
     gene            complement(41582..42361)
                     /locus_tag="PC494_000896"
     CDS             complement(41582..42361)
                     /locus_tag="PC494_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HDF3911417.1"
                     /translation="MKIAITGKGGVGKTTFSSMLSRMFAEDGYRVVAVDADPDANLAL
                     ALGFPKEVYESIVPISEMKKLVSDRTAASVGSFGKMFKMNPKVDDIPENFCKEYNGVR
                     LLTLGTVDSGGTGCVCPEHVLLKRLCSHLILQNKDVVVMDMEAGIEHLGRGTAQGVDA
                     FIVVVEPGERSLQTYRKVKKLGHDIGVNKVFVVGNKIRNKEDEEFIIQNLEDGESLGF
                     IYYNQDVIDSDRANQSPYDSSETTKEQIKAIKDKLMSLKDK"
     gene            complement(42671..44590)
                     /gene="cooS"
                     /locus_tag="PC494_000897"
     CDS             complement(42671..44590)
                     /gene="cooS"
                     /locus_tag="PC494_000897"
                     /EC_number="1.2.7.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic carbon-monoxide dehydrogenase
                     catalytic subunit"
                     /protein_id="HDF3911418.1"
                     /translation="MDEKMLTIDLNSQKMIAKAREEGVETMYDRKEGFKAQCGFGLQG
                     VCCRICGMGPCRISPKTPRGLCGADEHTIVGRNFARMVAGGTAAHSDHARDIAHTLAL
                     ADPNGNYKIRDEAKLITLAKEWDVETEGRDIYDVAHEVAEIALMEFGKPFGTLRFIKN
                     APEPRQKIWKEYAIEPRAIDREIATIMHSTHIGCTGDIDSLIHMSLRTSMADGWGGSM
                     IGTRLSDILFGTPVPRRTEANLAVLEENKVNIILHGHEPALSEMIVLASEEPDLVALA
                     KEVGADGINLAGMCCTGNEITMRHGVKIAGDFHQQELAIITGAVEAVIVDVQCIFPAL
                     ARVADCYHTKFVTTSPKAKITGSTYIEFREEQALDDAKAIVKEAILNFKNRDKSKVLI
                     PELKSGATVGYSVEAVVNQLDRVVNSHIDPAGTVKPLTDCLKAGVLRGAAGVVGCNNA
                     KGVSNEAHVTIMKELIKNDIIVVTTGCGASAAAKFGLMESDAAEKYAGKGLATVCKLV
                     GIPPVLHMGSCVDISRILDLVGAAANYLDMDMCDLPVVGIAPEWMSEKAVAIGCYVVA
                     SGIDTYLGIMPPIAGSSRAVDILTSELKDKVGATFTVNTNPKELAATIIEDIEKKRVH
                     FEALVEEKMTEKAEA"
     gene            complement(45197..46108)
                     /locus_tag="PC494_000898"
     CDS             complement(45197..46108)
                     /locus_tag="PC494_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional enoyl-CoA hydratase/phosphate
                     acetyltransferase"
                     /protein_id="HDF3911419.1"
                     /translation="MIKKLDDILEQLKGGEKIVLSVAAAHDKEVLMAIKDAVERNIIT
                     PILVGNEGKIREISKEIGFDLSGIKIVDKDDIKECAEIAVKLVSSKEADFVMKGLLDT
                     SVILKEVLNKDYGLRTDSLLSHVMVYELEKYHKLLITTDGGMNIAPDYEQKAKILKNS
                     IKAAKALGMETVKVACLAAKEKVNPKMQATVDADMLAKACKEGEFGENVIVEGPLAFD
                     LAVSKEASEIKGFKSEVSGDVDIILVPTIEVGNGIGKAFTYMADSKSAGIIMGAKAPI
                     VLVSRADSHESKLYSIAYGAIVAKNMK"
     gene            complement(46224..46802)
                     /locus_tag="PC494_000899"
     CDS             complement(46224..46802)
                     /locus_tag="PC494_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HDF3911420.1"
                     /translation="MNINEFLTHINQRKPVSSKSEIHEFMVKLSNEAMKITSKLNSSY
                     HEPEEVRSLFSELIGKKVDESFFMFPPFYTDCGKNITIGKNVFINSSCHFQDQGGIDI
                     GDNTQIGHNVVLATLNHGIAPEKRGTTYPSPITIGKNVWIGANVTIVPGVTIGDNVII
                     AAGAVVTKNVAENTIVGGVPAKLLRVIDEIPE"
     gene            47028..47951
                     /locus_tag="PC494_000900"
     CDS             47028..47951
                     /locus_tag="PC494_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDF3911421.1"
                     /translation="MEIRVLRYFLAIAREESISGAATFLHITQPTLSRQIMELEEELG
                     VKLLVRGNRKITLTNEGRLLHKRAEEIISLVDKVELEFDNPNEIISGDIYIGSGETEA
                     MRLIARTAHHFHQKYPNVRYHLFSGNADDVTEKLDKGLLDFGILIEPANIQKYDYAQI
                     PATDVWGLLMRKDSALASQSTINPKDLCNIPLIISRQTLVDKAISKWLQDSNEKLNII
                     ATYNLVYNASLLVEEGLGYALCLDRLVNTTENSNLCFRPLSPPLEAKLNIIWKKHQIF
                     SKAAEKFLLQIQKDFSSIMLDTSKLDTPKEK"
     gene            complement(48123..49265)
                     /locus_tag="PC494_000901"
     CDS             complement(48123..49265)
                     /locus_tag="PC494_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HDF3911422.1"
                     /translation="MDFKIEKYLLKKTEELAFITIKHGGEFKLKSYEVPKGGLDVPIK
                     NEVLVKGIKEKTAQDKLNSMSIADAMIYIIGIDSKFKNNAEYEKFLNALSKDIDLDLK
                     SYMGYMSRKYFEIGEHTDSLIYIKAFITMYPDDLDAMYNYAIVCQEIAKQYQKDMDDK
                     AMNAFLLEAMAKLEKVIDVDENFALGYYHLGYHYYNQGQYLKTKLTWEEALRLGLDAD
                     LVAEVQENLGKMDFKVQYEEGYTLVFQGKFKEGLEKLLPLEEEHMDWWNLLFMIALGY
                     KGMGEIEQAKMYLEKILIIKPNQVDTIVELGLCEAYKNNLDKAIEYFEQAAKIKEDPE
                     ILCNLGMAYLNNGDIDDATYYIERAYELNPQDEITIACLRELGINK"
     gene            complement(49283..51037)
                     /locus_tag="PC494_000902"
     CDS             complement(49283..51037)
                     /locus_tag="PC494_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="B12-binding domain-containing radical SAM
                     protein"
                     /protein_id="HDF3911423.1"
                     /translation="MKILLTTLNSKFIHTNLAIRYLKEFVRDLIEVNMKEYTINNDLD
                     YILKDIYKNEYDIILFSTYIWNVGDIVKLCDNLKKIRPNTKIALGGPEVSYDSYEAMK
                     KYDFVDYILYGEGELIFRDLVLHLQGKMEINDVNGLVYRQGNEIIVNKPMELLQNLDE
                     IPSPYENLNPKEYENRIVYYESSRGCPFNCQYCLSSTIPGLRYFSLDRIKSDLKALID
                     ARVSQIKFIDRTFNANRKVAMEIMDFLMKNDNGYTTYHFEVTAYLIDDKMLEFLADCK
                     EGLFQFEIGVQSTNEKTLDAVGRRDDFKKLSHVVQTVASYRNIHQHLDLIAGLPYEDY
                     KSFENSFNDVFNLGIEHLQLGFLKMIKGTGMRKVADEHGFKYKDYAPYEFLYNNYISY
                     EETLKLKDIEDILERYYNSKNFVLSMRYIIGRFYKKSPFKFFEVFAKYFDENGYFDLA
                     QGKNQLYKILMDFYNEKINIDNDVFNDILKYDYISLGKTSNIPQFFNKLDVDDFKNRC
                     HVFLQDNDNLSTYLPSFVDKPAKHIIKYVHFEPFRFNVVDLKNDINTEIREVENVVLF
                     EYDDKKIFEKSKTHKVEI"
     gene            51173..51379
                     /locus_tag="PC494_000903"
     CDS             51173..51379
                     /locus_tag="PC494_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3911424.1"
                     /translation="MELIEKVSINSLSKRDLLLIIKSLEYTNENTQISDFIDLRNNIV
                     KELCFLTDTKEKDFLDYLEKNSTL"
     gene            complement(51384..52307)
                     /locus_tag="PC494_000904"
     CDS             complement(51384..52307)
                     /locus_tag="PC494_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3911425.1"
                     /translation="MNDELLKKVYTSSFSSASRALKDLTIINTKSLIDDKTQRCVYID
                     ENRLRDELIYYRFYGEKIGNINFLNILLPLILSNTNIQKSEDEVIKLIKKYVIYFKKE
                     ELLFDYLLGSVVYNSIMHNLINNSKIEYVELLQSIKDKIIGFSIELDKSDVVKFQMAR
                     IKAIQLIDKYIDLKSEDYDEESILLNVLNVLYDVYMEDRIVENEGINSIKKSILSILG
                     EDSKLNEDNIDFIFSMSEYVVKLRKYKIGVKAYNKSIDPRSLIRLEEGNTIIDPIFNQ
                     ITVMSKTFNDNILSIKINSKSGIYILKFKKV"
     gene            complement(52562..54262)
                     /locus_tag="PC494_000905"
     CDS             complement(52562..54262)
                     /locus_tag="PC494_000905"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HDF3911426.1"
                     /translation="MQDFKVAISNCLKEKIEDLSKEEIEALIEVPPNKDMGDYAFPCF
                     KLAKVFRKAPNMIASELAESIEPSGEITKVIQLGGYVNFFVNKSQLAETVIKKVLDEK
                     ENYGHSDFGKDKTVIVEYSSPNIAKPFHIGHIRTTVIGNALYKIYDSQGYKTIRINHL
                     GDYGTQFGKLIVAFKKWGEKEVVESNPIPELLKLYVRFHDEAEQHPEMEDEARAWFNK
                     LENGDEEAQELWQWFRNESLKEFNRVYKLLDIEFDSLAGESFYSDKMNRVIELLEEKN
                     LLKESKGARIVDLEEYKMPPALITKNDGSTLYMTRDLAAAIYRKETYDFDKCIYVVGS
                     QQNLHFQQWFKVIELMGYDWAKDLIHVGFGMVALEEGTMSTRKGRVVFLEDALNQAID
                     KTKEIILAKNPNAKNVDEISKQVGVGAVVFQELSNSRIKDYTFSWERTLSFDGETGPY
                     VQYTHARCCAVLRKAEVEVTSDIDYSLLADEDSAEVLRVIESFNKNILLALKKNEPHI
                     VTRFMLDLAQAFNKFYHDNPILVENLEIRKARLALVLATKQTLENSLKLLGMHAPERM
                     "
     gene            complement(54725..55138)
                     /locus_tag="PC494_000906"
     CDS             complement(54725..55138)
                     /locus_tag="PC494_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF523 domain-containing protein"
                     /protein_id="HDF3911427.1"
                     /translation="MILVSACLIGINCKYSGDNNDNEKVKEYLKGKEFTLVCPEQLGG
                     LSTPRPPAEIVDGKVITKDNKDVTENFVRGANETLKIANLYVCSEAILKEGSPSCGCN
                     LIYDGSFSGKKIPGKGITARLLEEEGIKVKSEKDL"
     gene            complement(55204..57582)
                     /locus_tag="PC494_000907"
     CDS             complement(55204..57582)
                     /locus_tag="PC494_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HDF3911428.1"
                     /translation="MNEKSLRVLEYNKIIDLLKKKASSSLGLKYIENLVPNTDFVEVK
                     SMLEETSEAQSIIIKRGSVGLEGIHDIEDKVKRAYIGASLDPGSLIMIADTLRVARRL
                     RNSLSSSDEEDFNYPIIQSLSNSLYVYKDIEDQIYNAIISEVEISDNASSTLRDIRRR
                     IAQKNQSIRSKLNSIISSTTYQKYLQDAIISLRGDRFVVPVKSEYRSQVAGIVHDQSS
                     SGATLFIEPMTIVEMNNELRQLKLGEQEEIERILSELSAMVGEVSEDLISNQEILGRL
                     DFAFSKGKLSIQMRGIEPTLNEDKYLNIKNGRHPLLDKKKVVANTIYLGRDFHTLVIT
                     GPNTGGKTVTIKTVGLFALMTQSGLHIPADYGSSMCVYDNVFADIGDEQSIEQSLSTF
                     SSHMTNIVSILQNVTADSLVIFDELGAGTDPVEGAALAIAVLEDINSVGAKCIATTHY
                     SELKNYALTKSGVENAAVEFDIETLSPTYKLLIGVPGKSNAFEISRKLGLSDYVISRA
                     KEYINTENIALEDVLQNVEKNRIKAVEDREEAERLKEEIEKLKVEYDEKLEKLVSQRD
                     KMIEKAKSEAFSIIRQAKEEVDIIIKELRSLEQERASKEKNRKIEELRKELTSSMGSL
                     QPTVKSMIVPKVSNKEIKDLKPGEEVKVITLNQNGSVVSVDKKRKEAVVQIGIMKMTL
                     PFKSLQKTRKDVSTNVTKSTRNIIRSKSGSVKNEVDLRGLNLEEAIMEVEKYLDDAYV
                     AGLESVTVIHGIGTGVLKAGLQDILRRNRHVKSQRGGQYGEGGAGVTIVKLK"
     gene            57901..59352
                     /locus_tag="PC494_000908"
     CDS             57901..59352
                     /locus_tag="PC494_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-histidine dipeptidase"
                     /protein_id="HDF3911429.1"
                     /translation="MGNVLEGLKPESVFKNFEKISQIPRGSGNEKGISDFLLSFGKNL
                     GLETIQDESLNIIIRKPATKGYENCPGVVLQGHMDMVCEKEKNVEHDFLKDPIKLRID
                     GDMIYATGTTLGADNGIAVAMGMAILEDNTLEHPALEVLVTVNEEDGMNGADALDPSL
                     IKGQYILNMDSEEEGYLLVSCAGGKTCVVSLPVEYKEVKGDKQGLLVEVTGLLGGHSG
                     MEIVLQRANANKAIARVLSVLNVDYELASVDGGTKHNAIPREAKCVIAVNKADVESAK
                     KQINDILTAFKHEFTTSDPGMTYSVAETSVDKVLTKDCKEKVVQMSCLTPHGVQSVSL
                     DIEGLVESSTNFAIIETKESTIEFLTSVRSSVMSIRDEIADRIRLLAQALGANYDLIA
                     QYPAWEFKKGSKLEKICSETYEKLTGKVPTVMALHAGLECGLLLDKLPHAEAISIGPD
                     MFDVHTPNEHVSIPSVANVWDYVIEILKSMNQY"
     gene            complement(59556..62069)
                     /locus_tag="PC494_000909"
     CDS             complement(59556..62069)
                     /locus_tag="PC494_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HDF3911430.1"
                     /translation="MEDCVVNLKKLLLLIIVITSIFTSCIFSFGINAIGNDNRTIRVA
                     YPIQKGLTEIDEQGNYFGYTYEYLLEIAQYTGWNYEFVQVPGEINESITKLMKMLENG
                     EIDIMGGMLYNEPMQKIYNYAGNNYGVANTVLQALYENTDIDNIMSSQDVKKIRIAVI
                     ENSDTRLKELDEYCKMNLMSPELVYCKTNDEQLEALKSGKADVLLNVSMNPIEGVRTV
                     AKFSSKPFYFITPKGSTNLTQKLNSAINNIEQKDPYFSTTLYEKYFTPENNQMFLSDE
                     ETNYIKETEKLKVGVLLNKPPFQNIDKDTGELRGISIDLLNHICDKTGLEFELVPVKS
                     QEDLENMTKKREIDIVAGMIYDYEYSREHNIAMSRPFLSTQYTMMINNKLNENSLDGK
                     RVALAKGINYYGQFEENIVWYDNLEECIEAVNKGYADYTYGEGYSMQYYMNQPKYKNV
                     RLVPQTYKAKSICFGIIKKDKQELLNIFNKAIISISSEKMQSIVYQNTTYRQDFSLLY
                     IMQQNPIETIFIVASLLICIIGFMAFGLHTRTSMNEKISLELKKHTQLYEMTSEYFFE
                     YDYKQDKLIISMPEKGIETYYGLDKNDKESENGNIENERDKIRKEYNKKFFDVIKSQE
                     NGTTEMYSIMLDDTFHWIRVTSKIIYNDRKIPMYVIGKICNIDSEKEEKNRLLDKAQR
                     DSLTNIYNAAYIRKLTAQNLLNLSTEKNGALLIIDIDYFKSINDTYGHLLGDKVLIDV
                     AKVLDESFAKNDIVGRLGGDEFSVYINDIINKEELINKCNDVYNHIHLIKLPNGESLS
                     ISMGVVIAKPGQEYDELYQIADTALYDSKRQGRNRFKIV"
     gene            complement(62292..63113)
                     /locus_tag="PC494_000910"
     CDS             complement(62292..63113)
                     /locus_tag="PC494_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HDF3911431.1"
                     /translation="MIDINLEKCVGCGMCESDCLVNAIKVKDDKAKVKNILCINCGHC
                     MAICPTDAIEMQGFDKNEVIEYNRESFELEPEKLLNFIKFRRSIRQYKDIEVEEEKIK
                     NIVEAGRYTPTGGNRQPIRYILVKEKLKEVKELAIQGLYNLALDTDDNDPVRSMYKNT
                     FKKMYKRYKENGNDSLFYDAPLLMVVVGDMSLGGSAYVDGGLAASNMELMAYSQGLGI
                     CYNGFFVMASNVEPKIKELLGMSENEAVITSFILGYPDVKYKRTVNRNTAKFEVR"
     gene            complement(63632..64108)
                     /locus_tag="PC494_000911"
     CDS             complement(63632..64108)
                     /locus_tag="PC494_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HDF3911432.1"
                     /translation="MKLTTICYIEKDDKTLMLYRNKKKDDIHEGKYVGVGGKFEQGET
                     PEECVIREVKEETGLTLKSLSYKGLITFPKFKDEEDWYMFLYFSDEFEGELSEKDLND
                     CKEGNLIWVDNDKIFDLNMWEGDRLFLNWAKTGNIFSAKIVYDNGKLKDYNVSFLD"
     gene            complement(64143..64721)
                     /locus_tag="PC494_000912"
     CDS             complement(64143..64721)
                     /locus_tag="PC494_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HDF3911433.1"
                     /translation="MREEALEILFKYLETDRMRKHCYAVEAVMRELAKRLEPEKEEEW
                     AVAGLLHDLDSDIVGRKPGEICEGHATTTVELLKKENFGDEEMYRAILGHHDGMGVTR
                     TSLMEKAIYAADPITGFITAIALVYPDKKLTSVKTKSVIKRMKETRFASNVNRDAMRS
                     IEDIGIPFDEFAELSLNAMKNISDVLESAENN"
     gene            complement(64825..67425)
                     /locus_tag="PC494_000913"
     CDS             complement(64825..67425)
                     /locus_tag="PC494_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HDF3911434.1"
                     /translation="MKKIELLAPVGSFDSLKAAVQNGANAVYLGGKDFSARASANNFD
                     RNELIEAVKYSHIRGVQVFVTVNTLIKQYEIEDFVEYVKFLYDIDIDALIVQDIGMAR
                     LIKKLLPDFELHASTQMVAHSLEDVKYLQSVGFDRVVLARELNVDEIKWICENTTVDI
                     EVFVHGALCVCYSGQCLMSSMIGNRSGNRGRCAQPCRQKYELIDINTGEVVKSNGDYL
                     LSPRDLSTIEDLDKIIEAGVLSLKIEGRMKKPEYVATVVSGYREAINEFVDKKKISIS
                     EEIINNLYTIFNRKFTKGYILGEVGKDIMNSNRPNNQGLYIGKVLDYNRKNKRLRVML
                     ENTLKKGDGINLGGGTIGRIIKDGEITTIAHKGDLIELDFVGEAKRNQLIYKTSDSEL
                     MDRVQATFQQDKEFIKTNIRAKVSIKLGKKPELFISDFCGNKSVVEGDKIVEKAIKVA
                     LSKEKIETQIQKLGNTPYKLKEIEIDLDEGVSMPISVLNQMRRDCIELLDEERIKIKD
                     RKFKKNRLKYQPNRVNKQKKLDTAPKIRVKVKNLEQLEAVLNYNVDLIYYEDINTLSK
                     ALQMVSSISIDSNISIDSSISMDLDTSSSLGTPKELMGSNTNNIDTLSNTSKIDTLNK
                     NHYNTAVTDKKLIYSAPRIVRNKEYKQFEILDNIKGINKVQIGNWGSMEYFKKKDLNI
                     DCYLNAFNSESINHFKEEGASTVCLSQELNLNEIKQTLKYTDVEIEAVIYGYAPMMVT
                     EYCPMGVVVRDCKKDKRVAKCKESSYALRDFTDASYRITQDIFCRSTIYNSKVTCMLD
                     NLYELEEIGIDVFRIDFTVEDSEMVKKVIEAHIEVLSNNYKLGKKATDLYKKLDEIGT
                     VAGHYYKGVE"
BASE COUNT        21015 a        12646 c         7414 g        26490 t
ORIGIN      
        1 tataaaataa atatattata ttatacatat acttattttt actataaaag ttaaatttat
       61 aagcttactt gttataaaaa taacttttat aatttatttc aaaaaaaata ttgatttttg
      121 tgtcgcattt tgttataata aattaaggtt atccccctgg taaccctagt tagttaatat
      181 atctattccc aatacccttt cataaggata tattttatat ttattaaaaa tcggattagt
      241 aacggaaatt aattcggtgg aaaaaaagag cttaccccga gctctttttt ttctgcaaaa
      301 aatcgtaaaa ataaagttaa tattaatata actttaattt taaaattaat attaaccatc
      361 actaaaaaag gatgtattga atttctaata tcaataacat cctttttata taattatagc
      421 acttttgcta aaaatgcttt tgttctttca tgttttggat ttccgaaaac ttcttctgga
      481 gtattatctt caagtatact tcctccatct ataaaaataa ctctatctgc aacttcctta
      541 gcaaatccca tctcatgagt tacaattgcc attgtcatac cttctttagc aagttctttt
      601 ataacatcca aaacttcgtt taccatttct gggtcaagag cagatgttgg ctcatcaaac
      661 aacatcatat ctggttccat agcaagtgct ctagctattg ctattctttg cttttgtcct
      721 ccagataatt gtgatggata tgaatctttt ttatctaaaa gaccaactct actcaacaaa
      781 atttctgctt ttttttctgc ttcttcctta gtcatctttt ttaatttaat tggtgctaat
      841 gttatattat ctaaaatagt cttatgtggg aataaattaa agttctgaaa caccatacct
      901 atattttgtc taacctcatc aatattagtt tttttatcga ccaaattttt tccttcaaat
      961 attatttctc cacctgtagg tatttctagt aaattcatac atctaagaag tgtactttta
     1021 ccagaaccac ttggacctac tataaccatt atttcgcctt tagcgatttc taagtctata
     1081 ttttttaata catttaaatc tccaaaagat ttacttaaat tttttattgt aatcatatta
     1141 tcactttcct ttttactatt ctatgttttc cctaaatgct aaacatgctc tcatctagtt
     1201 agacacagat agtttctttt ctaataatcc aactaatctt gatagagtaa atgttataac
     1261 aaagtaaatt gctgctgcta ctattaatgg ctctaatgct ctaaatgctg cattttttac
     1321 tatatcagca gtacgcatta tctcaacaac tcctattaca gatattattg aagattcttt
     1381 tacaagtgta ataaactcat ttgctaatga aggtaatata ttttttatag cttgaggtat
     1441 tattatatat ctcatagttg accaataatt taatcctaat gatctacttg cttccatttg
     1501 tccattatca actgattgta tacctgatct aagtatctct gccacgtatg caccagagtt
     1561 tactgataat gcaaatgcac tagctataaa ttcacttggt ataccaaaca acatagggaa
     1621 tcttattcct aattgaggta aaccaaacca tactatatat atctgtacta ataatggtgt
     1681 ccctcttaaa acctcaatat agattgatga tattgctctt aatactttgc tctttgatat
     1741 ttttgccata cagataatta tacctattat aaatccaaag cataatgcca caagagaaat
     1801 tgatactgtc acacctgttc cttccaaaaa agaagtccca aatctactta aaaaactaaa
     1861 atctaaactc ataatttcat ctcccacata actttcttac taatttgaag cagcttcagt
     1921 agatgcttca tttaaaaatt cttctatctt cttgccatct tgtaattctt ttatcttttt
     1981 gtttaataat tctataaaat ctttgttatt gtcagatttt ttgattgctg ctgccatacc
     2041 ttctgttaca tctttcccaa cttcagtatt tgccattttt attccatcat attttttaac
     2101 atttattaaa gaaactgctt cattagtaac aactgcatct atgtttccat tttttaattc
     2161 tgtaattaaa tcaggtattg ctttcaaaga ttttgtagtt gtcattttta aagtgttaac
     2221 tacatattct tcttggatac ttcctgcttg aactccaact ctaagtttct ttaaatcatc
     2281 ttcagttttt actttgtcta tatctgcatc tttaactata actgcatttc tacttaaata
     2341 atataattct gaaaaatcaa cactcttttc tctctctggt gttggagaca tacctgcaag
     2401 aacaatatca acttggtctg catttaaagc acctattaat ccatcaaatg acatatcctt
     2461 aatttcaacc tttacaccaa gctcttttgc aaattcttca gccaacatta tatcgaatcc
     2521 ttttattgaa tcttttccat ctactacctt atgaaattca aatggaggaa attctgcact
     2581 agtaccaaca actaattttc cattgtcttt tatttgttct aactttgttt tttctcctcc
     2641 accactacat cctactagcg ataatgtcaa tcctaatact aatcctaaac ttaataattt
     2701 tttaaatact ttcattttaa ctacccctct cttttaatta taatttccct cagattttaa
     2761 tacttaaatg tttcgagtta caaaaaaagt ctctcagtct ttaatgacta agagacgact
     2821 ttaccgcgtt accactctta ttgataaata cttatattac tttcaaaatt tgtgactgtt
     2881 agcatttaag ctgtatggat atttttattt ttaaatcaaa aaagtccctt agctttacag
     2941 ctaagagacg aattatatcc gcgttaccac tctttttgat aagtaagtac ttatcctctc
     3001 aatcccttaa ggcgggtaaa ccaattatca tactaaagtt tctgataatc tcctccagag
     3061 ctctcttcac atagacttca ttgctaggct tacaccaacc cctaactcgc tgtaaatcca
     3121 tatatgctac tttctctatc attggatttg tttccttaaa ttgttaatac aattgtactt
     3181 ccttataata tttttgtcaa taagtttttt atttttttaa taatttttac ttgtaaatta
     3241 tctaaatact actgtttata tttattgata ttagttttgt aattataaat agtatatttc
     3301 atatttttag ctatttctta aataatacta aataatatct ttcacattgt tgctttttct
     3361 taaattacac taaataatat ctttcacatt gttgcttttt cttaaacaat actaaataat
     3421 atctttcaca ttgttgcttt tcttaaatta cactaaataa tatctttcac actgttgctt
     3481 tttctttaat aatactaaat agtatctttc acactgttgc cctttcttta ataatactaa
     3541 ataatatctt tcacattgtt gctttttctt aaattacact aaataatatc tttcacactg
     3601 ttgctttttc tttaataata ctaaatagta tctttcacac tgtttctctt tctttaataa
     3661 tactaaataa tattttccac attgttgctt tttctaaaca actataaata atatattaaa
     3721 cccttatttc tttttctaat aagttaaata atacatttta cacatatcta tttgtcttgc
     3781 acataataaa taatacatta tatttctatc taaatttaga ttctaaatta aatagtataa
     3841 attatattct tcaataaaca agttttcaaa tccaagattc gctctctatc tttaaacttt
     3901 attgtaaaca taattccatc ttttttaatt atttctcctt catgaaattt tttatggtat
     3961 accttatccc ctacaccaat actgtcaatt tcttttttcg ttggagattt tatatcatta
     4021 ataaataatg atttatcaac tttcttacca tacttattta aagtagagct tatacataac
     4081 ttttcttcag ctcttgtaat agcaacatac ataagtcttc tttcttcttc taattgttct
     4141 tcttttttct cttccttaca aatatcatat gatttttcat gaggtattgt tccttcattt
     4201 acacctataa tataaacatt tctaaattct aatccttttg cactatgcat agttgtaaat
     4261 atgacaccct cagtctgctt attcttgtta ttttccgtta actcagtctt tactctatca
     4321 atatgctcta aaaactctgt aacagtatta aaattagttg ctgaactctc aagttcattt
     4381 aatatctcta caagtccatt agtctttatc tttctgttgc tacaataatc taaaacatat
     4441 ctatcataat caagactagt tctaatataa gatattgcat ttttaggatt taaagtattt
     4501 aaataactta aatctatttc caaatcattt attgttttaa cttgtttagg atgaagatta
     4561 cacttattta ttaatgctgt tataaagtct ttttcatcct taaccatatt tatactgtct
     4621 ttggatatat atctaaaagg cttgtttata attctcaacc aatctttatt tgattttgga
     4681 ttaataccta ttcttaaata ggctagtatg tcttgacttg cccaatggtc atatattgta
     4741 attactgagt cttttactac aaatggaatc ctcatatcca taaatacatc tactaatgct
     4801 cttgactgta tattagttct ataaattact gcaaaatctg aatactctac ataatctttt
     4861 tgtatttcgt caattatttc cctggcaata tataaggctt cttcctctga atcatgcgga
     4921 gaaatatagg taacacttcc tccatccccc tgactacact taatgatttt ttcatatcta
     4981 tttttatttt tgtcgataag tctatttgca gtatgcacta tctcactttt agacctgtaa
     5041 tttatatcta atattatttt tttagtatta ttaaagtatt gttcaaattc aagcaaaaaa
     5101 tctggtctag cacctctaaa tccatatata ctttggtctt catctccaac tgcaaatata
     5161 ttgtttaatg ggctacaaat taactttaaa acttcaaact gtactttatt tatatcttga
     5221 aattcatcta tcaatatata tttatacaca tttctaacca tttctagtgc agacttattg
     5281 ttcaaaagta aataataagt tcttataagc atatcatcaa aatctatttt attaacttta
     5341 gatttttgtt cttcgtataa gttgtatact tttaaaaact catcttttgt taatacttct
     5401 gaattaaatt catttttatc cataagttca ttttttacat aggaaatttc atttataact
     5461 tgtcctatat tctcatcatc atcagcattc tctatattta aactttttag gattgccttg
     5521 attgtcattc gctttgactt ttcatcaaat atactgtcta agttgtatct ttcaaagtat
     5581 cttagaattt taaaaaatac agagtgaaaa gtaccatagg ttaccttatt aagtcttatg
     5641 tcatcactta aattcaaagc tctatttttc atttctattg aagatgcctt ggtaaaactt
     5701 attgccaaga ttcttgttgg tgctatgttt ttgtttacaa ccatattggc tattctatat
     5761 gtaattactc tggtcttacc tgaaccaggc cctgcaagta tcatgcaagg cccatctata
     5821 tgctcaactg cttctaattg attttcattt aactttctta tatctatatt tgttgtgatt
     5881 attagctcca ccaccttgat ttataattat attattttct ttttaattat aaactaaaag
     5941 ttcataaaaa taaatttaat ttttcctcta ttaaaccaca tcattcctat tttcatgaca
     6001 tatcttgagt tcttttttaa ttttgtcgct tatatcttca ggtataaatg atggtttact
     6061 aatatagtag ccttgcatat aatctactcc aagattaatt agtgtttcca tttcaccttt
     6121 tgtttctaca ccttctgcta tcactttaat atttctttcg ttagaatatg agataagatt
     6181 ttttaatatt ttctgtctgt tttcatcttt atcaatacct cttacaatag acatatcaat
     6241 ctttacatag tctggcatta tatataatag tacagcatct ccgttgtaac ctgtcccaaa
     6301 atcatctaaa gcaatttcta tattccaatg gtctatatat gctttctttt tctcaataaa
     6361 atcttcatta atcttatcat tctctgttat ttctagtact actctattta aatattcacc
     6421 atataaatct tcaatttcct caaaatctac ttttgacaaa ttattattag gaatagaatt
     6481 taagaacagt ttgcaatcgc caaatttttc tttgtatttt ttaaatgatt taagtgcttt
     6541 aaaccatgta atacgctcaa tttgatataa tttagactgt gaacgagcta atctaatgac
     6601 atctattggc gaactaaaag tttttatttt aggtctcata agtgcttcat atgcaaatac
     6661 tttaccttta caatctacaa taggctgaaa tgcatactca actaattgac catcaattaa
     6721 cttgtttaat tcttctctat tactcaataa gaatgaatcc ttattatata tattaatatc
     6781 aaattcacta acttcaccct tgattgtatt tttaatttga tacatagcaa aatctgcgta
     6841 tctcattaat tcatcatagt tggttgaatc atcagggtac caggaaattc ctgctgatgc
     6901 ccttatttta aattctgttc catcatgaag ttttaataag gtattattca tctgtttctt
     6961 aacagaatta ataatatctc ttatactatc tttactttca tatccatata taaatacata
     7021 aaactcatca cctgaaagtc tagatactat accattccat gatataaact tcttaagtat
     7081 gtctgcagca cacctaatat attcatcacc agcatcatgt ccatatgtat cattaatata
     7141 ttttagatta tctaaatccc acataataaa tgctgctatc ttaagttcat ctttattctt
     7201 aaatttttct tgtatctgtg aatgaaaagc tctcctattt aaaagattcg ttaaaatatc
     7261 aaaatctctt tcatattcta tcttcctttt ctcaataaat tcttttgtta catcaacaac
     7321 aacaccaaga acctttagct catcttcaaa gatattcatt cttatccact taagtttttt
     7381 atctttagat tcaaacttat atatatatgt attttctgtt tcataacttt cttgcaaata
     7441 tttatctagt ccccttaatt ttttcaggaa cttatttttt tccatatatc catattcttc
     7501 aaatttgatt tcagtagtaa acacgctaaa aaattctttt gtacaaaaaa cattctctgc
     7561 gtttttgtat aactcaaaag ctccaattgg catatctacc atttcaataa tctgtgataa
     7621 ttttgacgaa gaatctgcaa catttgcact gagcaactct atagctgaag ataattcatc
     7681 tatttcagat atatttatct tatcaagatt tactggtttt gatggattac tgtttctaac
     7741 tttgttggct aaaagaacaa ttggttttgt aaataatctt gatgcaatgt aaatacctat
     7801 tagacctatt aataaagaaa ttgctataga tattataact aatttctcta ccctttttga
     7861 aaatgacaaa agactttttt cttcaataat acccaaaaga gcccaacgtt cattttcaaa
     7921 tggagtattg gagttatata aatctaagta ttgtacacta gcataaatgt tgccattacc
     7981 acattcatta tctttatttt taatcttata tatattttta tacgattcct tctgctctaa
     8041 attagaatgt aaaccatccc aaaatttttc ttttaatgag tatccatttg aaattacatt
     8101 ttcaaaggcc atatcattat ttctatctac acctaaaata taattaccct ttttattccc
     8161 atttatctct gagtatggaa gtaattctct taagtaattt acacttaaat ctattccaag
     8221 tactccatat acagttccat cttcataaat aaggggaact gtatatgtca taagcctatc
     8281 acctgcattt gtcaataaaa acttacttcc ccagtatcct aaattagaac ttgatacatt
     8341 tggattatca attgcagctc taaatggttt ataaaaaaaa tcatctccat cttgctcatt
     8401 ttcactttta aatgaaaact taggttccca ataactgtcc atagatattc caaaacttct
     8461 tgctatatct gatgaacctc tctcaattaa caaatcagaa ttatcatttg gattaaactt
     8521 agggtctaaa tcccttatat acaatcctgt cctacttatt tcacctttac tatctattga
     8581 cttatcgtta atatttttgt cacttaggat tataaaagct cctgtaacag aattttttct
     8641 caaaagatat attaaatcat ttgatatgct ttttataata tctttgttaa tttcttcatt
     8701 gttgcctaca tcctcaatta aggcattttt ttcatttaat acttttttta cagaggaatt
     8761 aattgtagct tccgtttcac ttgtatttga ccatctttgt aacatttcat tttgtatata
     8821 atttttacga ttaattactc tttcatttaa gatgtcaaac gaattatcat ttaatttctt
     8881 aatagttcct ccccataaaa ttgtggcaca aaataaactt gtttgaatta gcataacaat
     8941 aattagggga aatatcatct ttttcattat tgaattgttt tttcttagat tgttttccat
     9001 acccattcca cctatacctt tgtgctcgtc aacacactaa ctgccaattc atctattttt
     9061 ttatagcatt ttcaagctca gccttaaaac tttcaaacca agttttaaaa tttttatcat
     9121 tattaaattg tgctactgca tccttcttag aagttccact ttttactaat tcatttattt
     9181 tatttgaatc ttctttagct ttatcaagca ttgaatattc aagtatttgt ctagctttag
     9241 ttccaccatc aaatgcttta ttagtatata aattacaact gttaatctgt tcaatagatg
     9301 aggctattga accttcaact ttatcagata aactcaaatt atctttcttc ataacttctt
     9361 ttataacatc caaatcattc gtttttttct ttactggtaa gtatccagaa gcaatagaga
     9421 attttatatt aggttcttta tctgtaaacc attttaaaaa ttctactgat gcatattctt
     9481 cttctttagt agattttgtt acagccattc ctgcaccttg ttgtacagca tattttcctt
     9541 ctcctttaaa acgtggtgct tgaaaaacag atgtttcaat attataactc tcattatcat
     9601 ttagcattac tctatctgga aagtatgctg ctcctgaact agaacctaca agagctaata
     9661 tatcacctgt ttttgcatca tcagaacgaa acttaccata agaagcaaaa tatccattta
     9721 tatatggtac atagaaatta tcccatagtt ttttcataac tttttcatca atatttagtg
     9781 taactttacc atctttaaca gaaaaaattt ctactcctag ttgtttactt cctataataa
     9841 tataatttgc taaagcatct cttccaaaaa atgctttacc atcattaggc tctttcgtta
     9901 aactatctgt ccattcataa tatttttttg atgtctctac taatccttca attgttttta
     9961 tatcatttat atttgaattt gtagcttttg caaatttatc ccaatcagtt ttatttaaca
    10021 tcaaaatttc agttgatttt gcaattggga aaagtttaaa ctcatcctta gaatttattc
    10081 tgccttcttc tacatattcg tctatgtatt catttaattc ttctttactt atgtacttat
    10141 ccatatctac tagtaaccct aatttatcca tttcatatgc agtatctgag tatgctgcaa
    10201 atatatttgg tacatcttca gaaccaactt ttttatttgc agaatctaaa actttctctg
    10261 ataaatcaac tacattacct tgactgaatg cttcaacaat aattcctttt tcagcaccta
    10321 cagtgtcatt aaattcctta acaagcttat caaaagccat tttctgctgt ccattataat
    10381 aatgccaaat ttgtattgat gtcggatttt ctgggtctaa cttataatta tcttccttct
    10441 ttaaactaca tcctgtaagt aataaaacaa tcattgatgt gataattaat tttgcaaact
    10501 tacacctatt cataaaatct actccttcaa attataaaat ttataatagc attaaaactg
    10561 taacttcact atttatatta attatagaac gtttattgat atatttaaac aggatttaca
    10621 acatatttaa aagcaattaa gaaacatact attacaaata tagaaaataa agcttttaca
    10681 taatttttat ttctaaatgc gccaaatgac accaatcctt gttgaatagc tactgtaatt
    10741 actaaaagta tcattattat attaagttga accagtttaa ataagtaaag caatgaaaac
    10801 actactagaa gtacacataa tacaatacta gatttattaa taatatcatc aatcttatct
    10861 accttcttag attgcttatt aactttattt aatttttctt tatttaaatt ctcaactttt
    10921 ttattatacc tttctcttgt tttatcttta tatttagtat ttttattttt atttcccatt
    10981 tattttccat cctctataaa ttttttaatt gagcttatac attatttaaa tattatatat
    11041 ttaagatacc atatattcct acaaaaaggt aacttactat gtatctattt ttgattttcg
    11101 cataaaaaag ccatctcctt tagaattaat tctgtattga gacagctaat ttaactattt
    11161 atcctttgaa acattttcta cattatcata tttactatca actaaaacta tatcaactct
    11221 tctatttttt gacctacctt cttcagatga attttctgct attggtctaa actcaccata
    11281 tcctacagca gataatttat ctggtgctat acctgcattg tcaataagaa gttgaacaac
    11341 attggttgct ctcataactg ataaatccca atttgactta aactctgaat tttttataga
    11401 catattgtct gtatggcctt ctactctcat gtaactattc atttcattta acatcttacc
    11461 tatttgaata atcttatctc tagaattatc cttcacaatc gctttccctg tatcaaatag
    11521 tattgtatct ttaaggctta ttactaatcc tctatcttga actcttaatg atactgaatt
    11581 agccatacca ttttcattta aatacttctg gatttcttca ccaacttttt taaacttagc
    11641 attttgtaaa gtatctaaat cattacttcc tggttcaact actggttcta tcttgctatt
    11701 accaccttca ataactccag aagaaccacc aaaagcagaa tttagagatt gagataattg
    11761 tttatatttc tccgcatcaa cattactcat agaatacatt attacaaaga aaatcataag
    11821 taatgttatg aggtctgaat aagttaaaag ccatcgctca ttgttttctt ctttttcatc
    11881 ttcatcatac aacataaaca ttccatcctt ttatattatt cagctctacc accaatttct
    11941 tcaagttcaa ttagttcttt tgaatttaaa aatattttta atttttctgt cattaaatta
    12001 gaattatcac cttcaagtat ggataatatt gcttctatca ccaaaagtct ttcacttatt
    12061 tcctgttgat ttatagcctt aagttttgat gctattggta accatattaa attggcagaa
    12121 ccaacaccat acaaagtagc caagaatgca acagaaattt gaggtcctaa tgcatctgga
    12181 ttacttgaaa gattacctaa aatatgtact aaccccataa ctgtacctat tatccccagt
    12241 gtaggtgcat atccccctgc tgaatcaaaa attgctattc cttctttatg tcgttttgat
    12301 gttatctgta tctgtgattc caatatattt cttatagtaa ctgcatccac tccatctacc
    12361 ataagttcaa gcccttttct aataaaaggg tctaattcat cattctcact tatttctttg
    12421 tcaatactaa gaagcccctc tttcctagcc tttgttgcaa tttctttgaa atagattata
    12481 ttttctatgt tattaggctt tttattttta aaagctaata acattatctt tatagacttt
    12541 ttaaacacag ggaatggagt cgaagctcca acagctccta tagttccacc aaacacaaca
    12601 agtgctgatg aaaatacaaa taatgctcca acatgtcccc catcaataac aaaagcaact
    12661 accaaagatg ctatccccac tatgaaaaaa attaaagttg tcatctattc cctcctttct
    12721 ttagttatac atatctaatc atttatgaca ttataaaaag actatcttta ataaaaatag
    12781 cctttaataa ttggcggaga aggagggatt cgaaccctcg caccggttac ccagcctaat
    12841 cccttagcag gggatcctct tgagccactt gagtacttct ccatatctct atactagtaa
    12901 attatataat aaaatcatat tttagtcaat tgttttataa aatttgagtt attttgaatt
    12961 attaaacatc tatttttact tttttgctta aatgtaagtt ttaaatatgg taaaattatc
    13021 ttgcataaca cttataatat tatttgataa atatacatac attaacaaat atacctaaac
    13081 tctgacttaa ttgtaagtta tgccaaaact aaaataatac tagtccaagg aggatatttt
    13141 atgttaccac aggaaagata tgagaagatt ttaagtattc tcaaatcaga taatataatt
    13201 aaaataaatg acatagttca aatgtttgat atatcaatag aaactgcacg aagagattta
    13261 gcccatatgg agagtatcgg tcttttaaaa agagtttatg gtggtgctat accagttata
    13321 gcaagtagcg tagaacttaa ctatgttaaa agaaaaaaaa taaactcaaa cgataaaaaa
    13381 cagattgcta ttaaatgtag tgagtttata aatacaaatg atactatttt tatggatact
    13441 ggaactactg tacttgaagt ttcaaaaaat ttgaaagata aaaagaatct aactgtaata
    13501 accaactcaa ttttagttgc aaacgaactt atgaatacta atataaaagt atatgtgctt
    13561 gggggctatc ttagagaaac tgaaggttct ttttctggtc cgcttacact gtcagctatt
    13621 gaacaattta atgttgataa agctatttta ggcgctggag gtatcactct tgaaaatgga
    13681 atctctgact atcacttaga agaagcactt gttagaaaaa aaatgattga aaggtctaga
    13741 aaatctatag tagttgtcga acctcctaag tttggtataa attcatttgc atcagtagct
    13801 cctatagaac atatagatac tattattacc tctgctagta tagaccataa tataataata
    13861 gagttttctc aaaaaggaat acctttagtc atagctgata attagcttat atgattgatt
    13921 tttagttcct tgatgtaata aattaaaatt aaggagccaa ataattattt atttagctcc
    13981 atttatgtct aaactatact ttatatttta attatgtaac tactttcagt tagcttatca
    14041 tttttagtta tttgattgcc attttattta atttataagt tttagttatt cgattatttt
    14101 ttaattgtct gtctttttaa tttattttta gttatttaaa ctcctacttt aaaataattt
    14161 aaatttgact taagtattgt ttattctaca ctgcatcttt cttcatttta atactttgtt
    14221 cttcttccaa ggttaaatct tttgtcataa gtatagcaag tgcaattgcc aatactcctc
    14281 caaccaattt tccaattaca acaggtgtaa tcatctctgg aactactcct gctgtaaatc
    14341 ctaaatggtc ccccaaagct gctgtagcac aaaccagcca agcagtattt actactttcc
    14401 cctttggact catatctttc atcattttat atactggaat actattggct aaagtaaaaa
    14461 ctaatcctgc tgcactagtg gcatccatac ctaattttcc acccactatt gtaagtggtt
    14521 tattaagaac tttaactaat aaatgtaata ttggaaaagt acctaataac acgattgcaa
    14581 tacttccaat tacttgaata ccttctctta taggtgtcat gccttttata agtactatac
    14641 ctgttatttc ttgaaatgct gctgctccca aacctatcgt tatcaatata gatataaatt
    14701 ttccaaaaat taatgaccca tttatcataa gcgtagaatt aaattttaaa cctactgcca
    14761 atatcactgc caatattatc actggtatca tatttataat taccattgat aagttaaatc
    14821 ctgctattaa tcctcctata atacctccaa aaggtattgt tatcaagcct atcagtaacc
    14881 cttttgcaaa gaatggtctg tcttcatatt ctataagacc tagtcctact ggaattgaaa
    14941 atactaatgt acatccaagc atggatgaca caaccaatcc tgcaagcatt cctgcctctt
    15001 tattgtgtgc aagttccata gccaatggat accctcccat atcattcgct aaaatagttg
    15061 caaacataga tgggtcagct ccacagagat tgaagattgg tattattata ggacctagta
    15121 catctgaaat tactggagct aaacaaacta taccaaccat tcctaaagcc aatggaccca
    15181 ttgaattaaa cccttcttca aactgctctc caagtccaaa tttatttcca attattctat
    15241 ctaacgctcc taaaagcact cccacagcca ttatgtataa tataatttta tcaaagggca
    15301 tttttaattc ctcctataca tgtaaaatac tctattgtaa cttaattagc acacaccttt
    15361 ttggtatcgt tttcccaatt catagctctt tttactgctt gattccatcc aagtaatatt
    15421 tcttctcttt tttgattagt catatttgga atatattttt tgcttattgt aaattcactt
    15481 ctaatttcat caatactgtt ccagacacca caagaaagac ctgccatata tcctactcca
    15541 agtactgtcg tctcaggatt ttctgcaatt tcaattggta tacctaatat gtcggattga
    15601 aattgcattg taaagttatt tttagtaatt ccaccatcta ctctcaacat ttttattttt
    15661 ttccctgagg ctaagttcat agaatcaaca acatctttga cttgaagtgc aacagactca
    15721 agagtcgctc ttactatatg ctctttttta gtacttcctg ttatcccaac cattgtacct
    15781 ctagcatatt ggtcccaata aggtgctgct atacctgcaa atgctggtac aaaatataca
    15841 cctccagtac ttgatatgga atttgccatg tcatcagttt ctgaataatt ttttataact
    15901 ccaatgccat ctctaagcca ttgtattgca gcacctgcta tatacactcc accatcataa
    15961 gcatatgtaa ctttatctcc tattttccaa gcaacagttg tcaaaatacc attacctgct
    16021 atatttagtt cctcacctat attcatatat aggaaacatc ctgtaccata agtattttta
    16081 accattcctg gttcaaaaca tccattgcca aataaagctg ctggttggtc taccattgaa
    16141 gcagtaattt ttatagaaac cccacaaaat gcctccttat ctgtagttcc aaaatcacca
    16201 ctcgtaggca ttatatctgc taaaatactt ctaggtattc ctataatgtc aagcaactct
    16261 ctatcccaat ccatatctct tatattaaaa agcattgttc ttgctgctgt agatacatca
    16321 gttaaaaaag attttcctcc tgtcattttc catattaacc aactatctaa tgttcctgca
    16381 agtacttctc catttttaat tttttctttt acacctttta cattatctat tacccattta
    16441 atttttgtac ctgagaaata tgggtctata attaacccag tcttatctat tatcttattt
    16501 tctaaacctg gtatattctt taaattttcc acataatcat aagttctcct gcactgccac
    16561 acaatagcat tgtaaagtgg tttacctgta tttttatccc ataacattac tgtttcacct
    16621 tgattatcta taccaattcc ttttatatca ctttcattga ttccattttc aaaagcctgt
    16681 tgtaatacat tattactcac agtttttgta ttattccaaa tttctatagg gtcatgttca
    16741 acatatccag attgtggata tatttgagta tgttccatat aatcgctaaa aacaaactct
    16801 gatttttcgt ttatcaatac tgctcttgtt cctgttgttc cttggtcaat tgctaataca
    16861 tatttcactt taaatgtccc cctttatttt cagaattaac aaattctttt ttattttttg
    16921 aatatataat ctattcaagt tatttatatt ttatatcatc atgtggattt atgcaatatt
    16981 cattacaata ttttttgtta tttttaatta tagtgattaa aaaagtattt ttattgaaat
    17041 attattgcaa tatttattat tttattctat aatctagtta aaataacaca taacatttta
    17101 atatttacac ataatcagtc attcaaaaat ttaaatttaa ctttttaagg aggctttaca
    17161 atgaaaaaaa catatctatt cagtcctgga ccagtaatgg ttacagataa agtcagaaat
    17221 tcacttcttc actatgatat atgccataga ggaaatgagt ttatgaattt attcaaagat
    17281 acacaacaaa aaatcaataa actatataat gcaacttcta attactactc attaattgta
    17341 tctggctctg gaacatctgt aaatgaatgt gtactatctt ctatctttga caaagaagat
    17401 gcagttctgc tagttagtaa tggtgttttt ggagaaaggc tagaagaaat attatctact
    17461 tataatgtaa aaacatataa acctaatttt gaatgggcag aatacccgga cctagacatt
    17521 ttagaaaaat acataattga aaattctgat ataaaagtaa ttgctatggt gttccatgaa
    17581 actagttcag gaatgataaa tcccgtccct gaactaggaa aacttgctaa gaagtataac
    17641 aaaatatttt ttgtagatgc aataagtgcc tcagcaggtg aatatattga tgtggaagag
    17701 tttaatatag atataataac aggtgttggt ggcaaagctc ttggagcatt tccaggttct
    17761 gcataccttt gtgctaaaga gagtatttta caaaatatta aagaaaatca atgtaagaat
    17821 gtgtatctta atctttataa acactataaa gttgctaaat catcttctca aacaccaaat
    17881 acacctaatg ttactttaat atttgccctt aatgaagctt taactgaatt tttggaagat
    17941 gacagtaaaa tagaaagata caaagaatgt tctgctattt taaggaacgg tatggaagaa
    18001 ttgggtctaa catttttact tccagataag tatatgtcta atacagtaac atctgtattt
    18061 ctacctaaag aaatcaatgt aaatgagttt atattagggc tagaaaggga aagtggctat
    18121 gttgtctatc caggaaaagg caaattccta gatgctaaca tattccaagt agcaaatatg
    18181 ggagaaatat atccagacga ttgttataaa ttcttagata tcttaaaatc aaaattggag
    18241 ataaaaaaag ttatataaca gtttgtttgt aaaatcctac aatatatcag tataaattaa
    18301 atagactgat ttttttaaat tttcctataa taaattatat tttatatttt tgtataaggg
    18361 tgaactataa tatgtaaagt tcacccctat ttcaaatctt tttccttcaa tataatcttt
    18421 ttcttttaat ttattttata tttttgacgc aatcgttttt tattcaatca ttttatattc
    18481 ttgatacaat cattcttaca cttaattatt ttttgttttt gacacaatcg ttttttgttg
    18541 aatcatttta tattcttgat acaatcattc ttacacttaa ttattttttg tttttgacac
    18601 aatcgttttt tattcagtca tttaatattt tcaacacaat cattcttaca ttctattatt
    18661 gtttgttttt gatacaactg tttttattca gtcatttaat attctcaaca caattacctt
    18721 ttcattcaat caaagtaatc tttaagcatt atttttcaag ctcatcaaag taattatata
    18781 cgataacctc acctgtctct ttatctgtag tctttataat gcccttagct ccatttacct
    18841 cttcttttgt aaattcatca tctaacacaa ctttgaattt atcttccttt ccataacctt
    18901 gttgaaattc atctctcaaa attgcatttt tttctgcttt tggcttcaac tcaaattcaa
    18961 ttccagattt catttcatca aaataattta atactacaac ctcattattc attttattag
    19021 ttgtctttat aatcccttta gctccattta cttcttcttt tgtaaattca tcatccaatg
    19081 ttatattaaa tttgtcttct tttccatatt cctcttgaaa atccctcttc atttcattgt
    19141 atttagtttc aaactcttta ctcttgttta attccatagc tgatacattt gtcaatgatg
    19201 ctccaattgc cattactgtt aatgccatta ctataccact tttaaatttt tttactttca
    19261 tatcttacct cctaaattaa atgttctcaa tgaaattata taaagaaaat cctaagtttt
    19321 acagtttcat tcttgtaact aaaattacta ttatgtaacc aaactttttg cttcaactat
    19381 tccttaaaag ttgctttttt gaggaatagt tgaagttaaa taattagatt ttatctatat
    19441 ttatagattt aaaatcaaat ttatccatat aaataaatac ttatttttgc aaaataaaaa
    19501 tttttaatta ctccaatcct tcttatttac ttaaaattct atgataagaa atttaaaagt
    19561 ctttaccttc tttaacaata atttatttac ttttaacata caaaatagag agagtatatc
    19621 aaaatcattt tactgaatat tctaaaaata agtaccccct attagtatat atatttacat
    19681 attaaaaaaa agttttaaat aaagttatat tttttacaac agttttgtaa ttaaaaacat
    19741 attgaaggta aatttaaagg tactatatac tataaatatg tcgacacaat aaatttaaaa
    19801 aggagaacta aatatgaaaa aaagattaat aataatgata ttgtctgttg tcttagtact
    19861 atcaagtata cttacgatat ttgcatattc aaatattaaa tataataata acaaattgat
    19921 atattctaat atgatagata aaaaaactca aaatagtgta aaggaaatcc taaaagaaaa
    19981 taaaattaat gaaaaagaca tagatacatt tattaaagca gtcaacaatt ataataaatt
    20041 gcaagttaaa atacttcaaa ataatataaa tatatctaaa tctggatatt cttcaatcaa
    20101 tgcaaaacaa gttccatata acctagaaaa attgcaagat aattgggtga aaaaattccc
    20161 tgattatatg gatgtaaatt gtagaataac tgcttttaga ctttttaaag attttataaa
    20221 ttcaaataag aaatttactg gagactctat tgatttgaat gtcgacttgg acactataat
    20281 gaataataaa gatgctaaat ttagcaccaa agatgtagaa aaatttatta acttcttttc
    20341 tgcaatacca gctaaagaca cagatgatac aatcaaaatt gcagaacaaa taaaaaatga
    20401 atggaaaaaa agaaaaatat cttttaaaaa taataaaaat atatctatta taaatggatt
    20461 tcttcgttat ccagaaacta aaaacgtatt tataggtcat acaggcatat gtattaaaac
    20521 taaaaatggc attctatttt tagaaaaata tggtgttaca tcaccttatc aagttactaa
    20581 atttaaaaat aaagaagatg taaaaaatta tatgtttaat agattgaaga tgtcagaagg
    20641 tgaaattgaa ttacctgacc ctataataat ggaaaacgat aaacttatga aataataact
    20701 ttaaacgcaa aatagtattt ataattacta agtcaatata atagagaagg tctatagatt
    20761 tgtgtaaata caagcttatc tacaatctta tataagaatg tttatataaa taagatagat
    20821 taatcctaag tcctattatt ctattgaatt ttattattat tttatttaga ttctattgtt
    20881 attttactta gaacttatta ttattttatt taagttctat tactattttc aatcatataa
    20941 atttacaaaa gactgtacat aaatttattt tatacaaact tatctacagt cttttgtgtg
    21001 aatatatcta aataatatcg tatttattta tttcctctgc acagtgagaa tcagaaccta
    21061 aaactaatgg aatatcgtat ttttttacca actctaataa gtatccatct atataaggct
    21121 ctttgcagta ctcttttcta tttccagaaa cattataatc aagttcataa cctttttctt
    21181 taattaactt tattaactct tcaagaattg tatttccttt ataatcgtat ggaaatacct
    21241 gattaaactt tctaactaaa tttaaatgac ctattctttt tggtttatgt atacctaaat
    21301 ctgaatttac agcttttatc aatgtttcat aatacttatt ataaacagct tcaatacttc
    21361 ctaacttgtc gattaaattt tgaaactcct ctacactgta atctacacaa taataatcat
    21421 catcaatttt aattatatgt actgataaaa gagaatcctc taattcttct ccatatttat
    21481 ttaaattcgc ctttatccct tcttcgtatc cttctataaa atccacttcc gacccaacat
    21541 ttatcttgat tttaccctca tacttttctt tcaacttctt gacatcatta aaatactttg
    21601 gtaaatcttc aatactcata caactatcat tttcaggagc agggtctcta aatccatttg
    21661 catacggaaa atgttctgta aatgtcattt ctgttattcc aacatccatt gctctttgta
    21721 catatttttc aaaatcatcc ttacttccat gaggacaata aggtgaatgt atatgaccat
    21781 ctttcataaa taattcactc cttttttaaa gaaaaaatct aatataaatg cataaatctt
    21841 ttaacttcaa aataatattt ttaatcatgc taatttttat tatatctaat attagagtaa
    21901 ttttaaactg ccttttaagt atcttatcat tagtactatt ttcaacttaa cattaatatt
    21961 attttttaac ttaacattaa tactatcttt aaatagtaat actcaatata taattactta
    22021 acataaaata actcaaattg cttgatgagg cttttgcagt atttaaagaa tatataatta
    22081 tttaacatta aattatccaa tcttgtaata aaatttactc attaaagtat attacagaaa
    22141 atacctcaaa ataaactttt tagttcatga gatactcttt tttacatgaa attagatata
    22201 tttttatcat ttcaacaatg aaagggaggc ttatatccat ctttagacaa ccccttagat
    22261 aaaattttta ataattaagc atcacaaaat ataaaaatcg cttatatcaa acgtataagc
    22321 gattaattat atttacatat gttttttagc ctctaacaac attttattag cttcttccat
    22381 atactctata gccttttcaa tactctttgc tgtttcttct tttccaatag ctctagcctt
    22441 ttcaacccac tctctaaatc cttcttcatg agtttcattg tgatttatcc aatgtactaa
    22501 aagtattttt aaagtttttt catccttaga ctctgatgat tcctcatgac tatgttcgtg
    22561 gtcgtggtcg tgagcatggt catgtggatg ttcatgacat atatctccat gagtatgttc
    22621 gtggcagtgg tcatggtcat gatgtccatg atgatatctt acaatctctt tatcaaaaat
    22681 cattagttat tccccctgtt attttatatt aaactctttt tttataaggt ttacagaatc
    22741 ttttacaagt agtgctaatg gtttaccttc taatccaact aactccacat tttctggcat
    22801 aataggtaaa agtatcttaa gtgcctcact gtctgcaata gcttcactta tattacaagt
    22861 aacttctccc atcatagaat taggtattat tacagaaata ggtgcaacta ttatatttgc
    22921 ttttttagct gatactacta tagcattttc ccctgtagct cctttattag catgagcttt
    22981 catcatagaa ctagttgcta tagaattagt ccctagtgca taaatttcta catatgtagg
    23041 taactcttct ctcaaagaag aaactatctg ggctccaata cctccaccca ttccatctat
    23101 cactgctatt atcatatgaa attcccctat taattaattt tcttgtatta ttatcttatg
    23161 gtccatcaat cttatttctt taattatccc atctattatc ttttgctctc ctaataaatc
    23221 cgttaaataa atctttccat cacaagggtc tatattaacc acattttcca taaccttttc
    23281 taactcatta ttacttttac aaatgaaagc tgatgattca cacatataaa tctcctccta
    23341 atatgatttt tattaaaaat caaaaaaaga ttcccttagg tatttcaata caccaaagaa
    23401 accttcatga tttcagtttt tgtatattat tataccttaa gtatatcact ttaatttatg
    23461 taaagtcaat taaagttaac gctttttatt atactcttca ttcttgtatt tttcatatag
    23521 ttctttaact aattgcttct cataatcagt caaatcgccc tccacaaact caacattaaa
    23581 ttgttcagct aatcccttta ctatgttttt ctgtagaata tctatgtcta tttttctgcc
    23641 aatttcattt tctattccac ttgctttttt agctgtaaat ttcatagctc tttctttcaa
    23701 ttctggtgtc ttagttttta ttaatttaaa caatttttct acatcaaaat ccagtattat
    23761 tgaaccatgt tgtaataaaa caccatcttt tctgctttga gcacttccaa ttaccttctt
    23821 attattaata gtaacttcat atgatgcatg tgcattaaaa catgcagctg ataaattttc
    23881 cctacttatt ctctcgcctc tatttaaatt atctgtttct ataccactta gattcaaccc
    23941 tttaactaga ccttcactta tatatctata agataggtta atgctcttat cgattaaagg
    24001 attatcttct cctataatta tactataggt tagctcatta tcatgtaata cagctcttcc
    24061 acctgtaatt cttctagtat agtctatatt catacatcta cacttatcta aatctatctc
    24121 atcttccaat ttctgaaaat atcctatact caaacaagct ggttcccatg tataaaatct
    24181 aagagttggc ttattatgtc ctttcttata tgcagtaaat atagcttcgt caattgccat
    24241 attcattgct ccttcatatg atttattatg tataactctc cactgattca tgattattac
    24301 gcccccattt ttagtataaa tatatcctag aaatcctcta tagatttatt tctcttattg
    24361 ctaaatctat ctcactttga tttaaaggtc ttgaatagtt gtatatagta cttcctggtc
    24421 tttcattata gtatggtcta ttacaatcct tacaacctct tatttcaaaa ggatagcctt
    24481 tgtttatgtc ttttaaaata tcattgtcaa gctttatact atttaagtat ccatttttaa
    24541 acttaaaata ctcttttgga taacctttat ttatcatata agacattaac tgtacccttc
    24601 tataactttc tatgcttggt tgacttatct tttccatttt agttcctcta actggagtaa
    24661 atgcaaataa actaatcgtt acatcatttt cctttaaata agtatataaa ttgtatatat
    24721 cttcatgact ttcacccata ccaactatta tatgtgtact tattttattg ggatatgatt
    24781 ttgacatttc agttataaat tttaactttt catcatagtt atttcctttt attttttcat
    24841 atagttcttt atttgctgca tctattgcta ttcctatttt atttactcct gctgaaaaaa
    24901 acttctttat ctgttcatca ttttctaatt ttgcagatag tgaaattggc atgtctatct
    24961 taccacttat atagtttata aagtctaaaa cagagttatg tgcttcttca cttgccattg
    25021 attgaataca tattctcttt atattttttc ctttataagc ttttaaagca tctaatattt
    25081 cttcttttga aaactctggc caaattactc ttgataattt atcttttcta gtactacttt
    25141 ctattgattg agaacaaaaa ctgcatttat ttatgcattt ttctccaatc attatatatg
    25201 ctgtggtagg aggtatatcg ctttttttgt ttaatatccc aagttctatt gctgtcccaa
    25261 ctgatagtct aatcataaaa cgcaacactc cttacactca tttattgtca tattcatttc
    25321 tatagcctta ttctttgcag accttgatgg taatactatt ctattgactc cacacattat
    25381 agataattgg tctagctctt ttctatacac tcctcttggt ctcatacaac ctagattaat
    25441 ttcagtatct ggtaaattaa ttctagcttc acataaaata tctgctaccc cttctaactc
    25501 aggaggttct acattttcat actcagtccc ttttgttgga ataaggacta taaatgtaag
    25561 cttattagga ggattttttt gtaggtattc tataatttca tattcaccct ttatttgtcc
    25621 tccttttaaa ccaatacata tatgtggtgc tacttctgta tgttcttgta ttgtattata
    25681 gacttcaata taatcttctt tactcttttt catcttataa acttctctta ttgtctcatc
    25741 atcaaacact aaatcaaaag aaactatatc taaatactta cacaactcta caatgctatc
    25801 tttatccata agacctaaat gagcattcaa tctatatcct tgctctttta agtttttaat
    25861 ggtattaata tgagtattta tagggacatc tccctcataa ctacaaccgc cactcaatag
    25921 aaagctagtt atattccttg attgtacttt ttcctcatat tcttctattg gcaccatatt
    25981 gtttaagtag tgaccgttgc aatgggcaca tttcaaacta cattgattgc ttgtagtact
    26041 aagagctagt gtctggttag gataagcaaa ctctatttta tttccaaaat tctttaattt
    26101 aatatcaaat gctattttca ttttttcaga tagattctta ttcatagttt attccttctt
    26161 aagtacattt tactcttcta gtaatttctt tgctgttggg aactgctcta tattcgtatg
    26221 tggtaagaaa catgcagaaa taaattcatc catataactt ggatatacac taagttcaac
    26281 ataagttatt tgattaccta tttcttcaag tttatttttt gcatctttac ttataagagc
    26341 taagtaagaa ccaacaagtg aactattccc tatataagta aatttttctc tatcgatatc
    26401 aggaagtaac cctataatta ttgagttttc tatgtctagg ttgtttccta taccacctgc
    26461 tatataaacc ctatctaata tactaaaatc catacctaaa ctatctacaa gagtgtatgc
    26521 gcctgaatat atagctcctt tagctctgat gaaattatct atatcaactt cattgactac
    26581 tatatcattt tctaaatcaa attcttcttt aaatgctaat acatactctc ctatctcatg
    26641 ctcattaaat ctaactctct tattatctaa atccctgtat attttacctc ttctatctat
    26701 tacaccttta gtaatcattt gacagattaa atcaattata ccagaaccac atataccaac
    26761 tggtgcacat tcatcaataa tctttaatgt tggctctaaa gtatctttat caataattac
    26821 tttctctatt gctcctgctg atgctctcat tccacagctt atccctccac cttcaaaagc
    26881 aggtcctgct gaacatgcac agctcatcat ataatcttta tttccaaata caatctctcc
    26941 attagttcct aaatctataa ataaaacatt ttcttcactt gaccatatcc ctgctgataa
    27001 tactcctgct gttatatctc ctcctacata acttgcaaca gatggagcta agtacacata
    27061 tgcactgtca tttacaaaaa gaccaacatt ttcacccata agttttggag attttaaaaa
    27121 tggtggtatg taaggttctt gtcttaagaa gtctgtatac acacccaaga ataaacttgt
    27181 catagttgta ttcccagcag ccactaatgt aactacatct tccttatcta ttccatttct
    27241 ttcatatatt gtttttaata gtggatttat agtttcctca actatagctt tatgaagtgt
    27301 ctctaatcca tttttcttag ttgaatatat aattctattt ataacatctg ctccatattt
    27361 tatctgtgca tttccagaag atgctttatc tactacctct tttgagtata ggtctactaa
    27421 acaaacaact actgaagttg taccaatatc tattgcaact ccgtataagg aattttcttt
    27481 atttccttgt tctatattta tgattgtaag tttcttttgt ttttgaacat atgttattgt
    27541 aaccttaaaa tcactctttc taaatacagt tggcattttt ctaagtatat ccaatctaaa
    27601 atctatttca ttatatccta ggttatttct aacatatctt tccaatctat ctacatcact
    27661 tatattatca tctaaatttg gttcttccat ttctatgtat ttctttttta tatttgtttt
    27721 aaattgaagg ttatgttctt caattatttt tttagctctt tcaaaaattt ccctatcctc
    27781 ttttttatta ctaccttcta tcttcatacc atgcatagag gatgatactt tagaaggaac
    27841 ttcaatttct atatctgata ttacctttgt acaacaagct agtatataac cttgctccca
    27901 ctcatcatct gttatatgtc ttgttttttc tgtatcaact tttccattca ataattttac
    27961 tttacacttc ccacaagaca cgtttccatt acaaggagca tctatgaata tatctgcatt
    28021 tcttgcaacc tctagtaata tatccccctc attacaataa acctctttat tgtttggtgt
    28081 aaaacttact tttatcatgt tatccctccc aatttgttct atatatgata aaaggaaagt
    28141 atagctaaat ttgcgtgcac tcaaatttta ctatactttc cccaattata ataatatctt
    28201 aatctttaat tattctaatc cagcctcgta ttctttatca cttaataacg tatcaagttc
    28261 agccacatca gctagtttta cttttaatat ccagttttca tatgggtctt catttataca
    28321 ttctggctca tcttctaatt tttcattaac ttccaatacc tcaccattaa caggagatat
    28381 taaatcagaa gctactttag aagactcaac tactccaaaa tctactccct tagttacagt
    28441 atcttctact tctggtgttt caacaaacaa tatttctcct aattgatctt gagcatagtc
    28501 tgttatacct atatatacaa catctccatc aattactttt acccactcat gatctttaga
    28561 gtattttaat tctggtaata atttcatttc gatagacccc caatattata ttattgatta
    28621 aattacttaa atcatattaa tattatatca tattatttta aattttccat caattacatt
    28681 acactttcca tagctaatgc tggatgacct ttttcttcta agaaagctaa tactccttca
    28741 gaatcgtcag ctatagtttc atcacaaacc atatcacaga agttttctat tccagtcatt
    28801 tctttaactg tagcatttaa tttatcagct acataatctt ttaattcttt tggcatccaa
    28861 actattcttt ctggtccacc ttctgcataa gcgaattttt tagaagatat gaaatgtctt
    28921 ccgtgtccca taaatcctgg agtttgaact cctccacctg tcatagaagc aagttctccg
    28981 aaagtcatac caactggagt aacacttgca aattctctgt taactacaac aaatccattt
    29041 gcttctggca ttataccaca gatacattcg aagcatccac aagaagtcat tgggtcttct
    29101 agtatagagt ataatgtaac agattcaact gcaccttgag atatttggtt tacagtttca
    29161 tttactgaat tccatacacc tgttctatca tctaagcact cgcctttttc tattggttga
    29221 caaggacctg ttgggtctaa ttctttagta gccttagcat ctaaccagct aactgctcca
    29281 caaagaccaa gtctttcagg agtaacaaca caaacgtgag ctggtgcaaa tgattgacat
    29341 aagttacaag aatagaaagt gtcaacactt tcatcaacta atgaagctaa tctttcatct
    29401 ctagcattgt acttagctat tgcttcacct tttaattcag aaactttttc agcatctgta
    29461 attatagtta tttcacactt atcaactact gattcaaatt catctaacat cttagcatat
    29521 aaaacttctc ctatatgctc aagtctaaat cctttatcaa atgcatcttt agagattctt
    29581 acccaagcca tatctctttg tccaacgtgc attacacctt ctatatagtt taagaagtag
    29641 tggaaacgtc tttcaagaac tggctcgaaa tcttcttgca tatttttacc agctatttta
    29701 actattacag caagtggtaa tcttaataca ccatctgcat caacttcatc tatatttggt
    29761 cctattattt ctatcttatg gtcttcaact tctgttgctt ctttcttaac aacaagctcc
    29821 caagcttcag ttctgtttcc accaaactca gcaaacatat cgctctttct aattctctca
    29881 ccttcaaatg ctgctgcaaa tgaaactggg ataggtattt cagtaacttt tatttttatt
    29941 cctctagctt ctaatgaagt agctactatc ttatcgtaat ctttttgagt taataggttc
    30001 attggaactt caagaactgt ttggtcagtt ataactggga atcctaaagc tattgctcca
    30061 gcacctgcag atacaactaa ttcacttaat ggtccaaatg cattaacaaa tgcaggaact
    30121 ctattagctg tgtactctaa taatccgttt aaatcaccag gagttaatcc accgaatatt
    30181 aatgctgctc ttactgcaac agatacaacg tgtataacag aagttacatc atatcctaga
    30241 ggtataactc ttagctcaag acccattttt actccagctt ctatagcttg gtctataact
    30301 ttaccaacta agaaagttag taaaccttta gattggtaat cttttataac ttttgctgct
    30361 gattctgcat ctggacactc accaagaaca actgcaacac caggtatatc tcctgtaact
    30421 aatggtacac caagtgatct gattataggg tcagttatat gacctgcaca tggctcacta
    30481 tatggagcat ccatagttga atattttaat gcttcaatta cttctgctgc taaagctgta
    30541 gctaaaccag cattaaaagc atgttctagt aaatgagttc tatttattaa agattttact
    30601 acttctaaag caccttctaa gtcccctaaa gtgttcatct tttgtcctgt tgcagcatat
    30661 atacaaggta atgaatatgc tgtatcaggg aaagcaactt tatgctcttt tccattcttt
    30721 tctatagctt cagctaacat agcttgagcc gcacctaaag cttgttctga ccctgtaaag
    30781 attatattat atagattcat tctatttccc cctttaatat ttacacctat tttttattaa
    30841 ctatacccta aaaaccctag aaagcaaatc caccttcatt taactctaag aaagagtctg
    30901 catataaaga tgccccgttg attatgtcac aagattttac agttttcatt aattctgggt
    30961 cacatggatt cattatagct gaactaaatc cattagccat tgccattgct aagaatgcac
    31021 tatctaaaac aggtctaaca tgcttaggac atccattaga tacgttagat aatcctcctg
    31081 tagttaaaag tcccatctca gtcatcattt ttatagcttc taaaacttct acttgttttt
    31141 cttgcatacc ttttataact aagcataatg ggtcaaatag tatatcagtt ggctccattc
    31201 ctaacattaa gcctttttct aatatttctt ggcagtaagc catacgctca tcattatctc
    31261 ttgggatacc ttcttttgca cataaaccta taaccattgc ttcgtattca gctgctatat
    31321 ctattaaatc aaatcttgag ccagcatcag cagagtttat tattggtttt gcattagttc
    31381 tatcataaac tttaagtcca gcttcgatag cttttttatt agctgtatct aatgctatag
    31441 gaacattgtt gaactcagat tgaagtaatt tgattcccca tgtcattatt tcttcgccat
    31501 ctctttcggc aggtcctata ttaaaatcta tatagtgtgc tcctgcttct aattgctctt
    31561 ttgctctttt taagattgga gctgggtctc tttctgctaa tgcttttctt attgaaggtg
    31621 atatacaatg tattctctca cctataatca taaatttttc catttataat gtcccccttt
    31681 aaatttaata ttaatagtta gttaatattt tattagtttg tttggcatgc tttttcttgg
    31741 tatcctttta agaacttagg taattccata gattcctctg gtcctataac tacattccat
    31801 cctggtaagt tatcttctat atcaccttta agtactgcaa cttttcctgg aatgataagg
    31861 tctttacaat tagttacttc ttctacctta ctttctttaa tgaaagcaga gattgagttt
    31921 ccaccaaatt taccagcagc ccaagatgta agaactgaat atccacctgc atctggtatt
    31981 actaaccata ctggaacttt tgatctttct atatcaccag caactatgaa gtaagttaat
    32041 gcaaagtcaa cagtaactaa tactggagaa ttttcatctg ggttgttgat tggataaatc
    32101 tttggttcaa ctctcattgg tctttgtggg tcagtgtata tgttttgtct tagtgcaaat
    32161 aatggtaatg ccttagcata actaatatca tctattacta ttatagaacc gtattttata
    32221 gtgaatattg atgataaagc aacttccatc ataggatttg aattagataa tctatttgca
    32281 aatactattg aaggatatcc aaatgttcta tcttgctctt ttaaagctgt tcttctaact
    32341 tgtatagcat tagtgtaagt atcttttatg ttttctcctg ttacatctaa tactaattct
    32401 ttatatccag cagcttgaat taattcaact gtttcatata attcttctaa gctaccagct
    32461 tttacaccta atggtaaact tgctccttta actacttcta tcatatcttt gtagttctct
    32521 ttagttgctc catataccat tggtctagca tcttttaata cttcaacagc ttctttaact
    32581 acttgtgcat catcacaagc taaaatataa gctacttcta atccactgcc ttttatttta
    32641 tctattaatt ttaaatacgc atctttatct ccacaatact ctaaaacagc catttcaact
    32701 ttcatttgtt caccaattct tacatagtca acttttttca tgttagctat tttagcatct
    32761 actgcttcat cactcataca agtacagaat gaaactgcat atctatttct acttactaat
    32821 gttttttcat gtctaaataa tactgtttct ccacctagtt catactcaga tgcaccagca
    32881 ccaactttta aagctttcat taaaggtgca gtagcctctg ataattttgc tatagcgtca
    32941 tcagacatat gtgggcattt acctacttct acagctcctg aagcaacctt catagagaaa
    33001 gccatacaag ttgggaatcc acaatcctta cagtttttct ttggtgttaa tttaaatata
    33061 tctaaagctt ttaatgccat tattttttcc ccctaacctt aacaatttaa ttaagctaat
    33121 gcgttaacca attcttttat agtttctatt gattttggat gacgaagtat aactgcgttt
    33181 gaaccaccta ctaaaacact tgctgcagtt gaaacttcca ttgctatagt tctttcttct
    33241 ggacaacccc aatctggctc atcttctatt ggagctatag cttctttaac atgacctact
    33301 tcaaaagcta ctggtgttat gataggcatt tgtaatgtct tatcattttg accaaatgct
    33361 gcaagtctaa ttctatccat agtagatgca acgtactcat atccataacc aactgctgaa
    33421 catccaacat tcataactat attttcacct ttaacgccta gttgagttaa caatacgttt
    33481 aattgtttag ctaggtttat atcaacagaa gattcagctc ctactttatg tgcataagcc
    33541 ataccagctg atgctcctac tcctttgtag ttgtcttcta ctgctgacat aaataagcag
    33601 ttatgtccat ccaatgtttg agctaatttt tcaaataatt taccatcttt ttcatgattt
    33661 cctgaaccag ctacaactaa aggtaatttt attgcttcaa ttactgcctt agctacatca
    33721 gcacattcat caactgactt atctaatcca tttgggtcag aaccatcaaa ttttaaacaa
    33781 ataaaatctg cttgtgtatt agcttcaaca tatttagccc actctactgg acaattagct
    33841 acatctttgt ataattcctt atatgaatca gtccagcttt caggataaac gtctgatatt
    33901 tgtataccta tttttggaga attacctact tctccatcaa aactataaaa aggtaataca
    33961 ttttccccac ctaatttaat tgctttttcc cctattccta cttcaacttc tgatattttt
    34021 ccagaatatt tttgagtaga cattttaaat gccatatttt tttccccctt aagcctattt
    34081 taattctaat ttagcaaaaa tttctttcat agccacttta gattttgaat cttcaggtaa
    34141 attaactaaa ggaatacctg tagaatcata ttcatatatc aattcatcca taggtacaac
    34201 accgattagc tctaggttat gcttttcaat ttcttcttta acaccatcat tcataacccc
    34261 atttggaact ttatttacaa tcaaaagtat tcttccaaca cttaacttta gttcctcagc
    34321 taaatctctt attctagcaa cagcttgtat gctacgtctt gagcaatcac taaccaataa
    34381 aagtgtatca acatgtctag tgacttttct acttagatgt tccataccag cttcgttgtc
    34441 catgactaag tatttgtaat gaccagatat tttgtttact tgttctctaa gtatcccatt
    34501 tacaaaacag taacatcctt caccttctga cctacccatt actaataagt catatccttc
    34561 gccttcttcg attatagaat ttaatctaaa ttgaagatat tgtgcctttg tcataccacc
    34621 agggaatgca ttgcctaact tttctctttg atttacttct tctcttattt ctcctattgt
    34681 tgcttcaact tcgataccta atacttcatt tatgttagca ttggcatcag catctacaac
    34741 taatactggt ccctttttgt ccttaaccaa ataatcaatc aaaagccctg tgagacttgt
    34801 tttaccagtt ccaccttttc ctgcaacagc tatattgtat cccattttaa gacttccccc
    34861 ttaaatctag ccacagagcc ttatgtactc tgtctgtcta ttataattta ggtacagaat
    34921 gaacacattc tccatgtaca tcatgaagtg cttccattag cccttcagat aaacttggat
    34981 gtggatgtat tgcatcccct acttgttcta ctgttaatcc tagatgaaca gcaagtgaca
    35041 actctgtcaa taaatctgta gcatgaggtc ctactactgc tgcacctatt atcttatcag
    35101 tttctttgtc agctataact tttacaaatc cttggaaatg tcctatagct tgtgcttttc
    35161 caagccctct aaaatcaaat tgacctacat tgtattctac accttcagct tcaagttgct
    35221 tctcagtctt accaacacca gcaacttcag gttcagtata aacacatctt ggaattgctc
    35281 tataatctac taccttagtc ttacctaaag cattttcaac tgctacgata ccttctttag
    35341 aagcaacatg tgctaggaaa ggagtatcta ttatatcgcc tattgcgtat ataccttcta
    35401 cattagtttc aagatgttca ttaactacta cttttcctct ttccatttca attcctatat
    35461 cttctactcc agaattgtca aggttaggtc ttctaccaac acatactaat gcatattgtg
    35521 cttctataac ctttccatta gaaagagttg caacagcctt accatcaact acttcacaag
    35581 tttgtactcc aatacctgta ataaccttaa ttttatcttt cttaaattgt ctaagtagtt
    35641 gtttagctac atctttgtct tcatttaata gtatttggtc aaccatctca actatagtta
    35701 cttctgttcc taaggctcta aagaactgcc ctatctcaca tcctataact ccaccaccta
    35761 ctattaacat agactcaggt atctcttcaa gtccaagaac ttcatcacta gttattacaa
    35821 cttttccatc atatgggaac attcttggta caactggaac agaaccattt gctagtatta
    35881 tcttatctgc ttttatagtt tctactgttc catcatcttt agttacttct atagtgtttt
    35941 tatcaattaa ttttccaaaa ccattaacta ggtttactcc tcttttttca aataagaact
    36001 ctataccact tattaattgg tttacaactt tattttttct ttccattatg gcagtgaagt
    36061 ttggcttaac tgtaccatct atttctatac caaaatcctt tgcttctttt acagtattca
    36121 atactcctga agaagcaaga agtgctttag ttggtataca tcctgcattt aagcaagttc
    36181 ctccaactct tcttttttca acaactgtta catctgcacc aagcatagaa gcttttatag
    36241 ctgctacata tcctcctggt ccaccaccta ctactactat cttcatcttt aattccccca
    36301 aacctaatat aatctacaat cttgcaatac tataaacctg cggcatccag tatagcaggt
    36361 atattctctt ctgccccaat tgccattata tgaacaccat cacataaatc ttcttctttt
    36421 aattgtttga taagttcccc tgccattttt attccttcac ttacccagtt ttcttttcca
    36481 gctgctctta atctttcgat ttgttcatct ggaacaaata ttcctggtac atttgcagtc
    36541 ataaatttag ccattcctgg tgattttaaa ggtactattc ctgctaatac cttgcaatcc
    36601 atatcccttg ttaattctct aaactttctc attgtattta tgtcataaag tgcttgtgtt
    36661 tggaaaaatt tagcccctgc ttttattttc tttttcattt ttaataattg aacttctatt
    36721 ggagaatatt ctggagttac tgatgctcct agataaaaat ctggagaacc ttttaactta
    36781 ttaccagcca tgtccgtacc tgccattaaa gtctcagcag tttgaagtat ccccacagaa
    36841 tctaaatcaa acactccctt agcttgtgga tggtctccta cgctagtatg gtctcctgtt
    36901 agtgccaaca gattgtttat cccaaataca cctgctgaca acatttctcc ttgtatagct
    36961 attctatttc tatctctccc tgttatttga ataactggct ctaatccagc atcttttaat
    37021 aatttacatg tagcaagaga agttgctctc ataactgccg attgaaagtc tgttacattt
    37081 gctgcatgaa ctcttccaac taacggcttt gcacattcta ttaaatgtga aaggtcagtc
    37141 ccttttggag gagccatttc agtagtaact gcaaattttc cactttctaa tgtttctctt
    37201 aataagctca tctctaatcc cccttttaac cttctaaaaa aaacttttat gaatttgctg
    37261 ctgcttcttt ctttttcttt gcacttaaac ttcttggatt attttgctta gaatagtctt
    37321 ttggtggtct tatttctgct aagttatcta attgtcctat agcttctagt ctttcatata
    37381 tctttatcca agcacaatca ttctctgagt ttacttcaca cttaccattt ttagctccac
    37441 cacaagcccc attcataaga cctttagcac acatagttac tggacatatc ccacctgtcc
    37501 aaccaagttc acagtctcca caagccttac aggcttcttc atattctcca actctttgta
    37561 cttcccctat aaacaaagta ttgttggctg gataaactgg cttatctttt aaattcttaa
    37621 ctattgtctg tgtaccatct ccacatgcta aagataaaac tgcatcagct tccttagtct
    37681 cttcttttag agcctttaaa tcctttttag actttaaaag gttacaagca gggtcaagca
    37741 ttacatatcc taagattttt ttgccttcac cttcaagagt ttccttcatt tttaaaactt
    37801 cttcttcccc accactttta caagttgctg cacattgatt acaaccaact aaaaccagct
    37861 tgtcaaaatc ctttaagtac cctagcactt cttctaatgg tttattttca gaaattatca
    37921 tatctacttc ccccctaaac cttccacata tatatctatt tattgttttg taatttacaa
    37981 gccttaacta catgttttgc aagtatagat gttgtaactg aaccaacccc cgctggaact
    38041 ggagttatca ttgatacttt gtctaaaact gcatttgtat caacatctcc acataaattt
    38101 ccttcttcat caacatttat accaacgtct ataactaccg ctccatcttt aacaaaactt
    38161 tcatcaacca tcttagctct accaatagct gctattagca cgtctgcctc tgctgctaca
    38221 cctgatagat ttttagtttt tgaatgacat attgtaacag ttgcatgttc acttaataaa
    38281 agcattgata ctggctttcc aactaccatt gatcttccaa gaactgttac cttacttcct
    38341 tttaaatcaa cattatagtg ttttaatatc tcaactactg ctgtaggtgt acatggtgga
    38401 aatccacttt tatccccttc cattacctta gcagagttta ttggactaaa acaatctacg
    38461 tctttttccg gtgcaataac atattttata acttcttcat ttaagtgttt tggaagaggt
    38521 ctaaaacata atataccatt aacatttttg tcatcattaa ctctctttaa tacatcaata
    38581 tattcctctt gtgttatatc ctcagctaac tctaacactt ctgttgttat acctatgttt
    38641 tgacatctct ttagtgctcc tctttcataa gataaatcat cacttcttgc cccaactcta
    38701 actattgtta gtttaggatt tataccttct ttaactagta aatcgacttc ttttattaat
    38761 tcttcactaa tcttatcagc tacaggtttt ccttttataa tttgtccttt agttgacatt
    38821 ccttccatac attcacaact cccctacaag caaacttaaa ttaatttatt ctatatacca
    38881 catattaata acatagtatc tactttcgtc atttaaaaat tattttccaa gagctttttc
    38941 aactttggca taaacttcat cacaaatttt tacaccatct tcaactaact tatctacttc
    39001 tgtttttacc ttattaacat attctttatc ttgtatagaa tttatattta taactacatt
    39061 taattgtcca ccaagtatag cagctcttaa acactgaact cctacaccaa catcacttat
    39121 agcaagtctt gaacctttat caactaaatc ttcatgtaac ttaatagctt catagcaaac
    39181 tcttactatg tttaatggta cttcacaagc aacttttaat gccttttcca ttgtttctgc
    39241 ttttattctt ttttcttctt ctgtttcttt aggaagcccg taagcttttg ataatggtaa
    39301 gaaacattct gcatcatcat ctatcatttt taataaatct ttttctaact ttcctgcctt
    39361 acttaatatc tcttttacac tttcttcata ctcagcatac ttcttcttcc ctattgtaag
    39421 gttacatacc atactaccta aagccatacc tattgcacct actagtgcag cagctccccc
    39481 accacctggt actgcttctt tggaagatag tacttctaca aaatcaacac aagttttatc
    39541 tgctattttc atgataatcc tccttgaaag gatgtaggaa aatatctcaa attgttcgag
    39601 atattttacg aactatttta agatatctcc tactctttat ttataaatta atttccttag
    39661 aataatccag ctattactcc attttcatca acatctattt tttctgctgc tggaactttt
    39721 ggtaatcctg gcatcttcat tatttctcca gtaagtgcaa ctataaatcc agctcctgct
    39781 gaaattgttg cttgtcttac agttattcta aatcctgttg gtctacctaa tttagtttgg
    39841 tcatcagtta aagaatattg agtcttagcc atacatactg gaactttagt aaatccaagt
    39901 ttttctaagt tagctatttc cttatcagct tcaggagtat aatctacacc atctgctcca
    39961 taaatcttag tagctatagc atttatcttg tcttttatag ataaatcatc ttcatagcag
    40021 aatctaaagt tattttcttc ttcatccaat aatcttaaaa cttctttagc tactgcaatt
    40081 ccaccttctc caccttttgc ccatacttca gaaagagcaa cattaacacc taattcctta
    40141 cacttgtctt caacaagttt aagttcagct tcagtatcaa gtgggaatct attgattgca
    40201 acaactgctg gtaatccata tacttgagtt atgttttcaa catgttttaa taagtttgga
    40261 agtccttttt caagagcttc taggttttcg ttatttaagt ctgctttagc aactccacca
    40321 ttgtatttta atgctcttac agtagcaact attataacag catctggttt taagtttgcc
    40381 attctacatt ttatatctaa gaatttttct gctccaaggt cagcaccgaa accagcctca
    40441 gttattacat aatctgcaaa gtgcatagcc attcttgtag ctataacaga gttacatcca
    40501 tgagctatat ttgcgaatgg tccaccgtgt acaaatgatg gtgttccttc aagagtttga
    40561 actaggtttg gttttaaagc atcttttaat aatgcagcca tagcaccatt agcttttaat
    40621 tgtctagctg ttacaggttc accttcgtag ctgtatccaa ctattatgtt tcctaatctt
    40681 tcttttaaat cagatatatc acttgccaaa cagaatgctg ccattatttc agaagcaaca
    40741 gttatatcga atccatcttg tctaactgct ccatcacctt ttttacccat accatcaacg
    40801 atatttctaa gttgtctatc gttcatgtct acacatcttc tccaagttat tttcttaggg
    40861 tctattctaa gtgcatttcc ttggtgaata tggttatcaa gcatagcagc taaaagattg
    40921 ttagcagctc ctatagcgtg aaaatctcct gtgaagtgta agtttatatc ttccatagga
    40981 acaacttgtg catatcctcc accagctgct ccacctttaa caccaaatac tggtcctaga
    41041 gatggttctc ttaaagcaac taatacattt ttgtctagtt tagcaaatgc atcagcaaca
    41101 cctatagtag tagtagtttt tccttcacct gctggagttg ggtttatagc tgtagttagt
    41161 attaacttag cttttttacc agtctctctt tttagtagat tgtagtcaac ttttgctttg
    41221 tatttaccat aaagttctac atcatcttca cctagtccta atttttttgc aacctctcta
    41281 atatcttgag gcttagcttc ttgagctatt tcaatgtcag atttaaatcc cataactgaa
    41341 tctcctccca caacctaaat agatttaaaa tataattttt gtaaaaattg tattaatatg
    41401 taaaaattat attttataag ataattatac atgtaaaatt acttaaaaac tagctactaa
    41461 gctattaaaa tattcaaact taatagctag ttatttatct aattacttac ttattaccta
    41521 tctattgcct atgtctaacc tttaaccaac ttaaaatccc aaatcaaaat ttctatctat
    41581 tttatttatc cttaagtgac attaatttat cttttattgc tttaatctgt tctttcgttg
    41641 tttcactaga atcatatgga gattgattag ctctatcaga atcaataaca tcttggttat
    41701 aataaataaa tcctaaagat tctccatctt ctaagttttg gattataaat tcttcatctt
    41761 ccttatttct aattttattt cctactacaa atactttatt tacacctata tcatgtccaa
    41821 gtttcttaac ttttctataa gtctgtagac ttctctctcc tggttctaca actactataa
    41881 aagcatctac accttgggct gttcctcttc ctaagtgttc aattcccgct tccatatcca
    41941 taaccactac atctttattt tgtagtatta aatgtgagca gagtctcttc aaaagaacat
    42001 gctctggaca tacacatcca gtaccaccag aatctacggt tcccaatgta agtaatctta
    42061 ctccattgta ttctttacag aaattttcag ggatatcgtc tactttagga ttcatcttaa
    42121 acatttttcc aaatgaacct acagaagcag ctgttctatc tgaaactaat tttttcattt
    42181 ctgatatagg tactattgat tcatatactt cttttggaaa acctagtgct aaagctaaat
    42241 tagcatcagg gtcggcatca acagcaacaa ctctgtatcc gtcttcagca aacatcctag
    42301 agagcattga agaaaaagtc gttttaccta ctccaccttt acctgttatt gctatcttca
    42361 taatccctac caccttttat tactatttgc tttttagtag ttaattttac agttaaatat
    42421 tttttatact ctatattttt atacactaaa aataaactac agctagtcct tacaggaacc
    42481 aattaaattt accctactag cttttcaaag cagcatgtat agttttatta ttctttaata
    42541 ttgtttatat tttatttatt cagtatattc attatatttt gatgttcttt actttaatat
    42601 ttgactttat tcaactttat tcaaccagaa acttcttata aaaacgttta ttctataact
    42661 tcactatttt ttaagcttca gccttttctg tcattttttc ttcaactaat gcttcaaagt
    42721 gaacacgttt tttctctata tcttctatta ttgtagctgc taactctttt ggatttgtat
    42781 ttacagtaaa tgtagctcca actttatctt ttaattcact agttaatata tccactgctc
    42841 ttgaagaacc agctattgga ggcattattc ctaaataagt gtctatacca gaagctacaa
    42901 catagcatcc tatagcaact gctttttctg acatccactc tggagctata cctacaactg
    42961 gaaggtcaca catatccata tctaagtaat tagctgctgc tccaactaaa tctagtatac
    43021 ggcttatatc aacacaagaa cccatatgta gtactggtgg gattcctact aatttacaga
    43081 cagttgcaag acctttacct gcatattttt cagccgcatc agattccatt aaaccaaact
    43141 tagctgctgc tgaagctcca caacctgtag taactactat tatgtcgttt ttgattaatt
    43201 ctttcattat tgttacgtga gcctcatttg aaactccttt agcattgtta catccaacta
    43261 caccagctgc tcctcttaat actccagctt ttagacagtc tgttaatggc ttaactgttc
    43321 ctgctgggtc tatatgagag tttacaactc tgtctaattg atttactact gcttctacac
    43381 tatacccaac tgttgcccct gattttaatt caggtataag tacttttgat ttatctctat
    43441 ttttaaagtt taaaatagct tctttaacta ttgctttagc atcatcaagt gcttgttctt
    43501 ctctaaattc aatataagtt gaacctgtta tcttagcttt tggagaagtt gttacaaatt
    43561 tagtatggta acaatctgca actctagcta atgcagggaa tatacattga acgtcaacta
    43621 ttacagcttc aactgctcca gttattattg caagttcttg ttgatggaag tctcctgcta
    43681 tttttacacc atgtctcatt gtaatctcat tacctgtaca acacatacct gctaagttta
    43741 ttccatcagc accaacttct ttagctaaag ctactaagtc tggctcttct gatgctaaaa
    43801 ctatcatttc tgataatgct ggctcatgtc catgtaatat tatgttaact ttattttctt
    43861 ctaatactgc taaattcgcc tctgttcttc ttggcactgg agttccaaat aagatatcgc
    43921 ttagacgagt acctatcata gaaccacccc aaccatcagc catagaagtt ctaagactca
    43981 tgtgtattaa actatctata tcaccagtac atcctatatg agtagagtgc attattgttg
    44041 caatttctct atctatagct cttggctcta tagcgtattc tttccatatt ttttgtcttg
    44101 gttctggtgc attttttata aatcttaatg tcccaaaagg ttttccaaat tccattaatg
    44161 caatttctgc cacttcatgt gctacatcat agatatctct accttctgtc tctacatccc
    44221 attctttagc taaagtaatt aacttagctt cgtctcttat tttatagttt ccatttggat
    44281 cagctaatgc taatgtatgt gctatatctc tagcatggtc tgaatgggca gctgtcccac
    44341 cagcaaccat tcttgcaaag tttctaccta ctatagtatg ctcatctgct ccacataacc
    44401 cccttggagt cttagggctt attctacatg gtcccattcc acatattcta cagcaaacac
    44461 cttgaagacc aaaaccacat tgtgccttaa agccttcttt tctatcatac attgtttcta
    44521 cgccttcttc tctagcttta gctatcatct tctggctgtt taaatcaatt gttaacattt
    44581 tttcatccat attcctatcc cctttttttg atttttaaaa tcccccaggt gactgacttc
    44641 atgtcataaa ataataaaat aaatgctttc taagttgatt atatactaat tttcagtgct
    44701 ttgctttaga tttaaatatt tttttaacaa aattagataa tacataaaaa ttttattttc
    44761 tacacttaat ttaagttgat tttatcgctt gtttttggct atttgttaat atctaaacct
    44821 acttttttga tacttcagtt taattaaatt atgttttgat ttttttaaat caaatttgaa
    44881 atttttctag tcatttttat attattgcag attgtttgtg tatttattat ctttcactac
    44941 tgtttggact tattacagat ttttactccc taaacttaat tagtaaaaac ttcttagaat
    45001 agcatttttt ggactaattt ttttgaattt ttttattttt cctactttaa tattaattat
    45061 agcttcaaat tgaacatttg tatatattca tttgaagcta taattatttt ttatataaaa
    45121 cttttttaat acagcattaa tttagacatt ttgactattt tttctacttt aattcattta
    45181 tttcaagcga tttatcctat ttcatatttt tagctacaat agccccatat gcaatagaat
    45241 ataatttaga ttcatgtgaa tcagctcttg acactaaaac tataggagct tttgcaccca
    45301 taattatacc tgctgattta gagtctgcca tatatgtaaa ggctttccct attccattac
    45361 caacctctat tgttggaacc aatatgatat ctacatctcc agatacttca cttttaaacc
    45421 cttttatctc actagcttct tttgaaacag ctaaatcaaa agccagagga ccttctacaa
    45481 ttacattttc accaaattct ccttctttac aagcttttgc taacatatct gcatctacag
    45541 ttgcttgcat cttaggattt actttctctt tagctgccaa acatgcaact tttacagttt
    45601 ccattcctaa agcttttgca gcttttatag aattttttaa tatctttgcc ttttgttcat
    45661 aatcaggagc tatattcata cctccatctg tagttataag taatttatgg tatttttcta
    45721 actcatatac cataacatga cttaataaac tatcagttct aagaccatag tctttattta
    45781 acacttcttt taatatgaca gatgtatcta ataatccttt cattacaaag tcagcttctt
    45841 tacttgatac taatttaact gctatttctg cacactcttt gatatcatcc ttatccacta
    45901 ttttgatacc acttaaatca aatcctattt cttttgatat ttctcttatt ttgccttcat
    45961 ttccaaccaa tataggagta attatatttc tttctacagc atcctttatt gccattaaaa
    46021 cttctttatc atgagctgct gctacagaga gtacaatttt ctctcctccc ttaagttgtt
    46081 ctaaaatatc atctaatttt tttatcaaaa gtaacccctc ccttatatat atttaactaa
    46141 ataataccat atttgctata ccttttctca atttattttt tatgttataa agaatttata
    46201 taactaaaag acagtttaat attttattct gggatttcat caataactct taaaagcttt
    46261 gcaggaacac cacctacaat agtattttct gcaacatttt ttgttacaac tgctccagca
    46321 gcgataatta cattatctcc aatagtaact cctggaacta tagttacatt agcaccaatc
    46381 catacatttt ttcctattgt gattggagaa ggataagttg taccacgttt ctctggtgca
    46441 ataccatggt taagtgtagc caataccaca ttatgcccaa tttgcgtatt atctccaata
    46501 tcaatccccc cctggtcttg aaaatggcaa ctgctattta taaaaacatt ttttcctatt
    46561 gtgatgtttt ttccacaatc tgtataaaat ggtggaaaca taaaaaatga ttcatctacc
    46621 ttttttccaa ttaactcaga aaataaacta cggacttctt ctggttcatg ataagaagaa
    46681 tttaacttac ttgtgatttt cattgcttca ttactcaact taaccataaa ttcatgtatt
    46741 tctgatttac tagaaacagg ttttctttga ttgatatgtg ttaaaaattc attgatattc
    46801 attttataca tcctttcaat atgtgcttta atttatttgt acattctaaa taatatttta
    46861 ataaaaatta atttaattta tttttattaa aatatcattg cttcttttag tgtaatatac
    46921 aattatatct atatcaaata tctatattaa atacttaact atacttaaaa agcatataaa
    46981 ttgatataat tatataatag ataagttaat attgaggagg gataattatg gaaataagag
    47041 tattaagata ttttttagca attgcaagag aagaaagtat atctggtgcg gcaacctttt
    47101 tacatataac acaaccaact ctttctagac aaattatgga acttgaagaa gagttgggag
    47161 ttaaattatt ggttcgagga aatagaaaaa tcaccttaac aaatgaaggt aggcttttac
    47221 ataaaagagc agaagaaatt atatcattag ttgataaggt tgaattagaa tttgacaatc
    47281 ccaatgagat tattagcggt gatatatata taggaagtgg tgaaactgaa gctatgcgac
    47341 ttatagctag aactgcccat cattttcatc aaaaataccc caatgtaaga tatcaccttt
    47401 ttagtgggaa tgctgatgat gtgactgaaa aattagacaa gggactgctt gattttggta
    47461 ttttaattga acctgcaaat atacagaagt atgattatgc acaaattcct gctactgatg
    47521 tatgggggtt actaatgcgt aaagatagtg cccttgcatc acaaagcaca ataaatccaa
    47581 aagatttatg caatatacct cttattattt caagacagac acttgttgat aaagcaattt
    47641 ctaaatggct tcaagacagt aatgaaaaac taaacattat tgcaacatac aatttagttt
    47701 ataacgcttc tcttttggta gaagaaggtc tgggctacgc tctgtgttta gatagactcg
    47761 tcaatactac agaaaacagt aatctttgtt ttagacctct atctcctcct ttagaagcta
    47821 aattaaatat tatatggaaa aaacatcaaa tattttcaaa ggcagcagaa aaatttttac
    47881 ttcaaataca aaaagatttt tcttctatca tgttggatac atctaagttg gatacaccta
    47941 aagaaaaata aatcataata aaaagtgaga gtgtctcaaa atgaactttg cactgtataa
    48001 ggcactcttt tttatacaaa gtaaaatata tgttcatcat ttcagcacta aaaaagaggc
    48061 ttatctctat tttgagatag ccccacttaa ccaataaaat taaatacaac ttaacaatat
    48121 ccttacttat ttattccaag ttctcttaga caagcaatag taatttcatc ttgtggattt
    48181 aattcataag ctctttctat atagtaagtt gcatcatcaa tatcaccatt atttaaataa
    48241 gccattccta aattgcaaag tatttctggg tcttccttta tcttagccgc ttgttcaaaa
    48301 tactctattg ctttatctaa attattctta taagcctcac aaagccccaa ttccactata
    48361 gtatccactt gattaggctt tattatcaat atcttctcaa gatacatctt agcctgctct
    48421 atttcgccca tacccttata tccaagtgct atcataaaca gcaagttcca ccaatccata
    48481 tgttcttctt ctaatggaag taacttctct aatccttcct taaacttacc ttggaataca
    48541 agtgtatatc cttcttcata ttgaacttta aagtccatct tgcccagatt ctcttgtacc
    48601 tcagctacta aatcagcatc taaccctagc cttaacgctt cttcccaagt cagcttagtc
    48661 tttaaatatt gaccttgatt ataataatgg tagcctaagt gataataacc taatgcaaaa
    48721 ttctcatcaa catcaattac cttttcaagc ttagccatgg cttcaagtaa gaatgcattc
    48781 attgccttat catccatatc tttttgatac tgtttagcta tctcttggca aacaatcgca
    48841 tagttataca ttgcatctaa atcatctgga tacattgtta taaatgcttt tatatatatt
    48901 aaagaatctg tatgttcacc aatctcaaag tattttctcg acatatatcc catatacgat
    48961 ttcaaatcca aatcaatatc ttttgataaa gcatttaaaa acttctcata ctctgcattg
    49021 tttttaaact tactatctat tccaattata tatatcattg catctgctat agacattgaa
    49081 tttaacttat cttgagcagt cttttctttt atccctttta ctaatacctc attttttata
    49141 ggtacatcta atccaccttt tggcacttca tagcttttta atttaaactc tccaccatgt
    49201 tttatagtta taaaagctaa ttcttctgtt ttttttagca aatatttttc tatcttaaaa
    49261 tccattttat cctcctaaat acttaaatct ctactttatg agttttagat ttctcaaata
    49321 tttttttatc atcatactca aataagacta cattttctac ttctcttatt tctgtattta
    49381 tatcattttt taaatccaca acattaaatc taaatggctc aaaatgaaca tattttatta
    49441 tatgtttagc tggtttatca acaaaactag gtaaatatgt tgataagtta tcattatctt
    49501 gtaaaaatac atggcatcta ttcttaaaat catccacatc tagcttatta aaaaactgtg
    49561 gtatatttga tgttttaccc agtgatatat agtcatattt taatatatcg ttgaatacat
    49621 cattatctat gttgattttt tcattataga aatccatcaa tattttatat aactgattct
    49681 ttccttgtgc caaatcaaag tagccatttt catcaaaata cttggcaaaa acctcaaaga
    49741 atttaaaagg gcttttttta taaaatctgc ctataatata tctcatagat aacacaaagt
    49801 ttttagaatt gtagtatctc tccagtatat cttctatatc ctttagcttc aaagtttctt
    49861 catagcttat ataattattg tataaaaact catatggagc ataatcctta tatttaaaac
    49921 catgctcatc tgcaactttt ctcatacctg tccctttaat catctttaaa aagcctaatt
    49981 gcaaatgctc tatacctaga ttaaatacat cattaaaaga attttcaaag ctcttataat
    50041 cttcataagg cagtcctgca attaagtcta agtgctgatg tatatttcta taagatgcta
    50101 cagtttgtac aacatgagac aactttttaa aatcatccct tctacctact gcatcaagtg
    50161 ttttttcatt cgttgactga acacctattt caaattgaaa aagaccttct ttacaatcag
    50221 ccaaaaactc aagcatctta tcatctatca aatacgctgt aacttcaaaa tgataagttg
    50281 tatatccatt atcatttttc ataaggaaat ccatgatttc catagccact tttctatttg
    50341 cattgaatgt cctatctata aactttattt gtgatactct tgcatctatt aaagctttta
    50401 aatcactctt tatcctgtct aaactaaaat accttagacc tggaatagta gatgataaac
    50461 agtattggca gttaaaaggg caacctcttg atgattcata atacactatt ctattttcat
    50521 attcttttgg attcaagttt tcataaggac taggaatctc atccaaattt tgaagtaatt
    50581 ccataggctt attcactatt atctcattgc cttgtctata tacaagtcca tttacatcat
    50641 ttatttccat ctttccttgc aagtgaagta ctaagtctct aaaaattaat tctccctctc
    50701 cataaagtat ataatccaca aaatcatact ttttcattgc ctcataacta tcataactca
    50761 cttccggtcc gcccaaagct attttagtat taggtctaat tttttttaga ttatcacaaa
    50821 gtttaactat atctcccaca ttccagatat atgttgagaa taatattata tcatattcat
    50881 ttttatatat atcctttaaa atatagtcca aatcgttgtt tatcgtgtat tctttcatat
    50941 taacttctat caaatctctt acaaattctt ttagatatct tatagccaaa tttgtatgaa
    51001 taaacttgga atttaatgtt gttaataaaa ttttcaaata tttctcacct ctttttaaga
    51061 ttatactgtc tttttgtacc ccttataggt taaaatagta tatgtaaagt ctaaataata
    51121 tctatataat taatttatta atttcaagta atgtgaggaa aggaagtttt ttatggaatt
    51181 aattgaaaaa gtatctatca actctttatc aaaaagagat ttactactta ttataaagtc
    51241 tcttgaatac actaatgaaa atactcaaat tagtgatttc attgacctta ggaataatat
    51301 agtaaaggaa ttatgttttt taactgacac taaggaaaaa gattttttag attatctaga
    51361 aaaaaatagc acactctaat aacctaaacc tttttaaact ttaatatata aatacctgat
    51421 ttagaattta tttttatgct taatatatta tcattaaagg ttttcgacat aactgttatt
    51481 tgattaaata tagggtctat tatagtatta ccttcttcaa gtcttataag acttcttggg
    51541 tctatgcttt tattatatgc cttaactcca attttatatt ttctcaattt aacaacatat
    51601 tcggacatag aaaaaataaa atctatatta tcttcattta atttactatc ttcacccaaa
    51661 atggataata tagatttttt tatgctatta attccttcat tttctacaat tctatcttcc
    51721 atatatacat catatagaac atttaaaaca tttaataaaa tactttcttc atcataatct
    51781 tcagatttca aatcaatgta cttatcaatt aattgtattg ctttaatcct tgccatctga
    51841 aactttacaa catctgattt gtctaattct atagaaaatc ctattatctt gtctttaata
    51901 ctctgtagta attcgacata ctctatttta ctattattta taagattgtg cataatggaa
    51961 ttatacacca cagaacctaa taaataatca aataaaagtt cttctttttt aaaataaata
    52021 acatactttt ttattagttt aataacctca tcttcacttt tttgaatatt agtatttgat
    52081 aaaattagtg gtaataaaat atttaaaaaa ttgatatttc ctattttttc tccataaaat
    52141 ctatagtaaa taagttcatc tctcagtcta ttttcgtcta tatacacaca tctttgtgtt
    52201 ttatcatcta ttaaggattt tgtatttatt atagttaaat ctttaagagc cctacttgca
    52261 ctactaaaag aagatgtgta gacttttttt agtaattcgt cattcataaa tatatccttt
    52321 ctgaaaaatt gaatgtaaat aaattgttat taaaaaaaaa agagacagcc cgtttaagaa
    52381 gctgtcatat atagggggat agtagtgtac aaaaatcatt gtaatctact atctatatat
    52441 tattatacga tactactttt ttatatgtaa agcatcagtt ttcgacatcc ctatatttta
    52501 cagttataca aattgcgtac taagttcaat tttattcttt ttatttcaac attttatcat
    52561 gctacattct ttcaggagcg tgcattccca acaatttcag agaattttct aaagtttgtt
    52621 ttgttgctaa aactaatgca agtcttgctt ttcttatttc caaattttct actaaaattg
    52681 gattgtcatg ataaaattta ttaaacgctt gagctaaatc tagcataaat ctagtcacta
    52741 tatgtggctc atttttcttt agagcaagta aaatattctt attgaatgat tctataactc
    52801 taagaacttc tgcactatct tcatcagcta atagactata atctatatca gaagtcactt
    52861 ctacttctgc ttttcttaaa actgcacagc atctagcatg tgtatactga acatatggtc
    52921 cagtctcacc atcaaaacta agcgttcttt cccaagagaa ggtatagtct ttaattctac
    52981 tattagataa ctcttggaat actactgccc caacacctac ttgcttagat atttcatcca
    53041 catttttagc atttgggttt ttagctagta taatttcctt agttttatct atagcttgat
    53101 ttaaagcatc ttctaaaaat actactcttc cttttctagt cgacatagta ccttcttcaa
    53161 gtgcaaccat accaaatcca acatgaatta aatcttttgc ccaatcatat cccataagct
    53221 caattacctt aaaccattgt tggaaatgta agttttgttg agaaccaact acatatatac
    53281 acttgtcaaa atcataagtt tcttttctat atattgcagc agctaaatct cttgtcatat
    53341 ataacgttga accatcattc ttagtaataa gtgctggtgg cattttatac tcttctaaat
    53401 caacaattct tgctccttta gactctttta aaagattttt ctcttctaat agttcgataa
    53461 ccctgttcat tttatcagaa taaaaactct ctcctgctaa agaatcaaat tctatatcta
    53521 aaagtttata aactctgtta aactctttta aactctcatt tctaaaccat tgccataatt
    53581 cttgtgcttc ttcgtcacca ttttctaatt tattaaacca tgctcttgct tcatcttcca
    53641 tttctgggtg ttgttcagct tcatcatgga atcttacgta taattttagc aattctggaa
    53701 ttggattaga ctctactact tctttttctc cccacttttt aaaggccact attaacttac
    53761 caaactgagt tccatagtca cctaaatgat ttattcttat agtcttgtat ccttgcgaat
    53821 catatatctt atataaagca ttacctataa ctgtagttct tatgtgccct atatggaaag
    53881 gttttgctat atttggagaa gaatattcaa ctattacagt tttatctttt ccaaaatcac
    53941 tatgtccgta attttctttt tcatctaaaa cttttttaat tacagtttct gctaattgag
    54001 atttatttac aaagaaattt acatatccgc ctaattgtat tacttttgtt atctctccac
    54061 ttggttctat actttccgcc aattcacttg ctatcatgtt tggagctttt ctaaacactt
    54121 tggctaattt aaagcatgga aaagcatagt cccccatatc cttatttggt ggaacttcta
    54181 taagtgcctc tatctcttct ttcgataaat cttctatttt ttctttaagg caatttgata
    54241 ttgccacctt aaaatcttgc attctgttgc tcctctctac attgttcctg gtttatattg
    54301 tgcttatctc tttatgttaa atcaaatttc gtgttttttc aagtatttca ttacagtgta
    54361 aaacacttta gtaattatgt tttctgtata tattaaaaat actataattg cagtttttaa
    54421 tcacactatt attgattttt tataagactt ttttctattt tattgtttct tgtactatcc
    54481 agttgacttt atatactttt tttaatcttt tatctatttt catacgtcaa tgctaatttt
    54541 atatactttt cttttaatct tttattaatt ttcatacatc aatgttaact ttatatacgt
    54601 ttttttaatc ttttatctat tttcatacat caatgtcagc tttatatact ttttttactc
    54661 ttttatctat tttctataaa tcaatattag ctttatatac tttttttact cttttatcta
    54721 ttttctataa atctttttca ctcttaactt ttattccttc ttcttctaat agccttgctg
    54781 ttataccttt ccctggtatc tttttacctg aaaaactacc atcatatatt agattacatc
    54841 cacaagaggg gctaccctct tttagtattg cttcgctaca tacatataaa tttgctattt
    54901 ttagagtttc attagcccct cttacaaagt tttctgttac atccttatta tctttagtaa
    54961 ttacttttcc atcaactatc tcagcaggtg gtcttggtgt agatagacca cctaactgct
    55021 ctgggcatac aagtgtaaat tctttgcctt ttaaatattc cttgactttt tcattatcat
    55081 tattatcgcc actatattta caatttattc ctattaaaca tgcagatacc aatatcataa
    55141 aaatgtgctc ctatacaaat tatatatatt ctcatacaaa ttactaatgt attcttatac
    55201 aaattatttt aatttaacaa ttgttactcc tgctccacct tctccatatt gaccacctct
    55261 ttgtgatttt acatgtctat ttcttcttaa aatgtcttgt agccctgctt ttaatactcc
    55321 tgtacctatt ccatgtatta ctgttacaga ctctaaacct gccacatatg catcatcaag
    55381 atacttttct acttccatta tagcttcttc taggtttaac cctctaaggt caacttcatt
    55441 ttttacacta ccagattttg accttataat gtttctcgtt gatttagtta catttgttga
    55501 aacatctttg cgtgtttttt gtaaagattt aaaaggtaga gtcatcttca ttataccaat
    55561 ttgcactact gcttcttttc tctttttatc tactgaaact acactaccat tttgatttaa
    55621 agttattacc ttaacttctt cacctggctt taagtctttt atctccttat ttgatacctt
    55681 tggaactatc atacttttta ctgttggctg aagacttccc atagagctag tcaattcttt
    55741 tctaagttct tctatcttac gattcttttc ttttgaagct ctttcttgtt caagacttct
    55801 aagttctttt attataatat ctacttcttc tttagcttgt cttataattg aaaatgcttc
    55861 tgatttagct ttttcaatca tcttatctct ttgactgacc aatttttcaa gtttttcgtc
    55921 atactctact ttcagttttt caatctcttc ttttaatctt tcagcttctt ctctatcttc
    55981 tactgctttg attctattct tttcaacatt ctgtaacaca tcttctaaag ctatgttttc
    56041 tgtatttata tattctttag cacgtgaaat cacataatca cttagcccaa gttttctaga
    56101 aatctcaaac gcatttgatt ttccgggaac acctataagt aacttatatg ttgggcttaa
    56161 agtttctata tcaaattcaa ctgctgcatt ttctacacct gatttagtaa gagcataatt
    56221 tttaagctca ctatagtgag tggtagctat acatttagct cctacagaat ttatatcttc
    56281 taatactgct attgcaaggg cagctccttc aacagggtct gttcccgctc ctaactcgtc
    56341 aaatataact aaagagtctg ctgttacgtt ttgtaatata gatactatat tcgtcatatg
    56401 agatgaaaat gttgatagac tctgttcaat actctgctca tctcctatat ctgcaaatac
    56461 attatcatat acacacatac tacttccata atcagcaggt atatgaagtc cactttgtgt
    56521 cataagtgca aatagaccta cagtttttat tgtaacagtc ttaccacctg tgtttggacc
    56581 tgttatcacc aatgtatgga agtctcttcc taaataaatt gtatttgcta ctaccttctt
    56641 tttatccagc agtggatgtc ttccattttt tatgtttaaa tatttatcct catttaaagt
    56701 tggttctatt cctctcatct gtatagaaag ttttcccttt gaaaatgcaa agtccaatct
    56761 tccaagtatc tcttgattag aaattaagtc ttcactaact tctccaacca tagcagaaag
    56821 ctctgataaa attctttcta tttcctcttg ctctcctagt ttcaactgcc tcaattcatt
    56881 gttcatctct actatagtca ttggctctat aaaaagtgtc gcaccagaag atgactggtc
    56941 atgcactata ccagctactt gcgacctata ttcagatttt acaggtacta caaatctatc
    57001 acctcttaga gaaattattg catcttgtaa gtacttttga taagtagttg aacttattat
    57061 tgaatttaat tttgacctaa tggattgatt tttttgggct attcttcttc tgatatctct
    57121 aagtgtactt gaagcattgt cagatatttc tacttcacta attatagcat tgtatatctg
    57181 gtcttctatg tccttgtata catacagaga atttgataga gattgtatta ttggataatt
    57241 aaaatcttct tcatcactac tagataagct atttcttaat cttctagcca ctcttaaggt
    57301 atctgctatc ataatcagac ttcctgggtc aagagaagca cctatataag ctctctttac
    57361 cttatcttct atatcatgaa taccttccaa ccctactgaa cctctcttta taataattga
    57421 ttgagcttca ctagtttctt ctagcataga tttcacttct acaaaatcag tatttggtac
    57481 taaattttct atatatttta gacctaaaga agatgaggct ttcttcttta acaaatctat
    57541 tattttattg tattctagaa ctcttaacga tttctcattc attttctata ttcaccatcc
    57601 tcgatatttt aactttttta tttaatttta aaaatgtatg ttttcaagca tttccaataa
    57661 aaactgcaag ttttatttct ttttcatttc taaaattatt atattttttc tcttttagat
    57721 atattttaca catattttgt attatactat gtatgtagct atctatatat tatacataaa
    57781 catgctttat ttgtaatata atctgttaaa aaatcttctt taatattttt aaaggagttt
    57841 attttagctt ataaaaaaaa atagctactt atatagataa attaaggagg aacatgagtc
    57901 atgggaaacg tattagaagg attaaaacca gaaagtgttt ttaaaaactt tgagaaaata
    57961 tctcaaattc ctagaggttc tggaaatgaa aaaggcataa gtgatttttt acttagcttt
    58021 ggtaaaaatt taggtcttga aactattcag gatgaaagct taaacataat aataagaaag
    58081 cctgctacaa aaggatatga aaattgtcca ggtgtagttc ttcaaggaca tatggatatg
    58141 gtttgcgaaa aagaaaagaa tgttgaacat gattttctta aagaccctat aaaattaaga
    58201 attgatggtg acatgatata tgctactgga actactctag gagctgacaa tggtatagct
    58261 gttgctatgg gtatggctat attagaagat aatactttag agcatcctgc actagaagtt
    58321 ttagttactg ttaatgaaga agatggtatg aatggtgcag atgcactaga ccctagctta
    58381 attaaaggtc aatatatcct aaatatggac tccgaggagg aaggatactt attagttagc
    58441 tgtgctggtg gtaaaacttg tgttgttagt ttacctgttg aatacaagga agttaaaggt
    58501 gacaaacaag gattattagt tgaggttact ggactattag gtggacactc tggtatggaa
    58561 attgttttac aaagagcaaa tgctaacaaa gcaatagcta gagtattaag tgtattgaat
    58621 gttgattatg aattagcttc tgttgatggt ggtactaagc acaatgctat acctcgtgaa
    58681 gctaaatgtg taatagctgt taataaagct gatgttgaat ctgctaaaaa acaaataaat
    58741 gacattttaa ctgcatttaa acatgagttt actacttctg accctggcat gacttactca
    58801 gtagctgaaa cttctgtaga caaagttctt actaaagatt gtaaagaaaa agttgttcaa
    58861 atgtcttgct taactcctca tggagttcaa tcagtaagtc ttgatataga aggattagtt
    58921 gaaagttcta ctaacttcgc tataattgaa actaaagaat ctactattga atttttaact
    58981 tctgttagaa gttctgttat gtctattaga gatgaaatcg ctgatagaat aagacttttg
    59041 gctcaagctt taggtgctaa ttacgacctt atagctcaat acccagcttg ggaatttaaa
    59101 aaaggctcaa aattagaaaa aatatgcagt gaaacttatg agaaattaac tggtaaagtt
    59161 cctactgtta tggctctaca tgctggtctt gagtgtggat tattacttga taaacttcct
    59221 catgctgaag ctatctctat aggaccagat atgtttgatg ttcatactcc aaatgaacat
    59281 gttagtatcc cttctgtagc taatgtttgg gattatgtta ttgaaatatt aaaatctatg
    59341 aaccaatatt aaatttaagt tttgattcta agtagatttt aattttaagt aatctatata
    59401 aaattaactc tgtaaattaa tactactgtt agtataatat ttactttcaa tattaactta
    59461 tagaaataaa gcctaatgat agataataac atgtatcatt aggctttatt gtaatttaaa
    59521 tattattaag ctttattctg ttttaaaatt aattcttata ctattttaaa tctatttctt
    59581 ccttgtctct tagaatcata aagagcagta tctgctattt gatacagttc atcatactct
    59641 tgaccaggct ttgctataac tacccccata ctaatagata aactttctcc atttggcaac
    59701 ttaatgagat gaatatgatt gtatacatca ttacatttat taataagttc ttccttattt
    59761 attatatcat tgatataaac actaaattca tctccaccca aacgacctac tatatcattt
    59821 tttgcaaaac tttcatcaag tacctttgca acatcaataa gtactttatc tcctaacaag
    59881 tgaccataag tatcattaat cgacttaaaa taatcaatat ctataatcaa taaagcacca
    59941 tttttttcag ttgataaatt caacaaattt tgtgcagtta attttctaat atatgctgca
    60001 ttataaatat tggttaaact atccctttga gccttatcta acaatctatt cttttcctct
    60061 ttttcagaat caatattaca tattttcccg attacataca ttggtatttt tctatcatta
    60121 taaattattt ttgaagtaac tctaatccaa tgaaaagtat catcaagcat aatagaatac
    60181 atttcagttg ttccattttc ttgtgatttt attacatcaa aaaacttttt attatattct
    60241 ttccttattt tatctctttc attttctata ttgccatttt cactttcctt atcattttta
    60301 tccaaaccat aataagtctc aatacccttt tctggcatag aaattatcaa tttatcttgc
    60361 ttataatcat actcaaaaaa gtattcactt gtcatttcat acaactgagt atgttttttg
    60421 agttccaaag atatcttctc gttcatactt gtacgagtat gtaaaccaaa tgccataaat
    60481 ccaataatac aaattaataa actggctaca ataaaaatag tctcaattgg attctgttgc
    60541 ataatataaa gcaacgagaa atcttgtcta tatgtagtat tttggtagac aattgattgc
    60601 attttttctg atgaaatact tataatagct ttattaaata tattcaataa ttcttgttta
    60661 tcttttttaa ttataccaaa acaaatactc tttgctttat aggtttgagg aactagacgc
    60721 acatttttat acttaggttg attcatatag tactgcatag aataaccttc gccataagtg
    60781 taatctgcat agcctttatt aacagcttct atacactctt ctaaattatc ataccaaact
    60841 atattctctt caaactgacc ataataatta atacctttgg ctagagctac acgttttcca
    60901 tctaaactat tctcatttaa tttattatta atcatcatag tatattgagt agaaagaaaa
    60961 ggccgagaca tagctatatt atgttcacga gagtattcat aatcataaat cattcctgct
    61021 acaatatcaa tttcacgctt tttagtcatg ttttctaaat cttcttgaga ttttacaggc
    61081 acaagttcaa attctaagcc tgttttatca catatatgat ttaacaaatc aattgatata
    61141 cctcttaatt cacctgtatc tttatctata ttttgaaatg gtggtttgtt taaaagtact
    61201 cctactttta atttttctgt ctctttaatg taattagttt cttcatcaga taaaaacatt
    61261 tgattattct ctggtgtaaa gtatttttca tataaagtag ttgaaaaata tgggtctttc
    61321 tgttcaatat tattaattgc tgagttaagc ttttgagtta aatttgtact acctttagga
    61381 gtaatgaaat aaaatggttt tgatgaaaat tttgctacag tacgtacacc ttctattggg
    61441 ttcatactca cattaagaag tacatctgct ttaccactct ttagtgcttc tagttgctca
    61501 tcatttgttt tacaatatac caattcaggt gacataagat tcattttaca atactcatct
    61561 aattctttaa gtctagtatc agaattttct attacagcaa tacggatttt tttcacatct
    61621 tgtgaactca ttatgttatc aatatctgta ttttcatata atgcttgtag tactgtattt
    61681 gctactccat aattattccc tgcataatta tatatttttt gcattggttc attgtataac
    61741 atacctccca ttatatcaat ttcaccattt tctaacatct tcattaattt tgtaatagat
    61801 tcatttatct ctccaggaac ttgaacaaat tcataattcc atccagtata ctgtgcaatt
    61861 tctagtaaat attcatatgt atacccaaaa tagttacctt gctcatctat ttcagttaaa
    61921 cctttttgaa taggataagc aacacgaatg gtacgattat cattacctat agcgttgata
    61981 ccaaaagaaa atatgcaaga agtgaatata gatgtaatta caataattaa taaaagtaat
    62041 ttttttaaat tcactacaca atcctccata tagttaagat ttacagtata aattactgca
    62101 taaacttgta gacatgtaaa aatagattag tatataaaag gatatataaa tctacttaga
    62161 aatttaaata tccttaatat atacaatata tttaaattat aactcattta tatgtctatt
    62221 acaacaaatt taccctgcta aatacctact ctatatccca taattttaca agttgtagtg
    62281 aagtttaagt tctatctcac ctcaaattta gcagtgtttc tatttacagt tcttttatat
    62341 ttcacatctg gataacccaa tataaatgaa gtgataacag cttcgttctc gctcattcct
    62401 aacagttctt ttatctttgg ctctacattt gatgccataa caaaaaatcc attataacaa
    62461 attcctaatc cttgagaata ggccataagt tccatattag atgcagccaa tcctccatct
    62521 acataagcac ttccacctag agacatatca cctacaacta ccataagtag tggggcatca
    62581 taaaataaag aatcatttcc gttctctttg tatcttttgt acattttctt aaatgtattt
    62641 ttatacatag aacgtacagg gtcattgtca tcagtatcta atgccaaatt ataaagacct
    62701 tgtattgcca gttctttcac ttcttttagc ttttctttta ctaatatgta tcttataggc
    62761 tgtctattac cacctgttgg tgtgtatcta ccagcttcca ctatgttttt tattttttct
    62821 tcttctacct ctatatcttt atattgtctt atacttcttc taaatttaat aaaattcaat
    62881 aacttttcgg gttctaattc aaaactttca cgattgtatt ctattacttc atttttatca
    62941 aatccttgca tttctattgc atctgttggg caaattgcca tacagtgacc acagttaata
    63001 cagagaatat ttttaacctt tgctttatca tccttaactt ttattgcatt tacaagacag
    63061 tctgattcac acataccaca gcctacacat ttttctaaat ttatgtctat cattccaaat
    63121 tattcctcct tttaaaaaat ttactttagt ataaaacaaa tagttgtcta agtcaatttt
    63181 tattttttta acaatatact agccttaact acactttaat ggagaaaaat atacataaat
    63241 tggaacttaa attagaactt attcaaagta aaagataaaa gaagtagatg tctaaaagtg
    63301 aactttttag ttaattagat attctttatt gtatgaaatc aagtggatat ttatcatttc
    63361 aacaataaaa aaggcttacc tctattttgg atatgtccct gtcaagtaga cagactaaaa
    63421 aaaggctatc tttatgcact gagatagccc cttttcccaa ctactattgt ttattttaat
    63481 attatatcaa taaatttaat ttgctataac ctgtaagtta cattttaatt tgatgtaact
    63541 ttaaattaca tttttaagta gtatctttaa attatattct taaaatatat cattaaacta
    63601 cattttaatt aatctaaaaa ctatatctta attaatctaa gaaacttaca ttataatctt
    63661 ttagtttccc attatcatat acaatctttg cactaaagat atttccagtc ttagcccaat
    63721 ttaagaacag cctgtcacct tcccacatat ttaaatcgaa tattttatca ttatcaaccc
    63781 aaattaaatt tccttcttta caatcattta aatctttttc agataattca ccttcaaact
    63841 catctgagaa atacaaaaac atataccaat cttcttcatc tttaaatttt ggaaaagtta
    63901 tcaacccttt atatgacaat gatttaagag taagaccagt ctcttctttt acttctctaa
    63961 ttacacattc ttctggagtc tctccttgct caaactttcc tccaactcct acatacttac
    64021 cttcatgtat atcatctttc tttttatttc tgtacagcat caaagtcttg tcatcttttt
    64081 ctatataaca aatagttgta agtttcatgt atctcgcctt gctttctctt ttatattctc
    64141 aactaattat tttcagcact ttcaagcaca tcacttatat tcttcattgc attaagagaa
    64201 agctctgcaa attcatcaaa tggaatccct atatcttcta tacttctcat tgcatctcta
    64261 tttacatttg aagcaaatct cgtttctttc attcttttaa taacagactt agtctttaca
    64321 ctggtaagtt ttttatctgg ataaactaaa gctatagcag ttataaaccc agttataggg
    64381 tctgctgcat atattgcttt ttccattagg ctagttcttg taactcccat tccatcatga
    64441 tgaccaagta ttgctctata catttcttcg tcaccgaagt tttctttttt aagcagttct
    64501 actgttgttg tagcatgtcc ttcacatatt tctcctggct ttcttccaac tatatctgaa
    64561 tccaaatcat gtaaaagacc tgccactgcc cactcttctt ctttttctgg ctctagtctt
    64621 ttggctaatt ctctcataac agcttcaaca gcataacaat gttttctcat tctatcagtt
    64681 tctaaatact taaataaaat ttctaaagct tcttctctca ttttcaccaa tccccctgtt
    64741 ttttcacata tatgatattt ttatatatta atacacataa attcaagttt ttatatatat
    64801 tcatgtatat ttttcatgtt atatctattc tacaccttta tagtagtgtc ctgcaactgt
    64861 tccaatttca tctaatttct tatacaagtc tgtagccttt tttccaagtt tataattatt
    64921 actcaatacc tcaatgtgag cttcaataac ctttttaacc atctcactat cttcaactgt
    64981 aaaatctatc ctaaatacat ctattccaat ttcctctaac tcatatagat tgtccaacat
    65041 acaagtaacc ttcgaattgt aaattgtact tctacagaat atatcttgtg ttatcctata
    65101 acttgcatcc gtaaagtctc ttaaagcata actactttcc ttacatttag caactctctt
    65161 gtccttttta caatctctaa caactactcc cataggacag tattctgtaa ccatcatagg
    65221 agcatatcca tatattactg cttcaatttc tacatctgta tattttaaag tttgtttaat
    65281 ttcatttaag tttagttctt gtgacaaaca aactgtactt gctccctctt ctttgaagtg
    65341 atttatactt tcactattga atgcatttaa gtagcaatct atatttaagt cttttttctt
    65401 aaagtattcc atagagcccc agttaccaat ttgaacctta ttaattcctt ttatattatc
    65461 caatatctca aattgcttgt actctttatt tctaacaatc cttggtgctg aatagattaa
    65521 ttttttgtca gtgactgctg tattatagtg gttcttattc aaagtatcta ttttacttgt
    65581 atttgacaaa gtatctatgt tatttgtatt tgaacccatt agttctttag gagtacctaa
    65641 agacgaagaa gtatctaaat ccatagaaat acttgaatct atagaaatat ttgaatctat
    65701 agaaatactt gagaccattt gtaaagcttt tgataatgta tttatatctt cataatagat
    65761 taaatctaca ttataattta atactgcttc taattgctcc aagttcttaa ctttaactct
    65821 aatcttagga gctgtatcaa gttttttctg tttatttact ctatttggct ggtattttaa
    65881 tctattcttc ttaaattttc tatcttttat ctttattctt tcttcatcta aaagctcaat
    65941 acaatccctt ctcatctgat ttaacacact tataggcata cttacacctt catccaggtc
    66001 aatttctatc tcttttaact tatatggtgt atttccaagc ttttgaattt gtgtttctat
    66061 tttttcttta cttaaagcca cctttatagc tttttcaact attttgtctc cttctaccac
    66121 cgatttattt ccacaaaaat cacttataaa aagctctggc tttttaccta gtttaatact
    66181 cacttttgca cgtatattag tttttatgaa ctctttatct tgctgaaatg tagcttgtac
    66241 tctatccatt aattcgctgt cagaagtctt atatataagc tgatttctct ttgcttctcc
    66301 aacaaaatct aattctatca aatccccttt atgtgctatt gtagttatct ctccatcctt
    66361 tattattctt ccaatagtac ctccacctaa gttaattcca tcacctttct taagcgtatt
    66421 ttctagcatt actctaagtc ttttgttctt tctattataa tctaaaactt ttccaatata
    66481 tagcccttga ttattaggtc tattagagtt cattatatcc ttaccaactt cacctaatat
    66541 atatcctttt gtaaactttc tattaaatat ggtatacaaa ttatttatta tttcctcaga
    66601 aatacttatt tttttcttat ctacaaattc attaatcgct tctctatatc ctgaaaccac
    66661 agtagctaca tactctggct ttttcattct accttcaatt tttaaagata atacacctgc
    66721 ttcaattatt ttatccaaat cttctatagt acttaaatct ctaggactca acaaataatc
    66781 tccattactt tttactactt ctcctgtatt tatatctatc aactcatact tttgtctaca
    66841 tggctgtgca cacctacctc tatttcccga cctattgcct atcatactac tcataaggca
    66901 ttgacccgag taacatacac ataaagctcc atgtacaaaa acttctatat ctacagttgt
    66961 attttcacaa atccatttta tctcatcaac atttaattct cttgctaaaa caactctatc
    67021 aaaccctaca ctctgaaggt attttacatc ttctaaggaa tgtgctacca tttgagtgct
    67081 tgcatgtagt tcaaagtcag gtaatagttt ttttataagt cttgccattc ctatatcctg
    67141 tactattaaa gcatcaatat ctatatcgta taaaaatttt acatactcta caaaatcttc
    67201 tatttcatac tgttttatca atgtatttac agtaacaaag acttgcactc cccttatatg
    67261 agagtattta acagcctcaa tcagctcatt tctatcaaag ttatttgcag atgctctagc
    67321 actaaagtct ttaccaccta aatacacagc atttgctccg ttttgaactg ctgcttttaa
    67381 tgaatcaaaa gagcctactg gtgcaagtaa ttctattttt ttcatatttt tctcctctat
    67441 ttatacttgt taggttaata taattatatc tataacttaa atatttgtat taaatttata
    67501 tatttcttac tatattttaa attcttcaat caatttatat attagttatt tatatttggt
    67561 tcatt
//
LOCUS       DAMKNB010000012        64726 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.012, whole genome shotgun sequence.
ACCESSION   DAMKNB010000012 DAMKNB010000000
VERSION     DAMKNB010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 64726)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 64726)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..64726
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.012"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            167..1162
                     /gene="ilvC"
                     /locus_tag="PC494_000914"
     CDS             167..1162
                     /gene="ilvC"
                     /locus_tag="PC494_000914"
                     /EC_number="1.1.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HDF3911435.1"
                     /translation="MKMARMYYEKDVDLEVLKNKKVAVLGYGSQGHAHAQNLRDNGVH
                     VVIGLYDGSKSAQKAKEDGFEVKSVAEATKESDLTMMLMPDEKQKKVYEESVKDNLKE
                     GQTLAFAHGFNIHYNQVQPPEFVDVVMVAPKGPGHLVRNVFTKGSGVPALFAVYQDYT
                     KKATETVLAYAKGIGATRAGVLETTFKEETETDLFGEQSVLCGGISELIKLGYKTLVD
                     AGYQKEVAYFECLHEMKLIVDLIYEGGFERMRYSISDTAEYGDYVSGKRVITDVAKQG
                     MQNVLEDIQNGKFAKAWIKENEEGRENFLKTREEEYNTEIAEVGRNLRSMMSFLK"
     gene            1215..2903
                     /gene="ilvB"
                     /locus_tag="PC494_000915"
     CDS             1215..2903
                     /gene="ilvB"
                     /locus_tag="PC494_000915"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biosynthetic-type acetolactate synthase large
                     subunit"
                     /protein_id="HDF3911436.1"
                     /translation="MNGAKVILECLKKEGIDTIFGYPGGAVIPLYDALYDYSDDFKHI
                     RTSHEQGLVHAADGYARSTNTVGVCFTTSGPGATNAITGIATAFMDSSPMVVISGQVP
                     TSLLGKDSFQEIDITGATLSMTKHNYLVRNTKELVPTIKEAFRVANSGRKGPVLVDVP
                     KDLFLAEMDFSGEDYDLCQIDDYMDYKSDFDLDDETNIKLLNEAIDIIKESKKPIIYA
                     GGGVKSSDSEEILEKFATKIDTPVLNTLMGLGNIDRKNELSLGMVGMHGSRESNLALS
                     NSDLVIAIGARFSDRVISKSSEFAKNAKIIHIDIDPSEISKNIESNVSLVGDVKLVLS
                     LLIERVESKNNSNWKEEIKRFRKSEGVQTYEFHPQNILKKINEKYETLKKPTVVVTDV
                     GQHQMWAAKYWNFKGNKSFITSAGLGTMGFGLGAAIGTKVGNVDKNVVLVTGDGSFRM
                     NCNELATVANYNVPMLILLLNNRTLGMVRQWQKLFSNQRYSQTDINENVDYVKLVNAY
                     NIDGYKVSSMEELGKALDMIDFNKPVFLQCDIDKDYDVYPIVAPNDALENLICN"
     gene            3114..3791
                     /locus_tag="PC494_000916"
     CDS             3114..3791
                     /locus_tag="PC494_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese catalase family protein"
                     /protein_id="HDF3911437.1"
                     /translation="MFKHDKALLKEVKVERPNPQYAVLMQEQLGGANGELKAAMQYLS
                     QSFRIKDPQIKDLFLDIAAEELSHMEMVAQTINLLNGHDVDYNAVNTGEIETHVLTGL
                     SPVLINSSGAPWTANYVTVTGDLVADLLSNIASEQRAKVVYEYLYRQIDDKYVKETID
                     FLLNREEAHNALFRDALNKVKDTGSNRDFGVTEDSKLYFDLSTPGPNHDTKIDINPPS
                     FEKPLKK"
     gene            3965..6001
                     /locus_tag="PC494_000917"
     CDS             3965..6001
                     /locus_tag="PC494_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin domain-containing protein"
                     /protein_id="HDF3911438.1"
                     /translation="MDSNRKPNNLINEKSPYLLQHAYNPINWYSWNDEAFKKAKEEDK
                     PIFLSVGYSTCHWCHVMEKESFEDEEVAEIMNRNFVAIKVDKEERPDVDSVYMTVCQA
                     MTGSGGWPMTIIMTPDKKPFFAGTYFPKYSRYNRPGVIDLLENVSEKWNTSRDILIKS
                     GDEIIEALKDDFGVKNTEGDLSKEMLSSSVRVFKAIYDEKYGGFGNAPKFPSPQNLMF
                     LMKYYSIEKDKDVLKMVEKTLDGMYRGGLFDHIGFGFSRYSTDKKWLAPHFEKMLYDN
                     AMLTIAFLDAYKITKKELYKEIAIKTIDYVVREMKDKEGGFYSAQDADSEGEEGKFYT
                     FNPLEIIEVLGEEDGTFFNNYFDITSSGNFEGKSIPNLIKNKEYERHNEKIADLSKKV
                     FEYRKERTSLHKDDKILTSWNALMIVALTKAYSTLKNDIYLEYSNKCLNFINNNLVNE
                     SGRLLARYRDGSSDYLAYLDDYAFLIWAYIELYESTFNMKYLEKALNLNESCINLFWD
                     YEKSGFYIYGKDSENLIARPKDLYDGAIPSGNSVQLYNLIRLAKITGDNRLEEMSYKQ
                     LKLYVDNVKSSPTGYSFYMLSLMFELYSTKEIICIFKEDSDLIAFKELISENFIPNAT
                     FLAKKYNEENTIIGFLNNYRLKDDKISYYVCQSNSCSQPINDLQKLKDMILGVE"
     gene            complement(6192..6758)
                     /locus_tag="PC494_000918"
     CDS             complement(6192..6758)
                     /locus_tag="PC494_000918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HDF3911439.1"
                     /translation="MDYSNELKELFLMNQTYATLFTLTNKIQIEGDKYFGILTSRQYM
                     TILSILHLPEEETTLNNIARKMGTSKQNINRLVANLEKNGYVDVIPSPHDKRAINVKV
                     TDLGKKVMVTCSRTGINFMADVFHEFTKDELETLWSLLKKMYRFNGEEQDGFEEDANF
                     MEYEEIDKIKSEALEEFAKRRNRVNKKD"
     gene            complement(7055..8248)
                     /locus_tag="PC494_000919"
     CDS             complement(7055..8248)
                     /locus_tag="PC494_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005336078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HDF3911440.1"
                     /translation="MKEKRRDSKGRILHTGESQRTDGKYLYKYVDAFGNTKYVYAWRL
                     TPTDPTPKGKREKPSLRELEQQIRRDIEDGIDSTGKKMTLCQLYAKQNTQRANVKKST
                     QKQREQLMRLLKEDKLGARSIDTIKPSDAKEWALRMKDKGFSYNTINNHKRSLKASFY
                     IAIQDDCVRKNPFDFKLSEVLENDTKEKVALTEEQEQALLSFIKTDNVYHKYYDDVLI
                     LLKTGLRISELCGLTVADIDFKNEVVIIDHQLLKSKEQGYYIETPKTKSGTRQVPLSK
                     ETIQAFQRVMKKRPKAEPFVIDGRGNFLFVNQKGKPKVAIDYNALFVRMVKKYNKHHK
                     DNPLPHITPHTLRHTFCTRLASKNMNPKDLQYIMGHSNISITMNWYAHASIDTAKSEV
                     QRLIA"
     gene            complement(8327..8530)
                     /locus_tag="PC494_000920"
     CDS             complement(8327..8530)
                     /locus_tag="PC494_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HDF3911441.1"
                     /translation="MNNNDIPVWEKYTLTIEEASKYFRIGENKLRRLAEENKDAGWLI
                     MNGNRIQIKRRQFEQVIDKLDAI"
     gene            complement(8530..9621)
                     /locus_tag="PC494_000921"
     CDS             complement(8530..9621)
                     /locus_tag="PC494_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018594174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HDF3911442.1"
                     /translation="MTTHKNLSVKIDYISIVFDTATAEDVIMHILGLPTDIFNVYPAS
                     VKYKTYQARWQIGDIYVSGDARKTEDNPQGLGCYLVMTGRGCDDIFRILDSRNYTFGD
                     MFRRCERRYGLDNFHFTRLDIAIDDKNEKPFFTIEQIKKKCEKEEFISNSEGYHFDES
                     KFDDFDTAKTVYIGAGKSGLSYRFYDKDKEVCSKHNKTLDEVGSWKRTEMQLRDDKAH
                     AFAMTFKDRPLELGELAFGLLANNLRFVVPNRNESNKSRWKTCRFWERFLGAVEVLKL
                     QVPKQQNSLEETQQWLTEGGVISAVKSFYFLEEHNALGGLEKVGTMLDKARYSNSLSS
                     KLTAHLQRINRTDLIPYIQYDTKHGKGGI"
     gene            10078..10749
                     /locus_tag="PC494_000922"
     CDS             10078..10749
                     /locus_tag="PC494_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008393244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF3911443.1"
                     /translation="MEHYEKKISFLGENIQTIRKHRGMKQQELADKIGINMQSLSKIE
                     RGVNYPTFDTLEKIMDVLGVTPNELLSGEWKYIDHTEPYIMDIIKREQDFNVSLDYLS
                     ENEFFNDEKECRFYKEYKLIQYIHNYITNEVTELEELMEIKQLIQRQKIERMMKVHKE
                     MRGLDRYREQPKEYKYHDPYDDWIFRQLADIDNRNNIPDTSPQLDFNEADYEDYLKAK
                     WNRGL"
     gene            11003..11383
                     /locus_tag="PC494_000923"
     CDS             11003..11383
                     /locus_tag="PC494_000923"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3911444.1"
                     /translation="MIVFWIIGILFLIVGLIVSVPTIIKFIKCKEHTTGKIVSIDSSS
                     NGYARAVYEYIVSSSKYTNKTNWTPHHIFHLDGECHVIYDKNNPNSSYIKKSGQYIRC
                     IVGILFAMIGIGVLLLGIFLITVL"
     gene            11807..12178
                     /locus_tag="PC494_000924"
     CDS             11807..12178
                     /locus_tag="PC494_000924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005947439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3911445.1"
                     /translation="MWLLGSIFIFTSLLILYIKYRVVFTGEKCKGKIIDIVEQNAGYV
                     VGGVNVKKHAYIVKIKNKKYHTAHGCIFLSLGKRNIGKEISVFKNEKYGNEVFKCFDF
                     RIEIVALLVFLFGVFMIYSAL"
     gene            12252..12776
                     /locus_tag="PC494_000925"
     CDS             12252..12776
                     /locus_tag="PC494_000925"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3911446.1"
                     /translation="MENLSAYRYCIAMKKGRKILNLIVGCLMILISIIFITTTVFSCI
                     FMQEFVYYTFLAIFLIIIPLPLFIFGIIGIVSATKRVEVYKGKVIYHIGFKNKEYRMS
                     DIKTSKTKSETYRTGLDYGNIVPTYSYDKLTVFYDKKGKKIFKFGLAYDNVERLKADV
                     NNTQKSIAKQHNKN"
     gene            12810..13040
                     /locus_tag="PC494_000926"
     CDS             12810..13040
                     /locus_tag="PC494_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011068146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3911447.1"
                     /translation="MAISNINTIISNDIQKVWNIVLAVDKYNSWRSDLSKTEIDFTEN
                     VIPKKCFMKPFVKTYLKKQQKQFVLDLKKALE"
     gene            13067..13387
                     /locus_tag="PC494_000927"
     CDS             13067..13387
                     /locus_tag="PC494_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TfoX/Sxy family protein"
                     /protein_id="HDF3911448.1"
                     /translation="MASSKDYLQFVLEQLSELQEITYRAMMGEFIIYYRGKIVGGIYD
                     DRLLVKPTKSAISYMPAVTYEIPYENAKEMLLVEEIDNKDFLMGLFNVMYDELPTPKP
                     KKKK"
     gene            13793..14728
                     /locus_tag="PC494_000928"
     CDS             13793..14728
                     /locus_tag="PC494_000928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDF3911449.1"
                     /translation="MKCTNFTFKGEEGLDIYTYKWEDENIKKPKAVIQIAHGMAETAQ
                     RYETFAKVLTKNGYIVYINDHRGHGKTAKIIENVGHLAEKEGFRCLVEDMYTLTNIIK
                     KENEDLPIYLFGHSMGSFASQRYIMDYSNNLSGLILCGSNGKQGIILNLAHLIINREI
                     KKYGRRSKSNKINNLIFGGEIIRRNEKTKFDWLSRDKEQVEKYINDPFCGVVCSCGFF
                     YDLVQGLKEIEDKENLKKVPLDIPIYIISGDKDPIGKNGKGVLRLRDRYIKLGVKDVT
                     CKLYKDGRHELLNEINREEVFEDIICWLNNKIEIL"
     gene            15199..16413
                     /locus_tag="PC494_000929"
     CDS             15199..16413
                     /locus_tag="PC494_000929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF3911450.1"
                     /translation="MQIKIGKVIQCLRKERNLTQEQLAKFIGVSTPAVSKWESGNSYP
                     DIELLPLLADFFNVSIDKLLNYKIDLSEEEVMKIYKELESGFARIEIDLSTEEPKEEF
                     RQDLESVKKLSNMYIEKYPKSYLLKLRICSLYQMYSYKFGKSELNDRVKETTNILEDI
                     VRNTDDIQIKETALIILSNAYCMLEDYEKAELYLNMIHKSIGDTSVNLAMIYLKQNRL
                     EEAEILLQNKLFSNVFNISMDCKGIINVYKNQYKELKKKLENRNFNKNAIEREMEYIK
                     NKLLGYANLSLEIKKMLSEDKGAFFSMYMDYMELSLIFLFFNMKEEAKKALYSLKEIL
                     EKYPIHESLDVSQMRFFDKVESKNLYTFNIYTNLLIVLNDDSYNELREEPIFKDVIEK
                     ILDMEKMLKNKE"
     gene            complement(16833..17354)
                     /locus_tag="PC494_000930"
     CDS             complement(16833..17354)
                     /locus_tag="PC494_000930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDF3911451.1"
                     /translation="MKFEWLRTSENKLYYKAMELYKISFPFHEQRKSSLQAEILKNKE
                     YQFNLIYDKNQFVGIILCWETDDFIYVEHFCIFPEMRNNRYGQRALELLNKKGKTIIL
                     EIDLPIDEISIYRKAFYERVKYKTNNYEHIHPPYHKKFNGHNLIVMSYPEKLSKMEYD
                     KFNHYLRNNVMSF"
     gene            17710..18507
                     /locus_tag="PC494_000931"
     CDS             17710..18507
                     /locus_tag="PC494_000931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HDF3911452.1"
                     /translation="MEKREKRIIISSLLSVSILMGLVSIYSILNKEDIILTVKGQEQK
                     VSSFKKTVEELLDEQGVKYNSEDKINPSLDTELKDDMKIKVVKVTKSKKEEIEKIPFD
                     TKHVNDSNLLKGKSKVYQEGQEGEKKLVYNLTYHDGKLVKKVLSKEVISKEPTTKIIK
                     YGTKEKVLIASRGANIRGGKHMKVVATAYAGDTITSTGTTPRWGVIAVDPRVIPYGTK
                     VYIPKLGMTFVAEDCGGAIKGNRIDIFMNSEGKASNWGRKSIDIYLH"
     gene            18617..19207
                     /locus_tag="PC494_000932"
     CDS             18617..19207
                     /locus_tag="PC494_000932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HDF3911453.1"
                     /translation="MKIVCLGDSLTYGFGVSRSNSWTNIVNKETRLEIVNKGINGDTT
                     SGMLARFNEDVVKNSPDIVFIMGGTNDFIAGAGNEIINSNIMAMVHQSYSKNIIPIIG
                     IPLKPDIPNVREDWSCFTDFNIVSQNLESYSYWIKKFCMTFNTNFVDFYSEYNKNMEL
                     EGYKKLYFDGLHPTKEGHRIMADIFINSINKYIEEL"
     gene            19273..20970
                     /locus_tag="PC494_000933"
     CDS             19273..20970
                     /locus_tag="PC494_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HDF3911454.1"
                     /translation="MDYTKTYEEWIKGSYFDEDTKLELENIKNNEKEIEDRFYKDLEF
                     GTAGLRGIIEAGTNRINKYTVRRATFGLANYILENTTKEETSRGVVIAHDNRHKSRQF
                     CIESANTLAACGIKAYIFDSLRTTPELSFAVRSLNAIAGIVITASHNPPEYNGYKVYW
                     EDGAQVMPEIANAITEKVNSIHDYSTIPTLTEANKNLVVLLDESQDTKFIEAVKSQII
                     RKDLVKNVGKSFKIVYTPLCGTGNVPIRRALKEVGFENIIVVPEEENPDPNFAGLDYP
                     NPEEKKALNRGILLAKEKGADLVIATDPDCDRVGVAVKTTTGEYALLTGNQIGGMLTH
                     YIIEGLKENNKLKENPTIIKTIVTSEFGADIAKANNVDVLNVLTGFKFIGEKIKLFEQ
                     NKNRSYVFGYEESYGYLVGTHARDKDGVVSSLLISEMAAFYYSKGMSLYDGLIELYKK
                     YGFFKEQTISLTLKGIEGVEKIKEIISYFRENQIDYINSIKVVDKKDYKNGIDNLPKS
                     DVLKYFLEDESWVAIRPSGTEPKLKFYIAVKGASDIEADKKIQGLKKYIDDMVEKLK"
     gene            21184..22023
                     /locus_tag="PC494_000934"
     CDS             21184..22023
                     /locus_tag="PC494_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HDF3911455.1"
                     /translation="MFGIDKKLIEYIIAKSNYSELSSKSAEVSFFLMLSIFPFLIFTI
                     SSIAYIPILHLNKYIALFRNMMPEGAFAVLSSIIVSAIDNRNLKFLAVSFVLTMWTFS
                     RAVKALIKGMNRAYKVKETRSFFKILSISFLFTIMLLVLIFLSMIFLVYGEKIGYFIF
                     NLVGLDEIFIKIWDILRYTVGIITIIVIFTLLYKYTPNKKLTIKESAPGAIFATFAWF
                     LVSFLYSYYTNYYANYEVIYGSIAEIIVLMTWMYFSSWSIVIGYEVNSRLYFRKIRHE
                     MLK"
     gene            22540..24396
                     /locus_tag="PC494_000935"
     CDS             22540..24396
                     /locus_tag="PC494_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PAS domain-containing protein"
                     /protein_id="HDF3911456.1"
                     /translation="MDTHNKYVNFIKNIPVPFLYCRIVKRQEDIEYRVEYISKGMGKV
                     LQLEEGICDKNILDVLPVFKSKKYFKELFSNEVDCIKRYIPTLKNWINIKKQIIGDSY
                     IILYFGKIVFDYRQIIDSFDKKEKVAYIKDEEGIYIDCSENLIPILNNNIKTTKDIFG
                     KNDIEVWGENTGKLFRDDYREGVSSKKRFLQNLFEYEETFFMVEKYFLYDEDELLGTI
                     GIVDNIIYSGYSNRNYNSKDLMKMIEHSIPENMFYKDVYGNYIGFNSGFLNLACMNKE
                     ELLGKNSYKISEEEALIDKIFESDKGVVENKKVVTFELNISMNDENKCIEITKRPFFD
                     SYGSVIGIIGTARDISRRKRLEEEMDKTRMEFFANLSHELRTPINLISSSLQVIEKKE
                     ADLIESNDTLKRNLGIIKQNGNRILRLVNNVIDFTKMQSGYLDFKPEESDIIAFIEEI
                     CMSVADFASQNNIQLTFDTEIEEFSMLFDSEKLERIILNLLSNGIKYNKKDGKINIFL
                     YVKDNVFNMKISDSGIGIPKEKIDKIFNRFEQIDNELSYRVKGSGIGLSLVKSLVELH
                     EGSISLKSQLGIGSEFIVSLPVRSKNNIEKYNHKREISNELSKKLEIEFSDL"
     misc_binding    24479..24719
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     misc_binding    24785..25020
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            25105..26322
                     /locus_tag="PC494_000936"
     CDS             25105..26322
                     /locus_tag="PC494_000936"
                     /EC_number="1.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine dehydrogenase"
                     /protein_id="HDF3911457.1"
                     /translation="MENKVKIGVLGYGVVGSGLIDIIDNNKEKRNIEIVGILVNNLEK
                     HKDKKYSNIITNNIDDIFNKDIDILVEVMGGLEPSLSYIKKALNNKIHVVTANKDLLA
                     ECGDELAKLASENKVSIKFEASVAGGIPVLKPIIESLEGNNIDSINAILNGTTNFILS
                     KMYDENLSYDMALRQAQELGFAEANPESDVLGYDAARKLSILSTLAYDNRVYWKDVYL
                     EGITDIDEKDIEYAKKLNCKIKLIGQSKYENDKVSAFVRPVLVEKDNILARIDNEFNA
                     VIVNGDSVGEVSFVGKGAGSLATGSAVYSDVIDIIDNRVSSIDSFTKDKIQVNKIVRE
                     KCGALLRFKKCNKDEILNIVENCLVKFDILNDDDELAIMVYADSEYEINNSLCLIKDK
                     GYCEKMNKMLKIS"
     gene            26439..26921
                     /gene="cdeM"
                     /locus_tag="PC494_000937"
     CDS             26439..26921
                     /gene="cdeM"
                     /locus_tag="PC494_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exosporium morphogenetic protein CdeM"
                     /protein_id="HDF3911458.1"
                     /translation="MENKKCYSEDWYERGESTAKWFQNDREEYEREAYDEDRERRGSN
                     CGCSDSGENRPRNCERFRREAEIREREAREAFCESSEKKKEALAYECEARKLWEEAEK
                     YWDEYSKYNYKGIEYLAEAARLFDEGMECEARRNGNNGGNNNNCCHKCHKCNCNCCRK
                     "
     gene            27186..28451
                     /gene="hisD"
                     /locus_tag="PC494_000938"
     CDS             27186..28451
                     /gene="hisD"
                     /locus_tag="PC494_000938"
                     /EC_number="1.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol dehydrogenase"
                     /protein_id="HDF3911459.1"
                     /translation="MKSIKTSSMKEKVDEKILREQVSSIIEDIRNNKDVALKKYNEKF
                     DRNTRDEFRITKEEIKEAYKHVDDEFINNLKIAAKNIREFAKAQKLSFENPFEKEIYP
                     GVILGQTNIPIESCLAYVPGGQYPLFSTALMLIIPAKVAGVKRIVACSPTMKNTEKIN
                     PKTLVAMDIAGADEIYATGGVQAIAAFTYGTEKINPVDIIVGPGNKFVTEAKRQCYGQ
                     VGIDFVAGPSEVLIIADETSNPVYIAADLLAQCEHDLNARGILLTNSLEVAQKVEKNI
                     ESMLKDLPTKDIAYSSWENNGEIILVDDMEEAIKISNFYAPEHLEVAVNEYNDICDRL
                     TNYGSLFIGNLSAEVFGDYVSGTNHTLPTLKASRYTGGVWVGTFIKTCTKQIFNEKAI
                     QSLAPVAEKLAKEEGLYAHAKAAEVRFKK"
     gene            complement(28654..29406)
                     /locus_tag="PC494_000939"
     CDS             complement(28654..29406)
                     /locus_tag="PC494_000939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDF3911460.1"
                     /translation="MSYFQYQGNSCFYKEYGQGKPIIFLHGNTGSSNMFKALVPLYAE
                     NFRCILIDFLGNGQSDRVSQFSPDIWHDEALQTIALIEHLNCGKVGLIGTSGGAWAAV
                     NTGLERPDLVEAIIADSFDGRTLNDNFIDNLITGREKSKQDIQARKFYEWCHGKDWEN
                     VVNLDTKALLQCANEKRPLFHKELCKLEMPILFTGSKEDEMCRHNLEEEYKQMATFIS
                     KASIYIFSQGGHPAILTNADEFAQLAKVFFKY"
     gene            complement(29524..29793)
                     /locus_tag="PC494_000940"
     CDS             complement(29524..29793)
                     /locus_tag="PC494_000940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3911461.1"
                     /translation="MSYQNSIDLLPKELIEQVQEYIDGKVIYIPKKQEHKKHWGENTN
                     TKQVLASRNSQICINFQNGMSIKQLSEKYFLTEKSIQRILKQQNL"
     gene            30268..31362
                     /locus_tag="PC494_000941"
     CDS             30268..31362
                     /locus_tag="PC494_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HDF3911462.1"
                     /translation="MKNIVGKPQTIKKVNEDLIKNIIKNEGPITKPEISSITELSLAT
                     VNKIVEQLALKNEVKVSGLSESTGGRRAQLFEINANLEHIIALYYYRNCCIGVVANLL
                     GEIIYQEEFNIRMDTYENVNQDTFFVIDTLIKKEKGNNIRAIGIGVPGVVKKGVVKNI
                     PTIKSWEGINLENLIKSKYNTKVFIENDTNITTIGIYQKQYKDKYKNMALMYLEDGIG
                     SGIVINGELYLGSTNFAGELSYLNIEFGKYNSNNLNLEDYIMSLRKRYLESKDNKFKK
                     EILSIISNFIRTLVCVLNPQAMIIQCSILTKSDMEFIEKDVSNNVGEENFPKLIKVDS
                     LREGSINGVISMCLKETDYQYSLSNKKGGY"
     gene            31364..32314
                     /locus_tag="PC494_000942"
     CDS             31364..32314
                     /locus_tag="PC494_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine kinase"
                     /protein_id="HDF3911463.1"
                     /translation="MKYLVSIDGGGTKTKFCVSDLDGNILKEHTTGSTNYKSVGIKKT
                     YENINNGFKKILKDLYIDYDDIEYTVFGISGCDSPNDYKIIMDEILKIGINKEKIYLA
                     NDAVLAFYAQADSPGLVIVAGTGSIILGIKEDGEIYRVGGWGYNFSDLGSGYDIGRKL
                     LKKVLLYCDECHEYSDLFSCVLDFFGANSFEQLAYMITDINDNVEIANLASLVIDCAE
                     QGDKLAIEILRESSTELSKLAQVILRKISNPMKMDKSEINIVLSGGTLNKTVYAQMLM
                     NNLKTENTDKNLKFISQENQPVYGGIRLAMALANRRVKHG"
     gene            32307..33491
                     /locus_tag="PC494_000943"
     CDS             32307..33491
                     /locus_tag="PC494_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3911464.1"
                     /translation="MDRKKVIVQIFTGGFKAKEIKFNDIKCKLLELLDCIDIEKVIMG
                     WSVDEELYVETKKLLNKYNVELYLWLPCFSEIGLLEKSNLLIDYMGKEVKGYALQEDE
                     NFEFYCPNNKENIKNIKKIYSTYFSDIKFDGIFLDKIRYGSFSNKLNGVFNCFCKDCL
                     NIYKKNNIDKESLMREMNNVSKGVIDNEDTPFGITEYINGKYKFKNKIWEDFFETKNQ
                     NIYKALLEISSYFKSKGLKIGIDAFSPFISYFTGQDLEKLQEVADFIKPMMYRTTKAP
                     AGLPFEFERFIDESIHKNKEIGKRNFLDILGIKEYEGDVYPIEFVLEEIDFMTRNLNK
                     DIYVGVEINKKEIISPVTPKYISENISNINKTTVKGYVLSWDLLSAPKENIDEIIKWF
                     RN"
     gene            33504..35000
                     /locus_tag="PC494_000944"
     CDS             33504..35000
                     /locus_tag="PC494_000944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter ATP-binding protein"
                     /protein_id="HDF3911465.1"
                     /translation="MSKILEIQQIYKSFGKVDVLKGINFELEKGEVRALLGANGAGKS
                     TLIKILGGVHSQTKGKVILTGNEIMFKNPHHSKENGISIIYQELSLIPTLTVLENIFL
                     GREILKGSVFLNKKDMLEEYMKICEDFDFNIDPHIVVSNLSVANQQMVEIMKAVSCNS
                     EIIIMDEPTTSLTNNEKDGLFKIISRLKSKGKTIVYISHILEEVFKVCDSASIMKNGI
                     MIGTYDVEDLTKLKITQLMTGNDNHKLIEKKDYTFAKYEEPPVLEVKNISWSNKIKNV
                     SFKVYRGEVVGLAGLVGSRRTEIINLIFGIDNKDSGDIFINGKKVDITSPKVAIKNKI
                     GLIPEDRKNLGLILEQAIYTNSSSVQIDKFKKFLFIDRNKEIEFSKKGVKELGIKVSD
                     VKQEVKELSGGNQQKVVVSKWLEKDLDLIIYDEPTKGIDIAAKEDIFNTIKEFSSKGI
                     GVIFISSDLEEVIRVSDRILVTREGSIVDDLKNENIQVQDIMNSIFNV"
     gene            35023..35973
                     /locus_tag="PC494_000945"
     CDS             35023..35973
                     /locus_tag="PC494_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF3911466.1"
                     /translation="MKKAFEKLNLRDYGVLLGFLALCIAISIATPSFLGKQNILNLLR
                     QSSIIGIISAGMTFVIISGNFDISVGAVAALAGAITMKFATGGTNLFASMFLGVAICA
                     VIGLINGIVVAKINVPSLIATMAMVTIVRGLLLMLTGGYPITENIPILDYIGNGYLFN
                     IPIPVVIFFIVVLASFIVLNKTKFGRYVYSVGGNQEASKLNGINVDSHKVKVFIINAV
                     LAGIAGIVLTGRLGTATAIAGEGYDMDAIASVVIGGTSVAGGSGSVLKTVIGVLLMSV
                     INNSFNLLGIDVYFQYIFKGLIILAAVGFDSYSKKKLASR"
     gene            35994..36956
                     /locus_tag="PC494_000946"
     CDS             35994..36956
                     /locus_tag="PC494_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HDF3911467.1"
                     /translation="MKKLMKHLALLLSLVMIFGLVGCSNGGDKEKNGEKKIAVLLPGS
                     TGYFVATKQGIDAKSKELGVSVEYADAQWDASKQLSQAEDFMAKGVDMIALCGVDSAV
                     SERIVKAANDSDVPIVAFTNSIGSNPTGEFKGLVTYIGQNEEETGALTGKIAKNLLGE
                     TGGKAVLIEGVPGTTPQVLRKKGLEKELKDSNIEIVYNQTSNWEKEQALKVTEDLIQK
                     KTDFNVIICQDDNSATGAGQALKDAGLKDKVKVIGLGGSKDGLKAITDGLIDGTTYMS
                     AVEEGGLVIEKASKFLKGEKIEPVTQIKQVEVNKDNISEFKGEW"
     gene            37328..37960
                     /locus_tag="PC494_000947"
     CDS             37328..37960
                     /locus_tag="PC494_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HDF3911468.1"
                     /translation="MARRLFLERIGLIFLGSAILAFGVYNFYYLNNITEGGVLGILLL
                     LKNLFNIQPAIANVVIDSLLLLVGYKFFGKKFLIYSIVASITFSVLYDLFEAIGPLVP
                     QSQNMLLSTILAGVTVGTGVGIVVKAGCASGGDDALALVISKTTSLNIGQVYLATDVI
                     VLLLSLFYLSAFDIFYSLIAVTISGKVIDFIYYHGKSLDMDISNDIVPEC"
     gene            38371..38463
                     /gene="kdpF"
                     /locus_tag="PC494_000948"
     CDS             38371..38463
                     /gene="kdpF"
                     /locus_tag="PC494_000948"
                     /EC_number="7.2.2.6"
                     /inference="COORDINATES: protein motif:HMM:TIGR02115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="K(+)-transporting ATPase subunit F"
                     /protein_id="HDF3911469.1"
                     /translation="MEGLPMWFLAVVIIMLIIYLVYALINPEKF"
     gene            38504..40186
                     /gene="kdpA"
                     /locus_tag="PC494_000949"
     CDS             38504..40186
                     /gene="kdpA"
                     /locus_tag="PC494_000949"
                     /EC_number="7.2.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015391009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium-transporting ATPase subunit KdpA"
                     /protein_id="HDF3911470.1"
                     /translation="MFMVQIVIVLAIFMILVIPMGKYLYHIATNQKTFGDRLFDKVDN
                     FIYKVCSIDKKKEMNWKQYALALLFTNAVMVFIGYIILRTQSMHIFNPSGIKSMEQGL
                     SFNTIISFMTNTNLQHYSGESGLSYFSQMTVIIYMMFTSAATGYAAAMAFVRGLVGKK
                     KTLGNFYVDLIRITTRVLLPGALIIGLILVTQGVPQTFAGTETVTTIEGKLQDIARGP
                     VAALESIKHLGTNGGGFFGSNSSHPFENPTIISNIVEILSMMILPGACVVAFGHMIKN
                     KKQGWVVFGAMSIIFLIGLVVCFKAESAGNPILSQLGLNQSMGSMEGKEVRFGIAQSS
                     LFTTVTTSFTTGTVNNMHDTLTPLGGLVPLLNMMLNVVFGGKGVGLMNMLMYAIIAVF
                     LCGLMVGRTPEFLTKKIEGKEMKLIALLIILHPLLILMFSGLSVAIPAGLEGISNPGF
                     HGLSQVLYEFASSAANNGSGFEGLGDNTMFWNITTGIVMFFGRYVSIIVLLAISSLLA
                     SKKAVNESIGTLRTDNFTFTIVLVLVVLIVGALTFFPALALGPISEHLVLWH"
     gene            40211..42268
                     /gene="kdpB"
                     /locus_tag="PC494_000950"
     CDS             40211..42268
                     /gene="kdpB"
                     /locus_tag="PC494_000950"
                     /EC_number="7.2.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010966942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium-transporting ATPase subunit KdpB"
                     /protein_id="HDF3911471.1"
                     /translation="METKKTKFITKDIFKTSIIEAFKKLNPKYMMKNPVMFVVEIGFI
                     VTLILTIVPSLFGDEGNNLRAYNGIVTIILFITVLFANFAEAVAEGRGKAQADTLKKT
                     RKDTVARVIDTLGNEKMISASELKLGDIVLVNAGEVIPNDGEVIEGIASVDESAITGE
                     SAPVMRESGGDFASVTGGTTVVSDWLKIRITTKPGESFLDKMIALVEGASRQKTPNEI
                     ALNTLLVGLTLIFMVVLISLYPMANYAGVKIPISTMIALLVCLIPTTIGGLLSAIGIA
                     GMDRVTRFNVIAMSGKAVEACGDVDTMILDKTGTITYGNRLASEFIAVGNADSKDLIN
                     YSVMCSLKDDTPEGKSIVDLGMKLGSTGKTKEAEEAEFVEFSAQTRMSGINLADGRAI
                     RKGAYDSIIKRVKESGGTVPEDLEENVNRVAKLGGTPLVVCVDNEIYGIIYLKDTVKS
                     GLVERFARLREIGIKTIMCTGDNPLTAATIAREAGVDGFIAECKPEDKIDAIKKEQLE
                     GKIVAMTGDGTNDAPALAQADVGLAMNSGTTSAKEAANMVDLDSDPTKILEVVEIGKQ
                     LLITRGALTTFSIANDVAKYFAIIPAIFTLAIPQMEILNVMKLSTSFSAILSALIFNA
                     IIIPCLIPLAMKGVKYRPMKSQAMLMRNMLIFGLGGVIVPFLGIKLIDLLITPLVMVL
                     NLG"
     gene            42287..42913
                     /locus_tag="PC494_000951"
     CDS             42287..42913
                     /locus_tag="PC494_000951"
                     /EC_number="7.2.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="K(+)-transporting ATPase subunit C"
                     /protein_id="HDF3911472.1"
                     /translation="MKTLKPALLVSIVLLVVCGLVYPLVLTGVSQVAFKDKANGSMIE
                     VNGVKVGSELIGQSFTDVRFFKGRVSSVNYNTYTKEDLVPDKDGNTSYGGVSSGSFNY
                     GATNPELHDRVQKDIEQFLKDNPTVKREDIPTDLLTASGSGLDPNISPASAKIQIPAI
                     AKASGISESKLQKIVDDNTSKKLFGVLGEDRVNVLKVNVEVAKILGLI"
     gene            43150..44058
                     /gene="cysK"
                     /locus_tag="PC494_000952"
     CDS             43150..44058
                     /gene="cysK"
                     /locus_tag="PC494_000952"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HDF3911473.1"
                     /translation="MLYNNALELIGNTPVVRLNNLGCTNGCSNIYVKLEKVNPAGSIK
                     DRAVYEMLEGLEQRGELKKGDVLVEATSGNTGIALSMIGKLKGYEVVIVMPETMSVER
                     RDLMKAYGANLVLTDGKAGMAGSIEKANELLKENPNYKSLKQFENKDNPNAHYKTTAV
                     EIMNDVKDLDIFVCGVGTGGTLIGTARYLKEQNPNIRVIALEPKKSPAISENKTGPHK
                     IQGIGANFVPENYDSSVVDEVILVDDEDAFDTVKLLAAKEGILVGISSGANIFGAIEM
                     AKKYPDKKIVTVAPDGVDKYMSMGIF"
     gene            44085..44675
                     /gene="cysE"
                     /locus_tag="PC494_000953"
     CDS             44085..44675
                     /gene="cysE"
                     /locus_tag="PC494_000953"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HDF3911474.1"
                     /translation="MFKKINKDIEYIMKNDPAARSKIEVFLLYPSVHAMIMHRMAHAL
                     YKKKKLFTARLISQISRFMTGIEIHPGAKMGEGILIDHGMGVVIGETAEVGNRVTIYQ
                     GATLGATGKDTGKRHPTVGDDVLIGAGTKILGPLNIGSNSKIGANSVVVKDVPNGATV
                     VGIPAKIVKIRNLEPVKKNKKEVSYEYDELDNVYYI"
     gene            44835..45023
                     /locus_tag="PC494_000954"
     CDS             44835..45023
                     /locus_tag="PC494_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HDF3911475.1"
                     /translation="MKANVNQDTCIGCGLCPSICPEVFDMKDDGKSHVIVDEVPSDAE
                     ESAAEARESCPVDAIDVH"
     gene            complement(45077..45946)
                     /locus_tag="PC494_000955"
     CDS             complement(45077..45946)
                     /locus_tag="PC494_000955"
                     /EC_number="3.4.11.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl aminopeptidase"
                     /protein_id="HDF3911476.1"
                     /translation="MKLNRNDSCWCGSTKKYKKCHMDMDNKIDSFAKLGHIVPTHDII
                     KNESQIEEIKKSAVINTKILDYISDKIEIGMSTEDINKLVHDFTLQNGAIPAPLDYNG
                     FPKSVCTSVNNEVCHGIPSKDIILKDGDIINVDVSTIFNGYYSDASRMFMIGNVNENA
                     KKLVQVTKECVQKGLEVAKPWGFLGDIGDAINSYAKKNGYSVVREIGGHGVGLSFHED
                     PFVSYVSKKGTKMLLVPGMIFTIEPMVNEGTHEIFVDEENNWTIYTKDGKLSAQWECM
                     VLVTETGVEILTE"
     gene            complement(46143..47387)
                     /locus_tag="PC494_000956"
     CDS             complement(46143..47387)
                     /locus_tag="PC494_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3911477.1"
                     /translation="MENNLNTAKRNNTELLQNDSLKVNLQIGVDFTLLSKSLKAFYKK
                     EKDFYCIALAPCNVSSEKANRKISIYDMIKEINILIESITDKNELLSEELFTNNLSEF
                     YDESLDEIYIDLKQAYLYIKKNTDSLNIEDSIEYVFDVDISNDIKAKENPLINFNSLS
                     LVVWSGETKHILQQMNILDLEDIHSYSIENNTNITIYENNTLQYKFNEESENIKDSSI
                     DIIEQMLILPDDLNYDKDEVENMKNRLAKINIKYLQTLKEKDIKIKLINSNLTDEPEF
                     SDLKYQLPPCWVRSGKTWKDVPGIYRNNSIVAKIGYSNPSYANVHSSKNLELHETAHA
                     IDKNVLNKKSNSEEFMEVFAQERYKLYDPKQVAHAYISKFIEEFFAESFVHYYLDEDS
                     KNTLKENCPLTYDFLEKLELNY"
     gene            47678..47989
                     /locus_tag="PC494_000957"
     CDS             47678..47989
                     /locus_tag="PC494_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HDF3911478.1"
                     /translation="MYFTYIIRCKDDSLYTGYTSNIVRRMNEHKLGINSKYTRAKGFE
                     KLEVYFVTNTKSNAMKLEYYIKKLTRNKKLSIIKNPSILINLIDNKEDYIIGKEIEQL
                     T"
     regulatory      48082..48174
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            48274..49068
                     /gene="thiD"
                     /locus_tag="PC494_000958"
     CDS             48274..49068
                     /gene="thiD"
                     /locus_tag="PC494_000958"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HDF3911479.1"
                     /translation="MSNYKIPTLTIAGSDSSGGAGIQADLKTFSAIGTYGMSVITAIT
                     AQNTKGVFAVEDLNKKIIKKQIEAVFEDIPPRAVKIGMVSSPEIILEIVENLKKYNPK
                     YLVVDPVMISKSGYYLLKPEAKENLIKYLIPLAYIITPNIPEAEEITGIKIHNVDDMK
                     RVGEEILQLGPKFVLMKGGHLDGEAVDILVGKNIFKVYKSERIDKKNTHGTGCTLSSA
                     ITSYLALGYEITEAVNLSKIYITEAIKRSFDIGHGVGPVHHFYKFE"
     gene            49092..49880
                     /gene="thiM"
                     /locus_tag="PC494_000959"
     CDS             49092..49880
                     /gene="thiM"
                     /locus_tag="PC494_000959"
                     /EC_number="2.7.1.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HDF3911480.1"
                     /translation="MYNLIKDVKKLNPLVIHYTNNVTINDCANVTLAVGASPLMSFSY
                     EEVEEMVSVANSVVINIGTMNSNMLDLFLLAGKAANKYNKPVVLDPVGVFASKARAEL
                     TSRLLNEVKFSVVKGNVSEIKFIGGFNVKGKGVDSFDEEEDSTEIIRKIAEKLECVVV
                     ATGKIDIITNGKGTYKINNGTDKLKGITGTGCMTASLIASFMAVTENILEAATMGVLT
                     MSLSGELANLNNPPIGTFKENLMNAIYQMDIDTLSKNSNIEFLN"
     gene            49903..50535
                     /gene="thiE"
                     /locus_tag="PC494_000960"
     CDS             49903..50535
                     /gene="thiE"
                     /locus_tag="PC494_000960"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HDF3911481.1"
                     /translation="MIDKESLKKCLKLYLVTDSEMLKGRDFYKCLEDAISSGITTVQL
                     REKNASGREFLRKAMKLREITKRYGVKFIINDRVDIALICDADGVHVGQSDIDVREVR
                     KLIGNNKILGVSARTLEEAICAKNDGADYLGVGSIFTTSTKLDAKSASFETVKEIKEK
                     VDMPFVLIGGINLDNIDKLKCLESDGYAIISAILKAEDISKEVEKWTLKI"
     gene            50674..50976
                     /locus_tag="PC494_000961"
     CDS             50674..50976
                     /locus_tag="PC494_000961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDF3911482.1"
                     /translation="MIRILLVCVGGMSSTLLVNKMEKDAKKRNIDCKIWAVGEGDIKS
                     ELDNFDILLLGPQLRFMLDDVKSIVGDRAPVSIIDMVNYGTCNGHAVLNSVLEILK"
     gene            complement(51042..51797)
                     /locus_tag="PC494_000962"
     CDS             complement(51042..51797)
                     /locus_tag="PC494_000962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF3911483.1"
                     /translation="MGMLNILWRSMKWRFKNPISFVVTILQPFLWLVLYSSIANQTMN
                     NININNYTAFILPGIIVLVVFSSCSSGGIINFIMKNSGSFYRVLIAPISRYSIVLGQL
                     LEAILVSFIEVTILCIVSIFFSVRIESGIGGILLMIVLIFMTAFFLSSLAYSISLLLP
                     NEIVYETIMTAIVLPIFFLSSALFPIESLSGGLKVAVMLNPFTHVINALRSLIFGETI
                     LIGDIMPVILLFLILCCSSFSLAMWRLKKEMVS"
     gene            complement(51785..52747)
                     /locus_tag="PC494_000963"
     CDS             complement(51785..52747)
                     /locus_tag="PC494_000963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF3911484.1"
                     /translation="MLAIEIDNLVKEYKNGVKALNALSFNVNAGEIFSLLGPNGAGKS
                     SLINILTTFYKPTSGNVTMFGKDLVDNPSWIRTQIACVAQQISIDEHLSLMENMVFQS
                     KMYKVEPQIAKQRIDSLIDKFDLSSYLKYPTSSYSGGVKRRLDIAMNMVSSPKILFLD
                     EPTVGMDVDSRKSMWDMLLKIRDEYGTTIFLTTHYLEEAEQLSDNICIMKNGKDLAQG
                     TPSSLRSYIRQNILRITFHNTEDIKKYKDAIKSTGLVKFMSVRENSIFISVNDSRTAF
                     TLINKWLLEHDIEFDAIEIVEPSLEDVFLALTSSKKSLKEEWEC"
     gene            complement(52751..53209)
                     /locus_tag="PC494_000964"
     CDS             complement(52751..53209)
                     /locus_tag="PC494_000964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HDF3911485.1"
                     /translation="MNCKIEIKNIESVTVATMRYNGPMTEATKYFPNVFKAIKGKSNG
                     APFFCYYDVDQKTGVAEMELCVPTAETPNRMGITTKEFPKTKALFFTHTGSYSNFPKT
                     YEMIFKYIHENNIKIQTPWREVFIKGPGMLIKGNPDNYITEIIFPLKEEE"
     gene            53564..53920
                     /locus_tag="PC494_000965"
     CDS             53564..53920
                     /locus_tag="PC494_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDF3911486.1"
                     /translation="MNFELDNTTPIYLQIVKYIKRQIVTGELKPGETIPSRREMALNL
                     KVNLNTVQRAYKEMGDMNIINTFKNYQSSVTVDENILKNLKLELINESLSVFIEDMKA
                     INVSKEEVLKIIEDKY"
     gene            53992..54708
                     /locus_tag="PC494_000966"
     CDS             53992..54708
                     /locus_tag="PC494_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF3911487.1"
                     /translation="MIEIKNVSKTYKRMQGLKIRKIEALKNVSFNIEKGKITALLGIN
                     GVGKSTMLKAIAGLINIDSGEIRIDGEKINEKVYNKLAFVPDVQSHFSNTTIKETFEF
                     MEIFYSKWNKEKSKEMMDIFKLDEDEIIDNLSKGNIARVKLILGFCQDPEYILLDEPF
                     TGIDLFKREEFIGVIAQYMEENQAIIITTHEIVEIESLVDEVVILDEGQIITSFNAEE
                     LREREGKSILDKMREVYKNE"
     gene            54701..55525
                     /locus_tag="PC494_000967"
     CDS             54701..55525
                     /locus_tag="PC494_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF3911488.1"
                     /translation="MNKLLYLINVDLRRSNKFYIAYISFFSLITLSLNLFEINKFKNS
                     KFIMNLAIEDFGGIFYGLGILSNLGFIQSILFFGILGLFIYYIFMWKREFFSNNQSIY
                     TLMMLPQNKFKICISKSIALITMIYGFLISQTATLFICKYIFNFIFRNMPIINMNFAK
                     DLYYLNLKSIPIDFISFMAIYVFLLLIAISIVNCCILFIFSYINKFYVILITLLIIAG
                     LYFSTIYINIITLFRKYYSLIGFQFNNLVAGLLSFLIIMFILNGISYLLIKKKVSL"
     gene            55537..56736
                     /locus_tag="PC494_000968"
     CDS             55537..56736
                     /locus_tag="PC494_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3911489.1"
                     /translation="MKLKSKISILIIFLTLAIYFSIGLLNNEDNLKIKTIKGDSNELD
                     HININFGYALNGYINSYYTINGSNKTKKTELIKLQKDSKNTNNLIDVSSGSDLIAHVG
                     FEMNEESKDINFVIDEKKEDLEKGVFPSEGSDKEIEYEKLDMNNFTRTRYKVDKSTDD
                     YYANILASKRYKKYLYVSVLYATSDSSENNKEYSSTIDIIKINPENKKIKTIKSINLS
                     NYFSEKYQNIETIGVSYASKYEDKMYILVNVLNTNIGDNSNSKFHLLEYNLEENKESI
                     MELKTDSKMALAKAKLEANKLYMVMSNDYDNSSITELNLLTYNILDKSLDEDKYVLDN
                     REKRGIRSIEIDSNKIVAYTSRLNSILSWDNKFMLYIINKNSKEIVYEGELQFNSSNS
                     MLEFEIK"
     gene            56745..57557
                     /locus_tag="PC494_000969"
     CDS             56745..57557
                     /locus_tag="PC494_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3911490.1"
                     /translation="MKDLIRLFEFELKRNIKNYIFIIICCCSFVILNIVKNLNDYNYI
                     IENAVKSEQLTKIGNTIETVKVTGFSSFRNIMGSTESWFMFGIIACICYAFFIWYRDF
                     NGRSKSIYTLIMLPKNRINIYISKLLNILFLVYSYTVVLTISLFIASKLLPRHMLGNV
                     TNYGFVQETIYELKMLLPYSFEILFVEYIFLLIGFVSVVFTSILINKSIYKVSTLISF
                     LFLVIEILVFIISIEFIIPYEYSDVFTVLYSSINIFVCSLISNKLLKQKIDF"
     gene            57568..58836
                     /locus_tag="PC494_000970"
     CDS             57568..58836
                     /locus_tag="PC494_000970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3911491.1"
                     /translation="MKAKNIGKYTICFIIVCFLMITMTLILSYFNKDKLSVKTLKGNV
                     KDIGRVSVVYTPNISKFSYEEVIISKNGVRNNTNPKSRIRNDYLNIDKKYSDFVNDKG
                     KEFIYKDDLNIGEAYTSVKSDLVQGMNALNDCIKVSNKNLKSGVEENFDINLNKSDFK
                     ENSWKTLFNKIYKGNLYMVISETNISGSKVNNICILKIDIKNKSYKLLNRFNLGLQNG
                     EQQNINEIKFSIGSKLYLEIVNNKSKNGYIEGHDSYSNFIIYDIEDNTFNISNKFMDN
                     LNKEKNANPKEIGLLSKTKLDYMVKNNKLNLIVTDMSNSITNLVYDINSNEIKLEDYE
                     ILDLKVDYNEASSGVRKVKLLDDKIYSISGIKNSISGELKGFKGIVDVVGTKPVKFQV
                     FDMKLKKNIYEAELINGDISLQEKLFFVAN"
     gene            59202..60383
                     /locus_tag="PC494_000971"
     CDS             59202..60383
                     /locus_tag="PC494_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HDF3911492.1"
                     /translation="MNKKYIKAGNLIDGTGNSIMQNKGIIIDGDTIVEIEDIRDDLNG
                     YDVYDYLDKTVMPGIMNCHVHLTMEPVGNPKIYYDNVSDVELVVNTIKQLDAYLDSGV
                     TYIRSLGCPKYVDVQLKNLIDKGSIDGPGIVTSGPVICMTGGHGYYFGIESDGVDECR
                     KSARTVLKNGVDCVKIMATGGVTTDGVEPGSPQLTLEEMKAAVDEAIKAGKITATHAQ
                     GRTGIKNAVLAGITSIEHGVYLDDEIIDLMLERGTYLVPTVAAPYFILNAGKESGITE
                     ATLRKCEIVAIPHKESFLKAYKKGIKIAVGSDAGTSYNEHGKTYYEMKLMSDYGMDNM
                     DIIVAATKTASELLRIDKNYGTLEKGKKADVIVVNGNPVENIDVLADVLAVFKLGKKV
                     R"
     gene            complement(60525..61442)
                     /locus_tag="PC494_000972"
     CDS             complement(60525..61442)
                     /locus_tag="PC494_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3911493.1"
                     /translation="MENNKCREDFRFTQEYEEDYPNTNERYYENYQVADRYYNYPNKY
                     KEPKIKQCCCKKSMREALELLRYDALRPFVNFNQFAFISDFFIVGANLVGIDLSAPPK
                     DNLSGLDGTFERFSACNCDLIDIAGRVSYPIPVPLTLEGLINTIGTIPGVAELIALID
                     AVIPPTIDLGAILDAILAAIIDFILAASTPLANVDLASLCNLKAVAFDITPADYEDFI
                     ASLGYYLDKKHYKECNCNCDCDDCCCNKGILDNLYMSNINNQVTVVAGSLVLTGVEVL
                     GKKNDVIVLGNSNDSRIYFVCVDSIDYIA"
     gene            61695..62489
                     /locus_tag="PC494_000973"
     CDS             61695..62489
                     /locus_tag="PC494_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF3911494.1"
                     /translation="MIEVDKLCKSFTRVVKDDKNKSSIRKLKKVKTKKEEFFAVNNVS
                     FKVMEGEIVGILGPNGAGKTTLLRMLGGILTPTSGSINISGYDYSIDRNSAKKEIGYL
                     SGNTKLYGRLSPRELLTTFASLYEMSKEDIEESIENIVKIMDMSEFIDNRIENLSTGQ
                     TQRTSIARCLIHSPKVYIFDEPTLGLDVLSSASIIDFMKNEKLRGKTVLYSTHYMEEA
                     ETLCDKIFMIHNGKIIASGTPQSLKEESGVNNLRDVFIKLARKEDI"
     gene            62490..64550
                     /locus_tag="PC494_000974"
     CDS             62490..64550
                     /locus_tag="PC494_000974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HDF3911495.1"
                     /translation="MRSKIVKYIFKKEMLDILRDKKTLFMMIVVPLLLYPLLMLLMIQ
                     VMNMSASSMNSKDINIAFNNKPNKVLVSMIEDDNLEKDTKNTSNDKGKIRVLDVDNYK
                     KSLEENKIDAYIKMEEKKSSINYQIYINSSQENSSNALKRIETVLDKYKRFTIEKTLS
                     EKGLDVQATLEPITYSTVDVAKTEEVAGYFLGQILPFILIIGVLLGSIYPAIDVMAGE
                     KERGTLETLFTLPISNLELVMGKYMAVSLSAIVTAILNILSMGLTMAFILVSGGISSQ
                     FGFGNFNYGDLVLPIITTLICICLFSMVVSAISMCVCSLAKSFKDAQNYITPLMLIIM
                     IPSYVSMIPNIVLDRVTAVIPVVNISLLIKSVLSFKSDLNLIALVLASNVAFVILAII
                     LLSKMFNSEEILFGNSKSFSFLEKRSNIKKGSIPTVSDGVILYAVGLVLLIYVGSLVQ
                     IKFGMAGIIMTQFMIISLPLLFAYYIKADFKEVFSLKVPKLKHVFGSIVLWIGGYILI
                     MIITQLILFLFPQNMEVAESLNKALFIKDSVLLNLLAIALLPALCEEMFFRGFIFSSF
                     SKSKDKNKSIKLAIICSGVLFGIMHMDFIRIIPTSILGIIFAYSVYKSGSIFVSMLLH
                     FLNNSVAVVLNHYTTGNITNLYKFVEVDFSNLNVLKFALILLISLILIMLGLRVLDRK
                     SLRN"
BASE COUNT        24719 a         7235 c        11265 g        21507 t
ORIGIN      
        1 tattagtttg ttgtagctaa taaaaactga aaattctaaa attataattg taagattata
       61 taaatttaga atttaaatct gttgaataat attaaaacaa tgataatgag tatgaatttc
      121 taataaaaat aaatatcata aaaataagaa aaagtattgg gaggaaatga aaatggcaag
      181 aatgtattat gaaaaagatg tggatttaga agttttaaaa aataaaaagg ttgcagtttt
      241 aggttatgga agtcaaggac atgcacatgc acaaaatctt agagataacg gtgtacatgt
      301 agtgataggt ctttatgacg gaagtaaatc agcacaaaaa gcaaaagaag atggatttga
      361 agttaagagt gtagcagaag ctacaaaaga aagtgatttg acaatgatgt taatgcctga
      421 tgaaaaacaa aagaaagttt atgaagagag tgtaaaggat aacttaaaag aaggccagac
      481 attagctttt gctcatggat tcaatataca ttataatcaa gtacaaccac cagaatttgt
      541 tgatgttgta atggtagctc ctaaaggacc tggtcactta gttagaaatg tatttacaaa
      601 gggaagtgga gttcctgcac tatttgcagt atatcaagac tacactaaaa aagctacaga
      661 gacagtttta gcatatgcaa aagggatagg agcaacaaga gcaggtgttt tagaaactac
      721 ttttaaagaa gaaacagaaa cagatttatt tggagaacaa tcagtacttt gtggtggaat
      781 aagtgaactt ataaaattgg gatataaaac gcttgtagat gcaggttatc aaaaagaagt
      841 agcatatttt gaatgtttac atgaaatgaa actaatagtc gaccttatat atgaaggtgg
      901 atttgaaaga atgagatata gtataagtga cacagcagaa tatggagatt atgtatctgg
      961 taaaagggta ataactgatg ttgcaaaaca aggtatgcaa aatgttttag aggatataca
     1021 aaatggaaaa tttgcaaaag cgtggattaa agaaaatgaa gaaggacgtg aaaacttcct
     1081 aaaaactaga gaagaagaat ataatacaga aattgccgaa gttggtagaa atctaagaag
     1141 tatgatgtca ttcttaaaat aaatatatat taaatggatt agtttgaggg aaagagtggt
     1201 gtatagtagt gcgtatgaat ggagcaaagg taattttaga atgtttaaag aaagagggaa
     1261 ttgacacaat atttggatat cctggtggag ccgtgatacc tctttatgat gctctatacg
     1321 attattcaga tgattttaaa catataagga catcccatga acaaggttta gttcatgctg
     1381 cagatgggta cgcaagaagt actaatacag taggagtttg ttttacaaca tctggtccag
     1441 gagcaacaaa tgccataact ggaatagcaa cagcttttat ggattcttca cctatggttg
     1501 taatttcagg gcaggtgcca actagtttat taggaaaaga ttcttttcaa gaaattgaca
     1561 taactggagc aacattatct atgacaaaac ataattattt agttagaaac actaaagaat
     1621 tagttcctac aataaaagaa gcttttagag ttgcaaattc aggtagaaaa ggacctgtac
     1681 ttgtagatgt tccaaaagat ttatttttag cagaaatgga ttttagtggt gaggactatg
     1741 atttatgtca aatagatgat tatatggatt ataagagtga ttttgatcta gatgatgaaa
     1801 ctaatattaa gcttttaaat gaagcaatag atatcataaa agaatctaaa aagcctataa
     1861 tatatgcagg tggaggtgtt aaatcttcag acagtgagga aattcttgaa aaatttgcaa
     1921 ctaagataga tacacccgta ctaaatacac ttatggggct tggaaatata gatagaaaga
     1981 atgaattatc tcttggaatg gttggaatgc atggaagtag agaaagtaat ttagcacttt
     2041 ctaattcaga tttagtaata gcgataggtg cgagatttag tgatagagtg ataagtaaaa
     2101 gttctgaatt tgctaaaaat gcaaaaataa tacacataga catagaccca tctgaaataa
     2161 gtaaaaatat agaatctaat gtatctttgg ttggagatgt aaagctagtc cttagtttat
     2221 taattgaaag ggttgaaagt aagaataata gcaattggaa agaagagata aagagattta
     2281 gaaagagtga gggtgtacaa acatatgaat ttcatccaca aaatatactt aaaaaaataa
     2341 atgaaaaata tgaaacatta aagaaaccca ctgtggtagt aactgatgtc ggtcaacatc
     2401 aaatgtgggc tgctaagtac tggaatttta aaggtaataa aagttttata acatcagcag
     2461 ggttaggaac tatgggattt ggtttaggtg cagctattgg aactaaagtt ggtaatgtag
     2521 ataaaaatgt ggttttagtc actggtgatg gaagttttag aatgaactgt aatgaactag
     2581 ctacagttgc aaattataat gtacctatgc ttattttact actcaataat agaacattag
     2641 gaatggtaag gcaatggcaa aagttatttt ccaatcaaag atactctcaa actgacatta
     2701 atgaaaatgt ggattatgtt aaactcgtaa atgcatataa cattgatgga tataaggtat
     2761 ccagtatgga agaattagga aaggcgctag atatgataga ttttaataaa ccagtatttt
     2821 tgcaatgtga tatagataag gattatgatg tttatcctat tgtagcacct aatgatgcat
     2881 tggaaaattt gatatgtaac taaaacttat actgaatatt gataaaattt tttattaaat
     2941 ttttattagt attcagtttt tgttgtttag agatagattg gcatttttta tttttgcaaa
     3001 taaatcaatg actatataat taagaactta ttaaatttta attatacaat ttagaatagt
     3061 attacaactt aagtaaataa taattttgaa taataattta cggaggtatt catatgttta
     3121 aacacgataa agcattatta aaagaagtaa aagtagaaag accaaatcct caatatgctg
     3181 ttttaatgca agaacagttg ggtggtgcaa atggagagtt aaaagcagct atgcaatact
     3241 tgtcccaaag ttttagaata aaagaccctc aaataaaaga tttatttctt gatatagcag
     3301 cagaagagct tagccatatg gaaatggtag cacaaactat aaatttatta aatggacatg
     3361 atgttgatta taatgcagtt aatacaggcg aaatagaaac acatgtatta actggtctat
     3421 caccagtctt aataaactca tcaggagctc cttggactgc taattacgtt acagttacag
     3481 gggatttagt agctgactta ctttcaaata tagcttctga acaaagagct aaggtagttt
     3541 atgagtactt gtatagacaa atagatgata aatatgtaaa agaaacaata gatttcttac
     3601 ttaatagaga agaagcacat aatgctctat ttagagatgc tttaaataaa gttaaagata
     3661 caggttcaaa tagagatttt ggagttacag aagattctaa attatatttc gatttgtcta
     3721 ctccagggcc aaatcacgat actaagatag atattaatcc tccttctttt gaaaaacctt
     3781 taaaaaaata atttgatatt ttttatgttg ttttgtttta gtagttataa aaattattta
     3841 ctagaagaat taattatatg aaaaattaaa tatgtatagt taaaaatggg tatacactta
     3901 ttataagtgt atatctattt gtttattgca aaacatataa taaaataaca aatgaggtgg
     3961 tattttggac agtaatagaa aacctaataa cctaataaat gaaaaatctc catatctttt
     4021 acagcatgct tataatccta taaactggta tagttggaat gatgaggctt ttaaaaaagc
     4081 aaaagaagag gataaaccaa tatttttaag tgtaggatat tcaacatgtc attggtgcca
     4141 tgttatggaa aaagaatctt ttgaagatga agaagttgct gaaataatga atagaaactt
     4201 tgtggcaata aaagtagata aagaggaaag acctgatgta gatagcgtgt atatgacagt
     4261 ttgccaagct atgacaggta gtggtggatg gccaatgacc ataataatga caccagataa
     4321 aaaacctttt tttgcgggaa catatttccc aaaatattca aggtataata ggcctggagt
     4381 tatagattta ttagagaatg tatctgaaaa gtggaataca agcagggata tattaataaa
     4441 atctggagat gaaataatag aagctcttaa ggatgatttt ggtgtaaaaa atactgaggg
     4501 tgatttatca aaagagatgt tgagttcatc agttagagta tttaaggcta tttatgatga
     4561 aaagtatggt ggttttggta atgctcctaa atttccaagt cctcagaatc ttatgttttt
     4621 aatgaaatat tatagtatag aaaaagacaa agatgtgtta aaaatggtgg aaaaaacttt
     4681 agatggaatg tatagaggag gcttgtttga tcatattgga tttgggtttt caagatactc
     4741 tactgataaa aagtggttgg ctcctcattt tgaaaaaatg ctatatgata atgctatgct
     4801 tactatagct tttttagatg cgtataaaat aacaaagaaa gagttgtata aagaaattgc
     4861 tataaaaact atagattatg tagttagaga gatgaaggat aaagaaggtg ggttttattc
     4921 agcacaggat gctgatagtg aaggtgaaga aggtaaattt tatacattta atcctcttga
     4981 gataattgaa gttttgggtg aagaagatgg aactttcttt aataattatt ttgatataac
     5041 tagtagtgga aattttgaag gcaaaagtat tcctaatctt ataaaaaata aagaatatga
     5101 gagacataat gaaaagatag ctgaccttag taaaaaggta tttgaatata gaaaagaaag
     5161 aacatctttg cataaagatg acaagatact tacatcatgg aatgcattga tgatagttgc
     5221 tttaacaaag gcatatagta ctttaaaaaa tgacatatat ttagagtatt caaataagtg
     5281 tcttaacttt ataaataata atcttgtaaa tgagtcaggt agattattag ctagatatag
     5341 agatggaagt tccgactatt tagcatattt agatgattat gcttttttaa tctgggcgta
     5401 tatagagctt tatgagtcaa catttaatat gaaatattta gaaaaggctt taaatttgaa
     5461 tgaaagctgt atcaaccttt tttgggatta tgaaaaaagt ggattttata tatatggtaa
     5521 agatagtgaa aatttaatag caagaccaaa agatttgtat gatggagcta ttccatcagg
     5581 aaattctgtt caattataca atcttataag acttgcgaaa attactggag ataatagact
     5641 tgaagaaatg tcatataaac aattaaaact gtatgtggat aatgtaaaga gttctccaac
     5701 tggctacagc ttttatatgc tttcattgat gtttgaactt tattctacta aggaaattat
     5761 atgtattttt aaggaagatt ctgatttaat tgcatttaaa gaattgataa gtgaaaattt
     5821 tataccaaat gcaacttttt tagcaaagaa atacaatgaa gaaaacacta ttataggttt
     5881 tttaaataac tatagattga aggatgataa gattagttat tacgtgtgtc aaagtaatag
     5941 ttgtagtcaa ccaattaatg atttacaaaa attaaaagat atgattttag gagtagaata
     6001 atcataatag cgaaaaagga gatgctttaa aataaaagtc taatcatctc ctttttttgt
     6061 acaaaaaaca gaaaaagagt tcctaagaac acctaatcta tgtaatgatt gttttgttaa
     6121 aaaataaaaa tgacattata gttatataaa atattgtact ataaaaaagt ggtattatag
     6181 atgcgatagt attaatcttt tttatttact ctatttcttc tttttgcaaa ttcttcaagt
     6241 gcttcagatt taattttatc tatttcttca tattccataa aattagcatc ttcttcaaag
     6301 ccatcttgtt cttcaccatt aaaacgatac atttttttta gtaaactcca taaggtctct
     6361 aattcatctt tggtaaattc gtgaaataca tctgccataa agtttattcc agtcctacta
     6421 catgtcacca taaccttttt tcctaagtct gtaactttaa cattaattgc tctcttatca
     6481 tgaggacttg gaattacatc aacatatcca tttttttcaa gattagcaac tagtctattt
     6541 atattttgtt tacttgtacc catttttctt gcaatattat ttaatgttgt ttcttcctct
     6601 ggtaaatgaa gaattgataa aatagtcata tactgtcttg aagtaagtat accaaaatat
     6661 ttatctcctt ctatttgtat tttgtttgta agggtaaaaa gagttgcata tgtttgattc
     6721 attaaaaaga gctcttttag ttcatttgaa taatccatga aatatatctc ctttattttt
     6781 agatgttgtt ttgtcgaaaa cagaatatca tgaattaatt ctaatgtcaa tatggtgtca
     6841 aaatatatta aagtattact tttttatgta actattaatt aagagataaa ttatatatgt
     6901 ctttttgact atctttttat atcttcttaa atgtccgcaa agccttattt tataggctct
     6961 acgggcattt ttcttttgtg gtaaacctca catatctagg tctatcttct tatattttcg
     7021 ctatcaagcg tggttaaaat cgtggtaaat acttctatgc gattagacgc tgaacctctg
     7081 attttgcagt atctatggac gcatgagcat accagttcat tgtgatactg atatttgaat
     7141 gtcccatgat atactgtaaa tcttttgggt tcatgttctt gcttgccagc cttgtgcaga
     7201 acgtatggcg tagcgtatgc ggtgtgatat gtggcaaggg gttatcctta tggtgcttgt
     7261 tgtatttctt taccatacgg acaaataagg cgttataatc aatggcaact ttgggcttgc
     7321 ctttctgatt gacaaataga aagttgcccc gtccgtctat cacaaatggt tctgcctttg
     7381 ggcgtttctt catcactcgt tgaaatgctt gtatcgtttc tttgcttaat ggcacttgcc
     7441 ttgttccact ctttgtctta ggcgtttcaa tataatagcc ctgttccttg ctctttaata
     7501 actggtggtc gataatcaca acctcattct tgaaatcaat gtcggctact gtcagtccgc
     7561 acagttccga gatacgaagt cctgttttta acagtatcag cacatcatca taatacttgt
     7621 gatacacgtt gtccgtcttg atgaatgaca gtagggcttg ttcctgttcc tctgtcaatg
     7681 cgactttctc tttggtatca ttttctagga cttcactcaa cttgaaatca aaagggttct
     7741 tccttacaca atcgtcttgt atggcgatat agaatgacgc ttttaacgag cgtttatggt
     7801 tgttaatggt gttataggaa aagcctttgt ctttcatgcg taacgcccat tccttagcgt
     7861 cagagggttt tatcgtatca atgctcctag cacctaactt gtcctctttc aataaccgca
     7921 tgagctgttc ccgttgtttc tgtgtgcttt tcttcacatt tgccctctgt gtgttctgtt
     7981 tggcataaag ttggcaaagt gtcattttct tgcctgtgct gtcgataccg tcctcaatat
     8041 cccgtcttat ctgctgttcc agttcacgaa gtgagggttt ttcccgtttt ccctttggtg
     8101 tcgggtctgt gggtgtcaat ctccaagcat acacatattt tgtgttccca aatgcgtcca
     8161 catatttata taagtatttc ccgtctgttc gttggctctc tccagtatgc aggatacgtc
     8221 ctttgctatc ccgtcttttt tctttcatgg tgtctgctcc tttccttgtt ggaaagagcc
     8281 ttgatatgac ttgtgttcat cataacacat acaaggctca tttgcattag attgcgtcca
     8341 atttatcaat aacctgttca aactgtcggc gtttaatctg tatgcggttg ccattcataa
     8401 tgagccagcc agcgtccttg ttttcctctg ccaagcgtct taacttgttt tctccgatac
     8461 ggaaatactt tgatgcttct tcaatggtaa gggtgtattt ttcccatacg ggaatatcgt
     8521 tgttattcat cagatacccc ctttcccatg tttggtgtca tactggatat aggggataag
     8581 gtcggtgcgg tttatcctct gtaaatgggc ggttaattta ctggaaaggg aattgctgta
     8641 tcttgcctta tcaagcatag ttcccacttt ttccagtcca cctaatgcgt tatgttcttc
     8701 caagaagtaa aaacttttga cagcggaaat cacgccaccc tctgtgagcc actgctgtgt
     8761 ttcctcaagg gaattttgtt gttttggtac ttgcagtttt aagacttcca cagcccctaa
     8821 aaagcgttcc caaaaccgac acgttttcca tctgctctta ttactttcgt ttctgtttgg
     8881 tacgacaaag cgtaggttat ttgccaatag tccgaaagcc agttctccaa gttccagcgg
     8941 tctgtccttg aatgtcatgg caaaggcatg agccttatca tcacgcagtt gcatttctgt
     9001 ccgtttccaa ctgccgactt catcaagcgt cttattatgt tttgaacaga cttccttatc
     9061 cttgtcataa aagcggtagg acaatcccga tttaccagca ccgatataaa cagtctttgc
     9121 ggtgtcgaaa tcatcaaact tgctttcgtc aaagtgatag ccctcactat tcgagataaa
     9181 ttcctccttt tcgcatttct tctttatctg ctctatggta aagaatggct tttcgttctt
     9241 atcatcaatg gcaatatcaa gtcttgtgaa atggaaatta tccagtccgt atcttcgctc
     9301 acagcgtcgg aacatatccc caaaggtata attcctactg tcgagaatac ggaaaatatc
     9361 atcacaacct ctgccggtca taacaagata acagcctaac ccttgtgggt tatcctctgt
     9421 ctttcttgcg tcccccgata cataaatatc tccaatctgc cagcgtgctt gataggtttt
     9481 gtatttaacg cttgccggat aaacattgaa aatgtcagtc ggtaaaccta aaatgtgcat
     9541 gatgacatct tcggcggttg cagtatcgaa tacaatactg atgtaatcaa tcttaacgga
     9601 taaatttttg tgtgtagtta tagtgcatta ctcctttcgt acttcccgtt tttttgcggg
     9661 gtaaaaatcg tgttttttcc tttatttatc acagtttcta ggtactatga catgtatgcg
     9721 cagggcggtg ttacatatac gccctttacg aacgcctaac ggcgttccct ttccaaaagg
     9781 aactgtctgt ccgaacacgt ctgggggacg tgccccgtcc agccagcccc ttttggaaac
     9841 cactattttc ggtctgatag tccatgctta ttcatgctat caaaatgaaa atacatcttt
     9901 cctatgctta ctcaagcgtg tgattgaccc tagcgtgctt aatcacccta tctaatacga
     9961 taataacgct attagaatta cttgtcaaga agtttttgtt gacttttaga tatatattaa
    10021 gtatgatatg cttataaata ctaagaaaag caacgaaagg agcggttata ctaagttatg
    10081 gagcattacg aaaagaaaat cagtttctta ggagaaaaca tacagaccat aagaaaacac
    10141 aggggaatga aacaacagga acttgcggac aaaatcggta tcaatatgca gagcctttcc
    10201 aaaattgaac gaggtgtgaa ttatcctacc tttgatacgt tagagaagat aatggacgtg
    10261 ctgggtgtaa cgcccaatga attattgtcg ggagaatgga agtatattga ccacaccgag
    10321 ccatatatca tggatattat caaacgggaa caagacttca atgtttcctt agattatctg
    10381 tctgaaaatg aatttttcaa tgacgaaaaa gaatgtagat tttacaagga atataaactc
    10441 atacagtata ttcataacta cattaccaat gaggttacgg agttggaaga acttatggaa
    10501 atcaagcagt taatacaacg tcaaaaaata gaacgcatga tgaaagtaca taaggaaatg
    10561 cgagggttag accgatacag agaacagccc aaagagtata aataccatga cccttatgat
    10621 gattggatat tccgtcagct tgcagatata gataacagaa acaacattcc cgacacttct
    10681 ccgcaattag atttcaatga ggcggactat gaagattatc taaaggcaaa atggaacaga
    10741 ggtctttaat ttcctcttgc atggaagata cagtaaacaa aaagcccagt aaagagtgca
    10801 aagcaccacc aatggtggca aggctcttga cagggctttt ccttttctgt ggtgggtaat
    10861 caagaggaag aaagaaaaag tgtgtagtcc aatgcagaaa atatttaaag ggtatgttga
    10921 tttttgttgt gatggatata tggaactgct ataatatggt tatgaagaaa aagataaatt
    10981 aaaaattcaa ggagaaacta aaatgattgt attttggata atcggaattt tgtttttaat
    11041 cgtaggctta atagttagtg ttcctacaat tattaaattc atcaaatgca aggaacatac
    11101 aacgggtaaa attgtaagta ttgatagttc atcaaatgga tatgccagag cagtatatga
    11161 atatattgta tctagcagca aatatacaaa taaaacaaac tggactccac atcatatatt
    11221 tcatcttgat ggagagtgtc atgttattta tgataagaat aatccaaatt cttcttatat
    11281 caagaaaagt ggacaatata ttcgttgtat tgtaggtata ctttttgcaa tgattggaat
    11341 aggtgtattg ttactgggga tatttcttat tactgtttta tagcggtaca atgctttttg
    11401 ctttgatgat tttttagaaa gtgcgaggta cttatttatg aaaaagaaaa attttttatt
    11461 tatagttgca atgctttaat gaggcagact atgaagatta tctaaaggcg aaatggaaca
    11521 gaggtcttta atttcctctt gcatggaaga tacagcaaat aaaaagccca gtaaagagtg
    11581 caaagcacca ccaatggtgg caaggctctt gacagggctt tttcttttct gttgtagggt
    11641 aatcaagagg agaaagaaaa agtgtgcatt tttgttccat agaaaaatgc taagggtatg
    11701 ctgattttta ttgtggcgga tatatggaac tgttataata tggatatgga gaaatggaca
    11761 aagtagaatt taacacgaac aagatttaat tataggagtg tactcaatgt ggcttttagg
    11821 gagtattttt atattcacat cactattaat tctatacata aaatataggg ttgtttttac
    11881 tggcgaaaaa tgcaaaggga aaataatcga cattgtagaa caaaatgcag gttatgtagt
    11941 aggtggtgtt aatgtcaaaa agcatgctta tatagtgaag attaaaaaca aaaaatatca
    12001 tactgcacat ggttgtatct ttttgtcatt gggaaagaga aatattggaa aagaaatttc
    12061 cgtatttaag aatgaaaaat atggaaatga ggttttcaaa tgctttgatt ttcgtataga
    12121 gattgttgct ttgttagtat ttttatttgg cgtttttatg atctactcag ccttatgata
    12181 aagccaagca ggtttcagtt tgaaaagaag ttatacgcaa agaaaaattt agaagttatg
    12241 gaggaaacca tatggaaaat ttaagtgcat atagatactg tatcgctatg aaaaaaggtc
    12301 gaaaaatatt aaatctgatt gtgggctgct taatgattct tataagtatc attttcataa
    12361 ccacaactgt ttttagctgt atttttatgc aggaatttgt ttattacaca tttttagcaa
    12421 tattccttat aattataccc ctacctcttt ttatttttgg aattataggt attgtctcag
    12481 ctacaaaacg agttgaagtt tataaaggaa aagtgattta tcatattggt tttaaaaata
    12541 aggaatatcg tatgtctgat attaaaacat caaaaacaaa aagtgaaaca tatagaacag
    12601 gattagatta tggaaatatt gtacccacct acagttatga taaattaact gtattctatg
    12661 ataaaaaagg gaaaaagatt tttaaatttg gattggcata cgataatgta gaacgactga
    12721 aagcagatgt taataatact caaaaaagca tagcaaaaca gcataacaag aactaaataa
    12781 atttcagttt gaaaatggga aatgaaaaag tggcaatttc aaatataaat acaattatta
    12841 gtaatgatat tcaaaaagtt tggaacattg ttttagctgt tgataaatat aactcatggc
    12901 gaagtgattt gagcaaaaca gaaatagact ttacagaaaa tgtgatacct aaaaagtgtt
    12961 ttatgaaacc ttttgtaaaa acctatttga aaaaacaaca aaagcaattt gttctggact
    13021 taaagaaagc attggaataa taaaattcaa gattggagat ttagaaatgg cttcaagtaa
    13081 agattattta caatttgttt tagaacaatt atcagaatta caagaaataa catatcgtgc
    13141 aatgatggga gaatttatta tctattatcg tggaaaaatc gttggcggta tatatgatga
    13201 taggttgctg gtaaaaccaa caaagtccgc aatttcttat atgccagcag ttacttatga
    13261 aattccatac gaaaatgcta aagaaatgtt attggtggaa gaaattgata ataaagattt
    13321 tctgatgggg ttatttaatg tgatgtatga tgaactacca acgccaaaac ctaaaaagaa
    13381 aaaataaaca gtttttagtt tgacaatttc atatccatac acacaaagca gttagtcttt
    13441 atgattgact gctttttaac aaaagacacc gcttaggtgt taagggtgtc ttttagagct
    13501 attttattgt catatcaagg ctcactcaat cgtggtaaat tcgtggtaaa ttgaatgatt
    13561 ttctatactt caaattgctt gaaagtatag tgtttatgtg gataatcgaa aattatatat
    13621 aaaatttaat taaattattg tataatttta tgtaaaaact tctatgtacc aatgataact
    13681 tctatgagga attaataatt cttaaatttt ttagaaagat tttgacttga aaatacttgt
    13741 aatataatat ataaattaat atactgaata aaatcaatct ggagggataa ttatgaagtg
    13801 tacaaacttt actttcaaag gagaggaagg tttagatata tatacatata aatgggaaga
    13861 tgaaaatata aaaaaaccaa aggcagttat ccaaattgca catggaatgg ctgaaactgc
    13921 acaaaggtat gagacttttg ccaaggtact tactaaaaat ggttatatag tatatatcaa
    13981 tgaccataga ggtcatggga aaactgcaaa gataatagaa aatgttggac atttagctga
    14041 aaaagaagga tttagatgtc ttgtagagga catgtatact ttaacaaata ttataaagaa
    14101 agaaaatgaa gatctgccaa tttatctatt tggacacagc atgggttcat ttgcaagtca
    14161 aagatatata atggattaca gtaataattt atctggtctt atactatgtg gttcaaatgg
    14221 aaagcaagga atcattctaa atcttgctca tctgataatc aatcgtgaga ttaaaaagta
    14281 tggaagacgt tctaaaagta ataaaataaa taatttgata tttggcggcg aaataataag
    14341 aagaaatgaa aagactaagt ttgactggtt aagtagagat aaagaacaag ttgaaaaata
    14401 tataaatgac ccattttgtg gagtagtgtg tagttgtggc tttttttatg atttagttca
    14461 agggttaaaa gaaattgagg ataaagaaaa cttaaaaaaa gtgccacttg atatacctat
    14521 ttacataata tctggagata aagaccccat aggaaaaaat ggtaaaggag tcttaagact
    14581 aagggataga tatataaaat taggagtaaa agatgtaact tgcaaacttt acaaagatgg
    14641 aaggcatgaa ttgttgaatg aaataaatag agaagaagtt tttgaggata taatttgttg
    14701 gttaaataat aaaatagaaa tattgtaata aaaaaatata atgatatatt tgctttaaat
    14761 ttatttatat ataatatttg aaaagtggat tatgtatatg caaagtagaa aagagagccc
    14821 agaagtgatt ttttgctata atgccattta ttgaataggt gggtgttatt ataaataaat
    14881 tattaacact cagtattatt atcattgtat atggaattta ttttatttaa aattccttga
    14941 aagtttaaaa gtttaaatat agtaagttgt aataaagaga aaatctaaat atttaaatgc
    15001 tatttaatgt gaatctatta attaggttat acttaaactt aattaataga ttttatattt
    15061 caagccaatg agatagggtt ttagattaaa atataaccaa tggttaaatt acagacattt
    15121 tgttaacttt ccctcgattt actagtaaat atttttttta tatacttaaa ttacaacaga
    15181 tgtactaggg aggtatatat gcaaattaaa ataggtaaag tcatacagtg tcttagaaaa
    15241 gaacgaaatt taactcaaga acaattagca aagtttatag gtgtgtcaac accagcagta
    15301 tctaagtggg agagtggaaa ttcttaccca gatatagaat tattgccttt attagcagac
    15361 ttttttaatg tgtctattga taagctttta aattacaaga ttgatttaag tgaagaagaa
    15421 gtaatgaaaa tttataaaga attagaatca ggctttgcta gaattgaaat tgatttatca
    15481 acagaagaac caaaagaaga atttagacaa gatttagaat ctgtaaaaaa gctttccaat
    15541 atgtatatag agaagtatcc taaaagctat ttattgaagc taaggatatg ttcgctgtat
    15601 cagatgtatt catataaatt tggtaagagt gaacttaatg acagagtaaa agaaacaacg
    15661 aatattcttg aagatatagt gagaaataca gatgatatcc aaataaaaga aacagctctt
    15721 attatattat caaacgcata ttgtatgttg gaggattatg aaaaggcaga gttgtattta
    15781 aatatgatac ataagtcaat aggggataca agtgttaatt tagctatgat atatttaaag
    15841 caaaatagac ttgaagaagc agaaatattg cttcaaaata aattgtttag taatgtattt
    15901 aatataagca tggattgtaa gggaataatt aatgtataca aaaatcaata caaggaatta
    15961 aagaaaaaat tggagaatag aaattttaat aaaaatgcaa ttgagagaga aatggagtat
    16021 ataaaaaata agttgctggg gtatgcaaat ctttctttag aaataaaaaa aatgctcagt
    16081 gaagataaag gtgcattttt tagtatgtat atggattata tggaattatc tctaattttt
    16141 ttatttttta acatgaaaga agaagcaaaa aaagctttat atagtctaaa agaaatatta
    16201 gaaaaatatc ctatacatga aagtttggat gtaagtcaaa tgagattttt tgataaggta
    16261 gagtctaaaa atttatatac ttttaatata tatacaaact tgttaattgt acttaatgat
    16321 gacagttata atgagcttag agaagaacca atttttaagg atgtaattga aaagatttta
    16381 gatatggaaa aaatgttgaa aaataaagaa taagtaaaaa tttaatatag gacttaaaga
    16441 ttaatcaaat taaaagaaag tgtttcaaaa taaaaatttg aatcaccttt tttgtcggtc
    16501 ttaaacagtt atttagaaaa atagaggttt caaaatagaa atctgaatta tctgtattat
    16561 tacacaaaaa tagaaaccta aatttataaa aatagaataa agtttgttat ataaaatgta
    16621 attttgtcta taaaatctca cctgttttct taactttaag cgtgaaaaag aggatgtatc
    16681 atgaattttt tagttcatga tgcatcctgc tttgtatgaa atccaatata tctttattat
    16741 ttaaacaatg gaaaagagtc ttatttatat ttggagacat ctcttttatt taattatgaa
    16801 gttttataca gttcaataaa taggaattat atttagaaac tcatgacatt atttcttaga
    16861 tagtgattaa atttatcata ttccatttta gataactttt ctgggtaaga cattacaatc
    16921 aggttatgcc cattaaattt tttatggtat ggtggatgaa tgtgttcata attatttgtc
    16981 ttatatttta ctctttcata gaacgccttg cgataaattg aaatctcatc aattggaagg
    17041 tcaatttcta agataatagt ttttcctttc ttatttaaaa gctctaacgc tctttgccca
    17101 tatctattat tgcgcatttc tggaaaaatg cagaaatgtt ctacatagat aaagtcatct
    17161 gtttcccaac ataaaattat gccgacaaac tggtttttat cataaattaa attgaattga
    17221 tattctttat ttttcaaaat ttctgcttgc aaagaagatt ttctttgttc atgaaatggg
    17281 aaactaattt tatataattc catagccttg taatataatt tattttcact ggttcttaac
    17341 cattcaaatt tcactttact cctcctaatc acgaaaattc caatttattt atgagttcat
    17401 tttaccatag tcagtatttg catacaatgt gttttaagtt gagtgtcatt tctttctttt
    17461 atttatgctt atatctcata gtctaagaga taattgctta agacataact aaaaactatt
    17521 atattaagct ttgataatct aaaaacagta tatttatgga cttttctagg tctaaaagta
    17581 atcttaataa ttttagaagt tacaaaaaag ttacataaat ttggaaagct ataatataca
    17641 tatataatat aaggttaaaa ctgtaatgaa taatattaat ttaaaatttg aacatggaag
    17701 gagattatta tggagaaaag agaaaagagg ataataatat catctttatt aagtgtatca
    17761 attttaatgg ggttggtaag tatatattct atattaaata aagaagacat aattttaact
    17821 gttaagggtc aagagcaaaa agtatcttcc tttaagaaaa cagttgagga acttttggat
    17881 gaacagggtg taaagtataa ttctgaagat aagattaatc caagtttaga tacagaacta
    17941 aaagatgata tgaaaataaa agttgttaag gtaactaaaa gtaaaaaaga agagattgaa
    18001 aaaattccat ttgatacaaa gcatgtaaat gatagtaatt tgttaaaagg aaaatctaaa
    18061 gtttatcaag aaggtcaaga aggagaaaaa aaactagtct ataatttaac ttaccatgat
    18121 ggaaagttag tcaaaaaagt cttatcaaaa gaagtaatat ctaaggagcc aactacaaaa
    18181 attataaaat atggaactaa agaaaaagta ctaatagcat caagaggagc aaatataaga
    18241 ggaggcaaac atatgaaagt ggttgccact gcatatgcag gagatacaat aacatctact
    18301 ggtacaactc caagatgggg tgttattgca gttgacccac gtgtaatacc atatggaaca
    18361 aaagtatata tacctaaact gggtatgact tttgtagcag aagattgtgg aggtgcaatt
    18421 aaaggtaata gaatagacat ttttatgaac agtgaaggaa aagcttcaaa ttggggaagg
    18481 aaaagtatag atatatatct acattaaatt agtgaataga ataactttac ttgaaggaca
    18541 aaaaagtata aaatatgaat taactaaact gttagattat tcttaaaaca taaaaatata
    18601 tctaaggggg gataagatga aaatagtctg cttaggagac agtttaacgt atggatttgg
    18661 agtatcacga agtaattcat ggacaaacat tgtaaataaa gagactcgat tagaaatagt
    18721 aaataagggt ataaatggtg atacaacaag tggtatgtta gctaggttta atgaagatgt
    18781 tgtaaaaaat tctcctgata tagtttttat aatgggtggc accaatgatt ttattgctgg
    18841 tgcgggaaat gaaattatta attctaatat aatggctatg gtgcatcagt catattcaaa
    18901 aaatattata cctataatag gtataccatt aaaaccagat attccaaatg ttagggaaga
    18961 ttggagttgt tttactgatt ttaatatagt atctcaaaac ttagaatcat atagttattg
    19021 gataaaaaaa ttttgtatga catttaatac taatttcgta gatttttatt cagaatataa
    19081 taaaaatatg gaactagaag gatataaaaa attatatttt gatgggttac atccaaccaa
    19141 agagggtcat agaataatgg cagacatttt tattaattca attaataagt atatagaaga
    19201 gttatagatt acattaaaat gcttgtttat gcgtcagttg caataaatac atacagtaga
    19261 gaggggttta ttatggatta tactaaaact tatgaagagt ggataaaggg ttcatatttt
    19321 gatgaagata caaagctaga gttggagaat ataaaaaata atgaaaaaga aatagaggat
    19381 agattctata aggatttaga atttgggact gcgggtctta gaggaataat tgaagcagga
    19441 acgaatagaa taaataagta cacagttaga agagctactt ttggattggc aaactatata
    19501 ttagaaaaca caacaaaaga agaaacaagt agaggagtag taatagctca tgataataga
    19561 cacaagtcta gacaattctg tatagaatct gcaaatactt tggcagcatg tggtataaaa
    19621 gcatatatat ttgatagttt gagaactact ccagaattat cttttgctgt tagaagctta
    19681 aatgcaatcg ctggtatagt cataacagca agccataatc ctccagaata taatggatat
    19741 aaggtatact gggaagatgg agcacaagtt atgccagaga ttgcaaatgc aataacagag
    19801 aaagtaaata gtatacatga ttatagtaca ataccaacct taacggaagc taataaaaat
    19861 ttggtagttt tgttggacga atcacaagat actaaattta tagaagcagt aaaaagccaa
    19921 attataagaa aagatttagt taaaaatgta ggtaaaagct ttaagatagt ttatacacct
    19981 ctttgtggaa cagggaatgt tccaataaga agagcattga aagaagttgg ttttgaaaat
    20041 ataattgtag ttccagaaga agaaaatcca gacccaaatt ttgcagggct tgattatcca
    20101 aatccagaag agaaaaaagc tttaaataga ggtatattac tcgcaaaaga aaaaggagca
    20161 gaccttgtaa tagcaactga cccagattgt gatagagtag gtgtagcagt aaaaactact
    20221 acaggtgagt atgctttact tacaggaaat caaattggtg gtatgctgac acattatata
    20281 atagaaggat taaaagaaaa taataaatta aaagaaaatc ctacaataat aaaaaccata
    20341 gttacatcag aatttggagc agatatagct aaagcaaata atgttgatgt attaaatgtt
    20401 cttacaggtt ttaaatttat tggtgaaaaa ataaaattat ttgaacaaaa taaaaataga
    20461 agttatgtat ttggatatga agaaagttat ggttacttag ttgggactca tgctagagat
    20521 aaagatggtg tagtttcttc attgttaata tctgaaatgg cagcatttta ctattcaaaa
    20581 ggtatgagtt tatatgatgg tttaatagaa ctttataaaa agtatggatt tttcaaagaa
    20641 cagactatat ctttgacttt aaaaggtata gaaggtgtag aaaagataaa agaaataata
    20701 tcttatttta gagaaaatca aattgattat ataaatagta ttaaagtagt tgataaaaaa
    20761 gattataaaa atggtataga taatcttcct aaatctgatg ttttaaaata ctttttggaa
    20821 gatgaatctt gggtagctat aagaccatct ggaacagaac caaaacttaa attttacata
    20881 gctgtaaaag gagctagtga tattgaagca gataaaaaga ttcaaggttt gaaaaagtat
    20941 atagatgaca tggtcgaaaa attaaaataa aatattatta ttttataaga taattttgta
    21001 ataatattta tttagctgaa aattataatt tactttcatt gagtagaata tggaaatgtt
    21061 agtagaattg ttattttcag cttttatttg tgttattttt acttaaataa ttatattata
    21121 gaatgaatct gagtataatt aatattgtat aatgaaatta atttgataga aaaggggata
    21181 tttatgtttg gtatagataa gaaattgatt gaatatataa ttgcaaaatc caattacagt
    21241 gaattaagtt caaagtcagc agaagtatct ttcttcttaa tgttgtccat atttcctttt
    21301 ttaatattta caataagttc tatagcctat ataccgattc ttcatttaaa taagtatata
    21361 gccttgttta gaaatatgat gccagaaggt gcttttgctg tgttatcttc aatcatagtt
    21421 tctgcaatag acaatagaaa cctgaaattt ttagcagtca gttttgtact tactatgtgg
    21481 acattttcaa gagcagtaaa agctcttatt aaaggaatga atagagccta taaagttaaa
    21541 gaaactaggt ctttttttaa aattttatct atatcatttt tatttacaat aatgcttttg
    21601 gtccttattt ttttatctat gatattttta gtttacgggg aaaaaatagg ttattttatt
    21661 tttaatcttg taggattgga tgagatattt ataaaaatat gggatattct aagatacact
    21721 gtaggtataa taacaataat agtgatattt acacttttat ataaatacac tccaaataaa
    21781 aagttaacta ttaaagaatc tgcgccaggt gctatttttg ctacttttgc ttggttttta
    21841 gtatcatttt tatattctta ttatacaaat tactatgcta actatgaagt aatctatgga
    21901 agtatagctg aaataattgt acttatgacc tggatgtatt ttagtagttg gtctatcgtt
    21961 attggctatg aggtaaattc aagattgtat tttagaaaga taagacatga aatgttaaag
    22021 taaagtattt aaaataaaag agagtattta gtattataaa tgtaattgaa ttaataaaga
    22081 aatattgaca tttaagttaa aaagtctaga atttttctgg gcttttttta tttttagtat
    22141 aacttgacaa attttattta atgggatagt tttaatttat aatcatcttt aaaaagatga
    22201 ctattgataa gtaagagata aaattggtaa gtatcaaaaa atatactaaa taaaaattat
    22261 agtcctaatg agttaatttc tgtattttca aataatgcag tatttagtca tgtgttttta
    22321 tatgtgcctg tatttctaat taccaatata ttagaataag ctactgtaat taggtttaga
    22381 aaaaagcgac ataaataatt ataaacaaat aataaattac ataaaattaa atttattcac
    22441 aagtatatct tataaaatat gttataatta atagaaaatt gtcatataat taattaagta
    22501 gtattattat aaataacatt gaaaggtagt ggttagaata tggataccca taataaatat
    22561 gtaaatttta taaaaaatat acctgtacct tttttatatt gtagaattgt aaagagacaa
    22621 gaagatatag aatatcgagt agaatatata agtaagggta tgggcaaagt attacaatta
    22681 gaagaaggta tttgtgataa aaatatatta gatgtattgc ctgtatttaa gtctaaaaaa
    22741 tatttcaaag agttgttctc aaatgaagtg gattgtataa aaaggtacat tccgacactt
    22801 aaaaactgga taaatataaa aaaacagata ataggggatt catacataat tttgtatttt
    22861 ggtaaaattg tatttgatta tagacagata atcgattcct ttgataaaaa ggaaaaagta
    22921 gcttatatta aagacgaaga aggcatatat atagattgta gtgaaaattt aataccaata
    22981 ttaaataaca acattaaaac aacaaaagat atctttggta aaaatgatat agaagtatgg
    23041 ggagagaata caggaaaatt atttagagat gattatagag aaggagtatc tagtaaaaaa
    23101 agatttttac aaaatctttt tgaatatgaa gaaacatttt ttatggttga aaaatatttt
    23161 ttgtatgatg aagacgaact tttaggtact atagggatag tagacaatat aatatatagt
    23221 ggttacagta atagaaatta taactcaaaa gatttaatga agatgataga acactcaatt
    23281 ccagagaata tgttttataa agatgtgtat ggaaattata ttggatttaa ttcaggtttt
    23341 ttgaatttag cttgtatgaa taaagaagaa ttattaggga agaatagtta taaaatatca
    23401 gaagaagaag ctttaataga taagatattt gaaagtgata agggtgtagt tgaaaataaa
    23461 aaagtagtta catttgagtt aaatataagt atgaatgatg aaaacaagtg tattgagatt
    23521 acaaaaaggc cgttttttga tagctatgga agtgttattg gaataattgg aacagcaagg
    23581 gatataagta gaagaaaaag attagaagag gaaatggata aaactaggat ggaatttttt
    23641 gcaaatttat cccatgaact tagaacgcct ataaatttaa tatcatcttc attacaagtg
    23701 atagaaaaaa aagaagcaga tttaatagaa tcaaatgata ctttaaaaag aaatctaggt
    23761 ataataaaac aaaatggaaa tagaatattg aggttagtaa ataatgttat agactttaca
    23821 aaaatgcaat caggatattt agattttaaa ccagaagaat ctgatataat tgcatttata
    23881 gaggagatat gtatgtctgt agctgatttt gcaagccaaa ataatataca acttacattt
    23941 gatacagaaa tagaagaatt ttcaatgtta tttgattcag aaaaattgga aagaataata
    24001 ttaaatttac tttctaatgg aattaagtac aataagaaag atggaaaaat aaatatattt
    24061 ttatatgtga aagataatgt atttaatatg aaaatatctg atagtggaat aggaatacca
    24121 aaagaaaaaa tagataaaat atttaatagg tttgaacaga ttgacaatga actttcttac
    24181 agagttaaag gaagtggtat tggactttca ttagtgaaat ctttggttga gttgcatgag
    24241 ggaagtatat ctttaaaaag tcaacttggt attggaagtg aatttatagt ttcattgcct
    24301 gttagaagta aaaataatat tgaaaaatat aatcataaaa gagaaatcag caatgaacta
    24361 agtaaaaaat tagaaataga gttttcggat ttataagttt aaatataaaa aataaaattt
    24421 taaaaaagta ttgacaattg atttagaagg gtttaaaata aattacaaca taataaataa
    24481 aaaggcgatg aataggaaga gtaaatctaa ttcgattacc agagagaaga gtccattggc
    24541 tggaagactt tttaaattag agggattgaa aactacctag gagctacttt ctgaagtcat
    24601 ctgcattagt agattttagt aagaatagtc gttagctgcg ttaaagtgta aagtgagttt
    24661 tcatgacata tgaaaactaa attaggtgga accgcgggaa taatactctc gtccttatgt
    24721 tataaggatg agagtttttt gttatttaaa aatataaaca gtaatcataa taattataga
    24781 aaatataaaa gcgatgaata ggaagagtaa atttaattcg actatcagag aggaaagttc
    24841 acaggctgaa agactttcta agtttgagaa attgaaaact acctaggagc tgtggtctga
    24901 agttacttta aaaagtttta gtaagactaa ccgttaactg cgttaaagtg taaagtggat
    24961 tttatcaata aatgataaaa tcaaattggg tggaaccgcg agtatggact cgtcccttta
    25021 tatagggatg agtctatttt tattgcaata aaagattgaa aataaaaaaa aatcggaaaa
    25081 ttataaattt aggaggaaaa taaaatggag aataaagtga aaattggagt actaggatat
    25141 ggagttgtag gaagtggact tatagatata atagataata ataaagaaaa aagaaatata
    25201 gaaatagttg gaattttagt taataatttg gaaaaacata aggataaaaa atattctaat
    25261 ataataacta ataatataga tgatatattt aataaagata tagatatact tgttgaagtc
    25321 atgggtggtt tagaaccatc attatcttat ataaaaaaag cattaaacaa taaaattcat
    25381 gttgttacag caaataaaga tttgttagct gaatgtggag atgagcttgc aaaattagca
    25441 agtgaaaata aagtaagtat taaatttgaa gcttcagttg caggaggtat accagtatta
    25501 aaaccaataa tagaatcact agaaggaaat aatatagata gtataaatgc aattttaaat
    25561 ggaactacta attttatatt atctaaaatg tatgatgaga atctatctta tgatatggca
    25621 ttaagacaag cacaagaatt aggttttgct gaagcaaatc cagagtcaga tgtattaggg
    25681 tatgatgctg ctagaaaact atcaatatta tcaactctag cttatgacaa tagagtatat
    25741 tggaaagatg tgtatttaga aggaattaca gatatagatg aaaaagatat tgaatatgca
    25801 aaaaaattaa attgtaaaat aaaattgatt ggtcaaagta agtatgaaaa tgataaagta
    25861 agtgcttttg ttagacctgt tttagtagaa aaagataata tccttgctag aatagacaat
    25921 gagttcaatg ctgtcatagt gaatggagat tcagtaggag aagtttcttt tgtaggtaaa
    25981 ggagctggaa gtttagcaac aggaagtgcg gtttattcag atgttataga tataatagat
    26041 aatagagttt caagtataga ttcttttact aaagataaaa tacaagttaa taaaatagtt
    26101 agagaaaagt gtggagcact tcttagattt aaaaaatgta ataaagatga aattctaaat
    26161 atagttgaga attgtttagt aaaattcgat attttaaatg atgatgatga acttgctatt
    26221 atggtttatg ctgattctga atatgaaata aacaacagtt tatgtctaat aaaagataaa
    26281 ggatactgcg aaaaaatgaa taaaatgttg aaaataagtt aaaaaagaaa aaatataagt
    26341 ttatatgtaa catattttga cgattttaat actatatagt atgagatgaa acaaaacatc
    26401 tcataaaaaa attaaaatta aagggagaga tatgttatat ggaaaataaa aaatgttatt
    26461 cagaagattg gtatgaaaga ggagaatcta cagctaaatg gttccaaaat gatagagaag
    26521 aatatgaaag agaagcatat gatgaagata gagaaagaag aggttcaaac tgtggatgtt
    26581 cagattcagg agaaaataga cctagaaact gtgaaagatt tagaagagaa gctgagataa
    26641 gagaaagaga agcaagagaa gcattttgtg aatcttcaga gaaaaagaaa gaggcattag
    26701 catatgaatg tgaagctaga aaattatggg aagaagcaga aaaatactgg gatgaatatt
    26761 caaaatacaa ctataaagga atcgaatatt tagcagaagc tgctagatta tttgatgaag
    26821 gtatggaatg tgaagctaga agaaatggaa ataatggagg aaacaataat aattgttgcc
    26881 ataaatgcca taaatgtaat tgtaactgct gtagaaaata aaaaaattaa ttgacaaatc
    26941 aatagttaaa atatatcata ttatgtataa taaaaagaaa attcagaaaa aaataatgat
    27001 tagaagaaat ataagtatat ttattagaca aatagtgctc agttagtgag gtgagtacaa
    27061 tatgattaaa ctcccatcct ctagcttttg atagagggtg ggagttttta tttattgata
    27121 tatcttaaat gaggataata ttgtaaaata aatgagtatg agattgtaaa attaggaggt
    27181 aaaaaatgaa aagtattaaa acatcaagta tgaaagaaaa ggtagatgaa aagatattaa
    27241 gagagcaagt aagttctata atagaagata taagaaataa taaggatgtt gcacttaaaa
    27301 aatataatga gaagtttgat agaaatacaa gagatgaatt tagaattact aaggaagaaa
    27361 taaaggaagc ttataagcat gtagatgacg aatttataaa taacttaaag attgctgcca
    27421 aaaatataag agaatttgct aaagctcaaa aactaagttt tgaaaaccct tttgaaaaag
    27481 aaatttatcc aggtgtaatc ttaggtcaaa ctaatattcc aatagagtca tgtcttgcat
    27541 atgttccagg aggtcagtat ccattgtttt caacagctct tatgcttata atacctgcaa
    27601 aagtagcagg agtaaaaaga atagtggcat gttcaccaac tatgaaaaat actgaaaaga
    27661 taaatcctaa gacattggta gctatggata tagcaggtgc tgatgaaata tatgcaactg
    27721 gaggagttca agctatagca gcatttacat atggaacaga aaagattaat ccagttgaca
    27781 taattgtagg accaggaaat aagtttgtaa ctgaagctaa aagacaatgt tatggacaag
    27841 tagggattga ttttgtcgct gggccaagtg aagttcttat aatagcggat gaaacttcaa
    27901 atccagttta tattgcagct gatttattag cacaatgtga gcatgattta aatgcaagag
    27961 gaatattatt gacaaatagc ttggaagtag cacaaaaagt tgaaaaaaat atagaaagta
    28021 tgctaaaaga tttgccaaca aaggacatag catatagttc atgggaaaat aatggagaga
    28081 taatattggt tgatgatatg gaagaagcca ttaaaataag taatttttat gcaccagaac
    28141 atttagaagt tgcagtaaat gagtataatg atatttgtga tagattaact aactatggtt
    28201 ctttatttat tggaaatctt tctgctgagg tgtttggtga ctatgtttca ggtaccaatc
    28261 atacattacc aacacttaaa gcatcaagat atactggtgg tgtttgggtt ggaactttta
    28321 tcaaaacttg tacaaagcag atatttaatg aaaaagctat acaatcatta gcacctgtag
    28381 ctgaaaagct ggcaaaagaa gagggattat atgcacatgc aaaggctgct gaggttaggt
    28441 ttaaaaagta gtaaaaaatt ttattttggc agtcgagact tagtattaga ctgagataag
    28501 gaaaacgctg agaacctgaa taaatactat attttgtggg tctcggcgct tcttttatat
    28561 ctgtatataa tagaataata ctatctgtgt gtttaaatac taacttaata tttcttttct
    28621 aaataatgtt tatgaaatag ttaatatttt tagttaatac ttgaaaaaaa cttttgctaa
    28681 ctgtgcaaat tcatctgcat ttgtcaatat agcagggtgt cctccctgac taaaaatgta
    28741 aatacttgct tttgaaataa aagttgccat ttgcttgtac tcttcttcaa gattatgacg
    28801 acacatttcg tcttccttac ttcctgtaaa taaaattggc atttctaatt tacacaattc
    28861 tttatgaaac aaagggcgtt tctcgtttgc acattgcaat agagcttttg tatcaagatt
    28921 aacaacattc tcccaatctt ttccatgaca ccattcatag aattttcgtg cttgaatatc
    28981 ttgctttgat ttttcccttc cagtgattag attatctatg aagttatcat taagagtacg
    29041 tccatcaaag ctatctgcta taattgcttc aactaaatcg ggacgttcta atccagtatt
    29101 aacagctgcc catgctcctc cacttgttcc aattaagcca actttaccac aattcaaatg
    29161 ttcaatcagt gctattgtct gtaaggcttc atcatgccat atgtcaggag aaaattgaga
    29221 aactctatcc gactgtccat tacctaaaaa atcaattaag atacatctaa aattttctgc
    29281 atataatggc acaagtgctt taaacatatt agaagaacca gtattaccat gcaggaaaat
    29341 tatcggttta ccttgtccat attctttata aaaacaagaa ttaccttgat actgaaaata
    29401 tgacatatat tttcctcctt tttatttgtt aagttaatta taacaatata ggtatgaatg
    29461 aaaaacctca tgttctttct tagaataaaa atgtgccacg cataaaacgt gacacatttc
    29521 taattataaa ttttgctgtt taagtattct ttgtatgctt ttctctgtca aaaagtattt
    29581 ctctgataac tgcttgatac tcattccatt ttggaaattt atacagattt gagaattacg
    29641 agaagctaag acttgtttgg tgtttgtgtt ttcaccccaa tgctttttgt gctcttgctt
    29701 tttgggaata taaatcactt taccatctat atattcttgc acttgctcaa tcagttcttt
    29761 aggcagtaag tcaatcgaat tttgatagct cattttgcac ctcctaaata attattcttt
    29821 aggattagca aaggctactg ccactcacaa ttaaaaataa aattttttat tatgtacaat
    29881 agcctttgct atgcacaagt tccaattccc ataaactaaa tactcctttc tggtttgaaa
    29941 aattcatctg aacattgatt tcgcttttaa gatagagttc aatgacaaat ttacattttt
    30001 attatatata ttcagataga taattgcaac tgtctttgta tgaggatatt ttattatagt
    30061 caatactata atatgtattt atatcatcaa actaatatga acagttgaaa ggaatatgaa
    30121 caataaaact tagtcaggaa gaataattat gaagcagaca atagagaaat ttgattttaa
    30181 agttttattg aaaatttatt gacaaattta acttgtaaat attatactaa acttaataaa
    30241 taaagtttat aaagtaaggt gttgtctatg aaaaatatag ttggaaaacc gcaaacgata
    30301 aaaaaagtaa atgaagattt aataaaaaac attataaaaa atgaaggtcc tataacaaaa
    30361 ccagaaattt caagcattac tgaattgagt ttagctacag ttaataagat tgtagagcaa
    30421 ttagctttga aaaatgaagt taaagtaagt ggactaagtg aatctactgg aggaagaaga
    30481 gctcaattat ttgaaataaa tgcaaactta gaacacataa tagctttata ttattataga
    30541 aattgttgta taggggtagt tgccaattta ttaggtgaaa taatttatca agaagaattt
    30601 aatataagaa tggatacgta tgaaaacgtt aaccaagata ctttttttgt tatagatact
    30661 ctaataaaaa aggaaaaagg aaacaatata agggctattg gaattggtgt cccaggagtt
    30721 gtaaaaaaag gtgtagttaa aaatatacca actataaaaa gttgggaagg tataaattta
    30781 gaaaatttaa taaagagtaa atacaatact aaagtgttta tagaaaatga tacaaatatt
    30841 actactattg ggatttatca aaaacagtat aaagacaaat ataaaaatat ggctcttatg
    30901 tatttagaag atggtattgg ttcaggtata gttataaatg gtgaattgta tttaggttct
    30961 acaaattttg ctggagaatt aagttatcta aatatagaat ttggtaagta taactctaac
    31021 aacttaaatc ttgaagatta tattatgagt ttaagaaaaa gatatttaga aagtaaagat
    31081 aataaattta agaaagaaat tttatctata atatcaaact ttataaggac tcttgtatgt
    31141 gtcctaaatc cacaagctat gattatacag tgtagtatat taaccaagag tgacatggag
    31201 tttatagaaa aagatgtaag caataatgtt ggagaagaaa attttcctaa attaataaaa
    31261 gtagactcat tgagagaagg aagtataaat ggagtaatta gtatgtgttt aaaagaaact
    31321 gactatcaat attccttatc taataaaaaa ggaggatatt aatgtgaaat atttggtttc
    31381 aatagatgga gggggaacaa aaactaaatt ttgtgtaagt gacttagatg gaaacatact
    31441 taaagaacat accactggtt caactaatta taagtcagtt ggaattaaaa aaacatatga
    31501 aaatattaat aatggattta aaaaaatatt aaaagattta tatatcgatt atgacgatat
    31561 tgagtacact gtatttggta tatctggttg tgattctcct aatgattata agattataat
    31621 ggatgaaata ttaaaaattg ggattaacaa agaaaaaata tatctggcaa atgatgcagt
    31681 tttagctttt tatgcacaag ctgattcccc tggcttagta attgtggctg ggacaggttc
    31741 aattatactg ggaattaaag aagatggaga aatatataga gttggtggat gggggtataa
    31801 ttttagtgat ttgggttctg gatatgatat agggagaaaa ttattaaaga aagtattgct
    31861 ttattgtgat gaatgtcatg agtatagtga tttatttagt tgtgtcttgg acttctttgg
    31921 agcaaatagt tttgaacaac ttgcatatat gattactgat ataaatgata atgttgaaat
    31981 agcaaactta gcttcattag tgattgattg tgccgaacaa ggtgataaat tggctattga
    32041 aatattaaga gaatcatcaa ctgaactatc taaattagct caagtaatat tgagaaaaat
    32101 atctaatcca atgaaaatgg ataaaagcga aataaatata gttttgtctg gtggtacatt
    32161 aaataaaact gtatatgctc aaatgttaat gaataattta aaaacagaaa atacagataa
    32221 aaatttaaaa tttatatctc aagaaaatca gccagtatat ggggggataa gacttgctat
    32281 ggcattagct aataggaggg tcaagcatgg atagaaaaaa ggtaatagta caaattttta
    32341 ctggaggttt taaggctaaa gaaataaagt ttaatgatat aaaatgtaaa ctactagaat
    32401 tattggactg tattgatata gaaaaggtta tcatgggatg gagtgtagat gaagaattat
    32461 atgtagaaac taaaaaacta ttaaataaat ataatgttga actatatctt tggttgccat
    32521 gtttttctga aataggatta cttgaaaaaa gtaatttact aattgattat atggggaagg
    32581 aagtcaaggg ctatgcttta caagaggatg aaaattttga gttttattgc ccaaataata
    32641 aggaaaatat aaaaaatata aagaaaatat atagtactta ttttagtgat attaaatttg
    32701 atggaatttt tttagataaa ataaggtatg gttctttttc gaataaacta aatggtgttt
    32761 ttaattgttt ttgtaaagat tgtttaaata tatataaaaa aaataatatt gataaagagt
    32821 cgttaatgag agaaatgaat aatgtgtcta agggagttat agataatgaa gatactccat
    32881 ttggtataac agaatacatt aatggaaaat acaaatttaa aaataaaata tgggaagatt
    32941 tttttgaaac aaaaaatcaa aatatataca aggcattatt agagataagt agttatttta
    33001 aaagtaaggg attgaaaata ggtatagatg ctttttctcc ttttatttct tactttacag
    33061 gtcaagattt agaaaaatta caagaagtag cagattttat aaaaccaatg atgtatagaa
    33121 ctacaaaagc tccagctggt ttaccatttg aatttgaaag gtttattgat gaatccatac
    33181 ataagaataa agagattgga aaaagaaatt tcttagatat tttaggaatt aaggagtatg
    33241 aaggagatgt atatcctata gaatttgtac tagaggaaat cgattttatg acaagaaatc
    33301 ttaataaaga tatatatgta ggagttgaaa taaataaaaa ggaaattata tctcctgtta
    33361 cacctaagta cataagtgaa aatatttcaa atataaataa gacaacagta aaaggatatg
    33421 ttttatcttg ggatttgttg tcagcaccaa aagaaaatat tgatgaaatt ataaaatggt
    33481 ttcggaatta gtgaggtgat aaagtgagta agatattgga aatacaacaa atatataaaa
    33541 gttttggaaa ggtagatgtt ttaaaaggga taaattttga gttagaaaag ggagaagtaa
    33601 gagctctttt gggagctaat ggagcaggaa aatctacact tattaaaatt ttaggaggag
    33661 ttcattctca aactaaaggt aaagtaattt tgactggtaa tgaaataatg tttaaaaatc
    33721 cacatcattc taaagaaaat ggtattagta taatttatca agaattaagc ttgataccaa
    33781 cgcttacagt acttgaaaat atttttcttg gtagagaaat tttaaaagga agtgtgtttt
    33841 taaacaagaa agacatgctt gaggaatata tgaaaatttg tgaggatttt gattttaata
    33901 tagacccaca tatagtagtt tctaatttaa gtgtagcaaa ccaacaaatg gttgagataa
    33961 tgaaagctgt ttcatgtaat tctgaaatta tcataatgga tgaacctaca acatcactta
    34021 ctaataatga aaaagatggg ctatttaaaa taataagtag actaaagtct aaaggtaaaa
    34081 caatagtcta tatttctcac atattagagg aagtttttaa agtatgtgat agtgcaagta
    34141 taatgaaaaa tggaattatg attggaactt atgatgtaga ggatttaact aaattaaaga
    34201 taactcaact tatgacagga aatgataatc acaaacttat tgagaagaag gattatacat
    34261 ttgcaaaata tgaagagcca ccagtactag aagtaaagaa tataagctgg tctaacaaaa
    34321 taaaaaatgt ttcatttaaa gtttatagag gcgaagttgt aggtcttgca ggtcttgtag
    34381 gttcaagaag aactgaaatt ataaatttga tatttggtat agataataaa gatagtggag
    34441 atatttttat caatggtaaa aaagtagaca taacttctcc taaggttgct ataaaaaaca
    34501 aaataggatt gattcctgaa gatagaaaaa atctaggatt aattttagaa caagctatat
    34561 acacaaactc atcatcagta caaattgata aattcaagaa atttttgttt atagatagaa
    34621 ataaagaaat tgagttttct aaaaaaggtg ttaaggaatt aggaataaaa gttagtgatg
    34681 taaagcaaga agtaaaagag cttagtggtg gaaatcaaca aaaagtagta gtttctaagt
    34741 ggttagagaa agatttagat ttaataatat atgatgagcc gacaaaggga atagatattg
    34801 ctgcaaaaga agatattttc aatacaatca aagaattttc aagtaaagga ataggagtaa
    34861 tatttatatc ttctgattta gaagaagtaa taagagtaag tgatagaatt ttagtaacta
    34921 gagaaggttc tattgtagat gatttaaaaa atgagaatat acaggttcaa gatataatga
    34981 acagtatatt taatgtataa aaaatgaaaa tggaggactg agatgaagaa agcttttgag
    35041 aagttaaatt taagagatta tggagtatta ttaggttttt tagctttatg tatagctata
    35101 agtattgcaa ctccatcatt tttaggtaaa caaaatatac ttaatctttt acgacaatct
    35161 tctataattg gaataatttc agcaggtatg acttttgtta taatatctgg aaactttgat
    35221 atatcagttg gagcagtagc agctcttgca ggtgctataa caatgaaatt tgcgactggt
    35281 ggaactaatt tgtttgcatc catgttctta ggtgtagcga tttgtgcagt aataggatta
    35341 atcaatggta tagtagttgc aaagataaat gtaccatcat taatagccac tatggctatg
    35401 gtcactattg taagaggatt gctgttgatg cttacaggag gatatccaat tactgaaaat
    35461 ataccaatac ttgattacat tggaaatgga tatttgttta atataccaat accagtagta
    35521 attttcttta tagtggtgtt agcttcgttt attgtactta ataaaactaa gtttggtaga
    35581 tatgtttatt ctgtaggagg gaatcaagaa gcaagtaaac ttaatggtat aaatgtagat
    35641 tctcacaaag tgaaagtgtt tattattaat gctgtacttg caggaatagc tggaatcgta
    35701 ctaacaggaa gacttgggac tgcaactgcg attgcaggtg aaggatatga tatggatgca
    35761 attgcatctg tagtaatagg aggtacatca gtggcaggag gttctggttc tgtacttaaa
    35821 actgttatag gagtattact tatgagtgtt ataaacaaca gttttaatct tcttggaata
    35881 gatgtatatt tccagtacat atttaaagga ttaataattt tagcagcagt tggatttgat
    35941 tcttatagca agaaaaaact tgcttcaaga taaaaaataa gggggatttt tttatgaaaa
    36001 aattaatgaa acatttagca ttgttgctat cacttgttat gatatttggt ttagttggtt
    36061 gttcaaatgg tggtgacaaa gaaaaaaatg gagaaaagaa aatagcagta ttactaccgg
    36121 gttcaacagg ttactttgta gcaactaaac aaggtataga tgcaaaatct aaagaattag
    36181 gtgtaagcgt ggaatatgca gatgctcaat gggatgctag taaacaatta tcacaagctg
    36241 aagattttat ggctaaaggg gtagacatga ttgcattatg tggagttgat tctgctgtaa
    36301 gtgagagaat agttaaagct gctaatgatt cagacgttcc tatagtagca tttacaaatt
    36361 ctataggaag taacccaact ggagaattta aaggtttagt tacatatata ggacaaaatg
    36421 aggaagaaac aggagcatta actggaaaaa ttgctaaaaa cttattagga gaaactggtg
    36481 ggaaagctgt attaatagaa ggagtaccag gaactactcc acaagtatta agaaaaaaag
    36541 gtcttgaaaa agaattaaaa gatagtaata tagaaatagt ttataatcaa acttcaaatt
    36601 gggagaaaga gcaagcttta aaggtaacag aagatttaat tcaaaagaaa actgatttta
    36661 atgttataat atgtcaagat gataattctg ctacaggtgc aggtcaagct ttaaaagatg
    36721 ctggtcttaa ggataaagtt aaagtcatag gtttgggtgg aagtaaagat ggattaaaag
    36781 ctataactga tgggttaata gatggtacaa cttatatgtc tgctgtagaa gaaggtggat
    36841 tagtcataga aaaggcatct aaattcctta aaggtgaaaa aatagaacct gttacacaaa
    36901 ttaaacaagt tgaagttaac aaagataata tttcagagtt caagggtgaa tggtaaattg
    36961 tcatagataa taaataagat ttttagagtt actttagaaa ctatataaag taactctttt
    37021 tttaatttaa tttagtgata aattattgaa tagtatttct aaacaaataa aaaattaata
    37081 taaacaaaga cttaattata ctaaattata agtaaaacta atataaactt atggaaaaaa
    37141 ggaaaacgtc taaagtattg gaattactat agtgtaggtg tggtattaaa aaaacataaa
    37201 aaaacataaa aaaattgttg aaaaaaatat agaaattttg tataattaaa gatttgaaaa
    37261 gtgcggtata caaagccaat tcttttgtat ataatatata taaattcaga aaaaggaagg
    37321 gatatgtatg gccaggcggt tatttttaga aaggattgga cttatatttt taggttcagc
    37381 aatattagca tttggagttt ataattttta ttatttaaac aacataacag aaggtggagt
    37441 gttaggtatt ttactactgt taaaaaattt attcaatata caaccagcaa tagcaaatgt
    37501 tgtaatagat agtttactac ttttagtagg atataaattt ttcggtaaaa aattccttat
    37561 atattcaata gtagcttcta taactttttc agtgttatat gacttatttg aagctatagg
    37621 acctctagta ccacaatcac aaaatatgct tttatcaact attttggcag gtgtaactgt
    37681 tggaactggt gtaggtatag tagtaaaagc aggttgtgca tcaggaggag acgatgcttt
    37741 agcattagta atttctaaga ctacatcttt gaacataggg caagtttatt tagcaacaga
    37801 tgttattgta ttgttgttat cattatttta tctatcagcg tttgatatct tttattcttt
    37861 gattgctgtt acaattagtg gcaaggtaat tgattttatt tattatcatg gtaaaagttt
    37921 ggatatggat ataagtaatg atatagttcc agaatgttaa tataaattaa ataactttag
    37981 attttattag gggtggcaga tttgccacct tttttttgtc taaatcttta tagaaagtat
    38041 aatcccatct aggtttttgc aaatctcaaa tatagaatta tgttggaatg actgggaata
    38101 cgattgctag atgtgcattt taaaaaccca attttatatt tatgaaatac taatcattaa
    38161 tggatgtttc ttaatcctat ctttatacct aaaatgataa gataaatgaa gtagcaatac
    38221 aaagctaaaa tttgtaaaag agattaaatt aaatggagga gctaaaatgt tggatatagt
    38281 tatgatagca ttgttattca taggatttgt ttccatgaag ttacttgctg attggtgtgg
    38341 gaaacaaact gaaaaaaaat aatgtaatgt atggagggat tacctatgtg gtttctggca
    38401 gttgtaatta taatgttaat aatatatttg gtatatgcgc ttattaatcc tgaaaaattt
    38461 taaacagtat aaggctaata agtaagttga attgggggga acaattttta tggtgcagat
    38521 agtaatagtg ttagcgattt ttatgatttt agtaatacct atgggcaagt atttatatca
    38581 tatagctact aatcaaaaaa catttggaga tagactattt gataaagtgg acaattttat
    38641 atataaggta tgtagtatag ataagaaaaa agaaatgaac tggaaacagt atgcattagc
    38701 tttattattt acaaatgcag ttatggtatt tataggatat atcatactta ggactcaaag
    38761 tatgcatatt tttaatccaa gtggaattaa aagtatggaa caaggactat catttaatac
    38821 aataataagt tttatgacaa atacaaatct tcaacattat tcaggtgaat caggactttc
    38881 atactttagt cagatgacag tgataatata tatgatgttt acatcagctg caacaggata
    38941 tgcggctgct atggcatttg taagaggtct agtcggtaaa aagaaaacat tgggaaattt
    39001 ttatgtagat ttaattagga taacaacaag agtactttta ccaggagctt taattattgg
    39061 gcttatatta gttacacaag gagtaccaca aacttttgct gggacagaaa cagtgactac
    39121 tatagaagga aagcttcaag atatagctag aggtcctgtg gcagctcttg aatcaataaa
    39181 acatttagga acaaatggtg gtggattctt tggttcaaat tcatcacacc catttgaaaa
    39241 tccaacaata atatcaaata tagtagaaat attatctatg atgatattac caggagcttg
    39301 tgttgttgca ttcggtcaca tgataaagaa taaaaaacaa ggttgggttg tgtttggcgc
    39361 aatgtcaatc atatttttaa taggtctagt agtgtgcttt aaagcagaaa gtgcaggaaa
    39421 tcctatttta tcacaattag ggcttaatca aagtatggga agtatggaag gtaaggaagt
    39481 tagatttggt atagcacaat catcattatt cacaacagtg actacttcct ttacgacagg
    39541 tacagttaat aatatgcatg atacactgac tcctttagga ggattagtac cacttttaaa
    39601 tatgatgcta aatgtagtat ttggtggtaa aggcgtaggt ctgatgaata tgttgatgta
    39661 cgctataata gcagtattct tatgtggatt aatggtagga agaacaccag agtttttaac
    39721 taagaaaatc gaaggaaaag aaatgaagct tattgcttta cttattatat tacatccact
    39781 tttaatacta atgttctctg gtctttcagt agcaatacca gcaggacttg aaggaatttc
    39841 aaatcctgga ttccatggat tatcacaggt attgtatgag tttgcatctt cagcagccaa
    39901 taatggttca ggatttgaag gtctaggaga taacactatg ttttggaata taacaacagg
    39961 tatagttatg ttctttggaa gatatgtgtc tattatagta ctactagcaa tatcaagttt
    40021 gttagcatct aaaaaagctg taaatgaaag tataggaaca cttagaacgg ataattttac
    40081 atttacaata gttttagtac ttgttgtttt aattgttggt gctttaacat ttttcccagc
    40141 cttagcgctt ggacctattt cggagcatct agtgttgtgg cactaaaaaa ttgggaggga
    40201 gtaaagtttt atggaaacta aaaaaacaaa gtttattaca aaagatattt tcaaaacttc
    40261 cattatagaa gcttttaaaa aattaaatcc taaatatatg atgaaaaatc cagttatgtt
    40321 tgttgtagaa attggattta tagtaacatt gatacttaca atagtaccta gtttgtttgg
    40381 tgatgaaggc aataacttaa gagcttataa tgggattgta acaataatct tatttataac
    40441 agtccttttt gcaaattttg ctgaagctgt agctgaagga agaggtaaag ctcaagcaga
    40501 tacacttaag aaaactagaa aagatacagt agcaagggtt atagatacgt taggaaatga
    40561 aaaaatgata agtgcaagtg agctaaaact tggtgatatt gttttagtaa atgctggaga
    40621 agttatccca aatgatggag aagttataga gggtatagct tctgtggatg agtcagcaat
    40681 aactggagaa tctgcacctg tcatgagaga atcaggtgga gatttcgcat ctgttacagg
    40741 tggtactaca gttgtaagtg actggttaaa gataagaata acaacaaaac caggagaatc
    40801 gttcttagat aaaatgatag ctcttgtaga aggtgcttca agacaaaaaa cgccaaatga
    40861 gattgcttta aatactttgt tagtagggtt aacacttata tttatggttg ttttaatatc
    40921 tctttatcca atggcaaact atgcaggtgt aaagattcca atttctacta tgatagctct
    40981 tttggtatgt ttaataccaa ctactatagg tggattgttg tcagctattg gtattgcagg
    41041 tatggataga gtaactagat ttaatgtaat tgcaatgtca ggaaaagcag tagaagcttg
    41101 tggagacgtt gatactatga ttttggataa gacaggtaca attacttatg ggaatagact
    41161 tgcatcagaa tttatagcag ttggaaatgc agattcaaaa gatttaataa attattctgt
    41221 tatgtgttca ttaaaagatg atacaccaga aggaaaatct atagttgatt taggtatgaa
    41281 attaggttca acaggtaaga caaaagaggc agaggaagct gagtttgtag aattttctgc
    41341 acaaactaga atgagtggta ttaacttagc tgatggtaga gctataagaa aaggtgctta
    41401 tgatagcata ataaaaagag taaaagaatc tggtggtaca gtgccagaag atttagaaga
    41461 aaatgtaaat cgagtagcta aactaggagg gacaccttta gtagtgtgtg tagataatga
    41521 gatatatgga attatctact taaaagatac agtaaaatca gggcttgtag aaagatttgc
    41581 tagacttcga gagataggaa taaagacaat aatgtgtaca ggggataatc ccttgacagc
    41641 agctacaatt gcaagagaag ctggagtaga tggatttatt gcagaatgta aaccagaaga
    41701 taaaatagat gcaataaaaa aagaacaatt agagggtaaa atagttgcaa tgacaggtga
    41761 tggaacaaat gatgctcctg cacttgctca ggcagatgta ggtcttgcaa tgaatagtgg
    41821 tacaacatct gcaaaagaag cagcaaatat ggtagattta gattcagacc caactaagat
    41881 attggaagtt gttgaaatag gaaaacagct tttaataact cgtggggctt tgacaacatt
    41941 tagtatagca aatgatgttg caaaatattt tgcgattata ccagctatat ttactcttgc
    42001 aatacctcaa atggagatat taaatgtaat gaaactttct acatcattta gtgcgatatt
    42061 atcagcttta atatttaatg ctataattat cccatgttta atacctcttg caatgaaggg
    42121 agtaaaatat agacctatga aatcacaagc tatgttaatg agaaatatgc ttatatttgg
    42181 tcttggtgga gttatagtac catttttagg aataaaatta attgatttat tgattacacc
    42241 tttagtaatg gttcttaatt taggttaata aatggaggat ataaaaatga aaacattaaa
    42301 gccagcatta cttgtaagta ttgtattgtt agttgtttgt ggacttgtat atccacttgt
    42361 tttgacaggt gtaagccaag ttgcatttaa agataaagcc aatggaagta tgatagaagt
    42421 aaatggtgta aaagtaggtt cagaacttat tggtcaaagc tttacagatg tgagattctt
    42481 taagggaaga gtatcatcag taaactataa tacttataca aaagaagatt tagtaccaga
    42541 taaagatgga aacacatctt atggaggtgt atcatcaggg tcttttaatt atggagctac
    42601 aaatccagaa cttcatgata gagtacaaaa agatatagaa cagtttttaa aggataatcc
    42661 aactgtcaaa agagaggata taccaacaga tttacttaca gcatcaggtt caggacttga
    42721 ccctaatata agtccagcct ctgcaaaaat tcagatacca gctatagcaa aagcgtctgg
    42781 aatatcagaa agtaaattac aaaaaattgt agatgataat acttccaaaa aactttttgg
    42841 agttttaggt gaagatagag ttaatgtatt aaaggttaat gtagaggtcg caaaaatatt
    42901 aggtcttata tagtattttg tggaatttta gcaacaaaat attacgcaag atttaattta
    42961 aaggttaaat tttaaagagt gaaaatcgat aatgattttc acttttttat ttgaatatta
    43021 ctaatatttg gaataaagtg attgtaagta taaaatccaa aaaaaggttg cattatcaaa
    43081 atgataatac tataatatat ttatcgttat caatttgata atagatttgg acatatagga
    43141 ggaaatagta tgttatataa taacgcatta gagttgatag gaaacacacc tgtagtaagg
    43201 ctgaataatt taggctgtac taatgggtgt tctaacatat atgtaaaatt agaaaaagta
    43261 aatccagcag gaagtataaa agatagagct gtttatgaaa tgttagaggg cttagagcaa
    43321 agaggagaat taaaaaaggg agatgtacta gttgaagcaa ctagtggaaa tactggtatt
    43381 gcattatcta tgataggaaa attaaaagga tatgaagtag taatcgtaat gcccgaaaca
    43441 atgagcgttg agagaagaga tttaatgaag gcttatggag caaatttggt gcttacagat
    43501 ggtaaagctg gaatggcagg ttccatagaa aaagcaaatg aacttttaaa agaaaatcca
    43561 aactataaaa gcctaaaaca atttgaaaat aaagataatc caaatgcaca ttataaaaca
    43621 acagcagttg aaattatgaa tgatgtcaaa gatttagata tattcgtatg tggagttgga
    43681 acaggtggta ctttaatagg aactgcaaga tatttaaaag aacaaaatcc aaatataaga
    43741 gtaattgcac ttgaaccaaa aaaatctcca gctatatcag aaaacaagac tggacctcat
    43801 aaaatacaag gaataggtgc taactttgtt cctgaaaatt atgattctag tgtagttgat
    43861 gaagtaatat tagtagatga tgaagatgca tttgatacag ttaaattact tgcagcaaaa
    43921 gagggaattt tagtagggat atcttctgga gcaaatatat ttggtgctat agagatggca
    43981 aaaaagtatc cagataaaaa gatagttaca gtagctccag atggagttga taagtatatg
    44041 tctatgggaa tattttaata attttatttg agggagtgaa tactttgttt aagaaaataa
    44101 ataaagatat tgaatatata atgaagaatg atccagcagc taggtctaag atagaagttt
    44161 ttttacttta tccatcagtt catgcaatga taatgcatag gatggctcat gctctttata
    44221 agaagaagaa gctttttaca gcaagattaa tatcccagat atccagattt atgactggca
    44281 tagaaataca tcctggtgct aaaatggggg aaggtatatt gatagaccat ggaatgggtg
    44341 ttgtaattgg agagacagcg gaagtaggga atagggtgac aatatatcaa ggagctactt
    44401 taggagctac aggaaaagat actggaaaga gacatccaac tgttggtgat gatgtattaa
    44461 ttggtgctgg aacaaaaata ctaggacctt taaatatagg ttcaaattca aaaattggtg
    44521 caaattctgt tgtcgttaag gatgtaccta atggtgcaac agttgttggt ataccagcaa
    44581 aaatagtaaa aataagaaac ctagaacctg taaaaaagaa taaaaaagaa gtgtcctatg
    44641 agtatgatga attagataat gtatattata tataggattt atataactat aaaataaact
    44701 ttataaaaat tattttaaaa ggtatttttt tcaaatttga ggacataata aaaaagaact
    44761 gaatgttaca gttttggttc atcaatcttt gataaacaag attttaaatt tgtagcgtct
    44821 aggaggattt tattatgaaa gcaaatgtta atcaagatac ttgtataggt tgtggattat
    44881 gtccatcaat atgtccagaa gtatttgata tgaaggatga tgggaaatca catgttatag
    44941 ttgatgaagt accaagtgat gctgaagaat cagcagcaga agctagagaa agctgtccag
    45001 ttgatgcaat agatgtgcat taataaaata aatgcctata aaaattgaat tttcaatttt
    45061 tataggcatt tgtcttttat tcagttagta tttcaacacc tgtttctgta actaaaacca
    45121 tacattccca ttgagcagat aatttaccat cttttgtata aatagtccaa ttattttctt
    45181 catcaacaaa aatttcgtga gttccttcat ttaccatagg ttctattgtg aatatcatcc
    45241 caggaaccaa tagcatctta gtcccttttt tagatacata acttacaaaa gggtcttcat
    45301 gaaagcttaa tccaactcca tgaccaccta tttctctaac aacagagtat ccatttttct
    45361 ttgcataaga gttgatagca tcacctatat ctcctaaaaa tccccatggt ttggcaactt
    45421 caagaccttt ttggacacat tcctttgtaa cttgaactaa tttttttgca ttttcattaa
    45481 cattacctat cataaacatt cttgaagcat ctgaatagta tccattaaaa atagtagaaa
    45541 catctacatt tataatatct ccatctttta agataatgtc cttacttgga ataccatgac
    45601 aaacttcatt atttactgat gtacatacac ttttaggaaa tccattatag tctagtggag
    45661 cagggatagc tccattttgt agtgtaaagt catgaaccaa cttatttata tcttctgtag
    45721 acattccaat ttcgatttta tctgaaatat aatccaaaat ttttgtgttt attacagcac
    45781 ttttttttat ttcctcaatt tgactttcat tttttataat atcatgagtt ggtacaatat
    45841 gacctaactt agcaaatgaa tctattttat tatccatatc catatgacat tttttatatt
    45901 ttttagtact tccacaccaa cagctatcat ttctatttaa cttcataact tttcatcctt
    45961 cttttattat ttatttaaat tatgggttac ataaactatt ttaaaacata accattataa
    46021 atattataac ataaatacta agaaatcctt tatagatagt gatttattca aagtataaat
    46081 tattatatgg ttattgttga tgaaaagagg atagttaaat gtattattgg atattagcgc
    46141 acttaatagt ttaattcaag tttttcaaga aaatcatatg ttagaggaca attttccttt
    46201 aaagtatttt ttgaatcttc atcaagataa taatgcacaa atgattctgc aaaaaattct
    46261 tctataaact tgcttatata tgcatgtgca acttgcttag ggtcataaag cttatatctt
    46321 tcctgagcaa atacttccat aaattcttca gaatttgatt ttttatttaa aacattttta
    46381 tctatagcat gtgcagtttc atgtaattct aaattttttg atgaatgtac atttgcatag
    46441 ctagggttac tataacctat tttagccact atagaattat ttctatatat accaggtaca
    46501 tctttccaag tcttgcctga tcttacccaa catggaggta attgatattt taaatcacta
    46561 aattctggtt catcagttag atttgaattt attaatttta tttttatatc cttttcttta
    46621 agtgtctgta aatatttaat atttattttt gcaagtctgt ttttcatatt ttcaacttca
    46681 tctttatcat aattcaagtc atcaggaagt ataagcattt gttcaattat atctatacta
    46741 ctgtctttta tattttcaga ttcttcatta aatttatatt gaagagtatt attttcatag
    46801 atagttatat ttgtattatt ttctatagaa taagagtgaa tatcctctaa atctaaaata
    46861 ttcatttgtt gtaaaatatg ttttgtttcg ccactccata ctactaaaga aagtgaatta
    46921 aaattaatta gtggattttc ttttgctttt atatcattgc ttatatctac atcaaataca
    46981 tattcaattg agtcttctat gttaagacta tctgtattct ttttaatata taaatacgct
    47041 tgttttaagt ctatataaat ctcatctaaa gattcgtcat aaaattctga taaattatta
    47101 gtaaagagtt cttcacttaa aagttcattt ttatcagtta tactttcaat taaaatatta
    47161 atttctttta tcatatcgta aatacttatt tttctatttg ctttttcact agatacattg
    47221 catggcgcaa gagcaatgca ataaaaatct ttttcttttt tataaaaggc tttaagtgat
    47281 tttgataaaa gtgtaaagtc tacacctatc tgtaagttga ccttaagtga gtcattttgt
    47341 aataattcag tattatttct tttagctgta tttaaattgt tttccataat cattgccccc
    47401 tttttattag ggtatcataa tttttttata tgtgtcaatt tgtttttttg aaaattataa
    47461 tttttttgaa aattttattt tttataattt gtgaattttt tattatagaa ataaatatgt
    47521 tattattatg tcaaaattta gcattagatt catgtagagt atgttttata catatattat
    47581 aattaattct ttgaagattg catattcaaa atacacacca ttttttttaa ttctataata
    47641 taatatttat atatttaatg ttaggatgtg atttaaggtg tattttacat atattataag
    47701 atgtaaagat gattctctat acactggata taccagtaat atagttagaa gaatgaatga
    47761 acataaatta ggaattaatt caaaatacac aagagcaaag ggatttgaaa aactagaagt
    47821 ttattttgtg accaacacaa aaagcaatgc tatgaagtta gaatactata taaaaaaatt
    47881 aactagaaat aaaaaattgt ctataataaa aaacccaagt atacttataa atttaattga
    47941 taataaagaa gattatatta ttggtaagga aatagaacaa ttaacataaa tatttatagt
    48001 aacattataa tgggtgcata tggtgtaaaa acttgacaat aaatactatt gtaatataat
    48061 gaagttataa atatagtaaa ttaaaatagc taggggagcc aagagctgag aggtataccg
    48121 acccttacac ctgatctgga taataccagc gtaggaaagc ttagtaaaaa ttcaagtatg
    48181 tattatttgt gatatatgct atttctaagc tatacctatt gtaggtatag cttttttaat
    48241 taagttattt aaattaaact ttaggaggca acaatgagta attataaaat accaacactt
    48301 acaatagccg gctctgattc atctggagga gctgggattc aggctgattt gaaaacgttt
    48361 agtgcaattg gtacttatgg tatgagtgta ataacagcta taacagcaca gaatactaaa
    48421 ggagtttttg ctgtagagga tttaaataag aaaataataa aaaaacaaat agaggcagtc
    48481 tttgaagata tacctccaag agctgtaaaa ataggaatgg tttcaagtcc tgagattata
    48541 cttgaaatag ttgagaatct aaagaaatac aatccaaaat atttggttgt ggacccagta
    48601 atgatatcta aaagtggata ttatctatta aagccagagg caaaagaaaa cttaattaag
    48661 tatttgatac cacttgcata cataattaca ccaaatatac cagaggcaga agaaataaca
    48721 ggaataaaaa tacataatgt agatgatatg aagagagtag gagaagaaat actacaactt
    48781 ggacctaaat ttgtacttat gaaaggaggt catttagatg gagaagcagt ggatatttta
    48841 gttggtaaaa atatatttaa agtttataaa agtgaaagaa ttgataaaaa aaatacacat
    48901 ggaacagggt gcacattatc ttctgcaata acatcttatc tagcattagg atatgaaata
    48961 acagaagcag taaatctaag taaaatctat ataacagaag caataaaaag aagttttgat
    49021 ataggtcatg gagtaggacc agtacatcat ttttataaat ttgagtaata aaaaaatatt
    49081 ggaggtagaa tatgtataat ttaattaaag atgtaaaaaa attaaatcca ttggtaattc
    49141 attatactaa taatgtaact ataaatgatt gtgctaatgt aactttagct gtaggagcaa
    49201 gtcctcttat gagtttttca tatgaggaag tagaagaaat ggtaagtgta gcaaactctg
    49261 tagtaataaa tataggaact atgaactcaa atatgttgga tttattccta ttagctggaa
    49321 aagcagcaaa taagtacaat aaacctgttg ttttggaccc agttggagta tttgcaagca
    49381 aagcgagagc agaacttaca agtagacttt taaatgaagt caaatttagt gttgttaaag
    49441 ggaatgtatc agaaataaag tttataggtg gctttaatgt aaagggtaaa ggtgtagatt
    49501 catttgatga agaagaagat tctactgaga taataagaaa gattgctgaa aagcttgaat
    49561 gtgtagttgt agcaactgga aaaatagata taataactaa tggtaaaggt acatataaaa
    49621 taaacaatgg aactgataaa ttaaaaggaa ttacaggaac tggatgtatg actgctagct
    49681 tgattgcaag ttttatggct gttactgaga atatattaga agcagcaaca atgggtgttc
    49741 ttacaatgtc tttaagtggg gaattagcta atttaaataa tccaccaata ggtacattta
    49801 aagaaaatct tatgaatgct atttatcaaa tggatataga tactttaagt aaaaattcta
    49861 atattgaatt tttaaattaa taaagagtaa gggagactta aaatgattga taaagaatct
    49921 ttaaaaaaat gtttaaagtt gtatttagta actgactctg aaatgcttaa aggtagagac
    49981 ttttataaat gtcttgaaga tgcaatatct tctggaataa caactgtaca acttagagaa
    50041 aaaaatgctt ctggaagaga gtttttaaga aaagctatga aacttagaga aataactaaa
    50101 agatatggtg ttaagtttat aataaatgat agagtggata tagcacttat ttgtgatgca
    50161 gatggagtac atgtaggaca gagtgacatt gatgttagag aggttagaaa gcttatagga
    50221 aacaataaaa ttctaggagt atcagcaaga actttagaag aagctatttg tgcaaaaaat
    50281 gatggcgcag actatttagg tgtagggtct atattcacaa catctactaa attagatgca
    50341 aaatcagctt cgtttgaaac tgttaaagaa attaaagaaa aagtagacat gccatttgta
    50401 ctaattggag gtataaattt agacaatata gataaactta aatgtttaga aagtgacggg
    50461 tatgctataa tatcagctat attaaaagct gaagatatct ctaaagaagt ggaaaagtgg
    50521 acattaaaaa tataaaattg gctctggtag tgaaaaaaat ggaaaaattt gatataatct
    50581 aagagtaaaa tttaagcaat tataaatgat aaacttttct acatatactt tttaatcaag
    50641 atatatgtag atttggttaa aaaggagcta taaatgatta ggatattgtt agtgtgtgtt
    50701 ggaggcatgt cttctaccct attggtaaat aaaatggaga aggatgcaaa aaaaagaaat
    50761 atagactgta aaatatgggc agttggagaa ggagatataa aatcggagct tgataacttt
    50821 gatattttac ttcttggacc acaacttaga tttatgcttg atgacgtaaa gtctatagtt
    50881 ggagatagag ctccagtatc tataatagat atggtaaact atggcacttg taatggtcat
    50941 gctgtgttaa attcggtttt agaaatatta aaataaataa taaaaatgga ttctatataa
    51001 tagagtccat ttttattatt tgttattaat aggcttaaaa cttagcttac catttctttt
    51061 tttaatctcc acatagcaag tgaaaaactt gaacagcata atattaaaaa tagtaggata
    51121 acaggcatta tatctccaat aagaatagtc tcaccaaata ttaagctacg taaagcgtta
    51181 ataacatggg taaatggatt gagcatcact gctactttta atcctccaga taaactttct
    51241 atagggaaaa gagctgaact taaaaagaaa ataggaagta caattgcagt cataattgtt
    51301 tcataaacta tttcatttgg caataataaa cttatagaat aagctagact tgataaaaag
    51361 aaggctgtca taaatatcag tactatcata agtaggattc caccaatgcc agattctatc
    51421 cttactgaga agaatatact tactatacac aaaatagtta cttctatgaa agaaactaag
    51481 atagcttcta ataattgacc aaggacgatt gaatacctac tgataggtgc aattaagact
    51541 ctatagaaac ttccactgtt cttcattata aagtttataa taccaccact actacaagaa
    51601 gaaaacacaa ccagtacaat gatacctggt agtataaaag cagtataatt attgatattt
    51661 atattattca tagtttggtt tgcaatagaa ctataaagca caagccaaag aaaaggttgt
    51721 aatatagtaa ctacaaatga gattggattt ttaaaacgcc acttcatact acgccataag
    51781 atatttaaca ttcccattcc tcctttaagc tttttttaga acttgtaagt gctaaaaata
    51841 catcttcgag acttggctct acaatttcta ttgcatcaaa ttctatatca tgttctaaaa
    51901 gccatttatt tattaaagta aaagcagttc tactatcgtt tacacttata aaaattgaat
    51961 tttctcgtac gctcataaac tttactaaac cagtactttt aattgcatct ttatattttt
    52021 ttatatcttc agtattatgg aaagttatac gtagtatatt ttgtctaatg taactacgta
    52081 aacttgatgg tgttccttgt gctaaatcct ttccattctt cataatacaa atattatcac
    52141 tcaattgttc agcttcttca agataatgag tagttagaaa tatagttgtg ccatactcat
    52201 ctctaatttt taataacata tcccacatag attttcttga atcgacatcc ataccaacag
    52261 ttggttcatc taaaaatagg attttaggag atgataccat attcatagct atgtccaatc
    52321 tacgttttac accccctgaa tatgatgaag taggatattt taagtaacta gataagtcaa
    52381 acttatcaat taaagagtct attctttgtt ttgcaatctg tggttctact ttatacattt
    52441 tactttgaaa taccatattt tccataaggg ataaatgttc atcaatagag atttgctgtg
    52501 ctacacaagc aatttgagta cgtatccaag aaggattatc tactaaatct tttccaaaca
    52561 ttgttacatt tccagatgta ggtttgtaaa aggtagtcaa aatatttata agagaagatt
    52621 taccagcacc attaggacca agtaaagaaa aaatttctcc agcatttaca ttaaagctta
    52681 gagcatttaa agctttcaca ccatttttat attcttttac taaattgtct atttcaatcg
    52741 ctaacatata ttattcctcc tctttaagtg gaaatattat ctctgtaata tagttatctg
    52801 ggtttccttt tatcaacata cctggtcctt taataaatac ttctctccaa ggagtttgta
    52861 tttttatatt attttcatga atatatttaa atatcatttc atacgttttt ggaaaattac
    52921 tataagagcc tgtgtgagta aaaaataaag cttttgtttt aggaaattct tttgtagtta
    52981 tacccatacg atttggagtt tcagcagttg gaacacataa ttccatttct gcaacaccag
    53041 ttttttggtc aacatcatag tagcaaaaga atggtgcacc gttagacttt ccttttatag
    53101 ctttaaatac atttggaaaa tactttgttg cctcagtcat aggtccatta taacgcatgg
    53161 tagccactgt gactgattcg atatttttga tttcaatttt gcaattcatt gtttacctcc
    53221 taatgtgtgt tcatattctt actagatttt taagcattaa tacatataag attttgatta
    53281 gttgaaaaca tataatctta tctcgtttgc ttgttttcaa gtctaacata acataaaata
    53341 tatatcctct catttgatgc tccattttgt aaagttatta tttaagcttt actttagatt
    53401 ttttagcaaa ttaaaataaa gcaatttata aaataagtat ttacaaatta agtgtattaa
    53461 tcgtataata cacttaatag gatactagat aaagtctgaa ataaaggcgt atttttttaa
    53521 agtaagtgta ctatcgtatt aatacactag aataggagga atcatgaatt ttgaattaga
    53581 taatacaact cccatttatt tgcaaatagt aaagtatata aagagacaaa tagtaacagg
    53641 agagttgaaa ccaggagaga caataccatc aagaagagaa atggcactta atctaaaagt
    53701 aaacttaaat acagttcaaa gagcatataa ggagatgggt gatatgaata taataaatac
    53761 ttttaaaaat tatcaaagca gtgtaacagt tgatgaaaat atattaaaaa atttaaaatt
    53821 agagcttata aatgaatcac tatctgtttt tatagaagat atgaaagcaa taaatgttag
    53881 caaagaagaa gttttaaaaa taatagaaga taagtattag ttttttaaca aatagaaaac
    53941 ttagtttaga aagtttattt ataagcatat tggatgtgga ggatagtaaa tatgatagaa
    54001 ataaagaatg tcagcaaaac atataaaagg atgcaagggc ttaaaataag aaagatagaa
    54061 gctttaaaaa atgtaagttt taatatagaa aagggaaaaa taactgcatt acttggtata
    54121 aatggtgttg gtaaatcaac tatgttaaaa gcaatagcag gacttataaa cattgatagt
    54181 ggagaaattc gtatagatgg agaaaaaata aatgaaaagg tatacaataa attggctttt
    54241 gttccagatg tacaatctca ctttagcaat acaacaataa aagaaacatt tgaatttatg
    54301 gaaatttttt attcaaagtg gaataaagaa aaatcaaaag aaatgatgga catatttaaa
    54361 ttggatgaag atgaaataat tgataacttg tcaaaaggaa acattgcaag agtaaaatta
    54421 atacttggat tttgccaaga cccagagtac atacttcttg atgaaccatt tacaggaatt
    54481 gatttgttta agagggaaga gtttatagga gtaatagcgc aatatatgga ggaaaatcaa
    54541 gccattatca taactactca tgagatagta gagatagaaa gtttagttga tgaggttgta
    54601 attcttgatg aagggcagat tataacttca tttaatgcag aagaattaag agaaagagaa
    54661 ggtaaatcta tattagataa gatgagggag gtatataaga atgaataaac ttctatatct
    54721 aataaatgta gatttgagaa gaagcaataa gttttatata gcttatatat catttttttc
    54781 actaattaca cttagtttaa atttattcga aattaataaa tttaaaaatt ctaaatttat
    54841 tatgaactta gcaatagaag attttggagg tatattttat ggactaggga tacttagtaa
    54901 tcttggtttt atccaaagta tattgttctt tgggatattg ggacttttta tatactatat
    54961 ttttatgtgg aaaagagagt tcttttcaaa taatcaaagt atttatacac ttatgatgtt
    55021 acctcaaaat aagtttaaga tttgtatatc taaatcaata gctttgataa caatgatata
    55081 tggttttttg ataagtcaga cagcaacatt atttatatgt aaatatatat ttaatttcat
    55141 ttttagaaat atgcctataa tcaatatgaa ctttgccaaa gatttatatt atttaaactt
    55201 gaagagtata ccaattgatt ttatctcttt tatggctatc tatgtatttt tactacttat
    55261 agctatttct attgtaaatt gctgtatatt atttatcttt tcctatataa ataaatttta
    55321 tgtaatttta atcactttgc tgattatagc aggcttatat ttttcaacaa tatatataaa
    55381 tataatcact ttatttagaa aatattatag tcttatagga tttcaattta acaatttagt
    55441 agcagggtta ttaagttttt taattataat gtttattcta aatggaatat cttatttgct
    55501 aattaaaaag aaagtatctc tttaaggagg ggtggtatga aattaaaatc taaaatatct
    55561 atacttatta tatttttgac tttagcaata tattttagta taggtttatt aaataatgaa
    55621 gataatttaa agataaaaac tataaaaggt gactctaatg aattagacca tataaacata
    55681 aattttggat atgctttgaa tggatatata aattcatatt atacaataaa tggaagtaac
    55741 aaaaccaaaa agactgaatt aataaaacta caaaaggata gtaagaacac aaataattta
    55801 attgatgtat ctagtggttc agatttaatt gcacatgttg gatttgaaat gaatgaggag
    55861 tcaaaagata taaactttgt aatagatgag aaaaaagaag atttagaaaa aggtgtattt
    55921 ccatcagaag gaagtgataa agaaattgaa tatgaaaaat tagatatgaa taattttaca
    55981 aggacaagat ataaagtaga taaaagtaca gatgattatt atgcaaatat actagcatca
    56041 aaaagatata aaaaatactt atatgtatct gtactttatg ctacaagtga ttcatcagaa
    56101 aataacaaag aatattcaag tactatagat ataataaaaa ttaatccaga aaataaaaaa
    56161 atcaagacta taaaaagtat aaatttaagt aattattttt ccgaaaaata ccaaaacata
    56221 gagaccatag gtgtaagtta tgctagcaaa tatgaggata agatgtatat tttagtaaat
    56281 gtactaaata caaacatagg tgataatagt aattctaaat ttcatttact tgagtataat
    56341 cttgaagaaa ataaggaaag cataatggaa ttaaaaactg atagcaaaat ggctttagca
    56401 aaagcaaagt tagaagctaa taaattatat atggtaatgt cgaatgatta tgataatagt
    56461 tcaattacag agttaaattt acttacctat aatatattag ataaaagctt agatgaagat
    56521 aaatatgttt tagataatag agaaaaaaga ggaattagaa gtattgaaat tgattcaaat
    56581 aaaatcgttg catatacatc aaggctaaac tctatattat cttgggataa taaatttatg
    56641 ctatatataa taaataaaaa ttctaaggaa attgtatatg aaggagaatt acaatttaac
    56701 agttcaaata gtatgttaga atttgaaata aagtaggtga gttgatgaaa gatttaataa
    56761 gattattcga atttgaacta aaaagaaata taaagaatta tatatttata ataatttgtt
    56821 gttgttcttt tgtaatttta aacatagtaa aaaatttaaa tgactataat tacataatag
    56881 aaaatgcagt taaaagtgaa cagttaacaa aaatcggaaa tacgatagaa acggtaaagg
    56941 ttacaggttt ctcaagcttt agaaatataa tgggttctac agaatcgtgg tttatgtttg
    57001 gtataattgc atgtatttgc tatgcttttt ttatttggta tagagacttt aatggtagaa
    57061 gtaaatctat atatacactt ataatgctac ctaaaaatag aatcaatatt tatatatcta
    57121 aattattaaa tatattattt ctagtgtata gctatacagt agtacttaca atatctttgt
    57181 ttattgcaag taagttgttg cctagacata tgcttggtaa tgtcacaaac tatggttttg
    57241 tacaagaaac aatatatgag ttaaaaatgt tacttccata tagctttgaa atactatttg
    57301 tagagtatat atttttattg ataggatttg tatctgtagt atttacatca attcttataa
    57361 ataaatctat ttataaagta agcactttaa taagttttct atttttagtt atagaaattt
    57421 tagtgtttat aatttctata gaatttatta taccctacga atacagtgat gtatttactg
    57481 ttctatattc aagtataaac atatttgtat gtagtcttat atctaataaa cttttgaagc
    57541 aaaagattga cttttaggag ggatattatg aaagcaaaaa atataggaaa atatacaata
    57601 tgttttataa tagtatgttt tttaatgatt actatgacct taatattgag ttattttaat
    57661 aaggataaac tatctgtaaa aactttaaaa ggcaatgtaa aagatatagg gagagtaagt
    57721 gtagtatata cacctaatat aagcaaattt tcttatgagg aggtaattat aagtaaaaat
    57781 ggagtaagaa ataatacaaa cccaaaatca agaattagaa atgattattt aaatattgac
    57841 aaaaaataca gtgactttgt taatgataaa ggaaaagaat ttatatataa agatgatttg
    57901 aatataggag aagcgtatac ctctgttaag tctgatttag tacaaggaat gaatgcttta
    57961 aatgattgta taaaggtttc aaataaaaat ttaaaaagtg gggtagaaga aaattttgat
    58021 attaatttaa ataagtctga ttttaaagaa aatagttgga aaaccttatt taacaaaata
    58081 tataaaggta atttatatat ggtaattagt gaaactaata tttcaggttc taaagtcaat
    58141 aatatttgta tactaaagat agatataaaa aataagtctt ataaattatt aaatagattt
    58201 aatttaggat tacagaatgg agaacaacaa aatatcaatg aaattaaatt ttctattgga
    58261 agtaaattat acttagaaat agtaaataat aaaagtaaaa atggatatat tgaaggacat
    58321 gatagttact ctaactttat tatatatgat atagaagata acacttttaa tataagtaat
    58381 aaatttatgg ataatctaaa caaagaaaag aatgcaaatc caaaggagat tggcttatta
    58441 agtaaaacta agctagatta tatggtaaaa aataataaat tgaatcttat agttacggat
    58501 atgagtaatt ccataactaa tcttgtttat gatattaatt ctaatgagat taaattagaa
    58561 gattatgaga tacttgattt aaaagtagat tataatgaag catcatctgg agttaggaaa
    58621 gttaagctac tggatgataa gatatattct atttcaggta ttaagaacag tatatcagga
    58681 gaattaaaag gatttaaagg gattgttgat gtagtcggaa ctaagccagt aaaatttcaa
    58741 gtatttgata tgaaacttaa aaagaatatt tatgaagctg agctaataaa tggagatata
    58801 agtttacaag aaaagttatt ttttgttgca aattaagtgt tagaattaat tttagaactt
    58861 taaactttta tatgtatcac agataagtat aagtaaggga gtgtctcaaa ataaactttt
    58921 tagctcatga gacacttttt ttatatgaaa tcaaatatat tttcattgtt tagatttatt
    58981 ttgataatga aaaaaagatt atctttattt taagaaagac atttatttat aattatatac
    59041 aaaaatattt tttaatgttt ttgtgtataa ttataacaat ttaatttata ttaatgcact
    59101 taaatttgaa atagaatgct tatagtggta aaattaatta ttagaatatt agaaataata
    59161 aataaataat acattgtact taaaaggggg agaaatttaa gatgaacaaa aaatatatta
    59221 aagcagggaa tttaattgat ggaaccggaa atagtattat gcaaaataag ggtataatta
    59281 ttgatggaga tactatagtt gaaattgaag atataagaga tgatttaaat ggatatgatg
    59341 tgtacgatta cttagataaa actgttatgc caggcattat gaattgtcat gttcacttga
    59401 caatggagcc agttggaaat ccaaagatat attatgataa tgtatcagat gtagagcttg
    59461 tagtaaatac gataaaacaa cttgatgctt atttggattc aggagtaaca tatattagaa
    59521 gcttaggttg tcccaaatat gtggatgtac aacttaaaaa tcttatagac aaagggtcta
    59581 tagatggtcc tggtatagtt acttcaggtc cagttatatg tatgacagga gggcatggat
    59641 attattttgg tattgaaagt gatggagtag atgaatgtag aaaatcagcc agaacagttt
    59701 taaaaaatgg agtagattgt gtaaagataa tggcaactgg aggtgtaaca actgatggag
    59761 ttgagccagg gtcaccacaa ttaactttgg aggaaatgaa ggctgctgta gatgaagcta
    59821 taaaagcagg taaaataact gccacacatg cacaaggaag aactggtata aaaaatgcag
    59881 tgcttgcagg aattacttct atagaacatg gtgtttattt agatgatgaa ataattgatt
    59941 tgatgcttga aagaggaact tacttagttc caactgtggc tgcaccatat tttattctaa
    60001 atgcaggaaa agaaagtgga ataactgaag ctactcttag aaagtgtgag attgttgcca
    60061 ttccacataa agagtcattc ctaaaagcat ataaaaaagg aattaaaatt gcagttggtt
    60121 ctgatgcagg aacttcttat aatgaacatg gaaaaacata ttatgaaatg aaactaatgt
    60181 cagattatgg tatggataat atggatataa tagttgctgc tacaaaaaca gcatctgaac
    60241 ttttaagaat tgataaaaat tatggaactc tagaaaaagg aaagaaagca gatgttatag
    60301 ttgtaaatgg aaatccagta gagaatatag acgtacttgc agatgtgtta gcagtattta
    60361 aacttggtaa aaaagttaga taaatagtat aaaaataaaa aagagtgtct aaagaaattt
    60421 ttaaataatt atagacactc ttttttatta gtaataatta aatcttttat actttagaaa
    60481 atagattcta ttttatattt agatataact ctttaaaatc attcttatgc aatataatct
    60541 atagaatcta cacatacaaa gtatattctt gaatcattag aatttccaag tactataaca
    60601 tcatttttct tacctagaac ttcaacacca gttagaacca aactaccagc tactacagta
    60661 acttgattat ttatatttga catataaaga ttatctagga tacctttatt acaacagcaa
    60721 tcatcacaat cgcagttgca attacattct ttgtaatgtt ttttatcaag atagtaacct
    60781 aaagatgcta tgaaatcttc ataatctgca ggtgtaatat caaatgcaac agctttaaga
    60841 ttacacaatg atgctaaatc tacgtttgct aatggagtag atgcagcaag tataaaatca
    60901 attatagcag caagtattgc atctaatata gccccaaggt ctatcgtagg aggaataact
    60961 gcatcaataa gtgcaattaa ttcagctact cctggtatag ttcctatagt attaattaat
    61021 ccctcaagag ttaaagggac tggaatagga taagatactc taccagctat atctattaaa
    61081 tcacagttac aagcagaaaa tctttcaaaa gtaccatcaa gtccagataa attatctttt
    61141 ggaggagctg aaagatctat acctaccaaa ttagcaccta ctataaagaa atctgagata
    61201 aaagcaaatt gattaaagtt tacaaaaggt cttagagcat catatcttag aagttctaat
    61261 gcttctctca tacttttttt acaacaacat tgttttattt taggttcttt atatttattt
    61321 ggataattat agtatctatc agctacttga taattttcat agtatctttc atttgtattt
    61381 ggataatctt cctcatattc ttgtgtaaat ctaaagtcct ctctacattt attattttcc
    61441 actaaataca ctccttttat attttaattt aaatgtatag ataattaagc ttatctatat
    61501 agtaatatta tatttataat gtaaaaaaat gttacaaaag atattataaa cgaataaaaa
    61561 ataataattt gccagataaa cttgtaaatt tttatgaata atccattcta aaacaaaaaa
    61621 ctgtgtataa aaaaggttta tatgttatat ttatataaat ataacatatg aacgagaaag
    61681 gagtggtttg ataaatgatt gaggtagata aattgtgtaa gtcttttaca agggttgtaa
    61741 aagatgataa gaataaaagt tcaataagaa agctaaagaa agtaaaaact aaaaaagaag
    61801 aattttttgc tgtaaataat gtttcattta aagttatgga aggtgaaatt gttggaatat
    61861 taggtccaaa tggtgcagga aagactacat tacttagaat gttaggtggc atattaacac
    61921 caacatcagg aagtataaat atttctggat atgattattc aatagataga aattcagcaa
    61981 aaaaagaaat aggttatctc tctggaaata caaaactata tggaaggctt tctccgagag
    62041 aacttctaac aacttttgca agtctatatg agatgtcaaa agaagatata gaagaatcaa
    62101 ttgaaaatat tgtaaaaata atggatatga gtgaatttat agataataga attgaaaatc
    62161 tatcaactgg tcagactcaa agaacatcta tagctcgttg tttaatacat tctccaaaag
    62221 tatatatttt tgatgagcca acactaggtc tggatgtttt aagtagtgca tctattatag
    62281 attttatgaa gaatgaaaaa ctaaggggaa aaactgttct ttactcaact cattatatgg
    62341 aagaagcaga aactttatgt gacaagattt ttatgattca caatgggaaa ataattgcat
    62401 caggaacacc acagagttta aaagaggaat ctggagtaaa taatttgaga gatgtattca
    62461 taaaacttgc cagaaaggag gacatttaaa tgagaagtaa gattgtaaaa tacatattta
    62521 aaaaagaaat gttagacata ttgagagata aaaagacttt atttatgatg attgttgtgc
    62581 cacttctttt atatccttta cttatgttat taatgattca agtaatgaat atgtctgcaa
    62641 gtagtatgaa tagtaaggac attaatatag cttttaataa taaacctaat aaggttttag
    62701 tatccatgat tgaagatgat aatttagaaa aagatactaa aaatacttca aatgataaag
    62761 gcaaaataag agtgttagat gtagataact ataaaaagtc attagaagaa aataaaattg
    62821 atgcttatat aaagatggaa gaaaaaaaat catctataaa ttatcaaata tatataaatt
    62881 cttctcaaga aaattcttct aatgcactaa aaagaattga aactgttttg gataaatata
    62941 aaagatttac catagaaaaa actttatctg aaaaaggatt agatgtacaa gctactttag
    63001 aaccaataac atatagcact gtagatgttg caaagacgga agaagtggca ggatactttt
    63061 taggtcagat acttccattt atattaataa taggagtttt actaggttca atatatccag
    63121 caatagatgt tatggctgga gaaaaggaaa gaggtacatt agaaacatta tttacactgc
    63181 caatatcaaa cttagaactg gttatgggaa aatatatggc agtttctctt agtgcaatag
    63241 taacagcaat tttaaacatt ttatctatgg gactgactat ggcatttatt ttagttagtg
    63301 gaggtattag tagccaattt ggctttggaa actttaatta tggagactta gtcttaccaa
    63361 ttataactac tttaatttgc atatgtcttt tttcaatggt agtttcagca ataagtatgt
    63421 gtgtatgttc attagcaaaa agttttaaag atgctcaaaa ctacataaca cctcttatgt
    63481 taattattat gataccatca tatgtttcta tgataccaaa tatagtatta gatagagtga
    63541 cagctgtaat acctgtagta aatatatctt tacttataaa aagtgtatta tcttttaaaa
    63601 gcgatttaaa tttaatagcc ttagttttag catcaaatgt agcctttgtt atattggcaa
    63661 tcatactact gtctaagatg ttcaattctg aggaaatact ttttggtaat agtaagagtt
    63721 tctctttctt agagaaaaga agtaatataa aaaaagggtc tataccaact gtaagtgatg
    63781 gtgttatttt atatgcagta ggattagttc tattgattta tgttggttct ttagttcaaa
    63841 ttaaatttgg tatggcaggt attataatga cacaattcat gataatttct ttaccgttat
    63901 tatttgcata ctatattaaa gctgatttta aagaggtatt tagcttgaaa gttcccaaat
    63961 taaagcatgt gtttgggagc attgttcttt ggattggtgg atacatactt attatgatta
    64021 taacacagct aattttattc ttatttcctc aaaatatgga agttgctgaa agtttaaata
    64081 aggctctttt tatcaaagat agtgttttac tgaatttact agcaatagct ttattaccag
    64141 ctttatgtga agaaatgttt tttaggggat ttatattttc ttcatttagt aaatcaaaag
    64201 ataaaaataa gtctatcaag ctagctataa tatgcagtgg ggtactattt ggtattatgc
    64261 atatggattt tattagaata attccaacat caatattagg tattatattt gcatatagtg
    64321 tgtataaatc tggttcaata tttgtatcaa tgttattgca ttttttaaat aatagtgtag
    64381 cagttgtgtt aaatcattat acaactggaa atataaccaa cttatataaa tttgttgaag
    64441 ttgatttttc gaacttaaat gtacttaaat ttgccttaat tcttctaata agtcttatat
    64501 taattatgtt aggattaaga gttttagata gaaagtcttt aagaaattaa gtataaagtt
    64561 attatataga ttaaaatatt aataagcact aaagtatatg gatatatctt gtatataaaa
    64621 atactttagt gctattttat atattttaat tatatgaatt atttatcgtt tcatttatgt
    64681 aatgaaaatg ttatataaat gaaacaataa ataattttta ttttag
//
LOCUS       DAMKNB010000013        64259 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.013, whole genome shotgun sequence.
ACCESSION   DAMKNB010000013 DAMKNB010000000
VERSION     DAMKNB010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 64259)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 64259)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..64259
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.013"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            126..1322
                     /locus_tag="PC494_000975"
     CDS             126..1322
                     /locus_tag="PC494_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HDF3911496.1"
                     /translation="MKILVLNCGSSSLKYQLIDMNNEEVLCIGLVERIGIEGSILKHE
                     KAGRDDKYVVEQPMKDHKDAIALVLEAVAHPEFGAVKEMKEIDAVGHRVVHAGEKFAT
                     SVVITPEVEEALKECIDLAPLHNPANIMGIDACKAILPDVPMVGVFDTAFHQTMPKSS
                     YLYGLPHELYTKYGVRRYGFHGTSHNYVSQRAAEILGKDIKDLKIVTCHLGNGASIAA
                     VDGGKCVDTSMGFTPLEGLIMGTRCGDIDPAILPFLMRKEGLDADGLDKLMNKESGVY
                     GMTGISSDFRDIEDAAKNGDERAQATLEAYVKKVQKYIGAYAAEMNGLDVVVFTAGVG
                     ENGKAIRADIASNMEFLGMKLDKEANDVRGKETVISTADSKVKMLLIPTNEELMIARD
                     TLRLVK"
     gene            1415..1939
                     /locus_tag="PC494_000976"
     CDS             1415..1939
                     /locus_tag="PC494_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HDF3911497.1"
                     /translation="MKVSIEKINRKETDKIDLNFCEKIDTISYCDEIYKLVSPVNLKG
                     KVSKTNKGLYLDIDVNFTIVDNCSRCLKEVEIPLEYSIQGFLVKEEDYDEDEFEEFDP
                     FIFDGEEIDLIDIIEQTLDFNVPHKVLCSENCKGLCQVCGANLNEEECSCSEITNDEE
                     YIDPRFAKLKDLFN"
     gene            1964..2140
                     /gene="rpmF"
                     /locus_tag="PC494_000977"
     CDS             1964..2140
                     /gene="rpmF"
                     /locus_tag="PC494_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HDF3911498.1"
                     /translation="MAVPKRKTSKSNTKMRRAANSKMEATGFVSCPQCHEPKLPHRVC
                     PDCGYYKGKEVVSK"
     gene            2347..2904
                     /gene="fapR"
                     /locus_tag="PC494_000978"
     CDS             2347..2904
                     /gene="fapR"
                     /locus_tag="PC494_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription factor FapR"
                     /protein_id="HDF3911499.1"
                     /translation="MKKKSKAQRQKELIDMLKTDPFYTDEELSSLFDVSIQTIRLDRM
                     SLNIPELRERVKSIAETQSSKVKTLGVKEITGEIIDLSVGRLGISMLEVTQDMIYSKT
                     NTLKDTYIFSLADSLAMAIIDAPKVIMRVANVKSFKLIEQQDRLIAKAEVYRNIDKKH
                     YVKVVINNKAQEQIFRGKFIFEELD"
     gene            2915..3937
                     /gene="plsX"
                     /locus_tag="PC494_000979"
     CDS             2915..3937
                     /gene="plsX"
                     /locus_tag="PC494_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HDF3911500.1"
                     /translation="MKIVIDGMGGDNAPKSNVEGAVNAIKEYQVDLIITGDKDLLEKE
                     FSNYEFDRNKLEIVHTTEIIENEDKPVKAIRSKKDSSMVVALNLVKEGKADAIISAGN
                     TGALLAGGLFVVGRIKGIDRPCLCSAIPNVKRGMTLIADCGANADCKPKNLVEFAAMS
                     NIYSRKVLGLENPKVALANVGLEEGKGNDLVKRSYEEIKKLDLNFIGNVEAREVINAY
                     TDIIICDGFTGNILLKSAEGVALSVMSLIKETFMASTKSKIGALLIKDDLRKLKSFID
                     YSEYGGAPLLGLNGGVIKAHGSSDAKAIKNAINQGIKFSKGKVVEDINQFISKYNEEN
                     KNNEDE"
     gene            3963..4949
                     /locus_tag="PC494_000980"
     CDS             3963..4949
                     /locus_tag="PC494_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HDF3911501.1"
                     /translation="MNTKAGILGVGSYLPEQSYDNFHFEKIMDTSDEWISTRTGIKER
                     RFAKESEATSDLASKAALKAIECAKLNVEDIELIILATITPDMSLPSTACIVQDAIGA
                     VNATAFDISAACSGFVYGVTIAKQFVETGCYKNVLVIGAETCSKFLNYDDRTTAVLFG
                     DGAGAAVIGPVNEGGILSTHMGSDGKGKDCLKVPAGGSRLKASKETVEANLHTIEMAG
                     SDVFKFAVRKMAETSLRALEKANLNTTDIDYLVPHQANIRIIQASSKRLELDMKKVYV
                     NIDKYGNMSAASIPVALDEAYREGKIKKGDNVVLVGFGGGLTWGASVVKWTL"
     gene            5058..5987
                     /gene="fabK"
                     /locus_tag="PC494_000981"
     CDS             5058..5987
                     /gene="fabK"
                     /locus_tag="PC494_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-[acyl-carrier-protein] reductase FabK"
                     /protein_id="HDF3911502.1"
                     /translation="MNKICKILNIKYPVIQGGMAWVATASLASAVSNAGGLGIIAAGN
                     APKEAIKKEIVECKKLTDKPFGVNVMLMSPFVDDIIDLIIEEKVQVITTGAGNPAKYM
                     DRLKEAGTKVIPVVPTIALAQRMEKLGATAVIAEGTEGGGHIGELTTMVLVPQVADAV
                     NIPVIAAGGIVDGRGIAASFALGASAVQVGTRFICSEECSVHSNYKNLVLKAKDRDAI
                     VTGRSTGHPVRTLKNKLSKEFLKMEQNGATPEELDKKGTGALRFATVDGDIEKGSFMA
                     GQSAAMVKEITPCKEIIEAMVNQAREIMPAIEL"
     gene            6003..6953
                     /gene="fabD"
                     /locus_tag="PC494_000982"
     CDS             6003..6953
                     /gene="fabD"
                     /locus_tag="PC494_000982"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HDF3911503.1"
                     /translation="MGKVALVFPGQGAQYVGMAKDLYENNTVAKSVIDEASDALNMDL
                     KNLMFNGNEEELSKTENTQPAMVTHSVAVLKAVQAQIDLKYNACLGLSLGEYSALVAA
                     DAIDFKDAVCLVKKRGKFMQETVPAGVGAMAAILGLDRNVLENVVKDIQGGIVEVANY
                     NSPGQIVISGENEKIEEAMVKCKEAGAKRAVKLNVSGPFHSSMLKEAGVKLASELEKV
                     NITKPKVDVVANVNADYYKNEGKDLLIKQVSSSVLWEDSIERLLNDGYDTFIEMGPGK
                     TLKAFIKKIASNKKANVNIYNIDGIDSLNEFVQNYRNGEI"
     gene            6953..7702
                     /gene="fabG"
                     /locus_tag="PC494_000983"
     CDS             6953..7702
                     /gene="fabG"
                     /locus_tag="PC494_000983"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HDF3911504.1"
                     /translation="MINLTGQVAVVTGGSRGIGKEIAKKLASFGADVVINYTSKEDEA
                     LKTKNEIESMGVKCTSIKCDVSKFDEVNQMIDSVVSEFGKIDILVNNAGITKDGLLMR
                     MKEEDFDRVIDINLKGVFNCTKAVTKPMMKKKYGRIINMTSVVGIMGNAGQTNYCASK
                     AGVIGFTKASARELASRNININAVAPGFIETDMTKVLSDDVKESTLANIPKKSYGKPE
                     DVANAVAFLVSDMSSYITGQVINVDGGMVMQ"
     gene            7756..7980
                     /gene="acpP"
                     /locus_tag="PC494_000984"
     CDS             7756..7980
                     /gene="acpP"
                     /locus_tag="PC494_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HDF3911505.1"
                     /translation="MFNKVVEIIIEQLGVEDKEITMETSLMKDLEADSLDAVEIIMAL
                     EDEFGIEIPDTEAENFKSIGDIVKYIEANK"
     gene            8009..9247
                     /gene="fabF"
                     /locus_tag="PC494_000985"
     CDS             8009..9247
                     /gene="fabF"
                     /locus_tag="PC494_000985"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HDF3911506.1"
                     /translation="MNKRVVITGLGCVTPLGTGKEEFWSNIKSGVSGIDKITNFDAST
                     YQTQIAGEVKNFHPEEYISKKELKRLDKFAQFAIVSAKLAVEDANLDLDKVDRERFGV
                     IIGSGIGGVEAIETQHKILLEKGNKRVSSLFVPMMIGNMAAGQVSIFLGAKGPNTNVC
                     TACASGTHSIGDAFKVIQRGDADIMVAGGSEAAVTGLAFAGFCNMKAMSTRNDDPKTA
                     SRPFDKDRDGFVMGEGAGIVILEDLEHALARGAKIYAEVVGYGLTADAYHMTTPAENG
                     EGAARSMNMALKDGNVPLEEVDYINAHGTSTYYNDLYETMAIKTVFGEKAYDLCVSST
                     KSMTGHLLGASGAIEAVVCAMSIEDSFVPPTINIQEVGEDLDLDYVPNQGKEKNIRYA
                     LSNSLGFGGHNATIVLKKYV"
     gene            9473..11191
                     /locus_tag="PC494_000986"
     CDS             9473..11191
                     /locus_tag="PC494_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HDF3911507.1"
                     /translation="MNFRLPKKRLPKKIIFICIILISIILFIKYDQNGLKEREIINKG
                     KYMSESLVADKEYDEAKKVVKTSFESIPEKKYNKVYNEVWDMLKTISYVPDGTKIVID
                     SLEKMRESDVKLSDECRFNIEKRLASVYIMDNNYSKAVDLTVKSIKLAEKLGNNYEKA
                     RLDVDLASIFLKIGGYETGEKLIKDSFKIDIDEGEKNGMVRLYAIINLAEIYVEEGEY
                     DKAIEISSRIKDYKKFVNTDNYNDFDIMASIMQSNAYVGKNNIQKAKTLLEKADYLIK
                     SDRTVYILDKDMYYYMAMGNLEYKSENYNSAIDNYKKSLEISTKRKLTQEKIKNLNKI
                     LNIYEKQGNIESLNEYQKMLINEYKENKSIRDSETSFYIIDKVSNESKLFEKTKKEIK
                     YYKILFTVILIAILGSTFLYNRLKYFKAQNLHDGLTNVYNRKSFDIMYEKYREKDDNF
                     ALVMIDIDNFKLINDNYGHKFGDTVIKGITNTICVMLEQDDKVFRYGGEEFSVLIRNK
                     SGEEVADIIDSIRVAIANKKWNDDVTVTISAGVAHISDSKDVLEEADKNLYKAKQLGR
                     NKVVYK"
     gene            11222..13222
                     /locus_tag="PC494_000987"
     CDS             11222..13222
                     /locus_tag="PC494_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDF3911508.1"
                     /translation="MKQSIAIVTDKITKLSSFLEENIRLVLGNYIDINHYYLEVLKEN
                     DKIQGDFVLVMNDDRLNSMRKHLVQDSKIIVIRRTLKENEIYGLFSIPNGTEVLVVND
                     TKETTLETISLFYKIGVKNLKFTPYIEGKIYKNIDIAITPGVKGKVPSYINKVIDLGN
                     RYIDISTFIEIINGLRIDVKEIRKNLMAYSESLISLDNGVKDNYRQLFLKIEEQDVIL
                     NLSKDGIIFTSADGIINTFNKEALKILGINENPQGKNIEDIISEDLNILLEDKEIIDE
                     VVFTNKKYINVNKKSIFSMGNKAGIYYNLQEITYIKKLEQNLTNKLREQGQIARYAFK
                     DIKTKNKNMVKCVELAKKISKSDLSVLIIGESGTGKELLSQSIHNASNRSNQPFIAVN
                     CAAVPDSLLESQLFGYEKGSFTGALREGKKGLFELANNGTIFLDEIGDMPPLLQTKLL
                     RVLQEKQVMPIGSHNVINIDVRVIAATNKNLLKMIREGKFREDLYYRLNVLPIDVPSL
                     RNRKEDIITLMNFFLKNNIRLSPEVITILEKYNWPGNIRELQNVASYVSLMCDSMVFR
                     DDLPPYIRVECANNYEDGFGYTRKEFEEILRILYERRESSSGIGRGFIIEKLIQEGIE
                     ISESKVRKVLSYLSECGYISSKSGRGGSQITSEGIKLYNNIN"
     gene            13573..13818
                     /locus_tag="PC494_000988"
     CDS             13573..13818
                     /locus_tag="PC494_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03905 family TSCPD domain-containing
                     protein"
                     /protein_id="HDF3911509.1"
                     /translation="MKYKTTGTCATEIEFEVKENKVTNVNFIGGCDGNLKGLKVLVEG
                     MNIEDVIQKLKGIECKTKPTSCPDQLSLALENYMNIK"
     gene            13853..14578
                     /locus_tag="PC494_000989"
     CDS             13853..14578
                     /locus_tag="PC494_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HDF3911510.1"
                     /translation="MKPIIGILGNLIIMENGMFPGLERSYVNNDYINAVLKGGGSPVI
                     IPVNTDKEVIKKQIEMVDGVLISGGWDINPQLYGEETREETTFIYPEVDEFDLIAISI
                     ALELKKPILGVCRGLQILNVSLGGTLYQDNNLIEGSYIKHTQSSKRHVATHKVDVKEG
                     SILEGILGKQLLTNSYHHQSVNQLGKGLKAIAYSKDGIIEAIEKEDENFVVGVQWHPE
                     MMVDYCDKMEKLFKYFINICSNL"
     gene            14600..15913
                     /locus_tag="PC494_000990"
     CDS             14600..15913
                     /locus_tag="PC494_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HDF3911511.1"
                     /translation="MNEKNKMGLISIILLGINAVVGAGVFLLPGDAMKSFGVASIFVY
                     IFDMLLVLSMAFCFAEVAGKFNKNGAAYVYTKEAFGDFCGFEVGLMKWVIGCISWGAL
                     IVGFPTSLSAVWAPAGEPHIQKIIIVAMIVGLTIINLLGVSLSKIVQNVITVGKLIPL
                     ILFIGIGIFFIKGVNFTSSTMVPPGAGATEFGAAALLMFYSFTGFESIAVAAEDMENP
                     QKNIPIAIISVIVIASIIYILNQVVCVGILGDSLSSTSTPVADAARICFGNMGAGLVT
                     FGTLVSVGGICMCGAFVNPRSCVALADDKMLPRIFARKDKKGTPYVAIIATMLITIPI
                     ALSGSFAELAAISAVARFIQYIPTSLSVLVFRKKRPELVGTFKTPFGAVIPLIAVCVG
                     TWLLFQASMHQLIMGLGALAIGVPLYFIMKSYNRKVYGENLKKIV"
     gene            16119..16658
                     /locus_tag="PC494_000991"
     CDS             16119..16658
                     /locus_tag="PC494_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDF3911512.1"
                     /translation="MPTITLKNGVDVLIREGVREDAQSIIDFYNEVGGETHFLSFGKD
                     EYKISLEEQENAIESAKASDNSVKLIAFIDGEIVGIATIDSNQKAKGKHVGVLGIVVK
                     EKYWGIGLGKRLMLDLIEWCKSNGITKKITLVTNEENYNAIGLYKKVGFEVESILKKE
                     CYYNGVYTDLIGMSLLLGI"
     gene            16747..18732
                     /locus_tag="PC494_000992"
     CDS             16747..18732
                     /locus_tag="PC494_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-1,6-bisphosphatase"
                     /protein_id="HDF3911513.1"
                     /translation="MKNLCKISDDYLNSKLKYLKLLSKQYPSISKASTEIINLEAILN
                     LPKGTEHFITDVHGEYEPFVHVLKNGSGVIKRKIEELFSNTIRDSEKKMLATLVYYPE
                     QKLDLIIKQEENIDDFYRINIYRLIELCKYASSKYTRSKVRKLLPENFKYIIEELLHE
                     HVKSEHKEEYYKSIVETIVDIGIAKEFIIAISTVIQKLVVDRLHVIGDIYDRGPRPDI
                     IVDKLIEHHCVDIQWGNHDILWMGAASGEKTCIANALRISARYANLDIVEDIYGINLL
                     PLATFAIEMYKDDPCKEFIPKVNDQSVTTTEKSLMAKMHKAISIIQFKLEGEVIRRRP
                     EFEMEHRLLLNMINYDEGTINLKGKTYKLKDTYLPTIDKKDPYKLTMEERNVIDKLVS
                     SFRGSEKLQKHVSFLFSKGSIYLKANSNLLIHGCVPLNEDGSFMSMNIMGKEYKGKAL
                     MDKMESLAREGFFFKDKAEEKLYGMDIMWYLWTGKCSSLFGKDDMTTFERYFIAEKET
                     HKENKNPYFKLRENEMACKRLFEEFDLELDESHIINGHVPVESKNGESPIKANGKILV
                     IDGGFSRAYQKTTGIAGYTLIYNSRTLQLVSHEPFNSAEEAIANESDILSTTVVVEHK
                     AKRKMVRDTDEGVKIQEEIEDLKLLLMAYKKGLIKEM"
     gene            18956..19924
                     /gene="spoIIIAA"
                     /locus_tag="PC494_000993"
     CDS             18956..19924
                     /gene="spoIIIAA"
                     /locus_tag="PC494_000993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AA"
                     /protein_id="HDF3911514.1"
                     /translation="MNKLSDEIINSLSTTIREKVEKVSNNNLNIEEIRLRSQKPLILN
                     ANSKDYFYNQKTMTLDLNQQNSYVVTREDVEQTFQIICKYSIHSFMDDIKKGFITLRG
                     GHRVGLVGKAIVEDGQVKNIKHISSLNIRVSREIIGCSDKILSHIIKGKNQINNTLII
                     SPPQCGKTTLIRDIVRNLSNGNEDYGFKGLKVALVDERNEIAGAYLGVPQMDVGIRTD
                     IIETCPKDLGITMLLRSMSPNVIVTDEIGSEKEIKALYTALNGGIGLITTVHGDSIED
                     IQNRKELNRLLDKELFKKVIILSAKRGAGTIEKIYDLEEKRWYFAN"
     gene            19914..20435
                     /locus_tag="PC494_000994"
     CDS             19914..20435
                     /locus_tag="PC494_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AB"
                     /protein_id="HDF3911515.1"
                     /translation="MQIKIIIIAFLIGSSYLIGEQIYKTYTRRHKQLNDLIRVLEILR
                     MDLSFGLYTLEEIFNRIGGNKEFCFWKFFYQISEGLHNEQSKTLEIIISENIDVLSKE
                     TYLGNKEIEELKNLILTLGKSDIESQQRMIDLSIENLKKQTYETKEDINKKGVLYKKL
                     VTFIGIGICIILI"
     gene            20452..20649
                     /gene="spoIIIAC"
                     /locus_tag="PC494_000995"
     CDS             20452..20649
                     /gene="spoIIIAC"
                     /locus_tag="PC494_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018589775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AC"
                     /protein_id="HDF3911516.1"
                     /translation="MEISLILKVAGVGILISVLNMILEKTDRKDWAGLTTLAGVIIVL
                     GMVITEISDLFNTVRTMFQLY"
     gene            20665..21051
                     /gene="spoIIIAD"
                     /locus_tag="PC494_000996"
     CDS             20665..21051
                     /gene="spoIIIAD"
                     /locus_tag="PC494_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AD"
                     /protein_id="HDF3911517.1"
                     /translation="MEIMQLIGIAIISTTLCLVIKKDRPEIANFIAIITGVIILLSVM
                     FKLNFIVDSIQDLANKANIPTMYISLIIKLIGIAYLMEFAIQLCKDCGEGNIASKLEF
                     GGKIIVMSMSFPILLSIVEMVVNIIP"
     gene            21136..22341
                     /gene="spoIIIAE"
                     /locus_tag="PC494_000997"
     CDS             21136..22341
                     /gene="spoIIIAE"
                     /locus_tag="PC494_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AE"
                     /protein_id="HDF3911518.1"
                     /translation="MKKRFLPMIIGFLFTFFFVNIFAIMIFANEVPSSEDKEYGETKN
                     SIDKYIDGQLDKLDINEIQDYINKEIVINDVNLKSFVKDLISGEKNILDLFNKDGLKI
                     LMFDEFKASLKVVAVILVLALLSSILKSLENSFSSGAVSQIATYIIFITMVSLTLIGF
                     KDVLQICYDAIDHTVGLMQVIMPILITFLLLIGFPITSTTLNPIFIGGVTFINVFFKN
                     FLFVSITVAFGILIINNLSKNIRLKRFFSFVKQINYVSIGAMFTVYLGLVSIQGLYVT
                     SFDKFSVKTAKFAIGNFIPVVGGFVSDSVDILLSSSQLIKNIFGGIGLILLVGICLLP
                     VIKILSVIVVYKLAAIIVEPVGEDGISNFLNEVANLMIIMLASVIAITVMFFVTVAIL
                     TSISVVSQG"
     gene            22401..23018
                     /locus_tag="PC494_000998"
     CDS             22401..23018
                     /locus_tag="PC494_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AF"
                     /protein_id="HDF3911519.1"
                     /translation="MLEGIKAWIVSVLIGAFIVNIVDMILPSSKIKPYVNLVLNFMFV
                     FIVITPVVGFFSKDMSLEDRILKSMGNYNKQYVDSTNALAKETGNNSLSKGYEDGLKE
                     VLKLKLDEYGYDLEDIELNGANINNIKIKEKNNSAKSNNSSNEENKNNSTKREEENIN
                     SNDKENSKQVFKKGTEYGLNLNEEKLKNDLIKVLDVSIEDIQIDK"
     gene            23030..23584
                     /locus_tag="PC494_000999"
     CDS             23030..23584
                     /locus_tag="PC494_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AG"
                     /protein_id="HDF3911520.1"
                     /translation="MLKNLNDKDKRKVYSLITIAGICVVSLVLLSCFPSSKSDKQVGK
                     TETNKNAEKQVTKEQEKDDLESKLTAILSKIDGAGDVDVMVTFESSEEIQPAFNSNNT
                     TETTEEKDAQGGERTVTTSSENKTMITSNSSDPVVIKTTEPKIKGVIVVASGASDPSV
                     KETLYSAVQTSLQVAGHQVEIYSK"
     gene            23611..24300
                     /locus_tag="PC494_001000"
     CDS             23611..24300
                     /locus_tag="PC494_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpoIIIAH-like family protein"
                     /protein_id="HDF3911521.1"
                     /translation="MKFNYKGRGFVIITLTAMLVVVGTVNYQLSKKSLLETSKEFKAY
                     EEAQLQKNTDESDSSKTEDSSNIDKQDGKESADIDIVDSKASKVKEKATETSKEIKAQ
                     LSSEKNMKKASYILDMKMNREKQRNELVQDLNEMINNPSTTEESRKEASNMKLNIVKI
                     QEKELQIENLLSTKGYEEALVYISDNKVNVVVNEAKLEKKDAAKIFDLVAEQANVKYE
                     NIKLTNNNSNK"
     gene            24410..24772
                     /locus_tag="PC494_001001"
     CDS             24410..24772
                     /locus_tag="PC494_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HDF3911522.1"
                     /translation="MEDNKFGQVKISNDVIATIAGLAALEVEGIETTATLTDKLLKNN
                     GVKIQIEEEDVNLDVMVTIKYGMSIPDTAFKVQENVKNTVETMTGLKVSQVNIHIQGI
                     SFKKDKVDKEEAKATKKN"
     gene            24857..25363
                     /gene="nusB"
                     /locus_tag="PC494_001002"
     CDS             24857..25363
                     /gene="nusB"
                     /locus_tag="PC494_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HDF3911523.1"
                     /translation="MKKDRAQKSTTREYIMKLIYQININKEDFETLEDKVDNFLKDNS
                     EHIINRYKELALQYSKNTNLKLEDTEIEDVIDKKYINTVCKALKENHDKIDELINKHA
                     KNWTVDRMPKVDVSILRLSVCEILYLDTPNKVSINEAVELAKIYCDDKSPKFINGILG
                     SVVDEIGK"
     gene            25347..26417
                     /locus_tag="PC494_001003"
     CDS             25347..26417
                     /locus_tag="PC494_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-sialoglycoprotein endopeptidase"
                     /protein_id="HDF3911524.1"
                     /translation="MKLGNNIIIGIDTSCYTTSIAAISLDKKVIFNEKIMLEVRDNSK
                     GLRQSEAVFQHINNLGILSDRIKSFKDKFNVEGVCSSKKPRPVENSYMPVFNVGHNFG
                     KLLSSIYGCRFYETTHQENHIEASLLNSKLKNNNKFISVHMSGGTTEILLTSKQDSHH
                     NVCDTNLGKIAKISIKKDDKSKLYNNFGYNIDIIGGSKDISFGQLIDRVGIKLGYKFP
                     SGKYLDENALNCNLKIESGLKTSVRDGYMNLSGLENQVNKIINDNGYNTNQKEYISKL
                     VLDSVVRNMFKSLVYLCETYNVNEVVFAGGVSASKYILRELSVKLRKKHIEAYFTEPQ
                     YSTDNAVGCAIIGLNNFLGERV"
     gene            26414..27619
                     /locus_tag="PC494_001004"
     CDS             26414..27619
                     /locus_tag="PC494_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HDF3911525.1"
                     /translation="MKLRALDISEANSYIKRILINDPILSNLKVKGEISNFKVHSSGN
                     VYLSLKDETSKLNCVIFKSNFNRNLKLDNGVKIIANGYISVYERDGAYQLYINEIEIE
                     GIGNLHIEFNRLKEKLNKEGLFDPKYKIPIPKMPNSIGVITSPTGAVIRDIINVIKRR
                     YPKVNIKLYPVTVQGDKSAEEICEAIRFFNHMKNVDTLIVGRGGGSIEELWSFNDEMV
                     AREVFNSQIPIISAVGHETDFTICDFVSDMRAPTPSAAAEIATPSLDDINYKLGNIKS
                     RMSKSLTNQIELDQYRLETVFNKINNYLDSYTIKDKVIQLDKIYDKIIFGIENNLKLE
                     DEKLVKIGALLHNLSPLATMDRGYSITQKNGKVINSIKGLKIKDSIDIVLKDGNLECM
                     IDKIENKEG"
     gene            27621..27836
                     /gene="xseB"
                     /locus_tag="PC494_001005"
     CDS             27621..27836
                     /gene="xseB"
                     /locus_tag="PC494_001005"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HDF3911526.1"
                     /translation="MNLTYEEAYKRLESILSELESKNASLDESLSLYEEGISLYKHCN
                     KLLDDAKLKISKFNQLGIEEDFKIEEE"
     gene            27839..28726
                     /locus_tag="PC494_001006"
     CDS             27839..28726
                     /locus_tag="PC494_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HDF3911527.1"
                     /translation="MEFKQCLKEKASFVEKVLKEYMPKEEGYQKTVIEAMNYSLSAGG
                     KRLRPILTLEACKIVGGNEDEAIPFAIAIEMIHTYSLIHDDLPALDNDDLRRGRPTNH
                     KVYGEAMGILAGDALLNYAFEVMLAGSINKENPEKYLKAINEIAKGAGIYGMIGGQVV
                     DVESENKQIEKEKLDYIHMNKTAAMMVGCMRAGATIGGANSEQMEEITKYAKNIGLSF
                     QIVDDILDIVGDEAKLGKKVGSDIENHKSTYPSLLGLDKSKEIAHNLIDEAKKSIEKL
                     SDDVDFLKGLAEYIIDREY"
     gene            28756..29193
                     /locus_tag="PC494_001007"
     CDS             28756..29193
                     /locus_tag="PC494_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="divergent PAP2 family protein"
                     /protein_id="HDF3911528.1"
                     /translation="MDFFSEIFNNGALGISLIACFLAQFIKIFTGKEKRIELSRILIS
                     GGMPSSHSSFVTSLATVVGIEKGFNSTDFAIITVLALIIMYDAAGVRRAVGKQATILN
                     QMVADIQHGKHIEQKKLKELIGHTPLEVWFGALLGIVTALILM"
     gene            29227..31092
                     /locus_tag="PC494_001008"
     CDS             29227..31092
                     /locus_tag="PC494_001008"
                     /EC_number="2.2.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="HDF3911529.1"
                     /translation="MYKYLDKVNSPKDIKNMSIEEMDLLAKDIRKFLVKSVSKTGGHL
                     ASNLGVVELTLALHKVFDSPKDKIVWDVGHQSYVHKIVTGRKDCFVSLRQFNGLSGFP
                     KENESPHDIFDTGHSSTSISIATGIACARDIKKENYSVISVIGDGSITGGMALEALNQ
                     LGYIDTNMIVILNDNEMSIDKNVGGMSKYLSSIIRNSTVEKMTDEVDKILNVTQTGEI
                     LSKTAHRFKDKLMYSFSPQDCSFFDSLGIRYYGPIDGHNTKELIDILRKAKHKKGPVL
                     LHVITKKGKGYRFAEEQPDKYHGVSKFDIKTGVTSAKVKSMSISVGEKLVDMANSNEN
                     IVAITAAMPSGTGLNLFESAYPKRYYDVGIAEQHATGFAAGLAKNGMKPYFAVYSSFL
                     QRAYDQVIHDVCITKKPVTFLIDRAGLVGNDGETHHGMFDLSYLNSIPNIVVMAPKDT
                     REMELMMDLSLKLDCPLAIRYPRGSSYYLDKGEYGEIVLGKYEVLDDGQDTVILCIGS
                     MVKHALEAKEILSREGINPTIVNARFLKPIDEGMLKALLKNHKNVVTIEDNIVTGGFG
                     SRINKFIIDNEYNVNILNIAIPEEFVKHGNIDELYDFVGLSPKSIADKIRKLVIE"
     gene            31225..32037
                     /locus_tag="PC494_001009"
     CDS             31225..32037
                     /locus_tag="PC494_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family rRNA
                     (cytidine-2'-O)-methyltransferase"
                     /protein_id="HDF3911530.1"
                     /translation="MKKRIDLLLVEQGYFESRERAKKAIMAGLVFVDNQRCDKAGTEV
                     KEDCSIEVKGNPIPYVSRGGLKLEKAMKNFDLTIDGKVCMDIGASTGGFTDCMLKNGA
                     IKVFSIDVGYGQLAWKLRQDDRVVCMERTNIRNVTIEDTKQFADFASIDVSFISLKLV
                     LPKAKELVRHDGEVVALIKPQFEAGREKVGKKGVVREKSTHIEVIKMISDFSVENGFE
                     ILGLDFSPIKGPEGNIEYLIHLRNGNEGYEFDGETYNNKIVEVVEASHNLDK"
     gene            32057..33736
                     /gene="recN"
                     /locus_tag="PC494_001010"
     CDS             32057..33736
                     /gene="recN"
                     /locus_tag="PC494_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HDF3911531.1"
                     /translation="MILELYMKNCALVEELRLNIDKNLNILTGETGSGKSIIIDALGL
                     CLGDKYDRSFLRKGTDKGLVEAVFFSDNRYLKKILEENDISMEDDNLLVITRLIYSDG
                     KSTARVNGRTVKVSLLKEIASTLIDIHGQHQNQALFNKDTHLKFLDLFGENELEEFKI
                     AYKNVYHKYSEVKKALNCLTENKDEMQIQREIDLLRFQINEIEAANLNKNEYEDLLKQ
                     REVYRNSEKIYNNLNSSYSKLHNGEYNVIDLIGLASKELNDISKYDSVLSEYSDTVER
                     IMYELQDISGEIRNYKDNIDFEPYELEQIELRIDEINNLRRKYGDSIDDIFEYYGKIK
                     DRLDEILNRDERVEQLRSKLMNIEEDLKIKASKLTKARIEVATTLEKILLDELKSLNM
                     KNVMFKVNFEKGPFTLDGVDDIEFMISFNLGEDIKPIYKVASGGEMSRFMLAFKTILA
                     DIDDIDTLVFDEIDTGISGIAAQIVGEKLSDIAKKKQIICITHLPQIAANADTHYCIE
                     KDTSNNRTFTNVSKLNESQRKNEIARLIAGNNITEKTIEHASEIIELAKKC"
     gene            33950..34816
                     /locus_tag="PC494_001011"
     CDS             33950..34816
                     /locus_tag="PC494_001011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3911532.1"
                     /translation="MNKKDTMHLIFTIVIFILLWYIVVAVSEINKNIESCSNKLDYLS
                     QEIMSTKSDISNTINEEMSKSYITKSIDLKVKKIEKKECVIDVDVQLSKLGKNGKVFF
                     MYKEDSDKWNETEMTKHGELSYACEIKINTGSEYDYKVVTSGAISESSDVQKLTKSDY
                     MPEQPIFNSGIRDNREYFIEIVENSNLFNHESEKSKNKVYDNIRLEKVDIIVNEGKKD
                     TIYKAKLAEGLDDGKTNNSNRNQVNYEVSFPKRDIDDIIYIKAKLTYNNGVEYTKDIT
                     EDITMGLQDLEK"
     gene            complement(34909..35400)
                     /locus_tag="PC494_001012"
     CDS             complement(34909..35400)
                     /locus_tag="PC494_001012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDF3911533.1"
                     /translation="MADKMAQNITLQFVEEKDLENLENVKLLFTEYSNSLNIDLCFQD
                     FNNELKTLPGKYKKPSGSLILAFVDENLAGCVALKKLEGKICELKRLYVRNQFRGLKI
                     GKILLEEIIEEAKKFGYTHMRLDTLPSMKSAQGLYEKFGFYDIEPYTYNPIEGARYME
                     LKL"
     gene            complement(35461..35901)
                     /locus_tag="PC494_001013"
     CDS             complement(35461..35901)
                     /locus_tag="PC494_001013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDF3911534.1"
                     /translation="MKLNVRIADINNWHDLVSLSVDKSQLDYIESNALSIAESKFITA
                     WVPVGIYDENSLIGFAMYGRLEDDRVWLDRFMIDSKYQGKGYGKASLDFLVNHLKNEY
                     NCDELYLSIFEDNKMAIKLYKDFGFEFNGELDYGGEKVMVLKSN"
     gene            36062..37120
                     /locus_tag="PC494_001014"
     CDS             36062..37120
                     /locus_tag="PC494_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase S55"
                     /protein_id="HDF3911535.1"
                     /translation="MNKINKNFKNIWIILGAVSIFTMVIIFNKNCNVNKETQIEAFTI
                     KNHDKKFVYPMGNIIGVKANTDGVLVLGYEEEDVDYIGGIQIGDNIVKIDNKRIKNSQ
                     DVSEILNKIKKSKVEVTFERKNKYKTEVIETKKENGKYKLGLWVRDKISGIGTMTFYD
                     PSMEKFKAIGHAIKDSDTNELLKIKQGYIYKPEQLKIVKASNEKVGKIKGDFNDSNLM
                     GNFSNNSELGISGNITENHNKEFNVANKEKQLIEVGRPQDVKIGDAVILFEDKNKNIT
                     SYDIKIESIVYDKGNYRDMVIKVVDDKLLEYTGGIVQGMSGAPIIQNNKIIGAITHVF
                     RDNPKKGYGIFIDEMIKL"
     gene            37262..38086
                     /gene="spo0A"
                     /locus_tag="PC494_001015"
     CDS             37262..38086
                     /gene="spo0A"
                     /locus_tag="PC494_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation transcription factor Spo0A"
                     /protein_id="HDF3911536.1"
                     /translation="MGGFLVEKIKIVLADDNKDFCQVLKEYLSNEDDIDILGIAKDGI
                     EALDLVKKTQPDLLILDVIMPHLDGLGVIEKLNTMDIPKMPKIIVLSAVGQDKITQSA
                     INLGADYYIVKPFDFVVFINRIRELVSNRVTQVEPKPRPVQETQMTRSDFVKNVGNIE
                     TEITNIIHEIGVPAHIKGYLYLREAIKMVIDNVELLGAVTKELYPSIAKKFNTTPSRV
                     ERAIRHAIEVAWSRGKVDTINQLFGYTVHNTKGKPTNSEFIAMIADKLRLEHSMVK"
     gene            38499..39620
                     /locus_tag="PC494_001016"
     CDS             38499..39620
                     /locus_tag="PC494_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3911537.1"
                     /translation="MRVEAPIKVDRKTKKLAKRVESGEIAVINHIDIDEVAANSLVEA
                     KIKLVINAAPSISGRYPNKGPGILTENNILIIDNVGEELFEELKEGETIEVVDGKIYR
                     KGKFLGAGEVLDKYEVSHQIKAAYENLAVELDRFIDNTIDYAKKEKGFILGEVEIPKV
                     KTNYANKHVLIVVRGQDYKEDLSTMLSYIEEVKPVLVGVDGGADALIEFGYTPDVIVG
                     DMDSVSDEALKKASEIVVHAYTDGRAPGLKRVEELGLDAVVFPAPGTSEDIAMLIAYE
                     YKAELIVAVGTHSNMIDFLEKGRKGMASTFLVRLKIGSKLIDAKGVNLLYRSKLKIKY
                     IWALIATALFPVLVVASLSPGVQQFIQLMQLKFRVLLQM"
     gene            39638..40513
                     /locus_tag="PC494_001017"
     CDS             39638..40513
                     /locus_tag="PC494_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper transporter"
                     /protein_id="HDF3911538.1"
                     /translation="MHINMKYYIVTIGAIFIALGIGMLVGFNLNNNQQLSEQQANIIN
                     DLDDKFDILKEKNDKLDSDLASVNRDYEEAVNFINKNVDKILAGSLNGKSIGIISANE
                     NDDYTKNIEDIINKSNGSIAFNIILKENITNPEKLKEMSTKLGTDVKNANDAVNYIID
                     TLKKEDASDILTYLQELDVIKFNFIGDTYLKYDSVVIAGGNDAKDSAKQFEKIEKFVV
                     SKLKSENKYLVEVQNTGVKTSYVELYSKNKVATIDNIDEGIGSISLAILLQQGNIVGN
                     FGRLDTATSLLPSIK"
     gene            40537..41229
                     /locus_tag="PC494_001018"
     CDS             40537..41229
                     /locus_tag="PC494_001018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HDF3911539.1"
                     /translation="MDSYISIIIPAYNEESRIKYTLESILDIKQINEIIVVDDGSIDN
                     TAKVVSELENEKIKFFKLDKNRGKGYALNYGIKLAMKNADIIGFLDGDLGSSAKEVEK
                     LIVPILNGEADVTIAKFPPAKRKGGLGFVKGLAKNSVFEMTGVELDATLSGQRIFKRE
                     VLEKFDEIPFGYGVEVGMTIDILKYGFKIKEVLVNMTHNETGRNLKGFIHRGKQYYHI
                     KKVLGQKKKEWR"
     gene            41237..42061
                     /locus_tag="PC494_001019"
     CDS             41237..42061
                     /locus_tag="PC494_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HDF3911540.1"
                     /translation="MKDYILYTILLLTGLFGTYAVIPLFKNLLINGNVLRPNYKKDMI
                     PVSMGIVFLPMIVINGIILAFFTTEFKDLAYIFMFMFGMISMFFAGILDDVIGNRDVS
                     GLKGHFKSLFKGSLTTGGFKALFGGFVGLIVSVAISKDIIDIIVNTLIIALSTNLMNL
                     LDLRPGRAIKAYLFIMVIIFLTLTGFVQVLPLLIVPNVLAYFNYDLKARAMMGDTGSN
                     VLGISIGMLISFGYPFNIRLGWLIFVVIMHIFTEKYSLTKIIEKNKLLNFIDKLGR"
     gene            42066..43133
                     /locus_tag="PC494_001020"
     CDS             42066..43133
                     /locus_tag="PC494_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3866 family protein"
                     /protein_id="HDF3911541.1"
                     /translation="MISKRVGIVESIVSQTETLDDIRVNINGEIQKAYNYPKISGTIN
                     IGDEVVLNTTAVELSLGTGGYHFVITNLNNIESTLTEGGHIMKLRYTPLQIKVDSVEE
                     QESIYHDKFANFKGLEGLSVVVGTLHSMLTPFAASFKRNNPNKKLVYIMTDGASLPIY
                     LSKNVDTLKEKKLIDSTITIGNAFGGDYECINIYTALITAKEILKADAVFVSMGPGIA
                     GTGTKYGFTGIEQGSILDAVKKLEGRAIAIPRISFADKRERHQGISHHSMTVFKEIVN
                     VNVDIPITIYDDEKLNFIKEQINLNGLDKKHNIIYIDNNKTKEDLDYFNLKVKSMGRN
                     YEQDEAFFKAASTAAYYLMEV"
     gene            43135..43671
                     /locus_tag="PC494_001021"
     CDS             43135..43671
                     /locus_tag="PC494_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HDF3911542.1"
                     /translation="MVLEEKTISSDRVYTGKVITLKVDTVEIPGQGYQKRELVEVGGA
                     VGIVAITDDNKVVLVKQFRKPIEKPIFEIPAGKLEKNESPKECAERELKEETGYSAKN
                     IKLIHKFFTSAGFSNEIMFVYLATGLTPGENNLDADEFLDVYEIELEEAYNMVLKNDV
                     EDAKTSIGLLLVKDMFKN"
     gene            43739..44344
                     /locus_tag="PC494_001022"
     CDS             43739..44344
                     /locus_tag="PC494_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage II sporulation protein M"
                     /protein_id="HDF3911543.1"
                     /translation="MRRTYRKNDFRELNRQIIIIGLLFMMSIVVGSYINKILPGSSNN
                     ILNNINPAVEYYNLNISIKDTVIQNLKSDAIFMGSIALLSLFVVTIPAVLVAFVLKGM
                     SIGYTINSCILALKFKSIKMILIILFKNLIIIPCAIILALISLSYFKEMVYEFKKKNR
                     KNMQFLIKRYILNIIIIIALSLGLQLILNTASIGIIKFLAK"
     gene            44356..45270
                     /locus_tag="PC494_001023"
     CDS             44356..45270
                     /locus_tag="PC494_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HDF3911544.1"
                     /translation="MDIIEGYIDYIKDKKKLSENTVASYFMDIKKYMEYINQKSIKLV
                     DIVENDIISYLIKLEKDNVSIATIARMISSIKSFHDYLFLNHICTNNPAKDIKKPKIK
                     KENINILTEEEIERLLNFPKLTTPKLIRDKAIFEVLYGTGIKVSELVEMNIEDIDLDI
                     DYIYCNSCCKNQRVIPLCDITKLYLEKYLKEARPKMAVEGEKSLFVSSLGQRFTRQGL
                     WKVIKKYSNLANIDKNINPTMLRHSFAIHLLNEGANIAVVSKILGNVNLSSLQVYLNH
                     IDKNVRREIKEKHPRNDVDVELQKAEAK"
     gene            45312..46484
                     /locus_tag="PC494_001024"
     CDS             45312..46484
                     /locus_tag="PC494_001024"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HDF3911545.1"
                     /translation="MSRVIWIVIDSVGIGALPDAEKFGDSKDVSTLGNIFKEYPDIQI
                     PNMRNLGIGNIDGIDFFESIKEPIGCFGKCKEMSQGKDTTTGHWEMTGIIVDKPFKTF
                     EHGFSKEIIEEFEKKTGRKVVGNKPASGTVIIDEYGEHQIKTGDVIVYTSADSVFQIA
                     ANEEVIPLEELYNMCKIAREIMMGDNAVARVIARPFIGKKKGEFVRTSNRRDYSLDPF
                     EPTVLDNIKESGLDVLAVGKIEDIFNGKGITDAIHTKSNMDGVDETLNYMKQDNKGLI
                     YSNLVDFDSKYGHRRDPEGYKKALEEFDSRLPEIMANMREDDILIINADHGNDPTYKG
                     TDHTREYIPVMIYGNKIKKGFNLGVKDTFADIGATVADILNVKLPKHGSSFKEDLF"
     gene            46531..47343
                     /locus_tag="PC494_001025"
     CDS             46531..47343
                     /locus_tag="PC494_001025"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HDF3911546.1"
                     /translation="MFEKIAQSSKFINSKSDIKPKIGLILGSGLGDLANDIEDPVAIK
                     YSEIPNFPVSTVAGHAGQLVIGKLEGKEVIAMQGRFHYYEGYSQKEATFPVRVMKELG
                     VEILIVTNAAGGVNKEFKAGDLMLIRDHINFSGSNPLVGKNDDRFGARFPDMSDAYSS
                     KYVDVVKNCAKECNIDVKEGVYMFFSGPNYETPAEVRMAQILGADAVGMSTVPEVIVA
                     SHSNIGVIGISCITNMAAGILNQPLSHEEVIETTQKVKSEFMNLVKTTVKNL"
     gene            47547..48872
                     /locus_tag="PC494_001026"
     CDS             47547..48872
                     /locus_tag="PC494_001026"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HDF3911547.1"
                     /translation="MRMYDIIKKKRDNLELSKKEINYFIENYSKGDIPDYQASALLMS
                     IYLNKMNKQETVHLTEAMMNSGDMINLSEIDGIKVDKHSTGGVGDKTTIALIPLVASC
                     GAPVAKMSGRGLGHTGGTIDKLESIPGFSTEMEISKFIDSVNKSKIAVCGQSAKVAIA
                     DKKIYALRDVTATVDNISLISSSVMSKKLASGADAIVLDVKTGDGAFMKTLEESFELA
                     KSMVDIGTGMNRDTIGIVTDMDEPLGFAVGNSLEVIEAIETLKGNGPKDLVELCEVLG
                     AYMLVLSKVAHDFEDGVEKIRESIKSGTAIQKLKEFIENQGGNKDVVDDYSLFKKSKY
                     KYPVKSTKSGYISKIKAEDVGVSAMILGAGRETKDDILDLSAGIILEKKVGDYVNEGE
                     VLAYMYYNDEQKLSLAKGRFIDSYSIVDSKIEKNKLIYGIVTKEEIKKF"
     gene            49085..50164
                     /gene="mltG"
                     /locus_tag="PC494_001027"
     CDS             49085..50164
                     /gene="mltG"
                     /locus_tag="PC494_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HDF3911548.1"
                     /translation="MNFKENRLKIAVLIIVILIILAGIFVFIQIGPYDKNNKKDVIID
                     VPSGASVGKISDILYENKLIKNELLFKLLVKVSNKAPSIKSGTYLLNQSYSNNDIISL
                     LVSGKIYQDGIKVTIPEGATSKEIIAMLVSKNLGDKATFENLIKKPQEFYDKFPYLKE
                     DGITSLEGFLYPETYYFNSKKQSEEDILSEMLKVFDSKYTDKFKKKQKELNMTLQEVM
                     EMASIIEKEAVLDKDRPIIASVFYNRLKVGMPLQSDATIQYIFEERKKIVTYDDLKID
                     SPYNSYKNKGLPPTPISNPGIKSIEAALYPEKTDYLYFVAKIDGGNNYSTNYQDHLKY
                     VKEYKEARDKQSKDTKATNKENTKK"
     gene            50336..51010
                     /locus_tag="PC494_001028"
     CDS             50336..51010
                     /locus_tag="PC494_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HDF3911549.1"
                     /translation="MSNIVNDLVEDYIRVTLKEKEGFLKDLEIYAEENSVPIIHKEVS
                     DLLKVLLKVQKPKRILEVGCAIGYSSIFFATIIGKDADIITVERNEKMIEKAKENIKL
                     AGFDNNITILEGDAEEKLSQVQGEFDLIFIDAAKGQYKLFFDLVIDKLKDGGLLVSDN
                     ILYKGMVAHDDFVVRRKKTIVKRMRNYLDYICNCDYLSTSLVPIGDGVALSYKESKRG
                     DVDGIK"
     gene            50997..52244
                     /locus_tag="PC494_001029"
     CDS             50997..52244
                     /locus_tag="PC494_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HDF3911550.1"
                     /translation="MELNKVELLAPAGDLERLKIAITYGADAVYIGGEIFGMRSAAKN
                     FSKEDMAEGVAFAHERGKKVFVTVNIIPHNEDFLQLEDYLLELEEIGIDAVIIADPGV
                     LSVIKKVIPNMEIHLSTQANTTNYLSANFWYEHGIKRVVVARELSFDEISEIRAKTPL
                     DMDIEAFMHGAMCISYSGRCLISNYMTGRDANKGSCAQSCRWQYHLVEEKRPGEYFPI
                     YEDERGTFFFNSKDLCMIEYIPELIKSGITSLKIEGRMKTAYYVATVVRAYRMAIDEF
                     YRDPENWKFNPMWMEELKKGSHRHFTSGFYLNKPTTEDQNYQSASYVRNYDFIGIVRE
                     TEDEDGLIVVEQRNKMCVGDEIEVMGPYKETMFTKIEEMYNEEGEAIESAPHPRQIVK
                     LKLSVKVGKDYMLRKVIEEKVEE"
     gene            52316..53980
                     /locus_tag="PC494_001030"
     CDS             52316..53980
                     /locus_tag="PC494_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2"
                     /protein_id="HDF3911551.1"
                     /translation="MSKKKTPFLKKVGKRSWCIFTIILIIYSVLIYRLVDIQVLKGDK
                     YKQSVESQSVEKVELNSGRGIIYDRNNKKLTDTSKSQVLIVEKEKLNNNYKILELIKK
                     ATKMNDLDIYKAVQEQLTRPIIQIQTKNIDKSMKKELEKNGIMVEEKTMRYAKDGLLS
                     HTIGYIKEDDKSGQSGIEKSMDSVLRNSNEKYISAFKAGDAGNEKSLNILKGSVKTVD
                     NKDKDRHLKTTIDYNIQKKLEQILNKEENPTAAIISEASTGEILAMCSRPNFDQNDIS
                     KSLKGKNGEFENRVIKATYPPGSVFKMVVLFSALENGVIDENYTYNCTGKTKVGNTNE
                     ILRCNKRDGHGFQNLRQAFSNSCNPAFLDIAMKLGKEKILKSAEKLHLFEKVDIGLDE
                     EKIREAPKNISIRNLAIGQENIEFTPLQINQMTQIIANNGTFKPLYLYKSLVDNNMNT
                     IKTYKSSKKEELISPYVCTQVKEYMKSVSRIGTAKDLKDIEGGCGVKTGTAQSSLNKK
                     AIDHGWITGFYPEERPKYVITVLVEGTQKGNKSATPIFKEICESIK"
     gene            complement(54077..54361)
                     /locus_tag="PC494_001031"
     CDS             complement(54077..54361)
                     /locus_tag="PC494_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012063608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HDF3911552.1"
                     /translation="MCNEISLLDILGTEANYVLDEVELKVQVGKLYEQLNKILTPRER
                     EIVQLRYGLTPYGYKTQREIAQKLDISRSYVSRIEKKALKKLEKELVQES"
     gene            complement(54384..55901)
                     /locus_tag="PC494_001032"
     CDS             complement(54384..55901)
                     /locus_tag="PC494_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HDF3911553.1"
                     /translation="MSVAIYLRKSRADEEAEKQGEFETLSRHKSTLLKLAKEQNLDVI
                     EIKEELVSGESIIHRPKMLELLKEVEENKYDAVLVMDLDRLGRGDMKDQGIILETFKE
                     SKTKIITPRKTYDLTDEFDEEYSEFEAFMARKELKLISRRMQRGRIKSVEEGNFIGTS
                     APFGYDAVTTGRKERILVPNKDADVVRTIFDLYINEDMGCSKISKYLNNLGIKTATGA
                     NWYNSAITNIIKNKVYCGYIQWQKKDYKKSKNPNKIKTVKLRPKDEWIEAKGKHEPLI
                     SEITWKKAQNILKKNGHVSYGNQIKNPLAGIVICKNCGRPLVYRPYADHDYIICYHPG
                     CNKSSRFEFIEAAILKSLEDTVKKYQLKASDIDLDKNNKDSNIEFQKRVLKGLETELK
                     ELGKQKNKLYDLLERGIYDEDTFIERSNNISSRTEEIKDSIKTVKNRLSTVKKDNSKI
                     IEDIKTVLSLYHDSDSLGKNKLLKSVIDKAVYYKSKEQKLDSFELMVHLKLHEDQ"
     gene            complement(56026..56847)
                     /locus_tag="PC494_001033"
     CDS             complement(56026..56847)
                     /locus_tag="PC494_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HDF3911554.1"
                     /translation="MIISKKITAILVSFLIMISMVGCAPKESATEVAKKYLDSIKIKD
                     YEVAYNLLSKDSKESVSLEKFEEYQDTLFKLQTLKDYKLGEENKVEKYKYSNKEYTNL
                     VKIKETDTIKYITENKEDTANFDRYFIIEDNEYKLLWHKDFKRALSSNYVKIARSETE
                     KDEDKDYNKAAIDIKKAIEIDDKNPLAYYTQSYIYIELQRYDEALKSIDKYLEYLDKN
                     NEAYKIDASDAYNLRGVIFMSKSEFNKARESYNKALELNPDNEYAKTNLNDIKGL"
     gene            57038..58465
                     /locus_tag="PC494_001034"
     CDS             57038..58465
                     /locus_tag="PC494_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp26"
                     /protein_id="HDF3911555.1"
                     /translation="MKIKKLLTIGLSLSIFIASCPISANALDKIESIKGADKYETAGI
                     IADKQNYTTAILINADSTMSDGLSASGLAGAINAPILLTKKNNIPNATLKRLEKAKKV
                     YIIGGENSIDKYTETVLKGKGIEIKRLQGSDRIKTSYNVAKEINSINKVNKVILTNAF
                     KGEPDAMSVAPVAVRDKAAIVLTDGKSVPFNTTGVESYVIGGTSSMNDKIVKDTNSTR
                     LGGTDRYDTNKKIINKFYSGVKEFYIASGTDLVYALVGSTAAKNNAIVLVDNDSNKSV
                     LKSTTKLTAIGNLSDSILQQCLNVTKNIGDSNTGREYTVEDAANAVKKLLGVKKFYYK
                     PNYSEDEDLIFLLDKNFDFSGKEYYVFAYIKQGAEGDVRYCVAKNDMSKVYTYDVNGN
                     MKVCNPDDYKNKGSITEEQAKQIALKECAKRHKVSINNLVVDMIDFRDDIYSGNVYAV
                     KINSKNSNGTFGWFFIDIETGKVYN"
     repeat_region   59421..59779
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=59421..59449
                     /rpt_unit_seq="gttttatattaactaagtggtatgtaaag"
     gene            complement(60066..60290)
                     /locus_tag="PC494_001035"
     CDS             complement(60066..60290)
                     /locus_tag="PC494_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF3911556.1"
                     /translation="MDVNQRIKYIRENMNSSQKELLEKTNINTSVMNRIESGERPTRD
                     DGLIIFAKIFGLYTDYILGLSDTEKLNIGN"
     gene            61001..61156
                     /locus_tag="PC494_001036"
     CDS             61001..61156
                     /locus_tag="PC494_001036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="regulator"
                     /protein_id="HDF3911557.1"
                     /translation="MALDVKIEVKIIKDVVILNITHWKKETSLLTVKIARSQGDLSYV
                     KYFANES"
     gene            61402..61653
                     /locus_tag="PC494_001037"
     CDS             61402..61653
                     /locus_tag="PC494_001037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3911558.1"
                     /translation="MSSYFITRGDVMKILQQFKPYKYDKEKNIEYDEKIIANQNTEVY
                     IVYPRISDEENRRRWEEFNEVAKEVAINIAMKKVETVES"
     gene            complement(62863..63246)
                     /locus_tag="PC494_001038"
     CDS             complement(62863..63246)
                     /locus_tag="PC494_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3911559.1"
                     /translation="MRKKFFIGILIVLIISVIAILNIKNDKNVFIGESENWKAKFVTT
                     EGHSKLEIKYKNSKDVVEQKFNYSYQFIDGEDAVVVVKNEILEAGQEKAIKIQRPGLY
                     SNRESSYKLIISWNGNEETINLKKK"
     gene            63373..63717
                     /locus_tag="PC494_001039"
     CDS             63373..63717
                     /locus_tag="PC494_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3911560.1"
                     /translation="MNYRLKKSVTTILSLLIMTILLPTNASASKVEDSSMKVMYSEKQ
                     VTDMDKLYDMAKNGITDVKSSNEKGIIKNARTGESIYVDSISTTQLLEVKQSKNLTSK
                     IYSKTVFLILIQ"
     gene            63900..64115
                     /locus_tag="PC494_001040"
     CDS             63900..64115
                     /locus_tag="PC494_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3911561.1"
                     /translation="MHINQTGFISNELGIKQQQKKEPTSNSFSYNAPSSWKPVGRDSV
                     QYNCGFELIATLVRGGSSWAFNFIVQP"
BASE COUNT        25734 a         6678 c        11514 g        20333 t
ORIGIN      
        1 tcgtttaatg tatacaataa tatatctata acaaaataat aaaagataga gttttattta
       61 gacatttatt acaaatcaaa atttattaca tattatttat aaaaaaatct aaggaggaaa
      121 taataatgaa aatattagta ttaaactgtg ggagttcttc attaaaatat caattaatag
      181 atatgaataa tgaagaagtt ttatgtatag gattggttga aagaatagga atagaaggtt
      241 ctatattaaa acatgaaaaa gcaggtagag atgataaata cgttgttgaa caaccaatga
      301 aggaccacaa agatgcaata gcattagttt tagaagctgt tgctcatcca gaatttggtg
      361 cagttaaaga aatgaaagaa atagatgcag taggacatag agttgtacat gctggagaaa
      421 aatttgcaac ttcagtagta ataactccag aagtagaaga agctttaaaa gaatgtatag
      481 atttagctcc acttcataat ccagcaaaca taatgggaat agatgcttgt aaagctatac
      541 ttccagatgt accaatggta ggtgtatttg atactgcttt ccatcaaaca atgcctaaat
      601 cttcatactt atatggttta cctcatgagc tatatactaa atatggggta agaagatatg
      661 gattccacgg aacttctcat aattatgtat ctcagagagc agcagagata ttaggaaaag
      721 atataaaaga tttaaaaata gtaacttgtc acttaggaaa tggtgcttct atagctgctg
      781 ttgatggtgg aaaatgtgta gatacatcta tgggattcac tccattagaa ggattaataa
      841 tgggaactag atgtggagat atagacccag ctatattacc attcttaatg agaaaagaag
      901 gtttagatgc tgatggattg gataaattaa tgaataaaga atctggagta tatggaatga
      961 ctggaatttc tagtgacttc agagatatag aagatgcagc taaaaatgga gacgaaagag
     1021 ctcaagctac attagaagcg tatgttaaaa aagtacaaaa atatataggc gcttatgctg
     1081 ctgaaatgaa tggattggat gttgtagtat ttactgcagg cgttggtgaa aatggaaagg
     1141 ctataagagc agatattgct tctaacatgg agtttttagg aatgaaatta gataaagaag
     1201 ctaatgatgt tagaggaaaa gaaacagtaa tatctactgc tgattctaaa gtaaaaatgc
     1261 ttttaatacc aactaatgaa gaattaatga tagctagaga tacattaaga ttggtaaaat
     1321 aattaaatta aacctatgcc tatcaagtaa aaatacttga caaacaaatg ctagatttgt
     1381 ataataaatt tggtgatatg ttgaggtgaa cttaatgaaa gttagcatag aaaaaataaa
     1441 tagaaaagaa actgacaaaa tagacttgaa tttttgtgaa aaaattgata ctattagtta
     1501 ttgtgatgag atttacaaat tagtatcacc tgtaaattta aaagggaaag tgtcaaagac
     1561 taataaaggt ttgtatctag atatagatgt caattttaca attgttgaca attgttcaag
     1621 atgtcttaaa gaagtagaaa taccactaga gtattctata caaggttttt tagtaaaaga
     1681 agaagattat gatgaagatg agtttgagga atttgatcct tttatattcg atggtgaaga
     1741 aatcgacctt attgatataa tagaacagac attagatttt aatgtacctc ataaagttct
     1801 ttgtagtgaa aactgtaaag gtctttgtca agtatgcggg gcaaacttaa atgaagaaga
     1861 gtgttcttgc agtgaaatta caaacgatga ggaatacata gatcctcgtt ttgctaaatt
     1921 aaaagattta tttaattaaa ttttgactaa ggaggtggcg taaatggcag taccaaagcg
     1981 taaaacgtct aaatcaaaca caaaaatgag aagagcagct aactcaaaga tggaagcaac
     2041 aggatttgta agttgcccac aatgtcatga gccaaaatta ccacatagag tgtgtccaga
     2101 ctgtggatat tataaaggta aagaagttgt gtctaagtaa tagcttctaa aaagcatgta
     2161 gagtatactc tacatgtttt ttttgtacat ataaaaaaat aagatgattt actagagaaa
     2221 ataagtggat tttatgcata ttaaaaaata gaaaaataat aatataagta ttgaaaattt
     2281 ttgtgtgtta ctatatacta ctattagtag ctggtactaa ttacagctat aaaatttgga
     2341 gggaacatga aaaagaaaag taaagcccaa agacaaaaag agcttataga tatgctaaag
     2401 acagatcctt tttatactga tgaagaatta tcaagtctgt ttgatgtaag tatacagacc
     2461 ataagattag atagaatgag tctaaacata ccagagctaa gagaaagagt caaatcaata
     2521 gcagaaactc agagttcaaa agtaaagact ttaggagtaa aggaaattac aggagaaatc
     2581 attgatttat ctgtagggcg attaggtata tctatgttag aagttacaca ggacatgatt
     2641 tactctaaga ctaatacttt aaaagatacg tatatttttt ctctagcaga ttcattggca
     2701 atggctataa tagatgcacc taaggttatt atgagagttg caaatgtaaa aagttttaag
     2761 ttgatagaac aacaagatag acttatagca aaagcagaag tgtatagaaa tatagataaa
     2821 aagcattatg taaaagttgt tatcaacaat aaagcccaag agcaaatatt tagaggaaag
     2881 tttatctttg aagaattaga ttaggaggga aattatgaaa atagtaattg atggaatggg
     2941 tggagataat gcacctaaat ctaatgtaga aggcgcagta aatgctataa aagaatatca
     3001 ggttgattta ataatcacag gagataaaga tttacttgaa aaggaatttt caaattatga
     3061 atttgataga aataaattag agatagttca tactactgag attatagaaa acgaagataa
     3121 accagtaaag gctataagaa gtaaaaaaga ttcatctatg gtagtagcat taaatcttgt
     3181 aaaagaagga aaggcagatg ctataatatc agctggaaat acaggagcct tacttgctgg
     3241 tggattattt gttgttggta gaataaaagg aatcgataga ccttgcttat gttcagcaat
     3301 accaaatgta aagcgaggaa tgacacttat agcagactgt ggcgcaaatg cagattgtaa
     3361 acctaagaat ctagttgaat ttgcagctat gagtaatatt tattcaagaa aagttttagg
     3421 tcttgaaaat cctaaggtag cattagcaaa tgttggacta gaagaaggca aaggcaatga
     3481 tttagtcaaa aggtcatatg aagaaattaa aaaattagat ttaaatttta tagggaatgt
     3541 agaagctaga gaagttataa atgcatacac agatataatc atatgtgatg gatttacagg
     3601 taatatatta cttaaatctg ctgaaggtgt agcactttca gttatgagtc ttataaagga
     3661 aacttttatg gccagtacaa aaagtaaaat aggagcatta cttataaagg atgatttaag
     3721 aaaattaaaa agttttatag attattctga gtatggggga gctccacttt taggtctaaa
     3781 tggaggagtt ataaaagctc atggtagttc tgatgctaaa gctataaaaa atgctataaa
     3841 tcaaggaata aaattttcaa agggaaaagt cgttgaagat attaaccaat ttataagcaa
     3901 atacaatgaa gaaaataaaa ataacgaaga tgaataaact cgttttggag gtttaatata
     3961 taatgaatac aaaggctgga atattaggag taggaagtta tctacctgag caatcatatg
     4021 ataattttca cttcgaaaaa ataatggata catcagatga gtggataagt actagaactg
     4081 gtattaagga aagaagattt gccaaagaat ctgaagcaac ttctgactta gcatctaaag
     4141 ctgccttaaa agctatagaa tgtgcaaagt taaacgtaga ggatatagag ctgattatat
     4201 tagctacaat tactcctgat atgtctttgc cttcaactgc atgtatagta caagatgcaa
     4261 taggagcagt gaatgctact gcatttgata tatcagcagc ttgttctgga tttgtatatg
     4321 gagtaactat tgcaaagcaa tttgtggaaa caggttgcta taaaaatgtg cttgtaatag
     4381 gagcagaaac ttgttctaag tttttaaatt atgatgatag aacaacagca gtattgtttg
     4441 gagatggagc tggagcagct gttattggcc ctgtaaatga gggtggaata ctgtctacac
     4501 atatgggctc tgatggtaaa ggaaaagatt gtttaaaagt acctgctgga ggttcaagac
     4561 ttaaggcaag taaagagact gtagaagcta atctacatac aatagaaatg gcaggtagtg
     4621 atgtgtttaa atttgcagtt agaaagatgg cagaaacttc tttaagagct cttgaaaaag
     4681 caaatctaaa tacaactgat atagactact tagtgccaca tcaagctaat ataagaatca
     4741 tacaagcttc ttctaagaga ttagagcttg atatgaaaaa agtttatgta aatatagaca
     4801 aatatggaaa tatgtctgct gcatctatac cagtagcatt agatgaagct tatagagaag
     4861 gtaaaattaa aaagggtgat aatgtagttt tagttggctt tggtggaggt ctaacttggg
     4921 gggcttcagt tgtcaagtgg actttatagt ataaaatatc taaaatgatt taattaacaa
     4981 aattaaactt atacacaaaa taaagttgat taataataaa aagtttactt ttatgatttc
     5041 aagtgaagga gaattgtatg aataaaattt gcaaaatatt aaatataaaa tacccagtta
     5101 tccaaggggg aatggcatgg gtagctactg catcattagc aagtgctgta tctaatgcag
     5161 gaggacttgg cataatagca gcaggaaatg caccaaaaga agctataaag aaagaaattg
     5221 ttgagtgtaa aaaattaaca gataaacctt ttggagtaaa tgtaatgctt atgtcgccat
     5281 ttgttgatga tataattgat ttgattatag aagaaaaagt tcaagttatt actactggtg
     5341 ctggaaatcc tgcaaagtat atggatagat taaaggaagc tggaacaaag gttattcctg
     5401 tagtacctac aatagctttg gcacaaagaa tggaaaagct aggagctaca gcagtaatag
     5461 cagaaggtac tgaaggtgga ggacatatag gagaacttac tactatggtc ttagttccac
     5521 aagttgctga tgctgtaaac atacctgtaa tagctgctgg aggaattgta gatggtagag
     5581 gaattgcagc atcatttgca ttaggtgcca gtgcagttca agtaggaact agatttattt
     5641 gcagtgaaga gtgttctgtc cattcaaact ataaaaactt agtactaaaa gcaaaagata
     5701 gagatgcaat tgtaacagga agaagtactg gtcatccagt aagaacatta aaaaataaac
     5761 tatcaaaaga atttttaaag atggaacaaa atggagctac tcctgaagaa ctggataaaa
     5821 aaggtacagg agctttaaga tttgcaacag tagatggaga catagaaaaa ggttcattta
     5881 tggcaggtca aagtgctgct atggtaaaag aaataacacc ttgtaaggaa attatagagg
     5941 ctatggtaaa tcaagcaaga gagattatgc cagcaataga actgtaaatc aggaggagca
     6001 agatgggaaa agttgcacta gtattccctg gtcaaggagc tcaatatgta ggtatggcca
     6061 aggatttata tgaaaataat actgttgcta aaagtgtaat agatgaggct agtgatgcct
     6121 taaatatgga tttaaaaaac cttatgttta atggaaatga agaagaactt tctaaaactg
     6181 aaaacactca acctgctatg gttacacata gtgtagcagt attaaaagcg gtacaagctc
     6241 aaatagattt aaaatataat gcatgcttag gattatcctt aggagagtat agtgcattgg
     6301 ttgcagcaga tgcaattgac tttaaagatg ctgtatgttt agttaaaaaa agaggtaagt
     6361 ttatgcagga aacagttcca gcaggtgttg gagctatggc agcaatttta ggtttagata
     6421 gaaatgtact tgaaaatgtg gttaaagata tacaaggagg tattgtagaa gtagcaaatt
     6481 acaattctcc tggacaaata gttatatctg gtgaaaatga aaagatagaa gaagcaatgg
     6541 taaaatgcaa agaagcagga gcaaaaaggg cagttaaatt aaatgtaagt ggaccttttc
     6601 actcatcaat gttaaaagaa gctggtgtaa aattggccag tgaattagaa aaagttaaca
     6661 taactaaacc taaagttgat gtggtggcaa atgtaaatgc agattactat aaaaacgaag
     6721 gtaaagacct gcttataaaa caagtaagtt catctgttct ttgggaagat tctatagaaa
     6781 gacttttaaa tgatggatat gatactttta tagaaatggg acctggaaaa actttaaaag
     6841 catttattaa gaagatagct tccaataaaa aagcaaatgt caatatttat aatatagatg
     6901 gtatagattc tcttaatgaa tttgtacaaa attatagaaa tggagagata taatgataaa
     6961 tcttacagga caagtagcag ttgttactgg tggctctagg ggtataggaa aagaaatagc
     7021 aaaaaaacta gcatcttttg gagctgatgt agtaatcaat tatacttcta aagaagatga
     7081 agcactaaaa actaaaaatg aaatagaaag tatgggggta aagtgtacct ctataaaatg
     7141 tgatgtgtct aaatttgatg aagtgaatca aatgatagat tctgttgtaa gcgaatttgg
     7201 aaaaattgat atattggtta ataatgcagg cataactaaa gatggtctgc ttatgagaat
     7261 gaaagaagaa gattttgata gagttataga tataaactta aaaggtgtct ttaattgtac
     7321 aaaagcagtt actaaaccta tgatgaaaaa gaagtatgga agaataataa atatgacttc
     7381 agtagttgga attatgggta atgcagggca aactaattat tgtgcatcaa aagcaggtgt
     7441 aattggattt acaaaagctt ctgcaagaga gttagcgtca agaaacataa atataaatgc
     7501 agtagcacct ggatttatag aaacagatat gactaaagta ctaagtgatg atgtaaaaga
     7561 atcaacacta gcaaacatac caaagaaatc ttatggtaaa ccagaagatg tagccaatgc
     7621 cgtagcattt ttagttagtg acatgtcaag ttatataaca ggacaagtaa taaatgtaga
     7681 tggtggaatg gtaatgcaat aataatttaa aaagtagaga aatctattaa aataaaaaat
     7741 tttaggaggt acacaatgtt taataaagtt gtagaaataa taatagagca attaggagta
     7801 gaagataaag aaataactat ggagacatca ttaatgaagg atttagaagc agattcatta
     7861 gatgcagtag aaataataat ggcacttgaa gatgaatttg gtatagaaat accagataca
     7921 gaagcagaaa acttcaaatc tataggagat atagttaagt atatagaagc taataaatag
     7981 tcgagcttta aaaaagtgga ggtatccgat gaataaaaga gtagtaataa caggacttgg
     8041 atgtgttacg ccgttgggaa caggaaaaga agagttctgg agtaatataa aatctggagt
     8101 atctggtata gataaaataa ctaattttga tgctagcaca tatcaaactc agatagcagg
     8161 agaagttaag aattttcatc cagaagaata tataagtaaa aaggaattga agagattaga
     8221 taaatttgct caatttgcaa tagtatctgc taaattagca gttgaagatg caaatcttga
     8281 tttagataaa gttgatagag aacgttttgg tgttataata ggttctggaa taggtggagt
     8341 tgaagctata gaaactcaac ataaaattct tttggaaaaa ggaaataaaa gagtaagttc
     8401 actttttgta cctatgatga taggaaatat ggcagctggt caagtttcaa tatttttagg
     8461 agcaaaagga cctaacacta atgtatgtac agcttgtgca tcaggaactc attcaatagg
     8521 tgatgctttt aaggtaattc aaagaggtga tgcagacatt atggtagcag ggggttctga
     8581 agctgctgta acaggtcttg cttttgctgg attctgtaac atgaaggcta tgtcaactag
     8641 aaatgatgac cctaaaactg catcaagacc atttgataaa gacagagatg gttttgtaat
     8701 gggagaagga gcaggtattg ttatcttaga agacttagaa catgctttag caagaggtgc
     8761 taaaatatat gcagaagtag ttggatatgg tttaactgct gatgcatacc atatgacaac
     8821 tccagctgaa aatggagagg gagcagctag gtctatgaat atggctttga aagatggaaa
     8881 tgttccatta gaagaagtag attatataaa tgctcatgga acttcaactt attacaatga
     8941 tttatatgaa actatggcta taaaaactgt atttggagaa aaggcatatg acttatgtgt
     9001 gtcatcaaca aaatctatga ctggtcactt attaggagca tcaggtgcta tagaggctgt
     9061 tgtttgtgct atgagtatag aagatagttt tgtgcctcca actataaaca tacaagaagt
     9121 tggtgaagat ttggatttag attatgttcc aaatcaaggt aaagaaaaaa atattagata
     9181 tgcactatca aattctttag gatttggtgg gcataatgct acaatagtac taaaaaaata
     9241 tgtataaata aatattaaat ataaaactaa aaaacaagca cttgttttaa ctgtataaat
     9301 ttatattagc ttaaatttaa agtctcctaa attattttag gagacttttt tattaagatt
     9361 taagtctagg atatgttgta aatcattttg atatattgta ttattaatta ttaagaggtt
     9421 atttatatat gcaagttttc attctacaat atacaaaagg aggactaaaa ttttgaattt
     9481 tagactacca aagaaaaggt tacccaaaaa gataattttt atatgtataa tacttattag
     9541 tattattttg tttataaagt atgaccaaaa tggattgaaa gaaagagaaa ttataaataa
     9601 gggaaaatat atgtctgaaa gccttgtggc agataaggag tatgatgaag caaaaaaagt
     9661 ggttaagact tcttttgaat ctattccaga aaaaaaatac aataaagtat ataatgaagt
     9721 ttgggatatg ttaaagacta tttcatatgt tccagatgga acgaagatag tcattgattc
     9781 tttagaaaag atgagagaat cagatgtgaa attatctgat gaatgtagat ttaatataga
     9841 aaaaagatta gcatcagtgt atataatgga taataattat tctaaggcag tagatttaac
     9901 tgtaaagtct ataaagttgg ctgagaaatt ggggaataat tatgaaaaag caagactaga
     9961 tgttgatttg gcgagcatat ttttaaagat aggtggctat gaaacaggag agaaattaat
    10021 aaaggattct tttaaaatag atattgatga aggtgaaaaa aatggaatgg ttagattata
    10081 tgctattata aatctagcag aaatatatgt agaagaggga gaatatgata aagctattga
    10141 aataagtagc aggataaaag attataaaaa gtttgtaaat acggataatt acaatgattt
    10201 tgatataatg gcctctataa tgcagtcaaa tgcgtatgtg ggcaaaaata atatacaaaa
    10261 ggcaaagact ttgttagaaa aagctgatta tcttataaaa tcagatagaa cagtttatat
    10321 attagataaa gatatgtact attatatggc aatgggaaac ttagaatata aaagcgaaaa
    10381 ttataattct gcaatagata attataaaaa aagtttagag atatctacca aaagaaagtt
    10441 aacccaggag aaaataaaaa atttaaataa gatattaaat atatatgaaa aacaaggaaa
    10501 tatagaatct ttaaatgagt atcaaaagat gttaataaat gaatataaag agaacaaaag
    10561 tataagagat tcagagacta gtttctatat aattgataaa gtatcaaacg aaagtaagct
    10621 atttgaaaaa actaaaaaag aaataaaata ttataaaata ttatttaccg taattttaat
    10681 tgctatatta gggtctactt ttttatacaa ccgattgaag tattttaaag cacaaaattt
    10741 acatgatggt cttacaaatg tttataatag aaaaagtttt gatattatgt atgaaaagta
    10801 cagagagaaa gatgataatt ttgcacttgt gatgatagat attgataatt tcaagctcat
    10861 aaatgataat tatggacata aatttggtga cactgttata aagggaataa caaataccat
    10921 ttgtgttatg ttagaacaag atgataaagt ctttaggtac ggaggagaag aattttctgt
    10981 attaataaga aataaatctg gtgaggaagt agcagatata attgacagta taagggttgc
    11041 aattgcaaat aaaaagtgga atgatgatgt gactgtgact ataagtgcag gtgtagctca
    11101 tatttcagat agcaaagatg tactagaaga agctgataaa aatttatata aagcaaaaca
    11161 acttggtaga aataaagtag tatataagta attatatact atataaataa gaggtataaa
    11221 tatgaaacaa tcaatagcta tagtaactga taaaataact aaactatcat ctttcttaga
    11281 agaaaatata cgtttggttt taggtaatta tattgatata aaccactatt atctggaagt
    11341 tttaaaagag aatgataaaa tacaaggtga ttttgtacta gtaatgaatg atgatagatt
    11401 aaacagtatg agaaagcatt tagtacaaga tagtaagatt atagtgataa ggagaacact
    11461 taaagaaaat gaaatatatg gattattttc aataccaaat ggaactgaag tattggttgt
    11521 aaatgataca aaagaaacta ccttagaaac gataagctta ttttacaaaa taggagtaaa
    11581 aaatttaaag tttactccat atattgaagg aaaaatttat aaaaatatag acatagctat
    11641 aacgcctgga gtaaagggaa aagtaccaag ttatataaat aaagtaatcg accttggaaa
    11701 tagatatatt gatatatcta cctttataga aataataaat ggtcttagaa tagatgttaa
    11761 agaaatacgt aaaaatttaa tggcatattc tgagagttta ataagtttag ataatggagt
    11821 taaagataat tataggcaac tgtttttaaa aatagaagaa caagatgtta tattgaatct
    11881 atcaaaagat ggaataatat ttacttcagc agatggtata ataaacacat ttaataaaga
    11941 agctttaaaa attttaggta taaatgaaaa tccacaaggc aaaaacatag aagatatcat
    12001 ttctgaagat ttaaatattt tacttgaaga caaagaaata attgatgaag tggtatttac
    12061 aaataaaaaa tatataaatg taaataaaaa aagtattttt tctatgggga ataaagctgg
    12121 gatatattat aacttacaag aaataacgta tataaaaaaa ttagaacaaa atcttactaa
    12181 taaattaaga gaacaaggtc agatagcaag atatgcattt aaagatataa aaactaaaaa
    12241 taaaaatatg gtaaagtgtg tagaattggc taaaaaaata tctaaatcag acctttctgt
    12301 attaataata ggagaaagtg gtactggtaa agaattatta tcacaatcaa ttcataatgc
    12361 ttccaataga agcaatcaac cgtttatagc agttaattgt gcagcagttc cagatagtct
    12421 attagaaagt caactgtttg gatatgaaaa aggctctttt acaggagctt taagagaagg
    12481 aaaaaagggt ctatttgaac ttgctaataa tggaactata tttctggatg aaattggaga
    12541 tatgcctcca ttgctacaga caaagttact aagggtatta caagaaaagc aggttatgcc
    12601 tataggttcc cataatgtta taaacataga tgttagggtc atagcagcaa caaacaaaaa
    12661 cttactaaag atgattagag aaggaaaatt tagagaggac ctgtattata gactaaatgt
    12721 attgccaata gatgtaccat cattgaggaa tagaaaagaa gatataataa cacttatgaa
    12781 tttctttttg aaaaacaata taagactttc gccagaagtt ataactattt tagaaaaata
    12841 taattggcca ggaaatataa gagagttaca aaatgttgct tcttatgtaa gtctaatgtg
    12901 tgatagtatg gtttttagag atgacttacc accatatata agggtagaat gtgctaacaa
    12961 ttatgaagat ggatttggtt atacaagaaa agaatttgag gaaatactga ggattctata
    13021 tgaaagaaga gagtcatcct ctggaattgg aagagggttt ataatcgaaa agcttataca
    13081 ggaaggtatt gagatttctg aaagcaaagt tagaaaggtg ctatcttatt taagtgaatg
    13141 tggatacata tcatctaaat ctggtagagg aggaagtcaa ataacctcag aggggataaa
    13201 actttataat aatataaatt aagctaagta ttttatattg aaatcacata ttttgaattt
    13261 agatatttaa ataataataa acttttatat ttatagagat taatttatat tatgtcagaa
    13321 agaatattgt aatttataat taaatattaa taggttttta aaataggatt agataggtaa
    13381 taggttaagt tagaataacc cattacctat ttttatttgt aagaaaagtg tacatagaat
    13441 tagaagtaaa aaatacaact aataaaacta ttgaaaatac tagataaata ataaataaaa
    13501 ataattatag attttggcat acatattgct aattatagag ataagacgac aaaataattg
    13561 ggaggtttaa tgatgaaata caaaacaaca gggacttgtg ctacagaaat tgaatttgaa
    13621 gtaaaagaaa ataaagttac aaatgtaaac tttataggtg gatgtgatgg aaatttaaaa
    13681 gggctaaaag tattagttga aggcatgaat atagaagatg taatacaaaa gttaaaagga
    13741 atagagtgta aaacaaagcc aacatcttgc ccagaccaac tgtctctagc attggaaaat
    13801 tatatgaata taaagtaata cataaaacaa tcgattagtt aggagtttaa ttatgaaacc
    13861 aataataggg attttaggaa atttaataat aatggaaaat ggtatgtttc caggtcttga
    13921 aaggtcatat gtaaataatg attatataaa tgcagtgcta aaaggaggag gtagtccagt
    13981 aataattcct gtaaatacag ataaagaagt tataaaaaaa cagattgaaa tggttgatgg
    14041 agtcttaata tctgggggat gggatatcaa tcctcaactg tatggagaag aaacaagaga
    14101 agaaacgaca tttatatatc cagaagtgga tgaatttgat ttaattgcaa taagtatagc
    14161 attagaactt aaaaagccta tattaggtgt atgtagggga ctacaaattt taaatgtaag
    14221 tttaggagga actttatatc aagataataa tcttatagaa ggaagttata taaaacatac
    14281 acaatcttct aaaagacatg tagctactca taaagttgat gttaaagaag gaagtatttt
    14341 agagggaatt ttaggaaaac aattacttac aaatagttat catcatcaaa gtgtcaatca
    14401 gcttggaaaa ggattaaaag ccatagcata ctcaaaagat ggtataatag aagctattga
    14461 gaaagaggat gaaaattttg tagtaggagt acagtggcat ccagaaatga tggtagatta
    14521 ctgtgataaa atggaaaaac tatttaaata ttttataaat atttgttcaa atttataata
    14581 taccttgggg ggattgaaca tgaacgaaaa gaacaaaatg ggattaataa gtattatact
    14641 tttaggtatt aatgcagtag taggagctgg agtttttcta ttaccaggag atgcaatgaa
    14701 atcatttggt gtagcaagta tatttgtata tatatttgat atgttgttag ttttatctat
    14761 ggcattctgt tttgctgagg ttgcaggtaa attcaataaa aatggcgctg cctatgtata
    14821 tacaaaagaa gcttttggag atttttgtgg ttttgaagta ggtcttatga aatgggtaat
    14881 aggatgtatt tcttggggag ctttaatagt aggttttcct acatcattat cagcagtatg
    14941 ggctccagca ggtgaaccac atatacaaaa aattataatt gtagccatga tagttgggct
    15001 tacaattata aacttattag gtgtatctct atcaaaaatt gtacaaaatg ttataactgt
    15061 aggtaaacta attccattaa tactatttat aggaataggt atatttttta taaaaggagt
    15121 taattttacg tcttcaacaa tggtacctcc aggagctgga gcaacagagt ttggagcagc
    15181 agcactttta atgttttatt catttacagg atttgaatct atagcagttg cagcagaaga
    15241 tatggagaat ccacaaaaaa atataccaat agcaattata agtgtaatag taattgcatc
    15301 aataatatat atattaaatc aagttgtatg tgttggtata ctaggagatt cgttatctag
    15361 tacatctaca ccagtggcag atgctgcaag aatatgcttt ggaaatatgg gagctggatt
    15421 ggttaccttt ggaacattgg tttctgttgg tggaatttgt atgtgtggtg cttttgtaaa
    15481 tccaagaagc tgtgtagctt tagctgatga taaaatgtta ccgagaatat ttgcaagaaa
    15541 agataaaaaa ggtacaccat atgtagcgat aatagctact atgctaatca ctataccaat
    15601 agctctatct ggaagttttg ctgaattagc agcaataagt gcagttgcta gattcataca
    15661 atacatacca acatctttat ccgtattagt gtttagaaag aaaagaccag aattagtagg
    15721 tacttttaaa actccttttg gagcagtgat tcctctaatt gctgtatgtg ttggaacatg
    15781 gttgttattc caagcatcta tgcatcaatt aattatggga ttaggagctt tggcaattgg
    15841 agtaccatta tactttataa tgaagtctta taatagaaaa gtctatggtg aaaatttaaa
    15901 gaaaatagtt taattatgtt ataacagttt attgagttaa aattagacat tggcagaaaa
    15961 ttaaatacaa ataagtatct ataaggctat attaaaatat tattaatttt ttattttaat
    16021 atagccttat attgttatca ataaatgaaa aatattgtaa caacagaaga acaatagtat
    16081 tatgtttata gacaaaaaac ttattaggag gtaaatttat gccaacaata acattaaaaa
    16141 atggtgtaga cgtacttatt agagaaggag taagggaaga tgctcaaagc attatagatt
    16201 tttataatga agtgggtgga gaaactcatt ttctgtcatt tggaaaggat gaatataaaa
    16261 tatctttgga ggaacaagaa aatgctatag aatcagcaaa agcatccgat aattctgtta
    16321 aactgattgc atttatagat ggtgaaatag ttgggattgc aacgattgat tctaatcaaa
    16381 aagcaaaagg aaagcatgtt ggagtattag gaattgttgt aaaagaaaaa tattggggaa
    16441 ttggattggg taaaaggctt atgttagacc ttatagaatg gtgtaaatca aatggaataa
    16501 ccaagaagat aactcttgtc actaatgaag aaaattataa tgctatagga ttatacaaaa
    16561 aagttggatt tgaagtagaa agcatactaa agaaagaatg ttattataat ggtgtttata
    16621 ctgatttaat aggaatgtca cttttattgg gaatataatt agtgtacatt ttatctcgaa
    16681 aaaagtatat taagtatggt ataattaaaa aagaatataa cttaatataa ttttggagga
    16741 cgaattatga aaaatctgtg taaaatatca gatgattatt taaacagcaa gcttaagtat
    16801 ttaaagttat tatcaaaaca atatccaagt atatcaaaag caagtacaga aataataaat
    16861 ttagaggcta tattaaatct tccaaaggga acagagcatt ttataacaga tgtacatggt
    16921 gaatatgaac catttgtaca tgtattaaaa aatggttctg gtgtaataaa gagaaaaata
    16981 gaagaattgt tttcaaatac aataagagac agcgaaaaaa aaatgttagc aactcttgta
    17041 tattatcctg aacaaaagtt agacctaata attaagcaag aggaaaatat agatgatttt
    17101 tatagaataa atatttatag acttatagaa ctttgtaaat atgcttctag caaatatact
    17161 aggtctaaag ttagaaaact gttaccagaa aattttaaat acataataga agaacttttg
    17221 catgagcatg ttaaaagtga acataaagaa gagtattata aaagtatagt tgaaacaata
    17281 gttgacatag gaatagctaa ggagtttata attgctattt ctacagttat acaaaaattg
    17341 gttgtagata gacttcatgt aataggagat atttatgata gaggtccaag accagatata
    17401 attgtcgata agcttattga acatcattgt gtagatattc aatggggaaa tcatgatata
    17461 ttgtggatgg gtgcagcctc aggtgaaaaa acttgtatag caaatgcact gaggatatca
    17521 gctagatatg cgaatttaga cattgtagaa gacatatatg gaataaatct attgccttta
    17581 gccacttttg ctatagaaat gtataaagat gacccttgta aagaatttat tccaaaggtt
    17641 aatgaccaaa gtgtaacaac aacagaaaag tctttaatgg caaaaatgca caaagcaata
    17701 agtataattc aatttaagct tgaaggtgag gttataagac gaagacctga atttgaaatg
    17761 gaacatagac tcttgcttaa tatgataaac tatgatgaag gtacgattaa tttaaaaggt
    17821 aaaacatata aattaaaaga tacttattta cctacaatag acaaaaaaga cccatataaa
    17881 ttaactatgg aagaaagaaa tgttattgat aaattagtat cttcatttag aggtagtgaa
    17941 aaattacaaa aacatgtttc atttttgttt tctaaaggaa gtatatattt aaaggctaac
    18001 tcaaatttac tgattcatgg atgtgtaccg ttaaatgaag atggaagctt tatgtctatg
    18061 aatataatgg gaaaagagta taaaggtaag gctcttatgg ataagatgga gtctctagca
    18121 agagaaggat ttttctttaa agataaggca gaagaaaaac tgtatggcat ggatattatg
    18181 tggtatttat ggactgggaa atgttcatca ttatttggta aagatgatat gactacattt
    18241 gaaagatact ttatagctga aaaagagact cataaagaaa ataagaaccc atattttaaa
    18301 cttagagaaa atgagatggc ttgtaaaaga ttatttgaag aatttgattt agaacttgat
    18361 gaatctcata taataaatgg tcatgttcct gtggagagta aaaatggaga gagcccaata
    18421 aaagctaatg gtaaaattct cgttatagat ggtggttttt ctagggctta ccaaaaaact
    18481 actggtatag ctggatacac tttgatatac aattctagaa ctttgcaatt agtatcgcat
    18541 gaaccattta attctgctga agaagccatt gcaaatgaaa gtgatatctt atcgacaact
    18601 gttgtagtag agcataaggc aaagagaaaa atggtgagag atactgatga aggagtaaag
    18661 atacaagagg aaatagaaga tttaaaacta cttttaatgg cttataagaa agggctaata
    18721 aaagaaatgt agatgttata gaggcacttc atgattgaag tgtctttttg ttaatactta
    18781 ttaaatatat tataaagatt aataatagta gtttatatta tacttactaa gtgaatccaa
    18841 gataaatggg ttcacttttt ttatttataa acattattaa aaaaatatag atgttttggt
    18901 tatattcctt gtcctttata aatagaatta tataaacaaa ggaggaggac aagagatgaa
    18961 taaactttct gatgaaataa taaactctct ttctacaact ataagagaaa aggtagaaaa
    19021 agtctcaaac aataatctga acatagaaga aattaggtta cgctcacaaa aaccattgat
    19081 actaaatgca aactctaaag attattttta caatcaaaaa actatgacac ttgatttaaa
    19141 tcaacaaaac tcatatgtag taacaagaga agatgtagag caaacttttc aaataatatg
    19201 taaatattca atacattcat ttatggatga cataaaaaaa ggattcataa ctttgagagg
    19261 aggtcataga gtagggttag ttggaaaagc aatagtagaa gatggacaag tcaaaaatat
    19321 aaagcatata tcatctttaa atataagggt atcaagggaa attattggat gctcggataa
    19381 gattttaagt catatcataa agggaaaaaa tcagattaat aatactttga taatatcacc
    19441 acctcaatgt ggaaaaacaa ctttaataag agatatagta agaaatttaa gtaatggtaa
    19501 tgaagattat ggatttaaag gtttaaaagt ggctttagta gatgagcgta atgagatagc
    19561 aggagcttat ctaggtgttc cacaaatgga tgtgggaata aggactgata taatagaaac
    19621 ttgcccaaaa gacttgggta ttacaatgct tttaaggtct atgtcaccaa atgttattgt
    19681 gacagatgaa attggaagtg aaaaagaaat aaaggcatta tacacagcat taaatggagg
    19741 tataggatta ataactactg tgcatggaga ttcaatagag gatatacaaa atagaaaaga
    19801 attaaataga cttctggata aagagttatt taaaaaggtt ataattcttt ctgcaaaaag
    19861 aggagcagga acaattgaaa aaatttatga tttagaagaa aagagatggt attttgcaaa
    19921 ttaaaataat tattatagct ttcttgatag gaagtagtta tttgataggt gaacaaatat
    19981 acaaaactta tactcgtaga cataaacaat taaacgattt aataagagtt ttagaaattt
    20041 tgaggatgga tttatctttt ggactttata cattagaaga aatctttaat aggataggtg
    20101 gaaataaaga gttttgtttt tggaaatttt tctatcaaat atcagaagga cttcacaatg
    20161 aacaaagtaa aactttggaa ataataatat cagaaaatat tgatgtctta agtaaagaaa
    20221 cttatctagg caataaagaa attgaggaac tgaaaaatct aatacttact ttagggaaaa
    20281 gcgatataga gtcacaacaa agaatgatag atttatctat agaaaatttg aaaaaacaaa
    20341 cctatgagac aaaggaagat ataaacaaaa aaggcgtatt gtataaaaaa ttagtgacat
    20401 tcataggtat aggtatatgt attatattga tttaatatgg ggaggtttat tatggaaata
    20461 tcattgatat taaaggttgc aggtgtcggt attctaatat cagtattgaa tatgatattg
    20521 gaaaaaacag atagaaaaga ttgggcaggt cttactacat tagcaggtgt aataatcgta
    20581 ttgggtatgg taataacaga aataagtgac ttgtttaata ctgtaagaac aatgtttcaa
    20641 ctttactaaa gaggagggag taatttggaa ataatgcaat taataggaat tgcaatcatt
    20701 tcaactacac tctgtttagt aattaaaaaa gatagaccag agatagcaaa tttcatagct
    20761 ataataactg gagtaataat actattgtca gttatgttta agctaaattt tatagtagat
    20821 agtatacaag atttggctaa caaggctaac atcccgacta tgtatatatc attaataata
    20881 aaattaattg ggatagcata cttaatggaa tttgcgatac aactttgtaa agattgtggg
    20941 gaaggaaaca ttgcttcaaa actagaattt ggaggtaaaa taatagttat gtcaatgtct
    21001 ttccctatac ttttgtccat tgtagaaatg gtggtgaata taattccata gatgtgtatc
    21061 ttggaatgaa tataagtata ttagagagct ttcgttgtat tgaggtttat agagtgaaga
    21121 gaggcatggt tgcttatgaa aaaaagattt ttaccaatga ttataggttt tttatttact
    21181 ttcttttttg taaatatctt tgctattatg atatttgcta atgaagtacc aagtagtgaa
    21241 gataaagaat atggtgaaac aaaaaatagc atagataagt atatagatgg tcaattagac
    21301 aagctagata taaatgagat tcaagactat ataaataaag aaatagttat taatgatgtt
    21361 aatttaaaat catttgtaaa agatttaatt agtggagaaa aaaatatctt agatttattc
    21421 aataaagatg gattgaagat attgatgttt gatgaattta aagcaagttt aaaggtagta
    21481 gcagtaattt tggtactggc tctgttatca tctattttaa agagtctgga aaactctttt
    21541 tcatcaggtg cagtaagtca aatagcaaca tatataatat ttatcacaat ggtatcactt
    21601 acacttattg gttttaaaga tgtattacag atttgctatg atgcaataga ccatactgta
    21661 ggtcttatgc aagttataat gccaatatta ataacatttt tacttttaat tggattccca
    21721 ataacgtcga ctactttgaa tcctatcttc ataggaggag taacatttat aaatgtattt
    21781 tttaaaaatt ttctatttgt atctattact gttgcatttg gaattttaat aataaacaat
    21841 ttatcaaaaa atataaggct aaagagattt ttctcctttg taaaacaaat aaattatgtt
    21901 tctattggag ctatgtttac tgtttactta ggtcttgtat ccatacaagg actgtatgta
    21961 accagttttg ataaattcag tgtaaagact gctaaatttg ctataggtaa ttttattcct
    22021 gttgtaggtg gatttgtatc tgactctgtg gatattttat tatcttcatc tcagcttata
    22081 aaaaatatat ttggaggaat agggcttatc ttacttgttg gaatttgctt acttccagta
    22141 ataaaaattt tatcagtaat agtagtgtac aaattagcag caataattgt agagcctgtt
    22201 ggagaggatg gaatatctaa ttttttaaat gaagtggcaa atttaatgat aataatgcta
    22261 gcatcagtaa ttgctataac agtaatgttc tttgtaactg tagctatctt gacctcgata
    22321 agtgtcgtaa gtcaagggta atttatatat cagtgaaaaa taattacatt taatctaatg
    22381 tttttagaga ggaggatgct atgttagagg gcataaaggc atggatagtt agtgttttga
    22441 taggagcatt tatagtaaat atagtagata tgattttacc aagttctaag ataaaacctt
    22501 atgtcaacct agttttaaac tttatgtttg tatttattgt aataactcca gtagtaggat
    22561 ttttttcaaa agatatgagt ttagaagata gaatattaaa atctatggga aactacaaca
    22621 agcagtatgt agatagtaca aatgctttgg caaaagagac tggaaataat agtctatcca
    22681 agggatatga ggatgggtta aaagaagtac ttaaattaaa acttgatgaa tatggttatg
    22741 atttagaaga tatagagctt aatggggcaa atataaataa tataaaaata aaagaaaaga
    22801 ataatagtgc aaaaagtaat aacagttcca atgaagaaaa taaaaataat agtactaaaa
    22861 gagaggaaga aaacataaac tctaatgaca aagaaaattc taaacaagtc ttcaaaaaag
    22921 gtacagagta tgggttgaac ctaaatgaag aaaaattaaa aaacgactta ataaaggtgc
    22981 tggatgtttc tatagaagat atacaaattg ataaatagga gttgggagaa tgttgaaaaa
    23041 cttaaatgac aaagataaga gaaaggtata ttcactaata actatagcag gaatatgtgt
    23101 ggtttcatta gtattattat cttgttttcc tagtagcaaa agcgataaac aagttggaaa
    23161 aacagagact aataaaaatg ctgaaaagca agtcactaaa gaacaagaaa aagatgattt
    23221 agagtcaaaa ttaacagcaa tactatctaa aattgatggt gcaggagacg ttgatgtaat
    23281 ggttacattt gaatcaagtg aagaaataca acctgctttt aattcaaata atacaacaga
    23341 aacaacagag gaaaaagatg cacaaggtgg agaaagaaca gttacgactt ctagtgaaaa
    23401 taaaacaatg ataacttcaa attcaagtga ccctgtagtt ataaaaacta cagagccaaa
    23461 gataaaggga gtgatagtgg tagcaagtgg agcaagtgac ccaagtgtta aagagacact
    23521 ttatagtgca gtacaaacat cattacaagt agctggtcat caagtagaaa tatattctaa
    23581 ataaatacat ataaccgggg ggataaatga atgaagttta attataaggg aagaggattt
    23641 gtaataataa ctttaactgc aatgttagtg gtagtaggaa cagtgaatta tcaactaagt
    23701 aagaaatctt tattagaaac atcaaaagag tttaaggcat atgaagaagc acagttgcaa
    23761 aaaaatactg atgagagtga tagtagtaag acagaggatt ctagtaatat agataaacaa
    23821 gatggtaagg aaagtgctga tattgatata gttgatagca aagctagtaa agtaaaagaa
    23881 aaggcaactg agacaagtaa ggaaataaaa gctcaattat catcagagaa aaatatgaaa
    23941 aaggcatctt atattttaga tatgaaaatg aatagagaaa aacaaagaaa tgagttagtt
    24001 caagatttaa atgaaatgat aaataatcca tctacaacag aagaatctag aaaagaagct
    24061 tctaatatga aattaaatat agttaaaatt caagaaaaag aacttcaaat agaaaacctt
    24121 ttgagtacaa aagggtatga agaagcgtta gtttatataa gcgataacaa agttaatgta
    24181 gttgtaaatg aagctaaatt agaaaagaaa gatgcagcaa aaatatttga tttagttgca
    24241 gaacaagcca atgtgaagta tgaaaatatt aaacttacaa ataataatag taataagtaa
    24301 agtataaacc tcagaattaa ctgaggttat tttcttgcaa agtagacttg tatttggtat
    24361 tattatactt ataaaaatag ttccttaaaa tcaggaggta agttttaata tggaagataa
    24421 taaatttgga caagtaaaaa tatctaatga tgtaatagct acaatagctg gtttagcagc
    24481 attagaagtt gaaggcatag aaactacagc aacattaaca gataagttgt taaaaaataa
    24541 tggagtaaaa atacaaatcg aagaagagga tgttaattta gatgtaatgg ttacgataaa
    24601 gtatggaatg tcaataccag atacagcttt taaagttcaa gaaaatgtaa aaaatactgt
    24661 tgagacaatg acaggactga aggtttctca agtaaatata cacattcaag gaatcagctt
    24721 taagaaggat aaagttgata aagaagaagc aaaagcaact aagaaaaatt aatattagcc
    24781 ctctgaaaag tcagagggtt ttttgctggt aattgatttt atatggataa ttaaacttaa
    24841 aggagaattt tgattgatga aaaaagatag ggcacaaaag agtacaacaa gagaatatat
    24901 aatgaaactt atataccaaa taaatattaa taaagaagat tttgaaactt tagaagataa
    24961 agtagataat tttttaaaag ataattcaga acatattata aatagatata aagaacttgc
    25021 acttcaatac tcaaaaaata caaatttaaa gttagaagat actgaaattg aagatgttat
    25081 agacaaaaaa tatataaata cagtatgcaa agcattgaaa gaaaatcatg acaaaataga
    25141 tgagttaata aataagcatg ctaaaaactg gacagtagat agaatgccaa aggtagatgt
    25201 ttctatactt agattgtctg tgtgtgaaat actttattta gacactccta ataaagtatc
    25261 aataaatgaa gcagtagaac ttgcaaaaat atattgtgat gataagtctc ctaaatttat
    25321 aaatggtata ttgggaagtg ttgttgatga aattgggaaa taatataata attggaattg
    25381 atactagctg ctatactact tctatagcag ctatctcttt agataagaaa gttatattca
    25441 atgaaaaaat aatgttagaa gtaagggata attcaaaagg tttaaggcaa agtgaagctg
    25501 tatttcaaca tatcaataat ttagggattc ttagtgatag gataaaatct tttaaagata
    25561 agtttaatgt agaaggagtt tgctcatcaa aaaaaccgag acctgttgaa aactcatata
    25621 tgcctgtatt caatgtaggt cataattttg gaaaattatt gtctagtata tatggttgta
    25681 ggttttatga gactactcat caagagaatc atattgaagc aagtttatta aatagtaaat
    25741 taaaaaataa taataaattt atttctgttc atatgtctgg tggtactaca gagatacttt
    25801 taacaagcaa acaagatagt catcacaatg tatgtgatac taatttaggt aaaattgcca
    25861 aaataagtat taaaaaagat gataaaagta agttatacaa taattttgga tataatatag
    25921 atataattgg aggaagtaaa gatattagct ttggtcaact tatagataga gtaggaatta
    25981 agcttggata taaatttcct tcaggaaagt atttggatga aaatgcttta aattgtaatc
    26041 ttaaaataga aagtggtctg aaaacttctg taagagatgg gtatatgaat ttatcaggat
    26101 tagaaaatca ggtaaataag attataaatg ataatggata taatactaat caaaaagaat
    26161 atatatctaa attggtatta gattcagtag ttagaaatat gtttaaatct ttagtgtatt
    26221 tatgtgaaac ttataatgta aatgaagtag tatttgctgg tggagtttct gcaagtaagt
    26281 atattcttag agaattaagc gtgaagttaa gaaaaaagca tatagaagct tattttacag
    26341 aaccacaata ttcaactgat aatgctgtcg ggtgtgctat aataggattg aataactttt
    26401 taggagaaag agtatgaaac taagagcttt agatataagt gaagcaaact catatattaa
    26461 aagaatttta ataaacgacc caatactttc taatcttaaa gttaaaggag aaatttctaa
    26521 ttttaaggtt catagtagtg ggaatgtata tttatcactt aaagatgaaa catcaaagtt
    26581 aaactgtgta atttttaaaa gtaattttaa tcgcaattta aaattagata atggtgtaaa
    26641 aattatagct aatggatata tatcagtcta tgaaagagat ggtgcgtatc aattatacat
    26701 taatgaaatt gaaatagagg gaataggaaa tttgcacata gagtttaata gattaaagga
    26761 aaaacttaat aaagaaggat tatttgaccc taaatacaag atacctatac ctaaaatgcc
    26821 aaactcaatt ggcgttataa catctccaac aggtgctgtt ataagagata taataaatgt
    26881 aataaaaaga agatatccga aagttaatat aaagctttat ccagtaacgg ttcaaggaga
    26941 taaatcagct gaagaaatct gtgaagcaat tagatttttc aatcatatga agaatgttga
    27001 tacacttata gttggtagag gtgggggttc aatagaagaa ctttggtctt ttaatgatga
    27061 aatggtagca agagaggttt ttaattctca aattccgata atatcagcag ttgggcatga
    27121 aacggatttt actatttgtg actttgtgtc tgatatgaga gccccaacgc catcagcagc
    27181 agctgagatt gctactccat cattggatga tataaactat aaacttggaa acataaaaag
    27241 taggatgagt aagtctctta caaatcaaat agagctagac caatataggt tagaaacagt
    27301 atttaataag ataaataact atttagattc gtacacaata aaagataaag ttatacaatt
    27361 agacaaaata tatgataaaa taatttttgg aatagaaaat aatttaaaat tagaagatga
    27421 aaaattagta aaaattggag cattactcca taatttaagt ccattagcta ctatggatag
    27481 aggttatagt ataactcaaa aaaatggaaa agtaataaat agtataaaag gattaaaaat
    27541 aaaggatagt atagatatag tattaaaaga tggaaattta gaatgtatga tagataaaat
    27601 tgaaaataaa gagggatagt atgaatttaa cctacgaaga agcttataaa agattagaaa
    27661 gtattttaag tgaattagaa tctaaaaatg ctagcttgga tgaatcttta agcctatatg
    27721 aagaaggtat aagcctttat aaacattgta ataagctttt agatgatgct aaattgaaaa
    27781 taagtaaatt taatcaattg ggaatagaag aagactttaa aatagaggag gaataaaatt
    27841 ggaatttaaa caatgtctaa aagaaaaagc aagttttgta gaaaaagtac ttaaagaata
    27901 tatgcctaaa gaagaagggt atcaaaaaac tgttattgaa gctatgaact atagcttaag
    27961 tgctggaggt aaaagattaa gaccaatact tacattggag gcttgtaaaa tagttggagg
    28021 taatgaagat gaagctattc cttttgctat tgcaattgaa atgatacata catattcact
    28081 aatacatgat gatttgccag ctcttgataa tgatgattta agaagaggaa gaccaacaaa
    28141 tcataaagta tatggagaag ctatggggat tttagcagga gatgctttgt taaactatgc
    28201 ttttgaagta atgcttgcag gctcaatcaa taaagaaaat ccagaaaagt atctaaaagc
    28261 tataaatgaa attgccaaag gtgctggtat atatggaatg ataggtggtc aagtagtaga
    28321 tgtagaaagc gaaaataaac aaattgaaaa agaaaaatta gattatatac atatgaataa
    28381 aactgctgca atgatggtag gctgtatgag agcaggagct actataggtg gagcaaattc
    28441 tgaacaaatg gaagaaataa ctaaatatgc aaaaaatatc ggattatcat tccagatagt
    28501 agatgatata ctagacatag taggagatga agctaagtta ggtaaaaagg ttggaagtga
    28561 tatagaaaat cataagtcaa catacccatc tcttttaggt ttagataaat ctaaagaaat
    28621 tgcacataat ttgattgatg aagcaaagaa aagtatagaa aaattatctg atgatgtaga
    28681 ttttttaaag ggattggctg aatatataat agatagagaa tactaaaata tacagctaaa
    28741 atcgaggagg gaaaaatgga ttttttttcg gagattttta acaatggggc tttgggaata
    28801 agtctgattg cttgtttctt agcacaattt ataaaaatat ttactggtaa ggaaaaaaga
    28861 attgagttat caagaatact tatttcagga ggtatgccta gttcccatag ttcttttgtt
    28921 acaagtttag ctacagtggt aggtattgaa aaagggttta attctactga ttttgctata
    28981 attaccgtgc ttgccttaat tataatgtat gatgcagcag gtgttagacg ggctgttggt
    29041 aaacaagcta ctatattaaa tcaaatggtg gcagatatac agcatggaaa gcatatagag
    29101 cagaagaaat taaaagaatt aataggtcat acaccactag aagtttggtt tggagcttta
    29161 cttggaatag taacagcttt aatattgatg taaattgaaa atttacagaa taaaggtgag
    29221 gataatatgt ataaatattt agataaagta aattctccaa aggatataaa aaatatgagt
    29281 atagaagaaa tggatttact tgcaaaggat ataagaaagt tcttagtaaa atctgtttca
    29341 aagacaggag gacacttagc ttctaatcta ggagtggttg agttaacatt agcacttcat
    29401 aaagtatttg atagccctaa agataagatt gtatgggatg tagggcatca atcttatgtt
    29461 cataaaatag ttactggaag aaaagattgt tttgtatctt tgagacagtt taatggacta
    29521 agtggttttc caaaggagaa tgaaagtcct catgatattt ttgatacagg acatagcagt
    29581 acatctattt ctatagctac aggtattgcc tgtgctaggg atataaaaaa agaaaactat
    29641 agtgttatat ctgtgatagg agatggttct ataacaggag gtatggcact tgaagcttta
    29701 aatcaattag gatatataga taccaatatg atagtaatcc ttaatgataa tgagatgtcc
    29761 atagataaaa atgttggagg aatgtctaaa tatctgtcaa gtattataag aaactcaaca
    29821 gttgagaaaa tgacagatga agttgataaa attttaaatg ttacacaaac aggtgaaatt
    29881 ttatctaaga ctgcacatag atttaaagat aaactaatgt atagcttttc tcctcaggac
    29941 tgttcatttt ttgattcatt aggtataaga tattatggac ctatagatgg ccataatact
    30001 aaagaactaa tagatatatt gagaaaagct aaacacaaaa aagggcctgt tcttttacat
    30061 gtaattacga aaaaaggaaa agggtacaga tttgcagaag aacaacctga taaatatcat
    30121 ggagtatcaa agtttgatat aaagacaggt gttacatctg caaaagttaa gtctatgtca
    30181 attagtgttg gagaaaaact tgttgatatg gctaatagta atgaaaatat agtagcaata
    30241 acagctgcaa tgccatctgg tacagggtta aacctgtttg aaagtgcata tccaaaaaga
    30301 tattatgatg ttggtatagc tgaacaacat gcaacaggat ttgcagcagg tcttgcaaaa
    30361 aatggtatga aaccttactt tgctgtgtac tcatcatttt tgcaaagggc atatgaccaa
    30421 gttattcatg atgtatgcat aacaaaaaag ccagttactt ttcttataga tagagctgga
    30481 ttagttggaa atgatggaga aactcatcat ggtatgtttg atttaagtta cttaaattct
    30541 attccaaata ttgtagtaat ggctccaaaa gacacaagag agatggagct tatgatggat
    30601 ttgtcattaa aattagattg tccactagca attagatacc caagaggaag tagttattac
    30661 ctagataagg gagagtatgg agagattgta ctgggtaaat atgaggtatt agatgacggt
    30721 caagatacag tcatactttg tattggaagt atggtaaaac atgctttaga ggctaaagaa
    30781 atattatcaa gagaaggaat aaatccgaca atagttaatg ctagattctt aaagccaatt
    30841 gatgaaggta tgttaaaagc attattaaaa aatcataaaa atgtagttac tatagaggat
    30901 aatattgtaa ctggaggatt tggaagtaga ataaataagt ttattataga taatgaatat
    30961 aacgtaaata tacttaatat agcaatacca gaagaatttg taaaacatgg caatatagat
    31021 gaattatatg attttgtagg attatcgcca aaaagtattg ctgataaaat aaggaaatta
    31081 gttattgagt aaaaatctaa tgtagatatt gtaaattaaa atttatataa aatatagaat
    31141 ttatcaatta gaataaatat caagtgtgtt acttcaagct actttagtta tcattaaagt
    31201 agcttttaac agaaaggtaa ttgtatgaaa aaaagaatag atttattatt agtagaacaa
    31261 gggtactttg aaagtagaga aagagccaaa aaagcaataa tggctggatt ggtttttgtt
    31321 gataatcaaa ggtgtgataa ggctggtaca gaagtaaaag aagattgtag tatagaagta
    31381 aaaggaaatc caataccata tgtcagtaga ggtggtttaa agcttgaaaa agcaatgaaa
    31441 aactttgatt tgactattga tggaaaggta tgtatggata taggggcatc cacaggtggt
    31501 tttacagatt gtatgctcaa aaatggagca ataaaagtat tttctataga tgttggttat
    31561 ggtcaacttg catggaaatt gagacaagat gatagggttg tgtgtatgga aagaaccaat
    31621 ataagaaatg tgacaataga agatacaaag cagtttgctg attttgcgtc aattgatgtg
    31681 tcttttatat cgttaaagtt agtacttcca aaggcaaagg agttagtacg tcatgatggg
    31741 gaagttgtcg ctttaattaa acctcaattt gaagcaggaa gagaaaaagt aggtaaaaaa
    31801 ggagtagtta gagaaaaatc tacacatata gaagttataa aaatgatttc tgatttctca
    31861 gtcgaaaatg gatttgagat tttagggtta gatttttctc ctattaaagg tcctgaaggt
    31921 aatatagaat atctaattca tttgagaaat ggaaatgaag gatatgaatt tgatggtgag
    31981 acatacaata acaaaatagt agaagttgtt gaagcttctc ataatttaga caaataggtt
    32041 aaaagggggc ttagatttga tcctcgaatt atatatgaaa aattgtgcct tagttgaaga
    32101 actaaggttg aatattgata aaaacttaaa tatacttaca ggtgaaactg gttcaggaaa
    32161 atctataata atagatgcac ttggactttg tttaggtgat aaatatgata ggtctttttt
    32221 aagaaaagga acagataagg gacttgttga ggctgtattt ttttcagaca atagatatct
    32281 taaaaaaata ttagaagaaa atgatataag tatggaagat gataatttat tggtaataac
    32341 taggttgata tactcagatg gtaagagtac tgctagagta aatggaagga ctgttaaagt
    32401 gtctcttctt aaagaaattg catctacact tatagatata catggtcaac atcaaaatca
    32461 agctttgttt aataaagata ctcatttaaa atttctagac ctttttggag aaaatgaatt
    32521 ggaagagttt aaaattgctt ataaaaatgt gtaccataag tatagtgaag taaaaaaagc
    32581 tttaaattgc ttgacagaaa ataaagatga gatgcaaatt caacgagaaa tagatttatt
    32641 aagatttcaa ataaatgaaa ttgaagctgc aaatctaaat aagaatgaat atgaagattt
    32701 attaaaacaa agagaagttt atagaaatag tgaaaagata tataataatc taaattcgag
    32761 ttatagcaag ttacataatg gtgagtataa tgttattgac ctaataggtc ttgcatctaa
    32821 ggaacttaat gacatatcta aatatgacag tgttttaagt gaatatagtg atactgtaga
    32881 aagaatcatg tatgagttac aagacatatc tggtgagata agaaattaca aagataatat
    32941 agactttgaa ccttatgagc tagagcagat tgagcttaga atcgacgaga ttaataactt
    33001 aagaagaaaa tatggagaca gtatagatga tatatttgag tattatggaa aaattaaaga
    33061 tagattagat gaaatattaa acagagatga aagagttgaa cagttaagaa gcaaactgat
    33121 gaatatagaa gaagatttaa aaataaaagc cagtaaattg actaaagcaa gaatagaagt
    33181 agcaactact ttagaaaaaa tacttcttga tgaattaaaa agcttaaata tgaaaaatgt
    33241 aatgttcaag gttaattttg aaaaaggtcc atttacttta gatggagtag atgatattga
    33301 atttatgata tcttttaact taggagaaga tattaagcct atatataaag ttgcatcagg
    33361 tggtgagatg tccagattta tgttagcgtt taaaaccata ttggctgata tagatgatat
    33421 tgatacatta gtgtttgacg agatagatac tggaataagt gggatagcag cacagatagt
    33481 tggtgagaaa ttgagtgata tagcaaagaa aaaacagata atatgtataa ctcatttacc
    33541 tcaaattgct gcaaatgcag acactcatta ttgtatagag aaagatactt caaataatag
    33601 gacgtttacc aatgttagta agttaaatga atctcaacga aaaaatgaaa ttgccagact
    33661 tatagcaggt aacaatataa cagaaaaaac tattgaacat gcaagtgaaa ttattgagtt
    33721 ggctaaaaaa tgttagtgaa aaacaagcat tttaataggt gtaaagaatt tttatagaaa
    33781 tgctttacat ctatttttta tgatgaaatt attttaaaat atctagtgcc tatattgaag
    33841 aaaagtagat ttaaaaatag aagaaaattt gtataaattt gtaactttga aatttctaaa
    33901 tgcttaagta taatattatt tattaaggta gtagtgaggg ggacataaaa tgaataaaaa
    33961 agatactatg cacttaattt ttacaattgt aatttttatt ttattatggt atattgtggt
    34021 agcagtaagt gagattaata aaaatattga aagttgtagt aataaattag attatttgtc
    34081 acaagagatt atgagtacta aatcggatat tagtaatact ataaatgaag aaatgtcaaa
    34141 aagttatata acaaagagta ttgacttaaa agtaaaaaaa atcgagaaaa aagagtgtgt
    34201 tattgatgta gatgttcaat taagtaaact tggaaaaaat ggaaaagtat tttttatgta
    34261 taaagaagat agtgataaat ggaatgaaac tgagatgaca aaacatggag aattatcata
    34321 tgcatgtgaa attaagataa atacaggaag tgaatatgac tataaagtag ttacaagtgg
    34381 agctatatct gaaagttctg atgtgcaaaa attgactaaa tctgattata tgcctgaaca
    34441 acccatattt aattctggga taagagataa tagagaatac tttattgaaa tagtagaaaa
    34501 tagtaatctt ttcaatcatg agagtgaaaa gtcaaaaaat aaagtttatg ataatattag
    34561 attagaaaaa gtagatatta ttgtaaatga aggaaaaaaa gacactatat acaaagccaa
    34621 attagctgaa ggcttagatg atggcaaaac taataattca aatagaaatc aagtgaatta
    34681 tgaagtaagt tttcctaaaa gggatattga tgacataatt tatattaaag ctaaacttac
    34741 atacaataat ggagtagaat atacaaagga tataactgaa gatataacta tgggattaca
    34801 agatttagaa aaataaatac atatttaaat aaatattcaa atagatttgt tcaataaaat
    34861 agagtataaa taaaactgta gtagttttac ttatactcta ttaaaaaatt ataattttaa
    34921 ttccatatat ctagcccctt caattggatt ataagtataa ggttctatat cataaaaacc
    34981 aaacttttca tataatcctt gtgcactttt catgcttgga agagtatcta atctcatgtg
    35041 tgtatatcca aattttttag cttcttcaat gatttcttcc aatagtattt ttcctatttt
    35101 taatcctcta aattgatttc ttacatataa tctttttaat tcacatattt taccttcaag
    35161 tttttttaaa gcaacacaac ctgccaaatt ttcatcaaca aatgccaata tcaatgagcc
    35221 tgaaggtttt ttatattttc ctggaagtgt ttttaattca ttattaaagt cttgaaaaca
    35281 taagtctata tttagagaat ttgaatattc agtaaataga agttttacgt tttcaaggtt
    35341 ttctaaatct ttttcttcaa caaattgtaa agttatattt tgagccattt tatccgccat
    35401 tatataaaca tgtttatata atgacttcac ctccttgata tatgtatatt tttcttaata
    35461 tcaattagat tttaatacca ttactttttc accaccatag tcaagctctc cattaaactc
    35521 aaatccaaaa tctttataaa gcttaatagc cattttattg tcttcgaata tactaagata
    35581 tagttcatca cagttatatt catttttaag atgatttaca agaaaatcta atgatgcttt
    35641 tccatatcct ttaccttgat attttgaatc aatcataaat ctatcaagcc aaactctatc
    35701 atcttctaaa cgaccataca tagcaaatcc tattaaagaa ttttcatcat atattccaac
    35761 aggtacccaa gctgttataa atttagattc agcaatagaa agtgcattgc tttctatata
    35821 atctaactga cttttatcta cagacaaact aactaaatca tgccaattat ttatgtctgc
    35881 aattcttaca tttaatttca agatattacc gcccttcaaa ctttttgtta caatctaata
    35941 ctatcatatt atgtattaaa aatcacttat taagatttta aataaacttt ttaaatgaat
    36001 aaattctcag gaaaaaggaa ttataaatac ataataatac agcataggag tagatggata
    36061 tatgaacaaa ataaataaaa atttcaaaaa tatttggata atattaggag ctgtatcgat
    36121 ttttaccatg gttataattt ttaataaaaa ttgtaatgtt aataaagaga ctcaaataga
    36181 agcttttaca attaagaatc atgataaaaa atttgtatat cctatgggaa atataattgg
    36241 agtaaaagca aatacagatg gtgtattggt cttaggatat gaggaagagg atgtagacta
    36301 tattggaggc atacaaatcg gtgataatat agtaaaaata gataataaaa ggataaaaaa
    36361 tagtcaagat gtatcagaga ttttgaataa gattaaaaaa agtaaagttg aagtgacttt
    36421 tgagagaaaa aataagtata aaacagaagt aatagagact aaaaaagaaa atggcaagta
    36481 taaacttgga ttatgggtaa gagataaaat atctggaatt ggaactatga ctttttacga
    36541 ccctagtatg gaaaagttca aagcaatcgg tcatgccata aaagattcgg atactaatga
    36601 actattaaag ataaagcaag gatatatata taagccagaa caattaaaaa tagtaaaagc
    36661 tagtaatgaa aaagtaggta aaataaaagg agattttaat gacagcaatt taatgggtaa
    36721 tttctcaaat aattcagagt taggtataag tggtaatatt acagaaaacc ataataaaga
    36781 gtttaatgta gcaaataaag aaaagcaatt aatagaagtt ggaagaccgc aagatgtaaa
    36841 aataggagat gcagtaattc tttttgagga taaaaacaaa aatataacaa gctatgatat
    36901 aaaaatagaa agtatagtat atgataaagg aaattataga gatatggtaa taaaagtagt
    36961 agatgacaag ttattggaat acacaggagg tatcgtacag gggatgagtg gagctccaat
    37021 aatacaaaat aataaaatta ttggtgcaat aactcatgtt tttagagata atccgaaaaa
    37081 aggatatggt atttttatag atgaaatgat aaaattgtag gtgaggcatt aaaaaatttt
    37141 attattttat caattatcta ggaggaatat aattttggag tgtcgaatat gctttagagt
    37201 agataattag gaagcaattg tgtaaaaagt ttagttttct gtaataagaa gatgtttttt
    37261 aatgggggga tttttagtgg aaaaaatcaa aatagtttta gcagatgaca ataaggattt
    37321 ttgtcaggta ttaaaagagt atttgtctaa tgaagatgat atcgatatat taggcatagc
    37381 taaggatgga attgaagcat tagacttagt aaaaaagaca caaccggact tattaatact
    37441 agatgtaata atgccacatc tagatggatt aggtgtaatt gaaaaattga atactatgga
    37501 tatacctaaa atgccaaaaa taatagtact atcagcagta ggtcaagata agataactca
    37561 aagcgcaata aatctaggag cagattacta catagtaaag ccatttgatt ttgttgtgtt
    37621 tataaacaga attagagagc tagtttctaa tagagttaca caagttgagc caaaacctag
    37681 accagttcaa gagactcaaa tgactagaag tgattttgtt aagaatgtag gaaatataga
    37741 gacagaaatc acaaatataa tacatgaaat aggagtacca gctcatataa aaggatattt
    37801 atatttaaga gaagcaataa aaatggttat tgataatgtt gagcttttag gtgcagtaac
    37861 aaaagagtta tatccaagta tagctaaaaa attcaataca acaccaagta gagttgaaag
    37921 agcaataaga catgcaatag aggttgcatg gagtagagga aaagttgaca caataaatca
    37981 attatttgga tatacggtac acaatactaa aggaaaacca actaattcag aatttatagc
    38041 aatgattgct gataaattaa gactagaaca tagtatggtt aaataaacaa gacataaaaa
    38101 gtaaggcttt ttaattaagg cattggctat aaatgcgtat tacaagcagc gaaacggtat
    38161 aaccactagg gttataccgt ttcgctattt taataaatat aaaaattttc tttattattt
    38221 gcttactata tcaatataat aattttatta tactatggat atagtatgtg tctttacaag
    38281 ttgtaaactg acagtggttt attttttaat ataaatattg actttgatgc aggtaaactt
    38341 tgtattttta agcgtattat ggaatatgtt aaataaaaaa atgatgaaat atagtattgt
    38401 aaatgccaaa gatgcaaaac aaacttaaaa catttatttt attgttaagt aatgctataa
    38461 tataatgtga ttttaataat gatagtggag gtttaaatat gagagtcgag gcccctataa
    38521 aagtagatcg aaaaaccaaa aaacttgcta aaagagttga aagtggggaa atagcagtta
    38581 taaatcatat agacatagat gaagttgctg caaactcttt agtagaagct aaaataaaac
    38641 ttgtcataaa tgcggctcct tctataagtg gtaggtatcc caataaaggt ccagggatat
    38701 taactgaaaa taatatacta ataattgata atgttggaga agagttattt gaagaattaa
    38761 aagaaggaga aactatagaa gttgtagatg gaaagatata tagaaaagga aaatttttag
    38821 gtgcaggaga agttttagac aagtatgagg tttcacacca aataaaggct gcctatgaga
    38881 atttagctgt agaattggat agatttatag ataatactat agattatgct aaaaaagaaa
    38941 aaggatttat acttggagaa gtagaaattc caaaagtgaa aactaattat gctaataaac
    39001 atgtattgat agttgtaaga ggtcaggact acaaagaaga tttaagtact atgctttctt
    39061 atatagaaga ggtaaagcca gtattggttg gtgttgatgg aggagcagac gctttaattg
    39121 agtttggata tactccagat gtgattgtag gtgatatgga tagtgtaagt gatgaagctt
    39181 taaaaaaggc tagtgaaata gtagtacatg cttatacaga tggaagagca ccaggtctta
    39241 aaagggttga ggaattaggc ttagatgcag ttgtatttcc tgcaccagga actagtgaag
    39301 atatagctat gcttatcgct tatgagtata aggctgagtt aatagtagca gttggtacac
    39361 attcaaatat gattgatttt cttgaaaaag gaagaaaagg tatggcaagt acttttttag
    39421 ttagactaaa aataggttca aagcttatag atgctaaagg cgttaatttg ttatacagaa
    39481 gtaaattaaa aataaagtac atatgggcat taatagcaac agcattattt cctgtgttgg
    39541 tagttgcatc attgtcacca ggagttcaac agttcataca actaatgcaa ttaaagttta
    39601 gagtattatt acagatgtaa attttaggag gataaatatg catattaata tgaaatatta
    39661 tatagtcact ataggggcta tatttatagc tttgggtata ggcatgttag taggatttaa
    39721 tttaaataat aatcaacaat taagtgaaca acaagcaaat ataataaatg atttggatga
    39781 taagtttgat atcttaaaag aaaaaaatga taaacttgac agtgacttag caagtgtaaa
    39841 tagagattat gaagaggcag ttaattttat aaataaaaat gtagataaga ttttagctgg
    39901 ttcgctgaat ggtaagagta taggaataat atctgctaat gaaaatgacg attatacaaa
    39961 aaatatagaa gacataataa ataaatctaa tggaagcatt gcatttaata taatattaaa
    40021 agaaaacata acaaatccag aaaagttaaa ggaaatgtca actaaactag gtacagatgt
    40081 aaaaaatgca aatgatgcag ttaattatat aattgacact cttaaaaagg aagatgcaag
    40141 tgacatttta acatatcttc aagaactaga tgtaataaag tttaatttta ttggagatac
    40201 atatctaaaa tatgattccg ttgtaatagc tggtggaaat gatgcaaaag acagtgcaaa
    40261 acagtttgaa aaaatagaaa aatttgtagt ttcaaaactt aaatcagaga ataaatattt
    40321 agtagaagtt caaaatacag gagttaaaac ttcttatgta gaactatatt ctaaaaacaa
    40381 agttgcaact atagacaata ttgatgaagg tataggaagt atatctctag cgattcttct
    40441 acaacaaggt aatatagttg gtaattttgg tagattggat actgcaactt cattgttgcc
    40501 atctattaaa tagaaataat tttaaggaga gaaaaaatgg attcttatat aagtataata
    40561 ataccagctt ataatgaaga aagtagaata aaatatacat tagaaagcat attggacatt
    40621 aagcaaataa atgaaataat agttgtggat gatggttcaa ttgacaatac tgctaaggtt
    40681 gtatctgagc tagaaaatga aaagattaaa ttttttaagt tagataaaaa tagaggtaaa
    40741 ggatatgctt taaattatgg tatcaaatta gcaatgaaaa atgcagatat tataggtttt
    40801 ctggatggag atttaggaag ttctgctaaa gaagttgaaa aattaatagt acctatatta
    40861 aatggtgagg cggatgttac aatagccaag tttcctcctg caaagagaaa aggaggtttg
    40921 ggatttgtaa aaggtttagc taaaaattct gtgtttgaga tgactggtgt tgagttagat
    40981 gcaactttgt caggtcaaag aatatttaaa agagaagttt tagaaaagtt tgatgaaata
    41041 ccttttggat atggagtaga agttggaatg accattgata tattaaagta tggatttaaa
    41101 attaaagaag tattagtaaa tatgactcat aatgaaacag gaagaaattt aaaaggtttt
    41161 attcatagag ggaaacagta ttatcacata aaaaaggttt taggacaaaa aaagaaagaa
    41221 tggaggtaat atcttagtga aagattatat actttatacc attttattat taactggatt
    41281 atttggaacc tatgctgtaa ttccactatt taaaaattta ttgataaatg gaaatgtact
    41341 tagaccaaac tataaaaaag atatgatacc agtaagtatg ggaattgtat ttttgcctat
    41401 gattgtaatc aatggaataa tacttgcttt ctttactaca gaatttaagg atttagcgta
    41461 tatatttatg tttatgtttg gtatgatatc catgtttttt gcagggatac tagatgatgt
    41521 cattggaaat agagatgtaa gtggtttaaa ggggcatttt aaaagtttat ttaaaggaag
    41581 tcttacaaca ggaggtttta aagctttatt tggtggattt gtagggctta tagtttctgt
    41641 tgctatatca aaagacataa ttgatataat agtaaataca ctaataatag ctctatcaac
    41701 taatttaatg aatcttttgg atttaagacc aggaagggca ataaaagcat atttattcat
    41761 aatggtaatt atatttttaa cattgacagg atttgttcaa gttcttccat tacttatagt
    41821 accaaatgta cttgcatact ttaattatga tttaaaagca agggctatga tgggagatac
    41881 tggttcaaac gttcttggaa tatctattgg aatgctcatt tcttttgggt atccatttaa
    41941 cattagatta ggatggttaa tatttgtagt tattatgcat atattcactg agaaatactc
    42001 attaactaag ataatagaaa aaaataaact attaaatttt atagataaat tgggaaggta
    42061 gtattatgat aagcaaaaga gtggggattg ttgaatcaat agtaagtcaa actgaaactc
    42121 tagatgatat aagagtaaat ataaatggag aaatacaaaa ggcatataat tatccaaaaa
    42181 tatctggaac tataaatata ggtgacgaag tggttttaaa tacaacagca gtagaactga
    42241 gcttaggtac aggtggatac cattttgtaa taactaattt aaataatata gaatctactt
    42301 taactgaagg tggacatata atgaaactta gatatacgcc tcttcaaata aaagtggatt
    42361 ctgttgagga acaagaaagt atttatcatg ataaatttgc gaattttaaa ggattagaag
    42421 gtctttctgt tgtagtaggg actcttcata gtatgttaac tccatttgca gcttcattta
    42481 aaagaaataa tccaaataaa aaattagtgt atataatgac tgacggagca tctcttccaa
    42541 tttatttaag taaaaatgtg gatactttaa aagaaaaaaa attaatagat agtacaataa
    42601 ctataggaaa tgcgtttggt ggagattatg aatgtataaa tatatatact gcattaatta
    42661 cagcaaaaga aatactaaaa gcggatgcag tatttgtcag tatgggacct ggaattgctg
    42721 ggacaggaac aaaatatgga tttacaggga ttgaacaagg ctctattctt gatgccgtaa
    42781 aaaaacttga aggaagagca attgcaattc caagaattag ttttgctgac aaacgagaaa
    42841 gacatcaagg tatttcacat catagtatga ctgtatttaa agaaattgta aatgtaaatg
    42901 tagacatacc aataactata tatgatgatg aaaaattgaa ctttataaaa gagcaaatca
    42961 atttaaatgg tttagacaaa aagcataata taatttatat agataataat aaaacgaaag
    43021 aggatttaga ctattttaat ctaaaagtaa agagtatggg aagaaattat gaacaagatg
    43081 aggcattttt caaagctgca agcacagcag catattactt aatggaggtt taagatggta
    43141 ttagaagaaa aaactattag tagtgatagg gtttatacag gtaaagtaat tactttaaag
    43201 gttgatactg ttgaaattcc agggcaagga tatcaaaaaa gggagttagt agaagttggt
    43261 ggagcagtag gaatagttgc aatcacagat gataataaag ttgtgttagt taagcaattt
    43321 agaaaaccta tagaaaagcc aatctttgaa attccagctg gtaaactaga aaaaaatgaa
    43381 agtccaaaag aatgtgctga aagagaatta aaagaagaaa ctgggtatag tgcaaaaaat
    43441 attaagctaa tacataaatt tttcacttca gcaggttttt ctaatgagat aatgtttgta
    43501 tatttagcaa caggtcttac tccaggagag aataatttag atgcagatga gtttttagat
    43561 gtctatgaaa ttgagcttga agaagcatat aacatggtat taaaaaatga cgttgaagat
    43621 gcaaaaacat ctattggatt attattagta aaagatatgt ttaaaaatta atatttataa
    43681 aatgaataac cctttgtcct aaagcatatt attttataaa ggacaagggg gaattaaatt
    43741 gagaagaaca tatagaaaaa atgattttag agaattaaat agacaaataa ttattatagg
    43801 attgttgttt atgatgtcta ttgttgttgg gtcttacata aataaaatat tgccaggttc
    43861 tagtaacaat atattaaaca atataaatcc tgctgtagag tattataatc taaatataag
    43921 cataaaagat acagtgatac aaaatttaaa atcagatgca atctttatgg gctcaatagc
    43981 tctattaagt ctatttgtag taacaattcc agcagtgttg gtagcttttg tattaaaagg
    44041 gatgtcaatt ggttatacaa taaatagttg tatattggca ttaaaattta aaagtataaa
    44101 aatgatttta ataatattat ttaaaaattt gattattatt ccatgtgcaa tcatattagc
    44161 attaattagt ttaagttatt ttaaagaaat ggtttatgaa tttaaaaaga aaaatagaaa
    44221 aaatatgcaa tttttaatta agaggtatat actaaatatt ataattataa tagcactatc
    44281 attggggttg caattaatat taaatactgc aagtattggt attattaagt tcctagctaa
    44341 ataaaggagt ttataatgga tattatagag ggatatatag attacataaa agataaaaaa
    44401 aaattatcag agaatacagt ggcatcatac tttatggata taaaaaaata tatggaatat
    44461 ataaatcaaa aaagcattaa actagtagat atagtagaaa atgatattat aagttactta
    44521 ataaagttgg aaaaagataa tgtatcaata gctacaatag cgaggatgat atcctctata
    44581 aaatcttttc atgattattt atttttaaat catatatgta caaataatcc tgcaaaggat
    44641 ataaaaaaac ctaaaataaa aaaagaaaat ataaatatac ttacagaaga agaaattgaa
    44701 agactattaa attttccaaa gttaacaaca cctaaattga ttagggacaa ggctattttt
    44761 gaagtattat atggtactgg tataaaagta tctgaattag tagagatgaa tatagaggat
    44821 attgacctag atattgatta tatatattgt aattcatgtt gtaaaaatca aagagtgata
    44881 ccactttgtg atattacaaa actttactta gaaaagtatc taaaagaagc aagacctaaa
    44941 atggctgtag aaggtgaaaa atcattattc gtaagttcat taggtcaaag gtttacacga
    45001 caaggtcttt ggaaagtcat aaaaaaatat tctaatctag ccaatataga taaaaatata
    45061 aatcctacaa tgcttagaca ttcatttgct attcatttgt taaatgaagg tgctaacatt
    45121 gctgttgtaa gtaaaatttt aggaaatgtt aatttatcta gtttgcaagt atatttaaat
    45181 catatagata aaaacgtgag aagagaaata aaggagaaac atcctagaaa tgatgttgat
    45241 gtagaattac aaaaagcaga agctaaatag actatatagc aaattttata atttagaagg
    45301 agcatattta tatgagcaga gtaatttgga ttgtaattga tagtgttggg ataggagcat
    45361 tgcctgatgc tgaaaaattt ggtgatagta aggatgtaag tacccttgga aatatattta
    45421 aggaatatcc agatattcag attcctaata tgagaaattt aggtatagga aacatagatg
    45481 gtatagattt ttttgaaagt ataaaagaac caataggttg ttttggaaag tgtaaggaaa
    45541 tgtctcaggg aaaagatact actacaggtc attgggaaat gactggtata atagttgaca
    45601 aaccatttaa gacatttgaa catggattct ctaaggagat aatagaagag tttgagaaaa
    45661 aaactggaag aaaagtagta ggaaataaac cagcttcagg aactgtaata atagatgagt
    45721 atggagaaca tcaaataaaa actggagatg taatagtata tacatcagct gatagtgtat
    45781 ttcagattgc tgctaatgaa gaagtaattc ccctagaaga actctataat atgtgcaaaa
    45841 tcgctaggga aataatgatg ggggataatg cagtagctag agtaattgct agaccattca
    45901 taggtaagaa aaaaggtgag tttgtgagga cttcaaatag aagagattat tcactagacc
    45961 catttgaacc aacagttctt gataatataa aagaatcagg acttgatgtt ttagcagttg
    46021 gaaaaataga agatattttt aatggaaaag gaattacaga tgctatccac actaaaagca
    46081 atatggatgg agtggatgaa actttaaatt atatgaaaca agataataaa ggtctaatat
    46141 attcaaatct cgttgatttt gattctaaat atggtcatag gagagaccca gaaggatata
    46201 agaaagctct tgaagagttt gatagtagac ttcctgaaat aatggctaat atgagagaag
    46261 atgatatttt aataatcaat gcagaccatg gaaatgaccc aacatataaa ggtacagacc
    46321 atacaagaga atatatacct gttatgattt atggcaataa gattaaaaaa ggttttaatt
    46381 taggagtaaa agatactttt gctgatattg gagcaactgt tgcagatata ctaaatgtaa
    46441 agttgcctaa acatgggtca agctttaaag aagatttatt ttaaactata aaatgataaa
    46501 aacttagctt aataggatgg agagattgga atgtttgaaa agatagcaca aagtagtaaa
    46561 tttataaatt ctaaaagtga tataaaacct aagattggtt tgatattagg ttctggacta
    46621 ggtgatttag caaatgatat agaagaccct gtcgcaatta aatatagtga aattccaaac
    46681 ttccctgtat caacagtagc aggacatgct ggacaacttg taattggaaa acttgaagga
    46741 aaagaagtta ttgctatgca aggtagattt cattactatg aaggatattc tcagaaagaa
    46801 gctacttttc cagtaagggt tatgaaagaa ttaggagtcg agattcttat agtaactaac
    46861 gctgctggag gcgtaaataa agaatttaaa gcaggagatt tgatgcttat aagagaccat
    46921 ataaacttta gtggaagtaa tccattagta ggaaaaaatg atgacagatt tggtgctaga
    46981 tttccagata tgtcagatgc atattcttct aaatatgtag atgtagttaa aaactgcgct
    47041 aaagaatgca atatagatgt caaagaaggc gtttatatgt tttttagtgg tccaaactat
    47101 gaaacaccag cagaagtgag aatggcacaa attttgggag ctgatgctgt aggtatgtct
    47161 actgttccag aagtcatagt agcttctcac tctaatatag gagttattgg tatatcttgt
    47221 ataacaaata tggctgctgg catcttaaat caaccactaa gtcatgagga agtaatagaa
    47281 actactcaaa aagttaaatc agaatttatg aatttagtta aaacaacggt taaaaattta
    47341 taagttaaag cttattatag attttttgag gaagtttata ataaaatagt taatgtttaa
    47401 tttgaaaaga attaataaaa agctgtcttg atatagaaag ttatttctaa taaaggacag
    47461 tttttttata atactacaac atttgaaagt gttttaaagt ttaatattta tttaaattat
    47521 tataggttag aatggagatt tcaattatga gaatgtatga tattataaaa aaaaagagag
    47581 ataacctaga gcttagtaaa aaagagataa actactttat agaaaactat tcaaagggag
    47641 atatacctga ctatcaagct tctgcactat taatgtcgat ttatttaaat aagatgaata
    47701 aacaggaaac tgtacatctt acagaagcaa tgatgaactc tggagacatg ataaacctat
    47761 ctgagataga tggaataaag gtagataagc atagtactgg tggtgttgga gataagacta
    47821 ccatagctct tatacctttg gttgcttcat gtggagcacc agttgcaaag atgtcaggta
    47881 gaggtcttgg tcatactggt ggtactattg ataaattgga gtctatacca ggtttttcga
    47941 cagaaatgga gataagtaaa tttattgatt ctgtaaataa gtctaaaata gcagtttgtg
    48001 gtcaaagtgc aaaggtagca attgcagata agaaaatata tgctcttaga gatgttacag
    48061 caactgttga taatatatca ttgatatcat caagtgtaat gtctaagaag ttagcttcag
    48121 gagctgatgc aattgtgcta gatgtaaaaa ctggtgatgg agcatttatg aagacattag
    48181 aagagtcttt tgagttagct aaatctatgg ttgatatagg tactggtatg aatagagata
    48241 caatagggat tgtaacagat atggatgaac ctttaggttt tgcagtggga aactctttag
    48301 aagttataga agcaattgag acattaaaag gaaatggacc taaagacctt gttgagctat
    48361 gcgaagtatt aggagcatat atgttggttt tatcaaaggt agcacatgat tttgaagatg
    48421 gtgttgaaaa aataagagaa tcaataaaat ctggtactgc tatacaaaaa ctcaaagagt
    48481 ttatagagaa tcaaggtggt aataaagatg tagtagatga ttattcttta ttcaaaaaat
    48541 caaagtataa atatccagtt aaatcaacta aatcaggtta tataagcaaa attaaagctg
    48601 aagatgttgg tgtatcggct atgattcttg gagcaggtag agaaactaaa gatgatattt
    48661 tagatttatc agcagggata attttagaaa agaaagtagg agattatgta aatgaaggtg
    48721 aagttttagc ttacatgtat tataatgatg aacaaaagct ttcattggca aagggaagat
    48781 ttattgattc ctactctatt gtagattcaa aaatagaaaa aaataaatta atatatggta
    48841 ttgtaactaa agaagagatt aaaaagtttt agaaaatttt agaaaagtga ttataaaagg
    48901 cctaacatgt caaaaataat gttaggtttt ttattttttg atagactata aattatacca
    48961 aaaatatata ttttaaaaca ttttttacaa tataaataag tttattctac aagatgattg
    49021 aaaattaaag tatctagttt tataatagaa aatggataaa tatacataag gagtagatta
    49081 tattatgaac tttaaagaaa atagattgaa aatagcagta ttaataattg ttattttgat
    49141 tatcttagca ggtatatttg tgtttataca aataggtcct tatgataaaa ataacaaaaa
    49201 agatgtaatt atcgacgttc caagtggagc atctgttgga aaaatatctg acatattata
    49261 tgaaaataaa ttaataaaga atgaactatt atttaaactt ttggtaaagg ttagcaataa
    49321 agctccgtct ataaaatcag gaacatactt acttaatcaa tcgtattcaa acaatgatat
    49381 aataagtctt ttagtttcag gtaaaatata tcaggatggt ataaaagtga ctattccaga
    49441 gggagctaca tctaaagaaa ttatagcaat gttagtaagt aaaaatttag gagataaagc
    49501 tacttttgaa aatttaataa aaaaacctca agaattttat gataaatttc catatttgaa
    49561 ggaagatgga ataacctctt tagaagggtt cttgtatcca gaaacttatt attttaattc
    49621 aaagaaacaa tcagaagaag atattttaag cgaaatgtta aaagtatttg acagtaaata
    49681 cacggacaag tttaaaaaga aacaaaaaga attaaatatg actcttcaag aagtaatgga
    49741 aatggcatca ataattgaga aagaagctgt tcttgacaaa gacagaccta taatagcaag
    49801 tgtgttttat aatagactta aggtaggtat gcctcttcaa tcagatgcta caatacaata
    49861 tatatttgaa gagagaaaga aaattgtaac atatgatgat ttaaaaattg attcaccata
    49921 taatagttat aaaaataagg gattacctcc tacaccaata tcaaatcctg gtataaaatc
    49981 tattgaagca gcattatatc cagagaaaac agactattta tattttgtag ctaagattga
    50041 tggtggaaat aattatagta caaactatca agaccattta aaatacgtta aagaatataa
    50101 agaagcaagg gataaacaat caaaagatac aaaagcaaca aataaagaaa atacaaaaaa
    50161 ataaaccatg attataaaaa gtctaacagg gtaagaataa tgttgggctt ttttattgaa
    50221 aattgttatt cttagattta taataaagaa agtgtaaata tatataacaa tatgaattta
    50281 aaaaataata aattaatata aaacttgaat atttattatt ttagggagtg tttttatgag
    50341 taatatagtt aatgatttgg ttgaagatta tataagagtg acattaaaag aaaaagaagg
    50401 atttttaaaa gatttagaaa tttatgcaga ggaaaatagt gttcctataa tacataaaga
    50461 agtttcagat ttattaaaag tcttgttaaa ggttcaaaaa ccaaagagaa ttttagaagt
    50521 aggatgtgca attggttatt cttctatttt ttttgcaact attataggaa aagatgcaga
    50581 tataataact gttgagagaa atgaaaaaat gatagaaaaa gcaaaagaaa acataaaatt
    50641 agctggattt gacaataaca taactatact agaaggagat gcagaagaaa aacttagtca
    50701 agtccaaggt gaatttgacc ttatatttat agatgcagcc aaaggtcaat ataagctatt
    50761 ttttgattta gttatagata aattaaaaga tgggggactt ttagtatctg ataatatttt
    50821 gtataaaggt atggttgctc atgatgattt tgttgtaaga agaaaaaaga ctatagttaa
    50881 aagaatgaga aattatttag attatatatg taattgtgac tatttaagca catcattggt
    50941 accaataggt gatggtgtag cactaagtta taaagaaagt aaaagaggtg atgtagatgg
    51001 aattaaataa agtagaactt ttagctccag ctggtgattt ggagagattg aaaatagcta
    51061 taacatatgg agcagatgcc gtttatatag gtggagaaat ttttggaatg aggtctgcag
    51121 cgaagaattt tagtaaggaa gatatggcag agggagtagc ttttgcacat gaaagaggca
    51181 agaaagtatt cgtaacagta aatataatac ctcataatga agattttcta caattagaag
    51241 actatttgtt ggaactagaa gagataggaa tagatgcagt tataatagct gacccaggag
    51301 tgcttagtgt cattaaaaaa gtaattccga atatggaaat acatttaagt acacaagcaa
    51361 atacaaccaa ttatctaagt gcaaacttct ggtacgagca tggaataaaa agagttgtag
    51421 tggcaagaga attatctttt gatgaaatat ctgagataag agcaaaaaca cctttagata
    51481 tggatataga agcgtttatg catggtgcta tgtgtatttc ttattctggc agatgtttaa
    51541 taagcaacta tatgactgga agagatgcaa acaaaggttc ttgtgctcaa tcttgtagat
    51601 ggcaatatca tttggtggaa gaaaaaagac ctggtgagta ttttccaata tacgaagatg
    51661 aaaggggtac attcttcttt aactcaaaag atttatgtat gatagagtat ataccagagt
    51721 taatcaaatc tggtataaca agtttaaaaa tagaaggtag aatgaagact gcatactatg
    51781 tagctactgt tgtaagagca tacagaatgg caatagatga attttacaga gacccagaaa
    51841 actggaagtt caatccaatg tggatggaag aactaaaaaa aggtagtcat agacatttta
    51901 catcaggttt ttacttgaat aaaccaacaa cagaagacca aaattatcaa tcagcatcat
    51961 atgttagaaa ctatgatttt ataggtatag ttagagaaac agaagatgaa gatggtctta
    52021 ttgttgttga gcaaagaaat aaaatgtgtg ttggtgatga aatagaagtt atgggaccat
    52081 ataaagaaac tatgtttact aaaattgaag aaatgtacaa tgaagaagga gaagctatag
    52141 aatcagctcc tcatcctaga caaatagtga agttaaagct atcagtaaaa gttggtaaag
    52201 attatatgct tagaaaagtt atagaagaaa aggttgaaga ataataaaaa attgataaaa
    52261 atagtattag ccccttagaa attgtcaata atgaaattat ctaaggggtg atttcatgtc
    52321 aaaaaagaag actccatttt tgaaaaaagt gggaaagaga agctggtgta tatttactat
    52381 aattttaata atttatagtg ttttaattta taggctagtt gatatacaag tattaaaagg
    52441 tgataaatac aaacaaagtg ttgaatcaca aagcgttgag aaagtcgagt taaatagtgg
    52501 aagaggaata atctatgata gaaacaacaa gaagcttaca gatacaagta aatctcaggt
    52561 attaattgtt gaaaaagaaa aattaaataa taactataaa attttggagc ttattaagaa
    52621 agctactaag atgaatgatt tagatatata taaagctgta caagagcaat tgacacgccc
    52681 tataatacag attcagacta aaaatatcga taagagtatg aaaaaagaac ttgagaaaaa
    52741 tggaataatg gtagaagaaa aaactatgag gtacgcaaaa gatggtttat tatcacatac
    52801 aataggatat ataaaagaag atgataaatc aggtcaatca ggaattgaaa agagtatgga
    52861 tagtgtactt agaaattcaa atgaaaagta tataagtgct tttaaagctg gagatgcagg
    52921 aaatgaaaaa tctctaaaca tactaaaggg aagtgtaaaa actgttgata ataaggataa
    52981 agatagacat ctaaaaacta ctattgatta taacattcaa aaaaaattag aacaaatact
    53041 aaataaagaa gaaaatccta cagcagcaat aatctcggaa gcatctacag gtgaaattct
    53101 tgcaatgtgc tctagaccta attttgacca aaatgacata tcaaaaagtt taaaaggaaa
    53161 aaatggagaa tttgaaaata gagttataaa agcgacatat ccaccagggt ctgtatttaa
    53221 gatggtagtt ttattttctg cacttgaaaa tggtgttata gatgagaact atacttacaa
    53281 ctgtacaggt aagactaaag ttgggaatac taatgaaata ctgcgatgta ataaaagaga
    53341 tggtcatggt ttccaaaact taagacaagc tttttctaat tcatgcaatc ctgcattttt
    53401 agatatagct atgaaacttg gaaaagaaaa gatactcaaa tctgctgaaa aattacattt
    53461 atttgaaaag gttgatattg gtcttgatga agaaaaaatt agagaagctc caaaaaacat
    53521 atcaataaga aatttagcta taggtcaaga aaatatagaa tttacaccac ttcaaataaa
    53581 tcaaatgact caaataatag ctaataatgg aacattcaaa ccactatact tatataaaag
    53641 tcttgtggac aataatatga atacaataaa aacttataag tcttcaaaaa aagaagaact
    53701 tatttctcct tatgtgtgta cacaagttaa agaatatatg aagtctgtat ctaggattgg
    53761 tacagctaaa gacctaaaag atattgaagg tggttgtgga gttaaaactg gtacagctca
    53821 aagtagttta aataaaaaag ctatagacca tggatggata acaggatttt atcctgaaga
    53881 aagacctaag tatgtaataa ctgtgttagt agaaggaact caaaaaggaa ataaatctgc
    53941 aacacctata tttaaggaaa tatgtgaaag tataaaataa attatgtact ataaaattta
    54001 aggatatatc gtaactttga ttttagatag aaaattttgt ctaatgatgt acgatatatc
    54061 cttttaaaat atagtattaa ctttcttgaa caagctcttt ttctagtttt ttaagagctt
    54121 ttttttcgat tctagataca tatgaccttg atatatcgag tttttgtgca atttctcttt
    54181 gtgtcttata gccataagga gttaacccat atcttaactg gacaatttct ctttctctag
    54241 gagtaagaat tttgtttagt tgttcgtaaa gttttccaac ttgaactttt agttcaactt
    54301 catcaagaac atagttagcc tctgtaccaa gtatatctaa aagacttatt tcattacaca
    54361 ctactcttta tatgttattg gtattactgg tcttcatgta atttcaaatg gaccattaat
    54421 tcaaaagaat ctagtttttg ttctttagac ttataataaa ctgctttatc aattacagat
    54481 tttaggagtt tattttttcc aagggaatct gaatcatggt aaagtgataa cacagtttta
    54541 atatcttcta ttattttaga attgtctttt ttaacagtac ttaatctatt ttttactgtc
    54601 ttaattgaat ctttaatttc ttcagttctt gaacttatat tgttggacct ttcaataaat
    54661 gtatcttcat catatattcc tcgttctagt aaatcatata acttattttt ttgcttgcct
    54721 aattctttta attcagtttc taagcccttt aagactcgtt tttgaaattc tatattacta
    54781 tctttattat ttttatctaa gtctatatca gatgctttta attgatattt ttttacagtg
    54841 tcttctaaag attttaaaat ggcagcttca ataaattcaa atcgagaact tttattgcaa
    54901 ccaggatgat aacaaattat atagtcgtgg tctgcatatg gtctatatac taatggtcta
    54961 ccacaatttt tgcaaatcac tattcctgca agtggatttt ttatttgatt accatagctg
    55021 acatgaccat tttttttgag tatattttga gcttttttcc atgttatttc acttattaaa
    55081 ggttcatgct ttccttttgc ctcaatccat tcatctttag gtcttagttt aactgttttt
    55141 attttatttg gatttttaga ttttttgtag tccttttttt gccactgaat gtagccacaa
    55201 tataccttat tttttattat atttgtaatt gcagaattgt accaattagc acctgtagca
    55261 gttttaatgc ctaagttatt taggtatttt gatattttac tacaacccat atcttcatta
    55321 atatataagt caaagatagt cctaactaca tcagcatcct tatttggtac aagtattctt
    55381 tcttttctac cagttgttac agcatcatat ccaaatggag cagaggttcc tatgaaattc
    55441 ccttcttcaa ctgattttat tctacctctt tgcatccttc ttgatataag ttttaattct
    55501 tttcttgcca taaatgcttc aaattctgaa tactcctcat caaattcatc tgttaggtcg
    55561 tatgtttttc taggtgtgat aattttggtc ttactttctt tgaatgtttc taatatgata
    55621 ccttggtctt tcatgtctcc acgaccaagt ctgtctaagt ccattactaa gactgcatca
    55681 tatttatttt cttcaacttc ttttagaagt tcaagcattt tgggtctatg tattatactt
    55741 tcaccagaaa ctaattcttc ttttatctca attacatcta agttttgttc ttttgctagt
    55801 tttagtaggg ttgatttatg tctacttaaa gtttcaaatt cgccttgttt ttctgcctct
    55861 tcatcagcac gggattttct taagtatatg gcaacactca taataagtaa tcacactcct
    55921 tatgcactat tatatagtaa atcaatagag tttaaaatat agaaaataag catgtcaaaa
    55981 gttaatttaa ctttcaacat acttattttc tataatatta atgccttata atcctttaat
    56041 atcatttaga ttagtttttg catattcatt atccgggtta agttcaagcg ccttattgta
    56101 agattctcta gctttattaa attctgattt actcataaaa ataacacctc ttaaattgta
    56161 agcatcacta gcgtctattt tataagcttc attattttta tctagatatt ctaagtattt
    56221 atcaattgac tttaaagcct catcatatcg ttgtaactct atataaatat atgattgtgt
    56281 ataatatgca agtggatttt tatcatcaat ttctatagct tttttgatat caatagcagc
    56341 tttattataa tccttatctt catctttttc tgtttctgac ctagcgattt tgacataatt
    56401 agagctaaga gctcttttaa agtctttatg ccataataat ttatattcat tatcttcgat
    56461 tataaaatat ctatcaaaat ttgcagtatc ttctttattt tcagtgatat actttatagt
    56521 atcagtttct tttattttaa caagatttgt gtactcttta ttagaatatt tgtatttctc
    56581 tactttattt tcttcaccaa gtttataatc ttttagggtt tgaagtttaa ataaagtatc
    56641 ttgatattct tcaaattttt ctagactgac gctttcctta ctgtctttac ttaataaatt
    56701 atatgctact tcgtagtctt tgatttttat actatcaagg tactttttag ctacttctgt
    56761 agcactttct tttggagcac atccaaccat tgatatcata attaaaaatg atactaatat
    56821 tgctgttatt tttttactga ttatcataat ataatccccc ttatattgtc tctcattaat
    56881 tttattttat caccatattc taccaaagtc attaatttag gagtgatatt tttcattaat
    56941 attatattaa gtaataataa ctttttaaat ttatggtaac attttcctga aaagtattat
    57001 ataatttagg tgaaaatatt taagagaagg agatattatg aaaattaaaa aattattaac
    57061 aatagggtta tctttatcta tatttattgc tagttgccct atatctgcaa atgctcttga
    57121 taaaattgaa tcaattaaag gtgcagataa atacgaaact gctggtataa ttgcagacaa
    57181 acaaaactat actacagcta tattaattaa tgcagacagt acaatgtctg atggattaag
    57241 tgcaagtgga cttgcaggag ctataaacgc tccaattctt ttgactaaga aaaataacat
    57301 accaaatgct acacttaaaa gattagaaaa ggcaaaaaaa gtatatataa ttggaggaga
    57361 aaactctatt gataaatata ctgaaactgt tctaaaaggc aaaggaatag agattaaaag
    57421 acttcaaggt agtgatagaa ttaagacaag ctataatgtc gcaaaagaaa taaactcaat
    57481 taacaaagta aataaagtca tattgactaa tgcatttaaa ggagagcctg atgcaatgag
    57541 tgttgcacct gtagcagtta gagataaagc agctatagta ttaactgatg gaaaaagtgt
    57601 tccatttaat acaactggtg tagaaagtta tgtaataggt ggtacttcat caatgaatga
    57661 caaaatagtt aaggatacta attcaactag attaggtggg acagatagat atgatactaa
    57721 caaaaagata ataaataaat tttatagtgg agtaaaagaa ttttatatag caagtggtac
    57781 tgatttagtg tatgctcttg ttggttctac tgctgctaaa aataatgcta ttgtgttagt
    57841 tgataatgat agtaataaaa gtgtattgaa aagtacaact aaattaactg ctataggaaa
    57901 tttgagtgat agtatattac agcagtgttt aaatgtaaca aaaaatatag gcgattctaa
    57961 tactggaaga gaatatacag tagaagatgc tgctaatgca gtgaaaaaac tattaggtgt
    58021 gaagaaattt tattacaaac ctaattattc agaagatgaa gatttaatat ttctactaga
    58081 taaaaatttt gatttttcag gaaaagagta ctatgtattt gcttacatta aacagggtgc
    58141 agagggtgat gttagatact gtgtagctaa aaatgatatg agcaaagttt atacatatga
    58201 tgttaatggt aatatgaaag tatgtaatcc agatgattat aaaaataaag gaagtataac
    58261 agaggaacaa gcaaaacaga tagcattgaa agaatgtgct aagagacata aagtcagtat
    58321 caataactta gtagttgata tgatagattt tagagatgat atatatagtg gaaatgtcta
    58381 tgctgttaaa atcaattcaa aaaatagtaa tggtactttt ggttggtttt ttatagatat
    58441 agaaactggg aaagtttata attaaaatta gaacttttaa acaagtgttt ttaattatat
    58501 aatttaccat aatatgttat aatattttta gcaagaagat ttaacttaca atctatagag
    58561 tggagttcat gtacaaaaga ttatcctccc aacgattcga agggaggtga gttcatggat
    58621 aactttttgt ttaatgtttt agctagttta acagctagtg tggtagttta cttaatcagt
    58681 aaactattca aaaaagcaaa aagccactct cgcacaaaga gtgacttacg agttgaattt
    58741 aaatttatat ttaaatccaa aaaataaact ctgtttatga tgaactccac tctaacgcaa
    58801 aatagattgt agttcttctt gcttttatta taccacaaaa cattataaat aaaactgttg
    58861 tttataaaaa aatgcaaagt aaaatttttt ataaacaatg ataaaaattt tattatagag
    58921 ctattaactt attaaatatc tgtaaatgag cagatatttc ataagttaat atttattgtt
    58981 tacataaaat atttggtaaa aataagtaag ttttatatgt tataatagtt gtagcaagaa
    59041 taataatcga aagcagcaag catgtcagct ggtgttatat cagtttatat ttatgataaa
    59101 ataaaaatct cccaaacgcc aataagaatg attcaaaaaa ataatatttt cacttaaaaa
    59161 taatcactct ttataggagt aaattatttt cttgatttta ttatactaca aattggtaca
    59221 gatatttaaa aataatatat tcataatatt ataaatagtt ttgcagtgag cgatattttt
    59281 gataaaatag ggcttaacag ttgaaacata aggcattgag ggtatatgat aaatattatc
    59341 atttgcacta ctcgtggttc actgcaaatt tgagagaatt gtatagatgt aagtcttgga
    59401 aatgctcaat ttattttggg gttttatatt aactaagtgg tatgtaaagt gttcccctct
    59461 aagctctgta tatatatatt ccgtttgttt tatattaact aagtggtatg taaagaagtg
    59521 ttgatattta tattgtctat ccccgctagc ttgttttata ttaactaagt ggtatgtaaa
    59581 gtcgtaaatt acgaccgtac ctttcgtaaa ataacaatcg ttttatatta actaagtggt
    59641 atgtaaagct ttttgagtat gagtacaagc ataggaaaat taatagtttt atattaacta
    59701 agtggtatgt aaagaacaaa aaagatacat ctgtaactaa tttttatact gttttatatc
    59761 aattaagtgg tatgtaaaga cagatataat atcaaaataa ggttaggact tttaaaagca
    59821 tagccatatc agtaaaaatt taattatcat ttaaaaaata aatttttatt taaagaatac
    59881 acataaatat ttccagactc aactctctta aactattttc atatctttta gtagatacct
    59941 ttgttgtttt ttaatcttta gcaacttgtt cttgagtgaa cctcttattt tttctaagtt
    60001 atttcaagct tttcaaaaaa ttctctattt atattcatca cacatataat acaattaatt
    60061 cagctttaat tgccaatatt tagtttttct gtatctgata aaccaagaat ataatcagta
    60121 tataaaccaa aaattttagc aaatattatt aacccatcgt ctcttgttgg tctttcacca
    60181 gactctattc tattcataac acttgtattt atatttgttt tttcaagcaa ttctttttga
    60241 gaactattca tattttccct aatatattta atcctttgat ttacatccat acataattat
    60301 ctcgaaaagt ttctgttttg gaaatattgt tattgaaata tagcaattaa tgtgaatata
    60361 tgaaaaagat acactatgat tttataaaaa agaagacata cataaaattt atacttacaa
    60421 agtgttgcaa atgagttagg ttttaaaaat gcatcaattt attttaagta caggaaaggg
    60481 gaatattcaa ttagagttga tatgttacct ataaactatc taagatactt gattatgata
    60541 tagaaaattt ttttacaaat taaatttcta agatagaaat ttaattaaga ggatgatgag
    60601 gatgaataat ttacaagtaa tataaagaaa taataagaga attttaaatg catagcaact
    60661 agcagatata tatgaaaatg atgtaaacaa tatataaact aacttcaata gaaataaaga
    60721 gaatgtaaat tatgttttat tacaattcga gtatttgaaa gaatttaaga actaatctat
    60781 taatagtcag ttgatttcaa aacattctag tcaattatac ctttggatcg aaagatgtgc
    60841 aaatagacac tgcaaaatat tagatattga taaaacttgg gaacaatttg acaatttaga
    60901 gaaaatatat ttcaagatta agcgagagaa actaagctgt atagaagatg tattaataga
    60961 aaatttaaga tttaaggata caaattaata aagcaataat atggcattag atgtaaaaat
    61021 agaagttaaa ataataaaag atgttgttat attaaatata acacattgga aaaaagaaac
    61081 aagtctatta acagttaaaa tagctagaag tcaaggtgat ttaagttatg taaaatattt
    61141 tgctaatgag agctaagagc ttcttaacaa gagttttggt gtgtctcttg aaacaaggtt
    61201 aacaattaat aaaagacgaa tggcagaaga aggcgtatgt aagtttaaaa gagataagtt
    61261 aaacaaacta gatactatgt aagaggataa gaaacttata gaagaatatg ttacttttgt
    61321 aaaggattta gctttaaaat atagaatata aagtgatttt aagtaaaaat tgtaacaatt
    61381 aaataagtat aagacaagtt tatgagttca tattttataa caaggggtga tgttatgaaa
    61441 atactacaac aatttaaacc atacaaatat gataaagaaa aaaatataga atatgatgaa
    61501 aaaattatag ctaatcaaaa cacagaagtt tatatagtat atccacgtat atctgatgaa
    61561 gaaaatagga gaagatggga agagttcaat gaagtagcta aagaagtagc tattaatata
    61621 gctatgaaga aagttgagac agtagaaagt taagagaata gagaagttgc taatacttag
    61681 cactttctca tagaagaaaa ttggacaact atttttaaat aattaggaat aaaaaagtta
    61741 aatcatattt gaaaaaaggc gataaaattg ttgagtattg ttattagtaa taagaatata
    61801 ttaactatgt attaaaagaa attataagtt tttagtaaat atagtattta aggatattaa
    61861 aactggtaaa aaatatcatt tagactatta aataaaaaag tgctggtcaa agtagcaaca
    61921 caataaataa aaaaacttat agaaattata agataaaaag atgagatttg aaatggtcga
    61981 agttaatata aaaattaaag gtgaagtaag tgaaataatt aactcaatta gaggtatatt
    62041 taatagcttt gatgaagaat taatattaga tataaaatca gagtaagaat ataaaggtag
    62101 atacgtagaa agttataagt aattcaagac ttaaattaat ttctagtttt tttaatgcaa
    62161 aaatttaata aatttcaaaa tataataatt ctgacatcta aaaagagcta ttaaaaatga
    62221 ataatattga ctattaagat atgaatagtg tacatatatt aaattaagat atcaagtagg
    62281 ttaattttat ataatgatgg ggctcaaatt gaagaggcga tataaaaatg tattaatata
    62341 tataaatata agaactataa tacatattaa ctgtaaaatt aagtttatag agttatattt
    62401 aacatttaat gaactgaaaa ataaattagc aaataatgaa aaaacaacag taataaatga
    62461 gaataacaaa gtattttcag gattagtgga tttttctaat tgagctttaa tcctagtttg
    62521 ttcaatttcg atatttctaa tattatcaat ttatttgtaa taattatcaa tttttgcgaa
    62581 atatttttga taatttatag aactttatat attttccttg aagtattttt cgcccttatt
    62641 gtttggtttc caattttaaa actcataaac tcccaataaa ttcatgtata atatacctta
    62701 atttataata tatttaagag tttatttcag taatttttcg aacgattttg atatatttca
    62761 tttatagttt tcaaaaactt atacaaaaaa gagtgtttca tctttctaaa cactcttttt
    62821 ataagaattt gaataataat tttttaaaaa ttgataatat ggttatttct ttttcaagtt
    62881 tatagtttcc tcatttccat tccaagatat aattagcttg taactagatt ctctatttga
    62941 ataaagacct ggtctttgta tttttattgc tttttcttga cctgcttcta aaatttcatt
    63001 ttttacaact acaactgcat cttcaccatc tataaattga taggaataat taaatttttg
    63061 ttcaactaca tctttactat ttttatattt tatttctaat tttgagtgtc cttcagtagt
    63121 tacaaattta gctttccaat tttctgattc tccaataaag acatttttat cattttttat
    63181 attaagtata gctatcacag agattattaa aactataaga atacctataa aaaatttttt
    63241 cctcatatca atccctcctt tgaataatta taacatgaga atagttattc aatactaatt
    63301 ttaaaaatat tgtggattta tattctatta caatagaatg tctgttataa caaataaaaa
    63361 gtaaggatta atatgaatta taggttaaaa aaatctgtaa caactatttt atctttactc
    63421 ataatgacaa tactattacc aacaaatgca agtgctagta aggtagaaga ttcatctatg
    63481 aaagtaatgt attcagagaa acaagtaaca gacatggaca aattatacga tatggctaaa
    63541 aatggaatta ctgatgttaa aagttccaat gaaaaaggta taatcaaaaa tgcaagaaca
    63601 ggagagtcca tatacgttga ttctatatca acaactcaat tattagaagt taaacaatct
    63661 aaaaatttaa catcaaagat atattctaag acagtttttt tgatactaat acaataaagc
    63721 ctcttagaaa agcaagtata tcagaagatg gatgggataa aactggtggt gtaaaagcat
    63781 ctggtacagt tacatataca atatcaaaag gagatggagc atttcaatat atttccgtta
    63841 gtaaagtttc tggaaactgg tctattgcag acggccagat tcgtgtaaca aatagaaggg
    63901 tgcatataaa tcaaactgga tttatttcta atgagctagg aattaagcag caacaaaaga
    63961 aagagccaac atcaaattct ttctcatata atgcaccttc tagttggaaa ccagtaggta
    64021 gagattcagt tcaatacaat tgtgggtttg aattaattgc aacattagta agaggaggaa
    64081 gttcttgggc attcaatttc attgttcaac cttaaaatat tttaagtgaa ttttattaaa
    64141 atcaaagata tacatatact ttaaaattag agaatgtaaa ttaatttgtg tttttaaaga
    64201 taattcctat gttatagtaa caattgctta tttactatta atatttctta atatatgaa
//
LOCUS       DAMKNB010000014        61649 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.014, whole genome shotgun sequence.
ACCESSION   DAMKNB010000014 DAMKNB010000000
VERSION     DAMKNB010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 61649)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 61649)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..61649
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.014"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            complement(597..2381)
                     /locus_tag="PC494_001041"
                     /pseudo
     CDS             complement(597..2381)
                     /locus_tag="PC494_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860844.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding repeat-containing protein"
     gene            complement(3165..3353)
                     /locus_tag="PC494_001042"
     CDS             complement(3165..3353)
                     /locus_tag="PC494_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3911562.1"
                     /translation="MNNKKKAFLISGAINVISLIIVFSLFHYNIIENSTQNMIITVIL
                     IFIFEMIKIKIIEKYYKL"
     gene            complement(3379..4518)
                     /locus_tag="PC494_001043"
     CDS             complement(3379..4518)
                     /locus_tag="PC494_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic family protein"
                     /protein_id="HDF3911563.1"
                     /translation="MVIKLTIEEYKNKYFTGNKIVLSLNSFDNKELYYHETENILNLI
                     NEIDKLTSSKIFKTIEDKNDLALESYYSSVIEGAFSTRKIAKSIIRGKMKPSNKSEYM
                     IYNNHRALEYGLDNLDKLYSHKFIYDLHHILGENCLDSEEYEYRTEKVYVCDSKGEII
                     HIGLEPLKIYDFMSKLIDFMENSKVSNLIKSAIIHFYFVYVHPFSDGNGRTSRALSYL
                     YLIDKGYDTFKEFSISYMISKNRTKYYKAILDVENKGNNLTVFIEFMLKSIIQSINEM
                     RNMHDRKSLESILKEELFENDITLSATEEHILKYICNKDNYSMTLENYIKKNKSRYLK
                     AGIKEIELVDQLMEVFSNLEEIEILSKEKNIYKVNDKYLKMLDID"
     gene            complement(5050..5889)
                     /locus_tag="PC494_001044"
     CDS             complement(5050..5889)
                     /locus_tag="PC494_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HDF3911564.1"
                     /translation="MSDIKNEVSKKTLSKKDVIKSWLRWFFFAQSNYNYERLQSTAFS
                     HSMLPVLKKLYPDKEELKQEVETHLAFFNTEPICGCVIHGITIAMEEEKANGADEISG
                     DGMNAIKTGLMGPLAGIGDTLTQGVITPIVLAVCIGLTEGGASIAGPILFVIAQYIIM
                     TSISFGMWTNGYKYGKKAVESILQGGIVNKVIEGASILGTLVMGGLVGRFINLSTPIS
                     YTSGDFKFSLQTDLLDKIFPGLIPLVLTLLVLFALKKGLSPIKIMFILIVVGAITGIL
                     GLF"
     gene            complement(5913..6671)
                     /locus_tag="PC494_001045"
     CDS             complement(5913..6671)
                     /locus_tag="PC494_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDF3911565.1"
                     /translation="MHISLIQAVLIAIFYYLSWSPWLTYVGFFTWNRPLLAGFVTGII
                     LGDPVQGAIIGAGINMIYLGFISAGGAQMGDPAFAGYVGTALAIASKLDVSTAMAIAV
                     PLGTVATVLWIGKMTVNSFFAHWADREVQKGNVDRVAFINIVPPQILLFAMSFIPALL
                     VVYFGPNAIDGMLEVMNDNVLHVFNVIGAMLPALGIAMNLKLIGNKFTMPFFILGILM
                     AVYFKVDIIVISVIGVILALTITSIKYGKDSATS"
     gene            complement(6718..7191)
                     /locus_tag="PC494_001046"
     CDS             complement(6718..7191)
                     /locus_tag="PC494_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDF3911566.1"
                     /translation="MSNIALTRIDDRLIHGQVITAWCKITSAKRIVIVDDLVVKDPFI
                     VQVLQMAAPSTVKVEVHDVESGAEVLKSYNGDENLIVLVKYPKTVLGLVNSGVDLKEL
                     NVGGMGAGLGRKSFYKNISVSDEEKEIFRELISKDIKCFIQIVPDAKKIDVGTLL"
     gene            complement(7220..7636)
                     /locus_tag="PC494_001047"
     CDS             complement(7220..7636)
                     /locus_tag="PC494_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDF3911567.1"
                     /translation="MIHMAGIIIATHGNMAKAMLESAELIVGKQENVETLGLNHGDSI
                     DEFSRKLEDGIEKYKDEGVLVLLDFYGGTPFNTSAIIINKFAKVCELECLTGVNLPML
                     LELFLNRDTMKLKDLKNLCEEVGISGIKDVKTVLKL"
     gene            complement(7683..8735)
                     /locus_tag="PC494_001048"
     CDS             complement(7683..8735)
                     /locus_tag="PC494_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HDF3911568.1"
                     /translation="MKSVRFYGIRDTRVEDVDVPKILEKDDVIIKVKVAGICGSDISK
                     YSKTGPHMVGEILGHEFSGEVAQVGKEVRSFKIGDRVAVCPAMPCFECNECKKGLYSR
                     CNNVAIIGNKELGGCFAEYTKVKERNLIKIPDEISYETAAALEPVCIAGHGLFRSEAK
                     VGDTVVVLGTGPIGLFSIQWAKIFGSTKVIAVDVFDEKLDLAKGLGADICINAKEKNI
                     VEEIKRLTDGDGADIVIESAGTPLTCGQVLLLAKKGGTVLYAGVPYGDVALTREQFEK
                     IVRSELTVKGTWFGNSFPFPGKEWSAGLYHMQKGDMNVEKLVTHRINLEEVPAYFEKV
                     YKRDIFFGKIMINIDN"
     gene            9131..9811
                     /locus_tag="PC494_001049"
     CDS             9131..9811
                     /locus_tag="PC494_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HDF3911569.1"
                     /translation="MKKVYQGKTKDVFELDNGNYLLKFKDDVTGKDGVFDPGENSVGL
                     SIDGIGRANLETSVKFFEILNNAGIKTHYVSANLEEATMEVLPAKVFGNGLEVICRYR
                     AVGSFLRRYGSCVEEGAKLDCYVEATLKDDDRCDPLITSEGLEALNIMTQAQFDSMKS
                     MTQKISNIVRDTIAEKGLELYDIKFEFGFYNDEVILIDEIASGNMRVYKDGVIVDPMD
                     LTALLLDK"
     gene            complement(9944..10264)
                     /gene="sugE"
                     /locus_tag="PC494_001050"
     CDS             complement(9944..10264)
                     /gene="sugE"
                     /locus_tag="PC494_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000118520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quaternary ammonium compound efflux SMR
                     transporter SugE"
                     /protein_id="HDF3911570.1"
                     /translation="MKWLFLFVAGLFEVFWAFQLKNSHGFSKLTPSILTVVGMIVSFY
                     FLSLALKHLPLGTSYAIWTGIGTVGTAIVGMAILNEPISISRIACIGFIVVGIVGLKL
                     LSTN"
     gene            10646..11473
                     /locus_tag="PC494_001051"
     CDS             10646..11473
                     /locus_tag="PC494_001051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon-nitrogen hydrolase family protein"
                     /protein_id="HDF3911571.1"
                     /translation="MNFYKIAVCQMITTENKIENINHAVDMVTEAAINGAKIVVLPEM
                     FNCPYENKYFPKFAEEYPGETTTILSKLAEKHGIYLVSGSIPELEDGKIYNTCYVFDK
                     NGDLIGKHRKMHLFDIEVTGKVSFKESDTLTAGNDVTVIDTEYGKVGIAICYDIRFPE
                     LSRLMALKGAEIVILPAAFNMTTGPAHWELSIRMRALDNQIFYVGAAPARNMNASYIA
                     FGNSRISDPWGRIIAQADEKECIIYADIDRDLIPDIRQQLPLLKHRRTDLYELNTLK"
     gene            12295..12969
                     /locus_tag="PC494_001052"
     CDS             12295..12969
                     /locus_tag="PC494_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF3911572.1"
                     /translation="MNNKILVVDDEEGIITLLKDYFEMNSYEVYTAQSGKDALKKISK
                     NPDIILLDINMPEIDGIEVCNRIRDYVSCPILFLTARIENTDKINGFRAGADDYIVKP
                     FDLDELGARVSAHLRREQRKSNQTKIKFYNDLTIDYEKRLICIYNNQISLSKKEFDIV
                     ELLSMNPGQVFDKEKIYDRVWGYNSNGNSDVIMEHIRKIRIKLSKHTLENYIETVWGV
                     GYKWIK"
     gene            12957..14117
                     /locus_tag="PC494_001053"
     CDS             12957..14117
                     /locus_tag="PC494_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HDF3911573.1"
                     /translation="MDKINNMSLKKAFFVLTLSSLIIASVLTTFAYILLNNLYNSIQD
                     KYLKTPINTGIITIVQNNVNQFSDYDKTLLNIINILQLVLPLIFFIGLLLLADIIFYK
                     VKLKTPIEILNKGAMEISNNNLDFCLEYNNNDELGNLCNAFEKMRSELNKNNIKMWTM
                     INDRKQLNAAFSHDLRNPLTVLKGYSNYLTKYIPTGKLSDEKILSTTQLMSDHINRIE
                     YYVENMSNAQRLEDLVVSKSMSNINKFIENLDENISIIAKQEGKSFTLKSQINNINLF
                     FDENIILRVVENIISNAFRYARNNVSILIYLEQELLTFVIEDDGIGFSKESLKLALRP
                     FYRDKTLNDSNAHFGMGLYISKILCEKHGGSISIENNSTNSAKITAKFSTRN"
     gene            14388..14861
                     /locus_tag="PC494_001054"
     CDS             14388..14861
                     /locus_tag="PC494_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="HDF3911574.1"
                     /translation="MLSSTFCSLPFWICYFWCGISDIFDGLIARKLRQQSGIGAKLDS
                     IADFIFSVTILVTVGKNIALPMYLWWCIVAIALLRLISYSIGFFKYRTFSSLHTLMNK
                     ITGISIFAFPLLYICFGLDVAGIMICIVAFLSSFEEIAIMIKSKELNRDIKSIFM"
     gene            15147..15815
                     /locus_tag="PC494_001055"
     CDS             15147..15815
                     /locus_tag="PC494_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF3911575.1"
                     /translation="MIIKAKQLSKIYGSNNNKVIALNNVNLEINSGEFVSVIGPSGSG
                     KSTLLHILSGLDNPTSGQVLLDDKDIYKHTEKELSALRRKSFGFVFQQFNLLPVLTAS
                     ENISMPVLLDKKQPDKEYLNEISSLLGIADRLNHLPHELSGGQQQRVAIARALIAKPD
                     IIFADEPTGNLDSKSGSEVMNLLIKTSKQFGKTLVVITHDDRIAKLADRKISIIDGVL
                     MEVK"
     gene            15818..18286
                     /locus_tag="PC494_001056"
     CDS             15818..18286
                     /locus_tag="PC494_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF3911576.1"
                     /translation="MKNYLSLSIKELKSQKLMTTFIIIAIVLSTIMTTVVGQSIGILQ
                     NLRIEQARSFNGDRHVSFHQLTKNQVDDIKKDDRVYQAGTSITLGSSKIKDSGISVLV
                     KEYDKTGLSNYPKLMKLKSGNLPKDKNEIALDENTLKLMGIKPRLGVTIPMNLDISLL
                     NDTIPPYNYTANFKLSGILEDDYTGYVSGIVNGIVGKGTSENLLPKRYILSSLDFKIK
                     QQEKFQEIVNQLAKKINLSHNSIQYNWIYLNALKIQFEKDENSSNSDGISMIILVSLF
                     VALLVLLASGLVIYNILKISVTKKIKEYGCLRAIGAEPNQIYKIVILQILILCTVAIP
                     IGAVIGIISSKGITGMVTNILNPDILLANDNKEITELIHKNTTAYMFPLVLSTNVSLI
                     FSFISALPSAIYASHVSPKIAMVGSTTKIKRKIKREKTIKNFERHLAWLNLKRNKGRT
                     IITILSLFMSITVFVALSEFSNVLDVSRSVSNLKEGDFSLTNEISGFDKSTLDKITKM
                     KNVNRTSFIKYSEYKQGEIDTDINFENSGEMLKIIGIDEQTLKDLMPSITDSILEDFK
                     NGSICFIKNPIAISTPGVKTRHTNLKPKDSITINKKQLDIYSTVDKMFFLQGNGWING
                     VDVIVYDSVYNTLTNKNKFNQINIYAKDKSKLEQIRLSIEQICENNPGSHWISYIESD
                     KQLKESFKQIEFLAWAVILFVGLIGTLNIINTTHTNINTRTNEIGVKRAIGMSNSSLY
                     KMFLWEGVYYGIFAAIFGSIAGYASAIIINMATIEKLDFTNIPITSILQATIISVLAC
                     IIATLIPLRKVKKMNIIDCIDINL"
     gene            complement(18526..19950)
                     /locus_tag="PC494_001057"
     CDS             complement(18526..19950)
                     /locus_tag="PC494_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF3911577.1"
                     /translation="MKNQSLITQFRHTFIFIIIASIVATVITYVFALYLYIHSLNKDI
                     YPPNYYERQVPRIEKYINEKNITLLSQSNEEGLKRTIRGDDMLYQVVDNNGNILYGTN
                     PKKLFKTKEELFNNFINKTVRKGGYIHTVPIKGDNGKIEGAVILFYQVKITFANIRGR
                     FVFAVIIMALFSPFLYIVGFTRWLSKRFVKNINQPLHLLIDASKKIKEKDLDFEIDYY
                     SDNELGKLCSAFSEMKDELKGSLSAQWKMEQERVEMVEALAHDLKSPLSIILGYTDAL
                     IGNNTDDNEKLHRYLTVIRENTEKSAALVQKMQYTSDLEKSNIQLNLVPINLPEFLRQ
                     KVQDYELQAHQKEVELILKMQGNIQSPIQIDVDRLTRIFDNIISNSLQYTPSGGNISI
                     TVKDEKNCISYEICDSGRGFSSKDLKKALDKFYRGDEARQTKGGHSGLGLYIVKQLVE
                     QLGGSVKIENSKSGGACVKFWHSI"
     gene            complement(19969..20661)
                     /locus_tag="PC494_001058"
     CDS             complement(19969..20661)
                     /locus_tag="PC494_001058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF3911578.1"
                     /translation="MSKILIIDDEMDLVMLLEDELKAKGHEVLIAYDGQAGIELSKQE
                     PDLIILDIMMPKMNGFEVCQAIRDDVLCPIIFLSAKQSETDKIKGLTFGGDDYVTKPF
                     GLRELMARIEANLRREKRSQYINEENKRSTLYFGKLCLYMKERAIKIDGKNIDLTKIE
                     YDIVELLALHAGQVFSREQIYEKVWGCDSEGDSSTVVERVKKIRAKFSAVTPEKEYIS
                     TVWGIGYKWNKM"
     gene            complement(20716..21492)
                     /locus_tag="PC494_001059"
     CDS             complement(20716..21492)
                     /locus_tag="PC494_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic immunity ABC transporter MutG family
                     permease subunit"
                     /protein_id="HDF3911579.1"
                     /translation="MIKLLSSEWLRAKRTAVQWLTLCMPIIFSLCVVFYLTTKSGSTQ
                     EFAFEGFFTVWTVFIIPIGVGILAGFIVQEEELAGNFNGFLCVGISRVRLYLGKFLFL
                     LFCLTICTFIATLILCIGMSIAVPSGATIWLFLSAAGLVVIGTLPLLAIHLWVSFAWG
                     MGASIGISIGGILMAAILGLTSVGEKVWAFVPWTWPVKLGMLPGIYFIKEAGTISTEA
                     FYSKVMQTASIELIVVAIGLIIFLIGGVIWFKMWEGRKSY"
     gene            complement(21489..22259)
                     /locus_tag="PC494_001060"
     CDS             complement(21489..22259)
                     /locus_tag="PC494_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic immunity ABC transporter MutE/EpiE
                     family permease subunit"
                     /protein_id="HDF3911580.1"
                     /translation="MNALQSELLKYKRTFMGKLIVFFPVSFAAYAFIMQSTLMQNPLS
                     QTTSWAWQNLLALIFNWWSFLFLPIGFALFATLVAFQEKKAGNYRALRTHNVSPMTLW
                     INKVIAMAVYSFISTLVLIVVTIITGLILKAGPVPFGQIIGASIVCWVVSLAILPLQL
                     WLATWKGMFLSMGVGALGMIFGVLAATKPFWIAVPWSWAVRMVCPIINIHPNGTILEA
                     GDPLLNTSVIPIGIVVSLVVFIVLTALTAAWFNRRDDK"
     gene            complement(22256..22960)
                     /locus_tag="PC494_001061"
     CDS             complement(22256..22960)
                     /locus_tag="PC494_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014466355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic protection ABC transporter
                     ATP-binding protein"
                     /protein_id="HDF3911581.1"
                     /translation="MKDLILETKNLSKRYGEQMAVNNVSLQIERNSIYGLLGPNGAGK
                     STTLKMLVGLLRPTNGRIIFDRKPWKRESLAKIGSLIESPALYGNLTAEENLLVHTKI
                     LGIPKDKIYEVLEIVNLKNTGKKRASQFSMGMKQRLGIAIALLSDPELLILDEPTNGL
                     DPFGIQELRELIASFPKKGITVILSSHILSEVAQVVDNIGIINGGRLLFQGMPDPNEN
                     LEEFFTDVILKGGQNR"
     gene            complement(23215..23727)
                     /locus_tag="PC494_001062"
     CDS             complement(23215..23727)
                     /locus_tag="PC494_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3911582.1"
                     /translation="MKKISQEKISTHIQEIPQEKIEQWKSLYEKYKSILKVNSKSVLE
                     IIEFLKRKYVIVEETSEEFKHVVINNIKLNKPFSQKISSDKELKPIVFTIPNEGNAKK
                     LYDTQEEIYSGCKIIVGMEFETGCVFVEGSDELNDEITSFKGLDKYDINNYYLVANYI
                     RCLKKYKLID"
     gene            24053..24310
                     /locus_tag="PC494_001063"
     CDS             24053..24310
                     /locus_tag="PC494_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3911583.1"
                     /translation="MILNRAELFRGYSLNRFNEICNILSVNKIKYKYKVKNNAYSKKP
                     FFNEITLGNLGQKEDFSYEYLIYVHKDDYEQAESLINSKLR"
     gene            24453..25079
                     /locus_tag="PC494_001064"
     CDS             24453..25079
                     /locus_tag="PC494_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase family protein"
                     /protein_id="HDF3911584.1"
                     /translation="MKINIKSKLSEFIKQNNLFDDSRIISYLPNITIETDKIKTIMIN
                     EVVPTNTNDDFYSVDKDADYLKTTIPLFDSAGIKVSNINDILDMGIYITNAVKLPKSE
                     YTITRDTIKLHMPILEEEIKLFKNLEVVMLMGDVAKKSFNMITKKHIKKNVIPSISTY
                     KLRNNELYYDNLRVFPSYIMTGGNILIEKSKFEMASEDIKKMFEIING"
     gene            complement(25326..26105)
                     /locus_tag="PC494_001065"
     CDS             complement(25326..26105)
                     /locus_tag="PC494_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901940.1"
                     /note="N-terminal region resembles flavodoxins. C-terminal
                     ferrodoxin region binds two 4Fe-4S clusters; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EFR1 family ferrodoxin"
                     /protein_id="HDF3911585.1"
                     /translation="MNSKIYYFSGTGNSLVVSNILKETLNGSKEVIPLAIHRKENNID
                     INEDILVIVFPVYFADVPDIVKSFVEKLNFNINTHIYAIATCNGVAGHSLFTIDKLLK
                     KRGKKLSAGFLINMPGNALITPPDVEEERLKNQTNRVAEIAKCINNLEIGNIEGKNNL
                     KSHIDSVVLRLVGKNMQIATTKFFAENKCNGCGTCKRVCPVENISIVDKKPKWGNECE
                     RCLACFHWCPKEAINVKKSFLTNRKKYHHPDITVKDIFLDK"
     gene            complement(26173..26634)
                     /locus_tag="PC494_001066"
     CDS             complement(26173..26634)
                     /locus_tag="PC494_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HDF3911586.1"
                     /translation="MGGARDYLNGGKMKDFEKLYEATTKLVSTSLKVKDDLKKMFKQN
                     GYDITTDHYALLRFLWEQDGISQIDLCEKSCKDKSNTTRILDVMKNKGLIVRKVDVKD
                     RRKFQIFLTDLGRELEEPLNEIASIYATETFKSISDEELPLFTDILDRIGK"
     gene            complement(26610..27287)
                     /locus_tag="PC494_001067"
     CDS             complement(26610..27287)
                     /locus_tag="PC494_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HDF3911587.1"
                     /translation="MIITVINGSPRKNGATSKVLTYLYKDIERLIPDVKINYFDLSEV
                     NPSYCIGCLNCYKMGKCINQNDKVEYIHDIITKSDGVIFGSPTYGSSVTGLFKVFTDR
                     AHMMLERLLYRKPCIAVTTYENARGSKAISFIKSMVLDSGGYVCGSLSIKTGFNQNPI
                     TEKVESKIQKVSKKFIYCIEEKKNPPVLSQIYNFIAINAVLKPMAFKDIEQYKGIIDR
                     WEEQGII"
     gene            27520..27906
                     /locus_tag="PC494_001068"
     CDS             27520..27906
                     /locus_tag="PC494_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HDF3911588.1"
                     /translation="MKKLPHISEAEYQVMKIIWKYAPISTTEVIEKLVETSTWSPKTI
                     QTMLLRLVKKGALTYEKNSRVFVYTPLVKEEEYVARESSSFLNRFYNGTLNSMVLNFL
                     ENDKLSEDDIEELREILNKRTTKGDK"
     gene            27909..29708
                     /locus_tag="PC494_001069"
     CDS             27909..29708
                     /locus_tag="PC494_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaR1 family beta-lactam sensor/signal
                     transducer"
                     /protein_id="HDF3911589.1"
                     /translation="MYAPFFIRFLLSTLTLSILIVVILLAKKVFKKHISAKYQYNIGF
                     ILLIMLIIPFVPLKYINLGNVFNYLYTFNQLGSSTNRTSMIKNSPNSVINNSNALNDF
                     SVSLNQVNFDSLNILLLISWIIGILIMIAITIHCNIKIKNMKKSIQILRDDEIVFIFE
                     KCKKDIGINKDFILCKSPIINTPITFGYFKPHIILPDKSISKLSLKDIKYILLHELQH
                     FKNKDILINYIMCFLQILYWFNPLVWYAFKEMRIDREIACDISVLKKLDKDSHIEYGQ
                     TLINFVDNISRPSNLTLTSDIGGSKKQIKKRLLKIMDFHNESNTLKFKSILIFTLIAL
                     IVFGNIPKLSIMADINEKYRPTNEQTVYEDLSQYFKGFDGSFVMYDLKSKQYHIYNKE
                     KSKTRISPNSTYKIYSALLGLENGIITRNNSHIPWDGKHHSNSSWNEDQDLFSAMENS
                     VNWYFQTLDKKTGLKNIQTYLRQIGYGNYDVSGGISNFWLESSLKISPIEQVELLESF
                     YTNKFKFEDKNIETVKDSLLISKKDGVSLFGKTGTANINGKDVNGWFIGYVEKNENTY
                     FFATNIQSKDYSNGSSASKITLSILNDKKIYNP"
     gene            complement(30063..31937)
                     /locus_tag="PC494_001070"
     CDS             complement(30063..31937)
                     /locus_tag="PC494_001070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HDF3911590.1"
                     /translation="MNKYNKIANELIKIIGEDNIISITHCATRLRVMVKDREIINDKK
                     VEKVDEVKGVFFTSGQYQIILGTGIVNKVYAEVEKMGLKTLSKKEQDELVKNNETGFK
                     KVMRTLADIFVPIIPVIAATGLFLGLKGCLFNDNVLGLLGMSSANIPLYIQTLVSVLT
                     ETAFAFLPAIIVWSAFKVFGGTPVIGLVIGLMLVSPILPNAYSVADPSNEIEAIMAFG
                     FIPIVGCQGSVLTAIVTAFIGANLEKWFRKHMPNVLDLIFTPFFVMLITMLVILLGVG
                     PIMHTIELKMVDIISLLIDLPLGIGGFIIGFTYPLAVITGLHHTYVMIETSLLANTGF
                     NALITLCAMYGFANIGTCLAFMKKSKNNQVKQTAVGAMLSQLFGISEPVLFGIQLRYN
                     LKPLIIMCASSGLGAAILSILHIQSNSYGLAVLPSYLMYIYDGYNLITYLLVSIFVVA
                     FCFIVTCLFGVPKEAINEDEDEELVFNENNENFVSPAKGKIVALENVPDETFSKKMLG
                     DGFAIDIIDGKIVSPISGKLETVVSSGHAFGIKGTNGEVLIHVGIDTVALNGDGFDVA
                     VKQGDMVKQGDVLVNVDLKRIHELGKSTLTMVLFPDGKKVNILDINKDVKIGQRICVE
                     "
     gene            complement(31942..33606)
                     /locus_tag="PC494_001071"
     CDS             complement(31942..33606)
                     /locus_tag="PC494_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HDF3911591.1"
                     /translation="MEKKWWQKEIVYQIYPRSFQDSNNDGIGDLQGIISRLDYLKDLG
                     ITSLWLCPIFKSPMDDNGYDISDYLDIASEFGSMEDLKELIKESKDRGIKIILDLVLN
                     HTSDEHPWFQEALKNPESPYHDYYIFKKGNDLPNNWRSVFGGSVWEKVENRDEYYFHS
                     FGKKQPDLNWENPILRSELYQMINTWSQMGVAGFRVDAITFIKKNLSFQSLESDGVDG
                     LVKCTKTVRNQPGIEKMLYELKENTFKKYDCMTVAEAAGISYDQLGDFIGEDGFFSMV
                     FDFKHADLDVASGSEWFKRISWTIPDLRKCILDSQMYVQEHGWAANFIENHDQPRATT
                     KYLLQYERNDDAVKMLGAMYFFLRGTPFIYQGQELGMTNFKRDTINDFNDLSSIDQYY
                     RSIDEGYSEEEALEFVNLRSRDNARTPFPWADKENAGFSDTTPWLKVIENYKDINAQS
                     QINNSESILEFYKKMIKLRQDSEYSDCLIYGSIEPIDIESEDVIAYRRQLDLVVIDCY
                     YNFSDKPVEIRVEEKYDIVFQNLDDINLLNKTVCLKPFHAVLLKAR"
     gene            complement(33620..34441)
                     /locus_tag="PC494_001072"
     CDS             complement(33620..34441)
                     /locus_tag="PC494_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HDF3911592.1"
                     /translation="MKLYKLLILDIDGTLRDEVYGIPESAKHAIRLCQKNHCSVVICT
                     GRSMGTIQDDVLSLGVDGYIAGGGNYIQYHGELLYNQSFNQRLIKEVVCLLKKREVAF
                     SIESQEKVFMNQKAKEIFETMNQLKGTNSCINKQHIQEKITYENNIEEYKSQDIHKIC
                     LWSNEKVFDEVKDILQDKMELAQRDISSQYYEIIQKDFHKGKAIKRLQERLGVTQKET
                     ICFGDGQNDIVMFQASDVTIAMKNSHQQLKDIATSICEDIFDNGIYKELKRRNII"
     gene            complement(34540..35304)
                     /locus_tag="PC494_001073"
     CDS             complement(34540..35304)
                     /locus_tag="PC494_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HDF3911593.1"
                     /translation="MKIEGLFNKYYNSFTANDKYICECILNHKEDCIKLSIDEFADKY
                     HISTSALSRFAQKLQLPGYSELRVIIRLNETEVEYKNQSKHQLMDCYNKVIDDIEKKD
                     CSIMFERMKKANRIIVFGEGYSQERVAKEMKRIFLPTGKIIYDVYGYDMIQALNHFIK
                     TDDMIFFISLNGDASTIIDFAKEMRMKGIYMVSITKMISNPLARLCDENLYIQSISIS
                     VDKQLDYDVTTPYFILIELLYIKYKMYLESEHIPRK"
     gene            complement(35301..36050)
                     /locus_tag="PC494_001074"
     CDS             complement(35301..36050)
                     /locus_tag="PC494_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HDF3911594.1"
                     /translation="MRLESLVNQNYDNLNENDKIIIKQILICQREYRNFSCEKIANEC
                     NVSRATLLRLCRKIGLDSFSDLKYLLKNNQLEFVNNDNNFHDVCENYRLLMNELQKIS
                     FQDICKIIYDAETIYIYGTGNEQKSLAQEIKRIFLSVGKCVIDLFDIGEIEFMRESFQ
                     KSDLFIIISLSGETKAGIEIAKFINNHIHTISLTRLDNNTIATLCEYNLYVETQKLDT
                     LQAISYEVVGAFYALLDLLHMNYIEYRRRKE"
     gene            complement(36554..37159)
                     /locus_tag="PC494_001075"
     CDS             complement(36554..37159)
                     /locus_tag="PC494_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HDF3911595.1"
                     /translation="MKIKENVLMLDSTRGSNCFIVFDKEIILIDTGLPFMGENIIKEL
                     KTLGIKLTDIKHILLTHHDVDHISNIKLLKEKTGAKVWAHVEDIPFIIGEKDRPGFKK
                     FIGKAISRRLIKDVEPYGENMQIGNIKIIHTPGHTPGHVCMIFEDVLFAGDLVKNKNG
                     NIVPYPNPWNWDYKKMMKSISELDNLKYEWICMSHGTPCIK"
     gene            37338..37976
                     /locus_tag="PC494_001076"
     CDS             37338..37976
                     /locus_tag="PC494_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDF3911596.1"
                     /translation="MSELSKRDKEKIQRENEIIDKAEKLFCLNGFDNTTMNELAKEVE
                     YTKRTIYKYFSCKEDLFFAVVLRGYKRLWDNVKIESAKGKTGFEKIKLSYFAFHKFYS
                     VEPSLLCLMGMIGIVNSEKSDTDMLFKEKFFSFNKFMFDEIQGMFEIGKNDRSIRHDI
                     EIPTLMYSSIFTLTGFFNLLSVTGKSYLNNFNIDEEKFIETTLALLIDSIKA"
     gene            38108..38770
                     /locus_tag="PC494_001077"
     CDS             38108..38770
                     /locus_tag="PC494_001077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF3911597.1"
                     /translation="MAKILLLEDDDTITFGIKTSLEKKNHTVCCYNTIAEAKKNFDKT
                     IDLILLDLNLPDGIGYEFCQYVKSIEDTPVIFLTVRDDEKDIIRGLDMGADDYVVKPF
                     LLSVLQSRINAVLRRTHSNTNNTITCENISLNKVEVKAYLDNVEVPLTAGEYKLLLSL
                     MENKNRAMTRTKLLEMLWDVDGNFVNDNTLTVTIKRLREKLKNPPCIKTLRGIGYRME
                     DN"
     gene            38770..39951
                     /locus_tag="PC494_001078"
     CDS             38770..39951
                     /locus_tag="PC494_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF3911598.1"
                     /translation="MKTPRNINSTVVFIIFCLIVTFLLSVILTTITSFNEYNVLSKAL
                     GASYEYNPKSTESILKSLKNSSDKDFKTGNEILSKHGYSKSTFWSKNFFYFLVISFGI
                     ISTMATVVYIIKHRTNKQKLSRINNLTQYLEEVNLGKESVLLRCEDEFSHLEDEIYKT
                     VGELRCSKEFALKERQTLSDNLADIAHQLKTPITSMSLMAQLLSENCPDEEIDYINRL
                     TNQISRLERLVSSLLTLSKLDASTLIFESKLIDVHSLLTYAIEPIEGSLREKHQTFTI
                     EASPSVEFEIDINWTLEALLNILKNCSEHIEDGGYIVAYYSQNPLYVEIIIEDNGKGF
                     AQEELPYIFNRFYRGKNASKDSIGIGLALSKSIIERQNGTIHAENCHNGGARFIIKFY
                     T"
     gene            complement(40132..42792)
                     /locus_tag="PC494_001079"
     CDS             complement(40132..42792)
                     /locus_tag="PC494_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF3911599.1"
                     /translation="MNILQEYTLDFVRRNKRSSIAIMLAILLTTTMMSSLCGLLYTMW
                     TDFIKLSIEKEGNWHGELFDYTYGSDLPLIENFSSVDDVMVKGQWYVGKINDEKRDYI
                     IYRNATSEYWNSMPEKDTIIEGRRPNNANEIALSKQYFENNPSVKIGDKITLPIGDRI
                     LNGKPLEPIAPKSKGESFKKISEATLTIVGKVDVSTSSVIPAYTALGYLDKTSIKPND
                     SITVYLRFKNIRDTYKELPKLAKSLGWKTNEYGKYNLKYNSNYLLKMLVFSPEQKASM
                     SSISKFSTPIMYLTIAIFTVAVFVMVIYNAFSLSANARLTQLGILSSVGASPKQIKRS
                     VVFEGFLLTIIPLPIGLFLGWLLCNRLIVYVNSVNYHTDVPEVVFTYGIPAFLPAVLL
                     TIVTVWISALIPARKVSKISPIEAIRQGDSVKIKKSHKYSLGKIFGIEGELASNALRA
                     RKKSYRTATISLTLSFLLLTCFLHIIANQEGAKAVYGSDNYKDQRDIAVYLENSEPVE
                     SAFIEKLDNTEGVKSSLYYQKMSASTWLTEKDASKELAKNGGFKNIASSKKYSPIERD
                     GKFRIISNIIGLDDKSFTEYCRQISVDPKLFYDTKNPTSIVYNKEEDINRSTRRNKVY
                     IDYLNLSIGDNIKLNEKVYDEDKGDYTYNMKVGAITSTLPKIVDTSSKYTLMQIVPMS
                     MVQEISKNYDEVSRLRSNRLIGVFKVNNREDIPRVREKLESIYNKDYGSGDYSIEDVL
                     ESEKQDASGIKTMNLIVGFITGLLAMIGLSNVLATVSGNIRSRRQEFAMLRSVGLSPE
                     GIKKMLILEGLFLGITPLLLSIPVQIGIVYAFLRINEIYFIEYLPFAPISTIIGFTIL
                     ILFIVIASYMTGYKQLKNENIVESIKNETI"
     gene            complement(42789..43472)
                     /locus_tag="PC494_001080"
     CDS             complement(42789..43472)
                     /locus_tag="PC494_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF3911600.1"
                     /translation="MEILKCENLTKIYGSNQTRVTALNNVNLSVQKGDFVSIVGASGS
                     GKSTLLHLLGGVDRPTSGKIYVEDTEIASLKEEALAVFRRRKVGLIYQFYNLIPTLDV
                     RKNILLPMLLDKRKVDEDRFSEIVSILGLSDRLNHLPSQLSGGQQQRVSIARSLIYRP
                     AILLADEPTGNLDRKNSEEIVDLLNLSNKRFNQTILLITHDEKIALEANRIVTMEDGV
                     IVSEKVVKK"
     gene            complement(43816..44769)
                     /gene="blaCDD"
                     /locus_tag="PC494_001081"
     CDS             complement(43816..44769)
                     /gene="blaCDD"
                     /locus_tag="PC494_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDD family class D beta-lactamase"
                     /protein_id="HDF3911601.1"
                     /translation="MKRKKNFIWIAILLVGVVMVMYYLGKKHNDINQKTDKNYIKSEL
                     NKSELNKSKIENNDKNKKEKINMVDYSDCFEDISGGAIFYNTKNKEYNIYNKELIETR
                     RSPCSTFKIVSTLIGLEKGVINSKESVMGYDGTEYPNKNWNKNLSLEEAFKESCVWYY
                     KKLINKVDAKYVQNILDDLKYGNCDISEWEGDLKNGKGHLNGFWLESSLQISPKEQVQ
                     TMAKIFEGDTNFKKEHINILRDIMKIDVNDKNINVYGKTGTGFDEKNKRVDAWFVGML
                     EREGDTYYFAIKSDDSNKEITGPKVKEIAINIIKKYYSVRE"
     gene            complement(45310..47424)
                     /locus_tag="PC494_001082"
     CDS             complement(45310..47424)
                     /locus_tag="PC494_001082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding domain-containing protein"
                     /protein_id="HDF3911602.1"
                     /translation="MSENKQVVNCDIIASNSKHNMCEYDAELLTFFPDEIAHLIEINN
                     KLDNAFKKAENLVDKLDKDYMDAKMYMVKNRGEIDPHEMFQNEQGLKQIDNYGAFMVK
                     VRDKINKIKDSPYFARIDFRLKDMDDESKYYIGRFAFDYEDELIILDWRSPIASMFYD
                     YEIGKAGYDAPIGWVDGEITRKRQFKIKNGKLEYALESSINIQDDILQKELSHTSDEK
                     MKSIISTIQKEQNQIIRNDKADTLIIQGVAGSGKTSIALHRIAFLLYRFKDKISANNV
                     IILSPNKVFGDYISNVLPELGEEPLCELSFENIAEVQLDRVINFESEKDPLEINDAKW
                     SERVRFKSTLDFVKLIDDYIKQMPNKIFIPKDYTFGSFTAKSDWIQSRFEAYNRYPVK
                     KRLEKVAEDIHYKFESDNIMEEDLPKVKSILKSLNGMLTIKNTLTLYKDFFKQMNISN
                     MFVMATKKTLEWSDVYPFIYIHAAYEGIQEDKIIRHVVIDEMQDYTPIQYAVINLLFK
                     CKKTILGDFGQLVNPNHTHTLDDMKQLYNDGELVMLNKSYRSTFEIINFAKKIQDISS
                     LEPIERHGEEPALLKCNNEQDEINKIKIEIEEFKKSDNATLGIILKTDNDAKAVYDAL
                     REKYSVHLISSESSSFTKGVSITSIKMSKGLEFDEVIVPSVNNKTYYSDYDRSLLYIA
                     CTRAMHKLKLTYTGELTQLIDM"
     gene            complement(47508..48344)
                     /locus_tag="PC494_001083"
     CDS             complement(47508..48344)
                     /locus_tag="PC494_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF3911603.1"
                     /translation="MSYKVINVITAIDYIEEHLSEKLDLDIVANAVHYSKYHLHRTFT
                     TSVGLTMHDYIKRRKLTEAAKLLAFSKKPIIEIALIAGYESQQAFTSIFKAMYKKSPN
                     KYRKEQEFYPLQLRFVLKKDNLFSKNVLELEKEIKLASMSDIPLWMNLVRLVIDGFPN
                     LQEEEYIYQLEQYILEERALILKLNNVAIANMVFNRETRSIDFFGIHPQYRNSDIAQV
                     FLKKVIEDFLIDTDISITTFREGDKADTGHRDMIKKLGFAEAELLVEFGYPTQKFILP
                     LS"
     gene            complement(48939..49301)
                     /locus_tag="PC494_001084"
     CDS             complement(48939..49301)
                     /locus_tag="PC494_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HDF3911604.1"
                     /translation="MKIYDILTRFYIQDIEKAIPFYENLLKEKCSLRFSYKEVGLELA
                     QIGNVLLLSGSDDALKPFIETKSTFMVDSVDEWRSYLLDNGAVVVRDKKKVPTGYNMT
                     LRHPDGTIIEYVQHTKQD"
     gene            complement(49535..49999)
                     /locus_tag="PC494_001085"
     CDS             complement(49535..49999)
                     /locus_tag="PC494_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HDF3911605.1"
                     /translation="MTRISNITIAEQSEYCFLAIRKTIDFMVEFSEFSKQSFEKISKY
                     LEERGILSSGAPIVCFHNMDLAKLDVEVGFPVATYIDGKNEILQRIVPAQKIITAIDL
                     GPYELQDPTLEDLFSWANSNGYKLHGDIYYQYLNDINRPASEYLTKMMLPII"
     gene            complement(50428..51849)
                     /gene="nhaC"
                     /locus_tag="PC494_001086"
     CDS             complement(50428..51849)
                     /gene="nhaC"
                     /locus_tag="PC494_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HDF3911606.1"
                     /translation="MKERECRKASLFDAMIPITCLILFLSLGVLVYGSSPHVPLIGAA
                     AVAGLVAVYRLGFKWKELELSMFNSIKMAMQAILIIIIIGVLIGTWIVSGVVPCMIYW
                     GLKILSPNIFLVASTLVCAIVSLATGSSWSTMGTVGVALLGIGQSLGMPIGLIVGSII
                     SGAYFGDKLSPLSETTNLAPAMAGTDLFTHIKYMLYSTIPSLLICLVIYGVIGMKYSG
                     QALDIKQIELIRSTLDSTFNTLSPVLLLAPAIVIGLVVFKVPAIPGLIVGAVLGVLFA
                     VVFQGESMNTILDAAQNGYVSSTQIQEVDALLSKGGIMNMMSTVSLTICALSLGGILE
                     KTGMLEVVASSLLRLAKGVFGTVLCTMVTCTITNIIAGEQYLSIVIPGRMYNKEYKKR
                     GIHPKMLSRALEDSGTLTSPLVPWNTCGAYITATLGVSALTYGPYALLNIINPIVSLV
                     LIACKFKIARIEDEPETCLNFDV"
     gene            complement(51879..52943)
                     /locus_tag="PC494_001087"
     CDS             complement(51879..52943)
                     /locus_tag="PC494_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine/ornithine racemase family PLP-dependent
                     enzyme"
                     /protein_id="HDF3911607.1"
                     /translation="MYPRLEIDIEKLKHNAKLISQMCHERNIKISFVTKSFCAQKEIV
                     EEICSEGIDHIADSRIQNLKNLQDINLPKILIRIPMLSELEEVINYCDISFNSELGTI
                     KKLNELCESKNIIHKIVLMFDLGDLREGYFYEEDFFSNVREIVRLKNIEIIGIATNLT
                     CYGAIIPSRENIGRLVSIAKRMEEKFGINLEIVSGGNSSSIHLLINNNMPEGITNLRI
                     GESILLGRETAYGENINGTYQDAFKLICQVVECKEKPSVPIGEIGVDAFRNKPVYEDK
                     GILKRAIIAIGKQDINIDSLIPIDTDIKILGASSDHMILDVSNTKYDYKLGDNLEFLL
                     TYGGIMSSSTSKYVSKKIIV"
     gene            complement(52928..54337)
                     /locus_tag="PC494_001088"
     CDS             complement(52928..54337)
                     /locus_tag="PC494_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate mutase L"
                     /protein_id="HDF3911608.1"
                     /translation="MENSKVSLKIDVLVAEIGSTTTVVNAFHDINTNNPIFLGQGQAP
                     TTVFEGGDVRNGLSGAIKDLANKLSVDDIKYNDMFATSSAAGGLKMTVHGLVYDMTVK
                     AAKEAALGAGAVIRQITSGRIKRTDLNKIKEINPNIILIAGGVDYGERDTAIYNAEMI
                     ASMNLGIPVIYAGNVENQEEIRLIFEDTNYKLYITENVYPKIDLLNIEPTRRIIQSVF
                     EEHITTAPGMKYIKEMVNENITPTPGAVMEASKLLYKNIGDLLTLDVGGATTDVHSVT
                     DGSDYINKILVNPEPTAKRSVEGDLGVYVNMKNIVEVIGKENLQSELSIDIDAVIENY
                     PPIPKSKEEILFVERLTKEAVVKAMLRHSGKIRNIYGTTGKVKIAEGKDLTEVRYIVG
                     TGGALTRLPSRIEILDNMLKYNKNNELLFPKEKTKILIDNDYIMASMGVLSKKYEEAS
                     LKLLLKSLNFEEERLCILG"
     gene            complement(54337..56541)
                     /locus_tag="PC494_001089"
     CDS             complement(54337..56541)
                     /locus_tag="PC494_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892628.1"
                     /note="Presence of a B(12) (cobalamin)-binding domain
                     implies dependence on cobalamin itself, in one of its
                     several forms, or in some unusual lineages, dependence on
                     a cobalamin-like analog; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalamin-dependent protein"
                     /protein_id="HDF3911609.1"
                     /translation="MLKENKKLDIDYILKDLDKYKPKRRGWVWREHLENLEMGPFKYK
                     DCTKPLKKSVGLPSSKYFNNIDPQPSPVITTEIASGRFEDDIRRMRMAAHHGADHLMV
                     IRTAGQSHFDGLIEGTPQGIGGVPITRKQVRAQRKALDFIEEEVGRPINYHSYVSGVA
                     GPEVAVMFAEEGVNGAHQDPQYNVLYRNINMVRSFVDACEAKKIMAFANIAQIDGAHN
                     ANATAREAWKVMPELMVQHALNSIFSEKIGIDKSNICLSTVPPTAPPAPCLKIDLPYA
                     VALRELFSDYKMRAQMNTKYMESSTREATVTHVLNLLTSVLTRADIQSTITPDEGRNV
                     PWHIYNIEACDTAKQALVGMDGLMDMIELKDVGELRDKARELKERAVLYMEEISEVGG
                     YFESVEQGFFVDSGNYPERNGDGISRKIKGGVGEGTVYEREEDYLAPVTAHFGYNNVA
                     QYDENAIDNPSMLIDGCTFENPDKIIYIDELDDFDNVENRLKESYEYRNGTKIKPEME
                     WCADGIVMITMMLPTDKRTAEFAALEFVKKMNLQEIEVISREVMHESEGTRIEVKGRV
                     PFDIDLNNLVIPEEPKVLTDEEIRADIEEKPMKIVSATVGEDEHSVGLREIIDIKHGG
                     IEKYGIECHYLGTSVPVEKLVDAAIELNADAILASTIISHDDIHYKNMKKLHDYCVEK
                     GIRDKVMIACGGTQVTPEIAVEQGIDAGFGRNSKGIHVATFLVEKRREMSNK"
     gene            complement(56535..56909)
                     /locus_tag="PC494_001090"
     CDS             complement(56535..56909)
                     /locus_tag="PC494_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine aminomutase subunit alpha"
                     /protein_id="HDF3911610.1"
                     /translation="MKKREDDFEVRRKHLQELSDDELKERFWSLATQIVEPMIELGKK
                     NTTPSIERSVLLRMGFSSLEVKPILEGVMERGLIGKGAGHVVYKLAKSKNITVREAGL
                     LLVKGEYWDEVTCLFREGVESC"
     gene            complement(56987..58417)
                     /locus_tag="PC494_001091"
     CDS             complement(56987..58417)
                     /locus_tag="PC494_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent lyase/thiolase"
                     /protein_id="HDF3911611.1"
                     /translation="MNNSTSMKDMSYQAVMGRNNEIMKNAIGLDYSSFEQEGIGFDYE
                     KMMSETGYTLQDIEAIQSQYAVGNTPLIELKNLTKLARKCAKEGKGARIFVKDEAMNA
                     SGSFKARRAATAVYHAKQMGYKGVIAATSGNYGAAVASQAAMQGLKCIIVQECYDSNG
                     VGQPEIIEKARKCEAYGAEVVQLTVGPELFYTFLVLLEETGYFNASLYSPFGIAGVET
                     LGYELAIQFREKYKKDPDIVVCTNAGGGNLTGTARGLIKAGSINTKVVGASVDLKGLH
                     MASDNQFNKKSFTTGHTGFGIPYCTWPDRSDVPRSAARPLRYMDRYVLVKQGEVFYTT
                     ELLAQLEGIERGPAGNTSLAAAFSLAQELDEDKAIVVQETEYTGAGKHICPQLTFARE
                     NGIDIKFGNPREEIAGVNLILPERPELLKCVDIDMNKIRKSFIKNCISNNHIDNIDKL
                     SNRDIEFLMEEVKSSRDFVVDVLNNL"
     gene            complement(58410..58718)
                     /locus_tag="PC494_001092"
     CDS             complement(58410..58718)
                     /locus_tag="PC494_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-ketopentanoate thiolase"
                     /protein_id="HDF3911612.1"
                     /translation="MDAKINDWVIIHNIVLTPEERAPQVPEDTKKVSLEMWVKGFIQS
                     DASIGDLVEVKTITGRLVKGNLLKINPYYTHDYGKCIPELLQIGIQAKEILFGGVYNE
                     "
     gene            complement(58839..59906)
                     /locus_tag="PC494_001093"
     CDS             complement(58839..59906)
                     /locus_tag="PC494_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-binding protein"
                     /protein_id="HDF3911613.1"
                     /translation="MRKVRVGIWGFGAMGIGMANMILKKEGIEIVSVCSRSTSGKSMY
                     NVLGIERGERPEVIINKNYEEVFREKSVDVVLLATDSFTKKAFDKIIFLLNRKINVIS
                     TAEQMAYPQADDADLAKKMDEVAKENGVSILGTGINPGFVLDLLVLALSGTCEEVTSI
                     KAKRVNDLSPFGKSVMVEQGVGVTREEFIKGVEDKTIAGHVGFVESINMIADGLGWKL
                     DKIEQTKEPIMTTVDRKSKYGEALAGNVAGCRQCGYGYVNGEVLIEMEHPQQIIPEAE
                     GIKTGDYVSIKGIPNIDLQINPEIPGGVGTYAMIVNSIPLIINARPGLKTMLDIPVPR
                     AIMGDIRNQIEVELEEESKAN"
     gene            complement(60162..61535)
                     /locus_tag="PC494_001094"
     CDS             complement(60162..61535)
                     /locus_tag="PC494_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDF3911614.1"
                     /translation="MNEILENIDEGVHFVNKDGKTIIYNNSVQKMEKMNRHDILTNSF
                     FDIVNKMKINRSTLLEVLEKREVIKDNIQKYLDKNGKEITAINTTIPIDIKGEFVGAL
                     EISKNMTTIENLLNRNYKKNLVNKVSSRQKKGYEFDDILGESNLIKEAIAKSKKACKS
                     DASVFIYGETGTGKELFSQSIHYGSNRKNYPFIAQNCAALPESLFEGILFGTSKGGFT
                     GAIDRPGLFEQANKGTLLLDEINSMPIMLQAKLLRVLQEGYVRRVGGTKDIPIDVRII
                     ATTNESPKVILNEHKMRKDLYYRLNIIHIKIPPLRDRKEDIPLLCKKFISKYNKKLNK
                     KVVGISDEAIKILKNYDWQGNIRELENIIYCTMSMMEDEVQIETSMINLNDYYNLKEN
                     KESNNYSLNDLEDKTLSKIISEIEEKYIYESLEKASYNITKAASILGMNRQNLQYKIK
                     KYNIKIL"
BASE COUNT        20689 a        10443 c         7284 g        23233 t
ORIGIN      
        1 acttctattt ctcctgtatc tgctatttta ccacttgatg tgtgtgtcac tgtaaatact
       61 aatgttactt ttgtttctgt atctggtggc actattgttc catctttcgc tataacactt
      121 tcatttgttg atgattttat ctttattgtg tatccacttg ctactgttgg catagttagt
      181 gttgttgcat cttgtgttgg ctgagttaca cttgttattt tatccgcctc agcttgtact
      241 tctgcttgta tttccccatc tgttgatttg gctggtacta ctacatctat ttctcctgta
      301 tctgctgttt taccacttga ttcttgtgtt actgtaaata ccaatgttac tgtttcctct
      361 gtatttggag gtattattgt tccatcttcc tttataacac tcttattgct tgatgttttt
      421 attgctatag tatatccact tgatactgat ggcatagtta atttagttgc atcttttgct
      481 ggtgcaggaa cgcttgttat ttttgccact tcattgtcta atgctgcttg taattcttca
      541 tctgttgatt tagctggtac tgttacagat agttcttttg tatctgctgt tttaccactt
      601 gatgtatgtg ttaccgtaaa tactaatttt actgttgttg ctgtatttgg aggtattatt
      661 gttccatctt tttttataac actctcatta cttgatgttt ttattgctat agtatatcca
      721 cttgatactg atggcatagt taatctagtt gcatcttttg ctggtgtagg cacgcttgtt
      781 atttttgctg cttcattatt tactgatgtt tgattagaag aacttcctcc tgaagatgag
      841 cctcctccat gtgaagaacc tccacttgat gaacttcctc ctgatgaatt agaacttgga
      901 ctatttccac ttattgttgg agaattatct cccttaacac tacttattgt acctttatta
      961 tctatagtag tccctttaga attatttgta actgtagtta tcttaccacc attagtcact
     1021 tttacttgac ttgctccaga tgctactgtt aaactaccaa tctcaccttt agaattattt
     1081 tctatcttgg ctccattttt atcattaacc tttaagttag ttatttttcc atagttaaca
     1141 aaagttccat cttttacatc atctataact aaatcatcca cttttgcata gttatttaca
     1201 tctccattag gcatgttgat agttacagtc tttgtatatg taccatttaa gtttactgtt
     1261 actgctttat cagtttgtat tgtaaatgct tctttaacct cactagttgg cttaaagttt
     1321 ataacatcat tagcagtagc tttatctata gctgatttta attcagaaat tgttttagct
     1381 tcaactgttt ttacttcttg taatgacttc atttcattaa atgctgtctc attaccattc
     1441 ccaccaactt tagttatctt atcaaaactc ttagagttaa ctagagattt ttgtgaagct
     1501 gataagttct ttccaactaa aactactggt gattgatttt tagcacctaa tacacctact
     1561 gctagtgcat ctataagttg gtcttgttta ttcataccat ctttagttac ataagcattt
     1621 tttaaatctg tctttttata aaattctttt attacttttg catttgtatc atttctatct
     1681 gttccaccta gtcttgtact atttggtagt ttatttttaa cagcttcaga aattgaactc
     1741 tctccaccta ctacataaga ttgagttatt ccagcatctt ttataaattt gtctgcaact
     1801 gctgttccat ttttagaatc agcaagtatt actggcatat tgttttgtgc agctggtgct
     1861 cctacactta cagcatctgc aagtcctttt tcaccattaa ctacagctat tttcttaaca
     1921 tcacttatag catctaattt ctttgctaat tctaaggatg tttgatatct ctcagctcca
     1981 gagattctct caaaagatat ttttaaattt tttatttctt tttctatatt tgtacttaat
     2041 acagaagttc cacctattaa gtatactttt ttagctttta atctttgtat ttctgctttc
     2101 gtcttatcat ttaatttatc tttacttgtt aaaagtattg gagcattttt tgcttttgca
     2161 aatggtgttg cagatagagc atctgctata gatgagtcgt ttacgattac tacctcatca
     2221 gcatttttcc atccatcttg acttatttta acagcagttt catatctttc ttgccctgtt
     2281 aaatttgttg ccacagtttg tgcactagct atgcctgctg ttgaacttcc agctatcatt
     2341 gtaactgtaa gcattgcagc aatcttcttt ggtattttca ttttattttc ttcccccttg
     2401 tccatttgat attacttaat tttttaactt tgttcccgtt ctaattctaa aggatactta
     2461 atatctaatt ttaaagaggt ttctaactat aatgatttca taattaattt gtaattattt
     2521 tgttacattg cagtcattat gtaaggaata aagaaatttt cttattgatt gaaaaatttg
     2581 taaatttata ttttaaggta agtttgattt ttatgttaat gaattgttat aaaaaatagg
     2641 gttttgtata aaaaaagtag cctttagaat taaaagtgct actcttttta caaataaatt
     2701 ttattattta tacttgtaat tatatattaa ataaccaatt ttatccatat gaaaaacaaa
     2761 taattgcgat atttttttaa ttattcttta tatttacatt ttaattagaa ttacttttat
     2821 aaagattata tctgttgcat atactacttt aagtgctaat atatctcccc ctaaattaga
     2881 atcctcgtta tctcaataga cgttttctac tgtcaaagtt accaacattt gaaacttatt
     2941 aaatttttat ataaaaaaga cctagaatat aaattccaag tcatttttta ttaaatttat
     3001 tttttacaat ataatattgt catgattaaa gaacataaat catacacaaa ttggtcataa
     3061 atcttacata aatcatctac aaaaaataca ttatttatat taaatctata taactaaatt
     3121 aagagcatat tgtacaatat gctcttagaa aagatatttc ttgtttatag tttatagtat
     3181 ttctctatga tttttatttt tatcatttca aaaataaaaa ttaagattac agttattatc
     3241 atattttgtg tactattttc tataatatta taatgaaaca atgaaaaaac aataattaat
     3301 gaaattacgt ttatagcccc agaaatcaaa aatgcctttt tcttattatt catatattcc
     3361 ctctccagat tatctaaatt agtctatatc aagcattttt aagtacttat cattaacttt
     3421 atatatattt ttttctttag acaaaatctc tatctcttca agattactaa acacttccat
     3481 caactggtca actaattcaa tttcctttat tccagccttt aagtatctac ttttattctt
     3541 ttttatataa ttttctaatg tcatagaata gttatcttta ttgcaaatat attttaatat
     3601 atgttcttct gttgctgata gagttatgtc attttcaaac aattcttctt ttaatatact
     3661 ttctaaagat tttctatcat gcatattacg catctcatta atagattgta ttatagactt
     3721 gagcataaac tctataaata cagttaaatt atttcctttg ttttctacat caagtatagc
     3781 cttataatac ttagttctgt ttttagatat catatatgat attgaaaact ccttgaaagt
     3841 atcatatcct ttatcaatca aatatagata tgataaggct cttgatgttc ttccattacc
     3901 atcactaaaa ggatgaacat atacaaagta aaaatgaatt atagcacttt taattaaatt
     3961 acttactttg ctattttcca taaaatctat taatttactc ataaagtcat atatcttcaa
     4021 aggttcaagc cctatatgta taatctcacc ttttgaatca catacatata ctttttcagt
     4081 tctatactca tattcttctg aatccaagca gttttcgccc aatatatgat gcaaatcata
     4141 tataaatttg tgactatata atttatctaa gttgtctaat ccatattcta aggctctatg
     4201 attattgtaa atcatatatt cacttttatt actaggtttc atctttcctc taattataga
     4261 ttttgcaatc tttctagttg aaaaagcacc ttctattaca ctagaataat aagactctag
     4321 tgccaaatca tttttatctt ctattgtttt aaatatctta cttgatgtta atttatctat
     4381 ttcatttatt aaatttaata tattttcagt ttcatgatag tatagttctt tattatcaaa
     4441 actatttaga gaaagtacga ttttatttcc agtaaagtat ttgtttttgt attcttctat
     4501 tgtcagttta atcaccacct tagattatct ttatctatta atattaacaa aaagtattaa
     4561 tttttacact atttttgatt atttgtttta taattatcaa actcaattta gcgttaaagc
     4621 ataataaatt ttaataaata atgcaaaaat ttaagaataa gcatttaaaa tatatgttac
     4681 aggaagttta caactattat ttataataca ttagttatat attataatat ctcgacaatg
     4741 tcttaacaat atctcgatta tatattttaa tatataacta atatgttata atattttaat
     4801 taaataaatt tatatttttt tgaaattact taatatttta tataaaaatg aaaaagcacc
     4861 tcattctgat taaaaatctt tctgagatac tttttaaaat attaaatact acatatagct
     4921 tacataagtt taaaatttaa tctattataa aattacccta attgccaaac tttttaatat
     4981 aaattttcca acatcctaca aatataatca atagatatag aatcctaact tacaccaata
     5041 tatatttatt taaaatagtc ctaaaatacc tgtaatagct cccactacta tcagtataaa
     5101 cattattttt attggagaaa gacctttttt taaagcaaag agtactaata aagtaagtac
     5161 caaaggaatt aatcctggaa atatcttatc aagtaaatct gtttgaagac taaatttaaa
     5221 atcaccacta gtataactta ttggtgtaga taaattgata aacctaccta caagcccccc
     5281 catgactaag gtacctagta tagaagcccc ttctataacc ttatttacta ttccaccttg
     5341 aagtatactt tcaacagctt ttttcccata cttatatcca tttgtccaca ttccaaaaga
     5401 aattgaagtc attattatat attgagctat tacaaataat ataggtcctg caattgatgc
     5461 tcctccctca gttaaaccaa tacaaacagc caacactata ggagttataa ctccttgagt
     5521 taaagtatcg ccaattcccg ctagtggacc catcaagcct gttttgatag cattcatacc
     5581 atctccactt atttcatctg ctccattagc tttttcttct tccatagcta ttgttattcc
     5641 atgtataaca catccacata taggttctgt gttaaaaaat gctagatgag tctccacttc
     5701 ttgttttaac tcttccttat ctggatataa ttttttaagt actggcaaca ttgaatgtga
     5761 aaaagctgtt gattgcaatc tttcataatt gtaattagat tgtgcaaaga aaaaccatct
     5821 taaccatgat tttattacat ctttcttgct taacgttttc ttagatactt cattttttat
     5881 atctgacata atattttccc cctcacatgt atttaagatg tagcactatc ttttccgtac
     5941 ttaattgaag taattgtaag agcaagtatt actccaataa cagatattac tattatatct
     6001 actttaaaat aaacagccat tagtattcct aatatgaaaa agggcatagt aaacttgttt
     6061 ccaatcaatt ttaaattcat agcaatccca agtgctggca acatagcccc aattacatta
     6121 aatacatgta acacattatc attcattact tccaacatac catctatcgc atttggacca
     6181 aaataaacaa ctaataatgc tggtataaaa ctcattgcaa ataacagtat ctgtggtggt
     6241 actatattta taaatgctac tctatcaaca ttcccttttt gaacctctct atcagcccaa
     6301 tgtgcaaaaa aagaatttac tgtcatcttt ccaatccaaa gtacagttgc aacagttccc
     6361 aatggtacag ctattgccat tgcagtactt acatctagct tagatgctat agctaaagca
     6421 gtacctacat atcctgcaaa agctgggtcc cccatctgag ctccccctgc tgatataaaa
     6481 cctagatata tcatatttat acctgctcct ataattgctc cttgaacagg gtctcctaat
     6541 ataattcccg ttacaaatcc agccaataga ggtctattcc atgtaaaaaa tccaacataa
     6601 gtcaaccacg gactccaaga aagataataa aaaattgcta ttaatactgc ttgaattagt
     6661 gaaatgtgca tattcttcct ccctattttc ttttaaagat ttacaagata gtcttcttta
     6721 taataatgtt cctacatcaa ttttctttgc atctggtact atttgtataa agcatttaat
     6781 atcttttgat attagctctc taaatatttc tttttcttca tctgacacag atatattttt
     6841 ataaaaactt tttctaccaa gccctgctcc catacctcca acattcaatt cctttaaatc
     6901 taccccgcta tttactaaac ctaagacagt tttagggtat ttgaccaata ctattaaatt
     6961 ttcatctcca ttatatgatt ttaagacttc agcacctgat tctacatcat gtacttcaac
     7021 cttaacagtt gatggagctg ccatttgtaa aacttgaact ataaatgggt cctttactac
     7081 taaatcatcc acgattacta tcctttttgc tgatgtaatc ttacaccaag cagtaataac
     7141 ttgcccatgt attaatctat catcaattct tgttaatgct atattactca taattattcc
     7201 tccagatttt taatttattt tacaacttta aaacagtttt aacatctttg attcctgata
     7261 tcccaacttc ctcacataaa ttcttcaagt cttttaactt catagtatct ctgtttaaaa
     7321 ataactctaa aagcataggt aaatttacac ctgtcaaaca ttctaactca cataccttag
     7381 caaatttatt tattataata gcagatgtat taaatggagt tccgccataa aaatcaagca
     7441 atactaaaac cccttcatcc ttatatttct caattccatc ttctaacttt ctactaaact
     7501 catctatgct gtcaccatgg tttaatccta aagtttctac attttcctgt ttgcctacta
     7561 ttaattcagc actttctaac attgctttag ccatatttcc atgtgtggct ataattattc
     7621 ctgccatatg aatcatacct ttcttaacct tttttatatg gattattatt tagtactcta
     7681 atctaattat ctatattaat cattatctta ccaaagaaaa tatccctttt gtatactttt
     7741 tcaaaataag ctggtacttc ttctaaattt attctatgtg ttactaattt ttcaacattc
     7801 atatcaccct tttgcatatg atacaatcca gcactccatt cttttcctgg gaatggaaag
     7861 gagtttccaa accaagttcc ctttacagtt aattcacttc ttactatctt ttcaaattgc
     7921 tctctagtca aagctacatc cccatatggt acacctgcat acaatactgt acctcccttt
     7981 ttagctagca acagtacttg accacatgtc agtggagtac cagccgattc aataacaata
     8041 tctgcaccat ctccatcagt taaccttttt atttcttcta caatattctt ttcttttgca
     8101 tttatacaaa tatctgcccc taaccctttt gccaagtcta acttctcatc aaatacatcc
     8161 acagctatta cttttgtaga accaaatatt tttgcccatt gtattgaaaa taatcctatt
     8221 ggacctgtac caagtactac aacagtatct ccaactttag cttctgacct aaaaagacca
     8281 tgtcctgcta tacatactgg ttctagcgca gcggcagtct cataacttat ctcatctggt
     8341 atttttatta aatttctctc tttcaccttt gtatactctg caaaacaacc tccaagttct
     8401 ttatttccta ttattgctac attattacat cttgaataca atcctttttt acattcatta
     8461 cattcaaaac atggcatggc tggacaaaca gcaactctat ctcctatttt aaaactcctt
     8521 acttctttac caacctgtgc cacttctcca gaaaattcat gccctaaaat ttctccaacc
     8581 atatgtggac ctgtctttga atattttgat atatcagaac cacatattcc agctactttt
     8641 actttaatta ttacatcatc tttttctaat atttttggta catccacatc ctccactctt
     8701 gtgtctctta taccatagaa tctaactgac ttcactatta accaccccta ctttttattt
     8761 gagaatatat ccctattgtt tatatgttaa atatctaaag caactttcat gccaatatat
     8821 gtaagcattg tattcatgca ttttataaaa ttatcattaa atgtgtgtca aagtgtgtca
     8881 aaagtttctt atattaaaac ttatgtgtgt caatataaac gacactaaca ttttatatta
     8941 gttctcttat tataagtttt ataaaatgta ctttttttgt tatttttata aaattgttcg
     9001 gaaattcccc ttctatttgt gatataatat taaatataag gtatcaatat aaattttcat
     9061 gcgaatatca gaactttttt gacactaatg ccttattcaa tataataatt taactttttg
     9121 gaggttgttt atgaaaaaag tgtatcaagg aaagactaaa gatgtttttg aattagataa
     9181 tggaaattac ttacttaaat ttaaagacga tgtaactggt aaagatggag tatttgaccc
     9241 aggcgaaaat agtgtaggtc taagtataga tggaattggt agagctaatt tagagacatc
     9301 tgttaagttc tttgaaattc taaacaatgc tggaattaaa actcattatg taagtgctaa
     9361 tttagaagaa gcaactatgg aagttctacc agcaaaagtt tttggtaatg gattagaagt
     9421 tatttgtcgt tatagagctg ttggtagttt cttacgtcgt tatggttcat gtgttgaaga
     9481 aggtgctaaa ctagattgtt acgtagaagc aactttaaaa gatgatgacc gttgtgaccc
     9541 tcttataaca tctgaaggtt tagaagcttt aaacattatg actcaagctc aatttgattc
     9601 aatgaaaagc atgactcaaa aaatttctaa catagttcgt gatactatag ctgaaaaagg
     9661 tcttgagctt tatgatatta aatttgaatt tggattctac aatgatgaag taatcttaat
     9721 agatgaaata gcatctggaa atatgcgtgt ttataaagat ggtgtaatag ttgaccctat
     9781 ggatttaact gctcttttat tagataaata gtatatacat ataatttaca aatataataa
     9841 acttataaat aagataagct atgaagtaaa gactttttaa atgttgatta tttttaaaca
     9901 ttttctcgcc tttaatttca tagcttattt aaattaatat actctaatta gtagataata
     9961 gctttaaccc tacaattccc accacaataa aacctataca tgcaattctt gatatactaa
    10021 taggctcatt taaaatagcc atgcctacaa tagctgtacc gacggtacca attccagtcc
    10081 atattgcata tgaagttcca agtggaagat gttttagtgc taatgacaaa aaataaaaac
    10141 ttacaatcat tccaacaaca gtaagtatac ttggagttaa tttagaaaat ccatgtgaat
    10201 tttttagttg aaaagcccaa aacacttcaa acaaacctgc aacaaacaaa aataaccatt
    10261 tcataaattc atccctcttt tcaaatatgt ctcttatttt tccaataaaa taacctgaga
    10321 aatattataa aatatctccc aggtttttgt ccttccgtgt tcacaacaaa aactatgttg
    10381 tgggttttat ctcggaccag accaatcatt aataattgcg gaaccctata aaactctatt
    10441 aattattcta ttttatctat aataatacta tcaacatata taaaaaaagt caatatatgg
    10501 gttccatata taataaaaat aacttttata taccttttaa tattcttatt cacttctctc
    10561 catacccatt tgggtcaatc taagaatatc taatttttat ttaatatgtt ataataacat
    10621 aaaaatattg aaaggagtaa tttctatgaa tttctataaa attgcagtat gtcagatgat
    10681 tactacagaa aataaaattg aaaatatcaa tcatgctgta gatatggtaa cagaagctgc
    10741 catcaatgga gctaaaattg tagttttgcc agaaatgttt aactgtccgt atgaaaataa
    10801 atattttccc aaatttgctg aagaatatcc aggtgaaaca acaacgatat taagtaaatt
    10861 agctgagaaa catggaattt atctagtttc tggtagtatt cctgagttag aagatggaaa
    10921 aatctataat acttgctatg tatttgataa aaatggagat ctaattggaa aacatcgtaa
    10981 aatgcactta tttgacattg aagttacagg aaaagttagt tttaaagaat cagatactct
    11041 tacagctgga aatgatgtca ctgtaataga taccgaatat ggaaaagttg gtatagctat
    11101 ttgctatgat attcgtttcc ctgagttatc acgtttaatg gctcttaaag gtgctgaaat
    11161 cgttatctta cctgctgcat ttaatatgac tactggtccc gcccattggg agttatctat
    11221 aagaatgcgt gctttagata atcagatatt ctatgttggt gctgcacctg ctagaaatat
    11281 gaatgcttct tatatagctt ttggaaattc aagaatttca gacccttggg gaagaataat
    11341 tgctcaagct gatgaaaaag aatgtattat ttatgctgac attgatagag atttaattcc
    11401 tgacataaga caacagttac cacttcttaa gcacagaaga actgatttat atgaacttaa
    11461 tactttgaaa taaaacagaa cataacccca taaatcataa attaagtgtt aaaaaaattt
    11521 atggggttct cattaatttg atttaaaatt aatttcataa aaataatgct aaaattaatt
    11581 taattaaata atactaataa ttactaatga ttatgctaat tatcagcatt tactaattta
    11641 atcactatta gttatttctt ttattaaata tctttacttt tttacttatt atgtcttcta
    11701 gctttacatt tggattatgg tatttctttc tatttttagt cacatctttc tattgaatta
    11761 cttgcttaaa acaccaatgc acacatgcca gataatgttc acaattatgt agaaatcttg
    11821 ctctaccttc ttcaatgttg atattatctc tcctagttga tattatcttt cctaaaattt
    11881 cttttaatta aaaaataaca ttagttgata tatcaagtat attttaatca actgaaaaaa
    11941 acaataataa ttgatatatc aactaattaa tgtagattaa ttcattttta taatttatat
    12001 actttttaat taatctacct tatttaatta aaatccttcc tttctattta tccattttca
    12061 acttaaatta taagatttca tcagctatat ttttgcatac caataattat taaatatcaa
    12121 atatatattt tattaaaatt tctaataatt tcatccttga tttatttaat atataaaaat
    12181 atactaactt taatgattaa gttttgaaat ataactaaga atttgataat ttattgagat
    12241 ttttatacta aaatatacat actatacaaa cttaatttag aagggagcat tcttatgaac
    12301 aataaaatac tcgtcgtaga tgatgaggaa ggtataataa cactcttaaa agattacttt
    12361 gaaatgaata gttatgaggt ttacactgct caaagtggaa aagacgcatt aaaaaaaata
    12421 tccaaaaatc cagatatcat tctacttgat ataaacatgc ctgaaataga tggaattgaa
    12481 gtttgtaata gaattagaga ttatgtatca tgccctattc tatttcttac agctagaatt
    12541 gaaaatactg acaagataaa tggttttcgt gctggtgctg atgattatat tgtaaaacct
    12601 tttgatttag acgaacttgg agctagagta tctgcccatt taagacgtga acaaaggaag
    12661 tcaaatcaaa ctaaaattaa attttataat gatttaacaa tagattacga aaaaaggtta
    12721 atttgtatat ataataatca gatttcactt tcaaaaaagg aatttgatat agtagagctt
    12781 ctctctatga atcctggaca agtatttgat aaagaaaaaa tatatgatag agtctgggga
    12841 tacaatagca atggaaatag tgatgttata atggaacaca ttagaaaaat acgaatcaaa
    12901 ctatcaaaac atactcttga aaattatata gaaacagtct ggggagttgg ttataaatgg
    12961 ataaaataaa taatatgtca ttaaaaaaag ctttctttgt tcttacttta tcttcactaa
    13021 ttatagcatc agtgcttact actttcgcat acattttact taataatcta tataattcta
    13081 tacaagataa gtatttaaaa acacctataa atacaggtat tataaccata gttcaaaaca
    13141 atgtgaacca atttagtgat tatgataaaa cattacttaa tataatcaac atacttcagc
    13201 ttgtacttcc acttatattt tttataggac ttttattatt agctgatata attttttaca
    13261 aggtaaaatt aaaaacaccc atagaaatac tcaataaagg tgcaatggaa atatccaaca
    13321 acaatttaga cttttgctta gagtataata ataatgatga attaggtaat ctatgtaatg
    13381 cttttgaaaa aatgaggtct gaactaaata aaaacaacat aaagatgtgg actatgatta
    13441 atgatagaaa acaacttaat gctgcttttt ctcatgattt aagaaatccc ctaacagttc
    13501 taaaaggtta ctcaaactat ttaacaaaat acataccaac aggtaagctt agtgatgaga
    13561 agattttatc aaccacacaa cttatgtctg atcatattaa cagaattgaa tactatgtag
    13621 aaaatatgag taatgctcaa cgattagaag atttagttgt ttcaaaatct atgtcgaata
    13681 taaacaagtt tatagaaaac ttagatgaaa atatatctat cattgctaaa caagaaggaa
    13741 aatcttttac acttaaaagt caaataaata atataaatct attttttgat gaaaatatca
    13801 ttcttagagt cgtcgaaaat ataatatcga atgcttttag atatgctaga aataatgtat
    13861 ccatacttat atatcttgaa caagaactcc ttacctttgt aattgaagat gatggtatag
    13921 gatttagtaa ggaatctcta aaattagctt taagaccttt ctatagagat aagactttaa
    13981 atgacagcaa tgcacacttt ggtatgggtc tttatatctc aaaaatatta tgcgaaaaac
    14041 atggtggctc tatttctatt gaaaataatt ctactaacag tgctaaaatt actgctaaat
    14101 tctcaacaag aaattaaaat gattttgtaa gctttcactg ttcttatata aaatttgtta
    14161 gtttagaatt tataaaatgt atttcaattt acaaccaata tatatactat tttgtagaag
    14221 ttgtaagagt tgcttcaatt ataatatttt ggcaaaaggc atttgaaaca ataatagaaa
    14281 tatatattta aatatgtaga atagtatgaa attagaattt tggaggtgat tatattaaaa
    14341 gttttgctaa taatattaca ttctctcgta ttgtgtttgc attgctaatg cttagttcta
    14401 cattctgttc actgcctttc tggatatgtt atttttggtg tggaattagt gatatatttg
    14461 atggtcttat tgcccgaaag ttgagacaac aaagtggaat aggtgcaaag ttagatagta
    14521 ttgctgattt cattttttcg gttacaattt tggttactgt cggaaaaaat attgctcttc
    14581 ccatgtatct atggtggtgt attgttgcaa tagcattgtt acggttgatt agttacagta
    14641 ttggtttttt taagtatcgc acattttcat cgcttcatac tttgatgaat aaaatcactg
    14701 gaatttctat ctttgcgttt ccattactct atatttgctt tggtcttgat gttgcaggaa
    14761 ttatgatatg tatcgtggct tttctttctt cttttgaaga aatagcaatt atgataaaat
    14821 caaaagaatt aaatcgtgat ataaaaagta tatttatgtg aaaacttaga atttgtgaca
    14881 aaaataattt atataataat gaggaagtaa aacataaaaa attatccaca agtttatgtg
    14941 taaaatagtt ttaaagcaat agagttgtat tgtaaagcct ttagtgcata aattacattt
    15001 taaattaaaa atgatactga aactgcttat cagcactgcg aattatccgc aaatagtgaa
    15061 gactttttag atttaagcta aaagttggga aaaaattgag ttttaaaact tacactcttc
    15121 ttatatagaa aaggagagtg ttttttatga ttataaaagc aaaacaatta tcaaaaatat
    15181 atggttctaa taacaataaa gttatcgcac ttaataatgt aaatttagaa ataaactcag
    15241 gtgaatttgt ttctgtaatt ggaccttctg gaagtggaaa aagcacactt ttacatattt
    15301 taagtggatt agataatcct acctctggac aagtgttact tgatgataaa gatatatata
    15361 aacacactga aaaagaacta tctgcactta gaagaaaatc ctttggattc gtctttcaac
    15421 aatttaatct tttacctgtt ctgacagcat ctgaaaatat ttcaatgcct gtacttctag
    15481 ataaaaaaca acctgataaa gaatatttaa atgaaatctc atcattactt ggaattgcag
    15541 atagactcaa tcatcttccc catgaacttt caggtggtca acaacaaaga gttgcaattg
    15601 ctagagcact tattgcaaaa ccagatataa tatttgctga tgagcctaca ggaaacttgg
    15661 acagtaaaag tggcagtgaa gttatgaatc ttcttataaa aacttcaaaa cagtttggaa
    15721 agactttagt ggtaattact catgatgata gaattgcaaa acttgctgat agaaaaattt
    15781 caattattga tggtgttctt atggaggtga aatagaaatg aagaattacc tttcactttc
    15841 aataaaagaa ttaaaaagcc agaaacttat gactacattc atcattatag caatagtact
    15901 atcaactatt atgacaactg tggttggaca gtcaattggt atcctacaaa atttaagaat
    15961 tgaacaagcc cgttctttta acggtgatag acatgtatcc tttcaccaac ttactaaaaa
    16021 tcaagttgat gacataaaga aagatgatag agtttatcaa gctggtactt caataactct
    16081 tggcagtagt aaaataaagg attctggtat ctctgtactt gtaaaagagt atgataaaac
    16141 aggactttcc aactacccca aattaatgaa attaaaatct ggaaatttgc ctaaagataa
    16201 aaacgaaata gccttagatg aaaacacact aaagcttatg ggtataaaac caagactagg
    16261 agtgactata cctatgaatt tagatatttc acttttaaat gataccatac caccatataa
    16321 ttacacagct aactttaaat tgagtggcat tttagaggat gattatacag gatatgtaag
    16381 tggtatagta aatggtattg taggtaaagg tacatcagaa aatctattac ctaagagata
    16441 tattttatcc tctttggatt ttaaaataaa acagcaagaa aagtttcaag aaatagtaaa
    16501 tcaattagct aaaaaaataa atctttctca caattcaatt caatataatt ggatttactt
    16561 aaatgctctt aagatacagt ttgaaaaaga tgaaaatagt tctaatagtg atggtatatc
    16621 tatgattata ttggtatctt tatttgttgc cttattggtt ttactggcct ctggacttgt
    16681 aatctataat attttaaaaa tctctgttac aaagaaaatt aaagagtatg gatgtttaag
    16741 agcaatagga gctgaaccaa accagatata taagatagtt attttacaaa tcttaatttt
    16801 atgtactgtt gccataccta ttggagctgt aattggaatt atatcttcta aaggcataac
    16861 tggaatggtc actaatatct taaatccaga tatacttcta gcaaatgata ataaagaaat
    16921 tactgagctt atacataaaa atacaacagc atatatgttc ccattagtat taagcactaa
    16981 tgtatctttg attttttcat ttatttcagc attaccatca gcaatatatg cttcacatgt
    17041 ctctcccaaa attgctatgg ttggtagtac taccaaaatc aaaagaaaaa ttaaaagaga
    17101 aaaaacaata aaaaactttg aaagacatct agcatggcta aacttaaaaa gaaataaagg
    17161 aagaactata ataactatac tatcattatt tatgagtata acagtattcg ttgcactgag
    17221 tgagttctct aatgtattag atgtatctag gtcagtaagt aatttaaaag aaggagattt
    17281 ttccttaaca aatgaaatat ctggttttga taaatcaaca ctagataaaa taactaaaat
    17341 gaaaaacgtc aatcgcactt cctttataaa gtactctgaa tacaaacagg gggaaataga
    17401 tacagatata aattttgaaa atagtggtga gatgttaaaa atcattggaa ttgatgagca
    17461 aactttaaaa gacttaatgc cttctattac agattctata ctagaagact ttaaaaatgg
    17521 ttctatctgt tttataaaaa atccgattgc tatttctaca ccaggtgtaa aaactagaca
    17581 tacaaattta aaacctaaag atagtatcac aatcaacaaa aaacaactag atatatatag
    17641 tacagtagat aaaatgttct ttttacaagg taatggctgg ataaatggtg ttgatgttat
    17701 tgtatatgat tctgtttata acaccttgac aaataaaaac aagttcaacc agataaatat
    17761 ttatgctaaa gataaatcaa aattagaaca aataagattg tctattgaac agatttgtga
    17821 aaataatcct ggctctcatt ggatatcata tattgaatca gataaacaac ttaaagagag
    17881 ttttaaacaa atagaatttc tagcatgggc agttatatta tttgtgggat tgattggtac
    17941 tttaaacatc attaacacaa ctcatacaaa tataaatact aggactaatg agattggagt
    18001 taaaagagct attggtatga gtaatagtag cttatataaa atgtttttat gggaaggtgt
    18061 ttattatgga atttttgctg ctatatttgg ttcaattgct gggtatgcca gtgctattat
    18121 tataaacatg gcaactatag aaaagcttga tttcactaat ataccaatta cttcaatttt
    18181 acaagctact attatttctg tacttgcatg tattatagct actcttattc cgttaagaaa
    18241 agttaaaaag atgaatataa ttgactgtat agatatcaat ttataactat tttacagata
    18301 ataatataaa ttaaattatc aatgactgtc tctattttct ttcaaatcta actaataaat
    18361 ctttttaact ataatataag ctttaaaaaa ggcctatctc aaaatagaga taagcctttt
    18421 ttcattgtcg aaataatgaa aatatattta acttcacaaa aaaagagtgc ctcacgaatt
    18481 aaaaatttcg ctttgagaca ctccccttta atttaaaata tatagttaaa tgctatgcca
    18541 aaatttcaca catgctccac ctgattttga attttctatt ttaacagaac ctccaagctg
    18601 ttccactaat tgtttgacaa tgtaaagccc aagaccagaa tgtccacctt ttgtctgcct
    18661 agcttcatct cctcgataaa atttatcaag agcctttttt aaatctttag agctaaaccc
    18721 tctaccagaa tcacaaatct cataagaaat acaatttttt tcatccttta cagtaatact
    18781 aatattacca cctgatggag tgtattgcag actgttggat atgatattat caaaaattcg
    18841 tgtcaaccta tccacgtcga tttgaattgg ggattgtata ttcccctgca ttttcaatat
    18901 aagttcaact tccttttgat gagcctgtaa ttcatagtct tgcacctttt gcctcaaaaa
    18961 ttcaggtaaa tttataggaa caagatttaa ttgtatattt gacttttcta agtcagacgt
    19021 atattgcatc ttttggacaa gagcagcact tttttctgta ttttctctta tcactgtaag
    19081 atacctatga agtttttcat tgtcatctgt attattacca ataagtgcat ctgtatatcc
    19141 caaaataata gaaagaggag attttaaatc atgtgctaga gcttccacca tttcaacacg
    19201 ttcctgctcc atcttccact gtgcagataa agagcctttt aattcgtctt tcatttcaga
    19261 aaatgcacta caaagtttac cgagttcatt atctgaataa tagtcgattt caaaatcaag
    19321 gtccttttct tttatcttct tggacgcatc aatcaataga tgtaatggtt gattgatatt
    19381 ctttacaaag cgcttagaaa gccatctagt aaaacccaca atatatagaa atggagaaaa
    19441 cagagccatt ataataactg caaatacaaa tctccctcta atatttgcaa aggtgatttt
    19501 cacttggtag aatagaataa cagctccctc aatctttcca ttatcccctt tgattggaac
    19561 agtatggata taaccacctt tacgaacagt tttattgata aaattattaa ataattcttc
    19621 ttttgtttta aatagttttt tggggttagt accatataaa atattgccat tattatccac
    19681 aacttgatat agcatatcat ccccacgaat cgttcttttt aaaccttctt cattcgattg
    19741 tgataacaaa gttatgtttt tttcattgat gtatttttca attctaggaa cttgtcgctc
    19801 ataatagttt ggtggataga tatccttatt taaggaatga atatacaaat agagagcaaa
    19861 tacataagta atcactgtgg caactatact ggctattata ataaaaataa aagtatgtct
    19921 aaattgggta ataagggatt gatttttcat ttaataacct ctctctcttt acattttatt
    19981 ccacttatac ccaatacccc aaactgtgga aatatattct ttttctggtg tcacagcaga
    20041 aaacttagct cgtatttttt ttactcgttc aacaacagtt gaggaatcac cttcagaatc
    20101 acacccccat actttttcat agatttgttc tcttgagaaa acttgtcctg catggagtgc
    20161 tagtaattca acaatatcat actctatttt tgttaaatca atattcttac catcaatttt
    20221 aattgcacgt tccttcatat ataagcataa cttcccaaaa tacaaagtag atctcttgtt
    20281 ctcttcattg atatactgtg aacgcttttc cctacgcaga ttagcttcaa tccttgccat
    20341 aagttcacgc agtccaaatg gctttgttac ataatcatcc cctccaaagg tcaacccttt
    20401 gattttgtcg gtttctgatt gctttgcact taaaaatata attgggcata aaacatcatc
    20461 tctaattgcc tgacatacct caaatccatt cattttaggc atcataatat ccagtataat
    20521 aaggtcaggc tcctgttttg ataactctat acctgcctga ccatcataag ctatcaacac
    20581 ttcatgtcct tttgccttca attcatcctc aagtagcatt actaggtcca tttcatcatc
    20641 aataatcaat attttactca atataacacc acctttctct tatgggaagg tcagtattaa
    20701 aacaatattc gtctactaat aacttttcct tccctcccac attttaaacc aaataacgcc
    20761 tcctatcaag aatataatca aacctattgc tactactata agctctatac tagctgtttg
    20821 catcacttta gagtaaaatg cctcagttga aatagttcca gcttctttaa taaaataaat
    20881 tcctggaagc atacctagtt ttactggcca tgtccatgga acaaatgccc atactttttc
    20941 accaacgcta gttaatccaa gtattgctgc catcaaaatt ccaccgatac taataccaat
    21001 agatgcaccc ataccccatg caaaactcac ccaaagatga atagctaata gtggaagtgt
    21061 cccaatcacc acaagtcctg ctgctgacag gaataaccat attgttgctc cagatggcac
    21121 tgcaatactc attcctatgc aaagtatcaa cgtagcaata aatgtgcata tagttaggca
    21181 aaacagaaga aaaagaaatt ttcccagata taatctaaca cgagaaatac ctacacataa
    21241 aaaaccatta aaatttccag caagctcttc ctcctgcact ataaatcctg ctaaaatacc
    21301 tactccaata ggaatgatga atacagtcca tactgtaaaa aatccttcaa aagcaaattc
    21361 ttgtgtactt ccagatttag ttgtgagata aaaaaccaca cataatgaaa aaataatagg
    21421 catacaaaga gtaagccact ggacagctgt cctctttgct cgaagccatt ctgatgataa
    21481 tagctttatc atttgtcatc cctcctattg aaccaagctg cagtaagtgc tgttaatact
    21541 ataaacacaa ccaaagaaac aacaatccca ataggaatca ctgaagtatt caaaagtggg
    21601 tctccagctt ctaatatagt accgttagga tgtatgttga tgattgggca taccattcta
    21661 actgcccaac tccaaggtac tgcaatccaa aatggttttg tcgcagcaag gacaccaaat
    21721 atcataccta aagctccaac tcccatactt aggaacatac ctttccatgt agctagccat
    21781 agctgaagtg gaagtatagc aagagaaaca acccagcata caatacttgc ccctataatc
    21841 tgtccaaaag gaactggacc agctttcaat attaaaccag ttataattgt tacgactatt
    21901 aaaactagcg ttgaaataaa actgtagact gccatagcta taactttatt aatccaaagt
    21961 gtcataggag acacattgtg tgtacgtaaa gcacgataat ttccagcttt tttttcctgg
    22021 aaagctacca aagtagcaaa caatgcaaat ccaataggca gaaataaaaa tgaccaccag
    22081 ttaaaaatta atgctaaaag attttgccac gcccaagaag ttgtttgaga taatggattt
    22141 tgcatgagtg ttgattgcat tataaatgca tatgctgcaa aagacactgg gaaaaaaaca
    22201 ataagtttac ccataaatgt tcttttatac tttaaaagtt ctgattgtaa agcattcatc
    22261 tgttttgtcc tcctttaaga ataacatctg taaaaaattc ttctagattt tcattagggt
    22321 caggcattcc ttgaaataat agtcgtcctc catttataat tcctatatta tctacaactt
    22381 gagcaacctc tgatagaata tggctagaaa gaattacagt tatacctttt tttggaaaag
    22441 aagcaatcaa ttcacgcaat tcttgaatgc caaaggggtc aagaccattg gttggttcat
    22501 ctagtattaa caactctggg tcactcaaaa gtgcaatagc tattcctaac ctttgtttca
    22561 tacccataga aaattgtgaa gctctctttt tacctgtatt tttcaaattt actatttcca
    22621 acacttcata aattttatct ttaggtattc ccaatatttt tgtatgtact aacaaatttt
    22681 cctctgctgt aaggtttcca tacaatgcag gggattctat taaagaacct atttttgcaa
    22741 gagattctcg tttccaaggc tttctatcaa aaataatacg accatttgtt ggacgaagaa
    22801 gaccaacaag cattttaagt gttgtggact ttcctgctcc atttggtcct aaaagtccat
    22861 atatactatt tcgttcaatt tgtagagaaa cattgttaac tgccatttgt tctccatatc
    22921 tttttgataa gttttttgtt tcaagaatta aatctttcat attaatttct cccttcttgt
    22981 aataccttaa atctgttact aagagaatac taacatgaaa aaataacaat tctataacac
    23041 ctactaattt taataaaatt taaaataaaa aatagagtta ccaattttat tttggcaact
    23101 ctatttaagt ttatgtttta cagttatatt agatttaaac ttagtttcat tatcacacta
    23161 acttcaaatt tactctataa tctttaaatc aaacactaat ttattaatca aacactaatc
    23221 tattaattta tatttcttta gacatctaat atagtttgct actaaataat aattatttat
    23281 atcatattta tctaatcctt taaaagaagt tatttcatca ttaagctcat cactaccttc
    23341 tacaaaaaca caacctgttt caaattccat acctacaata atcttacagc cactataaat
    23401 ttcctcttga gtatcgtaca atttttttgc atttccttca tttggaattg taaatacaat
    23461 aggttttaat tctttatcac tggaaatctt ttgtgaaaaa ggcttgttta acttaatatt
    23521 attgataact acatgtttaa attcctctga agtttcttct actattacat attttcgctt
    23581 taaaaactct attatttcta aaacagactt agaatttact tttaaaatac ttttatattt
    23641 ttcatataaa gatttccact gttcaatttt ttcctgtggt atttcttgga tatgtgtact
    23701 tattttttct tgagatattt ttttcaatta aactctcctt tcaatactta aatatcctta
    23761 tgaatctcac atgactaaag ttacaaggtt tctacttaat agaattttgc atacttaaat
    23821 atgtcttatt aattctctac aggatatctc tgtaattcct acgattctta cataagttac
    23881 ttattttaaa ttgttattag ttagattcta aaaattattt attttatcac taatataata
    23941 ctcttaaaaa ctttacaaat caatttaaat ttgctacctt ttatttataa caacttatag
    24001 tacatttctc ctatgctttt caatatatta cttttaaaag gaggttttca ttatgatttt
    24061 aaatagagct gagcttttcc gaggatattc tttaaataga tttaacgaga tatgcaatat
    24121 attatcagta aataaaatta aatataagta taaagtgaaa aataatgctt actctaaaaa
    24181 accttttttt aatgaaataa cacttggcaa tttaggtcaa aaggaagatt tctcttatga
    24241 gtacttaatt tatgttcata aagacgatta tgaacaggca gagtctctaa taaattctaa
    24301 gttgcgatag attatttata aaacatgaca ttctgttgtc atgttttata tgttattata
    24361 ctttcaaata tgctactata ttttcaaaat tgtgtgcttt aaaactagct ttttatagta
    24421 atttaaagct taaaactaag gagactcgtt atatgaaaat aaatataaaa tcaaagttaa
    24481 gtgaatttat taaacagaac aatctttttg atgacagcag aataatatcc taccttccta
    24541 atataacaat agaaacagac aaaataaaaa ctataatgat taatgaggtt gtcccaacta
    24601 acaccaatga cgatttttat agtgtagata aagatgctga ttatttaaaa actactattc
    24661 ctttatttga cagtgcagga ataaaagtat ctaacataaa tgatatccta gatatgggta
    24721 tctatataac taatgcagta aaacttccta aatcagaata tacaataact cgtgatacaa
    24781 ttaaattaca tatgcctatt ttagaagaag aaattaaatt atttaaaaat ctagaggtag
    24841 taatgttaat gggagatgtt gcaaaaaaat cttttaatat gattactaaa aagcatataa
    24901 aaaagaatgt catcccttcc atttcaacat ataaacttcg taataatgaa ctttattatg
    24961 ataatttaag agtatttcca tcatatatta tgactggtgg aaacatactg attgaaaaat
    25021 caaaatttga aatggcatca gaagatataa aaaaaatgtt cgagattata aacggttgat
    25081 attacaaaat aataaaaact aatataaaat aaaaagtgcc tcaaaaactt ctatttatga
    25141 ggcactttta ttttatatta gtgtaactat atactattaa cataatttat tatttatatt
    25201 gttcttttta atctctattc catttagtct aggtaacatt actctttaca agattacttt
    25261 atatttcttt tatatctcta acgtttttat ttaataaaac aattattaat acaagtcaaa
    25321 tatatctatt tatctaaaaa tatatctttt acagtaatat ctggatggtg atacttcttc
    25381 ctattcgtta aaaaagattt ttttacatta atagcctctt ttggacacca gtgaaaacaa
    25441 gctaggcatc tttcacactc attaccccac tttggctttt tatcaactat acttatattc
    25501 tctacaggac aaaccctttt acatgtccca catccattac atttattttc tgcaaaaaat
    25561 ttagtagttg caatttgcat attcttacct actaaacgaa gtacaacact atctatatgt
    25621 gactttaaat tgttttttcc ttctatattt ccaatctcca agttattgat acattttgca
    25681 atctcagcta ccctattagt ctgatttttc aatctttctt cttcaacatc tggaggtgtt
    25741 atcaaagcat ttccaggcat attgattaaa aaaccagcag ataatttttt cccccttttt
    25801 ttaagtaact tatctatagt aaataaacta tgtccagcta ccccattaca agtggcaatg
    25861 gcatatatat gagtattaat attaaaattt aatttctcta caaaagactt tactatatca
    25921 ggaacatcag caaaataaac aggaaaaaca attaccaata tatcttcatt tatgtctata
    25981 ttattttctt ttctatgtat agctaagggt ataacttctt tacttccatt taacgtttct
    26041 tttaaaatat ttgaaactac tagcgaattt cctgttccag aaaaataata aatcttacta
    26101 ttcattctta tccctctttc tatatttcta catcatcaat agttaaaaag tctcttaaaa
    26161 taggatttat atttactttc caattctatc caaaatatca gtaaacaaag gcaattcttc
    26221 atcagagata gatttaaatg tctctgttgc atatatactt gcaatttcat ttaatggttc
    26281 ttctaattct ctacctaaat ctgttaggaa tatttgaaac ttacgtctat ctttaacatc
    26341 tactttacgg acaattaatc ccttattttt cataacatct aagattcttg tcgtattaga
    26401 tttatcctta catgattttt cacataaatc tatctgagaa attccatctt gctcccatag
    26461 aaaccttaat aacgcataat ggtcagttgt tatatcatat ccattttgtt taaacatctt
    26521 ttttaaatca tcttttactt ttaacgaagt acttactaac ttagttgtag cttcatatag
    26581 tttctcaaaa tctttcattt tacctccatt taaataatcc cttgctcctc ccatctatca
    26641 attattccct tatattgctc aatatcttta aaagccattg gctttaaaac agcatttata
    26701 gcaataaaat tatagatttg agaaagaaca ggtggatttt tcttttcctc tatgcaataa
    26761 ataaattttt tagatacctt ttgtatcttt gattctactt tttcagttat aggattttga
    26821 ttaaatccag tttttataga taaactacca caaacataac ctcccgaatc taagaccatg
    26881 gattttataa aagaaattgc ttttgaacca cgtgcatttt catatgtagt aactgctata
    26941 catggcttac gatacaataa tctttcaagc atcatatgtg ctctatctgt aaacaccttg
    27001 aaaagtccag ttacactact tccataagtt gggctaccaa atataacacc atcactctta
    27061 gtaattatat catgaatata ctctacttta tcattttgat tgatacactt gcccatttta
    27121 taacaattta aacaaccaat acaatatgat ggatttacct cacttaaatc aaaataatta
    27181 atttttacat ctggtattaa tctttctata tctttataca agtaagttaa aacttttgat
    27241 gtagctccat tttttctagg gcttccattt ataactgtaa ttatcatttc tatatctcct
    27301 ttttagttgt tatatcaaca ataagtatat caactatatt tttagctgtc aatataaacc
    27361 atttatttaa agccatactt acacagctta aataaaagtt ttatttaact acatgtgctt
    27421 atttaatcaa ctataaatga attattttta ataattgaca aactaaatta atgataatat
    27481 actttatgta ttacaaatgt aagtagaagg aggtatagta tgaaaaagtt accacatatt
    27541 tcagaagcag aatatcaagt tatgaaaatt atttggaaat atgctcctat cagcactact
    27601 gaagtaattg aaaagttggt agaaacaagt acatggagtc ctaaaacaat tcaaacaatg
    27661 ttattgagat tagttaaaaa aggagcttta acatatgaaa aaaatagcag agtattcgtt
    27721 tatactccac ttgttaaaga agaagaatac gtagctagag aaagtagttc ttttttaaat
    27781 cgtttttata atggtactct taattctatg gtactaaact ttttagaaaa tgataaacta
    27841 tctgaagatg atattgagga actgagagaa atcttaaata aaaggacgac taagggggat
    27901 aaataaatat gtatgcccca ttctttatac gatttttact cagtacatta accttatcaa
    27961 tattaattgt tgtaatttta cttgccaaaa aagtatttaa aaaacatatt tctgcaaagt
    28021 accaatacaa tattggattt atattgctta taatgttaat aattccattt gtccctctta
    28081 aatatattaa tcttggaaat gtatttaact atttatatac ttttaatcaa cttggaagca
    28141 gtactaatag gacttctatg ataaaaaata gtccaaattc tgtaattaat aactcaaatg
    28201 cattaaacga tttttcagta tccctaaacc aagttaattt tgatagttta aatattttat
    28261 tactaatatc atggataatt ggaattttaa tcatgatagc tattactatt cattgcaaca
    28321 ttaaaataaa aaatatgaaa aaatcaatac aaattttaag agatgatgag atagtattta
    28381 tatttgaaaa gtgtaaaaaa gatattggta taaataagga ttttatacta tgcaaatcac
    28441 ctattataaa tacacctatt acatttggat actttaaacc acacattata ttaccagata
    28501 agtctatatc taaattatct ttaaaagata taaaatatat cttacttcat gaattacaac
    28561 actttaaaaa taaagatata ctgataaatt atataatgtg cttccttcaa atattatatt
    28621 ggtttaatcc tcttgtatgg tatgcattta aagaaatgcg tatagaccgt gaaattgcat
    28681 gtgatatttc agttttaaaa aagcttgata aagatagtca tatagaatat ggacaaactc
    28741 taataaactt tgtggataat atttcaagac catcaaatct tacacttaca tcagatattg
    28801 gtgggtcaaa aaaacaaata aaaaagcgac tattgaagat aatggatttt cataatgaat
    28861 caaatacgtt aaaattcaaa agcattttaa tttttacatt gatagcttta attgtatttg
    28921 gaaatattcc caaactatct attatggcag atatcaacga aaaatataga cctacaaatg
    28981 aacaaactgt gtacgaggac ttaagtcagt attttaaagg ttttgatgga agttttgtta
    29041 tgtatgattt aaaatccaag caatatcata tttacaataa agaaaaaagt aaaacaagaa
    29101 tttctccaaa ttctacttat aagatttata gtgccttatt gggattggaa aatgggataa
    29161 taacaagaaa taattcacat atcccttggg atggaaagca tcattctaat agttcttgga
    29221 atgaagacca agacttattt tctgctatgg aaaactccgt aaactggtac tttcagactc
    29281 tagataaaaa aacagggcta aaaaacatac aaacttatct taggcaaatt ggatatggca
    29341 attatgatgt ttcaggtggt atctcaaact tttggctaga atcttcatta aaaatatcac
    29401 ctattgaaca ggtagaatta cttgaaagtt tttatacaaa taagtttaaa tttgaagata
    29461 aaaatataga aacagtaaaa gattcattgt taatatcaaa aaaggatggg gtatcacttt
    29521 ttggtaaaac aggcactgcc aatataaatg gaaaagatgt aaatggttgg tttataggtt
    29581 atgtggaaaa aaatgaaaat acttatttct ttgctacaaa tattcaaagc aaagattatt
    29641 ctaatggtag ttcagcatct aagataacat tatccatatt aaatgacaaa aaaatctata
    29701 atccttaata tatttactgt acattctaaa aaattcacat aattttcata ttaattatca
    29761 attaaattca tatacaaggc ttattatata aacatagaag atagtaaaac tagcttaaaa
    29821 acataatata ataccctata caaatagtgg caactctccc tcacatcctc aattgttgcc
    29881 actatttaat tttttgtatg aagttaaata tattttcatc atttcaacaa tttgggtgca
    29941 atacaatctc tattttgaaa caacctcttt aattgtttta gagtttatga attatttctc
    30001 atactttaaa aagattgaat tactcttgat aatcttcttt tgtagtcatt acatatcacc
    30061 tactactcaa cacatattct ttgacctatt tttacatcct tgtttatatc caaaatattt
    30121 accttcttac catctggaaa caataccatt gtcaaagtag actttcctaa ttcgtgtatt
    30181 ctctttaaat caacattaac aagaacatct ccctgtttaa ccatatctcc ttgtttaaca
    30241 gcaacatcaa agccatctcc atttaatgca actgtatcaa ttccaacatg aattaatact
    30301 tctccattag ttcctttaat cccaaatgca tgtccacttg aaaccactgt ttctaattta
    30361 cctgaaatag gagaaacaat ttttccatct ataatatcaa tagcaaaacc atcacctaac
    30421 atttttttag aaaatgtttc atctggtaca ttttctaatg caacaatttt ccccttagct
    30481 ggagacacaa agttttcatt attttcatta aacactaatt cttcgtcttc atcttcattt
    30541 atagcttctt taggcactcc aaataaacat gttacaataa agcagaatgc aaccacaaat
    30601 attgatacta ataagtatgt gattaaatta tatccatcat agatatacat taaataagaa
    30661 ggtaaaactg ctaatccata tgaattagat tgaatatgta aaattgataa tattgctgct
    30721 cctaaacctg aagatgcaca cataataatc aaaggcttta aattatatcg aagctgaatc
    30781 ccaaataaaa caggctcact tataccaaaa agttgagata gcattgctcc aaccgcagtt
    30841 tgtttaactt gattattttt agattttttc ataaatgcta gacatgttcc aatattcgca
    30901 aatccataca ttgcacaaag agtaataagg gcattaaatc ctgtatttgc taatagtgat
    30961 gtttcaatca ttacataagt atgatgtaag ccagtaataa cagctaatgg atatgtaaat
    31021 ccaataataa atcctccaat tcctaaaggc aaatcaatca ataagctgat gatatcaacc
    31081 atttttaatt ctattgtatg cattataggg cctacaccta acaaaataac taacattgtt
    31141 attagcataa caaaaaatgg tgtgaaaata aggtctaata cattaggcat atgtttacgg
    31201 aaccattttt caagattagc tccaataaat gctgtaacaa tagctgttaa aacacttcct
    31261 tgacaaccta caataggaat aaatccaaat gccataattg cttcaatttc atttgatggg
    31321 tcagcaacag aatatgcatt aggaagtatt ggggaaacta acataagtcc aataacaagt
    31381 ccaataacag gtgttcctcc aaatacttta aatgctgacc atacaataat tgctggtaaa
    31441 aaagcaaatg ctgtttctgt aagaactgaa acaagtgtct gaatatacaa tggaatattt
    31501 gcagaagaca ttcctaataa tccaagtaca ttatcattaa acaaacaacc ctttaatccc
    31561 aagaataatc ctgttgctgc aataactgga ataataggaa caaatatatc tgctagagtt
    31621 ctcataactt tcttaaatcc agtttcatta tttttaacta attcatcttg ttcttttttt
    31681 gataaagttt ttaatcccat tttttcaact tctgcataaa ctttattaac tattcctgtt
    31741 cctaaaataa tttgatactg tccagaagta aagaaaaccc ctttaacctc atcaactttt
    31801 tcaactttct tatcattaat aatttctcta tctttaacca tcactcttaa tcttgtggca
    31861 caatgtgtaa tagaaataat attatcttca ccaataattt taataagctc atttgctatt
    31921 ttattatatt tattcatttt tctacctcgc tttcaataat actgcatgaa atggtttcaa
    31981 acacactgtt ttatttaata gatttatatc atctaaattt tggaatacaa tatcatattt
    32041 ttcttctact cttatttcta caggtttatc agaaaaatta taataacaat caataactac
    32101 caaatctaat tgccttctat acgcaataac atcttcactt tctatatcaa taggttctat
    32161 tgaaccataa atcaaacaat cagaatactc actatcttgt ctcaacttta tcatcttttt
    32221 ataaaattct aaaatactct ctgaattgtt aatctgactc tgtgcattaa tatctttata
    32281 attttcaata acctttaacc atggtgttgt atctgaaaaa cctgcatttt ctttatctgc
    32341 ccatggaaat ggcgttcttg cattatctcg gcttcttaaa ttcacaaatt ctaacgcttc
    32401 ttcttctgag taaccttcat ctattgaacg atagtattgg tcaatgctag ataaatcatt
    32461 aaaatcattt atggtatctc ttttaaaatt tgtcattcct aattcctgcc cctgataaat
    32521 aaatggggtt cctcttaaaa agaaatacat tgctcccaac atttttactg catcatcatt
    32581 cctttcgtat tgcaaaagat actttgttgt agctcttggt tggtcatgat tttcaataaa
    32641 attagctgcc catccatgtt cctgaacata catttgacta tctaaaatgc attttcttaa
    32701 atctggaatt gtccatgaaa ttcttttaaa ccactcacta ccagaagcaa catctaagtc
    32761 agcatgttta aagtcaaaga ccattgaaaa gaaaccatct tctccaataa aatcacctag
    32821 ctggtcatag ctaatacctg ctgcttcagc aacagtcata caatcatatt ttttaaacgt
    32881 attttctttt aattcataaa gcattttttc tattccaggc tgatttctaa ctgtttttgt
    32941 acatttaaca agaccatcaa caccatcact ttctaaactt tgaaaactta aattcttttt
    33001 gataaatgta atagcatcaa ctctaaatcc tgccactccc atttgagacc aggtattaat
    33061 catttggtaa agttcacttc ttaatattgg attttcccaa ttaaggtcag gttgtttttt
    33121 accaaaagaa tgaaaataat attcgtctct attctctacc ttttcccaaa cacttccacc
    33181 aaaaacagac ctccagttat ttggtaaatc gtttcctttt ttaaaaatat aataatcatg
    33241 ataaggactt tctggatttt ttaatgcttc ttgaaaccaa ggatgttcat cacttgtatg
    33301 attaagaact aaatctaata taattttgat tcctctatct ttactttctt taattaactc
    33361 ttttaaatct tccatacttc caaattcact tgcaatatcc aaataatcac taatatcata
    33421 cccattatcg tccataggtg atttaaaaat tggacataac cacaatgatg taatacctaa
    33481 atcttttaaa taatctaaac gagaaataat tccctgtaaa tctccaattc catcattatt
    33541 actatcttga aagcttcttg gataaatttg ataaacgatt tctttttgcc accatttctt
    33601 ttccataaat tactcctttt tatatgatat ttcttctttt taattcttta taaattccat
    33661 tatcgaatat gtcctcacat atagatgtcg ctatatcttt aagttgttga tgactatttt
    33721 tcattgcaat tgtaacgtct gatgcttgaa acatgacaat gtcattttga ccatcaccaa
    33781 aacatatggt ttctttttga gttactccta atctttcttg taatctctta attgctttgc
    33841 ccttatgaaa atctttttga ataatttcat aatactgact agaaatatct ctctgtgcta
    33901 attccatttt atcttgtagt atatctttca cttcgtcaaa taccttttca tttgaccata
    33961 aacaaatttt atgtatatct tgtgacttat actcttcaat gttattttca tatgttattt
    34021 tttcttggat atgttgttta tttatacaag aattagttcc tttcaactga ttcattgttt
    34081 caaatatttc tttggctttt tgattcatga aaactttttc ctgactctca atcgaaaaag
    34141 caacttctct cttttttaat aaacaaacaa cttcctttat caatctttga ttaaaagatt
    34201 gattataaag taattcacca tgatactgaa tgtaattacc tcctcctgca atatatccat
    34261 caactcctaa tgataaaaca tcatcttgta ttgtacccat acttcttcca gtacaaataa
    34321 caacactgca atgattcttt tgacataaac gtatagcatg ctttgcagat tctgggattc
    34381 catatacctc atctctaagc gtaccatcta tatcaagtat taataatttg tacaatttca
    34441 tcttcctttc ttactatcaa aatcataata gcattcaaaa aaaaagatat caatattttg
    34501 atatctttta aaaaatatgt tcatttttag cacaaatttt cattttcggg gaatatgttc
    34561 actttctaaa tacatcttgt atttaatata aagcagttca attaaaataa aataaggtgt
    34621 tgttacatcg tagtccagtt gtttatctac agaaatagat atagattgaa tatacaggtt
    34681 ttcatcacat aatcttgcta aaggattact tatcattttt gtaatagaaa ccatataaat
    34741 tcctttcatt ctcatttctt tagcaaaatc aataattgta gatgcatctc cattcaatga
    34801 aataaagaaa atcatatcat ctgtttttat aaaatgatta agtgcctgaa tcatatcata
    34861 accataaaca tcatatataa ttttccctgt tggtaagaaa atccttttca tctctttagc
    34921 aactctttcc tgagaataac cttctccaaa gacgattata cgatttgcct ttttcattct
    34981 ttcaaacata atcgaacaat ccttcttctc tatatcatct atcaccttat tataacaatc
    35041 cattaattgg tgtttacttt gatttttata ttctacttct gtttcattta agcgtataat
    35101 aactcttaat tcactatatc caggtaattg tagtttttga gcaaaacgag aaagtgcact
    35161 tgtagatata tggtatttgt ctgcaaattc atctatagaa agtttaatac aatcttcttt
    35221 atgattaaga atacactcac agatatactt atcatttgct gtaaatgaat tataatattt
    35281 attgaaaagt ccttcaattt tcattctttt ctccttctat actctatgta attcatatga
    35341 agcaaatcta atagagcata aaatgctcct acgacttcat aagatatagc ttgtaatgta
    35401 tcaagttttt gcgtttcaac atacagatta tactcacaaa gtgttgcaat tgtattatta
    35461 tcaagcctag ttaaagaaat cgtatgtata tgattgttga taaattttgc aatttcaatt
    35521 cctgcttttg tttctccaga caaagaaatg ataataaata aatcactttt ttgaaatgat
    35581 tctctcataa attcaatttc acctatatca aataagtcaa taacacattt acctactgaa
    35641 agaaatattc tctttatttc ttgagctaaa cttttctgtt cattacctgt cccataaata
    35701 taaattgttt ctgcatcata tattatttta caaatatctt gaaatgatat tttttgtaat
    35761 tcattcatta atagtcgata attctcgcaa acatcatgaa aattattatc attattaaca
    35821 aattctagtt gattattttt aagtaaatac tttaaatcag agaatgaatc taatccaatt
    35881 tttctacaaa gccttaataa agtagctcta gaaacattac attcatttgc aattttttca
    35941 cacgaaaaat tacggtattc tctttgacaa atcaatattt gtttaataat aattttatca
    36001 ttttcattta aattatcata attttggtta actaacgatt ctaatctcat tttttccact
    36061 ccctaaatat tattttaata tacattagtt gctttttcta gggaagagtt ttaaataata
    36121 aggataaaat aatcatttga ttttattttt attaaaataa aaataacctg ctaaaagcag
    36181 gcaccaaaaa gtacttatcc tttcgaacat gtactttaga tattgctttc ttcagaagct
    36241 tcatctcttc atactctaaa atagagtttt ttctaactca aaagtgtttt ccatggtaga
    36301 aattacttta attcatctgc catttacttt ttatcttatt taataattac tattacttga
    36361 atatttactt ctttaagtaa atttcatagt taacaaagct aaaactatta ttatagatgt
    36421 taaaatacaa aattgtaagt attgttataa atatgcttac agctacaaat atacatgata
    36481 tattaaaaag aagctgtaaa ttattatcat acatacaagc aactatgcct ctattaatcc
    36541 atgttaattt ttattattta atacaaggag ttccatgaga catacatatc cattcatatt
    36601 ttaaattatc caattcgctt atagatttca tcatcttttt ataatcccaa ttccatggat
    36661 taggataagg aactatattt ccattcttat ttttgactaa atcacctgca aataatacat
    36721 cttcaaaaat catgcagaca tgccctggag tatgaccagg agtatggata atttttatat
    36781 tcccaatctg catattctct ccataaggtt caacatcctt aatgagcctt ctggaaattg
    36841 cctttccaat aaacttctta aacccaggtc tatccttctc tcctataata aaaggtatat
    36901 cctctacatg agcccatact tttgctcctg ttttttcttt caataattta atattagata
    36961 tatggtcaac atcatgatga gttaataaaa tatgcttaat atctgtaagt ttaatgccaa
    37021 gtgtttttaa ttctttaatt atattttccc ccataaaagg aagacctgtg tctataagaa
    37081 taatttcttt atcaaacaca ataaaacaat ttgagccacg agtactatct aacattaata
    37141 cattttcttt tatcttcata aataaattcc ccttatttgg tattttacct atataattaa
    37201 ttaataaagt tataaatagt tataatactt gatattaatt ttatttttta ttaaagtata
    37261 ctataggtat acaagtatta tatttacata agtataccat cagtatactt ttttatcaat
    37321 agaaaggaat aatttatatg tcagaattat caaaaagaga taaagaaaaa atacaaagag
    37381 aaaatgagat tattgataag gcagaaaaat tattttgtct taatggattt gataatacaa
    37441 ctatgaatga attagcaaaa gaagttgaat atactaaacg caccatatac aagtactttt
    37501 catgtaaaga agatttattc tttgctgttg tcttaagagg atataaaaga ctttgggata
    37561 atgttaaaat agaaagtgca aaaggcaaaa cagggtttga aaaaataaaa ctttcatact
    37621 ttgcttttca taaattttac tctgtagaac cttctctatt atgccttatg ggaatgattg
    37681 gtattgtaaa ctctgaaaaa tcggatactg atatgctgtt taaagaaaag tttttttctt
    37741 ttaataaatt tatgtttgat gaaatacaag gaatgtttga aattggaaaa aatgatagaa
    37801 gtattaggca tgatattgaa atacctactc ttatgtattc atcaatattt acacttacag
    37861 gattttttaa tttactatct gtaacaggaa aatcatacct gaacaacttt aatatagatg
    37921 aggaaaaatt tattgaaaca actcttgctc ttttaataga ttcaattaaa gcataaacct
    37981 aagtttataa attaaagttt atatacttaa atgataattt tttctatctc taatataaaa
    38041 aatattaaac ataaaactaa taacttagtt aatggaataa ctaaattact gaaaggatta
    38101 aaagtaaatg gctaaaatac ttcttttaga agatgatgat acaattacat ttggaataaa
    38161 aacttccctt gaaaagaaaa atcacactgt atgttgttat aatacgattg ctgaagctaa
    38221 aaaaaatttt gataaaacta ttgatttaat tctgcttgat ttaaatctac ctgatggtat
    38281 tggatacgag ttttgccaat atgttaaaag tatagaagat actccagtga tatttttgac
    38341 agtccgtgat gatgaaaaag acattatacg tggattagat atgggtgcag atgactatgt
    38401 ggttaaaccg tttttgctct cagtacttca atccagaatt aatgcagttc ttagaagaac
    38461 tcattcaaat actaacaata ctattacatg tgaaaatata agcttgaata aggttgaagt
    38521 caaagcatat ttagataatg ttgaagtacc tttgacagca ggagaatata aacttcttct
    38581 aagtcttatg gaaaataaaa atagagctat gactcgtaca aagttactag aaatgctctg
    38641 ggatgtagat ggtaatttcg taaatgataa cactcttact gttacaataa aacgtcttag
    38701 agaaaaatta aaaaatccac cttgtataaa aacattaaga ggcataggat atagaatgga
    38761 ggacaactag tgaaaactcc aagaaatatc aacagtacag ttgtttttat aatattctgc
    38821 ttaattgtaa cttttttatt gagtgtaatt ctaacaacta taacttcttt taatgaatac
    38881 aatgtactgt ctaaggctct tggtgcatca tatgagtaca atcctaagtc tacagaaagt
    38941 atactaaaat cactgaaaaa ttctagtgat aaggatttta aaacaggaaa tgaaatttta
    39001 tcaaaacatg gatattctaa aagtacattt tggagtaaaa acttttttta ttttctagtg
    39061 atatcgtttg gtataatttc aacaatggct acagttgtat atataatcaa acatagaaca
    39121 aataagcaaa aactgagtag aataaacaat cttactcaat acttagaaga agtgaattta
    39181 ggaaaagagt ctgtactttt acgatgtgaa gatgaatttt ctcaccttga agatgagata
    39241 tataaaacag ttggggaact tcgttgttca aaagaatttg ctttaaaaga aagacaaact
    39301 ctttcagata atcttgcaga tattgctcat caacttaaga ctccaattac ttctatgtca
    39361 cttatggcac aattactttc agaaaattgt ccagatgaag aaatagatta tattaacaga
    39421 cttacaaatc aaatctcaag acttgagaga ctagtttcat ctttacttac attatcaaaa
    39481 ttggatgcaa gtactttaat atttgaaagc aaacttatag atgtacattc tcttcttact
    39541 tatgcaattg agcctataga aggttcttta agagaaaaac atcagacatt tactatcgag
    39601 gcttctcctt cggtagaatt tgaaatcgat attaattgga ctttagaagc tcttttaaat
    39661 attcttaaaa attgtagtga gcatatagaa gatggtggat atatagttgc ttattatagt
    39721 caaaatcctc tatatgttga gattatcata gaagataatg gtaaggggtt tgctcaggaa
    39781 gaacttccat atatttttaa tagattttat cgtggtaaaa atgctagtaa ggacagtatt
    39841 ggtatagggc ttgctctatc aaagtctatt atagaacgtc aaaatggtac tatacatgca
    39901 gaaaattgcc ataatggtgg tgcaagattc ataattaaat tttacacata aaatgctgga
    39961 ttataggtaa aatacctata atccagctat atctatattc tatgttatct attgttttag
    40021 taatatactt ctatttacat ttaaggtttt attaaacaaa caacttaact atccctatac
    40081 ttgtaagtag tcttaaatcg aaacctttaa ataagttcaa atagattttg tttatattgt
    40141 ttcatttttt atagattcta ctatattttc attcttcaac tgcttgtatc ctgtcatata
    40201 tgatgctatt acaataaaaa gtatcaatat agtaaaacct attattgtag atataggtgc
    40261 aaatggtaaa tactctataa aatatatttc atttatacgt agaaaagcat acactattcc
    40321 tatttgcaca ggaatactaa gtagtaatgg tgtaattcct aagaataaac cttccaaaat
    40381 aagcatcttt tttatgcctt ctggagataa tccaacagaa cgcaacatag caaactcttg
    40441 tcgtctactt ctaatatttc ctgacactgt agcaagtaca tttgataatc caatcatagc
    40501 caataaacct gtaataaagc ctactattaa attcatggtc tttattccac tagcatcttg
    40561 tttttcactt tctaaaacat cctcaatact ataatctcct gaaccatagt ctttattata
    40621 aatggactct aatttttctc ttactctagg aatgtcctca cgattattta ctttaaatac
    40681 tcctatcagc ctatttgaac gtaacctact tacttcatca taatttttag atatttcctg
    40741 caccatagac attggaacta tttgcattaa tgtatacttt gaactagtat ctactatttt
    40801 aggaagtgtg cttgtaatag ctcccacttt catgttgtaa gtataatccc ctttatcttc
    40861 gtcatatact ttttcattta atttaatgtt atctcctatt gaaagattta aataatctat
    40921 atatacttta tttctacgtg tactacgatt aatatcttcc tccttattat atacaattga
    40981 ggttggattt tttgtatcat aaaataactt tgggtctaca gaaatttgcc tacaatattc
    41041 tgtaaaactc ttatcatcaa gcccaattat atttgaaatt atacgaaact ttccatcacg
    41101 ttctatagga gagtactttt tagatgaagc tatattttta aatcctccat ttttcgcaag
    41161 ttcttttgaa gcatcttttt cagtcaacca agtggaagca gacatttttt gataatatag
    41221 tgaacttttt acaccttctg tattatctaa tttttcaatg aaagcagact ctacaggttc
    41281 actattttcc aaataaactg ctatatctct ttggtcctta taattatcac ttccataaac
    41341 agcttttgct ccttcttgat tggcaattat atgcaaaaaa catgtaagta ataaaaaaga
    41401 taatgttaaa gatattgttg cagtacgata agatttttta cgagcacgta gtgcgtttga
    41461 tgcaagttct ccttctattc caaatatctt tcctaatgaa tatttatgcg actttttgat
    41521 tttaacacta tctccttgtc gtattgcttc tataggagat atctttgata cttttcgtgc
    41581 tggtataagt gcagaaatcc agactgttac tattgtaagt aaaactgctg gcagaaaagc
    41641 aggaatacca taagtaaata ccacttctgg aacatcagta tgataattaa ctgaattaac
    41701 ataaactata agcctattac acaataacca tcctaaaaat aaacctattg gtaatggtat
    41761 aattgtcagt aaaaagcctt caaacactac agacctttta atttgttttg gtgatgcacc
    41821 aacactagat aatatcccta actgagtaag tctagcattt gcagacagtg aaaacgcgtt
    41881 gtaaatcacc attacaaaca cggctactgt aaaaattgct attgtaagat acataatagg
    41941 agttgaaaat tttgatatac tactcataga tgctttctgt tctggtgaaa agactaacat
    42001 ctttaaaaga taattactat tgtatttaag attgtatttt ccatattcat tagtcttcca
    42061 tcccaatgat ttagcaagtt ttggaagttc cttatacgtg tctcttatat ttttaaatcg
    42121 caagtacaca gttatactat cattaggttt tatacttgtt ttatcaagat atccaagagc
    42181 tgtatatgca ggtattactg atgaagtaga aacatctacc tttcctacta ttgtcaatgt
    42241 agcctctgaa atttttttaa aactttcccc tttcgatttt ggggctatgg gttcaagagg
    42301 ctttccattt aggattctat ctcctattgg gagagtaatt ttatccccaa tttttacact
    42361 tggattattc tcaaaatatt gttttgataa tgcaatttca ttagcattat ttggtcgacg
    42421 accctctatt atagtatcct tttctggcat agaattccaa tactctgatg tagcatttct
    42481 ataaattata taatctcttt tctcatcatt aattttgcct acataccatt gtccttttac
    42541 cattacatca tcaactgaag aaaaattttc aattaatggt aagtcacttc cataagtata
    42601 gtcaaacaat tcaccatgcc agttaccttc tttctcaatt gaaagtttta taaaatctgt
    42661 ccacatggta tacaacagtc cacacaaaga agacatcatg gttgtagtaa gtaatatagc
    42721 taacattata gctatactac tacgtttatt gcgtcgtaca aagtctaagg tgtattcttg
    42781 aagaatattc atttcttcac caccttttca gagacaatca ctccatcttc catagttaca
    42841 atacgatttg cctctagtgc tattttctca tcatgagtaa taagaagtat tgtctgatta
    42901 aatcgtttat ttgataagtt taacaaatct acaatttctt ctgaattttt tctatcgaga
    42961 ttaccagttg gctcatctgc taataaaata gctggtctat aaattaaact tctagctata
    43021 gatacccttt gttgttgtcc acctgaaagt tgacttggaa gatggtttaa tctatcagat
    43081 aatcccaata tagatacaat ctcagagaat ctatcttcat ccacctttct tttatcaagt
    43141 aacatgggta ataatatatt ttttctaaca tcaagagtag gtataagatt ataaaattga
    43201 taaataagac ctacttttct acgtctaaaa actgcaagag cttcttcctt taaacttgct
    43261 atttctgtat cttcaacata aatctttcca gatgtaggtc tatctactcc cccaagcaga
    43321 tgtaacaatg tagatttgcc agaaccagat gctcctacaa tggatacaaa atcacctttt
    43381 tgaactgata aatttacatt attaagggct gtcactctgg tttgatttga accatatatt
    43441 tttgtgagat tttcacattt taatatttcc atatacaatc atctccttta tggttaaatt
    43501 ttagcaacct aaaatgacat tatagtgaca tgaatacaaa tataaattac tattaaaaat
    43561 attgtttagt ttttgcacat tatttaaaat tataatataa aacaaagact atgcaatata
    43621 ttttatttat acttttaata tattacatag tctttaaaag gtattaactt taaatctata
    43681 ggtattcaat ttaataatca atagcaagta ttttatgtac taaaggagtt ttgctctata
    43741 tagactcaat ttagtaaaat tatttaataa atattacaga ctataggtaa ataatattta
    43801 caaataaaat taagtttatt cccttacact ataatatttc ttaattatat taattgcaat
    43861 ttcctttacc tttggccctg taatttcttt attggaatca tctgatttaa tagcaaaata
    43921 ataggtgtca ccttcacgct ctagcatacc aacaaaccat gcatccacac gtttattttt
    43981 ttcatcaaat cctgttccag tttttccata tacatttatg tttttatcat ttacatctat
    44041 tttcataata tctcttaaaa tattaatatg ctctttttta aagtttgtat ctccctcaaa
    44101 tatttttgcc attgtttgca cttgttcttt tggagatatt tgtaatgaag attctaacca
    44161 aaatccattt aaatgtccct ttccattttt taaatctcct tcccattcgc taatatcgca
    44221 attcccatac tttaaatcat ctaaaatgtt ttggacatat ttagcatcaa ctttatttat
    44281 caattttttg tagtaccaaa cacaagactc cttaaatgcc tcttctaaac taagattttt
    44341 attccaattt ttatttggat actctgtacc atcatatccc ataactgatt cttttgaatt
    44401 tattacccct ttttctaaac caattaaagt tgaaactatt ttaaaagtag aacatggtga
    44461 ccttcttgtt tcaattaatt ctttgttata tatattatat tctttatttt tagtattata
    44521 aaaaatagct cctccactaa tatcttcaaa acaatcacta tagtcaacca tattaatttt
    44581 ttcttttttg tttttatcat tgttttcaat tttggattta tttaattcag acttatttaa
    44641 ttcagatttt atataattct tatcagtttt ttgatttata tcgttatgtt ttttccctaa
    44701 ataatacatt accataacta caccaaccaa taagatagct atccaaataa aattcttttt
    44761 tcttttcata atttatatca tctcccatat ttaaatttat aacctactat taaaatagta
    44821 tacattattt gtaatatact ccaatctagg ttctacttat aagaaacaag actaaatgaa
    44881 tagctgtatc tcttatattt tcttcaccta gtacaattat gttgattaaa cctattgcga
    44941 agataattag gtaactatta ataacatcct gtcctccttt taatttgtga tataataatt
    45001 gattccacat ttaaaactta ctattgtaat atttaaatat tacaatagta agttttaaat
    45061 gtcaagttac tttgggaaag ttattttaat tgtataattg ttattacatt tataaaatat
    45121 ggcatgttta aaattatttt gctattggga ggattaagat aagcagtatt ataaaagcta
    45181 taaattataa aatttaatat ataatttata gcttttactt ttacaaatat tgtttttatt
    45241 gatttattaa tgaattttat tgacaggtta tatttatata agtaaacact tacataataa
    45301 gtatataatc tacatatcta taagttgagt caattcacca gtatatgtca acttaagttt
    45361 atgcatagct cgtgtacaag caatatataa caaactgcgg tcataatcac tataatatgt
    45421 tttattattt actgaaggta caataacttc atcaaactct aaaccttttg acattttaat
    45481 agaagttatg gatactcctt ttgtaaagct agaactttca gaagatatta agtgaacact
    45541 atatttttct cttaacgcat catatacagc tttagcgtca ttatctgtct ttaatataat
    45601 accaagagtc gcattatcac tctttttaaa ttcttcaatt tctattttta tcttatttat
    45661 ttcatcttgc tcgttattac attttaataa agctggttct tcaccatgtc gttcaatagg
    45721 ctctaatgaa gatatgtctt gaatcttttt ggcgaaatta ataatctcaa aagtagaacg
    45781 gtaactctta ttcaacataa ctagttcccc atcattatat agctgtttca tatcatctag
    45841 tgtatgagtg tgattaggat taaccaattg tccaaaatct ccaagaatag tctttttaca
    45901 cttaaaaagt aagtttatta cagcatattg aataggtgtg taatcctgca tttcatcaat
    45961 aacaacatgt cttataatct tatcttcttg tataccttca tatgcagcat gaatatatat
    46021 aaatgggtat acatctgacc attcaagagt tttttttgtt gccatcacaa acatgtttga
    46081 tatattcatt tgtttaaaga aatccttata tagtgtaaga gtatttttta ttgtcaacat
    46141 tccattcaaa cttttaagta tactttttac ctttggtaaa tcttcttcca taatattatc
    46201 tgattcaaat ttataatgaa tgtcttcagc taccttctct aatctcttct taactggata
    46261 tctgttatat gcctcaaatc tactctgtat ccagtcactt ttagctgtaa aacttccaaa
    46321 agtgtagtct tttggaataa aaatcttatt tggcatttgt tttatataat catcaataag
    46381 ttttacaaaa tcaagtgtag atttaaaacg cactctttca gaccatttag catcatttat
    46441 ttctaatggg tctttctcac tttcaaaatt aataactcta tctaattgta cctctgctat
    46501 attttcaaaa cttaattcac ataatggctc ttctccaagc tcaggaagga cattggaaat
    46561 atagtctcca aagactttat taggtgatag gataattaca ttatttgctg atattttatc
    46621 tttaaatcga taaagaagaa aagcaattct gtgtaatgct atagatgttt tcccagaacc
    46681 agctacccct tgaataatca gtgtatcagc tttatcattt ctaataattt gattttgttc
    46741 cttttgtatt gttgaaatga ttgacttcat tttttcatct gaagtgtgac taagttcttt
    46801 ttgaagaata tcatcttgta tattaatgga actttctagt gcatattcta attttccatt
    46861 tttaatttta aattgtcgtt ttcttgttat ttctccatcc acccatccta ttggagcatc
    46921 atatccagct tttccgattt cataatcata aaacatactg gcaattggag aacgccagtc
    46981 aagtattata agctcatctt cataatcaaa tgcaaatcta ccaatataat acttagattc
    47041 atcatccata tctttcagcc taaaatctat tctagcaaag tatggagaat ctttgatttt
    47101 attaatctta tctcgaactt ttaccataaa agccccatag ttatctattt gttttagtcc
    47161 ttgttcattt tgaaacattt catgtgggtc tatttcacca cgatttttta ccatatacat
    47221 tttagcgtcc atataatcct tatcaagctt gtcaacaaga ttttcagctt tcttaaaagc
    47281 attgtctagc ttgttattta tctctattag atgtgcaatc tcatctggaa aaaaagttaa
    47341 taactctgca tcatattcac acatattatg tttagaatta gatgcaataa tatcgcaatt
    47401 tactacttgt ttattttcag acatttaaat cctcctttgt taattaagta cttacactga
    47461 atcattatac ttaattgtgt tttggagttt ttaatcattc ttgctattta acttaaagga
    47521 agaataaatt tttgagtagg atatccaaat tccacaagca actctgcttc tgcaaagccc
    47581 aacttcttta tcatatctct atgtcctgta tcagctttgt caccctctcg aaaggtagta
    47641 attgaaatat ctgtatctat caagaaatct tcaataactt tcttcaaaaa cacttgtgca
    47701 atgtctgaat tacgatactg tggatgtatt ccaaaaaaat caatacttct agtttctcta
    47761 ttaaacacca tatttgcaat agcgacatta ttaagtttta atattaaagc tctttcttct
    47821 aaaatatact gttctaattg atatatatat tcttcctctt gtaaatttgg aaatccatct
    47881 atgactaatc tcactaaatt catccataat ggtatgtcag acatacttgc aagtttaatt
    47941 tctttttcca actctagtac attctttgaa aataggttat cttttttcaa aacaaatctt
    48001 agctgcaaag gataaaattc ttgttctttc ctatatttat ttggagattt tttatacata
    48061 gctttaaata tagaagtgaa tgcctgttga ctttcatatc cagctatcaa tgcaatttca
    48121 ataattggtt tctttgaaaa tgccaataat tttgctgctt ctgtcaactt tctccgcttt
    48181 atgtaatcat gcattgttag gccaacagaa gttgtgaaag ttctatgcag gtgatatttt
    48241 gagtaatgaa cagcattagc aactatatct aaatccagct tttctgataa atgctcctct
    48301 atatagtcaa tagcagttat gacattaatt actttgtaag acattgcagc ttccctcctt
    48361 ttatccatgc aacattatat caattattac ttagttatat ttaatgaatc ttgctatttt
    48421 ataaacaaat ttgttgttta agttttcaat tcataaattt aatatattac tttttacttt
    48481 ctgattaaag actctaatcc tttaattttc aataattttt catttagtaa atctaaaaag
    48541 ttatttatta ttttcttctt attagattcc ttttatattc cttaattaaa tgataaatat
    48601 ttatattata cgactaaaaa cagcttttta caattattta atatgattac aaacttaccc
    48661 tatcttaaag tttaatgggg tcctgttatg aatcttttta ttttaattta agctcttcat
    48721 cagtttattt tatatattga tgtatttgat ttcatacaaa aaagagtgct tcatgaacta
    48781 aaaagttcat ttttaaacac tctcttttat gtaaataaat ttctattcta ttttgaaata
    48841 ttataatttg acttataatc tgttaatacc aaaaataata aattgtacgt ctaagaatag
    48901 attctaatta gttgctcagt agtaaaatct gtttttaact aatcctgctt tgtatgttga
    48961 acatattcta taattgtacc atctggatgt ctcaatgtca tattatatcc tgtaggaact
    49021 tttttcttat ctcttactac aactgctcca ttatccaata gataacttct ccattcatca
    49081 acagaatcaa ccataaaagt agattttgtt tctataaatg gtttaagagc atcatcagaa
    49141 ccagataata gtaaaacatt tcctatttgc gctaattcca acccaacttc tttataggaa
    49201 aaacgcaaag aacatttttc ttttaaaaga ttttcataaa aaggtatggc tttttctata
    49261 tcttgaatat aaaaacgtgt taatatatca tatattttca tattttcccc ctatatatct
    49321 atataatatt acctctaaat tataccactc tacaaattat ataacaataa attaagcata
    49381 gccttttgag catcttaagt agaccttaac aatatattgg ggttacatta gaatacataa
    49441 attaaatcac cttgatatta tttaggataa aatttatgta gtagcagtaa atgttcttct
    49501 aattatcaac taacaaacga taatctttaa ctttctatat aatgggtaac atcattttcg
    49561 taagatattc actagctgga cgattgatat catttaaata ctggtaatat atatcgccat
    49621 gaagtttata tccattgcta tttgcccatg aaaataagtc ttctaaagta gggtcttgta
    49681 attcataagg tcctaaatca attgcagtta ttattttctg tgcaggaaca atcctttgta
    49741 gaatctcatt tttcccatct atataagtgg ctacaggaaa ccctacttca acatccaatt
    49801 ttgctaaatc catgttatga aaacatacaa tcggtgctcc tgaagataaa attcctctct
    49861 cctccagata tttagaaatt ttttcaaaac tttgttttga aaactctgaa aactctacca
    49921 taaagtcaat tgtttttcgt attgccaaaa aacagtactc agattgttca gctattgtta
    49981 tattggatat tctagtcatt ttattcctcc attactttat tttcatttct aatcttttta
    50041 taccaaatta tacgaaaatt tactgtgtaa ctaattattt catatgaata taaaacataa
    50101 cctccttcca tttcttatat cgaaagtata gcaaaaataa tctcatcatt cttgtcacac
    50161 agtgctctta taatcagaac atacttaaaa gacttgccta atttttaggc aagtctaaaa
    50221 gaaatctttt tctataaaaa atttatacaa acaattaaaa gatcaaaata tagactaata
    50281 taaaactata aatttactaa tctgaacctc ccatggctaa agtcacaaga ttactgattt
    50341 atagaatttc gcacactaaa atatgtctta ctaattcccc acaggctacc cccctagttc
    50401 ctacgttctt acataagtta tctattatca aacatcaaaa tttaaacaag tttcaggttc
    50461 atcttctatt cttgctattt taaacttaca tgcaattaat actaaagata ctattggatt
    50521 tataatattt aataaagcgt atggaccata tgttagtgca gatacaccta atgttgctgt
    50581 tatatacgcc ccgcatgtat tccatggtac taatggagag gttaaagttc cactatcttc
    50641 taaagctctc gacaacatct taggatgtat acctctcttt ttatattcct tattatacat
    50701 tcttcctggt ataactatag atagatattg ttcacctgct attatattgg taattgtaca
    50761 agttaccata gtacataata ctgttccaaa tacacccttt gctaatctta gtaaagaaga
    50821 tgctactact tcaagcatac ctgttttttc taaaatacct ccaagagata aagcgcatat
    50881 tgttaaggat acagtggaca tcatattcat aatcccacct ttagataata aagcatctac
    50941 ctcctgtatt tgtgttgacg aaacatatcc attttgtgct gcatctaata tcgtattcat
    51001 agattctcct tgaaaaacta ctgcaaacaa tactcccaat acagcaccta ctataagccc
    51061 tggtatagca ggaactttaa atacaaccaa tccaattact attgctggag ctaataataa
    51121 tactggtgat aaagtattaa atgtagaatc taatgtagac ctaattaatt ctatttgttt
    51181 tatatctagt gcttgacctg aatacttcat tccaattaca ccataaatta ctaaacaaat
    51241 taataatgat ggtatagtcg aatatagcat atattttata tgtgtaaaca aatctgttcc
    51301 tgccattgct ggagctaagt tagtcgtttc agataaaggt gatagtttat ctccaaagta
    51361 agctccagat attatagaac ctacgattaa tccaattggc atacctaaac tttgaccaat
    51421 gcctaaaaga gctactccta ctgtacccat tgtgctccaa gatgaacctg tcgcaagaga
    51481 tactattgca cagactaatg ttgatgctac taaaaaaata tttggtgata aaatttttag
    51541 tccccagtaa atcatacatg gaactactcc acttactatc caagttccta taagtacgcc
    51601 tattataatt atgattaaga ttgcttgcat tgccatcttt atactattaa acatacttaa
    51661 ttctaactct ttccatttaa atccaagtct atatacagcc acaagtcctg ctactgctgc
    51721 tgctcctatt agtggtacat gaggtgatga accatacact aatactccta gacttaaaaa
    51781 taatatcaaa caagtaattg gtatcattgc atcaaacaga cttgcttttc tacattctcg
    51841 ctctttcata aaatagtttc ctcctaatta tttaaacact acactataat tttttttgaa
    51901 acatatttgc tcgtactaga tgacatgata cccccataag ttaataaaaa ttctaaattg
    51961 tcacctaatt tataatcata ttttgtgtta cttacatcta gtatcatgtg gtctgaactt
    52021 gcccctaata tttttatatc agtgtctatt ggaattaaag agtcaatatt tatatcttgt
    52081 ttacctatag ctatgattgc cctttttaag attcccttat cttcataaac aggtttattt
    52141 ctaaaggcat caactcctat ttctccaata ggaactgatg gtttttcttt acattcaact
    52201 acttggcata ttaatttaaa tgcatcttga tatgttccat ttatattttc accatatgcc
    52261 gtttctctac caagtagaat ggactcgcct attctcaaat tagtaatacc ttctggcata
    52321 ttattattta tcaacagatg aatagaactt gaattacctc cagatactat ttctagattt
    52381 attccaaatt tttcttccat tctttttgct atacttacca gtctgcctat attttcccta
    52441 gatggtataa tagctccata acaggttaag tttgtagcta taccaattat ttcaatattt
    52501 tttaatctta ctatctctct tacattacta aaaaagtctt cttcataaaa gtatccttct
    52561 cgtaaatcgc ctaagtcaaa cataagaact atcttatgaa taatattttt actttcacat
    52621 aattcattta atttctttat tgttcctaat tctgagttaa aactaatatc gcaataattg
    52681 ataacttctt ctaattcact taacattggg attctaatca atatcttagg tagatttata
    52741 tcttgtaaat tttttaagtt ttgtattctt gaatctgcta tatggtctat tccttcacta
    52801 catatttctt ctactatttc tttttgtgca caaaatgatt tagtaacaaa agatatctta
    52861 atatttcttt catgacacat ctgcgaaatt aattttgcat tatgctttaa cttttctata
    52921 tctatttcta acctaggata cataatcttt cctcctcaaa attcaaactt tttaacagga
    52981 gcttaagaga tgcttcttca tattttttag ataaaacacc catagatgcc ataatatagt
    53041 cattatctat taatatcttt gttttttcct ttggaaatag taattcatta tttttattgt
    53101 atttgagcat attatctaat atttcaattc tactagggag cctagtaagt gctccccctg
    53161 taccaactat atatcttact tctgttaaat ctttcccttc tgcaattttg acttttccag
    53221 ttgttccata gatatttctt atttttcctg aatgtcttag catagcttta acaacagctt
    53281 cttttgtcaa tctttcaaca aataatattt cttcttttga ttttggtatt ggaggataat
    53341 tctctattac tgcatcaata tctatagata gttcactttg taagttttct ttacctataa
    53401 cttctactat attcttcata tttacatata cacctaaatc cccctcaaca cttctctttg
    53461 cagtaggttc aggattaacc aaaattttat taatatagtc acttccatct gtaacagaat
    53521 gtacatcagt agttgctcca cctacatcca gagttaataa atctccaata tttttatata
    53581 aaagtttaga agcttccatt acagctcctg gggttggagt aatattttca ttaaccattt
    53641 ctttaatgta tttcattcct ggtgctgtag ttatgtgttc ttcaaataca ctttgaatga
    53701 ttcttcttgt aggttctata ttcaataaat ctattttagg gtatacattt tcagttatat
    53761 aaagcttata attagtatct tcaaatatta accttatttc ctcttgattt tcaacattac
    53821 cagcatatat aactggtatg cctagattca tagaagctat catttctgca ttataaatag
    53881 ctgtatctct ttctccataa tcgactccac cagctattaa aattatgttt gggtttattt
    53941 cttttatttt atttaaatca gttcttttaa ttctacctga tgttatttga cgaataacag
    54001 ctccagcccc taaagctgct tctttagctg cttttactgt catatcatag actaatccat
    54061 gaacagtcat ttttaatcca ccagctgcac tagaagttgc aaacatatca ttatacttta
    54121 tatcatctac agataattta ttagctaaat ctttaatagc acctgataag ccatttctta
    54181 catcgccacc ttcaaacact gttgttggag cttgaccttg acccaaaaat ataggattgt
    54241 tagtattaat atcgtggaaa gcgtttacca ctgtagtagt acttccaatt tcagctacca
    54301 acacatctat ttttaaagaa accttgctat tttccattat ttattactca tttctcttct
    54361 tttttcaact aagaaagtgg ctacatgtat gcctttgctg tttcttccaa atccagcatc
    54421 tatgccttgt tcaacagcta tttcaggtgt tacttgtgtt cctccacacg caatcattac
    54481 tttatctctt ataccttttt ctacacaata atcgtgtaat tttttcatgt ttttatagtg
    54541 aatatcatca tgacttatta ttgtagatgc aagtattgca tctgcattca gttcaatcgc
    54601 tgcatctacc aatttttcta caggtacaga agtccctaga tagtggcatt ctatgccata
    54661 tttttcaata cctccatgtt ttatatctat tatttctctt aaaccaactg aatgttcatc
    54721 ttctccaacc gtagctgaaa ctattttcat aggtttttct tctatatctg ctcttatttc
    54781 ttcatcagtt agtaccttag gttcttctgg tattactaaa ttgtttaaat ctatatcaaa
    54841 cggaactctt cctttcactt ctattctagt cccttcagat tcatgcataa cttctctact
    54901 tatgacctca atttcttgta agttcatttt tttgacaaat tccaaagctg caaactctgc
    54961 tgttctttta tcagtaggaa gcatcattgt tatcattaca attccatctg cacaccattc
    55021 catttcaggc ttaattttag ttccatttct gtactcatat gattctttta gtctattttc
    55081 tacattatca aaatcgtcaa gctcatcaat atatattatt ttgtctggat tttcaaatgt
    55141 acatccatct attaacattg atggattatc tatagcattt tcatcatatt gagctacatt
    55201 attgtatcca aagtgagcag ttacaggtgc taaataatct tcttctcttt cataaacagt
    55261 accttcacca actccacctt ttatttttct agatattcca tcaccatttc tttctggata
    55321 atttccagaa tcaacaaaaa atccttgttc cacagattca aaatatccac caacttcaga
    55381 tatttcttcc atatataata cagctctttc tttaagttct cttgctttgt ctcttaattc
    55441 accgacatct ttaagttcta tcatatccat aagcccatcc ataccaacta aagcttgctt
    55501 tgctgtatca catgcttcta tattgtatat atgccaaggt acatttctac cttcatcagg
    55561 tgttatagtt gattgtatgt cagctctagt taatactgat gttaataagt ttaatacatg
    55621 agtaactgtt gcttctctag ttgatgattc catatattta gtattcattt gagctctcat
    55681 cttataatca ctaaataact ctctaagtgc aaccgcgtaa ggtaagtcta tttttaaaca
    55741 tggtgctgga ggtgctgttg gtggaactgt tgataagcat atattacttt tatctatacc
    55801 tattttttct gagaatatag agtttaaagc gtgttgaacc ataagttcag gcattacctt
    55861 ccatgcttct ctagcagtag cattagcatt atgtgctcca tcaatttgag ctatattggc
    55921 aaaagccatt attttctttg cctcacaagc atctacaaaa gaccttacca tgtttatatt
    55981 cctatacaga acattatatt gtgggtcttg atgtgctcca ttgactcctt cctcagcaaa
    56041 cattactgct acttcaggac cagcaacacc acttacatat gaatggtaat taataggtct
    56101 accaacttct tcttctataa aatcaagagc cttcctttga gctcttactt gttttcttgt
    56161 tattggaact ccacctatac cttgtggagt tccttctata agcccatcaa aatgtgattg
    56221 tccagcagtt ctgataacca ttagatggtc agctccatga tgagctgcca ttctcattct
    56281 tcttatatca tcctcaaatc taccagaagc tatttcagta gtaataactg gacttggttg
    56341 agggtctata ttattgaaat acttagatga tggtagccct acactcttct ttaaaggttt
    56401 tgtacagtct ttatatttaa aaggtcccat ttcaagattt tccaagtgtt ctctccaaac
    56461 ccaacctctt cgttttggtt tatatttatc caaatctttt aatatatagt ctatatccaa
    56521 ttttttattt tcctttaaca tgattctacc ccttctctaa ataaacatgt aacttcatcc
    56581 caatattcac ccttaactaa taacaaacct gcttctctaa ccgttatatt tttagattta
    56641 gccaatttat aaactacatg ccctgctcct ttacctataa gacctctttc cataacccct
    56701 tctaaaatag gttttacttc aagagaagaa aatcccattc tcaacaagac agacctttct
    56761 attgatggtg ttgtattctt tttaccaagt tctatcattg gttctactat ctgggtagct
    56821 aaactccaaa acctttcttt taactcatca tcactcagtt cttgaagatg ttttcttcta
    56881 acttcaaaat catcctctct ttttttcatg aacattcctc cattcgtatt gatttaatcg
    56941 aattttctga atttttattt tatattaaat taaaaaacaa taattactat aaattattta
    57001 atacatcaac aacaaaatct cttgaacttt ttacttcttc cattaaaaat tctatatctc
    57061 gattacttag cttatcaata ttatcaatgt gattattaga tatacaattt tttataaatg
    57121 actttcttat tttattcata tcaatatcaa cacatttcaa taattctggt ctttctggta
    57181 atattaagtt tactcctgca atttcttctc ttggatttcc aaattttata tctattccat
    57241 tttctcttgc aaaggtaagt tgtggacata tatgtttacc tgcacccgta tattctgttt
    57301 cttgtaccac tatagcttta tcctcatcta gctcttgagc taaagagaat gctgctgcta
    57361 aagatgtatt tcctgctgga cctctttcta taccttctag ctgtgccaat aattcagttg
    57421 tataaaaaac ttctccttgt tttactaata catatctatc catatatcta agtggtctag
    57481 ctgcagacct aggtacatct gacctatcag gccatgtaca gtatggtatc ccaaaacctg
    57541 tatgtcctgt tgtaaatgat tttttattaa attgattatc actagccatg tgtaatcctt
    57601 ttaaatctac acttgctcct actactttag tattaataga accagctttt atcaatcctc
    57661 ttgcagttcc agtaagatta ccaccacctg catttgtaca aacaactata tcagggtctt
    57721 ttttatactt ttctctaaat tggatagcta actcataacc taaagtttct acacctgcaa
    57781 ttccaaatgg tgaatataat gatgcgttaa aatagcctgt ttcttctaat aaaactaaga
    57841 acgtataaaa taactctggt ccaacagtta actgaacaac ttctgctcca tatgcctcac
    57901 attttcgcgc tttttctatg atttcaggtt gacctacacc attagaatca taacattctt
    57961 gaactattat acattttaat ccctgcattg ccgcttgtga tgctacagct gcaccatagt
    58021 taccactagt agctgctatt acacctttat atcccatttg tttggcatga tatactgcag
    58081 tagctgctct tcttgcttta aaactaccag atgcattcat tgcttcatct tttacaaata
    58141 ttctagctcc tttaccttct ttagcacatt ttctagctaa tttagtcaaa tttttaagct
    58201 ctattaaagg agtatttcca acagcatact gtgattgaat tgcttcaata tcttgtaatg
    58261 tatatcctgt ttcactcatc attttctcat aatcaaaccc tattccctct tgttcaaaag
    58321 aagaataatc caatccgatt gcatttttca ttatttcgtt atttcttccc ataacagctt
    58381 gataactcat atctttcatt gatgttgaat tattcattat atacacctcc aaataatatt
    58441 tctttagctt ggattcctat ttggagtaac tctggtatac atttaccata atcatgagta
    58501 taatatggat ttattttaag taaattacct tttacaagtc tgcctgtaat tgttttaact
    58561 tctactaagt cgcctataga agcatcactt tgtataaaac ctttaaccca catttctaag
    58621 gatactttct tagtatcctc tggaacttgt ggagctcttt cttctggagt caatactata
    58681 ttgtgtataa taacccaatc attaatttta gcatccattt tttcatcccc ttattaattg
    58741 actattgcct tactaattaa tttactgtta ttttaaatta aacattattt taccaattag
    58801 ctaactgtta tcttactaat tagctagttg ctatcttact aattagcctt tgattcttct
    58861 tccaattcaa cttctatctg atttcttata tctcccatta ttgctctagg tactggtata
    58921 tccaacatag ttttaagacc tggtctagca tttattatta atggaataga gtttactatc
    58981 attgcataag tacctactcc tccaggtatt tcaggattta tttgtaaatc aatgtttggt
    59041 atacctttta ttgatacata gtctcctgtt ttaatacctt ctgcttctgg tattatctgt
    59101 tgtggatgct ccatttcaat taaaacttct ccatttacat atccatatcc acattgtcta
    59161 caaccagcaa catttccagc caatgcctct ccgtacttag attttctatc tactgtagtc
    59221 attattggct cttttgtttg ttctatctta tctaatttcc aacctaatcc atcagctatc
    59281 atatttattg attctacaaa acctacatga cctgctatag tcttatcttc tacacctttt
    59341 ataaattctt cccttgttac tccaacacct tgttccacca taacagactt tccaaatgga
    59401 gataaatcat ttactctctt agcttttata ctagtaactt cttcacaagt acctgaaagt
    59461 gccaatacta gtaaatctaa tacaaatcct ggatttattc ctgttccaag tatacttact
    59521 ccattttcct ttgcaacttc atccattttt ttagctaaat ctgcatcatc agcttgtgga
    59581 tatgccattt gttctgctgt tgatataaca tttatttttc tatttaataa gaaaattatt
    59641 ttatcaaaag cctttttagt aaatgaatca gttgctaaca aaacaacatc tacacttttt
    59701 tctctaaaaa cttcttcata atttttattg ataataactt ctggtctttc tcctctttca
    59761 attcctaaaa cattatacat actttttcct gaagtacttc tactacaaac agatactatt
    59821 tctatacctt ctttctttag aatcatatta gccataccta ttcccatagc tccaaatccc
    59881 catattccta ctcttacttt tctcatatat acaccctcct aaaaatttat atattctcaa
    59941 taattagtta aagcataaat cgtgccaact ttaaaattaa agtaaatatt tattggaacg
    60001 ttgaaactat aattatttta ttatgtattt tcataaataa aaaataatat ttcttatgag
    60061 aaataaaaaa aagagcaaaa tattttgctc ttttataata attttgctcc tctattttgc
    60121 ttttttattt tactttgatt ttgttttttt atcttgctta tttataatat tttgatatta
    60181 tattttttta ttttatactg taaattttgc ctattcatac ctaaaattga tgcagcttta
    60241 gttatattgt aagatgcctt ttctaatgat tcatatatat acttttcttc tatctcactg
    60301 ataatcttac taagtgtttt gtcctccaaa tcgtttaaag aataattgtt actctcttta
    60361 ttctctttaa gattgtaata gtcgtttaga ttaatcatac ttgtttctat ttgtacctca
    60421 tcttccatca tactcatagt acaataaatt atgttttcta gctctcttat gttaccttgc
    60481 caatcgtaat tttttaaaat tttaatagct tcatctgaaa ttcctaccac ttttttattt
    60541 aactttttat tatactttga aataaatttt ttgcacaata gaggtatgtc ctcttttcta
    60601 tctctaagag gaggaatttt tatatgaatt atgttaagcc tataatataa atcttttcgc
    60661 attttatgct cgtttaaaat tacctttgga ctttcatttg tcgttgcaat aattcttaca
    60721 tctataggta tatccttagt tcctccaacc cttcttacat aaccttcttg taaaaccctt
    60781 aatagtttag cctgtaacat aataggcatg gaatttatct catccaataa caatgtccct
    60841 ttgttagctt gttcaaataa gcctggccta tctattgctc ctgtaaatcc tcccttgcta
    60901 gttccaaaaa gaataccttc gaatagtgat tccggcaaag ctgcacaatt ttgtgctata
    60961 aatggatagt ttttcctatt acttccatag tgaatggact ggctaaataa ctctttaccc
    61021 gttccagttt caccgtatat aaatactgaa gcatcagact tgcaagcttt cttagattta
    61081 gctattgctt ctttaatcaa attactttcc cctaaaatat catcaaattc ataacccttt
    61141 ttttgtctac tactaacttt attgactaaa ttttttttat aatttctatt tagtaaattt
    61201 tctatcgttg tcatattctt tgatatctca agtgccccta caaactcgcc tttaatatca
    61261 attggtattg tagtattaat tgctgttatc tcttttccat ttttatccag atatttttga
    61321 atattgtctt tgataacttc ccttttttcc aaaacttcta atagtgtact cctgtttatt
    61381 ttcattttgt tgactatatc aaaaaatgaa ttggttaaaa tatcgtgtct gttcattttt
    61441 tccatttttt gtacagaatt attgtagatt atagttttcc cgtctttatt aacaaaatgt
    61501 accccttcat caatattttc caatatttca ttcattattt taaaaaatat ctcttggttc
    61561 aactatatca ccccagtacc taaatatata aaaacccaaa aaattaataa aatgttgcta
    61621 ttgtatttat cttatcatat atttatgat
//
LOCUS       DAMKNB010000015        61286 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.015, whole genome shotgun sequence.
ACCESSION   DAMKNB010000015 DAMKNB010000000
VERSION     DAMKNB010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 61286)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 61286)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..61286
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.015"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            153..1658
                     /locus_tag="PC494_001095"
     CDS             153..1658
                     /locus_tag="PC494_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HDF3911615.1"
                     /translation="MKIQNTEWGYIEWKHTYDENNPKQAMNIYIAVTMPGKKHFNHVH
                     YGQEQMIYILEGEGLYIINGVWKPFYQGMIFYIESGSTHETINTGDREIKELIVSNNV
                     DDVGESEVIDINPNNYLKKTLINYSESTLNLYAAVESIRGQFIDPFKIPLIIYDDSWN
                     IVLKNPYFPLFCFEKCNPMKFPQNCDCMNQKSSNQFVCEYGITIYNIPILYKSNSIGV
                     IRGGYVLLSDLNLDTEHNNLYDIPEGAARSIKRLLKQISKNIINFCSFNDIRKDLQEK
                     EKTIARTYHYGEQLEMNLKVAQDMVTNLRINHHFLFNTLNSMASIALDDGSYDLYSAI
                     IDLSRMFRYTMRSDLRFVELESEILYIKNYLNLQKLRYGDALKVKYLIPEKLYNLSVP
                     FNFIQPIVENAFTHGFRDIDTEKRIEIIARLDSQYAIIEIHNNGTILDGNNIDKIKAG
                     IRSNNGHGLSLIYTKFTSAYGNNFDMDIKSSDNEGTYIMIKIPIENYKEYV"
     gene            1772..2470
                     /locus_tag="PC494_001096"
     CDS             1772..2470
                     /locus_tag="PC494_001096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HDF3911616.1"
                     /translation="MRRALIIDDEEAVLKIITHFIEMKDMPIKIVGKATSGDEAVDKI
                     IGLEPDIVFIDIQMPIYNGLEVIEKTSHLSKKINFVVITAFNYFEYAQKALRLNVKDI
                     LLKPLDMKEFTKSVEKIIGYQYTNNDLLNEILEYINLNYSNDLKLNDCARLFLTNPSN
                     ISRIFKSNLNTTFISYLNHIRIEKSIELLENTTKSINEIAEIVGYNSLNNFYKNFKIE
                     KGMTPKVYKLNTKN"
     gene            2755..3843
                     /locus_tag="PC494_001097"
     CDS             2755..3843
                     /locus_tag="PC494_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3911617.1"
                     /translation="MSDKVNMKNIICIAGAYLATAIGSGFATGQEILQFFASQGYMGL
                     IGALISMVLFSFLGAEVITRGRELKLKEPTRIYTFYCGKILGKFYEWFSPIFLFGILI
                     VMISGAGSTLTEYYGINPYLGRVLMAVATLITVSMGLEKLVSILGRIGPVIAVFTIAV
                     GLISLFKHFDGLSMVGEAMKNIEVTKASESPIVSGVIYNTLNIIVMIVFLTGMGASIE
                     SKKDAFWGGLLGGIVFMTAGIVMYLAMISDIGNLYMKEIPSLYLADNISPIVGVCFSV
                     ALILGIYTTAVPLLWSVTNRIVEDEHPKFKLVTTVIAILACIGGFLPFGKLVNILYPY
                     TGYMGLLILVCMVYKAITCRKKSTQSQE"
     gene            4082..5272
                     /locus_tag="PC494_001098"
     CDS             4082..5272
                     /locus_tag="PC494_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HDF3911618.1"
                     /translation="MHELILISEKYKEDILDFFTDIHMHPELSFKEFRTTKAIKDLLV
                     SLDIEILDLGMETGVVGLLKGKYDGPTVALRGDIDALPIYEEVDIKYKSRYDGIMHAC
                     GHDIHTSCLVGCAYVLSHIRDSLHGNVKFIFQPAEEVNKGAKMLVERGVMENPKVDAI
                     FGLHNHPDIPCGKIGVKLGGLMAAVDTIKIEVNGFGGHGGIPNRTIDPIVASSAIIMG
                     IQTIVSRNISPLESAVISIGTINGGTANNVISEKVDMTGTCRSFSNEVRKKISENLEN
                     IVCEIARGYQATAKLDYLFDLPAVINSKEMYAIACKSVCDLYSEDAIVDPIPSTGGED
                     FSIFMEKAPGFFYWLGVGNKEQDCIYQWHNPKFKADKNSILVGTNVLCQSVINYMDKL
                     KNKI"
     gene            5363..6865
                     /locus_tag="PC494_001099"
     CDS             5363..6865
                     /locus_tag="PC494_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbgT family transporter"
                     /protein_id="HDF3911619.1"
                     /translation="MRALNVVERAGNKLPDPVTIFLLLCIIVVILSAVISNLGVEEIH
                     PSTKEVVKVVNLLEKEQIQSYLGSIVTNFQSFAPLGLVLVTMLGAGVAEKSGFMEVLM
                     KKGISKVPQKLVTVAIVFAGMLSHTAADVGFIILPPLAALVFLGIGRHPLVGMFAAFA
                     GVAGGFAANVMLSTTDVLLAGFTIPAAQMMDPSYQGNPAMNLYFAFISAIVLTFAGAF
                     VTEKFIAPRFTKYNDSTNDKDIQELSELENKGIKYALLSLLVVVVVIVALCIGDNAFM
                     KDPETGSILSSNAPLMKGIVPIITIIFLTPGLVYGKVSKKIKSDKDLVSMMGSSMSDM
                     GGYIVLAFIASQFINLFNLSNLGTILSITGAKLLAESGIPSYGLIIGFILLSGFINLF
                     VGSASAKWAILAPIFVPMFMLLDFNPALTQIAYRIGDASTNPISPLFPYFPVILAFAR
                     RYDKDIGIGTVISNMIPYSVVFTLIEIIILLLFMGIGIPLGPGGGISYVL"
     gene            6937..8193
                     /locus_tag="PC494_001100"
     CDS             6937..8193
                     /locus_tag="PC494_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HDF3911620.1"
                     /translation="MLKTTKISDPELYKIVADELVRQEHNIEMIASESTAPTEVLELS
                     GCVFTNKTEEGYPGARFQAGSEEADKLETLAIKRAKEVFGAEHVNVQPYSGSTANYCV
                     YSSILKPNDTVLSMRLDQGGHLTHGSAVNFLHDIYKYEFYGVDPNTGRIDYDALEAKA
                     KECRPKLIIAGASSYPRLIDYERISKVAKEVGAYFMVDMAHVAGLVAAKVIPSPVPYA
                     DFVSSSTTKTFCGPRSGIVLCKAEHAKKLDKGVFPGTLGSIHLNTVAAKAFSLLYLST
                     DKFKKIMEQVVVNAQTLASELISHGFSIVSGGTDNHIVMVDLRSKNLTGKQFEKALEY
                     VGITVNKNVIPDDPQSPFVTSGVRIGLTSISQRGLKEKEVIQIAGIMNKVAENIDNKE
                     VLDECKAEAQELISKFPLYPEGYFED"
     gene            8365..11139
                     /locus_tag="PC494_001101"
     CDS             8365..11139
                     /locus_tag="PC494_001101"
                     /EC_number="7.2.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="calcium-translocating P-type ATPase, PMCA-type"
                     /protein_id="HDF3911621.1"
                     /translation="MRYYNKPTKEVLKYLKTNPEIGLDDNEVEERKLRYGLNEFTIKE
                     GRTFWDELGESLTEPMILILIGAAVISSFVGELHDALGILGAIFIGISIGIITEGKSK
                     KAAHALSKLTENIEVKVLRNGKIIKISKNDLVPGDIVYIETGDMIPADGRLIQSINLK
                     LREDMLTGESDDVAKNADAVLDMEVVYSKTEIIEQDAIPAKQVNMVFGGTLVAYGRGI
                     MVVTHTGDKTEMGKIAQNLSNEDQQTPLQIKLGKLGAKIAGISGVIATLLCMFMIIQM
                     QRKGMLILDTSSVLSFLQSLEPAKNAYMVCIALIVATVPEGLPTMINITLAITMQKMA
                     KINALVTKKEACETIGSVSVICSDKTGTLTQNKMMVEVAYVDGKYISGGEYQSNSYFE
                     QNCIVNSTADIEKEDNSFKYIGSATECALLLYHNDKNYNEMRKQTYLISQIPFSSEEK
                     KMSTLIRQEDSDILLSKGAPEVLLKKCSYVQQGKNIVPITPKVEKSILDEIKKLQIKS
                     MRTLGFAYKKMSNSKTEVAVTSEGELNLIGNSRSYMKEDNLVFSGFVGIVDPLREGVK
                     DSIDKAFNAGVDVKMLTGDNINTATAIGNELGLLNDGKKAVEATYIDVLTDKELREEI
                     KGISIVARSKPDTKMRIVSALQKSGEVVAVTGDGINDAPALSQADVGIAMGISGTEVS
                     KNAADIILTDDSFSTIVEGIKWGRGIYENFQRFIQFQLTVNIVAFIIAIISQLTGKDM
                     PFTTIQLLWVNIIMDGPPALALGLEPVRDYVLKRKPINRHSGIIARSMFVNIIINAIL
                     IITIVFTQSAFNILGATSEEQGTVIFSLFAFSALFNALNCREFGLNSTIPNFFKNKLA
                     LQIIVVTGIIQIIFTQVFQSFFNSVSLDFDMWIKIILFASTILLSNEFVKLILRTMKN
                     SRTMNFNSKN"
     gene            complement(11240..11389)
                     /locus_tag="PC494_001102"
     CDS             complement(11240..11389)
                     /locus_tag="PC494_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HDF3911622.1"
                     /translation="MFFISYIYTKSPIEFDTPLQKEAYKILQKLDIDFECVDTDEAIT
                     MEDCV"
     gene            11764..12942
                     /locus_tag="PC494_001103"
     CDS             11764..12942
                     /locus_tag="PC494_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HDF3911623.1"
                     /translation="MFSKILVKTFIRDSENVQNTDVRNKYGYVAGVVGILSNLLLFVI
                     KVFIGMLTSSIAIMADAFNNLSDMASSAITMIGFKLASKPADKEHPFGHGRIEYLSAL
                     IVAFMVMLVGLQFVKSSIERIVNPIPVKFEVIPLILLIASIMIKIWLSRFNKFMGNKI
                     DSSALKAVSLDALGDVFTSSCVVISFIVARFTNFPIDGYVGIVVSLVILYAGFSLVKD
                     TINPLLGEAPDEEMVNSIIELLLSYKYIIGTHDLIIHNYGVGRCIASIHAEIPSNIDI
                     MEIHEIIDTAEREISEKLDIYLVIHMDPICLEDKEVMSAKKELEEILKKNSLVKSMHD
                     FRIVGKGSKKNLIFDIVVNPSEFSKNMSEDDLKEDITKLVKEINPEYNCVIVVDKDFI
                     "
     regulatory      13069..13154
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01786"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class II; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01786"
     gene            13272..16190
                     /locus_tag="PC494_001104"
     CDS             13272..16190
                     /locus_tag="PC494_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021362860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SrtB-anchored collagen-binding adhesin"
                     /protein_id="HDF3911624.1"
                     /translation="MKKGNRKALLISLIMILSMVVSTIYPTVSYASELGENSQIQSGS
                     TNSSTGEEKESDNKKPEQTPEKDKATDNKKPEQTPEEEKPTDNKKPEQTPEEDKSTDN
                     KKPEQTPEGEKPIDNKKPEQIQEEDKSTDNKKSEQALEDEKPLDNKNTEKTPEEDNLL
                     EDENLLKVLEEELNEENEDYGFVVKINNNTIETESMKKISFNLTYTPTSKGIQAGDSI
                     TFKVPDVFNKVNLDYTSECFDKTESNGEYTLTFRELPNGQSVMQGKIGLEAYVKKVDE
                     DTNAKIHIETTGKIESGSGDIDVEIKPGDKTDVPDAKGTLKKLVEGKKSTTVFMPVKN
                     KDINYSIQVNEKQEELKDIILYDELPEGLTLINGSVSVVTSDGKEVSDFNIEQSKNSI
                     SVNFGNIDKSYTVKYKARISDKNAKHGNKYKNVARIESDGKKIQEDDATVSIFDRGDD
                     YLLTKGHSGATNITQVGQVINYQISINDDKSPISNVVITDNIPEGMRLTTSGEAGHDF
                     RVVEIPMNGSWTPWSKEKIANNISYKVEEKRNESGQVDKVITGFTINLSKEEVESKFF
                     IAYTLKVISIEDSYINRAVLDANNSEIDKNDEINFKKNSGLISAKKEVDKKVLNSSDN
                     QIVKYKINMSTYGVYDAGQVNLLDEVNSVLEISNIKYSDNLELKKEAGDGKNTIRLVN
                     KYEFKQIKEGEPVQSWVTFDANFTNVKVGETIRNVAQINGSSPPGVETTKQGYAFEAK
                     KVDALDKNVLSGAKFNLEDAFGNIVVKDLVSDEDGIIQSSVKNPGTYYLVEIMAPRGY
                     EKLKDKVKVEIGNEDIGKIVDIGNIENLKQENPPVNPPIPPDTDEPIVNPPVPPSTDK
                     PRKPSSSSDTENTIVINPPVPPSEDIINPPIPEVLNPPVPPSEEMIETPVKQIIPIPE
                     VVKPSVSEEKNNKVKDDTLVNPPVPPKTGDSTTIIGEILLVIGAIVGLIVLRRNKNTN
                     "
     regulatory      16375..16460
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            16560..17222
                     /gene="zmp1"
                     /locus_tag="PC494_001105"
     CDS             16560..17222
                     /gene="zmp1"
                     /locus_tag="PC494_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metalloprotease Zmp1"
                     /protein_id="HDF3911625.1"
                     /translation="MRPSKKLLIAIISIFLISSVPVSAHADSTTIQQNKDTLSQIVVF
                     PTGNYDKNEANAMVNRLANIDGKYLNALKQNNLKIKLLSGKLTDEKEYAYLKGVVPKG
                     WEGTGKTWDDVPGLGGSTVALRIGFSNKGKGHDSINLELHETAHAIDHIVLNDISKSA
                     QFKQIFAKEGRSLGNVNYLGVYPEEFFAESFAYYYLNQDTNSKLKSACPQTYSFLQNL
                     AK"
     gene            complement(17344..18306)
                     /locus_tag="PC494_001106"
     CDS             complement(17344..18306)
                     /locus_tag="PC494_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HDF3911626.1"
                     /translation="MKKGYVYIILTTLFFSSMEISLKTVTNDFNPLQITLSRFFVGGL
                     VLLPFAVKRLRALSLSITKSDLKYFAFLGFMCVVVSMSLYQLAVLNTKASVVAVLFSC
                     NPVFVMLLAYLILKEKIYRHNVISLILEVLGIIVIINPLHTKLTLSGIFLTLSSAIIF
                     SMYTVFGKRKTLKFGGIVVTCFSFIFGSLEMLILVLLTKINFIADILNKNKLHVFANI
                     PIFSGYTLHNMPIMIYVFVFVTGVGYALYFMAMEATSTSLTSLVFFFKPVISPILALL
                     ILKEIIPINMVIGILLIVIGSIISIIPTIITQMHNKHVEALYKE"
     gene            complement(18476..19666)
                     /locus_tag="PC494_001107"
     CDS             complement(18476..19666)
                     /locus_tag="PC494_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HDF3911627.1"
                     /translation="MISNKMQTLVANSSVIRAMFEEGKKLSDIYGEENVFDFSIGNPS
                     VEPPETIKAVINDILNEESPNLVHGYMNNSGYEDVRDAIAEHINKKDGLNLTRENLIM
                     TCGAAGGLNIILKTLLNPGDEVIAFAPYFGEYKNYTENYDGKLIEVPTNIETFEPDLD
                     ALKNAITPKTRALIINTPNNPTGVIYSEELLKNLGELLDSKQKEFNTSIYLISDEPYR
                     EIIYDGAKVPCVLKYYRNSFIGYSYSKSLSLPGERIGYIVANGQMDDFDDVMSSLNVA
                     NRILGFVNAPSLFQRVIARSLDAEVDVNIYKKNFDLLYNSLIDMGYSCVKPNGTFYLF
                     PKAPIEDDKKFCNDAKQFNLLLVPGSSFGCPGHFRVSYCVSYDKVKSSLPAFEKLAKL
                     YNLK"
     gene            19972..20418
                     /locus_tag="PC494_001108"
     CDS             19972..20418
                     /locus_tag="PC494_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HDF3911628.1"
                     /translation="MDFKNLQYESLSYIICNLQKNFKLYCEKCLKPYKLTNGLYFYLI
                     YINKNRNCSLNDVSTEFEVDKAHTTRTISRLEQDGYIEKIQNPNDSRAFQLRVTDKGE
                     EVLGDIKNIFSKWDNHIKKEFSDTEYKELVKNLHVVKDIKTAVEEE"
     gene            20420..21514
                     /locus_tag="PC494_001109"
     CDS             20420..21514
                     /locus_tag="PC494_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH:flavin oxidoreductase"
                     /protein_id="HDF3911629.1"
                     /translation="MYCNLLKPIKIGNLELKNRVSFAPTSMGLKLEEKIKKFSDIAKS
                     GVALITLGDVSIRPSFHKVAISLSDEDGVIKYKKIVDEIHNSGAKVSAQLFCSDYDVN
                     LIKDTMNMGITSHDEIKKIMNDGVKDYITNMPKEEIKNIINLFKVTALNAKKAGFDMI
                     QIHGDRLVGSFSSSIFNNRNDEYGGTCDNRSRFASEIISSIRDEVKDIPIDYKFAIRQ
                     ENPHYGNAGVLLSEVEYFVKKFESLGVNSFHVTLANHSKLEDTIPTNNHPYFKDEGCF
                     LYLADEVKKHTNLPVCGVGKLSSPDFIESIISNNRVDMVSMSRQLLADSNWLQKVKDG
                     RVDEIKKCCYCNKKCADALQTRSQFGCILD"
     gene            21602..22132
                     /locus_tag="PC494_001110"
     CDS             21602..22132
                     /locus_tag="PC494_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HDF3911630.1"
                     /translation="MKSLVLYSSLTGNTKKIAYTIYDEIQEEKDIKDVNELVDYGIDY
                     ENYDIVFLGYWVDKGICDKNSKQVLENIHNKKIALFGTMGASKKGSYGASIIEKIESI
                     IPKDNEILGSFICQGKIAEGLKAKYKEMLKLSPDNEHIRQQLNNHEESQSHPDEQEIY
                     EASMFAKNMMIKASIV"
     gene            complement(23067..24443)
                     /locus_tag="PC494_001111"
     CDS             complement(23067..24443)
                     /locus_tag="PC494_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3911631.1"
                     /translation="MKYKIGFLTTSYFMSDKFKQALKELNDTCEITFIELKGENPFNN
                     LPNIYYEQVDNFDGFVCSGIVPYSELIINIKDIKVPLNFLKLDERDFYKYLFKLLNSQ
                     KDIDFTKSFMDFLREDNNYYDIYSLIDSNKCPYTIKDFNIPQPVYDFKKLNDKLLEIH
                     LDLLRDNKINLSFTRNYIISCELNKLGYDCIYMVPSTESILNTFKSLVNEITLQNLDK
                     NKSATCIVTVNSSEYINEDLIFKNDEIQNQIYNTILNSLSRHGFYGVQVKKNDMKIEI
                     HTTKEMLNNMTNNYTDFFISEDLKEIKYSLNIGWGIGNTNIHAEQNARQANGKSASLN
                     GNCTFIVNDTNDTIGPLYSNKNSNNIEDSSIANKVASFIPLSNTNVSKIMCMINDRNS
                     NNVSAEILADYMNITLRSANRILSILYKAGIATIVNTKLDNQRGRPKKIYKVDFLSFL
                     NKMQKLNS"
     gene            24712..25884
                     /locus_tag="PC494_001112"
     CDS             24712..25884
                     /locus_tag="PC494_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HDF3911632.1"
                     /translation="MNTYLNEISKFVDENREEIVSLWKEIVNMESYTHCKESVNKLAK
                     RLKFEFEKEGLDCELVDVGDNGSTLIGTLGSNIDKKPIIFSGHMDTVFETGTFGENPF
                     KIIEGKAYGPGVLDMKGGIIISLYVIKALNKIGYKERPIKIVFSGDEEIGHKDSTGAD
                     VILREAKGGLCAFNMETGLVDNSLCVGRKGRIGCNIHVKGVETHAGNDFEGGRNAIEE
                     MANKILRIQKLTNLDVGTTVSVSVIKGGRVENSIPEDCSIKVDLRFEKVEEMENVKEQ
                     VREICKETYIEGTSTEVNFISEMMPFETTEDVMRFHTFVNEVSKENGFGELNAKRLGG
                     SSDASYLTIANVPTICSFGVRGEWNHTSREYAVVNSMFERVKLISTVILNLDKFEV"
     gene            25898..26545
                     /locus_tag="PC494_001113"
     CDS             25898..26545
                     /locus_tag="PC494_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3911633.1"
                     /translation="MDVTAGDNKVTWKGYLSLFVLIVLFSGVFKDSQGFLKALDFANL
                     TGSFGTIADGVDFMGKGGTGAKDGFLFALTLIPTVCFAVGLIDVVESMGGMKAASKIF
                     NPLLRPLLGIPGIAGIAFVSSFTSSDVASIMTKELFESGEITDDERTIFVAYQYAGSA
                     VILNTINTQAPLLPIALLALGPIILIEIFCKILGANLVRLIIGVRNKKNKAKEAV"
     gene            26547..27056
                     /locus_tag="PC494_001114"
     CDS             26547..27056
                     /locus_tag="PC494_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjiG family protein"
                     /protein_id="HDF3911634.1"
                     /translation="MSQQNTGNAIVNSKPKKTAVEIFMGGAKKGFYIGVEQILPAMIM
                     GYVIVQFLQLTGLVDILGNIFGPVMGIFGLPGESVVVLIAAFFAKAAGAATAANLFAQ
                     GLITAPQATILIMPCMLMGTLVGHYARIVLVANASTKYRMLLLAVPIFDAIVGMLIVR
                     VLLTVMGLM"
     gene            complement(27420..28532)
                     /locus_tag="PC494_001115"
     CDS             complement(27420..28532)
                     /locus_tag="PC494_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HDF3911635.1"
                     /translation="MKISEVATPNFLLDLDQLEKNIDKIQQICTNNNKQLWPMLKTHK
                     STYIARLQKNAGASGFLVGTLDEGEALIKAGFEDIMLAYPYMGEVNINRIVTMASKIN
                     LICATDNIECAKAYSEAFSKSKIECKLLIIVDCGLHRFGVEPEKVVELATEISKLENI
                     KIVGISSHPGQVYGCSSPEGVPDVCVQEDSSMEKAYKALTDNGFNIEIVASGSTPTVE
                     SEAASKTITAVRPGNYVYYDAIQIGLGCATEDMCALTVVCTVISKNSSGYYLIDCGSK
                     CLGLDKGAHGNSSIVGYGRVCGHPELTIDSLSEEVGKIKVNGETDIKIGDRIRIIPNH
                     SCSTANLTSNLLGFRGDTIEKVIEVDIRENSKQIIL"
     gene            28830..29096
                     /locus_tag="PC494_001116"
     CDS             28830..29096
                     /locus_tag="PC494_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase family protein"
                     /protein_id="HDF3911636.1"
                     /translation="MNLEPKKLIEQIGKEKDKKDIWIVGGGDIVKLFMKDNLIDDYYI
                     YILPIILGRGISLFKSGIDKTNLNFKKASNIGELVKLEYSKKQK"
     gene            29341..31068
                     /locus_tag="PC494_001117"
     CDS             29341..31068
                     /locus_tag="PC494_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003496244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF3911637.1"
                     /translation="MKLILSYLKNYKLLIVLNILAIFSFALVELGIPTIIAKIIDNGI
                     ANQNIAYIKQMGIVIVIISIIGVVGSILLGYCSAKVSTSVTRDIRNDIFEKSQEFSHT
                     EYNKFGISSMITRTTNDAFQIQQFVNILLRTALLTPVMFIISIIMTIRTSVELSIVLA
                     ISVPFIIIGVAIIAKVSQAISSKQQKGLDKLNLISRENLTGIRVIRAFGNDDYETERF
                     EKTNTYYANVSKKLFKLMSITQPAFFLLLNIAVLAVFWISSEKINIGELQVGQLVAFL
                     EYLFHAMFSIMLFSMVFIMYPRAEVSANRIKELLNEEPLIKNPENGIKDTENKGIIEF
                     DNVTFTYPDGEASVLKDISFTAKTGETVAFIGSTGSGKSTLINLIPRFYDVTEGSIKI
                     NGVDIREYDLKALRKKIGFIPQKSLLFTGSIANNIRFGKHKAGESELEYSAKVAQAYE
                     FISKKPRKFDELISEGGANVSGGQKQRLSIARAIIRRPEIYIFDDSFSALDFKTDAIL
                     RAKLKKETKDAIVLIVAQRISSIIDADKIIVLNEGQVVGMGTHKELLKNCEIYYEIAT
                     SQLKKEELE"
     gene            31068..32858
                     /locus_tag="PC494_001118"
     CDS             31068..32858
                     /locus_tag="PC494_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF3911638.1"
                     /translation="MKKSKGFKKTIGRLLPFVKKYKFSFIIAIICIISAATMNALAPK
                     TEGLIITQLTKDVISIAKGVPGASVNFDYVTKILVILACIYFANAIFTYTSSFLLTNA
                     IQNTMRDLRNEVENKIRRLPISYFDSNSFGDVLSRISNDVDTISNALQQSFMQIVNSI
                     LVIILALSMMFTINIYMALIALFIIPISYFVSKFVVKKSQSRFSLQQNALGKLNGKVQ
                     EMYTGFNEIKLYGKEEDSIKEFKKVNQELCENGFKAQFISSMMNPMVSLVTYFGIAAV
                     AVVGSIYAVSGGITVGNLQAFVRYIWQINQPLSQMTQLSTVIQSSFAAIERVFEILDE
                     EEEIPDVENPVKIENVKGNVTFEHVNFGYGENSTLIEDLNAEVKSGQMVAIVGPTGAG
                     KTTLINLLMRFYDVKKGAIKIDGVDIRDMKRKDLRSMFGMVLQDTWLFNGTIFENIEY
                     GRFGATKEEIIQAAKVANVHHFITTLPDGYNMFLNEEASNISLGEKQLLTIARAFISD
                     PSILILDEATSSVDTRLELMLQKAMRNLMNGRTSFVIAHRLSTIRNADLILVMNNGSI
                     IEQGNHDELMEKGGFYEKLYNSQFADKESE"
     gene            complement(33020..33328)
                     /locus_tag="PC494_001119"
     CDS             complement(33020..33328)
                     /locus_tag="PC494_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3911639.1"
                     /translation="MFNKIYEKKEFIVFQVKKGYVVYNTRKSFEEGHTHLKHFEAAKT
                     AIDLAINKKIPRSKDGYYLTSLIRISDDGYYIDKLSELLYVREQKGKKEKYCNSGYQM
                     "
     gene            complement(33590..34138)
                     /locus_tag="PC494_001120"
     CDS             complement(33590..34138)
                     /locus_tag="PC494_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3911640.1"
                     /translation="MIFLNEDVVTNETIDKDYAIEEVRMACKHFGDLYFYFSKVLFEE
                     FGEDKTSEILRKVLFERSEERAIAMRERAHENGDELIADNIISTTDVPFLGWVPEFEE
                     LHCPYGASWLLRFEENPWFKKFASLYCDVTDTTVAEVFTGDTSHKITKNILWGDKSCE
                     RIYFHDDKVSEGKYTYGNKNCK"
     gene            complement(34241..34912)
                     /locus_tag="PC494_001121"
     CDS             complement(34241..34912)
                     /locus_tag="PC494_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDF3911641.1"
                     /translation="MATFKRLQEQAYDYLKELILSGKMIENEIYSETKLASEIGISRT
                     PIRDALQRLSQDGFIDIIPSKGFRIHQITANEIVEIFQIRSAIEGFCTFLITSQYKEA
                     RAVETISKLKHLLDKQKDILLGDKNLNSFAEYDTLFHTTIVSYAQNTEFDKMFNNYMY
                     RIKKLALDSLSHEGRLETTLKEHTDIFNNIANGCIEDIYRTTLIHMETPKYINLEDFC
                     NNKLF"
     gene            35308..36213
                     /gene="garR"
                     /locus_tag="PC494_001122"
     CDS             35308..36213
                     /gene="garR"
                     /locus_tag="PC494_001122"
                     /EC_number="1.1.1.60"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxy-3-oxopropionate reductase"
                     /protein_id="HDF3911642.1"
                     /translation="MEGYKMKLGFIGLGIMGKPMAKNLLKDGCNLLVYDINKSAVDEL
                     ISCGAKYASVLEMGQECDIVFTILPNGTIVQDILFGIDGLAKTLKEGSIVVDMSSVTP
                     TESILCANKLKDMGLEFIDSPVSGGEPKAIDGTLAFMAGGKEEIYKKVEPFFNIMGSS
                     SILIGDNGSGSVTKLTNQVIVNLTIAAVSEAFVLAAKAGADPEKVYKAIRGGLAGSTI
                     LDAKIPMIMNRDFKPGGKISINLKDIKNVMQTAHNLDVPLPMTSQLLEIMQTLKVHGH
                     LEDDHSGIAQYFEKLAGVEIKKHDN"
     gene            36349..37731
                     /locus_tag="PC494_001123"
     CDS             36349..37731
                     /locus_tag="PC494_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntP family permease"
                     /protein_id="HDF3911643.1"
                     /translation="MITGYGLLIAFVISIGILLVSIIKFKVNPFLALLITSIITGFMV
                     RMPINEISTTISTGFGNTLGSIGIVIGLGIIFGNILSESRATESIAKGLLAKTGEKNS
                     ALAVTTAGFLISIPVFMDAAFVIMMPIIKYVSRVTKKSLMVFVCALGVGTIVGHALVI
                     PTPGPLAVAANVNANVGSFILYSIIVAFPAALIGGWIYGKRFEKYPAYAIDENDREKN
                     LEQGKDSIKIEDDDSSKVPGFGISMFSLLFPILLILISNVFSMFLEKGSTMSGVLAFI
                     GDKNIAILLGILVAIGFLKKYINKPMGDVVIEAADSAGLILLITGSGGAFGSVINASG
                     IGNFLVDTMSGLSISVVVLGFLLSALLRISQGSATVALVTTSSILGPTILATGMSPVL
                     VGLAICAGGVGFSLPNDSGFWVLSRFSGLSVKDTLNSWTIGGTIAGVVAFIMVLLLSV
                     INGIIPLPGL"
     gene            37802..39238
                     /locus_tag="PC494_001124"
     CDS             37802..39238
                     /locus_tag="PC494_001124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyacid dehydrogenase"
                     /protein_id="HDF3911644.1"
                     /translation="MREVKPISIDILNTFKQVDEDRLNKLLADELKHLDRKIVVLDDD
                     PTGVQTVHDISVYTDWDKDSMEQGFNEKNSMFFILTNSRGFTVAQTTKAHKEISKNIV
                     DVSKKVNKDFIIISRSDSTMRGHYPLETNLLKSEVERLSGKLFQGEIIMPFFKEGGRF
                     TIDNVHYVKEGEILVPAGMTEFAKDKSFGYKSSDIGEWCEEKTKGKYKSSDMIYISSK
                     ELRELNIEAITEKLKKAEGFNKIIVNATDYVDVKVFTIAFIRAVNSGKEFMFRSAAAI
                     TKVLGGVSDKELLTKDELVSKGNTNGGIILVGSHVNKTTQQLEELKNCKYPIEFIEFN
                     QHLVLQENGLKNEVKRVIKVVEEKISRGKTVAVYTRRERFDLDTNDKDKQLMISVEIS
                     DAVTSIIGMLNVRPNFIIAKGGITSSDVGTKALRVKKATVMGQIKPGIPVWMTGKESK
                     FPNMPYIIFPGNVGEISTLRESVEILMG"
     gene            complement(39424..40278)
                     /locus_tag="PC494_001125"
     CDS             complement(39424..40278)
                     /locus_tag="PC494_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3911645.1"
                     /translation="MSTFYIQFLYFVIYSFIGWCCETTYCSVLQKQFVNRGFLNGPFC
                     PIYGFGALAIVATLTPFVHNIPLLFLFSIIITSIMEYCTSFILEKIFNMTWWDYSKHK
                     FNIHGRVCLENSLMFGVLSLIVMLIVHPIVVDFINSISKNVLFIFAISIEIYFVLDLV
                     ITVHTILQLNGKLKQINLIIKELKDKKEYYKLITQETIENKLESLVENRLDTLEDRFE
                     ILKEKENYRYAKNRIDELKNKLNTLLSNHKLLHRRIIKAFPNISSNKHTDILNKIKEN
                     IKSIKKDK"
     gene            complement(40546..40869)
                     /locus_tag="PC494_001126"
     CDS             complement(40546..40869)
                     /locus_tag="PC494_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1540 domain-containing protein"
                     /protein_id="HDF3911646.1"
                     /translation="MERINCNVINCSHNNSHICYADKIFINGEKAHNDRHTCCSSFLD
                     ESIYSNLSSNVNNRNCEELVCTVKNCKYNKDGSLCTLDNILVAPETDRVNLYIETCCS
                     SFECK"
     gene            41072..41701
                     /locus_tag="PC494_001127"
     CDS             41072..41701
                     /locus_tag="PC494_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3911647.1"
                     /translation="MFEKKKKELFPWKISALILVGVFVLSSGVYIGTRLKHNGVQTGE
                     VVSTSANMNEKSKEAFGLNKNCEVWLQSEGENETNYKRTLTMAGIVPESLLDKTKSEI
                     VSYFKKEYPTKKIKSMDKNEIILVESKYSDNKDVQAMDVTIKGKYTIENDNGNIALYK
                     YDDSGSKTLVEKTKIRVDSLPKTVQDEIKKGVVMDTEEEAYSRLEDFAS"
     gene            42029..42538
                     /gene="ruvC"
                     /locus_tag="PC494_001128"
     CDS             42029..42538
                     /gene="ruvC"
                     /locus_tag="PC494_001128"
                     /EC_number="3.1.21.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="crossover junction endodeoxyribonuclease RuvC"
                     /protein_id="HDF3911648.1"
                     /translation="MIILGIDPGIAIVGYGIIEYKNSKFKVIDYGAVTTPAHMNISRR
                     LELVYKGIDTIVKNYNIDEVGMEELFFNKNVKTAITVAQARGVTMLACAHNGKPVYEY
                     TPLQVKQGVVGYGRADKAQVQQMVTSFLSLKKVPKPDDVADALAVAICHAHSNKLEKT
                     LKNIGGKYV"
     gene            42531..43133
                     /gene="ruvA"
                     /locus_tag="PC494_001129"
     CDS             42531..43133
                     /gene="ruvA"
                     /locus_tag="PC494_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HDF3911649.1"
                     /translation="MYSYIKGTVEEIYIDSIVVENNGIGYKINVSSNTIMNLQVGEAT
                     KIYTKLIVREDDMSLCGFVSREELKMFELLTSVSKIGPKVALSILSFASPAQLGAYIL
                     SEDIGKLSKAPGVGKKTAERIVLELKDKVDKNNIEFEPTLLSQKPTLISQDESVDALV
                     ALGYTLSESKEAVQKCKKDGMNTEAIIKKALTYIMSKSLK"
     gene            43240..44259
                     /gene="ruvB"
                     /locus_tag="PC494_001130"
     CDS             43240..44259
                     /gene="ruvB"
                     /locus_tag="PC494_001130"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HDF3911650.1"
                     /translation="MQGFEDENRIITSTMKMEDIDIENSLRPKTLEDYLGQEKSKEQL
                     SIFIEAAKSRNEQLDHVLLYGPPGLGKTTLASIIANEMGVNLRITSGPAIERAGDLAA
                     ILTNLNENDVLFIDEIHRINRSVEEVLYPAMEDFCLDIIIGKGPSARSIRLDLPKFTL
                     IGATTRAGMLTNPLRDRFGVICKLDYYTVDELSKIVLRSSSILDAEIQSNGALELAKR
                     SRGTPRIANRLLKRVRDFAQVRADGKITDKVAKDALELLGVDSLGLDFVDEKLLMTII
                     EKFRGGPVGLDTLAASIGEDRNTIEDVYEPYLLQLGFINRGPRGRVAMPLAYEHLKIP
                     YPNEK"
     gene            44577..45602
                     /gene="queA"
                     /locus_tag="PC494_001131"
     CDS             44577..45602
                     /gene="queA"
                     /locus_tag="PC494_001131"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HDF3911651.1"
                     /translation="MKTSDFKFDLPQELIAQVPIEDRASSRLMVLDKETGNIEHKVFR
                     DIIEYLNPGDCLVLNNTRVIPARLIGEKLETGGKIEFLLLKRTEEDTWQALVKPGKRA
                     KVGTKFSFGNGKLIGEVVDLSDEGSRIIKFHYDGIFEEILDELGNMPLPPYITARLDE
                     KERYQTVYSKHNGSAAAPTAGLHFTEELLNKIKEKGVDIAFVTLHVGLGTFRPVKVED
                     VLNHKMHSEYYMVSQEAADKINRAKENGKNVICVGTTSCRTIESACNEYGKMKETSGW
                     TEIFIYPGYKFKVLDKLITNFHLPESTLIMLVSAICGKDNVLNAYNEAVKERYRFFSF
                     GDAMIIK"
     gene            45614..46099
                     /locus_tag="PC494_001132"
     CDS             45614..46099
                     /locus_tag="PC494_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3911652.1"
                     /translation="MHSLQKQKKNNPILKIAFIFERVLAVVVLIAVFLGTIDVLRLMW
                     GAYIVDFQNPVQYSQLNDFLAQILLLVIGVELVVMLSLHIPGAFIEALLYAIARKMLL
                     LPKNEGMIDVLIGVIAIAGLFAIKKFLVTKDKSALNIMSIHDEEAIKEQQNKEDEDKS
                     I"
     gene            46178..47299
                     /gene="tgt"
                     /locus_tag="PC494_001133"
     CDS             46178..47299
                     /gene="tgt"
                     /locus_tag="PC494_001133"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HDF3911653.1"
                     /translation="MYAVRYELIKTCKQSGARLGRLHTPHGIIETPIFMPVGTQATVK
                     SMTPEELKEIGSQIILSNTYHLYMRPGHELIKRAGGLHKFMNWDKPILTDSGGFQVFS
                     LGPLRKIKEEGVEFRSHLDGSKHFLTPEKAMEIQNALGSDIMMAFDECAPYPSDREYV
                     KNSLERTTRWLKRCKDAHNNTDKQALFGIIQGGMYKDLREQSAKEITNIDLPGYAIGG
                     LSVGEPKPLMYDVLEHTTPLMPKDKPRYLMGVGSPDDLVEGVIRGVDMFDCVLPTRIA
                     RNGTAMTSQGKVVVRNATYAEDFTPLDPECDCYACKNYSRAYIRHLIKANEILGARLI
                     TTHNLHFLLNLMKQIRQAIMEDRLLDFRNEFFAKYGYEI"
     gene            47433..47726
                     /gene="yajC"
                     /locus_tag="PC494_001134"
     CDS             47433..47726
                     /gene="yajC"
                     /locus_tag="PC494_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HDF3911654.1"
                     /translation="MPQQQIIMSIGLWVVVIAIFYFLMIRPQKKKDKQLKEMRSSLSV
                     GDKVITIGGIVANVAKVEDDVVILELGPNRTKVPFEKWAIGTVKSKKEEIEED"
     gene            47784..48146
                     /locus_tag="PC494_001135"
     CDS             47784..48146
                     /locus_tag="PC494_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR04086 family membrane protein"
                     /protein_id="HDF3911655.1"
                     /translation="MGKSNYIFKGLGYAYIITLAVLLVYNLFLTFTDIGGDNITMVSS
                     FITTISAAIGGFYTSKHMKEKGLMYGLLVGLLYIVCIFLTVFLAQEKFVFEIGMIYKL
                     LLISAAGGIGGVLGVNFK"
     gene            48212..48355
                     /gene="scfA"
                     /locus_tag="PC494_001136"
     CDS             48212..48355
                     /gene="scfA"
                     /locus_tag="PC494_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="six-cysteine ranthipeptide SCIFF"
                     /protein_id="HDF3911656.1"
                     /translation="MENKHVKTLSQATLKQSAAKGGCGECQTSCQSACKTSCTVANQE
                     CER"
     gene            48982..50877
                     /locus_tag="PC494_001137"
     CDS             48982..50877
                     /locus_tag="PC494_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp8"
                     /protein_id="HDF3911657.1"
                     /translation="MLSNKKRSMAIVMAGATVMSAAAPIFADNTVTENVDKNYTVSAK
                     DSAKLIEEVRKALEVKFEDTKAGANVNDRVYDIKVDNVNLTNATQLQNKINSLTEGQS
                     LKVTIQDKGHQVLGGKVVDYKIENYKTAQEIVDAVNAYNATLAEDSDNKLTATIKSTN
                     TVEVKRAKDSANVITLNVGDQHLDFSKVITSEEGTFEGYEKSYSDIDSKELHTITVKN
                     ADLQDISAEELFDGIRLTTLGREIVNKVKNGYALTFENEAILTQEQEDSDDKDKPEKS
                     SFDIVLSKANEKPETISVSSKNHKLVRDLHKVLTDVKDGKELKVEVLSGDSRFTTAVE
                     VSKERFKDGEAEAIILVGEDAIVDGLASAPLASQKNAPILLSKKDSLPSEIEAEILRV
                     LGSNLSSKKIYIVGGESKVSKETEEKLSKLGVSKVERVSGEDRFETSLEIAKQLKDTF
                     KTAFVVGGNGEADAMSISARAAQFGAPIIVTGNELDANAEKLLKGKELEIVGGENSVS
                     KEVEDKLVDIDLNNKVERLAGENRKDTNAKVINKYYAGATKAYVAKDGYVGGNGQLVD
                     ALTAAPLAASSKAPIVLTTEELSKSQEEVVELRLKNATKLVQIGEGIAKNAIEKIAEK
                     INLFTKN"
     gene            51339..52742
                     /locus_tag="PC494_001138"
     CDS             51339..52742
                     /locus_tag="PC494_001138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp9"
                     /protein_id="HDF3911658.1"
                     /translation="MKNSKKILAIGLTLFLVMVNTPMVNALTSVEQIKGNDRYETAAK
                     IADKQNYNTAILINSDNSLADGLSASGLAGALNAPILMTKQNQIPNTTMERLNKAKTV
                     YIIGSESTISKNVENQLLSKKKVVQRIFGENRFDTSIKIAEKIKEIKPIDKVIIANGF
                     TGEADAISASPVAARDGVPIILTDGNSVGFDTTGLKSYALGSSEIISDELVKSTNSIR
                     LGGTDRFETNKIVIQEFYKNSKEFYLSKGLQLTDALAASTIAKNAPVVLVENGSNKSI
                     LSGADKLTVLGGINQNVIKQCINQASPNQQGLYYNPNDRAFKERIKGKVYALTKQYRK
                     ENGVRALSVASRLEGLANDWSNLMANKKTLSHTINGKNSYSTFLKYLDWSEIKPGYIA
                     VQGENIIKYKIPDKPVYTNRDADDIGNFIFNEWKTNPEEGTNMLHKGYEIMGFGIAIT
                     GDKNLYATHEFYGRYKE"
     regulatory      52914..52999
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            53123..59086
                     /locus_tag="PC494_001139"
     CDS             53123..59086
                     /locus_tag="PC494_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="calcium-binding adhesion protein"
                     /protein_id="HDF3911659.1"
                     /translation="MKKAISCVLAVSMCSAPLNVFAEPILEGKLRAVEKSVTEKLRGS
                     LEVDLNFSLPIKNSESESMTNMQLRLKDDSNNSGIIKLGEKDSGTVNVGTDNIEYTIK
                     KLSASRSEIKNKDENISYYNIVFNNLPVGKYNVEVSGDGFKNKEIKDIDISSYSQRVL
                     LSNRASVDNKNKPLNYELFLMGDVNGDGKVDKSDYNKVLENIDSNKREFDLNRDGKVD
                     IVDLDYVQKNLGQSEDAKSLESIVSTNPIVDTSKVELKGNSDVDINGNVENLFSGENN
                     GVTISSKNDEISEEKPAVMDIALSEALNMEVINIKAPEGTAPAKGIVEVTDKDGNVQQ
                     IPYENKEYMKNLKDEEQQEEVNNEQEEVNQEEVNNKDENINQTDNNSNNKDENNDKQQ
                     ENSDKQEANSNTNQDKNNDKENSSMDKPNSDEDTPKEEGNISKDDNSTTSTYSRSALE
                     TYADVQNSDIVINLGKQVAVKKITIKITATTANDRNLAEISKVEFLNNVYKEIPKPEM
                     NIPKINKISTSTAVGNEKVSFYWNNEVNVSAYELILDKIDSKGKVLSTKKLQTSKNTI
                     EVRDIEAYGLYRVSIQSLNGDWSSGYKDATPENLDGVPENVDSNYKPIQFSPDSILEF
                     QVVPDTKPEPPEGINVKGKFKSLDVSWKNHKQAKDFDLYYKEKGSNGSWIKYNDKLIR
                     GTSSKIEGLKDNTTYEVRMTATNHLGTSGMSKTYIGTTESMDAPTTPNYRLINTPKEN
                     GGFGIPTNHIVDVVYPDGYDKSEYSDKNPFDKFNVVDGDFTTHWTFPTYNAAEGTNRG
                     PIITFDKSYTMDTFMATPRFDVSDKTINDFEVRYWDENGQLHNLGDVPFETKTDPVNN
                     NKYVMVRLKEPITATKIQVSVCSSYSYKSNISELKFYEYDSIEDDVRNLFMDGLQVEL
                     KEDVTQEKITELKDRLNTPDKASGEYHPYKTVIERELKLAQDLYNDRATLTDVTTVNQ
                     EINKLGKYKDKNGQYTVNSNNLGMQNDWQALGVAARAGDEITVYVGSKSGKTPKLIYT
                     QYYGESGAYKSGEINLNTGKNVIQLSKLHSLDIECGGSLYIRYAEDTPSGGDIKVRVA
                     GATKIPHLNLNGTINDKSPAGVSESKKKIKAYIEELAKYKDAVKGEPYYPGTNVGNSY
                     GYSEKTGVLNTTDIESDKVTLNVPATAVYQEISKGNSDLNTQVDRLYNSMLAWEQIMD
                     LVYSERGVFKTQDLDGNGTVDDNEFNLTKNDMAPKSRMNIKYQRMFIGAFMYASGLHV
                     GVEYGSVPGLMNGVPFQIDDSGKATGGNLFGWGIGHEIGHVTDIGKMTYSETSNNVLA
                     LLAQTFDDKTHSRLEGSTMDKIYEHVTSNSLGIPSNVFERLGMLWQLHLAYDDDFTGS
                     MLKNNSDADLSNDTFYAKISRKYRALSSSDPINSLPKDQMLVAMASSVVEKDLRDYFK
                     AWGVEITPELNSIMDSKNYEKESRKIQYVNDEARRKILNENIASMAKDTKVSASFSDG
                     IQSGSLVKSNKISIDLDVDKDKDKILGYEIIRSDGNYLDGENGTQVKYRTVGFVDAKG
                     NSKTKFTDNISPLNNRAFTYKVVAYDYHLNPTEEFEVGTVKLSDEGKINKSAWSFITN
                     TVSDGDVRTENDSHGPLQNPEIDNIKDNDASTTYKGKIISKAEWNKDPQKDPDINVEE
                     NPYIIVDMKETLPIVGLKYTKPETEARKFSLKGLFNFRKNTSTTYNPLTNYKIQVSND
                     KKNWEDVSQGTFEYGQDLVGGGKDQDNEARVTFNKDGKLWTYQARYVKLISNNKSNIE
                     VAELDIIGPPGDNIEIGIINNADETRTNGIGKLAEDYVYQSDDSSTSEDETGKIPAGS
                     IVITGEYSGNPAFNLPLLIDKNNKTISGEALLFAEVPEKGELGEISKGTWVYYMPKEN
                     FDSLSDKVKAELYRYNDLQGDTPVGQRFVSDTMYVPVGAKNYDELKTISLTDSNSKAR
                     KATRNSIDISNKKVITVSNKVKGNIVRDK"
     gene            59290..61170
                     /locus_tag="PC494_001140"
     CDS             59290..61170
                     /locus_tag="PC494_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp10"
                     /protein_id="HDF3911660.1"
                     /translation="MSKRKSFIRTIAVSTMAVAVTGSATCAYAAPVLQGTKTYEKVNT
                     IDISVDSVENIVYSFQASIKVQGEVEVVDNEQKEKITWSDNIKSQIKSGNANATCRVE
                     YNKSSNTTTLDIYVTSNEDLLDGNRLNIGRISVKKSGSNSNADYKVLGKGTNDKPALK
                     IVTYNNKTVDYENISSDEGLIFTLINESEVKPIGGTGSSKNDPEKYKVEKSEALEYLL
                     NNIRINYSIVSKETQESGSNVILKLGLAQKTTKGRKATINKYVEVTLPKSLEYIVENE
                     LSKPDELPPDNGNGGNNGGGSNSGGSSSGGSSGGGSSSDSTSNVTVKKLKGADRFETA
                     IKISQSGWTKSDTVVIVNGEDKSMVDGLTATPLASVKNSPILLSSNEKLPQKTVEELK
                     RLNPSKVIVIGGNNSMPNSVVEAIKAVNSKISVQRIGGDTRYQTSINIAKEIDKTNNV
                     SKLYIGAGNGEADSLSIASLAGKEKTPIVLTQKDGVDNEAEQFIKSNKVSNIYFIGGV
                     EKISNKAIEQVGKIANKDISNNRVAGQTRQETNAKVIDKFYSQSKLDGVVVANQDKLI
                     DALAVGPLAAKNNSPVILATNTLDKSQESSLKGKNSSKLFEVGGGIASSVIDKIKSLI
                     EK"
BASE COUNT        24103 a         7043 c        10593 g        19547 t
ORIGIN      
        1 tagaagtaat aaaaaaaaat aattaatata aaaatgtgta caaactaatg aatattgata
       61 tagtaagcta tcatatgaaa gagtatgtac acattttttt tactaatttt tcacaatatg
      121 aacataaata atttacagga aaggaatctt ttatgaaaat tcaaaatact gagtggggat
      181 atattgaatg gaaacatact tatgatgaaa ataatccaaa acaagctatg aatatataca
      241 ttgcagtaac tatgcctggt aagaaacatt ttaatcatgt tcattatggt caagagcaga
      301 tgatatatat tttagaggga gagggtttgt atattataaa tggagtttgg aagccatttt
      361 atcaaggtat gattttttat atagaatctg gtagcacaca tgaaactata aatacaggtg
      421 atagagaaat aaaagaactt attgtttcaa ataatgtaga tgatgtagga gagagtgaag
      481 ttatagatat taatcctaat aattatttaa agaagacctt gataaattat agtgaaagta
      541 cattaaattt gtatgcagca gtagaatcaa ttcgtggtca atttatagac ccgtttaaaa
      601 ttccattaat tatatatgat gattcatgga atatagtttt aaaaaatcct tattttccac
      661 ttttttgttt tgaaaaatgt aatcctatga aatttcctca aaattgtgat tgtatgaatc
      721 aaaaaagtag caatcaattt gtatgtgaat atgggataac tatatataat ataccaatac
      781 tgtacaaaag caatagcata ggtgttataa gaggagggta tgtactatta tctgatttga
      841 atttagatac agagcataat aatttatatg atattccaga gggagctgct agaagtataa
      901 aacgcctcct gaaacaaata tctaaaaata taataaattt ttgctctttt aatgatataa
      961 gaaaggattt acaagaaaaa gagaagacta tagcaagaac atatcattat ggagagcaac
     1021 ttgaaatgaa tttaaaagta gctcaagata tggttactaa tttaagaata aatcatcact
     1081 ttttatttaa tacattaaat tcaatggcaa gcatagcgct agatgatggt agttatgatt
     1141 tgtatagtgc aataatagat ttatcaagaa tgtttagata tacaatgagg tctgatttaa
     1201 gatttgtaga attagaatct gaaatattat acattaaaaa ttatttgaat ttacagaaat
     1261 tacgttatgg agatgcactt aaagtaaaat atcttattcc agagaagtta tataaccttt
     1321 ctgtgccttt taactttatt caacctattg tagagaatgc atttacacat ggatttagag
     1381 atattgacac agaaaagcga attgaaataa ttgcaagatt agattctcag tatgctatta
     1441 tagagattca taataatgga actatcttag atggaaataa tatagacaaa ataaaggcag
     1501 gtattcgtag taataatggt catggtttgt ctttaatata tacaaaattc acatctgctt
     1561 atggaaataa ttttgatatg gatataaagt cgagtgataa tgaaggaact tacataatga
     1621 ttaaaattcc tattgaaaat tataaggaat atgtatagaa cttgtgaaaa attaataagt
     1681 tttataaatg ttaagaaata tattagatgt ttttatgttg ttttatatat cttacttttt
     1741 tatattatta agctaaaagg gaggtattct catgagaaga gcactaataa tagatgatga
     1801 agaagctgtt ctaaaaataa taacacattt tatagaaatg aaagatatgc caataaaaat
     1861 tgttggtaaa gcaacatctg gtgatgaagc agtagataaa atcattggtt tagagccaga
     1921 catagttttt atagatattc aaatgccaat atacaacggg ttagaagtaa tagaaaaaac
     1981 atctcattta tctaaaaaaa taaactttgt agtaataact gcatttaact attttgaata
     2041 tgctcaaaaa gctttgagat taaatgtaaa agatatactc cttaaaccat tggatatgaa
     2101 agaatttact aagtctgtag aaaaaattat tggatatcaa tataccaata atgatttatt
     2161 aaatgagata ctggaatata taaatctaaa ctatagcaat gacttaaagt taaatgattg
     2221 tgctagatta tttttaacca atccatctaa tatatctagg atttttaaaa gtaatttaaa
     2281 tacaactttt atatcatatc taaatcatat aagaatagaa aaatctattg agttacttga
     2341 aaatactaca aaaagtataa atgagattgc agaaatagtt ggatataata gcctaaataa
     2401 cttttataaa aactttaaga tagaaaaagg aatgactcca aaagtttata aactgaacac
     2461 taaaaattga aattgataaa taaaaagtca atatagataa ttgtttgagt gtgtctgaat
     2521 aagtatactt taattatgat aaaaattaaa gcgctttaaa catatttaat aatattaaac
     2581 cttataaaag ctgtacctat ttatataaaa aaatatatat aaataaaaag aaaaagatat
     2641 acaaaataaa aaaagtgaat taaatactgt tttaaaaata cagaattttc atttaattca
     2701 ctgagagttt atatttctta aaggaaggta actttataat ggaggtaatt taatatgtca
     2761 gacaaagtga atatgaaaaa tattatctgt attgcaggcg cttatctagc aacagcaatt
     2821 ggttctgggt ttgctactgg tcaagaaatt ctacaatttt ttgcctcaca agggtatatg
     2881 ggtttaattg gagcattaat atcaatggta ttgttttcat ttcttggtgc tgaagttata
     2941 actagaggta gagaattaaa acttaaagaa ccaacaagaa tttacacttt ttattgtggg
     3001 aagattttag gaaaatttta cgaatggttt agtccaatat ttttatttgg gattcttata
     3061 gtaatgattt caggtgcagg ctcaacttta actgaatact atggtataaa tccttactta
     3121 ggaagagtat tgatggctgt tgctacttta attacagtgt ctatgggttt agaaaaatta
     3181 gtaagcatac ttggacgtat tggaccagtg atagcagtat ttacaattgc tgttggatta
     3241 ataagcttgt ttaagcattt tgacggttta tctatggttg gagaagctat gaaaaatatt
     3301 gaagttacaa aagcatcaga aagtccaatc gtttctggtg taatatataa tacattaaat
     3361 attattgtaa tgattgtttt tttaacagga atgggagctt ctattgaaag taaaaaggat
     3421 gctttttggg gaggtttatt aggtggaata gtgtttatga ctgctggtat agttatgtat
     3481 ttggctatga tttcagatat aggaaatttg tatatgaaag aaataccatc actttattta
     3541 gcagataata tatctccgat tgtaggtgta tgtttttcag ttgcattaat attaggtatc
     3601 tatacaacag ctgttccact tttatggtct gtaaccaata gaattgttga agatgaacat
     3661 cctaaattta aattggtaac aacagtaata gctattttgg cttgtatagg aggtttttta
     3721 ccgtttggta aattagtaaa cattttatat ccatatacag gttatatggg gcttttaatt
     3781 ttagtctgta tggtgtataa agcaattaca tgtagaaaaa aatcaacaca aagtcaggaa
     3841 tagagccact tattaatagt ttttatttaa agaaattttt tatataatcc gaatttaaaa
     3901 agtcaaaata gttaaataaa ttgcaaaaca tgataatata tttaattaaa ataatatagt
     3961 aaaatgtaaa tataaactaa aattaaattt ataaaaaata tctttataaa gattattaac
     4021 ttatataatt tgtagttaaa ttataaaaaa taaaaaaata aaattttgga gaggtgttag
     4081 tatgcatgaa cttattttaa tctcagaaaa gtataaagaa gatattttag atttttttac
     4141 agatattcat atgcaccccg aattaagttt taaagaattt aggactacaa aagctataaa
     4201 agatttatta gtaagtttag acatagaaat attagattta ggaatggaaa caggagttgt
     4261 tggattatta aaagggaagt atgatggtcc cacagtagca ctaagaggag atattgatgc
     4321 attgccaata tatgaagagg ttgatattaa gtataaatcc agatatgatg gtataatgca
     4381 tgcatgtggg catgatatac acacgtcttg ccttgtagga tgtgcatatg tattgtctca
     4441 tattagagat agtcttcatg gaaatgtaaa gtttatattt caaccagccg aagaagtcaa
     4501 taaaggtgcg aagatgctag tggaacgagg agtaatggaa aatccaaaag ttgatgctat
     4561 atttggactt cataatcatc cagatatacc ttgtggaaaa ataggtgtta agttaggtgg
     4621 gttaatggca gcagtagaca ctattaagat agaagtaaat ggatttggag gtcacggagg
     4681 tataccaaac agaacaatag accctatagt agcatcaagt gcaattataa tgggtattca
     4741 aaccatagta agcagaaaca taagtccatt agaatcagct gttatatcaa taggtactat
     4801 aaatggaggg actgcaaata atgtaatttc agaaaaggta gatatgacag gcacatgtag
     4861 aagctttagt aatgaagtac gaaagaaaat atcagaaaat ttagaaaata tagtttgtga
     4921 gatagctcgt ggatatcaag caactgcaaa gctagattat ttatttgatt taccagctgt
     4981 tataaatagt aaagagatgt acgcaatagc ttgtaagtct gtgtgtgatt tgtattcaga
     5041 agatgctata gttgatccaa taccttctac aggaggagaa gatttttcta tattcatgga
     5101 aaaagcccca ggattttttt actggttagg ggtaggcaac aaagaacaag attgtatata
     5161 tcagtggcat aatcctaaat ttaaagctga taaaaattct atattggtag gtacaaatgt
     5221 actatgtcag tctgttataa attatatgga taaattaaaa aataaaattt aagataaagc
     5281 attctggaga taaagtttat gagggggtat tagtttgagg aaaattaatt cacaggaaaa
     5341 aaacaaagat agtggattat tgatgagggc actaaatgtt gtagagagag caggaaataa
     5401 acttccagac ccagtaacca tatttttatt actatgtata attgttgtaa tattgtcagc
     5461 agttatatct aatttaggag tagaagaaat acatccttct acaaaagaag ttgtaaaggt
     5521 agtaaatcta ctagagaaag agcagattca atcatattta ggtagcatag ttacaaactt
     5581 ccagtcattt gctcctttag gattagtact ggttacaatg cttggagcag gtgttgctga
     5641 gaaatctgga tttatggaag tgttaatgaa aaagggtata agtaaagttc cacaaaaact
     5701 tgtaactgta gcaatcgtat ttgcaggtat gttatcacat acagcagcag atgtaggatt
     5761 tataatatta ccaccacttg cagcacttgt gtttttagga attggaagac atcctcttgt
     5821 aggtatgttt gcagcttttg caggtgttgc agggggattt gcagcaaatg ttatgcttag
     5881 tactacagat gtattgttag ctggatttac aataccagca gctcaaatga tggacccatc
     5941 ttaccaaggc aatccagcaa tgaatcttta ttttgctttt atatcagcga tagttttaac
     6001 ttttgcagga gcatttgtaa ctgaaaaatt tatagctcct cgttttacaa aatataatga
     6061 ttcaacaaat gataaggata tacaggaatt gagtgaactt gaaaataagg gtataaaata
     6121 cgctttatta tcattgttag ttgtagtagt agtgatagtt gccttatgta taggtgacaa
     6181 tgcatttatg aaagatccag agactggttc tatactatct agtaatgcac ctttaatgaa
     6241 aggtatagtt cctataatca ctattatatt tttaactcca ggattagtgt atggaaaagt
     6301 aagtaagaag ataaaaagtg acaaagattt agtatctatg atgggtagta gtatgagtga
     6361 tatgggtgga tatatagtcc tagcatttat agcatcccag tttattaatt tatttaatct
     6421 tagtaactta ggaacaattt tatcaataac aggagcaaaa ttactagcag agtcgggaat
     6481 acctagctat ggattgataa taggatttat attgctatct ggatttatca atttatttgt
     6541 aggaagtgct tctgcaaaat gggcgatttt agcacctata tttgttccca tgtttatgct
     6601 actagacttt aatccagcat taactcaaat agcttatcgt attggagatg cttcaacaaa
     6661 tccaataagt ccactttttc cgtattttcc agttatattg gcctttgcca gaagatatga
     6721 taaagatata ggtataggta ctgtcatatc gaatatgatt ccatactcag tggtatttac
     6781 attaatagaa ataataatat tgttactatt catgggtatt ggcataccat taggacctgg
     6841 tggaggaata tcttacgttt tatagaccat tataataaat ttatcaatga agattaaact
     6901 aataaaatat attctttaat taagaggagg attattatgt taaaaacaac aaaaatttca
     6961 gacccagagt tatacaagat tgtagctgat gagttggtta gacaagaaca caatattgag
     7021 atgatagctt ctgaaagtac agcaccaaca gaagtacttg aattaagtgg atgtgtattt
     7081 acaaataaaa cagaagaagg ctatccaggg gctcgttttc aagcaggttc tgaagaagca
     7141 gataaacttg aaaccctagc aataaaacgt gcaaaagaag tatttggagc agaacatgta
     7201 aacgtacaac cgtattcagg ttctacagct aactattgtg tatattcatc aatattaaaa
     7261 ccaaatgaca ctgttttaag tatgcgtctt gaccaaggtg gacacttgac acatggtagc
     7321 gcagttaatt ttttacatga catttataaa tatgaatttt atggggtaga cccaaatact
     7381 ggacgtatag attatgatgc tcttgaagca aaggcaaaag aatgtagacc aaaacttata
     7441 attgcagggg caagttcata tccaagatta atagattatg aaagaatatc aaaggttgca
     7501 aaagaagtag gagcttactt tatggtagat atggcacatg ttgcaggatt agtcgcagcg
     7561 aaagtaatac ctagtcctgt accttatgca gattttgttt cttcatctac gacaaagact
     7621 ttctgtggac caagaagtgg tattgtactt tgtaaagcag aacatgcaaa gaaactcgat
     7681 aaaggtgttt ttccaggaac attagggtct atacatctta atacagttgc agcaaaagcc
     7741 ttttcactat tatatttaag tacagataaa tttaaaaaga taatggagca agttgtagta
     7801 aatgctcaga ctctagcttc tgaactgatt tcacatggtt ttagtattgt aagtggaggt
     7861 actgataatc atatagtaat ggttgactta agaagtaaga atcttacagg aaaacaattt
     7921 gaaaaagctc ttgaatatgt aggaataaca gttaataaaa atgttatacc tgacgaccca
     7981 caatcaccat ttgtaactag tggtgttcgt ataggtctta catcaatatc tcaaagaggt
     8041 ctgaaagaaa aagaagttat acagatagca gggataatga ataaggtagc agaaaatatt
     8101 gataataaag aagtattaga tgaatgtaaa gcagaggcac aagaacttat atctaagttt
     8161 ccattatatc cagaagggta ttttgaagat taaatatttt gatttgtata gctcacaatt
     8221 tataaagcct gtaacataaa atttaataat atataaccac tataaggtgt tgattaatca
     8281 acaccttatt ttttttgaaa agtaatatac aagctatcat aagcatataa ttccttatag
     8341 ataattaaca agggggataa agttatgagg tattataata aacctaccaa agaagtatta
     8401 aaatacttaa aaacaaatcc agaaattgga cttgatgata atgaggtaga agaaaggaag
     8461 cttagatatg gattaaatga atttactata aaagaaggta gaacattttg ggacgagttg
     8521 ggagaaagtt tgacagaacc tatgatatta attctcatag gagcagcagt aataagttct
     8581 tttgtgggag aattacatga cgcattaggt attttagggg ctatttttat tggaatttct
     8641 ataggcataa taactgaagg aaaatctaaa aaagcagctc atgccctgtc aaaattaaca
     8701 gaaaatatag aagtaaaggt gcttagaaat gggaagataa ttaaaatatc aaaaaatgat
     8761 ttagtaccag gagatattgt atatatagaa actggggata tgataccagc agatggaaga
     8821 cttatacagt ctataaattt gaaacttaga gaagatatgc taacaggaga atctgatgat
     8881 gtagctaaga atgctgatgc tgtattagat atggaagtag tttattctaa aacagaaata
     8941 atcgaacagg atgcaatacc tgcaaagcaa gtcaatatgg tatttggagg gactcttgta
     9001 gcatatggta ggggcataat ggttgtcact catactggtg ataagacaga gatgggtaag
     9061 atagcacaga atttatcaaa tgaagaccag caaactccac ttcaaattaa attagggaag
     9121 ttgggtgcta aaatagcagg aatatcaggc gtaatagcta ctttattatg tatgtttatg
     9181 attatacaga tgcagagaaa aggtatgtta attttagata caagcagtgt attatctttc
     9241 ttacaatcat tagaacctgc taaaaatgca tatatggttt gtattgcatt aatagttgca
     9301 actgttccag aaggtttgcc aactatgata aatattacct tagctataac aatgcaaaag
     9361 atggcaaaga taaatgcatt agtaacaaag aaagaagcct gtgaaactat aggttctgtt
     9421 tctgtaatat gttccgacaa aacagggact ttaacacaaa acaaaatgat ggtagaggta
     9481 gcatatgttg atggtaaata tataagtgga ggagagtatc aaagtaatag ctattttgaa
     9541 caaaactgta tagtaaattc aactgcagat atagaaaaag aagataattc atttaaatat
     9601 ataggaagcg caacagagtg tgcattactt ttatatcata atgataagaa ctataatgaa
     9661 atgagaaaac aaacgtattt gatatcacaa ataccattta gttcagaaga aaagaagatg
     9721 tcaacattaa ttcgtcaaga ggattcagat atattacttt caaaaggtgc tccagaagta
     9781 ttattaaaaa aatgttctta tgtacaacaa ggaaaaaata ttgttccaat aactccaaaa
     9841 gtagaaaaaa gtattttaga tgagattaag aagttacaaa ttaaatctat gagaacatta
     9901 ggatttgctt ataaaaaaat gagtaattct aaaacagaag ttgcagtgac ttcagaaggt
     9961 gaattgaatt taataggaaa ttcaagaagt tatatgaagg aagataattt agtttttagt
    10021 ggatttgtag gaatagtgga cccattgaga gaaggggtca aagattccat tgataaagca
    10081 tttaatgcag gcgtagatgt aaaaatgctt acaggagata atataaatac agcaacagct
    10141 attggaaatg aattaggatt attaaatgat gggaaaaagg cagttgaagc aacatatata
    10201 gatgtattga cagataaaga attgagagaa gaaatcaaag gaatatctat tgttgcaaga
    10261 agtaaaccag atacaaaaat gagaatagtt tcagcgcttc aaaaaagtgg cgaagttgta
    10321 gctgtaacag gtgatggtat aaatgatgcc ccagcactta gtcaagcaga tgttggaatt
    10381 gcaatgggta tttcaggaac agaagtatct aaaaatgcag cagatataat attgactgat
    10441 gatagcttta gtactatagt agagggaata aaatggggaa gaggtatata tgagaacttt
    10501 caaagattta tacagtttca gcttactgta aatatagtag catttataat tgctataata
    10561 tctcaactta ctggtaagga tatgccattt actacaatac aattattatg ggtaaatata
    10621 ataatggatg gtcctccagc cctagcatta ggattagaac ctgttagaga ttatgtattg
    10681 aaaagaaaac caataaatag acattctgga ataatagcta ggtctatgtt tgtaaatatt
    10741 attataaatg ctattcttat aattacaatt gtatttactc aatcagcttt taatatattg
    10801 ggagctacat cagaagaaca aggtactgtt atattttctt tatttgcatt cagtgccctt
    10861 tttaatgcat taaattgtag agagtttggt ttaaatagta caataccaaa tttctttaaa
    10921 aataaactgg cattgcaaat aatagtagtt acagggataa ttcaaataat atttacacaa
    10981 gtgttccaga gtttctttaa ttctgtttct ttggactttg atatgtggat aaagataata
    11041 ctatttgcat ccactatcct attgtcaaat gaatttgtaa agctaattct tagaacaatg
    11101 aaaaatagta gaactatgaa ctttaatagt aaaaattaat tcctatgaaa ccgcaaagta
    11161 ctatatattg taactttgcg gtttttgttt gtttaatgtt gttttatatt accattttca
    11221 tatttaattt tttattaatc taaacacaat cttccattgt aattgcttca tctgtgtcaa
    11281 cacattcaaa gtcaatatct aatttttgta atattttgta tgcctctttt tgcaaaggag
    11341 tatcaaattc aataggtgat tttgtgtaaa tataactgat aaaaaacatg atttatttca
    11401 ttcctttcca tttaaaaact tatagttata gtgtatcata aggttataaa atatagataa
    11461 atatagtata aatttaaaat atgtacagac aaaacaaaaa aatcatattc taagtaatac
    11521 ttgggaaaaa tgatattatc ataataaata atctttgtaa aaacttatat agaatctatt
    11581 aaacagacac taagccataa aaactttact aaatataaaa ttcgtatcta aatagatata
    11641 tagaataata ttttactgaa gtagagtgat ttttaagaat tttatatata aattatgtta
    11701 tcataaataa agatatagat tataaaattt gttaataaaa taaagggcag ggaggtaagt
    11761 ttcatgtttt ccaaaatctt agtcaaaaca tttatcagag atagcgaaaa cgttcaaaat
    11821 acagatgtta gaaataagta tggttatgta gctggtgtag taggtatatt atccaattta
    11881 cttttatttg tgataaaggt attcatagga atgctcacat ctagtatagc tataatggct
    11941 gatgcattta ataatctttc tgatatggca tcttcagcaa taactatgat aggttttaaa
    12001 ttagcaagta agccagctga taaagaacac ccttttggtc atggaagaat agagtattta
    12061 tcagcattaa tagtagcatt tatggtgatg ttggttggac ttcaatttgt aaagtcatct
    12121 atagaaagga tagtaaatcc aattcctgta aaatttgaag taataccact tatactttta
    12181 attgcatcta taatgattaa aatctggttg agtcgtttta ataaatttat gggaaataaa
    12241 attgattctt cagccttaaa agcagtttca cttgatgctt taggagatgt atttacttca
    12301 agttgtgtag ttatatcatt tattgtagct agatttacta attttcccat agatggatat
    12361 gttggtatcg tagtatcatt agtgatactt tatgctggtt tctctcttgt aaaagatact
    12421 ataaatcctc ttttagggga agcaccggat gaagaaatgg taaattctat tatagagcta
    12481 ttgttatctt ataaatatat aataggtaca catgatttaa ttattcataa ctatggagtt
    12541 ggtagatgta ttgcatctat acatgcagaa attccatcca acatagatat aatggaaata
    12601 catgaaatta tagatactgc agagagagaa atatctgaaa aattagatat atatctagta
    12661 attcacatgg acccaatatg tcttgaagat aaagaagtta tgtcagccaa aaaagaactt
    12721 gaagaaatac ttaagaaaaa tagtcttgta aaatctatgc atgattttag aatagttgga
    12781 aaaggaagca agaagaattt aatatttgat atagtagtta atccttccga attttccaaa
    12841 aacatgtcag aagatgactt aaaagaagat ataacaaaat tagttaagga gataaatcct
    12901 gaatataatt gtgtaattgt tgtagataag gattttattt aattattaat taatctcatc
    12961 ataaggtaaa aaatgtaaaa aggatagaca atagtataga ggcataatat aatagaagta
    13021 tataattgta tttttaatat aaataaagca attttaattg tttttatgaa atattataga
    13081 gatgttgaag tatattctat tattgggcac cttatggata tactgagtca gtggtgcaac
    13141 cggctatgaa tataaattta tttattttca tagctttttt tgtataattt tttagtaaaa
    13201 attactttat atacaatatt aatggaagat tagattataa attataggta acctaaaggg
    13261 gtgagattta catgaagaaa ggaaatagaa aggcattatt aattagttta attatgattt
    13321 taagtatggt ggtgtctaca atatatccaa ctgtatctta tgcttcagaa ttaggagaga
    13381 atagtcagat tcaaagtggt tcaactaatt catcaactgg agaggagaag gaaagcgaca
    13441 ataaaaagcc agaacagact ccagagaaag ataaggcaac agataataaa aaaccagaac
    13501 agaccccaga ggaagaaaaa ccaacagata ataaaaaacc agaacagacc ccagaagaag
    13561 ataagtcaac agataataaa aagccagagc aaactccaga aggagaaaag ccaatagata
    13621 ataaaaagcc agagcagata caagaagaag ataagtcaac agataataaa aagtcagaac
    13681 aagctttaga agatgaaaaa ccactagaca ataaaaatac agaaaaaact ccagaggaag
    13741 ataatctatt agaagatgaa aatttattga aagttttaga agaagaactt aatgaagaaa
    13801 atgaagacta tggatttgtt gtaaaaatta ataacaatac aatagaaacg gagtcaatga
    13861 aaaaaatatc atttaattta acttatactc caacatcaaa aggaatacaa gcaggagatt
    13921 caataacttt taaggtgcca gatgtattca ataaagttaa tttagattat acaagtgaat
    13981 gctttgataa aacagaaagt aatggagagt atacacttac atttagagaa ttacctaatg
    14041 gccaaagtgt aatgcaaggt aaaataggtt tggaagcata tgttaaaaag gttgatgaag
    14101 atactaatgc aaaaatacat attgaaacta ctggaaaaat agaaagtgga agtggagata
    14161 tagatgtaga aataaaacct ggagataaaa cggatgttcc agatgctaaa ggaacactta
    14221 aaaagcttgt tgaaggaaaa aaatcaacta ctgtatttat gccagttaaa aataaagata
    14281 taaattacag tatacaagta aatgaaaagc aggaagagtt aaaagacatt attttgtatg
    14341 atgagcttcc tgaaggattg acattgataa atggttctgt aagtgtagta acaagtgatg
    14401 gaaaagaagt tagtgatttt aatattgaac agagtaaaaa ttctatttca gttaattttg
    14461 gaaatataga taaatcgtat actgttaagt ataaggctag aatcagtgac aaaaatgcaa
    14521 aacatggtaa taaatataag aatgtagcta ggattgaatc tgatggtaag aagatacaag
    14581 aagatgatgc tactgtaagt atatttgata gaggagatga ttatcttctt actaaaggac
    14641 attcaggagc aacaaatatt actcaagttg gtcaagtaat aaactatcag atttcaataa
    14701 atgatgataa atcaccaata agtaatgttg ttataacaga taatatacca gaaggcatga
    14761 gattaactac ttcaggagaa gctgggcatg attttagagt tgtagaaatt ccaatgaatg
    14821 ggagctggac tccttggagt aaagaaaaaa ttgccaataa tatttcatat aaagtagaag
    14881 aaaaaagaaa tgaaagtggg caagtagata aagttataac tggatttaca attaatctca
    14941 gtaaagaaga agtggaatca aagtttttta tagcttatac attaaaggta attagtattg
    15001 aagatagcta tataaataga gctgttcttg atgcaaataa tagtgaaatt gataaaaatg
    15061 atgagataaa ctttaagaaa aattctggat taataagcgc aaaaaaagaa gttgataaaa
    15121 aagttttaaa cagtagtgat aaccagattg ttaaatacaa aatcaatatg tcaacttatg
    15181 gagtttatga tgcaggacaa gtaaatcttt tagatgaagt aaactcagtt ctagaaatat
    15241 ctaatataaa atattctgat aatcttgaac ttaaaaaaga agctggagat ggaaaaaata
    15301 caataagatt agtaaataaa tacgaattta aacagataaa agaaggggaa cctgtgcaaa
    15361 gttgggttac atttgatgca aacttcacaa atgtaaaagt tggggagact atacgaaatg
    15421 tggctcagat taatggttca agtcctccag gagtagagac tactaagcaa ggttatgctt
    15481 ttgaagctaa aaaagtggat gctttagata aaaatgtact ttcaggtgct aagttcaatt
    15541 tagaagatgc atttggaaat atagtagtta aggatttagt tagtgatgaa gatggtataa
    15601 ttcaatctag tgtaaaaaac ccaggaacat attatttagt ggagataatg gctccacgtg
    15661 gatatgaaaa actgaaggat aaagttaagg ttgaaattgg taatgaagat attggtaaga
    15721 tagtagatat tgggaatata gaaaatctaa aacaagaaaa tccaccagta aatccaccaa
    15781 tacctccaga tacagatgaa ccaatagtaa atccaccagt accaccaagc acagataaac
    15841 caaggaaacc atcaagttca tctgatacag agaatactat agttataaat ccaccagtac
    15901 caccatcaga agatataata aatccgccaa taccagaggt attgaatccg ccagtaccac
    15961 catcagaaga gatgatagaa actcctgtta aacagattat tccaatacca gaagtagtaa
    16021 agccatcagt gtcagaagaa aaaaataata aagttaaaga tgatactttg gtaaatccac
    16081 cagtaccacc aaaaacaggg gatagtacta caattattgg agaaatactt ttggttatag
    16141 gagctattgt aggacttatc gtattaagaa gaaataaaaa tacaaattag accctaacat
    16201 tataaaaata taagttatat taaaaaatat cttctaaaac aatatttaat aatgaaaata
    16261 ttgttagaag atattttttt ttgaagattt atgtaaaaaa ataataactt tttagaaaaa
    16321 agttccaaag ggatatagac aattaaaaag atataagcta taatataaat ataaaattaa
    16381 atgaggcaaa actagggaaa cctagtcacg caaagctata ggggctaaag tttagtaaac
    16441 catgccagcc agttgccgaa aagagtaaaa atttcttttt gtatatacaa agatactctt
    16501 gggtatcttt tttattttga aatttattac tcccggccta actcaaagga gggaataata
    16561 tgagaccaag taaaaaatta ttaatagcta taatatcaat attcttaata agttcagttc
    16621 cagtaagtgc acatgcagat agtactacta tacaacaaaa taaagacaca cttagtcaaa
    16681 tagtagtttt tccaactgga aattacgata aaaacgaagc taatgctatg gtaaatagat
    16741 tagctaatat agatggaaag tatttaaatg cattaaaaca aaataactta aaaataaaat
    16801 tattaagtgg aaagttaaca gatgaaaaag aatatgctta tttaaaaggt gtagttccta
    16861 agggatggga aggtactgga aaaacttggg atgatgttcc aggtttaggt ggaagtacag
    16921 tagctcttag aataggattt agtaacaaag gtaaagggca tgattcaata aatttagaat
    16981 tacatgaaac agcacatgca atagaccata tagtattaaa tgatatatct aaatcagcac
    17041 aattcaaaca aatatttgct aaagaaggtc gttctttagg taatgtaaac tacttaggtg
    17101 tatatccaga agaatttttt gcagaatcat ttgcatatta ctatttaaat caagatacaa
    17161 atagtaagtt aaaatcagct tgtccacaaa cttatagctt tttgcaaaat ttagctaaat
    17221 agagttttaa taaatttaaa ataaatataa ataaagagat gctattataa tagcatctct
    17281 tttatattgc gtttaaatct aataaatttt gtcttatgta taactatgat agattatcaa
    17341 ttactactcc ttatacaagg cttcaacgtg tttattatgc atttgagtaa ttatcgtagg
    17401 tataatagaa attattgaac caattactat caataaaatt cctataacca tgtttatagg
    17461 gataatttct ttaagtatta ataatgctag tattggagat attactggtt taaagaagaa
    17521 tactaaagat gtaagactag tagatgtagc ttccattgcc ataaagtaaa gcgcataacc
    17581 aacacctgta acaaatacga atacataaat cataatgggc atattgtgta aggtatatcc
    17641 actaaaaata gggatatttg caaatacatg aagcttattt ttatttaata tatctgcgat
    17701 aaaattaatt ttagtgagta aaaccaatat caacatttcc aaactaccaa atataaagct
    17761 aaagcaggtt acaactattc caccaaattt taaggttttt cttttaccaa atacagtata
    17821 cattgaaaaa ataatagcag aagataatgt taagaatatt ccactaagag ttagttttgt
    17881 atgcaatgga tttattataa ctataattcc aagaacttct aatataagtg aaattacatt
    17941 gtgcctatat attttttcct tcaaaattaa gtaagctaaa agcattacaa agactggatt
    18001 acaactgaac aaaacagcaa ctacagatgc ctttgtgttt agaacagcaa gttgatacaa
    18061 tgacatactt actactacac acataaaacc taaaaatgca aagtatttta agtctgattt
    18121 tgtaatagaa agactaagag ctcttaatct ttttacagca aaaggtagta agactaaacc
    18181 gccaacaaaa aatcttgata aagttatttg taagggatta aagtcattag tgacagtttt
    18241 tagactaatt tccattgaac taaaaaataa ggtagtcagt attatataaa cataaccttt
    18301 tttcaagtca aacacctcct tgtaatttat attagtacta tagataagaa tattcaagca
    18361 tattggaata atatggtatg tataaaatat agtacataaa attataaact accttaatat
    18421 agaatgtaag tattctatac taaggtagtt aattatttga attactttga tttagttatt
    18481 ttaaattata taatttggct aatttttcaa atgctggtaa agaactttta actttatcat
    18541 aagatacaca atatgatact ctaaaatgac ctggacaacc aaaagaagaa cctggtacta
    18601 ataataaatt aaattgtttt gcatcattgc agaatttttt atcatcttca attggagctt
    18661 ttgggaacaa atagaatgta ccattaggtt taacacaaga atatcccata tcgattaaac
    18721 tattatatag aaggtcaaaa ttctttttat aaatatttac atcaacttct gcatctaaac
    18781 ttcttgcaat aaccctttga aaaagagaag gagcatttac aaatccaagt attctatttg
    18841 caacatttaa tgaagacata acatcatcaa aatcatccat ttgcccatta gcaacaatat
    18901 atcctatacg ttcaccaggt agagataatg atttactata agagtatcct ataaatgaat
    18961 ttctatagta ttttagtaca caaggaactt tagcaccatc ataaattatt tctctatatg
    19021 gctcatcaga aattaggtat atgcttgtat taaattcttt ttgttttgaa tccaataatt
    19081 ctccaagatt ttttaataat tcttcagaat atatgacacc agtaggatta tttggagtgt
    19141 ttattattaa agctcttgtt tttggagtaa tagcattttt tagagcatct aaatctggct
    19201 caaaagtctc tatatttgta ggaacttcta ttaattttcc atcatagttt tctgtataat
    19261 ttttatactc accaaaatac ggtgcaaaag caataacttc atcaccagga tttaaaagag
    19321 tttttaaaat aatatttaga ccaccagcag caccacaagt cataattaaa ttttctcttg
    19381 taagatttaa tccatctttt ttatttatgt gttcagcaat agcatctctt acatcctcat
    19441 atcctgagtt gttcatatat ccatgaacta aatttggaga ttcttcattt aaaatatcat
    19501 ttataactgc tttaatagtc tctggaggtt caacacttgg atttcctata ctaaaatcaa
    19561 aaacattttc ctcaccataa atatcagaaa gtttctttcc ttcttcaaac atagctctta
    19621 taacagaact atttgcaact aaagtttgca ttttattaga tatcatatgt aacactcctt
    19681 tttatagatt tatattgctt atgtatatat taccatattt ttactgaatt tagacaattt
    19741 tcgaaaaatt acttgtttga aaatataaac ttttatataa aatatattta tgtacagtgc
    19801 atattaaaaa ttccaatttc taattttatc atgattattt tatataatag ttttttaaag
    19861 aattaataaa acatagattt agagaataaa atattcttga ctatattaat tgtttaatat
    19921 aatatagttg atatagtcaa acatattata attatagaag ggaaatttaa gatggatttt
    19981 aaaaatttac agtatgaaag tttgtcatat attatttgta acttgcaaaa aaactttaaa
    20041 ctttattgtg aaaaatgttt aaaaccatat aaacttacga atggtctata tttctattta
    20101 atttatatta ataaaaatag gaattgttct ttgaatgatg tttctacaga atttgaagtt
    20161 gataaagctc atacaacaag aactatatct aggttagaac aagatggata catagaaaaa
    20221 atccaaaacc ctaatgatag tagagctttt cagttgagag taacagataa gggtgaggaa
    20281 gtattagggg atataaaaaa catattttca aagtgggata atcacataaa aaaagagttc
    20341 tcggatacag aatataaaga actggtaaag aatttacatg tggtaaagga tataaaaaca
    20401 gctgtggagg aagaatagga tgtattgtaa tttattaaaa ccaattaaaa ttggaaattt
    20461 ggaattaaaa aatagagtat cttttgcacc tacaagcatg ggtcttaaat tggaagaaaa
    20521 aattaaaaag ttttctgata ttgctaagtc aggagtagct ctgattactc taggagatgt
    20581 atctattaga cctagttttc ataaggtagc tataagccta tcggatgaag atggagtcat
    20641 taaatacaag aaaattgtag atgaaataca caattctggt gcaaaggtat cagcacaact
    20701 attttgttca gattatgatg ttaatttaat taaagatact atgaatatgg gaattacttc
    20761 acatgatgag ataaaaaaaa taatgaatga cggagtaaaa gattacataa caaatatgcc
    20821 caaagaagaa attaaaaata ttataaattt atttaaagta acagcattga atgcaaaaaa
    20881 agcaggtttt gacatgattc aaattcatgg tgataggctt gtaggaagtt tttcatcaag
    20941 tatatttaat aatagaaatg atgaatatgg tggaacgtgt gataatagaa gtagatttgc
    21001 aagcgaaata attagtagta tccgagatga agttaaggac attccaatag actataaatt
    21061 tgcaataaga caagaaaatc ctcattatgg aaatgcagga gttttacttt cggaagttga
    21121 gtattttgtt aaaaaatttg aatccctagg tgtaaacagt tttcatgtaa cacttgcaaa
    21181 tcattcaaaa ttagaagata ctataccaac caataatcat ccttacttta aagatgaagg
    21241 ctgtttttta tatttagctg atgaggtaaa gaaacacaca aatcttccag tatgtggggt
    21301 tggaaaattg tctagcccag attttataga aagtattatt tcaaataata gagtagatat
    21361 ggtttctatg tcaagacaat tactagcaga tagtaattgg ttacagaaag taaaagatgg
    21421 aagagtagat gagattaaaa agtgctgtta ttgtaataag aagtgtgcag atgctttaca
    21481 aacacgctct cagtttggat gtatactaga ttagaatatc cttataaaaa taaataattt
    21541 gttaaggtta atatattttt ggtgatttag ataaatattt agataaagag gaggagacat
    21601 catgaaaagt ttagttttat attcaagttt aactggaaat actaaaaaga ttgcttatac
    21661 tatatatgat gaaattcaag aagaaaaaga cattaaagat gtaaatgaat tagttgatta
    21721 tggtattgac tatgaaaatt atgatatagt attcttaggc tattgggtgg acaagggaat
    21781 ttgtgataaa aattcaaaac aagtgcttga aaatattcac aataaaaaga tagcactatt
    21841 tggaacaatg ggagcaagta aaaaaggaag ttatggagct agtataatag aaaagataga
    21901 atcaattatc ccaaaagata atgaaatact aggttcattc atatgtcaag gtaagatagc
    21961 agaaggattg aaagcaaaat ataaagagat gttaaaactt tctcctgaca acgaacatat
    22021 tcgccaacaa ttaaataacc atgaggaatc tcaaagtcat ccagatgaac aagaaatata
    22081 tgaagccagt atgtttgcaa aaaatatgat gattaaagct agtattgtgt agtagttaaa
    22141 caataagttc atataagata tagaataaat aatttagtaa aaaagtatag caaataattt
    22201 gctatgcttt ttttatgaaa tcaaaaaaat aataaaaata cttgactgta aaccttgttt
    22261 atacattatt ttatagaaaa taagatagtt ttaaatataa aaaaagatat attattgaaa
    22321 ggagatatta ttgtatgaaa acttataaaa gataattagt ttgattttaa gatatactaa
    22381 atatacaatt ttatagagtg aaaatattta agactatatt atagttataa attaatagaa
    22441 tagagaggta gtgtttaaat tgcaataaca gtatttccaa agttgccacc tcaaattcct
    22501 atccaatgga ataatggtgt agctaattat gtagataaaa aatttattta tgcctaccct
    22561 gtcatttgtg ttgtattcag aatcctttta cgtccattta tatggagatg gttacaaata
    22621 catgctttta tagtgatact attgcagatt atttaacgaa ttttatgtgt tttgtagcgt
    22681 tgtctataga aatattctct atatttttta tttacaatat tgccagacat gttacaataa
    22741 ttatttttat agatatactt gtatttattg ctttactgat aataggtgtg tataaattat
    22801 ttaaaaaata caattaattt ttaaaaataa gtaataagtg atagtgtaaa aagtagccac
    22861 tgcaaattat ggattgtagt ggctatttta ttatttgtat atgaaattat tttgtttttc
    22921 taataagtta cgatatatta tggtttattt cactgataaa aggtttaggt attttaaagt
    22981 aaaaagttgt atattctaat aaaatttaaa cattttgatt ctttaaaatt agagaaaata
    23041 cattgctttt attaaaaaat taaatattaa gaatttaatt tctgcatctt atttagaaaa
    23101 gataagaaat caactttata tatttttttt ggccttcctc tttgattatc gagttttgta
    23161 tttacaatag ttgcaattcc tgctttatat aagatactca atattctatt agcacttcta
    23221 agagttatgt tcatatagtc tgctaatatt tctgctgaca cattatttga atttctatca
    23281 ttaatcatac acatgatttt agatacattt gtattagata gaggtataaa agaagcaact
    23341 ttattggcta ttgagctatc ttcaatatta ttagaatttt tatttgaata taaaggacct
    23401 attgtatcat tagtatcatt tactataaaa gtacagtttc cattcaaaga agcagattta
    23461 ccattagctt gacgagcatt ttgctctgca tgaatatttg tatttccaat gccccaacct
    23521 atatttaagc tatatttaat ttcttttaaa tcttctgaaa taaaaaaatc tgtatagtta
    23581 ttggtcatat tgtttaacat ttctttagta gtgtgtatct ctattttcat atcatttttt
    23641 ttgacctgaa ctccatagaa tccatgtctt gatagagaat ttaatatagt gttatatatt
    23701 tgattttgta tctcatcatt tttaaatatc aaatcttcat ttatgtactc tgaactattt
    23761 actgtaacta tacaagttgc agatttattt ttgtctaagt tttgtaatgt tatttcattc
    23821 accaaagatt taaatgtatt caggattgat tctgtagatg gaaccatgta aatacaatca
    23881 tatccaagct tattaagttc acaactaatg atgtaatttc tagtaaaaga aaggttaatc
    23941 ttattatctc gcaataagtc taaatgtatt tccaataatt tatcatttaa ttttttaaag
    24001 tcatatacag gttgagggat attaaaatct ttaattgtat atggacattt attagagtct
    24061 attaatgaat atatatcata ataattgttg tcctctctta aaaaatccat aaatgatttt
    24121 gtaaagtcaa tatctttttg gctatttaat aatttgaata agtatttata aaaatctctt
    24181 tcatcaagct ttaaaaaatt taatggaact tttatgtctt ttatatttat tataagttca
    24241 ctatatggaa ctataccact gcatacaaat ccatcaaaat tatctacttg ctcatagtat
    24301 atattaggta aattattaaa aggattctcc cctttaagct caataaatgt aatttcacaa
    24361 gtatcattta attctttaag agcttgttta aacttatctg acataaaata agatgttgtc
    24421 aaaaaaccaa ttttatattt cataaaacct cctttaaaat ttcgagagta ttgtaactaa
    24481 tcaatcaatt tataacctca ttttataata gtagataaaa cgcgtcaatt tattttacaa
    24541 aaggaaaatt gaaagaaaaa tcagaaaata taaaaaaaga ctgaaaaata tgttggctgt
    24601 caagaataat tgtgctattt tgtaattaag gactagtctt ttaagatttc ctaaaataaa
    24661 cttagatttt aggaaagaaa tacattttat ttgaaaataa aggagaagat tatgaataca
    24721 tatttaaatg aaatttctaa gtttgttgat gagaatagag aagaaatagt ttcattatgg
    24781 aaagagattg ttaatatgga aagctataca cattgtaaag aaagcgtaaa taaattggct
    24841 aagagattaa agtttgagtt tgaaaaagaa ggtttagatt gcgagttagt agatgttgga
    24901 gataatggta gtacattgat aggtacactt ggttccaata tagataaaaa gccaataatt
    24961 ttttcaggtc acatggatac tgtctttgaa acaggtacat ttggagagaa tccatttaaa
    25021 ataatagaag gaaaagcata tggcccaggt gttttagata tgaagggtgg tataataatt
    25081 tccttatatg ttattaaagc tttaaataaa ataggataca aagaaagacc aataaaaata
    25141 gtattttctg gagatgaaga gataggacat aaggattcaa caggtgcaga tgttatattg
    25201 agggaagcaa aaggtggtct ttgtgctttt aatatggaaa ctggattagt agataatagt
    25261 ttgtgtgtag gtagaaaagg aagaatagga tgtaatatac atgtaaaagg tgtagaaaca
    25321 catgcaggta atgattttga aggtggaaga aatgctatag aagaaatggc taataagata
    25381 ctacgcatac aaaaattgac taatttagat gttggaacta cagtaagtgt aagtgtgatt
    25441 aagggtggaa gagtggaaaa ttctattcca gaagattgta gtataaaagt agaccttaga
    25501 tttgaaaaag tagaagaaat ggagaatgtt aaagaacaag ttagagagat atgtaaagaa
    25561 acttacatag aaggaacttc tacagaagtt aattttataa gtgaaatgat gccatttgaa
    25621 actacagaag atgttatgag atttcataca tttgtaaatg aagtgtcaaa ggaaaatgga
    25681 tttggagaat taaatgctaa gagacttgga ggtagttcag atgcaagtta tttaactatt
    25741 gcaaacgttc ctacaatctg ttcatttggt gtaagagggg aatggaacca cacatcaaga
    25801 gaatatgcag tagtaaattc tatgtttgag agggtgaaat taatttctac agttatttta
    25861 aacttagata aatttgaggt ataaaggggg attttatatg gatgtaacag ctggagataa
    25921 taaggtaaca tggaaagggt atttatcttt atttgtattg atagtattat tttcaggagt
    25981 gtttaaagat agtcaaggct tccttaaagc attagatttt gctaatctga caggttcatt
    26041 tggtactatt gcagatggtg tagactttat gggtaaagga ggaacgggag caaaagatgg
    26101 tttcttattt gctctgactt tgattccaac tgtctgtttt gctgtaggtc ttatagatgt
    26161 agttgaatct atgggaggaa tgaaagcggc atcaaagata tttaatccat tgcttagacc
    26221 tctgcttggt atacctggaa tagcaggaat agcatttgta tcttcattta ctagttcaga
    26281 tgtagcctca ataatgacga aagaattatt tgaaagtggg gaaataacag atgatgaaag
    26341 aactatattt gtagcatatc aatatgctgg ttcagctgtt atactgaaca caataaatac
    26401 tcaagctcca cttttaccaa tagcattatt ggcattaggt ccaataatcc ttatagagat
    26461 attctgtaaa atacttggtg ctaatctagt tagattaatc ataggtgtaa gaaataaaaa
    26521 gaataaggct aaggaggctg tgtagtatga gtcaacaaaa tactggaaat gcaattgtaa
    26581 atagtaaacc taagaaaact gctgttgaga tatttatggg gggagcaaaa aaaggttttt
    26641 acataggtgt tgaacagata ttaccagcca tgataatggg ttatgtaata gtgcagtttt
    26701 tacaattaac tggtttagtt gatattttag gaaatatttt tggaccagta atgggtattt
    26761 ttggactacc tggggaatct gttgtagttt tgatagcagc attctttgct aaggcagcag
    26821 gagcagctac agctgcaaac ttatttgcac aaggtctaat cactgcacca caagcaacca
    26881 tattaattat gccatgtatg ttaatgggta ctctagttgg tcattatgcc agaatagtgc
    26941 ttgtagcaaa tgccagtact aagtatagaa tgttactgtt ggcagttcct atatttgatg
    27001 caatagtggg gatgttaata gtaagagttt tactcactgt tatgggatta atgtaaataa
    27061 cataaaatta taacctaact ataaatgata tataagaatt aatatataca aggattaatg
    27121 agtagtaatt gatatatagt aataaactaa gatagtaatt aatgtgtata ttaattaaaa
    27181 aaagagagta tctcaaagtg aactttttag ttcataagat actctttttg tatgaaatca
    27241 agtatatttt cataatttca acaatgaaag agaggcttat ctctattttg agacagcctc
    27301 ttcttttaaa tttatatttc tagaatttat gttttttatt tatccaacat taacattagt
    27361 tattagaaat aattttaaga aaaatatact ttcatgttaa tatcagaata aatgtgtttt
    27421 taaaggatga tttgttttga attttcacga atatctactt ctatgacttt ttctattgta
    27481 tctcctctaa aacctaataa attacttgtc aagtttgcag tggaacaaga atgattaggt
    27541 ataattctta ttctatcacc aatttttata tcagtttcac catttacttt aatttttcca
    27601 acttcttctg aaagtgaatc aatagtaagt tctggatgtc cacataccct accataacca
    27661 acaatactac tatttccatg tgcaccttta tcaagtccaa ggcacttact tccacaatca
    27721 attaaatagt atccactgct attttttgag attacagtgc acacaacagt aagagcacac
    27781 atatcttcag tagcacaacc taaacctatc tgtatagcat catagtatac atagtttcca
    27841 ggtcttacag cagttatagt tttagaagca gcttcagatt caactgttgg agtactacca
    27901 gaagcgacaa tttctatatt aaatccatta tcagttagag ctttgtatgc tttctccata
    27961 gaagaatctt cttgaacaca aacatctgga acaccttctg gagaactaca accatacact
    28021 tgacctggat gcgaacttat accaacaatc ttgatgtttt ctagcttaga aatttcagta
    28081 gcaagttcaa ccactttttc tggttcaacc ccaaaacggt gtaagccaca atctacaata
    28141 ataagtagct tgcactctat ttttgattta gaaaaagctt cactataagc cttagcacat
    28201 tctatattat ctgtagcaca gattaaattt atttttgatg ccatagtcac aattctattt
    28261 atatttactt ctcccatgta aggataagcc aacataatat cttcaaaacc tgcttttatc
    28321 agagcttcac cttcatcaag tgttccaact agaaaaccac tagcacctgc atttttttga
    28381 agtctcgcta tgtaagtact tttatgtgtc ttaagcatag gccaaagttg tttattatta
    28441 tttgtacaaa tttgttgaat tttatctata ttcttttcta actggtctaa atctagcaaa
    28501 aaatttggag tagcgacttc tgaaattttc atgttattta ccacctttca acaaaagtaa
    28561 attaactata agtattataa ttattatatt agtaatatcg gctttataat attaatagct
    28621 tataattata ttatagaact agcgttaaca gagagcaata tttatttgta ataattagaa
    28681 ttttcaataa gttagtgtag ttttaaatta tttatataat atatttttaa ttttatgcaa
    28741 agtttattta aattagtttg aggatttatt aatagggtat tattgaatga gtaaaaaagt
    28801 gatgtttaca tagaataatc acactataaa ttaatttaga acctaaaaaa ttaattgagc
    28861 aaattggaaa agagaaggat aaaaaagata tttggatagt tggtggaggc gatatagtaa
    28921 aattatttat gaaagataac ttaattgatg attattatat atatatattg ccaataatat
    28981 tggggagagg gatttcacta tttaagtctg gtatagacaa gactaatttg aattttaaga
    29041 aagctagtaa tattggagaa cttgtaaaat tggaatacag taaaaaacaa aaataaatta
    29101 catgccaatt tgttacaatg ttatgaaacg aagcatttaa aagacttttg gctatatgaa
    29161 ttgacattac ttgtcaaata tgttaacata taagcgactt gtcggagggt gtattaaaaa
    29221 gaatatgctg gagaagagag tgcgttaact cttttctcct ttttttataa aattaagcat
    29281 ttataaattt agtattatta catgattaca ctatctcaaa aattaagaaa ggagaaaaat
    29341 atgaaattaa ttttaagtta tttaaagaat tataagttat taatagtatt aaacatactg
    29401 gctatattta gttttgcatt agtcgagttg gggattccaa ctataatagc taaaataatt
    29461 gacaatggta ttgcaaatca gaatatagct tacataaaac aaatgggaat agtgattgtt
    29521 attatttcta ttataggggt tgtaggtagt atattgttgg gttattgttc tgctaaggta
    29581 tcaacaagtg taaccagaga tataagaaat gacatatttg agaaatcaca agaattttca
    29641 catactgaat acaataaatt tggaatttct tcaatgatta caagaacaac gaatgatgca
    29701 tttcaaattc aacaatttgt taatatacta ctaaggactg ccttattaac tccagttatg
    29761 ttcattataa gtataataat gacaattaga accagtgtgg aactttctat agtattggct
    29821 atatcagtac cttttataat tattggagta gcaataatag caaaagtatc tcaggcaata
    29881 tcttcaaaac aacaaaaagg actagataaa ttaaacctta tatcgagaga aaatttaact
    29941 ggaataagag taattagagc ttttggaaat gatgattatg aaacagagcg atttgaaaaa
    30001 acaaatacat attatgctaa tgtttctaag aaactattta agcttatgtc aattactcaa
    30061 ccagcattct ttttactgtt aaatatagct gttttggctg tattttggat ttcaagtgag
    30121 aagataaata ttggagagct tcaagttgga cagttggttg catttttgga atatcttttc
    30181 catgccatgt tttcaattat gcttttttca atggtattta ttatgtatcc aagagcagag
    30241 gtatctgcaa atagaataaa agaactatta aatgaagaac cattgataaa aaatcctgaa
    30301 aatggaatta aggatactga aaataagggt atcatagaat ttgataatgt aacttttacc
    30361 tatccagatg gagaagcttc tgtacttaag gatatttcat ttactgcaaa aacaggtgaa
    30421 acagtcgctt ttataggaag tactggtagt gggaaaagta ctctaattaa cttgatacct
    30481 agattttatg atgtaacaga aggtagcatt aagataaatg gagtagatat aagagaatat
    30541 gatttaaaag ctttaagaaa aaagatagga ttcatacctc aaaaatcact gctttttact
    30601 ggtagcatag caaataatat tagatttggg aaacataagg caggagagtc agaattagaa
    30661 tattccgcaa aagttgcaca agcatatgag tttatatcaa aaaaacctag aaagtttgat
    30721 gaattgatta gtgaaggtgg agcaaatgta tcaggaggtc aaaaacaaag actttctatt
    30781 gcaagggcta ttataagaag acctgaaata tacatttttg atgacagttt ttctgcactt
    30841 gactttaaaa ctgatgcaat acttcgtgct aaattgaaga aggaaacaaa agatgcaatt
    30901 gtattgattg ttgcccagag aattagttct attattgatg ctgataagat tatagtactc
    30961 aatgaaggac aagttgtagg aatgggaact cataaagaat tattaaaaaa ctgtgaaata
    31021 tactatgaaa ttgcaacatc tcagttaaaa aaggaggaat tagaataatg aaaaagtcta
    31081 aaggttttaa gaaaacaatt ggtagacttc ttccatttgt aaagaaatat aaattttcct
    31141 ttattatagc tattatatgt ataatttcag cagctactat gaatgcactt gcacctaaaa
    31201 ctgaaggatt gataataaca caattgacta aagatgtaat tagtatcgca aaaggagtac
    31261 caggggcttc cgtaaatttt gattatgtaa caaaaatatt ggtgatttta gcatgtatat
    31321 attttgccaa tgcaattttt acgtatactt caagttttct acttacgaat gctattcaaa
    31381 acacaatgag agatttaaga aatgaagtcg aaaataaaat aagaagattg cctattagtt
    31441 attttgatag taatagtttt ggagatgtat taagtcgtat atcaaatgat gtagatacaa
    31501 tatcaaatgc attgcaacag agttttatgc aaattgtaaa ctcaatctta gtcataattt
    31561 tggctctttc aatgatgttt acaattaata tatatatggc tcttatagct ctttttataa
    31621 ttccaattag ttattttgta tctaaatttg tagtaaaaaa atctcaaagt agattttcat
    31681 tgcaacaaaa tgctcttgga aaattaaatg gaaaagtaca agaaatgtat actggattta
    31741 atgaaataaa actatatggt aaagaagaag attctataaa agaatttaaa aaagtaaatc
    31801 aagaactttg tgaaaatgga tttaaggcac aatttatatc aagtatgatg aatcctatgg
    31861 tttcattagt aacttacttt ggaattgcag ctgtggcagt tgtcggttct atatatgcag
    31921 taagtggagg aataacagta ggaaatttac aagcatttgt gcgttatata tggcagataa
    31981 atcagccact ttcacaaatg actcagttat ctacagtaat acaatcttct tttgcagcta
    32041 tagaacgtgt atttgaaatt ttagacgaag aagaggaaat acctgatgtt gaaaatccag
    32101 ttaagataga aaatgtaaaa ggaaatgtta catttgagca tgttaatttt ggatatggag
    32161 aaaattcaac tttaatagaa gatttaaatg cagaagtaaa aagtggtcag atggtagcta
    32221 ttgttggacc tactggagca ggtaaaacaa cattaataaa cttattgatg aggttttatg
    32281 atgtaaagaa aggtgctatt aaaattgatg gagtagatat aagagatatg aaacgtaaag
    32341 atttgcgttc aatgtttggt atggtgcttc aagatacatg gttatttaat ggaaccattt
    32401 ttgaaaatat agaatatggt agatttgggg ctactaaaga agaaattata caagcagcaa
    32461 aagtagcaaa tgttcatcac tttataacca ctcttccaga tggatacaat atgtttttaa
    32521 atgaagaagc atctaatata tctctagggg aaaaacagct tttaaccata gctagagctt
    32581 ttatatcaga cccttcaata ttgatacttg atgaagctac gagttctgtt gatactaggc
    32641 tggaacttat gcttcaaaaa gcaatgagaa atcttatgaa tggtagaact agttttgtta
    32701 tagcacatag actttctaca attcgcaatg ctgacttgat tttagttatg aataatggaa
    32761 gtattataga gcaggggaat catgatgaat taatggaaaa gggtggattt tatgagaagc
    32821 tttataatag ccaatttgca gacaaagaat cagaatagat aacataaact tttgtataaa
    32881 attttgtatc aaattcaaat attaatcata taattaaaaa gagtatcagt aagttgtttt
    32941 tttatagatt tactgatact ctttgatttt aagactaaag gtatttatga ttggtactta
    33001 taattcacaa ctagtcttgt tacatctgat aaccagaatt acagtacttt tcttttttac
    33061 ctttttgttc tctaacatat aacaattcgc ttaacttatc aatgtaataa ccatcatcac
    33121 ttatgcgaat taaactagtc agataatatc catctttgct tctaggaatc tttttattta
    33181 ttgctaaatc aatagctgtc tttgctgctt caaaatgctt taaatgtgta tgaccttctt
    33241 caaaactctt tctagtatta taaactacat aacctttttt aacttgaaaa actataaatt
    33301 ctttcttttc atatatttta ttaaacattc aatcagccct tctcaagata gttttatagc
    33361 ataacattag aagcttctaa aaaattttac aaagaacata aatattttat aaattataaa
    33421 tctaaaacta taatttataa agataacttt ctgattattt atatgataat tcatatagat
    33481 taaaagtaaa ttatctttag gttaaacaaa agtaaaataa aagactagtt ataatattta
    33541 tatgaaaaag tacaaaatat agtatatgaa tatagaaaat ttaaattatt tatttacagt
    33601 ttttatttcc ataagtatat ttaccttcag ataccttgtc atcatggaaa tatattcttt
    33661 cacaactttt atctccccat agaatgtttt ttgttatttt atgggaagta tctcctgtaa
    33721 atacttcagc tacagtagta tctgtaacat cacagtaaag agaagcaaat tttttaaacc
    33781 aaggattttc ctcaaatctt aaaagccagg aagctccata ggggcaatgt aactcttcaa
    33841 attcaggaac ccatcctaga aatggaacat cagttgtgct aataatattg tctgcgatta
    33901 attcatctcc attttcatga gctctctctc tcatagcaat agctctttct tcagaccttt
    33961 caaataaaac ttttcttaat atttcgctag ttttatcttc accaaactct tcaaataaca
    34021 ctttggaaaa ataaaaatat aaatcaccaa aatgtttgca tgccatacga acttcttcaa
    34081 tagcataatc tttgtcaata gtttcattag ttacaacatc ttcgttcaaa aaaatcactc
    34141 cttagaataa gtattagtta caatataatt atagaatatt ttttataaat taggaaatta
    34201 atttgagata gatatatttt taataaatga aggtataatg ctaaaataac ttattgttac
    34261 aaaaatcttc taaattaatg tatttaggag tttccatatg aatgagagta gttctgtaaa
    34321 tatcttcaat acatccattt gcaatattat taaaaatatc tgtgtgctct tttaatgttg
    34381 tttcaagcct tccttcatgt gacaatgaat cgagagctaa tttttttatt ctgtacatat
    34441 aattgttaaa cattttgtca aattcagtat tttgagcata tgaaactata gttgtgtgaa
    34501 ataatgtatc atattctgca aatgagttta aatttttatc acctaataaa atatcttttt
    34561 gtttatctaa aagatgtttt aatttactta tagtttctac tgctctagct tctttgtatt
    34621 gacttgtaat taaaaaagta caaaatcctt ctattgcaga gcgtatttgg aatatctcta
    34681 caatttcatt tgctgtaatt tgatggattc taaatccttt gcttgggatt atatctataa
    34741 atccatcttg actaagtctt tgaagagcat ctcttatagg tgttctagaa atacctattt
    34801 cactagcaag ttttgtttca gaatatattt cattttctat catttttcca gatagtatca
    34861 attcttttaa gtagtcatat gcttgttctt gtaatctttt aaatgtagcc atacttaata
    34921 atacccccct aaacaatata aaaatacaaa aacttatata attttaagca tacaacatag
    34981 tgaaaataag gtcaatcttt tgcaatttaa attgcagata agattaaaaa atataaaaaa
    35041 ttattgaagt gtgaagcatg attaacatta aaggcagatt aattaaaact aattgaaatt
    35101 agttaaaata caaaactgta aaagtagtat attatatttg aaaacaatag tatgtattaa
    35161 aacttatata ggatgactaa atataataaa tgactttaaa aattactatt tattgttaaa
    35221 ataaatactt ttatatttta tattgaccgg tatactggta tgtagtatac tctaaaacat
    35281 aaaaaacgtt ttcaaaaatg tgaagatatg gagggttata aaatgaaatt gggatttatt
    35341 ggattaggaa taatgggaaa gccaatggca aaaaatttat taaaagatgg atgtaatctt
    35401 ttggtgtatg acattaataa atctgctgtg gatgaactta tatcatgtgg agcaaaatac
    35461 gcaagtgttt tagaaatggg tcaagaatgt gatattgtat ttacaatcct tccaaatgga
    35521 actattgtgc aggatatatt gtttgggatt gatggattgg caaaaacttt aaaagaagga
    35581 agtatagtag tcgatatgag ttcagttact cctacagaat caatattgtg tgcaaataaa
    35641 ttaaaagata tgggcttaga atttatagac tcaccagtaa gtggagggga gccaaaagcg
    35701 attgatggta cacttgcttt tatggctggt ggtaaggaag aaatttataa gaaagtagag
    35761 ccatttttta atataatggg aagctcatct attttaattg gagataatgg tagtggaagt
    35821 gttacaaaac ttacaaacca agtaatagtt aatttgacga tagcagcagt ttctgaggca
    35881 tttgtacttg cagcaaaagc aggtgcagac ccagaaaaag tatataaggc aataagagga
    35941 ggcctagctg gtagtacaat attggatgcg aagataccaa tgattatgaa tcgtgatttt
    36001 aaaccaggtg gaaaaatatc tattaatttg aaagatatta agaatgtaat gcaaacagca
    36061 cacaatttag atgtaccgct acctatgaca agtcaattat tagaaattat gcagacatta
    36121 aaagtacatg gacatttgga agatgaccat agtggaatag cacagtattt tgaaaagttg
    36181 gcaggtgttg aaataaaaaa acacgataat taatatttaa atatatcaat ataattaaat
    36241 acatattatt aggattagat tatataaata cagcgaggtt aagttatcat agtaaaagaa
    36301 aaataaaatt gataaataat aaagtagaat gataaagggg taaagattat gattacagga
    36361 tatggacttt tgatagcatt tgttatatct ataggaattt tacttgtatc gattattaaa
    36421 tttaaagtaa atccgttttt agcattactg ataacatcta taattacagg ctttatggtt
    36481 agaatgccta taaatgaaat atcaaccaca atatcgactg gatttggaaa tacattaggt
    36541 agtataggta ttgtaattgg acttggaata atatttggaa atattctttc agaatcaaga
    36601 gcaacagaat ctattgcaaa ggggttgtta gctaagactg gagaaaaaaa cagtgcttta
    36661 gcagtaacta cagcaggttt tttaatttca attccagttt ttatggatgc agcttttgtt
    36721 ataatgatgc ctataattaa gtatgtttcg agagtaacta agaaatctct aatggttttt
    36781 gtatgtgcat taggagttgg gactatagta ggtcatgcac ttgtaatacc tacaccagga
    36841 cctttagcag ttgcagcaaa tgtaaatgca aatgtaggta gttttatact ttattctata
    36901 attgttgctt ttccagcagc tcttataggt ggatggattt atggaaaacg ttttgaaaaa
    36961 tatccagctt atgctattga tgagaatgat agagaaaaaa atttagagca gggaaaagat
    37021 agcataaaaa ttgaagatga tgattcttct aaagtaccag gttttggaat ttctatgttt
    37081 tctttattgt tcccaatact tcttatactt atatcaaatg tatttagtat gttcttagaa
    37141 aaaggttcta caatgagtgg agtacttgca tttataggag ataaaaacat agcaatactt
    37201 cttggaatat tggtggcaat aggattttta aagaaataca taaataaacc tatgggagat
    37261 gtagttattg aagctgctga ttcagcaggg ctaatattat tgataacagg ttcaggtggt
    37321 gcgtttggca gtgttataaa tgcaagtggt ataggtaact tcttagttga tactatgtct
    37381 ggtcttagta tatcagttgt agtgcttgga ttcttattaa gtgccttgct tagaatttct
    37441 caaggttctg ctactgtagc cttagtaaca acatcatcaa ttttaggacc tacaattttg
    37501 gcaactggaa tgtcaccagt tttagtaggg cttgctatat gtgctggagg agttggtttc
    37561 tcccttccaa atgattctgg attctgggta ctttcaagat ttagtggatt atcagttaaa
    37621 gatactttaa actcttggac aattggagga accattgctg gagttgtagc atttataatg
    37681 gttttattgc ttagtgttat aaatggaatt ataccacttc caggtctata aataacaaac
    37741 tattgtttat atcatataaa ttacatttag actatacaaa ttacataaag gggcgtttta
    37801 aatgagagaa gtaaaaccaa ttagcataga tatacttaat acttttaaac aagtagatga
    37861 ggacagatta aataaacttc ttgcagatga gcttaagcat ttagatagaa aaattgttgt
    37921 attagatgat gacccaacag gtgtacaaac agttcatgat atttctgttt atactgattg
    37981 ggataaggat agtatggaac aaggttttaa tgagaaaaat agtatgtttt ttatacttac
    38041 caattcaagg ggatttactg ttgctcaaac tacaaaagca cataaagaaa tttcaaagaa
    38101 tattgtggat gtatcaaaga aagttaataa ggattttata atcataagtc gtagtgattc
    38161 tactatgaga ggacattatc ctcttgaaac taatttatta aaaagcgaag tagagagatt
    38221 atcggggaag ttatttcagg gtgaaataat aatgccattt tttaaagaag gtggtaggtt
    38281 tactatagat aatgtacatt atgttaaaga aggagaaata cttgtaccag caggaatgac
    38341 tgaatttgca aaagataaat cttttggata taaatcatct gatataggtg agtggtgtga
    38401 agaaaagaca aaaggaaagt acaaatctag tgatatgata tatatttcgt caaaagaact
    38461 tagagagcta aatattgaag ctataacaga aaaacttaaa aaagctgaag gattcaataa
    38521 aattattgta aatgcaaccg actatgtaga tgtaaaggta tttacaattg cgtttatacg
    38581 agcagtaaat agtggtaagg aatttatgtt tagaagcgct gctgccataa caaaagtact
    38641 tggcggagtg agtgataagg aactgcttac taaggatgaa ttagtatcaa aaggtaatac
    38701 caatggagga attatacttg ttggttcaca tgtgaataag actacccaac agttagaaga
    38761 acttaaaaat tgtaaatatc caatagaatt tatagaattt aatcaacatt tagttcttca
    38821 agaaaatggt ctaaaaaatg aggtaaaaag agttataaaa gttgtagagg aaaaaataag
    38881 caggggtaaa actgttgctg tttatactag aagagagcgt tttgacttgg atacaaatga
    38941 taaagataaa cagcttatga tttctgtaga aatatcagat gcagttacca gtataattgg
    39001 tatgcttaat gtaaggccaa attttattat agctaagggt ggaattactt ctagtgatgt
    39061 tggtactaaa gcactaagag taaaaaaagc tacagtaatg ggacagataa aacctggtat
    39121 accagtatgg atgacaggca aagaaagcaa atttcctaat atgccatata taattttccc
    39181 tggaaatgtg ggagagatta gcacacttag agaatcagtt gagatattga tggggtagta
    39241 tattagtgta ttgaagttta aacgcttaaa tttactgtgt taaaagtaaa ataaactaaa
    39301 attataaatt aagattaaaa ataatagtat attaattagg gtttagagta ttttacaaaa
    39361 aatattctaa accttaatct tatgtattag tatttttatt atttaactta tgtgtttatt
    39421 ttattattta tcttttttaa ttgatttaat attttctttg attttattta aaatatctgt
    39481 atgcttatta gagcttatgt tggggaatgc tttgattata cgtctatgaa gtaatttgtg
    39541 gttagacagc aaagtattaa gtttattttt tagctcatca atacgatttt tagcatagcg
    39601 atagttttct ttttccttaa gtatttcaaa tctatcttcc aaagtatcca gtctattttc
    39661 aactaaagat tcaagtttgt tttctatagt ttcttgtgta ataagtttgt agtattcttt
    39721 cttatctttt aattccttaa ttataagatt gatttgtttt aacttaccat ttaattgtaa
    39781 aattgtatgg actgtgataa ctaaatctaa aacaaaataa atttctatag atatagcaaa
    39841 tataaatagc acatttttgg agatagagtt aataaagtca accacaatag gatgtactat
    39901 aagcattaca atcaatgata atacaccaaa cataagtgag ttttccagac aaactcttcc
    39961 atgaatatta aatttatgtt tagaataatc ccaccaagtc atattaaata ttttttctaa
    40021 aataaagctc gtacaatact ccattatgct agttataatt atactaaaca aaaataacaa
    40081 aggaatattg tgtacaaaag gagtcaaggt agcaactatt gctaatgctc caaatccata
    40141 tatagggcaa aatggaccat ttaaaaaacc tctatttaca aattgttttt gtaaaactga
    40201 acaatatgta gtttcacaac accatcctat aaagctataa attacaaaat aaagaaattg
    40261 aatataaaat gtactcataa gcacctcatt tctagttagt ataacactat atactcgata
    40321 ttttattttt ttgattaatt tactaaattc aatttacata ttgattatac caatttatag
    40381 aaatttatca aatttaatta cagttagaac attataaaca tggttataat aatgaaattt
    40441 tatttaaaat aaataagggt gtcaagtata atcaaactaa tagttgtaga tactctacac
    40501 tatgttagtt taattacatt tgacaccctt atatttatac tatgactatt tacattcgaa
    40561 actagagcaa catgtttcaa tataaaggtt tactctatca gtttcaggag caaccaatat
    40621 attatcaagt gtacataagc taccatcttt gttgtattta caatttttta cagtacaaac
    40681 taattcctca caatttctat tattaacgtt gctagataaa ttactataaa tagattcatc
    40741 taaaaatgaa ctacaacaag tatgtctgtc attgtgagct ttttcaccat ttataaaaat
    40801 tttatctgca taacatatat ggctgttgtt atgtgaacag ttaattacat tacagtttat
    40861 tctttccaaa gttattacct cctaaacgat tatttattat aaattatgtc catataatta
    40921 caagaatata accattaaga gaaaactacc ttttagaaaa tatctattct tagagtaatt
    40981 tgaaatataa atatattttc ttctaaaatt tacctaaatt gtataaaaac ttacagcttg
    41041 gagaaaataa tagaaaaagg aggcgtaatc aatgtttgaa aagaagaaaa aagaattatt
    41101 tccttggaaa atatctgcct taatactggt tggagtattt gtattaagta gcggagttta
    41161 tatagggaca agattaaaac acaatggagt tcaaactggt gaagttgtaa gtactagtgc
    41221 gaatatgaat gaaaagtcaa aagaagcttt tggattaaat aaaaattgtg aagtttggct
    41281 tcaaagtgaa ggcgaaaatg aaactaacta taagagaaca cttacaatgg caggaatagt
    41341 tccagagtca ttattagata agacgaagtc agaaatagta tcatatttta aaaaagaata
    41401 tccaactaaa aaaataaaga gtatggataa aaatgaaatc atattggtag aatctaaata
    41461 tagtgataat aaagatgtac aagcaatgga tgttactata aaaggtaaat atactattga
    41521 aaatgataat ggaaatatag cactatataa atatgatgat agcggaagta aaacattagt
    41581 agaaaaaaca aaaataagag tagattcact tcctaaaaca gttcaagatg aaatcaaaaa
    41641 aggtgtagtt atggatactg aagaagaggc ctattcaaga ttagaagact ttgcaagtta
    41701 atagtaaatt aatattattt taagttaaat actaagtaag ttaaatacta agtaaattaa
    41761 taataaataa tttaatatta aatagattag tattaaaatt gtagtcacat ttaattccta
    41821 taaaaataca ataatttatt tgtaataaat ataaaagtta tattgaggta aaatcttgct
    41881 ttgatataac ttttttattt gattttatat tttacataga gcattttatg atttgttaat
    41941 attatttatg atataatgat ttagaacata agtttttatg agaaatacat tttggtattt
    42001 cttttatttt tagggggaat tttaaaaaat gataatattg gggattgacc caggtatagc
    42061 catagttgga tatggtataa ttgaatacaa aaatagcaag tttaaagtaa tcgattatgg
    42121 agcagttaca acacctgccc atatgaatat atcgagaaga ttggaacttg tgtataaagg
    42181 aattgataca atagtaaaga attacaatat agatgaagtt ggaatggaag aattattctt
    42241 taacaagaat gtaaaaacag ctataacagt tgcacaagct agaggtgtta ctatgcttgc
    42301 atgtgctcat aatgggaagc ctgtatatga atacactcca cttcaagtaa aacaaggtgt
    42361 agttggatat gggagagcag ataaggcaca agttcaacag atggtaactt catttttaag
    42421 tctaaaaaaa gttccaaaac cagatgatgt tgcagatgct ttagctgtgg ctatttgcca
    42481 tgctcattca aacaaacttg aaaaaactct aaagaatata ggtggtaagt atgtatagtt
    42541 atataaaagg tacagtagaa gaaatttata tagacagtat agttgttgaa aataatggga
    42601 taggatataa aataaatgta tcatccaata caataatgaa tttacaagtg ggagaagcca
    42661 caaaaatata tactaaatta attgtaagag aagatgatat gagtctttgt ggttttgtaa
    42721 gtagggaaga acttaagatg tttgaattac taacatctgt atctaaaata ggacctaaag
    42781 tggcgctttc aatactatca tttgcatcac cagcacagtt aggagcatat attttaagtg
    42841 aagacattgg aaaattatcc aaagctcctg gtgttggtaa aaagacagca gaaagaatcg
    42901 tcttagagct taaggataag gtagacaaaa ataacataga gtttgaacca acgttattat
    42961 cacaaaaacc taccttgata tcacaagatg agtctgtaga tgcacttgta gctttaggct
    43021 atactttgtc ggaatcaaaa gaggcagttc aaaaatgtaa aaaagatggt atgaatacag
    43081 aagctattat aaagaaagca cttacatata taatgagtaa atccttgaaa tagtatttgg
    43141 attttataat atttggattt taaaacaata tttaaggagt ttatgtaaat ttgaaaatat
    43201 ataaagtaga ttttcaaaag tatgagagga ggggtataaa tgcaaggttt tgaagatgaa
    43261 aataggataa taacttctac aatgaagatg gaagatatag atatagaaaa tagtttaaga
    43321 ccaaaaactt tagaagatta tttgggtcaa gaaaaatcca aagaacaact tagtatattt
    43381 atagaagcag ctaaatcgag aaatgagcag ttagaccatg tgcttttata tggaccacca
    43441 ggtcttggaa aaactacact agcaagtata atagcaaatg agatgggggt aaatttaaga
    43501 attacgtcag gacccgcaat agaaagagct ggagatttgg cagccatact tacgaattta
    43561 aatgaaaatg atgttttatt tatagatgag attcatagaa tcaatagaag tgttgaagaa
    43621 gttttatatc cagcaatgga ggatttttgc ctagatataa taatagggaa agggccatct
    43681 gctagaagca taagacttga ccttcctaaa tttacactta ttggagctac tacaagagct
    43741 ggtatgctta caaatccact tagagataga tttggtgtta tttgtaaatt ggactattat
    43801 acagttgatg aactttcaaa aatagtactt aggtcttcaa gcatcttaga tgcagagata
    43861 cagtctaatg gagcattaga acttgcaaaa cgttcaagag ggactccaag gatagcaaat
    43921 agattactaa aaagagttag agattttgca caagtcagag ctgatggaaa aataactgat
    43981 aaggtggcaa aagatgctct ggaactttta ggagtcgata gtttgggtct cgattttgta
    44041 gatgagaagc ttcttatgac tataatagaa aaatttagag gaggaccagt gggtttagat
    44101 acattggcag cttctatcgg agaagataga aatacaatag aagatgtata tgagccatat
    44161 ttgcttcaat taggatttat aaatagaggt cctagaggaa gagtagctat gccattagca
    44221 tatgaacact taaaaattcc atatcctaat gaaaaataaa aatagattat acgagtattt
    44281 ataaaataaa agagtcatta aattaaaata tttctaaaat ggctaaaaat tcaaacatat
    44341 ccacaaaatg gtaattatat ctgtagatac tgtggataaa cacgataaaa attgtgtgta
    44401 ttgtatctat atattgtgga taagacatgt atatcgtgga aaaatatcta tatattgtgg
    44461 atatggtgtc tgttaaaaat agcaatttct tgatagatta tggtaatatt gtggaaaata
    44521 agttgttttt ttgatattat tgtagctgga gaaattttaa gagaggaagt ttaacattga
    44581 aaacaagtga ttttaaattt gacttaccac aggaacttat agctcaagtt cctatagaag
    44641 atagagctag ctcaagattg atggtattag ataaagagac aggtaatatt gaacataaag
    44701 tatttagaga tataatagaa tatttaaatc caggagattg cttagtatta aataatacta
    44761 gagttatacc agctagatta ataggagaga agcttgaaac tggaggtaaa atagagtttt
    44821 tattattaaa aagaacagag gaagatactt ggcaggcttt agtaaaacca ggaaaaagag
    44881 caaaagtagg gactaaattt tcttttggaa atggaaagct aattggagaa gttgtagatt
    44941 tatcagatga aggttcaaga attataaaat tccattatga tggaattttt gaagaaatat
    45001 tggatgaact tggaaatatg ccactacctc catatatcac tgctagacta gatgaaaaag
    45061 aaagatacca gactgtttat tcaaagcata atggttcagc agcagcacct acagcaggat
    45121 tacattttac agaagaattg ttaaataaaa taaaagaaaa aggtgtagat atagcctttg
    45181 taactctaca tgttggctta ggaactttta gaccagtaaa agtagaggat gttttaaatc
    45241 acaagatgca ttcagaatat tatatggtta gccaagaagc agctgacaaa ataaatagag
    45301 caaaggaaaa tggaaaaaat gtaatatgtg ttggtactac cagttgtaga actatagaat
    45361 cagcttgtaa tgagtatgga aagatgaaag aaactagtgg atggacagaa atatttatat
    45421 atccaggtta taaatttaaa gttttagata aacttattac taattttcac ttaccagagt
    45481 ctacactaat aatgttagta agtgctattt gtggaaagga taatgtttta aatgcatata
    45541 atgaggcagt aaaagaaaga tatagattct tcagttttgg agatgctatg attataaagt
    45601 agggaggtaa tggatgcata gtttacaaaa acaaaaaaag aataacccta tattaaagat
    45661 tgcttttata tttgaacgtg ttttagcagt agtagttcta atagcagtat ttttaggaac
    45721 tatagatgtt ctaagactta tgtggggagc atatatagtt gattttcaaa atccagtaca
    45781 atacagtcag cttaatgatt ttttagcaca aatattactt ttagtaatag gtgttgaact
    45841 tgtagtaatg ctatctcttc atataccagg agcatttatt gaggcattac tttacgcaat
    45901 tgctagaaaa atgttgctac tgcctaaaaa tgaaggtatg atagatgttt taataggagt
    45961 tatagctata gcaggactat ttgctataaa aaagttttta gtaacaaaag acaagagtgc
    46021 tcttaatata atgagtattc atgatgaaga agcaattaag gaacaacaga acaaagaaga
    46081 cgaagataaa tctatttaga caataaatta tatgaatagc ttattacaaa tatatcttaa
    46141 gaaataatga gaaataaata tgattaagga gaactttatg tacgcagtaa gatacgaatt
    46201 gataaagact tgtaagcaga gtggtgcaag gttaggaaga ttacacactc cacatgggat
    46261 tattgaaaca ccaatattca tgccagttgg aactcaagca actgtaaaat ctatgacacc
    46321 agaagaatta aaagagattg gttcacaaat aatacttagt aacacatacc atttatatat
    46381 gagaccaggt catgaactta taaaaagagc tggtggtctt cataagttta tgaattggga
    46441 taaaccaata cttacagata gtggagggtt ccaggtattt agtctagggc ctttaagaaa
    46501 gataaaagaa gaaggtgtag aatttaggtc acacttagat ggttcaaaac attttctaac
    46561 tccagaaaaa gctatggaaa tacaaaatgc attgggttca gacataatga tggcatttga
    46621 tgagtgtgca ccatacccat cagatagaga atatgtaaaa aattctttag aaagaacaac
    46681 aagatggtta aaaagatgta aagatgccca taataatacc gacaagcaag ctttatttgg
    46741 tataatacaa ggtgggatgt ataaagactt aagggaacaa tcagcgaaag aaataactaa
    46801 tattgattta ccaggatatg ctattggtgg acttagtgtt ggagaaccaa aaccacttat
    46861 gtatgacgtg ttagagcata caactccact tatgccaaag gataaaccaa gatacctaat
    46921 gggagttggt agtccagatg acttagtaga aggtgttata agaggagtag acatgtttga
    46981 ttgtgttcta cctactcgta tcgctagaaa tggaactgca atgactagcc aaggtaaagt
    47041 agtagttaga aatgcaactt atgctgaaga ctttactcca cttgaccctg aatgtgattg
    47101 ttatgcttgt aaaaactatt caagagctta tataagacac cttataaaag caaatgaaat
    47161 actgggtgca agattaataa ctactcataa tcttcacttt ttattaaatt taatgaaaca
    47221 aataagacaa gcgataatgg aagatagatt acttgatttt agaaatgaat tttttgcaaa
    47281 atatggatat gaaatatagg ttttgcacta ttaattataa tcattttaat atataatatt
    47341 caatagtact caaagataga gaaagtaaat tgttatataa acatttatta tgatttacaa
    47401 aagagtataa tttacaaagg agtgaaaaat taatgccaca gcaacaaata attatgagta
    47461 taggtctatg ggtagtagta atcgcaatct tttatttcct aatgattaga cctcaaaaga
    47521 aaaaagacaa acaattaaaa gaaatgagaa gcagcctaag tgtaggagac aaggtcatta
    47581 caataggtgg aatagtagct aatgtagcta aagttgaaga tgatgttgta atattagaat
    47641 taggaccaaa tagaactaaa gttccatttg aaaaatgggc tataggaact gttaaatcta
    47701 aaaaagaaga aatagaagaa gactaaatta gtaatttaaa agccttttct cgaatatata
    47761 ttaatttgag aggaggtttt tttatgggaa aatctaatta tatttttaaa ggtctaggat
    47821 atgcatatat aataactttg gctgttttat tagtgtataa cttatttttg acatttacag
    47881 atattggtgg agataatata actatggtct catcatttat aactactatt tctgcagcta
    47941 taggagggtt ttacacttca aaacacatga aagaaaaagg acttatgtat gggcttttag
    48001 taggactttt gtacatagta tgtatttttt tgactgtgtt tttagcacaa gaaaagtttg
    48061 tatttgaaat agggatgatt tataagttat tgctaatatc agcagcagga ggcattggag
    48121 gcgtattggg tgtcaacttt aaatagagtt tatattaaag tagttttatg atataatcaa
    48181 taggaaacaa ttagaaatgg aggcgttgaa aatggaaaat aaacatgtaa aaactttatc
    48241 tcaagctact ttaaagcaaa gtgctgcaaa aggtggatgt ggagagtgtc aaacttcttg
    48301 tcaatcagct tgtaaaactt cttgtacagt tgcaaatcaa gagtgtgaaa gatagaaaat
    48361 tattgattta gttgtttgta agagggtatc tcaaagtgat tcttttatca ttatgaggta
    48421 tcctctttta ttttcaatta ttatataaaa atatatattc tatttatgta gaagtaaatt
    48481 tgatttctta tcgtttaatt atgcaaaaat atctaatcat gtaagagcat ttattttaaa
    48541 gtagctactc ttatatttta ttttttatca attacatgta ttagaataat ttttaatttt
    48601 aaactctaat ttatgatgat ttttataata tgttatatat tttaatatat ggagatagat
    48661 attaatttag tgatatatat ttaagtaata agagtaaagc aaaaattagt gcatagtagt
    48721 atataaaaat ggagtttgaa tacttttgtt agtatatgat tgtttagtag aaaatcacta
    48781 taaaatagga tttctatctt tgagcataat tatagagagc ctaagtaggg ggaagggttt
    48841 caagaagata ttattagtgt ttgtgttagt aaattatgta aacacataaa atatattgaa
    48901 aaataatatt atatataata ttatttatgt gtgggaaata cgaatataaa aaataaaaaa
    48961 taatattcgg aggacataaa tatgttaagc aacaaaaaga gaagtatggc aatagtaatg
    49021 gcaggtgcta cagttatgag tgcagcagca ccaatattcg cagacaatac cgtgacagaa
    49081 aatgttgata aaaattacac agtaagtgcg aaagattctg ctaaactaat cgaagaggtt
    49141 agaaaagcat tagaagttaa gtttgaagat acaaaagcag gagcaaatgt aaatgataga
    49201 gtttacgata taaaagtaga caatgtaaac ttaactaatg caactcaatt acaaaataaa
    49261 ataaactctt taacagaagg gcaaagttta aaagttacta ttcaagataa agggcatcaa
    49321 gtgttaggtg gaaaagtagt tgactataaa attgaaaact acaaaactgc tcaagaaata
    49381 gtagatgcag ttaatgctta caatgcaact ttagcagaag attctgataa caagttaaca
    49441 gcaactataa aatctacaaa tacagttgaa gtaaaaagag caaaagattc agcaaatgtt
    49501 attacattaa atgtaggaga ccaacattta gatttctcaa aagtgataac atcagaagaa
    49561 ggtacttttg aaggttatga aaagagttat agtgacatag attcaaaaga attacatacg
    49621 ataacagtta aaaacgcaga tttacaagac atatcagcag aagaattatt tgatggaatt
    49681 agattaacta cattaggaag agaaatagtt aataaagtta aaaatggata tgctttaaca
    49741 tttgaaaatg aagcaatcct tactcaagaa caagaagata gtgatgataa agataaacca
    49801 gaaaaatcaa gctttgatat agttttaagc aaggcaaatg aaaagccaga aacaataagt
    49861 gtttcaagta aaaaccataa gttagttaga gacttacaca aagtattaac tgatgtaaaa
    49921 gatggaaaag aattaaaagt agaagtttta tctggtgatt caagatttac aacagcagta
    49981 gaagttagta aagagagatt taaagatgga gaagcagaag ctataatttt agttggagaa
    50041 gatgctatag ttgatggatt agcatcagca ccacttgcct ctcaaaaaaa tgcaccaata
    50101 ttattatcta aaaaagattc actaccatca gaaatagaag ctgaaatatt aagagtactt
    50161 ggaagtaatc tatcttctaa gaaaatatat atagtaggtg gagaatctaa agtatcaaaa
    50221 gaaactgaag aaaaactttc taaattaggt gtaagtaaag ttgagagagt ttctggagaa
    50281 gatagatttg aaacttcttt agaaatagca aaacaattaa aagatacatt taagactgct
    50341 tttgtagtag gtggaaatgg agaagctgat gctatgagta tatcagctag agctgctcaa
    50401 tttggtgctc caataatagt tacaggtaac gaattagatg caaatgctga aaaattatta
    50461 aaaggaaaag aattagaaat agtgggtgga gaaaattctg tatcaaaaga agttgaagac
    50521 aaattagttg atatagattt aaataataaa gttgaaagat tagctggaga aaatagaaaa
    50581 gatactaatg ctaaagtaat caataaatac tatgcaggtg caactaaagc atatgtagca
    50641 aaagatggtt atgtaggtgg aaatggacaa ttagttgatg cacttacagc agcaccactt
    50701 gcagctagtt caaaggctcc aatagtatta actacagaag aactttctaa atcacaagaa
    50761 gaagtagttg agttaagact taagaatgct actaagttag tacaaatagg tgaaggaata
    50821 gctaaaaacg ctattgaaaa aatagcagaa aaaataaact tatttactaa gaactaataa
    50881 gatataggaa ttaatattaa aagtttattt agataatata tgattataca atgcgttaat
    50941 atgtaagaca tagtgtagat attataaaat atacaaataa caagataaaa taataaaaat
    51001 aaggtgtctc atttagaatt agattgagat accttatttt attttttgat tataatgttg
    51061 agaaattcat attgcaaaaa ttattataaa aagatacttc ttataatgat taaacatatt
    51121 actaacataa attattttga acttataacg taattaaata aaataaatta taatgttttg
    51181 aatttataga gaataaaaac tttaggtata ttgtttgagt tgtatggata actatggtat
    51241 catatataaa atatggtaac aaaattgtaa cttttgatta aaaataagta tgagtactaa
    51301 taaaaaatat gaaaagtaca ttgggggtag aaaataatat gaagaatagt aaaaagatat
    51361 tagctatagg acttacacta tttttagtaa tggtaaatac tcctatggta aatgcgttga
    51421 catcagttga gcaaataaaa gggaatgaca gatatgagac agcagcaaaa atagcagata
    51481 agcaaaacta caatacagca atactaatca actcagataa tagcttagca gatggtctaa
    51541 gtgcaagtgg tttagctgga gccttaaatg cgcctatttt gatgacaaaa caaaaccaga
    51601 ttccaaacac aactatggaa agattaaaca aagcaaagac tgtgtatata ataggttcag
    51661 aatcaacaat aagtaaaaat gttgagaatc agttactatc caaaaagaag gttgtacaaa
    51721 gaatatttgg tgaaaataga tttgatacaa gtataaaaat agctgaaaaa atcaaagaaa
    51781 ttaagccaat agataaagta attatagcca atggatttac aggagaagca gatgcgataa
    51841 gtgcatcacc agtagctgct agagatggag tacctataat acttacagat ggaaatagtg
    51901 tgggatttga cacgacaggc ttaaagagtt atgcgcttgg ttctagtgaa ataataagcg
    51961 acgaattagt taagagcaca aattctatta gattgggtgg cacagataga tttgaaacta
    52021 ataagatagt tatacaagag ttttataaaa atagtaaaga attttatcta agtaaaggct
    52081 tacaattaac agacgctttg gctgcctcta caatagcaaa aaatgctcct gtagttttag
    52141 ttgaaaatgg cagtaacaag agtattttaa gtggtgcaga caaattgact gtactaggag
    52201 gcataaatca gaatgttatc aagcaatgta taaatcaagc ttcaccaaat caacaaggtt
    52261 tatattacaa tccaaatgat agagcattta aagagagaat aaagggtaaa gtatatgctc
    52321 ttacaaagca gtatagaaaa gagaatggag taagagcgtt atctgtagca agcagattag
    52381 agggtctagc aaatgattgg tctaatttaa tggcaaataa gaagacttta tctcatacga
    52441 taaatggaaa aaattcatat tctacttttt tgaaatactt agattggagt gagattaaac
    52501 ctggatatat agcagttcaa ggtgaaaata taattaaata taaaattcca gataaacctg
    52561 tatatacaaa tagagatgca gatgatatag gaaactttat ttttaatgag tggaagacaa
    52621 atccagaaga aggaactaat atgttgcata aagggtatga aataatggga tttggtatag
    52681 ctataacagg agataagaat ctatatgcta cacatgaatt ttatggaaga tataaagaat
    52741 aagaaaatat acacaaaatt atgcttgtaa ggaagctata taaataatta aattataatg
    52801 gaaaatagca tttatattaa taaattaata taaatgttat ttttttataa tttaatctaa
    52861 aaaaattata ttaaaaagtt taaatatagt ataaaatggg taagaaagta gtgaaaatta
    52921 aatggcaaaa ttagggaaat ctaatgacgc aaaactatag ggattaaagc ttttaaagcc
    52981 atatcagcca gttgctaaaa agagtaaagt ctttttattt tataattaag attctctttg
    53041 agtgtctttt tttattgtct gaaacttata gtatttaaat tcatgaaaaa ttagatattt
    53101 attaagggag gattgttatt tcatgaaaaa ggcaatatct tgtgtactag cagtatctat
    53161 gtgtagtgca ccactaaacg tttttgcaga acctatatta gaggggaagc taagggcagt
    53221 tgaaaaatca gttacagaaa agttaagggg gagtcttgaa gtagatttaa atttttcact
    53281 gccaataaaa aatagcgagt cagaaagtat gactaatatg cagttacgat taaaagatga
    53341 tagtaacaat agtggaataa taaagcttgg agaaaaagat tcaggaacag taaatgttgg
    53401 gacagataat atagaatata ctataaaaaa attatctgca agtagaagtg aaataaaaaa
    53461 taaagatgag aatatatcat attataatat tgtatttaat aatttacctg ttggaaaata
    53521 caatgtagaa gtctctggag atggatttaa gaacaaagaa attaaagaca ttgatatatc
    53581 aagttattca caaagagtct tattaagcaa tagagcaagt gtagataata aaaataaacc
    53641 tttaaattat gaattgttct taatgggtga tgtaaatgga gacggtaaag tagataagag
    53701 tgattataat aaggttttag agaatataga ttcaaataaa agagaatttg atttaaatag
    53761 agatggaaag gtagatattg ttgacttaga ttatgtacag aaaaatttag gacaaagtga
    53821 agatgcaaaa agcctagaaa gtatagtatc taccaatcct atagtagata caagtaaggt
    53881 tgaattaaaa ggaaatagtg atgtagatat taatggtaat gtagaaaatt tatttagtgg
    53941 agaaaataat ggagttacaa tatcttcaaa aaatgatgaa atatctgagg aaaaaccagc
    54001 agtaatggat atagctttat cagaagcact taatatggaa gtcatcaata taaaagctcc
    54061 agaaggtact gctccagcaa aaggaatagt tgaggttact gacaaagatg gtaatgttca
    54121 acagattcct tatgaaaaca aagaatatat gaaaaactta aaagatgagg agcaacaaga
    54181 ggaagtaaat aacgaacaag aagaagtaaa tcaagaagaa gtaaataata aagatgaaaa
    54241 tataaaccag actgataata actcaaataa taaagatgaa aataatgata aacaacagga
    54301 aaatagcgat aaacaagaag caaactctaa taccaatcaa gataaaaata atgataaaga
    54361 aaattcatca atggataaac ctaattcaga tgaagatact ccaaaagaag agggtaatat
    54421 cagtaaagat gataactcta caacatctac atatagtagg tcagcattag aaacatatgc
    54481 agatgttcaa aatagtgata tagtaataaa tcttggtaaa caagtagcag taaaaaagat
    54541 aactataaaa ataacagcta caacagcaaa cgatagaaat cttgcagaaa tatcaaaagt
    54601 tgaattttta aacaatgtat ataaagaaat accaaagcca gagatgaaca tacctaaaat
    54661 aaataaaata tcgactagca ctgctgttgg aaatgaaaaa gtatcttttt attggaataa
    54721 tgaagtaaat gtatcagcat acgaacttat actagacaaa attgatagta agggaaaagt
    54781 attatctact aaaaaattac aaactagtaa aaatacaata gaagttagag atatagaagc
    54841 atatggacta tatagagtta gcatacaatc tttaaatgga gattggtcta gtggttataa
    54901 agatgcaaca ccagaaaact tagacggagt accagaaaat gtagattcaa actataaacc
    54961 tatacaattt agcccagata gtatattaga atttcaagtt gttccagaca caaaaccaga
    55021 accaccagaa ggtataaatg ttaaaggtaa atttaaatct cttgatgtaa gctggaaaaa
    55081 tcataaacaa gctaaagatt ttgacttgta ctataaagaa aaaggctcta atgggtcttg
    55141 gataaaatac aatgataagc ttattcgtgg gacaagttca aagatagaag gtcttaagga
    55201 taatacaaca tatgaagtca gaatgacagc tactaaccac ttgggaacta gtggaatgtc
    55261 taaaacatat ataggtacaa ctgaaagcat ggatgcacca acaacaccta actatagatt
    55321 aattaatact cctaaagaaa atggtggatt tggaatacca acaaatcaca ttgtagatgt
    55381 tgtttatcca gatggatatg acaaaagtga atatagtgat aaaaatccat ttgataaatt
    55441 caatgtagta gatggggact ttacaacaca ttggacattc ccaacatata atgcagctga
    55501 gggaacgaat agaggaccaa taataacttt tgataaatct tatactatgg atacttttat
    55561 ggctacacct cgttttgatg tttctgataa gacaataaat gactttgagg tacgatattg
    55621 ggatgaaaat ggtcaattac acaatctggg ggatgttcct tttgaaacaa agacagaccc
    55681 tgtaaataat aataagtatg taatggttag attaaaagaa ccaataactg ctaccaagat
    55741 acaagtaagt gtttgttcat cctattcata taagtctaat atatcagaac ttaagtttta
    55801 tgagtatgac agtatagaag atgatgtaag aaatctattt atggatggcc tacaagttga
    55861 attaaaagaa gatgtaactc aagaaaaaat aactgaatta aaagatagat taaatactcc
    55921 agataaagct agtggagaat atcatccata taagacagtt attgagagag aattaaaatt
    55981 agctcaagac ttatataatg atagagccac acttactgat gtaactactg taaatcaaga
    56041 aataaataaa ttaggaaaat ataaagataa aaacggacag tatactgtaa attccaataa
    56101 tttaggtatg caaaatgact ggcaggcatt aggagtagct gctagagcag gagatgaaat
    56161 cacagtatat gttggaagta aaagtggaaa aactcctaag ttgatatata cacagtacta
    56221 tggagaatct ggtgcatata agagtggaga aataaatctt aacactggaa aaaatgtaat
    56281 tcaattaagc aaacttcata gtttagatat agaatgtgga ggaagtttat acataagata
    56341 cgctgaagat actccaagtg gaggagatat aaaagtacgt gtagcaggag ctactaagat
    56401 accacatctt aatctaaatg gaacaataaa tgataagagt cctgcgggag tttctgaatc
    56461 taagaaaaag ataaaagcat atatagaaga attagctaaa tataaagatg ctgtaaaagg
    56521 agaaccatat tatccaggaa caaatgttgg taattcatat ggatattcag aaaaaactgg
    56581 tgtgttaaac actacagata ttgaaagtga taaagtaaca ttaaatgttc ctgcaacagc
    56641 agtatatcaa gagatatcaa aaggaaattc tgatttaaat acacaagtag atagattata
    56701 taatagtatg cttgcatggg aacaaataat ggatttagtt tactcagaaa gaggagtatt
    56761 taaaacacaa gatttagatg gtaatggaac tgtagatgat aatgaattta acttaactaa
    56821 aaatgatatg gctccaaaat ctcgtatgaa cataaaatac caaagaatgt ttattggagc
    56881 atttatgtat gcttctggat tacatgtagg agtagaatat ggttcagttc cagggcttat
    56941 gaatggagta cctttccaaa tagatgatag tggaaaagct acaggaggaa acttatttgg
    57001 atggggaata ggtcatgaga taggacatgt tacagatatt ggaaagatga catatagcga
    57061 aactagtaac aatgtacttg ctttacttgc tcagaccttt gatgataaga cacattcaag
    57121 acttgaaggt tcaacaatgg ataagatata tgagcatgta acttcaaata gcttaggtat
    57181 accaagcaat gtatttgaaa ggcttggaat gttatggcaa ttacatctag cttatgatga
    57241 tgattttacg ggttcaatgt taaagaataa ctcagatgct gatttaagta atgatacatt
    57301 ctatgcaaag atttcaagaa aatacagagc actttcaagt agtgacccaa ttaatagttt
    57361 accaaaagac caaatgctag tagcaatggc atcaagtgtt gttgaaaaag atttaagaga
    57421 ttactttaag gcatggggag tagaaattac accagaatta aacagtataa tggatagcaa
    57481 gaactacgaa aaagaatcaa gaaagataca atatgtaaat gatgaagcta gaagaaagat
    57541 tttaaatgaa aatatagcta gtatggcaaa agatactaaa gtaagtgcta gtttttctga
    57601 tggaatacaa agtggttctc tagttaaatc taataaaata tctatagacc tagatgtaga
    57661 taaggataaa gataagatac taggatacga aataataaga agtgatggaa attatttaga
    57721 tggtgaaaat ggaacacagg taaaatacag aacagttgga tttgtggatg caaaaggaaa
    57781 tagcaagact aaatttactg ataatatatc tcctcttaat aacagagcat ttacatataa
    57841 ggtagttgca tatgattatc acctaaatcc aacagaagaa tttgaagttg gtactgtaaa
    57901 attatcagat gaagggaaaa taaataaatc agcatggtca ttcataacaa atactgtttc
    57961 tgacggtgat gttagaactg aaaatgactc acatggacca ttacaaaatc ctgaaattga
    58021 taatataaaa gataatgatg caagtactac atataaagga aagataataa gtaaagcaga
    58081 gtggaacaaa gaccctcaaa aagaccctga tataaatgta gaagaaaatc catatataat
    58141 agtagacatg aaagaaacat tacctatagt aggactaaaa tatacaaaac cagagacaga
    58201 agctagaaag ttctcattaa aaggattatt taactttaga aagaatacta gcacaacata
    58261 caatccttta actaattaca agatacaagt aagtaatgat aaaaagaact gggaagatgt
    58321 aagtcaagga acttttgaat atggacaaga tttagttggt ggaggaaaag accaagataa
    58381 tgaagctaga gttacattta ataaagatgg taaactttgg acataccaag ctagatatgt
    58441 aaaactaatc tcaaataata agtctaatat agaagttgca gaattagata taataggacc
    58501 tccaggtgat aatatagaaa ttggcataat aaataatgca gacgaaactc gtactaatgg
    58561 aattggaaaa ttagcagaag attatgtata tcaaagtgat gactctagca caagtgaaga
    58621 tgaaacaggt aagattccag cgggttcaat agttattaca ggtgaataca gtggaaatcc
    58681 agcatttaat ttaccactac ttatagataa aaacaataag actatatctg gagaagcact
    58741 tttatttgca gaagttccag aaaaaggtga actaggtgaa atcagtaaag gtacatgggt
    58801 ttactatatg ccaaaagaaa actttgattc tttaagtgat aaggttaagg ctgaactata
    58861 tagatacaat gaccttcaag gagatactcc agtaggtcaa agatttgtaa gtgatacaat
    58921 gtatgtacct gtaggagcta agaattatga tgagttaaag acaataagtc ttactgatag
    58981 taatagtaaa gctagaaaag ctacaagaaa ttctattgat atcagtaata agaaggttat
    59041 aactgtaagc aataaagtaa agggtaatat tgttagagat aaatagtagg tggaactcta
    59101 aaaacgtaaa aatactaaca ttgtatatct aataagatta ggtactagaa tagttttaaa
    59161 atagtagata ttaaaagtaa agtatataaa tgtaaccata aatttagggt aatttataaa
    59221 ttaaatataa aagctaggtg gataagtaaa tttatccact tagttaatga tagataagga
    59281 cgggtgttaa tgagtaaaag aaaatctttt ataagaacta tagcagtatc aactatggca
    59341 gtagctgtaa ctggtagtgc tacatgtgca tatgcagctc cagttttaca aggaacaaaa
    59401 acgtatgaga aagtaaatac tatagatata tctgtggact cagtagaaaa catagtatat
    59461 tcatttcaag ccagtataaa agtacaaggt gaggttgaag tagtagataa tgagcagaaa
    59521 gaaaagatta cttggtctga taatataaaa tctcagataa aaagtggaaa tgcaaatgct
    59581 acttgtagag tagaatacaa caaatcaagt aatacaacta cattagatat atatgttaca
    59641 tcaaatgaag atttactaga cggaaataga ttgaatatag gaagaatatc tgtaaaaaaa
    59701 tctggcagta actcaaatgc tgactataaa gttttaggaa aaggaacaaa tgataaacca
    59761 gctttaaaaa ttgtaacata taacaacaaa acagtggatt atgaaaatat aagctctgat
    59821 gaaggattaa tatttaccct tattaatgag agtgaagtaa aaccaattgg tggaactggt
    59881 tctagtaaaa atgaccctga aaagtataag gtagagaaaa gtgaagcact tgaatattta
    59941 ttaaacaata ttaggataaa ctattctatt gttagtaaag aaacacaaga aagtggttca
    60001 aatgtaatat taaaacttgg attagcacaa aaaacaacta agggaagaaa agctacaata
    60061 aacaaatatg ttgaagttac acttccaaaa agtttagaat acatagttga aaatgaatta
    60121 tcaaaaccgg atgaattacc accagataat ggcaatggtg gaaataatgg tggaggaagt
    60181 aattcaggcg gctcatctag tggtggaagc tctggaggag gaagttcaag tgattctaca
    60241 tctaatgtca cagtcaaaaa attaaaaggt gctgatagat ttgagacagc tatcaaaata
    60301 tctcaaagtg gttggacaaa atcagataca gttgtaatag taaatggaga agataaaagt
    60361 atggtggatg ggcttacagc tacaccactt gctagtgtaa aaaactcacc aattctttta
    60421 tcatcaaatg aaaagcttcc tcaaaaaact gtagaagaat tgaaaaggct aaatccatca
    60481 aaagtaattg tgataggtgg aaacaactca atgccaaatt cagttgttga agctatcaaa
    60541 gctgtaaatt caaaaatatc agtacaaaga ataggtggag atacaagata tcaaacttct
    60601 attaatatag caaaagaaat agataagacg aataatgtaa gcaagttgta tataggagca
    60661 ggaaatggag aagctgattc attatcaata gcatcactgg ctggtaaaga aaaaactcca
    60721 atagtactta cacaaaaaga tggtgtagat aatgaagctg aacaatttat taaatcaaat
    60781 aaggtgtcaa atatatattt tattggtgga gtagaaaaaa tatctaacaa ggctattgaa
    60841 caagttggaa aaatagcaaa caaagatata tcaaacaata gggtggcagg tcaaactaga
    60901 caagagacga atgccaaagt aatagataaa ttctactctc aatctaagct agatggagtt
    60961 gtagttgcaa atcaagataa acttatagat gctttagcag ttggaccatt agcagctaaa
    61021 aacaattcac cagttatact tgctacaaat acgttagata aatcacaaga atcgtcatta
    61081 aaaggtaaaa attcatcaaa gttgtttgaa gtaggtggag gaatagcctc atctgtaata
    61141 gacaagatta agagtttaat tgaaaaataa atattaagta aatagaaaat aagaatgtat
    61201 ttagatataa agttatatat ttaaatgcat tcttatttta ttttcattat cttaacaatc
    61261 taataatatt gaggttaaaa tgtata
//
LOCUS       DAMKNB010000016        58662 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.016, whole genome shotgun sequence.
ACCESSION   DAMKNB010000016 DAMKNB010000000
VERSION     DAMKNB010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 58662)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 58662)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..58662
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.016"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            140..490
                     /locus_tag="PC494_001141"
     CDS             140..490
                     /locus_tag="PC494_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HDF3911661.1"
                     /translation="MSAKVTNQYGNIEIDNQVIAQVVYRAAMESYGLVGLAYKSKGIV
                     ELLKGENATKGVRVEEVEEDAIAIELYVIIQYGTNISTVANNIIDRVKYVVEKMTGVR
                     VTRIDINVQGIRVK"
     gene            509..2152
                     /locus_tag="PC494_001142"
     CDS             509..2152
                     /locus_tag="PC494_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HDF3911662.1"
                     /translation="MIQYIDGKRLREMFISGANNLQNNKELVDKLNVFPVPDGDTGTN
                     MSLTISYALKELAKVENDNISDIGKALSKGSLMGARGNSGVILSQIIRGIAKSIEGKS
                     KLSTEDLAKAFKNGSDTAYKAVIKPIEGTILTVVRESGEFAIKTAKKEKDVVKFLSML
                     VKESNSSLERTPDLLKNLKEAGVVDSGGKGLVLIYEGMLASIKGDNIEIKNVDLDTNI
                     STSMDFAKSTTSTDDIKYCYCTEFILESSKVEDTKIRDIMMAYGDSLAVVGDDGVIKV
                     HVHTNDPGNVLQEALKYGQLLTIKIENMKLQHENTLLDVEEKKENDSEPLEEEKEFGF
                     IATSMGEGLANIFKDFGVDHIIEGGQTMNPSTEDFMNAIKHINAKNIFIFPNNSNIIM
                     AANQAKELSDKNIIVIPTKNTPQGFAALVTFNGELSEDENKEAMMNALNSVKSGQVTF
                     AVRDTVMNEIDVKEGNIIGIAEGNLLSAGDYVDEVTSNLIEKLVDEDTAIITLFFGED
                     VTESQANELRTSLEEKFEDVDVELYYGGQPLYYYLISVE"
     gene            2233..4290
                     /gene="recG"
                     /locus_tag="PC494_001143"
     CDS             2233..4290
                     /gene="recG"
                     /locus_tag="PC494_001143"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HDF3911663.1"
                     /translation="MDLYKDVQYVKGIGPKKADKLNKLGIFTLKDLLYYFPRQFEDRN
                     NLKKIAQLEDGEKVTIKAVISSINTFSPKEGMTLTKIDVKDETGSAKLVFFNKSYIKN
                     TFRPGDSILVFGKVKKKFNNLELTSCELEYLTNSPKNTCRFMPVYQLTYGVTNKEIMS
                     IIRTVLEDKELIIQEYMPQRIIEKYRLCSIDFAVRNIHSPSSKESLKIALYRIVFEEL
                     LILQLGLFVFKSGRNKEDGIKFETSKDLKKIISALPFKLTKAQNRALDEIIQDMNLEK
                     IMNRLVQGDVGSGKTVVALLALANCVLNGYQGALMAPTEILAGQHYISLTESLKDFGI
                     NVGLLIGSLTKKQKDTVLEQIKNNEIDILIGTHALIEDKVEFNNIGLVITDEQHRFGV
                     MQRSKLSLKGANPDILVMTATPIPRTLALILYGDLDISIIDELPPGRQPIETIAIEKS
                     KRDRAYNNLVRREVESGRQVYIVCPLVEESEAIEAKSAVELVEELRAEYFHDLRLGLL
                     HGKMKSSEKDEVMRLFKDKEIDILVSTTVIEVGVNVPNATLMIIENAERFGLAQLHQL
                     RGRVGRGSHKSYCVLIYDSKTDVCRQRMAIMEETNDGFKISEKDLEIRGPGEFFGTRQ
                     HGLPELKVANLFKHIKILKLAQQEARYILGEDNNLQLKENMALKKEIIDKFKDTLKEI
                     SLN"
     gene            4349..4903
                     /gene="rsmD"
                     /locus_tag="PC494_001144"
     CDS             4349..4903
                     /gene="rsmD"
                     /locus_tag="PC494_001144"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HDF3911664.1"
                     /translation="MRVISGKARGLKLNTPKNEDVRPTTDRVKESLFNMINSYIMESE
                     VLDLFAGTGSLGIECLSRGAKSCTFVDISKESIDIVKSNIKKARVESESIILNLDFKT
                     AIDKLKLQNSKFDIIFMDPPYYKNMFIEAIEKIDNSNLLNEDGIIVVEHDTNDLFPDK
                     ICKLEKTRDKKYGNTTLTFYKMEA"
     gene            4905..5402
                     /gene="coaD"
                     /locus_tag="PC494_001145"
     CDS             4905..5402
                     /gene="coaD"
                     /locus_tag="PC494_001145"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HDF3911665.1"
                     /translation="MENKPRKAIFAGSFDPITNGHLDIICRASKLFDELQIGVLNNPN
                     KKGLFSFDERVKLIEKSTSHLNNIKVVTFDGLLINYCQENGIGALVRGVRSGADVDYE
                     LQMAHMNRELNPDIETIILPSCTKYSFISSSLIKEVLLFDADIKNLVPKIVLEELKKK
                     TSGGN"
     gene            5406..5930
                     /locus_tag="PC494_001146"
     CDS             5406..5930
                     /locus_tag="PC494_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3911666.1"
                     /translation="MKIDLEMIELFEQLEEIFRSASTIPFSHKCTVDKDEVLAIINDI
                     RTLIPEEVTQAVWINKERNKIISQAKQDATNIVEQAKKEAERIQQEYQDNIEELKKNS
                     EDVVKAYVESSEPVVQADQRAKDIVDRAERIANEIRIGSIEYAEDVLSSVEYNLREIL
                     EEVKRDKAELRPKK"
     gene            6274..8193
                     /locus_tag="PC494_001147"
     CDS             6274..8193
                     /locus_tag="PC494_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HDF3911667.1"
                     /translation="MKERAKKILDFIIKNNNVTSQELQEKFNVSKRTIYYDILAINEQ
                     LGKSGNIKNVKHKFIFEGNLCDARKIISTEEDKFLDSDYRKTFILNKILLGEKISIEK
                     LTNEMLLSKNTVVQTITDVKKYLQTMGLRLEYKGKYKIIGDEYVIRELFLIIVQENIL
                     EINSISEEVSSFDTKGHIKLTDYSLLNLTKFVEFLNKRIRDGKTLYSYKYLNEAKKIS
                     YFSNCKELLCEEANENEQAYICTYISSLPSLNSEVKEDVVEEYVDKLIDKFEVNTAIK
                     LESKHEFKKNILRHLHSSYNRIRFKFPIRNPMLDETKYKHESLYKIIKSIIENEEEFP
                     VFEGIREEEIGFIAAYFGGYLRGSRDNGLRRNKVLLVCPNGLMVSKSLEIQLYKYIPT
                     IEIVGIVSIKQLKEVNVYYDYIITTIDIQNVNNVIVVNPLLTSSDVQLLMNKLISVKE
                     NEKYFNLELIIQAIRKNGVINNEEALKADLLNIIHKIDEGEMYQPMLKELINAERVNI
                     IKSVRDWKEAIKIASKPLLEDNSIEELYIENMIKSVEKYGPYIVLADRFALPHASSKE
                     GVNKLAMSLLIVEDEVDLLGKPVNIFMVLAAVDNTTHIRALASLSEMMYEEENVKLII
                     NGDKSSILELINKQN"
     gene            8206..8493
                     /locus_tag="PC494_001148"
     CDS             8206..8493
                     /locus_tag="PC494_001148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDF3911668.1"
                     /translation="MKILAVCGFGVGSSMVLKMTIQKALKQLGIECEVENTDINSARG
                     ADCDCIFTSQELLNELKGTCNVDVYPVKKYMDLAEVTEVVQTFLSDKNDKK"
     gene            8626..9885
                     /locus_tag="PC494_001149"
     CDS             8626..9885
                     /locus_tag="PC494_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HDF3911669.1"
                     /translation="MLDFISNNILRNPSMLIGLIAAFGLVLQKKKASDVIKGSLLAAF
                     GIIIMETGTGMLVSSIAPINGAFQSISGGAVTKGLSDVTFTASYGGIIGLAMFAGLAI
                     HLMIARFTPIKTIFLTGHMLYWFPFIFVASGVEAGLNGGVLIAFAAVLSALYWSIMPW
                     LLRKYVFDVIGDDSFTLGHPSGCLALISGFVAKLVGNKEKSTEDINIPQSLSFFREIS
                     ISGGMAVFLMFIVVGIVIPGAFKDSNEFIGTYAIKQGLSFGAGLIIMLHGVRMLINQI
                     MPAFQGISEKVVPNALPAFDCPILFNYKPNAVLMGFLVAMLTSTAMILICNYFNVFNL
                     LLIPLVITSFFECGAAAVIGESQGGIRGAIIGTAIAAIFMVVLVGISAVIYSGTIQNW
                     ILIFGGNDLSLFGIISRFIGSLFGGIL"
     gene            9888..10628
                     /locus_tag="PC494_001150"
     CDS             9888..10628
                     /locus_tag="PC494_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HDF3911670.1"
                     /translation="MKFKYIDEIRRLIDIIENEEKVNMEKAVQIFVEAIESKNAIFSF
                     GASHAGILTEELFYRAGGCVLINPVFAKSLMLDTAPITHTSKMERLEGYGTALADKTP
                     IKKGDVVIVHSVSGRNPVSIEFAMKAKENKAIVICITNLSYSKSVSSRHSSGKKLYEV
                     CDLVIDNHGQKGDACVEIDGLNQKVSPTSTVIATTVMNSIIAQATQELVNKGLKNPPI
                     FYSANIDGGDELNKKIFDEYKSVIHYEY"
     gene            10951..12261
                     /locus_tag="PC494_001151"
     CDS             10951..12261
                     /locus_tag="PC494_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HDF3911671.1"
                     /translation="MKKENKMEGIKVGMLKKLCSLAMVAIMTTTLITGCSSGNGKDSK
                     KDGEKEKLVLWMPPVENNMKEVWDPILDKFEEKNNCEVDLQIIPWDNYSEKFATAISA
                     GEGPDVGYMYAEMYPQFIESGAVEDLTNYATKEDKEQSIYIKTSEMMGGMYGMPFQAA
                     NPGVLYYNKDILEKLGEKPPKTWEDFKRICKKATQDTDGDGKIDQWGLAQGWGAKTFG
                     NLNWNWYPYLWQAGGDIFNDDLKSVKFNDKSGLEAANFLKELQAYVPEDSLSKDSNEM
                     IESVFGPGKAAFTIMLSSAATSVFDESFPDLNWGFVTGLEDKKAATFGAVDHLSLMSS
                     AKNKELAYKLIQHMLSVESMTEFHKAIPRAPITKGEPYQGDERFKEMVENDKNVYRPL
                     VVGPHGVEIYEYLWKELQTMISGDKTPKQALDDAAKYSNDLLAQ"
     gene            12359..13276
                     /locus_tag="PC494_001152"
     CDS             12359..13276
                     /locus_tag="PC494_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HDF3911672.1"
                     /translation="MENLVREFEENSKRKKTKLNIKPYMYILPLGIILVAFYVIPIIM
                     SIYFSFTKYNIISPATFIGLENYKKLFTDETLKVSIINTIKFTVVVVPCQTILSLILA
                     VWITGKGNSKIASFAKGAIFIPVLSSMVLIGMVWRALLNGEGSIIYQVLGAFGIESSK
                     LLGDSKTALPTLMFISMWKNIGYFMVIYISAIMNLPKHCYEVAKVDGATKLQEFIKIT
                     VPLLKPTTIMVVFLGSIWSLQVFDLIYTVTGGGPGISTMSIVMHAFNLNFKNFNSGYA
                     MTVANVLFLLIAVVSILQNKLVRRDNSDF"
     gene            13292..14101
                     /locus_tag="PC494_001153"
     CDS             13292..14101
                     /locus_tag="PC494_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HDF3911673.1"
                     /translation="MKTARRLLSDGLLLFIACASLVPFIYMLIISLKITYNSYSLDIS
                     FSTVTLQNYIDIFTKKGFAQYFFNTAIVSFSGVLLNLVFSTLAGYSFAKMDFKGSDKL
                     FLFMIMTLIIPSQVTMIPLYIIMKHLGWINSYLALIMPIPTAFGVFIMRQAILGVPKE
                     LLESAKIDGCSDFRILIQIVLPLIKPALITLAIFTFMGAWNEFMWPLIATTKDAMRTL
                     TVGLSTLKTFQITNYGQMMAGATITFLPPFIFYLILQSKFVEGVSLSGIKG"
     gene            14159..15907
                     /locus_tag="PC494_001154"
     CDS             14159..15907
                     /locus_tag="PC494_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4091 domain-containing protein"
                     /protein_id="HDF3911674.1"
                     /translation="MEISYVLKDCTFKHNKYSVVEAETWKDKDLDIVVAKGEKFAFQI
                     MLKATEEFNCTIDKSSAISWKGLGNRVRLALNMPNSLENNFSINILGYVQDDTKAFVN
                     DAILRDKDVLVEQYLPQTFWIEGQVPEDFEENNLDIGIDIFKSFGYEDEEKVCTIDVP
                     VKVRNVVLKPLDESKFFLDLWQHPSCLARMYKVELWSDIHFEIVDNYLKELASLGEKV
                     ATVIVSDYPWAGQSCYKVYKNPSNLYEYNMVSVSKGLDGKIKCNFESMDRYISIADKY
                     KMAKEIDLFGLLGNWCAGEFGNPVEGYKDPIRVRYFDEKDKVFKFINNTNDLKEYIGL
                     VLNHLIECGLWDRVRIIADEPNNPEVVKECIEFINSTVGTHQVKYKSATHDQNFLDRA
                     KDEIDDMSINLKLTIQNYKDIESLKKKINDKGGILTWFVCCFPEKPNSFLSSPFVENR
                     IIGWYTYYFGLDGFLRWDYNLWTEDPWKDSSYKFPIWKAGDMFFVYPGKDLKPVRSVR
                     MENLRFGIQDFELFTMLEKEKGREYIEVELMQELLNKKENAEIKGFGDIELGYSLDNW
                     GYDKVKKYVLELLDRV"
     gene            16169..17191
                     /locus_tag="PC494_001155"
     CDS             16169..17191
                     /locus_tag="PC494_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 5 protein"
                     /protein_id="HDF3911675.1"
                     /translation="MFGGINIKRIGIIIMFFLSISFIGFYLVIRDNSDTVKMQRGINI
                     GNALESPKDFPWDVKMSNKFFDDIKDAGFDTVRIPVRFSDYTSDSDNFKIDEEFFKKI
                     DKYVDYALDKDLIVVLDLHHFEEIMKEPRVHKEKFLKIWQQIANRYQKYDKKLVFELL
                     NEPKENLYSQLLNEYIEEAIKIIRKTNPKRTIIVGPYNFYQIDYLNELNIPKDSNIVV
                     SFHYYEPNDFAFQGNIYHKGFEHLSNITWEGTNEQMDYLKKRFDTVENWANKNKVKIF
                     LGEFGITKEAPEASRRAWIKAVREEAEKRNFSWAYWELASGFGIYNQIEGTWDRDILS
                     ALIEKR"
     gene            17196..19502
                     /locus_tag="PC494_001156"
     CDS             17196..19502
                     /locus_tag="PC494_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HDF3911676.1"
                     /translation="MKKNSKKILITLTIITNVIYILWRIFYTVPKEEGKFALICAIIL
                     LFVEIMGMMEMFVHYYGMSNIEYPEKPIISEELYPHVDVFIATYNESVDLVRKTVNGC
                     IHMQYPDKKKVHIYICDDGNREEMCILAEKMGVNYITRTEREGAKAGNLNNAMQHTNS
                     PLIATFDADMIPMHDFLIATVPYFLKNEQAKKDGEKEEYEKVGFVQTPQSFYNPDLFQ
                     FNLHSEGRIPNEQDYFYRDIQLARNRTNSVIYGGSNTVISREALEEVDGFYTYSITED
                     FATGILIQSKGYRCYAIPEVHASGLSPTDLKSLIKQRERWARGCIQTGRRLNILFRRG
                     LGFWQKISYISSITYWYASIKRFVYIMAPILFSVFNVIVVKCTLLQVLVFWLPMYILS
                     SLSLKIFSQNIRNTRWTNIYETIMFQSLMPAVILETFAISKNKFSVTNKSKLEENRMY
                     KFLQGIPYFIYMVLSIIGILKMFVAIFKMSSMTYSVVLFWLIGNLFNLVMATLFISGR
                     QQLRKSERYIAEIDFKLKQNSYVLSSKTIDISENGFAFLLENPEYISPEEEFEVEFRE
                     KSGNEMYIANMKAKIVNVVEVNSKWKYAAYITHIEDSEIDNWMCIVHDRIPTLPMTIS
                     NQLGFFDDLQINVKKRIEKTRTLSRRSPRINMNFQMDIKNTGKLRIVNFNYQYVLLNF
                     ENKSIYPKEIALEINENIVLECDLCEGKIDERGILYKVNNIDSIMQNFFLRDEMMDWI
                     LQNKKILDSKPSEKKEKSIDEFEPMEYI"
     gene            19474..20589
                     /locus_tag="PC494_001157"
     CDS             19474..20589
                     /locus_tag="PC494_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3911677.1"
                     /translation="MSLNPWNIFRRDEMKTLKVFFCSTKYLILVFIFFINTTFISSAT
                     SDKILDLSFKKIETDLSSKITYEDTGVKIETDSSKSDKERYLYIYQNIKENWSMYNNF
                     YIEIQNKNKSSQRINLSIQSKNMLEFRLKEGSEVFLEGKNIIYSDKIKEGCIEVPGEF
                     EGKIYVNFNSLINEESNVVLDSNMLSNIVSWGITFIPSDEEHNIVIIKKISLLSEEKL
                     RFLNNIKIIGDEEVQIPVLGQSISQYEVLGLKSDSKIKYSLMGKQDNVSISQKGKLTL
                     SNKAKPGQIILQVNVDDKFKIGKKITLTESWSVNKKDKDGVPYTLVYPEQSPTVQDMK
                     KINFMNNIITFVRILFVSLVIICFGIYLYWKKCSKTK"
     gene            20607..22025
                     /locus_tag="PC494_001158"
     CDS             20607..22025
                     /locus_tag="PC494_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBOAT family protein"
                     /protein_id="HDF3911678.1"
                     /translation="MLFSSLIFLFYFLPITLVLYYVFRFNRTIQNMILLAVSLFFYAW
                     GEPKFVVIMIVSIIMNYIFGLLVDRYRESKIKVKVFLVLMCAYNIGVLFIFKYLAFAL
                     RNISELISTELTIPSIVLPIGISFFTFQGMSYVIDVYRRHGEVQKNPFYVGLYIAFFP
                     QLIAGPIVRYESVAEQILNRKETWNKFSIGTCRFITGLGKKVLISNNMAIVADYIYTM
                     NSQGEIAASLAWLGSIAYTLQIFFDFSAYSDMAIGLGLMFGFKFEENFNYPYISKSIS
                     EFWRRWHISLGMWFKSYIYFPLGGSRVANKDIMIRNMFIVWLFTGIWHGAEWTFVIWG
                     ILNFVFLIIERFIMFEKIENHNFIKHIYALLVVNFGWVLFRSPNLKEAYNYFKAMFGG
                     NGAIWSDYTYMFLKEYWVFFIFAFIFSVPIAKKINKFVVEQAKYSMIFNVFYPISAIL
                     LFFISVTYLVTGSYNPFIYFNF"
     gene            22040..23248
                     /locus_tag="PC494_001159"
     CDS             22040..23248
                     /locus_tag="PC494_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3911679.1"
                     /translation="MNRFFKVRLITAIMFLIILFAFSIFNVCYSGKDTIQEIKNSIAE
                     KSSLKDTISSIDNTVNDKVIYKNTFIETYGYLQKLMGKNEFSKFSVVKDTSGKMHYTY
                     FAKAPNPVGVIADRVRKFSDEMEKQNTKLVYLMTPDKYIKGVTKFPKGIPYSYSNETA
                     DNFLNQLKKYNVDYIDFRENILKSGIPKDDLFFKTDHHWKVETSFWAFGELVEQLNKK
                     YNMNLDENHYYRDKDNYNSIVYPKSFLGSMGRKTGILYGGIDDFTLIYPKFKTNYTYY
                     TDSKSQKFELKGRFEESLILSYPFNADLDLMDGQSDKYFTYLLGNRPLVKIKNIENPD
                     GLKVLFVKDSLIVPTAAFFSSVCSSIDMIDPRYYDGDILEYAKSHDYDFVFISVYPQN
                     LTKEFFPFCE"
     gene            complement(23322..24710)
                     /locus_tag="PC494_001160"
     CDS             complement(23322..24710)
                     /locus_tag="PC494_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:dicarboxylase symporter family
                     transporter"
                     /protein_id="HDF3911680.1"
                     /translation="MESSFLSQFLMITDFKTIFFIILLLGTFFIVRQFEKKKIKFSLR
                     TIYATVLGLILGIIIQAFAGFPNDTTQVIWLQEVSKWYSLFGSGFMDLLKMLVVPLVF
                     LSIIKVIINMKDNNLGTLTFKSLGMLLATTAIAAIVGIIVANIMKLGVGANMPTLVEN
                     QELKEINSLVDTLRGLLPSNPVMAMANGNIVATIIFATFIATSIKRLSKKHFETIKPF
                     IGFIEASYKIIVSVSMTVIKFMPYAVVALLANTITSQGISSIVSVLQFILALYISVAI
                     LFIIHLIFITLNGLNPITYIKNSTEALLLAFTSRSSLGTLPVTIESLVQNHGVDEGVS
                     SFTASLGANMGMNGCAGIYPALMAVTLANMAGVNMDMSFYVMLLIVITISSFGIAGLP
                     GTATMAVSVVISGVGLGSYFPLVGGILAIDPILDMGRTMINVNGAMVSSITVGKSLGK
                     IDKEVFSKKNIS"
     gene            25051..26385
                     /locus_tag="PC494_001161"
     CDS             25051..26385
                     /locus_tag="PC494_001161"
                     /EC_number="1.8.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-disulfide reductase"
                     /protein_id="HDF3911681.1"
                     /translation="MRVIIIGGVAAGMSAAAKLKRIKPEYEVVVYEKTEIVSFGACGL
                     PYFVGGFFNDADELLARTPEKLREAGIDLNIFREVVEVDSESKKIKVKNIKTDEIYED
                     YYDKLMIATGARSIMPPIKNIKLKNVSTLKSLYDGEYLKKLLSNEDNKRVTIIGAGFI
                     GLEAVEACKKLGKDVDVIQLEDRILPQVFDKEMTDVLEEEINRHNVNLHLDEMVVELC
                     GEDKVEKVITNKGEIDTDVVIIATGVRPNTEFLSNTNIKMLKNGAIVVDEYGRTSVED
                     IYSAGDCATIKNIVSNENVYVPLATGANKLGRIVGENLAGREISYQGSLSSSCIKIMD
                     MEAASTGITERQAKDLGINVKSKFISDYNQTHYYPGRNKIYVKLIYDADTKVILGGQV
                     AGFKDAVQRANVLAAAIFGKMTTNQLGMLDLCYAPPFARTWDVLNVAGNVSK"
     gene            complement(26527..27444)
                     /locus_tag="PC494_001162"
     CDS             complement(26527..27444)
                     /locus_tag="PC494_001162"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011969064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HDF3911682.1"
                     /translation="MIDLTLLGCGGNVPMPNRFLSSVFINYKGRKILIDCGEGTQVSM
                     KLKKCGFKDIDLICITHLHGDHIFGLLGLLSTIGNSGRTSDLTIVGPVGIVDCIRSMR
                     NLVEYVPYTLKIIENPQGNFSLDNKVLRNLEISTISLEHSIECLGYSFNFRRNPKFDI
                     DKATKNEVPKILWNKLQEGQNIVLDSKQYTPDMVLGELRKGVKISLTTDTRPIESIPD
                     FIKDSDLFICEAMYGDDLDISKAVRNKHMTFREAANLAKLGNVKQLLLTHFSPSLDIP
                     SMYLENATNVFENTILGEDRLSLRLNFDE"
     gene            27652..28536
                     /locus_tag="PC494_001163"
     CDS             27652..28536
                     /locus_tag="PC494_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4846 domain-containing protein"
                     /protein_id="HDF3911683.1"
                     /translation="MKVLKKITILSLITLTLVGCSNGEDKKVVEGSKKIQNSKKDEQP
                     IIVHKDANILKDRYEPPKGFKRVDVEKGSFESFLRNTKLKNYGEKVKYYDGRTKESKG
                     IYDSVFDVDIGNRDLHQCADAIMLMRAEYLYQNKLYDEISFDFVDGFKAKYSKWAQGY
                     RISVKDSGSSWYKATEYSTSYESFRKFMDIVFAYSGTLSLEKELEPVKVEDMKIGDVF
                     IVGGSPGHASIIMDMAENEKTGEKVFMIAQSYMPAQQTQLLINRKNPNLSPWYSLDFE
                     GDLTIPQWTFKRDQLKRF"
     gene            28749..30590
                     /locus_tag="PC494_001164"
     CDS             28749..30590
                     /locus_tag="PC494_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional metallophosphatase/5'-nucleotidase"
                     /protein_id="HDF3911684.1"
                     /translation="MKIRRYLILVIIILITTSQSFISYGLERFEEITIFHTNDIHGRY
                     AEGDDHIQIGNLATLKKETPNSILVDAGDCLHGLPIVNMDRGKSAIELIKCAGYDYIT
                     PGNHDFNYGKDRLFELSKSANLGENTLKFLSSNIFENGKKVFDSNDIKEIDGIKIGFF
                     GLSTQETKSKTGFKNVEGLEFKNPIESATEQVNELKGKGANVIVAICHIGTNSLSKPN
                     SIDIANEVQGIDLIIDGHSHTKFENGKQVGDTLIVSAGQYLENIGEIKLTLDTNDVEN
                     IKIENKSVRLIGKEEALKYKLDSAVSKKVDEIKEQQEKILDKVIGVTTNTLDGSYENV
                     RTKETNLGNLISDILLDKTKADISLFNGGNIRDTIEKGNITRRDIVDVFPFNNTIVTK
                     ELTGAQIKDVLEHGVKLYPEKSSAFLQVGGISYYFNPKQKEGEKITNIQKEGKPLDLN
                     KKYVVATNDYIASGGDEFPCFSKEPVLKEFGNLESAVIEYIEYKTEISKNVDGRIGIK
                     SKDELISKNHESDLILSENEKNINDNEENLSNNIKSSDSDKNKSLDKTSARESSNLGI
                     SKREAKEKSPKTGDLGFSNSIIIFIVSSTLICLLNFNQKELKDKKSK"
     gene            30895..31602
                     /locus_tag="PC494_001165"
     CDS             30895..31602
                     /locus_tag="PC494_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF3911685.1"
                     /translation="MNNILLLEDDKSLNRGISFKLKKEGYNVFSAFGIEEAKNIFAKE
                     EICLIISDIGLPDGSGFDFCEEIRKKSDVYIIMLTALDEEVDIVTGYDLGADDYITKP
                     FSLMVLISKVNALMKRVNTVKNYTLLVCDDLFFYYIENKLIIRTDDKEEEIILSKTET
                     KLLKYLMENSMQTLTKEQLLESLWDSSGNFVDDNTIAVNIRRLRQKVEKNPSEPKYIK
                     TVRGVGYMWGERSIKKC"
     gene            31596..32906
                     /locus_tag="PC494_001166"
     CDS             31596..32906
                     /locus_tag="PC494_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF3911686.1"
                     /translation="MLKNMNLKDGLSVKDDYIMRRVIVYSVLSVLIVTLVFILFEYSR
                     LHKLYEHQIKNTQNIAGILIEKYPNDEIDIVNSIYNSDYSKVSTGEKAFKKFGYGLEN
                     KMSNDKNFSLYLKSFFKESFFIFLMMFIVVIGIIYYFIRYINKRLSKIYFIVDKMSQE
                     NYLKDTTESEETGYLVEYNEYFKEGIFSKINNCLYELNRSLKIKFIKLEKEKESVKSL
                     VTDISHQLKTPLASLKLYNTLLIEEELEEDEANEFLLTNKASINKLENLINSLVNISR
                     LEISMINIKKEDNDIKNTILNAVKSVTPKAKSKSITLNLNEFNSRIIPHDKKWTEESI
                     FNVLDNAVKYTQVNGEINISVEETANFFKIIIEDNGIGIEKNEFNNIFKRFYRGSADE
                     IESVEGSGVGLYLSRKILEEQGGNIIVSSKVGIGSKFSLFLTTM"
     gene            33023..33706
                     /locus_tag="PC494_001167"
     CDS             33023..33706
                     /locus_tag="PC494_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF3911687.1"
                     /translation="MKILYTENLSKHYGKGESLVRALDNVDLEINEGEFVAIIGKSGS
                     GKSTLLHMIGGLDIPTSGKVYIDNKNIFTLKEEELAVFRRRKIGFIFQSYNLIPSLNV
                     WENVVLPIGLDGREVDESFIKELLKSLGLENKHDVLPNTLSGGQQQRVAIARALATRP
                     AIILADEPTGNLDSKTSDEVMSILKSMSKKYSQTLVMITHDDSIAQMADRVIFIEDGR
                     VSKVGDKND"
     gene            33699..36086
                     /locus_tag="PC494_001168"
     CDS             33699..36086
                     /locus_tag="PC494_001168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HDF3911688.1"
                     /translation="MINTTKIAKSNLKQNKSKSILIIITIILSTLMLSSIGIYIVDAG
                     AYQKENTIKYSGNYQGILANVDEKQADILSNHADVELTGEMNGVGVEKLEDDSNISLA
                     YMNEDALKLNSFEFIKGKLPSKENEIVLDSGALKALGYKNKDLGEKIKISYDDYKSDK
                     KIEKEFIISGILKTSEISEAGKYYYAIISESYMRNTRDMSQEDFNIYVKLNDKSNLSI
                     EQAKSKLNKIANDVGLDTINVAVNENYINALKPDMETIMGGVFVGLVIVLSSILVIYN
                     IFYISIVTKVQEFGKLRAIGATKKQVKNIVFKEGFILAGIAIPIGIILGYVLANIIIK
                     SFMDIDVKSSRLPVILSVVVISFISVVLSLLKPMKVASKVSIVDAVRYTGNKISNKSK
                     RKGYKNINLKRLSHANLERNKKRTYMTLASLILSGTIFITVSTALESFDAEKMAREHF
                     PYDIEVRLSGYEMNSDKNPKDNLNILQMDNPLSKDFFNQIKNMEGIKRIESARSVKIG
                     MEDYDVEFKYDLLQSINENDVKSLNKNIIDGKINLERLQTGDEIVITHVDTAKEMGVK
                     AGDKIRLTLYDGDKKIKKEFKVQAIAMGVPSFGIGKDFIDRTLKYDSTSSLGIYTEEG
                     KYQEIKDSIKKIAKNNGFLETDFIDSRIESNKATISFIKIMGYTLTGIIGVIGFMNLV
                     NTMITSIVTRKKELGMLQAIGLTNKQLVKMLNSEAMYYTSGMMIGSILFGGILGYIAV
                     IFLKKTGLSYATYSLPIVPILLMIVCILIAQFITTYLIGRSFNKESLIDRVRYSE"
     gene            36366..37508
                     /locus_tag="PC494_001169"
     CDS             36366..37508
                     /locus_tag="PC494_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--glyoxylate aminotransferase family
                     protein"
                     /protein_id="HDF3911689.1"
                     /translation="MNKKINYAPGPTETRENVRLARAEKTTNPDIDIDFVEFYKKTCE
                     KFGNIIGTKNDVYILSGEGILGLEAACASLTEKGDRVLVIDNGIYGEGFKDFVTMYGG
                     EYVLFSSEYTKSIDIDELKAFLDEDSNFKYATVVHCDTPTGVLNDVSKICPLLKEYGI
                     LTVVDSVAGMVGERLSVDESKIDIILGGSQKAISAPAGLTIVGISQDAKNCIKNRKTD
                     VIGFYCNLNIWEGYYEKKYFPYTMPISDIMGLDKALDNILEEGIENVLNRHEKIAYSV
                     RKSIEEYGLELFLEEGYSNTVTAIKIPESIGALELTDYMLKNYNTLVATSLNQYMDTI
                     LRIGHMGENANLNKIEHVLNVLDKSLSALGFKGNGNLLNLFNKYYF"
     gene            37527..38051
                     /locus_tag="PC494_001170"
     CDS             37527..38051
                     /locus_tag="PC494_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HDF3911690.1"
                     /translation="MEVTAKQKFTTKDMVETSLLIALVFIATKFINIRLPISINGGLV
                     HLGTAMLFISAIVFGSKKGALSGAIGMSLFDLISGWTLWAPFTFIDRGVMGYLLGKIA
                     WANGNNGNNFLINVIGICVSSIWMLFGYYVTEVILYGNFIVPLTSIPGNLMQVLIGLI
                     IALPISKVLKKCIK"
     gene            38151..38969
                     /locus_tag="PC494_001171"
     CDS             38151..38969
                     /locus_tag="PC494_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HDF3911691.1"
                     /translation="MLSVTRYSIKNVRLKPWVKFIWYFETKSNILLNNKLLPTDSIDI
                     ILNLSDVMEYKIENQDYIASNIHFNGIRDKHGFIIQHGNIRVIGISFYPFGLYPFLKI
                     PISEFNRQIVDLEAVSKLFAKKLEESLNPTKAIEKVVLCLEEVLLSILEEDLISNKYV
                     KLLNSFIYVNRYSNIKAFCDDTNINIKTLERICLKYTGYTPKILKRIYRFKMASNQLI
                     YNYKDDELFDFIYENEYYDQAHFIKEFKKFSGTSPIKFSGENKTIKENIKYSYL"
     gene            39047..39358
                     /locus_tag="PC494_001172"
     CDS             39047..39358
                     /locus_tag="PC494_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antibiotic biosynthesis monooxygenase"
                     /protein_id="HDF3911692.1"
                     /translation="MKIITEIVEFNVEENLSKEEFIEIVNDLELKFHSIQSGFIDTEL
                     LYDEKSQKWIMIQHWESIEDLKSVSSKMFKDSSTEKFRKALKNQTVKMNIIPQIKSWK
                     L"
     gene            complement(39535..40218)
                     /locus_tag="PC494_001173"
     CDS             complement(39535..40218)
                     /locus_tag="PC494_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3911693.1"
                     /translation="MQKEVAMNKLIKDCVNFFNDCGFSYSICGGYALELFANMHIRPH
                     SDIDIWISDTDKEKSIQYMLNQGWDIYEPLGNYLLRPIIDLNKQHIEQICVFAIKPDC
                     SFIELKKVEDDNYKMNIQCDEQLQFDFIELIYNPQKDGKFLFSQNQRIIRDMDKARLI
                     TSDNIPYMAPEVVLFCKSIYIDRLGYQKDFDVTVPLLSQEQRDWLVNALITAYPDGHA
                     WIDQLANQY"
     gene            complement(40311..40952)
                     /locus_tag="PC494_001174"
     CDS             complement(40311..40952)
                     /locus_tag="PC494_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDF3911694.1"
                     /translation="MGRKKEPDNTIQKILDISHKLFLEKGYEQTTIQDIVDNLDGLSR
                     GAIYHHFKSKDEIIKAITSRLYNDGFYGYEVKNDEGKTALEKLQYRLLHAYEQHNKQD
                     IFLMSSSLLRNPKYLATQFDEIINDIVPWIKALIEEGNQDNSMEVKNPEIAAQMFGFL
                     LNTWCIPTVYPGNPQQMIERFTLFGEQAAFMGISFMNDKIMCEYQKFVNKFSK"
     gene            complement(41126..43129)
                     /locus_tag="PC494_001175"
     CDS             complement(41126..43129)
                     /locus_tag="PC494_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha amylase C-terminal domain-containing
                     protein"
                     /protein_id="HDF3911695.1"
                     /translation="MKSQKRFKILDIDVYLQPFESDIKKRMKHYEDMKSKTLKNYKDF
                     SSFANAHLYYGFHQTNDGFFYREWAPNADSLSLIGDFNNWNRKSHPLRKIGSGNWEIF
                     IPGQNSLPHKSEVKVQVTANGKTFDRIPLYIKRVIQKDFGGFNGQIWQPKTPFIWTDN
                     DFDLKNITSPLIYECHIGMSTESESIGTYNEFTEKILPKIKKAGYNTIQLMAIMEHPY
                     YASFGYQVSNFYAISSRFGTPEDLKNLINTAHSMGIAVLLDLVHSHAVKNTLEGINEF
                     DGSEHQFFHSGSKGNHPAWGTKLFNYGKPEVIHFLLSNIKFWLNEYHFDGFRFDGVTS
                     MLYHNHGLGVSFDSYEKYFSMNTDIEAITYLQFANELMKEIKPNSISIAEDMSGMPGM
                     CIPIKDGGIGFDYRLAMGVPDFWIKTISNLSDEDWDLGKMWYELTTRRPGEKNIGYCE
                     SHDQALVGDKTIIFWLADKEMYWNMEINSNNHVINRAISLIKLIKLITFSLAGEGYLN
                     FMGNEFGHPEWIDFPREGNNWSYKYARRQWSLSEDNNLKYKQLLNFDKSMLELTKYSD
                     IFIQNSHELIHMDNDKKILVYSKGKYLFIFNFHPNLIQSVDISKFQNTNYKTILNTDM
                     VEFGGNTKKENLRDYDVYFSSTPPSSKMPIASRTAIVLLDNGI"
     gene            complement(43282..43920)
                     /gene="recX"
                     /locus_tag="PC494_001176"
     CDS             complement(43282..43920)
                     /gene="recX"
                     /locus_tag="PC494_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HDF3911696.1"
                     /translation="MGIITKIEQQKRNDDRVNIYVDDKFFIAIFKELVYTFNLKKGNE
                     INEEELKPILDDEMYIKAKNKALNILSHADQSEKKLKEKLSSEFDENIIERVIDFLKS
                     YNLVNDSVLAQKIVNTNVNLNKCGKNRIKQNLYNKGINRSTINEAVSELDKDTEFENA
                     MYLAKKRYERVKKEDKKKIYQKISQHLSYKGFDYDIIKRVLNKLLNFDEYDI"
     gene            44196..44885
                     /locus_tag="PC494_001177"
     CDS             44196..44885
                     /locus_tag="PC494_001177"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HDF3911697.1"
                     /translation="MRSENLVKMAELKNTEKLEKFNRHKGKIKIGILGGTFDPIHYAH
                     LATAEFIRDKYDIDKIIFIPSGNPPHKLCITTDKYDRYNMTLLATESNEDFLVSKVEI
                     ERKKRTYTIDTLKYLKKKYKNADIYFITGADAICSVEEWKDVKKNFELATFIAATRPG
                     ISLLRSQETIEKLTKKYNADIITVYVPSLDISSTYIREQLNEGKSIRYLVPENVENYL
                     YENKLYQYGDD"
     gene            44886..45458
                     /gene="yqeK"
                     /locus_tag="PC494_001178"
     CDS             44886..45458
                     /gene="yqeK"
                     /locus_tag="PC494_001178"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HDF3911698.1"
                     /translation="MNLENINQRLNQMLPVGRLSHSKNVAKCAEKLCEIYGCDKEKAY
                     LAGMIHDCAKYLSDKEIEDYVNKYEIYLDPIEDGNRSLSHSVIGAYICEYEFEVEDED
                     IINAIKYHTTGREDMSLLEKIIYIADLIEEGRKFPVVDTLRELAYGGKLDEALLTSFN
                     NTLMFVINKKEEIHPRTVMARNYLIKEKLL"
     gene            45575..45925
                     /gene="rsfS"
                     /locus_tag="PC494_001179"
     CDS             45575..45925
                     /gene="rsfS"
                     /locus_tag="PC494_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HDF3911699.1"
                     /translation="MTVEQMTKIAYDAIEDKLGQDTVIINIGKVSSLCDYFIITTASS
                     QRQVKAIADNVEDELAKLGLEPRGKEGQGTQTWVLLDYGDIMVHVFNEENRGFYNLEK
                     LWKDAPYIDIDTLA"
     gene            46279..48699
                     /locus_tag="PC494_001180"
     CDS             46279..48699
                     /locus_tag="PC494_001180"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HDF3911700.1"
                     /translation="MSVYNFKEVESKWQKIWKDNNQYKMDTAQTEKPNYYTLEMFPYP
                     SGKIHMGHVRNYSIGDVVARFKKMEGYNVLHPMGWDSFGLPAENAAIKHGIHPHKWTM
                     ENIEEMKEQLNLLGISYDWDKEVATSTPEYYRFTQEIFLKFLEHGLAYKKKSYVNWCP
                     SCETVLANEQVVQGACERCKATVLKKDLEQWYFKTTEFAEELLNDLDILDGWPEKVKT
                     MQKNWIGKSTGADLVFDIDGTDKSMTVFTTRPDTTYGVTYMVLAPEHELVKELVAGTE
                     YEADVEAFVQKMHTMTEIERTAADVEKEGMFIGRYVINPLNGKKVPLWIANYVLVEYG
                     TGAIMAVPAHDERDRDFAEKYNLDIIDVITEDNKMINSEEFNGLDASEGFEGIIDKLE
                     KEGRGKRTINYRLRDWLVSRQRYWGCPIPVVYCDECGIVPVKKEDLPVLLPTDVEFTG
                     KGESPLTTSKQFMSTTCPHCGKPARREVDTMDTFVDSSWYFLRYVDSNNENEPFSKEL
                     VNRWHPVDQYIGGVEHAIMHLLYARWFVKAFKSMGMVDFNEPFKNLLTQGMVLMDGSK
                     MSKSKGNTVSPMDIIDEYGADTARLFVLFAAPPERDLDWSEQGVDGCFRFLNRVYRLV
                     DELADVVKKDVEFGELNSQDKDMRYTIHSTLKKVTADLSEKFGFNTAISALMELINDM
                     YKYKELDNINEAVIKEGVQTIVTIIAPFAPHLGEELWTMIGKEGSVFDIDWPKYDEKA
                     LVKDEIEVVVQVNGKVRGKLTVNSNISKDEMEKVALEDEKIKGLVEGKTIVKVVAVPK
                     KLVNIVVK"
     gene            49552..50220
                     /locus_tag="PC494_001181"
     CDS             49552..50220
                     /locus_tag="PC494_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HDF3911701.1"
                     /translation="METVTNNQSGVEIQLSLFEAIKDLLLINPIFLLGIILIGIFLVV
                     IFKKNSDIPKVKTSILSLAMYYYLCLTLSHIVGIPTFSEYIRLSQLGETFFNPNINLI
                     PFSDGFSLSFILNILLFVPLGFLCPLISKTFERLRNTFLIGFGLSLFIETIQLFTLHR
                     ATDIDDLLTNVIGTIIGYFCFKLIAKLRIVKLHSDDDSMEQDYTVCIPIAIIIVALIL
                     GFFS"
     gene            50260..50340
                     /locus_tag="PC494_001182"
                     /pseudo
     CDS             50260..50340
                     /locus_tag="PC494_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005541856.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
     gene            complement(50703..51820)
                     /locus_tag="PC494_001183"
                     /pseudo
     CDS             complement(50703..51820)
                     /locus_tag="PC494_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861579.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
     gene            52036..53406
                     /locus_tag="PC494_001184"
     CDS             52036..53406
                     /locus_tag="PC494_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp29"
                     /protein_id="HDF3911702.1"
                     /translation="MKLKKLLSLGLVSMFVAGFPISANALDKIDKIQGADKYETAGII
                     ADKQSYTTAILINADSTMADGLSASGLAGATNAPILLTKKNNIPNATLKRVEKAKKVY
                     IIGGESSIDKATETFLKDKGIETRRLQGNDRIKTSYNVAKEINSINKVNKVILTNAFK
                     GEPDAMSAAPVAVRDKAAIVLTDGKSVPFNTTGIESYAIGGTSSMSDSLVNDTNSTRL
                     GGVDRYDTNKKIVNKFYNGAKEFYIASGTDLVYALVASPMAKNNPIVLVDIGSNKDIL
                     KNAAKVTGIGNLSDKIMLECENTINNISLPSSNKNIICGLKIDFDSNHIIWQDKGSYL
                     ECYDDNLEYYTEKYKDPTVPINIENTSTQNLDVTKLKVYGEANSTLYMGQYAKIKMDF
                     NSFGVLKPGEKCTIYLDIISLDPSRSMTLTFSYVGDKENYKYEQGLASRILFYNPDGE
                     DFFEYK"
     gene            53700..53858
                     /locus_tag="PC494_001185"
     CDS             53700..53858
                     /locus_tag="PC494_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3911703.1"
                     /translation="MDNFLQGILASLSASLIVYIASKLFRKRKKPLKAATKSGWEFDL
                     KIRFHKTK"
     repeat_region   54144..54702
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=54144..54173
                     /rpt_unit_seq="gttttatattaactatatggaatgtaaatt"
     regulatory      complement(54843..54940)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            55167..55550
                     /locus_tag="PC494_001186"
                     /pseudo
     CDS             55167..55550
                     /locus_tag="PC494_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431032.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
     gene            complement(55728..56723)
                     /locus_tag="PC494_001187"
     CDS             complement(55728..56723)
                     /locus_tag="PC494_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HDF3911704.1"
                     /translation="MSIKKKVAIVFTGGTISMTVDDKVGAAIPTLSGEQILSMVTNID
                     KVADVEVFNFDEIPGPHITPYRMMELKNYVNDLLARKDITGVVITHGTDSLEETAYFL
                     DLTIDNIKPVIVTGAMRSSSELGYDGSSNLSASVCTAVSKDAMGKGVLVVLNNEVLLA
                     SEATKTNTLSLNTFKSLTSGPLGIIDCNELVLTRDIVNRTIIDTDKVESKVALFKAYV
                     GENADFIRFAVDSGYKGIVIEAMGRGNIPPQMLSGVEYAREKGLPVVIVSRCHSGRVF
                     DSYGYFGSGRDLKNLGCIFGGDLPGQKARIKLILALGKTDNLDEIKDFFEKGIYC"
     gene            complement(56844..58472)
                     /gene="aspD"
                     /locus_tag="PC494_001188"
     CDS             complement(56844..58472)
                     /gene="aspD"
                     /locus_tag="PC494_001188"
                     /EC_number="4.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate 4-decarboxylase"
                     /protein_id="HDF3911705.1"
                     /translation="MKNHTYKEIKNIYGKISPFEFKDKLIDIAKYTAKENNRELLDAG
                     RGNPNWTCSTAREAFFTFGHFAITETRSNWDLGHLAGMPQKKGIKERFFKFINENIDM
                     PGAYLARDIINFGINELGFDGDEFVHELADGIIGDNYPLPDRMLPHMEKIVHDYLVQE
                     MKYDISGKYGDVEIFAVEGATAAMCYIFDSLMANELLKKGDTIALMTPIFTPYLEIPN
                     LPRYDFKVVNINANEVDEKGAHTWQYTKKELEKLRDKSIKALFVVNPNNPASIAMDET
                     SCNNLIDVIENYNKDLMIISDDVYGTFVEDFSSLMSKLPYNTVGVYSYSKYFGVTGWR
                     LGTFALHKKNVFDKKINDLTGELKKSVDKRYSDMSLNPSSLSFMERVVADSRLVALNH
                     TAGLSTPQQVQMAFFSAFALIDKVDAYKKLNMSICHRRQKLLFEALELPINENKNNAA
                     YYTQFDIEEWAKLNYGEDLFKFISKTASPVDVLYKLANDYSVVLLSGNGFYGPEWSIR
                     ISLANLYDEAYTKIGKAIREILNGYIVEWQKIKK"
BASE COUNT        22606 a         6665 c         9947 g        19444 t
ORIGIN      
        1 atccaaaaac ttttctaggt ttaaattata ccatatttat agtatgatat gattataatt
       61 ttatataata aataagtaaa aatagtaaaa aataaattaa gaaatgtttt taataaaaat
      121 aagcttaagg gggtcaacca tgagtgcaaa ggtaacgaat caatatggaa atatagaaat
      181 agataatcaa gtaatagctc aagtcgtata tagagctgca atggaaagtt atggcttagt
      241 aggtttagca tataagtcta aaggaatagt agagctatta aaaggcgaga acgcaactaa
      301 aggtgtaaga gttgaggaag tagaagaaga tgccatagca atcgaacttt atgttataat
      361 acaatatggt acaaatatat ctactgttgc caataatata atagatagag taaaatatgt
      421 agttgaaaaa atgactggcg taagagttac tagaattgat attaatgtac aaggaataag
      481 agttaagtaa tttcatagga ggaaacaaat gattcaatat atagatggta aaaggttaag
      541 ggagatgttt atttcaggtg caaacaatct ccaaaacaat aaagagttag ttgacaagtt
      601 aaatgtattc cctgtaccag atggagatac aggaactaat atgtcattaa caatatctta
      661 tgccttaaaa gaattagcaa aagttgaaaa tgataatata tcagatatcg gaaaagcatt
      721 atctaaaggt tctttaatgg gagctagagg aaactcagga gttatacttt cacaaataat
      781 cagaggtata gctaaatcta tagaaggaaa aagtaaatta tcaacagaag atttagcaaa
      841 agcttttaaa aatggttcag acacagcata taaagctgta ataaaaccaa ttgaaggaac
      901 tatacttact gtagttagag aaagtggaga gtttgcaata aaaactgcga aaaaagagaa
      961 agatgtagta aagtttttaa gtatgcttgt gaaggaatca aattcttcat tagaaagaac
     1021 tccagacctt ctaaagaatc taaaagaagc tggtgtggtt gactctggtg gaaagggtct
     1081 tgtacttata tatgaaggaa tgttagcttc tataaaaggc gataacatag aaataaaaaa
     1141 tgttgaccta gatactaata tttcaacaag tatggatttt gcaaagagta ctactagcac
     1201 agatgatata aaatattgct attgtacaga atttatttta gaaagttcta aggtagaaga
     1261 tactaaaata agagacataa tgatggctta tggtgatagc ctagcagtag ttggagatga
     1321 tggagtcata aaggtacatg tacacactaa tgacccagga aatgtacttc aagaagctct
     1381 aaagtacggt caattattaa ctataaaaat agaaaatatg aagttacaac atgaaaatac
     1441 attactggat gtagaagaaa agaaagaaaa tgatagtgaa cctttagaag aagaaaaaga
     1501 gtttgggttt atagctactt ctatgggtga aggtttggca aatatattta aagatttcgg
     1561 agttgaccat ataatagaag gtggtcaaac tatgaatcca agtactgaag attttatgaa
     1621 tgctataaag catataaatg ctaaaaatat atttattttc ccaaataaca gcaatataat
     1681 aatggctgct aatcaggcaa aagaattgag tgataaaaat ataatagtta tacctacaaa
     1741 aaatacgcct caaggatttg ctgcattagt aacttttaat ggagaattaa gcgaagatga
     1801 aaataaagaa gctatgatga atgctttaaa ctcagttaaa tcaggtcaag taacttttgc
     1861 tgttagggat acagtgatga atgaaattga tgttaaagaa ggtaatataa ttggaattgc
     1921 agaaggaaat ttattatcag caggagatta tgtggatgaa gtaacatcaa accttattga
     1981 aaagttggtt gatgaagata ctgctataat aacattattc tttggtgaag atgttacaga
     2041 atctcaagca aatgaactac gtacttcttt agaagaaaag tttgaagatg tagatgtaga
     2101 gttatattat ggaggacaac ctctttatta ttacttaatt tcagttgaat aatgattata
     2161 agaacctgta tgaccaagta gcttttataa aattggttgt acaggatttt tgtgtagtag
     2221 gtgatatatt tgttggattt atataaagat gttcaatatg ttaagggaat aggacctaaa
     2281 aaagcagata aattaaataa actgggtata tttacactaa aagacctatt gtattatttt
     2341 ccaagacaat ttgaagatag aaataatcta aagaaaatag cacaattaga agatggtgag
     2401 aaagttacga taaaagcagt aatatcaagt ataaatacat ttagcccaaa agaaggtatg
     2461 actttaacaa agattgatgt aaaagatgag acaggctcgg ctaaattagt gttttttaat
     2521 aagagttata taaaaaatac ttttcgtcca ggagattcaa tattagtttt tgggaaggtt
     2581 aagaaaaaat ttaataactt agaacttaca tcatgtgaat tagaatatct tactaattca
     2641 cctaagaata catgtagatt tatgcctgtg taccagctta catacggtgt tacaaataaa
     2701 gaaattatga gtataattag aacagtactt gaagataaag aattaattat acaagaatat
     2761 atgccacaaa gaattataga aaaatatagg ctatgtagta tagattttgc agttagaaac
     2821 atacattcac caagtagtaa ggaatcatta aaaatagctt tatatagaat tgtatttgaa
     2881 gaattactta tactacaact agggttgttt gtatttaaaa gtggcagaaa taaagaagat
     2941 ggaataaagt ttgaaacaag taaagactta aaaaaaataa taagtgcttt accatttaaa
     3001 ctgactaaag ctcaaaacag ggcattagat gaaattatac aagatatgaa tttagagaaa
     3061 ataatgaata gattggtaca aggtgatgta gggagtggta aaacagtagt agctctctta
     3121 gcacttgcaa attgtgtttt aaatggttat cagggcgctt tgatggcacc tacagagata
     3181 ttagcagggc aacattatat ttcacttact gagtctctaa aagattttgg aataaatgta
     3241 ggtctattaa taggtagtct tacaaaaaaa caaaaggata cagtattgga acaaataaag
     3301 aataatgaga ttgatatatt aataggtaca catgcactaa ttgaagataa ggttgaattt
     3361 aataatattg gtttagttat aacagatgaa caacatagat ttggtgttat gcaaaggagc
     3421 aaactttcat tgaaaggagc aaatcctgat atattagtaa tgacagcaac accaatacca
     3481 agaactttag cacttatact ctatggagat ttagatattt ctattataga tgaacttcct
     3541 ccaggaagac agccaataga aacaattgct attgaaaaaa gtaagcgaga tagagcatat
     3601 aataatcttg taagaagaga ggttgaatca ggaagacaag tgtacattgt atgtcccttg
     3661 gtagaagaaa gtgaagccat agaagccaaa tcagcagttg aacttgttga ggagttaaga
     3721 gcggaatatt ttcacgactt aaggcttggg ttgcttcatg gtaaaatgaa gtcaagtgaa
     3781 aaagatgaag taatgagact ttttaaagat aaagaaatag atattttagt ttcaacaaca
     3841 gtaatagaag ttggtgtcaa tgtgccaaat gcaacattaa tgataataga aaatgcagaa
     3901 agatttggac ttgcacaatt acatcagctt agagggcgag ttggaagagg tagtcataaa
     3961 tcgtattgtg tactaattta tgattctaaa acagatgtat gtagacaaag aatggctata
     4021 atggaagaga ccaatgatgg ttttaagatt tcagagaagg atttagaaat aagaggacct
     4081 ggggaatttt ttgggacaag gcagcatggt cttccagaac ttaaggtagc aaacttattt
     4141 aagcatataa aaatactgaa gttagcacag caagaagctc gatatatatt gggtgaagat
     4201 aataatctac aattaaaaga aaacatggca ctcaaaaaag aaattataga taaatttaaa
     4261 gatacattga aagaaatttc attaaattaa ttttaaattg tgttaaaata ttactaatgt
     4321 aataatgtgc tgaagggaga ttgtcatatt gagagtaatt tcaggaaaag cgagaggatt
     4381 aaaactaaat actccaaaaa atgaagatgt aaggccaact acagatagag taaaagagtc
     4441 tctatttaat atgataaatt catatataat ggaaagtgaa gttctggatt tatttgctgg
     4501 gactggttct ttaggaatag agtgcttatc taggggtgcc aagtcatgta cttttgtaga
     4561 tattagtaag gaaagcatag atattgttaa gtccaatata aaaaaggcaa gagttgaaag
     4621 tgaaagtatt attttaaacc ttgattttaa gactgcaata gataaactta aattacaaaa
     4681 tagtaaattt gacataattt ttatggaccc tccgtattat aaaaatatgt ttatagaagc
     4741 tattgaaaaa attgataatt ctaatctatt gaacgaagat ggaataatag ttgtagaaca
     4801 tgatacgaat gatttatttc cagataagat atgtaaattg gagaaaacta gagataagaa
     4861 atatggaaat actacattaa ctttttataa gatggaggca taatatggaa aataaaccta
     4921 gaaaagctat atttgcagga agttttgacc caattactaa tggacattta gatattattt
     4981 gcagggcttc gaagttattt gacgaattac aaataggagt attaaataat cctaataaaa
     5041 agggtctatt tagctttgat gaaagagtaa aacttataga aaaaagtaca agccatttaa
     5101 ataatataaa agttgtgact tttgatggtt tattaataaa ttactgtcag gaaaatggga
     5161 ttggagcatt agttagaggt gtgagaagtg gtgctgatgt tgattatgaa cttcagatgg
     5221 cacatatgaa tagagagctt aatccagata tagagactat aattttacca agttgtacaa
     5281 aatattcatt tataagttca tctttaataa aagaggtttt gctctttgat gctgatataa
     5341 aaaatttggt tccaaagatt gttttggaag aattaaagaa aaaaactagt gggggtaatt
     5401 gatatatgaa gatagattta gaaatgattg aactatttga gcagttagag gagatattta
     5461 gaagtgcttc tacaatccct ttctcacata aatgcacagt ggataaagat gaggttttag
     5521 caataattaa tgatataaga actttaatac cagaagaagt aacacaggca gtatggatta
     5581 ataaagaaag aaataaaata ataagtcaag ctaagcaaga tgctacaaat atagttgaac
     5641 aagcgaaaaa agaagctgag agaatacaac aagaatatca agataatata gaggaattaa
     5701 agaaaaattc tgaagatgta gtaaaggcat atgtagaatc cagtgaacct gttgttcaag
     5761 cagaccaaag agcaaaagat atagttgata gagctgagag aatagccaat gagataagaa
     5821 ttgggtcaat tgaatatgca gaggatgtgc tttctagtgt tgagtataat ttaagagaaa
     5881 tattagaaga agtaaaaaga gataaagctg aacttagacc taaaaaataa attttaaata
     5941 aataaaaatg gagctatcac acaaaaaatt ccaatttatg tgtgatagct ctcttttaat
     6001 atagcaattt tttgttatat aattgtgctt tttagattac ttatatctta ttttgatatt
     6061 ataatgtagt ttaatctttt atttgttgaa atcaacttat ttatttgtat aaataatata
     6121 ggttattttc aaattttttt aataatttta ccactgtctt cttttagatt agagttagac
     6181 tgtgcaaaat tataaaataa tactaaatca tgtgcaatta tttggtatgg cactacatgt
     6241 agaaaatata gataataaaa ttaaggaggt agtatgaagg aaagggctaa aaaaatatta
     6301 gattttatta ttaaaaataa caatgtaaca tcacaagaac tacaagaaaa gtttaatgtt
     6361 tcaaagagaa ctatttatta cgatattcta gctataaatg aacaactagg aaaaagtggt
     6421 aatataaaaa atgtaaaaca caaatttata tttgaaggta atttatgtga tgcaaggaaa
     6481 ataatttcaa ctgaagaaga taaattttta gatagtgatt acagaaaaac ttttatatta
     6541 aacaagatat tacttggcga aaaaatatca atagaaaaac taacaaatga aatgttactt
     6601 tcaaaaaaca cagtagtaca aacaataact gatgtaaaaa aataccttca aacaatgggg
     6661 ttaagattag agtataaggg aaagtacaaa attataggtg atgaatacgt tattagagag
     6721 ctgtttctga taattgttca agaaaatata ttggaaatta attctataag tgaggaagta
     6781 agtagtttcg atacaaaagg acatataaaa cttactgatt attctttatt aaatctaact
     6841 aagtttgtgg aatttctaaa taaaaggata agagatggga aaacattata ctcatataaa
     6901 tatctaaatg aagctaaaaa aattagttac tttagtaatt gtaaagaact tttatgtgaa
     6961 gaagctaatg aaaatgaaca agcctatata tgcacttaca taagttcact tcccagctta
     7021 aatagtgaag ttaaggaaga tgttgttgaa gaatatgtag ataaacttat agataagttt
     7081 gaagtaaata cagcaataaa attagaaagt aagcatgagt ttaagaaaaa tattttaagg
     7141 cacctccatt cttcttacaa cagaatacga tttaagtttc ctattagaaa tccaatgtta
     7201 gatgagacta agtataaaca tgagtcactt tataaaatta taaaatcaat tatagaaaat
     7261 gaagaagagt ttcctgtatt tgaggggata agagaagaag aaataggatt tatagcagcg
     7321 tattttggag gatatttaag agggtctagg gataatggtc taagaagaaa taaagtctta
     7381 ctagtttgtc ctaatggtct tatggtatca aagagtttgg aaatacaact atataaatac
     7441 ataccaacca tagaaatagt aggtatagta tccattaagc aactaaaaga agtaaatgta
     7501 tactacgatt acataattac aactatagat atacaaaatg taaacaacgt aattgttgta
     7561 aatcctcttt taacatcatc agatgttcaa ttacttatga acaaactaat aagtgtaaaa
     7621 gaaaacgaga agtatttcaa tcttgaatta ataatacaag ctataagaaa aaatggagtt
     7681 atcaataatg aagaagcact aaaagctgat ttattaaaca taatacacaa gatagatgaa
     7741 ggagagatgt atcaaccaat gttaaaggaa ttaattaatg cagaaagggt caatataata
     7801 aaaagtgtta gagattggaa agaagcaata aaaatagcct caaagccatt gttagaagat
     7861 aactctatag aagagttata tatagaaaat atgataaagt cagttgagaa atatggacca
     7921 tatattgttt tagctgatag atttgctcta ccacatgcaa gttctaaaga aggagtaaac
     7981 aagcttgcta tgtctttact aatagtagaa gatgaagttg atttattagg aaaaccagta
     8041 aatatattta tggtattagc tgctgtagat aacactactc acattagagc attagcatca
     8101 ctatcagaga tgatgtacga ggaagaaaat gtaaaactaa taattaatgg tgataaaagt
     8161 tcaatactag aacttataaa taagcaaaat taggaggaat gaaaaatgaa gatattagca
     8221 gtatgtggtt ttggtgtagg ttcatcaatg gtattaaaaa tgacaataca aaaggctcta
     8281 aagcagttag gtatagaatg tgaagtagaa aatacagata taaattcagc tagaggtgct
     8341 gattgtgact gtatattcac aagtcaagaa ttgttaaatg aattaaaagg aacttgtaat
     8401 gtagatgtat atccagttaa aaagtacatg gatttagcag aagtcacaga agttgttcaa
     8461 acttttttaa gtgataaaaa tgataagaaa tagtataagt tttaaaaagt aaatttaagt
     8521 taatcagaat aaaataaaaa cttactaaat tcaaaaatag taagaaagag aggagggatt
     8581 tagtggtaga aaacttaaac agttgaccta tcactaaaaa atataatgct tgattttatt
     8641 tcaaataata ttttacgtaa tccatctatg ttaattggat taatagcagc atttggtctt
     8701 gtactacaga agaagaaagc atctgatgtt ataaaggggt cactacttgc agctttcgga
     8761 attataatta tggagactgg aacaggtatg ttagttagtt caatagcacc aattaatgga
     8821 gctttccaaa gtataagtgg tggtgcagta acaaaaggtt taagtgatgt tacttttact
     8881 gcaagttatg gtggaattat aggtttagca atgtttgcgg gtttagctat tcacctaatg
     8941 atagcaagat ttactcctat taagacaatc tttttaacag gtcacatgct ttattggttc
     9001 ccattcatat ttgtagcttc aggagttgaa gctggattaa atggtggagt attaatagct
     9061 tttgcagcag tattatcagc actctattgg tcaataatgc cttggttatt aagaaaatat
     9121 gtgtttgatg ttataggaga tgattctttt acattaggtc atccatctgg ttgtttagca
     9181 cttatatcag gatttgttgc taaattagta ggaaataaag aaaaatctac agaagatata
     9241 aacatacctc aaagtttatc attttttaga gaaatatcta taagtggtgg aatggcagtg
     9301 tttttaatgt ttatagttgt tgggatagta ataccaggtg cgtttaaaga tagtaatgag
     9361 tttattggaa cgtatgcaat aaagcaaggt ctttcttttg gagcaggtct tataataatg
     9421 cttcatgggg taagaatgct aataaatcaa ataatgccag catttcaagg tatatctgaa
     9481 aaagttgtgc caaatgcact acctgctttt gactgtccaa tattatttaa ttataaacca
     9541 aatgctgtat taatgggatt cttagttgct atgctaacat ctacagctat gattttaata
     9601 tgtaactact ttaatgtatt taatttgcta cttataccac ttgttataac ttcattcttt
     9661 gagtgtggag cagcagcagt aataggagaa tcacaaggtg gtatacgtgg agctataata
     9721 ggtacagcta tagctgcaat atttatggta gttttagtag gaatatctgc tgtaatttac
     9781 tcaggaacta ttcaaaattg gatactaata tttggaggta atgacctttc attatttggt
     9841 ataatcagta ggtttatagg ttcactattt ggaggaatat tatagatatg aaatttaaat
     9901 acatagatga gataagaaga ttaattgata taatagaaaa cgaagaaaaa gtcaatatgg
     9961 aaaaagcagt acaaatcttt gttgaagcaa tagaaagtaa aaatgctata ttttcatttg
    10021 gagcttcaca tgcaggaata ttaacagaag aattattcta tagagcaggt ggctgtgttc
    10081 ttataaatcc agtatttgca aaatctctaa tgttagatac agcgcctata actcacacaa
    10141 gtaagatgga aagattagaa ggatatggta cagctctagc tgataaaact ccaattaaaa
    10201 aaggagatgt agttatagtt cattcagtat ctggtagaaa tccagtaagt atagagtttg
    10261 ctatgaaagc taaggaaaat aaggcaatag taatatgtat aactaattta agttactcaa
    10321 aaagtgtatc ttcaagacat tcttcaggaa aaaaacttta tgaagtatgc gatttagtga
    10381 tagataatca tggtcaaaag ggagatgcct gtgtagagat agatggatta aaccaaaaag
    10441 ttagtccaac ttctactgta atagcaacta ctgtgatgaa ctctattata gctcaagcta
    10501 ctcaggaatt agttaataaa gggctaaaga atcctccgat tttctatagt gcaaatattg
    10561 atggtggaga tgagttaaat aagaagattt ttgatgaata taaaagtgta attcattatg
    10621 aatattaagg ttaaaaaaat atgttaatga actttgaagt ttatcaacaa agaatattaa
    10681 taatatataa taaatgctat catttaaaag ctgtaggtaa aaatctacag ctttttatta
    10741 ttgtagatta aaaagatgcg taattaaatt ttaaattgga gaaaataaat tggaaggtat
    10801 caattataaa tattagaaac gttgtcatag aaaaaaacta tattaaaaaa aagtacatag
    10861 aaaaaactga ttagacaata aatacatgct ttgataatat tttaaatgga gtgaaaatgt
    10921 gtagaattat aatgaaaaaa gaaaataaaa atgaaaaaag aaaataaaat ggagggaata
    10981 aaagtgggta tgttaaaaaa attatgttca ctagctatgg tagcaattat gactacaaca
    11041 cttataacag ggtgttcaag tggaaatgga aaagattcaa aaaaggatgg cgaaaaagaa
    11101 aaactagttc tttggatgcc accagtagaa aataatatga aggaagtttg ggaccctatt
    11161 ttagataaat ttgaggaaaa aaataactgt gaagtagatt tacagataat tccttgggat
    11221 aattattctg aaaaatttgc aacagctata agtgctggcg aaggtccaga tgtaggatat
    11281 atgtatgcag aaatgtatcc acagtttata gaaagtggag cagtagaaga tttgactaat
    11341 tatgcaacta aagaggataa agagcaatct atttatataa aaacatctga aatgatgggt
    11401 ggaatgtatg gtatgccatt ccaagcagca aatccagggg tattatacta taacaaggat
    11461 attttagaga aattaggaga aaaacctcct aaaacatggg aagattttaa aagaatttgt
    11521 aaaaaagcaa cacaagatac tgatggtgat ggaaagatag accaatgggg attagctcag
    11581 ggatggggag ctaaaacttt tggtaactta aactggaact ggtatcctta tttatggcaa
    11641 gctggtggag atatctttaa tgatgattta aaatcggtta aatttaatga taagagtggt
    11701 ttagaagcag ctaatttctt aaaagaatta caagcatatg tgcctgaaga ttctttatct
    11761 aaagatagta atgaaatgat agaaagtgta tttggaccag ggaaagcagc atttacaata
    11821 atgttatctt ctgctgcaac aagtgtattt gatgaatcat tcccggattt aaattgggga
    11881 tttgtaactg gactagaaga taagaaagca gcaacttttg gagcagtaga ccatttatct
    11941 ttaatgtcat ctgctaaaaa taaagaactt gcatacaagt taatacaaca tatgttaagt
    12001 gttgaatcaa tgacagaatt tcataaagca ataccaagag caccaataac aaaaggtgaa
    12061 ccatatcaag gtgatgaaag attcaaagaa atggtggaaa atgacaaaaa tgtatataga
    12121 ccattagtag taggacctca tggagttgaa atatatgaat atttatggaa agaacttcaa
    12181 actatgattt caggagataa aactccaaaa caagcgttag atgatgctgc aaaatattca
    12241 aatgatttat tagcacaata aaagtttaaa gctgtaatat gttgtaaagg actttacaga
    12301 ttaaaattag cattgtattt ataaatacaa tgctaatatt tatattggag aggataaaat
    12361 ggaaaactta gttagagagt ttgaagaaaa ttcaaaaaga aaaaaaacaa aattaaatat
    12421 taaaccatat atgtatatat tgccattggg aataatttta gtggcgtttt atgtgatacc
    12481 aataataatg tcaatatact ttagttttac aaagtataat attattagtc cagctacttt
    12541 tataggttta gaaaattata aaaaattatt tacagatgaa acattaaaag tatctattat
    12601 aaatactatt aaatttactg ttgttgtagt accttgccaa actatattat cattgatttt
    12661 ggctgtttgg attacaggaa aaggaaatag taaaatagct tcatttgcta aaggtgctat
    12721 atttatacca gtattatcat ctatggtttt gataggtatg gtatggaggg ctttattgaa
    12781 tggagaaggt tctattatat atcaggtatt aggtgccttt ggaatagaat catctaaact
    12841 tttaggagat agtaagacag cattacctac acttatgttt atatctatgt ggaaaaatat
    12901 agggtatttc atggtaattt atatttcagc tataatgaat ttaccaaaac actgctatga
    12961 agtagcgaag gttgatgggg ctacaaaact tcaagaattt ataaaaataa ctgtaccttt
    13021 attgaaacca actacaataa tggttgtatt tttagggtcg atatggtcat tacaagtatt
    13081 tgacttaatt tatactgtga caggtggagg tccaggtata tctactatga gtatagttat
    13141 gcatgcattt aacttaaact ttaaaaactt taattctgga tatgcaatga ctgtagcaaa
    13201 cgtattattt ttgttaatag cagtagtttc gattttacaa aataagcttg taagacgaga
    13261 caattcagat ttttagaaag gtaggtataa tatgaaaaca gcaagaagat tattaagtga
    13321 tggtttactt ttatttatag cgtgtgcaag tttggtacct tttatataca tgttgataat
    13381 atcattgaag ataacatata actcatatag tttggatata tctttttcaa cagtaaccct
    13441 tcaaaactat atagatattt ttactaaaaa aggatttgca caatattttt ttaatacagc
    13501 aatagtatct ttttcaggtg tattattaaa tttagtattt agtacattag caggatattc
    13561 ttttgcgaag atggatttta aaggtagtga taagttattt ttatttatga taatgacttt
    13621 aattatacct tcccaagtta caatgatacc actatatata ataatgaaac acttaggatg
    13681 gataaatagt tatcttgcac ttattatgcc aataccaact gcatttggcg tatttataat
    13741 gagacaagct attttaggag taccaaaaga gttattagaa tcagcaaaga tagatggttg
    13801 ctcggatttt agaattttaa tacaaatagt gttgccttta attaaaccag cattaattac
    13861 actagcaata tttactttta tgggagcatg gaacgagttt atgtggcctc ttatagctac
    13921 aactaaagat gcaatgagaa cattaacagt tggattatct actcttaaga cattccagat
    13981 aactaattat ggacagatga tggcaggggc tacaataaca tttttacctc catttatttt
    14041 ctatttgatt ttacagagta aatttgttga aggtgtgtct ttgtctggta taaaaggtta
    14101 aatagtctaa tttaataata tataaagaaa cttatataaa tatggaggaa tttaaactat
    14161 ggaaatttca tatgtactga aagattgcac attcaaacac aataaatact cagttgtaga
    14221 agctgaaact tggaaagata aggatttgga tattgtagta gctaaaggtg aaaaatttgc
    14281 atttcaaatt atgttaaaag caacagaaga atttaattgt acaattgata aaagtagtgc
    14341 tatatcatgg aaaggcctgg gaaatagagt aaggttagca ttaaatatgc ctaatagttt
    14401 agaaaataat tttagtataa atatattagg atatgttcaa gatgatacaa aggcatttgt
    14461 gaatgatgct attttaaggg ataaagatgt gttagtagag caatatttgc ctcaaacatt
    14521 ttggattgaa ggtcaagtac cagaagattt tgaagaaaat aaccttgata taggtattga
    14581 tatatttaaa agctttggat atgaagacga agaaaaagtt tgtacaattg atgttcctgt
    14641 aaaagtaaga aatgttgtgc taaagccttt agatgaaagc aagttctttt tagatttatg
    14701 gcaacatcca agctgtttag ctagaatgta taaagttgag ttatggtctg atatacattt
    14761 tgaaatagtc gataactatt taaaagaatt agcatcttta ggagaaaaag ttgcaacagt
    14821 tatagtttca gattatccat gggcagggca aagttgttat aaagtttata aaaatccatc
    14881 aaacttatat gaatataaca tggtaagtgt atcaaaagga ttggatggaa agattaaatg
    14941 taactttgag agtatggata ggtatataag catagctgat aagtataaaa tggctaagga
    15001 gatagattta tttggtctat taggtaattg gtgtgctggt gagtttggaa atcctgtaga
    15061 aggttataag gaccctataa gagtaagata ttttgatgaa aaggataaag tatttaaatt
    15121 tataaacaat acaaatgatt taaaagaata tataggatta gtattaaatc atttaataga
    15181 gtgtggatta tgggacagag taaggattat agctgatgaa ccaaataatc cagaagtagt
    15241 caaagaatgt atagaattta taaattctac tgtaggtact catcaagtta aatataaatc
    15301 agcaactcac gaccaaaact ttttagacag agctaaagat gaaattgatg atatgtcaat
    15361 aaatttaaaa cttactatac aaaattataa agatatagaa agtcttaaga aaaaaatcaa
    15421 tgacaagggt gggatattga cttggtttgt atgctgtttt ccagagaaac caaatagttt
    15481 tttaagttct ccttttgtag aaaatagaat aataggatgg tatacttatt actttggtct
    15541 tgatggattt ttaagatggg actataattt atggacagaa gacccttgga aagattcaag
    15601 ttacaaattc cctatttgga aagctggaga tatgttcttt gtttatcctg gaaaagattt
    15661 aaagccagtt agaagtgtca gaatggagaa tttaagattt ggaatacagg actttgagtt
    15721 atttacaatg ttagaaaaag aaaagggaag agagtatata gaagttgagc ttatgcaaga
    15781 attattaaat aaaaaagaaa atgctgaaat taaaggtttt ggtgacatag aactaggata
    15841 ttcacttgat aattggggat atgataaagt taaaaaatat gtattagagt tgttagacag
    15901 agtataaaaa atataagagt gtctcaaaat gaacttttta gttcatgagg cactcttttt
    15961 gtatgaaatc aatatagttt cattgtttca acaatgaaaa ataggattat ttctattcta
    16021 agacagccct ttagtttttt agttgtattc aatgttttaa aactaactat aaacgctata
    16081 aagtttataa atgacaataa ttatatataa catgatgtac tttaatttgc tataataggg
    16141 attgaataat attatatgga agataacatt gtttgggggg attaatataa aaagaatagg
    16201 tattattata atgttttttt taagtatatc ttttattgga ttttatcttg taataagaga
    16261 taacagtgat acagttaaga tgcaacgagg gataaatata ggtaatgcac tagaatcacc
    16321 taaggatttt ccgtgggatg taaaaatgtc aaataagttt tttgatgata taaaagatgc
    16381 aggttttgac acagtacgta taccagtaag gttttctgat tatacgtcag attctgataa
    16441 ttttaaaatt gatgaagaat tttttaaaaa gattgataaa tatgtagatt atgcattgga
    16501 taaagactta atagttgtgt tggatttaca ccattttgaa gaaattatga aagaaccaag
    16561 agttcataaa gaaaagtttt taaaaatatg gcaacagata gctaataggt atcaaaaata
    16621 tgataaaaaa ttggtatttg aattattaaa tgaacctaaa gaaaatttat attcacagtt
    16681 actaaacgaa tacattgaag aagcaataaa gataattaga aaaactaacc ctaaaagaac
    16741 tattatagta ggaccatata atttctatca aattgattat ttgaatgaat taaatattcc
    16801 taaagattct aatatagtag tttcctttca ctattacgag ccaaatgatt ttgcatttca
    16861 aggaaatata tatcataagg gatttgagca cttaagcaat attacttggg aaggaacaaa
    16921 cgaacaaatg gattatttaa aaaaaaggtt tgatactgtg gaaaattggg caaataaaaa
    16981 taaggtaaaa atcttcttgg gtgaatttgg aataacaaaa gaggcaccag aagcttcaag
    17041 aagagcatgg ataaaagctg taagagaaga agctgaaaaa cgaaactttt catgggctta
    17101 ttgggagctt gcatctggat ttggtatata caatcaaatt gaagggactt gggatagaga
    17161 tatattaagt gcattaatag aaaagaggtg attttatgaa gaaaaattca aaaaagatac
    17221 ttataacttt aactattatt actaatgtca tatatatatt gtggagaatt ttttacacag
    17281 tacctaaaga agaagggaag tttgccttaa tatgtgccat aatacttctt tttgtagaga
    17341 taatgggcat gatggaaatg tttgtgcatt attatggtat gtcaaatatt gagtaccctg
    17401 aaaaaccaat cataagtgaa gaactttatc cacatgtaga tgtattcatt gcaacatata
    17461 atgaatctgt tgatttggtg agaaaaactg taaatgggtg tattcatatg cagtatccag
    17521 ataagaaaaa ggtacatata tacatatgtg atgatggaaa tcgtgaagaa atgtgtattc
    17581 tagcagaaaa aatgggtgta aattacataa ctagaactga aagagaagga gcaaaagctg
    17641 gaaatttaaa taatgcaatg caacatacaa attccccttt gattgctaca tttgatgcag
    17701 atatgatacc aatgcatgac tttttaattg ctacagtacc atactttttg aaaaatgagc
    17761 aagctaaaaa agatggagaa aaagaggagt atgaaaaggt tggttttgtg caaactccac
    17821 agagttttta taatccagac ttgtttcaat ttaatctgca ctctgaagga aggattccaa
    17881 atgagcaaga ttatttttac agagacattc aattggctag aaataggaca aattctgtaa
    17941 tttatggtgg tagtaataca gttatttcaa gggaagcact tgaagaagtt gatggatttt
    18001 atacttattc tattacagaa gattttgcaa caggtatctt aattcaaagt aaggggtata
    18061 gatgttatgc tattccagaa gtacatgcat caggtttatc tcctacagat ttaaaaagtc
    18121 ttattaagca acgtgaaaga tgggcacgtg gatgtataca aactggtaga cgtctaaata
    18181 ttttgtttag gagaggttta ggtttttggc agaaaataag ttatatttct tcaattactt
    18241 attggtatgc aagtataaaa cgctttgtat atataatggc acctatttta ttttctgtgt
    18301 ttaatgtgat tgtagtaaaa tgtacgttac ttcaagtatt ggtattttgg ttgccaatgt
    18361 atattttaag tagtttatct cttaaaatat tttctcaaaa tataagaaat actagatgga
    18421 ccaatatata tgaaactata atgtttcagt ctttaatgcc agcagtaata cttgaaacgt
    18481 ttgcaatatc taaaaataaa ttttcagtaa caaataagag taaattagaa gaaaatagaa
    18541 tgtataagtt tttacaggga ataccttatt ttatttacat ggtcttatct atcataggaa
    18601 ttttaaaaat gtttgtagca atatttaaaa tgagttcaat gacatattca gttgtattat
    18661 tttggttgat tggaaacctt tttaaccttg ttatggctac attatttata tcagggagac
    18721 agcagttaag aaagtctgag cgttatattg ctgaaattga ttttaagtta aagcaaaatt
    18781 cttatgttct ttcttcaaaa acaattgata tatcagaaaa tgggtttgca tttttgctag
    18841 aaaatccaga atatatttcc ccagaagaag agtttgaggt agagtttaga gaaaaatctg
    18901 gaaatgaaat gtatatagct aatatgaaag caaagattgt taatgttgtg gaagtaaatt
    18961 caaagtggaa atatgcagct tatattacac atattgaaga tagtgaaata gataattgga
    19021 tgtgtattgt tcacgataga atacctactt taccaatgac aatatctaat caactaggtt
    19081 tctttgatga tttgcaaatt aatgtaaaaa aacgtattga aaaaactaga acattatcac
    19141 gaagaagtcc aagaatcaat atgaattttc agatggatat aaaaaataca ggtaaattaa
    19201 gaatagtgaa ttttaattat caatatgtat tattaaattt tgagaataaa agtatttatc
    19261 ctaaagaaat agcattggaa attaatgaaa atattgtgtt agaatgtgat ttgtgtgagg
    19321 gtaaaattga tgaaagaggt atcttatata aagtaaataa cattgacagc ataatgcaaa
    19381 atttcttttt aagagatgaa atgatggatt ggatattaca aaataagaaa attcttgatt
    19441 caaagcctag tgaaaagaag gaaaaaagta tagatgagtt tgaacccatg gaatatattt
    19501 aggagagatg aaatgaagac tttaaaagtg tttttttgtt ctacaaaata tcttattttg
    19561 gtgtttattt tttttataaa tactactttt ataagttcag caacaagtga taaaatttta
    19621 gatttatcct ttaaaaagat agagactgac ttaagttcta agattacata tgaggataca
    19681 ggtgtaaaaa tagaaacgga tagttctaaa agcgataagg aacgttattt atatatttac
    19741 caaaatataa aagaaaattg gagcatgtat aataattttt atattgaaat tcaaaataaa
    19801 aataaaagtt ctcagagaat aaatttaagc atacaaagta aaaatatgct tgaatttaga
    19861 ttaaaagaag gtagtgaagt atttttagaa ggtaaaaata taatatattc agataaaata
    19921 aaagaaggat gcatagaagt accaggtgaa tttgaaggca aaatttatgt gaactttaat
    19981 agccttataa atgaggaaag taatgttgtg ctggactcaa atatgctttc aaacattgtt
    20041 agttggggaa ttacgtttat tccatctgat gaagaacata atattgttat tataaaaaag
    20101 atatctttat tgtctgaaga gaaattaaga tttttaaata atattaaaat aattggcgat
    20161 gaagaagtac aaataccagt attgggtcaa agtataagtc agtatgaagt attaggtctt
    20221 aaaagtgatt ctaaaattaa gtactctctt atgggaaaac aagataatgt aagcatatct
    20281 caaaaaggta aattaacatt aagtaataaa gccaaacctg gacaaattat tttacaagtt
    20341 aatgttgatg ataagtttaa aattggaaag aaaataacat taactgagtc ttggagtgtt
    20401 aataaaaaag ataaggatgg tgttccatat acattagtat atcctgagca atcaccaaca
    20461 gtacaagata tgaaaaaaat aaactttatg aataacatca taacgtttgt tcgaatttta
    20521 tttgtatctc tagtaataat atgctttgga atatatttat attggaaaaa atgttcaaaa
    20581 actaagtaaa gagaggaggt tagattgtgt tattttcaag tttaattttt ttattttatt
    20641 ttttacctat aactttggtt ttatattatg tatttaggtt taaccgaacg atacagaaca
    20701 tgatattgct tgctgttagt ttattttttt atgcttgggg agagccaaaa tttgttgtta
    20761 tcatgatagt ttccataata atgaactata tatttggttt actggtagat agatataggg
    20821 aaagtaaaat aaaagtaaaa gtttttttag ttttgatgtg tgcatacaat ataggtgttt
    20881 tatttatatt taaatatcta gcttttgcgc taagaaatat tagtgaactt attagtactg
    20941 aattgactat acctagtatt gttttaccca taggaatttc attttttaca tttcagggaa
    21001 tgtcttatgt tatagatgta tatcgtagac atggagaagt ccaaaagaac cctttttatg
    21061 tgggattgta tatagcattt ttcccacaat taatagcagg tcctatagtt agatatgaga
    21121 gtgtggcaga acaaattctc aatagaaaag aaacttggaa taaattttct attgggactt
    21181 gtaggtttat aacaggtcta ggtaaaaaag tattaatttc aaataacatg gctatagtag
    21241 cagactatat ttacactatg aatagtcaag gagaaatagc tgcatcactt gcatggcttg
    21301 gttcaatagc ctatactctg caaatattct ttgatttttc tgcttattca gatatggcta
    21361 taggcttagg tcttatgttt ggttttaaat ttgaagagaa ctttaattat ccatatatat
    21421 caaaatcaat tagtgagttt tggagaagat ggcacatttc tttgggaatg tggtttaaga
    21481 gctatatata ctttccgctt ggaggttcta gagtagcaaa taaagatatt atgattagaa
    21541 atatgtttat agtgtggtta tttactggaa tatggcatgg agcagaatgg acatttgtaa
    21601 tttgggggat tttaaacttt gttttcctaa ttatagagcg atttataatg tttgaaaaga
    21661 ttgaaaatca caattttata aaacatattt atgctttatt agtagttaat tttgggtggg
    21721 tattatttag gtcacctaat ttaaaagaag catataatta ttttaaagct atgtttggag
    21781 gcaatggagc tatatggagt gattatacat atatgttttt aaaagaatac tgggttttct
    21841 ttatatttgc atttattttt agtgtaccta ttgcaaagaa aatcaataag tttgttgttg
    21901 aacaagctaa atatagtatg atatttaacg tattttatcc aatctcagct attttattgt
    21961 tttttatttc tgtgacatat ttagtaactg gaagctataa tccatttatt tattttaatt
    22021 tttagttggg aggaaaagta tgaatagatt ttttaaagta agattaataa ctgcaattat
    22081 gttcttaatt attttattcg ctttctctat ctttaatgtt tgttattctg gaaaagatac
    22141 gatacaggaa ataaaaaatt caatagctga aaaaagtagt ttaaaagata caatatcatc
    22201 tattgataat acagtgaatg acaaagtaat atacaaaaat acgttcattg aaacttatgg
    22261 ctatttacaa aaattaatgg gtaaaaatga gttttcaaaa tttagtgttg taaaagatac
    22321 ttctggaaag atgcattata catattttgc taaagctcca aatccagttg gtgtgatagc
    22381 agatagggta agaaaatttt ctgatgaaat ggaaaagcaa aacactaaat tggtttacct
    22441 aatgactcca gataagtata taaaaggagt gacaaaattt ccaaaaggaa taccttattc
    22501 ttatagtaat gagacagcag ataatttttt aaatcaacta aaaaagtata atgtggacta
    22561 tattgatttt agagaaaata ttttaaagag tggtattcca aaagatgatt tattttttaa
    22621 aacagaccat cactggaaag tagaaacttc tttttgggca tttggagaat tagttgagca
    22681 acttaataaa aaatacaata tgaatttaga tgaaaatcat tattatagag ataaggacaa
    22741 ttataattca attgtatatc ctaagtcatt tcttggttct atgggaagaa agactggtat
    22801 cttatatggt ggtatagatg attttacatt aatttatcct aaatttaaga ctaattatac
    22861 ttattataca gattctaaat ctcaaaaatt tgaattaaaa ggaaggtttg aagagagttt
    22921 aatattatca tatcctttta atgcagacct tgatttaatg gatggtcaat cagataagta
    22981 ttttacatat ttattgggga acagaccatt agttaaaata aaaaatatag aaaatccaga
    23041 tggattaaaa gtgctgtttg ttaaagattc tctaattgta ccaacagcag catttttttc
    23101 ctctgtttgt tcatctatag atatgataga ccctagatat tatgatggag atatactaga
    23161 atatgcaaaa tcccatgact atgactttgt ttttatatct gtatatcccc aaaatcttac
    23221 aaaagaattt tttccgtttt gtgagtaaat ttctaaaaaa gttttctgat aaaataaatg
    23281 gctaactggt aaaaagttag ccatttattt tgagtgttat tctaagaaat atttttttta
    23341 ctaaatactt ctttatctat ttttccaagt gattttccta cagtaattga tgataccata
    23401 gcaccattaa catttatcat agtacgtccc atatctagta tagggtctat tgcaagtata
    23461 ccaccaacta atggaaaata agaaccaaga ccaactccag agataacaac tgaaacggcc
    23521 attgtagcag ttcctggaag accagctatt ccaaacgaac taattgttat aacaattaac
    23581 aacataacat aaaagctcat atccatgttt actccagcca tattggcaag tgttacagcc
    23641 attaaagcag gatatatacc tgcacaacca ttcataccca tatttgcacc taaacttgct
    23701 gtaaagcttg atacaccctc atcaactccg tgattttgta ctagactttc tatcgttaca
    23761 ggcaatgttc ctaaactaga acgtgaagta aatgccagaa gtaaagcttc agttgaattt
    23821 tttatataag taatgggatt tagaccattt aaagttataa aaattaaatg tataataaat
    23881 aatattgcaa ctgatatata aagagctaat ataaactgta aaacagatac tattgaacta
    23941 ataccttgtg aagttattgt atttgcaagc agagcaacca cagcataagg cataaattta
    24001 ataacagtca tagacacact tacaattatt ttgtaagatg cttctataaa acctataaat
    24061 ggttttattg tttcaaaatg ttttttactt aatctcttta ttgaggtagc tataaatgta
    24121 gcaaatatta ttgtagctac aatatttcca tttgccatag ccattacagg attagatggt
    24181 agtaatcctc ttaaagtatc cacaagagag tttatttctt taagttcttg attttcaact
    24241 aaagtaggca tattagctcc tacacctaac ttcattatat ttgcaacgat aattccaaca
    24301 attgcagcta tagcagtagt agcaagaagc atacctaaag atttaaatgt cagagttcca
    24361 agattgttat ctttcatatt tataattact tttataatgg ataagaaaac taaaggtact
    24421 actaacattt ttaataagtc cataaatcca gaaccaaata ggctatacca cttacttact
    24481 tcttgtagcc aaatgacttg agttgtatca ttaggaaaac cagcaaaagc ttgtattatg
    24541 attcccaata tgagtcctag tactgtagca tatattgttc tcaatgaaaa ttttattttt
    24601 ttcttttcaa attgtctaac aataaagaac gtacctagaa gtaatattat gaaaaaaatt
    24661 gttttaaaat ctgtaatcat aagaaattgt gataaaaatg aactttccaa tatttttctc
    24721 cttttattta aaaataaatt tttctaagtt taaatgatat caatatatta aaaaaatgtc
    24781 aatattatat cacaatttac ttaaatagag taaaacaagt tgattttgaa aaatgtgatt
    24841 aagtacagaa aaatagggta taataaatgt ttaaagaatt tgaattgtgg taagaaaata
    24901 aaaaatagct tttataagat ttgatttcaa attaaaatgt gttaaataaa taactaaaaa
    24961 ttattataaa aaatgttttc atagaatata tatcaaatga aaagcttaaa ataagtgaag
    25021 aaattaacta gacatcaaag gagagataaa atgagagtaa taataattgg tggtgttgca
    25081 gctggtatga gtgctgcagc aaaattaaaa agaataaaac ctgagtatga agttgttgtt
    25141 tatgaaaaaa ctgaaatagt atcttttggt gcttgtggat taccatactt tgttggtgga
    25201 ttttttaatg atgctgatga attattagca agaacaccag agaaacttag agaagctgga
    25261 attgatttaa atatatttag agaagtcgtt gaggttgata gtgaatctaa gaaaataaaa
    25321 gtaaaaaaca taaaaacaga tgaaatatat gaagattact atgataaatt gatgatagca
    25381 actggagcaa gaagtattat gcctcctata aaaaacataa aattaaagaa tgtttctaca
    25441 ttaaaaagtt tatatgatgg agaatattta aaaaaacttt taagtaatga agataataaa
    25501 agagtgacaa taataggagc tggttttata gggttagaag cagttgaggc atgtaagaaa
    25561 ttaggtaaag atgtagatgt aattcagtta gaagatagaa tattgccaca agtatttgat
    25621 aaggaaatga cggatgtatt agaagaagaa ataaatagac ataatgttaa tttgcactta
    25681 gatgaaatgg ttgtagaact ttgtggagaa gataaagtag aaaaagttat aacaaacaaa
    25741 ggggaaatag atacagatgt agtaataatt gctactggcg tgagacctaa taccgagttt
    25801 ttgtcaaata ctaatataaa aatgctaaaa aatggagcta tagtagttga tgagtatgga
    25861 agaacttctg tagaagatat atactctgct ggagattgtg caactataaa gaatatagta
    25921 agtaatgaaa atgtatatgt tcctttagct actggagcta ataaattggg taggatagta
    25981 ggagaaaacc tagcaggaag agaaatatct tatcaaggtt cactatcttc aagctgtata
    26041 aaaattatgg atatggaggc agcatcaact ggaattacag aaaggcaagc taaagattta
    26101 ggcataaatg tcaaatctaa atttatttct gattataatc aaactcatta ttatccagga
    26161 agaaataaaa tatatgtaaa gcttatttat gatgcagata caaaagttat tttaggcgga
    26221 caagtggctg ggtttaagga tgctgtccaa agagcaaatg tattggcagc tgctatcttt
    26281 ggaaaaatga ccacaaatca acttggaatg ttagatttat gttatgctcc accatttgca
    26341 agaacatggg atgttttaaa tgtagctgga aatgtatcta aataatattt agattatagc
    26401 taatatagtt gacaagcaat taagggaatg aatttaccta aactattttt atcatggtaa
    26461 aattcattcc taaattttta ttccaaattt ttattccaaa tttttagaaa taaggattcc
    26521 attaaattat tcatcaaaat ttaaacgcaa gcttaatcta tcttctccaa gaatagtatt
    26581 ttcaaaaaca ttagtagcat tttctaaata catactaggt atgtctaaag aaggactaaa
    26641 atgagtcagt aaaagttgtt tgacatttcc aagttttgca agattagcag cttctctaaa
    26701 agtcatatgt ttgtttctaa cagcttttga tatatctaaa tcatcaccat acatggcttc
    26761 acatataaat aaatcactat cttttatgaa atctggtatt gattctatag gtcttgtatc
    26821 ggttgtaaga cttatcttaa ctccctttct caattctcct aagaccatat ctggagtgta
    26881 ttgttttgaa tctaaaacta tattttgacc ttcttggagt ttgttccata atattttagg
    26941 aacttcgttt ttagttgcct tatctatatc aaatttaggg tttcttctaa aattaaaact
    27001 gtatcctaaa cactctatag agtgttctaa actgattgtt gaaatttcta aatttcttaa
    27061 aactttatta tctaaagaaa aattgccttg agggttttct ataattttta aagtgtatgg
    27121 tacatattct actaaatttc tcatagaacg tatacaatcg actattccaa ctggaccaac
    27181 tatagttaaa tcacttgtac gaccactatt cccaattgtt gataaaagtc ctaaaagtcc
    27241 aaatatatgg tcaccatgta aatgggttat acaaatcaag tctatatctt taaagccaca
    27301 tttttttagc ttcatagata cctgagtacc ttcaccacag tcaattagta tttttctacc
    27361 tttatagttt ataaatacag aggatagaaa tctgtttggc ataggtacat ttccaccaca
    27421 tccaagtaaa gttaaatcta tcattttttc ccctttctaa aattaacaca aatctgttgt
    27481 ttgtttttat tatgatatcc tattataatt attttaacat taaatataac aataaatgtg
    27541 tatttgagtc aagaaatatt gtcaaataaa gtttttatat agaaatgtat aaaaatttgg
    27601 aaaacaaaaa gtgaaaatta tatttaggag catttaaagg aggaaaattt aatgaaagta
    27661 ttaaagaaaa ttactatttt gtcattgatt acattaacct tagttggttg tagtaacgga
    27721 gaagataaaa aagtggttga aggttctaag aaaattcaaa attctaaaaa agatgaacag
    27781 cctataatag tacataaaga tgcaaatata ttgaaagata ggtatgagcc accaaaagga
    27841 tttaaaagag ttgatgtaga aaaaggtagt tttgaatcat ttcttaggaa tactaagcta
    27901 aaaaattatg gagagaaagt aaagtattat gatggaagaa ctaaggaatc aaaaggtatt
    27961 tatgatagtg tatttgatgt tgatattggc aatagagatt tacatcaatg tgcagatgcg
    28021 attatgctta tgagagcaga atacttgtat cagaataaac tatatgatga aataagtttt
    28081 gattttgttg atggttttaa ggcgaagtat tcaaaatggg cacaaggata tagaatttca
    28141 gtaaaagata gtggttcaag ctggtataaa gcaactgaat attcaacatc ttatgagagt
    28201 tttagaaagt ttatggatat agtgtttgca tattcaggaa cgttatctct tgaaaaagaa
    28261 ttggagcctg taaaagttga ggatatgaaa ataggagatg tgtttatagt tggtggaagt
    28321 ccaggacatg caagtataat tatggatatg gcagaaaatg aaaagactgg tgaaaaggta
    28381 tttatgatag cccaaagcta tatgcctgca caacaaacgc aacttcttat taatcgtaaa
    28441 aatccaaatt tgagtccttg gtatagttta gattttgaag gtgatttgac aatacctcaa
    28501 tggactttta aaagagacca gttgaaaaga ttttaaaata ataattttat ataataaaag
    28561 aaaaatatag atgtgaaaaa atgtaattag attaaaacta attggatatg gacaaaatta
    28621 aattgataga taaatattaa aaattacact aattaatctt actatagttt aatatttatc
    28681 taaaaagttt tatgtaaaat ataaatttta tattaaagct aaaactaatt tgaggaggct
    28741 aatttatatt gaagattaga aggtatttaa ttttggtaat tataattcta attacaacaa
    28801 gtcagagttt tatttcttat gggctagagc gatttgaaga aataaccatt tttcacacta
    28861 atgatataca tggaagatat gctgaaggtg atgaccatat acaaatagga aatctagcca
    28921 cattgaaaaa agaaactcca aactcaattt tagtagatgc aggagattgt ttgcatggac
    28981 ttccaatagt aaatatggat agagggaaaa gtgcaattga attaattaaa tgtgctggat
    29041 atgactatat tactcctgga aatcatgact ttaattatgg aaaagataga ctgtttgagt
    29101 tatctaaaag tgctaattta ggagagaata ctttaaaatt tttatcatca aatatttttg
    29161 aaaatggaaa aaaagttttt gatagtaatg atataaaaga aatagatgga ataaaaatag
    29221 gattttttgg actctcaacc caggaaacaa agagcaaaac tggatttaaa aatgtggaag
    29281 gattagagtt taaaaatcct atagaaagtg caacagaaca agtaaatgaa ttaaaaggaa
    29341 agggtgccaa tgtaatagtt gcaatatgtc atattggtac aaatagttta agtaagccaa
    29401 atagtataga tatagcaaat gaggttcaag gaattgattt gattattgat ggacacagcc
    29461 acactaagtt tgaaaatggt aaacaagtgg gtgatacatt gattgtaagt gcaggacaat
    29521 atttagaaaa tattggcgag ataaaactaa ctttggatac taatgatgta gaaaatataa
    29581 aaatagaaaa taaatcagtt agattaattg gaaaagaaga agcattaaag tataagcttg
    29641 actccgctgt aagtaaaaag gttgatgaaa taaaagaaca acaagaaaaa atattagata
    29701 aagttatagg ggtaactaca aatactctag atggttcata tgaaaatgta aggacaaaag
    29761 aaactaattt gggtaattta ataagtgaca ttttactaga taaaactaag gctgatattt
    29821 ctttatttaa tggagggaat attcgagata cgatagaaaa aggcaatata acaagaagag
    29881 atattgtaga tgtatttcct tttaacaata ctatagttac caaagaactt acaggagcac
    29941 agattaaaga tgtattggag catggagtaa aactttaccc agaaaaaagt tcagcctttt
    30001 tgcaagtggg aggaatttca tattacttta atcctaaaca aaaagaaggc gaaaaaataa
    30061 caaatattca aaaagaagga aagccattag atttaaataa aaagtatgta gttgcaacga
    30121 atgattatat agcatcaggt ggagatgaat ttccttgttt ttcaaaagag ccagtactaa
    30181 aggaatttgg aaatttagag agtgcagtca ttgaatatat agagtacaaa acagaaatat
    30241 caaaaaatgt agatggaaga attggtatta aatctaaaga tgagttaata agcaagaatc
    30301 atgagagtga tttgatatta agtgaaaatg aaaaaaatat caatgataat gaagagaatc
    30361 tatctaataa tataaaaagc tctgatagtg ataaaaataa aagcttagat aaaacaagtg
    30421 ctagagaaag ttctaatcta ggaatatcta aaagagaagc taaagaaaaa tctcctaaaa
    30481 caggagattt aggtttttca aatagtataa ttatatttat agtttcaagt acattgatat
    30541 gtttattgaa ttttaatcaa aaagagttaa aggataaaaa gtcaaaataa aaattaatga
    30601 gcaaaaacta gtagatagta atttaatttt agataatagt aaacagcaaa ggaaattagt
    30661 tatataaata ctaatttcct ttgttttatg ttttaacatg attactttta aataaaattg
    30721 tattttatga aaaataatta cactaaatgg catagtatta tggggatttt tagtttttat
    30781 tcaagtaaat gaaatcatat taacaacttc tgatatattt acaaattgat aaaaaaatga
    30841 ttttattagt atgatataat ttagctagta tatatgatga tggaggatat agggatgaat
    30901 aatatattac ttttggaaga tgacaaatct ttaaatagag gaattagttt taaattaaaa
    30961 aaagaaggat acaatgtttt tagtgcattt ggtatagaag aagcaaaaaa tattttcgca
    31021 aaagaagaga tatgcttaat tatttccgat ataggtctac ctgatggtag tggttttgac
    31081 ttttgtgagg agattagaaa gaaaagtgat gtttacataa taatgttgac agctcttgat
    31141 gaagaggtgg atattgtcac aggatatgat ttaggtgcag atgattatat cacaaagcct
    31201 tttagcttga tggtattaat atcaaaagtg aatgcgctta tgaaaagagt aaatacagta
    31261 aaaaattata ctctattagt ttgtgatgat ttattctttt attatataga aaataaatta
    31321 attataagaa cagatgataa ggaagaagag ataattttaa gtaagacaga gacaaaacta
    31381 ttaaaatatt tgatggaaaa ttctatgcag acattgacta aagagcaact gttagaatct
    31441 ttatgggata gtagtggtaa ttttgtagat gataatacga ttgcagtaaa tataagaaga
    31501 cttagacaaa aggttgaaaa aaatccatct gaacctaaat atataaaaac agtaagaggg
    31561 gttggatata tgtggggaga aaggagtata aaaaaatgct aaaaaatatg aacctcaaag
    31621 atggtttaag tgtgaaagat gattatataa tgagaagagt tattgtatat tctgttttat
    31681 ctgtactaat agtaaccctt gtatttatac tttttgaata tagcagatta cataaattgt
    31741 atgaacatca aataaaaaat actcaaaata ttgctggaat attgattgaa aaatatccta
    31801 atgatgaaat agatatagta aattctattt ataattctga ttatagtaag gtgtctactg
    31861 gagaaaaggc atttaagaaa tttggctatg gattggaaaa taaaatgtca aatgataaaa
    31921 attttagctt atacttaaaa tcttttttta aggaatcatt ttttattttt ttaatgatgt
    31981 ttatagtagt tataggtata atatattatt ttataagata cataaataaa agattgagta
    32041 aaatttattt tatagtagat aagatgtcac aagaaaacta cttgaaggac actactgagt
    32101 cagaagaaac tggttatcta gtagaatata atgaatactt taaagaaggc atatttagta
    32161 agataaataa ctgtctatat gagcttaata gaagtttaaa gataaagttt attaaattag
    32221 aaaaagaaaa agaaagtgta aaatcattag taacagatat ttcccatcaa ttaaaaactc
    32281 ctttagcatc cttaaaatta tacaatacat tacttataga agaagaatta gaagaagatg
    32341 aagccaacga gttcttattg accaataagg cttctataaa taaattagaa aatttaataa
    32401 attctttagt gaacatatca aggttagaaa ttagcatgat aaacataaaa aaagaagata
    32461 atgatataaa aaatactatt ctaaatgcag taaaaagtgt tacccctaag gctaagagca
    32521 aaagtataac attaaattta aatgaattta acagtagaat tataccacat gataaaaagt
    32581 ggactgagga gagtattttt aatgtattag acaatgctgt aaagtataca caggtaaatg
    32641 gagaaataaa tatatctgta gaagaaactg ctaatttctt taaaattata atagaggata
    32701 atggcatagg gattgaaaaa aatgagttta ataatatatt taaacgtttt tatagaggtt
    32761 ctgctgatga aattgaatct gtagaaggta gtggggtagg attgtattta agtagaaaga
    32821 ttttagaaga acaaggtgga aatattatag tttcttcaaa agtaggaata gggagcaagt
    32881 tttctttgtt tcttacaact atgtaatatt aaatgaaagg aaaatgtaag cctctacatt
    32941 tattatataa gtataaacag ctccagaaat aaaaaattaa taaaatatgg ggtaatataa
    33001 cttagaatga gaggataatt ttatgaaaat actatatact gaaaatttat caaagcatta
    33061 tggaaaagga gaaagcttag taagagcttt ggacaatgtt gatttagaaa taaatgaagg
    33121 tgaatttgtt gcaataatag gaaaatcagg ttctggaaaa agtacacttt tgcatatgat
    33181 tggaggtctt gatataccta catctgggaa ggtgtatata gataataaaa atatatttac
    33241 attaaaagaa gaagaacttg ctgtatttag aagaagaaaa atagggttta tatttcaaag
    33301 ctataattta attccatctc ttaatgtatg ggaaaatgta gtgttgccaa tcggtttaga
    33361 tggtagagag gtagatgaat cttttataaa agaacttttg aaatcattag gacttgaaaa
    33421 taaacacgac gttttaccaa atacattatc aggtggtcaa caacaaaggg tggcaatagc
    33481 aagagcatta gctacaagac cagctataat acttgctgat gaaccaactg gaaacctaga
    33541 ttctaaaaca tctgatgagg ttatgagtat attaaaatct atgtctaaga agtacagtca
    33601 aactctagtt atgataactc atgatgacag tatagcccaa atggctgata gagttatatt
    33661 catagaagat ggcagggtgt caaaggttgg tgataaaaat gattaatact actaaaatag
    33721 caaaaagtaa tttaaagcaa aataaatcaa aaagtattct aataataatt actataatac
    33781 tttcaacctt aatgctttct tctattggaa tttatattgt tgatgcagga gcatatcaaa
    33841 aagaaaatac tataaagtat tcaggcaatt atcaaggtat attagcaaat gtagatgaaa
    33901 aacaggctga tatattgagt aatcatgcag atgttgaatt aactggtgaa atgaatggag
    33961 taggtgttga aaaactggaa gatgattcaa atatttctct agcatacatg aatgaagatg
    34021 ctttgaaatt aaatagtttt gaatttatca aaggaaaatt gccatcaaaa gagaatgaaa
    34081 ttgtgttaga tagtggagct ttaaaggcac ttggttataa aaataaagat ttaggtgaaa
    34141 agataaaaat atcttatgat gactataaaa gtgataaaaa aattgaaaaa gagttcatta
    34201 taagtggaat cttaaaaact agcgaaatat ctgaagcagg taaatattat tatgctatta
    34261 tatcagaatc atatatgaga aatactagag atatgtcgca agaagatttt aatatatatg
    34321 tgaaattaaa tgataaaagt aatttatcga tagaacaagc aaaatcaaaa ttaaataaga
    34381 ttgctaatga tgtaggattg gacactatta atgtagctgt aaatgaaaac tatataaatg
    34441 ctttaaaacc agatatggaa acaattatgg gtggagtatt tgtagggtta gtaattgtat
    34501 tgtctagtat tttagtaata tacaatatat tttatatttc aatagttaca aaggttcaag
    34561 aatttggaaa gcttagagca attggtgcaa ctaaaaaaca agtaaaaaat atagtattta
    34621 aggaagggtt catattagcc ggaatagcaa taccaatagg aataatttta ggctatgtac
    34681 ttgcaaatat tataataaaa tcatttatgg atatagatgt aaaatcatca cgattaccag
    34741 ttatattatc ggttgtggta ataagcttta tatctgttgt tttatcactt ttaaaaccaa
    34801 tgaaagtagc atcaaaagta tccattgttg acgcagtaag atatacagga aataaaataa
    34861 gtaataagag taagagaaaa ggatataaaa atataaatct aaagagatta tcacatgcca
    34921 atttagaaag aaataaaaaa cgtacttaca tgacattggc atcacttata cttagtggaa
    34981 ctatatttat aacagtatca actgccttag aaagttttga tgctgagaaa atggcaagag
    35041 aacactttcc ttatgatata gaagttagac tatctggtta tgaaatgaac agtgataaaa
    35101 atcctaaaga taatttgaat attttacaaa tggataatcc tctaagtaaa gattttttta
    35161 atcaaataaa gaacatggaa ggaattaaaa gaatagaatc tgcaagaagt gtaaaaattg
    35221 gtatggagga ctatgatgtt gaatttaagt atgacctttt acaaagtata aatgaaaatg
    35281 atgtaaaatc attaaacaag aatataatag atggaaaaat aaatcttgaa agacttcaaa
    35341 ctggagatga aatagtaatt actcatgttg atacagcaaa agaaatggga gtaaaagcag
    35401 gagataaaat aagattaact ttatatgatg gagataaaaa gataaaaaaa gaatttaaag
    35461 ttcaagcaat agctatgggg gttccaagtt ttggtatagg gaaggatttt attgatagaa
    35521 ctttgaaata cgattcaact agtagcttgg gaatatatac agaagaagga aagtatcaag
    35581 aaatcaaaga tagtatcaag aagattgcta aaaataatgg atttttagag actgatttta
    35641 tagatagtag aattgagtca aataaggcta ctatttcatt tataaagata atgggataca
    35701 cgctaacagg cataataggt gtgattggat ttatgaatct tgtcaacaca atgataacta
    35761 gcatagttac tagaaaaaaa gaacttggta tgcttcaagc tattggtctt actaataaac
    35821 aattagtgaa aatgcttaat tcagaggcaa tgtattacac ttctggaatg atgataggaa
    35881 gtattctatt tggaggtata ttagggtata ttgctgttat atttctaaaa aagactggat
    35941 tatcttatgc aacatattct ttgccaatag taccaatctt gttgatgatt gtgtgtattc
    36001 ttatagctca atttataaca acttatttga taggacgaag ttttaataaa gaatctctta
    36061 ttgatagagt aagatacagt gaataaaata caaatattta tggttagttt aactagcaaa
    36121 aaacatataa aaaaatatag ttaaagagat tcataattaa ataggttaaa gcatagtaca
    36181 gagcaaacaa tttaagcaga tgtttgctct gtattttatt atgtaatcaa taatatatct
    36241 aatatactga tattattcat gttagaaaat gtaccggtac aattctaaaa aagtataaaa
    36301 ttgtaccata taaaatgaaa attttgtata ataatcgtat agaaaataaa taggagctga
    36361 tatatatgaa taagaagatt aattatgcac caggaccaac tgaaactagg gaaaatgtaa
    36421 gattagcaag agcagaaaaa acaacaaatc cagatataga tattgatttt gttgaatttt
    36481 ataaaaagac atgcgagaag tttggtaata taattggaac aaaaaacgat gtttacatat
    36541 tgagtggtga aggaatatta ggtcttgaag cagcatgtgc atcacttaca gaaaaaggag
    36601 atagagtact tgtaattgac aatggtatat atggagaagg ttttaaagat tttgtaacaa
    36661 tgtatggtgg ggagtatgtg cttttttcaa gtgaatatac taaaagtata gatattgatg
    36721 aattgaaagc atttttagat gaggatagta attttaaata tgcaacagta gtgcattgtg
    36781 atactccaac tggcgtatta aatgatgtaa gcaaaatatg tccattactt aaagaatatg
    36841 gaatattaac tgtagttgat tctgtagcag gtatggtagg agaaagatta agtgtagatg
    36901 aatctaaaat agatataata ttaggtggtt cacaaaaagc tatttctgca ccagcaggac
    36961 ttactatagt cggaataagt caagatgcaa aaaattgtat aaaaaataga aaaactgatg
    37021 taataggttt ttattgtaat ttaaatatat gggaaggcta ttatgaaaaa aaatacttcc
    37081 cttatacaat gccaataagt gacataatgg ggcttgataa agcacttgat aatatattag
    37141 aagaaggaat agaaaatgta ttaaatagac atgaaaagat agcttatagt gttagaaaat
    37201 ctattgagga atatggtcta gaactatttt tagaagaagg atattctaat acagtcacag
    37261 ctataaaaat tcctgaaagt ataggagctt tagaacttac tgattatatg cttaaaaatt
    37321 ataatacact tgttgcaaca tcactaaatc aatatatgga tactatttta agaataggtc
    37381 atatgggaga gaatgcaaat ctaaataaaa tagaacatgt actaaatgtt ttggataaaa
    37441 gtttaagtgc attaggattc aaaggaaatg gaaatttgtt aaatttattt aataagtatt
    37501 atttttaata gataggggga tatagtatgg aagttacagc taagcaaaaa tttacaacga
    37561 aagacatggt ggaaacctca ctattaatag cattagtatt tattgcaact aaatttataa
    37621 acataagatt accaatatct ataaatggtg ggcttgtgca tttaggaact gcaatgttgt
    37681 tcatatcagc aatagtattt ggaagtaaaa aaggtgcttt atcaggagct attggtatgt
    37741 cactttttga tttgatatct gggtggactt tatgggcacc gtttaccttt atagatagag
    37801 gagttatggg ttatttactt ggaaagattg catgggcaaa tggtaataat gggaataatt
    37861 ttttaatcaa tgtaatagga atatgtgttt catcaatttg gatgctattt ggatattatg
    37921 taacagaagt tatactttat ggtaatttta tagtacctct tacttcaata ccaggtaatt
    37981 taatgcaagt attgataggt cttataatag cgcttcctat ttctaaggta ttgaaaaaat
    38041 gtataaaata aatataaagt gaactaaaat ttatgatagc ataaattata ctgtataata
    38101 ttaggatgga gtacataatt aaaaaatttt agtatagagg ttagttcaca atgttatcag
    38161 ttacaagata ttcaatcaaa aatgttcgtt taaagccgtg ggtaaagttt atttggtatt
    38221 ttgagacaaa atcaaatata ctgttaaata ataagttact tccgacagac agtatagata
    38281 ttattctcaa tctttctgat gttatggaat ataaaattga aaatcaagac tatattgcta
    38341 gtaatattca ttttaatgga ataagggata aacatggatt tattattcaa catggaaata
    38401 tacgtgttat agggatttct ttttatccat ttggtctcta tccattttta aagataccaa
    38461 tttcagagtt taacagacaa attgttgacc tagaagcagt atcaaaacta tttgcaaaaa
    38521 aattagaaga gtcattaaat ccaacaaaag caatagaaaa agttgtttta tgtttagaag
    38581 aagtattatt atccatatta gaagaagatt taatttcaaa taaatatgta aagcttctaa
    38641 attcatttat atatgttaat agatatagca atataaaagc attttgtgat gatacaaata
    38701 taaatattaa aacattggaa agaatctgtt taaaatatac agggtataca cctaagattt
    38761 taaagagaat ttacagattt aaaatggcaa gcaatcaact tatttataat tataaagatg
    38821 atgaactttt tgattttatt tatgaaaatg agtactatga ccaagcacac tttataaaag
    38881 aatttaaaaa attttcaggg acgtcaccaa ttaaatttag tggtgagaat aagacgatta
    38941 aagaaaatat aaagtacagc tatttataat tatactgtcg attttttaca atacctccaa
    39001 tttatttttt gatatgatat aggaaaataa attggaggtt ttacatatga aaattattac
    39061 agaaatagtt gagtttaatg tggaagaaaa tttatcaaaa gaagagttta tagaaattgt
    39121 aaatgactta gaattaaaat ttcattctat tcaatctggt tttattgata ctgaactttt
    39181 atatgatgaa aagtctcaaa agtggattat gatacaacat tgggaatcta tagaagacct
    39241 caagagtgtt tctagtaaaa tgtttaaaga ttcttcaact gagaaattta gaaaagcttt
    39301 aaagaatcaa actgttaaga tgaatataat accacaaatt aaaagttgga aattatagaa
    39361 ctgaatgtaa aagatagtta aatagtatca aactaaatta gccaaataac attttgtatt
    39421 taaattgtta tttggctttt agtgtttatt ttaatatgag tgttatatac tagaaaaacc
    39481 aacaaactgt tagagtgtgg attatcataa tgtcatattc gggagctaaa aggcttaata
    39541 ctgatttgcc aattggtcaa tccatgcatg tccatctgga tatgctgtta ttaaagcatt
    39601 tacaagccaa tccctttgct cttgtgataa tagtgggact gttacatcga agtctttttg
    39661 ataaccaagc ctatctatgt atattgattt gcaaaacaaa accacttcgg gagccatata
    39721 tgggatatta tctgatgtta tcagtctggc cttatccata tctcttataa ttctttgatt
    39781 ttgggaaaaa agaaattttc catctttctg tggattatat atcaattcaa taaaatcgaa
    39841 ctgtaactgt tcgtcacact gtatattcat tttatagtta tcatcctcga ctttttttaa
    39901 ttcaataaat gagcaatcag gcttaatcgc aaaaacacaa atttgctcta tatgttgctt
    39961 gttaaggtcg ataataggtc gtaataaata attacccaag ggctcatata tatcccatcc
    40021 ttgattaagc atatactgaa tgctcttttc tttatctgtg tcagaaatcc atatgtcaat
    40081 atcactgtgt gggcgaatat gcatattcgc aaataattct agggcatatc caccacatat
    40141 tgaatatgaa aagccacaat cattaaaaaa gtttacacaa tctttaatta gtttgttcat
    40201 agcaacctcc ttttgcatgt actgaaataa attaaatttt ttaaaatacc aactaaatgt
    40261 ttgttttgtg taaatataaa actgccgata ttaaggcagt tttatattta ctatttagaa
    40321 aatttattaa caaatttttg atattcacac attatcttat cattcataaa agaaataccc
    40381 ataaaagcag cttgctcacc aaacaaagta aaacgttcta tcatctgttg tggattacct
    40441 ggataaactg ttggaataca ccatgtgttt agaagaaaac caaacatttg agcagcaatc
    40501 tctggatttt taacttccat agaattatct tgatttcctt cttcaatcaa tgcttttatc
    40561 caaggcacaa tatcatttat aatctcatca aactgcgtag ctaaatactt aggattacgc
    40621 aatagtgatg atgacattaa aaaaatgtct tgtttattgt gctgttcata agcatgaagc
    40681 aacctatatt gtaatttttc taatgcggtc tttccttcat cattttttac ctcataccca
    40741 taaaatccat cattatacaa ccgacttgtg attgccttaa ttatttcgtc ttttgattta
    40801 aagtgatgat aaatagcacc tcttgaaagg ccatctaaat tatctacaat gtcttgaatc
    40861 gttgtctgct catacccttt ttctaagaat aacttatgtg aaatatcaag tattttttgt
    40921 atagtattat caggttcttt ttttcttccc aaaaaactca ctcctcgaaa caatcatttg
    40981 gtatgtttat cttagcaaat acataatgat ttgtcaatgt gtctttttag catgttgaac
    41041 aggtatattg ccatgctttc attattttat ttttttgcct tatactggac tatatttgca
    41101 gtttcctaat atatttggct catatttaaa taccattatc taaaagcact attgctgtac
    41161 gagaggcaat aggcatttta gaagaaggag gagttgagct aaagtataca tcataatctc
    41221 ttaagttttc tttttttgtg tttcctccaa actctaccat atcagtattt aatatcgttt
    41281 tgtagtttgt attttgaaac tttgaaatat caactgattg tattagatta gggtggaaat
    41341 taaatataaa taaatatttg cccttactgt acaccaaaat ctttttatca ttatccatat
    41401 gtataagttc atgactattt tggataaaaa tatcactgta ttttgtaagt tcgagcatag
    41461 atttatcaaa atttaataat tgtttatact ttaagttgtt atcttctgaa aggctccatt
    41521 gtcttctggc atacttatag ctccaattgt tgccttctcg tggaaaatca atccactcag
    41581 gatgtccaaa ttcatttccc ataaaattta gatatccttc acctgctaga gaaaaagtta
    41641 ttaatttaat taatttaata agagatattg ctctattgat aacatggtta tttgagttta
    41701 tttccatatt ccagtacatt tccttgtcag ctagccaaaa aataattgtt ttatcgccaa
    41761 ctaatgcttg gtcatgggat tcacaatatc ctatattttt ttctccaggt cgtctagtag
    41821 taagttcata ccacattttg cccaaatccc agtcttcatc agataagtta gagatagttt
    41881 ttatccaaaa atcaggtact cccattgcga gtctatagtc aaatccaatt ccgccgtctt
    41941 ttatagggat acacatacca ggcattccac tcatatcttc tgcaatactt atcgaattag
    42001 gtttaatttc tttcattaat tcatttgcaa attggagata tgttatagct tcaatatctg
    42061 tattcatact aaaatatttt tcataactat caaatgaaac tccaagacca tggttatgat
    42121 ataacattga agttacacca tcaaacctaa agccatcaaa atggtactca tttaaccaaa
    42181 attttatatt tgaaagcaaa aaatgtatta cttcaggttt accatagtta aaaagttttg
    42241 taccccaagc aggatgattt ccctttgaac ctgagtggaa aaattgatgt tcacttccat
    42301 caaactcatt tattccttct aaagtattct ttacagcatg agaatgaact aaatctaata
    42361 aaacagcaat ccccattgaa tgagcagtgt ttatgaggtt ttttaagtct tcaggagtac
    42421 caaacctaga tgagattgca taaaagtttg aaacttggta tccaaaagat gcataatatg
    42481 gatgttccat aatagccata agctgaatgg tattgtatcc agcttttttt atcttaggaa
    42541 gtattttttc agtaaattca ttataagttc caatagattc gctttcagta gacataccta
    42601 tatgacattc atagattagt ggagaagtta tgttttttaa gtcaaaatca ttgtcagtcc
    42661 agataaatgg agtttttggt tgccatattt gtccattaaa tccaccaaaa tctttttgaa
    42721 ttactctttt tatatataat ggtatacggt caaatgtttt tccatttgca gtaacttgta
    42781 cctttacctc tgatttgtga ggtaagctat tttgaccagg aataaatatt tcccaattac
    42841 cagacccaat ttttcttaga ggatgagatt ttctattcca attattaaag tcaccaatta
    42901 gtgacaaact atctgcattt ggagcccatt ccctatagaa gaatccatca tttgtctgat
    42961 gaaatccata gtaaagatga gcatttgcaa aagaactaaa atctttatag tttttcaatg
    43021 tttttgattt catatcctca taatgtttca ttcgcttttt tatatcagat tcaaatggtt
    43081 gtaggtatac atcaatatct aaaattttaa atcttttttg acttttcatt gtatttctcc
    43141 tccataataa atattacatc taaaaaataa tatttatctc atactatctt ctctgtataa
    43201 ttgatatata ttatataatc ctaataaaaa gcttaagcca ccaatgatta atttcataat
    43261 ttacctccct agtatttata cttatatatc gtattcatca aaatttaaaa gtttgtttaa
    43321 aactctttta ataatatcat aatcaaagcc tttataggaa agatgttgag aaattttttg
    43381 atatattttc tttttatctt ctttctttac tctttcatac cttttttttg ctagatacat
    43441 agcattttca aattcagtgt ccttgtctaa ttcagatact gcttcattga ttgtacttct
    43501 attgatacct ttattatata aattctgctt aattctgttt ttgccacatt tatttaggtt
    43561 aacatttgtg ttaacaattt tttgagctaa tacactgtca tttacgagat tataactttt
    43621 aagaaaatct atgaccctct caattatatt ttcatcaaat tctgatgata gtttttcttt
    43681 taattttttt tcagattggt cagcatgaga taaaatattt aatgctttat ttttagcttt
    43741 tatatacatt tcatcatcta aaataggttt taattcttct tcatttattt cattcccttt
    43801 ttttaaatta aatgtataaa ccagttcttt aaatatagca ataaaaaatt tatcatctac
    43861 ataaatatta actctatcat catttctttt ttgttgttct atttttgtaa ttatacccat
    43921 aagtcctcct tttttatatg taattatatt aacaaaagca actaataaaa tttaacaaaa
    43981 aacttatatt tgtatgttat attttatcaa aattaagaca aaatagtaaa aagttatttt
    44041 tattaaaaag taaagcagaa tcatgttaaa taattatttt ttaaagtgtt ttttagcata
    44101 taaatataat tatataccca aaaaaacaaa ttataagctt taagaaataa aaaataatgg
    44161 tacaatagta ttataacatt aaaaggagac aaaatatgag aagtgaaaat ctagttaaga
    44221 tggcagagtt gaaaaatact gaaaaactag agaaatttaa tcgccataaa ggcaaaatca
    44281 aaataggtat attgggaggt acttttgacc ctatacacta tgctcattta gcaacagcag
    44341 aatttattag agacaagtat gacattgaca aaataatctt tataccatca ggaaatccac
    44401 cacataaatt atgtatcact acagataagt atgatagata taatatgaca cttctagcaa
    44461 ctgaaagcaa cgaagatttt ttagtttcaa aagtagaaat cgaaagaaag aaaaggactt
    44521 atacaataga tacattaaaa tacttaaaga aaaaatacaa aaatgcagac atttatttta
    44581 taacaggtgc agatgcaatt tgtagtgttg aagagtggaa agatgtaaag aaaaactttg
    44641 agttagctac ttttatagcc gcaactagac caggaattag tttgttaagg tcacaagaga
    44701 ctatagaaaa actaactaag aagtataatg ctgacattat aacagtttat gttccatcac
    44761 tggatatatc gtccacatat ataagggaac agctaaatga aggcaagtca atacgttact
    44821 tagtacccga aaatgtagaa aattatttat atgaaaataa actatatcaa tatggagatg
    44881 attaaatgaa cttagaaaat attaaccaaa gactaaatca aatgctacca gtggggaggc
    44941 ttagccattc aaaaaatgtt gcaaaatgtg ctgaaaaatt atgtgagatt tatggatgtg
    45001 acaaagaaaa agcttactta gcaggaatga ttcatgattg tgcaaagtat ttaagtgaca
    45061 aggaaataga ggattatgta aataagtatg aaatatattt agacccaata gaggatggaa
    45121 atcgttcctt gtctcatagt gtaattgggg cgtacatatg cgagtatgaa tttgaagtgg
    45181 aagatgaaga tattataaat gcaatcaaat atcatacaac agggagagag gacatgtctc
    45241 ttttagaaaa aataatttac atagctgatt taattgaaga aggaagaaaa ttcccagttg
    45301 tagatacatt aagagaatta gcatatggag ggaagcttga tgaagcactt ttaacttctt
    45361 ttaataatac tttaatgttt gtcatcaata aaaaagaaga gatacatcca agaacagtta
    45421 tggcaagaaa ctatctaatt aaagaaaagt tattataaaa aagctatata aaggcaaaca
    45481 tattaataaa tttaaatttg actatgttac aaaatcgtat taatatgtta caataactaa
    45541 gtgtatttta attaggaaag tgaggaattt ttatatgaca gtggaacaaa tgacaaaaat
    45601 agcatatgat gccatagaag ataaactggg tcaagataca gttataataa atataggaaa
    45661 agtttctagt ttgtgtgatt attttattat tactacagca tcttctcaga gacaggtaaa
    45721 agctattgct gacaatgtgg aagatgaatt agcaaaacta ggattagagc caagaggtaa
    45781 agaaggacaa ggaactcaaa cttgggtact ccttgattat ggagacataa tggttcatgt
    45841 atttaatgag gaaaatagag ggttttataa tttagaaaaa ttatggaaag atgcacctta
    45901 tatagatatt gacacattag cataaacatg ataatatatg ttattataat tagaaaattt
    45961 caaaaattat attaaattga atagactaga gcagtaaaag attatatttt ttcagagagt
    46021 tagtggaagg tgagaactaa tattatataa ctttgaactt actagattaa aatctattct
    46081 ccatggctgg attaaaagct atctaagaga gtctatatat gtagtaggct aattagggtg
    46141 gtaccgcgaa gatttatcct cgtccctaaa cgtaagttta gtgacgagga ttttttattt
    46201 tcaaagaatt atttggaaat tataagtaaa taatactaaa taaggtagtt atacacaatt
    46261 aaaaatagga ggcaaaatat gagcgtatat aattttaaag aagtagaatc gaaatggcaa
    46321 aaaatctgga aagataataa tcagtataaa atggatactg cacaaactga aaaacctaat
    46381 tattacacat tagaaatgtt cccttatcca tctggaaaaa tacacatggg acatgttaga
    46441 aattattcta taggtgatgt tgtcgcaaga ttcaaaaaaa tggaaggata taatgtactt
    46501 catccaatgg gatgggattc ttttggatta ccagctgaaa atgcagctat aaaacatgga
    46561 atacatccac ataaatggac aatggaaaat atagaagaaa tgaaagagca attaaattta
    46621 ttaggtatta gttatgattg ggataaagaa gttgcaactt caacgccaga atactataga
    46681 tttacacaag aaatattttt gaagttttta gagcatgggc ttgcatataa gaaaaaatca
    46741 tatgttaact ggtgtccttc ttgtgagact gttcttgcaa atgagcaagt tgttcaagga
    46801 gcatgtgaga gatgtaaagc aacagtatta aagaaagatt tagaacaatg gtattttaag
    46861 actactgaat ttgcagaaga attacttaat gacttagata tattagatgg atggccagaa
    46921 aaagttaaaa caatgcaaaa aaattggata ggtaaaagta caggagcaga tttagttttt
    46981 gatatagatg gaactgataa atctatgaca gtatttacaa ctagaccaga cacaacttat
    47041 ggagttactt atatggtact tgctccagag catgaattag ttaaagaatt ggttgcaggg
    47101 actgaatatg aagcagatgt tgaagctttt gttcaaaaaa tgcatactat gacagaaata
    47161 gaaagaacag cagctgatgt agaaaaagaa ggaatgttta taggtagata tgttataaat
    47221 cctttaaatg gcaagaaagt tcctctatgg atagctaact atgtattagt tgagtatgga
    47281 acaggtgcta taatggcagt tccagcacat gatgaaagag atagagattt tgctgaaaaa
    47341 tataatttag acataattga tgtaataaca gaagataaca aaatgataaa ttcagaagaa
    47401 tttaatggat tagatgcttc agaaggattt gaaggaataa tcgataagtt agaaaaagaa
    47461 ggtagaggaa agagaacaat taattataga cttagagact ggttagtttc aagacaaaga
    47521 tactggggtt gtcctatacc tgtggtttat tgtgatgaat gtggaatagt tccagttaaa
    47581 aaggaagatt taccagttct tttaccaaca gatgttgaat ttactggaaa aggggaatct
    47641 ccacttacga cttcaaagca atttatgtca acaacttgtc ctcactgtgg aaaaccagct
    47701 agaagggaag ttgatactat ggatacattc gttgattctt cttggtattt cttaagatat
    47761 gtggatagca ataatgaaaa tgaaccattt agtaaggaat tagttaatag atggcatcca
    47821 gtagaccaat atataggtgg agtagaacat gctataatgc atttacttta tgcaagatgg
    47881 tttgtaaagg catttaagag tatgggaatg gtagacttca atgagccatt taaaaactta
    47941 cttactcaag gaatggtact tatggatggt tctaaaatga gtaagtctaa agggaataca
    48001 gtatctccta tggatataat agatgagtat ggagcagata ctgcaagact tttcgtatta
    48061 tttgcagcac caccagaaag agatttggac tggtcagagc aaggtgttga tggatgcttt
    48121 agattcttaa atagggttta tagattggtt gacgagttag cagatgtggt taaaaaggat
    48181 gtagagtttg gagaattaaa ttcccaagat aaggatatga gatatactat acactctaca
    48241 cttaaaaaag ttactgctga tttaagtgaa aaattcggat ttaatactgc tatatcagct
    48301 cttatggaat taataaatga tatgtataaa tataaagagt tagataatat aaacgaagca
    48361 gttataaaag aaggtgtaca aactatagta actataattg caccatttgc ccctcattta
    48421 ggtgaagaac tatggactat gataggtaaa gaaggaagtg tatttgacat agactggcct
    48481 aaatatgacg aaaaagcttt agtaaaagat gaaatagaag ttgttgtaca agttaatgga
    48541 aaagttagag gaaaattaac tgttaactca aatatatcta aagatgagat ggaaaaggta
    48601 gctttagaag atgaaaaaat aaaaggatta gttgaaggta aaactatagt taaagttgta
    48661 gctgtaccta aaaaactagt aaatatagtt gttaaataac tcaaaaatat gaacaaaaat
    48721 ataaatttat aaaataaacg aggctgtctc aaaatagaga taagcctttt ttcattgttg
    48781 aaattataaa tttgttgaaa ttataaaaat agatttgatt ttatacaaaa aaatgattaa
    48841 agaactaaaa agttcattct tatataccct agttgttgtt ttaaatatta ttataattaa
    48901 tgttaaatcg agttaatgta ttaagtggta tgtaaatcat tcagtttcca aagtgttgtt
    48961 catcaaggaa ctgctctaag cttaaacgaa aaaaatataa ttattgtatt ttgaaatttt
    49021 tttctatata atgaaaacag gcaaaaaagg tgcgtatcta tgctttatat gaaacaccca
    49081 gacaacgaaa ttcagattca tataatagct accatgtttc taaaaaggaa cttgtaaaaa
    49141 agatagcgtt tcaacttccc agttgattaa aattatcagc aggaaaacaa gtatggtcag
    49201 cagtggtatt ctaatgggtg ttgtcgatat atccaagttg ggattgtctg aggatgttat
    49261 caaataactt gtgataggtg cagtagatgt ggagattcct gatacggatt tattctcagg
    49321 ggatggttgc ttcgggagat atggagcgta accagtttat tgatatggta accatttttt
    49381 gtctaatttg atgaaagaat cccaagaata ccatacagaa gtaagacagg aattaactgg
    49441 tggtataaac tgataaaggc aaatttaaaa attttgatag gatgatttta agatttatct
    49501 tctattttgt gttttagaaa taattgaaat gttatgagga ggtatgtaca aatggagact
    49561 gtaacaaata atcaatcagg tgtagaaatt caactcagtc tgtttgaagc tatcaaagat
    49621 ttattgttaa ttaatcctat tttcttgttg ggaattatct tgattggtat tttcttagtt
    49681 gtaatattca agaaaaatag tgatattcca aaggtaaaaa catctatttt atcactggca
    49741 atgtattact acttatgttt aacactatcg catattgttg gtatccctac attcagtgaa
    49801 tatataagac tgtcacagtt aggggaaacg ttctttaatc caaacataaa tcttattcct
    49861 tttagtgatg gatttagttt gagttttatt ttgaatattt tactttttgt cccattaggt
    49921 tttttatgtc cgcttatcag caaaaccttt gaacgtttga gaaatacatt cttgattggt
    49981 tttggattat ctctttttat cgaaactatt cagcttttta cgttacacag agcaaccgat
    50041 atagacgact tactcacgaa tgtaattgga acaataatag gctatttctg cttcaaactg
    50101 attgctaaat tgcgaattgt aaaactacat tcagatgatg actctatgga acaggattac
    50161 acagtatgta ttccgattgc cattataata gttgccctta tattaggatt ttttagttaa
    50221 gttccaaata gctaatttgg gaattatgga ggtcattaag tgaataaaat tacttttata
    50281 tgtttaggtg taaaaagtat ggagaagtca attaaatttt atagagatgg attaggattt
    50341 tagattacaa acttttagtt taccaaggag atagcaaagt tgtgtgccaa agggtaacca
    50401 tttggaaatc cagacaacat aacagatagt acgttacctt ttacaggagc atactatctg
    50461 ttatattgtc aacatcctat tttatggttt gtgtgtagtt tcctgtaaac tgaactaaat
    50521 aattaaatag aagctattag aattaataat aacagataga tattaataag cataaacaaa
    50581 tagtaaaatg tgtagatata gacgttttta agtgaaacta ttataaaata attgactgat
    50641 aatcaactga caaaacctat ttttttaggt ttaactgaca tttaactgac agtcagtttt
    50701 tactatttaa atagaagttc gcttagattg tcggaagctt ctttgtccat ttctttaagt
    50761 acatgagaat atctattcat agttattttt atatctgtat gacccaatct ttcagaaaca
    50821 actttcatat tagttccccc taaaagcagc agagtggcac ttgtatatct taaatcatgt
    50881 attctaatct tttttaaatt attttttttg taaaattgtg aaacgttttt cttagtgaag
    50941 aaggtagaaa cggatttaaa ttggtgttta gacaaactaa attatttctg ttttccagga
    51001 taccttacaa ttttaatttg ctttgtctta gttttttaat tttcaatttt tcaattaatt
    51061 cttttggagc tgataaagct ctttttgatt ttggtgtttt tggctcttta aaagatattt
    51121 tgccattaga atagacaaga atttgattaa catttatcag attgttatct aagtcaacat
    51181 ctgaccacct aagcccagta gcttctccca ttcttaaacc tagaagtaac attaaaagaa
    51241 taggtatttc tatattatta ctaagtaact tttctattag caataatact tcttttctat
    51301 tgtatatttc atttgtagaa tatttttctt tagaaggaag ttttataaaa tcacatgaat
    51361 tttcttgtat ttctcttaat ctatatgctt cccttattac agaacttaga aagctatacc
    51421 ttactttagc actagtaaag gtagaattat taaagttata atttacaaaa gcttgtactg
    51481 aactaggatt tacttctgtg agttttagat tcttaaaaag aggttctatg taatttttaa
    51541 cccaagattt tgtatttgta acagtatatg gagaccaatt atttttattc atgtccatgt
    51601 atttataaca tctttctaca aatgtcatat cttttggagc aacaaactta ttattgttta
    51661 tagtagattt tatttcaatt aaatgttttt cagcatcctt tttcttttca taacttccat
    51721 aacttttctg ttttatcttg ccagttgttt cctctatgta ctccacatat acatagaatt
    51781 tttcccctct ttttcttata aaagctgatt tgatattcat atatgtacgc tccctttata
    51841 agttagtttt ataaaagaac agttgtacta ctctaattat gtcattatct ttttaattct
    51901 ttacagttac attataacac gtatttgtat acacttaaat taacaggaag ataaatatcg
    51961 ttaaaggagg aaaagaaaat ttaatgtaga attattaaga tatatagtat ttcatatata
    52021 aaagggggag atattgtgaa attaaagaaa ttattatcac tagggttagt gtcaatgttt
    52081 gttgctggtt ttcctatatc agctaatgca cttgataaaa ttgataaaat tcaaggagca
    52141 gataaatacg aaactgctgg tatcatagct gacaaacaaa gttatactac tgcaatactt
    52201 ataaatgcag atagtacaat ggctgatggg ctaagtgcga gtggacttgc aggagcaaca
    52261 aatgcaccaa tccttttgac taaaaagaat aatataccta atgcaactct taaaagagta
    52321 gaaaaagcta aaaaggtata cataatagga ggagaaagtt ccattgataa agcaacagaa
    52381 acttttctaa aagataaagg aatagagact agaaggcttc aaggtaatga taggattaag
    52441 acaagttata atgtagcaaa agaaataaat tccattaata aagtaaataa agtaatatta
    52501 actaacgctt tcaaaggtga gccagatgct atgagtgctg cacctgtagc agttagagat
    52561 aaagcagcta tagtattaac tgatggaaaa agtgttccat ttaatacaac tggtatagaa
    52621 agttatgcaa taggtggcac ttcatcaatg agtgatagtt tagtaaatga tactaattca
    52681 actcgattgg gtggagtaga tagatatgat actaataaaa aaatagtaaa taagttctat
    52741 aatggcgcaa aagaatttta tatagctagt ggtactgatt tagtttatgc tttagttgct
    52801 tcaccaatgg ctaaaaataa tcctattgta ctagttgata ttggaagtaa taaagatata
    52861 cttaaaaatg ctgcaaaagt aaccgggata ggaaatctaa gtgataaaat tatgctagag
    52921 tgtgaaaata ccatcaataa tattagtctt ccatcttcaa ataaaaatat aatatgtgga
    52981 ttaaagattg attttgattc aaatcacata atttggcaag ataaaggaag ttatcttgaa
    53041 tgttatgatg ataaccttga atattatact gaaaaatata aagacccaac agttcctata
    53101 aatatagaaa atacaagtac acaaaattta gatgtaacaa aattaaaagt ttatggagaa
    53161 gctaattcaa cattatatat ggggcaatac gctaaaataa aaatggattt taatagtttc
    53221 ggtgtattaa agccaggaga aaaatgtact atttatttag atataatttc attagatcca
    53281 tcaagaagca tgacattaac attttcttat gtaggtgata aagaaaatta taaatatgaa
    53341 caaggattgg caagtagaat attattttat aacccggatg gagaagattt ttttgaatat
    53401 aaataactag tgggtatgta aatgtctcga tattgctcat atgttgagtt attatattta
    53461 gtttcatatg aactatatgg attttaaaat taaaaatact taaaaacatt tactttaata
    53521 gtaggtgttt ttttgattaa aagaatatta ttataatgta aaaagtaata aataggtaaa
    53581 atatgtaaga attatatgtt ataatatttt tagcaagaag atgtaatcta caatttatag
    53641 agtggagttc atgtatcaaa aaattatcct cccgacgtta agaagggagg tgaatataca
    53701 tggataattt tttacaaggc atactagcaa gtctatctgc tagcttaata gtttatatag
    53761 ctagcaaact atttagaaag cgtaaaaaac cactcaaagc ggcaactaag agtggttggg
    53821 aatttgattt aaaaatcaga ttccataaaa ctaagtaatt tctaaattat gaactccact
    53881 ctacagcaaa atagattgta gttcttcttg cttttattat atcacaaatt ggtacagata
    53941 ttcaaaaata atatttttat gatataataa agtcatagaa attttgcagt gttcgatttt
    54001 ttgaagaaat taaggcttaa cagttgaaat ataaggcatt gaggacttgt gataagtgtt
    54061 atcaattgca ctactcatgg ttcactgcaa atttgagaga tttgtatatg tgtaggcatt
    54121 ggaaatactc aatttatttt ggggttttat attaactata tggaatgtaa atttcatatt
    54181 ccatgcattc tgcttacact taatagaaaa gttttatatt aactatatgg aatgtaaatt
    54241 atttctagcg acttggtcgg ttgctccatt tagcttgttt tatattaact atatggaatg
    54301 taaatttttt caaatctgat atatcgacct taaatttcgt gggttttata ttaactatat
    54361 ggaatgtaaa tgatataaac tttgggagtt cagaagaagg attaaaaagt tttatattaa
    54421 ctatatggaa tgtaaattag agatgaactc agatagaaaa acatgtagat gtgtgtttta
    54481 tattaactat atggaatgta aattcttcaa cagttgtgtt accatctcct acacgcacag
    54541 gttttatatt aactatatgg aatgtaaatt gctacgtaac cagtttcacc gctttcagta
    54601 tataacgttt tatattaact atatggaatg taaattgttg gtatagtttc agaaaagaaa
    54661 ttcgaaacac ttgttttata ttaactatat ggaatgtaaa ttgtatccaa aaaattacaa
    54721 taatcatacg aactgctaat ataagcagtc aatatatgtg tacatttatc tattttatct
    54781 ctaaatatat aaattattat ccccctaaaa aactttcata aaaacaaaaa gaacaatatc
    54841 tctttggcaa ctggctgaca taactcataa gatatttata taagtcttag tctctatagc
    54901 tttgcgtcac tagatttctc tagttttgcc gatttagttt tattctataa ctaaataata
    54961 caatagaatt agttattatt caataagatt gtttgaaaat tgaataaatt tataggtatg
    55021 aacgtaattt cacacttaaa aaacagacta aatacgtaga atatatagaa aaatttacct
    55081 gtagtttttg tgataaaaag ctcctattat taatttaagc tagataagtt tgaggaagtg
    55141 acataaattg aaagaaggaa tatattatgt tgaataaaaa attaccagat gcagaattaa
    55201 aaattatgaa atacatatag aatactggtt ataaaactgt aatatcaaaa gatgttgcag
    55261 atgaaataga aaaaacatat gcttggaagc atacaactac aattacactt ttagctagat
    55321 taactaaaaa aggttttttc atatcgcaga gaattgggaa acatgtacac tatagagtat
    55381 taataaaaga gaaagaatat ctcaaaatag agggaaaaag aatttttgga ggtctacata
    55441 acaatccatt atcagaatta atttcaaaat tgcatgatgg agaagaaata actgaagaaa
    55501 aaataataga aataggaaat tggataaaaa gctggaaaga tgaagattaa taaataaaag
    55561 gtagctacta atataagtgc tacctttttt cttgtggata atattgggga taagttgtgg
    55621 aaaacttgtg gataaaatat tttgctgaca tttaactgac ataagtatta gattttgatt
    55681 taaaaatgtt gaaatatcaa taaataatta aatagaagtt attagaatta acaatagatt
    55741 cctttttcaa agaaatcttt gatttcatca aggttatcag tttttccaag tgctaagata
    55801 agttttattc tagctttttg acctggtaag tccccaccaa atatacaacc aagatttttt
    55861 aaatctctac cagaaccaaa gtaaccataa ctatcgaata ctctacctga atgacatcta
    55921 gaaactataa ctacaggaag tcctttttct ctagcatatt caactccaga aagcatttga
    55981 ggaggaatat tacctctacc cattgcctca ataactatac ctttataacc actatcaaca
    56041 gcaaatctta taaagtcagc attttctcct acatatgctt taaataaggc aactttagat
    56101 tctaccttat cagtatctat aattgttcta tttacaatat ctcttgtaag gacaagttcg
    56161 ttgcagtcaa ttattcctaa tgggccacta gttagagatt taaatgtatt tagagaaaga
    56221 gtatttgttt tagtagcttc agaagctaat aatacttcat tgtttaaaac tacaaggact
    56281 ccttttccca tagcatcttt ggatactgca gtacaaactg atgcagataa attacttgaa
    56341 ccatcatatc caagttcaga actacttctc atagcacctg tgactattac aggtttgatg
    56401 ttgtcaattg taaggtctag aaaataagct gtttcctcta aactatctgt accatgtgtt
    56461 attacaacac ctgtaatatc ttttcttgct aataaatcat ttacataatt tttcaattcc
    56521 atcattctat aaggtgttat gtgaggtcct ggaatttcat caaaattaaa aacttcaaca
    56581 tctgcaactt tatcaatgtt ggtaaccatt gatagtattt gttcacctga taaagttggt
    56641 atagctgctc cgactttatc atctactgtc atagatatag ttccaccagt aaaaactatg
    56701 gcaacttttt tcttaatact catactattc tctgcctttc ataaataaaa tttataattc
    56761 cgataggatt atatcaaaaa aagtagttaa ggtctacata aactctttta ttcatataat
    56821 ttagatattt cagtgtaata taattatttc ttaatttttt gccattcaac gatataacca
    56881 tttaatatct ctcttatggc ttttcctatc ttagtataag cttcatcata tagatttgct
    56941 agagatattc taattgacca ttcaggacca tagaatccat ttccactaag taaaactact
    57001 gaatagtcat tagctaattt ataaagaaca tctactggag atgcagtttt acttataaat
    57061 ttaaataagt cttctccgta gtttaattta gcccattctt caatatcaaa ttgagtgtaa
    57121 tatgcagcat tgtttttgtt ttcattaatt ggaagctcta aagcttcaaa taatagtttt
    57181 tgacgtctat ggcagatact catattgagt tttttgtagg catctacttt gtcaatcaat
    57241 gcaaaagcag agaaaaacgc catttgtact tgctgtggag tagaaagacc agcagtatgg
    57301 ttgagagcaa caagtctgct atcagcaaca actctttcca taaatgaaag gctagaaggg
    57361 ttaagactca tatcactgta acgcttatct actgattttt ttaattctcc agttaaatca
    57421 tttattttct tatcaaaaac atttttctta tgaagggcaa atgtaccaag tctccatcct
    57481 gtaactccaa aatattttga ataagaatat actccaacag tgttgtaagg tagttttgac
    57541 attaaggatg aaaaatcttc tacaaaagtt ccatatacat catctgatat tatcattaaa
    57601 tctttattat aattttcaat tacatctatt agattattac aagatgtttc atccatagct
    57661 atagaagcag gattattagg attaacaacg aataaagctt taatagattt gtcacgaagt
    57721 ttctctaatt ctttttttgt atattgccat gtatgagcac ctttttcatc aacttcatta
    57781 gcatttatat ttaccacttt aaagtcgtaa cgaggaaggt taggtatttc aagataaggt
    57841 gtaaatattg gagtcattaa ggctatggta tctccttttt ttagaagttc atttgccatt
    57901 aatgaatcaa atatatagca catagcagct gtagcacctt caacagcaaa aatttctaca
    57961 tcaccatatt tacctgatat atcatatttc atttcttgaa ctaggtaatc gtgtactatt
    58021 ttttccatat gaggtaacat tctatctgga agtggatagt tatcaccaat aattccatca
    58081 gctagttcat gaacaaattc atctccatca aatccaagtt catttatacc aaagtttata
    58141 atatctctag ctaaatatgc tccaggcata tctatatttt catttataaa tttaaaaaat
    58201 ctttctttaa tacccttttt ttgaggcatt ccagccaaat gacctaaatc ccaattagaa
    58261 cgagtttcag taatagcgaa atgaccaaaa gtaaaaaagg cttctctagc agttgaacaa
    58321 gtccagtttg gatttccacg acctgcatca agtaattctc tgttattttc ttttgcagtg
    58381 tattttgcaa tatctattaa tttgtcctta aattcaaaag ggcttatttt tccatatatg
    58441 tttttgattt ctttataagt atgatttttc atgttaaatt cctccttatg taataagttt
    58501 cacattttta taataaaata aacaagttgc aaaaatgatt atactttaat tataataggt
    58561 ttatagaaaa agtaaagtat gaaattaaaa taataactct atttagcctt attaaatata
    58621 tgttaaaata aaaaatacct tttaataaaa aatgattgtt at
//
LOCUS       DAMKNB010000017        56102 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.017, whole genome shotgun sequence.
ACCESSION   DAMKNB010000017 DAMKNB010000000
VERSION     DAMKNB010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 56102)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 56102)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..56102
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.017"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            7..81
                     /locus_tag="PC494_001189"
     tRNA            7..81
                     /locus_tag="PC494_001189"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:39..41,aa:Asn,seq:gtt)
     gene            87..172
                     /locus_tag="PC494_001190"
     tRNA            87..172
                     /locus_tag="PC494_001190"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:121..123,aa:Leu,seq:taa)
     gene            188..263
                     /locus_tag="PC494_001191"
     tRNA            188..263
                     /locus_tag="PC494_001191"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:221..223,aa:Met,seq:cat)
     gene            271..345
                     /locus_tag="PC494_001192"
     tRNA            271..345
                     /locus_tag="PC494_001192"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:304..306,aa:Glu,seq:ttc)
     gene            360..433
                     /locus_tag="PC494_001193"
     tRNA            360..433
                     /locus_tag="PC494_001193"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:392..394,aa:Gly,seq:tcc)
     gene            439..514
                     /locus_tag="PC494_001194"
     tRNA            439..514
                     /locus_tag="PC494_001194"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:472..474,aa:Val,seq:tac)
     gene            520..596
                     /locus_tag="PC494_001195"
     tRNA            520..596
                     /locus_tag="PC494_001195"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:554..556,aa:Asp,seq:gtc)
     gene            607..681
                     /locus_tag="PC494_001196"
     tRNA            607..681
                     /locus_tag="PC494_001196"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:639..641,aa:Gly,seq:gcc)
     gene            691..764
                     /locus_tag="PC494_001197"
     tRNA            691..764
                     /locus_tag="PC494_001197"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:725..727,aa:Arg,seq:tct)
     gene            1748..2587
                     /locus_tag="PC494_001198"
     CDS             1748..2587
                     /locus_tag="PC494_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00159 family protein"
                     /protein_id="HDF3911706.1"
                     /translation="MLDINSFLNGFFNIILRMSIYDLIDISIVAYIFYKIFMFIKDTR
                     AEQVFKGIIFLLLATQLSNTFKLHTVYWISLKALDYGVIAALIIFQPEFRAGLEHIGR
                     AKFNLFGKNVNTSEETLNRNIEEIVEALYSLSRQKIGALIIMERETRISDIINTGTII
                     DAEISRQLLINIFIPNTPLHDGAVVIRDSKVKAAACFLPLTESKDLSKDLGTRHRAGI
                     GVSEVSDCITLIVSEETGGVSIAKAGKLYRDISRERMMNILRSNLKTNTETRSFFKGG
                     IFK"
     gene            2584..3765
                     /locus_tag="PC494_001199"
     CDS             2584..3765
                     /locus_tag="PC494_001199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3911707.1"
                     /translation="MINRLKNNTKIKIISFLSAIALWMYVMAVVDPEETKGFEDIPVS
                     ISNMSDLKDKNLVIYPDEKLTADVYIKGSLSKVQSVKKEDIHVYGTIEDPIQGQKEVY
                     LKANIPQGVTLEFKHDVLVVNLEKNIKEKRDIKVEVSGNSKRNINKIELSKEFVDVSG
                     PRTLVKEVKSVRANLDVGNETDDFSKKLQLIPLNSDGTKVEGVTLSSSFVTAKIELLK
                     EKIVPIRVSLNDNKDNDVLKNYKLSKEQVTIKGKKDDIDKISYIKTKPIDLADLANGE
                     EKEVSLEIPEGITLEDSSITIKLNDTKQLSAEFLYNAGDIELRNIPTNMDNPNVISDV
                     DIKVVVESTEDLSKLNKKDISLYIDLSQGPEEDSKYKIKYETTYQFKKINIEPNIVEV
                     E"
     gene            4069..4971
                     /gene="ptb"
                     /locus_tag="PC494_001200"
     CDS             4069..4971
                     /gene="ptb"
                     /locus_tag="PC494_001200"
                     /EC_number="2.3.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate butyryltransferase"
                     /protein_id="HDF3911708.1"
                     /translation="MRSFEEVIKFAKERGPKTISVACCQDKEVLMAVEMARKEKIANA
                     ILVGDIEKTKEIAKSIDMDIENYELIDIKDLAEASLKSVELVSQGKADMVMKGLVDTS
                     IILKAVLNKEVGLRTGNVLSHVAVFDVEGYDRLFFVTDAAMNLAPDTNTKKQIIENAC
                     TVAHSLDISEPKVAAICAKEKVNPKMKDTVEAKELEEMYERGEIKGCMVGGPFAIDNA
                     VSLEAAKHKGINHPVAGRADILLAPDIEGGNILYKALVFFSKSKNAGVIVGAKAPIIL
                     TSRADSEETKLNSIALGVLMAAKA"
     gene            4993..6072
                     /gene="buk"
                     /locus_tag="PC494_001201"
     CDS             4993..6072
                     /gene="buk"
                     /locus_tag="PC494_001201"
                     /EC_number="2.7.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="butyrate kinase"
                     /protein_id="HDF3911709.1"
                     /translation="MSKIFKILTINPGSTSTKIAVFDNEDLVFEKTLRHSSEEIGKYE
                     KVSDQFEFRKQVIEEALKEGGVKTSELDAVVGRGGLLKPIKGGTYSVSAAMIEDLKVG
                     VLGEHASNLGGIIAKQIGEEVNVPSYIVDPVVVDELEDVARISGMPEISRASVVHALN
                     QKAIARRYAREINKKYEDINLIVAHMGGGVSVGAHKNGKIVDVANALDGEGPFSPERS
                     GGLPVGALVKMCFSGKYTQDEIKKKIKGNGGLVAYLNTNDAREVEERIEAGDEKAKLV
                     YEAMAYQISKEIGASAAVLKGDVKAILLTGGIAYSKMFTEMIADRVKFIADVKVYPGE
                     DEMIALAQGGLRVLTGEEEAQVYDN"
     gene            6062..6739
                     /locus_tag="PC494_001202"
     CDS             6062..6739
                     /locus_tag="PC494_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HDF3911710.1"
                     /translation="MITNDKRIRIITGHYGSGKSEFAMNYVVKLRDMVSGKVAIADLD
                     VVNVYFRTREKKELMKSLGIQPIDSSINAPTLDLPAVSAEVMSPMVDHSYNSVIDLGG
                     DNVGARVIGRFSHLLKEGDYDMLFVINANREKTQTSEEVIQYIKEIEKSSKLKVTGLI
                     NNTHLIRFTTIDDVLRGQKVAKEVSEKCNIPIRYVACLENLVEQLPKDLEGEIFPIKL
                     YMREDWM"
     gene            6782..6997
                     /locus_tag="PC494_001203"
     CDS             6782..6997
                     /locus_tag="PC494_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HDF3911711.1"
                     /translation="MAKGKVSFNQERCKGCGLCVEACPVKIIQLDSNVINKKGYNPAT
                     VFEMEKCIGCASCATMCPDVVITVERD"
     gene            7026..8105
                     /locus_tag="PC494_001204"
     CDS             7026..8105
                     /locus_tag="PC494_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-methyl-2-oxobutanoate dehydrogenase subunit
                     VorB"
                     /protein_id="HDF3911712.1"
                     /translation="MAKILMKGNEAFGKAAIEAGCKYFFGYPITPQSELPEYLSRELP
                     KIGGAFVQAESEVSAINMVYGGAGAGARVMTSSSSPGVALKQEGITYAVGAEVPCVVL
                     NVMRGGPGLGSIQPSQADYFMSTRGGGNGDYRTPVFAPATVQEAVDMIMEAFDVADYY
                     RSPVMVVADGMIGQMMEPVEFRAPEKKRELPPKDWATVGTKGKRKPNVINSLYLEPEV
                     LEDHCWHLQEKFDAMEKNEVQYEMYKTEDAEFVFAAYGTTSRVVKSAIDILREEGIKA
                     GLIRPKVLWPFPFEAFNQIPNARNILTVEMSMGQMVEDVKMAVEGKLPVYFHGRPGGM
                     TPTPAEIVEKAKKIIAGELVAGGAR"
     gene            8105..8857
                     /locus_tag="PC494_001205"
     CDS             8105..8857
                     /locus_tag="PC494_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoglutarate oxidoreductase"
                     /protein_id="HDF3911713.1"
                     /translation="MAVVFKKTEGLQDTQTHYCPGCTHGIIHRLVGEVLEELGVLGDA
                     VGVVPVGCSVLGYKYFNCDTQEAAHGRAPAAATGIKRVHPENTVFTYQGDGDLASIGT
                     AEIVHAAARGEKITTIFVNNTTYGMTGGQMAPTTLVGQRATTAQSGRNAETQGYPIRV
                     SEMLATLTGAVFVERVAVDTPAHVRQAKKAIKKAFQVQQAGLGFGIVEVLSTCPTNWG
                     LAPNDALQWLRDNMIPYYPLGNFKNVEVEEVK"
     gene            8858..9415
                     /locus_tag="PC494_001206"
     CDS             8858..9415
                     /locus_tag="PC494_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoacid:acceptor oxidoreductase family
                     protein"
                     /protein_id="HDF3911714.1"
                     /translation="MSTARVICAGFGGQGVMSMGQLLTYAGMLEGKEVSWLPSYGPEM
                     RGGTANCAVTVSNEPVGSPLITDDATAAILLNIPAFEKFKDDVIPGGKIIVNSSLIKE
                     KVDRTDVDVYYIPANELAAELGNDKVANMIMLGAYLKVSDTVDIESVLEAFKKVFGPR
                     KEKFVPLNREALQKGMDATCSKATN"
     gene            9585..10931
                     /locus_tag="PC494_001207"
     CDS             9585..10931
                     /locus_tag="PC494_001207"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HDF3911715.1"
                     /translation="MRKYFGTDGVRGVANTELTCDLAYKLGRAGGFVLAQGDHRVKVV
                     VGKDTRISGDMLEASLIAGLMSVGCDVITVGIIPTPAVAYLTRKYGADCGVVISASHN
                     PVEYNGIKFFNKNGYKLDDEIELKIEEYIDDIDKIDCLPIGENVGRKLHEHCAQRDYV
                     DYLKSIISTDFKGLKVVLDCANGASYKVAPIVFDELGASVISINSSPDGNNINYKCGS
                     THPEQLQRAVLEHNADLGLAYDGDADRLIAVNEKGQIVDGDHIMILSALNLKKNNKLA
                     QDTLVVTVMSNIGLTIAAKENGINLSTTAVGDRYVLEDMVKNGYNLGGEQSGHMIFLD
                     YNTTGDGVLSSLILANIILQEKKPLSEIASIMSQYPQVLVNATIKNENKNKYMEYPEI
                     KTEIERIESILDGNGRVLIRPSGTEPLVRVMLEGKEEGQIKELATNLANLIQEKLS"
     gene            11198..13030
                     /gene="glmS"
                     /locus_tag="PC494_001208"
     CDS             11198..13030
                     /gene="glmS"
                     /locus_tag="PC494_001208"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003401499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HDF3911716.1"
                     /translation="MCGIVGYLGSRKAAEVIVEGLSKLEYRGYDSAGVAVNSSNEKEL
                     NIRKFKGRLSVLAEDLEKNPIDGNLGIGHTRWATHGEPSDVNSHPHFNQAKTIAVVHN
                     GIIENYMEIKEELISEGVKFESQTDTEVIAHLVDKYYEGNLLDAVYKTISKLRGAYAL
                     GVICKEHGNELVAVRKDSPLVVGVGEGENFIASDIPALLKYTRDVYFLENGEVVHLKD
                     ENVTVYDSNRNLVEKEVFHVTWDVEAASKGGYDYFMSKEIHEQPTGVRETLERRLDDN
                     GNIILDSINISKEDLEKINKVYIVACGTAYNAGLLGKYAIEKFVNIPVITDIASEFRY
                     SDPFVDENSLVILVSQSGETADTLAVLRDSKAKGARILSITNVVGSSIARESDDVFYT
                     WAGPEVAVASTKAYTTQITSLYMIALDFAIKKGTITREFYDSMISKMKEIPSKIQEIL
                     DNEEYIKEVAKTVVSSEHAFYLGRGIDYSLAMEGSLKLKEISYIHAEAFAAGELKHGT
                     IALIEKGTPVIAIATQEKLFEKMVSNMEEVRARGAYVVAIAQSHNKDVEKAADKIIYI
                     PNSDDILSPILAVVPMQLLAYHVSVLRGCDVDKPRNLAKSVTVE"
     gene            13482..14777
                     /locus_tag="PC494_001209"
     CDS             13482..14777
                     /locus_tag="PC494_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiosulfate sulfurtransferase"
                     /protein_id="HDF3911717.1"
                     /translation="MTNDFKKEKKEDYFVNLKAISTEVLQEKVQDNAWVIVDTRLNDA
                     YNGWKLDGVKRGGHIKGAVDFSANWLSVYSDRKDEVLEQALKTKRIDLDKNIVLYDAN
                     GKDALVVANYLSKKGYKYLYKYDIKQWADDENLPMERYKNYQMIVPAFIIKDILDGKI
                     PETFEDSKNIKMIEASWGKESYTKGHIPTSVHVNTDIIEPPPTWMLDNDDNLTKFALD
                     YGLTKDDTVIVSSSTPMASYRLAVILRYIGVKDVRVLNGGTNSWLSAGYELEFISNPK
                     HSCTNFGADIPVNSQLIVTTSELRQKLKEKNKFILVDNRTWDEHIGKVSGYTYYDKKG
                     RIPGALYGHSGSDSVSLEEYRNIDNTMRNKYEILEMWDKENIDVNKQLIFMCGSGWRA
                     AEVLTYANVIGVENTSLYSDGWMGWSLDNSNLIEVGEHK"
     gene            15205..15942
                     /locus_tag="PC494_001210"
     CDS             15205..15942
                     /locus_tag="PC494_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YwmB family TATA-box binding protein"
                     /protein_id="HDF3911718.1"
                     /translation="MKKVKLAISFFILMIIGMTISYADTSINTRYNRLSKALEISEAN
                     FKFYNVKINSVINHNLSNKEFHNIFIEIINNLKLDKKGINWNQKGSGDKIQLCATIKG
                     SDKEISIKGINKNNKESYIVVDILDNKVYKHKEVIYSNVENVLNKYSSQVDVSACIVG
                     EYTKRLQNNKYDDILQKILYNMSAKQIDEVKDVNFLSITAYSKVLNDYELEYLGEKIN
                     LNIGIKYNEDDGKTLIYIATPIIKLDY"
     gene            15963..17216
                     /gene="murA"
                     /locus_tag="PC494_001211"
     CDS             15963..17216
                     /gene="murA"
                     /locus_tag="PC494_001211"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HDF3911719.1"
                     /translation="MAKIIVKKSNPLKGSVKIDGAKNAVLPIIAATLLANGKSTLNGV
                     PNLRDVHVISDLLRHVGAEVEYKENTLTVDASNIKTCEAPYELVRKMRASFLVMGPLL
                     ARFNSTKISMPGGCAIGTRPIDLHLKGFKALGAKIEMNHGFVEAATEKLVGNKLYLDF
                     PSVGATENIMMAASLAEGTTIIENAAEEPEIVDLANFLNEMGADVKGAGTNTIKIKGV
                     KELKGAEHNVIPDRIEAATYMVAAAMTKGDITVENVLMEHLKLVVAKLREAGCEITEM
                     DNSVRVVGPKVLKPIDIKTLPHPGFPTDVQAQFMAMLTVANGTGVVIETVFENRFMHV
                     AEFNRMGANIKIDGRSAVVNGVDELHGAAVNATDLRAGAALILCGLIAEGETQIGEIY
                     HIQRGYVDIDKKITALGGQIEIVED"
     gene            17303..18367
                     /gene="spoIID"
                     /locus_tag="PC494_001212"
     CDS             17303..18367
                     /gene="spoIID"
                     /locus_tag="PC494_001212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage II sporulation protein D"
                     /protein_id="HDF3911720.1"
                     /translation="MKNPLVVLLGFVTCSVLVPSLITLVSYKNVELTEKPESPVSINK
                     TIKKSDIEDKGNKEEKNTVNYETVNKKAPIINVYNHITGKTEKMDMENYLCGVLAGEM
                     SSEFDIEALKAQSVAARTYVVYKQEHGKSSKHKNAVVCTDYKHCQEYKSYDTLKKLNG
                     EEWIKNKYSKIQEAVRGTKGQIITYNDKAILPLYFSTSSGKTENSEEVFSAKYPYLKS
                     VESPYDKYSPKFASTLKISNTDFVKSLRRAYSTIVIDVNNLSKQVSITKRSDAGTVEK
                     IKLGNKELTGKDIRTVFKLNSANFDIKFGEGYIDFVVKGYGHGVGMSQWGAEGMAEEG
                     YKYYDILSHYYTDTKIKDIY"
     gene            18433..19101
                     /locus_tag="PC494_001213"
     CDS             18433..19101
                     /locus_tag="PC494_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M23 family metallopeptidase"
                     /protein_id="HDF3911721.1"
                     /translation="MKKKLLEKDGFYLSLFVCVCLLAVGGVWFTNNNVDKLASNKGIM
                     ENANKDSEEEIHLIEKDKKDAIPTATDSKQNLEKAKSKEENKSSTTKLNYIGDKVIRG
                     YSEKEPSYSKTLDVWETHKGVDISCTKGKEVKSLLNGIVVDVFDDEEYGQSVKIKSDN
                     NIVVVYSNLDKNVSVKKEQKVTEGQSLGTVGSTSQIESEEGIHVHLEAYSGEKSIDPM
                     SLIK"
     gene            19199..19459
                     /gene="spoIIID"
                     /locus_tag="PC494_001214"
     CDS             19199..19459
                     /gene="spoIIID"
                     /locus_tag="PC494_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation transcriptional regulator SpoIIID"
                     /protein_id="HDF3911722.1"
                     /translation="MRSHIEERAIVVAKYILEKNTTVRQTAKTFGVSKSTIHKDVTER
                     LKEINPSLAKEVKNVLDKNKSERHIRGGLATKLKYEKEHKKM"
     gene            19656..20675
                     /locus_tag="PC494_001215"
     CDS             19656..20675
                     /locus_tag="PC494_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein"
                     /protein_id="HDF3911723.1"
                     /translation="MAGADIGIDLGTANVLVYVSGKGIVLEEPSVVAIDKRTDSVLAV
                     GEEAKKMIGRTPGNIVAIRPLRDGVISDYDVTEKMLKSFIDKIVDKKGFGRFFMPRIM
                     VCVPTGVTEVEKRAVEDATRQAGAREVYIIEEPIAAAIGAGVDISQPNGNMIIDIGGG
                     TVDIAVISLGGAVVSESIKVGGDRFDDAIVKYMKKQHNLLIGERTAEKIKFEIGSAFK
                     REEEKYMKITGRNLITGLPSSITINSTEMLEALRECVEQIVVATHAVLEKTPPELAAD
                     IGDVGIIMTGGGSLLYGLDKIIEQRTGITVTIADEPLSCVAKGTGIALGSIDLLETGG
                     SFKRK"
     gene            20691..21119
                     /gene="fabZ"
                     /locus_tag="PC494_001216"
     CDS             20691..21119
                     /gene="fabZ"
                     /locus_tag="PC494_001216"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HDF3911724.1"
                     /translation="MLNIDEIKKLIPHRYPFLLVDKITELEVGKRAVGIKNVTVNEPF
                     FQGHFPEYPLMPGVLIVEALAQVCGVAMMSVEENKGKLGVFAGIDKVRIKREVRPGDT
                     LTMEVEMTTLRKNIAKADAKAYVGEELVCKGELMFALVEK"
     gene            complement(21230..21739)
                     /gene="yyaC"
                     /locus_tag="PC494_001217"
     CDS             complement(21230..21739)
                     /gene="yyaC"
                     /locus_tag="PC494_001217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore protease YyaC"
                     /protein_id="HDF3911725.1"
                     /translation="MYLAKVNYSDDDVIQMLSSVLKTIINENTIVVCIGTDRAIGDTL
                     GPLVGTILKNSNFKYPVYGTLDNPIHALNIYESLDTIKNTHIQGNFLAIDACLGSQSN
                     IGNIQIREGPILPGKGVGKKLPQIGNYSIVGIVDKIDENNKLSFNNIRLSFILDLAET
                     IALALLVST"
     regulatory      21928..22031
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00162"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="SAM riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF00162"
     gene            22168..23361
                     /locus_tag="PC494_001218"
     CDS             22168..23361
                     /locus_tag="PC494_001218"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HDF3911726.1"
                     /translation="MARHLFTSESVTEGHPDKICDQISDSILDALLEKDPQSRVACET
                     TVTTGLVLVAGEISTSAYVDIPKLVRETVREIGYTRAKYGFDCDTCAVITSIDEQSGD
                     IAMGVDEGLESKTGEEIEEEIEKVGAGDQGIMFGFACNETPELMPLPISLAHKLSRRL
                     TEVRKTGLVDYLRPDGKTQVTVEYEGSKAVRVHTVLISAQHCETVSNDKIREDLINHV
                     IKEVIPAELLDEETKIYINPTGRFVIGGPQGDTGLTGRKIIIDTYGGYSRHGGGAFSG
                     KDPTKVDRSAAYAARYVAKNIVAAGLADKCEIELAYAIGIARPLSIFIDTFGTGKVSE
                     EKLVELVNKHFDLRPGAIIRDLDLRKPLYKKVAAYGHFGRTDIDLPWERTDKVEQLRK
                     DALGE"
     gene            23677..24774
                     /locus_tag="PC494_001219"
     CDS             23677..24774
                     /locus_tag="PC494_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3911727.1"
                     /translation="MSGKVNIKTVISFAGAYVATVIGSGFATGQEILQFFTFYGYAGI
                     IGGIISMVLFSWFGAEVIDKGRELKLKEPIKIYQVYCGKYLGTFFEWFGPLFLFGTLV
                     IMIAGAGATLSEYYGLNPYVGRIGMAIVSLITVSLGLTRLSKILGNIGPIIIIFTLLV
                     GAISLFSNIDALSNAGNMVDSLNIKTATSNGYFSGVLYTCYNVIIVITFLTGMGASAV
                     NKKDAVWGGIVGGVALMAAAIMMNLALLSDIGNIYTKEIPALYLADKISPIIGILFSV
                     VLLLGIYTTAVPLLWSVTNRFVEDDHPKFKIITIVVSILACIGGLLPFDKLVGTLYPY
                     TGYMGILILLCMLYRRITKTEGYKENKSEIS"
     gene            25038..27257
                     /locus_tag="PC494_001220"
     CDS             25038..27257
                     /locus_tag="PC494_001220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HDF3911728.1"
                     /translation="MEKLEGMISEIVFKNEDNGYTIAHLVNENDEIVVVGCMPTLAIG
                     ESIEVEGKWVNHKIYGTQFEVNSFMPVTPSSLEGIYVYLSSGMIHGIGEKMAKRIIDK
                     FGVDTLEVIQNSPEKLQEVEGIGSKKVKQIVKSYEEDRELRNIIIQLSPFGITPNYCL
                     KIYKKYKSSAIEVINKNPYQLAEDIRGIGFKVADSIASKIGIDKNSKDRICQGILYTL
                     NKSLSNGHTYLPEHVLIQDSEKLLELNGEIIKECVMMLVYNQKIHIEKVNNENLIYLM
                     PYYLAENGVCSQIVKLSQYEFEDLKIDIDNEINVLEEDKKIKLAEKQILAVKESVNSG
                     VLIITGGPGTGKTTTINAIIDIFENNGKSVTLAAPTGRAAKRMSETSNKEAKTIHRLL
                     EMGFSTDDDLTFFKDEEDPINSDVIIVDEVSMVDIILMYNLLRAIKLGTRVILVGDSD
                     QLPSVGAGNVLKDMINSNIINVVKLNEIFRQAQESMIIVNAHKINNGEPLYLNTKGKD
                     FFFIRKSTNEEILNEIIGLVNERLPKFYKVDKLKDIQVLSSMRKGELGVTNLNIELQK
                     YLNKKEKFKVEESFSKRLFRVGDKVMQVKNNYTKKWETEDQKESGEGIYNGDIGYVYH
                     IDKDKKTIYILFDQTKIVSYLYDELDEIDHSFCTTIHKSQGSEFPVVVLPIAWAPPML
                     LSRNLLYTAVTRAKKLVVLVGDVKYLEYMIKNNRVNQRYSNLGYKLNKFKQEGLLIE"
     gene            27260..28042
                     /locus_tag="PC494_001221"
     CDS             27260..28042
                     /locus_tag="PC494_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HDF3911729.1"
                     /translation="MKICNDNFIKNFKNMINKCLDFIYPENISCIICDKSIKKTNTYS
                     ICKSCFKEMNFIQDGCMKCGKPIICHSIEKEFIEECSYCFNKDFYFDKSISCIEYNDV
                     TKKMVLGLKYNQKTFMAKYIAQIMKEKLYLENIKFDYILFVPLHKKRLNKRGFNQAQK
                     IAFNLSKIVNIPLLDCISRKKYTRMLYKLNKKERKEELKNVFVVKENVKLINNKNILL
                     IDDIFTTGLTTNEISKLLKLSGANKVFVLTLLTKANDNYIME"
     gene            28374..30287
                     /locus_tag="PC494_001222"
     CDS             28374..30287
                     /locus_tag="PC494_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HDF3911730.1"
                     /translation="MICLNKRQENLLTTLLLKEEFINVNKIANDFECSERTIRNDCKY
                     IDEWLSTFCNAYIKRKPNIGIKFSGDGTDKILVNQKLRGEVKRVNSELHKQVEILNLL
                     LCNNKKVTLNDLSNKLYINKNIVREEISKLSVALNNYNLNISTKKGSGIYIEGDEKDI
                     RIMLVSFLFKYIDKYRLNIDEIEYFHIVDIIIVKNIMLTIEEDMDIRLTDISFKQLML
                     FLLINIIRIRLGNSLKVSNTKKELKLKMLILDIEDELKSNLSIVLNYEEKLFIESLIL
                     GMNKQINSNNIKKSLYLNEELASYTKKIINLVSEESGINFNNDILLYEQLICHLNVTM
                     HQMKSNVYLENPLLDNIKTKFCFLFTVISSSIEIELKGKQITEDEIGYLTLHFQTSLE
                     RKYSKRESNKKASIVCPFSFGVSMLLKVKIEKRFDNIKIIETLREEDLKRDNFNKTID
                     FIIAFQEYENIQKPIFITTPLFTDEDENKLKEFTNKIKEKDTSYKLMNRLMMSDYLIR
                     ELEHDDIYEAITYLTNLLIEKHYAEKEYLQSIITREKSYPTNVGKGILFPHGDMKYIK
                     QSVLCFARLKTPIKIRNGKDIKIILLLAYKKDDDRKVFRELFKEISNLTEDENMLDIL
                     SKCDIEKVKDILI"
     gene            30428..30736
                     /locus_tag="PC494_001223"
     CDS             30428..30736
                     /locus_tag="PC494_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HDF3911731.1"
                     /translation="MEEIVLKIIIHAGNAKSMLYEALDYAKENDFKKADELIENANEE
                     ILKAHKVQTELIQKEAGGDKSDISILLIHSQDHLMTCMSERNLIKEMIMLRKEIQKLK
                     "
     gene            30759..31085
                     /locus_tag="PC494_001224"
     CDS             30759..31085
                     /locus_tag="PC494_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDF3911732.1"
                     /translation="MKRKVYLFCSFGMSTSLLADKMQKVADEHNLPIEVEAFPIAEID
                     KIVEEKNPDCILLGPQVKYMLKELKPKFEAQGKLIDIINEVDYGTMNGEKVLKLAIKL
                     IKSKQA"
     gene            31124..32458
                     /gene="celB"
                     /locus_tag="PC494_001225"
     CDS             31124..32458
                     /gene="celB"
                     /locus_tag="PC494_001225"
                     /EC_number="2.7.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HDF3911733.1"
                     /translation="MNRLERILMPLAEKIGKNKLLIAIRDGFLVSSPLLIIGSLFLLV
                     ANFPIKGWNEFVGQIFGPDWAVKLQQPTVATFEVMTLLAVLGIGYSYAKQIDVDPIAS
                     AAVAIVAFFIITPFVIPYTPEGTESVYMVTGIPLGWMGSKGMFVGMITAITSVKLFAA
                     VVKKGWTLKMPDGVPPTVSKSFAALIPSAIVMVVFFLVKIAFEATPYGSIHEFIFKFL
                     QMPLLKLGNSLGAMAIAYIFLHLFWFFGINGSSVVGAVYNPILKILSAENLAAFQAGS
                     KIPNIITGQFQDMFATFGGAGSTLSLVIAMLLICKSKRIKSMGKLSILPGIFGINEPL
                     IFGLPIMLNPILLIPFAIVPTINIIIAYFCMSAGLVPLTNGVQLPWTTPIIFSGFLTT
                     GWQGAVLQLVLLILGIFMYIPFIKMLDKQYLREENETVEEEDDDISFDDLVL"
     gene            32469..32990
                     /locus_tag="PC494_001226"
     CDS             32469..32990
                     /locus_tag="PC494_001226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine/betaine/sarcosine/D-proline family
                     reductase selenoprotein B"
                     /protein_id="HDF3911734.1"
                     /translation="MKKIVMILDQIQAGAGGKEKSNIPPAGKSSPLGPGVMMEQFLNE
                     SKVIATLFCGDEFFVNNQEEVTSKMIAMVKKLNPDVVICGPSFNYENFSKMSAILSKN
                     INDKTDIPAFAAMSEENIDVINEYKNDICIVKTPKKGGIGLNDSLNNICKLAKAIANK
                     EDITLMKEEFCYQ"
     gene            33083..34042
                     /locus_tag="PC494_001227"
     CDS             33083..34042
                     /locus_tag="PC494_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase"
                     /protein_id="HDF3911735.1"
                     /translation="MWGMIATWRMALEGITEASEHLEKGMEAGDAVELAVRRVEDYPF
                     YKSVGYGGLPNENCEVELDAAFMDGNTLDIGAVAGIRDYSNPVSIARKLSYEKVNNFL
                     VGIGAEDYAHKNGFERKNMLTDRAKLHYKKRKKETLDKGLSPYAGHDTVGMISLDKTG
                     KMCAATSTSGLFMKKRGRIGDSALSGSGFYVDSSIGGATATGLGEDLMKGCISYEIVR
                     LMKEGKHPQEACDIAVNELDKQLIERRGKAGDLSLVAMNNKGEWGVATNIADFTFSVV
                     TKEESPTVYISNRVDGKTIHKVISNEWMEAYEARIKAPIEVSE"
     gene            34091..35143
                     /locus_tag="PC494_001228"
     CDS             34091..35143
                     /locus_tag="PC494_001228"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Sapep family Mn(2+)-dependent dipeptidase"
                     /protein_id="HDF3911736.1"
                     /translation="MNIISNKIDELKEDLLSDIIDIVKIPSVKGESENGFPFGEKVGE
                     ALNKALEISEKLGFKVRNLDNYIGYAEHGDSDDYVCVIGHVDVVHEGDGWKHQPYKGE
                     ETNGRIYGRGVLDNKGPIMSALYGLYAIKELNLKLDKRVRIIFGTNEESGFEDIPYYL
                     EKEKAPIMGFTPDCKYPVVYGEKGMAKIRIKSKINYEEDVYLGFIENMSENVLVTYKE
                     LNIENSDTILDIKVKYDFSYKLKDVLDEIKASFPNSIDIEVISNFNPVYFDKESNLVK
                     KLQLAYERVTSLDGTPVTTNGGTYAKVMPNIVPFGPSFPGQKGIAHNPDEYMDIEDII
                     LNAKIFANAIYELAKE"
     gene            35146..35820
                     /locus_tag="PC494_001229"
     CDS             35146..35820
                     /locus_tag="PC494_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HDF3911737.1"
                     /translation="MLEIIGMSVEDAKIIEDCGADRIELVSALTEGGLTPSFGLIESV
                     VNSVKIPVNVMIRHHAKSFVYSKEDISIMQKDIGVVKEIGANGVVFGVLDKNNNIDEK
                     NLNVLLKCCDNLDVTFHRAIDESNTIDSVKILKDYDKITNILTSGGKGSIVDNIQMIK
                     NMMLSSNHIKILLGGGLNFNNIEKIKELTKASNFHFGTAIRINNSPFEDIDRQKLKQL
                     VNIISR"
     gene            36373..36924
                     /gene="raiA"
                     /locus_tag="PC494_001230"
     CDS             36373..36924
                     /gene="raiA"
                     /locus_tag="PC494_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HDF3911738.1"
                     /translation="MNIIISGKQIELTDAIKNKIETKLSKLDNYIHPDTDVKVTVSAR
                     KARQKIEVTIATVNGPIIRAEDMQENLYTAIDVVYDKLSKQLKKYKKRLQDKHKDNKS
                     IRFQDAEINLADEQEDYGDENQELVIQRRKKFSVKPMSEEEAVLQMELIGHDFYMFKN
                     IDSDEIAVVYKRNNGGYGIIEHE"
     gene            37056..39731
                     /gene="secA"
                     /locus_tag="PC494_001231"
     CDS             37056..39731
                     /gene="secA"
                     /locus_tag="PC494_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HDF3911739.1"
                     /translation="MSFMDNLFNMADKKELKKFNKTVDIIDSLEPKFESMADSELKNM
                     TNIFKERLANGESIDDILPEAFAVVREVSKRVLGLRHYRVQMIGGIVLHQGRIAEMKT
                     GEGKTLVATAPVYLNALTGKGVHVVTVNDYLAKRDRDQMAKIYEFLGMSVGVIIHGQN
                     PKVRKEQYDCDITYGTNNEYGFDYLKDNMVIHKEQRVQRGLNYAIVDEVDSILIDEAR
                     TPLIISGPGDKSTHLYSDANTFVLTLKPDDYELEEKDKAVSLTASGIQKAEVYFNVDN
                     ITDISHTELYHHINQALRAHVIMKKDVDYVAKDGEIVIVDEFTGRLMFGRRYSEGLHQ
                     AIEAKEGLKIQRESKTLATVTFQNYFRMYKKLSGMTGTAKTEEEEFKAIYKMDVFQVP
                     TNKLMIREDLPDCVYKSEIGKFNAVAQEIIERHKVNQPILVGTVSIEKSELLSQILKK
                     KGIKHEVLNAKHHDKEAEIIAQAGRLGAVTIATNMAGRGTDIVLGGNPDFLTKREMRR
                     NGFKEEIVNRVDTPIEGIPVKGNEILFEAREEYEKLFEKFKQQTQEEQKQVVEAGGLA
                     IIGTERHESRRIDNQLRGRAGRQGDPGSSRFYIGLDDDLMRLFGSDRISGIVDKIGLE
                     EDMPIEHRILSKSIEGAQKKVEGKNFGIRKHVLQYDDVMNKQREIIYAERKRVLEGED
                     LQEQIQSMTHSIIEEAVTLYTQDKGFDEEGFKEHMYNLFLPKGSIEIPEIEKLNPVEI
                     TEKVYEIAMKIYTSKEEQVGYERMREVERVILLQAVDNHWIDHIDAMDQLRQGIGLRA
                     VGQQDPVIAYKMEGFDMFDEMNKHIKEDTVRYLFNITIETPVERKAVVDVENLSSPSD
                     GTLPTSKTVKKDEKVGRNDLCPCGSGKKYKNCCGR"
     gene            39746..40853
                     /gene="prfB"
                     /locus_tag="PC494_001232"
     CDS             join(39746..39820,39822..40853)
                     /gene="prfB"
                     /locus_tag="PC494_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_153309863.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HDF3911740.1"
                     /translation="MLKLQEYRHSMEQMASNLEELRVSLDIASLMKNIQINEEKMNQQ
                     DFWNDNEVAQRVLQENKSLKETLEEYESLKSLLEDIEVLIEIGLEEDNDSVERDIEKS
                     IESMEEKLSEMKIKTLLNGEYDKNNAILSINAGTGGLDAQDWAQMLLRMYIRWSESKG
                     YKVKLLDIISDPEAGIKTATILVEGTNAYGYLKSEKGVHRLVRISPFDPSGKRHTSFA
                     SIDVTPELDENIEVEINPSDLKIDTYRASGAGGQHVNTTDSAVRITHIPTGVVVQCQN
                     ERSQHLNKDRAMRLLMAKLIELKELEQKEKIEDIQGKYSQITWGSQIRSYVFQPYKLV
                     KDHRTNAEFGNVDSVMNGNIDLFINEYLKMNKIV"
     gene            40997..43138
                     /locus_tag="PC494_001233"
     CDS             40997..43138
                     /locus_tag="PC494_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011010799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HDF3911741.1"
                     /translation="MDINQILKKEFNLRDEQINNTLKLIDEGNTIPFIARYRKEMTGE
                     MSDVTLREFYEKLMYLRNLQSRKDDVVRLIDEQGKLTDEITQNIEKAKTLQEVEDIYA
                     PYKQKKRTRATIAKEKGLENLALSILENNLDNIEIEAKNYLDEEKEVLSIEDALKGAR
                     DIIAELVSDDAKIRKYIRELALREGMIVSKSATDEKSVYDMYYDYSEAVKSMAPHRVL
                     AINRGEKESFLKVKLEINNDKVLNYIINEYVNDKNFKNKEEIVSSIEDSYKRLIFPSI
                     EREIRNHLTEIAQERAISVFGKNVKSLLLQPPVKDKVVMGFDPAFRTGCKIAVVDKNG
                     KLLDYTTVYPTDPQNDVEGAKKVLKGLIEKYDIDIISIGNGTASRESETFVSEMIKEI
                     DSEVQYVIVSEAGASVYSASELANEEHPDINVSIRGAISIARRLQDPLAELVKIDPKS
                     IGVGQYQHDLNKKRLEEVLDGVVEDSVNSVGVDLNTASYSLLEHVAGISKAIAKNIIA
                     YREENGDFTSRAQLKKVKRLGPQAFTQCAGFMRILEGKNPLDNTGVHPESYDICKKMI
                     EIIGYSLDDVKNKNIGEIDEKIKEIGLRELSEKLEVGQVTLKDIIAEIKKPGRDPREE
                     GIKPILRTDVLKIEDIQEGMTLKGTIRNVVDFGAFVDIGIKNDGLVHKSEMSNSFVKD
                     PMSIVTVGDIVDVKVIGIDLNKKRVALSMKK"
     gene            43286..44452
                     /locus_tag="PC494_001234"
     CDS             43286..44452
                     /locus_tag="PC494_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HDF3911742.1"
                     /translation="MIFIKNGKINTITNGIIHGDILIDEGKIIEIGEDLIAPLDVEVI
                     DASNKLVFPGFIDAHTHLGLWEDGIGFEGADGNEETDPITPQLNPIDGINPMDRTFKE
                     AFEGGITSVCTTPGSANVMGGQCIAIKTCGKRIDKMVIKNPVASKIAFGENPKSCYGQ
                     DDKSPQTRMAIAALLRENLKKAEEYLEDIDMYESHDDEDCEKPEYDIKMESLIPVLRR
                     EIPFKAHAHRADDMFTAIRIAKEFNLKLTLDHCTEGHLIVDELVEEGFPVIVGPSLSE
                     RSKFELRNLTFNTAGILSNAGLDVCIMTDHPVIPVQYLPICAGIAVKHGMKEEKAIES
                     ITINPAKALGIEDRVGSIEVGKDADLVIWDNSPLEIQSNVLYTIINGKVVYEKK"
     regulatory      44512..44629
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            44754..45359
                     /locus_tag="PC494_001235"
     CDS             44754..45359
                     /locus_tag="PC494_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HDF3911743.1"
                     /translation="MQNTAKRGNMISTRTLVVMSILSAISYLLMFIQAPIPGIFPDFL
                     KIDLSDIPAIFGGMSLGPLVGFGIVVVKNVLQAITATTTGGIGEFANILIGGSYVMIL
                     CYSYKRSGDLKGVLIGFVLGTISMTIIGSLVNYFVMLPLYGQLMGLDAIIGLGSAINP
                     QVHDLFTFVIWMIAPFNVLKAVIISLVTLPLYKKMGNIIKK"
     gene            45688..46728
                     /locus_tag="PC494_001236"
     CDS             45688..46728
                     /locus_tag="PC494_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4116 domain-containing protein"
                     /protein_id="HDF3911744.1"
                     /translation="MHLSKKIKKLFLDDKGYYFNSNWKDIHIGIYDTKLGDSLKYITN
                     EYIENMERVKYDYRELKNIENQTDGMCILAIRQNYKALEYVKNQTEELCLEAIKYNYK
                     ALEYVKEQTEYLCLEAIKKDCNALKYVRNKTEGLIIKAISHSSNIDVVSILKALETQT
                     RRICLEAIKKDGRCLAYVREQSEELCIEAIKQNYKALKYVKNQTEKMCIESVRQNGMA
                     LQYVNKQTDKICIEAVKQDGRSLQFVNNKTEEICINAIRYLNKKYNIKDVLSYIDKYT
                     EDICIEIVRQNGKMLMYIKNQTEKMCIEAVKENYKSLKYVKEQSERICKEALKQNHKA
                     KEYVKIAIDDCI"
     gene            46867..47319
                     /gene="tsaE"
                     /locus_tag="PC494_001237"
     CDS             46867..47319
                     /gene="tsaE"
                     /locus_tag="PC494_001237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HDF3911745.1"
                     /translation="MAKIYLENENKTREIGYKLGKLLKEGSVICLVGDLGAGKTTMTQ
                     SLADSLGIEDYITSPTFTIINEYEGKIPLYHFDVYRIGSSDEMYDIGYDEYVNSNGIC
                     IIEWANLIEDILPKEYLNIELRYKDEGREMILTPKGEFYKEIVEELIK"
     gene            47319..48035
                     /gene="tsaB"
                     /locus_tag="PC494_001238"
     CDS             47319..48035
                     /gene="tsaB"
                     /locus_tag="PC494_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HDF3911746.1"
                     /translation="MKILGMDTSSMAASVAVVEDDNLICEFTVNNKKTHSQKLMPMIE
                     NMLSMSDLSIKDMDLLAVCIGPGSFTGLRIGMATVKAMAHVNNIPIIAVNSLESLANN
                     INFCDRKICCILDAQKNQVYSAKYKFENGEMIELDGVDVVEFDALVDEIVSTNEEFII
                     VGEAVYKYKDKLENIKNIKIPSPANNVSNAGSLCSLALNKYNKNIDVHTCYTINPMYI
                     RKSQAEVQYDEKMKRLNNGR"
     gene            48025..48501
                     /gene="rimI"
                     /locus_tag="PC494_001239"
     CDS             48025..48501
                     /gene="rimI"
                     /locus_tag="PC494_001239"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HDF3911747.1"
                     /translation="MEDNTKLIVDDIKIEEMTTEDIDEVFEVEKNCFEDYWSKESFRK
                     ELSNEVARYIVAKLNGKIVGYVGIWLILDEGHINNVAVHSDYRGKKIGDKLIKGIVDL
                     CKDNNIASMTLEVRASNKIAQNLYRKYGFKMGGIRKEYYSDNKEDAIIMWNQLKEV"
     gene            48507..49523
                     /gene="tsaD"
                     /locus_tag="PC494_001240"
     CDS             48507..49523
                     /gene="tsaD"
                     /locus_tag="PC494_001240"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HDF3911748.1"
                     /translation="MSDIITLAIESSCDETAASVLKNGREVLSNIISTQIETHKKFGG
                     VVPEVASRKHVENIDIVVQEALDKANIGFNDIDHIAVTYGPGLVGALLVGLSYAKALA
                     YTLNIPLVGVNHIEGHLSANYIEHKDLKPPFITLIVSGGHTHLVEVKDYGKYEILGKT
                     RDDASGEAFDKISRAMNLGYPGGPIIDNLAKNGNKHAIEFPRAYLEEDSYDFSFSGLK
                     SSVLNYLNGKRMKNEEIVVEDVAASFQEAVVEVLSTKALKAVKDKGYNIITLSGGVAS
                     NSGLRAKITELAKDNGITVKYPPLILCTDNAAMIGCAGYYNFINGKTHDMSLNAVPNL
                     KINQ"
     gene            49820..52528
                     /gene="hpdB"
                     /locus_tag="PC494_001241"
     CDS             49820..52528
                     /gene="hpdB"
                     /locus_tag="PC494_001241"
                     /EC_number="4.1.1.83"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxyphenylacetate decarboxylase large
                     subunit"
                     /protein_id="HDF3911749.1"
                     /translation="MSQSKEDKIRSILEAKNIKSNFQNKENLSEFNEKKASKRAEDLL
                     DVYYNTLSTADMEFPYWYNREYRKSDGDIPVVRRAKALKAAFSHMTPNIIPGEKIVMQ
                     KTRHYRGSFPMPWVSESFFVAQGEQMREEAKKLASNTADELTKFGSGGGNVTESFGNV
                     VSIAGKFGMRKEEVPVLVKMAKEWVGKSVEDLGFHYEKMMPDYDLKENLMSTLICMFD
                     SGYTLPQGREVINYFYPLNYGLDGIIEMAKECKKAVAGNASGDGLIGMDRLYFYEAVI
                     QVIEGLQTWILNYAKHAKYLESIETDLEAKKEYSDLVQILEHIAHKQPRTFREALQLT
                     YTIHIASVNEDAISGMSIGRFGQILYPWYEQDIEKGLITKEEVIELLELYRIKITCID
                     CFASAGVNGGVLSGNTFNTLSIGGLKEDGSTGANELEELLLEASMRCRTPQPSLTMLY
                     DEKLPEDFLMKAAECTKLGSGYPAWVNNSNGTTFMMKQFADEGMTVEEARAFALGGCL
                     ETSPGCWKQLTLNGKTYSIAGGAGQSAGSGVHFIANPKILELVLMNGKDYRMNIQVFE
                     PHNKPLDTYEEVIEVFKDYYKQAINVLERANNIELDIWRKFDTSIINSLLKPDCLDKG
                     QHIGNMGYRYNATLNVETCGTVTMVNSFAALKKLVYDDKAFTIEEMKDAILNNFGFKD
                     ALEVGNYSMADQVKVDKTGKYDAIYKACLDAPKYGNNDLYADNILKNYEVWLSKVCEE
                     AQSLYAKKMYPCQISVSTHGPQGAATLATPDGRLSGTTYSDGSVSAYAGTDKNGVYAL
                     FESATIWDQAVVQNSQMNLKLHPTTIKGQQGTKKLLDLTRSYLRKGGFHIQYNVVDSE
                     TLKDAQKNPDNYRQLMVRVAGFTQYWCELGKPIQDEVIARTEYEGV"
     gene            52532..52789
                     /gene="hpdC"
                     /locus_tag="PC494_001242"
     CDS             52532..52789
                     /gene="hpdC"
                     /locus_tag="PC494_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxyphenylacetate decarboxylase small
                     subunit"
                     /protein_id="HDF3911750.1"
                     /translation="MRKHSDCMNFCAVDATKGICRLSKQMINLDDAACPEIKVMPKCK
                     NCKNFVEANDEGIGKCVGLEKEDWVYSTLNAITCEGHVFNE"
     gene            52782..53732
                     /gene="hpdA"
                     /locus_tag="PC494_001243"
     CDS             52782..53732
                     /gene="hpdA"
                     /locus_tag="PC494_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxyphenylacetate decarboxylase activase"
                     /protein_id="HDF3911751.1"
                     /translation="MSSQKQLEGMIFDVQSFSVHDGPGCRTTVFLNGCPLSCKWCANP
                     ESWTVRPHMMFSELSCQYENGCTVCHGKCKNGALSFNLDNKPVIDWNICKDCESFECV
                     NSCYYNAFKLCAKPYTVDELVQVIKRDSNNWRSNGGVTFSGGEPLLQHEFLHEVLLKC
                     HEVNIHTAIETSACVSNEVFNKIFNDIDFAFIDIKHMDREKHKEQTGVYNDLILENIS
                     NLANSDWNGRLVLRVPVISGFNDSDENISDIISFMHKNNLVEINLLPFHRLGESKWIQ
                     LGKEYEYSDKGDVDEGHLEELQDIFLDNGIACYVGHETAF"
     gene            54047..55009
                     /locus_tag="PC494_001244"
     CDS             54047..55009
                     /locus_tag="PC494_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HDF3911752.1"
                     /translation="MNKSWSNLIIKNKDRKVRSGWIIIAVMATFYILQYYLSMILVEI
                     IRKILVATGDINLKTNYFSEYANWLNDVGLQIVFQILTDSLMIIIPIIVWRFIMKNPI
                     SEMGLHSYRIKKKEGYVGMLLGIFNCTVIFIITITIGGGHVTSWVPKISPLTVSWILV
                     FILVAFAEEILNRGFFMAVLRRCKNIYFIMIVPSVIFGLIHIWNPDVTFLSVINIIII
                     GILFSYMFIKSSNIWMCIGYHFAWNVFQGIIYGMPVSGLQVPGIITTQITHGNLLNGG
                     MFGIEGGILTTFVNLLSFIFVWYYYRDSKYDFVSDKVNVTNIKN"
     gene            complement(55108..56088)
                     /locus_tag="PC494_001245"
     CDS             complement(55108..56088)
                     /locus_tag="PC494_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HDF3911753.1"
                     /translation="MNLKLIWINILNPVFIKNEIKRKKIQIIIFFFINFGLTYSLGLL
                     LYYNKFIDPENFASFMMILPLSSVAIAKFYTEGLNNDMYEFYSLIILFFLIYSLLIVL
                     KLLNLINNNEFIIINLILTFISSLSIIIYSSNKKNLYPVKNIKLGSLLIIYFMISVIV
                     PTSFILILQGAQPNYSGIIKFIFTPITSLTTIYIFFSEEYAWRGFLQNIFFDKFGKKL
                     GVIILGMCWSLWHLPLIFTLYTPEAPILGIILRSIHIVGISIFLGYLYIKTKNIWFCA
                     IIHVLNNSAFLITNSKESTITYHDILIVSMVVLIFYVPFLFTKEYKNNLE"
BASE COUNT        22490 a         6055 c        10629 g        16928 t
ORIGIN      
        1 aaatgttcca aggtagctca acggtggagc aaccggctgt taaccggtag gctgtgggtt
       61 cgagccccac ccttggagcc aaaaaagccg aagtggcgga actggcagac gcacaggact
      121 taaaatcctg cgggacttac ctctcgtacc ggttcgattc cggtcttcgg cacttataaa
      181 acaatatcgc ggggtggagc agttggcagc tcgtcgggct cataacccga aggtcgtagg
      241 ttcaagtcct gcctccgcaa ccattaaaac ggctcgttgg tcaagaggtt aagacaccgc
      301 cctttcacgg cggtaacagg ggttcaattc ccctacgagt caccaattca attaaatatg
      361 cgggtgtagc tcaatggtag agttctggcc ttccaagcca gctgtgaggg ttcgatcccc
      421 ttcacccgct ccaaaaatgg gaccatagct cagctgggag agcacctgcc ttacaagcag
      481 ggggtcacag gttcgagccc tgttggtccc accattcgcg gcctggtagt tcagttggtt
      541 agaatgccag cctgtcacgc tggaggtcga gggttcgagc cccttccagg tcgccaaatt
      601 aaataagcgg gaatagttca gtggtagagc gcaaccttgc caaggttgaa gtcgcgagtt
      661 cgaatctcgt ttcccgctcc ataataactt gggtgcatag ctcagctgga tagagcaacg
      721 cccttctaag gcgtgtgtcc ggggttcgaa tccctgtgcg ctcattaaga aaagtttact
      781 ataaattata gtaaactttt atattgttta aaaagacaca ggaaacatgt atattacctg
      841 tgtcttttta tttataaact ttaaactatg taaaaattac agtatattct aatagagtta
      901 cagtatattc attaatattg taaacatacg gagggtaatg tataatagtc tacaagatgt
      961 ttatgaaggc atcagttaaa tataataaat ataactaatt agtaagagtt atatacatta
     1021 tattgtatac tttatggtat ttatatattg aaataactta tgaaattatt tataaagaga
     1081 ttcatgagca tatttttgtc taaacaataa gtataagaaa ttataaaaaa ttagagacta
     1141 tagtgaattt acaatttaat gtaatattta taagttatac taaataaatt attatactgt
     1201 gaaatggata tataacttta ggtattgtgt attattttca ctgtaggaga ttatatctag
     1261 ttatacataa taagttttaa tgatagttta tagtaagata ttaaaataaa tttatctaat
     1321 ctagatatga aataagttat tactttaata taaaaatgaa tctaatggaa taatattgat
     1381 gataagtaat atttagattt tgtatttgtt tatagttaat aagtggatta tagaatttat
     1441 aataattaat atatattaaa caaagatata ttaagatatt ttagaacata aaactgaatt
     1501 aaggcgcgag tactattttg tattcgcgcc ttgatggttt gagttatttg agtaaaaact
     1561 aactttaata agaaatatgt atttattaag ttgatatttt taatgtgttt agagattatt
     1621 taacaatctc caaatataaa actagaatta tttacataaa agttaaatag tttgtataga
     1681 gttagattta tatagtataa tacttagtgt aaataattaa gaagttatca aacaggagga
     1741 taaaactgtg ttagatataa attctttttt aaatggattt tttaatataa tattaagaat
     1801 gagtatatat gatttaattg acatatctat agtagcgtat attttttaca aaatatttat
     1861 gtttataaaa gatacaagag cagaacaagt gtttaaaggt ataatatttc ttttattagc
     1921 aactcaactt agtaacacct ttaaattgca taccgtttat tggatatctc ttaaagcttt
     1981 agattatgga gttatagctg ctcttataat ttttcaacca gaatttagag caggacttga
     2041 acatatagga agagcaaagt ttaatttatt tggaaagaat gtaaatactt ctgaagaaac
     2101 tctcaataga aatatagaag aaattgtaga agctttatat tcactttcta gacaaaaaat
     2161 aggagctctt atcataatgg agagagaaac tagaataagt gatataataa atacaggaac
     2221 tattattgat gctgaaattt ctaggcaact attaataaat atatttatac caaatacacc
     2281 attacacgat ggagctgttg taattagaga ttctaaggta aaagcagctg catgtttttt
     2341 gccattgaca gaaagtaagg atttaagtaa agatttgggc actagacata gagcaggaat
     2401 aggggtaagt gaggtgtctg actgtataac tctgattgta tcagaggaaa caggtggcgt
     2461 atcaattgct aaagcaggta agttatatag agatatttct agagaaagaa tgatgaatat
     2521 attacgtagt aatttaaaaa caaatacaga aacaagaagt tttttcaaag gtggtatatt
     2581 taaatgataa atagactaaa aaataatacc aaaataaaaa taatatcatt tttaagtgca
     2641 attgcattat ggatgtatgt tatggctgta gttgaccctg aagaaactaa agggtttgaa
     2701 gatatacctg tatctataag taatatgagt gatttaaagg ataaaaatct tgttatatat
     2761 ccagacgaaa aattaacagc agatgtatat ataaaaggta gtttatcaaa ggtacaaagt
     2821 gttaaaaaag aagatataca tgtatatgga accattgaag acccaataca aggacagaag
     2881 gaagtatatt taaaagcaaa tattcctcaa ggtgttactc tagaatttaa gcatgatgtt
     2941 ttagtagtaa atcttgaaaa aaacataaaa gaaaaaagag atataaaggt agaagtaagt
     3001 ggaaattcaa aaagaaatat aaataaaatt gaacttagta aggaatttgt cgatgtatca
     3061 ggtccaagaa ctctagttaa agaagtcaaa agtgtaagag ctaatctaga tgttggtaat
     3121 gagacagatg atttttctaa aaaattgcaa ttaataccat taaatagtga tggaactaag
     3181 gttgaaggag taacattaag ttcatccttt gtgactgcaa agatagagct attgaaggaa
     3241 aaaattgtcc caataagagt aagtctaaat gataataaag ataatgatgt actgaaaaac
     3301 tataaattaa gtaaggaaca agttacaata aaaggaaaga aagatgatat agacaaaata
     3361 agttatatta agacaaaacc tattgactta gctgatttgg ctaatggtga agaaaaagaa
     3421 gttagcttag aaattccaga gggtataact cttgaggata gctctataac aattaaatta
     3481 aatgatacaa aacaattgag tgcagaattt ttatataatg cgggagatat tgaattaaga
     3541 aatatcccaa caaatatgga taatccaaat gtaatttctg atgtagatat aaaagttgtt
     3601 gtagagtcaa cggaggattt gagtaagtta aataaaaaag atatttcatt atatattgat
     3661 ttatcacaag gtcctgagga agatagtaaa tataaaataa aatatgaaac aacatatcaa
     3721 tttaaaaaaa taaatataga acctaatatt gttgaagtgg aatgaacaaa tatttcgaat
     3781 atttagttgt tacaagatgc gacaaaaaaa cctataaaat taagtttgtt aattttatgt
     3841 ttttgttgca tcttgtttat tttagttata ttataaaata aggacaatga gatatttgtt
     3901 aaatctaaaa agcgctagat atatgaaaaa agactgataa atagatttaa ataaatattt
     3961 tgaattaaat atttcaatta tctctaggaa aacgttgctg aacgagttat aatttaattg
     4021 agatataaaa agttctattt caaaaaattc aagatgaggt ggaaatgcat gagaagtttt
     4081 gaagaagtaa ttaagtttgc aaaagaaaga ggacctaaaa ctatatcagt agcatgttgc
     4141 caagataaag aagttttaat ggcagttgaa atggctagaa aagaaaaaat agcaaatgcc
     4201 attttagtag gagatataga aaagactaaa gaaattgcaa aaagcataga catggatatc
     4261 gaaaattatg aactgataga tataaaagat ttagcagaag catctctaaa atctgttgaa
     4321 ttagtttcac aaggaaaagc cgacatggta atgaaaggct tagtagacac atcaataata
     4381 ctaaaagcag ttttaaataa agaagtaggt cttagaactg gaaatgtatt aagtcacgta
     4441 gcagtatttg atgtagaggg atatgataga ttatttttcg taactgacgc agctatgaac
     4501 ttagctcctg atacaaatac taaaaagcaa atcatagaaa atgcttgcac agtagcacat
     4561 tcattagata taagtgaacc aaaagttgct gcaatatgcg caaaagaaaa agtaaatcca
     4621 aaaatgaaag atacagttga agctaaagaa ctagaagaaa tgtatgaaag aggagaaatc
     4681 aaaggttgta tggttggtgg accttttgca attgataatg cagtatcttt agaagcagct
     4741 aaacataaag gtataaatca tcctgtagca ggaagagctg atatattatt agccccagat
     4801 attgaaggtg gtaacatatt atataaagct ttggtattct tctcaaaatc aaaaaatgca
     4861 ggagttatag ttggggctaa agcaccaata atattaactt ctagagcaga cagtgaagaa
     4921 actaaactaa actcaatagc tttaggtgtt ttaatggcag caaaggcata attttaaggg
     4981 ggaaataggc aaatgagcaa aatatttaaa atcttaacaa taaatcctgg ttcgacatca
     5041 actaaaatag ctgtatttga taatgaggat ttagtatttg aaaaaacttt aagacattct
     5101 tcagaagaaa taggaaaata tgagaaggtg tctgaccaat ttgaatttcg taaacaagta
     5161 atagaagaag ctctaaaaga aggtggagta aaaacatctg aattagatgc tgtagtaggt
     5221 agaggaggac ttcttaaacc tataaaaggt ggtacttatt cagtaagtgc tgctatgatt
     5281 gaagatttaa aagtgggagt tttaggagaa cacgcttcaa acctaggtgg aataatagca
     5341 aaacaaatag gtgaagaagt aaatgttcct tcatacatag tagaccctgt tgttgtagat
     5401 gaattagaag atgttgctag aatttctggt atgcctgaaa taagtagagc aagtgtagta
     5461 catgctttaa atcaaaaggc aatagcaaga agatatgcta gagaaataaa caagaaatat
     5521 gaagatataa atcttatagt tgcacacatg ggtggaggag tttctgttgg agctcataaa
     5581 aatggtaaaa tagtagatgt tgcaaacgca ttagatggag aaggaccttt ctctccagaa
     5641 agaagtggtg gattaccagt aggtgcatta gtaaaaatgt gctttagtgg aaaatatact
     5701 caagatgaaa ttaaaaagaa aataaaaggt aatggcggat tagttgcata cttaaacact
     5761 aatgatgcta gagaagttga agaaagaatt gaagctggtg atgaaaaagc taaattagta
     5821 tatgaagcta tggcatatca aatctctaaa gaaataggag ctagtgctgc agttcttaag
     5881 ggagatgtaa aagcaatatt attaactggt ggaatcgcat attcaaaaat gtttacagaa
     5941 atgattgcag atagagttaa atttatagca gatgtaaaag tttatccagg tgaagatgaa
     6001 atgattgcat tagctcaagg tggacttaga gttttaactg gtgaagaaga ggctcaagtt
     6061 tatgataact aatgataaaa gaataagaat cataactggt cactatggaa gtggtaaaag
     6121 tgaatttgcg atgaactatg ttgttaagtt aagagatatg gtttctggca aagttgctat
     6181 agccgattta gatgtggtaa atgtatactt tagaactaga gaaaagaaag agttaatgaa
     6241 atccttaggt atacaaccaa tagatagctc aattaatgct ccaacattag atttaccagc
     6301 agtatcagca gaggtaatgt ctcctatggt agaccattca tacaattctg ttatagattt
     6361 aggtggagat aatgtaggtg ctagggttat aggaagattt agtcatttgt taaaagaagg
     6421 cgattatgat atgctttttg taataaatgc aaatagggag aaaactcaaa cttctgaaga
     6481 agttatccaa tatataaaag aaatagaaaa atcttctaaa ttaaaggtaa caggtctaat
     6541 taataatact catcttatta ggtttactac tattgatgat gttttaagag gtcagaaagt
     6601 tgcaaaagaa gtttctgaaa aatgtaatat accgataaga tatgttgcat gtttagaaaa
     6661 tcttgttgaa cagttaccaa aagatttaga aggagaaatt tttcctataa aattatatat
     6721 gagagaagac tggatgtagt ttgagctcaa atatatagaa agtttaagga ggcttaggta
     6781 aatggctaaa ggaaaagtat cttttaatca agaacgttgt aaaggttgtg gattgtgtgt
     6841 tgaagcatgt ccagtaaaaa tcatacaatt agactcaaat gtaataaaca aaaaagggta
     6901 taacccagca actgtttttg aaatggaaaa atgcatagga tgtgcaagtt gtgcaactat
     6961 gtgtccagat gtagttataa cagtagaaag agattaattt aattaatatt taagggggaa
     7021 ttttaatggc taagatactt atgaaaggta acgaagcatt tggaaaagca gctatagaag
     7081 ctggttgcaa atatttcttc ggttacccaa taactccaca aagtgaatta ccagaatatt
     7141 tatcaagaga gttacctaaa ataggtggag cgttcgttca agctgaatca gaagtttctg
     7201 cgataaacat ggtttatggt ggagcaggtg caggagcaag agttatgact tcttcatctt
     7261 caccaggagt tgctttaaag caagaaggta taacatatgc agtaggagca gaagttcctt
     7321 gtgttgtact taatgtaatg agaggtggtc caggacttgg aagtatacaa ccttcacaag
     7381 ctgactactt tatgtctaca agaggtggag gaaatggaga ctacagaact ccagtattcg
     7441 caccagctac agttcaagaa gctgttgata tgataatgga agcttttgac gttgcagatt
     7501 attacagatc accagttatg gtagttgcag atggtatgat aggtcaaatg atggagccag
     7561 ttgaatttag agctcctgag aagaaaagag aattgcctcc taaagattgg gcaactgttg
     7621 gaactaaagg aaaaagaaaa cctaatgtaa taaactctct atacttagag ccagaagtac
     7681 tagaagacca ttgttggcat ttacaagaaa aatttgatgc aatggaaaag aatgaagtac
     7741 aatacgaaat gtacaaaaca gaagatgctg aatttgtatt tgcagcttat ggaactactt
     7801 caagagtagt aaaaagcgca attgatatat taagagaaga aggaataaaa gcaggtctta
     7861 taagacctaa agtattatgg ccattcccat tcgaagcatt caaccaaatt cctaatgcta
     7921 gaaacatatt gactgttgaa atgagtatgg gacaaatggt ggaagatgtt aaaatggcag
     7981 tagaaggtaa attaccagtt tacttccatg gaagaccagg aggaatgact ccaacaccag
     8041 cagaaatagt tgaaaaagct aaaaaaatta ttgccggaga attggttgca ggaggtgcta
     8101 gataatggct gttgtattta agaaaactga aggattacaa gatactcaaa ctcactactg
     8161 tccaggatgt acacatggta taatccatag attagttggt gaagtattag aagaactagg
     8221 agtattaggt gatgctgtag gtgttgttcc agttggatgt tcagttttag gatataaata
     8281 ttttaactgt gacactcaag aagctgctca tggtagagcg ccagctgctg ctacaggaat
     8341 aaaaagagtt catcctgaaa atacagtatt cacttatcaa ggtgatggag acttagcttc
     8401 aattggtact gctgaaatag ttcatgcagc tgctagagga gaaaaaataa ctactatatt
     8461 tgtaaacaat acaacttatg gtatgactgg tggacaaatg gctccaacta cattagttgg
     8521 acaaagagct actactgctc aatcaggaag aaatgctgaa actcaaggtt atccaataag
     8581 agtaagtgaa atgttagcta cattaacagg agctgtattt gtagaaagag tagcagttga
     8641 tactccagct catgttagac aagctaaaaa agctataaag aaagcattcc aagttcaaca
     8701 agcaggatta ggatttggaa tagtagaagt attatctact tgtcctacaa actggggact
     8761 agctccaaat gatgctttac aatggttaag agacaacatg ataccatact atccattagg
     8821 aaatttcaaa aatgttgaag ttgaggaggt gaagtaaatg tctacagcta gagtaatatg
     8881 tgcaggcttc ggaggccaag gtgttatgtc tatgggacaa ttacttactt atgcaggaat
     8941 gctagaagga aaagaagttt cttggttacc atcttatgga ccagaaatgc gtggaggtac
     9001 agcaaactgt gcagtaactg tatctaatga gccagttggt tctccactta taacagatga
     9061 tgcaactgca gctatattat taaatatacc agcatttgaa aaattcaaag atgatgttat
     9121 tcctggtgga aaaataatag taaatagttc tttaataaaa gaaaaagttg atagaacaga
     9181 tgtagatgtt tattatatac cagcaaatga attagcagct gaattaggaa atgataaagt
     9241 tgctaacatg ataatgttag gcgcttactt aaaagtatct gatactgtag atatagaatc
     9301 tgtactagaa gcattcaaaa aagttttcgg acctagaaaa gaaaaattcg ttccattaaa
     9361 cagagaagct ttacaaaaag gtatggatgc tacatgttct aaagcaacta actaataaag
     9421 aaaaagatgt caaaaaaaag acaatagaat tatttctatt gtcttttttg ctgataagta
     9481 ttaaaatatt tttatgactg aaattaagcc tataatgata ttttatgaac tataaaaata
     9541 taatacaaat tacaagcttt tcaattatga aaggagaatc tttagtgaga aagtattttg
     9601 gaacagatgg agttagagga gtagcaaata cagaactaac atgtgattta gcatataaac
     9661 ttggtagagc tggtggattt gtcttagctc aaggagacca cagagtaaaa gtagtagtag
     9721 gtaaggatac tagaatatca ggtgatatgt tggaagcatc tttaatagca ggacttatgt
     9781 ctgttggatg tgatgttatt actgttggaa taataccaac acctgcagtg gcatatttaa
     9841 ctagaaaata tggtgctgat tgtggtgtgg ttatatctgc atctcacaat cctgttgaat
     9901 ataatggaat caaattcttt aataagaatg gatataaatt agatgatgaa attgaattga
     9961 aaatagaaga atatatagac gatatagaca aaattgattg tcttccaatt ggtgaaaatg
    10021 taggaagaaa attacatgaa cattgtgcac aaagagacta tgtagactac ctaaaatcaa
    10081 taataagcac tgactttaag ggattaaaag tagttttgga ctgtgctaat ggtgcgtcat
    10141 ataaagtggc accaatagtg tttgatgaac taggagcaag tgtaatttca ataaatagtt
    10201 caccagatgg aaataatata aactataaat gtggctctac acatccagaa caacttcaaa
    10261 gggctgtttt ggaacataat gctgacttag gtcttgcata tgatggagat gctgatagat
    10321 taattgcagt aaatgaaaag ggtcaaattg ttgatggaga ccatataatg atattgagtg
    10381 ccttaaattt aaagaaaaat aataaattgg cacaagatac tttggtagtt acagttatga
    10441 gtaatatagg gttgacaata gctgctaagg aaaatggaat aaatttatct actacagcag
    10501 ttggagacag atatgtttta gaagatatgg ttaaaaatgg atataatctt ggtggagagc
    10561 aatctggaca tatgatattt ttagattaca acactactgg agatggagtg cttagttctc
    10621 taatacttgc aaatataatc ttgcaagaaa agaaaccttt atcagaaatt gcatcaataa
    10681 tgagccaata cccacaagta ttagtaaatg caacaataaa aaatgaaaat aagaacaaat
    10741 atatggaata tccagaaata aaaactgaga tagaaagaat agaatctatt ttagacggaa
    10801 atggtagagt tttgataaga ccatcaggaa ctgagccatt agttagagtt atgttagagg
    10861 gtaaagagga aggtcaaata aaagaattag caacaaactt agctaatctt atacaagaaa
    10921 aattatcgta atttaaaggg tattctcaga tataaatact gaggacacct ttctaagcgc
    10981 cagaacttag ttatagacat aattattgag taatatagga actaagttga cgaggtcaga
    11041 gttaatcgaa ttgtcggcgg atgctctgcg gtgtgtttac catcgaaaga cttctttaaa
    11101 taataggagc aatcctatgg acaaagggaa gccaaagtaa acttatatga cctaactctt
    11161 aaaatatata aataatattt ttaggaggac acaaataatg tgtggaatag ttggatattt
    11221 aggaagtaga aaggcagcag aagttatagt agaagggctt tctaagctag agtacagagg
    11281 ttatgactca gcaggagtag cagttaatag ttctaatgaa aaagaactta atattagaaa
    11341 gtttaaaggt agactttctg tacttgcaga agacttagaa aagaatccta ttgatggaaa
    11401 tttaggtata gggcatacga gatgggcaac tcatggagaa ccatctgatg taaactcaca
    11461 tcctcatttt aatcaagcca aaacaatagc agttgttcat aatgggataa tagaaaacta
    11521 tatggaaata aaagaagaat taatttctga aggtgttaag tttgaatctc aaacagatac
    11581 agaggtaata gcacatttag tagataaata ctatgagggt aatttattag atgctgtata
    11641 caaaactata tcaaaattaa gaggagctta tgcattaggt gttatatgta aagaacatgg
    11701 aaatgaatta gttgcagtaa gaaaagatag tcctcttgta gttggtgttg gtgaaggtga
    11761 aaactttata gcatcagata tacctgcatt attaaaatat actagagatg tttatttctt
    11821 agaaaatgga gaagtagttc atctaaaaga cgaaaatgta acagtttatg actctaatag
    11881 aaatcttgtt gaaaaagaag tatttcatgt aacttgggat gtagaagctg cgtctaaagg
    11941 tggatatgac tactttatgt caaaagaaat tcatgagcaa ccaacaggag taagagaaac
    12001 tttagaaaga agacttgatg ataatggaaa tataattcta gacagtataa atatttctaa
    12061 agaagactta gaaaaaataa ataaagttta tatagtggct tgtggaacag catataatgc
    12121 tggattactt ggtaagtatg ccatagaaaa atttgtaaat ataccagtaa taactgatat
    12181 agcatcagaa tttagatata gcgacccatt tgtagatgaa aattcattag taatattagt
    12241 tagtcaatct ggtgagacag cagatactct agcagtatta agagattcaa aggctaaagg
    12301 agcaagaata ctttcaataa ctaacgttgt aggttcatct atagcaagag aatcagatga
    12361 tgtattctat acttgggcag gacctgaagt agcagttgca tcaactaagg catatactac
    12421 tcaaataact tctttataca tgatagcttt agactttgct atcaaaaaag gaacaataac
    12481 tagagaattt tatgatagta tgatttctaa gatgaaagaa ataccatcaa aaatacaaga
    12541 aatactagac aatgaagaat atataaaaga agttgctaaa acagttgtta gttctgaaca
    12601 tgcattctat ttaggaagag gtatagacta tagcttagca atggaaggtt cattgaaatt
    12661 aaaagagatt tcatatatac atgcagaagc ttttgcagca ggagagctaa agcatggaac
    12721 aatagcttta atagaaaaag gaactcctgt aattgccata gctactcaag aaaagttatt
    12781 tgaaaaaatg gtttctaata tggaagaagt aagagcaaga ggagcttatg tagtagcaat
    12841 agctcaaagc cataataagg atgttgagaa agctgctgat aaaataatct atataccaaa
    12901 ttcagatgat attttatcac caatattagc agttgtacca atgcaattac ttgcttatca
    12961 tgtctctgta ctaagaggat gcgatgtaga taagccaaga aatctagcta aatcagtaac
    13021 agttgaataa aaacagatta aaaattaaat agataatatt tattgaaaag aactcatcct
    13081 gttatttgta ttttatagga tgagtttttt agataaatat taaatttgtt ttgtttttgc
    13141 tataataaat tttataaaaa gattgatatt aaatcatctg taaaatgata aatatataga
    13201 ccataccagg tatagggaac gataaatata gttcatataa aatatagtga gtacttaata
    13261 aacatatagt caatatcaga taaaaaaaat aatagcttat gagaaaaatt aaaatacaag
    13321 gtattagtaa ccttgtgata agataaagtg agtagtttaa aataagaata taaggaacta
    13381 tttataaaag aatataatga agctaataga gtataagaaa attactttat tttagtaaaa
    13441 taatttcaaa taaaaatttt tttaaattgg gagtataaat tatgacaaat gattttaaaa
    13501 aagaaaagaa agaagattat tttgttaatc ttaaggcaat atctactgaa gttttacaag
    13561 aaaaagtgca agataacgct tgggttatag ttgatactcg cttaaatgat gcttataatg
    13621 gctggaagtt agatggagta aaaagaggtg gacatataaa aggagcagta gatttttctg
    13681 ctaattggtt aagtgtatac tcagatagaa aagatgaagt gttagaacaa gcattgaaaa
    13741 ctaaaagaat tgatttagat aaaaatatag tattgtatga tgcaaatgga aaagatgctt
    13801 tggttgtagc aaattattta tctaaaaaag gatataaata tctatataaa tatgatatta
    13861 aacaatgggc agacgacgaa aatcttccaa tggaaagata taaaaattat caaatgatag
    13921 ttcctgcttt tataataaaa gatatattag atggaaaaat tcctgagaca tttgaagatt
    13981 caaagaatat aaaaatgatt gaagcgagtt ggggaaaaga atcgtataca aaagggcata
    14041 tacctacaag tgttcatgta aatactgata ttatagaacc tcctccaaca tggatgcttg
    14101 ataatgatga taacttaact aagtttgctt tagactatgg attaacaaag gatgatactg
    14161 taatagtttc aagtagtaca cctatggcat cttatagact agctgttata ttgagatata
    14221 taggagtaaa agatgtaaga gttttgaatg gtggaacaaa ctcatggtta tcagcaggat
    14281 atgaattaga atttattagt aatccaaaac attcatgtac taattttgga gcagatatac
    14341 cagttaactc acaattaatt gttactacat ctgaattaag acaaaaacta aaagaaaaaa
    14401 ataagtttat actagtagat aaccgtactt gggatgaaca tataggaaaa gtatctggat
    14461 atacatatta tgataaaaaa gggcgtatac caggagcttt atatggacat tcaggtagtg
    14521 atagtgtttc actagaagaa tatcgtaata ttgataatac aatgagaaat aaatatgaga
    14581 ttttagaaat gtgggacaag gaaaatatag atgtgaataa acagcttata tttatgtgtg
    14641 gaagtggatg gcgtgctgct gaagtattaa catatgcaaa tgtcatagga gtggaaaata
    14701 cctcccttta tagtgatgga tggatgggct ggagtcttga taattcaaat ttaattgaag
    14761 tgggagaaca caaataaagt ttttgaaagt gcaatagagt tgtttaaaac aaaggtgttt
    14821 ttgatttatt aggaagagtg tgtaaattgt gtattgggaa gtgtacttag gtatgttcat
    14881 ttggagctat ggaaattgac aaaaaagtat tatctgttta ttttgttggt aaaatatgaa
    14941 tagattatag atttaagtat agactaagta atttatatta cagaagagaa tatataagaa
    15001 ttaatgcaag atgtatttga tacatataag aaattggcaa gtccaggaga aggatagaga
    15061 aaattgagat tgaagagttt gaaagagatt attagatgaa aaatacaaaa atgtataaaa
    15121 atacatattg agaaagtata tctctcttaa atttgttaat aattctatta tacagaaaaa
    15181 catatttaag ggggattttt tactatgaaa aaagtaaaat tagctataag cttttttata
    15241 ttaatgatta taggaatgac aatatcttat gcagatacaa gtataaatac tagatacaat
    15301 agattaagta aagctcttga aatatcagaa gcaaatttta aattttataa tgttaaaatt
    15361 aattctgtta taaatcataa tttatcaaat aaagaatttc ataatatttt tatagaaata
    15421 attaacaatc taaagttgga taaaaaagga ataaattgga atcaaaaagg gtctggcgat
    15481 aaaatacaat tatgtgctac tataaaaggt agcgataaag aaatttctat aaaaggaata
    15541 aataaaaata acaaagaaag ttacatagta gttgacatat tggataacaa agtatataaa
    15601 cataaagagg ttatttatag taacgtagaa aatgtgttaa ataaatattc atctcaagta
    15661 gatgtgtctg cttgtattgt tggagaatac acaaaaaggt tacaaaacaa caaatatgat
    15721 gatattttac aaaaaatatt atataatatg agtgctaagc aaatagatga agttaaagac
    15781 gtaaactttt tatctataac agcatatagt aaagtattaa atgattatga attagaatat
    15841 ttaggggaaa aaattaattt aaatatagga attaaatata atgaggatga cggaaaaaca
    15901 ctcatatata ttgccacacc aattataaaa ttagattatt aattatgagg agatcaaaaa
    15961 atatggctaa gataatagta aaaaagagta atccacttaa aggtagtgtt aaaatagatg
    16021 gtgcaaaaaa tgcagtttta ccaataatag cagcgacttt attagcaaac ggaaaatcaa
    16081 cattaaatgg agtaccaaat ttaagagatg ttcatgttat atcagattta ttaagacatg
    16141 taggagcaga agttgaatat aaagaaaata cacttactgt tgatgcaagc aatataaaaa
    16201 cttgtgaagc tccatatgag cttgtaagaa agatgagagc ttcttttttg gttatgggac
    16261 cattgcttgc tagatttaat agtacgaaaa tttctatgcc aggaggatgt gctataggaa
    16321 caagacctat agatttacat ttaaaaggat ttaaagcctt aggtgcaaag atagaaatga
    16381 accatggttt tgttgaagca gcaacagaaa agttagtagg aaataaatta tatttagatt
    16441 tcccatctgt tggagcaact gaaaacataa tgatggcagc ttctttagca gaagggacta
    16501 caataataga gaatgcagca gaagagccag aaatagtaga tttagcaaac ttcttgaacg
    16561 aaatgggagc agatgttaaa ggtgcaggta ctaatactat aaaaataaaa ggtgttaaag
    16621 agttaaaagg agcagaacat aatgtaattc cagacagaat agaagcagca acttatatgg
    16681 ttgcagcagc tatgacaaaa ggtgatataa ctgttgaaaa tgttttaatg gagcatttaa
    16741 aactagttgt agctaaatta agagaagctg gttgtgaaat aacagaaatg gacaattctg
    16801 taagagttgt aggtccaaaa gtattaaaac caatagatat aaaaacttta ccacatccag
    16861 gatttcctac agatgttcaa gcacaattta tggctatgct tactgtagcc aatggaactg
    16921 gtgtagttat agaaactgtt tttgaaaata gatttatgca tgttgctgaa tttaatagaa
    16981 tgggtgctaa tataaaaata gatggaagaa gtgcggttgt taatggtgta gatgagctac
    17041 acggtgcagc agtaaacgct actgatttaa gagcaggggc agcccttatt ttatgcggtc
    17101 ttatagcaga aggagaaact caaataggag aaatatacca tatccaaaga ggttatgttg
    17161 atatagataa gaagataaca gcactaggtg gtcaaatcga aatagtagaa gattaataat
    17221 tggtttatag aagaaagtta taaattaata gggttgttca tatacttaaa tacaaggttt
    17281 taaaagctaa ggaggagagt atatgaagaa cccattggtt gttttgttag gatttgtgac
    17341 ttgctctgtg ttagttccat cacttataac tttagtttct tataaaaatg tagaattaac
    17401 tgaaaaacca gagagcccag tatctataaa caaaactatt aaaaaaagtg atattgaaga
    17461 caaaggtaat aaagaagaaa aaaatacagt gaactatgaa actgtaaata aaaaagcacc
    17521 aattatcaat gtatataatc atataacagg gaaaaccgaa aagatggaca tggagaacta
    17581 tttatgtgga gtactagctg gtgagatgtc ttcagagttt gatatagaag ctttaaaagc
    17641 tcaatctgta gcagctagaa catatgtagt atataaacag gaacatggta aatctagtaa
    17701 acataaaaat gcagtagtat gtactgatta taaacattgt caagaatata agagttatga
    17761 tactcttaaa aaattaaatg gtgaagaatg gattaagaat aaatattcca aaatccaaga
    17821 agcagttaga ggaactaaag gtcaaataat aacttataat gataaggcga tacttcctct
    17881 ttatttttct acatcttcag gaaaaacaga aaatagtgaa gaagtatttt ctgcaaaata
    17941 tccttattta aagtctgtgg aaagtcctta tgataagtat tcccctaaat ttgcgtcaac
    18001 acttaaaata agtaacacag attttgttaa aagtcttaga agggcatata gcactattgt
    18061 gatagatgtg aataatttaa gtaaacaagt ttcaataact aaaagaagtg atgccggaac
    18121 tgtagaaaaa ataaaattag gaaataaaga attgactgga aaagacatta gaactgtttt
    18181 taaattgaac tctgcaaact ttgacataaa atttggagaa ggatacatag atttcgtggt
    18241 aaaaggatat ggtcatggtg ttggtatgag ccagtgggga gcagaaggaa tggcagaaga
    18301 gggctataaa tattatgata tattatcaca ttactacaca gatacaaaaa taaaagatat
    18361 atactaataa ttgtataaaa tgccaaaaac acgtcaataa tccaaatgta gaaatatatt
    18421 tggaggtgca aaatgaagaa aaagctgtta gaaaaagatg gtttttattt atctttgttt
    18481 gtatgtgttt gtttattagc agtaggtgga gtttggttta caaataataa tgtagataaa
    18541 ttggcttcta ataaaggaat tatggaaaat gctaataaag atagtgaaga ggaaatacat
    18601 ttaattgaaa aagacaagaa agatgctatc cctactgcaa cggattcaaa acaaaactta
    18661 gaaaaagcta agtcaaaaga ggaaaataaa tcgagtacaa caaaattaaa ttacattgga
    18721 gataaagtaa taagaggata ttcagaaaaa gagcctagtt attctaaaac acttgatgtt
    18781 tgggaaactc ataaaggtgt agatattagt tgtactaaag gcaaagaagt aaaatctcta
    18841 ttaaacggaa tagtagtaga tgtatttgat gatgaagaat atggacaatc agtcaaaata
    18901 aaaagtgaca ataacattgt agtagtatat tcaaatctag ataaaaatgt tagtgttaag
    18961 aaagaacaga aggtaacaga aggacaatct ctaggtactg taggtagtac ttctcaaata
    19021 gaaagtgaag aaggtataca tgtgcattta gaggcgtata gtggagaaaa atctatagac
    19081 ccaatgagtc taattaagta atagtataac aagtttaatc atatttggtt aagcttgtta
    19141 tattttttgg tgtttttaca tatatatcat taaagctatt atgtgagggg ggtaatcttt
    19201 gagatctcat atagaggaaa gggccatagt ggtagcaaaa tatatacttg aaaaaaacac
    19261 tacagtaaga caaaccgcca agacatttgg agtaagtaaa agtacaattc ataaggatgt
    19321 tacagaaaga ttgaaggaaa taaatccatc ccttgccaaa gaagttaaaa atgtgctgga
    19381 caaaaataaa tcagagagac atattagagg gggattagca acgaaattaa aatatgagaa
    19441 ggaacataaa aaaatgtagg ttaaaaacct acttttttta ttgaattaaa ttataaaaag
    19501 aaatatatta agtaattata aatagcaaaa taataatact ctcaaaagat ttattttctc
    19561 ttgattaaag cgagattttt gtatatgctt tattatagga gtattaaaat aggcttataa
    19621 tataatctaa tattataaat aaaggagttg aaaaaatggc tggagctgat ataggcatag
    19681 atttaggtac tgcaaatgtg cttgtttatg ttagtggtaa gggaatcgtt ttagaagaac
    19741 catctgttgt ggcgatagac aaaagaacag attctgtttt agctgtggga gaagaagcta
    19801 aaaagatgat agggagaaca ccaggtaata tagtcgctat aagaccttta agagatggtg
    19861 taatttcaga ttatgatgta actgagaaga tgttaaaatc ttttatagat aagatagttg
    19921 ataaaaaggg atttggaaga ttttttatgc caagaattat ggtatgtgta ccaacaggtg
    19981 tcacagaagt ggaaaaaaga gcagtagaag atgctacgag acaagctgga gctagagaag
    20041 tatatatcat agaagaacca atagcagctg ccataggagc tggtgtagac atatcacagc
    20101 ctaatggtaa tatgattata gatattggtg gaggtactgt agatatagct gtaatatctc
    20161 taggaggagc tgttgtaagt gaatctataa aggttggtgg agatagattt gatgatgcta
    20221 tagttaaata tatgaaaaaa caacacaatc ttcttatagg agaaagaaca gcagagaaaa
    20281 tcaagtttga aataggttct gcatttaaga gagaagaaga aaaatatatg aagataacag
    20341 gaagaaattt aattacagga cttcctagtt ctataactat aaattcaaca gaaatgttgg
    20401 aagcacttag agaatgtgtt gagcaaatag tagttgctac tcatgctgtt ttggaaaaaa
    20461 cgcctcctga gttagcagca gatataggag atgtcggtat aataatgact ggaggaggtt
    20521 cattattata tggattagat aaaataatag aacagaggac aggaataact gttacaatag
    20581 cagatgaacc attatcttgt gttgcaaaag gtacaggaat agctttaggt tcaatagact
    20641 tacttgaaac tggtgggtct ttcaaaagaa aataattagg agagtttaga atgttaaata
    20701 tagatgaaat aaaaaaatta ataccacata gatatccatt tttattagta gacaagatta
    20761 cagagctaga agttgggaaa agagctgttg gtataaagaa tgtaacagtt aatgagccat
    20821 ttttccaagg tcactttcca gaatatcctt tgatgccagg agtactaata gtagaagctc
    20881 tagcacaagt atgtggagtg gcaatgatgt ctgtagagga aaacaaagga aaactaggtg
    20941 tatttgcagg tatagataaa gttagaatca agagagaagt aagaccagga gatacattaa
    21001 ctatggaagt tgaaatgaca actcttagaa aaaatatagc taaggcagat gctaaggcat
    21061 atgtaggtga agaacttgtc tgtaaaggtg aattaatgtt tgctttagta gaaaaataaa
    21121 aacttgaaat ataaaagtaa aaaggtagat aatttggagt atttaatcag atactctaaa
    21181 atatctacct ttttatataa agaattttat catttagttt atatttagat taggtggata
    21241 ctaataaagc caaggctatt gtttcagcta aatctaatat aaagctaagg cgtatattat
    21301 taaatgaaag tttattattt tcatcaattt tatctacaat tcctactata gaataatttc
    21361 ctatttgagg tagtttttta ccaacacctt ttccgggcag gataggtcct tctctaatct
    21421 gtatattacc tatgttactc tgcgacccca agcaagcatc tatagccaag aagttacctt
    21481 gtatatgtgt attttttata gtatctaaag actcatatat atttaaggcg tgaatagggt
    21541 tatctagtgt accgtaaacg gggtatttaa agttactgtt cttaagtatt gttccaacta
    21601 aagggcctaa agtatcacct atagccctgt ctgttcctat gcaaacaaca atcgtatttt
    21661 cattaattat agtttttaga actgaactta gcatctgtat aacatcatca tcgctgtagt
    21721 ttactttagc taaatacaat aggaacaccc ccttcaaaaa aatatatgaa taaaaagcat
    21781 taaaaagacc taactttaaa tttcagatag atagaaaatt ttatttgtct tacaaaaaaa
    21841 ggaatagaaa aaatatgact aaaaatattg acaaaatttt aaaaaaatag taagctagta
    21901 aagtaaaaca aaacttaaat cttgattacc ttatcaagag aggctgaggg ataggccctg
    21961 tgaagcccag caaccaccca aatgggaaaa ggtgctaatt cctacaagac aaaagtcttg
    22021 aaagatgagg tcagttaatt agtatgtaat tacgattatt aacctcttct tataaaggag
    22081 aggttttttt attttgagta aatttctaaa attaaaaata aggtaaaacc tataataaaa
    22141 attaagaata aataaggggg aataaaaatg gcaagacatt tatttacgtc agaatcagtt
    22201 acagaaggac atcctgataa gatatgtgac caaatatcag attcaatatt agatgcatta
    22261 ttagaaaaag acccacaatc tagagtagct tgtgaaacta cagttactac tggtttagtt
    22321 ttagtagcag gagaaataag tacatctgct tatgtagaca ttcctaaatt agtaagagaa
    22381 acagtaagag aaattggata tacaagagca aaatatggat ttgattgtga tacttgcgca
    22441 gttataactt ctattgatga acaatctgga gatatagcta tgggagttga tgaaggccta
    22501 gaaagtaaga ctggagaaga gatagaagaa gaaatagaaa aagttggagc tggagaccaa
    22561 ggtataatgt ttggatttgc atgtaatgag actccagaat taatgccact tccgatatct
    22621 ttggcacata aattatcaag aagacttaca gaagttagaa aaacaggttt agttgattat
    22681 ttaagaccag atggaaaaac tcaagttact gttgaatatg aaggaagtaa agctgtaaga
    22741 gtacatacag ttcttatatc agctcaacat tgtgaaacag tatcaaatga taaaataaga
    22801 gaagatttaa ttaatcatgt tattaaggaa gttataccag cagaattact tgatgaagag
    22861 actaaaattt atataaatcc aacaggaaga ttcgttatag gaggaccaca aggagataca
    22921 ggtcttacag gaagaaaaat aataatagat acttatggtg gatattctag acatggtgga
    22981 ggagctttct caggaaaaga ccctacaaaa gttgatagat ctgctgctta cgcagctaga
    23041 tatgttgcaa aaaatattgt tgcggctggt cttgcagaca aatgtgagat agaacttgca
    23101 tatgctatag gtatagctag accattatct atatttatag atacttttgg gacaggcaag
    23161 gtttcagaag aaaaacttgt tgaattagta aataaacact ttgatttaag accaggagcg
    23221 ataataagag acttagattt aagaaagcct ctttataaaa aggttgctgc ttatggtcac
    23281 tttggtagaa ctgatataga tttaccttgg gaaagaactg acaaggttga gcagttaaga
    23341 aaagatgctt taggtgaata atttttaact aaaaagctgt tagaatgtaa ttttacgatt
    23401 actttctaac agctttttta ttatgagtta aatattttta ataaatgtta atttatcatc
    23461 atataatgaa taaacagtat ttaatctggt caatacattt tatataatac tctactaaat
    23521 ttatacatat tatgggatat atgttaaagg atggttaaga atgtgttaac taatgttaaa
    23581 taattaaaaa tatattgaaa tatcacaata atgagtctaa tataatctta ataaacttac
    23641 actttaaaaa taattttaat tgggggggag tagtgtatgt caggcaaagt aaatattaaa
    23701 acggttataa gttttgctgg agcttatgtt gctactgtaa taggttctgg atttgcaact
    23761 ggtcaagaaa tactgcaatt ttttacgttt tatggatatg cgggtattat aggtggaata
    23821 atctctatgg tactattttc atggtttgga gcagaagtta tagataaggg aagagaattg
    23881 aaacttaagg agccaataaa aatttatcaa gtatattgtg gaaaatatct tggaacattt
    23941 tttgaatggt ttggtccatt gtttttattt ggaacattag taataatgat tgcaggagca
    24001 ggagctacat tatcagagta ctatggatta aatccatatg taggtaggat tggtatggca
    24061 atcgtttccc taataactgt ttcattaggt ttgacaaggc tttctaaaat actaggtaat
    24121 ataggaccta taataataat atttacactt ttagtaggag caattagttt atttagcaat
    24181 attgatgctt tatcaaatgc tggaaatatg gttgatagtt taaatattaa aactgctaca
    24241 tcaaatggat atttctcggg agtactttat acttgttaca atgtaataat agtaataaca
    24301 ttcttgacag gaatgggagc ttctgcagta aataagaaag atgctgtatg gggtggtata
    24361 gtaggtggag tagcacttat ggcagcagct ataatgatga atttggcatt actttcagac
    24421 ataggaaata tatacacaaa agagatacca gcactttact tagctgataa gatatctcca
    24481 ataataggta ttttattctc agtagtactt ttactaggaa tatacactac agctgtacca
    24541 ttgttatggt cagtaacaaa ccgatttgta gaagatgacc accctaagtt taaaattata
    24601 acaatagtgg taagtatatt agcttgtata ggaggtttac tgccatttga taagttagta
    24661 ggtacactat atccatatac aggttacatg ggaattttaa ttttactatg tatgctttat
    24721 agaagaatta ctaaaactga ggggtacaag gagaataaat ctgaaataag ttagtactgt
    24781 aatatactta tgaaatttaa tttatactct aaatatagag taattaaaat aaaatagcta
    24841 tttaaatatg gtacctgtat ttcatggtac catattttat ggatgcagat tttttttgtt
    24901 tctgataaaa tgtataatag ttggaaatta cgttaagtat aaaaatataa aacttttcta
    24961 cgattatcat agttttaata tataaaatta tactaacatt taaatggagc gattattagt
    25021 atttttagga gataaaaatg gaaaaattag aaggaatgat aagtgaaata gtctttaaaa
    25081 acgaagataa tggttataca atagctcacc tggtaaatga aaatgatgaa attgtggttg
    25141 taggatgtat gcctactttg gcaattggag aaagcataga agttgaagga aagtgggtaa
    25201 atcataagat ttatgggact caatttgaag tgaatagttt tatgccagta acaccatcat
    25261 ccttagaagg aatttatgtt tacttatctt ctggaatgat acatggtatt ggtgaaaaaa
    25321 tggcaaaaag aataattgat aagtttggtg tagatacgtt agaggtgata caaaattcac
    25381 cagaaaaact acaagaagta gaaggcatag ggagtaaaaa agtaaaacaa atagtaaaaa
    25441 gttatgaaga agacagagaa ttgagaaata taataataca gctatctcct tttggaataa
    25501 caccaaatta ctgcctaaaa atatataaaa aatataaaag cagtgcaata gaagttataa
    25561 ataaaaaccc ataccaactt gctgaagata taagaggaat tggatttaaa gtagctgata
    25621 gtatagcaag taaaattggt atagataaaa actctaaaga tagaatttgt cagggaatct
    25681 tatacacttt aaataaatct ttaagtaatg ggcatacata tttaccagag catgttctaa
    25741 tacaagattc ggaaaaatta ttggagctaa atggagaaat aataaaagag tgtgtaatga
    25801 tgctagttta taatcaaaaa atacatatag agaaagtaaa caatgaaaat cttatatacc
    25861 ttatgccata ctatttagct gaaaatggag tatgtagtca aatagtaaaa ttatcacagt
    25921 atgaatttga agacttaaaa atagatatag ataacgagat taatgtttta gaagaagata
    25981 agaaaattaa gttagcagaa aaacaaattt tagcagtcaa agaatctgtt aatagtggag
    26041 tattaattat aactggtgga ccaggaactg gtaaaacaac taccattaat gctatcatag
    26101 atatatttga aaataatggt aaaagtgtga ctttggcagc tccaacggga agagcagcaa
    26161 agagaatgag tgaaacttct aataaagaag caaaaactat acataggttg ctagaaatgg
    26221 gattttcaac agatgatgat ttaacttttt ttaaggatga agaagaccca ataaattcag
    26281 atgtaataat tgttgatgag gtatcaatgg tagacattat cttaatgtac aatttactta
    26341 gagctataaa gttaggaaca agagtaattt tagttggaga tagtgaccaa ttaccttctg
    26401 taggtgctgg aaatgtactt aaggatatga ttaattctaa tattataaat gtagttaaat
    26461 taaatgaaat atttagacaa gcgcaagaaa gtatgataat tgtaaatgcc cataagataa
    26521 acaatggaga accactttat ctaaatacaa aaggtaaaga tttctttttt ataagaaaat
    26581 caactaatga agaaatttta aatgaaataa taggattggt taatgaaaga ttacctaaat
    26641 tttataaagt tgataaatta aaagatatac aagttttatc ttcaatgaga aaaggtgaat
    26701 tgggagttac taatctcaat atagagttac agaagtatct taacaaaaaa gaaaaattta
    26761 aagttgaaga aagtttttct aaaagattat ttagagttgg cgataaggta atgcaagtaa
    26821 aaaataatta tacaaaaaaa tgggaaacag aagaccaaaa agaaagtgga gaaggtatct
    26881 ataatggaga tataggatat gtttatcaca tagataaaga taagaaaact atttatatat
    26941 tatttgacca gactaaaatt gtatcatacc tatatgatga attagatgaa attgaccata
    27001 gtttttgtac aacaatacat aaaagccagg gaagtgaatt tccagttgta gtattgccaa
    27061 tagcgtgggc tcctcctatg ttacttagcc gtaatttatt atatacagca gtaacaagag
    27121 caaaaaaatt agttgtatta gttggagatg tgaaatatct tgaatatatg ataaaaaata
    27181 atagagttaa tcaaaggtat tcaaatttag gatataagct aaataaattt aaacaagaag
    27241 ggttgttgat agaataaata tgaaaatatg caatgataat tttattaaga attttaaaaa
    27301 tatgattaat aaatgtttgg attttatata tcctgagaat ataagttgca taatttgtga
    27361 taaatccata aagaaaacaa atacttattc aatatgtaaa agttgtttta aagaaatgaa
    27421 ttttatacaa gatggttgca tgaagtgtgg aaaaccaata atatgtcatt caattgaaaa
    27481 agaatttatt gaagagtgta gttattgttt taataaagac ttttattttg ataaatcaat
    27541 atcttgtatt gaatacaatg atgtgacaaa aaagatggtg ttagggctga agtataacca
    27601 aaaaaccttt atggctaagt atatagctca aataatgaaa gaaaaattat atttagaaaa
    27661 cataaaattt gattatatat tatttgttcc acttcataaa aaaaggctaa ataaaagagg
    27721 ttttaatcag gcacaaaaaa tagcatttaa tttaagtaaa atagtaaata ttccattatt
    27781 agattgcata agtagaaaaa aatatacaag aatgctatat aaattgaata agaaagaacg
    27841 aaaagaagaa ttaaaaaatg tatttgttgt taaagaaaat gttaaattaa taaataataa
    27901 aaatatactt ttaatagatg atatatttac tactggtcta acaacaaacg aaatttctaa
    27961 acttttaaag ttatcaggtg ctaataaggt ttttgtattg actctactta caaaagcaaa
    28021 tgataattat attatggaat aatcttatat attgacaatt ttagtttaaa atattaaaat
    28081 gaataagtga tatttaggtc tgtggttgaa agtccaagcc agtcgcaggc aaagggatcc
    28141 acgtaagtta acactaaaaa ttgggttaat gatcatggtg cggcttagaa gtaagaccta
    28201 ccgataataa aatcgagaga gagtagtagt gcggcgaacc caagcgaacc ctccagtagg
    28261 cgagtgtggg gtcaaaaacc aggtcagcta aatatcatat taaaagagag ctagcatacc
    28321 tttatgtata gctctttttt atatataata aatttaggtt gagtcataaa gaggtgatat
    28381 gtttgaataa aagacaagaa aatttattaa caacattgct attaaaagaa gagtttataa
    28441 atgttaataa gattgccaat gattttgagt gttcagaaag gacaataaga aatgattgca
    28501 aatatattga tgaatggtta tctacttttt gtaatgctta tatcaaaaga aaacctaata
    28561 ttgggattaa atttagtgga gatggaacag acaaaatact ggtaaatcag aagttgcgag
    28621 gtgaagttaa aagagtaaat agtgagcttc ataagcaagt tgagatatta aatttactac
    28681 tttgtaataa taaaaaagtt actttaaatg atttatctaa taagttgtac ataaataaaa
    28741 atattgtcag agaagaaata agtaaattat cagtagcatt aaataattat aatttaaata
    28801 tctcgactaa aaaaggcagt ggtatatata ttgaagggga tgagaaagac ataagaataa
    28861 tgttagtatc attcttattt aaatatatag ataaatacag attaaacata gatgaaatag
    28921 agtacttcca tatagtagat ataataattg taaaaaacat aatgcttact atagaggagg
    28981 atatggatat aagacttaca gatatatcat tcaagcaatt gatgctattt ttgcttataa
    29041 atataatacg aataaggctg ggaaattctt taaaagtatc aaatactaag aaagagctta
    29101 agctaaaaat gcttatattg gatatagaag atgaattgaa atctaattta tccatagtat
    29161 taaattatga agaaaaattg tttatagaat ctttaatatt gggtatgaac aaacaaataa
    29221 atagtaataa tattaagaaa tctttatatc taaatgaaga attagcaagt tatacaaaaa
    29281 aaattataaa tttagtatca gaagaatcag gaataaattt taataatgat atattacttt
    29341 atgaacaatt aatatgtcat ttgaatgtta caatgcatca aatgaaaagc aatgtttact
    29401 tagaaaatcc acttttagat aacataaaaa ctaaattttg ttttttattt acagtaatat
    29461 caagttcaat agaaattgaa ttaaaaggaa aacaaataac ggaagatgaa attggttatc
    29521 ttacacttca ctttcaaacc tctctagaaa gaaaatacag caaaagggaa tcaaataaaa
    29581 aggcaagtat tgtatgtcca tttagttttg gagtaagtat gctattaaaa gtaaagatag
    29641 aaaagagatt tgataacata aaaattattg aaacattaag agaggaagat ttaaaaagag
    29701 ataactttaa taagactata gattttataa ttgcatttca agagtatgaa aatatccaaa
    29761 aaccaatttt tataacaaca ccattattta ctgatgagga tgagaataaa cttaaagagt
    29821 tcacaaacaa aataaaagaa aaagacactt catataaact tatgaacaga ttaatgatgt
    29881 ctgattattt aataagagag ttagaacatg atgatattta tgaagctata acatatttaa
    29941 ctaatttatt aattgaaaaa cattatgcag aaaaagagta tttacaatct attataacaa
    30001 gagaaaagtc atatccaacc aatgttggaa aaggaatatt attccctcat ggagacatga
    30061 aatatataaa acaatctgtt ttatgttttg caaggttaaa aacaccaata aaaattagaa
    30121 atggaaagga tataaagatt atacttttgt tagcatataa aaaagatgat gatagaaaag
    30181 tatttagaga attatttaaa gaaatatcta atttaacaga ggatgaaaat atgctagata
    30241 ttctaagtaa atgtgacatt gaaaaggtaa aagatattct tatataaaat tcatagtgaa
    30301 ctatggataa gcacaaaatt ttccatgtga tggaaaaagt tgtgcatgtt tttttgtttt
    30361 tataagatat tatatgtttg taaggtataa ataatctaaa agtagagaag caacttagga
    30421 ggaaaaaatg gaagaaatag ttttaaagat tataattcat gctggaaatg caaaatctat
    30481 gctttatgag gcacttgact atgcaaagga aaacgatttt aaaaaagcag atgaattaat
    30541 tgaaaatgca aatgaagaaa ttttaaaagc acataaagta caaactgaac ttatacaaaa
    30601 ggaagctggg ggagataaat cagatatatc tattttattg attcactctc aagaccattt
    30661 aatgacttgt atgagtgaga gaaaccttat aaaagaaatg attatgttaa gaaaagaaat
    30721 tcaaaaacta aaataaaaaa ttaaggggga tttaaaaaat gaaaagaaaa gtatatttat
    30781 tttgtagctt tggtatgtca acaagtttac ttgcagataa aatgcagaag gtagcagatg
    30841 aacacaattt accaatagaa gtagaggcat ttccgatagc agaaattgac aaaatagttg
    30901 aagaaaaaaa tccagattgt atattattag gaccacaagt taaatacatg ctaaaggagt
    30961 taaaaccaaa gtttgaagct caaggaaaac ttatagatat aatcaatgaa gttgattatg
    31021 gaactatgaa tggggaaaaa gtattaaaac ttgctataaa gctaataaaa tctaaacaag
    31081 cgtagaatta tagtaaaaaa taataggaaa tgagggtgga tagatgaata gattggaaag
    31141 aatacttatg ccattggctg aaaaaatagg taaaaataaa ttattaattg caattagaga
    31201 tggtttttta gtatcatcac cattattaat aataggttca ttatttttat tagtagcaaa
    31261 ttttcctata aaaggatgga atgaatttgt aggtcaaatt tttggtccag attgggctgt
    31321 aaaattgcaa caaccaactg tagcaacatt tgaagtaatg actctacttg cagttttagg
    31381 gattggatat tcttatgcaa agcaaataga tgtagaccca atagcatcag cagcagttgc
    31441 aatagttgcc ttttttataa taacaccatt tgtaatacca tatacaccag aaggaacaga
    31501 atcagtttac atggtaacag gtataccact aggttggatg ggttctaagg gaatgtttgt
    31561 aggtatgata acagcaataa cctctgtaaa attatttgct gcagttgtaa aaaaaggatg
    31621 gacattgaaa atgccagatg gagttcctcc aactgtatca aaatcatttg cagcattaat
    31681 accaagtgca atagttatgg tagttttctt tttagttaag atagcttttg aagctacacc
    31741 atatggaagt atacatgaat ttatatttaa gtttttacaa atgccattat taaaattagg
    31801 aaatagttta ggtgctatgg caatcgctta tatattctta catttattct ggttctttgg
    31861 aataaatgga agtagtgttg ttggggctgt gtataatcca atattaaaaa ttctatcagc
    31921 tgaaaactta gctgcttttc aagctggttc aaaaatacca aacataataa caggtcaatt
    31981 ccaagatatg tttgcgacat ttggtggagc aggtagtaca ctatcattag tcatagctat
    32041 gttattaata tgtaaaagta aacgtataaa gtcaatggga aaactatcaa ttttaccagg
    32101 aatatttggt ataaatgagc cattgatatt tggtctacca ataatgctta acccaatact
    32161 attgatacca tttgcaatag ttccaacaat aaatataata atagcttact tctgtatgtc
    32221 agcaggatta gtgcctctta caaatggagt tcagttaccg tggacaactc caattatatt
    32281 ctctggtttt ttaacaacag gatggcaagg tgcagtctta caattagtac ttcttatact
    32341 aggaatattt atgtatatac catttataaa aatgctagat aagcaatact tgagagaaga
    32401 aaatgaaact gttgaagagg aagatgatga tatatctttt gatgatttag tattatagga
    32461 ggaagattat gaagaaaata gttatgatat tggaccaaat acaagctgga gctggaggaa
    32521 aagagaaaag taatatacct cctgctggaa aatcaagccc attaggacca ggtgtaatga
    32581 tggagcaatt tttaaatgaa tctaaggtaa tagctacctt attttgtggg gatgaatttt
    32641 ttgtaaataa tcaagaagaa gtaacgagta agatgatagc tatggtaaaa aaattaaacc
    32701 ctgatgtagt aatctgtgga ccaagcttta attacgaaaa cttttctaag atgtcagcaa
    32761 tactgtctaa aaatataaat gataaaacag atataccagc ttttgcagct atgtcagaag
    32821 aaaatataga tgtgataaac gaatataaaa atgacatatg tatagttaag actccaaaaa
    32881 aaggtggaat tggtcttaat gattcattaa ataacatatg taaattggca aaagcaatag
    32941 caaataaaga agatataact ttgatgaaag aagagttttg ttatcaataa gagtattaat
    33001 tattagcaag tttaaatatt atactattta taataagcat acattagtaa aatctatata
    33061 atttaaggag gggaatttta acatgtgggg aatgatagcg acatggagaa tggccctaga
    33121 aggaataact gaggcatcag aacatttaga aaaaggcatg gaagcaggtg atgctgtaga
    33181 gcttgctgta agaagagttg aagactatcc attctataaa tcggttggat atggtggact
    33241 tccaaatgaa aattgtgagg tagaacttga cgctgcattt atggatggta acacattaga
    33301 tattggcgca gttgctggta taagagatta ttctaatcct gtcagcatag ctaggaagtt
    33361 aagttatgag aaggtaaata attttttagt tggaataggt gctgaagatt atgctcataa
    33421 aaatggattt gaaagaaaaa atatgttgac tgatagagcg aagttacatt ataaaaagag
    33481 aaaaaaagag actttagaca aaggattaag cccatatgct ggtcatgata ctgttggtat
    33541 gatatcttta gacaaaactg gaaaaatgtg tgcagctaca tcaacaagtg gattgtttat
    33601 gaagaaaaga ggtagaatag gagattctgc actatctggt tcaggattct atgttgatag
    33661 tagtatagga ggagctacag ctactggttt gggagaagat ttaatgaagg gatgtatatc
    33721 ttatgagata gttagactta tgaaagaagg gaagcatcca caagaagcat gtgatattgc
    33781 agtaaatgaa cttgataaac agcttatcga aagaagagga aaagctggtg atttatcatt
    33841 agttgccatg aataataaag gtgaatgggg agtagctaca aatatagctg attttacttt
    33901 ttcagtagta actaaagaag aatctcctac tgtatatatt tcaaatagag tagatggaaa
    33961 gactatacat aaggttatat caaatgagtg gatggaagca tatgaggcta gaataaaagc
    34021 accaatagaa gtaagtgagt aaagtagtgg ttacataatt aaaatagagt tttataataa
    34081 ggagattttt atgaatatca taagtaataa aatagatgag ttaaaagaag atttattaag
    34141 tgatattata gatattgtaa aaatacctag tgtcaaaggg gagtcagaaa atggcttccc
    34201 ttttggcgaa aaagtagggg aggcacttaa taaagcatta gaaatatcag aaaaattggg
    34261 atttaaggtt agaaacttgg ataattatat tggttatgca gagcatggag atagtgatga
    34321 ttatgtttgt gtaattggac atgtagatgt tgtacatgaa ggagatggtt ggaagcatca
    34381 gccttataag ggagaagaaa ctaatggaag aatttatgga cgaggagtac tagacaataa
    34441 aggacctata atgtctgcct tatatggatt atatgctatt aaagaattaa acttaaaatt
    34501 agataagaga gttagaataa tatttggtac aaatgaagaa agtggatttg aagatatacc
    34561 atattattta gaaaaagaaa aagcacctat tatgggattt acaccagatt gtaaatatcc
    34621 tgttgtatat ggtgaaaaag gcatggcaaa gattagaata aaaagtaaaa tcaattatga
    34681 agaagatgta tacctaggtt ttatagaaaa tatgtctgaa aatgtgcttg ttacatataa
    34741 agagctgaat atagaaaata gtgatactat attagatata aaggtaaaat acgattttag
    34801 ttataaattg aaagatgtat tggatgaaat aaaagctagt tttccaaata gtatcgatat
    34861 agaggtaatt tctaatttta atcctgtata ttttgataaa gagagtaatc ttgttaaaaa
    34921 gcttcagcta gcttatgaaa gggttacatc attagatgga actcccgtaa caactaatgg
    34981 aggtacgtat gcaaaagtaa tgccaaatat agttccgttt ggaccttcat ttccaggaca
    35041 aaaaggaata gctcataatc ctgatgaata catggatata gaagatataa tattaaatgc
    35101 aaagatattt gcaaatgcaa tatatgaatt agcaaaggag tagttatgtt agaaataata
    35161 ggaatgtcag tagaagacgc taaaattata gaagattgtg gtgcagatag aatagagtta
    35221 gttagtgctt taactgaagg tggattgaca ccaagttttg gtcttataga aagtgttgtt
    35281 aacagtgtaa agatacctgt gaacgtaatg ataagacatc atgcgaaaag ttttgtatac
    35341 agtaaagaag atataagtat aatgcaaaaa gatataggtg tggttaaaga gattggtgct
    35401 aatggagttg tatttggtgt attggataaa aacaataata tagatgagaa aaatctaaat
    35461 gttttattga aatgttgtga taatcttgat gttacatttc atagagccat agatgaatca
    35521 aatacaatag atagtgttaa aattttgaag gattatgata aaattacgaa tatattaaca
    35581 tcaggaggga aaggaagtat agttgataac atacaaatga taaagaatat gatgcttagt
    35641 tctaatcaca taaaaattct tttaggtgga ggtcttaatt ttaataatat agaaaagata
    35701 aaggaattga ctaaggcaag taattttcat tttggtacag cgattagaat aaataacagt
    35761 ccttttgaag atatagatag acaaaagctt aaacaactcg taaatataat ttcaagatag
    35821 tatatgaata taaaatactt agtttaaata aagagagtaa gttaattata atttgggtat
    35881 atgaatgtta ataggtatta aatatgaaat tattgttgag tatgctttat aacttttaag
    35941 tagttttaaa tataaataat gaaagaaaag atagattatg gaggttttag agggtttata
    36001 tttattaaaa aattataaag gtatattggc atataataca cataatttcc taaaattacc
    36061 atcttatgac atgaattcac atattaataa acaattaatg gagatttttg tggatagaaa
    36121 taggagtaaa aatagcttta aataaacaaa aacaagagtt attaacagtt ttatccacat
    36181 tatccacagg tgtttgtaat aatattaatc cacataagta tcaatgtaac taaaaatgat
    36241 aaataattct atcaattgaa tagaaaaaat cataaaagta aataataaaa agaggattat
    36301 gagagttcgt gtagaatata ttattaaagt ataaattttc ttatactggc ataattgaag
    36361 ggagatgtat ttatgaacat aattatatct ggaaaacaaa tcgaattaac tgatgcaata
    36421 aaaaataaaa tcgaaactaa actaagtaag ttagataatt acattcatcc agacactgat
    36481 gtaaaagtta cagtaagtgc gagaaaagca agacaaaaaa tagaagtaac aatagctact
    36541 gtaaatggtc ctataattag agcagaagat atgcaggaaa atttatacac agctatagat
    36601 gttgtatatg ataaattaag taaacaatta aaaaaatata aaaagagatt acaagataaa
    36661 cataaagaca acaagagtat aagattccaa gatgcagaga taaatctagc tgatgaacaa
    36721 gaggattatg gggatgaaaa tcaagaatta gtaattcaaa gacgtaagaa atttagtgtt
    36781 aagccaatga gtgaagaaga agctgtatta cagatggaat taataggaca tgatttttat
    36841 atgttcaaga acatagattc agatgaaata gcagtagttt ataagcgtaa taatggtgga
    36901 tatggtataa tagaacatga ataaagcaat ttagatttaa tcatattagc tatcgataaa
    36961 taaattatcg atagcttttt aaattaatat taaaagtata gtttttatgg taaaatgaat
    37021 aatagtacaa taaagaacga ggagagatgt aaaatatgag ctttatggat aatttattca
    37081 acatggcaga taaaaaagaa ttaaaaaagt tcaataaaac tgttgatata atagattcat
    37141 tagaacctaa atttgaatct atggcagact cggaacttaa aaatatgaca aatatattta
    37201 aagaaagatt agcaaatggt gaaagtatag atgatatact tccagaagct tttgcagtag
    37261 ttagagaagt ttctaagaga gtgttaggac ttagacacta cagagttcaa atgattggag
    37321 gtatagtact acatcaagga agaatagcag aaatgaaaac aggtgaaggt aaaactttgg
    37381 ttgcaactgc tcctgtttat ttgaatgcgc ttactggaaa aggtgtacat gttgtaacag
    37441 taaatgatta ccttgcaaaa cgtgatagag accaaatggc aaaaatctat gagtttttag
    37501 gaatgagtgt aggcgttatt atacacggtc aaaatccaaa agttagaaaa gaacaatatg
    37561 attgtgatat aacttatggt acaaataatg aatatggatt tgactatcta aaggacaata
    37621 tggtaataca caaagagcaa agagttcaaa gaggattaaa ttatgctata gtggatgagg
    37681 ttgactctat actaatagat gaggctagaa caccacttat catatctgga cctggagaca
    37741 aatcaactca cttatattca gatgcaaaca catttgtttt aaccttaaaa ccagatgatt
    37801 atgaattaga agaaaaagat aaggctgtat ctctaacagc atcgggtata caaaaagcag
    37861 aagtgtattt taatgttgat aatataacag atatatctca tacagaatta taccatcata
    37921 taaatcaagc tttaagagca catgtaataa tgaagaaaga tgttgattat gttgctaaag
    37981 atggagaaat agtaatagta gatgagttca caggtagact tatgtttggt agaagatatt
    38041 cagaaggttt acatcaagca atagaggcta aagaaggtct taaaatacaa agagaatcta
    38101 aaacactagc tactgtaaca ttccaaaatt actttagaat gtacaaaaaa ctttctggta
    38161 tgactggtac agcaaaaaca gaagaagaag agtttaaagc aatctacaaa atggatgttt
    38221 tccaagtacc tactaataag cttatgataa gggaagactt accagactgt gtatacaaaa
    38281 gtgaaatagg taaatttaat gctgtagcac aagaaataat tgaaaggcac aaagtcaatc
    38341 aaccaatact tgtaggtaca gtatcaatag aaaaatcaga attattatca caaatactaa
    38401 agaaaaaggg aataaagcac gaggtattaa atgctaagca tcatgataaa gaggcagaaa
    38461 taatagcaca agctggtaga cttggagctg ttacaatagc tactaatatg gctggtcgtg
    38521 gtacagatat agttctaggt ggaaatccag actttttaac taagagagaa atgagaagaa
    38581 atggatttaa agaagaaata gtaaatagag tagatactcc aatagaaggt atacctgtaa
    38641 aaggtaatga aattctattt gaagctagag aagagtatga aaaactattt gaaaagttta
    38701 agcaacaaac acaagaagaa caaaaacaag ttgtagaagc aggtggactt gctataatag
    38761 gtacagaaag acatgaatct cgaagaatag ataaccagtt gagaggtcgt gctggacgtc
    38821 aaggtgaccc agggagttca agattctata taggtcttga tgatgacctt atgagattgt
    38881 ttggtagtga tagaatatct ggtattgtag ataaaatagg tcttgaagaa gacatgccga
    38941 tagaacatag aatattatct aagtctattg aaggagcaca aaagaaagtc gaaggtaaaa
    39001 actttggaat aagaaagcat gtacttcaat atgatgatgt tatgaataaa caaagagaaa
    39061 taatatatgc agagagaaaa cgtgtattag aaggtgaaga tttacaagaa caaatacaat
    39121 caatgactca ttctataata gaagaagcag ttactcttta tacacaagat aaaggatttg
    39181 atgaagaagg attcaaagaa catatgtata atttgttctt gccaaaaggt agcatagaaa
    39241 taccagaaat agaaaaactt aatccagttg aaataacaga aaaagtttat gaaatagcta
    39301 tgaagatata tacttcaaaa gaagaacaag ttggctatga gagaatgaga gaagttgaga
    39361 gagtaatctt acttcaagct gttgataacc attggataga ccatatagat gctatggacc
    39421 aattacgcca aggtattggt cttcgtgctg taggtcagca agacccagtt attgcttata
    39481 aaatggaagg ttttgatatg tttgatgaaa tgaataaaca tatcaaagaa gatactgtaa
    39541 gatatttatt taatataaca atagaaactc cagtggaaag aaaagcagtt gtagatgttg
    39601 aaaatctatc ttctccatca gatggaacac ttccaacaag taaaactgtt aaaaaagatg
    39661 aaaaggttgg aagaaatgac ttatgccctt gtggaagtgg taaaaaatat aaaaactgtt
    39721 gtggaagata atctcggagg attaaatgtt aaagttacaa gagtatagac atagtatgga
    39781 gcagatggct tcaaatttag aagaattgag ggtttctctt tgacatagct tcattgatga
    39841 aaaatataca aattaatgaa gaaaagatga atcaacaaga tttttggaat gataatgaag
    39901 tcgctcaaag agtacttcaa gaaaataaat ctttaaaaga gacattagaa gaatatgaaa
    39961 gcttaaaaag cttattagaa gatatagaag tattaattga aataggttta gaagaagata
    40021 atgattctgt agaaagagat atagaaaagt ccatagaatc aatggaagaa aaattatctg
    40081 aaatgaaaat aaagactctt ctaaatggag agtatgataa aaataatgct atattatcta
    40141 taaatgctgg tactggtggc ttagatgctc aagattgggc tcaaatgctt ttgagaatgt
    40201 atataagatg gtcagaaagt aagggttata aagttaagct tttagatata atatcagacc
    40261 ctgaagcagg gataaagaca gctacaattc ttgtagaagg aacaaatgct tatgggtatt
    40321 taaagagtga aaaaggagtt catagattag tgagaatatc tccatttgac ccatcaggaa
    40381 aaagacatac ttcatttgca tctatagatg taacaccaga gttagatgaa aatatagaag
    40441 tagaaattaa tccatcagat ttaaagatag acacatatag agcttctgga gctggagggc
    40501 aacatgtaaa tacgactgat tcagcagtta gaataacaca tatccctact ggtgtagtag
    40561 ttcagtgcca aaatgaaagg tctcagcatc taaataagga cagagctatg agacttttaa
    40621 tggcgaaatt gatagaatta aaagagttag agcaaaagga aaaaatagaa gatatacaag
    40681 gcaaatactc acaaataact tggggtagtc aaattaggtc atatgttttt caaccatata
    40741 aattggttaa agaccataga acaaatgctg agtttggaaa tgtagatagt gtaatgaatg
    40801 gaaatataga cttgtttatt aatgaatact taaaaatgaa taaaatagtt taataaatat
    40861 gcactgtaat taagatatat gtataagaag gttagtgctt aatatgcact tacagcactt
    40921 aggctgagga cgataaccct cagccttcgt tctgttttgt tatacttatg aaaaactaac
    40981 attaggagtg aataaattgg atataaatca aatcttaaaa aaagagttta atcttagaga
    41041 tgaacaaata aataatacat taaaacttat tgatgaagga aatacaatac catttatagc
    41101 tagatataga aaagaaatga ctggcgaaat gagtgatgtt acactaagag aattttatga
    41161 aaaattaatg tatttgagaa atcttcaaag tagaaaagat gatgtagtta gactaataga
    41221 tgaacaaggg aaattaacag atgaaataac acaaaatata gaaaaagcaa aaacattaca
    41281 agaagtagaa gatatatatg ctccatataa acaaaagaaa agaactagag caacaatagc
    41341 aaaagaaaaa ggattagaaa atttagcatt gtcaatacta gagaataatt tagataatat
    41401 agaaatagag gcaaagaatt atcttgatga agagaaagaa gttctttcta ttgaagatgc
    41461 tctaaaaggt gctagagata taattgcaga actagtctca gatgatgcta agattagaaa
    41521 gtatataaga gaattagctt taagagaagg tatgatagtt agcaaaagtg ctactgatga
    41581 gaaatcggtt tatgatatgt attatgatta tagcgaagca gtaaaaagta tggctccaca
    41641 tagagttttg gcaataaaca gaggagaaaa agaaagcttc ctaaaggtta agttggaaat
    41701 aaataatgat aaagttttaa attacataat aaacgaatat gtaaatgata aaaatttcaa
    41761 aaataaagaa gaaatcgtaa gttcaataga agattcttat aaaagattaa ttttcccatc
    41821 aatagaaaga gaaataagaa atcatttaac agaaatagct caagaaagag ctataagtgt
    41881 atttggaaag aatgttaaaa gtttattgct tcaaccacca gttaaagaca aagtagttat
    41941 gggatttgac cctgcattta gaactggatg taaaatagct gtagtagata aaaatggtaa
    42001 actactagat tatacaacag tatatccaac agaccctcaa aatgatgtag agggagcaaa
    42061 gaaagtttta aaaggattga ttgaaaaata cgatatagat ataatttcaa ttggaaatgg
    42121 tactgcatct agagaatcag aaacttttgt atcagaaatg ataaaagaaa tagatagcga
    42181 agtgcagtat gtgatagtta gtgaagcagg agcatctgtt tattcagcat ctgaacttgc
    42241 aaatgaggaa catccagata taaatgtatc aataagagga gctatatcta tagctagaag
    42301 attacaagac ccattagcag agcttgtaaa aatagaccct aaaagtattg gtgttggtca
    42361 atatcagcat gatttaaaca aaaagagatt agaagaagta ctagatggag ttgttgaaga
    42421 ttctgtaaat agtgttggag tagatttaaa tactgcatca tactccctac tagaacatgt
    42481 tgcaggaata agtaaagcta tagcaaaaaa tataatagca tatagagaag aaaatggaga
    42541 ttttacgtca agagcacaat tgaaaaaagt aaaaagacta ggacctcaag catttactca
    42601 atgtgctgga tttatgagaa tcttagaggg taaaaatcca ctagataata caggtgtgca
    42661 tcctgaaagt tatgatatat gtaaaaaaat gattgagata attggatatt ctttagatga
    42721 tgtaaagaat aagaatatag gtgaaataga tgaaaaaata aaagaaattg gcttgaggga
    42781 attaagtgaa aaactggaag taggacaagt tacgttaaaa gatatcatag ctgaaatcaa
    42841 aaaaccagga agagacccaa gagaagaagg tataaaacct atacttagaa ctgatgtctt
    42901 aaaaattgaa gatatacaag agggtatgac tttaaaaggt acaataagaa atgttgtaga
    42961 ctttggtgca tttgtagata ttggaataaa aaatgacgga ttagttcata aatcagaaat
    43021 gagtaatagt tttgtgaaag accctatgag tattgttaca gtaggtgata tagtagatgt
    43081 aaaagtcatt ggaattgact taaacaaaaa aagagttgcc ttatcaatga aaaaatagat
    43141 aagtttatgt atggttatag tacttagatt ctatatttgt aaataagatt actcgagtgt
    43201 ataaatgtta aaaatttgta aaagtatata gtaagaaaat atattaaaat aagaacgata
    43261 gtcttgaaaa tcaggaggaa aatgaatgat ttttataaaa aatggtaaaa taaataccat
    43321 aacaaatggg ataattcatg gagatatact tatagatgaa ggaaaaataa tagaaattgg
    43381 agaagatttg atagctcctt tagatgtaga ggtaatagat gctagtaata aacttgtgtt
    43441 tcctggattt atagatgctc atactcactt aggtttatgg gaagatggta tagggtttga
    43501 aggagcagat ggaaatgaag agactgaccc aataacacca caattaaatc ctatagatgg
    43561 aattaatcca atggatagaa cttttaaaga agcttttgaa ggtggaataa cttctgtttg
    43621 tacaacccct ggaagtgcaa atgttatggg tggtcaatgt atagctataa agacatgtgg
    43681 aaaaagaatt gataaaatgg taataaaaaa tccagttgca tctaaaattg cttttggaga
    43741 aaatccaaag agctgttatg gtcaggatga taaatctcct caaactagaa tggctatagc
    43801 tgctttactt agagaaaacc taaaaaaagc agaagaatat ttagaggata ttgatatgta
    43861 tgagagtcat gatgatgaag actgtgaaaa acctgaatat gatataaaaa tggaaagttt
    43921 aataccagtt ttaagaagag aaattccttt taaggcacat gctcatagag cagatgatat
    43981 gtttacagca ataagaattg caaaagaatt taatttaaag cttacattag accattgtac
    44041 agaaggtcat cttattgtag atgaattagt ggaagaaggg tttcctgtaa tagtagggcc
    44101 atctttgtca gaaaggtcta aatttgagct tagaaatttg acatttaata cagcaggaat
    44161 actttcaaat gcaggtcttg atgtatgtat aatgacagac catccagtaa taccagttca
    44221 atatcttcca atatgtgcag gtattgcagt aaaacatggt atgaaagaag aaaaagcaat
    44281 agaatcaatt acgataaatc cagctaaggc tttaggaata gaagatagag taggctctat
    44341 agaagttggt aaagatgcag acctagtaat ttgggataat tctccactag agattcaaag
    44401 taatgtactt tacactataa taaatggcaa agtagtgtat gagaaaaaat aacttgacaa
    44461 ttattaaaaa attaactaat ataagagtgt aaggaaaatt aaaaaatcaa agaagatctt
    44521 cggggcaggg tgaaattccc taccggcggt atagcccgcg aactacttag gtggttgatt
    44581 tggtgagatt ccaaagccga cagtaaagtc tggatgagag aagatattta tggaagataa
    44641 ataagtttat tttagtttgt ttaaactata tccataaaaa ctcgaagata gggtcttcga
    44701 gttttttgtt tttcctaaaa aatataaaca tattgattag ggggaaaata attatgcaaa
    44761 acacagcaaa aagaggcaat atgatttcaa caagaacttt agtagtaatg tcaattttat
    44821 ctgcaatatc ttatttatta atgtttattc aagcaccaat accaggtata tttccagatt
    44881 tcttaaaaat tgacttatca gatattccag caatattcgg aggaatgtct ctaggaccat
    44941 tagttggatt tggaatagtt gtagtaaaaa atgtgttaca agcaataaca gcaacaacaa
    45001 ctggaggaat aggagaattt gcaaatatat taattggtgg ttcttatgta atgatacttt
    45061 gttattcata taagagaagt ggagatttaa aaggtgtact gattggtttt gtattaggaa
    45121 caatatctat gactataatt ggttcattag taaattattt tgtaatgttg ccactttatg
    45181 gtcaacttat gggactagat gctataatag gtttaggttc agctataaat cctcaagttc
    45241 atgatttatt cacttttgta atttggatga tagctccatt taatgtgctg aaggctgtta
    45301 taatatcttt agtaacattg ccactttata aaaaaatggg aaatataata aagaaataat
    45361 tagacaagaa aatataaaat taaatgtatt gaatagccat aatttattta taacttcagt
    45421 cctatattgt gattgatata ttaaatatat tatggcttta ttaatttatc aaaaaatgta
    45481 tataaaataa gaaatattta gacaaattta aattttaaaa taaaggaaga attaaaacga
    45541 ttaactatta aaatatgaaa aaggtatcta caatatacag agcgaattta taataaacaa
    45601 aaaataaagt tattattaaa aaactataaa gattaataat caaactttta ataataacta
    45661 atttaataat gataggggtg tatattcatg catttatcta aaaaaataaa aaaattattt
    45721 ttagatgata aagggtatta ttttaatagt aattggaaag atattcatat tggtatttat
    45781 gatacaaaat taggagattc tttaaagtat atcactaatg aatatattga aaatatggaa
    45841 agggtaaaat acgattatcg tgaattaaaa aatatagaaa atcaaactga tggtatgtgt
    45901 attttagcaa taaggcagaa ttacaaggca ttagagtatg taaaaaatca aaccgaagaa
    45961 ttatgtttag aagcaataaa gtataattat aaagcacttg aatatgtaaa agaacaaaca
    46021 gaatacttgt gtcttgaagc tataaaaaaa gattgtaatg cacttaagta tgtacgaaat
    46081 aaaacagaag ggcttattat aaaagcaata agtcattctt ccaatataga tgttgtaagt
    46141 atactaaagg ctttagagac tcaaacaaga aggatatgtt tagaagcaat taaaaaagat
    46201 ggcaggtgtc ttgcatacgt tagagaacag agtgaagaat tatgtataga ggccattaag
    46261 caaaattata aagcattaaa atatgtaaaa aatcaaacgg aaaaaatgtg tatagaatcc
    46321 gtaagacaaa atggtatggc attacaatat gtaaataaac aaactgataa aatatgtata
    46381 gaagctgtca aacaagatgg aagaagtcta caatttgtca acaataagac agaagaaata
    46441 tgtataaatg ctataagata tttaaataaa aaatataata ttaaagatgt actaagttac
    46501 atagataagt atacagaaga tatatgtata gagattgtaa gacaaaatgg aaaaatgctt
    46561 atgtatataa aaaatcaaac agaaaaaatg tgtattgaag cagtaaaaga gaactataag
    46621 tctcttaagt atgtaaaaga gcaatctgag agaatatgta aagaagcatt gaagcaaaac
    46681 cataaagcaa aagagtatgt aaaaattgct attgatgatt gtatataagg tgtagataca
    46741 gccatcaata gtgaaagata aaaaaagata aagacaagta ctttataata atctaggctt
    46801 atactataat taattaagca gtgatataaa ttcacatgac gattatatca aaatggagat
    46861 gaattgatgg caaaaatata tttagaaaat gaaaataaaa ctagagaaat aggatataaa
    46921 ttaggtaaac ttttaaaaga aggcagtgtt atctgtttag taggagattt aggagctggt
    46981 aaaactacaa tgacacaaag cttggcagat tcattaggga tagaagatta tataacaagt
    47041 cctactttta ctataataaa tgaatatgaa ggaaaaatac ctttgtatca ttttgatgtt
    47101 tatagaatag gtagtagtga tgaaatgtat gatattggtt atgatgaata tgtaaattca
    47161 aatggaatct gtataataga atgggctaat ctaatagaag atatacttcc aaaagaatat
    47221 ttgaatatag aattgagata taaagatgaa ggaagagaaa tgatattaac tccaaaagga
    47281 gagttttata aagagatagt tgaggagttg attaaataat gaaaatacta ggtatggata
    47341 cgtcttctat ggcagcaagt gtagcagttg ttgaagatga taacttaata tgtgagttta
    47401 cagtaaacaa caaaaaaact cattcacaaa agcttatgcc aatgatagaa aatatgttga
    47461 gtatgagtga tttaagtata aaagatatgg atttattagc tgtatgtata ggtccaggtt
    47521 cgtttacagg acttagaata ggtatggcta cagtaaaagc tatggcccat gtaaataata
    47581 taccaataat agcagtaaat tctttggaat ctctagcaaa taacataaat ttctgtgata
    47641 gaaagatatg ttgtatatta gatgcgcaga aaaatcaagt ttattcagct aaatacaagt
    47701 ttgaaaatgg agagatgata gaattagatg gtgttgatgt tgtagagttt gatgctttag
    47761 tagatgaaat tgtatcaact aatgaagaat ttataatagt tggagaagct gtatacaaat
    47821 ataaagacaa gttagagaat ataaaaaata taaaaatacc ttcaccagct aataatgtat
    47881 ctaacgcagg aagcttatgc tctttagcat taaataaata taataaaaat atagatgtac
    47941 atacttgtta tacgataaat cctatgtata tcagaaaatc tcaagctgaa gtacaatatg
    48001 atgaaaaaat gaagaggcta aataatggaa gataatacaa aactaatagt agatgatata
    48061 aaaatagaag aaatgactac agaagatata gatgaagttt ttgaagtaga aaaaaattgt
    48121 tttgaagatt attggtcaaa agagtctttt agaaaagagt tgtctaatga agtagcaagg
    48181 tatatagtag ctaagttaaa tggaaaaatt gtcggatatg tgggaatttg gcttatactt
    48241 gatgaagggc atataaataa tgtggctgtt catagtgact atagagggaa aaaaataggg
    48301 gacaagttga taaaaggcat agttgattta tgtaaagata ataatattgc atctatgaca
    48361 ttagaagtta gagcatcaaa taaaatagca caaaatttat atagaaaata tggatttaaa
    48421 atgggtggaa taagaaaaga atactacagt gataataaag aagatgcaat tataatgtgg
    48481 aaccaattaa aagaggtgta gagtttatga gtgatataat aacattagct atagagagta
    48541 gttgtgacga aacagctgca tcagttttaa aaaatggtag agaagtactt tcaaacataa
    48601 tctctactca aatcgagaca cataaaaaat ttggtggtgt agttccagaa gtggcctcaa
    48661 gaaaacatgt ggaaaatatt gatatagttg ttcaagaagc tttagacaaa gcaaatatag
    48721 gttttaatga tatagaccat atcgcagtta catatggacc tgggctagta ggtgctttat
    48781 tggttggtct atcttatgct aaagcacttg catatacttt gaatattcca cttgtaggag
    48841 taaatcatat agaagggcat ctaagtgcaa actatataga gcataaggat ttaaaacctc
    48901 cttttataac attaatagta tctggaggtc atactcactt ggttgaagta aaagattatg
    48961 gcaagtatga aattttagga aaaacaagag atgatgcatc tggagaagca tttgataaga
    49021 tttcaagagc tatgaattta ggctatccag gaggtcctat tattgataat ctggccaaga
    49081 atggaaataa acatgctata gaatttccaa gagcctattt agaagaagat agctatgatt
    49141 ttagttttag tggattaaaa tcctctgtat taaattatct aaatggaaaa agaatgaaaa
    49201 atgaagaaat agtagttgaa gatgtagcag catctttcca agaggctgta gtagaggttt
    49261 tatctactaa agcactaaaa gcagtaaaag acaaaggata caatatcata actctttctg
    49321 gtggggttgc ttctaattcg gggcttagag ctaaaataac agagcttgct aaagacaatg
    49381 gtattactgt taagtatcct cctctaattt tatgcacaga taatgcagct atgatagggt
    49441 gtgcaggata ttataatttt ataaatggga aaacgcatga tatgagttta aatgcagttc
    49501 caaatttaaa gataaatcag tagagttaga tgaatttgta aatataaaag tattgtttca
    49561 aaaaagtaag tagaagtgaa attaaatata ataaaaataa atatagtata tattaaaact
    49621 tgaagtaaaa ctatttataa tctttatatt ccaatgaatt gcaacaaatt ttaggatata
    49681 cagattgtct ttggcttaga tttgcttcaa gtttaatttt ttctatagaa agattatttt
    49741 aaaaagtggg taatataccc ttttttttca ttcttaaaaa gttttatact aattatagaa
    49801 agattaagga ggggaagaaa tgagtcaaag taaagaagac aaaataagaa gtattttgga
    49861 agcaaaaaat attaaatcaa attttcaaaa taaagaaaat ttaagtgaat ttaatgaaaa
    49921 aaaagcaagt aaaagagcag aagacttatt agatgtatat tataatacat tatctactgc
    49981 tgatatggaa tttccatatt ggtataatag agaatataga aaatcagatg gtgatatacc
    50041 agtagttaga agagctaaag ctcttaaagc tgctttttca catatgacac caaatataat
    50101 acctggtgag aaaatagtaa tgcaaaagac acgccattat agaggttctt ttccaatgcc
    50161 atgggtaagt gaaagtttct ttgttgctca aggagaacaa atgagagaag aggcaaagaa
    50221 attagccagt aacacagctg atgaacttac aaaatttggg tctggtggag gaaatgttac
    50281 tgaaagtttt ggaaatgtcg tttcaatagc tggtaaattc ggaatgagaa aagaagaagt
    50341 acctgtactt gtaaaaatgg caaaggaatg ggttggaaag tctgttgaag atttaggttt
    50401 tcactatgaa aaaatgatgc cagattatga tttaaaagaa aacctaatga gtacacttat
    50461 atgcatgttt gattcagggt atacacttcc tcaaggtaga gaagttataa attattttta
    50521 tcctttaaat tatggattag atggaattat agaaatggca aaagaatgta aaaaggcagt
    50581 tgcaggaaat gcatctggag atgggcttat tggtatggac cgtctatatt tttatgaggc
    50641 tgttattcaa gttattgaag gattacaaac ttggatttta aattatgcaa aacatgcaaa
    50701 atatttagaa agtatagaga cagatttaga agctaaaaaa gaatactcag atttagtgca
    50761 gatattagaa catattgcac ataaacaacc tcgtacattt agggaagctc ttcagttgac
    50821 ttatacaatt catatagcat cagtaaatga ggatgctata tctggtatgt ctataggacg
    50881 ttttggtcaa attttatatc cttggtatga acaagatata gaaaaaggac taattacaaa
    50941 agaagaggtt atcgaattat tagagcttta tagaataaaa atcacttgta ttgactgttt
    51001 tgcttcagcg ggcgtaaatg gaggagtact atcaggcaat acatttaata ctttatctat
    51061 aggtggatta aaagaagatg gttctacagg agctaatgaa ctagaagagt tattattaga
    51121 agcaagtatg agatgtagaa ctcctcaacc tagtttaact atgctatatg atgaaaagct
    51181 tccagaagat ttcttaatga aagctgctga atgtacaaag cttggttctg gttatccagc
    51241 atgggtaaac aactcaaatg gaacaacatt tatgatgaaa caatttgctg atgaaggtat
    51301 gactgttgaa gaagcaagag catttgcatt aggtggatgt ttggaaacgt ctccagggtg
    51361 ttggaaacag ttaactttaa acggaaaaac atactctatt gcaggtggag caggtcaatc
    51421 tgctggctct ggagttcact ttatagctaa tccaaaaatt ttagaacttg ttcttatgaa
    51481 tggtaaagac tatcgtatga atatacaagt atttgagcct cataataagc cattagatac
    51541 ttatgaagaa gtcatagaag tatttaaaga ttattataaa caagcaataa atgttttaga
    51601 aagagcaaat aacattgagt tagatatatg gagaaaattt gatacttcta taataaattc
    51661 actactaaag ccagactgtt tagacaaagg tcaacatata ggaaatatgg gatatcgtta
    51721 taatgcaaca ttaaacgtag aaacttgtgg tactgttact atggtcaatt catttgcagc
    51781 tcttaagaaa cttgtatatg atgacaaagc atttacaata gaggaaatga aggatgccat
    51841 attaaataat tttggattta aagatgcatt agaagtagga aattattcta tggcggacca
    51901 agtaaaagta gataagactg gtaaatatga tgctatttat aaggcctgtc ttgatgcacc
    51961 taaatatgga aataatgatt tgtatgcaga taatattctt aaaaactatg aggtatggtt
    52021 atcaaaagta tgtgaagaag cacaatcttt atatgctaag aagatgtacc cttgccaaat
    52081 atctgtttct acacatgggc cacagggagc tgctaccttg gctactccag atggtagact
    52141 aagtggaaca acatattcag atggttcagt ctctgcatat gcaggaacag ataaaaatgg
    52201 agtatatgca ttatttgaat ctgcaactat ttgggaccaa gcagtagttc aaaattctca
    52261 gatgaattta aaacttcatc caactactat aaaaggacaa caaggaacta aaaaattatt
    52321 agatttaaca agaagttatt taagaaaagg tgggttccat attcaatata atgttgtaga
    52381 ttcagaaaca ttaaaagatg cacaaaaaaa tcctgacaat tatcgtcaat taatggtacg
    52441 tgttgctggg tttactcaat attggtgtga attaggtaaa ccaatacaag atgaagtaat
    52501 tgctagaaca gagtatgaag gggtgtaaaa tatgagaaag catagtgatt gtatgaattt
    52561 ttgtgcagta gatgcaacca aaggaatttg tagattatca aaacaaatga ttaatttaga
    52621 tgatgcagca tgtccagaga taaaagtaat gccaaaatgt aaaaattgta aaaattttgt
    52681 tgaagctaat gatgaaggta taggcaaatg tgttggccta gagaaagaag actgggtata
    52741 ttcaacattg aatgcaatta cttgtgaagg acatgtgttt aatgagtagt caaaagcaat
    52801 tagaaggcat gatttttgat gtacaaagct tttcagttca tgatggtcca ggttgtagaa
    52861 caactgtatt tttaaatgga tgtccactga gttgtaaatg gtgtgcaaat ccagaaagtt
    52921 ggactgtaag accacatatg atgtttagtg aattatcttg tcaatatgaa aatggatgta
    52981 ctgtatgtca tggtaagtgt aaaaatggtg cattgagctt taatcttgat aataagccag
    53041 ttatagattg gaacatctgt aaggactgtg aaagttttga atgcgtcaac tcatgttatt
    53101 ataatgcgtt taaattatgt gcaaaacctt acactgtaga tgaacttgtg caggtaatta
    53161 aacgtgattc taacaattgg agaagtaatg gaggagtaac atttagtgga ggtgagccac
    53221 tacttcagca tgaattttta catgaagtat tattaaagtg tcatgaggta aatatacaca
    53281 ctgccattga aacgagtgca tgtgtatcaa atgaagtttt taataaaata tttaacgata
    53341 ttgattttgc atttattgat ataaagcata tggatagaga aaaacacaaa gaacaaacag
    53401 gtgtgtataa tgatttaata ttagaaaata tatcaaacct tgcaaattct gattggaatg
    53461 gaagattagt acttagagta ccagttatct ctgggtttaa tgatagtgat gaaaatataa
    53521 gtgatattat atcttttatg cacaaaaata atttggtaga aattaatcta ttaccatttc
    53581 acagattagg agaatcaaaa tggattcaat taggcaagga atatgagtat tctgataagg
    53641 gtgatgttga tgaaggtcat ctagaagaat tacaagatat atttttggat aatggtatag
    53701 cttgttatgt tggccatgag acagctttct aaaattaaat acaagtttta attaaaaaag
    53761 gatgttacac taaaagctag agttacatcc ttttttatgt ggtttttatg tagaaataat
    53821 taagtaaagt tttatatgtt ttatatattg tttatattgc tttatgtcca taaatattgc
    53881 tttaaatata ctttatatat tttttatagt ttaaattaca gttagagaat atattacgtt
    53941 tacttcattg aagcagaagt tttgtggtaa aatactacta tgaaaaaatt taatagaata
    54001 tattttagaa acaactaaaa ataatagtta ggaggaagac atctatatga acaaatcatg
    54061 gagcaacttg attattaaga ataaagacag aaaagtacgt tcagggtgga ttattatagc
    54121 tgttatggct accttttaca tacttcagta ttatttaagc atgatacttg tggaaataat
    54181 aagaaaaatc ctggttgcta caggtgacat taatttaaaa acaaactatt tttcagaata
    54241 tgctaattgg ttaaatgatg ttgggttaca gattgtattt caaattctaa cagattcact
    54301 tatgattatt attcctataa ttgtatggag atttattatg aaaaatccta ttagtgaaat
    54361 gggattacat tcttatagaa ttaagaaaaa agaaggatat gtaggaatgt tattaggaat
    54421 atttaattgt acagtaatct ttattataac aataacaatt ggtggtggtc atgttacttc
    54481 atgggtacca aaaatttcac ctttaacagt ttcttggata ctggtcttta ttttagttgc
    54541 ttttgcagaa gaaattttaa atcgtggttt ttttatggca gttttacgaa gatgtaaaaa
    54601 tatttatttt ataatgattg ttccatctgt tatttttggg ttgattcata tatggaatcc
    54661 tgatgttact tttttgtctg taattaatat tataattatt gggattcttt tttcatatat
    54721 gtttataaaa tcgtcgaata tatggatgtg tataggttat cattttgcat ggaatgtatt
    54781 tcaggggatt atatatggta tgcctgtaag tggacttcaa gttccaggga ttataactac
    54841 acaaatcact catggtaatc tattaaatgg aggaatgttt ggtattgaag gtggaatttt
    54901 gactactttt gttaatctac ttagctttat atttgtatgg tattactata gagattctaa
    54961 gtatgatttt gttagtgata aagtaaatgt gaccaatatc aagaattagt tgattataat
    55021 aaattttaat aatatcttct aagcttaaag tattctgtag gattgttgga aatttgcaaa
    55081 aatataaaaa taacttggat attctattta ctccaagtta tttttatatt cttttgtaaa
    55141 tagaaatgga acataaaaaa ttaaaacaac catagatact attagtatat catggtaagt
    55201 gatagttgat tctttagaat ttgtgataag aaaagcacta ttatttaaaa catgaattat
    55261 agcacaaaac cagatattct tagtttttat ataaagatat cctaaaaata ttgaaattcc
    55321 aactatatgt attgaacgta atattattcc taatattggc gcttcaggtg tatataatgt
    55381 aaatattagt ggtaagtgcc acaagctcca acacatacct aatattataa ctcctaactt
    55441 tttaccaaat ttatcaaaaa aaatattctg taaaaaacct ctccaggcat attcttcact
    55501 aaaaaaaata taaatagtag ttaatgatgt tattggagta aatataaatt ttatgatacc
    55561 actataatta ggttgagccc cttgtagtat tagtataaat gatgttggaa caattacaga
    55621 aatcataaag taaataatta ataaagaacc tagtttaata ttttttacag gatataaatt
    55681 ttttttattt gatgaatata ttataattga taagctactt ataaaagtta atattaggtt
    55741 tataattata aattcattat tatttattag atttaataac ttaagaacaa ttaataatga
    55801 ataaataaga aaaaataata tgattagtga ataaaattca tacatatcat tatttaatcc
    55861 ttcagtataa aactttgcaa tggcaactga agatagaggt aatatcatca tgaatgatgc
    55921 aaagttttct ggatcaataa atttattata atataacagt aaacctaatg aataagttaa
    55981 accaaagttt ataaagaaaa agataataat ttgtattttt tttcttttta tttcattttt
    56041 aataaatact gggtttagaa tatttatcca tattaatttt aagttcatta atttaatact
    56101 cc
//
LOCUS       DAMKNB010000018        54096 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.018, whole genome shotgun sequence.
ACCESSION   DAMKNB010000018 DAMKNB010000000
VERSION     DAMKNB010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 54096)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 54096)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..54096
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.018"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            37..198
                     /locus_tag="PC494_001246"
     CDS             37..198
                     /locus_tag="PC494_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3911754.1"
                     /translation="MAIVVIGIYLGFKREFSKLIGFLVVALVAVGLVFNAGGVKDVLL
                     ELFNKIIGA"
     gene            279..656
                     /locus_tag="PC494_001247"
     CDS             279..656
                     /locus_tag="PC494_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDF3911755.1"
                     /translation="MDYKVDDKNLDASMFISFVNQVWQGDYDMEQTRQALSKTLNITA
                     YDNKKLVGCLRILSDGYYFGTITELLVLPQYQKQGIGSKLLQLAKDNTPTMLYFGSQP
                     EAEKFYEKNGCQKSLQSYMINKG"
     gene            763..1059
                     /locus_tag="PC494_001248"
     CDS             763..1059
                     /locus_tag="PC494_001248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005339688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HDF3911756.1"
                     /translation="MNDIFKNMQAKIGCEYLSDLPSYKRKVWHEMKQLNLADYEEKQL
                     EDFSKYVFGMSYQTLKDVMKQQIGREEQCRKQGYWWKRKEQLTKKQHHTGSTCR"
     gene            978..1481
                     /locus_tag="PC494_001249"
     CDS             978..1481
                     /locus_tag="PC494_001249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004843359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HDF3911757.1"
                     /translation="MQETRVLVETKRTTDEETTSYWFDLPIEVAEFEEKLGVGAESGE
                     YRIIEKVLPYADEVHEHTSVYQLNKLDFMYRQLSSDMQEEYVSLLMVFENLEALYICR
                     NVITVYPDCKSMIDVARQKLMNDPTFKHLSEDCQEYYFNFEAYASHLQEHGKFLVTEH
                     GIFELPE"
     gene            1499..2002
                     /locus_tag="PC494_001250"
     CDS             1499..2002
                     /locus_tag="PC494_001250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004843360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HDF3911758.1"
                     /translation="MIDDMAVYIANLGKYNEGYLVGAWFSFPIDEEDVKEKIGLNEQY
                     EEYAVHDTDNFPIDIGEYVSIEELNEMYEMIEELPDYIVECLDEFISHYGTLEEVVEH
                     KDDIYYYPDCETMTDVAYYYIDELQALGDIPPSLQNYIDYEAYGRDLDMGGCFIETSR
                     GMCEIPY"
     gene            2123..2521
                     /locus_tag="PC494_001251"
     CDS             2123..2521
                     /locus_tag="PC494_001251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009274602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HDF3911759.1"
                     /translation="MKKIKSYTGIWNVEKVLYAINDFNLPFPVTFTQITWFVITEFII
                     ILFGDMPPLSMIEGAFLKYFGIPVALTWFMSQKTFDGKKPYSFLKSQITYALRPKITY
                     AGKAVKLHKQTLNETITAVRSVNYVPDKIY"
     gene            2499..4949
                     /locus_tag="PC494_001252"
     CDS             2499..4949
                     /locus_tag="PC494_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HDF3911760.1"
                     /translation="MFPIKYIDNNLVWNKDNEVFAYYELIPYNYSFLSAEQKFIVHDS
                     FRQLIAQSREGKIHALQIATESSIRSMQEQSKKLVTGKLREVAVQKIDEQTEALVSMI
                     GDNQVDYRFFLGFKLMVTEEQLNLKNIKKSAWLTFTEFLHEVNHTLMNDFVSMPNDEI
                     NRYMKMEKLLENKISRRFKVRRLEINDFGYLMEHLYGRDGIAYEDYEYQLPEKKLQKE
                     TLIKYYDLIRPTRCVIEESQRYLRLEHEDKESYVSYFTVNAIVGELDFPSSEIFYFQQ
                     QQFTFPVDTSMNVEIVENRKALSTVRNKKKELKDLDNHAYQAGSETSSNVVDALDSVD
                     ELETDLDQSKESMYKLSYVIRVSAPDLDELKRRCDEVKDFYDDLNVKLVRPAGDMLGL
                     HSEFLPASKRYINDYVQYVKSDFLAGLGFGATQQLGENTGIYMGYSVDTGRNVYLQPS
                     LASQGVKGTVTNALASAFVGSLGGGKSFCNNLLVYYSVLFGGQAVILDPKSERGNWKE
                     TLPEIAHEINIVNLTSDKDNAGLLDPFVIMKNVKDAESLAIDILTFLTGISSRDGEKF
                     PVLRKAVRSVTQSDSRGLLHVIDELRREDTPISRNIADHIDSFTDYDFAHLLFSDGTV
                     ENAISLDNQLNIIQVADLVLPDKDTTFEEYTTIELLSVSMLIVISTFALDFIHSDRSI
                     FKIVDLDEAWAFLNVAQGETLSNKLVRAGRAMQAGVYFVTQSAYDVSKESLKNNIGLK
                     FAFRSTDINEIKQTLEFFGIDKEDENNQKRLRDLENGQCLLQDLYGRVGVVQIHPVFE
                     ELLHAFDTRPPVQRNEVE"
     gene            4949..7144
                     /locus_tag="PC494_001253"
     CDS             4949..7144
                     /locus_tag="PC494_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HDF3911761.1"
                     /translation="MKERIQSAFTKKKMFRFLKITVFVVALSLILLSLLETVAHATGL
                     VDDTINTENLYSKYPLSNYQLDFYVDNSWAWLPWNWLDGIGKSVQYGLYCITNFVWTI
                     SLYLSNATGYVVQEAYKLDFINDMADSIGQSIQTLAGVTSSGFSTSGFYVGFLLLIIL
                     VVGIYVAYTGLIKRETSKALHAVINFVVVFILSASFIAYAPDYIKKINEFSSDISTAS
                     LDLGTKIMLPNSDSEGKDSVDLIRDSLFSIQVEQPWLLLQFGNSNAEEIGTDRVEALV
                     SVSPEDEDGKTREEIVKTEIEDNDNNILTIPQVVNRLGMVFFLLFFNLGITIFVFLLT
                     GMMLFSQILFIIFAMFLPISFLLSMIPSYESMAKQAIVRVFNTIMTRAGITLIVTVAF
                     SISSMFYNISTDYPFFMVAFLQIVCFAGIYMKLGDLMSMFSLNASDSQSMGRRIFRRP
                     YLFIRHRARRMERRMARAVSAGGISGGVAGALAGSTVSNARTTRNNPTKENRGNTTSI
                     MGQRAGSKIGAVLDTKNKVKDKANAVKENVKDMPTQTAYAVYSAKEKAKSSVSDFKRG
                     MVQEQQSRQTGRLEKQEQRKKNIANKRMELQKAQEARQARKADGSATTGATRPHERPA
                     TASKPSVEKVQEVKRPATTPTSKASEPVKTNVIKERPLSSGASDGKATQSAQPIHRQN
                     IEKVVSQETRQNYVKDRRTKVQQTQSVQKNQQTTEKNHNLVTKKGQKKK"
     gene            7141..8145
                     /locus_tag="PC494_001254"
     CDS             7141..8145
                     /locus_tag="PC494_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009243519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysozyme/C40 family peptidase"
                     /protein_id="HDF3911762.1"
                     /translation="MKLKHIALIGSLFPILFSIVLFFGVLISADSDDENSNFSSGITG
                     LNLSAEVLKHQPMVEKYAREYGISEYVNVLLAIIQVESGGTAEDVMQSSESLGLPPNS
                     LDTESSIKQGCKYFASLLSSYKNQGINDLNVAIQSYNYGGGYVGYVAGKGKKHTFTLA
                     ESFACEKSGGKKVTYTNTIAVAKNGGWRYGYGNMFYVELVNQYLTVPQVSGELAQKIM
                     NEALKYQGWKYVYGGSNPNTSFDCSGLVQWCYGKAGISLPRTAQAQYDATQHIPLSQA
                     KAGDLVFFHSTYNAGSYVTHVGIYVGNNQMYHAGDPIGYADLNSSYWQQHLIGAGRVK
                     "
     gene            8165..9067
                     /locus_tag="PC494_001255"
     CDS             8165..9067
                     /locus_tag="PC494_001255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008393312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HDF3911763.1"
                     /translation="MFKKSKKQTENVKEKKVRTVKVGTHKKTVIAFWVVLIVSVSFGV
                     YKNFTAIDMHTVHETETIQLRLTDTNGIENFVKNFAKSYYTWNNSKEAIEARTQAISG
                     YLTKELQDLNVDTIRTDIPTSSTVTDVIVWNIEQSGTDTFSATYEVDQQIKEGEQTTA
                     VKAIYTVKVHVDVDGDMVIIQNPTLAPTIEKSDYELKTPEADASVDADTINDATSFLE
                     TFFKLYPIATEKELAYYVSGNVLEPIGKDYLYSELINPVFTKDGDNVKVKVAVKFLDN
                     QTKATQVSQYELVLHKDSNWKIVK"
     gene            9211..9822
                     /locus_tag="PC494_001256"
     CDS             9211..9822
                     /locus_tag="PC494_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002591427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDF3911764.1"
                     /translation="MPKGIMLTQEQQEERREEIISVALQLIEKNGFQKTSMRKIAILA
                     NMGKSSLYDFFKTKDEIFVYAVEKEIEETIKKVHRIIADESSPEQCLRKIMLNHLGVP
                     KQYRTVLMWLNTESDYLEEDYRKRLKTARYAYQDIIKSVIENGMESGVFRKTNANLMT
                     RLLINSIISIIYTSRPSASPEKMLDETMDIFLHGIMNDGGELL"
     gene            9819..12386
                     /locus_tag="PC494_001257"
     CDS             9819..12386
                     /locus_tag="PC494_001257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002602373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate, phosphate dikinase"
                     /protein_id="HDF3911765.1"
                     /translation="MIYYTLPLLHKQATLEMVGGKGMSLSKLLTTGIPVPEGFHVTTT
                     SYKIFVEKNHIQPYINKLLDGIDTNNTSQLENVSTQIGMLFHNGEMPQEVSDAIKTAY
                     ARLGNIAVAVRSSATAEDLPDASFAGQQETYLNIQGENEVLDAVKRCWASLWTARAIA
                     YRVKNDIKQEIVALAVVVQKLAFSDASGVMFTLNPINGRRSEMIVNAAWGLGESVVSS
                     LVTPDTIVVDKNAERIVSYEVANKEIMTVRNSDGTEEIPTPEQLRKKHALTRNQVMRL
                     TQLGKKIEKYYEMPMDVEWALEKDKLYIVQARPITVLPPEWTLPEKDVIYTRGSLAEH
                     LPNPVTPLFATLGLEIVNRASALLWIDMFGKSAKKLLPENGAYTIINGYVYLSANSKP
                     LLIAVKSLSPRSLRRALTNSVARWETARKEFEDVIKQWEEKPMHMLNAHQIMEGIQTV
                     FYGACIYFTRIQLTLPAASISETLFTKFFQGAARRAGMTDTSVFLLGFDTIALQAEKN
                     LWSLSEWVKQNNTLNLYLQSNPTAKIAENFMSSVPPDEVSLEVWIEWKNRINQYFKEF
                     GRTAYEFDFAYSTPQETLTPTFESIKTFVEGKGESPFLRQSKFEKHRKQAEEEILQHI
                     GSSRKKLFLKLLHWAQETAPMRENAIYCMGMGHPLIRQMFHEISARLIRGGATSHIDD
                     IYWLTKLELEKLIVQLDKNIPLSDRRNSILARKAELKKYQGYMPPAQLPEKKVKSISH
                     APQKQKDGKTVLRGIGTSSGVVTARACVLNSPADFKNFQPGSVLVAVTTTPAWTPLFA
                     SASGIVTDIGGPLSHSSIVARECGIPAVMATHTATRSIKNGQMITVDGSEGTVTIDE"
     gene            12379..13539
                     /locus_tag="PC494_001258"
     CDS             12379..13539
                     /locus_tag="PC494_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDF3911766.1"
                     /translation="MNKKPIFALNLATLVIALGYSLILPVMPFYMENLGAGGRELGWL
                     TAVYALAQTVCAPFWGALSDRIGRKPIISIGIIGYSISLFLFGLASSFWTLFIARSLS
                     GILSSATSVASLAYVGDSSSEEERSKNMSQLGASMSVGVMMGPLLGGILAGYSLALPF
                     FTGAGISFIAFLLILTLLPESIERSGQTEKRKPFDFSDLKSIIFGSAGMVLILIFVVH
                     FCQTGLQGITGLYVVDKFGFSTKQVGVIWMVLAGILIVVQGFLTGPLAKKIGEKRLIL
                     IGMFCKALVAFAMVLTTGFVSVLVVFGLFAVSSAITVPTLNATLSKTDNQHKGTLMGF
                     ASTAGNLSKVIAPLLTGYLYESNIELPYITTGGIALIGVVICYIWIKNQKNK"
     gene            complement(13726..13919)
                     /locus_tag="PC494_001259"
                     /pseudo
     CDS             complement(13726..13919)
                     /locus_tag="PC494_001259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227347.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
     gene            14022..14528
                     /locus_tag="PC494_001260"
     CDS             14022..14528
                     /locus_tag="PC494_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HDF3911767.1"
                     /translation="MKNEKKITVALLIVYLLILSWIILFKLQFSFSVLDHIRQINLIP
                     FGGSVIANGKIDFDEIINNAIVFIPVGAYFSLLFKNKSVLKAIGSVLGISFVYEIIQF
                     IFAIGASDITDLISNTLGGIIGIALVYVLSIVLKDKTHKILNRIAIVCTVLVVAFLFM
                     LLAVNNIF"
     gene            14533..14808
                     /locus_tag="PC494_001261"
     CDS             14533..14808
                     /locus_tag="PC494_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4865 family protein"
                     /protein_id="HDF3911768.1"
                     /translation="MLITCCFGKDFNLSKFAFEIEHEITPMEQMKAINFSLEKDDCTS
                     KVLIYNPDKWKYVEYYFYKDRPIKKLLEKFIQFCICHNKICFEILNT"
     gene            15078..15650
                     /locus_tag="PC494_001262"
     CDS             15078..15650
                     /locus_tag="PC494_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HDF3911769.1"
                     /translation="MNVDTIRTDIPTSSAVTDVIVWNIEQSGTDTLSATYEVDQQIKE
                     REQTTAVKATYTVKVHVDADGDMVIVQNLTLAPAIEKSDYEPKTSETDASVDADTVND
                     ATAFLETFFEVYPTATEKELAYYVSENVIEPIGRDYLYSELVNPVFTKDGDNVKVKVA
                     VKFLDNQTKATQVSQYDLVLHKDSNWKILG"
     gene            15753..16568
                     /locus_tag="PC494_001263"
     CDS             15753..16568
                     /locus_tag="PC494_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="effector binding domain-containing protein"
                     /protein_id="HDF3911770.1"
                     /translation="MFKIGEFSKLTQVSTRMLRYYDETGLLKPAKIDSLTGYRMYSAE
                     QISTLNRIIYLRDSGFNVAEIALALNFSNNAIIEQLDRKSIEIMDNIQKEQEKLKKIE
                     IAKKEVLHGKSELYFNITIKEIPSYCVLSLRKEIPNYYYEGELWKELSVFAKENKINI
                     SDETFSIYHNEEYKEKDVDVELCAIVNKIGKATGDFKFRFTEPVSMMACTMVYGDFFN
                     ISYAYRSFAKWLQENSQYKMKGSSRQIVHRGPWNEKNPENYLTEIQIPLENLL"
     gene            16649..17125
                     /locus_tag="PC494_001264"
     CDS             16649..17125
                     /locus_tag="PC494_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase"
                     /protein_id="HDF3911771.1"
                     /translation="MITYKVNSIGTIYNNEKGAFIQLEAAYIPALRALDGFSHINVLW
                     WFSDFDNTDFRSVLETEQPYKNAPEKMGIFATRSPVRPNPIALSVVEIINIDYMNGMI
                     QIAYIDANDKTPILDIKPYTPSLDRVENPNVPDWCSHWPHSLEESASFAWENEFNF"
     gene            17139..17690
                     /locus_tag="PC494_001265"
     CDS             17139..17690
                     /locus_tag="PC494_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDF3911772.1"
                     /translation="MSLQDYIIEKPVIDTEHLILRTMDKNDIDDLKEWISDISLYEYW
                     GKRPSKSEKNPEVLFSKPEKATKSFHWGIVHKQDSKVIGEIWIYLIENNRMAKVAFRL
                     SKQYQGNGLMSEALKSVIEFCFSKTELQKIWTDVHILNHASYKTLEKVGFQREGHIRG
                     GKMVNTYCDYYLYGILKSDYITS"
     gene            complement(18080..19249)
                     /locus_tag="PC494_001266"
     CDS             complement(18080..19249)
                     /locus_tag="PC494_001266"
                     /inference="COORDINATES: protein motif:HMM:NF033542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HDF3911773.1"
                     /translation="MFYIGIDVGKFNHCACVISSEGEVLIEPFFFTNNLDGFDSFIKA
                     VKKFKSPRHIVGLEATGHYGDNLINFLITHDYEVALINPLTTDAKRKSKIRKTKNDKK
                     DTFLICSVLFDRDYTRVTQRKLDMKQARELTRYHASIAEDINQKKNQLQKCIDIVIPE
                     FNTWFKTKYSKAYMAVLKEFGSSYNLASANLAHLKKVLKPKSSGSRVNIDASSLRSSA
                     KKSIGENNEAVTLEIKMLIENIELLASQLKTVDKKIEELAVKLDSPIFSIPGIGIYTG
                     MSILSEIGDIHNFSSAVKVMGFAGVDPGTYQSGEYSAPRTALSKRGSRYLRKSLYQCI
                     LTVCKYNLTFNKYYKLKRLQGKSHRCAQGHSVRKLIRVIYKLLSENIQFDEKLLI"
     gene            19528..20439
                     /locus_tag="PC494_001267"
     CDS             19528..20439
                     /locus_tag="PC494_001267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HDF3911774.1"
                     /translation="MYAYENIEMSLNYIEQHLSEKIETEKLAEIACLSTFYYQRLFKK
                     LVKKSVQEYIKLRRLAMVIAELNNSEERILDIALKYGFSDHANFTRAFKEVYHITPDE
                     YRKNVPMLNTFDKPELSSRYIMIDENVPLIVGNIVLEIQRKTLRTKETYFGFEKTVNI
                     AEQIPAGESTGIDVPGQLWREFHAKKLQTENAIFNNDIELGVSHLASPDKGTFLYFAG
                     GMVSSTDVCPKNMVQHTLPAGEYIVCKIEAESFEELVTTALNQANKYLFETWLPNHNL
                     VTKPFMAEKYYKGNAEINYMEVWIIPV"
     gene            20517..20951
                     /locus_tag="PC494_001268"
     CDS             20517..20951
                     /locus_tag="PC494_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3788 domain-containing protein"
                     /protein_id="HDF3911775.1"
                     /translation="MINIKDINYVPNISEISVYIENSAFDELYQHMNNEYKAVCKIEY
                     SKDVWARGWNVKFKKSGKSLCVVYPKKNYFTVLVVVGNKEKEDVENLLPRLSEYVQEI
                     YRNTREGNGQRWLMIDLKSKNNVYQDVLRLIEIRYAIKCVKP"
     gene            21419..22159
                     /locus_tag="PC494_001269"
                     /pseudo
     CDS             21419..22159
                     /locus_tag="PC494_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009243519.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
     gene            22110..22721
                     /locus_tag="PC494_001270"
                     /pseudo
     CDS             22110..22721
                     /locus_tag="PC494_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860758.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
     gene            22934..23791
                     /locus_tag="PC494_001271"
     CDS             22934..23791
                     /locus_tag="PC494_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002585362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDF3911776.1"
                     /translation="MYKEVGISSNNVPITLSIWYTERSSPTIVFLPGTMSHPLMYENF
                     LCGLSERGFNIIGIHYLSHGKSPKIKKNYTMEDLLHNVYDATTYGIENFGENIAVMGS
                     SQGGILAAMAAGRDTRLKAVFPHNIMLTTLKETMSLTKYPTWSHRFMGLIQWGFRVGG
                     KLLPNYKVPGDAYLDYDRVFYSEQAKQDCLNDPMLLPYYPLRFVASLFNADLSCLENG
                     AIQCPVILITAKGDPLFSFDYTNKVFDLIHVPQKELLALELNRHMIFNEDTDTTINAL
                     EATLHKYLG"
     gene            23869..24450
                     /locus_tag="PC494_001272"
     CDS             23869..24450
                     /locus_tag="PC494_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDF3911777.1"
                     /translation="MPRFTEQEKEIINSKLLIEGEKLFALHGLKKVTVDDLVAAVNIS
                     KGSFYAFYPSKEHLYVEINFRLQKELFTSIETTIKKKKYKNHRDLAKDVIMLSLTGVI
                     TSPILSQIDLSLMDYLQRKISSDIFENHMYSDIRILEILEDLGVVFLVPHTVIIKSLY
                     SVLSCLEQFKEDEELNMIQNLLVNGIIQQVVAE"
     gene            24554..25399
                     /locus_tag="PC494_001273"
     CDS             24554..25399
                     /locus_tag="PC494_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF3911778.1"
                     /translation="MIDVKKLYFSYTDKPFVENVSFHVGRGEIFGFLGPSGAGKSTIQ
                     KVLTGLNTRYKGSVKVAGTEIREHTNQFYENIGVDFEFSTCYEKFTARQNLAYFASLY
                     EKQPRSIDELLHMVGLENDGDKKVADFSKGMRSRLNFIKALVHDPDILFLDEPTSGLD
                     PTNSRLMKDIILAEKKRGKTIIITTHNMFDATELCDQVAFIVAGKVSALDSPHNLIMS
                     RGAAKIQYTYYDKGEKTGECLLDRTTEDKLLKSLISENRLLSIHSSEPTLNDIFVDIT
                     GRTLQ"
     gene            25396..26079
                     /locus_tag="PC494_001274"
     CDS             25396..26079
                     /locus_tag="PC494_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016295773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF3911779.1"
                     /translation="MRLGRLICGDIHFQWKYGFYFIYFILTVLYVCGIAALPEHWKTD
                     IASIMIYSDPAAMGLFFMGAIVLLEKSQKVLNAMVVSPVKVSEYILSKTIALIAISTV
                     IALILGVVSDSNHLLGITVGTALTSAIFTMLGIIAATKISNLNQFLIVIMPIEIVCFV
                     PPIVGLFVKLPYLFRFFPFTACMNLITGKSVLLSFDMVLVIATLIILYIVARHTVKHM
                     WKSLGGVKL"
     gene            26076..26774
                     /locus_tag="PC494_001275"
     CDS             26076..26774
                     /locus_tag="PC494_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002583502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF3911780.1"
                     /translation="MKRILSSTIQVFRQIKSDPMMFAACFTPFVMGALIKLGIPFLER
                     ITDFSLQAYYPIFDLLLSIMAPVLLCFAFAMITLEEIDDKVSRYFSITPLGKSGYLFT
                     RLGVPSIISAVIAFIVLLLFSLEKLSIGMTICLALLGSVQAIIVSLMIITLSSNKLEG
                     MAVTKLAALTLLGIPAPFFIDSYYQFAVGFLPSFWVAKAMQNEAVLYFSIGLVVALVW
                     YYFLTKRLFRKLAG"
     gene            26786..27697
                     /locus_tag="PC494_001276"
     CDS             26786..27697
                     /locus_tag="PC494_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HDF3911781.1"
                     /translation="MEKGRLLQNGKVNRAIQVSKITLFINLSLSLLKFTAGYIGKSSA
                     MLSDAVHSASDVLSTIVVMVGIKISEKQPDREHPYGHERMECAASIILSVALAITGAG
                     IGYSGIKKIFSEQYNTLSTPSGIALTAAVLSIVIKEWMYWFTRNAAKHTNSDALMADA
                     WHHRSDALSSVGSLIGILGARLGYAILDPIASVVICGCILKAALDIFKESINKMVDHS
                     CDNATETKIREVVLQQQGVDGIDELKTRMFGAKMYVDIEILADGNLALYDAHRIAEGV
                     HQTIENNFPQCKHCMVHVNTNELLYSA"
     gene            27749..27889
                     /locus_tag="PC494_001277"
     CDS             27749..27889
                     /locus_tag="PC494_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016295776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3911782.1"
                     /translation="MEQYWWIIIVVVLIVVGLLKIVIMKKYNQRRNSNNSPKDSEDDK
                     MY"
     gene            28179..28805
                     /locus_tag="PC494_001278"
     CDS             28179..28805
                     /locus_tag="PC494_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDF3911783.1"
                     /translation="MSDTKENILKIALHLFAVNGYEAVSVSMIAEALGMTKGALYKHY
                     KNKQDIFDCIVERMYQIDNKRAKDYQVPESTIEVTPNAYRNTTIGSLITFTLAQYDFW
                     VTDEFASNFRKMLILEQYRNLKVNMLYQKCLVNGPISYIEDIFNEMIEKGVLQECDTK
                     QLAIEYYAPLFLLISVADAVENCWDLKTQLTTHVKQFVKKYIINEKVK"
     gene            28927..29643
                     /locus_tag="PC494_001279"
     CDS             28927..29643
                     /locus_tag="PC494_001279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HDF3911784.1"
                     /translation="MEYIRSKKYFTPDLQTKIMGPNPIKLQEELLQNHKIPSGSYVCD
                     LGSGQGLTSVFLAKEYGFVVFAVDLWSEPKENEEFFKKMGLSSAQIKSVKADANELKF
                     EKEFFDAVVSTDSYNYFGRDPIYLDEKLLPFVKKGGFVYITVPGMKKDCHEKLPEELL
                     LSWTPEELDYIHDITYWSNIISHCKKADLISIYEMESNSEVWSDWIKQNNEYAINDRK
                     AIEAGGGDYLNFIAIILQKK"
     gene            29807..29998
                     /locus_tag="PC494_001280"
     CDS             29807..29998
                     /locus_tag="PC494_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003064779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4177 domain-containing protein"
                     /protein_id="HDF3911785.1"
                     /translation="MKKYEYVEINYNAKGVVFLCTDKHKEIIDSYAKTGYHYAGFVPT
                     EIDAKGCMRKIDLIFEKED"
     gene            30022..30252
                     /locus_tag="PC494_001281"
     CDS             30022..30252
                     /locus_tag="PC494_001281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3911786.1"
                     /translation="MIGLKRRNMNYIMKVGAKAQGVSVSEFRAMLQDTIDKTMESTDP
                     DVQANFKRYFGNKRPTPEEYIYTITKKTKVKV"
     gene            30519..30938
                     /locus_tag="PC494_001282"
     CDS             30519..30938
                     /locus_tag="PC494_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009261829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HDF3911787.1"
                     /translation="MKPSDFQKTIQCQFECKLKKVVKGIIWNYRKELKRRKNKEISFS
                     ELPDITVESLATWDDYETNYTIFNVCGIDIKVLDDELAEALKQLPEKKRNNVLMYYFL
                     EMSDTEIADIMNYTRGAVFKHRHRALETMKEILKEKK"
     gene            30941..31195
                     /locus_tag="PC494_001283"
     CDS             30941..31195
                     /locus_tag="PC494_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF3911788.1"
                     /translation="MKKKYKHPSYYLISSAMDGDETAIEKLLVFYDPYISKCCLRPLY
                     DEYGNVYIVVDMELKGRIREALIKMILDFEIDIDIETEEE"
     gene            31567..31770
                     /locus_tag="PC494_001284"
     CDS             31567..31770
                     /locus_tag="PC494_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HDF3911789.1"
                     /translation="MNNTDVPIWEKYTLSIEEASRYFRIGEKKLRRLAEENLDSGWVI
                     VNGNRIQIKRKQFEKIIDTLDEI"
     gene            31848..33038
                     /locus_tag="PC494_001285"
     CDS             31848..33038
                     /locus_tag="PC494_001285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006354938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HDF3911790.1"
                     /translation="MSKVKRQDSKGRNLRLGESQRKDGRYVYKYTDIFGKPQFVYAWK
                     LVPTDKTPAGKRDDISLREKEKQIKKDLDDGIDTVGGKMTVCQLYEKKNNQRKNIKRN
                     TKIGRQYLMNALENDPLGMRAIDTVKQSDAKEWAIRMNDKGYSYKTIDNYKRSLKASF
                     YMAIQDDCIRKNPFNFKLSDVLEDDTEAKVILTPEQEEKLLAFMETDNVYSKYRDEVI
                     LLLETGLRISELCGLTTHIDMLNRVININHQLLRDTEVGYYISTPKTKNGKRKLPLTE
                     RAYQALERILKNRGKAQPLVVDGYSNFLFLNREGLPKVAGNYESMVRGLIKKYNKTHK
                     DKLPNITPHSFRHTYCTNMANKGMNPNTLQYIMGHANITMTLGYYAHGTFQSAKAELE
                     RLAS"
     gene            33278..34099
                     /locus_tag="PC494_001286"
     CDS             33278..34099
                     /locus_tag="PC494_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MoxR family ATPase"
                     /protein_id="HDF3911791.1"
                     /translation="MIKKEISNFRGSSDYVVSPELMASVNVAIALEKPLLIKGEPGTG
                     KTMLAQAISNELKKDLVIWNIKSTTKAQEGLYVYDTVQRLYDSQFGGEGVDDISKYIK
                     YGKLGEAFSSNQQVILLIDEIDKADLEFPNDLLWELDKMEFYINETKETVRAKQRPIV
                     IITSNAEKELPDAFLRRCIFHYIEFPDRDMMEEIVKVHFDKVEEHLLEQVMTTFYWIR
                     SLKDIQKKPSTSELIDWIQALTLSGMPIEKIEKEVPFAGILLKNNEDIESMQRHL"
     gene            34120..35316
                     /locus_tag="PC494_001287"
     CDS             34120..35316
                     /locus_tag="PC494_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VWA domain-containing protein"
                     /protein_id="HDF3911792.1"
                     /translation="MFIEFFYLLRSRGLNVSLNEWMTLIEALDKGLCYSNFSNFYYLC
                     RMILIKSESDFDKFDAVFLEYFKGIEHQEEIPEEIMNWLKKPDIDLEEFERLEQNPNI
                     NLDKLRAKLEERIKEQDSPHNGGNYWIGTGGTSELGHSGKGQTGIRIGGNSTYGRAVL
                     EVAGERKYRDFRDDEVLNMRQFQVALKRLRQFSTRIDAPKTELDLDKTIEETCNNAGY
                     LKLFFEKPRKNTVKLLLLMDSGGSMRGYSTLCNTLFQSVSKSNHFKDVKIYYFHNCIY
                     DRLFTTPECWLSKSINTEWILKNIDKNYKVIIVGDASMSPSELLHIGGNYRGPYNYTP
                     GIEWLKRFKRKYSKIVWMNPELRDGWDSINYWYQTQRMIQSEFNMFPLTVKGLEKALK
                     NLMVSR"
     gene            35484..38882
                     /locus_tag="PC494_001288"
     CDS             35484..38882
                     /locus_tag="PC494_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HDF3911793.1"
                     /translation="MIIINYELIVKYNGDILRLEEELGVSVEILNSSYAIITSSNEED
                     VNILLTYPEIEFIEKPFILQTQDVQSFSSTGITGFKNRTGLTGKGTIIGIIDSGIDYT
                     LPVFRDSDGRSKILYYWDQSIQGNPPEGFREGTLYTNEDINNAIDGSMYIPISTTSLH
                     GTHVAGICATIASDARIIVVRVGNIQTDIFSRSTEFMRAIKFILDRALELRMPVTLNI
                     SYGSNEGSHRGTSLFEQYIDDMCLFWKNNIVVAAGNNADKGGHKRIRLQNNITEEVEF
                     IVGEGERILNINIWPDFVDDFSVHLVNPSNNQTQAISLTSGEIRNTLGETRITGYFYP
                     IAPYSLTRRVTLQLSSNTQITPGLWKIVFEPIDIVTGNVNIYLPTSEGLNRNTRFLIP
                     TQELTVTVPGTASRVITVGSFNSRTDIVSIFSGEGDTQLGVFKPDLLAPGEDIVSFLP
                     GGTSGALTGTSMATPHVTGVCSLFMEWGIVNGNDLFLYSQKLRALLLKGARRLSNQSY
                     PNNSSGFGFLNLSDIDLYTLSNINQDLETEDIGYRSINKSFKDEENSYKFIDGYNMQI
                     HNDLENEIYISKNASRQSGILSGIDIVHTPEFEEELAGLGMSQRFFKISDSLGVLSIN
                     NTDYNSIQRVLQLPSIIRTVSTTKMTLLGEINRGTFGGVVATEEMGVNFFKNNPNINI
                     TGRGTLISIADTGIDYLHPDFIYPDGTSKIVYLWDQTKEGTPPDGFYIGTEYTREDIN
                     RAIAENDPSLSQDEVGQGTMLSGICAGLGNVNSEYAGIAEDSELIIIKLGKIDDFYNS
                     AMLFAASQYAYKKAFELGRPLVINMSLGTSSLAGLTNRSNSEKAFFTRGLCITAGAGN
                     EGNTQTHTSGIIPYVGGSVEVELELNEDEEELSLELWLNRPDKADVIIVSPTGEESKS
                     VGISNYNKVTGLFDLEGTEYSITYIYPTTFSGQQFTNVTLKNAKRGVWKIRLVGVYII
                     TGRYNLYLPNRELLKSGTRFREVDPFYTINYPAIQDDLITIGAYNTINGSLWQSSSRG
                     PTIEDRLKPDIVAPGVNIIAAYPGNTYATITGTAAASAHAAGAAAMYFQYTFVDGRYP
                     NQAYVQKIKTFMQAGARKDSNTVYPNTNSGYGLLDVRGMFDVLR"
     gene            38892..40565
                     /locus_tag="PC494_001289"
     CDS             38892..40565
                     /locus_tag="PC494_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family peptidase"
                     /protein_id="HDF3911794.1"
                     /translation="MEKSYCIIYQGDIESALQENGINRYMVLNSQLAVIYVPLDFDET
                     ILNNIIQVAWWEESEPMSSLIEITNNVNNGETITTAAETDYIYENPYNDITGRGILLA
                     VIDSGIDYLHPDFINDDGTSKVLYLWDQEANTNPPPEGFIFGSEFTRSELNIAINRND
                     GSLSQDNIGTGTLVSGILVGNGRINSQYRGITTESDLIVVKLKSYTDTYYAGRINYSV
                     SDFLAAITYVTNIARTENKPLIINLTIGVKSSAVATTSILDTFNILSSAGVVVVSGAG
                     NQGNTDIHYSGRFSSVGEVQDVIIQDGDDYALDITLNTNGPDKVGAQIISPSGEVSHD
                     IRYSPDFYIYRGKFNLENTTYAMRFIYPYITSGKENLEIRLRDIKPGVWILRLTSELI
                     INGEYDIYLPNKNLIAPDTRFLDPDSVATITMYAASDDVITVGTFNNKTDSMWIGSSK
                     GPIRGRGIKPDIVASGVDIISTYKNGTYNTGTGTGVSSSIVTGVLALLMEYLEKQDNV
                     PRLSLFTQVLKTYLILGATKLEIYTYPNVSQGYGILNLKNTIQQIANTL"
     gene            40838..41032
                     /locus_tag="PC494_001290"
     CDS             40838..41032
                     /locus_tag="PC494_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3787 domain-containing protein"
                     /protein_id="HDF3911795.1"
                     /translation="MESKKARALKGKDNKRLKSSLLVGNESTAAWADVEKLKPHSKVS
                     IPSIKGVEEAKDWVDNGSKL"
     misc_binding    41201..41434
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            41511..42908
                     /gene="asnS"
                     /locus_tag="PC494_001291"
     CDS             41511..42908
                     /gene="asnS"
                     /locus_tag="PC494_001291"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HDF3911796.1"
                     /translation="MQKEFITVKELYREKEQYIGKTVKVAGWIRTSRVSKNFGFIELN
                     DGSFFKNMQIVFDEKVENFKEVGKLAISSSILVEGELVSTEGAKQPVEIHAKSIVVEG
                     ESDSSYPLQKKRHTLEYLRTIAHLRPRSNTFSAVFRVRSIAAYAIHKFFQERNFVYAH
                     SPIITGSDCEGAGEMFRITTMDLNDIPKTEDGKIDYTQDFFGKEANLTVSGQLNAEIM
                     ALSFRNVYTFGPTFRAENSYTGRHASEFWMIEPEIVFADLEDNMELAEDMIKYVISYV
                     LENAPEEMEFFNSFIDKGLLERLNKIVNSEFIRITYTKAVELLIESGHEFEYPVEWGC
                     DLQTEHERYITEQIYNCPVFVTDYPKDIKAFYMRMNEDGKTVRAMDLLVPGVGEIVGG
                     SQREEREDVLLDRINEMGLREEDYWWYLELRKFGTATHSGFGLGFERIIMYMTGMSNI
                     RDVIPFPRTPKNAEF"
     gene            complement(43081..44256)
                     /locus_tag="PC494_001292"
     CDS             complement(43081..44256)
                     /locus_tag="PC494_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HDF3911797.1"
                     /translation="MNLEKIKKFFGFPLDKKHKDNVEKELCNYLYHTGKIICIIIVIS
                     QIIMMISISAREGGPFVTPRRQWYFYMYVTLFCVSSVFMFVFSYLWNKKKDCCTFYIN
                     LWIIYVTFFCLWGCVITLLDQLGGNDLSVFSYIMLAAAAFSVLKFGESVIVFGGCFLF
                     LNLFLPGIQTIPGNEFSNIVNTFFITSLAIFVSTMLYRNRVFTYYDKLLISQQYEEIS
                     HINNLLNDKVMTDDLTKMNNRRYLEDILQKKLISHANQEPITGMMIDIDYFKQFNDNY
                     GHQKGDYCLQNIAKVILDFTSSENEHAIRYGGEEFFICIFNCNEADAKLKSECLRKII
                     ESCNFERDDVPLKCVTVSIGVYTKKIGKTITLNEFISNCDKALYTAKEQGRNCVAFY"
     gene            44675..46039
                     /locus_tag="PC494_001293"
     CDS             44675..46039
                     /locus_tag="PC494_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HDF3911798.1"
                     /translation="MGEKKINNMNYSHNNYSKKTGEPTRKIKNSHITLKSKEEKICSS
                     CNKENNTKDNYCKFCGNELYEIASLRPLETKLDLKSKIKELSYHANKRGVFLTTFTTI
                     FILFIIALIFKAIITIQFNDISYLVNPAHIILALNLGQISVSMSTMMGSGFINANIGL
                     LILLIIPILVLLISNLIFMRKRCRDSKTVLANSLGVGIFYGLVLAILSIFTNVKTSSH
                     SMLEYGYALEYSYEFFSVLLNGFVLGFICTYITTYKKSYEKENMYLSLFSNSIRTFIL
                     GYVLVLVILLVLTISDSSYLNELDMSSYSNGLNLFTILPQIASYMWAFANGISVTIIN
                     STVSMFTLSSSSLFGDTKLMFYAMGALSMLILLLNGYKLRFKYNTDSIRPIIVFSIYY
                     AFLMGILALFSTFILDSNINFFNTTNYGTTLIMQFKVLQAIVISFVYSFVISLIGYKL
                     NSAD"
     gene            46061..46552
                     /locus_tag="PC494_001294"
     CDS             46061..46552
                     /locus_tag="PC494_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HDF3911799.1"
                     /translation="MEGNTNNKVDDKFSKVKKKFGSGKFKVELYKEKSKLNREIDDIQ
                     EEKAKIFLEMGILTYQKIREDSINDNSFDKLCDELLELDKLIYEKNMEINEMEMAESN
                     VTCECGYVGNVNDKYCAECGKKFELENECDDFIICGYCESEIDTEAEFCPCCGRKIII
                     DLE"
     gene            46825..47496
                     /locus_tag="PC494_001295"
     CDS             46825..47496
                     /locus_tag="PC494_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HDF3911800.1"
                     /translation="MLDKVKGRLIVSCQALEDEPLHSPFIMGRMAKAAMEGGAVGIRA
                     QGVEDIIEIKKVTGLPVIGIIKRNYEDSDIYITPTKKEVDELLTTGCEMIALDATNRV
                     RPNNEDLKELIKYIKENGVLVMADISNYDEAIKAQEYGVDCVSTTLSGYTPYTKTLEG
                     PDFVLMERLVKDLEIPVIAEGKVNTPQDLKKVFELGVHSSVVGSAITRPQLITEKFVK
                     AIEIN"
     gene            47581..48447
                     /locus_tag="PC494_001296"
     CDS             47581..48447
                     /locus_tag="PC494_001296"
                     /EC_number="4.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003452648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylneuraminate lyase"
                     /protein_id="HDF3911801.1"
                     /translation="MKGIYSALLVSFDKEGNINEKGLRQIIRHNIDVCKVDGLYVGGS
                     TGENFMLSTDEKKRIFEIAKDEVKEEIKLIAQVGSVNLKEAVELAKFTTDLGYDAISA
                     VTPFYYKFDFEEIKHYYNTIINSVDNRLIIYSIPFLTGVDMSLDQFGELFENEKIIGV
                     KFTAADFYLLERMRKTFPNKLIFAGFDEMMLPATVLGVDGAIGSTFNVNGVRARQIFE
                     LTKNEKISEALEVQHVTNDLITDILGNGLYQTIKLLLEEQGVEAGYCRQPMKEATDEM
                     KSRAKEIYRKYF"
     gene            48480..49982
                     /locus_tag="PC494_001297"
     CDS             48480..49982
                     /locus_tag="PC494_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003462875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:solute symporter"
                     /protein_id="HDF3911802.1"
                     /translation="MVGFTWIDFAILVVYLLAVLFAGLLFSKKEMKGKEFFKGDGTIP
                     WWVTSVSIFATLLSPISFLSLAGNSYGGTWILWFAQLGMFIAIPLTIKFFLPLYSRLE
                     IDTAYEYLEMRYESKGLRVLGALMFIIYQIGRMSIIMYLPSIVLAGLTGIPVNVLIIV
                     MGVIAIIYSYTGGLKAVLWTDFIQGMVLIVGVTGTLFYLIASINGGFGTVMDTLTTGH
                     KFLASNEVMFDKNILSTSAFIIFVGAGLNTFSSYVSSQDIVQRFTTTTDIKQLNKMTY
                     GNGVLSMGLATVFYLIGTCLFIYYTQNPDLAQTVQQDQVFASYIAYELPVGITGILLA
                     AIYAASQSTLSTGLNSVATSWTLDIQTIITKDISMEKQTKIAQYISLGVGILSIAVAI
                     VLANGEIKSAYEWFNSFMGLVLGVLAGIFVLGAFCKKATKMGAYVGFIVSAILVVYLK
                     YRMPEVTSWAYSLITITTSVVVGTIVSAIEAKVKAKVSLPKAETTVYYEK"
     gene            50112..50564
                     /locus_tag="PC494_001298"
     CDS             50112..50564
                     /locus_tag="PC494_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HDF3911803.1"
                     /translation="MIFGNINHSKTYSTLHEDLLRCFEYAKDNSLIDYEKGTYTIDGD
                     DIFVNIVEYKTCEKEDRFWEAHKKYIDVHLMLDGCERIDINFIENLEQKIYEEKGDFL
                     PLDGKNNGYMELRKGDFLVCYPEDAHMTGIKVLEKENIKKAIFKVLVR"
     gene            50724..51527
                     /locus_tag="PC494_001299"
     CDS             50724..51527
                     /locus_tag="PC494_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3911804.1"
                     /translation="MENIDVFLLIGQSNARGLGNPKESIIPNENCFEYLSTDEIINMR
                     CELETSEGDGTIAPAFSNEWNKLTGNKVCFIHNAKDGSRIKNWNHDNNWFLNDTIEKF
                     NTGCTTLSKHYNIENKYVIWIQGESDAKYGSDVLYYKESLKKIAYRLKEECMIDKMFV
                     SLTGYWLGEDEYFIRTRRIAAAQESACSECDILCVGSKIAMQFHDRGLTIDDVHYTQE
                     GLNMLGEDLCKNIYKYHITKEKSVLSDTIDLSEARKYICELEKISKRFV"
     gene            51585..52472
                     /locus_tag="PC494_001300"
     CDS             51585..52472
                     /locus_tag="PC494_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HDF3911805.1"
                     /translation="MKNYVCIDVGGTSIKYGFIREDGFIIDKSSLDTEAKEKGGEGIL
                     AKIKDIVKKYIEENEISGICISTAGMVDPVEGKILFALEELIPNYKGMQLKKEVEKEF
                     NIKCEVENDVNCAGLGEMWLGAGRGATSSICLTIGTGIGGCIIINNKLINGFSNSAGE
                     VGYMNVNGSSFQELASTSSLIKKVAKIKNLNENDLNGKIIFDLAKNNDEDCLKELDNM
                     IKSLAVGIANICYVINPEVVILGGGIMAQEKFLKPKIDKALKEVLIERVYKNTNIEFA
                     KRQNDAGMLGALYNFLNKI"
     gene            52491..53339
                     /locus_tag="PC494_001301"
     CDS             52491..53339
                     /locus_tag="PC494_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HDF3911806.1"
                     /translation="MSILEQLESPTFKVTKSDKLLIAYIKENIDDVFYKPISQIAKES
                     NIGEATITRFVKKMNFNGLQDFKVTLAQEISTINKKNIINKNIQNDEPALDTAKKLLS
                     SNVTTLENTVEIINSKDVHDCARLIINAKKVYFIGIGYSGIIAQDSNYKFMRIGLNCV
                     SFDSSHTMIMMSSIMEEGDLIIAISHSGETEEIIKTVKLARANNAKIISITENKNSEL
                     KDISDVHLSYVSGETVLETGSISSKLAQFFIIDLVYTQVVKELSNEAIERKIKTTNAI
                     KLFKNE"
     gene            53402..54091
                     /locus_tag="PC494_001302"
     CDS             53402..54091
                     /locus_tag="PC494_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HDF3911807.1"
                     /translation="MSKLKDYNIDKVIIFNNLSTKTKNQLKEKVKLKRLQKKEILFYE
                     KDSLDSVYILLEGKVSIFKISENGERKVIFILNSGEVINDITLDASKNSTVGCEAFEN
                     SIVAYYSIEEFLEIMQNDFQLTKDIISYMERRIRRLYRQLKNSISIKVDKKLAAKLYR
                     LSREFGVCCGEWTLLNVNITVTYLADMLGCKRETVSRMIKVLQKEELIKIDNKGFYVK
                     ETELSRYFKNN"
BASE COUNT        19186 a         7819 c        10771 g        16320 t
ORIGIN      
        1 acttggtttt taagcaacgc acagagttta gtgcttatgg cgattgtggt aattggtatc
       61 tacttaggtt ttaagcgtga gttttcaaaa cttatcggct tcttggtagt tgctcttgtt
      121 gccgttggct tggtattcaa cgctggtggt gtgaaagacg tattgttaga actgttcaat
      181 aagattatcg gtgcataaaa ttttattgta gtgtgagtgt agaaatggta tgatatggat
      241 atgaagaaag caacaaatta gaagttggag gaacaataat ggactacaaa gtagatgata
      301 aaaaccttga tgcatcaatg tttatttctt ttgtcaatca agtatggcag ggcgattatg
      361 atatggaaca aacaaggcaa gcattatcta aaacactaaa cataacagcc tatgacaata
      421 aaaagttagt agggtgtttg cgtattcttt ccgatggtta ctattttgga acaattacag
      481 agctacttgt tcttcctcaa tatcaaaaac agggtattgg aagtaaactt cttcaacttg
      541 caaaagacaa tacacctaca atgttatatt tcggttctca accagaagca gagaagtttt
      601 atgaaaagaa cggctgtcaa aaaagcttac aatcttacat gataaataag ggataataag
      661 agataacttc cagcttgaca attttatatc catatacaca aagcagttag tcttaggatt
      721 gactgctttt ttcttaccta aaaattagat tggagtgatg taatgaacga tatttttaag
      781 aatatgcagg caaaaatcgg ctgtgaatat ctttctgacc tgccctctta caaacgtaag
      841 gtgtggcatg aaatgaaaca actgaacctt gccgattatg aagagaaaca gttagaagat
      901 ttttcaaagt atgtgtttgg tatgtcatac cagaccttaa aagatgtgat gaaacaacag
      961 ataggacgtg aggaacaatg caggaaacaa gggtactggt ggaaacgaaa agaacaactg
     1021 acgaagaaac aacatcatac tggttcgacc tgccgataga ggttgccgaa tttgaggaaa
     1081 aattaggtgt cggtgcagaa agtggggaat accgtattat cgaaaaggta ttgccttatg
     1141 ctgatgaagt ccacgaacat acaagcgtgt accagctcaa caaattagat tttatgtacc
     1201 gccagctttc aagcgatatg caggaagaat atgtatcact acttatggtg tttgagaatt
     1261 tagaagcact ttatatttgc agaaatgtaa ttaccgttta tcccgactgt aaaagtatga
     1321 tagatgttgc aaggcaaaag ctgatgaacg acccgacgtt caaacattta tctgaggact
     1381 gtcaagaata ctatttcaat tttgaagcct acgcttctca cttgcaggaa cacgggaaat
     1441 ttttagtaac agaacacggt atctttgaac tgccagagta ggaagtgagg tggggcttat
     1501 gattgatgat atggcggttt atattgctaa tcttggcaaa tacaatgagg gatatttagt
     1561 cggtgcgtgg ttctctttcc ctattgacga ggaagatgtg aaagaaaaaa tcggtttgaa
     1621 tgaacaatat gaggaatacg ctgtccatga tactgacaac ttccctatcg acatagggga
     1681 atatgtttcc attgaagaac tcaatgagat gtatgaaatg atagaggaac ttcccgacta
     1741 tatcgtagag tgtctggacg aatttatcag ccactacggg acgctggaag aagtcgtgga
     1801 acacaaggac gatatttatt attatccaga ctgtgaaacc atgacagacg ttgcctacta
     1861 ctacatagac gaattgcagg cacttggcga cattccaccc agcttacaga actacattga
     1921 ctatgaagcc tacggtcgag atttggatat gggcggttgc tttattgaaa caagccgagg
     1981 tatgtgcgag ataccttatt aacgctggaa gatcagcgac aagcattgtt gctactgaca
     2041 gcgtatttct cttttaaggg acagtctgaa acatggctgt ccttttctct ttttaagaac
     2101 ttacgaaagg agctgaaaga acttgaaaaa gattaaaagc tacacgggta tctggaacgt
     2161 ggaaaaagtc ttgtatgcaa tcaatgactt taacttaccc tttcccgtta cctttacaca
     2221 gattacatgg tttgtaatta cagaatttat catcattctg tttggggata tgcccccact
     2281 ttccatgatt gagggagcat ttctcaaata ctttggtatt cccgttgctc tcacttggtt
     2341 tatgtcgcag aaaacctttg acggaaagaa gccgtacagc tttttgaaat cacagataac
     2401 ctatgccctg cgacctaaaa tcacttatgc aggaaaagcc gtaaaactgc ataagcagac
     2461 cttgaatgaa acaatcacgg cagtaaggag tgtgaactat gttcccgata aaatatattg
     2521 acaataacct tgtctggaac aaggacaatg aggtgttcgc ctactatgag ctgataccat
     2581 acaattattc tttcctatcc gcagagcaga aatttatcgt gcatgacagc tttcgacagc
     2641 taatcgcaca gtcccgtgag ggtaaaattc atgcgttgca gattgccaca gaaagctcaa
     2701 tacgaagtat gcaggagcag tcaaagaaac tggtaacggg gaaacttcgt gaggtggcag
     2761 tccaaaaaat agacgaacag accgaagcgt tagtatctat gattggggac aatcaagtgg
     2821 actaccgctt ttttcttggc tttaagctca tggttacgga agaacaactc aatctgaaga
     2881 atattaaaaa atcggcatgg ctgacgttca cggaatttct ccatgaagtg aaccacacgc
     2941 tgatgaatga ttttgtttcc atgccgaatg atgaaatcaa ccgttacatg aaaatggaaa
     3001 agttactgga aaataaaatc tcccgtcgct ttaaggtgcg tcgcttggaa atcaatgatt
     3061 ttgggtatct catggaacat ctttacggca gggacggtat cgcctatgaa gattatgagt
     3121 accagctacc agagaagaaa ttgcagaaag aaacgctgat aaaatactac gaccttatcc
     3181 gcccgacaag gtgtgtgatt gaggaaagcc agcggtattt acgattggaa catgaggaca
     3241 aggaaagcta tgtgtcttac tttactgtca atgcgattgt aggcgagctt gattttccgt
     3301 cgtctgaaat cttctatttc cagcaacagc agtttacatt ccccgttgat acttctatga
     3361 atgtagaaat cgtggagaac agaaaggctc ttagcacagt aagaaataag aaaaaggaat
     3421 tgaaagacct tgacaatcac gcttatcaag caggaagtga aaccagctca aatgtggtag
     3481 acgctttaga cagcgtggac gagctggaaa cagacttaga ccagagcaaa gaaagtatgt
     3541 ataagttaag ctacgtgata cgggtgtctg cacccgatct tgacgagctg aaacgccgtt
     3601 gtgatgaagt caaggacttt tacgacgacc tcaacgtaaa gctggtgcgt cctgctgggg
     3661 atatgctggg gcttcattct gaatttttac ctgccagcaa gcgatatatc aatgactatg
     3721 tgcagtatgt aaaatcagac ttcttggcag ggcttgggtt tggtgctacc cagcagttag
     3781 gggaaaatac gggtatctat atgggctatt ccgttgatac gggaagaaat gtgtacctgc
     3841 aaccgtccct tgccagtcaa ggtgtaaaag gtacagttac caacgccctt gcgtctgctt
     3901 ttgtcggttc gcttggcggt ggaaagtcgt tctgcaacaa tcttcttgtg tattattcgg
     3961 ttctctttgg gggacaagcg gttatcttag acccaaaatc agagcgtggc aactggaaag
     4021 aaacacttcc agaaatcgca catgaaatca atatcgtaaa tcttaccagc gacaaggaca
     4081 atgcaggact tcttgaccca ttcgtgatta tgaagaatgt aaaagacgct gaaagtctgg
     4141 caatcgatat cttaacattc cttactggta tttcctctag ggacggcgaa aaattccccg
     4201 tacttcgtaa agcggtacgc tccgttaccc agagcgacag tcggggcttg ctccatgtga
     4261 tagacgagct acgccgtgaa gatacgccca tatcaagaaa tatcgcagac catatcgaca
     4321 gcttcacgga ctacgacttt gcacacctgc tgttttcaga cggtacggta gaaaatgcta
     4381 tcagtctgga taaccagctc aatatcattc aagtagccga ccttgtgttg ccagataagg
     4441 acacgacctt tgaggaatac acgaccattg aattgttgtc tgtgtctatg ctgattgtga
     4501 ttagtacctt tgcccttgat tttatccatt cggacagaag catttttaag attgtagatt
     4561 tggacgaagc atgggcgttc ttaaatgtgg cacaaggcga aaccttatca aataagctgg
     4621 ttcgtgctgg acgagctatg caggcaggcg tctattttgt tacccagtct gcctatgatg
     4681 tttcaaagga aagtctgaaa aataatatcg gcttgaaatt tgcctttaga agtaccgata
     4741 taaacgagat taaacagacc ttagaatttt tcggtatcga caaagaggac gaaaacaacc
     4801 agaaaaggct tcgtgatttg gagaacggac aatgcttgtt gcaggactta tacgggcgtg
     4861 tcggcgtagt acagatacac ccagtctttg aagaactgct acacgccttt gataccagac
     4921 cgcccgtaca gagaaatgag gtggagtgat gaaagaaagg atacagagtg cgttcacaaa
     4981 aaagaagatg ttccgctttc tcaagataac ggtgtttgtc gtggcacttt cccttatcct
     5041 gctttcacta cttgaaacgg tggctcatgc aacggggctt gtggacgata cgataaatac
     5101 agaaaattta tattctaaat atccgttatc caactatcag cttgattttt atgtggataa
     5161 tagctgggct tggttgccgt ggaactggct ggacggtatc ggaaaatcgg tacagtacgg
     5221 gctttactgt attactaact tcgtttggac tatcagttta tatttaagca atgccacggg
     5281 ctatgtggtg caggaagcct ataagctgga cttcatcaat gatatggcag acagtatcgg
     5341 acagagcata cagacccttg caggcgttac ctcaagcggt ttttcaacct ctggcttcta
     5401 tgtcggtttc ctgcttctca ttatcttggt ggtgggaatt tatgtagcat atacgggact
     5461 gattaaaaga gaaaccagca aggcacttca cgccgttatc aactttgttg tggtgtttat
     5521 tttgtcggct tcatttattg cctatgctcc cgactacatc aaaaagataa atgaattttc
     5581 aagcgacatc agtaccgctt ctttggactt gggaacaaaa atcatgctcc caaactctga
     5641 cagcgagggc aaggacagcg tggacttgat aagggacagc ctattctcta ttcaagtgga
     5701 acagccgtgg ctactcttac aatttgggaa cagcaacgca gaggaaatcg ggacagaccg
     5761 tgtggaagct ctggtatcgg taagcccaga ggacgaggac ggaaaaacca gagaggaaat
     5821 cgtgaaaaca gaaatcgagg ataacgacaa caacattctg acgataccgc aggtagtaaa
     5881 ccgtttaggt atggtgtttt tcctcttatt cttcaactta ggtatcacga tatttgtatt
     5941 cttgcttacg ggcatgatgt tgttcagcca gatacttttt attatctttg caatgttcct
     6001 gcctattagt ttcctgctct ctatgatacc gagctatgaa agcatggcaa agcaggcaat
     6061 cgtgagggta tttaatacca taatgacacg ggcaggaata acgctcattg taacggtggc
     6121 gttcagcatt tccagtatgt tttacaatat ctccacagac tacccgttct ttatggtggc
     6181 gttcttgcag atagtttgtt ttgcaggtat ctatatgaag ctgggcgatt taatgagtat
     6241 gttctcactt aatgccagcg acagtcaaag catgggacgc aggatattcc gcagaccgta
     6301 tctgtttata cgacatagag cgagaagaat ggagcgacgt atggcaaggg cggtaagtgc
     6361 tggcggtatt tcgggcggtg tcgctggtgc gctggctggc agtaccgttt ctaatgcaag
     6421 gacaacaaga aacaatccta caaaggaaaa tcggggcaat accacttcca tcatgggaca
     6481 gcgtgcaggc tcaaagatag gcgctgtctt agatacgaaa aataaagtga aagacaaggc
     6541 aaatgctgtc aaagagaatg ttaaggatat gccgacacag accgcttatg cggtgtattc
     6601 tgcaaaagaa aaggcaaagt ccagcgtgtc cgacttcaag cgtggcatgg tgcaggaaca
     6661 gcaatccaga cagacgggac gcttagaaaa gcaggaacaa cgtaaaaaaa atatcgctaa
     6721 caagcgtatg gagcttcaaa aggcacaaga agcaaggcag gcacgaaagg ctgacggatc
     6781 agcgacaacg ggagctaccc gtccccatga gcgaccagcc acagcttcaa agccgagtgt
     6841 ggaaaaagtg caggaagtca aacgccctgc cacaactccg acttcaaaag caagtgagcc
     6901 agtcaagaca aatgttatca aagagcgtcc gctatcttcg ggtgcttctg acggaaaagc
     6961 aacccagtcg gcacagccaa tacataggca gaatatagaa aaagtggtat cgcaggaaac
     7021 acgccagaat tacgttaaag accgcaggac aaaggttcag cagacgcaga gcgtccagaa
     7081 gaaccagcag accacagaga aaaaccataa ccttgtaacg aagaaaggac agaagaaaaa
     7141 atgaaactga aacatatcgc tcttatcggc agtctgtttc ctatcctctt ttccatagtc
     7201 cttttttttg gggtgctgat tagtgcggac agcgacgacg aaaacagcaa cttttcttct
     7261 ggtattacgg gtttgaacct atccgcagaa gtcttgaaac atcagcctat ggtggaaaag
     7321 tacgccagag aatacggcat ttccgagtat gttaatgtat tactggctat cattcaagta
     7381 gaaagtggcg gtacagcgga agatgtcatg cagtccagcg aaagtctggg actaccgccc
     7441 aactctttag atacggaaag ctcaatcaag caggggtgta aatattttgc gtccctgctt
     7501 tcttcctaca aaaatcaagg aataaatgac ttgaatgtgg cgatacagtc ctataactat
     7561 ggcggtggct atgtgggata tgtggcagga aaagggaaaa agcatacgtt tactcttgca
     7621 gagagcttcg cctgtgaaaa atcgggtgga aagaaagtaa cctacaccaa cacgatagcc
     7681 gttgcgaaga atgggggctg gcggtatggc tatggaaata tgttttatgt ggaattggtc
     7741 aatcaatatc tgactgtacc gcaggtatcg ggagaactgg cacaaaagat aatgaatgaa
     7801 gcgttgaagt atcaaggttg gaagtatgtc tatggtggca gtaatccgaa cacttccttt
     7861 gactgttcgg gacttgtgca atggtgttat ggaaaagcgg gtatctcttt accgagaacg
     7921 gcacaagccc agtatgacgc aacccagcat atccccttgt cgcaggcaaa ggctggcgat
     7981 ttggtgtttt tccattcaac ctataacgct ggttcgtatg taacccatgt cggtatctat
     8041 gtcgggaata atcagatgta ccatgcaggc gacccgatag gatatgcaga cctcaatagt
     8101 agctactggc aacagcactt aatcggtgca ggacgagtaa aataaaagaa aggacttaga
     8161 aaatatgttt aagaaaagta agaaacagac agaaaatgtc aaagaaaaaa aggtgcgtac
     8221 tgtcaaggta ggcacacata agaaaactgt aattgcgttt tgggtggtgc ttatcgtaag
     8281 tgtaagtttt ggggtatata agaattttac cgccattgat atgcacaccg tacatgaaac
     8341 agaaaccata caattaagac ttaccgatac taacgggatt gaaaatttcg tgaagaactt
     8401 tgcgaagtcc tattacacat ggaacaacag caaagaagcg attgaagcaa ggacgcaggc
     8461 aatcagcggt tatctgacaa aggaattgca ggacttgaat gttgatacca ttagaaccga
     8521 tataccgacc agttccacgg ttacagatgt gattgtttgg aatatcgaac agtcaggaac
     8581 ggacactttt tctgctacct acgaagtaga tcagcagata aaagagggag aacagacaac
     8641 agcagtcaag gcaatctata cggtaaaagt ccatgtggac gttgacgggg atatggtaat
     8701 catacagaac cctacgcttg caccaacaat cgaaaaatcg gactatgagc taaagacacc
     8761 agaagcagac gcaagtgtgg acgctgatac cataaatgac gctacttcat ttttggaaac
     8821 attctttaag ctgtacccaa tagcgacgga aaaagagctt gcctattatg tatcgggaaa
     8881 tgtgcttgaa cctatcggca aggactatct ttattctgaa ttgataaacc cagtctttac
     8941 aaaagacggg gacaatgtga aagtcaaagt tgccgtgaaa ttccttgata atcaaacaaa
     9001 ggcgacgcag gtatcgcagt atgaacttgt gctacataag gatagtaact ggaaaattgt
     9061 gaaataataa tttaaagcgt gcatttctta taagatttgt acgctttact tttatggtaa
     9121 aaattagcct tgacaagcga ccgttggtcg ctatataatg aaagcgaaac aagaaacgac
     9181 cgatggtcgc tataaggagg tatcataaat atgccaaaag gaattatgct tacacaagaa
     9241 caacaagaag aacgccgaga agaaataatc agtgttgctt tgcagctcat agagaaaaat
     9301 ggattccaaa aaacatcaat gaggaaaatt gcgattttag caaacatggg aaagtccagt
     9361 ctgtatgatt ttttcaaaac gaaagacgag atttttgtat atgcagttga gaaagaaata
     9421 gaagaaacaa ttaaaaaggt tcataggatt attgccgatg aatcctcgcc ggaacagtgt
     9481 cttagaaaaa tcatgctgaa tcatcttgga gtaccaaagc agtatcgaac ggtgctgatg
     9541 tggttaaata cagaatctga ttatttagaa gaagattatc gaaagcggct gaaaactgcg
     9601 cgttacgcat atcaggatat tataaaatct gtaattgaaa atggaatgga atcaggcgtc
     9661 ttccgtaaga cgaatgccaa tcttatgacg cgtttgttaa ttaactccat tatatcaatc
     9721 atttacacat cccgaccatc agccagtccg gagaaaatgc ttgatgaaac aatggatata
     9781 tttctacatg gaattatgaa tgatggaggt gaattattat gatttattat actctaccct
     9841 tgttgcataa acaggcaacc cttgaaatgg tcggcggaaa aggtatgtct ttatcaaaac
     9901 ttttgacaac gggtattcct gtgccggagg gctttcatgt tacgactact tcatacaaga
     9961 tttttgttga aaagaaccat attcagcctt acattaataa gttgctggac ggtattgaca
    10021 ctaacaatac gagccagctt gaaaatgtat ctacgcagat agggatgctt ttccataatg
    10081 gagaaatgcc gcaggaagta tcagatgcaa ttaaaaccgc atatgccaga ttgggaaata
    10141 tagcggtggc tgtccgttcc tccgcaaccg ccgaggattt gcccgatgct tcttttgcag
    10201 gccagcagga aacctatctt aacatacaag gtgagaatga agttcttgac gctgtaaaga
    10261 ggtgctgggc ttccctatgg acagctcgcg ctattgctta ccgcgtgaag aatgatataa
    10321 agcaggaaat cgtcgcactt gctgttgtag tacaaaagct tgcgttttcc gatgcgtccg
    10381 gcgttatgtt tacgctaaac cctatcaatg gcagacgtag cgaaatgatt gttaacgccg
    10441 cgtggggact tggcgaatcg gtggtttcta gcttagtcac ccctgataca atcgttgtag
    10501 ataaaaatgc tgaacgaatt gtatcgtatg aagtagcaaa caaagagatt atgacagtac
    10561 gcaactcaga tggaacagaa gaaatcccaa ctcctgaaca gttgaggaaa aaacatgctc
    10621 ttactcgcaa tcaagttatg cgattgacac agcttggaaa aaaaattgag aagtattatg
    10681 aaatgcctat ggatgtagag tgggcactgg aaaaagataa gttgtatatt gttcaggctc
    10741 gccccattac tgtcctaccg ccggaatgga cgttaccaga aaaggatgtt atatatacaa
    10801 gaggcagtct agcggaacac ttgccaaatc ctgttacgcc cttattcgcc acacttgggc
    10861 ttgaaatagt caaccgtgcg tcggcgcttt tatggataga tatgtttggt aaaagtgcga
    10921 aaaagctact gccagaaaac ggagcatata cgattattaa cggatatgtt tatctttccg
    10981 ctaattcaaa gcctcttttg attgctgtca aatccctttc accccgatct ttacgccgtg
    11041 cgctcacgaa cagtgttgca cgctgggaaa cagcacgaaa agaatttgag gatgtgatta
    11101 aacaatggga agaaaagccc atgcatatgc tgaatgctca tcaaataatg gaggggattc
    11161 agactgtatt ttatggagcg tgtatttatt tcacgaggat tcagcttaca ttgccagccg
    11221 cctctatcag cgaaacatta tttacaaaat tttttcaggg ggcggctcgt cgcgctggta
    11281 tgacagatac ttctgttttc ctgcttggat ttgatacgat tgctctgcaa gccgaaaaga
    11341 acctgtggag tctctcggaa tgggtaaagc aaaataatac tctcaacctt tatctgcaaa
    11401 gtaatccaac agcaaagata gcggaaaatt ttatgtcctc agttccgcct gacgaagttt
    11461 cactggaagt atggatagaa tggaaaaatc gaatcaatca gtattttaaa gagtttggtc
    11521 gtaccgctta tgaatttgat tttgcatatt ccacaccgca ggaaacactt acaccaacct
    11581 ttgaatcgat aaaaaccttt gtagaaggca aaggtgaaag tcctttttta cgtcaatcca
    11641 aatttgaaaa gcataggaaa caggcagaag aagaaatttt acaacatata ggtagctcac
    11701 gcaaaaaact gtttttgaag ttgctccatt gggcacagga aactgctcct atgcgtgaaa
    11761 atgctattta ttgcatggga atggggcatc ctctgattcg ccagatgttt catgaaattt
    11821 cagcacgcct tatacgtggc ggagctactt cgcatataga tgatatttat tggctcacaa
    11881 aattggaatt ggaaaaactc atagtacagt tagacaaaaa tataccttta tccgatagaa
    11941 gaaattcgat acttgcgcga aaagcggaac tcaaaaagta tcagggctat atgccaccag
    12001 ctcagttacc tgagaagaaa gtaaaaagca tatcacatgc accacagaaa caaaaagatg
    12061 gaaaaaccgt gttgaggggt ataggaacca gttctggtgt cgtgacagct cgtgcctgcg
    12121 tactaaatag tccggcagat tttaaaaatt tccagccagg aagtgttttg gttgccgtta
    12181 ctacaactcc ggcttggaca cccttatttg cttcagcaag tggaattgta acggatattg
    12241 gaggtcctct cagtcattca agtattgttg cacgggaatg tggtatccct gccgttatgg
    12301 cgacacacac agccacgaga agtattaaaa atggacaaat gataacggtg gacggctcgg
    12361 aggggacggt gacgattgat gaataaaaag ccgattttcg ctttaaatct tgctactttg
    12421 gtgattgcgt taggatatag cttaattctt ccggtcatgc cattttacat ggaaaatcta
    12481 ggtgctggcg gtcgtgagct tggatggctc actgccgtat atgccctggc acaaacagta
    12541 tgcgcacctt tttggggtgc actgtccgac cgaattggta gaaagccgat tatcagcatt
    12601 ggtattatag gatattccat cagtttgttc ctgttcggtt tggcttcatc cttttggaca
    12661 ctatttatag ctcgcagttt atcgggtatt ttgtcatctg ctacgtccgt tgcatctttg
    12721 gcatatgttg gagattccag ctcggaggaa gaaagaagca agaatatgag tcaacttgga
    12781 gcttcaatga gcgttggcgt aatgatggga ccattattgg gaggcattct tgcaggctat
    12841 tcgcttgcgc tcccattttt tacaggagct ggcatttcat ttattgcgtt tctgctaatt
    12901 ctaacacttt tgccagagtc aattgagcgt tcaggacaga cggaaaaaag aaaacccttt
    12961 gatttttcag acctgaaaag tataattttt ggctcagcag gaatggtttt gatacttatt
    13021 ttcgtcgtgc atttctgtca aacaggcttg caaggaatta cggggctgta tgtcgtagat
    13081 aagtttggat tttccactaa gcaagttggt gttatttgga tggtgctagc aggtattttg
    13141 attgtagtac aaggcttttt gactggtcct ttagcaaaaa aaattggtga gaagcgacta
    13201 atactgatag gtatgttttg caaagcctta gtagcgtttg ccatggtatt gacaactggg
    13261 tttgttagtg tgttggtggt ttttggctta tttgcggtat cttctgctat tacagtaccc
    13321 acattaaacg caaccctttc aaaaactgac aatcagcata aaggaacact gatgggattt
    13381 gccagtaccg ccggaaatct tagcaaagtt attgctcctt tattaactgg ttatctgtat
    13441 gaaagcaata ttgaattacc atatataacc acgggaggga tagccttaat cggagtggtt
    13501 atctgctata tctggataaa aaatcaaaag aacaaatgat ggaagaggac gtttatatgg
    13561 aggttataca cagtaactaa tctggtatag aaattcaatt gaggcttttc tgctttatta
    13621 aagtcttgct actacttaaa cctataatat ccttaattca ttatgacaaa ttccaattca
    13681 acagttttga tacacataag gaggtaacaa tactatggaa aattatcaat gaagtgctaa
    13741 ttctttatca gtgaagttat ccataagttt ttctacctgt aatcgtctgg tgctttttgc
    13801 cagatcattg gtaggtaaga aaaattcatc aacagacaca tgaagtaatg atacaaggtc
    13861 acttgtatgc ttggatgttg ccctttattt tcaatattag ttaagtaacg tgggtcaata
    13921 tttgtaattc gattttaggg aaatatttaa agaaatattt tcgttttatt tctttaaatc
    13981 ttcaagaata ttgatagttt ttttgaaagt aggtgtgtat tatgaagaat gagaaaaaaa
    14041 ttacagtcgc attgctcatt gtttatttat tgattttatc atggattatt ttatttaagc
    14101 tacaattttc attttctgtg ttagaccaca taagacaaat aaacttaatt ccttttggtg
    14161 gttcagttat tgcaaatgga aaaattgact tcgatgaaat tataaacaat gccattgttt
    14221 ttatccctgt aggtgcatat ttcagtttgc tttttaaaaa taaatctgtt ctaaaagcaa
    14281 taggttctgt tttaggaatt agctttgtat atgagataat tcaatttata tttgctatcg
    14341 gagcaagtga tattacagac ttaattagca acacattagg gggtataatt ggaattgcat
    14401 tagtatatgt attatctatt gttctaaagg ataaaacaca taagatatta aatcgaatag
    14461 caatagtatg tactgtatta gtagttgcct tcttatttat gcttcttgct gtaaataata
    14521 tattttaatg ccatgttaat tacatgttgt tttggaaaag actttaatct gtcaaagttt
    14581 gcttttgaaa ttgaacatga aattacacca atggaacaaa tgaaagctat aaatttttca
    14641 ttggagaaag atgactgtac aagtaaagta ttaatataca atccagacaa atggaaatat
    14701 gtagaatact atttctataa agatagacct attaaaaaac tattggaaaa atttattcaa
    14761 ttttgcattt gtcacaataa aatatgtttt gaaatattga atacttaaat atgcaaaaaa
    14821 aacaaatgta actggctatg gggctatatc tactaaaaag ctatgtgata ggttgggatt
    14881 aaatttaaac atcacttcta gaaggcatga atacacaagg ctgacaaact atacagttat
    14941 gattaaacga taccaacggg attgaaaatt tcgtgaagaa ttttgagaag tcctattaca
    15001 catgagcaac agcaacgaag ctattgaagc aaggacgcag gcaatctagc ggttatctga
    15061 caaaggagtt gtaggacttg aatgtagata ctatcagaac ggatataccg accagctctg
    15121 cggttacaga tgtgattgtg tggaatatcg agcagtcggg aacggacact ttatctgcta
    15181 cctacgaagt agatcagcag ataaaagaga gagaacagac aacagcggtc aaggcaacct
    15241 ataccgtaaa agtccatgtg gacgctgacg gggatatggt aatcgttcag aaccttactc
    15301 ttgcaccagc aatcgaaaaa tcagactatg agccaaagac atcagaaaca gacgcaagcg
    15361 tggacgctga taccgttaat gacgctaccg catttctgga aacattcttt gaggtgtacc
    15421 cgacagccac agaaaaagaa cttgcctatt atgtatcgga aaatgtgatt gaacctatcg
    15481 gcagggacta cctttattct gaattggtaa acccagtctt tacaaaggac ggggacaatg
    15541 tgaaagtcaa ggtagctgtg aaattccttg ataatcagac aaaggcaacg caggtgtcgc
    15601 agtatgatct tgtactccat aaggatagca actggaagat tttaggataa catggaaatg
    15661 ggcttgtatc ataattatag tgtgcaagcc cttttcatat tgaagtatca ataatcaata
    15721 attataatta ggtacatgaa tggagggata aaatgttcaa aattggtgag ttttcaaaat
    15781 tgacacaagt ttctactcgt atgttgcgtt attatgatga aacgggttta ttaaaacctg
    15841 ctaaaattga ttcattaact ggatatcgta tgtattcagc agaacaaatc tcaactttaa
    15901 atagaattat atatttacgt gatagtggct tcaatgtcgc tgaaattgca ttagccctca
    15961 atttcagtaa taatgccatt atagaacagc ttgatagaaa gtctattgaa attatggata
    16021 atatacaaaa agaacaagaa aaactaaaga aaattgagat tgctaaaaaa gaagtgttac
    16081 atggcaaaag tgaattgtat tttaacataa ccattaaaga gataccgagt tattgcgttt
    16141 tatctttaag aaaagaaata ccaaattatt attatgaggg cgaactctgg aaagaactct
    16201 ctgtttttgc taaagaaaat aaaataaata tttctgatga aacattctca atatatcaca
    16261 atgaagaata taaagaaaaa gatgttgatg tagaattatg tgccattgta aataaaatag
    16321 gaaaagctac aggtgatttt aagtttcgtt ttaccgaacc agtttctatg atggcttgta
    16381 ctatggtata tggagatttt tttaatattt cttatgctta tcgttcattt gctaaatggc
    16441 ttcaagaaaa cagtcaatat aagatgaaag gttcaagccg tcaaatagtt catcgtggac
    16501 cgtggaacga gaaaaatcca gagaactatc taacagaaat ccaaattcct ttagaaaatc
    16561 tcttgtaaaa aatgataatc tgccttgact ttaacatggt gttaaggttt atcgtttatt
    16621 tatcaagaag aaaaaggagg aaaatataat gataacttat aaagtgaatt caataggtac
    16681 tatctataat aatgaaaaag gtgctttcat tcaacttgaa gctgcatata tcccagcatt
    16741 aagggcatta gacggattca gtcatataaa tgttttatgg tggttcagtg attttgataa
    16801 tacggatttt agaagtgtat tggaaacaga acagccttat aaaaatgctc cagagaaaat
    16861 ggggattttt gcaacaaggt cgccagtacg tccaaatccg attgctttat cagtagtgga
    16921 aattatcaat atcgattata tgaatggaat gatacaaatt gcttacattg atgctaatga
    16981 caaaacgcct atcttggata ttaaaccata cacaccgagt ttggataggg tggaaaatcc
    17041 aaatgttcca gattggtgta gtcattggcc tcatagttta gaagaatccg cttcttttgc
    17101 atgggaaaac gaatttaatt tttaaggagt gatgaaccat gagtttgcag gattacatta
    17161 ttgaaaaacc agtaattgat acagaacacc ttattttaag aacaatggat aaaaatgaca
    17221 tagatgattt gaaagaatgg attagtgata tttctttata cgagtattgg gggaaacgtc
    17281 cttcaaaaag cgaaaaaaat ccagaagtac tctttagtaa gccagaaaaa gctactaaaa
    17341 gttttcattg gggaattgtc cataaacaag atagcaaagt gattggtgaa atatggatat
    17401 accttattga aaataataga atggcaaaag tggctttcag actttctaag caatatcaag
    17461 gtaatggact aatgagtgaa gcgttgaaaa gcgtaattga attttgtttt tcaaaaacag
    17521 aattacaaaa aatatggaca gatgtgcata ttttaaatca tgcttcttac aagacattgg
    17581 agaaagtcgg ttttcaaagg gaaggacata ttcgaggggg aaaaatggta aatacctatt
    17641 gcgactacta cctatatgga attttaaaat ctgattatat cactagctga tgttatggct
    17701 aatattgaag cgacgattgg cgaagcaatg aacaatacag ttccaaaggt ctatgatacg
    17761 aaaagcatta aaagatatgt gatgaattta ttagatatgg ctcattaaaa agtaccaaag
    17821 aaataaaagt taccatatag acaaaattgg ttttttatat cttttgattt cttataagat
    17881 aatggcattg tgcgacaagc tatacaaaaa attttcatgt atactttgat tataaattat
    17941 acaaggagct aactatatat aaatcaagtg atttttgata attagctgaa atatttttta
    18001 gatcattgaa aagtgaattt tgtgtacact gaaaactact gctttatgca gtactttaaa
    18061 aatattcaat tgaatgcttt taaataagca gtttttcatc aaattgtatg ttttcagaca
    18121 acagtttata gattactctt atgagttttc gtacggaatg cccctgagca catctatggg
    18181 atttaccttg taagcgtttt agtttataat acttattgaa agtgagattg tatttgcata
    18241 ctgtaagaat gcattgatat agactttttc ttaggtagcg cgaaccacgt ttagacaatg
    18301 ctgttcgagg tgcactgtat tcaccggact gataagtacc ggggtctaca cctgcaaatc
    18361 ccatgacttt gacagcagag ctgaagttat gaatatcacc aatctcgctt aaaatcgaca
    18421 ttcccgtata aatcccaata ccgggaatcg agaagatagg agaatctagt ttgacagcta
    18481 attcttctat ttttttgtct acagttttaa gctgactggc taacagttcg atattttcaa
    18541 taagcatttt gatttcaagg gtaacagctt cgttgttttc gccgatagat ttctttgcac
    18601 tggaacgaag agatgatgca tctatattca cacggcttcc actgctttta ggcttgagaa
    18661 cttttttaag atgagcaaga ttggcactgg ctaaattata agaacttcca aattctttta
    18721 agacagccat ataagctttg gaatatttag ttttaaacca agtattgaac tcaggaataa
    18781 cgatatcaat acatttctga agttggtttt tcttctggtt gatatcttca gcaatagaag
    18841 catgataacg ggttaattca cgagcctgtt tcatatcgag cttacgctga gtgactctag
    18901 tataatctct atcaaagagt actgaacaaa taagaaaagt atctttttta tcattcttag
    18961 tctttcttat tttgcttttg cgcttggcat cagttgttaa tggatttatc aaagcaactt
    19021 cataatcatg agtgattaaa aaattaataa gattatcacc gtaatgaccg gtagcttcta
    19081 aaccgacaat atgtctaggt gatttaaatt ttttaacagc tttgataaaa gaatcgaatc
    19141 cgtctagatt attagtgaag aaaaaaggtt caataaggac ttcaccttca gaagaaataa
    19201 cgcaggcaca gtgattgaat ttaccaacgt ctataccgat gtaaaacata aaaagcacat
    19261 cctttcttta tataagatag tgatatgtga ttaaaccaca aacagagtat caaagagcct
    19321 ggtgcaaaat acaaattcga agacttatct aactgatcac aattaagata caaagatgtg
    19381 gcaataacct ccttcaagta gtcaagctac aggtgctgaa agaaaaagta cacattcaca
    19441 attcaattct aaacaaaatt taatgaaagg aaaaggtgta tataattgac agatagataa
    19501 gtcaattaca atataccagg tactgatatg tacgcatatg aaaatattga aatgtcatta
    19561 aactatattg aacaacattt aagtgagaaa atcgaaacag agaaactggc ggaaattgcc
    19621 tgtctttcta cattttatta ccaacgcttg tttaaaaagt tagttaagaa atcagttcaa
    19681 gagtatatca aacttcgccg tttagcaatg gtaatagcag aattgaataa ttcagaggaa
    19741 agaatattag acatagcttt aaaatatgga ttttcagacc atgctaactt cacaagagca
    19801 tttaaagaag tttaccatat tactcccgat gaatacagaa agaatgttcc tatgttaaat
    19861 acatttgaca agccagaact ttcttcacgt tatatcatga ttgatgaaaa tgtcccattg
    19921 attgtaggaa atattgtttt ggaaattcaa agaaaaacat taagaacaaa ggaaacatat
    19981 tttggttttg aaaaaacagt aaatattgct gaacaaattc ctgctggaga aagtacagga
    20041 attgatgttc caggtcagct atggcgcgaa ttccatgcaa agaaactgca aaccgaaaat
    20101 gccattttta acaatgatat tgaacttggt gtatctcact tagcaagtcc agataaagga
    20161 acattccttt actttgcagg aggtatggtt tcatcaacag atgtatgtcc taaaaatatg
    20221 gtacaacata cattaccagc aggtgagtat attgtatgca aaattgaggc agaatctttt
    20281 gaagaacttg ttactactgc tttaaatcaa gcaaataagt atctgtttga aacttggctt
    20341 ccaaatcata atttggttac aaagccattc atggcagaaa aatattacaa aggaaatgca
    20401 gagattaatt atatggaagt atggataatt cctgtgtaaa cagtaaatgc taaataggaa
    20461 ttatctgacg taataaaaag gaaatagaaa gcttataaag gagggcatag tccgttgtga
    20521 taaacataaa agatataaat tatgtaccta atattagtga aataagcgtt tatattgaaa
    20581 actctgcatt tgatgagttg tatcagcata tgaacaatga atataaagca gtttgcaaaa
    20641 tcgaatacag taaagatgtc tgggcacgag gttggaacgt aaagtttaaa aaatctggga
    20701 aatcattgtg tgttgtctat ccgaagaaga actactttac tgtattggtg gttgtaggta
    20761 ataaagagaa agaagatgtt gaaaacttgt tacctaggct ttctgaatat gtacaggaaa
    20821 tttatcgtaa cactagagag ggaaatggac aaaggtggct tatgatagac ttaaaatcta
    20881 aaaataatgt atatcaagat gtattaaggc ttattgaaat tcgttatgcc ataaaatgtg
    20941 taaaaccgta ataaaaatat ttttcacata cgtaatctca aggtattatc gttgagacaa
    21001 gtaacctata taattatggg aaatgagatt tttagatact taagaaagta ctttaggggg
    21061 cttgcgttat ggaaagattt aagtacaatt ccacacaatc aaatacaatc taataaagct
    21121 ttactaaaaa ttgaatgcat tacagcttta aaggctcgta caaactatat gttttgtgcg
    21181 ggcttttttc atttaatagg aatttggatt cgtcagagag tatattataa aaataaaacg
    21241 ataagggtac cttaaaaata aggtacctca ggctgtagac aaagtcccgg actctcgtct
    21301 gggcttttct tatatttgag ttatccacaa ttcaactttt taagagttat cttattaaga
    21361 aaaaagtgta tgttttccac ccgatagttt tacttctgtg atatttgcag atgccactca
    21421 agtagaaagt ggtggtacgg cagaagatgt catgcagagt tcagaaagtc tgggactacc
    21481 gcctaattcc ttagacacgg aaagctcaat caagcagggg tgtaagtatt ttgcgtccct
    21541 gctttcttcc tgcaaaaatc aaggtatcga cgatttgaat gtagcgatac aatcttacaa
    21601 ctatggcggg ggttatgtgg gctatgtggc aggaaaaggg aaaaagcaca cttttaatct
    21661 tgcagagagc ttcgcccgtg agaaatcggg tggaaagaaa gtaacctacg ccaacccgat
    21721 agccgttgca aagaacgggg gctggcggta tggctatgga aatatgtttt atgtggaatt
    21781 agtcaatcag tatttaactg ttccgcaggt gtcgggggaa ctggcacaaa aggtaatgaa
    21841 tgaagcgttg aagtatcaag ggtggaaata tgtgtttggg ggaagcaatc ccaacacttc
    21901 ctttgattgt agcggacttg tgcaatggtg ctatggaaaa gctggtatct acttaccgag
    21961 aacggcacaa acacagtatg acgcaaccca gcatatccct ttatcgcagg caaaagctgg
    22021 ggagttggtc tttttccatt caacctataa cgctggttcg tatgtaacgc acgtcggtat
    22081 ctatgtggga aataatcaga tgtaccatgc aggcaatcag cggttatcta acaaagaaat
    22141 tgcaggactt gaatgttgat actattagaa ccgatatact gactagcccc acagttacag
    22201 atgtaattgt gtggaatatc gaacagtcgg gaacggacac tttttctgct acctacgaag
    22261 tagatcagca gataaaagag ggagaacaga caacaacagt caaggcaacc tatacggtaa
    22321 aagtccatgt agacgcttac agggatatgg taattattca gaaccctacc cttgcaccag
    22381 caatcgaaaa atcggactat gagccaaaga caccagaagc agacgcaagt gtagacgctg
    22441 ataccgtgaa tgacgctacc gcatttctgg aaacattctt taagctgtac ccgacagcca
    22501 cagcaaaaga gcttgcctat tatgtatttg gaaatgtgct tgaacctatc ggcagggact
    22561 acctttattc agaattggta aacccagtac ttacaaagga cggggataat atgaaagtca
    22621 aggtagctgt aaaattcctt gataatcaga caaaggcgac gcaggtattg cagtatgagc
    22681 ttattctaca taaggatagt aactggaaaa ttattatgta agacattttg ttggcaggat
    22741 ctattttcgg atatagtctg ccttttctgt agcaaatgta ctgcactgac aagctatttc
    22801 attgtatttt aagcaattaa atctttcttg acaattttat cttaaatcat atatttatgg
    22861 atattgactt tctgcttgca ataagttata atatgactat aaaaccaaat tagtcacata
    22921 ggaggtatgt ggtatgtata aagaagttgg tatttcttca aataatgttc cgataacact
    22981 ttctatctgg tatacagaaa gaagtagtcc taccattgtt tttttgccgg gtactatgtc
    23041 acaccctctc atgtatgaga attttctatg tggtttgagt gaaagaggat ttaatataat
    23101 aggcattcac tatctttcac acggaaaaag ccctaaaatc aaaaaaaatt atacaatgga
    23161 agatttgctg cataatgtat atgacgcaac aacttacgga atagaaaatt tcggtgaaaa
    23221 catagctgtc atgggttcca gtcaaggcgg gattttagct gcaatggcgg caggtaggga
    23281 cacaaggtta aaagccgttt ttccacataa tatcatgctg actacattaa aagaaactat
    23341 gagcttaaca aaatatccca catggtcgca ccgttttatg gggctgatac agtggggctt
    23401 tcgtgtaggt ggaaaattgc tgcctaacta caaggttcca ggagacgctt atttagacta
    23461 tgacagagta ttttatagtg aacaggcaaa acaagattgc ttaaatgacc ctatgctttt
    23521 accctattat cctttaagat ttgtcgccag cttatttaat gctgacttat cgtgcctgga
    23581 gaatggggct atacaatgtc ctgttatttt aattactgcc aaaggcgacc cgctttttag
    23641 ctttgattat accaacaaag tatttgattt aattcatgta ccgcaaaagg aattacttgc
    23701 tttagagctt aatcgtcaca tgatttttaa tgaggacacg gacactacaa taaacgcatt
    23761 ggaagctacc ttgcataaat atcttggata gcatattgat tatataatca gtaaatgtta
    23821 tacttttcat gacgatataa atattttagt cataaggagg ttatgagttt gccacgattt
    23881 acggaacaag aaaaagaaat cataaacagt aaacttttga tagagggaga aaagctgttt
    23941 gcattacacg gcttaaaaaa agtaacagtt gatgatttag tagctgctgt aaacatatca
    24001 aaaggttctt tctatgcttt ttatcccagt aaagaacatc tatatgttga aatcaatttt
    24061 cgcttacaaa aagagttatt tacaagtata gaaacaacca ttaaaaagaa aaagtataag
    24121 aaccatagag atttagcaaa ggacgttatc atgctaagtt taacgggggt gattacttcg
    24181 cctattcttt cacagattga tttatcttta atggactatc tgcaaagaaa aatatcgtca
    24241 gatatttttg aaaatcatat gtacagtgat attcgtatat tggagatatt ggaagattta
    24301 ggggttgtat ttttggttcc gcatacggtt attataaaat ccctgtattc tgttttatcc
    24361 tgtttggaac aattcaaaga ggacgaagaa ctgaatatga tacaaaatct tttagtgaat
    24421 ggtattattc agcaagtagt agcagagtaa caattttgtt tggttatttg acaggcaggt
    24481 agccaaacaa attttttaca gtttatatga ctatatatct ataagcgtca taaagttaaa
    24541 ggaggaatga ataatgattg atgtaaaaaa actgtatttt agctatactg acaaaccgtt
    24601 tgtggagaat gtaagtttcc atgttgggag aggagaaatt tttggttttt taggaccctc
    24661 tggtgctgga aaatcaacta ttcaaaaagt tttaactggg cttaatacaa gatataaagg
    24721 cagcgtaaaa gttgcaggta cagaaataag ggagcataca aatcagtttt atgaaaatat
    24781 tggggtagac tttgaatttt caacctgcta cgagaaattc acagcacgac aaaatctcgc
    24841 ctattttgct tctctatatg aaaagcaacc tcggtctatt gatgaattat tgcatatggt
    24901 aggcttggaa aatgacgggg acaaaaaagt tgctgacttt tccaaaggta tgcgttctcg
    24961 cttgaatttc attaaagcgt tagtccatga ccctgatata ttattccttg atgaacctac
    25021 aagcggtctt gaccctacaa atagtcgttt aatgaaagat attattcttg cagaaaagaa
    25081 acgcggaaaa acgattatca ttactactca caatatgttt gacgcaacag agctatgtga
    25141 ccaagtagcc tttatcgttg ccggaaaagt cagtgcattg gatagcccgc ataatttgat
    25201 tatgtcaagg ggagctgcca aaatacaata tacctactat gataaaggcg agaaaaccgg
    25261 agaatgtctg cttgatagaa ccacagaaga taagttgtta aaaagtttaa tttccgaaaa
    25321 ccgtttgctt tctattcata gtagtgagcc tacattaaat gatatttttg ttgatattac
    25381 agggaggaca cttcaatgag attgggacgt ttaatttgtg gtgatataca tttccaatgg
    25441 aaatatggtt tctattttat ctactttata ttaacagttt tatatgtgtg cgggattgcc
    25501 gctttgccgg aacattggaa aacggatatt gcttctatta tgatctactc tgacccggca
    25561 gcaatgggat tattttttat gggagcgatt gtcctcttag aaaaaagtca aaaggtgtta
    25621 aatgctatgg tagtatcgcc tgtaaaagta tcggagtaca tactttcaaa aacaatcgcg
    25681 ttgattgcta tttctacggt aatcgcattg atattagggg tagtttccga cagcaatcat
    25741 ttacttggta tcacagttgg tacggctttg acctcagcaa tctttactat gcttggaatt
    25801 attgcagcta caaaaatttc aaacttgaac caatttctca ttgtgattat gccgatagaa
    25861 attgtttgct ttgtaccacc tattgttggt ctgtttgtga agttaccata tctgttccgc
    25921 ttttttccat tcacagcttg catgaacctt ataactggaa aaagcgtttt actatcgttt
    25981 gatatggtac ttgtaattgc tacgttgatt atcctctaca tagttgcgcg acatacagtt
    26041 aagcatatgt ggaaaagttt aggaggtgta aagctatgaa aaggatatta tccagtacca
    26101 tacaggtatt tagacaaatc aagagtgacc ctatgatgtt tgcagcttgt tttacgcctt
    26161 ttgtcatggg agctttgatt aaattaggta ttccctttct tgaaagaata acggattttt
    26221 ctttgcaagc atactatccg atttttgatt tactactttc tatcatggct cctgtattac
    26281 tctgctttgc atttgcaatg attacattag aggaaatcga cgataaagtg tcacggtact
    26341 tttcgattac ccctcttggt aagtcggggt atctctttac aaggttggga gtaccctcaa
    26401 ttatttcggc ggtcatcgct tttattgtac tgttactttt ttcattagaa aagttgtcca
    26461 ttggaatgac aatatgtttg gcgcttctcg gctcagtaca ggcaattatt gtttcactta
    26521 tgattatcac attatcaagc aataaattag agggtatggc agttacaaaa ctagctgcac
    26581 ttacattgct cggaatacca gccccctttt ttattgatag ttactaccag ttcgcggttg
    26641 gcttccttcc atcattttgg gtagcgaaag ccatgcagaa tgaggcggtt ctttatttct
    26701 ctataggatt ggtggtagct ttagtctggt actacttcct tacaaaacgt ctgtttcgga
    26761 agctggcagg ataaggaggc atattatgga aaagggtaga cttctgcaaa acggaaaagt
    26821 aaatagagct attcaggttt ccaaaatcac actatttatc aacctaagtt tatcgttact
    26881 taaatttact gccggatata taggaaagtc aagtgccatg ctgtcggacg ctgtacactc
    26941 ggcttctgat gtattaagca caatcgttgt gatggttgga attaaaatat cagaaaaaca
    27001 gcctgataga gaacatcctt atgggcatga acgtatggaa tgtgctgctt ccattattct
    27061 ctctgttgca ttggccataa caggtgctgg aattggatat tcaggtatca agaaaatctt
    27121 ttcagaacag tacaatacgc tttctactcc tagtggaatc gcacttacgg cggcagtctt
    27181 atccattgtt ataaaagagt ggatgtactg gtttacaaga aatgctgcaa agcatacaaa
    27241 ttctgacgca cttatggctg acgcatggca ccaccgctct gatgcactct cgtcggttgg
    27301 ttccttaatt ggcattttag gagcgcgttt aggctatgct attctcgacc ctattgcaag
    27361 cgttgtgatt tgcggttgta tcttaaaagc tgctttggac attttcaaag aaagcattaa
    27421 caaaatggta gaccatagtt gtgacaatgc tactgaaaca aagattaggg aagttgtgct
    27481 tcagcagcaa ggggttgatg gtattgatga attaaaaacc cgcatgtttg gagcgaaaat
    27541 gtatgtagat attgaaatat tagctgatgg taatttagct ctttatgacg ctcatagaat
    27601 tgctgaggga gtccatcaaa cgattgaaaa caactttcca caatgtaaac attgtatggt
    27661 acatgttaat acgaatgaac ttctctattc tgcataggac agggaagatg atttaaggct
    27721 attgaaaggg aaaggaggga agtaggttat ggaacaatac tggtggatta tcattgttgt
    27781 ggttttgatt gtcgttggtt tacttaaaat tgtaattatg aagaagtata accaaaggag
    27841 aaattctaac aatagtccaa aagatagcga ggacgacaag atgtattaag gtttattgaa
    27901 atctgttatg ttgtagaatg atgtttttag atactagaaa gtgctttaag ggggctaacg
    27961 ttatggaaag ctttgagtac aattctttcc aatcaacagt attttgcata gagaaatgta
    28021 tgtaggaaat atggtgcaag gcataaagca ccagcgatcg agagatcaac ctatgaacca
    28081 aaggcacact acattttata ctacttgaca agtaaacgag cgtttactat aatggtttac
    28141 agaagtaaac gttcgtttac taaagaagga ggttgtaaat gtctgacaca aaagaaaata
    28201 tattaaaaat tgcactacac ttatttgcag tgaatggtta tgaggctgtt tctgttagta
    28261 tgattgcgga agccttggga atgacaaaag gagcattata taaacattat aaaaataagc
    28321 aagatatttt tgactgtatc gtagaacgta tgtatcaaat tgataataag cgagctaagg
    28381 attatcaagt accagaaagc acaatagagg taacccctaa tgcatacaga aatacaacta
    28441 ttggaagtct aataacattt actcttgcac aatacgattt ttgggtgact gatgaatttg
    28501 cgtctaattt tcgcaaaatg ttaatactag agcaatatag aaatttaaaa gtgaatatgc
    28561 tttatcaaaa atgtcttgta aatggtccta tcagttatat agaagatata tttaatgaaa
    28621 tgattgaaaa aggtgttctt caagagtgtg atacaaaaca gcttgctatt gaatattatg
    28681 cgccattatt tctattgata agtgtagcag acgcagttga aaattgttgg gatttaaaaa
    28741 ctcaattaac tacacacgtt aaacaatttg tcaagaaata tattataaat gagaaagtaa
    28801 aataatcctt tattctgtcc taaatataaa cctaactttt taatttcagc agagaaactc
    28861 aaaatgaaga ttgttataag tcacaaatat taactattaa aatattacaa taacggagat
    28921 gagaaaatgg aatatattcg cagtaaaaaa tattttacac ccgacttaca gacaaaaatt
    28981 atggggccga atcctataaa attacaagag gaactattac aaaatcataa aatcccgtct
    29041 ggtagctatg tctgtgacct tggaagtgga caaggtttaa cttctgtatt tcttgcaaaa
    29101 gaatatggat ttgttgtttt tgcagttgac ttatggagtg agccaaaaga aaatgaagaa
    29161 tttttcaaaa aaatgggatt atcttctgca caaattaaat ctgtaaaagc tgacgccaat
    29221 gaacttaaat ttgagaaaga gttttttgat gctgtagtaa gtacagattc atataattat
    29281 tttggacgtg accctatata tttagatgaa aaattgcttc catttgttaa gaaaggtggg
    29341 tttgtttata tcacagttcc tggcatgaag aaagattgcc atgagaaact tccagaagag
    29401 ttattgttat catggacacc agaagaactt gattatatac atgatataac atattggtct
    29461 aacataatta gtcattgtaa aaaggcagat ttaatttcaa tatatgaaat ggaaagtaat
    29521 tcggaagttt ggtcggattg gataaagcaa aataatgaat atgcaataaa tgaccgtaag
    29581 gcaatagaag ctggcggtgg agattatctg aattttattg ctataattct acaaaaaaaa
    29641 taaattcttt agaaccaaac actataattt gcgttctaat atgtttaccg attgacatca
    29701 ataattttat ttttgagggt aatgatttga aaatagaaga ataattccag tttgtaaaag
    29761 tcaataaatc caaagataaa tttgtatttg aaaggagttt tgaaaaatga aaaaatatga
    29821 gtatgtagaa attaactata atgcgaaagg agttgtattc ctttgtactg ataaacacaa
    29881 agaaattatt gacagttacg caaaaacggg gtatcactac gcagggtttg tacccacaga
    29941 aattgacgca aaaggctgta tgcgaaagat agatttaatt tttgaaaaag aagattaact
    30001 tattttaggg agttggttct aatgatagga cttaaaagac gaaatatgaa ttatattatg
    30061 aaagttggtg ctaaagctca aggtgtttct gtatctgaat ttagggctat gctacaagat
    30121 accatagaca aaactatgga aagtacagac ccagacgtgc aggcaaattt taaacgatac
    30181 tttggaaata agcgcccaac accagaggaa tatatttata cgattaccaa aaagacaaag
    30241 gttaaggttt aaatgttgta aagggggctt gccgtatgaa acgctttatg tacaattcag
    30301 tatattcaag cccaatttaa cagcatacta tttacaatta aatacgctat accagtagct
    30361 cgtacaaaat ttatattttg tgcgggcttt tttaataccc gaaaagtttt tttaattatt
    30421 ttcatttttt tggaagcaaa tcacaccttg ctgtacagat atggtgcgga aagagggata
    30481 aacacttttc aattcatagc tggaaaggag gtgagattat gaaaccgtct gacttccaaa
    30541 aaacaattca gtgtcagttt gaatgtaagc tgaaaaaagt tgtcaaaggt attatctgga
    30601 actaccgtaa agaattaaaa cgaagaaaaa acaaggaaat atcttttagc gaattaccag
    30661 acattacggt agaaagtctg gcaacatggg acgactacga aacaaactac acaattttta
    30721 atgtgtgtgg catagatatt aaagtccttg atgatgaact tgcagaagct ctcaaacagc
    30781 tacccgaaaa aaaacgtaac aatgtattga tgtattactt cttggaaatg agtgatacag
    30841 agattgcaga tattatgaat tataccagag gggctgtgtt caaacacaga caccgtgccc
    30901 tagaaactat gaaagagata ctaaaggaga agaaatagaa atgaagaaaa agtacaagca
    30961 cccgtcttat tatttgattt catcagctat ggacggggat gaaactgcga ttgagaaatt
    31021 actggtattc tatgacccgt acatatcaaa gtgttgttta cgtcctttat atgatgaata
    31081 cggcaatgtt tatattgttg ttgatatgga attaaaggga cgtattcgag aagccttaat
    31141 caaaatgatt ttagactttg agattgatat agatatagaa accgaagaag aataagcaga
    31201 taccagcagg gcgtgattgg ttaaacctcc tctttcctgc cctgctcctg cttttataca
    31261 tggaagccta cggctttcgc cgattgttct ttgacaactg aataaagcag acagatacgt
    31321 ttgtgataca gcgagccacg gggactgtac gccatgacct ttccgacaag aaagtgagcg
    31381 acccacgcag tgatccgaga gcaacttgtg gaatggtcgc tttgccatga cctgctatca
    31441 cagaataatg atacgtccgc atggtgcggt tctgcccaca agaatgggaa tagttgagat
    31501 actaacggag ctttccgaag ccgtctgtct gcttatgata agacatacag aaaggagtgt
    31561 tgcaacatga acaatactga tgtgcctatc tgggaaaaat atacccttag tatagaagaa
    31621 gcgtcccgat attttcgtat cggggaaaag aagttgcgta ggcttgccga ggaaaatctg
    31681 gactctggct gggttatcgt caatggaaac cgtattcaga taaaacgaaa acagtttgaa
    31741 aaaattattg atacactgga cgaaatctga tgtcttagag ccgtagatat ggtataatat
    31801 tagtagcgta tcacggctca ttccatgacg gaaaggagct ttacaccatg tcaaaagtga
    31861 aaagacaaga cagtaaagga cgcaatttgc gtcttggaga gagccagaga aaagacggaa
    31921 gatacgttta taaatatacc gatatattcg ggaagccaca gtttgtatat gcttggaaac
    31981 ttgtacccac agacaaaaca cctgctggaa aacgtgatga tatatcgttg agggaaaaag
    32041 aaaagcagat aaaaaaagac cttgacgacg gtatcgacac agtgggtggt aaaatgacag
    32101 tctgccagct ttacgaaaag aagaacaatc aaagaaagaa catcaagaga aacacaaaaa
    32161 taggacgaca gtatcttatg aacgcactgg aaaatgaccc attgggtatg agggcgattg
    32221 atacggtcaa gcagtccgac gctaaagaat gggctatcag aatgaatgac aaaggttatt
    32281 cctacaaaac gatagataac tataagcgtt ccttaaaggc ttcattctat atggcgatac
    32341 aagacgactg tatcagaaaa aatcctttca atttcaagtt gagtgatgtt ctggaagatg
    32401 atacggaagc aaaggttatc ctaacaccag agcaggaaga aaaactcctt gcctttatgg
    32461 aaacagataa tgtctacagc aagtatcgtg atgaagttat tcttctgctg gaaacgggac
    32521 ttcgtatctc tgaattatgc ggactgacaa cacacattga tatgcttaac cgtgtgatta
    32581 acataaacca ccagctattg cgtgatacag aggtgggtta ctatatttcc acacctaaga
    32641 caaaaaacgg gaagcgtaag cttccattga cagaaagagc atatcaggca cttgaacgaa
    32701 ttttaaagaa ccgaggaaaa gcacaaccgc ttgttgttga cggttacagc aacttcttgt
    32761 tcttgaaccg tgagggattg ccaaaggtgg caggaaatta tgaaagtatg gtgcgtgggc
    32821 tgattaagaa gtacaacaag acgcataagg acaagttgcc aaacatcacg ccccattcat
    32881 tcagacatac ttactgtacg aacatggcaa ataagggaat gaaccctaac accctgcaat
    32941 acatcatggg gcacgcaaac ataaccatga cattagggta ttatgctcac ggtactttcc
    33001 agtctgcaaa ggctgaatta gaaaggctgg cttcttaata tcgaaaatgt atcttactac
    33061 ttatttacta cttttggttg cattttcatg ctggtaaatg ccatcttatg cgaggtatct
    33121 tccaaaagga aaatgccaat aaagcccgaa aatatgggat atatcggcat ttaccaactt
    33181 atgaaaagat aatcagaaat ttagtaagtt tttatatcaa aaatagtaat aaagtctata
    33241 tacatttaga aaatactgtt taaaaggagt aggatttatg ataaaaaaag agatatctaa
    33301 ctttagagga agtagtgatt atgtagtatc accagaattg atggcatcag ttaatgttgc
    33361 tattgctctt gaaaagccac ttttgattaa gggcgaacct ggaacaggta aaactatgct
    33421 agcacaagca atttcaaatg aattaaaaaa agatttagta atttggaata taaaatcaac
    33481 tacaaaagca caagaagggc tttatgtata tgatactgtt caaagacttt atgatagcca
    33541 atttggagga gaaggtgtag atgatattag caagtacata aaatatggta aactaggaga
    33601 ggcctttagc tcaaatcaac aagtaattct tttaatagat gaaatagata aggcggattt
    33661 agaatttcca aatgacttgc tttgggaatt ggataaaatg gagttttaca taaatgagac
    33721 aaaagaaact gtaagagcta aacaaagacc aatagttatt ataacttcaa atgcggaaaa
    33781 agaacttcca gatgcttttt taagaagatg catatttcat tatatagaat ttcctgatag
    33841 agacatgatg gaagaaatag ttaaagtaca ttttgataaa gtagaagaac acctattgga
    33901 acaagtaatg actacttttt attggattag aagtttaaag gacatacaaa aaaagcctag
    33961 tacatcagag ttaatagact ggatacaagc attaactttg agtggaatgc ctattgaaaa
    34021 aatagaaaaa gaagttcctt ttgcaggaat actacttaag aataatgagg atattgaatc
    34081 tatgcaaaga cacttatagt taataggagc tggataatta tgtttattga atttttttat
    34141 ttattgaggt caagaggatt aaatgtatct ttaaatgaat ggatgacttt aattgaagca
    34201 ttggataaag gactgtgcta ttcaaacttt tcaaattttt actatctttg caggatgatt
    34261 ttaataaaaa gtgaaagtga ttttgataag tttgatgcag tgtttttgga gtattttaaa
    34321 ggtatagaac accaagaaga aattccagaa gagattatga attggcttaa aaaaccagat
    34381 atagatttag aagagtttga aagattagaa caaaatccaa atataaatct tgataaatta
    34441 agagctaaat tggaggaacg aataaaagaa caagactctc ctcataatgg tggtaattat
    34501 tggataggca caggaggcac ttcagagtta ggacattcag gaaaagggca aactggtata
    34561 cgtataggtg gaaattctac ttatggtaga gctgttcttg aagttgcagg agaaagaaaa
    34621 tacagagatt ttagagatga tgaagtttta aatatgcgtc aatttcaagt tgcactaaag
    34681 agacttcgtc aattttctac cagaatagat gctccaaaga cagagcttga tttggataag
    34741 actattgaag agacttgtaa taatgcagga tatttaaagt tattttttga gaagccaaga
    34801 aaaaatacag tgaagctttt attgcttatg gattcaggtg gttcaatgag agggtatagc
    34861 actttatgta atacattatt tcagtctgta agtaaatcaa atcattttaa agatgtaaag
    34921 atatattatt tccataactg tatttatgat agattattta caacacctga atgttggtta
    34981 agtaaatcta ttaatactga atggatatta aaaaatatag ataaaaacta taaagttata
    35041 attgttggag atgcttctat gtcgccttct gagttgcttc atattggtgg taactatcgt
    35101 ggtccatata attacacacc tggtatagag tggcttaaaa ggtttaagag aaagtacagt
    35161 aaaattgtat ggatgaatcc agaacttaga gatggatggg attcaattaa ttattggtat
    35221 caaactcaaa gaatgataca aagtgaattt aatatgtttc cattgactgt aaaaggtctt
    35281 gagaaagcat tgaaaaattt aatggtttca agataaagta aatataaatg atggtatgat
    35341 ttattcaaaa ttgtaccatc attatttatt ttttttaata tatctattat aaattgtata
    35401 actgaaactt aaaaaattat atagtctaat acattttaga ctcacacaaa acatatacat
    35461 taataataat tttagaagtc gaggtgatta taataaatta tgaattaatt gtaaaataca
    35521 atggagatat attgaggtta gaagaagaat taggtgtatc agtagagata cttaattcat
    35581 catatgcaat aataacatca agtaatgaag aagatgtaaa tatactttta acttatccag
    35641 aaattgaatt tatagaaaag ccttttatat tacagactca ggatgtgcaa agtttttcaa
    35701 gtacaggaat aacaggattt aaaaatagaa ctggtttaac tggaaaagga actataattg
    35761 gtataattga ttcgggaata gattatactc tacctgtgtt tagagatagt gatggaaggt
    35821 ctaagatatt atattattgg gaccaatcta ttcaaggaaa tccaccagaa ggttttagag
    35881 aaggaacatt atatactaat gaagatataa ataatgcaat agatggaagt atgtatatac
    35941 ctatttcaac aactagctta catgggacac atgttgcagg tatttgtgca actattgcaa
    36001 gtgatgccag aataatagtg gttagagttg gaaatataca gaccgatatt ttttcgagaa
    36061 gtacagagtt tatgagggca attaaattta ttttagatag ggcattagaa ttaagaatgc
    36121 ctgttacatt aaatataagt tatggaagta atgaaggttc acatagagga acatctttat
    36181 ttgaacaata tatagatgat atgtgtttat tttggaaaaa caatatagtt gtagcagctg
    36241 gaaataatgc agataaagga ggtcataaaa ggattaggct tcaaaataat attacagaag
    36301 aagttgagtt tatagttggg gaaggagagc gtatattaaa cataaatata tggccagatt
    36361 ttgttgatga ttttagtgta catttggtaa acccatcaaa taatcaaaca caagcaatct
    36421 ctctaacttc aggtgagata aggaatactt tgggtgaaac tagaataact ggttattttt
    36481 accctatagc accgtattct ctcacaagaa gagttactct acaattaagt tcaaatacac
    36541 agataactcc tgggttatgg aaaattgtat ttgaaccaat agatatagta actggtaatg
    36601 taaatatata tttgccaact tctgaaggtc tgaatagaaa tactagattt ctgattccta
    36661 ctcaagagct tactgtaaca gttcctggaa cagcaagtag agttataaca gtaggtagtt
    36721 ttaattcaag aacagatata gtatctatat tttctggtga aggagataca caattaggtg
    36781 tttttaaacc tgatttatta gctccaggtg aagatatagt atctttttta ccaggaggta
    36841 caagtggagc attaactgga actagcatgg ctacacctca tgttacaggg gtttgttcat
    36901 tgtttatgga atggggaatt gtaaatggaa atgatttatt tttgtattca cagaaattaa
    36961 gggcattact tctaaaggga gcaaggagat taagtaatca atcttatcca aataattcat
    37021 caggatttgg ttttttaaat ttatcagata tagatttgta cactctatct aatataaatc
    37081 aagatttaga aacagaggat attggatata gaagtattaa taagtcattt aaagatgagg
    37141 aaaatagtta taagtttata gatggttata atatgcaaat acataatgac ttagagaatg
    37201 aaatttatat aagtaaaaat gcaagtagac aatcaggaat actatcagga atagatatag
    37261 tccatactcc tgaatttgaa gaagaactag ctgggttagg tatgagtcaa aggtttttta
    37321 agataagtga ttcattaggt gtactatcta taaataatac agactataat agcatacaac
    37381 gagttttgca acttccttca atcataagaa ctgtatcgac tacaaagatg acattacttg
    37441 gagaaattaa tcgaggtact tttggaggtg tagttgcaac agaagaaatg ggcgtaaatt
    37501 tctttaaaaa taatcctaat attaatataa caggaagagg gactctaata tcaattgcag
    37561 atacaggaat agactatcta cacccagatt ttatttatcc agatggcact tcaaaaatag
    37621 tatatttatg ggaccaaaca aaagaaggaa ctcctcctga tggtttttat attgggacag
    37681 aatatacacg agaagatata aatcgagcta tcgcagaaaa tgaccctagt ctatctcagg
    37741 atgaagttgg tcaaggaact atgttgagtg ggatatgtgc agggcttgga aatgtaaata
    37801 gtgaatatgc aggtatagca gaagattctg agctaataat aataaaactc ggcaagatag
    37861 atgattttta taatagtgca atgttgtttg ctgcatctca gtatgcatat aaaaaagctt
    37921 ttgaacttgg aagaccatta gttataaata tgtctttagg taccagtagc ctagcaggtt
    37981 taaccaatag gagtaatagt gaaaaagcgt tctttactag agggttatgt ataacggcag
    38041 gagcaggaaa tgagggcaat acacagacac atacatctgg aataatacca tatgttggag
    38101 gttctgttga agttgaatta gagttaaatg aagacgagga agaattatca ttagaacttt
    38161 ggttaaatag accagataaa gctgatgtaa taatagtatc tcccactggt gaagaaagta
    38221 aaagtgttgg aatttcaaat tataataaag taacaggttt atttgattta gaggggactg
    38281 aatattctat aacatatata tacccaacaa ctttttctgg acagcaattt actaatgtta
    38341 ctttaaagaa tgcaaaaaga ggtgtatgga agattcgatt agtaggagtt tatattataa
    38401 caggaagata taacttatac cttccaaata gagaactttt aaaaagtgga actagattta
    38461 gagaggtaga ccctttttac actataaatt atcctgcgat tcaagatgat ttaataacca
    38521 taggagccta caatactatt aatggtagtt tatggcaaag ttcatcaaga gggccaacta
    38581 ttgaagacag gttaaaacca gatatagtag caccaggtgt caatataata gctgcttatc
    38641 ctgggaacac gtatgcaact ataactggta cagcagcagc aagtgcacat gcagctggtg
    38701 ctgctgcaat gtattttcaa tatacttttg ttgacggtag atatccaaac caagcatatg
    38761 tgcaaaaaat aaaaactttt atgcaagctg gtgctagaaa agattcaaac acagtatatc
    38821 caaatacaaa ttctggatat gggctcttgg atgttagagg aatgtttgat gttttaagat
    38881 aggagggatt tatggaaaaa tcttattgta taatttatca aggtgatata gaatctgccc
    38941 tacaagaaaa tggaataaat aggtatatgg ttttaaatag tcagcttgca gtaatatatg
    39001 tacctttaga ttttgatgaa actattttaa ataatataat acaagttgct tggtgggaag
    39061 aatctgaacc aatgagcagt ctaattgaaa taactaataa tgtaaataat ggagaaacca
    39121 ttacaacagc agctgaaact gattatattt atgaaaatcc atataatgat ataacaggga
    39181 gaggaatttt attagcagtt atagattctg ggatagatta tttgcatcct gattttataa
    39241 atgatgatgg aactagtaaa gttttatatt tatgggacca agaagcaaat acaaatccac
    39301 ctccagaagg ttttattttt ggaagtgaat ttacaagaag tgagttaaat atagccataa
    39361 atagaaatga tgggagtttg agtcaagata atataggtac tggaacttta gtttctggta
    39421 tattagttgg aaatggaagg ataaattctc agtacagagg tattactaca gaatcagact
    39481 taatagtagt taaattaaaa tcatatacag atacttatta tgctggaagg ataaattaca
    39541 gtgtttcaga ttttttagca gctataacgt atgttactaa catagcaaga acagaaaata
    39601 aaccactgat aataaatttg actattggag ttaagtcaag tgctgtagca actacttcaa
    39661 tactagatac ttttaatata ttgagtagtg ctggtgtggt agtagtgagt ggtgcaggaa
    39721 atcaagggaa tacagatatt cattattctg gcagatttag cagtgtggga gaagttcaag
    39781 atgtaataat acaagatgga gatgactatg ctcttgatat aacactaaat acgaatggtc
    39841 cagataaagt gggagcacag ataatatctc cttcaggtga agttagtcat gatataaggt
    39901 attctccaga cttttatata tatagaggaa aatttaactt agaaaatact acttatgcaa
    39961 tgagatttat ttatccatat attacctctg gaaaagaaaa tttggagata agattaagag
    40021 atataaaacc tggagtatgg attttaagat tgacttcaga acttataata aatggagaat
    40081 atgacatata cttgccaaat aaaaatttga tagctccaga cacaaggttt ttagaccctg
    40141 attcagtagc tactataact atgtatgctg ctagtgatga tgtaattaca gttggtacat
    40201 ttaacaataa gactgatagt atgtggattg gttcttcgaa aggaccaatt agaggaagag
    40261 gaattaagcc agatatagta gcttcaggtg tagatataat atccacatat aaaaatggaa
    40321 catataatac aggaacagga acaggagtga gcagttctat agtcacaggt gttttagcct
    40381 tattgatgga atacttagaa aaacaggata atgtaccgag attatcattg tttacacaag
    40441 ttttaaaaac atatttaata ttgggtgcta caaaacttga gatatataca tatccaaatg
    40501 tatcgcaggg atatgggatt ttaaatttaa aaaatacgat tcaacagata gcaaatactc
    40561 tatagataag aacctatgta aaattataat tgattattag tttaattgta tcaaatactt
    40621 tagatagagt agaaaaatag cataaaaaat aaatatgaaa attaaaaaac agttttatat
    40681 tttgaataca caaagtaaat attttgtata taaataggta taaattaagt attgaaaaga
    40741 tatgatgtta atttaaaaat aattataatt tagacttatg aattttattt gtaaaattgc
    40801 taaaactatt acaaaataaa taatagaggt gatagttttg gaaagtaaaa aggcaagagc
    40861 attaaaaggt aaagataata aaagacttaa aagttcactt ttagttggaa atgagtcgac
    40921 agcagcatgg gctgatgttg aaaaattaaa acctcatagt aaagtttcaa taccttcaat
    40981 taagggtgtc gaagaagcaa aagactgggt tgacaatgga agtaaattat aaaattttgg
    41041 aaattgaagt aataaagaag taatgaagat aagtatttat tatcattatg taaggtagaa
    41101 ttattatatt ttaaataaca atcagtatca attatataaa tttattgact aaaaatttat
    41161 aaattggtat aattttgtta attagcagaa ataataaaag ataaatactg tgaagagaag
    41221 agtagatata aaatgtagtt ctagcgagtt gaggatggtg aaagctcaat acgaggttta
    41281 tattgaagaa catcttggag tttctaatcg aaagcttatt tagtaagtag acttagacgg
    41341 aaggcaccgt tataggcttt aagcattgct taactaagag gtcattatga caactagggt
    41401 ggtaccgcga gagtaatagt ctttcgtccc tttatatagg gatgaagggc tttttttatt
    41461 gaaattatat ttaaaagaaa ttaataacaa ttatactagg aggatttaaa atgcaaaagg
    41521 aatttataac agtaaaagaa ttgtacagag aaaaagaaca gtacataggg aagactgtaa
    41581 aagtagctgg atggataaga acatctagag tatctaaaaa ttttggattt atagagctaa
    41641 atgatggaag cttctttaaa aatatgcaga tagtatttga tgagaaagta gaaaatttta
    41701 aagaggtagg aaaattagca ataagctcat ctatacttgt agagggagag ttagtatcta
    41761 cagaaggggc taaacaacca gtcgaaatac atgcaaaaag catagttgta gaaggggaat
    41821 cagatagttc gtatccacta caaaagaaga gacatacgct tgaatattta agaacgatag
    41881 cacatttaag accaagaagt aatacttttt cagctgtatt tagagtaaga tcaatagctg
    41941 cctatgcaat acacaaattc ttccaagaaa gaaactttgt atatgcacat tctccaatca
    42001 taacaggtag tgactgtgaa ggtgcaggag agatgtttag aataacaact atggatttaa
    42061 atgatattcc aaaaactgaa gatggcaaaa tagactatac tcaagatttc tttggaaaag
    42121 aggctaattt aacagttagt ggtcaattaa atgccgagat aatggcactt tcttttagaa
    42181 acgtttatac ttttggacct acatttagag ctgaaaactc ttatacagga agacatgctt
    42241 cagaattttg gatgatagag ccagaaatag tttttgcaga ccttgaagat aacatggaac
    42301 ttgcagaaga tatgataaaa tatgttataa gctatgtatt agaaaatgct cctgaagaaa
    42361 tggaattttt taatagtttt atagataaag gattgttaga aagattaaat aagatagtaa
    42421 actctgagtt tattagaata acgtatacta aagcagtgga attattaatt gaatctgggc
    42481 atgaatttga gtatcctgtt gagtggggat gtgaccttca aacagagcat gaaagatata
    42541 taacggagca aatatataat tgtccagtgt ttgttacaga ttatccaaaa gatataaaag
    42601 ctttctatat gagaatgaat gaagatggta aaactgttag agcaatggat ttactagttc
    42661 ctggagttgg agaaatcgta ggaggttctc aaagagaaga aagagaagat gtattgttag
    42721 atagaattaa tgaaatggga ttaagagaag aagattattg gtggtattta gaacttagaa
    42781 agtttggtac tgctactcac tctggatttg gtcttggatt tgaaagaata attatgtata
    42841 tgacaggtat gtctaacata agagacgtta tacctttccc aagaactcct aaaaatgctg
    42901 aattttaata attatatata ataaaactta tataacttta agtataaaca ctaaaatgac
    42961 ttgcatattt atctatttta gagatatgca agttattttt attgtactat aaatatataa
    43021 tttgattact tttattttgc gatataatac ttataggttt atgtaatagt atgtaacctt
    43081 ttaataaaat gcaacacaat tacgtccttg ttcttttgca gtatataggg ccttatcaca
    43141 attacttata aactcattta atgttattgt ctttccaatt ttctttgtat aaactccaat
    43201 actaacagtt acacatttta aaggaacatc atcacgctca aaattgcagg actctataat
    43261 ttttcgtaaa cattctgatt taagtttagc atctgcctca ttacagttaa aaatacatat
    43321 aaaaaattcc tcaccaccat atcgtatagc atgttcattt tcagaacttg taaaatctaa
    43381 aattactttg gcaatatttt gtagacaata gtctcccttt tgatgtccat aattatcatt
    43441 aaattgttta aaataatcta tatctatcat cattccagtt ataggttctt gatttgcatg
    43501 gctgattaat tttttttgta gaatatcttc aaggtatcta cggttgttca ttttagtaag
    43561 gtcatctgtc ataactttgt cgttaagtaa attatttata tgagatattt cttcatattg
    43621 ttgactaatt aaaagtttat catagtaagt aaatacacga tttctatata gcattgtaga
    43681 aacaaaaatg gcaagggatg ttataaaaaa tgtgttgaca atattactaa actcattgcc
    43741 tggtatagtt tgaatcccag gtaagaataa attaagaaac aaaaagcatc ctccaaaaac
    43801 tattactgat tctccaaatt ttaatactga gaaagctgca gctgctaaca taatataact
    43861 aaatacactt aggtcatttc cacctaactg gtcaagtaga gtaattacac aaccccatag
    43921 gcagaaaaaa gtcacataaa ttatccataa atttatataa aacgtacagc aatccttttt
    43981 tttattccaa aggtaagaaa atacaaacat aaagacagaa gatacacaaa atagtgttac
    44041 atacatataa aaataccatt ggcgtcttgg tgtgacaaaa gggcctcctt ctctagctga
    44101 gattgatatc atcataatta tttgagatat tactattatt atgcaaatga ttttacccgt
    44161 atgataaaga taattgcaga gttctttctc aacattgtct ttgtgttttt tgtctagagg
    44221 aaatccaaaa aattttttta ttttttctaa gttcatataa gcctccatta aaaataaagc
    44281 ataaaaataa gtattccttt ctatcattag atatttggaa tacttcgttt atgatttaat
    44341 tatatcaaaa tatattgtgt gtaacaatct aaaattgtga tagataaaat ttattagata
    44401 atgtcgagta actttattga ttaatacttt attataatta agatttacag atagtttact
    44461 actgaaaata aagaatagaa taaatttaaa ttaagcataa taaaatataa ataataaagt
    44521 tcgcattaac aaactattta aatatcaaga actgttaaaa aacaacagca ataaacaaat
    44581 aaaatagata aatatatcca attaaggtat aattaagttt tatatgatat agttatattt
    44641 gataatttac aatagtaaaa cttggaggga aaaaatgggt gaaaagaaaa taaataatat
    44701 gaattattca cataataatt attccaaaaa gacaggtgaa ccaactagaa aaataaaaaa
    44761 tagccatatc actcttaaaa gtaaagaaga aaaaatttgt tctagttgca ataaagaaaa
    44821 taatactaag gataattact gtaaattttg tggaaatgaa ctttatgaaa tagcatcatt
    44881 aagaccactt gaaacaaaac tagacttgaa atctaaaata aaagagcttt catatcatgc
    44941 aaataaaaga ggtgtatttt taacaacatt tacaaccata tttatattgt ttattattgc
    45001 attgatattt aaagctatta taactattca atttaatgat attagttatt tagtaaatcc
    45061 agcacatata atcctagctc tcaacttggg tcaaattagt gtatctatgt ctaccatgat
    45121 gggttctggg tttataaatg ccaatatagg tttgttgata ttacttataa tccctatttt
    45181 ggtattatta atatcaaacc taatttttat gagaaaaaga tgtagagatt caaaaactgt
    45241 attagcaaat tctctaggag ttggaatttt ttatggatta gttttagcta ttttatctat
    45301 ttttactaat gtaaaaacta gttcacatag tatgttagaa tatggatatg cattagaata
    45361 tagttatgaa ttttttagtg ttcttttaaa tggattcgta ttagggttta tatgtacata
    45421 cataactact tataaaaaaa gttatgaaaa agaaaatatg tatttatctc ttttttcaaa
    45481 ttctataaga acattcatat taggttatgt tttagtatta gtaatactat tggtactaac
    45541 tatatctgat agtagttact taaatgaact agatatgagt agttattcaa atggattaaa
    45601 tttatttact atactcccac aaatagctag ttatatgtgg gcttttgcaa atggaatttc
    45661 agtaaccata ataaactcaa cagtatcaat gtttacttta agttcttcat ctttatttgg
    45721 agatactaaa ttaatgtttt atgcaatggg agcattgtct atgttaatat tattattaaa
    45781 tggatacaag ctaagattta agtataatac agatagtata agacctataa tagtatttag
    45841 tatatattat gcatttttga tgggaatatt ggctttattt agtacattta tactagatag
    45901 taatattaat ttctttaata caactaatta tggaacaact ttaataatgc aatttaaagt
    45961 cttacaagct attgtgattt catttgtata tagttttgtg atatctttaa taggatataa
    46021 gctaaattca gctgattaaa tatgattgga gggaatttct gtggaaggaa atactaataa
    46081 taaagtagat gataaatttt ctaaggttaa gaaaaagttt ggtagtggaa aatttaaagt
    46141 tgaattatat aaagaaaaat caaaattaaa tagagagatt gatgatattc aagaagagaa
    46201 agcaaagata ttcttggaaa tgggaatact gacatatcaa aaaattagag aagattctat
    46261 taatgataat agttttgata aattatgtga tgagttacta gaacttgata agttaattta
    46321 tgaaaaaaat atggaaatta atgaaatgga aatggcagaa agtaatgtaa cttgtgagtg
    46381 tggttatgtt ggaaatgtaa atgataaata ttgtgctgaa tgtggtaaaa aatttgaatt
    46441 ggaaaatgaa tgtgatgatt ttataatttg tggttattgt gaaagtgaga tagatacaga
    46501 ggctgaattt tgtccatgct gtggaagaaa aattataata gatttagaat aatattggga
    46561 aacctatgta tagtatacat gggttttttt attgaaatta tttaaatgga cttataacag
    46621 tagttatata aaatgaaaat aaacaccgaa aaaatgaaat aaaatttctt ttaaatgtaa
    46681 aaaacaagct aatatataaa ataaatcagt aaaaatatag atgtgagaaa aaaatatgaa
    46741 aaaatattgc aaagaaaaag ttttcatgtt attattaata cataaatcaa gaaaataaat
    46801 ttcagaaacg aggtaattta aaaaatgcta gataaggtaa agggaagatt aatagtatca
    46861 tgccaagctt tagaagatga acctcttcat agtcctttta taatggggag aatggctaag
    46921 gctgctatgg aaggtggagc tgttggaatt agagctcaag gagttgaaga tattattgaa
    46981 ataaaaaaag ttactggact tcctgttata ggtattataa agagaaacta tgaagattca
    47041 gatatatata taacgccaac taaaaaagaa gttgatgaac ttttaacaac agggtgtgaa
    47101 atgatagcat tagatgctac caatagagtt agaccaaata atgaagactt aaaagaactt
    47161 ataaagtata taaaagaaaa cggtgttcta gtaatggcag atatttcaaa ttatgatgag
    47221 gctatcaaag cacaagagta cggtgtagat tgcgtttcaa ctacactatc tggatatact
    47281 ccatatacta aaacattaga aggtccagat tttgtattaa tggaaagatt agttaaagat
    47341 ttagaaatac ctgtaatagc tgaaggaaag gtaaatactc ctcaagattt aaaaaaggtc
    47401 tttgagttgg gtgttcattc atcagtagta ggttcagcaa taacaagacc acaattaata
    47461 acagaaaaat ttgttaaagc aattgaaatt aattaaaaat taatttataa attaaaaaat
    47521 tattatattt aactatattt gaaaattaaa attggaggta aagatatgag aacaacagat
    47581 atgaagggaa tttattcagc attattagtt tcatttgata aggaaggaaa tataaatgaa
    47641 aaagggttaa gacaaataat tagacacaat atagatgttt gtaaagtaga tggtctttat
    47701 gtaggaggaa gtacagggga aaacttcatg ctttcaactg atgaaaagaa aagaatattt
    47761 gaaatagcta aagatgaagt gaaagaagaa ataaaattaa tagctcaagt tggttcagtt
    47821 aatttaaaag aagctgtaga acttgctaaa tttacaactg atttaggata tgatgcaata
    47881 agtgctgtta caccttttta ctataaattt gattttgaag aaataaaaca ctattataat
    47941 acaataataa attctgtaga taatagatta ataatatact ctataccatt tttaactggt
    48001 gttgatatga gtttagacca gtttggagaa ttatttgaaa atgaaaaaat aataggtgtt
    48061 aagtttacag cagcagattt ctacttatta gagagaatga gaaaaacatt cccaaataaa
    48121 ttaatatttg caggatttga tgaaatgatg ttaccagcta cagttttagg tgtagatggg
    48181 gcaattggtt ctacattcaa tgtaaacggt gtcagagcta gacaaatatt cgaattaact
    48241 aagaatgaaa aaatatcaga agcacttgaa gtacaacatg tgactaatga tttaataaca
    48301 gatatattag gaaatggctt atatcaaaca attaaattac tacttgaaga acaaggtgtt
    48361 gaggctggat actgtagaca acctatgaaa gaagcaactg atgaaatgaa atcaagagca
    48421 aaagaaatat acagaaagta tttttaataa aatactttta gtatgggagg attagtcgaa
    48481 tggtaggatt tacttggata gattttgcaa tactagtggt ttacttattg gcagttttat
    48541 ttgcaggatt gttattttca aaaaaggaaa tgaagggaaa agagttcttc aaaggtgatg
    48601 gaactattcc gtggtgggtt acatcagtat caatatttgc cacattatta agtccaatat
    48661 catttttatc attagcagga aattcttatg gtggtacttg gattttgtgg tttgcacaat
    48721 taggtatgtt tatagcaata cctttgacaa taaaattttt cttacctcta tatagtaggt
    48781 tagaaataga tacagcatat gaatacttag aaatgagata cgaaagtaaa ggtcttagag
    48841 tacttggagc tttgatgttt ataatatatc aaataggacg tatgtctatt ataatgtatc
    48901 ttccatcaat agttctggct ggtcttacag gaatacctgt aaatgtactg ataatagtta
    48961 tgggtgtaat agcaataatt tactcatata caggtggatt aaaggctgtc ttgtggaccg
    49021 attttataca aggaatggta ttaatagtag gtgttacagg gacattgttc tatttaatag
    49081 caagtataaa tggtggtttt ggaacagtaa tggatactct tacaactgga cacaagttct
    49141 tagcaagtaa tgaagttatg tttgataaaa atatactatc tacaagtgca tttataatat
    49201 ttgttggagc tggtcttaat actttttcat catatgtatc gagtcaagat atagttcaaa
    49261 ggtttactac aacaactgat ataaagcaac ttaataaaat gacatatgga aatggtgttt
    49321 tatcaatggg acttgcaaca gtattttatc taattggaac ttgtttattt atatactata
    49381 ctcaaaaccc agatttagct caaacagttc aacaagacca agtatttgca tcatatatag
    49441 cttatgaatt accagtgggt ataacaggaa tactacttgc agcgatatat gcagcttctc
    49501 aatcaacttt atcgacaggg cttaattcag ttgctacaag ttggacttta gatatacaaa
    49561 ctatcataac aaaagatata agtatggaaa agcaaactaa gatagcacaa tatatatcat
    49621 taggtgtagg tatactttct atagctgttg caatagtatt agcaaatgga gaaataaagt
    49681 cagcatatga atggtttaat agttttatgg ggctagtact aggtgtttta gcaggaatat
    49741 ttgtacttgg tgcattttgt aaaaaagcaa ctaaaatggg agcatatgtt ggattcatag
    49801 tatcagcaat tttagttgtt tatttaaaat accgtatgcc agaagtaact tcttgggcat
    49861 attctctaat aacaatcacg acttctgtag tggtaggtac aatagttagt gcaatagaag
    49921 ctaaagttaa agcaaaagta tctttaccaa aagctgagac tactgtttat tatgaaaaat
    49981 aatatttaaa tgagaaattg tcttatagag tgattagata aataatttag ttactctata
    50041 agattgtata atatactttg tatacaaaag tataaaaata gactttataa ttatataggg
    50101 agatagtgct tatgatattt ggaaatataa atcatagtaa gacatattca acattgcatg
    50161 aagatttact tagatgtttt gaatatgcta aagataattc attaatagat tatgaaaaag
    50221 gtacttatac aatagatggt gatgatattt ttgtgaatat tgtagagtat aaaacttgtg
    50281 aaaaagaaga tagattctgg gaagctcata agaagtatat agatgttcat ttgatgcttg
    50341 atggatgtga acgaatagat ataaatttta tagaaaattt agaacaaaaa atatatgaag
    50401 aaaagggcga tttcttgcct cttgatggta aaaataatgg atacatggaa cttagaaaag
    50461 gtgatttttt agtttgttat ccagaagatg ctcatatgac aggaataaaa gttttagaaa
    50521 aagaaaatat caaaaaagct atttttaagg ttttggttag ataatgataa tttatataac
    50581 cactagggct gaaaatagtg atttaacttt cagcgattag tgagacttcg taaattttag
    50641 ttagattact attttcagcc ttagtttttt atgagaaaat tgaaaataat taaaagctta
    50701 aaattttgta aaggagttaa cttatggaaa atatagatgt attcttatta ataggacaaa
    50761 gcaatgctag aggattggga aatccaaaag agagcatcat tccaaatgaa aattgttttg
    50821 aatatttgag tactgatgaa attataaata tgagatgtga gctagagact tcagaaggtg
    50881 atggtactat agcacctgca ttttcaaatg aatggaataa gcttactgga aataaagttt
    50941 gttttattca caatgcaaaa gatggttcaa gaataaaaaa ctggaatcat gataataact
    51001 ggtttctaaa tgacactata gaaaaattta atacaggctg tactacctta agtaaacatt
    51061 ataatataga aaataaatac gttatttgga ttcaaggtga aagtgatgca aaatatggta
    51121 gtgatgtatt gtactataaa gaaagtctaa aaaaaattgc gtataggctt aaagaagaat
    51181 gtatgattga taaaatgttt gtaagtttaa ctggttattg gcttggagaa gatgaatatt
    51241 ttattagaac aagacgaatt gcagcagcac aggagtcggc ttgtagtgaa tgtgatatat
    51301 tatgtgtagg aagcaaaatt gctatgcagt ttcatgacag aggattaact attgatgatg
    51361 ttcattacac tcaagaaggt cttaatatgt taggagagga cttatgtaaa aatatttata
    51421 agtatcatat aaccaaagaa aaaagtgtat taagtgatac tatagactta tcagaagcaa
    51481 ggaaatatat ctgtgaattg gaaaagataa gtaaaagatt tgtgtaatat aaaattttaa
    51541 atagagttgt taatttataa aaataatttg tatggagata tgttatgaaa aattacgttt
    51601 gtatagatgt tggaggtact tcaataaaat atggttttat tagagaagat ggatttataa
    51661 ttgataaatc aagtcttgat actgaagcaa aggaaaaagg tggagaagga atattagcca
    51721 aaataaaaga tatagtaaaa aaatatatag aggaaaatga aataagtggt atatgtatat
    51781 caactgcagg tatggttgac ccagttgaag gtaaaatact atttgcatta gaagaattaa
    51841 ttccaaacta taagggcatg caattaaaaa aagaagtaga aaaagagttt aatataaaat
    51901 gtgaagttga aaatgatgtt aattgtgctg gacttggtga aatgtggctt ggagcaggta
    51961 gaggtgcaac atcttctata tgtttaacaa taggtactgg aattggtgga tgtattataa
    52021 taaataataa actgataaat gggtttagta atagtgctgg tgaagtagga tatatgaatg
    52081 taaatggaag ttcttttcaa gaattggcat ctactagcag tctaattaaa aaagtagcaa
    52141 aaataaaaaa tttgaatgaa aatgacttaa atggaaaaat aatttttgat ttagcaaaga
    52201 ataatgatga agattgttta aaagaactcg ataatatgat aaaatcatta gcagttggaa
    52261 tcgcaaatat atgttatgta ataaatccag aagtggtaat tttaggtggt gggattatgg
    52321 cacaagaaaa gttcctaaaa ccaaaaatag acaaagcatt aaaggaggtt cttatagaga
    52381 gagtttacaa aaacactaat atagaatttg caaagagaca aaatgatgca ggaatgcttg
    52441 gagcattata taatttttta aacaaaatat aaagaataga agggttttta atgagtattt
    52501 tagaacaatt ggaatcacca acttttaaag tcacaaaatc agataaatta ttaatagctt
    52561 atataaaaga aaatatagat gatgtatttt ataaaccaat atcacaaata gctaaagaga
    52621 gcaatattgg tgaagcaact ataactaggt ttgtaaaaaa aatgaatttt aatggattac
    52681 aggattttaa agttacttta gcacaagaaa tatcaactat caataaaaaa aatattataa
    52741 ataaaaatat acaaaatgat gagccagctt tggatacagc aaaaaaactt ttaagttcaa
    52801 atgtaaccac tttagagaac acagtagaga taatcaatag taaggatgta catgactgcg
    52861 caaggcttat aataaatgca aagaaagttt acttcatagg tattggatat tctggtataa
    52921 tagcacagga ttcaaactat aaatttatga gaataggtct taattgtgta agttttgaca
    52981 gtagtcatac aatgataatg atgtcttcca taatggaaga aggagattta ataattgcaa
    53041 tttcacattc tggtgaaaca gaagagatta taaaaactgt aaagcttgca agagccaata
    53101 atgctaaaat tatatcaatt actgaaaata aaaattctga attaaaggat atttcagatg
    53161 tacacttatc ttatgtatcg ggagaaacag tactggaaac cggttcaata tcttctaaat
    53221 tagcacaatt tttcattatt gatttagtat atacacaggt agtaaaagaa ctttctaatg
    53281 aagctattga aaggaaaatt aaaactacaa atgctataaa attgtttaaa aatgaataaa
    53341 ataagaaatt tgtaatgttt tatagagctc tcttaaaaat ttaggaatgg agagatatta
    53401 catgtctaaa ttaaaagatt ataatattga taaagtaata atttttaata atttaagtac
    53461 taaaacgaag aatcaactta aagaaaaagt taaactaaaa agattacaaa aaaaagaaat
    53521 tttattttat gaaaaagata gcttagacag tgtttatata cttttagaag gaaaggtatc
    53581 tatttttaag ataagtgaaa atggagagag aaaagtaatt ttcatattaa atagtgggga
    53641 agtcataaat gatattacac ttgacgcttc taaaaactct actgttggct gtgaagcatt
    53701 tgaaaattca attgtagctt attatagtat tgaagaattt ttagaaatta tgcaaaatga
    53761 ttttcaactt acaaaggata ttatttctta tatggaaaga agaataagac gtttatatag
    53821 acagttgaaa aattctatat ccataaaagt agataaaaaa cttgcagcaa aattatatag
    53881 gttaagtaga gaatttggag tttgctgtgg agaatggact ttactaaatg taaatattac
    53941 agttacatat ttagctgata tgcttggctg taaaagggag actgtttcca gaatgataaa
    54001 ggtattgcaa aaagaagaac ttattaaaat tgacaataaa ggtttttatg ttaaagaaac
    54061 tgaattatca aggtatttta aaaataatta attatg
//
LOCUS       DAMKNB010000019        53285 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.019, whole genome shotgun sequence.
ACCESSION   DAMKNB010000019 DAMKNB010000000
VERSION     DAMKNB010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 53285)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 53285)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..53285
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.019"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            102..1703
                     /locus_tag="PC494_001303"
     CDS             102..1703
                     /locus_tag="PC494_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp11"
                     /protein_id="HDF3911808.1"
                     /translation="MKMNKKILSLGLAVSLILVNFKSVNASSVVEKIYGKDRYETAAK
                     IADKQTYETVILVNTEKSLADGLSASGLSGATKAPILFTQQNKIPADTNRCLKNIKKA
                     YIIGTEDTISKSVEKELDSKNIEVKRIGGEDRLKTSYLIAKEIATIKKVDKVLLTNAY
                     SGEADAMSVSSVATRDGAPIILTDGKSVPFDVKNIQSYCIGSEEIMSNPLVKNTNSVR
                     IEGTDRFETNKNVIDYFFNSADGFYVSDGYQLVDAIAAAPLTKNSPMVLVNDGSDKTV
                     LEGAKNITSVGEINEKVIQQCINASNSNGQPPTITVGSTEVYKGEKFDTGKLNIVAKD
                     NTGKVLPIEVDGFIDTNRVGTYILTLKATDEWGKSTGKRVEIKVLDDKSHDYNSPEFK
                     KMVSTEMYNLINSYRKEKGKEPLLVSSRLEGMANAWSKYMMDKKVFAHYIDGKNAPQV
                     FSEFGMRSEENIAYIYIDSKNVQTTQDAKDLAKAIFEVWKKSPEYNANMLSNEFYSTG
                     FGLYILSDGQVHATQEFLNGNEGSL"
     gene            1922..3520
                     /locus_tag="PC494_001304"
     CDS             1922..3520
                     /locus_tag="PC494_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding repeat-containing protein"
                     /protein_id="HDF3911809.1"
                     /translation="MKVNKRVLSIGLTISLIMAGAPNINALSSIEKIQGKDRYETSAL
                     IADKQIYDTIILVNTDNSIVDGLSASGLSGVAKAPIMLVQRDKIPTDVEKRLKDVKNA
                     YVIGTEDTIGKSVENQLKNKGIEVKRIGGEDRIKTSYLIAKEISAIKPVNDGDKVFLV
                     NGYTGEADAMSVSSVAARDGVPVILTDGKSIPFKVDGVQCYSLGSEEIMSNELVSKTN
                     SVRIAGKDRFETNKKVIQRFYKGTKKFYVSQGYKLVDAVAGSPLAKDKPIVLVNDGSD
                     KSVLRGADEVTSLGGMDKKVVDQCISSASDKNTMPTITANDVEISVGDKFDNSMLNIV
                     ATDYYGNDLKANIKGNVDINKAGTYVLNISVVDNLGQKSEISVNVKVVVNASTKDSNS
                     YEFKAMVSNEMYDLVNSYRKEKGKKSLRELDSLAGMANAWSKYMEDKKVFAHEIDGKN
                     AAEVFFGFGARSGENIAYLPMNVKSVYTSKDAKEMAESIFDLWKKSSKYNENMLKEEF
                     YSFGFGMHVSSKGEVNATMEFLNS"
     gene            3810..6008
                     /gene="slpA"
                     /locus_tag="PC494_001305"
     CDS             3810..6008
                     /gene="slpA"
                     /locus_tag="PC494_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-layer protein SlpA"
                     /protein_id="HDF3911810.1"
                     /translation="MNKKNLAMAMAAVTVVGSAAPIFADTTVKEEGYTVVQDKYEKLL
                     KELKAKIKDGTITSVGVEFDGKPITTLAPKADGSDKDAIAEQLETLTKNQLKGLGDGK
                     YVDFKITYGAKAEVPAASLSADDIQKYADQINASEKILVEVAAGSEAGIAKFDSVNNK
                     VIAGDAPLKVKDAVKATVTTNGSNKKVLTISAAAGLSGFSYGTLKDTGASLSDVDAIT
                     LDTTNATITEGDTKVLDFDNSFKFNESTKKVGSLVTPNTTNTPADPGTKTTVRVIKAV
                     EKTIDVSSNSTTKAKDLAKQYVFTDVSDTDPESLSYMLKNINDGKVAVKNSDGDYEVT
                     IFPEGKRLNTLSASSAKTILGDKDTPAKIVLKASTTKKLADYIDDLITYNNSYSNVQT
                     VAGSDRIETAIELSRKYYNSTDKNALYGDPVNNVVLVGSQAIVDGLVASPLAAEKDAP
                     LLLSSKDKLDSSTRAEIKRVMDLNSSTGIKNNKEVFIAGGVNSISKDVENELKDMGLK
                     VTRLSGDDRYETSLAIADEIDINDKAYVVGGTGLADAMSIAPVASQIKDGEATPIVVV
                     DGKSDKLSKEAEDFLDDAQVDIIGGENSVSAKMEDYIDDATGKSPERISGADRQATNA
                     EVIKEYFDKDGVSNYFLAKDGSTKEDQLVDALAAAAVAGNYGSKHNEDGDITTDASPA
                     PIILATDNLSAEQHVAVSKTATTNGAKNLVQVGQGIADSVVSKLKDLLDM"
     gene            6254..8596
                     /gene="secA"
                     /locus_tag="PC494_001306"
     CDS             6254..8596
                     /gene="secA"
                     /locus_tag="PC494_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HDF3911811.1"
                     /translation="MSVLDVILDKTDELEIKKLNNIVDKIDALEDKIQILDDEALKNM
                     TNVFKDKLSKGETLDDILPEAFAVVREVSKRILGMRQYRVQLIGGIVLHQGKIAEMRT
                     GEGKTLVGVAPVYLNALTGKGVHVITVNDYLAQRDKELMQPVYEFLGLTVGVIINGQQ
                     PVERKLQYQCDITYGTNNEYGFDYLRDNMVTQKSEKVQRELNFAIVDEVDSILIDEAR
                     TPLIIAGGGDEGTKLYELANAFIKNIRDEDFEMDRKDKTIALTASGLSKAEKFFGIEN
                     ITHIDNIEIFHHVNQSLRAHKLMNIDVEYVVRDNEILIVDEFTGRIMDGRRFTDGLHQ
                     AIEAKEGVKINDESKTMATVTFQNFFRLYSKLSGMTGTAKTEESEFEATYKINVVQIP
                     TNKPVIRADLHDKVFKTERAKYNAVVEEIIRINKTKQPVLVGTVSIEKSEKLSKLLKK
                     KGVKHEVLNAKQHDKEAEIISKAGKLGSVTIATNMAGRGTDISLGAGDKEEEEKVKEL
                     GGLYVIGTERHETRRIDNQLRGRSGRQGDPGTSRFFVSLEDEVIKLYGGKSIEKILKR
                     MNANEDDALESKALNRAIERAQKGIEGKNFEQRKNVLKYDDTINEQRKVIYDERNKVL
                     DGSDIEEEIQKMVMDIITEAAEKYLKKFRDYHGYFKYLYNTFMPADTLLIPDLDKKNV
                     EEIVNQTYQISKRVYDLKKMMIGIEELAQLEKRVLLQVVDTYWVDHIDAMDQLRQYIG
                     LKSYAQKDPFKEYAIEGYEMFEALNRNIRITTVQYLYKFN"
     gene            9010..10881
                     /locus_tag="PC494_001307"
     CDS             9010..10881
                     /locus_tag="PC494_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding repeat-containing protein"
                     /protein_id="HDF3911812.1"
                     /translation="MNRKNLYVIMAAAMVSTSVAPSFAAEATQVKKQTITKKEATELV
                     SKVRELMAQRYTGGSQVGQPIYEIKVGETSSQLKIITNIDELEKLVNALGENKELLVT
                     IADKGHTTNSANEVVAEAIEKYENSADLSAEANSITEKAKTEATGIYGVATVEASYDS
                     TKDKLVITLKDKTDVVTSKTLQIGIGDEKVDLTANPVDIAGTNLDPSAEGFRVSKINK
                     LGVEGAKNIADIQLAEITIKNSDLNTVSPQDLYDGYRLTIRGNTIANSVGKSISDISS
                     KDSETGKYKFTVKYTDTSGKAIELTVESTNDKELKDVKDALNGNTKVNLIAGEDRYAT
                     AVAIAKETEYTDNIVIVNSNKLVDGLAATPLAQSKKAPILLASDNEIPKVTLDYIKEI
                     IKKSPSAKIYIVGGESAVSNTARKQLESVTKNVERLAGDDRHTTSVAVAKAMGSFKEA
                     FVVGAKGEADAMSIAAKAAELKAPIIVNGWNDLTADAIKLMDGKEIGIVGGSNNVPSQ
                     IENQLADIDKDRKVQRVEGETRHDTNAKVIETYYGKLDKLYIAKDGYGNNGMLVDALA
                     AGPLAAGKGPILLAKNDITNSQKNTLDKKLNLGAEVTQIGNGVELTVVQKIGKILGW"
     gene            10990..11697
                     /locus_tag="PC494_001308"
     CDS             10990..11697
                     /locus_tag="PC494_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIG-L family deacetylase"
                     /protein_id="HDF3911813.1"
                     /translation="MIEATLFFSPHQDDETLSMGSAIIEHVERSDTHVILCTDGSKSI
                     IRKVLDDGGSCSYHIKDVHKYSLSESDFSKNRDEEFKNSCKAMGVKENNIHIENNRAH
                     DGELSKEKARDIMLKYLEKYPDAKVKTVTPYKALGIHEDHRALGEAALELYREGKIKD
                     LRFYVEPYDYNDFKKVNPNVRVWKVLSSQEEKLLNAMDAYKKWNPENGNYAIGYHSVK
                     SHFDELKSNKIQYVHAP"
     gene            11730..13862
                     /locus_tag="PC494_001309"
     CDS             11730..13862
                     /locus_tag="PC494_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding repeat-containing protein"
                     /protein_id="HDF3911814.1"
                     /translation="MKISKRIMSLLTATFFIFALSINIADASSKESLVGSGRWETAIK
                     ISQNGWKDATNAILVNDNSIADALSATPFAKLKDAPILLTQSDKLDSRTKAELKRLGV
                     KNVYLIGGMNTLSTNIEKQLKSENMTFERISGNSRYETSLKLAERLDKEKSISDIVVV
                     NGEKGLADAVSVGSAAAQENMPIILSDPNNGIKVANSFISSKNIKKSYIIGGTYSVSS
                     SIEQSLPNVKRLSGNNRNETNAKVLEEFYKNTDLKNAYITKDGMKKQGDLIDSLAVGV
                     LAAKNSSPVVLVGNSLDSSQYDVLNTKSFDNIVQVGGNGNEDAVKDILDLQEETIYRV
                     KTADELDVALRKADANDIITFKPDDNKKITSSFSIETKKAITVELEGLYTQTITVNMP
                     NGELTNKGTLDGTVKIMDIKNGTFINEGDINDIDIYDPNGCKIENKSGGDIWVLTISS
                     SAKDVNIENKGDISKVTNNSTSVIIRNSGNIDTLSGINAPAISGNKPRVDDTDKDEKR
                     ASGIYPTSEPLSPARAGYISVKIFTKPEDTNYKIYYRVVSSRPSALYIGDRIDTSDWT
                     AVPSSVLPFTIKAENGYYIEAVEINSDTKKVSRWGKSDYIDDGFYLKSETAKGLSADI
                     DFDGDYVKLTATGADSGCTVYYRIVSKKPVSMNVGDKVTISDWDEITTNRVRIEANDV
                     KDKYIELVELDDSTNKVTRWGASDKVVE"
     gene            complement(13915..14310)
                     /locus_tag="PC494_001310"
     CDS             complement(13915..14310)
                     /locus_tag="PC494_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HDF3911815.1"
                     /translation="MILKKHRETILYLFFGAFTTLVNIVSYLFFTRVILFNFMVANAL
                     AWILAVLFAYVTNKFFVFESKRIELIFLFKEFLFFVSFRLLSGIIEMIIMYIMIDLFF
                     VNDITVKVFTNIIVIVLNYLFSKMIIFRK"
     gene            14537..16948
                     /locus_tag="PC494_001311"
     CDS             14537..16948
                     /locus_tag="PC494_001311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding cysteine protease Cwp84"
                     /protein_id="HDF3911816.1"
                     /translation="MRKYKSKNLSKLLALLTVCFLIVSTIPVSAENHKTLDGVETAEY
                     SESYLQYLEDVKNGDTAKYNGVIPFPHEMEGTTLRNKGRSSLPSAYKSSVAYNPMNLG
                     LTTPAKNQGSLNTCWSFSGMSTLEAYLKLKGYGTYDLSEEHLRWWATGGKYGWNLDDM
                     SGSSNVTAIGYLTAWAGPKLEKDIPYNLKSEAQGATKPSNMDTAPTQFNVTDVVRLNK
                     DKETVKNAIMQYGSVTSGYAHYSTYFNKDETAYNCTNKRAPLNHAVAIVGWDDNYSKD
                     NFASDVKPESNGAWLVKSSWGEFNSMKGFFWISYEDKTLLTDTDNYAMKSVSKPDSDK
                     KMYQLEYAGLSKIMSNKVTAANVFDFSRDSEKLDSVMFETDSVGAKYEVYYAPVVNGV
                     PQNNSMTKLASGTVSYSGYINVPTNSYSLPKGKGAIVVVIDNTANPNREKSTLAYETN
                     IDAYYLYEAKANLGESYILQNNKFEDINTYSEFSPCNFVIKAITKTSSGQATSGESLT
                     GADRYETAVKVSQKGWTSSQNAVLVNGDAIVDALTATPFTAAIDSPILLTGKDNLDSK
                     TKAELQRLGTKKVYLIGGENSLSKNVQTQLSNMGISVERISGSDRYKTSISLAQKLNS
                     IKSVSQVAVANGVNGLADAISVGAAAADNNMPIILTNEKSELQGADEFLNSSKITKSY
                     IIGGTATLSSNLESKLSNPTRLAGSNRNETNAKIIDKFYPSSDLKYAFVVKDGSKSQG
                     DLIDGLAVGALGAKTDSPVVLVGNKLDESQKNVLKSKKIETPIRVGGNGNENAFNELN
                     TLLGK"
     gene            17245..18822
                     /locus_tag="PC494_001312"
     CDS             17245..18822
                     /locus_tag="PC494_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp5"
                     /protein_id="HDF3911817.1"
                     /translation="MKAPKTILTILTIALTLSSISIIPSYALTEEKLIGNGRYETAVK
                     ISQKAYSSSPNVVLVNDNSLADALSATPFAKAKGAPILLTESDKLDDRTEKEIKRLGA
                     KDIYLIGGTAVLNKDIENKLKSNGLNVERINGKDRYETSLILANKLKDIKDIKEVAVV
                     NGEKGLSDAVSVGAPAAQNKMPIILSSPKDGVEAFDKFIRDEKVIKAYVIGGTNSVSR
                     AVEKSLPNAERVSGKDRNETNAKVIEKFYTDTNLSNLYVTKDGSKNENQLIDSLAVGV
                     LAAKNESPVVLVGNKLNTKQRDILSTKKLNTITQVGGNGNEEAFDEIKSLQEKTVFEA
                     KTVEELTDMINIASPNDIINFKPKENTVNEAFRMVTNKPITVNIKGDCSKTLTVDMPN
                     GEVNNYATLVNVIVRNIGEGGFNNHDTITILSVRDKNGRVIENTRNSDIDTLMILASA
                     NDTKLINDGYIGKLIDNSSNSDITNNGTIDKKVNQVEDLEAKVDSIEKAIDSISQKVN
                     KIQDILDKLGFLKKFLS"
     gene            18956..20263
                     /locus_tag="PC494_001313"
     CDS             18956..20263
                     /locus_tag="PC494_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5009 domain-containing protein"
                     /protein_id="HDF3911818.1"
                     /translation="MGIGIECNKKINKSIDKTRIKKNNLNSNSNSNSNSNSNSNSNSN
                     SNSNSNSNSNKISNNAVDSKLMNSRIKSIDIIRGLSIALMIVCNNPGTWMRMYPQLRH
                     AVWHGVTLADFAFPFFVISLGVTIPISINSKLKNNKSTLSIILSIFKRSILLILFGFF
                     LNYLGNPDLDTVRILGVLQRMGLVYFVTSLAYLLLKKLNVGSTATIITFLYIATFIIV
                     GYYILAKPYGFELEGSLAQLVDLHFFKGHLYKPEFEPDGFLTSIVAISSGMLGCTMGC
                     VLLKENLGEYKKFFKILVMSIILLIGAFIFNQYFPFNKRLWSSSFVLLMAGSYGILLS
                     IFYFICDIKNKSKIFTPIIALGSSPIFTYMCLEILSHVFWNVPKLTNKVDYPTTLVEW
                     TTYELITPWAGTTWDSLIFSLLYVLFWVIVMSIMYKKKIFIKI"
     gene            20517..22541
                     /locus_tag="PC494_001314"
     CDS             20517..22541
                     /locus_tag="PC494_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HDF3911819.1"
                     /translation="MKKTTKLLATGMLSVAMVAPNVALAAENTTANTESNSDININLQ
                     RKSVVLGSKSNASVKFKEKLNADSITLNFMCYDMPLEATLNYNEKTDSYEGVINYNKD
                     PEYLNVWELQSIKINGKDEQKVLNKEDLESMGLNLKDYDVTQEFIISDANSTKAVNEY
                     MRKTSAPVKKLAGATRFETAVEISKQGWKDGSSKVVIVNGELAADGITATPLASTYDA
                     PILLANKDDIPESTKAELKRLNPSDVIIIGDDGSVSQKAVSQIKSAVNVNVTRIGGVD
                     RHETSLLIAKEIDKYHDVNKIYIANGYAGEYDALNISSKAGEDQQPIILANKDSVPQG
                     TYNWLSSQGLEEAYYIGGSQSLSSKIIDQISKIAKNGTSKNRVSGADRHETNANVIKT
                     FYPDKELSAMLVAKSDIIVDSITAGPLAAKLKAPILITPKTYVSAYHNTNLSEKTAET
                     VYQIGDGMKDSVINSIASSLSKHNAPTEPDNSGSAAGKTVVIDPGHGGSDSGATSGLN
                     GGAQEKKYTLNTALATTEYLRSKGINVVMTRDTDKTMALGERTALSNTIKPDLFTSIH
                     YNASNGAGNGVEIYYKVKDKNGGTTKTAASNILKRILEKFNMKNRGIKTRTLDNGKDY
                     LYVLRNNNYPAILVECAFIDNKSDMDKLNTAEKVKTMGTQIGIGIEDTVK"
     gene            22761..23447
                     /locus_tag="PC494_001315"
     CDS             22761..23447
                     /locus_tag="PC494_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HDF3911820.1"
                     /translation="MSGYTNDECEIPKIKSYPGADKEIASEIDYSIVKGTVLFDLYQR
                     IMDLVLSIIGLVIGLPLIAIFGILIKIEDKGPITYKQERLGKCGRRFYIYKLRSMRTD
                     AEKFGAQWAEKDDPRITKVGKFIRKTRIDEIPQLFNILKGDMGLIGPRPERPNFTVQF
                     NEEIPGFINRLAIKPGLTGWAQVNGGYEITPEEKLKEDIYYIKNRSILLDFKILFKTV
                     KVVLTGDGAR"
     gene            23542..24597
                     /locus_tag="PC494_001316"
     CDS             23542..24597
                     /locus_tag="PC494_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp7"
                     /protein_id="HDF3911821.1"
                     /translation="MIKKISTILSLVLLISISSTIGVFADANPKRELIEGSIPEISTE
                     LNKRAFKDSKEVILVNEESIVDSISATPLAYAKNAPIVVTKSKNLGRVTRNYLKELGP
                     EKVTIVGGLKAVSKDAERNIEKMGMKVERIRGKDRYDTSLKIAREMYRTVGFDEAFLL
                     SSTTGLENAISVYSYAAKSGMPIIWAKDEGFEEQIDFLKGKNLKKIYALGDSKEFIAE
                     IDSNLKNIEGIKQINKSSTNVDLIKKFYDEKDIKKIYTARLDFGSRSDVNEYISLGVV
                     SAKENMPILICSDNLSRAQDKFLKDSNINDVVEVGYTVGDYSLFKSIFNLTFLSCIVL
                     ILLLLLITFRALRYESK"
     gene            24712..26268
                     /gene="murJ"
                     /locus_tag="PC494_001317"
     CDS             24712..26268
                     /gene="murJ"
                     /locus_tag="PC494_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="murein biosynthesis integral membrane protein
                     MurJ"
                     /protein_id="HDF3911822.1"
                     /translation="MSKTAKAALWIMAATMFSKVLGFLRELVLANFYGTGMYADVFVL
                     TLNIPGLIIAVIGSAVATTYIPMYFETKKRLGDEGALKFTNNVLNICYIMAIVIAIIG
                     LLFTEQFVTVFAAGFRNDPAKFQAAILFTKIMISGVLFLSGSKIFSSFLQVNDSFVIP
                     GLIGIPYNIIIIAAIALSAGKNVWILPAGALLAMASQLLFQLPFAFKKSYKYKPYINL
                     KDESIKELVNLVLPMLVGVAVGQLNIFVDRLLATTLGDGKLSALNYANRLNEFVMALF
                     VTSIITVIYPKLAKMSGKDNKEGFISTIVKSSNCIILVVLPISIGAIILAEPLVRILF
                     QRGKFDALSTDLTSIALRLYSLGLLACGVRDVLYRAFYSLSDTKTPMINGSIALIINI
                     VLNLILIRPLGHAGIAISTSTSNIITVILLFISLKKKNGYFGGDKIIKTGLKSLVASG
                     VMAVATLLIYNNLYAFMGSGTIKEIISVGAGVLGGASVYTVLIVLFKVEEMDLAFEFL
                     RKGKQKLLRR"
     gene            26314..28020
                     /locus_tag="PC494_001318"
     CDS             26314..28020
                     /locus_tag="PC494_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HDF3911823.1"
                     /translation="MDYKNNYEMWLNSPYFDEQTKNELLSIKDDEKEIQDRFYKNLEF
                     GTGGLRGIIGAGTNRINIYTVRRATLGVLNYIMKTQGEEGKQKGIVIAHDSRYMSREF
                     CIEVAKTLSAYGVKAYIFEELKPTPELSFAVRYLKCAMGIVITASHNPKEYNGYKVYD
                     SDGGQICIDMANDIIAEVNKIDDYSTIKSIDFEEALSKNLITILDNEVDDEFIKAVKK
                     QVLRQNIIDEYGKKLKIIYTPIHGTGNKPVRKVLNECGFENVMVVKEQELPDSNFSTV
                     KYPNPEEKSVFNIAIEMAKNNGTDLIIGTDPDCDRVGIVVKDSSGEYVVLNGNQVGSL
                     LVRYILESLVEENKLPKNNPTIIKTIVTSELGAKIAKAYNVDCLNTLTGFKFIGEKIK
                     AFEESNDRSFIMGYEESYGYLIGTHARDKDGVVSSLMICEMAAYYSSKGMNLYEALID
                     TYNKFGYYKEDLKSVTLKGIDGIKKIKEMMLYFRSVKIDNVADVKVDKILDYKDGVDD
                     LPKSDVLKFLLEDGSWIAIRPSGTEPKIKFYFGANSDNQEDVEFKLNNLISYILNVVD
                     SI"
     gene            28042..29115
                     /locus_tag="PC494_001319"
     CDS             28042..29115
                     /locus_tag="PC494_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-1-phosphate guanylyltransferase"
                     /protein_id="HDF3911824.1"
                     /translation="MKVYNVIMAGGGGTRFWPLSRQEVPKQLINLSGEDALINETINR
                     IDSLAKKDDLFIVTNEKQLEALKDIVKDKCLDSNILPEPCARNTAAAIGFAAFNIMKK
                     YGDGVMCVYPADHYIKDEKEFKSILEKAIYIAENNDKLVTIGITPTFPSTGYGYINFN
                     RENTIEDVAYEVVEFVEKPNYEIAKEYVNSKKYVWNSGMFVWKVSKILEDFKRYLPKV
                     YEKLEDISKYLGTKEEMEKIKEIYPTIQSISIDYGIMERSNDVIVVPGDFGWNDVGSW
                     DSLGAIYPTDDEGNIKRGENITIDTKNSIIYSDDKLISTIGISDLIVVSTNDAVMVCR
                     KDKAQDVKKIVEQLKEEDRQEYM"
     gene            29127..29849
                     /locus_tag="PC494_001320"
     CDS             29127..29849
                     /locus_tag="PC494_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HDF3911825.1"
                     /translation="MIPKKIHYVWFGGPKGNIENICINSWKEKLPEYEIVEWNEKNFD
                     IEKEIKGNKFLEECYKRKLWAFISDYTRIKVLYEQGGVYMDTDMQILKDITPLLENNR
                     LVCGYEDDREYINGAIIGVEKGHPFLKDLLEYYEKEVLTSSLFTIPKIMTHLMEKNYK
                     KIDPNNYEEGIRVYDKEYFYPFGFKEDFTPECITENTFGIHWWGKSWAKKRNYFLESK
                     HLTGVNKIWKCCKIFASNTLRS"
     gene            29865..31022
                     /locus_tag="PC494_001321"
     CDS             29865..31022
                     /locus_tag="PC494_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide polymerase"
                     /protein_id="HDF3911826.1"
                     /translation="MKTLNDDRNIMIRKYLYIFVLFIILLRKYMISFIDPNMDIGMIK
                     SALFYSSIGILMLLFLFDKRKSITEMVLVGVCVLLYLLNREGAILLIVLLAVSAKQID
                     DKFIVKNYLIISACFLMVAILLFNLFPSLIFNQEVHYRYIEKIDMLVTRMDFGLGNPN
                     SVFYHMVTIYAAYIFLRYKDYNKWDRILLFGSAFFVYQTTYSRTGFFTILAGLIFVEI
                     IRWIDIKKIKGLPMLLKTLPVILTLFSVIIGTVFDKSTLLNRLLASRPKFWNVYLAEK
                     GNFLKPFGNSYSPAIKATNPLDSSYVYIISVLGVVACILFMYLMYKGIESFIEKDKKA
                     YLVALFIFLLYSFAENLLLEASFSFAVVLLIKEVILNDKREIDLWKMKSRR"
     gene            31025..31864
                     /locus_tag="PC494_001322"
     CDS             31025..31864
                     /locus_tag="PC494_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HDF3911827.1"
                     /translation="MLISLIMPTLNRYDDIYLLMDSLENQTYKNFELIVVDQNDNSKV
                     KEIVDKYIDKLDIKYIKSSKKGLSYNRNVGIDNAVGQIIGFPDDDCVYENDTLEKVIN
                     FFNKNKDYKIYSCKTMDSNKVDAFKKMYDGTCDITSSNVLDTITSITFFIDFEGKDYT
                     RFDEKLGVGGEFGAGEEIDYVLNLLSLGFKGKYFGNDIIYHPAKKHSKSKEKYQKDYN
                     YGRGFGALCKKEIVYRKNYKFAKVMVSKLVRNIGGLILSSNRDYHSATIKGRINGFRQ
                     YKL"
     gene            31879..33054
                     /locus_tag="PC494_001323"
     CDS             31879..33054
                     /locus_tag="PC494_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-glycerol glycerophosphotransferase family
                     protein"
                     /protein_id="HDF3911828.1"
                     /translation="MDKVKFLINMLLAFFIYPFNKHKFNGRDIWLIGGHSGDIYNDNS
                     KFFYEYMLKEHNDVETYWVVNKDSKVFDKIPGKKLIRGSVENYLYYYNSKAIVFSHAP
                     SADIAPYNFAVPVLNYFHKKTIKVFLNHGTISFKKRKPMNKKFKNIIDNLYKSYNIVT
                     ASSEFERNVMVNDWGMLDDSVYIIGNARYDNLPTNEVAQTRDILYTPTWRDWIKFSSG
                     KFTDTDYFKNIMNFLNDDKLNKILDEKDINVKIYMHHLMHEFIDDIKENITGKRIVFL
                     DKGVTLANEIRKSAANITDYSSVAIDFLYMNRPILFYQFDLDEYMEKVDSYIDLKSEM
                     FGSLAYNNDEAVNKLIDIIENNFEVMDNQKNERNKFFRYNDNKNCKRIYDCVLSKIK"
     gene            33083..33832
                     /locus_tag="PC494_001324"
     CDS             33083..33832
                     /locus_tag="PC494_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HDF3911829.1"
                     /translation="MKKNLVSIITPMYNSEKFIEATIKSVLNQTYQEWEMLIIDDCST
                     DNSPNIVKSYMQQDSRIKCIKTETNKGVSNARNLALSKATGQFIAFLDSDDQWNSSKL
                     EKQVNFMLENDYVISFTSYELMDENDKKLNKVIKVPPNVDYRRLLKGNILGCLTVVID
                     KSKLDFEIRMSGVRHEDYVLWLSILKKGHIAHGINEVLALYRKSSNSLSGNKIKAAMW
                     TWNIYRNIEKIPLYKAIYYFINYGINGIKKS"
     gene            33854..34762
                     /locus_tag="PC494_001325"
     CDS             33854..34762
                     /locus_tag="PC494_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HDF3911830.1"
                     /translation="MYKYKFTVFTPTYNRAHLLENLYNDLKAQTYDFNDFEWLIVDDG
                     SSDSTKELVEKFISENKLNIRYIYKENGGKHTAINLGVKNADGELFFIVDSDDGLIKD
                     SLEIANDEWDSLENKEGFSGVVGLCVYPSGDLIGTEMPEDKKICHFADLYFKYGVKGD
                     KSIVFVTDELIKFPFPERKEVRFLPESVVWNEMSKYYKVICVNKPMIIRDYLDDGLTK
                     NILSKNALRGRALEFLYLINQNTYPLSRYPYMWIKNYINLARYSLLSDSHYFGELRKV
                     SDKLLYLALFPLGYYKYIGQRKLVSK"
     gene            34810..35562
                     /locus_tag="PC494_001326"
     CDS             34810..35562
                     /locus_tag="PC494_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HDF3911831.1"
                     /translation="MNEPLVSIITPVYNSEEFLSETIKSIQNQTYKNWQLLLVDDCSK
                     DNSSEIIKSFRKEDARIKYIKLEKNSGAAVSRNVGIKNAEGRFIAFVDSDDLWDSRKL
                     EIQIEYMLKENVGFSFTSYRYMRQDGSKTNKVARAPKKIDYEGLLRNTIIGCSTVVID
                     KEIVGEFSMPLVRRGQDTATWLQLLKKEKYAYGIQEDLVNYRLVGNSISSNKIKALKR
                     TWNTYRNVENLSLPKSLYVFCFYVFNAIKKRV"
     gene            35516..36883
                     /locus_tag="PC494_001327"
     CDS             35516..36883
                     /locus_tag="PC494_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose/GDP-mannose dehydrogenase family
                     protein"
                     /protein_id="HDF3911832.1"
                     /translation="MYFVSMFLMPLKKEYKFYILGGKKMKIAIAGTGYVGLVTGVCLA
                     EVGNENVVCVDVDEQKVKSMKLGIAPIYEEGLEELMVKNYNRGRIDYTTDYKKAYEDV
                     DVILIAVGTPERSDGSANLDYIKAVAKQIAETVTKDTLVVIKSTVPIGTNEEIEDYIN
                     RNLKNDVKVELASNPEFLSQGTAVKDTLHASRIVIGVESEWAREILEEIYKPFNQPII
                     VTNRNSAEMIKYASNNFLALKISFMNDIANLCEIAGANIEDVALGMSYDDRIGSKFLK
                     AGIGYGGSCFPKDTKALHWLSEHNGYELKTVKAAIEVNESQKLKLVRKASKLVESFQD
                     MKVAVLGLTFKPDTDDIREAPSIPNIKYLLERGARVTVYDPIGVNNTKKIFGDSILYA
                     DSVDDAIEDAEICFIMTEWKDVLNYDIHKYKEKMKNPLVLDGRNCYKIKDMEELGIEY
                     YSIGR"
     gene            36889..37980
                     /locus_tag="PC494_001328"
     CDS             36889..37980
                     /locus_tag="PC494_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HDF3911833.1"
                     /translation="MKTVCYLADGSNPHTLKWCSFFKNKGYDIHVISLNGGHMEGIKI
                     YNFGSNVEELKNENISKKTGYLGSIKQIKKLVNEIKPDILHAQYASSYGFIGSLLGYH
                     PYIISVWGTDIYDFPNNGFIQKQIIKHNFRKADYIFSNSRDMAKEANKYTAKHVDVTF
                     FGVDMDRFKPMEVEKEDAFVIGIIKSLEKKYGIEYLIQAFKMLKDEYKDKKIILKIGG
                     SGSQMDNLINLAKELGIENDVQFLGRISPENVSKTFNSFDVTVFPSLREGFGVAAIES
                     EACEVPVIVTNVGGHPESVWENETGLIVEPKQPEEIKNAIIKLMENDELRLNMGKKGR
                     QFVRENYEVNLNFNDIEKIYDSIFDKYKK"
     gene            38064..39977
                     /locus_tag="PC494_001329"
     CDS             38064..39977
                     /locus_tag="PC494_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HDF3911834.1"
                     /translation="MRESIDLEKESFFNRLFKKYKFRHLTLLILDICSVLVAFRMSLS
                     LTGNLNAFTTNDIIISVCIYIVLHIVSFRLFKCYNTLWRYAGEEEIISIFVATLAYLI
                     PIYIINKLLGFDYPIMFYVLNTIFIIMFTSGARIAYRAIRIVMNKTYSRGKVSNILII
                     GAGDAGEMVIQELKRNPELKKVAVAIIDDDKNKIGRIIHNVKIVGTTSDIKDVVEKYN
                     VDEIIFSIANIEKRRKKDIIDICKNTNCKIKTIPGIYEIIDGKVDIKQIREVEIEDLL
                     GREPIKTNLREISNYIEGKVILITGGGGSIGSELCRQIAGFNPKELIIVDNYENNAYS
                     IQQELLRKYKNKLDLKTVIASIREEKRMDEIFNKYKPEVVFHAAAHKHVPLMESSPGE
                     AIKNNIFGTLNIAGLSSKYRAKKFVLISTDKAVNPTNIMGATKRAAEMIIQTMNAESQ
                     TEFVAVRFGNVLGSNGSVIPLFKKQIEDGGPVTVTHPDIIRYFMTIPEAVGLVIQAGA
                     MAKGGEIFVLDMGEPVRILDLAKNLIKFSGFEPDVDIKIEFSGLRPGEKLYEELLMSE
                     EGLLDTEHKKIFIGRPIDVDREKITKYLKLLREITNNEEVEKIDGIMRELVPTYIKPE
                     DANIKEIATTREK"
     gene            40176..40883
                     /locus_tag="PC494_001330"
     CDS             40176..40883
                     /locus_tag="PC494_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HDF3911835.1"
                     /translation="MMNIKNKKHILKKFIAMVLIAGVVTVEAGAITASAAEPTNSPMS
                     ATVDQCDFLNVRSGASANDAVVGKINTGDKVEVLELHSNGWIKIKSVDNVTGWVNGDY
                     LTIQGGNVDAKVQNVLNLAFKQQGKPYKWGATGPNSFDCSGFTSYVYKNGAGVNLPRV
                     SRSQATVGKKVSRAELKPGDLVFFGSGGSINHVGLYVGDSKFIHSPQTGDVVKVTSMA
                     PGTNYAKRLITATRVLQ"
     gene            41185..43296
                     /locus_tag="PC494_001331"
     CDS             41185..43296
                     /locus_tag="PC494_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding glycosyl-hydrolase Cwp19"
                     /protein_id="HDF3911836.1"
                     /translation="MKKISILVLSLIMTLTMCSVSSFADSSNDKEMRAAWISTVYNLD
                     WPKTKNNEAKQKKEYTDLLDKLKSVGINTAVVQVRPKSDALYKSNINPWSEYLTGTQG
                     KDPGYDPLPFLIEEAHKRGMEFHAWFNPYRITMADESIDKLPANHPAKKNPSWVVKHG
                     NKYYYDPGLPEVRKYIVDSIAEVVQNYDIDGVHFDDYFYPGVSFNDTATYQKYGKGQN
                     KDDWRRENVNTLLRDVKASIKSIKPNVVFGVSPAGIWRNKSSDPTGSDTSGNESYVGT
                     YADTRAWIKQGLIDYVVPQLYWPIGLKAADYSKLVAWWANEVKGTNVDLYIGQGIYKQ
                     GQSSYGGQNIAKEIVQQVTLNRKYSEIKGSMYFSAKDIANSTSIQKDLKSLYSSSEEP
                     VTPPSNVKVEKLRGDERYDTAVAISKKGWATNSDTVVLVNGYSIVDGITSTPLATSND
                     APILLVNKDNIPTSTKNELKRLNPSKVILIGGNNSIGDKVESEIKDTLSNVSINRVGG
                     SDRYSTSLMIAKELVKTNPVEKLYITSGTGEADSLSIASKAGEEKQPIVLVSKDNVSD
                     EVYNWISDLKVKDAYFIGGNLSISDSVINKLDKVITNDVSKNRIAGENREETNGKVIQ
                     KFYPNAEYSSMFVSKSNQLVDALTSGPLAAKLKSPVVMLGNSVTSAQKTALEPKKTTL
                     VYEAGDGINQNTLNTFLNLVK"
     gene            complement(43494..44459)
                     /locus_tag="PC494_001332"
     CDS             complement(43494..44459)
                     /locus_tag="PC494_001332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HDF3911837.1"
                     /translation="MSKLKKFVILLAFLVVIFPISVYGYFYYKLSAIHDSSISSDLLD
                     NNDHKNEDGIINILLMGTDARPNEDSSRSDAMMILTIDNKHNDIKLTSLARDSYVDIP
                     GHGKQKLTHAYAYGQADLLIQTIEENFNIDIQNYACVNFESFMYIIDAIGGVEVTVEK
                     GEIRELNKFIPETYKWNKSDDKGSIQYIRNSGKQTLNGYQALSFARIRHNDTAFARDG
                     RQRQIIQAIIKKTETLPVTKYPGLLDAVLPYVKTNMKPNAILSLGAQVLKMGDLNIKQ
                     FEFPIDDEIHSTGGIYGKAGWVLRFDPDTLDILHDFIFNDIEFKQ"
     gene            complement(44744..45700)
                     /locus_tag="PC494_001333"
     CDS             complement(44744..45700)
                     /locus_tag="PC494_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HDF3911838.1"
                     /translation="MSGLKKFVIFLALLVIAFPVSIYGYVFTKLKTIQDDSINTEALS
                     SNDYKNEENITNILLLGTDARPGEEVSRSDAMMILTIDNKNKSLKLTSLNRDTYVNIP
                     GRGEQKLTHAYVYGQANLLIETIEENFQLDIQNYAVVDFFSFMDIVDALGGVTVTVDK
                     SEIRELNKFIPETYKWNKNDNKGSLKYIRNSGEQKLNGYQTLAFSRIRKNDSTDERDR
                     RQRSVIQSLINGVKDLPVTKYPNLVNTILPYVKTNMNPNEIISLGKELLSIGNLNLKS
                     MEFPLSTENGRKIGNAGYVIPFEEYELDAMHDFIFKDIMVED"
     gene            46068..46856
                     /locus_tag="PC494_001334"
     CDS             46068..46856
                     /locus_tag="PC494_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HDF3911839.1"
                     /translation="MIKLIATDLDGTLLDEKSEINPEFYKVFKKLRERGIMFSAASGR
                     QYQNLIKKFEDIKDDMMFISENGTLVVYKGKEILSNPLNKELVNEIIETTRSIKGKKI
                     VMSGKKYAYIESKDEAFIQEVSTYYAKFKIVEDLTKVEGDILKIAVFDFKGAEHNNNI
                     YFEKFSDRAQVCISGVEWLDLTAKGANKGSAIKKVQKMLDIKYEETMVFGDQLNDVEM
                     MKSAYHSYAMENANEHLKQIARFRAKRNTENGVVDKIKEVIKIG"
     gene            complement(46979..47449)
                     /locus_tag="PC494_001335"
     CDS             complement(46979..47449)
                     /locus_tag="PC494_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4358 domain-containing protein"
                     /protein_id="HDF3911840.1"
                     /translation="MKKILILFFSIILSLGMVSCSSSGDYKNVSTSKIKKALKSSDLL
                     IKESKIFDAKDFNYFNDVEEDIIQGFVINSSEKLSLEDIIVIKTDEVDKIYKTLENYK
                     KDMIQAPFGEGHGEKINSEIANNTIIEKAGRYVYLISAENATQIENKILNIIKK"
     gene            47588..48232
                     /gene="uppS"
                     /locus_tag="PC494_001336"
     CDS             47588..48232
                     /gene="uppS"
                     /locus_tag="PC494_001336"
                     /EC_number="2.5.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="di-trans,poly-cis-decaprenylcistransferase"
                     /protein_id="HDF3911841.1"
                     /translation="MRIPKHVGIIPDGNRRWASQNGMTKDKGYESGIDPGLESYRLCR
                     DLGCEEVTFYGFTTDNTRRPSVQTKAFTKACIDAANILIDEGAALLVVGNTKSPMFPE
                     ELLPYTNRIKAKEGQIKANLLVNYGWYWDLNNISGVENVNKNNIQDYIQSFDVSRLDL
                     IIRWGGRRRLSGFLPVQSIYADFYVIDNYWPDFKSDDIKDAFSWYDTQDVTLGG"
     gene            48275..49180
                     /locus_tag="PC494_001337"
     CDS             48275..49180
                     /locus_tag="PC494_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HDF3911842.1"
                     /translation="MKKKLLDGKITLIICKSVKIYTKKGEEMSKGNNNNNSRNKSKKT
                     SHLNRKKRKLNKKKLAVLICFTVLFLFIAFKATQGVVALVKSMDKSNKTNQQQNVNSE
                     QFDLGNEEENKKKKYTVFIDPGHGGNDKGTESKTSNRYEKDLNLQIAKKLANKLSKQK
                     DIQVVVSRTDDTYISLKDRAILANNSSADVLVSIHLNAEKNGNTATGIETWYRNKATD
                     GSKELAQTVQSTIVSYVKVRDRGIVENNFEVLRESNMPAILIECGFLTTPSEEQKIIN
                     EKYQDQLAEGIVQGVLSYLDSKGNK"
     gene            49495..51042
                     /locus_tag="PC494_001338"
     CDS             49495..51042
                     /locus_tag="PC494_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HDF3911843.1"
                     /translation="MNKNSMTRIYSLNKIIFIIIGILGIVLLTRHIEVDIKVLILILL
                     TLFSINVFISYLKIKLYEDKINLGLINNSDKFINITKDENFLKHVQNYIISNEKENCV
                     MACFDLCRLKLINDIYGYELGDEVLNNILSNLKNYFGKEAIYGKLKSDVFVLIIKLEN
                     REQKIPYLVNLIKNKIVILSQIDSFKMDINIEASIGIYKFNNNEIDIKKAIDNADMAR
                     LKSKGLKHIEYVEFDNAMEEEIQSIMKIERDLFLAIKNKEFVIHYQPKVDSSTGNIIG
                     SEALIRWLHPSLGMVGPNKFIPIAEKNGLINNIGRWLIQEVFITINKWISEGINVLPV
                     SINLSRVELYKNDLVDFFKLMFNTYNIPKELIELEITETTALRDVKFISERLYEIKSL
                     GMNISLDDFGVGNSNFINLKGIPLDIIKIDRSLILDIVTNTKTKFMVKAIVNLSHDLN
                     VTVICEGVEDMHQVKVLSELGCNFIQGYVFFKPLDEMNYKKLLTDGSYINLKDTLLDK
                     CMTVEEE"
     gene            51045..51443
                     /locus_tag="PC494_001339"
     CDS             51045..51443
                     /locus_tag="PC494_001339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HDF3911844.1"
                     /translation="MISEDVDYSIRIIRAIFNNGEDKPIDAKMILKSEDIPILTLYRL
                     LRKLCANNILTFNKEDGKTYMLNVSLDTISLRTIVEVIDGKIYINKCTRYVSNCSNCL
                     KGCKVNRELLEIEKEIYKLLSRKSIRQILE"
     gene            51483..53216
                     /locus_tag="PC494_001340"
     CDS             51483..53216
                     /locus_tag="PC494_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-6 DNA methylase"
                     /protein_id="HDF3911845.1"
                     /translation="MDDISQDNFLLSKEYENSLDVDTKKASGIYYTPKIIVDYIVKKT
                     LKNHDIIKNPYPRILDISCGCGNFLLEVYDILYDLFEENIYELKKKYDENYWTVDNIH
                     RHILNYCIYGADIDEKAISILKDSLTNKKVVNDLDESDIKINLFCCDSLKKKWRYKFD
                     YIVGNPPYIGHKKLEKKYKKFLLEKYSEVYKDKADLYFCFYKKIIDILKQGGIGSVIT
                     PRYFLESLSGKDLREYIKSNVNVQEIVDFLGANIFKNIGVSSCILTFDKKKTKETYID
                     VFKIKNEDICINKFETLEELLKSSKFEHFNINQRLLSDEWILVNKDDETFYNKIQEKC
                     KYSLEDIAISFQGIITGCDKAFILSKDDVKLNLVDDKFLKCWIKSKNINKYIVDKSEY
                     RLIYSNDIDNENTNKRILDEIIGLYKTKLENRRECKSGIRKWYELQWGREKLFFERKK
                     IMYPYKSNENRFAIDYDNNFSSADVYSFFIKEEYLDKFSYEYLVGILNSSVYDKYFKI
                     TAKKMSKNIYDYYPNKVMKIRIFRDNNYEEIENLSKQIISILLNKSIDKGKVEKLQIK
                     MDNLIMDSLGI"
BASE COUNT        21432 a         5751 c         9610 g        16492 t
ORIGIN      
        1 tattcatatc atatatactc tataatatat ggaaaataaa gagaaaataa atggaaaata
       61 atcacaatat aaatataaaa tataaaaatc atcaggggga tatgaaaatg aacaaaaaaa
      121 tattatcatt aggtctagca gtatcattaa tcttagtaaa cttcaaaagt gtaaatgcat
      181 catcagtagt agaaaaaata tacggtaaag atagatatga aacagcagca aagatagctg
      241 ataaacagac ttatgaaaca gtaattttag taaatacaga aaaatcactt gcagatggat
      301 taagtgcaag tggattatcg ggagctacaa aagctccaat actatttaca caacaaaata
      361 agataccagc agacacaaat agatgtctaa aaaatatcaa aaaagcatat ataataggta
      421 cagaagatac tataagtaaa tcagtagaaa aagaactaga ttctaaaaat atagaagtca
      481 aaagaattgg tggagaagat agactaaaaa caagctattt aatagctaaa gaaatagcaa
      541 ctataaaaaa agtggataaa gtactattaa ctaatgcata tagtggagaa gcagatgcaa
      601 tgagtgtatc atcagtagct actagagatg gagctccaat catacttaca gatggaaaga
      661 gtgtgccttt tgatgtaaaa aatattcaat catattgtat aggttcagag gagataatga
      721 gtaatcctct agttaaaaat acaaactcag taagaataga aggaactgac cgatttgaaa
      781 ctaacaaaaa cgtaatagac tactttttta atagtgcaga tggattctat gtatcagatg
      841 gataccaatt agtagatgca atagcagctg caccacttac taaaaactct ccaatggtac
      901 tagtaaatga tggaagcgat aaaactgtat tagaaggagc taagaatata acctctgtag
      961 gtgaaataaa tgagaaggta atacaacagt gtataaatgc ttcaaattca aatgggcaac
     1021 ccccaacaat tacagttgga agtacagagg tatataaggg tgaaaagttt gacactggca
     1081 agttaaatat agtagctaaa gataacacag ggaaggtatt accaatagaa gttgatgggt
     1141 ttatagatac aaatagagta ggtacataca tattgacatt aaaagctaca gacgaatggg
     1201 gaaaaagcac aggaaaaaga gtagaaataa aagtgttgga tgacaaatct catgattaca
     1261 acagcccaga atttaaaaaa atggtatcta ctgaaatgta taacttaatc aattcctata
     1321 gaaaagaaaa aggcaaagag cctttgctag tgtctagtag gctagaaggt atggcaaatg
     1381 catggtctaa gtatatgatg gataaaaaag tatttgcaca ttatatagat ggaaaaaatg
     1441 ctccacaagt attttctgaa tttggaatga gaagtgagga aaatatagca tatatttata
     1501 tagattctaa gaacgttcaa acgacacaag atgcaaaaga cttggcaaag gctatatttg
     1561 aggtgtggaa gaagtctcca gagtacaatg caaacatgct tagtaatgag ttttatagta
     1621 ctggatttgg gctttatata ttatctgatg gtcaagtgca tgctactcag gagtttttaa
     1681 atggaaatga aggtagcttg taaaaaattc cataaatctt gtttttttgt taatttactg
     1741 atattataaa atgaaaatca catctaaagt actttttgta atctgttttg ttattgcttt
     1801 acaggctatg gtattttagg tgttttttgt tttagtagtt tatagatttt gagggaatca
     1861 ctactgagga tgtaatttat gattagctga attatataaa aaaattagta ggaggagttt
     1921 gatgaaggta aataagagag tattatcaat aggattgaca atatcattaa taatggcagg
     1981 agcaccaaat atcaatgcac tttcgagcat agaaaagata caggggaaag atagatatga
     2041 gacttctgca ttgatagcag ataaacaaat atatgataca atcatattag taaatactga
     2101 taattctata gtagatggat taagtgcaag tggattatct ggagttgcaa aagctcctat
     2161 aatgttggtg caaagagata agataccaac agatgttgaa aaaagactaa aggatgttaa
     2221 gaatgcttat gttataggta cagaggatac aataggtaaa tctgtagaaa atcaacttaa
     2281 gaataaaggg attgaagtta aaagaattgg tggggaagat agaataaaga ctagctatct
     2341 tatagctaag gagatttcag ctattaaacc agtaaatgat ggtgataagg tttttcttgt
     2401 aaatggatac acaggtgagg ctgatgcaat gagtgtatct tctgtagctg ctagagatgg
     2461 agttcctgtg atacttactg atggaaagag tataccattt aaagttgatg gcgttcagtg
     2521 ctattctctt gggtcagagg agataatgag taatgaactt gtgagtaaga ctaattcagt
     2581 taggattgct ggtaaggata ggtttgaaac taataagaag gttatacaac gcttttataa
     2641 aggaacaaag aagttttatg tttctcaagg gtataagtta gttgatgctg tggctggttc
     2701 tccgttggct aaggacaaac ctatagtact tgttaatgat ggaagtgata agagtgtgct
     2761 tagaggtgct gatgaagtta cttctttagg tggaatggat aagaaggttg ttgaccaatg
     2821 tattagttct gcatctgata aaaatacaat gcctacaatt actgctaatg atgtagagat
     2881 ttctgtaggg gataagtttg ataatagtat gttgaatata gttgctactg attattatgg
     2941 aaatgattta aaggcaaata ttaaaggaaa tgttgatatt aacaaggctg gaacatatgt
     3001 tttaaatata agtgtagtgg ataatttagg tcagaagagt gagattagtg taaatgttaa
     3061 ggtagttgta aatgcgagta caaaagactc taatagttat gagtttaagg ctatggtatc
     3121 taatgagatg tatgatttag ttaattcata tagaaaagaa aaaggcaaga agagtttaag
     3181 agagttagac tctttagctg gaatggcaaa tgcatggtct aaatatatgg aagataagaa
     3241 ggtatttgcc catgagattg atggtaaaaa tgcagctgaa gtattttttg gctttggagc
     3301 aagaagtggt gaaaatattg catatctacc aatgaatgtt aaatctgttt atacttctaa
     3361 agatgcaaaa gaaatggctg agtctatttt tgatttatgg aagaagtctt ctaagtataa
     3421 tgaaaatatg ttaaaagaag aattttatag ctttggattt ggtatgcatg tttctagtaa
     3481 aggagaagtg aatgcgacaa tggaattttt aaatagttag attttatatt aatttacatt
     3541 ggaaaagata tagtaaattt gtaaaaataa atatataaaa ttaaaataac ttataaaatt
     3601 ataaaaaata atttaaaaat aataaaaatg atgaaaaaac aattaatttg ttggaaaaaa
     3661 cttcaattaa ttttgcataa attattgaat ttatatttta tatagtctat cataagagtg
     3721 tgagaaatat ttggattata tgaacatgga aatttaatgt acataattaa agagatgtaa
     3781 ttaatataat gttgggagga atttaagaaa tgaataagaa aaatttagca atggcaatgg
     3841 cagctgttac tgttgtaggt tctgctgctc cgatatttgc tgatactact gttaaagaag
     3901 aaggatatac ggtagtacaa gacaaatatg aaaaattact taaagaatta aaggcaaaga
     3961 taaaagatgg aactattaca tcagttggtg ttgaatttga tggaaaacca attactacat
     4021 tagcaccaaa ggcagatggt agtgataaag atgcaatagc agaacagtta gaaactctta
     4081 ctaaaaacca acttaaaggt ttaggtgatg gaaaatatgt agattttaaa attacttatg
     4141 gtgctaaagc agaagttcca gctgcttcat taagtgcaga tgatatacaa aaatatgcag
     4201 atcaaataaa tgcttctgag aaaatattag ttgaagtagc agcaggatct gaagcaggta
     4261 tagcaaaatt tgattctgtt aacaataaag ttatagcagg agatgctcct cttaaagtta
     4321 aagatgcagt gaaagcgact gttactacta atggtagtaa taaaaaagtt cttacaatat
     4381 cagctgcagc tggattatca ggattttcat atggaacact taaagacaca ggtgcaagtt
     4441 tatctgatgt tgatgcaata actcttgaca ctacaaatgc aacaataaca gaaggtgata
     4501 ctaaagtatt agattttgat aattcattta agtttaacga aagtactaaa aaagttggta
     4561 gtttagttac accaaataca acaaacactc cagcagatcc tggtactaaa actactgtta
     4621 gagtgataaa agctgttgaa aaaacaatag atgtaagttc aaattcaact acaaaagcta
     4681 aagatttagc taaacaatat gtattcacag atgttagtga tactgatcca gaaagtttaa
     4741 gttatatgct taaaaacata aatgatggaa aagttgctgt taaaaattct gatggagatt
     4801 atgaagtaac tatattccca gaaggaaaaa gattaaatac tttatctgct tcttcagcta
     4861 aaactatttt aggagataaa gatactccag caaaaatagt tttaaaggct tcaacaacaa
     4921 agaaattagc agactatata gatgatttaa taacttataa caatagttat tcaaatgtac
     4981 aaactgtagc aggtagtgat agaatagaga ctgctataga gctaagccgt aagtactata
     5041 actctactga caaaaatgct ttatatggag atcctgtaaa taacgttgta ttagtaggtt
     5101 ctcaagctat agttgatgga ttagtagcat ctcctttagc agcagaaaaa gatgctcctt
     5161 tattgttaag ttctaaagat aaattagatt catcaacaag agctgagata aaaagagtta
     5221 tggacttaaa ttcttcaaca ggaataaaaa ataataaaga agttttcata gcaggtggag
     5281 taaattctat atctaaagac gttgaaaatg aactaaaaga tatgggactt aaagtaacta
     5341 gattatcagg tgatgataga tatgaaactt cattagcgat agctgatgaa atagatataa
     5401 atgataaagc ttatgtggta ggtggaacag gattagcaga tgctatgagt attgctccag
     5461 ttgcatctca aataaaagat ggtgaagcta ctccaatagt agttgtagat ggaaaatctg
     5521 acaagttatc taaagaagct gaagatttct tagatgatgc acaagtagat ataatcggtg
     5581 gagaaaatag tgtttctgct aaaatggaag attatataga tgatgctact ggaaaatctc
     5641 cagaaagaat tagtggtgct gatagacaag caactaatgc tgaagttata aaagaatact
     5701 ttgataaaga tggagtttca aattacttct tagcaaaaga tggttcaact aaagaggatc
     5761 agttagttga tgcattagca gcagcagcag tagctggaaa ctacggttct aagcataatg
     5821 aagatggaga tataactaca gatgcttctc ctgctccaat tattttagca actgataatt
     5881 tatcagctga acaacatgta gctgtaagta aaactgctac tactaatggt gctaagaact
     5941 tagtacaagt aggtcaagga atagctgatt cagttgttag caaattaaaa gatttattag
     6001 atatgtaata taaattttat atattgaata aaaaaggttt ctcttttgag aaaccttttt
     6061 tattttaaac ataaattttt ataaataaaa agaggctaat tagcctcttt ttaatgtgag
     6121 aaacacttaa aaaataagat gtaattattt atttaagtat cattattata ctatacctta
     6181 aaataaatgt ctactattct ataattttaa ggtataatag taagtggaaa ataaataagg
     6241 aggtaaatta aatatgtcag ttttagatgt aatattagac aaaacagatg aattagaaat
     6301 taaaaaatta aataatatag tagataaaat agatgcttta gaagataaaa tacaaatact
     6361 agatgatgaa gcattaaaaa atatgacgaa tgtatttaag gataagttaa gtaaaggaga
     6421 aaccttagat gacatattgc cagaagcatt tgctgttgta agagaagtat caaaaagaat
     6481 attaggtatg cgtcaatata gagttcaatt aattggtggg attgtattac atcaagggaa
     6541 aatagcagag atgagaactg gagaaggaaa gactctagta ggagtagctc cagtttactt
     6601 gaatgcattg actggtaagg gggtacatgt catcacggtt aatgattact tggctcaacg
     6661 tgataaagaa cttatgcaac cagtatatga atttttaggt ttaacagtag gagtaattat
     6721 taatgggcaa cagccagtag aacgaaaatt acaatatcaa tgtgatatta cttatggtac
     6781 aaacaatgag tatggattcg attatttaag agataatatg gtaacgcaaa aatcagagaa
     6841 agttcaaaga gaactaaact ttgctatagt tgatgaggtt gattcaatac ttatagatga
     6901 agctagaaca ccacttataa ttgctggtgg aggagatgaa ggtactaagc tgtatgaact
     6961 tgcaaatgct tttataaaga atataagaga tgaagatttt gaaatggata gaaaagataa
     7021 aaccatagca cttactgcaa gtggtcttag taaagctgag aaattttttg gaatagaaaa
     7081 tataactcat atagataata tagaaatttt tcaccatgta aatcaatctc taagagcaca
     7141 taaattaatg aacatagatg ttgaatatgt tgttagagat aatgagatac taattgtaga
     7201 tgaatttaca ggaagaataa tggatggaag aaggtttact gatgggcttc atcaagcaat
     7261 tgaagctaaa gagggagtaa aaataaatga tgaatcaaag accatggcaa cagtaacatt
     7321 tcaaaatttc tttagattat actctaaatt atcaggaatg acaggtacag caaagacaga
     7381 ggaaagtgag tttgaagcta catataagat taatgttgtt cagataccaa ctaataaacc
     7441 agttataaga gctgatttac atgataaagt attcaaaaca gaacgtgcaa agtacaatgc
     7501 tgttgtagaa gaaataataa ggataaataa aactaagcaa ccagtgcttg taggaactgt
     7561 ttcaattgaa aaatctgaga aattatctaa gctacttaaa aagaaaggtg taaagcacga
     7621 ggtcttaaat gctaaacaac atgataagga agctgaaata atatctaaag ctggtaaatt
     7681 aggttctgtt acaattgcta ctaatatggc aggtagagga actgatatat cacttggagc
     7741 tggagataaa gaagaagaag aaaaggtgaa agagttaggt ggcttgtatg ttataggtac
     7801 tgaaagacat gagacaagaa gaattgataa tcagcttaga gggcgttcgg gaagacaagg
     7861 tgaccctgga acttctagat tctttgtaag tttagaggat gaagtaataa aattgtatgg
     7921 tggaaaaagt atagaaaaaa tattaaagag aatgaatgct aatgaagatg acgcgttaga
     7981 aagtaaggct ttgaatagag caatagaaag agcacagaaa ggcattgaag gtaaaaattt
     8041 tgaacaaaga aagaatgttc ttaagtacga tgatactatt aatgagcaaa gaaaagtaat
     8101 atatgatgaa agaaataagg tattggatgg ttctgatatt gaagaagaga tacaaaaaat
     8161 ggttatggat attattacgg aggctgctga aaagtactta aaaaaattta gagactatca
     8221 tggatatttt aagtatttat ataatacttt tatgccagct gatactttat taattccaga
     8281 cttagataaa aaaaatgttg aagaaatagt aaatcaaaca tatcagattt caaagcgtgt
     8341 ttatgatctt aagaagatga tgattggaat tgaagaattg gctcaattag agaaacgagt
     8401 attacttcaa gttgtggata cttattgggt tgaccatata gatgcaatgg atcaactaag
     8461 acaatatata ggtcttaaat cttatgcaca aaaagatcca tttaaagagt atgctataga
     8521 aggttatgaa atgtttgaag ctttaaatag gaatataaga ataacaacag tgcaatatct
     8581 atataaattt aactaaaaaa gtgacccatt gggtcacttt ttatatatta agattaaagt
     8641 gaaatttatt ttacagtaca cactcatata gataaatatt tataataatg aaaaagaggc
     8701 tgaacgtcag cctcttttcc tgtgtgagaa atacggaaaa aagagatgct tgaaatttct
     8761 ttcttccatt taatattata ctataaagag aataaaaagt ccatgagtta tctttatgat
     8821 taaaaaaaaa aattacaatt ttgttacttt ttagtataca ataataaatt taaattgact
     8881 ttgttaattt ttattaataa aatatccaaa tattacaata tctacagttt attgaaataa
     8941 tgtgtaaatt atattataat tggtaaataa ggaaaaatgg tgaaaaccaa attttgtagg
     9001 gggaaatata tgaatagaaa aaatctttat gtaattatgg cagctgcaat ggtaagtaca
     9061 tcagtagctc caagttttgc tgcagaagct acacaagtaa agaaacaaac aataactaaa
     9121 aaggaagcaa cagaattagt ttctaaagtt agagaactaa tggctcagag atatacagga
     9181 ggttctcaag ttggacaacc aatatatgaa ataaaagttg gtgaaacttc atcacaatta
     9241 aaaataataa ctaatataga cgaattagag aaattagtaa atgctttagg agaaaataaa
     9301 gagcttcttg tgactatagc agataaagga catacaacaa atagtgcaaa tgaagtggtt
     9361 gctgaagcaa ttgaaaaata tgaaaattca gcagaccttt cagctgaagc taattcaata
     9421 acagaaaaag ctaaaactga agctactggg atttatggag tggcaactgt agaagcttca
     9481 tatgacagta caaaagataa gttagtaata actttaaaag ataagactga tgtagtaact
     9541 tctaaaacgc tacaaatagg tattggtgat gaaaaggttg atttaacagc aaatccagtt
     9601 gatatagcag gaaccaattt agacccttct gcagaaggat ttagagtaag taaaataaat
     9661 aaattaggtg tagaaggagc taaaaatatt gctgatattc aattagctga aataactata
     9721 aaaaatagtg atttaaatac agtttcacct caagatttat atgatggata tagattgact
     9781 attcgaggta atacaatagc aaatagtgta ggaaaatcaa ttagtgatat ttcatcaaaa
     9841 gattcagaga caggaaagta taaatttact gttaaatata ctgatacatc tggaaaagcg
     9901 atagaactta ctgtagaaag tactaatgat aaagagttaa aagatgttaa agatgcctta
     9961 aatggaaata caaaagtcaa tttaatagct ggggaagaca ggtatgcaac tgctgtagct
    10021 atagcaaaag aaacagaata tactgacaat atagttatag ttaattcaaa taaattagtt
    10081 gatggattag cagcaacacc actagctcaa tctaaaaaag ctcctatatt gttggcgtct
    10141 gataatgaaa taccaaaagt aactttagat tatataaagg aaataattaa aaaaagtcca
    10201 tcagctaaaa tatatatagt aggtggagaa tcagcagtat caaatacagc tagaaagcaa
    10261 ttagaatcag taactaagaa tgttgaaaga ttggctggag atgatagaca tacaacttca
    10321 gtagcagtag caaaagctat gggttctttt aaagaagcat ttgtagtagg tgcaaaaggg
    10381 gaagctgatg ctatgagtat agctgctaaa gctgctgaac ttaaggctcc tataatagta
    10441 aatggttgga atgatcttac agcagatgct atcaagttga tggatggaaa agagattggt
    10501 atagttggtg gttctaataa tgtacctagc caaattgaaa atcaacttgc tgatattgat
    10561 aaagatagaa aggttcaaag agttgaaggt gaaacaagac acgatactaa tgctaaagtt
    10621 atagaaacat attatggcaa attagataaa ctatatatag caaaagatgg atatggaaat
    10681 aatggtatgt tagtagatgc attggcagca ggtcctctag cagcaggaaa aggaccaatt
    10741 cttttagcta aaaatgatat aacaaactca caaaagaata ctttagataa aaaactaaat
    10801 cttggtgcag aagtaactca aataggtaat ggggttgaat tgactgtagt tcaaaaaata
    10861 ggcaaaatac taggatggta ataatcaata atatagaaaa ggattcctta ttatttatag
    10921 gaatcttttt ctatcgacat aatattcatt aaagtataac atgctcttga cagataggag
    10981 gatatgatag tgatagaagc aacattgttt ttttccccac accaagatga tgaaacatta
    11041 agtatgggta gtgcaataat tgaacatgta gaaagaagcg atacacatgt tatattatgt
    11101 actgatggca gtaaatcaat aataagaaaa gtattagatg atggagggtc atgttcttat
    11161 catattaaag atgtacacaa gtactcttta tcagaaagtg atttttcaaa aaatagagat
    11221 gaagaattta aaaatagttg taaagcaatg ggagttaaag aaaataatat acatatagaa
    11281 aataatagag ctcatgatgg agaattgagt aaggaaaaag caagagatat aatgctaaaa
    11341 tatttagaaa aatatcctga tgctaaagtg aagaccgtta caccatataa agctcttgga
    11401 atacatgaag accatagagc attaggtgaa gctgcattag aattgtatag agaaggaaaa
    11461 ataaaagatt taagatttta tgtagagcca tacgattata atgattttaa aaaagttaat
    11521 ccaaatgtta gagtatggaa ggttttgagt agtcaagaag agaaattatt aaatgctatg
    11581 gatgcataca agaaatggaa tcctgaaaat ggtaactacg caattggata tcattctgta
    11641 aaatctcact ttgatgaatt aaaatccaat aaaatccaat atgtacatgc tccataaaca
    11701 ttaatataaa aactaggagg atatagttaa tgaaaatatc taagagaata atgtcgttgt
    11761 tgacagcaac tttttttatc tttgcattat ctatcaatat agctgatgct tcatcaaaag
    11821 agagtctagt gggctctggt agatgggaaa ctgcaataaa aattagtcag aatggatgga
    11881 aagatgctac taatgctata ctagtaaatg ataattctat agctgatgca ttatctgcaa
    11941 ctccatttgc taagttaaaa gatgcaccta ttttattaac tcaaagtgat aaattggata
    12001 gtagaactaa agcagaatta aaaagactag gtgtaaaaaa tgtatattta attggaggta
    12061 tgaatactct aagcaccaat attgaaaaac aattaaaatc agaaaatatg acttttgaga
    12121 ggatttcagg taatagtaga tatgaaacat ctttaaaatt agctgaaaga ttagataaag
    12181 agaagagtat ttctgatata gttgtagtta atggagagaa agggctagca gatgcagtaa
    12241 gtgtgggttc tgctgcagca caagaaaata tgccaattat actttcagat cctaacaatg
    12301 gaataaaagt tgcaaatagc tttattagta gtaaaaatat aaagaaatct tatataattg
    12361 gtggtacata ttctgtatct agttctattg aacagagttt acctaatgta aaaagattat
    12421 ctggaaacaa tagaaatgaa actaatgcaa aggttctaga agaattttat aaaaatacag
    12481 acttaaaaaa tgcttatata actaaagatg gtatgaaaaa acagggggat ttgatagatt
    12541 ctctagctgt aggtgtattg gcagctaaaa atagctctcc agttgtatta gtaggaaatt
    12601 cacttgactc tagccaatat gatgtgttaa atactaaaag ttttgataat attgtgcaag
    12661 ttggtggaaa tggaaatgaa gatgctgtaa aggatattct tgatttacaa gaagaaacta
    12721 tatatagagt taagacagca gacgaattgg atgttgctct aagaaaagca gatgctaatg
    12781 atattataac atttaaacct gatgataata aaaaaattac tagttcattt agtatagaaa
    12841 caaagaaagc tataactgta gagcttgaag gattgtatac acaaacaata actgtaaata
    12901 tgccaaatgg agaattaact aataagggta cattagatgg aactgtgaaa ataatggata
    12961 taaaaaatgg cacatttatc aatgaaggtg atataaatga tattgacatt tatgatccaa
    13021 atggatgtaa aatagagaat aaaagtggtg gagatatatg ggttttaact atatctagta
    13081 gtgctaaaga tgtaaatata gaaaataaag gtgatataag taaggttaca aataattcta
    13141 ctagcgttat aataagaaat tcaggaaata ttgatacttt aagtggaatt aatgcaccag
    13201 caataagtgg aaataaacct agagttgatg ataccgataa ggatgaaaaa agagcaagtg
    13261 gaatatatcc tacttcagaa cctttatcac ctgcaagagc tggttatata agtgtaaaaa
    13321 tattcactaa gcctgaagat acaaattata aaatttatta tagagtagta agcagtagac
    13381 catctgcatt atatatcgga gatagaatag atacaagtga ctggactgct gtaccatctt
    13441 ctgttttacc atttactatt aaagcagaaa atggatatta tatagaagct gttgaaataa
    13501 attctgatac taagaaagta tctagatggg ggaaatctga ctatatagat gatggatttt
    13561 atttaaaatc agaaactgca aaaggattaa gtgcagatat agattttgat ggagattatg
    13621 ttaaattaac agcaacaggt gctgattctg gatgtacagt ttattataga atagtatcaa
    13681 aaaagccagt atcaatgaat gttggagata aagtaactat atctgattgg gatgaaatta
    13741 ctactaatag agtgaggata gaagcaaacg atgtaaagga taaatatata gaactagttg
    13801 aattggatga ttcaactaat aaagtaacta gatggggagc aagtgataag gtagtagaat
    13861 aggtatctaa tgtgaaacat aaaaacagac tgattaataa tgggcagtct gtttttattt
    13921 cctaaaaatt atcattttac taaataaata atttaaaact ataacaatta tattagtaaa
    13981 tacttttaca gtaatatcat ttacaaaaaa taaatcaatc attatataca taataatcat
    14041 ttctataata ccagaaagta gcctaaaact gacaaaaaac aaaaactcct taaacaaaaa
    14101 tattagttca attcttttac tctcaaacac aaaaaactta ttagtaacat aagcaaataa
    14161 aacagcaagt atccatgcca aagcatttgc aaccataaaa ttaaataaaa taactctagt
    14221 aaaaaataaa tacgaaacta tatttacaag agtagtaaat gctccaaaaa ataaatataa
    14281 tatcgtctct ctatgctttt ttaaaatcaa atataatcct cctaagctaa tttaatataa
    14341 atatacttaa agatactaac aaacattagt ataacacatc tattaataaa tcaatatatc
    14401 ttaaaatatt ataaaaataa aactataata ttctataatt aatatgtact cataatccat
    14461 attttatcaa aataaaatat gaccttaatt tagaaatctg atataataaa aattaaatac
    14521 atataagggg gtaaacatga gaaagtacaa atcaaaaaac ttgtcaaagc tactagcatt
    14581 gttgacagtt tgctttttaa tagtgtcaac aatacctgtc tcagcagaaa accataaaac
    14641 tctagatgga gtagaaactg cagagtattc tgaaagctat cttcaatacc tagaagatgt
    14701 caaaaatgga gacacagcaa aatataatgg agtaatacct tttccacatg aaatggaagg
    14761 tacaacactt cgaaataagg gtagaagtag tcttccatca gcatataaat caagtgtagc
    14821 atacaaccca atgaatcttg gtcttactac accagcaaaa aatcaaggaa gtcttaatac
    14881 atgctggtct ttttcaggta tgtcaacgtt agaagcatat cttaaattaa aaggatatgg
    14941 aacgtatgac ttatcagaag aacatttaag atggtgggca actggtggaa aatatggatg
    15001 gaacttagat gatatgtcag ggagttcaaa tgtaacagct ataggatatc tgacagcatg
    15061 ggcaggtcct aagttagaaa aggacatacc atataatctt aaatctgagg cacaaggtgc
    15121 aactaaacct tcaaatatgg atactgcacc tactcaattt aatgtaacag atgttgttcg
    15181 tcttaataaa gataaggaaa ctgtaaagaa tgctataatg caatatggtt cagtgacatc
    15241 aggttatgca cattattcaa catattttaa taaagatgaa acagcatata actgtacaaa
    15301 taagagagct ccattaaatc acgctgtagc gatagtagga tgggatgata attattcaaa
    15361 agataatttt gcatctgatg taaaaccaga atcaaatgga gcatggttag taaaaagtag
    15421 ttggggagag tttaattcta tgaaaggatt cttctggatt tcttatgaag ataaaactct
    15481 actaacagat acagataact atgcaatgaa atcagtatca aaaccagata gtgataaaaa
    15541 aatgtaccaa cttgaatatg ctggtcttag caagataatg tcaaataaag taacagcagc
    15601 aaatgtattt gattttagca gagactctga aaaacttgat tctgttatgt ttgaaacaga
    15661 ctctgtagga gcaaaatatg aagtatatta tgcaccagtg gtaaatggag ttcctcaaaa
    15721 caattcaatg acaaaacttg caagtggaac agtatcatat tctggataca taaatgtacc
    15781 tactaattct tacagcttac caaaaggtaa aggagcaata gtagtagtta tagacaacac
    15841 agcaaatcct aatagagaaa aatcaacttt agcatatgaa actaatatag atgcatatta
    15901 tttatatgag gctaaagcaa acttaggtga aagctacata cttcaaaaca ataagtttga
    15961 ggatataaat acatatagtg aattttctcc ttgtaacttt gttataaaag ctataacaaa
    16021 aacatcttct ggacaagcta cttcaggaga atctttaact ggagcagata gatatgaaac
    16081 agcagttaaa gttagtcaaa aaggatggac ttcttcacaa aatgcagtat tagtaaatgg
    16141 agatgcaata gtggatgctt taacagctac accatttaca gcagcaattg actctccaat
    16201 tcttttgaca ggaaaagata acttagattc aaaaactaag gcagagttac aaagattagg
    16261 aactaaaaaa gtttatctaa taggtggaga aaattcttta agcaagaatg tacaaactca
    16321 acttagtaat atgggtatat cagtagaaag aatttcaggt agtgatagat acaagaccag
    16381 tatatctcta gctcaaaagt taaatagtat aaaatctgtt tcacaagttg cagtggcaaa
    16441 tggtgtaaat ggacttgcag atgcaataag tgttggtgca gcagctgctg ataacaatat
    16501 gccaataata cttactaatg aaaaaagtga gttgcaaggt gctgatgagt ttttaaattc
    16561 atctaaaata actaagtctt atataattgg tggaacagct actttatcat caaatttaga
    16621 aagtaagctt tcaaatccaa caagacttgc aggcagtaat agaaatgaaa ctaatgctaa
    16681 gataatagat aaattctacc ctagctcaga tttgaaatat gcttttgttg ttaaagatgg
    16741 ttcaaagagt caaggagact tgatagatgg actagcagta ggagcattgg gtgctaaaac
    16801 tgattcacca gtagttctag ttggaaataa gttagatgaa agtcaaaaaa atgtacttaa
    16861 gtctaagaaa atagaaactc ctattagagt tggtggaaat ggaaatgaaa atgcttttaa
    16921 tgaactaaat actcttttag gaaaatagtg aatggaaaga tagtaaggat atacatttta
    16981 ttattaaaaa atgttcaata gaagtttata aatataaaat aacaaaaagg ggtgtctcaa
    17041 aatgaacttt ttagttcatg aggcactctt ttttgttgtt ttatattttt atcatttaaa
    17101 taatgaaaaa taggattgtc tatattttta gatagttttc ttattattga tgaaaaatgt
    17161 aataatttta aactgtaaaa tagtgtaaag ttattttata atataaatat agtaagattt
    17221 taaacaaaat aagggggaat aataatgaaa gcaccaaaaa ctattttaac aatactgaca
    17281 atagcgctta ctttaagtag catttctata ataccatcat atgcacttac agaggaaaaa
    17341 ttaataggta atggtagata tgaaactgct gtaaagataa gtcaaaaggc atacagttct
    17401 agtcctaatg tagtgctagt taatgacaat tcattagctg atgcactttc agctacacca
    17461 tttgcaaagg ctaaaggagc accaatactt ttgacagaaa gtgataagct agatgatagg
    17521 actgaaaaag agataaaacg tctaggagct aaagatattt atttgatagg aggtactgct
    17581 gtacttaata aagatataga gaacaagtta aaaagtaatg gacttaatgt agaaagaatt
    17641 aatggtaagg atagatatga aacttcactg attttggcta ataagcttaa ggatataaaa
    17701 gatattaagg aagttgctgt agtaaatggt gaaaaaggat tgagtgatgc tgttagcgtt
    17761 ggggcaccag cagctcaaaa taagatgcct ataattttgt ctagtcctaa ggatggagta
    17821 gaagcatttg ataaatttat aagggatgag aaagttataa aagcatatgt aattggaggt
    17881 acaaattctg tttcaagagc tgtagaaaag agtcttccta atgcagaaag agtgagtggg
    17941 aaagatagaa atgagactaa tgctaaagtt atagaaaagt tttacactga tacaaattta
    18001 agtaatttat atgtaactaa ggatggtagt aaaaatgaga atcaactaat agactcgtta
    18061 gctgttggcg tattggctgc aaaaaatgag tctcctgttg ttttggttgg taataaatta
    18121 aacacaaaac aaagagatat acttagtact aaaaaattaa atactataac acaggtaggt
    18181 ggaaatggaa atgaagaagc ttttgatgaa attaaaagtc tacaagaaaa aactgtgttt
    18241 gaagcaaaaa ctgttgagga attaactgat atgataaata tagcaagtcc taatgatatt
    18301 ataaacttta aaccaaaaga gaatactgta aatgaagctt ttagaatggt aacaaataaa
    18361 ccaataactg tgaatataaa gggtgattgt tcaaagactc ttacagtaga tatgcctaat
    18421 ggtgaagtga ataactatgc tactttggta aatgttatag ttagaaatat tggagaaggt
    18481 ggatttaata atcatgatac aatcactata ttgtcagttc gtgacaaaaa tggtagagtt
    18541 atagaaaata ctagaaattc agatatagat acgttgatga tattagcttc tgctaatgat
    18601 acaaaattga ttaatgatgg atatatagga aaacttatag ataattcatc taatagtgat
    18661 ataactaata atggtactat agataaaaaa gttaatcagg ttgaagattt agaggctaaa
    18721 gtagattcaa ttgaaaaagc tatagattct ataagtcaaa aagtcaataa aatacaagat
    18781 atactagata agcttggatt tctaaagaaa tttcttagct aagaatatgt atatttaagt
    18841 gaagtgtgtg ttgtaattgt tctaaagtta tgtagttaaa caggtttata tacaaataga
    18901 tttatagata aatatgtagt ttagtatata tttgaataag ctttggggag gtaacatggg
    18961 gattggaatt gaatgtaaca aaaaaataaa taaaagtatt gacaaaacta gaataaagaa
    19021 aaataatcta aatagcaata gcaatagcaa tagcaatagc aatagcaata gcaatagcaa
    19081 tagcaatagc aatagcaata gcaatagcaa tagcaataaa atttcaaata atgctgtaga
    19141 ttctaaactt atgaatagta ggattaaatc aatagatata ataagagggc tatcaatagc
    19201 cctcatgata gtctgcaata atcctgggac ttggatgaga atgtatcctc aattaagaca
    19261 tgctgtatgg catggtgtaa cacttgcaga ttttgcattt cctttttttg ttatatcttt
    19321 aggtgttaca attccaatat caataaatag taaactaaaa aataataaat ccacactgag
    19381 tataatactt agtatattca agagaagtat cttattgata ttatttggat ttttcttaaa
    19441 ttacctagga aatcctgatt tagatactgt aagaatactt ggagtacttc aacgtatggg
    19501 attagtctat tttgtgacta gtttagcata tttactgcta aaaaaattaa atgttggaag
    19561 tactgctaca ataattactt ttctatatat agctacattt ataatagttg ggtactacat
    19621 cttagcaaaa ccttatggat ttgagctaga aggttctctt gcacagttag tggatttaca
    19681 tttcttcaaa ggacatttgt acaagccgga atttgaacca gatggttttt taactagtat
    19741 agtagcaatt tcttcaggta tgttgggatg cactatggga tgtgtacttt taaaagaaaa
    19801 cctaggagaa tataaaaaat tctttaaaat actggttatg agcataatcc tgctaatagg
    19861 tgcttttatc tttaatcagt attttccatt taataaaaga ttatggtcta gctcatttgt
    19921 acttttaatg gctggcagtt atggtatatt actgtcaata ttttatttta tatgcgacat
    19981 caaaaataaa agtaaaatat ttaccccaat aatagcactt ggaagtagcc ccatttttac
    20041 atatatgtgc cttgagatat tgagtcatgt tttttggaat gttccaaaac ttacgaacaa
    20101 agtcgattat ccaactacct tggtagagtg gactacatat gaacttataa caccttgggc
    20161 aggtacaact tgggattctc ttatattttc tttattgtat gtcctattct gggttatagt
    20221 aatgtctata atgtacaaga aaaaaatatt tattaaaatt tagtgcaata tttttagatg
    20281 ataaagtctt tgatttgttc aaatatacag aaactatcaa atataatcaa aatttctcct
    20341 cgataaaatt taaaaaccat gccataaaag attacaaaaa gtttacaatt tgtaattttt
    20401 tgtgctataa tgaaaaaaga tttacataat attgaattta tgtaatataa aacaagctta
    20461 agatgtatta aaaaagattt aaagatttaa agaaccaaaa aattaggggg gatatgatga
    20521 aaaaaacaac aaaattattg gcaacaggaa tgttgtctgt agcaatggtg gcaccaaatg
    20581 tagctttagc ggctgaaaat actactgcaa atacagaatc taattcagat attaatataa
    20641 atttacaaag aaaaagtgta gtgttaggaa gtaaatctaa tgcaagtgta aaatttaaag
    20701 aaaaattaaa tgctgattca ataacattaa attttatgtg ttatgatatg ccacttgaag
    20761 ctactttaaa ttacaatgaa aagacagatt catatgaagg tgtaataaac tataacaaag
    20821 acccagaata cttaaatgta tgggaacttc aaagcataaa aataaatggt aaagatgaac
    20881 agaaagtttt aaacaaagaa gacttagagt ctatgggatt aaatcttaag gattatgatg
    20941 ttacacaaga gtttataata agtgatgcaa attcaacaaa agcagtaaat gaatatatga
    21001 gaaaaacttc tgcaccagta aaaaaacttg ctggagctac tagatttgaa actgctgttg
    21061 agataagtaa acaaggttgg aaagatgggt ctagtaaggt tgtaatagtt aatggagaat
    21121 tagcagcaga tggaattaca gctactccac ttgcatctac atatgacgca ccaatattac
    21181 ttgcaaataa agatgatata ccagaaagta caaaagcaga gttaaaacgt ctaaatccaa
    21241 gtgatgtaat aattataggt gatgatggtt cagtttcaca aaaggcagtg tctcaaatta
    21301 aatctgctgt aaatgtaaat gtgactcgta ttggtggagt tgatagacat gaaacatctt
    21361 tacttatagc aaaagaaata gataagtatc atgatgttaa taaaatatac atagcaaatg
    21421 gatatgctgg tgaatatgat gctcttaata tttcatcaaa agctggtgaa gaccaacaac
    21481 ctataatatt agctaataaa gattctgtac cacaaggtac atataattgg ttatcttcac
    21541 aaggtttaga agaagcttat tacataggtg gtagtcaaag tttatcatca aaaattatag
    21601 accaaatatc taaaatagca aaaaatggta cttcaaaaaa tagagtttct ggagcagata
    21661 gacatgaaac aaatgcaaat gtaattaaga ctttctatcc agataaagag ttgagtgcaa
    21721 tgttagttgc aaaatctgac ataatagttg attcaataac agcaggacct ttagcagcta
    21781 aattaaaagc tccaatactt ataactccaa aaacttatgt ttctgcatac cataatacaa
    21841 atttatcaga aaaaacagca gaaacagtat atcaaattgg tgatggaatg aaagatagtg
    21901 ttataaattc tatagcatct agtttatcaa aacacaatgc accaacagaa ccagataatt
    21961 caggttcagc agcaggaaaa actgtagtga tagacccagg tcatgggggt tctgattcag
    22021 gggcaacaag tggattaaat ggtggagcac aagaaaagaa atatactctt aatacagcat
    22081 tagcaactac tgaatattta cgttcaaaag gtataaatgt tgttatgact agagatacag
    22141 ataaaacaat ggctttagga gaaagaacag cattatcaaa tactataaag ccagatttat
    22201 ttacaagtat acattacaat gcgtctaatg gagctggtaa tggtgtggaa atttattaca
    22261 aagtaaaaga taaaaatggt ggaacaacta agactgcagc atcaaatatc ttaaaaagaa
    22321 tactagaaaa atttaacatg aaaaatagag gaatcaagac aagaacactt gataatggaa
    22381 aagattacct atatgtgtta agaaataaca attatccagc aatacttgtt gaatgtgcat
    22441 ttattgacaa taagagcgat atggataagt taaatactgc agaaaaagta aaaacaatgg
    22501 gaactcaaat tggaatagga atagaagata cagtaaaata aaatagaaaa tattaaagca
    22561 aaacatatca tctcctgtta taatgtaaaa tataacaaga gatgatatat ttttgtaaag
    22621 aatcaaattg tttacaatga tgtttcttgt attgataatc tgctcattat tgagtataat
    22681 atagaaataa gtcaaaaata agatagaaat aagttgaaat taagaattaa aaaaattttt
    22741 attccaatat ggaggtaact atgtctggat atactaatga tgagtgtgaa atacctaaaa
    22801 ttaaaagcta tccaggggca gataaagaaa ttgcaagtga gattgactat agcatagtaa
    22861 aaggaacagt tttattcgac ttgtaccaaa gaattatgga tttagtttta tctataatag
    22921 gacttgtgat aggtttacct ttaatagcaa tatttggaat tcttattaaa atagaggaca
    22981 aaggaccaat aacttataag caagaaagac taggaaaatg cgggagaaga ttctatatat
    23041 ataaattgag atctatgaga acagacgcag aaaaatttgg cgcacaatgg gctgaaaaag
    23101 atgatcctag aataactaag gttggaaagt ttattaggaa aactagaatt gatgagattc
    23161 cacagctgtt taatatatta aagggggaca tgggcttaat aggtcctaga ccagagagac
    23221 cgaactttac tgttcaattt aatgaggaaa tacctggatt tatcaacagg ctcgctataa
    23281 aacctgggct tacaggttgg gcacaagtaa atggtggata cgaaatcact cctgaagaaa
    23341 aacttaaaga agatatttac tatataaaaa ataggagtat attacttgac tttaagatac
    23401 tctttaaaac tgttaaagta gtattgacag gagacggagc tagataattt taaaatatta
    23461 gattactaat caatgaaaaa gctctttaaa aagagctttt ttattgtcaa aaaatacaaa
    23521 aaagaaaagg aatgagaact tatgattaaa aaaatttcta ctatattatc gttagttttg
    23581 ttaatctcta tttctagtac gataggagta tttgcagatg caaatcccaa aagagaattg
    23641 atagaaggga gtataccaga gatttcgaca gaattaaata aaagagcatt taaggattct
    23701 aaagaagtaa ttcttgtaaa tgaagagtca attgtagata gtataagtgc aacaccttta
    23761 gcatatgcaa aaaatgctcc aatagttgta actaagagta aaaatcttgg tagagtaaca
    23821 agaaattatc taaaagaact aggtccagag aaggttacga tagtaggtgg tttaaaggca
    23881 gtatctaaag atgctgaacg taatatagaa aaaatgggaa tgaaagtaga aagaataaga
    23941 gggaaagaca gatatgatac atctttaaag atagctagag aaatgtatag aacagtagga
    24001 tttgatgaag catttttact tagctcaaca acaggattag agaacgccat atctgtatat
    24061 tcttatgccg ctaaaagtgg aatgccaata atatgggcta aagatgaagg gtttgaggaa
    24121 caaattgatt tcttaaaagg caaaaatctt aaaaaaatat atgcattagg tgattcaaaa
    24181 gagtttattg cagagattga ttctaactta aaaaatatag aaggaataaa gcaaataaat
    24241 aagtcaagta caaatgttga tttaataaag aagttttatg atgaaaaaga tataaagaaa
    24301 atctatactg ctagattaga ctttggtagt agatctgatg taaacgaata tatttctttg
    24361 ggagtagtat cagcaaaaga aaatatgcca atactgattt gtagtgataa cttaagtcgt
    24421 gcacaagata aattcttgaa agatagcaat ataaatgatg tagttgaagt tgggtataca
    24481 gtaggtgatt atagtctatt taagagcata tttaatctaa cattcttatc ttgtatagta
    24541 ttaatactat tattactatt gattacattt agggcactta gatatgagtc gaaatagttt
    24601 ttgatttata aggaagcttt tcataggtta aatttactta attagaataa tgtttataag
    24661 cagttttaaa agttctactt ttagagttta aattagataa ggagaaagaa gatgtcaaaa
    24721 acagctaaag cagcattgtg gattatggca gccactatgt tttcaaaagt attaggtttc
    24781 cttagagaac ttgtacttgc aaatttctat gggacaggta tgtatgcaga cgtatttgta
    24841 ttaacattaa atatacctgg tttaatcata gcagtcatag gctctgcagt tgctacaact
    24901 tatataccta tgtactttga gacaaagaaa agactcggag atgaaggtgc cttaaaattt
    24961 actaataatg ttttaaatat atgctatata atggctatag taatagctat tattggtctt
    25021 ttatttacag agcaatttgt tacagtattt gcagcaggat ttagaaacga ccctgctaag
    25081 ttccaagcag caatattatt tactaaaata atgatttcag gagttttatt cctgagtgga
    25141 agtaagatat ttagttcgtt tttacaggtg aatgacagtt ttgtaattcc tgggcttata
    25201 ggaatcccat ataatattat aataatagca gcaatagcac taagtgcagg taaaaatgta
    25261 tggatactgc cagcaggagc attattggct atggcgagtc agctattgtt tcaactgcca
    25321 tttgcgttta agaagtccta caagtataag ccatatataa atttaaagga tgagtctata
    25381 aaagagttag tcaacctagt attgcctatg ttggtaggag tagctgttgg acagttaaat
    25441 atatttgttg accgattatt ggcaaccact ttgggtgatg gaaagttgtc tgctcttaac
    25501 tatgcaaata ggctaaatga gtttgttatg gcattatttg ttacatctat aataacagtt
    25561 atatatccta aactagcaaa aatgtctggt aaagataata aagaaggatt tataagcact
    25621 attgtaaaat cttcaaattg tattatattg gtggtgcttc ctatatctat aggagctatt
    25681 atattagcag agcctcttgt tagaatatta ttccaaaggg gtaaatttga tgcgttatca
    25741 acagacctta catctatagc gcttagatta tattcactag gtttattggc ttgtggagta
    25801 agagatgtct tatatagggc attttactct ctttcagata caaaaacacc aatgataaat
    25861 ggaagtatag ctttaataat aaatatagtt cttaatttaa tattgataag accattgggt
    25921 catgcaggta ttgctatatc aactagtaca tcaaacataa ttacagttat attattattt
    25981 atatctctta aaaagaaaaa tggatatttt ggaggggata aaattataaa gactggtcta
    26041 aaaagtttgg tagcatctgg tgtgatggca gtagctactt tattgatata taataatcta
    26101 tatgcattta tgggttcagg aacaattaaa gaaattatat cagttggagc tggagtatta
    26161 ggtggagctt ctgtatatac tgtattgata gttttattta aggtagaaga gatggattta
    26221 gcttttgaat ttttaagaaa aggaaaacaa aaactactta gaagatagat aattaccttg
    26281 aaattttaaa ttagagtcag aaaggatgaa aatatggatt ataagaataa ttatgagatg
    26341 tggttaaatt ctccttattt tgatgaacaa acgaaaaatg agctattaag tataaaagat
    26401 gatgaaaaag aaatacaaga tagattttat aaaaatttag agtttggaac aggtggttta
    26461 agaggtataa taggagcggg aactaataga atcaatattt atactgttag acgtgcgaca
    26521 ctgggcgttt taaattatat catgaaaact caaggagaag aaggtaagca aaagggaata
    26581 gttatagcac atgatagtag atacatgtct agggagtttt gtatagaagt agcaaagact
    26641 ttaagtgctt atggtgtaaa ggcttatatt tttgaagaat taaagcctac accagaactt
    26701 tcttttgctg ttagatattt aaagtgtgct atgggaatag taataacagc aagtcataat
    26761 cctaaagaat acaatggata taaagtatat gactcagatg gtggtcaaat ctgtatagat
    26821 atggcaaatg atataatagc agaagttaat aagattgatg attacagtac tattaaaagt
    26881 atagattttg aagaagcttt atctaaaaat ttaataacta tattagataa tgaagtagat
    26941 gatgagttta taaaagctgt taagaaacaa gttttaagac aaaatataat agatgaatac
    27001 gggaaaaaat taaaaataat atatacacct attcatggta caggaaataa gccagtaaga
    27061 aaagtcttaa atgaatgtgg ttttgaaaat gtaatggtag ttaaggagca agaattgcca
    27121 gattctaatt tttcaacagt aaagtatcct aatcctgaag aaaagtcagt gtttaatata
    27181 gctattgaaa tggcaaagaa taatggcact gatttgataa taggaacaga ccctgattgt
    27241 gatagagtag gtatcgttgt aaaagattca agtggtgaat atgtagtctt aaatggaaat
    27301 caagtcggtt cacttttagt tagatatata ttagagagtt tagttgaaga aaataaactt
    27361 cctaaaaaca atcctacaat aataaaaact atagttacat cagaactagg tgcaaaaata
    27421 gcaaaggctt ataatgtaga ttgtttaaat actttaacag gatttaaatt tataggagaa
    27481 aaaataaaag cgtttgaaga aagcaatgat agaagtttta taatgggata tgaggaaagc
    27541 tatggttact taattggaac tcatgctaga gataaggatg gtgttgtatc ttcacttatg
    27601 atatgtgaaa tggcagcata ctattcttca aaaggtatga acttgtatga agctttgata
    27661 gatacatata ataaatttgg atactacaaa gaggacttaa agtcagtaac tttaaaaggc
    27721 atagatggaa taaaaaaaat aaaagagatg atgctttact ttagaagtgt taaaatagat
    27781 aatgtggctg atgtaaaagt agataaaatt ttagactata aagatggtgt tgatgattta
    27841 cctaagtcag atgtacttaa atttttactt gaagatggct cttggatagc tataagacct
    27901 tcaggtacag aacctaaaat taaattttac tttggagcaa attcagacaa tcaagaagat
    27961 gtagaattta agttgaacaa tttaatatct tatatattaa atgtagtgga ttctatataa
    28021 aaagctaagg ggagataaac aatgaaagta tacaatgtca taatggctgg aggaggagga
    28081 actcgtttct ggccacttag tagacaagaa gtacctaaac agcttataaa tttaagtgga
    28141 gaagatgctt taataaacga aactataaac agaatagatt ctctagcaaa aaaagatgat
    28201 ttatttatag taaccaatga gaagcaattg gaagctttaa aggatatagt aaaagataaa
    28261 tgtttggata gtaatatatt gccagagcca tgtgccagaa atacagcagc agctataggc
    28321 tttgcagcat ttaacataat gaaaaaatat ggtgatggtg ttatgtgtgt atatccagct
    28381 gaccattata taaaagatga aaaagaattt aaatctattt tggaaaaagc tatctatata
    28441 gcagaaaata atgataaact agtaactatt gggataactc ctacatttcc atcaacagga
    28501 tatggataca taaattttaa tagagaaaat actatagaag atgttgcata tgaggtagtg
    28561 gagtttgtag aaaaaccaaa ctatgaaatt gctaaagaat atgtaaactc taaaaagtat
    28621 gtatggaata gtggaatgtt cgtatggaag gtatctaaaa tactagaaga ttttaagaga
    28681 tacttgccaa aagtatatga aaaattagaa gatataagta aatacttagg aacaaaagaa
    28741 gaaatggaaa aaataaaaga aatataccca actatacaat caatctctat agattatggt
    28801 attatggaaa gaagtaatga tgttatagta gttcctggtg attttggatg gaatgatgtt
    28861 ggttcttggg attctctagg tgcaatatat ccaactgatg atgaaggtaa tatcaaaaga
    28921 ggtgaaaata ttactataga tactaaaaat tcaattatat attcagatga caaattaata
    28981 tcaacaatag gtattagtga tttgatagta gtatctacaa atgatgcagt tatggtttgt
    29041 agaaaagata aagctcaaga tgtcaaaaaa atagtagagc agttaaaaga agaagataga
    29101 caagaatata tgtaggaggt gttcatttga ttcctaaaaa aatacattat gtatggtttg
    29161 gtggtccaaa aggaaatata gaaaatatat gtataaattc ttggaaagaa aagcttccag
    29221 aatatgagat agtagagtgg aatgaaaaaa actttgatat agagaaagaa ataaaaggaa
    29281 ataagttttt ggaagaatgt tataaaagaa aactttgggc attcatatct gattatacaa
    29341 gaataaaagt actctatgaa caaggtggag tttatatgga tacagatatg caaatattaa
    29401 aggatataac tcctctttta gaaaataata ggctagtctg tgggtatgaa gatgatagag
    29461 agtatataaa tggtgctata ataggtgtag aaaaaggaca tcctttttta aaagacttat
    29521 tggagtatta tgaaaaagaa gtacttactt cttcattgtt tacaatacca aagataatga
    29581 ctcatcttat ggaaaagaat tataagaaga ttgatccaaa taattatgaa gaaggaatac
    29641 gtgtttacga caaagaatat ttttatcctt ttggatttaa agaagacttt acaccagaat
    29701 gtataacaga aaacactttt gggatacatt ggtggggaaa aagttgggct aaaaagagaa
    29761 attatttctt agaaagcaaa cacttaacag gtgtaaataa gatatggaag tgttgtaaaa
    29821 tatttgcaag taatacttta cgaagctaaa agggagaaag taaaatgaag actttaaatg
    29881 atgatagaaa tattatgatt agaaaatatc tttatatatt tgttttgttt atcatattac
    29941 ttagaaagta tatgatatca tttattgacc caaatatgga tatagggatg attaaatcag
    30001 cgttatttta ttcttcaata ggaatactaa tgctactttt tttatttgat aagagaaaaa
    30061 gtataacaga aatggtacta gttggagttt gtgtcttact ttatttatta aatagggaag
    30121 gagctatatt attaatcgtt ttattagctg tatcagctaa gcaaatagat gataaattta
    30181 tagttaaaaa ttatttaata atatcggcat gttttttaat ggtagctata ttattattta
    30241 atttatttcc ttcattaata tttaatcagg aagtccacta tagatatata gaaaaaatag
    30301 atatgcttgt tacaagaatg gattttggac ttggtaatcc aaatagtgta ttttatcata
    30361 tggttactat atatgcagca tatatattct taagatataa agattataat aaatgggata
    30421 gaatactttt atttggttct gcattttttg tttatcaaac cacatatagt agaactggat
    30481 ttttcactat attagcagga ttaatatttg tagaaataat aagatggata gatataaaaa
    30541 aaataaaagg actaccaatg ctcctaaaga cattaccggt aatacttact ttatttagtg
    30601 taattattgg tacagtattt gataaaagca ctttattaaa tagattatta gcaagtagac
    30661 ctaagttctg gaatgtatac ttggctgaaa aggggaactt tctaaaacct tttggaaatt
    30721 catatagtcc tgctataaaa gcaactaatc cattagatag ttcttatgta tatataatta
    30781 gtgtactagg agtagttgct tgtatattat ttatgtattt gatgtataaa ggaatagaaa
    30841 gctttataga aaaagataaa aaagcatatt tagtagcttt atttatattt ttactatact
    30901 cttttgcaga aaatttatta ttagaagctt catttagttt tgcagtagta ttactaataa
    30961 aagaagtgat attaaatgat aaaagggaaa tagatttgtg gaagatgaaa agtaggaggt
    31021 agtaatgtta atatcattaa taatgccaac attaaataga tatgatgata tatacttact
    31081 tatggacagc ttagaaaatc aaacttacaa aaactttgaa cttatagtag tagaccaaaa
    31141 tgataatagc aaagttaaag aaatagttga taaatacatt gataagttag atataaagta
    31201 tataaaaagc tctaaaaaag gattgagtta taacagaaat gtaggcatag acaatgctgt
    31261 agggcaaatt ataggtttcc ctgatgatga ttgtgtctac gaaaatgata cattagaaaa
    31321 agttataaat ttctttaata aaaataaaga ttataaaata tacagttgca aaactatgga
    31381 ttcaaataaa gttgatgcat ttaagaaaat gtatgatgga acttgtgata tcacaagttc
    31441 caacgttttg gatactataa catccataac tttttttatt gattttgaag gtaaagacta
    31501 tacaagattt gatgaaaaat tgggtgttgg tggagagttt ggtgctggtg aagagataga
    31561 ttatgtttta aacttattga gtttaggttt taaaggaaaa tactttggaa atgatataat
    31621 ttaccatcct gcaaaaaaac attctaaatc taaagaaaag tatcaaaaag attataacta
    31681 tggaagaggc tttggagcgc tttgcaaaaa ggaaatagtc tatagaaaaa attataagtt
    31741 tgcaaaagtt atggtatcaa aacttgtaag aaatatagga ggtcttatat tgagttccaa
    31801 tagagattat catagtgcca ctataaaagg aagaattaat ggatttagac agtacaagtt
    31861 ataatgagga tggtgtttat ggacaaggtt aaatttttaa taaatatgct tttggctttt
    31921 tttatatatc catttaataa gcataagttt aatggtagag atatctggct tataggtgga
    31981 cattcagggg atatatacaa tgataattca aagttttttt atgagtatat gctaaaagaa
    32041 cataatgatg tagaaactta ttgggtagta aataaagaca gtaaagtatt tgataaaatt
    32101 ccaggcaaaa aattaataag aggaagtgta gaaaactatc tgtattatta caattcaaaa
    32161 gctatagtat tttcacatgc accatcagca gatatagcac catacaattt tgctgtacct
    32221 gttcttaatt attttcataa aaaaacgata aaagtgtttt taaatcatgg gactataagt
    32281 tttaaaaaaa gaaaacctat gaacaaaaag ttcaaaaata ttatagataa cctatataaa
    32341 agctataata tagttacagc aagttctgaa tttgaaagaa atgttatggt aaatgattgg
    32401 ggaatgttag atgactcagt ttatataatt ggaaatgcaa gatatgacaa tttaccaaca
    32461 aatgaagttg cacaaactcg agatatatta tatactccta catggagaga ttggataaaa
    32521 tttagttcag gaaaatttac ggatacagat tattttaaaa atataatgaa ttttttaaat
    32581 gatgacaaat taaataaaat attagatgag aaagatataa atgtaaaaat ttatatgcat
    32641 catcttatgc atgagtttat agatgatata aaagaaaata taacaggaaa acgaattgtg
    32701 tttttagata aaggggtaac tctagcaaat gaaatcagaa aatcagctgc aaatataact
    32761 gattattcaa gtgtagccat agactttttg tatatgaata gacctatctt gttttaccaa
    32821 ttcgatttgg atgaatatat ggaaaaagtt gattcatata tagatttaaa aagtgaaatg
    32881 tttgggtctt tggcttataa taatgatgaa gccgtgaata aacttattga tattattgaa
    32941 aataattttg aggttatgga taaccaaaaa aatgaaagaa ataagttttt cagatataat
    33001 gataataaga actgcaagag gatatatgat tgtgtattaa gtaaaattaa ataaatattt
    33061 tataaatgat gaggaaggta atatgaagaa gaatttagta tctataatta ctcccatgta
    33121 taattctgaa aaatttattg aagcaaccat aaaatcagta ttaaaccaaa cttatcaaga
    33181 atgggaaatg ttaattattg atgattgctc aacagataat agtcctaata tagtcaaatc
    33241 ttatatgcaa caggatagta gaataaaatg tataaagact gagactaata agggtgtctc
    33301 taatgctaga aatttagcac taagtaaggc aacaggacaa tttatagctt ttttagatag
    33361 tgatgaccaa tggaatagta gtaagttaga aaaacaagta aattttatgt tagaaaatga
    33421 ctatgtaatt tcatttactt catatgaact gatggatgaa aatgataaaa aattaaacaa
    33481 agtaataaaa gttccaccta atgtagatta tagaagatta ttaaaaggaa atatcttagg
    33541 atgtcttact gttgtgattg ataagtctaa attggatttt gaaataagaa tgagtggtgt
    33601 aagacatgaa gattatgttt tatggttatc gatattgaaa aaagggcata ttgctcatgg
    33661 aataaatgaa gttctagcat tatatagaaa atctagcaat tccctaagtg gtaataaaat
    33721 aaaagctgct atgtggactt ggaatatata tagaaatata gaaaaaatac ctttatacaa
    33781 agctatatac tactttatta attatggaat aaacggaatc aaaaaaagtt agacagagag
    33841 gaagatttaa ttaatgtata aatataaatt tactgtattt actccgacgt ataacagagc
    33901 tcatttactt gaaaatttgt acaatgattt aaaagctcaa acttatgatt tcaatgattt
    33961 tgaatggttg attgttgatg atggaagtag cgacagtact aaagagttag ttgaaaaatt
    34021 tatatcagaa aataaattaa atataagata tatatacaaa gaaaatggag gaaaacatac
    34081 tgcaataaat ctaggtgtaa aaaatgcaga tggagagcta tttttcattg tagatagtga
    34141 tgatggttta attaaagatt ctcttgaaat tgctaatgat gagtgggatt ctttagagaa
    34201 taaagaagga tttagtggag ttgttggact ttgtgtatat ccaagtggag atttgatagg
    34261 gacagaaatg cctgaagata agaaaatatg tcactttgca gacctatatt ttaagtatgg
    34321 cgttaaggga gataaaagca tagtatttgt aactgatgag cttataaaat ttccttttcc
    34381 agaaagaaaa gaagtgagat ttttaccaga aagtgtagta tggaatgaaa tgtctaaata
    34441 ctataaagtt atatgtgtaa ataaacctat gataataaga gattatttgg atgatggttt
    34501 gactaagaat atattaagta aaaatgcatt aagaggtaga gcattagagt ttttatattt
    34561 aataaatcaa aatacatatc cattaagtag atatccatat atgtggataa aaaattacat
    34621 aaatttagcc agatactcat tgttgtctga tagtcattat tttggtgaat taagaaaagt
    34681 atctgataaa ttgttgtatt tagcattatt cccattagga tattacaaat atattggaca
    34741 aagaaaatta gtatctaagt aaacttgttg gtatagtact gctagttgct atataaggag
    34801 agtaaaaata tgaatgagcc tttagtatcg ataattactc ctgtttataa ttcagaagag
    34861 tttttatcag agacgataaa gtcaatccaa aatcaaactt ataaaaattg gcagctttta
    34921 ttagtggatg attgttctaa ggacaattca agtgaaatta taaaaagttt tcgaaaagaa
    34981 gatgctagaa taaaatatat aaagcttgaa aaaaattctg gagctgcagt atctagaaat
    35041 gttggtatta agaatgcgga aggtcgattt attgcatttg tagatagtga tgatttatgg
    35101 gatagtagaa aattagagat tcagatagaa tatatgttaa aagaaaatgt aggtttttct
    35161 tttacatctt atagatatat gagacaagat gggtcaaaaa cgaataaggt tgcaagagct
    35221 cctaagaaaa ttgactatga aggattactt agaaatacta taataggatg ttctacagtg
    35281 gtcattgata aggagattgt aggagagttc agcatgcctt tggtaagaag aggacaagat
    35341 actgcaacct ggttacagtt acttaaaaag gaaaaatatg catatgggat tcaagaagat
    35401 ttagtgaatt acagattagt tggaaattct atatcaagta acaagataaa agcattaaaa
    35461 cgaacttgga atacttatag aaatgttgaa aatttaagtt taccaaaaag tctatatgta
    35521 ttttgtttct atgtttttaa tgccattaaa aaaagagtat aagttttata tacttggagg
    35581 taaaaaaatg aaaatagcta tagctgggac gggatatgta ggtttggtta caggtgtttg
    35641 tctagcagag gtaggcaatg aaaatgtagt ctgtgttgat gtagatgaac aaaaagttaa
    35701 atcaatgaaa cttggaatag cacctatata tgaagaaggc ctagaagaac ttatggttaa
    35761 aaattacaac agaggaagaa tagattacac tacagactat aaaaaagctt atgaagatgt
    35821 agatgtaata ttaatagctg taggtacacc tgagagaagt gatggttcag ccaacctaga
    35881 ttatataaag gcagttgcaa agcaaatagc tgaaactgtg acaaaagata ctctagtagt
    35941 aataaaatct acagttccaa ttggtacaaa tgaagagata gaagattata taaatagaaa
    36001 cctaaaaaat gatgtaaaag tagaacttgc atctaatcca gagtttttat cacaaggaac
    36061 agcagtaaaa gatactctac atgcttcaag aatcgttata ggtgtagaaa gtgaatgggc
    36121 tagagaaata ttagaggaaa tctataagcc ttttaatcaa cctataatag ttacaaatag
    36181 aaatagtgct gagatgataa aatacgcatc aaataacttc ttagctctta aaatatcatt
    36241 tatgaatgat attgcaaatc tttgtgaaat agcaggagct aacatagaag atgtagcttt
    36301 aggaatgagt tatgatgata gaataggaag taagttttta aaggcgggaa taggatatgg
    36361 tggttcttgc tttccaaaag acacaaaagc tcttcactgg ttatctgaac ataatggtta
    36421 tgaattaaaa acagtaaaag ctgcaataga agttaatgaa agtcaaaaac ttaaattagt
    36481 tagaaaggca tctaagttag tagagagctt tcaagatatg aaggttgctg ttttaggttt
    36541 gacttttaag ccagacactg atgatataag agaagcacca tctataccaa atataaaata
    36601 tttgctcgaa agaggggcaa gagttactgt atacgaccca attggtgtaa ataatactaa
    36661 gaaaatattt ggtgactcta tactttatgc tgattctgta gatgatgcga tagaagatgc
    36721 agagatatgt tttataatga cagaatggaa agatgtatta aattatgata tacataagta
    36781 taaggaaaag atgaaaaatc ctttagtcct tgatggaaga aattgttata aaattaaaga
    36841 tatggaagag ttaggaattg agtattattc gataggaagg taaatattat gaagactgtt
    36901 tgttatttag ctgatgggtc aaatcctcat actttaaaat ggtgtagttt ttttaaaaat
    36961 aaaggatatg acattcatgt aatctcttta aatggaggtc acatggaagg aataaaaatt
    37021 tataattttg gttctaatgt agaagaacta aaaaatgaaa atatttctaa aaaaacggga
    37081 tacttaggtt caataaagca gataaagaag ctagtaaatg aaataaagcc agatatattg
    37141 catgcacagt atgcaagtag ttatggattt ataggaagtc tacttgggta tcatccatat
    37201 attatttctg tttggggtac tgatatttat gatttcccta ataatggttt tatacaaaaa
    37261 caaattataa aacataactt tagaaaagca gactatatct tttcaaatag tagagatatg
    37321 gctaaagagg ctaataaata tacagctaaa catgtagatg taaccttttt tggagtagat
    37381 atggataggt ttaagcctat ggaagtagaa aaagaagacg cttttgtaat aggaattata
    37441 aagagtttag aaaaaaaata tggaatagaa tatttaatac aagcatttaa gatgcttaaa
    37501 gatgaatata aagataagaa aataattctt aaaataggtg gctctggaag tcagatggac
    37561 aacctaataa atttagctaa agaattgggt atagaaaatg atgttcagtt tttaggaaga
    37621 atatctccag aaaatgtaag caagactttt aattcttttg atgtaactgt atttccttct
    37681 ttaagagagg gatttggagt ggcagctata gaatcagaag catgtgaagt acctgttata
    37741 gttacaaatg taggaggaca tccagaatct gtatgggaaa atgaaactgg cttaattgta
    37801 gaaccaaaac aaccagaaga aataaaaaat gctataataa aactaatgga aaatgatgaa
    37861 cttagactta atatgggtaa gaaagggcgt caatttgtta gagaaaatta tgaggttaat
    37921 ttaaacttta atgatataga aaaaatttat gattctatat ttgataaata taaaaaataa
    37981 aatgaaaaaa tacagcaaaa gatagatgtt gttggctatg cttaggtgcg tagcttttgc
    38041 tgtttaaagg agggcttcta gttatgcgag aaagtataga tttagagaaa gaaagctttt
    38101 ttaataggct ttttaaaaaa tataaattta gacatttaac actattaatt ctagatattt
    38161 gtagcgtact agtagcgttt cgaatgtctt taagcttgac aggtaattta aatgcattta
    38221 ccactaatga tataataatt tcagtgtgta tatatatagt acttcatata gtatcattta
    38281 gattgtttaa gtgctacaac acattatgga gatatgcagg agaagaagaa attatatcta
    38341 tttttgtggc aactttagct tatttaattc cgatttatat aataaataaa ttattagggt
    38401 ttgattatcc tataatgttt tatgtattaa atacaatatt tattataatg tttacaagtg
    38461 gcgcaagaat agcctataga gctataagaa tagtcatgaa caagacatat tctagaggaa
    38521 aggtttcaaa tatccttata attggtgcag gagatgcagg agaaatggtt atacaggaac
    38581 taaaaagaaa tccagaactt aaaaaagtag cagtggctat aattgatgat gataaaaata
    38641 aaattggaag aataatccat aatgtgaaaa ttgtaggaac aacttcagat ataaaagatg
    38701 tggtagaaaa gtacaatgta gatgagataa tcttttcaat agcaaacata gagaaacgta
    38761 gaaaaaaaga tattattgat atatgtaaaa acactaactg taaaataaag acaataccag
    38821 gaatttacga aattatagat ggaaaagttg atataaaaca gattagagaa gtagagatag
    38881 aagacttgtt gggtagagag cctataaaaa caaatttaag agagataagt aattacattg
    38941 agggaaaagt aatcctaata actggaggag gaggctcaat tggttcagag ctttgtagac
    39001 agattgcagg atttaatcct aaagagctta ttatagttga taattatgaa aataatgctt
    39061 actcaataca acaagaatta cttagaaaat ataaaaataa attagatttg aagacagtaa
    39121 tagcatcaat aagagaagaa aaaagaatgg atgaaatatt taataaatat aaaccagaag
    39181 tggtatttca tgcagcagca cataaacatg ttcctcttat ggaatcgagc cctggcgaag
    39241 ctataaagaa taatatattt ggaactttaa acatagctgg cttgtcttca aaatatagag
    39301 ctaagaaatt tgtccttata tctacagata aggctgtaaa ccctactaac ataatgggag
    39361 ctactaaaag agctgctgaa atgattatac agactatgaa tgctgaaagc cagactgaat
    39421 ttgttgctgt tagatttgga aatgtgcttg gtagtaatgg tagtgtaatt ccacttttta
    39481 agaagcaaat tgaagatggc ggaccagtga cagttactca tccagatatt attagatatt
    39541 ttatgacaat accagaagca gtaggcttag ttatacaagc tggggctatg gctaaaggtg
    39601 gagaaatatt tgtgcttgat atgggagaac ctgtaagaat attggattta gcaaaaaact
    39661 taattaaatt cagtggattt gagccagatg ttgatataaa aattgaattt tctggtctta
    39721 gaccaggaga aaagttgtat gaagaactac ttatgtcaga agaaggtcta ttggatacag
    39781 agcataaaaa gatttttatt ggtagaccaa tagatgttga tagagaaaaa ataacaaaat
    39841 acttaaaact tttaagagaa attactaaca atgaagaggt tgaaaaaata gatggtatta
    39901 tgagggaatt agtaccaact tatattaaac cagaagatgc taatatcaaa gaaattgcaa
    39961 caactagaga aaagtagaat atatttctaa tttgtaacca gggggagcaa aaagaaacaa
    40021 atatatacta aaaagaaaca aaagattaca aaaagattac aaaaagatta caaaaaaggt
    40081 tgcaatttat tttgatgtaa gatagaatgt taattaggaa ttggaaacga aggaacaaaa
    40141 tgttaaattt tcgaaaggat taggtatttg agattatgat gaatattaaa aataaaaaac
    40201 atatattgaa aaaatttata gctatggtgt taatagcagg agttgtcaca gtagaagcag
    40261 gagcaataac ggctagtgca gcagagccaa ctaattcacc tatgagtgca acagtagacc
    40321 agtgtgattt tttaaatgta agaagtggag ctagtgcaaa tgatgcagta gtaggaaaga
    40381 taaacacagg agacaaagtt gaagttttag aattacattc aaatggatgg attaaaataa
    40441 aaagtgttga caatgttaca ggatgggtaa atggagatta tttaactatt caaggtggaa
    40501 atgtagatgc aaaggtacaa aatgttttaa acttagcatt taagcaacaa ggtaagccat
    40561 ataaatgggg agcaactgga ccaaattctt ttgattgttc tgggttcact tcttatgtct
    40621 ataaaaatgg agcaggagtt aatttaccaa gagtatcaag atcacaagca acagtaggaa
    40681 agaaagtatc aagagcagaa ttaaaaccag gagatttagt tttctttggt tcaggtggtt
    40741 caataaatca cgttggattg tatgtaggag attctaaatt catacattca ccacaaacag
    40801 gagatgtagt aaaagttact agcatggctc caggaactaa ttatgcaaaa agacttataa
    40861 ctgctacacg tgttttacaa taataataga tattgattta cataggattg aatattaaca
    40921 ttaaatatat aattacattt aatgttttac atagagattt aagagtttag taatattaaa
    40981 atagtgatga acgttataaa aacagcaaag aagataaatt tctttgctgt tttttttata
    41041 ataaattatt tcatattata atcaaatatc aaatataaat tttaactata ttattcaata
    41101 tttgacagat aatatgaatt ttagatatac ttaataagaa gtatattgta gaaaaaataa
    41161 atttaaaaaa ttaaggggga tgaaatgaaa aaaataagta tattagtatt atcattgata
    41221 atgacactta ctatgtgtag tgtaagttca tttgctgatt catcaaatga taaggaaatg
    41281 agagctgctt ggatatctac agtttataat ttagactggc ctaagactaa gaataatgaa
    41341 gccaagcaaa aaaaggaata cacagattta ttggacaaat taaaaagtgt aggaataaat
    41401 acagcagtgg ttcaagtaag accaaaatca gatgctttat ataaatcaaa tataaaccca
    41461 tggtctgaat atcttaccgg tacacaaggt aaagaccctg gatatgaccc attaccattt
    41521 ttaatagaag aagcacataa aagaggaatg gaatttcatg catggtttaa tccatataga
    41581 ataactatgg cagatgagag catagataaa ttgccagcaa accatccagc aaagaaaaat
    41641 ccaagctggg tagttaaaca tggaaataag tattactacg acccaggttt accagaagtt
    41701 agaaagtaca tagtggatag tatagcagaa gtagttcaaa attacgatat agatggagtt
    41761 cattttgatg attacttcta tccaggagta agtttcaatg atactgcaac ataccaaaaa
    41821 tatggaaaag gacaaaataa ggatgattgg agaagagaaa atgtaaatac tctacttaga
    41881 gatgtaaaag cgtctataaa gagtataaag cctaatgttg tatttggtgt aagcccagca
    41941 ggtatatgga gaaataagag tagtgaccca acaggttcag atacatcagg taatgaaagt
    42001 tatgtaggta catatgcaga tacaagagca tggataaaac aaggattgat tgactatgta
    42061 gttccacaac tttactggcc aattggtctt aaagcagcag attattctaa attagtggca
    42121 tggtgggcta atgaagtaaa aggaacaaat gtagacttat acataggaca aggtatatat
    42181 aagcaaggtc aatcgagtta tggtggacaa aatatagcaa aagaaatagt acaacaagta
    42241 acattaaata gaaagtatag tgaaataaaa ggtagtatgt atttctcagc taaagatata
    42301 gcaaatagta cttctataca aaaggattta aagagtttat attctagtag tgaagaacca
    42361 gttactccac catctaatgt taaagtggag aaattaagag gcgacgaaag atatgacaca
    42421 gcagtagcaa taagtaaaaa aggttgggct acaaattcag atacagtagt attagtaaat
    42481 gggtactcta tagttgatgg tataacatca acaccacttg ctacatcaaa tgatgctcct
    42541 atactattgg taaataagga taatatacct acatccacta agaatgagtt aaaaagactt
    42601 aatccaagta aagttatttt aattggagga aataactcta ttggagataa agttgagagt
    42661 gagataaaag atacattgtc aaatgtatca ataaatagag ttggtggttc agatagatat
    42721 agtacatctt taatgatagc aaaagaatta gtaaaaacta atccagtaga aaaactatat
    42781 ataacaagtg gtacaggtga agcagattct ctttctatag cttcaaaagc aggagaagaa
    42841 aagcaaccaa tagtattagt atcaaaagat aatgtaagtg atgaagttta caattggata
    42901 tcagatttaa aagtaaaaga tgcttatttt ataggtggta atctaagtat atctgattca
    42961 gtaataaata agctggataa ggtcattaca aatgatgtat ctaaaaatag aatagctgga
    43021 gaaaatagag aagaaacaaa tggaaaagta atacaaaaat tctatccaaa tgctgaatat
    43081 tcatcaatgt ttgtaagtaa aagtaatcaa ttggtagatg cattaacatc aggtccttta
    43141 gcagctaaat taaaatcacc agtagttatg cttggaaata gtgtaacatc tgctcagaaa
    43201 actgctttag agcctaagaa aactactcta gtatacgaag ctggagatgg tataaatcaa
    43261 aacacattaa acactttctt aaacttagtt aagtaataaa aaagttaatt taaaatacag
    43321 agtattttat aaatgtagat taaaatgaaa attatcatga taaattagaa aataaaaaag
    43381 aactatatgc attttgtaat caagtgtaca cagcaacttg aaaataatta tgcgatatag
    43441 ttctttttta gtaattaatc ttatactttt taataaactt tatgttgaat tttttattgt
    43501 ttaaactcta tgtcattaaa tataaaatcg tgtaatatgt ctaaagtatc tgggtcaaat
    43561 ctaagaaccc atccagcttt tccatatata ccacctgtac tatgaatttc atcatcaata
    43621 ggaaattcaa attgcttaat atttaagtcg cccattttta aaacttgagc tcctaaagaa
    43681 agtattgcat taggcttcat gttagtttta acatatggaa gaactgcatc taataaacct
    43741 ggatatttag taacaggtaa agtttccgtt ttcttgatta tagcttgtat aatctgtctc
    43801 tgtctgccat ctctagcaaa ggctgtatcg ttgtgtctga tacgtgcaaa agatagtgcc
    43861 tgatatccat ttagagtctg ctttccagag tttctaatgt attgtatgct acctttatca
    43921 tcacttttat tccatttata agtttcagga ataaatttat ttagttctcg tatttctcct
    43981 ttttcaacag taacctcaac gccaccaata gcatcaatta tatacataaa tgattcgaaa
    44041 ttaacacaag cataattttg aatatcaata ttaaaattct cttcaattgt ttgtattaat
    44101 aaatcagctt gtccataagc ataagcatga gtaagttttt gtttaccatg accagggatg
    44161 tctacatagc tatcacgagc taatgatgta agtttgatat cattgtgttt gttatcaata
    44221 gtaagtatca tcatagcatc tgaccttgaa gaatcttcat ttggtctagc atctgttccc
    44281 ataagtagta tgttaattat cccatcttca tttttatggt cattgttatc caataaatca
    44341 ctacttatgc tcgagtcatg aatagcagat aatttataat aaaaatatcc atagacactt
    44401 atagggaata ttactaccaa gaaagccagt agtataacaa atttctttaa ttttgacaaa
    44461 agtacccctt ctttcttctt tttcctgtat attttttaat agcatacact taattatatt
    44521 aaagtattga gatatattca atacttgttt cagttacaaa aaaaagacaa tgatataatt
    44581 tataagaaaa tttatcgacc tatatatata gttaaaagta tatataatat attttttaaa
    44641 agtaatttat attttaaaat aaaaacacac cccataaata caaagtaatt tgcatttaag
    44701 aggtatgtat ttatcatcaa attattggtt tgttttggaa tttctaatct tcaaccataa
    44761 tatctttaaa tatgaaatca tgcattgcat ctagttcata ttcctcaaaa ggtattacat
    44821 agcctgcatt acctattttt ctaccatttt cagtagaaag aggaaactcc atagatttca
    44881 aatttaaatt tcctatactt aaaagttctt ttcctaaaga tattatttca ttaggattca
    44941 tattagtttt tacatacgga agtattgtgt taactagatt aggatattta gtgactggta
    45001 aatccttaac accatttatt aaactctgta taacacttct ttgtcttcta tctctttcat
    45061 ctgtactatc attttttctt atacgagaaa atgcaagtgt ctgatatcca tttaattttt
    45121 gctcaccaga atttcttata tatttaagag aacctttatt gtcattttta ttccatttat
    45181 aagtttcagg aataaattta tttaattctc ttatttcact cttatcaaca gtaacagtaa
    45241 ctccacctaa agcatcaact atatccataa aagagaaaaa gtcaactacg gcgtagtttt
    45301 gtatatcaag ttggaagttt tcttctatag tttctattaa taagttagct tgtccatata
    45361 cgtaggcatg tgttaatttt tgttctccac gtcctggtat attaacataa gtatctctat
    45421 ttaatgaagt tagcttaaga cttttatttt tattatcaat agtaagtatc atcatggcat
    45481 cagaacgaga aacttcttct cctggtcttg catctgtacc taacaataat atgtttgtga
    45541 tattttcttc gtttttatag tcattactac taagcgcctc tgtatttata ctatcatctt
    45601 gtatagtttt taatttagta aaaacatatc catatatact aacaggaaat gctataacta
    45661 aaagggctag aaatataacg aactttttga gtcctgacaa taatatcccc tactttctaa
    45721 attttttaat tacacatagt taattatatt aaaaatttgt tacataagca ataaaaaaca
    45781 caataaatta gcataagttt gtcataatat aattattttt atagcatttt atagaagaaa
    45841 gtgtgtagtt attattgatt ttattggaat ataattgtat gaagacttaa atttttataa
    45901 actgatgtgt atattgaaaa aaatattttc ctgaatgtag ttatagcatc ttatgaaagg
    45961 tgcaaattgt aatttaaaat ttttagtgta taataagaat tgaaaattca aaccgataaa
    46021 aattaataaa aaataattat aaattaataa tttgggggag gaaatgtatg ataaaattaa
    46081 tagcaacaga tttagatgga actttgttag atgaaaagag cgaaataaat ccagagtttt
    46141 ataaagtatt taaaaaatta agagagagag ggataatgtt ttctgctgct agtggcaggc
    46201 agtatcaaaa tcttataaaa aaatttgaag atataaaaga tgatatgatg tttatatcag
    46261 aaaatggaac actagtagta tataaaggaa aagaaatatt atcaaatcct ttaaataaag
    46321 aattagtaaa tgaaatcata gagacaacaa gaagtataaa agggaaaaaa attgtaatga
    46381 gtgggaaaaa atacgcttat atagaaagca aagatgaagc gtttatacaa gaggtcagta
    46441 cttattatgc aaagtttaaa attgtagaag atttgacgaa agtagaagga gacatattga
    46501 agatagctgt atttgacttc aaaggtgcag aacataataa taatatctac tttgaaaagt
    46561 tttctgatag agctcaagta tgtatttctg gagtggagtg gcttgattta actgcaaaag
    46621 gtgcaaataa agggagtgcc ataaaaaaag tacaaaaaat gttagatata aaatatgaag
    46681 aaactatggt atttggtgac cagttaaatg atgtggaaat gatgaaaagt gcctatcata
    46741 gttatgccat ggaaaatgca aatgaacatt tgaaacaaat tgctagattt agagcaaaaa
    46801 gaaatactga aaatggcgtt gtagataaga taaaagaggt tataaaaatt ggatagtcat
    46861 atgtatagat gaaaaagatt attttgaaga aatcaaaaaa atatcaatgt aattttgata
    46921 aataagttta tttatgcgaa aattacattg atatttaata aacatcaata atagatattt
    46981 atttttttat gatattcagt attttgtttt ctatttgagt tgcattttca gcagaaatta
    47041 aataaacata tctacctgcc ttctcaatta tagtattatt tgctatttca gaattgattt
    47101 tttctccatg tccttctcca aaaggtgctt gtatcatatc ttttttataa ttttctagag
    47161 ttttatagat tttatctacc tcgtcagttt ttataacgat aatatcttct agagataatt
    47221 tttcagaaga attaattaca aaaccttgaa ttatgtcttc ctctacatca ttaaaatagt
    47281 taaaatcctt tgcatcaaag atttttgatt cctttataag taaatcagaa gattttaatg
    47341 ctttttttat ttttgatgta gaaacgtttt tgtaatcacc acttgaagaa caactaacca
    47401 ttcctaatga taagattatc gaaaaaaaca atattaaaat ttttttcatg ataaacctcc
    47461 aagtttttta aactctgtct taaattagtt tactacataa ttatataaaa ataaatgtat
    47521 ttaatgttac agttttgatt aataatgtaa tattttgata ataataccta ttgagaggtg
    47581 attagaaatg agaataccaa aacatgtagg aattataccg gatggaaata gaaggtgggc
    47641 aagtcaaaat ggtatgacaa aagataaagg atatgaaagt ggaatagacc ctggactaga
    47701 gtcttataga ttatgtagag atttaggctg tgaagaggtg actttttatg gatttacaac
    47761 tgataataca agacgtccat cagtgcagac aaaagctttt acaaaagcat gtattgatgc
    47821 tgcaaatata ttaatagatg aaggtgctgc tttattagtt gtaggaaata caaaatctcc
    47881 aatgtttcca gaagaattat taccatatac taatagaatt aaagccaaag aaggtcaaat
    47941 aaaagcaaat cttctggtaa attatggttg gtattgggac ttaaataata tatcaggagt
    48001 agaaaatgta aataaaaata atatacagga ttacatacag tcatttgatg tatccagact
    48061 agacttgata atcagatggg gtggaagaag gagattaagt ggtttccttc ctgtacaatc
    48121 aatttatgca gatttttatg ttatagataa ttattggcca gattttaaga gtgacgatat
    48181 aaaggacgca tttagttggt atgatacaca agatgtcact ttaggtggat aattaaaaat
    48241 attctgattt aaggttgtag agtgttttaa attattgaaa aaaaaacttc ttgatggtaa
    48301 aataacacta ataatatgta aaagtgtaaa aatttatacc aagaagggtg aagaaatgtc
    48361 aaaaggcaat aataacaata attcaagaaa caaatctaaa aagaccagtc atctgaatag
    48421 aaaaaagcga aaattaaata agaaaaagtt agcagtgttg atttgcttta cagttttatt
    48481 tttatttatt gcatttaagg ctactcaagg tgtagtagct ttggtaaaaa gtatggataa
    48541 aagtaataaa actaatcaac aacaaaatgt taactcagaa caatttgacc ttggtaatga
    48601 agaggaaaat aaaaagaaaa aatatactgt atttatagac ccaggtcatg gaggcaatga
    48661 taaaggaact gaaagcaaga ccagtaatag atatgaaaaa gacctaaatc tacaaattgc
    48721 aaaaaaatta gcaaataaat tatctaaaca aaaggatatt caagtagtag tatccagaac
    48781 tgatgataca tatatatcat taaaggatag agctatctta gcaaataata gttctgctga
    48841 tgtgcttgtt tctattcatt taaatgcaga gaaaaatggt aatacagcaa caggtataga
    48901 aacttggtat aggaataaag ctacagatgg ttcaaaagaa cttgcacaga cagtacaaag
    48961 tactatagta tcctatgtta aagttagaga taggggaata gttgaaaata actttgaagt
    49021 acttagagaa tcaaatatgc ctgctatatt aatagagtgt ggttttttaa caacaccttc
    49081 agaggaacaa aaaataataa atgaaaaata tcaagaccaa cttgcggaag gaattgttca
    49141 aggtgtactt tcatacctag attctaaagg gaataagtaa gttaacttta ctttaatgtg
    49201 aggataaatt taaaagttta actgtgtaaa ttgtattaac tttatttcgt aatgttgcaa
    49261 acattgtttg aatttagaaa ctatgaaatt agaaattatt ttatctatat ctaatttcat
    49321 agtttttttt gcaaaaaatt tatagttata aaattttaaa aaataaattt agtataatgt
    49381 aatgtagtta tttatatgtg attttaactt gcattgattt gctatcaatt gtgctttata
    49441 attagtatat ataaagttta actgtaagat aatttaaaaa ataggggaat ttatatgaat
    49501 aaaaatagca tgacaagaat ttacagttta aataaaataa tttttattat aattggaatt
    49561 ttaggaatag ttttactcac aagacatatt gaggtagata ttaaagtttt aattttaatt
    49621 ttattaacct tgtttagtat aaatgtattt atttcatatc ttaaaattaa gttgtatgag
    49681 gataaaatta atttaggatt gataaataat tcagataagt ttataaatat tactaaagat
    49741 gagaacttcc taaaacatgt tcaaaattat attatcagta atgaaaaaga aaactgtgta
    49801 atggcttgtt ttgatttatg tagactcaaa cttataaatg atatatatgg ttatgagcta
    49861 ggggatgaag tgttaaataa tattttaagt aacttaaaaa attattttgg aaaagaagct
    49921 atttatggaa agttaaaaag tgatgttttt gtattaataa taaagcttga aaatagggaa
    49981 cagaagattc cttatttagt aaatcttatt aagaataaaa ttgtgatact aagtcagatt
    50041 gacagtttta aaatggatat aaatattgag gcttctattg gaatttataa atttaacaat
    50101 aatgaaattg atataaaaaa agctatagat aatgctgata tggcaagact taaatcaaaa
    50161 ggactaaagc acatagagta tgtagaattt gataatgcta tggaagaaga aatacaatca
    50221 attatgaaaa tagagagaga tttattcttg gctattaaaa ataaagagtt tgtaattcac
    50281 tatcaaccta aagttgattc aagtacaggt aacattatag gttcagaggc attgataaga
    50341 tggttgcacc catcattagg catggttgga ccaaataagt ttatacctat agctgaaaaa
    50401 aatggtctga taaacaatat tggtagatgg ctaattcaag aagtttttat taccattaac
    50461 aagtggattt cagaaggtat aaatgtctta ccagtctcaa taaatctttc tagagtagaa
    50521 ctatataaaa atgatttagt tgattttttt aaactgatgt ttaatacata taatattcca
    50581 aaagaactta tagaattaga aattacagaa acgacagcac taagagatgt aaaatttata
    50641 agtgaaaggc tttatgagat taaatcttta ggtatgaata tatcattaga tgattttgga
    50701 gtaggtaatt caaattttat caaccttaag gggataccac tagatattat aaaaattgat
    50761 aggtcactta tattggatat agttacaaat acaaaaacaa agtttatggt gaaagcaatt
    50821 gttaaccttt cacatgattt aaacgtaact gttatatgtg aaggggtaga ggatatgcat
    50881 caggtcaaag tcttaagtga actgggatgt aatttcatac aaggttatgt attttttaaa
    50941 cctttggatg agatgaatta taaaaaactt cttactgacg gaagttatat aaatctgaaa
    51001 gatactcttt tagataaatg catgacagtt gaggaggagt aaggatgatt tcagaagatg
    51061 tagattattc aataagaatc ataagagcta tatttaataa tggagaagat aaaccaatag
    51121 atgctaaaat gatattaaaa agtgaagata taccaatact aacactatac agactgctta
    51181 gaaagctttg tgcaaacaat attcttactt ttaacaaaga agatggcaag acatacatgt
    51241 taaatgtgtc attggataca ataagtctaa gaactattgt agaagtaatt gatggaaaaa
    51301 tatatataaa taaatgtacg agatatgtat ctaattgcag taattgctta aaaggttgta
    51361 aagtaaatcg tgaattgcta gaaatagaaa aagaaattta taaactttta tcgagaaaat
    51421 ctataagaca aatactagaa taaaaaattt tcagctatga taataattgg aggttttcgg
    51481 ttatggatga tatatctcaa gacaattttc tactgtctaa agagtatgag aatagcttag
    51541 atgtagatac taaaaaagca agtggaatat attatactcc taaaataatt gtagattata
    51601 ttgtaaaaaa aactttaaaa aatcacgata taattaaaaa tccatatcca cgaatacttg
    51661 atatttcctg tgggtgtgga aattttcttt tagaagtata tgatatttta tatgacttat
    51721 ttgaggaaaa tatatatgaa ttgaaaaaga agtatgatga aaattattgg actgttgata
    51781 acatacaccg tcatatatta aactattgta tatatggtgc tgatattgat gaaaaagcta
    51841 taagtatatt aaaagatagc ttaacaaata aaaaggtagt aaatgattta gatgaatctg
    51901 atataaagat taatctattt tgttgtgata gtcttaaaaa gaaatggcga tataagtttg
    51961 attacatagt gggtaatcca ccctatattg gtcataaaaa acttgaaaag aaatataaaa
    52021 aatttctcct agaaaaatat agtgaagttt ataaggataa agctgactta tatttttgtt
    52081 tttataaaaa gattatagat attttaaagc aaggagggat tggcagtgtt ataactccaa
    52141 gatatttttt agaaagtcta tcaggtaaag atttaagaga atatattaaa tcaaatgtca
    52201 atgttcaaga aatagtggat tttttaggtg caaatatatt taaaaatata ggggtatcta
    52261 gttgtattct aacttttgat aagaaaaaaa caaaagagac atatatagat gtatttaaaa
    52321 tcaaaaatga ggatatatgt ataaataaat ttgaaacatt ggaagaactt ctaaagagta
    52381 gcaaatttga acattttaat ataaatcaga gattgctatc tgacgaatgg atacttgtaa
    52441 ataaagatga tgaaactttt tataataaga tacaagaaaa atgtaaatat agcttggaag
    52501 atatagcaat aagttttcaa ggaataatta cagggtgtga taaagcgttt attttaagta
    52561 aagatgatgt aaagttgaac cttgtagatg ataaattttt aaaatgttgg ataaaaagta
    52621 agaatataaa taaatatata gtagataaaa gtgaatatag gctaatatac tcaaatgata
    52681 tagataatga gaatacaaat aaaaggatac tagatgaaat tatagggcta tataaaacaa
    52741 aattagaaaa cagaagagaa tgtaaaagtg gaataaggaa atggtatgaa cttcaatggg
    52801 gtagagaaaa gcttttcttt gaaagaaaaa agataatgta tccttataaa tcaaatgaaa
    52861 atagatttgc tatagattat gataataatt tttcaagtgc agatgtatat tcttttttta
    52921 taaaagaaga gtatttagat aaattttcat atgaatatct agttggaatt ttaaattcca
    52981 gtgtttatga taaatacttt aaaataactg ctaaaaaaat gagtaaaaat atatatgatt
    53041 actatcctaa taaggttatg aagataagga tttttagaga taataattat gaagagatag
    53101 agaatttatc aaagcaaata atatcaattt tattaaataa gtctatagat aaaggaaaag
    53161 tagaaaaatt gcagataaaa atggataact tgataatgga ttctttaggt atataagcag
    53221 ttgtaagtat taaaaaatta taatctttta attgtttatt taaatttaga aataaaaagt
    53281 tagcc
//
LOCUS       DAMKNB010000020        50684 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.021, whole genome shotgun sequence.
ACCESSION   DAMKNB010000020 DAMKNB010000000
VERSION     DAMKNB010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 50684)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 50684)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..50684
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.021"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            complement(<1..1231)
                     /locus_tag="PC494_001341"
     CDS             complement(<1..1231)
                     /locus_tag="PC494_001341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrC family protein"
                     /protein_id="HDF3911846.1"
                     /translation="MSKNIYVKETYEWIRIGNGENELTEIEYEKLLKYLENNNDVLKS
                     NIIDIKYKKLRFINYVGIICFENVILEILPKLSLSDNLVKDREILLQMLSICNKIPIT
                     MNEKIRLSLKNYNLLNFFVMYFIESMQTQMKKGIYFEYINKIENLNVMRGKILLSTYA
                     KEKGISPMKIRCEYDEYSENNFLNQVLKKACISILCRINDNSIQGKIKKILSYFQNVD
                     LIYIDRKKLLDYKFYKNNDRFKDCYLLARLLLLNLSMDNSQNNQEAFSILFEINTLYE
                     EYIGILIKSIWDNSFRETYIQDKSKFLLKNEQTGKKNFNLRPDIVLYDLKNEYEIIID
                     TKWKAIEVDSNVFYRSSDIYQMYAYITAYENAKRCILLYPCIQKDKNYSSWKLSESFK
                     GKFIEAKTVRLDDIKNTK"
     gene            complement(1224..3158)
                     /locus_tag="PC494_001342"
     CDS             complement(1224..3158)
                     /locus_tag="PC494_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HDF3911847.1"
                     /translation="MSENIRGTEYWLMEEFFYQETDTPQIFREESIIALGFDIKINLK
                     KVFSMGKKSEKYINENCNDKDFIKKFMSIKKGDYFLYKAYQNIEEKVKCNVSIGIVEE
                     DFENGYELSHILGHTLPVKWMHNFDTVSNCKVYTSEFYKLNNNDISSYLEIIKSQDKK
                     LLRKRIEESENNKWYLKNYYYKNVDKCVDDEELFIQPINLEQLESLKNIKTDDYILLY
                     NSEKVICENDHTMKSLFGVCQVMEGFDKEKVSALEGGYFFPVRWIEYEKENIDGNAWV
                     IFENNSIVEKYVKRFTNKMPLNTILYGPPGTGKTYNTKQMVYNLVSETSLRNRYYTGY
                     LDYKNNVEFCTFHQSYGYEEFIEGLKSDGEGNFKPEDGILKDISIEACYNALKFEKKM
                     SFELEKDSLTLETIKDRKKKLVLENIEYSESFNFEESENYVLIIDEINRGNVSKIFGE
                     LITLLEDDKRLTKSNQTIVKLPYSKEKFSLPPNLYIVGTMNTSDKSIALLDIALRRRF
                     NFEEIMPDYDLLSIVDGIDIRKMLYTINKRIEFLYDRDHVIGQAYLLAVENINDIVVV
                     FRSKIIPLLQEYFYYDSEKVGLILGGIGRNEKDKYIVYKEKLIASELFKNNNASIMES
                     KVNYCIKQNISSEELKNIYE"
     gene            complement(3187..3909)
                     /locus_tag="PC494_001343"
     CDS             complement(3187..3909)
                     /locus_tag="PC494_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein"
                     /protein_id="HDF3911848.1"
                     /translation="MENFNKNAKIIGIGAEGINIINEVEEKIKANMDIEKININQEIE
                     KEYVRSLLDGVDILFLIYSSEDKHIRDIIKAVSYMSNERRVLSIGMDCSEKENKEDLE
                     LGREFKINNDSIFKFVDLMNIMVESISDSCMINIDITDLKEAIVGDKGIKYSFEEFED
                     TKSYSEIADILFDRMEYIGEEFISKKGIVFVEGSPEFSIMELNDLISNIQSKVEESYE
                     VIFSLYIKENLNGNIRVGLLYN"
     gene            complement(3959..4945)
                     /locus_tag="PC494_001344"
     CDS             complement(3959..4945)
                     /locus_tag="PC494_001344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WYL domain-containing protein"
                     /protein_id="HDF3911849.1"
                     /translation="MSKVKRLTDVWIYINDKQKFTIKELSEEFNLSAKTIQRYLKELN
                     KMGLPIQAEQGRNGGYRVLNNSYIPPVIFTEKEVMIILFALKSLQIYNYKLMEIEINS
                     IMRKVSYERKSSIKVGIENIKRYIGFVANDTNDGDFKSSNVTEFFRASSESLILNIKY
                     KCGNQILEKNVCPIGIYLNKGAWFSPAYDCKSDKIILVHIDNIIDIKRTGESKKIHIN
                     LEEWLHEVYNNLYGNSSTTKKFGEIIYLNVLLTKEGVSKIKDSSWNLDMELNEDGSGI
                     ISTFIKVEDIDCYASILFFIGNNAKVIEPKFLNKLLYDKANELRYFYEENMV"
     gene            complement(5002..5502)
                     /locus_tag="PC494_001345"
     CDS             complement(5002..5502)
                     /locus_tag="PC494_001345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HDF3911850.1"
                     /translation="MRKNSINIALTAAITAIYAVLTLSLGFISYGPIQFRVAEIMMLL
                     AFLDKGYIVGLTLGCFLANVIGPYGVPDIIFGTLATFISASMIYITRKLGKQNKSTLV
                     IASLWPTVINSIVVGLMLNVFFGLPLILSMIQVGFGEFVVVTIVGVPFFCFLMKKYKN
                     VINIKF"
     gene            complement(5788..6099)
                     /locus_tag="PC494_001346"
     CDS             complement(5788..6099)
                     /locus_tag="PC494_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3911851.1"
                     /translation="MAGNLNNMRAVNNFRGDKNILECLVSFEGRSISQRKVRVFFKEK
                     QNQIEIDFAEEEISKLVENVVLNTSYQEMLYDEIEKQLEIDCIGTWMILSKLKDGSRV
                     H"
     gene            complement(6239..8503)
                     /locus_tag="PC494_001347"
     CDS             complement(6239..8503)
                     /locus_tag="PC494_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-dependent oxidoreductase"
                     /protein_id="HDF3911852.1"
                     /translation="MNIVGKGIKKIDGMSITTGKPVYTDDLSAKDALVVKILRSPHAY
                     AKIKDIDTSKAEMVDGVECVLTYKDVPKSRFTLAGQTYPEPSPYDRLILEDVVRYVGD
                     EVAIVAAIDEKTAIKAMNLIKVKYEVLTPVLDFEEAIGNKTMVHDEDRHCNFDIGMQR
                     EKNIVSHHDYTKGDVEKVLSNCDVVIEETYYTQAQAHAMMETYRAYNYLDHMGRLVVV
                     SSTQIPFHVKRHLSRALEIPASKIRVIKPRIGGGFGGKQTACVEIFSAIVTLKTGKPA
                     KIIYDRKETFNCSTSRHAMRLKVRLGATNDGIIKAIDIKALSDTGAYGEHASTTIGLV
                     GEKTLPMYNKVEATRFIADVVYTNKMPAGALRGYGASQGCFAVESTINMLANKLKMDP
                     TDLRLKNVVTEGETTFAYGKTLNSVDLIKCINKGKELIGWNEKYPCKHLDNGKIRSVG
                     MAITMQGSGIQGLDKSSAEIKLNDCGDYTLMIGSTDMGTGSDTILAQMAAEVLDTSIE
                     NITVISADTDLVPYDPGSYASSTTYVTGMAVVKAAQDLREKIISAGATKLGVEKDEVE
                     FDGIKLTSKKGSTLLFDIAVDSTIGPDTNQLIGLASHGSPVSPPPFIAGFAETEIDTE
                     TGKVDLVNYVAVVDCGTVINKNLAKIQVEGGIVQGIGMSLFEEVRYTEKGSMDTNTFM
                     QYKIPARCDIGNVKVDFVETYEPTGPFGAKSVGEVVINTPLPAIQEAVFNGIGVRINT
                     LPITPEKVFMEMNK"
     gene            complement(8507..8956)
                     /locus_tag="PC494_001348"
     CDS             complement(8507..8956)
                     /locus_tag="PC494_001348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2Fe-2S iron-sulfur cluster binding
                     domain-containing protein"
                     /protein_id="HDF3911853.1"
                     /translation="MLVKININGKKKSVDIEPEEYLVDTLRKVGNLSVKRGCDTGCCG
                     LCTVLIDKKPTLSCATLTLRALDKEITTIEGLENEVKEFSEVLVKEGAEQCGFCSPGF
                     ILTVLAMKDELENPTDDEIKHYLTGNLCRCTGYMGQLRAIKTYLEVK"
     gene            complement(8956..9744)
                     /locus_tag="PC494_001349"
     CDS             complement(8956..9744)
                     /locus_tag="PC494_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD binding domain-containing protein"
                     /protein_id="HDF3911854.1"
                     /translation="MFTVMDIVQPDTVEEAYSILNKRKTNQVIGGSAFLRMGKKRIGT
                     GIELSKLNLDYIKEYEDYVEIGSMTTFRTLETSSIIKNNFGRIIEDSVKNIIGVQFRN
                     VVTVGATVFSKYGFSDLIVALLSLDTEVELYNIGRISLEEFLNRDYEKDLLIKIYIKK
                     TNKNASYKSLRNAKSDYPILNVSVSKHMEQFKLCVGARPQKATIAKQASEFLSNNEIN
                     EINIDKAVEIASEELTFGSNMRASREYRKAMSKVLLKRAIMEVI"
     gene            complement(9939..11207)
                     /locus_tag="PC494_001350"
     CDS             complement(9939..11207)
                     /locus_tag="PC494_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HDF3911855.1"
                     /translation="MEASIHTIASNNLLIIFAIVSITGIICSKLSEIIKVPDVVLYLL
                     VGILIGPSFLKFIDIRGFQIENQLILTFGSAFILYLGGKEISLKVLRNVKISVFLLAT
                     LGVVISAFIMQQVIGFTFGISAMTALLAGTIIASTDPATLVPIFNQVKIKDRVKQTVI
                     SESAFNDATGAILTSAVLAVILSNKFSLGENIYELGTMVIVGVLVGLITGILLLKLVN
                     DKPYGIFKDFAPIISVISVVVAYELSTKLGGSGYMSCFIVGIITGNKKNFKIWLSQKS
                     YDADFYVAETLGTICRMAIFIILGSQVNLAQLSKYFMPSVITVLVLMFIARPLCVLVC
                     TLVDREAKWSKSEILFMMWVRETGVIPAALCGIISAMKVPGYEVISSVVFMTILITLV
                     IQGSTTKLVAKKLGLLEEEVINISEKVSTF"
     gene            complement(11548..11709)
                     /locus_tag="PC494_001351"
     CDS             complement(11548..11709)
                     /locus_tag="PC494_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III"
                     /protein_id="HDF3911856.1"
                     /translation="MKQDKQNEKQSEISKIKQSNDNKLEIAQELHVSKNIGNMLGYRI
                     DKKKMNRPS"
     gene            complement(11858..12940)
                     /locus_tag="PC494_001352"
     CDS             complement(11858..12940)
                     /locus_tag="PC494_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flippase-like domain-containing protein"
                     /protein_id="HDF3911857.1"
                     /translation="MRKLSKREKDFIQYGFLLFLICITTYLVLTTLDIKLIPKIIRLV
                     NKTYIFLGILTIIVYMIIESIVTHLIINAVQKTKVKFIGIKMATMGFYYNLVTPFASG
                     SQPMQIYALTKYDVSLSKSVAIVTNKTVVFQSTVTVFCGILILLNKSLLMEQVHSVKV
                     LITFGMIMNVSMLLGGLLIVFSPKQVKMIAEVLINFLSKFKTFKFLDSKRDRINHYID
                     DYNYSIKIFIKNVRILVLSILLTVLQLIAYFSIVYCVYKASNLRGVSYVHIMTLQVFL
                     YMAISPIPTPGNVGANEVTFFTMFSNIIPKELLGYSVLLYSGFVYYFILIVSGLFTFG
                     THYTLNSWKKEDKVNSNLDKVIEKLN"
     gene            complement(13043..14638)
                     /locus_tag="PC494_001353"
     CDS             complement(13043..14638)
                     /locus_tag="PC494_001353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF3911858.1"
                     /translation="MSNLSILIKNNIINEFKLNALKKADGREKQKIMGMMLSVVIIAG
                     LLIFYVTSLSLSLVDILKQINQLEMLLIFGFGLSTLTTIVTSLYKTSSYLFQAKDLDL
                     LTSLPIKESTVLASKILMLVGANYLFSSICMIIPAVVYFLNSDVSITYFPYLILLFLA
                     LPLLPIVASSIIFLFIGQISSRIKYKNLVLIIGSIILMLLYTLLMSRLNSMSVEMLKN
                     SVSISETIRKVYPPIYYFVDALKTGSIVSFLAFIAISIIPFFMFVTLFAKKFKDINAK
                     MSEGYKSKNYEFKGQKTSRPSKALLKKEFKRYTSSFIYFLNSSAGLLFLIVGTILILL
                     FGADKVGELLKLNIDFNLIKIQLLGVFFFIIVMNCTTYCSISLEGKNLWILKSSPIDE
                     REIFWSKILMNFLLNAPLSILCLILVSIRLDFEIQFIIVSICLIGSFSMFVALMGLLS
                     NLLYPNLDWKNEVAVVKRSASMIVTMLVSLAYVIILGGIYVLLGISFLNIYIILASIL
                     TLILDFMIWRIISTKGVKIFKNL"
     gene            complement(14685..15392)
                     /locus_tag="PC494_001354"
     CDS             complement(14685..15392)
                     /locus_tag="PC494_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF3911859.1"
                     /translation="MLKVINVSKSYKNKKVVSSVSFDVNDGELFGFIGHNGAGKTTTI
                     KAIVGIHDFEEGEVLINSKSIKKQPVECKKEMAYIPDNPDLYESLTGIQYLNFIADIF
                     EVAKDKREELIKYYSNKFELNKALGDLISSYSHGMKQKLAIISALIHSPKILILDEPF
                     VGLDPKASFILKEIMREFCDKGGCIFFSTHVLEVAEKICDKIAIIKDGNIIAYGTTEE
                     VKGSNSLESIFMELIEK"
     gene            15645..16790
                     /locus_tag="PC494_001355"
     CDS             15645..16790
                     /locus_tag="PC494_001355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HDF3911860.1"
                     /translation="MNTFEQLKISSTLIDGLKKQDITSPTEVQSLVIGNIIQNKDLLI
                     NSQTGTGKTLAYLLPIFEKIDTSKRETQALILAPTHELVMQITNQVELLAKNAELSVT
                     SLALIGEVNIQKQIKNIKAVKPHIVIGSCGRVLDLIKQKKLKSHNIKTIVLDEVDNLL
                     NGKNITCIEDIIRTTLRDRQIIGCSASLTDSTIKICDKLMKEFEIIKTKEKSQINPNI
                     NHSYLLGEIRDKFTFLRKALAATNPKKAIVFVNNEKNIEVIVSKLNYHNYKAIGIFGN
                     MEKEDRKNAINKFKLGKAKILITTDLSARGLDIVDVSHVFNLDFPKSKNEYLHRCGRT
                     ARGNRSGNTISIITKKELDIIKDLQKEFNIVITPKTLQNGELIDIIK"
     gene            complement(16904..18280)
                     /locus_tag="PC494_001356"
     CDS             complement(16904..18280)
                     /locus_tag="PC494_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HDF3911861.1"
                     /translation="MQTTNSSTMQKLFPILTNKNVDMKKEIIAGVTTFLTMAYIIAVN
                     PNILSETGMPAGALVTGTCLAAAFGCILMGVVANLPFALASGMGLNAFFAYTVVLQMG
                     VPWEVALTAVFVEGIIFIVLSVSGVREAVVNAIPKNMKLAVTGGIGIFIALIGLVNSG
                     IVIGDQATLIKMGRFTPAVIITCVGLIIIAVLDKKRVKGSILFGIVVSSLLAWAFAFI
                     NPEYAQKLGIYLPGGLFKFESLAPIAGKIDLGYVLHPTNIGGFLVVVCTFLFVDFFDT
                     VGTLVGVCSKANMLDEKGNVPNVGRALLTDAVATTVGAGLGVSTVTTYVESSTGVIAG
                     GRTGWTAITVGILFLAAMFFSPVFIAIPSCATAPALIYVGYLMLGTVKDIEFDNITEG
                     VPAFVTIACMALTYSIGDGLTLGILTYVFVNIFYNIFGAKKAEDKKHVSVVMIVLAIL
                     FIIKLWLL"
     regulatory      complement(18374..18476)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            18726..20072
                     /locus_tag="PC494_001357"
     CDS             18726..20072
                     /locus_tag="PC494_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HDF3911862.1"
                     /translation="MKDLTTGHEGKSIFFFAMPMLIGSLFQQLYNTADSIIVGRFIGK
                     EAMAAVSGANPIMFLLVAALMGVSLGFSILVSQFYGSGDLKKVKATIDTTYILLFIGS
                     ILISILGIVFGGPMLKLMNTPESVFAQSKLYLTIIFSGILFSAGYNSVSAILRGLGDS
                     VTPLYFLIIATILNIVLDLTFIVVLRMGVEGVALATIMAQAVSFIISIIYLNKKHEVL
                     KFKIKGIVYDNKIFKDGLRLGLPSGVQQMLFSIGNMALQFLVNSYGTSAMAAFGAGLR
                     IENFISLPIMNLGSAVSTFVAQNIGAGENERVKKGIRESIKMTLVLAVTVIALILLFR
                     ENLIALFNTDKDVIKIGSSYLFIIGPFFLFIGTSFVLSSAMKGAGDSMFALISSIVSL
                     WLGRLPASYMLSKFFGTDGIWMGIPFGWTLGLIVTVIYYKKGHWKTKAIVNHRINE"
     gene            20150..21544
                     /locus_tag="PC494_001358"
     CDS             20150..21544
                     /locus_tag="PC494_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SLC13 family permease"
                     /protein_id="HDF3911863.1"
                     /translation="MGIILKPKQFYMTVIATIILYFSLNYSFNIKFSICLSFLTILIW
                     AVDSVEKTFVALFFVILAFIFNIAPIKVILQFLFTENFYIIILAYIITNAVTKTGVAK
                     IISEKLILNTVNTPKKMILLSYILGILLIFFIPQPFPRVILVSAFYKEFLKEQQITED
                     SKSILLFSIFTASTFTSMFFVNGDTLLNYVVLELGNCNINWGQWAFYMSVPTIITCFI
                     TYFLFIFVFKKELHSIKFISNENLEGNKLHFSYSNLKKEFNLLNKEQKHVFLCLGIMF
                     FMFLTQFIHNINTLIIMSICVLLLLLRKIVGFSTLKEINWKVLIFFIAAFSIGGVLKY
                     SGVVDIMGNYLIKFIPNSSEIISILFLITLTIILNICLGSAVTTSSVVIPLLGSLHIL
                     KENSVTLCLFVYIIVSIQYILPFHHATIMVGHGENLYNSKVIFKYGLTLIPLTYFIII
                     CITFPWWKFIGLEI"
     gene            complement(21666..22340)
                     /gene="fsa"
                     /locus_tag="PC494_001359"
     CDS             complement(21666..22340)
                     /gene="fsa"
                     /locus_tag="PC494_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HDF3911864.1"
                     /translation="MQLILDTGNVEEIKELCTCLPIDGVTTNPSIVSKEKKNFKQLIN
                     EIGEIIGEDMPIHAQVLSTKYEEILEEALYISSLRKNIYVKIPVTQDGLRAIKDLHRK
                     GIKITATAIFTAHQGFLAAKAGANYIAPYVNRLDNISGDGVAMVSELIKIIDTYKMDT
                     KVLAASFKNAQQVIELMQHGVHSVTVPYDICKSMMNHPLTDWSVDKFIEDWENTFGKG
                     SKTNNI"
     gene            22614..23378
                     /locus_tag="PC494_001360"
     CDS             22614..23378
                     /locus_tag="PC494_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HDF3911865.1"
                     /translation="MFAEERIQAILNILKKEGRVTVKELSSKFNVTEDCIRKDLKNIE
                     KISSIRRIYGGAVLARETLENQDTKDRKEINIPTKKIIAEKAFNLIEDRETIFLDIST
                     INILLAKLLAESNKKVTLVTNMLDILNVVTSKPNNLNIISTGGLLNLSLDGFVGTPTI
                     EFISKYKFDKTFMGSCGVDVFNSSLTTFEIEDGLTKKAIINSSKKVFIVMEDKKFKFD
                     GNFKFAHLEDISSIITEKTPTPDIVDILSEFNVNVL"
     gene            complement(23667..23888)
                     /locus_tag="PC494_001361"
     CDS             complement(23667..23888)
                     /locus_tag="PC494_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3911866.1"
                     /translation="MDRLKRDMKNMKEDLKEGVKKTAYVMKNTAEDLKDDAQGAMVNL
                     EMKKDEMMERYEQKKFSKELEKQMKNEMK"
     gene            complement(24289..25566)
                     /locus_tag="PC494_001362"
     CDS             complement(24289..25566)
                     /locus_tag="PC494_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="HDF3911867.1"
                     /translation="MRRIFDKWEKLSIKYKLFSITTSLLIALALIIYLILYFLLPSYY
                     HEYKIEYLQESLKSLVDSSIHFDTYTLEERLYYMAKDQNLAILLKDNQGKIVYGKNEV
                     VILRYSKYMINSLEDEYRTSIPIYTKDAKDGPYTLELVMPLQPIDEANEVIRKLMPYI
                     ISIAILIAIIGAYIYSIVITKPLINIIESEREQEYRRKDFVATISHELKTPITIISGQ
                     IEGMIYSVGKYKDRDTYLKKSYECTQELKDLVNEMIEVSKSEILEKDLKLVSINISEL
                     LNRLVKRQVFLIEEKHMKTILKIEENLEIKADQERITKAINNIINNAIKYSPEESELI
                     IRLYDKNKRISKKTSNQRVVLEIENTGVTIEKRYLEEIFNPFYRIEKSRSRKTGGSGL
                     GLYIVSQIFKSHGFDYSIKNKENSVVFTVEFKN"
     gene            complement(25550..26218)
                     /locus_tag="PC494_001363"
     CDS             complement(25550..26218)
                     /locus_tag="PC494_001363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF3911868.1"
                     /translation="MNSSILVIEDDSNIQELISEFLSAEGYQVDTANDGLEGIQKFKQ
                     GSYDLVILDIMMPNLDGYGVCKMIRKSSSVPIIFLTALNDEGDQLKGFDLECDDYITK
                     PFSFNLLIKRVEAILRRSNKTINDKFIVFEKLKLDLNTYIAEIDGEPIELTLKEFNIL
                     KALIEKYPQVITREGLLDSIWGYDYYGDTRIVDAHIKNIRKKISLPYIKTVKGIGYTL
                     EKDI"
     gene            complement(26378..28879)
                     /locus_tag="PC494_001364"
     CDS             complement(26378..28879)
                     /locus_tag="PC494_001364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper-translocating P-type ATPase"
                     /protein_id="HDF3911869.1"
                     /translation="MSSNKVVESYKITGMTCAACAKAVERVTKKMDGVYDQSVNIATE
                     KLKIEYDNSKVNFDDIKQVVEKAGYGIIKEESNKKIDMKIDGMTCAACAKAVERVVKK
                     LDGVESISVNIATDKANIDYDPSKVKLSQIKAAIEKAGYKPIEEVKNKVDVDEDKLRK
                     EREMKSLFVKFIVAIVFAVPLFYIAMGPMIIKPIGPWPLPEIINPMTNTFNYALIQLI
                     LVIPVMIAGYKFYINGFKSLFSLSPNMDSLVAIGTLAAFLYSLYTTLQIANGQIQGMH
                     HHQLYYESAGIIIALILLGKYLESKSKGKTSEAIKKLMGLQPKTAIVLVDGKEVETPI
                     EEVEIGDILLVKPGTKIPVDGVVIEGYTSVDESMLTGESIPVEKNVGSKVTGASINKN
                     GVIKFKAEKIGGDTALAQIIKLVEDAQGTKAPIAKLADTVSGYFVPIVIAIAVVASLL
                     WFLIGGKDIVFVLTIFISVLVIACPCALGLATPTAIMVGTGKGAENGILIKGGEALES
                     AHKVNTVIFDKTGTITEGKPKVTDIVLNNNVKEEYLIKIASSAEKGSEHPLGEAIVKY
                     GEEKNIKFEKVDNFKAIPGAGIQVTINDESILLGNRKLMNDNNIKLGDLEEKSNILAS
                     QGKTPMYIAVDGNLSGIIAVADVVKESSKKAIEILHDMGIKVAMVTGDNAKTANAIAN
                     QVGIDMVLAEVLPEDKSKEVEKLQNQGKFVAMVGDGINDAPALAKADIGIAIGSGTDV
                     AIESADIVLMKSDLIDVPTAIKLSHETIKNIKQNLFWAFGYNTIGIPVAAGILYVFGG
                     PLLNPMIAAAAMSLSSVSVVSNALRLKNFKAYKRD"
     gene            complement(29163..29354)
                     /locus_tag="PC494_001365"
     CDS             complement(29163..29354)
                     /locus_tag="PC494_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1450 domain-containing protein"
                     /protein_id="HDF3911870.1"
                     /translation="MIRVCPNCSNVDVNKLKTLVGEENVKTGCIGQCRAFKKEAVGII
                     DNELEIKETEAEFFEACKE"
     gene            complement(29502..29744)
                     /locus_tag="PC494_001366"
     CDS             complement(29502..29744)
                     /locus_tag="PC494_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3911871.1"
                     /translation="MLEVTKIIIKYFASESDTFVKEEVCNFEELLKWSHKFIEGKKIE
                     DVLYIKSKENYKVNVIKSLEIKELEIVRKQQIPPYM"
     gene            29956..31779
                     /gene="typA"
                     /locus_tag="PC494_001367"
     CDS             29956..31779
                     /gene="typA"
                     /locus_tag="PC494_001367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HDF3911872.1"
                     /translation="MSQKHKIINIAVIAHVDAGKSTLVDAFLSQSGVFRKNEVVKDCV
                     MDSNDLEKERGITIYSKNCAINYEDYKINIVDTPGHSDFSSEVERVMKTVDTVILLVD
                     ASEGPMPQTRFVLQKSLEFGLKPILFINKIDKKDQRAEEVVNEVFDLFVDLNATDEQC
                     EFPIIYGIAKQGIAKLEMDDDSEDLSPLFKTIVNHVEAYPNYDNEPLQFQISALAYDD
                     YVGRLGIGRIYKGTLKNNTQVAICREDSVVSKGKVSKLSVYEGLKQVEVDEATSGEIV
                     VIAGIPDISIGETICDLDSPLPMEMIKIEEPTLSMNFLVNDSPFVGKSGKFVTTRHLK
                     DRLEKELEVNVGLKVEPLDTTDGYKVSGRGELHLSILLENMRREGYEVGVSKPEVLMH
                     KEDGKLMEPIERVVVNCPEVYSGTIINELNMRKGMMESMSIEGDYVKIEFLAPTRGLL
                     GYRSEFINATRGEGTLVRSFEKFEEFKGEIPSRGNGVLIAQGPGVTMGYSLNALSDRA
                     VMFVDPGVEVYEGMIIGMNSRKDDMVVNPCKNKKMSNVRASGSDDAIKLSPPRIFTLE
                     EALEFIEDDELVEITPDSIRLRKRFLNEHDRLRYNKSRQGK"
     gene            complement(31869..32777)
                     /gene="trxB"
                     /locus_tag="PC494_001368"
     CDS             complement(31869..32777)
                     /gene="trxB"
                     /locus_tag="PC494_001368"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HDF3911873.1"
                     /translation="MVDIIVIGAGPAGLTSAIYAMRAGLSVTVFEKNIYGGQVASTSE
                     VENYPAVQKISGVEFSNNIYNQAVAQGVDIQFDEVEEINLEGKVKVVKTSSGEHKAKA
                     VILANGVERRKLGCAGEQEFTGRGVSYCATCDGAFFKDKEVAIVGGGNTALEDALFLA
                     NNCTKVYLIHRRDSFRGEEVLEKSVKARENIEILYSHGVEKIEGEKTVSKIEVKNLKT
                     EEKRTIDVSGIFIAIGLKPNNKMFENVLDLDEGGYIISDESCTTSVEGVYVAGDSRTK
                     FLRQIITAASDGAIAAVQAANYINVE"
     misc_binding    33579..33810
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            33918..35399
                     /locus_tag="PC494_001369"
     CDS             33918..35399
                     /locus_tag="PC494_001369"
                     /EC_number="4.2.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine synthase"
                     /protein_id="HDF3911874.1"
                     /translation="MYYSSTRGTEEKVTASQAIIKGISNDGGLYVPSEFPNVKNELIN
                     LVNLTYSQIAFFVLSKFLCDFTEDEIKNCIENAYDEKFDCSSIAPLNKVNDTYFLELY
                     HGPTLAFKDMALTIMPHLLKTSIKKDNLEKDVVILTATSGDTGKAALEGFKDIDKIKI
                     IVFFPEDGVSPVQKLQMKTQTGKNTYVVGIKGNFDDAQSGVKKIFSDKEFNQKLLDNN
                     YILSSANSINIGRLLPQVAYYFYSYMKLVSNSDINLNDKINFVVPTGNFGNILAGYYA
                     KQMGLPINKLICASNDNNVLYDFFKTGVYDKNRTLKLTTSPSMDILISSNLERLLFEI
                     SNRNTDIVNKLLSDLSDKGVYKISDDMEKNLASFYGEYSNEEEVKSTINNVFKNYNYL
                     IDTHTAVAYNCYEKYKKETSDNTKTVIVSTASPFKFSEDVLKSIDCDFKDLDDFAIID
                     RLSSISKIDIPKPIKNLKNAEILHKDIYEKDELKLAIKKFLKV"
     gene            35409..36302
                     /locus_tag="PC494_001370"
     CDS             35409..36302
                     /locus_tag="PC494_001370"
                     /EC_number="2.7.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine kinase"
                     /protein_id="HDF3911875.1"
                     /translation="MLEIIVPATSANIGPGFDCLGIALNIYNKFYVEEIESGLEIEGC
                     EDAYKNENNLVYTSMKYFFDRVKPEKIPAGIKIKIQSEVPICRGLGSSASCIVAGVIA
                     ANALSGANLDKNQLLNIASEIEGHPDNVAPAILGNMIVSVTDNENIHYDIIKIPEELK
                     FCAMIPNFKLSTEKARGVLPKEIPYSDGVFNVSRVALLISALLNKNFDLLKVACQDKL
                     HQDYRGTLIENYNDIVEKSEQLNSIGVFLSGAGPTIMSLIKENDDSFVDNMKNYLQKL
                     KSDWEIKELCCDSNGAVLNII"
     gene            36426..37487
                     /locus_tag="PC494_001371"
     CDS             36426..37487
                     /locus_tag="PC494_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015617764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitronate monooxygenase"
                     /protein_id="HDF3911876.1"
                     /translation="MIIKELIIRDLVAKVPIIQGGMGVGISRSSLAGAVAKLGGVGVI
                     SGVQIGYDEEDFETNTINANLRAIKKHISKAKEISNGGIIGINFMVAMKEYETYVKEA
                     VKAGVDLIISGAGLPNKLPSLVKGSNVKIAPIVSTAKAANVILKMWDRKEKTTADLIV
                     VEGPKAGGHLGYSNEELDNIDSIDYDKEFVEILKVANTYGEKFGRNIPVVAAGGITSS
                     SDVKKYIDMGASGVQVGTRFVATYECDAHENFKMAYINASEEDVHIVKSPVGLPGRAI
                     RNKFIEEVKINRPEIKKCYNCLIPCNPKETPYCISQALINAVKGDVENSLLFCGNDAY
                     KIDKLSTVEDVINELISEL"
     gene            complement(37642..38154)
                     /locus_tag="PC494_001372"
     CDS             complement(37642..38154)
                     /locus_tag="PC494_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase family protein"
                     /protein_id="HDF3911877.1"
                     /translation="MSDFKEILAEEIKNNPFGLIGKDWTLITAENEGKVNTMTASWGG
                     LGVMWGKDVAFVVIRPQRYTKEFIDNTDKFSLTFFDEDFRKELSYCGKVSGREEDKIS
                     QIGFNIEHLNDTPYFKESKMAIICKKMYSQKLEPQCFIAEGIDGRWYPQKDYHTLYIA
                     EITNVLVKED"
     gene            38674..39609
                     /locus_tag="PC494_001373"
     CDS             38674..39609
                     /locus_tag="PC494_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HDF3911878.1"
                     /translation="MIRYYKTIDSKLEKLSFFEDGCWINLVEPNHSEINEISNLLNID
                     VESIESALDEEERSRIDVEDNHTLILIDIPVDESDSNSSHYTTIPLGIILTEEAIVTV
                     CDAQTKILNDFIVGHIKDFFTFKKTRFLLQILHKNAAYYLHYLRKINKMTIIIEREIY
                     KSMKNKELVQLLELEKSLVYFSTSLKSNELVLNKMVRTAGIKKYPDDEDLLEDVIVEN
                     RQALDMAKIYGDILSRIMDAFSAIISNNQNNVMQILTVVTLIFSIPTIISGFFGMNVI
                     NMPFSNNPNGFWIILLITSIICIVITFFMSRNKLL"
     gene            complement(39701..41572)
                     /locus_tag="PC494_001374"
     CDS             complement(39701..41572)
                     /locus_tag="PC494_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sel1 repeat family protein"
                     /protein_id="HDF3911879.1"
                     /translation="MKNTKFSIKKIKNISNDPKVVHTKGALLEKMGKMESAIELYKSA
                     ALDNYVKSQYTLGNIYESKKQFKEAEKWYSMAYKSGSEDAAFDLGNMYYKLDGYEYAI
                     YWYEKIANLGYLQAQNNLGVCHFKMKDFVRCEKWLKTAADKNLGKACFNLGVLYTFLE
                     KDDEAYEYYKKGSVLLDDDAKYNLAILNGKKKDNKSTVSLYKQLYKSGHMKGCFNLGM
                     IMEINDNLEDAEKYYKKSADRDDVKSEYRLAYVYDRKEELGDAIYYYEKAIEKNHTLS
                     KYRLANLYNRENEIEKAKTYYKMAAEDDITEAKNNLAGIYFEEKDYENAIKYYEDAIA
                     VGCKSSLENLGDLYYQNQDIEKAISYYSRIPNNVSCQIKLGNIYEDLNNIEEAISWYK
                     KASENGDTRSSYRLGCIYESLGNTKNARKYFEMASSKNHMNARIHLGRIYFREGKLEE
                     SKMMFDTPANENNVYAQHMVGLIYDMFYKDYVNSKFWYEKARAQGCVESIYNLGQIYL
                     KLNDDAEAEKYYKEGIKYGSKKCEYMLAGLYYKKSLDMYISLANEEYDNCEEIVEGFP
                     NLNIDFDEVLIPPFKLQEEVIDEEEYVPIYILNIKESLDSMLEGLETEMIIDEEHDS"
     gene            41762..42688
                     /locus_tag="PC494_001375"
     CDS             41762..42688
                     /locus_tag="PC494_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AEC family transporter"
                     /protein_id="HDF3911880.1"
                     /translation="MNFSNIFIQVAVLFIIILVGYFVRKFNLLDDHCTSKLSTLTMTV
                     FLPSMIISSMQINFDSKMIQKILLLLFTSLIMYIVSIIIAFLLKYILKCNDKKDLGIY
                     QYIVVFSNVAFMGYPVIEAVLGHEAIFYTAIFNLPFNLFSFTLGIYLLSKGSTSRGFS
                     IKSLISPATIAIVIGLFLFVTGLRLPQFINEPLEMLGSITTPISMIIIGSLLANSSAL
                     DCFVNKKLYIVTFIRLLVLPVIVYFILKGWINDKMILAIPVVISSMPAAANTAIMANQ
                     YDSNITLASQCVFFTTLFSVISIPFISILLLS"
     gene            42827..42973
                     /locus_tag="PC494_001376"
     CDS             42827..42973
                     /locus_tag="PC494_001376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3911881.1"
                     /translation="MDMDLLFKIVFAIVAIGVSVKIIKTVASLAFKIALILLIILFVY
                     RMFL"
     gene            complement(43078..43602)
                     /locus_tag="PC494_001377"
     CDS             complement(43078..43602)
                     /locus_tag="PC494_001377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDF3911882.1"
                     /translation="MSKPIDITIRPIRREDAQAFNEIRRTYSVMRNTLALMSDRVDKT
                     EAMLASLGENDYMFVAETNNNGEKDVIGFAGLHVNSSPRLRHSAEIGISVAENYQGRG
                     VGKKLMEQLLDIADNWIMLTRVGLEVIVDNEKGLNLYKKLGFEIEGTKKYAVIRDGKF
                     EDVYIMGRYNKNLI"
     gene            complement(43655..43879)
                     /locus_tag="PC494_001378"
     CDS             complement(43655..43879)
                     /locus_tag="PC494_001378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3911883.1"
                     /translation="MIIKLTKDNFNFRFKQYEGMFFHAEVVEGMESIRYKITKDKEGT
                     ELKEFGSTHIKDNMIYVPQVEAYIDLNSIK"
     gene            44076..45200
                     /locus_tag="PC494_001379"
     CDS             44076..45200
                     /locus_tag="PC494_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3810 domain-containing protein"
                     /protein_id="HDF3911884.1"
                     /translation="MSKKTKYFSLILFPIALLLNFIASKVPNIVEKYYSQFIDKIIVQ
                     ILSKVSGIFPFSLYEITMYIIVISIFLFLCCTLSTIFNKKKKLNIYLKNSILNILSIV
                     SIVYFLFVVLWGINYNRIPLETTLINNYNLKNNTSIQSKQYSVKELTKLYKFLVIKAN
                     ETRKLTLQDKNGIVKSNTDYNGVINRAQLGYDNILDILPGVSGSYSKPKYIISSNLMC
                     YTGITGIYFPFTGEANVNIAIPDLYIPCTVEHEMAHQRGFASEDEANFIAYLTSIKHP
                     NIDFNYSGYILALNYTASALSKVDYNAYVDISAGISDSVRRDLKNESEFWQKYEGKIN
                     EISNEFNNSYLKANSVTEGTQSYGKMVDLLLTYYELYPYN"
     gene            complement(45674..46498)
                     /locus_tag="PC494_001380"
     CDS             complement(45674..46498)
                     /locus_tag="PC494_001380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3911885.1"
                     /translation="MRYKKISSLPILVVALLITGTTTTFSLSTTNSEKTNVYLANTVS
                     TVTKKVSDIQSSKGLVYNENIPLFINNSKIQYDDTPYHWPSNVISLTNSSEKAIMDYE
                     ITCLAYDKNGKPLELYWDAQNVAADGEVGSVGFSPAGVDYGIVTGISPVSPKSYSHTY
                     RKMQQSPPQDIISMFEKQQGKAWVENWLKEWKQMEKEYAKQNAIAPGKNQNDAFLLFD
                     KWKQSTGEHGVKYIISCVKQVTFNDGSVWKNSAYENWLKSFQGKEVSNSVLENYYK"
     gene            complement(46846..47901)
                     /gene="ispG"
                     /locus_tag="PC494_001381"
                     /gene_synonym="gcpE"
     CDS             complement(46846..47901)
                     /gene="ispG"
                     /locus_tag="PC494_001381"
                     /gene_synonym="gcpE"
                     /EC_number="1.17.7.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin-dependent
                     (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase"
                     /protein_id="HDF3911886.1"
                     /translation="MSYERRKTREVSVGTVKIGGENPISIQSMTNTDTRDADATIAQI
                     KRLEEAGCDIVRVAVPDIKAAKNIAKIKSSVNIPIIADIHFDYKLALEAIEQGVDGIR
                     INPGNIGSIERVKMVVEKCKERNLKIRIGVNGGSLEKELLKKYGSATAEALVESAMGH
                     IKILEDLDFHNIVISLKSSDIYKTVDAYELISKKVDYPLHIGITESGSVHKGTIKSSI
                     GVGALLLKGIGDTVRISLTGDPVEEVIVGKQILRSLGLLNDKIKVISCPTCGRCNIDL
                     ISVVNEVEEKIGSMEKNITVAIMGCAVNGPGEAREADIGIAGGKGEGLLFKKGEIVRM
                     IDGNKLVDELLEEIEKL"
     gene            complement(48083..49087)
                     /gene="rseP"
                     /locus_tag="PC494_001382"
     CDS             complement(48083..49087)
                     /gene="rseP"
                     /locus_tag="PC494_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HDF3911887.1"
                     /translation="MTIIAALILFSIIVLIHELGHFIFAKRSGIKVNEFSIGMGPKIY
                     SVKKDTEYSIRALPIGGYVSMEGEDEEQISPNSFGNKSILQRFSTIVAGPIFNIILAA
                     ILLVPVFLYIGSPTTKLGKIMPDTPAQAVGLQVGDKINKINGNSVKTWDEVANIINTS
                     SGGELKLSITRDGSDKVVNVTPKNNNGKYEIGIQPQREKDFLGSIVNACKTTVDMTKQ
                     MLTFLGQMITGRVPGGIGNAVAGPVGVIGMVSDAARTGIINVVYLAAVISLNLGIVNL
                     LPIPALDGWRILMLLLEAVRGGKKLDPNKEGMINVVGFGALMLFMLFITYKDILRLFQ
                     "
     gene            complement(49100..50254)
                     /locus_tag="PC494_001383"
     CDS             complement(49100..50254)
                     /locus_tag="PC494_001383"
                     /EC_number="1.1.1.267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxy-D-xylulose-5-phosphate reductoisomerase"
                     /protein_id="HDF3911888.1"
                     /translation="MKKISILGSTGSIGKQTLDVVRDNRDKFEIVAISANSNIELLLE
                     QIVEFKPKYVTVFEENKALKLKEMLPKNIEIEVLAGMEGLKIISSLDEVDVLLTAVVG
                     MIGLVPTLCAIKKGIDIALANKETLVTAGELVMKEAEKYNVNILPVDSEHSAIFQCLN
                     GENKKNIEKIILTASGGPFRGKKKGELANITKNEALKHPNWSMGRKISIDSSTLMNKG
                     LEVIEARWLFGVEQENIDVVVHPQSIIHSMVQYTDSSIIAQLGCPDMRLPIQYALTYP
                     DRMESSFERMNFSKFSTLTFEEPDLETFPCLKLAYECLKMGGTYSSVLNSANEVLVSE
                     FLEDKIGFYDIPYYIEKTLEVHSSISEPTLEEILETDRWSRAYVANLIKK"
     gene            complement(50418..50621)
                     /locus_tag="PC494_001384"
     CDS             complement(50418..50621)
                     /locus_tag="PC494_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF3911889.1"
                     /translation="MISYAPLWKLLIDRKIKKMEFVNISGISISVLGRLGNDKSVSMD
                     TMEKICLALDCKIEDVVEIKKSI"
BASE COUNT        17267 a         8151 c         5681 g        19585 t
ORIGIN      
        1 tttttgtgtt ttttatatca tctaacctca cagtttttgc ttctataaac ttacccttaa
       61 atgattctga taatttccag gaactataat tcttatcttt ttgaatacaa ggatataata
      121 atatacatct ttttgcattt tcatatgctg ttatatatgc atacatctgg tatatatcac
      181 ttgacctata aaaaacattt gaatctactt caatagcttt ccatttagtg tcaattataa
      241 tttcatattc attttttaag tcatataaaa ctatatccgg tcttaaatta aagtttttct
      301 tacctgtttg ttcatttttc aaaagaaatt tactcttatc ttgtatatat gtttctctaa
      361 atgaattgtc ccatatactt ttgattaaaa ttcctatata ttcttcatac aaagtattta
      421 tttcaaataa tatagaaaat gcctcttgat tattttgact attatccata gacaaattta
      481 aaagtagaag tctagctagt aaataacaat ctttaaatct atcattgttt ttataaaatt
      541 tataatccaa tagttttttt ctatctatat aaattaaatc tacattttga aaatagctta
      601 aaattttttt aatcttgcct tgaattgaat tgtcatttat tctacataaa atagatatac
      661 atgctttttt aagaacttga ttcaagaaat tattttcact atactcatca tattcacatc
      721 ttattttcat tggagaaatg cctttttctt ttgcatatgt acttaataat attttacccc
      781 tcataacatt taagttctct attttattta tatattcaaa ataaatacct tttttcatct
      841 gtgtttgcat actctcaatg aaatacataa caaaaaaatt taagagatta taatttttca
      901 aactcaatct tattttttca ttcattgtaa ttggaatttt attacatata gaaagcatct
      961 gtaatagtat ctctctatct tttacaagat tatcacttaa tgacaattta ggaagtattt
     1021 caagtattac attttcaaaa catatgatgc ctacatagtt tataaatcta agttttttgt
     1081 atttaatatc tattatatta ctttttaata catcattatt gttctctaga tacttaagca
     1141 atttttcata ttcaatttct gtaagctcat tttcaccatt acctatcctt atccattcat
     1201 aggtttcctt aacatatata tttttactca tatatatttt ttagctcctc actagatatg
     1261 ttttgtttta tacaatagtt aactttactc tccattattg aggcattatt atttttaaat
     1321 aactcagaag ctataagttt ttctttataa acaatgtatt tatctttttc atttcttcca
     1381 attcctccta aaatcaaacc tactttttct gaatcataat aaaaatactc ttgaagaagt
     1441 ggtattattt tacttctaaa tactactact atatcattaa tattttctac agcaagtaga
     1501 taagcttgtc caataacatg gtctctatca tataaaaact ctatcctttt attgattgta
     1561 tatagcattt ttctaatatc tataccatct acaatagaca ataaatcata atctggcata
     1621 atttcttcaa aattaaacct tcttcttaaa gctatatcta aaagtgctat tgatttatct
     1681 gatgtgttca tagttccaac tatatacaaa tttggaggta gagaaaattt ttcctttgaa
     1741 tatggtagtt tgacaatagt ttgatttgat ttagtaagtc ttttatcatc ttccaataat
     1801 gttattagct caccaaatat tttagataca ttccctctat taatttcatc tattattaaa
     1861 acatagtttt ctgattcttc aaaattaaaa ctctcactat attctatatt ttctaatact
     1921 aatttctttt tcctgtcttt tatagtttct aaagtcaagc tatctttttc caactcaaag
     1981 ctcatctttt tttcaaattt caatgcatta taacatgctt ctatagatat atcctttaat
     2041 atcccatctt ctggcttaaa attgccttca ccatcagact taagaccctc tataaattcc
     2101 tcatatccat atgattgatg aaatgtacaa aattctacat tgtttttata atctaagtaa
     2161 cctgtatagt atctgtttct tagactggtt tcacttacta gattgtaaac catctgtttt
     2221 gtattgtatg ttttaccagt tcctggtggt ccataaagta tagtatttaa tggcatttta
     2281 ttagtaaatc tttttacata cttttcaact atactattat tttcaaatat aacccatgca
     2341 tttccgtcta tattctcctt ttcatactct atccatctaa caggaaaaaa atatccaccc
     2401 tccaaagcac ttactttctc tttatcgaac ccttccataa cttgacatac gccaaataga
     2461 ctcttcattg tatggtcatt ttcacaaatt actttctcgc tattatacaa taaaatataa
     2521 tcatctgtct ttatattttt tagactttct aattgttcta gattaatggg ctgaataaat
     2581 aattcttcat catctacaca cttatctaca tttttataat aatagttttt taaataccat
     2641 ttattatttt cactttcttc tattcttttt ctcaataatt tcttatcttg tgacttaata
     2701 atttctaaat atgagctaat atcattatta tttaatttat aaaattcact tgtatatact
     2761 ttacaatttg aaactgtatc aaaattatgc atccatttta ctggtagtgt atgccctaaa
     2821 atatgactta attcatatcc attttcaaaa tcttcttcaa ctatgccaat agacacatta
     2881 catttaactt tttcttctat attttgatat gctttatata aaaaataatc tcctttttta
     2941 atcgacataa acttttttat aaaatcttta tcattacaat tctcattaat atacttttct
     3001 gattttttcc ccatactgaa tacttttttt aaatttattt ttatatcaaa tccaagtgca
     3061 attatgcttt cttctctaaa aatctgtggt gtgtctgttt cctgataaaa aaattcttcc
     3121 attaaccaat actctgtacc tcttatattt tcagacatat acactctcct taatatctaa
     3181 aatatactaa ttatacaata agcctactct aatatttcca tttaaatttt cctttatata
     3241 taaagaaaat attacttcat agctttcttc taccttgctc tgaatattac ttattaaatc
     3301 attcaattcc attatagaaa attctggact tccttcaaca aatacaattc ctttcttact
     3361 tataaattcc tcaccaatat attccatcct gtcaaataaa atgtcagcta tctcgctata
     3421 tgactttgta tcttcaaact cttcaaaaga atacttaatt cctttatctc ctacaatagc
     3481 ttcttttaaa tcagtaatat ctatatttat catgcaagaa tcagaaatag actctaccat
     3541 gatattcatt aaatcaacaa atttaaatat actatcatta ttgattttaa actctctccc
     3601 aagctctaaa tcttctttat tttctttctc tgaacaatcc attcctatag atagaactct
     3661 tctttcgttt gacatatatg aaacagcttt tataatatct ctaatatgtt tatcttcaga
     3721 tgaatatatc aaaaataata tatctacacc atctaaaaga cttctaacat attctttttc
     3781 aatctcttga tttatgttta ttttttctat atccatattt gcttttattt tttcttctac
     3841 ttcatttatt atattaatac cttcagctcc aataccaatt attttagcat tcttattaaa
     3901 attttccatt ataacgtata tctccttaat aattatttaa tttcaacatt tctaaatatt
     3961 ataccatatt ttcttcataa aaatatctta actcattggc cttatcataa agtagcttat
     4021 tcaaaaattt tggctctata accttagcat tatttccaat aaaaaataaa atcgaagcat
     4081 aacaatctat atcttcaacc tttatgaatg tactaattat tccactacca tcttcattta
     4141 gctccatatc taaattccaa gaactgtcct ttattttaga aacaccttct ttagttaata
     4201 atacatttag ataaataatt tcaccaaatt ttttagtagt tgaactattt ccatataaat
     4261 tgttatatac ttcatgtaac cattcttcca agtttatatg tattttttta ctttctcctg
     4321 ttctttttat atcaattata ttatctatat gaactaatat tattttatca cttttacaat
     4381 catatgctgg tgaaaaccat gctcccttat ttaaatatat acctataggg catacgtttt
     4441 tttccaaaat ctgattacca cacttatact taatatttaa aattagagat tctgaagaag
     4501 ctctaaaaaa ctcagttaca ttactactct taaaatctcc atcattagta tcattagcta
     4561 caaagccaat gtatctttta atattttcta tacctacttt tatactgctt ttacgttcat
     4621 aacttacttt tctcattata gaattaattt ctatttccat taacttataa ttataaatct
     4681 gaagtgactt aagtgcaaat agtataatca taacttcttt ttctgtaaat ataacaggag
     4741 gtatatagct attatttagc accctataac ctccatttct accttgttct gcttgaattg
     4801 gaagtcccat tttatttaat tcttttaaat atcgttgtat tgttttggct gaaagattaa
     4861 attcctctga caactctttt attgtaaact tttgcttatc attaatatat atccaaacat
     4921 cagtcaatct ttttaccttc gacaaataaa cacctctttt cactaataat actctcaatt
     4981 aattaaatta ctatacacta tttaaaattt aatattaatg acatttttat attttttcat
     5041 taaaaaacag aaaaatggta ctcctacaat tgttactact acaaattctc caaaacctac
     5101 ctgtatcata gatagaatta atggaagccc aaagaataca tttaacatta gaccaaccac
     5161 aatcgaattt ataacagttg gccataaaga agctataact aaagtacttt tattctgttt
     5221 acctaacttt ctagtaatat aaatcatact tgcacttata aatgtggcta atgttccaaa
     5281 aattatatca ggtacaccat atggtcctat tacatttgct aaaaaacaac ctaatgtaag
     5341 acctactata tatcctttat ctaaaaatgc caaaagcatc ataatctctg ctaccctaaa
     5401 ttgtattggt ccataactta taaatcccaa tgataatgtt aaaactgcat agattgctgt
     5461 aattgctgca gttagtgcta tattaatact attttttctc atatctgtct cctagtaaaa
     5521 gttttatttt taaaaaaatt aataacataa ctttatttta tacaaaatct ataaacttaa
     5581 acagtaattt tataaaaaca aattatttta gcgaactatt ttcccaattc attttatatt
     5641 atacaatata atacatacaa attcaatttt atatatatag aatatatgat attaaaatta
     5701 tatacaaact aaagataaat tttctattgt taattaaaaa cagcaaaaaa gagccttaaa
     5761 attaggctct aataatttat tttaaaatca gtgaactcta ctaccatctt ttaatttaga
     5821 taatatcatc caagtaccta tacaatcaat ttccagttgt ttctctattt catcatataa
     5881 catttcttga tatgatgtat ttaaaacaac attttcaacc aatttagaaa tttcctcttc
     5941 tgcaaaatca atttctattt gattttgttt ttctttaaaa aataccctta cttttctctg
     6001 acttattgaa cgaccctcaa agctgactaa acattctaaa atgttcttat ctcctctaaa
     6061 attatttact gctctcatat tatttagatt accagccaaa acatcatccc cttatttaat
     6121 tttgtatttt ataagtaaaa ttcataatat tataataact acttattaaa tatctttcaa
     6181 caggtatgac ataactggtt gtttaacatg taaaactagt ctaaattttc ataaataatt
     6241 atttattcat ttccataaaa actttttcag gtgtaatagg gagtgtattt attcttacac
     6301 caattccatt aaacacagct tcttgtattg ctggtaaagg tgtatttata acaacttctc
     6361 caacagattt agcaccaaat ggcccagttg gttcataagt ttcaacaaaa tctactttaa
     6421 catttccaat atcacatcta gctggaatct tgtattgcat aaatgtattt gtgtccatgc
     6481 ttcctttttc tgtgtatcta acttcttcaa ataatgacat tccaatccct tgaacaattc
     6541 caccttcaac ttgtatctta gctagatttt tatttataac cgttccacaa tctactacag
     6601 ctacataatt tactaaatca acttttccag tttctgtgtc aatttcagtt tctgcaaaac
     6661 ctgctataaa aggtggagga gatactgggc taccatgaga agcaagacct attaattgat
     6721 tagtatctgg accaattgta gaatcaactg ctatatcgaa taataaagtg ctaccttttt
     6781 tactagttaa ttttatacca tcaaattcta cttcatcctt ctcaacacct agtttagttg
     6841 ctccagcaga aattattttt tctcttaagt cttgagctgc cttaactact gccatacctg
     6901 ttacataagt agtacttgaa gcatatgaac ctgggtcata tggaactaag tcagtatcag
     6961 ctgatataac tgttatattt tcaatgcttg tatcaagaac ctcagcagcc atttgagcta
     7021 aaatcgtatc acttcctgta cccatatcag tagaacctat cataagagta taatctccac
     7081 agtcattcaa ttttatttca gctgaagact tatcaagacc ttgtatacca gaaccttgca
     7141 tagtaattgc catacccaca cttctaattt ttccattatc aagatgttta caaggatatt
     7201 tttcattcca tccaataagt tctttgcctt tatttataca ttttattaaa tcgacactat
     7261 ttaaagtttt accatatgca aatgtagttt caccttctgt taccacattt tttaacctta
     7321 aatctgttgg gtccattttt aatttattag caagcatatt tatagttgat tcaacagcaa
     7381 aacacccttg tgatgctcca taccctctaa gtgctcctgc tggcatctta ttagtatata
     7441 ccacatctgc aataaatctt gttgcttcaa ctttattata cattggtaaa gttttttctc
     7501 caaccaaacc aatagttgta gaagcatgct ctccatatgc tcctgtatca gaaagtgctt
     7561 ttatatctat tgcctttatt atgccatcat ttgtagcacc tagtctaact tttaatctca
     7621 ttgcatgtct acttgttgaa caattaaaag tttcttttct atcataaatt attttagctg
     7681 gtttccctgt ttttaaagta acaattgcag aaaaaatctc aacacatgca gtttgtttac
     7741 caccaaatcc gccaccaatt ctaggtttta taaccctaat tttgctagct ggtatttcta
     7801 gtgcacgaga taaatgtctt tttacatgaa atggtatttg agttgaactt actacaacca
     7861 atcttcccat atggtctaaa taattgtatg ccctatacgt ctccatcatt gcatgtgctt
     7921 gagcttgagt ataataagtt tcttcaatca ctacatcaca attacttaat actttttcta
     7981 catcaccttt tgtataatca tgatgggata ctatattttt ttctctttgc atacctatat
     8041 caaagttaca atgtctatct tcatcatgta ccatagtttt atttcctatt gcctcttcaa
     8101 aatccaaaac aggtgtaagt acttcatact ttactttgat aagattcatt gctttaattg
     8161 cagttttttc atctatagct gccactatag ctacttcgtc acctacatat cttacaacat
     8221 cttcaagaat taatctatca tatggagatg gctctggata tgtttgacca gcaagtgtaa
     8281 atcgagattt tggtacatct ttatatgtta aaacacattc aacaccatca accatttctg
     8341 cctttgatgt atctatatct tttatttttg cataagcgtg aggacttcta agtatcttta
     8401 ccaccaaagc atcttttgct gataaatcat ctgtatatac aggctttcct gttgtgatac
     8461 tcattccatc tattttcttg attccttttc caactatatt catgttctat tttacctcca
     8521 gataagtttt gatagctctt aactgtccca tataccctgt acatctacat agatttcctg
     8581 taagataatg ctttatttca tcatctgtag gattttcaag ctcatccttc attgcaagta
     8641 cagtaagtat aaagccagga gaacagaaac cacattgctc agctccttct tttaccaaaa
     8701 cttcactaaa ttctttaact tcattttcta aaccttcaat tgtagttatt tctttatcta
     8761 aagctctcaa tgtcagtgtt gcacaggata atgtaggttt cttgtcaatt aaaactgtac
     8821 ataaaccaca acagcctgtg tcacaacctc ttttcacact taaattacca acttttctta
     8881 aagtatcaac cagatattct tctggttcta tatcaacact ttttttcttc ccatttatat
     8941 taatctttac taacattaaa taacctccat tatagctctt tttaaaagta ctttactcat
     9001 agcttttcta tactccctag atgctctcat gttagaacca aaagttagtt cttctgatgc
     9061 tatttctact gctttatcta tattaatttc attgatttca ttgttagata gaaattcact
     9121 agcttgtttt gcaatcgtag ctttctgcgg tcttgctcct acacataact taaattgttc
     9181 catatgtttt gatacagata catttagaat tggataatca ctctttgcat ttctaagtga
     9241 tttataagaa gcattcttat ttgtcttctt tatgtatatc ttaataagta aatctttctc
     9301 ataatctcta tttagaaact cttcaagact aattctccca atattatata attctacttc
     9361 tgtatctaat gaaagtaatg ctactatcaa gtcagaaaaa ccatatttag aaaatactgt
     9421 tgcaccaact gttactacat ttctaaactg aactcctatt atatttttaa ctgaatcttc
     9481 tattattctt ccaaaattat tttttattat ggaacttgtt tctaatgttc taaaagtagt
     9541 catagaacca atctcaacgt aatcttcata ctcttttata taatctaaat ttaatttaga
     9601 taattctatt cctgttccta ttcttttttt ccccattctt aaaaaagcac ttccaccaat
     9661 tacttggtta gtttttcttt tatttaaaat tgagtacgct tcttctactg tatctggctg
     9721 tacaatatcc ataaccgtaa acataaattt cctcccttat ttgctattct tattttaaat
     9781 acaactaatt atatcatagc ttcaacaaat tttgataata aatatgtcta atatgtaaat
     9841 tctgtaaatt acttatacat aaaaaaatga ctatttcaat aatcatcatt agacaatatt
     9901 aaaatagcca ttaacaggta ctattttaaa gcaaaacttt aaaaagttga tactttttca
     9961 cttatattta tcacttcttc ttctaataat ccaagttttt tagctactaa ttttgtagta
    10021 cttccttgta ttactaatgt aattagtata gtcatgaata ctacagatga aatcacttcg
    10081 tatccaggaa ctttcattgc tgaaataata ccacaaagtg ctgctggtat tacgcctgtt
    10141 tcccttaccc acatcataaa taatatttca cttttactcc attttgcttc cctgtctaca
    10201 agtgtacaaa ctaaaacgca aagtggtctt gctataaaca ttaatactaa tactgtaatt
    10261 acagatggca taaaatattt acttaactga gccaaattaa cttggctacc caatattata
    10321 aatattgcca tacgacaaat agtacctaaa gtttcagcaa cataaaaatc tgcatcataa
    10381 gatttttgac ttaaccaaat tttaaagttt ttcttgttac cagttattat acctacaata
    10441 aagcaagaca tatatccact tccacctaat tttgtagata attcatatgc aactacaact
    10501 gaaataacag atattattgg tgcaaaatct ttaaatattc cataaggttt atcattaact
    10561 aatttcaaaa gcagtattcc tgtaattaaa ccaactaaaa ctccgacaat aaccattgtc
    10621 cccagttcat aaatattttc acctaatgaa aatttatttg acaaaattac agccaacact
    10681 gctgatgtta gtatagctcc tgttgcatca ttaaaagctg attcacttat tacagtttgt
    10741 tttaccctat cctttatctt tacctgatta aatataggta caagagtggc tgggtctgtt
    10801 gatgctatta tagttcctgc tagtaaagca gtcattgcac ttatcccaaa agtaaatcct
    10861 attacttgtt gcattataaa agcagatatc acaactccta aagtagctaa taagaataca
    10921 gatatcttca catttctcaa tacttttaaa cttatttctt ttccacctaa atataaaata
    10981 aatgcagaac caaatgtaag tattagttga ttttctattt gaaatccacg aatatctata
    11041 aattttaaaa atgatggtcc tattaaaata cctacaagta aatataacac tacatctgga
    11101 acctttatta tttcactaag cttactacaa attattccag ttatacttac aatagcaaaa
    11161 attatcaata aattattgct ggcaattgtg tgtatagatg cttccatgtc cgtctctcct
    11221 cccgatttgc atacattatg caatatactt attgttttac tatataatta tagcacacaa
    11281 ataaatgtta tcaatcattt tttttaggac atgcaattta gctttcattt ttgacaatta
    11341 aataacgctt atataatttt gctatttttt gctagttatt aaaaggttga ttttgtcaag
    11401 tttatagtat atatatatta atatttttta tatccatatc tttttagata tttttcgact
    11461 ttttcctcca ttaaaataag tttaaattta acaataaaac atttcattat atatattttt
    11521 taaaatgtac cattttcaac attttcatta acttggtcta ttcatttttt tcttatctat
    11581 tctatatcca agcatattcc ctatattttt acttacatgt aattcttgag ctatttcaag
    11641 tttattatca ttgctttgtt ttatcttaga aatctcactt tgtttttcat tttgtttatc
    11701 ttgtttcata gtttctcctt tcaaaacaat atcacttttt ctgtttatta cttattattt
    11761 caaatttcta taattttaat caaaaaaggg aaatatctca atataatata gcttattcaa
    11821 caccatattt atatatagaa tttccctaat tattttatta atttaatttt tcaataacct
    11881 tatctaaatt agaatttact ttatcttcct ttttccaaga atttaatgta taatgcgttc
    11941 caaatgtaaa taaacctgaa actattaata taaaatagta tacaaaccca ctatataaga
    12001 gtacagagta ccccaataat tcttttggaa ttatattgga gaacatagta aaaaatgtaa
    12061 cctcattagc tccaacattt cctggtgttg gaattggtga tatagccata tataaaaaga
    12121 cctgtaatgt cattatatgt acatatgaaa ctcctcttaa atttgaggct ttatacacac
    12181 aataaactat actgaaatat gcgattaatt gtaacacagt aagtaatata cttaaaacta
    12241 agattcttac atttttaata aatattttta tagaataatt ataatcatca atataatgat
    12301 ttattctatc acgttttgaa tctaaaaatt taaatgtttt aaatttagat aaaaaattaa
    12361 tcaaaacttc tgctatcatt tttacttgtt ttggactaaa tactattagt agtccaccta
    12421 acaacatact tacattcata atcattccaa aagttatcaa gactttcaca gaatgtactt
    12481 gctccatcag taatgactta tttagcaaaa ttaaaattcc acaaaataca gtaactgtac
    12541 tttgaaatac tacagtttta ttagtaacta tagccactga tttactaagg cttacatcat
    12601 attttgtaag tgcatatatt tgcattggtt gactcccaga tgcaaatgga gtaactaagt
    12661 tatagtaaaa tcccattgta gccattttaa taccaataaa ttttactttt gttttttgaa
    12721 ctgcatttat tatcaaatga gttacaatag attcaattat catatatact ataattgtca
    12781 atatgccaag aaatatataa gtcttattta ctagccttat aattttaggt attagtttta
    12841 tatctaaagt agttaatact aaataagtag taatacatat caaaaataat aaaaatccat
    12901 attgaataaa atctttttct cttttggata attttctcat ttattttctc ctaaattttt
    12961 tcatatcact atacatagta tactacttaa cctattattt gcaagactaa aaaagataag
    13021 tctttatttg acataaatac acttataaat ttttaaatat ttttactcct ttagtagaaa
    13081 taattctcca tatcataaaa tctaatatca aagtaagtat acttgccaaa ataatatata
    13141 tatttaaaaa cgaaattcca agtaatacat atatacctcc aagtataatt acataagcta
    13201 atgatactaa cattgtaact atcatacttg cacttctttt tactacagcc acctcatttt
    13261 tccaatcaag gtttgggtat aataaatttg ataataatcc catcaatgct acaaacattg
    13321 aaaaacttcc aatcaaacag attgatacaa taataaactg aatttcaaag tctaatctta
    13381 tagatactaa tattagacat aaaatagata gtggtgcatt caataaaaaa ttcatcaata
    13441 tttttgacca gaatatttct ctttcatcta ttggagaaga tttcagtatc cataagtttt
    13501 ttccttcaag agaaattgaa cagtatgttg tacaattcat tactattata aagaagaata
    13561 ctcccaataa ttgtattttt ataagattaa aatctatatt caatttcagt aactcaccca
    13621 ctttatctgc tccaaataat aatattaaaa ttgtacctac tattagaaat aacaaacctg
    13681 cagatgaatt taaaaagtat ataaacgaag aagtatatct cttaaattct ttttttaata
    13741 aagcttttga aggtcttgaa gttttttgac ccttaaattc ataatttttt gacttatatc
    13801 cttcactcat cttagcattt atatctttaa atttttttgc aaacagagtt acaaacataa
    13861 aaaatggtat tattgagatg gctataaatg ctaaaaatga aactatactt cctgttttaa
    13921 gagcatcaac aaaataatat ataggaggat atacttttct aatcgtctct gaaatagaca
    13981 cactattctt tagcatttca actgacatag aattaagtct tgacataagt agggtataaa
    14041 gcaacatcaa tataatgcta cctatgatta atactaaatt tttgtatttt attcttgatg
    14101 atatctgccc tataaataga aaaattattg atgaagcaac tatcggtaat aatggtaaag
    14161 ctaaaaatag caatatcaaa taagggaaat aagttatact tacatcagaa tttaaaaagt
    14221 aaaccactgc aggtataatc atacatattg aagaaaataa atagtttgct ccaaccaaca
    14281 ttaatatctt acttgctagt acagtagatt cttttatagg taaactagtc aaaaggtcta
    14341 aatcttttgc ttgaaataga tatgatgacg ttttatataa tgatgtaaca atagttgtta
    14401 atgttgataa tccaaaacca aatatcagta gcatttccag ttgatttatt tgctttaaga
    14461 tatcaactaa agagagactt aagctcgtta cataaaaaat taatagaccc gctattataa
    14521 caactgaaag catcattccc attatttttt gtttttctct accatcagct ttttttaacg
    14581 catttaattt aaattcattt attatattat tttttattaa tatacttaga ttgctcatat
    14641 tttatcattc ctcactttag acactatatt gtataaaaaa cattttattt ctctattaat
    14701 tccatgaaaa tactttcaag tgaattactt cccttaactt cttctgtagt tccataagca
    14761 attatatttc catcttttat tatggcaatc ttatcacaaa ttttttcagc aacttctaaa
    14821 acgtgtgttg agaaaaatat acaaccacct ttgtcacaaa actccctcat aatttccttc
    14881 aatataaagg aagcttttgg gtcaagacct acaaaaggtt catcaagaat taagattttt
    14941 gggctgtgta tcaaagccga aattatagct aatttttgtt tcataccatg tgaatatgaa
    15001 gatattaaat ctcctaatgc tttattgagt tcaaacttat ttgaataata ttttattaac
    15061 tcttctcttt tatctttggc aacttcaaat atgtcagcta taaaattaag gtattgtata
    15121 ccagttaatg actcgtataa atctggatta tcaggtatat atgccatttc ctttttacat
    15181 tcaacaggct gtttttttat agatttagaa tttattagta cctctccctc ttcaaaatcg
    15241 tgtattccaa caattgcttt aatagtagta gttttacctg ctccattatg tcctataaac
    15301 ccaaaaagct ctccatcatt tacatcaaat gagacactac ttactacttt tttattttta
    15361 tatgatttag atacattgat tacttttaac ataatttccc tccatattat agttttgata
    15421 tttgttatat ataatatata acaaatatca aacaattaca acttttattt gtttatttta
    15481 gaaatctata aaatgcaaag gtatcagaaa tataaaggta taaatataat tgatatttac
    15541 tttcaaatta cacataatta taaaagaata tatagttcga tttgaataaa caatgtataa
    15601 taaaaaatag ttgactataa ttattaaaat ataaggagta aaatatgaat acatttgaac
    15661 aattaaaaat aagttccact ctaatagatg gactcaaaaa acaagacata acttctccaa
    15721 cagaagttca gtcacttgtt atagggaata taattcaaaa taaggattta ttgattaatt
    15781 cacagactgg aacaggaaaa acactagcat accttttacc tatatttgaa aaaattgata
    15841 catcaaaaag agaaacacaa gctcttatac ttgcacctac gcatgaatta gtaatgcaga
    15901 ttacaaacca ggttgaatta ttggctaaaa atgcagaact ctccgttact tctttagctt
    15961 taattgggga ggtcaatata caaaaacaaa taaaaaatat aaaagcagta aaaccacaca
    16021 tagtaattgg ctcttgtgga agagttttag atttgataaa acaaaagaag ctaaaatcac
    16081 ataatataaa aactattgtc ttagatgaag tggacaatct attgaatgga aaaaatataa
    16141 cttgtataga agacataata agaacaacgt taagagatag acaaattata ggatgctctg
    16201 caagtcttac tgatagcact ataaaaattt gtgataaact tatgaaggag tttgaaataa
    16261 taaaaacaaa ggaaaaatca caaataaatc ctaacatcaa tcactcatat ttattaggtg
    16321 agataaggga taaatttact tttcttagaa aggcattagc ggctacaaat ccaaaaaaag
    16381 ctattgtatt tgtaaataat gaaaaaaata tagaagtcat agtatcaaaa ctaaattatc
    16441 ataattacaa agcaatagga atttttggaa atatggaaaa agaagataga aagaatgcaa
    16501 taaataaatt taaacttggt aaagcaaaga ttttaattac aactgattta tctgctcgtg
    16561 gactagatat tgtggatgta agtcatgttt ttaacttgga ttttccaaaa agtaaaaatg
    16621 aatacctgca tagatgtggt cgaactgcta gaggaaatcg aagtggtaac acaatctcaa
    16681 taataacaaa aaaagaatta gatattataa aagatttgca aaaagagttc aatatagtaa
    16741 ttacacctaa aactttacaa aatggagaac taatagacat tattaaataa tacaataaat
    16801 acaaaaatac aacaaataca aaagagctgt agtttatcat cacaattgat aataaattac
    16861 agccctttat tttatattaa attaaaattt taaataatac ctattatagt agccaaagtt
    16921 ttattataaa taatattgcc agaacaatca ttactacaga aacatgtttt ttgtcttctg
    16981 cctttttagc tccaaatata ttataaaata tatttacgaa aacataagtt aatataccta
    17041 aagttaaacc atcacctata ctatatgtta atgccataca agcaatagta acaaaagctg
    17101 gaacaccttc agttatatta tcaaactcta tatccttaac tgtaccaagc attaaatatc
    17161 caacatatat taaagctggt gctgtagcac atgatggaat tgctataaat acaggagaga
    17221 aaaacattgc agctaagaat aaaattccaa ctgttattgc tgtccatcca gttcttccac
    17281 ctgcgataac tcctgttgaa ctctcaacat aagttgtaac tgtagatact ccaagtcctg
    17341 caccaactgt agttgcaacc gcatctgtaa gtaaggctct acctacatta ggaacattcc
    17401 ctttttcatc taacatgttt gctttagaac aaacaccaac taatgtacct actgtatcaa
    17461 aaaaatcaac aaataaaaat gtacaaacta ctactaaaaa accacctata tttgttggat
    17521 gtagtacata tcctaaatct attttacctg ctattggtgc taaactttcg aatttaaata
    17581 atccaccagg taaatatata cctaattttt gtgcatactc tggatttata aaagcaaatg
    17641 cccaagcaag taatgaactc actactattc caaaaagtat agaaccttta actctttttt
    17701 tatctaatac agcaataatt attaatccta cacaagttat tattactgct ggtgtaaatc
    17761 tacccatttt gataagagtg gcttggtctc caataacaat tccactgtta actagaccta
    17821 taagtgcaat aaatattcct ataccacctg taacagctaa tttcatattt tttggtatcg
    17881 catttacaac agcctcacga actccactta ctgataatac tataaaaata ataccttcta
    17941 caaatactgc tgtaagagct acttcccaag gaacacccat ttgtaaaact actgtatatg
    18001 caaaaaatgc attaagaccc atacctgatg ctaaagcaaa aggaaggtta gcaactacac
    18061 ccattaaaat acatccaaat gctgctgcta aacaagtacc tgtaacaagt gcacctgcag
    18121 gcatgcctgt ctcagataaa atatttggat ttacagctat tatataagcc atagttaaaa
    18181 aagtagttac tcctgcaatt atttccttct tcatgtcgac atttttatta gtcaaaattg
    18241 gaaaaagttt ctgcatagta ctactgtttg ttgtttgcat aacaacacct cctattaaat
    18301 tttacaaaaa aacgacacag tagttgataa gctgagccgt atccttcata attcagttaa
    18361 ttaaatattt aattaactaa ataatagtat acatagtcag aatatttacg gtattccggt
    18421 agaaacttat gacccatatt gtcaaaatta tatgttatac agtacaaaac atgaattttt
    18481 ctttacgaat attattttaa tttatataat taattttgtc aatatatacg tatatattgt
    18541 attgattttg tattaatatt cgattatatt aaatattgat ttattaaatt caaattataa
    18601 ttatattctt tacattttaa aaaaatatat gatattttga tacaatttat ttatagtttg
    18661 gatataaagt ttatgttaag attatactat aataaattaa taattttttt atttggagga
    18721 ataatgtgaa agatttaact acaggtcatg agggaaagtc catattcttt tttgccatgc
    18781 ctatgcttat tggtagttta tttcaacaac tatacaatac agctgacagt ataatagttg
    18841 gtagatttat tggaaaagaa gcaatggcgg cagtctctgg agctaaccct ataatgtttt
    18901 tattggtggc agcgcttatg ggtgttagcc ttggattttc tattttagtg tcacaatttt
    18961 atggctcagg agatttaaaa aaggtaaaag ctactattga tactacatat atacttttat
    19021 ttattggttc tatattaata agtattcttg gaatagtatt tggtggccca atgcttaagc
    19081 ttatgaatac accagaatcc gtttttgctc aatcaaaatt gtatcttact ataatattta
    19141 gtggaatatt attttctgct ggatataatt cagtaagtgc aatacttaga ggacttggag
    19201 attcagtaac tccactttat tttctgataa tagccacaat tctaaatata gttttagact
    19261 taacttttat tgtagtgcta agaatgggtg ttgagggcgt tgcacttgcc actataatgg
    19321 ctcaggcagt atcatttata ataagtataa tttatttaaa taaaaaacat gaagtgctta
    19381 aatttaaaat caagggaatt gtatatgata acaaaatatt taaagatgga cttagattag
    19441 gacttccaag tggagttcaa caaatgttgt tttcaattgg aaatatggct cttcaatttt
    19501 tagttaatag ttatggtaca tctgctatgg cagcttttgg tgctggtctt aggatagaaa
    19561 attttataag cttacctatt atgaatcttg gttctgctgt ttctactttt gttgctcaaa
    19621 acataggtgc tggagaaaat gaaagagtta aaaaaggcat tcgagaatct ataaaaatga
    19681 ccttagtttt agcagttaca gttattgctt taattttgct atttagggaa aatctaattg
    19741 ctctattcaa tactgataaa gatgtcatta aaattggctc ttcttactta tttataatag
    19801 gaccattctt cttatttatt ggaacttctt ttgtactttc aagtgcaatg aaaggtgctg
    19861 gtgattccat gtttgcactt ataagctcaa tagtatcttt atggcttgga agacttccag
    19921 cttcttatat gctttctaaa ttttttggaa cagacggaat ttggatgggt attccttttg
    19981 gttggacttt aggtcttatt gttacagtta tctactataa gaaaggacat tggaaaacta
    20041 aagctattgt aaatcataga atcaatgaat aatcttttta taaaatgtat tcacattcat
    20101 tgtattcacc tccattatga tataataaat tatggaggtg aatataaaaa tgggtattat
    20161 tcttaagcca aaacaatttt atatgactgt tatagctacc ataattctct acttctctct
    20221 taattacagt ttcaacataa aattttctat atgcttatct tttttaacta tcttgatatg
    20281 ggctgtagac tcagttgaaa aaacttttgt tgcattgttt tttgtaattc tagcgtttat
    20341 atttaacatt gcaccaataa aggttatttt acagttttta tttacagaaa atttttacat
    20401 aataattctt gcatacataa ttactaatgc agttacaaaa acaggtgtcg caaaaattat
    20461 ttctgagaag ttaattttaa atactgtaaa tacccctaaa aaaatgattc ttttatcgta
    20521 tattttaggt atacttttaa tattttttat cccacaacca tttccaaggg ttattcttgt
    20581 atctgctttt tacaaggagt ttttaaaaga acaacagata actgaagatt caaaatctat
    20641 acttttattt agtatattta cagcatctac ctttacatca atgttttttg taaatggaga
    20701 cactcttcta aattatgttg tactagaact tggaaattgt aatataaatt ggggtcaatg
    20761 ggctttttat atgtctgttc caactataat tacttgtttt ataacttatt ttttatttat
    20821 ctttgtcttt aaaaaagaat tgcattcaat aaaatttatt tctaatgaaa atcttgaggg
    20881 taataaactt catttttcat attctaattt aaaaaaagaa tttaatttgc taaacaaaga
    20941 gcaaaaacac gtatttttat gcctaggaat aatgtttttt atgtttttaa ctcagttcat
    21001 acataacata aacacattaa ttataatgtc aatttgtgta cttcttttat tactaagaaa
    21061 aatagttgga tttagtactt taaaagaaat aaattggaag gtccttattt tttttatagc
    21121 agcattttca attggaggag tgttaaagta ctctggagtt gtagatataa tgggaaatta
    21181 tttgataaag tttataccaa actcttcaga aattatttca atattgtttt tgataactct
    21241 cacaataatc ttgaatatat gtcttggaag tgctgtcact acatcatctg tagtaatacc
    21301 gttacttgga agtttacata tactaaagga aaatagtgtt actttatgtc tatttgtcta
    21361 cattatagta agcatacagt acatattacc atttcatcat gctacaataa tggttggtca
    21421 tggtgaaaat ctgtataata gcaaggttat tttcaaatac ggtttaactt tgattccttt
    21481 aacctacttt ataataatat gtataacatt cccttggtgg aaatttatag gactagaaat
    21541 ctaaaaaaga tgaaaatatg aattaactta agataataac gaaattatta aaaagaaaat
    21601 tcatattttc atctttttat ataagttctt gtgaaattgg acaaaactac tcttttacca
    21661 taatactaaa tattatttgt tttacttcct tttccaaaag tattctccca atcctctata
    21721 aacttatcta cactccaatc agttaatgga tgattcatca tagatttaca aatatcatat
    21781 ggtactgtaa cactatgcac cccatgttgc attaattcta taacttgttg tgcattttta
    21841 aaactggctg caagtacttt tgtatccatt ttataagtat ctattatttt tataagttct
    21901 gaaaccatag ctactccatc accagatata ttatcaagcc tatttacata aggtgcaata
    21961 taatttgctc cagcctttgc agctaaaaaa ccttgatgag cagtgaatat tgcagtagca
    22021 gttattttta taccttttct gtgaaggtct tttatagctc ttaaaccatc ttgtgttaca
    22081 ggtattttta catatatatt ttttctcaaa ctacttatat ataatgcttc ttctaatatt
    22141 tcttcatact ttgtacttaa cacttgagca tgtataggca tatcctcacc tataatctca
    22201 ccaatttcat ttataagttg cttaaaattc tttttttctt ttgaaacaat acttggattt
    22261 gtagttacac catctattgg taaacaagta cataactcct taatctcctc cacattacct
    22321 gtatctaaga ttagttgcat taaaatatcc ccctttaatc tttctttatt cttattatat
    22381 attgatttgg tattattttc aacattttgc ttattgtttt ttatttttta ttattgtttt
    22441 acttttcctt cttagtttta taattttttt atttactaaa ttctaaatat atagttagaa
    22501 aaaacatact ttttatatta aattaatttt gtatttcatg ttaaaatagt tgatatattg
    22561 tattttatct tataatattt actataatac tatattgcga aaagaggtag aaaatgtttg
    22621 cagaagaaag aatccaagct atattaaata tcctaaaaaa agaaggtaga gttactgtca
    22681 aagagctcag ttctaaattt aatgttacag aagattgtat aagaaaagat ttaaaaaata
    22741 tagaaaagat ttcttcaata agaagaattt atggaggagc tgtactagct agagaaacac
    22801 tagagaatca ggatacaaaa gacagaaaag aaattaatat tccaacaaag aaaataatag
    22861 cagaaaaagc atttaattta attgaagata gagaaactat atttttagat atctctacaa
    22921 ttaacatctt gcttgcaaag ttgttagctg aaagtaataa aaaagtaaca cttgttacaa
    22981 atatgctgga tatactaaat gtagttactt caaaaccaaa taatttaaat ataatttcca
    23041 ctggaggttt attaaatctc agtttagacg gttttgtcgg tactccaact atagagttta
    23101 tatcgaaata taagtttgat aagactttta tgggaagttg tggagtagat gtattcaact
    23161 cttcacttac aacttttgaa attgaagatg gtcttacgaa gaaggctata ataaattcaa
    23221 gtaaaaaagt atttatagtt atggaagata aaaagtttaa atttgatgga aatttcaagt
    23281 ttgctcattt agaagatatt agttctataa ttacagaaaa aacgcctact cctgatatag
    23341 tagatatttt atcagaattt aatgtaaatg ttttataagt ttaattatat gttttatagg
    23401 atttcttata aatataaatt tttatttgat aaatattctt aaaaacatat ttctataata
    23461 tttattttat ccttagtatc tattttttaa aatctagttc tataacatct actttatcct
    23521 tatgtctatt tataaaacta atttgaaata gactttctaa atctaataca gttattttta
    23581 gaaagtctat ttccttaaat aaactattta atattactgg ctacttttta tatgaataca
    23641 ataatttgtt attcataaat aaaagcttat ttcatttcat tcttcatttg cttctctaat
    23701 tctttagaaa atttcttttg ttcatatctt tccatcatct catctttttt catttctaag
    23761 tttaccatag caccttgtgc atcatctttc aaatcttcag ctgtattttt cataacataa
    23821 gctgtctttt taacaccttc ttttaaatct tctttcatat ttttcatatc tctttttaat
    23881 ctatccatca aaactacctc ctctgtaaat ataatacttc ctatatttat ttttcccaaa
    23941 gtacatatat ttatttgtaa tatcaattat aatttttaag tcttaaatat agtttaaact
    24001 atctaaatct atacatttca ataaattaaa tattttttat ttcaaaataa aaataacact
    24061 aagcatagat tatatgctcg gtgttatttt ttaaattcat agtaacttaa ttgttgggtt
    24121 actataatga tgacttatat ggaggatgta aggaaatctc atcattatag ttggtgtatt
    24181 ttatggtttt aagcttattt atatttatat aatacagttt cattatgaat tttttgtgat
    24241 tttaaaatga actattattg aaagttatat attctttata ataagtaatt aatttttaaa
    24301 ttctactgtg aatactacag agttttcttt gttttttatg ctataatcaa acccatgact
    24361 tttaaaaatt tggctgacta tataaagtcc aagtccactt cctccagttt ttctcgaacg
    24421 agatttttct attctataaa atggattaaa tatttcttct aaataacgtt tctcgatagt
    24481 tacaccagta ttttcaattt ctaaaaccac tctttgatta gaagtctttt tacttattcg
    24541 tttattttta tcatagagtc taattataag ctctgattct tcaggagaat attttatggc
    24601 attatttatt atattattga ttgccttagt tattctctct tggtctgctt taatttccaa
    24661 attttcttct atttttaaaa tagttttcat atgtttttct tctattaaaa atacttgtct
    24721 ctttacaagt ctatttaata attcacttat atttattgat accaatttca aatctttttc
    24781 aagtatttct gattttgaaa cctctatcat ttcatttact aaatctttta attcttgtgt
    24841 acactcatac gattttttca gataagtatc cctatcctta tacttaccta cactataaat
    24901 cataccttca atttgaccac ttattatggt tattggagtt tttagttcat gtgatattgt
    24961 agcaacaaaa tccttccttc tatattcctg ttctctctca ctctctatta tgtttataag
    25021 aggctttgtt attacaattg aatatatata tgctccaata atcgctatca atattgctat
    25081 tgatatgatg tatggcatta gttttcttat aacttcgttt gcttcgtcaa ttggttgtaa
    25141 tggcataacg agttctaaag tatatggacc atcttttgca tctttagtat atataggtat
    25201 agaagttcta tactcatcct caagactatt aatcatgtac ttactatatc ttaaaataac
    25261 tacttcattc ttaccatata caattttacc ttggttatct tttaataaaa tagccaaatt
    25321 ttggtcttta gccatataat aaagtctttc ttctaaagta tatgtatcga aatgaattga
    25381 actatctact aaagatttca aactttcttg aagatactca attttatact catgataata
    25441 tgatggcaat aaaaaatata aaattagata tattattaaa gctaatgcta ttaataatga
    25501 tgtcgttatt gaaaataact tatactttat acttaacttt tcccacttat caaatatcct
    25561 tctcaagtgt atatcctatt ccttttacag ttttaatata tggtaatgat attttttttc
    25621 ttatattttt tatatgtgca tcaacaatcc tagtatctcc ataatagtca taaccccata
    25681 tactatccaa aagaccttcc ctagttataa cttgtggata cttttctatc aaagctttta
    25741 atatattaaa ctcttttagt gtaagttcta taggttctcc atctatctct gcaatatatg
    25801 tgtttaaatc taattttaat ttttcaaaaa ctataaattt gtcatttata gtcttgttac
    25861 ttcgccttaa aattgcttct actcttttta taagaagatt aaatgaaaat ggttttgtta
    25921 tataatcatc acattctaag tcaaaccctt taagttggtc tccttcatca tttaaagcag
    25981 ttaaaaatat aattggaacg cttgatgact ttcttatcat tttacaaact ccataaccat
    26041 ctaagtttgg catcattata tctaatatta ctaaatcata acttccttgc ttaaactttt
    26101 gtataccttc caacccatca tttgctgtat caacttgata accttctgca cttaaaaatt
    26161 ctgatattaa ctcttgtata tttgaatcat cttcaattac aagtattgac gaattcattc
    26221 tatcaatcct ttctatttta tttaaaattt cgtatattac ttatatttta tcttattgtt
    26281 gtgaatttta catgaaaaaa gagctatctt aatttgtaaa ttaatccttt taatttaaag
    26341 atagctcttt tggatacatt ttatttaatt tattaatcta atctctctta tatgccttga
    26401 agtttttaag tctaagtgca tttgatacga ctgaaactga acttaagctc attgctgctg
    26461 ctgcaatcat tgggtttaat aaaggtcctc caaatacata taatattcct gctgctacag
    26521 gtataccaat tgtattatat ccaaatgccc aaaataggtt ttgttttata ttttttatag
    26581 tttcatgact aagtttaatt gctgttggaa catcaattaa atcactcttc ataagtacta
    26641 tatccgcaga ttcaatggct acatccgttc cacttcctat tgctatccct atatctgctt
    26701 ttgcaagagc tggggcatca tttattccat cccctaccat tgcaacaaac tttccttgat
    26761 tttgtagttt ttcaacttct tttgacttat cttctggtaa aacctctgcc aaaaccatat
    26821 ctataccgac ttgatttgct atagcatttg cagttttcgc attatctcca gttaccattg
    26881 caacttttat tcccatatca tgaagtattt ctattgcttt tttactactt tctttgacta
    26941 catctgcaac tgctattata cctgataaat ttccatctac agctatatac ataggtgttt
    27001 taccttggct tgccaatata tttgattttt cttctaaatc cccaagcttt atattattgt
    27061 cattcataag ctttctattt ccaagtaata tactttcatc attaatagta acttgtatac
    27121 cagcacctgg tatggcttta aaattatcaa ctttttcaaa ttttatattc ttctcttctc
    27181 catacttaac tattgcttct ccaagaggat gttctgaacc tttttctgca cttgaagcaa
    27241 tcttgataag atattcttct tttacattat tatttaatac tatatctgtt acttttggct
    27301 ttccttctgt tatagtacct gttttatcaa atatcactgt atttacttta tgtgcagatt
    27361 ctaatgcctc tccacctttt atcaagattc cattttctgc gccctttcca gtcccaacca
    27421 ttatagcagt tggtgttgct aatcctaatg cacaaggaca agcaattaca agtactgata
    27481 taaatatagt aagtacaaat actatatctt ttcctcctat taaaaaccac aataatgatg
    27541 caactacagc tattgcaatt actattggta caaaatatcc agatacagta tcggcaagtt
    27601 tagcaatagg tgcttttgta ccttgtgcat cttcaactaa ctttattatt tgggcaagag
    27661 cagtatctcc accaattttt tcagccttaa acttaataac accattttta ttaatactag
    27721 ctcctgtcac cttacttcca acattctttt ctactggtat actttcacct gtaagcattg
    27781 attcatcaac tgatgtatat ccttctatta caactccatc cacaggtatt ttagttcctg
    27841 gttttactaa tagtatatct cctatctcta cttcttctat aggagtttca acttctttac
    27901 catcaactaa cactattgca gttttaggtt gtagccccat aagcttttta attgcttctg
    27961 atgtttttcc ttttgatttt gattctaaat atttaccaag taagataagt gctattatta
    28021 ttcctgcact ttcataatac aactgatgat ggtgcatacc ttgaatttgt ccattggcta
    28081 tttgtagtgt cgtatataga ctatataaaa atgcggctaa tgttcctatt gcaactaaag
    28141 aatccatatt agggcttaaa gaaaaaagtg atttaaaccc atttatataa aatttataac
    28201 cagctatcat tactggtatt actaaaatta actgaattaa tgcataatta aaagtatttg
    28261 tcataggatt tataatttct ggcaaaggcc atggccctat aggctttatt atcataggtc
    28321 ccattgctat ataaaacaga ggtactgcaa atactattgc aactataaat ttaacaaata
    28381 aagacttcat ttctctttct tttctcaatt tatcttcatc cacatcaacc ttatttttta
    28441 cctcttctat tggtttatat ccagcttttt caatagctgc ttttatttga gataatttta
    28501 cttttgatgg gtcatagtct atattagctt tatctgttgc aatattcaca ctaatacttt
    28561 ctactccatc caattttttt accactctct ctacagcttt tgcacaagct gcacatgtca
    28621 ttccatcaat tttcatatca atttttttat tactttcttc ctttataatt ccatatcctg
    28681 ctttttctac aacctgcttt atatcatcaa aattaacctt agaattatca tattctattt
    28741 taagtttttc agtagctata tttacacttt ggtcatatac tccatccatc ttcttagtta
    28801 ctctctctac tgcctttgca caagctgcac atgtcatacc tgtaatttta taactttcta
    28861 ccactttatt tgaactcata ataaaatctt cctttctttc aatatatttt cagctaattt
    28921 gtaacgtttt attttgatat gtaatattga taaattactt atttagaaat ctatattttt
    28981 attatacccc ctataggtat attaaatcaa tattttttta ataaataaat gtattagtta
    29041 tatttatttg tatttaatag aaaagtatac tcataattaa atgtatatat aaaaatagag
    29101 catctaaatt gtttaatgct tatacaattt agatgctcta tttattatat tttatttaaa
    29161 atttattctt tacatgcttc aaaaaactct gcttctgttt cctttatttc aagctcattg
    29221 tctattattc caacagcttc ttttttaaat gctctacact gacctataca accagtcttt
    29281 acattttctt ctccaaccaa agtttttagc ttatttacat ccacatttga acagtttgga
    29341 catactctta tcatatttaa gttcctccta attaatgtct aattaatact tttataccca
    29401 aatataaact ttataaaagt ttttttaata taaattatta ccatatatac catttatatc
    29461 ctattgcgag tattacatat taattttata tattattaat actacatgta cggtggtatc
    29521 tgttgttttc tcactatttc caattcctta atttctaaag acttaatcac atttacttta
    29581 tagttttctt tagactttat atacaaaaca tcttctatct ttttaccttc aataaattta
    29641 tgagaccact taagaagttc ttcaaaatta caaacttctt cttttacaaa agtatcactt
    29701 tcacttgcaa aatatttaat tattattttg gttacttcca acatatatca tcctttactc
    29761 ttttattaat ctttttatct attaaggtta ttatttgtct aaaaaatttt tttaaacaaa
    29821 ataattttca gatgcaaaac taacagtttt attcaattta aactatatta atacaattta
    29881 atatattcct ccttgtacct aataatatat tgtgctataa ttaataagtt attttaatcg
    29941 aagggagcaa caaaaatgtc acaaaaacat aaaattataa atatcgcagt tatagcccac
    30001 gttgacgctg gaaaatcaac attggttgat gctttccttt ctcaaagcgg tgtttttaga
    30061 aagaacgaag tagttaaaga ctgcgttatg gacagtaacg accttgaaaa agaaagaggc
    30121 ataactatat attcaaaaaa ctgtgcaata aactatgaag attacaaaat aaacatagtt
    30181 gatactccag gacacagtga cttttcttct gaagttgaac gtgttatgaa aactgttgac
    30241 acagttattc tattagttga tgctagtgaa ggcccaatgc ctcaaactag attcgtttta
    30301 caaaaatctt tagagttcgg tttaaaacca atattattta taaacaagat tgataaaaaa
    30361 gaccagagag cggaagaagt agttaatgaa gttttcgatt tatttgtaga cttaaatgca
    30421 acagatgagc aatgcgaatt tcctataata tatggtattg ctaaacaagg tattgctaaa
    30481 cttgaaatgg atgatgatag tgaagacctt tctcctctat ttaaaactat tgtaaatcac
    30541 gttgaagctt atcctaatta cgataatgaa cctctacagt tccaaatatc agctcttgca
    30601 tatgatgatt atgtaggtag acttggtata ggtagaattt acaaaggtac tcttaaaaac
    30661 aatacacaag ttgctatatg tagagaagat tctgttgtat ctaaaggaaa agtatcaaaa
    30721 ctttctgtgt atgaaggttt aaaacaagtt gaagttgatg aagctactag tggagaaata
    30781 gttgttatag ctggtattcc tgatatatct ataggtgaaa ctatatgcga tttagatagt
    30841 ccactaccta tggaaatgat aaaaatagaa gagcctactc tttctatgaa cttcttagta
    30901 aacgactctc cattcgttgg aaaaagtgga aaattcgtta caactagaca tttgaaagat
    30961 agacttgaaa aggaacttga agtaaatgtt ggtcttaaag ttgaacctct tgatactact
    31021 gatggataca aagtttctgg acgtggagag cttcacttat ctatactact tgaaaatatg
    31081 agacgtgaag gttatgaagt tggtgtttct aaacctgaag ttttaatgca taaagaagat
    31141 ggaaaactaa tggaaccaat agaaagagtt gttgtaaact gtcctgaagt ttactctggt
    31201 actattataa atgaattaaa catgagaaaa ggtatgatgg agtctatgtc aatagaagga
    31261 gactatgtaa aaatagagtt cttagcacct actcgtggtc ttttaggata tcgaagtgaa
    31321 tttataaacg ctactcgtgg agaaggtact ttagttcgtt catttgaaaa atttgaagaa
    31381 tttaaaggag aaataccttc aagaggaaat ggtgttttaa tagcacaagg acctggtgtt
    31441 actatggggt attctcttaa tgccttaagt gatagagctg taatgtttgt agaccctggt
    31501 gtagaagttt acgaaggtat gataattggt atgaattcca gaaaagatga tatggtagtc
    31561 aatccttgta aaaacaagaa aatgagtaac gtacgtgctt ctggttcaga tgatgctata
    31621 aaattatctc ctcctagaat atttactctt gaagaagcac tagagtttat agaagatgat
    31681 gaattagttg aaattacacc tgattctata agacttagaa aaagattctt aaatgaacat
    31741 gatagattaa gatataacaa atctagacaa ggtaaataaa acgtacattt acctctaatt
    31801 aacaaaatag ccatatagta ctgaaaaatt atttcagttt atatggctat ttttatttga
    31861 aatttatatt attcaacatt tatataatta gctgcttgaa cggctgcaat agctccatct
    31921 gatgctgctg ttattatttg acgtaaaaac ttagttctac tatctcctgc tacatataca
    31981 ccttctactg atgttgtaca agactcatct gaaattatat atccaccttc atccaaatca
    32041 agaacatttt caaacatttt attattaggt ttaagaccta tagcaataaa aataccacta
    32101 acatctatag ttcttttttc ttcagtcttt aagtttttta cttctatttt cgatacagtc
    32161 ttttctcctt ctattttttc tacaccatga ctgtaaagta tctcaatatt ctctcttgct
    32221 ttcacagatt tctccaacac ttcttcacct ctaaaactat ctcttctgtg aattaaatac
    32281 acttttgtac aattattagc taaaaataaa gcatcttcta gtgcagtatt tcctccacct
    32341 actatagcaa cttctttatc tttaaaaaag gctccatcac atgttgcaca gtaagatact
    32401 cctctacctg taaattcttg ttcccctgca caacctaatt tacgtctttc aactccattt
    32461 gcaagaataa cagcctttgc tttatgttca cctgaagaag tttttacaac ctttactttt
    32521 ccctctaaat ttatctcttc aacctcatca aactgaatat caacaccttg agcaactgct
    32581 tgattgtata tattattaga aaattctacc ccagaaatct tttgaactgc tggataattt
    32641 tctacctcag aggtacttgc aacttgacct ccataaatat ttttttcaaa tactgtaacg
    32701 cttaaccctg ctctcatagc ataaattgct gaagttaaac ctgctggtcc agcaccaatt
    32761 acaatgatat ctaccataac gtttacctct ctttatatta ttatttctta tatattattc
    32821 tcatcattct tatactttac tattattatc catatatact ataaacaaaa cattattttt
    32881 tattaattaa ctttatttta catatatata aaaaaactgc aaataaaaat taacttttat
    32941 ttacagttct cacttattta tataattcaa aaccttattg gttatcattt acagtgtctt
    33001 ctaatatatt gctttctgat atatatgata gaattgaaag tccatacata accaaaacta
    33061 atgctgctgt tataagtact attcccatat ttaatacctc cttttgttta cagtatacta
    33121 ttattatgtg aaatatttat gaatttaatt tgaatatata tgtaatttca cactaacaat
    33181 ttcttcaaat taaacattat taactatata cttttgttga accaattatg attaatagtt
    33241 taaatattag cactatttac ttatatttat atgatatacc atataattac atttttcaaa
    33301 ttaaagtttt gtaaactttt tttgtaatat agtgtagtat aaaattgtaa tattacagat
    33361 atttaatagt tatcttttaa ttactttcat taaaaacagc ttcatcacta tgaaaatcta
    33421 ggtttttaaa cttttaaaaa agttaaaaaa atatttttct aatactcaat ttgattacaa
    33481 tttttttaca atttaaaaaa tattttttcc aaatttttat attaatactt gactttgtct
    33541 gttttataaa ctagaataat taataatatt aagaatattg aaaggcattg attaggaaga
    33601 gtaaatctga atcgattacc agagaaggaa actactagct gaaatgtttc cctaattaga
    33661 aggattgaaa actacctagg agcttctatc cgaagttatc ttaatgattt tagtaggaat
    33721 agacgttttt attacttgcg ttaaagtatc aagtggattt tttaaaatca atttgggtgg
    33781 aaccgcggga aacagattct cgtccctttt ttagggatga gggtcttttt ttattaccta
    33841 aattcagttt ttaaaatatt ctgtatctaa tttaattagc taattaaaaa tttaaaatat
    33901 atggaggatt ataaaaaatg tattattcaa gtacgagagg caccgaagaa aaagtaactg
    33961 catcacaagc aataataaaa ggaatatcaa atgatggtgg tctttatgtt ccaagtgaat
    34021 ttcccaatgt aaaaaatgaa cttataaatt tagtaaattt aacgtattct cagatagcat
    34081 tttttgtact tagtaaattt ttatgtgatt ttactgaaga tgaaattaaa aattgtatag
    34141 aaaatgcata tgatgaaaag tttgattgta gtagtatagc tccattaaat aaagtaaatg
    34201 atacttattt cttagaacta tatcacggtc caactttagc atttaaagat atggcactta
    34261 ctataatgcc tcatcttctt aaaacatcta taaagaaaga taatttagag aaagatgttg
    34321 tgattcttac tgctacatct ggagatacag gtaaagctgc acttgaggga tttaaagata
    34381 tagataaaat aaagataatt gtattcttcc cagaagatgg tgtaagccca gtacaaaaac
    34441 ttcaaatgaa aactcaaact ggaaaaaata catatgtagt tggtataaaa ggaaattttg
    34501 atgatgcaca atcaggtgta aagaagattt tttctgataa agaatttaat caaaaactat
    34561 tggataataa ttatatatta tcttctgcaa attcaattaa tataggaaga cttcttccac
    34621 aagttgcata ctatttttat tcatatatga aattagttag caatagtgat ataaatttaa
    34681 atgataaaat aaattttgtt gtcccaactg gtaattttgg taatattcta gctggatatt
    34741 atgccaaaca aatgggtctt ccaataaaca aattaatatg tgcatcaaat gataataatg
    34801 ttctttatga tttctttaaa actggtgtat atgataaaaa tagaacattg aaattaacta
    34861 cttctccttc tatggatata ttaatttcaa gtaatttaga acgattactg tttgaaatat
    34921 caaatagaaa tactgatatt gtaaataagc ttttatcaga ccttagtgat aaaggagtct
    34981 acaaaataag tgatgatatg gaaaaaaatt tagcctcatt ctatggagaa tattcaaatg
    35041 aagaagaagt taaaagcacg ataaacaatg tgtttaaaaa ttataattat ttgatagata
    35101 ctcatactgc tgttgcatac aattgttatg aaaaatataa aaaagaaact tctgataaca
    35161 caaaaactgt tattgtaagt actgcaagtc cattcaagtt ttctgaagat gttctaaagt
    35221 ctatagattg tgattttaaa gaccttgatg actttgctat aattgataga ttatcaagta
    35281 tttctaaaat agatattcca aaacctatta aaaatcttaa aaatgcagaa atactacata
    35341 aagatattta tgaaaaagat gaattaaaac tagctataaa aaaattctta aaggtatagg
    35401 tgattattat gttagagatt atagttcctg caacaagtgc taatataggt ccaggatttg
    35461 attgtcttgg aattgcgtta aatatataca ataaatttta tgttgaagaa attgaaagtg
    35521 gtcttgaaat agaaggttgt gaagatgctt acaaaaacga aaacaactta gtttatacat
    35581 ctatgaagta cttttttgat agagttaaac cagaaaaaat acctgctggt atcaaaataa
    35641 aaatccaaag tgaagtacct atatgtagag gtcttggcag tagtgcctct tgtatagtag
    35701 ctggagttat agctgcaaat gctctatcag gtgctaattt agataaaaat caattactaa
    35761 atatagcttc agaaatagaa ggtcacccag ataatgttgc tcctgctatt ttaggaaata
    35821 tgattgtatc tgttactgat aatgagaata tacattatga tattataaaa attcctgaag
    35881 aacttaaatt ttgtgcaatg atacctaatt ttaagttatc aacagaaaaa gctagaggtg
    35941 ttttaccaaa ggaaatacca tattctgatg gggtattcaa tgttagtaga gttgctttac
    36001 taatatctgc cttactaaac aaaaactttg acctacttaa agtagcttgt caagacaaat
    36061 tgcatcaaga ttatagagga actctaattg agaactacaa tgatattgtt gaaaaatctg
    36121 aacaattaaa tagtattgga gtatttttaa gtggagctgg acctactata atgtctttaa
    36181 taaaagaaaa tgatgatagt tttgtggata atatgaaaaa ttacctacaa aaactaaaat
    36241 ctgattggga aataaaagag ttatgttgcg attctaatgg agctgtttta aatataatat
    36301 aattatcgtc ttctatacaa aatataacta ctcttttatt ataatttgta gtataataat
    36361 taggactagg taataatatt aagtattata atctagttct ttaaacatgt ttacattgag
    36421 gagggattat cataaaagag ttaataatta gagatttagt tgcaaaagtt cctataattc
    36481 aaggtggaat gggcgttggt atatctaggt catcactagc tggtgcagtt gctaagcttg
    36541 gtggtgttgg tgtaatttct ggagttcaaa ttggatatga tgaggaagat tttgaaacta
    36601 atactataaa tgcaaattta agagctataa aaaaacatat ttctaaggcc aaagaaatct
    36661 caaatggtgg tattattggt attaatttta tggtagctat gaaagaatat gaaacatacg
    36721 taaaggaagc tgttaaagct ggtgtagacc ttataatatc tggagctgga ttacctaata
    36781 agctaccatc attagtaaag ggaagtaatg taaaaatagc acccatagtt tcaactgcaa
    36841 aagctgctaa tgtaatttta aaaatgtggg atagaaaaga gaaaactact gctgacttaa
    36901 tagttgttga aggtccaaaa gctggtggtc accttggata ctctaacgag gaacttgata
    36961 acatagattc tatagactat gataaggaat ttgttgaaat tttaaaggtt gcaaatactt
    37021 atggagaaaa atttggtaga aacataccag tagttgctgc tggtggtata acttctagta
    37081 gtgatgttaa aaaatatata gatatgggtg caagtggtgt acaagttggt acaagatttg
    37141 ttgctactta cgaatgtgat gcccatgaga actttaaaat ggcatacata aatgctagtg
    37201 aagaagatgt tcatatagtt aaaagtcctg taggtcttcc tggacgcgcc ataagaaaca
    37261 aatttataga agaagttaaa ataaatcgtc cagaaataaa gaagtgctat aattgtttga
    37321 ttccttgtaa tccaaaagaa actccttact gtatttctca agctctaatc aatgcagtta
    37381 aaggagatgt tgaaaattca cttttatttt gtggaaatga tgcctataaa attgataaat
    37441 taagtactgt tgaagatgtt atcaatgaat tgatttctga attataattt aaagaaaact
    37501 aaattaagat tttatcaagc taaggagttt aaatacgtta tttattaatc tttataaaca
    37561 tatttatgtc cttagctttt ttgtgtcaat ttccttttat tgaaatttta atttaattag
    37621 agatagtatt aacccttata actaatcttc ttttacaagt acattggtta tttcagctat
    37681 atataaagta tgataatctt tttgtggata ccatcttcca tctatacctt cagcaataaa
    37741 acattgaggt tcaagtttct gactatacat ttttttgcat ataatagcca ttttagattc
    37801 tttaaaataa ggtgtatcat ttaagtgttc tatattaaat ccaatctgtg atatcttatc
    37861 ctcttctcta ccagatacct ttccacaata tgaaagctct ttacgaaaat cttcatcaaa
    37921 aaatgtaaga gaaaatttat ctgtattatc tataaattcc ttagtataac gctgtggtct
    37981 tattactaca aaagcaacat cttttcccca cataactcca agccctcccc agctagcagt
    38041 cattgtattc actttacctt cattttctgc tgttataagt gtccaatctt tacctatcaa
    38101 tccaaatgga ttatttttaa tctcttctgc caaaatttct ttaaaatcac tcatatctct
    38161 aataacctct cattctctta tatttatatt ccttttattt tcgtgataaa ttataaatga
    38221 agtctagttt tgaaaataaa atactttttt aaatatatta ttgcaaataa gtaaatatat
    38281 atatactctc ttatttttta atatatttaa taatttcact cagaatatat atattcttta
    38341 ctcaaattaa atataactta tatactttat gtgtaaatta tggtaaaaat attatttaat
    38401 caaatcaaaa cttgatttat atacctggaa aaggtattat attaaagagt gcttaaaata
    38461 cgcatttcat aaatagctat atataaaata ataaataagg agagtgatgg gcaatggata
    38521 ctagtccgtt gcggagagaa ttttttacat tttcatcact taataatatc taaaatcaaa
    38581 actaatacat atattcagtt atataaatta gttaattaat agatactatt aaatgatgag
    38641 atttatataa aactgaataa aggatgtgtt gccatgataa gatattacaa aactatagat
    38701 tcaaaattag agaaacttag tttttttgaa gatggctgtt ggataaatct tgttgaacct
    38761 aatcatagtg aaatcaacga aatttctaat ttattaaata tagatgtaga aagcatagaa
    38821 tctgcactag atgaagaaga acgctcaaga atagatgttg aagacaatca tactcttata
    38881 cttatagata taccagtaga cgaaagtgac tctaattctt ctcattatac tacaataccc
    38941 ttaggtatta tactaactga agaagctatt gtaacagttt gtgatgcaca aactaagatt
    39001 ttaaatgact ttatagttgg tcatattaaa gattttttta catttaaaaa gactcgcttt
    39061 ttgcttcaaa ttcttcacaa aaatgcagct tattacttgc attacttaag aaaaataaat
    39121 aaaatgacaa taataataga gcgagaaatt tacaaatcaa tgaaaaacaa agaattggtt
    39181 caattattgg aattagaaaa atctttggta tacttctcta cctcactaaa atctaatgaa
    39241 cttgttttaa acaaaatggt tagaactgct ggtataaaga agtatccaga tgatgaagac
    39301 ctattagaag atgttatagt tgaaaataga caggctcttg atatggctaa aatatatgga
    39361 gatatattga gtagaattat ggatgctttc agtgcaatta taagtaataa tcagaataat
    39421 gttatgcaaa ttttaacagt agttacacta attttctcaa tacctacaat aatatcagga
    39481 ttctttggta tgaatgtcat caacatgcca ttttctaata acccaaacgg attttggata
    39541 atacttctta ttacctctat aatatgtata gtgattacat ttttcatgtc aagaaataag
    39601 ctattataaa atattaataa aaaagccatt agaattaatt gatttacatt tatcctaatg
    39661 gcttttatat atttaaatct atataatctt ataatacttt ttaactatca tgttcttcat
    39721 ctataatcat ttcagtttca agcccttcta gcattgaatc taaactttct tttatattta
    39781 gtatataaat tggtacatac tcttcttcat ctattacctc ttcttgcaac ttaaatggag
    39841 gaattaatac ttcatcaaag tctatattta aatttggaaa gccttctact atctcttcac
    39901 aattatcgta ctcttcattt gctaaagaaa tgtacatatc taggctcttt ttataataaa
    39961 gacctgcaag catatactca cacttcttac ttccatattt aataccttct ttataatatt
    40021 tctcagcttc tgcgtcatca tttaatttta aataaatttg acctaaatta tatattgatt
    40081 caacacaacc ttgtgctcta gccttttcat accaaaattt agaatttaca taatctttat
    40141 agaacatatc ataaattaat cctaccatat gttgagcata cacattattt tcattggcag
    40201 gtgtatcaaa catcatttta gactcttcca atttaccttc tctaaaataa attctaccta
    40261 gatgtatacg agcattcata tggtttttgc tacttgccat ttcaaaatac tttctagcat
    40321 tttttgtatt tcctaagctc tcatatatac accccaatct ataactagac ctcgtatctc
    40381 cattttcaga tgctttctta taccaactta ttgcttcttc aatattattt aaatcttcat
    40441 agatatttcc taatttgatt tgacaagata cattatttgg aatcctcgaa taatacgaaa
    40501 tcgctttttc tatatcttga ttctgataat ataaatcccc tagattttca agggaacttt
    40561 tgcatccaac agctatagca tcctcataat atttaatagc attttcataa tctttttctt
    40621 caaaatatat acctgccaga ttattttttg cttctgttat atcatcttca gcagccattt
    40681 tataataagt ttttgccttc tctatctcat tttctctatt atataaatta gcaagtctat
    40741 acttagaaag tgtatgattt ttttctattg ctttctcata ataataaatt gcatctccca
    40801 gctcttcttt tctatcatat acatatgcaa gcctatactc agacttcaca tcatctctat
    40861 cagcactctt tttataatac ttctctgcat cttctaaatt atcatttatt tccataatca
    40921 tacccaagtt aaagcaacct ttcatatgac ctgacttgta caactgttta tataaactta
    40981 ctgttgattt attatctttc ttttttccat ttaatattgc taaattatat tttgcatcat
    41041 catctaaaag cacagaacct tttttatagt attcatatgc ttcatcatct ttctccaaaa
    41101 aagtatataa tacccctaaa ttaaaacaag ctttacctaa attcttgtct gctgctgttt
    41161 ttaaccattt ttcacacctt acaaaatctt tcattttaaa atggcataca cctaaattat
    41221 tttgtgcttg taaataacct aaatttgcta tcttttcata ccaatatata gcatattcat
    41281 agccatctaa cttatagtac atattaccta aatcaaaagc agcatcttca cttccacttt
    41341 tatatgccat tgaataccac ttttctgctt ctttaaattg ttttttactt tcatatatat
    41401 ttcctaaagt atattgagat tttacgtaat tatccaatgc agcactctta tacaactcta
    41461 ttgcgctttc catcttaccc atcttttcaa ggagggcacc cttagtatgt acgactttcg
    41521 ggtcattaga tatatttttt atttttttta tagaaaattt tgtatttttc attattcgct
    41581 acctacccat tttataaaat atattctctc aaacattatt atacattata atctacaatt
    41641 aatgctataa tattgaattt ttaccttttg tcactatatt gtaacattaa attttaaatt
    41701 ttataatcat tagattttat tatgtaattg gtatataatg tatatatagg ggggacattt
    41761 tatgaatttc agcaatattt ttatccaagt tgcagtttta tttataatta ttttagttgg
    41821 atattttgtc agaaaattca acttattaga tgaccactgc acatctaagc tttcaacttt
    41881 gacaatgaca gtttttttac catcaatgat aattagctcc atgcaaatta actttgatag
    41941 taaaatgata caaaaaatac tattgttatt atttacatct ttgattatgt atatagtttc
    42001 aattataatt gcatttttat tgaaatacat tttaaaatgt aatgataaaa aagatttggg
    42061 aatataccag tatatagttg ttttttcaaa tgttgctttt atgggttatc ctgtaattga
    42121 agcagtttta ggtcatgaag caatattcta tactgcaata ttcaatttgc cttttaactt
    42181 attttctttc actttaggaa tttatctttt atctaaaggc agtacaagta gaggtttttc
    42241 aataaaatca cttataagcc ctgctacaat agctattgtt attggacttt ttttatttgt
    42301 aacaggactt aggttacccc aatttataaa cgagccactt gagatgttgg gaagtataac
    42361 tacaccaata tccatgatta tcattggaag cttacttgct aattcttcag ctctcgattg
    42421 ttttgtcaac aaaaaattat atatagtcac ttttataaga ttattggtac ttcctgtgat
    42481 tgtgtatttt attctaaaag gatggataaa tgataagatg attttagcta taccagtagt
    42541 aatttcttca atgcctgctg ctgcaaatac tgctataatg gctaatcaat atgactccaa
    42601 tataacacta gcttcacaat gtgtgttttt tacaacacta ttttcagtta tatctatacc
    42661 ttttataagt attttactct tatcttgatt tattttttta tgtattatat aataacatat
    42721 tcaataaatt acaaatataa acattttatt gtagtatatt gatggaattt tttcctagat
    42781 atttgtcaat aatatctata tgtattatag aataggaggc ttaaatatgg atatggattt
    42841 actctttaaa atagtatttg ctatagttgc tataggtgtt tctgtaaaaa tcattaaaac
    42901 tgttgctagt ttagctttta aaatagcgtt gatattgcta ataattttat ttgtatatag
    42961 aatgtttttg taaacattta aaaataagtt ttttaacaca atagagaagt aaaatagatt
    43021 atctttaatg taaatttttt attaaagaca ctctatttta cttctctatt agcttattta
    43081 aattaaattt ttattatatc ttcccataat ataaacatct tcaaattttc catctctgat
    43141 tacagcatat tttttagttc cctctatttc aaaacctagc tttttatata aatttaatcc
    43201 cttttcatta tccacaatta cttctaatcc tactctagtt aacataatcc aattatctgc
    43261 tatatctaaa agttgttcca taagcttctt acctactcct cttccctgat aattctctgc
    43321 aacacttatt cctatttctg cgctatgtct caatcgtgga gaagaattta catgtaaccc
    43381 agcaaaacct attacatctt tttctccatt attattagtt tcagctacaa acatataatc
    43441 attttctccc aaagaagcta acatagcttc agttttatcg actctgtcac tcattaatgc
    43501 caaagtattt ctcataacac tgtatgttct tctaatttca ttaaaagctt gtgcatcttc
    43561 tcttcttata ggtcttattg ttatatctat aggcttactc atattggatt ccccctcaaa
    43621 cataatcttt atttttaatt aaaattttac atctttattt tatactgttc aaatctatgt
    43681 atgcttctac ctgaggtaca tatatcatat tatcttttat atgtgtactt ccaaattctt
    43741 ttaattctgt accttcttta tccttagtta ttttatatct aatggattcc ataccttcaa
    43801 ctacttcagc atgaaaaaac ataccttcat attgtttaaa tctaaaatta aaattgtctt
    43861 tagtaagttt tattatcata tttttatcta ctccttatat aattgatatt tttcttatta
    43921 ttagttgtat atatactgct tattcatatt aatatattat aacttatcat ttatttagta
    43981 taaagttata aatagatata tttatactta ttttacaatc tttcttcaat tgatatataa
    44041 tatgtttata taaactaatg tatgtgaggt gaaatatgag caaaaaaaca aaatattttt
    44101 ctttaattct ctttcctatt gctttgcttt taaattttat agccagcaaa gttccaaata
    44161 ttgttgaaaa atattactcc caattcatag ataaaataat tgtacaaata ttgagtaaag
    44221 tttctggaat tttcccattt tctctctatg agattacaat gtacataata gttatatcta
    44281 tcttcttatt tttatgttgt actttatcta caatttttaa taagaaaaaa aaattaaaca
    44341 tatatttaaa aaattccatt ttaaatatat tatccattgt atcaatagtc tactttcttt
    44401 ttgtagtgct ttggggaata aactataata ggattccact agaaaccaca cttataaata
    44461 actataattt aaaaaacaat acctctatcc aatcaaaaca atatagtgtt aaagagctta
    44521 ctaaattata taaattcctt gtaattaaag caaatgaaac tagaaaactc acattacaag
    44581 ataaaaatgg tattgtaaaa tctaatacag attataatgg tgtcataaat agagctcaac
    44641 taggatacga taatatcttg gatatattac ctggtgttag tggtagttat tctaagccta
    44701 agtatattat ttcatcaaat ctaatgtgct atacaggaat aactggtata tactttcctt
    44761 ttacaggtga ggcaaatgta aatatagcaa tacctgactt atatattcct tgtacagttg
    44821 aacatgaaat ggcacatcaa aggggatttg ctagtgaaga tgaggctaat tttatagcgt
    44881 atcttacttc tataaaacac cccaatattg attttaacta ttctggatat attttagctt
    44941 taaattatac tgcttctgct ttaagtaagg ttgattataa tgcatatgtt gatatttctg
    45001 ctggcatttc agattctgtc cgtagagatt taaaaaatga aagtgaattt tggcaaaaat
    45061 atgaaggtaa aattaatgaa atttctaatg agtttaacaa ttcttactta aaagctaata
    45121 gcgttactga aggtactcag agttatggta aaatggttga tttattgcta acttattatg
    45181 aattatatcc atataactaa acactacaat tcaaaatttt attcatatac agctgatatt
    45241 aaatcagctg ttttctattt aaataaatta tttaacttca agcaatctta tataatttga
    45301 tagtacttat actatctgta taacatttca attctaacta ttttagttaa aacatttcta
    45361 ttatcttttt taataaatgt tttaactaaa atttttaaaa cataaaactt ccacattatt
    45421 tcactatcta tataaaaatc taaaaattca catataaaat tacataacta aaaaatcata
    45481 aatttataga aaacatatat tcaaaataaa aaagcatgta tcaaaacttg acacatgctt
    45541 ataatcttat gtatatatat cattttgtca caataaaaat ttacttgtaa cactgatatt
    45601 tttaaacaaa atagtcctta tttaattaaa ttaacattaa ttaaattcgt actcattttg
    45661 ctatcattaa acattactta tagtaatttt ctaatacact atttgaaact tccttccctt
    45721 gaaaactttt caaccaattc tcatatgctg agtttttcca tacactacca tcattaaatg
    45781 ttacttgttt tacacaagat ataatgtact ttacaccatg ctctccagtt gattgtttcc
    45841 atttatcaaa caatagaaag gcatcatttt gattcttacc tggtgctatt gcattttgct
    45901 ttgcatattc tttctccatt tgtttccatt ctttcaacca attttctacc catgccttgc
    45961 cttgttgttt ttcaaacata cttattatat cctgtggtgg tgattgttgc atttttctat
    46021 aagtatgtga atatgatttt ggagacacag gagatatgcc tgtaacaata ccatagtcta
    46081 caccagctgg gctaaatcca acacttccta cttcgccatc tgctgccaca ttttgagcat
    46141 cccaatatag ctcaagtggt tttccatttt tatcatatgc taagcatgta atttcataat
    46201 ccataattgc cttttcactg ctatttgtta agcttataac attgctaggc caatgatatg
    46261 gagtatcatc atactgtatt ttgctattat ttataaataa tggaatattc tcattataaa
    46321 caagaccttt actactttga atatctgata ccttctttgt gacagtactt accgtatttg
    46381 ctaagtatac atttgttttt tctgaattgg tcgtactaag agaaaatgtt gttgtcgttc
    46441 cagtaatcag caaagcaaca actaaaatag gtaagctaga tattttttta tatctcacaa
    46501 ttcttcacct ctttttctat taacttataa taaaacaatt taccaaaaca ttaaaatcta
    46561 tgttaacata atttaccaac tgttctagta actatatcct atcatagtta ctatcaagtt
    46621 tcaatactat tgatggaaat tttcactata ttaaatcttt ttttaatttt ataaatttac
    46681 aatatgattt aactcataca tatatagtca aattagaata taagtttctt acatttaatg
    46741 aagtttataa aataaaaaat gactagataa ttaaatactg taaataaaaa cttattacaa
    46801 aagtatttaa aaatctagtc aattaatata tatatgaatt gtatactata atttttcaat
    46861 ctcttctagc aactcatcaa ctaatttgtt accatcaatc attctaacta tttcaccctt
    46921 tttaaataaa agaccttcac ctttaccccc agcaatacct atatctgcct ctctggcttc
    46981 accaggtcca tttacagcac agcccataat tgcaacagtg atattttttt ccatactacc
    47041 aatcttttct tcaacctcat ttacaacact aattaagtct atattacatc taccacatgt
    47101 agggcatgat ataactttaa tcttatcatt taaaagtccc aaacttctta aaatctgttt
    47161 accaacaata acctcttcaa cagggtcgcc tgttaaagat attctaacag tatctccaat
    47221 tcctttaaga agaagtgctc ctacccctat agaagacttt attgttcctt tgtgaacact
    47281 tccagattct gtaattccaa tatgaagagg ataatcaact ttttttgata ttaattcata
    47341 tgcatcaaca gttttataaa tatcggatga ttttagagat ataactatat tatgaaaatc
    47401 taagtcttca agaatcttaa tatgtcccat tgcactttca actaatgctt cagcagttgc
    47461 agagccatac ttttttaaaa gttctttctc taaagaacct ccattaactc caattctaat
    47521 ttttaaattt ctttccttgc atttctcaac taccatctta actctctcta tacttccaat
    47581 attaccagga tttattctta ttccatccac accttgttct atagcttcaa gggctagctt
    47641 ataatcgaaa tgtatatctg caataattgg tatatttaca ctagacttta tctttgctat
    47701 atttttagca gctttaatat caggaacagc aactctaact atatcacaac cagcttcctc
    47761 taatctcttt atttgagcta ttgtagcatc tgcatctctt gtatcagtat ttgtcataga
    47821 ttgtatactt ataggatttt ctcctcctat ttttacagtt cctacactta cttctctcgt
    47881 ctttcttctc tcgtaactca tattccacct ctatatatta ttttatattg aatctcttta
    47941 aatattaaaa tattataacc tacatgtata ttataaatta aaaagctatc tagttaaata
    48001 agaataaatt tcatatataa aaattaattt attcttattt aaaactacat agcctatttt
    48061 cttaaaatct ctaaaaacta aatcattgaa ataatcttag tatatcttta tatgtgataa
    48121 aaagcataaa taacattaaa gctccaaaac caacaacatt tatcatgcct tctttatttg
    48181 ggtcgagttt tttaccacct ctaacagctt ctagtaacag cataagtatt ctccatccat
    48241 caagtgctgg tattggtaat agatttacta tacctaaatt taagcttatg acagctgcta
    48301 aatacactac atttatgatg cctgtacgag cagcatctga taccatacca ataacaccta
    48361 ctggtcctgc tacagcattg ccaatccctc ctggtacacg tcctgtaatc atttgaccta
    48421 gaaatgttag catctgtttt gtcatatcta cagtagtttt acatgcattt actattgacc
    48481 ccaaaaagtc tttttctctt tgtggttgaa tccctatttc atactttcca ttgttatttt
    48541 taggtgttac atttacaact ttatcacttc catctctagt tatactaagt tttaattctc
    48601 caccagaaga agtatttatt atatttgcaa cttcatccca agtcttaaca gaattaccat
    48661 taattttatt tatcttatct cctacttgaa gccctacagc ctgtgcagga gtatctggca
    48721 ttatctttcc taatttagtc gttggagaac ctatatacaa aaatactgga actaaaagta
    48781 ttgctgctaa tattatattg aatattggtc ctgctacaat agtactaaat ctttgtaata
    48841 tagacttgtt tccaaaagaa tttggactta tttgttcttc atcttcacct tccatgctga
    48901 catatccacc aattggaagt gctcttatag aatactctgt atcttttttt acactatata
    48961 tcttaggccc catacctata gaaaactcat ttactttgat accacttctt tttgcaaata
    49021 taaaatgtcc taactcatgt attaatacaa ttatactaaa tagtattaat gcggctatta
    49081 tagtcataaa ttcaccttcc tattttttta tcagatttgc aacataagct ctactccatc
    49141 tatctgtttc taagatttct tctaatgttg gttcacttat gctactatga acttctaaag
    49201 tcttctctat gtaatatggt atgtcataga aaccaatttt atcctctaaa aattcactta
    49261 ctaaaacttc atttgctgaa tttaaaacag aggaataagt tcctcccatt tttaaacact
    49321 catatgccaa ttttaaacat ggaaaagttt ctaaatctgg ttcttcaaaa gttaaagtac
    49381 taaattttga aaaattcatt ctttcaaagc tactttccat tctatctgga tatgtaagag
    49441 catactgtat tggtagtctc atatctggac atcctaattg agcaattatt gagctatctg
    49501 tatactgcac cattgaatga attatgcttt gtgggtgaac tactacatct atattttctt
    49561 gttctactcc aaataaccat ctagcttcta tcacttcaag tcctttattc ataagcgttg
    49621 aagaatcaat acttattttt cttcccatac tccaatttgg atgcttcaaa gcttcatttt
    49681 tagttatatt tgcaagttct ccctttttct ttcctctaaa tggaccacca gatgctgtaa
    49741 gtattatctt ttctatattt tttttatttt ctccatttag acattgaaat atagcactat
    49801 gttcactatc aacaggaaga atatttacat tgtatttttc tgcttctttc attacaagtt
    49861 caccagcagt taccaacgtt tctttattcg ctaatgctat gtctattccc ttctttatag
    49921 cacaaagagt tgggactaat cctatcatac ctactacagc agttaaaagg acatccactt
    49981 catcaagtga tgatattatt tttaatcctt ccattcctgc taaaacttct atttctatat
    50041 ttttaggcaa catttctttt aatttcaatg ctttattttc ctcaaaaact gttacatatt
    50101 taggtttaaa ctctactatc tgttctagca ataattcaat attactgtta gctgatattg
    50161 caactatctc aaacttatct ctattatctc taactacatc caaagtttgt ttacctatag
    50221 agcctgtaga acctaaaatt gatatctttt tcatataata atcctttcta ataataaata
    50281 taccctgtca aaacattata acactactaa aacaattatt tttactattc atagaaattt
    50341 catatattat tccacagatt aaaattaatc tattattttt tgtattttgt ggaatattat
    50401 aaaatattct agtattatta aatgctcttt tttatttcca caacatcttc tattttacag
    50461 tctagtgcta aacatatctt ctccattgta tccatagaaa cagatttatc atttcctagt
    50521 ctgcctaaaa cagaaatact tatacctgat atatttacaa attccatttt ctttattttt
    50581 ctgtcaatta acaatttcca taatggagcg tatgaaatca tgttatcacc tcgcaaaata
    50641 tattctatca cattttatct attttggaaa attttcatct attt
//
LOCUS       DAMKNB010000021        49440 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.022, whole genome shotgun sequence.
ACCESSION   DAMKNB010000021 DAMKNB010000000
VERSION     DAMKNB010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 49440)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 49440)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..49440
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.022"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            315..713
                     /locus_tag="PC494_001385"
     CDS             315..713
                     /locus_tag="PC494_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF3911890.1"
                     /translation="MDTLGKRIAYLRNSKKLTQRKLMDILKFENLGKYETGDRKPNCD
                     ILMSIADYFNVTTDWLLYGKEKVNVNSSVKEDKEDYLHVTNDEMTILNLYRQLNERDK
                     IKIEGILELKISEYKDLKKHSSNNNEDKMV"
     gene            complement(930..1139)
                     /locus_tag="PC494_001386"
     CDS             complement(930..1139)
                     /locus_tag="PC494_001386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3911891.1"
                     /translation="MCKLDSDGVIECCRAIDDFITALSNIKSLNMERLNTLTKYSSTC
                     SILLKEGNYEGCTIVYRKMLEELKT"
     gene            complement(1171..1380)
                     /locus_tag="PC494_001387"
     CDS             complement(1171..1380)
                     /locus_tag="PC494_001387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF3911892.1"
                     /translation="MDARKKWIPFLGVQVKQRLIELNMTQRELAKKIGVNENYLSAIL
                     NGRRTGKKYKSSIYQLLNIEYSEDD"
     gene            1679..2098
                     /locus_tag="PC494_001388"
     CDS             1679..2098
                     /locus_tag="PC494_001388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF3911893.1"
                     /translation="MDTLGERIVYLRKAKNLKQYELEEMLGCDNLSKFERNIRKPNYE
                     ILKSIAEIFNVSVDWLLNGDNLSHKSDLICDSSSNYPLNSINSNEIKLLNNFRKLNDY
                     DKAKIEGMIELKLHEYEKEKDLGKIEYNKNKDEKIDK"
     gene            2326..2781
                     /locus_tag="PC494_001389"
     CDS             2326..2781
                     /locus_tag="PC494_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3911894.1"
                     /translation="MGLRDKFAQSFARSKTMSGPEKKANEIMGKLLLKKAILPIVLMF
                     VIIIAGAMLKINSWVTLGINLVIAVGAFFYIRNSSKKYQNFKPYVGNLISLEKKGKKE
                     YVAIIKQGKLPVKLQIAYGGEDLEHVKKNQMVQISYNPDAKIAILVNRQ"
     gene            complement(3002..3262)
                     /locus_tag="PC494_001390"
     CDS             complement(3002..3262)
                     /locus_tag="PC494_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3911895.1"
                     /translation="MDKLITELSSLGAIGILCALLFKNTMQEKKEDRDMYKKTVENFI
                     ELSTQQQEINKNILVQMGIMKTDVEEIKEDVTGIKGMLQNGV"
     gene            complement(3525..3878)
                     /locus_tag="PC494_001391"
     CDS             complement(3525..3878)
                     /locus_tag="PC494_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3911896.1"
                     /translation="MFKFDKNKIEQIKQGRKVEMQYKDISDISIGQVKQDDDITNNFI
                     ANAEIYEMLLNQSSVNEASNISSFSVRKSGGESGMVEVYVALILRGKKTIEEVPAVIR
                     EQVRIRCKELEIPVE"
     gene            complement(3895..9216)
                     /locus_tag="PC494_001392"
     CDS             complement(3895..9216)
                     /locus_tag="PC494_001392"
                     /inference="COORDINATES: protein
                     motif:HMM:NF012632.1,HMM:NF024930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3911897.1"
                     /translation="MKRTKLLQRGNFFGDKNMVVDEFDEGYDNYDFINFFTGCCNYTF
                     GLKNNNILYGCGDNSNFQLGLGEDNTTRKLFTKIPNISTNIKKVACGESHAVILTSDG
                     ELLVAGINTDGQMGLGLEKVGKTVSTFEKVPEIKGVKDIACGLQSTYLLYNDGTLYVA
                     GNNLYGQLGLGTNGASANVNTFTKVDVDNVKAVFSYNKSAFIIKNDNKCYSTGFNNQG
                     QLGLGDKNNRDLFSLVSINDVKTIACGSEHTVLMTYNNDIYGCGKEKCFGNALQSSLF
                     TKIEEVNIKTIACGHGNTMLIDNKGTLKVAGNNDIYQLGIANYSENIDNSFIDLKNIV
                     AKNIFIGLSHSILIDSNNDSYCTGDNTYGQLGSFFDDMHIVEFKKMDSEKYSYSNYIN
                     LIKSEDKLTLLKEEMEIKDIELPLDIHSVRDVVFSPYCTLVILGNGDVYGLGNNRYKG
                     MGSDLPSQLNELTKLSISNVKSIVASKNISGGIFYIKNDDTCYYSGPNSNSIAGVLPS
                     NSDIFKKISIDNVKKVVINTDLSNWFSLIVTNNKQIYTSGKSSSYVNGLSNKSASQYT
                     EIGVSNVTDAYSSYNATFIVADEKKVYATGINTNYLLGVNPNDGVNINLTLINNWFYV
                     NPSGASYSTNSCTNDITKINNIIIYEYMAILCTNYGSFLTGYHGTLWTKPSDSTYRVQ
                     QQGITHAGYISNYIYNYYPTRCTQSSYSTNFAYLYYGESTSNLKNVNPDNLLISGGSS
                     YIHQYGRNYLNNQSSNNIAASNINSGPITSDKAIFLYKALLYLSSNTLYGFGNISESA
                     KELDVSDTQDGYNATNYKKVMKNIKNIFIPPYDLSRDKTRFAILTDKSLFICGYNSKG
                     THGISVNSSLNLNNKINYNKKNSSSEISSNIQEIYSHSKSTYLLTNNNMLYSVGLNDV
                     GQLGVGDEINRKVFTKINIDNIKSINVNRFTDNSKHVFAIKNDNTCYAVGLNNSGQLG
                     IGDNVNRNVFTKINVENVKYVAVYGNTSLLLTNDGLLYGAGNNGKGQLGLGDTTSRNI
                     FTRIPINGVRDVYICNDVSIIVKNDNTCYVCGFVNGYFGFTEGSISTFTKINIENVKS
                     VVTAGSEATFFITNDNVIYTTGKKERVFFSTETNDIKGIRVINNIINAKKIVVNGYTS
                     AILTNDNKLFVGGLSGYGSIANNNNTNSVEDVKDVFVTANNTLYIDNNNNLISSGRDT
                     YGISDESYRDMSVPYYKVSIKKDVDTVFSSYNTIFIKDIYGKFYSSTGDNRYNHLGIH
                     HRYDNDKNEALEGSLHSYFKTDNTSDKIVFNKKNEKLVMFNDKYIKTNNKYINYKNIF
                     KDNFKYTSIILPFEVSDIDISKTHSLAVAKDGKLYGIGSNSYKEINQTLEDIELLTLT
                     EVNISDVKKVACGDNYSYIIKTDNTLWSYGKNTEYQLGVGHNNDVRELQKVTGLPSVK
                     DISIYNSMTLVLTNEGELYAQGYNTNGLFGLGESEKDKIIRTFTKVLTNVKEIKSHND
                     DHILVIKNDNSLWITGKNKSMYKISISITDLYEFTKIPIPEHLNDILDIELSDDTIYM
                     ITKVDTSKASIEIVEKSISQVRVVVQDPNNVIEKLEMFINDELISTKTNLEINSIIFE
                     IPQNKIVLGENKILIKASSPTGDLYSSMFIFKSETGLKVKKDSILMINNKVYSIINIT
                     ENNTDLIVTLNEGLKDDMMENNPIYQLINKTKVQVKINKSDLFKDMKLVEIKKSDSSY
                     QEIYELEEANIKSAQPKIIVEKGDKWTAIKRPSMIFRYDAESNEPQA"
     gene            complement(9233..10216)
                     /locus_tag="PC494_001393"
     CDS             complement(9233..10216)
                     /locus_tag="PC494_001393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HDF3911898.1"
                     /translation="MEEKFYIILTKIGREKIANATALGELVGLTKFQVGDSNGEYYEP
                     TEEQTALKNVVWEGNINSLRIDEKNPNWIVIETILPGTVGGFMIREAAVLDNENNIIA
                     IGKYPETYKPRAEDGSIKDLVVKMILQLSNTSNVTLEVDPTLVFVTQKDIQDLDDKFD
                     KNIKEIKVKIGEELLSTEAKNLSGAINEVVEKIKNISIDDVIGGQIQTELSVLKNSYN
                     KLSEKVLDILIYLELESEIDVDEAGYWYDTLTNAKNIIAIEGLKLDLNRKCITGELGS
                     VTFKNVVLPFNANRVRYIHEMDNNFVETKSNRAYSIGQTDITLNKYSYEIR"
     gene            complement(10217..10915)
                     /locus_tag="PC494_001394"
     CDS             complement(10217..10915)
                     /locus_tag="PC494_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2313 domain-containing protein"
                     /protein_id="HDF3911899.1"
                     /translation="MKLIDKLPSFDRNYIVEEIQGAYDTELNILKEDIDDTFNQLFVD
                     TATWGLDMWEDILCIEKKELDFDTRRSNIKAKMRSRGTSTIEVIKSICEAYTKSETDI
                     KVYSDEFTFVLSFIANNCDYKTLLDCSDMIERVKPAHLLHYLEPIILDKSMVYCGGGM
                     VCSEEVKVHPYFEPIIKCSAVVNCGAGMISREEIKVYPLSIKCIENNCKINIAIANDT
                     GVENVVVYPKSEVV"
     gene            complement(10912..11964)
                     /locus_tag="PC494_001395"
     CDS             complement(10912..11964)
                     /locus_tag="PC494_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="baseplate J/gp47 family protein"
                     /protein_id="HDF3911900.1"
                     /translation="MYSDQTYEVIKNRTLENINLDIYKGEGSFLNNMVSGNNLELSKI
                     YLELSKMHKMAFIQDTYNQFLDKRVNEFGVYRKLGTESNGEVEFIGEKGTVINNGTII
                     SYRDLLFVVIKDVTIGSEEGDNSPVQALEVGKKYNLPTNCEFKLVDNISGVTKITNTR
                     SFEGGTDIETDEELKERFYKIQRNQATSGNKAHYEEWALEVDGVYNVKVYPRWDGPGT
                     VKVLIFGKNNQAVDTETIERCQQHIDEEKPIGPTITVVTPLPIEISISAVMKLEDGYT
                     LDNVKESFLESINTYFRDIRGEIIYTKVMGILINTTGVHDLSNLLINGSTDNITINED
                     KIPSVTTVNFSEVENQ"
     gene            complement(11957..12385)
                     /locus_tag="PC494_001396"
     CDS             complement(11957..12385)
                     /locus_tag="PC494_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2634 domain-containing protein"
                     /protein_id="HDF3911901.1"
                     /translation="MSTIFPFIGVPEDYILPKTEELPIFREVAWDFEKDEPILEKGDF
                     KIIEKKEALKVWIYKCIKTNRYEHEIYSLEYGTELSELIGQKYTKGLTESEASRFIKE
                     ALLINPYILEVNVKSANFNRDILSANVKVSTIYGEVEINV"
     gene            complement(12385..12711)
                     /locus_tag="PC494_001397"
     CDS             complement(12385..12711)
                     /locus_tag="PC494_001397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2577 family protein"
                     /protein_id="HDF3911902.1"
                     /translation="MANPINEFIGIIREEGKYHNQPSFFIGKIKSKLPDLKIETNNII
                     LEKEDILIDSWMIDRQLETFDTETNQEHQHEVKNPFIDNFESGDMVIMFRIGEKFAVV
                     SKLVSL"
     gene            complement(12727..14256)
                     /locus_tag="PC494_001398"
     CDS             complement(12727..14256)
                     /locus_tag="PC494_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HDF3911903.1"
                     /translation="MIINRSKDSSSNEISFVSKDMGFLLTQSEVSYNFKDKLVEDIAK
                     QVFAENRLSVGIIAKTNVKYTKMFIGVNGYDTIMSAYTEASKKTKKKYMIEANLDKFN
                     VIEKGTVTLSVMFEEGFNIINTTFSESMENVKNKVIVVDQYGSKISEKIDNEIFKEVN
                     VIMQKVIQQQENQDVDIDSEFNGIEKSCSLKGYGDVSCITGRGVKVKDSYTKLVGLFY
                     IDTDKHTWQNGEYQIELELNFQNLMDEKSAGQDEPKEESNLGGEDYAGGKEFTAEFTA
                     YCPRKEEGGDTDCRKKKLDPSKKTCAAPMVGKYEQTYYTKEFLNKHPLLNYGDEIQVI
                     TGVSGRDGVYKVNDVGPAITIEKNGTYHIDILFGNVEEASKFGRRKGKIIIGGYSGNV
                     SDKAKIVISEAKKHLGKPYKWGGNGPSSFDCSGLMVYCFKKVNVSLPRTSNQQSKKGK
                     KVEQKNLQAGDLVFFHNPVSHVGLYIGNGEFLHAPQKGDVVKISKLSSRRDFNTARRV
                     L"
     gene            complement(14538..14960)
                     /locus_tag="PC494_001399"
     CDS             complement(14538..14960)
                     /locus_tag="PC494_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3911904.1"
                     /translation="MEMWLRQAEDRFRFPVFPSSFSINGKAAVNSSSILKIGEIATFG
                     GVALKSISISSFFPNKDYTFCDYTGFPSPYDCVNKIEKWMKEGFILRFTITETNINME
                     VIIEGFSYEERDGTRDVYFTLDLKEYKRIKIPKVTPKQ"
     gene            complement(14960..17413)
                     /locus_tag="PC494_001400"
     CDS             complement(14960..17413)
                     /locus_tag="PC494_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3911905.1"
                     /translation="MGNVREEGINMYLTDNYTPKMNQIISVTDNFRRATVAVSLSTNV
                     MASSIKNSIGSASNRVNSLNSSLRKVQTTASSVSSTMTKLSSSINAVSGVIGSLNGSI
                     MRLAITIAMIIDYFNKLIQKKNEFNSNIMIILIFKAKSDEVEKTKNKLLGNLKKIGGK
                     IWNIVIKAKDMTKRVISSILGKLKQVEKRPYQGSINLKDMVSSAMGRILPKLMLFKNT
                     FWSGVIAIKDMASGIISKVFPKLRLFAGKVWSGAIAVKDMASGILGSIKGKISDLTNG
                     ATIGVAVKKGVDLLGQEQNQKVVLESVMKRNTGKVNQIDVDDYYGSLVRMANDTPFDP
                     EDVVAMGTKAKMISNITGGKKEKDITQAMVDVRALNMNTSSEQDVSAAFLSAAKGNME
                     SLNTLVGENYKTFDEALEGISVKQMGLAKEMSNTIPGIISGAQTSINNGLKSIVKPFD
                     DILGQGLKKIKTFIESGLGNLAGLSEKMAGKIGNVMNGKIIIGNKYDQMQSRSVKNGK
                     EFSDSTQYRISNEAEKRKMMVENKQERFENHAATMIGNAPKAIVNAGSTLLQNIDFTA
                     LIDSLLPVVNLVNNLLDSINNKSPIAQGLISIFGTIVTTAFQLIGPVVEAVSPIITRI
                     FTFLGEYAPQINNFIETLGVIWKTVWETLGPLLETGWKIIEPILGAFFNILDKVCKIV
                     KDICKWWQTMINKIKNGSITGTVLNLVEKSKKNYKDNPYAGTKAGDSGKAYSGKKGNN
                     AFGLNYVPYNDYQTRLHEGEMVLTKQEANQYRSRKNGGNINIAKLADTIVIREEADIE
                     KITSKLVASIQLAQLGGVL"
     gene            complement(17413..17580)
                     /locus_tag="PC494_001401"
     CDS             complement(17413..17580)
                     /locus_tag="PC494_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3911906.1"
                     /translation="MYYYWKKKGIRPSLFYAMDKGELKLIEAFFALEIEEEVEKMKHG
                     YGVCPLTGGGM"
     gene            complement(17607..18053)
                     /locus_tag="PC494_001402"
     CDS             complement(17607..18053)
                     /locus_tag="PC494_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HDF3911907.1"
                     /translation="MSENGLSKNINIVDLLLNSDTENLERPSTIVELKRLSTIFGQEF
                     KVMCRALTISKDEEIQNTCLKIDENMKTDIDLPEMQMLTIIEGVCDLDGKLLFKNKEL
                     MDKFKAPTPKELARKLLLPGEITNLYRILQDVMGYGKNAVIEEVKN"
     gene            complement(18167..18595)
                     /locus_tag="PC494_001403"
     CDS             complement(18167..18595)
                     /locus_tag="PC494_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tube protein"
                     /protein_id="HDF3911908.1"
                     /translation="MANMEARNVMSGTWGELWLDGNKVAEVKKFQAKMEFTKEDIIIA
                     GQMGTDTKYMGYKGKGSITLYHVSSRMHKLIGEKIKRGSEPRFVAISKLNDPDSYGAE
                     RIAVKNIAFDDLTLADWEVGVKGEIEAPFTFTEYDFLDII"
     gene            complement(18609..19673)
                     /locus_tag="PC494_001404"
     CDS             complement(18609..19673)
                     /locus_tag="PC494_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail sheath subtilisin-like
                     domain-containing protein"
                     /protein_id="HDF3911909.1"
                     /translation="MAIGLPSINISFKELATTVKERSARGIIAMVLKDAKALGLNEIH
                     EKEDIPVDLSAENKEYINLALMGNVNTPNKLLVYVIEGEADIQTALDFLETKEFNYLC
                     MPKAVEADKTAIKNWIIKLRDIDKVKVKAVLGKVVGNHEGIINFTTEDVLVGEKKYSV
                     DEFTSRVAGLIAGTPLSQSVTYTKLSDVVDIPKMTKVDAESRVNKGELILIKEAGAIR
                     IARGVNSLTELTAEKGEMFQKIKIVDTLDIIHSDIRKVIIDDYIGKVTNSYDNKCLLI
                     VAIKSYLEELEKSALIESDSTVEIDFEAQKSYLKSKGVDLSYMTLQEIKEANTGSKVF
                     LKAKIKVLDAMEDIDLSIEI"
     gene            complement(19678..20121)
                     /locus_tag="PC494_001405"
     CDS             complement(19678..20121)
                     /locus_tag="PC494_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3911910.1"
                     /translation="MLKYKEILETIIEILKKNFTESIFIDDESVQGSEGSCFFVSILS
                     VICTPVMLNTNNKDIVISIKYLPKPQSKSIRMYEISDELNKLFNRNIKVTDRKLNITK
                     LEQSIKKEESIYVLNFTFTLNYLDSVYEEDVVYENMKEINLNLGE"
     gene            complement(20370..20810)
                     /locus_tag="PC494_001406"
     CDS             complement(20370..20810)
                     /locus_tag="PC494_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3911911.1"
                     /translation="MENKKDILFKETDKRLHNYKYLDIKIKNINLDIKRCENEYSGCG
                     AMVYTEKTSNTYNISSSVENEVLKREERLRKLKMEKEDIEIEKEKIENALTCLNDIEM
                     EFFNLFYNSKTKNNMTYISMKLHLDRTSCYNLKKKMIFKLSEIL"
     gene            complement(20915..21112)
                     /locus_tag="PC494_001407"
     CDS             complement(20915..21112)
                     /locus_tag="PC494_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF3911912.1"
                     /translation="MFKNNLKYYRKCKGMTQIQLARKAGITNDYISQIERGIKNPGLL
                     MAKKISSILEQNIEEVFFIQL"
     gene            21281..21601
                     /locus_tag="PC494_001408"
     CDS             21281..21601
                     /locus_tag="PC494_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HDF3911913.1"
                     /translation="MFAKRLRELRKEFGLTQRELGEKVGVSQRVLGYYETENRFPDEH
                     ILNKLADVFNVSVDYLLGRTLVKENIDTVAAHRKNPHEELPEEAQEQLNDYIEFLLNK
                     YKKK"
     gene            21683..22189
                     /locus_tag="PC494_001409"
     CDS             21683..22189
                     /locus_tag="PC494_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3911914.1"
                     /translation="MNNLDKLFELASQEEIIIHYTTYIAGDLEGLYINKHGIKIISLL
                     SNLKQNSKKLTSILAEELGHHFTSLGYYVSSYNDYYTKIIIDKCENKALKWACEFLIT
                     EEDIINIINSGITCVYEMADILNVDITFFQKRLEFLSLKKQSLQLGNNKYLILTNLPY
                     FYIFDPIS"
     gene            22890..23645
                     /locus_tag="PC494_001410"
     CDS             22890..23645
                     /locus_tag="PC494_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HDF3911915.1"
                     /translation="MEKKVLATVGEKEITNIDIENALKSLDPYQAMQFKTEEGKKHLL
                     NDLVNQELFFLDAKEEKLDEEEIFKLEMKKIEENVLKQFAINKVLSSVNVTEDEKVKF
                     FEANKSSFSKPESATAKHILVDSDEKAKEILAQIKSEEISFEDAALKHSSCPSKDMGG
                     DLGTFGRGQMVPEFEEAVFSMAKGEVSEPVKTQFGYHIIKLEDLQESTESTFDEVKAE
                     VEKSLLYQKQNEVYGNKINALNAKYGNLVKYND"
     gene            complement(23788..24216)
                     /locus_tag="PC494_001411"
     CDS             complement(23788..24216)
                     /locus_tag="PC494_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HDF3911916.1"
                     /translation="MNILFFLTPKSEVAYIYEDYTIRQALEKMEYHKYSAIPIISKDG
                     KYVGTITEGDFLWTLKNDLNLDLKGLEDVPVTDINRKMDNSPVSINADIEDLVIKSLN
                     QNFIPVIDDQDTFIGIIKRRDVIGYCYEIIRGYKNLANDN"
     gene            complement(24637..24837)
                     /locus_tag="PC494_001412"
     CDS             complement(24637..24837)
                     /locus_tag="PC494_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HDF3911917.1"
                     /translation="MKTGVVKWFNNEKGFGFISVEGEGDVFVHFSAITGDGYKTLEEG
                     QSVEFEVVDGAKGPQAANVVRL"
     gene            complement(25020..26189)
                     /locus_tag="PC494_001413"
     CDS             complement(25020..26189)
                     /locus_tag="PC494_001413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidase domain-containing protein"
                     /protein_id="HDF3911918.1"
                     /translation="MGGVALKILKNKNKYIKGIMAFVFLSLATTAGVFLINDLSMKNM
                     EEKVMESANVEGDDVKDQYKLLLENLFDYRNKAILEKNENILKGLYETDKKFGLWAYE
                     NEVKKMKYLENWSSKQGVKFKDIKTRVKIKKIKEKEKDLYGIICSVSTEYKYSYENQK
                     DKENAFRIGTYHYLNVKIIDNQYVITKEWYTDPFADSLNLENIKSDDIRNYIGQQDGV
                     ELQLTDEQKKAIDYAHKYCGAAADEEHGMKFNPNYRDYNPEGGDCANFASQIMFESGR
                     FKKNSIWNYSERAGTKAWVNAQAFKNYALYSGRGSLIAKGSYEEVYKEAYNLRPGDFV
                     GYEKKGRITHVSTVTGLDSRGYPLVTCHNTDRMLVPWDLGWSDKSIRFHIIKINY"
     gene            26425..27246
                     /locus_tag="PC494_001414"
     CDS             26425..27246
                     /locus_tag="PC494_001414"
                     /EC_number="2.7.1.35"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine kinase"
                     /protein_id="HDF3911919.1"
                     /translation="MQKKVAAINDLSGIGKCSLSVAIPILSALKVQCCPFPTAILSSQ
                     TGYPEFTFLDFTDEMVKYSNVWKNLKVNFDSIYSGFLGSKHQIEIVANFINDYPNAFI
                     VVDPVMGDNGVMYPIFTEEMRQEIKELVKHSDLTTPNLTEACFLTGNDYTKSDYNRDE
                     LIYIAKSVSDLGPSKVVITGILEDDNILNLAYNRDNDHVFFTSVKYNNCSYSGTGDIF
                     TSILCGMLVNKHDLGVAVNTATDFIYKTINYTSQFDTDRNDGVMFENFLSDLTNI"
     gene            complement(27322..28710)
                     /locus_tag="PC494_001415"
     CDS             complement(27322..28710)
                     /locus_tag="PC494_001415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase"
                     /protein_id="HDF3911920.1"
                     /translation="MLGGKKSNNKKVEKLRTIFIKYLSLFFIMTISIVLLLMLSFSVL
                     LSSGVILPANYAEKQFNKYKEQIISSEKVTEDIIPSIYEYGVYTLDGNLISGTFNKKE
                     SKEVWNLMRDIEERHAYSESYIKFFKKDEVFIIKYKIVSEYSSPILRAYLPKPETLGM
                     IIFSIIFFIEIVILSKVFGKKFNIEMELLKNTTEKIEQQDLDFVVESSKIYEINNVLF
                     SMDKMKLALKDSLEKQWMLEENRKEQISALAHDIKTPLTIIHGNTDLLIEINENPELL
                     EYMEYISKGVTQIEKYINTLIDISKTENGYILNKEAISMSEFIKDVLVQIEALASTKN
                     LDVEFYKQDNLPKNITIDRELLFRAIMNIISNAIDYSPSQSKLYISVSVHNKYLKFVV
                     TDCGSGFSKADLSKATEQFYTGDLSRNSKSHYGMGLYIVNNIVQKHNGTLCIENSVKT
                     GGAMVTIEIPIV"
     gene            complement(28845..29603)
                     /locus_tag="PC494_001416"
     CDS             complement(28845..29603)
                     /locus_tag="PC494_001416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic immunity ABC transporter MutG family
                     permease subunit"
                     /protein_id="HDF3911921.1"
                     /translation="MRQLIRIFCSDLIKLKRNFIILMHICIALMGMGLFLWYYKVSGA
                     DNILKIVAYLQVIAIAFPLLSSVVCSMFVEQEYYAGNYKHMLTTSNPKYLTLISKYII
                     LVCLGFVATLVSVLGFKFGISKAYFTSSFYMISILILIGCNLFEYILHLFLSLRFGKG
                     TSIGVGIVEMLLSALLLTGLGSGIWQYFPCAWGVRFITIWSSFSSSKTVEYIKVESIK
                     AYQSTGLICGFVTILAFVILCIWFSKWEGKKSEE"
     gene            complement(29605..30321)
                     /locus_tag="PC494_001417"
     CDS             complement(29605..30321)
                     /locus_tag="PC494_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic immunity ABC transporter MutE/EpiE
                     family permease subunit"
                     /protein_id="HDF3911922.1"
                     /translation="MERFIRVEFQKMKGTFGMKLIWIVPVFCILLCGLGGGQNAAFNW
                     WYTTFLPGALTLISSLIVLKDEKSKYRGILPLPIEMKDVWTGKMIYCIICCFIASIIS
                     AIGVVFVGIIYKETISIGQNIIASILIILLFMWQIPLCMFLASKFGMFVTVLTNMFFT
                     IVGVAVFSTTEMWYMFPYSIPSRLMAVVLHILPNGLPVPEGSEFLNNAVILPGVLISI
                     VLFVLFALATRVWFNNREVK"
     gene            complement(30323..31030)
                     /locus_tag="PC494_001418"
     CDS             complement(30323..31030)
                     /locus_tag="PC494_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic protection ABC transporter
                     ATP-binding protein"
                     /protein_id="HDF3911923.1"
                     /translation="MSNYILQVKGVSKKFKEQMAVDNISLAIKSNSIYGLLGPNGAGK
                     STLLKMITGILNPTSGKIMFEGHRWTRKDLSNIGSLIESPAIYENLTARENLKVHTTL
                     LGLPDSRIEEVLETVDLRDTFKKRSGQFSLGMKQRLGIAIALLNHPKLLILDEPTNGL
                     DPIGIEELRELIRSFPKQGITVILSSHILSEVEQVVDEIGIISNGVMGYQGEVSKEQN
                     LEELFMKVVAENRKRGQ"
     gene            complement(31146..31682)
                     /locus_tag="PC494_001419"
     CDS             complement(31146..31682)
                     /locus_tag="PC494_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HDF3911924.1"
                     /translation="MNKIAVSFLIIATTLLSTACMDYSISAVELVDSKESAVVKKDED
                     AKEETTSKMINSKKTTKIPIEIISKDEKIVKYLQIDEESSLKDKLRLILDTLSNEYFN
                     GLDMEVEVKEKDNLVKINLIEPDKKSRVSWKDDYLNEQNIIYTINNIIKNVIQEEDNS
                     IWIEEVEIYYNGKLIELR"
     gene            complement(31784..32854)
                     /locus_tag="PC494_001420"
     CDS             complement(31784..32854)
                     /locus_tag="PC494_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 family beta strand repeat protein"
                     /protein_id="HDF3911925.1"
                     /translation="MNKKLAIFAAVLLVIGIIGTTWSGILVMPSLINFGLEKEAELNK
                     ENKLYQEKVNIDKLDIAVDNINVMIRKSSNEDVRVTTRGNNEFYKYSVTLQDKTLVVK
                     GERKSENKIKKIRSFDHLLNTSINSMFSRDYREIRIYVPNNVDINASSISSYLFISDD
                     VDSNNITYKTSSGGFSRAITENKVNRLENLNLISNSNLHLSTKSILGVKNVNIESESL
                     DISSENGDVFINNIEEYIPENVNIKEKIGRNSNYESEFYLYSDMPIAKFLDIEVPNSK
                     VRLDIPVNKYKFNCDIKSKEAIEEFNNDEEYDNDSYDYEHNEEHSNKYRNTREIKGLL
                     NKNLSNLEKEYTIKINSNSLEL"
     gene            complement(32847..33905)
                     /locus_tag="PC494_001421"
     CDS             complement(32847..33905)
                     /locus_tag="PC494_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HDF3911926.1"
                     /translation="MNLNKTEFLEILKDYLKKDFSESEVNDILRDYEEYFVDGLIEGK
                     SDMEIIASLGSPKSIAKELILQTKEKNIEEEKIINTDVLNDKFSKFKSDMKKGYSILK
                     DEAKEKYSKSKENIDGKIMNTDILNGKFSRFKSNVKKDYSILKDEAKEKYNKSKENIN
                     DKLTPSIEEGVGGLSRQVIKGLLVVLSLFLIVPAFAFVCAIVSATIALVCSLIAFVIL
                     IPFVIKFIAMVPDVMMFCIFATIAFVGLEILAWQILLFAIKLGKQLLNNYIHWIKRKN
                     IYIKANEKMEKRKKATLNDEDLNKDINENSYNNDYYNREEESIKETDEYNDDSINFEA
                     IYKDLEDIENKKGEDKHE"
     gene            complement(33892..34224)
                     /locus_tag="PC494_001422"
     CDS             complement(33892..34224)
                     /locus_tag="PC494_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HDF3911927.1"
                     /translation="MNTQFRKGVLEICVLALISKKDMYGYEIVHNISKVIDVNEGTIY
                     PILRRLTKDLYFETYILESNEGPARKYYRITSLGKENLSNLMEEWREFVKAVEILISE
                     DEGGNELE"
     gene            34423..35544
                     /locus_tag="PC494_001423"
     CDS             34423..35544
                     /locus_tag="PC494_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactosyldiacylglycerol synthase"
                     /protein_id="HDF3911928.1"
                     /translation="MKDDKTILILTAQFGAGHISAAKAVKECIIEKYSNYNVVIQNFI
                     NASIPMMNKPMVKLYENNTKYTPGLYNYYYYFKKSFDSRHDLSHKLYTPKLSEYIADI
                     NPDLIISTFPLAAACVNNFKIKNPDINIPTLTVITDVVDSMEWVFENTDLYFVPSPEI
                     KNRFFQKGINPDSIKVTGVPVDKRFQIESKELCCDKYRLLLLGGGRGLFDIDEDFMHW
                     IDEFIEEHSNSIEITIVTGKNKKLYDNLTHKKPLKNIKVLGFVNDMYNLIRECDLMLT
                     KPGGATIFEAIQSQTPVLVKMPKVGQEIENAKFIIDKGLGMIYSDDLDLKNIFYKLVS
                     NEFDSIINFMKKNLKEFKTVIHPEKIADYISELIDNHYS"
     gene            complement(35672..37570)
                     /locus_tag="PC494_001424"
     CDS             complement(35672..37570)
                     /locus_tag="PC494_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine synthetase"
                     /protein_id="HDF3911929.1"
                     /translation="MDSLLYVIEKDKHTNEELREILKSNKNIRFVSLMGVDLGGNATD
                     EKIPVELFLEDIDKFLESAIQTDGSSVELYNIATLNNAKVDLMPDKSCHWYVDYNMEY
                     IDEEVGLPVGTLKIPAFLIHDNKKVCSRGVLQKADKYFKKSMYEIFREYPHVINNIGI
                     DSVDDIEEIMLTAATELEFWVNTPEDKADLEKLYVSQSLKEQYWKRTHGIIRTCLEKS
                     LIILQKLGVNPEMAHKEVGGIQSSISIDGRTNHAMEQLEVSWKFSTPLQAADNELLVR
                     DVIEDVFTSHGLEVTFKAKPIHGVAGSGGHTHVGVSAKLKDGSIKNLFAPKDLKEDYL
                     SELGYGALMGLLYNYEVLNPIVTASNDGFNRLVPGFEAPVCIVTSLGHSYEIPSRNRS
                     VLVGLIRDMKNPKTVRFELRSPSPLSNTYLVIAGCYQTMLDGIKAAAKSGLSTKELEK
                     ELSKNVGEESFYLEKDRAYRDENDVFEHYSLEERNARFGIPPATVYENMKNLEIYASK
                     LKSLKQGDVFTDSIIESFKIGAIDKWQKKLKTRIIEAGIQKIRSIVKIHTKENMDALD
                     EVVWNSISDLKFNIMKDTLTRESLFTRVREAIENKDYQTASDLQIELKRSMEEIQQLY
                     MQYKKNIY"
     gene            37885..38661
                     /locus_tag="PC494_001425"
     CDS             37885..38661
                     /locus_tag="PC494_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease domain-containing protein"
                     /protein_id="HDF3911930.1"
                     /translation="MEYIIFDLEFNQGFDKKLNKTVSNEKCPFEIIQIGAIKLDSKFN
                     IIDTFNSYVKPTIYKDIHPFISRMTNIKSSDFNDSPTFPEVYNNFIKFISSQDPILCV
                     WGAGDLKELYRNINYHKLPSNSLPKSYINIQQHASKYFNNPAGKSIGLQNAISILELD
                     EKMSYHNALNDAYYTAKVFIKIYNPSIVPDIYLYTSIKPKTIRYSNKKRVDYDKLFDE
                     FRKILNRELTKDEKKIINLAYNMWKTNQFTLENVKQRKNK"
     gene            complement(38753..39505)
                     /gene="xth"
                     /locus_tag="PC494_001426"
     CDS             complement(38753..39505)
                     /gene="xth"
                     /locus_tag="PC494_001426"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HDF3911931.1"
                     /translation="MKFISWNVNGIRACVGKGFLDFFKEVDADIFCLQETKLQEGQIE
                     LDLPGYFQYWNYAERKGYSGTAIFTKKEPLKVMYGINIEEHDKEGRVITLEFEDFYFV
                     TVYTPNSQSELKRLEYRTRWEDDFIDYLTKLDNHKPVIVCGDMNVAHKEIDLKNPKNN
                     MKNAGFTKEEREKFSKLLDSGFIDTYRYFNPDKEGVYSWWSYRFNARKNNAGWRIDYF
                     CASKKLEDRLVSADIHTEILGSDHCPVELEIK"
     gene            complement(39666..40616)
                     /gene="galT"
                     /locus_tag="PC494_001427"
     CDS             complement(39666..40616)
                     /gene="galT"
                     /locus_tag="PC494_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-1-phosphate uridylyltransferase"
                     /protein_id="HDF3911932.1"
                     /translation="MKELRIDPITNDVVIFATDRLKRPLDTADIPNEDEETNEYDEEC
                     PFCKGNEAHATDALFEIDSEEGWLVKSVYNKFPIIDDMARDVYGVHEVMIESDKHNRS
                     FYNMSQKEFEDVFFMYRNRFRDLSKDDKVEYVSIFKNFLRKAGASLMHPHAQILSMSF
                     IPPEITNELLVSKEYYDSNKSSLYDDLIENEISLDRRVVYNGEAFLVLIPYATKYSGE
                     VRIIFKDKIEFGELNDNNIQELSTIFEKLFKKLYNINGYMPFNLCIHTHPTKIETKSY
                     FNVHMHIIPRKYNFGGFELGTNMYVSSMSPEDLTKKLKID"
     gene            41001..42197
                     /locus_tag="PC494_001428"
     CDS             41001..42197
                     /locus_tag="PC494_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HDF3911933.1"
                     /translation="MNYSNRVSAMQASPIRKLVPFAQAAKDKGIKVYHLNIGQPDIKT
                     PKGFFDAVKNFDSEVLEYATSEGIPELLEALQNYYKTYDMNFEKDELLVTNGGSEALL
                     FTMMAVCDPGDNLLVPEPFYTNYNGFGQSVNVEVNAVTTKAENGFHLPSKEEILSKVD
                     DKTKAIILSNPGNPTGAIYTKEELNILAEIAKEKDLWIIADEVYREFVYDGLEYTSCG
                     NLEGVQDRVIIIDSVSKRYSACGARIGSIACKNKGLIAQILKLCQGRLCVPTLEQIGA
                     VELYKTPVSYFKEVNEEYKKRRDVLYNELMKVEGVICKKPTGAFYIVAKLPVENAEDF
                     TIWMLKEFNKDNETVMVCPAEGFYATPGLGRDEIRLAYILNEKDLHRAATLLKEGLEQ
                     YVALQK"
     gene            complement(42532..42984)
                     /locus_tag="PC494_001429"
     CDS             complement(42532..42984)
                     /locus_tag="PC494_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HDF3911934.1"
                     /translation="MNYIVKDTISFLVKTFPKIYSSLYLEDLKKFAPDYNVNKTQLRA
                     LVFIKNYGVISMTDLCSKLNIEKGSLTSMVDDLTDKKYVTRKRDLVDRRKYLIDITEE
                     GDKIATDFMDKLSDGLGEKLSKLTEEDRKKYLEAINTLQYILNKEEFR"
     gene            complement(43295..44740)
                     /locus_tag="PC494_001430"
     CDS             complement(43295..44740)
                     /locus_tag="PC494_001430"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HDF3911935.1"
                     /translation="MIDNKYTTYSNPLTDRYCSKDMSYIFSPQFKFSTWRRLWVALAE
                     GEHELGINITEEQLDELRANIDNINFDEARKIEKEVRHDVMSHVKAYGLQCEKAKGII
                     HLGATSAYVGDNTDVIQMNEALKLLRVKLVNLINNLKEFALKYKDMPALGFTHFQAAQ
                     LTTVGKRACLWAQDLILDLEDLNYRIDNMKLRGVKGTTGTQASFLSLFEGDHEKVKEL
                     DKKICKKMGYHSSYAVSGQTYTRKLDYQVISILSGIAQSMHKMTNDIRLLQSLKELEE
                     PFEKNQIGSSAMAYKRNPMRSERIASLSKYIISESISPAMVQATQWLERTLDDSANKR
                     LAIPQAFMAADAILEIGINVTDGLVVYENMINRRVNEELPFMATETILMEAVKRGGDR
                     QELHEIIREYSMKAAYRVKHEGKDNNLIELIMNDDSFKMSKEEILSIMDPKNFIGRAP
                     EQVVEFVNEVVEPAIKDYKEDLGKVDVDLRV"
     gene            complement(44884..45792)
                     /locus_tag="PC494_001431"
     CDS             complement(44884..45792)
                     /locus_tag="PC494_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HDF3911936.1"
                     /translation="MYSTKILDDYEYETFNVFSTKLNPNTKHDYLSKVILFKEFLKGK
                     ELIYATKEDCKNFVDYIQTKYAKSTCEKIYSYLHSFYNFLKKEGYIDINPFRYVEKPT
                     VTRIKTKDDVLSIQEINKLIGILPKLNIRDRVIIVCLVTTGCLLNELVSLKWKDLMVD
                     ENDNSYVRLGKGRKERVVKLHPYFFKLLEDYRNYSGLPEVIIPSDDFIFTTQKSNSIT
                     DRNVRLIVKKALDLAGLSQYSARDFRHSFAAISLRLGADESDVKNQLGWSDKYYAIRY
                     KYVLNFVDSEIVDYLIEKDNLDINKK"
     gene            46049..46873
                     /locus_tag="PC494_001432"
     CDS             46049..46873
                     /locus_tag="PC494_001432"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HDF3911937.1"
                     /translation="METFSLLEIFKAVILGIVQGITEWLPVSSTGHMILVDEFIKLNF
                     SNTFISTFLVVIQFGSILAVLVIFFRKLNPFDSAKNIKQKKETVRLWLKVIIAVIPSG
                     VIGILFEDDIDRLFFNSTVVAIALIVYGIIMIGLEKRNKKPKYKDFSQVTYKLALCIG
                     LFQCLALIPGTSRSGSTIIGAVLLGTSRYVAAEFSFFLAIPTMLGASALKLLKAGFGF
                     TGFEWLILGVGSVVAFVVSIVVIKFFMDYIKKHDFKVFGYYRIVLGIVVLAYFFLL"
     gene            46913..47443
                     /gene="lepB"
                     /locus_tag="PC494_001433"
     CDS             46913..47443
                     /gene="lepB"
                     /locus_tag="PC494_001433"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HDF3911938.1"
                     /translation="MSVKKEIFDWIKSIAMAIVLAFVILQFIRPSIVSGESMYPTLDD
                     KDYLILNRISYKVGKPEKGDIVVFKTNLVDGETGKKKDLIKRVIATEGDRIKISNSKV
                     YVNGKLLNEPYIHNNYTSGDIDTVVPKGKLFAMGDNRENSNDSRFPDVGMVDEDEVLG
                     KVMVRLLPLDNIGKVD"
     gene            complement(47525..49306)
                     /locus_tag="PC494_001434"
     CDS             complement(47525..49306)
                     /locus_tag="PC494_001434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UvrD-helicase domain-containing protein"
                     /protein_id="HDF3911939.1"
                     /translation="MSQYININSQLDALKLKEFEKIFYENINEDVKVVPKVTPFKGIN
                     TDLLYVKDGRILFIKFMDTTEDIFFILEEELLEVMNEEYELLKLKMGQKNRNISYNYV
                     YIMPYVEVEETYEFEEFVNNNIIDKNKLQDIMNKGSLEEYLNDENDEINLNLFLLDIC
                     SEYYIINDKLHLNEKFKKISFYNDDYKYTATMMEDVQIKDVVSIKYGNTLIEGGSGIG
                     KTAIMLSRAIKLAKVYPHHKLVIFTHTKQLCNELRERIELLYKDNNNLEVHTFSSFIF
                     KLAKKFNLIVDYNMLKNDYEKTFNNLVKQAQNIIKNKNMFKAIFIDEAESFLEYEIDF
                     IREFLYKTKFIFNVCSCNSLNISNRLNIFKKLYNGIEFDDKIILSKNYRQAKEIVDFT
                     NKFSNNSNSYINELRPNTEFSTFFYTKALRGGNKSVDIIKVSDLDDQISSVIWEIEYL
                     ISKKGLDYSEVAIVYPYNKKKLKSGKTIYFQYMLKKALEEAKIPYICAEDNLTNISKK
                     VGTTIANIYAIKNLEYKAVIVCELEMLYNQTINDIEQDYQVNDFVGDLNKVYLAMSRA
                     TDYLSIVTTFNEEASDIIRLITESKDI"
BASE COUNT        16206 a         8089 c         5468 g        19677 t
ORIGIN      
        1 aatactattt ttctcttaat ctttttctct tttacagaca atcaaaaagc aatcttagtt
       61 tatcgaaata aatttataca atctattcat acaccccttt acatttatat aacaattaaa
      121 cctattgtta tatatacaaa tcaaaataaa ccatatattt tcaactataa tatgttaaaa
      181 tcatattatg agcatattaa tttaagcaaa atgtcattta gactttaatt tagtagtttt
      241 atattataaa tttatatatt tttaatttta aatgtcattt agacattact cataaaaaga
      301 aaggagtgta ttttgtggat actttaggaa aaagaattgc ttatttgaga aactccaaaa
      361 aacttactca gcgcaaactt atggatattt taaaatttga aaacttaggc aagtatgaaa
      421 caggagatag aaaacctaat tgtgatatac taatgtcaat agctgattat tttaatgtta
      481 cgactgactg gcttctctat ggtaaagaga aggtaaatgt caatagtagt gtaaaagaag
      541 ataaagaaga ttacttacat gttactaatg atgaaatgac gatattaaat ctatacagac
      601 aactaaacga acgtgataaa ataaaaatag aaggaatact tgaacttaag atatctgaat
      661 ataaagactt aaaaaagcat tcctctaata ataatgaaga taaaatggtt taaacataca
      721 taatttgata cgattttaca tcatctatta accttctttt tttgtagtat attactaaaa
      781 tatggatatt ggattattta aaaacaagta tagtctaatt tcaagcacat ttataatatt
      841 tagattatct tatccatatt ttagtttaag tactttgaaa aatataatac atctctatgt
      901 ataacttata ttcctaagaa atgcattact catgttttta attcttccaa catctttcta
      961 tacacaattg tacatccttc ataattcccc tctttaagaa ggattgaaca tgtactagaa
     1021 tatttagtta aagtatttaa tctttccata tttaagcttt ttatattact gagtgctgta
     1081 ataaaatcat caattgctct acaacactct ataaccccat ctgaatccaa tttacacaca
     1141 agaatattca cctactttat atactattta ttaatcatct tctgaatatt ctatattaag
     1201 taattgataa attgatgatt tatatttttt acctgttctt cttccattta aaatagctga
     1261 caaatagttt tcattaacac ctattttctt cgctaattcc ctttgagtca tatttaattc
     1321 aataagtctt tgcttgactt gcactcccaa aaaaggtatc catttttttc gagcatccat
     1381 ttatcaactt cctttctaag tgatttatat ttacttttat attattttag cttacacacc
     1441 ccctctattt agtatatatt tttaatatgt acacatatta agtatataaa tttatttaat
     1501 actaaataag attttttgat tactttgtgc taaaattagg atgtaaattc gtatcattaa
     1561 gttaattata aagtcatttt gaccttaagt caatgctttt tatgtcattt tgaccttaaa
     1621 tttgaaacta tttacatctt aaaaagtctt tttgacatta attgaatgga gagtgtttat
     1681 ggatacttta ggagaaagaa ttgtttattt gagaaaagca aaaaacctta aacaatatga
     1741 actagaagaa atgttgggct gtgacaactt aagtaaattt gagagaaaca ttagaaaacc
     1801 aaattatgaa atattaaaat ctatagctga gatatttaat gtttcagtag actggctatt
     1861 aaatggagat aatctatcac ataaatcaga tttaatttgc gattcctcct caaactatcc
     1921 acttaatagc ataaactcta atgaaataaa gcttttaaac aattttagaa agttaaatga
     1981 ttatgataaa gccaaaatag aaggtatgat tgaattaaaa cttcatgaat atgaaaaaga
     2041 gaaggattta ggaaaaattg agtataacaa aaataaagat gagaaaatag ataaataatt
     2101 tttatgttgc ttttgatacg attttacatc atttctttgt tctaatattt ttatttcatt
     2161 tattttcttt tttataattt tatgataaaa taattagtat attttgcttt acttgaatgt
     2221 aattatttat acaaaagtca aacataatat aaatgtagta aatttttagt ttcaagtaat
     2281 atctcgttat tataactaaa tatttattaa aattaggagg ataaaatggg cttaagagac
     2341 aaattcgcgc aatcatttgc tagatcaaaa actatgagtg gccctgagaa aaaggctaat
     2401 gaaataatgg gtaaattgct tcttaagaaa gctatattac ctatcgtttt aatgttcgtg
     2461 ataataatcg ctggagctat gcttaaaatc aattcttggg ttacacttgg cataaattta
     2521 gttattgctg ttggtgcttt cttctacata agaaattcta gtaaaaagta tcagaacttt
     2581 aaaccttatg ttggcaattt gattagttta gagaaaaaag gtaaaaaaga gtacgttgct
     2641 attataaaac aaggtaagtt accagttaag ttacaaatag cttatggtgg tgaagacctt
     2701 gaacatgtta agaaaaatca aatggttcaa ataagttata atccagatgc taaaatagct
     2761 attttggtta atagacaata atttaataaa aaaaaggagt tgtcttaaaa ttgatttttt
     2821 ctaatcaaat ttaagctcaa ctcctttttt aatttttata tattattttt atatattatt
     2881 tttattactt tttttaatta atatttttaa atatcaaatc cttctcaata aaatagggta
     2941 ctatctacaa tactacttta tcttttccta acaatatata atctggtgct actctttcat
     3001 gttatacacc gttttgtaac atacctttta taccagtaac atcttcctta atttcctcta
     3061 catctgtttt cattataccc atttgaacaa gtatattttt gtttatttct tgttgttgtg
     3121 tagataattc tataaaattt tctacagttt ttttatacat gtctctatct tcttttttct
     3181 cctgcatagt atttttaaat aatagagcac atagtatacc tattgcccct agactactca
     3241 attcggttat taatttatcc attatagcct cctattgtct aaatttttta tacttatagc
     3301 tttaattttt gttatattct tacatcatgc aatattatat tttcaggatt atcaatttaa
     3361 tcttctgtac tttaaattgt aggtgcaatt tatagattga ataaataata aatatatata
     3421 caatttctaa tataacaaaa aataagtaca aggcttactt attaaagtta agaccttgta
     3481 ctttacataa aaaaaataac taatacatag ttattctaaa tttactattc aactggtatt
     3541 tctaattctt tgcatctaat tctaacttgc tctctaatta ctgctggtac ttcttctatt
     3601 gtttttttgc ctcttaaaat taaagctaca tatacttcta ccattccact ctcacctcca
     3661 gattttctta cactaaaaga gcttatatta cttgcttcat tgacagaact ttgatttaac
     3721 aacatctcat atatttctgc atttgctata aaattatttg ttatatcatc atcttgcttt
     3781 acttgaccta tacttatgtc tgaaatgtct ttatactgca tttctacttt tctaccttgt
     3841 ttgatttgtt ctattttatt tttatcgaat ttaaacaatt ttcacacctc cattttaagc
     3901 ttgtggctcg ttgctttcag catcatatct aaaaatcata gatggacgtt ttatagctgt
     3961 ccatttatct cctttttcta ctatgatttt aggctgagca ctttttatgt tggcttcttc
     4021 taattcatag atttcttggt aacttgagtc tgattttttg atttcaacta gtttcatgtc
     4081 tttgaataag tcagatttat ttatttttac ttgaacttta gttttattta ttaattgata
     4141 tataggattg ttttccatca tgtcatcctt taatccctca tttaatgtta ctattaaatc
     4201 agtgttattt tcagtaatgt ttatgattga atatacttta ttgtttatca ttaaaataga
     4261 atcctttttt actttaagcc ctgtttctga tttaaatata aacatacttg aatataaatc
     4321 gcctgtagga ctactggctt taatcagtat cttattttct cctaatacta ttttattttg
     4381 tggtatctca aatataatgc tatttatttc caaattagtc ttagtagata ttaattcatc
     4441 atttataaac atttcaagtt tttctataac attattaggg tcttgtacta caactctcac
     4501 ttgagatatt gatttttcaa ctatttctat agatgcttta cttgtatcta cttttgttat
     4561 catgtatatt gtatcatctg aaagctctat atctaaaata tcatttagat gttcaggaat
     4621 tggtatttta gtaaattcat ataaatcagt aattgatata gatattttat acatagattt
     4681 atttttacca gttatccata gactattatc atttttaatt actagtatgt ggtcatcatt
     4741 atgtgactta atttctttaa cattagttaa tactttagta aaagttctta ttatcttatc
     4801 tttttcactt tctcctagtc caaataatcc atttgtattg tacccttgag cgtacaactc
     4861 tccctcatta gttaaaacaa gtgtcattga gttatatata cttatatctt taacagaagg
     4921 taatccagta accttttgta actctcttac atcattattg tggccaactc ccaattggta
     4981 ctcagtattc tttccatatg accatagagt attatctgtc ttaataatat aggagtagtt
     5041 atctccacaa gcaacttttt tgacatctga tatatttact tcagtaagag ttaataattc
     5101 tatatcttca agggtttgat taatttcttt atatgaatta cttcctattc catataactt
     5161 gccatcctta gcaacagcca atgaatgtgt ttttgatata tcaatatcag atacctcaaa
     5221 tggcaatatt attgaagtat acttaaaatt atctttaaat atgtttttat aatttatata
     5281 cttattattt gtttttatat acttatcatt aaacattact agcttttcat ttttcttatt
     5341 aaaaactatt ttatctgatg tgttatctgt tttaaaatat gaatgtaggg aaccttcaag
     5401 agcttcattt ttatcattat catatctatg gtgaatacct aaatgattat atctattatc
     5461 tcctgttgaa gaataaaatt ttccatatat atctttaata aatatagtat tgtaactaga
     5521 aaatacagta tcaacatctt tctttataga tactttataa tatggaactg acatatccct
     5581 ataagattca tcagatatac cataagtatc tctacctgat gatatcaaat tgttattatt
     5641 atctatataa agtgtattat tagctgttac aaaaacatct ttaacatctt ccacactatt
     5701 tgtattatta ttatttgcta tacttccata tccactaaga cctccaacaa atagtttatt
     5761 gtcatttgtt aaaatggctg aagtatatcc attaactact attttttttg catttataat
     5821 attattaatt actcgtatac cctttatatc attagtttct gttgaaaaga ataccctctc
     5881 ttttttccct gtagtataaa taacattgtc atttgttata aaaaatgtag cttcacttcc
     5941 tgctgttaca acagatttta cattctcaat atttattttt gtaaatgtac ttatacttcc
     6001 ttcagtaaac ccaaaatatc catttacaaa tccacataca taacatgtat tatcattttt
     6061 aacaattatt gatacatcat tacatatata cacatctcta actccattta taggtatacg
     6121 tgtaaatata ttcctacttg tagtatcacc caatcctaac tgtccttttc cattattacc
     6181 tgctccatat aaaagaccat cattagttaa taatagagat gtgtttccat atacagctac
     6241 atattttaca ttttcaacat ttattttagt aaatacattt ctatttacat tatctcctat
     6301 tcctaactga ccagaattat ttaaaccaac agcataacag gtattatcat tttttatcgc
     6361 aaatacatgt ttactattgt cagtaaatct atttacattt atagatttta tattatcaat
     6421 atttatttta gtaaatacct ttctatttat ctcatctccc actcctaatt gacctacatc
     6481 atttaaacca acactgtaaa gcatattatt attagttaat aaatatgtag acttcgaatg
     6541 gctatatatt tcttgtatat tagaagatat ttcactactg ctattctttt tattgtaatt
     6601 tatcttatta tttaaattta aactactatt aactgatata ccatgcgtac ccttagagtt
     6661 atatccacat ataaataagc tcttatcagt taatattgca aatctagttt tatctctact
     6721 taaatcataa ggaggtataa atatattttt tatatttttc attacctttt tataattagt
     6781 ggcattatat ccatcttgtg tatctgaaac atctagttct tttgcacttt cagatatatt
     6841 cccaaaacca tataacgtgt tagaagataa atacaataga gctttatata aaaatatggc
     6901 tttatcagag gtaataggac ctgaatttat attagatgct gcaatattat tagatgattg
     6961 attgttaaga taattccttc catattgatg tatataagat gaacctccag aaataagtaa
     7021 attatctgga tttacatttt ttaaattact tgttgattct ccataataca aataggcaaa
     7081 atttgtagaa tatgatgatt gtgtacacct tgtgggataa tagttatata tgtaattact
     7141 aatatatcca gcatgtgtaa ttccttgttg ttgaactcta taagtagaat cacttggctt
     7201 tgtccataaa gtaccatggt atccagttaa aaaagaacca taatttgtac ataatatagc
     7261 catatattca tatataataa tattattaat tttagtaata tcatttgtac aagaatttgt
     7321 actataactt gctcctgaag gatttacata aaaccagtta tttattaatg ttaaatttat
     7381 attgactcca tcattaggat taacacccaa taaatagttt gtatttatac cagttgcata
     7441 tacctttttt tcgtcagcca caataaatgt tgcattatat gaactatatg catctgttac
     7501 attgctaaca ccaatctcag tatattgact tgctgattta ttactaagtc cattaacata
     7561 acttgaactc tttccagaag tatatatttg cttattatta gttacaatta atgaaaacca
     7621 gtttgataaa tcagtattta taacaacttt ttttacatta tctatagata ttttcttaaa
     7681 tatatctgaa ttagaaggaa gaacacctgc tattgagtta ctatttggcc cagaataata
     7741 acaagtgtca tcatttttaa tgtagaatat tcctccagaa atattttttg atgctactat
     7801 agactttaca ttagagatac ttaattttgt caactcattt aattgacttg gtaagtcaga
     7861 acccattcct ttgtatctat tatttcctag accatataca tctccattcc ctaaaataac
     7921 cagagtacaa taaggactaa aaacgacatc tcttacagaa tgtatatcta gtggaagttc
     7981 aatatccttt atttccattt cttcttttaa taaagttaat ttatcctcag atttaattaa
     8041 atttatataa ttactataac tatatttttc actatccatt ttcttaaatt ctacaatgtg
     8101 catatcatca aaaaacgaac ctaattgtcc ataagtatta tctcctgtac aatatgaatc
     8161 attatttgaa tcaattagta tgctatgtga taaaccaatg aaaatattct tagctacaat
     8221 attttttaaa tctataaatg aattatctat attctcagag taatttgcta tacctaactg
     8281 atatatatca ttatttccag caacctttaa agtacctttg ttatctataa gcatagtgtt
     8341 accatgacca catgcaatag tttttatatt tacttcttct atcttagtaa atagtgatga
     8401 ttgaagtgca tttccaaaac atttttcctt tccacaacca tatatatcat tattatacgt
     8461 cattaacaca gtgtgttcag aaccacaagc tatagtctta acatcattaa tagaaactaa
     8521 actaaataaa tctctattat tcttatctcc taaacctagt tgaccttgat tattaaaacc
     8581 agtagaatag catttattgt cattctttat tataaaagct gatttattat atgaaaatac
     8641 agcctttaca ttgtcaacat ctacttttgt aaatgtattt acatttgcag atgctccatt
     8701 agttcctaga cctaattgac catacaaatt atttccagca acatataaag ttccatcatt
     8761 gtataaaaga tatgttgatt gaagtccaca tgcaatatcc tttacgcctt ttatttctgg
     8821 aaccttctca aatgtagaaa ctgttttccc tactttttct aatcccaatc ccatttgacc
     8881 atctgtattt atacctgcga caagtaattc tccatctgaa gtaagtataa ctgcatgaga
     8941 ttctccacat gcaacttttt taatattggt agatatattt ggtattttcg taaataattt
     9001 tcttgttgta ttgtcttctc ccaatccaag ttgaaagtta ctattatctc cacatccata
     9061 caagatatta ttatttttta gaccaaatgt atagttacaa catccagtaa aaaaattaat
     9121 aaagtcataa ttatcatacc cttcatcaaa ttcatcaact accatatttt tatcgccaaa
     9181 gaaattacct ctttgaagta gtttagttct tttcattata aaaacctcct aattatctta
     9241 tttcatacga atatttattt aaagttatat ctgtctgacc aattgaatat gccctattag
     9301 attttgtttc aacaaagtta ttatccattt catgtatata tctaactcta tttgcattaa
     9361 atggtagcac cacattctta aatgtaacac taccaagttc tccagttata cactttctat
     9421 ttaaatctaa cttaaggcct tctatagcta ttatgttttt agcattagtt aaggtatcat
     9481 accaatatcc agcttcatct acatctattt ctgactctaa ttctaagtat attaagatat
     9541 ctaatacttt ttcagataat ttattgtaac tattttttaa tacagatagt tcagtttgta
     9601 tttgacctcc tattacatca tcaatagata tatttttaat tttttctact acctcattta
     9661 tagctcctga taagttttta gcttctgtag ataagagttc ttcgccaatt tttactttta
     9721 tttcttttat atttttatca aacttatcat ctaaatcttg aatatccttt tgagttacaa
     9781 aaaccaacgt cgggtctact tctaatgtaa catttgaagt attggacaat tgtaaaatca
     9841 tttttacaac caaatcttta atactgccat cttcagcacg tggcttatac gtctctggat
     9901 acttacctat agctattata ttattctcat tatccagaac agcagcttct cttatcataa
     9961 atccaccaac tgttcctggt aaaatagtct ctataactat ccaattagga tttttttcat
    10021 caattcttag agaatttata tttccttccc aaactacatt ctttaaagca gtttgttcct
    10081 ctgttggctc ataatattct ccattactat ctccaacttg aaacttggtt aatccaacaa
    10141 gctctcctag tgcagttgca tttgctattt tttctctacc aattttggtt aatattatat
    10201 aaaatttttc ttccaattat accacctccg atttaggata aactactaca ttttctacac
    10261 ctgtatcatt tgcaatagct atattaatct tacaattatt ttcaatgcat ttaatgctta
    10321 aaggataaac ctttatttct tctctactta tcattccagc tccacagttt acaacagcac
    10381 tacattttat aattggttca aagtatggat gaacttttac ctcttcacta cataccatac
    10441 ctccaccaca atagaccata cttttatcta gtattattgg ttctaaatag tgtaataagt
    10501 gagcaggttt tactctttca atcatatcgc tacaatctaa aagagtttta tagtcacagt
    10561 tatttgctat aaaactcaat acgaatgtaa attcatcact ataaactttt atatctgttt
    10621 ctgattttgt atatgcctca catatacttt ttataacttc aatagtacta gtacctctgc
    10681 ttctcatttt agcttttata ttgctacgtc ttgtgtcaaa atcaagttct tttttttcaa
    10741 tgcagagtat gtcttcccac atatctaatc cccatgttgc agtgtcaaca aataattggt
    10801 taaaggtatc atcaatatct tctttaagaa tatttaattc tgtatcgtat gcaccttgta
    10861 tctcctctac aatgtaattt ctatcaaatg atggtagttt atcaattagc ttcattgatt
    10921 ttccacctca ctaaaattaa cagttgttac actaggtatt ttatcttcat taatagttat
    10981 attatctgta cttccattta taagtaggtt acttaaatcg tgtacaccag tagtatttat
    11041 aagtattccc attacttttg tatagattat ctctcctcta atatctctaa agtatgtatt
    11101 tatactttct aggaaagatt cttttacatt gtctaatgta tatccatctt ctagtttcat
    11161 tactgcactt atacttattt ctattggtaa tggtgtcaca actgttatag ttggtccaat
    11221 aggcttctct tcatctatat gttgctgaca cctttcaatt gtttctgtat caacagcttg
    11281 attatttttc ccaaatatca agaccttaac tgttcccgga ccatcccatc ttggataaac
    11341 cttaacatta tagactccat ctacttccaa agcccattct tcatagtgag ctttatttcc
    11401 acttgtagct tgatttcttt ggattttata aaatctttct tttagttctt catctgtctc
    11461 tatatctgta ccaccttcaa aacttcttgt gttagtaatc tttgttactc cagatatatt
    11521 atcaactagt ttaaattcac aatttgtagg taaattatat ttcttaccaa cttccagagc
    11581 ttgaactggg ctattgtcac cttcttcact accaatagtt acatctttta ttactacaaa
    11641 tagtaaatct ctatatgata ttattgtgcc attatttatt acagtacctt tctctccaat
    11701 aaattcaact tctccatttg actctgtacc taactttcta tatacaccaa attcattgac
    11761 tcttttatca agaaactggt tatatgtgtc ttgtataaaa gccattttat gcatctttga
    11821 aagttctaga tatatcttcg aaagttctag attatttcca gataccatgt tgtttagaaa
    11881 agaaccttct cctttataaa tatcaagatt aatattttca agagttctat tttttattac
    11941 ttcatatgtc tggtcactat acatttattt ccacctcccc atagatagtg gatactttta
    12001 catttgcact caatatgtct ctgttaaagt tagcactttt tacgtttact tctaatatat
    12061 atggatttat tagaagggcc tcttttatga atctactagc ttcactttct gtaagacctt
    12121 ttgtatattt ttgtcctatt agttctgaaa gctctgtccc atattctaaa gagtatatct
    12181 catgttcata tctatttgtc tttatacact tgtatatcca aacttttaag gcttcttttt
    12241 tttcaattat tttaaagtca cctttttcta aaataggttc atctttttca aaatcccatg
    12301 ccacttcacg aaagattggc aattcttctg ttttaggtaa gatataatcc tctgggacac
    12361 ctataaaagg aaatattgta ctcattataa gctcaccaac ttacttacaa cagcaaattt
    12421 ttcgcctatt ctaaacatta ttaccatatc cccagattca aagttatcta taaaaggatt
    12481 ttttacttca tgctggtgtt cttgatttgt ttctgtgtca aatgtttcta gctgtctatc
    12541 aatcatccaa ctatctatca aaatatcttc tttttctaat atgatgttat ttgtctctat
    12601 ttttaaatct ggtaatttac ttttaatttt tccaataaaa aaagaaggtt gattatgata
    12661 ctttccttct tctcttatta ttcctataaa ttcatttatt ggattagcca ttatatcacc
    12721 atccttttat aatactctcc tagctgtgtt aaaatctctt ctactactta acttacttat
    12781 tttaactaca tcaccttttt gtggagcatg taaaaattct ccattaccta tatataatcc
    12841 aacatggctg actggattat gaaaaaatac taaatctcct gcttgaagat ttttttgttc
    12901 tactttcttg ccttttttag attgttgatt tgacgttctt ggcaaactaa cattaacttt
    12961 tttaaaacaa tagaccatta aaccagaaca gtcaaaacta cttggtccat ttccacccca
    13021 tttataaggt ttacctagat gtttttttgc ttctgatatt actattttag ctttatcaga
    13081 tacattacca gaataaccac caataataat ttttcctttt cttcttccaa atttactagc
    13141 ttcttcaaca tttccaaata aaatatctat atggtatgtt ccattctttt ctatagttat
    13201 tgcaggtcct acgtcattta ctttatagac tccatcacga ccagaaactc ctgtaattac
    13261 ctgtatttca tctccatagt ttaataaagg atgtttattt aaaaactctt ttgtataata
    13321 agtttgctca tatttaccaa ccataggagc agcgcaagtt tttttagatg ggtcaagttt
    13381 tttctttcta caatctgtat ctccaccttc ttcttttcta ggacagtaag ctgtaaattc
    13441 tgctgtaaac tcttttcctc ctgcataatc ttctccccct aaattacttt cttccttagg
    13501 ttcatcctgt cctgctgact tttcatccat aagattttga aaattaagtt caagctcaat
    13561 ttgatattct ccattttgcc aagtatgttt gtctgtatct atataaaata gtcctacaag
    13621 ctttgtataa gaatctttaa cttttactcc tctaccagtt atacaactta catctccata
    13681 acctttaaga gaacagcttt tttctatccc attaaactcg ctatcaatat ctacatcttg
    13741 attttcttgt tgctgaatta ctttttgcat tattacattt acttccttaa aaatttcatt
    13801 atctattttt tcgctaatct tgcttccata ctggtctacc actattactt tattttttac
    13861 attttccatg ctctccgaaa aggtggtatt tataatatta aatccctctt caaacataac
    13921 acttaatgta acagttcctt tttcaataac attaaactta tctaaattgg cctctatcat
    13981 atactttttc tttgtctttt tacttgcttc tgtatatgca ctcattattg tgtcataacc
    14041 atttactcct ataaacatct ttgtatactt gacattggtc tttgctatta ttccaactga
    14101 aagcctattt tcagcaaata cttgctttgc tatgtcttca actaacttat ctttaaaatt
    14161 gtatgacact tcactttgtg taagtaaaaa tcccatatct ttagatacaa aactaatttc
    14221 attactgctt gaatctttag acctattaat tatcattcct ctaaagagtt ctttctcatc
    14281 tacatagaaa cagactgtac tagctattgg tatatcgatt tgttggaaat ttacatcaaa
    14341 tgatgattgt attattgaaa actctagtgt ccttgatgga gatttataat cacctgacca
    14401 tgataccttg tctactatgt cagttatgtc atatatactt ccgtttttta tgtgtaccca
    14461 aatcttaata ataaaaaatc acctgccttt tcatttaatt ctatcagcag ttatttataa
    14521 cttattatct ataatagtta ttgttttgga gttacttttg gtatctttat tcttttatac
    14581 tcttttaaat ctaatgtaaa atatacatct cgagtcccat ctctttcttc ataactaaac
    14641 ccttcaatta tgacttccat atttatattt gtttccgtaa ttgtaaatct taatataaaa
    14701 ccttccttca tccatttttc tatcttattt acacaatcat atggtgatgg aaaacctgta
    14761 tagtcacaga aagtatagtc tttatttgga aaaaaacttg atattgaaat gcttttaaga
    14821 gctacaccac caaaagttgc tatttcacct attttgagta tactagaaga gtttacagca
    14881 gcttttccat taatactaaa ggaagatgga aatactggaa atctaaatct atcttcagct
    14941 tgtctaagcc acatttccat tataagacac cccctaactg tgccaattgg atacttgcaa
    15001 ctaattttga tgttatcttt tctatatcag cttcttctct aatcactatt gtatcagcta
    15061 acttagctat gtttatattt ccaccatttt ttctgcttct atattgattt gcttcttgtt
    15121 tagttaaaac catttcacct tcatggagtc tggtttgata gtcattataa ggaacatagt
    15181 tcaatccaaa tgcattatta cctttcttac ctgaataagc tttaccagaa tcaccagcct
    15241 ttgttccagc atatggatta tctttgtaat tttttttact cttttccact agatttaaaa
    15301 ctgttcctgt gatgcttcca ttttttatct tattaatcat agtttgccac catttacata
    15361 tatctttaac tattttacat actttatcta atatgttaaa aaaagctccc aatattggct
    15421 ctataatttt ccatccagtt tccaacagag gtcctaaggt ctcccataca gttttccaaa
    15481 taacacccag tgtctctata aaattgttta tttgaggtgc atattcacct aaaaaagtaa
    15541 aaattcttgt gataatagga ctaacagctt caactacagg tccgattagt tggaatgctg
    15601 tagttactat tgtaccaaat atacttatta atccttgtgc aattggtgat ttattgttta
    15661 tactatctag taaattattt actaagttta ctactggaag taatgaatct attaatgctg
    15721 taaaatcgat attttgtaat agtgtacttc ctgcgttaac aattgctttt ggtgcattcc
    15781 ctatcattgt tgctgcatga ttttcaaaac gttcttgctt attttcaacc atcattttac
    15841 gcttttcagc ctcattagaa attcgatatt gagtagaatc agaaaactct tttccatttt
    15901 ttacacttct agattgcatc tggtcatatt tgttgccaat aattatctta ccattcatta
    15961 cattgcctat tttaccagcc attttttcag ataagccagc taaattgcct aatccacttt
    16021 ctataaaagt ttttattttc tttagtcctt gacctaaaat atcatcaaaa ggtttaacaa
    16081 tactcttcaa gccattgtta atgcttgttt gagctcctga tattatacct ggtattgtat
    16141 tactcatttc tttagctaac cccatctgct ttacacttat gccttccaat gcttcatcaa
    16201 aagttttata attttctcct accagagtat taagagattc catgtttcct tttgctgcac
    16261 ttaagaaagc tgctgataca tcttgttcac tacttgtatt catatttaaa gctctaacat
    16321 ctaccatagc ttgagttata tctttttctt ttttgccacc agtaatatta ctaatcattt
    16381 tagctttagt tcccattgca acaacatctt cagggtcaaa aggcgtatca tttgccattc
    16441 ttactaaact gccataataa tcatcaacat ctatttgatt aacttttcca gtatttcttt
    16501 tcattacact ttctagaaca actttctgat tttgttcctg accaagtaaa tcaacaccct
    16561 ttttcacagc gacacctata gtagcaccat ttgtcaaatc agatatcttc ccttttatcg
    16621 aaccaagtat tccacttgcc atatccttta cagctattgc accactccat accttacctg
    16681 caaataatct caatttggga aatactttac ttataatgcc acttgccata tcttttatag
    16741 ctattacacc actccaaaaa gtatttttaa acaacattaa cttaggcaaa attctaccca
    16801 tagcactact caccatatct ttaagattaa tacttccttg ataaggacgt ttctctactt
    16861 gttttaattt tcccaagata ctacttatca ctctcttagt catatctttt gcttttatta
    16921 cgatattcca aatcttgcca ccaatctttt ttaaatttcc aagtaattta tttttagttt
    16981 tttctacttc atcactttta gctttaaata ttaatataat cataatattt gaattaaact
    17041 catttttctt ttgaatcaac ttattaaaat aatcaataat catagctata gttattgcta
    17101 gtctcataat acttccattt aaacttccaa taactcctga aacagcattt atgctagaac
    17161 ttaattttgt catagttgaa cttacactac tagcagtagt ttgaactttt cttaacgagg
    17221 aatttaaact gtttactcta ttacttgcac ttccaataga attttttatg ctactagcca
    17281 ttacattagt ggaaagtgaa acagccacag ttgctctcct aaaattatca gttactgata
    17341 taatttgatt catttttggt gtgtaattat ctgtaaggta catatttata ccttcttctc
    17401 tcacatttcc cattacatac cacctcctgt caaaggacac actccatatc catgtttcat
    17461 tttttcaact tcttcctcaa tttctaaggc gaaaaaagct tcaataagct ttaattcgcc
    17521 tttatccatt gcataaaaaa gggacggtct tatacctttt ttcttccaat aatagtacat
    17581 tattgtagtc ctggtatccg tccctattag ttttttacct cttctatcac tgcattttta
    17641 ccataaccca taacatcttg aagtattcta tataagttgg taatttcacc tggtaataat
    17701 aattttcttg ctaattcttt tggtgttgga gccttaaatt tatccattag ctccttattt
    17761 ttaaataaaa gctttccatc caaatcacaa acaccttcta taattgtaag catctgcatc
    17821 tccggtaagt ctatatccgt tttcatattt tcatcaattt taagacaagt attttgtatt
    17881 tcttcatctt tacttattgt taaagctcta cacattactt taaattcctg cccaaatata
    17941 gttgataatc tcttaagttc aactatagta cttggtcttt ctaagttttc tgtatctgaa
    18001 tttaaaagta aatctactat gtttatattt tttgataatc cattttcact cattattatt
    18061 tgctccttta tcaatcaaat tcaatcaact aactttttta cttattaact atctgaattt
    18121 attaagtata tacttactaa atatcagtat aaaactaaat ataaaactaa attatatcaa
    18181 gaaaatcata ctcagtaaat gtgaaaggag cttctatctc tccttttact ccaacctccc
    18241 aatcagctaa agttaaatca tcaaatgcta tattttttac tgctattctt tctgctccat
    18301 aagaatctgg gtcatttaat tttgatatag caacaaatct aggttcagaa cctctcttta
    18361 tcttttctcc aattaacttg tgcattcttg aactaacgtg gtatagagtt attgagcctt
    18421 ttcctttata tcccatatac tttgtatcag tacccatttg acctgctatt ataatatctt
    18481 cttttgtaaa ttccatcttt gcttgaaatt tctttacttc tgctactttg tttccatcaa
    18541 gccaaagttc tccccaagta ccactcatta catttctagc ttccatattt gccatattaa
    18601 taatcctcct atatttctat tgataaatct atatcttcca tagcatcaag tacttttatt
    18661 tttgctttta aaaatacttt agaacctgtg ttagcttctt ttatttcttg taatgtcata
    18721 taagataaat ctactccttt tgattttaaa tacgattttt gtgcttcaaa atctatttca
    18781 acagtagaat cagattctat aagtgctgat ttttctaatt cttctaaata actttttata
    18841 gctactatca ataaacattt gttgtcataa ctgttagtaa cctttcctat atagtcatct
    18901 attatcacct ttcttatgtc actatgtata atatctaaag tgtcaactat ttttattttc
    18961 tggaacattt ctcctttttc tgctgttaat tcagttaaag aatttactcc tctagcaatt
    19021 cttatagctc ctgcttcttt aataagtata agctctcctt tattaaccct tgattctgca
    19081 tcaactttcg tcatcttagg tatatcgact acatcactaa gtttagtata agttactgat
    19141 tgacttaaag gtgtacctgc tataagtcca gccaccctgc ttgtaaactc atcaacactg
    19201 tatttctttt ctccaactaa cacatcttct gtagtaaaat taattatccc ttcatgattt
    19261 cctacaactt ttcctaatac agctttaacc ttaaccttat ctatatctct aagtttaatt
    19321 atccaatttt ttatagcagt cttatcagct tctactgctt ttggcataca tagataatta
    19381 aattccttag tctctaaaaa atctaatgca gtttgaatat ctgcttctcc ttctattaca
    19441 taaactaata atttatttgg agtgttaaca tttcccatca aagctaaatt tatatattct
    19501 ttattttcag cagataaatc aactggtata tcctcttttt catgtatttc attaagacct
    19561 agtgccttag catctttaag taccattgca attattcctc tagctgaacg ttctttaaca
    19621 gttgtagcta gctccttaaa tgatatgttg atacttggta atcctatagc catactatca
    19681 ctctcctaaa tttaaattga tttctttcat attttcatat actacatctt cttcatatac
    19741 actatccaga tagtttagtg taaatgtaaa gttcaataca taaattgact cttctttttt
    19801 aatactttgt tctagctttg ttatatttaa ttttctgtct gttaccttta tatttctgtt
    19861 aaatagctta tttaattcat ctgaaatttc atacattcta atactctttg actgtggttt
    19921 tggtaagtat tttatagaga taacaatatc tttgttattc gtatttaaca ttacaggtgt
    19981 acaaataact gatagtatac ttacaaaaaa acaagaccct tcagagcctt gcacactttc
    20041 atcatcaata aaaatacttt cagtaaagtt ttttttgaga atctcaataa ttgtttctaa
    20101 tatttccttg tatttaagca aataatcacc acactatcac taaatattct tgcttaatct
    20161 gataatctta ctataaatga tataagtcat ttttaaatat atatctcatt tattcctgtc
    20221 aagtatcttc tatattttta ggtaatatta ttcttttcaa tctatcacct ccttcaatat
    20281 ggatttcttt cacaataaca ttatctcaca tattttattg cctattgttg caatggtgta
    20341 tataaagtgt tgtaaaattg tcctattttt tataatatct cactcaattt aaatatcatc
    20401 tttttcttta aattgtagca agatgttcta tctaagtgta gtttcataga aatatatgtc
    20461 atattgtttt ttgtcttact attataaaaa agattaaaaa attccatttc tatatcattt
    20521 agacacgtta gagcattttc tatcttctct ttttctattt ctatatcttc tttttccatt
    20581 tttaattttc ttaatctttc ctctcttttt aacacctcat tttccacaga agagcttatg
    20641 ttatatgtgt tactagtctt ttctgtatat accattgctc cacatccaga gtattcattc
    20701 tcacatcttt ttatgtccaa gttaatattc tttatcttta tatccaaata cttataatta
    20761 tgtaatcttt tatctgtttc tttaaataat atatcttttt tgttttccat agtacttccc
    20821 cttttttata tacttattat tagcttcaaa tttacaataa tctctttagt gcacagtttt
    20881 ttactaatct cacaactttc aagaacatat tgttctataa ctgtataaaa aaaacttctt
    20941 ctatattttg ttctaaaata ctagaaatct tcttagccat aagaagtcca ggatttttta
    21001 tacctctttc tatttgagat atataatcat ttgtaattcc agcctttctg gcaagttgaa
    21061 tttgtgtcat acctttgcat tttctataat atttcaagtt atttttaaac attgttttat
    21121 acctccatta ctattaagaa tattttgttc ttcctcactt agattatata gaattatttg
    21181 ttctttatca atagatttta gaaaaaaata ttcttttata ttttattagt tttatttttt
    21241 agaacaattt gttataatct atacataagg tggtgttata atgtttgcca aaagattaag
    21301 agaacttaga aaggaatttg gattgactca aagagaactt ggagaaaaag taggcgtttc
    21361 ccaaagagtc ttagggtact atgaaacaga aaacagattt cctgatgaac acattttaaa
    21421 taaattggct gatgtattta atgtatcagt tgattacctt cttggaagaa ccttagttaa
    21481 ggaaaatatt gatacagtag ctgcacatag aaaaaatcca catgaagagt tacctgaaga
    21541 agcacaagaa caacttaatg attatataga atttttacta aataaatata aaaaaaaata
    21601 aaccatatga tgagcagtct atttttctgc tcttttaata taatttaaag gcaaacatac
    21661 attctatttt agggggattt ttatgaataa tttggataag ctttttgaat tagcttctca
    21721 agaagagata ataattcatt ataccactta tattgcaggt gatttagaag gactatatat
    21781 aaacaaacat ggtattaaaa ttatatcatt actcagtaat ttaaaacaaa actcaaaaaa
    21841 attgacatcc atcttagctg aagaacttgg acatcatttc actagccttg gatactatgt
    21901 atcctcttat aacgattatt atacaaaaat tattatagat aagtgcgaaa ataaagcctt
    21961 aaaatgggct tgtgagttct taattactga agaagatata ataaacataa ttaactctgg
    22021 catcacttgc gtttatgaaa tggcagacat acttaatgtg gatattactt tctttcaaaa
    22081 aagattagaa tttctatcat taaaaaaaca gtctttacaa cttggaaata ataaatattt
    22141 aatattaact aatttgccgt atttctacat atttgatcca atttcataat aaaaatagta
    22201 gtaattttaa ctggcttaac agtaaaatct atatatttat tttaacaaat tttggtttct
    22261 ataaattcaa tattaatata taataatgat atcatattat ttaaaattct aaaaacaaat
    22321 atatgctttt gttaagaaag gttgtttgat gaatgtataa agaaaagttg tttgataatt
    22381 attttaagtt cttagcacta ttattttggc caattatgtg gtataagtgg atagtaattt
    22441 caaatggtac tcttgaaaat atgttattta ccatatatgc aatcgtcgca attgttttca
    22501 tcattttata ttcggtgttt atgataaaat ataaagacat tacacaaata gatttctttt
    22561 acaggataag tactctactt gcttttatat ttacactttt tagcttttta atatacccaa
    22621 agagtttatt tttcttgtat ttaaagatta tttttactgg aatatacctt tattattcaa
    22681 tagtaaaaac tcttaaattt aaagatgacg aaggtgtagt gggtattatg agctcacttt
    22741 tattaattgt aataactttg ttctactaaa tttaattcta tttgacttaa tatggcttta
    22801 aatattagac atctacatta ttttctgata ttatttaaga tggtagtctt atattaataa
    22861 tgaaatacac tatgaaggag ttaactatta tggaaaaaaa agttttagca acagttggag
    22921 aaaaagagat aactaatatt gatattgaaa atgcattaaa atcattagac ccttatcaag
    22981 ctatgcaatt taaaactgaa gaaggaaaaa aacacttatt aaatgattta gtgaatcaag
    23041 aattattctt cttagatgct aaagaagaaa aattagatga agaagaaata tttaaattag
    23101 aaatgaaaaa gatagaagaa aatgtattaa agcaatttgc tataaataaa gttttatcta
    23161 gtgttaatgt aacagaagat gaaaaagtaa aattctttga agctaataag agctctttct
    23221 ctaaaccaga aagtgcaact gctaaacata tattagtaga tagtgatgaa aaagctaaag
    23281 aaatacttgc tcaaataaaa tcagaagaaa tatcttttga agatgcagct cttaaacatt
    23341 cttcttgccc atctaaagat atgggtggtg atttaggaac attcggtaga ggacaaatgg
    23401 ttcctgaatt tgaagaagct gtgttctcta tggctaaagg tgaagtaagt gaaccagtta
    23461 aaactcaatt tggataccat ataataaaat tagaagacct tcaagaaagt acagagtcta
    23521 catttgatga agttaaggct gaagttgaaa aaagtttatt atatcaaaaa caaaatgaag
    23581 tttatggaaa taagataaat gctcttaatg ctaagtacgg aaaccttgta aaatacaacg
    23641 attaatcata aggtcatata taaaaaagct gtcttttcac aatatttatt agaaaagaca
    23701 gctttttata ttaaagttta aatattcagt ttcatattat cattttttta ttgtaaagaa
    23761 ctcagcttaa aagtttaaat aagattttta attatcatta gctaaatttt tatatccacg
    23821 tattatctca taacagtaac ctattacatc tcttcttttt attatcccaa taaatgtgtc
    23881 ttggtcatct ataacaggaa tgaaattttg atttaaagat tttataacta aatcttcaat
    23941 atctgcgttg atggaaacag gagaattatc catttttcta tttatatctg tcactggaac
    24001 atcttccaat ccctttaagt ccagatttaa atcatttttt aatgtccata aaaaatcacc
    24061 ttctgttata gttccaacat atttaccatc cttacttatt attggaattg cagagtattt
    24121 gtgatattcc attttttcta gggcttgcct tatagtgtag tcttcatata tatatgctac
    24181 ttcacttttt ggtgttagaa agaataatat gttcattaca ctacccaccg ttactgaaaa
    24241 cttataaata ttactcaata tttataatgt tacttttttg cagtaacttt ctcctttctt
    24301 attttctaag tattcttaat actatacgct gtaacaagcg tttttccttt gctcatttta
    24361 atcttattat gctttattaa tatttttata tggtctataa gtatcactta ttctcttttt
    24421 agaaaattta ctaaaaatta attgacttaa acttagccat aataatttta ctctacacta
    24481 ttaattttaa catatttatc tcattattaa tgattttatt ttaataattt taatttattt
    24541 tgctattaat tttatttaca aaaactgaaa aaaccgctaa atgattagcg gcttatctct
    24601 catattacta gaacactaat atatatgaat ttttaattat aatctaacta cgttagcagc
    24661 ttgaggacct ttagctccat ctactacttc gaactcaacg ctttgtcctt cttctaatgt
    24721 tttgtatcca tctccagtta tagctgagaa atgtacgaaa acatctcctt caccttctac
    24781 agatatgaat ccaaatcctt tttcgttgtt aaaccattta actacaccag ttttcattaa
    24841 taaatcctcc taaaaaaaca caaatattta gctactcttt tctgtaacct tattactact
    24901 ctatcatata tagctatgtt tgtcaattat tattattttt atacattaat aatcaatttt
    24961 tttactttat aattttaaat gattattatc ttttacactt tatttttctt tataattttt
    25021 taataattta tttttattat atggaatctt atggacttat cactccagcc taaatcccat
    25081 ggcaccaaca ttctatcagt attatggcaa gttaccaaag gatatcctct tgagtctaat
    25141 cctgtcactg tcgaaacatg tgttattctg cctttcttct cataaccaac aaaatcccct
    25201 ggacgtaaat tataagcttc tttgtatact tcttcatagg aacctttagc aattaatgaa
    25261 cctcttccac tatacagtgc ataattttta aaagcttgtg catttaccca tgcttttgta
    25321 cctgctctct cgctataatt ccaaattgag ttctttttga accttccact ttcaaacatt
    25381 atctgtgatg caaagtttgc acaatctcca ccttctggat tataatccct atagtttgga
    25441 ttaaatttca taccatgttc ttcatcagct gcggctccac agtatttatg tgcataatct
    25501 atagcttttt tttgttcatc tgtaagctgt aactctacac catcttgttg accaatataa
    25561 tttcttatat catcagattt tatattttct aaatttaaag agtctgcaaa agggtctgta
    25621 taccactctt tagttatgac atattgatta tctataattt ttacatttag ataatgatat
    25681 gtacctattc taaaggcatt ttctttgtcc ttttgatttt catatgaata cttatattca
    25741 gtggatactg aacagattat accatagagg tctttttctt tttcctttat ttttttaatc
    25801 ttaacccttg tctttatgtc tttaaatttt acaccttgtt tactagacca gttttctaaa
    25861 tatttcatct tttttacttc attttcataa gcccacagac caaatttttt atccgtttca
    25921 taaagacctt ttaaaatatt ttcatttttc tctaatattg ccttatttct gtagtcaaat
    25981 aagttttcaa gcaatagttt atattggtct tttacatcat caccttcaac atttgcagat
    26041 tccatgactt tttcttccat atttttcata cttaaatcat tgattaaaaa tacacctgct
    26101 gtagtagcta aagacaaaaa tacaaatgcc attatacctt tgatgtactt attcttattt
    26161 ttcagtattt tcaaagctac acctcccaaa tagtacacct tacaaatcaa attacaaaga
    26221 atattctgtc acatatagta attttcatat ttaataattc tctattttat tatgtccaat
    26281 attaaaaatt aattgtatca atacactgtt ttttttacaa ttttttattt tataatctac
    26341 ttttttcttt tttttatagt aatatatatg tatataaata ttttggtatc attataatta
    26401 atacatacta atggagggtt ttttatgcaa aaaaaagtcg cagcaattaa tgacttatct
    26461 ggaataggaa aatgctcatt atcggttgct atacctatac tttcagcatt aaaggttcaa
    26521 tgttgtccat ttccaacggc catactttca agtcaaactg gttatcctga atttactttc
    26581 ttagacttta ctgatgaaat ggtaaaatat tcaaatgttt ggaaaaattt aaaagtcaat
    26641 tttgatagta tatatagtgg ttttttgggt tcaaagcatc aaattgagat agtggctaat
    26701 tttataaacg attatcccaa tgcttttatc gtagttgacc ctgtgatggg tgataatgga
    26761 gttatgtatc caatattcac agaagaaatg agacaggaaa ttaaagaatt agttaaacat
    26821 tcagatttaa ctactcctaa tttaacagaa gcttgtttct taactggaaa tgattatacc
    26881 aaaagcgatt ataatagaga tgagcttata tatattgcaa aatctgtatc tgatttggga
    26941 cctagcaaag tcgttattac tggtatatta gaagatgata atatattaaa tttggcttac
    27001 aatagagata atgaccatgt attctttaca tcagtcaaat ataataattg ttcttacagt
    27061 ggaactggag atatattcac atctatactt tgtggtatgt tagtaaataa acatgatttg
    27121 ggagtagcgg ttaatactgc aacagatttt atatataaaa ctataaatta cacatctcaa
    27181 tttgatactg atagaaatga tggagttatg tttgaaaact ttttatcaga tttaaccaat
    27241 atataaaatc aaaaaaacta tccattttat aaatacctat aaatcataaa atttaggtat
    27301 ttacaaaatg gatattattt actaaactat tggtatttca attgttacca tagcaccacc
    27361 agttttcaca gaattttcaa tacataaagt cccattatgt ttttgtacaa tattatttac
    27421 aatatagagt cccattccat aatgagattt agaatttcta ctcaaatctc ctgtataaaa
    27481 ctgttctgta gcttttgaca aatctgcttt agaaaaacca cttccacaat ctgtaactac
    27541 aaattttaag tatttattat gtactgatac acttatgtat agtttactct ggcttggtga
    27601 ataatctata gcatttgaaa ttatattcat aatagctctg aataacagtt ctctatctat
    27661 agttatattt ttaggcaaat tatcttgttt ataaaactcc acatctaagt ttttagtact
    27721 agctaatgct tctatttgca ctaaaacatc ttttataaac tcactcatac tgattgcttc
    27781 tttatttaat atatagccat tctctgtttt tgatatatct attaaagtat taatatattt
    27841 ttctatttga gtgacaccct ttgagatata ttccatgtat tctaataact caggattttc
    27901 atttatttca attaataagt cagtatttcc atgtataatt gttagtggtg tttttatatc
    27961 atgtgccagt gcagatatct gttcctttct attttcttct agcatccatt gtttttctaa
    28021 agaatctttt aacgccaact tcattttatc catagaaaaa aggacattat taatttcata
    28081 aattttacta gattctacaa caaaatctaa atcctgttgt tctatttttt ctgtagtatt
    28141 ttttaaaagc tccatttcaa tattaaattt cttgccaaat acttttgata atataacaat
    28201 ttcaataaaa aatattatac taaaaataat catacccaat gtctctggtt ttggtaaata
    28261 tgctcttaaa attggagaac tatactctga tactattttg tattttatta taaaaacttc
    28321 atctttctta aaaaacttta tataactttc tgaatatgca tgcctttctt caatatctct
    28381 cattaaattc catacttctt ttgattcttt tttattaaag gtccctgaaa ttaaattccc
    28441 atccaaagta taaaccccat actcatatat acttggaatt atatcttcag ttactttttc
    28501 acttgaaata atctgttctt tatatttatt aaattgtttt tctgcataat tagctggtaa
    28561 aattacacct gatgataata atacagaaaa tgataacatt aaaaggagta caattgaaat
    28621 tgtcataata aagaataaag ataaatattt tataaaaata gttcttaact tttcaacttt
    28681 tttgttgtta gattttttac ctccaagcat ttgtaccctg tcctccaata gtttaattaa
    28741 ttcataatta atacccaacc agttttttat ttgattattt tatatctttt tattgctaag
    28801 ttatatttta acataataat ataaataaac agtcaatttt tactctattc ttctgatttt
    28861 ttaccttccc atttagaaaa ccaaatacat aaaattacaa atgctaaaat tgttacaaaa
    28921 ccacaaatta aacctgttga ttgatatgct tttattgatt caacctttat atattcaacc
    28981 gttttagaac ttgaaaaaga cgaccaaata gttataaatc taacacccca tgcacaagga
    29041 aaatactgcc aaataccaga acccaatcca gttaataata atgctgaaag taacatttca
    29101 actataccta ctccaattga tgttcctttt ccgaacctta aacttaagaa taaatgtaat
    29161 atgtattcaa ataaattaca cccaattaaa attagaattg aaatcatata aaagcttgat
    29221 gtaaagtaag ccttagatat accaaattta aaacctaata cagacactaa tgttgctaca
    29281 aaaccaagac atactaagat tatatattta cttataagag taagatattt tggattagat
    29341 gttgttaaca tatgtttata attccctgca taatattctt gttcaacaaa cattgaacac
    29401 acaacacttg acaataaagg aaaagctatt gctataactt gtaaatatgc tactatcttt
    29461 agtatattat cagctcctga aaccttataa taccataaaa acaatcccat ccccattaaa
    29521 gcaatgcaaa tgtgcattag tattataaaa tttctcttta attttattaa atcagaacaa
    29581 aatattctta ttaactgtct catattactt cacctctcta ttattgaacc aaacccttgt
    29641 agctaaagca aataatacaa ataaaacaat agatattaat actcctggca aaataacagc
    29701 attatttaaa aattcacttc cctctggtac aggaagacca tttggcagaa tatgcaatac
    29761 aacagccatt aatcttgaag gaatcgaata tggaaacata taccacattt ctgtagttga
    29821 gaaaacagca actccaacaa tagtaaagaa catatttgtt agaactgtaa caaacatacc
    29881 aaattttgaa gctaaaaaca tacaaagagg aatctgccac ataaatagta aaataattaa
    29941 tatacttgca atgatatttt gacctattga aatagtttct ttatagatta tcccaacaaa
    30001 aactacacct attgcagaaa taattgatgc tataaaacaa caaataatac agtaaatcat
    30061 ttttccagtc caaacgtctt tcatttcaat tggcaatggt aaaataccac gatatttact
    30121 tttttcatct tttaatacta ttaaagaaga tattaatgtt aatgctcctg gaagaaatgt
    30181 cgtataccac cagttgaaag cagcattttg ccctccacct agtccacaca aaagtataca
    30241 aaacactgga actatccata tcaacttcat tccaaaagtt cctttcatct tttgaaattc
    30301 cactctaata aatctttcca tattactgcc ctctctttct attttcagct acaactttca
    30361 taaaaagttc ttctaagttt tgttcttttg atacttctcc ttgataaccc attactccat
    30421 tagaaattat tcctatttca tctacaactt gttcaacttc agacaagata tggcttgata
    30481 aaataactgt aattccttgt tttggaaaag aacgaatcaa ttctctaagt tcttcaatac
    30541 caatagggtc aagaccattt gtaggctcat ctaagattaa aagttttggg tgatttaata
    30601 atgcaatagc aataccaagg cgttgcttca tgcctagaga gaattgacct gaacgctttt
    30661 taaaggtatc tcttaaatct acagtctcta aaacttcttc aatgcgagag tcaggaagac
    30721 caagtaaagt agtatggact tttaaatttt ctcgtgctgt taaattctca tatatagcag
    30781 gagactcaat aagagaacca atatttgata aatcctttct agtccatcta tgtccctcaa
    30841 acattatttt tcctgaagtt ggatttaaaa tcccagttat catttttaat aaagtagatt
    30901 tcccagctcc atttggtcct aataatccat atatagaatt agatttaatt gctagtgaaa
    30961 tgttatcaac tgccatctgc tccttaaatt ttttagaaac tccttttacc tgcaaaatat
    31021 aattactcat aattttcatc ctttcttttg tcaaacttat ttacaagaat cattctaaat
    31081 cataaatata aggattttat aagaattaaa aaacaaaaaa agatgtgtta aaaacacatc
    31141 tttttttatc ttaattctat taattttcca ttgtagtata tctctacttc ttcaatccaa
    31201 atgctattat cttcttcttg gatgacattt ttaataatat tatttatagt atatattata
    31261 ttttgttcat tcaaataatc atctttccaa gaaactctac tttttttatc tggttctatc
    31321 aagtttattt taacaagatt atctttttcc ttaacttcta cttccatgtc taaaccatta
    31381 aaatactcat ttgataatgt atctaagatt aatcgcagtt tatccttaag tgaactttct
    31441 tcatcaatct gtaagtactt tactattttc tcatcctttg aaattatctc tataggtatt
    31501 ttagtagttt ttttagaatt aatcatttta ctagttgttt cttcttttgc atcttcatcc
    31561 ttctttacaa ctgctgattc tttagaatca actagctcaa ctgcactgat gctataatcc
    31621 atacatgccg tactcaataa agtagtagca attattaaaa aacttactgc tattttattc
    31681 ataagtatcc ctctcctaat tctctttcga tacttattat accatagtat agattatatt
    31741 tttatacttt taaatcaatt tataaattat tatagtaaat tatttacaat tctaagctat
    31801 ttgaatttat ttttatagta tattctttct ctaaattcga cagattttta ttcaaaagcc
    31861 cttttatttc cctcgtattt ctatacttgt tgctatgttc ttcattatgt tcataatcat
    31921 atgaatcatt gtcatattct tcatcattat taaattcttc aattgcttct tttgacttta
    31981 tatcacaatt aaatttatac ttatttactg gtatatcaag tcttacctta gaatttggaa
    32041 cttctatgtc caggaactta gcaattggca tatcagagta caagtaaaat tcactttcat
    32101 aatttgaatt tctacctatt ttctctttta tatttacatt ttcaggtata tactcttcta
    32161 tattattgat aaatacatct ccattctctg aagatatatc caatgactct gattctatgt
    32221 ttacattttt aacgcctaaa attgactttg ttgatagatg aagattgcta ttagatatta
    32281 agtttaagtt ttctaatcta tttactttat tttctgttat agctctgcta aaacctccag
    32341 aagaagtttt atatgttata ttatttgaat ctacatcatc agatataaat aagtacgaac
    32401 ttatacttga tgcatttata tctacattat ttggtacata tattctaatt tctctataat
    32461 cacgtgaaaa catactattt atagatgtat ttaataagtg gtcgaaactt ctaatctttt
    32521 taattttatt ttcagatttt ctttcgcctt ttacaactaa agtcttatct tgtagggtta
    32581 cactgtattt gtaaaattca ttattccctc ttgttgtcac acgcacatct tcatttgaac
    32641 tttttcttat cataacattt atattgtcaa cagctatatc taacttgtca atatttactt
    32701 tttcttgata aagtttgttt tctttgttta attcagcttc cttttctaaa ccaaagttta
    32761 ttaggcttgg cataactaaa atccctgacc atgttgtccc tattatacct attaccaata
    32821 aaactgcagc aaatatagca agttttttat tcatgtttat cttctccttt cttattttct
    32881 atatcttcaa ggtccttata tatcgcctca aaatttatac tatcatcatt atattcatca
    32941 gtttctttta tgctttcttc ttctctattg tagtaatcat tattatatga attttcatta
    33001 atgtctttat tcaaatcttc atcatttaaa gtagcttttt ttcttttttc catcttttca
    33061 tttgccttta tataaatatt ttttctcttt atccaatgta tataattatt tagtaattgt
    33121 ttacctagtt ttatggcaaa taataaaatt tgccatgcaa gtatctcaag ccctacaaat
    33181 gctatggttg cgaaaataca aaacatcata acatctggaa ccattgctat aaatttaatc
    33241 acaaatggaa ttaatataac aaaagcaatt aatgagcata ctaatgcaat agtagcagat
    33301 acaatagcac atacaaacgc aaatgctgga acaattagaa ataaagataa cactactaat
    33361 aaccccttta taacttgtct ggataatcct cctacacctt cttctatact tggtgtaagt
    33421 ttatcattta tattttcttt tgatttattg tacttttcct tagcttcatc tttcaagata
    33481 gaataatcct tttttacatt tgatttaaat ctactaaatt taccatttaa tatgtctgta
    33541 ttcattattt ttccatctat attttctttt gatttactat acttttcttt tgcttcatct
    33601 tttaagatag agtaaccttt tttcatatct gatttaaatt tactaaactt atcattcaaa
    33661 acatctgtat ttattatttt ttcctcttca atattttttt ctttagtttg taagataagt
    33721 tcttttgcta tagattttgg tgagccaagt gatgctatta tctccatatc actctttccc
    33781 tctataagac catctacgaa atactcttca taatctctca atatatcatt aacttcgctc
    33841 tcagaaaaat ctttttttag ataatccttt aaaatttcaa gaaactcagt tttattcaag
    33901 ttcattacct ccctcatctt cacttattaa aatctcaaca gcctttacaa attctctcca
    33961 ctcttccatc agattggata aattctcttt tcctagtgaa gttattctat agtattttct
    34021 agcaggacct tcattagatt ctagtatata tgtttcgaaa tacaaatctt ttgtaagtct
    34081 tcttagaata ggatatattg ttccttcatt tacatctatt actttagaga tgttatgtac
    34141 tatctcatat ccatacatat ctttcttaga tatgagagca agtacacaaa tttctaaaac
    34201 accctttcta aattgtgtgt tcatatactc catcctttct ttaaatacac agtattgtgt
    34261 tttacaaggt actatgttaa aacttcttat atcctcataa taacacagta ctatgttctg
    34321 cacaatagtt atttttaaat attcttgttg attaaatcct tctataaatg tataatactc
    34381 taatcagata tattttatga aagtggtgat aaattggcta aaatgaaaga tgataaaaca
    34441 atattaatcc taactgctca atttggtgct ggacatataa gtgctgcaaa agcagtcaaa
    34501 gaatgtatta ttgaaaaata tagtaactat aatgttgtta tacaaaactt tataaatgca
    34561 agtattccca tgatgaataa gcctatggta aaactttatg aaaacaatac aaaatatact
    34621 cctggattat ataattacta ttattacttt aagaaatcgt ttgattcaag acatgattta
    34681 tctcataaat tatatacacc taaactttct gagtatattg ctgatataaa tccagatttg
    34741 attatctcta catttccact agctgctgct tgtgtaaata actttaagat aaaaaatcct
    34801 gatataaata tacctacact tacagttata acagatgttg tagatagtat ggaatgggtt
    34861 tttgaaaata cagatttgta ttttgttcct tctcctgaaa taaaaaatag attttttcag
    34921 aaaggaataa atccagactc cataaaggtt actggagttc ctgttgataa gagatttcaa
    34981 attgaaagta aagaactatg ttgtgataaa tatagactat tacttctagg tggaggaaga
    35041 ggtctatttg atatagatga ggattttatg cattggatag atgaatttat tgaagaacat
    35101 agtaattcta tagaaattac aatagttact ggtaaaaaca aaaaattata tgacaatcta
    35161 actcataaaa aacctctaaa aaatattaaa gtacttggat ttgtaaacga catgtataat
    35221 ctaataagag aatgtgacct aatgctaact aagcctggag gagcaactat atttgaagct
    35281 attcaatcac aaactccagt actcgtaaaa atgccaaaag ttggacaaga aattgaaaac
    35341 gctaaattta taatagataa gggtcttggc atgatttata gtgatgacct agaccttaaa
    35401 aacatatttt ataaattagt atcaaatgaa tttgattcta taataaactt tatgaaaaaa
    35461 aatttaaaag aatttaaaac agtcattcat ccagagaaaa ttgctgatta tatatcagaa
    35521 ttaatagata atcattacag ttaaattgta ctattaaaaa atttcaaaca taaaattaaa
    35581 ggcaatcaag tatgctttta cacttgagaa tttactcata gtgtttaata atacttgatt
    35641 gcctttatca tatcaaaatc aaattgttat attagtatat atttttcttg tactgcatat
    35701 acagttgttg tatttcttcc atacttctct ttaattctat ttgtaaatct gaagcagtct
    35761 ggtaatcctt attttctata gcttctctca ctctagtgaa tagtgattct ctagttaaag
    35821 tatccttcat aatattgaac tttaaatccg atattgagtt ccaaactacc tcatcaagcg
    35881 catccatatt ttcttttgtg tgtatcttga caatacttct tattttttga atcccagcct
    35941 ctattattct agtttttaat ttcttttgcc acttatctat agctccaatc ttaaatgatt
    36001 ctattatact atcagtaaat acatcacctt gttttaaaga ttttaatttt gaagcatata
    36061 tttctaagtt tttcatattt tcataaactg tagccggtgg tattccaaat cttgcatttc
    36121 tttcttccaa actataatgt tcaaatacat cattttcatc tctatatgct ctatcttttt
    36181 ctaaatagaa actttcttca cctacatttt tagataactc tttttcaagt tcttttgtac
    36241 taagaccact cttagctgct gcttttatac catccaacat tgtttgataa catcctgcta
    36301 ttactaaata cgtgttagat agagggcttg gtgaccttaa ctcaaatctt acagtctttg
    36361 gatttttcat atctcttatt aatccaacaa gcactgacct atttcttgat ggaatctcat
    36421 aactatgacc taaagatgta actatgcata caggagcttc aaatccagga actaatctat
    36481 taaatccatc attagaagct gttacaattg ggtttaatac ttcataattg taaagaagtc
    36541 ccataagagc cccatatcct agttcactta gataatcttc ttttaaatct tttggcgcaa
    36601 atagattttt tatacttcca tcctttaact tcgcacttac tcctacatgt gtatgtccac
    36661 cacttcctgc tactccatga attggttttg ctttaaatgt aacttctagt ccatgtgatg
    36721 taaatacatc ctctataaca tctcttacta ataattcatt gtctgctgct tgtaacggtg
    36781 tagaaaactt ccaagaaacc tctaattgct ccatagcatg gtttgttctt ccatctatac
    36841 taatagaact ttgtattcct ccgacctctt tgtgagccat ttcagggttt acacctagct
    36901 tttgaagtat aattaaactt ttctctaaac aagttcttat aataccatga gttcttttcc
    36961 agtattgctc ttttaggctt tgtgatacat ataatttctc taagtcagct ttatcctcag
    37021 gagtattaac ccagaactca agttctgtag ctgctgttaa cattatttcc tctatatcat
    37081 ctactgaatc tattcctatg ttatttatta catgtggata ttctctaaat atttcataca
    37141 ttgacttttt aaagtactta tctgcttttt gaagtactcc tctagaacat acttttttat
    37201 tatcatgtat taaaaatgca ggtatcttta atgttccaac aggtagacct acttcttcgt
    37261 ctatatattc catattgtaa tctacatacc aatgacaact tttatctggc attaaatcta
    37321 ctttcgcatt atttaatgta gctatattat aaagctcaac acttgaacca tcagtctgta
    37381 tagctgattc caaaaattta tctatatcct ccaaaaataa ttctacagga atcttttcat
    37441 ctgttgcatt tcctcctaaa tcaaccccca ttaaggaaac aaatcttata tttttattgc
    37501 tttttaggat ttctcttaat tcttcattag tgtgtttatc tttctctatt acgtataata
    37561 gactatccat ttttccactc tcccataatt tttatgtata ttttattttg ttaaatacaa
    37621 gataaatttc attttcctta catttatgaa tttttcttgc aaattattcg tgttttattc
    37681 gtgtttttat ttatattatt atatatcaag tataaaaagt tcgcaatatt ttttattgga
    37741 aaaaatatta tacatacaat agtttaacat ttttacaaat atggggtata ctaaaataaa
    37801 agtattttta tttgaaaatt taattttatt tataatataa tctatagtaa aagaaataat
    37861 aaaaaaattt aggagataaa ctttatggaa tacataattt tcgatttgga atttaaccaa
    37921 ggatttgata aaaaactcaa taaaactgta tccaatgaaa agtgtccttt tgaaattata
    37981 caaataggag caattaaatt ggattctaaa ttcaatataa tagatacgtt taatagctat
    38041 gtaaaaccta caatttataa agacatacat ccctttatta gtcgtatgac taatattaaa
    38101 agttctgatt ttaatgattc gcctactttc cctgaggtct acaacaattt tataaaattt
    38161 atatcatcac aagaccctat attatgtgtt tggggagctg gagatttgaa ggaattatac
    38221 aggaatatca actatcacaa gctaccatca aattccttac ctaaatctta tattaatata
    38281 caacaacatg catctaaata tttcaataat ccagcaggaa aaagcattgg cctacaaaat
    38341 gctatttcta tattggaact tgatgaaaaa atgtcttatc acaatgcttt aaatgatgca
    38401 tattatactg ctaaagtttt tattaagata tacaatccaa gtatagtccc agatatatat
    38461 ctttatacga gtataaaacc taaaactata agatattcta acaaaaaaag agttgattat
    38521 gataagttat ttgatgaatt taggaaaatt ttaaatcgtg aattaactaa agacgagaaa
    38581 aaaatcatta acttagctta taatatgtgg aaaacaaatc aatttacatt agaaaatgtt
    38641 aagcaaagaa aaaacaaata gagtttattt agataaaaaa taggcatgta gattaaaaaa
    38701 ctagttaact ttaaatttat atctacagcc caatttttat cataattaat ttttatttta
    38761 tctctaattc aactggacaa tggtctgaac ctaatatttc agtgtgtata tccgcactta
    38821 ctaatctatc ttctaatttt ttggatgcac aaaaataatc tattctccac cctgcattat
    38881 tttttcttgc attaaatcta tacgaccacc aactataaac accttcttta tcaggattaa
    38941 aatatctata tgtgtctata aacccactgt ctaataattt agaaaacttc tctctttctt
    39001 ctttagtaaa acctgcattt ttcatattat ttttaggatt ttttaaatct atttctttat
    39061 gtgcaacgtt catatctcca cacacaatta caggcttatg attatctagt ttggttaaat
    39121 aatctataaa gtcgtcttcc catctagttc tatattctag tctctttaat tcagattgag
    39181 aatttggcgt atatactgta acaaagtaaa aatcttcaaa ctctagagtt atcactctac
    39241 cctctttgtc atgttcttct atatttattc catacattac ttttaaaggc tctttttttg
    39301 taaatatagc agtacctgaa taaccctttc tctcagcata attccaatat tgaaaatatc
    39361 ctggtaaatc taactctatt tgcccttctt gcaatttagt ttcttgtaaa caaaatatat
    39421 ctgcatctac ttctttgaaa aagtctaaaa atcctttccc aacacaagct cttattccat
    39481 taacattcca tgatataaat ttcatactta tactcctcat ctaaacattg acacactccc
    39541 catagctaaa gatgggggct tttcaacaat tttattgtaa attcttaatt tacttttatt
    39601 ttaacaatgc tatactataa tttcatctaa aattactatt tacttaatac ctaaaaatat
    39661 atgttttaat caatttttaa cttttttgtt aaatcttcag ggctcattga agaaacatac
    39721 atatttgttc caagttcaaa tcctccaaaa ttatattttc ttgggattat gtgcatatga
    39781 acattaaaat acgattttgt ttcaatcttt gttggatgag tgtgaataca taaattaaat
    39841 ggcatatatc cattgatatt gtataacttc ttaaacaact tttcaaatat tgtagaaagc
    39901 tcctgtatat tattatcatt taactcacca aactctattt tatctttaaa tattattctt
    39961 acttctccac tatacttggt tgcatatggt ataagtacca aaaaagcttc tccattataa
    40021 acaactcttc tatctaaact tatttcattt tctattaaat catcatacaa agagctttta
    40081 ttgctgtcat aatactcctt tgaaaccaac agttcattcg taatttcagg tggaataaaa
    40141 gacatagaca atatttgagc atgtggatgc atcaaagatg ctcctgcctt tctcaagaag
    40201 tttttgaaga tactaacata ctctacttta tcatctttcg acaaatctct aaatctattt
    40261 ctatacataa aaaaaacatc ttcaaattct ttttgactca tgttataaaa actacgatta
    40321 tgtttatcgc tctctatcat tacttcatga acaccatata catctcttgc catatcatca
    40381 attataggaa atttattgta gacagatttt acaagccatc cttcttcact atctatttca
    40441 aataatgcat cagttgcatg agcttcattt cctttgcaaa atgggcattc ttcatcatat
    40501 tcattagttt cttcatcttc atttgggata tctgctgtat ctaaaggtct ttttaaccta
    40561 tctgtagcaa atataacaac atcattggta attggatcta ttcttaattc tttcataatt
    40621 aacacctctt agttaatagc ctttaatata attatatgat atttatcgta tctgttaaat
    40681 aaatttataa tattttttat aattttgcat atttattatt atatattttg tctatagctg
    40741 aaagattata actaaaaaat cactatcagt acatcagaat attatcttac tataaattaa
    40801 tttatgaata cataatttag tggcataaac atgggtattt tactataatt tgttaaaagt
    40861 ttattttaaa gctatattaa ttttttttga tgatttttac ccataagtat gttattatta
    40921 tcttgtaaag atgtcttgta ttcaaacata caatttacat aatacaatat acgtatttaa
    40981 attaaatagg gggtattaaa atgaattatt caaacagagt tagtgcaatg caagcctctc
    41041 caatcagaaa acttgttcca tttgcacaag cagcaaaaga taaaggaatc aaagtatatc
    41101 acttaaacat aggacaacca gacataaaaa ctcctaaagg attttttgat gctgttaaaa
    41161 actttgatag cgaagtctta gaatatgcta catcagaagg tattccagaa ttattagaag
    41221 cacttcaaaa ttactataaa acttacgata tgaattttga aaaagatgaa ttattagtaa
    41281 ctaacggtgg tagtgaagct ttacttttca ctatgatggc agtttgtgac ccaggagata
    41341 atctattagt tccagaacca ttctatacaa actacaatgg atttggtcaa tctgtaaacg
    41401 tagaagttaa tgctgttaca acaaaggcag aaaacggttt ccaccttcca tctaaagaag
    41461 aaatattgtc taaagtagat gataaaacta aggctataat tctttctaac ccaggaaatc
    41521 caactggtgc aatttataca aaagaagaac ttaatatcct agctgaaata gctaaagaaa
    41581 aagatttatg gataatagca gacgaagttt atagagaatt tgtttatgat gggcttgagt
    41641 atacaagctg tggtaactta gagggtgtac aggatagagt tataataata gacagtgttt
    41701 ctaagagata cagtgcttgt ggtgctagaa ttggttctat cgcttgcaaa aataaaggtc
    41761 ttatcgctca aatacttaaa ttatgtcaag gaagactttg tgttcctaca ttagagcaaa
    41821 taggagctgt tgagttatac aaaactcctg tttcttactt caaagaagtt aatgaagagt
    41881 acaaaaaaag aagagatgta ttatacaatg aattaatgaa ggttgaaggt gttatatgta
    41941 aaaaaccaac tggtgctttc tatatagttg ctaaattacc agttgaaaat gcagaagatt
    42001 tcacaatttg gatgttaaaa gaatttaata aagataatga aacagttatg gtttgccctg
    42061 ctgaaggatt ctatgctact ccaggtttag gacgtgatga aataagatta gcttacatct
    42121 taaatgaaaa agaccttcat agagctgcta cattattaaa agaaggttta gagcaatatg
    42181 tagctttaca aaaataattt tttaaactta atttatataa atttaatgat ataaaatgtc
    42241 cccttttcag atattatttg aaaaggggac atttcttaat taatatatta attaagactt
    42301 agacctgact atttttcatt ttctttatat agtgttggcc agtaatcttt attcacttta
    42361 attaaagcat ctaaaacttg tcttgcctta gttagagaaa ttataaaaaa gtacatcaag
    42421 aaaatttaag atgtactttt tagattgtat ttagacttat aattatatag ttaaataaat
    42481 aacaaagaat taatcttagt accattaaat acaaaaattt ttatattttt tctatctaaa
    42541 ttcttctttg tttaatatat attgaagagt atttattgct tctaaatatt tttttctgtc
    42601 ttcttcagtt aatttagaaa gtttttctcc taaaccatca cttaatttat ccataaaatc
    42661 agttgctatc ttatctccct cttcagtaat gtcaattaga tattttcttc tatcaactaa
    42721 atctcttttc cttgttacat acttcttatc agttaaatca tcaaccatac tagttaaact
    42781 gcctttttct atatttaact tagagcataa atcagtcata cttattactc cataattttt
    42841 tatgaaaact aatgctctta attgtgtttt atttacatta taatctggtg caaatttttt
    42901 taggtcttct aagtacaggc tagaataaat cttaggaaat gtttttacta aaaaacttat
    42961 ggtatctttt actatatagt tcatataatc acctcggttg ttttaaaatt tattaaatta
    43021 tctaaataac tttatttcag tttacattaa aaatattgca agtacaatag tttttgctga
    43081 atgtttaaat ttaattagta atcttatcat ttttttattt ttatttatat tattcctatt
    43141 aaatattatt tatatagcta ttttattaaa ttcatggtat agtaagtaaa gaagaactct
    43201 tcacagcggt ggagagaaga cgctagccca ttaaaatggc tatcttattt ataaataaga
    43261 tagccgtttt taattatatt ttatctgtac aattctatac tcttaggtct acatctactt
    43321 ttcctaagtc ttccttataa tcttttatag caggttctac aacttcattt acaaattcta
    43381 caacttgttc tggagctcta cctataaagt tttttgggtc cattatagat agtatttctt
    43441 ccttgctcat tttaaatgaa tcatcattca ttataagttc aattaagtta ttatccttgc
    43501 cttcatgctt tactctatag gcagctttca tagaatattc tcttattatt tcatgcaatt
    43561 cctgtctatc tccacctctt tttacagctt ccataagtat tgtttctgta gccataaaag
    43621 gaagttcttc atttacacgt ctatttatca tattttcata tactactaaa ccatcagtta
    43681 catttatccc tatttcaagt atagcatctg ctgccataaa tgcttgaggt attgccaatc
    43741 tcttattggc tgagtcatct aatgttctct ctaaccattg agtggcttgt accattgcag
    43801 ggcttataga ttcagagatt atatacttag ataaagatgc tattctctca cttctcattg
    43861 gattcctctt ataagccatt gctgatgaac ctatttgatt tttttcaaat ggctcttcta
    43921 attcttttaa actttgtaaa agtcttatat cattagtcat cttatgcata ctttgagcta
    43981 tccctgatag tatgcttatt acttgataat ctaactttct agtatatgtc tgtccactta
    44041 ctgcatagga agaatggtat cccatctttt tacaaatttt cttatctaac tcttttactt
    44101 tttcgtggtc tccttcaaat aagcttaaaa aacttgcttg agtaccagta gtacctttaa
    44161 ctcctcttaa cttcatgttg tctattctat agtttaaatc ttccaaatca agaattaaat
    44221 cttgagccca taaacaagct ctttttccta ctgttgtaag ttgagcagct tggaagtgtg
    44281 taaatccaag agctggcata tctttgtact taagtgcaaa ttcttttaaa ttgtttatta
    44341 aatttacaag ctttactctt agaagtttta aagcttcatt catttgtata acatctgtat
    44401 tatctccaac atatgcagat gttgctccta aatgtattat tcctttggct ttttcacatt
    44461 gtaaaccata agcttttacg tgagacatta catcatgtct tacttctttt tctatttttc
    44521 tagcttcatc aaaatttata ttatctatat tagctcttag ctcatctaat tgttcttcag
    44581 ttatattgat tcctaactca tgttcacctt ctgcaagtgc aacccataac cttctccatg
    44641 tagagaattt aaattgtgga gaaaatatat aactcatgtc cttgctacaa tatctgtctg
    44701 taagtgggtt tgagtaagta gtatatttat tatctatcat tatattagca ccttccttaa
    44761 atcttttgtc gtgtgattac tgtgtacaca ttagtacata aataattata tataatttta
    44821 cgaactataa caagactttt ttattttttg ttcacattta tatatagtat tttttattta
    44881 ttactatttt ttatttatat ccaaattatc tttttcaatt aagtaatcca ctatttcact
    44941 atcaacaaaa tttaatacat acttatatct aattgcatag tatttatcac tccatccaag
    45001 ctgatttttt acatcacttt catctgcccc aagccttaaa cttattgctg caaatgaatg
    45061 tctaaaatct cttgctgaat attgagaaag tccagctaaa tctaatgctt ttttgactat
    45121 aagtctgaca tttctatctg ttatagaatt actcttttga gttgtaaaaa taaaatcatc
    45181 actaggtatt attacctctg gaagcccaga ataattcctg taatcttcta aaagtttaaa
    45241 aaagtatgga tgtaatttaa ctactctttc ttttcttccc ttacctaacc ttacatatga
    45301 gttatcgttt tcatctacca taaggtcttt ccactttaag ctaactaatt catttaataa
    45361 acacccagta gtaactagac agactattat tactctatct cttatattta attttggtag
    45421 gatacctata agtttattta tttcttgtat acttagaaca tcatcttttg tttttattct
    45481 tgttactgtg ggtttttcta catatctaaa tggatttata tctatgtatc cttctttttt
    45541 taagaagtta taaaaactat gtaaataact atatatcttt tcacaagttg atttcgcata
    45601 tttagtctgt atatagtcta caaaattttt acaatcttct ttcgtagcat aaatcaattc
    45661 tttccctttt aaaaattctt taaacagtat aacctttgat aaataatcgt gtttcgtgtt
    45721 tggatttaat tttgtagaaa aaacattaaa agtttcatac tcataatcat ctagtatttt
    45781 tgtactatac ataataactc ctttcctttt cataaaataa aatagctata cttttactat
    45841 accatatatt tccccctcaa atatacccct tattcaatag ataactttta agtttatttt
    45901 gttatattat gaaggtttta tgaaaatatc aatcttccat tgtgcactac acagtactat
    45961 ggtattataa gttagtaaaa ggtggcattt ttttattaat ctatgaataa aatatgctac
    46021 tataaatttg tattggaggt attttgattt ggaaacattt agtttgcttg aaatttttaa
    46081 ggcagtcatt ttgggcatag ttcagggaat aacagaatgg ctaccagtaa gtagtacagg
    46141 gcatatgata ttagttgatg agtttataaa attgaatttt tcaaatacat ttataagtac
    46201 atttttagtt gtaattcaat ttggttcaat attagctgta cttgttatat tttttagaaa
    46261 attaaatcct tttgatagcg caaagaatat taagcagaaa aaagaaacag tccgtttatg
    46321 gcttaaggtt ataattgcag ttataccatc tggagttatt ggaatactgt ttgaagatga
    46381 tatagataga ttattcttta attcaacagt agttgctatt gctcttattg tatatggtat
    46441 aataatgata gggcttgaaa agagaaataa aaaacctaag tataaagatt tttctcaagt
    46501 tacatataaa ttagctcttt gtataggatt attccagtgt ctagctctta taccaggtac
    46561 atctaggtct ggttctacta taataggtgc agtattactt ggtacttcta gatatgtagc
    46621 agcagagttt tcattcttct tagccatccc tacaatgctt ggagctagtg cattaaaact
    46681 tctaaaagct ggatttggat ttactggatt tgaatggctt attttaggtg ttggttctgt
    46741 agtagcattt gttgtttcaa ttgtagttat taaatttttt atggactata tcaaaaaaca
    46801 tgacttcaaa gtatttggtt attatagaat agtcttgggt atagtggttc ttgcttattt
    46861 ctttctatta taatgtattc taatttaata acaaatgata aggagaaaag ttatgagtgt
    46921 taaaaaagaa atatttgatt ggattaagtc aatagctatg gctattgtac ttgcatttgt
    46981 aattctacaa tttataagac cttctattgt aagtggagaa tcaatgtatc ctactttaga
    47041 tgataaagat tatctgattt taaataggat atcatacaag gttggtaaac ctgaaaaagg
    47101 cgatattgta gtttttaaaa ccaatttagt tgatggagaa acaggaaaga aaaaagactt
    47161 aataaaaaga gttatagcta ctgaaggtga cagaataaaa atatcaaatt ctaaagtgta
    47221 tgtaaatgga aaattattaa atgaaccata tatacacaat aactatactt ctggagatat
    47281 agatactgtt gttccaaaag gtaaactatt tgcaatggga gataatagag aaaatagtaa
    47341 tgatagtaga ttccctgatg taggtatggt tgatgaagat gaagttcttg gtaaggttat
    47401 ggtgagacta ttacctcttg ataatattgg gaaagtagac taaaaaataa gagactgaat
    47461 tggtaaagtt tattttacaa atctcagtct ctttttattt tcttaaatta caaatatttt
    47521 tttactaaat atcttttgat tctgtaataa gtcttattat atcacttgct tcttcattaa
    47581 aagttgttac tatacttagg tagtctgttg ctctactcat agctaaataa accttattta
    47641 aatctcctac aaagtcattt acttgataat cttgttcaat atcatttata gtttgattgt
    47701 ataacatctc taattcacat actattaccg ctttatactc taaattcttt attgcatata
    47761 tatttgctat tgtagttcct accttcttac ttatatttgt caaattatct tctgcacata
    47821 tataaggaat ttttgcctct tccaatgctt tttttaacat atattgaaag taaatggttt
    47881 ttccactttt taatttcttc ttattgtaag gataaacgat agcaacttca gaataatcaa
    47941 gacctttttt acttattaaa tactcaattt cccagattac agaacttatt tggtcatcaa
    48001 ggtcacttac ttttattata tcaacagact tatttccacc tctaagtgct ttagtataaa
    48061 agaaagtact aaattctgta tttggtctta attcgttgat atatgagtta gaattatttg
    48121 aaaatttatt tgtaaaatct acaatctctt tagcttgtct ataattttta cttaagataa
    48181 tcttatcatc aaattctata ccattatata attttttaaa tatattcaat ctattagaga
    48241 tattcaagga gttacaagaa cacacattaa atatgaattt tgttttatat aaaaactccc
    48301 ttataaaatc tatttcatac tctaaaaagc tttctgcttc atcaataaaa atagccttga
    48361 acatattttt attttttata atgttctgtg cttgttttac aagattatta aaggtctttt
    48421 cgtaatcatt ttttaacatg ttataatcta caattaaatt gaatttttta gctagtttaa
    48481 atataaaaga actaaatgtg tgaacttcta aattgttatt atctttgtat aataactcta
    48541 tcctctctcg aagctcattg cacagttgtt ttgtatgtgt aaatatgact aatttatgat
    48601 gtggatatac ttttgctaat tttatagccc tagaaagcat aattgctgtt ttgcctatac
    48661 cagaaccacc ttcaataagt gtattcccat atttaataga aacaacatct ttaatttgaa
    48721 cgtcttccat catagttgct gtatacttat agtcatcatt gtagaatgaa atttttttaa
    48781 atttttcatt tagatgaagt ttatcattta ttatatagta ttctgaacat atgtctagta
    48841 aaaataaatt taagtttatt tcatcattct catcattaag atattcctcc agcgaaccct
    48901 tattcattat atcttgaagc ttatttttat ctattatatt attattaaca aattcttcaa
    48961 attcatatgt ttcctcaact tcaacgtatg gcataatgta aacgtagtta taacttatat
    49021 ttctattctt ttgtcccatt tttagtttca aaagttcata ttcctcattc ataacttcaa
    49081 gtaactcttc ttctaaaata aaaaatatat cttctgttgt atccataaat tttataaata
    49141 aaattcttcc atctttaaca tacaacaaat cggtatttat tcctttaaaa ggagtaactt
    49201 ttggcactac tttaacgtcc tcattgatat tttcgtaaaa tattttctcg aactccttca
    49261 attttagggc gtctaactga gaatttatat ttatgtattg gctcacttac attacctcct
    49321 tctgttatac ttaattatac cattttgaac tatattttta tatatacttt ttataggcaa
    49381 atttagtaaa taaattcaaa ataaatacaa ataaatacaa aactgctaaa aaaattttgc
//
LOCUS       DAMKNB010000022        48588 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.023, whole genome shotgun sequence.
ACCESSION   DAMKNB010000022 DAMKNB010000000
VERSION     DAMKNB010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 48588)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 48588)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..48588
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.023"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            59..793
                     /locus_tag="PC494_001435"
     CDS             59..793
                     /locus_tag="PC494_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HDF3911940.1"
                     /translation="MKQNKYDDDRFFNKYSKMERSTNGLAGAGEWHVLKKMLPDFKGK
                     RVLDLGCGFGWHCQYAVENGAISAVGVDISEKMLKEARNKTQLDNINYICMPIEDINF
                     PKDSFDVVISSLAFHYIQSFEDICKNISNCLSNKGNFAFSVEHPIFTAYGSQEWYCDK
                     DGNNLHWPVDRYFEEGVRRSNFLGEEVIKYHKTLTTYLNTLMKTGFEILEIIEPQPEE
                     KLLDTIPDMKDELRRPMMLLVSAKKR"
     gene            complement(936..1427)
                     /locus_tag="PC494_001436"
     CDS             complement(936..1427)
                     /locus_tag="PC494_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA synthetase associated
                     domain-containing protein"
                     /protein_id="HDF3911941.1"
                     /translation="MNNQQQEVYKKLDELSIPYEAVNHPPVYTIEEMEELKTLHMEFV
                     VKNLFLRDAKGKEHFLVVLGKDKKADLKDIRQQIDSKPLSFASEERLQKYLKLTKGAV
                     TPFGILNDKEAVVKVVFDKDLLKMDKIGIHPNDNTATVFLKFEDMKKLIEENGNEIYY
                     VEV"
     gene            1776..2159
                     /locus_tag="PC494_001437"
     CDS             1776..2159
                     /locus_tag="PC494_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3911942.1"
                     /translation="MSTDKVVGIIDEETAELAGIEYTGKIYASSGVIKHIKKKHRCQL
                     SKDIFNDIIDTIKMVLKSPEYIGSHPKKPGKSVEFIKKIDDYILVATELDTKKGYLYV
                     SSMYAIKEAKLESRVNSGRVKQYDG"
     gene            2665..3048
                     /locus_tag="PC494_001438"
     CDS             2665..3048
                     /locus_tag="PC494_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HDF3911943.1"
                     /translation="MNLTKKIEDKRKAKQRAEKVKKAKIATAGVVLGAVTGAVSGVLL
                     APKSGKETREDIKDASQQIAEKINMKTVDVKGKVSEKLEDKKGNFIESKKKIKKYIDN
                     KKSVENSSEEDKIIDIVEPVSVTEE"
     gene            3050..3400
                     /locus_tag="PC494_001439"
     CDS             3050..3400
                     /locus_tag="PC494_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3911944.1"
                     /translation="MDNTITINISIIYVLLAILACIALVYLIIVLVKLHKILNNVGTM
                     LNENTQNINTTLNNLPNVVETFGEVGENMKDVTEVVTEVTADFLVTKDSVKSNMDVIV
                     DILTIIKNIFLDKK"
     gene            complement(3501..3959)
                     /locus_tag="PC494_001440"
     CDS             complement(3501..3959)
                     /locus_tag="PC494_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3911945.1"
                     /translation="MIRTKVVELIATVCRENKPHKWVDENYTPYDKSGKVELMSIEDL
                     NELISSSGRADFLYSSRLQKLLNEVYINQSRASYISGCGLFWSSYWDILEEKFEEWLY
                     NSYIFFDEDDEYLEGMEDFELECKDVLMDVIETTSIDIYVQMIKRNITNY"
     gene            complement(4004..4792)
                     /locus_tag="PC494_001441"
     CDS             complement(4004..4792)
                     /locus_tag="PC494_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HDF3911946.1"
                     /translation="MKVVIIPGHTLIGKGTGAVGYINESKETRILNDLIVKWLKIGGA
                     TVYTGRVDESSNHLADQCAIANKQETDLAVQIHFNSNATTSTPVGTETIYKTNNGKTY
                     AERVNTRLATVFKDRGAKSDVRGLYWLNHTIAPAILIEVCFVDSKADTDYYVNNKDKV
                     AKLIAEGILNKSISNSQGGGENKVYENVIVYTGDADKVAAQILHWQLKDSLIIEASSY
                     KQGLGKKVYVVGGEANKLVKGDVVINGADRYETVKLALQEIDKL"
     gene            complement(4931..5368)
                     /locus_tag="PC494_001442"
     CDS             complement(4931..5368)
                     /locus_tag="PC494_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine/deoxycytidylate deaminase family
                     protein"
                     /protein_id="HDF3911947.1"
                     /translation="MNKKLENRCSWQEYFMRLCETVAERGTCDRAYVGAIIVNSENRI
                     VSTGYNGSISGDKHCSEVGHEMRDGHCIRTIHAEQNALYYCAKEGISVKNCSIYVTHF
                     PCLNCTKAIIQAGIKHIYYRTGYRIDEYAIKLLQSSNVLYTKL"
     gene            6190..6699
                     /locus_tag="PC494_001443"
     CDS             6190..6699
                     /locus_tag="PC494_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF3911948.1"
                     /translation="MLSENIKTIRKSKGLSQQELAIKLNVVRQTISKWEQGLSVPDSD
                     MLISISEVLETPVSTLLGETIVESEVDSLKVISEKLEIINLQLAQRKNMRRKMFHWLF
                     ILLCAVILIGFVVLGGLNSPYLDWNYTDPETAVFGVAFHAFEWLFVRLVPIVLIGAII
                     GIFVTRKKI"
     gene            7104..7640
                     /locus_tag="PC494_001444"
     CDS             7104..7640
                     /locus_tag="PC494_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HDF3911949.1"
                     /translation="MQGGVNIRQVKSFVFPVISLIFLDQISKVLIGLFLMDFEIDIIG
                     KFLRFNPVQNTNLSYGGNFIGILSNLWVLVLFNILVILVIISGYAFYKSKNEQTSYSV
                     KVIMSCGLAGTICSLIDKLFWGGSLDFLQIPSFFIFDLKDCYLTVAEIIFVVIGILHN
                     REISMKEYIYFCYRQFKK"
     gene            complement(8074..8874)
                     /locus_tag="PC494_001445"
     CDS             complement(8074..8874)
                     /locus_tag="PC494_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF3911950.1"
                     /translation="MRLNKRSEGYINYVKGVKREKRNVLFYQLLILIGFIVIWELLAD
                     LNVINTFLFSKPSDIYNLFIQYAFSGQLFKHIGISVYETVLGLVIGTVLGILVAIALW
                     WSEKLSKILDPFLVVLNALPKTALAPIIIVWVGAGIEGIVVTAVTISVVVTILSAYNY
                     FMNIDEEKIKMLKSFGATKSQILFKLILPANTGNLINLTKINIGMAWVGVIVGEFLVS
                     RYGIGYLIVYGSQVFKLDLVMMGVFVLAICAWAMYAVVNIIEKIYNSR"
     gene            complement(9069..10667)
                     /locus_tag="PC494_001446"
     CDS             complement(9069..10667)
                     /locus_tag="PC494_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HDF3911951.1"
                     /translation="MKAAIYSRKSRFTGKGDSIENQIQLCIDYAKSIGVKDFLIYEDE
                     GFSGSNIDRPQFKKMMQDAKDKKFSYLVCYRLDRISRNVSDFSTLIEKLNELNISFIS
                     IKEQFDTSTPMGRAMMFISSVFAQLERETIAERIKDNMYELARSGRWLGGNTPHGFNS
                     EKITFLDENLKERSMYKLQVNDEQMEIVKLIYNKYLELRSLSKLYKYVYNNGIRGPRG
                     GKFDPSSLSRILRNPAYVKANDEILDYLKNSGMDVVGTPDRKCGILTYAKNTSNSIAA
                     IAKHHGVIEPEIWLEVQNQLDKNRDKTPRISTGKTALLSGLIKCGKCGSNMRITYKGK
                     KTDKDLKYYYICGTKKTLGSDSCNCKNLNGPLVESLVIDKIKNCKEESIISAFNSNNI
                     KTDNVFNIFKSETNLLKNQILDKERLIKNLVIELAKNTGSTASDYIVSQIESLNNEIS
                     ILKDKINILESSNINISSDSINIDIIVSNLKRFNDEVDNASLDDKRLLLSTIINSIVW
                     DSSLGNLNIVYMGAEVDNSVSLSN"
     gene            10995..11171
                     /locus_tag="PC494_001447"
     CDS             10995..11171
                     /locus_tag="PC494_001447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3911952.1"
                     /translation="MEINVIEIFPKDKAKLNKIEMDKASWFVNIISKKYPKEALNEAF
                     STLEKELNISKANT"
     gene            11345..12475
                     /locus_tag="PC494_001448"
     CDS             11345..12475
                     /locus_tag="PC494_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003462216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HDF3911953.1"
                     /translation="MNNFEIKTRIKFGEGSLKALQELKNKNVLIITDPFMVKSKTIDK
                     ITSNLINSTYQVFEEIVPDPPIEVVVAGIEAFKSINPDVIIALGGGSAIDAAKSIMDF
                     SKKILKINEVEFIAIPTTSGTGSEVTSFAVITDSQKKCKYPLVSDDLLPDMAILDPEL
                     VKTVPNFITADTGMDVLTHAIEAYVSTNSNDFSDALAEKAIKLVFKYLIKSYKDGNDI
                     EAREKMHNASCLAGMAFNQASLGINHSIAHVLGGKFHIPHGRTNSILLPHVIEYNSSI
                     VGYTNTTYSDTAKKYAQIAELVGLGSANIRISVRNLVNEIKKLQKEMNMPTKLTQCKL
                     SLEDITNEEREIAKLAIKDTCTLTNPKVPTEDDIINILKNIK"
     gene            12716..13066
                     /locus_tag="PC494_001449"
     CDS             12716..13066
                     /locus_tag="PC494_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003453843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMC domain-containing protein"
                     /protein_id="HDF3911954.1"
                     /translation="MTEESKQRVIQEYVPGKQVTLAHIIANPNEDIYKKLGLVLDKKD
                     AIGILTITPSEASIIAADVATKASNVSLGFIDRFSGSVVISGDVSSVESALNDVLEVL
                     GNMLNFSSTKITRT"
     gene            13074..13523
                     /locus_tag="PC494_001450"
     CDS             13074..13523
                     /locus_tag="PC494_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EutP/PduV family microcompartment system
                     protein"
                     /protein_id="HDF3911955.1"
                     /translation="MKNIIFMGKTGSGKTTLCQKLDQLELKYKKTQSVELYNNAIDTP
                     GEYMENRNLYNALITTSADAKIIAIVYDATQEENYIAPGFASMFCKDVIGIITKINKA
                     TENEVNIAYERLSLAGASQIFKIDTVDNIGLEKLFKYLEKYKNIDEV"
     gene            13625..14200
                     /locus_tag="PC494_001451"
     CDS             13625..14200
                     /locus_tag="PC494_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HDF3911956.1"
                     /translation="MGKKILLVDDEPLLRMDTKDILESHGYEIIGEASDGFEAVEMCK
                     KHKPDLVIMDIEMPILDGIKAGKIICKENLAGGVLLLTSFEDKEYVEKAKSIGAYGYL
                     VKTASEKSLIPTIEMCLNKVNEFEKMKKDLEKVNSKLNERKLVERAKGILIREFKISE
                     DEAYTRIRKLSMDKRTTMMEIAKMIIIGYDD"
     gene            14193..15602
                     /locus_tag="PC494_001452"
     CDS             14193..15602
                     /locus_tag="PC494_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase N-terminal domain-containing
                     protein"
                     /protein_id="HDF3911957.1"
                     /translation="MTNTIKKISTAQTYLNNNEIEKIIEVSKSLDLMASFYEADVFID
                     VLSKFDDEAIVVAHGRPKEKSMYCENVIGKKALIENEPGVIKCLKTGERVRDIKALTQ
                     EYKLVKQNIQPITLDDKVLAVLIVEKDISSEVKNEFNASEDEENKNLHQFIKLIGNND
                     FLVDNLNSAILIFDKNGKLKIKNRIATEIYKNLGFGYDIQDMHYNDLDIETNTFENIL
                     MDENYDETNEVSIGNMFFKIKTIYIKDDEFKVCKIVQDISDLKRKEEELVLKTVAIRE
                     AHHRVKNNLHTVISIIKKQSRLSQNDEVKQCLDNIINRVFAILSTHYLLSKEVDNNIS
                     IREGINLLVSNIQGGYLFSKDIDIRITGEDFKISGEKATAILLVINEILQNCYDHAFS
                     DREHGTIQILINKDNDYRNIAIIDDGIGFDSNNINKNSLGTYIIDSYITQMLKGNIER
                     KSSENGTEVLITIPTQINI"
     gene            15786..17219
                     /gene="eutA"
                     /locus_tag="PC494_001453"
     CDS             15786..17219
                     /gene="eutA"
                     /locus_tag="PC494_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004458698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine ammonia-lyase reactivating factor
                     EutA"
                     /protein_id="HDF3911958.1"
                     /translation="MREELLSVGIDIGTSTTQLIFSKLIVENTESNFSVPRISIVDKE
                     IIYKSKVYFTPLISNNEINGQQIKDIVENEYKKANISKEDIHTGAVIITGETARKENA
                     NDVLHTLSGFAGDFVVATAGPDLESIISGKGAGAHIYSKEHSTTIVNIDIGGGTSNIA
                     SFKRGEVTDTGCLDIGGRLVKIDKISKKITYISPKIDKIIKDNNLNLQVGTMATVENT
                     KPIVDIMVDLLMESIGLKKQTPLFDFIITNKSISIDETIKNVSFSGGVADYIYYDGEI
                     KDYFEYGDLGILLGQAIKNCEYLKKVNVVKSMETIRATVVGAGSHTTEVSGSTITYTS
                     EKFPLKNLPVLKLSIDEETGTSKQISEAIKNKLNWFKLENDLQKVAIAMIGKKNPTFL
                     DIQEYAKGFVDGMQQIIENDLPFIVIVENDMAKVLGQAIYALLNYEKEIVCIDSVKVE
                     NGDYIDIGKPIVEGKVLPVVIKTLVFN"
     gene            17237..18601
                     /locus_tag="PC494_001454"
     CDS             17237..18601
                     /locus_tag="PC494_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003454054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine ammonia-lyase subunit EutB"
                     /protein_id="HDF3911959.1"
                     /translation="MILNTKLFGRTYQFKGLYDVMAKANEEKSGDKLAGLAAESAEER
                     IAAKVVLSHIKLEDIRNNPAVAYEEDEVTRIIQDAVNEKVYEEIKNWTVSELREWLLD
                     SNTTSLDIRRISRGLTSEMIAAVAKLMSNMDLVYAAKKIKVTAHCNTTIGEQGTLSAR
                     LQPNHPTDDPDGILASLLEGLTFGIGDAVLGLNPVDDSVESVTKVLKRFEEVKQKYQI
                     PTQTCVLAHVTTQMEAIRNGAPADLIFQSIAGSEKGNEAFGFNGDTIEEARQLALKHG
                     TATGPNVMYFETGQGSELSSEAHHGIDQVTMEARCYGFAKKYEPFLVNTVVGFIGPEY
                     LYDAREVVRAGLEDHFMGKLHGLPMGVDVCYTNHMKADQNDMENLAILLTTAGCTYFM
                     GIPHGDDVMLNYQTTGYHETASLREMFGLTAIKEFDAWMEKMGFSKDGKLTELAGDAS
                     VLLG"
     gene            18614..19495
                     /gene="eutC"
                     /locus_tag="PC494_001455"
     CDS             18614..19495
                     /gene="eutC"
                     /locus_tag="PC494_001455"
                     /EC_number="4.3.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014952556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine ammonia-lyase subunit EutC"
                     /protein_id="HDF3911960.1"
                     /translation="MNEKDLKALVEQLVGQMVGELDTNVVSETVKKATEVVVDNNAYI
                     DDITEVDIRKQLLVKNPKDAEAYLDMKAKTPARLGIGRAGTRYKTETVLRFRADHAAA
                     QDAVFSYVDEEFIKGNNMFAVETLCKDKDEYLTRPDLGRKFSPETINNIKSKFGTNQK
                     VLILVGDGLSSAAIEANLKDCVPAIKQGLKMYGIDSSEILFVKHCRVGAMDHLGEELG
                     CEVICMLVGERPGLVTAESMSAYIAYKPYIGMAEAKRTVISNIHKGGTTAVEAGAHIA
                     ELIKTMLDKKASGIDLK"
     gene            19515..20168
                     /gene="eutL"
                     /locus_tag="PC494_001456"
     CDS             19515..20168
                     /gene="eutL"
                     /locus_tag="PC494_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003761789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization microcompartment
                     protein EutL"
                     /protein_id="HDF3911961.1"
                     /translation="MKNDVIRPNILGIKIISNISPEMAQKLELKSHHKSLGLITADCD
                     DVTYTALDEATKASEVDVVYAKSMYAGAANASTKLAGEVLGIIAGPSPAEVRSGLNAV
                     VDFLEYGATFISANDDDSIAYYAHCVSRTGTYLSEVAGIREGEALAYLVAPPLEAMYA
                     LDAAMKAADVKMCELFAPPTETNFGGALLTGSQSACKAACDAFAEAVKSVADNPTGF"
     gene            20179..20880
                     /locus_tag="PC494_001457"
     CDS             20179..20880
                     /locus_tag="PC494_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMC domain-containing protein"
                     /protein_id="HDF3911962.1"
                     /translation="MDAIGLIEVIGYVAAIEASDACLKSANVNIVRVDKVGAGIVTLT
                     ICGDVGAVKAALEAGEIAASRVGTLRTSHIIPRIHNEVTNALFKTKEPKVCEVSEDKE
                     KNFEITLEITDNVSKNLSEKENVILDVNENSGNTENLYSDIDKTNKKIETVDDSLTEA
                     NEEKIENTNDKEVLEQVKIENSDFDRDDLSKNSVKKLKAMAKKLDSSITYKDLNVLKK
                     EELINLVKKLSRRDR"
     gene            20883..22352
                     /locus_tag="PC494_001458"
     CDS             20883..22352
                     /locus_tag="PC494_001458"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetaldehyde dehydrogenase (acetylating)"
                     /protein_id="HDF3911963.1"
                     /translation="MTLLDKDLVSIQEVRTLVRRSKVAQEKLSKMSQEQIDKIVKSVV
                     DAAFNNATKLAKMANEETGFGKWEDKVIKNTFASMGVYETLKNTKTIGIIGEDKEANT
                     IDIATPVGVVAGLIPSTNPTSTVIYKTIISLKAGNTIVFSPHPNAKNCILETVNIISE
                     AAIKAGAPEDSILCITNPSIVGTNELMKHKDTNLILATGGEAMVRAAYSSGTPAIGVG
                     PGNGPAFIDKSANVKLAIKRIIDSKTFDNGVICASEQSIVIEKSMEETVLKELKNQGA
                     YVLNEEESERLAKFILRANGTMNPQIVGKSVEVIANLADLTNVPKNTKVLVARENKVG
                     HNVAYSREKLTPILAFYVEENVEAIMNRCREILLNEGAGHTFSMHVNDEELVKRFALN
                     MPVSRILVNTPSALGGIGASTNLVPALTLGCGAIGGSSTSNNIGPLDLINVKRVAYGI
                     KEIEELGRDKSQVEKSMFDSMDKEELINLLVQKLVKELA"
     gene            22448..22735
                     /gene="eutM"
                     /locus_tag="PC494_001459"
     CDS             22448..22735
                     /gene="eutM"
                     /locus_tag="PC494_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization microcompartment
                     protein EutM"
                     /protein_id="HDF3911964.1"
                     /translation="MASANALGMIETKGLVGAIEAADAMVKAANVQLVGKEQVGGGLV
                     TVMVRGDVGAVKAATDAGAAAAERVGELISVHVIPRPHFEVDAILPKVSAE"
     gene            22862..23623
                     /locus_tag="PC494_001460"
     CDS             22862..23623
                     /locus_tag="PC494_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP--cob(I)alamin adenosyltransferase"
                     /protein_id="HDF3911965.1"
                     /translation="MGVLTESEVKRKIGKNKNNITEFYIEKGQIITPSAKSYLAERSI
                     ELKYVDKLSDVNNEPKEVVKEVVKEKKYRYTTVFGAKLDEKPEHMTQLNGNLLVFKDH
                     KRIILRGKIDSLESEILKVQILCQKLDMPKLVKELQEVLDFVRNIMRCEVLDEKLGDF
                     KLLGLTPQELREQSHYPKKYFGIGHEFPSYEMGEVVVAINSIRSNTREVELAAYEAFK
                     GEYGNVHREDLIKALNRLSSVFWIMIYKVRTNKYK"
     gene            23636..24265
                     /locus_tag="PC494_001461"
     CDS             23636..24265
                     /locus_tag="PC494_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate propanoyltransferase"
                     /protein_id="HDF3911966.1"
                     /translation="MENLLNEIVEEVITRVKKEAFIEVEASGRHVHLSREDVDKLFGE
                     GYTLTKLKDLSQPGQYACKERVTITGPKGSIKNVVVLGPCRNETQVEISLTDGSTLGL
                     KAPIKQSGDLEGTLSIKISTQYGEVELDKGLMVAKRHIHMTPKDAEKFNVCDKEIVEA
                     KVMGQRPLTFDDVVIRVSDSFKTYMHIDYDEANACGYSKGTVAKIIKKA"
     gene            24307..25032
                     /locus_tag="PC494_001462"
     CDS             24307..25032
                     /locus_tag="PC494_001462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR02536 family ethanolamine utilization
                     protein"
                     /protein_id="HDF3911967.1"
                     /translation="MNYDNLVDLITEEIYKKINSNEIKISNKPKAVIVFEQDNNKFNL
                     LKDEFEIVEFDKSIRECEIVIVSRLCMRGLSNIALGNSTSDEERFILKMIMKGKEVYV
                     LDEGIEYKKYKDTAPKALYKKFMSFEDEICKFGVEIIKDLNVITKNKLNIKKELESTR
                     GSKKEDTKVLDKDVLNLISVESVKIDNEFSLDLRNKKLISEADLRKPTINGVKNILVN
                     KKSIITPLAVDFMRIHHLKLKKV"
     gene            25045..25317
                     /locus_tag="PC494_001463"
     CDS             25045..25317
                     /locus_tag="PC494_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EutN/CcmL family microcompartment protein"
                     /protein_id="HDF3911968.1"
                     /translation="MDIGKVVGNVWATRKDEKLCGQKLLVVKILKTKDTYKEGFMVAA
                     DNAGAGNGDLVLISKGSSARESIEKSHVPVDATIVGVVDSFEVFDE"
     gene            25310..25861
                     /locus_tag="PC494_001464"
     CDS             25310..25861
                     /locus_tag="PC494_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMC domain-containing protein"
                     /protein_id="HDF3911969.1"
                     /translation="MNKSIGAIEFKSIAKGIEVSNEMIKKSSVDVLYLKSICPGKFLI
                     IVGGETSYINECVDYGIKLGEGYIVDNFVINAISQEILDGFKNKYQKLDSIVSIGVVE
                     SSKVCAGIKMLDKTLKSGDLVLVKLQLSFAIGGKLVYIVAGDLSSLEYALKESENVVR
                     EKEVIYKTVIPSVDSQIIKSLIK"
     gene            25873..26964
                     /gene="eutH"
                     /locus_tag="PC494_001465"
     CDS             25873..26964
                     /gene="eutH"
                     /locus_tag="PC494_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization protein EutH"
                     /protein_id="HDF3911970.1"
                     /translation="MSINEIIIYVMVVFMVLGAIDKCIGNKFGLGEQFEEGIMAMGSL
                     AVAMVGVICLAPVLADVLRPIVVPVFNILGADPAMFAGSLLANDMGGAPLALELAKDP
                     NAGLFGGLIVGAMMGPTIVFIIPVALGIIEKEDQKFLATGILAGIITIPIGAFVGGLV
                     AGFEVMMVLRNLVPIIIFAVVIALGLLKFENAMIKGFTYFGKGVVIVITLGLAAAIVE
                     ALTGIVVIPGMKPISEGIEIVGDIAIVLAGAFPLVFVITKVFNKPLMALGKVLGMNDV
                     SAAGLVASLANCIPMFGMMKDMDNRGKIINVAFSVSAAFVFGDHLGFTAGFNSNMITP
                     MIVAKLVGGITAVLLAMVIANKTLKKENV"
     gene            26966..27439
                     /locus_tag="PC494_001466"
     CDS             26966..27439
                     /locus_tag="PC494_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF861 domain-containing protein"
                     /protein_id="HDF3911971.1"
                     /translation="MDISNIDKNLIETLVRQIIEEKISGTKDTVDFVRNKDISGITSI
                     KLPTVKVSESDRLDTGNPSDVVYTKDLFTLEESPRLGCGMMEMKETTFDWTLNYDEID
                     YVIDGTLDIIIDGRKVSASSGELIFIPKGSKIQFSVPDYARFIYVTYPADWASQN"
     gene            complement(27559..27660)
                     /locus_tag="PC494_001467"
                     /pseudo
     CDS             complement(27559..27660)
                     /locus_tag="PC494_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433047.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
     gene            27955..28476
                     /locus_tag="PC494_001468"
     CDS             27955..28476
                     /locus_tag="PC494_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HDF3911972.1"
                     /translation="MEEIVKKEQASMNDIFLYLKAKSNSLYKFVILYNEFINKPKDYG
                     TGELINMVEVHMLTAIEENPGISPTQLAKIWNRTKGAISQTISKLEKKGYITKEKKEG
                     NAKTILLYPTTSGVELSKAHKLYDTIDVTRTFEYLIKECTLEEIDSFYKVIDLFINLL
                     EESPQENNDSEKV"
     gene            28855..30030
                     /locus_tag="PC494_001469"
     CDS             28855..30030
                     /locus_tag="PC494_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HDF3911973.1"
                     /translation="MNLKQLSEKYEEYVIQMRREFHKYPELSFKEIRTTQRIREELQK
                     IGVPFVSIEPNIVIATIQGKNEGKTIAIRGDIDALPMQEDSDVEYKSEYDGIMHSCGH
                     DAHGAMLLGLAHMLNDIRKDLKGRVLLVFQAAEEVGGGHKEIIQYFKENGGPDRLIAT
                     HVWSDIEAGKISVEPGPRMAGGSGWRIDITGRGGHGSRPDQSIDPIKPACDIVLKVSS
                     IPVNHISVLEQCVVHACAIHGGTTIGNVIPNNAEVIGGYRYFTEESGKKVFDIIKQMS
                     NGVGQVYGVDVKVTHTGGIGPVINDEEAVKMAKEIVSNIDGLELDSYEPICASDCYGE
                     ILKEYSGFYCYLGVGNKEKGIIYAQHHPKYNIDEDTLKLGCEFMAKYAVEFLNKNNN"
     gene            30065..31603
                     /locus_tag="PC494_001470"
     CDS             30065..31603
                     /locus_tag="PC494_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbgT family transporter"
                     /protein_id="HDF3911974.1"
                     /translation="MQGALKENKKKSGGGFLGWIEKVGNKMPHPLALFTYITLIVVAL
                     SAIASFLGFSATSPATGKLIKVMNLISAKGLVLFMQEFVKNFQNFPVLGVVLVMAVAT
                     GVCEKTGFFSTAIKMSLSKVKGNAVVFIIAFIGVFANQAGDAAFVLVPTLAGAIFYGL
                     NRNPLAGIFCGFASVGGGFATAVIPGGWDVTLTPITVSAAQTIQPAFDMTLLASYYAL
                     FVSAFIVATVSTIVTVKFIEPKLGKYTGKPEGIDDNQGFEVTKEQAKAAKLAGFTVLA
                     YVALLIALCIPANSFLRSPEGSLIFGAPLMSCLQFFIVILFFLPGIVYGMRVGKIKTV
                     KDLNDILCQSMAAMAPFIVLAIVIGQFLTLFSVSNLAQVLAIKGGALLNSLPLPPQAI
                     ILLFLVLVAFINIFVISGSTKWMIFGPVFVPMLMQLNIHPAFTQFVYRLGDSVTNHLS
                     PLNAFFIILLATVQKYDKNAGMGTIFSAMIPYTIGYFVVLAVLVVVWMTIGIPVGIGG
                     QVWL"
     gene            31635..32837
                     /locus_tag="PC494_001471"
     CDS             31635..32837
                     /locus_tag="PC494_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HDF3911975.1"
                     /translation="METTEIRYNFDEVIDRSGTNCLKYDLKSQFMPESPEDALPLWVA
                     DMDFACAPEIINAMHERIDRKIFGYSSQQTDDYYEAVCGWFKRRFDWKIEKENIFFSP
                     GVVPALGFFTQILTQKGDGIIIEKPVYYPFEDKITNNERKVVNSPLKFEDGHYSMDYD
                     GFEELAKDENNKVFILCSPHNPVGRVWKKEELRKIVDICKKYDLWIISDEIHCDIIRK
                     GEKHIPLEVACPDYKDRIITCTAPSKSFNLAGMQLSNIVINNKELQKKWMLETDSKLA
                     IFLPNPFAIVATKVAYNDCEDWMNQVNEYIDGNIKYVEDFVNEYMPKVKIIKSQGTYL
                     VWLDFRGYGLDAKQLEYVMLNKAKVLLDEGYIFGEEGAGFERINVASPRTIIEECMNR
                     IKCAFEGL"
     gene            complement(33004..33603)
                     /locus_tag="PC494_001472"
     CDS             complement(33004..33603)
                     /locus_tag="PC494_001472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDF3911976.1"
                     /translation="MNDNIVEVKNINMNFYTKEGELEVLKDVNFNLKEGEILTLLGPS
                     GSGKSTILNILTNLLKPTSGDIKITGNIGYMFQKDNLLEWRNIMDNITIGLEIQGKKD
                     KKSLDRVESLLKTYGLWDFRSMYPKELSGGMRQRVALIRTLSVNPDILLLDEPFSALD
                     YQTRLLVCDDVYSIIKNENKSTILVTHDIGEARCIKVQL"
     gene            33773..35131
                     /locus_tag="PC494_001473"
     CDS             33773..35131
                     /locus_tag="PC494_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3911977.1"
                     /translation="MSNIITNLIESIFTNPITILFLLAITVYSVFKIIENNRVYSFVS
                     SKLDEINRDYKTSEFYKKVRDDYYTYSKENPYADVNITSFIEEVVSDLKHNNLPLLEK
                     IRSIKNSSSISILLGVLGTFVGLSTMLLCVDTKDIINSLPSTISSMQTAFTTSIFGVV
                     FSLIIGYFTKIKDCEHVLIQIMLKSENLLTSEITHFKSERMDLKVEEVKNTIKQISKS
                     IEAIEKFDKISKDLNDFNDEFISGIEALKSLLEGSQSSIKTFDQSVRKLDKQFNILNI
                     KFVKLFDKYDNQDNINKEILFDIKESSKNIYNATESQFKIRDYIKNINAGFALYERSA
                     QDLLTKLMTHENKISQNQKILLDEKFTLDDSIKNLSSIIENFSNDLQVKLDMMFENSL
                     DIQDKLDVMFNNSFMNDEVPLDSEELFKDDVNNVFNPFSEEIYEIEDKEIKVIGEDEL
                     NE"
     gene            35124..35756
                     /locus_tag="PC494_001474"
     CDS             35124..35756
                     /locus_tag="PC494_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OmpA family protein"
                     /protein_id="HDF3911978.1"
                     /translation="MNNKYRRTVNREFEKSSFWPTFTDLLSTVLMVVILILFSSESIS
                     GSVEQDLAKNVNASVEETFKKSGIPVKVDKSNGQVTFGEKTMFDVDSDVLKPEAKEML
                     KMFVPKYIETIYKDYGDYISKIVIEGHTDDVGSYIYNLDLSQRRAYSVAKFIVGDEIG
                     DYKYKDKVTKHIIAIGRSKAELIKNGDNSVNRDASRRVELKYEININQNK"
     gene            36085..37242
                     /locus_tag="PC494_001475"
     CDS             36085..37242
                     /locus_tag="PC494_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HDF3911979.1"
                     /translation="MIEISIKNKKNSKIKTLILLLIVSISIYLTGCTTSDNGNNQSNN
                     NDSLSSSISSDKNVKIHFIDTGNSDAILIQDGKTFTLIDGGDNDDEGLMVDYLNNQGV
                     KDIKYLIATHSHADHLGGLDSVVKNFNIENVFVSNGSAETKSYRDFINALANKGLSPS
                     VPLENNKFYLEDSYFEVLNTNGGDTTNEQSLVLVYTNGNDKVLFTGDAEEGTEKEILP
                     KLEKVDLLKVAHHGSRSSSSQEFLDKVNPEYAVLLVGKGNSYGHPHQETMNKLKKMGV
                     KVHRSDECSDIIFESTGDGVFTSCKDGSYNKGVREDGNSGKSNSNTSKNDSFKNKQNT
                     SNSEEIVYFTPKGKSYHSTKNCSGLSRSKKILSGTIAESKKNDPCDICYGK"
     gene            complement(37389..38024)
                     /gene="lexA"
                     /locus_tag="PC494_001476"
     CDS             complement(37389..38024)
                     /gene="lexA"
                     /locus_tag="PC494_001476"
                     /EC_number="3.4.21.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor LexA"
                     /protein_id="HDF3911980.1"
                     /translation="MYLDLTEKQVLILEFIKSQIILKGYPPAVREICTAVGLRSTSTV
                     HSHLNKLEKLGYIRKDPTKPRAIEVLERSKVNDVSGANQEIIELPLVGQITAGEPILA
                     QQNIEEYIPFPASLVKGSNNFVLRVKGESMINAGILDEDYVVVDKKNTALNSQIVVAL
                     INGESATVKRFFKEGNLIRLQPENDFMEPIMLNDSEVEIVGIVTGVFRVIK"
     gene            complement(38128..39255)
                     /locus_tag="PC494_001477"
     CDS             complement(38128..39255)
                     /locus_tag="PC494_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HDF3911981.1"
                     /translation="MNNDKKIIKVHNKSDKPDNIVIKENELIEKCLLLENKLPVFMKD
                     YFIYLKGSVAVSTRLAYLEDINFFCSYLIETKELTNADCVKDITEDDFNTIKSRDINL
                     FLGDYCSRYYKNTEKNTLIFENNNRALARKKSSISTLFKFLYRNSQIDNNITDGFNPI
                     KLPKPQPDAIKRLEIDEVAKMLESVETGEGLTEKEKVYWRKTKLRDKAILALFVTYGL
                     RLNELRELNISSFNFSRGEFKIYRKRGKEVLMPINHTCEHVIKDYLQNERTRDELLND
                     EEKDALFLSLQNKRITAKAIRTLVKKYTSIPLDTTRDNGYSPHKLRATAATSLIQTGF
                     SIYDVQNLLDHDNVTTTQLYAAHKKNVKRDIVKNFEWIEDD"
     gene            complement(39539..40384)
                     /locus_tag="PC494_001478"
     CDS             complement(39539..40384)
                     /locus_tag="PC494_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3911982.1"
                     /translation="MIYIIEILKISVINIFCFIGIFIVFGLIFSITENLNNKFIFSSF
                     GKTGIIVTGAIGTFVHELSHLIMCLIFMHKINSVKFFRPIESKNDGILGYVSHSYKKD
                     NLYQSIGNFFIGIAPIIGGTIMIILIFKILLPDSYMKVTQNIDLKLYVSMINNLNING
                     FIHIILGDISNFIRIMLLTPSVYSLKYFIFMFLMYSISTHMSLSSADLKNSLNGLSFI
                     VIVIFVISSITYLFGFDNLNISSLIVKYNIFISFFMAIGFIFSIVTLIISYILSLVSP
                     FKNFS"
     gene            complement(40414..40785)
                     /locus_tag="PC494_001479"
     CDS             complement(40414..40785)
                     /locus_tag="PC494_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HDF3911983.1"
                     /translation="MKLKLLVEEYAVCRLNNDSKIPTWIDTEKFYSITRTDDELSVVC
                     LNNNIPSDVKSEKEWRILKILGPLDFSLVGILSKLSSLLADNKISIFAISTYDTDYIL
                     VKEKDIENACKILSCNGYEVE"
     gene            complement(40938..41198)
                     /locus_tag="PC494_001480"
     CDS             complement(40938..41198)
                     /locus_tag="PC494_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003866776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein S"
                     /protein_id="HDF3911984.1"
                     /translation="MEVLKVSSKSNPNSVAGALAGVLRERGVAEIQAIGAGALNQAIK
                     SIAIARGFVAPSGMDLVCIPAFTDIEIEGDKKTAIKLIIEPR"
     gene            complement(41387..42331)
                     /locus_tag="PC494_001481"
     CDS             complement(41387..42331)
                     /locus_tag="PC494_001481"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit alpha"
                     /protein_id="HDF3911985.1"
                     /translation="MIENNSEKIKILENDIKQLITISKANNIDLSDKINSLNEKLEKL
                     KEDAFSHLSAYEKVTLSRDIKRPTTLEYIEHICSNFLELHGDRLFKDDPSMVGGIGQI
                     GKFNVTIVGHQKGRDTKENIKRNFGMPHPEGYRKALRLMKQAEKFNRPIITFIDTSGA
                     FCGLEAEERGQGEAIARNLLEMSKLSVPVITFVIGEGGSGGALGIGVGNDVCMLEHSV
                     YSVISPEGLSSILFKDSSKAKEACDVMKLTSNDLYDLKIIDKIIKEPLGGAQKDVEAV
                     SKEIKAYILERLNHYKDMDKEEIIAQRYKKFRNIGKCL"
     gene            complement(42352..43206)
                     /locus_tag="PC494_001482"
     CDS             complement(42352..43206)
                     /locus_tag="PC494_001482"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit beta"
                     /protein_id="HDF3911986.1"
                     /translation="MIKKFLSSKESKYVTISLDDNFKKNSVDDKFWTYCKGCDSHVFR
                     KDIEENSFVCPKCSRHYGLRARKRINLLIDKGTFMEFNSDVEFQNPLNFPKYKEKVDS
                     YKEKTKESEAVVTGYGRINGIKTVICVMNPDFMMGSMGSIVGEKITYSIEYAAENNLP
                     IIICSASGGARMQEGMVSLMQMAKTSQALSKLEEKSLPYISVLTDPTTGGVTASFAML
                     GDIIISEPNTLIGFAGPRVIEQTINQKLPEGFQTSEFLLEKGFIDMIVDRRKMKEVLY
                     QILAMHKK"
     gene            complement(43221..44582)
                     /gene="accC"
                     /locus_tag="PC494_001483"
     CDS             complement(43221..44582)
                     /gene="accC"
                     /locus_tag="PC494_001483"
                     /EC_number="6.3.4.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HDF3911987.1"
                     /translation="MIKKILVANRGDIAVRIIRTCKELGIKTVAIYSEIDKDCFHRYI
                     ADESICIGPNNISKSYNNIENIIYLALKLKCDAIHPGFGFLSENPEFAKQCEDNNIIF
                     IGPTREQMILMGDKSRARETMMELNIPVVPGSESVLKTKEEALEVAREIGYPVMIKAS
                     SGGGGKGMRIVRKEEELFSNFDMASSEALAAFSNSDLYMEKFIENPRHIEVQVFGDKH
                     SNAIHLGDRDCSMQRRNQKVIEESLSPYLSDEERQKLHKIAVDIVKGVGYIGAGTIEF
                     IVDKDKNFYFIEMNTRIQVEHPVTEMVTNLDLIKLQISIANGDKIPFKQEDITFRGHA
                     IECRINAEDSSKNFAPSPGKIESLNLPGGFGVRFDTFVYAGYTIPPLYDSMIGKLICW
                     AETREECISRIYRALDEIIVEGINTNVEFQKALVTSEEFREDTHHTKFIEDVFMKKEF
                     ATL"
     gene            complement(44598..45050)
                     /gene="accB"
                     /locus_tag="PC494_001484"
     CDS             complement(44598..45050)
                     /gene="accB"
                     /locus_tag="PC494_001484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HDF3911988.1"
                     /translation="MNINEIKELLKAIDSTNLEYVKLESSDLRLEVSKKAQSTSSPVL
                     SVQQESVVDLSLEKPVVNDTPVTSNENLSVVVAPLMGTFYDSPSPDADSFVKVGDVVE
                     EGDTLCILEAMKLMNEITSEIKGEIIEVLVSNEELVEYNQPLFKIKPL"
     gene            complement(45320..45766)
                     /locus_tag="PC494_001485"
     CDS             complement(45320..45766)
                     /locus_tag="PC494_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3911989.1"
                     /translation="MESKFFNWYTQSLGGTFGIISCICAYLNGYMFVYTNSASKYFES
                     IGFLGIISSYTLLPLCMLTLIFGVIYSYTPETSDKSIFNIPFFTLNKRLILITVVFGF
                     IGARVYFIIPAILITFNLYSNVLIAKLKYILCKNKENDTNLKESEV"
     gene            46041..46319
                     /locus_tag="PC494_001486"
     CDS             46041..46319
                     /locus_tag="PC494_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3911990.1"
                     /translation="MVDTLEFGLKILFFILSIIWMGKIMILRTDKQIVINPLLIGISA
                     VLVMLHTSQSNIEFFGLDVQYIRIVLYIIYSLIILIGIWATNRRNGIF"
     gene            complement(46448..47194)
                     /locus_tag="PC494_001487"
     CDS             complement(46448..47194)
                     /locus_tag="PC494_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3911991.1"
                     /translation="MWEGTMNLANLIPFIISAAALSPINSNDKVLSENQLKDIFPDAN
                     LRAVVKRYINPDEMTISNIKALDGEFYATGESISNLKGISYLENVDNFIFWNNNIKEV
                     PKEALSLKDMDSINLANNYLIDDDVVNSLSHNGVDVNCDLNFIDTKDNQYKLDSKYHN
                     VDIAKGESIDLRKIITKKIDSYYKYWEVTDNLPKDLNFIVSVSDKSVLSCEDMIIKGN
                     KTGQAVVKVILSDKNDLNTSQEVLITVNVK"
     gene            complement(47323..47967)
                     /gene="trmB"
                     /locus_tag="PC494_001488"
     CDS             complement(47323..47967)
                     /gene="trmB"
                     /locus_tag="PC494_001488"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HDF3911992.1"
                     /translation="MRRRRKKGADEKLLSYTKYVLRDDIDKLKGKWNLKFRNDNPIHV
                     EFGTGKGKFITTLAKQNPDINYIAMELKEEVLLKAVEKADASNLNNILFLWGDVSNIL
                     DYFEAKELSRIYINFCDPWPKNRWSKRRLTHSGFLEMYNRVLEDDGEIHFKTDNEKLF
                     EFSLNEIAANNWLLKNISLDLGNSEYENNVTTEYEDKFMSQGMRIFRCEAKKRN"
     gene            complement(48105..48425)
                     /locus_tag="PC494_001489"
     CDS             complement(48105..48425)
                     /locus_tag="PC494_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein HesB"
                     /protein_id="HDF3911993.1"
                     /translation="MKITLPETAIDTLKSILKDNQDKPNNIRVYFAGVGCGGPSFGLA
                     LDEKKEDDLTYEVGELQFVMSSDEYSQYGDIIIEDTGFGFRVIPENMKDQGGGGCSGC
                     SGCH"
BASE COUNT        18382 a         6414 c         7408 g        16384 t
ORIGIN      
        1 atattttgtg tttagtagag tgttgctaag tgaatatatt taaaatggag gaaactttat
       61 gaaacaaaat aaatatgatg atgatagatt ttttaataag tacagtaaaa tggaacgttc
      121 tacaaatgga ttagcaggtg ctggagaatg gcatgtttta aaaaaaatgt tacctgattt
      181 caaaggaaaa agagttttag atttaggatg tggatttgga tggcattgtc aatatgcagt
      241 tgagaatgga gcaatttctg ctgttggagt tgatatttca gaaaaaatgt taaaagaagc
      301 tagaaacaaa acgcaacttg ataatataaa ttacatatgt atgcctattg aagatattaa
      361 ttttccaaaa gatagttttg atgtagttat tagttccttg gcatttcatt atattcaatc
      421 atttgaagat atatgtaaga atataagtaa ttgtctttca aataaaggta attttgcatt
      481 ttctgttgaa catcctatat ttactgcata tggaagtcaa gagtggtact gtgataaaga
      541 tggcaataat ctacactggc cagtagatag atattttgaa gaaggagtac gtaggtcaaa
      601 ttttctagga gaagaggtta taaaatatca taaaacatta acaacttatt taaatacgtt
      661 aatgaaaaca ggatttgaaa tattagaaat tattgaacct caaccagaag aaaaactgtt
      721 agatacaatt cctgatatga aagatgagct acgtagacct atgatgttac ttgtatctgc
      781 aaaaaaaaga taagtaaata taaataatca ttattgtaga aaaaaagttg tagaaaataa
      841 ttacactaat ggagatgatt ataccagtgg tattaattac accagtagta aggaggcaaa
      901 agcattcgtt gcttttgcca ttttttaagt tgcaattata cttctacgta gtatatttcg
      961 tttccatttt cttctataag ctttttcata tcttcaaatt ttaaaaatac agtagcagta
     1021 ttatcatttg gatgtatacc tattttatcc atttttaata aatccttatc aaatacaact
     1081 tttacaacag cctctttatc atttaatata ccaaaaggag tcacagctcc tttagtaagt
     1141 ttcaagtatt tttgaagtct ttcttctgat gcaaaactaa gaggtttact atcaatttgt
     1201 tgacgaatat cttttaaatc tgcttttttg tctttaccta atacaactaa aaaatgttct
     1261 tttcctttag catcacgaag aaataggttt tttacaacaa attccatatg taatgttttt
     1321 aattcttcca tttcttcaat tgtataaact ggtggatgat ttacagcctc ataaggtatg
     1381 cttaactcat ctaatttttt atatacttcc tgttgttgat tgttcatgat ttcctcccat
     1441 tagaaattta ttttatatat aaataatatt atcacagaaa actttaaaag aaaacgtttt
     1501 atataatata gacaatagat tatattttta taaagaagca agaatactca ataaaactta
     1561 aagaaattaa acaatttcta aaaatacctt gaaaatagaa ccttatttgc catttataaa
     1621 ttatataaaa agggattata taaagtcata tatgaaaaaa ctatattata ctatcttttc
     1681 tttttggaat aaactatact ttaaatatag atatttaatt taaataaatt ttacagtatt
     1741 aatagtaaat tatcttagaa aggaatgtgc tttatatgtc tacagacaaa gttgttggaa
     1801 tcatagatga agaaacggca gaacttgcag gaattgaata tactggtaaa atttatgctt
     1861 cttctggtgt tataaaacat ataaagaaaa aacatagatg tcaactgagt aaggatattt
     1921 ttaatgatat aatagatact ataaaaatgg tattaaagtc acctgaatat ataggaagtc
     1981 atcctaaaaa acctggaaaa agtgtggagt ttataaaaaa aattgatgat tatattttag
     2041 tagctacaga attagataca aaaaaaggat atttatatgt atcttcaatg tatgctataa
     2101 aagaagcaaa attagaaagt agagtaaaca gtggaagagt aaaacaatat gatggttaac
     2161 ataatattat taattttccc taaaatattg aaaaatatta ttatataagt tataatatta
     2221 atatacacgt agatatttat tagttagatt tgaggttgga aaaggcaccc aatacgctac
     2281 tatagagtag ttaatagaga tgcaggatac gccgccctgc caaatctaat taaattaaaa
     2341 agagaggatt aattcctctc ttattgtttt tttgagatac taatttaatc tatatagaaa
     2401 gattgaaggt catttatact aaaagttttc agttatatac attaaactaa ttaaataaga
     2461 tatttataat ctatatgtga tacatattat atattaataa aagaaaaata tatagaaaat
     2521 ccttataaaa atttaaattg taatgaatag gaagtaatta aaaagaattt ttattgattt
     2581 ttaaaaattt agttagaaac tatatcatta tggtaaaaaa tgtattataa tgtttagaaa
     2641 tattataata aggagcgatt aaacatgaat ctaacgaaga aaatagaaga taaaagaaaa
     2701 gctaaacaga gagctgaaaa agttaagaaa gctaaaattg ctacagctgg tgtggtatta
     2761 ggagctgtta ctggtgcagt gagtggagta cttttggctc ctaaatctgg aaaagaaaca
     2821 agagaggata taaaagatgc ttcacaacaa attgctgaaa agataaatat gaaaactgta
     2881 gatgtaaaag gcaaagtatc tgagaagcta gaggataaaa aaggaaactt tatagaatca
     2941 aagaaaaaaa taaaaaaata tatagataac aaaaagagtg ttgaaaattc tagtgaggaa
     3001 gataaaataa tagatatagt tgaaccagtt agtgttactg aggaataata tggacaatac
     3061 aataacgatt aacataagta taatatatgt attattagct atacttgctt gtattgcttt
     3121 agtttattta attattgtac ttgttaaact acataagatt ttaaataatg ttggaactat
     3181 gttaaatgaa aatactcaaa atataaatac aactttaaat aatcttccta atgttgtaga
     3241 aacttttgga gaagtaggag aaaatatgaa agatgtaaca gaagtagtta ctgaagttac
     3301 agcagatttt cttgttacta aagacagtgt caaatcaaat atggatgtta tagttgatat
     3361 attgactata attaaaaaca tttttctaga taaaaaataa taagttaata taaaataagc
     3421 ctataagata taatttaaac gaccttaaaa tagcatttat aaggtcgttt tttattagct
     3481 tgatttgaca ctatgtgttt ttaataattg gtaatattcc tctttatcat ttgaacatat
     3541 atatctatgc ttgttgtttc aattacatcc ataagaacat ctttacattc aagctcaaaa
     3601 tcttccattc cttctaaata ttcatcatct tcatcaaaaa agatataaga attatatagc
     3661 cattcttcaa atttttcttc aagtatatcc caatacgaac tccaaaataa tccacaacct
     3721 gatatataag atgctctact ttgatttata taaacctcat ttagaagctt ttgtaatcta
     3781 ctgctataaa gaaaatctgc tcttccactg cttgatatta attcatttaa atcttctatt
     3841 gacattaatt caactttacc acttttatca taaggagtat aattttcatc aacccattta
     3901 tgtggtttgt tttctctgca tactgttgct atcaactcta caacttttgt tcttatcatt
     3961 tttttatcct aacttattta ttttttataa aataatcatg attttataat ttatctattt
     4021 cttgtaatgc taatttaaca gtttcatatc tatcagcacc atttattact acatcacctt
     4081 ttacaagttt attagcttct ccacctacaa cataaacctt tttacctaaa ccttgcttat
     4141 aactagacgc ctcaattatt aaagaatctt tcaattgcca atgtaaaatc tgagcagcca
     4201 ctttatcagc atcacctgta taaacgatta cattttcata cactttattt tcccctcccc
     4261 cttgagaatt tgatatagat ttgtttagta taccttctgc tatcaattta gcaactttat
     4321 ctttattatt aacataataa tctgtatctg ctttactatc tacaaaacat acttctatta
     4381 atattgctgg tgcaatagta tgattaagcc aataaagacc tctaacatca gactttgcac
     4441 ccctatcttt gaatactgta gctaacctag tattcactct ttctgcatag gttttgccat
     4501 tattagtctt atatattgtt tctgtcccta ctggagttga agttgtagca tttgaattaa
     4561 aatgaatctg aacagccaaa tcagtttcct gtttatttgc tatagcacat tggtctgcta
     4621 aatgattact tgattcatca actcttcctg tataaacagt agctccacct attttaagcc
     4681 atttaacaat taagtcattc agtattcttg tttctttgct ttcgtttata tacccaacag
     4741 ctcctgtacc ttttccaatt aaagtgtgcc ctggtattat tactactttc aaactaacat
     4801 ctcctttaca attaaattta acttctattt aatatatgca taacctagaa ttttgtttct
     4861 ttttatatct tatactttta ttataaccta ttttgtaaaa atatagaata ttaagtaaat
     4921 aatgttaaaa ttataatttt gtatataaga cattacttga ttgcaataat tttatagcat
     4981 attcatctat tctatatcca gttctataat atatatgttt aattccagct tgaattatag
     5041 ccttagtaca atttaagcaa ggaaagtgag ttacataaat agagcaattt ttaactgaaa
     5101 taccttcttt tgcacaataa taaagggcat tttgttcagc gtgaatggtt ctaatacaat
     5161 gtccatctct catttcatga ccaacttcac tacaatgctt atctccagaa atactaccat
     5221 tatatccagt agacactatt ctgttttctg aattgacaat tatagctcct acataagctc
     5281 tatcacaagt tcctctttca gctactgttt cgcacagtct cataaaatat tcttgccatg
     5341 agcatctatt ttcaagtttt ttattcaaat tatatacctc caaaacttat atctaatata
     5401 taagatttat accttaaaaa taatattaaa aacaaattta tacgataaat aaaatttatt
     5461 aatactgttt ttagtctaaa ttatttcatt ttaaattaaa gttacaagga atctaaaatt
     5521 atatatatct ttcttcgtaa tattaatgtt acaatataaa aaactgtctc aataaaatag
     5581 agacagtttt acagtcaaag tttataatac aagttcatat ttttctttaa attcttttac
     5641 agcttcgggc catgcctttt gttctgtaat acctttttct ttagctattt taattgcaat
     5701 ctctcttatc attgcagcgc cttctaatat tcccattttt aatctccctt caaatatctt
     5761 tttgtataga atataaatag tgctaagatt tattacatgc tgcatataca atatctatac
     5821 aacacataac ttgtaaattc cttttatttt catacgtctt taaccgacat ataattatat
     5881 tcaataagtt ttaaaattat gaactcaatt ataattattt ttattttttt agaatctaaa
     5941 cactaaaaat tgtaggtaaa tttgtcttat gcctttataa atatttctac agttttaatt
     6001 actggacata tctattttta ttataaaaag cgcttaaaaa tcgagaatat ccgcataaaa
     6061 actgtatata agcaaaacgg ttaaaggaaa aagaagaaat ttacttgaat gttaaaatgc
     6121 gttgcttgaa gcaatgggca gttttgccta taatatcggt aacaactgaa agaaaggtgg
     6181 ttagccctaa tgttaagcga aaacattaaa acaatcagga agtcaaaagg actttcacaa
     6241 caagaacttg ctataaaact gaatgtagtg cgacaaacaa tatctaaatg ggaacaagga
     6301 ctgtcagttc ccgattctga tatgttgatt tccatatcag aggtgcttga aacgcccgta
     6361 agcactttac ttggagaaac tattgttgag tcggaagttg atagcttaaa agtgatttct
     6421 gaaaaattag agattataaa cttgcaactt gcacaaagaa aaaacatgag aagaaaaatg
     6481 tttcattggt tatttatttt attatgtgca gtcatattaa taggttttgt ggtcttaggg
     6541 ggactaaata gtccttactt ggattggaat tataccgacc ctgaaaccgc tgtttttgga
     6601 gtagcttttc atgcttttga gtggctattt gtcagattag taccgattgt ccttatagga
     6661 gcaattattg gaatctttgt gacacgtaag aaaatatgaa gtaactctgc tttttataat
     6721 acagcaagcg ttccttaaaa gcgtcattct acatggcaat cgaggacgac tatgtaagga
     6781 agaacctttt tgatttccaa ctaagcgaag ttattgagga cgacagtaag accaaaaccg
     6841 cattaagtaa agtacaggaa gcaagactgc tggacttata ctctcatgcg tcagatgcag
     6901 gaaatgcgag gtctggtagc atgatttaca acgatttgta caacgactgt gagtagaaat
     6961 atatggagat aagtattatc tacgaaatca gaaaagaaat gacttgataa tttactcatg
     7021 ttataattat tgatgtgaaa ttaataaatc gaaattcctt ttttggattt aacaatactg
     7081 agtaaggaaa aagtgaatga cttttgcaag gaggtgttaa tatcaggcaa gtaaagtctt
     7141 ttgtttttcc agttatatcc ttaatattct tagaccaaat tagcaaagtt cttataggat
     7201 tattcttaat ggactttgaa attgatataa ttgggaaatt tttaagattc aatcctgttc
     7261 aaaatacaaa tctctcttat gggggaaact ttattggtat tctatctaat ttatgggtat
     7321 tggtattgtt taacatttta gttatattag ttattatatc tggatatgct ttttataaat
     7381 caaaaaatga acaaacaagc tattcagtaa aagtaattat gtcttgtgga cttgctggta
     7441 caatatgtag cttgatagat aaattatttt ggggaggaag tttagatttt ttgcagatac
     7501 caagcttttt tattttcgac ttaaaagact gctaccttac tgttgcagaa ataatatttg
     7561 ttgtcatagg aattttgcat aatagagaaa tatcaatgaa agaatacata tatttttgct
     7621 atcgtcagtt taaaaaataa atttagaaga taaatttaag tttcaaggta aacttattta
     7681 atcacagcaa atagttggct tacttaagct tttgggctaa actgtgagaa ctaattaagt
     7741 ctctgctatc taacaaacag agcacaaaaa taaaaattaa atattaaata taaagcacag
     7801 ttaattttga ttaaaaagtt gactgtcttt tcttttgtag aaatttaagc ataggtaata
     7861 aagaaatgac tgcatttaag cattatgtat ataattggag gcaataaaaa gccagcaaag
     7921 cccataaaat agagctgtgc tagcaacatg atgagttata agaagataat caaaaactta
     7981 cgctttattt taatttaaaa aaatgattac tgtaaagaaa tcatttttta ttataatcac
     8041 tgatacatca aatattctaa ataaaatttt tatttatctg gaattgtata ttttttctat
     8101 aatattaact acagcgtaca ttgcccaagc acagatagcc aatacaaata ctcccatcat
     8161 tactaaatct aatttaaata cttgagaacc atatactatc aagtagccta ttccatatct
     8221 tgaaactaaa aattctccaa ctattacacc tacccatgcc ataccaatat taattttagt
     8281 taaatttatt aaatttcctg tgtttgcagg taatatgagt ttaaataata tttgagattt
     8341 agtagctcca aagcttttta acatcttaat tttttcttca tctatattca taaaataatt
     8401 ataagctgaa agtatagtaa caacaacaga aatcgttaca gctgttacga cgattccttc
     8461 tattccagca cctacccaaa ctataattat aggagctaaa gcagtcttag gaagagcatt
     8521 taaaactacc aaaaatgggt ctaatatttt tgataatttt tctgaccacc aaagagcaat
     8581 tgctaccaaa atacctaata cagtacctat aacaagacca agaacagttt catatacaga
     8641 tattccaata tgtttaaata attgaccact aaatgcatat tgaataaata aattgtaaat
     8701 atcacttggt ttgctaaata gaaatgtatt tataacattt aagtcagcta aaagttccca
     8761 gattacaata aaaccaatta aaattaatag ctggtagaat aatacatttc ttttttctct
     8821 ttttacacct ttaacatagt ttatatatcc ttcagatctt ttattaagcc tcatgtgtat
     8881 ctagctcctt ccataatatg tcgaaatact tttgaaaatc aggaacttta cgtgttttga
     8941 gaggcgtttt tgttccatcc atgttaagtt caatatcgta aatatttttt atggtagctg
     9001 gtcttttaga tagtattgca accttatctg atatgcttat tgcttctgct atagctaaaa
     9061 aagtgcaact aattgcttaa agaaacagaa ttatccactt cagcacccat ataaacaata
     9121 ttaagatttc ctaaactgct atcccaaacg atactattaa taatagtaga taataacaat
     9181 ctcttatcat ctaaactggc attatcaact tcatcattaa atctcttcaa attactaaca
     9241 ataatatcaa tattaatact gtcactacta atattgatgt tactagattc caaaatatta
     9301 atcttatcct ttaaaatact aatctcatta tttaggctct caatctggga aactatataa
     9361 tcagaagcag tactaccagt attttttgca agctctataa ctaaattttt aataagtctt
     9421 tccttatcta aaatttgatt tttaagtaaa ttagtctcag atttaaaaat attaaaaaca
     9481 ttatcagtct taatgttatt actattgaat gcacttataa tagactcttc tttacaattc
     9541 ttaattttat ctataactaa actttcaact aatggaccat taagattttt acagttgcaa
     9601 ctatcagacc caagtgtttt tttagtacca caaatataat aatactttaa atccttgtca
     9661 gtttttttgc ctttataggt aattctcata ttagaaccac atttaccaca ttttataaga
     9721 ccagataaaa gagcagtttt tccagttgat atccttggag ttttatcacg atttttatct
     9781 aattgatttt gtacttcaag ccatatttca ggttctatga ctccatggtg ttttgcaatt
     9841 gctgctattg agttagatgt atttttagca taagtaagga ttccacattt tctatctgga
     9901 gtacctacaa catccatacc actattttta aggtaatcta aaatttcatc attagctttt
     9961 acatatgctg gatttctaag tattctagat aaagaactag ggtcaaattt accaccacga
    10021 ggacccctta ttccattatt atagacatat ttatataact tagataagga cctaagttct
    10081 aaatatttat tgtatattag ctttacaatc tccatttgtt catcatttac ttgaagctta
    10141 tacatacttc tttcttttag attttcatct aagaatgtga ttttttcact gttgaatcca
    10201 tgaggtgtat tgcctccaag ccatctacca ctacgggcta attcatacat attgtctttt
    10261 atacgttctg ctattgtttc tctttctaat tgagcaaata cacttgatat aaacatcata
    10321 gctcttccca ttggagttga agtatcaaat tgttctttga tagatataaa tgatatgttt
    10381 agttcattta atttttctat taaagtagag aagtcagata catttctcga tatcctatct
    10441 aatctataac aaactaggta actaaatttc ttatctttgg catcctgcat cattttctta
    10501 aattgtggtc tatctatatt gctaccacta aatccctcat cttcatatat caaaaaatct
    10561 tttacaccaa tagactttgc ataatcaata cataattgta tttgattttc tatagaatca
    10621 ccttttccag taaatcttga ttttcttgaa taaattgcag ctttcaaaat taaaaccccc
    10681 tataagttag gatatatatt tgaaattatt tatatacaac cttttaagta aacttattag
    10741 aatgaattta ttaattaggt aaatttatat aattctactt tttataatat atgactattt
    10801 attttatttc tttactattc aagttctaaa tcaataataa attttgatat ttaattgtat
    10861 caggacaaat ctctaatttc atagattatt aatataaaat cataggttag tgtgaaaaag
    10921 ttgaaattta aatattttaa aagataattt ttttgaacta ataggtataa caaaaattta
    10981 tagggggatt gcatatggaa atcaatgtta tagaaatttt ccctaaagat aaagctaaac
    11041 ttaataaaat agaaatggat aaagctagtt ggtttgtaaa tataataagt aaaaaatatc
    11101 ctaaagaagc tttaaatgaa gcatttagta ctttagaaaa agaattaaat ataagtaaag
    11161 ctaatacata agctttgatt attgatttta tatactattg gttttatacg ctatgacttg
    11221 acattatatt aatcaaatag tatattttta aatatagcac aatgaagtgt taaaagagca
    11281 atggagctcc atagataaag tctatggagc ttttttgcgt atttaactta aggaggatag
    11341 gactttgaat aactttgaga ttaaaactag aataaaattt ggagaaggct cactaaaagc
    11401 tttgcaagaa ttaaaaaaca aaaatgtact aataataaca gaccctttta tggtgaaatc
    11461 aaaaacaata gataaaataa catctaattt aataaactca acatatcaag tttttgaaga
    11521 aatagtacca gacccaccaa tagaagtagt agtagcagga atagaagcat ttaaatctat
    11581 aaatccagac gtaataatag cattaggtgg cggttctgca atagatgcag caaaatctat
    11641 aatggacttt tctaaaaaaa tattaaaaat taacgaagta gagtttatag caataccaac
    11701 aacaagtgga acaggttcag aagtaacatc atttgctgta ataacagata gtcaaaaaaa
    11761 atgtaagtat ccattagtga gtgatgattt acttccagat atggcaatac tagacccaga
    11821 gcttgtaaaa actgtaccaa attttataac agcagataca gggatggatg tattgacaca
    11881 tgctatagaa gcttacgtat ctacaaattc taatgacttt tcagatgcac tagctgaaaa
    11941 agctataaag ttagtattta aatacttaat aaaatcatat aaagatggaa atgacataga
    12001 agctagagaa aaaatgcaca atgcatcttg tttagcaggt atggcattta accaagcatc
    12061 acttggcata aatcattcta ttgcacatgt attaggtgga aaattccata taccacatgg
    12121 aagaacaaac tctatattac ttcctcatgt aatagaatat aattcatcaa tagtaggata
    12181 tactaacaca acttactctg atacagctaa aaaatatgca caaatagcag aattagtagg
    12241 acttgggagt gctaatataa gaatatctgt tagaaattta gtaaatgaaa taaagaaact
    12301 acaaaaagaa atgaatatgc caactaaatt gacacaatgc aaattaagtt tagaagatat
    12361 aactaatgaa gaaagagaaa tagcaaaact tgctataaaa gatacttgta cattaactaa
    12421 tcctaaggta ccaactgaag atgatataat aaacatatta aagaacatta aataactaca
    12481 ttttattaca tgtaaatata atattataca aatagggaaa atgtttttaa aaatataaat
    12541 tatatattga caaatataaa acataaaact ataatgaaag tatcacaaag gcgtgatact
    12601 ttagtagaaa gcaatggagc ttcttaggaa tattaatatt attcttatgg agctcctttt
    12661 attttaatca aatagctttt taataaacta tattcaaaga aagcagggaa taaatttgac
    12721 tgaagaatct aagcaaagag ttattcaaga atatgttcct ggaaaacagg ttacattagc
    12781 acatatcata gctaacccta atgaagacat atataagaag ttaggattag tacttgataa
    12841 aaaagatgca ataggaatac ttacaataac accaagtgaa gcgtcaataa tagcagcaga
    12901 tgttgctaca aaggcttcaa atgtatcttt aggttttata gatagattta gtggttcagt
    12961 agtaatatca ggtgatgtaa gttctgtaga atcagcgtta aatgatgttt tagaagtctt
    13021 aggaaatatg ttaaacttct catctacaaa aatcacaagg acataataat acaatgaaga
    13081 atataatatt tatgggaaag acaggtagtg gtaaaactac cttatgtcaa aaactagacc
    13141 agttagaatt aaagtataaa aaaactcaat cagtggaact ttataataat gcaatagaca
    13201 ctcctggtga gtatatggaa aatagaaacc tatataatgc cttaataaca acatcagcag
    13261 atgctaaaat tatagcaata gtgtatgatg ccacacaaga agaaaattat atagcaccag
    13321 gttttgccag tatgttttgc aaagacgtaa taggaattat aactaaaata aataaagcta
    13381 ctgaaaacga agtcaatata gcttatgaaa gactatcact agcaggagca agtcaaatct
    13441 ttaaaataga cacagttgat aatattggac ttgaaaaatt atttaaatat ctagaaaaat
    13501 ataaaaatat agatgaagtt taaggggaaa tattttttta ttcaaaaata ttattaaagt
    13561 atgataaaat aaaaaaatgt ataaactatt ttaagaagat ttaatcttta agcgaggtag
    13621 gaacatgggg aaaaaaatac tattggttga tgatgaacca ctgttaagga tggatacaaa
    13681 agatatatta gaaagtcatg gctatgaaat aataggcgaa gcaagtgatg gatttgaagc
    13741 tgttgaaatg tgtaaaaaac acaaacctga tttagttata atggatatag agatgccaat
    13801 acttgatggt ataaaggcag gcaaaataat atgtaaagaa aatctagctg gtggagtact
    13861 tttattaact tcatttgaag ataaagaata cgtagaaaag gctaaaagta taggtgctta
    13921 tggatattta gtaaaaacag caagtgaaaa atcacttatc ccaaccatag aaatgtgttt
    13981 aaataaggta aatgaatttg aaaaaatgaa aaaagattta gaaaaagtaa attctaaatt
    14041 gaatgaaaga aaattagtag aaagagcaaa aggtatactt ataagagagt ttaagatttc
    14101 tgaggatgaa gcatacacta gaataagaaa attaagtatg gataaaagaa ctacaatgat
    14161 ggaaattgcc aaaatgatta taataggata cgatgactaa tacgataaaa aaaatatcaa
    14221 ctgcacaaac atacttaaat aataacgaaa ttgaaaaaat tatagaagta tcaaaatcct
    14281 tagatttaat ggcttctttt tatgaagctg atgtttttat agatgtacta agtaaatttg
    14341 atgatgaagc aattgttgtg gcacatggta gacctaaaga aaagtcaatg tactgtgaaa
    14401 atgttatagg taaaaaggct ttaattgaaa atgaaccagg agttataaag tgcttaaaaa
    14461 caggagaaag agtaagagat attaaagctt taacacagga atataaactg gtcaaacaaa
    14521 atattcagcc aataacacta gatgacaaag ttttagcagt actaatagtt gaaaaagata
    14581 taagtagtga agttaagaat gagtttaatg ctagtgaaga cgaagaaaat aaaaatttac
    14641 atcagtttat aaaacttatt ggaaataatg actttttagt tgataattta aattcagcca
    14701 tattaatatt tgataaaaat ggaaaattaa aaattaaaaa tcgtattgca actgagatat
    14761 acaaaaatct tgggtttgga tatgatatac aagatatgca ttacaatgat ttagatatag
    14821 aaaccaacac ctttgaaaat atattaatgg atgaaaatta tgatgagaca aatgaagttt
    14881 caataggtaa tatgtttttt aaaataaaga ccatatacat caaagatgat gaatttaagg
    14941 tttgcaaaat agtacaagat ataagtgatt taaagagaaa agaagaagaa ttagttttga
    15001 aaacagtggc tataagagaa gctcatcata gagtaaaaaa taatcttcat acagtaatat
    15061 ctataataaa aaaacaaagt agattatctc aaaatgatga agtaaagcag tgtttagata
    15121 acataataaa tagggtattt gcaatacttt cgactcatta tttactatct aaagaagttg
    15181 ataataatat atctatacga gaaggtatca atttattagt gtcaaatatt caaggtggct
    15241 atttatttag taaggatata gatatacgta taactggtga agattttaaa attagtggag
    15301 aaaaagcaac agcaatactt ttggttataa atgaaatact acaaaattgt tatgaccatg
    15361 cattttcgga tagagaacat ggtactatac aaatattaat aaataaagat aacgactata
    15421 gaaatattgc tattatagat gatggaattg gatttgatag taataatata aataaaaata
    15481 gcttagggac atatataata gatagttata taacacagat gttaaaagga aatatagaga
    15541 gaaaaagtag tgagaatggt acagaagtat taattactat acctacacaa attaatattt
    15601 aaataataac tcatctacaa agtagtagtt ttaattgagc aaagaggctt aaggttatta
    15661 atagattaag ttaattgaat gtatttataa aaattataag tatatattca atttaacagg
    15721 tatttattat aactttaagc ctctttgctt gtttaagaca tacttaaatt ttaggaggtg
    15781 agaaaatgag agaagagtta ttaagtgttg gtattgacat tggaacaagt actactcagt
    15841 taattttttc taaattaata gtagaaaata ctgaatcaaa tttttcggta cctagaataa
    15901 gtatagtaga caaagaaatt atttataaaa gcaaagttta tttcacccct cttatttcaa
    15961 ataatgaaat aaatggtcaa caaataaaag atatagttga aaatgaatat aaaaaagcaa
    16021 atatatctaa agaagatata catacaggag cagtaataat aactggtgaa acagctagaa
    16081 aagaaaatgc aaatgatgta cttcatactt tgagtggatt tgctggggac ttcgttgttg
    16141 caacagcagg acctgattta gaaagtataa tatcaggaaa aggagctgga gctcatattt
    16201 attcaaaaga acattcaact acaattgtaa atatagacat aggtggggga actagtaaca
    16261 tagcctcatt taaaagggga gaagtaaccg atactggatg tttggatata ggtggaaggc
    16321 ttgtaaagat agataaaata agtaaaaaaa taacttatat atcacctaaa atagataaaa
    16381 tcataaaaga taataattta aatcttcaag taggcacaat ggctactgta gaaaatacaa
    16441 agccaatagt ggatataatg gttgacttat taatggaaag cataggatta aagaaacaga
    16501 cacctttgtt tgattttata ataaccaata aatcaataag tatagatgaa actattaaaa
    16561 atgtttcatt ctctggtgga gtagctgatt atatttacta tgatggagaa ataaaagatt
    16621 attttgaata tggtgacttg ggaattttac ttgggcaagc aataaaaaat tgtgaatacc
    16681 ttaaaaaagt aaatgtagtt aaatctatgg aaacaataag agccacagtg gttggagcag
    16741 gttctcatac tactgaagta agtggaagta caataactta cactagcgaa aagtttccac
    16801 ttaagaactt gccagtttta aaattatcaa ttgatgaaga aacaggtact tcaaaacaaa
    16861 tcagtgaagc tataaaaaat aaacttaatt ggtttaaact agaaaatgat ttacagaaag
    16921 ttgctatagc catgatagga aagaaaaatc caaccttttt agatatacaa gagtatgcta
    16981 aagggtttgt agatggaatg caacaaatca tagaaaatga tttacctttt atagtaattg
    17041 ttgaaaatga tatggcaaaa gtgttaggtc aagcaatata tgcattatta aattatgaaa
    17101 aagaaattgt ttgtatagac agtgtcaagg ttgaaaatgg agactatatc gacattggaa
    17161 aacctatagt tgaaggtaaa gttttacctg tggtaataaa aacattagtt tttaattaat
    17221 agaaggaggt aagtaaatga ttttaaatac aaaattattt ggacgtactt atcagtttaa
    17281 aggcttatat gatgtaatgg ctaaagctaa tgaagaaaaa tcaggagata aattagcagg
    17341 tcttgcagca gaatcagctg aagaaagaat agcagcaaaa gttgttttat cacacataaa
    17401 attggaggat ataagaaata atcctgcagt ggcatatgaa gaagatgaag taacaagaat
    17461 aatacaagat gctgtaaatg aaaaagttta tgaagaaata aaaaattgga cagtctctga
    17521 acttagagaa tggctattgg attcaaatac tacaagtctt gatataagaa gaatatcaag
    17581 aggattaact tctgaaatga tagcagcagt tgcaaaatta atgtcaaata tggacttagt
    17641 ttatgcagct aaaaagataa aggttactgc tcactgtaat acaactatag gagaacaagg
    17701 aacattatca gcaagacttc aacctaatca tccaacagac gacccagatg gaatacttgc
    17761 atcacttctt gaaggtttaa cttttggtat aggagatgca gtacttggat taaatccagt
    17821 tgatgactct gttgagagtg ttactaaagt attaaaaaga tttgaagaag taaaacaaaa
    17881 atatcaaata ccaactcaaa catgtgtatt ggcacacgtt actacacaaa tggaagcaat
    17941 aagaaatggt gctcctgcag atttaatatt ccaatctata gcaggttctg aaaaaggaaa
    18001 tgaagcattt ggatttaacg gcgacactat agaagaagct agacagttag ctttaaaaca
    18061 cggtacagct acaggaccta acgttatgta ttttgaaact ggacaaggtt cagaattatc
    18121 ttcagaagca catcatggaa tagaccaagt tactatggaa gctagatgct atggatttgc
    18181 taaaaagtat gaaccattct tagtaaatac agttgttggg tttataggac ctgagtactt
    18241 atatgatgct agagaagttg taagagcagg acttgaagac cactttatgg gtaaactaca
    18301 tggcttacca atgggtgttg atgtttgtta cactaaccat atgaaggctg accaaaatga
    18361 tatggaaaac ttagccatac tattaacaac agcaggatgt acgtatttta tgggaatacc
    18421 tcatggagat gatgttatgc ttaactatca aacaacagga taccatgaaa cagcatcact
    18481 tagagaaatg tttggactaa cagcaataaa agaatttgat gcttggatgg aaaagatggg
    18541 attctctaaa gatggtaagt taacagagtt ggcgggagac gcatctgtat tattaggata
    18601 ggaggtattt aatatgaatg agaaggattt aaaagcattg gtagaacaat tagttggaca
    18661 aatggttgga gaattagata ctaatgttgt gtctgagact gttaaaaagg caactgaagt
    18721 tgtagtagac aacaatgctt atatagatga tataacagaa gttgatataa gaaagcaatt
    18781 actagtaaaa aatcctaagg atgcagaagc ttatttagat atgaaagcaa aaacacctgc
    18841 aagattaggt ataggaagag ctggtactag atataaaaca gaaacagttt taagatttag
    18901 agcagaccat gctgctgcac aagatgctgt attctcttat gtagatgaag aatttataaa
    18961 aggaaataat atgtttgcag tggaaacttt atgtaaagat aaagatgaat acttaacaag
    19021 accagatttg ggaagaaaat tttctccaga aactataaat aatataaaat ctaaatttgg
    19081 tacaaatcaa aaggttttaa tattagttgg agatgggctt agctcagctg caatagaggc
    19141 aaatttaaaa gactgtgtgc cagctataaa acagggtcta aaaatgtatg gtatagattc
    19201 aagtgaaatt ttatttgtta aacattgtag agttggtgct atggaccact taggtgaaga
    19261 attaggttgt gaagttatat gtatgttggt tggagaaaga ccaggattag ttactgctga
    19321 atcaatgtca gcatatatag cttataagcc atatatagga atggcagaag caaaaagaac
    19381 agttatatca aatattcaca aaggtggaac aactgcagtt gaagcaggtg ctcatatagc
    19441 tgaacttata aaaactatgt tagataaaaa agcttcagga atagacctta aataaagtcg
    19501 agggagtgta gaatatgaaa aatgatgtaa ttcgtcctaa tatactagga attaaaataa
    19561 tttcaaatat aagtccagaa atggcacaaa aactagaatt aaaatcacat cacaaaagct
    19621 taggtttaat aactgcagac tgtgatgatg ttacgtatac agctcttgac gaagcaacta
    19681 aagcttcaga agttgatgtt gtatatgcaa aatcaatgta tgcaggtgct gcaaatgctt
    19741 caacaaaact tgctggtgaa gtattaggaa taatagcagg tccaagccca gcagaagtaa
    19801 gaagtggtct aaatgcagta gttgattttc tagagtatgg agcaactttt ataagtgcaa
    19861 atgatgatga ttcaatagca tactatgctc actgcgtatc aagaacaggt acataccttt
    19921 cagaggtagc aggaataaga gaaggtgaag cattagctta tttagtagca ccaccccttg
    19981 aagcaatgta tgcactagat gcagcaatga aagctgcaga tgttaagatg tgtgaattat
    20041 ttgcacctcc aactgaaaca aactttggtg gagcattact tacaggttct caatcggctt
    20101 gtaaagcagc atgtgatgca tttgcagaag cagtaaaatc agttgcagac aatccaacag
    20161 gattttaagg atagttagat ggatgctata ggcttaatag aagtaatagg atatgttgct
    20221 gcaatagaag cttctgatgc ttgtttaaaa tctgcaaatg ttaatattgt aagagttgat
    20281 aaggttgggg caggtattgt tactttaaca atatgtggag atgtcggtgc tgtaaaagct
    20341 gctttagaag caggtgaaat agcagcttcc agagttggta cattaagaac atcacatatt
    20401 ataccaagaa tccataatga agtaacaaat gctttattca aaactaaaga acctaaagtc
    20461 tgtgaagttt cagaagataa agaaaaaaac tttgagatta cattggaaat aactgataat
    20521 gtatcgaaaa atttatcaga aaaagaaaat gtaattttag atgtcaatga aaatagcgga
    20581 aatactgaaa atttatatag tgatatagat aaaacaaaca aaaaaattga aacagttgat
    20641 gatagtttaa cagaagctaa tgaggaaaaa atagaaaaca ctaatgataa agaagtattg
    20701 gaacaagtta aaatagaaaa ttccgatttt gatagagatg acctatcaaa gaacagtgta
    20761 aaaaaactta aagctatggc taagaaatta gattcttcaa taacttataa agatttaaat
    20821 gttcttaaaa aagaagaatt aataaactta gttaaaaagc ttagcagaag ggatagatag
    20881 ttatgacact tttagataaa gatttagtat ctatacaaga agtcagaact cttgtaagaa
    20941 gatctaaagt ggctcaagag aaactttcta aaatgagtca agagcaaata gataaaatag
    21001 taaaatctgt tgtagatgca gcatttaata atgctactaa attagctaaa atggcaaatg
    21061 aagaaactgg atttggaaaa tgggaagata aagtaattaa aaatactttt gcatctatgg
    21121 gagtttatga aactttaaag aacacaaaaa ctattggaat aattggtgaa gataaagaag
    21181 ccaatacgat agatatagct acaccagttg gagttgttgc aggtcttata ccttcaacaa
    21241 acccaacatc aacagtaata tacaaaacta taatatctct aaaagcagga aatactatag
    21301 ttttctctcc acatccaaat gcaaaaaact gcatacttga aacagttaat ataataagtg
    21361 aggctgctat aaaggctgga gctccagagg attcaatatt atgtataact aatccaagta
    21421 tagttggaac caatgaattg atgaaacata aagatacaaa cttaatacta gcaactggag
    21481 gagaagcaat ggttagagct gcttactctt caggaacacc agctattgga gttggaccag
    21541 gaaatggacc agcatttata gataaatcag caaatgttaa attagcaatc aaaagaataa
    21601 tagattctaa aacttttgat aatggtgtta tatgtgcatc agaacaatct atagtaatag
    21661 aaaaatctat ggaagaaact gttttaaaag agcttaaaaa tcaaggtgca tatgttttaa
    21721 atgaagagga aagtgaaaga ttagcaaaat tcatattaag agctaatggt actatgaatc
    21781 cacaaatagt tggtaaaagt gttgaggtaa tagcaaattt agcagactta acaaatgtac
    21841 ctaaaaatac aaaagttcta gttgcaagag aaaataaagt tggtcacaat gtagcctatt
    21901 caagagaaaa acttacacca atactagcgt tctatgttga agaaaatgta gaagctatta
    21961 tgaacagatg cagagaaata ttgttaaatg aaggtgcagg tcatacattc tcaatgcatg
    22021 taaatgatga agaattggta aaaagatttg cccttaatat gccagtatca agaatacttg
    22081 tgaatactcc ttcagcactt ggaggaatag gtgcatcaac aaaccttgta ccagcactaa
    22141 cacttggttg tggtgcaata ggtggaagtt caacttcaaa caatatagga ccacttgatt
    22201 taataaatgt taaaagagta gcttatggaa tcaaagaaat agaagaactt ggaagagata
    22261 aatctcaagt tgaaaaatca atgtttgact caatggataa agaagaatta ataaatcttc
    22321 ttgttcaaaa actagtcaaa gaactagcat aactaaaata aacaatgaaa cttatagcta
    22381 tcactataaa tttctaaaaa tataaactat aaaaaactat aaaattaaat ttttggagga
    22441 taagattatg gcaagtgcaa acgcattagg aatgatagaa actaaaggat tagtaggagc
    22501 aatagaagca gcagatgcaa tggttaaagc tgcaaatgta caattagtag gaaaagagca
    22561 agtaggtgga ggattagtta ctgtaatggt aagaggagat gttggagctg ttaaagctgc
    22621 tacagatgca ggagctgctg ctgccgagag agttggagaa ctaatatcag ttcatgttat
    22681 accaagacca cactttgaag tagatgctat attaccaaag gtatcagctg agtaatataa
    22741 gaataattat aaaatttaaa ttttgattga aaaagaggct atctcaaaaa tgagtcttac
    22801 taataaactc aatgtatttt gaggtagtct tttttataca tctaatagga gatgtgataa
    22861 aatgggtgtt ttaacagaaa gcgaagtaaa aagaaaaatt ggaaaaaaca aaaataatat
    22921 aactgaattt tatatagaaa aaggtcaaat aataactcct tctgcaaaat cttatttagc
    22981 tgagagaagt attgagctta aatatgttga taaactttca gatgtaaaca atgaacctaa
    23041 agaagttgta aaagaagtag ttaaagagaa aaaatataga tatactactg tatttggcgc
    23101 taaattggat gaaaaaccag aacatatgac tcaattaaat ggaaatcttt tagtttttaa
    23161 agaccataaa agaataatat tgagaggaaa aatagattct cttgaatcag aaatactaaa
    23221 ggtacagata ctttgtcaga aactagatat gccaaagctt gttaaggaat tgcaagaagt
    23281 attagacttt gtaagaaata taatgagatg tgaagtttta gatgaaaagc taggggactt
    23341 taaactttta ggattaactc ctcaagaact tagagaacaa tctcactatc ctaaaaaata
    23401 ctttggtata ggacatgagt tcccaagtta tgaaatggga gaagtagtag tagctataaa
    23461 tagtataaga agtaatacac gagaggttga acttgcagcc tatgaagcat ttaagggtga
    23521 gtatggaaat gttcacagag aagatttaat aaaggcactt aatagattat cgtcagtatt
    23581 ttggataatg atatataagg ttagaactaa taagtataag tagttggagg acataatgga
    23641 gaatctatta aatgaaatag tggaagaagt aataactaga gttaaaaaag aagcatttat
    23701 agaagttgaa gcatcaggaa gacacgttca cttaagtaga gaagatgtcg ataaattatt
    23761 tggagaagga tatactctta caaaactaaa agacctatct caaccaggtc aatatgcatg
    23821 taaggaaaga gttacaataa ctggtcctaa aggaagtata aaaaatgtag ttgtacttgg
    23881 accatgtaga aatgaaactc aggtagaaat atctttaaca gatggttcaa ctcttggact
    23941 aaaagctcct ataaaacaaa gtggagactt agaaggtact ttaagtatta aaatatcaac
    24001 acaatatggt gaagttgaac ttgataaggg gttaatggtt gctaaaagac atatacacat
    24061 gactcctaaa gatgctgaaa aattcaatgt atgtgataaa gagatagttg aagctaaggt
    24121 gatgggtcaa agacctttaa catttgatga tgtagtaata agagtgagtg acagttttaa
    24181 aacttatatg catatagact atgatgaagc caatgcatgt ggttattcaa aaggaactgt
    24241 tgctaaaata ataaagaaag cgtaaattta acctactata taaattacct ctagggagga
    24301 tttaatatga attatgataa ccttgtagat ttaataacgg aagaaatcta taaaaaaata
    24361 aatagtaatg aaataaaaat atctaataaa cctaaagctg tgattgtatt tgaacaagat
    24421 aacaataaat ttaacttatt aaaagatgaa tttgaaatag tagaatttga taaaagtata
    24481 agggaatgtg aaatagtgat agtttcaaga ctttgtatga gggggctatc gaatatagca
    24541 cttggaaatt caacaagtga tgaagaaaga tttatactaa aaatgattat gaagggcaaa
    24601 gaagtatatg tcctagatga aggaattgaa tacaaaaaat ataaggatac tgcaccaaaa
    24661 gcattatata agaaatttat gtcatttgaa gatgaaatat gtaaatttgg tgtagaaatt
    24721 ataaaagact taaatgttat aactaaaaat aagttaaata taaagaaaga actagaaagt
    24781 actagaggtt ctaaaaaaga agatacaaaa gttttagata aagatgtttt aaatttaatc
    24841 agtgtagaaa gtgtaaaaat agataatgaa tttagtttag atttaaggaa taaaaaactt
    24901 atatcggaag ctgacttaag aaaaccaact ataaatggag ttaaaaacat attagttaat
    24961 aaaaaaagta taataacacc attagctgta gattttatga gaatacacca tctcaaacta
    25021 aagaaagtgt aaggaggtaa ttttatggat ataggaaaag ttgtaggtaa tgtttgggct
    25081 acaagaaaag atgaaaaatt atgtggccaa aaacttttag ttgtaaaaat tttaaaaact
    25141 aaagacacat acaaggaagg cttcatggtt gcagccgata atgcaggagc aggaaatgga
    25201 gacttagttc ttatatccaa aggttcctca gctagagagt cgattgaaaa atctcatgtt
    25261 ccggtagatg caactatagt tggagtagtc gattcgtttg aggtgtttga tgaataaaag
    25321 tataggagct atagagttta aaagcattgc taaaggtata gaagtatcca atgaaatgat
    25381 aaagaaatct tcagttgatg tattgtactt aaaaagtatt tgcccaggta aatttctaat
    25441 aatagtaggt ggagaaactt cttatataaa tgaatgtgta gattatggaa taaaacttgg
    25501 agaaggatat attgtagata acttcgtaat aaatgcaatt tcacaagaaa tattagatgg
    25561 atttaaaaat aagtatcaaa agctagatag tatagtctct ataggcgttg ttgaaagtag
    25621 taaagtatgc gctggaataa aaatgcttga taagacttta aaatctggcg acttagtatt
    25681 agtaaaactt caattatctt ttgctatagg tggcaaatta gtatatatag tagcaggaga
    25741 tttaagtagt ttagaatatg cattaaaaga aagtgaaaat gtagtaagag aaaaagaagt
    25801 aatatataag actgtaatac catcagtaga cagtcaaata ataaaaagtc taataaaata
    25861 atggggggaa ttatgagtat aaacgaaatt ataatctatg taatggtagt cttcatggta
    25921 cttggagcta tagataaatg tataggtaac aaatttggtc ttggagaaca atttgaagaa
    25981 ggtataatgg caatggggtc acttgcagtt gcaatggttg gtgttatatg tttagcacca
    26041 gttcttgctg atgtattaag accaattgta gtaccagtat ttaatatact tggagctgac
    26101 ccagctatgt ttgctggaag tttattagct aatgatatgg gtggtgcacc acttgcactt
    26161 gaacttgcga aagaccctaa tgctgggtta tttggtggat taatagtagg ggctatgatg
    26221 ggacctacaa tagtatttat aataccagtt gcgcttggaa taattgaaaa agaagaccaa
    26281 aaattcttag caacaggaat acttgcaggt ataataacaa tacctattgg agcattcgtt
    26341 ggtggattag ttgcaggatt cgaggtaatg atggttctta gaaacttagt gccaataata
    26401 atatttgcag tagttatagc acttggatta ttaaaattcg aaaatgctat gataaaagga
    26461 ttcacatact ttggaaaagg tgtagtaata gttataactt taggacttgc tgctgccata
    26521 gttgaagctt taacaggaat agttgtaata cctggaatga aaccaatcag tgaaggtata
    26581 gaaatagttg gagatatagc aatagtttta gcaggagcat tcccattagt gtttgttata
    26641 acaaaggtat ttaataaacc attaatggct ttaggaaaag ttcttggaat gaatgatgta
    26701 tcagcagcag gccttgttgc aagtttagct aactgtatac caatgtttgg tatgatgaaa
    26761 gatatggaca atagaggaaa aataataaat gtagcattct ctgtatcagc agcattcgta
    26821 tttggagacc acttaggatt tacggcagga tttaattcta atatgataac accaatgata
    26881 gttgctaaat tagttggtgg tataacagca gtattgttag ctatggttat cgcaaataag
    26941 acactaaaga aggagaatgt ataagatgga tatatcaaat atagataaaa atttaattga
    27001 aacattagta agacaaataa tagaagaaaa aataagtgga actaaagaca cagtagattt
    27061 tgttagaaat aaagacatta gtggaataac ttctataaag ttaccaactg taaaagttag
    27121 tgaatctgat agattagata cagggaatcc aagtgatgta gtttacacaa aagatttatt
    27181 tacattagag gaaagcccaa gattaggttg tggtatgatg gaaatgaaag aaacaacttt
    27241 tgattggact ctaaactatg atgaaataga ttatgtaata gatggaactt tagatataat
    27301 aatagatgga agaaaggttt ctgcttcttc aggtgaatta atatttatac caaaaggaag
    27361 taagatacaa ttttctgtac ctgattatgc tagatttata tatgtaacat atccggcaga
    27421 ttgggcatct caaaattaat aaaaatcaag ttaagttaat aataatcaaa taaataattt
    27481 aaaatacaaa ctcttaaata agcacacata tttaaaaaag ctatgaatta aaattcatag
    27541 ctttttttat aaagaatgtt atattttaga cgtatttttt ctatatttac tgggagacat
    27601 attatatttt ttattaaata atctaataaa atgctctaca tttggataac caatactatt
    27661 ttactgataa tcttttcctt atcactaatc ttacatttta aaatattatt tttactcgta
    27721 atattatcat aagaatttgt ttcttattta aaactaatta gaattataaa gtttattgcc
    27781 atgttattaa taaaataaat ccagttaaat cgagtgctag ttaaagtaat aagaaacttt
    27841 tacaatggtt tcctttatcg attgaaataa aagttaatat ggtataatat ctaaagagag
    27901 aatcttatca attagaatat gcatagaaac aagtggctta aaaggagacg ttatatggaa
    27961 gagatagtaa agaaggaaca agcaagtatg aatgatattt ttttgtatct taaagctaaa
    28021 tcaaactcat tatataaatt tgtaatatta tataatgagt ttatcaataa acctaaagat
    28081 tatggaactg gggaacttat aaacatggtt gaagtacata tgctaacagc gattgaagaa
    28141 aatccaggaa taagtccaac tcagttagct aaaatatgga acagaactaa aggtgcaata
    28201 tctcaaacta tatctaaatt ggagaaaaag ggttatataa ctaaagaaaa gaaagaagga
    28261 aatgcaaaaa ctatattact atatccaacc acatcaggag tagagttaag taaggcacat
    28321 aaactatatg acaccataga tgttacaaga acatttgaat acttaatcaa ggagtgtaca
    28381 ttagaggaga tagatagttt ttataaagta attgatttgt ttattaattt attagaagaa
    28441 tctccgcagg aaaataatga ttctgaaaaa gtgtagctga gattgaagtt gaataaagag
    28501 aaatagatat tatagaagta gtacttaagt acacattata taaaaatata ataggtatag
    28561 gattaaaaag tttagtggtt taaagtttaa ccactaaact tttttaatgt ctataatcta
    28621 ctattattta atttactaaa aataaaaaaa ctcattatat taagataaaa atagaaaaat
    28681 aactagaaaa atactataat atatcagctt aatacagaaa aaagttaaaa aatttgagaa
    28741 aaataaaaat gaaaacgttt tatattgaca tagagaaaaa gtagtgatac catttaaata
    28801 tagtttagta gctaaactat atttaaatta taataactat tttaggggga tgttatgaat
    28861 ttaaaacaat taagtgaaaa atacgaagaa tatgtaattc aaatgagaag agaatttcat
    28921 aagtatccag aattatcttt taaagaaata agaacaaccc aaagaataag ggaagaatta
    28981 caaaaaatag gggtcccttt tgtatctatt gaaccaaata tcgtaatagc tactatacaa
    29041 ggcaaaaatg aaggtaagac aattgcaatt agaggagata tagatgcgct tccaatgcaa
    29101 gaagattcag atgttgaata caaatcagaa tatgatggaa taatgcattc ttgtggacat
    29161 gatgctcatg gagctatgtt actaggactt gcacatatgc taaatgatat aagaaaagat
    29221 ttaaaaggta gagtattatt agtttttcaa gcagctgaag aagttggtgg tggacacaag
    29281 gagataatac agtactttaa ggaaaatgga ggaccagata gattaatagc tactcatgtt
    29341 tggtccgata ttgaagctgg taaaatttct gttgaaccag gacctcgtat ggctggtggg
    29401 tctggttgga gaatagacat aacaggtaga ggaggtcatg gttctagacc agatcaaagc
    29461 atagatccta taaagccagc ttgtgatata gttttaaaag tatcttctat accagttaat
    29521 catataagtg tactagaaca atgtgttgta catgcatgtg caatacatgg aggaactaca
    29581 ataggaaatg ttattccaaa caatgcagag gtaataggtg gatatagata ttttactgaa
    29641 gaatcaggca aaaaagtgtt tgacattata aagcaaatga gtaatggtgt tggacaagtt
    29701 tatggagtgg atgtgaaggt tactcatact ggaggcatag gacctgttat caatgatgaa
    29761 gaagcagtta agatggctaa agaaatagtt tctaatatag atggattgga gttagattct
    29821 tatgagccaa tatgtgcatc agattgttat ggtgaaatat taaaagagta ttctggcttt
    29881 tattgttatc taggggtagg taacaaagaa aaaggaataa tatatgcaca acaccatcct
    29941 aagtacaata tagatgaaga tacattaaag ttaggttgcg aatttatggc taaatatgca
    30001 gttgaatttt taaataaaaa taataactaa aataaatcga attttataaa tgggggggat
    30061 gaaaatgcaa ggtgcattaa aggaaaataa gaaaaaaagt ggtggaggat ttttaggatg
    30121 gattgaaaaa gttgggaata aaatgccaca tcctctagca ttatttacat atattacatt
    30181 gatagtagta gcattatctg caatagcaag ctttttaggt ttttcagcaa caagtcctgc
    30241 tacaggaaag ttaataaaag ttatgaactt aataagtgca aaaggtttag tactatttat
    30301 gcaagagttt gttaagaact tccaaaactt ccctgtgctt ggagtagttt tagttatggc
    30361 agttgccaca ggagtttgtg aaaagacagg atttttttca actgccataa aaatgagttt
    30421 atcaaaagtt aaggggaatg cggttgtatt tataatagct tttataggag tatttgctaa
    30481 tcaagctggt gatgctgctt ttgtattagt accaactctt gcaggagcaa tattttatgg
    30541 attaaataga aatccattag ctggtatatt ctgtggattt gcatcagttg gtggtggatt
    30601 tgcaacagct gtaattcctg ggggatggga cgttacgcta acgccaataa ctgtatcagc
    30661 tgctcaaact attcaacctg catttgatat gacattatta gctagttatt atgcactatt
    30721 tgtatctgcg tttatagtag ctacagtatc aacaatagta acggttaaat ttatagaacc
    30781 taaattaggt aagtatactg gtaaaccaga aggtatagat gataatcaag gttttgaggt
    30841 cacaaaagaa caagcaaaag cagcaaagtt agcaggtttt acagttttag cttatgtagc
    30901 gttattaatt gctttgtgta taccagctaa tagtttttta agaagtccag aaggttcttt
    30961 aatatttgga gcaccactta tgtcttgctt acagtttttt atagtaatac tattcttctt
    31021 gccagggatt gtgtatggaa tgagggttgg taaaatcaag actgtaaaag acttaaatga
    31081 tatattatgt caatcaatgg cagcaatggc accgtttatc gtacttgcaa tagttatagg
    31141 tcaattctta acgctattct cagtgtctaa tttagcacag gtactagcta taaaaggtgg
    31201 agcattactc aactcattgc cactaccacc acaagctata atactgctat tcttagtact
    31261 agtagcgttt ataaatatat ttgttataag cggaagtaca aaatggatga tatttggacc
    31321 agtatttgtt ccaatgttaa tgcaattaaa catacatcca gcatttactc agtttgtata
    31381 tagattagga gattctgtaa ccaatcattt atcaccatta aatgcattct ttataatact
    31441 tttagcaaca gtccaaaaat acgataaaaa tgcaggtatg ggaactatat tctcagctat
    31501 gataccttac actataggtt actttgtagt acttgcagtt ttagtagtag tttggatgac
    31561 aataggtata ccagtaggaa taggtggaca agtttggtta taaaacatat ttaataattt
    31621 tgggaggaaa gaaaatggaa acaactgaaa taagatacaa ttttgatgaa gtaatagata
    31681 gaagtggaac aaactgtctt aaatatgatc ttaagagtca atttatgcca gaatctccag
    31741 aagatgcact accactatgg gtagcagata tggattttgc atgtgcccct gagataatta
    31801 atgcaatgca tgaaagaata gacagaaaaa tatttggata tagctctcaa caaactgatg
    31861 attattatga agctgtatgt ggatggttta agagaagatt tgattggaaa atagaaaaag
    31921 agaatatatt ctttagccca ggggttgtgc ctgcgttagg atttttcaca caaatattaa
    31981 cacaaaaggg tgatggtatc ataatagaaa agcctgtata ctatcctttt gaagataaaa
    32041 taactaataa tgaaagaaaa gtagttaata gtcctttaaa gtttgaagat ggtcattatt
    32101 ctatggatta tgatggattt gaagaattag ctaaagatga aaataataag gtgtttatat
    32161 tatgtagtcc tcataatcca gttggtagag tatggaaaaa agaagagctt agaaaaatag
    32221 tagacatatg taagaaatat gatttgtgga taatatctga tgaaatacat tgtgatatta
    32281 ttcgtaaagg tgaaaagcat ataccattag aagtagcatg tcctgattat aaagatagaa
    32341 taataacttg tacagctcca agtaagagtt ttaacttagc tggtatgcaa ttatcaaata
    32401 tagtaatcaa taataaggaa ttacaaaaaa aatggatgct tgaaacagat tctaaattag
    32461 ctatattcct acctaatcca ttcgcaatag ttgctactaa agttgcttat aatgattgtg
    32521 aagattggat gaatcaagta aatgagtata tagatggtaa tattaaatat gtagaagatt
    32581 ttgttaatga gtatatgcct aaagtaaaga taataaaatc tcaaggaact tacttagttt
    32641 ggttagactt tagagggtat ggattagatg caaaacagct tgaatatgta atgcttaaca
    32701 aggcgaaggt attgctagat gaaggataca tattcggaga agaaggagca ggatttgaaa
    32761 gaataaatgt tgcttcacct agaacaatta tagaagagtg tatgaataga ataaaatgtg
    32821 catttgaagg attataatag taatatctaa ataatatatt tgtgtatttt aaaaaaagac
    32881 tatgctaaaa aaatatttca aagcatagtc ttttaaagtt ttatgatgag tttaaaaaat
    32941 ttcaaaacgt tactattcac ttatatgttt atattagaaa taattccaca atatactcat
    33001 tttctaaagt tgcactttta tacaccttgc ttcaccaata tcatgtgtaa ccaaaatagt
    33061 agacttattc tcattcttaa taatactata aacatcatca caaactaata atctagtctg
    33121 ataatcaaga gctgaaaaag gttcatctaa aagtagaata tctggattta cagaaagtgt
    33181 tctaataagc gcaactcttt gtctcatacc tccagataat tcttttggat acatacttct
    33241 aaaatcccat aatccataag tctttaaaag gctttcaact ctatctaaag attttttatc
    33301 ttttttgcct tgaatttcca atccaatagt tatattatcc attatatttc tccattcaag
    33361 caaattatct ttttgaaaca tatatccaat atttccagta atctttatat caccactagt
    33421 cggttttaaa agattagtaa gaatatttaa tattgtagat ttaccacttc cagaaggacc
    33481 aagcaaagtt aatatttctc cttctttcaa gttaaaattg acatccttta atacttcaag
    33541 ctcgccttcc ttagtgtaga agttcatatt tatattttta acttctacta tgttgtcatt
    33601 cattatgcca ccccctataa cttttagctc gtatatatta tgttattaac aatatgacct
    33661 atttgtacca tttttcataa atataatata aatattttgt ttatttacgt attttcttag
    33721 taacttgtac gtataaatta tagataaata aattataagg taggggataa atttgagtaa
    33781 cataataacg aatttaatag agtcaatatt tactaatcca ataactatat tgtttttact
    33841 tgcaataact gtgtattctg tttttaaaat aatagaaaat aacagagtat attcatttgt
    33901 aagttcaaaa ttagacgaaa tcaatagaga ctataagaca agtgagtttt ataaaaaggt
    33961 aagggatgac tactatacat atagtaaaga aaatccttat gcagacgtaa atataacttc
    34021 atttatagag gaagttgtat ctgatttaaa gcataataat ttgccattgt tagaaaaaat
    34081 tagaagtata aaaaattcat cttcaataag tatattactt ggggttttag gtacgtttgt
    34141 tggtctttct acaatgcttt tatgtgttga tactaaagac attataaatt cacttccttc
    34201 aactattagt agtatgcaaa ctgcatttac aactagtata tttggagttg tattttctct
    34261 aattataggt tactttacta agataaaaga ttgtgaacat gttttgatac aaataatgtt
    34321 aaaatctgaa aatttactaa catctgaaat aactcatttt aagtcagaaa gaatggattt
    34381 aaaagtagaa gaggtaaaaa atacaataaa acaaataagt aagtctatag aagctattga
    34441 aaaatttgat aaaatatcta aagatttaaa tgactttaat gatgaattta tcagtggtat
    34501 agaagcttta aaaagccttt tagaaggttc tcaaagttct attaagacat ttgaccagag
    34561 cgtaagaaaa ttagataaac agtttaatat tttaaatata aaatttgtaa agctttttga
    34621 taaatatgat aatcaagata atataaataa agagatttta tttgatataa aagaatcttc
    34681 aaaaaatata tacaatgcca ctgaaagcca attcaaaatt agagattata taaaaaatat
    34741 aaatgcagga tttgctctat atgaaagaag tgctcaagat ttattaacta aattaatgac
    34801 ccatgaaaat aaaatatctc aaaatcaaaa aatcctttta gatgaaaagt ttaccttaga
    34861 tgactcaata aaaaatctct caagtattat tgaaaacttt tctaatgacc tacaagttaa
    34921 actggatatg atgtttgaaa attctttaga tattcaagat aagttagatg ttatgtttaa
    34981 taactctttt atgaatgatg aagttcctct tgatagtgaa gaattattta aggatgatgt
    35041 taataatgta tttaatcctt ttagtgaaga aatttatgag atagaggata aagaaataaa
    35101 ggtcataggt gaggatgagt taaatgaata ataaatatag aagaactgtt aacagagaat
    35161 ttgaaaagag tagcttttgg ccaacattta cagatttatt atctactgta ttgatggttg
    35221 tgattcttat cttatttagc tcagaaagta tttcaggttc tgttgaacaa gatttagcta
    35281 agaatgtcaa tgcttctgtt gaagaaactt ttaaaaaaag tggaatacct gtgaaggtag
    35341 ataaatctaa tgggcaagta acttttggtg aaaaaaccat gtttgatgta gatagtgatg
    35401 ttttaaaacc agaggctaaa gaaatgctaa aaatgtttgt tccaaagtac atagagacta
    35461 tttataaaga ttatggtgac tatatatcca aaatagttat agaaggtcat acagatgatg
    35521 tgggaagtta tatatacaac ttagatttat cgcaaagaag agcatatagc gttgctaaat
    35581 ttatagtggg agatgaaata ggtgactata aatacaaaga taaagtgact aagcatatta
    35641 ttgcaatagg aaggtcaaaa gctgaactca tcaaaaatgg tgacaatagc gtgaatagag
    35701 atgcatctag aagagtagaa ctaaaatacg aaataaatat taatcaaaat aaataattaa
    35761 atttttataa aaaaaaagaa ggcagttggt gtgagcttta agccttcttt aaggaaaaag
    35821 tttatttatt tttgttgata cttaacatat tatagttttt agaagcagtt tgcaatatat
    35881 taaacgtaaa tggtcgttta aaatgcataa ctggatacta ctgatgtaaa atatttcatt
    35941 ttatataata taaaaattat acagtgtcaa ttttctatat tattgtacta taatctatta
    36001 tttaaaatat tatgtaaaaa aatatcataa aaacgcatat catgttataa ttactagagt
    36061 attatgaata tggaggcgta gtttgtgata gaaataagta taaaaaataa aaaaaattct
    36121 aaaattaaaa ctttgatact tttattgata gtatctatat cgatttattt aactggttgt
    36181 actacatcag ataatggaaa taatcaatca aataataatg attctttgtc tagtagtata
    36241 tcaagtgata agaatgtaaa aattcatttt attgacactg gaaatagtga tgcaatattg
    36301 attcaagatg gtaaaacttt tacattgata gatgggggag ataatgatga tgagggatta
    36361 atggtagatt acctaaacaa tcaaggtgta aaagatatta aatatcttat agctacccat
    36421 tctcatgcag accatttagg tggacttgat tctgttgtca aaaactttaa tatagaaaat
    36481 gtttttgtat cgaatggttc agcagaaaca aagagttata gggactttat aaatgcttta
    36541 gcaaataagg gtttatcccc aagtgtaccg cttgaaaata ataagttcta tttagaagat
    36601 tcttattttg aagttctaaa tacaaatggg ggagatacta ctaatgaaca atctctagtc
    36661 cttgtatata ctaatgggaa tgataaagtt ttatttacag gtgatgctga agaaggtacc
    36721 gaaaaagaaa tactacctaa gcttgagaaa gtagaccttt taaaagtagc tcatcatggt
    36781 tctcgtagta gttcatctca agagttttta gataaagtaa atcctgaata tgcggttctt
    36841 ttagtaggca agggtaattc atatggtcat ccacatcagg agacaatgaa taaattaaaa
    36901 aaaatgggag taaaagtgca tagaagtgat gagtgttcag atataatatt tgaatcaaca
    36961 ggtgatggag tatttacaag ttgtaaagat ggaagttata ataaaggcgt tagagaagat
    37021 ggaaactctg gaaaatcaaa cagtaataca agtaaaaatg attcttttaa aaataaacaa
    37081 aatacatcca attcagaaga aatagtgtat tttactccaa aaggtaagag ctatcactct
    37141 acaaaaaatt gtagtgggct ttcaagaagt aaaaaaatat tatcaggcac aattgcagaa
    37201 agtaagaaaa atgacccatg tgatatatgt tatggaaaat aacaaaaaaa caaccaattt
    37261 atctataaag cttctgaact ttaaatcatt caaaaaataa aataaatgca taaaaaaata
    37321 agctataatc aatagataac acattttatc tatacgaata gcttattttt ttaagtattt
    37381 tttaatagct atttaataac tctaaataca ccagttacaa tacctacaat ttcaacttct
    37441 gagtcattga gcataattgg ttccataaaa tcattttctg gctgaagtct tattaaattt
    37501 ccttctttaa aaaacctctt aactgtagca gattcaccat ttataagtgc aactactatc
    37561 tgagaattta aggctgtatt ttttttgtct actacaacgt aatcttcatc taaaattcct
    37621 gcattaatca tactttcgcc ttttactctt aatacaaaat tgttactgcc ctttactaaa
    37681 ctggcaggga atggaatgta ttcctctatg ttttgttgag ctaaaatggg ttctccagct
    37741 gttatttgac ctactaaagg aagctctatt atttcttgat tagctccaga aacatcattt
    37801 actttactac gttctaaaac ttcaatagct cttggtttag tagggtcctt tcttatgtat
    37861 cccagttttt caagtttatt tagatgagag tgcacagttg aagtagatct taaccctaca
    37921 gcagtacata tttctcttac agcaggtgga taacctttta atatgatttg agactttata
    37981 aattccaata tcaagacttg cttttcagtt agatctaaat acataacatc actcatttcc
    38041 aaacatattt tgtttttatt tccatacact ttatattttt aattataaca taatccattt
    38101 atatctgcaa acatttgttc ctgattttta atcgtcctca atccattcaa aattcttgac
    38161 tatatcacgt tttacatttt tcttatgagc tgcataaagc tgagtagttg tgacattatc
    38221 atggtcaagt aagttttgaa catcatatat agaaaatcct gtttggatta gagaagttgc
    38281 agccgttgct cttaatttat ggggactata tccattgtct ctagtagtat caagtggaat
    38341 agatgtatat ttttttacca gtgttcttat agcctttgct gtaattctct tattttgaag
    38401 agacaaaaat aaagcatctt tttcttcatc atttaatagt tcatctcttg ttctttcgtt
    38461 ttgcaaataa tcttttatta catgttcaca agtatgattt ataggcatta aaacttcttt
    38521 cccacgtttt ctatatattt taaattcacc tcttgaaaaa ttaaaagagg agatattgag
    38581 ttctctaagc tcatttaatc taagcccgta tgtaacaaat aatgctagta tagctttgtc
    38641 acgtaattta gtttttctcc aatatacctt ttctttctct gtaagccctt cacctgtttc
    38701 tactgattca agcatcttag caacttcatc tatctcaagg cgcttaatag catctggctg
    38761 aggtttagga agttttattg gattaaatcc atcagttata ttattatcta tctgagagtt
    38821 tctgtataag aatttaaata gagtagagat ggatgatttt tttcttgcta aagctctatt
    38881 gttattttca aaaatcaatg tgtttttttc tgtatttttg taatatctac tgcaataatc
    38941 acctaagaat aaatttatat ctcttgattt tattgtatta aaatcatctt ctgtaatatc
    39001 ttttacacaa tctgcatttg ttaattcttt ggtttcaatc aaatatgaac aaaaaaaatt
    39061 aatatcttct aaataagcaa gtcgtgtaga aactgcaaca gaacctttta aatatataaa
    39121 ataatccttc ataaatacag gaagtttatt ttccaaaagt agacattttt ctatgagttc
    39181 attttctttg ataacaatat tatcaggttt atctgattta ttatgtactt ttataatttt
    39241 cttatcatta ttcaaaatta aacctcctaa aactaaaata taaatctttt atattatttt
    39301 ttgatattta taccaagtga gtataaatat ttaatttaat cattttttac atttttaaga
    39361 gattagcagt actttagatg aaattatcac taactattcc ctaaatccac atttaaagac
    39421 tagttgaatt taattactct ttttttattt ctcaatatat ttatagaaat attttaaaat
    39481 atattaatat ttttatatgt ttctaacgaa accaaatatt agtaaaatat gtatttattt
    39541 aactaaagtt tttaaatggg ctgactaagc ttaaaatata ggatattatg agagttacta
    39601 ttgaaaaaat aaaccctatt gccataaaga aacttataaa tatgttatac ttaactatta
    39661 aactggatat attcaagtta tcaaatccaa ataagtatgt aattgaactt attacaaaaa
    39721 taactataac tataaagctc agaccattta agctattttt taaatcagca ctactaagtg
    39781 acatatgtgt agatatagaa tacattaaaa acataaatat aaaatacttc aatgaatata
    39841 cactaggtgt taacaacatt attcttataa aattggaaat atcacctaaa ataatgtgta
    39901 taaaaccatt tatatttaag ttattaatca tacttacata taactttaaa tctatatttt
    39961 gagtcacttt catataacta tctggcagta atatcttaaa aattaaaata atcattattg
    40021 ttccacctat aataggtgca attcctataa agaaatttcc tatactttga taaagattat
    40081 cttttttata gctatgactt acatatccta gtataccatc atttttactt tctattggtc
    40141 tgaaaaactt aactgaattt attttatgca tgaaaattaa acacattatc aaatgactca
    40201 attcatgaac aaatgttcct atagctccag ttacaataat tccagttttt ccaaaagatg
    40261 aaaatataaa tttattattt agattttctg taatgctaaa aatcaatcca aatacaataa
    40321 atattcctat gaaacaaaaa atatttatta cacttatttt taaaatttcg attatataaa
    40381 tcataagtta agtcctcatg taaaagtatt taactactct acttcatatc cattacagct
    40441 taaaatttta caagcatttt ctatatcttt ttcttttact aagatatagt ctgtatcata
    40501 cgtagaaatt gcaaatatgc ttattttgtt gtctgctaac aaactactta acttagataa
    40561 aattcctaca agtgaaaagt ctaaaggacc tagtatctta agtattctcc actccttttc
    40621 tgacttgaca tcagaaggaa tattattatt taaacataca acacttaatt catcatcagt
    40681 tctagttata gagtaaaact tctctgtatc tatccatgtt ggtattttac tgtcattatt
    40741 taatctacat actgcatact cttctaccaa taattttaat ttcataatgt atatttcctc
    40801 caatcttatt tgtttactta agattataca ttaaaagtta cataaaataa aacatataaa
    40861 gtaaaaaagg ttcactatag tgtcctattt ctatagccaa cctttaaaac ttaattaaat
    40921 tctaataaag agatatatta tctaggttca attataagtt taatggctgt tttcttatca
    40981 ccttcgattt ctatatcagt aaatgcggga atgcaaacta aatccattcc actaggtgca
    41041 acaaaacctc ttgctattgc aattgatttt atcgcttgat ttagagctcc agctcctata
    41101 gcttgtattt ctgcaacgcc tcgttctctt agtactccag ccaaggctcc agctacagaa
    41161 ttaggattag attttgatga aacttttagt acctccattt caacatctcc ttgttaattt
    41221 gttaaagtat ccattaccta aagtactaaa tcataattgc catttactaa ttacaatcat
    41281 catttaaagt atacttttat aaaaatatac ttctataatc gttttaagaa aacctttatt
    41341 ttttttaacc attttattat gaaaaaacta caaatttctt tatattctat aagcattttc
    41401 caatatttct aaatttttta tatctttgag ctataatttc ctctttatcc atatctttgt
    41461 aatgatttaa tctttctaaa atataagctt ttatttcttt tgaaacagct tctacatctt
    41521 tttgtgctcc tccaagaggt tcttttataa tcttatctat tatttttaaa tcatataaat
    41581 cattacttgt aagcttcata acatcacaag cttctttagc tttagatgaa tctttaaata
    41641 gaatactaga aagcccttct ggagaaatta cagaataaac tgaatgttct aacatacata
    41701 catcatttcc tactccgata cctaaagctc ctccactacc accttcacca attacaaaag
    41761 tgattactgg aacagaaagt ttactcattt caagtaagtt tcttgcaata gcttctcctt
    41821 gtcctctttc ttctgcttct agaccacaaa aagctcctga tgtatcaata aacgttatta
    41881 taggtctatt aaatttttca gcttgtttca taagtcttaa tgcttttctg tatccttctg
    41941 gatgaggcat tccaaaattt ctttttatat tttcttttgt atctcttcct ttttggtgtc
    42001 caactatagt aacattaaac tttcctatct gaccaattcc tccaaccata gaagggtcat
    42061 ctttaaaaag cctatctcca tgaagttcta aaaaattaga acaaatatgt tctatgtatt
    42121 ccaatgtcgt aggtctcttt atatctctac ttagtgttac cttttcatat gctgatagat
    42181 gtgaaaaagc atcttcctta agcttttcca atttctcatt aagtgaattt attttatcac
    42241 ttaaatctat attatttgcc ttagaaatag ttattaattg tttaatatca ttttctaaga
    42301 tttttatttt ttcactatta ttttcaatca aaacagttcc tcctttatgc cctatttctt
    42361 gtgcatagca agaatttgat ataatacttc cttcattttt cttctatcta ctatcatgtc
    42421 aataaaacct ttttcaagta aaaactcaga agtttgaaat ccttcaggaa gtttttgatt
    42481 tattgtttgc tctattactc ttggacctgc aaaacctatc aacgtatttg gctcagaaat
    42541 tataatatca ccaagcatag caaaactagc agttactcct ccagtagtag ggtcagttag
    42601 aactgatata tatggcaatg atttttcttc aagcttagaa agtgcttgag aagtctttgc
    42661 catctgcata agagatacca taccttcttg cattctagct cctcctgaag cagaacaaat
    42721 aattataggt aaattatttt cagcagcata ctctattgaa taagttattt tttccccaac
    42781 aatagaaccc atacttccca tcataaaatc aggattcatt acacaaataa ctgttttaat
    42841 tccatttatt cttccataac ctgtgacaac agcttctgac tcttttgttt tttccttata
    42901 agagtctact ttttctttgt atttaggaaa atttagtgga ttttgaaatt ctacatcaga
    42961 attaaactcc ataaaagttc ctttatcaat caataaattt attctttttc ttgctcttaa
    43021 gccataatgt cttgaacatt ttggacatac aaatgaattt tcttctatgt cctttctaaa
    43081 tacatgacta tcacaacctt tgcaataggt ccaaaattta tcatctacac tattcttttt
    43141 aaagttgtca tctaaagaaa tcgtaacata cttagattct tttgatgata aaaatttttt
    43201 tatcataatc tatttactcc ttataatgta gcaaattctt tcttcataaa gacatcttct
    43261 ataaatttgg tatgatgagt atcttctcta aactcctcac ttgttacaag tgccttttga
    43321 aattctacat ttgtattaat accttctaca ataatttcgt ctagagctct atatattcta
    43381 cttatacatt cttctctagt ttcagcccaa catattaact tacctatcat agaatcatat
    43441 aaaggtggta tagtatatcc tgcatataca aaagtatcaa atctaacacc aaaacctcca
    43501 ggtaaattta atgattctat cttacctggt gatggagcaa aattctttga tgaatcttct
    43561 gcatttattc tacattcaat agcatgacct ctaaaagtaa tatcttcttg tttaaaagga
    43621 attttatccc cattagctat agatatttga agttttataa ggtcaagatt tgttaccatc
    43681 tctgtaactg gatgttcaac ttgtattctt gtattcatct ctataaaata aaagttttta
    43741 tctttgtcaa ctataaactc aatagtacct gcaccgatat aacctactcc ttttactata
    43801 tctactgcaa ttttatgaag tttttgtctt tcttcatctg aaaggtatgg acttaaagat
    43861 tcttctatta ctttttgatt tcgcctttgc atagaacaat ctctatcacc taaatgtatt
    43921 gcatttgaat gtttatctcc aaatacttgt acttctatat gtctaggatt ttctataaac
    43981 ttttccatat ataaatcact attagaaaat gctgctagag cttctgaact tgccatatca
    44041 aaatttgaaa aaagttcttc ttcttttcta acgattctca taccttttcc accgcctcca
    44101 cttgaggctt ttatcataac aggatatcca atttctcttg caacttctaa agcttcttcc
    44161 ttagttttca aaacagattc tgaaccagga acaacaggga tattcaattc catcatagtt
    44221 tctcttgctc tagatttatc tcccatcaaa atcatttgtt ctcttgttgg acctataaaa
    44281 ataatattat tatcttcaca ttgctttgca aattcaggat tctctgataa aaatccaaag
    44341 cctggatgaa tagcatcaca ctttaattta agagcaagat agattatatt ttctatatta
    44401 ttataactct tacttatatt atttggtcct atacaaatag attcatcagc tatatatcta
    44461 tgaaaacaat ctttatctat ttcagaatag atagcaacag tttttatacc tagttcttta
    44521 catgttctga tgattctaac tgctatatcg cctctatttg caactagtat tttttttatc
    44581 aacttaaata cctcctacta caatggtttt atcttaaata aaggttgatt atattctact
    44641 agttcttcat tactaactaa tacttcaatt atttcacctt taatttcact tgttatctca
    44701 ttcataagct tcattgcttc taatatacat aaagtgtcgc cttcttcaac tacatcgcca
    44761 actttaacaa agctatctgc atctggactt ggagaatcat agaatgttcc catcaaagga
    44821 gctactacta ctgatagatt ctcattagat gtgacaggtg tatcgtttac aactggcttt
    44881 tctaaagaaa gatccactac tgattcttgt tgtacactta aaacaggtga acttgtagat
    44941 tgagcttttt tagatacttc taatcttaaa tcgctacttt caagttttac atattctaag
    45001 ttagttgagt ctatggcctt taataattcc ttaatttcat tgatgttcat tttgttaccc
    45061 ccttgtatta ttacctggtg ctaatattat atcacaaaaa acaaatttat aaaagaaaaa
    45121 gtgctgacta gagaatcaac acatcaatat atcttttaat tttaaattaa caaccagtaa
    45181 cttatatttg ttttaatttt ccattattaa tataaattat aagtataaaa tgaataaaat
    45241 tcaatatttt ttgcaaaata caagagaata caaattaata cctcgggaat ttttaagaca
    45301 aataccaata ttatgcaatt tagacttcgc tttctttcaa attagtatca ttttctttat
    45361 ttttacatag gatgtacttt aatttagcta tcaaaacatt gctatatagg ttaaaagtta
    45421 ttagaattgc aggaattata aagtaaactc tagcacctat aaaaccaaaa actactgtaa
    45481 taagtattaa tcttttattt aaagtaaaaa aaggtatatt aaaaatactt ttgtcggatg
    45541 tttctggagt ataagaatat ataactccaa aaatcaaagt aagcatacaa agtggaagta
    45601 gtgtataact tgaaattatt cccaaaaatc ctatactttc aaaatatttg ctagcactat
    45661 ttgtataaac aaacatgtat ccatttaaat atgcgcatat acatgatata atgccaaaag
    45721 ttccccctaa ggattgagtg taccaattaa aaaatttaga ttccatatac ctcacctcct
    45781 aaaactgtat atataatgat atgcatttaa atagtaaaat atatctttat atgtttctga
    45841 ataaaatttt gttaatttca ttaatttatg tttaagaaat ttgaagtata gtgtagtata
    45901 tattaatgta gatgaagttt tatagtactt atttcatagt gcttaatcaa gttatcttat
    45961 tatggattca aaagttgttt gtagggtttt atattttgtt gagctgaaaa atttattata
    46021 aatgaaggga tgttttcgct ttggtagata cattagaatt tggtcttaaa attttatttt
    46081 ttatattatc aataatttgg atgggtaaaa taatgatttt aagaactgat aagcaaatag
    46141 taatcaatcc tttgcttatt ggtatatctg cagtccttgt gatgttgcat acctcacaga
    46201 gtaacattga attttttgga ttagatgtcc aatatataag aatagttttg tatataatat
    46261 attcactgat aattttaata ggaatatggg ctactaacag aagaaatgga attttttaga
    46321 taatctattt ctataaaatt taaaggttgc tagtaacaaa tcactaatat tagcgttctg
    46381 ttactaacaa cctttatttt gattatacac ttaaattgaa aatagaatga ttgaataagt
    46441 tgacagatta ttttacattg acagtaatta gaacttcttg agatgtattt aaatcatttt
    46501 tgtcgcttag tataactttt accactgctt gacctgtttt attaccttta attatcatat
    46561 cttcacatga aagtacactc ttatcactta cagatacaat aaaatttaaa tcttttggaa
    46621 ggttatcagt aacttcccag tatttataat aactatcaat tttcttcgta attatttttc
    46681 tcaaatcaat actttcacct tttgctatat caacattatg atatttagag tccagtttat
    46741 actgattatc ttttgtatca ataaaattta aatcgcaatt tacatccaca ccattatgag
    46801 aaagagaatt tactacatcg tcatcaatca aataattatt ggcaagattt attgaatcca
    46861 tatcttttag acttaaagct tccttaggaa cctcttttat attattattc caaaaaataa
    46921 aattgtctac attttcaaga tatgatatac cttttaaatt tgaaatactc tcaccagttg
    46981 cataaaattc tccatctaaa gcctttatat tgcttatagt catctcatct ggatttatat
    47041 atctttttac aactgctctt aaatttgcat caggaaaaat atctttaagt tgattttcgc
    47101 tcaaaacctt atcatttgaa tttattggac ttaaagctgc tgcagaaata ataaatggta
    47161 ttaaattagc taaattcata gtaccctccc acataaattt tttattataa taatttaatt
    47221 tctatgagag ggttctgttt ccttgttata tatacctact ttcgtacact ttattaatat
    47281 aaattaaaat aaatttctac tattaaactt ataaacatat tactagttac gttttttagc
    47341 ttcacatcta aatattcgca taccttgtga cataaatttg tcttcatact ctgttgtaac
    47401 attattttca tactcactat ttcctaaatc aagagaaata ttctttaata gccaattatt
    47461 tgcagcaatt tcatttaaac taaactcgaa taatttttca ttatctgttt taaagtgaat
    47521 ttcgccatca tcttccaaaa ccctattgta catttctaaa aatccagaat gagtgagtct
    47581 tcttttactc catctatttt taggccatgg gtcacagaaa tttatataaa ttctcgataa
    47641 ttctttagct tcaaagtaat ccaaaatatt gcttacatct ccccataaaa atagtatatt
    47701 attcaaatta gaagcatctg ctttttcaac agcctttaaa agaacttctt ccttaagttc
    47761 catggcaata taatttatgt cagggttctg cttagctaaa gttgttataa acttaccttt
    47821 tccagtccca aattcaacat gtattggatt atcatttcta aactttaaat tccacttgcc
    47881 ttttaatttg tctatatcgt ctcttaaaac atattttgta taacttaaaa gcttttcatc
    47941 tgcacctttt tttcgtcttc ttctcacaat aattctcctt acatataaaa aattagtaaa
    48001 atacattttt attatacatt atctcaccaa aaaataaaaa gaactctctt aaaatagaaa
    48061 tttatttcta taaagagagt tctaaactta ctaaaaactt aatcttagtg gcaccctgaa
    48121 caaccagagc atcctcctcc accttgatct ttcatatttt caggaataac tctaaatcca
    48181 aatcctgtat cttctattat tatatctcca tactgactat attcatcaga gctcattaca
    48241 aattgtaatt ctccaacttc ataagttaag tcatcttctt ttttctcatc taaagctaat
    48301 ccaaaagaag gacctccaca accaacacct gcaaagtata ctcttatatt attaggttta
    48361 tcttgattgt cttttaagat actttttaaa gtatcaatag ctgtttctgg taaagtaatt
    48421 ttcatcaaat cattcccttt caaatatttt attaaaacaa tatctattat atacccatac
    48481 aaggtacata atcaattagt ttttgcatat tttactaaaa cttctaccta atattaccta
    48541 aggctttaaa atattttata taatatttta ttaccttaaa taaatacc
//
LOCUS       DAMKNB010000023        48169 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.024, whole genome shotgun sequence.
ACCESSION   DAMKNB010000023 DAMKNB010000000
VERSION     DAMKNB010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 48169)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 48169)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..48169
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.024"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            complement(73..684)
                     /locus_tag="PC494_001490"
     CDS             complement(73..684)
                     /locus_tag="PC494_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HDF3911994.1"
                     /translation="MKMVKKLILSTIMALVLVLTIGCSNAEEKVKSNFEANLAALEMY
                     KYDEKGISDALTEAEYKQIQTYNSKDKVSMIAQLTPLYGKENAEKIYETIVKLIQGVE
                     KTVTVESSSKDKITLKVVSKALDTSKVMSEANTLVKSYVTDEKNYDKKEKEVQDDMTK
                     MIIDLYNKKPTKEVTTMITYTKKDGKWQPPSNIQKLCEGIYTI"
     gene            complement(776..1765)
                     /locus_tag="PC494_001491"
     CDS             complement(776..1765)
                     /locus_tag="PC494_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine cyclodeaminase family protein"
                     /protein_id="HDF3911995.1"
                     /translation="MLLLKKDDIKKVFTMRDAIEADKEAFRIYCEGKSVNPLRTNISV
                     PSQDASMLFMPGYVEELGCGGIKIVSVFPKNAQKGKPVIPATVLLLDGETGEVSAVLD
                     GTYVTQIRTGAASGAAIDVLAKKDSKIGALIGLGGQGEPQLEAMIEARNLDEVRVFSR
                     NKESREKFAEEMNLKLSKYNTKIVAVESSDEAIDNADVIVLATPSKQPVLNGNLVKKG
                     ALISAVGSYMPDMQELCPNCLTRASKIFFESTDAVLSESGDILIPLKEGKISKDDFSG
                     DLGNVINGTIPGREDDDEIIVFKTVGIGVQDVVTAKRIYDKAKENGIGIDWKW"
     gene            complement(1832..2695)
                     /locus_tag="PC494_001492"
     CDS             complement(1832..2695)
                     /locus_tag="PC494_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3298 and DUF4163 domain-containing protein"
                     /protein_id="HDF3911996.1"
                     /translation="MKFFKVDTKAKVLRYVFVLTLTIMAVLAIKHDYKYNNLRKDASI
                     NLNSNKEAVTVMSNQSLPKGNTNSKQTLSVSTIGSKTIVKNDEYLESTINMPVITNSN
                     KIVERSTNDKIKNDIFEFYNKSYKEAKQYLKDNPDEKNKFVANVDFELKKNTDSALSI
                     KVRYYTYSGGAHGFYQDIAYNVDMRTGKFLELMDLFKDNTKYKEVIDEEIKRQIAELE
                     KKDEENIGIYNFKGIKENQNFYLQDENLVVYFDLYDITPYAAGIPEFSINKALISSML
                     KPEYVDLFDLK"
     gene            complement(2801..3397)
                     /locus_tag="PC494_001493"
     CDS             complement(2801..3397)
                     /locus_tag="PC494_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein CheB"
                     /protein_id="HDF3911997.1"
                     /translation="MERFNNMVIAIGASVGGTEAILEIIKDLPKSTPGIVVVQHMPAI
                     FTYMYAQRLDKQCIMNVREAKNNDRVEQGNVLIAPGGYQMKLCTDKQGYYVTCEKGER
                     ISGHCPSVDVLFDSVAEVAGKNSIGIILTGMGYDGASGLLKMKENGSFTIGQDENSCI
                     VYGMPMVAFDRGSVMLQLPLGEISNCLIRHINILKQKD"
     gene            complement(3437..4240)
                     /locus_tag="PC494_001494"
     CDS             complement(3437..4240)
                     /locus_tag="PC494_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-glutamate O-methyltransferase CheR"
                     /protein_id="HDF3911998.1"
                     /translation="MIKLTDEEFIVLVNHVKKEYGIDLSKKRALIEGRLYNTMIEKKL
                     SSFSQYMNLLFKDKTGNEAINLINRLSTNHTFFMREPQHFEFIQNSILPFWEENNKIR
                     NINIWSAGCSSGEEAYSIAMTLDDYFGYNKELWNIKIIATDISTNSLEKAKRGIYIES
                     NVNNVPELWKKKYFIDNKDGTFKICDKIRKSVIFKPFNLMNDFSYQHFDLIFCRNVMI
                     YFDLKTREELINKFYNATKKDSFLFVGHAEVINRSSTKYKYVKPAIYKR"
     gene            complement(4276..4716)
                     /locus_tag="PC494_001495"
     CDS             complement(4276..4716)
                     /locus_tag="PC494_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein CheW"
                     /protein_id="HDF3911999.1"
                     /translation="MAKDEIIKQVLTFYVNDVIYGIELENVIETIRFQSITYVPCLPT
                     YISGVINLRGRIIPVINMHIKYNLPKADYNERTCIIITKVDEYQVGIIVDKVVDVIHI
                     ENLNLLETTNSNNTNINKDIKEIAKVEDNSILILDIRKFLINSI"
     gene            complement(4729..6831)
                     /locus_tag="PC494_001496"
     CDS             complement(4729..6831)
                     /locus_tag="PC494_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein CheA"
                     /protein_id="HDF3912000.1"
                     /translation="MRQMLDMFIFETSLLLEQLDEIMIQIEKEKVFTHNNINETFRIM
                     HTIKGSASMMGLDNISALAHSVEDLFYAIREGKIEVLDNDLLFDLVFQSLDFIRRDID
                     ELQSRGCISSDYSNFIEGIEEYVSTLELSSSMKSKDNANLESTDEKEVIDSNFEYKEG
                     SDVVKIIFEQGCMMENVRAFMLVFELRDYCEFIDFYPKDVETNAESTEYIKSYGFYIQ
                     FVAKEDKAIVYKTIEDNLYVKEYINISKKEIEMKNTSNNDAVENKLKDNNKVSKSYQN
                     NYTEDEIQEDVLNEKTDMEKDSLSEENEHLPISKQSIMSVNLEKLDLLQNIVGEIVIM
                     ESMVVNSVNSTGVDIDNFNKATRQLHKLTDELQDIVMSMRMIQIAGVFQKMHRIVRDM
                     NKKLDKNVELITIGAETEVDKSVIDNLAEPFMHLIRNAMDHAIEPIEERIAKGKEEVG
                     KIVLSAENLGGEAVISISDDGRGIMRDKILAKAKEQGLLKHQSNEYTDDEVNSLIMTP
                     GFSTKESITEFSGRGVGMDIVRKSIEKVGGSIEVKSKQDEGTTFTIKIPLTLSIVEGM
                     KFKVGDSLFTLPISSIRRTFKLTDLNQIITEGNKTELITIYGACIPIIRLHKIYNIQT
                     KVTNLMNGNMIIIENEHKAVCIFVDEIIGNQQVVVKPFPVYFNRFNIKNKGLSGCTIL
                     GDGSISLIIDADSIIEIY"
     gene            complement(6950..8653)
                     /locus_tag="PC494_001497"
     CDS             complement(6950..8653)
                     /locus_tag="PC494_001497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing protein"
                     /protein_id="HDF3912001.1"
                     /translation="MKREVKLSKLAIVLLIIIVLAVLAGIFSSISSYKAFEKVEKSIN
                     DMNNLRTQSQYIKDTTREISDVLRRYVFTGEKKNKDIYEKELYGKTRESALNKLEKIG
                     LTKSESNKILEAKEISDSLVPTEQSAIKAVESNDKSKAQSIIFGSDYINSQEKMDSLI
                     NEFQEDIVTRSNSKIVEVKKELQSLILRTIFILSLLIILTIIEYTVIKLKIVIPINKV
                     EKHFSRIASGDLRTSIDVEESKSEIGLLVSSVKKMQSMLLNYIDLIDSTLTSIAKGDL
                     RVEIDQEFIGDFKSIKISLESIINSFNGDFSEINLSAEQVASASEQVAAGAQALSQGA
                     TEQASSVEELASTINEISDGIKKCADSASLACEVSDQSASQVGFGSRCMDDMMTSMGE
                     ISEKSSEISKIIKTIDEIAFQTNILALNAAVEAARAGQYGRGFAVVADEVRSLAGKSA
                     KAAQNTAILIEEAIKTVENGVRIAKETANALDLVVNGVEKTTNYINGISSAVHSQEVA
                     ITQILSGIEQISIVVQMNSATAEESAAASEEMSAQAQILKELVEKFHLKESEVRESSW
                     V"
     gene            complement(8679..9638)
                     /locus_tag="PC494_001498"
     CDS             complement(8679..9638)
                     /locus_tag="PC494_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HDF3912002.1"
                     /translation="MKNKQQGTILVVDDSVLMCDLIDKTLTKDNFKVKKAFNAIEAKE
                     FIEEFIPDIILLDIILPDNSGFEFCKEVKSNARTADIPIIFITSKNTDTDIVKGFGVG
                     AIDYMVKPFSMTELKARVIAHLEVKKSQDKLKKINNELESSLEKLNRLVVRDYLTGLY
                     NRRHIINQLMEQRRINKYSETSISLILGDIDDFKVINDTYGHEAGDFVLTVISSIIKK
                     NCRQIDTVSRWGGEEFLIMLTNTPIEGAKILSERIRKEIKEFDFNYKEHKIKCTITLG
                     VVEVNSNISLEENISLADKAMYEGKNLGKDCSVVSTMKGLKKI"
     gene            complement(9774..10292)
                     /locus_tag="PC494_001499"
     CDS             complement(9774..10292)
                     /locus_tag="PC494_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-binding chemotaxis protein CheW"
                     /protein_id="HDF3912003.1"
                     /translation="MRFPDDPYLDYGLIDEGIKYLKFKVDEQDFGVELEKIIEITGNQ
                     EIIFIPELPTYSKGIINLRGKIIPIIDMRLRLKKDELMTTNCMYIVVTEIKDLVVGFV
                     VDRVDDIVSLEKSKISPPPRVTIEYSDYFVSGVGELEGKIITLLDLEKLLTDKDEVLI
                     DELINGFDCTIM"
     gene            complement(10335..10820)
                     /locus_tag="PC494_001500"
     CDS             complement(10335..10820)
                     /locus_tag="PC494_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein CheD"
                     /protein_id="HDF3912004.1"
                     /translation="MNREIVVNIADMKIAYRPNVLVTYALGSCVGVCLIDKVAGIGGM
                     LHVMLPYSKDAINIENKCKFADTGINELIKSMENIGANRIYIKAKIAGGAQMFLGSSN
                     SVIASIGHRNVEAVKKTLLGLNIPILAEDTGMNYGRTIRFYTETGELLVDSINKGKKK
                     L"
     gene            complement(10817..11434)
                     /locus_tag="PC494_001501"
     CDS             complement(10817..11434)
                     /locus_tag="PC494_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein CheC"
                     /protein_id="HDF3912005.1"
                     /translation="MINYLELDDVHIDALREIGNIGSGNAITALASMINSNVEVLIPM
                     VKILEYNEATNLLGGPENKVVCILLDMKGDINGMFMFLLDESITQLMLSSLFNKEEAF
                     LDEIEAIEISAIKEIGNIMASSYVNAIASMLNMTISVSIPDICIDMVGAVLNVPMIRF
                     SDVGDKVLFIENKFKMSDNYFTSHILMIPEMSSLKEILVRLGLEV"
     gene            complement(11499..11861)
                     /locus_tag="PC494_001502"
     CDS             complement(11499..11861)
                     /locus_tag="PC494_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HDF3912006.1"
                     /translation="MENKILIVDDAIFMRMIIKEALSKSGYNNLIEANDGEEACNIFK
                     YEKPDLMLLDITMPKKDGLEVLREIKKLDSSAKVVMCSAIGQENMIVEAIKLGALDFI
                     VKPFKTETLVKVVDNALK"
     gene            complement(12605..13102)
                     /locus_tag="PC494_001503"
     CDS             complement(12605..13102)
                     /locus_tag="PC494_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="effector binding domain-containing protein"
                     /protein_id="HDF3912007.1"
                     /translation="MNYEIVEINEKIVIGISKETTNKDGQAVNDIGELWKKFMGKGIY
                     NAIKGKKNDKTIGLYTDYQGDFTSPYSFVACCEVNSNSDKEKNLEELNTNNTVGESII
                     SKVIPAGKYAKFVIVGGQKEVGDFWFEFWQMDFDRTYISDFEEYQCNTFDTKKQEIHI
                     YIGIK"
     gene            complement(13277..14188)
                     /locus_tag="PC494_001504"
     CDS             complement(13277..14188)
                     /locus_tag="PC494_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YafY family transcriptional regulator"
                     /protein_id="HDF3912008.1"
                     /translation="MKINRLTEIIVILLNKKLVTAKELADRFEVSTRTIYRDIETLSM
                     SGVPVYMTKGKGGGISLIEEYSIDKAILSKKDKESLIVALKTLQATKYPEINSVVNKI
                     GSIFGEQNFSNWIEIDFTEWGSNFNEDDKFTKIKEAILRRNTINFNYVNSLSSQTNRT
                     VEPLKLMYKSKTWYLYGFCKLKDDFRIFRISRIRNLSIKDEVFSRKIIEEVCLNDSKV
                     IKENTITLKLRFKEKMLFRVFDDFNKDLITKNEDDTYDVITEFPIGEWIYGYILSFGD
                     NVEVLEPKDVRDNVITRLRELSKIYSL"
     gene            15112..15963
                     /locus_tag="PC494_001505"
     CDS             15112..15963
                     /locus_tag="PC494_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3100 domain-containing protein"
                     /protein_id="HDF3912009.1"
                     /translation="MEINKKHFIQVFLTCLILVVICEFIGQRTIAIGKASIVLFPMLY
                     AVIIGLIITPDLLGKKIKALKKVVGEKEINIAGEVVGIALVMLGIKYGTTVGPNIDKI
                     IQAGPAFIAQEFGHILAPIVALPLALMFGMKREAVGATASISREPSLGVISEKYGINS
                     PEGSGVLGTYLMGTVLGTIYFSVLGSISIYSGLHPYALGMACGVGSGSMMTAAAGSLS
                     TMVPPEMADTILAYAATSNMMSSITGIIFLVFVSLPFTNFMYKILEPKFSRNKKTKEI
                     KSTEGEC"
     gene            15967..16437
                     /locus_tag="PC494_001506"
     CDS             15967..16437
                     /locus_tag="PC494_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3912010.1"
                     /translation="MFANLNLKKSSYQLLVMSVIGVIILIGQRISVGTSIVTALPGMV
                     MLILAAMAAMIIKDLFPKSIFPAFGFATIIGLLLSMPYSPTSEVFLTNTNNINFMAIT
                     TPLLAFAGISVGNKIEALKEMSWKIVIISLIVFTTIFFACASIAHIVLSIQGKI"
     gene            16450..17760
                     /locus_tag="PC494_001507"
     CDS             16450..17760
                     /locus_tag="PC494_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HDF3912011.1"
                     /translation="MNKEQLKSLVIKTIDENREKILKIGQGIYKNPEYGYKEFKTTEA
                     VSNFFEQELNLSVEKNIAVTGCKADANSSKKGPHISILGELDGISCKEHKDANEIGAS
                     HTCGHNIQIAGMLGAAVGLVKSGVLEHLDGKVSFMATPAEEFIELEYREQLKKEGKIT
                     YFGGKQELIKRGYFDDIDISMMFHASDLGEDKALVGPESNGFVGKKVKFIGKESHAGS
                     APHDGINALNAAMLAINNVNALRETFKESERVRFHPIITKGGDIVNVVPADVHMESYV
                     RARTINGMIDANERINKALMAGGMAVGADVEITEIPGYLPILRYKSLDNLFKNNLEDL
                     GLKGKVIDGGDFTGSFDFGDVSHIMPTLHPMIGGVKGALHTRDFEIVDEDLAYIIPAK
                     AMALTVVDLLFDNAKDAKDILDTFTPVMTKKEYLTFLEKHDKTL"
     gene            17972..18718
                     /locus_tag="PC494_001508"
     CDS             17972..18718
                     /locus_tag="PC494_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HDF3912012.1"
                     /translation="MFNAGNRIINTWLYPIQDGFVLIDTGYENGFKHFKKRISKFNIK
                     IKDIRYIFLTHAHDDHVGFLNQILDESPNTKIVMHDKALEILYKGQNSFIGGCTSRTA
                     FLFCQIMKLFGKGEHSFSPLKQEFEKRCILVSDKNRKEIEKELNGKIIDTPGHTDDSI
                     SLLIDDGVLFCGDSAMNGFPSTHKITIFAESKLEFIQSWKTIINTKPKMIYPGHGKPF
                     EYSKLEQNLIYVNKINLYPLHNSKDIHRFL"
     gene            19080..20621
                     /locus_tag="PC494_001509"
     CDS             19080..20621
                     /locus_tag="PC494_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbgT family transporter"
                     /protein_id="HDF3912013.1"
                     /translation="MNDNVVKKKNFFDRTLNRIETVGNKLPDPVTIFLGLCVLLLILS
                     SLVGSMGISVVHPGTGETITAVNLLTVEQLQILLGNIVSNFQGFAPLGLVLVTMIGAG
                     VCDKTGLMTATIKASVSKIPETRVTLVVMTIGMLANIASDAGTILFPPLAALVYLGVG
                     RHPLIGLFSGYAAVCLGFAANIMISVNDILAASFTVPAAQMIDSGFQANATMNLFFMI
                     ASTFVLILLATWVTEKIVAPRFGKYEGNAELDVDGSLSDVEKKGLKKAGISILIYVAI
                     IVALSVIGKKPFLADPETGDLLSNNAPLMKGMVPIIALAFFIPGVVYGKTIGKIKKDK
                     DVVSIMASAMSDMGGYIILAFAASQFLQLFTNSNLGLILAVKGGEFLKSAGINGPLLL
                     IGFIILSCFINLFIGSASAKWAILAPIFVPMFMMVGYNPALTQMAYRIGDCITNPLSP
                     LFPYFPIILAFTRKYDKDAGMGTVIANMIPYSISFLIVWTILLILFMVFNIPLGPGIL
                     PSYSM"
     gene            20656..21762
                     /locus_tag="PC494_001510"
     CDS             20656..21762
                     /locus_tag="PC494_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HDF3912014.1"
                     /translation="MLDKNRLINNFMDMVRIDSPSNQELEMSKWLVNYLKERNIDAII
                     DDAGEKYGGNTGNVIAYIKGEEGSRPLCLCAHMDQVQPCLGVKPILDGNVVRSDGTTT
                     LGADDKAGIAAILEALEHVITEKIPHRDIYLCFTICEEAGMHGVKNFNPDNLPCKDMV
                     ILDSGGAIGSIAYKAPAQQSIKISFQGKKAHAGIEPEKGLNAILVASHAISNMHIGRI
                     DSLTTSNIGEIEGGGATNIVTDKVTLTAEIRSHIPETLEYELNHMEKCCKDAASKFNT
                     TYTFEHNMSYPSFELSRDSHVFKLSEEAIRQVGVVPNPMVIGGGSDANILANLGYNCA
                     ILSLGMYDVHTVNEYVNIDELYDTAKIVYHMIKL"
     gene            complement(22141..23427)
                     /locus_tag="PC494_001511"
     CDS             complement(22141..23427)
                     /locus_tag="PC494_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HDF3912015.1"
                     /translation="MIVGIIGPSDSGFKIKDDLKQIDSDLKTKIYVREKVVDTIEVIS
                     KCEDECDAIIFTGCAVYEFIKSKYEISKPHSFVPRSGTSIMKAFWAIKSANIKLDKFS
                     IDVVDRYVVEDALKEFDIKATSVFCNPFSLEVGESELVEWHIKLFEENKTDIMLTGFG
                     AVYNELKERGYPVFRLQATIQLIKESYDKVKSEYALSKARFSQIAVEILSLIDYKEKI
                     DNYYSDMIKKSDMDKLVVNYVRSIQGSLFLLGRNDYVVFVHKGVADNEYNYDKLFNLK
                     REIKDMGFSLSIGIGTGVTAYQAENNAHKALRHSIDSKEIGIYLVDEDENIRGPLASE
                     NELNYSLMLSDEKVIEISKKTGMSCESVAKIIAINENRKSKIYDSKELAEYLNVSERS
                     ARRILNKIVNAGLGRICAKETSIGGGRPKNITEILF"
     gene            complement(23550..26648)
                     /locus_tag="PC494_001512"
     CDS             complement(23550..26648)
                     /locus_tag="PC494_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional diguanylate
                     cyclase/phosphodiesterase"
                     /protein_id="HDF3912016.1"
                     /translation="MDVINLIDELDEIVYVSSLDTYELLYINEIGKKAMGLNDISHLK
                     CYKALQGKDSPCEFCTNSILKEDEYYIWENTNTRTNRHFILKDKLIKWEGKHARLEIA
                     LDITEKEDISKSIAEKLEIKELLVGCIKHLITESNFSDAVNLVLTNIGKFHKADRAYV
                     FEVSEDRKKVTNTYEWCNEGVDEQKQALTNLDINELKNWFLLFEQKGFVIIDDIENIK
                     EEQPIEYEILKPQKIESLMTSSLKQDDKVVGFIGVDNPHKAVGDTSLLTSLSYFLLTE
                     MKKRKVENKLNYMSYYDFLTGAYNRNKYIKYIDNFQKGKVKSIGVVFVDINGLKDIND
                     NFGHANGDSAIVSACVIIKKYFHSYNVYRIGGDEFVVLCEDISKQLFEELVSWLSEEF
                     KDEMIYSVAVGSIWSDDNIDIHKLIKVADERMYQDKKRYYNKNKLRNNEMKVISDLAD
                     STNNILFKHKELVDKVYFDDLMIKGYSKAYEKLAYNTYDIILSICIDTNLITPIYQSE
                     SNIFSFPIKENLEKTFSYIKKHLIHPDDIILFNDNHLLKSLASLNNSKQDDLELNFEY
                     RRLGIDKKYYWALIYMLKISSKNKLGEKQTHILVAIKNIDYLMQLHKNQKDTLTGLYN
                     YESFCEQISLMLKRYPDKRYAIIMMDIDKFKVINDIYGVRGGDKALIYVAELIQKNIG
                     SNGICCRMYADVFCIFYESYSDRDIHKVIYKIKNSLNRKKFEYMLVPCFGVYRILDNH
                     IPITNACEMAGYAHKKVKKQSINNYIFYDDTIRNDALEEKQMEREMEYALENGQFHVY
                     LQPKYNLNANKIVGAEALVRWVHPEKGIIPPIKFISLFEKNGFIIRLDMYVWEQVCSL
                     IRKWIDLGEEPVPISVNVSRLHLHNPHFKEIVLSLINKYSIPKSFLELELTESLFIKN
                     IKLFTKIIADLRMDGIVLNMDDFGSAYSSLNMLKNINIDTLKIDCGFFNEEGITDREK
                     IVLKHTIAMAKDLDMDVVAEGVETKEQAEFLVSLDCVVIQGYYYCKPIPSADFEKLLY
                     QK"
     gene            27374..27532
                     /locus_tag="PC494_001513"
     CDS             27374..27532
                     /locus_tag="PC494_001513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3912017.1"
                     /translation="MKIFSFLLFVIGICLCIAGFIGHYPVFVGTTLSFLAIAMIAVRQ
                     VKTKKKMK"
     gene            complement(27819..28523)
                     /locus_tag="PC494_001514"
     CDS             complement(27819..28523)
                     /locus_tag="PC494_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF3912018.1"
                     /translation="MEIKPLVLIVEDDKPICKFIKVSLETQNYRCVETDNGGTAISLI
                     HSLDPDLIILDLGLPDIDGIEVIGRVRACAKTNKIIVVSAREHERDKVEALDGGADDY
                     LTKPFSVTELLARVRVALRNKAQQDNINNDAPKSFEVKNLKIDYENHIVSINGEEIHL
                     TPIEYKIIELMSKYSGRVLTHKFIIDKVWGNYYESENQSLRVFMASIRRKIEKNPAQP
                     EYILTEVGVGYRMADE"
     gene            complement(28514..30121)
                     /locus_tag="PC494_001515"
     CDS             complement(28514..30121)
                     /locus_tag="PC494_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4118 domain-containing protein"
                     /protein_id="HDF3912019.1"
                     /translation="MKKERLQHEDLKEYDYDEDGYLSKKIIIKDFIKTILVMTIATGI
                     SVVFEKVGFNESNIILVYILGVLFATSITYGYFFGILSSVIGVLSFNFFFTHPLYTFL
                     AYRKDYPMTFCIMLMAAIITSTLTSRIKREVRLSHKREKMIRLLYENNKTLLKAKNKN
                     QIIEFCGSNLVNILNRTVIVTIADENNNLGKPSIYICNNDGSENIFHSVLEKEAIKEA
                     FRTGNPVGIGTKYCKNSSAYYFPIKGQESNVLGVIGVACFKIDIITENEKILLEAVST
                     QVALAIDRENLFEKNKKANLEAERERLRGNLLRSISHDLRTPLTSILGSSSTILENDD
                     VIDKETRVELLKNIYEDTSWLTHSVENILSMTRIDEGKLDIEKRPEVVDEIIAESILR
                     VKKFANSRDIKTNIPDEIIIVHVDVLLIEQVLVNLIDNAIRHTPKNSKIELTVKKESN
                     QVLFEVADNGKGIPNEDIGNIFNRFYTKNKSRNLERRGIGLGLEICKSIVEAHGGEIV
                     AFNNPSGGATFRFSIPMYDEEGKDKWK"
     gene            complement(30375..31553)
                     /locus_tag="PC494_001516"
     CDS             complement(30375..31553)
                     /locus_tag="PC494_001516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3912020.1"
                     /translation="MEKLSDKRRVKAVSMETFVFIVLLAVGFGYVGSIMGAGMMFKVI
                     MSTAHALLLDTVFLIMAMAVLAGALSALLSEFGVISLVNKIFKGLMRPIWGLPGASIA
                     GVVATYLSDNPAIIPFAKDKTFTQYFKKYQVPALCNLGTAFGMGLIVTTFMIAQGKEY
                     VLPAIIGNVAAIIGSIISVRIMLTFTKKYYNYDPKNDTEKQINDKGAKLEEFREIRDG
                     NVFQRTLDAILEGGKLGVEMGMAIIPGVLVVCTLVMLLTFGPSTDPATGQAVYTGAAY
                     EGIKLLPAIGDKISFIIEPLFGFTSPEAIAFPVTALGAVGAAISLVPEFIKSGAITPN
                     DIAVFTAMGMCWSGYLSTHIGMMDALDARPLAGKAILSHTIGGLCAGICAHFIFMLVG
                     "
     gene            complement(31779..32273)
                     /locus_tag="PC494_001517"
     CDS             complement(31779..32273)
                     /locus_tag="PC494_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HDF3912021.1"
                     /translation="MHLFIEVIAAFFTALSFGVLFNMKGKNLILAGIGGSIAWFSYKF
                     LLNMGVTENLCFFIATVCFAIYCELCARIYMTPATTLSVCCLIILVPGYGIYNTMYSV
                     LTNNYIKAVEYGVSTLSCASSIALGLVFITTVFRKVNLYGVLTKIKENEKYKKSINKI
                     KQQK"
     gene            complement(32274..33035)
                     /locus_tag="PC494_001518"
     CDS             complement(32274..33035)
                     /locus_tag="PC494_001518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HDF3912022.1"
                     /translation="MDIDRILNFSSNAGKAMLQSGGETYRVEETIARICQSFGIDHVD
                     VFATPTAVMASVFVDGKLHSAIKRISSRRVDLNLVHEVNSLSRAISINNLDIELCEKI
                     LDEISEDNYYSDLITIFFAGIAAATFSILFGGNVEEFIAAFTVGILTKFVIMYLSKSS
                     LNDFFVNAIGAVIIASCSILILKLGFIKTLDHLIAGAIMLLVPGLALTNALRDLLDGQ
                     LISGLAKLAEVFFVGVSIAVGMFLVLGLYFKLGGI"
     gene            33737..36571
                     /locus_tag="PC494_001519"
     CDS             33737..36571
                     /locus_tag="PC494_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDF3912023.1"
                     /translation="MLRKDKVLLSLHKLCENMTLKDLQSDKTGFTTIEIANHSSLDRS
                     NTSKELNNLYNEKKVLKISGKPILFLHASIIENLIGRTLNSDEFSINNCNELLKSSKN
                     DSEDIFSTLLGHDSSLKLPIEKAKSAILYPPKGLNTLLIGPTGVGKSTFAETMYKYAV
                     ESKIFSSESKFVVFNCAEYAENANLLLSNLFGYVKGSFTGANKDKFGIVAQADGGILF
                     LDEIHRLPPEGQEMLFLLMDKGIYRRLGESDIVHKANVFIVCATTEDIHSSLLGTFLR
                     RIPVTINLPALQDRSLKERLSLIKYFFIIESKYTNATIKVHKDVIKSLLLYDCFGNIG
                     QLKSDIQLMSARAFLNYKTGLKDNIEIDLSIVPDYIYIGLLKLNENRSNLNKLSELDY
                     MLFYEFNGNNLEVEYTKELSKYNIDTSNNGFKYSTEIPYLENDIRSMFINYMEKYSTK
                     LLSISSVTHSDYTSNEIFKVINPKIYYAVEHSLKEAEKISRNKYTKQTYIALSMHISA
                     LIENINQDTYNPKYNLYNDKIFLDKDLNIAKIVLSIIENDLQTSLPKDEVKFISMFLN
                     SMYLEPNNQSESIGVIILAHGNSTASSMCDVANSLLGTNHCNAIDMPLDVKVSTILDK
                     TIELVKECDEGKGVLLLTDMGSLIAFGELISEKTKIKTRSIEMVSTPIVLEAVRKSTL
                     PEMTLDELANSLSSLNPYIGRAAIDSTEINYPEKSREYVIITTCITGYGSAMKVADFI
                     NSSLKNISKYNINLVPHNIESFKMYKNKFSNTKILAVVGSVDFNVANTPFIHIEELLN
                     GYGLDMLNKIIEGTFNANSITNIKETNLSYNSLIINFMTQNLELLDSVKLFNYVNSSL
                     FTIIELIDENLKSKFKLGYILHCSFMIERCFKNTTFPYNNITELISKNHELYSLIREA
                     FKPTEAYFNILIPDEEIAYIIDMINEYLNK"
     gene            36614..37858
                     /locus_tag="PC494_001520"
     CDS             36614..37858
                     /locus_tag="PC494_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HDF3912024.1"
                     /translation="MEDEILKGKIKQLTILALIFIFITPVFAFADTPPVPNSSRAALL
                     IDQETKRILFEKNIDEKMPLASLSKMMTFLLAIEAVDKNQVKETDMVKIDKSTASVGG
                     STCKLKDGDEISLGELMQGLMLVSGNDAAIAIAKHIGKTEKNFVNMMNKKAEEIGMID
                     TYYFNPNGLPIYTDPEHKEPPIENMSTAHDIVTLGKYMYDHYENQVTRITTMQVYNDT
                     KKDFTHYNTNPLLVSVPGVDGIKTGYTDNAGYCLAFSMMVPKDAKNERNHRLIGVVLG
                     DGNKKNRISSSATLLKYGKDNFHSKKIAHKGDIIETPCVDGIDDFKITVKVDKDLYGV
                     VSDNENINPKVVFKNMNYPIHKGDIVGVAKYYNDSGKFVGSVDVKSESNIGCIPLKDK
                     IKIKVAKINKKLEIKNSVCFKA"
     gene            complement(38273..40015)
                     /locus_tag="PC494_001521"
     CDS             complement(38273..40015)
                     /locus_tag="PC494_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF3912025.1"
                     /translation="MKKTINNNLFRILNIIVYKNKTKLIVSFIMVFIIAGVNIVIPQL
                     IRCIIDDGIGNKNIFLLINLILIYIFIRILSATFDVILSYLYTSIKNKVTINLKVKLL
                     NHISKLSGRYYSSKKTGNILSIMESDIFMIENFGAEIIFDIIVNVFTAIISLIFLINL
                     QFDLFLVVLFLQLILTFSQNKMTKLISKKISEIRSDSGSLSNLIQEYVSNIMDIVILN
                     SKKNFFNKYLKRERDLIKKDLNLNIIMSSNIAISQILTGLITILIYGIGGYKIINNKM
                     TMGELIAFQQYTGMLIGPCIAIVRANTRIAQSKVSINRVFSVIDEKIDIKVDNNGYRI
                     DNSEIKKIDFKNVSFRYGEDLNLVLNDINLQFEKGEVTGIVGGSGCGKSTITNLIYRL
                     WDINEGDILIDGVNIKDINLKSLRNNIDIVTQDQFVFDDTIKNNIVLNNKISDKELDE
                     ILEVTCLDDFIKNLDKGLDEVVGEKGVKISGGQKQRISIARALVSNKKVLILDEATSA
                     LDNISQKEILNNLKEYIQDKIVIIIAHRLSTIKSADNIYVLDKGRVIESGNDAELLHK
                     DGLYNKLVETADFA"
     gene            complement(39999..40673)
                     /locus_tag="PC494_001522"
     CDS             complement(39999..40673)
                     /locus_tag="PC494_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018590550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF3912026.1"
                     /translation="MKILKVKDLKKIYGKYENEVRALDGIDLDIEPHKFTAIVGASGS
                     GKSTLLHCVAGLDKPTLGNVYLDDVDLYTLNDDKLSEIRRQEFGFIFQSYNLIPVINV
                     YDNIVLPVLLDGKKEDKEYVMRLINKLGIEKQIKKYPNELSGGQQQRVAIARALANRP
                     SVIFADEPTGNLDSKTTNEVMNMLEWCVKEYKQTLVMITHNDNIAKTADRIITIKDGK
                     IDEKNY"
     gene            complement(40710..41699)
                     /locus_tag="PC494_001523"
     CDS             complement(40710..41699)
                     /locus_tag="PC494_001523"
                     /inference="COORDINATES: protein motif:HMM:NF012311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HDF3912027.1"
                     /translation="MTKVRIAVLDTGLDVNDDDINGNYVYDSNFQLKDLGGKEINDIN
                     GHGTFVSKTILNISKNTQIYPINIFNDSGKTSSLNLLSTLSKLTMSDIQIINISAASI
                     NSMYEKELEKVCNILNSQGRFIICSKHNKYEDKESIPTIFESVIGVVGNENIYKNNQY
                     IYEPENKIQMYANSKDNFIKFKDKVTHFGKNSKACAVATGIVANILKNNPYIKFNELE
                     EILIQKSKSKEDLKIENLNTPSYKSNLIRLDIARKIINVINRNFSKIKIDFEFVSEYS
                     LFNNFTCIGNYNAYNFLTILNKEFNISIDYKEVYLYQLENLDMAVDLIYENLI"
     gene            complement(41747..42991)
                     /locus_tag="PC494_001524"
     CDS             complement(41747..42991)
                     /locus_tag="PC494_001524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HDF3912028.1"
                     /translation="MNSSNKYFLDCICEKIINNNQVILSNKVNGRWVKIPIECYEVLK
                     YSVDNALQLGNLYDVFQENEDKKYYERVIDKLEHIGLLSDSILSEFRLERINKISFSP
                     TNRCNLSCDYCCVDSKIDNNDYLDTSQVRKVIDNIVKLNPRILTITGGEPLMRNDFLE
                     LLDYIKEKFKGKIILSTNATLIKEKQIDDIINGLYAIEISLDGYDELSCSEVRGKGVF
                     CKVLNVIRLIKLKKFENVGLSMVVGKNNEKDIEKFNKLNEDLGTTPIIRNFMNIGRGN
                     ENYSKYLNDKLDIDYICKDDYVDESSLCSNMCKAGVNQISIDHKGDVYPCPNLEYKDL
                     KIFNILEFNENILERILNREMDIFNIFDKLKPVNIESCKECKVNLFCTTCPSKIYTLK
                     NNKKMFDANCKKMKNILEPILW"
     gene            complement(43033..45579)
                     /locus_tag="PC494_001525"
     CDS             complement(43033..45579)
                     /locus_tag="PC494_001525"
                     /inference="COORDINATES: protein motif:HMM:NF014717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF3912029.1"
                     /translation="MINIKLAVSYLKRQKGKTLSLILSIGIAVMLVFSLSVINESQGQ
                     SDINHAYKNSGDYHAFYEDINSDIVKELNGEEDIKEFNDVLKFGEIISKDNGASLNLC
                     SYNKDFLDSTRYKLVKGREPRTSNELVIEQKVLDKMELDVKLNQTIDFQIVNEHINKN
                     NENSIYSKDKQFKIVGILSKSDEYYENLNKYKVRAFTYSNNGKDIVPYELITHMGTLK
                     LNTKDLDSQKVVNLGRKYKLTSNQFYPNTEVSMSMYMKNISKKTTYSIKQSLLPLLCA
                     TLVIYNMFNIIILDMTKQIGLLRAVGASKRNIRQVFFIQSIVVLSVGIVIGLLGGIVF
                     SYLGLMIVYDKSAELTINTNSIIESIIMSIIAVILASVVPIYKAGNLSIIDAIKKTDK
                     LNYIPRLLLLKSHKKVVGIINEIAFKNIFRNKVTSIIIIITISLCGVLFIGRLTSTKF
                     IYGKESDSANITSKSYGNFDIYLGYSPINANYTFSKYDNSLLNEIKAIEDVTDVEPNI
                     YLKGYLRNADLEEDYLDELKRTEINNNNESTVLIRGYNKELLNNIDKYIDKGENVYSY
                     TDRDYKNVLLVNNFYSRIKLSNNTQIIKSPKIGDLIDIKIPVYKDGEYKYINTKVRIA
                     GIMKNSYISEQDGESQSGGIQIIFNEKDLKELTGISDYNKVFVKIKKETDKKVIKEIN
                     NIIEKSGFSDIEGRYVRNHFGDHYNKSSYKLAMICVFGVLLISSINIIFIVRSNIIVR
                     LSEICTFRAIGMSKKNVKRMLIKENMIYGVLSMIVAGIISSFNYYKIVSETNKLNQQV
                     YGINNSIKFEIPIYEILIFGSISVFVCVIAVYFSNKMINKLSIVSGIKEN"
     gene            complement(45787..45948)
                     /locus_tag="PC494_001526"
     CDS             complement(45787..45948)
                     /locus_tag="PC494_001526"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3912030.1"
                     /translation="MIHIKKIEEKIELQDVEVQADPCKWYYDKHGIISQIDCMVDCAG
                     STPKGTVAY"
     gene            complement(46004..47020)
                     /locus_tag="PC494_001527"
     CDS             complement(46004..47020)
                     /locus_tag="PC494_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HDF3912031.1"
                     /translation="MKFTIFVTEDCNLRCTYCYEGNDKKKENMSYETADKTIDFICNK
                     ELESNSDYTTIVLHGGEPFINFDLIKYIHRDLVDRLSDKKILFDITTNGTIINDEIIE
                     FIAKNVKNISISIDGKKNIHDINRIDANGVGTYEKVMENGKRLIDKGIYVRARMTYNS
                     NTVKYLYESVYDIAKQGFKNIAPISDFMDKNWDNSHIKILNEQISKIMNIKKDYPEID
                     ISILDKQFINKKKGDCFGGINSYAIDTRGDVYPCTVCVGDKDILLGNIYDGLDDKKIK
                     NLIKIYISKNEECDGCTRLDYCMSTRCKLINKKVTGKFQSAVPIYCGLERVYVETTKK
                     LCSL"
     gene            complement(47017..48087)
                     /locus_tag="PC494_001528"
     CDS             complement(47017..48087)
                     /locus_tag="PC494_001528"
                     /inference="COORDINATES: protein
                     motif:HMM:NF015983.1,HMM:TIGR04085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HDF3912032.1"
                     /translation="MNKNQIFKSNNLNFDMLSNGVAIYFCLTNRCNLFCKHCCVESSS
                     NKKDLLSTYDLKNIVDIISVLNTPHIIITGGEPLIREDFFEIIKYIKQKLPDTKLILS
                     TNGTLIDEHNVDFIITNFEKIDISIDGVDENTCSETRGKGVFNKVISSVNLLKDNGFS
                     NIKLSMVFGQKNSHLNKQFKDLNKKLGTEFVERYFIPTGRGLENKESYLIEDTVLPIT
                     IPYILDNELKMCKDKKNKKMGCCACNAGNSQIFINYDGDVYPCPSLIKDDYKMGNIFD
                     NEFVKVIKENKTRDLKSLIKLESIYPYNFEKCKDCDVNIFCWHCPAILDSVKDNELEL
                     DRWCSMMKHNLNTAVWGDEKVN"
BASE COUNT        16130 a         7981 c         5286 g        18772 t
ORIGIN      
        1 gaaaataaaa taaactatct tccaaacatt ttattatatg cttaaaagat agttttgtgt
       61 ctttaaaata aattaaattg tatatattcc ttcacataac ttttgtatat tactaggtgg
      121 ttgccattta ccatcttttt tagtatatgt aatcatagtt gtaacttcct tagttggttt
      181 cttattgtaa aggtctataa tcatttttgt catatcatct tgaacttctt tttctttttt
      241 atcgtaattc ttttcatcag ttacataaga ttttactaaa gtgttcgctt cactcattac
      301 tttactagta tctaaagctt tacttacaac tttcaaagtt atcttatcct tactagaaga
      361 ttccactgtt actgtctttt caacaccttg aattaattta acaattgttt cgtatatctt
      421 ttcagcattt tctttaccat aaagaggtgt caattgagca atcattgaaa ccttgtcctt
      481 gctgttataa gtttgaatct gtttatattc agcttctgtt aatgcatcag aaattccttt
      541 ttcatcatac ttatacattt ctaatgcagc taaattagct tcaaaattcg actttacttt
      601 ttcttctgca ttagaacacc ctatagttag aactaaaact agagccataa tcgtagataa
      661 tattaacttt tttaccattt tcatacaaac atcctccctc aattaaaata ataaaaaatt
      721 tatttatcaa cattataaca taaatttgtc taactataga attattttga atattttacc
      781 acttccagtc tattccaata ccgttttctt ttgctttatc gtatattctt tttgctgtta
      841 cgacatcttg tacacctatc ccaacagttt taaatacaat tatctcatca tcatcttctc
      901 ttccaggaat agttccgttt ataacatttc ctaaatcacc actaaaatca tctttactta
      961 tcttaccttc ttttaatgga attaatatat ctcctgactc agataaaact gcatctgttg
     1021 attcaaaaaa tatcttagac gctctagtta aacagtttgg gcacaactct tgcatatctg
     1081 gcatatatga acctactgca cttattaaag ctcctttttt cactaagttt ccattaagta
     1141 ctggttgttt tgatggagta gctaaaacta tcacatctgc gttatctatg gcttcatcag
     1201 atgattcaac tgcaactatt ttagtattat atttacttaa ttttaagttc atttcttctg
     1261 caaatttttc tctactttcc ttgtttctac taaaaactct tacctcatcc aaatttctag
     1321 cttctatcat ggcttcaagt tgtggctcac cttgtcctcc tagacctatc aaagctccaa
     1381 tcttagaatc ttttttagcc aatacatcta tagctgctcc agaggctgct ccagtacgaa
     1441 tctgagttac ataagtacca tccaatactg cactaacttc tccagtttct ccatctaata
     1501 atagtactgt tgctggaatt actggtttgc ctttttgagc atttttagga aatacagata
     1561 caatttttat tcccccacag cctaattctt ctacatatcc tggcataaat aacatactag
     1621 catcttgact tggaacagat atattggttc tcaaaggatt tacactcttt ccttcacaat
     1681 aaattctaaa agcttcctta tcagcttcaa ttgcatctct cattgtaaat acttttttta
     1741 tgtcgtcttt ttttaaaagt agcattttta tacccccaat tttaataagt ctctatgcta
     1801 aatattatag cataacattt aatttaatct tctatttcaa atcaaataaa tctacatact
     1861 ctggttttag catagaactt atcaacgctt tatttattga aaattctggt attcctgctg
     1921 catatggagt tatatcatat aaatcaaaat atacaactag attctcatct tgcaagtaaa
     1981 agttttgatt ctcttttata cctttaaaat tatatattcc gatattttct tcatcctttt
     2041 tttcaagttc agctatttgt cttttaattt cttcatctat aacttcttta tatttagtat
     2101 tatccttaaa caagtccatt aattctaaaa attttccagt tctcatatcc acattatatg
     2161 ctatatcttg ataaaatcca tgtgctccac cactataagt ataatatctc acttttatac
     2221 taagagcaga atcagtattc tttttaagtt caaagtctac atttgcaaca aacttatttt
     2281 tctcgtcagg attatcctta agatactgct ttgcttcttt atatgattta ttataaaatt
     2341 caaatatgtc attttttatc ttatcatttg tagacctttc aacaatttta tttgaatttg
     2401 ttattacagg catgtttata gtactttcta aatactcatc atttttcact attgttttac
     2461 ttcctattgt acttactgat aaagtttgtt tactatttgt attacccttt ggtaatgact
     2521 ggttactcat aacagtcact gcttccttat tactatttaa attaattgaa gcatctttcc
     2581 ttaaattatt atatttatag tcatgtttaa ttgccaaaac agccattata gtcaatgtta
     2641 aaacaaatac atatcttaaa actttagctt ttgtatcgac tttaaaaaat ttcatattat
     2701 cattttcctc ctaaatataa atctctctta ttatatttgg agtttctagg gttttttatc
     2761 catataattt aataaaagat taatttttat ttataaaaaa ttaatctttt tgttttaaaa
     2821 tattaatatg tcttatcaaa cagtttgaaa tttcaccaag aggtaattgt aacataacag
     2881 aacctctatc aaaagctacc attggcattc catatactat acaagaattt tcatcctgtc
     2941 caattgtaaa tgaaccattt tctttcattt ttaaaagtcc acttgctcca tcataaccca
     3001 tacctgtaag tattattcct attgaatttt tacctgctac ttctgctact gaatcaaaca
     3061 aaacgtctac tgatggacag tgaccactta ttctttctcc tttttcacaa gttacataat
     3121 atccttgttt atccgtacac aatttcatct ggtaaccccc aggtgcaatt aacacatttc
     3181 cttgttctac tctatcatta ttcttagctt ctcttacatt cataatacac tgcttgtcaa
     3241 gccgttgtgc atacatataa gtaaatatag ctggcatatg ttgaactaca acaatccctg
     3301 gtgttgattt tggtaggtct tttataattt caagtattgc ctctgtacca cctacagatg
     3361 cgcctatagc aataaccata ttattaaaac gttccacatt accgcctcca aaaaatcata
     3421 tatcaaaaat acctttttat cgtttatata tagcaggttt tacatatttg tatttagtac
     3481 tacttctgtt gattacttct gcatgtccta caaacaaaaa actatctttt ttggtagcat
     3541 tataaaattt atttataagt tcttctcttg tttttaaatc aaaataaatc ataacatttc
     3601 tacaaaaaat caaatcaaaa tgttgatatg agaaatcatt cattaaatta aacggcttaa
     3661 aaattacact ttttctaatc ttatcacaaa ttttaaatgt accatccttg ttgtctataa
     3721 aatacttctt cttccataac tcaggaacat tgttaacatt tgattctatg tatatacctc
     3781 ttttagcttt ttcaagtgag ttagttgaaa tatctgtggc tatgatttta atgttccaca
     3841 actctttatt atatccaaaa taatcatcca aagtcatagc tattgaatac gcttcttctc
     3901 cactagaaca tcctgcactc catatattta tgtttcttat tttattattt tcttcccaaa
     3961 aaggaagtat actattctgt ataaactcaa aatgttgagg ttctctcata aaaaatgtgt
     4021 ggttagtact caatctattt attaggttta tagcttcatt tcctgtctta tctttaaata
     4081 atagattcat atattgacta aaagaactaa gttttttctc tatcattgta ttgtataagc
     4141 gaccttcaat taacgctctt tttttactta aatcaatacc atattctttt tttacatggt
     4201 ttacaagaac tataaattct tcatctgtga gttttatcat gcaaaaactt cctcctgcta
     4261 atttatcaga actaactata tgctattaat caaaaacttt cgaatatcta aaattaatat
     4321 agaattatct tcaactttcg caatctcttt tatatcttta ttaatattag tgttgttaga
     4381 attagtcgtc tctagtaaat ttagattttc tatatgaata acatcaacaa ctttatctac
     4441 aataattcca acttgatact catcaacctt tgtaattatt atacaagttc tctcattata
     4501 atcagcttta ggaagattgt actttatatg catattaata actggtatta ttcttcctct
     4561 caaattaata actccactta tatatgttgg aagacatggt acatacgtta ttgattgaaa
     4621 tcttatggtt tcaatcacat tttctaattc tattccataa ataacatcat tgacataaaa
     4681 tgttaatact tgtttaataa tttcatcttt agccatactt taaatcccct aatatatttc
     4741 tataatgcta tctgcatcta taattaaact tatacttcca tccccaagta ttgtacatcc
     4801 cgataaaccc ttatttttta tattaaatcg gttaaaataa actggaaatg gtttcacaac
     4861 aacttgctga ttacctatta tttcatcaac aaaaatgcat actgctttat gctcattttc
     4921 aataattatc atattaccat tcatcagatt ggttactttt gtttgaatat tatatatttt
     4981 atgtaacctt ataatgggaa tacatgctcc atatattgta attaactctg tcttatttcc
     5041 ttctgtaatt atttgattta agtctgtaag tttaaatgtt cttcttatgg atgatattgg
     5101 taaagtaaat agtgaatctc caactttaaa cttcataccc tctactatag aaagagttaa
     5161 tggtattttt atagtaaagg ttgtcccttc atcctgttta ctttttactt caattgaacc
     5221 tccaactttt tcaatacttt tacgaacaat gtccatgcct actcctcttc cagaaaattc
     5281 agttatagat tcttttgtag aaaagcctgg agtcataatc aaagaattga cctcgtcatc
     5341 agtatactca ttactttgat gtttaagaag accttgttcc ttagcttttg ccaaaatctt
     5401 atctctcata atgcctctac catcatctga aatacttatc acagcttctc cgcctagatt
     5461 ttcagcagat aaaactattt ttcccacttc ttctttacct ttcgctatac gctcctcaat
     5521 aggctctatt gcatggtcca tagcatttct tataaggtgc ataaaaggtt ctgctaaatt
     5581 atcaattaca ctcttatcta cctctgtctc tgctcctata gttattaact ctacattttt
     5641 atctaatttt ttattcatat ctcgtacaat tctatgcatt ttttgaaata caccagcaat
     5701 ttgaatcata cgcatagaca ttactatatc ttgcaattca tctgtaagct tgtgtaattg
     5761 tcttgttgcc ttattgaaat tatctatatc aacacctgta gaatttacgc tatttacaac
     5821 cattgattcc ataattacaa tttctccaac tatattttga agtaagtcca atttttctaa
     5881 atttacactc ataatactct gcttacttat tggtaaatgt tcattttctt cacttagact
     5941 atctttttcc atatcagttt tttcatttaa aacatcttct tgtatctcat cttctgtata
     6001 gttattttga taacttttac ttactttatt attatctttt aatttatttt ctactgcatc
     6061 attgtttgat gtatttttca tttctatttc ttttttacta atatttatgt attcttttac
     6121 atagagatta tcttctatag ttttataaac tattgcctta tcctctttag ctacaaattg
     6181 tatataaaac ccataacttt taatatactc tgtagactct gcatttgttt ctacatcttt
     6241 tggataaaaa tctataaatt cacagtaatc tctaagttca aatacaagca tgaaagctct
     6301 cacattttcc atcatgcaac cttgttcaaa gattattttt actacatcag agccttcttt
     6361 gtattcaaaa tttgaatcta ttacttcttt ttcgtctgta ctttctaaat ttgcattatc
     6421 ctttgatttc atagaacttg ataattccaa agtactcaca tactcttcaa ttccttcaat
     6481 aaaattagag taatcagaag atatacaacc tcttgattgt aactcatcta tatctcttct
     6541 tataaaatct aatgattgaa agactaaatc aaataatagg tcattgtcta aaacttctat
     6601 tttaccttca cgtatagcat aaaacaagtc ttctacacta tgtgctaaag cagatatatt
     6661 gtctaacccc atcatagatg ctgaaccttt tatcgtatgc attattctaa aagtttcatt
     6721 aatgttgtta tgagtaaata ctttctcttt ttctatttga atcataattt catctaattg
     6781 ttcgagtaat aaacttgtct caaatataaa catatctaac atttgtctca tactcggttc
     6841 aatataattc acatttatca cctacgacct acaaataatt ttctattata tatgcatctc
     6901 ataatttaaa tccttgatga ttctcttact tcaatattca cctcataatt taaacccatg
     6961 atgattctct tacttcactt tcctttagat gaaatttttc tactaattct tttaaaattt
     7021 gagcttgagc agacatctct tctgaggctg ctgcactttc ctctgctgtt gctgagttca
     7081 tttggactac tatggaaatt tgctctattc cagataaaat ctgtgtaatt gctacttctt
     7141 gactatgtac agccgaagaa ataccattaa tataattagt agttttttct acaccattta
     7201 ctaccaagtc caatgcattt gcagtctctt tagcaattct gacaccattt tctactgttt
     7261 taatagcttc ttctatgaga atagctgtat tttgagctgc ttttgcactt ttaccagcca
     7321 aagacctaac ttcatctgct acaactgcaa atcctctacc atattgacct gctcttgctg
     7381 cttcaacagc tgcatttaat gcaagaatat tagtttggaa tgctatctca tctattgttt
     7441 tgattatttt tgatatttca ctcgattttt cacttatttc acccattgat gtcatcatat
     7501 catccataca tctacttccg aaaccaactt gtgatgcaga ttggtcagat acctcacatg
     7561 caagactagc actatctgca cacttcttaa ttccatctga tatctcatta atcgtggaag
     7621 ctaattcttc tactgaacta gcttgttcag tagcaccctg tgaaagagct tgtgcacctg
     7681 ctgcaacttg ttctgaagca cttgcaactt gctctgctga taaatttatt tcagaaaaat
     7741 caccattaaa agagtttatt atactttcta aagatatttt aattgattta aaatcaccta
     7801 taaattcttg gtctatctct actcttaaat ctccttttgc aatactagtt aatgtactgt
     7861 ctataaggtc tatgtaattt aaaagcatac tttgcatctt tttgacagaa ctcactaata
     7921 gtcctatttc agatttactt tcttcaacgt ctatacttgt tcttaagtcc ccagatgcaa
     7981 ttcttgaaaa gtgtttttct actttattaa taggaatcac tatttttaat tttattactg
     8041 tatattctat tattgtcaat attattaaaa gggaaagtat aaatattgtt cttaatatta
     8101 gactttgtaa ttcttttttt acttctacaa ttttggaatt tgaacgggta actatatcct
     8161 cttgaaattc atttattaaa gaatccattt tctcttggga gtttatatag tcactaccaa
     8221 aaattatact ttgagcttta ctcttatcat tactttcgac tgcctttatt gcactttgtt
     8281 ctgttggtac taaagaatct gatatttctt ttgcttctaa gattttattt gactcgctct
     8341 ttgtaagacc aattttttct aatttgttta aagctgattc tcttgttttt ccgtataatt
     8401 ctttttcata aatatcttta ttcttttttt ctcctgtaaa tacatatctt cttaatacat
     8461 cacttatctc tctagttgta tcttttatat actgactttg agtcctcaaa ttattcatat
     8521 cattaatact tttttctact ttttcaaatg ctttataaga tgaaatagaa gaaaaaatcc
     8581 ctgctagaac agccaatact ataataatca gcaatacaat tgctaattta gaaagcttta
     8641 cttctctttt catatctgta ctccttcata aagtaagttt atatcttttt taatcctttc
     8701 attgtactca ctacgctaca atcttttcct aagtttttac cctcatacat tgctttatct
     8761 gctaaggata tgttttcttc taatgatata tttgagttta cttctactac tcctaatgta
     8821 atagtgcact ttattttatg ttctttatag ttgaaatcaa actcctttat ctctttacgg
     8881 attctttctg aaagtatctt agcaccttct attggagtat ttgtgagcat tatcaaaaac
     8941 tcttctccac cccatcttga tacagtatca atttgtctac aattcttttt tattatactt
     9001 gatattactg ttaacacgaa atcccctgct tcatgcccat aagtatcatt gataacctta
     9061 aagtcatcaa tatcaccaag gataagggat attgatgttt cactatattt attaattctt
     9121 ctttgctcca taagctgatt aattatatgt cgcctattgt aaagacctgt aagataatct
     9181 cttacaacga gtctattcaa tttttcaaga gaagattcca gttcattatt tatctttttt
     9241 agtttatctt gagatttctt tacttcaaga tgagctataa cacgagcttt taattctgtc
     9301 atactaaaag gtttcaccat atagtcaatt gctcctacac caaatccttt tactatgtct
     9361 gtatctgtat tttttgaagt tataaaaatt ataggtatat ctgctgtacg agcattagat
     9421 tttacttcct tacaaaactc aaaaccagaa ttatctggta aaattatatc aagcaaaata
     9481 atgtctggta taaattcttc aataaattct tttgcctcta ttgcattaaa tgctttttta
     9541 accttaaaat tatcttttgt aagtgtttta tctattaagt cacacatcag aacactatca
     9601 tcaacgacta aaattgttcc ctgttgctta tttttcatat acaaacctct cttaaacata
     9661 atatattcaa attttaatga tttaaaattt ttatacttaa taattatacc actatattct
     9721 taaatgttct catcacaatc tttttataat aacactccaa ctacatccct atattacatg
     9781 atagtgcaat caaacccatt gattaattca tctattaaaa cttcatcttt atctgtcaaa
     9841 agtttctcta aatctagtaa agtaattatt ttaccttcta attctccaac tccacttaca
     9901 aaataatccg aatattctat agtaactctt ggtggaggtg atattttact tttttctaag
     9961 cttactatat catcaactct atcaaccaca aatccaacta ccaagtcctt tatttcagtt
    10021 actactatat acatgcaatt tgtagtcatt aattcatctt ttttaagtct caaacgcata
    10081 tctattatcg gaatgatttt tcctcttaga tttattatgc ctttagaata tgtaggtagt
    10141 tctggaataa atataatttc ttgatttcca gtaatttcta ttatcttttc aagttcaacc
    10201 ccaaaatctt gctcatctac tttaaacttt agatacttaa ttccttcatc aattagtcca
    10261 taatctaaat atgggtcatc tggaaatctc atttaatacc tccctcctaa aatacacttt
    10321 ctatgaaata tatattataa tttcttctta cctttattta ttgaatctac aagtaattca
    10381 cccgtctcag tgtaaaaacg tattgttcta ccataattca tacctgtatc ctcagctaat
    10441 attggaatat ttaatcctaa aagagttttt tttactgcct caacattcct atgtcctata
    10501 cttgcaatta ctgaattgct acttcctaaa aacatctgag cacctccagc aatttttgct
    10561 tttatatata ttctatttgc acctatattc tccatagatt taatgagctc atttattcct
    10621 gtgtcagcaa atttacactt attttcaatg ttaatagcat ctttactata tggcaacata
    10681 acgtgtaaca ttccaccaat tccagctact ttatctatca aacatactcc tacacaagaa
    10741 ccaagtgcat aagtaactaa aacatttggt ctataggcta tcttcatatc tgcaatgttc
    10801 actactatct ctctattcat acctctaatc ccaacctcac gagtatctct ttaagtgagc
    10861 tcatttctgg aatcatcaaa atgtgactag taaaataatt atcactcatt ttaaatttat
    10921 tttctataaa taagactttg tcaccaacat ctgaaaatct tatcataggt acatttagaa
    10981 cagctccaac catatcaata catatatctg gaattgaaac acttatagtc atgtttaaca
    11041 tagatgcaat agcatttaca tatgaacttg ccataatatt tcctatttcc ttaattgctg
    11101 aaatttcaat tgcctcaatc tcatctaaaa aagcttcttc tttattaaaa agagaactta
    11161 gcataagttg agttattgat tcatccaaca aaaacataaa cattccattg atatcacctt
    11221 tcatatcgag taaaatacat actactttgt tttctggacc accaagcaaa tttgtcgctt
    11281 cattatattc aagtatcttg accataggta ttaatacttc tacattgcta tttatcatgg
    11341 atgcaagtgc agtaattgca ttcccagagc ctatattacc aatttctcta agagcatcta
    11401 tatgaacatc atcaagttct aaataattta taatataaac ccctcccttt attattgcat
    11461 ttatttgctt ttcattgtat tagtgtatat ttacactttt attttaaagc attatctaca
    11521 actttaacta atgtttctgt tttgaagggc ttcactataa aatctaacgc tccaagtttt
    11581 atggcttcta caatcatatt ctcttgtcct attgcagagc acattacaac cttagcactt
    11641 gaatccaact tttttatttc tcttagcacc tctaaaccat ctttttttgg cattgtaata
    11701 tcaagcaaca tcaaatcagg cttttcatat ttaaatatat tacacgcttc ttctccatca
    11761 tttgcttcta ttaaattatt atagccactt ttactcagag cttctttaat tatcattctc
    11821 ataaaaatag catcatctac tatcaaaatt ttattttcca taaaactaac tcctccatat
    11881 gtacaacaat aaacgctttt atcttcagtt attgtctata ctatctgact atttttcgct
    11941 acacaataaa tacatttcat tgataaataa aagtaattat ttatgccata ttatacttaa
    12001 ttctcttaac ataatttgtc aacaaaaaaa cttatatatc tattgtaata tatgtttggc
    12061 gttttgacga gttattaaaa atataattgt ataaaacata aaaagttatc aaaagtaatt
    12121 aaattataat aaaacaactt tatacctttt ttatgtttgt ataaaaaaaa ttttcagatt
    12181 cattaaaatc atttctgtag attcatatag gatttgactt tctcaatatc taatagatag
    12241 ttgtttattt acttaattat atttctctat atgtattatc gattaaatta gatttagctt
    12301 tataaattat tttttatatt tttcaaattg tatactcata aatccagaag tattctaatg
    12361 tgtttataat actttttttc atattttaaa ttaaataaca aatcattata tttacaagta
    12421 tcatttatca ataaacaata ttaaatgaag aatatgtctg aagattcaaa gtgatactga
    12481 tactattaat tactaaaaaa gcagtaaatc ttttacagat ttactgctta tagttataaa
    12541 taataaaact atctataata aatgtactat actcaatatt tcattcaata tagtaataac
    12601 aaatctactt tattcctatg taaatatgaa tttcttgttt ctttgtatca aaagtattac
    12661 attgatactc ttcaaaatca cttatataag tcctatcaaa atccatttgc caaaactcaa
    12721 accaaaaatc tcctacttct ttttgacctc ctactataac aaactttgca tacttacctg
    12781 ctggtataac tttactaata atactttctc caacagtatt attagtgttt aattcttcta
    12841 aattcttctc tttatcagaa ttactattta cttcacaaca tgcaacaaag ctatacggac
    12901 ttgtaaaatc accctggtaa tctgtatata gacctattgt cttgtcattc tttttaccct
    12961 ttatagcatt atatatccct ttgcccataa attttttcca caattcacct atatcattta
    13021 ccgcttgtcc atctttattt gtagtctcct tcgatattcc tataactatt ttctcattta
    13081 tctctactat ttcataattc atactttata cctcactttg tttttattaa tctattttat
    13141 tttgaactaa ttcaattata atttataata tacgacacct ttatgtcata tttttaatat
    13201 aattaaactc agtgagatat tatatactaa atgcaagata ttatatattt aataaaatct
    13261 ttaatctagc attatattat aatgaataaa ttttagacaa ctcccttagt ctagttatta
    13321 cattatccct aacatcttta ggttcaagta cttcaacatt gtcaccaaat gataaaatat
    13381 atccataaat ccattcacca ataggaaatt ctgtaattac atcatatgta tcatcttcat
    13441 ttttagttat taaatcctta ttaaaatcat caaatactct aaaaagcatc ttttctttaa
    13501 acctcaattt caacgttata gtattttcct taattacttt agaatcattc aaacatactt
    13561 cttctattat ctttcttgaa aatacttcat cctttataga taaattcctt atcctactaa
    13621 ttctaaatat cctaaaatca tcttttagtt tacaaaatcc atacaagtac caagtcttac
    13681 tcttatacat aagcttcagt ggttcgacag ttctgtttgt ctgacttgac aaactattta
    13741 cataattaaa atttatagta ttacgcctta aaatagcttc ttttattttt gtaaatttat
    13801 catcttcatt aaaattactt ccccattcag taaagtctat ttcaatccag tttgaaaaat
    13861 tctgctctcc aaatattgag ccaattttat ttactactga atttatttct ggatacttag
    13921 tcgcctgtaa tgttttcagt gcaactatta aactctcttt atcttttttt gacaatatag
    13981 ccttgtctat agaatattct tctattaaag atatccctcc tcctttgcct ttcgtcatat
    14041 atactggtac tcccgacata gacagagttt ctatatctct atatatggtt cttgtagaaa
    14101 cttcaaatct atctgccaac tctttagctg ttactaattt tttatttaat agaattacta
    14161 ttatttctgt taatctattt attttcattc attaccacct actaaaatta ttaaatttat
    14221 ttaatctaaa ttaatcatac taatttttaa ataaataaaa tcttagaatc ttatctaaat
    14281 tatttttaca tgattttatt tactttctat tatctttctc actttggata ttatcatctt
    14341 aatttattta ttactatatc aatttactta ttatcatctc atttgttatc gtcttactta
    14401 atttacttat ttctatatca attcacttat tattacctca cttgttatca tcttacttaa
    14461 tttacttatt tctatatcaa tttacttatt atcatctcat ttgttatcgt cttacttaat
    14521 ttacttattg ctatgtcaat tcatttatta ttatctcact tgttatcgtc ttacttaatt
    14581 tacttatttc tatatcaatt cacttattat catcttaatt catttgctta ttatcattta
    14641 ctttattcaa tttctatatc aaaattagta tttgtactta atacttaaaa ttaatttaaa
    14701 gtctttacat attatttatt ttctattgta atattcattt ccatacttta ctaagctact
    14761 tccactcatt tattttaaaa tttcaattta ctatttctca actctatatt attatttttc
    14821 aattttatat tactaatttt aaagcttttt agctattatt cctacaatat ttaaacaatt
    14881 ttttcataat aaagctatat tacaatatat tcaaaatatg taatatttta gatatttttc
    14941 gttgacaatg ttaaattttt gttttatcct taattaagga catgttattg acatttctga
    15001 aacttatttg aaatagtttt ttcattttat ttaggaaaac gtattatact taagaaaacg
    15061 tattttctca tttcagataa gtaaaatatt tattcttttg gggaggaaat catggaaatt
    15121 aataaaaaac attttattca agtattttta acttgcttaa tcttggtagt aatatgtgaa
    15181 tttatagggc aaagaactat agctattgga aaagcctcta tagtactgtt ccctatgctt
    15241 tatgcagtta taattggact tataataaca ccagatttat taggtaaaaa aattaaagca
    15301 cttaaaaaag tggttggaga aaaagaaata aatattgctg gtgaagttgt tggaattgca
    15361 ctagtaatgc ttggtataaa atatggtact acagttggac caaacattga caaaataatt
    15421 caagctggac cagcgtttat cgctcaagaa tttggtcata tacttgcacc aatcgttgca
    15481 ttacctcttg cattaatgtt tggaatgaaa agagaagctg ttggagctac tgcaagtata
    15541 agtcgtgaac cttctttagg agttatatca gaaaaatatg ggataaactc accagaaggt
    15601 agtggtgtac ttggtacata tttaatggga acagttcttg gtactatata ctttagtgta
    15661 ctaggttcaa tatctattta tagtggtctt cacccatatg ctttgggaat ggcctgtggt
    15721 gttggtagtg gaagtatgat gacagcagct gctggttcat tatctaccat ggtaccacct
    15781 gaaatggcag atacaatact tgcctatgct gcaacaagca atatgatgtc tagtataaca
    15841 ggaattatat tcttagtttt tgtatcctta ccatttacta attttatgta taagatttta
    15901 gaaccaaaat tttcgagaaa taaaaaaact aaagaaatta aatctacaga aggagagtgc
    15961 taataaatgt ttgctaattt aaatttaaag aaaagttcat atcaattatt ggttatgtct
    16021 gttattggag ttataattct tataggacaa agaattagcg ttggtacatc tatagttaca
    16081 gctcttcctg gtatggtgat gctaatatta gctgctatgg cagctatgat tataaaagat
    16141 ttatttccta aatcaatctt tccagctttt ggatttgcaa ctataatcgg ccttttactt
    16201 agtatgccat atagtccaac atctgaagta ttcttaacta acactaataa tattaacttt
    16261 atggctataa ctactccact actagctttt gcaggaattt ctgttggaaa caaaatagaa
    16321 gctttaaaag aaatgtcatg gaaaatagtt ataatttcac ttattgtatt tacaactata
    16381 ttctttgcat gtgcgagtat agctcatata gttttaagta ttcaaggtaa aatataggag
    16441 gaatttatta tgaataaaga acaattaaaa tctctagtaa taaaaactat agatgaaaat
    16501 agagaaaaaa tattaaaaat aggtcaagga atatacaaaa atccagaata tggatataaa
    16561 gaatttaaaa ctacagaagc tgtttcaaac ttttttgagc aagaattaaa tttatctgta
    16621 gaaaaaaata tagcagttac aggatgcaaa gcagatgcaa attctagcaa gaaaggtcct
    16681 catatatcta tacttggaga attggatggt atatcatgta aagaacataa agatgctaat
    16741 gaaataggtg cttctcatac ttgtggacat aatattcaaa tagctggaat gttaggtgct
    16801 gctgttggtt tagtaaaaag tggcgtttta gaacatttag atggtaaagt atcttttatg
    16861 gctactcctg ctgaagagtt tattgagttg gaatacagag agcaattaaa aaaagaagga
    16921 aaaataactt attttggtgg aaaacaagaa ttaataaaaa gaggttattt tgatgatata
    16981 gacatatcta tgatgtttca tgcttctgat ttaggagaag ataaggctct agttggtcct
    17041 gagagtaatg gatttgttgg aaaaaaggtt aaatttatag gtaaagaatc tcatgctggt
    17101 tctgctccac atgatggaat aaatgcttta aatgcagcaa tgcttgctat aaacaacgtg
    17161 aatgcactta gagaaacttt taaagagtct gaaagagtta gattccaccc tatcatcaca
    17221 aaaggtggag atatagtaaa tgttgttcct gctgatgttc atatggaatc atatgttaga
    17281 gctagaacta taaatggtat gattgatgct aatgaaagaa taaataaggc tttgatggct
    17341 ggtggaatgg cagttggagc tgatgttgag ataactgaaa ttcctggata tcttccaata
    17401 ttacgataca aaagtcttga taatttattt aaaaacaatc ttgaagattt aggtctaaaa
    17461 ggaaaagtta ttgatggtgg agattttaca ggctcttttg attttggaga tgtgtctcat
    17521 ataatgccta ctcttcaccc tatgattggt ggtgtaaaag gagctcttca tacaagagat
    17581 tttgaaatag ttgatgaaga tttagcttac ataattcctg ctaaagcaat ggcacttaca
    17641 gttgtagacc ttctttttga taatgctaag gatgctaaag atatattaga tacctttact
    17701 ccagttatga ctaaaaaaga atatctaaca ttcttagaaa aacacgataa aactttataa
    17761 gtctattttt ataatagggt ggtatctact gtaaaagtta taccactctt tgtttttgta
    17821 acagtatact tcttttcttt tagtttttag attaaactaa aatatattat cctccttaaa
    17881 acttttagag ctacgttgaa atatcagtag aactatgcta tattctttct aattaatata
    17941 aatttctatt ctaattcaag gtggtgaaaa aatgtttaat gcaggaaatc gaattataaa
    18001 tacatggttg taccctattc aagatggctt tgtcttgatt gatactggat atgaaaatgg
    18061 ttttaaacat ttcaaaaaac gaatttctaa attcaacata aaaatcaaag atattcgata
    18121 catatttcta actcatgctc atgatgacca tgttggtttt ctaaatcaga ttctagacga
    18181 atctcctaat acaaagattg ttatgcatga taaagcttta gaaattctat ataaaggtca
    18241 aaactctttt attggtggtt gtaccagccg tactgccttt ctcttttgcc aaattatgaa
    18301 actatttgga aaaggtgagc atagtttttc tccacttaaa caagaatttg aaaaaaggtg
    18361 tattcttgtg tctgacaaga atcgtaaaga aattgaaaaa gaactaaatg gaaaaattat
    18421 agatacacca ggacatactg atgattcaat ttcactacta attgatgatg gtgttttatt
    18481 ttgtggagat tctgcaatga atggatttcc aagtactcac aaaattacca tatttgcaga
    18541 aagcaaacta gaatttattc aatcttggaa aacaattatc aatacaaaac ctaaaatgat
    18601 ttatcctgga catggaaaac catttgaata cagtaaatta gaacaaaatc taatctatgt
    18661 aaataaaata aatttatatc ctctacataa ttcaaaagat attcacagat ttttgtagaa
    18721 aatacaaagt aaatttcttt gattaattaa aaaatctaac actttactac gctacttatt
    18781 ttaataactt aatcttccac tagcttttca taaaattttg ttttaaaatt aattttaaag
    18841 cgcatatgtt atttaaatac attagatata attcgtcatt aatctactta aagcatattt
    18901 aactaacacc actcaaccag aaaattcaga aaactgcatt gacacaggaa aaagtttatt
    18961 ttatactttt tttaggacat attgtggaca cgtcttaaat cgacaagcag aatttaaatt
    19021 gtaagattaa ccacaatact tattttttaa ttatattttt aaacattagg gaggatatta
    19081 tgaatgataa cgtagttaag aagaaaaact tttttgacag gacattaaac agaatagaaa
    19141 ctgttggtaa taaactacca gacccagtta caatattttt agggttatgt gtacttttac
    19201 ttatactatc tagtctagtt ggttctatgg ggatatcagt agttcatcct ggtactggag
    19261 aaactataac cgctgtaaat ttattgactg tagaacagct tcaaattctt ttaggaaaca
    19321 tagtcagcaa tttccaaggg tttgctcctt tgggtctagt tctagtaact atgataggtg
    19381 ctggtgtatg tgacaaaaca ggacttatga cagcaacaat caaagcatca gtaagcaaga
    19441 ttcctgaaac aagagtaact cttgttgtaa tgactatagg tatgcttgcc aatatagctt
    19501 cagatgcagg tacaatatta tttccaccat tagctgcact tgtatatctt ggtgttggta
    19561 gacatccact tataggttta ttttctggat atgcagcagt ctgtctagga tttgccgcaa
    19621 acattatgat aagtgtcaat gatatacttg ctgcaagttt tacagttcca gcagctcaaa
    19681 tgattgattc tggatttcaa gccaatgcaa caatgaactt attttttatg atagcatcaa
    19741 cttttgttct aatacttttg gcaacatggg taacagaaaa aattgtagct cctagatttg
    19801 gtaaatatga aggaaatgca gaactagatg ttgatggaag tcttagtgat gtagaaaaga
    19861 aagggcttaa aaaagctggt ataagtatat taatatatgt ggctattata gtagctctta
    19921 gtgtaatcgg taaaaaacca ttcttagctg acccagaaac aggagattta ctatcaaaca
    19981 atgctcctct tatgaaaggt atggtaccta taatagcact agcatttttc atacctggtg
    20041 ttgtatacgg aaaaactata ggtaaaataa agaaggataa ggatgtagtc tctataatgg
    20101 ctagtgcaat gagtgatatg ggtggatata taatactagc atttgctgct tcacaatttt
    20161 tgcaattatt cacaaatagt aatttaggtc tgatactagc tgtaaagggc ggagaatttt
    20221 taaaatcagc aggaataaat ggacctttat tgttgatagg atttattata ttatcctgtt
    20281 ttataaattt atttataggt agtgcatctg caaagtgggc tattcttgca cctatatttg
    20341 taccaatgtt tatgatggtt ggatacaatc cagcacttac tcagatggct tatcgtatag
    20401 gtgattgtat aacaaatcca cttagcccat tatttccgta cttccctatt atactagcat
    20461 tcacaagaaa atacgataaa gatgctggta tgggtactgt aattgctaat atgataccat
    20521 actctatatc attcttaata gtgtggacta tactactaat attgtttatg gtatttaata
    20581 ttccactagg acctggaata cttccttcat atagcatgta atttatttaa atctttctaa
    20641 aaggagaaat aatttatgtt agataaaaat agacttataa ataattttat ggatatggtt
    20701 agaattgata gcccatctaa tcaagaatta gaaatgtcta agtggttggt aaactactta
    20761 aaagaaagaa atatagatgc cattatagat gatgcaggtg aaaaatatgg tggtaataca
    20821 ggtaatgtca ttgcctatat aaaaggtgaa gaaggaagta gaccactttg tttatgtgca
    20881 cacatggacc aagttcaacc ttgtttaggt gtaaaaccaa tactagatgg taatgtagtt
    20941 agaagtgatg gaactactac acttggtgca gatgataaag ctggaatagc tgctatactt
    21001 gaagctttag aacatgttat tacagaaaaa ataccacata gagatattta tctttgtttt
    21061 acaatctgtg aggaagctgg tatgcatggt gtcaaaaact ttaatcctga caacttgcct
    21121 tgtaaagata tggtgatttt agattctggt ggagctattg gttcgatagc atacaaagct
    21181 cctgctcaac aatctataaa aatctctttt caaggaaaga aagcacatgc tggtatagaa
    21241 cctgaaaaag ggttaaatgc tatattagta gcctctcatg caataagcaa catgcacata
    21301 ggcagaatag attcattgac tacttcaaat ataggtgaaa tagaaggtgg tggagctaca
    21361 aacatagtaa ctgataaggt tacattgact gctgaaatta ggtctcatat acctgaaact
    21421 ttagagtatg agcttaatca tatggaaaaa tgttgtaagg acgctgcatc taaatttaat
    21481 actacttata cttttgaaca taatatgtct taccctagtt ttgaacttag tagagatagt
    21541 catgttttca agttaagtga agaagcaata agacaagttg gtgttgttcc aaatccaatg
    21601 gtaattggtg gtggaagtga cgcaaatata ttagctaatc ttggatataa ttgtgctata
    21661 ttaagtctag gtatgtatga tgtacacaca gttaatgaat atgtaaatat agacgaatta
    21721 tatgatactg ccaaaatagt ttatcatatg attaaattat aaatatcata atagaactct
    21781 ttaaattata aaaataaaaa cctatgtatc ctcaacttta taagttatat attagagttg
    21841 ttttacatag gttttagtat ttttatataa taatttgttt taacattttt cataataagc
    21901 tttgatattt tatatagtaa tttgttctaa catttttcat aataagcttc aatattttgc
    21961 ataataattt attctagcat ttttaataat aggctctagt attttatatt aataatttat
    22021 tctagtattt tacataatta tttgttctaa tttttttcat aataagcttt aatactttat
    22081 atagtaattt gttgtagaat tttatacaat ataatgattt atacagtttt ataaaatatc
    22141 ttaaaacagt atttcagtaa tattttttgg tcttcctcca ccaatactag tctcttttgc
    22201 acatattcga cctaaacctg catttactat tttatttaat atacgtcttg cacttctttc
    22261 acttacattt agatactctg ctaactcttt tgaatcataa atcttacttt ttctattctc
    22321 atttatagca ataatttttg caactgactc acaactcatt ccagtctttt tagatatttc
    22381 gattaccttt tcatcagata gcatcaaaga ataatttaat tcattttcgg aagctaaagg
    22441 tcctcttatg ttttcatctt catctaccaa atatatacca atttcttttg aatctatgga
    22501 gtgtcttaat gctttatgtg cattattttc agcctgatac gcagttactc cagtaccaat
    22561 tcctatacta agagaaaagc ccatgtcttt tatctctctc tttagattga atagcttatc
    22621 ataattatac tcattatcag ctaccccttt atgaacaaat acaacataat catttcttcc
    22681 aagtaaaaat aaggaacctt gaatgcttct tacatagttt actacaagct tatccatatc
    22741 tgattttttt atcatgtcag aataatagtt atctatcttc tctttataat ctattaaact
    22801 caatatttca acagcaattt gagaaaatct tgccttactt agagcatatt cactctttac
    22861 cttgtcataa ctttctttga ttaattgtat agtagcttgt aaacgaaata caggatagcc
    22921 tctttctttt aattcattat atactgcacc aaaaccagtt aacattatat ccgtcttatt
    22981 ttcttcaaat aattttatat gccattctac aagttcagac tctcctactt ccaaagaaaa
    23041 tggattacaa aatacactcg ttgctttaat atcaaattct ttaagtgcat cttccacaac
    23101 atatctatca actacatcta tactgaattt atctaatttt atatttgcac tttttattgc
    23161 ccaaaatgcc ttcattatac tcgtcccact tctcggtaca aatgaatgtg gcttacttat
    23221 ctcatactta gattttataa attcataaac tgcacatcct gtaaatataa tagcatcaca
    23281 ttcgtcttca catttagaaa taacttctat tgtatctact actttttctc ttacatatat
    23341 tttagtcttt aaatcactgt ctatctgttt taaatcatcc tttatcttaa acccagagtc
    23401 tgaaggacct ataataccca ctatcataaa cttcgctcct aatccataaa tattatactt
    23461 tttaaaaatt atatcctcac tattttctac ttctatttaa ttattttgaa ctaatccatc
    23521 ctacctacat ttagaatgga ataattagct tatttttgat aaagtaactt ctcaaaatca
    23581 gcacttggaa taggcttaca ataataataa ccttgaatta ccacacaatc taaactcact
    23641 aaaaattcag cttgttcttt tgtctctaca ccttctgcca ctacatccat atctaaatct
    23701 tttgccatgg ctatagtgtg ctttaaaact attttttctc tgtctgtgat tccttcctca
    23761 ttaaagaaac cacaatctat ctttaatgta tcaatattaa tattttttaa catatttaat
    23821 gaagaatatg ctgaaccaaa gtcatccata tttaaaacaa taccatccat tctaaggtcg
    23881 gctattatct tagtaaataa ttttatattt ttaataaata aactttctgt aagctctaat
    23941 tctaaaaaag attttggtat actatattta tttattaaac ttaaaacaat ttctttaaaa
    24001 tgtggattat gcaaatgtaa tcttgataca tttacagaga taggaactgg ctcttcacct
    24061 aaatctatcc attttctaat caaagaacat acttgttccc atacatacat atctaatctg
    24121 ataataaacc cattcttctc aaatagtgaa ataaatttaa ttggaggtat tatacctttt
    24181 tctggatgaa cccatctaac caatgcttct gcaccaacaa ttttatttgc attaagatta
    24241 tacttaggtt gtaaatatac atggaattgc ccattttcaa gtgcgtattc catttccctt
    24301 tccatctgtt tttcttcaag tgcatcattt cttatagtat catcataaaa tatatagttg
    24361 ttgatacttt gtttctttac ttttttgtga gcatatcctg ccatttcaca cgcatttgta
    24421 attggaatat gattatccaa aattctataa actccaaaac atggtactaa catatattca
    24481 aatttttttc tatttaagct atttttaatc ttataaatta ccttatgaat atctctatca
    24541 gagtaactct cataaaaaat gcaaaataca tctgcataca tacgacaaca tataccatta
    24601 gaaccaatgt ttttttgaat caactctgca acatatatta aagctttatc tcctcctcta
    24661 actccataaa tgtcattaat taccttgaac ttatctatat ccatcattat aattgcataa
    24721 cgcttgtcag gatatctttt aagcattaaa cttatttgtt cacaaaaact ttcataattg
    24781 tatagtcctg ttaatgtatc tttttggttt ttatgtagtt gcataagata atctatattt
    24841 tttatagcaa ctaaaatatg tgtttgtttc tcacctaact tatttttact actaatcttt
    24901 aacatataaa ttaatgccca atagtacttt ttatctattc ctaaacgtct atactcaaaa
    24961 tttagttcta aatcgtcttg cttgctatta ttaagactag caagagattt tagaaggtgg
    25021 ttatcattaa ataatattat atcatcagga tgaattaaat gtttttttat gtatgaaaaa
    25081 gttttttcaa gattttcctt tataggaaaa ctaaaaatat tgctctctga ttgataaatt
    25141 ggagtaatta aattcgtatc aatgcaaata gataaaatta tatcatatgt attataagct
    25201 aatttttcat aagccttaga ataccctttt atcattaaat catcaaaata aaccttatca
    25261 actaactctt tatgtttaaa taaaatatta ttcgtcgaat cagctaagtc actaattact
    25321 ttcatttcat tatttctaag tttgttctta ttataatacc tcttcttatc ttggtacatt
    25381 ctctcatcag caactttaat tagcttatgt atatcaatat tatcgtcact ccaaatactg
    25441 cccactgcta cactatatat catctcatcc ttaaattctt cacttaacca actcactaat
    25501 tcttcaaata gttgttttga tatatcttca cataatacaa caaactcatc tcctccaata
    25561 cggtaaacat tataagaatg aaagtatttt tttattatta cacatgctga cacaatagca
    25621 gagtcgccat tagcatgtcc aaagttatca ttaatatctt ttaacccatt tatatctaca
    25681 aatacaactc ctatggattt aacttttcct ttttgaaaat tatctatata cttaatatat
    25741 ttatttctat tatatgcacc agtcaagaag tcatagtagc tcatataatt taatttattt
    25801 tctacttttc tttttttcat ctcagttaat aaaaaataag atagggatgt caaaagagag
    25861 gtatctccaa cagctttatg tggattatca actccaataa accctactac tttatcatct
    25921 tgttttagtg aagatgtcat taaactttca attttttgag gttttaaaat ttcatattct
    25981 attggctgtt cttcttttat attttctata tcatcaatta ttacaaaacc tttttgttcg
    26041 aataataaaa accaattctt taattcatta atatcaagat ttgttagtgc ctgtttttgt
    26101 tcatcaacac cttcattgca ccattcatat gtattagtta ctttttttct atcttctgat
    26161 acttcaaaaa catatgctct atcagcttta tgaaatttac caatattggt taatacaaga
    26221 tttacagcat cagaaaaatt agattctgtt ataagatgtt taatacatcc aactaataac
    26281 tcctttatct ctaatttttc tgctattgac ttacttatat cttctttttc tgtaatatca
    26341 agagctattt ctaatcgtgc atgtttgccc tcccatttaa ttaacttgtc ctttaatata
    26401 aaatgtctat ttgttcgagt attcgtattt tcccatatgt aatattcatc ttcttttaaa
    26461 atagagtttg tacaaaattc gcagggagaa tctttcccct gtaatgcttt ataacatttt
    26521 aaatgggata tatcattaag tcccattgcc tttttaccaa tttcattaat atataaaagt
    26581 tcatatgtat ctaaagaaga aacatataca atttcatcca actcatctat taaatttatt
    26641 acatccattt atatatatct ccttttattc attttccaga ttgaattttt aaagctttta
    26701 aaattttgct atatatttgg caatgatatt atacttcttt atgttttaaa atagtacctt
    26761 aatgaggttc tattttttag taaatagaat tattattgtg tcaatcgtac aatagagttt
    26821 tgtaatacct aatttaatat atttataatt aattatctca ttatgtgttt ataattaatt
    26881 ctcatataaa tgacaaatct ccacctcaat taagtattcc aatcatatat gaagataata
    26941 cttcattcat ttaaaaatat aaaactatta tatattaaaa tttcttcaat aataaattat
    27001 ctagattgtt actttgatat attatataat atcacaaagg ctgatataaa aagacaaaaa
    27061 gggcaatttt tttatatcaa aaaaaaatgt taaattgata ttatccatat ataaattgat
    27121 attatccata tagatgctat atttaacaat tctacttact tcccttacac ttattagcat
    27181 atagttatta agagtttgtt gcaaaacaac acttagcaca ctttaaaaag tgtggtctaa
    27241 taagtaatca acgaagaaga cataataaag cataaaatat gatatacttt tccacgccat
    27301 caaaactgag gattttatta ttaatatatg ctaaaatatg cttaataaat taaattttaa
    27361 tgggagaata gttatgaaaa tatttagttt cttgttgttt gtgataggaa tatgtttatg
    27421 tattgctgga tttataggac attacccagt atttgttggt acaacattga gttttcttgc
    27481 aattgcaatg atagctgtaa gacaagtcaa aactaagaaa aaaatgaaat aggcaaatcc
    27541 taactttaca agttaatatt acataagtaa ttagtctaaa attggatact ttttctatta
    27601 cagaaataca tcatccactt tgtattttct taaaaaaata aaatagctat gtaaattcaa
    27661 gattagatag attaactctc tatccatttc attgtaaaat atacatagct atttgtattc
    27721 gatttaaaat acttagattt tcttacataa caaataattt ctatctgatt attactcata
    27781 ttcatttagt aatcactcag caactaatca tttagtatct attcatccgc catacggtaa
    27841 cctaccccaa cctcagtcaa aatatattct ggctgagcag gattcttttc aattttcctt
    27901 cttatacttg ccataaaaac tctaagcgac tgattttcac tttcatagta atttccccaa
    27961 actttatcta ttataaactt atgggttaag actcttcctg aatacttaga catcaactca
    28021 ataatcttat attcgattgg agttaaatgt atttcttcac cattaattga cacaatatga
    28081 ttttcataat ctatctttag gtttttaact tcaaaagact ttggagcatc attatttata
    28141 ttatcctgtt gagctttatt tctaagagcc acacgtactc tagccaaaag ctctgttaca
    28201 ctaaaaggtt tagttaaata atcgtctgct cctccatcta aagcttccac cttatccctc
    28261 tcatgctctc tcgctgaaac aacaattatt ttattagtct ttgcacatgc cctaactcgt
    28321 cctattacct caatcccatc aatatctggt agtcctaaat ccaaaattat caaatctggg
    28381 tcaagagaat gtataagtga tatagctgtt cctccattat ctgtctctac acacctatag
    28441 ttttgagttt caagagatac ttttataaat ttacaaattg gcttatcatc ttctacaatt
    28501 agaactaatg gctttatttc cacttgtctt tcccctcctc atcatacata ggtatgctaa
    28561 atctaaatgt agctcctcca gaaggattat taaaggcgac aatttctcca ccatgagctt
    28621 ctactataga tttacatatc tccaatccaa gaccaatacc tcttctttca agatttctag
    28681 acttattctt agtataaaac ctattaaaaa tattcccgat atcttcattt ggtattcctt
    28741 ttccattgtc tgcaacttca aatagtactt gatttgactc tttttttaca gttagttcta
    28801 tcttagaatt tttaggtgta tgccttatag cattatcaat tagatttact aacacttgtt
    28861 ctattaataa tacatccaca tgaacgatta ttatctcatc cggaatattt gtttttatgt
    28921 ctctactatt ggcaaacttt ttgactctta atatagattc agctattatt tcatcaacaa
    28981 cctctggtcg tttttcaata tccaattttc cttcatctat tctggtcata ctaagtatat
    29041 tctcaacaga atgagttagc caactcgtat cttcatatat atttttcaat aattctactc
    29101 tagtttcttt atctatcaca tcatcatttt caagtattgt tgaagatgaa cccaatatac
    29161 ttgtaagtgg agttcttaaa tcatgagaaa ttgacctaag caagtttcct cttaacctct
    29221 ctctctctgc ctcaagattt gcttttttat ttttctcaaa taaattttct ctatcaattg
    29281 ccaacgcaac ctgtgttgaa actgcttcta atagtatctt ttcattttct gtaataatat
    29341 ctatcttaaa acacgcaaca cctataacac caagaacatt tgattcttga ccttttatag
    29401 ggaaataata tgcactgctg tttttacaat attttgtccc aattccaact gggttacctg
    29461 tcctaaaagc ttcttttata gcttcctttt ctaatactga atggaatata ttctcacttc
    29521 catcattgtt acaaatataa atacttggct tacctagatt attattctca tctgcaatag
    29581 tcactattac agttctattt aatatattta ctaaattaga cccacaaaat tcaataattt
    29641 gatttttatt ttttgcttta agcaacgttt tgttattctc atagagcaat cttatcattt
    29701 tttctctctt atgagaaagt ctcacttctc tttttatcct agaagttaaa gtacttgtta
    29761 taattgctgc cattagcata atacaaaagg tcataggata atcttttcta taagctaaaa
    29821 aagtatataa tggatgcgta aagaaaaaat taaatgatag cactcctatt actgaagaaa
    29881 gtattccaaa aaaatatcca taggttatac ttgtagcaaa tagtacacct aatatgtata
    29941 ctagtataat attagattca ttaaaaccta ccttttcaaa aactactgat attccagtag
    30001 caattgtcat aaccaatata gtttttatga agtccttaat aattatcttt ttactgagat
    30061 agccatcttc atcataatca tactctttta agtcttcatg ttgtagtcgt tcctttttca
    30121 tttactacaa ttcctcctta ttgttactgt ttaaattggc tctattttat ataatacaat
    30181 tttatcataa taaattcaat caatacattt aattaatgta cttaaattac taaaaggtgc
    30241 tgtcttaaaa tgaaaataaa tctctatttc aaaacagcac ctatatattt aaattactaa
    30301 tttagttttt acatacttaa atcaatagtt ttattcaatt tcataaatta taatacttca
    30361 attataaaac atttctatcc aacaagcata aatataaagt gggcacatat acctgcacat
    30421 aaaccaccta tagtatgcga aagtatcgct ttaccagcca atggtcttgc atctaaagca
    30481 tccatcatac ctatgtgtgt acttaaatat ccactccaac acatacccat tgctgtgaat
    30541 actgctatat cattaggagt tatagcgcct gattttataa actctggtac taaagatatt
    30601 gctgctccaa cagctcctaa tgcagttaca gggaatgcta ttgcctctgg tgatgtgaat
    30661 ccaaataatg gttctattat gaagctaatc ttatcaccaa tagcaggtaa taattttata
    30721 ccttcatatg cagctcctgt gtaaacagct tgacctgtag cagggtctgt agatggtcca
    30781 aaagttaata acataactaa tgtacaaact actaaaactc ctggtattat agccataccc
    30841 atttcaacac ctaacttacc accttcaagt atagcatcca atgttctttg gaatacatta
    30901 ccatctctta tttctctaaa ctcttcaagt tttgcacctt tatcatttat ttgcttttca
    30961 gtatcatttt tagggtcata attataatac tttttagtaa aagtcaacat aattctaaca
    31021 ctaataatac tacctattat tgccgcaaca ttacctatta tagctggtag tacatattct
    31081 ttaccttgag ctatcataaa agttgttaca ataagtccca taccaaaggc tgttcctaaa
    31141 ttacataaag caggtacttg atacttctta aaatattgtg taaatgtttt gtctttagca
    31201 aatggtataa tagctggatt atcagataaa tatgttgcaa ctactcctgc tatactagca
    31261 ccaggtaagc cccatatagg tctcataaga cccttaaata tcttattaac taaagatatt
    31321 actccaaact ctgaaagcaa tgcactaagt gcacctgcaa gaactgccat agccattatt
    31381 aaaaatactg tgtctaataa aagcgcatgt gctgtactca ttattacttt aaacatcatt
    31441 cctgcaccca tgatgcttcc tacatatcca aatcctaccg ccaatagtac aataaatacg
    31501 aaggtttcca tacttactgc cttgactctt ctcttatccg acagcttttc catcttgaaa
    31561 tcttccccct tttaatttta aattaaggtt cctaacattg gtacaaattt tttggtacaa
    31621 actgagttct aaaacttaca ctcgtaatgc aagttgtcag ttttttgaaa taaaaaaaaa
    31681 ttacgtttat agaataagaa tatcctcttt aatttggata ctcttattct attttatgtt
    31741 attatattat catccttttg tttaaaagtc aattttttct atttttgttg tttaatttta
    31801 tttatactct ttttatattt ttcattttct tttatctttg taagtactcc atataagttg
    31861 acttttctaa atacagtagt tataaatacc aatcctaatg caattgaact tgcacacgat
    31921 aatgtactca ccccatattc tacagctttt atataattat tggtcaaaac agaatacata
    31981 gtattatata ttccataacc tggtactaat attattaaac agcaaacact taatgtagtt
    32041 gctggagtca tataaattct tgcacataac tcacaatata tcgcaaaaca aactgtagct
    32101 ataaaaaaac ataagttttc tgttactccc atatttaaaa gaaatttata cgaaaaccaa
    32161 gctatacttc cacctattcc tgctagtatt aagttttttc ctttcatatt aaatagcact
    32221 ccaaagctta aggcagtaaa aaaagctgct attacttcta taaacaaatg cacttatatc
    32281 ccccctaact tgaagtacaa tccaagtacc aagaacattc ctactgctat agatacacct
    32341 acaaaaaata cttctgctaa ttttgcaaga ccagaaatca actgtccatc taataaatct
    32401 cttaatgcat tagtcaaagc aagcccggga actaagagca ttattgctcc tgctattaaa
    32461 tggtctaacg tctttatgaa tccgagcttt aaaattaaaa ttgaacaaga agctataata
    32521 actgctccaa ttgcatttac aaaaaagtca ttaagggaag atttacttaa atacataata
    32581 acaaacttag tcagaatccc aacagtaaat gcagctataa attcttccac atttcctcca
    32641 aataatatcg aaaaagttgc tgctgcaata cctgcaaaaa atattgttat taaatccgag
    32701 taatagttat cttcacttat ttcatctaaa attttctcac ataattcaat atctaaatta
    32761 tttatactta ttgctcttga taatgagtta acttcatgaa ccaagtttag gtctactctt
    32821 cttgagctta ttcttttaat tgctgaatgt aatttcccat ctacaaatac agatgccatt
    32881 acagctgttg gagttgcaaa tacatctacg tgatctattc caaaagattg acatattcta
    32941 gctatcgttt cttcaactct ataggtttct cctccacttt gcaacatagc tttacctgca
    33001 tttgaggaaa agtttaaaat tctatctata tccacaaaac atatctccca ttcttttata
    33061 gtattattca tattttaata caagatatta tttatttaaa ctattttaaa taattcatat
    33121 ccaatattta cattttatga aaaaacttgt tttttatgct tgtcaaaatc aaattttaag
    33181 cttgtttaca ccataaaatg gctgaattaa tatttgacaa acactttcaa ccatttatat
    33241 aaccttctaa attgtataac tttttactac aaataaaatt atatctcttt taattctttc
    33301 tcttgagtat ttagcttata gtaacttcat atttatatat gtacaatata aaacattatt
    33361 tttatgatac aaaatataat ttgtaaatgt atatatgtat taactgtgta tatataaatt
    33421 attcttaacc ttatcagttt tttcatatat cttcatctat accgaccata tattaataaa
    33481 tgatattaca tagacttaag tacattaaaa aacttaaatt tagttattta acaacataat
    33541 actctaattt aatctataaa aatccatacc taatataatg caactcttat tttaacacca
    33601 tctattacac aaaacaacat attaaaaagt aaaatacaaa atatccacta taaaccttat
    33661 tttaatactg aatatatatt ataatatatt taatgtagct taaatatagt ttaaacataa
    33721 agaaaggaaa cggtatatgc taagaaaaga taaagttcta ttatctctac ataaattatg
    33781 tgaaaatatg actttaaaag accttcaatc agataaaaca ggattcacta caatagaaat
    33841 tgctaaccat tcatctcttg atagaagtaa taccagtaaa gaattaaata acctatacaa
    33901 tgaaaaaaaa gttctgaaaa tatctggtaa gccaatttta tttctacatg ctagtattat
    33961 agaaaattta attggccgta ctttgaacag tgatgaattt tctataaata attgtaatga
    34021 gctacttaaa tcaagtaaaa atgactcaga agatattttt tcaacattac ttggacatga
    34081 ttctagtctt aaactaccta tagaaaaagc taaatctgct atactctatc ctccaaaagg
    34141 tcttaatacg ttactaatag gacctactgg tgttggaaaa agtacatttg ctgaaacaat
    34201 gtacaaatat gctgtagaaa gtaaaatctt ttcttctgaa agcaaattcg tagtatttaa
    34261 ctgtgctgaa tatgcagaaa atgctaactt attattaagt aatttatttg gttatgtcaa
    34321 aggttctttt actggtgcta ataaggataa attcggcata gttgcacagg ctgatggagg
    34381 catattattc ttagatgaaa tacacagatt accaccagaa ggtcaagaga tgctttttct
    34441 tttgatggac aaaggcatat acagacgatt aggagaatct gacattgtgc ataaagctaa
    34501 tgtctttatt gtgtgtgcca caacagaaga tatacattct tctctgcttg ggactttttt
    34561 aagaagaatc cctgttacaa tcaacctacc tgctttacag gataggtctt taaaagaaag
    34621 attatctctt attaaatact tctttattat agaatcaaaa tacaccaatg caactataaa
    34681 agttcacaaa gatgtaatta aatcattact cctttatgat tgttttggta atataggtca
    34741 gcttaaatct gacatacaac ttatgagtgc aagagcattc ttaaattaca aaactggact
    34801 taaggataat atagaaatag atttatccat tgttcctgat tacatctata ttggtctttt
    34861 aaaattgaat gaaaatcgta gtaatctaaa taaattatca gaacttgatt atatgctttt
    34921 ttatgaattt aatggtaata acttagaagt tgaatataca aaagaactat ctaaatacaa
    34981 tatagataca tcaaacaatg gatttaaata ctctacagag attccttatc tggaaaatga
    35041 tataaggagt atgtttataa attacatgga aaagtactct acaaaattac tttcgatatc
    35101 ttcagtaact cattctgatt atacaagtaa tgagattttt aaagtaatca atccaaagat
    35161 ttactatgct gttgaacatt ctttaaaaga ggctgaaaaa atatcgagaa acaaatacac
    35221 aaaacaaact tatattgctc tttcaatgca tataagtgca cttatagaaa atataaatca
    35281 agacacatat aatcctaagt acaatttata taatgataaa attttcttag ataaagattt
    35341 aaatatagct aaaatagttt taagtataat tgaaaatgac ttacaaacat ctttacctaa
    35401 agatgaagta aaatttatat ccatgtttct aaatagcatg tatcttgaac caaacaatca
    35461 atctgaaagt ataggagtca taatacttgc tcatggaaat tcaacagcaa gcagtatgtg
    35521 tgatgtagca aattcattgc ttggtacaaa ccattgtaat gcaattgaca tgcctcttga
    35581 tgtaaaagta agtaccatac ttgataaaac tatagagttg gtaaaagaat gtgacgaagg
    35641 taagggtgta cttcttttaa cagatatggg ctctcttata gcttttggag aacttatttc
    35701 agaaaaaaca aaaatcaaaa ctcgctcaat tgaaatggta tctactccaa tagttttaga
    35761 agcagtaaga aaaagtacac taccagaaat gactttggat gaattagcta attccttaag
    35821 ctctttaaat ccatatattg gacgagcagc aatcgattca acagaaataa actatcctga
    35881 aaagtcaaga gagtatgtaa taataactac ttgtataaca ggatatggtt cagctatgaa
    35941 agtagcagac tttataaatt cttcacttaa aaatattagt aaatacaata ttaatttagt
    36001 tcctcataat atagaaagtt ttaaaatgta taagaataaa tttagtaata ctaaaattct
    36061 ggcagttgtt ggaagtgtag attttaatgt agccaacacc ccttttatac acatagagga
    36121 actactaaat ggatatggcc tagatatgct aaacaaaata atagaaggta cattcaatgc
    36181 caatagtatt acaaatataa aagaaacaaa tctatcatac aacagtttaa taataaactt
    36241 tatgacccaa aacttagagc ttttggactc tgttaaatta ttcaactatg tcaattcttc
    36301 cttatttaca ataatagaat taatagatga aaacttaaag agcaaattta agctaggata
    36361 tatactacat tgctctttta tgatagaaag atgttttaaa aatacaactt ttccatataa
    36421 taacattact gaattaatta gtaaaaatca tgaactatat agtttaatac gtgaagcctt
    36481 taagccaaca gaagcttatt ttaatatttt gataccagac gaagaaattg cttatataat
    36541 agacatgatt aatgagtatc taaataaata aaatttatag cacttatttt gtgcatatta
    36601 attaatatat gaaatggagg acgagatttt gaaaggaaaa ataaaacagt taacaatact
    36661 tgcattaatt tttatattta taactcctgt atttgcattt gcagatactc caccagtacc
    36721 aaattcttca agagcagcac tacttataga ccaggaaact aaaagaatat tatttgaaaa
    36781 aaacattgat gaaaaaatgc cattagcgag tttaagtaaa atgatgacct ttttattggc
    36841 aatagaagca gttgataaaa atcaagttaa agagactgat atggtgaaaa tagacaagtc
    36901 tacagcttca gtaggaggtt ctacttgtaa acttaaagat ggtgatgaaa tatctctagg
    36961 agagcttatg cagggtctaa tgctagtatc tggaaatgat gctgctatag ccatagctaa
    37021 acatattggt aaaactgaaa agaattttgt aaatatgatg aacaagaaag cagaagaaat
    37081 aggaatgatt gatacgtatt attttaatcc aaatgggctt cctatatata ctgacccaga
    37141 acataaagaa cctcctattg aaaatatgtc aactgctcac gatatagtta cacttggaaa
    37201 gtatatgtac gaccattatg aaaatcaagt tacaagaata accactatgc aagtatataa
    37261 tgatactaaa aaggatttta cacattataa cacaaatcct ctgcttgttt cagtacctgg
    37321 tgttgatgga ataaagacag gatatacaga taatgctgga tattgccttg cattttctat
    37381 gatggtacct aaagatgcta aaaacgaaag aaatcataga ttgataggtg ttgtacttgg
    37441 tgatggtaac aagaaaaata gaatttcttc ttccgctact ttattgaaat atggtaaaga
    37501 taatttccat tctaaaaaga tagcacataa gggtgatatt atagagactc cttgtgttga
    37561 tggtattgat gattttaaga taacagttaa ggttgataaa gatttgtatg gtgttgtttc
    37621 agataacgag aatatcaatc ctaaggtagt gtttaaaaat atgaattatc ctatccataa
    37681 gggagatatt gttggtgttg caaagtatta taatgactct ggtaaatttg ttggaagtgt
    37741 tgatgtaaaa agtgaaagta atataggatg tattcctttg aaggataaga ttaagattaa
    37801 ggttgctaag ataaataaaa aacttgagat taaaaattct gtttgtttta aagcatagta
    37861 aagcatatta ttaaaagggt atgttaaatt tataaagact ccactttgtg gagtcttttt
    37921 gttttttaca aaaaattaaa atagtggcaa caattgagga tgtgagggag agttgccact
    37981 attttgtata gggtattata ttatgttttt aagctagttt tactatcttc tatgtttata
    38041 taataactct tgtgtgtgaa tttaattgat aattcatatg aaaattatgt gaagttttga
    38101 tttatttgta atatattcta ctactattat aatttttcta ctggatatac taatcatttg
    38161 tttaacatta tctgagattg atttgcaaac ttttatataa ctaaattagt tatataactt
    38221 atagattcca ttaaataccc taataatcat atatgtacat acaaagtcat gcttatgcaa
    38281 aatctgcagt ttcaactaac ttattatata aaccatcttt atgtagaagt tcagcatcat
    38341 ttccagattc tattactcta cctttatcta atacatatat attatcagca ctcttaattg
    38401 ttgaaagtct atgagctatt ataataacta tcttatcttg tatgtactct ttcaagttgt
    38461 tcaatatctc tttttgtgaa atattatcta gagctgaagt tgcttcgtcc agaataagta
    38521 cctttttatt acttactaaa gctctagcta ttgatatacg ttgtttttga cctcctgata
    38581 ttttgacacc tttttctcct actacttcgt ccaatccctt atctagattt tttataaaat
    38641 catctaaaca agtaacttct aatatctcat ctaattcttt atcacttatt ttattattta
    38701 atactatatt attttttatt gtgtcatcaa atacaaattg atcttgagtt actatatcaa
    38761 tattatttct tagtgatttt aaattaatat cctttatatt aacaccatct attaatatat
    38821 caccttcatt tatatcccaa agtcggtata ttagatttgt tattgttgat ttgccacatc
    38881 cacttccacc aacaattcct gttacttccc ctttctcaaa ttgtaaattt atatcattta
    38941 aaacaaggtt taaatcctca ccatatctaa aagatacatt tttaaaatct attttcttaa
    39001 tttcactgtt atctattcta tatccattat tatcaacttt aatatctatc ttttcatcta
    39061 ttactgaaaa tactctattg atagacactt ttgattgtgc tattctagta ttcgccctta
    39121 ctatagctat acatggtcca attaacattc ctgtatattg ttgaaatgct attaactccc
    39181 ccatcgtcat cttattattt attattttat atcccccaat tccatatatt aatattgtta
    39241 tcaatcctgt tagtatttga gatattgcta tattactact cataatgatg ttcaaattca
    39301 aatctttttt tatcaaatct ctctctctct ttaaatactt attaaagaaa ttcttttttg
    39361 aatttaatat aacaatatcc ataatattag atacgtactc ttgaatcaaa tttgataaac
    39421 tgcctgaatc acttcttatt tcagaaattt tcttagatat aagttttgtc attttatttt
    39481 gagaaaatgt taatatcaac tgtaaaaata aaactactaa aaataaatca aactgcaaat
    39541 taattaagaa aattaacgat attatagctg taaacacatt tacaataata tcaaatataa
    39601 tctctgctcc aaagttttct atcataaata tatcactttc cataatggat aaaatattac
    39661 ctgttttctt acttgaataa tatctaccag aaagttttga tatatggtta agcaacttta
    39721 cttttagatt tatagtaact ttatttttta ttgaagtata taaatatgat aatataacat
    39781 caaatgtagc tgataatatc cttataaaaa tatatatcaa tattaaattt ataagcagaa
    39841 aaatattttt atttcctatt ccatcatcta ttatacatct aattagttga ggtattacaa
    39901 tatttacgcc agcaattata aaaaccatta taaatgatac tatcaactta gtcttattct
    39961 tatatactat tatatttagt attctaaata aattattatt aatagttttt ttcatctatt
    40021 tttccatctt ttatagttat aattctatca gctgtctttg caatattatc attatgagtt
    40081 atcataacta gtgtttgttt gtactcttta acacaccatt caagcatatt cataacttca
    40141 tttgtagtct tactatctaa gttgccagta ggttcatctg caaatattac tgacggtcta
    40201 ttggctaaag ctctagctat tgcaactctt tgttgttgac ctcctgatag ttcattcgga
    40261 tatttcttta tttgtttttc aatccccaac ttattaatta atctcataac atattcttta
    40321 tcttcttttt tcccatcaag caacacagga agtactatat tatcatatac atttataact
    40381 ggtattaaat tgtaactttg aaatatgaag ccaaattcct gtcttcttat ttcagacagc
    40441 ttatcatcat ttaatgtata taaatctaca tcatctaagt acacattccc taaagttggc
    40501 ttgtctaagc ctgcaacaca gtgaagtagt gtacttttac cagaaccact tgcacctaca
    40561 atagctgtaa atttatgtgg ctctatatct aaatcaatac catcaagagc tctaacttca
    40621 ttctcatatt ttccatatat tttttttaaa tcttttacct taagtatttt cataacgtat
    40681 ctccattccc atttaaaaaa catatatttt taaattaaat tttcgtaaat aagatctact
    40741 gccatatcta aattctctaa ttgatataag tatacttctt tgtagtcaat actaatatta
    40801 aactctttat ttaaaatagt taaaaaatta tatgcattat aatttccaat acatgtaaaa
    40861 ttgttaaata aagaatattc acttacaaat tcaaagtcta tttttatttt agaaaagttt
    40921 ctatttatca catttattat tttccttgct atatccaatc ttatcaaatt agatttataa
    40981 cttggagtgt tcaagttttc tatttttaaa tcttctttac ttttgctttt ttgaataagt
    41041 atttcttcca attcattaaa cttaatatat ggattgtttt ttaatatatt tgcaacaatg
    41101 ccagttgcca ctgcacaagc cttactattt ttaccaaaat gagttacttt atctttaaat
    41161 ttaataaaat tatcttttga atttgcatac atttgaatct tattttctgg ttcgtatata
    41221 tattgattat ttttatatat attttcatta cctactacac caataacact ttcaaatata
    41281 gtaggaatac tttctttatc ttcatattta ttatgttttg aacaaataat aaatctacct
    41341 tgactattta aaatattaca aaccttttct aattcttttt catacatact attaatagat
    41401 gcagctgaaa tgtttattat ctgtatatcc gacatagtca acttgctcag tgtactaaga
    41461 agatttaaag aacttgtttt tccagaatca ttaaatatat taataggata aatttgggta
    41521 tttttactta tatttaatat ggttttcgat acaaaagttc catgtccatt tatgtcattt
    41581 atttccttcc cccccaaatc tttcaattga aaatttgaat cataaacata atttccatta
    41641 atatcatcat catttacatc taatcctgtg tctaagactg ctattcttac tttagtcaat
    41701 taataatcac ctctaaaata aattaccttg aatataaaac taatccttac cataatatag
    41761 gttccaagat gtttttcatt tttttacaat ttgcatcaaa catttttttg ttatttttta
    41821 aagtatatat tttcgatgga caagttgtac aaaataaatt tactttacat tctttacaac
    41881 tctcaatatt tactggtttt aatttatcaa atatattaaa tatatccatt tctctattaa
    41941 gaatcctctc taatatgttt tcattaaatt ctaatatatt gaatatcttt aaatccttat
    42001 actctaagtt tggacacgga tatacatctc ctttatgatc tatacttatc tgattaacac
    42061 ctgctttaca catatttgaa cataaactac tttcatccac ataatcatct ttgcaaatgt
    42121 aatcaatatc aagtttatca ttaagatatt tgctatagtt ctcattacct ctaccaatat
    42181 tcataaaatt tcttattata ggcgttgtac ctaaatcttc atttaattta ttgaatttct
    42241 ctatgtcttt ctcattattc tttcctacca ccatagacaa acctacgttc tcgaattttt
    42301 ttagttttat aagtctaatc acatttaata ctttacagaa tactccttta cctcttactt
    42361 cactacaact taattcatca taaccatcta aactaatttc tattgcatat aaaccattaa
    42421 ttatatcatc aatctgtttt tctttaatta aagttgcatt tgtagacaga attattttac
    42481 ctttaaattt ttcttttata taatccaaca gctctaagaa atcatttctc atcaatggct
    42541 ctccacctgt aatggttaat atccttggat ttaatttaac tatattatct attacttttc
    42601 ttacttgaga tgtatctaaa taatcgttat tatctatttt agaatctaca cagcaataat
    42661 cacaacttag attacatcta ttagttggag aaaatgaaat tttgtttatt ctctctagtc
    42721 taaattcact tagaatagaa tcacttagaa gtcctatatg ctctaactta tctataactc
    42781 gttcataata ttttttatct tcattttctt ggaatacatc atacaaatta ccaagttgta
    42841 atgcattatc tactgaatac tttagaactt cataacattc tattggaatt ttaacccatc
    42901 ttccatttac tttattacta agaataactt gattattatt tattattttt tcacatatac
    42961 aatctaaaaa atatttgttt gagctattca tttattttat ttccttccta tatatttaaa
    43021 ttagaaattt cattaatttt cttttatacc acttactata ctaagtttat ttatcatttt
    43081 attagaaaaa taaactgcaa tgacacaaac aaaaacagat atagatccaa atattagaat
    43141 ttcatatatt ggaatttcaa atttaataga gttatttata ccatatacct gttgattaag
    43201 tttgttagtt tcagaaacta ttttataata attgaaacta gatataattc cagctacaat
    43261 catacttaat accccatata tcatattttc ttttattaac attcttttta catttttttt
    43321 ggacatccct attgctctaa atgtacatat ctcactcaac ctcacaatta tatttgatct
    43381 aactataaaa ataatgttta tagatgatat taataaaact ccaaatacac aaatcattgc
    43441 taatttatat gaggatttat tataatggtc tccaaaatga ttacgtacat atcttccctc
    43501 tatatctgaa aatccacttt tttctattat attatttatt tcttttatta cttttttatc
    43561 tgtttctttt tttatcttca caaaaacttt attataatca cttatccctg ttaattcttt
    43621 taaatccttt tcattaaata taatttgaat tccacctgat tgagattctc catcttgctc
    43681 tgatatatag ctatttttca ttattccagc gattcttact tttgtattta tatatttata
    43741 ctctccatct ttatatacag gaatttttat atctattaag tctcctattt taggtgattt
    43801 tataatctga gtattatttg acaatttaat tctagaataa aaattattta ccaataaaac
    43861 atttttataa tccctgtctg tataactata aacattttcg cctttatcta tatatttatc
    43921 tatattattt aatagctctt tattgtaacc tcgaattaaa actgtagact cattattatt
    43981 atttatttca gttcttttta gctcatctaa ataatcttct tctaagtcag catttcttag
    44041 atatcctttt aaataaatat tgggttcaac atctgttaca tcttcaatag cttttatttc
    44101 atttaataaa gaattatcat atttagaaaa tgtataattt gcatttattg gtgaatatcc
    44161 caaataaata tcaaaattgc catatgattt acttgttata ttagctgaat ctgactcttt
    44221 tccatatatg aattttgtag aagttagtct gcctataaat aaaaccccac atagtgatat
    44281 cgtaattatt attattattg atgtaacctt attcctaaat atatttttaa aagctatctc
    44341 atttataatt ccaacaactt ttttatgtga ttttaacaac aaaagcctag gaatataatt
    44401 taacttatct gtctttttta tagcatcaat tatagataaa tttccagctt tatatattgg
    44461 tactacagag gctaatataa ctgctataat tgacatgatg atagattcaa ttatagagtt
    44521 tgtatttata gttaattctg cacttttatc atatactatc atgagaccta agtaagaaaa
    44581 aactatacct ccaagtaaac caattactat acctacagat aaaactacaa tactctgaat
    44641 aaaaaatacc tgtctaatat ttctcttgct agctccaaca gctctaagta aaccaatttg
    44701 cttggtcata tctagtatta ttatgttaaa catattgtat attactaatg ttgcacataa
    44761 taaagggagt aagctttgct ttattgaata agttgttttt tttgaaatat ttttcatata
    44821 catagacata cttacttctg tatttggata aaattgatta cttgttaact tatattttct
    44881 ccctagattc actacttttt gagaatctaa atcttttgta ttcaatttta atgtacccat
    44941 atgagttatt aattcatatg gaacaatatc tttgccattg tttgaatatg taaaagctct
    45001 taccttatat ttatttaaat tttcatagta ttcatcagat ttacttaaaa taccaactat
    45061 tttaaattgc ttatctttac tataaataga attttcatta tttttattta tatgctcatt
    45121 aacaatctga aaatcaatag tttgatttaa tttgacatct aattccattt tgtctaaaac
    45181 tttttgttct attactaatt cattagaagt tctaggctct ctacctttaa ctaacttata
    45241 tctagtagaa tctaaaaaat ctttattgta agagcataaa tttagagatg ctccattatc
    45301 tttacttata atttctccaa atttaagtac atcattgaat tcttttatat cttcttcacc
    45361 attaagttct tttactatat cactatttat atcttcataa aaagcatgat aatctcccga
    45421 gtttttgtat gcatgattta tatctgattg tccttgagat tcattaataa cacttaatga
    45481 aaaaactagc ataacagcaa tccctatact aagtattaat gataaagttt ttcctttttg
    45541 tctctttaaa tatgacaccg caagtttaat atttatcata atcagaatcc tccttattca
    45601 tatttacaag aaaaactcta taacctaaaa tagtaggtta tagagcacta ttcattaaat
    45661 actaactaac tcgttgtgct agttaaattt aattattaaa aatactagag ttgagaaaat
    45721 cacatttcat ttgtaaaaaa ctacatctag tactttcaac atatttaata gactgattag
    45781 tattttttaa taagctactg ttccttttgg agttgatcct gcacaatcca ccatacagtc
    45841 tatttgtgaa attattccat gcttatcata ataccattta catggatctg cttgcacctc
    45901 aacatcttga agttctattt tttcttcgat tttttttata tgtatcataa tacatatccc
    45961 cctttacttt tgttttatat ttattataac tagttaaact agattataaa ctacatagtt
    46021 tttttgtcgt ttccacataa actctttcta atccacaata aattggtact gcactttgga
    46081 atttacctgt taccttttta ttgataagtt tacatctggt tgacatacaa taatcaagtc
    46141 tagtgcatcc atcacactct tcattcttag atatataaat ttttataagg ttcttaattt
    46201 ttttatcatc taatccatca tatatatttc ctagtaaaat atctttatct cctacacata
    46261 ctgtacatgg atatacatct cctctagtat ctattgcata actatttatc cctccaaaac
    46321 aatctccttt tttcttattt ataaattgtt tatctaaaat agatatatct atctcaggat
    46381 aatccttttt aatattcata attttactaa tttgttcatt taatatttta atatgagaat
    46441 tatcccaatt tttatccata aaatctgaaa ttggtgcgat atttttaaac ccttgttttg
    46501 ctatatcata tacactctca taaagatact taacagtatt tgagttatat gtcattcttg
    46561 ccctaacata tataccttta tctataagtc tttttccatt ttccattact ttttcataag
    46621 tacctactcc gttagcatct attctattta tatcatgtat attctttttt ccatcaatac
    46681 ttatcgatat gttttttaca ttctttgcta taaactctat tatttcatca tttataatag
    46741 ttccatttgt agttatatca aataatatct ttttgtcact caatctatct actaaatccc
    46801 tatgtatata tttaatcaaa tcaaaattta taaatggttc tcctccatgt aaaacaattg
    46861 ttgtataatc actattactt tctaattctt tattacaaat aaaatctatt gttttatcag
    46921 cagtttcata actcatattt tctttttttt tatcattacc ttcataacaa tatgtacatc
    46981 tcaaattgca gtcttcagtt acaaatatag taaatttcaa ttaacttttt catctcccca
    47041 tacagctgta tttaaattgt gtttcatcat actacaccat ctatccaatt ccaattcatt
    47101 atccttaact gaatctaata tcgctgggca atgccaacaa aaaatattta catcacaatc
    47161 tttacatttt tcaaagttat atggataaat actttctaat ttaatcaaag actttagatc
    47221 tcttgtttta ttttctttta taacttttac aaattcattg tcaaatatat ttcccatttt
    47281 atagtcatcc tttatcagtg aaggacaagg atatacatct ccatcataat ttataaatat
    47341 ttgagagttt cctgcattac atgcacaaca tcccattttt ttattttttt tatctttaca
    47401 catttttaat tcattatcta aaatatacgg aattgtaatt ggaagaactg tatcttcaat
    47461 taaatagctt tctttatttt ctaggcctct tcctgttgga ataaaatatc tttcaacaaa
    47521 ttctgttcca agctttttat ttaaatcttt aaattgttta tttaaatgag aatttttttg
    47581 tccaaatacc atagacagct ttatattact gaatccattg tcttttagca gattaacaga
    47641 gcttattact ttattaaata caccttttcc tcgtgtttca ctacaagtat tttcatctac
    47701 tccatcaata ctaatatcta ttttttcaaa attagttata ataaaatcaa cattatgttc
    47761 atctattaaa gttccatttg tggataatat taatttggta tcaggtaatt tttgttttat
    47821 atatttaatt atttcaaaaa aatcttctct tatcaatggt tctccaccag ttataattat
    47881 atgaggagta tttaaaactg atattatatc tacgatattt tttaaatcat atgtactaag
    47941 taaatctttc ttattagaag aagattcaac acaacaatgt ttacaaaata aattgcatct
    48001 atttgtcaaa caaaaataaa ttgcaacacc attgcttaac atatcaaagt ttaaattgtt
    48061 acttttaaaa atttgatttt tgttcataat atctataaga ttaataatat attttttgtc
    48121 actttcatca tcaaaataat ttacaaaatc ataaattttt attttattt
//
LOCUS       DAMKNB010000024        48093 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.025, whole genome shotgun sequence.
ACCESSION   DAMKNB010000024 DAMKNB010000000
VERSION     DAMKNB010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 48093)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 48093)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..48093
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.025"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            complement(229..1590)
                     /gene="rlmD"
                     /locus_tag="PC494_001529"
     CDS             complement(229..1590)
                     /gene="rlmD"
                     /locus_tag="PC494_001529"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HDF3912033.1"
                     /translation="MSVKKKDVIEFEVDKMEFGGTSLSQVGDRVIHMKGGISGQKVRA
                     GVKKVRSKKAEVKMIELLENSPLETEETCKHFRECGGCTLLSVPYEKQLEIKEKQVMD
                     LFLKQDLFGFQFLGIEGSPENKYYRNKMEYTFGDEVKNGPLTLGLHKKGKHIDIQTVE
                     ECMLVDEDFSKILVSSVEFFNEKKLPYYRTMNHKGYLRHLVVRKGIHTNEIMVNIVTS
                     SQEDFDMYEFKDMLLGIDLKAELVGVLHTINDGLADAVQCDELRVLYGRDYIQEEILG
                     LKFKISPFSFFQTNTKGAEVLYSIARDFIGDYNDKVVFDLYSGTGSIGQVMAGAAKKV
                     YGIEIVEEAVVAANENAKLNGLTNCEFIAGDVAKVVKDLKDKPDLIIVDPPRPGIHKD
                     AIRDICGFGAKEIVYISCNPKSLVVDLVDFKGYGYEIKMVKCMDMFPNTPHCETVVLL
                     RRK"
     gene            complement(1617..2339)
                     /locus_tag="PC494_001530"
     CDS             complement(1617..2339)
                     /locus_tag="PC494_001530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HDF3912034.1"
                     /translation="MAKKQRIDKILSNLGYGSRSEIKKYCKQGSVVVNGSEVSNPGTQ
                     VDTENDEILFNGEEVIYREYIYLMMNKPDGYISATTDKYDPTVLDLIDLSYLAFEPFP
                     VGRLDKDTEGLLVLTNDGKLSHRVLSPKKHVPKTYYAKIDGVVTEEDVEAFLEGVVLD
                     DGYKTMPSQLNILKSDDESEIELTIHEGKFHQVKRMFESVGKKVVYLKRLSMGNLKLD
                     ESLELGEYRELTDEEVKLIEER"
     gene            complement(2339..2668)
                     /locus_tag="PC494_001531"
     CDS             complement(2339..2668)
                     /locus_tag="PC494_001531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1904 domain-containing protein"
                     /protein_id="HDF3912035.1"
                     /translation="MPQIKIRGINENDICKISEKMINDLVEAVKCPRDYFEIECIKSV
                     AIRDGKIADVYPFVEVAWFDRGQEVQDIVARIITDSIRNNLDVESIDLAFTVFEKEKY
                     YENGEHF"
     gene            2998..3924
                     /gene="fba"
                     /locus_tag="PC494_001532"
     CDS             2998..3924
                     /gene="fba"
                     /locus_tag="PC494_001532"
                     /EC_number="4.1.2.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II fructose-1,6-bisphosphate aldolase"
                     /protein_id="HDF3912036.1"
                     /translation="MALITTKEMFKKAYEGGFAIGAFNISDLEQLQGVLKAAKAKNSY
                     VMIQASMSAVKYAGPHTLVEMVKAASDEIGVDVALHLDHGPNMDAIKTCIDAGFSSVM
                     IDGSHFDFEENVRITKEAVEYAHSKGVVVEAELGVLAGTEDDVTSDVHKYTQPAEAVE
                     FVERTGVDSLAIAIGTSHGAFKFKGEAKLRFDILEEIQSKLPGFPIVLHGASAVDQNA
                     VATCNEFGGNIAGAKGVPVDMLRKASSMAVCKINMDTDLRLAMTAAIRKFLAENPKEF
                     DPRKYIGAGRDAIQAVVESKIDDVLGSANSIN"
     gene            complement(4059..5690)
                     /locus_tag="PC494_001533"
     CDS             complement(4059..5690)
                     /locus_tag="PC494_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDF3912037.1"
                     /translation="MDNNLIGLIEHVENPAILCKESGEIIYCNHLIDSIFSFLDIKKP
                     RNINELDSNFDKTEILTDSKKKIAFRELRMTAHIYNMKDNNNENNIVYLFEKSLISDK
                     VIEDIIEHIDEVVVVFNKDGVIEKMNTVSDEILPFKRTEVLGRNITDLVRQGLVEEPI
                     ILNMLKVKKKIYRNIVYPDGKLIAYTAVPRWDSKGKLTGGVLTGRDISRVIKLESQIK
                     YSDISEDTEYISQSKIMDNIKKVVKRAAASDSSIFINGESGVGKEIIARTIYKYSSRR
                     DKPFIAINCGAIPNELLESEFFGYEEGSFTGAKKKGKKGLFEEANGGTIFLDEIGELP
                     MQMQKKLLRVIQENTITRIGGSKPIKIDVRYISATNISHEDLRNNLKFRQDLYYRLSV
                     IPVKIPPLRERKEDIVPLVNYFLKLYNEKYNREVEVSPKVIELLEEYSWPGNIRELKN
                     IIERFVVLSAKNVIGEDEFNMLINLDMIDNETDDLSPIVVNGIMNLNDAYKIVDQIMI
                     SKAINKYGSITKAAEVIGIYPSTIHRKIKSGHIHV"
     gene            complement(6173..7210)
                     /locus_tag="PC494_001534"
     CDS             complement(6173..7210)
                     /locus_tag="PC494_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit
                     alpha/FixB family protein"
                     /protein_id="HDF3912038.1"
                     /translation="MNDIKDLSSYKNVWIFAEQREGKIAPVVIELLGEGRKLAKEVDA
                     ELCAILLGKDVDGLAKELITFGADKVYVADDALLEKYTTDAYTKVIKDAIDEIKPEIM
                     LFGATHIGRDLAPRIASRVGTGLTADCTKLEIDPEDKKIKQTRPAFGGNIMATIICPN
                     HRPQMSTVRPGVMDKAEKDETRTGEVIALDYKITQDDIRTTVLETVKTKKDLVSLTDA
                     NVIVSGGLGLGGPEGFEMLKKLADKLGGVVGSSRAAVDAGWIDHSHQVGQTGTTVKPN
                     LYIACGISGAIQHLAGMQSSDFIIAINKNPAAPILEIADYGVVGDLHEIVPMLIEKLD
                     SVDDLLEAIKA"
     gene            complement(7229..8014)
                     /locus_tag="PC494_001535"
     CDS             complement(7229..8014)
                     /locus_tag="PC494_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012703997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit beta/FixA
                     family protein"
                     /protein_id="HDF3912039.1"
                     /translation="MKILVCVKQVPDTNEVRINKETGTLIRDGVPSILNPDDANALEE
                     ALKIKDEHDDVTITVITMGPPQADFMLRECLAMGADDAILLSDRAFGGADTWATSNTI
                     AAGISKVGDYDIIFAGRQAIDGDTAQVGPQIAEKLDIPQVTYVQDFKIEGKDIIVQRQ
                     LEDGYELIKVSTPVLLTAVKELNTPRYMSVDKIVKAYKHDVKVWTIDDLDVNKEEVGL
                     KASPTKVFRSFTPEPRGKGEILEGKADEIASKIIIGLKQKHII"
     gene            complement(8047..9180)
                     /locus_tag="PC494_001536"
     CDS             complement(8047..9180)
                     /locus_tag="PC494_001536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003483287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA dehydrogenase family protein"
                     /protein_id="HDF3912040.1"
                     /translation="MLYNKEQELLRKAVRDFVSKELDTLPAEMDKTGVMPKELIKKLA
                     DAKFISSNIPEEYGGGGAGYVSYAIVMEEIARRCASTATFVTAGSSLASLPILYNGTE
                     EQKQKYLKGIATGELIGAFGLTEPGAGSDAGGQQTTAELVGDHYILNGRKTFITNGPF
                     CDVAIVIAVTDRSKGLRGTSAFIVESKWDGFSTGAHEDKMGIRGTETSDLIFENVKVP
                     KENLLGKEGQGFKIAMGTLEVGRIGVAALALGIAQGALDEAVKYTKQRVQFGKPIAKF
                     QNTQFTIADMETKVCAARGLVYDAAQKRDAGMRVAQESAMAKYYASEIANEVAYKALQ
                     LHGGYGFIKDYEIERMYRDARIVSIYEGTSEVQKMVISSNVLK"
     gene            complement(9228..10355)
                     /gene="hadC"
                     /locus_tag="PC494_001537"
     CDS             complement(9228..10355)
                     /gene="hadC"
                     /locus_tag="PC494_001537"
                     /EC_number="4.2.1.157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(R)-2-hydroxyisocaproyl-CoA dehydratase subunit
                     beta"
                     /protein_id="HDF3912041.1"
                     /translation="MEAILSKMKEVVENPNAAVKKYKSETGKKAIGCFPVYCPEEIIH
                     AAGMLPVGIWGGQTELDLAKQYFPAFACSIMQSCLEYGLKGAYDELSGVIIPGMCDTL
                     ICLGQNWKSAVPHIKYISLVHPQNRKLEAGVKYLISEYKGVKRELEEICGYEIEEAKI
                     HESIEVYNEHRKTMRDFVEVAYKHSNTIKPSIRSLVIKSGFFMRKEEHTELVKDLIAK
                     LNAMPEEVCSGKKVLLTGILADSKDILDILEDNNISVVADDLAQETRQFRTDVPAGDD
                     ALERLARQWSNIEGCSLAYDPKKKRGSLIVDEVKKKDIDGVIFCMMKFCDPEEYDYPL
                     VRKDIEDSGIPTLYVEIDQQTQNNEQARTRIQTFAEMMSLA"
     gene            complement(10355..11581)
                     /gene="hadB"
                     /locus_tag="PC494_001538"
     CDS             complement(10355..11581)
                     /gene="hadB"
                     /locus_tag="PC494_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(R)-2-hydroxyisocaproyl-CoA dehydratase subunit
                     HadB"
                     /protein_id="HDF3912042.1"
                     /translation="MSEKKEARVVINDLLAEQYANAFKAKEEGRPVGWSTSVFPQELA
                     EVFDLNVLYPENQAAGVAAKKGSLELCEIAESKGYSIDLCAYARTNFGLLENGGCEAL
                     DMPAPDFLLCCNNICNQVIKWYENISRELDIPLIMIDTTFNNEDEVTQSRIDYIKAQF
                     EEAIKQLEIISGKKFDPKKFEEVMKISAENGRLWKYSMSLPADSSPSPMNGFDLFTYM
                     AVIVCARGKKETTEAFKLLIEELEDNMKTGKSSFRGEEKYRIMMEGIPCWPYIGYKMK
                     TLAKFGVNMTGSVYPHAWALQYEVNDLDGMAVAYSTMFNNVNLDRMTKYRVDSLVEGK
                     CDGAFYHMNRSCKLMSLIQYEMQRRAAEETGLPYAGFDGDQADPRAFTNAQFETRIQG
                     LVEVMEERKKLNRGEI"
     gene            complement(11596..12396)
                     /gene="hadI"
                     /locus_tag="PC494_001539"
     CDS             complement(11596..12396)
                     /gene="hadI"
                     /locus_tag="PC494_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxyisocaproyl-CoA dehydratase activator
                     HadI"
                     /protein_id="HDF3912043.1"
                     /translation="MYTMGLDIGSTASKGVILKNGEDIVASETISSGTGTTGPSRVLE
                     KLYGKTGLAREDIKKVVVTGYGRMNYSDADKQISELSCHARGVNFIIPETRTIIDIGG
                     QDAKVLKLDNNGRLLNFLMNDKCAAGTGRFLDVMAKIIEVDVSELGSISMNSQNEVSI
                     SSTCTVFAESEVISHLSENAKIEDIVAGIHTSVAKRVSSLVKRIGVQRNVVMVGGVAR
                     NSGIVRAMAREINTEIIVPDIPQLTGALGAALYAFDEAKESQKEVKNI"
     gene            complement(12435..13634)
                     /gene="hadA"
                     /locus_tag="PC494_001540"
     CDS             complement(12435..13634)
                     /gene="hadA"
                     /locus_tag="PC494_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isocaprenoyl-CoA:2-hydroxyisocaproate
                     CoA-transferase HadA"
                     /protein_id="HDF3912044.1"
                     /translation="MLLEGVKVVELSSFIAAPCCAKMLGDWGAEVIKIEPIEGDGIRV
                     MGGTFKSPASDDENPMFELENGNKKGVSINVKSKEGVEILHKLLSEADIFVTNVRVQA
                     LEKMGIAYDQIKDKYPGLIFSQILGYGEKGPLKDKPGFDYTAYFARGGVSQSVMEKGT
                     SPANTAAGFGDHYAGLALAAGSLAALHKKAQTGKGERVTVSLFHTAIYGMGTMITTAQ
                     YGNEMPLSRENPNSPLMTTYKCKDGRWIQLALIQYNKWLGKFCKVINREYILEDDRYN
                     NIDSMVNHVEDLVKIVGEAMLEKTLDEWSALLEEADLPFEKIQSCEDLLDDEQAWAND
                     FLFKKTYDSGNTGVLVNTPVMFRNEGIKEYTPAPKVGQHTVEVLKSLGYDEEKINNFK
                     DSKVVRY"
     gene            14311..15309
                     /locus_tag="PC494_001541"
     CDS             14311..15309
                     /locus_tag="PC494_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-2-hydroxyacid dehydrogenase"
                     /protein_id="HDF3912045.1"
                     /translation="MKILVFGARDYEEPVIKKWSEEHKDVQVDIYPENMTEENVVKAK
                     GYDGISIQQTNYIDNPYIYETLKDAGVKVIASRTAGVDMIHFDLVNENGLIVTNVPSY
                     SPNAIAELAVTQAMNLLRKTPLVKKKVCEGDYRWIAELLGTEVRSITVGVIGTGKIGA
                     TSAKLFKGLGANVIAFDQYPNSDLNDILTYKDSLEDLLKEADLITLHTPLLEGTKHMI
                     NKDTLAIMKDGAYIVNTGRGGLINTGDLIEALESGKIRAAALDTFETEGLFLNKKMNP
                     GELTDPEINKLLSMEQVIFTHHLGFFTSTAIENIVYSSLSSAVEVIKTGTATNRVN"
     gene            15671..16198
                     /locus_tag="PC494_001542"
     CDS             15671..16198
                     /locus_tag="PC494_001542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR04002 family protein"
                     /protein_id="HDF3912046.1"
                     /translation="MEKMNKVTSKKTTYIVTSALFASIICLTIAYILHIPVGGNNGYV
                     HIGDAFIYLAATILPTNYAIAASAIGAGLADLSTGAAIWVIPTIIIKPILVLFFTSKS
                     DKIINKRNIVASVVAGIVGLVLYMFAEGIIIGSFTSAFVMSLLGLLQPIGSFIVFIIL
                     GMALDKLDFKKRYFN"
     gene            16225..16821
                     /locus_tag="PC494_001543"
     CDS             16225..16821
                     /locus_tag="PC494_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR04100 family radical SAM protein"
                     /protein_id="HDF3912047.1"
                     /translation="MNILYTIENSIYVNITNTCPCSCVFCIRNEKDEVANSGSLWLEH
                     EPSVDEVKEAFNKYNLDDYDEIVFCGYGEPLMRINELIEIAKFIKEKSSIKIRINTNG
                     LSDLIHNKKTAILLKNVIDAVSISLNAPNKEAYNRVTQPKFGEKSFDYMLDFARDCKK
                     YIKEVAFSVVDEISPEEIEESKQLAKKLDIPLRVRHKN"
     gene            complement(16886..18469)
                     /gene="asnB"
                     /locus_tag="PC494_001544"
     CDS             complement(16886..18469)
                     /gene="asnB"
                     /locus_tag="PC494_001544"
                     /EC_number="6.3.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase (glutamine-hydrolyzing)"
                     /protein_id="HDF3912048.1"
                     /translation="MINLEEKYLTRKDTYMIKILEYNGHIRNWKVLCEELGIDSSLCR
                     DERERAILVEAYKTWGYDMANHMHGMFAFALWDTVEKKLFCLRDQFGVKPFYYYETEN
                     GKLLYGSSIRKIMEQPGFVKELNEDMLQIYMSFTYVAGENTFFRGVKKLMPGHYLVYQ
                     NKTVCIGRYWKPEFHPDHSKSIEEWTDEIHTTLQKIMPEVKSENETAELFLSGGVDSS
                     YILAMSDIEKTGSCGYEEERFDESKLAQQTANILGCKNSRYIITPEEYFASVPYVMYH
                     MEQPTGDASAIVFAIGCKAAAENTNICYSGEGADEFFGGYNIYHKAECYGENLKTFYI
                     GNTNIMNEGEKRKILKKYNPDVLPIEVVKGIYEETEELDTLTNMSNVDIQIWLEGDIY
                     FNIDKMSTAVGLEVRMPLTDTRIFDIASRIPSEYKVKGKENKIAFRTAASKTLPEEIA
                     FRNKLGFIVPIRIWMADDRYNKDIRDKFNSEIADKFFNIDEINEIFNDYISGNSDNWR
                     KIWMIYTFLVWYEIYFVKC"
     gene            complement(18534..18671)
                     /locus_tag="PC494_001545"
     CDS             complement(18534..18671)
                     /locus_tag="PC494_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3912049.1"
                     /translation="MKNKKFNVITLIILDNHIYAINKEQISTNSKRIYFEKSRFFSDY
                     K"
     gene            complement(19035..19871)
                     /locus_tag="PC494_001546"
     CDS             complement(19035..19871)
                     /locus_tag="PC494_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HDF3912050.1"
                     /translation="MNYIIKKVLNSSVVLVHDAKYNEFILLGKGIGYGKKTGEYICGS
                     NDNQMFVPVENTKSKQFLELMDDIPVDILKITQEIIVEAEKLLNSSFNKNLYLILADH
                     FNFAIERMRKGIKITNRVFWEIKNYYPNEFKVGMVAIYMVEERLGIQLPEEEAANIAF
                     HFANAMASDGNSYDTIKYAKVIGEIINIFVFSLNRTLDKKSMHYMRFITHIKFFVERF
                     FSDSMLSSGDDLLFNQMKRSNPKEMLIALKVRDFLEKKYGKKLTNEEIAFLVVHIARV
                     KQ"
     gene            complement(19895..21361)
                     /locus_tag="PC494_001547"
     CDS             complement(19895..21361)
                     /locus_tag="PC494_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000110363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HDF3912051.1"
                     /translation="MRKFPEGFLWGGATAANQFEGGWNLGGKGWSVSDVAKAHFDADV
                     KDYKSNNEITTKDIEEGLAHPEDEVNYPKRHGSDFYHHYKEDIALMAEMGFKTYRMSI
                     AWSRIFPNGDDKEPNEEGLQFYDDVFDELISYGIEPLVTMSHYEPPLNIVLNYDGWYS
                     RQVINMFVRYVETICERYKNKVKYWLTFNEVDSMIRHPYTTGGLVRDRFKDKNFEEVI
                     FQAMHHQFVASAIATKICHEIIPNSKVGCMLTKLTYYPYTCRPEDVLATQQKMRSIYA
                     YSDTQVFGEYPVYLLSYFKNNNIQIVKEEHDDEIMKKYPVDFISFSYYMSSCEAADTT
                     GLDITPGNTLLAVKNPYLEMSEWGWQIDSIGLRISLIELYDRYRKPLFIVENGLGAKD
                     ILTEDKKVHDQYRINYLKEHFKCMLDAIIEDGVELWGYTSWGCIDLVSESTKQMSKRY
                     GYIYVDADDYGKGTYNRYKKDSFYWYKKVIENNSIDFK"
     gene            complement(21364..23226)
                     /locus_tag="PC494_001548"
     CDS             complement(21364..23226)
                     /locus_tag="PC494_001548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HDF3912052.1"
                     /translation="MNYKKTAIDIIEQVGGSKNILALEHCSTRLRFKLIDRSKVNQDA
                     LKKVQGVMSIVNGAQFQVVIGNSVVDVYDEILKVCPLDTNDSTVKTEEKINLGTRFIE
                     FIINIFQPLIFAIAGAGILKSLLMLLAMFNILKSDSTIYTLLVAISDATFYFLPLMVA
                     VTTANVLKCNRLVAIAAVGYLLLPATTTALSEGVELFGFTIPNIAYNAQVFPAILCVS
                     FLATMEKIFNKYSPKPIRTFFVPMMSLAITVPITLTILGPLGYNVGTIFTTIILFLYN
                     KMGFLVVGLLAAFLPFMVATGMHKALIPYSINTIGKLGYEALYMTSSLAHNISESGAC
                     FAVALRTKDETLKQTALSAGISALMGITEPALYGITLQHKRAMLGVVFSSAISGTFLG
                     LFAVKGFVIVGPGLASMSMFIDPNNGNNLIFASIGFVIAILGSFIITLIIWKEDTNTV
                     ESSIGDVVEEELEEEKEVNILVTPVEGKVIDLSKVNDELFASKTLGDGVAIIPTNGNL
                     YAPCDSEVVMLFETKHAIGLRTKNGAEILIHIGINTVSMNGDGFKTFVKTGDNVKEGD
                     LLIQFDLDKISHANLDSTVMIVNNNGADYAYKVLNQSYGNVKKGSILFDVKGGI"
     gene            complement(23473..24336)
                     /locus_tag="PC494_001549"
     CDS             complement(23473..24336)
                     /locus_tag="PC494_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HDF3912053.1"
                     /translation="MILSYFALLIRVVLLAFERVVVRLLGDEEGDIYKNIASSFLFFF
                     IGGVCLLPFSIMDRVSDWSFLIPCYISSLVYSIGSVAYVTSLATGEVSLVTPINSLNS
                     LFLLLLSVIFLGEGLSLAKVAGIIIMIGGVFILKKVSSFLKNVSVIFNNLPCRLMFLY
                     IFLQSVGRVLDKAFFVQVSPILYSTILYFFVGLNLFIFLAFKKKQKIICEIFTNKKGL
                     SILSGAINGYSYLALLIALNNLELSIAEPFSQVSMIITLILAHFIFKENIKEKIPGSI
                     LILIGGWLLLL"
     gene            complement(24391..25323)
                     /locus_tag="PC494_001550"
     CDS             complement(24391..25323)
                     /locus_tag="PC494_001550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-aminoacyl-tRNA deacylase"
                     /protein_id="HDF3912054.1"
                     /translation="MNNKKAVFFFCSDLKKDPVASNVIKCCEEIMDLNQTDIVIDDNF
                     VLEFKDKNNNLFHFVKTKDVISHNYKYYLPILNRHFRDYDFAGVVNWHEGENAPEHIL
                     TAHTIGDVPTGEFGNSNPRYFKNLINAIEDIKNENLLDEFTTLTEATHWSGTTYGEES
                     KLITEYSVPMLDIEIGSSSDSFNNSIAIQVLAKSLIRVFDCDEPLKTLLCVGGVHFEK
                     SFSDIIKNKEYNISIGHVLPNQWIVSGMYDDESGFEKLEKCINSIEGGIDCIVFHDKL
                     KGTYKEQCRKLGEKLNVPVFKHKILKNPKDLPIW"
     gene            complement(25409..25960)
                     /locus_tag="PC494_001551"
     CDS             complement(25409..25960)
                     /locus_tag="PC494_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF3912055.1"
                     /translation="MQSLNEIIAENLKKIRKEKHLSLDKIAQLSGVSKSMLSQIEKCE
                     VNPTISTLKKITNGLKISFTSLMERQESDIELIQKSDIDHFIEDNGKYISYPIFPFDS
                     KRRFEIFMIEIEEGGNLDSNAELPGTQEFITVFSGEVTIKINGEDYIVSSGNSIRFKA
                     DVSHIYRNSGKGIAKMSMVVYYI"
     gene            complement(26189..26680)
                     /locus_tag="PC494_001552"
     CDS             complement(26189..26680)
                     /locus_tag="PC494_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3912056.1"
                     /translation="MIDLKIENRKGKIHVKSSEIKDILELRPDFEYVQDISNTINQEN
                     ILVFDCQLTGNSFDMDDLDIEEILEELGEEIDESYFSVLFEDVRAYLKDATDEIEADL
                     QDNYLFDNLRCYFDIYNINQEFTDFKFVFLVSFKDIKISSLANLAKIVSKRQLIGASK
                     FYS"
     gene            complement(26708..27268)
                     /locus_tag="PC494_001553"
     CDS             complement(26708..27268)
                     /locus_tag="PC494_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HDF3912057.1"
                     /translation="MNKLNICIDIDGTITSPYHFLPYLNDIFNKNITEAECITHNWEE
                     LYGSGIRDVYAEFNNKYIHSYDEAKIVEGATEVISTLSKGHNLSFVTARHECLTDVTK
                     NWLSRQGFSDIDVYLLGSDYKVEKARELSCDIFIEDNPLNSVQLADDGVKVILLDTNY
                     NKDVKHQNIVRVSNWIDIEKIIKQGI"
     gene            complement(27420..28577)
                     /locus_tag="PC494_001554"
     CDS             complement(27420..28577)
                     /locus_tag="PC494_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase"
                     /protein_id="HDF3912058.1"
                     /translation="MNKQSIGKLNMFFMGITQRNLDNRDFFIELEVIFKSGRKEFKGI
                     AIEEDNKYKFNFKGKSDLYTFNELLKNISKEAENYDGLVFKYVERGTIVVIEGDNKKV
                     NVKYLDNKEEVPKIDEFTASQIKNRDYYVKVGQANALLKEIGVLTKDGKIKNDKIRKY
                     NQIDHFVELIDSILKEIKDKDCITILDCACGKSYLSFVLNFYIKEVLKKNCYFIGIDY
                     SDVVIEASKNMAKNLGYKNMSFIKEDLTNYTPNRDVDLVISLHACDTATDMAIGLGIR
                     AKSEAIVVVPCCHKELLGQYRYEAMEPILKHGVFKARFADLITDGLRTLLLEGNGYDT
                     SVVEYISPLDTPKNLMIRAIKTKTNNDKALKEYKELKSQFGVEPTLEKLIY"
     gene            complement(28614..29555)
                     /locus_tag="PC494_001555"
     CDS             complement(28614..29555)
                     /locus_tag="PC494_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3912059.1"
                     /translation="MRWILVFIFLYLIPLVVIFRNYKNFKRSCIYSSIYVVLATTIMI
                     SNIYMSGLNKIKESMYYHNYISDETYDEKYVSNFKEKESTDLKQDNKKNEEISNNKNL
                     NNKQDRNIQNKESNEEGSNDIKEKNNSDSNVSVNNKSEKQEDNTKENNKYTSKEKNSE
                     DIKKIDMESIGIFKKEIYNIERAALVPMRECIPYTKDIAKNITKLSSIKKDVTNARNK
                     CKEVVKEYENMQIPELSKEKYTETLSNARDDVKKAYELREKSMESALKLINTKSPKYI
                     GKITEYLDLSDKQIESFKNRLNDLKEEINNSETNNIN"
     gene            complement(29642..30334)
                     /locus_tag="PC494_001556"
     CDS             complement(29642..30334)
                     /locus_tag="PC494_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HDF3912060.1"
                     /translation="MSLYAIGDLHFSTSVNKPMNIFGSNWDGHEKKIIDNWKEVVKEE
                     DMVLVLGDTSWGINLSEAKKDLDIISKLPGQKILIKGNHDYWWTTVTSLNKLYEDMRF
                     IQTNFYEYKDYAICGGRGWICPNDVKFDETDEKVYKREEHRLRLSLESARKSGHSKII
                     VITHYPPTNDKLEESLFTKLFEEYNVEKVIYGHLHGKESFKMGLKGIRNGVEYTLASC
                     DYTEFNLIKVHD"
     gene            complement(30443..31255)
                     /locus_tag="PC494_001557"
     CDS             complement(30443..31255)
                     /locus_tag="PC494_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HDF3912061.1"
                     /translation="MEYEKWNEILAPYEHAVEELKIKFKNIRKEYLAKGEYSPIEFVT
                     GRTKKISSIISKLKRINAKDIETEIDDIAGIRIMCQFVEDIYAIVDLIKVRNDMTIIG
                     EKDYITNYKDSGYRSYHVIIKYPINSIAGSKEIICEIQIRTLAMNFWATIEHSLKYKY
                     DHYIPETLAERLRRASDAAFLLDQEMSEIREDIMKAQAMYQMKSIAIRDTLNRIQELY
                     DLGDTHKAMQYQRKLDRTETDKNITEILELKQEIDILLEQYKDTKVDDKVVQ"
     gene            complement(31306..32217)
                     /locus_tag="PC494_001558"
     CDS             complement(31306..32217)
                     /locus_tag="PC494_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HDF3912062.1"
                     /translation="MNLTKVKGNTFFIKGGTNTGIYVFEDNTALMIDPGLCGSRPRRV
                     NKVLDENNIQVRYIINTHGHDDHYGACNQFKEYYKDVCIMSSEYDKLYIENPELFSKY
                     IVGGKSNVFMDNILKNKMLDDIKIDKSIEAGKIELNNEMFDIIEFQGHTPGSIAVLTK
                     DNVIFVGDLLIGDEILSKYDFLFLYDIQEQINSLEKLKNIDFEYLVLGHGKQVISKED
                     SYKLIEKHLNALKKYLYQIRELLVEPKSLEILLKNIINNNNLSNNYKEYHFFKSSLVS
                     VISYLVDLEEIGYILENGELLYYTKTK"
     gene            complement(32276..33007)
                     /locus_tag="PC494_001559"
     CDS             complement(32276..33007)
                     /locus_tag="PC494_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkgJ family cysteine cluster protein"
                     /protein_id="HDF3912063.1"
                     /translation="MTSIKNKDILNCIDYSIKNKLFDKLNDVYKSLPVGNCSGCGNCC
                     MESVGINLIEFLNIFCYLEDRVDLKKSCISKILDYYFEEYTRKNPCPFKDTNNRCLIY
                     EVRPLNCRMFGHWKKEDYNKNLDNVIEKNNNYRELMKKQYGFEINDEVVNYRIDYCDR
                     FIPNKDYLSKSKRLSFFDELMILDSNIYSSGNIDIDFRDRGIVEYFIESLLYRNLAYN
                     VKIRISKEYKIRKRTIDRIKRIVLV"
     gene            33096..33347
                     /locus_tag="PC494_001560"
     CDS             33096..33347
                     /locus_tag="PC494_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3912064.1"
                     /translation="MNRYTKIINMMGSYYTKDFEKEKKNVIKVREVKEDTVRKFFLQG
                     DCEVLVVFEDTGKEILIDDFSPEEDIKKYLGAKFINKKR"
     gene            33581..34000
                     /locus_tag="PC494_001561"
     CDS             33581..34000
                     /locus_tag="PC494_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3912065.1"
                     /translation="MQIYFRVKAVGKRKPMLELTPFDISDNINCLKEAISEIVSKNVL
                     EYNEKIPEKSIINFLTNEEIESQADIGKVGFGSIYNENKQSVEKAIEVALQAFEDGIY
                     KVLINEDVIEKLDSSINLKSGDIFTFIRLTLLAGRMF"
     gene            34025..39082
                     /locus_tag="PC494_001562"
     CDS             34025..39082
                     /locus_tag="PC494_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4132 domain-containing protein"
                     /protein_id="HDF3912066.1"
                     /translation="MLERTRVEKNPKIIENFKNNFTKSSSKQYYDLAKSLWDCIENSS
                     YYYREPEDKFLNMIKKYYNCHYYEIKNMDELLSGPLKNALELIFTSEQVEELCQLIKR
                     KMDYTYSGGYYRKGYRSNKLVDYFRGIIRFISNYVDLIYYDFSVIDYLTLPNKVLYYD
                     SIMSDKIALEIDKGNQKVISALEEVIFGENQTALLTRQMIIGIMKSHSDKCYEMLSKL
                     LLAAKQQEGLRQQIVESLDEGTISASIYMLKTILDNNLERFSSVIRALDTWTGLGFSD
                     QKPGIIRKCLELSYKSLTDEKFRIESINSNDNLEIYFALWATATYNIYDSYSLIENLL
                     SCQEKYKKLVALYFLSHTESTYFKHSIASKNIKGDDLEILAWVITNFYVEGSVGYYYS
                     WQNRETNFDLSNTPIDKDFDARKEQFESLKHTLEILNSKTKSFSGSVFPWTWIEISSH
                     EILKCMMTLTAYDMNAQFIDVLMENCHLMSSDLRASLIVNFVNEPKTDRQREFLLECL
                     SDKSVSNRETVLSLLRKLELTDVELDKITNLLSLKTSSIRQTVIKILLEQDDSNLENI
                     ASSLIKSSNSQKCLGGLEIVNLLKDNTARQELYNKLILLIEDIDKSKKNTSQVQILID
                     NLLGKAKNDYCKENGFGIYNPENKVQIPEQFDFKDDSNSSSKLNKIISNISLSTREDS
                     VSVATKKEAKKILDTDINKIIKVYEKFDELITENADYEYEVERWSGNVDKVLLGYSTY
                     NLTPIKYKVSNDTLDNYPLAELWRETSKKLDLDYKLILDILFYSISTCGYNETEKSWF
                     SSIYSNVLDSKKQNKIYTKLEKLKFNGLTRKLLRVLLNEFDHKEIFNYCLEIYYKLRN
                     LLTIEQCKKQRVEFTKNYYRQNEYCPALNAPILNYWLDKAHSFIYDDISFTKFFYTTF
                     SNYQLLEYKFPFYTSINVFARAHELGLMTEEQVNREMISGYNASNIIRTLTNPRWAGD
                     TLEKYPWLKDNLKTVTNRIIEIESRRGDMPTEVSNLANNIQYFEGINYFVNILVALGK
                     ETFQRGYSYGSNYSKKDVLSSLLKNCYPTKEDDSKKLKSLLKNTDITELRLIESAMYA
                     PQWVNIIEKYLNWKGLKSTIWYFHAHINEGFSAQKESEVALFSPISPRSFIDGAFDVD
                     WFLDSYKTIGEERFNILYKSAKYITSGGNSHRRAQLYADATLGKLDKDMLMKEIETNR
                     NQDKLRSFSLLPMKKGDLKEATFRYEFIQKFAKESKQFGAQRRESESKACTIALENLA
                     RSAGFGDVNRMMWALETEKLNEVAHLFKPKDIDGTSIWIDVDENGKASTKVQKGNKSL
                     KSIPKAIAKHPYVLELKSVQKDLKSQYSRAKQSLEQAMKNEIVFTVKEIANIYKNPVI
                     CPLIKNLVWVCDDNIGYVYNDKSKFFICNIEGETYKLTAKNKLKLAHPVHLFESGKWS
                     EFQHDLFSKQIVQPFKQVFREYYRINSDELSEKTISRRYAGHQIQPKKTVALLRNQLW
                     TVDYEEGLQKVFYKENIVAKMFALADWFSPADIEPPTIETVEFFDRKTYKSLELASIP
                     PILFSEVMRDIDLVVSVAHAGGVDPETSHSTVEMRIAIAKELLLLLKINNVNFEGSHA
                     LIAGNLGEYSVHMGSGIVHKKGMGALNILPIHSQSRGKIFLPFADEDPKTAEIMSKIL
                     LLAEDSKIKDPSILSNL"
     gene            complement(39267..40004)
                     /locus_tag="PC494_001563"
     CDS             complement(39267..40004)
                     /locus_tag="PC494_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF3912067.1"
                     /translation="MIKVLICDDDKIVRDDIANIAKESGYVDYVKKVKDGIEAIEFIK
                     NEKIDLLIIDIDMPYKNGIDSAEEILSIDKDIHIVFVTGFADYSLESFKVHPIDFVVK
                     PFKKEKILDSINIAIDHINSHKIANNNFIEDTLFVYKIRKQIHMINFDDIVMFEKNSR
                     AINLHTKDEDIIKFYENFDDLKKRLPPNFFMTHRQYIVNLRFIHKVIPINKSSLEIRF
                     INFQENAILNKSLEKDFLYRFYRVKRF"
     gene            complement(40023..40958)
                     /locus_tag="PC494_001564"
     CDS             complement(40023..40958)
                     /locus_tag="PC494_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HDF3912068.1"
                     /translation="MDNNFVFPIVILTLFIFSNLIMNKYKFYKELDILKRGILTFFIS
                     CFALILFMEGTKYIQLRLGYSFLLEGVLNIILFLVLIILSFYTGFKVIRLINNNNEQE
                     YKLQKLDSKINHKDNIIIKLRSQKHDYLKHLQVVYSLLNTGLDEDAKEYIMNISNSFK
                     SKNSRYGKVSYLDAIASLKYEECLEKDISFDVYIQDFMDNLEIEPNDMSSVLLNIIDN
                     AIESLSTIKKEKKYIRLHAYEDEFQYIIAIKNNGPKIHNVESIFWNGFSTKEGQDRGY
                     GLHLVKNILDKYDYSILVNSDDFLTEFVILIPKYY"
     gene            41166..43742
                     /locus_tag="PC494_001565"
     CDS             41166..43742
                     /locus_tag="PC494_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HDF3912069.1"
                     /translation="MKDNLKIVLRYIKSYKARSLAIVVSIILATSLVVGIGTLSRSAQ
                     QADVDRLKRELGTDHVYFKNIKKNQLKSIKSSKDIKNLGITSYYASTDVNEKLPINIL
                     YTNKNYLTSHSKLIKGRFPKASNEVVVEKWILNSMGLKPEINQNLTFKLYQKENPETF
                     KVVGILEDRFIEKKKGQCEIFSNLNESELNDFTTYIEFNEGSDINTNIDNIIKNAMLD
                     EKSIGRNSMLIESTMKNGTLDNSSKYVAIAMSLFAGIVIYSIYVISIYQRVQEYGVLR
                     AIGSTNFRIFKLMLYELFILALIAMPIGICIGMGGAQIFNRSVGNIQFEGNINVTPFV
                     IPDKIILLSIACTILIILIISFFTYLKIRRISPIDAIRKTFGADKNVTKVNYLISKLT
                     LNMSVTKSISAKNIFRNKKGFIIIVLSMSIGGIIVIKDNYKYSFLDVQNKSTQEQTYM
                     NADFILSNVYLNEIGNNTSFKDIKGFNDNQIDKIKNIDGIDKVKTASILNTRIEVNKI
                     NRLDYYEAINSTPYYKLNPLFIKNKTTGKYTLKQKLKGYNDEMIKSLEKYLVSGNINL
                     KKMKKENLAIVYVPEISKTQKYTKTFTPGEGTPAVDIKVGDTIKVKYPKGGMDTGLYE
                     SLKDNYEYLEYEFKVGAIISYPFADNGMYSGDDGVDVITSSEYLKKLTGVDKYNLVYA
                     DLNENANKKKINNLLGKIGSEVPGTTTVDMMVEKENSDKMTSRTMIYSYGIVAIMFII
                     SVLNIINNISYNLTSRTSEFGMLRAIGISERGFKNMILYEGILYGVLSSIITIVSGII
                     IQFKMYYMQGFVSYGLGFSIDYKIYILVVVANIIVGILATYIPSRKINKISIVEAINI
                     TE"
     gene            43754..44425
                     /locus_tag="PC494_001566"
     CDS             43754..44425
                     /locus_tag="PC494_001566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF3912070.1"
                     /translation="MPILETINLGKIYGKKETSVHALKNANLKINKGEFVAIIGPSGS
                     GKSTFLHLVGGLERPSNGTIKVDGKDICCLSDKELARYRRQKVGFVFQQYNLIPVLNV
                     KENIELPLKLDNKKIDKEYIDDLINLLGLNERKNHLPNQLSGGQQQRVAIARALSAKP
                     SIILADEPTGNLDSKTTEEVMDLLKSSIKKYNQTLIIITHNENIARKADRIISIIDGE
                     LKLTL"
     gene            44452..44793
                     /locus_tag="PC494_001567"
     CDS             44452..44793
                     /locus_tag="PC494_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3912071.1"
                     /translation="MLLILGNLNLNLDFDYRIIREENEDVDIFIDINYRSLDIDTDGS
                     NLFNSRIQFPFVRALILRLNKNNQCMTIHLLRDIDLFSAFANFEVDYTDSIINIKNQN
                     EKVILNKSIKK"
     gene            complement(45153..47795)
                     /gene="adhE"
                     /locus_tag="PC494_001568"
                     /gene_synonym="adhC"
     CDS             complement(45153..47795)
                     /gene="adhE"
                     /locus_tag="PC494_001568"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HDF3912072.1"
                     /translation="MEKKEKVVEKSNVEVCSPEIVNSVETLRMRLEEIRLAQKEFATF
                     TQEQVDKIFLAASTAANQQRIPLAKMAVEETGMGIVEDKVIKNHFASEYIYNAYKDTK
                     TCGVIEKDEAFGFTRIAEPVGVLSAVIPTTNPTSTAIFKSLIALKTRNGIIFSPHPRA
                     KNCTIEAARVVHDAAVKAGAPKGLIGWVDVPSIELTNVVMAEADLILATGGPGMVKSA
                     YSSGKPAVGVGPGNVPAIIDESADIKMAVSSILVSKSFDNGMICASEQAVIVPEKIYE
                     EVKKEFKYRGAHFLNKEETEKVGKVVIIDGSLNARIVGQPAHVIAKMADVEVPKTARI
                     IIGEVESVELNEPFAHEKLSPVLAMYKSKSFEDAVAKAEKLVADGGYGHTSSLYADSI
                     NHPERVEKFVNAMKTCRVLVNTPSSQGGIGDLYNFKLAPSLTLGCGSWGGNSVSENVG
                     VKHLLNIKTVAERRENMLWFRAPEKVYFKKGCLGVAAREFKDVMDKKKAFIVTDSFLY
                     NNGYTKKLTDLLDEMGIKHTTFFDVAPDPTLACAREGAKAMADFQPDLIIAVGGGSAM
                     DAGKIMWVMYEHPEVDFQDLAMRFMDIRKRVYVFPKMGEKAYFAAIPTSAGTGSEVTP
                     FAVITDQDSGVKYPLADYELMPNMAIIDADMMMEMPPRLTAASGVDALTHALEAYVSM
                     LRTEPADGLALQAGKIIFEYLPRAYKNGKNDKEAREKMAMASTMAGMSFANAFLGICH
                     SLAHKLGAFHHVQHGVANALLINEVIKFNCAEAPNKMGAFSQYRYPDCIQRYAEFASF
                     AGIKGSTDQEKVDNLIKAIDELKAKVGLPKTIKEAGVEESKFLERLDAMVEQAFDDQC
                     TGANPRYPLMSELKEIYLKVYYGK"
BASE COUNT        16134 a         8111 c         5798 g        18050 t
ORIGIN      
        1 atcattcttt agattaaata tattttcaca taaaaaatag atattaaatt tataaattta
       61 atatctattt ctataattaa aacttttttt atttcgtatt cccacactcc atatatataa
      121 ctacagacac atcaaaacac cttttcaatt ctttattcct aattttatta ccctctaatc
      181 taaatattat atgtctatga aactgtctaa agctcaagat ttctagcatt attttcgacg
      241 tagcaacact acagtctcac aatgtggcgt atttgggaac atatccatac acttaaccat
      301 cttaatctca taaccatacc ccttaaaatc aaccaaatca acaaccaaag acttaggatt
      361 acaagaaata taaacaatct ccttagcacc aaatccacaa atatccctaa tagcatcctt
      421 atgaatgcct ggtctaggag ggtcaacaat aatcaaatca ggcttgtcct ttaaatcctt
      481 aacaacctta gccacatccc cagcaataaa ctcacaatta gtaagtccat tcaacttagc
      541 attctcatta gcagcaacaa cagcttcctc aactatctca ataccataca ctttcttagc
      601 agcaccagcc ataacctgtc caatagaccc agtaccacta tacaagtcaa atacaacttt
      661 atcattgtaa tctccaataa aatccctagc aatactataa agaacctctg ctcccttagt
      721 attggtttgg aaaaacgaaa atggtgaaat cttaaactta agacctaaaa tttcttcttg
      781 tatataatct cttccataca atactcttaa ctcatcacat tggactgcat ctgctaaacc
      841 atcattaata gtatgaagta cacctactaa ctcagctttt aaatcaatcc ctaaaagcat
      901 atctttaaac tcatacatat caaaatcttc ttgagaagaa gttactatat taaccataat
      961 ctcattagta tgaatccctt ttctaactac aagatgtctc aaatatcctt tgtgattcat
     1021 tgttctataa taaggaagct ttttttcatt gaaaaactct acactagaaa ctaatatctt
     1081 tgagaagtct tcatcaacca acatacactc ctcaacagtt tgtatatcta tatgctttcc
     1141 ttttttatga agacctaatg tcaaaggtcc attttttact tcatctccaa aagtatattc
     1201 catcttattt ctataatatt tgttttctgg acttccttct atccctaaaa actgaaatcc
     1261 aaataaatct tgctttaaaa ataaatccat aacttgtttt tcttttattt ctaattgttt
     1321 ttcatatggc acagacaata gtgtacatcc tccacactct ctaaagtgct tgcaagtttc
     1381 ttcagtttca agtggtgagt tctctaataa ttctatcatc ttaacttcag ctttcttact
     1441 tctaactttt ttaactccag ctctcacctt ttgaccactt attccaccct tcatatggat
     1501 aactctatct ccaacttggc ttaaagatgt accaccaaat tccattttat ctacttcaaa
     1561 ttctataaca tcttttttct tcacagacat tcctccaatt tactatagta tctttattat
     1621 ctttcttcaa tcaattttac ttcttcatct gttaactctc tatactcacc taactctaaa
     1681 ctttcatcca attttaaatt gcccatagac aatcttttta agtatactac ttttttgcct
     1741 acgctttcaa acattctttt tacttggtga aacttacctt catgtattgt aagctctatt
     1801 tctgattcat catcactttt taatatattt aactgtgatg gcatagtttt atatccgtca
     1861 tcaagcacta caccttctaa aaaagcttct acatcttctt cagtaactac tccatcaatt
     1921 tttgcataat aagtcttagg cacatgcttc ttaggagata aaactctatg agaaagcttt
     1981 ccatcattag ttaaaactaa taatccctct gtgtctttat ctaaccttcc aacaggaaat
     2041 ggttcaaaag ctaagtatga taaatcaatt aaatctaata ctgttgggtc atatttatct
     2101 gtagttgctg atatatatcc atcaggttta ttcatcatca aatatatata ttctctatat
     2161 ataacttctt ctccattaaa taatatctca tcattttcag tgtctacttg agttcctgga
     2221 tttgaaactt cacttccatt tactactaca gacccttgtt tacaatactt ctttatttca
     2281 cttctacttc cataacctaa atttgaaaga attttatcta tacgttgctt tttagccatt
     2341 aaaaatgctc tccattctca taatattttt ctttttcaaa tactgtaaat gctaaatcta
     2401 tactttctac atctaaatta tttcttatac tatcagttat tattcttgct actatatctt
     2461 gtacttcttg tcctctatca aaccaagcta cttcaacaaa aggatataca tctgctattt
     2521 taccatctct tattgcaact gactttatac attctatttc aaagtagtct cttggacatt
     2581 ttacagcttc aactaaatca tttatcattt tttcacttat tttacatata tcattttcat
     2641 taattcctct tatttttatc tgtggcatag tttatctcct ttattttaaa tttttagtaa
     2701 attatcatcc acttaattcc tttcgataac gtttgaagtg gtaacttctt ggtcaaggca
     2761 actattgtta tcagtatctc caaactaata aggtagttcc tacccttata gttagcatta
     2821 tatagctagt tttcctaaat tgtttatatt ctttattatt ttatttaatc ctattgtctt
     2881 ctatttaaca ttatacttgt aatttatagt tattacaatt tactatatac tttttttgat
     2941 ttaacgttat aatataagtg atgggtaaat tttaaaagtt aataggagga gtttaaaatg
     3001 gcattaatta ctacaaaaga aatgtttaaa aaagcttacg aaggtggatt tgctataggt
     3061 gcatttaaca taagtgactt agaacaatta caaggtgttt taaaagctgc taaagctaaa
     3121 aattcttatg ttatgataca agcttctatg tcagctgtta aatatgctgg acctcataca
     3181 ttagttgaaa tggttaaggc tgcttctgat gaaataggtg tagatgtagc tcttcactta
     3241 gaccatggtc caaatatgga tgctattaaa acttgtattg atgctggttt ctcttcagtt
     3301 atgatagatg gttctcattt tgactttgaa gaaaatgtta gaataactaa agaagctgtt
     3361 gaatatgcac actctaaagg tgttgttgtt gaagcagaac ttggtgttct agctggaaca
     3421 gaagatgatg ttacttctga tgttcacaag tatactcaac cagctgaggc agttgagttc
     3481 gttgaaagaa caggtgttga ttcattagca atagctattg gaacttctca tggtgctttc
     3541 aaattcaaag gagaagctaa attaagattc gatatactag aagaaatcca aagcaaatta
     3601 ccaggtttcc caatagttct tcatggtgca tctgctgttg accaaaacgc tgttgctaca
     3661 tgtaatgaat ttggtggaaa tatagctggt gctaaaggtg tacctgtaga tatgttaaga
     3721 aaagcatctt ctatggctgt ttgtaaaata aacatggata ctgacttaag actagctatg
     3781 actgctgcta tcagaaaatt cttagctgaa aatccaaaag aatttgaccc aagaaaatac
     3841 attggtgctg gtagagatgc tatacaagct gtagttgaaa gcaagataga tgatgtttta
     3901 ggttctgcta actctataaa ctaatataac ttttaaatat ttataaaaga aaagagatga
     3961 cttaaagtaa ttaaatttat ttttaagcca tctcttttaa gttgtataaa ttatgtatct
     4021 tataatattt taattatatt gtctttttaa actgacagct aaacgtgaat atgtccactc
     4081 tttatctttc tatggatggt agaaggatat atacctataa cttcagcagc ctttgttatt
     4141 gaaccatact tatttatagc cttacttatc attatttggt ccactatttt atatgcatca
     4201 ttaagattca taattccatt taccactatt ggtgataaat catctgtttc attatcaatc
     4261 atatctaaat ttatcagcat gttaaattca tcttctccaa ttacattttt agctgataat
     4321 actacaaatc tttcaatgat gttttttaat tctcttatgt ttcctggcca agaatattct
     4381 tctaataact caataacttt aggcgaaact tctacttctc tattgtactt ttcattgtaa
     4441 agttttaaga aataatttac taatggtact atatcctctt ttctttctct aagaggaggt
     4501 atttttactg gaataacact taatctatag tacaaatctt gtctaaattt aaggttattt
     4561 ctaaggtctt catgagaaat attagtagca cttatatatc taacatctat ttttataggc
     4621 ttactaccac ctattctagt aatagtattt tcttgtataa ccctaagtaa ttttttttgc
     4681 atctgcattg gtaactcacc tatctcatcc aagaaaatag ttccaccatt cgcctcttca
     4741 aaaagtccct ttttaccttt tttcttagct ccagtaaaag aaccttcttc atatccaaaa
     4801 aactctgact ctaataattc atttggtata gctccacagt ttatagctat aaaaggtttg
     4861 tctctccttg aactatactt atatattgtt cttgctatta tttcttttcc tacacctgat
     4921 tctccattta taaatataga agaatctgag gctgcagctc tcttaacaac tttttttata
     4981 ttgtccataa tcttactttg acttatatac tctgtgtctt ctgatatatc actatatttt
     5041 atctgagatt caagcttaat aacccttgaa atatctctcc ctgttagtac tcctcctgta
     5101 agctttccct tagaatccca tcttggaact gccgtatatg caataagctt cccatctggg
     5161 taaacgatat ttctataaat ctttttcttc actttaagca tgtttaatat tattggttct
     5221 tcaactaatc cttgtctcac aaggtctgtt atatttctac caagtacctc agttctttta
     5281 aaaggtaata tctcatcact gacagtgttc atcttttcaa ttaccccatc tttgttaaac
     5341 acaacaacaa cttcatctat atgctctatt atatcttcaa ttactttatc agatattaga
     5401 gacttctcaa ataaataaac tatattattt tcattattat tatctttcat attgtatata
     5461 tgtgcagtca tccttaactc tctgaaagct attttctttt tactatctgt cagtatttct
     5521 gttttgtcaa aatttgaatc taattcattt atatttctag gcttttttat atctagaaaa
     5581 ctaaaaatac tatctattag atgattacag tatattattt cgcctgattc tttacataaa
     5641 atggctggat tttctacatg ttctataagc cctattaaat tattatccat taatattcgc
     5701 acctttcatt aagtaattta ttgaactaca tacaaaattt attgtttgct tacaataaat
     5761 accatcagca catataatca actccttata atattcgtct tttcaagtag tttatttcat
     5821 taaaacgtaa ctaagatata attttaatga ttatagtttg ttaaaaattt cattttgctt
     5881 ttaattgtat tttatcacat atttagtaat tatttgtcta tttaatacaa tttaattaaa
     5941 tttaagattt atttaaaaaa acaaagataa tccttacaga atataactca caatttgtaa
     6001 gcaatataca tataaggatt atccagatta tcttgtatta taaaatttta ttcaaacaga
     6061 ctttttaata actgacaaat acacactagc aataacttat caaagggtta ataattatgt
     6121 tactaactaa taagacttat tcaatcagta atatttatat agtttgtatc tattaagctt
     6181 ttatagcttc taataaatca tcaacgctat ctaatttttc tataagcatt ggaactattt
     6241 catgtaagtc tccaactact ccatagtcag cgatttctaa aattggagct gctgggtttt
     6301 tgtttatagc aattatgaaa tctgatgatt gcatacctgc taaatgttgt attgctcctg
     6361 atataccaca agctatatat aggtttggtt taacagtagt tcctgtttga cctacttggt
     6421 gagaatggtc tatccatcca gcatcaacag ccgcacgaga agaaccaact actccaccta
     6481 atttgtcagc taatttctta agcatttcaa atccttctgg tccacctaat cctagaccac
     6541 ctgatactat aacatttgca tctgtaagag atactaaatc tttcttagtt ttaactgttt
     6601 ctaaaacagt agttcttata tcatcttgag ttattttgta gtctaatgct ataacttcac
     6661 cagttcttgt ttcgtctttt tcagctttat ccataacacc aggtctaact gtagacattt
     6721 gaggtctatg gtttggacaa atgattgtag ccattatgtt tccaccaaat gctggacgag
     6781 tttgttttat tttcttatct tctgggtcta tttctaactt agtacagtca gctgttaatc
     6841 cagttccaac tcttgaagct attctaggtg ctaagtctct acctatatga gttgctccga
     6901 aaagcattat ttctggtttt atttcatcta ttgcatcttt tattactttt gtatatgcat
     6961 cagttgtata tttttctaaa agagcatcat ctgcaacata aactttgtca gctccaaaag
     7021 tgattaattc tttagctaat ccatcaacat cttttcctaa taatattgca caaagttctg
     7081 catctacttc tttagctaat tttcttcctt ctcctaataa ttctataact actggagcta
     7141 tttttccttc tctttgttct gcaaatatcc atacgttttt ataagaactt aaatctttta
     7201 tatcattcat agtttgtact cctccaactt atataatgtg cttttgtttt agaccgatta
     7261 ttattttact agctatttca tcagctttac cttctaagat ttctcctttt cctcttggtt
     7321 caggagtaaa tgatctaaat actttagttg gtgatgcttt taaaccaact tcttctttat
     7381 ttacatctaa atcatcaatt gtccaaactt ttacatcatg tttatatgct tttactattt
     7441 tatcaacaga catgtatcta ggtgtattta actcttttac tgctgttaaa agtacaggtg
     7501 tacttacttt tattaattcg tatccatctt ctaattgtct ttgaactatt atatcttttc
     7561 cttctatttt gaaatcttgt acatatgtaa cttgaggaat gtctaatttc tctgcaattt
     7621 gtggtccaac ttgtgcagta tctccatcta ttgcttgtct tcctgcaaat attatgtcat
     7681 agtcacctac tttagatatt cccgctgcaa tagtatttga tgtagcccaa gtatcagctc
     7741 ctccaaatgc tctatcactt aataatattg catcatcagc acccatagct aaacactctc
     7801 ttagcataaa gtctgcttga ggaggtccca ttgttataac tgttatagtt acatcatcat
     7861 gctcatcttt aatttttaaa gcttcctcta atgcatttgc atcatctggg tttaatatac
     7921 ttggaactcc atctcttata agagtacctg tttctttatt tattcttact tcgttagtat
     7981 ctggaacttg ttttacgcaa actaatattt tcaaagtcta tacctccaat ttcattagat
     8041 tatttattat tttaatacgt ttgatgaaat taccattttt tgaacttctg atgttccttc
     8101 gtatattgat acgattctag catctctgta cattctttcg atttcataat cttttataaa
     8161 tccatatcca ccgtgaagtt gtaatgcttt ataagcaact tcatttgcaa tttctgatgc
     8221 atagtattta gccatagcag attcttgagc aactctcatt cctgcatctc tcttttgtgc
     8281 tgcatcataa actaatcctc tagctgcaca aacttttgtt tccatgtcag ctatagtaaa
     8341 ttgagtattt tggaatttag ctataggctt accaaattga actctttgtt ttgtatattt
     8401 aacagcttca tctaaagcac cttgagctat tcctagagct aaggcagcaa cacctattct
     8461 accaacttct agagtaccca ttgctatctt aaatccttga ccttcttttc caagtaagtt
     8521 ttcttttgga actttaacgt tttcaaatat taagtcagaa gtttcagttc ctcttatacc
     8581 catcttatct tcatgagctc ctgttgagaa accatcccat ttactttcta ctataaacgc
     8641 tgatgttcct ctaagtcctt tacttctatc tgtaactgct attactatag ctacatcaca
     8701 gaatggtcca ttagttatga aagtttttct accatttaat atatagtggt ctccaactaa
     8761 ttctgctgtt gtttgttgtc cacctgcatc agaaccagct cctggctcag ttaaaccaaa
     8821 tgctcctatt aattcacctg ttgctatacc ttttaagtat ttttgttttt gctcttcagt
     8881 accattgtaa agtattggta atgaagcaag agaagaacca gctgtaacaa aagtagctgt
     8941 tgaagcacat cttctagcta tttcttccat tactatagcg taagaaacat atcctgctcc
     9001 cccaccacca tattcttctg ggatattact gcttataaat tttgcatcag ctaatttttt
     9061 gattaattcc ttaggcatta cacctgtttt atccatttct gctggtaaag tatctaattc
     9121 tttactaaca aaatctctta ctgcttttct taaaagttct tgttctttgt tatataacat
     9181 agcttcctcc aattttcata ttttatagta aatttatttt aatgaactta cgctaaactc
     9241 atcatctcag caaaagtttg aatacgagtt ctggcttgtt cattattctg agtttgttgg
     9301 tcgatttcaa catataaagt aggtattcca ctatcttcta tatcttttct aactaaagga
     9361 taatcgtatt cttctgggtc acagaatttc atcatacaga agataacacc atctatatct
     9421 ttctttttaa cttcatctac tataagtgac ccacgttttt tcttagggtc ataagctaat
     9481 gaacatcctt ctatgtttga ccattgtctt gctaatcttt ctaacgcatc atcacctgct
     9541 ggtacatctg ttctgaattg tcttgtttct tgtgctaagt cgtcagctac aactgatata
     9601 ttgttgtctt ctaaaatgtc taatatatct ttagaatcag ctaatatacc tgttaataaa
     9661 actttctttc cagaacagac ttcttctggc atagcattta attttgctat taaatctttc
     9721 actagctcag tatgttcttc ttttctcata aagaacccac tcttaattac taagcttctt
     9781 attgatggtt ttatagtatt agaatgttta taagctactt caacaaagtc tctcatagtt
     9841 tttctatgtt cattgtaaac ttctatactt tcatgaattt ttgcttcttc tatttcatat
     9901 ccacaaattt cttcaagttc tctttttacg cctttgtact cactgattaa gtattttaca
     9961 ccagcttcaa gttttctatt ttgtgggtgt actaatgata tatattttat atgaggtact
    10021 gctgatttcc agttttgtcc taaacaaatt agtgtatcac acatacctgg tataataact
    10081 ccagataatt catcataagc accttttaat ccatattcta aacatgattg cattattgaa
    10141 catgcaaatg cagggaaata ttgtttagct aaatctaatt ctgtttgccc tccccatata
    10201 ccaactggaa gcattccagc tgcatgtata atttcttctg ggcaataaac tgggaaacaa
    10261 cctatagctt ttttaccagt ttcactttta tattttttta cagccgcatt tggattttca
    10321 actacttctt tcattttaga taaaatagct tccattatat ctcacctcta ttaagttttt
    10381 ttctttcttc cattacttca actaaacctt gaattcttgt ttcaaattga gcattagtga
    10441 aagctctagg gtctgcttgg tcaccatcaa atccagcata tggtaatcca gtttcttcag
    10501 ctgctcttct ttgcatttca tattgtatta aactcataag tttacagctt ctgttcatat
    10561 gatagaatgc tccatcacat ttaccctcta ctaaagaatc aactctatat tttgtcatac
    10621 ggtctaggtt tacattgtta aacatagtac tatatgctac tgccattcca tctaaatcat
    10681 taacttcata ttgtaatgcc caagcatgtg ggtaaacact acctgtcatg ttaactccaa
    10741 atttagctaa tgttttcatc ttgtatccta tatatggcca acaaggtata ccttccatca
    10801 ttattctgta tttttcttcc cctctgaaag aagatttacc agttttcatg ttgtcctcta
    10861 attcttctat aagtaactta aatgcttctg tagtttcttt tttacctcta gcacaaacta
    10921 ttacagccat gtaagtaaat aagtcaaatc cattcattgg agaaggagaa gaatctgctg
    10981 gtaaactcat agaatacttc catagtcttc cgttttcagc tgatattttc attacttctt
    11041 caaacttctt agggtcaaat ttctttcctg atataatttc tagttgtttt atagcttctt
    11101 caaattgagc tttaatataa tctattcttg attgagtaac ttcgtcttca ttattgaaag
    11161 ttgtatcaat cattattaaa ggtatatcta attctcttga aatattttca taccatttta
    11221 taacttggtt acatatattg ttacagcaaa gtaggaaatc tggagctggc atatccaaag
    11281 cttcacatcc accattttct aaaagaccaa aatttgttct tgcatatgca cataggtcaa
    11341 tagaatatcc tttagattca gctatttcac ataattctaa agaacctttt ttagctgcta
    11401 ctccagctgc ttggttttct ggatataata cgtttaagtc aaatacttct gctaactctt
    11461 gaggaaatac tgatgttgac caacctacag gtcttccttc ttctttagct ttaaatgcat
    11521 ttgcatattg ttcagctaat aaatcattaa ttactactct agcttctttt ttttcagaca
    11581 ttttcatccc tctttttata tatttttcac ttctttttgt gattcttttg cttcatcaaa
    11641 agcatataac gctgctccta aagcaccagt taattgaggt atatcaggta caataatttc
    11701 tgtgttgatt tctcttgcca tagctcttac aataccacta tttctagcaa ctccaccaac
    11761 cataactaca tttctttgta ctcctattct ttttactagg ctagaaactc tctttgctac
    11821 tgaagtatga atacctgcca ctatatcttc aatttttgca ttttcagata aatgtgatat
    11881 aacctcagac tctgcaaata ctgtacatgt actgcttatt gatacttcat tttgagaatt
    11941 catagatata cttccgagtt cagatacatc aacctctatt atttttgcca ttacatctaa
    12001 aaatcttcct gtacctgcag cacatttgtc attcataaga aagtttaata gtcttccatt
    12061 attatctaat tttaatacct ttgcatcttg accacctatg tcaataatgg ttcttgtctc
    12121 tggaattatg aaatttaccc ctctagcatg acagcttaat tcacttattt gcttatcagc
    12181 atctgaatag ttcattcttc catatcctgt aactacaact tttttaatat cttctcttgc
    12241 aagacctgtc ttgccatata atttttctaa aactcttgat ggtccagtag tcccagtacc
    12301 agaggatatt gtttcagaag ctacaatatc ttccccattc tttaagatta ctccctttga
    12361 tgcagttgaa cctatatcta atcccattgt gtacatcttt agcattctcc ttttaaaaaa
    12421 tctagaatta ctaattaata tcttacaact ttactatctt taaagttatt tattttctct
    12481 tcatcgtagc ctaaagattt taatacttct acagtatgtt gacctacttt tggtgctggt
    12541 gtatattctt taattccttc atttctaaac ataactggag tattaactaa gacacctgta
    12601 tttccgctat cgtatgtttt cttaaataag aagtcatttg cccaagcttg ttcgtcatct
    12661 aataaatctt cacagctttg aattttttca aatggtaagt ctgcttcttc taataaagct
    12721 gaccactcgt ctaatgtttt ttctaacata gcttctccaa ctatcttaac taaatcttca
    12781 acatgattaa ccattgaatc tatgttatta tatctatcat cttctaatat atattctcta
    12841 tttataacct tacagaattt gcctaaccac ttgttgtatt gtattaaagc taattgaatc
    12901 catcttccat ctttacattt atatgtagtc attaatgggc tgtttggatt ttctcttgat
    12961 aaaggcattt catttccgta ttgtgctgtt gttatcattg ttcccattcc atatatagct
    13021 gtatggaaaa gacttactgt tactctctca cctttaccag tttgagcttt tttatgtaat
    13081 gctgctaaac ttcctgctgc tagtgctaga cctgcatagt ggtcaccaaa tcctgctgct
    13141 gtatttgctg gagatgttcc tttttccata acagattggc taactcctcc tcttgcgaag
    13201 tatgcagtat agtcaaatcc tggtttatct tttaaaggtc ctttttcacc atatcctaat
    13261 atttgagaga atattaatcc tggatactta tcttttattt ggtcataagc tatacccatt
    13321 ttttctaatg cttgaactct aacattagtt acaaatatgt ctgcttctga taataattta
    13381 tgtaatattt ctactccttc ttttgatttt acattaatac ttacaccctt tttatttcca
    13441 ttttctaatt caaacatagg gttttcatca tctgatgctg gagatttaaa tgttccaccc
    13501 ataactctta ttccatcacc ttctataggt tcaatcttaa taacctctgc accccagtca
    13561 cctaacattt ttgcacaaca tggtgctgcg atgaaacttg aaagttctac tactttaact
    13621 ccttctaaaa gcataacgtt ttcctcctta atagtatcaa ttataaaatt tcgattaaat
    13681 cactcataaa atactttttt ctgatattaa ctgtctgatg tcaaagttcc taatcttatc
    13741 taaaataact taaaaattat taaaattatt ttttattgtt ttattgtctt acacctatat
    13801 tgttaagcat ttatcgtgcc aactttatat ttaatcaaaa tatcgcttga tttgaatgtt
    13861 ttttaacaat atgcaattga ataatctttt tcatatcgtg gcatcttgcc actatccatt
    13921 gcattttgct attctttcta tgcttataaa agtttttttt atatattttt ttatgaaaaa
    13981 gcttgacatt tcaaaaaaag ttttcattgc taaactcaaa aacacatgtt atcattgtaa
    14041 ttaatcagca agttagttaa ctaatttcaa acttagataa ttttttaata atatttaatc
    14101 taaaaaataa caatttcttt gataaatttt agagtaatta ttacattaaa taaaaaatta
    14161 ctaaatatca aaataacaca gggaaaacaa tttcaaaact aaatttttaa ccttaaaaat
    14221 tttgtataaa aaatataacc ttatatgcta catattattt ctaaatgaaa aattaccata
    14281 ataatttaat aattacagga gggtattgat atgaaaatac tagtatttgg agcacgcgat
    14341 tatgaagaac cagtaataaa aaaatggtct gaagaacata aggatgttca agtggatatt
    14401 tatcctgaaa acatgactga agaaaatgta gttaaagcta aagggtatga tggtatatct
    14461 atacaacaaa ctaactatat agataatcct tatatttatg aaactttaaa agatgctggg
    14521 gttaaagtta tagcttcaag aactgcaggg gttgacatga tacattttga tttagttaat
    14581 gaaaatggac ttatcgttac aaacgttcct tcttattcac ctaatgcaat agctgaatta
    14641 gctgttactc aagctatgaa ccttttaaga aagactcctc tagtaaagaa aaaagtctgt
    14701 gaaggtgatt accgttggat agctgaactt cttggaacag aagttagatc tattacagtt
    14761 ggtgttatag gtacaggaaa aataggtgct acttctgcaa aattattcaa aggcctagga
    14821 gctaatgtaa ttgcatttga ccaatatcca aatagtgatt taaatgatat attaacttac
    14881 aaagattctt tagaagacct tctaaaagaa gctgacctta taacattaca tactccttta
    14941 cttgaaggaa caaaacatat gataaataaa gatactctag ctataatgaa ggatggagct
    15001 tacatagtaa atactggccg tggtggttta attaatacag gggatttaat agaagcacta
    15061 gagtcaggaa aaattagagc tgctgccctt gatacatttg aaactgaagg attgttctta
    15121 aacaaaaaaa tgaatcctgg agaattaact gacccagaaa taaataaact tctttctatg
    15181 gaacaagtta tattcactca tcaccttggt ttcttcacta gtacagcgat tgaaaatata
    15241 gtttattcta gtttaagtag tgctgtagaa gttataaaaa caggaactgc tactaataga
    15301 gtaaattagt attttataaa tatatttttt cattaattag ctattatcta acaaaatagc
    15361 ctttaatttc ccaaatataa gagagtcagc tcagtatata ttgagtagac tctcttatat
    15421 tattttttat attaaacttg tactcttctt attcatacca aattaaattt atattaactt
    15481 attctaacta ctcctactct atacatttta cctattttta cttttctaat tatatacatt
    15541 tgaatgggta caatctgtat tttacaaaaa aaacacctaa caaactatga aaattgtatg
    15601 attaatatta atatatttat aagaaaacat aacaattatg ttagctctgg atttttaggg
    15661 agggagtata ttggaaaaaa tgaataaagt tacttctaaa aaaactacct atattgttac
    15721 ttcagcatta tttgcatcca taatatgcct gacaatagca tatatattac atattccagt
    15781 tggtggaaac aatggatatg ttcatatagg agatgctttt atttatctag ctgcaactat
    15841 tttgccaaca aactatgcta tagctgcttc tgcaattggt gctggtctag ctgatttatc
    15901 tacaggtgct gctatctggg taataccaac tataatcata aaaccaatac ttgtattatt
    15961 tttcacttct aaaagtgaca agataataaa taagagaaat atagttgctt cggttgtagc
    16021 aggtatagta ggattagttt tatacatgtt tgctgaaggt ataattattg gaagttttac
    16081 aagtgcattt gtaatgagct tacttggctt attacagcca ataggaagtt ttattgtttt
    16141 tataatctta ggtatggcac ttgataaact tgattttaaa aaacgttatt ttaattaaga
    16201 atttaaattt atggagggaa aattatgaat atcttatata caattgaaaa tagtatctat
    16261 gtaaatataa ctaatacatg tccatgtagt tgtgtttttt gtataagaaa cgaaaaagat
    16321 gaagttgcaa atagtggtag tttatggttg gagcatgagc caagtgtaga tgaagtaaaa
    16381 gaagccttca ataaatacaa tttagacgac tatgatgaaa tcgtattttg tggatatggc
    16441 gaaccattaa tgagaataaa tgaattgata gagatagcaa agtttataaa agaaaaaagt
    16501 agcataaaga taagaataaa tacaaatggt ctaagtgatt taatacataa caaaaaaaca
    16561 gctattctgt taaaaaatgt tatagatgca gtatcaataa gtcttaatgc cccaaataaa
    16621 gaagcttata atagagttac tcaaccaaag tttggagaaa aatcatttga ttatatgtta
    16681 gattttgcaa gagattgcaa aaaatatata aaagaagtag ctttttcagt agtagatgaa
    16741 atatctccag aagaaataga agaatctaaa caactggcaa aaaaacttga tataccatta
    16801 agagttagac ataagaatta gcaagtaaaa ttataaaaca ttaagaatca cctgaatggt
    16861 atttcaggtg attcttcctc ttgtattaac attttacaaa atagatttca taccacacta
    16921 ggaatgtgta aatcatccaa atctttctcc aattatcaga gtttccacta atgtagtcat
    16981 taaaaatctc attaatctca tctatgttaa agaatttatc tgctatctca ctattgaatt
    17041 tatctcggat atccttatta tatcggtcat cagccatcca tatacgaatt ggcacaataa
    17101 atcctaattt atttctaaaa gcaatctctt ctggtaatgt ttttgatgca gctgtacgaa
    17161 aggcaatttt attctctttt cctttcactt tatattctga tggtattctg gatgcaatat
    17221 caaatattct tgtatctgta agaggcattc tgacttccaa tcctactgca gtactcattt
    17281 tatctatatt aaaataaata tctccttcca accatatttg aatatctaca tttgacatgt
    17341 tagtaagtgt atctagttct tctgtttctt cataaattcc ttttaccact tcaataggaa
    17401 gcacatcagg attgtatttc ttaagaattt ttcttttctc accctcattc ataatgtttg
    17461 tatttccaat ataaaatgtc ttcaaattct ctccataaca ctctgcctta tggtatatat
    17521 tatatccacc aaaaaactca tctgctcctt ctccagagta acagatattt gtgttttcag
    17581 ctgctgcctt gcatccaata gcaaaaacga tagcagatgc atctccagtt ggttgctcca
    17641 tatggtacat tacataaggt actgacgcaa aatactcttc aggtgtaatt atatatctcg
    17701 aatttttaca cccaagaata ttagctgtct gttgtgctaa ttttgattca tcaaaacgct
    17761 cttcctcata accacatgaa cctgtttttt ctatatctga cattgccaat atataagatg
    17821 aatcaacacc tcctgatagg aataactctg cagtttcatt ctctgatttt acctctggca
    17881 taattttctg aagtgttgta tgaatttcat ccgtccattc ctcaatagac ttgctgtggt
    17941 caggatgaaa ttcaggtttc caataacgac caatacatac tgttttattc tgatagacaa
    18001 ggtaatgtcc tggcataagc ttctttactc cacggaagaa tgtattttca cctgctacat
    18061 atgtgaaaga catataaatc tgtaacatgt cttcatttaa ctctttcaca aatcctggtt
    18121 gctccataat cttacgaata gatgaaccat agagaagctt cccattttca gtctcataat
    18181 aatagaaagg ttttacccca aactggtctc ttaggcagaa gagtttcttt tccacagtat
    18241 cccataatgc aaaagcaaac attccatgca tgtgatttgc catatcatat ccccatgtct
    18301 tatatgcttc cactaaaatt gctcgttcac gctcatctct acataatgaa gaatcgattc
    18361 caagttcttc acaaagaact ttccagtttc gaatatgccc attgtattct agaattttta
    18421 tcatatatgt gtcttttcgt gttaaatact tttcttctaa atttatcata tgtgtatcct
    18481 ttcgtattaa aacatttaac ttctaaattt attaaatgtt tatatatatt tattcactta
    18541 taatcactga aaaatcgact tttttcaaag taaattcttt ttgaattagt actaatctgc
    18601 tctttattaa tggcataaat atgattatca agtattatca gtgttataac attgaatttt
    18661 ttattcttca taaatattgc cccctttata ttaccaacta aatataatat atcttatgtt
    18721 acttacatat tctttaagaa attctgaaga ttttataaag ttttttgtat tataattaat
    18781 taaaaataaa attctagtta taaaacatat tttccattaa acaaaaaaat agttaaaata
    18841 aattcataac cacataaact tattttaact atttgtatat tttaattata aatattaact
    18901 taaattttta acaggataca ctcataaaat aaacataatg aacaacaaaa taatatgtct
    18961 cagtttcttt atatacttta ccttctttca attttctacc atgtagacgt ataagataat
    19021 attagtaatt cactctattg cttaactcgt gcgatatgta caaccaagaa agctatttcc
    19081 tcatttgtta acttttttcc atatttcttt tctaaaaaat ctctaacttt taatgcaatt
    19141 aacatttctt ttggatttga ccttttcatt tgattaaata ataaatcatc accactgctt
    19201 aacatactat ctgaaaaaaa tctttccaca aaaaatttta tatgtgttat aaatctcata
    19261 taatgcatac tctttttatc taaggttcta ttcaaagaaa aaacaaaaat attaattatt
    19321 tctccaatta ctttggcata cttaatcgta tcatatgaat ttccatctga agccatagca
    19381 tttgcaaaat ggaaagcaat gttagctgct tcttcctctg gtaattgaat gcccaatctc
    19441 tcctctacca tataaattgc aaccattcca accttaaact catttggata ataatttttt
    19501 atttcccaaa atactcgatt tgtaattttt attcctttac gcatcctttc aattgcaaag
    19561 ttaaaatggt ctgctaatat taagtataag tttttattaa aagatgagtt caataacttt
    19621 tctgcctcta ctattatttc ctgtgttatc tttaaaatgt cgacaggaat atcatccatt
    19681 aattctaaaa attgttttga ttttgtattt tcaacaggga caaacatttg attatcattg
    19741 gaaccacaaa tatattctcc tgttttttta ccatatccaa ttcctttccc tagcaaaata
    19801 aattcattat actttgcatc atgaactaaa acaacgctcg agttcaaaac tttctttatt
    19861 atgtagttca ttttatttgc tcaccttcta ttggtcattt aaaatctata ctattatttt
    19921 caattacctt tttataccaa taaaaactat ctttcttata tcgattatat gtcccctttc
    19981 catagtcatc agcatccaca taaatatatc cataacgttt tgacatttgt ttcgttgatt
    20041 cactgaccaa atcaatacaa ccccatgaag tatatcccca aagttcaacg ccatcttcga
    20101 taatcgcatc taacatacat ttaaagtgtt cttttaaata attaattcta tattggtcat
    20161 gaactttttt atcttcagtt aaaatatctt tagctcccaa tccattttca actataaata
    20221 aaggctttct gtatctatca tataattcaa tcaaagatat acgtagacct attgaatcaa
    20281 tttgccaacc ccattcactc atttctaaat aaggattttt tacagctaat aacgtattcc
    20341 caggtgtaat atctaatcca gttgtatcag ctgcctcaca agaagacata tagtaagaga
    20401 atgaaataaa atctactgga tactttttca taatttcatc atcatgttct tcttttacta
    20461 tttgaatgtt attattttta aaatacgaca gtaaatatac tggatactca ccaaaaacct
    20521 gcgtatcact atatgcataa atacttctca ttttttgttg agttgccaaa acatcttctg
    20581 gtctacatgt atatggataa tacgttaatt ttgttaacat acaccctact tttgaatttg
    20641 gaataatctc atggcaaatt tttgttgcaa tggcactagc tacaaattga tgatgcatag
    20701 cttgaaaaat aacttcctca aagtttttat ccttaaaacg gtctcgaact aaaccaccag
    20761 tagtgtacgg atgacgaatc atagaatcaa cttcattaaa tgtaagccaa tatttcactt
    20821 tgtttttata tctttcacag atagtttcta catacctaac aaacatattg ataacttgtc
    20881 gtgaatacca tccatcatag tttaaaacga tatttaatgg tggttcataa tgtgacatag
    20941 taacaagtgg ttcaattcca taacttatca actcatcaaa tacatcatca taaaactgta
    21001 aaccttcttc atttggctct ttatcatctc catttggaaa aatacgagac caagcaatac
    21061 tcattcgata tgtcttaaat cccatttctg ccattagagc aatatcttct ttatagtgat
    21121 gataaaaatc actaccatga cgttttggat aatttacttc atcttcagga tgtgctaatc
    21181 cttcttctat atcttttgtt gtgatttcat tattagattt ataatctttc acatctgcat
    21241 caaagtgtgc ctttgctaca tctgatacag accacccttt cccacctaaa ttccaaccac
    21301 cttcaaattg attagcagct gtagctcctc cccaaagaaa tccttctgga aattttctca
    21361 tatttatatt cctcccttta catcaaacaa gatacttcct ttttttacat tgccataaga
    21421 ctggtttaac actttataag cataatctgc tccattattg tttacaatca taacagttga
    21481 atctaaatta gcatgtgaga ttttgtctaa atcaaattga attaataaat ctccttcttt
    21541 tacattatcg cctgtcttaa caaatgtttt aaatccatct ccattcatac ttacagtatt
    21601 tattccaata tgaatcaaaa tctcagcccc attttttgtt cttaaaccaa ttgcatgttt
    21661 tgtttcaaat aacatcacaa cttctgaatc acaaggtgcg tataaatttc cattggttgg
    21721 tataattgca actccatctc ccaaagtctt acttgcaaat agttcatcat taaccttact
    21781 taaatctatt acttttcctt ctactggagt tactaagata tttacttctt tttcttcttc
    21841 tagctcttct tcaacaacat ctccaattga tgactctact gtatttgtat cttccttcca
    21901 aataatcagt gtaataataa acgagcctaa tattgcaata acaaaaccaa tactcgcaaa
    21961 aatcaaattg tttccattgt ttgggtcaat aaacatactc atactggcaa gccctggtcc
    22021 aacaattaca aatcctttta ctgcaaataa tcctaaaaag gtaccagaaa ttgcacttga
    22081 gaatacaaca cctaacattg ctcttttatg ttgtaaggta ataccatata aagctggctc
    22141 tgtaattccc atcaaggcag aaattcctgc agataatgct gtttgtttta atgtttcatc
    22201 ttttgttcgc aaggctactg caaaacaagc accactttca gaaatattgt gggctaatga
    22261 agatgtcata tataaagctt cataacccaa ctttccaatt gtattaattg aataaggtat
    22321 tagtgctttg tgcattcctg ttgcaaccat aaatggaaga aaagcagcaa gtaatcctac
    22381 aactaagaat cccattttgt tatataagaa taaaataatg gttgtaaaaa ttgtaccaac
    22441 gttatatcct aaaggaccta aaatagttag agtaattgga acagtaattg ccaaagacat
    22501 cataggaaca aagaaagttc gaattggttt tggtgaatac ttgttaaaaa ttttctccat
    22561 tgttgccaag aaagacacac ataagatagc cgggaaaacc tgtgcattat aggcaatgtt
    22621 tggaattgta aatccaaata gttcaacacc ttcacttaaa gcagttgttg ttgctggaag
    22681 caataagtat cctacagcgg caatagctac taaacgatta catttcaata cattggcagt
    22741 agttacagct accataagag gtaggaaata gaatgttgca tctgaaatag caactaataa
    22801 tgtatatata gtagaatctg attttaaaat attaaacatt gctaataaca tcaacagtga
    22861 ttttaaaata ccagctcctg caatagcaaa aatcagtggt tgaaaaatat taataataaa
    22921 ttctataaat cttgttccta agtttatttt ttcttcagtt tttacagtac tatcatttgt
    22981 atctaaaggg caaactttta aaatttcatc atacacatca acaacactat ttccaatgac
    23041 aacttgaaat tgtgccccat taactatact cataacacct tgtacttttt ttaaagcatc
    23101 ttgattgact ttacttctat caatcaactt aaagcgtagt ctagttgaac agtgttctaa
    23161 agctaaaata ttttttgaac caccaacttg ttcaataatg tcaatggcag tttttttata
    23221 attcatcttg taatctcctt ctccataatt ttttatgaat ggccattcaa gatgcaaaaa
    23281 aggcagaacc tatataaaca ccttgaaaaa tcaaagcaat atattcgatc ctgcctgcat
    23341 taccagtaac atgtcttcta tttatactat tttgtattat tatattaaca tttgcctaaa
    23401 agaattgtca atactttttt aaattttctg atactaacta atagcacctt tataattcat
    23461 tttttatgtc aattaaagta acagtagcca cccaccaatt agtatcaaaa ttgaacctgg
    23521 tattttttct tttatatttt ctttgaatat aaaatgagca agtattaaag ttattatcat
    23581 agatacttga gaaaatggct ctgctatact aagttctaga ttatttaaag caattaataa
    23641 tgctaaataa gaatatccat taatagcacc acttaaaatt gaaagcccct ttttattagt
    23701 aaaaatctca caaattattt tttgtttctt tttaaatgct aaaaagataa ataaatttaa
    23761 acctacgaaa aaatacagta tagttgaata taatatagga gatacttgta caaaaaaagc
    23821 cttatccaat actcttccta ctgactgcaa aaatatgtat aaaaacatta atctacatgg
    23881 taaattgtta aaaattacag agacattctt taaaaaagaa cttacttttt ttaatataaa
    23941 cactccacca atcataatta tgattcctgc aacttttgct aaacttaaac cttcacctaa
    24001 aaatataact gataaaagca gtaaaaacaa tgaatttaaa ctatttattg gagtaacaag
    24061 tgaaacttcc ccagttgcta aagacgttac atacgctact gaaccaattg aatagactaa
    24121 actacttata taacatggta ttaaaaacga ccaatcacta actctatcca ttatgctaaa
    24181 tggaagtaaa catactcccc ctataaagaa aaatagaaat gatgaagcta tatttttata
    24241 aatatctcct tcttcatcac ctaataatct tacaactact ctttcaaaag ctaatagcac
    24301 tactctaatt aataatgcaa aataagataa tatcattttt gacctcgctt aaaaattaat
    24361 ccgacttatt gttatattaa ctgtataaga ctaccatata ggtaagtctt ttggattttt
    24421 taatatttta tgtttaaata caggtacatt aagtttttca cctagtttac ggcattgctc
    24481 tttataggta ccttttaatt tatcatgaaa aactatacaa tcaattcctc cttcaatgct
    24541 atttatacac ttttctagtt tctcaaatcc agattcatca tcatacattc cacttacaat
    24601 ccattgattt ggcaatacat gtccaattga tatgttatat tctttatttt ttataatatc
    24661 tgagaaagat ttctcaaaat gtacccctcc aacacataac aaagtcttca aaggttcatc
    24721 acaatcaaat actctaatta atgattttgc caatacctgt attgctatac tattattaaa
    24781 actatcacta ctacttccta tctcaatatc caacataggt acagaatatt ctgtaattaa
    24841 tttagattct tcaccatatg ttgttccaga ccagtgagtt gcttctgtta atgtagtaaa
    24901 ttcatcaagt agattttcat tttttatatc ctcaatagca ttgattagat ttttaaagta
    24961 tcttggattt gaatttccaa attctcctgt tggaacatct ccaattgtat gagctgttag
    25021 gatatgttct ggagcatttt ctccctcatg ccaatttaca actcctgcaa aatcataatc
    25081 tctaaaatgt ctatttaaaa ttggaagata atatttataa ttatgactta ttacatcttt
    25141 tgtttttaca aaatgaaata agttattgtt tttatcctta aactctaata caaaattatc
    25201 atcaataaca atatcagttt gatttaaatc cattatttct tcacaacatt ttatcacatt
    25261 actggctact gggtctttct ttaaatcact gcaaaagaaa aaaactgctt ttttattatt
    25321 catccataaa tcacactcct ataacttaaa tataatatat cttcatacct aaaatcatct
    25381 aaatatcact ctaattccat taaattattt atatataata tactaccata ctcattttag
    25441 ctataccttt gcctgagttt ctatatatat gtgatacatc agctttaaat cttatagaat
    25501 ttccactaga tacaatgtaa tcttctccat ttattttaat ggttacttcg ccactaaaaa
    25561 cagttataaa ctcttgtgtt cctggaagtt cagcatttga atctaaattt ccaccttctt
    25621 ctatttcaat cataaatatc tcaaatcttc ttttggagtc aaatggaaat attggataac
    25681 ttatatactt tccattatct tcaataaaat ggtctatatc acttttttga atcaattcta
    25741 tgtcactttc ctgcctctcc atcaatgatg taaatgaaat ttttagccca ttagttattt
    25801 tcttcaaagt agatatagta ggatttacct cacacttttc aatttgagat agcatactct
    25861 tacttacacc actaagttgt gcaatcttgt ctaaactaag atgtttttct ttccttatct
    25921 tttttaaatt ttcagcaatt atttcattta aactttgcat aaataccccc taatacatac
    25981 taatataaga taaattattt tgattattaa ataaacttag taatttaata gaaacttttt
    26041 atccattata atgtacatta tgtttaatat acattacttt ttttagaatg taaatagttt
    26101 tctgaaattt tgtgaaaatg aataaataaa aaactagtaa cctatatttt tacaaggtta
    26161 ctagctttta ttataataat atttcatttt aactataaaa cttagatgca cctataagct
    26221 gtctcttaga aacaatctta gctaggtttg ctaatgaaga aatttttata tctttaaaag
    26281 aaactaaaaa tacaaactta aaatctgtaa attcttgatt tatattgtat atatcaaaat
    26341 aacatctcaa attatcaaat aagtaattat cctgtaagtc tgcttctatc tcatcagtag
    26401 catcttttaa atacgctctt acatcttcaa ataaaacact gaaataagac tcatctattt
    26461 cttcacctaa ctcttccaat atttcttcta tatctaaatc atccatatca aaagaatttc
    26521 ctgtcaactg gcaatcaaat accaatatat tttcttgatt tatagtattt gatatatctt
    26581 gtacatattc gaagtctgga cgtaattcta aaatgtcttt tatttcactg ctctttacat
    26641 ggatttttcc ttttctattt tcaattttta aatctatcat atgctccccc tttcaatcta
    26701 caaatcttta aataccttgt tttataatct tttcaatatc tatccaatta ctaactctaa
    26761 ctatattttg atgtttaaca tctttattat agttagtatc cagaagtatt actttaacac
    26821 catcatcagc tagttgcact gagtttaaag gattatcttc tataaatatg tcacaactca
    26881 gttctcttgc cttttcaact ttataatcac ttcctaataa gtaaacatct atatctgaaa
    26941 atccttgtct cgatagccaa tttttagtta catcagttaa acactcatgt ctagccgtta
    27001 caaaagataa attatgtcct ttagataatg tgctaattac ctctgtagca ccctctacaa
    27061 tctttgcttc atcatatgag tgtatatact tattattaaa ctccgcatac acatctctta
    27121 ttcccgaacc atacaattct tcccaattat gtgttataca ctctgcttca gttatatttt
    27181 tattaaagat atcatttagg tatggaagaa aatgataagg gcttgttatt gttccatcta
    27241 tatcaataca tatattcaat ttgttcattt ttacctccat gtaacattta ttgatttgat
    27301 taatcaaata ttatagcaca gctttaatta taaatcaaaa ctctggatat gactatacct
    27361 atataatacc aaaaagcttg catatttaag caagcttttc gtaaatttta catttttaac
    27421 taatatataa gtttttctaa ggttggttcc actccaaatt gtgatttcag ttctttatat
    27481 tcttttaatg ctttgtcatt attcgtttta gtttttatcg ctcttatcat taaatttttt
    27541 ggtgtatcaa gtggagatat gtattctact acagaagtat catatccatt gccctccaat
    27601 aacaatgttc ttaaaccatc agttattaaa tctgcaaatc tagctttaaa tacaccatgt
    27661 tttaatattg gttccatagc ttcatatcta tattgcccta ataactcctt atgacaacat
    27721 ggtactacta ctatagcttc agattttgct ctaattccta gacctattgc catatctgta
    27781 gctgtatcac aagcatgtag acttattaca aggtcaacat ccctattagg tgtataatta
    27841 gtcaaatcct cttttataaa tgacatattt ttataaccca agtttttagc catatttttt
    27901 gatgcttcta taactacatc tgaataatct attcctataa aataacagtt tttcttcaat
    27961 acttctttta tataaaaatt taagacaaag cttaagtaag attttccaca agcacaatcc
    28021 aagatagtta tacagtcttt atcctttatt tcttttaaaa tactatctat caattcaaca
    28081 aaatggtcta tctgattgta ttttcttatt ttatcatttt ttatcttacc atcttttgta
    28141 agtactccaa tttcttttaa aagtgcattt gcttgtccta cttttacata ataatctctg
    28201 ttttttattt gagatgccgt aaattcatct attttaggta cttcttcctt attatctaaa
    28261 tattttacat ttaccttctt attgtctcct tcaattacaa caatagttcc tcgctcaaca
    28321 tatttaaata ctaatccatc ataattttct gcctctttag aaatattctt aagcaactca
    28381 ttaaacgtat ataaatctga ttttccttta aaattaaatt tatatttatt atcttcctct
    28441 attgcaattc ctttaaactc ttttcttcca gatttaaaaa tcacctctaa ctcaataaaa
    28501 aaatccctat tatcaaggtt tctttgagta atccccataa aaaacatatt tagttttcct
    28561 atactctgtt tattcatcat aatctccctt ttaacttata tctttaaatc ttattaatta
    28621 atattatttg tttctgaatt atttatttct tcttttaaat cgttcaatct atttttaaaa
    28681 ctttctatct gcttatctga taaatcaaga tattctgtta tcttccctat atatttaggg
    28741 cttttagtat ttattaattt caaagcactt tccatagatt tttctctaag ctcatatgct
    28801 ttctttacgt catctctagc attactcaat gtttctgtat acttctcctt agaaagttct
    28861 ggaatctgca tattttcata ttcttttaca acttctttac acttgtttct ggcatttgta
    28921 acatcttttt ttatactaga taatttagtt atattttttg ctatatcctt agtgtaaggt
    28981 atacattctc tcattggaac taaagctgct ctttctatat tataaatttc tttcttaaaa
    29041 attcctatac tttccatatc tatttttttt atatcttcac tatttttttc tttacttgta
    29101 tatttattat tttcttttgt attatcttct tgtttttctg atttattatt cactgaaaca
    29161 ttactatcag aattattctt ttcttttata tcattacttc cttcttcatt actttcttta
    29221 ttttgtatat ttctatcttg tttgttgttt aaatttttat tatttgatat ttcttcattc
    29281 tttttattat cctgttttaa atcagtactt tctttttcct taaaatttga tacatacttt
    29341 tcatcatatg tctcatcaga aatataattg tgataataca tagactcttt tattttatta
    29401 agtccactca tataaatatt acttatcatt attgttgtag ctaataccac ataaatacta
    29461 ctgtagatac aagacctctt aaaattcttg taatttctga atatcactac taaaggaata
    29521 agatataaaa atataaaaac taatatccac ctcataagtc gtgtctcctt tctcaaaacc
    29581 gaaatccctc aaatatttat ttttaatcat gtatcttata gtatttacca atttatgttt
    29641 tttaatcgtg aacttttatt aaattaaatt ctgtatagtc acaagatgct aatgtatatt
    29701 ctactccatt tcgaatcccc ttcaatccca ttttaaaaga ttctttacca tgcaagtgac
    29761 cataaatcac cttttcaaca ttatattctt caaataactt tgtaaataaa gattcttcca
    29821 atttatcatt cgtaggagga taatgagtaa tcacaattat ttttgagtga ccacttttac
    29881 gagcagattc taatgatagt ctaagtctat gttcttctct tttataaact ttttcatcag
    29941 tctcatcaaa tttaacatca ttaggacata tccagcccct acctccacaa attgcataat
    30001 ctttatattc ataaaaattt gtctgaataa aacgcatgtc ttcatatagc ttatttaaac
    30061 ttgtaacggt tgtccaccag taatcatgat ttccctttat aagtattttc tgacctggaa
    30121 gtttgcttat tatatctaaa tcttttttag cttcggataa attaattccc caagatgtat
    30181 ctcctagtac taagaccata tcttcttcct taacaacttc tttccaatta tctataattt
    30241 tcttttcatg accatcccaa ttacttccaa agatattcat tggcttattg actgatgttg
    30301 aaaaatgtaa atcacctata gcatacaaac tcataatatc attcctttct taattacact
    30361 aaataggctg tctcttttta gaaattattt tccattaaga ggcagcccca ttaatattta
    30421 gcaaattttc tacaagtagt ttttactgaa ctactttatc atctacctta gtatccttat
    30481 attgctctaa taatatatct atttcttgtt ttaattccaa aatttcagtt atatttttat
    30541 ctgtttcagt tctatcaagt tttctttggt actgcatagc tttatgtgta tcacccaagt
    30601 catataactc ttgtattcta tttaaagtat ctctaatagc tatagacttc atttggtaca
    30661 tagcctgagc tttcattatg tcctctctta tttcactcat ttcttggtct aaaagaaagg
    30721 cagcatcaga tgctcttcta agcctttcag caagagtctc aggtatgtaa tggtcatatt
    30781 tatattttaa tgaatgttct attgtagccc agaaattcat tgcaagagtt cttatttgta
    30841 tttcacatat aatttccttt gaacccgcaa tggagtttat agggtatttt attataacat
    30901 gatagcttct ataaccacta tctttgtaat ttgtaatata atctttttct cctattatag
    30961 tcatatcatt tcttactttt atcaaatcaa ctatagcata tatatcctca acaaactggc
    31021 acattattct tataccagca atatcatcaa tttcagtttc tatatctttt gcatttatcc
    31081 tttttaactt agatattatg gaagatattt tttttgttct acctgtgaca aactctatgg
    31141 gagaatattc accttttgct aaatattctt ttcttatatt tttaaatttt attttcaatt
    31201 cctctactgc atgttcataa ggtgctagta tctcattcca tttttcgtat tccatattgc
    31261 tcacccttta tttgtttttt atgaccttct ttattttatc ataatttatt ttgtttttgt
    31321 atagtaaagc aattctccat tttccaatat ataccctatt tcttctaaat caactaagta
    31381 acttatgaca gatactaacg aagatttaaa aaaatgatac tctttataat tattgcttaa
    31441 attattgtta tttataatgt tttttaataa aatttctaaa gatttcggtt ctacaagcaa
    31501 ctctcttatt tgatataaat atttttttaa agcattcaaa tgtttttcta ttaatttata
    31561 agaatcttct ttcgatataa cttgcttgcc atgccctaaa actaagtact caaaatctat
    31621 attttttaat ttttctaatg aatttatttg ttcttgtata tcatatagaa acaagaaatc
    31681 gtattttgat agaatttcat ctcctatcaa taaatcgcca acaaaaatca cattatcctt
    31741 cgtcaaaaca gctatactac caggtgtatg accctgaaat tcaattatat caaacatttc
    31801 attgtttaat tcaatttttc cagcttctat agatttatct atttttatat catccaacat
    31861 tttatttttt aagatattat ccataaatac attgctcttt cccccaacaa tatactttga
    31921 aaacaattct ggattttcta tatataattt atcgtattca gatgacatta tacacacatc
    31981 tttataatat tctttaaatt gattacaagc tccatagtgg tcatcatgac catgagtatt
    32041 tataatatat ctaacctgta tattattttc atctaatact ttatttactc tcctaggtct
    32101 tgaaccacat aaccctgggt ctatcataag tgctgtgtta tcttcaaata catatattcc
    32161 tgtattcgtg ccacctttta taaaaaaggt atttcctttt acttttgtaa gattcacctt
    32221 cttcacctca ttttgacaat atttatgata caatttatta cttactaata taaaactata
    32281 caagaacaat cctttttatt ctatctatag ttctttttct tattttgtat tctttagata
    32341 tccttatttt cacattatat gctaaatttc tataaagtaa tgactctata aaatattcaa
    32401 ctatacctct atccctaaag tctatatcta tatttccact tgaataaata tttgagtcta
    32461 atatcataag ctcatcaaaa aagcttaatc tcttagattt acttaaataa tctttatttg
    32521 gaataaatct atcacaataa tctatcctgt aatttactac ttcatcattt atttcaaatc
    32581 catattgctt tttcattaac tctctatagt tattattttt ctcaataaca ttatctaaat
    32641 ttttattata atcctctttt ttccaatgtc caaacatcct acaatttaat ggtctaactt
    32701 catatattaa acatctatta ttagtatctt taaatggaca tgggttcttt cttgtatact
    32761 cctcaaaata ataatctaat attttactta tacagctttt ttttaaatca actctatctt
    32821 caagataaca aaatatattc aagaactcaa ttaaatttat acctactgac tccatacaac
    32881 aatttccaca tccagaacaa tttcctactg gcaaggactt atatacatca tttagtttgt
    32941 caaagagctt atttttaatg gaataatcta tacaatttaa aatatcttta ttttttatac
    33001 tagtcattat tattactcct tgttataatt attaagttaa tacaaacaat tattataaca
    33061 tattttttaa atttaatcgc atatggaggt attttatgaa tagatataca aaaataatta
    33121 atatgatggg aagttattac acaaaagact ttgaaaaaga aaaaaagaat gtaataaaag
    33181 ttagagaagt taaagaagat acagttagaa aatttttctt acaaggtgac tgtgaagttc
    33241 ttgtagtatt tgaagacact gggaaagaaa tacttattga tgacttttct cctgaagaag
    33301 atatcaaaaa atatttagga gcaaaattta taaataaaaa aagatagtta tcaaaaataa
    33361 ttctaaaatt aaaatttaat aaatgtacag ttataattct atataattat agttaaaagt
    33421 tatcttttat tgctttttta gactttaaga tagctttttt tctatttttt gtaaaataat
    33481 tccataattc acattaataa ttcacaaaat gatataatat aacaaataga taaattttta
    33541 aatttctaaa tacataatta atattttgcg aggtgatttt atgcaaattt attttagagt
    33601 taaggctgtt ggcaaacgca aacctatgct agaacttacc ccttttgata tatctgacaa
    33661 catcaattgc ctaaaagaag ctatctctga aattgtatct aaaaatgttc ttgaatataa
    33721 tgagaaaatc ccagaaaaat caataataaa cttcttaact aatgaagaaa ttgaatctca
    33781 agctgatatt ggaaaagttg gatttggctc tatttacaat gagaataaac aatctgtaga
    33841 aaaggcaata gaggtagcgt tacaggcatt tgaagatgga atctacaaag tgcttataaa
    33901 tgaggatgtt attgaaaaac tcgattcctc tataaatctg aaaagtggag atatatttac
    33961 ttttataaga cttaccttgc ttgctggaag aatgttttaa aataaataat ttggaggtac
    34021 ataaatgtta gaacgtacta gagtagaaaa aaatcctaaa ataattgaaa attttaaaaa
    34081 taattttact aaatcttctt caaaacagta ctacgactta gcaaagtctc tttgggactg
    34141 catagaaaat agttcatact attatagaga acctgaagac aaattcttaa atatgataaa
    34201 gaaatactac aattgccact actacgaaat taaaaatatg gacgagctcc tttctggacc
    34261 tttaaaaaat gcattagaat taatatttac ttctgaacaa gtagaagaac tttgccaatt
    34321 aattaaaaga aagatggatt atacatattc aggaggatat tatcgtaaag ggtatcgctc
    34381 aaataaactt gtggattatt ttagaggtat tataaggttt atttcaaact atgttgattt
    34441 aatttattat gatttttcag ttatagatta tcttactctt ccaaataagg tcttgtacta
    34501 tgactctata atgagtgata aaatagcact agaaatagac aaaggaaatc aaaaagtaat
    34561 aagtgcttta gaagaagtaa tatttggaga aaatcaaact gctctactta caagacaaat
    34621 gataattggt atcatgaaga gtcatagtga taaatgctat gaaatgcttt ctaaacttct
    34681 tttggcagcc aaacaacaag aaggacttag acagcaaatt gtagagagtt tagatgaggg
    34741 tacaatttct gcatcaatat acatgttaaa aactattttg gacaacaatt tagagcgatt
    34801 tagttctgtt ataagagcct tggatacatg gacaggactt ggtttttcag accaaaaacc
    34861 tggaataata cgtaaatgtt tagaactttc atataaatca ttgactgatg aaaagttccg
    34921 tatagaatca attaatagca atgataatct tgaaatttat tttgccttat gggctactgc
    34981 aacttacaac atatatgact cttactctct tattgaaaac ttactttctt gtcaggaaaa
    35041 atataaaaaa cttgtagctc tttacttttt atcgcataca gaaagtacat attttaaaca
    35101 ttctatagca tctaaaaaca ttaagggtga tgatttagag atactagcat gggtaattac
    35161 aaatttctat gtagaaggtt ctgttggcta ctactatagt tggcaaaaca gagaaactaa
    35221 ttttgacttg tcaaacactc ctattgacaa agactttgat gctagaaaag aacaatttga
    35281 aagtttaaaa catactttag aaattttaaa ttcaaagaca aaatcatttt caggaagtgt
    35341 atttccatgg acttggattg aaatttcttc tcatgaaata cttaaatgta tgatgacttt
    35401 aacagcatac gatatgaatg ctcaatttat agatgtgctt atggaaaatt gtcatcttat
    35461 gagttcagat ttaagagctt cacttatagt caattttgta aatgaaccaa agacagatag
    35521 acaacgtgaa tttttattgg aatgtttaag tgataagagt gtttccaata gagaaacggt
    35581 attgagtcta cttagaaagc ttgagctaac agatgtagaa ttagataaga taaccaatct
    35641 attgtcttta aagacaagct ctattagaca aacagtaata aaaattttac ttgaacaaga
    35701 tgattcaaat ttggaaaata ttgcttcttc actgataaaa tcttcaaatt ctcaaaaatg
    35761 ccttggaggt cttgaaattg taaacttatt aaaagacaat actgctagac aagaactata
    35821 taataagctt attttactta tagaggatat tgataaatct aaaaagaata catctcaagt
    35881 tcaaatacta attgataatt tgttaggtaa agcaaaaaat gattactgca aagaaaatgg
    35941 ttttggaata tataaccctg aaaacaaagt tcaaattcca gaacaatttg attttaaaga
    36001 tgattctaat agctcatcaa agcttaataa aattatctca aatataagtt tatctactcg
    36061 tgaggattct gtttctgtag caacaaaaaa agaagcaaaa aaaattctcg atacggatat
    36121 aaataaaata ataaaagttt atgaaaaatt tgatgaactt attactgaaa atgcagatta
    36181 tgaatatgaa gttgaaagat ggtcaggtaa tgtagacaaa gtacttttag gttattctac
    36241 ttataacttg actcctatta aatataaagt ttctaatgat actcttgata attatccatt
    36301 agcagagctt tggagagaaa ctagtaaaaa acttgactta gattacaaat taatacttga
    36361 tatcttattt tatagtataa gtacatgtgg atataatgaa acagaaaaaa gttggttttc
    36421 atctatatat tcaaatgtcc ttgactctaa aaaacaaaat aaaatatata caaaacttga
    36481 aaaacttaaa tttaatggac ttacaagaaa acttttaaga gttttactaa atgagtttga
    36541 ccataaagaa atatttaact attgtttaga aatatactat aaacttagaa acttattgac
    36601 tatagaacaa tgtaaaaaac aaagagttga atttactaaa aactattaca gacaaaatga
    36661 atactgccct gctttaaatg cccctatttt aaactattgg cttgataaag cacattcgtt
    36721 tatttatgat gatatttctt ttactaagtt tttctacact acgttttcaa attatcagtt
    36781 gctagaatat aagtttcctt tctatactag cataaatgtg tttgctcgtg cacatgaatt
    36841 aggattaatg actgaagagc aagttaatag agaaatgata agtggataca acgcatcaaa
    36901 tataataaga acattgacaa atcctagatg ggctggcgac acattagaaa agtacccttg
    36961 gcttaaagat aatttaaaaa ctgttacaaa ccgaattata gaaattgaat cacgtagagg
    37021 tgatatgcca acagaagtgt ctaatctagc taataatata caatactttg aaggtataaa
    37081 ttattttgta aatattttgg tcgctcttgg taaagaaact ttccagagag gatattcata
    37141 tggtagcaat tattcaaaaa aagatgtttt aagttctcta cttaaaaatt gctatcctac
    37201 taaagaagat gattcaaaaa aattaaaaag tttacttaaa aataccgaca ttactgagtt
    37261 aagattgata gaatctgcta tgtatgcccc tcaatgggta aacataattg aaaaatattt
    37321 aaactggaag ggtctgaaaa gtacaatttg gtacttccat gcacatataa atgaaggctt
    37381 ctctgcacaa aaagaatcag aggttgctct attctcccct atttcaccac gtagtttcat
    37441 tgatggtgca tttgatgtag attggttttt agattcatat aaaactattg gggaagaaag
    37501 attcaatata ctttacaagt cagctaaata tataactagt ggtggtaact ctcatagacg
    37561 tgcacaactc tatgctgatg ctacacttgg taagcttgat aaagacatgt tgatgaaaga
    37621 aattgaaaca aatagaaatc aagataaatt gagaagtttc tctttacttc ctatgaaaaa
    37681 aggagaccta aaagaagcaa ctttccgtta tgaatttatt caaaagtttg ctaaagaaag
    37741 caagcaattt ggtgcacaac gtcgtgaaag tgaatcaaaa gcttgtacta tagcgctaga
    37801 aaatctagct agaagtgctg gatttggaga tgtaaatcgt atgatgtggg ctcttgagac
    37861 tgaaaaacta aatgaagttg ctcatctatt taaaccaaaa gatattgatg gtacttcaat
    37921 ttggatagat gttgatgaaa acggaaaagc atctactaaa gttcaaaaag gcaacaagtc
    37981 tttaaagagt ataccaaaag ctattgctaa acatccatat gtacttgaac ttaaatctgt
    38041 ccaaaaagat ttaaagagtc agtattctcg tgcaaaacag agtttagaac aagctatgaa
    38101 aaatgaaata gtatttacag ttaaagaaat tgccaatatc tataaaaatc cagttatctg
    38161 ccctttgatt aaaaatctag tatgggtatg tgatgataat attggatatg tttataatga
    38221 taagtctaag ttctttattt gcaatataga aggtgaaact tataagttga cggcaaaaaa
    38281 taaattaaaa cttgcacatc cagttcattt gtttgaatct ggtaagtgga gtgagttcca
    38341 acatgattta tttagtaagc aaattgttca accatttaag caagtattcc gtgagtatta
    38401 tagaataaac agtgatgaat tatctgaaaa aactatatct cgcagatatg ctggtcacca
    38461 aattcagcca aagaaaactg tagcacttct tagaaatcag ctttggactg tcgattatga
    38521 agagggatta cagaaagtat tttataaaga aaatatagtg gcaaagatgt ttgcacttgc
    38581 agattggttt tcaccagcag atatagagcc tcctactatt gaaacagtag aattttttga
    38641 tagaaaaact tataaaagtt tagaattagc ttctatacct ccaattctat tctcagaagt
    38701 tatgcgtgat atagaccttg ttgtaagtgt cgctcatgct ggtggtgttg accctgaaac
    38761 tagccattct actgtagaga tgcgtatagc aattgctaaa gaacttttat tattattaaa
    38821 aattaacaat gtcaattttg aaggctctca tgctcttata gcaggtaatt taggtgagta
    38881 ttctgtgcat atgggttctg gtattgtaca taaaaaaggg atgggtgctt tgaatatact
    38941 tcctatacat tctcaaagta gaggtaagat attccttcca ttcgctgatg aagaccctaa
    39001 aactgctgag attatgtcta agatactatt acttgctgaa gatagtaaga ttaaagaccc
    39061 tagtatctta agtaatttat aagtataaaa actatctcta aaatatattg gactttctta
    39121 aaaaaattag aaagtccaat atatactata ctgtaattta tatagattaa atcataatta
    39181 caaataattt ttatataaac ttctcttata cattatcttt acggtactta ttatatcaca
    39241 caaaaagtat ttttcttcta tcttcactag aatcttttaa ccctataaaa tctatataaa
    39301 aaatcttttt ctagagattt gtttaatatg gcattttctt gaaaatttat aaaccttatc
    39361 tctaatgaag atttatttat aggtataacc ttatgtataa atcttagatt tactatgtat
    39421 tgtctatggg tcataaagaa attaggaggt aggcgttttt ttaaatcatc aaagttctca
    39481 taaaacttta ttatatcttc atctttagtg tgtagattaa ttgctcttga atttttctca
    39541 aacataacta tatcatcaaa attaatcata tgtatctgct tccttatttt atatacaaaa
    39601 agggtgtctt ctataaaatt attattagca atcttatggg agttaatatg gtctattgct
    39661 atgttaattg aatcaagtat tttttctttt ttaaatggtt taactacaaa atctatagga
    39721 tgcactttaa agctttcaag actataatca gcgaaacccg tcacaaatac tatatgtata
    39781 tccttatcta tagaaagaat ttcttcagca gaatcaatcc catttttata tggcatatca
    39841 atgtcaataa tcaataaatc tattttctca ttttttataa attcaattgc ctctatacca
    39901 tccttaactt ttttaacata atctacatat ccagactctt tagctatatt tgctatatca
    39961 tctcttacaa tcttatcatc atcacaaatc aaaactttta tcatagactt ttctcctcct
    40021 aactaataat attttgggat taagattaca aattcagtta aaaaatcatc actatttaca
    40081 agtatactat aatcatactt atctaatata tttttaacta aatgtagccc atatccccta
    40141 tcttgtcctt ctttagtact aaatccattc caaaatatac tttcaacatt atgtatttta
    40201 ggaccattat tttttatagc tataatatac tgaaattcat cttcatatgc atgtaatctt
    40261 atatacttct tttctttttt tatagtagac aaagactcta ttgcattatc tattatgttt
    40321 aatagtactg aactcatatc attaggttca atctctaaat tatccataaa atcttgaatg
    40381 tagacatcaa aagatatatc cttttcaaga cattcctcgt attttaatga agctatagca
    40441 tctaaataag atacttttcc ataccttgaa ttttttgatt taaagctatt tgatatattc
    40501 attatatatt ctttggcatc ttcatctagc ccagtattta atagagaata cactacttgc
    40561 aaatgtttca aatagtcatg tttttgactt cttaatttga taattatatt atccttatga
    40621 tttattttac tatctagttt ttgtaattta tattcctgtt cattattatt atttatcaat
    40681 cttataactt taaagcctgt ataaaaactt aaaataatta aaaccaaaaa aagtataata
    40741 tttaatactc cttcaagtaa aaaactatat cctaacctta attgtatata tttagtgccc
    40801 tccataaata aaatcaatgc aaaacacgat ataaaaaatg ttaatatgcc tctttttaat
    40861 atgtctaatt ctttgtaaaa tttatactta ttcattataa gattgctaaa tataaacaaa
    40921 gttagtatta ctataggaaa tacaaaattg ttatccatga ttcccctccc ctctacaatt
    40981 tatataggga ttatatcatt ttaaaaaaat tatgtaaaaa gttaaaattt acatatatat
    41041 taattaaact tgtaaaaata cagatgaatt tgtacaatta actacttaaa atttgaaaat
    41101 acttactttg ctatatattt tagataaata tataattgat ttagttaaga aaggaagtgg
    41161 taaatatgaa agataatttg aaaatagtac taaggtatat aaaaagttat aaagctaggt
    41221 ctttagcaat tgttgtgagt ataattcttg ctacatcact cgttgttggt attggtactc
    41281 tctcaagaag tgctcagcaa gcagatgtag atagattgaa aagagagctt ggaactgacc
    41341 atgtatactt taaaaatata aagaaaaatc aattaaagtc cataaaatct agcaaagata
    41401 ttaaaaatct gggtataaca tcttactatg cgtctacaga tgttaatgaa aaattaccta
    41461 taaacatact atatacaaat aaaaattatt tgactagtca ttctaaactt ataaaaggtc
    41521 gatttccaaa agctagcaat gaggtggtag tcgagaaatg gattttaaat agtatgggct
    41581 taaaaccaga gataaatcaa aaccttactt ttaaattata tcaaaaagaa aatccagaaa
    41641 cttttaaagt tgttggaatc cttgaagata gatttataga gaaaaaaaag ggacaatgtg
    41701 aaattttttc taatctcaat gaatcagaac tgaatgattt tacaacttat attgaattta
    41761 atgaaggcag tgatataaat acaaacatag acaatataat aaaaaatgct atgttagatg
    41821 agaaaagtat aggaagaaac tcaatgctta tagaatctac tatgaaaaac ggtactttag
    41881 ataattcaag taaatacgtt gcaattgcta tgagtctatt tgctggtatt gtaatatata
    41941 gtatctatgt tatatcaata taccaaagag tacaggaata tggcgtctta agagctattg
    42001 gttccaccaa ctttaggatt ttcaaactta tgctttatga acttttcata cttgctctaa
    42061 tagcaatgcc tataggtata tgtataggta tgggaggtgc acaaatattt aataggtctg
    42121 taggaaatat tcaatttgaa ggaaatataa atgttacacc ttttgttatt ccagataaaa
    42181 taattctctt atcaattgca tgtacaatac taataatact aattataagt ttctttacat
    42241 acttaaaaat aagaagaatt tctcctattg atgctatcag aaaaactttt ggagctgata
    42301 aaaatgtaac caaagttaat tatttaatat caaaattaac tttaaatatg tcagtaacaa
    42361 aatctatatc tgcgaaaaac atctttagaa ataaaaaggg gttcattata attgtattat
    42421 ctatgagtat aggaggtata atcgtcataa aagacaatta taaatattct tttttagatg
    42481 tgcaaaacaa atctactcaa gaacaaacat atatgaatgc agattttatt ctatcaaatg
    42541 tttatctcaa tgaaattggt aacaatactt cttttaaaga tataaaaggg tttaatgata
    42601 atcagataga taaaataaaa aatatagatg gaattgacaa agtcaaaact gctagtatct
    42661 taaacacaag aatagaggta aataaaataa atagattaga ttactacgaa gctataaatt
    42721 caactcctta ttataagcta aatcctctgt tcataaaaaa taagactact ggcaaatata
    42781 cactaaagca aaagctaaaa ggttataatg atgagatgat aaagtcatta gaaaaatact
    42841 tagtaagtgg aaatataaac ttgaaaaaaa tgaaaaaaga aaatttagct attgtatatg
    42901 taccagaaat ttctaaaaca cagaaataca caaagacttt tactcctggt gaaggaacac
    42961 cagctgtaga tataaaagta ggtgatacta taaaagtcaa atatccaaag ggtgggatgg
    43021 atacaggtct ttatgaaagt ctaaaagata attatgaata cttagaatat gaatttaaag
    43081 ttggagctat tataagttat ccttttgcag ataatggtat gtactctgga gatgatggtg
    43141 tagatgtaat aacgagtagc gaatacctaa aaaaattaac tggtgtagat aagtataact
    43201 tagtttatgc agaccttaat gaaaatgcaa acaagaaaaa aataaataac cttttaggta
    43261 aaattggaag tgaagttcct ggaactacaa cagtagatat gatggtagaa aaagaaaatt
    43321 ctgataagat gacatctaga actatgattt atagttatgg tatagtagca ataatgttca
    43381 taatcagtgt acttaacata ataaacaaca taagttataa cttaacttca agaactagtg
    43441 aatttggaat gttaagagct attggtatct ctgagagagg ctttaaaaat atgatacttt
    43501 atgaaggaat attatatggt gtactctcaa gtataattac tatcgtgtca ggaattataa
    43561 tacaatttaa aatgtattat atgcagggct ttgtatcata tggattggga ttttcaatag
    43621 attacaaaat atatatacta gttgttgtag caaatataat tgtaggtatt ctagctacat
    43681 atattccatc aagaaagata aataaaatta gtatagttga agctataaac attacagaat
    43741 aggaggaata attatgccta tattggaaac tattaactta ggtaagattt atggaaaaaa
    43801 ggaaacatct gtacatgcac taaagaatgc aaatttaaaa ataaataaag gcgaatttgt
    43861 tgctataatt ggaccaagtg gaagtgggaa aagtacattt ctacatttag taggtggtct
    43921 tgaaagacca agtaatggta ctataaaggt agatggtaaa gatatatgtt gtctttcaga
    43981 taaagaatta gcaagatata gaagacaaaa ggtaggattt gtctttcaac agtataactt
    44041 aattcctgta ttaaatgtaa aggaaaatat agaattacca ctaaagttag acaataaaaa
    44101 aatagataaa gaatatattg atgaccttat aaatttattg ggtcttaatg aaaggaaaaa
    44161 tcatcttccc aaccaattat ctggtggtca acagcaaaga gttgctattg cacgtgcttt
    44221 atctgcaaaa ccaagtataa tcctagcaga tgaaccaaca ggaaatttgg acagtaaaac
    44281 tacagaagaa gtcatggatt tactaaaaag ttctataaaa aaatataacc aaacacttat
    44341 aataataaca cataatgaaa atattgctag aaaagcagat agaattatat ctataataga
    44401 tggagagctt aaattaacac tctaaaacta tttatagaaa agaggattta aatgttattg
    44461 attttaggta atttaaattt aaacttggat tttgactaca gaataataag agaagaaaat
    44521 gaagatgtag atatatttat agatattaat tatcgtagct tagatataga tactgatggt
    44581 tctaacttat ttaattctag aatacaattt ccatttgtaa gagcattgat tctaaggcta
    44641 aataagaaca atcaatgtat gacaattcat ttgttaagag atatagattt attctctgct
    44701 tttgccaact ttgaagtgga ttatactgac tctataataa atataaaaaa tcaaaatgag
    44761 aaagtaattt taaataaatc tatcaaaaaa tagtaagggg gccttaatag gccccaattt
    44821 ttttcttttc taaacttatt atatcatgat aaataaatta gtcaatagaa ttttctgaat
    44881 atttttataa ttttttcata aagtttttta tatattatgc tttaaaatta tatgtaataa
    44941 aaaaattttc cgactaattt taaagttaat tgattaaata cacatattcg aaattaccat
    45001 taaattactg actttttatc atttccattt agaatttaaa ttataatcta ttatttatag
    45061 ttacttctac gtgtctctaa taaaactcta tttatattca aatctaataa tttatataca
    45121 aacccaatag aacctatgtt gcacaataga tattatttac cataataaac ttttagatat
    45181 atctctttta attcactcat caatgggtat ctaggattag cacctgtaca ttggtcatca
    45241 aaagcttgtt caaccatagc atccaatctt tctaagaatt tagattcttc tactccagcc
    45301 tcttttatag tcttaggaag acctactttt gcctttagtt catctattgc ttttataaga
    45361 ttatctactt tttcttggtc tgtacttcct ttaatacctg caaaagaagc aaattcagca
    45421 tatctttgta tgcaatcagg atatctgtat tgtgagaatg cacccatctt atttggagct
    45481 tctgcacaat tgaacttgat tacttcattt attaataatg catttgcaac accgtgttga
    45541 acatggtgga atgcacctaa tttatgtgct aaagagtgac atattcctaa gaaggcattt
    45601 gcaaaagaca ttcctgccat agtagatgcc attgccattt tttctcttgc ttctttatca
    45661 ttctttccat ttttatatgc acgaggtaaa tattcaaata ttattttacc tgcttgtagt
    45721 gctagaccgt cagctggttc agttcttaac atagatacat atgcttctaa tgcatgtgtt
    45781 aaagcatcaa cacctgatgc tgctgttaat cttggtggca tctccatcat catatcagca
    45841 tcaattatag ccatgtttgg cattaattca taatctgcta atgggtactt tacacctgaa
    45901 tcttggtcag ttataactgc aaatggagtt acttctgaac cagttcctgc tgaagttggg
    45961 atagcagcaa aatacgcttt ttcacccatc ttaggaaata catatactct ttttcttata
    46021 tccataaatc tcatagctaa gtcttggaaa tctacttctg gatgctcata cattacccac
    46081 attatcttac cagcatccat tgcacttcct ccacctacag ctattattaa atctggttgg
    46141 aaatcagcca tagctttagc tccttctctt gcacaagcta atgttgggtc tggagctaca
    46201 tcaaagaatg tagtatgctt aattcccatc tcatctaata aatcagttaa tttcttagta
    46261 tatccattat tatataggaa agaatctgtt actataaatg ctttcttttt atccataaca
    46321 tccttaaatt ctcttgctgc tacacctaaa catccttttt tgaaataaac cttttctggt
    46381 gctctgaacc aaagcatatt ctctctcctt tcagctactg tcttgatatt aagcaaatgt
    46441 tttactccaa cgttttcaga tactgagttt ccaccccaag aaccacaacc aagagtaaga
    46501 gacggtgcca atttaaagtt atataaatca cctataccac cttgtgatga tggagtatta
    46561 actaatactc tacaagtctt catagcattt acaaactttt ctactctctc tggatgattt
    46621 atagagtctg catataatga agatgtatga ccatagcctc catctgcaac taatttttct
    46681 gctttagcaa ctgcatcttc aaaactttta gacttgtaca ttgcaagtac aggagaaagt
    46741 ttttcatgtg caaaaggttc atttaattca acagattcta cttcaccaat tattattcta
    46801 gctgtttttg gaacttctac atccgccatt ttggctatta catgtgctgg ttgtccaact
    46861 attctggcat ttaatgaacc atcaattatt actacttttc ctactttttc agtttcttct
    46921 ttatttagga aatgtgctcc acgatattta aattcttttt taacttcttc atatattttt
    46981 tctggtacta ttacagcttg ctcggaagca catatcatac cattatcgaa tgattttgat
    47041 actaagattg aacttacagc catttttata tctgcactct catctattat tgcaggtaca
    47101 tttccaggcc caactccgac agctggttta cctgaagagt atgcagattt aaccattcca
    47161 ggtccaccag tagctaatat aaggtctgcc tctgccatga caacattagt taattcaatc
    47221 gaaggaacat ctacccaacc tataagtcct tttggtgctc ctgccttaac tgctgcatca
    47281 tgtacaactc tagctgcttc tatagtacag tttttagctc ttggatgagg agagaaaatt
    47341 ataccatttc tagtttttag tgctattagg gatttgaata ttgcagttga tgtaggatta
    47401 gttgttggta taactgctga taaaacacct actggctcag caattcttgt aaaaccaaat
    47461 gcttcatctt tttctatgac accacaagtt ttagtatctt tataagcatt atagatatat
    47521 tctgaggcaa aatggttttt tataacctta tcttcaacaa tacccatacc agtctcttcc
    47581 actgccattt ttgctagagg tattctttgt tgattagctg cagttgaagc agctaagaaa
    47641 atcttatcta cctgttcttg cgtaaatgtt gcaaattctt tttgtgccaa tctaatttct
    47701 tctaatctca ttcttaatgt ttcaacactg ttgacaattt caggactaca tacttcaaca
    47761 tttgattttt ctactacctt ttcttttttc tccatactaa aaacctccct aaaataatta
    47821 tgcatctcta atttttataa atcttaaatg catcatctat atttttaact tatacttaaa
    47881 ataattttat agatttcatc tctatacctt agattttatt tattttactc tcttaggtca
    47941 agaagttttt ttctgaatat tttgtcaatt tattttttaa caaatatatt atttttttta
    48001 cttttactaa aattttttat ctaaatgaga tatatttcat ttgaataatt tacttcgact
    48061 aaataaaata ctaaaatgat aatttatatc ttt
//
LOCUS       DAMKNB010000025        46146 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.026, whole genome shotgun sequence.
ACCESSION   DAMKNB010000025 DAMKNB010000000
VERSION     DAMKNB010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 46146)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 46146)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..46146
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.026"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            190..3738
                     /locus_tag="PC494_001569"
     CDS             190..3738
                     /locus_tag="PC494_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HDF3912073.1"
                     /translation="MMNRLKPRILGISILFIIIIILTCGAVFKFKFKLDNKLKETTHT
                     YLSEFTEHNIINLKTRLSGQFDMLESIANFIGNLNNINDEMVIDLMDSDVKRSSLIRM
                     TISTLDGECYSNDGITHNVQDRDYFKKAKNGEKNISEPLKSIVNNKEIIVLSTPVYKS
                     GKIVGVLSGIYDSKKLNELLGLSAFDEKADVFVAKKNGDIVAQKTNKNRKTLSCIFQL
                     FDKDNCDEDDCLKTIKENMKNDKSGYFNYNLDNEKFMLNYQPLGVNDWYVFSVVPNKI
                     VSIQSENISYDVYIFALEILLVILIFIIYIACIINNNTKIIINEKEKFKVLTDNILGG
                     VKTCLKDEYMTMTYVSQGFLELTGYSCEDLNKIFKNRFKDMIYKDDLDKFNCIILNQL
                     EKQDKIEVEYRIVRKDGSIIWILERSKSINDNKGSECIQGVLTDITELKKIQEELDSK
                     RFEIQAINDSIVGGIVITEINDDFDSIYLNEGYLNMIGYTRKQLEDELNNKLIKLIFK
                     DDRTELINSINKQLKLSDTFASEQRVEKRDGTIIWILLKGRKMIYDNGKSVLCCVIVD
                     ITSAKLLEQELKKSEERHEIILKQTQNIIIEWDIEKDKMNISPNWYNKFKYDPITENA
                     TKNIIKSVDIYHDDMDKFISLIKLTSQGSEYEECEIRLRTRDTIYAWFSIKATTLFDN
                     NGKPYKVVGSLTDIDESKREAEKLKERAEKDPLTDLYNKKASQSLIEEYITLDKKRKG
                     ALMIIDIDDFKGINDNLGHLYGDAVLSEIANDLINLFRATDIVGRIGGDEFIVFIKDI
                     SETRDIINKAEELVKTFERSFLGKGRNYKISLSVGIAKFPQDGMDYMTLFRNADIALY
                     SAKGKGKNCYTLYDKKFDKVQYITNTRNAGDSDNVEMSFKEHITNYIFDILYESSDIE
                     VAVNLILSIVGKHFNVSRMYIFENSDDNRVCKNTFEWCNEGVTSEINNLKNICYKDLG
                     NYLLNFNADGLFYCNDIENLGSDVKKVLKPQGIRSILQCKILEGNEFRGFIGFDECSY
                     NRMWTNDEVNTLTFISKTLSMFLLKMRIQSKLEESLTIQKSVMDNMDIWAYVVDRNTY
                     ELLFINKKMLESAPNTHVGDLCYKAIWNNQDKPCKKCPMIYLKDGDDTYKSFMHNKKF
                     EVQANITTTTLKWFDGKDACLIFGSEITSIEAEENT"
     gene            3923..5857
                     /locus_tag="PC494_001570"
     CDS             3923..5857
                     /locus_tag="PC494_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YgiQ family radical SAM protein"
                     /protein_id="HDF3912074.1"
                     /translation="MENKFLPISKQDMIDRGWEELDFVLVTGDAYVDHHSFGTAIISR
                     VLESAGYKVGIIAQPDWRTTDDFMKLGKPRLAFLVNAGNMDSMVNHYSVSKKHREKDM
                     YSPGGKMGYRPDRATIVYCNKIREAYSDVAIVIGGIEASLRRFAHYDYWSDKVRKSML
                     IDSGADLLVYGMSEKQIVEVANALNDGYDPKYIRHIDGTCYISDTLEEIYDKYILIPS
                     YKEICEDKMKYVEAFKIQYDEQDPFRGNIIVQPHGSKYLVQNKPEKPLSREELDEVYG
                     LPYQKTYHPVYEKFGGIPAIEEVKFSIVSSRGCFGSCSFCAITFHQGRAVQSRSEKSI
                     IDEAIGITNLDDFKGYIHDVGGPTANFRRPACKKQITKGACKNRQCLSPSPCKNLDAD
                     HSEYLHLLRAVRKLPKIKKVFVRSGIRYDYVMADKNNKFLRELIEHHVSGQLKVAPEH
                     ISEEVLKYMQKPAGKTYDKFRQKFFAINEELGKKQYLIPYLMSSHPGSTLNSAIELAE
                     YLRDTHYQPEQVQDFYPTPGTLSTTMFYTGIDPLTMKPVYVPKSKRDKAMQRALLQYR
                     APRNYDLVYSALVEAGREDLIGFGHRCLIKPKNEKPYFNRNNSKKNVSKGTNKNKKTN
                     TNNRSNKNQQKSSTKKKKKH"
     gene            5963..6958
                     /locus_tag="PC494_001571"
     CDS             5963..6958
                     /locus_tag="PC494_001571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDF3912075.1"
                     /translation="MKKYISIILLVVLTMVVLVGCSPGKDNPKNKELSVVKQVKVAVP
                     DGLPAVAIAKLANENPEIKEGYETVYSIEKTPEAISTRVMKKDADIAIVPSNMAAIAY
                     NKTSSYNIVGTVGMGSLYLVSTENIKDYSDLVGKEVGCTGKGLTPDITIKSLLLQKDI
                     NYSDIKFNYVNSASELVPLLATGKVKTGIVPEPALSALMSKNPDIKIIKSLNDSWKEV
                     SGSKDGYPQSTLIVKSEFLRDNKDFVDSFVGQLSNSIDWANKNPEELGAYSEKIKIST
                     ESKIIGKSLERANLKYIPVKDMIKDYKNYYEKLANFDDKTLGGKVPDEAIYFVEK"
     gene            6986..7714
                     /locus_tag="PC494_001572"
     CDS             6986..7714
                     /locus_tag="PC494_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HDF3912076.1"
                     /translation="MEVTLSCVILLFLWQIIALKIDNDIFLPTVGQVFNSIKEIMLNS
                     SFYIDILYSMGRCFFSFLLAMIFAIILSIVSYLNRFFRNLLKPINALTRSIPTMILVV
                     LALIWFEKDSTPFIVGFTIVFPILYDNVLGAILNIDKNLLEMANVYKIRFIDKVLKIY
                     LPAIKFQIISILVSTFSLSLKVAIAGEVYSQPTYGIGTMIQTEKINFNTSGIFAWIII
                     VLLISAILQIAQKFLARRAFLWKR"
     gene            7702..8400
                     /locus_tag="PC494_001573"
     CDS             7702..8400
                     /locus_tag="PC494_001573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF3912077.1"
                     /translation="MEKIKLSIENINKRYDSRIIFRDFNIDFYVNEVNCILGKSGCGK
                     TTLLNIISGIIKNDTNNLNIKENLNRVGNKLEASYIFQDDRLIDWLTVEENIKIVVNK
                     YYNKTQLNKICDEYLELVGISDYKKFYPQMLSGGIRQRVNIARAFIYPSKNIIMDEPF
                     KSIDAKNTQLIMDNFRNILRKEKRTVLFVTHNIEEALFLADRIFILGDSPIRIKKILK
                     NSKELEKNEVLKLI"
     gene            8523..8996
                     /gene="ybaK"
                     /locus_tag="PC494_001574"
     CDS             8523..8996
                     /gene="ybaK"
                     /locus_tag="PC494_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-tRNA(Pro) deacylase"
                     /protein_id="HDF3912078.1"
                     /translation="MVKTNAMRILDSNKIDYKVMSYEVKSEHVDGVEVAHDIGRDVNE
                     VYKTLVTQGVSKNIYVYVIPVHENLDLKKAAKVAKEKSVEMIHVKDINKLTGYIRGGC
                     SPIGMKKLYKTFVNESAKNLDTIIVSAGKIGYQIELSPFDLQRLIKVEFVDVIKK"
     gene            9193..10032
                     /locus_tag="PC494_001575"
     CDS             9193..10032
                     /locus_tag="PC494_001575"
                     /EC_number="4.2.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fumarate hydratase"
                     /protein_id="HDF3912079.1"
                     /translation="MRKIKSEQIVEQVKKLCIEASLYLGEDVLSCIKEKAKSEKSEVG
                     KNILNILVENAEIAKEKNIPICQDTGMAVFFVEIGQEVLIEGDTLTDAINEGVRQGYE
                     EGYLRKSVVSPINRVNTKDNTPAVIHYDMVKGDKIKIEFAAKGFGSENMSKMKMLKPS
                     DGLEGIKKFIIDTVSEAGPNPCPPMVIGVGIGGTVDKCAQIAKKALFRELGEFNKDEN
                     IAKLESELLTAINKLGIGPQGLGGTTTALGLNIETFPTHIAGLPVVVNINCHASRHKK
                     VVI"
     gene            10045..10593
                     /locus_tag="PC494_001576"
     CDS             10045..10593
                     /locus_tag="PC494_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S-containing hydro-lyase"
                     /protein_id="HDF3912080.1"
                     /translation="MIKITTPVNEIDIAKLNCGDTISLSGILYTARDAAHKRLIDCIN
                     KGEELPFDVYGQGIYYVGPTPTKPGEVIGAAGPTTSYRMDDLTIPLLERGLRLMIGKG
                     KRSDEVIEGMQKYGAVYLAAIGGAGAYISNSIKSCEIIAYEDLGAEAIRKIVVEDLKL
                     TVAIDSYGNNIYEQGRAIYECK"
     gene            10659..11840
                     /locus_tag="PC494_001577"
     CDS             10659..11840
                     /locus_tag="PC494_001577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent malic enzyme"
                     /protein_id="HDF3912081.1"
                     /translation="MSKDYAKLALEMHEINKGKVSVESKVEVKTKDDLSTAYTPGVAE
                     PCLKIHENQDDVYRYTSKGNLVAVVSDGSAVLGLGNIGAEASIPVMEGKAILFKQFAD
                     VDAFPICLKTNDVDEIVKSVELMEPVFGGINLEDISSPRCFEIEERLKKSLSIPVFHD
                     DQHGTAIIVAAAIINSIKLIENKKIEDLEIVINGAGAAGIAIAKILLNMNVKNIILCD
                     RSGALEASIENLNYVQKEMLKVTNIRNEKGPLKDIIKGKDVFIGVSGPGAVTKEMVES
                     MSEKPIILAMANPTPEIMPEEAKLGGAFIMGTGRSDFPNQVNNVLAFPGIFRGALDVK
                     AKEINEEMKIAAAYAIANTISDEEICPEYILPDVFNKNVVKNVAKAVKEAAIKTKVNR
                     I"
     gene            12135..12521
                     /locus_tag="PC494_001578"
     CDS             12135..12521
                     /locus_tag="PC494_001578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009248914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDF3912082.1"
                     /translation="MEYKVNDQELNASMFIPFVNRIWPGDYDMDKTQTALSKTLNITA
                     YDDKVLVGCLRVLSDGYYFGTITELLVLPEYQKQGIGSKLFQLAKENTPTMLYFGAQP
                     GVEEFYEKNGCQRSLQSYIIKKKDSY"
     gene            12671..12934
                     /locus_tag="PC494_001579"
     CDS             12671..12934
                     /locus_tag="PC494_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HDF3912083.1"
                     /translation="MEETKFCQCCAMPMGQTDELYGTNKDGSKSTDYCSYCFKDGEFT
                     ADISMEEMIEVCIPHMLQSNKDMTEDEARTMMNNFFPTLKRWK"
     gene            complement(13063..13905)
                     /locus_tag="PC494_001580"
     CDS             complement(13063..13905)
                     /locus_tag="PC494_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HDF3912084.1"
                     /translation="MINIGDFNKLTVKRKTEFGYFLDGQTNNTKDDILLHNRLIGKNE
                     INIGDEVNAFIFKDSDDRTAATLIPPLAKVGDVAHLKVVDNTDIGTFIDMGLPKDILV
                     PFKAKTYPLFRDEKYLFYIYLDKSKRIAATTDIDSYLLTDHTYNVGDIVTGVVYGFQT
                     NNSAMICVDNKYAGVILHNEYFTELKTGDVLENLHVIKIYEDGKLGLSPRGNRKDELD
                     TLENKILSYLEGSDGYMRFNDKSDPKDISILFNSSKKNFKRALGVLMKKGLIYQDEEG
                     TYLK"
     gene            14200..14934
                     /locus_tag="PC494_001581"
     CDS             14200..14934
                     /locus_tag="PC494_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDF3912085.1"
                     /translation="MKIVNKSSNIPLHTQLSSIIREMIETGELKEGDAIMPERELCNI
                     QNVSRMTVNKTIVGLVTEGLLYRVQGKGTFVAKQKKKYQFSNVKGFTDVMKEKGVNIK
                     TDILSFEMELPDDLVKRKLGISDNTTNIYKIVRLRYTDGEPFGLEIVYLSEEMCKGLT
                     KGILDNSSLYRVLNEKYGYKIQKAEQVMEPVILSDEESKLLETDEGALALKLHRNSYN
                     REGSPIEYTISIFRTDKYQYEIVLSE"
     gene            14944..16077
                     /gene="nagA"
                     /locus_tag="PC494_001582"
     CDS             14944..16077
                     /gene="nagA"
                     /locus_tag="PC494_001582"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HDF3912086.1"
                     /translation="MKCLINGKIILKNQILENKVLVFDEKIIDIADSVPKDCEVIDAD
                     GKYISPGLIDIHIHGNMGKDTMDSTDESIETISKSIMRHGVTSFLPTTMTMDKEHVYD
                     ALEVIKKAQNRKLEGAQVLGAHLEGPFINENYKGAQNEKFIINSKYEFIKEYKDVIKV
                     ITYAPEKDIDFDFTREIKRCTDIVLSIGHSNANYDQAKEAINLGVTNVTHMFNAMTGL
                     NHRDPGVVGAALTTNVYSELIADTIHINKDLFQFILNNKGKERLILITDSIEAGGLED
                     GNYSLGGQKVIVKGNEARLENGALAGSVLSLNKMVFNFLDNTNLKVNEAINLASLNPA
                     TSLGINDKKGSLEIGKDADIAVFDENLDCKMTLCLGDVVYKNI"
     gene            16176..16925
                     /gene="nagB"
                     /locus_tag="PC494_001583"
     CDS             16176..16925
                     /gene="nagB"
                     /locus_tag="PC494_001583"
                     /EC_number="3.5.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012425552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HDF3912087.1"
                     /translation="MRVLVCKDYDGMSKKAAEMIAAQIVLKPNSILGLATGSTPVGMY
                     RDLVKKYNDNIVDFSDVMSFNLDEYYKLPISNDQSYDYFMKENLFNHVNIKPENTHLP
                     NGMADDIEKECMNYEASIDAAGGIDVQVLGIGRNAHIGFNEPDTKFAKRTHVVELTES
                     TIEANARFFKSREDVPKKAVSMGIGSILKSKKILLLASGEEKADAVYNTVYGDITPEV
                     PGSILQLHKDTIVIVDEAAASKLNPKDYKLV"
     gene            17100..17372
                     /locus_tag="PC494_001584"
     CDS             17100..17372
                     /locus_tag="PC494_001584"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3912088.1"
                     /translation="MLKIIMFSGILSSIIKLPIIGILPTGNIKKNTGISDSKKDGKQR
                     RSNLGISIYQLPSFLYSLINNSVPSNKPIPPEEIKLIKMYLLKSCI"
     gene            18032..18736
                     /locus_tag="PC494_001585"
     CDS             18032..18736
                     /locus_tag="PC494_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF3912089.1"
                     /translation="MSKLIYIADDEDNIRNLVKTFLKNEGHDVMDFKTGDELLEQFNI
                     KECDLVILDIMMPGSSGFEVCTKLREKSTVPIIMLTARDTDIDYITGITLGSDDYFTK
                     PFSPMSLVMRVKSIFRRIEFEKKQNYDKYSNSIDMELKFGDVIINKKNKIVTSKNVNI
                     DLTPNEYNLLTYLFENIDRAVSRDELLNKIWGYDIEVETRAADDTVKRLRKKILNTNI
                     LIETVWGFGFRLKEKS"
     gene            18738..20225
                     /locus_tag="PC494_001586"
     CDS             18738..20225
                     /locus_tag="PC494_001586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF3912090.1"
                     /translation="MKNGNDKNRIGKIKSKFKLKFSKKNISIKTRILLSILCLIIIVF
                     MIILVSFNVFLDTYIKTTANEELTKSTEIVEHMDSNFRPIKPPQDDGKLPPKVLSNFM
                     RNVQDKVRMAETQSDADAMVVDSKYNLIFPTREDDFLKNVDEMELIRECIQNEKLDLN
                     SDENTRISTRNKDYYISTVKITSIYGEQDKYLILFIDISKTLNLAQKINIVLISVMCF
                     AGILAIFTAVILSEKIAKPIKELCEFAKKMGQGDFKRTYFDFSDKELVELSTVMNKSA
                     EYLDKYDNEQKIFFQNASHELRTPLMSIKGYAEAIKYNVIDSKHASDIILEESDRLSD
                     MVEDLLYISKIDNITKDFELVECDLREVLSNCGARQNVRAINKGIKFIYEFDEEMVLF
                     ECDEKNISKAFMNLIENALRYAKSEIKIVCKYNQKNIVVIIEDDGIGIKKEDLPHVFE
                     RFYKGVGGNHGIGLSIVKSIVNKHGGRIYVENGKKGAKFTILFKL"
     gene            20430..22043
                     /locus_tag="PC494_001587"
     CDS             20430..22043
                     /locus_tag="PC494_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HDF3912091.1"
                     /translation="MKEQLIFNITNLVTVVFEAFVIHMFLSDFLGQKEGYIKVVRYAK
                     LGFIICLGFCNLITLNPKITMPLIFILIFSTSFLYKGNLKTRLFTTVLLSIFFILSEI
                     VVTSIFVLFVKEGFEIMLENNSIRVLATILSKIVFLLTCKIICLFKKDVHLDMPIKYW
                     LPLFLIPIFSLFLSVSIFDVSKFFSLESLKFLSLISSVGILYINFIVFYLFKFIIDKT
                     KLSMKYELLEKEIIHKEELRLSNECYKIIVEQTDSVVFEWNIKENKSFVSQAWTEKFG
                     YNNACKNIFKEIKDKDLVHSEDKAIFEGFLESIKKKNMHNQAVYRLKKSNGEYIWCRT
                     SITSIYNDENELLRVVGVIVDVDSDIKKYEELRTRAESDSLTNIYNKGTFEKLVEETI
                     VMNTGDKKDALFIIDLDDFKEINDNFGHPFGDFVLKTFADKIQTSFGSKDLVGRIGGD
                     EFVVYMQDYVTEVNLHKKAKELNRVLSDNYTDLSFSFDASVSIGIARYPQDGTSFFEL
                     FKNADRALYSIKASGKNSYCLFEEELYVQ"
     gene            complement(22406..23236)
                     /locus_tag="PC494_001588"
     CDS             complement(22406..23236)
                     /locus_tag="PC494_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HDF3912092.1"
                     /translation="MSQVSKNYFTTGEFAKICGINKKTLFHYDDIGLFSPELKKENGY
                     RYYSYHQLSIFGIISSLREVKMPLKEIKAYIDKRTPNLLIELLEKKTIDIKNEIEKLN
                     NIQALMESTISFTKSACNIDANTITLKEHEEEYLVKTPVTYKEQFLGDEEENFLYECI
                     NFMDNYELSDYGTIGSIIKGEDIINKDFESYSYLFTKVNKEYKKYPVSIKPKGLYVTA
                     YHKGSYETIYKAYEKLLNFFNQNNLRIGDFVYEEYLLYDISVRDSNEYLTQISAEVKM
                     "
     gene            23309..25036
                     /locus_tag="PC494_001589"
     CDS             23309..25036
                     /locus_tag="PC494_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF3912093.1"
                     /translation="MKKLIHFLKPYRVLIVVVLIFTFLQTLGTLYIPTLTANIVNNGV
                     VKGDIDYIVKTGLMMMIVAGITALSAVLVCKVSANLSSGFCRDIREAVFIKSQDLSIN
                     DFNNIGTASMITRSTSDITLIGQSVFMFIQLVLPAPIITVSGLFLAYSIDKAMTIIIV
                     VVMFLFMLSAFLVGKKLIKLFKMMQIKMDNMNRVLREVVTGVRVIRAFNRSRFEKKRF
                     DRTAIDYSETAISINKIFAVLMPIVMLIMNLGIVSIIWFGGMRVSNGNMEIGHIMALV
                     EYCILILFYLIMGVMVFMYIPRAGACADRVNQILDIEPEIVDGNGHKDTVSERGHLVF
                     KNVTFSYAQSEEPVLNNITFEAKSGEVTAIIGSTGSGKSTIANIIPRFFEIQSGEISI
                     NGQDIKKIPQKELRDKIGFVPQKAFLFSGTIEENIRYGKEDASIEEVKHAASIAQADE
                     FIYDMEDKYDSFVAQGGNNLSGGQKQRISIARALVRKPEVYVFDDSFSALDFKTDKRL
                     RKALKNEIKDSSAIIIAQRISTIMDANQIIVLNDGKIVGIGKHKDLLENCEVYKQIAD
                     SQLSKEELA"
     gene            25073..26935
                     /locus_tag="PC494_001590"
     CDS             25073..26935
                     /locus_tag="PC494_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF3912094.1"
                     /translation="MSEKRIDEQDIEVLSFEDGMSAEKAKDAKKTTKRLLKYMAKQKF
                     KILIIFISVLISSALTVLAPMVMGKAIDQLFNGIKTAVQTGTKFSVNFSTMGGIVSIL
                     LGLYLISAVFIYIQQYIMSGVAQNLVLSMRKDLSDKLNKLPLKYYDSHKKGETLSIVT
                     NDLEKVADSLQEGLMQLITAVVTVVGSIVMMISISVPLTIVSAITLLVSLGITVVIAR
                     KSQERFSENQKALGELNSNIEEIFTGQIVVKAFSKEKDTIRNFKILNQNLYNASRKAQ
                     FSSYAISPIIRFINLIGYVIIAVVGGIFASTGAMTLGSIQAFIQYVNQASEPTTEISY
                     IVNMLQAAIASAERVFTVMDEVEEIKDEESSKVISMPKGKVQFEHVKFGYSDDFILMK
                     DININLNAGDKIAIVGPTGAGKTTLVNLLMRFYEIQGGRITIDGVNIKDLKRGELRTM
                     FGMVLQDTWLFNGSIKENIAYSKSDATMDEIVRAAKSARVDHFIRTLPQGYDTILTED
                     ASNLSQGQKQLLTIARAILSDPSVLILDEATSSVDTRTEVEIQKAMNNLMKGRTSFVI
                     AHRLSTIRDADLILVMKEGTIIEQGSHKELIEKKGFYEELYNSQFTSEYDEDVV"
     gene            27268..27957
                     /locus_tag="PC494_001591"
     CDS             27268..27957
                     /locus_tag="PC494_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyphosphate polymerase domain-containing
                     protein"
                     /protein_id="HDF3912095.1"
                     /translation="MNKKLNYRFEMKHKITEADVLALKSRLYPIMKKDENASKDGKYL
                     IRSLYFDTPEDKALLDKLNGVAIREKFRIRFYNNDCSYIRLEKKIKHYNMTSKLSTNL
                     TKKEVINILNNDIEFLKESTNCLLREFYLKLKCERLEAKSIVDYNREAFIYPVGNVRV
                     TIDSDIKTSVNSVDLFNKDLPTVSVIDENMTVLEVKYDEFIPDFIKDLIQINKTTSTA
                     VSKYASSRLYI"
     gene            28053..28739
                     /locus_tag="PC494_001592"
     CDS             28053..28739
                     /locus_tag="PC494_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4956 domain-containing protein"
                     /protein_id="HDF3912096.1"
                     /translation="MILIMTFNDIFKSSFIENVSGFSFVDSALALGSAFLVGLFIYMV
                     YKKTYMGIMYSRPFNVSLVALTMLTTFVILAVTSNVVLSLGMVGALSIVRFRTAIKDP
                     MDLVFLFWSLGSGIVLGAGLIPLAVMGSIIMGLILIFFSNKTISETPYILMVNCNNED
                     SEDIATDKIKKVFTKYQIKSKSVTPEKGIELVFEVRMKDGETSLINDLSQVDGVTNAV
                     LVSYNGDYVA"
     gene            28756..30663
                     /locus_tag="PC494_001593"
     CDS             28756..30663
                     /locus_tag="PC494_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CotH kinase family protein"
                     /protein_id="HDF3912097.1"
                     /translation="MKDKKFTLLISIMIIFLCAVVGVYSTSSNKSVDLYSDVYIEKYF
                     NRDKVMEVNIEIDESDLKDMNENAIKEEFKVAKVTVDGDTYGNVGIRTKGNSSLISVA
                     NSDSDRYSYKINFDKYNTSQSMEGLTQLNLNNCYSDPSYMREFLTYSICEEMGLATPE
                     FAYAKVSINGEYHGLYLAVEGLKESYLENNFGNVTGDLYKSDEGSSLQYKGDDPESYS
                     NLIVESDKKTADWSKITKLLKSLDTGEDIEKYLDVDSVLKNIAINTALLNLDSYQGSF
                     AHNYYLYEQDGVFSMLPWDFNMSFGGFSGFGGGSQSIAIDEPTTGNLEDRPLISSLLK
                     NETYKTKYHKYLEEIVTKYLDSDYLENMTTKLHDMIASYVKEDPTAFYTYEEFEKNIT
                     SSIEDSSDNKGFGNKGFDNNNSNNSDSNNNSNSENKHSGNQSDEKEVNAELTSSVVKA
                     NTDNENKNKTTNDSESKNNTDKDKSGNDNNQKLEGPMGKGGKSIPGVLEVAEDMSKTI
                     KSQLSGETSSTKQNSGDESSSGIKGSEKFDEDMSGMPEPPEGMDGKMPPGMGNMDKGD
                     MNGKNGNMNMDRNQDNPREAGGFGNRGGGSVSKTTTYFKLILGGASMIIMSIMLVGVS
                     RVKRRRFIKSK"
     gene            31115..31804
                     /locus_tag="PC494_001594"
     CDS             31115..31804
                     /locus_tag="PC494_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3912098.1"
                     /translation="MLQKVLWKFLKLVVGLFICSVGIVLTINCNLGLSPWDVFHQGLS
                     NHIGITIGTASIIVGSIVVIADVVLGENVGWGTVFNMLLIGFFMDLLLYSNLIPEADN
                     LFVGIIMLILGLVLLSVGMVFYMGSGLGSGPRDGLMVAIQKKTGKSLKLIRGTIEVGA
                     LIVGFLLGGKVGIGTIISAFGLGYFTQMVFGLFKLDCSKIKHRFIVDDIKFIKVYMSG
                     EKKAAVQNIVK"
     gene            32240..32779
                     /locus_tag="PC494_001595"
     CDS             32240..32779
                     /locus_tag="PC494_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007286148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF3912099.1"
                     /translation="MDIGEKIKRLRTEKQLTQEELANRCELSKGFISQLENNLTSPSI
                     ATLIDILEILGTNLREFFNEIDDERISFTKEDMFETEDEDLKYKLKWLIPNSQKNEME
                     PIIITLYPGGQYKEEKPHEGEEFGYVLAGSIYVHIGEKKNKVKKGESFYFRPKANHYI
                     SNEGKTTAKVIWVSTPPSF"
     gene            32798..33841
                     /locus_tag="PC494_001596"
     CDS             32798..33841
                     /locus_tag="PC494_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011721317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF3912100.1"
                     /translation="MVENIIELRDISKHYEELTVLDNFNLDIKKNEFLTLLGPSGCGK
                     TTTLKIIAGFEYADDGKVLFEGKEINNLPPYERQVNTVFQKYALFPHMDVYENVAFGL
                     KIKKTPKDVIDAKVKEVLKLVALEGFERRQVESLSGGQQQRIAIARALVNEPKVLLLD
                     EPLGALDLKLRQEMQIELKRIQKKLGITFVFVTHDQEEALTMSDTIVVMYKGKIQQMG
                     TPQDIYNEPKNSFVAKFIGESNIFDGIMIEDYKVNFCNRDFECVDKGFEKNENIEVVI
                     RPEDIKMVKPEEGMLKGKVTSTVFKGVHYEIELNENGRLWILHNTKNAEVGTELGMDI
                     YPEDIHIMRKENN"
     gene            33843..34679
                     /locus_tag="PC494_001597"
     CDS             33843..34679
                     /locus_tag="PC494_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF3912101.1"
                     /translation="MKRKSFLAYPYVVWSAIFVIIPLILVVFFSFTKESGGGYAFTLE
                     NYKEVIDPIYMKVFGRSILLAGGATLICLIVGYPVAYIISKARVSRRGSLILLFILPM
                     WMNFLLRTYAWVAILGKNGLLNTFLGWFGIQPLAILYTNFAILLGMVYNFLPFMVLPI
                     YTALSKMDNDLINAAHDLGANNMTVFRKIIFPLSLPGVMSGITMVFMPAVTTFAISRL
                     LGGGKIMLVGDLIEQQFTVVGDWNFGSAISIFMMIVILISMSIMSKFGDESDKEGGGL
                     LF"
     gene            34784..35458
                     /locus_tag="PC494_001598"
     CDS             34784..35458
                     /locus_tag="PC494_001598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF3912102.1"
                     /translation="MARWNGFTWKWYGQLLQNESIMSALYYTIVIAILASVISTIVGT
                     ISAIGIHKMRGKSKKLILNVNYLPILNTEIVTAVALMSLFVFVKMEFGFTTMLLAHIM
                     FCLPYVILSVLPKMKQLPDNIEDAAMDLGATPIYALRKVILPQIKPGIVSGFLIAFTM
                     SIDDFIISFFNAGNGVSNLSIEIYGMARRGIKPEINALSTIMFAVVLGLLLLANKKES
                     IVRGIK"
     gene            35458..36510
                     /locus_tag="PC494_001599"
     CDS             35458..36510
                     /locus_tag="PC494_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spermidine/putrescine ABC transporter
                     substrate-binding protein"
                     /protein_id="HDF3912103.1"
                     /translation="MIKFKKAISLIAVGMMTVTLFTGCNKATDSTKVLNVYNVGDYID
                     ESLIDKFEKETGIDVQYSTYDTNEMMYQKVKSGSTHYDLVFPSDYMVEKMKNEGLLEK
                     LDFKNIPNMKYLDKSFLNPVYDKTNEYSVAYMWGTLGILYNKKEVKDPMDSWNILWNP
                     KYKGNIMMFDSVRDTIGITLKKLGYSMNSVNPKEINEAKNLLMKQKDLVLAYVNDEGK
                     DRLLGGEVAMGMLYSGDAVTLMEQNPDLDYAIPKEGTNKWVDAMCVPTTAQNKKEAEL
                     FINFLLDPENAKVNAEYIGYSTPNTGALKLLDPEITQNPVAYPSKEVLDKCETFEDIG
                     ENIKLYDKAWIELKSK"
     gene            36740..37588
                     /locus_tag="PC494_001600"
     CDS             36740..37588
                     /locus_tag="PC494_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HDF3912104.1"
                     /translation="MNRINKKIDLLILALLVFIFLIVGIVILSIRTENKLNVFIMLAI
                     IFFIIMLTYLSNSVVGLITSSIIIFMYTSYILYNNITHNMDVEFISYMWIIATPVSSI
                     IMGNLNKSINELQNTNKKLSEQYKELVTIDSETGLRNLKIFYNDVNMEISKSIRHNTD
                     FSLMIVKLPYYGNLQTIFGENKTNKIVKYIGSNIIECTRNEDIIYSLQKDMIGILMPN
                     TSLEGSKVVKDRIKKRIKELNLDLNNRGKYVNIDVKIAFLQYKSSFGDSINFKNIVEE
                     ELQYDV"
     gene            37578..39242
                     /locus_tag="PC494_001601"
     CDS             37578..39242
                     /locus_tag="PC494_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HDF3912105.1"
                     /translation="MMFKIFNKSLLKLVVVLSIVLTISNFSLSSYASEITSSTDKVLI
                     IYDSKKETAYNRDILNIMRTLLGRFSSDIELLKLSNYDGEINKNYYSHIFILGINENS
                     YNNDKNTKNLISSLNSYKGTICWLGYGIENLLEHKKYNLDYVGKTNNIVSVNYRGKSY
                     NLDEHYVFNIVESKDTSNKVIGSINDTLNKYPYIINDKNLFYVSKLDLDGVLFYIFCD
                     SLNDIFNIKTFDKGRIFVRIEDVHAFREPKNLVEIADYLSSKNIPFTIALIPAYVNPK
                     NHKVITLSESPEIVKAIKYMQDKGGTVILHGYTHQYKKEEVSGEGYEFWDGKKDEPLK
                     ENMKIFVKDRVLNGLRVCIENGIYPLAFEAPHYAMESEGYKELKKYFSTYIGQHQNND
                     KKFSTNTYPYIIRDTEEFNIFIPENLGYIDPEDKFTFQNIKENLDKLSIVRGFSGGFF
                     FHSYLNIEYLKNTIEYLEKQNIEFMNLRDFNNWVKVDEIQIRNNGDEIIVNYDKDLDE
                     LTKSDTRFKSISNISKVLIFIVSISVLIFVIIFIYFKRIDKKKFLK"
     gene            39291..40547
                     /locus_tag="PC494_001602"
     CDS             39291..40547
                     /locus_tag="PC494_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003362983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HDF3912106.1"
                     /translation="MRDLNVSEYLFVFSLFSIWSLLLINIILAMGGYIFYFKNFDKEI
                     KEIDEYPMISILVPAHNEAKVIGRTVESLLLLNYPKSKMELIVINDNSSDNSKEILEN
                     IKDRYNNYNFTIINTDSLTGGKGKSNALNIGYTISKGDFIAVYDADNTPDKNALRYLV
                     QTIVMNDELGAVIGKFRTRNKNKNLLTKFINIETLSFQWMSQAGRWQLFNLCTIPGTN
                     FILRRSIIEEIGGWDSKAIAEDTEISFRIYKLGYKIKLVPQSITWEQEPETVKVWIKQ
                     RTRWAKGNIYVLMKYIKNIFKQGRNKIVFDIAYFFSVYFLFLTSVIISDILFVLSISK
                     LVEISIPINFFLIWILSYLLFIIEVSISLTIEKGEATIENIFIVAIMYFTYSQLWLFV
                     AIKGMIEYLKDIIFKREVKWYKTERF"
     gene            40570..42651
                     /locus_tag="PC494_001603"
     CDS             40570..42651
                     /locus_tag="PC494_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cellulose biosynthesis cyclic di-GMP-binding
                     regulatory protein BcsB"
                     /protein_id="HDF3912107.1"
                     /translation="MKKFIISIISLVLFFSNISLIYKVNADETKVKNYKFERDITIDG
                     VIGSNSTFFEVNKNWDIEEVLLHLNFSKSQILNGDVSSLTVLINNVPIKSIKLNAKTN
                     YKNTLEVLVPKDYIIQGYNEIKIKTYKTISDKICQDDSNTGNWMVIHKESYISIRYKQ
                     KKVENSINEYPYPYAEIENNHKLDTTIVVPDNMTRGETTAVFNLASAFGKITKNDDLK
                     LDVKLYSEMKNWSDDNIIYIGKPENTAEEILDILSIKEQTLLSSNCIIKQVDSPYNKN
                     KKMMVVIGSNEDDLIKASNLLIENRLSNQVLSSSVLVNKETNIKINREQKLNLGHLTL
                     KDLGYSDFLLEGAFNQQALFDVKIPTGKVLDDGSKIILNLRYSDNLDFEKSLVTVSIN
                     DVIVGSKKLDRSHSNNDKLELKIPKDIDNKNYYQVKLTFNLSIKNSNCVTRESNNPWA
                     YVSNNSYLALSTKENETLSFENYPYPFVRDDEFNDLTVIMPDYSGSQAMTWMFRLGVT
                     LGANINSHNGNINVIRGKEFSDKYKDTNIVVFGVPHNNSVIKMLNNNLNIKFDKNYSN
                     FISNDKISFIDDYGKNISTIQLIKSPYNNQKNIMVISSMNEKNLYLGMDYLLNKSKVN
                     DLKGDTLIIDEYGEVEDLAYNLKSKKEVKDSSWNMSINKTTKVFLMISFITIIIVMIL
                     SMLYIKKYKRR"
     gene            42688..43773
                     /locus_tag="PC494_001604"
     CDS             42688..43773
                     /locus_tag="PC494_001604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HDF3912108.1"
                     /translation="MRKYMNEFKLKRSILISLIILIFIFIVYFVSIELKDRSLVNNQY
                     KGKIKSANLSVDYEINQVMKDIDKLGLNTVNVPIIINVESINSDIMSIDNNSKEKAIK
                     LIKKLNKKGISTILEAYPWIENGKLYETDWNPINKKRFFYTWQNAILNELIIDVANPL
                     DVNVLNIGSNFVHLEEYQQNWGEIIDFVQSKFDGLVTYRTNWWYTKKDDLSSKLFYEQ
                     KLNNNFFDKLDFISIAAYFELSNKPVNTVDELISALHSSTVNNRGQNIKQEIYNLYKA
                     HRKPIFFGELGFSNRESASSQPWNHTPSKAVNGEEQARCFEAYKKVFENEDWINGFSV
                     FCVGKIDDEKNFYPSKESIKVIKSWYE"
     gene            43827..44951
                     /gene="wecB"
                     /locus_tag="PC494_001605"
     CDS             43827..44951
                     /gene="wecB"
                     /locus_tag="PC494_001605"
                     /EC_number="5.1.3.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine 2-epimerase
                     (non-hydrolyzing)"
                     /protein_id="HDF3912109.1"
                     /translation="MNDIKVMTVFGTRPEAIKVAPLIKELEKRENIKSIVCVTAQHRE
                     MLDQVIETFNINVDYDLDIMEKGQSLNDITCKILNKLPLILNKENPNIILVHGDTTTT
                     LATSLTAFYNKTLVGHIEAGLRTYDKYSPFPEELNRQLTGIIADMHFAPTNLARKNLI
                     SEGKPNNNIFVTGNTAIDALKMTIKENYNHPIIDEIGNDRMILLTSHRRENLGKPMKN
                     IFRAIKRIVDDFEDVQIVYPIHLNPKIRTIADEIFGKFPEKIHIIEPLDVADFHNFLN
                     KSYMIMTDSGGIQEEAPSLGKPVLVLRDKTERTEGIEAKTLKLVGTNEDRIYNSVSDL
                     LINKDNYVQMSKASNPYGDGNASKYIVDIIIKKFNCKYLN"
     gene            45029..46003
                     /locus_tag="PC494_001606"
     CDS             45029..46003
                     /locus_tag="PC494_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HDF3912110.1"
                     /translation="MARKLIKNLGKSKSVKRVKLLFKKIFITVFIVASIVAIFNITKY
                     FEELYKVRDLKSTKIEYYMDVADEAGDGKVQLSWKALLAIDMVIHDEDLSNIKKKDTL
                     DIGEKFIVEDKNGKGEKVYKVKKFNKVLSELKFDSSQKSRARKYMKDLEYTYLGNKQL
                     DSSDEKIKFIKKLEDSAIREYIDYGILPSITIGQAILESGWGNSKLTKQSNNLFGIKA
                     DKAWKGKSVEISTSEHYNEKIVASFRSYNSLQDSVKDHSLFLINNKRYRKHGLFEAKD
                     YISQAQALENAGYSTAEDKKGNRIYAELLIDVIRSYNLQLIDNKVETK"
BASE COUNT        18407 a         4673 c         7998 g        15068 t
ORIGIN      
        1 atattaatta agaatgatga aatatgaata aagattttac aaataaatct taagctatct
       61 tatttaattc taatacagga agaaggtaaa tgtatattga aaaaatcata gaaatagaag
      121 taaacaattt aaataaatac aaaggtttgc aaaagaagta atataattat atacaatgag
      181 gatgtgagta tgatgaacag actaaagcca agaattttag gtattagtat cttgtttatt
      241 attataatta ttttaacatg tggagctgtt ttcaagttta aatttaaatt agataataaa
      301 ttaaaagaaa ccacacatac atatttgtct gagtttacag aacacaatat aattaatctc
      361 aagacaagac ttagtggtca atttgacatg cttgaatcta ttgctaactt cataggaaac
      421 ttgaataata taaatgatga aatggtgatt gatttaatgg attctgatgt aaagcgaagt
      481 tctttaatta gaatgactat ctctacatta gatggggaat gttattctaa tgatggaatt
      541 acccataatg ttcaagatag agattatttt aaaaaagcta aaaatggaga aaagaatata
      601 tcagagcctt taaaatctat tgttaataat aaagaaataa tagttttatc taccccagtt
      661 tataaaagtg ggaaaatagt tggtgtttta agtggaattt atgattcaaa aaagttaaat
      721 gagttattag gattatctgc atttgatgaa aaagcagatg tttttgttgc aaagaaaaat
      781 ggagatatag ttgctcaaaa aacaaataaa aatagaaaga cgctatcatg tatatttcag
      841 ctttttgaca aagataattg tgatgaagat gattgtctaa aaactataaa agaaaatatg
      901 aaaaatgata agtctggata ttttaattat aacttagata atgaaaaatt tatgttaaac
      961 tatcagccac ttggagttaa tgattggtat gttttttctg ttgtgccaaa taaaatagta
     1021 tctattcagt cagagaatat atcttatgat gtatatattt ttgcattaga aatactacta
     1081 gttatattga tttttataat atatatagca tgtattataa ataataacac caaaattatt
     1141 ataaatgaaa aagaaaaatt taaagtactc actgataata tattaggagg ggttaaaacc
     1201 tgtttaaaag atgaatatat gactatgaca tatgtaagtc aggggttttt agagcttaca
     1261 ggttactctt gtgaagattt aaataaaata tttaaaaata gatttaaaga catgatttat
     1321 aaagatgatt tagacaagtt taattgtatt attctaaatc aattagaaaa acaagataaa
     1381 attgaagttg aatatagaat tgtaagaaaa gatggaagta taatttggat tttggagaga
     1441 agtaagtcta taaatgataa taaaggaagt gagtgtattc agggagtttt aactgatata
     1501 acagaactta agaaaataca agaagaatta gattcaaaaa gatttgaaat acaggctatc
     1561 aatgatagta ttgttggtgg aatagtgata actgagataa atgatgattt tgatagtata
     1621 tatttaaatg aaggttattt aaatatgatt ggatatacac gcaaacaact ggaagatgag
     1681 ctaaataata aattaatcaa acttattttt aaagatgata gaacagaatt aattaatagt
     1741 ataaacaaac aactcaaatt aagtgataca tttgcatctg aacaaagagt tgaaaaaagg
     1801 gatggcacta ttatatggat tttattaaaa ggaagaaaga tgatttatga taatggaaaa
     1861 tctgtacttt gttgtgttat tgtagatatt acttctgcta aattattaga gcaagaactt
     1921 aaaaagagtg aagaacgtca tgaaatcatt ctaaagcaga cgcaaaatat tataatagaa
     1981 tgggatatag aaaaagataa aatgaatata tcacctaatt ggtataataa gtttaaatat
     2041 gaccctataa ctgaaaacgc aacaaaaaat ataattaaat cagtagatat atatcatgat
     2101 gatatggata agtttatttc attaattaaa cttacttcac aaggtagtga gtatgaagag
     2161 tgtgaaatta gacttagaac tagagatact atttacgctt ggtttagtat aaaggcaaca
     2221 actttatttg ataataatgg taaaccttat aaagtagtag gaagtttgac tgatattgat
     2281 gaatcaaaac gagaagctga aaagttgaaa gaaagggcag aaaaagaccc tcttacagat
     2341 ctgtataata aaaaagcatc acaatcactt atagaggagt acataacatt ggataaaaaa
     2401 agaaaaggtg ctttaatgat tattgatatt gatgacttta aaggaataaa tgataattta
     2461 ggacatttat atggggatgc tgtattaagt gaaattgcaa atgacctaat aaatctattt
     2521 agagcaaccg atatagtagg cagaattggt ggagatgagt ttattgtatt tataaaagat
     2581 atttctgaaa caagagatat tataaataaa gcagaagaat tggtaaaaac atttgaaagg
     2641 tcttttttag gtaaaggacg aaattataaa atatcattaa gtgtaggaat tgctaagttt
     2701 ccacaagatg gtatggacta tatgacacta tttagaaatg cggatatagc tctttactca
     2761 gccaaaggga agggcaagaa ttgttataca ttgtatgata aaaaatttga taaagtccaa
     2821 tatataacta atacaagaaa tgcaggagat agtgataatg tagagatgtc ttttaaagaa
     2881 catatcacaa attatatatt tgatatacta tatgaatcaa gtgatataga agtggcagta
     2941 aatttaattc taagtattgt aggtaaacac tttaatgtga gtcgcatgta tatatttgaa
     3001 aattcagatg ataatcgagt atgtaaaaat acatttgaat ggtgtaacga aggtgtaacc
     3061 tcggaaatta ataatcttaa aaatatttgt tacaaggatt taggcaacta tcttttaaat
     3121 tttaatgcag atgggttatt ttattgtaat gatattgaaa atttaggtag tgatgtgaaa
     3181 aaagtactta agccacaagg catacgttca atattacaat gtaaaatttt agagggtaat
     3241 gaatttagag ggttcatagg atttgatgaa tgttcatata atcgtatgtg gactaatgat
     3301 gaagtgaaca ctttgacatt tatatctaaa acgctcagta tgtttttatt aaaaatgcgt
     3361 attcagagta agctagaaga gtctttaaca attcaaaaat ctgtgatgga taatatggat
     3421 atatgggcat atgttgttga caggaatacc tatgaattac tatttatcaa taaaaaaatg
     3481 cttgagtcag caccaaacac tcatgtaggt gatttatgtt ataaagcgat atggaataat
     3541 caagataaac cttgtaaaaa atgccctatg atatatttaa aagatggtga tgatacttat
     3601 aaatcattca tgcataataa aaagtttgag gtacaggcaa atataactac aactactttg
     3661 aaatggtttg atggtaaaga tgcatgttta atatttggaa gtgaaataac tagtattgaa
     3721 gctgaagaaa atacttaaaa tactgtgtta tatatatact taaaatcgca atttgaattt
     3781 attagactta aaatgtctat ataaatcatt taagttgtgg ttttaagtat tttttatgat
     3841 ataattaagc gttaagaaca aaattaaaag atacttttgt ataaaaaaat atttgttaaa
     3901 tatatattga gcaggtgata atatggaaaa taagttttta ccaataagca aacaagatat
     3961 gatagataga ggatgggaag aattagattt tgttctagtt acaggagatg cttatgtgga
     4021 ccatcatagt tttggaacag caataatatc tagagtttta gaaagtgctg ggtataaagt
     4081 tggaataata gctcaaccag actggagaac tacagatgat tttatgaagc taggaaaacc
     4141 tagacttgca tttctagtta atgcaggaaa tatggattca atggtcaatc attattctgt
     4201 aagtaaaaag catagagaaa aggatatgta ttctccaggt gggaaaatgg gttatagacc
     4261 agatagagct actatagtat attgcaataa aataagagaa gcatacagtg atgttgcaat
     4321 agtaataggt ggaattgaag cgagcttaag aagatttgca cactatgatt attggagtga
     4381 taaggttaga aagtctatgt taatagatag tggagcagat ttattagttt atggtatgag
     4441 tgaaaagcag attgtagaag tagccaatgc acttaatgat ggatatgacc caaaatacat
     4501 tagacatatt gatgggacat gctatatttc agatacattg gaagaaatat atgataaata
     4561 tatattaatt ccatcatata aagaaatttg tgaagataaa atgaagtatg tagaagcttt
     4621 taaaattcaa tatgatgagc aagacccatt tagaggtaat ataattgttc aacctcatgg
     4681 aagtaagtat ctggttcaaa ataagccaga aaaaccactt agtagagaag aactagatga
     4741 agtatatgga ttaccatatc agaagacata ccatcctgtg tatgaaaaat ttggaggaat
     4801 accagctata gaagaagtaa aatttagtat agtaagttca agaggctgtt ttggtagttg
     4861 ttcattttgt gcaataacat ttcatcaagg tagagcagtg caaagtagaa gtgaaaaatc
     4921 aattattgat gaagcaatag gaataacaaa tttagatgat tttaaagggt atatacatga
     4981 tgttggaggt ccaacagcta attttagaag accagcatgt aaaaaacaaa ttactaaagg
     5041 tgcttgtaaa aatagacaat gcttatctcc atcaccatgt aaaaatttag atgcagacca
     5101 cagtgaatac ttacatttac ttagagctgt aagaaaatta cctaaaataa aaaaggtgtt
     5161 tgtgcgttct ggaattagat acgattatgt aatggcagat aagaacaata aatttcttag
     5221 agagttgata gagcatcatg taagtggtca gttaaaggta gccccagaac atatatcaga
     5281 agaagtttta aagtatatgc aaaaaccagc aggaaaaact tatgataaat ttagacagaa
     5341 gttttttgct ataaatgaag aattaggtaa aaagcaatat ttgataccct atttaatgtc
     5401 tagtcaccct ggttctacct taaatagcgc tatagagtta gcagagtatt taagagatac
     5461 tcactaccaa ccagagcagg ttcaggattt ttatccaact ccagggactc tatctacaac
     5521 catgttttat acaggtattg acccgcttac aatgaagcca gtttatgttc ctaaatcaaa
     5581 acgtgacaag gcgatgcaaa gggctttatt acaatataga gcacctagaa attatgattt
     5641 ggtatactct gcgttagttg aagcaggaag agaagactta attggttttg gacatagatg
     5701 tcttataaag ccaaaaaatg aaaagcctta ttttaataga aataattcta aaaaaaatgt
     5761 atctaaagga acaaataaaa acaaaaaaac taatacaaat aacagaagta ataaaaatca
     5821 acaaaaaagt tcaactaaaa aaaagaaaaa acattaaagt ataaataaaa atacttaaaa
     5881 aagaaggatt attcgataaa ttaacagaaa ttagtataaa taaatataat tattttaatg
     5941 acgttacctt tgggaggaag agatgaaaaa gtatatttct ataatattat tagtggtgtt
     6001 gactatggtt gttttggtag gatgttcacc aggaaaagat aaccctaaaa ataaggagct
     6061 atcagttgtc aaacaagtaa aagtagctgt tccagatgga ctaccagcag tggcaatagc
     6121 taaacttgca aatgaaaatc cagagattaa agaaggatat gaaacagtgt atagcattga
     6181 aaagacacct gaagcgattt ccactagagt gatgaaaaaa gatgcagata tagctatagt
     6241 tccttcaaac atggctgcaa tagcgtataa taaaacttca tcatataata ttgttggaac
     6301 tgtaggaatg ggttcacttt atttggtgtc aacagaaaat ataaaagatt attctgattt
     6361 agttggtaaa gaagttggat gtactggaaa aggacttact ccagacataa ctataaaaag
     6421 tcttttgtta caaaaggata taaattattc agatataaaa tttaattatg taaattcagc
     6481 aagtgaactg gtaccattat tggctactgg taaagttaaa acaggtattg ttccagaacc
     6541 tgcacttagt gctttgatgt ctaaaaatcc agacataaaa attataaaaa gtttaaatga
     6601 ctcatggaag gaagtaagtg gttcaaaaga tggttatcct caatctactt taattgtaaa
     6661 gtctgaattt ttaagagata ataaagattt tgttgattct tttgtaggtc aattatcaaa
     6721 tagtatagat tgggcaaaca aaaatcctga agaattaggt gcatattctg aaaaaataaa
     6781 aatatctact gaatcaaaga taataggaaa atctcttgaa agagctaatt taaaatatat
     6841 tccagttaag gacatgatta aagattataa aaattactat gagaaattag ctaattttga
     6901 tgataagaca ttaggaggca aagtaccaga tgaagcaata tactttgttg agaaataaaa
     6961 aaataaagaa caatttatag ataaaatgga ggtaacactt tcttgtgtta tcctcttatt
     7021 tttatggcaa attattgctt taaaaattga taatgatatt tttttaccaa cagtaggtca
     7081 agtatttaat agtataaaag agattatgct aaattctagt ttctatatag atatacttta
     7141 ctctatgggg agatgttttt ttagtttttt actggctatg atttttgcta ttatactttc
     7201 aatagtgtct tatttaaata gattttttag aaacttatta aagccaatca atgctttgac
     7261 acgttcaata ccaactatga tattggtagt acttgcactt atttggtttg aaaaggatag
     7321 tacccctttt atagttggat ttactatagt ttttcctata ttgtatgata acgttttggg
     7381 cgctatattg aatatagaca agaacttatt agaaatggct aatgtgtata aaataaggtt
     7441 tatagataag gtgttaaaaa tttatttacc agccataaaa tttcaaatta tatctatact
     7501 agtatcaaca ttctctttaa gtttgaaagt tgctatagca ggagaggtat atagtcaacc
     7561 tacatatggt attggaacta tgatacagac tgaaaaaatt aactttaaca catctggaat
     7621 atttgcatgg ataattattg ttcttttaat atctgctatt ttacaaatag ctcaaaagtt
     7681 tttagcaagg agagcttttt tatggaaaag ataaagttga gtattgaaaa tataaataaa
     7741 agatatgata gtcgtattat atttagagat tttaatattg atttttatgt aaatgaggta
     7801 aattgtatcc ttggaaaatc tggttgtgga aaaactacac tcttgaacat aataagtggg
     7861 attattaaaa atgacaccaa caatctaaat atcaaagaaa atttaaatag agtaggaaat
     7921 aagcttgaag ctagttacat atttcaagat gatagactta tagactggtt aacagtagaa
     7981 gaaaatataa agatagttgt aaataaatac tataataaaa ctcaattaaa taaaatttgt
     8041 gatgaatact tggaattggt tggaattagt gattataaaa aattctatcc tcagatgctt
     8101 agtggaggta ttagacaaag agtaaatatt gctagagctt ttatatatcc atcaaaaaat
     8161 attataatgg atgaaccttt taaatctatt gatgcaaaga atacacagct tataatggat
     8221 aatttcagaa atatattaag aaaagaaaaa agaactgtgt tatttgtaac tcataatatt
     8281 gaggaagcat tgtttttagc agataggata tttattttag gagactctcc aattagaata
     8341 aaaaaaatat taaaaaattc taaggaattg gaaaaaaatg aagttttgaa gttgatatag
     8401 agttataata atactgtcgt tttaaaatat atttggttaa aatctataag actatattaa
     8461 aatagtacag aatattcaaa actgtgtata atgttcgtat tttataaaaa ggaagtgaat
     8521 gtatggttaa gactaatgct atgagaatat tagattcaaa taagattgat tataaagtaa
     8581 tgtcttatga agtgaaaagt gaacatgtgg atggtgttga ggtggcacat gatataggaa
     8641 gagatgtaaa tgaagtgtat aagacattag taactcaagg agttagtaag aatatatatg
     8701 tatatgtaat accagtacat gaaaacttag acttaaaaaa ggctgcaaaa gtagctaaag
     8761 agaaaagtgt agagatgatt catgtaaaag atataaataa gcttacaggt tatattagag
     8821 gcggatgttc tcctataggt atgaaaaagc tttataaaac ttttgtaaat gaaagtgcaa
     8881 agaatttaga tacaattatt gtgagtgcag gaaaaatagg atatcaaata gaactatctc
     8941 catttgattt acaaagactt ataaaagtag aatttgtaga tgtaataaaa aaataagaat
     9001 tacatataaa atatagagct tatattctta ataataggtg ttgtagtatt aataaaatga
     9061 ataataattt taaaataaat attcagttac ttatgtgtaa ttggtataaa aatattgaga
     9121 aattttaaaa acaatggtaa agtgtaagta taatcacgaa tattttttat aaagtaatgg
     9181 agggatgttc gcttgagaaa aataaaatct gaacaaatcg tcgagcaggt aaaaaaactt
     9241 tgtatagaag cgagcctata tttaggagaa gatgttttaa gctgtataaa agaaaaagcg
     9301 aaaagtgaaa agagtgaagt tggaaaaaat atattgaata tattagttga aaatgctgaa
     9361 atagctaaag aaaaaaatat accaatatgc caagatactg gtatggctgt attttttgtt
     9421 gaaataggac aagaagtttt aattgaagga gacacactta ctgatgctat aaatgaggga
     9481 gtaagacaag ggtatgaaga aggctactta agaaaatctg ttgtaagtcc aattaacaga
     9541 gtaaatacaa aagataatac acctgctgtt attcattatg atatggtaaa aggtgataaa
     9601 attaaaatag aatttgcagc taagggattt ggaagcgaaa atatgagtaa gatgaaaatg
     9661 ttaaagccat cagatggatt ggaaggaatt aaaaaattca taatagatac agtttcagaa
     9721 gctggaccta acccatgccc tcctatggta attggagttg gtataggtgg gactgtggac
     9781 aaatgtgctc aaatagctaa aaaggcactt tttagagaac taggtgaatt taataaggac
     9841 gaaaatatag caaaacttga aagtgaacta ttaacagcta ttaataaact tggtatagga
     9901 cctcaaggct taggtggtac tacaacagct ttgggattaa acatagagac ttttcctaca
     9961 cacatagcag gtttacctgt tgttgtaaat ataaactgcc atgcatcaag acataagaag
    10021 gtagtaattt aggaggaaaa taaaatgata aaaataacta cacctgtaaa tgaaattgat
    10081 atagcaaaat taaattgtgg agatacaatt agtttgagtg gtatacttta tacagcaaga
    10141 gatgctgctc ataaaagatt gatagattgt ataaataaag gtgaagaatt accatttgac
    10201 gtatatggtc aaggaatata ttatgtagga cctactccta caaagccagg agaagttata
    10261 ggtgctgcag gtccaacgac gagttataga atggatgatt tgactatacc tcttttagaa
    10321 agaggtctta gattgatgat aggcaaggga aaaagaagtg atgaagttat agaaggtatg
    10381 caaaaatacg gagcagttta tcttgctgca ataggaggag ctggagcata tatttcaaat
    10441 tcaataaaat catgtgaaat tattgcatat gaagatttag gagctgaagc tataagaaag
    10501 attgtagtag aagaccttaa gcttacagta gcaatagata gctatggaaa taatatatat
    10561 gagcaaggtc gagcaattta tgaatgtaaa taatgtttag aaataaatat gaatatcaaa
    10621 attaaaaata gttgtgtata ttttaaggag gaaaattgat gtctaaggat tatgcaaaat
    10681 tggcattaga aatgcatgaa atcaacaaag ggaaagtaag tgtagaaagc aaggtagaag
    10741 ttaaaactaa ggatgattta tcaacagcat atacaccagg ggttgctgaa ccttgtttaa
    10801 aaatacatga aaatcaagat gatgtttata gatacacttc taaagggaat ctagtagcag
    10861 tagttagtga tggaagtgct gtacttggat taggtaacat tggtgctgaa gcatctatac
    10921 ctgttatgga aggtaaagct atattattta aacaatttgc agatgtagac gcttttccaa
    10981 tatgtttaaa gactaatgat gtagatgaga tagttaaatc tgtagagttg atggagcctg
    11041 tatttggagg tataaatttg gaagacatat cttctccaag atgttttgag atagaagaga
    11101 gattaaaaaa atctttaagt atacctgttt ttcatgatga ccaacatggg acagcaataa
    11161 tagttgcggc agccataata aactcaataa agttaattga aaataaaaaa atagaagatt
    11221 tagaaatagt tataaacgga gcaggagctg ctggtatagc catagcaaag atactactta
    11281 atatgaatgt taaaaatata atcttatgtg atagaagtgg agcattggaa gctagtatag
    11341 aaaatctaaa ctatgttcaa aaagaaatgt taaaagtaac aaatataaga aatgaaaaag
    11401 gacctttaaa agatattata aaaggaaaag atgtatttat tggtgtttca ggtccaggag
    11461 ctgttacaaa ggaaatggtt gaaagtatgt ctgagaagcc aataatattg gcaatggcaa
    11521 atcctactcc agagataatg ccagaagaag caaaattagg tggagcattt ataatgggaa
    11581 caggtcgttc agacttccct aatcaagtca ataatgtact ggcttttcct ggaatattta
    11641 gaggtgcact tgatgttaag gctaaagaga taaatgaaga aatgaagata gctgctgcat
    11701 atgcaattgc taatacaata agtgatgaag aaatatgccc agagtatata ttaccagatg
    11761 tatttaataa gaatgtagta aaaaatgttg ctaaggcagt taaagaagca gcgataaaaa
    11821 ccaaagtaaa tagaatataa atttttatat gttcatatat ccttatatta tcgggtatat
    11881 gggcattttt attataggtt tatactcata tatccttact tttatataca tatctttatg
    11941 attaaaggtg ttagaaaatg tagtaaattt tatactatca gactctatct ttattacttt
    12001 agtagataca tggttgtaaa ggtttataga aaaaaatata ggaaggcaga tttttattgt
    12061 tgcgtatata tgagaatgat ataatatgaa tattataaat taataaattt aaatttatgg
    12121 aggtacaaga gatgatggaa tataaagtta atgaccaaga acttaatgct tcaatgttta
    12181 tcccattcgt caacaggata tggccaggag attatgatat ggataaaaca cagactgcat
    12241 tatcaaaaac tttgaatata actgcttatg atgataaagt gcttgtagga tgtctgcgag
    12301 ttctttcaga tggttattat tttggaacaa ttacagaatt gcttgttctt ccagagtatc
    12361 agaaacaagg cattggtagt aagcttttcc agcttgctaa agagaacacc ccaactatgc
    12421 tatattttgg tgcacagcca ggagtagaag agttctatga aaaaaatggg tgccaaagaa
    12481 gtctgcaatc ctacataata aaaaagaaag atagttatta aagttccagc tttcaataat
    12541 cttaaaagta caatatttta gtggaagcat ttcatttttt attactaata tgacataaac
    12601 atgtcatatt agcattgata tacttttaat atggttaaga gccaaagaaa aatataagga
    12661 gtgatttaaa atggaagaaa ctaaattttg ccaatgctgt gcaatgccaa tgggacaaac
    12721 tgatgaatta tatgggacaa ataaagatgg aagtaaaagt actgattatt gtagttattg
    12781 ttttaaagat ggtgagttta cagctgatat aagtatggaa gagatgatag aagtttgtat
    12841 ccctcatatg cttcaaagta ataaggatat gactgaagat gaagcaagaa caatgatgaa
    12901 caatttcttt ccaacattaa aacgctggaa ataattttat gcaaaattag ttatatgcaa
    12961 aacatgaaat atggtgttga gaataagggg tggtgtgctt tatagcatac cacctgtttt
    13021 gttacttgga gttcagttat tttcctaaat attttaaata tactatttta gataagttcc
    13081 ctcttcatct tgataaatta atcctttttt cataagcact ccaagagctc gtttaaaatt
    13141 tttcttactt gaattaaata atatagaaat atctttagga tcagatttat cattaaatct
    13201 catatatcca tcagaacctt ctaaataact taaaatctta ttttctaaag tatcaagttc
    13261 atcctttcta tttcctctag gagaaagacc aagttttcca tcttcatata tttttatgac
    13321 atgtaaattt tcaagaacat caccagtttt tagttcagta aagtactcat tatgaagtat
    13381 tacaccagca tatttattgt ctacacatat cattgcagaa ttattagttt ggaatccata
    13441 tacaactcca gttacaatat ctcctacatt gtaagtatgg tctgttaata aatatgaatc
    13501 tatatctgta gtagcagcaa ttcttttgct tttgtctaaa tatatataaa ataaatattt
    13561 ttcgtctcta aatagtggat aagtcttagc tttaaaagga actaatatgt ctttaggaag
    13621 tcccatatct ataaaagtac caatgtctgt attatcaact acttttaaat gtgctacatc
    13681 cccaacctta gctaaaggcg gtattaaagt tgcagcagtt ctgtcatcag aatctttaaa
    13741 tatgaaagca tttacttcat cacctatgtt tatttcattt tttccgatta atctattatg
    13801 aagaagtata tcgtcttttg tgttattagt ttgtccatcc aaaaaatatc caaattcagt
    13861 ttttcttttt actgtaagtt tattaaaatc acctatgttt atcaaattaa aatcatcctc
    13921 tcattttata tttataattt agccataata tacttatgta gtagtttgtc acagtatcta
    13981 tattagtatt agtgaaattt acaataaata atatagttat ttatgtattt ttcaattctc
    14041 tagcttctta tatagtataa actccaattt cttttttgtc tttaggtttt attaaaattt
    14101 ttacaaaata agttaaaaag tattgaaata aaatttcttt taaagtataa ttggtatata
    14161 ccaaaattgg tatataccat atcgaaaagt ggtgactata tgaaaatagt aaataaatct
    14221 agtaatatac cattgcatac tcaattaagt tcaataataa gagagatgat agaaactggt
    14281 gagcttaaag agggtgatgc aataatgcca gaaagagaac tttgcaacat acaaaatgta
    14341 agtcgtatga cagtaaataa aaccattgtt ggattagtta cagaaggact tctttatagg
    14401 gtacaaggta aagggacatt cgttgcaaag caaaaaaaga agtatcagtt ttcaaatgta
    14461 aaaggtttta ctgatgttat gaaagaaaag ggagtaaaca taaaaacgga tatattatcc
    14521 tttgagatgg aactaccaga tgatttagtt aaaagaaagc ttggaataag tgataatact
    14581 acaaatatat ataagattgt cagacttaga tatactgatg gagagccatt tggattagaa
    14641 atagtatatc tatcagaaga aatgtgtaag ggtctaacaa aagggatatt ggataattct
    14701 tcattatata gggttttaaa tgaaaaatat ggctataaga tacaaaaagc tgaacaggta
    14761 atggagccag taatactttc agatgaagaa agtaagcttc ttgaaacaga tgaaggtgct
    14821 ttagctctta aacttcatag aaattcctat aatagagaag gtagccctat agaatatacc
    14881 atatcaatat ttagaacaga taaatatcaa tatgaaatag tattgagtga gtaggtgaat
    14941 aatatgaaat gtttaattaa tggaaagata atattaaaaa atcaaatctt agaaaataaa
    15001 gtattagtat ttgatgaaaa aataattgat atagctgata gtgtaccaaa agattgtgaa
    15061 gttatagatg ctgatggaaa atatatatct ccagggctta ttgatattca tatacatgga
    15121 aacatgggaa aagatacaat ggattcgact gatgaatcta ttgaaacaat ttcaaagtca
    15181 attatgagac atggagtaac atcttttctt ccaactacaa tgactatgga taaagaacat
    15241 gtttatgatg cacttgaagt tattaaaaaa gcccaaaata gaaagcttga aggggcacaa
    15301 gtattaggag cacatttaga aggacctttt ataaatgaga attataaggg agcacaaaat
    15361 gaaaaattta taataaattc aaaatacgaa tttataaaag aatataaaga tgttataaaa
    15421 gttataactt atgctccaga aaaagatatt gattttgatt ttactagaga aataaaaaga
    15481 tgtacagata tagttttatc tattggtcat agtaatgcaa attatgacca agctaaagaa
    15541 gctataaatt taggagtaac taatgtaact cacatgttca atgcaatgac tggtttaaac
    15601 catagagacc caggcgttgt tggtgcagca cttacaacta atgtgtacag tgagttaata
    15661 gcagatacaa tccatataaa taaagattta tttcaattta tactaaataa taaaggaaaa
    15721 gaaagactga ttttaataac agattctata gaagctggtg gtcttgaaga tggcaattat
    15781 tctcttggag gtcagaaagt catagttaag ggtaatgaag ctagacttga aaatggagca
    15841 ttagctggaa gtgtgttgtc tttaaataaa atggtattta acttcttaga taatacaaac
    15901 cttaaagtga atgaagcaat taatttagct tctttaaatc cagcaacatc tttgggaata
    15961 aatgacaaaa aaggaagctt agaaataggt aaggatgcag atatagctgt atttgatgag
    16021 aatttagatt gtaaaatgac actttgcttg ggggacgtag tatataaaaa tatatagtat
    16081 acaaaacaaa ccttaaagac agtaaaaaca atataaaaaa taataaatta aacttacatt
    16141 agtaaaagta gtagttaaaa tttaggagga ataagatgag agtattagtg tgtaaagatt
    16201 atgatggaat gagtaaaaaa gccgctgaaa tgatagcagc tcaaatagtt ttaaaaccaa
    16261 attcaatact gggactagct acaggaagta caccagtagg tatgtataga gatttagtaa
    16321 aaaaatacaa tgataatata gtagattttt cagatgtgat gagctttaat ttagatgaat
    16381 attataagtt accaatatct aatgaccaaa gctatgatta ttttatgaaa gagaatctat
    16441 ttaatcatgt aaacataaag ccagaaaata ctcatctacc aaatggaatg gctgatgata
    16501 ttgaaaaaga gtgtatgaac tatgaagctt ctatagatgc agctggtggt atagatgtac
    16561 aagtacttgg aataggtcgt aatgctcata taggttttaa tgaacctgat actaaatttg
    16621 caaagagaac tcatgtagtt gaacttacag agtctacaat agaagctaat gcaagattct
    16681 ttaaatcaag agaagatgtt cctaaaaaag ctgtaagtat gggaataggt tcaatattga
    16741 agtctaagaa aatattgctt ttagcttcag gagaagaaaa agctgatgca gtatataata
    16801 ctgtttatgg agatataact ccagaagttc ctggttctat acttcaactt cataaagaca
    16861 ctatagttat agtagatgaa gcagcagcaa gtaaattgaa tccaaaagat tataaattag
    16921 tataagaata gaatgtagtt taagtaaaaa atagctatca ttgagtaatc aaatttattt
    16981 aatgatagct atttttattt aaatttttta cttcttttta tttaaattag ttattattgt
    17041 ttaaattact tgcttattac tttttacgaa aactcgttat caagaagtat ccaaataaga
    17101 tgttaaaaat tattatgttt agtgggattc tatcaagcat aataaaatta cctataattg
    17161 ggatattacc aactggaaac ataaagaaga atacaggcat cagtgatagt aaaaaagatg
    17221 gaaaacaaag aagaagtaat cttggaatat caatatacca actaccatcc tttttgtatt
    17281 ctctaatcaa taattcagtt cctagtaata aaccaatacc accagaggaa attaaattaa
    17341 taaaaatgta tcttttaaag tcttgcatat aaccagtgta aaattgagta tagaaatcat
    17401 aatttaattt aacggctaaa aaatacataa gcaatagaat gattaaaaat aaaagatatc
    17461 taagagcttt tttcatttta aattctccct tcagaaatac tttatttagt tttattttgt
    17521 tggaatctga ttttatcatt tagtttaaga aatccataat attagtgaag aatgaaataa
    17581 gtattatata tgaataaata tttttagaat taaggtgaat tgtagtgctt aatataacta
    17641 taatattaat tgtttgaata ttcaataaaa agtttgaaaa atatcaattc tgatataaac
    17701 tgaataaata cagttgaata ttaaattatt attttatcaa aaatatgcaa agtactacac
    17761 cttcaaatat cacctaaagt aattaaaagg caattaaggt gaagtagttc aagtatttct
    17821 aaaataagtt taataaattc tataataatt tattttttgc cttaaaattg ccttaaaatc
    17881 caaacaattt taaaactaat gtactataaa aagctggtat aatttaaata tagtaaaaaa
    17941 taagatttat cttatctatt gggatttaat tatttaatca atatatttat accatttaat
    18001 ttaaataaaa agtctattaa ggagtgagct tatgagtaag ttaatttata tagcagatga
    18061 tgaagataat ataagaaatt tggtaaagac attcttaaaa aatgaaggtc atgatgttat
    18121 ggattttaaa acgggtgatg aacttttaga acaatttaat ataaaggagt gtgacttagt
    18181 aatactagat ataatgatgc ctggctcaag tggttttgaa gtatgtacaa aacttcgtga
    18241 gaaaagtaca gtcccaataa tcatgcttac tgcaagagat acagatatag attatattac
    18301 agggataacc ttaggtagtg atgattattt tacaaaacca tttagcccaa tgtctttggt
    18361 tatgagagta aaatctatat ttagaaggat agagtttgaa aagaaacaaa attatgataa
    18421 atatagtaac tcgatagata tggaattaaa atttggtgat gtaataataa ataaaaagaa
    18481 taaaatcgtt acaagtaaaa atgtaaatat agaccttaca ccaaatgaat ataacctatt
    18541 gacttatttg tttgaaaata tagatagagc agtttccaga gatgaattat taaacaaaat
    18601 atggggatac gatatagaag ttgagacaag ggctgctgat gatacagtga agagattacg
    18661 taaaaaaatt ttaaatacaa atattttaat agaaactgta tgggggtttg gatttaggtt
    18721 gaaggagaaa agttaagatg aagaatggaa atgacaagaa tagaattgga aagattaaat
    18781 ccaaatttaa attaaagttc tcaaagaaaa atataagcat aaaaactagg attttgttga
    18841 gtatactttg tttgataatt atagtattta tgataatatt agtatctttt aatgtatttc
    18901 ttgatacata tataaaaaca actgcgaatg aagaattgac aaagtctaca gaaatagtag
    18961 aacatatgga tagtaatttt agacctatta agccaccaca agatgatgga aagcttcctc
    19021 ccaaagtatt atctaatttt atgagaaatg tacaagataa agttaggatg gcagaaacac
    19081 aatcagatgc tgatgctatg gtagttgatt ctaagtataa cctgatattt ccaacaagag
    19141 aggatgattt cttaaaaaat gttgatgaga tggagctgat tagggagtgt attcaaaatg
    19201 aaaaattaga tttaaattca gatgaaaata cacggatatc taccagaaat aaggattatt
    19261 atatttcaac tgtaaaaatt actagtatat atggtgaaca agacaagtat cttatacttt
    19321 ttatagacat atcaaaaact ctaaatctag cacaaaagat aaatattgta ttaatatctg
    19381 taatgtgttt tgctggaata ttagcaatat ttacagctgt gattttatct gagaaaattg
    19441 ctaaaccgat aaaagagttg tgtgagtttg caaaaaaaat gggtcaagga gatttcaaaa
    19501 gaacctactt tgacttttca gataaagaat tagtagagct ctcaactgtt atgaataaga
    19561 gtgctgagta tctggataag tatgataatg aacaaaaaat attttttcaa aatgcatctc
    19621 atgaattaag gacaccactt atgtctatta aaggttatgc agaagctata aaatataatg
    19681 ttatagatag taaacatgca agtgatataa ttcttgaaga aagtgatagg ttaagtgata
    19741 tggttgaaga tttattatac atttctaaaa tagataatat aactaaagat tttgaacttg
    19801 tagaatgtga tttaagagaa gtactttcaa attgtggagc taggcaaaat gtaagagcta
    19861 taaataaggg gataaaattt atttatgaat ttgatgaaga aatggtttta tttgaatgtg
    19921 atgaaaaaaa catttccaaa gcatttatga atcttataga aaatgctttg agatacgcta
    19981 agagtgaaat aaaaatagtg tgtaagtata atcaaaaaaa tatagttgtg ataatagaag
    20041 atgatggaat tggaatcaag aaagaagatt tacctcatgt ttttgaaaga ttctataagg
    20101 gagtaggagg aaatcatgga attggattat caatagttaa atctattgta aataagcatg
    20161 gtgggcgtat atacgtagaa aatggcaaaa aaggagctaa atttactata ttatttaaat
    20221 tgtaaaaaaa ttagagaaaa tatagagatg tttgaagttg ttttttatat atatctgttg
    20281 tatactgttg aaaaaagaac aatattaagc tgacatatat tacgatagtt gacatttaaa
    20341 gtaaatgctt aaatatagat acgaaaggaa aagtaaaatc tgaagtgtat ttaggtttaa
    20401 gtaagcttct tattttataa aaaatatgta tgaaagaaca gctgattttt aatattacaa
    20461 atttagtaac ggttgtattt gaagcttttg tcatccatat gtttttatca gactttttag
    20521 gtcagaaaga agggtatata aaagttgtaa gatatgctaa actgggtttt ataatatgtt
    20581 taggattctg taatttaata actttaaacc ctaaaatcac aatgccttta attttcatcc
    20641 ttattttttc aacatcattt ttatataaag gaaatttaaa gacacgattg tttactactg
    20701 ttttattaag tatattcttt atactgtcag aaattgtagt tacaagtatt tttgttttat
    20761 ttgtaaaaga aggctttgaa ataatgcttg aaaataatag tataagagta ttggcgacaa
    20821 ttttatctaa aattgtcttt ttgttgactt gtaaaattat ttgtctattt aaaaaggatg
    20881 tacatttaga tatgcccata aagtattggc tccctttatt tttaatacct atatttagtt
    20941 tatttctgtc tgtttctatc tttgatgtaa gtaaattttt tagtcttgaa agtttaaaat
    21001 ttctaagctt aatatctagt gttggtattt tatatattaa ttttattgtc ttttatttat
    21061 ttaaatttat tatagataaa actaaactat ctatgaaata tgaactactt gaaaaagaaa
    21121 taattcataa ggaagaatta agacttagta atgagtgtta taaaattatt gttgaacaga
    21181 ctgattctgt cgttttcgaa tggaatatca aagaaaataa atcatttgta tcgcaggctt
    21241 ggactgaaaa atttggatat aacaatgcat gtaagaatat ttttaaagaa attaaagata
    21301 aagacttagt tcattctgaa gataaagcta tatttgaagg ttttcttgaa agtattaaaa
    21361 aaaagaatat gcacaatcaa gcagtatatc gtttaaaaaa atctaatggt gaatatattt
    21421 ggtgtagaac atcaattaca agcatttata atgatgaaaa tgaactttta agagttgtcg
    21481 gagtaattgt agatgtagat agtgatataa aaaaatatga agagttaaga actagagcag
    21541 aaagtgactc attgaccaat atatacaata aaggtacatt tgaaaaatta gtggaagaaa
    21601 ctatagttat gaatacaggt gataaaaaag atgcattatt cattattgat ttggatgatt
    21661 ttaaagaaat aaatgataat tttggtcatc catttggtga ttttgtacta aaaacatttg
    21721 ctgataagat acaaactagt tttggtagta aagacttagt cggaagaatt ggtggagatg
    21781 aatttgttgt atatatgcaa gattatgtta cagaagtaaa tttgcataaa aaagctaaag
    21841 aattaaatag agtactttcg gataattaca ctgatttgag ttttagtttt gatgcttctg
    21901 tcagtatagg tattgcaagg tatcctcaag atggaacttc attttttgaa ttgtttaaaa
    21961 atgcagatag agcactttat agcataaaag catcaggtaa aaattcatat tgtttatttg
    22021 aagaagaact atatgtacag tgaatttgaa tttagatttt atgtgagagt aagatttata
    22081 tatacttgtg gctgtctgat ttataaaata tgttactttg tatattttta tatgtttcag
    22141 taaggttaat taacatgagc aaaggtgtaa gtaaatttat attagtttaa gtttacttac
    22201 acctttataa aaatacaaat aatagattca tttacattct taaatgatta aagctcttta
    22261 ccttctaaac atgcataaca tatcgttata attccagtaa ataagactaa aatgcccatt
    22321 actaagatta caatttcatc atctattact ccaaatgttt ttaaagtaac ttatttcgct
    22381 ttgtatcata ataatttgtc tctttttaca ttttaacttc tgctgagatt tgagttagat
    22441 attcattaga atctcgcaca cttatatcat atagaagata ttcttcataa acaaaatccc
    22501 caatacgtaa attattctga ttaaaaaaat ttaataactt ttcataagcc ttgtaaatag
    22561 tttcataact ccctttatga taagcagtta cataaagtcc ctttggtttg attgatacag
    22621 gatatttctt gtactcttta ttaacttttg taaataaata tgaatatgat tcaaagtctt
    22681 tattaattat atcttcacct ttaatgattg agccaatcgt accataatca ctcaattcat
    22741 agttgtccat aaagttaata cattcatata aaaaattttc ttcctcatct cctaaaaact
    22801 gttctttata tgtaacaggt gttttgacca agtactcttc ttcatgttct tttaaagtaa
    22861 tagtattcgc atctatatta catgcacttt tagtaaatga aatagtagat tccattagag
    22921 cttgaatatt atttagtttt tcaatttcat ttttaatatc aatggttttc ttttctaaaa
    22981 gctcaattag taaattaggt gttcttttgt ctatataagc tttaatttct tttaaaggca
    23041 tttttacttc cctaagtgaa gaaattatac caaaaatgct aagttgatgg tatgagtagt
    23101 atctatatcc attttctttc tttaattctg gtgagaaaag acctatatca tcataatgga
    23161 aaagtgtttt tttattgatt ccacaaatct ttgcaaattc tccagttgta aaataatttt
    23221 ttgaaacttg actcataatt ataattcctc cttgactatc ctgttacagt atagtttatc
    23281 atagtatttt gtaaaggagt gtgattatat gaaaaaatta attcattttt taaaaccata
    23341 tagagtttta attgttgtag ttttgatatt tacgttttta caaacacttg gaactttgta
    23401 tataccaaca cttacagcaa atatagtaaa taatggtgta gtaaagggag atatagatta
    23461 tattgtaaaa acaggtttaa tgatgatgat agtagctggt ataacagctt tatcagctgt
    23521 gttagtttgt aaagtatcag caaatctttc atctggattt tgtagagata ttagagaagc
    23581 agtatttata aaatcacaag atttatcaat aaatgatttt aataatatag gtacagcatc
    23641 aatgattact aggagtacta gtgatattac tttaataggt cagtctgtgt ttatgtttat
    23701 tcaattagta ttaccagcac caattataac tgtttctggt ctattcttag catattctat
    23761 agataaagca atgacaatta ttattgttgt agtaatgttt ttattcatgc tttcagcatt
    23821 tttagttggt aaaaagctta taaagttgtt taaaatgatg caaataaaga tggataatat
    23881 gaatagggtg ttacgtgagg tagtaactgg agtaagagtt ataagagctt ttaataggag
    23941 tcgttttgaa aaaaagagat ttgatagaac tgcaatagat tattctgaaa cagcaatttc
    24001 aataaataaa atatttgcag tacttatgcc tattgtaatg ttaataatga atttaggtat
    24061 agtaagtatt atttggtttg gtgggatgag agtcagtaat ggaaatatgg aaataggtca
    24121 tataatggca cttgttgaat attgtatctt aattttattc tatttaatca tgggagtaat
    24181 ggtatttatg tacataccta gagcaggtgc atgtgcagat agagtaaatc agatattaga
    24241 tatagaacct gaaattgtag atggaaatgg tcataaagat actgtctcag agagaggaca
    24301 tttagtattt aaaaatgtaa ccttttcata tgcacaatca gaagaacctg tgttaaataa
    24361 tataacattt gaagcaaaat ctggagaagt aactgcaatt ataggaagca ctggctcagg
    24421 caaatctact attgcaaata taataccacg tttttttgaa attcaatctg gagaaatatc
    24481 tataaatggt caggatatta agaagattcc tcaaaaagaa cttagagata agattggatt
    24541 tgtaccacaa aaagcttttt tatttagtgg aacaatagaa gaaaatataa ggtatggaaa
    24601 agaagatgca agtattgaag aagtaaagca tgctgcaagt atagctcaag ctgatgaatt
    24661 tatttatgat atggaagaca agtatgactc atttgtagca caaggtggaa ataatttgtc
    24721 aggtggtcaa aaacagagaa tatccattgc aagagcgtta gttagaaagc ctgaagtata
    24781 tgtctttgat gatagttttt ctgcattaga ttttaaaaca gataaaagac ttagaaaagc
    24841 gttgaaaaat gaaatcaaag attcatcagc tataattata gcacaacgta taagtacaat
    24901 catggatgct aatcagatta tagttttaaa tgatggaaaa attgtaggta ttggaaaaca
    24961 taaagattta cttgaaaatt gtgaagttta taagcaaatt gcggattcac aacttagtaa
    25021 agaagaactt gcataaaatg aagaattaat ctgatatttg gaggtgtatg atatgagtga
    25081 aaaaagaata gatgaacaag atatagaagt acttagtttt gaagatggca tgtcagcaga
    25141 aaaagctaag gatgcaaaaa aaactactaa gagattatta aaatatatgg caaaacaaaa
    25201 gtttaaaata ttaattattt ttatttcagt attgataagt tcagcgctta cagttttagc
    25261 acctatggtt atgggaaaag ctattgacca actatttaat ggaataaaaa ctgcagtcca
    25321 aacaggtaca aaattcagtg tgaattttag tactatggga gggatagtat caatacttct
    25381 agggttgtac ttaattagtg cagtatttat atatattcaa cagtatatta tgtcaggagt
    25441 tgcacaaaat ctagttctta gcatgagaaa agatttaagt gataaactca ataaacttcc
    25501 tcttaagtac tatgattctc ataaaaaggg ggaaacactt agtatagtaa caaatgattt
    25561 agaaaaagta gcagatagtt tacaagaagg attaatgcaa cttattacag cagtagttac
    25621 agtagttggt tctattgtaa tgatgataag tataagtgta ccacttacaa tagtatcagc
    25681 tataacatta cttgtttcat tgggtattac tgttgtaatt gcaagaaaat cacaagaaag
    25741 attctctgaa aatcaaaagg cactaggaga gttaaatagc aatatagaag agatatttac
    25801 tggtcaaata gtggttaaag catttagtaa agaaaaggat actataagaa actttaaaat
    25861 attaaatcaa aatctttata atgcaagtag aaaagcacag ttttcgtcat atgcaatatc
    25921 tccaattatt agatttataa acctaattgg ctatgttatt atagcagttg taggtgggat
    25981 atttgcatca actggagcaa tgactcttgg tagtatacaa gcgtttattc aatatgtaaa
    26041 tcaagcatca gagcctacta cagaaatatc ttatattgta aatatgcttc aagcagcaat
    26101 agcatctgca gagagagttt ttacagttat ggacgaggtg gaagagataa aggatgaaga
    26161 atcttcaaag gttattagca tgcctaaagg taaagtacaa tttgagcatg ttaaatttgg
    26221 atatagtgat gattttattc ttatgaaaga tattaatatc aatctaaatg caggagataa
    26281 gattgcaatt gttggaccta caggagctgg aaagacaact cttgtaaatt tacttatgag
    26341 attttatgag atacaaggtg gaagaattac tattgatggt gttaatataa aagatttaaa
    26401 gcgtggagaa cttagaacta tgtttggtat ggttcttcaa gatacatggc tatttaatgg
    26461 aagtataaaa gaaaatattg catatagtaa gtcagatgcc acaatggatg aaattgtaag
    26521 agcagcaaaa tcagcaagag tagaccattt tataaggact ttaccacaag ggtatgacac
    26581 tatattgact gaggatgctt ctaatctatc tcaaggtcaa aagcaacttc taacaattgc
    26641 cagggcaata ctttcagacc catcagtatt gattcttgat gaagcaacat ctagtgtaga
    26701 tactagaaca gaggtagaaa ttcaaaaggc aatgaataac ttgatgaagg gaagaactag
    26761 ttttgttatt gcacatagat tatcaactat tcgagatgct gatttaatat tagtaatgaa
    26821 agaaggaact attattgaac aaggaagcca taaggaactt attgaaaaga aaggattcta
    26881 tgaagaactt tataacagtc aatttacaag tgaatatgat gaagatgttg tatgattatc
    26941 aagttttagg caactaaatg attgataaat attaagttaa atatagtaac atgtaaggtt
    27001 atatggaata agagtatttc tctatttcat ataacctttt ttatttatca aaataagata
    27061 aaatttcctt tctaaattag attgaagaat gtatttatca atataaaagt aaaataatca
    27121 ttattattag tgaagtaaat attgtttgcc acatatatgc cataaagatg cacttatttt
    27181 acggagattt aacaaagtag tgtaaagtat actctaaata taaaataaat caaatagagt
    27241 taaataaatt gagaggtgat ataaatagtg aataaaaaat tgaactatag atttgaaatg
    27301 aagcacaaaa taactgaagc agatgtgtta gctttaaaat caagactcta tccaataatg
    27361 aagaaagatg aaaatgcatc taaagatgga aaatatctta ttaggagttt atattttgat
    27421 actcctgaag ataaagcact tttggataaa ttaaatggcg ttgcaataag agaaaagttt
    27481 aggataagat tttataataa tgactgctct tatataaggt tagagaaaaa aatcaaacat
    27541 tacaacatga catcaaagct atcaactaat ttaaccaaaa aagaagtaat aaatatacta
    27601 aataatgata ttgaatttct aaaagagtcg acaaattgtt tattaagaga attttatttg
    27661 aaattaaaat gtgaaagatt agaggcaaaa agcatagttg attacaatag agaagctttt
    27721 atttatccag ttggaaatgt aagagttaca atcgatagtg atattaaaac ttctgtaaat
    27781 tcggtagatt tatttaataa agatttgcca actgtttcgg taattgatga gaatatgact
    27841 gtattggagg ttaaatatga tgaatttata ccagatttta taaaggattt aattcaaatt
    27901 aataagacta cctctacagc agtttcaaag tatgcttcaa gtagattata tatttaagaa
    27961 taaaggctat gatttatata aagatataca taaataagat taaaaaacaa ataagttaaa
    28021 aataaaaaat aaataagtta aaaataggaa ggatgatttt aattatgaca tttaatgata
    28081 tttttaaatc aagttttata gaaaacgtat caggtttttc atttgtggac agtgctttag
    28141 cactaggttc agctttttta gtaggtttgt ttatatatat ggtctataaa aagacttata
    28201 tgggaattat gtattctcga ccattcaatg tgtcgcttgt agcacttaca atgcttacaa
    28261 cttttgtaat attggcagtt acttcaaatg tagttttatc cttaggtatg gttggtgctt
    28321 tatctatagt aagatttaga acagcaatta aagacccaat ggatttagta tttctatttt
    28381 ggtcattggg ttcaggtata gttttaggag caggtttgat tcccttagct gtcatgggtt
    28441 caataattat gggattgatt ctaatattct tttcaaataa aacaatatct gaaactccat
    28501 atatattgat ggtaaattgt aataatgaag attcagaaga tatagcaact gataaaatta
    28561 aaaaagtatt tactaaatat caaataaaat caaaaagtgt tacaccagaa aaaggaatag
    28621 aattagtgtt tgaagtaaga atgaaagatg gagaaacaag tcttataaat gacttgagtc
    28681 aagtagatgg agttactaat gcagttcttg taagttataa tggtgactat gtagcataga
    28741 gaggagtaat cttttatgaa agataaaaaa tttacccttc ttatctcgat tatgattata
    28801 tttttatgtg ctgtagttgg agtttatagt acatctagca acaaaagtgt tgatttatat
    28861 agtgatgtat atattgaaaa atattttaac agagacaagg ttatggaagt taatatagag
    28921 atagatgaaa gtgacttgaa ggatatgaat gaaaatgcta taaaagaaga atttaaggtt
    28981 gcaaaagtaa ctgtagatgg agatacatat ggaaacgtag gtataagaac taaaggaaat
    29041 tcaagcctta tatctgtagc aaatagtgat agtgatagat acagctataa gattaatttt
    29101 gataagtata atactagtca aagtatggaa gggcttactc aattaaatct taataactgt
    29161 tactctgacc catcttatat gagagagttt ttaacatata gtatttgcga ggaaatggga
    29221 ttagcgactc cagaatttgc atatgctaaa gtctctataa atggcgaata tcatggtttg
    29281 tatttggcag tagaaggatt aaaagagtct tatcttgaaa ataattttgg taatgtaact
    29341 ggagacttat ataagtcaga tgaaggaagc tcgttgcaat ataaaggaga tgacccagaa
    29401 agttactcaa acttaatcgt tgaaagtgat aaaaagacag ctgattggtc taaaattaca
    29461 aaactattaa aatctttgga tacaggtgaa gatattgaaa aatatcttga tgtagattct
    29521 gtccttaaaa atatagcaat aaatacagct ttattaaacc ttgatagcta tcaagggagt
    29581 tttgcccata actattattt atatgagcaa gatggagtat tttctatgtt accatgggat
    29641 tttaatatgt catttggtgg atttagtggt tttggtggag gtagtcaatc tatagcaatt
    29701 gatgaaccta cgacaggtaa tttagaagac agacctctca tatcctcgtt attaaaaaat
    29761 gagacataca aaacaaaata ccataaatat ctggaagaga tagtaacaaa atacctagat
    29821 tcagactatt tagagaatat gacaacaaaa ttgcatgaca tgatagcatc atatgtaaaa
    29881 gaagacccaa cagcatttta tacttatgaa gaatttgaaa aaaatataac atcttcaatt
    29941 gaagattcta gtgataataa gggatttggt aataaagggt ttgacaacaa taactctaat
    30001 aacagtgatt ctaataataa ttctaatagt gaaaataagc actctggaaa tcaaagtgat
    30061 gaaaaagaag ttaatgctga attaacatca agcgtagtca aagctaatac agataatgaa
    30121 aataaaaata aaactacaaa tgatagtgaa agtaagaata atacagataa agataaaagt
    30181 ggaaatgata ataatcaaaa gctagaaggt cctatgggta aaggaggtaa gtcaatacca
    30241 ggggttttgg aagttgcaga agatatgagt aaaactataa aatctcaatt aagtggagaa
    30301 acttcttcga caaagcaaaa ctctggtgat gaaagttcaa gtggaattaa aggtagtgaa
    30361 aagtttgatg aggatatgag tggtatgcca gaaccaccgg agggaatgga tggtaaaatg
    30421 ccaccaggaa tgggtaatat ggataaggga gatatgaatg gtaaaaatgg caatatgaat
    30481 atggatagaa atcaagataa tccaagagaa gctggaggtt ttggcaatag aggaggaggc
    30541 tctgtgagta aaacaacaac atacttcaaa ttaattttag gtggagcttc aatgataata
    30601 atgtcgatta tgttagttgg tgtatcaagg gtaaagagaa gaagatttat aaagtcaaaa
    30661 taagattaaa attgaatata aataatttta atactgttaa gtctaaatat ttacttagca
    30721 gtatttttta gaaaataatg tatttggtta ctaatataag gtaataaatt gataaaaatt
    30781 aaatacagca tattaataat acataataaa gtaataaaaa aactgtttaa gtataataac
    30841 ttatatttag acagtttttt tcatttataa ataatataaa tgaaattgaa aacatttgaa
    30901 ggatagaaat tggttggata aatgtataaa ttacttcacc aaaaaataat gacaaaaatt
    30961 gtaactaagt tgtaataaaa tggtagttat ttagcataaa ataatgtatc atagaagtat
    31021 attataaaat taataaaata agatttttgt aagaaaactg ctggcttttg atatttagag
    31081 tgagtagtta aattatgttt aggaggggta gaatttgttg caaaaagtat tatggaaatt
    31141 tttaaagcta gtagtcggtt tatttatatg ttcagttggt atagtattga cgataaattg
    31201 taaccttgga ttatctccct gggatgtatt tcatcaagga ctttcaaatc atataggaat
    31261 aactatagga actgcttcta taattgtagg ctctatagta gttattgctg atgtcgttct
    31321 tggagaaaat gtaggatggg gaactgtttt taacatgcta ctaattggat tttttatgga
    31381 tttactttta tatagtaatt taattccaga ggctgataat ttatttgtag gaataattat
    31441 gttgatatta ggattggttc ttttgtctgt tggaatggta ttttatatgg gaagtggttt
    31501 aggaagtgga cctagagatg gtttgatggt tgcaattcaa aagaaaacag gaaaatcact
    31561 taaattaata agaggtacta tagaagttgg agcattaata gtaggatttt tattaggtgg
    31621 aaaagttggt ataggaacta taataagtgc atttggattg gggtatttca cacaaatggt
    31681 atttggctta tttaaattag attgtagtaa gattaaacat agatttatag tagatgatat
    31741 aaaatttatc aaagtgtata tgagtggtga gaaaaaagct gctgttcaaa atatagttaa
    31801 gtaatttaag aataaattca acgaaatgtt aagtatttta aattaacatt ttgtttagat
    31861 agataaattg aatattaaaa gaatattaaa atatgaggat tgctagaaca ctataaaata
    31921 tagatttcta gtaatttttt atttgttcaa tattttttta gtactagaag tcttattctc
    31981 tatttaatga atgaattaat ttataattag agatactaaa ctttatagat attaatataa
    32041 acacctttaa actgtgtatt ttccaaagcc tttaaaatgc ttgtatttat tctaaataaa
    32101 aaaataaaaa aatgtcaaaa aaactcttgt attatatcca aattttatat ataattacct
    32161 atgttgttta gaaattttaa actcaatgtt tagtaaacaa aatgtttagt aaaataaaac
    32221 agaaactagg aggtgcaaca tggatatagg tgaaaagata aaaagattaa gaacagaaaa
    32281 acaactgacc caggaagagt tagctaatag atgtgaattg tcaaagggat ttatttctca
    32341 attagaaaat aacttaacat caccatccat agctaccctt atagatatac ttgaaatact
    32401 aggtacaaat ttaagggaat tttttaatga aatagatgat gaaagaatca gttttacaaa
    32461 agaagatatg tttgaaactg aagatgaaga tttaaaatat aaattaaagt ggttaattcc
    32521 aaattcacaa aaaaatgaaa tggagccaat aataataaca ttgtatccag gaggacagta
    32581 taaagaagaa aagccacatg aaggtgaaga atttggatat gtattagcag gttcaatata
    32641 tgtccatata ggcgaaaaga aaaataaagt aaaaaaagga gagagttttt actttagacc
    32701 gaaagcaaat cactatatat caaacgaggg caaaactaca gcaaaagtga tttgggtaag
    32761 tacgccacca tcattttaga atagaggtgt ttaataattg gtagaaaata taatagaatt
    32821 aagggatata tctaaacatt atgaagaact tactgtttta gataatttca atttagatat
    32881 aaagaaaaat gagtttctaa cattgcttgg accaagtgga tgtggaaaaa ctacaacatt
    32941 aaaaataata gcaggatttg agtatgctga tgatggtaaa gttttatttg aaggtaagga
    33001 gataaataat ttgccaccat atgaaagaca agtaaacaca gtatttcaaa aatatgcttt
    33061 atttccacac atggatgttt atgaaaatgt agcttttgga ttaaaaatta aaaagactcc
    33121 aaaagatgta atagatgcta aagtaaaaga ggttttgaaa cttgttgcac tagaaggttt
    33181 tgaaagacga caagttgaat cattgagtgg aggacaacaa caaagaattg caatagcaag
    33241 agctctagtc aatgaaccaa aggtattatt actagatgaa ccacttggag cacttgattt
    33301 aaagttaaga caagagatgc aaatagaatt aaagagaatc caaaaaaaat taggaataac
    33361 atttgttttt gtaactcatg accaagaaga ggctcttact atgtcagata ctattgttgt
    33421 aatgtataag ggcaaaattc aacaaatggg aacaccacaa gatatataca atgaacctaa
    33481 aaattcattt gtagctaagt ttataggtga aagtaacata tttgatggaa ttatgataga
    33541 agattataaa gttaatttct gtaatagaga ttttgagtgt gttgataaag gattcgaaaa
    33601 aaacgaaaat atagaagtag taataagacc agaagatata aaaatggtaa agccagaaga
    33661 aggaatgtta aaggggaaag ttacatctac agtgtttaaa ggagtgcatt acgagataga
    33721 attgaatgaa aatggaagat tgtggatact tcataatact aaaaatgctg aggttgggac
    33781 tgaactaggc atggatatat atccagaaga tatccatata atgagaaaag agaataacta
    33841 agatgaaaag aaaatctttt ttagcatatc catatgtagt ttggagtgcg atatttgtaa
    33901 taattccttt aatattagta gtatttttta gttttacaaa agaatcaggt ggaggttatg
    33961 cctttacact tgagaattat aaagaagtaa ttgaccctat atatatgaaa gtttttgggc
    34021 gttctattct tttagcagga ggagctacat taatatgcct tatagttggt tatccagtgg
    34081 catatataat ttcaaaggct cgtgtaagta gaagaggttc attaatatta ttgtttattc
    34141 ttcctatgtg gatgaacttt cttttaagaa catatgcatg ggttgctata ttaggaaaaa
    34201 atggactttt aaatacattt ttaggttggt ttggaataca accattagca attttgtata
    34261 ctaattttgc tatactttta ggtatggtgt ataacttttt accatttatg gttcttccaa
    34321 tatatacagc actatcaaag atggataatg atttgataaa cgctgctcat gacttgggtg
    34381 caaataatat gacagttttt agaaaaatta tatttccttt gagtttgcca ggtgtaatgt
    34441 ctggaataac tatggtattt atgccagcag tcactacttt tgcaatatca agactgttag
    34501 gtggaggtaa aataatgctg gttggagatt tgattgaaca acagtttaca gttgttggag
    34561 attggaactt tggttcagct atatcgatat ttatgatgat agtaatatta atatctatgt
    34621 ctataatgtc aaaatttgga gatgaatctg acaaagaagg cggtgggtta ctattttaaa
    34681 attaaagaaa ataacttcta atatatattt agcattagta ttcttatttt tgtatgcacc
    34741 catatttgct ttggtactat tttctttcaa tgattcaaaa tcaatggcaa gatggaatgg
    34801 atttacatgg aagtggtatg gtcaattact tcaaaatgag agtataatga gtgctttata
    34861 ttatactatt gtaatagcta tattagcgtc tgtaatatct acaatagtag gaactataag
    34921 tgctatagga atacataaga tgagaggtaa gagtaagaaa ttaatactaa atgtaaacta
    34981 tcttcctatt ttaaatacag agatagttac agcagtagct cttatgagtc tgtttgtatt
    35041 tgtaaaaatg gaatttggat ttacaacaat gctattggca catataatgt tttgtttgcc
    35101 atacgttata ctttcagttt tgccaaaaat gaagcaatta cctgataata tagaagatgc
    35161 agctatggac ttgggagcaa cacctatata cgctcttaga aaagtaattt taccacaaat
    35221 aaaaccaggt atagtttctg gatttttaat tgcatttact atgtcaatag atgactttat
    35281 aataagtttc tttaatgctg gaaatggtgt aagcaatctt tctatagaaa tctatggaat
    35341 ggctagaaga ggtataaaac ctgaaataaa tgcattatca acaataatgt ttgcagtggt
    35401 tctaggttta cttttactag ctaataaaaa agaatctata gtaaggggga ttaaataatg
    35461 attaagttta aaaaagcaat atcccttata gctgtaggta tgatgacagt tactttattt
    35521 acaggatgta ataaagcaac tgattctaca aaagttttaa atgtatataa tgttggagat
    35581 tatatagatg agtctcttat agataagttt gaaaaagaaa caggaataga tgttcaatat
    35641 tcaacttatg atactaatga aatgatgtat caaaaagtaa agagtggtag tacacactat
    35701 gatttagtat ttccttcaga ctatatggta gagaaaatga aaaatgaagg tcttttggaa
    35761 aaattagatt ttaagaatat acctaatatg aaatatttag ataagagttt tttaaatcct
    35821 gtatacgaca aaactaatga atatagtgtt gcatatatgt ggggaactct tggaatattg
    35881 tacaataaga aagaagttaa agaccctatg gatagctgga atatactttg gaatccaaag
    35941 tataagggaa atataatgat gtttgactct gttagagata ctatagggat aactcttaaa
    36001 aaattaggat atagcatgaa tagtgtaaat ccaaaagaaa taaatgaagc taaaaatctt
    36061 ttaatgaaac aaaaggattt agtattggct tatgtaaatg atgaaggtaa ggatagattg
    36121 cttggtggag aagtggcaat gggtatgctg tattctggag atgcagttac actaatggag
    36181 caaaatcctg accttgatta tgctatacct aaagagggaa ctaataaatg ggtagatgct
    36241 atgtgtgtac ctacaacagc acaaaataag aaagaagctg agctgtttat aaacttttta
    36301 ttagacccag agaatgcaaa agtaaatgct gagtacattg ggtattcaac acctaataca
    36361 ggagcactaa aattattaga cccagaaata actcagaatc ctgttgcata tccatctaaa
    36421 gaagtacttg ataaatgtga aacttttgaa gatattggtg aaaatataaa attatatgac
    36481 aaggcttgga tagagttaaa atcaaaatag ggtcttgttg ttttaagtaa atttacttaa
    36541 taaatactta ataaaactgt tcttttttag aaaatttatt ttctaattat tgaacagttt
    36601 tattttttgt ttaagttata ttcatatgca atttaaatag tttattaata aatgaaaact
    36661 tatttgtata atgactttaa taataattag aaaaaatggg caacttaata gaataattgg
    36721 aggtgtaaat ttataaaaaa tgaataggat aaataaaaaa atagatttat taatattggc
    36781 tttgctcgtt tttatatttt taattgttgg aatagtaata ctatcgatta ggacagaaaa
    36841 taaattgaat gtgttcataa tgttagcaat aatttttttt ataataatgt taacttattt
    36901 atcaaattca gtagtggggt tgataacaag ttcaataatt atatttatgt atacatccta
    36961 tattttatat aacaatatta ctcacaatat ggatgttgaa tttatatcat atatgtggat
    37021 aatagcaaca ccagtatctt caattataat gggtaatctg aacaaaagca taaatgaatt
    37081 gcaaaataca aataaaaaac tatctgaaca gtataaggaa ttagtgacta ttgatagtga
    37141 aactggactt agaaatttaa agatttttta taatgatgta aatatggaga taagtaaatc
    37201 tattagacat aatactgatt tttctcttat gatagtaaaa ttaccatact acggaaacct
    37261 acagactata tttggtgaaa acaaaactaa taaaatagta aaatatattg gttcaaatat
    37321 tatagaatgt acaagaaatg aagatataat ttatagttta caaaaagata tgatagggat
    37381 actaatgcca aatacatctt tggaaggttc aaaagttgtt aaagacagaa taaagaaaag
    37441 gataaaagaa ttaaatttag atttaaacaa taggggaaaa tatgtaaata tagatgtcaa
    37501 aattgcattt ttacaatata agagtagttt tggagatagt ataaatttta agaatatagt
    37561 tgaagaggaa cttcaatatg atgtttaaaa tatttaataa aagtctatta aaattagtag
    37621 ttgtattatc aatagtactg acaatatcaa attttagctt atcttcatat gcatcagaaa
    37681 ttacttccag cacagataag gtattaatca tatatgattc taagaaagaa acagcttata
    37741 atagagatat tttaaatatt atgaggactc tattgggaag atttagttca gatatagagc
    37801 tattaaaatt gagtaactat gatggtgaga taaataaaaa ttattacagt catatattta
    37861 ttttaggaat caatgaaaac tcatataata atgataaaaa cactaaaaac ttgattagtt
    37921 ccttaaattc atataaagga actatatgtt ggttaggata tggtatagaa aatcttttgg
    37981 aacataaaaa atacaattta gactatgtag gaaaaacaaa caatatagtt agtgtaaatt
    38041 atagaggtaa atcatataac ttggatgaac attatgtttt taacattgta gaatcaaaag
    38101 atacaagtaa taaagtaata ggaagtatta atgatacctt aaataagtat ccatatataa
    38161 taaatgataa aaatcttttt tatgtatcaa aattagattt agatggagtt ttattttata
    38221 tattttgcga ttcacttaat gatattttta atattaagac gtttgataaa ggacgtatat
    38281 ttgtaagaat agaagatgta catgctttta gagaaccaaa aaatcttgta gagatagcgg
    38341 attatttaag tagtaagaat ataccattta cgattgcatt aataccagca tatgtaaatc
    38401 ctaaaaatca taaggtaata actttatcag aaagccctga aattgtcaaa gcaataaaat
    38461 atatgcaaga taaaggtgga actgtgatat tgcatggata tactcatcaa tacaagaaag
    38521 aagaagtttc tggagaaggg tatgaatttt gggatggtaa aaaagatgaa cccttaaaag
    38581 aaaatatgaa gatatttgtc aaagatagag ttttgaatgg tcttagagta tgtatagaga
    38641 atggaattta tcctcttgca tttgaagcgc cacattatgc aatggaatca gagggatata
    38701 aagaattaaa aaaatatttt tctacttata tagggcaaca tcaaaataat gataaaaaat
    38761 ttagcacaaa tacatatcct tatattatta gggatacaga ggagtttaat atatttatac
    38821 ccgaaaattt aggatatata gacccagaag ataagtttac ttttcaaaat ataaaagaaa
    38881 atttagataa attatccatt gtaagaggtt ttagtggagg gttcttcttt cattcatatt
    38941 taaacataga gtatctaaaa aacacaatag aatatttaga aaaacagaat atagaattta
    39001 tgaatttaag agattttaat aattgggtaa aagttgatga aatacaaata agaaataatg
    39061 gagatgaaat tatagtcaac tatgataagg acttagatga actaactaaa agtgatacta
    39121 gatttaaatc catatccaat attagtaaag ttttaatatt catagtatct ataagtgttt
    39181 taatatttgt gattatattt atatatttta agagaataga taaaaagaaa tttttaaaat
    39241 aaaggatttt atattagaat caatatttta aaatatttta ggagaaattt atgagagatt
    39301 taaatgtatc agagtatttg ttcgtattta gtttgtttag tatatggtct ttattgctta
    39361 taaatattat tttagctatg ggtggatata tattttattt taaaaacttt gataaagaaa
    39421 taaaagaaat tgatgaatat cctatgatat caatacttgt tcctgctcat aatgaagcta
    39481 aagtgatagg tagaactgtg gagtctttgc tattactcaa ttatcctaag agtaagatgg
    39541 aacttattgt tataaatgac aattcttctg ataatagtaa agaaatttta gaaaatataa
    39601 aggataggta caacaattat aatttcacta taataaatac agatagttta acaggtggaa
    39661 aaggaaagtc taatgcatta aatattggat atacgatttc aaaaggagat tttatagctg
    39721 tttatgatgc agataacaca ccagataaaa atgcacttag atatctagta caaactatag
    39781 taatgaatga tgaattaggt gctgttattg ggaaatttag gactcgaaat aaaaataaaa
    39841 acctattaac caaatttata aatatagaaa cattaagctt tcaatggatg tcacaagctg
    39901 gtagatggca actttttaat ctatgtacaa taccaggaac taactttata ttgaggagaa
    39961 gtatcataga agaaattgga ggatgggata gtaaagcaat tgcagaagat acagaaataa
    40021 gttttaggat atataaattg ggatacaaga taaagcttgt accacaatct ataacatggg
    40081 aacaagagcc agaaactgtt aaggtgtgga taaagcaacg tactagatgg gcaaaaggga
    40141 atatatatgt attaatgaaa tatataaaaa atatatttaa acagggaaga aataagattg
    40201 tgtttgatat agcttacttt ttttctgtat attttctatt tttaacatct gtaattatat
    40261 ccgatatttt atttgtttta agtatatcta aactagtaga aatttctatt ccaattaact
    40321 tttttctaat atggatacta tcttatcttt tatttattat agaagtgagt ataagcctta
    40381 ctatagaaaa aggtgaagca acaattgaaa atatattcat agtggcaata atgtatttta
    40441 catactctca actatggctg tttgtagcta taaaaggaat gatagagtat ctaaaagata
    40501 taatttttaa aagagaggtt aaatggtata aaacagaaag attttgattc atgtacagga
    40561 ggaattaaca tgaaaaaatt tattatatca attatatctt tagtattgtt tttttcaaat
    40621 atatcactta tatacaaagt aaatgctgat gagactaaag ttaaaaatta taagtttgaa
    40681 agagatataa ctattgatgg tgttatagga agtaatagta ctttttttga agtaaataaa
    40741 aattgggata ttgaagaagt tttattgcat cttaatttta gtaagagcca aatattaaat
    40801 ggagatgttt caagtttaac tgtattgata aataatgtac caataaaatc tattaaatta
    40861 aatgctaaga caaattataa aaatacatta gaagtattag ttccaaaaga ttatataatt
    40921 caaggatata atgaaataaa aataaaaaca tacaaaacaa tatctgataa aatttgccaa
    40981 gatgattcca atactgggaa ctggatggtt attcacaaag aatcatatat atcaattaga
    41041 tataagcaga aaaaggtgga aaactcaata aatgaatatc cgtatccata tgcagaaatt
    41101 gaaaataatc ataaattaga tacaactata gtagtaccag ataatatgac tagaggagag
    41161 actacagcag tgtttaattt ggcatcagca tttggaaaaa taacaaaaaa tgatgattta
    41221 aagttagatg ttaaattata ttcagaaatg aaaaattggt cagatgataa tattatatat
    41281 attggtaaac ctgaaaatac agcagaagaa attttggata ttttaagtat aaaggaacaa
    41341 accctattat cttcaaactg tataatcaag caagtagatt caccatacaa taagaataag
    41401 aagatgatgg tggtaattgg tagtaatgaa gatgatttaa taaaggcatc aaatttatta
    41461 atagaaaata gactttctaa ccaagtttta tcatcatcag tacttgtaaa caaagagact
    41521 aatataaaaa ttaataggga acaaaaatta aatttaggtc atttaacatt aaaagattta
    41581 ggatattctg actttttgtt ggaaggagca tttaatcaac aagctttgtt tgatgtcaaa
    41641 ataccaacgg gtaaggtatt agatgatggt tcaaagatta tcttaaattt aagatattct
    41701 gacaatttag attttgaaaa atctttagtt acagtgtcta taaatgatgt tattgtggga
    41761 agtaaaaaat tggataggtc acattctaat aatgataagt tagaattaaa aatacctaaa
    41821 gatatagata ataaaaacta ttatcaagtt aaattgacat ttaatttgag tataaaaaat
    41881 tcgaattgtg ttactagaga gagtaataat ccttgggcat atgtatcaaa taattcttat
    41941 ttggcgttat ctacgaaaga aaatgaaacc ttatcttttg aaaattatcc gtatccattt
    42001 gttagagatg atgaatttaa tgatttaact gtgataatgc cagattattc agggtcacaa
    42061 gctatgacct ggatgtttag attaggtgtt actttaggtg cgaatataaa ttcacataat
    42121 ggaaatataa atgtaattag aggaaaagaa tttagtgaca agtataagga tactaatatt
    42181 gtagtttttg gagtgccaca taataattct gttataaaga tgttaaataa taatttaaat
    42241 ataaagttcg ataaaaatta ctccaatttt atatcaaatg ataagataag ctttattgat
    42301 gattatggaa aaaatatttc tactattcaa ttaataaaat caccatataa taatcaaaaa
    42361 aatatcatgg taattagttc aatgaatgaa aaaaacttat atttaggaat ggattatttg
    42421 ttgaataaaa gtaaagttaa tgatttaaaa ggagatacat tgataattga tgaatacgga
    42481 gaggtagaag atttagctta taatttaaaa tctaagaaag aagtaaaaga ttcaagttgg
    42541 aatatgagta taaataagac aactaaagta tttttaatga tttcttttat tactataatt
    42601 atagtcatga tattatcaat gctatatata aaaaaatata aaagaagata atatgataaa
    42661 tttattattt taaaagaggt atataatttg aggaaatata tgaatgaatt taaattaaaa
    42721 agaagtattt taatctcatt aataatctta atttttatat ttatagttta ctttgtaagt
    42781 attgagttaa aagataggag tctagtaaat aatcaatata aaggtaagat taaatcggcc
    42841 aatttatctg tagattatga aataaatcaa gttatgaagg atatagataa attgggattg
    42901 aatacagtaa atgtacctat aattataaat gtagagtcca ttaattctga tattatgtca
    42961 atagataata atagtaaaga aaaggcaatt aagttaataa aaaaattaaa taaaaaaggt
    43021 atttcaacaa tattagaggc atatccatgg attgaaaatg gaaaattgta tgagactgac
    43081 tggaacccta taaataaaaa aagatttttt tatacttggc aaaatgccat attaaatgaa
    43141 cttataattg atgtagcaaa tccactggat gtaaatgttt taaatattgg ttctaatttt
    43201 gtacatttgg aagaatatca acaaaattgg ggtgaaataa tagattttgt acaatccaaa
    43261 tttgacggtc ttgtaacgta cagaactaat tggtggtata caaaaaaaga tgatttaagt
    43321 agtaagttgt tttatgaaca aaagctgaac aataattttt ttgataagtt agattttata
    43381 tctatagcag catattttga gttaagtaat aaacctgtta atacagtgga tgaattaatt
    43441 tctgccttac actcatctac tgtaaacaat agaggacaaa atataaaaca agaaatatat
    43501 aacctttata aagctcatag aaaacctata ttttttggag aattaggttt ttcaaataga
    43561 gaaagtgcaa gttctcagcc gtggaatcat actccttcaa aagctgtaaa tggcgaagaa
    43621 caagcaaggt gttttgaggc atataagaaa gtttttgaaa atgaagactg gataaatggt
    43681 ttttctgtgt tttgtgtagg taaaatagat gacgaaaaaa atttttaccc atcaaaagag
    43741 agtataaaag ttattaagtc ttggtatgaa taattttgaa agtgtagaat ttatatagat
    43801 taaatagatg attaggagag atataaatga atgacatcaa ggttatgact gtatttggaa
    43861 ctagacctga agctatcaaa gtagcacctt taataaagga acttgaaaaa agagagaata
    43921 taaaaagtat tgtttgcgtt acagctcaac atagagaaat gcttgaccaa gttatagaaa
    43981 cctttaatat aaatgtagac tatgatttgg atataatgga aaaaggacaa agcctgaatg
    44041 atataacatg taagatttta aataaacttc ccttgatttt aaacaaggaa aatccaaata
    44101 taatattggt acatggagat acaaccacaa ctctagctac aagtttgact gcattttata
    44161 ataaaactct tgttggtcat atagaagctg ggcttagaac ctatgataaa tattctcctt
    44221 ttccagagga gctaaataga caacttacag gtattattgc tgatatgcac tttgctccta
    44281 ctaatttggc tagaaaaaac ttgatttctg aaggaaaacc taataataat atatttgtaa
    44341 ctggtaatac tgctattgat gctttaaaga tgacaataaa agaaaactat aatcatccta
    44401 taattgatga gattggtaac gataggatga ttttgttaac ctctcacaga agagaaaatt
    44461 tgggtaaacc tatgaaaaat atattcagag ctataaagcg aatagtagat gactttgaag
    44521 atgtacagat agtatatccc atacatttaa atcctaaaat acgaactata gctgatgaga
    44581 tatttggaaa atttcctgaa aaaattcata ttatagagcc tttagatgta gctgattttc
    44641 ataacttttt aaataaatct tatatgataa tgactgatag tggaggaata caggaagaag
    44701 ctccatcatt aggtaagcca gttcttgtgt tgcgtgataa aacagaaaga acagaaggaa
    44761 ttgaagcaaa gacacttaaa ttagtaggta ctaatgaaga tagaatatat aattcagtga
    44821 gcgatttatt aataaataaa gataactatg ttcagatgag taaagcatct aatccatatg
    44881 gagatggaaa tgcaagcaaa tatatagtgg atataataat taaaaaattt aattgcaaat
    44941 atttaaatta gataaggcct aaaacattaa ctaattgata taagatttat gataatatta
    45001 agtaatacaa tttttaaggg ggagtaatat ggctagaaaa ttaataaaaa atttgggtaa
    45061 aagtaaaagt gtaaagagag tgaaactttt atttaagaag atttttatta ctgtattcat
    45121 agtagcaagt atagttgcta tttttaatat aacgaaatat tttgaggaat tatacaaagt
    45181 aagggattta aaaagtacta aaattgaata ctatatggat gtggctgatg aagcaggaga
    45241 tggaaaggtc caattaagtt ggaaggcctt acttgctata gacatggtaa tacatgatga
    45301 agatttaagt aatataaaaa agaaagacac attggatata ggggaaaagt ttatagtaga
    45361 agataaaaat ggtaaaggcg aaaaggtgta taaggtaaaa aagtttaata aggtattaag
    45421 cgaattgaaa tttgactctt ctcaaaaaag tagagcaaga aaatacatga aagatttaga
    45481 atacacatac cttggaaata aacaattaga tagtagtgat gaaaaaatta aatttataaa
    45541 gaagttagaa gactcagcta taagagaata tattgattat ggaatattgc cctctataac
    45601 aattggacaa gctatattag aatctggttg gggaaattct aaacttacaa aacagagtaa
    45661 taatttattt ggtataaaag cagataaagc atggaaagga aaaagtgtag aaatttcaac
    45721 ttcagagcat tataatgaaa aaattgtagc tagttttagg tcgtataatt cattacaaga
    45781 ttctgtcaaa gaccacagtt tatttttaat taataataaa agatatagaa aacatgggtt
    45841 gtttgaggca aaagattata ttagtcaagc tcaagcatta gaaaatgcag gatatagtac
    45901 agcagaagat aaaaaaggaa atcgtatata tgcagagcta ttaatagatg ttattaggag
    45961 ttataatttg caattgatag ataataaagt tgagacaaaa taattgttaa ctttatatga
    46021 ggagataaca agataagatt tttttctaca aaaagaatag aaaaattgta aaaaaaacta
    46081 aaaaaatgta ttgacttgtt atttaaaagg tgatattatt attactgtac tcgaaagaga
    46141 acaaaa
//
LOCUS       DAMKNB010000026        46025 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.027, whole genome shotgun sequence.
ACCESSION   DAMKNB010000026 DAMKNB010000000
VERSION     DAMKNB010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 46025)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 46025)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..46025
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.027"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            95..937
                     /locus_tag="PC494_001607"
     CDS             95..937
                     /locus_tag="PC494_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3100 domain-containing protein"
                     /protein_id="HDF3912111.1"
                     /translation="MKEKAGIRNAIIAAFIITILAELIGPISFKVMGINVTLLSILWA
                     IFIGMAVSPHLLGRVIPALKKFIGDNEINVSPYLLSLTLYPLGIMFGINAGPKVGILL
                     QAGPALLLQEFGHMGTMLIALPVGVALGLGRSALGGTFSLCRDTALGIIGDKYGLNSP
                     EGIGTLGTYISGSIFGTLLFSFLAPVGVLLGFHPYALAMASGMGSGSMMGAATASLMN
                     TVPQMSEQILAYSATSGLITAVTGIYIELFLSLPVANYYYSKVAPVIERFRGRKTRRT
                     SNKL"
     gene            952..1416
                     /locus_tag="PC494_001608"
     CDS             952..1416
                     /locus_tag="PC494_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3912112.1"
                     /translation="MEKTFKTIMEQIKIVLFIYIIICFGQMIALKTQAQDLLIGSVSG
                     FLLVIIAIIIKNFVKKPNLPGFAWATLVAFVLSLPISPVGDIIATNVGKINFMSTVTP
                     LLAFAGISVGNQLDILKTLSWKLVVISFIVMTSTYFGSAFISQTVLRLNGML"
     gene            1403..2575
                     /locus_tag="PC494_001609"
     CDS             1403..2575
                     /locus_tag="PC494_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HDF3912113.1"
                     /translation="MECFKEVVNMNELKAKIKEEIKLLSEEKKTSFEKVSDYLFSNPE
                     LAFEEYKSQKALCDLLEENEFNVTKGVGGLETSFEAVYSNGTNGKTVAFLAEYDALPG
                     MGHACGHNIIGTSSVGAGIILKEIMKKHNIEGTVKVFGTPAEERVGGKITMIKEGVFN
                     NVDAALILHPSDASMPDDISFAQVNLKFDFTGKASHAAAFPWEGKSALSGVIALFNSV
                     NSMRLHLKDYARVHGIITDGGSIHNIIPEKSTAIFNVRALSIEYLNEICEMLKNCAKG
                     AAISTGTNVEIVQLDEIYKEIKNDSELVNIVRQNFEVLGEDYVERDLSQGIGSTDTGN
                     LTHEIPAIQAYIKLKENTATHTDEFAVAAGGEEGRVALIKAIKVLAMCGVDILYSK"
     gene            2619..3554
                     /locus_tag="PC494_001610"
     CDS             2619..3554
                     /locus_tag="PC494_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1177 domain-containing protein"
                     /protein_id="HDF3912114.1"
                     /translation="MILKQVIEVYDILDKANANGEEVKTYLQGYGEVDVTVKELSSSK
                     GSTDLVKLTIPGKNGKLKGGDAPTLGILGRLGGIGARPEVIGFVSDGDGALVAIAVAA
                     KLLDMQRKGDILDGDVVISTHICPDAPTKEHYPTPFMDSPIDMMTMNENEVDSSCDAI
                     LSIDTTKGNRVINTRGFAISPTVKEGYILKTSDNLLDIMQTVTGKSPFVFPLSIQDIT
                     PYGNNLYHLNSILQPAVATDAPIVGVAITTEMPVAGCATGATNFSDLDSAGRFAIEVA
                     KLFGRNKCDFYDKEEWEMLIKRYGKLNRFQTFGIQ"
     gene            complement(3925..4650)
                     /locus_tag="PC494_001611"
     CDS             complement(3925..4650)
                     /locus_tag="PC494_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HDF3912115.1"
                     /translation="MLESKIRTPEEIKRYMLDLKKWLAQERSKPVEEMSDFFSKRIDI
                     YDNVHLANWTEEYAHIADYFDTPLSSLLDIGCGTGLELASIYRKFPNVQITGIDLSKE
                     MMSKLKEKYSDKNIDLILADYFEYPFEQEKYDAALSFETLHHFKYQKKQKIYKKLFQT
                     IKPGGYYVECDYIACCLEEETICLEQYEFKCKENHVPDDVFVHIDIPLTIEHQIHLMK
                     NAGFRAVYVLHENNGTMIIKAEK"
     gene            complement(4668..5234)
                     /locus_tag="PC494_001612"
     CDS             complement(4668..5234)
                     /locus_tag="PC494_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDF3912116.1"
                     /translation="MPPKPIITKQDIINAAIQLVRENGISSVNARNLAKTLNCSTKPL
                     FRIYTNMDEIKEDIKIELDNYYNSFMESKINDENRLLSQGLAYIEFAQNEKMIFNTLF
                     MNMTMKGSSLQDIIHAKWNRITIENAKKVTGLSIEKSEMLFINFWLYSHGVATQIISN
                     GIDIPLDMVQQLLENAFERFSLDITKTE"
     gene            complement(6145..6543)
                     /locus_tag="PC494_001613"
     CDS             complement(6145..6543)
                     /locus_tag="PC494_001613"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HDF3912117.1"
                     /translation="MKWKELYNKARGKLNPRTISPFIDAGGVAAAILTDSGNVYTGVC
                     IDTACTLGMCAERNAIANMITNGESKITKLVCVMSNGSVGSPCGACREYLMQLDKDSA
                     CIEILVNVETEKTVKLSELLPDWWGSDRFI"
     gene            complement(6842..9535)
                     /locus_tag="PC494_001614"
     CDS             complement(6842..9535)
                     /locus_tag="PC494_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglycosylase domain-containing protein"
                     /protein_id="HDF3912118.1"
                     /translation="MNNDNDKNGNKIRRKKVSSSGNTNKPINRTSANKTRSTKNKKKS
                     KKSDKFKKLRVFGIVFLVLLVVGTAGTAGLVFASLRDVTPVTEAVLDKQTNQTTTIKY
                     ANGKTLSTAPSVNKKTPVPLDKISPYLQHAVIAIEDERFYEHKGVDIKGLFRSVLKTL
                     TGTKQGGSTIPMQVSKMLLTTEQQTIPRKIKDIYYAHEMSKTVSKDKILETYLNNFFV
                     GRGLAGAEAGARGYFDKSAADLTLAESALLAGSTKNPSRFSAYKTSKLEGNETKEDLE
                     NKLLFFVNTTDDDLDDPTQVDFDMIEKIKSWELISNDTYRQLKAGTLVVRKAVSNPEA
                     KKRQEIVLKKMLELKYIKQSEYDEAIKAKIEIKLPQSSDKVSSSVEDLIESEVINALM
                     EQGHTNDEAQNLFYNGGLIVNTTIDPKMQDALEEEFDRNSNFPGHMVGPDGVSQPQAA
                     MVILDYKNGEIRALAGGRNISGRKTLNRATNPHQPGSSIKPLAIYTPAIDTLKITQAT
                     ALSDSRGGYKFEENNKWNPRTTTASHGSMSLRKAFAKSSNTIAVKTAEMLGDSYDECV
                     DIMMDYLKNFGITTLKNNHSGSSEASDRKFPSLTLGGMANGITPLQMAAAYGTLANHG
                     IYVEPSIFTTITTFDGQLLVKNAPEEHKVVEPEVAYVVTDMLESVITEGTGGVAALPK
                     GMPVAGKTGTTNSAYDAWFVGYTPYYVGATYIGDDAGRKDDSGNTIKRREVPHGSTST
                     AKLWEKIMEKIHANLTVTEFEVPKNVYFTKINLEDGGKQSSGSKAAFIEGTAPTKVSS
                     QPSSEDTKKPDNNQPEENNNNNNNTGDNGGGSTPPDNGGNNGGGSTTPPDNGGNNGGG
                     SATPPDNGGNNGGGSTTPPDNGGNNGGGSTTPPDGSGTPAT"
     gene            9749..10447
                     /gene="yunB"
                     /locus_tag="PC494_001615"
     CDS             9749..10447
                     /gene="yunB"
                     /locus_tag="PC494_001615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation protein YunB"
                     /protein_id="HDF3912119.1"
                     /translation="MNRIVDRKTKNEFRKIIAIFLVILFLSVFIGSFIYIDKTLRPTI
                     TVLAETKALELANRSINKAVAEMVEGKINYEDLMDIQLDNNGKITMIQANTIMMNEIA
                     SAIALEIQDELKKDKTASSYIPIGTALGSPILAKYGPKLEVSIEPIGTVSVNFKTEFE
                     SSGINQTRHRIYLEAQTQVKVVIPLITSTKQIKAQIPICETIIVGDVPESYVNIPEKN
                     LGNVLPNTGKNTNK"
     gene            complement(10659..11666)
                     /locus_tag="PC494_001616"
     CDS             complement(10659..11666)
                     /locus_tag="PC494_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase S55"
                     /protein_id="HDF3912120.1"
                     /translation="MQLKNFHFKNNTLSKKTNLAKSKFTIVLTFLFLLYFFSNNLIYA
                     QNLQKNEPEYLIPIGNVLQIDAELKNIIVRNPGEASPFRLGDAIVKVNNAEVDGYSDF
                     ANTLNALPEEKQVSILLNRGGQLITMKTTKHILEKISFNNLLSGFATLTYINPDTSEF
                     GAVGHPISVGNARKIPIKTGSISTTKHLNIEKSYKGSVGCINAKRENIIGSFTENTDF
                     GIRGQINNFDISKLKKYKVASLDEVKLGKAQIILQDNFNKCKKYNIEIIDIENQKHPE
                     SKSFKIKITDKKLLAQTGGIVQGMSGTPIVQDNKIIGAVSHAIENDPAVGYGVFIKWM
                     L"
     gene            11894..12778
                     /locus_tag="PC494_001617"
     CDS             11894..12778
                     /locus_tag="PC494_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HDF3912121.1"
                     /translation="MKKYRLLVTCIIAMGIIIIGTSNPVSNFYKTTNLISSGNITNEK
                     ADKDENSNKNNKDKNEDKSNSKSNKDKSSEDKSSDNKNEIQKNKKLLICIDPGHQGKG
                     DSNLEPVAPGSSSKKARVSSGTEGIATKKPEYVLNLEASLVLKSILESKGYNVIMTRE
                     THDVNISNSERAILANDKKADMVVRIHADSLNNSSKTGASILIPEKDGKYTAPIYEES
                     NKCAEFIKQNMEQSGIQINGIVQRGDLTGFNWSKVPAVLVEMGFMSNYNEDQMMSNPD
                     YQRKMMQCIADGLDAYFK"
     gene            12980..14530
                     /locus_tag="PC494_001618"
     CDS             12980..14530
                     /locus_tag="PC494_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018592108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HDF3912122.1"
                     /translation="MLVVENVSHGFGARTILENVSFRLRKGEHIALVGANGEGKSSFL
                     NIITKKLMPDAGNIKWSSRATVGYLDQHTVLSKGKTIREVLREAFKHMFDLEQEMIAM
                     YDKMGEASDDEMSKLLEETAEIQTILENSGFYMIDAKIQEVANGLGLGEIGLDKDVTD
                     LSGGQRTKVLLTKLLLENPTILILDEPTNYLDEEHITWLTKYLQEYENSFVLVSHDIE
                     FINNTCNVIYHMENGELNRYKGNYDEFVRLNDIKKRQEEQAYDKQVEERKRLEDFVAR
                     NKARVATRGMANSRQKQLDKMEILERPKEKIKPTFAFKDARAASKIIFETENLVLGYD
                     EALTKPLNFHLERGKKIALKGMNGIGKSTLLKTLLGIIKPFEGNVKLGDYLEVGYFEQ
                     ESSRENSNTPMDEVWSEFPGLTNFEVRQALAKCGLTNEHITSQMRVLSGGEAAKVRLC
                     KVMLKNINFLVLDEPTNHLDVEAKDELKKAIKEFKGTVLLVCHEPEFYSEIVDDVWNI
                     EDFTTKIV"
     gene            14559..15206
                     /locus_tag="PC494_001619"
     CDS             14559..15206
                     /locus_tag="PC494_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HDF3912123.1"
                     /translation="MKKFLNVLFSICISIVIIVGVINFTVGFKQLYYFDIDYLNISEL
                     SGLSKDDIKLNYDYLIDYNLNKNVSEFKLPTLKSSPQGKIHFEEVRNIFQNINKLAKL
                     LLVVSLVGIILSVKNKNIKILKTTSITLIIMPLLLTVPILLNFEKSFIIFHKLLFRND
                     YWIFNPDLDPVINILPEEFFFHSGMMILILILLVSIVLFVMYKLCKSLSIKIFQC"
     gene            complement(15348..15608)
                     /locus_tag="PC494_001620"
     CDS             complement(15348..15608)
                     /locus_tag="PC494_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich small domain-containing protein"
                     /protein_id="HDF3912124.1"
                     /translation="MGENYKFFNHKDCEFFPCHKTNKPEEFNCLFCYCPLYALGENCG
                     GNFKYTDKGIKDCSSCILPHKKDNYNYIMSKFQDLVKITSKK"
     gene            15825..17108
                     /gene="hflX"
                     /locus_tag="PC494_001621"
     CDS             15825..17108
                     /gene="hflX"
                     /locus_tag="PC494_001621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HDF3912125.1"
                     /translation="MKEIQEKALLVGLNLTTIVKKNDDIDTNESMEELKELTKAAGAE
                     VVGSLIQNKHSVDAAYYIGKGKVEEIRAYSDSLDATLVIFNDELSGAQIRNIENVVGR
                     KVIDRTTLILDIFAQRALSKEGKLQVELAQLKYRLPRLYGMGGEMSRTGAGIGTRGPG
                     EQKLEIDKRHILNKAADIRRELKEVKKNRETQRVKRLKSNIPIVALVGYTNAGKSTLL
                     NELIKTHKDYEQEKEVFVKDMLFATLDVTLRKALLPNKKEFLVVDTVGFVSKLPHDLV
                     EAFKATLEEVQYADLILHVIDATNTSYELQKSTTEGVLKELGVNDKKHILVYNKVDKL
                     ELDIYPKSQEDIVYISAKQGINMDKLLNMIEIALMENTYSVRLMLPYERGDIFSRIKD
                     KYNVENFEYGESGITLDVDLDEEDFNIYREYILEK"
     gene            17116..17793
                     /locus_tag="PC494_001622"
     CDS             17116..17793
                     /locus_tag="PC494_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HEAT repeat domain-containing protein"
                     /protein_id="HDF3912126.1"
                     /translation="MDINWENIDNLEDYFITYLLYKESKTVSQISKIRNISSTEASEQ
                     LIQAKLKIKEMQKDDFEASKDILDKFLELDKIKRLDFMDSLDDEKMVYFKRKVFKRIL
                     VEKNAEDLIVLIWATGELKDDRFLKLLHQLTNHRHSDIRRITYSAIRKIESPSSREVL
                     QKGLYDKNAQTRQYCAKALSKLGDENSLKILQQLKDKNKNFEKEYVLRAYDEAIKSLE
                     NAKNLKK"
     gene            17879..18322
                     /locus_tag="PC494_001623"
     CDS             17879..18322
                     /locus_tag="PC494_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HDF3912127.1"
                     /translation="MIVRRCAGGVVFYANKVLIVKNDRGEWTLPKGKILGGGLPYESA
                     VQRVKVETGIDAKMIDVAGDTMYEFFSRSRQQEVCNAIMWYVMEACNTDCVLAPEFQE
                     GGFYKVKDALEMLSHHKEQALVEVSYKKFKELKKLVSEGDDVPAN"
     gene            18627..19271
                     /locus_tag="PC494_001624"
     CDS             18627..19271
                     /locus_tag="PC494_001624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HDF3912128.1"
                     /translation="MSNYRTLHEFGTDEITIEKSVFIGYAKPIKSEEEALEFINEIKK
                     KHKDATHNVWAYTVGKNMNIQRYSDDGEPQGTAGIPTLEVIKKEDLRDVAVVVTRYFG
                     GTKLGAGGLVRAYTKGAKLGLEAGKIIYKVMYQEVKVKIDYTQLGKVQNELMNLGYFI
                     KDTVYEDNVEIVVYSRLEDVEKLSEKMIDITSGTGKIVLGEEFYLSEQNGEILI"
     gene            complement(19357..19734)
                     /locus_tag="PC494_001625"
     CDS             complement(19357..19734)
                     /locus_tag="PC494_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HDF3912129.1"
                     /translation="MLFALIGFFAGIIGGMGMGGGTILIPALVLLAGIDTKIAQSVNL
                     LSSIPMTLIALAIHIKNKNVIFKLVIPIAVFGVLGAVFGSLLANYLSSDILKKIFGIF
                     LLLVGLFEVKKGFCAKSDKKPLN"
     gene            complement(19734..20120)
                     /locus_tag="PC494_001626"
     CDS             complement(19734..20120)
                     /locus_tag="PC494_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HDF3912130.1"
                     /translation="MKKTDDLKKKYFDFNLKNTIIGVFTGFINGVFGSGGGTLLVPIL
                     NDIVKVEEHKSHATALSIIIFLTTASSVLYVSKGTYDVNLTIKVAVGSILGGIIGAKL
                     LNKVTGKFLRISFGIIMIIAALRMVF"
     gene            20299..21054
                     /gene="nadE"
                     /locus_tag="PC494_001627"
     CDS             20299..21054
                     /gene="nadE"
                     /locus_tag="PC494_001627"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(+) synthase"
                     /protein_id="HDF3912131.1"
                     /translation="MSNIKIQIDKTVEWLINKVNEANAKGLIVGVSGGIDSAVVANLI
                     KKAFPENSMGVIMSIKSNPQDREDALKVIEGCDIEYLDLDLIEPQSAILDMVVGNLKD
                     KHLYREEYLKMTDANLRARVRMSTIYTIANNLGYLVVGTDNAAEIHTGYFTKFGDGGV
                     DILPIANLTKGEVYEWAKELGVHEDLINKAPSAGLWEGQTDEDEMGTTYNMIDAVLEG
                     RLDEVPKRDQEIIERLHRLSEHKRKTPAQPPKF"
     gene            21137..21856
                     /locus_tag="PC494_001628"
     CDS             21137..21856
                     /locus_tag="PC494_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HDF3912132.1"
                     /translation="MGRIGNIINRKGKQDAQRAKIFTKHARAIAVAAKEGGADPEYNA
                     ALKTAIEKAKADNMPNDNIDRAIAKGAGAGAGEDYETIVYEGYGPGGVAVIVETLTDN
                     KNRTAGNVRYYFDKNGGNLGTSGCVSFMFDKKGQILVGLGDGVSEEELMDVALEAGAE
                     DFITEEDGYEIITTPEDFSSVRDELKAKGYEFISADVKMIPQTTTVLTEESHLKMMNK
                     LVDMLEEDDDVQDIYHNWEVE"
     gene            complement(22023..23027)
                     /locus_tag="PC494_001629"
     CDS             complement(22023..23027)
                     /locus_tag="PC494_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HDF3912133.1"
                     /translation="MATIKDIAKDCGLSSATVSYVLSGKGNERRIPLHTQELILNSAD
                     KLGYKRSTPIKHNNIKIAFYWQDEGFELASTNILQAINHIISLEHLNINIIIRPYKVG
                     HLCDDEYFFANNYYDGIVLTGINADDIEYLVKNKPKIPVVVVNREIPGFSSVSIDNEE
                     TGRIAALHAIQNGKNDIAVVFNPTSFTCMTLRGKSFLKTCKEHGIHLSDSIYYCSNKI
                     DSGYDIAQKMLAKNSLKKVIFCNHDVVALGMMNAFHESGIVIGEDIQIFAASNGPSRL
                     MARSIPPLTVIDLKMEETAERSLRMIIDTVTGRINGIQQQVIYPSIIYRQSSPAQNLL
                     "
     gene            23293..24189
                     /locus_tag="PC494_001630"
     CDS             23293..24189
                     /locus_tag="PC494_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA lyase"
                     /protein_id="HDF3912134.1"
                     /translation="MSKVNIFEVGPRDGFQNLKEFLETDKKLKIIDGLIASGIKQLEI
                     SSFVSPKAIPQMKDAKEVATYCVEKYPDVKLYALVPNLYGAKVAWECGIRDISYVISL
                     SETHNKKNINRTHEESIDELKKIMNTYPDMNICIGMATVFGCPFEGLPKIEDAIRFAK
                     CLWENGIREINLADTIGIADPKQVRETISALVEALPECRWQVHIHDTRNMGMVNTLVA
                     IESGITTVQSTLGGLGGCPFAPGASGNTATEDLVYMLERMGYDTGVDFVKLLELSKYQ
                     KSFVNGVYSGHHVNIKSDSCNC"
     gene            24326..25588
                     /locus_tag="PC494_001631"
     CDS             24326..25588
                     /locus_tag="PC494_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3912135.1"
                     /translation="MDIIALLLFLGVIIIAFVRKNNAGILALAIGVIAVRIFGMDDKE
                     LYGAISNSMFTTLVGITLLFAIVNSTGALKLVAEKIVAASGKRVWLIPIAVFIAGFVV
                     AGVGPGAIPALAIIPAMAVPVAITVGYNPVMLALIGECGLMAGRMTPITPEGQIITTV
                     AEGVGIENVMPTILACQTLSTIVFSIVLFIIFKGYKLKKPINVIDSKQIEKFNIKQII
                     SLISIVVMIAFIIIFDMNVGLAAFAVSAVLIFFNIADEGECIKSIPWSTIVMVLGVGA
                     MMTIVDAAGGIDLMSNALSSLMNSKTATPIMSISAGLMSMVSSALAVVYPTMMPMCVD
                     IAKAVGGVDPLALIAAVGVGGSLAGVSPLSTGGALILAAMGSSKKDFNKEEQNKVFVQ
                     LFIMSAVGLLVIAVVSILSFNAITHLMN"
     gene            25664..26857
                     /locus_tag="PC494_001632"
     CDS             25664..26857
                     /locus_tag="PC494_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA transferase"
                     /protein_id="HDF3912136.1"
                     /translation="MKKGALSNIKVLDLTRVLAGPYCTMMLADFGADVIKIEMPRKGD
                     DTRGFGPFVNGESLYYANINRNKKGITLNLKSEEGKNIFLEMVKHADVVVENYRPGVM
                     EKLGLGYDELAKVNNQIIYGAVSGFGCYGPYSERPGYDIIAQAMGGLMSITGQEGGEP
                     TRVGNAMGDVLGGMNLTIGILTALNARKIIGKGQRVDVSLVDSVVSSLETGIQRYFDS
                     GQPELMGNRYASAYPYDSFKASDGSFVIGCGNDKLFEKLCKKVLFREDLLIDERFKTN
                     LNRCEHYKALKPEIEKWSVKHTIKEAVDLISEAGVPAAPIYNLDCVTTDKHIAKAREM
                     IVDISHPIIGNMKVNGNPVKLMTTKAKIDMPAPSLGESNEEIYNGWLGFDSDKIKDLK
                     ENGVI"
     gene            27486..28280
                     /locus_tag="PC494_001633"
     CDS             27486..28280
                     /locus_tag="PC494_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase/isomerase family protein"
                     /protein_id="HDF3912137.1"
                     /translation="MESVMENLNNLKVEVKDKVCVITINRPKALNALNSDTLRELSQV
                     IDVVSENEAILGVIITGEGKVFVAGADIRQMQNYKSEEGRKYAGYAQGIFDKIEALEK
                     TVIAAVNGYALGGGCELAMSCDIRIASEKAIFGQPEVNLGVIPCFGGTQRLSRLVGTG
                     IAKELIFTGRQVNAEEAKSIGLINKVVPSDLLLEESMKMMNQIVEKAPIAIRYAKVVI
                     NKGIDMDLKNALELEKDVAGLTFATRDKQEGMNAFIEKRKPVFENK"
     gene            28375..29715
                     /locus_tag="PC494_001634"
     CDS             28375..29715
                     /locus_tag="PC494_001634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntP family permease"
                     /protein_id="HDF3912138.1"
                     /translation="MNTGVIISLVGIIIALSLLVVMVMKGINIFIIAIVCSSLVAITG
                     SLNVYDALKVDYMTGFVGFLQANFFIFLTGTLMGKIMEITGGAKSIAKMIVRWIGKDK
                     ALLSIPIACGILAYGGVSVFVVSFAVFPIALEIFKEADLPRRFIPAALTFGCSTFAMV
                     APGAPQIQNIVPASTLGTDIMAGAVNGFISCAVMFIVGSTILYKMVSKEKANGGHFIA
                     HESDIFDEAEATNSKRENGPNGVIALIPLIVSILIINVKVNGKAIVPIEVGVFIGALL
                     VYLLLNKYQDNTKIVGHVGDACKTTVVAICNTCAVVAFGSVVKSAVGFDFIVNAMTNI
                     PGPPIAGAAVGTTVIAGICGSASGGLGIAAPLLGPVFLAKGVSAAALTRTMAISSAAL
                     DSLPHNGYIVTVTNGLCKETHKDAYMPIFWVTVLTPFIGTIVAVLLFTMFPGLP"
     gene            29852..31084
                     /locus_tag="PC494_001635"
     CDS             29852..31084
                     /locus_tag="PC494_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA transferase"
                     /protein_id="HDF3912139.1"
                     /translation="MLNKPLEGVKVIDLTYFVAGPGTSKILADWGADVIKVEPSFGDP
                     GRKTGATMTMPIDDYNNPFYSTYNSNKRGLSINLKSETGIEIMDKLLSEANVFVSSYR
                     TGALKRLGLDYESLSKKHPHLIWGQINGFGDFGPAKDNAGFDTVAFWARSGAMLDIAE
                     KDTSPINPPIAFGDATTSCSLSGGICAALYQQAKTGKGQKVMASLFGQAIWNASSLLA
                     STQFSDEYPKTRKNAISPVINSYRCKDGKWIFLSILEHERYFEALCRLFGREDLIKEE
                     KFASSVESKKNATELINILDGEFAKFTQNEMVEKLTAADIAHEKIQHVNDVVTDEQAI
                     ANNYIYEHTSKDGNKTMLASTPVKFGNIEVNMTCDAPLIGEHSDEILRELGYSDSDIE
                     TLIESGIVTMNKEACEIC"
     gene            31124..32266
                     /locus_tag="PC494_001636"
     CDS             31124..32266
                     /locus_tag="PC494_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA dehydrogenase family protein"
                     /protein_id="HDF3912140.1"
                     /translation="MDFRLTEAQLMLQRVAKEFAENEIAPIAAETDKTGIFPRELFSK
                     MAKIGFNGIGTPVEYSGSGGADIEKVIVVTEIAKKCAASAAILSIHTIYAQAILKFGT
                     EEQKKKYLPMMAEGGCVGAFALTEPNAGSDAARAATTAIIDEETDEYVLNGTKCFISG
                     GGQAESLIIFALTDPSKGIKGMSAIIVDKGTPGFSIGKIEEKMGIHGSETAELIFDNC
                     RVPKSNLLGKEGKGFNIAMTCLDGARIGVGAQAVGIAEGALEESIKYSKERVQFGKPI
                     SALQGIQWYIADMATMVESAKLLVYYAADLKARGEKHTKEAAMAKYNASRTAREVTNL
                     ALQIHGGYGYMKDYPLERMYRDAKITEIYEGTSEIHKVVISRAVLG"
     gene            32277..33071
                     /locus_tag="PC494_001637"
     CDS             32277..33071
                     /locus_tag="PC494_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009899720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit beta/FixA
                     family protein"
                     /protein_id="HDF3912141.1"
                     /translation="MNIVVCLKQVPDTNEVKINKETGTLIRDGVPSIINPDDRNALEE
                     ALKMKDELGAVIKVISMGPPQAKSALKEALAMGADEAYLISDRAFGGSDTWATSTIIA
                     AAIEKVGKYDVIFCGRQAIDGDTAQVGPEVAEFLGIPQVTYAKEVKVQDDKLLVTRYT
                     ETGDYLIEAKMPVLLTAIKELNNPRYPSVKGILEAYNNGDAKITVLTLADLDVDTTQI
                     GLKGSPTNVYKSFVPVKDKHNEIIEGINKKEKAEKLIEILFDLKLV"
     gene            33082..34104
                     /locus_tag="PC494_001638"
     CDS             33082..34104
                     /locus_tag="PC494_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit
                     alpha/FixB family protein"
                     /protein_id="HDF3912142.1"
                     /translation="MMRAKVNQGINLNDYNGVWVIGEQREGKINPVTIELIGEGRKLA
                     DQLGKELAVVIAGYEVEKEVKELLHYSVDKVYYINDPLLKDFTTDGYAISIANLIERK
                     KPEVVLVGATSIGRDIAPRIAGKVGTGLTADCTKLEIDSTDNKLLQTRPAFGGNLMAT
                     IVCPKNRPQMSTVRPGVMAKAVRNESETGILEVVTPELTEKMIRTRLVEILPQEKKSV
                     NLTDARIIVSGGRGLKRAEGFELIKELADKLGAEIGASRAAVDSGWIEHSHQVGQTGT
                     TVRPELYIACGISGAIQHLAGMSDSKYIVAINKDAKAPIFSICDYGIVGDLYEIIPEM
                     IESLNR"
     gene            34203..35579
                     /locus_tag="PC494_001639"
     CDS             34203..35579
                     /locus_tag="PC494_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-54-dependent Fis family transcriptional
                     regulator"
                     /protein_id="HDF3912143.1"
                     /translation="MKEQWYKDIFARVLSMTDDGFIVVNTSGVIIDINDKYCDFLGKE
                     RKDIIGQNIQSIIPNTKMLDVMKNKYCEEGAIHHYSGGNTKEKSVIVSRSYVENDNGE
                     VVAGVAQVKFRLQSFDVAKKLMSEYMELQYYKEQFKDNCGFDKLIGENRDFIELKKTG
                     VKASKTNFPVLLTGETGTGKEVFARAIHNNSSRSDKPMVSINCAAIPEELLESELFGY
                     DEGAFTGAKKGGKKGKFLVANNGTIFLDEIGDMPLTMQAKLLRVLQESEIEPVGGLKT
                     IKIDVRVISATRKNLSKMVEEGLFREDLYYRLNVINIHMMELKDRQDDILLLANYILN
                     KLNVEYKELKVLSDKVKNCFINYTWPGNIRELQNVIKSAYAVSDDMVIMMCDLPSKMD
                     NISRVAQCNVDSNCSIHEMVENYEKSLIIDVLRKYNWKCSKAAEVMGIHKSLLYKKIK
                     KYEIELNN"
     gene            complement(35911..36255)
                     /locus_tag="PC494_001640"
     CDS             complement(35911..36255)
                     /locus_tag="PC494_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3912144.1"
                     /translation="MDQIKRLHELQQKSYLTKEEFEELKNNTYIERFELRDECDNSYI
                     YTFYTNDKCNDIKFIKSQFIVTLIKIGFLCECGGVFRQKKIVDEYDYGYNAIYKCDSC
                     GKELDKEVENYD"
     gene            36743..37753
                     /locus_tag="PC494_001641"
     CDS             36743..37753
                     /locus_tag="PC494_001641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4116 domain-containing protein"
                     /protein_id="HDF3912145.1"
                     /translation="MHEDKNDIFESIDTEDFDNKTEEECLELVRKNGLNLIYIKNQTE
                     EICLEAVRQNCNAIKCVQNQTEKICIEAVKQDWRMLEFVEEPTEEICMLAINQDGTAL
                     KYIENQTEELCLRAVEKNGAALEYVKEQTEEICIEAVRNSEFGLARVKNQTEKICMEA
                     VKHCSYNLKWVENQTEEICMEAVRQNGLDLKFVKNQTETICLRAVRQNGMALEFVKEQ
                     TVGICLKAVRQYGMALKFVKEQTEEICTEAIKQDKRALSFVKGDKEKYKALYDNNEPF
                     AKRYVRNVIEKENRALIKKGEENAKIKIAGKLYDRGMSFEDISDIVEIEISKLKVSLG
                     VF"
     gene            37889..38377
                     /locus_tag="PC494_001642"
     CDS             37889..38377
                     /locus_tag="PC494_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HDF3912146.1"
                     /translation="MKITVLYQTRSGNTERVAKLIEEGAKKVDGVDVKLMRLDNIDLD
                     YLNESKAVIFGTPTYLANTTWEVKKWFDEDSKKVNLAGKLGAVFATCDYICGGPDVAI
                     LTIVGHLMVKGMLVYSGGGSLGKPFIHLGHVHSIEGPELQDEKAIIFGERIATKAKEL
                     FA"
     gene            38553..40481
                     /locus_tag="PC494_001643"
     CDS             38553..40481
                     /locus_tag="PC494_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HDF3912147.1"
                     /translation="MVWHIEYEIFSAIIVIFLMVYFFRSKFIPTLQNKIYCALLIFSF
                     LFIISNILGSFCLNNIDKIPIFITFLLNQIYLLLLPIPAALVSFYVMAIIYQDIRYMK
                     KRLLFLSIPLIICIILSITNPFTHILFGLSKETGYIRGCGYVATFASFFFYAIYSAFL
                     SFKYRKAMHESKIWAIRGFLIVSIVAIILQAIFLQYLLTGTACACSLLLTYLSMQNRG
                     LIIDDLTGVLNRQSFIQELDLNINTEQSGFIITIALDDFKFMNETFGTKNGDIALKEV
                     GKYLIQIHDVNHVYRIGGDIFSIVVNSQLGIEPDDIIRKIEERFKKPWLVEEISFNLA
                     TSIAVVYYPENAETTEDVIVAIDFSIHEAKRSESRRVVYADASISEKIKKKHVIKNCL
                     KEALKNDGFEVYYQPIFSNSRGRFTSAEALLRLEHKELGFIPPDEFIPIAEQTGLINS
                     IGLVVFEKVCRFIASDEFEDLKLDNIAVNLSVVQCMQKNLADDLLYLMNKYNVSPTKF
                     KLEITETVAMGSFNIIKETMERLIDLGVKFALDDFGIAYSGVTNMLSLPFSVIKLDKS
                     LIWSMNEDSRHKLTVETIIALINKLNMKAVAEGVETIKCAEDLIAMECEYLQGYYFSK
                     PVPEDVFKNLLKENTFTS"
     gene            40658..41068
                     /locus_tag="PC494_001644"
     CDS             40658..41068
                     /locus_tag="PC494_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HDF3912148.1"
                     /translation="MNKKKILVPIDGTERSMHSLEFIKGIFKKDEVEVEIMNVKELVF
                     IDGISLAEEIKNSENLGRRILDKAAEIMGEYDVKVHFTFGYPGDEIIRKAKEDNVDFI
                     VMTKSTKKGLTRMIGSVTASVVKQAKCIVMIVPE"
     gene            41090..41392
                     /locus_tag="PC494_001645"
     CDS             41090..41392
                     /locus_tag="PC494_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIBC"
                     /protein_id="HDF3912149.1"
                     /translation="MNKKIVAVCESERSLNSLKTAANDLGFDLVYEIQENDNIKNELS
                     IYDIEDASIVLFVTSDSIESIEKIDRFIDREFYEVDPKYIIEDAKSIVSEILIDLN"
     gene            complement(41609..42301)
                     /locus_tag="PC494_001646"
     CDS             complement(41609..42301)
                     /locus_tag="PC494_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FadR family transcriptional regulator"
                     /protein_id="HDF3912150.1"
                     /translation="MKSLNATEKIIDYIKLNILNGTFKINSKLPSERKIADLFNISRI
                     PVRNAINILCKEGILRAVPYSSPIVEGFKKVDLFDDGEIYKNHNIQEFYVESLRARQL
                     IESEATKLAILNATSKELQKIKYTYLKSIEELDKVSHGLIEECYDADLQFHKEIILAS
                     HNPIFIKYYELIPKTVSSNQYFGFKYRNSLKDMISHHNKIMIAFDSKDSYLGYTSMYN
                     HLEDVIQLFQHD"
     gene            complement(42327..43514)
                     /locus_tag="PC494_001647"
     CDS             complement(42327..43514)
                     /locus_tag="PC494_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDF3912151.1"
                     /translation="MKKISNQKLLLLSIVTFFWFSQYVYIPFQNPYLSACNVSTNMIG
                     IIIGAYGISQCLLRLPVGVFADSINKHKIFILSGIFFAGLASLIRVFSPGGNGFLIAN
                     ILSGISSSTWISYMVHYTNFFSTEHQQKATSTIILVNNLGMLIGFVMSTLFYEKLGMT
                     ALCIMSVLSSVIGTILALNIKNHNSKKIPEKISIKKYLSICKDKRLVFFSFMALIQQG
                     IQMSTTMSFTTQILKNLGSSSTLIGLSSIFYMVCAVASSGFASTKFCTKYGPKFWIPL
                     VFILVSAYCFLVPTIKNINIIFVLQVLPGISTGILLSYLTSESMKNVPKHQKSTAMGF
                     FQAIYAIGMSVFPMIVGKISEYTSIQYGYFILAIIAILASILSYTYYKKVDLTLNYDI
                     IQS"
     gene            43850..45649
                     /locus_tag="PC494_001648"
     CDS             43850..45649
                     /locus_tag="PC494_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HDF3912152.1"
                     /translation="MDYKNIAQEILLNVGGKENVNEVTHCMTRLRFKVKSASKVNKDK
                     LSKTEGVITVVESMGQIQVVIGNKVKKVYDEVIKIVPQSNNIGKKNESQEKQGIINSI
                     LSAVAGIFTPTIPAIAGVGMIKGILSVLAMYYMNKNGVDIKETQSYIILNAMADSIFY
                     FMPIILGYTAAKVFNANKIISMVLGATLCYPTFTALMAGEESVRFLGLAVTKATYTSS
                     VIPIIIAIWALSYVEKVLEKYIPEVIKIIMVPTLSLVVMLPATLFLFGPIGIYIGNVI
                     NFSYKYIYELSPALCGAFVGGLWCVLVIFGAHRALLPIGISDVAQTGRQNLLAFAGAA
                     NFSQAGAALGVFFKTKNQGLKTISMSATITALFGITEPAIYGANLRLKKPMVCAVICG
                     AFGGAIMGMGGAYGNAFANQGVLTIPVYAEAGALGFLSYLGGCAIAFFGSAISTYLVG
                     FEDLEESSNKENSSIKVETKDGVIDITSPVEGECIELSEVKDDVFASKAMGEGIAVLP
                     TKGVITAPTDCEVASLFPTLHAIGLKLDNGAEMLIHVGINTVELNGKYFTKHVNQGDL
                     VKKGDKLISFDIDKIKKAGYDVTTPVIVNNTFD"
BASE COUNT        16985 a         5716 c         8303 g        15021 t
ORIGIN      
        1 atatatatta tacattatca atgataggtt atataataaa atcactaaca attatattat
       61 aagaaaatta taaaaattac aaggaggtat agaaatgaaa gaaaaagcag ggattagaaa
      121 tgccataata gcagccttta taatcacaat attggcagaa ttaattggac ctatttcatt
      181 taaagttatg ggaattaatg taactttact tagtatacta tgggctatat tcataggaat
      241 ggctgtttct cctcatttat tagggagagt tataccagcc ttaaaaaagt ttatagggga
      301 taatgaaata aatgtatctc catatttatt atctttgaca ctatatccat tagggataat
      361 gtttggaatt aatgcagggc ctaaagttgg tatattactt caagcaggac cagcactttt
      421 attacaagaa tttggtcata tgggtacaat gttgatagca ttacctgttg gagtagcatt
      481 aggtcttgga agaagtgcat taggtggtac tttttcatta tgtcgtgaca cagcactagg
      541 aattattgga gataagtatg gattaaactc accagaaggt ataggaacac taggaactta
      601 cataagtggt agtatatttg gaacattatt attttcattt ttagcaccag tgggtgtact
      661 tttaggattt catccatatg ctttagcaat ggcatcagga atgggtagtg gttcaatgat
      721 gggagctgca acagcatcat taatgaatac ggttccacaa atgtcagagc agattttagc
      781 atattcagct actagtggat tgattacagc tgttactgga atatatatag aattattctt
      841 atctttacca gtagccaact actattatag caaagtagct ccagttattg aaagatttag
      901 aggaagaaaa acaagaagaa caagtaataa attgtaaagg aggatatata tatggaaaaa
      961 acttttaaga ctattatgga gcagataaaa atagtattgt ttatatatat tattatttgc
     1021 tttggacaaa tgatagcact taagactcag gctcaagatt tgttgattgg aagtgtatct
     1081 ggatttttgt tggtgataat tgctattata ataaagaatt ttgttaaaaa acctaattta
     1141 ccaggttttg catgggctac attagttgca ttcgttttat cgcttccaat atctccagtg
     1201 ggggatatca tagcaacaaa tgtagggaaa atcaatttta tgtctacagt aacaccatta
     1261 ttagcttttg caggaatctc tgtaggtaac caattagata tattaaagac tttgagttgg
     1321 aagttagtag ttatatcatt tatagttatg acatctactt actttggttc tgcttttata
     1381 tctcaaacag ttttaagatt aaatggaatg ctttaaggag gtagtaaata tgaatgaatt
     1441 aaaagcaaaa attaaagagg aaataaagtt attatctgaa gagaaaaaga catcatttga
     1501 aaaagtttct gactatttat tttcaaatcc agaattagca tttgaggagt ataagtcaca
     1561 aaaagcatta tgtgatttgt tagaagaaaa tgaatttaat gtaactaaag gtgtaggagg
     1621 attagaaaca tcttttgaag ctgtgtattc aaatggaact aatgggaaaa cagttgcttt
     1681 tttagctgaa tatgatgcac ttccaggaat gggacatgca tgtgggcaca atatcatagg
     1741 gacaagttct gttggtgcag gtatcatatt aaaagaaatc atgaaaaaac ataatataga
     1801 agggactgta aaggtttttg gaacacctgc agaagaaaga gtaggtggaa aaataactat
     1861 gattaaagaa ggtgtattta ataatgtaga tgctgcatta attttacatc caagtgatgc
     1921 ttcaatgcct gatgatatat catttgctca agttaattta aaatttgatt ttactggtaa
     1981 ggcatcacat gctgctgctt ttccttggga agggaaaagt gccttaagtg gagtaatagc
     2041 actatttaac agtgtaaata gcatgagatt acatcttaaa gattatgcaa gagtacatgg
     2101 aattataact gatggaggta gcatacataa tataattcct gaaaaatcta cagctatatt
     2161 taatgtaaga gccttaagta tagaatattt aaatgagatt tgtgaaatgc ttaaaaattg
     2221 tgctaaagga gctgcaattt ctactggaac taatgtagaa atagttcaat tagatgaaat
     2281 atacaaagag attaagaatg attctgaatt agtgaatata gttagacaaa attttgaagt
     2341 tttgggtgaa gactatgttg aaagagattt aagtcaaggt ataggttcaa ctgatacagg
     2401 aaatttaact catgagatac ctgcaataca agcatatata aaattaaaag aaaatactgc
     2461 aactcataca gatgaatttg ctgttgcagc tggtggtgaa gaaggcagag tagcacttat
     2521 aaaagcaatt aaggtgttag caatgtgtgg agtagatatt ttgtatagta aataatatat
     2581 aattttaaaa tatattaaga aaggaaatcg gattagacat gatattaaaa caagtaatag
     2641 aggtttatga cattttagat aaagcaaatg ctaatgggga agaagtaaaa acttacttac
     2701 aaggttatgg tgaagtagat gtaactgtaa aagaattgtc ttcaagtaaa ggctcaacag
     2761 atttagtaaa gcttacaatt cctgggaaaa atggaaaatt aaaaggtgga gatgctccta
     2821 ctcttggcat tttaggtaga ctaggaggga ttggagcaag accagaagtt ataggttttg
     2881 tttcagatgg tgatggagca ttggtagcaa ttgcagtggc tgctaaactt ttggatatgc
     2941 aacgaaaagg ggatatatta gatggtgatg ttgtaatttc aacccatatt tgcccagatg
     3001 ctccaactaa agaacactat cctactcctt ttatggattc tccaattgat atgatgacta
     3061 tgaatgaaaa tgaagttgat agtagttgtg atgcaatact ttctatagat actactaaag
     3121 gaaatagagt aatcaatact agaggatttg caatatcgcc aactgttaaa gaaggctaca
     3181 tattaaaaac tagtgataac cttttagata ttatgcagac tgtaacaggg aaatctccat
     3241 ttgtattccc tttgtctatt caagatataa caccatatgg aaataatctg tatcacttaa
     3301 atagtatttt acaaccagca gtagctacag atgcaccaat agtaggagta gcaattacaa
     3361 cagagatgcc tgttgctgga tgtgctacag gtgcaactaa ttttagtgat ttagattcag
     3421 ctgggagatt tgcaattgaa gttgccaagc tatttggtag aaataagtgt gatttctatg
     3481 ataaagaaga gtgggaaatg cttattaaga gatatggcaa attaaataga tttcaaacat
     3541 ttggtataca gtaattagaa aaatattaag tttatataat ttgtgatata aatatctata
     3601 ctatgtaaac aactagaaac aaaagatata gtttaagact taaaaaataa aatatttatt
     3661 tgattacata aataaggagt gttctattta ggtaagcgcc aataagtagt ataacattaa
     3721 agctaaccta attgttgata tacaagattg aaatgaaaac agtgcgtatt ataagaaaag
     3781 gttacgcact gtttttttcg tcctgttata tagcagaaca ctagttttta agggtatgag
     3841 tataaaactt ttttaaattt catatctacg aattttgtag attgtccata agcgatatgc
     3901 aataattagg aaaatatttt gagtttattt ttcagcttta ataatcattg tgccgttgtt
     3961 ttcatgaagt acatacacag ctctaaagcc tgcatttttc attaagtgta tttgatgttc
     4021 aatagtcaaa ggaatatcaa tatggacaaa aacatcatca ggcacatgat tttctttaca
     4081 tttaaattca tattgttcaa gacaaattgt ttcttcctct aaacaacagg caatataatc
     4141 gcactcaaca taatatcctc caggtttaat tgtttgaaaa agctttttat atatcttctg
     4201 ctttttctga tatttgaaat gatgaagcgt ttcaaatgag agggcagcat catatttctc
     4261 ttgctcaaaa ggatattcaa aataatctgc caagattaaa tcaatatttt tatctgaata
     4321 tttttcttta agcttactca tcatttcttt tgataaatca atgcctgtaa tttgtacatt
     4381 aggaaatttt cgataaatcg atgcaagttc tagaccagta ccacaaccaa tatcaagtaa
     4441 agaagatagt ggagtatcaa aataatctgc tatatgtgca tattcttctg tccaattagc
     4501 aagatgaaca ttatcataaa tatcaattcg ctttgaaaag aaatccgaca tttcttcaac
     4561 cggtttactt ctttcttgcg ctaaccattt tttgaggtca agcatatatc ttttgatttc
     4621 ttcaggtgtt cttattttac tttccaacat ataaaacagt cctttcttta ttcggtcttt
     4681 gttatatcca atgaaaatcg ctcaaaagca ttttcaagta actgttgtac catatctaat
     4741 ggaatgtcta tgccattgga aataatttgt gtagctactc catgagaata aagccaaaag
     4801 ttaataaata gcatttctga tttttctata gataagcctg taactttttt agcattttct
     4861 atagtaattc tgttccattt tgcatgaata atatcttgta aggatgaacc cttcattgtc
     4921 atattcataa ataaggtatt gaaaatcatt ttttcatttt gagcaaattc aatgtatgca
     4981 agtccttgac ttaacagacg attttcatca tttattttac tttccataaa agaattatag
     5041 taattgtcta gttctatttt aatatcttct tttatctcat ccatatttgt gtaaatacga
     5101 aaaaggggtt ttgtagagca attaagggtt tttgctaagt tacgagcatt tacgctactt
     5161 attccatttt ctcttaccaa ctgaattgca gcgttaataa tatcttgttt tgtaataatc
     5221 ggttttggtg gcatcttttc atcctccttt cggtaactta agttgcgcaa ctggtgttgt
     5281 tattataaca aaggcatata actgtgtcaa tagacttcaa agaaaagcta cagacatcga
     5341 gtgtaatatg atttatttca ataaatacca taatatgtgt acttatatct taaaaaggag
     5401 ataaacagta aaatgtagtt tagttaaatt tgaaacttcg tcaaagcttc tttgtacgat
     5461 aagacaacgt acaaatcatt gtatgggtaa cagagaaaga actgcgttga ttgaggatga
     5521 aatctcacat gatacgatgt aattataaaa aaaggagcgt ttcaaagtga tttttttaat
     5581 catcttgaga caactcctta tattttttat ttaaattcta ttttttattg cctgtatagc
     5641 tattttctcc atcataaggt ggcatgacct tgaacagcgt ggttttgtaa agttgggcac
     5701 cacaaaacaa aaaatcaaca agcccttgtg tggtctgctg acgtgtttac tatactatac
     5761 tttatccaaa accgcaagca ctatgggagg ctataaggcg gcggccattc aggggcgatc
     5821 ccctcgaaac cgggataggg ttcccatgtg ggacataata aagagcgccc cggaggtatc
     5881 aactagcatc tggggcgctc tttattatgc cccgtgggaa ccatgcccac gaagcagggc
     5941 gtacaacgga cagataggtc ctaccctcct gacaaactgg aatctccgaa aacaatcata
     6001 acaatcatgg caagattata tacactcctg taaaatattt ttgtgtgtac catgaagtac
     6061 tgcttgccac tattgagaac ggataaaagg gaagtacgta ttataccaat aaggtgcatg
     6121 aaacaaaata ctcatttgat aaagttaaat aaacctgtcg gaaccccacc aatccggcaa
     6181 aagctcactc aatttaacag ttttttctgt ttcgacatta actaaaatct caatacaagc
     6241 actatcctta tcaagttgca ttaaatattc acgacaagca ccacatggtg agccaacact
     6301 cccattgctc atcacacaaa ctaatttagt aattttactt tcgccatttg ttatcatatt
     6361 ggcgatagca tttctttctg cacacattcc caatgtacag gctgtatcaa tacacacacc
     6421 agtataaaca tttccgctgt cggtaaggat tgctgcggca accccaccag catcgataaa
     6481 aggtgaaatt gtgcgtggat ttaattttcc cctagcctta ttataaagtt ccttccattt
     6541 catcaggttg atcctcctgt tgtatccata taaataatct tttatacgcc ttttccgcct
     6601 aaggcacaca acacattact cgcttttttc attctaatat tcgtgcgtga aaatgtcaaa
     6661 cggtttactt cgtttcatta cttcatactg ctgttcataa ccctgtttgt tcacttgggc
     6721 accattagag caccaattta cccgtttcag ggttgtagcg aacacagcag aaatgctcat
     6781 ttcatgggct tttctggcta gaaaaaaaat tttatcgctg ccagatattt actatttttt
     6841 attaagttgc tggagttcca ctaccatcag gaggagtagt agagccacca ccattatttc
     6901 caccattatc aggaggagta gtagagccac caccattgtt tccgccatta tcaggaggag
     6961 tagcagagcc accaccatta tttccgccat tatcaggagg agtagtagag ccaccaccat
     7021 tgtttccgcc attatcagga ggtgtagaac cgccaccatt atcacctgtg ttattattgt
     7081 tattattatt ttcttctggt tggttattgt ctggtttttt tgtatcttca gatgatggtt
     7141 gagaacttac tttagtagga gcagtacctt caataaatgc tgctttagag ccagaagatt
     7201 gctttcctcc atcctctaaa ttaatttttg taaaatatac atttttagga acttcaaatt
     7261 cagtaaccgt taaattagca tgtatttttt ccataatttt ttcccatagt tttgcagtac
     7321 tagtacttcc atgtggtact tctctacgtt ttatagtgtt accagaatca tcttttctac
     7381 cagcatcatc tccaatataa gttgcaccaa cataataagg agtgtaaccg acaaaccaag
     7441 catcatatgc actatttgta gtacctgttt tacctgctac aggcattccc tttggaagtg
     7501 cagcaacacc accagtacct tcagtaatta cactttctaa catatctgta acgacataag
     7561 ctacttcagg ttctacaact ttatgttcct caggagcatt tttaactaat aattgaccat
     7621 caaaggtagt tatagtagta aaaatagaag gttctacata aataccgtga tttgccaatg
     7681 taccataagc agcagccatt tgaagtggag taataccatt cgccatacca cctagtgtca
     7741 atgatgggaa ttttctatca cttgcttcag atgaacctga gtgattattc tttaaagttg
     7801 ttataccaaa gttctttaag taatccatca ttatatctac acattcatca taagagtctc
     7861 caagcatttc agcagttttg acagctatcg tgtttgaaga tttagcaaat gctttacgta
     7921 aactcataga accatgacta gcagtagtag ttcttggatt ccatttatta ttttcttcaa
     7981 acttatatcc tcctcgagaa tcacttagag cagttgcttg tgttattttt agagtatcaa
     8041 tagctggcgt atatattgct aaaggtttta tagaagaacc tggctgatga gggttagtag
     8101 cacgatttaa agtttttcta ccacttatat ttcttcctcc agctagtgct cttatttcac
     8161 catttttata atctaagatt accattgcag cttgcggttg gctaactcca tcaggaccga
     8221 ccatatgtcc tgggaaattg ctatttctat caaattcttc ttctaaagca tcttgcattt
     8281 tagggtctat agttgtgttt acaattagac caccattgta gaataagttt tgagcttcat
     8341 catttgtatg tccttgttcc attaaagcat ttataacttc actttcgata aggtcttcta
     8401 cagatgaaga aactttatct gatgattgag gcaattttat ttctatttta gctttgattg
     8461 cttcatcata ttcactttgt tttatatatt tcaattctaa cattttcttt aaaacaattt
     8521 cttgtctttt tttagcttca ggattactta cagcctttct aacaactaat gtacctgctt
     8581 ttaattgtct ataagtatca ttagatataa gctcccaaga ttttattttt tcaatcatat
     8641 caaagtccac ttgagtaggg tcatctaaat catcatcagt tgtgttaaca aaaaataata
     8701 atttattctc taaatcctcc ttagtttcat ttccctctaa cttagaagtt ttataggctg
     8761 aaaatcttga tggattttta gttgaaccag caagaagtgc tgactctgct agagtaaggt
     8821 cagctgcaga cttatcaaaa taaccacgtg caccagcctc agcacctgct agacctctac
     8881 caacgaagaa gttatttaaa taagtttcta gtattttatc tttacttact gttttactca
     8941 tctcatgtgc atagtaaata tcctttattt tacgaggtat agtttgctgt tcagttgtta
     9001 acagcatttt ggatacctgc ataggaatag tactaccacc ttgcttagta cctgtaaggg
     9061 tctttaatac tgacctaaat aaacctttaa tatcgacacc cttatgctca taaaaacgct
     9121 catcttctat tgcaattaca gcatgttgaa gataagggga aatcttatct aatggaacgg
     9181 gtgtcttttt atttacactt ggagctgtag ataatgtttt tccattagcg tatttaatag
     9241 tagttgtttg gttcgtctgt ttatctaaaa cagcttctgt aactggagtt acatctctta
     9301 gtgacgcaaa tactagacca gcagtacctg ctgtaccaac aactagtaaa actaaaaata
     9361 ctatcccaaa tactcttagt tttttaaatt tatcgctttt tttagatttt ttcttgtttt
     9421 ttgttgaacg agtcttgtta gctgaagttc tattaattgg tttatttgta ttaccagatg
     9481 agctaacttt ttttctcctg attttatttc catttttatc attatcgtta ttcataagat
     9541 tttaacctcc ttacttaatg caatattata acacaaatag gagtagtttt gtaattaata
     9601 gaaaaaatga atttgctata atattctgta cattgtatat gtataaacgt aatatattaa
     9661 aaagtctata tttttatttt atttattttt gacaaatatt ataaaaatta tgccaaagct
     9721 acatataaat aaataggagg ggataatttt gaatagaata gtagatagaa aaacaaaaaa
     9781 tgaatttaga aaaatcatag ctattttttt agtaattctt ttcttgtctg tatttatagg
     9841 cagttttata tatatagata aaactttaag accgacaata acagttttag cagagactaa
     9901 agctcttgaa ctagcaaata ggtcgataaa taaagctgtt gctgagatgg tagaaggaaa
     9961 aataaattat gaagatttaa tggatataca acttgataat aatggtaaaa taactatgat
    10021 acaagcaaac actataatga tgaatgaaat tgcatctgca atagctttag aaatacaaga
    10081 tgaattaaaa aaggataaaa cagcaagttc ttacatacct ataggaacag cattaggaag
    10141 tcctatatta gctaaatacg gtcctaaact tgaagtatct attgaaccta taggaacagt
    10201 atcagtaaac tttaaaacgg aatttgagtc ttcaggtata aatcaaacta gacatagaat
    10261 atatttagaa gctcaaacac aagttaaagt agtaatacca cttataactt caacaaaaca
    10321 aattaaagct caaataccta tttgtgaaac tataatagta ggtgatgttc cagaaagtta
    10381 tgtaaatatt ccagaaaaaa atctaggaaa tgttttacct aacactggaa agaataccaa
    10441 caagtaatat aaagttgtat atttttaaat aaattcaaaa taatagttta taaataaaat
    10501 ttttggaaat aatattaata taattttaat aaaaatttat attttatact atgtaaaata
    10561 tctaatatat ttggtctgta ggttaaataa aagtaccttt agaccaaata tattattaat
    10621 aacttaataa catcttaaaa cttatttatt tatattattt acaacatcca tttaataaat
    10681 acaccataac ctacagctgg gtcgttttca attgcatgtg acactgctcc gattatttta
    10741 ttatcttgaa ctattggagt accactcata ccttgtacaa taccaccagt ttgagctaaa
    10801 agctttttat ctgtaatttt aattttaaaa cttttacttt ctggatgttt ttggttttct
    10861 atatctataa tttcaatatt atatttttta cacttattaa agttatcttg taaaattatt
    10921 tgagcttttc ctaatttaac ttcatctaaa gatgctactt tatatttttt taacttggaa
    10981 atatcaaagt tattaatttg acctcttatt ccaaaatcag tattttctgt aaagctacca
    11041 ataatatttt ctcgttttgc atttatacat ccaacactac ctttataaga tttttctata
    11101 ttaaggtgct tagttgtaga aattgaacct gttttaatag gtatttttct tgcattaccc
    11161 acacttattg gatgacctac agctccaaac tctgatgtat ctggattgat atacgttaaa
    11221 gtagcaaatc cagaaagtaa attgttaaaa ctaatttttt ctaatatgtg tttggtagtt
    11281 ttcattgtta taagttgtcc acctctattt aataaaatag atacttgttt ttcttctggt
    11341 aaagcattta aggtattggc aaagtcacta tatccatcaa cttcagcatt atttaccttt
    11401 actatagcat cacccaatct aaatggagat gcttctccag gatttctaac tatgatattt
    11461 tttaattctg cgtcaatttg aagtacgttt ccaattggta ttaaatattc aggttcattt
    11521 ttttgtaaat tttgtgcata aattaaatta tttgagaaaa aatataataa aaataaaaat
    11581 gttaaaacaa ttgtaaattt tgacttagct aagttggttt ttttacttaa agtattattt
    11641 ttaaaatgaa aatttttaag ttgcataaaa cacctctttc ttattaaatt attttaataa
    11701 tagaattgaa gttttcttgc tgcttctata ttatgttgtg caagaatcat gttttgatgc
    11761 ttggaaaact agctcaataa caccttagtt ttcataaaaa taaataaaat aaatagtgta
    11821 tatgataaaa taaatacata ttcatataaa taaaaataaa caataactgt ctagcataag
    11881 aaaggagcaa aaaatgaaaa aatatagatt gttagttact tgtataattg ccatgggaat
    11941 cataattata ggaacatcaa atccagttag caatttttac aagactacaa atttgattag
    12001 ttcaggaaat atcacaaatg aaaaagcaga taaagatgaa aattcaaaca aaaataataa
    12061 agataaaaat gaagacaaat ctaattctaa aagtaataaa gataagtcat cagaggacaa
    12121 atcgtcagat aataaaaatg aaattcaaaa aaataaaaaa cttttaattt gtatagaccc
    12181 agggcatcaa ggaaaaggag atagcaattt agaaccagta gctccaggtt cttcctctaa
    12241 aaaagcgaga gtatcttcag gaacagaggg tattgctaca aaaaaaccag aatatgtttt
    12301 aaacttagaa gcatctcttg ttttaaagag tatattagaa tctaaaggtt ataatgtaat
    12361 aatgactaga gagacacatg atgtaaatat aagtaattca gaaagagcaa tacttgctaa
    12421 tgataaaaaa gcagatatgg ttgtaagaat acatgcagat agtttaaata attcttcaaa
    12481 aactggagca tctatattga ttcctgaaaa agatggaaaa tatacagctc ctatatatga
    12541 agaaagtaat aaatgtgctg aatttatcaa acagaatatg gaacaatcag gtatacaaat
    12601 caatggaatc gttcaaagag gcgatttgac tggattcaac tggtcaaaag taccagctgt
    12661 attagtagaa atgggattta tgagtaacta taatgaagac caaatgatgt caaatccaga
    12721 ctaccaaaga aaaatgatgc agtgtatagc tgatggattg gatgcgtatt ttaaataaga
    12781 tatgaataga gaaaaagtta ggttggtatt attttcctaa tttttatctc tattttttat
    12841 tgtacataac acaaagaaga agtttatttt aggttaaatt gtcgtaaata taactaaaaa
    12901 tattgggaat acttgattta agtttaaaaa gaatatatta tagtatagaa tgtgtaaaat
    12961 ttttttgaga ggtgttgaaa tgctagtagt agaaaatgtg agtcatggat ttggtgcgag
    13021 aacaatatta gaaaatgtat cctttagact tagaaaaggt gaacatattg cactagttgg
    13081 tgctaatgga gaaggaaaat cgagtttttt aaatataata acaaagaagc ttatgccaga
    13141 tgctggaaat ataaaatggt cttcaagagc tacagtaggt tacttagacc aacatacggt
    13201 attaagcaag ggaaaaacta taagagaagt gcttagagag gcttttaagc atatgtttga
    13261 cttagagcaa gaaatgattg ctatgtatga caaaatggga gaagctagtg atgatgaaat
    13321 gagtaagctt cttgaagaaa cagcagagat acaaactata cttgaaaata gtggttttta
    13381 tatgatagat gcaaagatac aagaagttgc aaatggtctt ggtcttggag aaattggtct
    13441 tgataaagat gtaactgact taagtggagg gcaaagaaca aaagtacttc ttactaaact
    13501 tctacttgaa aatccaacta ttcttatatt ggatgagcct acaaactatt tagacgaaga
    13561 gcatataaca tggcttacta agtaccttca agagtatgag aatagttttg tcttagtttc
    13621 tcatgatatt gaatttataa ataatacatg taatgtaata tatcatatgg aaaatggaga
    13681 gttaaataga tataaaggaa attatgatga atttgtaaga cttaatgata taaagaaacg
    13741 tcaagaagaa caagcttatg ataaacaagt tgaagaaaga aaaagactag aggattttgt
    13801 agctagaaat aaagctagag tagcaactag aggaatggct aacagtagac aaaagcaact
    13861 tgataagatg gaaatattag aaagaccaaa agaaaaaata aaacctactt ttgcttttaa
    13921 agatgctaga gcagctagta aaataatttt tgaaacagaa aatttagttt tagggtatga
    13981 tgaagcattg acaaaaccac ttaatttcca tttagaaaga ggaaaaaaga ttgccttaaa
    14041 aggaatgaat ggtattggaa aatctaccct attaaaaact ttacttggaa taataaaacc
    14101 atttgaagga aatgttaaat taggtgacta tttggaagtt ggatattttg aacaagagag
    14161 ttcaagagaa aatagtaata cacctatgga tgaagtttgg agtgaatttc cagggcttac
    14221 aaactttgaa gttagacagg ctcttgcaaa atgtggactt acaaatgaac atataacgag
    14281 tcaaatgaga gtattaagtg gtggagaagc tgctaaggtt agactttgca aagtaatgtt
    14341 aaaaaatata aatttcttag tattagatga gcctacaaat catttagatg ttgaggcaaa
    14401 agatgaattg aagaaggcta tcaaagagtt taagggaaca gttcttttag tatgtcatga
    14461 gccagaattt tattcagaaa ttgttgatga tgtatggaat atagaagatt ttacaactaa
    14521 aatcgtgtag tgatttaact tattgctggg gggatttcat gaaaaagttt ctaaatgtac
    14581 ttttttcaat ttgtattagt attgttataa tagtaggtgt tattaatttt actgttggat
    14641 ttaaacaact ttattatttt gacattgatt acttaaatat atcagagtta tctggtttat
    14701 ctaaagatga tataaaattg aactacgatt atctaattga ttataactta aataagaatg
    14761 tgtctgagtt caaattacca acattaaaat cttctccaca agggaagata cattttgaag
    14821 aagtcaggaa tatatttcaa aatataaata aattagctaa attattattg gtagtttctt
    14881 tagtaggaat tatattgagt gtaaaaaata aaaatataaa aatcttaaaa actacatcaa
    14941 taacacttat aattatgcca ttattattaa cagttccaat tttattaaat tttgaaaagt
    15001 catttattat ttttcataaa ttattattta gaaatgatta ttggatattt aatcccgatt
    15061 tagacccagt tataaatata ttgccagagg aatttttttt tcactctgga atgatgattt
    15121 taatattaat tttgttagta agtatagtac tgtttgtaat gtataaatta tgtaaatctt
    15181 tatcaataaa aatatttcaa tgttaaatag agggatattt ttatttccaa aataagataa
    15241 taaaaaagga ttagattaaa agttatacaa taaaaatagc tgtgcaataa tatttagact
    15301 atgaaagtag ttgaaaaata tttatgcaca gctatttata atagaattta ctttttacta
    15361 gtgattttaa ctaaatcttg aaatttactc ataatgtaat tgtaattatc ttttttatga
    15421 ggtaatatac aactactgca atctttgata cctttatctg tatacttaaa gtttccacca
    15481 cagttttctc ctaaagcata caaaggacaa tagcaaaata gacagttaaa ctcttctggt
    15541 ttattagttt tatgacaagg gaaaaattcg caatctttgt gattaaaaaa cttataattt
    15601 tcgcccatat tttcctccta attaaataaa atttaaattt tttatactat ataagatttt
    15661 ggtgataata taattatact aaataatttt atgaatagtc gataatatag tattattaat
    15721 catagtatta atggtataat tagtcaacag aaaaataatg taaaaataat gtaagtgtat
    15781 tttgtaatta gaatatgttt tataacaaaa aatgaggtga ttaagtgaaa gaaattcaag
    15841 aaaaagcact tcttgtaggt ctgaatttga ctacaatagt gaaaaaaaat gatgatatag
    15901 acactaatga atctatggaa gaattaaaag aactaacaaa agctgctggg gcagaagttg
    15961 taggtagctt aattcaaaat aaacactctg tagatgcagc ttattatata ggaaaaggta
    16021 aagtagaaga aataagagcc tatagtgact ctttagatgc tactttagta atttttaatg
    16081 atgaattatc tggtgctcaa atcagaaata tagagaatgt tgttggaaga aaagtaatag
    16141 atagaactac tttaatttta gatatatttg ctcaaagggc acttagcaaa gaaggtaaat
    16201 tacaagttga attagcacaa ttaaagtata gattgccacg actttatgga atgggtggtg
    16261 agatgagtag aacaggtgca gggattggta ctagaggtcc tggagaacaa aaactagaaa
    16321 tagataagag acatatactt aataaagcag cagatataag acgtgaactt aaagaagtaa
    16381 aaaagaatag agagacacag agagttaagc gtttaaagtc aaatataccg attgtagcac
    16441 ttgttgggta tacaaatgca ggaaaatcta ccctgttgaa cgaattaata aagacacaca
    16501 aggattatga acaagaaaaa gaagtttttg taaaagatat gctttttgca actttagatg
    16561 taactttgag aaaggctctt ttgccgaata aaaaagaatt tttagtagta gatactgttg
    16621 gatttgtaag taaacttccc catgatttag tagaagcgtt taaggcaaca ttggaagaag
    16681 tacagtatgc agatttaatc ttacatgtaa ttgatgcaac aaatactagt tatgaattgc
    16741 aaaaaagtac gactgaaggt gtattaaaag aacttggtgt aaatgataaa aaacatatac
    16801 ttgtatataa taaagtggac aagctagaat tggatatata tcctaaaagt caagaagata
    16861 ttgtgtatat ttctgcaaaa caaggcataa atatggataa gttattaaat atgatagaaa
    16921 ttgctttaat ggaaaatacc tattcagtaa ggttgatgtt accttatgag agaggtgata
    16981 tatttagtag aataaaagat aaatataatg tggagaattt tgagtatggg gaaagtggta
    17041 taacgctaga tgtagattta gatgaagaag attttaatat ctatagagag tacatactag
    17101 aaaaataggt tgaatatgga tataaactgg gaaaatatag ataatcttga agattatttt
    17161 ataacctatc ttctttataa agaatctaaa acagtatctc aaattagtaa aattagaaat
    17221 atttcaagta ctgaagcaag tgagcaactt atacaagcaa agttaaaaat aaaggaaatg
    17281 caaaaagatg attttgaggc atctaaggat attttggata aatttctaga actagataaa
    17341 attaagagac ttgattttat ggatagctta gatgacgaaa aaatggtata ctttaagaga
    17401 aaggttttca aaagaatcct tgtagaaaaa aatgctgaag atttaattgt tttaatttgg
    17461 gcgacaggtg agctaaaaga tgataggttt ttgaaattgc ttcatcagct cacaaaccac
    17521 agacactcag atattagaag aataacttat tcagcaatca gaaagattga atcaccaagt
    17581 agtagagaag tactgcaaaa aggtctctac gacaaaaatg cacagactag gcagtactgt
    17641 gcaaaagctc tttcaaaatt gggagatgaa aacagtttaa agattttaca gcagttgaaa
    17701 gacaagaata agaattttga aaaagaatat gtgcttagag cttatgacga agccattaag
    17761 tcattggaaa atgcaaaaaa tttgaaaaag taatttttta ttaaagcaat ttgtttactt
    17821 aatgatgtat ttctaaagtt taacaaggta ataaataaat taatgggagg ggtttcaaat
    17881 gatagtaaga cgttgtgcag gtggagtagt gttttatgct aataaagtac ttattgtaaa
    17941 aaatgatagg ggtgaatgga cacttccaaa aggaaagata ctaggagggg gacttccata
    18001 tgagagtgct gttcaaagag ttaaagtaga aactggcata gatgctaaaa tgatagatgt
    18061 ggctggcgat actatgtatg aatttttctc aagaagtaga caacaagaag tttgtaatgc
    18121 aataatgtgg tatgttatgg aagcttgtaa cactgattgt gtacttgctc ctgaatttca
    18181 agaaggtgga ttttataaag taaaggatgc tttagaaatg ttatcacatc ataaagagca
    18241 agctttagta gaagtatctt ataaaaagtt taaggaatta aagaaattag tttcagaggg
    18301 cgatgatgtt ccagcaaatt aattgtgaat ttagaggatt ctgaggaagg gatagcccct
    18361 tcctttttta attgaagcag ttttaagcgt aaattatata gtctctttaa actatgattt
    18421 atcaatttag agatttagta gtttatattt aaaatcagta agatatgttt aaaataaaaa
    18481 ttaaaaagta tacaatttta ttatataatt gtcttatgat gttgattaaa gaattattaa
    18541 aagtccattt atttttaaat agaataattt tataaatata tatttgatgt gtatattaga
    18601 aaatgattaa aataggagga aatacaatga gcaattacag gacattacat gaatttggaa
    18661 cggatgaaat aacgattgaa aagtctgttt ttattggata tgctaagcct ataaagagtg
    18721 aagaagaagc attagagttt ataaatgaaa taaagaaaaa gcataaagat gcaactcaca
    18781 atgtgtgggc ttatactgta ggtaaaaata tgaatataca aagatatagt gatgatggag
    18841 aaccacaagg aacagctggg atacctacat tagaggttat aaaaaaagaa gatttgagag
    18901 atgtagcggt tgttgttact aggtattttg gaggaacaaa attaggtgca ggtggtctag
    18961 ttagagctta tacaaaaggt gctaaactgg gacttgaagc aggtaagata atttataagg
    19021 taatgtatca agaagttaag gttaagatag attatactca acttggaaaa gtgcaaaatg
    19081 agttaatgaa tttggggtat tttataaaag atactgtata tgaggataat gttgaaatag
    19141 tagtatattc aagattagaa gatgtagaga aattatcaga aaaaatgatt gatataacaa
    19201 gtggaacagg aaaaatagtt ttaggagagg aattttattt gtctgaacaa aatggagaaa
    19261 ttttaatata atctaaaagg ttattagaat agttaatacc tcaaatagcc aattagtatt
    19321 tttaagtgaa aagccattaa attgatttaa tctaaatcaa tttaatggct ttttatcgga
    19381 ttttgcacag aatccttttt ttacttcaaa taaaccgact aaaagtaaaa atatcccaaa
    19441 tatttttttt aatatatctg aagacagata attagctaat agtgaaccaa atacagctcc
    19501 taaaacccca aacacagcta taggtataac caatttaaaa attacatttt tattttttat
    19561 atgtatagca agtgctataa gtgtcatagg gatagatgaa agtaaattta cgctttgtgc
    19621 tattttagtg tctatgccag caagtaaaac gagtgcaggt ataaggattg ttcctccacc
    19681 cattcccatt cctccaataa ttcctgcaaa aaatccaatt agagcaaata acattaaaac
    19741 accatcctta atgctgcaat tatcataatt attccaaaag aaattctaag aaactttcca
    19801 gtaaccttat ttagtaattt agctcctata ataccaccaa gaatacttcc aactgcaact
    19861 ttaattgtta agttaacatc ataagtacct ttagatacat ataaaacaga acttgctgtc
    19921 gttaagaata ttattataga aagagcagtt gcatgagatt tatgttcttc taccttaacg
    19981 atgtcattta atattggaac taaaagagta cctcctccag aaccaaaaac tccatttata
    20041 aatcctgtaa aaactccaat tatcgtattt tttaagttaa aatcaaagta ttttttcttt
    20101 aaatcatcag tttttttcat aaaaatcacc ttctgaaata gttttaccaa aataggcaaa
    20161 ttatatttat ataaaataag attaaatata atctttcata tttgtttaat tttgcataaa
    20221 aaaaaacata ttaaaacaac atattaatat atggtataat atattaaaac aaagtagcaa
    20281 atttgagagg agataacaat gtcaaatata aaaatacaaa tagacaaaac tgtagaatgg
    20341 cttataaata aggttaatga ggcaaatgca aaaggattaa ttgttggtgt atctggagga
    20401 attgattcgg cagtagttgc taatttaatt aaaaaggcat ttccagaaaa ctctatggga
    20461 gttataatga gcataaaaag taatcctcaa gatagagaag atgcacttaa ggttatagag
    20521 ggatgtgata tagaatacct tgatttagac cttatagaac cacaaagtgc tatattagac
    20581 atggtagtag gaaatttaaa agataaacat ttatatagag aagaatattt aaagatgaca
    20641 gatgcaaact taagagcaag agtaagaatg agtacaattt atacaattgc taacaatcta
    20701 ggatatctgg ttgttggtac agacaatgct gcagaaatac acacaggata ttttactaaa
    20761 tttggtgatg gtggagttga tattttacct attgcaaatt taactaaagg agaggtgtat
    20821 gaatgggcaa aagagcttgg tgttcatgaa gatttaataa acaaagctcc ttcagcaggt
    20881 ctttgggaag gtcaaacaga tgaagatgaa atgggaacta cttacaatat gatagatgct
    20941 gtgttagaag gtagattgga tgaagttcct aaaagagacc aagagataat tgaaagactt
    21001 catagattaa gtgaacacaa gagaaaaacg cctgcacaac ctcctaagtt ctaatttact
    21061 atttataaga tttgtgataa aatttacaag tgatgaaaat tagaataatt aattgtacgt
    21121 attaaggagt ggaaatatgg gacgtatagg taatataatt aatagaaaag gtaaacaaga
    21181 tgctcaaaga gcaaagatat ttactaaaca tgctagagca atagcagttg cagctaaaga
    21241 aggtggagca gatccagagt acaatgcagc gttaaaaaca gctatagaaa aagctaaggc
    21301 agataatatg ccaaatgata atatagatag agctatcgct aaaggtgctg gagcaggtgc
    21361 tggagaagac tatgaaacta tagtttatga aggatatgga cctggtggag ttgctgttat
    21421 agtagaaact ttaactgaca acaaaaacag aactgctggt aacgtaagat attattttga
    21481 caaaaacgga ggaaacttag gaactagtgg atgtgtgtct tttatgtttg ataaaaaagg
    21541 acaaatatta gttggtttag gagatggagt ttcagaagaa gaattgatgg atgttgcatt
    21601 agaagcagga gctgaagatt tcataacaga agaagatggt tatgaaataa taactacacc
    21661 agaagatttt tctagtgttc gtgatgagtt aaaagctaaa ggatatgagt ttatatctgc
    21721 tgatgtgaag atgatacctc aaactacaac tgtattgact gaagaatctc atttaaaaat
    21781 gatgaataaa ttagttgata tgcttgaaga agatgatgat gttcaagata tatatcataa
    21841 ctgggaagta gaataaatag tataagcata ttgaaattta taagtattga atcaatttta
    21901 acatgtgata aattttatag aataagaaac actaaaatag acatacgcac ctctaaccta
    21961 tatttgcata ataatatgta agcataggta aggggtgttt ttatatttat aggttaagaa
    22021 atttaaagta aattttgagc tggactcgat tgtctataaa taattgatgg gtatataact
    22081 tgttgctgaa taccatttat acgcccagtt actgtatcaa taatcatcct aagactacgt
    22141 tctgctgtct cttccatttt taaatctata actgtcaaag gaggaatact tcttgccatt
    22201 agtcgtgaag gtccattact tgctgcaaat atttgaatat cctctccaat tacaattccc
    22261 gattcatgaa atgcattcat cataccaaga gctaccacat catgattaca aaaaattact
    22321 ttttttagtg aattttttgc aagcattttt tgagcaatat catatccact atctatttta
    22381 ttagaacaat aatatataga atctgataga tgtattccat gttctttaca tgtttttaaa
    22441 aaagatttac cccttaaagt catacatgta aaggaagttg ggttgaatac aacagcaata
    22501 tcatttttac cattttgaat agcatgtaaa gctgctatac gaccagtttc ctcattatca
    22561 atagatacac ttgaaaaacc aggtatttca cgatttacaa caactacagg aattttaggt
    22621 ttatttttta ctagatattc tatatcatca gcattgatac ctgttaaaac aattccatca
    22681 taataattat ttgcaaaaaa gtattcatca tcacatagat gaccaacttt gtaaggtcgt
    22741 atgatgatat ttatgtttaa atgttctaaa gaaattatgt ggtttattgc ttgaagtata
    22801 ttggttgatg ccaactcaaa tccctcatcc tgccaataaa aagctatttt aatattatta
    22861 tgtttaatag gagtagagcg tttatatcca agcttatcag ctgaatttaa tataagctct
    22921 tgtgtatgta gcggaatcct gcgttcattt cctttaccac ttaagacgta cgagacagtt
    22981 gctgaagaaa gaccacagtc ttttgcaata tctttgattg ttgccatgat aaaatcctcc
    23041 ttaaatagtt gcttaaattt gcttatacca ataatcttaa catatattca actaaagaac
    23101 aatattctac aagttgcata ttttacagga ttagaataaa taaatttaaa aaaacttctt
    23161 acttatgttg acataattta gtttatagga ttataatatg cttaaataag cttataatta
    23221 acttaaatta agcaaagtta agcagggaca tgcaatgcta gcttgcaatg tgactgtaaa
    23281 gggggaaaag gtatgagtaa ggtaaatata tttgaagttg gtcctagaga tggatttcaa
    23341 aacctgaaag agtttttaga aactgataaa aagcttaaga ttattgatgg tcttattgct
    23401 tcagggatta aacaacttga aattagttca tttgtaagcc caaaagcaat acctcagatg
    23461 aaagatgcaa aagaagtagc aacttattgt gtagaaaaat atcctgatgt gaaactttat
    23521 gcattagttc caaatttata cggtgctaaa gttgcatggg agtgtggtat aagagatata
    23581 tcctatgtta tatctttgag tgaaactcat aataaaaaaa atataaatcg tacccatgaa
    23641 gagtctattg atgagcttaa aaaaataatg aatacttatc cagacatgaa tatatgtatt
    23701 ggaatggcta ctgtatttgg atgtcctttt gaaggtttac caaaaattga agatgccata
    23761 agatttgcta aatgcctttg ggaaaacggt atcagggaga taaatctagc agatacaata
    23821 gggattgctg accctaagca agtaagagaa actattagtg cattagttga agctttacca
    23881 gagtgcagat ggcaagtaca tattcatgat actagaaata tgggaatggt taatactctt
    23941 gtggctattg aatctggaat tactactgtt cagtctacac ttggaggatt aggaggatgc
    24001 ccatttgctc ctggagcatc tggcaatact gcaactgaag atttagtata tatgcttgaa
    24061 cgtatggggt atgatacagg agttgatttt gttaaacttc ttgaattatc aaagtatcag
    24121 aagagttttg taaatggagt atatagtggt catcatgtaa atataaagtc tgatagttgt
    24181 aattgttagt tctattgatt aatcgattaa aaaatatgtt gattaaaaaa atatgctgat
    24241 tggtaaaata gatttattga taaaaaatat aaattataaa atacattatc taataaaaca
    24301 aataaaaaaa ttgaggggga ttagtatgga tattatagct ttacttttat ttttaggagt
    24361 tattattatt gcatttgtac gtaagaataa tgcaggtatt ttggctctag ctattggtgt
    24421 catagctgtt agaatttttg gaatggatga taaagaactt tatggagcta taagcaactc
    24481 aatgtttact acacttgttg gtataacact actctttgca atagtgaact caacaggagc
    24541 attaaagctt gttgcagaaa aaattgtagc tgcttctggt aaacgtgttt ggcttatacc
    24601 tatagcagtt tttatagcag gatttgttgt tgctggtgtt ggacctgggg caattccagc
    24661 acttgcaatt atcccagcaa tggctgttcc tgtagccata acagttggtt ataaccctgt
    24721 aatgcttgca cttataggtg aatgtggatt aatggcaggt cgtatgactc ctattactcc
    24781 agaaggtcaa attataacaa ccgttgcaga aggggttgga attgaaaatg ttatgcctac
    24841 tatcttagcc tgtcaaactc tttctacaat tgtattttca atagtattgt ttataatttt
    24901 caaaggatat aaacttaaaa aacctataaa tgttatagat agtaagcaaa tagaaaaatt
    24961 caatataaag cagataattt ctctaataag catagtagtt atgattgctt ttatcataat
    25021 ctttgatatg aatgttgggc ttgcagcttt tgcagtttca gctgtactta tttttttcaa
    25081 tattgctgat gaaggagaat gtatcaaatc aattccatgg agcacgatag taatggttct
    25141 tggagtaggt gcaatgatga caatcgtaga tgcagcagga ggtattgact tgatgagtaa
    25201 tgcattatca tcactgatga atagtaaaac agctactcca attatgagta tttcagcagg
    25261 acttatgtct atggttagtt ctgctttagc agtagtttat ccaactatga tgcctatgtg
    25321 tgttgatata gctaaggcag ttggaggagt agacccacta gcacttattg ctgcagttgg
    25381 tgttggaggt tctcttgctg gtgtaagccc actttctact ggtggggcat tgattttagc
    25441 agctatgggt tcaagtaaga aagactttaa taaggaggaa caaaataagg tttttgtaca
    25501 gcttttcatt atgagtgcag ttggcttatt ggttattgca gtagtatcaa tattatcatt
    25561 taatgcaata acacatttaa tgaactaatt agaataactg aaaataaatc attaaattta
    25621 acttttaata ttaatcaata taatataatt tggaggggaa gttatgaaaa aaggagcatt
    25681 aagcaatata aaggtacttg accttacaag agttcttgca ggtccatatt gtacaatgat
    25741 gttggcggat tttggagctg atgttataaa aatagagatg ccaagaaaag gtgatgatac
    25801 aagaggtttt ggaccttttg taaatggaga gagtttatac tatgcaaata taaatagaaa
    25861 taaaaaaggt atcactctaa accttaaatc agaagaagga aaaaatatat ttttagaaat
    25921 ggtaaaacat gctgatgttg tagtagaaaa ttacagacca ggtgtaatgg aaaagttagg
    25981 tctgggttat gatgagttgg ctaaagttaa caatcaaata atttatggag ctgtatcagg
    26041 atttggatgt tatggaccat attcagaacg tccaggttat gatattattg cacaggcaat
    26101 gggtggtctt atgagtataa cagggcaaga aggaggagaa ccaacgagag ttggtaatgc
    26161 tatgggtgat gtactaggtg gaatgaattt aactattggt atactcacag cactcaacgc
    26221 tagaaaaata ataggaaaag gacaaagagt agatgtttcc ctcgttgatt ctgttgtatc
    26281 gtctctcgaa actggtatac agagatactt tgattcagga caacctgaac ttatgggtaa
    26341 tagatatgct tcagcctatc cttatgactc ttttaaggca agtgatggaa gttttgtaat
    26401 aggctgtggt aatgacaaac tttttgaaaa gttatgtaaa aaagttcttt ttagagaaga
    26461 ccttttaata gatgagagat ttaaaacaaa tcttaatcgt tgtgaacatt acaaggctct
    26521 taaaccagaa atagaaaaat ggtctgttaa gcatacaata aaagaagcag ttgacttaat
    26581 atcagaggct ggagttcctg ctgctcctat ctataatctt gattgtgtta caacagataa
    26641 acatatagca aaagcaagag aaatgattgt agatattagt catcctatta taggaaatat
    26701 gaaagtcaat ggaaatccag ttaagttgat gacaacaaaa gctaaaattg atatgccagc
    26761 accatctcta ggggaaagta acgaggagat ttataatggt tggcttggtt ttgatagtga
    26821 taaaataaaa gatttaaaag aaaatggagt tatttgatta aaaaatagct aaacacactt
    26881 gtgactttag tcatgggagg ttcagttaga ataatatcaa aaaatattaa atcaatactg
    26941 taaatcaaat atagaattgt cagaagcatt taagatggga aaagctactt agacattgag
    27001 tctttgtggc ttttcctatt ttcattaaga attttatatt atcagaatag atatgtacta
    27061 aactaaagta ttaacaattt aaattaatag aaaataaact acctaattat gttgaataaa
    27121 gactacttta gtgaaaacaa acttatagag atgctattta aattatttta atggaaatat
    27181 caaaaatgag actgcattct caaaaatgag actgcgtttt ttaagtattt tctcgaaaat
    27241 gagacaaaaa tattgtttta tgggttttat tgaagaaaaa ttcttctgtg aattacaatt
    27301 taatcaattt taaagttgaa aattattaaa aatttagtga aatttatgta tatttcgttt
    27361 attttattaa aaataacaat tttttactaa aaataaagaa cttcaatggt gattggcata
    27421 gtacttgcta ttttatatta acaagaaatg tagaaaaaat aacaatgtat aatgggggga
    27481 atatgatgga atctgtaatg gaaaatttga acaatcttaa ggtggaggtt aaggacaaag
    27541 tctgtgttat tactataaat agacctaaag ctttaaatgc tcttaatagt gacactctta
    27601 gggaactatc acaagttatt gatgtagtat cagaaaatga ggcaatatta ggagttatta
    27661 ttactggaga aggtaaagtt tttgtagccg gtgctgatat acgccagatg caaaactata
    27721 aaagtgagga aggcagaaaa tatgcaggtt atgctcaggg aatttttgat aaaattgaag
    27781 ctcttgagaa aacagtaata gcagcagtta atggatatgc attaggtggt ggatgtgaac
    27841 ttgctatgag ttgtgatatt agaattgcat cagaaaaggc tatatttgga caacctgaag
    27901 ttaatttagg agttattcca tgttttggtg gaactcaaag attatcaaga cttgttggaa
    27961 ctggaatagc taaagagtta atttttacgg ggagacaagt aaatgcagaa gaagctaaat
    28021 ctattggact tattaataaa gtggttccaa gtgatttact tttagaagag tctatgaaga
    28081 tgatgaacca aatagttgaa aaagcgccaa tagcaataag atatgcaaaa gttgttatta
    28141 acaaagggat agatatggat ttaaagaatg ctcttgaact agagaaagat gttgcaggtt
    28201 taacttttgc tacaagagat aagcaagaag gaatgaatgc atttatagaa aagagaaagc
    28261 cagtttttga aaataaatag ctattataac taaaattgga acaatgtaga atatattcaa
    28321 aatctaaatt tcgtgaaaaa atacatatag tttaatttta aaaggagtta atttatgaat
    28381 acgggagtaa ttataagttt agtagggatt atcatagctc tatctcttct agttgtaatg
    28441 gttatgaagg gaataaatat ttttattata gcaattgtat gttcatcatt agttgctata
    28501 acaggaagcc taaatgtgta tgatgcactt aaagtggatt atatgacagg gtttgttgga
    28561 tttcttcagg caaatttctt tattttccta acagggacat taatgggaaa aataatggag
    28621 attactggtg gagcaaaatc tattgctaag atgattgtaa gatggattgg gaaggataaa
    28681 gcactacttt ctattccaat agcttgtgga atattagcct atggtggagt aagtgttttc
    28741 gttgtaagtt ttgcagtgtt tccgatagct ttagaaattt ttaaagaagc tgatttgcca
    28801 cgaagattta taccagcagc tttgactttt ggatgctcaa cttttgctat ggttgcacca
    28861 ggggcaccac aaattcagaa tattgttcca gcatcaacat tagggacaga tattatggct
    28921 ggagcagtaa atggttttat atcatgtgca gtaatgttta tagttggaag tacaattttg
    28981 tacaaaatgg tttcaaaaga aaaagccaat ggtggtcatt ttatagcaca tgaatcagat
    29041 atatttgatg aagcagaagc aactaattct aagagagaaa atggtcccaa tggtgtaatt
    29101 gccttaattc cattgatagt gtcgatttta ataattaatg taaaagttaa tggaaaagcg
    29161 atagtaccaa ttgaggtggg agtatttatt ggagctttat tagtatattt attgttaaat
    29221 aaatatcaag ataatactaa aatagttgga catgttggtg atgcatgtaa aactacagta
    29281 gtagcaatat gtaatacttg tgctgtagtt gcatttggtt cagtagtaaa atcagcagtt
    29341 ggttttgact tcatagttaa tgctatgact aatattcctg gtcctcctat tgcaggggct
    29401 gcagttggaa ctacagttat tgcaggtatt tgtgggtcag cttcaggtgg actaggaatt
    29461 gcagctccac ttcttggacc agtattttta gccaagggtg tttccgctgc agcattaact
    29521 aggactatgg caatttcatc agcagcatta gattcacttc cacacaatgg atatattgtt
    29581 actgtaacaa atggtctttg taaagaaaca cataaggatg cctatatgcc aatattctgg
    29641 gtaactgttt taaccccatt tattggaacc atagtagcag tcctactgtt tacaatgttc
    29701 ccgggattgc cataggagaa aagataaaag gtataaatta tattttgata ttataaaatc
    29761 aattttcaaa atatatacaa taaatttcat gttttaatac tgtaaatatg tatttaaaat
    29821 aacaaattga ccatataagg aggaattgaa agtgttaaat aaaccattag agggagttaa
    29881 ggttattgac ctaacgtatt ttgtagcagg tccagggact tctaaaatat tagctgactg
    29941 gggtgctgac gttattaagg tagagccaag ctttggagac ccaggaagaa agacaggggc
    30001 aacaatgaca atgccaatag atgattataa taatcctttt tacagcacat ataattcaaa
    30061 taaaagaggt ttgtctataa atcttaagag tgaaactgga attgaaatta tggataagct
    30121 tttaagcgaa gcaaacgtat ttgtttcaag ttatagaaca ggagcattaa aaagactagg
    30181 tcttgattat gaatcattaa gtaaaaagca tccacacctt atctggggtc agataaatgg
    30241 ttttggcgat tttggacctg ctaaggataa tgcaggattt gatacagttg ccttttgggc
    30301 aagaagtggg gctatgcttg atatagcaga aaaagataca agtccaataa atccacctat
    30361 agcctttgga gatgcaacaa cttcttgtag tttatctgga ggaatatgtg cagctttgta
    30421 ccagcaagct aagactggaa aaggacaaaa agtaatggca tctttatttg ggcaagcaat
    30481 atggaatgca tcatctttat tagcatctac acagtttagt gatgagtatc caaaaactag
    30541 aaaaaatgct atttcaccag taataaattc ttatcgttgt aaggatggaa agtggatatt
    30601 cttaagtatt ttagagcatg aaagatattt tgaggcactt tgtagattat ttggaagaga
    30661 agacttaata aaagaagaga aatttgcatc ttcagtagaa agtaagaaaa atgctacaga
    30721 acttattaat attttagatg gtgaatttgc aaagtttact caaaatgaga tggttgaaaa
    30781 acttactgct gctgatatag ctcatgaaaa aattcaacat gttaatgatg tagtgactga
    30841 tgaacaggct attgctaata actatatata tgaacataca agtaaagatg gaaataagac
    30901 aatgcttgca tctactccag ttaaatttgg aaatattgaa gttaacatga cttgtgatgc
    30961 tccacttata ggagaacatt cagatgagat attgagagaa cttggataca gtgattctga
    31021 tatagagact ctaattgaat ctggaattgt aacaatgaat aaagaagcat gtgaaatatg
    31081 ttaataaaca tgtgaagtat gttaataaat aggagggaat tttatggatt ttagattaac
    31141 agaagcacaa ttaatgcttc aaagagtagc aaaagaattt gcagagaatg aaatagcacc
    31201 aatagctgct gaaacagata aaacaggtat ttttccaagg gagcttttta gcaaaatggc
    31261 taaaatagga tttaatggaa ttggaacacc tgtagagtat agtggttctg gtggggcaga
    31321 tatagaaaag gtaattgttg ttactgagat tgccaaaaaa tgtgcagcat ctgcagcaat
    31381 attatcaata cacacaatat atgctcaagc tattttgaaa tttggtactg aggaacaaaa
    31441 gaaaaaatac cttccaatga tggctgaagg tgggtgtgta ggtgcttttg ccttaaccga
    31501 acctaatgct ggttcagatg ctgcgagagc tgcaacaact gcaattattg atgaagaaac
    31561 tgatgaatat gttttaaatg gaactaagtg ttttatttct ggtggaggtc aagcagaatc
    31621 attaataata tttgcattga cagacccatc aaagggaata aagggaatgt ctgctatcat
    31681 tgtcgacaaa ggtactccag gtttttcaat aggaaaaatt gaagaaaaaa tgggtattca
    31741 tggttcagaa actgcagagt taatatttga taactgtaga gttccaaagt ctaacttatt
    31801 aggaaaagaa ggtaaaggat ttaatatagc tatgacttgt ttagatggag caagaattgg
    31861 agttggagct caagctgtag gaattgctga aggggcttta gaagaaagta tcaaatattc
    31921 taaagaaaga gtccagtttg gcaagccaat ttcagctttg caaggtattc aatggtatat
    31981 agcagatatg gcgacaatgg tggaatcagc aaaattatta gtatattatg ctgcagattt
    32041 gaaagctaga ggagaaaaac acactaaaga agctgctatg gcaaaataca atgcgtcacg
    32101 tactgcaaga gaggttacaa atttagccct tcaaatccat ggtggatatg gatatatgaa
    32161 ggattatcca ttagagagaa tgtacagaga tgccaaaata acagaaattt acgaaggtac
    32221 ttcagaaata cacaaagttg ttatttcaag agcagtacta ggataggagg aaaagaatga
    32281 atatagttgt ttgcttaaag caagttccag atactaatga agttaaaata aataaagaga
    32341 caggtactct aataagagat ggtgtaccaa gtataatcaa tccagatgat agaaatgctt
    32401 tagaagaagc tctaaaaatg aaagatgaac taggagcagt gattaaggtt ataagcatgg
    32461 gacctcctca agctaaaagt gctttaaaag aagctttggc aatgggagct gatgaagctt
    32521 atttaatctc agatagagct tttggtggtt cagatacttg ggctacatct acaattattg
    32581 ctgctgctat agagaaggtt ggaaagtatg atgtaatatt ctgcggaaga caagctatag
    32641 atggagatac agctcaggtt ggaccagagg ttgcagaatt tttagggata ccacaagtta
    32701 cttatgcgaa agaagtaaag gttcaagatg acaaattact agtaactcgt tatacagaga
    32761 caggggatta tttaatagaa gcaaagatgc cagttttatt aactgctata aaagagttaa
    32821 acaatccaag atatccaagt gtcaagggaa tcttagaagc ttataataat ggagatgcaa
    32881 agattactgt attaacactt gcagatttag atgttgatac aactcaaatt ggattaaagg
    32941 gttcacctac aaacgtttat aagtcttttg taccagttaa agacaagcat aatgaaataa
    33001 tagaaggtat aaataaaaaa gaaaaagctg agaaactaat agaaatacta ttcgatttga
    33061 aactagtata ggagtgttaa gatgatgaga gcaaaagtta atcaaggtat aaatttaaat
    33121 gattataatg gtgtttgggt aataggagag caaagggaag gtaaaattaa tcctgttacg
    33181 atagaactta ttggtgaagg aagaaagctt gctgaccaat taggaaaaga gcttgcagtt
    33241 gtgatagctg gatatgaagt agagaaagaa gtgaaggaat tacttcacta tagtgttgat
    33301 aaagtatatt acatcaatga ccctcttctt aaagatttca ctactgatgg atatgcaatt
    33361 tcaattgcaa atttaatcga aagaaaaaag ccagaggttg tattggttgg tgctacttct
    33421 ataggaagag atatagcgcc tagaattgca ggtaaggttg gaacaggtct aactgctgac
    33481 tgtacaaaac ttgaaataga ttcaacagat aataagttat tacaaacaag accagcattt
    33541 ggtggaaatt taatggccac tattgtttgt ccaaaaaata gaccacagat gtcaacagtt
    33601 cgtccaggag ttatggcaaa agctgtaaga aacgaatcag agactggaat tttagaagtt
    33661 gttactccag aacttactga aaaaatgatt agaactagat tagtagagat acttccacaa
    33721 gaaaagaaat ctgtaaatct aactgatgct agaataatag tatcaggggg aagaggatta
    33781 aaaagagcag aaggatttga gcttataaaa gaattggctg ataaattggg ggcagagatt
    33841 ggtgcttcaa gagcagcagt agattcaggg tggatagaac attctcatca agtgggacaa
    33901 acaggaacta ctgttagacc agaactatac attgcatgtg gaatatctgg agcaatacaa
    33961 catttagcag gtatgagtga ttctaaatat atagttgcta taaataaaga tgcaaaagcc
    34021 cctattttta gtatatgtga ctatggaata gtaggagatt tatatgaaat tatacctgaa
    34081 atgatagaat cattaaatag gtaactttta gaaaacattg aatatgtaga atgataagtc
    34141 ttataatatt gtattgtaag acttattatt tttgctgaag gttatagtgg ggagatgaaa
    34201 caatgaaaga gcagtggtat aaggatatat ttgcaagagt attatctatg actgatgatg
    34261 gttttattgt tgtaaataca agtggagtaa taatagatat taatgataaa tattgtgact
    34321 ttttaggaaa agaaagaaaa gatataatag gacaaaatat acaaagtatt ataccaaata
    34381 caaaaatgct agatgttatg aaaaataagt attgtgaaga aggagctata catcattatt
    34441 caggtggaaa tacaaaagaa aaaagtgtaa tagtaagtag gtcttatgtg gaaaatgaca
    34501 atggagaagt agttgcagga gtagctcaag ttaaatttag attgcaatca tttgatgtag
    34561 ctaaaaagtt aatgtcagaa tatatggagc tccaatatta taaagagcag tttaaggata
    34621 actgtggttt tgacaagctc ataggtgaaa atagagactt catagaactt aagaaaacag
    34681 gtgtgaaagc ttctaaaaca aactttccag tacttttaac gggtgaaaca ggcacaggta
    34741 aagaagtttt tgctagagca attcacaata atagcagtag gtcagataaa cctatggtta
    34801 gtataaattg cgctgcaata ccagaagaat tattagagtc agagctattt ggctatgacg
    34861 aaggagcttt tacaggagca aaaaagggtg gtaaaaaagg taaattttta gttgcgaata
    34921 atggtacaat ctttttagac gagataggtg acatgccttt gaccatgcaa gcaaaacttt
    34981 taagagttct tcaggaaagt gagatagaac cagtgggagg tcttaaaact ataaagatag
    35041 atgtaagagt aatctctgcc acaagaaaga atttaagtaa aatggttgaa gagggattat
    35101 ttagagaaga cctatactat agattaaatg taataaacat tcatatgatg gaattgaagg
    35161 acaggcaaga tgatatttta ttgctagcaa attatatatt aaacaaatta aatgttgaat
    35221 acaaggaatt gaaggtttta agtgataagg ttaaaaattg ttttattaac tatacttggc
    35281 cgggaaatat aagagaacta caaaatgtaa taaaaagtgc ctatgctgta agtgatgata
    35341 tggtcattat gatgtgtgac cttccatcta agatggataa tatcagcaga gtagctcaat
    35401 gtaatgtgga tagcaattgt tcaattcatg aaatggttga gaattatgaa aagagcttaa
    35461 ttattgatgt gttaaggaag tataattgga aatgttctaa ggcagcagag gttatgggaa
    35521 tacacaagag tcttttatat aagaaaataa aaaagtatga aattgaatta aataattaag
    35581 ataacttgaa ttaaggcaat gctaaaaaag cgcccttatt caaagcgaac tgtataaact
    35641 gttttatgca gttaaaacgt gtaaaagtag atgtgaagta ctaatgtcaa tcattagtac
    35701 ttttttatta tatttataat tactatctat atttcagtat cttttgatat ctaagattat
    35761 tatgtttaat ttagtatata acaaaaccct cttagttatg gacagttttt tatattttaa
    35821 ctgtctacta agaggggata gtttagttta aatttagagt aaattttatc tagcatttat
    35881 aaaaaatatt ttgaatagct tttttgttat ttagtcataa ttttctactt ctttatcaag
    35941 ttctttgcca caagaatcac acttatatat agcattgtat ccgtaatcat attcatcaac
    36001 tattttcttt tgtctaaata caccaccaca ctcacatagg aaaccaattt ttataagtgt
    36061 aacgataaat tgtgatttta taaattttat atcattgcat ttatcgttag tgtaaaatgt
    36121 ataaatataa gagttatcgc actcatctct taattcaaat ctttcaatat atgtgttatt
    36181 ttttaattcc tcaaattctt ctttagttaa atatgatttt tgttgcaatt catgtaaacg
    36241 cttaatttgg tccattattt atatcctccc aataatttta gtattttaag cttagataag
    36301 gaatctaagt tttattaaat ttatcccaag gaattattta aatcatattt agttttatta
    36361 attacaacat atataaatta cacgaaaata aaactaattg taaaaataat atcctgtgaa
    36421 aacctaaact actaacccct tactaacccg aaaactaaaa aaagaaaata tatccaaata
    36481 taagtgatat ataaataaag atgtttcata taaatttaac tttaaatatt ctgacaataa
    36541 tatatataaa tatattatag ttaaaatata ccacatattt tgggtattgt atactggaat
    36601 tagagtaatt aatttatttt ttaacataca aatgatttta tgaaaaaaaa caagactcaa
    36661 aaatttttat attctttgat agaataaaat tgagagtaaa tttattgaat tttataaaat
    36721 ttataagggg tgagtctaag atatgcatga agataaaaat gatatatttg aatcaataga
    36781 tactgaggat tttgataata aaacagaaga agaatgttta gagctagtaa gaaaaaatgg
    36841 attgaattta atatacataa aaaatcaaac agaagagata tgtctagagg ctgttagaca
    36901 aaattgtaat gcaataaaat gtgttcagaa tcagacagaa aaaatatgta tagaagcagt
    36961 taaacaagat tggagaatgt tagaatttgt ggaagagcca acagaagaaa tttgcatgtt
    37021 ggctattaac caagatggaa cagcattaaa atatatagaa aatcagacag aggagttatg
    37081 cttaagagcc gttgaaaaaa atggtgcagc tttggagtat gtaaaagaac aaacagaaga
    37141 aatatgtata gaagcagtta gaaacagcga atttggattg gcaagagtga aaaatcaaac
    37201 agaaaaaata tgtatggaag cagttaagca ttgtagctat aatctaaaat gggtagaaaa
    37261 tcaaacagaa gaaatatgta tggaagcagt gagacaaaat gggcttgatt tgaaatttgt
    37321 aaaaaatcaa acagaaacaa tctgtttaag agcagtaaga caaaatggaa tggcattaga
    37381 atttgtaaag gaacagactg ttggtatatg cttaaaggca gtaagacaat atggaatggc
    37441 attaaaattt gtaaaggaac aaacagaaga aatttgtaca gaagctataa aacaagataa
    37501 aagagcactt agttttgtaa aaggagataa ggaaaaatat aaggctctat atgataataa
    37561 tgaaccattt gcaaagagat atgttagaaa tgtaatagaa aaagaaaaca gagcattgat
    37621 taaaaaagga gaagaaaatg caaaaatcaa aattgcagga aaactttatg atagaggcat
    37681 gtcttttgaa gatatatcag atatagttga gattgaaata agcaagttaa aagtgagttt
    37741 aggtgttttt taaagtaata aatgtaggtg ttttttatgg gaaatagtta ataaaaaaat
    37801 aatcgactag ctctttgtag gacagcaaaa ttagtgatat aatttgatgt ataataaatt
    37861 atttttatta gataaggggg aattaaagtt gaagattaca gtattatacc aaacaagaag
    37921 tggaaacaca gaaagggtcg ctaagctgat agaagagggc gctaaaaagg tggatggagt
    37981 agatgtaaag cttatgagac ttgataatat tgatttagat tatttaaatg aaagtaaagc
    38041 agtaatattt ggaacaccta cttatttagc aaatacaact tgggaagtaa aaaaatggtt
    38101 tgatgaagat tcaaaaaaag ttaatttagc tggaaaatta ggagctgttt ttgctacatg
    38161 tgattatata tgtggaggtc cagatgttgc gatacttact atagtaggac atttgatggt
    38221 taaagggatg cttgtgtatt ctggaggtgg ttctttagga aagccattta tacatttagg
    38281 acatgtacat tcaattgaag gtccagagtt acaagatgag aaggctataa tatttggtga
    38341 aagaattgct actaaggcaa aagaactatt tgcttaattt ctatatgcat agtaatgatt
    38401 agagtaaatt tagggtttta atggagattt gaagtaaaag ttataaaata aaaaattttc
    38461 cataaaatta ctcaagatga attataatat aattataaat aaattatatt attaaaatat
    38521 ttaaaatcaa acgtcaatag cgagggaagt ttatggtatg gcatatagaa tatgagattt
    38581 tttctgcaat tatagttatt tttttaatgg tatacttttt tagaagtaaa tttataccta
    38641 ctttacaaaa caaaatatat tgtgcacttt taatattctc atttttattt ataatttcaa
    38701 atattttagg ttcattttgt ctaaataata tagacaaaat tccaattttt attacttttt
    38761 tattgaatca gatatactta ttgttattgc caataccagc agcacttgta tcattttatg
    38821 ttatggctat tatttatcaa gatataaggt atatgaaaaa aagattatta tttttatcta
    38881 taccacttat aatttgtata atcttatcta ttacaaatcc ttttacgcat attctatttg
    38941 gattgtcaaa agaaacaggt tatatacgag gttgtggata tgttgcaact tttgcatctt
    39001 ttttctttta tgcaatatat tcagcatttt tatcttttaa atatagaaaa gcaatgcatg
    39061 aatcaaaaat atgggctatt agaggttttc ttatagtttc aattgtggca attatcttac
    39121 aggcaatttt tttacagtat cttcttacag gaactgcatg tgcatgtagt ttacttttga
    39181 catatctttc tatgcagaat cgaggtctta ttattgatga ccttactggt gtactcaata
    39241 gacaatcttt tattcaagag ctagatttga atatcaatac tgaacaatca ggatttatta
    39301 ttacaattgc gcttgatgat tttaagttta tgaatgaaac ttttggaaca aaaaatggag
    39361 atattgcact aaaagaagtt ggaaaatatt tgattcagat acatgatgta aaccatgtat
    39421 atagaatagg gggagatata ttttctattg ttgtcaatag tcaattaggt atagaaccag
    39481 atgatattat cagaaagata gaagaaagat ttaaaaagcc ttggctagta gaagagataa
    39541 gttttaattt agcaactagt attgctgttg tttattaccc agaaaatgca gaaacgacag
    39601 aagatgtaat tgttgctata gatttctcta tacatgaagc aaaacgctct gagtcaaggc
    39661 gagttgttta tgcagatgcg tctataagtg aaaagataaa gaagaaacat gttattaaaa
    39721 attgtttaaa agaagcatta aaaaatgatg ggtttgaagt gtactaccaa cctatatttt
    39781 ctaatagcag gggcaggttt acttcagcag aggcattact taggctagaa cacaaagagt
    39841 taggttttat acctcctgat gaatttattc caattgcaga acaaacagga ttgattaact
    39901 caattggatt agtagtcttt gagaaggtat gtagatttat agctagtgat gagtttgaag
    39961 atttaaaatt ggataatata gctgtgaatc tttctgtagt acaatgtatg caaaaaaact
    40021 tagctgatga tttactttat cttatgaata aatataatgt atcaccaact aaatttaaac
    40081 ttgaaattac tgagactgtg gctatgggct cttttaatat aattaaagaa acaatggaaa
    40141 gattaattga tttaggtgtt aagtttgcac ttgatgattt tggaattgct tattctggag
    40201 ttactaatat gctttcttta ccattttcag taattaagtt agataagagt ttgatttggt
    40261 ctatgaatga agatagtagg cataaactta cagttgagac gattatagca cttataaata
    40321 aattgaatat gaaggctgta gcagaaggtg ttgaaaccat taagtgtgct gaagatttaa
    40381 tagctatgga gtgtgaatat ttgcaagggt attatttttc taaaccagtt ccagaagatg
    40441 tttttaaaaa tttgttgaaa gaaaatactt ttacaagtta acacccttta tttttttaat
    40501 tacaactttg ttcattgaca ctgccagcga tatattataa aattaacaca ataataaata
    40561 ttaaatttat tatacatatt attaatatta attaatggag taaagattta ttatatattt
    40621 tatttaatta tcctaaagtg agaaaggaag atgtgacatg aataaaaaga aaatattagt
    40681 gccaattgat gggacagaaa gaagtatgca ttctttggaa tttataaaag gaatatttaa
    40741 aaaagatgaa gttgaagtag aaataatgaa tgtaaaagaa ctagtattta ttgatggcat
    40801 atccctggct gaagagataa aaaattctga aaatttagga agaagaatct tggataaagc
    40861 agcagagata atgggagagt atgatgttaa agtacatttt acttttggat atccaggaga
    40921 tgagataatt agaaaagcaa aagaagataa tgtagatttt atagttatga caaaatctac
    40981 taaaaaaggt cttacaagaa tgataggttc agtaacagca agtgtagtta aacaagcaaa
    41041 atgtatagtg atgattgtac cggagtagaa ttagaaaggt atttgaaata tgaataaaaa
    41101 gatagtagca gtttgtgaaa gtgaaagaag tttaaattct cttaagacag ctgcaaatga
    41161 tttaggattt gatttagttt atgaaattca agaaaatgat aatataaaaa atgaactttc
    41221 tatttatgat atagaagatg catccatagt gttatttgtt acaagtgatt ctatagaaag
    41281 catagagaag attgatagat ttatagatag agaattttat gaagttgatc caaagtatat
    41341 aatagaggat gcaaaatcta tagtaagtga aattttaata gacttaaatt aatcgtgggt
    41401 gtcgcactaa gaatagagcg acgccttttt atatatttta cacaagaaat aaagaggttg
    41461 tatcaaaata tagataagag tctttttcat tgttgaaatg atgaaaatat atttgatttc
    41521 atacaaaaaa gagtacctca taactaaaaa gttcactttg agacactcca tttttatatg
    41581 ttagttgcat ttaaggtaaa atagaagttt aatcatgttg aaataactga attacatctt
    41641 ctaaatgatt gtacattgat gtataaccta agtaagagtc tttactatca aatgcaatca
    41701 ttatcttgtt atggtggcta atcatatcct tgagagaatt tctatattta aaaccaaagt
    41761 attggttaga agaaactgtt ttaggtatta actcataata ttttataaaa attggattat
    41821 gagaagctaa aattatctct ttgtgaaatt gcaagtcagc atcataacat tcttctatca
    41881 aaccatgaga aaccttatcc aattcctcta ttgactttag gtaagtatat tttatttttt
    41941 gaagttcttt agatgtagca tttaaaattg ctagtttagt agcttcgctt tcgataagtt
    42001 gtcttgctct taaagattct acataaaatt cttgtatgtt atgattttta tagatttcac
    42061 catcatcaaa taggtcaact tttttaaatc cttcaactat aggacttgaa taaggcacag
    42121 ctctaagtat tccttcctta cagagtatat ttatggcatt tcttacaggt attctactta
    42181 tgttaaatag gtcagcaatc tttctctcac ttggtaattt actattaatt ttaaaagttc
    42241 catttagaat gtttaattta atataatcaa taattttttc agtggcattt aagcttttca
    42301 taaaaactcc taaacatata atttttttat gattgtatta tatcatagtt aagagttaaa
    42361 tctacttttt tataatatgt ataagacagg atagaggcca aaatagctat aatagccaag
    42421 ataaagtatc catattgtat tgaagtatat tccgatattt taccaactat cattggaaat
    42481 acagacattc ctatagcata aattgcttga aaaaaaccca ttgcagtaga tttctgatgt
    42541 tttggtacat ttttcataga ctcgctagta aggtaagaaa ggagtatacc tgtagatata
    42601 cctggtagta cttgtagtac aaatattata ttaatatttt ttattgttgg aactaaaaag
    42661 caataggctg aaactaaaat aaaaactaaa ggaatccaaa attttggtcc atacttagta
    42721 caaaatttag tagaagcaaa gccagaagaa gcaacagcac acaccatgta aaatatagaa
    42781 gatagaccta tgagggtaga actagaacct aagtttttaa gaatttgagt agtaaatgac
    42841 attgttgtag acatttgaat accctgttga attaatgcca taaaggaaaa aaatacaagt
    42901 cttttatcct tgcagataga taaatatttt ttaattgata ttttttcagg tattttttta
    42961 gaattatgat tttttatatt taaggctaga atcgttccaa taactgaaga caatacactc
    43021 atgatacata aggctgtcat tcctaatttt tcataaaata aagtactcat aacaaatcca
    43081 atcaacattc ctagattgtt taccaatatt atcgtacttg tagctttttg ttgatgttct
    43141 gtagaaaaaa agttggtata gtgaaccatg taagaaatcc aagttgatga tgatattcca
    43201 gataaaatgt tagctataag aaaaccattg cctccaggag aaaagactct tataagagat
    43261 gctaaaccag caaagaaaat tccagacagt ataaatattt tatgtttatt tatggaatca
    43321 gcaaatactc caacaggaag ccttaataaa cattgtgata ttccatatgc acctattatt
    43381 ataccaatca tatttgtaga tacattacat gcacttaaat atggattttg gaaaggtata
    43441 tatacatatt gtgaaaacca gaaaaatgta acaatagaaa gtaaaagtaa tttttgatta
    43501 gatatttttt tcatattatc ctccatgtgg tatttttata atgcaaataa tataccattt
    43561 agatttttta atcaagtact ttctctatta aaaaaaattt aaatatataa ttattattta
    43621 caaaaaaatt atactttata gttgaattaa gaaaacgctt atgatactat aaagttaaca
    43681 aatttgaata tataacagta gacgtgttac tggtaatgca ggcaagatcg aatcaatttt
    43741 tatagattat ctatagagta ctatgggtat aatctattta tttggttcga tttttttgtt
    43801 taattggcca taaaacaaaa agcctatagt tgaaaatgga ggatttttta tggattataa
    43861 aaatatagct caagaaattc tactaaatgt aggaggaaaa gagaatgtaa atgaagtgac
    43921 tcattgtatg acaagactta gatttaaagt caaaagcgct tctaaagtga ataaggataa
    43981 attatctaaa actgaaggag taataactgt tgttgagagt atgggtcaaa tacaagttgt
    44041 aattggaaat aaagtaaaaa aagtatatga tgaggtcata aaaattgtac ctcaatcaaa
    44101 taacataggt aaaaagaatg aaagtcaaga aaagcaaggt ataattaatt ctatattatc
    44161 agcagtagct ggtatattta cacctacaat acctgctata gcaggggttg gtatgattaa
    44221 aggtatttta tcagttcttg ctatgtatta tatgaataaa aatggagtag atataaaaga
    44281 aacgcaaagc tatattatct taaatgctat ggctgattct atattctatt ttatgcctat
    44341 tatactagga tatactgcgg ctaaagtatt taatgcaaat aaaataatat ctatggtatt
    44401 aggagctaca ctttgttatc caacttttac tgctttgatg gcaggtgaag aatctgttag
    44461 atttttagga ttggcagtaa caaaagctac gtatacatca tctgttattc caataattat
    44521 tgctatatgg gctctttcat acgttgaaaa agtattagaa aagtatatac ctgaggtaat
    44581 taaaataata atggttccaa ctttatcatt ggtagtaatg ttacctgcaa cattattttt
    44641 atttggacca atcggaattt atataggaaa tgtcataaac ttttcttata agtatattta
    44701 tgaattaagc ccagcattgt gtggagcatt tgtaggtggg ttatggtgtg tgttagttat
    44761 atttggtgct catagagcat tattaccaat aggtataagt gatgttgctc aaacaggaag
    44821 acaaaattta ttggcgtttg caggagctgc aaacttttca caagcagggg ctgctctagg
    44881 agtattcttt aaaactaaaa atcaaggact aaaaacaatt tctatgtctg caactataac
    44941 agctttattt ggtataactg aacctgcaat atacggtgcc aatcttagat taaaaaaacc
    45001 tatggtatgt gccgtaatat gtggtgcatt tggaggtgcg ataatgggaa tgggtggagc
    45061 ttatggtaat gcatttgcaa accaaggtgt tttaactata cctgtatatg ctgaagcagg
    45121 tgcattaggt ttcttaagtt atctaggtgg ttgtgctata gcattttttg gttcagctat
    45181 ttcaacttat ctagttggat ttgaagattt ggaagagtct tctaataagg aaaattcatc
    45241 tataaaagta gaaacgaagg atggtgttat tgatataact tcacctgtag agggcgaatg
    45301 tatagaattg tcagaagtaa aggatgatgt atttgcttca aaagctatgg gagaaggtat
    45361 agctgtgtta cctacaaaag gagtaataac agcccctact gattgtgaag tagcttcttt
    45421 atttccaaca ttacatgcaa taggattaaa attagataat ggagcagaaa tgttaataca
    45481 tgttggaatc aatacagtag agttaaatgg taaatacttt acaaaacatg ttaatcaagg
    45541 agatttagtg aaaaaaggtg ataaacttat atcctttgat atagataaaa taaaaaaggc
    45601 tggttatgat gtaactacgc cagttatagt aaacaataca tttgattaaa aaatagctac
    45661 gcacactcgt gactttagtc atgagttagt agctaaaata gtcagcatat agggaaacct
    45721 atatgtagag ataggataga acctatccaa tactacttga attgctggaa acccctaaag
    45781 ctaaccaaac taaaacataa ggatgaaata aacctaagtg tgaaagttac gaaagtagaa
    45841 aaaattggtt agatggtata aggttaaatc ctaagtactt taaaatgggc aatcagcagg
    45901 taaactccga ataggagaaa cttcaacgac tattcctctt gagggaagta cactacaagt
    45961 tatcggtagt ggaagtgggt agaccttaac ggataatgcc gaaggataag atatagtctg
    46021 tgctt
//
LOCUS       DAMKNB010000027        45073 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.028, whole genome shotgun sequence.
ACCESSION   DAMKNB010000027 DAMKNB010000000
VERSION     DAMKNB010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 45073)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 45073)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..45073
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.028"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            complement(112..798)
                     /locus_tag="PC494_001649"
     CDS             complement(112..798)
                     /locus_tag="PC494_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF3912153.1"
                     /translation="MKITHNSLAVEAKNIIKEYKIGNTTTRVLKDVSLQVMKGEFVSI
                     MGQSGSGKSTLLYILGGLDTPTSGKVYMNGADISHFNDEKMSIIRRRNIGFVFQFYNL
                     IPNLNVEENIMLPLLLDGKNLKDYKNQLDEILDIVGLTDRRKHTPRELSGGQQQRVAI
                     ARALIGKPEILFADEPTGNLDSKTGIEIIDLLNKINRDNGQTIIMVTHSPEAAKSSSR
                     TIIVSDGLIV"
     gene            complement(813..3290)
                     /locus_tag="PC494_001650"
     CDS             complement(813..3290)
                     /locus_tag="PC494_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HDF3912154.1"
                     /translation="MKIILKYIFTNIKERKIRTAVMLLSIVLSTVLLFVSFSIGLSYE
                     SAQRKMAKGMYGTATISVQSKNPDILTNLEDIPDLNTIKSKVGVLESSAIYNKGGYYE
                     EFSLISADLSQLNKINKPRLENGDSITDFSGDKIILPNRFTSKYKIKKGDSITLQIYG
                     KSYTFQVSDIASYDTVFLRNTRGVNALLPKETLSKIINKGSGYTRVLIESEEEITENL
                     VNKLSEELSTEKYMVSNTINETKIISDARQKTMPFFLISFFALTLSIFIIYSSYKVIT
                     LERLPFIGTFRSIGANEKTVTRILMLESILYGSIGGLIAIPIGVVVLNLMLHGLGNSL
                     EQGISIPVVISPIGVIISVIVAIIVSSFSAYIPVKKASHLPIKNIVLGTVEEKNVSNR
                     SILFIGSIMFILSILLPRISPENTLYLAGGFSLLGLIVATIVLIPLITDIMSIVFEFV
                     YKNILGNEGKLAARNMKNNKNIIQNITLLFISISAVIAISVVGNFVKTYITDVFRDAE
                     LQGFADGKMNEEFIEDVRHMDGIKKILPLYVMNNEISGNGVTLSRLEGTDNIKLYNSM
                     FGINYTNFEIKKQVIEAFNDKRSVILNEDTLKKVGLSIGDTITLSNDKYDFSYKIVGS
                     FKSRANDVEAVIPSHYAVNDFDKTNYGFLVYTAVNPDAVMIQIRYLFGDTYNWSRTVE
                     EFNNDSLNTISSFLSPMNKMTYFIFLLATVGIINNLLINYIQKRRSIAMYKSIGLSDK
                     QNIKVTLIEGFTSGLLGAVIGIVISILEIQTIFIVAGPKISMKPDLDFKTFIIVGLLG
                     IIVTLIGSIVPIIKGKKMKLIEEIKFE"
     gene            complement(3509..4912)
                     /locus_tag="PC494_001651"
     CDS             complement(3509..4912)
                     /locus_tag="PC494_001651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF3912155.1"
                     /translation="MHKPSYKTVFHSYIIFFMIFICLILTVIGIFLSLITIQKPNGEF
                     IRSDWPKKFTENFNEQIVFIDNKPQVKQSGLEKLRENQLWLQILDSSGNRVYGFLEPK
                     EHKDYYSNSELLALANQNNSSNGTVYFNTIKNNKNDYIYIIYFPLNISKVNMFFDGGK
                     FIGGKSIVFSIIGIIFLIILVSGIAYGYWVTKCISNITSAVSDISKRSYLPVNIKGVF
                     ADIYNSLNILNEEIHKSDEIQNKTDIMREEWISNITHDLKTPLSPIKGYAELLTDSST
                     NYSPEKVYKYASIMLKNIEYTNTLINDLKLTYQLKNGIIPLNKNNYDLVRFLKELSID
                     ILNYPEYESKIVEFKSNIDNINFDFDCTLLKRAFSNLIVNAFTYGYKNTKVCVHITLN
                     ERIEIIISDNGKGMSREEASNLFNRYYRGSNTKQKIEGTGLGLAITKQIIEVHGGNIS
                     VESIPGLGSSFYITFPI"
     gene            5410..6270
                     /locus_tag="PC494_001652"
     CDS             5410..6270
                     /locus_tag="PC494_001652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HDF3912156.1"
                     /translation="MKKQKSPILLEMLGLFFGCISMSIGINMFLKPHTIAPGGLSGLS
                     LVLNKVTGLPVSAIMLIIGVPLVILAFRIMGTKNSLKTLFGTVVFSAIVQLTDPLSKL
                     RFTNDLLLSSIAGGILVGIGLGIMFKSDASTGGTDLIALILSKKFPGIKATKFMSCLD
                     GMVVISSGIVNRSLETALYSGIALCVLIKIADMIMEGFDHSKAFFIISDEPESLRQAI
                     TEELDRGLTILDGKGGYTRENKEVLLVVVSKKQELYLKRLVKRTDPTAFVIVTDVHEV
                     LGEGFKNLEN"
     gene            complement(6509..7066)
                     /locus_tag="PC494_001653"
     CDS             complement(6509..7066)
                     /locus_tag="PC494_001653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDF3912157.1"
                     /translation="MSDSEYPQMKTLETRSCILRPASLDDVEDFFDCYKNKIVVKHLP
                     FSEHKSLEDTRKFIKSFFLNPYKKGKIGHFAIVYKRDNKVIGNMGFNNINPKALEAEI
                     GICINPSYWGHDFATEITKRVIQYGFRELNLNKIIAITYEENQNSKKSLDLLGFKCTG
                     KYIKKIHTGNTVKNVPCYQYELKKQ"
     gene            complement(7256..8143)
                     /locus_tag="PC494_001654"
     CDS             complement(7256..8143)
                     /locus_tag="PC494_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDF3912158.1"
                     /translation="MNIKLELYKVFNAVVNNKSFSLAAKELFMSQPAVSQSIKQLEEQ
                     LDTLLFYRNNKGVKLTPEGKILSEHVTTALKLISSGEDRINKFKKLEYGSLKIGVGDT
                     AARFFLLKYLEIFHKKYPHIHVSTINRTSRELISLLKDGNIDIAIINMPIEDDTLNIV
                     ECIEIHDIFVCANDYIEYKGRKISLEELNTLPLIMLENKANSRLYVNEYFLSKGIKLN
                     PDIELGSHELLLEFAYINLGVSCVIEEFSIDYLENEKLFKLDIKEPIPKRNIGYCHLK
                     DISLSLATKEFLSMISNNI"
     gene            8262..9461
                     /locus_tag="PC494_001655"
     CDS             8262..9461
                     /locus_tag="PC494_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003493023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="coenzyme F420-0:L-glutamate ligase"
                     /protein_id="HDF3912159.1"
                     /translation="MDRLVGTVSRGVRAPIIRQGDDLVKIVVDSVLNASKSENFEVRD
                     KDVIAVTEAVVARAQGNYAHVDNIAKDVKDKFGDDTVGVIFPILSRNRFAICLKGIAK
                     GCRKVVLMLSYPSDEVGNHLISIDELDDKGINPWSDVLTEEKYRELFGYNKHTFTGVD
                     YVDYYKNLIKDCGAEVEIVFANNPKTILNYTTSILTCDIHTRQRTKRILRQNGAKKVY
                     SLDDIMTASVDGSGYNDQYGLLGSNKATEETVKLFPINCDEVVNKIQGNIKEITGKDV
                     EVMVYGDGAFKDPVGKIWELADPVVSPAYTKGLEGTPNEVKLKYLADNDFADLSGDEL
                     KEAISKYIVEKDNKSDDLTGNMVSQGTTPRRLTDLIGSLADLTSGSGDKGTPIIYIQG
                     YFDNYTK"
     gene            complement(9655..12210)
                     /locus_tag="PC494_001656"
     CDS             complement(9655..12210)
                     /locus_tag="PC494_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HDF3912160.1"
                     /translation="MMSLVKFSIQYIKHYKKQSISIVLSIVLSVALLTGIGSLVHSAD
                     KSRIEKIREDSGDYHYFYKVDKEQLNKIKENKKSKEYTVDRLGITKPKNQIDEPFIIE
                     FLNADSSYLDMTGRKLLKGTLPSKDGEIVLDTYSLNNLNVNKEIGTEINLDGKIYKLC
                     GILSSLSNPETALEGFVNDYFQPKEKDSYIVYVKYDENKNIKKQNYKFMKKFNISKEK
                     TYINWPLSVEFGVKPPKNIEKYNIFEFLKNLELNTNAIILLVGVFGAAAVYSIFHVSI
                     LQRISQYGVLEVLGANNKQLLFLLFLELFLLFIVGFPIGCFLGIEVASTIYEQFPHIF
                     LSSDIVPGAFFISEKSIYLGFLFILLLLILIAVRVVHQLNKYSSIESMKNFKITNKKK
                     RILESVKHSNMTKVLSHKYMTQKKGMFIGILFSLSLGGIIFLCSSYSIQLTKNNNELT
                     MKADDGLNSDYQITMQTTDFDVGIPKDKISRLNNVEGISKVYPVRYLFGAMQIKEEQL
                     FWKNFFKPLEKDYRIKTFFDGICTKQNEGGYLLKTNIYGYNNGMLEGLNSYIIDGEIN
                     THDMVKNNKVIVRLPMDGTGMYDAVDINPGDTIKVKVPKTMKPTDEIVKFKEENKNDY
                     TTKEFVVAATVKRVMANNIYFIGDYGMDIVMTNGQMKNNFDIENYNSVSIKKTEDSNS
                     EELSENIKSVVSDVKRCIVTDYTIAIEKNNTYLNQKLLFIYGIVFVLLAISLFHIINT
                     VSYLIFSRRHEFGILRAMGITDNKFLLMMIREGFLYGFYASIIMVIGSVIGQFMIYFM
                     VKRVYLYINPILKINTPLYIGMIILNITISIVAVIIPVRQILKSDIISEINKN"
     gene            complement(12207..12893)
                     /locus_tag="PC494_001657"
     CDS             complement(12207..12893)
                     /locus_tag="PC494_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF3912161.1"
                     /translation="MSILVTNNLVKHYGKGETKVKALNGVSIEIERDTFTAIVGTSGS
                     GKSTLLNIIGGLDNPTSGDVIIKGKNISKIGKKDLTVFRRRNIGFIFQNYSLMPVLNT
                     YDNIALPVTLDKGNHIDHEYIEMLMKTLGIWDKRLKFPSELSGGQQQRVAIARALANK
                     PALILADEPTGNLDSKTTMEVVCLLKESSAKFHQTILMVTHNENIAQVCDSIIHIEDG
                     VVVNTGGEVL"
     gene            complement(12970..13878)
                     /locus_tag="PC494_001658"
     CDS             complement(12970..13878)
                     /locus_tag="PC494_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF3912162.1"
                     /translation="MFILAFIICTVVIFIVSTKINRKRYDELNLMLNQILEGKEVTYP
                     DTKDTRASKISHQVKKIKDMIEIEVEQSKSEKEAIKGLISNMSHQLKTPLSNITIYCE
                     LLENINISTLQKKEFLQKMKNETFKIDWLLQSLFKMTKLEDGVIEFEVEELLIKDTLI
                     QSISTIFNKAEAKNIRINLEPFSDIKLVHNKKWTIEAIVNVLENAIKYSPSDSTITIS
                     VIKMELYTKITIKDEGIGIDSRELNDIFKRFYRSKNVENQNGTGIGLYLTRLILEKEN
                     GNIIVESKLGSGCCFSIFLQNCKSLN"
     gene            complement(13880..14551)
                     /locus_tag="PC494_001659"
     CDS             complement(13880..14551)
                     /locus_tag="PC494_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF3912163.1"
                     /translation="MNLLIIEDDINLNEGLFYAFENDGFNVFKAYTKQEGLNIFNSKN
                     IDFIILDCNLPDGYGFDVCQIIREKSDIPIIMLTARDSEIDEVKGLEIGLDDYITKPF
                     SLSVLKARVKVAIRKKSNNKVIYSNGIKLDQKLLKVYKNKECLELSSVEYKLLSYLIE
                     NKGQILLKEQILHHIWDSEENYVDDNIVSVNIRRLRVKVEDDPSNPKYIKTAYGMGYL
                     WNEVE"
     gene            14813..15877
                     /locus_tag="PC494_001660"
     CDS             14813..15877
                     /locus_tag="PC494_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S ferredoxin"
                     /protein_id="HDF3912164.1"
                     /translation="MKRVDERNTMFARANYKKDSTAYNDYYKKNPDKKEIDDSIRNRP
                     NLCSEGTMTYNELNSPMASSAFDFLSDIKSLCEGKVSDTKVDVDAKSMTKKIKGLAKQ
                     YGASVVGITKLKDYHIYTNRGRHEENYGEEINLTHKYAIVFGCEMDKEMINRAPMICE
                     VIETSKCYVDASIVGMILSYYIRNLGYDARNHMDANYLVMPVFIARDAGLGDIGRNAI
                     LTNKDYGSRLRLGVVTTDIPLLEDEYVDFGLEDFCKVCKKCSFNCPSHSLSNDIKIGD
                     DGKYNWVIEHETCYIKWRYLGTDCGMCISACPFSQNLETIKNTTSFKGNNELIQKALD
                     EYTSKFGKRIFIPGNPSWLK"
     gene            16035..16721
                     /locus_tag="PC494_001661"
     CDS             16035..16721
                     /locus_tag="PC494_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF3912165.1"
                     /translation="MEKILVVEDDSILNKTLSYNLIEDGYIITSKFTAKSALKSIFEC
                     EFDLIILDINLPDKSGFELCNEIKGNYNIPIIFLTANDMECDMIKGYELGALDYITKP
                     FNINIFKQKVKAFLNHLTIKTKQDYYRDGYLEINFSELSANINGNQIIFTPLEYRTLK
                     LLTENPKSILTRKVLLEKLWDIDANFVDEHTLTSVISRIRSKIEKDNLKYIKTVYGMG
                     YMWLGERNEF"
     gene            16711..17742
                     /locus_tag="PC494_001662"
     CDS             16711..17742
                     /locus_tag="PC494_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF3912166.1"
                     /translation="MNFKKFSFSSIYLIIAVGIIFTAILFSISIYLITADLKLIALLL
                     IYTIVLCGFIALIIFLLHKKIVIFCSKICHTLDSMMNSEDNIEIELEEETILSRINHR
                     LIRMYEVIQENRNSIAIEKADLQELVSDISHQIKTPIANLKMINTTLLNQTFKTEIQK
                     DFLMDMENQLDKLDFLMQSMVKTSRLETGIITLSKKKNSIYETIATALSGILFDAEKK
                     NIEVTVDCDPNLYIIHDKKWTSEAIFNILDNAVKYTNSNGKIRVATECWVMYTKIDII
                     DNGKGISESHQAEIFKRFYREEDVHDIEGIGIGLYLSRKIISLQGGYIKVTSDIGKGS
                     TFSIFLPNK"
     gene            17824..18489
                     /locus_tag="PC494_001663"
     CDS             17824..18489
                     /locus_tag="PC494_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF3912167.1"
                     /translation="MSILQVINLKKYYGQSSNITKALDGVTLSIEKGEFISIVGTSGS
                     GKSTLLNMMGGLDNPTSGKVIIKGKELSTMTDEQLTIFRRRNIGFIFQNYNLVPLLNV
                     YENIILPIGLDGETIDKDFINEIINMLSLEEKLYDMPSNLSGGQQQRVAIARALVTKP
                     AIILADEPTGNLDSRTSSDVLSLLKVTSKKFNQTIVMITHNNEIAQLTDRIIRIEDGK
                     IVN"
     gene            18502..20919
                     /locus_tag="PC494_001664"
     CDS             18502..20919
                     /locus_tag="PC494_001664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF3912168.1"
                     /translation="MFRNNNRTFIRKIALNDLKINKLKTYLSGIIIMISTCLLLTVTL
                     VSYNASVDLVNASPYHAIYKSVDEKAKNILYKNKNFSGVGTYKLIGSNKKTDCIMSIV
                     YADDTTIKLMNFQPLKGKLPTNKNEIAISEKYLQEFGLDKDIGDSIKLNYYDDITNKE
                     VQCDFIIVGFLENYYQDNAKQYYTVVSNDYFKNIASTPLQNKSNTFDESRPDTVDVLV
                     KLSEENTEKDSASIKTQLKKIGLSLGIKKYNIYLNDNYIESNLIDGEQIITVLVVGIV
                     VLFSSVFVIYSIFYISVVNLVQMYAKLKSLGMTSFQLKKIIFLQGNILSIIFIPLGVI
                     ASCIIAYIIQPLAWQMIADLFIILILSLVMFLTVRISLFKPARIISKISAIEAMQYTE
                     TKFRKKVKNFSYINIKNLALKNIESNRKKNLIALISLSISGVLFISIANLANSIDFKK
                     QLSQQFVYNEDYIISIKSDNLYEHITEIQQNNPLTDSLKNEIKSIHGVKKLIESKLIK
                     SNIIEPYIKDRDEKQFITLIKGITPELSKSLEEYIVSGKIDYTHLDSDSLIINKYRTK
                     YYGLNLKVGDTVTFNIFSGNDIIKKKMKIIGIIDNSNTEGMFFASDKTLESLTPYNTN
                     LDFSILIDKKYSKEVEEKLLSIIQKNSNLMLYSYEDDYRMITRAFQYIIIASYIFVGL
                     ISCFGILNMTNTLINSVLIRKKEFALLQAVGMTRKQLRNMLYREGLNISIKAICTSSI
                     LGYFGSNLLCTFIKDVIRLDFINFKFSIFTILIFSFVLIGIQVLVTELLVRNIEKKSL
                     TERLRSQ"
     gene            complement(21100..21891)
                     /locus_tag="PC494_001665"
     CDS             complement(21100..21891)
                     /locus_tag="PC494_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HDF3912169.1"
                     /translation="METKQYLIDFYNTYDEDSRLALKHGMVEFLTTMHYIDKYIKSGD
                     CVLEIGAATGRYSHTLARQGYDVDAVELVEHNIEVFHKNTQSNENISITQGNAMDLSV
                     FPDNKYDITLLLGPLYHLYNKEDKQQALHEAIRVTKPGGVVFAAYVISDGCLIDEGFH
                     RGNINVSEYIEKGLIDPQTFAAKSEPKDLFELVRKENIDDLMSAFNVTRLHYVASDGL
                     ALYMREAVDSMDDDAFALYLKYHLATCEREDLVGVTSHAIDIFRK"
     gene            complement(21924..22511)
                     /locus_tag="PC494_001666"
     CDS             complement(21924..22511)
                     /locus_tag="PC494_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDF3912170.1"
                     /translation="MPPKVKITKEMILNTVLDITREVGFEAVNARSIASKLQCSTRPI
                     FTCYENMNELKNEFLAFAYEYYNQYVVNYRNSKSVSPYLLLPLSYIEFAQEETYLFKL
                     LFINDLDLMMKEANDFYKEIDNEKKARLFSESIGIELECAKVIFLDLFLYTHGIAVLT
                     ATKKLTLDRYSAEKMLKNILTAFIRQEKPDWNLSI"
     gene            complement(22687..24078)
                     /locus_tag="PC494_001667"
     CDS             complement(22687..24078)
                     /locus_tag="PC494_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="benzoate/H(+) symporter BenE family transporter"
                     /protein_id="HDF3912171.1"
                     /translation="MERLARREQPHIKFGMFKIRIPFIHYRFEKPEAIQGIISSMTSL
                     GTIGLSTQILGLPYEVAWSMAIINSILYCLHVFMGDPVVPGWITASITLTTAYLLKFS
                     MGIERIQALTALQIDLGIIFILMGITGVAGKLVSKIPNSIKGGILMGVGISTIISEFN
                     PKGRFDSYPISITVGILVACFVMFSERFDTLKVKNKFLFHLGEYGVVSAILVSLIVGI
                     FSREIEIPRFSFDNLVYIVDFKNLINTVSPFGIGFPSVMLFIQGIPMAFMIYIIAFGD
                     FITGENLVLSESENRKDEYIDFNSNRSNVISGIRNIFMAIFSPYIPMCGPLAATLTGS
                     VAQRYKIGKEAMQSVFSGMGTLVWVSAIFICFYPIAQIATPLIPLALSVTLLVQGYLC
                     TKLSMELCNTGVEKGLIGLMGGVIAAKGGTWGLAVGFILYFILIDSKKRKEKDINSIE
                     DCVYEILDKKKSI"
     gene            complement(24268..25566)
                     /locus_tag="PC494_001668"
     CDS             complement(24268..25566)
                     /locus_tag="PC494_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA thioesterase/BAAT N-terminal
                     domain-containing protein"
                     /protein_id="HDF3912172.1"
                     /translation="MKVNVYNVESFVDERLKIMVSDLIPNTKLKISVKMEFPWCKGEE
                     FSSYGVFCSNEKGEVDLDLVEPIEGTYKADNCMGLIYSLEKSKTEGKNFAENISIDKP
                     IIMNMIFETSIERKEVELKRIFKSEDITTKYISDEFIGKLFYKQNSNNKTILMLGGSD
                     GNLDALDLLAAPLASRGFNVLTVAYFALEGLPDKLEEVPLEYFEKVFEWISENEITST
                     KEIFVHGTSKGGELAFLLASRYEQIKKVVVSQPHIYCFQALNGLMSGNDTSSWSYKGE
                     PFPYIKVDNDIFFEEQKKNISKDIPFGFNSTYKKSLKRAENRKEARIKIENSKADILM
                     IAGKEDNIWNSYEACLEALEIFEENNYPYNVELLTYNNMGHPLPIPYIMPLKETLCMS
                     MSGGIFSSGGTVEGNSKGQFESWNRTIEFYKKPLSSDLNN"
     gene            complement(25925..26800)
                     /locus_tag="PC494_001669"
     CDS             complement(25925..26800)
                     /locus_tag="PC494_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kinase"
                     /protein_id="HDF3912173.1"
                     /translation="MITFDVNGAIIRFDDTKNNYNKIRKIFKLYALEISKNFERDCLN
                     SFQNLKQISDRGLSLGEKYIEESFKKGIETIVSFGIITIDIDTFKSVYCEKYLDFKRL
                     FNNLNKTFIIPNKNKKNGHASFLEIESTIKKMSNYLYNDCFKIHYAVVDALIENRITA
                     VHSYIDEESIKKSNALFNNYKDGFIGKADECKVVKQIITLNPYREDVYEFLVKEDGDF
                     SKEIERLTEFLGYDIREYKASLMDIYINELMESDENDVENAKEKIEKYARYIGCSDEN
                     LYVARVNAIYTFANA"
     gene            complement(26993..27679)
                     /locus_tag="PC494_001670"
     CDS             complement(26993..27679)
                     /locus_tag="PC494_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF554 domain-containing protein"
                     /protein_id="HDF3912174.1"
                     /translation="MFGVIANSLAIAGGCIVGLIIKGGLPQRVSDTIMNGIALCVLYI
                     GISGALEGKNTLVTIISVAVGALIGELIDIDKWVNKLGAFLQSKFSKGNKKDSIAEGF
                     ISSSLLFCIGAMAVVGSLESGLTGSHDTLFVKSVIDGIASIIFTASLGIGVMFSAISV
                     FLYEGIICVGASFLNGFLSDPVVTEMTAAGSLLIIGLGLNVLKLTNIKVANLLPAIFI
                     PILFGVFGII"
     gene            complement(27728..28261)
                     /locus_tag="PC494_001671"
     CDS             complement(27728..28261)
                     /locus_tag="PC494_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA synthetase associated
                     domain-containing protein"
                     /protein_id="HDF3912175.1"
                     /translation="MSDLNNKKEQDENESSMNETKIYDILDKLNVEYDVVEHEAVYTA
                     EQLVILDGITKGCQCKNLFLRNAKGNKYYLIVVKGEKQVDLNSLKDKIGSSRLSFASP
                     ERLYNVLKLLPGSVNPFSLINDTERKVELYIDKDVIKEDYLNFHPNINTKTVNISRKG
                     FEEFLEYLKYPIQSIDV"
     gene            complement(28305..28937)
                     /locus_tag="PC494_001672"
     CDS             complement(28305..28937)
                     /locus_tag="PC494_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclase family protein"
                     /protein_id="HDF3912176.1"
                     /translation="MKVFDLTHVTHNDMPVYAEPNRPDIKKVAIIEENGYQETLISVF
                     SHNGTHMDSPRHMYTKGETLDKLDIENFVGKAYVLELEKGNENIELEYLKKYEDEIKN
                     SDFIIFKSGWSKFWDKKQYYVGYPTLTKEAANYIANTNIKGIGIDMLSVDRYDTSVFE
                     VHHILFEKGKIIIENLTNLENVPEKFLFIAAPFKYNDADGAPVRAIAIVE"
     gene            complement(29027..30106)
                     /locus_tag="PC494_001673"
     CDS             complement(29027..30106)
                     /locus_tag="PC494_001673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIR2 family protein"
                     /protein_id="HDF3912177.1"
                     /translation="MKIAIFLGAGASAAENLPIQNELFSEYFKKLNPTNYNTKMNREL
                     YIFFKQMFNIDIVKDNIDNANFPTFEEVLGLLDLAEQRKEAFRNFGLENLNNRSDSIR
                     FLRQYLILLMAEAIHNTPRTDNKYHKLLVENLLENDLLLDTTFISANYDIHIDNTVTG
                     LRDKNDLPIMLDYGVEFTNFKEELNWRKPKEPLIKLYKIHGSLNWLYCPICNSVTLTP
                     HEGGVMKLIENSSETKCLECGELTEPIIVPPTYFKNMSNIFLSNVWNETEKTLRDTDL
                     LIFCGYSFPEADMHIKYMLKRVQTNRKKPPLKIMVFNNHSQKQRITLKKEEGRYKRFL
                     GEDVIFTDNSFQDFSVNPLRFIKNI"
     gene            complement(30239..31585)
                     /gene="pepV"
                     /locus_tag="PC494_001674"
     CDS             complement(30239..31585)
                     /gene="pepV"
                     /locus_tag="PC494_001674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HDF3912178.1"
                     /translation="MKEQIKEKVNSLQDEMISSIQESVKIPSVISEATENCPFGENVD
                     KALRGILDLCKSLGFKTVYKDGYYGYAEIGQGEKMIGILGHVDVVPEGDLESWNYPPF
                     EAVLEDGKLYGRGTQDDKGPTISAIYAVKALMDLNVDFNKRIRFIFGADEENLWRCIN
                     KYKENNEEIPNYGFTPDSRFPITNAEKGLLQVHLTCDSKSDIELSVGKALNAVPGKAI
                     YIGKYSDKLKKELDKLNFEYTVEGNKICIIGKSVHSAASDTGINAVARLCIALNNIGI
                     DSNIIKFLAEVIGEDANGNNIIPNCKDDVSGKLTVNIGRVTIDNEKEFAGIDVRIPVT
                     YKKDDFVKELKKMTDKYNLNYEEYDFLDSIYVPEDTLLVKTLRKVYEEETGLDGTPLS
                     SGGATYARALDNCVAFGAIFPGKPETEHQANEYLIVEDIIKATQIYALSIYELLKI"
     gene            complement(31654..32934)
                     /locus_tag="PC494_001675"
     CDS             complement(31654..32934)
                     /locus_tag="PC494_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine gamma-lyase family protein"
                     /protein_id="HDF3912179.1"
                     /translation="MLNETKELLKDYYGIDDDTFKLSQEIMEEIKDKFEEIKEIREYN
                     QYKVLKAMQESKLSDMHFNWTTGYGYNDIGREKIEEIYSKVFNTEDALVRPIIVNGTH
                     ALTLCIQGIVRPGDEILSVTGRPYDTLEGVIGIREEKGSLKEYGVTYDDVDFLEDGNL
                     DLEGIKSKINDRTKLVMIQRSKGYSWRKSLSISDIKEAIEVIKSVKPEAIVMVDNCYG
                     EFLDTKEPTDVGADVMAGSLIKNPGGGLALTGGYIAGRKDLIELISYRMTSPGIGKEC
                     GLTFGTTRNVLQGFFLAPYIVSQAVMGAIFCSRAFEKLGYDVLPKYDDLRSDIIQCIR
                     LNNADEVISFCEGIQEAAPVDSYVKPVPWDMPGYESEVIMAAGAFIQGSSIELSADAP
                     IRPPYNVYFQGGLTFDHSKMGTLKAIEFIKKLKK"
     gene            complement(33061..33321)
                     /gene="hfq"
                     /locus_tag="PC494_001676"
     CDS             complement(33061..33321)
                     /gene="hfq"
                     /locus_tag="PC494_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA chaperone Hfq"
                     /protein_id="HDF3912180.1"
                     /translation="MKNTVLNLQDLFLNNARKERIPVTIYLVNGVQVKGLVKGFDSYI
                     ILIEGDNRQQNMIYKHAVSTIQPGKYINLTNQNQNNNNNNNR"
     gene            complement(33435..34370)
                     /gene="miaA"
                     /locus_tag="PC494_001677"
     CDS             complement(33435..34370)
                     /gene="miaA"
                     /locus_tag="PC494_001677"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HDF3912181.1"
                     /translation="MKKIPLIILTGPTAVGKTDLSIKLAKDMNAEIISADSMQIYEYM
                     DIGSAKVTEEEMQGVKHYLIDEVKPDYPFSVSEFQQRAKKYIHEINEKEKCVLVTGGT
                     GLYLNSLIYNMDFAQSDANNELREELQKQLAEKGIDYMHNKLKELDEESANRIHKNNT
                     KRVIRALEVCLSGKKMNDFSSDLKFNEEYQPIIIVLNRDREHLYQRINMRVDIMIKNG
                     LVEEAKKLLSMGFKKDMISMQGIGYKEILKYLDGEYTYEEAIEIIKRDSRRYAKRQIT
                     WFKRYKTAKWFDLDQYENIDELKNEIILYIKDSIK"
     gene            complement(34408..36375)
                     /gene="mutL"
                     /locus_tag="PC494_001678"
     CDS             complement(34408..36375)
                     /gene="mutL"
                     /locus_tag="PC494_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HDF3912182.1"
                     /translation="MKNIINILDDLTINKIAAGEVVERPSSVVKELIENSIDAGANKI
                     SIDIIDGGKSLIKITDNGIGIPSSEVEKSFLRHATSKIKKIDDLYDLYSLGFRGEALA
                     SISAVSKLEMTTKTKDEIIGTKIYVEGGKIISKEPIGSTNGTTIIIKDIFFNTPARQK
                     FLKSTHAETINISDLINKLAIGNPNIQFKYTNNNKQMLNTPGDGKLVNTIRSIYGKEI
                     TENIIDVEFKCNHFKMNGYIGNNNIYRSNKNLQHIYINKRFVKSKIIIDAITESYKSI
                     IPIGKHAVCFLNIEVDPSCIDVNIHPNKLEIKFEKEQEVYIELRDFLKVKLIHSNLIG
                     KYATYSDKKTQPRIAINSREKSTDYKLRNNDLLESTPKNSNITKGKDEVIEVVTLSSE
                     KPINEFQSVSEVLNASVEDDVKNINYLSEDSANDNIQEEFQVDGIKNEGNYYLGDSIK
                     DSEEEYLCSSKRKFSLYGYFVIGVVFNTYIILSKDDSMYLLDQHAAHERILYERYMEK
                     FYRQDINMQILLDPVVIEVSNIDMLQIENNLELFMKFGFELEIFGNNHIMVRCVPTIF
                     GVPETEKFILQIIDNIEEITSNYDLKGERFASMACRSAIKANDKIYDIEIKSLLEQLE
                     KCENPFTCPHGRPIMVEISKTEIEKMFKRIM"
     gene            complement(36386..39229)
                     /gene="mutS"
                     /locus_tag="PC494_001679"
     CDS             complement(36386..39229)
                     /gene="mutS"
                     /locus_tag="PC494_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HDF3912183.1"
                     /translation="MQIDMNKLTPMMKQYLEVKNRYKDCILFFRLGDFYEMFFEDALV
                     ASKALEIALTGKACGLEERAPMCGVPFHSANSYISKLVENGYKVAIGEQMEDPSTAKG
                     IVRREVIRVITPGTVLDGNLLENKKNNYLLSLYKDGTNIGLTYVDISTGETNATCLNE
                     DKVIEEIAKIHPTEIIINDLDFIEKLRDIATVSNIYINESFSDNYLDINILKEYFPDV
                     YLQKLKFDDKGLIKSSLSILLNYIYNTQKQITSNINNINIYNSSEYMVLDMFTRTNLE
                     LTQTIRGNKKKGSLLHVLDKTSTAMGGRLLRKYVEEPLINKSKIENRLDVIEEIKDDF
                     ILREDLNDILKNIYDIERICGKIAFERVTPKELIHLKNSIEKLPNLKDTINLSNAKIL
                     KEYVSEMDKLDDIYNLIDEAILEEPTITIKDGNIIKSDFSDELKELREISKNGAFLVK
                     EIENREREKTGVKSLKIGFNKVFGYYIEITKANFKQAKLDETYIRKQTLSNAERYITP
                     ELKEIEEKILHAEEKIKSLEYEIFVEIRDTIYKNIDRIQKVAKTIANIDVFVSLATVA
                     HINNYVKPAINENNKLDIRNGRHPVVENIVGEENFVPNDTYLNRGENIINIITGPNMS
                     GKSTYMRQTAIIALMAHIGSFVPAESADIPILDRIFTRVGASDDLSQGQSTFMVEMNE
                     VSLILKNATERSLVILDEIGRGTSTYDGISLAWSIVEYIQKNIRCKTLFATHYHELTD
                     LEEEFKEVKNYSIAVKEDGEGIIFLRKIIPQGADKSYGIYVAKLAKLPDEVIERAKYI
                     LKDLEKNHVYNSVAINGDKENNNIINSNLDEELVKVNQSNFKNKYESLKIEHELIVKD
                     YKHIKKDYDKLNSKFKALNDEVALMKQNDDKEKINQEDSVKEVALTQISFDSVNRDIL
                     SEEILNLDILNMTPLDAINSLYNLQRKAKEIKS"
     gene            complement(39390..40124)
                     /locus_tag="PC494_001680"
     CDS             complement(39390..40124)
                     /locus_tag="PC494_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF3912184.1"
                     /translation="MLTQMNFYHNKKVKVSIENVSKTYKDIEVLKDISIDVYEGEFVS
                     ILGPSGCGKSTIFNIITKLTDYDSGKVNINGKYSYMYQKDLLLPYKTIIDNVSLPLIL
                     KKEKKSKARSMVKPYFEVFGLSGYEDKYPSELSGGMRQRANFLRTFINSNDIMLLDEP
                     FGALDSLTKTSMQKWLLDVKKKVNSTILLITHDIDEAIMLSNRIYVISKKPSIVKKEF
                     VIDSRKLNEDNLENIIKLKKEIISLL"
     gene            complement(40093..41106)
                     /locus_tag="PC494_001681"
     CDS             complement(40093..41106)
                     /locus_tag="PC494_001681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDF3912185.1"
                     /translation="MNFKKLGILGLVSVFTLATITGCSSNNNKDKNNDKDTSSKKVTM
                     VLDWTPNTNHTGLFVALDKGYYKEEGLDVEIVQPPESGAETLVATGKADFGISYQEQV
                     TYAKTSEDPLPIKAVATVIQHNTSGFASPKEKNITTAKDFEGKTYGGWGSPSEEAVFK
                     AVMKKNGADFNKLKIVNTGQDDFFAAMKTVDFAWIFEGWDAVKADLIGYDLNFIPVKD
                     LDERLDYYTPLIISNETVLKNNPELAKKFLKATTKGYEYAIKNPEESAKILVKHAPEV
                     DEKLALKSQEYLASKYKDDAPRWGEMKDSVWNNYTSFLKEYKLIDKDMKASDAYTNEF
                     LPQ"
     gene            complement(41128..41898)
                     /locus_tag="PC494_001682"
     CDS             complement(41128..41898)
                     /locus_tag="PC494_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF3912186.1"
                     /translation="MKNLEIIDKVKDSIYPIATFLFILILWQSMVGVLEVPQYILPTP
                     VDIINVFFKDYQNLSIHAVVTIGEAILGFIVAIIISLVIGILMDFVSIIKKCLYPIML
                     VTQMIPTIIIAPLFMIWFGFGTMPKVLMVMLTCFFPILISFVDGIENIDKDYLNLFKT
                     MDSNKVNTFIHLKFPMAMDKFFSGLKISATYAVMAATVAEWLGGTKGLGVYMLRSKSA
                     YALDKVFASTILVVIFSLMFVGIVQAVKKVVIRHRLID"
     gene            complement(41873..42163)
                     /locus_tag="PC494_001683"
     CDS             complement(41873..42163)
                     /locus_tag="PC494_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MTH1187 family thiamine-binding protein"
                     /protein_id="HDF3912187.1"
                     /translation="MVIADIAVMPLRPYKGEEEMYKVVDACIAEIEKSGLKCEIGAMS
                     TTVEGDFDEVFELLKKVHKIPFNLGCERVITVARVDEKAGGLTIDEKLRNHR"
     regulatory      complement(42294..42393)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     regulatory      43013..43102
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            43155..43331
                     /locus_tag="PC494_001684"
     CDS             43155..43331
                     /locus_tag="PC494_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3912188.1"
                     /translation="MFMDKMDRCTHILTAYICSSRDYCNFIDTQLNDFILEYGENVVE
                     SCLHQVMVLVSRYN"
     gene            complement(43446..43802)
                     /locus_tag="PC494_001685"
     CDS             complement(43446..43802)
                     /locus_tag="PC494_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF3912189.1"
                     /translation="MDIDNNFEEFPNIEERQKDFNCSIGFTMTVIGSKWRAIILWHIL
                     KQEPIRYSQLKKEVVHISHKILSQELKYLERDGLIKRISYPTIPPKVEYLSTKRGKSL
                     ESILLELCNWGKQYMR"
     gene            44058..44971
                     /locus_tag="PC494_001686"
                     /pseudo
     CDS             44058..44971
                     /locus_tag="PC494_001686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007061260.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PhzF family isomerase"
BASE COUNT        15390 a         7017 c         5185 g        17481 t
ORIGIN      
        1 tatctgttat tttaatatta tagcacactt atagtattta acttatatcc actttacata
       61 tgtctaattt atataattaa aaatgcttat ctcaaataca ataattagtc cttatacaat
      121 taaaccatct gaaactataa tagtacgact actacttttg gctgcttctg gtgagtgagt
      181 taccataatt atagtttgtc cattgtctct gtttatttta ttcagtaaat ctattatttc
      241 tatccctgtt ttactatcta aatttccagt aggctcatca gcaaataaaa tctctggttt
      301 tccaattaaa gctcgagcta tagcaacacg ttgttgctga ccaccagata actctcgtgg
      361 tgtatgttta cgtctatcag ttaaaccaac tatatctaag atttcatcta attgattttt
      421 ataatctttt aaatttttac catctaataa caaaggaagc attatatttt cctccacatt
      481 taaatttggt attaagttat aaaattgaaa tacgaatcct atatttctac gacgtattat
      541 gctcattttc tcatcattaa aatgtgatat atcagctcca ttcatataca cttttccgct
      601 cgttggagta tctaaaccac ctaaaatata taaaagagta cttttgccag aaccagattg
      661 acccatgata gaaacaaatt cacctttcat tacttgtaaa gatacatctt ttaacactcg
      721 agttgttgta tttccaattt tatattcttt gataatattt tttgcttcta cagctaaact
      781 attatgtgta attttcatat taacctccat aattattcaa acttaatttc ttctatcagt
      841 ttcattttct tcccttttat aataggcact atcgaaccta ttaaagttac tataattccc
      901 aataacccaa caataataaa tgttttaaaa tctaaatctg gtttcattga aatttttggt
      961 cctgcaacta taaagatagt ttgaatctca agtatagata tcacaatacc aataacagct
     1021 ccaagtaaac ctgaagtaaa cccttcaatc aatgttactt ttatattttg tttatcactt
     1081 agtcctatag atttatacat agctatagaa cgtctttttt gaatataatt aatcagtaga
     1141 ttattaataa tacctactgt agcaagaaga aaaatgaaat aggtcatctt attcatagga
     1201 gacaaaaaac tacttatagt atttaaagaa tcattattaa attcttcaac tgtacgactc
     1261 caattatatg tatctccaaa taaatatctt atctgaatca taacagcatc tggattgact
     1321 gctgtatata ctaaaaaacc ataattagtt ttatcaaaat cattaactgc ataatgtgat
     1381 ggtataacag cttctacatc atttgcacgg gatttaaaac tacctactat tttataagaa
     1441 aaatcatact tatcattaga tagagttatt gtatctccta tagataagcc tacttttttt
     1501 agagtatctt cattcaaaat aacagaacgt ttatcattaa aagcttctat tacttgtttt
     1561 tttatctcaa aatttgtata attgattcca aacatagagt tatatagttt tatattatct
     1621 gtaccctcta gtcttgataa tgttacacca ttaccagaaa tctcattatt cataacataa
     1681 agaggtaata tttttttaat tccatccata tgtctaacat cttcaataaa ctcttcattc
     1741 atctttccat ctgcaaaacc ttgtaattct gcgtcacgaa acacatctgt tatataagtt
     1801 ttgacaaagt taccaacaac acttattgca ataactgcag aaatacttat aaatagtaaa
     1861 gtgatattct gtattatatt tttgttattt ttcatatttc tagcagctaa tttaccctca
     1921 ttccctaaaa tatttttata aacaaactca aaaactatag acatgatatc agtaataaga
     1981 ggaatcaaca caatagtagc tacaattaat cccagtaatg aaaatccacc agctagatac
     2041 aatgtatttt caggggatat tcttggaagt aaaatagata aaataaacat tatacttcct
     2101 ataaaaagta tagaacgatt tgaaacattc ttttcttcta ctgttcctag tacaatattt
     2161 tttatcggca aatggctagc ttttttaaca ggtatatatg cactaaatga agaaacgatt
     2221 attgctacta taacagatat aatcactcca atgggtgata ttactactgg aattgatatt
     2281 ccttgttcga gagaatttcc taacccatga agcattaaat ttaaaacaac tacaccaata
     2341 ggaatagcaa ttaatcctcc tatacttccg tataatatac tttcaagcat caatatacga
     2401 gttacagttt tttcattggc accaatactt ctaaatgttc caataaaagg aagacgttct
     2461 aatgtaataa ccttataact gctgtatatt ataaatatac taagggttaa tgcaaaaaaa
     2521 cttattaaaa agaaaggcat tgtcttttgt ctagcatctg aaattatctt agtttcattt
     2581 atagtatttg ataccatata tttttcagta gaaagttctt cggataattt atttactaga
     2641 ttttctgtaa tttcttcttc tgactctata agaactcttg tatatccact gcctttattt
     2701 ataatttttg atagagtctc tttgggtagc agtgcattta cacctcttgt gttcctcaaa
     2761 aatactgtat cataagatgc aatatcacta acttgaaaag tataggactt tccataaatc
     2821 tgtaaagtaa tagaatcacc tttttttatt ttatattttg atgtaaagcg atttggaaga
     2881 ataattttat caccagaaaa atcagtaata ctatcgccat tttctaatcg tggcttgttg
     2941 attttattta gttgacttaa gtctgctgat ataagactaa attcttcata gtatccccct
     3001 ttattataaa tagcagagct ttccaataca ccaacctttg attttatagt atttaaatca
     3061 ggtatgtctt ctaaattggt taatatatct ggatttttac tttggacaga tatagtcgct
     3121 gtaccataca taccttttgc catttttctt tgtgcacttt cataagataa tccaattgag
     3181 aatgaaacaa aaagtaaaac tgttgataaa actatggaca ataacataac tgctgttcta
     3241 atttttcgtt ctttaatatt tgtgaaaata tactttaata taattttcaa acttacacct
     3301 tcttccctta tctaagatat ttcaatctaa tatttttata ctttaatcta aattaaatct
     3361 ctaatagact cctccatatt tttatcatta tatttataat atttttaatc aaatcacccc
     3421 ttaaataaaa aagattgata aactactata taaatataat aatctatcaa ccttaatata
     3481 ttttttattt gaccttaatt aaccttaatt aaataggaaa ggtgatataa aatgagctac
     3541 ctaatccagg tatactttca acagatatat tccctccatg aacttcaata atttgcttcg
     3601 ttattgctag tcctaaacca gttccttcta ttttttgttt tgtattgctt cctctataat
     3661 aacgattaaa caaatttgat gcttcttctc ttgacatccc ttttccatta tcagatataa
     3721 tgatttcaat tctttcattt aatgttatat gtacacaaac tttagtattt ttatatccat
     3781 atgtaaaagc attgacaata agattactaa aagctcgttt taatagtgta caatcaaaat
     3841 caaagttaat attatctata ttactcttaa attcaactat ttttgattca tattctggat
     3901 aatttaaaat atcaatggat aattctttca aaaatcttac taaatcataa ttatttttat
     3961 ttaaagggat tattccattt tttaattgat aggttaattt taaatcgttt ataagtgtat
     4021 ttgtatattc tatgttcttt aacatgattg aagcatattt atatactttt tcaggtgaat
     4081 aattagtact actatctgta agaagctctg catacccttt tattggtgaa agtggagttt
     4141 ttaaatcatg agttatattt gaaatccact cttctctcat aatatcagtt ttattctgta
     4201 tctcatcact tttatgaatt tcttcattta aaatatttaa actattatat atatcagcaa
     4261 aaacaccttt aatattaact ggaagatagc ttcgttttga aatatcgcta acagcagatg
     4321 taatatttga tatgcacttt gttacccagt aaccataagc aattccagaa accaaaatta
     4381 ttaaaaatat aatccctatg attgaaaata caattgactt accacctata aatttacctc
     4441 catcaaaaaa catattcact ttagatatat ttaatggaaa atatataata taaatatagt
     4501 catttttatt atttttaatt gtattaaagt atacagttcc attacttgaa ttattttggt
     4561 tagctaatgc taataattca gaattagaat aataatcttt atgctctttt ggttctaaaa
     4621 acccataaac tctatttcca ctagaatcta aaatttgcaa ccacaattga ttttctcgaa
     4681 gtttttctaa tccagactgt tttacttgtg gcttattatc tataaatacg atttgttcat
     4741 taaagttttc tgtaaatttt ttcggccaat cactacgaat aaattcacca tttggtttct
     4801 gaatagtaat aagtgataag aaaataccta ttactgtcag gattaagcaa ataaaaatca
     4861 tgaaaaaaat aatgtatgaa tgaaatactg ttttataact aggtttatgc atttaatcaa
     4921 ctcttttctt aaacttttat tttagtttga ttgttgctta tataaaatag acaataatta
     4981 ttgatatgta aaaatttatt taaaaataca actatctaca taaattatat ttatataatt
     5041 atatgttatc aagctgtctg ttgtatttaa taaatcattt tgataacata taaaagtaag
     5101 ataaattttt ccattaaata ccttataatt atacacaaaa tctctatata cgttaaacag
     5161 tatagagaaa attttcatag aaccatcttt ataggggata ctttataaaa gaataaaaaa
     5221 attataatat ataaaaactt cataggagtg taacaacatc agtaaaaata tgaaaacact
     5281 atataaaaat tcaaaaatat taagaataat gaaatacttg aaattgctta tatcaagaaa
     5341 ttttatataa tataaactgg tcaaatatgt tataatatta aattgtgaca agttcatgga
     5401 ggtgtttata tgaaaaaaca aaagtcgcca attttacttg aaatgcttgg actatttttt
     5461 ggttgtatat caatgagtat tggtataaat atgtttttaa aaccacatac aattgctcct
     5521 ggaggactta gtggtctatc attagtacta aacaaggtta caggacttcc agtatcagct
     5581 atcatgttaa ttataggtgt cccattagta atacttgctt ttagaattat gggtacaaaa
     5641 aattcattaa aaactttatt tggaacagtt gtattttcag ctatagttca attaacagac
     5701 ccattatcaa aactaagatt tactaatgac ttattattgt cttctattgc aggaggaatc
     5761 ctagttggta taggtttagg aataatgttt aaatcagatg cttctactgg aggaacagac
     5821 ttaattgcac tcatacttag taagaaattc ccaggaataa aagctacaaa attcatgtca
     5881 tgcctagatg gaatggttgt tatatcttct ggtatagtaa atcgtagttt agaaactgct
     5941 ctttactctg gtatagcact ttgtgtatta ataaaaatag cagatatgat aatggaagga
     6001 tttgaccatt caaaagcatt ttttattatc tctgatgaac ctgaaagttt aagacaagct
     6061 ataactgaag aacttgatag aggtcttact attcttgatg gtaaaggtgg atacactaga
     6121 gaaaataaag aagttctatt agtcgtagtt tctaaaaaac aagaacttta tctaaagaga
     6181 ttagttaaaa gaactgaccc tactgcattt gttattgtta cagatgtaca tgaggttctt
     6241 ggagaaggat ttaaaaattt agagaactaa taaaaattaa tattttaagt atatatacta
     6301 ttttaattaa aatacgattt attcaaaaag agtgtctcat aaacttttta gttcatgaga
     6361 cactcttttt tgtataaaat caaatgcatt ttcagtattt taacaataaa aacaggatta
     6421 tctatatttt gaggcaacca ctttattgaa attttattta gaaaacaatc attactaaat
     6481 aaccagcata gatattaaat gattatatct attgtttttt caattcatat tgataacaag
     6541 gaacattttt tacagtattt ccagtatgaa tttttttgat atactttcct gtacatttaa
     6601 atcctaataa atctaatgat tttttagaat tttggttttc ttcataggtt attgcaatta
     6661 ttttatttaa gtttagttct ctaaatccat actgtattac tctttttgtt atctcagtag
     6721 caaaatcatg tccccaatag ctcggattta tacatatacc tatttctgct tctaatgctt
     6781 taggatttat attattaaac cccatattcc caataacttt attgtctctt ttatatacta
     6841 tagcaaagtg gccaattttc ccttttttat atggatttag aaaaaatgat tttataaact
     6901 ttcttgtatc ttctaaagat ttatgctcac taaatggtaa atgttttact actattttat
     6961 ttttataaca gtcaaaaaaa tcttcaacat catctaatga tgcaggtctt agtatacaac
     7021 ttctagtttc taaggttttc atttgaggat attcagaatc agacatttct aatccccctt
     7081 tatacattaa tctaaatata ctgttcatat ttaaaatacg atattaatta tataaatgtt
     7141 ctcaaattaa ccttattttt atttttaata aaaactaatt actatatgaa tctttcaagt
     7201 ttacgaattt atctctattt ttatattaaa ttacttgtga aatatgtatt ctaaattata
     7261 tattattaga tatcatgctt aaaaattctt tggttgctaa ggataaagat atatctttta
     7321 aatggcagta acctatattt ctcttaggta ttggctcttt tatatctaat ttaaacaatt
     7381 tctcattttc caaataatct atgctaaatt cttctataac acaagacact ccaagattta
     7441 tatacgcaaa ttctaaaagt aattcatgag aacccaattc tatatccggg tttagtttta
     7501 taccttttga taaaaaatat tcatttacat aaagtcttga atttgcttta ttttctagca
     7561 ttattaaagg caatgtgttt aattcttcca atgatatttt cctacctttg tattctatgt
     7621 aatcatttgc acatacaaat atatcatgta tttcaataca ctcaacaata tttagtgtat
     7681 catcttctat tggcatgttt ataattgcta tatctatatt cccatctttg agtaaagata
     7741 taagttctct actcgttcta tttattgtag atacatgtat atgtggatac ttcttatgaa
     7801 aaatttctaa atattttaac aagaaaaaac gtgcagctgt atctcctact cctattttca
     7861 gagaaccgta ttctaatttt ttaaatttat ttattctatc ttctcctgat gatattaact
     7921 ttaatgcagt agtgacatgt tcacttagaa ttttcccctc tggagttaat tttactccct
     7981 tattgtttct ataaaataat aaagtatcta attgttcttc taattgcttt attgactggc
     8041 ttacagctgg ctgtgacata aacaattcct tagcagcaag agaaaaactc ttattattta
     8101 caactgcatt aaaaacctta taaagttcaa gttttatatt catatataat tactccttat
     8161 gtcaaatatt agtattattt attttactta taattatatt tgaattataa tatacatggt
     8221 actaatatga caatattaat tctttaggag gattttagat aatggataga ttagttggaa
     8281 ctgtttcaag aggggttaga gcacctatta taagacaagg agatgactta gttaaaatag
     8341 ttgttgattc tgttttaaat gcgtcaaaaa gtgaaaactt tgaagttagg gacaaagatg
     8401 taattgccgt tacagaagct gttgtagcta gagcacaggg aaattatgct cacgttgaca
     8461 atattgcaaa agatgtaaaa gataaatttg gagatgatac tgttggagtt atattcccaa
     8521 ttttaagtag aaatcgtttt gctatatgtt taaaaggaat tgcaaaagga tgtagaaaag
     8581 tcgtattaat gttaagctac ccttctgatg aagttggaaa tcacttaata agtattgatg
     8641 aacttgatga taagggaata aatccttggt cagatgtttt aacagaagaa aaatacagag
     8701 aactatttgg atataacaag catacattta ctggtgtaga ttatgttgat tattataaga
     8761 atttaatcaa ggattgtggt gcagaggtag aaatagtatt tgcaaacaat ccaaaaacta
     8821 ttcttaacta tacaacaagt attttaactt gtgatataca tacaagacaa agaacaaaga
     8881 gaattttaag acaaaatgga gctaaaaaag tatattcact tgatgatata atgacagcaa
     8941 gtgtagatgg tagtggttac aatgaccagt atggactttt aggttcaaac aaagctacag
     9001 aagaaacagt aaaattattc cctataaatt gtgatgaagt tgtaaacaaa atccaaggta
     9061 atataaaaga aataacaggg aaagatgtag aagtaatggt ttatggagat ggagctttta
     9121 aagaccctgt aggtaaaata tgggaattag ctgacccagt agtatctcct gcttatacaa
     9181 aagggctaga gggaactcca aacgaagtaa aattaaaata cttagcagat aatgattttg
     9241 ctgacttatc tggtgatgag ttaaaagaag caatttcaaa atacatagtt gaaaaagata
     9301 ataaatctga tgatttaaca ggaaacatgg tttctcaagg tactactcca agaagattaa
     9361 cagaccttat aggttcttta gcagatttaa catctggaag tggagataag ggtactccta
     9421 ttatttacat acaaggatat ttcgataact atacaaaata gtatgtttta ataagattta
     9481 aattttttgg attatatata ttaacatgaa aatttattaa aacctcttaa tagatatgac
     9541 ttttcaagag ttatatctat taagaggttt atttaatgtt cacagataag atatatttaa
     9601 ataatttaaa caagattgtc agaaagttat ataatcttaa aaatttatat aactctaatt
     9661 cttatttatt tctgaaataa tatcactctt caaaatttgt cttactggaa taattacagc
     9721 aactatacta atagtgatat ttaaaataat catacctatg tatagaggtg tatttatttt
     9781 aagaattgga tttatatata agtatacacg ttttaccata aaataaatca taaattgtcc
     9841 aataacactt ccaattacca ttataatact tgcatagaat ccatataaaa aaccttctct
     9901 tatcatcata agtaaaaact tattatccgt aatacccata gctcttaaaa ttccaaactc
     9961 atgtcttctt gaaaaaatta agtagcttac tgtattgatt atatggaaca aacttattgc
    10021 aagaagtaca aatacaatac catatataaa taagagtttt tgatttaagt aggtattatt
    10081 tttttcaata gcaatggtat aatctgttac aatacatctt tttacatcac ttacaacact
    10141 ttttatgttc tcagacaatt cctcactgtt actatcttct gtctttttta tacttactga
    10201 attataattt tcgatatcaa agttattttt catttgccca ttcgtcataa ctatatccat
    10261 accataatca ccaatgaaat atatgttatt tgccatcaca cgttttacag tagcagcaac
    10321 tacaaattct tttgttgtat aatcattctt attttcttct ttaaatttaa caatttcatc
    10381 tgttggtttc attgtctttg gcactttaac ttttattgta tctcctggat ttatatcaac
    10441 tgcatcatac ataccagttc catccatagg tagtctaact ataaccttat tatttttaac
    10501 catatcatgg gtattaatct ccccatctat aatataagaa tttaatcctt ctaacatacc
    10561 attgttataa ccataaatat ttgtttttaa aagatagcca ccttcatttt gctttgtaca
    10621 aataccatca aaaaaagtct ttatcctgta atctttttca agaggtttaa agaaattttt
    10681 ccaaaatagt tgttcttctt taatttgcat agctccaaat aaatatctta ctggatagac
    10741 ttttgatatt ccctcaacat tgtttaatct tgaaatttta tcttttggta tacctacatc
    10801 aaaatctgtt gtttgcatag ttatttggta gtcagaattt aaaccatcat cagctttcat
    10861 tgtaagttca ttattatttt tagtaagctg tatagagtaa ctagaacata gaaatataat
    10921 tccaccaagt gataatgaaa acaaaattcc aataaacatt cccttttttt gagtcatgta
    10981 tttatgagat aatacttttg tcatgttaga gtgttttaca ctttctaata ttctcttttt
    11041 cttattagta atcttaaagt ttttcataga ttctatacta gagtatttat tcaactgatg
    11101 tacaacacgt acagcaatta aaattaacaa caataagata aataaaaagc ctaaataaat
    11161 agatttttca cttataaaaa atgctcctgg aacaatatca ctactcaaaa atatatgtgg
    11221 aaattgttca tatattgtag acgccacttc aatacctaag aagcaaccta taggaaatcc
    11281 aacaataaaa agtaaaaata actctaaaaa tagtagaaat aaaagttgtt tattattagc
    11341 gcctaatact tctaaaaccc catattgtga tattctctga agtattgaaa catggaaaat
    11401 actatatact gctgctgcac caaacactcc aacaagtaat ataattgcat ttgtatttag
    11461 ttctaaattt tttaagaact caaatatatt atatttttct atattttttg gtggttttac
    11521 tccaaattca actgaaagag gccagtttat ataagttttt tcttttgata tgttgaattt
    11581 tttcataaat ttataatttt gctttttaat atttttattt tcatcatatt ttacataaac
    11641 tatataagaa tccttttctt taggctgaaa ataatcgttt acaaatccct ccagagcagt
    11701 ttctgggttt gaaagacttg ataaaatacc acataactta tagattttac catctaaatt
    11761 gatttctgtt ccaatttctt tgtttacatt taaattgttt agagaatatg tgtcaagtac
    11821 tatctctcca tctttactag gaagagttcc ttttaataat tttctacctg tcatgtctaa
    11881 atatgaagaa tcagcattta aaaattctat aataaaaggt tcatctatct gatttttagg
    11941 ttttgtaatg ccaagtctat ctacagtgta ttcctttgat tttttatttt ctttaatttt
    12001 attaagttgt tccttatcta ctttatagaa ataatgataa tctccactat cttcccttat
    12061 cttttcaatt ctacttttgt ctgcactatg aactaaagaa ccaattcccg tcaataatgc
    12121 tactgatagt actatgctta aaactataga tatagattgt tttttataat gctttatata
    12181 ttgaattgaa aattttacta gagacatcat agtacttcac caccagtatt caccacaact
    12241 ccatcttcaa tatggataat tgagtcgcat acttgtgcta tattttcatt gtgtgttacc
    12301 ataagtatcg tttgatggaa ttttgcacta ctttctttta ataaacatac cacttccatt
    12361 gtagttttac tatcgagatt tcctgttggt tcatctgcta atataagcgc aggtttattt
    12421 gccaaagctc tagcaattgc taccctctgt tgttgaccac cagatagttc gcttggaaat
    12481 tttaaacgct tatcccaaat tcccaatgtc ttcatcagca tttcaatata ttcatggtct
    12541 atatggtttc ctttatctaa tgtaacagga agagctatat tatcataagt gtttaatacg
    12601 ggcattaaac tgtagttttg aaatataaat cctatatttc ttcttctaaa tactgtcaaa
    12661 tctttttttc ctattttaga tatgttcttt cctttaatta ttacatcacc tgaagttgga
    12721 ttatctaatc cacctataat atttaacaat gtgctttttc cagaaccaga agttccaact
    12781 atagcagtaa atgtatctcg ttcaatttct atacttactc catttaaggc ttttacttta
    12841 gtctcacctt ttccatagtg ttttactaaa ttattcgtca ctaatatact catttaattt
    12901 ctcctttcaa tacagatata tgttctataa aatattgtaa gtgacgataa ttacactcat
    12961 cctacaaaat tagtttaaac tcttacaatt ctgtaagaag atactaaaac aacatccact
    13021 tcctagttta gattctacta taatgtttcc attttctttt tctaaaatta atcttgtaag
    13081 atatagacca atccctgtgc cattttggtt ttccacattt ttacttctgt aaaatctttt
    13141 aaaaatatca tttagttctc tactatcaat acctattccc tcatctttaa tagtaatctt
    13201 cgtatatagt tccattttta ttacagaaat agtaatcgtg ctatctgatg gtgagtattt
    13261 tattgcattt tctaaaacat ttacaattgc ttctatggtc cactttttat tatgaactaa
    13321 ctttatgtct gaaaatggtt cgagatttat ccttatattt ttagcttctg ctttattaaa
    13381 gatagtactg atactttgaa taagagtatc tttaattagt agttcttcta cttcaaattc
    13441 tataactcca tcctctaatt tagtcatttt aaataaggat tgtaacagcc agtcaatctt
    13501 aaaagtttca tttttcatct tttgtaaaaa ctccttcttc tgtaatgtgg aaatatttat
    13561 attctccaga agttcacaat aaatggttat atttgaaagt ggagttttta attgatgtga
    13621 catatttgat attaaacctt taatcgcttc tttttctgac tttgactgtt ctacctctat
    13681 ttctatcata tccttaattt tttttacttg gtgagaaatt tttgacgctc ttgtatcctt
    13741 tgtatctgga taagtaactt ctttaccttc caatatttga tttaacatca aatttaattc
    13801 atcatatctt tttcgattta ttttagtaga tactataaat ataacaactg tacatattat
    13861 aaaggctaat ataaacatat tattctacct cattccataa ataacccatt ccataagctg
    13921 tttttatata ttttggatta gatgggtcat cctctacttt tactctaagt cttcttatat
    13981 ttacagatac aatattatca tcaacataat tttcttcgct gtcccaaata tggtgtaaaa
    14041 tttgttcctt taataatatt tgacctttat tttcaattag ataacttaga agcttatatt
    14101 ctacagagct aagttccaaa cattctttat ttttatatac ttttagtaac ttttggtcca
    14161 attttattcc attggaatat attactttat tattcgattt ttttcttatt gctactttga
    14221 ctcttgcctt taatacagat aaagaaaatg gttttgtaat ataatcatca agccctattt
    14281 ctaatccttt tacttcatca atttctgagt ctcttgcagt aagcattata attggtatat
    14341 ctgacttttc ccttattatt tgacatacat caaatccata tccatctgga agattgcagt
    14401 ctaagattat aaaatctata tttttactat taaatatatt taatccttct tgttttgtat
    14461 aagccttaaa tacattaaat ccatcattct caaatgcata aaaaagacct tcatttaagt
    14521 ttatatcatc ttcaataatt aataagttca attttactct cctttagatt ttttagataa
    14581 ataattattt tcttgcatta tcatactaaa aatattttaa ttttatttat ttcactaaaa
    14641 agattgtatt taaatttgtt ttcaaaataa aaacatcata atcaagcata tagttatata
    14701 tttcccaatt taattacgct taaattgaaa atataacttt attcttatat aattaaatta
    14761 tacaacaata aagttatatt ttttaaatat atttttacta gggggaatag aattgaaaag
    14821 ggttgatgag agaaatacta tgtttgcaag agcaaattac aaaaaagata gtactgctta
    14881 taatgattat tataagaaaa atcctgacaa aaaagaaatt gatgatagta taagaaatag
    14941 accaaattta tgtagtgaag gaacaatgac ttacaatgag ttaaactctc caatggcaag
    15001 tagtgcattc gattttttat ctgatatcaa atctttatgc gaaggaaaag tttctgatac
    15061 taaagtagat gtagatgcaa agtcaatgac aaaaaaaatt aagggtcttg caaagcagta
    15121 tggagcttct gtagttggta taactaaatt aaaagactat catatttata caaatagggg
    15181 tagacatgaa gaaaattacg gtgaagaaat taatctaact cataagtatg caattgtatt
    15241 tggatgtgag atggataaag aaatgataaa tagagctcca atgatatgtg aagttataga
    15301 aacatcaaag tgctatgtgg atgcatctat cgtcggcatg attttaagtt actatataag
    15361 aaatttagga tatgatgcta gaaatcatat ggatgctaat tatttggtaa tgcctgtttt
    15421 tatagctcgt gatgctggtt taggagatat aggaagaaat gctatactta cgaataaaga
    15481 ttatggctct agacttagat taggtgttgt tactacagat attcctcttt tagaagatga
    15541 atatgttgat tttggactag aagatttttg taaggtctgt aaaaaatgct cttttaactg
    15601 cccttctcat tcgctttcta atgatattaa aattggtgat gatggaaaat ataattgggt
    15661 aattgaacat gagacatgct atattaaatg gagatattta ggtacagatt gtggtatgtg
    15721 tatatctgct tgcccattta gccaaaatct cgaaactata aagaatacta cttcatttaa
    15781 gggtaataat gagcttattc aaaaagcttt agatgagtat acttcaaaat ttggtaaaag
    15841 aatatttata cctggaaatc catcttggtt gaaataattt tatttaataa agaatctgta
    15901 ctagaattta tcataggaca ggttctttat taaatatata aatttttaaa tactttttct
    15961 cgtttataac aattcagcaa tgtttttagt ctataattga cattataaaa tattaaacta
    16021 aaaggagtaa ctgtatggaa aaaatattag tagtagaaga tgattctata ttaaataaaa
    16081 ctctatcata taacctaatt gaagatggat atataattac ttcaaaattt acagctaaat
    16141 ctgcactgaa gtctattttt gaatgtgaat ttgatttaat aattttggat attaatttac
    16201 cagataaaag tgggtttgaa ttatgtaatg aaataaaggg aaattacaat ataccaataa
    16261 tttttttaac tgctaatgat atggaatgtg atatgattaa aggctatgaa cttggagctt
    16321 tggattatat aacaaaacca tttaatatca atatatttaa acagaaagtt aaagcttttt
    16381 taaatcatct tacaataaaa acaaaacaag attactatag ggatggatat cttgaaatta
    16441 acttttctga gttatctgcc aatataaatg gaaatcaaat tatatttaca ccattagaat
    16501 atcgtacttt aaaactgctt actgaaaatc ctaaaagtat tttaacaagg aaagtacttt
    16561 tagaaaaact ctgggatata gatgctaact ttgtagatga acatacttta acatctgtta
    16621 taagtaggat tagaagcaaa attgaaaaag acaatcttaa gtatatcaaa acggtatatg
    16681 gtatgggata tatgtggtta ggtgaaagaa atgaatttta aaaaattttc ttttagttct
    16741 atttatttaa taattgctgt tggtataatt tttacagcta ttttatttag tatctcaatt
    16801 tatctaataa ctgctgattt aaaactaatt gctctattat taatatatac aatagtgctt
    16861 tgtggattta tagcattaat aatattttta cttcataaaa aaatagttat attttgttct
    16921 aaaatatgtc acactttaga tagtatgatg aatagtgaag acaatattga aattgaatta
    16981 gaagaagaaa ctattttatc acgtatcaat cacagattaa ttagaatgta tgaagttatt
    17041 caagaaaatc gcaatagtat tgctatagag aaagctgatt tacaagaact agtttctgat
    17101 atatctcatc aaattaaaac tcctattgca aatttaaaaa tgattaatac tactctacta
    17161 aatcaaacat ttaaaacaga aattcaaaag gattttttaa tggatatgga aaaccaatta
    17221 gataaattag attttttaat gcaatctatg gtaaaaacct ccagactaga gacaggtata
    17281 atcacactat ctaaaaagaa aaattcaatt tatgaaacaa ttgctacagc acttagtgga
    17341 attttgtttg atgctgaaaa aaagaatatt gaagttacag ttgattgtga cccaaattta
    17401 tatataattc atgacaagaa atggacttct gaagctattt ttaatatatt agataatgct
    17461 gtaaaataca caaattctaa tggtaaaata cgtgtagcta cagaatgttg ggttatgtat
    17521 acaaaaatag atattattga taatggaaaa ggaatatcag aaagtcatca agcagaaatc
    17581 tttaaaagat tttatcgtga agaagatgtc catgacatag aaggtattgg aataggtctc
    17641 tatctttcaa gaaaaattat atctcttcaa ggtggctata ttaaagttac atcagatatt
    17701 ggaaaagggt cgactttttc tattttctta cctaataaat aaatttttaa atatttcatt
    17761 tgtaatgatt ctgcaacatt ttggttttat actgtattta caagatgtta aggaggtatt
    17821 attatgagta ttttacaagt aattaattta aagaaatatt atggacaaag ttcaaacatt
    17881 acaaaagctc ttgatggtgt aactctatct attgaaaaag gcgaatttat ttctattgta
    17941 ggtacatctg gtagtggcaa atccacatta ttaaatatga tgggaggatt agataatcct
    18001 acatctggaa aggttattat aaagggtaag gaattatcta ctatgactga tgaacagctt
    18061 acaatcttta gacgcagaaa tataggtttt atatttcaaa attataatct tgttccttta
    18121 cttaatgtat atgaaaatat tatcttacca ataggattgg atggagagac catagataag
    18181 gattttataa atgaaattat aaatatgctt tctcttgaag aaaaattata tgatatgcca
    18241 agtaatcttt ctggtggtca acagcaacgt gttgctatag ctagagcact tgtaacaaaa
    18301 ccagctatta tactagctga tgaaccaaca ggtaaccttg atagtagaac tagttcagat
    18361 gtactgagtt tacttaaagt gacaagtaaa aaattcaacc aaacaattgt aatgattaca
    18421 cacaataatg aaattgcaca actaactgat agaattattc gtattgaaga tggaaaaatt
    18481 gttaactagg aggtgtagta tatgtttaga aataataatc gcacatttat aagaaaaata
    18541 gctttaaatg atttaaaaat taataaactt aaaacatatc tttcaggtat cattataatg
    18601 atttctacat gtttattatt aacagtgacc ttagtttcat ataatgcctc tgtagattta
    18661 gttaatgcat ctccatatca tgctatatat aaatctgtag atgaaaaagc aaaaaatata
    18721 ctatataaaa ataaaaactt tagtggcgta ggaacttaca aattaattgg aagtaataaa
    18781 aagacagatt gtattatgtc gattgtttat gcagatgata caacaattaa acttatgaat
    18841 tttcaaccat tgaaaggcaa actacctaca aataaaaatg aaattgctat ttcagaaaaa
    18901 tatttacagg aatttggttt agataaagat attggagata gcattaaatt aaattattat
    18961 gatgatatta cgaataaaga agttcaatgt gattttatta ttgttggatt tctagaaaat
    19021 tattatcaag ataatgccaa gcaatactat acagtcgttt caaatgatta ttttaagaat
    19081 atagcttcta cacctttaca aaataaaagt aatacttttg acgagtcaag acctgatact
    19141 gtagatgtat tagttaaact atcagaagaa aatacagaga aagattcagc ttcaattaag
    19201 acacagttaa agaaaattgg tttatcttta ggtattaaga aatataatat atacttaaat
    19261 gataactata ttgaatcaaa tttaattgat ggtgagcaga ttattacagt tttagtagtt
    19321 ggaatagttg ttcttttttc tagtgttttt gttatatata gtatttttta tatttcagtt
    19381 gttaatttag ttcagatgta tgctaagttg aaatcgttag gtatgacttc tttccagtta
    19441 aaaaagatta tttttctaca aggaaatatt ttgtcaatta tttttattcc attaggggtt
    19501 atagcttctt gtataattgc ttacataatt caaccattag catggcaaat gatagctgat
    19561 ttatttataa ttttaatttt atcactggta atgtttttaa ctgttagaat ttctttattt
    19621 aaaccagcta gaattatttc taaaatatct gctattgaag ccatgcaata tacagaaact
    19681 aaatttagaa aaaaagtaaa aaattttagt tatataaata taaaaaatct agcattaaag
    19741 aatatcgagt caaatagaaa gaaaaatttg attgcattaa tatcgctaag tattagtgga
    19801 gttttattta tttcaatcgc taatcttgct aattcaatag atttcaaaaa acaactatct
    19861 caacaatttg tctataacga agattatata attagcatta agagtgataa cttatatgag
    19921 catattacag aaatccaaca aaataatcca ctaacagatt ctcttaagaa tgaaattaaa
    19981 tctattcatg gagtaaaaaa attaattgaa tccaaattaa ttaaaagtaa tattatagaa
    20041 ccttacatca aagatagaga cgaaaaacaa tttattactc taattaaagg tattacgcct
    20101 gaactttcaa aatcacttga agaatatatt gtcagtggaa aaatagacta tacacattta
    20161 gattcagata gtttaattat aaataaatat agaacaaaat attatggatt aaatttaaaa
    20221 gttggagata cagttacatt taatatcttt agtggaaatg atattattaa aaagaaaatg
    20281 aaaattatag gaatcattga caattccaat acagaaggta tgttttttgc ttcagacaaa
    20341 actttagaat ctctaacacc atataataca aatttagatt tttctatttt aatagataaa
    20401 aagtattcta aagaagttga agaaaagttg ttaagtataa ttcagaaaaa ttcaaattta
    20461 atgctttatt catatgaaga tgattataga atgattacta gagcatttca atatataatt
    20521 atagcttcat acatttttgt tggtttaatt tcttgctttg gtatactaaa tatgaccaat
    20581 accctaataa acagcgtttt aattagaaaa aaagagtttg ccttacttca agccgttgga
    20641 atgacaagaa agcaactgcg aaatatgctt tatagagaag gtctaaacat aagtatcaaa
    20701 gctatatgta cttcaagtat actaggttat tttggttcaa atctactttg cacttttata
    20761 aaagatgtaa ttagattaga ctttattaat tttaaatttt ctatatttac tattttaatt
    20821 ttttcattcg tattaattgg tatacaagtt ttagtgactg aattacttgt aagaaatata
    20881 gaaaaaaaat cacttacaga acgcttacgt tctcagtaag aatgtatata aaaaatagcc
    20941 attttttata caagttttaa cataattttt taaaagctaa aaggatagaa aattttgact
    21001 ttacataatt ttctatccct atacttgttt ttattttata cagatacact tccttatatc
    21061 tccgagcaac atcaccagag acataaacaa gcatattcct tattttctaa atatgtcaat
    21121 tgcatgactt gtaaccccta ctaaatcttc acgttcacaa gtagcaaggt gatattttaa
    21181 gtataatgca aatgcatcat catccataga gtctactgct tcacgcatat acaaagccaa
    21241 accatctgat gcgacataat gcagtctagt tacattaaat gcagacatca aatcatcaat
    21301 gttttcttta cgtacaagct caaacaaatc ctttggttca gacttagcag caaatgtctg
    21361 tggatcaatc aaaccttttt caatatattc agatacatta atatttcctc tatggaaccc
    21421 ctcgtcaatg agacagccat cagatataac atatgcagca aaaaccacac caccaggttt
    21481 tgttacacga attgcctcat gtaaagcttg ttgtttatct tctttgttat aaagatgata
    21541 tagtggtcct aacagtaacg taatatcata tttattatct gggaaaacag ataaatccat
    21601 agcattaccc tgagtaatgc ttatattttc atttgattga gtatttttat ggaaaacctc
    21661 tatattatgt tcgactaatt ccactgcgtc aacatcatat ccctgacgtg ccagtgtgtg
    21721 agaataacga ccagttgcag cgccaatttc aagcacacaa tcacctgatt ttatgtactt
    21781 atcaatgtaa tgcatagtag tgagaaattc caccattcca tgttttaatg caagtcgact
    21841 atcttcatca taagtattat aaaagtcaat taagtattgt tttgtttcca taatttcacc
    21901 tcttctatat tagttaataa acatcaaata gacaaattcc aatctggttt ttcttgtctt
    21961 ataaaagctg ttaatatatt tttcaacatt ttttcagcac tatatctatc taatgttagt
    22021 ttttttgttg ctgttaagac agctatgcca tgagtataaa gaaataaatc taaaaatatt
    22081 acttttgcac attccaactc tattccaatg ctttccgaaa aaagtcttgc ctttttttca
    22141 ttgtcaattt ctttataaaa atcattcgcc tctttcatca tcaaatctaa atcatttata
    22201 aataacaact taaataaata cgtttcttct tgagcaaatt caatgtatga aagcggaagc
    22261 agtaaataag ggcttacact tttagaatta cgataattaa caacatactg attataatat
    22321 tcatatgcaa aagcaagaaa ttcatttttt aattcattca tgttttcgta acaagtaaaa
    22381 attggtcgag tggaacactg taatttactt gcaatactcc tcgcatttac agcttcaaat
    22441 cccacttctc ttgtaatatc caagactgta ttcaaaatca tttcttttgt tatctttact
    22501 ttaggtggca tatatgttca cctctccatt aaatttttat aaaacacata tgttatataa
    22561 ctatagtaac atatcaagaa attatgtcaa gaaaaagctt tgcatttttt tgcaattcct
    22621 aaaacttata aataaaacat gagttgctgt tatctattaa tagataacag caactcagat
    22681 tttcctttaa atactcttct ttttgtctaa tatttcatat acacaatctt ctattgaatt
    22741 aatatctttt tcttttcttt ttttagaatc aattaaaatg aaatacagta taaaacctac
    22801 agcaagtccc catgttccgc ctttagcagc aattacacct cccataagtc caatcaatcc
    22861 cttctcaaca cctgtattac atagctccat tgatagcttt gtacataaat atccttgaac
    22921 taaaagtgtt actgacaatg ctaatggtat aagaggtgta gcaatctgcg caattggata
    22981 aaagcagata aaaattgctg aaacccatac taatgtaccc ataccactaa aaacagactg
    23041 catggcttcc tttccaatct tgtacctttg agcaacactt cctgtaagtg tcgcagctaa
    23101 tggaccacac attggtatat atggagaaaa gattgccata aaaatatttc ttatcccact
    23161 tataacatta gacctatttg aattgaaatc tatatattca tcttttctat tttcactttc
    23221 agaaagtact aaattttcac ctgttataaa atcaccaaat gcaattatgt atatcataaa
    23281 agccattggt atcccttgta taaataacat tacacttgga aaacctattc caaaaggaga
    23341 tactgtattt atcagatttt taaaatctac tatgtaaact aaattgtcaa aactaaatct
    23401 aggaatttct atttctctac taaatatacc tactattaaa ctcactaaaa tagctgatac
    23461 tacaccatat tctcctaaat gaaataaaaa tttattctta acttttagag tatcaaatct
    23521 ttcagaaaac attacaaaac aagcaaccaa aattcctact gttatagata taggataaga
    23581 atcaaatctc cctttaggat taaactctga tattatagtc gatataccga cacccattag
    23641 tattccacct ttaatagaat ttggtatctt actaactaac tttccagcta caccagttat
    23701 acccattaaa ataaatatta ttcctaaatc tatttgtaaa gctgttaatg cttgtattct
    23761 ttcaatgccc atgctgaact ttaacaaata tgcagttgta agagttatag aagctgtaat
    23821 ccagccaggt acaactgggt ctcccataaa aacatgcaaa cagtataata ttgagttaat
    23881 gatagccata ctccatgcca cttcataggg taatcccaat atttgtgtac taaggccaat
    23941 tgtgcctaaa cttgtcatac ttgatattat accttgaata gcttctggtt tctcaaatct
    24001 gtaatgtata aatggaattc ttatcttaaa cattccaaat tttatatgag gttgttccct
    24061 tctagcgagt ctttccataa cttcactcca cctttcaata actcttgtaa gtttacaact
    24121 ttataattgt ttataaatta tcaatgtcat taaaattagt atataacatg caaattatat
    24181 aaacaataaa ttaaatctat aaaattgata gattttgtgc atatatagaa agaccacttc
    24241 atttttagtt acttaaatca cttaatatta gttatttaaa tcacttgata aaggtttttt
    24301 ataaaattca atagttctat tccatgattc aaactgtcct tttgaatttc cttctacagt
    24361 tccacctgaa gaaaaaatcc ctccactcat actcatacat aaagtctcct ttagaggcat
    24421 aatatatgga attggtaacg gatgacccat attattgtat gttaataatt ctacgttata
    24481 tggataatta ttttcttcaa agatttctaa tgcctctaaa caagcttcat aactattcca
    24541 tatgttatct tcttttccag caatcataag tatatctgct ttggaatttt ctatttttat
    24601 tctagcctct tttctattct ctgctctttt aagacttttc ttataagtac tattaaatcc
    24661 aaatggaata tcttttgata tatttttttt ctgttcttca aagaatatat cattgtctac
    24721 tttgatatat ggaaatggct ctcctttata tgaccatgat gaagtatcat ttccactcat
    24781 caatccatta agagcttgga aacaataaat gtgaggttgt gatactacaa cctttttaat
    24841 ttgttcatat cttgaagcaa gtaaaaaggc caattctcca ccctttgatg tcccatgtac
    24901 aaatatttct ttagtactgg taatttcatt ttcactaatc cactcaaata ctttttcaaa
    24961 atattctaat ggaacctctt ctaatttatc tggtaaccct tctaaagcaa agtatgcaac
    25021 tgttagtaca ttgaatcctc tagatgcaag tggagctgct aaaaggtcta gagcgtctaa
    25081 atttccatca gaaccaccta gcattaaaat tgttttatta ttagaatttt gtttataaaa
    25141 taattttcct ataaactcat cagatatgta ttttgtggta atatcttctg atttaaatat
    25201 tctctttaat tcaacttctt ttctttcaat agaagtttca aatatcatat tcataattat
    25261 tggtttatca atagatatat tttctgcaaa atttttacct tcagttttag atttttccag
    25321 cgaataaatt aaccccatac aattatcagc cttataagta ccttctatag gttcaactaa
    25381 atctaaatct acttctcctt tttcatttga acaaaacact ccataagatg aaaattcttc
    25441 tcccttgcac catggaaatt ccattttcac acttatttta agtttagtat ttggaattaa
    25501 gtccgaaacc ataatcttaa gtctttcatc cacaaatgat tctacattgt atacatttac
    25561 tttcataatc tatttctcct tataataatt atttatgttt tatataaaac agctttatct
    25621 aattcaacat aaataaattt ttaaattaag acaccatatt gactatttca ttttatcaac
    25681 atattccatc tttgtcaata tattgtcttt tttagtaatt taaaattatg tagtctatat
    25741 gaaatccagt tgatttttgg ctaattaaag ataggaatgc tattaggttt aaaatatatc
    25801 tattcaaaat aaaaaaccac tcattttaag aatggttttt aatataaact atttgttatt
    25861 aataaggata tttttttatt taaatttata taatcgaaca tctaatattt aatgtttaat
    25921 aaaattatgc atttgcaaaa gtatatatgg cattaactct tgctacatat aaattctcat
    25981 cactacatcc aatatatcta gcatattttt caatcttttc ttttgcattt tcaacatcat
    26041 tttcatcgct ctccattaac tcatttatat aaatatccat taatgacgct ttatattctc
    26101 ttatatcata gcctaaaaat tcagtcaatc tctcaatttc cttactaaaa tctccatctt
    26161 cttttaccaa aaattcgtat acatcttccc tatatggatt taaagttatt atttgtttta
    26221 ctactttgca ttcgtcagcc ttcccaataa aaccatcttt ataattatta aataaggcat
    26281 tagatttttt tatagattct tcatcaatat aagaatgtac cgcagttata cgattttcta
    26341 taagggcatc tacaacagca taatgaattt taaaacaatc attgtataaa taattgctca
    26401 ttttctttat tgtcgattct atttctaaga agctcgcgtg gccatttttt ttatttttat
    26461 ttggtataat aaaagtttta ttcaaattat taaaaagtct cttaaaatct aaatattttt
    26521 cacaataaac acttttaaag gtatcgatat ctatagttat aattccaaaa cttactatag
    26581 tctcaattcc tttcttaaaa gactcttcta tatatttttc tcctaaactt aaacctctat
    26641 cagatatttg ctttagattt tgaaaactat ttaaacaatc tctttcaaag tttttagata
    26701 tttctaaagc atataattta aagattttcc ttatcttatt ataattattt tttgtatcat
    26761 caaatctgat aatagctcca tttacatcaa aagtaatcat tgagttttaa cctccccatt
    26821 agtttcatca ataaaataaa tttaatataa actttataat cataatatta aacttattta
    26881 tactataatt attaatttga tgataaaagc tattttcctt ctaaataaaa aatttgtcta
    26941 aagtttctaa aaaatttaga caaatcttag gttattactc tttaaattat ttttaaatta
    27001 ttccaaatac gccaaataat attggtataa atatagctgg taacaaattg gctactttta
    27061 tattcgttaa tttaagtaca tttagaccaa gtcctataat taataaactt ccagctgctg
    27121 tcatttctgt gactacagga tcacttaaaa atccatttaa aaatgatgct cccacacata
    27181 taataccttc atacaaaaat acagatattg cagaaaacat tacacctata cctaaagaag
    27241 cagtaaatat aattgaagct attccatcta taacagattt tacaaataaa gtatcatgac
    27301 ttcctgtaag accactttct aatgaaccaa ctactgccat ggctcctata cagaataata
    27361 aactagatga tataaaaccc tctgctatag aatctttttt atttccttta gaaaatttac
    27421 tttgtaaaaa agcacccaac ttatttaccc atttgtcaat atctattaat tctcctatca
    27481 gagcacctac agctacggat attattgtca ctaatgtgtt ttttccttct agtgctcctg
    27541 atataccaat gtacaataca cataaagcaa ttccattcat tatagtatcg cttactcttt
    27601 gaggtaatcc tccttttatt ataagaccta ctatacatcc acctgcaatt gctagactat
    27661 ttgctattac tccaaacatt ttttctcccc tcgattagct aattgaaatt tatcctatta
    27721 ttaaaaccta aacatctata ctttgtattg gatattttaa atattccaaa aattcttcaa
    27781 aaccttttct agatatattt acagttttag tatttatgtt aggatgaaaa tttaagtaat
    27841 cttctttaat tacatcttta tctatgtaaa gctcaacttt tctttctgta tcatttatta
    27901 atgaaaaagg atttacactt ccaggaagaa gtttaagtac attgtatagt ctttcaggtg
    27961 aagcaaacga taatctagaa cttcctatct tatctttaag tgagtttaaa tcaacttgtt
    28021 tttctccttt aactacaata agataatact tatttccttt ggcatttctt aaaaataaat
    28081 ttttacattg acaccccttt gttattccat ctaaaatgac taattgctct gctgtatata
    28141 cagcttcatg ctctactaca tcatattcaa catttaattt atccaaaata tcatatattt
    28201 tagtttcatt catgctagat tcattttcat cttgttcttt tttattattt aaatcactca
    28261 tacttttctc cttaaacact tcatcataat atcattgtga ggtattattc tactatagct
    28321 attgctctta ctggagctcc atcagcatca ttatacttaa atggtgctgc tataaataga
    28381 aatttttctg gaacattttc taaatttgta agattttcta tgattatttt tcctttttca
    28441 aataaaatat gatgcacttc aaatactgat gtgtcatatc tatccactga tagcatatct
    28501 attcctatgc cttttatatt agtattagct atatagtttg cagcttcttt tgttaatgta
    28561 ggataaccta catagtactg ctttttatcc caaaattttg accaacctga tttaaatatt
    28621 ataaaatcac tattttttat ttcatcttca tattttttta gatattctaa ttctatattc
    28681 tcatttccct tttcaagttc caatacataa gctttcccaa caaaattttc tatatccaac
    28741 ttatctaggg tctcaccttt agtatacata tgtcttggtg aatccatatg agttccattg
    28801 tgagaaaata cactaattaa tgtttcttga taaccatttt cttcaataat agctactttc
    28861 ttgatatctg gtctattagg ctctgcatat acaggcatgt cattatgtgt cacatgagtt
    28921 aaatcaaaaa ccttcatctt tatatacccc ctatgttttt attttctatt atatacctaa
    28981 attcatttta tttctatcag attttattcc attatatacc atactactat atatttttta
    29041 taaacctcaa gggatttacc gaaaaatctt ggaaagaatt atcagtaaat ataacatctt
    29101 cacccaaaaa acgtttatac cttccttctt ctttctttaa agtaattctc tgtttttgtg
    29161 aatgattatt aaaaaccatt atcttaagag gaggtttttt tctattagtc tgcactcttt
    29221 ttaacatgta ttttatgtgc atatcagctt caggaaatga atatccacaa aatattaaaa
    29281 ggtcagtatc tcttaaagtt ttttctgttt cattccaaac attacttaaa aatatgtttg
    29341 acatattctt aaaatatgtt ggtggcacta taataggttc tgttaactca ccacactcta
    29401 aacattttgt ctctgaacta ttttcaataa gcttcatgac accaccttca tgtggtgtaa
    29461 gagttacact attacaaatg gggcaataaa gccaattcaa tgacccatgt atcttatata
    29521 atttgattaa tggttctttt ggttttctcc aatttaactc ctctttaaaa tttgtaaact
    29581 ccacaccata atcaagcata attggcaaat cattcttatc tcttaatcca gtaactgtat
    29641 tgtctatatg tatatcataa tttgcactaa taaaagtagt atcaagaagc aaatcatttt
    29701 ccaaaagatt ttcaactaaa agtttatgat atttattatc tgttctaggt gtattatgaa
    29761 ttgcttcagc cattagcagt attaaatatt gtcttaaaaa acgtatacta tcacttctgt
    29821 tatttagatt ttctagtcca aaatttctaa atgcttcttt tctttgttct gctaagtcta
    29881 aaagacctaa aacttcttca aaggtaggaa aatttgcatt atctatatta tcttttacta
    29941 tatcaatatt gaacatctgt ttaaagaaaa tatacaattc tctattcatt ttggtattat
    30001 aatttgtggg atttagtttt ttaaaatatt cgctaaaaag ttcattttga ataggtagat
    30061 tctctgctgc tgaagctcct gctcctaaaa atattgctat tttcatatag ttcctcctaa
    30121 tataaatatt actcctattt ttatatccat taaatatcca tatcatttat tttatgatac
    30181 aacaataaag ctgtctttta ctagaaaaaa tcctattaca agacagcctt atattatatt
    30241 aaatctttaa taattcgtaa atagaaagag catatatttg agtagctttt ataatatcct
    30301 ctactattaa gtattcatta gcttggtgtt ctgtttctgg ttttcctgga aaaatagctc
    30361 caaatgcaac acaattatct aaagctcttg cgtatgttgc tcctccagat gaaagtggtg
    30421 ttccatcaag accagtttct tcttcatata cttttctaag tgtcttaaca agaagagtat
    30481 cttctggaac atagattgaa tccaagaaat catattcttc ataatttaaa ttgtatttat
    30541 ctgtcatttt ctttaactct tttacaaaat catccttttt gtatgttact ggaatcctta
    30601 catctattcc tgcaaattct ttttcgttat caatagttac tctacctata tttactgtta
    30661 gtttacctga tacatcatcc ttgcaattag gaattatatt gtttccatta gcatcttcac
    30721 caataacttc tgctaaaaac ttaattatat tagaatctat acctatatta ttaagagcta
    30781 tacaaagtct agccactgca tttataccag tatcacttgc tgctgaatgg acactttttc
    30841 caattataca gattttatta ccttcaacag tatattcaaa atttaattta tcaagttctt
    30901 tttttaattt atcagagtat tttccaatat agattgcttt acctggaact gcatttaaag
    30961 cctttccaac tgacaactct atatcacttt tgctatcaca agtcaaatga acttgtaaaa
    31021 gacctttctc tgcatttgtt attgggaatc tagaatctgg agtaaatcca tagtttggta
    31081 tttcttcatt attttcttta tatttattta tacatctcca aagattttct tcatcagccc
    31141 caaaaatgaa tcttatcctc ttattaaagt ctacatttaa atccataaga gctttcactg
    31201 cataaattgc tgatattgta ggtcctttat catcttgtgt tcctcttcca tacaatttac
    31261 catcttctaa aacagcttca aatggagggt aattccagct ttctaaatca ccttctggaa
    31321 ccacatcaac gtgaccaagt atacctatca ttttttcacc ttgtcctatt tctgcatatc
    31381 cataatatcc atctttgtat actgtcttaa atcctaaaga tttacataag tctaatatac
    31441 ctcttaaagc tttatctaca ttttcaccaa atgggcaatt ttcagttgct tcagatataa
    31501 cactaggtat ttttacactt tcttgtattg aagaaatcat ttcatcttgt agagaattta
    31561 ctttttcttt aatttgctct ttcatattat cacccttcaa ttttcatcat aatatactaa
    31621 taaatatttt gaccttttaa aaaaaaaata tgcttatttt ttcagttttt ttataaattc
    31681 aatcgctttt aaagtcccca tttttgaatg gtcaaatgta agtccacctt ggaaataaac
    31741 attataagga ggtcttattg gagcatctgc acttaattct atagaagaac cttgtataaa
    31801 tgctcctgct gccattatga cttcactttc gtatccaggc atgtcccaag gaacaggttt
    31861 tacataagaa tcgactggtg cagcttcttg tataccttca caaaaactta ttacttcatc
    31921 agcattatta agtctaatac attgaataat atcacttctt aagtcatcat attttggtaa
    31981 tacatcatat cctaattttt caaaagctct tgagcaaaag atagctccca ttacagcctg
    32041 agatactata taaggcgcca agaaaaaacc ctgaagtaca tttctagttg ttccaaaagt
    32101 aagaccacat tcttttccta ttccaggaga agtcattcta taagatataa gctcaatcaa
    32161 atcttttcta ccagctatat atccacctgt caatgcaagc ccaccaccag gattttttat
    32221 taaagagcca gccataacat ctgctccaac atcagtaggc tctttggtat ctaaaaactc
    32281 accataacaa ttatcaacca ttactatagc ttctggttta acagacttta ttacttctat
    32341 agcttctttt atatcactaa ttgaaagtga ttttctccaa gaatatcctt ttgacctttg
    32401 tatcataacg agtttagttc tatcatttat tttgctttta attccttcta aatctaagtt
    32461 tccatcctct aaaaaatcta catcatcata tgtaacacca tactctttca atgaaccttt
    32521 ttcttctctt atgcctataa ctccctctaa agtatcatat ggtctaccag taacagataa
    32581 aatttcatct cctggtctaa ctataccttg tatacataaa gtaagtgcat gtgtaccatt
    32641 tacaattatt ggtcttacaa gagcatcttc tgtattaaat actttagaat aaatttcctc
    32701 tattttttca cgaccaatat cattatatcc atatcctgta gtccagttaa agtgcatatc
    32761 acttagttta gattcttgca tagcttttaa aactttatat tgattatatt ctcttatttc
    32821 ttttatttct tcaaacttat cttttatttc ttccattatt tcttgtgata gtttaaaagt
    32881 atcatcatct attccatagt agtcttttaa taattctttt gtctcattaa gcattttatc
    32941 acctgtctct ttattatttt atttaaacat gtaaaggaga ctattttact aaaacaaata
    33001 aattatagtt tataagttag tataagtctc ctctcaatca tcttaaatta aattaattat
    33061 ctatctgttg ttattattat tgttgttttg gttttgattt gttagattaa tatactttcc
    33121 aggttgtata gttgatacag catgtttata aatcatgttt tgttgtctat tatccccttc
    33181 tattaatatt atataactat caaacccctt tacaagccct ttaacttgca ctccattaac
    33241 taaatatata gtaacaggta tcctttcttt ccttgcatta tttaaaaaca aatcttgtaa
    33301 atttaaaact gtatttttca ttagatttgt accctcccaa gattaaattg aacttctaaa
    33361 atattcctac cttatattct atataagtta tgacaaattt tcaatattaa gttgtatact
    33421 taaaaattta tatattattt tatagaatct ttaatatata agattatttc attttttaat
    33481 tcgtctatat tttcatattg gtctaaatca aaccattttg ctgttttata tcttttaaac
    33541 catgttatct gacgttttgc ataccttcta gaatctcttt taattatttc aatagcttct
    33601 tcgtatgtat attctccatc cagatacttt aatatctctt tataacctat accttgcatt
    33661 gatatcatat cttttttaaa tcccatactt aaaagttttt ttgcctcttc aaccaatcca
    33721 tttttaatca taatatcaac tctcatattt attctttgat acaaatgttc tctatctcta
    33781 tttagaacta ttattattgg ttgatattct tcattaaatt ttaaatcact tgaaaaatca
    33841 ttcattttct taccacttag acaaacttca agagctctta tgaccctttt agtattgttt
    33901 ttatggattc tattagcaga ttcttcatca agttctttta acttattatg catgtaatct
    33961 attccctttt cagcaagctg tttttgaagt tcttctctta attcattatt ggcatcagat
    34021 tgtgcaaaat ccatattata tattaaagag tttaaataaa gtcctgtgcc tccagttact
    34081 aaaacacatt tttccttttc atttatttca tgtatatatt tttttgctct ttgttgaaac
    34141 tctgaaactg aaaatggata gtcaggctta acttcatcta taaggtaatg cttcactcct
    34201 tgcatctctt cctctgtaac ttttgcactt ccaatatcca tatattcata tatttgcata
    34261 gaatcagctg aaattatctc tgcattcata tcttttgcta attttattga caaatctgtt
    34321 tttccaacag cagttggacc tgtaagtatt ataagtggta tttttttcat aacattcctt
    34381 tccatatatt ttaaatatcc aaatatttta cataattctt ttaaacattt tttctatttc
    34441 tgtcttagat atttcgacca ttataggtct tccatgagga catgtaaatg gattctcaca
    34501 cttttctagc tgttccaata aactttttat ttcaatatcg tatattttat catttgcttt
    34561 tatagcagac ctacatgcca tagatgcaaa tctctctcct tttaaatcat aattacttgt
    34621 aatttcttct atattatcaa ttatttgaag tataaatttc tcagtttcag gtactccaaa
    34681 tatagtagga acacatctta ccattatatg attattgcca aaaatttcta gctcaaaacc
    34741 aaatttcata aataactcca agttattttc aatttgaagc atatctatat ttgatacttc
    34801 aataaccact gggtctaaaa gtatttgcat atttatatct tgtctataga acttctccat
    34861 atatctttca tatagtattc tttcatgtgc agcatgttgg tccaacaaat acatagaatc
    34921 gtctttgctc aaaattatat aagtattaaa tacaactcca attacaaaat atccgtataa
    34981 agaaaacttg cgttttgaac tacacaagta ttcttcttca ctgtccttaa tactatctcc
    35041 taagtaataa tttccttcat ttttaattcc atcaacttga aactcttctt gtatattatc
    35101 atttgcacta tcttcactta gataattaat gttttttaca tcatcttcta cacttgcatt
    35161 taggacttca cttactgatt gaaattcatt tattggtttt tcacttgata aagtaacaac
    35221 ttcaatgact tcatccttac ctttagtaat attactattt ttaggagtag attctaataa
    35281 atcattattt cttaatttat aatctgtact tttttctcta ctgttaatag cgattctagg
    35341 ttgtgttttt ttatcactat aagtagcata ttttccaata agatttgagt gtattaattt
    35401 aacctttaaa aaatctctaa gttctatata cacttcttgt tctttttcaa atttaatttc
    35461 aagtttattg gggtgtatat ttacatctat acatgatggg tctacttcta tatttaagaa
    35521 gcacactgca tgtttaccta ttggaattat agacttataa ctttctgtta ttgcatctat
    35581 gattatttta ctttttacaa atcttttatt tatatagata tgttgtaagt ttttatttga
    35641 acggtatata ttgttattac ctatatatcc attcatttta aagtgattgc acttaaactc
    35701 tacatctatt atattttccg ttatttcttt tccatatata cttctaatag tgtttacaag
    35761 ttttccatcc cctggagtat ttagcatctg tttattgtta tttgtatatt taaattgaat
    35821 gtttggatta cctattgcaa gtttatttat caaatcactt atgtttatag tttctgcatg
    35881 agtagatttt aaaaatttct gtcttgctgg tgtattaaag aaaatatctt ttataatgat
    35941 ggtagttcca ttagtagaac ctattggttc tttcgatatt atttttccac cttcaacata
    36001 tattttagtt cctattattt catctttagt tttagtcgtc atttctaatt ttgatacagc
    36061 tgaaatagat gccaatgctt ctcctctaaa accaagagag tataaatcat acaaatcatc
    36121 aattttttta attttactag tagcatgtct caaaaatgat ttttcaactt cacttgaagg
    36181 tattcctatt ccattatctg taatcttaat tagacttttt cctccatcaa ttatatctat
    36241 ggaaatttta tttgcacctg catcaatgga gttttcaata agttctttta ctacagaaga
    36301 aggtctttct acaacttcac ctgctgctat cttatttata gtcaaatcat ctaggatgtt
    36361 aattatattt ttcattttta cacctctaag attttatttc ttttgctttt ctttgaagat
    36421 tataaagaga gtttatagca tctaatggag tcatatttaa aatatccaga tttaaaattt
    36481 cttctgatag tatatctcta tttacactat caaaagagat ttgagttaag gctacttctt
    36541 ttacagaatc ttcttgatta attttctctt tatcatcatt ttgcttcatt aaagcaactt
    36601 catcatttaa tgctttaaat ttagaattta atttatcata atcctttttt atatgtttgt
    36661 agtcttttac tataagttca tgttctattt ttagagattc atatttattc ttaaaattac
    36721 tttgatttac cttaactaat tcttcgtcca aattactatt aattatatta ttgttttctt
    36781 tatctccatt tattgcaaca ctgttgtaaa catgattttt ttccaagtct ttaagtatat
    36841 attttgctct ttctatgact tcgtctggta atttagctaa tttagcaaca tatattccat
    36901 aactcttgtc tgctccctga ggaattattt ttcttaaaaa tattattcct tccccatctt
    36961 ctttgactgc tattgaataa tttttaacct ctttaaactc ttcttctaaa tcagtaagtt
    37021 catgataatg tgttgcaaat aatgtcttac atctaatatt tttttgaata tattccacta
    37081 ttgaccatgc taaacttata ccatcatagg tactagttcc acgacctatt tcatctaata
    37141 taactaaact tctctctgtt gcatttttta atataaggga tacttcgttc atctctacca
    37201 taaaagtaga ttgaccttga gataaatcgt cactagctcc aactcttgta aatattctat
    37261 ctaatattgg aatatcagca gactctgctg gtacaaatga gcctatatgt gccataagag
    37321 ctattatagc agtttgcctc atatatgttg atttacctga catattagga ccagttatta
    37381 tgttaataat gttttctcca cgatttaaat aagtatcatt tggaacgaaa ttttcctctc
    37441 ctactatatt ttcgacaaca ggatgtctac catttcttat atcaagttta ttattttcat
    37501 ttattgctgg ttttacgtag ttatttatat gtgcaactgt tgcaagggac acaaaaacat
    37561 ctatattagc tatagtctta gccacttttt gtattctatc tatgttttta tatattgtat
    37621 ctcttatctc tacaaatatc tcgtattcta aagatttaat cttttcctct gcatgtagta
    37681 tcttttcttc tatttccttt aattctggag ttatatatct ttctgcatta ctaagtgttt
    37741 gctttcttat atatgtctca tctagctttg cctgtttaaa gttggctttt gttatttcta
    37801 tataataccc aaaaacttta ttaaatccta tttttaatga tttaactcct gttttttctc
    37861 tttccctgtt ttctatttcc tttacaagaa aggctccatt cttagaaatc tctcttagtt
    37921 ccttaagttc atcactaaaa tctgatttaa ttatgtttcc atcttttatg gttatcgtag
    37981 gttcttctag aatagcttca tctattaaat tgtatatatc atctaattta tccatttctg
    38041 aaacatactc ttttaggatt tttgcatttg ataaatttat agtatctttt aaattaggta
    38101 acttttctat cgaatttttt aagtgaatta actcttttgg tgttactctc tcaaatgcta
    38161 tctttccaca tattctttct atatcgtata tatttttaag tatatcattt aggtcttctc
    38221 ttaatataaa gtcatctttt atttcttcta ttacatctaa tctattttca attttagatt
    38281 tatttatcaa aggttcttct acatattttc ttaaaagtct acctcccatt gctgtagaag
    38341 ttttgtcaag tacatgtaat aatgaacctt ttttcttatt ccctcttata gtttgagtaa
    38401 gttctaaatt agttctagta aacatatcta gaaccatata ttctgatgaa ttgtatatat
    38461 ttatattatt aatgttagat gttatttgtt tttgagtatt gtatatataa ttcagaagaa
    38521 ttgataagct tgactttatt agacctttat catcaaactt tagtttttgt agataaacat
    38581 ctggaaaata ttcttttaat atatttatat ccaaatagtt atcactaaaa ctttcattta
    38641 tgtatatatt acttacagta gctatatctc taagcttttc tataaagtct aaatcattta
    38701 taattatttc agttggatgg atttttgcaa tttcttcaat taccttatct tcatttaaac
    38761 atgttgcatt agtttctcct gtacttatat caacataagt tagacctata ttagtaccat
    38821 ccttatacaa agataataaa taattattct ttttattttc aagtaaattt ccatctaaaa
    38881 ctgtaccagg agtgatgacc cttataacct ctcttctaac aattcctttt gctgtagatg
    38941 ggtcttccat ttgttcacct attgctactt tatatccatt ttcaactaat tttgatatat
    39001 atgaattggc tgagtggaaa ggaacaccac acataggagc acgttcttct aaaccacaag
    39061 cttttcctgt caatgctatt tcaagagctt ttgaagctac taatgcatct tcaaaaaaca
    39121 tttcataaaa atctccaagt ctaaaaaaca gtatacagtc tttatatcta ttttttactt
    39181 caagatactg tttcatcata ggagttaatt tattcatatc tatttgcatt atcaaacctc
    39241 cttcttttct aattaaatat tatatcatag tagatgatta ttattaacac aatatataaa
    39301 attttgacat ataactaaaa acaatccaaa atgtatactc acattttgga ttgctaagtt
    39361 taatgcttat taaataaaaa tatttttttt tacaataaag atattatttc ttttttaagt
    39421 ttaatgatat tttcaaggtt atcttcattt aactttctac tatctataac aaattctttc
    39481 tttactattg atggtttttt tgaaataaca taaattctgt ttgatagcat tatagcttcg
    39541 tcaatatcat gagttataag aagtattgtt gaatttactt ttttcttaac atctaaaagc
    39601 catttttgca tggatgtttt agttaatgaa tcaagtgccc caaaaggctc atctaaaagc
    39661 attatgtcat tagaatttat aaaagttctc aagaagttag ctctctgtct cattcctcca
    39721 gaaagttctg aaggatattt atcttcatat ccgcttaatc caaacacctc aaaataaggt
    39781 tttaccattg acctagcttt actctttttt tcttttttta aaattagtgg tagtgacaca
    39841 ttatctatta tagttttata tggcaagagt aaatcttttt gatacatata actatactta
    39901 ccatttatat tcactttgcc actatcataa tctgtaagtt tagttataat attaaaaata
    39961 gtactttttc cacatccact tggccctaat atagaaacaa actcaccttc ataaacatca
    40021 atacttatat cttttaaaac ttcaatatct ttataagttt ttgatacatt ttctatagat
    40081 acttttactt ttttattgtg gtaaaaattc atttgtgtaa gcatcacttg ccttcatatc
    40141 cttatctatt aatttatatt cttttaagaa tgatgtatag ttgttccata cactatcttt
    40201 catttctccc catcgtggtg catcatcttt gtacttgctt gctaaatatt cttgactctt
    40261 taaagctagt ttttcatcta cttcaggtgc atgttttact aaaatttttg ctgattcttc
    40321 tggatttttt attgcatatt cataaccttt tgttgtagct tttaagaatt ttttagcaag
    40381 ctctggatta tttttaagca cagtttcatt agaaattata agtggtgtat aataatccaa
    40441 tctctcatct aaatctttta ctggtataaa gtttaagtca tatccaatta aatcagcttt
    40501 aactgcatcc caaccttcaa atatccatgc aaaatctaca gttttcatag ctgcaaagaa
    40561 atcatcttga ccagtattaa ctatctttaa cttattaaaa tcagctccat ttttcttcat
    40621 aactgcttta aaaacagctt cttctgatgg agagccccaa ccaccataag tttttccttc
    40681 aaaatcttta gctgttgtta tattcttttc ttttggtgat gcaaacccag aagtattatg
    40741 ttgtataaca gttgctacag cttttattgg aagtggatct tcactagtct ttgcataagt
    40801 aacttgttct tgatagctta taccaaagtc agcttttcct gttgctacta aagtttctgc
    40861 tccactttca ggtggttgta ctatttcaac atccaaacct tcttctttat agtaaccctt
    40921 atcaagtgct acaaataatc cagtatgatt tgtatttggt gtccaatcaa gcaccatagt
    40981 tactttttta gaagaagtat ctttatcatt gtttttgtct ttattgttat ttgaagaaca
    41041 tccagttatt gttgccaatg taaaaacact tactaaacct aatattccta actttttaaa
    41101 attcataatt gcctccctca aataccctta atctattaat ctatgtctta taacaacttt
    41161 ttttacagcc tgtacaattc ctacaaacat taaactaaat ataactacta atatagtaga
    41221 tgcaaatact ttatcaagtg catatgcact ttttgaccta agcatataaa caccaagtcc
    41281 tttcgttcca cctagccatt ctgcaacagt tgctgccatt acagcatacg ttgcagatat
    41341 tttaagtcca gaaaaaaatt tatccattgc cataggaaat ttaaggtgaa tgaatgtatt
    41401 aactttattt gagtccatag tcttaaataa atttaaataa tctttatcaa tattctcaat
    41461 gccatctaca aaacttatta atataggaaa aaaacaagta agcattacca tcaatacttt
    41521 tggcattgtt ccaaatccaa accatatcat aaagagtggt gctataatta ttgtaggtat
    41581 catctgtgta accaacataa taggataaag acattttttt attattgata caaaatccat
    41641 caatattcca attaccaatg atattataat tgcgactata aaaccaagta ttgcttctcc
    41701 tatagtaacc acagcatgta tggataaatt ttgataatct ttaaaaaaca cattaattat
    41761 atctactggt gtgggtagta tatactgagg aacttctaaa actcctacca tagattgcca
    41821 aagaataagt ataaacaaaa atgttgctat tggatatata ctatctttga ctttatctat
    41881 gatttctaag tttttcatct atagtcagac ctccagcttt ttcatctact ctagctactg
    41941 ttatgactct ttcacatcca agattaaaag ggattttatg tacctttttt aataattcaa
    42001 aaacttcatc aaaatcacct tcaacagtag tgctcattgc tcctatttca catttaagac
    42061 cacttttttc aatttcagca atacaagcat ctactacttt atacatctct tcttcacctt
    42121 tgtaaggtct tagtggcatt actgctatgt ctgcgattac catttaaatc actcctttaa
    42181 aaataattaa tacctactag gtatattttg ttttttatta aaaaatttta ttactaaaaa
    42241 gatattatat ttaaataaaa gaaaagtctt atccaaaata ggataagact tatttttatc
    42301 ttaactggtc tccctacact ggcattatcc aaacaggttc aaagggtcga gataaaatct
    42361 cctctcagca cattagctcc ccgaaatata ttatatcttt tctacttgat tatactacac
    42421 ttatcatatt ttaacaaatt ttttatttat attagatatt ttatccgttc aaaaatatct
    42481 aatataaatt gtacattatt acaccaaata aattatctta aaatggtaat ttatcaacat
    42541 cttccaaaac tagattaact gaattttcta gtttttattt tgctatttca agcatatttg
    42601 gatgtatatc aattccatac aaatattgtg ctaaatttct gttttcactc atctaatttg
    42661 caatcgttac aaattacaga ttagaaatag cttttagact ctacttatct ttatctacaa
    42721 aaaatccttc aataaattca ttaataatat tcagtaatct aaaaataaac ctctatctag
    42781 atttttaaga tacaagcctt ttaggaagta tcttttgtga taatataaaa attactcatc
    42841 attatcatca aaatcctcag caaccaacat tttagataag aatcaaactc tataatataa
    42901 ttattttatc caatttattt ttgagaaata aaatattttt ttaattttta aattttttaa
    42961 tatgcacctt gaaaaaagaa acgttttcct atattatggt aatagtagaa taaaactaaa
    43021 taggcaaaac tagagaaatt tagtgacgca aagctatagg gactaagact tatgaaatga
    43081 gttatgtcag ccagttgcca aagagatatt ttctttttgt ttttatgaat gttttttagg
    43141 gggatatatg atatatgttt atggataaaa tggatagatg tacacatata ctaactgcat
    43201 atatatgcag ttcacgcgat tactgcaatt ttatagatac acaattaaat gattttatac
    43261 tagaatatgg agagaatgtg gtagaatctt gtttgcatca agtgatggta ttggtaagca
    43321 gatataatta aagaaatttt attttctaga aaaccctttt tagttttatc tacgttttat
    43381 aattcattaa agaactaatt aaaataagct tcattatata tttttcataa agtaaacagt
    43441 tgagtttatc tcatatactg tttaccccaa ttacataatt ctaataatat agattctaat
    43501 gatttaccac gtttagtaga caaatattca acttttggag gaatagtcgg ataagaaatc
    43561 ctcttaataa gtccatctct ttcaagatac tttaattctt gtgacagtat cttatgactt
    43621 atatgaacaa cttctttttt taattgactg taacgtattg gctcttgttt taaaatatgc
    43681 cataaaataa ttgccctcca tttacttcct atcacagtca tggtaaaacc aattgaacaa
    43741 ttaaaatctt tttgtctttc ttcaatattt ggaaattctt caaaattatt atctatatcc
    43801 atctcaatcc tctctttcaa aatagtaagt atctaactaa aaagtgcatt cttgtttagc
    43861 gtactaattc gtaatataat cttgattgta gtatagagcc ttacataata ctactttttt
    43921 agatgtatat gtttaaactt taatatagac atatgttatt ttattaattt tatttaaaca
    43981 gataataata aataataatt tatctcaagt tttctatgta gataaactaa tctaatgttt
    44041 agaaaggatt atataatatg aataaaaaat ttcgtcttta tcaagttgac tcattacaaa
    44101 agaaaaattt acaggtaatc cagctggtgt aattacaaat gctgatggct tatctgaatc
    44161 acaaatgcaa aaaatagcaa gagaattaaa taattcagaa actgctttta ttttcaataa
    44221 cttggctaaa aatcatcaag aaaattatga tgtacatatc agatttttta cactaactaa
    44281 tgaggttcct atatgtggtc atgctactat tgctgcccat tatgttagag cagtagaaaa
    44341 ccaattcaat aacaaaacag tatttcaaaa aactagtgct ggaatattac cagttgatat
    44401 tataaaaaaa gataatgatt atgaaataat tatgacacaa ggaaaaattg aagtatctcc
    44461 accgttacaa caaacctatc aaaaaagatt acttaatgca tttggtattt taaaggaaga
    44521 tattcgtaca gattgtccta ttgccatatc atctacagga cattcaaaag ttatgattgg
    44581 aataaaggaa ttatcaacat taaatagttt atctccaaat ttatatgaat tatcgaaaat
    44641 aagtcaagaa ataaaatgta atggatatta tatttttaca ttacataata aagaaactct
    44701 acaagttcat ggaagaatgt ttgctcctgc aattggtatt tcagaagacc ctgttacagg
    44761 aaatgctaat ggacccttag gtgcgtacct tgtacattat aaagtaatac ctacacccaa
    44821 cacagagttt atatttgaag cagttcaagg agaaacaata aaacgcaaag gcaagatgtt
    44881 agtaaaagta attattttag ataataaacc agttgaagta aaaataattg gaaaagctgt
    44941 aattgcattc tcaacaaaca tagaaatcta attatagatt ccttctaagt aaatttttga
    45001 actttttaat actaatttaa taacaaacta atttatatac aatcaaatta atttttttat
    45061 tatttgttaa tat
//
LOCUS       DAMKNB010000028        43328 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.029, whole genome shotgun sequence.
ACCESSION   DAMKNB010000028 DAMKNB010000000
VERSION     DAMKNB010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 43328)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 43328)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..43328
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.029"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            complement(84..2039)
                     /locus_tag="PC494_001687"
     CDS             complement(84..2039)
                     /locus_tag="PC494_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3912190.1"
                     /translation="MKKYEIFIFMSIIVLCFISFPHKVFGQEENCLEDFERWVQENKN
                     NKEEIVYTLSCDMVIDEEFRFYIPYDSNFTIDTNKYKILIKNHGRFIIDDNELNITGE
                     GGKEGVIHIENGGSISIGINNIIATDGTALYVEEGGDLHIKSSYESVEKIKANGKDAI
                     GIYTENDIRILNKNIEVNGEHAIGVYSKGDVEIEETSIKAYSSNNESGLLKDNNKLAQ
                     SIISESKKVYIIDDYNELIPSIAEDSGYDIVKCCHRGIDVFSDEIKVSKDDKIENIKF
                     PKYMVLETSSGNRLDIDVEWDFTDYYEKLEKGEDFNITGKFKTEMLNKEKIIINDDVV
                     PSLNVSVIEKKPIDNLELEFQNTKNGYVAVLFYDMPYSASKVFVEYSSDGINWISEEQ
                     EDIRDQAILFFEDFKLRCFRVKVVGGLKEGYSNIVFKPGFIMGGGDNQETPDDEREND
                     DIDGDRGGGGRDDPDRDEDDNNQDGNNGNENNDSNNNQNNNNENNNNENDDSDEKQPN
                     TPKDDVESSTDSNENKNPHDIPKDGNKENNSDKEKGFYNKNSITENDDNYDLSSKSVF
                     GTNEHSFPYRESISNKNQDTNKNKSNISDYDGIINNNYKLESKEYNLKKDIIFLFCIL
                     TPIMIGSILIVNPDTRKSIIKFIKLKK"
     gene            complement(2222..3697)
                     /gene="spoIVA"
                     /locus_tag="PC494_001688"
     CDS             complement(2222..3697)
                     /gene="spoIVA"
                     /locus_tag="PC494_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage IV sporulation protein A"
                     /protein_id="HDF3912191.1"
                     /translation="MNNNIYEDISKRTQGDIYIGVVGPVRTGKSTFIRKFMEKLVIPN
                     IDNEFKKDRTRDEIPQSGSGKTIMTVEPKFVPADGVEIKIKDTVSLKVRMVDCVGYIV
                     EGALGHEEGGKQRLVSTPWSQEAMTFEKAAEIGTKKVIKDHSTIGIVVLTDGSVTGID
                     RKSYVEPEERVIQELKNLKKPFAVVLNTLSPKSEETSMLRSELEEKYEVPVLPMNVVE
                     MEEEDIEEVMEAVLYDFPLTEIRINLPKWVEGLERNHWIKSSIITTLKQSIIDIGKIR
                     DIEGIIQGFSELEFLEDTGVDNVELGEGVINIDLQTKQDLFYNVLEEKSGFKIEGDYQ
                     LLSLITRLSKVKNEYDKIESALIDAKIKGYGVVAPSLEELSLEEPEIMKQGKQYGIKL
                     KANAPSLHIIKADISTEVSPIVGNQNQGEEMIKYLMEVFEEQPADLWESNMFGKSLHD
                     LVKEQLQSKLYTMPEEIRVKMQKTLQKIVNEGSSNIITILL"
     gene            complement(3869..5163)
                     /locus_tag="PC494_001689"
                     /pseudo
     CDS             complement(3869..5163)
                     /locus_tag="PC494_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903280.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
     gene            complement(5347..6756)
                     /locus_tag="PC494_001690"
     CDS             complement(5347..6756)
                     /locus_tag="PC494_001690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HDF3912192.1"
                     /translation="MKKKIGFWDLVFMNISALFGIRWIAKSTASSFGLGLGSIPVWLL
                     FAFIFFVPASLICAELAATYPKDGGLGEWVKQAYGEKWGFMVSWLNWTSKIFWYSSFL
                     TFLAINIAYMLGNPDLSNNKMFILALSLIIFWLLSLVSTRGMAFGKFFTNTGALGSTI
                     PAILLIVMAFMSVVILKKAPSASIYTIQNIIPKIDANSLVSISAIIFALSGAETTANF
                     ITEMDNAKKNFPKAILTVAVLIGGIYILGSVAITMILPPDKIAASTGILDALAKVAQD
                     LGIGSWFIRIVAFGITLSVLGALILYIAGPVKMLFGNVREGVFPKQLTVTNKYNIPSN
                     AVIVQAIIVSLLLVGTNLLPSVDNIYNVLVTMTALTALFPYVLLFTSYIRLRKTRPNE
                     ERPYSIAKSDSVCINIARMVLVVTVVGILFSTAPVMETLKDNIIYEIEMIGGGLFVII
                     TGLMLWKNYEKKISNNSGC"
     gene            complement(6808..7947)
                     /locus_tag="PC494_001691"
     CDS             complement(6808..7947)
                     /locus_tag="PC494_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HDF3912193.1"
                     /translation="MSNNMRLERLRKYMNEKSIEIALIFEPDNQFYISGFKAITYSRP
                     IVTVVTQDKIELIVPGLEELHAKEVAKVDNVYVYYEIPEMKEHGISHKHYLDIILNKY
                     PKGTTVGIEKDIVSASFSEYITDKSFAIKDVGSKIFEMRYVKDAKEIEFLKIAGYLSD
                     IGIKGSLENVRVGMSELEFDVAGDNALLKYVSENYPDTYIGFANWTCSGIDRTAQPHL
                     DSNTRILQRGDIVIHSRQVWYENYRAENERTFIIGKPTERQKEVFKIAVEAQQAGLDT
                     IKAGIPARMVDEAARAVVAKYGLELYSNHRIGHGLGLSEHEEPYLRFDNELILEEGMV
                     FSMEPGIYIPGVGGFRHSDTAIVGKNGATIITNYPRSVEELILDI"
     gene            8266..8916
                     /locus_tag="PC494_001692"
     CDS             8266..8916
                     /locus_tag="PC494_001692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDF3912194.1"
                     /translation="MTNKELQKKRILMYFIEAAQNIMENEGIENITLRKVADMAGYNS
                     STLYKYFKNLDHLISFASIKYFKDYNLNISRCIENVNDEYKKYIIMWKLFCKHSFDNA
                     QAFYQVFFNLSSDELSYITKQYYDMFPEDLGIHDSDISLMITGESIKERNKILLNNLV
                     DTGYIPAKDLDIINDIIISFYQNLLFLKKNTGKNSDDDELTMKMISSIEYIIKHAK"
     gene            complement(9073..10092)
                     /locus_tag="PC494_001693"
     CDS             complement(9073..10092)
                     /locus_tag="PC494_001693"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HDF3912195.1"
                     /translation="MEKVCVLGTGSWGSALALGLAKKGNDVSMWTRKEEQAKKINRTK
                     ENTDYLPGVLFPNNITISTDIEKTIKDCKVIVLAVPSQAVRSTCQKIKPFIKEGQVIV
                     NVAKGLEKGTGLRLSQVCEEELPQNPYVILSGPSHAEEVARDIPTTVVVASKDLKIAQ
                     MIQDLFMSPKLRVYTNPDIVGVELGGALKNIIAFGAGICDGLGYGDNAKAALMTRGIS
                     EMSRLGIAMGANMSTFAGLSGIGDLIVTCTSMHSRNRRAGILIGKGMSLEDTLKEVKM
                     VVEGITATEVAHDVAEKLDIDMPITNAIYSVIKKGSNPKEVGIELMMRSKKHEMEEVV
                     LGDDI"
     gene            complement(10123..10737)
                     /gene="plsY"
                     /locus_tag="PC494_001694"
     CDS             complement(10123..10737)
                     /gene="plsY"
                     /locus_tag="PC494_001694"
                     /EC_number="2.3.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HDF3912196.1"
                     /translation="MEIFSYIIIAVVAYLLGNISTSYIVAKRIAGVDIRTQGSGNAGS
                     TNVLRTLGKRAGAMTFLGDVLKGVMAVLISEFAARLVGIDTLLAGYLAVICVVAGHNW
                     PAVLGFRGGKGVATSLGAMLAVNPVITLMCLAVFILVVAITKYVSLGSVVGIGCSPIF
                     MIMVKNKAGLIVALFLTASVIYNHRANIKRLLNGTERKIGQKKE"
     gene            complement(10772..12091)
                     /gene="der"
                     /locus_tag="PC494_001695"
     CDS             complement(10772..12091)
                     /gene="der"
                     /locus_tag="PC494_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012063975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HDF3912197.1"
                     /translation="MSRPVVAVVGRPNVGKSTIFNKFAGKRISIVENTPGVTRDRIFA
                     EVEWLDKYFTLVDTGGIEPDSEDIILSQMRNQAMLAMDMSHVILFIVDGKAGITAADK
                     EIAQLLRKTKKPVILVVNKIDSQSQFDNIYDFYELGFGTPFAVSGANSMGFGDLLDEI
                     VENFPAGLDTEYEEDIIRVAITGKPNAGKSSILNKILGEERVIVSPIAGTTRDAIDTY
                     FEKNGQKFLLIDTAGLRRKSKIYETIEKYSVIRAMSAVDRADVVLIVIDALEGVTEQD
                     TKVAGIAHDEGKGCIFVINKWDLIEKDNKTMSNYTKDIKEKFPFMMYAPIVFVSAKTN
                     QRMNKILDTVEYVSNEHSKRISTSALNEVIGEAVMLNQPPSDKGRRLKIYYGTQTDIR
                     PPKITLFINDKDLTHFSYQRYLENKIRENFGFEGTSIKFEYRQKNKK"
     gene            complement(12125..13453)
                     /locus_tag="PC494_001696"
     CDS             complement(12125..13453)
                     /locus_tag="PC494_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF512 domain-containing protein"
                     /protein_id="HDF3912198.1"
                     /translation="MEVNVKKVNNIISKVYKDSIAEEMGIEVGDLLISVNEQPIHDII
                     EYRFLLSDEYLDVEIQKKDGEVYIYEIEKDYDEDLGVEFTNPIIDQAKSCRNKCMFCF
                     IDQLPEGMRETLYFKDDDSRLSFLQGNFVTLTNMSEEDINNIIKYRISPINISVHTTN
                     PELRQKMISNKFAGKLYGIMKRLADAHIEMNCQIVLCPGINDGKELDRTIKELAQLYP
                     YVNSVAIVPVGITKHRENLVELNIFNDKSASKTIEQIHQIQQKYLEKLGTRFAFLSDE
                     FYILSNSELPGYEEYEGFLQFEDGVGMIRKLKTEIEEYLNILPEKILKREKKVSIATG
                     HSAYEFIQSMADAMMDKFKNLQVNVYEIKNKFFGETITVSGLLTAKDLKEQLEDKELG
                     EALYITRSMLKADEEIFLDNIELNQLEELMRIKIIPCLNEGKDFVDKILK"
     gene            complement(13691..13891)
                     /locus_tag="PC494_001697"
     CDS             complement(13691..13891)
                     /locus_tag="PC494_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3912199.1"
                     /translation="MGMDIGLNEYTLAIVTLDKNMKNGGGCPIFYANDEKDLQNKALL
                     MSKCVGGMVHDMTNGTLIIVKH"
     gene            complement(13893..14825)
                     /locus_tag="PC494_001698"
     CDS             complement(13893..14825)
                     /locus_tag="PC494_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YIEGIA family protein"
                     /protein_id="HDF3912200.1"
                     /translation="MDRVFFVAVIIGITSRIIMLNLDQKQYPTQPNVLLSQLILAFVA
                     SSLGALLVPALINRSYTSITFLSLAAEQFRQVRANRRNTLQNLEEVQLVKRGAAFIEE
                     IARTYEVRNYMCIVTSFLTIGLYYVILAETKISEGMSLVISSICGLVLAFILKKLLTR
                     KSIGDIADVMPAEISFVDESILKVGDLKGITNIGLKSDREVYINRGVGIQIIPKNKDY
                     ANAGILFDSGQRQAIVYNIYSRLGLYGDYGEPSFVPLPRRNKEDESIMIAYLPVDKNV
                     EKVMEAVKSCPILSSSKGKNLSLKNYKIGKKGSA"
     gene            complement(14870..15802)
                     /locus_tag="PC494_001699"
     CDS             complement(14870..15802)
                     /locus_tag="PC494_001699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YIEGIA family protein"
                     /protein_id="HDF3912201.1"
                     /translation="MEESLLNANLFRHSFIVALVVGILCRGLVLRVTDKQYPSRPQDY
                     LEQIIISGLSASLGAIALPALIDKEFAALTFFAVAIQQFQGLAEQERITLKNIDNEEL
                     VPKGDAYVEEIASTYESRSYISLFSALVSSIVYIVFARKYGLSFFYCTILAIVSGAIV
                     GLIFRRFLRRNSIADIADIVPAKISFEGPILMVNGVIITNIGLESTREKYRNECLAIE
                     VIPRDLGAFGIVNDIGQRQAIIHNLFIHMGIDRDVDEVDIVAISKTNLEKSTVVIPYM
                     PILKDIDVMIDVVKSTPIIETSKGKQSDFSRKTL"
     gene            complement(15857..17146)
                     /locus_tag="PC494_001700"
     CDS             complement(15857..17146)
                     /locus_tag="PC494_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HDF3912202.1"
                     /translation="MEDLNSIYFFIVMLSIAIVILAVRYTITLRKYLKEFIYVSKKVS
                     NNEYHARLNISAKGELGELARNFNHMIKNMDKTLEEVQYKHLQLRSILKSISHGILAI
                     DVNGNILLINDEAKEMIKSEPNQLVEGHNINVVIKEEEILKQILQFIGSKDNETANIT
                     TKDDIVYKIKVDPVYLQNTNNVIIGSIVNIEDITKKVKLENMRSDFVANVSHELKTPL
                     TSISGFVETLKSNENIDVNTRNRFLEIIESESDRLKRLIDDILLLSFVENKDTLLMEN
                     VVVYDVFKEVYEITQHSASEKNIEVLYKCDDKSISILSNKDYIKQVFLNLVDNAIKYT
                     QDNGIVQVVVLKDEEKIVIKVIDNGVGIPKEDVERIFERFYRVDKARSRDVGGTGLGL
                     AITKHIVKSLNGCIKVKSELGIGSEFIVTILQKNFLK"
     gene            complement(17175..17867)
                     /locus_tag="PC494_001701"
     CDS             complement(17175..17867)
                     /locus_tag="PC494_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF3912203.1"
                     /translation="MNTKVLVIDDEMHIVELLKFNLEVSNYEVSYSYDGFDGFIKAKE
                     IKPDLILLDWMLPNISGIEVLRKIRSDKDLKNIPVIMLTAKNMENDKVEGLEIGADDY
                     ITKPFSIKELLARISSVLRRYNLTSLGEENNILTTGNLKLDLSKHEVTKGSEKIELTL
                     KEFELLKLLIQNKGKVLSRNYLLDKIWGYEYYGETRTVDVHIRYLRKKIEDEDKSEKY
                     IETIRGVGYKID"
     gene            complement(17882..18643)
                     /gene="pgeF"
                     /locus_tag="PC494_001702"
     CDS             complement(17882..18643)
                     /gene="pgeF"
                     /locus_tag="PC494_001702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan editing factor PgeF"
                     /protein_id="HDF3912204.1"
                     /translation="MMKDYINIKNVQDIKEYVNLSGNCEELDEKLNSVNLVITCKNID
                     AKNREDMLKVCKECDLTFENLTSNSQIHSDIVTIVNKDTIGKRRDGDALITNLEKVPL
                     LLFTADCVPISIIDAKNKAIGLAHAGWRGTFSNIGHKTIKLMSECYKTVPEDLVCIIG
                     PSIGPCCYEVSEDLVEKFNTILTNNDEKFYIIKEGSYYLDLWKINEYMLRCSGVKKEN
                     IINLNLCTSCRADKFHSYRKHNKASERIGTVLQIK"
     gene            complement(18640..19101)
                     /gene="nrdR"
                     /locus_tag="PC494_001703"
     CDS             complement(18640..19101)
                     /gene="nrdR"
                     /locus_tag="PC494_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor NrdR"
                     /protein_id="HDF3912205.1"
                     /translation="MQCPYCNYKESKVIDSRHTDLKSIRRRRECESCKKRFTTYEKIE
                     TTPLMVIKKDNSREYFDREKIKYGLLKACEKRPVSIDEIESIVVHIENEINKCFIEEI
                     ETKKIGEMVMDKLKELDEVAYVRFASVYRQFKDINTFVNELKSILIEKGDK"
     gene            complement(19123..19386)
                     /locus_tag="PC494_001704"
     CDS             complement(19123..19386)
                     /locus_tag="PC494_001704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlmC/YmxH family sporulation protein"
                     /protein_id="HDF3912206.1"
                     /translation="MIRVSDIMEKEIINVKNGKRMGFIIDIDMDIHEGKVVSFTIFGD
                     GSRSFFSRGGDEEVIFWNDILKIGCDTIIVNIGSELSLDEFEI"
     gene            complement(19490..20263)
                     /gene="sigG"
                     /locus_tag="PC494_001705"
     CDS             complement(19490..20263)
                     /gene="sigG"
                     /locus_tag="PC494_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011986856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sporulation sigma factor SigG"
                     /protein_id="HDF3912207.1"
                     /translation="MQVNKVEICGVNTSELPVLKNKQMKELLLQIKNGDEEARQQFVR
                     GNLRLVLSVIKKFNNRGENIDDLFQIGCIGLIKAIDNFDLSQNVRFSTYAVPMIIGEI
                     RRYLRDNNPIRVSRSLKDIAYKALQVRERLIRTNSKEPTVSEIAKELELEVESVVMAL
                     DAIQDPISLFDPVYQDNGDAIFVMDQVQDKKDTDENWLQEISLKEAIKKLNSREKLVL
                     DLRFYKGRTQIEVADEIGISQAQVSRIEKNALKNMRKYV"
     gene            complement(20355..21077)
                     /gene="sigE"
                     /locus_tag="PC494_001706"
     CDS             complement(20355..21077)
                     /gene="sigE"
                     /locus_tag="PC494_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sporulation sigma factor SigE"
                     /protein_id="HDF3912208.1"
                     /translation="MLRLKERIISFITMLGIKLKIIKPKGIYYMGGANILPPPLKPEE
                     EMELLQKLETDESVKSILIERNLRLVVYISRKFENTGIDVEDLISIGTIGLIKAVNTF
                     KLNKNIKLATYASRCIENEILMYLRKNNKKKTEVSFDEPLNIDLDGNELLLSDVLGTE
                     NDEIYKIIEEEIDRDLLVMALDRLSDREKQIMELRFGLIDKGIEKTQKEVAGILGISQ
                     SYISRLEKKIISRLQKEMKKFV"
     gene            complement(21102..21974)
                     /locus_tag="PC494_001707"
     CDS             complement(21102..21974)
                     /locus_tag="PC494_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-E processing peptidase SpoIIGA"
                     /protein_id="HDF3912209.1"
                     /translation="MFKGFKGGYMVYIEYYVIENLVINYIIISCTSILTKRYNPKKNK
                     LLGASLGGAYSVAYLYPSMNILFTVPFKIIIMSIITLISFRSKSKKDYVHVALVFYLV
                     NIFISGSTYFIIYFTGISHLKISFLIACTYVSCELLKYIYKDLKMLKYIKELTKTINI
                     NLLEKSFCCKALVDSGNLLKDPISQSDVIIVKSSVLEGFIPEKLLNINYEDIDMKKAQ
                     EIIGSLDDKTSGRVRIIPYKHAGSNKTSIIIGLKADYIEVDEQKIGNIILGISNFNDR
                     EYGAIMNPNILPGF"
     gene            complement(22264..23538)
                     /locus_tag="PC494_001708"
     CDS             complement(22264..23538)
                     /locus_tag="PC494_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HDF3912210.1"
                     /translation="MIKLKKVLSLVMVGILSVSILAGCSKKEDSKGKEGKEKLVVWSA
                     PLTDHDADAWKPIFEKFEKENNCEIEFQIVPWDNYAEKYATAISAGEGPDIGYMYAEM
                     FPQFIEMGAVEDLTPYLEKSGTSDNYLYLDDAKMMGGIYGLPIEAANPGVLYYNKDIL
                     EKLGEKPPKTWDDFKRICEKATKDTDGDGKIDQWGLAQGWGSKVFGSLNWNWYPYLWQ
                     AGGDIYNDDLKSVKFNNAEGLKAANFINDMKKYIPEDALSKDSNEMIESVFGPGKAAF
                     TIMLSSAATSTFDKSFPDLNWGYVTSLEDKTVGSFASVDDLTLMSACKNKELGFKLLE
                     YMLSKESMEAFHKEIPRAPVAKGEKYQGDPRFEEMVTRDKHMYRPLTVGPHGVEIYEY
                     LWKQLQMMIAGDITPEQALNESAKYANGLLAQ"
     gene            complement(23822..24979)
                     /gene="ftsZ"
                     /locus_tag="PC494_001709"
     CDS             complement(23822..24979)
                     /gene="ftsZ"
                     /locus_tag="PC494_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HDF3912211.1"
                     /translation="MLNFDVELEECAQIKVIGVGGGGNNAVNRMVEAQLKGVEFISVN
                     TDKQALYTSKAEYKVQIGEKLTRGLGAGANPEVGKRAAEESKDEIVKLLQGADMVFVT
                     AGMGGGTGTGAAPVVAGLAKEMGILTVGVVTKPFAFEGKIRMKNAEGGIAELKSKVDT
                     LITIPNDRLLQIVQKNTSMLDAFAVADDVLKQGIQSISDLIAVEGLINLDFADVTTIM
                     KDKGLAHMGIGSASGETRAIDAARQAIQSPLLETSIQGAKGVLLNVTGGPNLGLFEVN
                     EASTLVMESCDPEANVIFGASIKEDLGDEIMITVIATGFEGLQNGALDLDTKPKSSIR
                     SSLNTTVKQAVKEIEEEVIAEEKIEPPKKASIIEEDDDESMEIPTFLRRRR"
     gene            complement(25169..25522)
                     /locus_tag="PC494_001710"
     CDS             complement(25169..25522)
                     /locus_tag="PC494_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="small basic family protein"
                     /protein_id="HDF3912212.1"
                     /translation="MLWVLGGLAFGVVVGYYIPFTYSMDYSIYMSVAILAIMDSIFGA
                     IKSNFEDNYDNVIFITGFIGNAILAILLTYIGEKLGVSLYYVAVLVFGMRLFNNLSII
                     RRYIISNIMNKKRKN"
     gene            complement(25621..26295)
                     /locus_tag="PC494_001711"
     CDS             complement(25621..26295)
                     /locus_tag="PC494_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF881 domain-containing protein"
                     /protein_id="HDF3912213.1"
                     /translation="MKKKIVILGAFILGVFISTYIKSLDPNRVYITLGQTESIESEVE
                     NTKKEIKNLKETLKKNKKTLNEYKEAKKNGNESIQTLMQKELEEVKELSGYSTVTGPG
                     ITITMRDSERELKDGQNPNDLIIHDIDILRVLNDLKKAGARAISINGERVLATSKIKC
                     SGATITVNDTTYGQPFIIKAIGDIDLLSAAINSPESYAKSLKDIYGINIKVQENNGNK
                     VNLFAK"
     gene            complement(26300..26998)
                     /locus_tag="PC494_001712"
     CDS             complement(26300..26998)
                     /locus_tag="PC494_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF881 domain-containing protein"
                     /protein_id="HDF3912214.1"
                     /translation="MKKRFINKSIIIGSIVLGVLVSLQLKIINIENRGMTTFKRGEQL
                     TEELKSLKKEKENLQSEVNSVKKDIETYRGKNNEGEQDILKSEIEKYETLAGYTDVEG
                     TGIKIEINSTKDLGNSDKNDSILYNYDLLLSMINKLNSAQASAISINDQRIVSNTYMY
                     LKEDKLYMNDTVIKEPIIIKAIGDSDTLASALNIKYGIVWEIETYYNAKVKVTKEDNI
                     EINGHSDINKAEGK"
     gene            complement(27021..27761)
                     /locus_tag="PC494_001713"
     CDS             complement(27021..27761)
                     /locus_tag="PC494_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsQ-type POTRA domain-containing protein"
                     /protein_id="HDF3912215.1"
                     /translation="MKKRRKLNTNNVMIVLVFILMLSFCICIIVKSDLFDVKKIDVIG
                     NKRVTKSNIMKELNVNLNENIFAYNFKDMKNKLIKNPYIENVEIKRKLPNKIIISLKE
                     KEIFAVLKDEDNYCYIDKKGNLLEELRGSNESKKDLIVDVDYSIDDNKSIKFKNYKTK
                     ENVFKTLNYLKEEGIYRKINYVNLKKESNIEMLTRSNIKILLSNDDNLDYNISRVSKI
                     LIDLQNKNTNGGTINLNYGKLAVYSPEG"
     gene            complement(28031..29257)
                     /gene="murG"
                     /locus_tag="PC494_001714"
     CDS             complement(28031..29257)
                     /gene="murG"
                     /locus_tag="PC494_001714"
                     /EC_number="2.4.1.227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyldiphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase"
                     /protein_id="HDF3912216.1"
                     /translation="MKVLLSGGGTGGHVYPAIAIANKIRDEHPDAEIIFVGTEKGIES
                     EIVPKYGFELKTVTVQGFKRKIDFDNVKRVFKLFKGLEQSRKIVKKFKPDIVIGTGGY
                     VSGPVLFNASMGKIPAIIHEQNSFPGVTNKILSKTVTKVLTSFEDSHKRFPEAAEDKL
                     VFTGNPVRKEILLSRKNIARKNLSISDEKRMVLCYGGSGGSRKINDAMRLVIKNMVNE
                     DIAFIFATGKSYYDEFMGSISDINLKPYQKVVPYLEDMANALAASDLVIGSAGAISLA
                     EITALGKPSIIIPKAYTAENHQEYNAKSIEKQGAGIAILEKNLTPESLNTAVFKLLGD
                     RELLVDMANASKTIGKPEAIDLIYDEIMKVYNSTQKSASKKTKKEKVIKEVKEIKKET
                     TPSIEGQAKVIGIKKR"
     gene            complement(29275..30405)
                     /gene="spoVE"
                     /locus_tag="PC494_001715"
     CDS             complement(29275..30405)
                     /gene="spoVE"
                     /locus_tag="PC494_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein E"
                     /protein_id="HDF3912217.1"
                     /translation="MPKENLKKQIDIRMKTEFDGVVFYTTMLLVFVGIVMVFSASFIQ
                     SSFKHNDAYYFLKKNVIYAVLGFIVMIITSRIDYSFWKKNATAIGAIAVVLLLLVLTP
                     LGIEANGAKRWLGIGALTFQPAEIAKFATIILTAKLIEKNYDKIKSLTKGVVPLLVVP
                     GIFFALIILQPNLSTAGTVILVTFVMIFVAGMDMKIVFAMIGSGAALFAALVIAEPYR
                     LSRVTSFLDPFQDPLGKGYQVIQGLYALGSGGLFGLGLGKSKQKYFYIPEPQNDFIFA
                     IIGEELGLIGCIIVIMLFVVLVYRCVRIALKTSNVFACMVVIGIGAQIGIQAALNIAV
                     ATSSMPATGVALPFISYGGTSLTIFMGAVGIVLNISKHVKIN"
     gene            complement(30457..31812)
                     /locus_tag="PC494_001716"
     CDS             complement(30457..31812)
                     /locus_tag="PC494_001716"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HDF3912218.1"
                     /translation="MDLKGKKVLLVGLAKTGISTIKHLDKLGASIIVNDIKDENKLRN
                     ILDELKSINDIKYILGHHPEDVDDIDMVVVSPGVPLDLPFILKLKNSGKYIIGEVELA
                     FKLSNNPIFIGITGTNGKTTTTSLVGEIFSRAKRDTYVVGNIGNPVIDTIETSSEESV
                     LVTELSSFQLESIDEFRPKVSAILNITEDHLNRHHTMEKYIEAKANIFMNQTVEDFCV
                     LNYDDEIVKSLADKCNAKVIYFSRTKKVNGGVYLENNDIIIDIDDKIKFLNKDDVSLP
                     GGHNLENCMAAIAIAYVCKIDLEVIKDVLMTFKGVEHRQEFVRNLDNVIYVNDSKGTN
                     PDSTIKAIQSYDRPIILIAGGMDKGSNFDELLETAKSYVKSLVLLGETASNIENCAKN
                     KGFNDIHIVKDMEEAVKTSYEISKSGDIVLLSPACASWDMYESFEVRGKDFKDNVNNL
                     K"
     gene            complement(31831..32799)
                     /locus_tag="PC494_001717"
     CDS             complement(31831..32799)
                     /locus_tag="PC494_001717"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HDF3912219.1"
                     /translation="MMLGITELTYTALIAFLIVIIIGPIFIPMLRKFKFGQTVRDDGP
                     QTHLAKNGTPTMGGIIMIVAILITGLTRVKVSHDMAVGLICIAGFGFIGFLDDFIKIK
                     LKRSLGLKAYQKIILQVALSFYVAFYQYTSSSSASQLMIPFTDFVINVGILYIPIMMF
                     IIVAIVNAVNLTDGLDGLASGVTLIVSVFFMLFASSIAGNTEVAVLAAATVGACLGFL
                     GFNSYPARVFMGDTGSMALGGAVVAFSVLTNSVLIIPIIGGIYFAEALSVLIQVGYFK
                     ATRKRFFKMAPIHHHFEQCGWPETRVVFIFWIITVVLAWISIIAVF"
     gene            complement(32840..34213)
                     /locus_tag="PC494_001718"
     CDS             complement(32840..34213)
                     /locus_tag="PC494_001718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HDF3912220.1"
                     /translation="MECLTIKELVLATNGKLIYGDYNDCVSDIVIDSREANAQNAFVA
                     IVGENLDGHTFMKSAYDSGCKTFIKNESNGIKLESSDINLIEVKDTSLALGDISKYYK
                     EKFDIPFIGVTGSVGKTTTRDMIYSAISAKLNILKNEKNLNNHFGVPLTLFNLNKEHE
                     CAVIEMGMSGFNEIKYLVDIVNPKIAVISNIGLSHVEKLGSQEGILKAKMEITSNFDE
                     TNTLIVNGDDKFLSTLKEKEHVYKLKTFGFNKNNDVYCESYTMEEDSLTFICVINGKK
                     EEIFIPTIGEHNIYNAMSAILVGLCLNISLDYIKKGLKNFKGTKMRLDIIKNEKLTII
                     NDSYNASPDSMDAALKILGRYKGRRVAILGDILEMGEISEYGHRLVGKSSMNNTDIII
                     TIGENSVFIGEEAKQLGFNSANIYHFENREDVFNKLNELVKTGDTILVKGSRGMRLEK
                     IVEYLNK"
     gene            complement(34380..36359)
                     /locus_tag="PC494_001719"
     CDS             complement(34380..36359)
                     /locus_tag="PC494_001719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein D"
                     /protein_id="HDF3912221.1"
                     /translation="MRKVKRISKKRLVLVLILACALFFCLVIRTGYLQLMKGNWLSTK
                     ALEQQTRDIPIEPKRGTIYDRNMKELAVSVTKYTVWCKPVEVEDKKEAAEKVAEILDE
                     DYKDIYALISKKNMALVKVKRWIDDDKASQIRDAKLSGIWVAEDNQRYYPYGNFAPYV
                     LGHTSSDATGISGVEMQYDKKLKGKPGKLIVSTDASGREIPQGMEKYYEPVQGNGLVL
                     SIDEVIQHYTEKAVQKAYELNNAKKVTAIAMNPKTGDILALASKPDYDPNDSRTPIYP
                     YYQEELEKYNDKDKIKGYYQMWRNPAVSDTYEPGSTFKLITSSSALEEGVIKDGEKFT
                     CTGSVTVGGRKIKCWRHYRPHGTQEFKQAVQNSCNPVFVELGSRLGVGKMYDYIESFG
                     LMDKTGIDLPGEAKGILYNEKNVGPVELATISFGQSISVTPIQLITAISSIANGGDLM
                     QPRVVKSYTDNKGNITETVKPKKVRSVISKETSKKMLEIAESVVTEGGGKIAYIPGYR
                     LGGKTGTAQKVIDGKYAPGKYICSFVGIAPCDDPQIVVLAIVDEPTGVSAFGSTTAGP
                     IVKEIMNDSLKYLGVKPVYKEEEKAEYEKKQVKVPDVRNLKIGDAVKALEDAKLKPDL
                     DADIELPEDTKVKDIFPKPGVKVNEDSSITLYFEN"
     gene            complement(36371..36718)
                     /locus_tag="PC494_001720"
     CDS             complement(36371..36718)
                     /locus_tag="PC494_001720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3912222.1"
                     /translation="MKKNYKIHNLNEYKNKKKNNYKKRNKKKIGAKCILLIATFSVII
                     LNLCGYSKISEMKYDIYYLQKDLRKKEIVLEELKAKETEKTSIKEIELKAKELLNMDY
                     PKDGQIKYIDVDN"
     gene            complement(37199..38134)
                     /gene="rsmH"
                     /locus_tag="PC494_001721"
     CDS             complement(37199..38134)
                     /gene="rsmH"
                     /locus_tag="PC494_001721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HDF3912223.1"
                     /translation="MEFHHVSVLLNECIENLNIKPDGVYVDCTMGGAGHSKEIVKKLS
                     DKGLFIGFDQDKNAISTAKERLSEYESRVKFVHSNFENIKEELEKIGVYKIDGVLADL
                     GVSSHQLDEADRGFSYMQDAPLDMRMDVRCEFSAYDVVNTYTEDELTKIIKDYGEDNW
                     AKRIAKFIVEERANKPIETTGELVDVIKKAIPKKARIDGPHPAKRTFQAIRIEVNNEL
                     GVITKMINDASSIMNEGGRICIITFHSLEDRIVKNAFKHLASDCICPQHLPICQCDKE
                     SEVKIITRKPILPSEEEIEVNPRSRSAKLRVAEKI"
     gene            complement(38164..38910)
                     /locus_tag="PC494_001722"
     CDS             complement(38164..38910)
                     /locus_tag="PC494_001722"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HDF3912224.1"
                     /translation="MDRVAFTLFGIDIMWYGILMACGMILGTLIAIKEAKRVGIKEDD
                     VLNIAIIAIPVGLICARIYYVVFNWSYYAQNMSQIFNFRGGGLAIHGGLIGGILAGYI
                     YTKIKNINFLKMADTVILGMPLAQAIGRWGNFINGEAHGGATNLPWGIMVDGVKVHPT
                     FLYESIWDFGIFIVLLLFRKNKKYEGQVIVTYITLYSIGRFFIEGLRTDSLMLGPLRM
                     AQVISLIGVIGGIIAHVYLSKKNKNNISEE"
     gene            complement(39304..40590)
                     /locus_tag="PC494_001723"
     CDS             complement(39304..40590)
                     /locus_tag="PC494_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HDF3912225.1"
                     /translation="MEKIVNDILKEEVYYEKLQNGLDVYFMPKRGFMKKYAILATNYG
                     SNDLEFVPIGEDKKIRVNEGIAHFLEHKMFEQPDGGDAFDKFSKLGVNANAFTNFTMT
                     AYLFSATENFYESLEHLIDYVQTPYFTDENVEKEKGIIAQEIKMYNDDPDWNVYFNCL
                     KAMYVNYPARIDIAGTVDSIYKITKEELYKCYNTFYNPGNMALFVVGDLDVEKVIDVT
                     KKSNNYKVDRLSKSIERFYPEEPESVKEKEVIEKFPISMPMFNIGFKDSNVGLKGKEL
                     LRKEIVTDILVGMLFKKGSKLYEDLYMQGLINENFGAGFSSQVDYAFSIIAGDSKEPK
                     KVKEIILDYIEKSKKEGLSKEEFERTKKKKIGSFIKCFDSINFIGNSFISYVFKDINL
                     LDYLDVIKDITFEEVEERLKEHFKEEYCVISIVEPK"
     gene            complement(40605..41870)
                     /locus_tag="PC494_001724"
     CDS             complement(40605..41870)
                     /locus_tag="PC494_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HDF3912226.1"
                     /translation="MVNTKKIINLGNNINLTLIKTEKFKSNLISLYVQRLLDEKETTK
                     NALIPSIIASGSAKYPSARAISNKLDDLYGSSMGADAVKRGERQVLSFKVINISEKYL
                     DESIFEEVVEFFNEVINNTLVVDGGFKEEYLNIEKENLREKIQSIINDKKEYAQDKCI
                     EAMCKGERYSVSEFGYEDEIDSITSRELYEHYKNILKTSPIDIVVEGNFDEDKVVDII
                     SKNLKFEREEIINIPRADFIKNVDEVKVIDEQMEITQGKLVMGYRANVDYADIDKYYA
                     LVVGSNVLGGGPHSKLFVNVREKESLCYYIFSSIEKYKSIMFISSGIETKDYDKAVEL
                     IKKQVESVKAGDISDEELENSKLALVNSMKSITDNIGGMSDFVFSQSMAKTNSEVQDI
                     ISSIEKVTKKDIVEAIKNIELDTVYFLRN"
     gene            42186..43283
                     /gene="ychF"
                     /locus_tag="PC494_001725"
     CDS             42186..43283
                     /gene="ychF"
                     /locus_tag="PC494_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HDF3912227.1"
                     /translation="MKLGIVGLPNVGKSTLFNAITQAGAESANYPFCTIDPNVGVVSV
                     PDERLNKLQELYNSEKIVPTAIEFCDIAGLVRGASKGEGLGNKFLSHIREVDAIVHVV
                     RCFEDENVVHVDGSVDPLRDIETINLELIFSDIEILERRINKTQKAAKADKTLGSELD
                     LLKSIMSTLEESKCVRTMEFTEDEQTFVNSLDLLTSKPVIYASNVSEDDLADNGENNK
                     YVQQVKAFAETEDAEVVVVCAQIEAEISELDSAEEKKEFLETLGLEQSGLDKLIKSSY
                     ALLGLISFLTAGPKEVRAWTIKVGSKAPQAGGKIHSDIERGFIRAETIAFNDLVEHGT
                     MAAAKEKGLVKLEGKEYIVKDGDVILFRFNV"
BASE COUNT        13508 a         7966 c         4550 g        17304 t
ORIGIN      
        1 ctcaacaata aatacagttt tcataataat gaaaggtatt acttagcaat ctcatgattt
       61 tctaaataat acctttctaa aaattatttt tttaatttta tgaatttaat tatacttttt
      121 ctagtatcag gatttacaat taatatagaa ccaatcataa ttggtgttag tatacaaaat
      181 aaaaaaataa tatctttttt tagattatat tctttagatt ctaatttata attattattt
      241 attattccat cataatcact tatatttgac ttatttttat ttgtatcttg atttttgtta
      301 gaaatacttt ccctataagg aaaagaatgt tcattggtac caaatactga ttttgagctt
      361 aaatcataat tatcatcatt ttctgtaatt gaatttttat tgtaaaatcc tttttcttta
      421 tcagaattat tttctttatt accgtcttta ggtatatcat gaggattttt attttcattg
      481 ctatcagtac ttgattctac atcatcttta ggagtatttg gttgtttctc atcagaatca
      541 tcattttcat tattattatt ttcattatta ttgttttgat tgttattact atcattattt
      601 tcatttccat tattcccatc ttgattgtta tcatcctcat ctctatccgg gtcgtctcta
      661 cctcctcctc cacggtcacc atcaatatca tcattttccc gttcatcatc tggcgtctct
      721 tggttgtctc cgcctcccat tataaatcct ggtttaaaaa ctatatttga atacccttct
      781 tttaatcctc ctacaacttt tactctaaaa caacgcaact taaaatcttc aaaaaaaagt
      841 atagcttgat ctctaatatc ctcctgctct tcagatatcc aattgattcc atcgcttgaa
      901 tattcaacaa aaaccttact tgcactatac ggcatatcat aaaataaaac agctacatat
      961 ccattttttg tattttgaaa ttccagttcc aaattgtcta ttggtttttt ctctataaca
     1021 gatacattca aactaggaac tacatcatca tttattataa ttttttcttt atttaacatt
     1081 tctgttttaa actttcctgt tatattaaaa tcttctccct tttccaactt ttcataataa
     1141 tcagtaaaat cccattctac atctatatca agtcgattac cactagatgt ttctaatacc
     1201 atatatttgg gaaattttat attttctatt ttatcatctt tacttacttt tatttcatca
     1261 ctaaatacat caattcccct atgacaacat ttcacaatat catagccaga atcttcagct
     1321 atagagggta taagctcatt ataatcatca attatataaa ctttcttact ttctgatata
     1381 attgattgtg ccaacttatt attatctttt agtaacccac tttcattgtt gctactatat
     1441 gcttttattg aagtttcttc tatctcaaca tcacctttag aataaacacc tatagcatgt
     1501 tctccattca cttcaatatt cttatttagt attctaatat cattttcagt ataaattcct
     1561 attgcatctt ttccatttgc ctttattttt tcaacagatt cgtaggatga tttaatatgt
     1621 aagtctcctc cttcttcaac gtataaggct gtcccatcag tagcaattat gttgtttata
     1681 ccaatactta tacttccacc attttctata tgtattactc cttcttttcc tccttcacct
     1741 gttatattca attcattatc atcaataata aatctcccat gattttttat caatatttta
     1801 tatttgttgg tatctattgt aaaattactg tcataaggaa tataaaatct aaactcttca
     1861 tctattacca tatcacaaga aagagtataa actatttctt ctttattatt tttattttct
     1921 tgaacccacc tttcaaaatc ttcaagacaa ttttcctctt gtccaaaaac tttatgtgga
     1981 aaacttataa aacacaaaac tattatactc ataaaaataa atatctcata ctttttcatc
     2041 ttacactcct agaaattttt agctttgaaa caatcctgtc gaaacatata cttcacccac
     2101 tataattttt ccacaattat caattattgt caatttatat aagtatgttt attaattgtt
     2161 ataaataaaa agctacttac taaagcaaac agacgtttca ctttaataag tagctatatt
     2221 tttataacaa aatagttata atattagaac ttccttcatt tacaattttt tgtaaagtct
     2281 tttgcatttt aactcttatc tcttctggca tagtatataa tttactttgt aattgctctt
     2341 ttactaagtc atgtagtgac ttaccaaaca tatttgattc ccataaatct gctggttgct
     2401 cttcaaatac ttccataaga tattttatca tctcttcacc ttgattttga tttccaacta
     2461 ttggagaaac ctctgtagat atatctgctt ttataatatg aagtgatggt gcattggctt
     2521 ttaacttgat accatattgt tttccttgtt tcattatttc tggttcttcc agactaagtt
     2581 cttctaagga aggagctact actccatatc cttttatctt ggcatctatt aaagcacttt
     2641 ctattttatc atactcattt ttaactttag atagtctagt tatcagacta agcagttgat
     2701 aatctccttc aattttaaat ccactttttt cttcaaggac attatagaat aaatcttgct
     2761 ttgtctgtaa atcaatattt ataacacctt ctcctagctc tacattatca acacctgtat
     2821 cttccaaaaa ctctagctca gaaaatcctt gtataatacc ttctatatcc cttattttac
     2881 ctatatctat aatactttgt tttaatgttg ttattatgct actttttatc caatgatttc
     2941 tttcaagacc ttcaacccat tttggtaagt tgattcttat ttctgtaagt ggaaaatcat
     3001 ataatacagc ttccataacc tcctctatat cttcttcttc catttcaacc acattcattg
     3061 gaagaactgg aacttcatac ttttcttcca attcacttct aagcatactc gtttcctcac
     3121 tttttggact taacgtattt aaaaccactg caaatggttt tttaagattt ttcaattctt
     3181 gtataactct ctcttctggt tctacatagc tttttctgtc aattccagta actgaaccat
     3241 ctgtcaagac aactatccct attgtagaat ggtcttttat aactttttta gttcctatct
     3301 ctgctgcctt ttcaaatgtc atagcttctt gtgaccaagg agtggatact aatctttgtt
     3361 ttccaccttc ctcatgccct aaagctcctt caactatgta tccaacacaa tctaccattc
     3421 ttacttttaa agatactgtg tcttttattt ttatttctac accatctgct ggtacaaatt
     3481 ttggttctac tgtcattatc gttttacctg aaccactttg gggtatctca tctcttgttc
     3541 tatccttttt aaattcattg tctatattag gtataaccaa cttttccata aattttctta
     3601 taaaagttga ttttcctgtt cttacaggtc caactactcc aatatatata tccccctgag
     3661 tccttttgga tatatcttcg tatatgttat tattcatatt attcctccta tacatctaat
     3721 cttattaaat tatatttaga gttaagggtt aatattctta aaatagaaaa ataaagacca
     3781 gcaatattaa tttaatttac atatagaaat ttgtaaattt caatgtaaat taaattaata
     3841 ttgctggtcc aaatagtagt gtattatatt aactgacttt agtagtattt tcatttgaat
     3901 tattattcat ctcaataagt tctttacgtc tttcttttgt catgttcatc catataaatg
     3961 taaacaccaa tccaattatg gctactatag taagaactat gaagtagtac ctatatccag
     4021 ttacacccgg aaatgcatcc aatatcttcc ctgctgctaa aggacaaagt acttctggaa
     4081 gatatcctaa tgtagcaact attcctatag cagttcctga tattgataat gaataattac
     4141 cttcttcaag taacgaatag tgtaaacctt gaattgcata catagataca tatattgcaa
     4201 cacatccaat caatagtata taaatcatag atgattttgt tggtgtaaat attacaccta
     4261 aaagacctgc aatcataagt ataaatccat aagatataat ctttgatgaa ccaactttat
     4321 ctccaagtaa tccagaagca gctgatgcta ctggtctaca atactgagct aatattgaga
     4381 ttgcagatgc aaacaccaca gtagctccaa atgattcagt tgaataaggc gtaaaataat
     4441 aaaatgacat attagctgaa tatgaacaaa acattattat tgttattatc catgtatgag
     4501 gcatttttat tactgcaaaa aaggcttctt tatcaaattt tgctgatacc tctttttcat
     4561 tatcctttaa tttgaaaaat actaatactc caactattac atttattgcg agtataatac
     4621 tataatagct gtaagaccag atttatcact tacttttgat gaaatatacc caaatagtat
     4681 caatactaga gatagatgaa ttgcattggt aattccacga ccactttcca taaatccaaa
     4741 agcttttcct tgttcatttt cagatgctaa cattctaaca gcttttacaa gagctggcca
     4801 aaaagtaagt attgttgtta ttccccataa ggcatggatt aaaaacacaa caatatatgg
     4861 aggataaagt gttaatacaa gaccagatat tcctgtaata attaaagaac ctgaaagcaa
     4921 ttttctggct gaaatacggt ctgctaaaaa accaccaaaa aggtatgata ccattgcaag
     4981 tagaccataa atacttccta agcttcccat ttgtgtattt gtaagattaa atgcttgtgc
     5041 aaaagtatca taataataat tctttaaata tggtaaagca tatataaatg ctcctgctac
     5101 aaagagtatt atcaagactt tgaaattttt ccaaatgctt ggtttattta cttcaactga
     5161 catacttcct ccttatgtaa atacctgtaa attttcataa taattaatta ttgcttattt
     5221 tattgtttat tcaatattta ggaatattta ttaatatatt aggttaatct atcaataatt
     5281 tatggtgagt tatgagctaa aagtaaactc ttttagctca ccataataat tatattttta
     5341 tttatactaa catccagagt tattagatat ctttttttca tagttcttcc atagcattaa
     5401 acctgttatt ataacaaaaa gacctcctcc tatcatttca atctcataga ttatattatc
     5461 ttttaaagtc tccataactg gtgccgttga gaaaagtatg ccaactacag ttactacaag
     5521 taccattctg gcaatattga tacaaactga atcacttttt gcaattgaat atggtctttc
     5581 ttcatttggt cttgtctttc taagtctaat ataagatgta aaaagcaaga catatggaaa
     5641 taatgctgtt aatgctgtca tagtaacaag aacattgtat atattatcta ctgatggtaa
     5701 taagtttgtt cctacaagaa gtagactcac tattatagcc tgaactatta ctgcatttga
     5761 tggtatattg tatttatttg taacagtcaa ttgcttagga aatacacctt ctcttacatt
     5821 tccaaaaagc atctttactg gacctgctat ataaagtatt aatgctccta gtactgataa
     5881 agttattcca aatgctacta ttcttataaa ccaacttcct atacctaaat cttgtgcaac
     5941 tttagctaat gcatctagta tccctgtaga tgctgcaatt ttatctggag gaagtatcat
     6001 tgttattgct actgaaccta agatatagat tcctcctatt aaaacagcca cagttaatat
     6061 agctttagga aagtttttct tagcattatc catttcggtt atgaaattag cagtcgtttc
     6121 agctcctgat aatgcaaata ttatagcaga tatagaaact aatgaattgg catctatttt
     6181 tggtattata ttttggattg tatatatcga tgctgatgga gcttttttga gaataactac
     6241 agacataaat gccatcacta taagtaatat agcaggaatt gtagaaccta atgctcctgt
     6301 attcgtaaaa aattttccaa atgccatccc acgagtactt actaaggaca acagccaaaa
     6361 tattatgagt gaaagtgcta aaataaacat cttattgttt gataaatctg gatttccaag
     6421 catatatgca atatttatcg ctaaaaaagt caagaaagaa gaataccaaa atatctttga
     6481 tgtccaattt agccatgaca ccataaatcc ccacttctct ccataagctt gtttaaccca
     6541 ttctccaagt ccaccatctt ttggatatgt tgcagccaac tctgcacata taagtgatgc
     6601 aggaacaaag aatataaaag caaacaataa ccaaactggt atagaaccaa gacccaatcc
     6661 aaaactagag gcagtagatt tagctatcca tctaatccca aatagtgctg atatattcat
     6721 aaatactaaa tcccaaaatc caattttctt tttcactgta attcctccaa tttcaaattt
     6781 attcagactc atacacaatg tattgactta aatatcaagt ataagttctt caacacttct
     6841 tggataatta gttataattg tagcaccatt cttacctact attgctgtat ctgagtgtct
     6901 aaatcctcca actccaggta tatatatccc tggctccata gaaaatacca ttccttcttc
     6961 taatattaat tcattgtcaa atcttaaata tggctcttca tgttctgata aacctaaacc
     7021 atgaccaatt ctatgatttg aatataactc tagaccatac tttgcaacaa cagctcttgc
     7081 tgcttcatcc accattcttg ctggtatacc agcttttatt gtatctaatc cagcttgttg
     7141 agcctctact gcaatcttaa acacttcttt ttgtctttct gttggtttgc ctataataaa
     7201 agttctttca ttttctgctc tatagttttc ataccaaacc tgtctactat gtattactat
     7261 atctcctctt tgaagtattc tagtattgga atctaaatga ggttgtgctg ttctatcaat
     7321 ccctgaacaa gtccagtttg caaatcctat atatgtatca ggataatttt cagaaacata
     7381 ttttagtaaa gcattatccc ctgcaacgtc aaactccaat tcactcatcc caactctaac
     7441 attttctaaa gaccctttta ttcctatatc agataggtaa cctgctatct tcaaaaattc
     7501 tatttctttt gcatctttta catatctcat ttcaaatatt ttacttccaa catctttgat
     7561 agcaaatgac ttatcagtta tatactctga aaagcttgca gatactatat ctttttctat
     7621 tccaacagtt gttcctttag ggtatttatt taaaattata tctaagtaat gtttatgtga
     7681 tattccatgt tctttcattt ctggtatttc ataatacaca tatacattat caacttttgc
     7741 aacttcttta gcatgtaatt cttctaatcc aggtactatt aattctattt tatcttgagt
     7801 tactactgtt acaattggtc tagaataagt tattgcttta aatccactaa tataaaattg
     7861 attgtctggt tcaaatatta aagcaatttc aatgcttttt tcattcatgt actttctcaa
     7921 tctttctagt ctcatattat ttgacataat gcacctcttt cttaatattc agataattta
     7981 ttcaatacaa caaggatgaa tatattattt taaaattctt aatattttta gtacttgtcg
     8041 tatttgtatg taaattaatt ttatttgtga ttattttatc ataatcatga ttattttgtc
     8101 aatcatgatt ttattttaaa aaatttttta tattctagtg attttaaatt atctaaaata
     8161 taacgagtat acattgtatt ttgtaatatt attcttgatt tatggtaagt ttaatgataa
     8221 aatcacgatt atataaacta tattgattat ttgtaggtga ataaaatgac aaataaagaa
     8281 ttacaaaaga aaaggatatt gatgtatttc atagaagctg ctcaaaatat tatggaaaac
     8341 gaaggtatag aaaatattac acttcgtaag gttgcagata tggctggcta taatagttca
     8401 actctatata aatactttaa aaatttagac catttaatat catttgcatc tataaaatat
     8461 tttaaagatt ataacttgaa tatttcaaga tgtatagaaa atgtcaatga tgaatataag
     8521 aaatatataa ttatgtggaa attattttgt aagcattctt ttgataatgc tcaagctttt
     8581 taccaggtat tttttaactt gtctagtgat gaacttagct atataacaaa acaatattat
     8641 gatatgtttc cagaagattt aggtattcat gatagtgaca tatctttaat gattacagga
     8701 gaaagtataa aggaaagaaa taagatacta ttaaacaatc ttgtagatac tggatatata
     8761 ccagctaaag atttagacat aatcaatgat ataattattt ctttttatca aaatctatta
     8821 ttcttaaaaa agaacacagg aaaaaattct gatgatgatg aattaactat gaaaatgatt
     8881 tcttctattg aatacataat aaaacatgct aaataaaatt aaaatatggc tgtctcaaaa
     8941 tagagataag ccttttttat tgttgaaata ataaaaatat atttaatttc atataaaaaa
     9001 gagtgcctcg taaactaaaa agttcatttt gagacacccc taaaataaat ttattattta
     9061 ttatacaata gtttatatat catcacctaa aactacttct tccatttcat gctttttact
     9121 tctcatcatt agttctattc caacttcttt aggatttgaa cctttcttta ttacagaata
     9181 tatagcatta gttataggca tatctatatc taatttttca gcaacatcat gtgctacttc
     9241 agtagcagtt atgccttcta caaccatctt tacttctttt aaagtatctt ctaaactcat
     9301 ccctttacct atgagtatac cagctcttct atttctacta tgcatacttg tacaagtaac
     9361 tattaaatct ccaatacctg aaagacctgc aaaggtagac atattagctc ccatagcaat
     9421 tccaagtctg ctcatttcac taatacctct tgtcataagg gcagcttttg cattatcacc
     9481 ataccctaat ccgtcacata tcccagctcc aaatgctata atatttttta atgctcctcc
     9541 aagttctact ccaactatgt ctggattcgt ataaactcta agtttagggc tcataaataa
     9601 atcttgtatc atctgtgcta tttttaaatc tttagaagca actactacgg tagtaggaat
     9661 atcccttgct acttcttcag catgagatgg cccagatagt attacatatg gattttgtgg
     9721 taattcttct tcacagactt gagataatct aagcccagtc cctttttcaa gacctttagc
     9781 tacattaaca ataacttgtc cttcttttat aaatggtttt attttttggc aagtacttct
     9841 tacagcctgt gatggaactg ctaaaactat taccttacaa tcttttatag ttttttctat
     9901 atcagtactt atagttatat tatttggaaa taatactcct ggtaaatagt ctgtattttc
     9961 tttagttctg tttatttttt tagcttgttc ctcttttcga gtccacatgc tcacatcatt
    10021 accttttttt gcaagcccta aagctaatgc acttccccag cttccagtac ctaatacaca
    10081 tactttctcc atgtttaaca ccacctgagt ataatatatt tactattctt tcttttgacc
    10141 aatttttctc tctgtcccat ttaataatcg ctttatattt gctctgtgat tatatattac
    10201 tgatgcagtt aagaacagag ctactattaa accagcttta ttttttacca taatcataaa
    10261 tattggtgaa catcctattc ctacaacaga acccaatgaa acatactttg ttatagctac
    10321 caccaatata aatactgcta gacacattag tgttattact ggatttacag ctagcattgc
    10381 ccctagtgaa gttgcaacac ctttgcctcc tctaaatcct aaaaccgctg gccaattatg
    10441 acctgctaca acacatataa ctgccagata tccagctaaa agagtatcta ttccaaccaa
    10501 tcttgctgca aattctgata ttaaaacagc cattacacct ttaagaacat cacctaaaaa
    10561 tgtcattgct cctgctcttt ttccaagtgt cctaagtaca tttgtcgaac ctgcattacc
    10621 agaaccttga gtccttatat caaccccagc aattcgcttt gcaactatgt atgaggtaga
    10681 tatatttcct aaaagatatg caactacagc aataattata taactaaata tctccactga
    10741 atttcccccc tttagttata ttttaagata tttatttttt atttttttgt ctatactcaa
    10801 actttatgga agttccttca aatccaaaat tttctcttat cttattctca aggtatcttt
    10861 gatatgagaa gtgagttaaa tccttatcat ttataaacaa tgtaatttta ggaggtctaa
    10921 tgtcagtttg agtcccatag taaattttta atcttctacc tttgtcagat ggtggttgat
    10981 ttaacattac agcttctcca attacttcat tcagtgctga agttgatatt ctcttagaat
    11041 gttcatttga cacatattca actgtatcta gtatcttgtt cattctttga ttagtttttg
    11101 cagaaacaaa tacgattgga gcatacatca taaatggaaa tttttctttt atatcttttg
    11161 tgtaattgct catagtctta ttatctttct ctattaaatc ccatttattg attacaaata
    11221 tgcatccttt tccttcatca tgtgctatac ctgcaacctt tgtatcttgt tctgttacac
    11281 cttctaaggc atctattact atcaatacta catctgctct atctacagca ctcatagccc
    11341 ttattacact gtatttttct attgtctcat atattttact ttttcttcta agccctgctg
    11401 tatctattag aagaaatttc tgtccatttt tttcaaaata agtatcaatt gcgtctctag
    11461 tagttcctgc aattggactt acaattactc tttcttctcc aagtatctta ttgagtatag
    11521 aactttttcc tgcatttggt ttacctgtta tagctactct tattatatct tcttcatact
    11581 ctgtatctaa tcctgctgga aaattttcaa ctatctcatc taataaatct ccaaatccca
    11641 tactattggc tcctgaaact gcaaaaggcg ttccaaatcc caactcataa aaatcgtata
    11701 tattatcaaa ttgactttga ctatcaatct tattaaccac taagattact ggtttttttg
    11761 tctttctaag caattgtgca atttctttat cagcagctgt tattccagct ttaccatcaa
    11821 ctataaaaag tattacatgt gacatgtcca ttgcaagcat ggcttgattt ctcatttgag
    11881 ataatattat atcttcgcta tcaggttcaa ttcctcctgt atccactaat gtaaaatatt
    11941 tatctaacca ttctacttca gcaaatattc tatctcttgt aactccaggt gtattttcaa
    12001 ctattgatat cctttttcct gcaaatttat taaatattgt agacttacca acgtttggtc
    12061 tcccaactac agctacaact ggcctactta tactcatttt atttctcctt ccatcttttg
    12121 ttttctattt taaaatttta tccacaaaat cttttccttc attcaaacaa gggataattt
    12181 ttattctcat aagttcttct aattgattta attcaatatt atctaagaaa atttcttcat
    12241 ctgcttttag catacttctt gttatataaa gagcttctcc taattcttta tcttcaagtt
    12301 gttcttttaa atccttagct gttaaaagac ctgatacagt tattgtctct ccaaaaaact
    12361 tgtttttgat ttcatataca tttacttgaa gatttttaaa cttgtccatc atagcatctg
    12421 ccatactctg tataaattca tatgcagaat gaccagtagc tattgatact ttcttctctc
    12481 tttttagaat cttctcaggc aatatattta gatactcttc aatctctgtt tttaacttac
    12541 gtatcatacc tacaccatct tcaaactgta aaaaaccttc atattcttca tatccaggca
    12601 attcactatt agatagtata taaaattcat ctgataaaaa tgcaaatcga gtacctaatt
    12661 tttcaagata tttctgttgt atttgatgta tttgctctat agttttactt gcgctcttat
    12721 cattaaatat atttaattct actagatttt ctctatgctt tgtaatccca actggaacta
    12781 tcgcaacact gtttacatac ggataaagtt gagctagttc ttttattgtt ctatccaatt
    12841 cctttccatc atttatacct ggacataaaa caatttgaca gttcatttct atatgagcat
    12901 ctgccaatct cttcattata ccatataatt ttcctgcaaa tttattgctt atcatttttt
    12961 gtcttaactc tggattagtt gtatgcacag atatatttat aggacttatt ctatatttta
    13021 taatattatt tatatcttct tcactcatat ttgtaagtgt gacaaaattt ccttgtaaaa
    13081 aagataatct cgaatcatca tctttaaaat aaagagtttc tctcatacct tctggcaatt
    13141 ggtctataaa acaaaacata cacttatttc tacagctttt agcttggtca attatcggat
    13201 ttgtaaattc aacacccaaa tcttcatcat agtctttttc tatctcgtat atgtagactt
    13261 cgccatcttt tttttgtatt tctacatcta aatattcatc acttagtaag aatctatact
    13321 ctattatatc atgtattggc tgttcattca cagatataag taaatctcct acctctatac
    13381 ccatttcttc tgcaatacta tctttataaa ccttacttat aatattattt acttttttta
    13441 catttacttc caatattttc accactcttt tgtattcatc aatgcttatt ataatgtatt
    13501 ttaatatgca atttatttat ttattatatt ttatgatagc atttttaagc atttcatgtc
    13561 ataataacac attttaattc taatagtcaa tataagtaaa tagctataaa atagattaga
    13621 acaaataata ttcaaattta agtttcttaa aaatttaaat attatttgtt cttaaaaaaa
    13681 ttttataaat ttaatgtttt actatgatta acgtcccatt tgtcatatca tgaaccattc
    13741 cacctacaca ctttgacatc aacaatgcct tattttgtaa gtctttctca tcatttgcat
    13801 aaaatattgg acaacctcca ccatttttca tattcttatc aagtgtaact atagctaggg
    13861 tatattcatt taaacctata tccattccca tctcatgcac ttcctttctt tcctatttta
    13921 taatttttta gtgataagtt ttttccttta gagcttgaaa gtattgggca tgactttaca
    13981 gcttccatta ctttttccac attcttatct actggtaaat aagcaatcat tatactttca
    14041 tcctctttat ttcttctagg taatggtacg aatgaaggtt ctccataatc tccatataaa
    14101 cctaaccttg aatatatatt gtatactatt gcttgtcttt gaccggagtc aaataatatt
    14161 cctgcattag cataatcctt atttttagga attatttgta ttcctacacc tctattaata
    14221 tatacttctc tatcgctttt tagacctata tttgttatac cttttaaatc tcccaccttt
    14281 agtatagatt cgtccacaaa actaatttca gcaggcatta catcagctat gtctccaata
    14341 ctttttctag taagaagttt ttttaatata aaggctaaca ctaatccaca aattgaactt
    14401 attaccaaac tcatcccttc acttattttc gtttctgcaa gtattacata atacaatcct
    14461 attgttaaaa aagatgtaac tatacacata taatttctta cttcataggt tctagctatc
    14521 tcttctatga atgcagctcc tctctttaca agttgaactt cctctaaatt ttgcaatgta
    14581 tttcttctat ttgctctcac ttgtctaaat tgttctgctg ctagagataa aaaagttata
    14641 gatgtataag aacgatttat aagagctgga accaataatg ctcctaatga agaagcgacg
    14701 aatgctaata taagttgaga tagtaaaaca tttggttgcg ttggatactg tttttggtct
    14761 aaattcaaca ttataattct agatgttata ccaataataa cagcaacaaa aaatactcta
    14821 tccattaaat cactcctaaa atatttaatt tgaaatttta catgtaaatc tacaaagtct
    14881 ttctagaaaa atcactctgc tttccttttg atgtttctat gataggtgta cttttcacta
    14941 catctatcat gacatctata tctttgagta ttggcatata tggtataacc acagtacttt
    15001 tttctaaatt ggtcttagat atagcaacaa tatcaacctc atctacatct ctatctatcc
    15061 ccatatgaat aaatagatta tgtattatag cttgtctttg ccctatatca tttactattc
    15121 caaatgcacc taaatctctt ggtataactt ctatggccag acattcattt ctatactttt
    15181 ctcttgtact ttctagacct atgttagtta ttattacacc atttaccatt aaaataggtc
    15241 cttcaaaact tatttttgca ggaactatat ctgctatatc tgctatactg ttccttctta
    15301 aaaatcttct aaaaatcaaa ccaacaatag ctcctgacac aatagctagg attgtgcaat
    15361 aaaaaaagct aaggccatac tttcttgcaa aaacgatata aactatcgaa gataccagtg
    15421 cagaaaaaag acttatataa cttctagatt catacgtaga tgctatttct tcaacgtaag
    15481 cgtctccttt tggtactaat tcttcattat cgatattctt tagtgttatt ctttcttgtt
    15541 ctgcaagacc ttgaaactgt tgtattgcta ctgcaaaaaa tgtcaaggct gcaaactcct
    15601 tatctataag tgcaggtaat gctatagcac ctaacgaagc tgaaagccca gatataatta
    15661 tctgttctaa ataatcttgt ggtcttgatg ggtattgttt gtctgtaact cttaaaacta
    15721 atcctctaca taatattcct acaactaatg caactataaa agagtgtcta aataaatttg
    15781 cattcaataa actttcttcc attttctcag ctccttctct tatatagttt gtgcaaaaaa
    15841 caaaaaaaat tcccttctat ttaaggaaat ttttttgtaa tattgtaact ataaattcgc
    15901 taccaatgcc aagttcactt tttactttta tacatccatt tagtgatttg actatatgct
    15961 ttgttatagc caatcctaaa cccgttcctc ctacatccct acttcttgct ttatctaccc
    16021 tataaaatcg ttcaaatatg cgttctacat cttcttttgg tatccctaca ccattgtcta
    16081 taactttaat tacgattttt tcttcatctt ttaacactac aacttgtaca atcccattat
    16141 cttgggtata ctttatagca ttatcaacta ggtttaagaa cacttgcttt atatagtctt
    16201 tattggatag tatacttatt gatttatcat cacatttata taaaacttct atattttttt
    16261 cactagctga atgttgagtt atttcatata cctctttaaa tacatcatat actacaacat
    16321 tttccataag aagagtatct ttattttcta caaatgataa cagcaatata tcatcaatca
    16381 acctttttaa tctatctgat tcgctttcta ttatttctaa gaatctattt ctagtattca
    16441 catctatatt ttcatttgac tttagtgttt caacaaaccc acttatagat gtaagtggtg
    16501 ttttaagttc atgacttaca tttgcaacaa aatcacttct catattttca agtttaactt
    16561 ttttagtaat atcttctata tttactatcg aacctattat tacgttgtta gtattctgaa
    16621 gataaactgg gtctactttt atcttatata cgatatcatc tttagtagta atattagcag
    16681 tttcattatc tttagaacca ataaattgaa gtatttgttt taatatttct tcttctttta
    16741 ttacaacatt aatattatga ccttcaacta attgatttgg ttcactcttt atcatttctt
    16801 ttgcttcatc atttatcaga agtatatttc catttacatc tatagctaaa attccatgag
    16861 atatactctt taatatagac cttaactgta aatgtttata ctgtacttct tctaaggttt
    16921 tatccatatt ctttatcata tgattaaaat ttctagctaa ttcgccaagt tctcctttgg
    16981 ctgatatgtt aagcctagca tgatattcat tattacttac tttttttgag acgtatataa
    17041 actcttttaa atattttctt aatgttattg tgtatcttac agctaatata acaatggcta
    17101 tggacaacat aacaataaaa aaatatatac tatttaaatc ttccacaaga taacactcct
    17161 aaaatataac ctttttaatc tattttgtat cctacacctc ttatagtctc tatatatttt
    17221 tccgatttat cttcatcttc tatttttttt cttaaatatc ttatatgaac atctactgtt
    17281 ctagtttctc catagtattc atacccccat attttatcca aaagataatt tcttgaaagt
    17341 acttttcctt tattttgaat taataatttt aacaattcaa attccttaag agttaactct
    17401 atcttttcag agcctttggt aacttcatgt tttgataaat ctagttttaa attacctgta
    17461 gtaagtatat tgttttcttc acctaagcta gtcaaattat atctccttaa aacagaacta
    17521 atcctagcta acaactcttt tatactaaat ggcttagtta tatagtcatc agcacctatt
    17581 tcaagccctt caaccttgtc attttccata tttttagcag taagcattat aacaggaata
    17641 ttttttaagt ccttatcact tcttattttt ctcaaaactt ctattccact tatatttggt
    17701 aacatccaat ctaaaagtat taaatctggt ttaatttcct tagcctttat aaatccgtca
    17761 aatccatcat atgaataact aacttcgtaa tttgacacct ccaaattgaa ttttaatagc
    17821 tcaactatat gcatttcatc gtctataaca agcactttag tattcattaa aaagctcctc
    17881 tctattttat ctgtagtacc gttcctattc gttctgatgc cttattatgt tttctataag
    17941 agtggaattt atctgctcta caactagtgc ataaatttaa atttattata ttttcttttt
    18001 taactccact acatctaagc atatactcat taattttcca taaatctaaa tagtaacttc
    18061 cctcttttat tatatagaac ttttcatcat tatttgtaag aattgtgtta aatttttcta
    18121 ctaaatcttc agacacttca taacaacatg gtccaattga tggtccaatt atacatacta
    18181 aatcttcagg aactgtttta tagcattcag acattaattt tattgtttta tgacctatat
    18241 tactaaaagt ccctctccaa cctgcatgag ccagtcctat ggctttattt ttagcatcta
    18301 taattgatat aggtacacag tctgctgtaa acagtaaaag tggtactttt tccaagtttg
    18361 ttataagtgc atctccatct cttcttttcc ctatagtatc tttattgact atagtaacta
    18421 tatctgaatg tatttgagaa ttactagtta gattttcaaa tgtcaaatca cattctttac
    18481 atacttttaa catatcttct ctattttttg catctatatt cttacatgtt ataactagat
    18541 ttacagaatt taatttttca tcaagttctt cacaattacc acttaaatta acatactctt
    18601 taatatcttg tacatttttt atatttatat aatctttcat catttgtctc ctttttctat
    18661 cagtatactt ttaagttcat ttacaaaagt atttatatct ttaaattgtc tatacacaga
    18721 agcaaatctt acataggcaa cctcatctaa ctctttcaat ttatccatta ccatctcacc
    18781 gatttttttg gtttcaattt cttctataaa acatttattt atttcatttt caatatgtac
    18841 aacaatactt tcaatctcgt caatagaaac aggtcttttt tcacatgctt ttagcaatcc
    18901 atattttatc ttttctctat caaaatattc tctactatta tcctttttaa tgaccattaa
    18961 aggagttgtt tctattttct catacgtagt aaacctcttt ttacatgatt cacactcacg
    19021 tcttcttctg atagatttta aatctgtatg tctagaatct attacctttg attctttata
    19081 attacaataa ggacattgca tctatactcc tcctttgttt aactatatct caaactcatc
    19141 taagcttaat tctgaaccta tatttactat tattgtatca caacctattt taagtatatc
    19201 attccaaaat ataacttctt catcccctcc tcttgaaaaa aaacttctac ttccatctcc
    19261 aaaaatggta aatgagacta ccttaccttc gtgaatatcc atgtctatgt ctattataaa
    19321 ccccatcctt tttccatttt ttacatttat aatttctttt tccattatat cagaaactct
    19381 aatcatattg tactcaccct ttctttaaaa ataaatatgt atcgaagtaa aaaaaaatga
    19441 cctatatagg tcatttaaat taaaataatg tttacagtcc atggattact tatacatatt
    19501 ttctcatatt ttttaaagca tttttttcaa ttcttgatac ttgtgcttga gatataccga
    19561 tttcatcagc aacttctatc tgagttcttc ctttgtaaaa ccttaaatct aataccaact
    19621 tttctctact atttaatttc ttaatagctt ctttaagtga tatttcttgc aaccaatttt
    19681 catcagtatc ttttttatct tgaacctgat ccataacgaa tattgcatct ccattgtctt
    19741 gatatactgg gtcaaacaga gatattgggt cttgtatggc atcaagtgcc attacaactg
    19801 attctacttc taattctaat tcctttgcta tttctgatac tgtaggttct ttagaatttg
    19861 ttctaattaa tctttctcta acttgtagtg ccttatatgc tatatctttt aatgacctac
    19921 ttactctaat tgggttattg tctcttagat accttctaat ttctcctata atcataggaa
    19981 cagcataagt tgaaaacctt acattttggc ttaaatcaaa gttatctata gcttttataa
    20041 gaccaataca acctatttga aataaatcgt ctatattttc tcctctgttg ttaaactttt
    20101 ttattacact caagactaat cttaaattcc ctcttacaaa ctgttgtctg gcttcttcat
    20161 caccattttt tatttgtaat aaaagttcct tcatttgctt atttttaaga actggaagtt
    20221 ctgatgtatt aacaccacat atttcaacct tattaacttg catatatttt cagtcctctc
    20281 tcaaaagtat tcatctattg aaattattta catttccaat ttttttatac tttttaagaa
    20341 gaattaattt agcattatac aaattttttc atttcttttt gcaaccttga gattattttc
    20401 ttttcaagtc tagatatgta ggactgtgat attccaagta ttccagcaac ttctttttgt
    20461 gttttttcaa tacctttatc aataagacca aatcttaatt ccataatttg cttttctctg
    20521 tcacttaatc tgtcaagtgc cataaccaac aaatctctat ctatttcttc ttcaattatt
    20581 ttgtatattt catcattttc tgtacccaat acatcagata ataaaagttc gtttccatct
    20641 aaatctatat ttaaaggttc atcaaatgat acttctgttt tctttttatt attttttctt
    20701 aagtacatta atatttcatt ttctatacat ctcgaagcat aagttgccaa ttttatattt
    20761 ttattcagtt taaaagtatt aactgctttt atcaaaccta tagttcctat tgaaatcaaa
    20821 tcttctacat ctatacctgt attttcaaat tttctcgata tgtagactac taatctaaga
    20881 tttctttcta ttaaaattga ctttacactt tcatctgttt ctagcttttg taaaagctcc
    20941 atttcttctt ctggtttcaa tggaggagga agtatatttg cccctcccat atagtatatt
    21001 ccctttggct ttattatttt taatttaata cctaacatag taataaagct tattattctt
    21061 tctttcaatc gtaacattcc ttgtccccct taaattttca cctaaaatcc aggcaatata
    21121 tttggattca ttattgctcc atattctcta tcattaaaat ttgaaatacc aagtattata
    21181 tttcctatct tttgctcatc tacttctata tagtcagctt ttaagcctat tattatgctt
    21241 gtcttattac ttccagcatg tttataaggt attattctaa ctctacctga agttttatca
    21301 tctaaacttc ctataatttc ttgtgctttc ttcatatcta tatcttcata attaatattt
    21361 aatagttttt ctggaataaa tccttctaac acactagact taactattat tacatcactt
    21421 tgacttattg ggtcttttaa caaattacca ctatctacta aagccttaca gcaaaaactt
    21481 ttttctagta agtttatatt tatagtcttt gtaagctcct taatgtactt aagcattttc
    21541 aaatctttat aaatgtattt taataattca caactcacat aagtacatgc aattaagaaa
    21601 gatattttta agtgacttat tcctgtaaaa taaattataa aataagtgct tccagaaata
    21661 aaaatgttta ctagataaaa aactaacgct acatgaacat aatctttttt gctcttactt
    21721 ctaaatgaaa ttaaagttat tatactcatg attattattt taaatggtac agtaaatagt
    21781 atattcattg atggatacaa ataagcaaca gaataggcac ctcctaaact agcccccaat
    21841 aacttatttt ttttaggatt atatctttta gtaagaatag aagtacaact tataataata
    21901 taatttatta ctaggttttc tataacatag tactcaatat acaccatgta tcccccctta
    21961 aaacctttaa acatattata agatagtatg tacaaaattt tatgtcactt ttgatggtcg
    22021 aatccaaaac aaattctatt taaaaagaac aatgatatat gtcttatact ttatgtcgtc
    22081 aaaagatatt tttttaatgc caaacaaata gacttttttg tagaatccaa tatatctagg
    22141 tagaagttat tcgctctact tttggtatat ttacaaaaaa agactacata atttaataat
    22201 atatcaagta aatcttttac ttatataaaa tcaaattata tagtctgtaa attcaaatat
    22261 aaattattgt gctagtaatc catttgcata ttttgcagat tcatttagtg cttgttctgg
    22321 agttatgtct ccagctatca tcatttgaag ttgtttccat aaatattcat atatctctac
    22381 tccatgaggt ccaactgtca atggtctata catatgttta tctcttgtca ccatttcttc
    22441 aaatcttggg tctccttggt atttttcacc tttagcaact ggagctctag gtatttcttt
    22501 gtggaaagct tccattgatt ctttgcttag catatactca agaagtttaa atccaagttc
    22561 tttattttta catgctgaca ttaatgttaa atcatctact gaagcaaaac ttccaactgt
    22621 cttatcttct aatgatgtta catatcccca gtttaaatcc gggaatgatt tatcaaaagt
    22681 acttgtagca gcagaggata gcattatagt aaatgcagct tttcctggtc caaatacact
    22741 ttcaatcatt tcattactat cttttgataa agcatcttct ggaatatact ttttcatatc
    22801 atttataaag tttgcagctt tcaagccttc tgcattatta aatttaactg attttaaatc
    22861 atcattatat atatctccac cagcttgcca taaatacgga taccagttcc agtttaagct
    22921 tccaaatact ttagaacccc aaccttgtgc aagaccccac tggtcgattt ttccatctcc
    22981 atcagtatct tttgttgctt tttcacagat tcttttaaaa tcatcccatg tttttggagg
    23041 tttttctcct aatttttcta gtatatcttt attgtagtac aatacgcctg gattagcagc
    23101 ttctataggt aaaccataaa taccacccat catttttgca tcatctaagt atagataatt
    23161 atctgaagtt cctgattttt ctaaataagg tgttaaatct tctaccgcac ccatttctat
    23221 aaattgagga aacatctctg catacatgta tcctatatct ggaccttcac ctgcacttat
    23281 tgctgttgca tatttttctg cgtagttatc ccatggtact atctgaaatt caatttcaca
    23341 gttattttct ttttcaaatt tttcaaatat cggcttccat gcatctgcat catggtctgt
    23401 taatggtgca gaccatacaa ctaatttttc tttaccctct ttgcctttag aatcttcttt
    23461 ttttgaacat cctgcaagaa ttgatactga tagaatccct accataacta aagaaagaac
    23521 cttttttagt ttaatcatgc ttaatcccct ttcagacttt aatttgtctt tttcctcaaa
    23581 tgtttacatt taattcagat ttaatattaa caaataagat tactcttgtc taatcataaa
    23641 aaactatact aactcctata actatatttt ttttctatac ctattagatt taattcatac
    23701 taaaaactta ctttttaaat tttatcaata tttaaaaata tttttaagtc tagccacaaa
    23761 ctaactatct aaattgaaca aaataaaaag aagtctattg acttctttat aagcttacat
    23821 attatcttct tcttcttagg aatgtaggta tctccatgct ctcatcatca tcttcttcaa
    23881 ttatacttgc ctttttagga ggctctattt tttcctcagc aattacttct tcttcaattt
    23941 cttttacagc ttgttttact gttgtattta atgaagaacg tatgcttgat ttaggtttag
    24001 tatctaaatc taaggcacca ttttgtaatc cttcaaatcc tgtcgcgatt actgtaatca
    24061 ttatttcatc acctaaatct tcttttatag aagctccaaa tataacattt gcttctgggt
    24121 cacaggattc cataactaaa gttgatgcct cattaacttc aaataatcct aagttaggac
    24181 cacctgtaac attaagaagt actcctttag ctccttgtat tgatgtttct agaagtggag
    24241 attgaatagc ttgtcttgca gcatcaattg ctctagtttc accactagca ctacctatac
    24301 ccatatgagc aagtcccttg tctttcatta tagtagtaac atctgcaaag tccaagttta
    24361 ttaacccttc aactgctata aggtctgaaa ttgattgtat accttgtttt aatacatcat
    24421 ctgcaactgc aaaagcatct aacattgatg tatttttttg tactatctgt aaaagtctat
    24481 catttggtat cgttataaga gtatctactt ttgatttaag ttctgctatt ccaccttcag
    24541 cgttcttcat tcttatctta ccttcaaatg caaaaggttt ggtaactaca cctactgtaa
    24601 gtatccccat ttcttttgcc aagcctgcaa ccactggagc agctcctgta ccagtaccac
    24661 cgcccattcc ggctgttaca aagaccatat cagctccttg aagtaacttt actatttcat
    24721 ctttactctc ctcagcagct cttttcccta cttctggatt tgctcctgct ccaagtcctc
    24781 tagttaattt ttctcctatt tgaactttat attcagcttt tgatgtatat aaagcttgtt
    24841 tatctgtatt tactgatata aattcaacgc cttttagttg agcttctacc attctattga
    24901 cagcattgtt tccaccgcca cctacaccta ttactttaat ttgtgcacat tcttctaatt
    24961 ctacgtcaaa gtttagcatc ataaaccccc ttctctcatg attcaaagtt atcgtatgta
    25021 ttaattatat cattttcttc ttttattttg ttaaccttta agtaacatat tccacaaaaa
    25081 cgtaaatttt cctttttaaa tttcttactt atattgtcaa atattactct ttaagtataa
    25141 aataatttac gtatatatta aatgctcttt aatttttacg ttttttgttc ataatattac
    25201 taataatata tcgtctaatt atagataagt tattaaacaa tctcatacca aaaactaata
    25261 cagcaacata gtaaagagaa actcctaact tttctcctat ataagtcaat aatatagcca
    25321 atatagcatt acctatgaaa ccagtaataa aaattacatt atcatagtta tcttcaaaat
    25381 tggattttat cgctccaaaa atagaatcca ttattgcaag aatagctact gacatatata
    25441 tggaataatc catagaatat gtaaatggaa tatagtaacc tactactaca ccaaatgcta
    25501 atcctcctaa aacccataac ataaatcttc acctctttat tttactttga aacacaacta
    25561 cattacaatc ctttttatta atttttttta ctttttcttt atttttttgt atttttcgtt
    25621 ttattttgca aataaattca ctttatttcc attattttcc tgaactttta tattaattcc
    25681 atatatatcc ttaagagatt tagcatatga ttctggagag tttatagctg cactcaataa
    25741 atctatatct cctatagctt ttattataaa tggttgtcca tatgtagtat catttactgt
    25801 aatagtagct cctgaacatt ttatcttact tgttgctagt actctttctc catttataga
    25861 aattgctctt gctccagcct tttttaaatc atttaaaacc ctcaaaatat ctatatcatg
    25921 tataatcaaa tcgtttggat tctgtccgtc ttttaactct ctctcactat ccctcatagt
    25981 aatagttatg cctggccctg taacagttga ataaccactt aactctttaa cttcttcaag
    26041 ctctttttgc ataagtgttt ggatagattc atttccattc ttttttgctt ctttatattc
    26101 attcaaagtt tttttgttct ttttaagagt ttcttttaaa ttttttattt ctttttttgt
    26161 attttctacc tcactttcaa tactttcagt ttgacctaat gttatgtata ctctatttgg
    26221 gtctagtgat tttatataag ttgatatgaa aacgcctaat atgaatgctc ctaatataac
    26281 tattttcttt ttcatactat tatttcccct ctgctttgtt tatatcacta tgaccattta
    26341 tttctatatt gtcttctttg gtcactttta ctttggcatt ataatatgtt tctatttccc
    26401 agacaatacc atactttata ttaagtgccg aagccaatgt atcagaatca ccaattgctt
    26461 ttattataat tggttctttt atgacagtgt cattcatata aagcttgtct tcttttaaat
    26521 acatatatgt attagaaact attctctggt cgtttataga tatggcactt gcttgtgctg
    26581 aatttaattt atttatcatt gacaataata aatcataatt atatagtata ctatcatttt
    26641 tatcagagtt tcctaagtct tttgtagaat ttatctcaat ttttatgcct gttccttcaa
    26701 catctgtata tccagctaat gtttcatatt tttctatttc tgacttaagt atgtcttgtt
    26761 ctccttcatt gtttttgcct ctataagtct ctatatcttt cttcacacta ttaacttctg
    26821 attgtagatt ctctttttct ttttttaaag atttaagttc ttctgtaagt tgctctcctc
    26881 ttttaaaagt tgtcatccct ctattttcta tattaataat tttaagttgt aaactaacaa
    26941 gaacacccaa tacaatactt cctatgatta tacttttatt tataaatctt tttttcaata
    27001 tatcacttcc ttacaattgt ctatccttct ggactataca ctgccaactt tccatagtta
    27061 agatttatag tccctccatt agtattttta ttttgcaggt caatcagaat tttacttacc
    27121 ctagatatat tataatctaa gttatcatca ttagaaagta agatttttat attacttctt
    27181 gtaagcattt ctatattgct ttcttttttt aagtttacat aatttatttt tctataaatt
    27241 ccttcttctt ttaaataatt taaagtttta aatacattct ccttagtttt ataattttta
    27301 aattttatag atttattatc atcaatgcta taatctacat ctactatcaa gtctttttta
    27361 ctttcattag aacctcttag ttcttccaat aaatttcctt ttttatctat ataacaataa
    27421 ttatcttcat cttttaatac tgcaaatatt tctttttctt ttaaacttat aattatctta
    27481 ttgggaagtt ttctttttat ttccacattt tctatatatg gattttttat aagtttattt
    27541 ttcatatctt taaaattgta tgcaaaaata ttttcattta gatttacatt tagttctttc
    27601 attatatttg atttggtcac cctcttattt ccaattacat ctattttctt tacatcaaat
    27661 aaatcacttt ttacaattat acatatacaa aaagataaca taagtataaa aactaaaact
    27721 atcatgacat tattcgtatt taactttctt ctttttttca aatataatca acccctttgg
    27781 ttaataaata cacctttaga gcttgttttt cctacaaaaa aattataata tttaaagtca
    27841 aatttttgca ttttattaca taacatccaa ataaggtatt aaattttata aataaatcaa
    27901 tatttcatca aaataaacat agcatactac atactattta tatatttaaa tctgtataca
    27961 tacaaataaa cccctaattt ataataattt agaaaatcta atatattata aattaggggt
    28021 aaatatttac ttatcttttc tttattccta ttaccttagc ttgaccttct atacttggag
    28081 tcgtttcttt ttttatttct tttacttcct taataacttt ttcttttttt gtttttttag
    28141 aagctgattt ttgtgttgaa ttgtatactt tcattatctc atcatatata aggtctatgg
    28201 cttcaggctt acctatagtt ttacttgcat ttgccatatc aaccaaaagt tctctatctc
    28261 ctaaaagttt aaatactgct gtatttaggc tctctggagt tagatttttt tctaaaatag
    28321 caattcctgc cccttgtttt tctatactct tggcattata ctcttgatga ttttcagcag
    28381 tataagcttt aggtattatt atagatggct ttccaagagc cgttatctca gctaatgaaa
    28441 ttgctcctgc gctacctata accaaatcac ttgctgcaag tgcatttgcc atatcttcta
    28501 agtaaggcac aactttttgg tatggtttaa gatttatatc gctaatactt cccataaatt
    28561 catcataata gcttttgcct gtagcaaata taaaagctat atcttcattt accatattct
    28621 ttattacaag tctcattgca tcatttattt ttcttgaacc tccactacca ccatagcaaa
    28681 gtaccattct tttttcgtca cttattgata gattctttct tgcaatattt tttcttgata
    28741 ataaaatttc ttttctaact ggatttcctg taaaaactaa tttatcttct gctgcctctg
    28801 gaaatctttt atgcgaatct tcaaaacttg taagtacctt tgtaactgtt ttagataaaa
    28861 tcttattagt tacaccagga aaagaatttt gctcatgtat tatggctggt attttcccca
    28921 tagatgcatt aaataaaaca ggtccactaa catatccacc agttcctata actatatctg
    28981 gtttaaattt cttaacaatc tttcttgatt gctccaaacc tttaaaaagc ttaaaaactc
    29041 tttttacatt atcgaaatct atttttcgct taaaaccttg aactgttaca gtctttaatt
    29101 caaatccata cttaggaact atttctgact ctattccctt ttccgtccca acaaaaatta
    29161 tctcagcgtc tggatgctca tctcttattt tgtttgcaat agctatagct ggatacacgt
    29221 gccctccagt tccaccgcct gataataaaa ctttcatcaa atcatcatct cctgttaatt
    29281 aattttgaca tgctttgaga tgtttaacac tattcctaca gctcccataa agatggtgag
    29341 tgaagttcct ccataactta taaatggtag tgctacacct gtagctggca ttgatgatgt
    29401 cgcaactgct atatttaaag ctgcttgtat tccaatttgt gcacctatac ctataacaac
    29461 catacaagca aatacattag aagtcttcaa agctattctt acacatctgt agactaaaac
    29521 tacaaatagc ataataacta ttatacaacc aatcaatcct aactcttctc ctattatagc
    29581 aaatataaag tcattttgtg gctctggtat ataaaaatac ttttgtttac tctttcctaa
    29641 gcctagacca aacaatccac ctgaacctag tgcatataga ccttgtatta cctgataccc
    29701 cttaccaaga gggtcttgaa aagggtctaa aaatgatgta acacgactaa gtctataggg
    29761 ttcagcaatt actaatgcag caaataaagc agccccactc cctatcatag caaatacaat
    29821 tttcatatcc attccagcaa caaatatcat tacaaaagta actagaatta cagtacctgc
    29881 tgttgacaaa tttggctgaa gtattatcaa cgcaaaaaat atccctggaa ctacgagaag
    29941 tggtacaaca ccttttgtca aagattttat tttatcataa tttttttcaa ttaattttgc
    30001 agttaatatt attgtagcaa actttgcgat ttctgcaggt tgaaatgtta aagctcctat
    30061 tcccaaccat ctttttgctc cgtttgcttc tatccctaaa ggggtcaaaa ctaacaataa
    30121 taatactact gctatagctc caattgctgt agcatttttc ttccaaaaac tataatctat
    30181 tcttgatgta ataatcataa ctataaatcc aagtacagca tatattacat tcttttttag
    30241 aaaatagtac gcatcattgt gtttaaatga agattgtata aaacttgcac taaacaccat
    30301 aactattcct acaaatacta aaagcatagt agtgtaaaac actactccat caaattcagt
    30361 cttcatcctt atgtcaattt gttttttcaa attttcttta ggcatccaac taatctacct
    30421 ccattcttcc atttaagtaa gtttagaggt aagagattat tttaaattgt ttacattatc
    30481 tttgaagtct tttcctctta cttcaaaact ttcatacata tcccaacttg cacaagctgg
    30541 tgaaagaagc actatatctc cactttttga aatttcataa gaagtcttaa ctgcttcttc
    30601 catatctttt actatatgta tgtcattaaa tcctttattt ttagcacaat tttctatatt
    30661 tgatgcagtt tctcctaata agaccaatga tttaacatat gactttgcag tttcaagaag
    30721 ttcatcaaaa ttacttccct tatccatccc ccctgctata agtattatag gtctatcata
    30781 agactgtata gcttttatag tggaatctgg attagttccc tttgaatcat ttacatatat
    30841 tacattgtct aaatttctta caaactcttg tctgtgttcc actcctttaa atgtcataag
    30901 tacatccttt ataacttcta aatcaatttt gcagacatat gctattgcta tagctgccat
    30961 acaattttct aagttatgac ctccaggtaa acttacatca tctttattta gaaatttgat
    31021 tttatcatct atatctatta ttatgtcatt attttctaaa tatactcctc catttacttt
    31081 tttagttctt gaaaagtaaa ttactttggc attgcattta tcagctaaag attttactat
    31141 ctcatcatca tagtttaata cacagaaatc ctcaacagtt tggttcataa atatatttgc
    31201 ctttgcttct atgtattttt ccatagtatg gtgtctattt aaatggtcct ctgtaatatt
    31261 taatattgcg cttactttag gtctaaattc atctatactc tcaagctgaa aactgcttag
    31321 ttcagttact aacacagact cttcacttga agtttctata gtatctatta caggatttcc
    31381 tatattacca actacatatg tatctcgttt tgctcttgaa aaaatttctc ctaccaaact
    31441 agttgtagtt gtctttccat ttgtacctgt aatccctata aaaattggat tattcgatag
    31501 tttaaaagct aattctacct caccaattat atacttgcct gaatttttta atttcaatat
    31561 gaatggtagg tctagtggta cacctggaga cactacaacc atatctatat catctacatc
    31621 ttctgggtga tgtcctaata tgtattttat gtcatttata gatttcaatt catcaagtat
    31681 atttctcaat ttattttcat cttttatatc atttacgatt atacttgcac ccaatttatc
    31741 taaatgttta attgtagata taccagtttt tgcaagtcct actaataaaa ctttttttcc
    31801 ttttaagtcc atttttcatt ccccctagcc ctaaaatact gctattatac ttatccaagc
    31861 taaaacaact gttataatcc aaaaaataaa tacaactctt gtttctggcc aaccacactg
    31921 ttcaaagtgg tggtgtattg gagccatctt aaagaatctc tttcttgttg ccttaaaata
    31981 tccaacttga atcaaaactg atagagcctc cgcaaaataa attcctccaa ttataggtat
    32041 tataagcact gagttagtta gaactgaaaa tgctacaact gcacctccta atgccattga
    32101 acctgtgtcg cccataaaca ctctagccgg atatgaatta aatcctaaga aacctaaaca
    32161 tgctccaaca gttgctgctg ctaaaactgc gacttctgta tttccagcaa tagaacttgc
    32221 aaatagcata aagaatacag aaactattaa tgttactcct gatgctaatc catctaatcc
    32281 atcagtcaag tttacagcat ttactattgc tacgattata aacatcatta ttggtatata
    32341 taatattcca acatttatca caaaatctgt aaatggtatc ataagttgtg aagcacttga
    32401 tgatgatgta tactgataaa aagcaacata aaaagataat gcaacttgaa ggattatttt
    32461 ttgatatgct tttagtccaa gtgatctttt tagctttatt tttataaaat catctaaaaa
    32521 gccaataaaa ccaaaacctg caatacatat aagacctact gccatatcat gactaacttt
    32581 tactcttgta agtccagtta ttagaattgc aacaatcatt ataattccac ccatagtagg
    32641 tgttccgttt ttagctagat gtgtttgggg tccatcatct ctaactgtct gaccaaattt
    32701 aaattttcta agcattggta taaatattgg tcctattata attactatta aaaacgcaat
    32761 caatgcggtg tacgtaagct ctgttattcc taacatcata aaactcctct cccttgtcaa
    32821 ttaactcatt agtttaagct tatttattta gatattcgac tattttttct aatctcatgc
    32881 ctcttgagcc ttttactaaa atagtgtctc ctgtttttac taattcattt aacttgttaa
    32941 acacatcttc tctattctca aagtgatata tattggctga attgaatcct aattgttttg
    33001 cttcttctcc aataaacact gaattttcac ctatagttat tataatatca gtattattca
    33061 tagatgattt tccaactaat ctatgaccat actctgaaat ttcacccatt tctagtatat
    33121 ctccaagtat cgctaccctt ctacctttat atcttccaag tatctttaaa gcagcatcca
    33181 tagaatctgg actagcatta tatgaatcat taattattgt taatttttca ttttttatta
    33241 tgtctagtct catttttgtc cctttaaaat tttttaaacc tttttttata taatctaaag
    33301 aaatatttag acacaaacca actaatatag cagacattgc attatatata ttatgttctc
    33361 ctattgttgg tataaatatt tcctcttttt tcccatttat tacacatata aatgttaaac
    33421 tatcctcttc catagtataa ctttcacaat aaacatcatt gtttttatta aagccaaatg
    33481 tttttaactt atatacatgt tctttttctt ttaatgtaga taaaaactta tcatctccat
    33541 ttacaattaa agtatttgtt tcatcaaagt ttgaagtaat ctccatcttt gctttcaaaa
    33601 taccctcttg tgaacctagt ttttctacat gtgataatcc tatattcgat atgactgcaa
    33661 ttttaggatt tactatatcc actaaatatt ttatttcatt gaatccagac atacccatct
    33721 ctattacagc acactcatgt tctttattta gattaaataa agtcaatgga actccaaaat
    33781 gattatttaa gtttttttca ttttttagta tatttaactt tgcagatatg gcagagtaaa
    33841 tcatatctct agtagtagtt tttcccacac tacctgtaac acctataaat ggaatatcaa
    33901 atttttcttt atagtatttt gaaatatctc ctagagccaa agatgtatct tttacctcta
    33961 ttaaatttat atccgaactt tctaatttta ttccattact ttcatttttt ataaaagttt
    34021 tacatccact atcatatgca gacttcataa atgtatgccc atctaaattt tctccaacta
    34081 tggctacaaa tgcattttgg gcatttgcct ccctgctatc tataactata tcacttacac
    34141 agtcattata atctccatat attaacttcc cattagttgc aagtactaac tcttttattg
    34201 ttaagcactc cattattaaa ctcctccttt aaaaccttag ctatattctc ttagcaacaa
    34261 aaggcaatgt ataccgttat atatacattg cctacgataa ctcttaactt tataattata
    34321 tactatattt ctgttttttt gaagatgttt atgggtatat gttaattatc tgttactttt
    34381 tagttttcaa aatatagggt tatacttgag tcttcattaa cttttactcc aggttttggg
    34441 aatatatcct ttacctttgt atcttctgga agttctatat ctgcatctaa gtctggtttt
    34501 aacttcgcat cctccaatgc ctttacagca tctcctattt ttagatttct tacatctggc
    34561 actttaactt gcttcttttc atactcagct ttttcttctt ctttatatac tggtttaact
    34621 cccaaatatt ttaaagagtc attcattatt tctttcacta ttggtcctgc tgtagtacta
    34681 ccaaatgcac ttactcctgt tggttcgtca acaatagcaa gaactactat ttgcgggtca
    34741 tcacaaggtg ctattccaac aaatgaacat atatattttc ctggagcata cttaccatct
    34801 ataacttttt gagctgtacc tgttttacca ccaagtctat aacctggtat atatgctatc
    34861 tttcctccac cttcagttac aactgattct gcaatttcta acattttttt agatgtttct
    34921 ttagatataa cacttcttac tttttttggt tttactgttt cagttatatt tcctttattg
    34981 tcagtataag attttaccac tcttggttgc attaaatctc caccattagc tattgatgat
    35041 atagctgtta taagttgtat tggagttact gatatagatt gaccaaatga tattgtagcc
    35101 aattcaactg gtcctacatt tttttcgtta tacagtattc ccttagcttc tcctggtaaa
    35161 tctatacctg tcttatccat aagaccaaat gattctatat aatcatacat ttttccaaca
    35221 cctaatctgc ttcctaactc aacaaatact gggttgcaag agttttgtac tgcttgttta
    35281 aattcttgtg ttccatgagg tctgtaatgt ctccaacatt taatctttct tcctccaaca
    35341 gttacactac ctgtacatgt gaatttttct ccatctttaa ttactccttc ttcaagagca
    35401 ctggaagatg taataagctt aaatgtagaa cctggttcat atgtatcact tactgctgga
    35461 tttctccaca tttgataata gccttttatt ttatctttat cattatattt ttcaagttct
    35521 tcttgataat atggatatat tggcgttctt gagtcattag ggtcataatc tggttttgat
    35581 gctaaagcaa gtatatcacc tgttttaggg ttcatagcta ttgcagtaac cttttttgca
    35641 ttatttaact cataagcttt ctgtactgct ttttcagtat agtgttgaat tacttcatct
    35701 atagacaaca caagaccatt accttgtaca ggctcataat atttttccat tccttgtggt
    35761 atttctcttc ctgaagcatc agtacttact ataagttttc caggctttcc ttttaacttt
    35821 ttatcatatt gcatttctac accagatata cctgttgcat ctgaagaagt atgtcctaac
    35881 acatatggtg caaaattccc atatgggtaa tatctttgat tatcttctgc cacccatatt
    35941 ccacttaatt tagcatctct tatttgactt gccttatcat catctatcca tctttttact
    36001 tttacaagag ccatattttt tttgcttatt aaagcgtaaa tatctttata atcttcatcc
    36061 aaaatctcag ctaccttttc ggctgcttct tttttatctt ctacttccac aggtttacac
    36121 caaacagtat acttagttac acttactgct aactctttca tatttctatc atatatagtt
    36181 cctcttttgg gttctattgg tatatctctt gtttgttgtt ctagtgcttt tgtactcaac
    36241 caatttccct tcataagttg tagataccca gtcctaataa caaggcaaaa aaacaatgca
    36301 catgctagaa taagaacgag taccagcctt ttcttactta tcctctttac ttttctcaaa
    36361 tctattcccc ctagttatcc acatctatat actttatttg tccatctttt ggatagtcca
    36421 tattgagcaa ttccttagcc tttagctcaa tttcttttat tgatgttttt tcagtttctt
    36481 ttgcctttag ttcctctaat actatctctt tttttcttaa atctttttgt aaataataga
    36541 tatcgtactt catttccgag atttttgaat aaccacatag attcaatatt attactgaaa
    36601 aagttgcaat cagtaaaatg catttagctc ctattttttt cttatttctc tttttataat
    36661 tattcttttt tttattttta tattcattta gattatgtat tttataattt tttttcaaat
    36721 tctcaccccg atagtatata gtttaaattt tcctctatac tatatttgtt attaatcata
    36781 tttcttcctc taaaatttca tcgctaaatt aatacactat tacacaatct aattgtattt
    36841 ttttctatac acaacaaaaa cctataaatt cacttatact tttatatgaa tctataggtt
    36901 agatattaat ttctatttat ttttatcact tctagtattt ttagataatt tcttccataa
    36961 atataatatg taactagcta tctactctct gattcctaag ttctccatta tattacttaa
    37021 taccatctat atctatattt ttatatctaa attttcatta tatatctcaa taacaaagaa
    37081 catttcttat agtgttaatt gttttttaat tgctttacca gtgcaacaaa atatataata
    37141 ctttttaatt aattataata atcttatata taagattatt ctttagcctt ataactactt
    37201 atattttttc tgctactctt agcttagcac ttcttgaacg tggatttact tctatttctt
    37261 cctcactagg taatataggt tttctagtta ttattttcac ctcagattct ttatcacatt
    37321 ggcatatagg taaatgttgt ggacatatac aatctgatgc taaatgctta aatgcatttt
    37381 tcactattct atcttctaat gaatggaatg ttattataca tattcttcca ccttcattca
    37441 ttatagaaga agcatcattt atcatttttg taattactcc aagttcatta tttacttcta
    37501 ttcgtattgc ctgaaaagtt cttttagctg ggtgaggtcc atctattcta gctttcttag
    37561 ggatagcttt tttaattaca tctactaatt ctcctgtagt ttctattggt ttgtttgctc
    37621 tttcttcaac tataaattta gctatacgct tagcccagtt atcttctcca taatctttta
    37681 ttatcttagt taattcatct tctgtataag tatttacaac atcatatgca gaaaactcac
    37741 acctaacatc cattctcata tcaagtggtg catcttgcat ataagaaaat cctctatcag
    37801 cttcatcaag ttgatgagat gaaactccta aatcagctaa tacaccatca attttgtaaa
    37861 ctcctatttt ttctaattcc tcttttatat tttcaaaatt gctgtgaaca aacttcactc
    37921 tactttcata ttcactcaat ctctcttttg ctgtgcttat agcattttta tcttggtcaa
    37981 accctataaa taatccctta tctgacagtt tttttactat ttctttagaa tgtcctgctc
    38041 ctcccatagt acagtcaaca tacacgccat ctggctttat atttaaattc tctatacact
    38101 catttaaaag aactgataca tgatgaaatt ccatagttac ctcccttaaa ttcacttttt
    38161 aaactattct tcactaatat tatttttatt tttctttgat aaataaacat gtgcaattat
    38221 gccaccaata actccaatta gacttataac ttgtgccatt ctaagtggtc ctaacattaa
    38281 actatctgtt cttaatccct ctataaaaaa tcttcctatt gaatataaag ttatataagt
    38341 aactataact tgaccttcat attttttatt ttttctaaat agtaataaaa ctataaatat
    38401 tccaaaatcc catatagact catataaaaa agttggatgt acctttactc catcaaccat
    38461 tattccccaa ggtaaattgg tagcacctcc atgtgcttct ccattaataa aatttcccca
    38521 tcttccaata gcttgtgcta aaggcattcc aagtataact gtatcagcca tttttaagaa
    38581 gttaatattt ttaatcttag tgtatatata accagctaat attccaccaa ttaaccctcc
    38641 atgtatagca agtccaccac ctctaaaatt aaaaatttga gacatatttt gagcatagta
    38701 actccaatta aatacaacat aatagattct tgcacagatt agtccaactg gaattgctat
    38761 tatagctata tttaatacat catcttcttt aattcccact ctttttgctt cttttattgc
    38821 tattaaagtt cctaaaatca ttccacatgc cataagtatt ccataccaca tgatgtctat
    38881 gccaaacagt gtaaatgcta ctctatccat aacgtcacct ctttgtatta attgaaaata
    38941 tttccaaagc aatatgctat aattacaatt aattgtaatt atactaaatt atgataacac
    39001 attaatgtta attctacaaa aaatattaaa atttattcta caactcccta cactatatta
    39061 tatctaatta ctataaaatt ttttaaactg aatctctcat gactaaagtt acaagtgtac
    39121 atagatattt tttaatcaaa aagattgatg catatataca tcaacctctt ctattcctta
    39181 tctatagctc ttaaattttt acctcaattt atataaatat attttataaa tttgttttac
    39241 caaaataaac atttaaaaac ataaactaat acttaattag ttattcttat tatgattaag
    39301 tttctattta ggctctacaa tagaaataac acaatactct tctttaaaat gctcttttaa
    39361 tctttcttca acttcctcaa aagtaatatc tttaataaca tctaaataat ccaatagatt
    39421 tatatcctta aaaacataag atataaaact attacctata aagtttatag aatcaaagca
    39481 cttaataaat gaccctattt ttttcttttt agttctctca aactcttctt ttgataatcc
    39541 ttcttttttt gatttttcta tataatcaag aattatttct tttacttttt taggctcttt
    39601 agaatctcca gctattatgc taaaagcata atccacttga gacgaaaatc cagctccaaa
    39661 attttcattt attaaacctt gcatatacaa atcttcataa agcttacttc cttttttaaa
    39721 taacatccct acaagtatat cagttacaat ctctttacgt aaaagttctt tcccttttaa
    39781 accaacattg ctatctttaa aacctatgtt gaacataggc atagatatag ggaatttttc
    39841 tataacctct ttttctttta cactttctgg ttcttctgga taaaatcttt ctatactctt
    39901 agagagtctg tctactttgt aattgtttga ctttttagtt acatctataa ctttttctac
    39961 atctaagtca ccaacaacaa ataaagccat atttcctgga ttatagaaag tattataaca
    40021 tttatatagc tcttccttag ttatcttata tatactatca acagtacctg ctatatcaat
    40081 tctagcagga taatttacat acattgcctt caagcaatta aagtatacat tccaatcagg
    40141 gtcatcattg tacattttta tctcttgtgc tattatacct ttttcctttt caacattttc
    40201 atctgtaaaa taaggtgttt gaacatagtc aattagatgt tctaaactct cataaaaatt
    40261 ttcagtagca gaaaataagt aggctgtcat tgtaaaatta gtaaatgcat ttgcatttac
    40321 tcctaatttt gaaaatttat caaatgcatc tcctccatca ggttgctcaa acatcttatg
    40381 ctctagaaaa tgtgcaatac cttcattcac tctaattttc ttatcttctc caattggtac
    40441 aaattctaag tcatttgaac cataattagt agccaaaata gcatactttt tcataaaacc
    40501 ccttttaggc ataaaatata catctaatcc attttgcaat ttctcataat aaacttcttc
    40561 tttcaatata tcattaacta ttttttccat agacatctcc tccattaatt tctcaagaag
    40621 tatacagtat caagctctat attttttata gcttcaacta tatctttttt tgtaaccttt
    40681 tctatactag atattatgtc ttgtacttca gaatttgtct ttgccataga ctgagagaaa
    40741 acaaaatcag acataccacc tatattatca gttatagatt tcatagaatt aactaaagca
    40801 agtttactgt tttctaattc ttcatcagat atatcacctg cttttacact ttctacttgt
    40861 ttttttatca attctacagc tttatcataa tctttagttt ctataccaga tgatataaac
    40921 atgatacttt tatacttctc tattgaagag aatatatagt aacataaact ttctttttct
    40981 cttacattaa caaataattt agagtgtgga ccaccaccta agacattgct cccaactact
    41041 aaagcataat atttatctat gtctgcataa tccacatttg ctctataacc cataactaac
    41101 ttaccttgag ttatttccat ttgttcatct ataactttta cctcatccac attttttata
    41161 aaatctgctc ttggtatatt tataatttct tctctttcaa attttagatt tttacttatt
    41221 atatctacaa ctttatcttc atcaaaatta ccttctacaa ctatatctat aggtgatgtt
    41281 ttaagtatgt ttttataatg ttcatataac tctcttgaag ttatactatc tatttcatct
    41341 tcataaccaa attcacttac actatatctc tctcctttac acatagcctc aatacattta
    41401 tcttgcgcat attccttttt atcatttatt attgattgta tcttttctct taaattctct
    41461 ttttcaatat ttaaatattc ttctttaaac ccaccatcta caacaagcgt attatttatt
    41521 acttcattaa aaaattctac tacttcttca aatatactct catctaaata cttttcactt
    41581 atgttaatta ctttaaaact caatacttga cgttctccac gttttacagc atcagctccc
    41641 atagatgaac catataaatc atctaattta ttggatattg ctctagcact aggatattta
    41701 gcgcttccac ttgctattat tgatggtatt agagcatttt ttgtagtttc tttttcatcc
    41761 aatagtctct gaacatataa acttataaga ttcgatttaa acttttctgt ttttatcaaa
    41821 gtaagattaa tattattacc taaatttatt atttttttag tattaaccat atgtacctcc
    41881 tatttttatt taaacatcaa ttttaaaatt gaaatttatt tattttttaa ttacatatac
    41941 tcacatataa aaaccttcta tttaattata tcctttttat tattttctaa aagcaatatt
    42001 tttatttaaa ttaaatacaa atattattta aatcaatatg ctttaaagtc tagtttacaa
    42061 gcttgatata tatgatgtat aatcaacatg tatgtctata attaaaacaa ttttgcaatc
    42121 ctatagattg attgtttaaa gttatataaa gaatataaaa aagaataaga gagaggacga
    42181 ttaatatgaa attaggtata gttggtttac caaatgtagg taaaagcaca ctatttaacg
    42241 caataactca agcaggtgca gaatctgcaa attacccttt ttgtacaata gacccaaatg
    42301 tgggagttgt atctgttcca gatgaaagat taaacaaact acaagaatta tataattctg
    42361 aaaaaatagt tcctactgct atagaatttt gtgatatagc aggtttagtt agaggagctt
    42421 ctaaaggaga aggtttagga aataaattct tatcacatat aagagaagtt gatgcaatag
    42481 ttcatgttgt tagatgtttt gaggatgaaa atgttgtaca tgtagatggt tctgtagacc
    42541 cacttcgtga tatagaaact ataaacttag aattaatttt ctcagatata gagattcttg
    42601 aaagaagaat taataaaact caaaaagctg ctaaggctga taaaacttta ggttctgaac
    42661 ttgatttatt aaaatcaata atgtctactt tagaagaaag taagtgtgta agaactatgg
    42721 aatttacaga agatgaacaa acattcgtaa attcattgga tttacttaca tctaagcctg
    42781 taatatatgc ttcaaatgta tcagaagatg atttagctga taatggagaa aataataaat
    42841 atgttcaaca agttaaagca tttgcagaaa cagaagatgc cgaagttgtt gtagtatgtg
    42901 cacaaataga agcagaaatt tctgaacttg attctgctga agaaaagaaa gagtttttag
    42961 aaacattagg tcttgaacaa tcagggcttg ataagcttat aaaatcttct tatgctttac
    43021 ttggtttaat ttcattctta actgctggtc caaaagaagt tagagcatgg actataaaag
    43081 ttggaagtaa agctcctcag gcaggaggaa aaatacattc tgatatagaa agaggattta
    43141 tcagagcaga aacaatagcc tttaatgatt tggttgagca tggtactatg gctgctgcta
    43201 aagaaaaagg gttggttaaa ttagaaggta aagaatacat agttaaagat ggagatgtaa
    43261 tattatttag atttaatgtt taaaatgatt aatcgtatac actttgacta ttatatataa
    43321 taactaaa
//
LOCUS       DAMKNB010000029        42947 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.030, whole genome shotgun sequence.
ACCESSION   DAMKNB010000029 DAMKNB010000000
VERSION     DAMKNB010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 42947)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 42947)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..42947
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.030"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            84..425
                     /locus_tag="PC494_001726"
     CDS             84..425
                     /locus_tag="PC494_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LytTR family transcriptional regulator"
                     /protein_id="HDF3912228.1"
                     /translation="MKEENFINVEYEDKRFSINSKEVLYIEKQEYEVKIYTESGNYEV
                     GENAPCIRKLLKEENFFKCSNSYIVNLDKCEFYLSNNCIFVNNNFIRILGSERKKKLK
                     KKLEKLYDYED"
     gene            576..989
                     /locus_tag="PC494_001727"
     CDS             576..989
                     /locus_tag="PC494_001727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1653 domain-containing protein"
                     /protein_id="HDF3912229.1"
                     /translation="MLELKNNLGISERKLKYPCIYKHFKGKYYATMGLSKAIDDIENI
                     CEIYGKENLIQNRNKYKLVIRHTEREEDIYVYRDLDGNFYHKKEEDTNDLVLYKTLYD
                     DTGIFARPLDMFLEKVDTDKYVNSIQEYRFEEVYK"
     gene            1191..1832
                     /locus_tag="PC494_001728"
     CDS             1191..1832
                     /locus_tag="PC494_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HDF3912230.1"
                     /translation="MGNTFYIVRHGQTDWNILGKTQGHGNSDLTPQGIEQAKELSEDI
                     GKYSIDYIFSSDLGRAMQTAQILGDKLNIEVQKTEALREMGFGVWEGLLIKEIQKDYS
                     DIYATWRNEPHLVNIPEGETLKIIKERVDAFIKELNEKYDNKNIILVTHSITLRVMLL
                     SFLESGMENIYRIKQDNTALNIVEFKDYGPVIVKMNDTSHIKNHVKINNSALE"
     gene            1856..3109
                     /locus_tag="PC494_001729"
     CDS             1856..3109
                     /locus_tag="PC494_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HDF3912231.1"
                     /translation="MSKVIVVGGGASGMMAALSASKNNNEVILVERNGELGRKLRATG
                     GGRCNFTNNREIEDFFDKVVSNKKFLYSSFYTFTNKDLISYFESRNLEYKIEEENDHK
                     VYTKNDKSIEVIEVLNKDLLNHNVKIMYNKKVIDIITEEIALKDDSNKDKSKYLIKGI
                     ILDNGDKILGDKVIISTGGVSYSKTGSDGSMYKILKKHGHTLNKLYPALVPLTIEEKW
                     IKDLQGISMKNVEISCKIKKRKISKSGDMLFAHFGITGPCVLIMSSYINKIIEKEKVE
                     LNIDFLPNLSTDEISSIIRAFPNKNVLNNLKQILPQNFLKEIFSLLSLVDKKASDLSK
                     ADEIRIIEYIKNMKLTCNGTTGINTGMVTSGGISVKEINSSTMESKLVKNLFFTGEVI
                     DIDAETGGYNLQIAFSTGYLAGISV"
     gene            3155..3805
                     /locus_tag="PC494_001730"
     CDS             3155..3805
                     /locus_tag="PC494_001730"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HDF3912232.1"
                     /translation="MGNLVIAVDGPAGAGKSTIAKIVAKKLNINYIDTGAMYRAVTYK
                     CLKSGIDVNNEKEVIQIAENSDIDFKDNNIYLDKEVINEEIRTIEVSNNVSNVAKIKE
                     VRQLMVEVQRKIGMKNSVILDGRDIGSYVFPDADYKFFLVATPEERGNRRYKELCNKG
                     YNTTLEEVIEDIIRRDEIDSNREFAPLVKANDALEIDTTGKTIEEVVEEVVSKINL"
     gene            3856..4452
                     /locus_tag="PC494_001731"
     CDS             3856..4452
                     /locus_tag="PC494_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HDF3912233.1"
                     /translation="MNFYRFVINIFKGFSKIFFKYEVIGAENIPDRGNIVIASNHKSN
                     LDPIFLAAAIENREIAAIAKKELFKVKPLGFILKKLHVMPINREKPDVSTIKTILRSV
                     RDGYVLGIFPEGTRIKGDSFGKAKAGLSVFTIKSKSKVVPVSIISKYKLFSKVIVYIG
                     EPISFEEHFKEKLSNDDHERISQEILEVIKQNYFKYSK"
     gene            4465..5304
                     /locus_tag="PC494_001732"
     CDS             4465..5304
                     /locus_tag="PC494_001732"
                     /EC_number="1.17.7.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-3-methylbut-2-enyl diphosphate
                     reductase"
                     /protein_id="HDF3912234.1"
                     /translation="MNIKIAKNAGFCFGVKRAMKMAWDEVEKNDSGIYALGPLIHNKQ
                     AVAKYEEKGLKTVNEIDTIPNHENMIIRSHGVPENIYKEAKDKKLKIVDTTCPFVKKI
                     HTVVSEYHNKGYEIIVIGDMKHPEVIGINGWCENSAIIIKTLEQMENMEFDNSKRYCL
                     VAQTTINPELYISIVNKLSDKLEEIVFNDTICSATKTRQESAKELAKEVDCMIVIGGK
                     HSSNTQKLVKVCEDLVPTFAIETKDELDVNTLKKYKNLGITAGASTPNWIIEEVVTFL
                     ENL"
     gene            5549..6703
                     /locus_tag="PC494_001733"
     CDS             5549..6703
                     /locus_tag="PC494_001733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenic efflux protein"
                     /protein_id="HDF3912235.1"
                     /translation="MEMLISASEEAFLHVGSMIGFFILLFGYINYKTSGNFTNIISKN
                     RKFQPLIGALIGAIPGCGGSLAIMPLYINGKLSFGAIIASLIASMGDAAFVLISSNIK
                     MYFFVTIVSTITGIITGQLVDYFKLEEKLGLKNRRKSDKYDISKNNPKENKEQHNHDE
                     IILDTLAKSHGNTNRLAFIITHGKGYKIYIGIIVIGFIFMSLAHSGLNLPIIEKLHSL
                     EEVIAVIGILFSIIYMWCFKKVFKNSNQKEEENKKISLREMLIHSVGEISFVITWIFI
                     AYLIYDLIILILGGDEYLVKLVLSTGVISVFIGAGLGLIPGCGIQIVLMSFYLKGTIP
                     LGAVIANSISQDGDALFPLLAMDKKSSLWAMIITTIPAILVGMIVYAFLG"
     gene            7009..8706
                     /gene="ade"
                     /locus_tag="PC494_001734"
     CDS             7009..8706
                     /gene="ade"
                     /locus_tag="PC494_001734"
                     /EC_number="3.5.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine deaminase"
                     /protein_id="HDF3912236.1"
                     /translation="MGNLKRQCDVSSGREKADIVLKNGTIINVFTEELITGDVAIVGD
                     TIVGIGDYKGNVEIDCSNKYISPGFIDAHMHIESTMVMPIELSKKLLKSGTTTIIADP
                     HELVNVKGVSAIDFLLESTKDIPLNVYIMVPSSVPATSFETNGVGKFSAKDMESYVNN
                     PRILGLGEVMCFNDVINSENEILDKLELFKNKVVDGHAPNINGKSLQTYVCAGIENDH
                     ECITFDEVYEKLRAGLKILIREGSAAKNLKSIVSGMLKHNLPIEEFMFCTDDKHLDDI
                     EKQGHIRWNIKCAIDLGMEPVRAIKVATYNSAKAYGLRKIGAIGAGYKADIVVLNDLD
                     KMEVDSVYKDGNLVNEEMFSNYNYEIKDKELLNTVKFKYINKEKIQLKVSEKNYVMEI
                     VPYQILTNKVYESLPCADGYFVPNKEYSKLCVVERHRMTGNVAIAPLKGFGIKNGAIA
                     TTVAHDSHNIIVAGDNDDDILVAINYLKEIQGGYVIVSNGKVLAHLSLQVAGLISTFT
                     AEEVQEITDNMLEIARKMEVPEYVDPFITLSFMALPVVPQIRLTDLGLFDVEEFKFI"
     gene            9058..9522
                     /gene="bcp"
                     /locus_tag="PC494_001735"
     CDS             9058..9522
                     /gene="bcp"
                     /locus_tag="PC494_001735"
                     /EC_number="1.11.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002586316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-dependent thiol peroxidase"
                     /protein_id="HDF3912237.1"
                     /translation="MLSIGTKAPEFTLEDKDGNKVSMSDFKGKKVVVYFYPKDNTPGC
                     TRQACAFRNAYDGFKKEDIQVIGISKDSIKSHQKFAEKHELPFILLSDPDLVAIKAFD
                     VWKEKKMYGKTALGVVRATYIIDENGIIEKVFEKAKPDTNAQEILEYLEKQE"
     gene            9532..10275
                     /gene="yaaA"
                     /locus_tag="PC494_001736"
     CDS             9532..10275
                     /gene="yaaA"
                     /locus_tag="PC494_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide stress protein YaaA"
                     /protein_id="HDF3912238.1"
                     /translation="MIIMLSPAKNMKNIEVFDRDLSLPCFIDNTKEIVENIKTFGIED
                     FKNKMKINEKLAVLNKNRFESIKFDRLGNPAILTYDGIQYKNIEAENFTRKDEEFANS
                     CIRIISGLYGVVKPYDSIYEYRLEMQTKLQVGEFKNLYEYWGNRIYKELIKEKTAIVN
                     LSSNEYSKSIEKFIKDSDTYITCTFKVNKNGILKVESTQAKKARGMMTKYIVKNRIRD
                     IEELKKFDLEGYKYKENLSNNSEYIFVKE"
     gene            10403..13060
                     /locus_tag="PC494_001737"
     CDS             10403..13060
                     /locus_tag="PC494_001737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HDF3912239.1"
                     /translation="MENHKQMPWHSRATHEILESLDSSEEGLTDTEAEKRLKENGLNE
                     LRKKPPRTTLQMLWSQITDAMVMILIGAAILSLIFGEFTEAFVILIIVTVNAVIGIVQ
                     EKKAESSLEALKNMNSPTARVMRDGEENVIPASNLVVGDIVFLEDGAMVPADLRLIET
                     SSLKIQEASLTGESVPSEKDADTILPKECVLGDRSNMAYTSSIVTYGRGVGVVVATGM
                     DTEVGNIAHLLDSQDDFDTPIKRKLNTVGKTLSVIGIIVCVVIFAIGAFYQRPLLPMF
                     MIAISLAISIIPEGLPATATIVMALGVQRMAKRNALIRKLPAVETLGGATVICCDKTG
                     TLTLNKMTVTHIAVNGDFESGKVTSIDTASEKHPLVYKEIVYAGALCNDACINPDKTD
                     EILGDPTEGALIFMAKKFGIDQEALEEEYPRVFEQPFDSDRKCMTTVHNIDEKIIAYT
                     KGAVDEILDLCTKILTSKGERNITEVDKKNIHELCLNMSKDALRVLGFAKREISSIPK
                     EDSENIEYDLTFIGMVGMIDPPRTEVIDAVSTCKEAGIRTIMITGDHKVTATTIAHEL
                     GIWSEENTVISGDELDNLSDDELDEAVKNTTVFARVSPFDKLRIIQSLKRIGEVPAMT
                     GDGVNDSPALKSADIGIAMGISGTDVAKDSSDMILMDDSFTTIAYAIKEGRRVYRNIQ
                     KVIQFLLVGNIAEILTLFVAILLNWDTPLLAVHILWVNLATATLPALALGVDPPSRNI
                     MKHQPVKSTTLFEKNLIQRVVTQGVFVAIMTILAYKIGLNIENHSVGQTMAFCVLAFS
                     QMLRAFSQRSNTDSMFNRNNGKNPFLLISFLTSAFLIAVILFVPVFRNAFNLTVLNNL
                     EWLITIVLAIMSVIQVEVGKIIKRKKLKK"
     regulatory      13114..13216
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00162"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="SAM riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF00162"
     gene            13326..14591
                     /locus_tag="PC494_001738"
     CDS             13326..14591
                     /locus_tag="PC494_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-acetylhomoserine
                     aminocarboxypropyltransferase/cysteine synthase"
                     /protein_id="HDF3912240.1"
                     /translation="MYNKETICVQGNYKPGNGEPRVLPLYQSTTFKYSSIDQLAELFD
                     LKVDGHIYSRISNPTIQAFEEKISLLEGGVSSVAVSSGQSANMLAVLNICKSGDSILC
                     SSKVYGGTFNLLGPSLKKFGIDLISFDLDSSEDEIVELAKENTKVVFAETLANPTLEV
                     IDFEKIANVAKRINVPFIVDNSLASPVLCNPLKYGANIVTHSTTKYLDGHASSVGGII
                     VDGGNFNWDNGKFPELVEPDPTYHGISYTQKFGNAAYATKARVQLLRDYGNCLSPFNA
                     YLTNLNVETLHLRMERHSENALKIARFLEKHENVDWINYPGLEDNKYYENAKKYLSRG
                     CSGVLSFGVRGGLENAKKFVEKLQIASLVTHVSDVRTCVIHPASTTHRQLTEEQLIAS
                     GVLPSLIRLSVGIENVEDLIADLNQALNF"
     gene            14621..15511
                     /gene="metA"
                     /locus_tag="PC494_001739"
     CDS             14621..15511
                     /gene="metA"
                     /locus_tag="PC494_001739"
                     /EC_number="2.3.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine O-succinyltransferase"
                     /protein_id="HDF3912241.1"
                     /translation="MALILPKGLPVINKLLDEGIDVIYKEDFKKELKYEENIDTKIAI
                     LNLMPIKIDTELDLLRRIDKTGFNVSVEFIKISTRESKRSCNEYVKEFYKTFDEAKGE
                     YFDGFIITGAPVEQMEFEEVDYWNELEEIMDYSKRKTKSTLYICWAAQASLYKYYNVK
                     KLPLSQKCFGVFKHKVDKDSKIVDGFENEFFAPHSRHTTVNIEALKENKELSIVSHSK
                     EAGPYIITNSRDVFVMGHSEYDKYTLDKEYKRDINKGDKISIPQNYYINDDPSEEPTV
                     KWKKHSELLFRNWIKNYLIQ"
     gene            16002..16445
                     /locus_tag="PC494_001740"
     CDS             16002..16445
                     /locus_tag="PC494_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HDF3912242.1"
                     /translation="MDEMSFKKELLELTRDINMKFTTLLSDFYQPLGITAVQALILSE
                     LCEHGEKKISDLGKNLNMTNSNVSVICQRLEKNGFLNRIRDIEDQRIVKVKVTNKSLD
                     IQEHISSSIFDSYFENMTSEKLQDMEDIIEGLEKLNKLLTYIDCK"
     gene            16476..18293
                     /gene="ftsH"
                     /locus_tag="PC494_001741"
     CDS             16476..18293
                     /gene="ftsH"
                     /locus_tag="PC494_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HDF3912243.1"
                     /translation="MDEHKPQKRSALYYYTVIIIVVMFLNALIFPSLMDKKMVEIDYG
                     KFLTMLDTGKVKSVEIENNRIAINPSSSKDKNIYITGRMDDPELVDRLKNAKVEFTKV
                     IPKENSPLLSILLTWIIPIGILMLFGNLMMKSMQKRMGGNAMQFGKSNAKMYVSAQSG
                     KRFNDVAGQDEAKEALTEIVDFLHNPEKYKKIGAQMPKGALLVGPPGTGKTLLAKAVA
                     GEANVPFFSISGSEFVEMFVGMGASRIRDLFKQAKEKAPCIVFIDEIDTIGKKRDNGS
                     GLGGNDEREQTLNQLLSEMDGFDGGIGVVILAATNRPDSLDKALLRPGRFDRRIPVEL
                     PDLGGREAILKVHAQNVNVSSDIDYNAIARSTSGASGAELANIVNEAALLAVKSGRDI
                     VEQQDFEESVETVIAGYQRKGAVISDKEKKIIAYHEIGHALVAAMQKHSAPVHKITII
                     PRTSGALGYTMQVAEDESVLMSKEEAIDKITTFTGGRAAEEVIFNTCTSGASNDIEQA
                     TKIARAMVTRLGMSEEFDMVALETVSNQYLGGDTSLACSSDTAAKIDEEVFKIVKACH
                     KNAIEILENNIDKLHELANYLLEKETITGDEFMEILNLN"
     gene            18471..21173
                     /locus_tag="PC494_001742"
     CDS             18471..21173
                     /locus_tag="PC494_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase KdpD"
                     /protein_id="HDF3912244.1"
                     /translation="MDRPNPDILLEKIKNEEEKLSRGQLKIFFGYAAGVGKTYSMLES
                     AQNLKKVGVDVVVGYIEPHTRPETLALLDGLEILPVKDIEYKSIKLKEFDLDAALARK
                     PEVILVDEFAHSNVAGLRHTKRWQDIEELLLAGINVYTTVNVQHLESLNDIVEIITNV
                     SVKETIPDKFLDTNTQLELIDVEPDVLLERFNEGKIYKKEQATRAKNNFFIKDNLVAL
                     REIALRKTAERVNKEVQMTRLSKGDVTVIPTSDTLLACISPSPSSAKVIRTASRISDS
                     TFAKWIALYVETPNTARLPFDEQKQLQNNLKLAKKLGGEIIVLHGENIIEQILRIAKL
                     RNVTKIVIGRNHSSNKRFSKRFKKDIVDKLIDEVDYIDIHIIPYKFASDVKYKPKKDK
                     SSIKSKFKISKVDFIKLIFITLMISILAYAVQSMGFIRENILLIYMLGVVLVSMWTKG
                     YSTGIISSVFNIVLLNYFFTAPLYTLSIADSNYIVTLVVFSIVGIITSTLTSKIQHEA
                     ETAAKREENTKMIYQIIKGFLRLSNKDDIVNKGIELLSLSLSRDVICYLNVDKHNKSK
                     LYKKNTNNKDKNDLDSEDEKAVASWVLSNSTVAGNDTDTLPGSKGYYIPIVGMNLTLG
                     VVGISCIDSKLDTEDISLIETIIAQMAIALDREILSEAKENTNLEIERERLRSNLLRA
                     VSHDLRTPLAGISGAVSTIIKNKGTIGQDIIDELLSGVYEDTQWLIRLVENLLSMTKI
                     DEGKLEVKKHSELVEEIISEALQKIKKRIENALIDINIPEQILFVPMDAKLIEQVLIN
                     LIDNSLKYSKEDCKIEINVYEKDDYVWFEVSDNGPGISKELKKHIFDRFFTGEEGAKD
                     SRKGVGLGLSICKSIIQAHKGEIMVENNKDKGSTFKFSLPKENE"
     gene            21207..21905
                     /locus_tag="PC494_001743"
     CDS             21207..21905
                     /locus_tag="PC494_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF3912245.1"
                     /translation="MSKKLILLVEDDKTIRKFISTALLTQDYDVKEAITGKEGISIAV
                     SYSPDVVLLDLGLEDMDGIEVIKAIRQFSNIPIIVVSAREQDRDKVEVFDAGADDYLT
                     KPFSIVELLARVRVAFRHSQVEAQQKDDVKSTFEVDKLLIDFDKRKVIVDDVEVHLTP
                     IEYNILSLLAKHHGKVLTHNFIIKEIWGSVIGNETKSLRVFMATLRRKIEKQPANPRY
                     IITEVGVGYRLNDE"
     gene            22262..23218
                     /locus_tag="PC494_001744"
     CDS             22262..23218
                     /locus_tag="PC494_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CorA family divalent cation transporter"
                     /protein_id="HDF3912246.1"
                     /translation="MYILNLNTRETIEDFRDKFYVAENSYLILSAPKNLKLLKETLDI
                     DEITFNDCLKFDEITKLDLFDNYDFLSLNTFELRDGEAVIEEVNMYLSDNFILVVVNE
                     EHFLFEFVKNIILKNSQLEKNPVINLFKINYLILREVIKNGFESLEKVEELILQIEDE
                     MMDNINKNHVSRISDVRGLTRIIVKNTRPLLYIGDRIVKENIRYLKYSNVKKYNLENF
                     QGIDFGIDKLYNFALSTRELADKLLDIYSSRVGEKTNNLITKLTLLTAISAPLTIITG
                     IYGMNFRYMPELNWIYGYPATLFFMLCIIFVGIIIFKIKKLL"
     gene            23395..23550
                     /locus_tag="PC494_001745"
     CDS             23395..23550
                     /locus_tag="PC494_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3912247.1"
                     /translation="MKGILKELTAKLYSFFYFMFWGFYFSAGYFFYKNICTSFLVRPY
                     FSDFEHK"
     gene            23680..24693
                     /gene="aroF"
                     /locus_tag="PC494_001746"
     CDS             23680..24693
                     /gene="aroF"
                     /locus_tag="PC494_001746"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003452924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HDF3912248.1"
                     /translation="MIVVLKMGADKNEVKKLIEAIGREGVEVNPIDGTELTVLGLVGD
                     TSKIDAKRIEANKVVEKVMHVVEPFKKANRKFHPEPSIINVNGMEIGSKKIAMIAGPC
                     SVETEDQIVSIAKDVKKSGAGFLRGGAFKPRTSPYAFQGLKYDGLDLLKKAKEKTGLP
                     IVTEIMSTQDIDIFEENVDVIQVGARNMQNFDLLKELGKTNKTILLKRGLSATIEEWL
                     MSAEYIMAGGNENVVLCERGIRTFETYTRNTLDLSAILAVKKLSHLPVIVDPSHAAGK
                     SWMVDSLSKAAIAVGADGLIIEVHNDPAHALCDGKQSIKPNEYDELISELKTIASAVG
                     REI"
     gene            24715..25779
                     /locus_tag="PC494_001747"
     CDS             24715..25779
                     /locus_tag="PC494_001747"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HDF3912249.1"
                     /translation="MEEKLLVNLKENSYNIFIKKNILKNIGEEIKKIYFGNKIFIVTD
                     ENIAKLYLDKVKNNLSESGFEIKSLILKSGEETKSFNTLPKIYDSLLDFKLTRKDLII
                     TLGGGVIGDLGGFAAATFLRGISFIQIPTSLLAQVDSSVGGKVGVDLERGKNLVGSFY
                     QPKAVFIDPNVLLSLPEKFYRDGMAEVIKYGCIKDKTFFDKLLSLKNREEVMQHIEYI
                     IHKCCFIKKTVVEADEKDFGDRMLLNFGHTLGHAIEKYYNFTGYTHGEAVAIGMYKIT
                     LESEKIGITKKGTSELIKSILMNYNLPYEIELRDNKSIVDAISLDKKNLGDTLKIILL
                     KDIGESIIYNTTSKFFQEVR"
     gene            25779..27092
                     /gene="aroA"
                     /locus_tag="PC494_001748"
     CDS             25779..27092
                     /gene="aroA"
                     /locus_tag="PC494_001748"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HDF3912250.1"
                     /translation="MGSLKIYPSKLSGDVKIPPSKSMAHRAVICSSLSNGKSRISNID
                     FSDDIIATIRAMTSLGAIIEKKEDILEISGIFSKEGILNRENQLNQPKLTIDCNESGS
                     TLRFLVPISLAFDGIKRFIGRGNLGKRPLDTYYEIFDRQNIKYSYKENQLDLIISGKL
                     KPDEFRVKGNISSQFITGLLFILPTLESDSKIIITTELESKGYLDLTLSTIKDFGVEI
                     INNNYKEFIIKGNQTYKARDYKVEGDYSQGAFYLSADAIGEDISILDLKEDSLQGDSE
                     VVEILSRMGMEILREGNKIKGITNGLNGTLIDASQCPDIIPVLSVVASLSIGRTTIIN
                     AGRLRIKECDRLHAINVELSKLGANIEEKEDSLIIEGVSKLNGGVEVWSHKDHRIAMT
                     LAIASCRCDKPIILKDFECVSKSYPHFFKDFKMLGGRIDEWNMGK"
     gene            27070..28149
                     /gene="aroC"
                     /locus_tag="PC494_001749"
     CDS             27070..28149
                     /gene="aroC"
                     /locus_tag="PC494_001749"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HDF3912251.1"
                     /translation="MSGIWGNNLKVSIFGESHGNAIGINIDGLPSGIELDLDNIDKEM
                     KRRAPGKNSISTSRNESDIPEILSGYFNGRTTGTPLCAIIRNSDTRSKDYGELKNLMR
                     PGHADFTGNVRYSGFNDYRGGGHFSGRITAPLVFCGAICKQILSQKGIEIGAHIKKIK
                     NIEDMSFDYVNISKQQLSNLQTLELPLLDLSKEEAMKNTIIDAKNQGDSVGGIIECAV
                     VGINVGLGNPFFDSVESTLSHLLFSVPAVKGVEFGLGFELADMYGSQSNDEMYYEGNQ
                     VKSKTNNNGGIIGGITTGMPIIFKVAIKPTPSISRQQNTVNIKDKKDDILYIKGRHDP
                     CIVQRAIPVIEAVTAIGIFDLMKGR"
     gene            28152..29348
                     /gene="pheA"
                     /locus_tag="PC494_001750"
     CDS             28152..29348
                     /gene="pheA"
                     /locus_tag="PC494_001750"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HDF3912252.1"
                     /translation="MEDLTRYRNEIDNIDKELIQLFEKRMNTVLEIARHKMKNNTTIL
                     QKDREEKVLSRAVDNLDNKAYSQETVQFFNSIMEISRGLQKRLIDNDGEQKIEFSLDS
                     SNKKFDLSNVNRYKSLKDELNKKNILVGFSGKSGSFTEEALNKFFNKKISKKQFKEFE
                     DVFIALKNKEINYGIIPIENSSTGAISETYDLLRKYGFYIVGEECIKIDQNLIGIKDT
                     KLEDIKEIYSHPQGIGQCSEFLKQNSTWKLIPFNNTATSAELVRKLQDKTKAAIASKK
                     AASIYGLEIISPCINDIANNYTRFVVISNQIHIEEESNKMSVVFSVEHEAGKLYKVLG
                     YFAKNNINMTKIESRPMKNASWRYFFYIDFECSIYNSKVYDLLELIEHNTAYFKFMGV
                     YKNKTE"
     gene            29395..30204
                     /gene="aroE"
                     /locus_tag="PC494_001751"
     CDS             29395..30204
                     /gene="aroE"
                     /locus_tag="PC494_001751"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HDF3912253.1"
                     /translation="MNFFGLVGEKLSHSVSPQIHKRVFEILNIESAYKNFEISKEDIS
                     KLDGAIKLLGIQGVNVTVPYKERIMKYLDFISPEAKRIGAVNTILLRENMLYGYNTDY
                     FGLDSMFKMANIDVQGKVAVILGTGGASKAALTYFIDSGIEKLYVSTRKKDDKKLLNS
                     KAILIDYEELKHIKGDIILNATPVGMYPNVGISPVSKSIIQNFDILIDLIYNPGETEF
                     LRIGNSMGKKTCDGLYMLVGQAIKSQEIWQDTKIDNSILDVIYNELKLEFL"
     gene            30216..30749
                     /locus_tag="PC494_001752"
     CDS             30216..30749
                     /locus_tag="PC494_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HDF3912254.1"
                     /translation="MINKTKEKLILIGMPGSGKTTIGKLLAKEYNCSFCDMDDYIIQI
                     SQKSIAELFSEGEDIFRNYETQACRELSISDKTVISTGGGVIKKDVNMEILKETGIII
                     FIDRPIQKILEDININSRPLLKNGKDRLYNLYNERINLYKKFSDIEILNDKSLNNAVY
                     NITNAVSENFKFDFKEK"
     gene            30770..31609
                     /locus_tag="PC494_001753"
     CDS             30770..31609
                     /locus_tag="PC494_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HDF3912255.1"
                     /translation="MNIVIVGLGVIGGSFAKALKKAGYENVFGVDVDLETLKKAEKSK
                     IIKKGCTTGKELFKKADLIILSIYPRLVVDFLNNNKNFFKKGTIITDTTGIKETLIND
                     VLQIIPDDIDFIFGHPMAGREKKGIDFASEQVFNGANYIITPTGRNNIKNLELVENLI
                     LEIGFKRVKKLTSQKHDEIIAFTSQLPHVMAVALINSDEEGRDTGKFIGDSYRDLTRI
                     ANMNEDLWSELFLGNRDNLLKVIENFESEVNLVKEAIFNNDKNKLIEYFKKSSIRREA
                     LEK"
     gene            31877..33358
                     /locus_tag="PC494_001754"
     CDS             31877..33358
                     /locus_tag="PC494_001754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional diguanylate
                     cyclase/phosphodiesterase"
                     /protein_id="HDF3912256.1"
                     /translation="MKKNRLIAKNISIAFIVLFFFSVFTFFYVGNINRVLEYETNDII
                     TVTIAGWIILSFLFLGIIIYILYSKANSQKTIEKVAYTDFVTGYSNWRKFELDVTNLL
                     KKTSQNNKYAMVIFDIDKFKAINDIYGHKKGNLILKDIADTLNELTNINETFARVSAD
                     SFNILLTYNKKEDIINIIKKIMANNELVNLSFGIYEIKDKDLSVSVYSDRASLAKSSI
                     KNNSDVNFAFFNDKLREKLLLEDKIEKEMEYALESGQFVMYLQPKYNIKLDKFCGSEA
                     LVRWQYTEKEVIYPGDFIPIFEKNGFIRKIDMYILEQACKEIRSLFDKGISPLPISVN
                     FSRVDFFKKDFIENIVNICDRYKIPYSLIEIEITESSMFGDTDTLFNVSRNLQDIGFI
                     VAMDDFGSGYSSVNMLKNIPLNVIKLDRGFFVDDKDVDKSQIVIKSIVSLIKQLGIRV
                     VAEGIETRSQIEMLKKANCDIVQGYYFSKPLPIKEFEKLVYKI"
     gene            33391..36828
                     /locus_tag="PC494_001755"
     CDS             33391..36828
                     /locus_tag="PC494_001755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PAS domain-containing protein"
                     /protein_id="HDF3912257.1"
                     /translation="MIRAKSLKNVLSIVLIFLFTIISFSDFAFKTNVQEEENSKINLR
                     EISLQSSNAIKIKLDSSLSFIKSVANMVSYFNTIDNSKIVPLLANISKESDFQRISIV
                     SPDGISHTSDGKIINVSKYQYFKKAIKGESNISEVVKSPIDGKDTFVIATPVFNKNNK
                     IIGVLYGSYYNDKLAEFIDITSFNSEGYIDIFESSGQFVLKSSHTNKLIKSSSNIYDI
                     FKKASFDDGYSYKKIYEDTKNNKSGFTSYEYKGENRYATYTPIGVNDWYVISVIPQYT
                     VRRNIDKINQLAFSLIFKVFLLFIMLIIYIIYKNNKSQKDILKANKEISSITNSIPGG
                     VQKCTLGETCNINFLSDGFIELFGYTREEIKTLFNNDFYSLIHKDDVERIKKEIFKQL
                     YKNKTIELEYRIITKNGNTVWVLDKGELITEPDGKEYFCCVTVDITRTKQLEQEMEQK
                     NLELEMISENVLGGIIITEFNDDFTIKYANSGYLSMIGYTREQLENELKYKACNLVFY
                     EDKKKALESIQHQLNTKGIAVYQHRIRRRNGNIIWVSIKGRLIVDDDGIEKGIWILND
                     ITDLKNAEQKLKINEERFRIALKQTSNTIFEYDIKTKSLLNTSKELDKYNIYKITKNV
                     PYSLVESGVIHKDFSDDFINMYENVINGAKKASCVVKMKLPDENYIWNKVTLTTIFDE
                     DGNPVRAIGIQEDISKQKEAEIRYNQEGKYHSAILSEAMITYEINVSKDTFIKGNESW
                     QKPFGIKPDNNYSQMVKTIANSIVHKDNKETFLNTFLCENLLDAYKNNVTEIKLEYRR
                     MNQENKMIWVICTMHLIKDSITNDIKALAYVKDIDKQKNEEIRLKLKAERDTLTGLYN
                     KGTTEKLINDFLNSEEASLGMHAFLIVDIDNFKSVNDNLGHVFGDKVLFEVSKNLKPI
                     FRKDDIVGRIGGDEFIVFLKNIQSFENIKKKAEKICDIFRNSYTENKKTYKISGTVGI
                     SFVPEHGTVFEELYKKADIALYYAKSKGKDKYALYNDCIYQNELENNISDNNIKLADK
                     CEKSKPVLKEILDSIDNYIYIVNPNTYELLFINNKVSRLDLEIKLGETCYKSLLKSDR
                     PCNNCPLNGLEENKHSKFKIETNTFGKNISIASWINCIDGEYNCLIECIDSSLYKNK"
     gene            36846..37592
                     /locus_tag="PC494_001756"
     CDS             36846..37592
                     /locus_tag="PC494_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HDF3912258.1"
                     /translation="MLNSITLILGIIFTIYYFYLKIVFGGISFSEIFLVVGIVLIIYQ
                     IFKKKIKEKKVFYRVLKIIISIFLIVFVVTESLIIFYPKNSLESKSDYLLILGASVKK
                     TTPSTTLKGRLDTALKYLKINDNCYVVVSGGKGSGEKITEAKAMKDYLIKNGIDKNRI
                     IEEDKSTNTYENFKYSKLKIEEHSQGKLSDLKVKIVTTDFHVLRSKILAYRNGYKNTS
                     FYASKSKLSFVPTYYTREFFALWKTIIFDR"
     gene            complement(37541..37849)
                     /locus_tag="PC494_001757"
     CDS             complement(37541..37849)
                     /locus_tag="PC494_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine 5'-phosphate oxidase family
                     protein"
                     /protein_id="HDF3912259.1"
                     /translation="MNFFKENSTFYFATVEDNKPRVRPFGFIMDYEGKLYFGIVKYKT
                     SYKQLLVNPNVEISTTSKVGKWIRIKGIEKTRYEFISSLFIYYLSKMIVFHNAKNSLV
                     "
     gene            38653..42795
                     /locus_tag="PC494_001758"
     CDS             38653..42795
                     /locus_tag="PC494_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014466370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF11 domain-containing protein"
                     /protein_id="HDF3912260.1"
                     /translation="MATVSGQIVFDRNRSATIDSGDSGIANIPVVLQDIATGVRLVVL
                     TDASGNYVFTNVPNGNYRIVEAFGTTGGVPTPGNFATAIVGPVPIAEMPPISSVTSPP
                     IGSTNLDGTTPNTLLITVAGSDITNQNILNGPVIYTPIENILDSCVSVSNINLITDAD
                     NGTFGFFPPGTPSNTGPEIEPYPNVTPDFTYVVPDPTKFTPLDGEYTVQNIMTNAMSN
                     VIGAWWRIADHTTGNETGRMMVVNGFNPGAVFFKSTVQVTPNTNYLFSTWILNLFKVT
                     GYPPPQLGVRIFDQNNNILYQATLGAQIPVNTNAPEWKEVGTVINSQNNNQLTVEFFS
                     EGESAIGNDYAIDDVSLREIAVPTFTPIKTSNTETANVGDIITYTVTLDNTCDSPLTN
                     VFFRDLIPNGLEFIPGTVTVDGVSVPGVDPNTGFPLPDIGGGTGVEVTFDVVVESIPN
                     PNPTNNIATIDYSYTPVEGGIPNDFSVDSNPVPVEVISADIEVTKLSEPTIVNPGEEL
                     IYTIKVVNNGPFPSENVVLTDDVPASIVNPEYSLDGGVTFQPWTGSLNIGTLEVGETR
                     VIIIRGIVNPSTVGIITNTAVVSSTTADPNLNNNTSTIETEVNLLADILVMKTAEPNS
                     AVPGTLLRYTIQVENLGPANAENVILNDDIPASIINPEYSLDGGASFQPWNGSLNIGT
                     LNSGISLTVLIQGTVSLNSSEYIVNTATVSSTTPDPDLSNNISTIITPVNPQAGISII
                     KVADEDVAVPGEEFVYTIEIFNEGPSNATNVVLTDDIPDVILNPEYSLDGGATFQPWT
                     GSLNIGTVAPGQLIRIIIKGLVSSTATGDITNTAEVSADVPEPVTDSSTVTTPIVPSA
                     DIEVIKTSNMDTAVPGETFSYTITVTNLGPSAAQSIVLTDDIPDVILNPEYSLDGGVT
                     FQPWNGNLSIGTLDAGEIRSIIIRGTVSQTAVGTIINTATISSPTPDPNPDNNTSTDE
                     TDISPLADISVIKGNEPVAIPGGRFIYGIEIANAGPSFTENVTLTDNIPASILNPEYS
                     IDNGVTFQPWNGSLNIGTLDAGEIRNIIIRGTVSQTAIGTIINTATVSSTTPDPNLNN
                     NTSTSEAEVSSSADISVVKRSNQIVVVPGDVLDYTIEVRNAGPSTTQNVTLTDNIPAS
                     ILSPEYSIDNGVTFQPWNGSLSIGTLDAGEIRNIIIRGIVSQTAIGTIINTATVSSTT
                     PDPNPDNNTSTSEIDISSSADISVIKLANKTEACVGEQIDFVIVVSNAGPENAQNVTL
                     IDNVSDKLKKAVFSLDRGVSFQPWTGSLNIGTLPAGTLRVILLRGIIKSTCLDRLTNI
                     AEITSTTPDSNLNNNISRVQVEIKQCCCNDCCCNNCSNCCCNDCGCKDCCCNCCKNDF
                     WC"
BASE COUNT        17316 a         4640 c         7447 g        13544 t
ORIGIN      
        1 atcagtctta catatatttc cgatagatta tattgataaa aaacactaaa attaaattaa
       61 taaaagtact tggagggatg gaaatgaaag aggaaaattt tattaatgtt gaatacgagg
      121 ataaacgttt ttcaattaat agtaaagaag ttttgtacat agaaaagcaa gagtatgaag
      181 taaagattta tactgaaagt ggtaattatg aagttggaga aaatgctcct tgtataagaa
      241 aactattgaa agaagaaaat tttttcaaat gcagtaatag ttatattgta aatctagaca
      301 agtgtgaatt ttatctcagc aataattgta tttttgtgaa taataatttt ataagaattt
      361 taggttcaga aagaaaaaag aaattaaaaa agaaattaga aaaattatat gattatgaag
      421 attaatattg ggaggctgta ttttatacag cctctttatt tattgattgt attattaata
      481 aattttaaat tatgataaaa tataaaacaa gtaacttatt tcagaataaa atacttttta
      541 aaagaaaggg acgagatatg ggagattata ataaaatgct tgaattaaag aataacttag
      601 gtatcagtga aagaaagtta aaatatcctt gtatctataa acatttcaaa gggaaatatt
      661 atgctacaat gggtcttagc aaggctattg atgatataga aaacatatgt gaaatatatg
      721 gtaaagaaaa tttaatccaa aacagaaata aatataaatt agttattaga catactgaaa
      781 gagaagaaga tatctatgtt tatagggatt tagatggaaa cttttatcat aaaaaagaag
      841 aagatactaa tgatttagtt ttatacaaga ccttatatga tgatacagga atatttgcaa
      901 gacctttgga tatgttttta gaaaaagtag atacagataa gtatgtcaat tcaattcaag
      961 aatacagatt tgaagaagta tataaataat ataagagaaa tatgtttata aatttagaaa
     1021 aattctttaa cagtacaata atttgcagaa atacaaatga gatttattgt aaataatatg
     1081 ttagattaga ttataaaata gaaacaaagt aaagtattat atgatataat taagttttga
     1141 gaagtgataa tttatattta ataaaaaata ggcatatatt aggaggacat atgggaaata
     1201 ctttttatat agtaagacat ggacaaacgg attggaatat attgggaaaa acacaaggtc
     1261 atggtaattc tgaccttacg cctcaaggta tagaacaggc aaaagaactt tctgaagata
     1321 ttggcaagta ttcaattgat tatattttta gtagcgacct tgggagagca atgcaaacag
     1381 ctcaaatttt aggagataag ctcaatattg aagttcaaaa aactgaggca cttagagaaa
     1441 tgggattcgg agtttgggaa ggccttttaa taaaagaaat tcaaaaagat tattcagata
     1501 tatatgcaac atggagaaat gaaccacact tagtaaatat accagaaggc gaaactctta
     1561 agattataaa ggaaagagta gatgctttta taaaggaact aaatgaaaaa tatgataata
     1621 aaaatataat tcttgttaca cattcaatta cattgagggt tatgttgttg tcatttttag
     1681 aatcaggtat ggaaaatata tatagaatta agcaagataa tactgcttta aatatagtag
     1741 aatttaaaga ttatgggcct gttatagtaa aaatgaatga tacaagtcat ataaaaaatc
     1801 atgtaaagat aaataattct gcactggagt aggaatcaat tataaggaga aatttatgag
     1861 taaagttata gtagttggtg gaggagcttc tggaatgatg gcagctttgt cagcttcaaa
     1921 aaacaataat gaagtaatat tagttgagag aaatggagaa ttaggaagaa aacttagggc
     1981 aactggtggc ggtagatgca attttaccaa taatagagag atagaagatt tttttgataa
     2041 agttgtcagt aataaaaaat ttctctatag tagtttttat acatttacaa ataaagacct
     2101 tatttcgtat tttgaaagta gaaatttgga atataagatt gaagaagaaa atgaccacaa
     2161 agtatacact aaaaatgata aatctataga agtaatagaa gtattaaata aagatttact
     2221 caatcacaat gtaaagataa tgtataataa gaaagttata gatattataa ctgaagaaat
     2281 tgctctaaaa gatgattcta ataaggacaa gtcaaagtat ctaataaaag ggattatttt
     2341 agataatgga gataaaatac taggagacaa ggttattata tcaactggag gagtgagtta
     2401 ttcaaagacg ggttcagatg gttcaatgta taagattctt aaaaagcatg gacatacatt
     2461 aaacaaacta tatcctgctt tagttccact tacaatagag gaaaaatgga ttaaagattt
     2521 acaaggaata tccatgaaga atgtggaaat atcttgtaag attaagaaaa ggaaaatatc
     2581 aaaatctgga gacatgctat ttgcccattt tgggataaca ggaccttgtg ttcttataat
     2641 gtcttcttat attaacaaga ttattgaaaa ggaaaaggta gaattaaata tagatttctt
     2701 accaaattta agtactgatg aaatctctag tataatcaga gcatttccaa ataaaaatgt
     2761 tctaaataat cttaagcaaa tactacctca aaatttctta aaagagattt tttctctatt
     2821 atctttagtt gataaaaagg caagtgattt gtctaaggca gatgaaatta gaattattga
     2881 gtatataaaa aatatgaagc taacttgtaa tgggactaca ggtataaaca ctggtatggt
     2941 tacttctggt ggtatttcag ttaaagaaat taattcttct actatggaat ctaaattagt
     3001 taagaactta ttttttacag gtgaagtaat tgatatagat gcagaaactg gtggatataa
     3061 tttacaaata gcattttcaa ctggatatct tgcgggtata agtgtataaa tataattttt
     3121 taataattaa atatgaataa atagaggtgt atatatgggt aatttagtta tagctgtaga
     3181 tggtccagca ggagctggaa aaagtacaat agccaagata gtagcaaaaa agctaaatat
     3241 aaattatata gatacaggtg ctatgtacag agcagttact tataagtgtt taaaaagtgg
     3301 tattgatgtc aataatgaaa aagaagttat tcaaatagct gaaaattcgg atatagattt
     3361 taaagataac aatatatatt tggacaaaga agttataaat gaagaaataa gaacaataga
     3421 agtaagcaat aatgtttcta atgtagcaaa aataaaagaa gtaagacagt tgatggttga
     3481 agttcaacga aaaataggaa tgaaaaattc agtaatacta gatggtagag atataggttc
     3541 atatgttttc ccagatgcag attacaaatt ctttttagta gctactccag aagaaagagg
     3601 aaatagacgc tataaagaac tttgtaataa aggatataat actactttag aagaagtaat
     3661 tgaggatata ataagacgag atgaaattga ttcaaataga gaatttgcac cattggtaaa
     3721 agctaatgat gcactagaaa tagatactac aggaaaaact atagaagaag ttgtagaaga
     3781 agttgtatct aaaataaatc tttagttttt tatgcatcat aatgaaaata aatgtagtgt
     3841 tgaagggaga taaacgtgaa tttttataga tttgtaataa atatttttaa gggtttttct
     3901 aaaatatttt ttaaatatga agttataggt gcagagaata ttccagatag aggaaatata
     3961 gtaatagcat caaatcataa atcgaatctt gaccctatat tcttggctgc tgccatagaa
     4021 aatagagaaa tagctgcaat tgcaaagaaa gaattgttta aagtaaaacc attgggattt
     4081 atattaaaaa aattgcatgt tatgcctata aatagagaaa aaccagatgt atctacaata
     4141 aaaactattt taaggtcagt tagagacggt tatgtattag gaatatttcc agagggtact
     4201 agaataaaag gagattcttt tggtaaggct aaggcaggtc tttctgtatt tacaataaaa
     4261 agtaaatcta aagttgttcc agtatcaata atatctaaat ataaactttt tagtaaagta
     4321 attgtatata ttggagaacc aatatcattt gaagaacatt ttaaggaaaa attgagtaat
     4381 gatgaccatg aaaggatatc acaagagatt ttagaagtga taaaacaaaa ttactttaaa
     4441 tattcaaaat aagggggtaa agttatgaac ataaaaatag caaaaaatgc tggcttttgt
     4501 tttggagtaa aaagagcaat gaaaatggca tgggatgaag ttgaaaaaaa tgattctggc
     4561 atatatgctt taggtcctct tattcataac aagcaagcag tagcaaaata tgaagaaaaa
     4621 ggtcttaaga ctgtgaatga aattgataca ataccaaatc atgaaaatat gataataagg
     4681 tctcatggag ttcctgaaaa tatatataag gaagccaaag ataaaaaatt aaaaattgtg
     4741 gatactacat gtccatttgt aaagaaaata catacagtag taagtgaata tcataataaa
     4801 ggctatgaaa taatagttat tggagatatg aagcatccag aagttatagg tataaatgga
     4861 tggtgtgaaa attcagctat aataataaag accttagaac aaatggaaaa tatggaattt
     4921 gataactcca aaagatattg tcttgttgca cagactacaa taaatccaga gttgtatata
     4981 agtatagtta ataaactatc agataaatta gaagaaatag tatttaatga tacaatttgt
     5041 tcagctacaa aaacaagaca agaatcagct aaagagttag ctaaagaagt tgattgtatg
     5101 atagttatag gaggtaaaca cagttcaaat actcaaaagt tagtaaaggt ttgtgaagac
     5161 ttagtaccaa cttttgcaat agagactaaa gatgaattgg atgtaaatac gcttaaaaaa
     5221 tataaaaatt tgggtattac agcaggggca tctacaccta attggataat agaagaagtt
     5281 gtaacattcc ttgaaaattt ataatttgat aggtaataaa aataggtgga cattgttata
     5341 atttatcata atatccacct ttgatttcat attacatgtg gtaaatagat aacctaatat
     5401 caaaaagtgt gtatcttaag atgaaaaact aagagtataa gatgcgcact ttttaatatt
     5461 agaaattcaa aagaaatatt gatattgatt atcaatagaa aatagaatat aatataattg
     5521 ttgcaaaatt agtctaggag gtaaattaat ggaaatgttg atatccgctt ctgaagaggc
     5581 gtttttacat gtaggttcta tgattggatt ttttattttg ttatttggat atattaatta
     5641 taaaactagt ggaaatttta ctaatatcat atcaaaaaac agaaaatttc aacccttaat
     5701 aggtgcttta attggagcta taccaggttg tggcggaagt ttggcaataa tgccattgta
     5761 tataaatgga aaattaagct ttggagcaat aattgcaagt ttaatagcta gtatgggaga
     5821 tgcagcattt gtacttattt catcaaatat taaaatgtat ttttttgtca ctatagttag
     5881 tacaattaca ggaataataa ctggacaatt agtggattac tttaaactag aagaaaaatt
     5941 agggttaaaa aaccgtagaa aatcagataa atatgatata agtaaaaata accctaaaga
     6001 aaataaagaa caacataatc atgatgaaat aattttagac actctagcta aatctcatgg
     6061 aaatacaaat agacttgcat ttataataac acatggaaag ggatataaaa tttatatagg
     6121 aattatagta atcggtttta tatttatgtc acttgctcac tctggactta atcttcctat
     6181 aattgagaag ttacattcat tggaagaagt aatagcagtg attggaatat tattttcaat
     6241 aatttatatg tggtgtttta aaaaggtatt taaaaattct aatcaaaaag aggaagaaaa
     6301 taaaaagatt tctttgcgag aaatgcttat ccattctgtt ggagaaatat catttgtaat
     6361 tacatggatt tttattgcat atcttattta cgatttgata atattaattt taggtggaga
     6421 tgaatactta gttaaattag tattatcaac aggtgtaata agtgtattta taggtgcagg
     6481 tcttggactt attccaggtt gtgggataca aattgtgctt atgtcatttt atttgaaggg
     6541 aactatacca cttggtgcag tgatagccaa ctctatttct caagatggag atgcactttt
     6601 cccactttta gcaatggata aaaaatcttc tttatgggct atgattatta ctactatacc
     6661 agcaatactt gtaggtatga tagtttatgc atttttaggt taaatataat tatgaataaa
     6721 gaagtattaa aaaaataata aagcacataa atttatttat aagaatagtg aagattaaat
     6781 ataaaaataa aaaattcaat atgaattaaa ttattgctta aatattaatg agaacatggg
     6841 agataatatt attcctcatg ttctctctat ttaattaaag gaattatgga acaaatttca
     6901 agtgatactt tctatcaaaa ctcatatata atatatatta ataaattaaa ctataatacg
     6961 taatacagtc agtatattga tataaaaaac ttaggaggag ttgtaaaaat gggtaattta
     7021 aaaagacagt gtgatgtttc aagtggaaga gaaaaagctg acattgtact aaaaaatggg
     7081 acaatcataa atgtatttac agaagagtta ataacaggag atgtagcaat agtaggagac
     7141 actattgttg gaattggcga ttacaagggc aatgtagaaa ttgattgtag taacaaatat
     7201 atatcacctg gctttattga tgcacatatg catattgaat ctacaatggt aatgccaatt
     7261 gaattatcga aaaaattatt aaaatcaggt acgacaacta tcatagccga cccacatgag
     7321 ttggtcaatg taaaaggagt tagtgcaata gattttttat tagaatcgac aaaagatata
     7381 ccacttaatg tatatattat ggtgccttca tccgtacctg caacaagttt tgaaactaat
     7441 ggagttggta aatttagtgc aaaagacatg gagagttatg taaataatcc tagaatttta
     7501 ggtttaggag aggtaatgtg ttttaatgat gttataaatt ctgaaaatga aatcttggat
     7561 aaactagagc tttttaaaaa taaagttgta gatggacatg cacctaatat aaatggtaaa
     7621 tcacttcaga catatgtatg tgcaggaata gaaaatgacc atgaatgtat aacttttgat
     7681 gaagtatatg aaaaattgag agcaggatta aaaattttaa taagagaagg aagcgcagca
     7741 aaaaatttaa agtctatagt aagtggtatg ctaaagcata acttgccaat tgaagaattt
     7801 atgttttgca cagatgataa gcacttagat gatatagaaa aacaaggtca cataagatgg
     7861 aatataaaat gtgcgattga tttaggtatg gaacctgtta gggctataaa agttgcaact
     7921 tataattctg caaaagcata tgggttaagg aaaattggag caataggtgc gggttataag
     7981 gcagatattg ttgtattgaa tgatttagac aaaatggaag tggatagtgt atataaagat
     8041 ggtaatttgg taaacgaaga gatgttttct aattacaatt atgagattaa agataaagaa
     8101 ttgcttaata cagtcaagtt taaatatatt aataaagaaa aaatacagtt aaaagtaagt
     8161 gaaaaaaatt atgtaatgga gattgtacct tatcaaattt tgacaaataa ggtatatgaa
     8221 tctttaccat gtgcagatgg atattttgtt ccaaataaag agtattcaaa actttgtgtt
     8281 gttgagagac atagaatgac tggaaatgta gcaattgctc cactaaaagg atttggcata
     8341 aaaaatggag caattgctac tactgtggcc catgattctc ataatattat agttgcaggg
     8401 gataatgatg atgatattct agtagctata aattacttaa aggaaataca aggtggttat
     8461 gtaattgtat caaatggaaa agttcttgca cacctaagtc ttcaagtagc tggattaatt
     8521 agtactttta cagctgaaga agtacaagaa attactgata atatgttgga gatagcaaga
     8581 aaaatggaag ttccagagta tgtagaccct tttattacac tttcttttat ggcacttcca
     8641 gttgttccac aaataagact tacagattta ggtctatttg atgttgagga atttaaattt
     8701 atatagatag tataaaagta ataataaatg aggctttctc aaaatagaga taagtctctt
     8761 tttattgttg aaatgatgaa aatatatttg atttcataca aaaaagagca tctcatgaac
     8821 taaaaatttt atttttagat atccttattt taattaatct atcatttaac attgttttaa
     8881 gcatagatat cttaataaaa ctattttcag tctattttaa catataaata catgaaaatt
     8941 atatatttat gaaactttat acataaaaaa taaaatattt tatttatata tagatttata
     9001 gggtaataat ataagcatag tataaaatta ttaataaaaa caaaaggaga gatatttatg
     9061 ttgagtatag gaacaaaagc accagaattt acactagaag ataaagatgg aaataaggta
     9121 agtatgtcag attttaaagg caaaaaagta gtagtatatt tttatcctaa agataataca
     9181 ccaggatgta cacgtcaagc ttgtgctttt agaaatgcat atgatggatt taaaaaggaa
     9241 gatatacaag ttattgggat aagtaaagat agtataaaat cacatcaaaa atttgcagaa
     9301 aagcatgaac ttccttttat tttactttct gaccctgact tagttgctat aaaagctttt
     9361 gatgtatgga aagagaaaaa aatgtatgga aaaactgcat tgggagttgt acgtgcgaca
     9421 tatattatag atgaaaatgg aattattgaa aaagtctttg aaaaagcaaa accagacaca
     9481 aatgcacaag agattcttga atatttggaa aaacaggagt aataagaatt tatgattata
     9541 atgttatcac cagctaaaaa tatgaagaat atagaagtat ttgatagaga tttgagtttg
     9601 ccttgcttta tagataacac aaaagaaata gtggaaaata taaagacatt tggtatagaa
     9661 gattttaaaa ataaaatgaa aattaatgaa aaattagctg tattaaataa aaatagattt
     9721 gaaagcatta aatttgatag attaggaaac cctgcaatct taacttatga tggaatacaa
     9781 tataaaaata tagaagcaga aaattttaca aggaaagatg aagagtttgc aaatagctgt
     9841 attcgaatca taagtggatt gtatggtgtt gtaaaaccat atgatagtat atatgaatat
     9901 agattagaaa tgcagacaaa attacaagta ggtgagttta agaatttata cgaatattgg
     9961 ggaaatcgta tatataaaga actaatcaaa gaaaaaacag ctatcgttaa tctttcatca
    10021 aatgaataca gcaaatccat agaaaaattt attaaagata gtgatacata tattacatgt
    10081 acttttaaag taaataaaaa tggcatattg aaagtggaat ctacacaagc aaagaaagct
    10141 agaggtatga tgacaaaata cattgtaaaa aataggataa gagatattga agaactgaaa
    10201 aagtttgatt tagaaggtta taagtataaa gaaaacttat ctaacaatag tgaatacata
    10261 tttgtaaaag agtagaagtt ttgttaaata ttaaatggca ttgttaaatt taggtaaaat
    10321 atacttagtg tgtattgaat tgaacttgat tttaaaatat aattattctt aaattaaaaa
    10381 aagaaaggag tggtcttcca aaatggaaaa tcacaaacag atgccttggc attcaagagc
    10441 aacgcatgaa attttagaaa gtctagattc atcagaggag gggctcaccg ataccgaggc
    10501 ggaaaaacgg cttaaagaga atggcttaaa tgaacttaga aaaaaaccac ctagaacaac
    10561 tttacaaatg ctttggagtc aaattacaga tgctatggtt atgatactaa taggagcagc
    10621 aatattatct ttgatatttg gcgaatttac agaagctttt gtaatactaa taattgtaac
    10681 agtaaatgca gttattggaa ttgttcaaga gaaaaaagca gaatcatcat tagaagcatt
    10741 aaaaaatatg aattcaccta cagctcgtgt tatgcgtgat ggtgaagaaa atgttattcc
    10801 agcaagtaat cttgtagtag gagatattgt ttttttagaa gatggagcta tggttccagc
    10861 agaccttcgt ttaatagaaa catcaagttt aaaaattcaa gaggcttctt taacaggaga
    10921 atctgttcca tcagaaaaag atgcagatac aatcttacct aaagaatgtg tattaggaga
    10981 ccgtagcaat atggcgtata catcttcaat agtcacatat ggtagaggtg taggtgttgt
    11041 agtagcaact ggtatggata cagaagtggg taacatagca catcttttag attcacaaga
    11101 tgattttgat actcctataa aacgtaaact taatactgtt ggaaagacat taagtgtcat
    11161 aggtattatt gtatgcgttg ttatatttgc aataggtgca ttttatcaga gacctctctt
    11221 gccaatgttt atgattgcaa tttcccttgc catatcaatt attccagagg gattacctgc
    11281 aacagctact attgtaatgg ctttaggcgt acagcgtatg gctaaaagaa atgctttaat
    11341 tagaaaatta cctgctgttg aaacattagg aggagctaca gtaatatgtt gtgataaaac
    11401 tggtacatta accttaaata aaatgactgt tacacatatt gctgtcaatg gagattttga
    11461 atctggaaaa gtgacatcaa tagatactgc atctgaaaaa catccattag tgtataaaga
    11521 gattgtttat gctggtgcac tttgtaatga tgcatgtatt aatccagata aaacagatga
    11581 aatattaggt gacccaacag agggcgcatt aatttttatg gccaaaaaat ttggaataga
    11641 tcaagaagct cttgaagaag aatatccacg tgtatttgaa cagccttttg attcagatag
    11701 aaaatgtatg acaactgttc ataatataga tgaaaagatt attgcttata ctaaaggagc
    11761 agtagacgaa attcttgacc tatgtactaa aatattaact tcaaaaggtg aaagaaacat
    11821 tactgaagtg gataaaaaga atatacacga attatgtctt aacatgtcta aagatgcatt
    11881 gcgtgtactt ggttttgcta agcgtgagat ttcatctata ccaaaagaag atagtgaaaa
    11941 tatagaatat gatttaacat ttataggtat ggttggtatg attgacccac caagaactga
    12001 ggtaattgat gcagtaagta cttgtaaaga agcaggtata agaaccataa tgataacagg
    12061 tgaccataaa gttactgcca caacaatcgc tcatgagtta ggaatatgga gtgaagaaaa
    12121 tactgtgata tctggtgatg aacttgataa tttgagtgat gatgaactag atgaagctgt
    12181 taaaaatact acagtatttg ctcgtgtatc cccatttgat aaacttagaa ttatacaatc
    12241 tctaaaaaga attggagaag taccagcaat gactggggat ggtgtaaatg actctcctgc
    12301 cttaaagtct gctgatattg gtatagccat gggtataagt ggtacagatg ttgcaaaaga
    12361 ttcttctgac atgattttaa tggacgatag ttttacaaca attgcttatg caataaaaga
    12421 aggtagacgt gtatatagaa acatacaaaa agttatacaa tttttgcttg ttggtaatat
    12481 agcagagata cttacgttgt ttgtagcaat attattaaat tgggatactc cgcttcttgc
    12541 tgttcatatt ctatgggtaa accttgcaac tgctacgctt ccagcccttg ctcttggagt
    12601 tgacccacca agcagaaata taatgaagca ccagccagtg aaatcaacca ctttgtttga
    12661 aaaaaatctt atacaaagag ttgttaccca aggtgtattt gtggcaataa tgactatttt
    12721 agcatataaa attggtctta atatagaaaa tcattctgta ggtcaaacaa tggcattttg
    12781 tgtattagca ttttcacaga tgttacgagc atttagtcag cgttcaaata cagattcaat
    12841 gtttaataga aataatggta aaaatccatt tcttttaatc tcatttttaa cttctgcatt
    12901 tttaatagca gtaatactgt ttgtacctgt ttttagaaat gcttttaact taacagtttt
    12961 aaataactta gagtggctta taacgattgt tttagccata atgtctgtaa ttcaagtaga
    13021 ggttgggaaa attattaaaa gaaaaaaatt aaaaaaatag ttgacaaaat taggaaaaat
    13081 atataagata taaaacatag aaaaattaaa taaatcttat ccagagaggt ggagggactg
    13141 gccctatgaa acccggcaac cagtatattt atatacattg gtgctaaatc ctgcggcgaa
    13201 agctgagaga tgagtataat taagcttata cagagcctga gttatatact caggctttat
    13261 ttattttaac tctcatctgg taaatagttt aatttttttt actaaaatct aagggggata
    13321 caagaatgta taataaagaa acaatatgtg tgcaaggaaa ttataaacca ggtaatggag
    13381 aaccaagagt actaccttta tatcaaagta caacttttaa atatagcagt atagaccaac
    13441 ttgctgaatt atttgattta aaagttgatg gacatatata ttcaagaata agcaatccta
    13501 ctattcaagc ttttgaagaa aaaataagtt tactagaggg tggagtatct tctgtagctg
    13561 tatcatcagg gcaatctgca aatatgttgg cagttttaaa tatatgtaaa tcaggagata
    13621 gtatactttg ttcttcaaaa gtatatggag gaacattcaa tttactagga cctagtctta
    13681 aaaaatttgg tatagattta atatcgtttg acttagattc aagtgaagat gagatagtag
    13741 aacttgcaaa ggaaaatact aaggttgtgt ttgcagaaac acttgcaaat ccaactcttg
    13801 aagtcataga ttttgaaaaa atagcaaatg tagctaagag aattaatgtt ccatttattg
    13861 ttgataattc attagcatct ccagtgcttt gtaacccttt aaagtatgga gcaaatatag
    13921 ttactcattc taccacaaaa tatttagatg ggcatgcttc aagtgttgga ggaattatag
    13981 tggatggtgg aaactttaac tgggataatg gaaaatttcc agaattagtt gagccagacc
    14041 caacatatca tggtataagc tatactcaaa aatttggaaa tgccgcatat gcaactaaag
    14101 caagagttca gttgcttaga gactatggaa attgtttaag cccattcaat gcgtatctta
    14161 ctaatttaaa tgttgaaaca ctacatctta gaatggagag acatagtgaa aatgcactta
    14221 aaatagctag atttttagaa aaacatgaaa atgtagattg gattaattac ccaggacttg
    14281 aagataacaa gtattatgag aatgccaaaa agtatttatc aagaggatgt agtggtgttt
    14341 tatcatttgg agtaagaggt gggttagaaa atgccaaaaa atttgtggaa aaattacaga
    14401 tagcatcttt ggttacacat gtttcagatg taagaacttg tgttatacat ccagcttcaa
    14461 ctactcatag acaattaaca gaagaacaat taattgcatc tggagtattg ccttcactaa
    14521 taagattatc tgttggaata gaaaatgtag aggatttaat agctgattta aatcaagctt
    14581 taaatttcta atattctaag agaaagagaa gtgaaaagat atggctttaa tactaccaaa
    14641 gggattacct gttattaata aattattaga tgaaggaata gatgtaattt ataaagaaga
    14701 ttttaaaaag gaattaaagt atgaagaaaa catagacact aagatagcta tactaaatct
    14761 aatgcctata aagatagata cagaattaga tttactaaga aggatagata aaacaggatt
    14821 caacgtgtct gtggaattta ttaaaatttc aacaagagaa agtaaaagaa gttgtaatga
    14881 atatgttaaa gaattttata aaacatttga tgaagccaaa ggagagtatt ttgatggctt
    14941 tataataaca ggagctccag ttgaacaaat ggagtttgaa gaagttgatt attggaatga
    15001 actagaagaa attatggatt attctaagag aaaaactaaa tctacattat atatatgttg
    15061 ggcagctcaa gcaagtcttt acaaatacta caatgtaaaa aaacttccac taagtcaaaa
    15121 atgttttgga gtatttaagc ataaggtaga taaagatagt aaaatagtag atggatttga
    15181 aaatgaattt tttgctccac attcaagaca tactactgta aatattgaag ctttgaaaga
    15241 gaataaagag ttgagcattg tgagtcattc taaagaagct ggtccctata taattacaaa
    15301 ttcaagagat gtgttcgtaa tgggtcatag cgagtatgac aaatacactc ttgataaaga
    15361 atataagagg gatataaata aaggagataa aatatctata cctcaaaatt actatattaa
    15421 tgatgaccct tcagaagagc caactgtaaa atggaaaaaa cattcagaat tgttgtttag
    15481 aaattggata aaaaactatt tgatacaata aattttaaga gtatataaat gttaactaaa
    15541 aaaatataga aatttatagg tataaagtta atcttaatga tactttatac cttatttttt
    15601 ttaaatttga ccttataata gtagttttat attttaagaa aatcacttta ggtgtatgta
    15661 gatagaggtg gctttaattt tatatatggt gcgataatgg gagactaaac ctttatagta
    15721 tcaataaatt tgtattttaa cttttaaaag agattaaaaa gggagaaatc agtgtaaaat
    15781 atatatatag attttttatt aaattttatt aaaaatatcc tgtataaaat taaatatcaa
    15841 taagataaca aaattccaat tgaagttaca atattgtaat tgacaataaa tacttaatac
    15901 tataatattt aatacattaa acattatagt gttaagtatt tatttacagt atgcacttca
    15961 gcctaaattt gaaataaagt attttcgtag ggagcgtttg tatggatgag atgagtttta
    16021 agaaagagct actagagttg actagagata taaatatgaa atttacaact ttattaagtg
    16081 atttttatca gccacttggt attacagcag tgcaagcttt gattttatct gagttatgtg
    16141 aacatggaga gaaaaaaata agcgatttag ggaagaactt aaacatgaca aatagtaatg
    16201 tatcagtaat ctgtcaaagg cttgaaaaaa atggcttttt aaatcgcata agagatatag
    16261 aagaccaacg aattgtaaaa gtaaaagtta caaataaatc attggatata caagaacata
    16321 tttcaagtag tatttttgat agttattttg aaaatatgac cagtgaaaaa ttgcaagata
    16381 tggaagatat aatagaaggt ttagagaaat taaataaact tttaacttac attgattgca
    16441 aataacataa aaataattta aaggagaata aaattatgga tgaacataaa ccccaaaaaa
    16501 ggtcagcact ctattattat acagttataa taatagtagt aatgttttta aatgctttaa
    16561 tatttccaag tttaatggat aaaaaaatgg ttgagattga ctatggaaag tttctcacaa
    16621 tgttggatac aggaaaggtt aaatctgttg agatagaaaa taatagaata gcaataaatc
    16681 catctagtag caaggataag aatatataca taactggtag aatggatgac ccagaattgg
    16741 tagatagact aaaaaatgca aaagtagaat ttactaaggt tattcctaag gaaaattcac
    16801 ctcttttaag tattttactt acatggataa tacctatagg tattcttatg ctatttggta
    16861 acttaatgat gaagtctatg caaaagcgaa tgggtggtaa tgctatgcaa tttggaaaaa
    16921 gcaacgccaa aatgtatgta tctgctcaaa gtggaaaaag atttaatgat gtagctggtc
    16981 aagatgaggc aaaagaagct ttaactgaaa tagtagattt cttgcacaat ccagaaaagt
    17041 ataaaaagat aggagcacaa atgcctaaag gagcactttt agtaggacct ccaggtacag
    17101 gaaaaacact ccttgcaaaa gctgtagcag gtgaagcaaa tgtaccattt ttctcaatat
    17161 ctggttctga gtttgttgag atgtttgtag gaatgggagc ttctaggatt cgtgatttat
    17221 ttaaacaagc aaaagaaaaa gctccatgta tagtgtttat agatgagatt gatactattg
    17281 gtaaaaagcg tgataatgga agtggattag gtggaaatga tgaacgtgaa caaactttaa
    17341 atcagttgtt aagtgagatg gatggttttg atggtggaat tggagtagta atacttgctg
    17401 ctacaaatag acctgacagt cttgacaaag cattacttcg tccaggaaga tttgatagac
    17461 gtataccagt tgaacttcca gaccttggag gacgtgaagc tatattaaag gtacatgctc
    17521 aaaatgtaaa tgtaagctca gatatagatt ataatgcaat tgcaaggtct acatcaggag
    17581 catcaggtgc agaacttgca aatattgtaa acgaagcagc acttttagca gttaagtctg
    17641 gcagagatat agtagaacaa caggattttg aagaatctgt tgaaactgta attgctgggt
    17701 atcaacgtaa gggagctgta atttcagata aggaaaagaa aattatagca tatcatgaaa
    17761 taggtcatgc acttgttgct gctatgcaaa aacattctgc acctgtccat aagattacta
    17821 taatacctag aacttcagga gcattgggat atactatgca agttgctgaa gatgagagtg
    17881 tacttatgtc taaagaagaa gcaattgata aaataactac ttttacaggt ggtcgtgctg
    17941 ctgaagaggt tatctttaac acttgtacat caggagcatc aaatgatata gaacaagcta
    18001 ctaaaattgc aagagctatg gttactcgcc ttggtatgag tgaagagttt gatatggtcg
    18061 ctcttgaaac tgtaagcaat caatatttag gaggagatac ttctcttgct tgttcttccg
    18121 acactgctgc taaaatagat gaagaggtat ttaaaatagt aaaggcttgt cacaaaaatg
    18181 caattgaaat cttagaaaat aatattgata aattgcatga acttgctaat tatttattag
    18241 aaaaagaaac tattacaggt gatgagttta tggaaatact taacttaaac taaaatgatt
    18301 atacacaaga taaaaatgcc tattgttagg catttttatt ttacaactaa attttttaaa
    18361 ttcatattta aatctttaca taatcttaat cattaaaaat acatcttaac tacaatttta
    18421 tatcggaatt gatattataa tagtaatgaa tggtgtaagg aggtttttta atggatagac
    18481 ctaatcctga tattctatta gaaaaaatta aaaatgaaga agaaaaacta agtagaggtc
    18541 aattaaaaat attctttggt tatgcagctg gagtaggaaa aacctactct atgttggaat
    18601 ctgcacaaaa tttaaaaaaa gtgggtgtgg atgtagtagt tggatatatt gaaccacaca
    18661 ctagaccaga aacattggct ttacttgatg gcttggaaat tcttcctgta aaggatatag
    18721 aatataaatc tataaaacta aaagaatttg atttagatgc tgctttagca agaaaaccag
    18781 aagttatatt agtagatgaa tttgcccatt ctaatgttgc tgggttaagg catacaaaaa
    18841 gatggcaaga tatagaagaa ttgctgttag caggcataaa tgtctacact actgtaaatg
    18901 tacaacattt agaaagtcta aatgacattg ttgagataat tacaaacgta tcagttaaag
    18961 agactatacc agataagttt ttggatacaa atacacagtt agaacttata gatgttgaac
    19021 ctgatgtact tcttgaaagg ttcaatgaag gtaagatata taagaaagaa caagctacta
    19081 gagcaaaaaa taattttttt ataaaagata acttggttgc acttagagaa atcgcactta
    19141 gaaaaacagc agagagagtt aataaagaag ttcaaatgac cagactatca aagggtgatg
    19201 taactgtaat acctacatca gatacacttc ttgcatgtat aagtccatct ccatcttcag
    19261 caaaagttat tagaactgca tccagaatat cagacagtac atttgcaaaa tggatagctt
    19321 tatatgttga aactccaaac acagcaagac ttccatttga tgaacaaaaa caactacaaa
    19381 ataacctaaa attagctaag aaattaggtg gagaaataat tgttttacat ggtgaaaata
    19441 taatagagca aatacttaga attgcaaaac tgagaaatgt aacaaaaatt gtaataggta
    19501 gaaatcattc aagtaataaa agatttagta aaagatttaa aaaagatata gttgacaaat
    19561 taattgatga agttgattat atagatatac atataattcc atataaattt gcctcagatg
    19621 ttaaatacaa acctaaaaag gataaatcat caataaaatc taaatttaaa attagcaaag
    19681 ttgattttat aaaacttata tttattactt tgatgataag tattttagca tatgcagtac
    19741 aaagcatggg atttataaga gaaaatatat tgttaatata tatgttgggt gtagttttag
    19801 tttctatgtg gactaaaggg tatagtacag gtataataag ttctgtattt aatatagttc
    19861 ttttaaatta tttttttaca gcaccattat atacattatc tatagcagat tcaaactata
    19921 tagtaacact ggttgtattc tcaatagtag gtataataac tagcactctt acgtctaaga
    19981 tacagcatga agcagaaact gctgctaaaa gagaagaaaa tacaaaaatg atatatcaaa
    20041 taattaaggg atttttaaga ttatcaaata aagatgatat agtaaacaaa ggtatagaac
    20101 ttttgtctct tagcttaagt agagatgtaa tttgttattt aaatgtagat aagcataata
    20161 aatcaaagct ttacaaaaaa aatactaata ataaggataa aaatgatttg gatagtgaag
    20221 atgaaaaagc tgttgcaagt tgggttttat ccaattcaac agtggcagga aatgacacgg
    20281 atacacttcc tggttcaaag ggatactata taccaattgt aggaatgaat ttaactttag
    20341 gagtagtggg aatatcatgt attgattcaa aattggatac agaagatata agcttaattg
    20401 aaacaataat tgctcaaatg gcaatagcgc ttgatagaga aatcttgtca gaagctaaag
    20461 aaaataccaa tcttgagatt gaaagggaaa gattaagaag taatctttta agagcagttt
    20521 cgcatgacct tagaactcca ctagcaggaa tatctggtgc agtaagtaca attataaaaa
    20581 acaagggtac tataggtcaa gatataatag atgaattact tagtggtgta tatgaagata
    20641 ctcagtggtt aataagactt gttgaaaatt tacttagtat gaccaagata gatgaaggga
    20701 aattggaagt taaaaaacat tctgaactgg ttgaggaaat tatatcagaa gcgttacaaa
    20761 aaataaaaaa aagaattgaa aatgcactta tagatattaa tataccagaa cagatattat
    20821 ttgttcctat ggatgcaaaa ttaatagaac aagttttaat taatttaata gataattctt
    20881 tgaaatattc aaaggaagat tgtaagatag agataaatgt atatgagaaa gatgattatg
    20941 tttggtttga agtatctgat aatggtcctg gtatatcaaa ggaacttaaa aagcatatct
    21001 ttgacagatt ttttactgga gaagaaggag ctaaagattc cagaaagggt gttggacttg
    21061 gattatcaat ttgtaaatct ataattcaag ctcataaagg tgaaattatg gtagaaaaca
    21121 ataaagataa gggttcaact tttaagttta gtttgcctaa ggaaaatgaa tagttttaaa
    21181 ttttaaaatt agttttggag gaagaaatga gtaaaaaact tatattgtta gtagaggatg
    21241 ataagacaat aagaaaattt atatctactg cacttttaac acaggattat gatgtcaagg
    21301 aggctataac tggaaaagaa ggtatatcta tagctgtctc atattctcca gatgttgttc
    21361 ttttagattt aggcttagag gatatggatg gaatagaggt aataaaagct atcagacaat
    21421 tttcaaatat accaataatt gtagtttcag ctagagagca agatagagac aaggtagaag
    21481 tatttgatgc aggggcagat gattacttaa caaaaccatt ctccatagta gagttattag
    21541 caagagtaag agtagcattt agacattcac aagtagaagc tcaacaaaaa gatgatgtta
    21601 aatctacgtt tgaagtagat aaattattga ttgattttga taaaagaaaa gttattgttg
    21661 atgatgttga agtccatttg acacctattg aatataatat tctttcatta cttgcaaagc
    21721 atcatggaaa agtgcttact cataatttta taataaaaga aatatggggt agtgttatag
    21781 ggaatgagac taagtcttta agggtcttta tggcaacgtt aagacgaaaa atagaaaaac
    21841 aacctgcaaa cccaagatat ataattacag aagttggtgt aggatacaga ttaaatgatg
    21901 aatagttgta atatattaat tattagatta tgtgcttatt aatatatatt aaaattatat
    21961 agtttagtta aaataagaat gaagtgtatg tgcttgttgt cagtttagca catgcatttt
    22021 attttttagc ttttttagta tcaataattt tttagtatca ataatatgaa atatgtttta
    22081 aaataagtat atagtgtaat ctgtaataaa aactttggtt aaataataaa tgtatttaac
    22141 acttacctta taataaattt aatataaata ttaaataata attattaaaa tagtgtaaaa
    22201 taattacagt aaggattata aaaaattttt agaatgtaaa ttgaaattta ggagtagatg
    22261 tatgtatata ctgaatttaa atacaagaga gactattgaa gattttagag ataaatttta
    22321 tgtagcagaa aattcttatc ttatattaag tgctccaaaa aatttaaaat tgcttaagga
    22381 aactttggat atagatgaaa taacttttaa tgattgtctt aaatttgatg aaataaccaa
    22441 acttgattta tttgataatt acgatttttt aagcctaaat acatttgaac taagagatgg
    22501 agaagctgtt atagaagagg taaatatgta tttatcagat aattttatat tggttgtagt
    22561 gaatgaagaa cactttttat ttgaatttgt aaaaaatatt attttgaaga actctcaact
    22621 tgaaaaaaat ccagttatta atctatttaa gataaactac ttgattctta gagaagttat
    22681 aaaaaatggt tttgagtctt tggaaaaagt tgaagagtta attcttcaaa tagaagatga
    22741 aatgatggac aacattaata agaatcatgt atctagaata agtgatgtaa gaggattaac
    22801 aagaattata gttaagaata ctagacctct tttgtatatt ggggatagaa tagttaagga
    22861 aaatataaga tatttaaaat attcaaatgt aaaaaaatat aatttagaaa attttcaagg
    22921 tatagatttt ggaattgaca aattatacaa tttcgcattg tcaacacgag agttagcaga
    22981 taaattatta gatatttatt cttccagagt aggtgagaaa acaaataact taattacaaa
    23041 attaaccttg ttaacagcca tatcagcacc acttacaatt ataactggta tatatggaat
    23101 gaactttaga tatatgccag aattaaactg gatttatgga tatccagcaa ctttattttt
    23161 tatgctatgt ataatttttg ttggaattat aatatttaaa ataaaaaaat tattgtaaat
    23221 tacagatgat gtttaattga ttttataaaa atacatcaat tgagaagctg atttaagtaa
    23281 ataaaaaaat attttaaatt gaaaatattt atagaaaata ttgacaatta tattttcttt
    23341 gttataatta ttaaacaaga agaataataa attataaaaa tggaggataa tactatgaaa
    23401 ggaatattaa aagaactaac agcaaaactt tatagctttt tttactttat gttctggggc
    23461 ttttatttta gcgctggcta tttcttttac aaaaatatat gtacttcctt tctggtgagg
    23521 ccttatttta gtgattttga gcataagtaa attttataaa aatggttatt ttatatattt
    23581 atataagatt tagtgcttga tagattattt tagagaactc attagtgagt tctctttttt
    23641 attttaaata taaaattata atattgggag gtagtaaaaa tgatagtagt attaaaaatg
    23701 ggagcagaca aaaatgaagt taaaaaatta attgaggcta ttgggagaga aggagtagaa
    23761 gttaatccca tagatggaac agaattaact gttttaggtt tagttggaga tactagtaaa
    23821 atagatgcca aaagaataga agcaaataag gtagttgaaa aagttatgca tgtggtagag
    23881 ccttttaaaa aggccaatag aaaatttcat ccagaacctt caatcataaa tgttaatgga
    23941 atggaaattg gttcaaagaa aattgctatg atagctgggc cttgttctgt tgaaacagaa
    24001 gaccaaatag tatctatagc taaagatgtg aaaaaatcag gtgcaggatt tttgagaggt
    24061 ggagcattca aaccaagaac atcaccatac gctttccaag gattgaaata tgatggattg
    24121 gatttattaa aaaaagcaaa agaaaaaaca ggacttccta tagttacaga aataatgtca
    24181 acacaagata tagatatatt tgaagaaaat gtagatgtaa ttcaagttgg agctagaaac
    24241 atgcaaaact ttgatttatt aaaagaatta ggtaaaacaa ataaaacaat acttttaaaa
    24301 agaggattat ctgctacaat tgaagagtgg ctaatgtcag cagagtatat aatggctgga
    24361 ggaaatgaaa atgtagttct ttgtgaaaga ggtataagaa cttttgaaac atatactaga
    24421 aatactttgg atttaagtgc aattttagct gtgaagaaac ttagtcattt accagttata
    24481 gttgacccaa gtcatgcagc aggtaaatca tggatggttg actctttatc taaggcagca
    24541 attgcagttg gagcagatgg tctaataata gaagttcata atgacccagc acatgcactt
    24601 tgtgatggaa aacaatcgat taagccaaat gaatatgatg aattgataag tgaattaaag
    24661 actatcgcat cagcagttgg tagagaaata taatctataa aaggatggtt aaacgtggaa
    24721 gaaaaactat tagtaaattt aaaagaaaat agctacaata tatttattaa aaaaaatata
    24781 ctaaagaata taggagaaga aataaaaaaa atatattttg gaaataagat ttttattgta
    24841 actgatgaaa atatagcaaa attatacttg gataaagtaa aaaataattt aagtgaatct
    24901 ggatttgaaa ttaaatcttt aatattaaaa tctggtgaag aaacaaaatc atttaatact
    24961 cttcctaaaa tatacgatag tttacttgac tttaagttaa ctagaaaaga tttgattatt
    25021 actttaggag gaggggtaat aggtgattta ggtggatttg cagcagcaac ttttttaaga
    25081 ggtataagtt ttattcaaat tccaacatct ttattagcac aagttgatag ttctgtaggt
    25141 ggaaaagttg gagttgacct tgagagaggc aaaaatttag tgggaagctt ttaccaacca
    25201 aaggctgtgt ttatcgaccc aaatgtatta ttatcacttc cagaaaaatt ctatagagat
    25261 ggaatggcag aagttataaa atatggatgt ataaaagaca aaactttttt cgataaactt
    25321 ttaagtttaa aaaatagaga agaagtaatg caacatatag aatacattat acataaatgt
    25381 tgctttatta aaaaaactgt agttgaagct gatgaaaaag actttggaga tagaatgctt
    25441 ctaaactttg gccatacatt aggtcatgct attgagaaat actacaattt tacgggttat
    25501 acccatggag aagctgttgc cataggaatg tataagataa ctttagaaag tgaaaagata
    25561 ggaattacaa aaaaagggac atcagaactt ataaaatcaa ttttaatgaa ttataatttg
    25621 ccttatgaga ttgaattaag agataataaa tctatagtag atgctatatc tcttgataaa
    25681 aaaaatctag gtgatacatt aaaaataata cttttaaaag atattggaga gagtattata
    25741 tataatacta cttctaaatt ttttcaggag gtaagataat gggaagtcta aaaatatatc
    25801 caagtaaatt atctggagat gtaaaaatac caccatcaaa aagtatggca catagggcag
    25861 ttatttgttc atctctaagc aatggaaaaa gtagaatttc taatatagat ttttctgatg
    25921 atataatagc tactataaga gcaatgacat cattaggagc tattatagaa aagaaagaag
    25981 atattttaga aatttcgggg attttttcta aagaaggtat tttaaataga gagaatcagt
    26041 tgaatcaacc taaattgaca atagattgta atgaatcagg ctctacattg agatttttag
    26101 tacctatatc tttagcattt gatggtataa aaaggtttat aggtagaggt aatcttggaa
    26161 aaagaccact tgatacttat tatgagatat ttgacagaca gaatataaaa tatagttaca
    26221 aagaaaatca gttagatttg attatatcag gtaagcttaa accagatgaa tttagagtaa
    26281 aaggaaatat aagttctcag tttatcacag gtctactgtt tatattgcct acgctagaga
    26341 gtgattcaaa gataataatt actactgagc tagaatctaa aggatattta gatttaactc
    26401 tttcaacgat aaaagatttt ggggtagaaa ttataaacaa taactataaa gaatttatta
    26461 taaaaggaaa tcaaacgtat aaagcgagag attataaagt agaaggagat tattctcaag
    26521 gagcatttta tttatcagca gatgctatag gagaagatat tagcatatta gaccttaaag
    26581 aagattctct tcaaggggat agtgaagtag ttgaaatttt atctaggatg ggaatggaaa
    26641 tattaagaga aggcaacaaa ataaaaggaa taacaaatgg tttaaatggt actttgatag
    26701 atgcatctca atgcccagat ataatacctg tattatctgt agtagcatcc ttaagtatag
    26761 ggaggactac aataattaat gctggtaggc ttagaattaa agaatgtgat agacttcatg
    26821 caataaatgt tgagttaagt aaacttggag caaatataga ggagaaagag gatagtttga
    26881 taatcgaagg agtaagcaag ttaaatggtg gagtagaggt gtggagtcac aaagaccata
    26941 gaattgctat gacacttgca attgcttctt gtagatgtga taaaccaata atattaaaag
    27001 attttgagtg tgtatcaaaa tcttatccac atttttttaa agattttaag atgttaggag
    27061 gtcgaattga tgagtggaat atggggaaat aatttaaaag tatcaatttt tggagaatct
    27121 catggaaatg ctataggtat aaatatagat ggtcttcctt cggggattga acttgacctt
    27181 gataatattg ataaagaaat gaagagaaga gcacctggaa aaaattctat atctacttca
    27241 agaaatgaaa gtgatatacc agaaattcta agtggatatt ttaatggaag aactacagga
    27301 acgccattat gtgcaatcat aagaaatagt gatactcgtt caaaagatta tggagagctt
    27361 aaaaatttaa tgagaccagg acatgcagat ttcacaggta atgtgagata ttctggattt
    27421 aatgactata gagggggagg tcatttttca ggtaggataa cagctccatt agtattttgt
    27481 ggggctatat gtaaacaaat tttatcacaa aaaggaatag agataggagc acacataaaa
    27541 aaaattaaaa atatagaaga tatgagtttt gattatgtaa atatttcaaa acaacagtta
    27601 tcaaatttgc aaactttgga actaccttta cttgatttat caaaggaaga agccatgaaa
    27661 aatacgatta tagatgcaaa aaatcaagga gattcagttg gtggtataat tgagtgtgca
    27721 gtagtaggta ttaatgtagg gcttggaaat ccattttttg actctgttga atctacttta
    27781 tcacatttat tgttttctgt tcctgctgta aaaggtgtag agtttggttt aggttttgaa
    27841 cttgcagata tgtatgggtc tcaaagtaat gatgaaatgt attatgaagg aaatcaagtt
    27901 aagagcaaaa caaataacaa tggaggaatt ataggaggga ttactactgg aatgccaata
    27961 attttcaaag tggcaattaa gccaactcca tcaattagca gacaacaaaa cacagttaat
    28021 ataaaagata aaaaggacga tattttatat attaaaggta gacatgaccc ttgtatagtt
    28081 caaagggcta tacctgtaat agaagcagta acagccattg gaatttttga tttgatgaaa
    28141 ggacgataat aatggaggat ttaacgagat atagaaatga gattgacaat atagataaag
    28201 agcttattca attatttgaa aagagaatga atacagttct tgaaattgcc agacataaaa
    28261 tgaaaaataa cactactata cttcaaaaag atagagaaga aaaagtacta agtagagctg
    28321 tagataattt agataataaa gcatattcac aagaaacggt acagtttttt aattctataa
    28381 tggaaattag tagaggatta caaaaaagat tgatagataa tgatggtgag cagaaaatcg
    28441 agtttagttt agattcatca aataagaaat ttgatttgtc aaatgtaaat agatataagt
    28501 ctttaaaaga tgaattaaat aaaaaaaata tcctagtagg gttttcagga aaatcaggtt
    28561 catttacaga agaagcacta aataaattct tcaacaaaaa aatatcaaaa aaacaattta
    28621 aagaatttga agatgttttc atagcactta aaaataaaga aataaactat ggaataatcc
    28681 ccatagaaaa ttcatctaca ggagctatct ctgaaactta tgaccttttg agaaagtacg
    28741 gtttttatat agttggagaa gaatgtataa aaatagacca aaatttaata gggataaaag
    28801 acacaaagct tgaagatata aaagaaatat attctcatcc acaaggtata ggacaatgta
    28861 gtgaattttt aaaacaaaat agtacatgga aattgatacc atttaataac acagcaacaa
    28921 gtgcagaact tgtaaggaaa cttcaagata aaacaaaagc agcaattgca agcaaaaaag
    28981 ctgcaagtat ttatggatta gaaataataa gtccttgtat aaatgatatt gcaaacaact
    29041 atacaagatt tgtagtaatc agtaatcaaa tacacattga agaagaatca aacaaaatga
    29101 gtgtagtatt ttctgttgaa catgaagcag gaaaacttta taaagtactt ggatactttg
    29161 ctaaaaataa tataaatatg acaaaaatag aatcaagacc tatgaaaaat gcctcatgga
    29221 gatatttctt ttatatagat tttgagtgtt ctatatacaa ttctaaagtg tacgatttat
    29281 tagaattgat agaacataat acagcatatt ttaaatttat gggagtatat aaaaataaaa
    29341 ctgaatagat aagataaatt tttatttaat ttataattat taggaggtgt aagtatgaat
    29401 tttttcggtc tagtaggtga aaaactctct cacagtgttt cacctcaaat ccacaagaga
    29461 gtattcgaga tattgaatat tgaaagtgct tataaaaact ttgaaatttc aaaagaagat
    29521 atatctaagc tagacggtgc tataaaatta ttaggaatac aaggagtaaa tgttactgta
    29581 ccatataagg agcgtattat gaaatatctt gattttatat caccagaggc aaaacgtata
    29641 ggagcagtta atacaatttt actcagagaa aatatgttat atggttacaa tacagattac
    29701 tttggtcttg atagtatgtt taaaatggct aatattgatg ttcaaggaaa agtagcagtt
    29761 atattaggaa ctggaggtgc ttctaaagct gctcttacat attttattga ttctggtata
    29821 gaaaagcttt atgtttcaac tagaaaaaag gatgataaaa aattattaaa tagtaaagct
    29881 atattaatag attatgaaga acttaaacat ataaaaggag atataatatt aaatgctaca
    29941 ccagtaggta tgtaccctaa tgtaggaatt tcaccagtgt caaaatctat tatacaaaat
    30001 tttgatatat taatagattt aatttacaat cctggagaaa cagagttttt aagaattggt
    30061 aatagtatgg gtaaaaaaac ttgtgatgga ttatatatgc tggtggggca agcaataaaa
    30121 tctcaggaaa tttggcaaga tactaaaata gataatagta ttttagatgt tatatataat
    30181 gaactaaaat tagaattttt gtaagggaga ttgttatgat aaataaaaca aaagaaaaat
    30241 tgatattaat aggtatgcca ggtagtggaa aaactacaat tggtaaactt ttggccaaag
    30301 aatataattg tagtttctgt gatatggatg attatataat tcaaatatct caaaaaagta
    30361 tagcagagtt gttttcagaa ggagaagata tctttaggaa ctatgagact caagcatgta
    30421 gagaactttc tataagtgat aaaacagtga tatctacagg tggaggtgta ataaaaaagg
    30481 atgttaatat ggaaatacta aaagaaacag gtataataat ttttattgat agacctatac
    30541 aaaagatttt ggaagatata aatattaatt caagaccatt attaaaaaac ggaaaagata
    30601 gattgtataa tctttacaat gagagaataa atctttataa aaaattttca gatatagaga
    30661 ttttaaatga taaatcatta aataatgctg tatataatat tacaaatgca gtcagtgaaa
    30721 attttaaatt tgactttaaa gaaaaataat ctagggggaa gtaaaaataa tgaatattgt
    30781 tattgtagga ctaggagtta taggaggctc ttttgctaaa gcattaaaaa aagctggata
    30841 tgaaaatgta tttggagtag atgtagattt agaaacttta aaaaaagcag aaaaatcaaa
    30901 aatcataaaa aaaggatgta ctacaggtaa agagttattt aaaaaagctg atttaattat
    30961 actatctata tatcctagat tagttgtaga ttttctaaat aataataaaa acttttttaa
    31021 aaaagggact ataattactg atactacagg aataaaagaa acacttatca atgatgtgtt
    31081 gcaaattatt ccagatgata tagattttat atttggacat ccaatggcag gtagggaaaa
    31141 aaagggtatt gattttgcaa gtgaacaagt ttttaatggc gcaaattata taattactcc
    31201 aactggcaga aacaacataa aaaatttaga gttagttgaa aatttaattt tagagattgg
    31261 atttaaaaga gtaaaaaagt taacttcaca aaaacatgat gagattatag cttttacttc
    31321 tcagttacct catgttatgg cagttgctct tataaatagt gatgaagaag gtagagatac
    31381 gggtaaattt attggagata gttatagaga tttaactaga attgcaaata tgaatgaaga
    31441 cttatggagt gaactttttt taggaaatag agataattta ctaaaagtta tagaaaactt
    31501 tgaatcagaa gtaaatttag taaaagaagc tatatttaac aatgataaaa ataaattaat
    31561 agagtatttt aaaaaatcat caataagaag agaagcttta gaaaaataaa tattaatatt
    31621 taagctatat atagatgggt ataaatataa gcgatagtgt atttaattgt attaataaat
    31681 atggattcaa tataattaaa tatgctattg atatatttgt acccttaact attgttatct
    31741 tttaaatgat aatgatattt atttaaatac tctttattaa caatttataa aacttaattg
    31801 taaaaaatac ttattaatag taaaataaag tgaatcaatt atattataat tgctaaagag
    31861 agtgaggtgt agctatttga aaaaaaatag attaatagca aagaatatat caatagcatt
    31921 tatagtacta ttctttttta gtgtatttac atttttttat gtaggtaata ttaatagagt
    31981 gttagaatat gaaacaaatg acataataac agttacaatt gctggatgga ttatactttc
    32041 atttttattt ttaggtatta taatttacat attatattca aaagcaaata gtcaaaaaac
    32101 tatagaaaaa gtagcatata cggattttgt aacaggttat tccaactgga gaaagtttga
    32161 attagatgtt acaaatttat taaagaaaac atcacaaaat aataaatatg caatggtcat
    32221 attcgatatt gataaattta aagcaattaa tgatatatat ggtcataaaa agggaaattt
    32281 aatattaaaa gatattgcag atactttaaa tgaattgact aatatcaatg aaacttttgc
    32341 tcgtgtaagt gctgatagtt ttaatatatt attaacatat aacaaaaaag aggatataat
    32401 aaatattatc aaaaagatta tggcaaataa tgaacttgta aacttatctt ttggaattta
    32461 tgaaatcaaa gataaggatt tatctgtaag tgtatatagc gatagagctt cacttgcaaa
    32521 atcatcaata aaaaataata gtgatgtaaa ttttgcattt tttaatgata aattaagaga
    32581 gaaattatta cttgaagata agatagaaaa agaaatggaa tatgctcttg aaagtgggca
    32641 attcgtaatg tatttacaac caaaatacaa tattaaatta gataaatttt gtggaagtga
    32701 agccctagtc agatggcaat atacagaaaa agaggtcata tatccaggtg attttattcc
    32761 tatatttgaa aaaaatggat ttattagaaa gattgatatg tacatattag aacaagcttg
    32821 taaagaaatc cggtctttat ttgataaagg aatttcacct ttacctatat ctgtaaactt
    32881 ctcaagagtt gattttttta aaaaagattt tattgaaaac atagtaaata tatgtgatag
    32941 atataaaata ccatatagtt taatagaaat tgaaattact gaatctagta tgtttggaga
    33001 tactgatact ctatttaatg ttagtagaaa cctacaggat attggcttta tagttgcaat
    33061 ggatgatttt ggctcgggat attcttctgt aaatatgctt aaaaatatac cattaaatgt
    33121 aataaaatta gatagaggat tttttgttga tgataaagat gttgataaga gtcaaattgt
    33181 tataaaaagc atagtttctc tcattaagca attaggaata agggttgttg ctgaaggaat
    33241 tgaaacaaga agtcaaatag aaatgttaaa aaaagcaaat tgtgatattg ttcaaggata
    33301 ttatttttca aaaccattac caattaaaga atttgaaaaa ttagtctata aaatatagtc
    33361 agcgagtctt aaatgggagg tggtgattaa gtgataagag caaaatcgtt aaaaaatgta
    33421 ctgagtattg ttttaatatt tttatttaca ataatttctt tttctgattt tgcatttaaa
    33481 actaatgtcc aggaagaaga aaatagtaaa attaatttaa gggaaatatc cctacaaagt
    33541 tccaatgcta taaaaataaa attagatagt tctctatcct ttattaaaag tgtggcaaat
    33601 atggtttctt attttaatac tatagataac tcaaaaatag ttccattatt agctaatata
    33661 tcaaaagaat ctgactttca aagaatctct attgtatctc ctgatggaat aagtcatacc
    33721 agtgatggca aaattatcaa tgtgtcaaag tatcagtatt ttaagaaagc tattaaagga
    33781 gaaagtaata tatctgaagt tgtgaaatct ccaattgatg gaaaagatac ttttgttata
    33841 gctactcctg tatttaataa gaataacaaa ataattggtg ttttatacgg ttcttactac
    33901 aatgataaat tagctgaatt tatagatata acaagtttta atagtgaagg gtacatagat
    33961 atatttgaat ctagtggtca atttgtttta aaatcttcac atacaaacaa actgattaag
    34021 tcaagtagta acatatatga tatatttaaa aaagcttctt ttgatgatgg ttatagctat
    34081 aaaaaaatat atgaagatac aaaaaataac aagagtggct ttacctcata tgaatacaaa
    34141 ggagaaaatc gttatgctac ttatacaccc attggtgtaa atgactggta tgtaatttct
    34201 gtgataccac aatatactgt aagaagaaac attgataaaa taaatcaatt agcattttct
    34261 cttattttca aggtattctt attgtttatt atgcttataa tatatattat ttataaaaac
    34321 aataaatctc agaaagatat actaaaagct aacaaagaaa tctcatctat tacaaatagc
    34381 attcctggag gagtacaaaa gtgtaccctg ggtgaaacat gcaatattaa ttttttaagt
    34441 gatggattta tagagttgtt tggttataca agagaagaaa taaaaacatt gtttaataat
    34501 gatttttata gtttaataca taaagatgat gttgaaagaa taaaaaaaga aatttttaaa
    34561 caactttaca aaaataaaac tattgaatta gaatatagga ttataacaaa aaatggtaat
    34621 acagtatggg ttttagataa aggggagctt ataacagaac ctgatggaaa agaatatttt
    34681 tgttgtgtaa ctgtagatat tactagaaca aaacaattag aacaagagat ggaacaaaaa
    34741 aatctagaac ttgaaatgat atcagaaaat gttttaggtg gtataattat aacagaattt
    34801 aatgatgatt ttactataaa atacgctaac tctggttatc tttcaatgat tggatataca
    34861 cgtgaacaat tagaaaatga acttaaatac aaagcttgta atcttgtttt ttatgaggat
    34921 aaaaagaagg ctcttgaaag tatacaacat caattaaaca caaaaggaat agctgtatat
    34981 caacatagaa taagaagaag aaatggtaat attatttggg tttctataaa aggaaggctt
    35041 attgttgatg atgatggtat tgaaaaaggt atttggattc taaatgatat aacagattta
    35101 aaaaatgcag aacaaaaact taaaataaat gaagaaagat ttagaattgc attaaagcaa
    35161 acatcaaaca ctatatttga gtatgatata aaaacaaagt cacttttaaa tactagtaaa
    35221 gagcttgata aatataatat ttataaaatt actaaaaacg ttccatattc tctagtagaa
    35281 tcaggagtta ttcataaaga ttttagtgat gattttataa acatgtatga aaatgtaata
    35341 aatggagcaa aaaaagcaag ttgtgtagtt aagatgaaac ttccagatga aaattatata
    35401 tggaataaag ttaccttgac tactattttt gatgaagatg gtaatcctgt aagagcaatt
    35461 ggtatacagg aagatataag caaacaaaag gaagcagaga taagatacaa tcaagaaggt
    35521 aagtatcatt cagctatatt gtcggaagca atgataactt atgaaataaa tgtatcaaag
    35581 gatactttta tcaaaggaaa tgaaagttgg caaaaaccat ttggaattaa gcctgacaat
    35641 aactattctc aaatggtaaa aactatagca aatagtattg tacataaaga caataaagaa
    35701 acatttttaa atacattttt atgtgaaaac ttattggatg catataaaaa taatgtgact
    35761 gaaataaaat tagaatatcg aagaatgaat caagaaaata aaatgatttg ggtcatttgt
    35821 acaatgcact taataaaaga ttctattacg aacgatataa aagcacttgc ttatgttaaa
    35881 gatattgaca agcaaaaaaa tgaagaaatt agattaaaat taaaagctga aagagatact
    35941 cttacaggat tatataataa aggtactaca gaaaaattga ttaatgattt cttgaactct
    36001 gaggaagcaa gtttaggaat gcatgcattt ttaattgttg atatagataa ttttaaatct
    36061 gtgaatgata atttaggaca tgtatttgga gataaagtat tatttgaagt ttctaaaaac
    36121 ctaaaaccta tatttagaaa agatgatata gtaggtagaa ttggcggaga tgaatttata
    36181 gtattcttaa aaaatattca gtcttttgag aatatcaaaa agaaagcaga aaaaatatgc
    36241 gatatattta gaaattctta tacagaaaat aaaaagacat ataaaatatc tggaacagtt
    36301 ggaatttcat ttgtaccaga acatggaact gtatttgaag aactttataa aaaagcagac
    36361 atagcacttt attatgcaaa gagcaaagga aaagataagt atgcacttta taatgattgt
    36421 atctaccaaa atgaacttga aaataatata agtgataata atataaaatt agcagataaa
    36481 tgtgagaaat ccaaaccagt acttaaagaa attcttgatt ctattgataa ttatatctat
    36541 atagtgaatc caaatactta tgaacttctt tttatcaata ataaggtgtc tcgtttggat
    36601 ttagagataa aattaggaga aacctgttat aaatcactat taaaatctga tagaccatgt
    36661 aataattgcc ctcttaacgg attagaagaa aataagcatt caaaattcaa aatagagaca
    36721 aatacatttg gtaaaaatat cagtatagca agttggatta attgcataga tggagaatac
    36781 aactgtctta tagagtgtat agattcttct ttatacaaaa ataaataaaa aaggactatg
    36841 aagatatgtt aaatagtata actttgatac ttggtataat atttacaatt tactattttt
    36901 atctcaaaat agtttttgga ggaatttcat ttagtgagat tttcttagtt gtaggaattg
    36961 tactaattat ctatcaaata tttaagaaaa aaattaaaga aaagaaggtt ttttataggg
    37021 tgttaaaaat aataatcagc atttttttaa tagtatttgt agttactgag agtctaatta
    37081 ttttttatcc caaaaatagt ttagaatcaa aaagtgatta tctcttaatt ttaggagctt
    37141 ctgtaaaaaa gactacacca agtacaaccc tgaagggtag gttagacact gcattgaaat
    37201 acctaaaaat taatgataat tgttatgtgg tagtatctgg tggtaaagga agtggagaaa
    37261 aaataactga ggcaaaagct atgaaagatt atcttataaa aaatggtata gataaaaata
    37321 ggataataga agaggataaa tccacgaata cttatgagaa ttttaaatat tcaaaattga
    37381 agatagaaga acatagtcaa ggaaaactaa gcgatttaaa agtaaaaata gtaacaacag
    37441 attttcatgt tctcagaagt aaaatattag catatagaaa tggatataaa aatacgtctt
    37501 tttatgctag taaatcaaaa ctttcatttg taccaactta ctatacaaga gaattttttg
    37561 cattatggaa aacaatcatt tttgatagat aataaataaa aagactagat ataaactcat
    37621 atctagtctt ttctattccc ttaattctaa tccattttcc aactttactt gttgtagaaa
    37681 tttcaacatt gggatttaca agtaattgct tataagaagt tttatatttt acgattccaa
    37741 aatataattt tccttcataa tccattataa atccgaatgg tcttactctt ggtttattat
    37801 cttcaactgt agcaaaatag aatgttgagt tttctttaaa aaaattcatt attttttcat
    37861 gattaaatcc tctttgtatc ttatactaat ataatgaata taaataaaat attcataata
    37921 ctaatataaa tcgatataaa aacaattaca atattatatt gattattcaa aattatatat
    37981 aaaattcaga aaaaaatttt agtttacata ataaaaataa agtcaactaa aattattgat
    38041 tttagattaa agtaccggat taagcattta agtagatttt aagcttgatt tgattagaaa
    38101 ggtacaaact atcaccgaaa aaaattaaac ccatttaaaa agcaatataa aagcttgtta
    38161 tttttgagaa aaatagaccc tctaaactca attagattaa aaataaaata cagaaaatta
    38221 tatctctaaa tatcttaaat aattaagttt aaattttacg atattttgtt tgatgattta
    38281 taatataaaa gcatactctt aatcttcaaa atttaaaaag agtaaaaaat aacaaaaaaa
    38341 tcactgacat ttcactgaca aattgtaatt ttgttattat aaatacattg aaaatacttg
    38401 attattgaaa aatggcataa aataatacat tttatgccat ttgctattat ttgatagttt
    38461 ttaacttatg acataagata ttttttaaca tatacaataa aatataaaaa aattgatatt
    38521 gcaaataaaa aaaaatacat attagatgtt atagaaaaaa agcgcactta taggcttaaa
    38581 atgtcacata aaagagtttt aaagaataat atattatgaa cacaaatttt gtaatcacaa
    38641 aggagtgata atatggcaac agtatcagga caaatagttt ttgatagaaa tagaagtgct
    38701 accattgatt ctggagactc aggaatagcc aatataccag ttgtattaca agatatagca
    38761 actggagtta gacttgtggt tctcacagat gcatcaggaa attatgtttt tactaatgtt
    38821 ccaaatggta actatagaat tgtagaagct tttggaacta caggaggagt accaacacca
    38881 ggaaattttg caacagcgat agtaggtcca gttccaattg cagaaatgcc acctattagt
    38941 tctgtgacaa gtcctcctat tggttcaaca aacttagatg gtacaacacc taacacacta
    39001 ttaataacag tagcaggttc agatataaca aatcaaaata tattaaatgg gcctgtgatt
    39061 tatacaccta tagagaatat attggattct tgcgtatctg tatctaatat aaaccttatt
    39121 acagatgcag ataacggaac attcggtttt tttccaccag gtacaccaag taatacagga
    39181 cctgaaatag aaccttaccc aaatgtgacg ccagatttta cgtatgttgt accagaccca
    39241 actaagttta cacctttaga tggagaatat acagtacaaa atattatgac aaatgcaatg
    39301 agtaatgtta taggagcttg gtggcgtatt gctgaccata ctacaggaaa tgaaacagga
    39361 agaatgatgg tggtaaatgg ttttaatcct ggagctgtat tttttaaatc aacagtacaa
    39421 gttacaccta acactaatta tttatttagc acttggattt taaacctttt taaggtaaca
    39481 ggatatccac caccacagct aggtgtaaga atatttgacc aaaataataa tatactatat
    39541 caagcaacat taggagctca aattccagtt aatacaaacg caccagaatg gaaagaagta
    39601 ggtactgtga ttaattctca aaataataat caacttacag tagaattttt tagtgaagga
    39661 gaaagcgcca ttggaaatga ctatgctata gatgatgttt ctttaagaga aatagctgtt
    39721 ccaactttta ctccaataaa aacaagtaac acagaaactg ctaatgtagg tgatataatc
    39781 acatatacag ttacattaga taatacttgt gatagccctt taactaatgt attttttagg
    39841 gatttaattc caaatggttt agagtttata cctggaactg taacggttga tggagtatct
    39901 gtaccaggag tagaccccaa tacaggtttc ccacttccag atattggagg aggaacaggg
    39961 gttgaagtaa cttttgatgt tgtggttgaa agtattccta acccaaatcc tactaataat
    40021 atagctacta tagattactc ctatacacct gtagaaggcg gtataccaaa tgatttttca
    40081 gtagattcta atccagttcc tgttgaagta atctcagcag atattgaagt tacaaaatta
    40141 tctgaaccta ctatagtgaa tccaggagag gaattaatat acactataaa agtagtaaat
    40201 aatggaccat tcccatctga aaatgtggtt ttaacagatg atgtaccagc ttctattgta
    40261 aatccagagt attcattaga tggaggagta acttttcaac catggactgg aagtttaaat
    40321 atagggacat tagaagtagg agagacaaga gttattataa ttaggggtat tgtaaatcca
    40381 tcaacagtag gaattataac aaatacagct gtggtatctt caactacagc agacccaaac
    40441 cttaataata atacatctac aatagagaca gaagtgaatt tattagcaga tattttagta
    40501 atgaaaacag cagaacctaa ttcagctgtt ccaggtactt tattgagata tactattcaa
    40561 gtagaaaact taggaccagc aaatgctgaa aatgtaatat taaatgatga tattccagct
    40621 tctattataa atccagaata ttcattggat ggaggagcaa gttttcaacc atggaatgga
    40681 agtcttaata taggaacttt aaactctgga atttcattaa cagttttaat tcaaggaaca
    40741 gttagtttaa attcttcaga atatatagta aatacagcaa cagtttcttc aactacacct
    40801 gacccagatt taagcaacaa tatatctacc attattacac cagttaaccc acaagcaggt
    40861 atttctatta taaaagtagc tgacgaggat gtagctgttc caggagaaga atttgtatat
    40921 acaattgaaa tttttaatga aggaccatct aatgctacga atgtagtttt aacagatgat
    40981 ataccagatg ttattttaaa tccagaatat tcattggatg gaggagcaac tttccaacca
    41041 tggactggaa gtcttaatat aggtacagtt gcaccagggc aattaataag aattatcata
    41101 aagggattag taagttcaac tgctacagga gatattacta atacagcaga agtaagtgca
    41161 gatgtaccag aaccagttac ggattcatca acagtgacaa ctcctatagt tccatcagca
    41221 gatatagaag taataaaaac tagcaatatg gatacagcag ttccaggaga aactttcagt
    41281 tatactataa cagttacaaa tttaggacca tctgctgcac aaagtatcgt tttgacagat
    41341 gatataccag atgttatttt aaatccagag tattcattgg atggaggagt aactttccaa
    41401 ccatggaatg gaaatcttag tataggcact ttggatgctg gagaaataag aagtattata
    41461 ataagaggaa cagtgagcca gacagcagta ggtacaatta taaatacagc aacaataagt
    41521 tcacctacac ctgacccaaa tccagataat aatacttcaa cagatgaaac agatataagt
    41581 ccattagcag atatttctgt gataaaaggc aacgaaccag ttgctatacc agggggaaga
    41641 tttatttatg gaattgaaat tgcaaatgca ggaccatctt ttacagagaa cgtaacttta
    41701 acagataata taccagcttc tattttaaat ccagagtact caatagataa tggagtgact
    41761 ttccaaccat ggaatggaag ccttaatata ggtactttag atgctggaga gataagaaat
    41821 atcataataa ggggaacagt aagtcaaaca gcaataggca caattataaa tacagcaaca
    41881 gtaagttcaa ctacacctga cccaaatcta aataacaata cttcaacatc agaagcagag
    41941 gtaagttcat cagcagatat ttctgtagta aaacgaagca atcagattgt tgttgtacca
    42001 ggagatgtac tagactatac aattgaggtg agaaatgcag gaccgtctac tactcagaac
    42061 gtaactttaa cagataatat accagcttct attttaagtc cagaatattc aatagataat
    42121 ggagtgactt ttcaaccatg gaatggaagt cttagtatag gcactttaga tgctggagag
    42181 ataagaaata ttataataag gggaatagta agtcaaacag caataggtac aattataaat
    42241 acagcaacag taagttcaac tacacctgac ccaaatccag ataataatac ttcaacatca
    42301 gaaatagata taagttcatc agcagatatt tctgtaataa aattagcaaa taaaacagaa
    42361 gcatgtgtag gagagcaaat agattttgta atagtagtat caaatgcagg accagaaaat
    42421 gctcaaaatg ttactttaat agacaatgtt tcagataagc ttaagaaagc agtattttca
    42481 cttgatagag gtgtaagttt ccaaccatgg actggaagtc ttaatatagg tacactacca
    42541 gctggaactt taagagttat tctattaaga ggaattataa aatcaacatg tcttgataga
    42601 ttaacaaata ttgcagaaat tacttcaaca acaccagatt caaaccttaa caataatata
    42661 tcaagagtgc aagtagaaat aaaacaatgt tgttgtaatg attgctgttg taacaactgt
    42721 agtaattgtt gttgcaatga ttgtggttgt aaagattgtt gctgtaattg ttgtaaaaat
    42781 gacttttggt gttgatttta taaaataatt ttgtatacct taaattaaac tgaaataaaa
    42841 aataaattca catatgagta aaatatttta taaatattaa taaattttct atctttgata
    42901 tggaccacat tcgtaatact agttattaaa tgaagtggtc cttttta
//
LOCUS       DAMKNB010000030        41584 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.031, whole genome shotgun sequence.
ACCESSION   DAMKNB010000030 DAMKNB010000000
VERSION     DAMKNB010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 41584)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 41584)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..41584
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.031"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            239..1669
                     /locus_tag="PC494_001759"
     CDS             239..1669
                     /locus_tag="PC494_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4116 domain-containing protein"
                     /protein_id="HDF3912261.1"
                     /translation="MDIKNKIKSIFLPEKNDYLDDEEFEYDIENNEEDLKEDNKVHLN
                     DLSRVKYDYRELKDIENQTEEICLLAVKQDGTIIEFVKDKTYKVCMEAVKQTYKSLKY
                     ITNQNEDICIEAVKQNYRALYYINNKTENVLIEAIKNASTYDVMEVFKFVEEQTEDVC
                     LAFIERASKNDVAEILKGIKEQTPAICLEAVKKDGKSLAYVKEQSNSICLEAVKENYS
                     ALSCVKEQTEEICIEAVKQNDFALYYVNEQTEKICMEAVKRSYMALQYVNKQTEEICL
                     EAVRIDGRALQYVKEQTEEICLESVRQNGKVLQYVKKQTENICIEAVRGSFEELEIKE
                     ILSYVKIPTERIFVEAVKQNGKILKYVENQTELICLEAVRENYNALAYVKEQTEKICL
                     EAVNQSYEALKYVKEQTEEVCLKAVKQDYRMLKYVNNQTEKICLEAVKQNYRALEFVD
                     NQTEKVCLEAVKQNRKALQYVKQKQS"
     gene            2037..2615
                     /locus_tag="PC494_001760"
     CDS             2037..2615
                     /locus_tag="PC494_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory gene regulator B family protein"
                     /protein_id="HDF3912262.1"
                     /translation="MFKRYAEKMTSVLICNNMIDNNESKVYSYGFEILIAFIVNITTM
                     LFIGFLFGKFTYVLFFLMCYCPIRQFSGGYHADNYFRCLLTFIFIILSTILIIENINI
                     DLFKNIIMIIASVSWVGICVLCPIEHRSNPISDREKLVYKKTAIFISTVVLLITILSL
                     SLSIFVDYFTYSAFAMFWIFVMLVLGKLKAKV"
     gene            2645..2791
                     /locus_tag="PC494_001761"
     CDS             2645..2791
                     /locus_tag="PC494_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic lactone autoinducer peptide"
                     /protein_id="HDF3912263.1"
                     /translation="MKKFIVRFMKFASSLALSTAILSANSTCPWIIHQPKVPKEISNL
                     KKTN"
     gene            3096..4475
                     /gene="scfB"
                     /locus_tag="PC494_001762"
     CDS             3096..4475
                     /gene="scfB"
                     /locus_tag="PC494_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioether cross-link-forming SCIFF peptide
                     maturase"
                     /protein_id="HDF3912264.1"
                     /translation="MSMIHKFSMNGYNIVLDVNGGAVHVLDDVAYDLLDFYKEKSKEE
                     ILEILKSKYQEEKINEAYEEILNLEKEGLLYTEDTYQYHPSFVHREPVVKALCLNVAH
                     DCNLKCKYCFAAQGDFGGEKELMSFEVGKAAIDYLIANSGSRKNLEIDFFGGEPLMNF
                     EVVKQLVDYGRSVEKDYNKNIRFTITTNGVLLNDEIIDYINENMHNVVLSLDGRKEVN
                     DNMRPTLNDKGSYDITLPRFKKLVEKRAKDKYYYIRGTFTRDNLDFSKDVMHFADLGF
                     KLTSVEPVVGDESNPYALREEDLPKIFEEYEKFAVEYADRQLQGDGFKFFHFMIDLNQ
                     GPCVIKRITGCGAGNEYLSVTPNGDIYPCHQFVGNEEFKMANIFDEEIVLPENLKNMF
                     REAHVYTKEECKQCWNKFYCSGGCHANAINFNNDISKPYELGCEMQRKRTECSIMIQA
                     KLMLEGATN"
     gene            4504..5001
                     /locus_tag="PC494_001763"
     CDS             4504..5001
                     /locus_tag="PC494_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma carbonic anhydrase family protein"
                     /protein_id="HDF3912265.1"
                     /translation="MIRDYLEDKPLIDESVFVAKSADVIGNVKIGKDSSIWYNAVVRG
                     DEGPITIGENTNIQDCSIVHGDTETIIGNNVTVGHRSIVHGCKISDNVLIGMGSIILD
                     NAEIGEYTLIGAGTLITSNKKFPPGVLIMGSPGKVVRELTEEDKKYIDESYEWYLEAA
                     QNQKY"
     gene            5299..6963
                     /locus_tag="PC494_001764"
     CDS             5299..6963
                     /locus_tag="PC494_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AarF/ABC1/UbiB kinase family protein"
                     /protein_id="HDF3912266.1"
                     /translation="MRISYRNLKRYREIGYVLIKYGFSFIVERLNIEGIAYKIPLFDP
                     PEEIKNMTTGERMKRVLEELGPTYIKIGQILSTRKDLLDQDIIDEISKLRDDVEKFDS
                     NIAIDIFKEEVGLSIEEIFLEFKEEPIAAASIGQVYEGVLKTGEEVIVKIQRPNIEKI
                     IKSDLEILRTIANTLKDLKKDFNLDLVQMIEEFQTQLMRELDYTFEAINATKFSRIFK
                     NSDEVYIPKVYSEYNTKKILVMEKVNGTKLSDVEKIRRLGYNTKTIVEIGVRSFFTQV
                     LSHGFFHADPHPGNIFVIAKNKIAYIDFGMIGIIDNKTLNQLNEIALAGVEKNVDKII
                     YLLIEMDALNGEADIKGLRQDLLYLIHYYYDISIEKINVTDILNELFRFFRQYKIVMP
                     AQFVTLAKTVITLEGTSRTLNTDFSFGSMGKEFMKHHYKSKFNPKNVVLSSRQNVEEI
                     LLDIKTIPKQLKAILKNIERNNIKMQIEDVKMTRLENCIIELTSQISLSLVLASIIVG
                     SSLIIASPNIENNIWIKFTAIAGFFISFIIGLCLVIRSIRSKYKKD"
     gene            6976..9426
                     /gene="recJ"
                     /locus_tag="PC494_001765"
     CDS             6976..9426
                     /gene="recJ"
                     /locus_tag="PC494_001765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HDF3912267.1"
                     /translation="MKKWILKYKGKIEESEFSKKLNISPEICQILKNRGICTEKDSEI
                     FMNPSLDYLRDPFLMKDMQKAVDRIKLAVEKNEKIWIYGDYDVDGVSSTSILCLYFKS
                     IGYNVDYYIPNRLEEGYGINEDAIKLISSRGCDLIISVDCGITSVSEVNTANDLGIDV
                     IITDHHECQSEIPSAFAVINPKQEDCNYPFDSLCGCGVAFKMIQALTPKEEFKTSMYN
                     YLEIVTLATICDIVPLIDENRIIVKNGLKSMKEGKNIGLRELIKVCGVESDKIGSSHI
                     GFAIGPRINASGRLGYSYLGVELFTTQSQEEAVEIASILEEKNNERQMIEAKMYHEAE
                     EMLKSNSRYNDDKVLVLAKEGWQHGIIGIVASKLTEKYYKPTILLGIENGEATGSARS
                     IKGFNIFEALIKCKDLMTKFGGHEQAAGLSLDSDNVEILANEINKFADYNLTEDDMIE
                     NVNVEFELQENVINLNLVEELHKLEPFGLNNPNPRFIVRNYILKDLKVIGKNQQHLKL
                     SIEKEKSYECIGFNMSHLKSMYKVGDKVDVLFQLDENNYMGNRKVQFLLKDIRLARPK
                     SASNDKLSLKLMSKIIPKDTQSLYNISVSDFELFDGNTDINIFDYFEKDTLIISNSIN
                     GFYRAMSDISLIDLDFNINYNIIEDVSKNTDKLELIFSPNIDKIDLKRYNNIILYDYL
                     YNKGEYSYIYENKREESEIIKYYNKTDLLYLKNVVSNIVPSRDEFITIYKQALIKKEI
                     DLDMVNIRETFNVIPLKFFTILNVFRELNLLDFNLNYEKNSVLIRILPKPQKKLDLNE
                     SLILNNLKNLEKQYNSSY"
     gene            9439..9951
                     /locus_tag="PC494_001766"
     CDS             9439..9951
                     /locus_tag="PC494_001766"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HDF3912268.1"
                     /translation="MDLKNFIRNIDDFPKPGIDFKDVTTLFKDGDAFKYAVDSIVEEL
                     KDKDVDLVIGPEARGFLMGTPVAYALGVGFVPIRKPGKLPGEVESYEYGLEYGTDTLE
                     IHKDAIKKGQKVAIVDDLLATGGTMEAAAKLVEKLGGEVVSMQFLIELKFLNGREKLS
                     NYDVNSLIKY"
     gene            10025..12232
                     /locus_tag="PC494_001767"
     CDS             10025..12232
                     /locus_tag="PC494_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003229747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HDF3912269.1"
                     /translation="MHDKELQEIIEKIKVYAPNANFEMVEKAYNLAKKAHEGQYRKSG
                     EPYFIHPLAVANILIEMELDIETITAGLLHDVVEDTEYTYEDIKKEFGKEVADLVDGV
                     TKLGQIKYRSKEETQSENLRKMFLAMAKDIRVILIKLADRLHNMRTLKYMPPEKAKYK
                     AKETLEIYGGIAHRLGISKIKWELEDRALRFMDPEGYYDLVSRVSMKRSQREDYIQGI
                     VELLKDKFKDLSIPCDVYGRPKHFYSIYRKMQKKHKTFEEIFDLTAVRILVDNVKDCY
                     AVLGIVHTLWRPIPGRFKDYIAMPKPNMYQSLHTTVVGPDGEPLEIQIRTHEMHNIAE
                     NGIAAHWKYKEGISSKESKVEEKLQWLRQMMEWEKDLKDPQEFMDALKEDVFNSQVYV
                     FTPKGDVIELPAESTPIDFAYRVHTNVGNKCVGAKIDGRIVPIDYKLQNGNIVEVLTS
                     SNSNGPSRDWLNIVKTPNAKSRIRQFFKKERREENVDRGNTILEREFKKHDIPQKDPL
                     VEKYMALVAKKFNQPSVEDLIATVGYGGIMSSQVVSKVKDLYLKEVKKAKKEQQIQEE
                     DLNKHNISETEYSKKRKKNASQGIIVKGLDNILVRFAKCCNPLPGDEIVGYITKGRGV
                     AIHRADCPNANNNGDFFQNRLVEVSWSSAGKGKFEAEIQIKAIDRRGIVNEITHIVAM
                     DKLSLNGINARKGKDSIVSINLLVEVNDTEELKILMKKLKAIPGVESIYRMTN"
     gene            12257..12706
                     /locus_tag="PC494_001768"
     CDS             12257..12706
                     /locus_tag="PC494_001768"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003517065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HDF3912270.1"
                     /translation="MRAVVQRVSSSKVTVDENTIGQINKGLLVLLGVTHDDKSSDVDY
                     MIDKILNLRIFEDENDKMNLSLMDIGGELLVVSQFTLYGDCRKGRRPGFSNAARPELA
                     NNLYEEFVKKAKDKGVTVGTGQFAAHMMVELTNDGPVTILLDSSKSF"
     gene            12721..13335
                     /locus_tag="PC494_001769"
     CDS             12721..13335
                     /locus_tag="PC494_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HDF3912271.1"
                     /translation="MIIKKFVDSYFGVNTYVLGDEKTKKCAVIDPGGSLVETLSFVKE
                     NELNIEYIILTHGHGDHIGYVKDIKEKTGAKVVAHVDEKELLNDKNKNLSYTMRCGAQ
                     EFDADIYVNDKDKLELGELKMTFLHTPGHTQGCMCIRVEDEMFTGDTLFAGSIGRTDL
                     YSGDFNQMEKSLKKLCKYEDAVRVYPGHGPTSTLGVEKKTNPYM"
     gene            13426..14982
                     /locus_tag="PC494_001770"
     CDS             13426..14982
                     /locus_tag="PC494_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="coproporphyrinogen III oxidase"
                     /protein_id="HDF3912272.1"
                     /translation="MLYVFLKGHDYKYEVAELIKLFTSEFKFKDSNANNNIESKHLIN
                     RLIYENGVLFSSTEYYENGNLKYESIQNIENMNLEFLDGFDSSKTIEEFLNSLDSESK
                     RNFKKLCKENIKKSMFVVLKQVFNSYVPWGILTGIRPVKIVHNLMDKKLDDNSIRTIL
                     KDNYFIIDEKIDLALEIAKRERLFMYPIDKNKISLYVSIPFCPTRCVYCSFPSNSLKQ
                     FGHLKREYVYKLIEEIKGFAKVIKETKKEVETLYIGGGTPTTLDEEELDLLINSLFNE
                     LDLSKIKEFTVEAGRPDTITEQKLRVLKKHNVSRISINPQTMNDDTLVKIGREHRVSD
                     LVDCFNMARRMGFDNINMDIILGLIDEDLNMVKNTLEEIKKLSPESLTVHTLAIKRAS
                     NLNINMDRYKEHLTQYEEMVKMIDLSMKYAKDMGLNPYYMYRQKHMLGNLENIGYAKE
                     GYECIYNIQIMEEKQSNYALGAGAISKFVYVDEDRIERVENVKNVEQYIERVDEMIKR
                     KKEEVYKNVD"
     gene            14972..16234
                     /locus_tag="PC494_001771"
     CDS             14972..16234
                     /locus_tag="PC494_001771"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HDF3912273.1"
                     /translation="MLTKAPRGTKDITPKEAYKWRYVENKFREICALYGYEEMVTPIF
                     EHTELFKRSVGDTTDIVQKEMYSFKDKGDREITLKPEGTAGVVRAFIENKLYADTQPT
                     KLFYVTPCFRYERPQAGRQRQFHQFGIEALGSDTPSMDAEIIALAVQFFNEVGLNDLV
                     VSINSVGCPVCRKEYNALLKEYLDSKADILCDTCNERREKNPMRVIDCKNPTCKENIK
                     DIPFIADHLCDDCKSHFDKLQEYLKEMNINFVIDKTIVRGLDYYRKTAFEIISNDIGA
                     QSTVCGGGRYDGLVEQLGGPKGISGIGFGLGIERLLLTLEGNGIEIENPQSTDIFIVT
                     IGEKANTRSFKLLKDLRQNHISADKDHIERSVKAQFKYSDKINSKFTIVIGDDELKND
                     TATLKNMKTSEQTTVKLSTLVEELKQKL"
     gene            16308..18095
                     /gene="aspS"
                     /locus_tag="PC494_001772"
     CDS             16308..18095
                     /gene="aspS"
                     /locus_tag="PC494_001772"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HDF3912274.1"
                     /translation="METLKGLKRTHYCGELREKNINEEVVLMGWVQKKRNLGGLVFVD
                     LRDTSGLCQIVFDTDVDKEAFEKAEKLGAEFVIAVKGKVCERQSKNPNMPTGDIEIFA
                     TELRLLNKSETPPIYIKDDDDVSEALRLKYRYLDLRKPSMQRNLKLRHKVMNITRNYL
                     SNNRFCEIETPFLIAPTPEGARDYLVPSRVNPGKFYALPQSPQLYKQLLMVSGMDRYF
                     QIVKCFRDEDLRADRQPEFTQIDCEMSFVEQEDVMSMIEGLLEAIFKEVLDVELALPL
                     PKMTYAEAMSKYGSDKPDTRFGYELTDISDVVCNCGFKVFADATQPGKSVRGINVKGK
                     ADDFTRKQISSLEEHAKTYRAKGLAWMKVGQEGVTSPIAKFFNEEEMNAILTRMNAEV
                     GDLLLFVADKNSIVFDALGQVRLEVANRLNLLDKNVYNLLWVTEFPVFEEDEETGTFS
                     AMHHPFTSPMDEDLDKLEEGDKSSLRAKAYDIVLNGYEIGGGSVRISNSDVQSRMFKA
                     LGFTEERANEKFGYLLEAFKYGTPPHAGLAFGLDRLVMLLAGTDNIREVIAFPKNQNA
                     VCPMTNAPTLAEDEQLEELSIKVDIKDNE"
     gene            18554..19786
                     /locus_tag="PC494_001773"
     CDS             18554..19786
                     /locus_tag="PC494_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytosine permease"
                     /protein_id="HDF3912275.1"
                     /translation="MQEREELVLNPVPKEERVGWLAPLFNMLGSNIAISELMVGGTLI
                     LGMTLSNMIITSIIGNLILVAIIMIQGYIGYKEGLNTYVLAKGAFGEIGGKYLISLLL
                     GITSFGWFGVQAGVAGLSVQKIFPSVNLTLVTVILGLFMVVFALYGFKAMAKFNYLVI
                     PPLMILMVWGVFKAFSTYGVEAIYNYTPQTTMSMVEGLNIVVGLVIVGAIISPDQLRY
                     TRRVKDIWIISFLGLGIISLFQQVAAGVMSMGAPTWDITEVLANLGFGWVAFVILILA
                     SWSTNVSNAYSGGLALKTIFPNVKRNVLTLVAGLIGTIIAATGIIFKFQSFLSFLGIA
                     VPAIAGIMWCEYYFIQGRTYKHREGINWIAVISWLIGFAASYYSSKINFLIPPINGIV
                     VSMVIYYILMNCFGIKDK"
     gene            19800..20606
                     /locus_tag="PC494_001774"
     CDS             19800..20606
                     /locus_tag="PC494_001774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon-nitrogen hydrolase"
                     /protein_id="HDF3912276.1"
                     /translation="MGRKVKIGIIQQHSVLGNVKKNIEKAVEMIDDLGKQGADIICLP
                     ELFATGYNLESLGGVKTLELIREHNKYIEESMSEAAKRNNVYLISPYGTLEKGSTHVY
                     NSAVIFDRKGKIMGEYCKNHLWSLEAVYFKGGEKVEVYDADFGRFGVMICYDAGFPEV
                     SRELTLKGSEIIFIPSAWRIQDEDMWDLNVSQRALENTVYTVGVNLVSNDSNLILFGK
                     SKICNPRGTVITQLDTYREKYVLSEIDLDEIKKYREDIPYLKDRKSSYNI"
     gene            complement(20718..21587)
                     /locus_tag="PC494_001775"
     CDS             complement(20718..21587)
                     /locus_tag="PC494_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDF3912277.1"
                     /translation="MDLLHLKYFQTVARMEHITKASHKLNIAQPALSKTISSLEKELG
                     VQLFDRKGRYIVLNEYGRLFLKRVDSILDLVESSKKELQDTSLENSGEVKILSPAAAN
                     VLPSLLSNFRKLYPNITFNVSHTLPSSYKKSDFDLYISSSFTKLNSENSITLTCEEIL
                     LGVSINHPLSLKDEVYLSEVSDENFIVITKGENYREVIDILCESANFKPKIAFESDSP
                     YTIYALIKSLQGVGFICGKSWGLSQDPEIKLLHIKDIEFKRYLNLSWFSENYESKAVL
                     LFKNFLINYFKNI"
     gene            21959..23386
                     /locus_tag="PC494_001776"
     CDS             21959..23386
                     /locus_tag="PC494_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp14"
                     /protein_id="HDF3912278.1"
                     /translation="MKLTKSISSMLCLSLVLSLSPVAYANEISRTTVENTLVGQDRYQ
                     TAVEVSKKGWSSANEAVVVNSESIVDALAVTPFAKLKNAPILLTEKNNLNSQTEKELK
                     RLGVKKVYIIGLSSSVSNDVQKQLESNNLTTDRVGGSDRYQTALSIAKKIEGLKDISE
                     IAVVNGYTGLADAVSIASVAATNGMVILPVSDASGISSFKDFIESKNINKSYIIGSTN
                     AVSDKIKQSLPNSERIGGADRNETNGKVIEKFYTSNKLNNVFVAKDGMKNQNQLIDAL
                     AVGVLASKENSPVLIVGEQLSATQKSVFSNKNATSITQVGSGGNENAFKELKDLQANS
                     NNKRVMYVTNTDKVNIRNDATIEASVIGYLNNGDEVEVLDVLKTGWVKIKYNEGIGYV
                     SGSYLTNNKPDNSNENIKIKYVKEKDGLNVRKGPSTEDEKMGQLSYGSKVETVEMFAT
                     GWVKIKYNGGYGYVSNDYLSDTPVI"
     gene            complement(23463..23732)
                     /locus_tag="PC494_001777"
     CDS             complement(23463..23732)
                     /locus_tag="PC494_001777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3912279.1"
                     /translation="MKFEYYYLIQDIAGILLAFIGLRMSIIGFRILSMKGLSINTLLI
                     VIKYCLFTIAGLNLLISKFGIRHWIWSVCMLIISIIINPRIKVSK"
     gene            complement(23735..25177)
                     /gene="nhaC"
                     /locus_tag="PC494_001778"
     CDS             complement(23735..25177)
                     /gene="nhaC"
                     /locus_tag="PC494_001778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HDF3912280.1"
                     /translation="MKMNTERKIPSFRYSLLVMLAIIALTSVGIVVFNASITTMFLLS
                     WLIVVPAAMKLGYTNDEIEAFGFEVGKDAFQSNLIILSVGVLIAAWIAAGTIPTVVYS
                     GLTIITPKYFLLTTLIVCSLTSVATGTSWGTLGTSGIAMMSIGTSMGIPLGLTAGAVI
                     SGAFFGDKMSPLSDSTNLAAAVCKTDVITHMKHMFYTTGPAYVICIVLYTVIGFKYSN
                     NTIDYVQINQIKDVLNSNFHIGLVAMIPIIFLLLLLLLQKPPIISILSSAIMGLIIAV
                     FQEGEKIGDVLNYMLSGFTIDTGFVYADKLLNRGGIMSMAETVLLVFVVFVIAGILQK
                     TGFLEVLLQPLITKIGKSRTKLVGSTFIVSYFANAFSSSMMFTSVFVGTLMSPIYKEF
                     KLKPQNLSRIIEDTATLGGPLIPWNSNAVFCAQTLGVSPLEFIPYCFLSWITPIISFI
                     YGVTGFTMLTYTDDEIEELEIFDTAQRRVD"
     gene            complement(25202..26368)
                     /locus_tag="PC494_001779"
     CDS             complement(25202..26368)
                     /locus_tag="PC494_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HDF3912281.1"
                     /translation="MNYNFNEIVDRSNNFSSKWSEMEKKYGTNDLLPMWVADMDFKAA
                     PCIIDSLKNRLEQEIYGYTTRPDSYNESIVNWLYRRHNWKIKSEWLIYSPGVIPAISL
                     LINELTKANDKIMIQEPVYSPFNSVVKNNNRELIINPLQKLENGNYIMDYEDIENKIK
                     DVKLFILCNPHNPVGRVWTKDELKKLGDICLKHNVKIISDEIHSDIILKKHKHIPMAS
                     ISKEFEKNTITCMAPTKTFNIAGLQSSYVILPDEKDYKLLDDAFTRIDIKRNNCFSLV
                     ATEASYNNGESWLESFLEYLESNIDFAIKYINENMPKLKVRKPEGTYLLWVDFSALGL
                     SDEELESILVQKGKVALNQGNSFGIGGSGYQRINLACPRSMLEEALIRIKNAIN"
     gene            complement(26593..28713)
                     /locus_tag="PC494_001780"
     CDS             complement(26593..28713)
                     /locus_tag="PC494_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDF3912282.1"
                     /translation="MKQMELAIVSLKKDAGEIYENQIRQFLGDNLKINLYSFEEGNLK
                     FFKEKLILLSAYLKYDEIVKLSHYDAQIIVPKLTFEKNSIDMISKLEKDKIIYVYNLS
                     KDMAIETISLIHRLGIDNINILPCYPEIEFTPTDAVILTPGEKILPKFKNCEVIDLKY
                     RIIDLSCIVEIATKTKLKHLIKDDLIKKYVEKIIPTSYSTGELLLDANKFERQFDLLL
                     SIIDDGIICTNNDGIIQFYNHMARKILSINANEMIDSFVGDCIKDINFQSILTNKTPF
                     FEKLIKINHIDINLEIKHIQLNVFDGFILKMTKFSQLEKKQAKLRAQLVNSGNISKYT
                     FDDILGSSIQTINTKKIANKMAQSNSSILIIGESGTGKELFAQSIHSASRRKDGPFVA
                     VNCSTFQENLLQSELFGYDEGAFTGAKKGGKIGLFELANNGTIFLDEIGEMDLNSQSK
                     LLRVIQEKQVRRIGSNNVIDIDVRIIAATNRNLKELVSKNMFRRDLYFRLNVLPLKIH
                     PLRERPADIFEIFGSLKYDIPCNFILSEEVKEIFKMYRWEGNVRELRNLGEYFCYLEK
                     DIIEICDLPEYILDTIDSNYSRTVCNKVSDNIKKYQFNIGKDKNIMKYDYNFKRSLDE
                     YIFILDNLKKAYDLKERIGRKSLCKIALEENRFLTEQQIRNMLLELQDFGLVDILVGR
                     GGSIITSKGVEFLKNINRSNKLNS"
     gene            28946..29347
                     /locus_tag="PC494_001781"
     CDS             28946..29347
                     /locus_tag="PC494_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3912283.1"
                     /translation="MKKCLYCNRDIKSPNNKLAIKYDDNMNIYPCRAECKEKIEEYIA
                     KKPTYKFINILEVLLGVGGIFCFLSKWTIAAQVVLGIDALVIFLFPLAGFKMNGKLSM
                     EQTKNQSRSIAISILAFIVIITVLYFKQVGK"
     gene            29390..29683
                     /locus_tag="PC494_001782"
     CDS             29390..29683
                     /locus_tag="PC494_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensitive transcriptional regulator"
                     /protein_id="HDF3912284.1"
                     /translation="MEERKLAPNNEREALIKRLKRIEGQVKGIQKMVEQERYCVDILV
                     QISAIRSAINRVGTIILENHIKGCVAESIKHDDADKTEEMIKELMDTINKFTK"
     gene            29698..30138
                     /locus_tag="PC494_001783"
     CDS             29698..30138
                     /locus_tag="PC494_001783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SoxR reducing system RseC family protein"
                     /protein_id="HDF3912285.1"
                     /translation="MNQQGFIMEIVDDRTAKLKMQRHSACAACGKCATTNSAESKEIL
                     VEVDNTIGAKVGDHVEVSMDNMNVLKAAVMAYIIPLIALLVGTIGTYYILGAIGMTTG
                     VEAISGLVGICLTIICYLYLKKNDKKFRDSREFIPVITRILIDL"
     gene            complement(30230..30703)
                     /locus_tag="PC494_001784"
     CDS             complement(30230..30703)
                     /locus_tag="PC494_001784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HDF3912286.1"
                     /translation="MTDMSMILHFLFSGVATAGFAVFFNAPLYLLLPAGVTGGIGWIV
                     YVYLFNFTTNAVFAGFIAAALVSACSETLARKLKQPAIVFVIPGILPLIPGIGLYNTM
                     LSLIQKNYSLAMSKGTDALFLSAAIALGVLVVTSFVRTLNLLKIRKNFIPYRKSK"
     gene            complement(30703..31491)
                     /locus_tag="PC494_001785"
     CDS             complement(30703..31491)
                     /locus_tag="PC494_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HDF3912287.1"
                     /translation="MNQNEELEYKKNILKLALFVGELMIKNGAETSRVEDSVLRICRS
                     RGFYHVNIFTTPTVIIISDEKFDGFSFMKTIQSRGINLNKISLLNSFSREFVSDKEYD
                     IDNAIARLYEIQDVKPYPLWLFYSCTGIASACFACLLGGNYVLNFILTFIIAIFAAIT
                     YDKTMKISAISAFSCLVSSFLIALSGVLLVEIGILDDPKMLIVGAIMPLLPGVAFIKA
                     IRDLISGNLISGISRAFDAAMIIIAIASGVGFVLDTWYRIGGPF"
     gene            31819..33063
                     /locus_tag="PC494_001786"
     CDS             31819..33063
                     /locus_tag="PC494_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HDF3912288.1"
                     /translation="MFENLKKADPEIYESMKRELKRQQRNIELIASENIVSVPVMETM
                     GSHLTNKYAEGYSGKRYYGGCEYIDEVETLAIDRIKKIFGAEHANVQPHSGANANIGV
                     YFAMLKPGDVVMGMNLSQGGHLTHGAPVNISGQYYKFYEYGIDKDSGLIDFDEVRKIA
                     HEVKPKMIVAGASAYPREIDFKKFREIADEVGALLMVDMAHIAGLVAAGLHQNPCEVA
                     DFVTTTTHKTLRGPRGGVILCKEKYAKDIDKAIFPGIQGGPLEHIIASKAVCFKEALS
                     DEFKEYQVQVAKNAKALAEELIKRDFKLISGGTDNHLILLDLTNKNITGKAAEKRLDD
                     AYITANKNTIPFDPNGALVTSGIRLGTPAVTTRGMKEEDMAIIAEAIDLCLTYDEESK
                     ARTLVVGLTEKYPLYEEYNIMD"
     gene            33386..34483
                     /locus_tag="PC494_001787"
     CDS             33386..34483
                     /locus_tag="PC494_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-diphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase"
                     /protein_id="HDF3912289.1"
                     /translation="MKVLILTGKFGMGHYSASNSLSEDIKAKFDNSEIIIKDIFEYIM
                     PNYSDKMYKTFSILVNRGSSLYNLFYKCAENGKKDIKFTFSDYFLNKLDTLLHEVQPT
                     VVISTFPFCSQLVSRYKEKYNSNLPLITCITDISSHSEWISKNTDCYLVASKSTKEEL
                     VFKGIDESKIKVNGIPVKKEFKRIEHVNHSTKKNILIMGGGLGLLPKSEQFYKELNSL
                     EGVKTTVITGNNKKMYYKLYGRYENIEVVGYTNEVYKYMKDSDLIISKPGGITLFETI
                     YSELPILAFNPFLQQEIDNASFILNNEIGRILGKNKKYYVDEIKDLIYDDATLKEMSS
                     NMKELKKQFDNNTLENILFSLDEQGACRECM"
     gene            34474..35172
                     /locus_tag="PC494_001788"
     CDS             34474..35172
                     /locus_tag="PC494_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HDF3912290.1"
                     /translation="MYVVGLIIVVALIFLVHSIIPTYYNKLLNKKVLKNMAGENEIAL
                     TFDDGPDKRYTEKLLDVLKENDIQAMFFVVAKNAEKEPEIIKRMLRENHIVGLHSLEH
                     RNAWLYSYSYVKKDFIESTNIMKNLGVDVNYYRPPWGHTNIFSNSFVKKYNLKMTLWD
                     VMAEDWEKDSTVDIIINKLMSRTKENSIICLHDAGENSGGAVGAPERTIEALKIAIPK
                     LKASGLKFVTPERM"
     gene            35175..36239
                     /locus_tag="PC494_001789"
     CDS             35175..36239
                     /locus_tag="PC494_001789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flippase-like domain-containing protein"
                     /protein_id="HDF3912291.1"
                     /translation="MISKTEKKNKCLGSVAFLVLLMGITGYFVFRGQSVESLIKSLKG
                     ASPMFILIGFVMMFIYVACEGINIYLGMKALNQKTTLLKCMGYAFIGFYFSSITPSAS
                     GGQPAQVYYMKKDDINISYSSLILLVIVVIHQVVILAYSGIMFIMEREFILNNVSGMN
                     ILLIYGVITNVALVIGVIAIIFSKKLVNNFIISITNLLGKLRIIKDVESSRKVIISQI
                     EEYVKGAQYIKQNPKLVVQILVITIVQITAMFLVPFFVYKAFHLSTYTVFEILAIQSL
                     LNIAVSSLPLPGAVGASENSFMTLFKIFFPGHLLVPAMLLSRGISFYAFVAISGLICI
                     VVHVKSSEKVKAVKKVAYVR"
     gene            36422..37126
                     /locus_tag="PC494_001790"
     CDS             36422..37126
                     /locus_tag="PC494_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF3912292.1"
                     /translation="MNKEIPKKILVADDNPEIREIVEILLTGEGYEVIMATNGEEAVN
                     LVDSTIDLIILDVVMPVKTGFVACNEIREKTTAPILFLTAKTQDSDKVIGFSAGGDDY
                     LSKPFSYSELISRVKSLLRRYYIYQGKEKEREPNILKTKELCVNLDTQDVTLNGEPVF
                     LTTIEYSILILMLKNRKKVFSSENLYETIWDEQYFYTANNTIMVHIRNLRKKLEKDQK
                     NPQYIKTAWGKGYYID"
     gene            37119..38441
                     /locus_tag="PC494_001791"
     CDS             37119..38441
                     /locus_tag="PC494_001791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF3912293.1"
                     /translation="MINKIKPSKLGVILLIYVVISAAVAFILNIPFYSAVESIVKDVS
                     EGKVYFKREVNQLMDNFQTYVNNNGIRADDGDDIAKWNSDNWFVSMKIYKGNKVFYDT
                     LYYPNEVPDKSEENEFYSSPMARNYEIQFSDIKANIVVVALFRFRFQNFIEAISITFM
                     ALTFIITFLLLFSRKIKYLRKIEMGIKIVESGSLKYRIPVKGNDELSSLASSINEMSH
                     TLENQLIKEREMKNKNKDIVTSISHDVRTPLTSVICYLDLIKDHKYNSPEQLEQYIKN
                     VRSKAYQIKDLTDDLFTHFVNSGEEVSKGYEKINANEFIFQLLLDSSYTLEEKGFHIT
                     IENELYNQYHIYVDVTQFRRIFDNLCSNIIKYARKDKPIVFLIKVEDSKLLIIQKNRV
                     SNFSKNVESFGIGIKNCEKIVAYHNGSINVNSDDKEFAIEISIPAKES"
     gene            38628..40001
                     /locus_tag="PC494_001792"
     CDS             38628..40001
                     /locus_tag="PC494_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3912294.1"
                     /translation="MVLTGAHYIYILFMVIILITMIMKKDTIVPCILGVFFMGLFFEK
                     NIFGAITAVFNSFIISLNELGPIILIIAIMVALSKALEANNAIQYMVRPFSRVIKNSN
                     TAFFVTGFVMLVLSWFFWPTPAVALVGAVFLPVAMRAGLPAIGVAVALNLFGHGLALS
                     TDFVIQGAPSITAGAAGVAVSYVINDGMILFWVMGIVTISMAFYTLKRDINKGMFREE
                     LKGFESEEVEEFNGKSKIATILVALGFLADIIAMYIFDLKGGDASALLGGTAVFLIII
                     INVINFGKDSLENVCENIIDGFVFGIKIFGAIIPIAAFFYMGEVAPLTGVFGKVLAPG
                     SQGLLSDIGIALSQTIPLNKFAVSGIETVVGAITGLDGSGFSGISLVGSLASVFGTAI
                     NASVGALAALGQISGIWVGGGCLVPWGLISAAAICGVSPIELAKRNFVPVITGLVVTT
                     IVAMFII"
     gene            complement(40373..41311)
                     /gene="pdaA"
                     /locus_tag="PC494_001793"
     CDS             complement(40373..41311)
                     /gene="pdaA"
                     /locus_tag="PC494_001793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="delta-lactam-biosynthetic de-N-acetylase"
                     /protein_id="HDF3912295.1"
                     /translation="MFRKVLHYLTLLSISIFFIVGCSNSQNNQNENQNKETQLQEDKE
                     KIDSGKDTSNVIVSDGTDKPSKATTNNDDNKLDVSSLDNTTLDWFYIPNNKHKTPEVN
                     TDIEFKFSDYDALYNGPTKDGQKTLYLTFDEGYENGYTTKILDTLKQNQVKAVFFVTT
                     PYIKENKDLVKRMVSEGHIVGNHSKTHPSMPTKTSNLKNFNDELYDVEKLYKDVTGKD
                     MVKFFRPPMGKYSEKSLAMTKNLGYKTVFWSFAYRDWDTDKQPSHEEATQKIMDNLHD
                     GSILLLHAVSKTSTEILNDFISNARKLGYEFELLEY"
BASE COUNT        16036 a         4708 c         7072 g        13768 t
ORIGIN      
        1 aaaatttgaa aaaaatcact ataaatgagt aataaatata aatagtgtat actaatggga
       61 tggaaaatgt ccactattaa ctttattacc ccacatatat aagataaaat tattaatata
      121 aaatataatc tatcgacaat gaatagactt ttaaataaac ttaatataaa attaattaaa
      181 taagtgctta aaaacgattt actttaatga tagaatcata ttaaaggagg ataattttat
      241 ggatataaag aataaaatta aatctatatt tttaccagaa aaaaatgact atttagatga
      301 tgaagaattt gagtatgata tagaaaataa tgaagaagat ttaaaggaag ataacaaagt
      361 acatttaaat gatttaagta gagtaaaata tgattacaga gagttaaaag acatagaaaa
      421 ccaaacagaa gagatatgtc tgctagcagt aaagcaggat ggtactataa ttgagtttgt
      481 aaaggacaag acttataaag tatgtatgga agcagtaaaa cagacatata aatctcttaa
      541 gtatataaca aatcaaaatg aggatatttg tatagaagca gtaaaacaga actacagagc
      601 tttgtactac ataaataata agacagaaaa tgtactaatt gaggctataa aaaatgcatc
      661 aacttatgat gtcatggaag tatttaaatt tgtggaagag caaacagaag atgtatgtct
      721 agcatttata gaaagggcat ctaaaaatga tgttgcagag atattaaaag gaataaaaga
      781 gcaaactcca gccatatgtt tagaagctgt aaaaaaagat ggaaaatctt tagcttatgt
      841 aaaggaacaa agtaatagta tatgtttaga agctgtaaaa gaaaactaca gtgcactatc
      901 ttgtgtaaaa gagcaaactg aagaaatatg tatagaagca gtaaaacaga atgactttgc
      961 attgtattat gtaaatgaac agacagaaaa aatatgtatg gaagcagtaa aaagaagtta
     1021 tatggctcta cagtatgtaa ataagcaaac agaagagatt tgtttggaag cagtaagaat
     1081 tgatggaaga gcattacagt acgtaaaaga gcaaacagaa gaaatttgct tggagtcagt
     1141 tagacaaaat ggaaaagtac tgcaatatgt aaaaaaacag actgaaaata tatgtataga
     1201 agcagtaaga ggttcatttg aagaacttga aataaaagaa atattaagtt atgtaaagat
     1261 accaacagaa agaatatttg tagaagcagt aaagcaaaat ggaaaaattc ttaaatatgt
     1321 agaaaatcag acagaattaa tatgtttaga ggcagtaaga gaaaactata atgctttagc
     1381 ttatgtaaag gaacaaacag aaaagatttg tttagaagca gttaatcaaa gttatgaagc
     1441 gcttaaatat gtgaaagaac aaacagaaga agtttgtcta aaagcagtaa aacaagatta
     1501 tagaatgttg aaatatgtaa ataatcaaac agaaaaaata tgtttagaag cagtaaagca
     1561 aaattataga gctttagaat ttgttgataa tcaaacagaa aaagtttgtc ttgaagcagt
     1621 aaaacagaat agaaaagcac tacagtatgt aaaacaaaaa caaagttaaa aggctaaaat
     1681 atatagaaaa tatatgcaaa taaataaaat ttgatatttt gtaataaata aaatgggtat
     1741 ctcaaaagga actttttagt ttgtgaggta ctctttttat atgaaataaa atatattttt
     1801 agacttttaa caatggggaa aaggtttatt tctattttga cataggcttt ttatgcatat
     1861 aaagcttgat aaaattgttt tattataatt gttttgttat ataaataata agaagaaaat
     1921 tatataggtc tttttttgac cagttttaca tttttaacaa ctagttttgt aaagtatatt
     1981 gaattttctc aaaaaagaat gtactctata tatgtaaaat ttttttggag gtaaaaatgt
     2041 ttaaaagata tgctgaaaaa atgacatctg ttttaatttg taataatatg atagataata
     2101 atgaatctaa agtctattct tatggatttg aaatattaat agctttcata gttaatataa
     2161 ccaccatgct gtttataggt tttttatttg gtaaatttac atatgtatta ttttttttaa
     2221 tgtgttattg tccaataaga caattttcag gagggtatca tgcagacaat tattttagat
     2281 gcttattaac ctttattttt ataattttat ccacaatctt aattatagaa aatataaata
     2341 tagacttatt taaaaatatt attatgatta ttgcaagtgt tagttgggtt ggaatttgtg
     2401 ttctgtgccc aatagaacat aggagtaacc ctataagtga tagggaaaag ttggtttata
     2461 agaaaactgc tatatttata tctacagtag tgttattgat aacaatttta agtctttctt
     2521 tgagtatatt tgtagattat ttcacatata gcgcatttgc catgttttgg atttttgtga
     2581 tgttagtatt aggtaagtta aaagctaaag tataagtaaa atatgtatga gggagagtta
     2641 agttatgaaa aagtttattg taagatttat gaagtttgct agctcattgg cacttagcac
     2701 tgctattttg tcagctaata gtacctgtcc ttggattatt catcagccta aagtacccaa
     2761 agaaatcagc aatctaaaga agacaaatta aatacaagca cttatttata caaaattatc
     2821 aggaaaaaag aaattattat attttaataa gattaaaaca atataaaatc agatacaaaa
     2881 tttattttat ttattttata ggagcctaat acctatttgg taatatatta gtgcgccaat
     2941 ttagggggat atagtgtatt taatgaaatg acttacggag agtaagtcat ttttgtattg
     3001 tatgtatttt atgtaaactt atgatataat gaagggtaaa gtttaattaa aataataaaa
     3061 aactttagta tagatagtaa tttaggaggt agagtatgag tatgatacat aagttttcta
     3121 tgaatggata taatatcgtt ttagatgtga atggtggagc tgttcatgtg ttagatgatg
     3181 ttgcatacga tttgttagat ttttataaag aaaaaagtaa agaagaaata ttagagatat
     3241 taaaatcaaa atatcaagaa gaaaaaataa atgaagcata tgaagaaata ttaaatttgg
     3301 aaaaagaggg tcttttatat acagaagata catatcaata tcatccaagc tttgtacata
     3361 gagagcctgt agtaaaagct ttatgtttaa atgtagctca tgattgtaac ttaaaatgta
     3421 aatactgttt tgcagctcaa ggtgattttg gaggagaaaa agaacttatg agttttgaag
     3481 ttggtaaggc agcaattgac tatttgattg ctaattcagg aagtagaaag aacctagaga
     3541 tagatttctt tggtggagag cctttgatga actttgaagt tgtaaaacaa ctggttgact
     3601 atggaagaag tgtagaaaaa gattataata aaaatataag atttacaata actacaaatg
     3661 gtgtactgtt aaatgatgag attatagatt atataaatga aaatatgcat aatgtagttt
     3721 taagtttaga tggaagaaaa gaagttaatg ataatatgag accaacttta aatgataaag
     3781 gaagttatga tattacatta ccacgattta agaaacttgt ggaaaaaaga gcaaaagata
     3841 agtattatta tataagaggt acttttacaa gggataattt agatttttca aaagatgtta
     3901 tgcattttgc agatttagga tttaaattaa cctctgtaga gccagtcgtt ggagatgaga
     3961 gtaatccata tgcacttaga gaagaagatt tacctaagat atttgaagag tacgaaaaat
     4021 ttgctgtaga gtatgcagat agacaattac aaggagatgg atttaaattt ttccatttta
     4081 tgatagacct aaatcaaggt ccatgtgtaa taaagagaat aactggatgt ggagctggaa
     4141 atgagtatct ttctgtaact ccaaatggag atatctatcc atgtcatcaa tttgttggaa
     4201 atgaagaatt taaaatggca aatatatttg atgaagaaat agtacttcca gaaaatttaa
     4261 aaaatatgtt tagagaagct catgtatata ctaaagaaga gtgtaaacaa tgttggaata
     4321 agttttactg ttcaggtgga tgtcatgcaa atgcgataaa ctttaataat gacatatcaa
     4381 aaccatatga attaggctgt gaaatgcaaa gaaaacgtac agagtgctct ataatgatac
     4441 aagctaagtt aatgttagaa ggagcaacca actaaattta tattttaaag gagttgttta
     4501 tatatgatta gagattattt agaagataaa cctttaattg acgaaagtgt atttgtggca
     4561 aaatcagcag atgtaattgg aaatgttaaa ataggcaaag attcaagtat atggtacaat
     4621 gcagtagtta ggggtgatga aggaccaata actattggag aaaacactaa tatacaagat
     4681 tgttctatag tgcatggaga tacagaaact ataattggta acaatgtaac agttgggcat
     4741 aggtctatag ttcatggttg taaaattagt gataatgtgt taattggtat gggttcaata
     4801 atattggata atgctgaaat aggagaatat actctgatag gagcaggtac actaattaca
     4861 tctaataaga agtttccacc aggtgttttg ataatgggtt ctcctggtaa ggttgttaga
     4921 gagcttacag aagaagataa aaaatatatt gatgaatctt atgaatggta tttagaggca
     4981 gcacaaaatc aaaaatatta gtttaaagag tggttgtttc aaaacatatt taaatctgtt
     5041 ttgaggcaac cactaattta ttttattaga ttttgttgat attttagttt tcaaaaagta
     5101 tttgattaaa ccagatataa aatgtcaaaa ataaaaatta actgagttaa ataattttaa
     5161 taaaattggt agtatatgtg ataaaattaa atattaaaga ggatatagga tattagaata
     5221 tcaattggtg aaataatgtc atatacgata aattaaggtg taagtttttg ggtataccta
     5281 tcttaggagt gaaaagattt gagaataagt tatagaaatt taaagcgata tagagaaatt
     5341 ggatatgttt taataaagta tggttttagt tttattgtag aaagactaaa tatagaagga
     5401 attgcctata aaataccact atttgaccca ccagaagaaa taaaaaatat gacaactggt
     5461 gagagaatga aaagagtttt agaagaacta ggacctacat atataaaaat aggacagata
     5521 ttgagtacaa gaaaagactt gttagaccag gatataattg atgaaatatc aaaactcaga
     5581 gatgatgtag agaaatttga ttcaaatata gctattgata tatttaaaga agaagtgggt
     5641 ttaagtatag aagaaatatt cttagaattt aaagaagaac caatagcagc agcttcaatt
     5701 ggtcaagttt atgaaggtgt acttaaaacg ggagaagaag taatcgtaaa aattcaaaga
     5761 ccaaatatag agaaaataat aaaatctgat ttagagattc ttagaactat tgcaaatact
     5821 ttaaaagatt taaaaaagga ttttaattta gatttagtac agatgattga agaatttcaa
     5881 actcaattaa tgagggaact tgattataca tttgaagcta taaatgcaac taaattctct
     5941 aggatattta aaaatagtga tgaagtatat atacctaaag tatattcaga atataatact
     6001 aagaaaattt tagtaatgga aaaagttaat ggtacaaagt taagtgatgt agaaaaaata
     6061 aggagactag gttataacac aaaaactatt gttgaaatag gcgttaggtc attttttaca
     6121 caggtattat ctcatggatt ttttcatgca gacccacatc caggtaatat attcgtaatt
     6181 gctaaaaata agatagcata tatagatttt ggaatgattg gaattattga taataaaact
     6241 ttaaaccaat taaatgaaat tgcattagca ggtgtagaaa agaatgttga caagataata
     6301 tatctattga tagaaatgga tgcattaaat ggagaggctg atattaaggg acttagacag
     6361 gatttacttt atctaataca ttattactat gatatttcta tagaaaaaat aaatgtaaca
     6421 gatatattaa atgaactatt taggtttttt agacagtata aaatagtcat gcctgcacaa
     6481 tttgtaactc ttgcaaagac agttataaca ttagaaggaa caagtagaac tttaaacaca
     6541 gatttttctt ttggttctat gggaaaagag tttatgaaac atcattataa gagtaaattt
     6601 aaccctaaaa atgttgtttt aagttcaaga caaaatgtag aagaaatatt actggacata
     6661 aaaactattc caaagcaatt aaaagcaatt ttaaaaaata tagaaagaaa taatataaaa
     6721 atgcaaattg aagatgttaa aatgacgagg ttagaaaatt gtataataga gctaacatct
     6781 caaatatctt tgagtttagt gttggcatct attatagtag gttcttctct tataattgca
     6841 tctccaaata tagaaaataa tatatggata aaatttactg caatagcggg tttctttata
     6901 tcctttataa taggcctttg cttagttata agaagtatta ggtcaaaata caaaaaagat
     6961 tagggggaat taaatttgaa aaaatggata ttgaagtata aaggtaagat agaggaaagt
     7021 gaatttagca aaaaacttaa tatttccccg gaaatctgcc aaattttaaa aaatagaggg
     7081 atatgtactg aaaaagattc agagatattt atgaatccat ctttagatta tttaagagac
     7141 ccttttttaa tgaaagatat gcaaaaagct gttgatagaa taaagttagc agttgagaag
     7201 aacgaaaaaa tttggattta cggagattat gatgttgatg gtgtatcatc tacatctatc
     7261 ttgtgcttat attttaagag tataggttac aatgttgatt actatattcc taatagatta
     7321 gaagaagggt atggtataaa tgaagatgct attaagctta taagctctag gggatgtgac
     7381 ttgattataa gtgttgactg tggaattaca tcagtgtctg aggtcaatac agcgaatgat
     7441 ttgggcatag atgttataat tacagaccat catgaatgtc aaagtgaaat tccatcagcc
     7501 tttgcagtaa taaatccaaa acaagaagat tgtaattatc catttgattc actatgtgga
     7561 tgtggtgtag catttaaaat gattcaagcc ttgactccaa aagaagaatt taaaactagt
     7621 atgtataatt atttggaaat agtaacacta gcaactattt gtgatattgt tccacttata
     7681 gatgaaaata gaataattgt aaaaaatggt ttaaaatcaa tgaaagaagg caaaaatatt
     7741 ggattaaggg agcttataaa agtttgtggt gtagaaagtg ataagatagg ttcttctcat
     7801 ataggttttg caataggtcc taggataaat gcttcaggtc gattgggata ttcttactta
     7861 ggagtagagc tatttactac tcaatcacaa gaagaggcag tagaaatagc tagtatattg
     7921 gaagaaaaaa ataatgaaag acagatgata gaagctaaga tgtatcatga agctgaggaa
     7981 atgctaaagt ctaatagcag atacaatgat gacaaggtgt tggttttagc taaagagggt
     8041 tggcaacatg gaataatagg aattgtagca tcaaagttaa ctgaaaaata ctacaaacca
     8101 acaattcttc taggtataga aaatggggag gctactggtt cagcgaggtc aataaaagga
     8161 tttaatatat ttgaagctct cataaagtgc aaagacttga tgactaagtt tggtggtcat
     8221 gaacaagcag cagggttatc cttggattca gacaatgtag aaattttagc aaatgaaata
     8281 aataaatttg cagattataa tttaactgaa gatgatatga tagagaatgt aaatgtcgag
     8341 tttgaattac aagaaaatgt aataaattta aatcttgtag aagaattaca taagttagaa
     8401 ccctttggat taaataatcc taatcctaga tttatagtta gaaattatat tttaaaagat
     8461 ttgaaagtta taggtaagaa tcaacaacat ctgaaattaa gtatagaaaa agagaaaagc
     8521 tatgaatgta taggatttaa tatgagtcat ttaaaatcaa tgtataaagt aggagacaaa
     8581 gtagatgtac tattccaatt agatgaaaat aactatatgg gaaataggaa agtacaattt
     8641 ttacttaaag atatacgatt agctcgacct aaaagtgcaa gtaatgacaa actttcattg
     8701 aaattaatgt caaaaataat accaaaagat actcaaagcc tgtataatat atctgtgtct
     8761 gattttgaat tatttgatgg aaatacagat ataaatatat ttgattattt tgaaaaagat
     8821 acactaataa tatctaattc tataaatgga ttttatagag caatgtcaga tatatcactt
     8881 atagatttgg attttaacat aaattacaat attattgaag atgttagcaa aaatactgat
     8941 aaattagagc ttatattttc tcctaatatt gataaaatag acttaaaaag atataataat
     9001 attattcttt atgattattt atacaataaa ggcgaatatt cgtatatata tgagaataaa
     9061 agagaagaaa gtgaaattat aaaatattat aataaaacag acctattata tttaaagaat
     9121 gtagttagta atatagttcc atcaagagat gaatttataa caatttataa acaagcactc
     9181 ataaaaaaag aaattgattt ggatatggta aatataaggg aaacttttaa tgtaattcca
     9241 ttaaagtttt ttacgatatt aaatgtattt agagaattaa atttacttga ctttaattta
     9301 aattatgaaa aaaattctgt actcataaga atattgccaa aaccacagaa aaaattagac
     9361 ttaaatgaga gtttaatact caataatcta aaaaatttag aaaaacaata caatagcagt
     9421 tattaggagg cgtttcccat ggatttaaaa aactttataa ggaatattga tgatttccca
     9481 aagccaggca tagattttaa agatgtgaca actctattta aagatggaga tgcatttaaa
     9541 tatgcagtgg attctatagt tgaagaattg aaagataaag atgtagattt agtaatagga
     9601 ccagaagcaa gaggattttt gatgggtaca cctgtagcat atgctttagg agtaggattt
     9661 gttccaatta gaaaacctgg aaagttacca ggtgaagttg agagttatga gtatggatta
     9721 gagtatggta cagatacttt agagatacat aaggatgcaa ttaaaaaggg tcaaaaagta
     9781 gcaatagtag atgatttatt ggctactggt ggaactatgg aagccgctgc caagcttgta
     9841 gaaaaattag gtggagaagt agtttctatg caatttttga ttgagctaaa attcttaaat
     9901 gggagagaaa agttgtctaa ctatgatgtt aattctctta taaaatacta gtacttttat
     9961 aatagttggt ataacaccaa ctattttcat atatattaaa attttataca aaataggtgg
    10021 ttatatgcat gataaagaat tacaagaaat aattgaaaaa ataaaagttt atgcacctaa
    10081 tgcaaatttt gaaatggttg aaaaagccta taatcttgca aaaaaagcgc atgaaggaca
    10141 atatagaaaa tctggggaac catactttat tcatccatta gcagttgcaa atattttaat
    10201 agagatggaa ttagatattg aaactataac agcaggttta cttcatgatg ttgtagaaga
    10261 tacagaatat acctatgaag acataaaaaa agaatttggc aaagaagtag cggatttggt
    10321 tgatggagta actaaacttg gtcaaataaa atatcgttcg aaagaagaaa ctcaatctga
    10381 aaatttaaga aaaatgtttt tggcaatggc gaaggatata agggttatac ttataaaact
    10441 tgctgataga ttgcacaaca tgagaacatt aaaatacatg cctccagaaa aagcaaagta
    10501 taaagcaaaa gagacacttg aaatttatgg tggtatagct catagattag gaatttccaa
    10561 gataaagtgg gaactagaag acagagcatt aagatttatg gacccagaag ggtattatga
    10621 tttagttagt agagtatcaa tgaagagaag tcaaagagag gattatattc aaggaattgt
    10681 tgaacttctt aaagataagt ttaaagattt aagtatacca tgtgatgtat atggtagacc
    10741 aaagcatttt tacagtatat atagaaagat gcaaaaaaaa cataagactt ttgaagagat
    10801 ttttgattta acagcagtaa ggatattggt tgataatgta aaggattgtt atgcagtact
    10861 tggtatagtt catacattat ggagacctat tccaggaaga tttaaagatt atatagcaat
    10921 gccaaaaccc aatatgtatc aatcattaca caccactgtt gtaggtcctg atggagaacc
    10981 tttagagata caaataagaa ctcatgagat gcataatata gctgaaaatg gtatagcagc
    11041 ccattggaaa tataaagaag gtatctctag caaagaatca aaggttgaag aaaaacttca
    11101 atggttgaga cagatgatgg agtgggaaaa agatttaaaa gacccacaag agtttatgga
    11161 tgcacttaaa gaagatgtat ttaatagtca agtttatgta tttacgccaa aaggagacgt
    11221 aattgaatta ccagcagaat caacacctat agattttgcc tatagggttc atacaaatgt
    11281 aggtaataaa tgtgtaggag ctaaaattga tggaagaata gttcctattg attataagct
    11341 tcaaaatggt aatattgtcg aggtacttac atcatctaat tctaatggac caagtaggga
    11401 ttggcttaat atagtgaaga ccccaaatgc aaaaagtaga attagacaat ttttcaagaa
    11461 ggaaagaaga gaagaaaatg ttgaccgtgg aaatacaata ttagaaagag aatttaagaa
    11521 gcatgatata ccacaaaaag accctcttgt tgaaaaatat atggcattag ttgctaagaa
    11581 atttaatcag ccaagtgttg aggacttaat tgccactgta ggttatggtg gtataatgtc
    11641 atctcaagtg gtatctaagg taaaagacct atatttaaaa gaggttaaaa aagctaaaaa
    11701 ggaacaacag atacaagaag aagatttaaa taaacacaat ataagtgaaa cagaatacag
    11761 taaaaagaga aagaaaaacg catcacaagg aattatagta aaagggcttg acaatatctt
    11821 agtaagattt gctaagtgtt gtaatcctct tccaggagat gaaattgtag gatatattac
    11881 taagggtagg ggagtagcca tacacagagc tgattgccca aatgcaaaca ataatggtga
    11941 tttcttccaa aatagattgg tggaggtttc atggagttca gcaggaaaag gtaagtttga
    12001 agcggaaatt caaataaaag ctattgacag aagaggaatt gttaatgaaa taactcatat
    12061 tgttgcaatg gataaactta gtttaaacgg aataaatgca agaaaaggta aggatagtat
    12121 tgtaagtata aacttacttg tagaggttaa tgacacagag gaattaaaaa ttctaatgaa
    12181 aaaattaaaa gcaattcctg gtgtagaaag tatttataga atgacaaatt agagttaaaa
    12241 taatagggag gaaactatga gagcagtagt gcaaagagta tcttcatcta aagttacagt
    12301 agatgaaaac actataggtc aaataaataa ggggttacta gtattgttag gagtgactca
    12361 tgatgataaa tcaagtgatg tagattatat gattgataaa atattgaatc tgagaatttt
    12421 tgaagatgaa aatgacaaga tgaatttatc tctaatggat ataggtggag agcttttagt
    12481 agtatctcaa tttactttat atggagattg cagaaaagga agaagacctg gatttagtaa
    12541 tgcagctaga ccagaacttg caaataacct ttatgaagaa tttgtaaaaa aagcaaaaga
    12601 taaaggtgtg acagttggta caggtcaatt tgcagctcat atgatggtag agttaactaa
    12661 tgatggtcca gtaacaatac tattagactc aagtaaatct ttttaagggg gaaaacttta
    12721 atgattataa aaaaatttgt agatagttat tttggagtaa atacttatgt attaggtgat
    12781 gaaaagacta aaaaatgtgc agttatagac ccaggtggaa gtttagtaga gacattaagt
    12841 tttgtaaaag aaaatgaatt aaatattgaa tatattatcc ttactcatgg gcatggagac
    12901 catataggat atgttaagga tattaaagaa aaaactggtg ctaaagtagt tgcacatgtt
    12961 gatgaaaaag aattattaaa tgacaaaaat aaaaatctaa gttatacaat gagatgtgga
    13021 gcacaagagt ttgatgcaga tatctatgta aatgataaag acaagcttga acttggtgaa
    13081 ttaaaaatga ctttcttgca tactccagga catactcaag gatgtatgtg tataagagtt
    13141 gaagatgaaa tgttcacagg agatactttg tttgctggaa gtattggtag aactgattta
    13201 tatagtggag actttaacca aatggaaaaa tcacttaaga aattatgtaa atatgaagat
    13261 gctgttagag tatatcctgg acatggacca accagtactc taggggttga aaagaagaca
    13321 aatccttaca tgtaatttta tattagtatt taaaaaagta taaaatattt aataactata
    13381 ttagtgaggg ggttcttcta ctgttaaata gaaggagtta agttgatgtt gtatgttttt
    13441 ttaaaaggac atgattataa gtatgaagta gcagaactta taaaattgtt tactagtgaa
    13501 tttaagttta aagactctaa tgctaacaat aatatagagt caaagcattt aataaataga
    13561 ttgatttatg agaatggtgt attattctca agtactgaat actatgaaaa tggaaactta
    13621 aagtacgagt caatacagaa tatagaaaat atgaatcttg aatttttaga tggatttgat
    13681 agcagcaaaa cgattgaaga atttcttaat agcctagata gtgaaagtaa gaggaacttt
    13741 aaaaagctgt gtaaagaaaa tatcaaaaaa agcatgtttg tagtgcttaa acaagtattt
    13801 aattcttatg taccatgggg aattttgact ggtattagac cagtcaaaat tgtccacaat
    13861 ttaatggata aaaagctaga tgataatagc ataagaacca ttctaaaaga taattatttt
    13921 ataatagatg agaaaataga tttagctctt gaaatagcta aaagagagcg attatttatg
    13981 tatcctatag ataaaaataa aatttctctt tatgtaagta ttccattttg tccaactaga
    14041 tgtgtatatt gttcatttcc ttcaaattca ttaaaacaat ttggacattt aaaaagagaa
    14101 tatgtttata aattgattga agaaattaag gggtttgcca aagttattaa ggagactaag
    14161 aaagaagttg aaactctata tattggtggt ggaactccaa ctacacttga tgaggaagaa
    14221 ttagatttgc ttataaattc attgttcaat gaattagatt taagtaaaat taaagaattt
    14281 actgtagaag caggtagacc tgacactatt acagaacaaa aactaagagt gttaaaaaaa
    14341 cacaatgtta gtagaattag tataaatcct caaactatga atgatgatac cttggtaaag
    14401 attggaagag agcatagagt atctgattta gtagattgct ttaatatggc tcgtagaatg
    14461 ggatttgata atataaatat ggatataatt ttaggtctta tagatgaaga tttaaatatg
    14521 gtaaagaata cattggagga gataaaaaaa ctttctcctg aaagccttac agttcataca
    14581 ttagccataa agagagcatc caacttaaat ataaatatgg ataggtataa agaacatcta
    14641 acacaatatg aagaaatggt aaaaatgata gatttatcaa tgaaatatgc aaaagatatg
    14701 ggattaaatc catattatat gtatagacaa aaacatatgt tgggaaattt agaaaatata
    14761 ggttatgcta aagaaggata tgagtgcatt tataatatac agattatgga agaaaaacaa
    14821 agtaactatg cattaggtgc aggtgctata tcgaaatttg tttatgtaga tgaagataga
    14881 attgaaagag tagaaaatgt aaaaaatgtt gaacaataca ttgaaagagt agatgaaatg
    14941 ataaaaagga agaaagaaga ggtatataaa aatgttgact aaagctccta gaggaactaa
    15001 agacataact ccaaaagagg cttacaaatg gcgttatgta gaaaataaat ttagagaaat
    15061 atgtgcttta tatggatatg aagaaatggt aacacctata tttgaacata cagaactttt
    15121 caagagaagt gttggagata ctacagatat agttcaaaaa gaaatgtatt cttttaaaga
    15181 taaaggtgat agagaaatta ccctaaagcc agaaggtaca gcaggtgtag taagagcatt
    15241 tatagaaaat aaattatatg cagatactca accaacaaaa ttattttatg taacaccttg
    15301 ttttagatat gaaagaccac aagctggtag acaaagacaa tttcaccaat ttggaataga
    15361 agcacttgga agtgatactc cttcaatgga tgctgaaata atcgcactag ctgttcaatt
    15421 ttttaatgaa gttggattaa atgatttggt agtgagtata aattcagttg gctgtccagt
    15481 ttgtagaaaa gagtacaatg ctttattaaa agagtatctt gactcaaaag ctgatatatt
    15541 gtgtgatact tgcaatgaga gaagagaaaa aaatccaatg agggttatag actgtaaaaa
    15601 tcctacatgt aaagaaaata tcaaagatat accatttatt gcagaccatt tgtgtgatga
    15661 ttgtaaatct cactttgata aacttcaaga atacttaaag gaaatgaata taaactttgt
    15721 aattgataaa acaatagtta gaggcttaga ttactataga aaaactgctt ttgaaattat
    15781 atctaatgat ataggagctc aaagtactgt atgtggtgga ggaagatatg atggtcttgt
    15841 tgaacaatta ggaggaccaa aaggtataag tggaattggg tttggactag gaattgaaag
    15901 acttttactt acacttgaag gtaatggaat tgaaatagaa aaccctcaat ctacggatat
    15961 atttatagta actataggtg aaaaagcaaa tacaagaagc tttaaattgt taaaagactt
    16021 gagacaaaat catataagtg cagataaaga ccatatagag agaagtgtta aagcacaatt
    16081 taaatattca gataaaataa attcaaaatt tacaatagta attggagatg atgagcttaa
    16141 aaatgacact gcgacattaa aaaatatgaa aacatcagag caaactactg taaaattaag
    16201 tacattagtt gaagaattaa agcaaaagct gtaaaataag aaagtatgat gttttgtgta
    16261 ttagataaat atatagcatt aaaattaaat aaaatggagg tagtatcttg gaaactttaa
    16321 agggtttaaa gagaactcac tactgtggag agttgagaga aaaaaacata aatgaagaag
    16381 tcgtacttat gggatgggta cagaaaaaaa gaaatttagg tggtcttgta tttgttgatt
    16441 taagagatac aagtggatta tgtcaaatag tttttgatac agatgtagat aaagaagctt
    16501 ttgaaaaagc tgaaaaatta ggggctgaat ttgtaatagc tgtaaaagga aaagtatgcg
    16561 aaagacaatc taaaaaccct aatatgccaa ctggtgatat agaaatattt gcaactgaac
    16621 ttagactttt aaacaagtca gaaactccgc ctatttatat aaaagatgat gatgatgttt
    16681 ctgaagcact aagattaaaa tatagatact tagatttaag aaaaccatct atgcaaagaa
    16741 atttaaaatt aagacataaa gtaatgaata ttacaagaaa ttacttatca aacaatagat
    16801 tttgcgaaat agaaacacca tttttaatag ctccaacacc agaaggagca agagattatc
    16861 tagtaccaag tagagttaat ccaggaaaat tttacgcatt accacaatca ccacaattat
    16921 ataaacaatt attgatggta agtggtatgg atagatattt ccaaatagtt aaatgcttta
    16981 gagatgaaga tttaagagca gataggcaac cagagtttac acaaatagac tgtgaaatgt
    17041 cttttgttga gcaagaagat gttatgagta tgattgaagg tttgcttgaa gcgatattta
    17101 aagaagtttt agatgtagaa ttggcacttc cacttcctaa gatgacttat gcagaagcta
    17161 tgtctaaata tggttcagat aaaccagata ctagatttgg atatgagtta acagatatat
    17221 ctgatgttgt ttgtaactgt ggatttaaag tgtttgctga tgctacacaa ccaggaaaaa
    17281 gtgttagagg tataaacgta aaaggcaaag ctgacgactt tactagaaaa caaatatcat
    17341 cactagaaga acatgctaag acatatagag caaaaggtct tgcttggatg aaagtaggac
    17401 aagaaggagt aacttctcca atagcaaaat tctttaatga agaagaaatg aacgctatac
    17461 ttacaagaat gaatgctgaa gtaggagatt tacttttatt tgtagctgat aaaaactcaa
    17521 tagtatttga tgctttagga caagttagac ttgaagtagc aaataggctt aatctattgg
    17581 ataaaaatgt atataactta ctatgggtaa ctgagttccc agtttttgaa gaagatgaag
    17641 aaacaggcac attctcagca atgcatcacc catttacatc acctatggat gaagatttag
    17701 acaagttaga agaaggtgat aagtcatctt taagagcgaa agcttatgat attgtattga
    17761 atggttatga aataggtgga ggaagtgtta gaatatcaaa ttctgatgtt caatcaagaa
    17821 tgtttaaagc acttggtttt acagaggaaa gagctaatga aaagtttggt tatttattag
    17881 aagcatttaa atatggtact cctcctcatg ctggtctagc ttttggtctt gatagacttg
    17941 ttatgttact tgcaggaact gataatataa gagaagttat tgcattccct aaaaatcaaa
    18001 atgctgtttg ccctatgaca aatgctccta cattggcaga agatgagcaa ttagaagaat
    18061 taagtataaa agttgatata aaagataatg aataatatgt agttgcaaga aactaaaatg
    18121 taaaaagtct ggatataaag tatatttata ttcagacttt ttttattaga attattttat
    18181 attttttctc tatatatttt cataaattat ctttgtattc tcagccaata taattaaaat
    18241 actatgttta aaaattttac ataaacttga ttgttttaga aactacttct gtaatgagta
    18301 cacgatttta attaaagaat atataacaaa tttgaaataa gtctaatata tgacttaata
    18361 gattaaatta aaataataaa tttggactat ttatctattt ataacttaaa ttatatcaaa
    18421 ttgataacaa actagatatt atactttttt gtagaataga attacaatta tataaagaaa
    18481 aattctatta atagtgaaaa aaaagtagaa aaaagtagaa attattcttt tataaagaaa
    18541 gggagggata atattgcaag agagagaaga attagtttta aatccagttc caaaagagga
    18601 aagagttgga tggttagctc cattgtttaa tatgcttggt tctaacatag ctatatctga
    18661 actaatggtt gggggaactt taattttagg aatgactctt tctaatatga ttattacatc
    18721 aattataggg aacttaatat tagttgcaat tattatgata caaggttata taggttacaa
    18781 agaagggtta aatacgtatg tattagctaa gggggcattt ggagagatag gaggaaagta
    18841 tcttatatct ctattacttg gtataactag ttttggatgg tttggtgtac aagcaggggt
    18901 tgcaggacta tcagtacaaa agatattccc aagtgtaaac ctaacattag ttacagttat
    18961 acttggatta tttatggttg tttttgcact gtatggcttt aaagctatgg ctaaatttaa
    19021 ttacttagtt ataccaccac ttatgatatt aatggtgtgg ggagttttta aagctttttc
    19081 tacttatgga gttgaagcta tttataatta tactcctcaa acaactatga gtatggttga
    19141 aggtcttaat attgtagtag gtcttgttat agttggtgca attatatcac ctgaccagtt
    19201 aagatatacg agacgagtaa aagacatttg gattatcagt tttttaggtc tagggattat
    19261 ttcattattc caacaagttg cagctggtgt aatgtctatg ggagcaccta cttgggatat
    19321 aacagaagta ttggctaatt taggttttgg atgggtagcg tttgttattt taatacttgc
    19381 atcttggtct acaaacgtat caaatgctta ttctggtgga ttagcattaa aaactatttt
    19441 tccaaatgta aaaagaaatg ttttgacttt agttgcaggt ctaataggta caataatagc
    19501 agctactggt ataatattta aatttcagtc atttttatct ttcttgggaa tcgcagttcc
    19561 tgcaatagca ggaattatgt ggtgtgagta ttattttata caaggaagaa cttataagca
    19621 tagagaagga ataaattgga ttgcagtaat aagttggtta ataggttttg cagcgtcgta
    19681 ttatagttca aaaataaatt tcttaatacc tccgataaat ggaattgtag tgagtatggt
    19741 tatttattat atattaatga attgttttgg aatcaaagat aaataaaggg ggcaattaca
    19801 tgggtcgtaa ggtgaaaata ggtataattc aacaacacag tgtacttgga aatgttaaaa
    19861 aaaatataga aaaagcagta gagatgatag atgacttagg aaaacaaggg gcagatataa
    19921 tttgtttacc agaactattt gctacaggat ataatttaga gtctttaggt ggagttaaaa
    19981 cattagaatt aataagagaa cataataagt acatagagga atcaatgtca gaagctgcta
    20041 aaagaaataa tgtatacctg atatctccat atggaacctt agaaaaaggg tctacacatg
    20101 tttataattc agcagttata tttgatagaa aaggtaagat tatgggagaa tactgtaaaa
    20161 atcatctgtg gtcattagaa gcagtatact ttaaaggagg ggaaaaagta gaggtatatg
    20221 atgctgattt tggtagattt ggtgtaatga tatgttatga tgcaggtttt ccagaagtat
    20281 ccagagaatt gacattaaaa ggttctgaaa taatatttat accatctgca tggagaatac
    20341 aagatgaaga tatgtgggat ttaaatgtat ctcaaagagc tttagagaac actgtatata
    20401 cagtaggtgt aaatttagta agtaatgact ctaatttaat actatttgga aagagtaaaa
    20461 tatgcaatcc tagaggtact gtaataactc aattagatac atacagggaa aaatatgtat
    20521 tatcagagat tgatttagat gaaataaaaa agtataggga agatatcccc tatttgaaag
    20581 acagaaaaag tagctataac atataattct atactataat acaagttcaa tataaaatga
    20641 taaaaagagg atgtatcaat attaagatta aatttattat actttgatat atcctcttta
    20701 atattatcaa ctttgattta aatattttta aaatagttga taagaaagtt tttgaacaac
    20761 aacacagctt tagattcata gttttcgcta aaccatgaaa gatttaaata tcttttaaat
    20821 tcaatatctt tgatatgtaa caacttaatc tcagggtctt gagataatcc ccatgatttt
    20881 ccacatataa atccaactcc ttgaagtgat tttataagag cataaattgt atatggtgaa
    20941 tcagactcaa atgctatttt gggtttgaaa ttagctgatt cgcacaggat atcaattacc
    21001 tctctataat tctcaccctt cgttataact ataaagtttt catctgaaac ttcgcttaga
    21061 tatacttcat cctttaatga taaaggatgg tttattgaaa ctcctaatag tatttcttcg
    21121 catgttaaag ttatgctatt ttctgagttt agctttgtaa atgaagaaga tatgtacaaa
    21181 tcaaaatcac tttttttata agatgatggc aaagtatgtg acacattaaa agtaatattg
    21241 ggatatagtt ttctgaaatt actcaaaagt gatggtaaca cattagccgc tgcaggagat
    21301 aatatcttta cttctcctga attttctaaa gaagtgtctt gtaactcctt ttttgaactt
    21361 tctactaaat ctaaaatgct atctactctt tttagaaaca atcttccata ctcatttaaa
    21421 acaatatatc ttccttttct gtcaaataac tgaactccaa gttctttttc taaggaagat
    21481 atagttttgc ttaaagctgg ctgtgctata tttaacttgt gtgatgcttt tgttatgtgc
    21541 tccattctag caacagtttg aaaatactta agatgcaata aatccatagt ataaaataca
    21601 cctcttttaa tatgacttga gttatatcaa ttttataatc aactccacat tatacattat
    21661 aatataaagt ttatataata aactacaata tattaaaaag ttatttaaat tgttatttat
    21721 attttgtaca taatctaatt aaaaaaagta actttaaatg attaactaag gaaatattgt
    21781 tacaaacttt agttatataa aaaattcatt tgatgagcaa agtattaatg tcaagtaaga
    21841 ataaaagctt attagataag aaaaataata ttttataata atgatgttac ttaaattatt
    21901 atgttatact attttaaata ggaaacattt agatactata attttagggg gagtcaagat
    21961 gaaattaact aaatcaatat catcaatgct gtgcttatct ctagttttaa gcttatcacc
    22021 agtagcatat gcaaatgaaa taagtagaac aacagttgag aatactttag taggtcagga
    22081 tagatatcaa actgctgttg aagtaagtaa aaaaggatgg agtagtgcaa atgaggctgt
    22141 agttgtaaat agtgaatcta ttgtagatgc attagctgta acaccatttg ctaaattaaa
    22201 aaatgctcct atattattga cagaaaaaaa taatctaaat tcacaaactg agaaagaatt
    22261 aaaaagatta ggagttaaaa aagtttatat aattggtcta tctagttctg tatcaaatga
    22321 tgtgcaaaaa cagttagaat ctaataattt aactactgat agagttggtg gtagtgatag
    22381 ataccaaaca gctttgagta tagctaaaaa aatagaagga ttaaaagata tatcagaaat
    22441 agctgtagta aatgggtaca caggtcttgc agatgcagtt agtatagctt ctgtagctgc
    22501 tactaatgga atggttatac ttccagtatc tgatgcatct ggtatatcta gctttaaaga
    22561 ttttatagaa tctaagaata taaataaatc atacataata ggctctacta atgctgtatc
    22621 agataaaata aaacaaagtt tacctaattc agaaagaata ggtggagcag atagaaatga
    22681 aactaatggt aaagtaatag aaaagtttta tacatctaat aaattaaaca atgtatttgt
    22741 ggctaaggat ggaatgaaaa atcaaaatca acttatagac gctctagcag taggagtact
    22801 agcatcaaaa gaaaattctc ctgtactaat cgtaggagaa caattaagtg caacacaaaa
    22861 gagtgtattt tcgaataaaa atgctacctc tataactcaa gttggtagtg gaggaaatga
    22921 aaatgcattt aaagaattaa aagatttaca ggcaaatagt aacaataaga gagtaatgta
    22981 tgtaactaat acagataagg taaatataag aaatgatgct acaatagaag cttctgttat
    23041 aggatatcta aataatggtg atgaagtaga agttttagat gtgttaaaaa ctggatgggt
    23101 aaaaataaaa tacaatgaag gtattggata tgttagtggg tcttatttga caaataataa
    23161 gcctgataat agtaatgaaa atataaaaat aaagtatgta aaagaaaaag atggtctaaa
    23221 tgttaggaaa ggaccaagta cagaagatga aaaaatgggt caactttcat atggaagcaa
    23281 agtagaaaca gtagaaatgt ttgctactgg atgggtaaaa ataaagtata atggtggata
    23341 tggttatgta agtaatgatt acttatctga tacaccagtt atttaattat aagtaacaat
    23401 aaaaaaactg ctttaatttg taaagcagtt tttttataaa aatttaagtc taataactat
    23461 ttctattttg ataccttaat cctgggattt attattatgg atattatcaa catacaaaca
    23521 ctccaaatcc agtgtctaat tccaaactta gatattaata aattcagtcc tgctatggta
    23581 aataagcagt atttaattac aattaaaagt gtatttatag aaagcccctt catagaaagt
    23641 atcctaaatc caataataga cattctaagt cctataaatg ccaataatat acctgcaata
    23701 tcctgaatta agtaatagta ttcaaatttc atattcaatc aactcttctc tgagcagtat
    23761 caaatatttc taactcttca atttcatcat ctgtgtatgt aagcatagta aaaccagtta
    23821 caccataaat aaatgaaatt ataggtgtaa tccaacttaa gaaacaatat ggaataaatt
    23881 ctagtgggct tacaccaaga gtctgagcac agaaaacagc atttgaattc catggtatta
    23941 atggaccacc aagtgtagct gtatcttcta taattctaga tagattttgt ggttttaatt
    24001 taaattcttt gtatattgga gacattagag ttccgacaaa tacagaagtg aacatcattg
    24061 atgaactaaa tgcatttgca aagtagctta ctataaaagt agacccaacc aatttagttc
    24121 ttgattttcc tattttagtt ataagaggtt gaagcagtac ttctaagaat ccagtttttt
    24181 ggagaatacc agcaataacg aaaactacaa atactagtaa aacggtttca gccatactca
    24241 ttattccacc acgatttaat agtttgtcgg catagacaaa tccagtatct atagtaaatc
    24301 ctgatagcat gtaatttaaa acatcaccta ttttttctcc ttcttgaaat actgctataa
    24361 taagtcccat gatagctgaa cttagtatag atataatggg tggcttttgt agcaataaaa
    24421 gtaataataa aaatattatt ggaatcattg ctactaaacc aatatgaaag tttgaattta
    24481 atacatcctt gatttgattt atttgaacat agtctatagt attatttgag tacttaaatc
    24541 caattactgt atacagaact atacatatta cgtatgcagg tcctgtggta taaaacatat
    24601 gcttcatatg tgtaattaca tctgtcttac aaactgctgc agctaagttt gtagaatctg
    24661 atagaggtga catcttatct ccaaagaaag caccagaaat gactgcacca gctgttaaac
    24721 caagaggaat gcccatacta gtaccaatac tcatcattgc tataccagaa gttccaagag
    24781 tcccccaaga tgtaccagta gcaacagaag ttaatgaaca tacgattaat gttgtaagca
    24841 gaaaatattt aggggttatt attgttagtc cactatatac tactgttggt attgtaccag
    24901 cagctatcca agctgctatt agtacaccaa cagaaagtat aattaagttt gattgaaagg
    24961 catctttacc aacttcaaat ccaaaagctt ctatttcatc attagtataa ccaagtttca
    25021 tggctgcagg aactactata agccatgaaa gtaaaaacat tgtagttata gaagcattaa
    25081 atacaactat accaactgat gttagggcta ttattgcaag cattactaac aaggaatatc
    25141 taaatgaagg tatttttctt tctgtattca ttttcatagt gcaaattctc cttaaatatt
    25201 tttagttaat tgcatttttt attcttataa gagcttcttc aagcatactt cttggacaag
    25261 ctaagtttat tctttgatac ccacttcctc caatgccaaa gctgtttcct tgatttagag
    25321 caactttacc tttttgtaca agtatacttt ctagttcctc atcacttaat ccaagtgcac
    25381 taaagtctac ccataataaa taagtacctt ctggttttct aactttaagt tttggcatat
    25441 tttcatttat atattttata gcaaaatcta tattagattc taaatattct aaaaatgatt
    25501 ctagccaaga ttcaccatta ttatatgaag cttcagttgc aactaagcta aagcaattat
    25561 ttctctttat atcaattctg gtaaaggcat catctaacaa tttatagtct ttttcatcag
    25621 gtagtattac atatgatgat tgaagaccag ctatattaaa agttttagtt ggagccatac
    25681 aagtaattgt atttttttca aattctttag aaatagatgc cataggaata tgcttatgtt
    25741 tttttaatat aatgtcacta tgtatttcat cagatatgat ttttacatta tgcttaagac
    25801 aaatatctcc tagttttttt aattcatctt ttgtccatac tctaccaact ggattatgag
    25861 gattacaaag tatgaataat tttacatctt taatcttgtt ttcaatgtct tcataatcca
    25921 ttatgtagtt tccattttct agtttttgta atgggtttat aattagttct ctattgttat
    25981 tttttacaac actattaaaa gggctgtaaa ctggttcttg tatcattatt ttatcatttg
    26041 cttttgtgag ttcatttatt aaaagactta tagctgggat aacacctgga ctataaatta
    26101 accactcact ttttattttc cagttatgtc tcctatatag ccagtttact atagattcat
    26161 tgtaagaatc tggtcttgtt gtgtagccat aaatctcttg ttctagtcta ttttttaagg
    26221 aatcaattat acaaggtgca gccttaaaat ccatgtcagc cacccacata ggaagtaaat
    26281 cattagttcc atactttttt tccatttctg accatttaga tgaaaaatta ttgcttctat
    26341 caacaatctc attaaaatta taattcattg taaatacctc cagtaatttt aattttatgt
    26401 taataatatt aagcaaacaa cgtgccaata ttgataataa aaaatattta ttcacaagtt
    26461 aatatttaat attaagtaat ttcagagcat agataagata aaaatattaa ttatacttaa
    26521 aactttgtgg aaaaggttat ttctaataaa tttttaaata tatgaaaatg taattaaata
    26581 ggttaaatag gtttaactgt ttaacttgtt agacctattt atatttttta gaaattctac
    26641 tccttttgat gttataattg aacctccacg accaacaagt atgtctacaa gcccaaagtc
    26701 ttgtagttct aaaagcatat ttctaatctg ttgttctgtc aaaaatctat tttcctctaa
    26761 agctatttta cataagcttt ttctacctat tctttctttt aaatcataag ccttttttaa
    26821 attatccaat ataaatatgt attcatctag tgacctttta aaattatagt cgtatttcat
    26881 gatgtttttg tctttgccaa tgttgaattg atactttttt atattatcac ttactttatt
    26941 acaaacggtt ctactataat ttgaatctat agtatccaat atatattcag gtaaatcaca
    27001 tatttctata atatcttttt ctaagtaaca gaagtattct cctaagtttc ttaattctct
    27061 tacatttcct tcccatctat acattttaaa gatttctttt acttcctcac ttagaataaa
    27121 attacatgga atatcatatt ttaatgaacc aaaaatttca aatatatcag caggtctttc
    27181 cctaagtgga tgtattttaa ggggaagaac attcaaccta aaatataaat ctcttctaaa
    27241 catattttta gatacaagtt cttttaaatt tctattagta gctgcaatta ttcttacatc
    27301 aatgtcaatg acattattag aaccaatacg tcgtacttgt ttttcttgta tgactctaag
    27361 taatttagat tgagaattta aatccatttc tccaatttcg tctaaaaata tagttccatt
    27421 gttggctaat tcaaataaac caattttccc acctttttta gcaccagtaa aagccccttc
    27481 atcatagcca aataattcac tttgcagtag attttcttga aaagtactac aatttactgc
    27541 gacaaaagga ccatcttttc tcctagaagc actatgaatg gattgagcaa ataattcttt
    27601 accagtacca ctttcaccaa ttataagtat agatgaattt gattgagcca ttttattagc
    27661 aatttttttt gtattaatag tttgtatact agaacctaat atatcatcaa atgtgtattt
    27721 actgatatta ccagagttta ctagttgtgc tcttaattta gcttgctttt tttctaattg
    27781 agaaaacttt gtcatcttta gtataaatcc atcaaataca tttaattgta tatgtttaat
    27841 ctctaaattt atatcaatat gatttatttt aatcaatttc tcaaaaaatg gagttttatt
    27901 ggtcaatatg ctttgaaaat tgatgtcttt tatgcaatca ccaacaaatg agtcaatcat
    27961 ttcatttgca tttatagaca aaatttttct agccatatga ttatagaatt gaattattcc
    28021 atcgttattt gtgcatataa ttccatcatc aattatagat agtaacaaat caaattgtct
    28081 ttcaaactta tttgcatcta acaataactc acctgtacta taacttgtag gaattatttt
    28141 ttctacgtat ttttttatta ggtcatcttt tattagatgt tttaatttgg tttttgtagc
    28201 aatttcaaca atacaactta aatctattat tctgtatttt aaatctataa cttcacaatt
    28261 tttaaactta ggcaagattt tttcgccagg agttaggatt acagcatctg tgggagtaaa
    28321 ctcaatctct ggatagcagg gcaggatatt tatattgtct attcctaatc tatgtattaa
    28381 agaaattgtt tctattgcca tatctttact taagttatat acataaataa ttttatcttt
    28441 ttctaatttg gatatcatat caatactgtt cttttcaaat gtcaacttgg gaacaatgat
    28501 ttgagcatca tagtgagata attttactat ttcatcatat tttaaataag cagataggag
    28561 tataagtttt tctttaaaaa actttaaatt tccctcttca aatgagtata aatttatctt
    28621 tagattatca cctaagaatt gtcttatttg attttcataa atttctccag cgtctttttt
    28681 taaacttaca atagctaatt ccatttgttt cattttaacc tctcatacaa atttgactta
    28741 ttttagatta cataataatt aaattagatt aaataatatt atttaattat tattataaat
    28801 ttattataga ctacacattg aagtaaaaga agtagctaaa attattcctt ttatttttgt
    28861 tttttgtatc tatttggtat aatagtatta gagcgtataa taatttaggc aaaatttttt
    28921 aaggaagact agaggagaat ataaaatgaa aaaatgtctt tactgtaata gggatataaa
    28981 gtcaccaaat aataaattag ctataaaata tgatgacaat atgaatatat atccatgtcg
    29041 tgcagaatgt aaggaaaaaa ttgaagaata tatagcaaaa aaacctacat ataagtttat
    29101 aaatatatta gaggttcttt taggtgtggg cggaatattc tgctttttga gtaaatggac
    29161 tattgcagcc caagttgtac ttggaattga tgcactggtt atatttttat tcccattggc
    29221 aggatttaag atgaatggaa agttaagtat ggaacaaact aagaatcaaa gtaggtctat
    29281 tgcaatatca attttggcat ttatagtaat aataactgta ttatatttta aacaagttgg
    29341 taagtagagc ataattgtat aagacatcat tagagtatga ggtgagttta tggaagaaag
    29401 aaaattagca ccaaacaatg agagggaagc tctcataaaa agattaaaaa gaatagaagg
    29461 tcaagttaag ggtatacaaa agatggtgga acaagaacgt tattgtgttg atatattggt
    29521 tcaaatatct gctataaggt ctgctataaa tagagtaggc acaattatct tagagaatca
    29581 tataaaagga tgtgtagcag aaagcattaa acatgatgat gctgataaaa ctgaagagat
    29641 gataaaagag cttatggata ctataaataa atttacaaaa taaggaggcg gttagttatg
    29701 aatcaacaag gatttattat ggaaattgtt gatgatagaa ctgcaaagtt aaaaatgcaa
    29761 agacattcag cttgtgctgc ttgtggaaaa tgtgctacta caaattcagc agagtcaaaa
    29821 gaaatattag tagaagtaga caacacaatt ggtgcaaaag ttggtgacca tgtagaagtg
    29881 agtatggata atatgaatgt attaaaagca gctgtaatgg cttatataat acctcttata
    29941 gcacttcttg taggaacaat agggacttat tatatattgg gggcaattgg aatgacaact
    30001 ggagttgaag ccataagtgg attagttgga atttgtctta caataatctg ttatttatac
    30061 ttaaagaaga atgacaaaaa atttagagac agtagagaat ttataccagt aataacaaga
    30121 atattaattg acctttaaga taattataat taaaaaatag caatgtactt tttaaataaa
    30181 tactcaatac gtatttgtag agtttaagta cattgctatt tttatatttt tattttgatt
    30241 ttctgtaagg aataaagttt tttctgattt ttaaaagatt caatgttctt acaaaagaag
    30301 ttacaactaa tacaccaagt gctattgcag cacttagaaa tagagcatct gtaccttttg
    30361 acatagccaa agaataattt ttctgaatca aagacaacat tgtattatat agcccaattc
    30421 ctggtattag aggaagaata cctggaatta cgaacacaat agctggttgc tttagttttc
    30481 ttgctaaagt ctcactgcac gctgagacca aagcagcagc gataaaacct gcaaaaactg
    30541 catttgtagt aaaattaaat aaataaacat atacaatcca accaattccg ccagttactc
    30601 cagctggaag aagtagatat agtggagcat taaagaaaac agcaaatcca gcagttgcaa
    30661 cacctgaaaa taaaaaatgc aaaatcatag acatatcagt cattagaaag gacctcctat
    30721 tctataccat gtatcaagga caaaaccaac tccagaagca attgcaataa taatcatagc
    30781 agcatcaaaa gcacgagaaa ttcctgatat taaattccct gatattaaat ctctaatagc
    30841 ttttataaaa gcaactcctg ggagtagtgg cattatagcg ccgactataa gcattttagg
    30901 gtcatctaaa atgcctattt caactagtag aactcctgaa agtgcaatta aaaaagaaga
    30961 tactaaacag gaaaatgcag atattgcact tatcttcatc gttttatcat aagtaattgc
    31021 agcaaagatt gctattataa acgtaagtat aaaatttaat acataattcc ctccaagcaa
    31081 acaagcaaaa caagcagatg caattcctgt acaagagtaa aataaccata aaggataagg
    31141 ttttacatct tggatttcat aaagacgtgc aatggcatta tcaatatcat actctttgtc
    31201 actaacaaat tctcgagaaa aactgtttaa taaagaaatc ttatttaagt ttatacctct
    31261 tgattgaatc gttttcataa acgaaaagcc atcaaatttc tcatctgaaa taattattac
    31321 tgtaggagtt gtaaaaatat ttacatgata aaaccctctt gacctgcata ttctaaggac
    31381 actgtcttca accctagatg tttcagctcc attttttatc atcagttccc ctacaaatag
    31441 agctagtttt agaatatttt tcttatattc aagttcctca ttttgattca taaatacacc
    31501 tccaaattaa aaaacgtaat attgaaatta tatcaaattt ttaagtaata ttccttaata
    31561 tctatataaa tatattatct tttttttgtt tcaaaatagt cacatttaaa ttatatccaa
    31621 ttaaaagaat tagacaatat tatttattat attttaactt aaaaataaag aaagtaacta
    31681 tgttaaatat ggaaaaatgg caaaacactt gactattaat tggtaaagga ctataataat
    31741 aaattatcat attgataaaa acgaaaatta tgaaatgtct gtaaaaataa aatttaaata
    31801 ataactagga ggagtaatat gtttgagaac ttgaaaaaag cggaccctga gatttatgaa
    31861 agtatgaaaa gagagttaaa aagacaacaa agaaatattg aattaatagc atctgaaaac
    31921 atagtatcag ttccagtaat ggaaactatg ggaagtcatc ttacaaataa gtatgcagaa
    31981 ggttactcag gcaaaagata ttatggtgga tgtgaataca tagatgaagt tgaaactctt
    32041 gcaatagata gaatcaaaaa aatatttgga gcagaacatg ctaatgttca acctcactct
    32101 ggagcaaatg caaatattgg tgtatatttt gctatgttaa aaccaggtga tgttgttatg
    32161 ggaatgaatt tatctcaagg tggacattta actcatggtg ctccagttaa tatttctggt
    32221 caatattata aattttatga atatggtata gataaagaca gtggacttat agattttgat
    32281 gaagttagaa agatagcaca tgaagtaaaa cctaaaatga tagttgcagg agcaagtgca
    32341 tatcctagag aaatagattt taaaaagttt agagagatag ctgatgaggt tggagcattg
    32401 cttatggtag atatggctca tatagcaggt cttgtggctg ctggtcttca ccaaaatcca
    32461 tgtgaagtgg ctgattttgt tacaacaaca actcacaaaa ctttaagagg acctcgtggg
    32521 ggtgttattc tttgtaaaga aaaatatgct aaagacatag acaaagcaat attccctggt
    32581 attcaaggtg gacctcttga acatataatt gcttctaagg cagtttgctt taaagaagct
    32641 ttaagtgatg agtttaaaga atatcaggta caagttgcta aaaatgcaaa agccttagct
    32701 gaagaactta ttaaaagaga ttttaaattg atttctggag gtacagataa tcatttaata
    32761 ctattagatt tgactaataa aaatataact ggtaaagcag cagaaaagag attggatgat
    32821 gcttatataa cagctaataa aaatacaatt ccatttgacc caaatggtgc tcttgttaca
    32881 agtggaataa gacttggtac tccagctgta actactagag gtatgaaaga agaagatatg
    32941 gcaataatcg ctgaggctat agacctatgt ttaacttatg atgaagaatc taaggctaga
    33001 acattggttg ttggtttaac tgaaaaatat cctttatatg aagaatataa tattatggat
    33061 taattataaa gaacaactaa ataaaataca tttaaataat tacaatgatt gtgtatgtat
    33121 ttgaatatat ttagatataa aaaaggtgtc tcaaaatgaa ctttttagtt tatgaggcac
    33181 ttttttgtat ggaatcgaac atatttgtat tatttaaata ataaaaaata tggttatctc
    33241 tatttttaga tggtctcttt gtatttttta attaaaactt taagatttct taagaattat
    33301 actaggtttt tctaaagatt taaagtctat acttataagt atagtaatca tatgaaaaga
    33361 aaagctttaa cgaggaggga atcttatgaa ggtattaatt cttacaggaa aatttggtat
    33421 gggtcattac tcagcatcaa attctttaag tgaagatata aaagcaaaat ttgataattc
    33481 agaaataata attaaagata tatttgagta cattatgcct aactattcag ataaaatgta
    33541 caagactttt tctattcttg taaatcgggg aagtagtctt tataatttat tttataaatg
    33601 tgctgaaaat ggaaagaaag atataaaatt tactttttca gattattttt taaataaatt
    33661 agatacatta cttcatgaag tacaaccaac agtagttatt tcaacttttc cattttgttc
    33721 tcaattagta tcaagatata aggaaaaata taactcaaat cttcctttaa taacatgtat
    33781 aactgatata agtagtcact cagaatggat tagtaaaaat acagactgtt atttagtagc
    33841 tagtaaatct actaaggaag aacttgtttt taaaggaata gatgaatcta agattaaagt
    33901 taatggtatt ccagtaaaaa aagaatttaa aagaatagaa catgtaaatc attcaactaa
    33961 aaaaaatatt cttataatgg gtggaggatt aggattactg cctaaatcag aacaatttta
    34021 caaagaatta aatagtttag aaggagtaaa aactactgta ataactggta ataataaaaa
    34081 aatgtactat aaactatatg gtagatatga aaatatagag gtagtaggtt acaccaatga
    34141 agtatataaa tatatgaaag attctgacct tattatttct aaaccaggtg gaataacact
    34201 atttgaaaca atttattcag aacttccaat attggcattt aatccatttt tacaacaaga
    34261 gatagataat gctagtttta tattaaataa tgaaattggg agaatacttg gtaaaaataa
    34321 aaaatactat gtagatgaga taaaagattt aatttatgat gatgctactc ttaaagaaat
    34381 gagcagtaac atgaaagaat taaaaaaaca atttgataat aataccttag agaatatttt
    34441 attttcactt gatgaacaag gagcgtgtag agaatgtatg tagtaggttt aattatcgtt
    34501 gttgcattga tttttttagt ccattcaatt atacctacat actataataa actattaaat
    34561 aaaaaggtat taaaaaatat ggctggagaa aatgaaattg cacttacatt tgatgatggt
    34621 ccagataaga gatatacaga aaaattacta gatgtgttaa aagaaaatga tatacaagct
    34681 atgttttttg tagtagcaaa gaatgctgaa aaagagcctg aaattataaa aagaatgttg
    34741 agagaaaatc atatagttgg tttacattca ttggaacaca gaaatgcatg gctttatagt
    34801 tatagttatg ttaaaaaaga ttttattgaa agtacaaata taatgaaaaa tttaggtgta
    34861 gatgtaaact actatcgtcc accatggggt catactaata tattttcaaa ttcatttgtt
    34921 aaaaaatata atctaaaaat gactttgtgg gatgtaatgg cagaagattg ggagaaagat
    34981 agtacagtag acattattat aaacaagtta atgagtagaa caaaagaaaa ttctataatt
    35041 tgtttacatg atgcaggtga aaattcaggt ggtgcagtag gtgcacctga gcgtactatt
    35101 gaagctttaa agatagctat tccaaaactt aaagccagtg gtttaaagtt cgtaacacca
    35161 gaaaggatgt agttatgata agtaaaactg aaaagaaaaa taaatgccta ggtagtgtag
    35221 cttttttagt tttactaatg ggcataacag gatattttgt ttttagaggg cagtcagttg
    35281 aatcattgat aaaatcatta aaaggtgcaa gccctatgtt tatactaatt ggatttgtaa
    35341 tgatgtttat atatgttgcc tgtgaaggta taaatatata cttaggtatg aaagctttaa
    35401 accaaaagac tactctttta aaatgtatgg gatatgcttt tattggattt tattttagtt
    35461 ctattacacc ttcagcatca ggtggtcaac cagcacaagt ttattatatg aaaaaagacg
    35521 atataaatat atcatattct tcacttatac tattagtcat tgttgttatt caccaagtag
    35581 ttatactggc atatagtgga ataatgttca ttatggaacg tgagtttata ttaaataatg
    35641 taagtggtat gaacatttta ctaatatatg gtgtaataac aaatgttgct cttgtcattg
    35701 gagtaattgc aattatattt tcaaaaaaac ttgtaaacaa ttttataata tcaataacaa
    35761 atttattagg taagttaaga ataataaaag atgttgaaag ttcaagaaaa gttataatat
    35821 ctcaaattga agagtatgtt aaaggtgctc aatatataaa gcagaatcca aaacttgtag
    35881 tccaaatttt agtcataact attgtacaaa taacagctat gtttttagtt cctttctttg
    35941 tatacaaagc ttttcatcta tcaacatata ctgtatttga gatattagcg atacaatcct
    36001 tgcttaatat tgctgtttct tcattaccat tgccaggggc tgttggagct tctgaaaata
    36061 gttttatgac attatttaag atatttttcc ctggtcactt attagttccg gcaatgttac
    36121 ttagtagggg gataagtttt tatgcatttg tagctataag tggattgata tgtatagtag
    36181 tacatgtaaa atcttctgaa aaagtaaaag cagtgaaaaa agttgcttat gtaagataat
    36241 attatataga ttatttttat taatatgtca atttgtgtgt atattttaat taagctttaa
    36301 acatgtttac aggagtagaa actattaaaa cgtgtgacat tgctaagctt ttgctaataa
    36361 agtataatat tttatatagt ttgaaatatt taagaaatat agcaaaaaaa ggagcttggt
    36421 gatgaataaa gagattccaa aaaaaatttt agtagctgat gataatcctg agattaggga
    36481 aatcgtagaa atacttttaa ctggtgaagg ttatgaagtt attatggcaa cgaatggaga
    36541 agaagctgta aacttagtag atagtacgat tgatttgatt attttggatg ttgtaatgcc
    36601 tgtaaaaaca ggatttgttg catgtaatga aattagagaa aaaacgacag caccaatatt
    36661 atttttaact gcaaaaactc aagactctga taaagttatt ggattttcag caggaggaga
    36721 tgactattta tcaaagcctt tttcatattc tgaactaatt tcaagggtta agtctctact
    36781 tagacgttat tatatatacc agggaaagga aaaggaaaga gagccaaata tattaaaaac
    36841 aaaagagtta tgtgtcaatt tagatactca agatgttaca ctaaatggag aacctgtgtt
    36901 tttgacaact atagaatata gtatattaat tcttatgttg aaaaatagaa aaaaagtttt
    36961 ttcgtctgaa aatttatatg aaactatttg ggatgagcag tatttttata cagcaaataa
    37021 tacaataatg gttcatatta gaaatttaag aaaaaagtta gaaaaagacc aaaaaaatcc
    37081 acaatatata aaaaccgcat ggggaaaggg gtattatatt gattaacaaa attaagccat
    37141 ctaagttggg agttatacta ttgatatatg tagtaatctc agctgcagtg gctttcattt
    37201 taaatatacc attttactct gctgttgaat ctatagtaaa agatgtatca gaagggaaag
    37261 tatattttaa aagagaagta aatcaactta tggataattt tcaaacttat gtgaataaca
    37321 atggtataag agcagatgat ggagatgata tagcaaaatg gaatagtgat aattggtttg
    37381 tttctatgaa gatatataaa ggaaataagg ttttttatga tacattatac tatcctaatg
    37441 aagtacctga taagagtgag gaaaatgagt tttatagcag tcccatggct agaaactatg
    37501 agatacaatt ttctgatatt aaagctaata tagttgtagt agctttattt agatttagat
    37561 ttcaaaattt tatagaagca atttctatta catttatggc acttacattt attataacat
    37621 ttttactgtt gtttagtaga aagataaagt acctaaggaa aatagaaatg ggtataaaga
    37681 tagtagagag tggcagttta aagtatagaa tcccagtaaa aggtaatgat gaattatcat
    37741 cacttgcatc tagtattaat gagatgagtc atacattgga gaatcaactt ataaaagaaa
    37801 gggagatgaa gaataaaaat aaagatatag taacttcgat atcacatgat gttagaactc
    37861 cattaacgtc agtaatttgt tatttagatt tgattaaaga ccataaatac aatagtcctg
    37921 agcaattgga acaatacata aaaaatgtaa ggtctaaagc atatcaaata aaagatttaa
    37981 cagatgacct ttttacgcat tttgttaatt ctggagagga agtttcaaaa gggtatgaaa
    38041 aaataaatgc taatgaattt atttttcaat tacttttaga tagttcatat acattggagg
    38101 agaaaggatt tcatataaca atagaaaatg aactttataa ccaatatcat atttatgtag
    38161 atgttacaca atttagaagg atatttgata atttatgttc taatataata aaatatgcta
    38221 ggaaagataa gcctatagta tttttaatta aagtagagga ttctaaatta ctaattatac
    38281 aaaaaaatag agtaagtaat ttttctaaga atgtagaaag ttttggaatt ggtataaaga
    38341 attgtgagaa aatagttgca tatcataatg gaagcataaa tgtaaattca gatgataaag
    38401 aatttgctat tgaaatatct attccagcaa aagaatcata aaaatttaaa ttatatattg
    38461 tgtaattgct attatatatt gtgtaattgc ttatgtaaaa ttctatgaag caggaagcat
    38521 gtgactttag ttatgggatg ttcaatattg tgtacctcta ggcaagtaac aagtttactt
    38581 ataagaccat ataatattat tatcttaaaa aaaggggaca taataatatg gttttgacag
    38641 gagcacatta tatttacatt ctatttatgg taattatatt aattactatg attatgaaaa
    38701 aggatacaat agtaccatgt atattaggtg ttttttttat ggggttgttc tttgaaaaaa
    38761 acatttttgg tgctataaca gcagtgttta actcttttat tatatcttta aatgagttgg
    38821 gtccaattat cttgattata gctattatgg ttgcattatc taaagcccta gaagccaata
    38881 atgctataca gtatatggtg agaccatttt cgagagttat aaaaaattct aatacagcat
    38941 tttttgtaac tggatttgtt atgttagttc tttcttggtt tttctggcca actccagctg
    39001 ttgccttagt tggagctgta tttttacctg ttgctatgag agctgggcta ccagcaattg
    39061 gtgttgcagt agcattaaat ttatttggtc atggtcttgc cttatctaca gactttgtta
    39121 ttcaaggagc tccaagtata acagctggtg cagcaggtgt tgcagtatca tatgttataa
    39181 atgatggtat gattttgttt tgggtgatgg gaatcgtaac catatctatg gcattttata
    39241 cattaaaaag agatattaac aaaggaatgt ttagagaaga actaaaaggt tttgaaagtg
    39301 aagaagtaga agagtttaat ggaaaatcta aaatagcaac tattttagta gctctgggat
    39361 ttcttgctga tataattgct atgtatatat ttgacctaaa aggaggagat gcatcagctc
    39421 ttttgggtgg aacagcagta tttttaataa taattataaa tgttataaat tttggcaaag
    39481 atagtcttga aaatgtatgt gagaatataa ttgatggttt tgtgtttggg ataaaaatat
    39541 ttggagcaat tataccaata gcagcatttt tctatatggg tgaagttgca ccattgacag
    39601 gtgtatttgg aaaagtatta gcaccaggtt cacaaggttt attatcagat ataggcatag
    39661 ctctttctca aacaatacca cttaataaat ttgccgtatc aggtatagaa actgtagtgg
    39721 gagcaataac tgggcttgat ggttctggat tttctgggat ttcattagtt ggttcacttg
    39781 cctctgtatt tggaactgct ataaatgcaa gtgttggtgc actagctgca ttaggacaaa
    39841 tcagtggtat atgggtaggt ggaggctgtc tagttccttg gggtcttatt tcagcagcgg
    39901 caatttgtgg agttagccca atagaattgg caaagcgaaa ctttgtccca gttataaccg
    39961 gattggttgt aacaaccata gtagcaatgt ttattattta ataaatcgaa taaatcttta
    40021 attgtataaa ttaaaaatag atgtgtagct ataatttatt ataattgttt tactaattct
    40081 aagccataca tctattttta ttgatatttt tattagtatt ctttaataaa ataatatttt
    40141 tcattatact atacataaca tctaaatata acatctaaaa tactgttatc tatatttaat
    40201 atcttgccaa attttttgat gttttattgt cctgtcccac caacatatat aagctatcac
    40261 aagtttttac ctatactatc accaaacaaa aattctaatt ttaatttatt attttataac
    40321 ctatattata ttaactatat tagtttgtag actttagatg taattataaa tattaatact
    40381 ccaagagttc aaattcatat cctagttttc ttgcatttga tataaaatca tttaaaattt
    40441 ctgtactagt tttggaaact gcatgtagta acaagataga accatcatgt agattatcca
    40501 ttattttttg cgttgcttct tcatgtgatg gttgtttatc agtatcccag tctctgtatg
    40561 caaaactcca aaatacagtc ttgtatccta aatttttagt cattgccaag cttttttctg
    40621 agtattttcc cataggaggt ctaaaaaatt taaccatatc tttcccagtt acatctttat
    40681 ataacttttc aacatcatat aattcgtcat taaagttttt tagattgctt gtttttgttg
    40741 gcatagatgg atgggtttta ctatgatttc caactatatg tccctcagaa accattcttt
    40801 ttactaaatc tttattttct tttatatatg gagttgtaac aaaaaaaact gctttaacct
    40861 ggttttgttt tagagtgtcg agtatctttg tagtgtatcc attttcataa ccttcatcaa
    40921 atgtaagata tagtgttttt tgaccatctt ttgtaggtcc attgtatagg gcatcatagt
    40981 cagaaaattt aaattcaatg tccgtattta cttctggtgt tttatgctta ttgtttggta
    41041 tataaaacca atcaagagta gtgttatcta aagaagatac atctaattta ttatcatcat
    41101 tattagtagt ggcttttgat ggtttatctg ttccgtctga aactattaca ttggaagtat
    41161 ctttaccact atctattttt tccttatctt cttgtaactg tgtttcctta ttttgatttt
    41221 cgttttgatt gttttgtgaa tttgaacatc caacaataaa aaaaatagaa atagaaagta
    41281 gtgttaaata atgcaatact tttctaaaca ttttgaagct cctttctaaa ttaataataa
    41341 ttgcatataa taataattat atgattaatt acaattgcat atagtattat tataattgga
    41401 aattactatt aataatagtt atatctttaa aaataaagtc acaatagtat gacaaagggt
    41461 gaataatcaa taaatttaaa aaaaaatgaa aaaaatagtt gaccatatta tgagaagatg
    41521 ttattataat aaatgtgctc aacaagaagt aacaaaataa caagcacaaa gaagttaatt
    41581 gaat
//
LOCUS       DAMKNB010000031        38308 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.033, whole genome shotgun sequence.
ACCESSION   DAMKNB010000031 DAMKNB010000000
VERSION     DAMKNB010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 38308)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38308)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38308
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.033"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            165..1316
                     /locus_tag="PC494_001794"
     CDS             165..1316
                     /locus_tag="PC494_001794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004452985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDF3912296.1"
                     /translation="MELRPRSAKLEEFDKVIELINYVFRISRNHKPTMMEEFPLLLSK
                     NNIENMIIISEDDKVVSDVNYLIQDVSIQGNRLKVAAIGGVCTHPDYEKRGYSSKILD
                     KVEEKMFYDGVDIVIISGTRSLYSRRNCSLVKSFYKYTIKPEDVKIAYEIVEFDETNF
                     EKDNDLDKMIELYNQNSTRFIRTRDEFQKLLHAATIAWGPIGYKKVFIKENNNIIGYL
                     IIRTIKKEDSTVGEVAEIGLNSVNVENILKYVANKFGLESLNYKVHVKNLKDQLKCNG
                     TKSLDYQQGTMKIINFTKLCDSLRSYFSQYVDFELLKYMEFKQVENKYIIKYKEEELV
                     IENLDKLNKLFFEKNEEQYNEFKHLKNIYEFATKAFPVDFPWTANLNYQ"
     gene            1434..2072
                     /locus_tag="PC494_001795"
     CDS             1434..2072
                     /locus_tag="PC494_001795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423639.1"
                     /note="Presence of a B(12) (cobalamin)-binding domain
                     implies dependence on cobalamin itself, in one of its
                     several forms, or in some unusual lineages, dependence on
                     a cobalamin-like analog; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalamin-dependent protein"
                     /protein_id="HDF3912297.1"
                     /translation="MDILDDIAECILNMGVDNIENLVKIAIDKNIDVEDIYEYGLNKG
                     MIGALDKFENKEYYLSEVIVCTDALNKGINLLKGTGKVKKKSKGVILMSVVEGDTHEI
                     GKNIVKVMVEATGYKVIDLGVNRKSEDIIEEAIKNNVDIIGLSSMMTTTMENMKSVID
                     ELNMIEIDKRPKVIIGGGPVSMEFAEEIGADGYSSNAPKAVKLINKLIGGEV"
     gene            2073..3095
                     /locus_tag="PC494_001796"
     CDS             2073..3095
                     /locus_tag="PC494_001796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase"
                     /protein_id="HDF3912298.1"
                     /translation="MFSDMTLLQYINSEDRGFFLPDMGTNGLFLINKKAYEVYDSVDL
                     QLELAKTMDKYFESDFIYSFCDGITFCETLGLDTLRPDYDFPSVLTHTITDRDKLRKL
                     DVPDPYTSGRMPLNIESLSVISKSIKKPLYESIQGPFTLAGQLAGATQLLRCIITDKK
                     FVEELLEFTTELVRRYAVAANKAGAKYISIAEPTSVTLSKDRFDEFIVKNLNKIYNEL
                     DCWKGMHICGDTRELLDNMLSCNIDAVSLDQILDYEEIAPMIPRDIVLIGNLDPIKLL
                     GRSKPDKIRRETLKLLKKMRRYDNFLCDFGCNCLNTTPVENLQAAIKAGRISYKELDR
                     IDIDEL"
     gene            3085..3705
                     /locus_tag="PC494_001797"
     CDS             3085..3705
                     /locus_tag="PC494_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3912299.1"
                     /translation="MNYNSNKNKYLLKDINLDDIFIDKNIVLKFLGYGNRKAPDTISK
                     IVEREIRNINDILDIKIYISEVDINKTPKECKKAFAVLYTIGDKIDFKMNDYMENCNM
                     MAGLALDKVGIVCLDCINEKIKMYLKGKYDSLKISHEIYPGDKDFEVERQKDIYNYVK
                     NKYNSIEIEINDYHQLSPIKSVAMLILMGDEENLESRCSKCPRKCF"
     gene            complement(3829..4515)
                     /locus_tag="PC494_001798"
     CDS             complement(3829..4515)
                     /locus_tag="PC494_001798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HDF3912300.1"
                     /translation="MKTYKFIFFDADDTLFDFKKSESHAFKKLLSEFDLEFNFENYIE
                     SYRNISDKLWLDLEKNIITLNELKLLRFELFANKISLDVDSETLSKMYLNFLGECTFL
                     IPGAIDILQYLKKKYTIVIITNGISAVQKKRLENSKIKEYIDGMVVSEELKISKPNPE
                     IFKYALKKFNCHDKSSALIIGDSLTSDILGGINSGIDTCWLNSNNSINYTNHIPTYEI
                     NTLIELKKLL"
     gene            complement(4529..5074)
                     /locus_tag="PC494_001799"
     CDS             complement(4529..5074)
                     /locus_tag="PC494_001799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF3912301.1"
                     /translation="MNDLNLGEKIAEVRKKQNLSIRDLAKLADVTPSLLSQIERGLAN
                     PSVNSLKSIASSLNVPLFTFFVSEVDKKNLIVRHDNRKKVILPGSKEVIYEILIPDSS
                     GNLEFAIMDLAPNTSSCVDRITHNGDEIAYVLEGEVKLFMDDDEFTLSKGDSVKVPLG
                     TKHKWQNDSNSESKVIFAVIL"
     gene            5302..6549
                     /locus_tag="PC494_001800"
     CDS             5302..6549
                     /locus_tag="PC494_001800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntP family permease"
                     /protein_id="HDF3912302.1"
                     /translation="MQITTFGAIFGLLIAIILIIKKFQAVYSLMLGAFIGGLVGGANI
                     TQTVDFMANGAMNISPSILRALASGVLAGSLIKTGAVDKISEQIVKIFGEKRALFSIA
                     ISTMVLAGVGVNLDVSIITVAPIGLYIGRKLNYSKLSILLAMLGGGKAGNIISPNPNT
                     IAVADNFSVNLSSVMMANIIPAIIGVVITVILASILINKGNKVQSYEILEQREDLPSL
                     FKSLCGPIIAIFLLFLGNVSPIVIDPMIALPIGGIVTLIVTGNLNNSREYLAFGLSKM
                     QGVCILLLGTGTIAGIIQMSELQQSTIGALQFLNMPQFLLAPVSGILMSLATASSTAG
                     ATIASSTFHDAIINGGLSPISGASIVNAGSSVFEQLPHGSLFHTSAGSINMDIGERFK
                     LIPYEALIGIVMTIISTSIQLVL"
     gene            6636..8630
                     /locus_tag="PC494_001801"
     CDS             6636..8630
                     /locus_tag="PC494_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HDF3912303.1"
                     /translation="MNKKKIVIIGIIYSFLVVFSLTNMYVNMEYNLNVFEYIKKSLPF
                     TEEEKKWLEKHKNLIYSSDQSSPPLRYKGKEDGQYKGIIVDLINSLSIQIGRDFYFKP
                     NNWWKESFVNSIDDSIKFFDLIPSKERANKFIFTDPIYTLSANILKDKKSQDINSYMD
                     LKGKTVAIPEGDYSINFLKQKIQDINILLTPDIKTGVNHLMSGKVDAVVGDEPVLRYY
                     INNYGLSNKYSVLSNPIYTKKAVLAVPKQYEELVSILNKGIFKLQKNGVYKDLKKKWY
                     STYNEVDDILYERGIVPSIYLFIGIILISIYVFYSYTYLLKIEIKRKTEQVIENKKTL
                     EATFNSITDIIMLVDENNNIVESNKVLYDFMGEMSYKIADLISMIKGVIENTFSENTN
                     KTSEIEIHNKILKINTFPVEYKKNNTEYIVVLIKDITNDKIVEAKLLRENKMISIGQL
                     ASGVAHEIRNPLGIIRNNCYLLKDNVTMEEVNDCVKSIESNVDRASNIITNLLNFARI
                     SDDNLEHINIRNFIENIVKLQYKMLQLKNVEIKIDCEHNLVCYINGESLKHVFINLIS
                     NSIDAIHQDGKIIIYCYEKNYCLFIDFKDNGEGIKEDALKDIFNPFYTTKPIGEGTGL
                     GLYITYNEIKKNNGDISVESKLGVGTCFHIKIPLNKEVTI"
     gene            8630..9952
                     /locus_tag="PC494_001802"
     CDS             8630..9952
                     /locus_tag="PC494_001802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-54-dependent Fis family transcriptional
                     regulator"
                     /protein_id="HDF3912304.1"
                     /translation="MKILLVDDELEYGVVMKKILQKKGYLVDIALSGEEAINIIKKDK
                     NYDLVLSDVMMKNMDGVQLLDRIKSINRDIEVILVTGYGSIENAVDAMKRGALSYFIK
                     SNPIENLLEEVEKVKASKISVSVQKNNLEFTLESKNRDFNNIIKIAKKAACKDVNILI
                     LGESGVGKDILARYIHSISPRKNEIFVPVNCCSFSENLLESELFGHEKGSFTGAVDSR
                     KGRFELSNKGTLFLDEIGDIPLNVQVKLLRTLEDKSIERIGSNKSIKVDFRLICAMNK
                     EPKVEISNGNIREDFFYRISTITITIPPLRKRREDLTTLIEFFLNKYQIEHDKKIHSI
                     DKEVKDFLLNYNYPGNIRELKNIINRLVVLSEEGNLSKDNLNLISNNVYIDDKISIRP
                     LREIRKEFECEYIEKVLSLCGNNISNTAKKLEISRRQLTNKISEYNIK"
     gene            10231..11517
                     /locus_tag="PC494_001803"
     CDS             10231..11517
                     /locus_tag="PC494_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006807454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine/sarcosine/betaine reductase component B
                     subunit"
                     /protein_id="HDF3912305.1"
                     /translation="MKLELGNIFIKNVEFGEKTEVKDGVLYISSEEIEKIVLEDERIV
                     SVNVELARPGESIRIAPVKDVIEPRVKIGDESKIFPGIINKVKTVGSGRTHVLLGACV
                     VTCGNIVGFQEGVIDMSGPTAKYTPFSKTNNICIVIKAKDGIDTHDYEEAARIAGLKI
                     GAYVGEAGREVEPDEVIVYETKPLLKQVKEYPDLPTVAYVHMLQSQGLLHDTYYYGVD
                     AKQIVPTFMYPTEIMDGAIISGNCVAPCDKVTTFHHLNNPVIHDLYKRHGKDLNFIGV
                     ILTNENVFLVDKERSSDMVAKLIEFLGVDGVLVTEEGYGNPDTDLMMNCRKCSEVGAN
                     VVLITDEFPGKDGKSQSIADATKEADAVVSCGQGNLVVHFPAMEKIIGTLDYVEMMIG
                     GYKGCLNEDGSMDAELQIIIASTIANGYNHLTARYY"
     gene            11603..12910
                     /gene="grdB"
                     /locus_tag="PC494_001804"
     CDS             11603..12910
                     /gene="grdB"
                     /locus_tag="PC494_001804"
                     /EC_number="1.21.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012158817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_except=(pos:12650..12652,aa:Sec)
                     /transl_table=11
                     /product="glycine reductase complex selenoprotein B"
                     /protein_id="HDF3912306.1"
                     /translation="MSKIRVVHYINNFFAGIGGEEKADIPPEKRAGVVGPGIAFQSQF
                     NDDAEIISTVICGDTYFGENIESATQELLKMIKEESPDLFIAGPAFNAGRYGVACGTI
                     CKAVEEELNIPVITGMYKENPGVDMFKLDLHIVSTGNSAASLRKVVPIMTKLGLKLVR
                     GEEIGPPEEEGYIMRGIRKNFFHELRGSERAIDMLVKKMKGESFETEYPMPEFDRVTP
                     MKPVKDLSKIKLALVTSGGIVPIDNPDKIESSSATKYGIYDLTDMDSMSNKEFTTIHG
                     GYDRAYVLENPNLVVPLDVVRELEKEGVIGELVDYFITTTGTGTSVGNSKRFGEEFSK
                     KLLEDDVDAVILTSTUGTCTRCGATMVKEIERAGIAVVHICTVVPISLTIGANRIVPA
                     VGIPYPLGNPMLGEEESKKIRKNIVLKALNALTEDIEEQTVFE"
     gene            13188..13919
                     /locus_tag="PC494_001805"
     CDS             13188..13919
                     /locus_tag="PC494_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF3912307.1"
                     /translation="MIRKKVYILISIAICDDESYMLNHLKENIELYMKQKNLLYNIEL
                     FNKVEDLLCNHEKFNIVFLDIQMEEINGMQAARKLRSYGNECFIIFVTVLNEFVFDAF
                     EVDAINYLIKPLSNEKLYKTLDKIVTKLDDNESNYITIQKGYSYWKLKLADILYCEVI
                     KRKIYVHLKKETVDYYETIENLERSLPTNFFRCHRSYIINLQYVYGYENGNAVMESGD
                     RIPVSRLRQQIFSKVMLEFMKNRRI"
     gene            13921..15279
                     /locus_tag="PC494_001806"
     CDS             13921..15279
                     /locus_tag="PC494_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HDF3912308.1"
                     /translation="MINLFSSDLFLKYSFLFSFIVYRILMVIVQYYFLISFTNVNSKF
                     WCFILYSIISIFLIIINTYFNLYNLFSSQILFFLMTFLFVKYIIKQSTVLSIVSTLLV
                     YLIEQLVYGFTAPLNYLIFTSDINTDIYKFDINMGLSSLITIIIAGFIYWYSSKKFNI
                     KVMNFDKYIAILMIPLLLIILFMQSFEYSSNINIDTSLGIVKLLLNTSITEEIQAFLF
                     SIIGTICVFFSLFTFKKLIQALEDDKERAIMNQQIHAQKNYIEEAKSRLSQTISFRHD
                     FNNHLAIVNGLLKKDQILKAQDYLNKLEKVTSDLSFSCNTQNIVIDALFNNKLSIAKQ
                     LGIEVDCEVIIPQSTNMNDFDLCIVFANAIDNAIKACRVVDKQNRYLKLSTKLEGGFF
                     MIEIKNSYNPINNYTSGSGIGLLNIKEIAKKYQGAISIDKTSDYFQINVLLVISLHCA
                     SI"
     gene            15318..15803
                     /locus_tag="PC494_001807"
     CDS             15318..15803
                     /locus_tag="PC494_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3912309.1"
                     /translation="MYLNRESLIYRNEEVTKMKVGNINGQAPITNGLDSCQSEVQGLE
                     QKKKSLQDEIEKVRSDKSIDGETAKLKIEALKKEMEEIENKIQELKGNKAKKTNKEEN
                     NVSEVNNNLLERKKEPSNNENVKQLYDVFERSNVDEQWDNTYRVLQDDKNLKVKFNRP
                     I"
     gene            complement(16457..16681)
                     /locus_tag="PC494_001808"
     CDS             complement(16457..16681)
                     /locus_tag="PC494_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HDF3912310.1"
                     /translation="MTVYNLKLGQKGIIDNIAGNEKLMKRLLALGLIDGTEVEVKKIA
                     PLNDPIVIRFRGFDLAIRKSDAKNINLKNN"
     gene            complement(16778..18031)
                     /locus_tag="PC494_001809"
     CDS             complement(16778..18031)
                     /locus_tag="PC494_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:glutamate symporter"
                     /protein_id="HDF3912311.1"
                     /translation="MITLSFDIVQTLTLSIFFFLIGNLLKNKVNFLNNFCIPAPVIGG
                     LLFCFLNLFFKYFNIADISISGNLMPNFITFFFTTIGLEISINLIKKGGSVLFRYWIL
                     CGVLAFCQNILAITISKIIKLEPLLGLMCGNVSMEGGHGYSAAFGLTIENLGIEGAVG
                     VGLSAATIGLIMGGILGCPVAKFLINKYKLKPSSNIDLSIPRYNRNLKRFGSKFFRNK
                     NRIKNNNFSETITPSVFLEQVLLIFICINTGEIISRCFYITFNILLPSVVTCMFSAVI
                     FRNLNDKINILELNFKLIDFLKELSLGIFLTLSLMNIDLFELSTLLPPILLIVTFQVI
                     FIILFSIFICFRVLGKDFDSAIIISGLIGHGIGATPNALANMSSLTQKYGDSPKAFLV
                     VPLVSGFLLDAISIPCILFFINILT"
     gene            18291..19280
                     /locus_tag="PC494_001810"
     CDS             18291..19280
                     /locus_tag="PC494_001810"
                     /EC_number="3.5.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosine deaminase"
                     /protein_id="HDF3912312.1"
                     /translation="MFENLPKIDLHCHLDGSVRVETMLDIAIKEKIDLPSNNMDEIKK
                     LAKVSFNCTSLDEYLEKFDLPLKVMQSKENLKRITFELLEDASRENVKYIEIRFAPLL
                     HTQKGMSVKNIIEGIIEGIREAESIYDIKGNLILGCMRTMTSKEALLVIEEGKSFVNK
                     GVVAVDLCGPEKEGFCKEYKDVFKLAREYGYKVTIHAGEAASGENVLDAINILKADRI
                     GHGVKIKDHKKAYNLVKDKKILLELCPTSNVQTKTVDSYEAHPFYTFYKDNLHVSINT
                     DNRTVSDINLSSELNVIFDTFKLGLEDYKIIYRNAVEASFADKETKEYLNSLI"
     gene            19352..20092
                     /locus_tag="PC494_001811"
     CDS             19352..20092
                     /locus_tag="PC494_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EcsC family protein"
                     /protein_id="HDF3912313.1"
                     /translation="MKDYEDVVYIKLVKKELEEWKKNILKKPSIFDKASKGIQNKFNG
                     VLPDKYHEIITSSIKVMTKTVLFGYKYATKPPLRNMSLEEREKLVLEKAKTYKTTAMI
                     EGAGTGAGGILLGLSDFPLLLGIKVKFLYDVASIYGYDVKDYRERIYILNILQLAFSS
                     QQHINKTFKLMNNWDEYVNSLPEDINDFDWRTFQQEYRDYLDLAKFLQLMPGIGAFVG
                     FYVNGKLIDKLCETAVSAYRLRIRELKL"
     gene            20308..21459
                     /locus_tag="PC494_001812"
     CDS             20308..21459
                     /locus_tag="PC494_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxyacyl-CoA dehydratase"
                     /protein_id="HDF3912314.1"
                     /translation="MTNLPKQFDSFNEARQKGFINAKELKESGKKMVGVFCTFTPVEI
                     PMAAGATVVGVCGVSEEPIPDAERVLPRNLCPLIKSSYGHAITDTCPYFYFSDLLIGE
                     TTCDGKKKMYEELAKVKPTYVMHLPNTSKGEFAYKLWKDEMIRLKEEVEKSLGVTITE
                     EDIRTAIKDKNEERELLKEFYALGKLQPSALTGLELHNVLYQAGFKFDRAELKHSLRK
                     VIDDMKERYEKGECPVQKDKPRILITGSPIGGISEKIVKTLEDAGASVVAYELCGAIR
                     SNDLLVDEEIEDVYDALTQKYINIGCSCMMNNDNRIELLDRIIDEYNVDAVIDVVLQA
                     CHTFNIESYRIREFVTKEKNKPFMSLETDYSKSDTEQLRTRFEAFVEML"
     gene            21484..22239
                     /locus_tag="PC494_001813"
     CDS             21484..22239
                     /locus_tag="PC494_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxyglutaryl-CoA dehydratase"
                     /protein_id="HDF3912315.1"
                     /translation="MFSIGVDSGSVATKGVLFDGEKIIKKIIIPTGWSPKSTSKQVYE
                     LLSSEIDKKDIKKVVGTGYGRGVMDFADKKVTEITCHTRGIYFLNKNIRTILDVGGQD
                     SKVINLDRDGNVFNFIMNDKCAAGTGRFLEITSNLLGSDIESIDTLAKGYEPVNISSM
                     CTVFAESEIVSLLAQNISTGEVAAGILKSIANKSTSMLARGEVIDEVAFTGGLAKSKE
                     LVKMIEEILGKKIFIAEDTQIIGALGAAVIGFR"
     gene            22431..24818
                     /locus_tag="PC494_001814"
     CDS             22431..24818
                     /locus_tag="PC494_001814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding cysteine protease Cwp13"
                     /protein_id="HDF3912316.1"
                     /translation="MKKFTSKKVTRFVALFLISILVMSTIPVSADNSNTLNQIKKAEY
                     SETYKQYLNDAKNGCTEKYNGIIPNPYQLEGTQIQSKGRTAPTSYDPRKLGLMTSIKN
                     QEDLGICWDFAAMATLESFLKLNNYGDYDLSEEHLRWWASDGEYGWSVNDMNGALNYE
                     AMGYLTSWSGPKLEKDIPYNGRVSKAQGAKKPTNMNTAPTVFNVTDAVCVSNDINSTK
                     NAILQYGAVTSGYYEDIKYQSDDQNSYYCPTKSFNTNHAISIVGWDDNYSKDNFNANI
                     RPSKNGAWLIKNSWGDYNSEGGYFWISYEDKTLMSDIDNFSIKGGKKPNDDEKMYQHD
                     YASIVPLISKKITAANVFDFNRGDETLKSVMFLTESIGAKYEVYYAPVVNGIPQENNM
                     KKLKEGTAQYSGYITVPIDSFDIPEGKGAIVVSIEGKNGESTIGSESNVPGYDTFKAK
                     ANLGESYIIDNTGKFFDINRDSNFYPCNFTIKAVTEKSSGESIPNESLIGSDRYETAI
                     KVSQNGFNSSENVVLVNGSSIVDALAATPFTSAINSPILLTQKEALNSKTKAEIQRLG
                     AKKVYLIGGENSISKEIEQQLKSLNISIERISGSDRYKTSLLLAQKLNGIKNVSQIAV
                     VNGVKGLADAISVGAAAAENNIPIILANEKSELQGADEFLNSLNIEKSYIIGGTASLS
                     NNLESKLKNPTRLSGSSRDETNSKIIDNFYKKDTLKNAFVVKNGIKNQNDLIDGLAVG
                     PLGAKTGSPVILVGDKLADSQKEVLKNKTLEKVTQVGGGANKNAFKELVKLKSAK"
     gene            complement(25049..25282)
                     /locus_tag="PC494_001815"
     CDS             complement(25049..25282)
                     /locus_tag="PC494_001815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase"
                     /protein_id="HDF3912317.1"
                     /translation="MATTTKNRFYDYVQENLNKYVEVHSYFSSCPLYGEIIEADSLSI
                     TLCSRYIDESNPTLNETYTLYLPLSSIISIRTL"
     gene            25571..26161
                     /locus_tag="PC494_001816"
     CDS             25571..26161
                     /locus_tag="PC494_001816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDF3912318.1"
                     /translation="MPKSYSDKEREYIIKRLKEEARLCMEQYGIRKTTVDELVKRVKI
                     PKGTFYLFFQSKELLFFEVLRDIHDSIQKEILYEINRVDESITCEQLTDIFMKFYRMV
                     DSTSILNLMINGEFEILVRKLPDSIIEEYFRHDDFEIGEIISCIPNAKNKDIESFSGA
                     FRAVFLTMLYKREVGSNCFEDALRLMINGLVIQLME"
     gene            26275..27120
                     /locus_tag="PC494_001817"
     CDS             26275..27120
                     /locus_tag="PC494_001817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF3912319.1"
                     /translation="MIKVDDLSFSYTDRDFLQNINFEVGKGEILGFLGPSGAGKSTLQ
                     KILIGMITNYGGSVIVNGVESKRHSNKFYENIGVDFEFPSLYEKLTAIENLKYFGSLY
                     SKKLLSIDELLKSVGLENESNKRVSEYSKGMKSRLNFIKALLHNPDILFLDEPTSGLD
                     PSNSKVMKDIILSEKSKGKTIILTTHNMLDATELCDRVAFIVNGKISALDTPHNLIMS
                     KGAIKVRYTYFDNGEKTSECFLNNTANDKNLNMLIEKNKLLSIHSSEPTLNDIFIEIT
                     GRNLQ"
     gene            27117..27800
                     /locus_tag="PC494_001818"
     CDS             27117..27800
                     /locus_tag="PC494_001818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF3912320.1"
                     /translation="MRLKNLILGDIKFQFKYGFYFLYLFLSIIYICIINVFPTFMREK
                     IAIIMIYSDPAAMGLFFMGAIVLLEKSQRVLNSLAVSPVKVSEYILSKVISLGVISSI
                     VAMFIAITLNLDNIIISTIGTFFSSIIFSLLGLIIASKASSLNQFIVLSIPIEIICFI
                     PPILNVLLDTKSYANLYPFNICISLISGDKNFIMINILILISIIIIIYFITYYFICSS
                     WKKVGGVKL"
     gene            27797..28513
                     /locus_tag="PC494_001819"
     CDS             27797..28513
                     /locus_tag="PC494_001819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF3912321.1"
                     /translation="MIKIINAFKQEFEQIKRDAMLFIVCVSPILCGVFIKFGIPLIQN
                     ISLNKFYYQLNLEPYFLMFDLLLAFITPFMFFFASTMVILGEIDDSISRYLIVTPLGK
                     TGYLISRFGIPGILAFIITMILLIFFSLTKISLLLNLSISLLVLLQGVIISILVISLS
                     SNKLEGMVITKFSGVFMMGILAPFFILNKAQYILFFLPTFWISKAFKEDNYVYMFISI
                     VISLIWILLLFKKFSKKIVK"
     gene            28610..28873
                     /locus_tag="PC494_001820"
     CDS             28610..28873
                     /locus_tag="PC494_001820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF3912322.1"
                     /translation="MKNKIKILREKLGLTQEQLGRLVGTSRQAINAIETGKNEPSIWL
                     AYDISRIFNEPIESVFLFEESERKSRAQISRGEYYGYKKDKNI"
     gene            28845..29300
                     /gene="def"
                     /locus_tag="PC494_001821"
     CDS             28845..29300
                     /gene="def"
                     /locus_tag="PC494_001821"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HDF3912323.1"
                     /translation="MAIRKIRTFDDEILRKKSKYVENVDNKIREILNDMAETMYNTPN
                     GGGLAACQVGVLKRLVVIDLGEGLIKLVNPEIIEQEGEQIVVEGCLSFPEVWGKLKRP
                     KKVTVQALNEYGEKIEIKGSGFMAKCLCHEIDHLNGIVFTDKIIEHVKL"
     gene            29352..29813
                     /locus_tag="PC494_001822"
     CDS             29352..29813
                     /locus_tag="PC494_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine dimer DNA glycosylase/endonuclease V"
                     /protein_id="HDF3912324.1"
                     /translation="MRLWHKDLIDVLPKNQLVSQWRELLAIKGSIDKKGTPNHLLVNK
                     VLNYSIDEFKFYTKIVHDEMLKRNYKPNELKYTSILKWKNRNFANDISNEHSLNLENL
                     YDDWHNKMYLKQCLYNLEEKATCGGIPINEWNILLCKYSKDYELWSGNIMF"
     gene            29863..30765
                     /locus_tag="PC494_001823"
     CDS             29863..30765
                     /locus_tag="PC494_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HDF3912325.1"
                     /translation="MYNKIKYIPINCEIACNKLKRSMPYKWDLNIYRGCEHGCKYCYA
                     IYSHKYINSNNYFEEIYVKTNIVEKLERQLKSSKWKKEVINIGGVTDSYQPIEADYKI
                     MPEILNLLIKYKTPAIISTKSDLILRDYDLIDKLSRITYINVASTITTVNEDTQRLIE
                     PNGVDSMRRFKMLKEFRKTNASVGLHIMPIIPYITDDFDNINSLFRHAKECNVHYVLP
                     GTLYLRGITRGVFFDFVKKEFPELFDKLSILYSAGSLNREYKNQLYKMVNELRYKYSL
                     SSSYSKIMKEKLKNSGDVQISFFD"
     gene            31135..31947
                     /locus_tag="PC494_001824"
     CDS             31135..31947
                     /locus_tag="PC494_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HDF3912326.1"
                     /translation="MYLERPELYKQSEINFWDDEYISKQLLKAHLDTNFEGASRNFNF
                     IEDSVNWIVTVANPANYPKLLDLGCGPGLYAEKFAQKGYKVTGIDFSKRSINYAQNRN
                     KETNLNINYLFQSYLNMNYNEEFDLATLIYCDYGALSTENRRLLMEKIYDSLKPGGKL
                     ILDVFTINKYNNFEEIKYWEINEDGGFWSNEKYMCLQDNCKYNDYNTLEQTLVITEKD
                     ENVFYVWNHYFSKESFLLEVENIGFKSVEFFSNVKGEAYSDDSMTMGLVLQK"
     gene            32995..33756
                     /locus_tag="PC494_001825"
     CDS             32995..33756
                     /locus_tag="PC494_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896901.1"
                     /note="N-terminal region resembles flavodoxins. C-terminal
                     ferrodoxin region binds two 4Fe-4S clusters; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EFR1 family ferrodoxin"
                     /protein_id="HDF3912327.1"
                     /translation="MIGIYFSGTGNSRYCVEKFLQEYDITANSYSIEDNELLQHINNH
                     ENIIFSYPVQYSNVPKILKDFIINHSTLWNGKRVFIIATMALFSGDGSGVLSRILKKY
                     GAITVGGLHVKMPDSIGDEKVLKHSLEYNRKLVIKAEKKVTKAAKKLKHGSPPKEGLG
                     FLSHIVGLFGQRLYFINKTNMYTDKLKINTEECIVCGKCVNLCPMKNLVIKNCMIVAN
                     GQCTMCYRCVNNCAKKAITLLGKKVVEQSNIKKYM"
     gene            33821..34603
                     /locus_tag="PC494_001826"
     CDS             33821..34603
                     /locus_tag="PC494_001826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhzF family phenazine biosynthesis protein"
                     /protein_id="HDF3912328.1"
                     /translation="MEYYIVDSFATKLFKGNPAGVCVLDRRIPLELMQKIAEENNLPE
                     TAFVVKGKGNYELRWFTPKAEIDLCGHATLAAAYVISNFIDVNVKRIDFFTQSGKLEV
                     TRNGNLYEMIFPEIMPIEIELSPQQANLIGCVPSAVYSSRDLILLLNSEQEVINYKPN
                     YAQLRKLTDWLGIIITAQGSNTDFVSRYFCPELDSEDPVTGSSHCNLIPYWSEKLGKH
                     KMVAAQLSNRGGIIQCEVLKDNTVKISGEAVLFMQGTIKIDI"
     gene            34870..35289
                     /locus_tag="PC494_001827"
     CDS             34870..35289
                     /locus_tag="PC494_001827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjdF family protein"
                     /protein_id="HDF3912329.1"
                     /translation="MDKISGKLTVLFEEPFWVGIFERQDGKKYEACRVVFGAEPKEVE
                     VYEFILERFFSLDFGSIKLEKNVTKDNIGYKRMQRKVKKEQEKETIGTKAQNALKLQY
                     EERKQDRKNLAKNRKEEEKERLFNLKQEKRKAKHKGH"
     gene            complement(35392..35658)
                     /locus_tag="PC494_001828"
     CDS             complement(35392..35658)
                     /locus_tag="PC494_001828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HDF3912330.1"
                     /translation="MKNFILIYFIVINSIAFFSMYIDKKRAIRNEWRIKEATLMSIAV
                     IGGSIGSIIGMYSFRHKTKHIKFTFGIPFILFLQFLLVYFYILK"
     gene            35885..36586
                     /locus_tag="PC494_001829"
     CDS             35885..36586
                     /locus_tag="PC494_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3912331.1"
                     /translation="MKFIVEKEVFDKLENVCFGVVVAKGIDNTKEIERISNLLDISID
                     RVEDYFKDKKVKESEEIIPYREAFRSLGMNPNKFMSSIEAMTTRVAKNKKLPHINPIV
                     DLGNSISLKYLLPMGAHDMDFRNDDVYVRFSKKGDKFVPFGETDVELMEEGELIYSVG
                     DMVKTRRWIWRQGEEGKITNSSKNIFFPIDGFTDANLDKVMSAREELAKLLKEIFNCE
                     IKVGFVDKDNPEMEI"
     gene            36668..37276
                     /locus_tag="PC494_001830"
     CDS             36668..37276
                     /locus_tag="PC494_001830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HDF3912332.1"
                     /translation="MKKTIIKNVNPMIENKFIGLFEIEYKNKLDEDKVWMVASRKSSE
                     QLKNIYLKNEEDSVDAVVIVGLHKSSKKLILIRQFRVPINGYIYELPAGLVDEGESID
                     ISVERELREETGLTLLEIKKNKSIDKVYLSPGMSDESVAFVYCICDGDITDEFLEPDE
                     EIEALLISQEDAKEILQSNHKIDTKAFLILQMFVSLGAKLFE"
     gene            37600..38064
                     /locus_tag="PC494_001831"
     CDS             37600..38064
                     /locus_tag="PC494_001831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4624 domain-containing lipoprotein"
                     /protein_id="HDF3912333.1"
                     /translation="MKKLVIILISIISMVSLTACKKSNESKYNNLNNKESGQTTIEMD
                     LDKNYDTSDPFVNARLFCVSNDIDVLDTEISFKMDGDSGIVEIKDNKTDETLWSNTWH
                     GSVDNDTFTISLSNIQKEKEYAICFTGIKINHAVVKVTFESNLVKEKEKPSK"
BASE COUNT        15367 a         3848 c         6394 g        12699 t
ORIGIN      
        1 tttataagtt taactataaa ttaggtttat attttataaa aatttgctaa aaaaaacaat
       61 taaaaattgt aaagaaaaaa gatataatta gaactgtagt aataaatgtt ttattataga
      121 taatagagtt ttaagtatct taaataatat ttggaggaat atgaatggaa ttaagaccaa
      181 gaagtgcaaa attagaagaa tttgataaag taatagaatt aataaactat gtatttagaa
      241 tatcaagaaa tcataaacca actatgatgg aagaatttcc tcttttacta agtaaaaata
      301 atatagaaaa tatgattata atatcagaag atgataaagt ggtttctgat gtaaactatc
      361 taattcagga tgtatctatt caaggaaaca gattgaaggt tgcagctata ggtggagtat
      421 gtactcatcc agattatgaa aagagaggct attcatctaa gatattggat aaagtagaag
      481 aaaaaatgtt ttatgatggt gtagatattg taattatatc aggaacaaga agtctataca
      541 gtagaagaaa ttgtagtttg gtaaagagtt tttataaata tacaataaaa cctgaagatg
      601 taaaaatagc atatgaaata gttgaatttg atgaaactaa ttttgaaaaa gataatgatt
      661 tagataaaat gattgaacta tataatcaaa atagtactag atttataaga acgagagatg
      721 agtttcaaaa actattgcat gcagcaacta ttgcctgggg accaattggt tacaagaagg
      781 tatttataaa ggaaaataat aatataatag gatatttgat aataagaaca ataaaaaaag
      841 aagattctac tgtaggagaa gttgctgaaa tagggttaaa ctctgtaaat gttgaaaata
      901 tattgaaata tgttgcaaat aaatttggat tagaatcttt aaattataaa gtacatgtga
      961 aaaatcttaa agaccagttg aaatgtaatg ggacaaaatc tttggattat caacaaggaa
     1021 ctatgaaaat aataaatttt actaagttgt gtgatagttt aagaagttat tttagtcaat
     1081 atgtagattt tgaattacta aaatacatgg aatttaaaca agttgaaaat aaatatatta
     1141 ttaaatacaa agaagaagaa cttgtaatag aaaatttgga taagcttaat aaactgtttt
     1201 ttgaaaaaaa tgaggaacag tacaatgaat ttaaacatct aaaaaatata tatgaatttg
     1261 ctacaaaggc atttcctgta gattttccat ggactgcaaa tttaaattat caatagtttt
     1321 agatgatatt aaataaaatt gattgatacc tagagttagt ccttgttaaa taagagaaat
     1381 tattggatat tgaaaaagca attttgtaag taattagaaa ggatgagtat tatatggaca
     1441 tacttgatga tatagcagaa tgtatattaa atatgggtgt agataatata gagaatttag
     1501 taaaaattgc tatagataaa aatattgatg tggaagatat ttatgaatat ggtttaaaca
     1561 aaggtatgat aggagcttta gataagtttg agaataagga atactatctt tcagaagtta
     1621 tagtatgcac agatgcatta aataaaggta ttaatctttt gaagggaact ggaaaagtaa
     1681 agaaaaaatc aaagggagta attctgatgt ctgtagtaga aggagatact catgagatag
     1741 gaaaaaatat tgtaaaagta atggtagaag ccactggata taaggttatt gacttaggtg
     1801 taaatagaaa aagtgaagat ataatagaag aagctataaa aaacaatgta gatataatag
     1861 gcttatcttc aatgatgaca actacaatgg aaaatatgaa atcggttata gacgaactta
     1921 atatgattga gatagataaa agaccaaaag taataattgg tggaggacct gtaagtatgg
     1981 agtttgcaga agaaatagga gcagatggat acagttcaaa tgctccaaaa gcagttaaat
     2041 taataaataa acttatagga ggtgaagttt aaatgttttc agatatgact ttacttcagt
     2101 atataaatag tgaagataga ggtttttttc tgcctgatat gggtacaaat ggattgttct
     2161 taataaataa aaaggcatat gaagtatatg atagtgtaga tttgcaatta gaattagcaa
     2221 agactatgga caagtatttt gaatcagatt ttatatactc attctgtgat gggattacat
     2281 tttgtgaaac tctgggttta gatacattaa gaccagatta tgattttcca agtgtattga
     2341 cacatactat aactgacaga gataaattaa gaaaattaga tgttccagac ccttatacga
     2401 gtggacgtat gccactcaat atagagagct tatcagttat atcaaaaagt attaaaaaac
     2461 cactatatga atcgatacaa ggtccattta cacttgcagg tcaattagct ggagctactc
     2521 aacttttaag atgtataata actgataaaa aatttgtaga agaattattg gaatttacaa
     2581 ctgaattggt aagaagatat gctgtagctg caaataaagc aggagcaaaa tatatttcaa
     2641 tagcagagcc aacatcagta accctaagta aagatagatt tgatgaattt atagtaaaaa
     2701 atttaaataa aatctacaat gaacttgatt gttggaaagg tatgcatata tgtggagaca
     2761 ccagagaatt attagataat atgctaagtt gtaatataga tgcagtaagt ttagaccaaa
     2821 ttttagacta tgaagaaatt gctccaatga ttcctagaga tatagttttg attggtaatt
     2881 tagacccaat aaaacttctt ggacgttcta agccagataa gattagaaga gagacactaa
     2941 aattgttaaa gaagatgaga agatatgata actttttatg tgattttggc tgtaactgct
     3001 taaataccac tccagtagaa aatttacaag cagctataaa ggcaggaaga attagttata
     3061 aagaattaga taggattgat attgatgaat tataatagta ataaaaataa atatctttta
     3121 aaggatataa atttagatga tatttttata gataagaata ttgtgctaaa gtttttgggg
     3181 tatggaaata gaaaagctcc agatacaatt agtaaaatcg ttgaaagaga aataagaaat
     3241 ataaatgata ttttagatat caagatatat ataagtgaag ttgatattaa taaaacacct
     3301 aaagaatgta aaaaagcatt tgctgtacta tatacaatag gggataaaat tgattttaag
     3361 atgaatgact atatggaaaa ttgcaatatg atggcagggc tggcattgga taaggtaggt
     3421 atagtatgtt tagattgtat taatgagaaa ataaaaatgt atttaaaagg aaagtatgat
     3481 agtctcaaaa tatcgcatga aatatatcca ggagataaag attttgaagt agagagacaa
     3541 aaggatattt ataactatgt aaaaaataaa tataatagta tagaaataga aattaatgat
     3601 tatcatcaac tatcccccat aaaaagtgtt gcaatgctta ttttaatggg ggatgaagaa
     3661 aatttagaat caagatgtag taagtgtcct agaaaatgct tttagttaat tttcaagact
     3721 aagatttgtt ttgtgtataa attgcaataa tttttttggt cattttatgt ataaactaaa
     3781 aaaattattg caaagtaata ttctatttaa tttgaacaga cttacaaact atagtagttt
     3841 ctttaattca ataagtgtat ttatttcata agttggtata tgattagtat aatttatact
     3901 gttattggaa tttaaccaac aagtatctat tcctgaattt attccaccta agatatcaga
     3961 ggttaagcta tccccaatta ttaaggcaga agatttatca tgacaattaa actttttgag
     4021 agcgtattta aatatttcag gatttggttt tgatattttc aactcttcag atacaaccat
     4081 tccatcaata tattctttta tttttgaatt ttcaagtctt ttcttttgaa ctgcagaaat
     4141 tccatttgtt attataacaa tagtatactt ttttttaaga tattgtaata tatcgattgc
     4201 acctggaatt aaaaatgtac attcacctaa aaaatttaag tacattttgc taagagtttc
     4261 agaatcaaca tccaaagata ttttatttgc aaaaagttca aatctaagta atttaagttc
     4321 attcaaagtt ataatatttt tttcaaggtc gagccaaagc ttatcactta tatttctata
     4381 tgactctata taattctcaa aattaaattc taaatcaaac tcagatagaa gttttttaaa
     4441 agcatgtgat tcacttttct taaaatcaaa taaagtatca tctgcatcaa aaaatataaa
     4501 tttatatgtc ttcatggttt ttactccttt acaagatgac tgcaaaaatt actttacttt
     4561 cactatttga gtcattttgc catttatgtt ttgttcctaa aggaactttt acactatctc
     4621 ctttggacaa agtaaattca tcatcatcca taaaaagttt aacttctccc tccaaaacat
     4681 atgcaatttc atctccatta tgagtaatcc tatcaacaca agaagaagtg tttggagcta
     4741 aatccataat tgcaaattct aaattaccac tagagtctgg aattaaaatc tcatatataa
     4801 cttctttgct tccaggtaaa ataacttttt ttctattatc atgtcttact atcaagtttt
     4861 ttttatctac ctcagataca aaaaatgtaa ataaaggaac gtttagagaa gaggctatag
     4921 attttaatga atttacagat ggattagcaa gacctcgttc tatttggctc aataatgatg
     4981 gtgtaacatc agctagtttt gctaaatctc gaatacttaa gttttgtttt tttcgaactt
     5041 cagctatttt ttcccctaaa tttaaatcat tcatataaat atcctctctt tttaatttaa
     5101 aaaatattaa cttaaaataa tcaagtaaaa tgattatgta gtatgaaatt attataacat
     5161 atagaattag gttttgaaaa aactatgttc aatataatta aataaattaa aatataattg
     5221 acaaagtgga tacagaatac ttaaaatata tttaaataaa attaagcaaa agatagttaa
     5281 tttatgatag gaggggatat tatgcaaata acgacttttg gagctatatt tggtttatta
     5341 atagcaatta ttttaattat aaaaaaattt caagctgtat atagtttaat gctaggagca
     5401 tttattggag gattagttgg aggagcaaat ataacacaaa ctgtagattt tatggcaaat
     5461 ggagctatga atatatcacc atcaattctt agagctttgg catcaggtgt attagctgga
     5521 agtttaataa aaacaggggc agtagataaa atatcagaac agattgtaaa aatatttggt
     5581 gaaaagaggg ctttattttc gattgccatt tcaactatgg tacttgctgg agtaggcgta
     5641 aatttggatg tatctataat aactgtagca cctataggat tatatatagg tagaaaatta
     5701 aattattcta aattgtcaat actattagct atgttgggag ggggtaaagc aggtaatata
     5761 atatcaccaa atccaaatac tatagcagta gcagataatt tttctgtcaa tctctctagt
     5821 gttatgatgg caaatataat tccagcaatt attggagttg ttattacagt tattttagca
     5881 agtatattaa taaataaagg aaataaagta caatcatatg aaattttaga gcaaagagaa
     5941 gatttaccaa gtttatttaa atcattatgt ggtccaatta tagctatatt tctattgttt
     6001 ttaggaaatg tatctcctat agttatagac ccaatgatag cccttccaat aggaggaatc
     6061 gtaactctaa ttgtcacagg aaacttgaac aattcaagag aatatttagc ttttggatta
     6121 tctaagatgc aaggggtatg catattatta cttggaacag ggactatcgc aggaattata
     6181 cagatgtctg aattacaaca gagtacaata ggtgctttac aatttttaaa tatgccacaa
     6241 tttttattgg caccagtttc gggtatactt atgtcattag caacagcatc atcaacagct
     6301 ggtgctacta tagcatcatc tacttttcat gatgctataa taaatggtgg gctatcaccg
     6361 atttcaggtg cctcaatagt aaatgctggg tctagtgtat tcgagcaatt accacatggc
     6421 tcactatttc atactagtgc aggtagtata aacatggata taggtgaaag atttaagtta
     6481 attccatatg aagcattgat aggaatagta atgactataa tttcaacatc tattcaatta
     6541 gttttataat aaatataaat atttaatgaa aaaagtagga ttttgttatt aaatattgaa
     6601 tttattatag taaaaaagaa gattggagtt ttaaagtgaa taaaaaaaag attgttatta
     6661 tagggattat ttattcattt ttagtagtat tttcacttac aaatatgtat gtaaatatgg
     6721 agtataatct aaatgtattt gaatatatta agaagtcact tccatttaca gaagaagaaa
     6781 aaaagtggtt agaaaaacac aagaatttga tttacagctc tgaccaaagt tcacctcctt
     6841 tgagatataa aggtaaggaa gatggacagt ataagggaat tattgttgat ttaataaatt
     6901 ctctgtcaat tcaaattggt agagattttt attttaaacc aaataattgg tggaaagaat
     6961 ctttcgtaaa ttcaatagat gatagtataa agttttttga cttgattcca tcaaaagaaa
     7021 gggcaaataa atttatattt actgacccaa tatacacttt gagtgcaaat atattgaaag
     7081 ataaaaagtc ccaagatata aatagttaca tggatttaaa ggggaaaaca gtagcaattc
     7141 cagaaggtga ttattctata aattttttaa agcaaaaaat tcaagatata aacattttgt
     7201 tgactccaga tataaagact ggagtcaacc atttaatgtc tggaaaagta gacgcagttg
     7261 ttggtgatga accagtattg cgatactata taaataatta tggactttca aataaataca
     7321 gtgttttaag taatcctata tatactaaaa aagcagttct tgctgtacct aaacaatatg
     7381 aagagctggt tagtatttta aataaaggca tttttaaact tcagaaaaat ggagtgtata
     7441 aagatttaaa gaaaaaatgg tattctacgt ataatgaagt tgatgatata ttgtatgagc
     7501 gaggaattgt gcctagtatt tatcttttta taggtataat tttaatatca atttatgttt
     7561 tttatagcta tacatatttg ttaaagatag aaatcaaaag gaaaacagaa caggtaatag
     7621 aaaataaaaa aactttagag gcaactttta atagtattac agatataata atgcttgtag
     7681 atgaaaataa caatatagta gaatcgaaca aagtactata tgactttatg ggtgaaatga
     7741 gttataagat agcagatttg attagcatga taaaaggtgt tattgaaaat accttctctg
     7801 aaaatactaa taaaactagt gaaatagaaa tacacaataa aattttaaag ataaacactt
     7861 ttcctgtaga gtataaaaaa aataatactg agtatatagt agttcttatt aaagatataa
     7921 ctaatgataa aatagtagag gcgaaattac ttagagaaaa caaaatgata tctataggac
     7981 aattagcttc tggggtagca catgagataa gaaatccttt gggtataata agaaataatt
     8041 gctatctctt aaaagataac gttacaatgg aagaagtaaa tgattgtgtt aaatcaatag
     8101 aaagtaatgt agatagggca agtaatataa taaccaactt gttaaatttc gcaagaatat
     8161 cagatgataa tttagaacat ataaatataa gaaattttat tgaaaatata gtgaaacttc
     8221 aatataaaat gttacagtta aagaatgttg aaataaaaat tgactgtgaa cataatttag
     8281 tatgctatat aaatggagaa tcgttaaaac atgtatttat aaatttaatt tctaattcaa
     8341 tagatgcaat acatcaagat ggaaaaatta ttatatactg ttatgaaaaa aattattgtt
     8401 tatttataga ttttaaagat aatggtgaag gaataaaaga agatgcccta aaggacatat
     8461 ttaatccctt ctatacaaca aaaccaattg gtgagggaac tggtttaggt ttatacatta
     8521 cttataatga gattaaaaag aataatggag atataagtgt tgaaagtaaa ttgggggttg
     8581 gaacttgttt tcatataaaa attccattaa ataaagaggt gactatataa tgaaaatact
     8641 attagttgat gatgagctag aatatggagt ggtaatgaaa aaaattctac aaaagaaggg
     8701 ctatcttgta gatatagcac taagtggtga agaagctata aatataatta aaaaagataa
     8761 aaattatgat ttggttttgt ctgatgttat gatgaaaaat atggatggag tacagctatt
     8821 agatagaatt aaatctatta atagagatat agaggttata ttagttacag gatatggaag
     8881 tattgaaaat gcagttgatg ctatgaaaag aggagcttta tcttatttta taaaaagtaa
     8941 tcccattgaa aatttattag aagaagttga aaaggtaaag gcaagtaaaa tatctgtttc
     9001 tgtacaaaaa aataatctgg aatttacttt ggaatctaaa aatagagatt ttaataatat
     9061 cataaaaata gcaaaaaaag ctgcttgtaa agatgttaat atattaatct tgggggaatc
     9121 tggtgtagga aaagatatat tagctagata tatacatagc ataagtccaa gaaagaatga
     9181 gatatttgta cctgtaaatt gttgttcttt ttcagaaaat ctattggagt ctgagttgtt
     9241 tggtcatgaa aaaggttctt ttacaggagc agtagatagt agaaaaggta gatttgaact
     9301 ttcgaataaa ggaactctat ttttggatga aataggagat atacctctaa atgttcaggt
     9361 aaaacttttg aggacacttg aggacaaatc tatagagagg ataggaagta ataaatctat
     9421 taaagttgac tttaggttaa tttgtgctat gaataaagaa ccaaaagtgg aaatatcaaa
     9481 tggaaatata agagaagatt ttttttatag aataagtaca ataacaataa ctataccacc
     9541 gctaagaaag agaagagaag acttaactac tcttatagaa tttttcttaa ataagtacca
     9601 aattgaacat gataaaaaga tacactcgat tgataaggaa gtaaaggatt ttttattaaa
     9661 ttacaattat ccaggaaata taagagaatt aaaaaatata ataaatagac ttgtagtttt
     9721 aagtgaagaa ggcaatttat caaaagacaa tttaaattta atatcaaata atgtatacat
     9781 agatgataaa ataagtatta gacctttaag agaaataaga aaagagtttg aatgtgagta
     9841 tattgaaaaa gttttatctt tgtgtggaaa taatatttca aatacagcta aaaaattgga
     9901 gattagtaga agacagttaa ccaataaaat atcagagtat aatattaagt gagaaaaaaa
     9961 cttctcatta agtgagaaaa aaatttctca aactgtatta aaagataaac agaaaaaatc
    10021 tgtttatctt tttttattat aattttaaaa attaatattt acaataatta ttgctaaatt
    10081 caatattggt gtaaattaaa aatgaaaatt tctatgacat taatacatag aatatatatt
    10141 ttaaataatt ggcatagaaa atgctttata tattaataaa cgtaataaat acttttaatt
    10201 gcgattaaat atattaaggg ggattttcat atgaagctag agctagggaa tatatttata
    10261 aaaaatgttg aatttggaga aaagacagaa gtaaaagatg gagtactata tattagtagc
    10321 gaagaaatag aaaagatagt attagaagat gaaaggattg taagtgtaaa tgttgaactt
    10381 gcaagacctg gcgaatcaat aagaatagct ccagttaaag atgtaataga gcctagagtt
    10441 aaaattggag atgaaagcaa aatatttcct ggaattataa ataaagtgaa gactgtagga
    10501 agtggaagaa cccatgtact tttaggagct tgtgttgtaa cttgtggaaa tatagttgga
    10561 tttcaagaag gcgtaattga tatgagtggt cctactgcta aatatacacc tttttcaaaa
    10621 acaaataata tatgtattgt tataaaagca aaggatggta tagatactca tgattatgaa
    10681 gaagcagcta gaattgcagg attaaaaata ggtgcatatg taggtgaggc aggaagagaa
    10741 gttgagccag atgaagtcat tgtatatgag acaaagccat tattaaaaca agtaaaagaa
    10801 tatccagacc tgccaacagt agcatatgtt cacatgttac aatcacaagg acttttacat
    10861 gacacttatt actatggggt ggatgctaaa cagatagtgc ctacatttat gtatccaact
    10921 gaaataatgg atggagctat aatatctgga aactgtgtag caccatgtga taaggttaca
    10981 acattccatc atttaaataa tccagttata catgacttat ataaaagaca tggaaaagat
    11041 ttaaacttta taggagttat tttgactaat gagaacgtat tcttagtcga taaagagaga
    11101 agctctgata tggtagctaa attaatagaa tttttaggag ttgatggagt tctagtgaca
    11161 gaagaaggtt atgggaatcc agatactgac ctaatgatga attgtagaaa atgtagtgaa
    11221 gttggagcaa atgtagtttt gataacggat gaatttcctg gaaaagatgg caagagtcaa
    11281 tctatagcag acgctactaa ggaagcagat gcagttgttt cttgtggtca aggaaatcta
    11341 gtggttcatt tcccagcaat ggaaaaaatt ataggaactt tagattatgt tgaaatgatg
    11401 ataggtgggt ataaaggatg cttaaatgaa gacggaagca tggatgcaga gctacaaatt
    11461 ataatagcat caactatagc aaatggctat aatcatttga cagcaagata ttattaaata
    11521 agtatttgaa tataaagttc tgttgatata atcattggtc taattgatgt aacaactata
    11581 aagtgatttg gaggattaag agatgagtaa aatcagagtg gttcattata taaacaattt
    11641 ctttgctggt ataggtggag aggaaaaagc agatattccg ccagaaaaaa gggctggtgt
    11701 agtaggacct ggaatagcat ttcagagtca atttaatgat gatgcagaga taatctcaac
    11761 tgtaatttgc ggagatacgt attttggtga aaatattgag agtgcaactc aagaactttt
    11821 aaaaatgata aaagaagaaa gccctgattt atttattgca ggcccagcat ttaatgcagg
    11881 tagatatgga gtagcttgtg ggactatttg taaggcagtt gaagaagagt taaatattcc
    11941 tgtaattaca ggcatgtata aagaaaatcc aggtgtagat atgtttaaat tagatttgca
    12001 tatagtgtct acaggaaatt cagcagcaag tcttagaaag gtagttccaa taatgacaaa
    12061 actaggtctt aaattggtta gaggtgagga aataggacct cctgaagagg aaggatatat
    12121 aatgagagga ataagaaaaa atttcttcca tgaacttaga gggtctgaaa gagcaattga
    12181 tatgttggtt aaaaagatga aaggggaaag ctttgaaact gagtatccaa tgcctgaatt
    12241 tgatagagtt acacctatga aacctgttaa agatttatct aagataaaac ttgccctagt
    12301 aacttctgga gggatagttc caattgataa tccagacaaa attgaatctt caagtgctac
    12361 taaatatgga atttacgatt taacagatat ggattctatg tcaaataaag aatttacaac
    12421 tatacatggg gggtatgaca gagcatatgt ccttgaaaat ccaaatttag ttgtaccact
    12481 agatgtagtt agagagcttg aaaaagaagg tgtaattgga gaattagtag attattttat
    12541 aactactaca ggaacaggaa cgagtgttgg caattctaag agatttggag aagagttttc
    12601 taaaaaattg ttagaagatg atgtagatgc tgtaatttta acttctacat gaggtacttg
    12661 tactcgttgt ggagcaacga tggtaaaaga gattgagaga gctggtatag cagttgttca
    12721 tatatgtaca gtagtaccaa tatcacttac aataggagct aatagaattg ttccagcagt
    12781 agggatacca tatccacttg gaaatcctat gttaggagaa gaggaaagta aaaaaattag
    12841 aaagaatata gttttaaaag ctttaaatgc actaacagaa gatatagaag aacaaacagt
    12901 atttgaataa taaaaataca acacaacact gaaataaaaa aagatatcaa aaaataattt
    12961 tttaaaatta ttttacgata tctttttttt attaggtaaa ttcgaaattt gcatttttta
    13021 aaattaaatt tataaaagtg ataaattagt ttattataat attgatacac aaattcaaat
    13081 tagatatact atgaaaagcg agattattac attttggaac aaatattcaa catattagat
    13141 catattaatt gaacagaaaa aattaacttt atataataat tagaataatg ataagaaaga
    13201 aggtgtatat attgatttca attgccattt gtgatgatga atcctatatg ctaaatcatt
    13261 taaaggaaaa tatagaatta tacatgaagc agaagaattt attatataat atagagcttt
    13321 ttaataaagt agaagattta ctatgcaatc atgaaaagtt taatattgta tttttagata
    13381 tacagatgga agagattaac ggaatgcagg cagctagaaa attaaggtca tatggtaatg
    13441 agtgctttat aattttcgtt acagttttaa atgaatttgt atttgatgct tttgaagtag
    13501 atgctataaa ttatctgata aaacctctat ctaatgagaa actatataaa actttggata
    13561 aaatagttac aaaacttgat gataatgaaa gtaattatat cacaatacaa aaaggttatt
    13621 catattggaa attaaaactt gctgatattt tatattgtga agttataaaa agaaagattt
    13681 atgttcattt aaagaaagag actgtagatt attatgagac tattgaaaat ttagagagaa
    13741 gtttaccaac aaattttttt aggtgtcatc gtagttatat aatcaattta caatatgtat
    13801 atggatatga aaatggtaat gcagttatgg aaagtggaga tagaatacct gtttctagac
    13861 tacgtcaaca aatattttca aaagttatgc ttgagttcat gaaaaatagg aggatataag
    13921 atgattaatt tattttcttc cgatttattt ttaaagtaca gttttttatt ttcttttatt
    13981 gtatatagaa ttttaatggt aatagtgcaa tactattttc taatcagttt tacaaatgtt
    14041 aattcaaaat tttggtgttt tattttatat tcgataattt caattttttt aatcattata
    14101 aatacatatt ttaatttata taatttattt tcttcacaga ttctattttt tcttatgact
    14161 tttttatttg taaagtacat aataaaacaa tctactgttt tatctatagt atcaactttg
    14221 ttagtatatt taattgaaca attagtatat ggatttacag ctccattaaa ttacttgata
    14281 tttactagtg atataaatac agatatttat aaatttgata taaatatggg actatcttct
    14341 ttaattacta ttataatagc tggatttata tattggtata gttctaaaaa gtttaatatt
    14401 aaggtcatga actttgataa atatatagca attttgatga ttccattgtt gcttataata
    14461 ttatttatgc aatcatttga atatagttca aatataaata tagatacaag tcttgggatt
    14521 gtaaagctgc tattaaatac ttctataact gaagaaattc aagcttttct tttttctata
    14581 attggaacta tatgtgtatt tttttctcta tttaccttta agaaactaat tcaagctctc
    14641 gaagatgaca aggagagggc aattatgaat caacagattc atgctcaaaa aaactatatt
    14701 gaagaagcga aatcacgatt atcacaaact atatccttta gacatgattt taataatcat
    14761 ttagctattg tcaatggatt gttgaaaaaa gaccaaattt taaaagcaca agattattta
    14821 aataagcttg aaaaagtaac aagtgaccta tcattttctt gtaatacaca gaatattgtt
    14881 attgatgctc ttttcaacaa taaattaagt atagcaaaac aattaggcat agaggtagat
    14941 tgtgaagtaa ttatacccca aagcactaac atgaacgatt ttgacctatg tatagtgttt
    15001 gctaatgcta ttgacaatgc aattaaagct tgtagagttg tagataaaca aaataggtat
    15061 ttaaagcttt ccactaagtt agagggtgga ttttttatga tagaaataaa aaatagctat
    15121 aatccaataa ataattatac aagtggctca ggtataggtc ttttaaatat aaaagaaatt
    15181 gctaaaaaat atcaaggggc tataagtata gataagacat cagattattt tcaaataaat
    15241 gtattgctgg ttatttcatt acattgcgct agtatttgat aacaatttca ttgaaaatag
    15301 tatttgtaag ctatattatg tacttgaata gagaaagttt gatatataga aatgaggagg
    15361 ttactaaaat gaaagttgga aatataaatg gtcaagcacc aattacaaat ggtttagata
    15421 gttgtcaaag tgaggtacaa ggcttagaac aaaagaaaaa atcattacag gatgaaatag
    15481 agaaagtaag aagtgataaa agtattgatg gtgaaacagc caaattaaaa atagaagctt
    15541 taaaaaaaga aatggaagag attgaaaata aaattcaaga gttaaaagga aataaagcaa
    15601 aaaaaacaaa taaagaagaa aataatgttt cagaagtaaa taataatcta ttagagagaa
    15661 aaaaagaacc ttctaataat gaaaatgtaa aacaattata tgatgttttt gaaagaagca
    15721 atgtagacga acaatgggat aatacttatc gtgttctcca agatgataaa aacttaaaag
    15781 taaaatttaa tagacctata tagtttattt ataaaaatag ttaatatttt aattatcacc
    15841 actttttaga agaatacaca ctttatttta aagacccaca tatttattta cagttagcac
    15901 atttatatgt ggttttataa ctattattta caagtctata ttgataactt ttacatagta
    15961 tataatgttt aaatacttat tcaaatttat ctatacataa acaaaaaaag agattttaaa
    16021 atctcttttt agattgttga cttatggctt tttgatttaa taaaatcaag aagccgtttg
    16081 aattttatct gttggctgat acccttctga tattgaaaca ccatttttgt ttccaaaatc
    16141 gtttaaaatt aagaacttat tatgaatgac tatttcatta tgaacaataa gcagataaca
    16201 tgaatcttca atcaatgttt taacagtagc attaaatgct tgcttataca gttctatcgt
    16261 ttgtttgaac tgtccattaa agtaaatatg agtcaataac ataactatat ctacacaaat
    16321 taatataaat tttttatact gtacattatc taactgttga ttatctgtat tacaacatga
    16381 ttgaatttaa aaagccatca acacatagaa tgttgatggc ctgaaaatag atttaaaatc
    16441 tcttttttat tatatattaa ttatttttta aatttatatt ttttgcatca gattttctaa
    16501 tagctaagtc aaaccctcta aatctaatca ctatagggtc attaagagga gctatctttt
    16561 tcacttcaac ttcagtgcca tctattagtc ctaaggctag aagtctcttc ataagttttt
    16621 catttccagc tatattgtct ataattccct tttgtccaag ttttaagttg taaacagtca
    16681 ttattaacac ctcctaatga aaatcattat caaactttat atttataata tataacaaaa
    16741 agagcaaatt gtcaatatat aacaaaaaat aaacatacta agttagtatg tttataaaaa
    16801 atagtataca tgggatacta atagcatcta gcaaaaaacc acttactaat ggtacaacta
    16861 aaaaggcttt tggagaatca ccatattttt gtgtcaaaga actcatattt gccagagcgt
    16921 ttggagtagc tcctattcca tgtccaatca aaccacttat tatgatggca gaatcaaaat
    16981 cttttccaag tactctaaag caaataaata ttgaaaatag gattataaag attacttgaa
    17041 aagttactat taagagaata ggaggtaata atgtagataa ttcaaataaa tctatattca
    17101 taagtgataa agttaaaaaa attcccaatg aaagttcttt taaaaaatct ataagtttaa
    17161 aatttaattc tagtatattt atcttatcat ttaaatttct aaaaataaca gccgaaaaca
    17221 tacaagttac aacagagggt aatagtatat taaacgttat atagaagcat ctacttataa
    17281 tttctcctgt atttatacaa ataaatatga gaagaacctg ttccaaaaat acagatggtg
    17341 ttattgtttc ggagaagtta ttatttttta tcctattctt atttctaaaa aatttacttc
    17401 caaatctctt tagatttcta ttatatctag gaatcgacaa gtctatattt gatgatggtt
    17461 ttaatttata tttatttatt agaaatttag ctacaggaca tcccaatata ccacccataa
    17521 taagtcctat tgttgcagca gataatccaa ccccaactgc tccttctata ccgagatttt
    17581 ctattgtaag tccaaatgca gcagaataac catgaccacc ttccatagat acatttccac
    17641 acataagccc taaaagaggt tcaagtttta taatctttga tattgtaata gctaatatat
    17701 tttgacaaaa tgccaatact ccacacaaaa tccaatatct aaataataca ctaccacctt
    17761 tctttataag atttatgctt atttcaagtc ctatagttgt aaaaaagaag gttatgaaat
    17821 ttggcattaa atttccactt atagatatat ctgctatatt aaaatattta aaaaataaat
    17881 ttagaaaaca aaataataga cctcctatta ctggtgcagg tatacagaaa ttatttaaaa
    17941 agttaacttt attcttcaat aaattaccaa ttaaaaagaa gaatatagat agtgtcaagg
    18001 tttgcactat atcaaaactt aaggtaatca aaataagtcc tcctttgtaa ttcaaagttt
    18061 taattatata acttaaattc ttatgtattg aaattttatt atcaaatgta tattaataaa
    18121 tgtatattaa aaagaatcag tagatataat tagatagtca taaattaaat taaaatattt
    18181 taatgagata tgactttttt agaattaaaa accgtagtat attgatataa tagaaataag
    18241 acttaaaaat ctgttgatag tattatttat aagtacagta ggaggataaa atgtttgaaa
    18301 atttacctaa gatagattta cattgccact tagatggaag tgttagagta gaaaccatgc
    18361 ttgatatagc tattaaagag aaaatagatt taccttcaaa taatatggat gaaataaaaa
    18421 aattagcaaa ggtttctttt aattgtactt cactagatga atatttagaa aaatttgatt
    18481 tacccttaaa agtaatgcaa tctaaggaaa atttaaaaag aattactttt gaacttttgg
    18541 aagatgcaag tagagaaaat gtaaaatata ttgaaattag atttgcacca ttacttcaca
    18601 cccaaaaagg tatgagtgtt aaaaatataa ttgagggtat aattgaagga attagagaag
    18661 ctgaaagtat ttatgatata aaaggcaatt taatattagg ttgtatgaga acaatgacct
    18721 caaaagaggc attattagta attgaagaag ggaaatcatt tgtaaataaa ggtgttgtag
    18781 cagtagactt gtgtggtcca gagaaagagg gattttgtaa ggaatataaa gatgttttta
    18841 aattagcaag agaatatgga tataaagtta caatacatgc aggagaagct gcaagtggag
    18901 aaaatgtatt ggatgctata aatattttaa aggcggatag gattggtcat ggggtaaaaa
    18961 ttaaagacca taaaaaggcg tataatttag ttaaagataa aaaaatattg cttgaattat
    19021 gtccaactag taatgtacaa actaagacag tagattctta tgaagcacat ccattttata
    19081 ctttttataa agataattta catgtaagta taaatactga taatagaact gtatcagata
    19141 taaatttaag ttcagaacta aatgttatat ttgatacttt taaactagga ttagaagact
    19201 ataaaataat ttatagaaat gcagtagaag ctagttttgc agataaagaa actaaagagt
    19261 atttgaatag tttaatttaa tagataaaaa tatttaaact ttaaattaag ctattaaatt
    19321 gataaaaata cattgtatta ggagaaaaaa tgtgaaagat tatgaagatg ttgtttatat
    19381 taaactagtc aaaaaagaac ttgaagaatg gaagaaaaat atattaaaga aaccttctat
    19441 atttgacaaa gcatcaaagg gtatacagaa taaatttaat ggagtattgc cagataaata
    19501 tcatgaaata attacttctt ctataaaagt aatgacaaaa accgtactgt ttggatataa
    19561 atatgctaca aagccaccac ttagaaatat gtcattagaa gaaagagaaa aattagtttt
    19621 agaaaaagct aaaacttaca agactacagc aatgattgaa ggggcaggaa caggggcagg
    19681 aggaatcctc ttaggtttat ctgattttcc tttgctttta ggtattaaag tgaaattttt
    19741 atatgatgta gcttcaatat atggatatga tgttaaagat tatagagaaa ggatttatat
    19801 attaaatata ttacagttgg ctttttctag tcaacagcat ataaacaaaa cttttaaatt
    19861 gatgaataac tgggatgaat atgtaaatag tctaccagaa gacatcaatg attttgattg
    19921 gagaacattt caacaagagt atagggatta tttagattta gctaagtttt tacaactaat
    19981 gcctggaata ggagcatttg taggatttta tgtgaatgga aaattaattg ataaattatg
    20041 tgaaactgct gtgtctgctt atagattgag gattcgagag cttaagttat aagaaaaatt
    20101 ataacataaa aaattagtta tacaatatat ctatatgtat ctaattttgc attgataaaa
    20161 acaattatgg ataaaaggta aagcatgata gaatctaatg tagaggtttg tattttaatg
    20221 gaaaaattta gtttttattg cttaagatac aaattgaatt acgaagagat tgaattatga
    20281 agagaagtaa ttgggaggaa tattttcatg acaaatttgc caaaacaatt tgatagcttc
    20341 aatgaagcta gacaaaaagg atttataaat gcaaaggaac ttaaggaaag tgggaaaaag
    20401 atggttggag ttttctgtac atttactcca gttgaaattc caatggcagc tggagcaact
    20461 gtagtaggtg tatgcggcgt tagtgaagag ccaatacctg atgcagaaag ggtgcttcca
    20521 agaaatcttt gtcctttaat taaatcaagc tatggacatg caataacaga tacctgtcct
    20581 tatttctatt tttctgattt gttgatagga gaaaccactt gtgatggtaa gaaaaaaatg
    20641 tatgaagaac ttgcaaaagt taagccaaca tatgtaatgc atttgccaaa tacttcaaaa
    20701 ggagaatttg cctataaact ttggaaagat gaaatgataa gattaaaaga agaggttgag
    20761 aaatctttag gtgtaactat aactgaagaa gatataagaa ctgctataaa agataaaaat
    20821 gaagaaagag aacttttaaa agagttttat gcacttggta aattacaacc atctgcactt
    20881 acaggccttg agttacataa tgttttatat caagcaggtt ttaaatttga ccgtgcagaa
    20941 cttaaacatt ctttaagaaa agttatagat gatatgaaag aaagatatga aaaaggtgaa
    21001 tgtcctgttc aaaaagataa gccaagaata ttgataacag gttctcctat tggtggaata
    21061 agcgaaaaaa tagttaaaac tttagaagat gcaggggcat cagtcgttgc atatgaactt
    21121 tgtggagcta ttagatcaaa cgatttattg gttgatgaag aaatagaaga tgtatatgat
    21181 gctttaacac aaaaatatat aaatataggt tgttcttgta tgatgaataa tgacaatcgt
    21241 attgaattat tagatagaat aatagatgaa tataatgtag atgctgtaat agatgtagtt
    21301 ttacaagcat gtcatacatt taatatagaa agttatagaa taagagaatt tgttacaaaa
    21361 gaaaaaaata agccatttat gtctcttgaa actgattatt caaaatcaga tactgaacaa
    21421 ttaagaacta gatttgaagc gtttgtagag atgttgtagg aataaataaa agtaggagga
    21481 actatgttta gtataggagt tgactcaggg tcagtggcaa caaagggtgt gctatttgat
    21541 ggtgaaaaaa ttattaagaa aataattata ccaactggat ggagccctaa aagtacatct
    21601 aaacaggtct atgagttgct aagtagtgaa attgacaaaa aagatataaa aaaggtggta
    21661 ggtacaggtt atggaagggg agtaatggat tttgctgata agaaagtaac agaaataact
    21721 tgtcatacta gaggtattta ctttttaaac aagaacataa ggactatttt agatgtaggt
    21781 ggtcaagata gtaaagttat aaatttagat agagatggaa atgtatttaa ctttataatg
    21841 aatgataagt gtgctgcagg aactggtcga tttttagaga ttacttctaa ccttttagga
    21901 agcgatattg aaagtataga tacattagct aaaggatatg aaccagttaa tatatctagt
    21961 atgtgtacag tttttgctga gtctgaaatt gtaagtcttc tagctcaaaa catttctact
    22021 ggagaggtag cagcagggat acttaaatct attgcaaata aatccacctc aatgttagca
    22081 agaggtgagg taatagatga agttgcattt actggagggc ttgcaaaaag taaagaacta
    22141 gtaaaaatga tagaagaaat actgggtaaa aaaattttta ttgcagaaga tactcaaata
    22201 ataggagctt taggagctgc tgtaatagga tttagataaa aacatataaa aagaaaatga
    22261 gaagctgaat ttattataaa taaattcagt tttttatttt attttattta tttataaagg
    22321 aaaactttgg tataattgat ttaaatgatt gtatatttgt aaatacttga tatttagtca
    22381 tatataacat tataatttta aaaattagct caaaataagg gggagaaagc gtgaaaaaat
    22441 ttacttcaaa aaaagtaaca aggtttgttg cgctgttttt aatatctatt ttagtaatgt
    22501 caacaattcc tgtatcagct gacaatagca atacattgaa tcagataaaa aaagcagaat
    22561 acagtgagac gtataaacaa tatctaaatg atgctaaaaa tggatgtaca gaaaaatata
    22621 atgggattat accaaatcca tatcagttgg aaggtactca aatccaaagt aaaggaagaa
    22681 cagctccaac atcttatgac cctagaaaat taggtcttat gacatcaata aaaaatcaag
    22741 aggatttagg aatctgttgg gattttgctg caatggcaac cttagaaagt ttcttaaagt
    22801 taaataatta tggagactat gatttatcag aagaacactt aagatggtgg gcttcagatg
    22861 gtgaatatgg atggtctgta aatgatatga atggtgcttt aaattatgaa gctatgggat
    22921 atttaacatc ttggtcaggt cctaaattag aaaaagatat cccatacaat ggtagagtat
    22981 ctaaagcaca aggagcaaaa aaaccaacta atatgaatac agcacctact gtttttaatg
    23041 tgacagatgc tgtgtgtgta agcaatgaca taaattctac aaaaaatgct atattacagt
    23101 atggagctgt aacatctggt tattatgaag atattaaata tcaaagtgat gaccaaaatt
    23161 catattattg tccaacaaaa agttttaata caaatcatgc tatttcaatt gtaggttggg
    23221 atgataacta ttctaaagat aattttaatg caaatattag accatcaaaa aatggtgctt
    23281 ggttaataaa aaatagctgg ggagattata attctgaggg tggatatttc tggatatctt
    23341 atgaagacaa gacacttatg tctgatatag ataatttttc aatcaaaggt ggtaaaaaac
    23401 caaatgatga tgagaagatg tatcaacatg actatgcaag tattgtacct ttaatttcaa
    23461 aaaagataac agctgcaaat gtatttgatt tcaatagagg cgatgaaact ctaaaatctg
    23521 taatgttctt aactgaaagt ataggagcta agtatgaagt atattatgct ccagtagtaa
    23581 atggtatacc tcaagaaaac aatatgaaaa aattaaaaga aggtactgcc caatattcag
    23641 gatacataac agttccaatt gattcttttg atataccaga aggaaagggt gcaattgtag
    23701 tcagtataga ggggaaaaat ggagagtcaa ctataggttc tgagtcaaat gtaccaggat
    23761 atgatacatt taaagcaaaa gctaatttag gtgaaagtta tatcatagat aatactggaa
    23821 aattctttga tataaataga gatagtaact tctatccgtg taattttact ataaaagctg
    23881 ttacagaaaa gtcttctggt gagagtatcc caaatgagtc tttaattggt agtgatagat
    23941 atgaaactgc tatcaaagtt agtcaaaatg gtttcaattc ttcagaaaat gtagttttag
    24001 taaatggcag ttcaatagta gatgcattgg cagcaactcc ttttacatct gctataaatt
    24061 caccaatatt attgacacaa aaagaagctt taaattcaaa aactaaagct gagatacaga
    24121 gattaggtgc taagaaagta tacctaatag gtggagaaaa ttctataagt aaagaaattg
    24181 aacaacaatt aaaaagctta aatatatcga tagagagaat atcaggaagt gatagataca
    24241 agacaagttt attattagct caaaagttaa atggtataaa aaatgtatct caaatagcag
    24301 ttgtaaatgg agtgaaagga ttagctgatg caattagtgt aggcgctgca gcagcagaaa
    24361 ataacatacc aatcatactt gcaaatgaaa agagcgaatt gcaaggagct gatgaatttc
    24421 taaattcatt aaatatagag aaatcttata ttattggagg aacagcatcc ctatcaaaca
    24481 atctagaaag taagttaaaa aatccaacta gattatctgg tagtagtaga gacgaaacta
    24541 attcaaagat aatagataat ttttataaaa aagatacttt aaaaaatgca tttgtagtta
    24601 aaaatggaat caagaatcaa aatgatttaa tagatggatt ggcagttggt cctttaggag
    24661 caaaaactgg gtcaccagta attttagttg gtgataaatt agctgatagc caaaaagaag
    24721 ttcttaaaaa taagacttta gaaaaagtaa ctcaagttgg tggaggagca aataaaaatg
    24781 catttaaaga gttagtaaaa ttaaaaagtg ctaaatagag tacttaagta ttaacatata
    24841 ttagtgtgta ttagtaactt atcttaataa aagctgaaaa taattacttc aaattattga
    24901 taaataagat aatcaatgat tgtaaagttt tgttttcagc tttaaattta tgtagtataa
    24961 gtttaaaaac ataaaaaagg gttactttat atagaaatat agaaaatctt acattttata
    25021 tataaataac ccatatttaa ttaacttttt atagtgttct aatagatatt attgaactta
    25081 atggtaaata taatgtgtaa gtttcattta aagttggatt agattcatct atatatcttg
    25141 agcaaagtgt aattgataag ctatctgctt ctataatttc accatataga ggacaactgc
    25201 taaagtaaga atgtacttca acatatttat ttaagttttc ttgaacataa tcgtaaaaac
    25261 ggttttttgt agtagtagcc ataaaatcaa ctcctttatt ttttattaaa gttgaaactt
    25321 ttaaaaagat aaatatgatt acttctatta gaaactaagt taaaaaataa gcaaatagat
    25381 atgaaaatta gaataatata ttatttatat cttaattata acactagata ataaaaaatg
    25441 ctatataaaa ttcagaattt tcgaaagttt ttaagcttat ttttaaatat actaataata
    25501 ctattgacat tagatagaaa aagtattata ttgactatat aaattatttt agtcaaactg
    25561 gagggaaaag atgcctaaat catattctga taaagaaaga gagtatataa taaaaagact
    25621 taaagaagaa gcaagattgt gtatggagca atatggtatt agaaaaacta ctgttgatga
    25681 gcttgtaaaa cgggtaaaaa taccaaaagg aactttttat ctattttttc aatcaaaaga
    25741 attactcttt tttgaggtat taagagatat acatgactct atacaaaaag aaatcttata
    25801 tgagataaat agagtagatg aaagtattac atgtgaacaa ttgacagata tatttatgaa
    25861 attctatagg atggttgata gtacttcaat tttaaatctc atgataaatg gagaatttga
    25921 gatattggtg agaaagttac cagattctat aattgaagaa tactttagac atgatgactt
    25981 tgaaattgga gagattatat cttgcatacc aaatgcaaaa aataaagaca tagaaagctt
    26041 tagtggagca tttagagcag tttttcttac catgctatat aagcgcgagg ttggaagtaa
    26101 ttgttttgaa gatgctttaa gattaatgat aaacggatta gttatacaac ttatggaata
    26161 gaatttaaat tttgtttgct aataactttt attaaaaatt attaacaaac aaaaaaatta
    26221 tattttattg accatatagt caaaatagtc aaaaatttga aagggtgata ttgaatgatt
    26281 aaagttgatg atttatcatt tagttataca gatagagatt ttttacaaaa tattaacttt
    26341 gaagtaggaa aaggggaaat actaggattt ttaggaccat caggtgcagg aaaatctaca
    26401 ttacaaaaga ttctaattgg aatgataact aattatggag gaagtgtcat tgtaaatgga
    26461 gtagagagta aaagacactc aaataaattt tatgaaaata taggagttga ttttgaattt
    26521 cctagtttat atgaaaagtt gactgcaata gaaaatttaa aatattttgg gtctctatat
    26581 tctaaaaaac tactatctat tgatgagtta ttaaaatcag taggactaga aaatgaatca
    26641 aataaaaggg tatctgagta ttcaaaaggt atgaaatctc gattaaattt tataaaagct
    26701 ttattacata atccagatat tttattttta gatgaaccaa caagtggtct tgacccatca
    26761 aatagcaagg ttatgaaaga tataatttta tcagaaaaat cgaaaggtaa gactattatt
    26821 ttaacaactc ataacatgtt agatgcaaca gagctttgtg acagagtagc gttcattgta
    26881 aatggtaaaa tatctgcttt agatacacca cataatctta ttatgtcaaa aggagctatt
    26941 aaagttagat atacttactt tgataatgga gaaaaaactt ctgaatgttt tctgaacaat
    27001 actgctaatg ataaaaattt gaatatgctt attgagaaaa ataaactttt atcaatacat
    27061 agtagtgaac caacattaaa tgatattttt attgagataa cagggaggaa tttacaatga
    27121 ggctaaaaaa tcttatttta ggagatataa agtttcaatt taagtatggt ttttattttt
    27181 tatatctttt tttaagtatt atatatattt gtattatcaa tgtatttcca acttttatga
    27241 gagaaaaaat agctataatt atgatttatt ctgacccagc agcaatggga ttgtttttta
    27301 tgggagctat tgtacttctt gagaaaagtc aaagggtttt aaattcctta gctgtatctc
    27361 cagtaaaagt atctgagtat attttatcaa aggtaatttc attaggagta atatctagta
    27421 ttgtagctat gtttattgct attacattaa atttagataa tattataata tcaactatag
    27481 gtaccttttt ttcttctatt atattttctt tgcttggatt gataattgca agtaaagcat
    27541 ctagtttgaa tcagtttatt gttttaagta ttcctattga gattatatgc tttattccac
    27601 caatactgaa tgtacttctt gacacaaaat catatgcaaa tttgtaccct tttaatatat
    27661 gtatttctct tattagtgga gataaaaatt ttataatgat taatatttta attttaatat
    27721 caattataat aataatttat tttataactt attattttat ttgtagcagt tggaaaaagg
    27781 taggtggagt aaaactatga taaagattat aaatgcgttt aaacaagagt ttgaacaaat
    27841 taagagagat gctatgcttt ttatagtatg tgtttctcca atattatgtg gagtatttat
    27901 aaaatttgga ataccattaa tacagaatat atcacttaac aagttttatt atcaattaaa
    27961 tttagagccg tatttcttga tgtttgattt acttttagct tttattacac cttttatgtt
    28021 cttttttgct tctacaatgg tcatattggg agaaattgat gacagcattt caagatattt
    28081 aatagtaact ccgcttggta aaactggtta tcttatttca cgatttggaa taccaggtat
    28141 cttagcattt attattacta tgattctact tatctttttt tctctaacta aaatttctct
    28201 cttgttaaac ttatcaattt ctttattagt tttattacaa ggagttatta tatcaatatt
    28261 agtgatttct ttatcatcaa ataaactaga aggaatggta attacgaaat tctcaggtgt
    28321 ttttatgatg ggtattttag caccattttt tattttaaat aaagcacaat atattctgtt
    28381 cttcttacca actttttgga tatcgaaggc atttaaggaa gataattatg tctatatgtt
    28441 tatttcaatt gttatatcat taatatggat tttattatta tttaaaaagt ttagtaaaaa
    28501 aatagttaaa taagaaaatt taatatataa atgtaaggtt gacttgacag taatgttgaa
    28561 aaatgttaca tttaagatgt aaagttaacc ttacatgaat ggagcaaata tgaaaaataa
    28621 aataaagata ttaagagaaa aattaggatt gacacaagaa caactaggga gattagttgg
    28681 aacatctaga caggctataa atgctataga aactggtaaa aatgaacctt caatatggtt
    28741 ggcatatgat atttcaagaa tttttaatga accaattgaa agtgtatttt tatttgaaga
    28801 aagtgaaaga aaatcaagag cacagataag taggggagaa tattatggct ataagaaaga
    28861 taagaacatt tgatgatgaa attttaagaa aaaagagtaa gtatgtagaa aacgtagata
    28921 ataagataag agaaatatta aatgacatgg cagagaccat gtacaatact ccaaatggag
    28981 gaggattagc tgcatgccaa gtaggagtat taaagcgatt agttgttata gatttaggag
    29041 aaggacttat taagcttgtt aatcctgaaa ttattgaaca agaaggggaa caaattgttg
    29101 ttgaaggatg tttaagtttt cctgaagtat ggggtaaatt aaaaagacca aaaaaagtta
    29161 cagtgcaagc tctaaacgaa tacggtgaga aaatagaaat taaaggttca ggttttatgg
    29221 caaaatgtct ttgtcatgag atagaccatt taaatggtat agtttttaca gataaaatta
    29281 ttgaacatgt aaaattgtaa gatagattgg ttattgaatt tataaaatat tttatagtaa
    29341 ggagttaaat tatgagatta tggcataagg atttaattga tgtattacct aaaaatcaat
    29401 tagtaagtca atggagagag ctacttgcta taaaaggttc tatagataaa aaaggtactc
    29461 caaaccatct attagtgaat aaagtattga attatagtat agatgaattt aaattttata
    29521 caaaaattgt acatgatgaa atgttaaaaa gaaattataa acctaatgaa cttaaatata
    29581 caagtatatt aaaatggaaa aatagaaatt ttgcaaatga tatatctaat gaacatagtt
    29641 taaatttaga aaatttatat gatgattggc ataataaaat gtatttaaag caatgcttat
    29701 ataatttaga agaaaaagca acatgtggag gaataccaat aaatgaatgg aatatattac
    29761 tttgtaaata tagtaaagat tatgaattgt ggtctggaaa tatcatgttt taattactat
    29821 agattaacat tatagtatta ttgtatataa agaggtgatt atttgtataa taaaataaaa
    29881 tatattccaa taaattgtga aatagcttgt aataaattaa aaaggagtat gccatataaa
    29941 tgggatttaa atatttatcg tggatgtgag catggatgta aatattgtta tgctatttac
    30001 tctcataagt acatcaactc caataattat tttgaagaga tttatgtaaa aacaaatata
    30061 gtagaaaaac ttgagagaca acttaaaagc agtaaatgga agaaagaagt aatcaatata
    30121 ggaggagtta cagatagtta tcaaccaata gaagctgact ataaaattat gccagaaata
    30181 ttaaacctgc taataaaata caagacacca gctattattt ctacaaagtc agatttaatt
    30241 ttaagagatt acgatttaat tgataagcta tctaggatta catatatcaa tgtagcatct
    30301 acaattacca cagtaaatga agatacacaa aggcttattg agccaaatgg tgtggattca
    30361 atgagacgat ttaaaatgtt aaaagaattt agaaaaacta acgcatcagt tggtctacat
    30421 attatgccaa ttataccata tattacagat gattttgata atataaattc gctatttaga
    30481 catgcaaaag aatgtaatgt acattatgtt ttacctggga ctttatactt aaggggtata
    30541 actagaggtg ttttttttga ctttgttaaa aaagagtttc ctgaattatt tgataaatta
    30601 tcaatactat atagtgcagg ttcacttaat agggagtata aaaatcaatt gtataaaatg
    30661 gttaatgaac ttagatataa gtattctcta tcaagcagtt actctaaaat aatgaaggaa
    30721 aagttaaaaa actcaggaga tgtacagata tctttttttg attagtttta tataaaaaaa
    30781 ttttttttac tatgatgatt aaaatttatt aaaattaaaa tttattgaca aatataaaat
    30841 ttaaatatat aattaattca taaaataaaa atatgaaagg atgatgttgt tcggtgatat
    30901 ttgatatcat aaaatcgttg atataagtat tgctggaaaa gagtgaataa aatcaaattt
    30961 aataagcaaa caaagtaaag ctatagtttt attgttgtgc ttaaaaatat ttggttctat
    31021 tttactctta tttaaactca tctttttgaa gttaaaccac agagtaaact ctgtggtttt
    31081 tttattttaa aaataaattt taaggagtgg tatgttttgt taaacaaatt atgtatgtat
    31141 ttagaaagac cagagcttta taaacaaagt gaaattaatt tttgggatga tgagtatatt
    31201 tcaaagcaat tattaaaagc acacttagac actaattttg aaggagcaag tagaaatttt
    31261 aactttatcg aggattctgt aaattggata gttacagttg caaatccagc taattatcct
    31321 aaattacttg atttaggttg tggtccaggt ttatatgcag agaaatttgc acaaaaaggt
    31381 tataaggtaa ctggaattga tttctcaaaa cgttctatta actatgcaca aaatagaaat
    31441 aaggagacta atttaaacat aaattacttg ttccaaagtt atttaaatat gaactataat
    31501 gaggaatttg atttggctac tttaatttat tgtgattatg gagctttgtc aactgaaaat
    31561 agaaggttat taatggaaaa aatttatgat agtttaaaac ctggaggaaa attaatatta
    31621 gatgtattta caataaataa atacaataat tttgaggaaa ttaaatattg ggaaataaat
    31681 gaagatggag gattttggag taatgaaaaa tatatgtgtc tacaagataa ttgtaaatac
    31741 aatgattata atacattaga acaaactctt gtaataaccg aaaaagatga aaatgtattt
    31801 tatgtttgga atcactattt ttcaaaagaa agtttcttat tagaagttga aaatattgga
    31861 tttaagtctg ttgagttttt tagtaatgtt aagggtgaag catattctga cgatagtatg
    31921 actatgggat tagttttaca aaaataataa tttttttaaa atgaataaat aaaaacttga
    31981 aacctttaac aataaaataa cataataaaa gcttacatat tgaaaaatgg aaacttttat
    32041 gttattttta gtacattaca aatttgctta tataaaaatc aatacttgaa ttattatttt
    32101 tatgtgaaat ttatctatag tatattttta taaacaagta atgttattaa aattaagtat
    32161 gtagttaaaa gtgtatagca aaaaggctgt tatattaatg ttagaggttc agggaaaata
    32221 tataaagcaa agtatttaca gataatgtag attgcacagc tataagttag ataatagaat
    32281 tatgtaatca agaatttaca acaaagtata agataaggat aatgctaaat tgccatacag
    32341 gtgctagatg tgtaaatgga tttaattaat actattgata aagtgcaaca agcacataaa
    32401 ccaattgatg agattattaa aactataaga gatatagttg acataattaa aatattggaa
    32461 cttgtttata attttaaatc aaatcaataa tgattaagat taaaataata ttaaggcatc
    32521 aatgttataa gagtacaata taaggagtac tatatagtac tccttactta tacatattag
    32581 gcaataggaa attttttcat agttaaattt tcaagtattt tttaggaaac tttataattg
    32641 agaattaagg gtatagtatg tgatgaactt actgaattta taattaggtt atataatgga
    32701 ataatcatca atagttttac tttagggaaa atatatgctt aaggaagtat agcttactaa
    32761 tattattaaa atgtatattt aaaatgataa aaaaagaatt agacaagtat ttagtaaatt
    32821 gactatgcaa aattctatca agcaggaacc ctatgacttt agtcatggga ggttcagtag
    32881 gtaacttgtt gaattaagtt tatattattt aaataaacta cttaatttag ataatataaa
    32941 aagtcagaat tttaagaata gagctatata atcttagcta ttaggagaat tactatgata
    33001 ggaatatatt ttagtggaac aggaaattca agatactgtg tagaaaaatt tttacaagaa
    33061 tatgatataa cagcaaattc ttattctatt gaagataatg aacttttaca gcacatcaat
    33121 aatcatgaga atattatttt tagttatccg gtgcaatata gtaatgtgcc aaaaatattg
    33181 aaagatttta taataaatca ttcaactttg tggaatggta aacgtgtttt tattattgca
    33241 actatggctc tatttagtgg agatggctct ggtgtgttat ctagaatatt aaaaaaatac
    33301 ggtgctataa ctgttggtgg attacatgtg aagatgccag atagtatagg agatgaaaag
    33361 gtattaaaac attctttaga gtataataga aagcttgtaa taaaagcaga aaagaaagta
    33421 actaaagctg ctaaaaaact gaaacatggg tcaccaccaa aagaagggtt aggttttttg
    33481 agtcatattg tagggttatt tggacaacga ttgtatttta tcaacaaaac aaatatgtat
    33541 acagataaac taaaaattaa tactgaggaa tgtattgtat gtggtaaatg tgttaattta
    33601 tgtccaatga agaatctagt aattaaaaat tgtatgattg ttgcaaatgg gcaatgtaca
    33661 atgtgttatc gttgtgtaaa taattgtgct aaaaaagcaa ttacattgtt aggtaaaaaa
    33721 gttgttgaac agagtaatat taaaaaatat atgtaagaaa tttaaagttt tattgaatgt
    33781 aaattgatgt atattttatg ttagaaagag aggttaaata atggaatact acatagttga
    33841 ttcatttgca actaaactat ttaaaggaaa tcctgctgga gtttgtgttc ttgacagaag
    33901 aataccttta gagttaatgc agaaaatagc agaagaaaac aatttaccag aaacagcatt
    33961 tgtagttaaa ggtaaaggaa attatgaatt acgatggttt actcctaaag cagaaattga
    34021 tttatgtggt catgcaactt tagcagcagc ttatgtaata tcaaatttta ttgatgttaa
    34081 tgtaaaaagg atagatttct ttactcaaag tggaaagctt gaagttacac gaaatggaaa
    34141 tctatatgaa atgatatttc cagaaataat gcctattgaa atagagttat caccacaaca
    34201 agctaatttg ataggctgtg taccaagtgc tgtttattct tcaagagatt taatcttatt
    34261 gctaaacagt gaacaagaag ttataaatta taaacctaat tacgcacaat tgcgtaaatt
    34321 gacagactgg ttaggtataa taatcacagc acaaggaagt aatacagatt ttgtatcaag
    34381 atatttttgt ccagaattag attcagaaga ccctgttact ggttcatcac attgtaatct
    34441 tattccatac tggtctgaaa agttgggaaa acacaaaatg gtagctgctc aactttctaa
    34501 tcgtggtggt ataattcagt gtgaagtgtt gaaggataat actgtgaaaa tttctggtga
    34561 agcagtcttg tttatgcagg gaacaataaa gattgatatt taaataagta taataactaa
    34621 tttattatga aaaataatta attttcttag tgttaacaat aataaagtag agttaaaaaa
    34681 cttgatttca cttaaatcaa tatgatagat gttgatacta agattgacaa gcatgattaa
    34741 aaaagataat atttaatcta taaagataaa aacacagtct ggttggtagt ccagacgcag
    34801 caatagctgt cagtaacctg cctccttggt tgtccgttct ttagaaagta atttaaggag
    34861 gaactagcaa tggacaaaat tagtggaaaa ttaacagtct tatttgaaga accattttgg
    34921 gtaggtatat ttgaaagaca agatggtaaa aaatatgaag catgtagggt agtttttgga
    34981 gcagaaccta aagaagtaga agtgtatgaa tttatacttg aaagattttt ctcattagat
    35041 tttggtagca ttaaattaga aaaaaatgtg accaaagaca acattggata caaaagaatg
    35101 cagagaaaag taaaaaagga acaagaaaaa gaaactatag ggactaaggc tcaaaatgct
    35161 cttaagcttc aatatgaaga aagaaaacag gatagaaaaa acctagctaa aaatagaaaa
    35221 gaagaagaaa aagaaagact atttaatttg aaacaagaaa agagaaaagc taaacataag
    35281 ggtcattaat tttaattaaa tatcttttta ataattgcta gaaaaaggtg tataaaattt
    35341 ttaattttat acaccttaat ttattgaaaa gaataaggtt ttatatttca attactttaa
    35401 aatataaaaa tatactaata aaaattgtaa aaatagtata aatggtatac caaatgtaaa
    35461 tttaatgtgt ttagttttat gtctaaaaga atacattcca attatagaac ctatactacc
    35521 tccaattact gctatagaca taagagtagc ttcttttatt ctccattcgt ttctaattgc
    35581 tcttttctta tctatgtaca ttgaaaagaa agcaatagaa ttaatcacta taaaatatat
    35641 tagaataaaa tttttcacag tcttgcctcc ataaaaatat attatacatt ataaaacaag
    35701 atatttgttt tggaaagtta aatttgtaat tagtacatat aaaatatttg ataagaacaa
    35761 atataatatt aattggaaaa tttaaaaaaa ttaaacaatt agcaaatagg gggtatattt
    35821 ataagacaca aagtgataaa atctatttag aaaataatgt aaaataacag gaggataaag
    35881 caaaatgaaa tttatagtag aaaaagaagt ttttgataaa ttagaaaatg tatgctttgg
    35941 tgtagtagtt gcaaaaggaa tagataatac taaagaaata gaaagaataa gcaacctttt
    36001 agatataagt atagatagag tagaagatta cttcaaagat aaaaaagtaa aggaatcaga
    36061 agaaattata ccatatagag aggcatttag aagtctaggc atgaacccaa ataaatttat
    36121 gagttcgata gaagcaatga caacaagggt tgctaagaat aagaaacttc ctcatataaa
    36181 tcctattgta gatttaggaa actctatttc tttaaaatat ttacttccaa tgggtgctca
    36241 tgatatggat tttagaaatg atgatgtata tgttagattt tctaaaaaag gggataaatt
    36301 tgtaccattt ggagaaactg atgttgaatt aatggaagaa ggagaattaa tttattcagt
    36361 tggagacatg gtaaaaacta gaagatggat atggagacaa ggagaagaag gaaaaattac
    36421 taatagctca aaaaatatat tttttcctat agatggtttt actgatgcta atttagataa
    36481 ggtaatgagt gcaagagaag aattagcaaa attgttaaag gaaatattta attgtgaaat
    36541 taaagtaggt tttgtagata aagataatcc tgaaatggaa atataataag ttgttgaata
    36601 cttgttaaga tattatattt acttaatgat gttaaaaagg tattaaaaaa gaaaggtcgt
    36661 agtaaatttg aaaaaaacta taataaagaa tgtaaatcca atgattgaaa ataagtttat
    36721 aggacttttt gaaatagagt ataaaaacaa attagatgaa gataaggttt ggatggtagc
    36781 atcaagaaaa agtagtgagc aattaaaaaa tatttatttg aagaatgaag aagatagtgt
    36841 agatgcagtt gtaatagttg ggcttcataa aagtagtaaa aaattaattt taataagaca
    36901 atttagagta cctattaatg gatatatata cgagttacca gcaggtcttg ttgatgaagg
    36961 agagtctata gatatttccg ttgaaagaga acttagagaa gaaacaggac ttactctttt
    37021 agaaattaaa aaaaataaaa gtattgataa agtttattta tctcctggaa tgagtgatga
    37081 atctgttgcc tttgtttatt gtatatgtga tggtgatata acagatgaat ttttagaacc
    37141 agatgaagag attgaagcgc ttttaatttc gcaagaagat gcaaaagaga ttttacaaag
    37201 taatcataag atagacacaa aagcattttt gattttacaa atgtttgtga gtttaggagc
    37261 taaattattt gaatagatat atagaaaaga ggttatatag aagagtaaaa taataaagtt
    37321 tattttactt gtgtaaatta taatctcttt ttttatacaa taaagtataa ttttgtgtat
    37381 ttttaaataa gtgatttgac tcttaaattt tcataatatg ttataaacca atttaagata
    37441 ctacaataat taaaattcca aaattattta acatatttgc aattaaaatg agaaaatgta
    37501 aaggctgaat gattgaaaaa tttgatgtaa aatagtagct tagtttaata ctatagtttg
    37561 tagggttaaa aattagaaat tgtaagggag ataaattcta tgaaaaaatt agttattatt
    37621 ttaattagta tcattagtat ggttagcttg acagcttgta aaaaaagcaa tgaaagtaaa
    37681 tataataatt taaacaacaa agaatccgga caaacaacca ttgaaatgga cttagataaa
    37741 aattatgata cttcagaccc atttgttaat gcacgtttgt tttgtgtgtc taatgatata
    37801 gatgttttag acacagagat ttcttttaaa atggatggag atagtggtat tgtggaaata
    37861 aaggacaata aaacagatga aactttatgg agtaatacat ggcatggaag cgttgataat
    37921 gatacattca caatttctct ttctaatata caaaaagaga aagagtatgc tatatgcttt
    37981 actggaatta aaataaatca tgcagttgta aaggttactt ttgaaagcaa tttagttaag
    38041 gagaaagaaa aaccctcaaa ataaattcca gcttttctat aacttgatat tcagtacata
    38101 aaagcagttg atatttatga ttgactgctt tttcttatca aaaaggatag gttgtgcatt
    38161 tttacttgaa atagtttatg cacatcaaaa gttggtgagc atgatattgg aaatggtaag
    38221 catgaaatct tgataataca aggaaataaa tttaagtttt caattaagta tatttccata
    38281 atttagttaa caataagcta attattat
//
LOCUS       DAMKNB010000032        38098 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.034, whole genome shotgun sequence.
ACCESSION   DAMKNB010000032 DAMKNB010000000
VERSION     DAMKNB010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 38098)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38098)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38098
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.034"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            complement(166..2832)
                     /locus_tag="PC494_001832"
     CDS             complement(166..2832)
                     /locus_tag="PC494_001832"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HDF3912334.1"
                     /translation="MENTNLSKTYNPKDFEARLYKKWMDEGYFKSKPNPDKKPFTIMM
                     PPPNITGQLHMGHALDHTLQDILIRWKRMDGYEAFWLPGTDHASIATEVKVVERIKKQ
                     EGKTKYEIGREEFLKRAWEWKDEFGGKISNQLKQLGDSCDWDKERFTMDEGCNEAVIE
                     FFVSLYEKGHIYRGNRIINWCPDCKTTLSDAEVEHEEHDGNFYHIKYPLKDSEDFLEI
                     ATTRPETMIGDTGIAVNPEDDRYKHLIGKTAILPLVGRELPIVADSYVDLEFGTGAVK
                     MTPAHDPNDFEVGLRHNLEQLNTMNEDGTMNEVCGKYEGMDRFECRKAIVADLKEQGY
                     LIKIKEHNHNVGTCYRCHTVVEPRLSEQWFVKMEELAKPAIDILKKGELEFVPDKFDK
                     TYLQWLENIRDWCISRQLWWGHQIPAYYCQECGEIVVARKMPDKCPKCGSTHFKQDED
                     ALDTWFSSALWPFSTLGWPNKTEALDYYYPTSVLVTGYDIIFFWVVRMAFAGMFCMNE
                     KPFDHVLVHGLVRDSQGRKMSKSLGNGIDPLEIIEQYGADALRFTLTTGNSPGNDMRF
                     YMERVEFARNFANKLWNASRFVFMNIDEDIIKNMTRESVKEDLTLADKWIISRANNIV
                     KEATNNMDKFDLGIALQKIYDFTWSEYCDWYIEMVKPRLYGEDANAKSAALYTLTYVL
                     EKILKLLHPYMPFITEEIYTHLPTVEGCIIVSEWPKYNEEDNMAEEEDMMNLLMEGIR
                     SIRNVRAEMNVPPSKKAKLIIIPSEEKIEAIELGKDYFITLASASNVEIAKDKSNVPE
                     DAVGVVIDGVEIFIPLNELVDFEKEIERLSKEKKKLEGEIKRVNGKLANQGFLAKAPE
                     SLIEEEKAKKEKFEEMIKSVEERLTNLESKIK"
     misc_binding    complement(2908..3170)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(3471..4298)
                     /locus_tag="PC494_001833"
     CDS             complement(3471..4298)
                     /locus_tag="PC494_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HDF3912335.1"
                     /translation="MKIKDNKAVFHVFIRIFLIAVLILTGTLLEEKINNVPVENISSK
                     GENTLELLSQSNTLGEIIYKASQEETKGPGATSEKVAYITIDDGPSKYTNALLDILKE
                     NDVKATFFMLNQNMKNHKEEVRRVLEEENSIGFHSVSHDIHKLYKSPEVTVGEFNTCN
                     NTLQEITGQSSKLIRLPYGSKPYMPEGSYNKLMANDYLIWDWNLDTQDWKSSTSQIVS
                     NILYYGRKRDELVVLIHEKEQSLNALNNIIRILKERGYTILPITENITPKNFWQENL"
     gene            complement(4346..5782)
                     /locus_tag="PC494_001834"
     CDS             complement(4346..5782)
                     /locus_tag="PC494_001834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron hydrogenase"
                     /protein_id="HDF3912336.1"
                     /translation="MNTRNDNSKILEIYKMKLFGELVKAVWNDDIEDIENLPNKILNE
                     DLKDNLNNYFSGKFDKDTMVNLIRVTMGLDVTEDTDKNLKESLHEAVNLDEVKRPIIS
                     VISDACKYCDENNKEDESCKIRSKHINCNEEDVCSACGDCVSRCKLGAISDKIEFIPM
                     IKLLKDIKSPVYAIVAPAFVGQFGKDVSPGKLRTALKKIGFEDMIEVALAADMLTAKE
                     AYDYYEHMKKDEEGCFITSCCCPIWVSLIQNSFPQILENVSPSVSPMIACGRAVKILN
                     PDAKVVFIGPCMAKKKEAMLEDIKDAVDFVLTFKELQEIFDALELNPAIMDESNRVEA
                     SLSGRVYARTGGVSKAVKLSVRRIDKNIKFEEKAFEGTKECMDGLKKVLNKEIEATFI
                     EGMGCVGGCVGGPKRILSVEEGTKNVDEYSESTNMETPFDNLNVLQFLTSLGIKRVES
                     LGEKEEEKVKKIFSRDIKSNKKENKYKK"
     gene            complement(5869..6738)
                     /locus_tag="PC494_001835"
     CDS             complement(5869..6738)
                     /locus_tag="PC494_001835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HDF3912337.1"
                     /translation="MKLQKMGMRTIKTGISVTLCMILGDYLVENMFYSLVACIISVQD
                     TVKGSLKTGINRVEGTILGGIIGFIFAIIKAGDPFLCGLGVMCSIYLCNLFKIKSVVV
                     ACVTFLAIHLGVGNSDPVYYSLHRVLDTSVGVLFGVLVNYYVARPNYLNSVIDEFKKI
                     EELSMLLIEDKILRKENLNVEKFEEEVEKLEEIYSKLIDELDYSLSETNIEKIENALR
                     ICREIHFHMQSIELLENKLYLKEHTYKYLKKTYNVDKLDWNIDEEKSPVFNYHLMKIM
                     IEIELLRKLNKSY"
     gene            complement(6896..7549)
                     /gene="phoU"
                     /locus_tag="PC494_001836"
     CDS             complement(6896..7549)
                     /gene="phoU"
                     /locus_tag="PC494_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HDF3912338.1"
                     /translation="MVNNSLDISIDTLKEQTVLMMEKCEEAIEKSVTCMIEKDLEGAR
                     KVVEDDEEINKLREEIRDKSIELIVLKQPMARDLRFIYSLGNISIELERIGDYAANIA
                     REMLKIGGEAYIKELIDIPKMAKECKSMMSQTREALILFDASIAYDVGTKDDIVDGLY
                     EQVQIDCLKIMHENSNTIDQGVKLLLIGRYLERIGDHITNVCEKIIFAIEGKMVEIG"
     gene            complement(7577..8341)
                     /gene="pstB"
                     /locus_tag="PC494_001837"
     CDS             complement(7577..8341)
                     /gene="pstB"
                     /locus_tag="PC494_001837"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HDF3912339.1"
                     /translation="MELIDKIKMSVKDLDLFYGDKQALKKINMDIKENKVTALIGPSG
                     CGKSTFIRTLNRMNDLIEDVTIKGNISVDGEDIYTSDDVINLRTKVGMVFQKPNPFPM
                     SIYDNVAYGPRTHGLRDKKQLDKIVEESLKGAAIWDEVKDRLKSSALGLSGGQQQRIC
                     IARAIAMRPEVILMDEPTSALDPISTLKVEELIEDLKKDYTIVIVTHNMQQAARISDE
                     TAFFLNGEVIEFSDTKTMFTTPVDKRTEDYITGRFG"
     gene            complement(8360..9184)
                     /gene="pstA"
                     /locus_tag="PC494_001838"
     CDS             complement(8360..9184)
                     /gene="pstA"
                     /locus_tag="PC494_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003460575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HDF3912340.1"
                     /translation="MRKFKENLLKSLVYLSALFTIVSLVVIVGFIFIKGIGNMNFNFL
                     FSNYSASGDGGILPMIITTLYTVVVSIVVATPIGILAAIYLQEYAKKGKAVTAIRFAT
                     ESLSGIPSIVYGLFGGIFFVVTLKMGYSIVAGSLTVAIIILPVIIRTTEEALKTVPQA
                     YRESSLALGATKFQTLYKVVLPSAIPGILSGVILSVGRIIGESAAILLTAGTVAKMPG
                     GIFDSARTLTVHSYLLTKESGDIATAASIGIVLIVIVLALNMLARFVAKKLNKANY"
     gene            complement(9186..10103)
                     /gene="pstC"
                     /locus_tag="PC494_001839"
     CDS             complement(9186..10103)
                     /gene="pstC"
                     /locus_tag="PC494_001839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HDF3912341.1"
                     /translation="MIVKSRLVGLEKNDNNGNKTKYVIEKVAKNIFLLSALVAVASLL
                     LIIGFVFYKGLRPFIFEGYSFIDFLTGADWVPSANKFGISSMIVASIFATLGALVIGV
                     PVGILTSVFIAEVAPKRLAKIMSPAVELLAGIPSVLYGVFGLAVIVPTIQSIFNLPKG
                     QSLLAIVIVLAVMMLPTIISVSETAIRAVPKAYKEGSLALGASKIETIFKVVLPAAKS
                     GVLAAVVLGVGRALGETMAVILVAGNSPVMPTAITDSVRPLTTNIALEMGYAFGTHQE
                     MLFATGVVLFTFILILNLVLNKLSNKAVN"
     gene            complement(10484..11719)
                     /locus_tag="PC494_001840"
     CDS             complement(10484..11719)
                     /locus_tag="PC494_001840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF3912342.1"
                     /translation="MRIFYLEIKRVLHSRRTLILLLLALVLSALMAFLPITYEGINYL
                     DDNGKVVELSGLDAIKYKKTIYANNSEISSGVVTPKKLKHALNIWKKTEEKYGKVGSE
                     DFPLDVYSKSILPIRPLLNRLPEAFANSETGFATELSEINTNDLDSFYEQCKTHLNDI
                     MKIERQTSSAQMKAQELYRKVDTPFEIYPGYSKDAFDYIIFYIFILLIICVAIAAPTF
                     SGEYQTQSDSILRCTKHGHIRLAFTKILALFSIFIIMFVICISIHLAISDLAFGTECL
                     KTSFQMLFSVISLVNINLLQAQILIAIGGLISILAMVSLTLFLSAKCKDSLTSMLIAF
                     SICLIPMGIGVSWIGYLLPPGGIGFKISLLYQMTSFNFLHLGGMSFWTPHIILFFSVI
                     EIPIFIFLAIRTYCKHQVS"
     gene            complement(11720..12607)
                     /locus_tag="PC494_001841"
     CDS             complement(11720..12607)
                     /locus_tag="PC494_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF3912343.1"
                     /translation="MELKIEHVTKKFKDKIAVEDVCLTLTPGVWGFLGANGAGKTTLM
                     RIITDIMKPTNGKILYNGKNIYTMGAEYRNLLGFLPQEFGFPQDFSVKDYLEYIAALK
                     DVPPREVKGKINNLLEILTLSDVKNKKIIKLSGGMKRRVGIAQAMLNDPKILIMDEPT
                     AGLDPGERVRFRNFISEFSHNRVVLISTHIVSDIEYISTQNAIMKSGKILDVGTTDKL
                     VKKVEGKVWECLISNRDISKYEMNLRIINQRSEKNNQVSIRYLAEKSQIDNSIAVEPR
                     LEDLYLWLFPEAVYSKEGK"
     gene            complement(12752..13867)
                     /locus_tag="PC494_001842"
     CDS             complement(12752..13867)
                     /locus_tag="PC494_001842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF3912344.1"
                     /translation="MKKINNFTYRKLRDKYKFIKREKNTEAYLKYKLYIMLAIYTGIV
                     LVLMFMADYTFSNFSNPLVKWLKLRRDVLFFLVFIIGYITIFNFYWKKPWNYLREIIN
                     ATHTIYQQNDELVELSKPLKEIEQQMNQIKMSVLLSQQAVKEAENKKNNLVMYLAHDI
                     RTPLTSVIGYLSLLKEIPNMDNSQKSKYTEVALDKAQYLEKLINELFEITRYNSNQIK
                     INFEKVDLYYMLLQLKDEFYPLLSEKGNRAILKANESLTIKADSEKLARVFNNILKNA
                     IAYSYPNTEIIISAVHKDSKVDIAFRNYGQTIPEEQLSAIFEKFNRLDEARKSDMGGA
                     GLGLSIAKEIINLHGGDITVQSKDEVTTFTISLPTST"
     gene            complement(13903..14601)
                     /gene="vanR"
                     /locus_tag="PC494_001843"
     CDS             complement(13903..14601)
                     /gene="vanR"
                     /locus_tag="PC494_001843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002594737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanR-ABDEGLN family response regulator
                     transcription factor"
                     /protein_id="HDF3912345.1"
                     /translation="MSGKILVVDDERDIADLIEVYLTNENYIVYKFYSGLDALNCINL
                     NEFDLAILDVMLPGVNGFSLCQKIREKYTYPIIMLTAKDEETDKITGLTLGADDYVTK
                     PFRPLELVARVKAQIRRYKKYSGNLQSGEELSHIFSFLGLELNTQTYECHLNGKALSL
                     TPTEFSILHVLLKNKGSVVNSENLFHVIWKDEYYNKSNNTITVHIRHLREKLGDTVDE
                     AKYIKTIWGVGYKI"
     gene            complement(14982..15662)
                     /locus_tag="PC494_001844"
     CDS             complement(14982..15662)
                     /locus_tag="PC494_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF3912346.1"
                     /translation="MQTKILIIDGDKDNCQKLKGFLEEKGISIDLAYNCEEAIGKIFS
                     NKYDLIFLEIILSDGDGWTLCKKIRNVTTCPIVYMTYINEDQSILNALNSGGDDYLIK
                     PLNLEILYAKVKAILRRMNSYVNNNENNTKLEEYNRTSGVIKLEDKIIKLTPTENKLL
                     NFFIENPEKTLTTKEIYEHVWMNEYLEDNYSVVVAVNGLRKKIEKDYKNPQKIITIRG
                     AGYYFNKE"
     gene            complement(15712..17727)
                     /locus_tag="PC494_001845"
     CDS             complement(15712..17727)
                     /locus_tag="PC494_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HDF3912347.1"
                     /translation="MKKYNILKGTLIVLIVSLLAITGLNILYKYDNKYTYKSIRASNG
                     ILTIDNDTFTKGKLVFLIDDWEFYNHKIFKPNDFTEQDIKPEYVFIGQYPDFSMRKGN
                     QSPYGNATYRMRIKNEGKDKLLSLELPEIFSASEVWINGEMVSKLGDVGTEKYRPKIK
                     NSVVSFIAKKNTEIIINVSNFSHYYSGLYYPPALGETKDISNMMFYRLLFYSIICFTT
                     FAIAIFSLSVWFLSNKSKIYLYFGCMCVFFAIHVSYPFVHLLGLPLVSFTYAVEDLSY
                     FMVVLCIICINGSISKIEENKVYRFLILPLGITMSIISIVIPIILLPYDMYFVNIYGK
                     LIDIYKYIVFIYILMSSLVSIYKKTCSEHISSYILVSVNTVFGISILFDAVTSNRFEP
                     IFTGWQTEYCGFVIVILFSVMMINRNRIIIKENEKLTRNLEHEVEVRTNELTTLLNER
                     KRFLADVAHDLKAPVSAIQAFIDLIKVGNIHVDEETRTYLYAINQKSNEVQNRVRSLQ
                     EFTSQDKSIGISEKICLNNFIKEIYENNLPDTQACGVNFETYVLEKKIYAKINKEMLT
                     RAFENLIYNALTFTPFDGKIILSMDKEDGFAIIKISDNGKGIPPENIPKVFDRFFTER
                     DNNEPKGQGLGLYIVKSIIREHGGEIFVDSELGKGTVFTIKLSLCFL"
     gene            complement(17799..18476)
                     /locus_tag="PC494_001846"
     CDS             complement(17799..18476)
                     /locus_tag="PC494_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF3912348.1"
                     /translation="MYNLLVVDDDVDILNINQIYFSNIGFNVYTSETAKDAMDIVESI
                     VLDCIILDISLPDIDGYKMCNDIKEKVNIPIIFLSNYEHEEEKVRGFLAGGDDYITKP
                     YSLKELELRIYARMRQYKNITSVPNVLKFSALVINVNSRKVTFDGESIDLTTMEFEIL
                     LFLAENKEQVFSKIEIYNQVWKMPDIGDQHTVQVHIAQMRKKINSLSREHQYIQTVWG
                     KGYKFVP"
     regulatory      complement(19056..19139)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01786"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class II; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01786"
     gene            complement(19372..20214)
                     /locus_tag="PC494_001847"
     CDS             complement(19372..20214)
                     /locus_tag="PC494_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein"
                     /protein_id="HDF3912349.1"
                     /translation="MFKKKIGVLLASTMLVGALAVGCSSNSGGSGDSGDSSKVSVSGS
                     TSIGPLMETIGEKFQEKNQGVSVEVQQIGSSGGIKNAIEGTSEIGMSSRDLKDEEKSA
                     GLKETKIAIDGIALITNTANSVKNLTMDQVKGIYTGKITNWKEVGGNDAPIVIVSREE
                     GSGTRDGFQEIVGFDSEELTKDAQISDGSGNIKTTVEGNENAIGYISFGYVDEKVNSL
                     KINDVEATDANVIANKYPISRPFILVNKEDGLSEKGKALIDYILSDEGQALVSEKGFI
                     KVNQ"
     gene            complement(20466..22250)
                     /gene="pepF"
                     /locus_tag="PC494_001848"
     CDS             complement(20466..22250)
                     /gene="pepF"
                     /locus_tag="PC494_001848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HDF3912350.1"
                     /translation="MGTDRSTIEEKYKWKIDKMYSSKEEIEKDISKVKNLIQEVKEYK
                     GKLSESKENLYKVLNISENASRIVQNLYVYTHMKQHEDTRINDNQGRATKTEMLSTDL
                     GVATSYIVPEILAIEENKLSEYLKDEKLSFYTKYIKDILRDKPHTLSEREEEILAATS
                     ELSTIPENVYDMLAYADMEFPEIEDEEGNKVKLSHSNYSLFIKSKNSRVRKDAFEGEF
                     STYEKYKNTFASTLYGGIKSEIFYAKTRKYNSAIEASLFSDDVSLDVYNNLISAIDKS
                     IPNLNKYVELKKKFLGLNEIHMYDLYVPLTDKFDMDIPYDKAQDIILEALKPLGEEYL
                     KVIKSAFDEGWIDVYDNEGKKGGAYSWGSYDSHPYILMSYKNDLNSLFTLIHELGHSV
                     HSHYSRTSQPFLYSDYKIFVAEVASTLNELLLINYLLENSKSKDETIYLLNYYLEQFR
                     TTVHRQTMFAEFEKIVHQRVESGKPLTADEFTNIYYKLNEKYYGKSAIVDKQIGIEWA
                     RIPHFYSNFYVYKYATGFSAASALSQQILSEGSTAVDRYINFLKSGGSEYPLEQLKSA
                     GVDMTKKESIEEALNVFAELVNKLEKEL"
     gene            complement(22316..22981)
                     /locus_tag="PC494_001849"
     CDS             complement(22316..22981)
                     /locus_tag="PC494_001849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HDF3912351.1"
                     /translation="MIDIGSKEIAIRLLLALIIGGIIGLEREKIRQFAGFRTHILIAI
                     GSCIVSITSIQLFFDYNLYTNADPARMPAQVLSGIGFLGAGAILKNKGGVKGLTTAAG
                     MWATACIGIAVGYGYYELAILGGLFVMIALFVLRIINTFLFSQEKNVLILKLSNLDSI
                     PFLYDKFEKNQLIVRNMEIECRNEEYWKVNFFVSYAKRIHLHDVMKEINMIEGVINVD
                     YLD"
     gene            complement(23132..23293)
                     /locus_tag="PC494_001850"
     CDS             complement(23132..23293)
                     /locus_tag="PC494_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartyl-phosphate phosphatase Spo0E family
                     protein"
                     /protein_id="HDF3912352.1"
                     /translation="MANNELEALKNEIEAVREEINTYIEYPEIFQEELVESSKKIDIL
                     INKYMYLSK"
     gene            complement(23371..23880)
                     /locus_tag="PC494_001851"
     CDS             complement(23371..23880)
                     /locus_tag="PC494_001851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gx transporter family protein"
                     /protein_id="HDF3912353.1"
                     /translation="MKTRKMTFLGLMIGYSLALYVLETYIPNPLIVIFPGAKLGLSNI
                     ITLISLMLLGVKDTVIIVTIRVILSSIFAGPLSYLLFSIGGAYLSLLFMYLASKIKDL
                     SLIGISIIGAIGHNIGQLIVASLIIENILAIGYLPFMLMASLVTGMFVGLVSRYTIPK
                     LKHFYSKFY"
     gene            24086..24304
                     /locus_tag="PC494_001852"
     CDS             24086..24304
                     /locus_tag="PC494_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HDF3912354.1"
                     /translation="MTVYDLKIGEKGFINSIDGDIKLSKRLLALGCINSTEIEVKKVA
                     PLGDPIIIRFRGFDLAIRKSDAKNISLQ"
     gene            24322..26268
                     /gene="feoB"
                     /locus_tag="PC494_001853"
     CDS             24322..26268
                     /gene="feoB"
                     /locus_tag="PC494_001853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein B"
                     /protein_id="HDF3912355.1"
                     /translation="MINVALLGNPNVGKTTVFNLLTGSNQYVGNWPGVTIEKKEGFLG
                     KEIKVVDLPGIYAMDTFSNEEKVSKSYLENEDVDVIVNVVDASNLSRNLYLTTQLMQF
                     NKPIVILLNMLDIAESKGVNIDAKKLSEELGVIVVPIIAKKKNGVDRIEEEIKGATQK
                     AFIYQKNFGSETETYKKLESILSRCTKTTYTQKKSISDKIDNIVLNPILAYPIFIGVL
                     FLLFKFTFDWVGGPLQEGFASLIEAYISAPVSDMLSNSSPWFKSLIVDGIIGGVGGTL
                     PFFPLIFTLFFGISLFEDSGYMSRTAFLMDKVMRKVGLSGKAFIPIVMGMGCSSPAIM
                     ATRTLESEKDRRVTALIAPLMTCGAKLPIYALFVAIFFPHNAALVTTSLYLVGIVMAI
                     VVALFLNKTAFKTEAEPFILELPEYRIPTIDALIKNTWNKSKGFLIRVVTVMFAMSVV
                     IWGLSSFNVFGYTEDINVSFLATLGHIISPIFKPLGFDDWRTSVAILSGLGAKEIVVN
                     SLNILYGNLTVVLPTIFNGVTAYTFLIFTALYTPCIAALATMKKEYGNKMMFTSFAYQ
                     FILAWIMAFIVKSIGGVLFMGNSIIEALIGGIIIVLALFILFNKFKSTKNGNVCSGCS
                     ICSGCPSANSCSSKEDSNKKNNAH"
     gene            complement(26447..27502)
                     /locus_tag="PC494_001854"
     CDS             complement(26447..27502)
                     /locus_tag="PC494_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HDF3912356.1"
                     /translation="MTIQDYMLETPVRMREIISNADSLFNEVKRTNLKKIIITGSGTS
                     YHSGVQVQPYLQNLLDIDVVKMYPFMITEDTFKFDNENTLVVGVSQGGSSYSTYNAMK
                     LAEDKGCKIASMAGCKNALIDEISDYILTVNCGEEKSGAKTKGYYCTKLNLMLLGLQI
                     AREKGIISSEKYNEEINKILDAINRFEAVYKLSKQWIERNKEKLVNSKEIRIIGHSDI
                     YGDTLEAALKLLETMRIPVTGYEFEEFIHGIYNAINSDSTIFILDTGKEPRVTKMIDV
                     LSGWTENVFAIGRDVTENDKNLKIDITDNPYYQTFNFIVPIQLICGEIPTLRGVDPSV
                     PKDTRFHMKLGSKKLNK"
     gene            complement(27550..28350)
                     /locus_tag="PC494_001855"
     CDS             complement(27550..28350)
                     /locus_tag="PC494_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HDF3912357.1"
                     /translation="MNKLTKKELRSMFWRSFVLQGAFNYERMQNLGYCYSMLPAIKKL
                     YNKKENQAKAIERHLEIFNTTTVVVPAILGITAAMEEENANNPEFDESSISAVKTALM
                     GPLAGIGDSLFWGTFRIIAAGVGVSLAKEGNIFGPLLFLLLYNIPAFALRIFGLKYGY
                     QVGVNSLERIQREGLMEKIMSMATTVGLFVVGGMVATMLSITTPLKFNLNGAEVILQD
                     ILDKIIPNMLPLTFAFVIYYMLKRKVSVTKLTIGTIVTGIALHAIGLL"
     gene            complement(28343..29134)
                     /locus_tag="PC494_001856"
     CDS             complement(28343..29134)
                     /locus_tag="PC494_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDF3912358.1"
                     /translation="MLVQATMLAIIAGVGILDGRIFGQSMLDRPIVTGMLVGLVLGDI
                     KSGIMIGAQLELIWMGIAGIGAATPPDVVTGGVLGTAFAILSGNGAEVALAVAVPVAV
                     LAQSLGVLVRIINSYFSQKAVFYAKQADFKKVTIMMWLPVILFFLSTSVPTFLAIMIG
                     ADKVTALINAIPKVILDGLGVAGTLLPAVGFALLMDMLLSKKMSVFFFIGFLLASYGG
                     LDITAIALFGVCVAFVLNFYINNKENNQNPQLAINTLTEGEIDFE"
     gene            complement(29174..29596)
                     /locus_tag="PC494_001857"
     CDS             complement(29174..29596)
                     /locus_tag="PC494_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIA"
                     /protein_id="HDF3912359.1"
                     /translation="MKKFLIATHGELSRELVDTSKLIIGSLTNIEYFCMTTDKSADDA
                     EKEIRSILSNNKDSEEFVVLTDVFGGSVANICTNLLLQGFKFELLTGVNLPMLLSILL
                     LVEEDTKLIVKSGLEEAKNGIVYVNELLENQNKIKNVM"
     gene            complement(29612..30091)
                     /locus_tag="PC494_001858"
     CDS             complement(29612..30091)
                     /locus_tag="PC494_001858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDF3912360.1"
                     /translation="MVSLMRIDDRLIHGQVAYGWATSLGINVILVANDEAKNDQMKAM
                     SLNLAKPSNVTLYIRGVEESGEIVEKFASSKKSNVLVLVKNTKDALVVAKNSGGVLKE
                     INVGGLRYEEGKKKLTDLVAVDDDDINNFKQIGDLGIDIEFRMLPRDKKKQLSDLIK"
     gene            complement(30223..32979)
                     /locus_tag="PC494_001859"
     CDS             complement(30223..32979)
                     /locus_tag="PC494_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDF3912361.1"
                     /translation="MRDEILSFVNECVLFNNFDELKKESGIITEDIVKKFNLSRTQSS
                     RLLNDLVKSDNLIKINSRPVIFLPKNKINDVVGPTKKSIYENLDELKNECKLLKQETV
                     FNSIIGYENSLKEVIEQIKTAVLYPNGGLTIMLTGESGVGKTFLAKIIYKYSVSSNVL
                     EKNSPYNVLNCAQYYNNLELLSSLLFGHVKGAYTGANESRAGLIEQSDGGVLFLDEVH
                     RLNSEGQEKLFTFMDTGTFSRIGENGVIRKARVRLIFATTESLSEFLQTFLRRIPINI
                     YVPNIEERGTIEKRKIVEHFIYEESKVLGLPIEITQITLNAILKIKFKGNIGECKNVI
                     KYACGRAYAKNQRRNGNIFVTLQDLPRNLYIENVDIFQFQSGKSKSIIFSPKQFSIEM
                     SNGRNKRNIIYQSFIKCLDYFDRLEKNEITKEKFSKKSSNLMIRLMDNLVFSNNDENN
                     NVLMELIISIMQDIFRNLEVNNNIKYDGNNVLAFSSYLYLKDESYQLSDEYKALENKL
                     LIYLKKESYKEYSIISKISTLITNRLDMYLNNVDTIIMIIFIKSTIIRMKFNQVNATI
                     IAHGYATASSMANVCNRMLGKNIFTAIDMPIDATIADVSKQMSRYLEGDRIKNGLIVL
                     FDMGSLNLIFEDLKNKINSPMLFIDQISTISALEVGNLLMQGKNIEEIAEIMDEETKP
                     NIQLYYPQKNKEYAIISSCFTGIGTAIKIQHLLSESLIGIVDVKIIPYDYDSLVSMGD
                     KEPVFEMYDVMAIVGTANPNVNGVDFILLEDIISGKGEDDVFRIFSRVVENEKIKNIN
                     DSIVKNFSLIRVIDSLTILDSKKIIERIEEGINAIENIQKKKLSNDKKISLYVHLSCM
                     IERLVRQTEIEEYTDMDLLIKNHHSEVKLIKNAFSVLEKSYSVQIPISEIGYIYNIIY
                     GLPQ"
     gene            complement(33577..34380)
                     /gene="proC"
                     /locus_tag="PC494_001860"
     CDS             complement(33577..34380)
                     /gene="proC"
                     /locus_tag="PC494_001860"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HDF3912362.1"
                     /translation="MKTLGFIGSGNMGSAMIGGIVQSELVKAEDITVSDLSQVALDKV
                     KEEFGVNTTTDSKVAVTNSDVVIVALKPNICEKALTPLKELIDANKIIVSIAAGKTIE
                     SLESFIGSDKKIVRVMPNTPALVGEGMSALCKNSNVTDEELNMIKALFESFGEAEIVS
                     EYLMDTVTGISGSSPAYVFMFIEAMADAAVLAGMPRQQAYKFASQAVMGSAKMVLETG
                     KHPGELKDMVCSPAGTTIEAVKVLEEEGFRAAVIKSIVACIDKSKDMSK"
     gene            complement(34705..37074)
                     /locus_tag="PC494_001861"
     CDS             complement(34705..37074)
                     /locus_tag="PC494_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl radical protein"
                     /protein_id="HDF3912363.1"
                     /translation="MARGTFERTKKLREESINAEPHISIERAVLMTEAYKKYEGSVEI
                     PVLRALSFKHYIENRTLSINDGELIVGEKGDSPNGAPTYPEICCHTMEDLEVMHNRDI
                     INFSVSEEARKIHKEEIIPFWKKRQTRDKIINAMTPEWLAAYEAGMFTEFMEQRAPGH
                     TVCGDTIYKKGFLDLKKDIEARLKELDFLNDLDAYNKKADLEAMAIACDAMVILGKRY
                     AEKARQMAEEETDEAKKKDLLLIAETCDVVPAHKPETYHQAIQMYWFVHIGVTTELNI
                     WDAFTPGRLDQHLNPFYERDVENGILDRDRAQELLECLWVKFNNQPAPPKVGITLKES
                     STYTDFANINTGGINPDGQDGVNEVSYIILDVMDEMKLIQPSSNVQISKKTPQKFLKR
                     ACEISRKGWGQPAFYNTEAIVQELMEAGKTIEDARLGGTSGCVETGCFGKEAYVLTGY
                     MNIPKILELTLNNGYDPISKKQIGIETGDPRNFQSYEELFEAFKKQLHYMIDIKIEGN
                     AVIENICAKHMPCPLMSTIVDDCIEKGKDYQRGGARYNTRYIQGVGIGTITDSLTAIK
                     YNVFDKKKFDMDTLLKALDANFEGYEAILNLVSNKTPKYGNDDDYADEIMQEIFNAYY
                     NEVTGRPTVCGGEYRVDMLPTTCHIYFGEIMGASPNGRLCAKPVSEGISPEKGGDTNG
                     PTAVIKSCAKMDHIKTGGTLLNQRFAPSVVQGEKGLDNMANLVRAYFNMDGHHIQFNV
                     FDKNVLLEAQKNPQDYKDLIVRVAGYSDHFNNLSRTLQDEIIGRTEQTF"
     gene            complement(37079..37987)
                     /locus_tag="PC494_001862"
     CDS             complement(37079..37987)
                     /locus_tag="PC494_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl-radical enzyme activating protein"
                     /protein_id="HDF3912364.1"
                     /translation="MNPLVINLQKCSIHDGPGIRSTVFFKGCPLECVWCHNPESQTYT
                     KQVLYNEERCSKCEACINICPHKAIYKGETKICLDQDKCEFCETCLDYCVNNAREIVG
                     QEYSVRDLVKEIEKDRIFYEESGGGVTLSGGEVMAQDMDFICGVINMCKSKGIHVAID
                     TCGYAKSENYERVAKCADLFLYDIKLIDEDKHIKFTGKSNDLILKNVKILSELGANIN
                     IRIPLIVGVNVDDENLEVKKMIEFLKPLNIQAVSLLPYHNIGKHKYDKIYKKYEGEEL
                     QRPSEEKLEEIKRLFEASNFNTKIGG"
BASE COUNT        12155 a         6770 c         4184 g        14989 t
ORIGIN      
        1 tattgcttat aaattttaag acataaaatt catatattca caacataaaa taaaaatata
       61 acacatctgt aaagaattat aacatcatat ttgtatatat ataaagaaaa acatacaaaa
      121 agtatagaat atatactttt tgtatgtttt tactaattct tatatttatt ttattttaga
      181 ttctaaattt gttaatcttt cctcaacaga tttaatcatc tcttcaaatt tttctttttt
      241 tgctttttct tcttcaatta aactttcagg agcttttgct aagaaacctt gatttgcaag
      301 ctttccatta actctcttta tttcgccttc taactttttc ttttctttag ataatctctc
      361 aatttctttt tcaaaatcaa ctaattcatt aagaggtata aatatttcaa caccatcaat
      421 aactactcca actgcatctt ctggaacatt agatttatct tttgctatct ctacatttga
      481 agcagatgct aaagttataa aatagtcttt accaagctca atagcttcta ttttttcttc
      541 acttgggatt attatcaatt tagctttctt agaaggtggt acattcattt ctgctctcac
      601 atttcttata cttcttatac cttccatcaa taagttcatc atatcttctt cttcagccat
      661 gttatcttct tcattatatt ttggccattc agatactatt atacatcctt caacagtagg
      721 aagatgagta tatatttcct ctgttataaa tggcatgtat ggatgtaata attttaatat
      781 tttttcaaga acataagtta atgtatataa tgctgcagat ttagcatttg catcttctcc
      841 atataatcta ggtttaacca tttcaatata ccagtcacag tattctgacc aagtaaaatc
      901 gtatatcttt tgaagtgcta ttcctaaatc aaacttatcc atgttattag ttgcttcttt
      961 tacaatatta tttgctcttg atattatcca tttatcagct agagttaagt cctctttaac
     1021 actttctcta gtcatgtttt taattatatc ttcatcaata ttcataaata caaatcttga
     1081 tgcattccac aacttatttg caaagtttct agcaaattct actctttcca tatagaatct
     1141 catatcattt cctggggaat ttccagttgt taatgtaaat cttagggcat cagctccata
     1201 ttgctcgatt atctccaatg ggtcgatacc atttcctaaa gatttactca tttttctacc
     1261 ttgagaatct cttactaatc catgaaccaa aacatggtca aatggctttt cattcataca
     1321 gaacatacct gcaaatgcca ttctaactac ccagaagaat attatatcgt atcctgtaac
     1381 aagtacactt gttggataat aataatctaa agcttcagtc ttatttggcc atcctagagt
     1441 agagaaaggc cataatgcag aactgaacca agtatctaag gcatcttcat cttgtttaaa
     1501 atgagtgctt ccacatttag gacacttatc tggcattttt ctagcaacta ctatttctcc
     1561 acactcttga caataataag ctggtatttg atgaccccac cataattgtc ttgatataca
     1621 ccaatctctt atattttcta gccattgtaa ataagtttta tcaaatttat ctggaacaaa
     1681 ttctaattct ccttttttaa gaatatctat agctggtttt gcaagttctt ccatcttaac
     1741 aaaccattgc tctgataatc taggctcaac tactgtatgg catctataac aagttcctac
     1801 attatgatta tgctctttta tcttaattag gtaaccttgt tcttttaagt ctgctacgat
     1861 agcttttcta cactcaaatc tatccatacc ttcatatttt ccacaaactt cattcatagt
     1921 tccatcttca ttcatagtat ttaactgctc aagattatgt cttaatccta cttcaaaatc
     1981 attagggtca tgtgctggag tcatcttaac tgcaccagtt ccaaactcta aatcaacata
     2041 actatctgca actattggaa gttctcttcc tactaatgga agtattgctg tttttcctat
     2101 taaatgttta tatctatcat cttctggatt tactgctata ccagtatctc ctatcattgt
     2161 ctcaggtcta gttgtagcta tttctaaaaa gtcttcacta tcttttagtg ggtactttat
     2221 atgataaaag tttccgtcgt gttcttcatg ttcaacttct gcatctgata aagtagtttt
     2281 gcaatctggg caccagttta ttattctatt tcctctgtat atgtgacctt tttcatatag
     2341 gcttacaaaa aattctataa ctgcttcatt acacccttca tccatagtaa atctttcttt
     2401 atcccaatca caagaatcac ctagttgttt aagctgatta gatatttttc ctccaaattc
     2461 atctttccat tcccaggctc tctttaaaaa ttcttctcta cctatttcat actttgtctt
     2521 gccttcttgt ttttttattc tttcaacaac tttaacttct gttgctatag aagcatggtc
     2581 agttcctgga agccaaaaag cttcatatcc atccatacgt ttccatctga ttaatatatc
     2641 ttgaagtgta tggtcaagag cgtgtcccat atgcaattgc cctgttatat ttggtggtgg
     2701 catcattatt gtaaatggtt ttttatctgg atttggttta gatttaaaat acccttcatc
     2761 catccatttt ttatatagcc tagcctcaaa atcttttggg ttataagttt ttgataaatt
     2821 cgtattttcc attgtcctgc ctcctgtatt ttataaataa attttttaaa tatctttaga
     2881 aataaaaaag agctcttcat cctctttaaa aaggacgaaa agctcgcgtt accaccttaa
     2941 ttccaaagct taaaatacat taacatatca ttaaattatt ggttaatgtt attttatcaa
     3001 ctttgactct caaagaattt aacggttcta accgtctaaa cttacttata gttcagttta
     3061 gaaactccaa agctacattc agtaaatctt atacttagaa aatcttacag ccagtgaatt
     3121 ttcctctctt ttagtagtat ttacttactc ctcttcttct cagtctttaa tattacatat
     3181 tattatatac aaatattatt ctctttgtca attattttta ttttattttt tctgaatttt
     3241 cttaattatg tctattctct tttatatagt tgttatattt taaaatatgt ttttacagtt
     3301 attctgtctt ataatgtcaa taattgcaag attattttat tttaatttta atgctttctc
     3361 attaatttta tattatatta tccttacagt atacctctta ttcgtatttt ttatattata
     3421 tgttttattt tataaataat ttactttatc ttttactata tttaaattta ttataagttt
     3481 tcttgccaga aatttttagg tgttatgttt tctgtaattg gcaatattgt atatcctctc
     3541 tcttttaaga ttcttataat attatttaaa gcatttaaac tttgctcttt ctcatgaatt
     3601 aatactacta attcatctct ttttcttcca taatataata tattacttac tatctgactt
     3661 gtagaagact tccaatcctg tgtatccaaa ttccagtccc aaattaaata atcatttgcc
     3721 ataagtttat tatatgaacc ttctggcata tatggtttac ttccgtatgg taatcttatt
     3781 aattttgaac tctgaccagt tatttcttgt agagtattat tgcatgtatt aaattcccca
     3841 actgttactt ctgggctttt atataactta tgtatatcat gacttacact atgaaaacct
     3901 attgagtttt cttcttccaa gactctcctt acttcttcct tgtggttttt catattctga
     3961 ttaagcatga aaaatgtcgc tttgacatca ttttctttta aaatatcaag tagtgcattt
     4021 gtatattttg atggaccatc atctattgtt atgtatgcta ctttttcaga agtagcccct
     4081 ggaccttttg tttcttcttg agatgctttg tatatgattt ctcctaaagt attactttga
     4141 gaaagcagtt ccagtgtatt ttcacctttt gaacttatat tttcaactgg aacattatta
     4201 attttttcct ccaataatgt tccagttaaa attaaaacag ctataagaaa tatccttata
     4261 aatacatgaa aaacagcctt attatcttta attttcatcc cccatatctc ccttttataa
     4321 aagcataagt ttaagactta aaaagttatt ttttatattt attctctttc ttattacttt
     4381 ttatatctct actaaatatt tttttaacct tttcttcttc tttttctcct aaagattcta
     4441 ctcttttgat tcccaaagaa gttaaaaatt gtaatacatt taaattatca aatggagttt
     4501 ccatattcgt actttcacta tattcatcaa cattcttagt accttcttcc acacttaaaa
     4561 tacgcttcgg acctcctaca cagcctccta cacaccccat tccttctata aatgtagctt
     4621 ctatttcttt atttagaact ttctttagac cgtccatgca ctcttttgtt ccttcaaatg
     4681 ccttttcttc aaattttata tttttgtcaa ttcttctaac tgataactta actgctttac
     4741 ttacacctcc tgttctagca taaactctac ctgaaaggga cgcctctact ctattactct
     4801 catccattat tgctggattt aactctaatg catcaaatat ttcttgcaac tctttaaatg
     4861 taagcacaaa atcaactgca tcttttatat cttctaacat tgcttctttc ttttttgcca
     4921 tacaaggacc tatgaataca actttagcat ctggatttaa aatttttaca gctctcccac
     4981 aagcaatcat aggagaaacg gatggtgata cattttccaa tatctgagga aaactatttt
     5041 gtatcaaact aacccaaata ggacagcaac aactagttat aaagcatcct tcttcgtcct
     5101 ttttcatatg ctcataataa tcatatgctt cttttgcagt aagcatatct gctgccaaag
     5161 caacttctat catatcttca aatcctatct tttttaatgc agttcttaat ttaccagggc
     5221 ttacatcttt cccaaactgt cctacaaaag ctggtgcaac tattgcatat acagggctct
     5281 ttatatcttt taacaatttt atcattggta taaattctat tttatctgaa attgcaccca
     5341 acttacatct tgatacacaa tcaccacaag cactacatac atcttcctca ttacaattaa
     5401 tatgcttact tcttatctta catgactcat cttccttatt attttcatca caatatttgc
     5461 aagcatctga tattacagat attattggtc ttttgacttc atctaaattt acagcttcat
     5521 gtagtgactc ttttaaattt ttatctgtat cttctgtcac atccaatccc atagttaccc
     5581 taattaaatt taccatagta tctttatcaa attttccact aaaataatta tttaaattat
     5641 cctttaaatc ttcatttaaa attttattag gtaagttttc aatatcctct atatcatcat
     5701 tccacactgc ttttacaagt tcgccaaaaa gcttcatttt atatatttct agtattttag
     5761 aattgtcatt tctagtattc ataaaaaata gtacctccat aaattaaact tatatatgtt
     5821 taatatttac aaagatacta ttttttattt attatttaac tactattatt aatatgattt
     5881 atttagcttt ctcaacaact ctatttcaat cattattttc attagatgat agttgaatac
     5941 agggcttttt tcttcatcta tattccagtc tagcttatcc acattatatg ttttcttaag
     6001 gtatttatat gtatgctctt tcaaataaag tttattttca agtaactcta tagactgcat
     6061 atgaaaatgt atttctctac atatccttaa ggcattctca attttttcta tattagtttc
     6121 actcaaacta taatccaact catcaataag ttttgaatat atttcttcta atttttctac
     6181 ttcttcttca aatttctcta catttaaatt ttcttttcta agaattttat cttcgataag
     6241 caacattgaa agttcttcta tctttttaaa ctcatctata acactattta gataatttgg
     6301 tctagcaaca taataattaa caagtactcc aaacaaaaca cccacagatg tatctaacac
     6361 cctatgtaaa gaataataca cagggtcact atttcctaca cctagatgta tagccagaaa
     6421 ggttacacag gcaactacta ctgactttat tttaaacaga ttgcataaat atattgagca
     6481 cattactcct agaccacata aaaatgggtc tccagcttta atgatggcaa atatgaatcc
     6541 tattatacca cctaaaatag taccttccac tctattgatt cccgtcttta aagaaccttt
     6601 tactgtatct tgaacagaaa ttatacatgc taccagagaa taaaacatat tctctactaa
     6661 atagtcacca agaatcatac ataaagtgac actaattcct gtttttatag tcctcatacc
     6721 catcttttga agtttcaaag ttccacctcc taaaaagcac cttatataaa atacgcatcc
     6781 tcatatttaa tatgttccta gtatatcaca attttttaaa tttacccatt aatcatattt
     6841 ttttatcaat tctttcttaa tttagacaat aaaaaaactg ctttaaagca gttttttatc
     6901 ctatctcaac cattttaccc tcaattgcaa aaattatctt ctcacataca tttgttatat
     6961 ggtctccaat tctttcaagg tatcttccta taagtagaag ttttacccct tggtctatgg
     7021 tatttgagtt ttcatgcatt atttttaaac aatcaatttg tacttgttca tacaatccat
     7081 ctacaatatc atctttagtt ccaacatcat aagctatact tgcatcaaat aagattaaag
     7141 cttctctagt ctgagacatc atagacttac attcttttgc catcttagga atatctatta
     7201 gctcttttat ataagcctct ccacctatct tcagcatttc tctagctata tttgctgcat
     7261 aatctcctat tctttccagc tctatagata tattacctaa tgaataaata aatcttaagt
     7321 cccttgccat tggttgcttt aatactatta gctctatact cttatctctt atttcttctc
     7381 ttaatttatt tatttcttca tcatcttcta ctacttttct tgcaccctct aaatccttct
     7441 ctatcataca agtcacagac ttttctattg cttcttcaca tttttccatc ataagcactg
     7501 tttgttcttt taaagtatca atacttatat ctaaactatt attgaccatt gtctaactcc
     7561 tttatagtta tatattttaa ccaaatctac ctgttatata gtcttctgtt cttttatcta
     7621 caggagtggt aaacatagtt tttgtatcgc taaattctat aacctctcca tttaagaaaa
     7681 aagctgtttc atctgatata cgagcagctt gttgcatatt atgtgtaact atgactattg
     7741 tgtagtcttt ttttaaatcc tctataagtt cctctacttt taatgttgaa attgggtcta
     7801 aagcagatgt aggttcatcc ataagaataa cttctggtct catagcaatt gctcttgcta
     7861 tacatatacg ctgttgttga ccaccagaaa gtcctagtgc agatgattta agcctgtctt
     7921 taacctcatc ccaaatagct gcacctttta agctttcttc tacaatttta tctaattgct
     7981 tcttatctct tagtccatgt gtacgaggac catatgccac attatcatat atactcatag
     8041 gaaatggatt tggcttttga aataccattc ctactttagt acgaagattt ataacatcat
     8101 ctgaggtata tatgtcctct ccatcaacag aaatgtttcc tttaattgtt acatcttcga
     8161 ttaagtcatt cattctattt aacgttctta taaaagttga ttttccgcat ccagatggac
     8221 ctattaaagc agtaacctta ttctctttta tatccatatt tattttcttt aatgcttgct
     8281 tatcaccata aaataaatcc aaatctttta cactcatttt tatcttatcg attaattcca
     8341 ttattcacac ctcttaaatt taataattag ctttatttaa tttcttagca acaaatcttg
     8401 ctagcatgtt tagtgctaac acaattacta ttaaaacaat tcctatactg gctgctgttg
     8461 ctatatctcc actctcttta gtcagtaagt atgagtgtac agttaatgtt cttgcactat
     8521 caaatattcc acctggcatc ttggctacag tacctgctgt aagtaatatt gcagctgatt
     8581 ctccaattat acgaccaact gataagatta ctccagataa aattcctggt attgcacttg
     8641 gaagtactac cttatataaa gtttgaaatt ttgtagctcc taatgccaat gatgattctc
     8701 tataagcttg aggaactgtt tttaaagctt cttctgttgt acggattatt actggtaata
     8761 ttattattgc aactgtaagt gaacctgcaa ctatggaata tcccattttt aatgtaacta
     8821 caaagaaaat tcctccaaat aatccatata ctatagatgg tatccctgat aaactttcag
     8881 ttgcaaatct tatagctgta actgcttttc cttttttagc atattcttgt aaatatatag
     8941 cagccaatat tcctatagga gttgctacaa ctatagaaac tactactgta tataatgttg
     9001 taattatcat tggaagtata ccaccatcac ctgatgctga ataattgcta aataagaaat
     9061 taaaattcat gttgccaatt ccctttataa atataaatcc cactataact actaatgata
     9121 ctattgtaaa tagtgctgat agatatacta atgacttcaa tagattctct ttgaactttc
     9181 tcatcttaat ttaccgcctt atttgaaagt ttatttaaaa ctaagtttaa aattaatata
     9241 aatgtaaaca atactactcc agttgcaaat agcatttctt gatgtgtacc aaatgcgtat
     9301 cccatttcaa gtgctatatt agttgtaagt ggtcttacac tatctgttat tgcagttggc
     9361 ataactggtg agttgcctgc aacaagtatt actgccattg tttcacctaa agctcttcct
     9421 actcctaaca ctactgcggc taatactcca gattttgcag caggtaatac aactttgaat
     9481 attgtttcta tttttgatgc accaagtgct aatgaacctt ctttgtatgc ttttggtact
     9541 gctcttattg ctgtttctga tacagatatt attgttggta acatcattac tgctaatact
     9601 attactattg ctaacaaact ttgacctttt ggaagattaa atatactttg tatagttgga
     9661 actatcactg caagaccaaa tacaccatat aatactgaag gtatacctgc taaaagttca
     9721 actgctggtg acattatttt tgctaatctt ttaggtgcta cttctgctat aaatacagag
     9781 gttaatatac caacaggtac tcctataaca agtgctccaa gtgttgcaaa tattgatgct
     9841 actatcatag atgatattcc aaatttattg gcagaaggaa cccaatctgc accagttaaa
     9901 aagtctataa atgaatatcc ttcaaatata aatggtctta atcctttata aaatacgaat
     9961 cctattatca aaagtaaact tgcaactgct actaaagcac taagtagaaa aatatttttt
    10021 gctacttttt caattacgta ttttgtctta ttgccattat tgtcattttt ttctaaacct
    10081 actaatctag attttactat cataataccc tcccattaaa atatacttat caattttcgt
    10141 tctgtattca aaatttaatt ttttataatt cgtcttcatc aaatttccta tacttttatt
    10201 ctactttttt taagttaaat ctatattagg attaagttaa gcaagtgtaa aattatattt
    10261 actttttaac attaatttta cttttaaaac tatatttgac atttacttta caatatactg
    10321 ttgtttctct atattaaaat agcagatata ggtaataata cagtttatgt ataatttatt
    10381 acctatatct gctattaaga tttgttaact aaatttaact tttatactac atatataatt
    10441 attgtatcct ctagtttata tcactattat ttccatcaaa ttgttacgat acttgatgtt
    10501 tgcaataggt acgaatagcc aaaaatataa aaataggtat ttctataact gagaaaaaca
    10561 gtataatgtg tggtgtccaa aaactcatac ctcctaagtg taagaaatta aatgatgtca
    10621 tttgatataa taaactaatc ttaaaaccaa ttccccctgg cggtaatagg tatccaatcc
    10681 aactaacacc tattcccata ggaattaagc aaatagaaaa agcaatcagc atagaagtaa
    10741 gagaatcctt acattttgca gataaaaata atgttaaact aaccattgca agtattgaaa
    10801 ttagaccacc aatagctata agaatctgtg cttgtagtaa atttatattt actagactaa
    10861 ttacagaaaa caacatttga aatgaggttt tcaagcattc agtaccaaaa gctaaatcag
    10921 aaattgccaa atggatagaa atacatataa caaacattat tataaatata gaaaatagag
    10981 ctaatatttt agtaaacgct agacgaatat gtccatgttt cgtacaacga aggatgctat
    11041 ctgattgtgt ctgatactca ccagaaaaag taggtgcagc aattgcaaca catataatta
    11101 ataatataaa aatataaaat attatataat cgaaagcatc tttagaataa cctgggtata
    11161 tctcaaatgg agtatctact tttctataaa gttcttgtgc tttcatttgt gcactggaag
    11221 tttgtcgttc aatcttcata atatcattta aatgagtttt gcattgttca taaaaagaat
    11281 ctaaatcatt tgtatttatt tctgataatt ctgttgcaaa tcctgtttct gaattagcaa
    11341 atgcttcagg aagtctattc aacaatgggc gtattggtaa aatactttta gaataaacat
    11401 ctagtggaaa atcttcacta cctactttac catacttttc ttctgttttt ttccatatat
    11461 ttaaagcatg ctttaatttt tttggtgtta caactccact actaatttca ctattattag
    11521 cataaattgt ttttttatat ttaatagcat ctaaaccact caattcaact accttgccat
    11581 tatcatctaa ataattgata ccctcataag taattggaag aaaagccatc aatgcagata
    11641 aaaccaacgc caacaataat aaaattaatg tacgacgtga gtgcaacact cgtttaattt
    11701 ccaaataaaa aatacgcatt tatttcccct ccttactata aactgcttct ggaaataacc
    11761 ataaatataa atcttctagt cgtggttcaa cagcaataga gttatcaatt tgtgactttt
    11821 ctgccaagta acgaatagat acttgattgt ttttttcact acgctgattg attatacgta
    11881 aattcatttc atattttgaa atatctctat ttgatataag acattcccat actttgccct
    11941 ctactttctt aaccagttta tcggttgttc ccacatcaag aatttttcca cttttcataa
    12001 tagcattttg agttgatatg tactcaatat cagatacaat gtgagtagat attaggacaa
    12061 cacgattatg agaaaattct gaaataaaat tacgaaatct cactcgctca ccagggtcaa
    12121 gccctgctgt tggttcatcc attataagga ttttagggtc atttaacatg gcttgtgcaa
    12181 ttcccactcg tcgtttcatt ccaccagata atttaataat ctttttattt tttacatcag
    12241 ataatgtaag gatttccaat agattattaa tttttccttt tacttctctt ggtggtacat
    12301 ctttcaatgc tgctatatat tctaaataat cttttacaga aaaatcctgt gggaaaccaa
    12361 attcttgtgg taaaaatccc agtaaatttc tgtactcagc acccattgta taaatatttt
    12421 ttccattata cagaattttg ccattggtag gtttcataat atctgtaata attctcataa
    12481 gggtagtttt acctgctccg ttcgctccta gaaatcccca cacacctggt gttaaagtaa
    12541 ggcaaacatc ttctacagca attttatcct taaatttttt tgtcacatgt tcaattttta
    12601 attccatatt tgaaactcct ctctttatct acttacctgc aaaaacaaaa gtgccttgct
    12661 cagtatttat tttactaaac aaagacactc atagttttaa tattaaatag ataatttctt
    12721 aagaaaatcc taatatttga tttatatttt actaagtaga tgtaggaagc gatatggtaa
    12781 atgttgtgac ttcatcttta ctttgaacag taatatcacc accatgcaaa tttataattt
    12841 ccttagctat agaaagccct aaacctgcac cacccatatc agattttcta gcttcatcta
    12901 aacgattgaa cttttcaaat atagcagaaa gttgttcttc cggaattgtc tgtccataat
    12961 ttctaaaagc aatatctacc ttgctgtctt tatgaaccgc tgagataata atttctgtat
    13021 taggataact gtaagcaata gcatttttca agatattatt aaatactctt gcaagttttt
    13081 cagaatctgc ttttattgtt aaactttcat ttgcttttag aatggctcta tttccttttt
    13141 cagatagcaa tgggtaaaat tcatccttta actgaagtaa catataatat aggtctactt
    13201 tttcgaaatt aattttgatt tgattagaat tatatcgtgt tatttcaaaa agttcattga
    13261 taagtttttc taaatattgt gctttgtcaa gtgcaacttc agtatactta gatttttgag
    13321 aattatccat attaggtatt tcttttaata agctcaaata cccaataact gaagtaagtg
    13381 gtgtccttat atcatgtgct agatacatca caaggttatt ctttttattt tcagcctctt
    13441 tcactgcttg ttgacttaac aaaacagaca tcttaatttg gttcatttgt tgctctattt
    13501 cttttaatgg cttagatagt tcaaccaatt catcattttg ttgataaata gtatgtgttg
    13561 cattgatgat ttctcttaaa taattccatg gttttttcca ataaaaattg aaaatagtga
    13621 tatatccaat tataaaaacc aaaaaaaata atacatctct tctcaactta agccatttaa
    13681 caagaggatt tgaaaaattt gaaaacgtat aatcagccat aaacattaaa accaatacta
    13741 tacctgtata gatagctaac attatatata atttatactt taaatacgcc tctgtatttt
    13801 tttctctttt tataaattta tatttatctc ttagcttcct ataagtaaaa ttattaatct
    13861 ttttcataat actacatccc ttcttgacaa gaaaaatatg tgtcaaatct tgtaaccaac
    13921 accccaaatt gtttttatat attttgcttc atctacagta tcacctaatt tttcacgaag
    13981 atggcgaata tgaactgtta tagtattgtt acttttattg taatattcat ctttccagat
    14041 aacatgaaaa agattttctg aatttaccac agagccttta tttttcaata atacatgtag
    14101 aatagaaaac tctgttggag taagtgaaag agctttacca tttaaatggc attcatatgt
    14161 ttgggtattc aattccagac ctaaaaaaga aaaaatatgt gaaagttctt caccagattg
    14221 taaatttcca ctgtatttct tatatcttct aatctgtgcc ttcactctag caacaagttc
    14281 caaaggtcgg aaaggtttag taacataatc atctgcacct aaagttaagc ctgtaatctt
    14341 gtctgtttct tcatccttag ctgttaacat aatgattgga taggtatatt tttctcggat
    14401 tttttggcac aaagaaaatc catttactcc tggcaacata acatctaaaa ttgcaaggtc
    14461 aaattcattt aaattaatgc agtttagtgc atcaagacca gaataaaatt tataaacaat
    14521 atagttttca tttgtaaggt agacttctat taaatcagct atatcacgtt cgtcatctac
    14581 aactaaaatt tttccactca tagactttaa acatcctttc tatatatatt tatatatatt
    14641 atactaaatt taattttttt tatataattt tttacattag aatttattaa gaaattctta
    14701 atcttattat ttaactattt tattatttaa tatatattaa aggtaaaaaa taatatataa
    14761 atttagatat acaatttatt tatcttttca aatataatct ataaaataat agttctgtta
    14821 cgcatttttt tatataataa aactgactgt aatttaactg gcaaagtcta gaagaatagg
    14881 ctttatcaat taaattacag tcagctattt tataataatt tagtttagat atcgttagca
    14941 tttcacattt ataacaatta ttaatgatat taatatattt attattcctt attaaaataa
    15001 tatcctgctc ctcttattgt tataattttc tgaggatttt tataatcttt ctctattttc
    15061 tttcttaatc cattcactgc aactaccaca ctatagttat cctctaagta ttcattcatc
    15121 catacatgtt catatatctc tttagtagtc aaagtctttt caggattctc tataaaaaag
    15181 tttaacaact tattttctgt tggagtcaat tttattattt tatcttctaa ctttattact
    15241 ccactagttc tattatattc ctctaatttt gtattatttt cattattatt tacatatgag
    15301 ttcattcttc ttaaaatagc ttttactttt gcatataata tttctaaatt tagaggcttt
    15361 attaagtaat cgtctccacc agaatttaaa gcatttaaaa tgctttggtc ttcatttata
    15421 taagtcatat aaacaattgg acaagtagtt acatttctaa tttttttaca aagagtccat
    15481 ccatcaccat cacttagaat tatttctaaa aatattaaat catatttatt gctaaatatt
    15541 tttccaatag cttcttcaca attatatgct aaatctatac ttattccttt ttcctccaga
    15601 aatcctttta gcttctggca attatccttg tctccatcta ttatcaatat cttagtttgc
    15661 attataatca ctcccaaata tcattattct tttatattaa ataagctatt attataaaaa
    15721 acatagactt aattttattg taaaaacagt tccttttcct agttctgaat ctacaaatat
    15781 ttctccacca tgctctctta taatggattt gacaatatat agccctaacc cttgcccttt
    15841 tggctcatta ttgtctcttt ctgtaaagaa tctgtcaaat acctttggta tattttctgg
    15901 aggtatacct tttccattgt cagaaatttt aataattgca aatccatctt ctttatccat
    15961 tgataaaatt atctttccat caaatggagt aaaggtcaaa gcattataaa ttaaattctc
    16021 aaatgctctt gtaagcatct ctttatttat ctttgcatat atttttttct ccaatacgta
    16081 agtttcaaag tttacaccac atgcttgtgt atctggcaaa ttattttcat atatctcttt
    16141 aataaaatta ttcagacata ttttttcact aataccaatg cttttatctt gtgatgtaaa
    16201 ttcttgcaaa ctacgtactc tattttgtac ttcatttgac ttttgattta tagcataaag
    16261 ataggttctt gtctcttcat ctacatgaat attaccaacc tttatcaaat ctataaatgc
    16321 ttgtatagcc gaaacaggtg cctttaaatc atgtgctaca tctgccaaga atcttttacg
    16381 ttcatttaac aatgttgtaa gttcattagt tctcacttca acttcatgtt caagattcct
    16441 tgtaagtttt tcattctctt ttattattat tctattcctg tttatcatca taacagaaaa
    16501 taaaataaca attacaaacc cacaatattc tgtttgccac cctgtaaata taggctcaaa
    16561 tctattactc gtaactgcat caaataatat gctaattcca aaaacagtgt ttactgaaac
    16621 taaaatataa gaacttatat gctcagagca tgtcttttta tatattgaaa ccagcgaaga
    16681 cattaatata tatataaata caatatattt atatatgtct attaacttcc catatatgtt
    16741 gacaaagtac atatcatatg gaagaagaat aattggtatc actatagata tgatactcat
    16801 tgtaattcct aatggtaaaa ttaaaaatct gtacacttta ttttcttcta ttttggatat
    16861 acttccattt atacaaataa tacataaaac taccataaaa tatgacaaat cttcaaccgc
    16921 atatgtaaag cttaccaaag gcagtcctaa caaatgtaca aagggatagg atacatggat
    16981 ggcaaagaaa acacacatac atccaaaata taagtaaatt ttacttttgt ttgaaagaaa
    17041 ccatacggac aatgaaaata tagctattgc aaaagttgtg aagcaaatta tactataaaa
    17101 aagtaatcga taaaacatca tattacttat gtcctttgtt tctcctaatg caggcggata
    17161 atacaaacca ctataataat gtgaaaaatt cgatacattg attataattt ctgtattttt
    17221 ctttgcaata aaacttacta ctgaattttt aattttgggt ctatattttt ctgttcctac
    17281 atctcctaat ttagaaacca tttctccatt tatccatact tcacttgcgg aaaaaatctc
    17341 aggaagctct aaacttagta gcttatcctt gccttcattt tttattctca tacgataagt
    17401 agcattccca tatggtgact gattcccttt tctcatagaa aaatctggat attgacctat
    17461 aaaaacatat tctggtttta tatcttgctc tgtaaaatca ttcggtttaa atattttatg
    17521 attataaaac tcccagtcat ctatcaaaaa gacaagtttc cctttagtga aagtatcatt
    17581 atctatagtt aaaattccat tacttgctct aatagactta tatgtatatt tattatcata
    17641 tttatacaga atatttaatc ctgttattgc caacagagag actatcaata caatgagagt
    17701 tccttttagt atattatact ttttcattgc atcaaccaca tctctttcat agtcgtatta
    17761 aataaaacaa gaactattta ttaattacag tatctcactt atggtacaaa cttatatcct
    17821 tttccccata cggtttgaat gtattgatgc tccctgctta aagaattaat tttttttctc
    17881 atctgtgcaa tatgaacctg cactgtatgt tgatctccaa tatcaggcat tttccaaact
    17941 tggttatata tctctatctt tgaaaatact tgttctttgt tctcagctag aaacaataat
    18001 atttcaaatt ccatagtagt taaatctata ctttctccat caaaagttac ttttcttgaa
    18061 tttacattta ttactaacgc tgaaaacttt aacacattag gaactgatgt aatatttttg
    18121 tactgcctca tacgagcata tattctaagt tcaagttctt ttaaactata aggttttgtt
    18181 atataatcat cccccccagc taaaaatccc cgaacttttt cttcttcatg ctcataatta
    18241 gataaaaata ttataggtat gttaaccttt tcttttatat cattgcacat tttatatcca
    18301 tctatatctg gcaatgaaat atccaaaatt atacagtcta aaactatact ttctactata
    18361 tccatagcat ctttagcagt ctctgatgta tatacattaa aacctatatt agaaaaataa
    18421 atttgattta tgtttaaaat atcaacatca tcatccacaa ccagtaaatt atacattaca
    18481 ccactccatt caaaggtatt ttaattataa ttccaagttt tataattatt acaaattata
    18541 atgttttatt ttcatatata actggtatta ttattttata atatctttac aaactagact
    18601 ataatactta agtatttttg aataattctt gaatattgta ttaaacatta agattcatta
    18661 ttaaatacta attaaagtct ccgattgttg gagaatggag cttaaagtca ttttcacgta
    18721 taaatttatt atttttctag aaacttgtct attggctagt ttgagtattg atttatatga
    18781 tttatatggt tataatataa aataaattgt attattttgg taaatatatt gttacaaaag
    18841 gtttatattc tgcatctcaa tgtttataaa aactttattt tcttattata atactattat
    18901 tcttttaaaa aaatttccct tttccaacaa atggctactt taaaagccaa aattttacct
    18961 atcaataaaa atcttaacga ctaatactct tattttcaaa ttttgcaaca tttttgttaa
    19021 ttttaaaaca aaaaaagact atgcaatata aaaattatat tcatagccgg ttgcaccact
    19081 aactccatat atctccagat gcccaataat aagatatact tctcagtttc taaaatattt
    19141 ttattaaaaa tcttttatat attttcataa atttcttttt tattctaaca ttgtaatatt
    19201 attttgtcaa tatttccata ttcttagaga taagatacta aaatacctat tttatctaaa
    19261 gatatttata tttctacatt caataataga caataccctg caagttaaag catcattttt
    19321 atgagcttat ctcacagggt attatatgtt tactttatat tataactctt gttattgatt
    19381 aactttaata aatccttttt ctgaaacaag tgcttgtcct tcatcactta atatataatc
    19441 tattaaagct ttaccttttt ctgacaaacc atcttcttta ttaactaata taaatggtct
    19501 tgatattgga tatttattag ctattacatt tgcatcagtt gcttcaacat catttatttt
    19561 taaactattt actttctcat caacatatcc aaatgatata tatcctatag cattttcatt
    19621 tccttcaact gtagttttta tatttcctga accatcactt atttgtgcat ctttagttag
    19681 ttcttctgaa tcaaacccta caatttcttg gaatccatct ctagttcctg aaccttcttc
    19741 tcttgatact attactattg gtgcatcatt tcctcctact tctttccagt tagtaatctt
    19801 tcctgtatat atacctttaa cttggtccat tgtcagattt tttactgagt ttgcagtatt
    19861 agttatcaat gctataccat ctattgctat tttagtttcc tttaatccag cacttttttc
    19921 ttcatctttt aaatctcttg aactcattcc tatttcagat gttccttcta tagcattttt
    19981 tatacctcca gaagaaccaa tctgttgtac ttctacacta acaccttgat ttttttcttg
    20041 aaacttttct ccgatagttt ccataagagg acctattgaa gttgaacctg aaacagaaac
    20101 tttgcttgaa tctcctgaat cacctgaacc tcctgagtta gaactacatc ctactgctaa
    20161 agctccaact aacattgtac tagctaaaag aacgcctatt ttctttttaa acattttact
    20221 tacccccgct tatattttaa ttttttgttg tcatttttct atattttaat aatacagatt
    20281 ctttgttaaa tgaatattag agcagggtta agtaaatgta aatattgtta aatacatgta
    20341 aaaacttaat tttatatgat ttattcttaa ttagattaac tttttaaagt tactttaggc
    20401 agatataaac ataatacaac tcatattatt agaagtcttc attgaagcta tcaacctatc
    20461 acatcctata attctttttc tagtttatta actaattcag caaatacatt taaggcttcc
    20521 tctatagatt cttttttcgt catatctaca ccagcagatt ttaattgttc tagtgggtat
    20581 tctgaccctc cactttttaa gaagtttata tatctatcta ctgcagtact tccttctgaa
    20641 agtatctgtt gacttaaagc acttgcagca gaaaaccctg tggcatactt atatacatag
    20701 aagtttgaat aaaaatgagg tattctcgcc cattctattc ctatttgttt atctactatt
    20761 gcagattttc cgtaatactt ttcatttaat ttgtagtata tattagtaaa ttcatcagca
    20821 gtaagtggtt ttccactctc taccctttga tgtacaattt tttcaaattc agcaaacata
    20881 gtttgtctat gaactgtagt tctaaattgt tctaaataat aatttaataa gtatatagtt
    20941 tcatccttag acttagaatt ttctaataaa taatttataa gaagtaattc atttaatgta
    21001 gatgcaactt ctgcaacgaa tatcttatag tccgaatata aaaatggttg acttgttctt
    21061 gaataatggc tgtgaacaga gtgccctaat tcatgaatta aagtgaatag agaattaagg
    21121 tcatttttat agctcattaa tatataagga tgtgaatcat aacttcccca agaataagct
    21181 cctccttttt taccttcatt atcatataca tcaatccacc cttcatcaaa agcacttttt
    21241 atgaccttca agtattcttc tcctaaaggt ttaagtgcct ctaatatgat atcctgtgct
    21301 ttatcatatg gtatatccat gtcaaattta tctgtcaaag gaacatacaa atcatacatg
    21361 tgtatttcat tcaatcctaa aaatttcttt ttaagctcaa catatttatt tagattagga
    21421 atacttttat ctatagctga tataagatta ttgtaaacat ctaaacttac atcatctgaa
    21481 aataaagacg cttctattgc tgaattatac tttctagttt ttgcgtaaaa tatctctgat
    21541 tttattccac cataaagcgt tgaggcaaat gtatttttat atttctcata tgttgaaaat
    21601 tcaccttcaa aagcgtcttt tctaactcta ctattcttac tttttataaa taaagagtag
    21661 tttgaatgag aaagcttaac cttattcccc tcctcatctt ctatctcagg aaattccata
    21721 tctgcatatg ctaacatatc gtatacattt tctggaattg tcgataattc tgatgtagct
    21781 gcaagtattt cttcctctcg ttcactcaaa gtatgtggtt tatctctcaa tatatccttt
    21841 atatattttg tataaaagga tagcttctca tcttttaagt attcacttaa cttattctct
    21901 tctatcgcca gtatttctgg aactatataa gaagtagcca cacctaaatc agtagataac
    21961 atttctgtct tagtggctct tccttgatta tcattaattc tagtatcttc atgttgtttc
    22021 atatgagtat atacatataa attttgaaca atcctagatg cattttcaga gatatttaat
    22081 actttatata agttctcctt actctcagaa agcttccctt tatattcttt tacttcttgg
    22141 ataagatttt ttactttact tatgtctttt tcaatttcct ctttactgga gtacatctta
    22201 tctatcttcc atttgtactt ttcttctatt gtacttctat cagttcccat atcatacacc
    22261 tctattttaa tttgttttat attttattca ctttacaaaa tatattgtat atattttagt
    22321 ccaaataatc tacatttatt actccttcta tcatatttat ttctttcata acgtcgtgta
    22381 agtgtattct cttagcataa gatacaaaaa aattaacctt ccagtattct tcattacgac
    22441 attctatttc catatttctt acgataagtt gatttttttc aaatttatca tataaaaaag
    22501 gtatagaatc caaattgctt aattttaata tcaatacatt cttttcttgg ctaaataaaa
    22561 acgtattgat tatcctaagc acaaataatg ctatcattac aaataatcca cctagaattg
    22621 ccaattcata ataaccatat ccaactgcta taccaataca tgcagttgcc cacatcccag
    22681 cagctgtagt aagccctttt actccacctt tattttttaa aattgctcct gcacctaaaa
    22741 aaccaattcc agataatact tgagcaggca ttcttgctgg gtcagcattt gtatacaaat
    22801 tataatcaaa gaataattga atcgaagtta ttgaaacaat acaagaacct attgcaatta
    22861 gtatatgtgt cctaaatcct gcaaactgtc ttattttttc tctctctaag cctattattc
    22921 ctcctattat tagtgctaat agtaacctta ttgctatctc cttacttcct atatcaatca
    22981 taatataaaa ccctcctgac ttaattacaa cttatgtcct ccagataatt tacacatcag
    23041 aaatactatt ttatatctta atattattat taatatatgt aaaatatagc catctgttaa
    23101 tttttgatac aaaaaaaccc acaactgtgg gctatttgct taggtacatg tatttattta
    23161 ttaatatatc tattttctta cttgattcta ctaactcttc ttgaaatatt tctggatatt
    23221 ctatgtatgt atttatctct tccctaactg cttcaatctc attttttaac gcttctaatt
    23281 cattgttcgc cataataatc accactatta caaatttgta tatttttata tacattttat
    23341 caaacaatat tatattttgt caatattatg tcaataaaac ttactataaa aatgctttaa
    23401 tttaggtatt gtatacctgg atactaagcc tacaaacata ccagttacta atgatgccat
    23461 taacataaat ggtaagtacc ctatagcaag tatattttca atgattaaac ttgcaactat
    23521 taattgacct atattatgcc ctattgcacc tataatgctt atccctatta gtgataaatc
    23581 ttttatttta ctcgctaaat acataaataa aagacttaga taagctcctc ctatactaaa
    23641 tagtagatat gataaagggc ctgcaaatat tgatgacaaa attaccctga tagtaacaat
    23701 tataacagta tctttgacac ctaacaacat taatgaaatt aaagttataa tattgctcaa
    23761 acccaatttt gcccctggaa atataactat aagaggattt ggtatatatg tctctaatac
    23821 atataaagct aaactatacc ctatcataag acctaaaaat gtcatttttc tagttttcat
    23881 taagttaact cctccaaatt ttatctatca tcttacatta taatacaaaa tatataaaaa
    23941 cacctaattt agactaaaat atttttaatc tatttagaat aaatattagt tatttcaatg
    24001 tgcaattacc tctataaatc ttgacttttt gtatcatact tgttacaatt ttaatgataa
    24061 tgaatttcat taggaggtgt taataatgac tgtttacgat ttaaaaatag gagaaaaagg
    24121 atttattaat agtatagatg gagatattaa attatctaaa agattgcttg cacttggatg
    24181 tataaatagt actgaaatag aagttaaaaa ggttgcccca cttggagacc caattataat
    24241 tagatttaga ggctttgacc ttgcgattag aaaatctgat gctaaaaata tttctttaca
    24301 ataatagagg aggagctacc cgtgattaat gtagcattat taggaaaccc aaatgtcggt
    24361 aaaactactg tttttaatct acttacaggt tcaaatcaat atgtaggtaa ctggcctggt
    24421 gttactatag aaaaaaaaga aggatttctt ggaaaagaga taaaggttgt cgatttacct
    24481 ggtatatatg caatggatac tttctcaaat gaagaaaagg tttctaaatc atatttagaa
    24541 aatgaagatg ttgatgtaat agtaaatgta gttgatgctt ctaatttatc aagaaacctt
    24601 tacttaacaa ctcaacttat gcaatttaac aagcctatag ttatattgct gaatatgtta
    24661 gacattgcag aatctaaagg agttaatata gatgccaaaa aattaagtga agaacttgga
    24721 gtaattgttg ttccaattat agcaaaaaag aaaaatggtg ttgataggat agaagaagag
    24781 attaagggag ctacgcaaaa agcttttata tatcagaaaa actttggaag tgaaacagaa
    24841 acatataaaa aattagaatc cattttatca agatgtacaa aaactacata tacacaaaag
    24901 aaatctatca gtgataagat agacaatata gtcttgaatc ctatattagc atatccaata
    24961 tttattggtg tattgttcct cttatttaaa tttacctttg actgggtcgg aggtccacta
    25021 caagagggat ttgctagtct tatagaggct tatatttctg cacctgttag tgatatgtta
    25081 tctaactcta gcccatggtt taaatcactt atagttgatg gaataattgg aggtgttggt
    25141 ggtactttac cattcttccc tttaatattt acattattct ttggtatatc gttgtttgaa
    25201 gatagtggat atatgtcaag aacagcattt ttaatggata aagttatgag aaaggttggt
    25261 ctatctggta aagcttttat acctatagtt atgggtatgg gatgttcttc tccagctata
    25321 atggcaacta gaacattgga aagcgaaaaa gatagaagag ttacagctct tattgcacca
    25381 cttatgactt gtggagcaaa gctacctata tatgcactat ttgtagctat attctttcca
    25441 cataatgctg ctttagtaac tacatcactg tatttggtgg gtatagttat ggcaattgta
    25501 gttgcattat tcttaaataa aacagccttt aaaacagagg ctgaaccatt tatattagaa
    25561 ttaccagaat atagaatccc tactatagat gcacttatta aaaatacttg gaataaatca
    25621 aaaggtttct tgataagagt tgttactgtc atgtttgcaa tgtcagtcgt aatttgggga
    25681 ctttcttcat tcaatgtttt tggatataca gaagatataa atgtaagctt cttggctact
    25741 ctaggtcata ttatatctcc tatattcaaa cctcttggtt ttgatgattg gagaacttca
    25801 gttgctattt taagtggtct tggagcaaaa gaaatcgtag taaactcttt aaatatacta
    25861 tatggtaatc taactgttgt cttaccaaca atatttaatg gagttactgc atatacattc
    25921 ttgatattta ctgctttata tactccatgt atagctgcac ttgcaactat gaaaaaagaa
    25981 tatggcaata aaatgatgtt tacatcattt gcatatcaat ttatactagc atggataatg
    26041 gcttttatag ttaaaagtat aggtggagta ctatttatgg gtaattcaat aatagaagct
    26101 ttgataggtg gaataattat agtccttgca ctctttattc tgtttaataa attcaagtct
    26161 acaaaaaacg gaaatgtctg tagtggatgt tctatttgtt ctggatgtcc aagtgctaat
    26221 tcttgctcaa gtaaggaaga cagcaataaa aaaaataatg cacactaata tataaatatt
    26281 ttagtttaaa ataagataaa agtgggtgtc tcaaaattaa ctttttagtt catgaggcac
    26341 tcttttttat agaaaatcaa atatattttc atcatttcaa cagtaaaaaa gagcttatct
    26401 agtaaaaaag aggcttatct ctattttgag acaacctctt tttttgttac ttattcagtt
    26461 tcttgctacc taacttcatg tggaacctag tatcttttgg aacacttggg tctacacctc
    26521 ttaatgtagg tatttcccca catattagtt gtataggtac tataaaatta aatgtttgat
    26581 agtaaggatt atctgtgata tcaatcttta aatttttatc attttctgta acatctctac
    26641 ctatagcaaa tacattttcc gtccaaccag aaagtacatc aatcatctta gttactctag
    26701 gttcttttcc tgtatctagt ataaatatag tagaatcact atttatagca ttatatatac
    26761 catgtataaa ctcttcaaac tcatacccag ttacaggtat tctcattgtt tccaataatt
    26821 ttaatgctgc ttctaatgta tctccatata tatcagagtg acctattatt cttatttctt
    26881 tagaattaac taacttttct ttgtttcttt caatccattg tttagagagc ttatacactg
    26941 cttcaaatct attaattgcg tctaatatct tatttatttc ctcattgtac ttttcactag
    27001 atattatacc tttttctcta gctatttgaa gacctaataa cattaagttt aactttgtac
    27061 aataatatcc ttttgtttta gctccagatt tttcttcacc acaatttact gttaatatat
    27121 aatcagaaat ctcatctatt aaagcattct tacaacctgc catagatgct attttacagc
    27181 ccttatcttc agctaacttc atagcgttgt atgtagaata actactccca ccttgagata
    27241 cacctactac tagggtattt tcattatcaa acttgaatgt atcttcagtt atcataaatg
    27301 gatacatttt cacaacatct atatctaata aattttgtaa atatggttgc acttgcactc
    27361 ctgagtgata gctagtacct gaacctgtta ttataatctt ttttagattt gttctcttaa
    27421 cttcattaaa taagctatct gcattagata taatttctct cattctaact ggtgtttcta
    27481 acatataatc ttgtattgtc attttataca ccttccttat ctatatattc aataaattat
    27541 aattaatttc tataacaaac ctatagcatg taaagcgatt cctgttacta tagtgcctat
    27601 agttaatttt gttacactta cctttctctt taacatgtag tatattacaa atgcaaaggt
    27661 taaaggtaac atattaggta ttattttatc tagtatatct tgtaaaatta cttctgcacc
    27721 atttaagttg aatttcagag gagtagttat actcaacata gttgcaacca ttcctcctac
    27781 aacgaataaa ccaacagttg tagccataga cattattttc tccataagtc cctctctttg
    27841 tattctttca agagaattta cccctacttg ataaccatac ttaagtccaa atattctaag
    27901 ggcaaatgct ggtatattgt ataatagtaa gaataatagt ggtccaaaga tattaccttc
    27961 ttttgcaagt gatactccta ctcctgctgc tataatccta aatgttcccc agaataatga
    28021 atcaccaatt cctgcaagag gtcccataag agctgtttta acagcactaa ttgaactttc
    28081 atcaaattct ggattattag cattctcttc ttccatagct gctgttatac ctaatatagc
    28141 aggaactact actgtcgttg tattaaaaat ctccaaatgc ctttctattg cttttgcttg
    28201 attttctttc ttattgtata gcttctttat tgcaggtaac attgaataac agtaacctaa
    28261 gttttgcatt ctttcgtaat taaatgcacc ttgaagaaca aatgaacgcc aaaacatact
    28321 tcttaattct ttttttgtta atttattcaa agtcaatctc tccttccgtt aaagtattga
    28381 ttgctaattg aggattttga ttattttctt tgttattgat ataaaagttt agtacaaatg
    28441 ctacacatac tccaaataaa gctatagcag ttatatctaa tccaccataa gatgctaaca
    28501 aaaaccctat aaagaaaaat acagacatct tttttgaaag taacatatcc ataagcaatg
    28561 caaaacctac tgctggcaac aatgttcctg caacacccag tccgtctaat ataactttag
    28621 gtattgcatt tatcaatgct gtaactttat cagcaccaat cataattgct aaaaaggttg
    28681 gaactgatgt acttaaaaag aataatatta ctggcaacca catcattatg gtaactttct
    28741 taaaatcagc ttgtttagca tagaaaactg ccttttgaga aaagtacgaa tttattattc
    28801 taactaatac tccaagagat tgtgctaaga ctgctactgg tactgctact gctaaagcaa
    28861 cttctgcacc attacctgat aatatagcaa aagctgtacc taatacgcct cctgttacta
    28921 catctggagg agtagctgca cctattcctg caattcccat ccaaattaat tcaagctgtg
    28981 caccaatcat aattcctgat tttatgtctc ctaaaactaa tcctactaac atacctgtaa
    29041 ctattggcct atcaagcata gattgaccaa atatacgccc atctagtata ccaactcctg
    29101 ctataatagc taacatagta gcttgtacta acatattgaa cctccatttt aacttagttt
    29161 aatttacatt aaattacatt acatttttga ttttgttttg attttctaat aactcattta
    29221 cataaacaat tccatttttt gcttcctcta atcctgattt aactattagt tttgtatcct
    29281 cctcaactaa taaaagtata gataaaagca ttggtaaatt tactcctgtc aataattcaa
    29341 atttgaaccc ttgtaaaagt aagtttgtac atatgtttgc cacacttcca ccaaaaacat
    29401 ctgttaagac aacaaattct tcactatctt tattatttga taatatactt ctaatttctt
    29461 tctcagcatc atctgctgat ttatccgttg tcatacaaaa atactcaata ttagttaatg
    29521 aaccaattat taatttactt gtgtcaacaa gctctctgga caattctcca tgtgttgcaa
    29581 ttagaaattt tttcattctc tttctcctaa attattttat taaatctgat agttgtttct
    29641 ttttgtctct aggtaacatt ctaaattcta tatcaatccc taaatcacct atttgtttaa
    29701 agttatttat atcatcatca tcaacagcaa ctaaatctgt aagtttcttc ttcccttcct
    29761 catatcttaa tcctcctaca tttatttctt ttaatactcc tcctgaattt ttagctacaa
    29821 ctaaagcatc tttggtattt tttactaaca ctaatacatt gcttttcttt gaagaagcaa
    29881 atttttctac tatttctcca gattcctcta ccccccttat atataaagtt acattgctag
    29941 gtttcgctaa gttcagtgac atagctttca tttggtcatt ttttgcttca tcatttgcaa
    30001 ctagtattac atttatacct agtgatgttg cccatccata tgcaacctga ccatgtatca
    30061 atctgtcatc aattctcatc aaagatacca ttttccccaa atcctccatc atacattaaa
    30121 atttttattg tttatactct catttatcta taaaagcaaa aagtatgcca aatactggca
    30181 tactttttta aatttcattc acttattttg taatcttgta ttttactgtg gtagaccata
    30241 gataatatta taaatatatc ctatctctga aattggtatt tgcacactat aactcttttc
    30301 tagcacacta aatgcatttt ttattagttt tacttcacta tgatggtttt tgattaacaa
    30361 atccatatca gtatactctt caatttcagt ttgtctaact aatctttcaa tcatacaact
    30421 taagtgaaca tataaagaaa tctttttatc atttgaaagt tttttctttt gaatattttc
    30481 tatagcatta attccttctt ctattctctc tattatcttt tttgaatcta aaatagttag
    30541 actatctatt actctaatta atgaaaaatt ctttacaata gaatcattta tgttctttat
    30601 tttttcattt tctactactc tgctaaatat tctaaaaaca tcatcttctc cttttcctga
    30661 tattatatcc tctaataata taaaatctac cccattcaca tttggattgg cagttcctac
    30721 tatagccatc acatcataca tttcaaaaac tggttcttta tctcccatag aaacaagact
    30781 atcataatca taaggtatta ttttgacatc aactattcca attaaacttt cggaaagtag
    30841 atgttggatt tttatagcag tacctatccc tgtaaaacaa gatgatatta tagcatattc
    30901 tttatttttt tgaggataat acaattgtat attaggttta gtttcttcat ccataatttc
    30961 tgcaatctct tcaatgtttt taccttgcat taataaattt cctacttcta gtgcagaaat
    31021 agtggatatt tggtctataa ataacattgg gctatttatc ttattcttta aatcttcaaa
    31081 tataagatta agagagccca tatcaaataa cacaattaaa ccattcttta tcctatctcc
    31141 ctctaggtat ctagacattt gttttgatac atcagcaata gtagcatcta taggcatatc
    31201 aatagctgta aatatatttt tacccaacat ccgattacat acattcgcca tactactggc
    31261 agtagcatat ccatgtgcta taatagtcgc attaacttga ttaaatttca ttcttataat
    31321 tgttgattta ataaatataa tcattatgat tgtatctaca ttattaagat acatatccaa
    31381 tctattcgtt attaatgttg atattttact tattatagag tattctttgt aactctcttt
    31441 ttttaaatat attagtaatt tattttctaa agctttatac tcatcagaca attgataaga
    31501 ttcgtccttc aaataaagat aagacgaaaa tgccaataca ttattcccat catattttat
    31561 attgttatta acttctaaat ttctaaatat atcctgcatt atcgatatta taagctccat
    31621 aagtacgtta ttattttcat cattatttga aaagactaaa ttgtccatta gtctaatcat
    31681 tagattagaa ctctttttac taaatttttc ctttgttatt tcattttttt ctagtctatc
    31741 aaagtaatct aaacatttta tgaaactttg atagattata tttcttttat ttcttccatt
    31801 tgacatttca atactaaatt gtttaggaga aaagataatg cttttgcttt taccactttg
    31861 gaattgaaat atatctacat tttctatata aagatttcta ggaaggtctt gaagagtaac
    31921 aaaaatattt ccatttcttc tttgattttt tgcataagct cgtccacatg catattttat
    31981 tacattttta cattcaccta tattcccctt gaattttatc tttaaaatcg catttaatgt
    32041 aatttgagtt atctctatag gcaaaccaag taccttactt tcttcataaa taaaatgttc
    32101 tacaatcttt cttttttcaa tagtccctct ttcttctata ttgggaacat aaatatttat
    32161 gggtattctt cttaaaaagg tttgtaaaaa ttcagataga ctttctgttg tagcaaatat
    32221 taatcttacc ctagcttttc taattactcc attctctcca atcctagaaa acgtacctgt
    32281 atccataaat gtaaataact tttcctgacc ttcactattt aatctatgta cttcatctaa
    32341 aaataaaaca ccaccatctg attgttctat tagacctgct ctagattcat ttgctccagt
    32401 atatgctcct tttacatgcc caaataatag actagacaat aactccaaat tattataata
    32461 ctgcgcacag tttaacacat tgtatggaga atttttttct aatacattac tgcttacact
    32521 atatttgtat attatcttgg ctaaaaaagt ttttcctact ccactttcac ctgtcagcat
    32581 tattgtaagt ccgccatttg gataaagtac agcggttttt atttgttcga ttacttcttt
    32641 taagctattc tcatatccta tgatactatt aaacacagtc tcttgcttta ataatttaca
    32701 ctcattttta agttcatcta aattttcata aatacttttt tttgtaggtc ctactacatc
    32761 atttatttta tttttaggta aaaaaataac aggtctactg tttatcttta taagattatc
    32821 agattttact aaatcattta ataatctact tgattgagtt ctacttaaat taaacttttt
    32881 tactatatct tctgttatta tgccactttc ttttttaagt tcatcaaagt tgttaaataa
    32941 tacacattca tttacaaaac ttaaaatttc atccctcatg ttcaacctcc aatacaaata
    33001 tcaataatac tataatatta gtatatcatt tatatattta tgaaaaagat aattatattc
    33061 ctatcttgat tctcttttgt aaggttgtaa aatcaaactt tttataagta taaaatctag
    33121 attttttaac ataatctcaa ggttcttatc tttccatata tctgacatag aatttatata
    33181 agaatatatt tattgtattt attataataa aaagtaaaac attataggta ttttaaaact
    33241 tattagcgaa gaaaatattt gtaactttta ttaccttatg aatattattt caaatttaaa
    33301 aaggctataa ataaatttat ttttaaataa atctacttat aacctcacaa taatacttat
    33361 aaattttatt ttttcacaat gacatatctc aaatatagtt aaaaatatat ctatttaatt
    33421 attaatattt aagtaataaa ttctcactca atcattaaat tcctttttat agtaaattac
    33481 tcttatttta cttataccaa atacatttat gtatagatat aaataagcac taaaaaaaca
    33541 attcaagaaa ccatatagta aacttaatta catctgttat ttgctcatat ctttagactt
    33601 atctatacaa gcaacaatag attttataac tgctgctcta aagccttctt cttctaatac
    33661 cttaacagct tctatagtag ttcctgctgg agaacaaacc atatctttta attcacctgg
    33721 atgttttcca gtttcaagaa ccatcttagc tgaccccatt actgcttgag atgcaaattt
    33781 ataagcttgt tgtcttggca ttccagctaa tactgctgca tctgccatag cttctataaa
    33841 cataaataca tatgcaggag aagaaccact aatacctgta actgtatcca ttaaatattc
    33901 tgatactatt tctgcctcac caaaagattc aaacagagcc ttaatcatat ttaactcttc
    33961 atctgttaca ttactatttt tacaaagagc tgacattcct tcgccaacaa gggctggagt
    34021 attaggcatt actcttacta tttttttatc tgaacctata aaactttcca gactttctat
    34081 agttttacct gctgctatag atactattat tttatttgca tctattaatt ctttaagtgg
    34141 agttaaagcc ttttcgcata tattaggttt aagtgctact attaccacat cagaatttgt
    34201 aacagctacc tttgaatcag ttgtagtatt tactccaaat tcttctttta ctttatctaa
    34261 ggcaacttgg cttaaatctg atacagttat atcttctgcc tttactaatt ctgactgtac
    34321 tatgccacct atcattgcac ttcccatatt ccctgaacca ataaatccta aagttttcat
    34381 atcaaatctc cttttttcta ttagttttat tttaaagtag ctaaattgac tttattttaa
    34441 ctgcttaaaa ttatcttatt tttataaaat ataaccttat tataactata ataaattatt
    34501 cttttgtatg tattacttac taatatgtgt atgatttact aaatataaat ttaacgattt
    34561 tttcattaaa cttaacgagc taacttccta tttagaaagt tagctcataa ttaatctaaa
    34621 attttaaaaa tggaatcaaa ccatttatac tttattatat cagttacgat tttatatagt
    34681 aagaagtttt atttacaagc aaacctagaa tgtttgctca gttcttccta ttatctcatc
    34741 ttgtagtgtt ctacttaaat tattgaaatg gtcactatat cctgcaactc taactattaa
    34801 gtctttataa tcctgaggat tcttttgagc ctctaacagt acatttttat caaatacatt
    34861 aaattgtata tgatgaccat ccatattaaa gtatgctctt actagattag ccatattatc
    34921 taaccctttt tctccttgaa ctactgatgg tgcaaatctt tgatttaata atgttccacc
    34981 agtttttatg tggtccatct tagcacaaga ttttataact gctgtaggtc cattagtatc
    35041 tccacctttt tcaggtgaaa ttccctctga aactggtttt gcacaaagtc taccatttgg
    35101 acttgctccc ataatttctc caaagtatat atgacaagtt gttggtaaca tatctactct
    35161 gtattctcca ccacaaacag ttggtctacc agttacctca ttgtaatatg cattgaatat
    35221 ctcttgcatt atttcatcag cataatcatc atcatttcca tatttaggag tcttatttga
    35281 aactaaatta agtatagctt catatccttc aaaattagca tcaagtgctt taagcaatgt
    35341 atccatatcg aattttttct tatcaaatac attatatttt attgctgtta aactatctgt
    35401 tatagttcct ataccaacac cttgtatata tctagtgttg tatcttgctc cacctctttg
    35461 gtaatccttg cctttttcta tacaatcatc aactattgta gacataagtg gacaaggcat
    35521 gtgttttgca catatatttt ctatcacagc atttccttct atttttatgt caatcatata
    35581 atgtaattgc tttttaaatg cttcaaatag ttcctcataa gattggaaat ttctagggtc
    35641 tccagtttca atacctattt gttttttact aattgggtca tatccattat ttaatgttaa
    35701 ttcaagtatt tttggaatgt tcatatatcc agttagaaca tatgcttctt taccaaaaca
    35761 tccagtttca acacaaccac tggttccacc aagtcttgca tcttctatag tttttccagc
    35821 ttccataagc tcttgaacta ttgcttcagt attataaaat gctggttgac cccatccttt
    35881 tcttgatatt tcacaagctc tctttaagaa tttttgagga gtctttttac ttatttgaac
    35941 atttgaacta ggttgtatca atttcatttc atccataaca tcaagtatta tataactaac
    36001 ttcattaaca ccatcttgac catctggatt tattccacca gtgtttatat ttgcaaaatc
    36061 tgtatatgtg ctactttctt ttaatgttat accaactttt ggtggtgctg gctgattgtt
    36121 aaatttaacc cataaacatt caagtaattc ttgtgctcta tctctatcta gtattccatt
    36181 ttctacatct ctttcataga aaggatttag atgttggtca agtcttcctg gagtaaaagc
    36241 atcccatata ttaagttcag tagtaacccc tatatgaaca aaccaataca tttgtatagc
    36301 ttgatgataa gtttctggtt tgtgagctgg tacaacatca caagtttcag caattagtaa
    36361 taaatctttt ttcttagctt catctgtttc ttcttctgcc atttgtcttg ctttctcagc
    36421 atatctttta cctaatataa ccattgcatc acaagctatt gccatagctt ctaaatctgc
    36481 ttttttatta tatgcatcta aatcattaag aaaatctagc tcttttaatc ttgcttctat
    36541 gtctttcttt aaatctaaaa atcctttttt atatattgta tctccacaaa ctgtatgtcc
    36601 tggggctctt tgttccataa actctgtaaa catacctgct tcatatgctg ctaaccactc
    36661 aggtgtcatt gcatttatta tcttatctct tgtttgtctc tttttccaaa aaggaattat
    36721 ttcttcttta tgtatttttc tagcttcttc tgatacgcta aaatttatta tatctctatt
    36781 gtgcattact tctaaatctt ccattgtatg acaacaaatt tctggatatg ttggtgctcc
    36841 attaggagaa tcaccttttt cacctactat taattctcca tcatttatgc taagagttct
    36901 attctcaata taatgcttaa atgataaagc acgaagtaca ggaatctcta cacttccctc
    36961 atatttttta taagcttctg tcataagtac tgctctttca atagatatgt gtggttctgc
    37021 attaatactt tcttctctta attttttagt tctctcaaaa gttcctcttg ccattttatt
    37081 accctccaat cttagtattg aaattacttg cttcaaacag tctttttatt tcctctaatt
    37141 tttcttctga tggtctttgt agttcttctc cttcatactt tttataaatt ttatcatact
    37201 tgtgtttacc aatattatga tatggaagaa gacttactgc ttgtatattc aaaggcttta
    37261 aaaactctat cattttttta acctctaaat tttcatcatc tacatttact cctacaatta
    37321 atggtattct tatatttatg ttagccccta attcacttaa aatcttaaca tttttcagta
    37381 ttaagtcatt tgattttcct gtaaatttta tgtgcttatc ttcatcaata agcttaatat
    37441 catataaaaa caaatctgca catttagcaa ctctttcata attttctgac tttgcatagc
    37501 cacatgtatc aattgctaca tggattccct ttgatttgca catgtttatt actccacaaa
    37561 tgaagtccat atcttgagcc attacttctc cacctgatag agttactcca ccacctgatt
    37621 cttcatagaa aattctatcc ttctctatct ctttaaccaa atctcttaca gaatactctt
    37681 gaccaacaat ctctcttgca ttgtttacac aatagtctaa gcaagtttca caaaactcac
    37741 acttatcttg gtctaagcat atttttgttt cacctttgta aattgcctta tgagggcata
    37801 tatttataca tgcttcacat tttgaacatc tttcttcatt atacaaaact tgttttgtat
    37861 atgtttgact ctctggatta tgacaccaaa cacattcaag tggacaccct ttaaaaaata
    37921 ctgtacttct tatccctggt ccatcatgta tgctacattt ttgtaagttt ataactaatg
    37981 gattcatgat ttttcacccc taaataatat ccattccatt ttttcatttt tatgcaattc
    38041 atcttcatag aatataccta tgaaaagcat ttctacaatt acataatact atatttgt
//
LOCUS       DAMKNB010000033        36095 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.035, whole genome shotgun sequence.
ACCESSION   DAMKNB010000033 DAMKNB010000000
VERSION     DAMKNB010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 36095)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36095)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36095
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.035"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            877..1107
                     /locus_tag="PC494_001863"
     CDS             877..1107
                     /locus_tag="PC494_001863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HDF3912365.1"
                     /translation="MSNKKKKYANILANECVACGSCIKACPRSAISVPCGISAKINRD
                     LCVGCGICEKICPASVIEIITILKEEEGKCHE"
     gene            1100..1681
                     /locus_tag="PC494_001864"
     CDS             1100..1681
                     /locus_tag="PC494_001864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HDF3912366.1"
                     /translation="MNNKKHWYDYLWIFSSIYLILGFVNIIFAWIGLICFFVPLAISI
                     VKGNKAYCNKYCGRGQLFNLLGNKLKLSRNRDIPKFIRSKWFRYGFLTFFMVMFANML
                     FSTYLVFEGSRNFKEVVTLLWTIKMPWQWAYHGTLVSPWVVQFAFGFYSVMLTSTVLG
                     LITMILFKPRSWCVYCPMGTMTQMICKAKSKSV"
     gene            complement(2259..2936)
                     /locus_tag="PC494_001865"
     CDS             complement(2259..2936)
                     /locus_tag="PC494_001865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HDF3912367.1"
                     /translation="MISQNEIDILTHSLPFWDKLTDLQKELLISSANTSHYKKGNPVH
                     CGDSDCIGILIIKSGTVRTYILSDEGREVTLFRLDDGDVCILSASCILKTITFDVYVD
                     AETDCDIIQISSSVFAKLSTENIHAELFSYKLATERFSDVMWAMQQILFMSFDKRLAS
                     FLIDEIAKNGSNTINMTHEQIAKYMGSAREVVSRMLKYFAREGIVSLSRGGIKVLDKD
                     KLRSLTL"
     gene            complement(3125..4489)
                     /locus_tag="PC494_001866"
     CDS             complement(3125..4489)
                     /locus_tag="PC494_001866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HDF3912368.1"
                     /translation="MKESDKRIELLGSAPISKALLSMGLPTMIGMMITALYNLVDAYF
                     VGGLGTSQMGAISVAFPLGQLVVGLGLLFGNGAASYIARLLGHGDNEKAGKVVSTSIY
                     SSIIVGTLVIIVIMIFLNPILKLLGATKSIMPYAISYASIYVVSSIFNIFNVTMTNIV
                     TSEGAAKTTMCAMLLGALLNMILDPIFIYTFGLGVRGASIATAISQIASTLVYVGYIL
                     SKKSIFSFRINECCFSKEIFSEILKIGIPTLIFQLLTSLAITLTNMEATKYGDSVIAG
                     MGAVTRITSLGSLVVFGFIKGFQPIAGYNFGSKNYDRLHIAIKTSILWTTVFCVVLGL
                     ILILFPKSIISQFTSGDILLIENGSKALRANGFSFMLFGFYTVYSTLFLALGKAKECG
                     FLGMCRQGVCFIPIILIIPVFYGLNGILYAQPIADLMAAIIAGFMSIRLHKELNLLKI
                     NGMH"
     gene            4617..5138
                     /locus_tag="PC494_001867"
     CDS             4617..5138
                     /locus_tag="PC494_001867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HDF3912369.1"
                     /translation="MATIDLIVLGIVKQQPKSAYDIQKAVEYRNISRWVKISTPSIYK
                     KVIQLEQKGYIESKTVKNGKMPEKAVYSLTELGETHFLDLMFDTSSKPINILLDFNAV
                     IVNLNSLTPEKQKLCLNNIEENVQELKKTIEENISIKTEVPETAKAVLEQQLVLAQAL
                     ETWINSLKDNMGN"
     gene            5595..6674
                     /locus_tag="PC494_001868"
     CDS             5595..6674
                     /locus_tag="PC494_001868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HDF3912370.1"
                     /translation="MPELLKNMYNRESLYEVAVAIQSVYNSFKVDEFIKSTMDETWNN
                     LELKARCRKISMSLGMYLPEDYKEALSILEKSVTGFYFAFFFPDFVEVYGQDDINWDL
                     SISALERNTEYWSSEFAVRAFIIKDEERMMAQMRKWSKHKSEHVRRLASEGCRPQLPW
                     GQAISKFKKDPTPVLPILEQLKTDTSTYVQKSVANNLNDISKTHPDLVISIAKDWYGK
                     NKSTNWIVKHGCRTLLKKGNRDVLALFGYDDTTSINIQDFTLETTSISIGEDLTFSFN
                     ILAKKATKTRLEYGIDYIKSNGKKSRKIFKISEVSLKENEKKSYMKKHSFADVSVRKH
                     YPGIHSIAIIINGIEKDKLDFELGI"
     gene            6998..7366
                     /locus_tag="PC494_001869"
     CDS             6998..7366
                     /locus_tag="PC494_001869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="HDF3912371.1"
                     /translation="MDVYSFWNDTLAQDAVKIRKYFHENAYINWHDTNEHFTLEEFII
                     ANCEYPDKWNGKVERVLEFGNLVITVTHVYAINKPLSFHVVSFISLKDDKIISIDEYW
                     GEDDDVPQWRLDKHIGKPIK"
     gene            7483..8286
                     /locus_tag="PC494_001870"
     CDS             7483..8286
                     /locus_tag="PC494_001870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDF3912372.1"
                     /translation="MEEKYILSDRGKVYYWIKESNSVFAKNLIFLPGLTANHHLFDFQ
                     IQYFSKNHNVLVWDAPAHGKSRPYLDFSYSNLVEELKVILDKQNMKKVVLIGQSAGGF
                     VAQSFIVKYPNMVEGLMMIGTCPYGTDYYSKSDIFWLKQTEWMLKLFPDKFLRNIISK
                     MCGATSEGRRSMLKMLEGYEKKELCHLMYLGFAGFIPEIQDLNIHCPVCLVVGDKDKT
                     GKVRKYNEQWHNKTGYPLHIIKNASHNVNVDKPNELNQIMDIFIKQLNI"
     gene            8671..9561
                     /locus_tag="PC494_001871"
     CDS             8671..9561
                     /locus_tag="PC494_001871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HDF3912373.1"
                     /translation="MIESIPAKQILQKVKFDNTRWFGIDYNMNLYRGCSHGCIYCDSR
                     STIYNIENFDKVRYKENVIEILSKELRSKRKKGVVGIGAMSDTYNPFEKQLCITKQAL
                     DLISENHFGVSIDTKSSLVVRDIPILQKIKKNNSAIVKLTITTANDELSKKIEPYVNP
                     SSVRFEAVKELNDSGIFCGILLTPMLPFLTDTKDEIRAIVEKAHKANAKFIYCMYGVT
                     MRSGQREFFYEHLRDISPKLVLKYQKTYGLNYVCTVQNKDSCEKLLREECARYGILTD
                     MKEIIKAYKRSESYTQIKFF"
     gene            10274..10717
                     /locus_tag="PC494_001872"
     CDS             10274..10717
                     /locus_tag="PC494_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDF3912374.1"
                     /translation="MIEIKTIEINKKSQIDLLMLADPCEEMIDKYLNKGTMYALYDNK
                     ELTCIAVVNEISKEICELKNIATYEHFQNMGYASKMIYHLLDVYSKKYSSMVVGTSES
                     GVPFYEKFGFVYSHKIKNFFVDNYPEPIFEGELQCVDMLYLSYNF"
     gene            10875..11045
                     /locus_tag="PC494_001873"
     CDS             10875..11045
                     /locus_tag="PC494_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3912375.1"
                     /translation="MDSNNNTIKSTVKKGISFGSCLAMIISYTAWKSIPWAIFHGLMS
                     WIYVLYYWVKYA"
     gene            11418..12515
                     /locus_tag="PC494_001874"
     CDS             11418..12515
                     /locus_tag="PC494_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rpn family recombination-promoting
                     nuclease/putative transposase"
                     /protein_id="HDF3912376.1"
                     /translation="MKEKLEEKSKIIKTSKEYKRTIIEEKDREWTKKLNDILSRGDFS
                     NEKLDKIKDLIPKEILTSENVGEVVTEDGYAKPEYDEVFKSLFTLNNDYDLLANFIND
                     ILKDAPYANRNIKQFTQIKRIIKVETDPTINYIGEKRPRLDILAEDEERNHINIEMQR
                     ALEEDYLERAEYYLSRVHGRKLEEGKEYKEIGKTVGIHILNHVKYNHIEDYVNCLRLT
                     MDGHPDIFSSKTALYFIELPKIRKSSCIANRVLIWGKLIDNPSHIDIRILSKTDYVIK
                     RALDRLKELGSNEDYLLNLKRGAYIMNKSRNFKEEIFQEGIEKGIAKGKREEKFNIII
                     KLKNKGYNLSEICDIIDDLNKSEVEKVYNQN"
     gene            12720..13208
                     /locus_tag="PC494_001875"
     CDS             12720..13208
                     /locus_tag="PC494_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3841 domain-containing protein"
                     /protein_id="HDF3912377.1"
                     /translation="MKFYTIQTLEFWNNNKNNKYLSNDYSFILEDFDIPYKWMYSQMT
                     NRIYEFDDSMIWVWTKRPDLRCSGYLEKGKKGVLLEIEISEDNVLLSEFDLWHLPLMD
                     ITVELYEDEQIEKKVSWERIFDLELCSKLNEVNIEDLTLQGVTSKVPLSNVKLIKEFV
                     AK"
     gene            13294..13701
                     /locus_tag="PC494_001876"
     CDS             13294..13701
                     /locus_tag="PC494_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3912378.1"
                     /translation="MSKQQTGIKSTLISEILGISYCIGATLVNKYFFKGSSIEYLPII
                     IWVLAMGAQWVYNKKYDDLIDEASKCILSRVNDIAIKVLFFSVAIVSIFLVTLDINVS
                     NLNIGMSLLVILFIQSLLKLILFIYFDRKGIYN"
     gene            13702..13920
                     /locus_tag="PC494_001877"
     CDS             13702..13920
                     /locus_tag="PC494_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF3912379.1"
                     /translation="MSVLLKTKIKSYREKNLMTQGELAKSVGVRRETIVHLENGRYNP
                     SLKLAMDIAKVFDTTVEELFEFIEENNI"
     gene            14135..14296
                     /locus_tag="PC494_001878"
     CDS             14135..14296
                     /locus_tag="PC494_001878"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3912380.1"
                     /translation="MKNQANGLKNELIIGKNQAYRLENELIIGKNQAYRLENELIIGK
                     NQAYRLKNK"
     gene            14689..14994
                     /locus_tag="PC494_001879"
     CDS             14689..14994
                     /locus_tag="PC494_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3912381.1"
                     /translation="MPSMIMEVVGVLFIAIGLILTFIEIKGNFPSFYGFGQNSIGKNA
                     VGIIAAGIALIFFRNGIDSIDSIATYGVFLAIELVVIVAYFLIRKKFTKEDKHLRTN"
     gene            15402..16091
                     /locus_tag="PC494_001880"
     CDS             15402..16091
                     /locus_tag="PC494_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF3912382.1"
                     /translation="MDILLVEDDKNIREMVYDFLISENYSVKTAIDGNTAIEIFKNYS
                     FDIILLDLMLPKSSGFEVLKYIRSVSVVPVIITTAKDSDTDKMLGLNLGADDYITKPF
                     SIVELLARIKANIRRATVYSSSRNSQDMVIQYKDLIINISKYVVSKNGIDLNLTHTEF
                     EIVKLLATNQGCAFSKEQLYNAIWKEPYYGNENVLNTHINRLRNKLSDGIEKNNYIKT
                     LWGIGYKMEEE"
     gene            16091..17008
                     /locus_tag="PC494_001881"
     CDS             16091..17008
                     /locus_tag="PC494_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF3912383.1"
                     /translation="MELFLVVISIVLFALYLKERNKSKKMESDYKCINSRLRDITNDD
                     EINYILVPSDISIVKETAVDINKLLEKFYSRQINYNRSEKAILQIFTNISHDLRTPIT
                     VLKGYIEMLYLQSQKEELSSSMRATVEKMQTNSNELVNSINNLFNMAKIQSGDMILNL
                     QKSNLTQLCHEIILEFYDLLDKENFNVEVNIEDRPIYANVDTEALQRILKNLIDNAIK
                     YGSDGRFLGISLYEKEKHVFIDIEDKGSGISETEKEHIFTRAYTADRKKGNGLGLAIS
                     QGLANSMGGSIYVNSRPNVKTVFTVKLKS"
     gene            17081..18007
                     /locus_tag="PC494_001882"
     CDS             17081..18007
                     /locus_tag="PC494_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF3912384.1"
                     /translation="MNYIIETHQLKKIYKDKAVVNAVNIHVKKGEIYGFVGPNGAGKS
                     TVMKMLLNLVKPNSGEIVMFSKKVEETDFEILKKIGTIIENPYLYENLTAKQNLDLHC
                     EYMGYYNKEHISEVLECVGLSKQSNKKVSKYSLGMKQRLAIARAILTKPELLILDEPI
                     NALDPEGIREMRELFRKLNTDYGITIFISSHILSEVEQIADTIGIIQDGKLIKEISMS
                     DIHKYQTDYVEVDVDNVELAGYLLEKEFGIKDFKITSESCIEIYDLRKDVKEISKIFI
                     QNQIGINSIGRKQSSLEDYFFQTTGTGGKETL"
     gene            18004..18684
                     /locus_tag="PC494_001883"
     CDS             18004..18684
                     /locus_tag="PC494_001883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF3912385.1"
                     /translation="MIHLMKLELKKVGLKRYFLFSMLGIFLCMFFVFTGLNDKSTSIY
                     DYDVTFRTISLFFCFYYIILFAVLNVAYIINEYTNKTILILFSYPLDRKKLILSKLLL
                     ITTLMISSMIVGYICCFTFVVVLDKYFNLVIGDFHISILSYWIPGAIKSIIIFCSLGI
                     WTFVVGMIRKSIPVTLVSSIIFINLRQFILAGTNTTQDSLISVFIIVGITVIGIYYIL
                     NHKVTEID"
     gene            18782..19117
                     /locus_tag="PC494_001884"
                     /pseudo
     CDS             18782..19117
                     /locus_tag="PC494_001884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427885.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Fic family protein"
     gene            20101..20751
                     /locus_tag="PC494_001885"
     CDS             20101..20751
                     /locus_tag="PC494_001885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDF3912386.1"
                     /translation="MKVKSNLDEILYHKIIESLIRGEYSVGQKILLNDLCEKFEVSRT
                     PVVQAVKMLNKDGVLTIMTNGKVYVPEYEYDMVKQVCETRTLIETYALEKMMQEEEEV
                     FQQKLDVIKRYSDKCEEYYRQEKSVELALADLELHKAIVEGANNEILNDVYVGIQGRF
                     IVVNYLIRPLKNRNYEGTVQDHFEILKFIEDRDTKKAVDKLRNHIQGTIKRFCEDE"
     gene            21100..23166
                     /locus_tag="PC494_001886"
     CDS             21100..23166
                     /locus_tag="PC494_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S9 family peptidase"
                     /protein_id="HDF3912387.1"
                     /translation="MKEVVGSLKKITKERTENTMKKLFTSETFLEYQFISDCQISPDG
                     GYTAFIVKKADIKENGYTSQVYILNNKTGELKQITSINSVGAYAWEDENTILFPALRN
                     EKVKEAVKNGKQCMSYYALSLNGGEAEELFRLPIKGGKLNPIGKGLYAVIDSYDNDRP
                     IVEGLPEEEQQKKINAYNKRHYEHFKEIPYAVNGEGYISRKRKRLYIYDSNINELKAI
                     TAPMFNVVGMKISDGKILYIGQEFKDVKGLKNGVYVFDTNTNTNVCILEKDKYIIKGF
                     ELYQNQVILNLTDALSYGNGENGDFYTIDIDTKEMKLLSGHQHHCIGNTVTSDVKMGA
                     GQTTKVDGEYIYYTSTVDMDCIIERIHIPTGKQEKVTQTGSVDFIDVKDGNIVCVGCL
                     GNGLPEVYTVENGTLCKKTHLNDHILEEYKISVPEYIESKGSSKWEIQGYVYKPVDYE
                     VGKKYPAVLAIHGGPRLTYGPYFMHEIQVFTSAGYFVFFCNPRGSEGRGNAFADIRKQ
                     FGDIDYIDFMEFTDTVLEKYTDIDKTKLAVEGGSYGGFMTNWIIGHTNRFAVACAQRS
                     IANWSGMEGTTDIGYYFCKGQTGASHMENHELQWKQSPLAYADKCVTPTLFLHGEKDY
                     RCYMQEAFQMFSALKIHGCPTKLCLFEGENHELSRSGRPKQKLQRLVEMLDWFSVYIK
                     KDNIGQ"
     gene            23183..25138
                     /locus_tag="PC494_001887"
     CDS             23183..25138
                     /locus_tag="PC494_001887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S9 family peptidase"
                     /protein_id="HDF3912388.1"
                     /translation="MEKIKIESSDIFEYIFPHDISCSPDGKHIAYIISNINEEKDCYE
                     HDLYVMDIKTEKQIHMTQTKDVTSFSWISNTELLFTSKRNKPKSGTTDFYTISIEGGE
                     AKKAFSIPKACSVPVSLGNKLWLLTTKNPTDSKKSEPDRAVEGVDYWTFTDKPFIRDG
                     ENFSQRRRVTLELYQEGENITKAITPKFCEVAGVDVSSDKNRILYTGQIYEDCATPFS
                     GLWEYHIDSGETKELVPQGKYQISLAKYIGKDKVMLQASTLDRSITQNHDIFILDLST
                     NEINMIASPDGMYATLLDVDAVYGGGRSNKVIGDKFIGARICRTMTEFNEFDTKTGNI
                     RIITKVDAFTSFDIYDNTMYTVMLKDYELAEIYSIDMTTGTMKKMTAFSKPYLDTHKV
                     SLPEKLTFVAKNKEEVDGFVIPPIDAKEGEKYPAVLFIHGGPKWAYGYMFTHLKQCVT
                     SKGMYVIYCNPHGGDGYGEKFLEMVERWGYVDYEHLMEFVDTCIEKYPGIDADRLGVA
                     GGSYGGYMTNWIIGHTDRFKAAASQRGISNLITASLIIDFGDRIMKQTCGDKTPWNHE
                     EVLWNHSPIKYVKNVKTPTLFLHSDRDYRCFMGDTFQMFTALKQLGVDTEMYLFHGDT
                     HGLSRNGRPSNRIARANAIVDWFERYL"
     gene            25154..26344
                     /locus_tag="PC494_001888"
     CDS             25154..26344
                     /locus_tag="PC494_001888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HDF3912389.1"
                     /translation="MSDMLLWFSVVLVLFAIGDLIASKTKAKVSAVFVTLLLFLILFV
                     TKAIPADIIEKAGMTAAASWSVPMIMFSMGTMLNVKQFIDEWRTVLTAWLGIVAVIVC
                     VSLCIPLFGKSTVLTSIPVINGALPATTIMTQAALEKGLTLAAATATVVFAIQKFIGT
                     PIASRAALQEANRLLVEYHEAKSKGIDLANVDTDKKEAENTGTKVKQAFCEKYDKYYS
                     TNVCIFFIALFSYLGYELSEIIHVNYSIVCLVVGVIVTRIGIVPKDILEKGKIKGFIN
                     MVVFAAVIPSLAKVSLTDLISLFVPIVGMFAASIIGIFLMMKVLPGWKIIGSKPLAFG
                     VGFCQMLGFPTTYLISNEVCNAVGETEEERAYLMSKIMPKLVVGGMACMISIVVAGLM
                     VPML"
     gene            27493..27867
                     /locus_tag="PC494_001889"
     CDS             27493..27867
                     /locus_tag="PC494_001889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDF3912390.1"
                     /translation="MKVLISNTSDKPLYQQIKEQIKEAIFTEELKEGDAMPSIRNFAN
                     DLKVSILTIRRVYEELENEGFLTRQVGIGTFISTGNLEILRDSKRRIVEQKMADMIKD
                     AKALGITQIELQEMMDILYQED"
     gene            27869..28726
                     /locus_tag="PC494_001890"
     CDS             27869..28726
                     /locus_tag="PC494_001890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF3912391.1"
                     /translation="MENILEVYNLNKTYTDFSLSNISFALPEDCITGFIGVNGAGKTT
                     TIRSILDVVKRDSGKIKIFGKDFDGNEKELKNRIGVVFDDSYFYEELSMAEMKSIIAP
                     SYDNWCEEDYQQNMKRFNLNPKQKIDTLSKGMKMKFALALALSHKAEFLIMDEPTSGL
                     DPLIRSQILDILTEYMKKCGRGVFFSTHITSDLDKIADMIVMIDNGRIILEREKDTLL
                     DEHRKVKGDIQFLNDETKKLFLNLEITGYGFIGITSKINEVQKNMPDILIERPTIEDI
                     MLAYIERRE"
     gene            28729..29367
                     /locus_tag="PC494_001891"
     CDS             28729..29367
                     /locus_tag="PC494_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 transporter permease"
                     /protein_id="HDF3912392.1"
                     /translation="MLIHLVKKDILIVKKYVLLILFIAIGIPLFILWRLPPFAQILGF
                     VLSIIFSEFMLCQYLLLKESQYSKASVLLCSTPYPRRGLVQSKYVLFAMVFIYCTLVY
                     WIENLLIPQIGTFDLTYILIVLLISSIIYGVYMPIQYKLGYETTKFFFVVIIMASSFV
                     LPLTIAHSNFEIPFIYQYPSMIVNIVLFLLSLIILLASMFISIKIFSNKELV"
     gene            30373..31107
                     /locus_tag="PC494_001892"
     CDS             30373..31107
                     /locus_tag="PC494_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HDF3912393.1"
                     /translation="MNLAKGLDVLKISSNVFGEDKVMYIPVIYTEDDATLIDTGLPGQ
                     GDLIIDALNKSNTSFDRLKNIIITHHDIDHIGNINYLREKSKNNIKVYAYKSEISYIT
                     GEETPFKLYMLEQMVDKIDDKMLSMLNVMGLGFKSSYTKVDVSLDNHEKLNLGEEIEV
                     IHTGGHTRGHICLYLKESKVLIAGDLLQVENGELKPVDVMYSNKQELKDAIKNISNYD
                     IETIVFSHGGLYQRNIIGTLKNLIIE"
     gene            32683..33939
                     /locus_tag="PC494_001893"
     CDS             32683..33939
                     /locus_tag="PC494_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HDF3912394.1"
                     /translation="MIEKFKTLIWIKMIIKIKSVYKTYGGLFLLGLIGIPIGAIIGLI
                     DTIFGTVLLKVTDIRETYPMYLIPFLAVVGVVIAYCYFKFGGKSSKGMNLIFEVGHGE
                     EEIIPLRLVPFIILGTWLTHLFGGSAGREGVAVQIGATFSHWVGKRLPIKNASSIFLV
                     TGMAAGFAGLFETPIAAILFAMEVLVAGSLEYQSLFPAFTASFTASAVSKALGLEKFS
                     FALSSKVVFDLSIFWKLIVLGIIFGMVGGAFAWCLKLSKRKIGNRLKNPMIRIAIIGV
                     CLSVLFLLFYKGRYSGLGTNLIQNSFYGGEIYSFDWLLKFILTILTLSAGFQGGEVTP
                     LFSIGASLGVLLAGFFNLPIELVAALGYASVFGSATNTFFAPVFIGAEVFGYSYLPYF
                     FVVCAISYIFNMDKSIYSLQKISTKQ"
     gene            34002..35195
                     /locus_tag="PC494_001894"
     CDS             34002..35195
                     /locus_tag="PC494_001894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HDF3912395.1"
                     /translation="MLTSLALIFLLGMASGGIFKRIKLPNLLGMLLTGIILGPYVLNL
                     IDNSILDISSDLRKIALIIILTRAGLSLDINDLKKVGRPAVLMCFIPATFEIVGMIVL
                     APKLLGVSILEAAVMGAVVGAVSPAIIVPKMLKLMEEGYGTEKSIPQMLLAGTSIDDI
                     FVIVMFTVFTGLAQGNSISAISFLQIPVSIILGVIVGAVIGICLAVFFKKIHMRDSAK
                     GVLLLSISFLMISLETALEGIVPFSGLLAVMSIGIFLQIKYRVVARRLSIKYSKLWVG
                     AEILLFVLVGATVDISYAFKAGIGAVILIFGVLLFRMVGVFFCLIKTNLTIKERLFCM
                     IGYIPKATVQAAIGGVPLAMGMASGQLILTLAVLAILITAPLGAFGIDVTYKKLLTSV
                     KGENK"
     gene            35396..35776
                     /locus_tag="PC494_001895"
     CDS             35396..35776
                     /locus_tag="PC494_001895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HDF3912396.1"
                     /translation="MCLKKLSKLELVIMKFIWNLDIKTNSYEIIDYMKEEHNLPEKVA
                     LKTLSKLSKKRFLYVQETGKCMYYTVAIKEKAYLEFISRNVQNLLKNNFIRNLLVSFH
                     EEELTEEKIKSLENWVVNWEEAYV"
BASE COUNT        13798 a         3904 c         6151 g        12242 t
ORIGIN      
        1 atgattaata gagtaagagt gtaaatagag ataaacttca atatgggttt aacttgtgat
       61 taatagagta gggtgtaact aaagataaac ttcaatatga gtttaacttg tgattaatag
      121 agtaaggtgc aactaaagat aaacttcaat atgagcttaa cctatgatta atagagtaag
      181 aatgtaaata gagataaact tcaatatggg cttaacttgt ggttaataga gtaagagtgt
      241 aactaaagat aaacttcaat atgggtttaa cttgtggtta atagagtaag aatgtaaata
      301 gagataaact tcaatatgag cttaacttgt gattaataga gtaagagtgt aaatagagat
      361 aaacttcaat atgggattaa cttgtgatta atagagtaag agtgtaacta aagataaact
      421 tcaatatgag cttaacctat gattaataga gtaagaatgt aaatagagat aaacttcaat
      481 atgggtttaa cctgtggtta atagagtagg gtgtaactaa agataaactt caatatgagt
      541 ttaacttgtg gctaatagaa taagattgtg aataaagtta tagttttaga tgggtattaa
      601 cctgttacta atagaatatg attaggtgta aaattataga gctgtataag aaaatattat
      661 agatatatta aatattagat aataaatatt tatatagata cacaaaagaa aaggcgatat
      721 gaagctaaac ttaatgactt catatcgttt tttatttgaa actcctttgt atttagagtg
      781 tgatttttaa tattgaggtt ttatgtgatt aagtcacaga taaaaagtaa gtatcttgat
      841 ataattctta tagattaata atatagggag gttattatgt ctaataaaaa aaagaagtat
      901 gcaaatattt tagcaaatga gtgcgttgct tgtggtagct gtataaaagc atgtccaaga
      961 agtgctatct cagttccatg tggcattagt gcaaaaatta atagagattt atgtgttgga
     1021 tgtgggattt gtgaaaagat atgtccagca tctgtaattg agattataac aatattaaaa
     1081 gaggaagaag gtaagtgtca tgaataataa aaaacattgg tatgactatt tatggatttt
     1141 ttcttcaata tatttgatat tgggatttgt aaatattatt ttcgcttgga ttgggctaat
     1201 ttgtttcttt gttccactag ctatttctat tgttaaggga aataaagctt actgtaataa
     1261 gtattgtgga agagggcaac tgtttaattt gcttggaaat aaattgaagc tgtcaagaaa
     1321 tagagatatt cctaaattta ttagaagtaa gtggtttaga tatgggtttt tgacattttt
     1381 tatggtaatg tttgctaata tgcttttttc aacttattta gtgtttgaag gaagtagaaa
     1441 ttttaaagaa gtagtgactt tgttgtggac tataaaaatg ccttggcaat gggcgtatca
     1501 tggaacttta gtttcacctt gggtggtaca gtttgcattt ggtttttata gtgttatgct
     1561 tacatcaact gttcttggtt tgattactat gatattgttt aaacctcgtt catggtgtgt
     1621 ttattgccct atgggtacta tgactcagat gatatgtaag gcaaagagta agtctgtata
     1681 gaaaggcctt atgtgatatt tacagttttg ttcaagtaga gatgagtagt aggtttgaat
     1741 atatatgaca aatatatgag tataggggca tagatttagt ttgtgtaagg caaactgatt
     1801 tatgcttctt ttttatgtct tagattattg gctaagtaga aacaatgaat ttagatatta
     1861 agaattattc agttatttga agaaaataga ataataatta acattatatg aatggatatt
     1921 cattacatat aagcagttaa tagcaagatt tatttaatat gaaataggtc aagtatttaa
     1981 actaaataag gtcatgacaa ttaatataag tatagatata aaaagattag aagttataac
     2041 ttataaaagg tattctatat aagtagtatg tggaaaatag tcaaattaac ttattagaaa
     2101 caaaaaatat acataaaaaa taaatgtaaa tatcaaataa gatactatat aaaaatagat
     2161 ataagtatct tttttattat tgaaattatg aaaatatatt ttattttaca caaaaaagag
     2221 tgcctcatga actaaaaagt tcattttgag acacactttt acagtgtcaa agaacgaagt
     2281 ttatccttat ccaatacttt tataccacca cgagataaag acacaatacc ttctctagca
     2341 aaatatttca acattctcga tacaacttct ctggcactac ccatatactt agcaatttgt
     2401 tcatgagtca tatttatagt gttactgcca tttttagcta tctcatcaat taaaaaagat
     2461 gccaaacgct tatcaaaact cataaaaaga atttgttgca tagcccacat aacatcagaa
     2521 aaacgttcgg tagctaattt atatgaaaat aactctgcat gaatattttc tgtagataat
     2581 tttgcaaaaa cagaggaact aatctgtata atatcgcagt ccgtttcagc atctacatag
     2641 acatcaaaag ttattgtttt tagaatacag gaagctgata aaatacatac atctccatca
     2701 tcaagtcgga acagtgtaac ctctcgacct tcatctgaaa gtatgtatgt acgcactgtt
     2761 ccagatttta taatcaaaat accaatacag tcactatcac cacaatgtac tggattccct
     2821 tttttgtaat gcgaggtatt tgctgaagaa attaataatt ctttttgtaa gtcagtaagt
     2881 ttatcccaaa aaggcaagct atgtgtaagt atatcaattt cattttgtga aatcatacaa
     2941 tatctccttt cttaaattgt tataatccca tgatacaagt gaatagataa attgacaagt
     3001 agtttgttaa gaggattatt tagtcagata gtaatagtat gatttatgta gaaaaaatat
     3061 gataatatat attcttgcta ttaatgagaa agtaatatgt tttgatgata gtaggtttgt
     3121 ataactaatg cataccgttt atttttaaaa gattaagttc cttatgtaac cttatagaca
     3181 taaaaccagc aattatagca gccatcaaat cagctattgg ttgtgcatat aagataccat
     3241 ttaacccata gaatacagga ataatcaaaa ttatagggat aaaacagaca ccttgtctac
     3301 acatacctaa aaatccacat tcctttgctt ttcctagtgc gaggaataat gtagaataca
     3361 ctgtatagaa tccaaatagc ataaatgaaa acccatttgc cctaagagct ttactaccat
     3421 tttctattaa taaaatgtca ccacttgtaa attgtgaaat tatagatttt gggaagagta
     3481 tcaatataag accaagcact acacaaaata ctgtagtcca taatatggaa gtttttattg
     3541 ctatatgtaa tctatcgtag ttctttgaac caaaattata accagcaatt ggttggaaac
     3601 cttttataaa accaaataca acaagactac ctaaagatgt tattcgtgtt acagcaccca
     3661 ttccagctat cacagaatca ccatactttg tagcctccat attagttaat gtaatggcaa
     3721 gactagtcaa taattgaaat attaaggtag gtatgccaat ttttaggatt tctgaaaaaa
     3781 tttcttttga aaaacagcat tcgttaattc taaaactaaa tatacttttc ttgcttaaaa
     3841 tatatcctac ataaacaagt gttgaagcaa tctgtgagat agctgttgca atagaagcac
     3901 cccttacccc cagaccaaaa gtataaatga atatcgggtc taaaatcata ttaagcaaag
     3961 cacctaataa catagcacac atagttgttt tagcagctcc ttcacttgtg acaatattag
     4021 tcatagtgac attgaatata ttaaaaatag atgacacgac ataaatgcta gcataagata
     4081 ttgcgtaagg cataatactt tttgtagctc ctaacaattt taaaattgga ttgagaaaaa
     4141 tcataatcac aataataact aatgtaccca ctataatact actgtaaata gatgtactta
     4201 ccacttttcc tgctttttca ttatcaccat ggcctaaaag tctggcaata tatgaagcag
     4261 ctccatttcc aaacaataat cctaatccca caacaagctg acctaatgga aatgcaacgg
     4321 atatagctcc catttgactt gttccaagtc cacccacaaa gtatgcatca accaaattgt
     4381 ataatgcagt tatcatcata cctatcatgg taggtaatcc catagataac aatgcttttg
     4441 agattggggc agagcctaat aattcaattc ttttgtcact ttctttcata cttaacactc
     4501 ctcttctatt gacattaagt ctaaattata atactataaa ttatagtaag tatggaaaat
     4561 agtactataa tttatagtat ttgtcaatag taagaaaact aaaggagatg atttttatgg
     4621 ctacaataga tttaattgta ttgggaatag taaagcaaca acccaagagt gcttatgata
     4681 ttcaaaaggc agtggaatac aggaatatat cacgttgggt taaaataagt acaccatcaa
     4741 tttataaaaa agtaattcaa ttagaacaaa agggatatat tgaaagtaaa actgtgaaga
     4801 atggaaaaat gccagaaaaa gcagtttatt cattaactga attaggtgag acacattttt
     4861 tagatttaat gtttgataca tctagcaaac caataaatat tcttttagat tttaatgctg
     4921 ttatagtaaa tttaaatagc cttacaccag aaaaacagaa attatgtctc aataatattg
     4981 aagagaatgt tcaagagtta aagaaaacta ttgaggaaaa tataagtata aagacagaag
     5041 taccagagac agcaaaagca gtattggaac aacagttggt gctagcacaa gcattggaaa
     5101 cctggataaa ttctttaaaa gataatatgg gaaattagaa ttagagaagc taacttaata
     5161 atcattaaac aaaaaccagc atatttaata atgagatatt agaaaaaata aaacaaatga
     5221 tataaactga aaagtatatt taaaataaag ctcacttaat tgagggagaa tgttaaactt
     5281 tttaagagca agagcaagag caagagcaag agcaagagca agagcaagag caagagcaag
     5341 agcaagagca agagcaagag caatcagtaa agtataaaat tctattacta taataaaaga
     5401 tagaactaga agtctttatg aaagtgggaa aagtgtttat ataaataaat ttatatagtt
     5461 tatagtttaa cagtaggaaa tatcgtatga gtgagaatat cgtattttac ataaagattt
     5521 agcaatatga cacactgttg tcgtgttctg taggatatga ttaataaatc agatatgaaa
     5581 ggagagtgag taatatgcca gaattactaa aaaatatgta taatcgtgag tcactttatg
     5641 aagttgcagt agctatccaa tcagtttaca actcatttaa ggtagacgag ttcataaaat
     5701 ctacaatgga tgagacatgg aataacttag aattaaaagc cagatgtcga aagataagta
     5761 tgagtttagg aatgtattta ccagaagact ataaggaagc tctttccatt cttgaaaaat
     5821 cagttacagg tttttatttt gcttttttct ttccagattt tgttgaagtt tatggtcagg
     5881 acgacataaa ttgggattta tctataagtg cattagaaag aaatactgag tattggtctt
     5941 cagaatttgc tgtaagagca tttatcatca aggatgaaga gcgtatgatg gcacagatgc
     6001 gtaaatggtc taagcataag agcgaacatg tacgaagact tgcaagtgaa ggttgtcgtc
     6061 cccagttgcc ttggggacaa gcaatatcca aatttaaaaa agaccctaca cctgtactgc
     6121 ctatattgga gcaacttaaa acagatacat caacgtatgt acaaaagagt gttgctaata
     6181 atctaaatga tatctcaaaa acacatccag atttagtcat aagcattgca aaggattggt
     6241 atggtaaaaa taaatccact aactggattg taaagcatgg ttgtagaact ctgctaaaaa
     6301 aaggaaatcg tgatgtatta gctctttttg gatatgatga tactacttca ataaatattc
     6361 aggattttac tttagaaaca acgtctattt ctattggaga ggatttaact ttttcattta
     6421 atattttagc aaaaaaagcg acaaaaacaa ggctcgagta cggaattgat tatattaaat
     6481 ctaatggaaa aaagagtagg aagatattta aaatatcgga ggtttcatta aaagaaaatg
     6541 agaaaaagtc atatatgaaa aaacattcat ttgcagatgt aagtgtaagg aaacattatc
     6601 caggtataca ctcgattgct attattatta atggtataga aaaagataaa cttgattttg
     6661 aattaggtat ataattttac taacagaata atctatatca gatactttgc taaacttata
     6721 taatatattt tactaaattt atattaggta gtttactact tgtttactga atttaaatac
     6781 aaagaaatcc aggtgttaat ccctgccgat taaaggaata tgagcataac acaaaagtag
     6841 aacttatcaa ttctgttacg ggtatagtag taaatccata gaatcacaat tagaagatga
     6901 agtgtaaaaa ataagttagt gttgatttta gttgctagtg atattgaata gttatgcaat
     6961 acccatataa attagaattt gtagaggaga aatgtaaatg gatgtatata gtttttggaa
     7021 tgacactttg gcacaagatg ctgttaagat aagaaaatat tttcatgaaa atgcttatat
     7081 taattggcat gatacaaatg agcattttac tttagaagaa tttattattg caaattgtga
     7141 gtatcctgat aaatggaatg gtaaagtaga aagggtgcta gaatttggaa atttagtaat
     7201 tacagtgaca catgtttatg caataaataa accactatca tttcatgtcg tttcatttat
     7261 cagccttaaa gatgataaga ttatttctat tgatgaatat tggggagagg atgatgatgt
     7321 gccacagtgg agattagata aacatattgg aaagccaata aaatagtgtt tgttctgttt
     7381 tataactgaa attttgataa catttgatat tttgatttgt cattggtcaa catagtcgtt
     7441 agtgtaataa tttaaaaaag tagaatttgg agagtgaaca ctatggaaga aaaatacatc
     7501 ttatctgacc gagggaaagt atattattgg ataaaagaaa gtaatagtgt gtttgcaaag
     7561 aacttaattt ttttgccagg actaacagca aatcatcatc tttttgattt ccaaatacag
     7621 tacttttcaa aaaatcataa tgtattggta tgggacgctc ctgctcatgg aaaatcaaga
     7681 ccttacttag atttctcata ttctaacttg gtagaagaat tgaaagtaat tttagataaa
     7741 caaaatatga aaaaggttgt acttataggg caatcggcag ggggatttgt ggcacagtcc
     7801 tttattgtaa aatatccaaa tatggtagaa ggattaatga tgattggaac ttgtccatat
     7861 ggaactgact attatagtaa gtcagatatt ttctggttaa aacagactga atggatgtta
     7921 aagttattcc cagataaatt tttgcgaaac ataatatcta agatgtgtgg agctacgtct
     7981 gaaggcagaa ggagtatgct gaaaatgtta gaaggctacg aaaaaaaaga actgtgtcat
     8041 ctcatgtatc tgggatttgc tgggttcata ccagaaattc aagacttaaa tatacattgt
     8101 ccagtttgtt tggtggttgg agataaagac aagacgggta aagtgagaaa atataatgag
     8161 cagtggcaca ataagactgg gtatccattg cacattataa aaaatgcttc acataatgta
     8221 aatgtcgata aacctaatga actaaatcag attatggata tatttattaa gcaattaaat
     8281 atataaaaac tacatactca ttaggtaaat tatgtagtat atgtgtttac agatggttat
     8341 agaaataaat atgtaataaa ctacttaaca cttaaaaagt ggatttgtcc agagcataat
     8401 acaaagcatg atatataaat ttttaagcga aatacatcaa aagaagtatt agaattagtg
     8461 gagataaaac agctattaga gattataaat aaatagtttt aaaggtacta cgaatataga
     8521 ggaaggtaaa tcatacgtta ttcaaggatt ataaatgatt agtttaaaag tactatcgga
     8581 taggtctctg catatttaaa ccttagtaaa ggtagttaaa gtagtagttt aaaaactaaa
     8641 aaattatata aaggaattag gtataagaaa atgattgaga gtataccagc aaaacaaatt
     8701 ttacaaaaag tgaaatttga caatacaaga tggtttggaa ttgactataa tatgaatctc
     8761 tatcgtggtt gttctcatgg atgtatatat tgtgatagcc gtagcacaat atacaacata
     8821 gagaattttg acaaagttag atataaagaa aatgtgatag aaattttaag taaagaattg
     8881 cgttcaaaaa gaaaaaaagg tgtagtaggc attggagcta tgtctgacac atataatcct
     8941 tttgaaaagc aactttgtat tacaaagcaa gcactagatt tgatttcgga aaatcatttt
     9001 ggagtgtcta ttgatactaa aagtagtttg gtggttagag atataccgat tttgcagaaa
     9061 attaaaaaaa ataattctgc tattgtaaag ttgactataa ccactgcaaa tgatgaatta
     9121 tcaaagaaaa tagaacctta tgtaaatcca agttctgtac gatttgaggc agtgaaagaa
     9181 cttaatgatt ctggaatttt ttgtggtata ttattaactc ctatgcttcc atttttgact
     9241 gatactaaag atgaaatacg agcaattgta gaaaaagcac acaaggctaa tgcaaaattt
     9301 atttattgca tgtatggtgt aacaatgcgt agtggtcaga gagagttttt ttatgagcat
     9361 ttaagagata tatcaccaaa attggtactt aaatatcaga aaacatatgg tttaaactat
     9421 gtatgtactg tacaaaataa agattcttgt gagaagttgt taagagaaga atgtgcacgt
     9481 tatggtattt tgacggatat gaaagagatt ataaaagcgt acaagaggtc ggagtcatat
     9541 actcaaataa aattttttta agataggctt tggatgagat ataatagtgg tgattgatgt
     9601 gttgatatta tagttgattg ttagagagga tattatagat gaatattagt attgatattc
     9661 taggtaattg ctagagttag tattatagat gaatattaat attgatattc taggtaattg
     9721 ctagagttag tattatagat gaatattagt attgatattc taggtaattg ctagagctaa
     9781 tattatagat aaatattagt attgatattc taggtaattg ctagagctga tattatagat
     9841 gaatattagt attgatattc taggtaactg ctagagctaa tattatagat gaatattaat
     9901 attgatattc taggtaattg ctagagctga tattatagat gaatattaat attgatattc
     9961 taggtaattg ctagagttag tattatagat gaatattagt attgatattt taggtaattg
    10021 ctagagctga tattatagat gaatattaat attgatattc taggtaattg ctagagttag
    10081 tattatagat gaatattagt attgatattc taggtaattg ctagagctga tattataatt
    10141 tattattagt attaatattc tagggaatta tcactatatt ttaaaaagta aaaatatata
    10201 tcaaaatgaa ctaaataagt actgtaagaa gtttgttaaa ttaaggtttg aataaagtga
    10261 gggtggagaa cttatgatag aaataaaaac tatagaaata aataaaaaaa gtcaaattga
    10321 ccttttaatg ttagccgacc catgtgaaga aatgattgat aaatatctca ataaaggaac
    10381 tatgtacgca ttgtatgata ataaagaact tacttgtata gcagttgtaa atgaaatttc
    10441 caaagaaata tgtgaattaa aaaacattgc tacatatgag cattttcaaa atatgggtta
    10501 tgcctcaaag atgatttatc atcttttaga tgtttatagt aaaaaatatt catcaatggt
    10561 tgttggtaca tctgaaagcg gagttccttt ttatgagaag tttggatttg tttattcaca
    10621 taaaattaaa aacttttttg tagataatta tccagaacca atctttgaag gagaattaca
    10681 atgtgttgac atgttgtatc tatcatataa cttttagata ggttaatata attaattaat
    10741 tcatataatt atcggaatta taatttataa attatgtata ataagagtat aatttattta
    10801 gaagctgtta tattgtatta tattcaaata agatatataa taacttgttt attttgaatt
    10861 ttggaggatt aattatggat tcaaataata atactataaa atcaactgtt aaaaagggta
    10921 tttcttttgg ttcttgttta gcaatgatta tttcttatac tgcatggaaa tctattccat
    10981 gggctatttt tcatggctta atgagttgga tatatgtact ttattattgg gttaagtatg
    11041 catagattaa attaataaat aagtatgtaa tattgtaaag tttaagaaac aaaatgtaag
    11101 ggagtgtctc gaagtgaact tttagtttat aaggcactct tttttgtatt aaataaaata
    11161 tattttcatt atttaaacaa tgaaaaagat gagtatctct attttaatac atacccttat
    11221 attcattcat ttatcaacaa tagttttaaa aagaaagcta tctaaaatct attgtaatct
    11281 aagtgcttct ctttaaagtc ttaactttag taatgatata taagtttata aggttcttat
    11341 ttcaataatg caaattttac ttagaagttc agactttggt atgaagaaat gggtaataat
    11401 aaaaaagagg tgttgatatg aaagaaaaat tagaagaaaa atctaagatt attaaaacat
    11461 caaaagagta taaacgaact ataattgaag aaaaggacag agaatggacc aaaaaattaa
    11521 atgacatact tagtagaggt gatttttcta atgaaaaatt agataaaatc aaggatttaa
    11581 ttccaaaaga aatattgact agtgaaaatg ttggagaagt tgtaactgaa gatgggtatg
    11641 ctaagcctga gtatgatgag gtatttaaat cattgtttac tttaaataat gattacgatt
    11701 tacttgcaaa ttttataaat gatatcctca aagatgctcc atatgccaat aggaatatca
    11761 aacagttcac tcaaataaaa agaataatta aggttgaaac cgacccaaca attaattaca
    11821 ttggtgagaa aagacctaga cttgatattt tggctgaaga tgaagaacgt aaccatataa
    11881 atattgagat gcaaagagct cttgaagagg attatttgga aagagctgaa tattatctta
    11941 gtcgtgtaca tggtagaaag ttagaagaag gtaaagaata taaagaaatt ggaaaaactg
    12001 ttggaataca tatactaaat catgtaaaat ataatcacat agaagattat gtaaattgcc
    12061 tgagattaac aatggacggg catccagata ttttttctag taaaactgca ttatatttta
    12121 tagaacttcc aaaaattcgt aaatccagtt gtatagcaaa cagagttcta atatggggta
    12181 aacttattga taatccttct catatagata ttagaatact atctaaaacg gattatgtta
    12241 ttaaaagagc acttgataga ttaaaagaat taggtagtaa tgaggactat ttattaaatt
    12301 taaagagagg tgcgtatatt atgaataaaa gtagaaattt taaagaagaa atttttcaag
    12361 aaggtatcga aaaaggtatt gcaaaaggga aaagagaaga gaaatttaat atcatcataa
    12421 aattaaaaaa taaaggatac aatttgagtg aaatatgcga tattatagat gatttgaata
    12481 aatcagaggt tgaaaaagtc tataatcaaa actaatacta tgattgagat ggcactagat
    12541 aaatacaaag cttcctcttt taaatttaaa ttaatataaa actttgttat ttaaatatgg
    12601 tagatataaa gagatatata aataataggt acaaagaggt gtataaataa aggagataat
    12661 tcaaaataaa agtttgaacc atctccttct tatagaaaaa caaaggggtt gatttatata
    12721 tgaaatttta tactatacag actttagaat tttggaataa caataaaaac aataaatatc
    12781 tatcaaatga ttattctttt atattagaag actttgatat tccatacaaa tggatgtata
    12841 gtcaaatgac aaatagaata tatgaatttg atgatagtat gatatgggtt tggacgaaga
    12901 gacctgattt aagatgtagt ggttatttag aaaaaggaaa aaaaggtgtt ttacttgaaa
    12961 tagaaataag tgaagacaat gtgttattat cagaatttga tttatggcat ttacctttaa
    13021 tggatattac tgtagagctt tatgaagatg aacaaattga aaagaaggta agttgggaaa
    13081 gaatatttga cttagaactg tgttcaaaat taaatgaagt taatatagaa gatttgacat
    13141 tgcaaggagt gacatctaaa gtgcctctat ctaatgtaaa attaataaaa gaatttgttg
    13201 caaaataata tttttattga aatttattca aaaaagttat atatttataa caagaggtgt
    13261 tataaataca taacttttta agggggattt tatatgtcta aacaacaaac tggtattaaa
    13321 tcaacactta tttcagaaat attgggaatt tcttattgta ttggagctac attagtaaat
    13381 aagtattttt ttaaaggaag tagtattgaa tatcttccta taattatttg ggtattagct
    13441 atgggagctc agtgggtcta taataaaaag tatgatgatt taattgatga ggcatcaaaa
    13501 tgtatactat caagagttaa tgatattgca ataaaagtat tgtttttttc tgtagctata
    13561 gtatctatat ttcttgtaac tttggacata aatgtgtcaa atttaaatat aggaatgtct
    13621 ttattagtca ttttgtttat tcaatccttg ttgaagttaa ttctatttat atattttgac
    13681 agaaagggga tatacaatta ggtgtcagta ttactaaaga caaaaattaa atcctataga
    13741 gaaaagaacc ttatgacaca aggtgaactt gcaaagtcag taggagtaag acgtgaaact
    13801 attgtacatt tagaaaatgg tcgctacaat ccttctttaa aactggcaat ggatattgct
    13861 aaggtatttg atacaactgt agaagagtta tttgaattta ttgaagaaaa taatatttaa
    13921 atttcatgta ttacttatgc attagagaat gaattaatta taggtaaaaa accaagctta
    13981 tagattagag aataaatgac ttatagatga aaaaccaagc taatggatta aagaatgaat
    14041 gatttataga tgaaaaagaa agcttataga ttagagaata aatgatttat aggtaaaaac
    14101 caagcttata gattagagaa taaatgactt atagatgaaa aaccaagcta atggattaaa
    14161 gaatgaatta attataggta aaaaccaagc ttatagatta gagaatgaat taattatagg
    14221 taaaaaccaa gcttatagat tagagaatga attaattata ggtaaaaacc aagcttatag
    14281 attaaaaaat aaatgattta tagatgaaga actaaactca tagattaaaa aataaatgac
    14341 ttatagatga aaaatcaagc tcatagatta aagaataaat aacttattag atgaaaaaac
    14401 aagcttatag ataagaagtc catgcttata agccagaaaa tgaatacttt aatagattaa
    14461 aaaatacata tttgtgaatt atagaatgaa tgactccata aactagaaaa tttataataa
    14521 tatctatatg aaaattagaa ttattttatc acaaaaaaat taagttaaat aaatatgaaa
    14581 ttacttccaa atatacttcc aaaaacatgt aatcgcatat ataatataat tataaaaata
    14641 ataaatattt ttatagtagt agttaattat taataaggag gggtcaaaat gcctagcatg
    14701 attatggaag ttgtaggagt actatttata gctattggat taatcttgac attcattgaa
    14761 ataaaaggaa atttcccttc tttttatggt tttggtcaaa attctatagg gaaaaatgct
    14821 gtaggtatta tagcagcagg aattgcttta attttcttta gaaatggcat agatagcata
    14881 gattctatag ctacttatgg tgtattttta gcaatagaac ttgttgtaat agttgcatat
    14941 ttcttaataa gaaaaaaatt tactaaagaa gataaacatt taagaactaa ttaactaaat
    15001 tatctactat aaaattggaa aattaaaaac aaataaaagt ttgtttttaa ttatttaaaa
    15061 tccaaatttg attattttta aagaaactat gttctgtata aaactagaat gtggtttctt
    15121 ttttatgtat aaaatatttt ttagcaaaag ttaaaaggtg ttttataata taaaatagtt
    15181 aattgtagat gttaataaaa gaaaattatg tatatttcag ataaagataa gagagtatac
    15241 tatattttaa ttcttttttc aataaagctt attgaaaaga actttaactt agaagagtat
    15301 caccaaattg cagatacaat atcataagca gttatttatt gacaaccctt tttaataaat
    15361 atatcatttg aagtatactg acgaaaagga gttgaataat aatggacatc ttattggttg
    15421 aagatgataa gaatattcga gaaatggtat acgattttct gattagtgag aattactctg
    15481 ttaaaactgc cattgatgga aatacggcta ttgaaatatt taaaaattat tcatttgata
    15541 ttattttact ggacttgatg ttaccaaagt ctagtggttt tgaagtatta aaatatatac
    15601 gaagtgtgag tgttgttcct gttattatta ctactgcgaa agatagtgac acagataaaa
    15661 tgctagggct taatcttggt gcagatgatt atattacaaa gcctttttca atcgtagaat
    15721 tgcttgcaag aattaaagct aatattagac gtgcaacagt gtacagcagt tcaagaaact
    15781 ctcaagatat ggttattcag tataaagatt tgattataaa catatcaaaa tatgtagttt
    15841 caaagaatgg aattgactta aacttaacac atacagaatt tgaaattgtt aaattactag
    15901 cgactaatca aggatgtgct ttttcaaagg aacaattata caacgctatt tggaaagaac
    15961 cttattatgg aaatgaaaat gtgctaaata ctcatattaa caggttaaga aataaattgt
    16021 ctgatggtat agaaaaaaat aattatatta aaactctttg gggaattggc tacaaaatgg
    16081 aggaagaata atggagttat ttttagttgt aatttcgatt gtactatttg ctctctactt
    16141 aaaagaacga aataaatcaa agaaaatgga aagtgattat aagtgtatca attcaagact
    16201 tcgtgacata acaaatgatg atgaaattaa ttatatttta gtaccatctg atatttcgat
    16261 tgtaaaagaa acagcagtag atataaataa acttcttgaa aagttttaca gcaggcaaat
    16321 taattataat agaagtgaaa aagcgatatt gcaaatattt acaaacatat cacacgattt
    16381 acgaactccc atcacagtat taaagggtta tattgaaatg ctatatcttc aaagtcaaaa
    16441 agaagaatta tcttcttcaa tgagagcaac tgtggaaaaa atgcaaacaa attcaaatga
    16501 gcttgttaat tcaataaata acctgtttaa tatggcaaaa atccaatctg gagatatgat
    16561 attaaatctt caaaaatcca atctaacaca attatgtcat gagattattt tagagtttta
    16621 tgatttgcta gataaagaaa actttaatgt tgaagttaat attgaagata gacctatata
    16681 tgcaaatgtt gacacagaag cattacaacg tatactcaaa aatttaattg ataatgctat
    16741 aaaatatggt tcagatggta gatttttagg gatttcacta tatgaaaagg aaaaacatgt
    16801 ttttatagat attgaggata aaggttcagg tatttctgaa actgaaaaag agcatatttt
    16861 cacaagagct tatactgctg acagaaaaaa aggcaatggt ttaggtttgg ctatttctca
    16921 agggcttgca aactctatgg gaggttcaat ttatgtaaat agtagaccta atgtaaaaac
    16981 agtttttacg gtaaaattga aaagttagaa aaaagttaga tttaaaagag agaaaagaca
    17041 attttatttt gtatactgtt tttagaaagg agggagtatg atgaactata tcatagagac
    17101 ccatcaatta aagaaaatat ataaagataa agctgttgtt aatgctgtta atattcatgt
    17161 gaaaaaggga gaaatttatg gatttgttgg accaaacggg gcaggtaaaa gtacagtaat
    17221 gaaaatgttg ctaaatcttg ttaagccaaa ttctggagaa atagttatgt tcagtaagaa
    17281 agtggaagaa actgattttg aaatattaaa aaagattggt actattattg aaaatccgta
    17341 tttatatgag aatttgactg ctaaacagaa tcttgattta cactgtgaat atatgggtta
    17401 ttataacaaa gaacatatat cagaggtatt ggaatgtgtc ggattgtcaa agcaatcaaa
    17461 caagaaagtt tcaaaatatt ctttagggat gaaacaacgt cttgcaatag ctagagcaat
    17521 tcttactaaa ccagaattat tgattcttga tgaacctata aatgcactcg acccagaggg
    17581 gataagagaa atgcgagaat tattccgtaa gttaaataca gattatggaa taactatatt
    17641 tatttctagt catattcttt cagaggtaga acaaattgcg gacactattg gaattattca
    17701 agatggtaaa cttattaaag aaatttctat gtcagatata cacaaatatc aaacagatta
    17761 tgttgaagta gatgtagata atgtggagct tgctggatac ttgttagaaa aagaatttgg
    17821 aataaaagac tttaaaatta cttcggaaag ttgtattgaa atatatgatt tacgaaaaga
    17881 tgtaaaagaa atatccaaaa tatttattca aaatcaaatt ggtataaata gcattggacg
    17941 taaacaaagt tctttagaag attacttctt ccaaactaca ggtacaggag gtaaagaaac
    18001 actatgatac atttaatgaa actagagcta aaaaaagttg ggctaaaaag atatttttta
    18061 ttttcaatgc tggggatttt cttatgtatg ttttttgtct ttactggatt gaatgataaa
    18121 tctacttcaa tatatgatta tgatgttaca tttaggacaa tcagtttatt tttctgtttt
    18181 tactatatta tattatttgc tgtgttgaat gtggcatata taataaatga atatacaaat
    18241 aaaacaatct tgattttatt ctcttatcca cttgaccgta aaaaacttat tttatcaaag
    18301 ttacttttga ttacgactct tatgatatca tcaatgatag ttggatatat ctgttgtttt
    18361 acattcgttg ttgtgttgga taagtatttt aatttagtta ttggagattt tcatatttca
    18421 attttatctt attggatacc aggagcaatt aaaagtatta ttatattttg ctcattaggt
    18481 atatggacat tcgttgttgg aatgataaga aaatcaatac ctgttaccct tgtcagttca
    18541 attattttta tcaatttaag acaatttatt ttagctggta caaatacaac tcaagacagt
    18601 ttgatttctg tttttattat agttggtata actgtgattg gtatatatta tatactaaat
    18661 cataaagtta ctgaaattga ctagatactg tggctaggaa ggtagttatt aattgtatct
    18721 tcttgggata ataatgattt gctattatat cagctattat taatattatt agagttttaa
    18781 taatattgca caaccatttg aagttgagcc aaagcttgat gaattaattg aatggtacta
    18841 tagtcagagt gaagtatcta ttaaagttat agctgaattt cattatagat ttgaattgat
    18901 acatccattt caagatggta atggtcacat aggtagattt gttatgctaa aacagatgtt
    18961 agaaaataat cttcctataa aaattgtatc ttgggatagt gaggacttgt atagaaactc
    19021 cttaaattct tgtagtttag gtaattatgt ccctttaatt gaatatttat caagtttaga
    19081 agattttaga gaagtatata aaatgttatg gaaataattg tttgcagcaa aaaaaaattt
    19141 tatataaata tatttttatc tatgctattt aacgctaatt tcttagttat tcttagcttg
    19201 gactatatcc actattttaa ctatataaaa tagtggatat agtttaacta tctctttata
    19261 actattctta tgtatcttag ttgtttctta atatggggac agttcataaa actaaaagtg
    19321 atttttaatt ttatcattta taatttacca ttacatcaga aaaatgctta tcattagaat
    19381 tttcataaaa gtcacctatt tttttcaatt aactaaatca attctattag tcttaatctt
    19441 tcgtatttca aattgataat ataagaaaat aaaaaataaa aaattttaaa ttttttattt
    19501 attgcgaaaa aaataaaaag gtgctatact ttttgtaaca tattattcaa attattaaga
    19561 gatagtaaac atttatagtt taatttgtag tacactagca tgatttgcag aacaatgaat
    19621 taatctatag tataatagtt taatttaaag tacaacgatt taatctatag tacactagca
    19681 tgatttgaag tacaacgatt taatctatag tacaataact tgatttgcaa tacaatgaat
    19741 taatctatgg tataatagtt taatttgaag tacaatgaat taatctatag tataatagtt
    19801 taatttgaag tacaacgatt taatctatag tataatagtt taatttgaag tacaatggtt
    19861 taatctatag tataatagtt taatttgaag tacaacgatt taatctatag tacaataact
    19921 tgatttgcaa tacaatgaat taatctatag tataagagca tgatttacag tacaataatt
    19981 taaattgtag tacaaaagta ctatcaaata agaatttcta ctttaaaaat attactaaaa
    20041 gtaattaaag tccagtaatt caatataata tggcaaaaga atagaaataa ggtgagagta
    20101 gtgaaagtaa agtcaaattt agatgaaatt ttatatcata agattattga aagtcttatt
    20161 cgtggtgaat actctgtagg tcaaaaaata ttactaaatg acctttgtga aaaatttgaa
    20221 gtaagcagaa caccagttgt acaagcagta aaaatgctaa ataaagatgg agtgcttact
    20281 attatgacaa atggtaaagt gtacgtacca gagtatgaat atgatatggt aaaacaagtt
    20341 tgtgaaacga gaacactgat tgaaacatat gctttagaaa aaatgatgca agaagaggaa
    20401 gaggtttttc aacaaaagct agatgtaata aaaagatact ctgataaatg cgaggagtac
    20461 tatcgtcaag aaaaatctgt agaacttgca ctagcagatt tggaattaca taaagccatt
    20521 gtagaagggg caaataatga gattttaaat gatgtatatg ttggtataca aggaagattt
    20581 atagtagtga actatttaat tcgaccatta aaaaatcgta attatgaagg aacagtacaa
    20641 gaccattttg aaatattaaa attcattgaa gacagagata caaaaaaagc agtagataaa
    20701 ctaagaaatc atattcaagg aactattaaa agattctgtg aagatgaata ataagttttg
    20761 aagttactat atatacttat ctattaagtt gctaaatgta gtctaagtat aatctaatta
    20821 tagtttaaac ataatctaaa tataatctaa taaatataat ctaaatatag tgtaaataag
    20881 tctaagtatg aattaaatat agattaagta tggactaagt atagattaag tatagattaa
    20941 gtatagatta agtatagatt aagtatgaat taagcatgga ttaaatatac tttaaattac
    21001 aaatattaca aggaagccag aaggcttcct aaaaaaataa cctttataaa attttttatt
    21061 ttaaatttaa aattttttat tttaaattta aaataaaaaa tgaaagaggt ggtagggagt
    21121 ttgaaaaaaa ttactaaaga aaggacagaa aatactatga aaaagctatt tacgagtgaa
    21181 acatttttgg aatatcaatt tataagtgat tgccaaatat caccagatgg aggatataca
    21241 gcatttattg taaaaaaagc tgatatcaaa gagaatggtt acacaagcca agtttatata
    21301 ttaaacaata aaactggcga attaaaacaa ataacgtcta taaactctgt tggagcatat
    21361 gcctgggaag atgaaaatac tatcttgttc cctgctttga gaaatgaaaa agtaaaagaa
    21421 gctgtcaaaa acggtaagca atgcatgagt tactatgctt tatctttaaa tggtggagaa
    21481 gcagaagaac tttttagact ccctatcaaa ggtggtaaat tgaatcctat aggaaaaggt
    21541 ttgtatgcag ttattgattc ttatgacaat gaccgaccta ttgtagaggg attgccagaa
    21601 gaagaacaac agaaaaaaat aaatgcttat aacaaaagac attatgaaca tttcaaagaa
    21661 attccttatg ctgtcaatgg ggagggatat attagcagaa aaagaaaacg cctatatata
    21721 tacgacagta atataaatga gttgaaggca attacagcac ctatgtttaa tgttgtaggt
    21781 atgaaaataa gtgatggaaa aatcttatat atagggcaag agtttaaaga tgtaaaaggt
    21841 ttgaaaaatg gggtctatgt atttgataca aacacaaaca caaatgtctg tatattagaa
    21901 aaagataagt atattataaa aggttttgaa ttatatcaaa atcaagtgat actaaaccta
    21961 actgatgctt tatcttatgg aaatggagaa aatggagatt tttatactat tgatattgat
    22021 acgaaagaaa tgaaacttct ttcagggcat caacatcatt gtattggaaa tacagtaaca
    22081 tctgatgtta aaatgggtgc tggtcagaca acaaaggtag atggagaata tatttattac
    22141 acttctacag tagatatgga ctgcattatt gaaagaatac atattccaac aggaaaacag
    22201 gaaaaagtaa cacagacagg ttcagttgat tttatagatg taaaagatgg caatattgta
    22261 tgtgtgggtt gtttaggaaa tggattacca gaagtttata cagtagagaa tggaacattg
    22321 tgtaagaaaa cacatttaaa tgaccatatt ttagaggaat ataaaatttc tgtgccagaa
    22381 tacatagagt caaaaggaag ttctaaatgg gaaatacaag gatacgtata taaaccagta
    22441 gattatgagg tggggaaaaa atatccagct gtattggcga ttcatggagg accaagattg
    22501 acatatggac catattttat gcatgagata caggtattta caagtgcagg ttactttgta
    22561 ttcttctgta acccaagggg gtctgaaggt cgtggcaatg cttttgcaga tattaggaaa
    22621 cagtttggag atattgatta tatagatttt atggaattta cagatactgt acttgaaaaa
    22681 tatacagaca ttgataaaac aaaattggct gttgaaggtg gaagttatgg tggatttatg
    22741 acgaattgga taattggtca tacaaaccgt tttgctgttg cttgtgctca gcgttctatt
    22801 gcaaactgga gtggcatgga gggtacaaca gacattggtt attatttctg caaaggacaa
    22861 acaggtgctt ctcatatgga aaaccacgag cttcaatgga aacagtcacc tcttgcttat
    22921 gctgataaat gtgttacacc gactttattt ttacatggtg aaaaagacta tagatgctat
    22981 atgcaagaag cattccagat gttttcagca ttgaaaattc atgggtgtcc tacaaaactt
    23041 tgtctatttg aaggagaaaa ccatgaactg tctcgttctg gtagaccaaa acaaaagcta
    23101 caaagattag ttgaaatgct agattggttt tcggtatata taaaaaaaga taacatagga
    23161 cagtagaaag gagaatataa aaatggaaaa aataaagatt gaaagttcag atatttttga
    23221 atatatattc cctcatgata tttcttgttc acctgatgga aagcatattg cttatattat
    23281 atcaaatatc aacgaggaaa aagactgcta tgaacatgac ttatatgtga tggacatcaa
    23341 aacagaaaaa caaatacata tgactcaaac aaaagatgta acatcattta gttggatttc
    23401 taatacagaa ctccttttta catctaaaag aaataagcca aaatcaggta caacagattt
    23461 ttacactatt tctatagaag gaggagaagc aaaaaaagca ttttctattc caaaagcttg
    23521 tagcgtacct gtatcacttg gaaataaatt gtggttactg acaacaaaaa atccaacgga
    23581 ttctaaaaaa tcagaaccag atagggcagt agagggtgta gattattgga catttacaga
    23641 taaacctttt ataagagatg gagaaaattt ttctcaaaga agacgtgtaa cattagaatt
    23701 atatcaagaa ggtgaaaata taacaaaagc cattacacca aaattttgtg aagtagcagg
    23761 tgtagacgtt tcttctgata aaaacagaat tttatatact ggtcagattt atgaagattg
    23821 tgcaactcct ttttctggac tttgggagta tcatatagac agtggtgaaa ccaaagaact
    23881 tgtaccacaa ggaaagtacc aaataagttt ggcaaaatat attggcaaag ataaagtaat
    23941 gttgcaagct tcaacattag accgttctat cacacagaat catgatattt ttatacttga
    24001 tttgagtact aatgaaataa atatgattgc tagtccagat ggtatgtatg ctacattgct
    24061 ggatgtagat gcagtatatg gtggtggacg tagtaataaa gttataggag ataaatttat
    24121 tggtgcaaga atttgcagaa ctatgacaga atttaatgag tttgatacaa agacaggtaa
    24181 tatacgtatc atcacaaaag tagatgcttt tacatctttt gatatttacg acaacaccat
    24241 gtacacagta atgttgaaag attatgagtt agcagaaata tatagcattg atatgactac
    24301 aggtacaatg aaaaaaatga ctgctttttc taaaccatat ttagatactc ataaggtttc
    24361 attacctgaa aaattgacgt ttgtagcaaa aaataaagaa gaagttgatg gttttgttat
    24421 accacctata gatgctaaag aaggcgaaaa atatcctgct gtattgttca ttcatggtgg
    24481 gcctaaatgg gcatatggct atatgtttac acacttgaag cagtgtgtaa catcaaaggg
    24541 aatgtatgtg atttattgta accctcatgg tggtgacggt tatggtgaaa agttcttaga
    24601 aatggtagaa agatgggggt atgttgacta tgagcatctt atggaatttg tagatacttg
    24661 tattgaaaaa tatcctggga ttgatgcaga ccgcttaggg gttgcagggg gaagttacgg
    24721 tggttatatg acaaactgga taattggtca tacagaccgt ttcaaagcag cagcttctca
    24781 aagaggtatt agtaacttga ttacagcttc tttaattatt gactttggag atagaattat
    24841 gaagcagact tgtggagata agacgccttg gaatcatgag gaggttcttt ggaatcattc
    24901 acctattaaa tatgtgaaaa atgttaagac accaacattg ttcttacata gcgataggga
    24961 ttatagatgt tttatggggg atactttcca aatgtttaca gcattaaaac agcttggtgt
    25021 agatacagaa atgtatttgt ttcacggaga tacacatgga ttgtctagaa atggaagacc
    25081 atctaataga attgcaagag caaatgctat tgtagattgg tttgaaagat atttataata
    25141 agggggttat tctatgagtg atatgttatt atggtttagt gtcgtattag ttttatttgc
    25201 tattggggat ttaattgcaa gcaaaacaaa agcaaaagta tcagctgtat ttgttacact
    25261 acttttattt ttgattctat ttgtcacaaa agcaatacca gctgatatta ttgaaaaagc
    25321 aggtatgacc gcagcagcta gttggagtgt tccaatgatt atgtttagta tgggaacaat
    25381 gttgaatgtt aaacaattta tagacgaatg gagaacagta ttgacagcat ggcttggaat
    25441 tgtagcagtt atagtctgtg tctcattatg tattcctttg tttggaaaat caacagtatt
    25501 gacaagcata ccagttataa atggagcttt acctgctact actattatga cacaagcagc
    25561 actagaaaaa ggactgacac ttgcagcagc tacagcaaca gttgtatttg caattcagaa
    25621 gtttattggt acaccaatag cttcaagagc agcgttacaa gaggcaaacc gtcttttagt
    25681 agaatatcat gaagcaaaat caaaaggcat tgatttagca aatgttgata ctgataagaa
    25741 agaagcagag aatacaggca caaaagtaaa acaagctttc tgtgaaaaat acgataaata
    25801 ttattctaca aatgtttgta tattttttat agcactattc tcttatctag ggtatgaact
    25861 ttcagagatt attcatgtaa attattctat tgtatgtctt gttgttggtg ttattgtaac
    25921 acgtattggt attgtaccaa aagacatttt ggaaaaagga aaaatcaagg gatttatcaa
    25981 catggttgtg tttgcagctg ttattccttc tttagcaaaa gtttctttga cagatttaat
    26041 tagtcttttt gtaccaattg tgggtatgtt tgcagcttct atcattggta tattccttat
    26101 gatgaaggtg ttaccaggtt ggaaaattat cggttctaaa cctcttgctt ttggagtagg
    26161 gttttgtcag atgttgggat tcccaactac atatttaatt tcaaatgaag tgtgtaatgc
    26221 tgttggagaa acggaagaag aaagagcata tttgatgtct aagattatgc ctaagctggt
    26281 agttggtggt atggcttgta tgatttctat tgtggtagct ggtcttatgg taccaatgtt
    26341 gtagataggt ttcatagtta aaaaagtggt gttaatttat aggagaagct aaaaagtagt
    26401 attaatttat aaaataattt tatattagtt aatttgttat aagaatattt tctttttata
    26461 attataattt tgattttata agagagcaga ttttttattt gctatgctaa tagttataat
    26521 ttgtttttat ttgctaaaat gcaactttaa tttgatttat gtataatata gggtatttaa
    26581 taatattttt gaagaatttt tataaaaaat taaaaagagg agaaaaaagg gagtgccaca
    26641 aagtgaactt tttagttcta aggcactctt ttttgtacga aatcgaatat attttcaacg
    26701 ttttaaaagt gagaaagaga cttatctcta gtttgagata gccaatttta attattaaaa
    26761 ttattttttg ttttatttat caaagagtat ccgtgtttta gaagttagta ttttttattt
    26821 tatatataca aggttttccg tttctaatgt tttccttttt aaaataatta gggtattcaa
    26881 ttatagtaaa aggtggatgg tattttggag tgatattatt taaagcacag tattgaatgt
    26941 tgaaatcctc acattttaga gtattatctt ttgtaatcaa aaaaatcttc tatacttata
    27001 gcaaggttat ttctgcaaat attccataca taataatatc ccaatttaaa ttttttttat
    27061 atagagttta cctctagtct acactcttga ataactcttt cctctatcca aattcttata
    27121 aattcatccc atttattact atctatttat tactatctaa attttttagt atgtttgtaa
    27181 ttagaaatgg atttattcct ttatgttttt tataaatagt ttataactta atttatcatc
    27241 aaacaaatca ttcatacagg attacttttt cttttagata ttcaattctt acttttaata
    27301 aatatttaat acattctatc ttatgtggtt ttaaaaagtg tttatggcta ttaacaatct
    27361 ctaatatttc attcatattt attttgtcat agtaatattt tacatctttt atattgacaa
    27421 aaaagtgctc taagtgtata gtgtgtatat aacaacatca cactgaagat gataaaaagg
    27481 gggtgataaa aaatgaaagt gctcatttct aacacatcag ataagccatt ataccaacaa
    27541 attaaagagc aaattaaaga agcaatattt actgaagaac tgaaagaagg ggatgcaatg
    27601 ccatccataa gaaattttgc taatgattta aaagttagta ttttgactat tagacgagtg
    27661 tatgaagaac ttgaaaatga aggctttctt acacgccaag ttggaatagg aacatttatt
    27721 tcaactggaa atttagaaat actaagagac tcaaagagac gtatagttga acaaaaaatg
    27781 gcagatatga ttaaggatgc aaaagcacta ggaattacac agatagagtt acaagaaatg
    27841 atggatattc tatatcagga ggattaatat ggaaaatatt ttagaagttt ataacttaaa
    27901 taagacttat accgattttt cattatctaa tataagcttt gcattaccag aagattgtat
    27961 aactggattt ataggtgtta atggagcagg aaaaacaaca acaatccgtt cgatattgga
    28021 tgtcgtaaag cgtgatagtg gaaaaataaa aatctttggt aaagatttcg atggaaatga
    28081 gaaggaatta aaaaatcgaa ttggagttgt atttgatgat tcatatttct atgaggagtt
    28141 gtcaatggca gaaatgaaaa gtattattgc accttcatat gataattggt gtgaagaaga
    28201 ttatcaacaa aatatgaagc gttttaatct taacccaaaa caaaagattg atacactttc
    28261 aaaaggaatg aaaatgaaat ttgctttagc attagcatta tcgcataaag ctgagttttt
    28321 aattatggat gagcctacaa gtggcttaga cccactaatc cgtagtcaga tacttgacat
    28381 actaacagaa tatatgaaga aatgtggtcg tggtgttttc ttttccactc atataacatc
    28441 tgatttagac aaaatagcag atatgattgt tatgattgac aatggacgta ttatattaga
    28501 gcgtgaaaaa gatactctat tggacgaaca tagaaaagta aaaggagata ttcaatttct
    28561 aaatgatgaa accaaaaaat tatttttaaa tttagaaatt accggctatg gttttatagg
    28621 gattacctca aaaattaatg aagtgcaaaa aaatatgcca gatattttaa tagagcgtcc
    28681 tacaattgaa gatattatgc ttgcatatat tgaaaggaga gagtaattat gttgattcat
    28741 ttagttaaaa aagatattct gattgtaaaa aaatatgtat tgttgatatt atttattgca
    28801 ataggaatcc cattatttat attgtggcgt ttacctccat ttgcacaaat attgggattt
    28861 gtactatcca ttatattttc agaatttatg ctgtgccagt atctattatt aaaggagagt
    28921 caatattcaa aagcatctgt attactttgt tcaactcctt atcctagacg tggcttagtt
    28981 caatctaagt atgttttatt tgcaatggta tttatctatt gtacattagt ttactggatt
    29041 gaaaatttac ttattccaca aataggaact tttgacttaa catatatttt gattgtttta
    29101 ttaataagtt ctattattta tggagtttat atgcctattc aatataaatt aggatatgaa
    29161 acaacaaaat tctttttcgt ggtgataatc atggcttcat catttgtatt accattaact
    29221 atagctcaca gcaattttga aattccattt atatatcagt atccatccat gatagtgaat
    29281 attgtattgt tccttttaag tttaattata ctgttagctt caatgtttat ttctattaaa
    29341 atttttagta ataaggagct tgtataaggt aagggggact tttatatgcc acatttacca
    29401 gattgggctg ttttactttg tatcttactt ccaatagtat ataaagcttg tcagatattt
    29461 aaaagtaaaa aatagagtat atatttatat tgccattttt attgagtgaa gttagatggt
    29521 atgaaaaggt tacttgaaaa taaagttact tggtgtggga gagtaacatc ataatattat
    29581 agattatatg tttcttgtga atcaatttgt attttttaat agggaatatc cagtaatttt
    29641 gttttccatt gattattttt caattatgag tatgattgtg tgtattgtat accatctttt
    29701 aaggtgtttt taaaaaatta tatcgtcaaa atataaatct aaggaatcct ataaataaag
    29761 ctttttaatt ttagaaaact aataaaaagt aggacgttaa taaaaagaag ctgtctcaaa
    29821 atagagataa gcttcttttt cattgctgaa atgacgaaaa tataattgat ttaatataaa
    29881 aaagagtgct ttatgaacta tttattttga acagtagata cacttgcact caatttagtt
    29941 actcctaagc tttatgaact aaaagtttat tttgaagctt atttttatta aaagagattt
    30001 tatttttcta aataatcatc tatatacagt attgcgtttc ttttatttat tcataattta
    30061 ttttcttatt aaagtttttc tatattcata ttttctatat tactttactt ttaattttat
    30121 acgaattatc aaaaataaaa tagttattag aaaaaaataa aagtaattgc aaagcttgca
    30181 attacttact tctatattaa ttactatacc ataaaataac aaaaaaatca agtcgagtaa
    30241 tccttcaact taaatgatat actaggtatt aataattttt aattaataaa atataactag
    30301 aggaaaatct acattttctc aatttcttta attaaattga cctctaatta agtaattata
    30361 aggagaaaaa ttatgaattt agcaaaggga ttagatgttt taaaaatttc atcaaatgta
    30421 ttcggtgaag ataaagttat gtatattcct gtaatctaca cagaagatga tgcaacactt
    30481 attgacacag gtcttccggg tcaaggtgat ttaataattg atgctcttaa taaaagtaac
    30541 acgagctttg ataggttaaa aaatataata attactcatc atgatataga ccatatagga
    30601 aacataaatt atctaagaga aaaatctaag aataatatca aagtatatgc atacaaaagt
    30661 gaaatcagct atataacagg agaagaaact ccttttaaac tttatatgtt ggaacaaatg
    30721 gtagataaaa ttgatgataa gatgcttagt atgctaaatg ttatgggact tggatttaaa
    30781 tcatcatata ctaaagtaga tgtgtcatta gataaccatg aaaaattgaa tctaggtgag
    30841 gaaatagaag ttatacatac aggaggtcac actagaggtc acatatgtct ttatttaaaa
    30901 gagtctaaag tacttattgc tggagatttg ttacaggtag aaaatggaga acttaagcct
    30961 gttgatgtga tgtacagcaa caaacaagag ttaaaagatg ctattaaaaa tataagtaat
    31021 tatgatatag aaacgatagt ttttagtcat ggtggattat atcaaagaaa cataattgga
    31081 acattgaaaa acctaattat tgagtagtac tatatgattt acaataattt cttaaattac
    31141 ttaaaattat atctaaagat gtagaatcaa aattaaatat aagtaataag aattttgctt
    31201 taaaattata cttaagtgtt aaggatgata cgtagtatta caagtatttt agaatataat
    31261 tttttatagt aattttaagg ttctacaata cttcagttga aaaatattta acagcatagt
    31321 ataataggaa agaaaatact ttaaataaac tttagcatac aaagtgaaga aaaatattta
    31381 aattatatat aatattgtag agtgaggtaa aatatttaag ttatatatca taatgcagag
    31441 tgaagaaaaa tatttagata atgtaccata atacaaagtg agtaaaaata tttaaatcat
    31501 gtatcataat gcaaagcgaa gaaaaatatt taaataatgt accataatgt agagtgagta
    31561 aaaatattta aataatgtgt tataatacaa agcgaataag attatttaaa gcatgtgtta
    31621 taatacaaag cgaataagat tatttaaagc atgtattata atataaagtg agtaaaaata
    31681 tttaaatcat gtatcataat acaaagtaaa gaagattatt taaaccatat atcataatgc
    31741 aaagtgaaga aaaatgttta aattatgtat cataatataa gcagagtgaa gaaaaatatt
    31801 taaataatat atcataatgt agagtaaaga aaaaatttaa atcatgtatc ataatgcaaa
    31861 gtgaagaaaa atgtttaaat tatgtattat aatataagca gagtgaagaa aaaatttaaa
    31921 tcatgcatca taatataaac agagtgaaga aaaatattta aataatatat cataatgtag
    31981 agtaaagaaa aaatttaaat catgtatcat aatataagca gagtgaagaa aaaatttaaa
    32041 tcatgcatca taatataagt agagtgaaga aaaatattta aataatatat cataatgtag
    32101 agtgaagaaa aatgtttaaa ttatgtatca taatataagc agagtaagta aaaatattta
    32161 aatcatgtat cataatgaaa agtaaagaaa atcatttaaa ttatatatca taaaaataat
    32221 atgaaatatt gaacactcat aatattagag actttaatat tttaattgat aggttatatt
    32281 atttataaca ttaaaaatac aatttacata aaatagacat atgaaaaata aaaaattata
    32341 taataattat gggaatgagg ttctcccttg gatgataata tcctaaactg ccaatgagct
    32401 gatgacttct atgatatcat agatgccacc agcttttttt gttgtttaaa tcgataaaat
    32461 ggaggtgaat tacttactaa atttttattt tttaaatttg aagaaatatt taatcaataa
    32521 aaaaaatagt agattatatg ttaattattt tattaagaat gggttaagag tgtacctata
    32581 tcctatcaat taaaaaaaca attacgatag tcattacatt gactacagtt gatgcaataa
    32641 aactttcaaa aaatcttatg atgcaaatag aaaggaatta aaatgataga aaaatttaaa
    32701 actttaatat ggattaaaat gataataaaa attaaaagcg tttataaaac atatggtgga
    32761 ctatttttgt taggactcat aggtatacca attggtgcaa ttataggtct tatagacacc
    32821 atatttggaa cggttcttct aaaagttaca gatattcgag aaacatatcc aatgtatctg
    32881 ataccatttt tagcagtagt aggagttgtt attgcttatt gctattttaa atttggagga
    32941 aaaagtagta aaggaatgaa tctaatattt gaggtagggc atggagaaga agaaattatt
    33001 cctttaagat tggttccatt tataatatta ggtacatggt taacccattt atttggtggt
    33061 agtgcaggac gagaaggagt tgctgttcag attggtgcaa ctttttcaca ttgggtaggt
    33121 aaaaggttgc ctataaaaaa tgcttctagt atttttctag taactggtat ggcagctggt
    33181 tttgcaggat tatttgagac accaatagca gcaatactat ttgctatgga ggttttggta
    33241 gctggttcac tggagtatca atcgcttttt cctgcgttta ctgcttcttt tacagcaagt
    33301 gcagtatcaa aagctttagg gttagagaaa ttttcttttg cactttcttc taaagttgta
    33361 tttgacttgt caatattttg gaagcttatt gttttaggaa ttatttttgg aatggttggt
    33421 ggagcatttg catggtgtct gaaattgtca aaaagaaaaa tagggaatag attaaaaaat
    33481 cctatgataa gaattgctat tattggagta tgtcttagtg tattattcct tttattttat
    33541 aaaggaagat attcaggttt agggacaaat ttaattcaaa atagtttcta tggtggagaa
    33601 atttattcat ttgactggct gttaaagttt atacttacaa tactgacttt gtcagcaggt
    33661 tttcaaggag gagaggttac acctttgttt tccattggag ctagtcttgg tgtattgtta
    33721 gcaggatttt ttaatttgcc aattgaatta gttgcagcgc ttggctatgc tagtgtcttt
    33781 ggtagtgcta caaatacttt ttttgcacct gtatttatag gggcagaagt ttttggatac
    33841 agctatttac cttatttctt tgtagtatgc gctatttcat atatatttaa tatggataaa
    33901 tctatttatt cactacaaaa aatttcaaca aaacaataaa taaaacaaca taatgtatga
    33961 ttagaagaga aagaatatta gagaaaggat agggtaggaa tatgttgaca agtttagctt
    34021 tgattttttt attaggaatg gcctcgggag gtatttttaa gaggataaag ttacctaact
    34081 tattgggaat gttacttaca ggaattatat taggtccata tgttttaaat ttgattgata
    34141 attcaatact agatatttct tctgacctta gaaagattgc attgattatt atattaacaa
    34201 gggctggatt atctttagat ataaacgatt tgaagaaagt gggaagacct gctgtactta
    34261 tgtgctttat tccagctact tttgaaattg tcggaatgat agttttagca ccaaagttac
    34321 taggcgtttc tatattggaa gcagcagtca tgggtgcagt agtaggagca gtttctcccg
    34381 caattattgt acctaaaatg cttaaattaa tggaagaagg ttatggtaca gaaaaaagta
    34441 ttccacagat gcttttagca ggaacttcta tagacgatat tttcgtaatt gtgatgttta
    34501 cagtattcac aggattggca caaggaaata gtatatcagc tattagtttt ttacaaattc
    34561 cagtatcaat tatattaggt gtaatagttg gagcagtgat tggaatctgt ttagcagtat
    34621 tttttaagaa gattcatatg agagattctg ctaaaggagt gttgctttta agtatctcat
    34681 ttttaatgat aagtttagag actgctttag agggtattgt gccattttct ggattattag
    34741 cagttatgag tattgggatt ttccttcaga taaaatatcg tgtagttgca agaagattgt
    34801 ctataaagta ttcgaaacta tgggttggtg ctgaaattct cttgtttgtt ttggtagggg
    34861 caacagtaga tataagttat gcatttaaag caggaattgg agctgtaatt ttaatatttg
    34921 gagttctttt attccgtatg gtaggagtat tcttctgcct tattaagaca aatttgacaa
    34981 taaaggaaag attgttctgt atgattggct atattccaaa ggctacagta caggcagcaa
    35041 taggaggtgt accacttgca atggggatgg catctggaca acttattttg acgttagcag
    35101 ttctagctat acttataact gcacctcttg gagcttttgg aattgatgta acttataaaa
    35161 aattattaac ttctgtaaaa ggcgagaata agtaaaaata aagattattt taactggtaa
    35221 gttatatttt ggaaaaggat tatactattg aatacaatat aaaaaaatca tttgggagat
    35281 taagaaggta gaagttaaga acagatttta aggtatgtta tgattattag aattgatttt
    35341 gtgaaattat tattgtaata tttaattata tagataaaga agcggagtga taactatgtg
    35401 tttaaaaaaa ttatcaaaat tagagttagt tattatgaaa tttatttgga atttagatat
    35461 aaaaaccaat tcatatgaga ttattgatta tatgaaagaa gaacataatt taccagaaaa
    35521 agtagcttta aaaactttat caaaactatc aaagaaaaga ttcttatatg ttcaagaaac
    35581 aggcaagtgt atgtattata cagttgcaat aaaagaaaag gcatatttag agtttatatc
    35641 aagaaatgtg caaaatcttt tgaagaataa ttttataagg aatttattag tatcatttca
    35701 cgaagaggag ctaacagagg aaaagataaa gtcgttagaa aactgggtag taaattggga
    35761 agaagcttat gtataaatgt tattattttt attacaattt agataatttt ggttttgtaa
    35821 gctctgcaac tatttttaga tggttgcaga gtttattttt attttttatt cccttaagca
    35881 atacttaaaa gtaaacgcat ttatatttac taacttcaat tacttataat acttaaatta
    35941 ctttttaaaa atattttgat atgtcatctc tatagtaatc tagaacttgt ttctattctt
    36001 tatataaagt ttttatgaat gatatatata atattcgttc atttgattaa aaataacaaa
    36061 atattaaata attctactct gatagtttgt taaaa
//
LOCUS       DAMKNB010000034        35889 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.036, whole genome shotgun sequence.
ACCESSION   DAMKNB010000034 DAMKNB010000000
VERSION     DAMKNB010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 35889)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35889)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35889
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.036"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            complement(359..871)
                     /locus_tag="PC494_001896"
     CDS             complement(359..871)
                     /locus_tag="PC494_001896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HDF3912397.1"
                     /translation="MLEVIKNRHSIRTYIDKNIEEDKITEILKSAMQAPSSKNAQPWE
                     FIIVDDKELLKQLSKSQHRAKHIEFAPLCIVVLGNRDKFLKPGKWIQDLGACTQNLLL
                     EVTNQGLAACWAGVFPKNKVVNKVRQTLDLPVKLVPYALISIGYSEEKNEFIDRFDEN
                     KIHRNVYKNR"
     gene            1321..1797
                     /gene="purE"
                     /locus_tag="PC494_001897"
     CDS             1321..1797
                     /gene="purE"
                     /locus_tag="PC494_001897"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HDF3912398.1"
                     /translation="MKVAVVMGSKSDYPKLEEGIKLLEKYGIEVVARALSAHRTPEQL
                     SIFLKEIEDDTDVIIAAAGKAAHLPGVIASQTLIPVIGLPIKSSTMDGLDSLLSIVQM
                     PKGIPVATVTIDLGLNAALLALQIMTLKYPKLKEDLKSYREEMAQKVLEDDKNLRG"
     gene            1803..2501
                     /locus_tag="PC494_001898"
     CDS             1803..2501
                     /locus_tag="PC494_001898"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HDF3912399.1"
                     /translation="MLLYEGKAKQVYSTDNENEYVVYYKDDATAFNGEKKAEISSKGI
                     LNNKISTIIFEMLKENNINTHFIKSLSDREMLVKKVEILPLEVIVRNIAAGSICKRVG
                     LEEGVVFDEPIFEISYKNDAYGDPMLNDDYAVAMKLATREELKFLREETLKINELLKA
                     FFLKLNLKLVDFKIEFGKDSEGNIILADEVSPDTCRLWDVNTNEKLDKDRFRKDLGDL
                     VEGYTEVLSRMNNK"
     gene            2513..3880
                     /gene="purF"
                     /locus_tag="PC494_001899"
     CDS             2513..3880
                     /gene="purF"
                     /locus_tag="PC494_001899"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HDF3912400.1"
                     /translation="MCGVLGIYSNKDVTKELYYSLYSMQHRGQESCGLALLDDGEIKY
                     KKDMGLVGDVFKENELSKLKGNIGIGHVRYSTAGGSHVSNCQPLVGSCRKRQLAIAHN
                     GNLVNANYLKDMLEEDGYMFQTNSDTEVILYILARYYKGDIVESLKVTMDYIKGAYAL
                     VIMSQEELVAVRDPHGFRPLVLGKKGDEYIFASENCAIDILGGEVIRDVEPGEIIVVK
                     DGELKSYFYSENYKPVKKSCIFEHIYFARNDATIDNVNAYEFRIKCGERLAQNETVKA
                     DMVVPVPDSGWPGAIGYANASGLKISEGLVKNRYVGRTFIKPTQEEREIAVKIKLNPL
                     STIIKGKSIILVDDSIVRGTTSKQLVKSLREAGAKEIHLRITSPPVAYSCYYGIDTPN
                     RSKLIASSNNVEEMREYIGCDSLKFLDIEGMLDATEHKSTFCKACFDGEYPVKKIDKE
                     ELLSC"
     gene            3874..4950
                     /locus_tag="PC494_001900"
     CDS             3874..4950
                     /locus_tag="PC494_001900"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HDF3912401.1"
                     /translation="MLTYKESGVDIDEGNRAVDLIKGKIKGTYDGNVVGDLGNFSGLY
                     SLKDFVGMKEPVLLASTDGVGTKLKIAQMMDKHDTVGIDLVAMCVNDLICQGAKPLFF
                     LDYIALGKLVPEHIEKIVGGIADGCKMSGCALIGGETAEMPGMYGEDDYDLAGFSVGI
                     ADKEKIVSGNNVKSGDVLVGISSSGVHSNGFSFIRKIFLETYNYKMEQYVEELGMTVG
                     EALLTPTKIYVKLALDVLAKHDIKAIAHITGGGLIENITRVIPKGLGLDINKKSWEKP
                     PIFKMIEGFNAVDERELHKSFNMGIGLVLIVDKENADDVVNFINNRENDNAAYVDKKY
                     SELLEDKAYIIGEVVDSHEGVELC"
     gene            4944..5537
                     /locus_tag="PC494_001901"
     CDS             4944..5537
                     /locus_tag="PC494_001901"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HDF3912402.1"
                     /translation="MLNIGVLISGGGTNLQAVIDGTESGEIKGQVKVVISSKQGAYGL
                     ERAKNHNIKAICETDEDKIIEILKENKIDLVVLAGYLKIISPKLVNEFRNKMINIHPS
                     LIPSFCGAGFYGEKVHQGVIDYGAKVTGATVHFVDEGADTGPIIMQDVVKVNQDDDAK
                     TLAKRVLEVEHRILKESISLFCENKLKLQGRRVFINE"
     gene            5530..7062
                     /gene="purH"
                     /locus_tag="PC494_001902"
     CDS             5530..7062
                     /gene="purH"
                     /locus_tag="PC494_001902"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HDF3912403.1"
                     /translation="MSKRALISVTDKTGVVEFAKELNKLDYEIISTGNTFKTLKENGV
                     NVMQVEDVTNFPEILDGRVKTLNPYIHGGILYKRDKESHVETVNEHKIHSIDLVAVNL
                     YDFEGTLKAGKSHDEIIENIDIGGPSMIRSAAKNYKDVIVVVDIKDYDSIIEKLKTDT
                     MTLEDRKKLSYKAFSTTGRYDALISSYFAGEVGDTYPDILNLTFQKEQTLRYGENPHQ
                     NGFLYSQSNAKNPILNYEQLGGKELSFNNLNDLHGCLEVMREFKDSEEVVSVAIKHAN
                     SCGVGLGKDAFEAYTKCYEADKVSIFGGIVGITSTIDKATAEKLNEIFLEIVVAYDFE
                     PEALEILKQKKNLRILKLAKIENSLQPYEMKYLDGKLLIQDRNNILAEKSENVTKEKP
                     TDAQLKDMEFGMRVVKNMKSNAIAIVKNGQTLALGCGQTSRIWALKNALENNKDKDFT
                     GAVLASDAFFPFDDCVTLAHEYGISAVVQPGGSIKDKDSIEACDKYDMVMVFTGIRHF
                     KH"
     gene            7073..8323
                     /gene="purD"
                     /locus_tag="PC494_001903"
     CDS             7073..8323
                     /gene="purD"
                     /locus_tag="PC494_001903"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HDF3912404.1"
                     /translation="MKILVVGGGGREHAICWKLSKEKNVEKIYCAPGNAGIANVAECV
                     NIGDTNIEELLKFAKENEIGLTIVGPEVPLVMGIVDEFEKEGLRVFGPNKKCAQLEGS
                     KAFSKEFMIKHNIPTAKYKEYTNLEEAISEIDSFGYPVVIKADGLAAGKGVVIPENRE
                     DAIATLKEMMSDKKFGAAGDKIVIEEFLKGIETSILAFVDNDTIVPMASAKDHKKVNN
                     YEQGPNTGGMGTFSPSEIYTEELANKVKETVLEKTLEGFKKDGLNFKGILFVGLMITE
                     DGEKVLEYNVRFGDPETQSVLFRLETDLHEIMEAILDNKLKDIEINYSDDEAVCVMLT
                     SGGYPDSYEKGKIITGLENLDDDIVVFHSGTKMFDGNLVTNGGRVIGITAKSTTVKDA
                     AEKVYENIKKINFEGMHYRTDIGR"
     gene            8348..12154
                     /locus_tag="PC494_001904"
     CDS             8348..12154
                     /locus_tag="PC494_001904"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase"
                     /protein_id="HDF3912405.1"
                     /translation="MLNTENKDSMVRRVLVEKREGFDLEAKALKKDLVESLHIDNIEN
                     LRILNRYDVEGISEEVYENAAKTIFSEPNLDVVYYEEIPKLNDERVFAIEFLPGQYDQ
                     RGDWAAQCVQIVNQGIRPAINTAKVYILSGKITDEEFSKIKDYCINPVDSREASLEKP
                     ETLKMETEIPTTVEVLDGFIDLDENGLRTFVSEKGLAMTLGDLQHVQKYFKDTEKRNP
                     TITEIKVLDTYWSDHCRHTTFMTEIENVKIEDGKFNDIVKEAYQMYLNSRDNVYVNRH
                     KDICLMDIATVAVKELKKNGKLNDLDESEEINACSINVDVEVDGKMEKYLVMFKNETH
                     NHPTEIEPFGGAATCLGGAIRDPLSGRSYVYQAMRVTGSADPRTTLEDTLPGKLMQRK
                     ITTEAAHGYSSYGNQIGLTTGQVAEVYDENFVAKRMEIGAVIAAAPKENVVRERPEAG
                     DVIVLLGGKTGRDGCGGATGSSKEHSEESILTCSAEVQKGDAPNERKIQRFFRNKEVA
                     QMIKRCNDFGAGGVCVAIGEIADSLDINLDLVPKKYDGLDGTELAISESQERMAVAIK
                     KENKDKFIQLAVEENLEATHVATVTDTGYLRMFWNGKAIVDINREFLDTNGVKQTTDV
                     HVTKVDEENTFFSSNEIVKDVKCASMKDKFTKVLSDLNVCSQKGLVEMFDNTIGGNTV
                     LMPFGGKYQATPTQGMVAKIPVLGGETNTSTIMTYGYNPKVGKWSPFHGALYAVVESV
                     CKLVAIGGNYSTTRLTFQEYFEKLGNNPEKWGKPFSALLGAFYAQSKFEIPAIGGKDS
                     MSGTFKDIEVPPTLVSFAVDTVDAKKVVSPEFKKADSKVVMLCVNKAENDVVDFEELK
                     RNLDKVRELIHGNKVLSTYALGFAGVGEAISKMAFGNKIGFKFSEEAEKAFTDDKLFE
                     ASYGNIVLELANDDLSMLEGYNYVVLGSTVKEASIFIKGEELALDELYKAHCSTLEPI
                     FPTKTEEVKSKIETISYISQGEAKKSSLSIATPRVFIPAFPGTNCEYDSARAFERAGA
                     NASIRVFKNLTYKDIEDSIDTIVNEIKSSQIIMLPGGFSAGDEPDGSGKFIATVFRNP
                     RVQEAINEFLTQKDGLMLGICNGFQVLIKLGLVPYGEIRVPSESAPTLTYNNIGRHQA
                     KIARTRISSNKSPWLAQTNVGDIHNIAISHGEGKFVASEDVMRELIANGQVATQYVDF
                     NNEATYDIEFNPNGSFYAVEGITSVDGRVFGKMGHSERIGEEVYKNIIGEKDQKIFES
                     GVKYFR"
     gene            12360..13232
                     /gene="rfbD"
                     /locus_tag="PC494_001905"
     CDS             12360..13232
                     /gene="rfbD"
                     /locus_tag="PC494_001905"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HDF3912406.1"
                     /translation="MKILITGSNGQLGKELVNQLEAINQSINQPKYVILATTRSDLDI
                     SNQTNVDNFILHNKPDVVVNCAAYTKVDACEDNIEIAYKINALGVRNLAIASEKVNAK
                     LIHISTDYVFNGFSKYPYREDNKTEPNSVYGKSKLMGEKFVEQFSHKYFILRTAWLYG
                     NGNNFVKTMIKLSLENTEVNVVNDQFGTPTSTVDLAKIIIKIMETEHYGVYHATCEGE
                     CSWYDFAKKIFKLKNIDIKVNPIKSNEFKCKAPRPLYSVLDNFMLKLIGLNSFRKWEE
                     SIEEYLERYDINEK"
     gene            13341..14210
                     /gene="rfbA"
                     /locus_tag="PC494_001906"
     CDS             13341..14210
                     /gene="rfbA"
                     /locus_tag="PC494_001906"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HDF3912407.1"
                     /translation="MKGIILAGGSGTRLYPITKCISKQTLPIYDKPMIYYPMSVLMLA
                     GIQDILIISTPRDIKAFEELFGDGSSLGLNITYAIQEKANGIAEAFIIGEEFIGNDRV
                     SLVLGDNIFYGYGFSERLENAVKRKGATIFGYHVSNPNSFGVVEFDKDFNVLSIEEKP
                     TVPKSNYAIPGLYFYDNDVVEIAKLVEPSDRGELEITSINSEYLKRGKLKVELLGRGM
                     AWLDTGTHKGLLDASNYVEVVQTRQGLYIACLEEIAYTKGYISREQLMKLAKPLIKTE
                     YGQYLLKLASEDM"
     gene            14259..14816
                     /gene="rfbC"
                     /locus_tag="PC494_001907"
     CDS             14259..14816
                     /gene="rfbC"
                     /locus_tag="PC494_001907"
                     /EC_number="5.1.3.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase"
                     /protein_id="HDF3912408.1"
                     /translation="MGKINVIKTKIEGLYIVEPNVFYDERGYFMESYNKKDFIEQGLD
                     MCFIQDNESSSRKGVLRGMHFQVKYPQGKLVRVTEGEVFDVAVDLRKDSQTFGKWEGV
                     ILSDKNKKQFYIPEGFAHGFLVLSEKAVFSYKCTNYYYPEFENGFIWNDKQISIEWPL
                     KGIEEIFLSEKDKKQKSFKDICTRR"
     gene            14854..15837
                     /gene="rfbB"
                     /locus_tag="PC494_001908"
     CDS             14854..15837
                     /gene="rfbB"
                     /locus_tag="PC494_001908"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HDF3912409.1"
                     /translation="MKKILITGGAGFIGSNFIHYMLNKYVDYFIVNLDLLTYAGNLET
                     LIEIQDNSNYKFVKGDISNREQVYKLFEEERFDIVVNFAAESHVDRSVENPDLFIKTN
                     IIGTQVLLDASIKYGVKRYHQISTDEVYGDLPIDRKDLFFTEQSSINPSSPYSASKAS
                     ADLLVSSYYRTYGLLTTISRCSNNYGPYHFPEKLIPLMILNALENKQLPVYGNGENVR
                     DWLHVYDHCTAIDLIIHKGNIGEIYNIGGHNERSNLEVVKMILNLLGKSEELISYVND
                     RPGHDLRYAIDATKIENELGWKAKYDFDLGIKETVKWYIENESWWKAVLSV"
     gene            15867..16535
                     /locus_tag="PC494_001909"
     CDS             15867..16535
                     /locus_tag="PC494_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic transglycosylase domain-containing
                     protein"
                     /protein_id="HDF3912410.1"
                     /translation="MNEISSLINILALTQLSGSNTTNQCNCTYNNSSGFDMIMMTLLK
                     ALSQNNQHTSNSYNLLSNSENLFNELDNVVNNTTSRFIDVDTKDKNVKLRIENAVDQA
                     SKKYNVDSNLIKAIIKVESDFNPNTVSSAGAKGLMQLMPENCRDLGVTDPFNIEQNID
                     AGTRHIKEYIDMFGGSIEMGLMAYNGGPGRMKSRGVESISDLYKMPKETQNYIPKVMK
                     YYRG"
     gene            16544..16972
                     /locus_tag="PC494_001910"
     CDS             16544..16972
                     /locus_tag="PC494_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YaaR family protein"
                     /protein_id="HDF3912411.1"
                     /translation="MGINIDKLNISPSINMEVKKLKESNKFSDKLNSLKQSSSLEDIK
                     RNLESVKKAGERLVLTQNYGDISIYKNAVKEYLKSVVDNMYSLDKNSSFWEHQYYKNV
                     KIVDSKLEDMTSKLISEEKENIDIVSTVDMIQGLLIDMYR"
     gene            16996..17310
                     /locus_tag="PC494_001911"
     CDS             16996..17310
                     /locus_tag="PC494_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FliM/FliN family flagellar motor switch protein"
                     /protein_id="HDF3912412.1"
                     /translation="MNSKKEDIYELNFGQLIEEKSGVIEENQNVFNAKVNVAVSIGNT
                     TETIKNILDLKEGSIIKLSKNVDEKLDIYANDRLFAYGESIITNERLSVRLSKIEDPD
                     VN"
     gene            17462..17737
                     /gene="flgM"
                     /locus_tag="PC494_001912"
     CDS             17462..17737
                     /gene="flgM"
                     /locus_tag="PC494_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis anti-sigma factor FlgM"
                     /protein_id="HDF3912413.1"
                     /translation="MDIKNVSSNIVVNNYLKNTSGIKKVEEVKKINKTDKIELSKFAK
                     EMASVSNMSDENIRNKKVDEIKNALENGTYKIKPKEIAKKMIEDMRG"
     gene            17742..18158
                     /locus_tag="PC494_001913"
     CDS             17742..18158
                     /locus_tag="PC494_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar protein FlgN"
                     /protein_id="HDF3912414.1"
                     /translation="MITDLKVIIYEEKNIISKMMELLKEQFDYIVEKDLENLNMLNPK
                     LEDISRELASIEIKRRQLFGDDISMSEVVENSNDGYLKEIYTDLKHILALAKNQQESN
                     DSLIKKELIFTKKMINFIKPADKQTTTYNSYGNIRK"
     gene            18176..19486
                     /gene="flgK"
                     /locus_tag="PC494_001914"
     CDS             18176..19486
                     /gene="flgK"
                     /locus_tag="PC494_001914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook-associated protein FlgK"
                     /protein_id="HDF3912415.1"
                     /translation="MAGLFSILNTANSGMNAHQKAIQTISHNISNLDTDGYSRQRTEF
                     ATNSPMYMPSLSNSIARGQLGTGVHVTDVTRARNSFYDYQFRAEAHKYGKTVSKYDYY
                     NTIETILNEPSDYGISAGIDDFFKGWESLSKDINSDSKKSLVVENASNLATLISESYK
                     KLDKLKEDIDSNIDTEIKQINDMLKSLEDLNKSIDIISGSGSTPNDLLDERDRILDNL
                     SFKLDFENSDVKNMLADGKLELNELKNPDGTWKTGISGTLQGLFEMHGKIDTYKSDLK
                     DVSDGLAKQINDVYNTSAGITVTDFFITSNVDGEDIIKINPAIKSNPNELKLTADEAS
                     KIAKLKDEKIDIGVAGGKVSTISDHYKAFAESIGLDSQKVNQDEANQRKIINNIDNSR
                     MSVSGVSLDEEMTELIKIQRSYQASAKVMSTAVQLLDVVINGII"
     gene            19505..20437
                     /gene="flgL"
                     /locus_tag="PC494_001915"
     CDS             19505..20437
                     /gene="flgL"
                     /locus_tag="PC494_001915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook-associated protein FlgL"
                     /protein_id="HDF3912416.1"
                     /translation="MRVSTGMMSSSYLNSLQDNLQRLDKVNRQVNTTKEINKLSDNPY
                     KAIKILNSKSEIKTMETYVENCKDTGNWLETTDTALDQLGKLLSDIKKTLVASGDGAY
                     SDDELKTLSNETNEKMKEIANALNATHEGKYIFSGSNTGVPPVECIDNADGSVSLKFN
                     SSLNLNKLNDSLSMDIAQGISVDYNVKLSSLGFDPTKTDPFEELNNISKKLANPDADA
                     IKELTTTCLGDMEQLIENTVNVRSIYGTKANTVEAMKEKNDDSLIQLKDILSQNEEID
                     YGEKLVQLKAAELTYQASLQTGGKLFNVSILDYI"
     gene            20453..20845
                     /locus_tag="PC494_001916"
     CDS             20453..20845
                     /locus_tag="PC494_001916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar assembly protein FliW"
                     /protein_id="HDF3912417.1"
                     /translation="MMKVTLKKGILGFENLKEYELLDIEDNDSLKEFNSTEEEGIGFV
                     VVSPFEIINEYEIVLNQETIEKLEVKSPKDVVLFNIITLGQTFEESTVNMKAPIVINI
                     KTNFGMQIILQDDKYSIRHPLLRGDNGC"
     gene            20839..21051
                     /gene="csrA"
                     /locus_tag="PC494_001917"
     CDS             20839..21051
                     /gene="csrA"
                     /locus_tag="PC494_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011987028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon storage regulator CsrA"
                     /protein_id="HDF3912418.1"
                     /translation="MLVISRKKDEAVLIGESIEVKIVGVDGNNVKLAISAPNNISILR
                     KEIYEKVKSENIKATNKNIKILKSLK"
     gene            21073..21468
                     /gene="fliS"
                     /locus_tag="PC494_001918"
     CDS             21073..21468
                     /gene="fliS"
                     /locus_tag="PC494_001918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar export chaperone FliS"
                     /protein_id="HDF3912419.1"
                     /translation="MYGENPYNSYKQNAVFMASKEQLLLMLVDGAVKYTKIARAAILD
                     KNTQKAHRELVRVQDIFTELMVTLDQNAGQWAKDMYKVYDFVRYELSRANIRKDIQVI
                     DSVLPVIEQIKDTWHEADKKSKEERSRDK"
     gene            21468..21824
                     /gene="fliS"
                     /locus_tag="PC494_001919"
     CDS             21468..21824
                     /gene="fliS"
                     /locus_tag="PC494_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar export chaperone FliS"
                     /protein_id="HDF3912420.1"
                     /translation="MELNLAELDKLSKEELLLMLVDGTVKYTNISKEALLNNDYLKAH
                     NELVRVQNIFTELMTTLDQNAGQWAKDMYKVYEFIKSELAIADENKDIKIIDDILPIV
                     KQIRDTWHEVYNQLKI"
     gene            21845..23368
                     /gene="fliD"
                     /locus_tag="PC494_001920"
     CDS             21845..23368
                     /gene="fliD"
                     /locus_tag="PC494_001920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar filament capping protein FliD"
                     /protein_id="HDF3912421.1"
                     /translation="MSSISPIRVTGLSGNFDMEGIIEASMIRDKEKVDKAKQEQQIVK
                     WKQEIYRNVIQESKDLYDKYLSVNSPNSIVSEKAYSSTRITSSDESIIVAKGSAGAEK
                     INYQFAVSQMAEPAKFTIKLNSNEPIVRQFPPNASGASSLTIGDVNIPISEQDTTSTI
                     VSKINSLCADNDIKATYSEMTGELIISRKQTGSSSDINLRVIGNDNLAQQIANDNGIT
                     FINDAGGNKVASVYGKNLEADVTDEHGRVTHISKEQNSFNIDNIDYNVNSKGTAKLTS
                     ITDTEEAVKNMQAFVDDYNKLMDKVYGLVTTKKPKDYPPLTDAQKEDMTTEEIEKWEK
                     KAKEGILRNDDELRGFVEDIQSAFFGDGKNIIALRKLGINESENYNKKGQISFNADTF
                     SKALIDDSDKVYKTLAGYSSNYDDKGMFEKLKDIVYEYSGSSTSKLPKKAGIEKTASA
                     SENVYSKQIAEQERNISRLVEKMNDKEKRLYAKYSALESLLNQYSSQMNYFSQAQGN"
     gene            23371..23706
                     /gene="fliT"
                     /locus_tag="PC494_001921"
     CDS             23371..23706
                     /gene="fliT"
                     /locus_tag="PC494_001921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar protein FliT"
                     /protein_id="HDF3912422.1"
                     /translation="MDKLKEKLNLYKDISLQIINLIEKEEYIKISIKLGERQEIINSV
                     SEIDRNDFIQLYNRMELIEIDSRIRDILQGQLLEVKKELHEYKLTKQVNTMYYNLNRE
                     KVNIFNKKV"
     gene            23808..24680
                     /locus_tag="PC494_001922"
     CDS             23808..24680
                     /locus_tag="PC494_001922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellin"
                     /protein_id="HDF3912423.1"
                     /translation="MRVNTNVSALIANNQMGRNVNAQSKSMEKLSSGVRIKRAADDAA
                     GLAISEKMRAQIKGLDQAGRNVQDGISVVQTAEGALEETGNILQRMRTLSVQSSNETN
                     TAEERQKIADELLQLKDEVERISSSIEFNGKKLLDGSSTEIRLQVGANFGTNVAGTSN
                     NNNEIKVALVNTSSIMSKAGITSSTIASLNADGTSGTNAAKQMVSSLDVALKELNTSR
                     AKLGAQQNRLESTQNNLNNTIENVTAAESRIRDTDVASEMVNLSKMNILVQASQSMLA
                     QANQQPQGVLQLLG"
     gene            24773..26914
                     /locus_tag="PC494_001923"
     CDS             24773..26914
                     /locus_tag="PC494_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HDF3912424.1"
                     /translation="MLLSIVMIVKNEEKILEKTLKSLTTLRNSIESELIIVDTGSTDD
                     TIKISKKYTEKVYFHNWNNDFSSMRNISISYAKGEWLLILDADEILIDSSTIVKFFKD
                     GLDKKFNSASIQLKNLYSYDKKLYGYCSVLRLFKNVDFRYHGKVHEQPIYKNPIFNNV
                     ADFEHYGYLFEDEEIRLNKVKRNEKLLFQELKENDNSPYTNYQLGKNFIILGKYQEAL
                     YYLEKSYELYSKLELAPGYLITSLVKTYLYLGKHKKCERLCLKYIKKDMNNIDIYYYI
                     AQAQVDLGKYENSIDSYKRYIYLLDNYEISTQANSLFSDTDTVGLRDEAIITLIKIYY
                     KLEKYEFVISEYNNIEDVEKKKNVYFSLFMSLYKLNRFEDIKNYYKEVSNSKIEKNSF
                     YRNIEEVINNIKEDEKEYVYKILCDIEGNYGILNQIRINKCVSIDKCKEILNEEKEII
                     YAYIIKIAFEEKIDLLDIFYEMEYVWIEKYLKYLLALERSFNLVLYKYIISRPNTSDM
                     EKIRVYKAISKVVLESISLSDEKYKEIFYFYIMYSYKYIRYIYSNLSDFELKKFVCND
                     LDKFTIEFKHLLDIKNKVNNANEKLEYIHSMRKLLNEYPFYNKIIKILIGELEENIKE
                     SEEFKDLKYSFIISIENMIETGKINDAKLLVDDYSKTFVDDVRILNIKGILYMFENKL
                     DKADFMLKKALSLDVENEDTIYNIEYLKSLR"
     gene            26938..28815
                     /locus_tag="PC494_001924"
     CDS             26938..28815
                     /locus_tag="PC494_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HDF3912425.1"
                     /translation="MNIPIVVNEKSKDIIKDWQYTCTNEDIKFTSIIILTYNQIEYTK
                     LCIESIRKFTPKNKYEIIIIDNNSSDGTVEWLKGQSDIKSVYNNKNLGFPKGCNQGIE
                     LATGENILLLNNDVIVTPNWLYNLNKALWSQDNIGAVGPITNACSYYQQIDVDYKSIE
                     DMFIFAHKINKSNINLWKYRLKLVGFCMLIKKTVLDNVGVLDELFTPGNFEDDDLSFR
                     MIESGYKLLLCQDTFIHHFGSVSFKENRNKYTDIMYINRRKFETKWGFNPEYSGMIRT
                     DLISKIDDSLEANINVLEIGCGIGATLLEIKNIYKNASIYGIEISESAGKLAKYSADV
                     LIANIEKVKLDYKKDFFDYIILGDVLEHLIDPWKIVNELKQYLKKDGYLVSSIPNIMH
                     VSVLRNLVLGNFTYEDSGILDKTHLRFFTLNEITKMFNDSNYIINSITATSMPLSEID
                     NSFIDTICKESCKEMRQQYESYQYIVKASKILDTKRYSSISMINLKYALMRIDNELDV
                     DSNLSYIFDNYNITEPCFVDDIEYLIDTFVINKATLLNRLGVEAFNRGLGDFSINMFM
                     TVLEMDRDDIDSIYNITSVLCELEEFDTAYNLIKNSSEKVQSESDIQEILCFIEGKKY
                     E"
     gene            28808..30922
                     /locus_tag="PC494_001925"
     CDS             28808..30922
                     /locus_tag="PC494_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HDF3912426.1"
                     /translation="MNNDKICFITCVNDERLYEECLVYINSLDIPKNFSIETVALRGA
                     DSIASAYNKAMRETDSKYKVYLHQDTFIINKNFIHDILEIFKKNTDVGMIGVAGVKDM
                     PVNGIWWDSDKKAGKVYDSHTGKMDIYEFSNFEECFNEVMAIDGLIMITQYDVFWRED
                     KFDGWHFYDLSQSMEFRQNKYKVIVPKQNKPWCMHDSGVVNINNGYDEYRIKFVKEYI
                     NLDLYRENFYEFDKKKASTILKSNKHVMDCMKEELTEQLRLKNYKDVLGIVSKIAHFS
                     VFNHTGLYSCEECERALLECANNLPEIENTKLFTKKDLKRRKVLHVLSEGYSTGGHTR
                     LVKNWIEIDKDSVHSVVTTWQSDTLPDWLLKAINDSGGEVISLDLISDDYLKRAVALR
                     KIAYDWADIVILYVHMWDTIPVVAFGVDGKIPILHVNHYDSTFWLGTSIADIVIDFSE
                     TSQLITLDKRGIDKSEILPMPLKEKEVFSKSEVRKRYNLEDDVTIILTIASERKYNSV
                     NDINYFKIAKTLIENTDNTIIIVVGVDTENLYWKTLSNVTDNRVICFGTTANIDDFYK
                     ISDIYLESFMVGSHTSKLDAILYDLIPVKFKNEVSPIFTNMWNFIDKFDYKNIKEVID
                     MIRRYNTSEFDRDKIKAKQSEIKHFVIDKHCIEIKNYIDKIYNEVNHHKVKYDLYKND
                     EIEDYQLFVALYGYMVKNKNMS"
     gene            30931..31926
                     /locus_tag="PC494_001926"
     CDS             30931..31926
                     /locus_tag="PC494_001926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation glycyltransferase
                     FemA/FemB family protein"
                     /protein_id="HDF3912427.1"
                     /translation="MNNIHINKFEKSCEKNWDYFVENKSINGTFLQTRNFLNYHEEGK
                     FTDHSLIICKGEEILAVVPACETYEDGERIFFSHLGSTFGGIIIRSGFNDIRHVNAIT
                     NKLEIYLQEQNFDKVYLKNTSRIFCKEDTSLLEYFLFKNNYMFYDELSMFLELSKYKE
                     DILANFKYSKRRDFKYSLKNNLTFKRLYSDEDIVCFFNLLSNCLDSKGAKVIHSVEEL
                     LEFKNNRLKDIVEFYAVYIDDIMICGSMVFNFQERVYHTQYLASNSTYNKYYPMIFLY
                     YNLIKDALERNFKYLSFGISTLNRGKYLDEGLATFKEGFGSSAICNRTYYKNINK"
     gene            32018..33250
                     /locus_tag="PC494_001927"
     CDS             32018..33250
                     /locus_tag="PC494_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HDF3912428.1"
                     /translation="MKRLMILGSIKYFENIVMSAKREGIYTIVCDNRIDTPAKKICDE
                     AIDVDVFDFDKIKNIAIDKKIDGILTGFTDSLMKPYVYIANELNLPCVISCNQLESVT
                     NKAVMKNYFKNNGIPTTDYCIIESLKDLEKIQGLNFPLVIKPVDGYGSRGVYFVSNIE
                     ELIEKFEYSKEASQDGQVIIEEFYESEEIQGLAWVHNGESHVFYIGDRELVNIHTGRA
                     GKPDRLIYPSKYCFQYEEEIKSIYQNITQAFGIKNGPLYVQMLVGAYGIKVSEVMPRL
                     PGGCDYMAISQITDLDIGSLFANFSVNNEVNFDEIKKYNMHLSKCVYALPIYIRPGTI
                     KKINNIDKIENLDYVTQFLLLVKEGDTIGLYEDERQDCGRVYGVANNVFDANIKKKCI
                     HEMIEILDENNENMIENF"
     gene            33270..34214
                     /locus_tag="PC494_001928"
     CDS             33270..34214
                     /locus_tag="PC494_001928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine cyclodeaminase"
                     /protein_id="HDF3912429.1"
                     /translation="MKLITHEQIMSLNISQKQGYEWIKESFLTKKDCQLPPKISMVEE
                     GHVFYNVMPSLNHNHKIGGIKMVTRLPGRNPSLNSEIFLYNMEDAKLKAILDGNYITA
                     FRTAAVAALAIDTFAKKDFNTIAIMGLGVTASAIMNMLSYTLKDKNINIKLLKYKDQA
                     ESFVKKYEKNEQFSFEICDTHEELIVDSDVVISTVTYTDEYLSEFKWFKKGALLLPVH
                     VMGFGNVDYLFDKVYLDDYNHLKHLENIDRYKYSCEFYDVLSKQAKGRENDDERIISY
                     NIGLSIHDILFANKIYELCETLSCEEIELKEPKEKYWI"
     gene            34308..34715
                     /locus_tag="PC494_001929"
     CDS             34308..34715
                     /locus_tag="PC494_001929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxcM-like domain-containing protein"
                     /protein_id="HDF3912430.1"
                     /translation="MDKYNLIRFVSIGNEYIGNLVALESNKAIPFDIKRVYYIYDVPN
                     NVKRGFHAHKNLEQVLVCLNGSVKIKCYDGVKETIFNLHKNDVGLYIGTGVWHEMFDF
                     DEKTVLISIASEHYNEEDYIRDYKEFLKYLNNV"
     gene            34802..>35889
                     /locus_tag="PC494_001930"
     CDS             34802..>35889
                     /locus_tag="PC494_001930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegT/DnrJ/EryC1/StrS family aminotransferase"
                     /protein_id="HDF3912431.1"
                     /translation="MLVKFNNLLKQFQTHKEEYEQKIKDVMESGYYILGNEVKHFEEE
                     FANYVGSKYCVGLASGLDALIIAFRALGISKGDEVIVQSNTYIASVMGISINGATPVF
                     VEPNEYYNIDSSKIEEKINSKTKAILVVHLYGQASNMKDIQELCDKYNLYLIEDCAQS
                     HGAKYDGKMTGTFGDIGCFSFYPSKNLGAFGDAGAIVTSNEEIADKVKILRNYGSEKR
                     YYNKFVGYNSRLDEIQAGLLRVKLKYLNEIEIEKSKIVDRYLNEINNPKVILPKIENN
                     CTHVWHLFVLQVEKRDTFMEYLKKSGIESIIHYPIPPHLSEAYAYLGYKKGSFNIAEN
                     YSDKVVSIPLFIGMEDEEVSYIIKIINE"
BASE COUNT        14677 a         3617 c         6568 g        11027 t
ORIGIN      
        1 ggtagtagtg gcgaagacac cgtccgaagt agcttggctt tgtaaccacc tctgttgtac
       61 tgtttaagta taaataagtg tgttagccac caagaatccc cttgctttag ctatggggag
      121 tgtgtcaata aaatacttta atgaaaaata gctaacttta attgtaggat attcttaata
      181 tatttgaaat aaataaaaat attgaaggat ataatattca attggtatat aaataataaa
      241 tgatagttaa attttacctt agaggctaat taggtgttta atcaaagtta atgcctttag
      301 aatacaaatg tattctaaag gcatttttac tatgtatttt catttatatt actaaacatt
      361 atctattttt atatacattt ctatgtattt tattttcatc aaatcggtct ataaactcat
      421 ttttttcttc actatatcca atagatataa gtgcataagg aactaatttt actggtaagt
      481 ctaaagtttg tctaacttta tttaccactt tatttttagg aaatactcct gcccaacaag
      541 cagctagacc ttgattagta acttctaata ataaattttg tgtgcaagca cctaaatctt
      601 gtatccattt accaggtttt aagaatttat ctctatttcc aagcactact atacataatg
      661 gtgcaaattc tatatgcttt gctctatgct gtgactttga gagctgtttc agcagttcct
      721 tatcatctac tataataaat tcccaaggtt gagcattttt tgatgaaggt gcttgcatag
      781 ctgattttag tatttcagtt attttatctt cttctatatt tttatctata tatgttctta
      841 ttgaatgtct attttttata acttctaaca tacagattct cctttaaata aaattatttc
      901 tatttatata atatcattac tttaaatttt agctattact tatataaaga ataaactttg
      961 tgttggtttt atctaagtaa aagtaacatt cagaactaaa aaacaagact ataaatccaa
     1021 agtattaatt aaaaaagaag taataaaaaa taatatacaa gatttaaaaa agagtattgg
     1081 gcttaaaatt taattagaaa accaattttg agataatctg ttttttattt taacaaaaaa
     1141 acataaataa agttcgatac atagcgaatg aaaaaattac aagaaatatt ttttttaaaa
     1201 aatttcaaaa aagagttgat aatatatgta tattaatata aaatttaagg tgtataattc
     1261 gtataataat acgaatgatt tgtagtgtaa aataacttat aaacggagag gggaagtcta
     1321 atgaaagtag cagtagttat gggttcaaaa tcagattatc caaaattaga agaagggata
     1381 aaactgcttg aaaaatatgg aatagaagtt gtagcaagag cattatcagc tcatagaaca
     1441 ccagaacaac tttcaatatt cctaaaagaa atagaagatg atactgatgt aataatagca
     1501 gcagcaggaa aagcagcaca cttaccaggt gtaatagctt cacaaacatt aattcctgta
     1561 ataggattac ctattaaatc atcaactatg gatggactag actcactttt atcaatagtt
     1621 caaatgccaa aaggaatccc agttgcaaca gttacaatag acttaggttt aaacgcagct
     1681 ttattggcat tacaaataat gactttaaaa tacccaaaat taaaagagga tttgaaatca
     1741 tatagagaag agatggcaca aaaggtgtta gaagacgaca agaatttaag ggggtagcag
     1801 aaatgttatt atatgaagga aaagcaaaac aagtatattc tacagataat gaaaatgaat
     1861 atgttgttta ttataaagat gatgcaacag catttaatgg agaaaaaaaa gcagaaatat
     1921 cttcaaaagg tatactaaat aataagatat caacaataat ctttgaaatg ttaaaagaaa
     1981 ataatataaa tactcacttt ataaaaagtt tatcagatag agaaatgtta gttaaaaaag
     2041 tagagatttt accattagaa gtaatagtaa gaaatattgc tgctggttct atctgtaaaa
     2101 gagttggtct tgaagaaggt gtagttttcg atgagccaat ttttgaaata agctacaaaa
     2161 atgatgctta tggtgaccca atgctaaatg atgattatgc agtggcaatg aagttagcaa
     2221 ctagagaaga gttaaaattc ttaagagaag aaactttaaa aataaacgag ttactaaaag
     2281 catttttctt aaaattaaac ctaaagttag ttgactttaa aatagaattt ggtaaagatt
     2341 ctgaaggaaa tataatattg gcagatgaag tatcaccaga cacttgtaga ctttgggatg
     2401 taaatacaaa tgaaaagtta gataaggaca gatttagaaa agaccttgga gaccttgtag
     2461 aaggttatac ggaagtactt tcaagaatga ataataaata ggaggcaaat gtatgtgtgg
     2521 agttttaggg atttactcta ataaagatgt aactaaagaa ctatattatt ctttatattc
     2581 tatgcaacac agggggcaag aaagctgtgg tttagctctt ttagatgatg gagaaattaa
     2641 gtacaaaaaa gatatgggat tagttggaga tgtttttaag gaaaatgaat tatctaagtt
     2701 aaaaggaaat atagggattg gacatgttag atattcaaca gctggaggaa gtcatgtttc
     2761 taactgtcaa cctttagttg gaagttgtag aaaaagacaa ttagccatag ctcataatgg
     2821 aaatctagtt aatgcaaatt atttaaaaga tatgctagaa gaagatggat atatgttcca
     2881 aactaattca gatacagaag tgattttata tatacttgct agatattaca aaggggatat
     2941 agtagaaagt ttaaaagtga caatggatta tataaaaggt gcatatgctc ttgtaataat
     3001 gagtcaagaa gaattggttg cagttagaga cccacatgga ttcagacctc ttgtacttgg
     3061 taaaaagggt gatgaatata tatttgcatc agaaaattgt gcaatagata tacttggcgg
     3121 agaagttata agagatgtag agccaggaga gataatagta gtcaaagatg gagaactaaa
     3181 atcatatttt tattcagaaa attataaacc agttaagaaa agttgtatat ttgaacacat
     3241 atactttgca agaaatgatg caactataga caatgtaaat gcatatgaat ttagaattaa
     3301 atgtggtgag agattagctc agaatgaaac tgtaaaggca gatatggtag ttccagttcc
     3361 agattcaggt tggccaggag ctattggtta tgcaaatgct agtggattaa aaataagtga
     3421 aggcttagtt aaaaatagat atgtaggaag aacatttata aaacctacac aagaagaaag
     3481 agaaatagca gtaaaaataa aattaaatcc tctttcaaca ataataaaag gaaaatctat
     3541 aattttagta gacgactcaa ttgtaagagg aactacatct aaacaattag taaaatcttt
     3601 aagagaagca ggagcaaaag aaattcatct tagaataact tctcctccag tagcttactc
     3661 ttgttactat ggaatagata ctccaaatcg ctctaaatta attgcatcaa gtaacaacgt
     3721 agaagaaatg agagaatata ttggatgtga tagtttaaaa ttcctagata tagaaggaat
     3781 gttagatgca acagaacata agtctacttt ctgtaaagct tgttttgatg gagaataccc
     3841 agttaagaaa attgataagg aggaactact ttcatgttaa catataaaga atcaggtgta
     3901 gatatagatg aaggaaatag agcagtagac cttataaaag gtaaaataaa aggaacttat
     3961 gatggaaatg tagttggaga tttaggtaac ttcagtggat tatacagttt aaaagatttt
     4021 gtaggtatga aagaaccagt tttgcttgca tctacagatg gtgttgggac taagttaaaa
     4081 atagctcaga tgatggacaa gcatgatact gttggaatag atttagttgc aatgtgcgtg
     4141 aatgatttaa tttgtcaagg agcaaaacca ttattcttcc ttgactatat agctcttggg
     4201 aaattagtgc ctgagcatat cgaaaaaata gttggtggaa ttgcagatgg ttgtaaaatg
     4261 tctggttgtg cactaattgg tggagaaact gctgaaatgc ctggaatgta tggagaagat
     4321 gactatgatt tagcaggatt ttctgtagga atagcagaca aagaaaagat tgtttctgga
     4381 aacaatgtta aatcaggaga tgtattggtt ggtatatctt caagtggagt acacagcaat
     4441 ggattttctt ttataagaaa gatattttta gaaacttaca attataaaat ggaacaatat
     4501 gttgaagaac taggaatgac agttggagaa gcacttttaa caccaactaa aatatatgtt
     4561 aaattagctt tagatgtatt agctaaacat gacataaaag ctatagctca cataactggt
     4621 ggagggctta tagaaaatat aacaagagtt atacctaaag ggttaggact agatatcaat
     4681 aaaaaatctt gggagaagcc tcctatattt aaaatgatag aaggttttaa tgctgttgat
     4741 gagagagaac ttcataagag ttttaacatg ggtattgggc tagttttaat agtagataaa
     4801 gaaaatgctg atgatgttgt aaactttata aataatagag aaaatgacaa tgctgcttat
     4861 gtagataaaa aatatagtga attattagaa gataaagctt atataattgg tgaagtagta
     4921 gatagtcatg aaggtgtaga attatgctaa atataggagt tttaatatct ggtggaggaa
     4981 caaatttaca agcagttata gatggtactg agtctggaga aataaaaggt caggttaaag
     5041 tagttatctc aagtaagcaa ggtgcttatg ggctagagag agctaaaaat cataacataa
     5101 aagcaatttg tgaaactgat gaagacaaga taatagaaat tcttaaggaa aataaaatag
     5161 atttagtagt tttggctggt tatttaaaaa taatcagccc aaagctggtt aacgagttta
     5221 gaaacaaaat gataaacata catccatcat taattccttc attttgtgga gctggattct
     5281 atggagaaaa agttcatcaa ggtgttatag attatggagc taaagtaact ggtgctacag
     5341 ttcattttgt agatgaaggt gctgatactg gaccaatcat aatgcaagat gtagttaagg
     5401 taaatcaaga tgatgatgca aagacacttg caaaaagagt gttagaagtt gaacatagga
     5461 ttttaaaaga aagtataagt cttttttgtg aaaataaatt aaaacttcaa ggtaggagag
     5521 tgtttataaa tgagtaagag agctttaata agtgtaactg acaagactgg tgtagtggaa
     5581 tttgctaaag agttaaataa attagattat gaaattatat ctacaggaaa tacatttaaa
     5641 acattaaaag aaaatggtgt taatgtaatg caagttgaag atgttacaaa ttttccagaa
     5701 atattagatg gaagagtaaa aacattaaat ccatatatac atggtggtat actttataaa
     5761 agagataaag aatctcatgt agaaactgta aatgaacaca aaatacattc aatagattta
     5821 gtagctgtaa atctatatga ttttgaagga actttaaaag ctggaaaaag tcatgatgaa
     5881 ataattgaaa atatagatat tggtggacca tctatgatac gttctgctgc caaaaactat
     5941 aaggatgtaa tagtagtagt agatataaaa gattatgatt ctataataga aaaattaaaa
     6001 acagatacaa tgacattaga agacagaaaa aaattatcat ataaagcttt ctcaactaca
     6061 ggaagatatg atgcgttaat atctagttat tttgctggag aagttggaga tacgtatcct
     6121 gacatattaa atttaacttt ccaaaaagaa caaactttaa gatatggaga aaatccacat
     6181 caaaatggtt tcttatattc acagtcaaat gcaaaaaatc caatcttaaa ttatgagcaa
     6241 ttaggcggta aagaactttc ttttaacaac ttaaatgatt tacatggatg tttagaagta
     6301 atgagagaat ttaaagatag tgaagaagta gtttcagtag ctataaaaca tgctaattca
     6361 tgtggggtag gtttaggaaa agatgctttt gaagcatata caaaatgtta tgaagcggat
     6421 aaggtttcaa tatttggagg aatagtagga ataacttcta ctatagataa agctacagca
     6481 gagaaattaa atgaaatatt cttagaaata gtagtagcat atgattttga accagaagct
     6541 ttagagatac ttaaacaaaa gaaaaatcta agaatattaa aattagctaa aatagaaaat
     6601 agtttacaac catatgaaat gaaatattta gatggaaaat tattgataca agatagaaac
     6661 aatatattag cagaaaaaag tgaaaatgta acaaaggaaa aaccaacaga tgcacaactt
     6721 aaggacatgg aatttggtat gagagtagta aaaaatatga aatcaaatgc aattgcaata
     6781 gtaaaaaatg gacaaactct agctttaggt tgtggacaaa catcaagaat ttgggcatta
     6841 aaaaatgctc ttgaaaataa caaagataaa gattttacag gagctgtttt agcgtcagac
     6901 gcatttttcc catttgatga ttgtgtaaca ttagctcatg aatatggaat atcagcagta
     6961 gttcaaccag gtggctctat aaaagataaa gattcaatag aagcttgtga caagtatgat
     7021 atggttatgg tatttacagg aataagacac ttcaaacact aaggaggata ttatgaagat
     7081 attggttgta ggcggtggcg gaagagagca tgctatatgc tggaaactaa gcaaagaaaa
     7141 aaatgtagaa aaaatttatt gtgcaccagg taatgcagga attgcaaacg tagcagaatg
     7201 tgtaaatata ggtgatacta atatagaaga acttttaaaa tttgccaaag aaaatgaaat
     7261 aggtctgaca atagtaggac cagaagtacc actagttatg ggaatagtag atgagtttga
     7321 aaaagaagga ttaagagtat ttggacctaa taaaaaatgt gctcaacttg aaggaagtaa
     7381 agctttttca aaagaattta tgataaaaca taacatacct actgcaaaat ataaagaata
     7441 tacaaactta gaagaagcta tatcagaaat agatagtttt ggatatccag tagtaataaa
     7501 agcggacgga ttagctgctg gaaaaggtgt tgtaatacct gaaaatagag aagatgctat
     7561 agcaacttta aaagaaatga tgtcagataa gaagtttgga gctgctggag ataaaatagt
     7621 aattgaagag tttttaaaag gaatagaaac ttcaattcta gcatttgtag acaatgatac
     7681 aatagttcct atggcaagtg caaaagacca taaaaaagta aacaactatg agcaaggtcc
     7741 aaacactggg ggaatgggaa ctttttcacc tagtgaaata tatacagaag aattagcaaa
     7801 taaagtaaaa gagacagtat tagaaaaaac tttagaaggc ttcaaaaaag atggacttaa
     7861 ttttaaaggt attttatttg ttggtcttat gataactgaa gatggagaaa aagtacttga
     7921 atataatgta agatttggag accctgagac acaatctgtt ttatttagat tagaaacaga
     7981 tttacatgag ataatggaag ctatactaga taataagtta aaagatatag aaataaacta
     8041 tagtgatgat gaagctgtgt gtgttatgct tacatcagga gggtatccag acagttatga
     8101 aaaagggaaa attataactg gtcttgaaaa cttggatgat gatatagtag tattccatag
     8161 tggcactaag atgtttgatg gtaatttggt taccaatgga ggaagagtaa ttggtataac
     8221 tgcaaagtca actacagtta aggatgcagc agaaaaagtt tatgaaaaca taaagaagat
     8281 aaactttgaa ggaatgcact atagaacaga cataggaaga taatttttct aaaatggagg
     8341 ataaggtatg ttgaatactg aaaataaaga ctcaatggtt agaagagtat tggttgaaaa
     8401 aagagaaggt tttgaccttg aggctaaagc tttaaaaaaa gacttagtag aaagtttaca
     8461 catagataat atagaaaatt taagaatatt aaatagatat gatgtagaag gaatatcaga
     8521 agaagtttat gaaaatgcag caaagacaat attctctgaa ccaaatttag atgtggtata
     8581 ttatgaagaa ataccaaaat taaatgatga aagagtattt gcaatagaat ttcttcctgg
     8641 tcaatacgac caaagaggtg attgggcagc tcaatgtgta caaattgtaa atcaagggat
     8701 aagacctgct attaatacag caaaagttta tatattatca ggcaaaataa ctgatgaaga
     8761 gttttctaaa ataaaagatt actgtataaa tccagtagat agtagagaag catctttaga
     8821 gaaaccagaa acgttaaaaa tggaaactga aataccaaca acagttgaag tattagatgg
     8881 atttatagat ttagatgaaa atggattaag aacatttgta agtgaaaaag gattagcaat
     8941 gactttagga gacttacaac acgttcaaaa atactttaaa gatacagaaa agagaaatcc
     9001 aactataaca gaaataaaag tattagatac ttattggtct gatcattgta gacatactac
     9061 ttttatgact gaaatagaaa atgtaaagat agaagatggt aagtttaatg atatagtaaa
     9121 agaagcgtat caaatgtatc ttaactcaag agacaatgta tatgtgaaca gacataaaga
     9181 tatatgttta atggatatag ccactgttgc agtaaaagaa ttaaagaaaa atgggaaatt
     9241 aaatgaccta gatgaaagtg aagaaataaa tgcatgtagt ataaacgtag atgttgaagt
     9301 tgatggtaag atggaaaaat atctagtaat gtttaaaaat gaaactcaca accatccaac
     9361 tgaaatagaa ccatttggtg gagcagctac ttgtttaggt ggagctataa gagacccatt
     9421 atcaggaaga agttatgttt atcaagcaat gcgtgttaca ggaagtgctg acccaagaac
     9481 gactttagaa gatactttac ctggaaaact tatgcaaaga aaaataacta cagaagctgc
     9541 tcatggatat agttcatatg gtaaccaaat aggtcttaca actgggcaag ttgcagaagt
     9601 atatgatgaa aactttgttg caaagagaat ggaaataggt gcagttatag cagcagcacc
     9661 aaaagagaat gtagtaagag aaagacctga agcaggagat gtaatcgttc ttcttggagg
     9721 aaaaacagga agagatggct gtggaggagc aactggttca tctaaagaac atagtgaaga
     9781 gtcaatctta acttgtagtg cagaagttca aaaaggagat gctcctaatg aaagaaaaat
     9841 acaaagattc tttagaaata aagaagttgc tcaaatgata aaaagatgta atgattttgg
     9901 agcaggtgga gtttgtgttg ctataggaga gattgctgat agcttagata taaacttaga
     9961 cttagttcct aaaaaatatg atggacttga tggaactgag cttgcaattt cagagtcaca
    10021 agagcgtatg gcagtagcca taaaaaaaga aaataaagat aaatttatac aattagcagt
    10081 agaagaaaac ttagaagcta cgcatgtagc tacagtaaca gatacaggat atttaagaat
    10141 gttctggaat ggaaaagcaa ttgtagatat aaatagagag tttttagata caaacggagt
    10201 aaaacaaact actgatgttc atgttactaa agtagatgaa gaaaatacat tctttagctc
    10261 taatgaaata gtaaaagatg ttaagtgtgc aagtatgaaa gacaagttta caaaagtact
    10321 atctgacctt aatgtttgtt ctcaaaaagg attagtggag atgtttgata atacaattgg
    10381 tggtaataca gtacttatgc catttggagg aaagtatcaa gcgactccaa cacaaggtat
    10441 ggttgctaag ataccagtac ttggaggaga gactaatact tctacaataa tgacttatgg
    10501 atacaatcca aaggtaggaa aatggagccc attccatggt gccttgtatg cagtagtaga
    10561 atctgtgtgt aaattggttg ctattggagg aaattatagt acaacaagac ttacattcca
    10621 agagtatttt gaaaaacttg gtaacaatcc agaaaaatgg ggtaaaccat tctcagcact
    10681 tttaggagca ttttatgcac aaagtaaatt tgagatacct gctataggtg gaaaagacag
    10741 tatgtctggt acatttaaag atattgaagt tccaccaaca ttggtttcat ttgctgttga
    10801 cacagtagat gcgaagaaag tagtatctcc agaatttaaa aaagcagact caaaagtagt
    10861 aatgttatgt gtaaacaagg cagaaaatga tgttgtagat tttgaggaat taaagagaaa
    10921 cttagataaa gtaagagaac ttatacatgg aaataaagtt ttatcaacat atgcattagg
    10981 atttgcaggt gtaggtgaag caataagtaa aatggctttt ggtaataaaa taggatttaa
    11041 gtttagtgaa gaggctgaaa aagcatttac agatgataaa ttatttgagg ctagttatgg
    11101 aaatatagta cttgaattag caaatgatga tttaagtatg ttagaaggat acaattatgt
    11161 tgtgcttgga agtacagtta aagaagctag tatatttatc aaaggtgaag aacttgcatt
    11221 agatgaatta tataaagcac attgtagtac tttagagcct atattcccaa ctaaaacaga
    11281 agaagtaaaa tcaaagatag aaactataag ttatatatca caaggagaag ctaaaaaatc
    11341 atcattaagt atagctactc caagagtatt tataccagca ttccctggaa caaactgtga
    11401 atatgactct gcaagagcat ttgaaagagc aggagctaat gcaagtataa gagtatttaa
    11461 gaatttaact tataaagaca tagaagattc tatagataca atagtaaacg aaataaaatc
    11521 ttctcaaata ataatgttac caggtggatt tagtgctggt gatgagccag atggttctgg
    11581 taaatttata gctactgtat ttagaaatcc tagagtgcaa gaagctataa atgaattttt
    11641 aactcaaaaa gatggactaa tgttaggtat ctgtaatgga ttccaagtat taattaaatt
    11701 agggttagtt ccatatggag aaataagagt tccaagtgaa agtgctccaa cacttactta
    11761 caataatatt ggtcgccatc aagctaagat tgctagaact agaatttcat ctaataaatc
    11821 tccttggtta gctcaaacta atgttggaga tattcataat atagcaattt ctcatggaga
    11881 aggtaagttt gttgccagtg aagatgttat gagagaatta attgctaatg gacaagtagc
    11941 aactcaatat gttgacttta ataatgaagc tacttatgat attgagttta atccaaatgg
    12001 ttcattctat gctgttgaag gtataactag tgttgatggt agagtgtttg gtaaaatggg
    12061 acattctgaa agaattggtg aggaagtata taagaatatt ataggtgaaa aagaccaaaa
    12121 gatatttgaa tctggagtta aatattttag ataaagcttt gatgtttaat tgatagctag
    12181 aatatataat ttagatattt agatttaaag agatgtaata atatgatgat aatcatttaa
    12241 tattacatct cttttttatt tatctaagaa ataataagtt caacctaagt taaaatacaa
    12301 gctgtgttat aattaattat taagtaaaat tgaatattta ttggagggca acataattaa
    12361 tgaaaatatt aataacaggg tctaatggtc aattaggaaa agaattggtt aaccaattag
    12421 aagcaatcaa tcaaagtata aaccaaccaa aatatgttat attagctaca acaagaagtg
    12481 atttggacat atccaatcag actaatgtag ataattttat tttgcataat aaacctgatg
    12541 tagttgtaaa ctgtgcagca tatacaaagg ttgatgcatg tgaagataat atcgaaattg
    12601 catacaaaat aaatgcttta ggagtgagaa atctagcaat agcatcagaa aaagttaatg
    12661 ctaagcttat tcacatatca actgactatg tattcaatgg tttttctaaa tatccatata
    12721 gggaagacaa taaaactgaa cccaattctg tatatggaaa aagtaaactt atgggagaaa
    12781 aatttgttga acaattctca cataagtact ttatattgag aacagcatgg ttatatggta
    12841 atgggaataa ttttgtaaag accatgataa aactttcttt agaaaataca gaggttaatg
    12901 tggttaatga ccagtttgga actccaacaa gtacagtaga cttagcaaaa attataataa
    12961 aaatcatgga aacagaacat tatggagttt atcatgctac atgtgaaggt gagtgtagtt
    13021 ggtatgattt tgccaaaaag atatttaaac taaaaaatat agatataaaa gtaaatccaa
    13081 ttaagagtaa cgaatttaaa tgtaaggctc caagaccact atattctgta ttggataatt
    13141 ttatgttgaa gttaattggt ttaaattctt ttagaaagtg ggaagaatcc attgaagaat
    13201 atttagaaag atatgatata aatgaaaagt aaatgtatta ttttgagaaa agaaaataag
    13261 atattataaa aaatataaat atttctttta tttatccgat aatcataata tgacaaaaac
    13321 aaatttaagg atggaaaaag atgaaaggaa ttattttagc aggagggtct ggtacaagac
    13381 tatatcctat aacaaaatgt atatcaaaac aaacacttcc aatatacgat aaaccaatga
    13441 tatattaccc tatgtcggtt cttatgttgg cagggataca agatatatta ataatatcta
    13501 caccaagaga tataaaagca tttgaagaat tatttggaga tggaagttca ctagggctta
    13561 acataacata tgcaattcag gagaaagcaa atggaattgc agaagcgttt ataataggag
    13621 aagaatttat aggaaatgac agagtgtctc ttgtattagg ggataatata ttttatggat
    13681 atggatttag tgaaaggttg gagaatgcag ttaaaagaaa aggagcaact atatttgggt
    13741 atcatgtaag taatccaaat tcgtttggag ttgtagaatt tgataaggat tttaatgtat
    13801 tgtcaataga agaaaaacct acagttccta aatctaatta tgctatacca ggattatatt
    13861 tttatgataa tgatgttgta gagatagcaa agctagttga accgtcagat agaggtgaat
    13921 tagaaataac ctctataaac agtgaatatc taaaacgagg aaaactaaaa gtggaacttc
    13981 taggaagagg tatggcttgg cttgatactg gtacacataa aggtctattg gatgcttcta
    14041 attatgttga agtggttcaa acaagacagg gactgtatat agcatgttta gaagagattg
    14101 catatacaaa aggatatata agtagagaac aattaatgaa actagccaag ccactgataa
    14161 aaactgaata tggtcaatat ctattaaaat tggctagtga agatatgtaa tatggtagat
    14221 aaaatttatt ataaatttta ttaagggagt ttattataat gggaaaaatc aatgttataa
    14281 agactaaaat agaaggatta tatatagtcg aaccaaatgt attttatgat gaaagaggat
    14341 attttatgga aagctataat aaaaaggatt ttatagagca gggtcttgat atgtgcttta
    14401 ttcaagataa tgagtctagc tcaagaaaag gcgttttaag aggaatgcat tttcaggtta
    14461 aatatcctca aggaaaatta gtcagagtta cagagggaga agttttcgat gttgcagttg
    14521 atttaaggaa agattcacaa acatttggga aatgggaagg tgtaatattg tctgataaga
    14581 ataaaaaaca attttatatt ccagaagggt ttgcacatgg atttttagtt ttatcagaaa
    14641 aagcagtatt tagttacaaa tgtacaaatt attattaccc agaatttgag aatggcttta
    14701 tatggaatga caagcaaata tctattgagt ggcctttaaa aggaattgaa gaaatatttt
    14761 tatcagaaaa ggacaaaaaa caaaaaagtt ttaaagatat ttgtacaaga cgttaataaa
    14821 aatttattag aattaacatt taggagaaaa aatatgaaaa aaatactgat aactggagga
    14881 gcaggattta ttgggagtaa ttttatacat tatatgctta acaagtatgt agattatttt
    14941 attgttaacc tagacttgtt gacttatgct ggtaatttag agacattaat agaaatacaa
    15001 gacaattcca attataaatt tgttaaagga gatatttcaa atagggagca ggtgtataag
    15061 ctatttgaag aagaaaggtt tgatatagtt gttaactttg ctgctgaatc tcatgtagat
    15121 aggtcagttg agaatcctga tttatttatt aaaacaaaca ttataggaac acaagtactt
    15181 ttagatgcat ctataaaata tggagttaaa aggtatcatc aaatatctac agacgaagtg
    15241 tatggtgatt taccaattga tagaaaggat ttattcttta cagaacaatc ttctatcaat
    15301 ccaagttctc catattcagc ttctaaagca tcagcagatt tattggtaag ttcttattat
    15361 agaacatatg gattgttaac aactatatct aggtgttcca acaattatgg gccatatcat
    15421 tttcctgaaa aattgattcc tcttatgatt ttaaatgctt tggaaaacaa acaattgcca
    15481 gtatatggga atggggaaaa tgtaagagat tggttacatg tatatgacca ttgtactgct
    15541 atagacttaa taatacataa aggaaatata ggggagattt acaatatagg aggtcataat
    15601 gaaagaagta atctagaagt agtaaaaatg atattaaatc ttttaggtaa atctgaagag
    15661 ttaatatcct atgtaaatga tagacctggt catgatttaa gatatgctat tgatgcaact
    15721 aaaatagaga atgagttagg ttggaaggca aaatatgact ttgatttggg tataaaagaa
    15781 actgttaagt ggtatataga aaatgaatct tggtggaaag ctgttttatc agtataactt
    15841 taaaatttag aaaggggcgt tttatattga atgagataag ttcactaatt aatatattag
    15901 cattgactca attatctggt agtaatacta caaatcaatg taattgtaca tataataatt
    15961 catctggatt tgatatgatt atgatgacct tgttaaaagc attatcacaa aataatcaac
    16021 atacttctaa tagctacaat ttattgtcta attctgagaa tttatttaat gaacttgata
    16081 atgtagtaaa taataccact agtagattta tagatgttga tacaaaagat aaaaatgtaa
    16141 agttgagaat tgaaaatgct gtagatcaag catcaaaaaa atataacgta gattcaaatc
    16201 ttataaaagc aataattaaa gttgaatcag attttaatcc aaataccgtt tcttctgctg
    16261 gtgctaaggg tcttatgcaa cttatgccag aaaactgcag agacttagga gttacagacc
    16321 cttttaatat agaacagaat atagatgctg gaactagaca tattaaggaa tacattgata
    16381 tgtttggagg gagcatagaa atgggattga tggcatataa tggtggtcct ggaagaatga
    16441 aaagtagagg agtagaatca atctctgacc tgtataaaat gccaaaagaa acacaaaatt
    16501 atattcctaa ggttatgaaa tattatagag ggtaggcttt attatgggaa taaatataga
    16561 taagctaaac ataagtccaa gtataaatat ggaggttaaa aaactaaaag agagtaataa
    16621 attttctgac aaattaaact ctttaaaaca atcttcttca ttggaagata taaaacgaaa
    16681 tttggaaagt gtaaaaaagg caggagaaag gcttgtactt actcaaaact atggcgatat
    16741 tagtatatat aaaaatgcag taaaagaata cctaaaatct gttgtagata atatgtattc
    16801 acttgataaa aatagtagct tttgggagca tcagtattat aagaatgtaa agattgttga
    16861 tagtaaactt gaggatatga ctagtaagtt aattagtgaa gaaaaagaaa acatagatat
    16921 tgtttctact gttgacatga tacaaggctt attgatagat atgtatagat aaggttatac
    16981 aaggagaaaa attttatgaa tagcaaaaaa gaggatatat atgaattgaa ttttgggcaa
    17041 ttaatagaag aaaaatctgg tgttatagaa gaaaatcaaa atgtttttaa tgcaaaagta
    17101 aatgtagctg tttctatagg aaatacaaca gaaacaataa aaaatatatt agatttaaaa
    17161 gaaggctcta taataaaatt aagtaagaat gtggatgaaa aattagatat atatgcaaac
    17221 gatagattgt ttgcttatgg agaaagcatt attacaaatg agaggttatc tgtaagatta
    17281 tctaaaatag aagatccaga tgtaaattag cattttaaat agtatccctt taggctattc
    17341 tgtatgagtt tagctaaggg gatattttta taaaaaattt aaaatatgtg tgaattatat
    17401 aaatattttt attttatgag cgataactaa attataagta tgtaattttg gaggtgaaac
    17461 tatggatatt aaaaatgtaa gttcaaatat tgtagtgaat aattatttaa agaatacatc
    17521 tggtataaaa aaagtggaag aggttaaaaa aattaataaa acagacaaga tagagttatc
    17581 taaatttgca aaggaaatgg caagtgtgtc aaatatgagt gatgagaata ttagaaataa
    17641 aaaagtcgat gaaataaaaa atgcattaga aaatggaact tacaaaataa aaccaaaaga
    17701 aattgcgaaa aaaatgatag aggatatgcg aggataaagt catgattaca gacttaaaag
    17761 ttataatata tgaagaaaaa aatataatta gtaagatgat ggaattatta aaagaacaat
    17821 ttgattatat agttgaaaaa gacttagaaa atttaaatat gttaaatcct aaactagaag
    17881 atattagcag ggagcttgca tccatagaaa taaagagaag acaacttttt ggtgatgata
    17941 tttcaatgag tgaagttgtt gaaaatagta atgatggata cttaaaagaa atatatacag
    18001 acttgaaaca cattcttgct ttagctaaaa atcaacaaga atcaaatgat tctctaataa
    18061 agaaagaact tatttttacg aaaaaaatga ttaatttcat aaaaccagct gataagcaaa
    18121 ctacaactta taattcttat ggaaatatta gaaaataaat attaggagga gaaatatggc
    18181 aggattattt tccattttaa atacagctaa ttcaggaatg aatgcgcacc aaaaagcaat
    18241 acagacaatt tctcataata taagtaatct agatacagac ggttattcta ggcaaaggac
    18301 cgagtttgcc acaaatagtc caatgtatat gcctagtttg agtaattcaa ttgcaagagg
    18361 acaattaggg actggagtac atgtaacgga tgtaacaaga gctagaaata gtttttatga
    18421 ttaccaattt agggcagaag ctcataagta tggtaagaca gtttcaaaat atgattatta
    18481 caatactata gaaactatac taaatgaacc atcagactat ggaatatctg caggtataga
    18541 tgattttttt aaaggatggg agtcattatc aaaggatata aatagtgaca gtaaaaaaag
    18601 tctagtggta gaaaacgcat ctaatttagc aactttaata agtgaaagtt ataagaagct
    18661 tgataagtta aaagaagata tagattctaa tatagacact gagataaaac aaataaatga
    18721 catgttaaaa agtcttgaag atttaaataa atctattgat attatatctg gttctggctc
    18781 tacaccaaat gatttacttg atgaaagaga tagaatttta gataacttga gttttaaact
    18841 agactttgaa aatagtgatg ttaaaaatat gcttgcagat ggtaaattag aacttaatga
    18901 attaaaaaat ccagatggaa cttggaaaac aggtatatca gggaccttac aaggcttgtt
    18961 tgaaatgcat ggtaagattg atacatataa aagcgattta aaagatgtat ctgatggatt
    19021 agctaaacag ataaatgatg tttataatac gtctgcagga ataacagtaa cagatttttt
    19081 tataacttca aatgtagatg gtgaagatat tataaagata aatccagcta taaagagtaa
    19141 cccaaatgaa ttaaagctta ctgctgatga agcttcaaaa attgctaagt taaaggatga
    19201 aaaaatagat attggggtgg ctggtggaaa agtaagtaca ataagtgacc actataaagc
    19261 ctttgcagaa tcaatcggtt tagattctca aaaagtaaat caagatgaag caaatcaacg
    19321 taaaattata aataatattg ataactcaag aatgagtgtt tcaggtgtat ctttggatga
    19381 agaaatgaca gagcttataa aaatacaacg ttcatatcaa gctagtgcaa aagttatgtc
    19441 aacagctgtg caactattgg atgttgtaat aaatggaata atttaataga agggggaatt
    19501 tataatgaga gtcagtacag gtatgatgtc tagcagctat ctaaactcac tacaagataa
    19561 tctacaaaga ttggataagg ttaatagaca agttaataca acaaaagaaa taaacaagct
    19621 atcagataat ccatataaag caataaagat attaaactca aaaagtgaaa taaagactat
    19681 ggagacttat gttgagaatt gtaaagatac agggaattgg ttagaaacta ctgatactgc
    19741 attagatcag cttggaaaat tattatcaga cataaagaaa actttggtgg caagtggtga
    19801 tggtgcatac tcagatgatg aattaaagac tcttagtaat gaaactaatg aaaaaatgaa
    19861 agaaattgca aatgctttaa atgcaacaca tgaagggaag tacatatttt caggttcaaa
    19921 tacgggggta ccacctgttg aatgtataga taatgctgat ggttcagtga gtttaaagtt
    19981 taattctagt ctaaatctta ataaattaaa tgactctttg agtatggata tagctcaagg
    20041 aataagtgta gattataacg ttaaattgag tagccttgga tttgacccaa caaaaactga
    20101 cccatttgaa gagttaaata acatatcaaa aaaattagca aatccagatg ctgatgctat
    20161 aaaagagctt acaacaactt gtttgggcga tatggaacaa ctaatagaaa atacagtaaa
    20221 tgttaggtct atatatggga caaaagcaaa tacagtagag gctatgaagg aaaaaaacga
    20281 tgatagtttg atacagttaa aggatatttt gtcacaaaat gaagaaatag attatggtga
    20341 aaaacttgtt caattaaagg cagcagagtt aacttatcaa gcttcactac aaacaggagg
    20401 aaagttattt aatgtatcta tattagatta catatagtaa aataacgcag atatgatgaa
    20461 ggttacatta aaaaaaggta tattaggttt tgaaaattta aaagaatatg agcttttaga
    20521 tatagaagat aatgattctt taaaagaatt taattctact gaagaagaag gtataggatt
    20581 tgttgttgta tctccatttg agattatcaa tgaatatgaa atagttttaa atcaggaaac
    20641 aatagaaaaa ctagaagtga aatctccaaa ggatgttgta ctatttaata taattactct
    20701 tggtcagaca tttgaagaat caactgtgaa catgaaagct cctatagtga taaatataaa
    20761 aactaatttt ggaatgcaaa taattttaca ggatgataaa tattcaataa ggcatccatt
    20821 attgagaggt gataatggat gctagtaatt tcaagaaaaa aagatgaagc agtacttata
    20881 ggagaaagca tagaagtaaa aattgtaggg gtagatggaa acaatgtgaa actagctata
    20941 tcggcgccta acaatataag tatattaaga aaagaaatat acgaaaaagt aaagagtgag
    21001 aatataaaag ctacaaataa aaatataaaa attttaaagt cattaaaata ataagcttgg
    21061 aggaagtaat atatgtatgg agaaaatcct tataattctt ataaacaaaa tgctgttttt
    21121 atggcatcaa aggaacaatt gttacttatg cttgttgatg gagcagtaaa atataccaaa
    21181 atagccagag cagctatctt agataaaaat acacagaaag cgcatagaga acttgtaaga
    21241 gttcaggata tatttacaga actaatggtt acattagacc aaaatgcagg acaatgggca
    21301 aaggatatgt acaaagttta tgattttgta agatatgaac tttcaagagc caatattaga
    21361 aaagacatcc aggtaataga tagtgtgttg cctgtaatag aacaaattaa agatacatgg
    21421 catgaagctg ataaaaaaag taaagaagaa agaagtaggg acaaataatg gaattaaatt
    21481 tagctgaatt agataagtta tcaaaagagg aattactatt gatgcttgta gatggcacag
    21541 taaaatatac caatatatcc aaagaagctc ttttaaataa cgactatttg aaagcacata
    21601 atgaacttgt aagagttcaa aatatattta cagaactaat gactacatta gaccaaaatg
    21661 caggacaatg ggcaaaggat atgtataaag tttatgaatt tataaaatct gaattagcaa
    21721 tagctgatga aaataaagat attaaaataa ttgatgatat attgccaata gtaaaacaaa
    21781 ttagagatac atggcatgaa gtttacaatc aactaaaaat ataattagat ggagggataa
    21841 aggtatgtca agtataagtc ctataagagt tacaggtctt tcaggaaatt ttgatatgga
    21901 aggcataatc gaagctagta tgattagaga caaggaaaaa gttgataaag caaaacaaga
    21961 acaacaaatc gttaaatgga agcaagaaat atatagaaat gttatacaag aatcaaaaga
    22021 tctttatgat aaatatctaa gcgtaaattc tcctaatagt atagtaagtg aaaaagcata
    22081 ctcttctaca agaataacca gttctgatga aagtattata gtagcaaaag gttcagctgg
    22141 tgcagaaaaa ataaattatc aatttgcagt ttctcaaatg gctgaaccag caaaatttac
    22201 tattaaacta aattcaaatg aacctattgt tcgacaattc cctccaaatg ctagtggagc
    22261 tagttcttta actataggag atgtaaatat accaatatct gaacaagata ctacaagtac
    22321 tattgtaagt aagataaact cactttgcgc agataatgat ataaaggcta cttatagtga
    22381 gatgacaggt gaattgatta tttcaagaaa acagactggt tcgtcatcag acattaattt
    22441 aagagtaatt ggaaatgaca atttggctca gcaaattgcc aatgataatg gtatcacatt
    22501 tataaatgat gctggtggaa acaaagtggc aagtgtatat ggaaagaatc tagaagctga
    22561 tgtaactgat gaacatggaa gagtaactca tataagtaaa gaacaaaatt catttaatat
    22621 agataatatt gactataatg taaattcaaa aggaactgca aagttgactt ctatcactga
    22681 tactgaagaa gctgttaaaa atatgcaagc atttgtggat gattataata aactgatgga
    22741 caaggtctat ggtttagtta ctactaaaaa gccaaaagat tatccacctc ttacagatgc
    22801 ccaaaaagaa gatatgacaa ctgaagaaat agaaaaatgg gaaaagaaag ctaaagaagg
    22861 tatacttaga aatgatgatg agttaagagg ttttgttgaa gatattcagt ctgcattttt
    22921 tggagatgga aaaaatatta ttgcattaag aaaactaggt atcaatgaaa gtgaaaatta
    22981 caataaaaaa ggtcaaatat catttaatgc agatactttt tcaaaggctc ttatagatga
    23041 tagtgataag gtatacaaaa cactagcagg ttattcttcg aattatgatg ataagggaat
    23101 gtttgaaaag ctaaaagata ttgtatatga atattctgga agttcaactt ctaaacttcc
    23161 taaaaaagca ggtatagaaa aaactgcttc tgctagtgaa aatgtatatt caaaacaaat
    23221 tgcagagcaa gaaagaaata taagcaggtt agttgaaaaa atgaatgata aagagaaaag
    23281 actttatgct aaatattcag ccttagaatc tttgttgaat cagtattctt cccaaatgaa
    23341 ttatttctca caagcacagg gtaattaatt atggataaat taaaagaaaa attaaattta
    23401 tataaagata tatctttaca aattataaat ttgattgaaa aggaagaata tataaagata
    23461 agtattaagt taggtgaaag acaagagatt ataaatagtg taagtgaaat tgatagaaat
    23521 gattttatac agctttataa tagaatggaa ttaattgaaa ttgatagcag gataagagat
    23581 attttacaag gacaattatt agaagtaaaa aaagaattac atgagtataa gcttactaaa
    23641 caagtgaaca caatgtatta taacttaaat agagaaaaag taaatatttt taataaaaaa
    23701 gtataaagtt atgtaccatc ttgtccgatt atataaatga agaattaata aaaaagatta
    23761 aaagtagaaa tgacaaggat gtcaactata ctaaggaggg taaaataatg agagttaata
    23821 caaatgtaag tgctttgata gcaaataacc aaatgggaag aaacgtaaat gcacaaagta
    23881 agtctatgga gaagctatct tctggtgtta gaattaagag agctgctgac gatgctgctg
    23941 ggcttgctat atctgaaaaa atgagagctc aaataaaagg tttagaccaa gcaggaagaa
    24001 acgttcaaga tggtatatct gttgtacaaa cagcagaagg tgcattagaa gaaactggta
    24061 acatactaca aagaatgaga actttatcag tacaatcttc aaatgaaact aatactgctg
    24121 aagaaagaca aaagatagct gatgagttac tacaattaaa agatgaagtt gaaagaatat
    24181 caagctcaat tgagtttaat ggtaagaaat tacttgatgg aagttctaca gaaataagat
    24241 tacaagttgg agcaaacttt ggaacaaatg ttgcaggaac atctaacaac aacaatgaaa
    24301 taaaagttgc tctagtaaat acttcaagta taatgagtaa agcaggtata acaagttcta
    24361 caatagcaag cttaaatgca gatggaactt ctggaacaaa tgcagctaaa caaatggtat
    24421 ctagcttaga tgtagctctt aaagaattaa atacatcaag agcaaaatta ggggcacaac
    24481 aaaatagact agaatcaact caaaacaact taaataatac tatagaaaat gttacagcag
    24541 ctgaatcaag aataagagat acagatgttg cttcagaaat ggttaactta tctaaaatga
    24601 atatattagt tcaagcatca cagtcaatgc ttgctcaagc taatcaacaa ccacaaggag
    24661 ttttacaatt attaggataa aataattttg tatattggat atagaagaaa gggtaaggct
    24721 ttgctttact cctttctttt tttacaaata tacttttgaa aggaaaattt atatgttact
    24781 tagtatagtt atgattgtta aaaatgaaga aaaaatactt gaaaaaactt taaaatcatt
    24841 aaccacatta agaaattcta tagaaagtga acttataata gtcgatacag gttctacaga
    24901 tgatactata aaaatatcta agaagtacac ggaaaaagtg tattttcata attggaataa
    24961 tgatttttct agtatgagaa atatatcaat atcctatgct aaaggtgaat ggttacttat
    25021 attagatgca gatgaaatac taattgattc ttcaactatt gtaaaatttt ttaaagatgg
    25081 tcttgataaa aaatttaatt ctgcttcaat acaattaaaa aatctttact catatgataa
    25141 aaaattatat ggatattgtt cagtgcttag actttttaaa aacgttgatt ttagatacca
    25201 tggtaaagta catgaacaac caatatacaa aaaccctata tttaataatg ttgctgattt
    25261 tgaacattat ggatatttgt ttgaagatga agaaataaga ttaaataagg tgaaaagaaa
    25321 tgaaaaacta ttatttcaag agttaaaaga gaatgataat tctccatata caaactatca
    25381 attagggaaa aattttatta tattaggaaa atatcaggag gctttatact atcttgagaa
    25441 atcttatgaa ttatattcta aactagaatt ggcacctggt tacttgataa caagccttgt
    25501 aaaaacatat ttatatttag gaaaacataa gaagtgtgaa agattgtgct taaagtatat
    25561 taagaaagac atgaataata ttgatatata ttattatatt gcacaagcac aagtagattt
    25621 aggaaagtat gaaaatagta tagattcgta taagagatat atttacttgt tagataatta
    25681 tgaaataagt acacaagcaa atagtttatt ttcagacact gatactgtag ggcttagaga
    25741 tgaggctatt attacactga taaagattta ttataagctt gaaaaatatg agtttgtaat
    25801 ttcagagtac aataacattg aagatgtgga aaagaaaaag aatgtgtact ttagcttatt
    25861 tatgtcccta tataaattga atagatttga agatataaaa aattattata aagaagtttc
    25921 aaattctaaa attgaaaaaa atagttttta tagaaatata gaagaagtta taaataatat
    25981 taaagaggat gaaaaagagt atgtatataa aatcctttgt gacattgaag gtaattatgg
    26041 cattttaaat caaataagga taaataaatg tgtatctata gataaatgta aagaaatact
    26101 aaatgaagaa aaggaaataa tttatgcata tattataaaa atagcttttg aagagaagat
    26161 tgatttacta gatatttttt atgaaatgga atatgtatgg atagagaaat atctaaaata
    26221 tcttttagca ttagaaagaa gttttaattt agtactatat aagtacataa ttagtcgtcc
    26281 aaatacatca gatatggaaa agataagagt atataaagct atatctaaag tagttttaga
    26341 aagtataagc ttaagtgatg aaaaatataa ggagattttt tatttttata taatgtattc
    26401 ttataagtat ataagataca tatatagcaa tttaagtgat tttgaattaa aaaaatttgt
    26461 ttgcaatgat ttagataagt tcactataga atttaagcat ctacttgaca ttaaaaataa
    26521 agtaaataat gctaatgaaa aattagagta tatacatagt atgaggaaat tactaaatga
    26581 gtatcctttt tataataaaa taataaaaat acttataggt gaattagaag aaaatataaa
    26641 agaaagtgaa gaatttaagg atttaaaata tagttttatt attagtatag aaaatatgat
    26701 tgaaactggc aaaataaatg atgcgaaatt attggtagat gactattcaa aaacatttgt
    26761 ggatgatgta aggattttaa atataaaggg aattttatat atgtttgaaa ataagcttga
    26821 taaagctgat tttatgttaa aaaaggcatt atcattagat gtagaaaatg aagatactat
    26881 atataatata gaatacttaa aaagtttaag ataagtcaaa aataggagaa ttgaagaatg
    26941 aatataccaa tagtggttaa tgaaaaatct aaagacataa taaaagattg gcaatataca
    27001 tgtacaaatg aagatataaa atttacaagc ataataatat tgacatataa tcaaatagaa
    27061 tatactaaat tatgtattga aagtattagg aaatttaccc caaagaataa atatgaaata
    27121 ataataattg ataataactc ttctgatgga acagttgagt ggttaaaggg acaatctgat
    27181 ataaaatctg tgtataataa caaaaactta ggatttccaa aaggatgcaa tcaaggtatt
    27241 gagttagcta ctggtgaaaa catattgttg ttaaataatg atgtaatagt tactccaaat
    27301 tggctctata atttgaataa agctttatgg tctcaagata atataggtgc tgtaggacct
    27361 attacgaatg catgttcata ttatcagcaa attgatgttg attataagtc aattgaggac
    27421 atgtttatat ttgcacacaa aataaataaa tctaatatta acctatggaa atatagattg
    27481 aagttagttg gattttgcat gttaataaaa aaaactgttc tggataatgt aggggtttta
    27541 gatgaattat tcacacctgg aaattttgaa gatgatgatt tatcttttag gatgatagag
    27601 tcaggatata agttattatt atgccaggat acttttatac accattttgg aagtgtgtct
    27661 tttaaagaaa atcgtaataa atatacagat ataatgtata ttaatagaag aaaatttgaa
    27721 actaagtggg gatttaatcc agaatatagt ggaatgataa gaacagattt gatttctaaa
    27781 atagatgata gtttggaggc aaatattaat gttttagaaa taggatgcgg tataggggct
    27841 actcttttag aaataaaaaa tatatataaa aatgcatcaa tatatggaat agaaattagt
    27901 gagtcagcag gtaaacttgc aaagtatagt gcagatgtac ttatagcaaa tatagaaaaa
    27961 gtaaaattgg attataaaaa agattttttt gattatataa tattgggaga tgtacttgaa
    28021 catttgattg acccatggaa gatagtcaat gaattgaaac aatatctaaa gaaggatggt
    28081 tatctggtat ctagtatacc aaatattatg catgtttctg ttttaagaaa tcttgtgtta
    28141 ggtaatttta catatgaaga ttcaggaatt ttggacaaga ctcatttaag gttttttaca
    28201 ttaaatgaga taacaaaaat gtttaatgat agtaattaca taattaatag tattacagct
    28261 actagtatgc cactttcgga aattgataat agcttcattg atacaatatg taaggaaagc
    28321 tgtaaagaaa tgagacaaca gtacgaatct tatcaatata tagtaaaagc ctctaaaatc
    28381 ctagatacta aaagatattc tagtattagt atgattaatt taaaatacgc tttaatgaga
    28441 attgataatg aattagatgt agatagtaat ttaagttata tatttgataa ttataatata
    28501 actgaaccat gttttgttga tgatattgaa tatctaattg atacatttgt gataaataaa
    28561 gcaactctat taaatagatt aggagttgag gcatttaaca gaggtctagg agattttagt
    28621 ataaacatgt ttatgacagt attagagatg gatagagatg atattgactc aatatataat
    28681 ataacaagtg tattatgtga attagaagaa tttgatactg cttataattt aattaaaaat
    28741 agtagcgaaa aagtacagag tgaaagtgat atacaagaga tactttgttt tattgagggg
    28801 aagaaatatg aataatgata agatatgttt tataacctgt gtaaatgatg aaaggcttta
    28861 tgaagaatgt cttgtatata taaatagcct agacattcct aaaaacttta gtatagaaac
    28921 agtagcttta agaggagccg attctattgc ctctgcttat aataaagcta tgagagaaac
    28981 agattctaag tataaggtat acttacatca agatactttt ataattaata aaaatttcat
    29041 acatgatatt ttagagatat ttaaaaaaaa tacagatgtc ggaatgattg gtgtagctgg
    29101 agtaaaagat atgcctgtga atggaatttg gtgggattct gataaaaaag cagggaaagt
    29161 atatgatagt catacaggta aaatggatat ttatgaattt agtaactttg aagaatgttt
    29221 taatgaagtt atggctatag atggattaat tatgattact caatatgatg tattttggag
    29281 agaggataag tttgatgggt ggcattttta tgatttgtca cagagtatgg agtttagaca
    29341 aaataaatac aaagttattg taccaaaaca aaataagcct tggtgtatgc atgattctgg
    29401 agtagtaaat ataaataatg gatatgatga atataggata aaatttgtaa aagagtacat
    29461 aaatcttgat ttatatagag aaaattttta tgaatttgat aagaagaaag caagtaccat
    29521 acttaagagt aataagcatg taatggattg tatgaaagag gagcttacag aacaattaag
    29581 attaaagaat tacaaggatg ttttaggtat tgtttctaaa attgctcatt tttctgtttt
    29641 taatcatact ggtttgtatt cttgtgaaga atgtgagaga gcattgctag aatgtgcaaa
    29701 taatttacca gaaatagaaa atacgaaatt atttacaaaa aaagatttaa aaagaagaaa
    29761 agtattacat gttttaagtg aaggatattc aacaggaggt catacaagac tagttaaaaa
    29821 ttggattgaa attgacaaag actctgttca ttcagttgta actacatggc aatcagatac
    29881 actgccagac tggttattaa aagcaataaa tgatagtggt ggcgaagtta tatctttgga
    29941 tttaatttca gatgattatt taaaaagagc tgtagctttg aggaaaatag cttatgactg
    30001 ggctgatata gttattttat atgttcatat gtgggataca atacctgttg ttgcttttgg
    30061 agttgatggg aaaataccta ttttacatgt taatcactat gatagtactt tttggttagg
    30121 gacaagtatt gcagatattg tcattgattt tagcgaaact agtcaattaa ttacattaga
    30181 taaaagaggc atagataaat ctgaaatatt accaatgcca ttaaaagaaa aagaagtatt
    30241 ttcaaaatct gaagttagaa aacgatataa tttagaggat gatgtgacaa taatattgac
    30301 tattgctagt gaaagaaaat acaatagtgt aaatgatatt aattacttta aaattgctaa
    30361 aacattgatt gaaaatacag ataatacaat tattattgtt gtaggagttg atacagagaa
    30421 tctctattgg aaaactttaa gtaatgttac agataataga gttatatgtt ttggaacaac
    30481 agcaaatata gatgattttt ataagatttc ggatatatac ctagagtctt tcatggtagg
    30541 aagtcatact tcaaaattag atgcaatttt atatgattta attcctgtta agtttaaaaa
    30601 tgaagtttca ccaattttta caaatatgtg gaattttata gataagtttg attataagaa
    30661 tataaaagag gttatagaca tgataagaag gtacaatact agtgaatttg acagggataa
    30721 gataaaagca aaacaatcgg aaataaaaca ttttgttata gataaacact gtattgaaat
    30781 aaaaaactat atagacaaaa tatataatga agttaatcat cataaagtta agtatgattt
    30841 atataaaaat gatgaaatcg aggactatca gctttttgta gcattatatg gctatatggt
    30901 aaaaaataaa aacatgtcat aggtggtaaa atgaacaata ttcatatcaa taaatttgaa
    30961 aaaagctgtg aaaaaaactg ggattatttt gtagaaaata aatctataaa tggtacattt
    31021 ctgcaaacta gaaatttcct taattatcat gaggagggaa aattcactga ccactcatta
    31081 ataatatgta aaggtgaaga aatactagca gtcgtacctg catgtgaaac ttatgaagat
    31141 ggtgaaagaa tatttttttc tcatttaggg agtacttttg gtggcattat aataagaagt
    31201 ggttttaatg atattaggca tgtaaatgcc attacaaata agttagaaat atatttacag
    31261 gaacaaaatt tcgataaagt atatttaaaa aatacatcaa gaatattttg taaagaggat
    31321 acttcattac tagaatattt tttatttaag aataattaca tgttttatga tgaattaagt
    31381 atgtttttag aattaagtaa gtataaagaa gatatattag ccaattttaa atacagtaaa
    31441 agaagagatt ttaaatattc tttgaagaat aatcttacct ttaaaagact gtatagtgat
    31501 gaagatatag tttgtttttt taatttactt tctaattgtt tagatagtaa aggagctaaa
    31561 gtaatacatt cagtagaaga acttttggag tttaaaaata atagattaaa agatattgta
    31621 gaattttatg cagtatatat tgatgacatt atgatttgtg ggagcatggt atttaacttt
    31681 caagaaagag tttatcatac tcaatatcta gcatcaaatt cgacatataa taaatattat
    31741 ccaatgatat ttttatacta taatctaata aaagatgctt tagagagaaa ttttaagtat
    31801 ctttcttttg gaattagcac tctaaataga ggcaaatact tagatgaggg tttagctaca
    31861 tttaaagaag gttttggttc aagtgcaatt tgtaacagaa catactataa aaatataaat
    31921 aagtgagaat catgttttat agagttttta gagtatagta aatatctagt actataatat
    31981 tacataaaaa taattagttt ataaagaagg tttgtatatg aaaagattaa tgattttagg
    32041 ctcaattaag tattttgaga atattgttat gtcagctaaa agagagggaa tatacacaat
    32101 tgtttgtgat aatagaattg atactcctgc gaaaaagatt tgtgatgaag caatagatgt
    32161 tgatgtattt gattttgata aaataaagaa tatagctata gataaaaaga tagatggaat
    32221 tttaactgga tttacagatt ctttaatgaa gccatatgtt tatattgcaa atgaactaaa
    32281 tttgccatgt gtgatttctt gcaatcaact tgaatctgta actaataagg ctgttatgaa
    32341 aaattatttt aaaaataatg gaatacctac aactgattat tgtattattg aaagtttgaa
    32401 agatttagaa aaaatacaag gattaaattt tccacttgta ataaaacctg ttgatggtta
    32461 tggttcaaga ggtgtatatt ttgtatcaaa catagaagaa ttaatagaaa aatttgaata
    32521 ttctaaggaa gcctcgcaag atggacaagt aataattgag gaattttatg aaagtgagga
    32581 aatacaagga ctagcttggg ttcataatgg agagtcacat gtattttata ttggagatag
    32641 agagcttgta aatatacata caggaagagc tggaaaacca gatagattaa tttatccatc
    32701 aaagtattgt tttcaatatg aagaagaaat aaaatccata tatcaaaata taacgcaggc
    32761 ttttggcata aaaaatggac ctctttatgt acaaatgtta gtgggagcat atggaataaa
    32821 ggtatctgaa gtaatgccaa gattacctgg aggttgtgac tatatggcta tttctcaaat
    32881 aacagattta gacataggaa gtttatttgc aaactttagt gtgaataatg aagtaaattt
    32941 tgatgaaata aagaaatata atatgcatct atcaaaatgt gtatatgcat taccaatata
    33001 cataagacct ggcacaataa aaaagataaa taatatagat aaaatagaaa acttagatta
    33061 tgtcactcaa tttctattac tagtaaaaga aggagataca ataggattat atgaagatga
    33121 gagacaggat tgtggaagag tttatggagt agcaaataat gtatttgatg caaatataaa
    33181 gaagaaatgt attcatgaaa tgatagaaat acttgatgaa aataatgaaa atatgataga
    33241 aaatttttaa ataagggagt atgatagata tgaagctaat aactcatgaa caaattatgt
    33301 cattaaacat ttctcagaaa caaggatacg agtggataaa agaatccttt ttaacaaaaa
    33361 aagattgtca attaccacca aaaataagca tggtagaaga agggcatgta ttttacaatg
    33421 taatgccgtc cctaaatcat aatcataaga ttggtggaat aaaaatggtt acaagattgc
    33481 cagggagaaa tccaagttta aattcagaga tatttctata taatatggaa gatgctaaat
    33541 taaaggctat tttagatggc aattatatta cagcttttag gactgctgct gttgctgcct
    33601 tggctatcga tacatttgct aaaaaagatt ttaatactat tgctattatg ggtttaggtg
    33661 taactgcttc tgctataatg aatatgcttt catatactct taaagataaa aatataaata
    33721 taaagttact taaatataaa gaccaagcag agtcgtttgt aaaaaagtat gaaaaaaatg
    33781 aacaatttag ttttgaaata tgtgacacac atgaagaact tattgtagat tcagatgtag
    33841 ttatttctac tgtgacatat acagatgaat atttatcaga atttaaatgg tttaaaaaag
    33901 gtgctttatt attacctgta catgttatgg gatttggaaa tgttgattat ctatttgata
    33961 aagtatattt ggatgattat aatcatttga aacatctaga aaatatagat agatataaat
    34021 attcttgtga attttatgat gttttaagta aacaagctaa aggaagagaa aatgatgatg
    34081 agagaataat atcttacaat ataggtttgt caatacatga tatattattt gcaaataaaa
    34141 tttacgaatt gtgtgaaaca ctaagctgtg aagaaataga attaaaagaa ccaaaagaaa
    34201 aatattggat atagtttatt tcattcatat ttacaatagt ttattgtaaa tatgaatatg
    34261 aagtaatata ttgttagaaa attagcatga ataggataga taaatttatg gataaatata
    34321 atttaattag gttcgtatct attggaaacg aatatatagg aaatttagtt gcattagaat
    34381 caaataaagc aatacctttt gatataaaga gagtttatta catatatgat gtaccaaaca
    34441 atgtaaagag aggatttcat gcacacaaaa acttggaaca agtactagtt tgcctaaatg
    34501 gaagtgtgaa gataaaatgt tatgatggtg taaaagagac tatatttaat ttacataaaa
    34561 atgatgttgg attatatata ggaacgggag tgtggcatga gatgtttgat tttgatgaaa
    34621 aaactgtttt aatttctata gcatctgaac attataatga agaagattat attagagact
    34681 ataaagaatt tttaaagtat ttaaataatg tgtagttatt atacaattag tgatgtattt
    34741 tcttaattaa ataaatttaa gatagccaca tagagaatag atagattagg atgtgaattt
    34801 attgttggtt aaatttaata atttattaaa acagttccaa actcataaag aagaatatga
    34861 acagaagatt aaggatgtaa tggaaagtgg atattatatc cttggaaatg aagtaaagca
    34921 ttttgaagaa gaatttgcta actatgtagg tagcaaatat tgtgttggtt tagccagtgg
    34981 tttagatgca ctgataattg cttttagagc attaggaata agcaaaggtg atgaagtaat
    35041 cgtgcaatca aatacatata ttgctagtgt tatgggaatc agtataaatg gagcaacacc
    35101 agtatttgta gaaccaaatg aatattataa tatagattca tctaagatag aagaaaagat
    35161 aaatagcaaa acaaaagcta tattagtagt gcatttatat ggtcaagcaa gtaatatgaa
    35221 agatatacaa gaattatgtg ataagtataa cttgtattta attgaagatt gtgctcaatc
    35281 tcatggagct aaatatgatg gaaaaatgac aggaacattt ggtgatatag gttgttttag
    35341 tttttatcca agtaaaaatt tgggtgcatt tggagatgca ggagctatag taactagtaa
    35401 tgaggaaata gctgataaag tgaaaattct tagaaactat ggctcagaaa agcgatatta
    35461 taataaattt gtcggatata attcaagatt ggacgaaatt caggcaggtt tattaagagt
    35521 aaaacttaaa tatctaaatg aaattgaaat tgaaaaatca aaaatcgtag atagatatct
    35581 taatgaaatt aataatccca aagtcatact tccaaagata gaaaataatt gtactcatgt
    35641 atggcattta tttgttttac aagttgaaaa acgagataca tttatggaat acttaaagaa
    35701 aagtggtata gagtctataa tacattatcc gataccacca catctatctg aagcatatgc
    35761 ttatttggga tataaaaagg ggagttttaa tatagctgag aactattcag ataaagttgt
    35821 tagtatacct ttatttattg gtatggaaga tgaagaagtt agttatataa ttaaaattat
    35881 aaatgaata
//
LOCUS       DAMKNB010000035        35156 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.037, whole genome shotgun sequence.
ACCESSION   DAMKNB010000035 DAMKNB010000000
VERSION     DAMKNB010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 35156)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35156)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35156
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.037"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            complement(70..2199)
                     /locus_tag="PC494_001931"
     CDS             complement(70..2199)
                     /locus_tag="PC494_001931"
                     /EC_number="1.11.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxiredoxin"
                     /protein_id="HDF3912432.1"
                     /translation="MPNLPSLGSKAPDFKANTTNGPIRLSDYKGNWIVLFSHPGDFTP
                     VCTTEFLCFAKYYDEFKKRNTELIGLSVDSNSSHLAWMYNISLLTGVEIPFPIIEDRD
                     MRIAKLYGMISKPMSDTSTVRSVFIIDNNQILRTILYYPLTTGRNIPEILRIVDALQT
                     SDRDNIVTPANWFPGMPVILPYPKNYKELKNRVNSCNKKYSCMDWYLCFVPDNYNDEE
                     VSKKIDNTCSWKKEHTKNIENECNCEHEHHDYLNKALDCKQEHKTDIKDDCNHEKKHT
                     KNTNKVHNSKQDKFKDKSCDEMNFNYDKDESCDKINSSYNKEDSSYEDFYKHNYKNYD
                     YTSEKNTKKIAMKTLKDSKKLVRPQITDPYNPIVENANCPDINPIVAEYVLGNPTNVD
                     AQLLDAVIFAFAEIDQSGNLFIPYPRFLNQLLALKGEKPSLKVIVAIGGWGAEGFSDA
                     ALTPTSRYNFARQVNQMINEYALDGIDIDWEYPGSSASGITSRPQDRENFTLLLTAIR
                     DVIGDDKWLSVAGTGDRGYINSSAEIDKIAPIIDYFNLMSYDFTAGETGPNGRKHQAN
                     LFDSDLSLPGYSVDAMVRNLENAGMPSEKILLGIPFYGRLGATITRTYDELRRDYINK
                     NGYEYRFDNTAQVPYLVKDGDFAMSYDDALSIFLKTQYVLRNCLGGVFSWTSTYDQAN
                     ILARTMSIGINDPEVLKEELEGIYGQF"
     gene            2465..2713
                     /locus_tag="PC494_001932"
     CDS             2465..2713
                     /locus_tag="PC494_001932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3912433.1"
                     /translation="MMICFAMTFALVLINSVMGVHIGLDYYFLMGSVLTVCLTIGIVL
                     CNARKIFDSKAIHKTRTKTVSNNKKQKSHSRDIKRKIS"
     gene            2879..4270
                     /locus_tag="PC494_001933"
     CDS             2879..4270
                     /locus_tag="PC494_001933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiD family decarboxylase"
                     /protein_id="HDF3912434.1"
                     /translation="MNFRDLFEKAVDFIDEKRKSIVAISLSTLGVIALIIVFFLSSNE
                     FSVGNEANELLKIIEKRQYSIAVDYYTSIEKKFSDSKMERFNKSVSKKINKLLLNSGD
                     KYLDGDISQESFIGLINTVKELNKISIDVDDLLAQADRVREMYKEENTTYDIAINYIS
                     TVSILNGMGSNLDVYKQNIETIKESRDVYDSAVKDQKAYKYYEAIEKYNKVLKEDEKY
                     YSMAQNGKEQCIEEMYDYYISRAEEANTSGDYERALQYIEYLKDDYSDDEKVQSLEKK
                     YKKNLSLYTLTSDDIINVIAKKSGKDKANLSINSLPQMIKNNKYYYAEVYEYDKLINE
                     VLVSAKTKDLYSYKDGKKDYKVDYGDGYFRILEDGSYQFGITKDKAKFVLTNTLDEKE
                     NKYKKIEILDIEKADRYVKSKKSLEELFGKYKNIYYYAVVNKGLFRGKEVYAINIYNE
                     KIYAISENGLNEY"
     gene            4385..5854
                     /locus_tag="PC494_001934"
     CDS             4385..5854
                     /locus_tag="PC494_001934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanW family protein"
                     /protein_id="HDF3912435.1"
                     /translation="MSNVNKKLVIAIGAVALVVIIFIGIMCMQFKGEKIAKNTYVNGV
                     NIGKLTKSQAKQELAKKYKLENVDFNYNDKSWKVKSKDLNLSTDLDKTVENAYNLNRK
                     SAFFGNLSKTISANFGKKSNLVVAINYDKNKLKAEMEKIAKEIDVDVKDATLDISGEK
                     VKVIPDSDGLKMDISKSMENFDNQTKKGNYKNELVVKATPAKVKKEQLANIDTNLGTY
                     STTFKTSQINRSINIKLATDNISNVLLMPGETFSFNKHTGKRSKENGYKSAPVIMEGE
                     MEEDYGGGVCQVSSTLYNSVLYAGLEIVNVKNHTIPSSYVPKGRDATVADSGIDFLFK
                     NNLKHPVYIKNYVSGNQIVCNIYGSAEDKQNITISTKLDGVSQTTMKRVNDPTMPKGK
                     EKVDKSGRNAYSVSTYRTFNDANGKKIKTEKIANSYYPKKEGIILVGTMEPKPEEKPN
                     TDENKNNQNTNNQNPNNQQKPETPPTDNKPNETQPQPQA"
     gene            5919..6512
                     /locus_tag="PC494_001935"
     CDS             5919..6512
                     /locus_tag="PC494_001935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fis family transcriptional regulator"
                     /protein_id="HDF3912436.1"
                     /translation="MNLNNITNYVQSICENISNVLDVDVTLVTKDLTRIAGTGIFRGK
                     IGETISEKSVYSLVLKDGKSYVINKEIEENCNKCANRENCKELADICTPVKMGEHILG
                     ILGIAAFNEEQKEKILSKDKELTAFVRSMSDLISFKLDELYKQEVKTIDDLEREAIEN
                     AIKKYGSNTEGMKKVAEALNIGIATLYRKVKKFNIKS"
     gene            6694..8040
                     /locus_tag="PC494_001936"
     CDS             6694..8040
                     /locus_tag="PC494_001936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HDF3912437.1"
                     /translation="MPRKILDISLIEDNKSDLTFFNIEEEDGDETLKALKQSYVTTNY
                     KEETLLNLQGALNSKSDTTSKELKLESYKRYNNALDLAYKNYITSAINMVNKALEINP
                     KDIDILNLRGLLKLLKCDFAKSFESFYTALCYENNHISRKYVNLISSEDFKTFLGRYN
                     HSIRFINEELNYESIHILENIIEEEPELIEPYVILSLLYDKLGNVKKREGYLDKLKEL
                     DKDNPVFEKNEEEKEDTSKKEEIKKVKRKKSILPYIIVGCVLIGMGIYLIQSKKRIEN
                     LNNQISSKEEKLSETDKKLGETSKKLEKTNKELNEVKNKEPEREITVADEEDLYYQAL
                     NLKKNKEYEKAIDNFKSVVSSGKTKKYISESIYQLAITNKLLGNKDEAIKYYKKYINT
                     YTKNDQYYDDSYYELGMLYYDNGDLKNAQQTFYSLRSEVPDSMYNNSKIKEILSEK"
     gene            8222..8593
                     /locus_tag="PC494_001937"
     CDS             8222..8593
                     /locus_tag="PC494_001937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CidA/LrgA family protein"
                     /protein_id="HDF3912438.1"
                     /translation="MKVFNQLVIILSIWVIGEYISSFIQGIILIPGSIVGMLLLFLLL
                     QFKVLDLSSIENVSGFFLDNMAIFFIPAGVSLIKSLDLIRENVLVLLLVICLSTLIVM
                     YTTGIIVEKMIKKKEEGQKNV"
     gene            8586..9275
                     /locus_tag="PC494_001938"
     CDS             8586..9275
                     /locus_tag="PC494_001938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LrgB family protein"
                     /protein_id="HDF3912439.1"
                     /translation="MYNVLQTPVFGIIVTIVFFNLGRYIQRKTSNPICNPLLIAIVGI
                     ILFLSISKIPYENYKIGADSLNFFLGPVTVVLAVPLYKQFELFKKHMFEIIVGIGCGI
                     VISFVSVLIIGKIANSDVSIINSLIPKSITTPMGISLANSLNGVESITVVAIIFTGIF
                     GGMVASTVFKLGNINHPVAKGIALGTSAHALGTTKAFELGEIEGAMSGVSIGVSGTIT
                     VILIPIIMNFI"
     gene            9795..10661
                     /locus_tag="PC494_001939"
     CDS             9795..10661
                     /locus_tag="PC494_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HDF3912440.1"
                     /translation="MSEVKNTLQKHPVLRYSTMLFGMLMTSIGINGFLRPAHLLSGGA
                     TGIATSINYLTNINVGLLTFLINIPIFILGFIYLEKEFCISSLVNMIVFSLLLGATQE
                     ISNIIPIHDILLQSVYGGILSGLGVGVVFRTRSSQGGTDIIAAILKIKKNIEMKDTAL
                     AINGLIVLTGSFLFGLDLALYTLIGLFLNAYSMSFIKDAMNYQKSVMVMSNEVDLIAE
                     DIMKSLVRGVTFLDAEGAYTHQKKKIIYTIVSSNEIPKIKDIALKYDKKAFISVNDVT
                     EVKGRGFKAKDL"
     gene            10903..11712
                     /locus_tag="PC494_001940"
     CDS             10903..11712
                     /locus_tag="PC494_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3912441.1"
                     /translation="MNLSKEYVNLYDNYLKYINEVNKEIRSIKNMKKRVLKRGDFAPE
                     NEVLELEGKTIRDIDDVDTKKPKNKIYKFSNGDVYVGKFLEGKMEGKGSYTFFVDEGT
                     VMEYIGEFKEDKKNGKGNFIFSNGNEYIGYFEEDMMSGIGNMLYSSKDEYIGTWKNGK
                     KDGKGIYKWSDGCIYAGEFKGGKMEGYGICYNSKGEVLYEGEWKNNLIHGKGTYIWEK
                     GKKYIGEFMHGKKHGQGTFYLNNELVYEGTWKFDKPSIFDRTLDEIFSLRL"
     gene            11856..12920
                     /locus_tag="PC494_001941"
     CDS             11856..12920
                     /locus_tag="PC494_001941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HDF3912442.1"
                     /translation="MKRLIALVLVVLIVLFYSPELLKEGYDLKEKFFQSEIWNEFLDK
                     ININDNSKKDKKEKSQNLQSNNTEGENLGESDIKNFEKISLGDNLSYVLSSIGKPGRI
                     DISEYGFDWYVYNQYGKEFAMVGLENDEVVALYSNSINSCENQDIKLNQDRQTVRTKI
                     TPLKYKRKGNTRYIINSENQYDIISKEGKYITIFYDIHEENRVCSYLIIDKSTEDEFK
                     NLYPDDSEELKKCFELEVIDLVNSVRNQRGLNSLRYSEQATLSSRKHSEDMRDNNFFD
                     HVNKKNETPFDRMKREGIVYTSAGENIAAGQINAIYAHEAWMNSEGHRKNILGNYNNI
                     GVGVIFGGSYKTYYTQNFYK"
     gene            12948..13667
                     /locus_tag="PC494_001942"
     CDS             12948..13667
                     /locus_tag="PC494_001942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HDF3912443.1"
                     /translation="MTSWKKKTVYKCLIAVALFCGIVLISNFSKVSALMMDTNGNVLI
                     KHGSREKKLIAITFDDGPHPKETSQVLDVLKKYNVKATFFIAGKHAKWYKEPLVRASK
                     EGHEIGNHTFNHPDISNLSSSQIEEEIVKCEDILKEVTGKKPTLFRPPFGSYREKDLI
                     EIAKKHDYKVVLWTGVDVKDWKNPGANSIADKIINKVQNGDIILLHDYATNDTVEALD
                     MFIPKMIEKGFKFVTVSELIK"
     gene            13691..14275
                     /locus_tag="PC494_001943"
     CDS             13691..14275
                     /locus_tag="PC494_001943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate/anthranilate synthase
                     component II"
                     /protein_id="HDF3912444.1"
                     /translation="MILMIDNYDSFVYNLVQYIEELGEAVVVKRNNEIKISDIEELNP
                     EVIVLSPGPCSPKEAGICIDIVEHFKGKKPILGICLGHQTIGHVFGGDIIKAQQPVHG
                     KVYSINHTNKGVFRGLKNPLNVTRYHSLIVDSNTVPKELEITAITDKGEIMGIRHKKY
                     LIEGVQFHPEAILSEYGHEMLKNFITEARERVHM"
     gene            14277..15626
                     /gene="pabB"
                     /locus_tag="PC494_001944"
     CDS             14277..15626
                     /gene="pabB"
                     /locus_tag="PC494_001944"
                     /EC_number="2.6.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate synthase component I"
                     /protein_id="HDF3912445.1"
                     /translation="MIREINTKLNSFEIFTIFRNEHDSFILDSAMDKEKLGRYSFISS
                     QPFKVLKYKDTDENPLEVLKEELHKYRVVNDTNLPFVGGAVGYLSYDLGNYIENLPRT
                     AVDDIEMPDMYFGFYNHVIVIDHLVQKTYIATPNIDIELEEKIIDDIEQRILKEEKKG
                     IDSICYEEKEVTPIRLKSNFTKEEFKNAVQSVREYIRQGDIYQANLTQRFSGETELTS
                     FELYRDLRRFSPAPFGAFLNFEDAHILSNSPERFIRCVNKRIETRPIKGTRPRGKDKE
                     EDLRLQQELRNSEKDRAELLMIVDLERNDIGRISKTGSVKVPELFVIEPYANVNHLVS
                     TVVGELKDDKDATDVIKATFPGGSITGAPKIRAMEIIDELEPTQRNVYTGSIGYIGFN
                     GDMDFNIAIRTIIKNDKKVYFQVGGGMTWDSDPDEEYQETLDKAKSIMKALRGYYEE"
     gene            15616..16359
                     /locus_tag="PC494_001945"
     CDS             15616..16359
                     /locus_tag="PC494_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class IV"
                     /protein_id="HDF3912446.1"
                     /translation="MKNNVGFDSSLSKFGIGLFETIRVKNGIAVDLDIHIERMLSSIN
                     CLDLDINYKKDFLINEIVTYIKKENVINKALRITVFDEGYNISIRDIPYNQETYEKGF
                     KLAISPIVRGNSLIHRHKTTNYFENIYTKNIANKTGYNDGIFLNSEGVILECSMSNIF
                     FIKGERVYTPSDRLPILNGIIKKRIIEICDELHIELIENEINISEISSFDFVFVTNSL
                     MGAIKVTEIDKIKFNKENVVFDKIVKLLE"
     gene            16393..17094
                     /locus_tag="PC494_001946"
     CDS             16393..17094
                     /locus_tag="PC494_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3912447.1"
                     /translation="MIGCIYEVYNEEMTKIIENQNTLAVYLVGSSKDVDFTLYDVVIN
                     DIDVFVFVKEGEKQERILFKKKGIEFDVNYFSKDGVKKLLSNREYFFVKEMKDAKVLF
                     DRENISHIIKDISRDIYLEGPSKMSLEEKSFIKQDIGAKILNLKNKEKFDVFEYHFLT
                     NLYLKDIIIGYFNINDKWVPKDKKLLKVLKKENNELFELVSKVSENYDYQRLLDVYNY
                     IFKEIETKEVIKLIF"
     gene            17120..17692
                     /gene="folE"
                     /locus_tag="PC494_001947"
     CDS             17120..17692
                     /gene="folE"
                     /locus_tag="PC494_001947"
                     /EC_number="3.5.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase I FolE"
                     /protein_id="HDF3912448.1"
                     /translation="MNKVDKEKIQHAVREILEAIGEDPDREGLIETPNRVARMYEEIF
                     SGLSEEPRDHLKVLFADEKHEELVLVKDIPFYSCCEHHLVPFFGKAHIAYLPKGGRLT
                     GLSKLARVIDTLAKRPQLQERITKNAADIIMEELQPYGVLVVVEAEHMCMTMRGVKKP
                     GSKTVTSAVRGIFEKDIASRAEAMSLITMK"
     gene            17756..18547
                     /gene="folP"
                     /locus_tag="PC494_001948"
     CDS             17756..18547
                     /gene="folP"
                     /locus_tag="PC494_001948"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HDF3912449.1"
                     /translation="MFDYGKRTYIMGILNVTPDSFSDGGDFNNLDIAIQHAKDMVDQG
                     ADIIDLGGESTRPGHSYVDSDEELRRVIPVIKKLKQELDIPISIDTYKADVAEEALKL
                     GVTMVNDVWGLRKDKNMASVIGKYDAEVCIMHNQDGTNYDKDIMESIKDFFKVSIEMA
                     MSCGVKKEKIVLDPGVGFGKDFEQNIEVLRRLNELKDLGYPILLGTSRKSVIGKVLPV
                     EPKKRLEGTIATTVLGIRDGVDIVRVHDVYENLMAARMTDAIYRK"
     gene            18558..18923
                     /gene="folB"
                     /locus_tag="PC494_001949"
     CDS             18558..18923
                     /gene="folB"
                     /locus_tag="PC494_001949"
                     /EC_number="4.1.2.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroneopterin aldolase"
                     /protein_id="HDF3912450.1"
                     /translation="MDKILLSNLGFYGYHGVLKEENFLGQKFFVDMELYIDSREAGLS
                     DDINKSVSYAEVYNVVKDITENKQFNLLEALAENIAEEVLNKFILINGVMVRVRKPEA
                     PVNGIYDYFGVEIRRTRDE"
     gene            18916..19422
                     /gene="folK"
                     /locus_tag="PC494_001950"
     CDS             18916..19422
                     /gene="folK"
                     /locus_tag="PC494_001950"
                     /EC_number="2.7.6.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-hydroxy-6-
                     hydroxymethyldihydropteridine diphosphokinase"
                     /protein_id="HDF3912451.1"
                     /translation="MNKAYLGIGTNMGDRFDNLSRACELLKNSDSIYKVKESSLYETK
                     PWGYTEQADFLNMCVEIETEFEPYELLEYCQEIERELHRERIVHWGPRTIDVDVLFFN
                     DVVSTDERLTIPHPRIQDRAFVLIPLMDLNEELIINEKTIKEHLNLLSAEEREEVKEL
                     VGYERKPI"
     gene            19403..20188
                     /gene="aroF"
                     /locus_tag="PC494_001951"
     CDS             19403..20188
                     /gene="aroF"
                     /locus_tag="PC494_001951"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HDF3912452.1"
                     /translation="MKENLFNNNSKIEINTNNKKITVKKDKLIIAGPCAIESYEQLLE
                     TAKFVKSQGANILRGGAYKPRTSPNSFQGLKKEGLEILKAVKDEVGMAVITELMDVRD
                     MDELYSISDIIQIGSRNMQNFTLLSEVGKQNKPVMLKRGIASTITEWIGASEYIAIEG
                     NSNIIMCERGIRTYNDYTRNTLDLAAVPIIQKETGLPVVVDPSHATGVRYLVKPMSLA
                     SFACGADGIMVEVHPDPENALSDGAQSLCFNEFEDLMKSINNY"
     gene            20443..22233
                     /locus_tag="PC494_001952"
     CDS             20443..22233
                     /locus_tag="PC494_001952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HDF3912453.1"
                     /translation="MNDIKDIIEEIKARCDIASIISEYMNIKQSGANYKGLCPFHGEK
                     TPSFYINTSKQIYKCFGCGEGGDVINFVMKMENLDFMDAVKILANKCGIEINTNMNEE
                     TRIKIEKSKKFQDIHTEAARFYLSNLLGSKNLGYEYLRIRGLDDKIIKKFGLGFSLDS
                     WNSLMNTLISKGYKKQDLLECGLIAKNRDGTNCYDKFRNRVMFPIFDYRGNIIGFGGR
                     VLDDSLPKYLNSPDTLIFNKKQNLYGLNFARKNLESKTIVLVEGYMDLISLYQYGIKN
                     VVATLGTALTEQQGILIKRYADTAIISYDSDEAGIKATLRAIDILTKLGINVKVLDLK
                     DAKDPDEFVRKYGLSDYKKAMDVSTHYIKYKIDHLKKEFNIQKDEERVKFAKEASKII
                     KQLTSPVEIDFYTKYLSNQIDINVESIKREVYGKNYNKPYNNKNQKKIEEKVIEKVEV
                     RQDGKQLVEETLIKIMLEDKKIREIALLKVEESDFLLKESKEILNYMIKNQELDKITI
                     DKLKSLNISEEYLKELNSISLNSINLENTKEIEGIITNIRKNSLEEQINSLLREQQEL
                     ENNNDMKEVDGRVMEIALKIVEINKILKSL"
     gene            22251..23417
                     /gene="rpoD"
                     /locus_tag="PC494_001953"
     CDS             22251..23417
                     /gene="rpoD"
                     /locus_tag="PC494_001953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HDF3912454.1"
                     /translation="MENKSNKKELKKVTAKTLIEKGKKQGSLTLAEIMEAFSETELDK
                     DQVENLYETLGNLGIEITETKNYKADIDFSVADDDLSIGHLDEDAEAISHDDSSAIEI
                     ETVDLSLPKGISIDDPVRMYLKEIGKIPLLKPHEEVEFARRMHEGDEIAKQRLVEANL
                     RLVVSIAKRYVGRGMLFLDLIQEGNLGLIKAVEKFDYTKGYKFSTYATWWIRQAITRA
                     IADQARTIRIPVHMVETINKLIRVSRQLLQELGRDPKPEEIAKEMEMTEDKVREIMKI
                     AQDPVSLETPIGEEEDSHLGDFIPDDDAPAPAEAAAYSLLKEQIEDVLGSLNDREQKV
                     LKLRFGLEDGRARTLEEVGKEFDVTRERIRQIEAKALRKLRHPSRSKKLRDYLD"
     gene            23582..24271
                     /locus_tag="PC494_001954"
     CDS             23582..24271
                     /locus_tag="PC494_001954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase"
                     /protein_id="HDF3912455.1"
                     /translation="MKLTDRLLKIASLVSDGKKIADIGTDHGYIPVYLLKEGKVPFAV
                     LADVNKGPLDNAHKEVIQNNLLDKVDLRLGSGIEILEIGEVEEVIIAGMGGILISELL
                     EAKKEVAHNVEKLILQPMQAQEELRYYLLNNGYEILEEVLVREDFRIYEIIVAKYTGK
                     NTIIEDEIYYEVGIKLLENKDSLFNDFIEKKIKTYSSIVNKLEGKNGEAIDKKRKESE
                     VAIKKLENLIK"
     gene            24285..25382
                     /locus_tag="PC494_001955"
     CDS             24285..25382
                     /locus_tag="PC494_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HDF3912456.1"
                     /translation="MLLKSLTRKIEKKYPLNLAEDWDNVGLIVGDFDMDVKKVLVSLE
                     ANEDVIDEAISKNIDLIVTHHPFIFGKINKINSGDLKGRLIQKLIKNDISLYSMHTNF
                     DIAFDGLNDYFMEIMEFGNSKVLDITKSENLYKLAVYVPHNYSDELRKVLSNSGAGHI
                     GNYSDCTFSIEGEGQFKPLEGSNPFLGSVNDIETVNEVKIETVVPQKLLGGVISSMLD
                     AHPYEEVAYDLYKLENKGEIFGLGRISKLDKSMTLESLSRKIKEKLNMKHIRVVGNLS
                     TDITKVAVVTGAGSEFVKKAKRQGAEVLITGDVKYHEAQDALDIGMCIVDCGHFDTED
                     IFKNVMKRFLDEFSEIEVIKSNVYLNPFSTI"
     gene            25445..26017
                     /locus_tag="PC494_001956"
     CDS             25445..26017
                     /locus_tag="PC494_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HDF3912457.1"
                     /translation="MKVAVIFHSVCGSTYLLAREYKEALEEMNIEVDIFRVSDEVAKT
                     LPQYYLINSKEYKDEFESINVIKSGKEILDYDAIFMGSPTYYGNVSGPMKMFMDSFSD
                     IWVGTPLSGKIFGCFATAGSQHGGGELALQAMNIFAQHMGMTLLSVPCSVRGGYPAYG
                     ILHIAGDNSDIRPNDDAKIGIRDYLKRLNI"
     gene            complement(26077..26544)
                     /locus_tag="PC494_001957"
     CDS             complement(26077..26544)
                     /locus_tag="PC494_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine 5'-phosphate oxidase family
                     protein"
                     /protein_id="HDF3912458.1"
                     /translation="MFKEMRLKKREMTKEDTVEVLKNGEFGTFSTISENGYPYGVAVN
                     YVYFNDSIYFHCARNGHKLDNISKNNKVSFLVVANESVIPDKFSTTYSSAIVFGKACT
                     VENEEKKNALVEIIKKYSKGFFEEGMKYIEKDMNLTTVVKIEIDHISGKASRL"
     gene            complement(26930..27406)
                     /locus_tag="PC494_001958"
     CDS             complement(26930..27406)
                     /locus_tag="PC494_001958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HDF3912459.1"
                     /translation="MLSKAEIKYFNECASEILSSEKVQLMRTFPHHGNVSCLEHSLSV
                     AYYSYLLCKKLHLSVDIQSVIRGALLHDFFLYDWHYKGDRKGLHGFTHPREALKNATL
                     FFQINEKETDIILKHMWPLTVKPPRYKEAFIVCLLDKFCCLVETLKIHSLLSPYHV"
     gene            complement(27526..28617)
                     /locus_tag="PC494_001959"
     CDS             complement(27526..28617)
                     /locus_tag="PC494_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1648 domain-containing protein"
                     /protein_id="HDF3912460.1"
                     /translation="MSKIECLFTIFPVLILMYATFYFMPYFVGKKHIYGVSIDQEHKN
                     YNYFIKLDKEFKKLLSLGFIIDFILVFILVFTFNKLELSYFIGIIGFLLYESILYIHT
                     HKKAKKLKSEIYSKLGHIDIDSKLIVDMDFINKKNKIIKKFKIIYLIPILFTLGMSIF
                     IAFNYNQLPDSIATHWNINGSPDVFIDKSFLNVFKLIGTDFCLMVLLYITSIGSIKSR
                     IKIDTNRIEESRVENIKYLNKIGYLFLILMIIMTTQFFTTLLSIKTKLSTAMNITTLL
                     VIIYLIATYINSPNLKFNSSYSPEEDEKYWIAGIMYNNPNDPSLMVNKRFGIGWTINF
                     GNPLGKILYIAIALLLIFSLFSLIKSLLL"
     gene            complement(28610..28999)
                     /locus_tag="PC494_001960"
     CDS             complement(28610..28999)
                     /locus_tag="PC494_001960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDF3912461.1"
                     /translation="MVLNLDFNSDKSIYVQIKEEITKAIASGELKINESLPSVRSMAE
                     NIGVNLHTVNKSYNELKEEGFLNIDRRKGAIVAQLPMKIDNTTRQKNKLDLELLVAKS
                     YLSGISKEEFLSLSSSLFDKYEVKYYE"
     gene            29191..29637
                     /locus_tag="PC494_001961"
     CDS             29191..29637
                     /locus_tag="PC494_001961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3912462.1"
                     /translation="MLTYLMKRQMHKKDDGMSKPMMITGAVITGVGAYAVYKMVKSHK
                     SNSQMVNTNYYGNSDYDDYKYDEFDYDCDCRDTKQDYEYEELKKKVKEFNSRRINCEN
                     CPHVSQEEMMQYVNSVKDVKEEIDLHEDAKKDNIYKEDEYKKYEEE"
     gene            29901..30626
                     /locus_tag="PC494_001962"
     CDS             29901..30626
                     /locus_tag="PC494_001962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF3912463.1"
                     /translation="MKRKEIVMLKLLIVEDDSTISFGIKYALEQEGFSIDISKDLSSG
                     KEMISSNEYSMILLDVTLPDGTGYELCQYIRGFSQVPIIFLTACDEEVNIVMGLDIGG
                     DDYITKPFRIRELISRIKAVLRRKGNTSEENKKILKFGDLSIYTLEARVYKNDKEIFL
                     TSVEYKLLLILIQNKNTVLSRTQILEKLWDVTYDFVNDNTLTVYIKRLREKIGDDLCE
                     PIYIETVRGIGYKWIGSENSVSI"
     gene            30613..31857
                     /locus_tag="PC494_001963"
     CDS             30613..31857
                     /locus_tag="PC494_001963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF3912464.1"
                     /translation="MFLYNPEVKKFLSKYVTLMFIVIIISIGFSIINVSLTKEMVVRN
                     NQAIIGTLSSKYPNLESQIVDIITQGKSMENIDYGQKILIKYNYDKSIRINSEPIISK
                     LVLETIKINIILVCIIFILIFVLVVRYFKSIYNDLSDMTKYVYYSSEGKPFDMKNKNQ
                     EGQIGLLKTELLKMTTILNEKVELLKREKIFLNNTISDISHQLKTPMTSLIMLNDLLY
                     NDVPYEVKIDFLNKIKNQLNRMDWLIKSMLKLSKVEAKVINFKKDKVKFSELIHRAML
                     SMKIPMEIKNQKLTIEGNDNVSYIGDIDWSVEALVNIIKNCVEHTPEFGNIIITYKEN
                     PLFSELIIKDEGEGIDKKDIPHVFKRFYRGRSSSKEDSVGIGLAMSKSIIESQNGDIY
                     VNSEKGQGTEFHIIFHKMYDSD"
     gene            31937..32614
                     /locus_tag="PC494_001964"
     CDS             31937..32614
                     /locus_tag="PC494_001964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003517588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF3912465.1"
                     /translation="MEILRVENLTKSYGKNETKVDAIKNVSLSVEKGTFIAITGPSGS
                     GKSTLLHLLGGVDRPTSGKVYINDVDIYNLKTKDLAIFRRRNIGLIYQFYNLIPVLNV
                     KENILLPAELDNRDIDREYFDDLMKTLGLIDREKHLPNQLSGGQQQRTSIGRALINRP
                     SIILADEPTGNLDSKNSKEILELLKLSVKKYNQTLIMITHDKNMALQADRIISIEDGI
                     IKSDEVM"
     gene            32615..>35156
                     /locus_tag="PC494_001965"
     CDS             32615..>35156
                     /locus_tag="PC494_001965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF3912466.1"
                     /translation="MNLYTLLTIRYLKQNKRRTIVTIIGIILSTALICGIGNIFESFM
                     DYQMRETIKNDGSFHVTFYDVNRKNVEYVTKSAEIEKHAFTKQLGYSKLENSENAILS
                     IKQYDKNAINGYKVSIKEGRFPAKEGEIVLSESIINLIDDKLKIGDKITLKVGDMFDS
                     SKKKIDSMTFHEGDYIANEKDRTFKVVGIIEKPGFERYNGIATAIAYFNPMNNYNDTI
                     NVSVAVRNPKDVYKISNKISKNIYSNKDKEAVSDMIKYNEHLLRLQGASKYSNINNSI
                     KSIIIAVTILVIICTIATVYNSFSISINERKKQFGILNSIGATSSQIKRLVFIEGIII
                     SLIGIPIGLISGTVAIDLLFKIINKYFTESVVTKMSLQIVYNPIITIVSIIIVLLTIF
                     ISILLPAISASNISHLNVIKNTGEYKVGKIKSSRLIKMIFKTEGVLAYKNIRRNRKKF
                     IITLFSLMVSIIIFISFSGFTLLLLRGEEIRNSQRKYDLYLTAKNTARSVEDTISELE
                     DIDGIKNFELATGQYVSIRVSENKINKSKEDLIRKYYQKYKIGDSYEYDFSNNELIFP
                     GDFAVKNKINNLVQGSFNKERAIEENGVILVRKSAFEENGKKGVVELTNYKVGDTVNC
                     EYLDENALSKKVKVKILAITDEERLGLGYQNMGLQFITYDEVAKNLNLKLSKSLIFID
                     SGGSIKTKKEIEALANKNNFNFYDESASNESEKQDLKVIKIFVYGFIVVISLVSVTNI
                     LNTVSTSINLRKRELAVIQSIGVTPKGFRKMIYLESFIYGILSLLFGIPISIGIILIM
                     NKLISGVIEFSPIIPWTAIVICIVSVFIITFIAGYIPMSKLNKENIIDN"
BASE COUNT        14308 a         3615 c         6068 g        11165 t
ORIGIN      
        1 attagataca acttatttaa tataataaaa tctgcttttt atataactat aaaattttcc
       61 tacattctat tagaattgcc cataaatacc ttcaagttct tcttttaata cttcagggtc
      121 atttatacca atagacatgg ttctagccag tatatttgct tggtcataag ttgatgtcca
      181 tgagaataca ccacctagac aatttctaag aacatattga gtttttaaga atattgataa
      241 agcatcatca tatgacattg caaaatctcc atccttaact aaatatggaa cttgagcagt
      301 attatcaaat ctatattcat atccattttt atttatataa tcccttctaa gctcatcata
      361 agttcttgtt atagtagcac ctaatcttcc ataaaatggt ataccaagaa ggattttttc
      421 agaaggcatt ccagcattct caagatttct taccattgca tcaacactat atcctggcaa
      481 agataagtct gaatcaaaaa gatttgcttg atgttttcta ccatttgggc ctgtttcacc
      541 tgctgtaaaa tcataactca taagattaaa ataatctatt ataggagcta ttttatctat
      601 ttcagcactt gaatttatat atcctctatc tcctgttcca gctacactaa gccatttatc
      661 atctcctata acatctctta tggcagttag taagagtgta aagttttctc tatcttgagg
      721 tcttgatgtt attccagatg cactacttcc aggatattcc cagtctatat ctattccatc
      781 taaagcatat tcatttatca tctgattgac ctgtcttgca aaattatatc tagatgtagg
      841 tgttaatgct gcatcagaga atccttcagc tccccaacct ccaatagcta caattacttt
      901 taagctaggt ttttcacctt taagagcaag taattgattt aaaaatctag gataaggaat
      961 aaacaaattt ccagactggt ctatctcagc aaaagcaaat ataactgcat ctaatagttg
     1021 agcatctaca ttagttggat ttccaagaac atattctgct acaattggat ttatatctgg
     1081 acagtttgca ttttcaacta ttggattgta tgggtctgtt atttgtggtc taactaattt
     1141 tttagaatct tttaaagttt tcatagctat ttttttagta tttttttcgc tagtataatc
     1201 gtagttttta taattatgtt tatagaaatc ttcataacta ctatcttctt tgttatagct
     1261 agaatttatt ttgtcacaag attcatcttt atcatagtta aaattcattt catcacaaga
     1321 cttatcttta aacttatctt gtttggagtt gtgaactttg ttagtatttt tagtatgttt
     1381 tttctcatga ttgcaatcat ctttaatatc agtcttgtgt tcttgtttac agtcaagagc
     1441 tttgttcagg tagtcatgat gttcatgttc acagttacat tcattttcaa tgtttttagt
     1501 atgttctttt ttccagctac aagtattatc aattttcttg ctcacttctt catcattata
     1561 attatctggt acaaaacata agtaccagtc catacatgaa tatttcttat tacaactgtt
     1621 aactctattt tttaattcct tatagttttt aggataaggt aaaatcactg gcattccagg
     1681 aaaccagttt gcaggagtaa ctatattatc tctatcacta gtctgaagtg catctactat
     1741 tctaagtatt tctggaatat ttcttcctgt agttagtgga taataaagaa tcgttcttag
     1801 aatttgatta ttatctataa taaatacaga gcgaacagtt gatgtatcac tcattggttt
     1861 tgatatcatg ccgtataact tggcaattct catatctcta tcttctataa taggaaatgg
     1921 aatttctaca cctgtaagta aagaaatatt atacatccaa gctaaatgtg aactgttact
     1981 atcaacactt agaccaatta gttctgtatt tcttttttta aattcgtcat aatatttagc
     2041 aaaacataaa aattctgtag tacaaactgg tgtaaaatca ccaggatgtg aaaataaaac
     2101 aatccaatta cccttatagt cagagagtct aataggacca tttgttgtat tggctttaaa
     2161 atcaggagcc tttgacccta aacttggcaa atttggcatg taaatcaccc ctcaataaat
     2221 tatcatttat tttattctat taattaatac atattagtgt tactatttta ttaaaagtta
     2281 agtaatcctt atgtcaaaaa aagatattta ttaaaaagat ttaatatttt cctaatataa
     2341 atgacaatag taattgctat ttttttacta atttggtata gtaatggata aggggtagtg
     2401 tcaattttag tgattatacg aggtgagtgg attgaaaaaa attctaagaa ttttagttat
     2461 ctccatgatg atatgttttg caatgacttt tgcattagtg ttaataaatt cagttatggg
     2521 agtacatata ggattggatt attacttttt gatgggaagt gtgcttacag tttgtttaac
     2581 aattggaatt gttttatgca atgctagaaa aatatttgat agcaaagcta tacacaagac
     2641 aagaacgaaa actgtcagta ataataaaaa acaaaagagt cattctaggg atataaaaag
     2701 aaagatatca taatttatgt aaaggaaata tttatgtata aaataatgat tgataggtaa
     2761 aataaaaaca cgatttaact tgtgttttta ttttttttca agaattatga tataataacc
     2821 aataagaaat ttagtttacc ataaaatata aagattatta aatggagagg gaactataat
     2881 gaattttaga gatttatttg agaaggctgt agattttatt gatgaaaaaa ggaaatctat
     2941 agttgcgatt tcattatcaa cattaggtgt aattgctttg ataatagtat ttttcttaag
     3001 tagtaacgag tttagtgtag gaaatgaagc taatgagttg ttaaagatta tagagaaaag
     3061 acagtattct atagctgttg attactacac aagtatagaa aaaaagtttt ctgattcaaa
     3121 aatggaaagg tttaataagt ctgtttctaa aaaaataaat aaattgctat taaatagtgg
     3181 tgataaatat ttagatggag acataagtca agaaagtttt attggattaa taaataccgt
     3241 gaaagaatta aacaaaataa gtatagatgt ggatgactta ttagctcaag ctgatagagt
     3301 tagagaaatg tataaagaag aaaatactac ttatgatatt gccattaact acataagtac
     3361 tgtttcaata ttaaatggta tgggtagtaa cctagatgta tacaaacaga atatagaaac
     3421 aatcaaagag tctagagatg tttatgactc agcagtaaaa gaccaaaaag catataagta
     3481 ttatgaagct attgaaaagt ataataaagt attaaaagaa gatgaaaagt attacagtat
     3541 ggctcaaaat gggaaagaac aatgtattga agaaatgtat gattactata taagtagagc
     3601 tgaagaggca aatacttctg gagattatga aagagcatta caatatattg agtatttaaa
     3661 agacgattat tcagatgatg aaaaggtaca gagtttagaa aaaaaatata aaaagaattt
     3721 atcattgtat actttaacat ctgatgacat tataaatgta atagctaaaa aaagtggcaa
     3781 agacaaggca aatctatcta taaattcact tccacaaatg ataaaaaata ataaatacta
     3841 ttatgctgaa gtatatgagt atgataaatt aataaatgaa gttttggtaa gtgcaaaaac
     3901 taaagattta tattcatata aagatggtaa aaaagattac aaagtagatt atggtgatgg
     3961 atactttaga atattagaag atggaagtta tcaatttggt attacaaaag ataaagctaa
     4021 gtttgtgtta actaatactc ttgatgaaaa agaaaataag tataaaaaga ttgagatatt
     4081 agatatagag aaagcagata gatatgtaaa aagtaaaaag agtttagaag aattgtttgg
     4141 aaaatataaa aatatttatt attatgctgt agtaaataaa ggcttattta gaggcaaaga
     4201 agtttatgct attaatattt acaatgaaaa aatatatgcc atatcagaaa atggactaaa
     4261 tgaatattaa ttaataatat taaattaata tataattaaa aagtttttgg ggttttaagg
     4321 cgcattatgt agtaatataa taatagggat atataaataa ttttattgta aggagaagta
     4381 tgggatgagt aatgtgaaca aaaagctagt tatagctatt ggagctgtag cattagtagt
     4441 aataattttt ataggcataa tgtgcatgca atttaaaggg gagaaaatag caaaaaacac
     4501 atatgttaat ggagtaaata ttggaaaatt aactaaatca caagcaaaac aggaattagc
     4561 taaaaaatac aaattagaga atgttgattt taattacaat gataaaagct ggaaagtaaa
     4621 gagcaaagat ttaaatttat ctactgacct ggataaaaca gtagaaaacg catataattt
     4681 aaatagaaag agtgctttct ttggcaatct atcaaaaact atttcagcaa attttggcaa
     4741 aaaaagcaac ttagtagttg cgataaatta tgataaaaat aaattaaaag cagaaatgga
     4801 aaagatagct aaagaaatag atgtagatgt aaaagatgct acacttgata taagtggtga
     4861 aaaagtcaag gttataccag attctgatgg tcttaaaatg gatatttcta agagtatgga
     4921 gaattttgat aatcaaacta aaaaaggtaa ctataaaaat gagttagtag taaaagctac
     4981 tccagcaaaa gtaaaaaaag agcaacttgc taatatagat acaaatttag gtacgtattc
     5041 aacaacattt aaaacttctc aaataaatag aagtataaac ataaaattag caacagataa
     5101 tataagtaat gtattactta tgccaggaga aactttctca tttaataaac atacagggaa
     5161 aagaagtaag gaaaatggat ataaaagtgc acctgtaata atggaaggtg agatggaaga
     5221 agattatggt ggaggagttt gtcaagtttc atctacgtta tacaattctg tgctatacgc
     5281 aggtttagaa attgttaatg taaaaaatca tactatacca tcaagttatg ttccaaaagg
     5341 aagagatgca actgttgcag atagtggaat agatttctta tttaaaaata atctaaagca
     5401 tccagtttac ataaaaaatt acgtttcagg aaatcaaatt gtttgcaata tatatggaag
     5461 tgcagaagat aaacaaaata taacaatatc aacaaaatta gatggcgttt cacaaactac
     5521 aatgaaaaga gttaatgacc ctacaatgcc taaaggtaaa gaaaaagtag acaaaagtgg
     5581 aagaaatgca tattctgtat caacatatag aacatttaat gatgcaaatg gtaaaaaaat
     5641 taaaactgaa aaaatagcta attcatatta tcctaagaag gaaggtatta tattagttgg
     5701 gactatggaa ccaaaaccag aggaaaaacc aaatacagac gaaaataaga ataatcaaaa
     5761 tacaaacaat caaaacccaa ataatcaaca aaaaccagaa acaccaccaa ctgataataa
     5821 gcctaatgag acacaaccac aaccgcaagc ttaaagttct caagaatagg atttatgtag
     5881 agtaataaaa aatataaatc taaataggag ggattacttt gaatttaaat aatataacga
     5941 attacgttca aagtatttgc gagaatattt ctaatgtctt ggatgtagat gttactttag
     6001 ttacaaaaga tttaactagg atagcaggta caggaatatt cagaggtaaa ataggagaga
     6061 caatatcaga gaagtcagtg tactctcttg ttttaaaaga tgggaaatcc tatgttataa
     6121 ataaagaaat agaagagaac tgtaataaat gtgcaaatag agaaaattgt aaagagttag
     6181 ctgatatatg tactcccgtt aaaatgggag agcatatact tggaatcttg ggtatagctg
     6241 cgtttaatga agaacaaaaa gaaaagatac tttcaaaaga taaggagtta actgcttttg
     6301 taaggagtat gtctgattta atatctttta aactagatga actttataaa caagaagtta
     6361 agactataga tgaccttgag agggaagcta tagaaaatgc cataaagaaa tatggaagta
     6421 atacagaagg tatgaaaaaa gtagctgagg cattaaatat aggtatagct acactctata
     6481 gaaaagtaaa aaaattcaac attaaaagtt aatagtattg aaaaagaggt aaccttttta
     6541 tgaaaagaag aggattacct tttttattat gagaatggtg gaaaaatatg tatagttttg
     6601 acttgacata ttaaatatgt tatcttaaat atatatttta gagtggaggt gagtattatt
     6661 ttagttaaag atataaaaca agacatagaa agcatgccta gaaaaatttt agatatatct
     6721 ttgatagaag ataataaaag tgatttgact ttttttaata tagaagaaga agacggtgat
     6781 gaaacattaa aagcattaaa acagagttat gtgactacaa attataaaga agaaactcta
     6841 ttaaacttgc aaggagcttt aaattcaaag tcagatacaa cgtctaagga gttaaaatta
     6901 gaatcatata aaagatataa caatgcattg gatttagcat ataaaaatta tataactagt
     6961 gccattaata tggttaataa agctctggag ataaatccta aagacattga tatactaaat
     7021 cttagaggtc ttttaaaatt attaaaatgt gattttgcta aatcatttga gagtttttat
     7081 actgctttat gttatgaaaa taatcatata tctagaaaat atgtaaatct aatttcatct
     7141 gaagatttta aaactttttt aggaagatac aatcattcta taagatttat aaatgaagaa
     7201 ttaaattatg agtcaataca tattttagag aacataattg aagaagaacc tgaactaata
     7261 gagccatatg taattttatc tttgttatat gataaactag gtaatgtaaa aaagagagaa
     7321 ggatatttag acaaacttaa agagctagat aaagataatc ctgtatttga aaaaaatgaa
     7381 gaagaaaaag aagatacaag taaaaaggaa gaaataaaaa aagtaaaaag aaagaaaagt
     7441 attttgccat atattatagt tggctgtgtt ttaataggta tggggatata tttgattcaa
     7501 agcaaaaaga gaatagaaaa cttgaataac caaataagta gtaaagagga aaagttaagt
     7561 gaaactgata aaaagttagg agaaacgagt aaaaaattag aaaaaacgaa taaggaatta
     7621 aatgaggtta aaaataaaga accagaaaga gagataactg tagctgatga ggaagattta
     7681 tattatcaag ctctaaattt aaagaaaaac aaagaatatg aaaaagccat agataatttt
     7741 aaaagtgtag tttcttctgg taaaactaaa aaatatattt ctgagtcaat atatcaatta
     7801 gcaataacaa ataaattatt aggaaataag gatgaagcta taaaatatta caaaaaatat
     7861 ataaatactt atactaaaaa tgaccagtat tatgatgatt catattacga gttgggtatg
     7921 ctttattatg ataatggcga tttaaaaaat gcacaacaga ctttttatag tttgagaagt
     7981 gaagttccag acagtatgta taacaattca aaaataaaag aaattttaag tgaaaaatag
     8041 gtttatatag ttaagttttt tgaaacaacc aagtatgtat tttattaaat taaaataaaa
     8101 ataaatttaa aaagagattg tgtcaaatta taactttcta ttttaaagaa agatatttgc
     8161 ttgttgataa aactacaaat atatgatttg aagcaatctc tttaattttt ggaggtggaa
     8221 aatgaaagtt ttcaatcaat tggtaataat tttatctatc tgggtaatag gagagtatat
     8281 aagttccttt atacaaggaa ttatacttat tcctgggagt atagttggta tgctattatt
     8341 atttctacta ctacaattta aagttttaga cttgagtagt atagaaaatg taagtggatt
     8401 tttcctcgat aatatggcta tattttttat tccagcaggt gtatcactta taaagtcatt
     8461 agacctaata agggaaaatg tattagtgct tttattagtc atatgtttaa gtacactaat
     8521 agtaatgtat actactggaa ttattgtgga gaaaatgata aaaaagaagg aagaaggaca
     8581 aaaaaatgta taatgtatta cagacaccag tatttggtat aatagtaaca atagtttttt
     8641 tcaatttagg aagatacatt caacgaaaaa caagtaatcc tatatgtaac cctttattaa
     8701 ttgcaatcgt aggaataata ttgtttttaa gcatatctaa aatcccttat gagaattaca
     8761 agataggagc tgatagtcta aatttctttt taggtcctgt cacagtagta cttgcagttc
     8821 cactttataa acaatttgaa ttatttaaaa agcatatgtt tgagattatt gtaggaatag
     8881 gttgtggtat agtgatttct tttgtatctg tattgataat tggcaaaata gctaattcag
     8941 atgtaagtat aataaattca ctaattccaa aatctataac aacaccaatg ggaatatctt
     9001 tagcaaattc tttaaatggt gtagaatcaa taacagttgt agccataatt tttacaggta
     9061 tttttggtgg tatggttgct tctacagtat tcaaactggg gaatataaat catccagttg
     9121 ctaaaggaat tgctcttgga acatctgcac atgctttagg aactacaaag gcttttgaac
     9181 ttggagaaat agaaggagct atgagtggtg tttctattgg agtctctggt acaattacag
     9241 taatactaat tccaattata atgaatttta tataaaaaat aaaattaaga tgagtacctt
     9301 gaatacttaa aacaaaataa aataaaaaaa atttaaaata aaaactgaac gaaaaaaatg
     9361 caaataatga aataaaaaaa tcatgtactg aaattataaa aagaaaaatt tcatttagga
     9421 attaattata aagagacaat tactaaactt gaatttgcta aaataaaata aattactgct
     9481 aaaatagata tttagaaaaa aatactataa atttactata ttgcaagtta aataataagc
     9541 agtatcatat tatgctagaa aaagtttcat ttaaggcata aatgagatga tttgaacgtt
     9601 tttaaagatt agaatataaa agattgcact agacatatat gaaaaagata atataataga
     9661 tgatgtaata gatgacagtt caagaaatta taaaaaaaat ttatttgaaa tattatctat
     9721 tacatcagga ataatatatg taagagtaag cttttaaaat tctaaagatt tagaaagatt
     9781 gaagggagaa agaaatgagt gaagttaaga ataccctaca aaaacatcca gttttaagat
     9841 attcaacaat gctatttggg atgttgatga catctatagg aataaatggg ttcttaagac
     9901 cagcacatct gcttagtgga ggtgctacag gtatagcaac atctataaac tatttgacaa
     9961 atataaatgt aggtttatta acatttttaa tcaatattcc aatatttatc ttagggttca
    10021 tataccttga aaaagagttt tgtatttcaa gtttggtaaa tatgattgta ttttcattat
    10081 tattaggagc aactcaggaa ataagtaata ttatacctat acatgatata ttgcttcaaa
    10141 gtgtatatgg tggtatatta tctggtttag gagtcggagt tgtatttaga actaggtctt
    10201 ctcaaggtgg tacagatata atagctgcaa tactaaaaat taagaagaat atagaaatga
    10261 aagacactgc tttagcaata aatggcttga tagtacttac aggaagtttt ttatttgggt
    10321 tggatttagc attatacact cttataggtc tatttctaaa tgcgtattca atgagtttta
    10381 ttaaagatgc aatgaattac caaaaatctg ttatggtaat gtcaaatgaa gtcgatttaa
    10441 tagcagaaga tataatgaag agtttagtta gaggtgtaac ttttttagat gcagaaggtg
    10501 catacactca tcaaaaaaag aagattatat atacaatagt ttcatcaaat gagataccaa
    10561 agataaaaga tatagctttg aagtatgata aaaaggcctt tatatctgta aatgatgtta
    10621 cagaagtaaa gggaagaggg tttaaagcaa aagatttata gaaaatttta caagctggga
    10681 gtttataatg taaatttgta tattatatct ctcagcttat ttaaatttag tatacgaaaa
    10741 taaaggtttt attaatgatt tgtgtatcac tttaaaagat atcattttaa aattaaaatt
    10801 gaaaaaatta cttaatatgt agaaaacatg accactatta ggatataata aatttaatag
    10861 atttagtaaa atacctagga ataacgttgg aggaatggca ttatgaattt atctaaagaa
    10921 tatgttaatt tgtatgataa ttatttgaaa tatataaatg aagtaaacaa agagattaga
    10981 agtataaaga acatgaagaa acgtgtttta aaaaggggcg attttgctcc ggaaaatgaa
    11041 gtattagaat tggaaggaaa aacaatacgc gatatagatg atgtcgatac aaaaaaacca
    11101 aaaaataaaa tctataaatt ttcaaatggg gatgtatatg tagggaaatt cttagaggga
    11161 aagatggagg ggaaaggctc atatactttt tttgtagatg aaggaacagt tatggagtac
    11221 ataggagaat ttaaagaaga taaaaaaaat ggaaaaggaa actttatatt ttcaaatgga
    11281 aatgaatata taggttattt tgaggaagat atgatgagcg gtattggaaa tatgttatat
    11341 agtagtaaag atgaatatat tggaacttgg aaaaacggaa aaaaagatgg aaaaggtatt
    11401 tataagtgga gtgatggatg tatatatgca ggtgaattta aaggtggaaa gatggaaggg
    11461 tacggtattt gctataatag taaaggggaa gtactttatg aaggagaatg gaagaataat
    11521 ttgattcatg gtaagggaac ttatatatgg gaaaaaggta aaaagtatat aggtgaattt
    11581 atgcatggta aaaaacatgg gcaaggaact ttttatctaa ataatgaatt ggtttatgaa
    11641 gggacttgga aatttgataa gccatctata tttgatagaa cattagatga aatattttcc
    11701 ttgagactgt agctttatct aattagtaga taaagctttt ttctaatact tactgtaaat
    11761 aggtatgaat gatattgatt agtatacact atcaatatta acttaataaa tgcaatatta
    11821 aaaaattttg attgatttta agaaggagag atatattgaa gagattaatt gctttagtgt
    11881 tagtagtact tattgtttta ttttatagtc ctgaattatt aaaagaagga tatgatttaa
    11941 aagaaaagtt ttttcaaagt gaaatatgga atgaattttt agacaaaata aatataaatg
    12001 ataattctaa gaaagataaa aaagaaaaaa gtcaaaattt acaatcaaat aatactgaag
    12061 gggagaactt aggagagtca gatataaaga attttgaaaa aataagctta ggagataatt
    12121 taagctatgt tttatcaagt atcggcaaac ctggtagaat tgatattagt gaatatggtt
    12181 ttgattggta tgtatataat caatatggaa aagaatttgc aatggttgga cttgaaaatg
    12241 atgaagtagt agcactttat agtaattcta ttaattcatg tgaaaatcaa gatataaaac
    12301 taaatcaaga tagacaaaca gtgagaacta agattacacc attaaaatat aagagaaaag
    12361 gaaataccag atatataata aactcagaaa atcaatatga tataataagt aaggaaggta
    12421 agtatattac aattttctac gatattcatg aagaaaatag agtttgttca tatttaataa
    12481 ttgataaaag cactgaagat gagtttaaaa atttatatcc agatgatagc gaagaactta
    12541 aaaaatgttt tgaacttgaa gttatagacc ttgtaaatag tgttagaaat caaagagggt
    12601 taaactcatt gagatacagt gaacaggcaa ctttgagttc aagaaaacat agtgaagata
    12661 tgagagataa taattttttt gaccatgtaa ataagaagaa tgaaactcca tttgacagaa
    12721 tgaaaagaga aggtatagta tatacttcag ctggagaaaa catagcagca ggacagatta
    12781 atgcaatata tgcgcatgaa gcttggatga actctgaagg acatagaaaa aatattttgg
    12841 ggaactataa taatattgga gttggagtaa tatttggagg aagctataaa acatattaca
    12901 ctcaaaattt ttataaataa ctaaaatatt tgaaaggaag ttaaaaaatg acatcatgga
    12961 aaaaaaagac agtatataag tgcttaatag cagtagcctt gttttgtgga atagtgttaa
    13021 tatctaattt tagtaaagtt tctgctttga tgatggatac taatggaaat gttttgatta
    13081 aacatggttc aagggaaaaa aagctaatag caattacctt tgatgatggt cctcatccta
    13141 aagaaactag tcaagtttta gatgtattaa agaaatacaa tgtaaaagct acttttttta
    13201 tagctggaaa acatgcaaaa tggtataaag aaccattagt aagagcaagt aaagaaggtc
    13261 acgagatagg aaatcatact ttcaatcatc ctgatataag taatttaagt tctagtcaga
    13321 tagaagagga gattgttaag tgtgaagaca ttttgaagga agtaactggg aaaaaaccta
    13381 cattatttag accaccattc ggaagttata gagaaaaaga cttaatagaa attgcaaaaa
    13441 agcatgacta taaagttgtt ttatggacag gtgtagatgt gaaagattgg aaaaatccag
    13501 gagctaatag cattgcagat aaaataatta ataaagtaca aaatggagat ataatacttt
    13561 tgcatgatta tgcaactaat gatacagttg aagctttaga tatgtttatt ccaaaaatga
    13621 ttgaaaaagg ttttaaattt gtaacagttt ctgagttgat aaaataattt ttagggggga
    13681 gatttacagt atgattctta tgatagacaa ttatgattct tttgtataca acctagtcca
    13741 atatatagaa gaattagggg aagcagttgt agtaaaaaga aataatgaaa tcaaaataag
    13801 tgacattgaa gaactaaatc cagaggtaat tgtgttatct ccaggaccgt gttctccaaa
    13861 agaagctggt atttgcatag atattgttga gcattttaag gggaaaaaac ctatactagg
    13921 aatttgttta ggtcaccaaa ctattggaca tgtttttgga ggagatatta taaaagcaca
    13981 acagcctgtg catggaaaag tatatagtat caaccatact aataaaggag tttttagggg
    14041 acttaaaaat cctttaaatg tcactaggta tcattcacta atagttgact ccaatacagt
    14101 tccaaaagaa ttagaaatta cagcaattac tgataaaggg gaaataatgg gaattaggca
    14161 taagaaatat ttaatagaag gagtacagtt tcatccagaa gctattttgt cagagtatgg
    14221 tcatgaaatg cttaaaaatt ttataacaga agctagagaa agggtacata tgtaatatga
    14281 taagagagat aaatactaaa ttaaattctt ttgagatatt tactattttt agaaatgaac
    14341 atgacagttt tatattagat agtgctatgg ataaagaaaa attgggaaga tattctttta
    14401 taagtagcca accatttaag gtattaaagt ataaagatac tgatgaaaat cctttagaag
    14461 ttttaaaaga agaactacat aagtataggg ttgtaaatga tactaatctt ccatttgtag
    14521 gaggtgctgt gggatattta tcttatgatt taggtaatta catagaaaat ttacctagaa
    14581 ctgctgtaga tgatattgag atgcctgata tgtattttgg attttataat catgtaatag
    14641 ttatagacca tcttgtgcaa aaaacttata tagctactcc aaacatagat atcgaattag
    14701 aagaaaagat aatagatgat atagaacaaa gaatattaaa agaagagaaa aaaggtatag
    14761 atagcatatg ttatgaagaa aaagaagtaa cacctataag acttaaatct aattttacaa
    14821 aggaagaatt taaaaatgca gttcaaagtg ttagagagta cataagacaa ggagatatat
    14881 atcaagctaa tttaacacaa aggttcagtg gagaaacaga acttacaagc tttgaattgt
    14941 atagggactt aagaagattt agcccagcac catttggggc attcttaaac tttgaagatg
    15001 cacatatatt atcaaattct ccagaaagat ttataagatg tgttaataag agaatagaaa
    15061 ctagaccaat aaaaggtact cgtccaagag ggaaagataa agaagaagat ttaagacttc
    15121 aacaagaact tagaaatagt gaaaaagata gagctgaact acttatgata gtagatttag
    15181 aaagaaatga tattgggaga atatctaaaa ctggaagtgt taaagttcca gagctatttg
    15241 taattgaacc atatgcaaat gtaaatcact tagtttccac agttgtaggt gagttaaaag
    15301 atgataaaga tgctactgat gtaataaaag caacttttcc aggggggtct ataacaggag
    15361 cacctaagat tagagcaatg gaaattatag acgaattaga gccaacgcaa agaaatgtat
    15421 atactggttc aataggttat ataggtttta atggtgatat ggattttaat atagcaatta
    15481 gaacaataat caaaaatgac aaaaaagtct actttcaagt tggaggagga atgacttggg
    15541 attctgaccc agatgaagaa tatcaagaaa cacttgataa agctaaatcc ataatgaagg
    15601 ctttgagggg atattatgaa gaataatgta ggttttgata gtagtttaag taaatttgga
    15661 attggtttgt ttgaaactat tagagttaaa aatggaatag cagtagattt agatatccat
    15721 atagaaagaa tgctaagctc aataaattgt ttggatttag atataaacta taaaaaagat
    15781 ttcttgataa atgaaattgt tacatatata aaaaaagaaa atgtcattaa taaagcactt
    15841 agaattactg tttttgatga aggttataat atatctatta gggatattcc atataatcaa
    15901 gagacgtatg agaaggggtt taaattagct atatctccaa tagttagggg gaatagttta
    15961 attcatagac ataagactac taattatttt gaaaacatat ataccaaaaa tatcgcaaat
    16021 aagactggtt ataatgatgg tatattttta aattcagaag gtgtaatatt agaatgttct
    16081 atgagcaata ttttctttat aaaaggagaa agagtgtaca ctcctagtga tagattaccg
    16141 atattaaatg gaataataaa aaaaaggatt atagagattt gtgacgaatt acatatagag
    16201 ttgatagaaa atgaaattaa tatatcagaa attagtagtt ttgattttgt ttttgtcaca
    16261 aatagtctta tgggcgctat aaaggttaca gaaattgaca aaataaaatt taataaagaa
    16321 aatgttgttt ttgataaaat agtgaagtta ttagaataaa ttaaaatatt aacaatttgt
    16381 tggagacaaa agatgatagg ttgtatttat gaagtataca atgaagagat gactaaaata
    16441 atagaaaacc aaaacacttt ggctgtatat ttagtgggtt ctagtaaaga tgtagatttt
    16501 actctttatg atgtagtgat aaacgatatt gatgtgttcg tttttgtaaa agaaggggaa
    16561 aaacaagaga gaatactgtt taaaaaaaag ggaatagaat ttgatgtaaa ttacttttca
    16621 aaagatggtg taaaaaaatt attatcaaat agggaatatt tctttgtgaa agaaatgaaa
    16681 gatgctaaag tactgtttga tagggagaat atatcacata ttataaaaga tataagtaga
    16741 gatatttact tagaaggacc tagtaaaatg tcattagagg aaaagtcttt tataaagcaa
    16801 gatattggag caaaaatatt gaatttaaaa aataaagaaa aatttgatgt ttttgaatat
    16861 cattttttga cgaatttata tttaaaagat ataataattg ggtactttaa tataaatgat
    16921 aaatgggtac caaaagacaa aaaattgcta aaagttttaa aaaaagaaaa taatgagctt
    16981 tttgaactag tgtcaaaagt aagtgaaaat tatgactatc aaagactttt agatgtttat
    17041 aattatattt ttaaagaaat tgagacaaaa gaggttataa aactaatctt ctagtcacaa
    17101 atcaatgggg ggagtttaaa tgaataaagt tgataaagaa aagatacaac atgcagtaag
    17161 agaaatacta gaggcaattg gggaagaccc agatagagaa ggtctaatcg aaactccaaa
    17221 tagagttgct aggatgtatg aagagatatt ctctggtctt agtgaagaac caagagacca
    17281 tttaaaagtt ctttttgcag atgaaaaaca tgaagagtta gtattggtaa aagatattcc
    17341 attttattca tgttgtgagc atcatctagt tcctttcttt ggaaaagctc atattgctta
    17401 tttaccaaaa ggaggaagac ttacagggct ttctaaactt gctagagtaa tagatacatt
    17461 ggcaaaaaga ccacaattac aagaaagaat cactaaaaat gctgcagata taataatgga
    17521 agaattacaa ccttatggtg tcttagtagt agtagaagct gaacatatgt gcatgacaat
    17581 gagaggcgta aaaaaaccag gttcaaaaac tgttacatca gcagtgagag gaatatttga
    17641 aaaggacatt gcgtctagag ccgaggctat gagtttgatt actatgaagt agtaatttat
    17701 tatagatata atcatttatt gagataaaat ttaatttaag ggagtgtcat taattgtgtt
    17761 tgattatggt aaaagaactt atataatggg aatattaaat gtaactccag atagtttttc
    17821 tgatggagga gattttaata acttggacat agcaatacaa catgcaaaag atatggttga
    17881 ccaaggtgca gatataatag acctaggagg agagtctaca cgcccaggtc atagctatgt
    17941 agactcagac gaagagctaa gaagagtaat ccctgtaata aaaaaactta aacaggaatt
    18001 ggatatacca atatcaatag acacttataa ggcagatgtt gcagaagaag cattaaaatt
    18061 aggtgtcact atggtaaatg atgtttgggg tcttagaaaa gataaaaata tggcttctgt
    18121 aataggaaaa tatgatgcag aagtgtgtat aatgcataat caagatggga caaactatga
    18181 caaagatata atggagtcaa taaaagactt ttttaaggta agtatagaaa tggcaatgag
    18241 ttgtggtgta aaaaaagaaa aaatagtact tgacccaggt gtaggatttg gcaaggattt
    18301 tgaacaaaat attgaagtat tgagaagatt aaatgaatta aaagatttag ggtatcctat
    18361 tttgcttggg acatccagaa aatcagtaat aggaaaagta cttccagttg agcctaaaaa
    18421 aagattagaa ggtacaatag ctactactgt tcttggtata agagatggcg tagatatagt
    18481 tagagtacat gatgtttatg aaaatttaat ggcagctaga atgactgatg caatatatag
    18541 aaagtaggta taatataatg gataaaatat tacttagtaa tctaggattc tatggatatc
    18601 atggtgttct taaagaagaa aattttctag gtcagaaatt ctttgtcgac atggaacttt
    18661 atattgattc aagagaagca ggtcttagtg acgatataaa taaatctgta agctatgccg
    18721 aggtttacaa tgttgttaaa gatattactg aaaataaaca atttaatctt ttggaggctt
    18781 tagcggaaaa tattgctgaa gaagtcttga ataaatttat acttataaat ggagttatgg
    18841 tcagagttag aaagcctgag gctcctgtaa atggtattta tgactatttt ggtgttgaga
    18901 taaggagaac aagagatgaa taaggcttat ttgggaatag gtactaacat gggtgataga
    18961 tttgataatt tatcaagagc atgtgaactt ttgaaaaata gtgattctat atataaagta
    19021 aaagaatcaa gcttatacga aacaaaacca tggggatata cagaacaagc agattttcta
    19081 aatatgtgtg tagaaataga aacagagttt gaaccttatg agttgttaga atattgtcaa
    19141 gaaatagaga gagaactaca cagagagaga atagttcatt ggggaccaag aactatagat
    19201 gtagacgtac tattttttaa tgatgtagtt tccactgatg aaagactaac aatacctcat
    19261 ccaaggattc aagatagagc tttcgttttg ataccactta tggatttaaa tgaagaactt
    19321 ataataaatg aaaaaacaat aaaagaacat ttaaacctcc tatctgctga agaaagagaa
    19381 gaagtaaagg agcttgtagg ttatgaaaga aaacctattt aataataatt caaagataga
    19441 gataaataca aataacaaaa agataactgt aaaaaaagat aaacttataa tagctggacc
    19501 atgtgcaata gagagttatg agcaactttt ggagactgct aaatttgtaa aaagtcaggg
    19561 agcaaatatt ttaagaggtg gagcatacaa gccaagaaca tctccaaatt catttcaagg
    19621 attaaaaaaa gaaggtcttg aaatattaaa agcggttaaa gacgaagttg gtatggctgt
    19681 tattacagaa cttatggatg taagagatat ggacgaactg tatagtataa gtgatataat
    19741 tcaaattggg tcaagaaata tgcaaaactt tactctttta agtgaagtgg gaaaacaaaa
    19801 taaacctgtt atgttaaaaa gaggaatagc ttccacaatt actgaatgga taggtgcttc
    19861 tgaatatata gcaatagaag gaaatagtaa tattataatg tgtgagagag gtataagaac
    19921 gtataatgat tatactagaa atacattaga tttagctgca gtacccatta ttcaaaagga
    19981 aacaggtctt cctgttgtgg tagacccaag ccatgccact ggagttagat atttggtaaa
    20041 acctatgtca ctggcatctt ttgcatgtgg agcagatgga ataatggtag aagtacatcc
    20101 tgacccagaa aatgctttgt cagatggtgc tcaatctctt tgctttaatg aatttgaaga
    20161 tttaatgaaa tcaattaata attattaaaa gaggcaagag cctctttttt attcgtaatc
    20221 gttgctaagg taaatttata agttataatt tgatagttag attatttaat ataaataaag
    20281 atttaatatt gatagaatta atataaaaaa taaaaatttt ttgattaata agaaggatat
    20341 caataaaaaa agtcgaattg tgtatattga gtgattgaca aatttagaat atagtgtaga
    20401 atagaaatgt taacacaaaa aattacacca gaaggtgata atatgaatga tataaaagac
    20461 attattgaag aaataaaagc tagatgcgat atagcaagta taatatctga atatatgaat
    20521 ataaaacaat ctggagctaa ttacaaagga ttatgtccat ttcatggcga aaagacacct
    20581 tctttttata taaatacgtc aaaacagatt tataagtgtt ttggttgtgg tgaaggtgga
    20641 gacgtaataa attttgtcat gaaaatggaa aatttggatt ttatggatgc tgtaaaaatt
    20701 ttagcaaata aatgcggtat agaaattaac actaacatga atgaagaaac taggattaaa
    20761 atagaaaaat ctaagaaatt tcaagatatt catacggaag cagctagatt ttatctttca
    20821 aacttattgg gaagcaaaaa tcttgggtat gaatatttaa gaataagagg actagatgat
    20881 aaaattatta agaaatttgg tttaggattt tctttggatt catggaattc acttatgaat
    20941 actctaatca gtaaaggata taaaaaacaa gacttattgg agtgcggtct aattgcaaaa
    21001 aatagagatg gaactaattg ctatgataaa tttagaaata gagttatgtt tcctatattc
    21061 gattatagag gaaatataat aggatttggg ggaagagtat tagacgattc tttgccaaaa
    21121 tacttaaatt ctccagacac gttaattttt aataaaaaac agaacttata cggattaaat
    21181 tttgctagaa aaaatttaga aagtaaaact atagtcttag ttgaaggata tatggattta
    21241 atttcgcttt atcagtatgg tataaaaaat gtagtagcaa cccttggaac agccttgact
    21301 gaacaacaag gcattttaat aaagagatat gcggacactg ctattatatc ttatgattct
    21361 gatgaagcag gaataaaagc gactttaaga gctatagata tacttactaa attaggtatc
    21421 aatgtaaaag tgttagactt aaaagatgct aaagacccag atgaatttgt aagaaaatac
    21481 ggacttagtg attataaaaa agctatggat gtttctactc actacataaa atataaaata
    21541 gatcatctta aaaaagaatt taacattcaa aaagatgaag aacgagtgaa gttcgcaaaa
    21601 gaagcttcta aaattataaa acaattgaca agtcctgttg aaattgattt ttatacaaag
    21661 tatttaagca atcaaataga tattaatgtc gagtctataa agagagaagt ttatggtaaa
    21721 aattacaata agccatataa taacaaaaat caaaagaaaa tagaagaaaa agtaattgaa
    21781 aaagtcgaag tcagacaaga cggaaaacaa ttagttgaag aaactctaat aaaaataatg
    21841 ttagaagaca aaaaaattag agaaatagcg ttacttaaag tagaagaaag tgatttttta
    21901 ttgaaagaaa gtaaagaaat tttaaattac atgattaaaa atcaagaatt ggacaaaata
    21961 actattgaca aattgaaaag tttaaacata tccgaagaat acttaaaaga attaaattca
    22021 atttctttga atagtataaa cttagagaac acaaaagaaa tagaaggaat aataacaaat
    22081 atcagaaaaa actcattaga agagcaaatt aatagcttgt tgagagaaca acaagaatta
    22141 gaaaataata atgatatgaa agaggtagat ggtagagtta tggaaattgc tttaaaaata
    22201 gttgagataa ataaaatttt aaagagcttg tagagaaagg aggtttgagt gtggaaaata
    22261 aatcgaataa aaaagagtta aaaaaggtta ctgctaagac attaatagaa aaaggaaaaa
    22321 agcaaggttc tctgacactt gcagagataa tggaagcttt ttcggagact gaacttgata
    22381 aggatcaagt agaaaatctt tatgagactt taggaaattt gggaatagaa ataacagaaa
    22441 caaaaaacta taaagctgat atagattttt cggttgctga tgacgattta agtataggcc
    22501 acttagatga agatgcagag gcaatttcac atgatgactc ttctgcaata gaaatagaaa
    22561 ctgtggattt atctttacca aaagggataa gtatagatga ccctgtaaga atgtacttaa
    22621 aagaaatagg aaaaattcct ctacttaaac cacatgaaga agtagaattt gctagaagga
    22681 tgcacgaagg tgatgagata gcaaaacaaa ggttagttga agcaaactta agactagttg
    22741 taagtatagc aaaaagatat gtaggaagag gtatgctttt cttggattta atacaagagg
    22801 gaaatttagg tcttataaaa gcagtcgaaa aatttgacta tacaaaagga tataagttta
    22861 gtacttatgc aacatggtgg ataagacaag ctataacacg tgctattgca gaccaagcta
    22921 gaactataag aataccagtt catatggtag agactataaa taagctaata agagtatcaa
    22981 gacaactact tcaagaactt ggaagagatc caaaaccaga agaaattgca aaagaaatgg
    23041 aaatgacaga agataaagta agagaaataa tgaaaatagc tcaagaccct gtgtctttag
    23101 aaacaccaat aggagaagaa gaagatagcc atttaggtga ctttattcca gatgatgatg
    23161 ctccagcccc agcagaggca gcagcatatt ctttattaaa agaacaaata gaagatgtac
    23221 ttggttcatt aaatgataga gaacaaaaag tattaaagct tagatttggt cttgaggatg
    23281 gtagagccag aactcttgag gaagttggaa aagagtttga tgtaactaga gagagaataa
    23341 gacagataga agcaaaagca ctaagaaaac taagacatcc aagtagatca aaaaaactta
    23401 gagattattt agactaaaaa gatacatcat tgatgttttt gtgataaatg ccatgagata
    23461 agtgatatct catggctatt ttgtagtaaa gatttaattt tatttttgta gttatttcag
    23521 tctaatatct ataacttgga ttaaatccta taaataaagg gaattgaaag gagaattata
    23581 tttgaaatta acagatagat tattgaaaat agcatcatta gtgtcagatg gtaaaaaaat
    23641 agctgatata gggacggacc acggatacat accagtatat ttgttaaaag agggaaaagt
    23701 accatttgca gtgctagcgg atgttaataa aggacctctt gacaatgcac ataaagaagt
    23761 catacagaac aatcttttag ataaagttga tttacgattg ggttctggta tagagatact
    23821 tgaaataggg gaagtagaag aagtgataat tgctggtatg ggtggaatct tgataagtga
    23881 gcttctcgag gctaaaaaag aagtagcaca taatgtagaa aaattaatat tacagccaat
    23941 gcaagcacaa gaagaactta gatattacct tttaaacaac ggatatgaaa ttttagaaga
    24001 agttttagtg agagaagatt ttagaatata tgagataatt gttgccaaat atacaggtaa
    24061 aaatactata atagaagatg agatatatta tgaggttgga ataaagcttt tagaaaacaa
    24121 agattctctt tttaatgatt ttatagaaaa aaagataaag acatatagtt ctatagttaa
    24181 taaattagaa gggaaaaatg gggaagctat agataagaag agaaaggaaa gcgaagttgc
    24241 aataaaaaaa cttgaaaatt taataaaata aataggaggt atatatgcta ttaaagagtc
    24301 taactagaaa aattgaaaaa aagtatcctc taaacttagc agaggattgg gataatgtag
    24361 gtcttatagt tggagatttt gatatggatg taaaaaaggt attggtatct ttagaagcta
    24421 atgaagatgt tattgatgaa gctatatcca aaaatataga tttaattgtg acacatcatc
    24481 cttttatatt tgggaaaatt aataaaatta atagtggaga tttaaaaggc agacttatcc
    24541 aaaaacttat taaaaatgat atatcacttt attctatgca tacgaatttt gatatagcat
    24601 ttgatggtct aaatgactat tttatggaaa ttatggaatt tggtaattca aaggttttag
    24661 atataactaa aagcgaaaat ttgtataaat tagcagtata cgttccacat aactattcag
    24721 atgaacttag aaaggtttta agtaattcag gagcaggtca tatagggaat tatagtgatt
    24781 gtacgttttc aatagaaggt gaaggacaat ttaagccatt agaaggctct aatccgtttc
    24841 ttggaagtgt aaatgatata gaaactgtaa atgaagttaa aattgaaact gtagtaccac
    24901 agaagctttt aggtggggta ataagttcta tgttagatgc acatccttat gaagaagttg
    24961 catatgattt gtacaagtta gaaaataaag gtgagatatt tggactaggt agaataagta
    25021 aacttgataa aagtatgaca ttagaaagtc tttcaaggaa aataaaagag aaattaaata
    25081 tgaaacacat aagagtagtt ggaaacctta gtacagacat aacgaaagta gccgttgtaa
    25141 caggagctgg ttcagaattt gtaaaaaaag ctaagagaca aggtgcagaa gtactaatta
    25201 cgggtgatgt aaagtatcat gaggcacaag atgcacttga tattggaatg tgtatagtgg
    25261 attgtggtca ttttgataca gaagatatat tcaaaaatgt tatgaagaga tttttagatg
    25321 aatttagtga aattgaagta ataaaaagta atgtatattt gaatccattt agtactattt
    25381 agcagtgttt gataataaaa atactatata aaaaataaat ttgagtttaa ttagggggat
    25441 aatgatgaaa gtagcagtaa tttttcatag tgtttgtggg agtacatatt tattagctag
    25501 agaatataaa gaagcgcttg aagaaatgaa tatcgaggta gatatattta gagtaagtga
    25561 cgaagttgca aaaacacttc ctcaatatta tttgataaat tccaaagaat acaaagacga
    25621 atttgaaagt ataaatgtaa ttaaatctgg aaaagaaata ttagattatg atgctatatt
    25681 tatgggttca ccaacatatt atggaaatgt atctggacca atgaagatgt ttatggatag
    25741 tttttctgat atttgggtag gtactccttt gagtggtaaa atatttggtt gttttgctac
    25801 agcaggttca caacatggag gaggagaatt agctttgcaa gctatgaata tatttgccca
    25861 acatatggga atgactcttt tgtcagttcc atgttcagta agaggaggtt atccagcgta
    25921 tggaatactt catatagcag gagataattc tgatataaga ccaaatgatg atgccaagat
    25981 aggtataaga gattacctaa aaagacttaa catataagaa tatcatataa aaatacctaa
    26041 aagcgactgt atatactttt aggtattttt acttaattat aaacgtgaag ctttaccaga
    26101 aatatggtca atttctattt taacaacagt tgttaagttc atatccttct ctatgtactt
    26161 catgccttct tcaaagaatc ctttagaata tttttttatt atttctacaa gagcattttt
    26221 cttttcttca ttttctacag tgcaagcttt tccaaaaact atagcactag aataagtagt
    26281 actaaattta tctggaataa cactttcatt agcaactact aaaaaagaaa ctttgttgtt
    26341 tttcgatata ttatctaact tatgcccatt tcttgcacaa tgaaagtaaa tagaatcatt
    26401 aaagtataca taatttacag caactccata aggataacca ttttcagata tagtggaaaa
    26461 agtaccaaat tcaccatttt ttaatacttc aacagtatct tcttttgtca tttctctttt
    26521 tttcaatctc atttctttaa acataatatc atcctttcta attttgatgc ttaaattaaa
    26581 ttttagaaca tttataaaga ttatgctatg ttttttacaa attttaagaa aaaaatatag
    26641 tttaagataa aaggtagtga aagagaagct atttggaggt ttatttatga tattattgtt
    26701 agagtagtat aaacaatact aataaattta atagctggtt tcttgttatt taagatagta
    26761 agcatgtcta taagaagggg aagttatcga gggtagaagt tgttatttat aactatatta
    26821 taaagaaaat attattatat aaaataataa atagtaaaga ggtatcaagt tgaatataat
    26881 acttaatacc tcttcaaaat taagttataa aagtgttgtg ggaattgtcc tatacatggt
    26941 aaggagataa taaagaatgt atctttaaag tctcaactaa acagcaaaat ttatccaaca
    27001 aacatacaat aaatgcttct ttgtatctag gtggcttaac agtaagtggc cacatgtgtt
    27061 ttaaaattat gtccgtttct ttttcattta tttgaaaaaa taaagttgca ttttttaatg
    27121 cttctctagg gtgagtaaat ccatgtaatc cttttctatc acctttgtaa tgccaatcat
    27181 aaagaaaaaa gtcgtgtagt aaagctcctc taataacact ttgaatatca acacttaagt
    27241 gcaatttttt acataataga taactataat atgctactga caaactatgt tcaagacatg
    27301 aaacattgcc atgatgagga aatgttctca taagttgaac tttttcagaa gaaagtatct
    27361 cagaagcaca ttcattaaaa tatttgattt cagcttttga caacattatg aaaatctcca
    27421 ttcttagtaa tatataaata ctatacttca acgataatat gaaatatttc ttatcctaca
    27481 aaatataata cccaataata caagtaagat accttttatg gtattttaaa gtaagagaga
    27541 ttttattagg ctaaacaatg aaaaaattaa aagtaaagct atagcaatat atagtatttt
    27601 tccaagagga ttgccaaaat ttatagtcca tccaatacca aaccttttat taaccattaa
    27661 tgatgggtca tttggattat tatacatgat gcctgctatc caatacttct catcttcttc
    27721 tggagaataa gatgagttga attttaaatt tggggaatta atatatgttg ctattaaata
    27781 aattataact aaaagcgttg taatattcat agcagttgat agttttgttt ttattgataa
    27841 aagagtagta aaaaactgtg ttgtcattat aatcatcaat attaaaaaca aataaccaat
    27901 tttatttaaa tatttaatgt tttcaactct actttcttca attctatttg tatctatctt
    27961 aatccttgac tttatggatc caatggaagt tatatataat aaaaccatta aacaaaagtc
    28021 agtaccgatt aatttaaata cattaagaaa tgatttatct ataaaaacat caggagaccc
    28081 atttatgttc caatgagtgg caattgagtc tggcaattga ttataattaa atgctataaa
    28141 aatactcatt cccaaagtaa atagtatcgg tattaaatag attattttaa atttttttat
    28201 tattttattt ttcttattta taaaatccat atctactatt aattttgaat ctatatctat
    28261 atgacctaat ttagaataaa tttctgattt aagcttctta gcttttttat gtgtatgaat
    28321 atatagtata ctttcatata ataaaaaacc tataatacca ataaaatagg aaagttccaa
    28381 tttattaaat gtaaagacca gaataaaaac taatataaag tctataataa aacctaaaga
    28441 taatagtttt ttaaattctt tatctaactt tataaagtaa ttataatttt tatgctcttg
    28501 gtctatagaa actccataga tgtgtttttt acctacaaaa tagggcataa aataaaatgt
    28561 agcatacatc aaaattagaa ctggaaatat tgtaaataga cattcaatct tactcataat
    28621 atttcacctc atacttgtca aataaacttg aacttagtga caaaaattct tctttactaa
    28681 tacctgataa ataagatttt gccaccaata attccaagtc aagtttattt ttttgacgag
    28741 ttgtattatc tattttcatt ggtagttgag ctacaatagc accttttctt ctatcaatat
    28801 ttaagaatcc ctcttctttt aattcattgt aggatttgtt cactgtatgt aaatttacac
    28861 caatattttc agccatactt cttacagatg gaagtgattc atttattttc aattctcctg
    28921 aagctatagc cttagttatt tcttctttaa tttgtacata aatagattta tcactattaa
    28981 aatctaaatt taaaaccata aaaaacctcc attatgcttt ataaatgaaa acgattgtta
    29041 tatacatagt ataacataaa aaataataac aaacacaaaa tataagttta tattttgtaa
    29101 aaattgtaat ttaaaaaata acataatttt tattaaaata atacagatac tatttataga
    29161 tagaaataaa aattagaaag gagaaaaaat atgttaacat atttaatgaa aagacaaatg
    29221 cataaaaaag atgatggaat gagtaaacca atgatgatta caggagctgt aattacaggt
    29281 gtaggagcat atgctgtata taaaatggta aaaagccata aatctaattc tcaaatggtc
    29341 aatacaaatt attatggaaa tagcgattat gatgattata aatatgacga atttgattat
    29401 gactgtgatt gtagagacac aaaacaagat tatgaatatg aagaattaaa aaaaaaagta
    29461 aaagaattta attcaagaag aataaattgt gaaaattgtc cacatgtttc tcaagaagaa
    29521 atgatgcaat atgtaaatag tgttaaagat gtaaaggaag agattgattt acatgaagat
    29581 gctaaaaaag ataatattta caaagaagat gaatacaaaa aatatgaaga agaataagta
    29641 atattttgta taactgaaca aatagtaatg tcaaattatt taatatctag ttttaatatg
    29701 taagttgtaa cttaacttga aagaatcagt atcattcttt agatagttaa gtaacaactt
    29761 acattttatt tttataaatt ttaatagttc tttgtgacta ttttgtaatt ttagaaatat
    29821 tttagtatcc agggtaattg tgtataataa aacttgtata gatagatagt atgaaattaa
    29881 gcagatagtt taaaattaaa atgaaaagaa aggaaatagt tatgttaaag ttgttgatag
    29941 ttgaagatga tagtactata tcttttggaa taaagtatgc tttagaacaa gaaggattta
    30001 gtatagatat atcaaaggat ttatctagtg gaaaagaaat gatttcttct aatgaatata
    30061 gcatgatact gttggatgtt acattgccag atggaactgg ttatgagctt tgtcaatata
    30121 taagaggatt ctctcaggtt cctataatat tcttgactgc ttgtgatgaa gaagtaaata
    30181 ttgtaatggg tctcgatata ggtggagatg attatataac aaaacctttt agaattagag
    30241 aattaatatc cagaataaaa gctgttttaa gaagaaaagg taatacttca gaagaaaata
    30301 agaaaatact taaatttgga gatttaagta tatatacatt agaagctaga gtatataaaa
    30361 atgataaaga aatatttctg acatcagttg aatataaact tcttttaatt cttatacaga
    30421 ataaaaatac tgttttaagt agaactcaaa tattggaaaa actttgggat gtaacttatg
    30481 attttgtaaa cgacaatact ctaactgttt atataaaaag gcttagagaa aaaataggtg
    30541 atgatttatg tgaaccaatc tacatagaaa ctgtaagggg gattggttat aaatggatag
    30601 gaagtgaaaa tagtgtttct atataatcca gaagtgaaga agtttttaag taagtatgtt
    30661 actttgatgt ttattgttat cataatatct attggattta gcataatcaa cgtgtcctta
    30721 actaaagaga tggttgtaag aaataatcag gctataatag gaactttatc aagtaagtat
    30781 ccaaacttgg aaagtcagat agtagacata ataactcaag ggaagtctat ggagaacata
    30841 gattatggtc agaaaatatt aattaagtat aattatgata aatctattag gataaactct
    30901 gagcctatta tttctaaatt agttttagag actatcaaaa taaatataat attagtatgt
    30961 ataatattta ttttgatatt tgtgttggtt gttagatatt ttaagtcaat ttacaatgat
    31021 ttatcagata tgactaagta tgtttactat agttcagagg gtaagccatt tgatatgaaa
    31081 aacaagaatc aagaagggca gataggtctt ctaaaaactg aactcttaaa gatgacaaca
    31141 attcttaatg aaaaggttga acttttaaaa agagaaaaga tatttttaaa caatacaatt
    31201 tccgatatat cacatcaatt aaaaactcct atgacttctt taataatgtt gaatgattta
    31261 ttatataatg atgtaccata cgaagtaaaa atcgattttt taaataagat aaaaaatcaa
    31321 ttaaatagaa tggattggtt gattaaaagc atgcttaaat tatcaaaggt agaagcaaaa
    31381 gtgataaatt ttaaaaaaga taaggtaaaa tttagtgaac tcatacatag agcaatgcta
    31441 tctatgaaaa tacctatgga gattaaaaat caaaaactga ctatagaggg aaatgataat
    31501 gtatcttata ttggtgatat tgattggtcc gtggaagcat tagtgaatat aatcaaaaat
    31561 tgtgtagaac atactcctga atttggaaat ataattataa cctataaaga aaatccatta
    31621 ttttctgaac taataataaa agatgagggt gaaggtatag ataaaaaaga tataccacat
    31681 gtatttaaac gattctatag aggaagaagt agttcaaaag aagatagtgt aggaataggt
    31741 cttgcaatgt caaaatctat aatagaaagc caaaatggcg atatatatgt aaacagcgaa
    31801 aaaggtcagg gtacagaatt tcatataata tttcataaaa tgtatgatag tgactaatct
    31861 gtaatattta attcacttta tagtaatagc caaaacctaa tatatgaagt atagaatata
    31921 aatattggag gtagttatgg aaattttaag agtagaaaat ctaactaaaa gttatggtaa
    31981 aaatgaaaca aaagttgatg ctataaaaaa tgtaagttta tcagttgaaa aaggaacgtt
    32041 tatagcaata acaggtccaa gtggaagtgg taaaagtacc ttattacatt tattaggagg
    32101 agttgacaga ccaactagtg gtaaggttta tataaatgat gttgatatat ataatttaaa
    32161 aactaaggat ttggcgatat ttagaagaag aaatataggt cttatatatc aattttacaa
    32221 cttaattcca gtcttaaatg tgaaggaaaa catattgctt ccagcagagc ttgacaatag
    32281 agatattgat agagaatatt ttgatgattt aatgaaaaca ttaggtctaa ttgatagaga
    32341 aaagcacctt ccaaaccaat tatcaggagg tcaacaacag agaacctcta taggacgtgc
    32401 attaattaat agaccttcta taatattagc agatgagcca acaggtaatt tagatagtaa
    32461 aaattcaaag gaaatattag aattgttaaa attgtcagta aaaaaataca accagacact
    32521 aataatgata actcatgaca aaaatatggc acttcaagct gatagaatta taagcataga
    32581 agatggaatc ataaaaagtg atgaggtgat gtagatgaat ttatatacat tactaaccat
    32641 tagatactta aaacaaaata aaagaagaac cattgtaacc ataatcggta taatactttc
    32701 aacagcttta atttgtggta taggaaatat atttgaaagt tttatggatt atcaaatgag
    32761 agaaactata aagaatgatg gaagtttcca tgttacattt tatgatgtaa atagaaaaaa
    32821 tgtggaatat gtaacgaaat cagctgaaat agaaaaacat gcatttacca aacaacttgg
    32881 atattctaaa ttagaaaata gtgaaaatgc tatattaagt ataaagcaat atgataaaaa
    32941 tgcaataaat ggatataaag tttctataaa agaaggtaga tttccagcta aggaaggaga
    33001 aattgttcta agtgaaagta ttattaatct tatagatgat aagttaaaaa taggagataa
    33061 gataacttta aaagtagggg atatgtttga ctcaagcaag aaaaagattg atagtatgac
    33121 atttcatgaa ggtgattata tagcaaatga aaaagataga acttttaaag ttgttggtat
    33181 aattgaaaaa cctgggtttg aacgttataa tggaattgca acagctatag cctactttaa
    33241 tcctatgaat aattacaatg atacaattaa tgtatcagta gcagtaagaa atcctaaaga
    33301 tgtgtataag ataagtaata aaataagtaa aaatatatat tcaaataaag ataaagaagc
    33361 agtttctgat atgataaaat acaatgaaca tttattgagg ttacaaggtg ctagtaagta
    33421 ttcaaatata aataactcta taaagtctat aattatagca gtaactattt tagtaatcat
    33481 atgtacaatt gctacagtgt acaattcctt tagtatttct ataaatgaac gaaaaaaaca
    33541 gtttgggata ttaaattcta taggtgctac atctagtcaa attaaaagat tagtttttat
    33601 agaaggtatt ataattagtt taattggtat accaatagga ctaatatctg gaacagtagc
    33661 tatagaccta ttgtttaaaa ttataaataa gtattttact gaatcggttg ttactaagat
    33721 gagtttgcag atagtgtata atccaataat aactattgtt agtataataa tagttttgct
    33781 tacaatcttt atatcaattc tactacctgc aatatcggct tctaatattt ctcaccttaa
    33841 tgtgattaaa aatactggag agtataaagt gggcaaaatc aaaagctcaa gacttattaa
    33901 aatgattttt aaaactgaag gagtacttgc atataaaaat attaggagaa atagaaaaaa
    33961 atttataata actctttttt ctttaatggt aagtataata atatttatat cttttagtgg
    34021 ctttacatta cttttactaa gaggtgaaga aattagaaat tctcaaagaa aatatgattt
    34081 gtatttaact gcaaagaaca cagctaggtc tgtagaggat actataagtg aactagaaga
    34141 tattgatggg ataaaaaact ttgaattggc aacaggacaa tatgtgtcta taagagtaag
    34201 tgaaaataaa ataaataaat ccaaggaaga tttaatcagg aaatattatc aaaaatataa
    34261 gattggagat agttatgaat atgatttcag taataatgaa ttaatttttc caggagattt
    34321 tgcagtaaaa aacaaaataa ataacttagt acagggctct tttaataaag agagagcaat
    34381 tgaagaaaat ggtgttatat tagttagaaa aagtgcattt gaagaaaatg ggaagaaagg
    34441 tgtagtagaa cttaccaact ataaagtagg agatacagta aattgtgaat atcttgatga
    34501 aaatgcctta agtaaaaaag taaaggtcaa gattcttgct ataactgacg aagaacgtct
    34561 aggtcttggt tatcaaaata tggggttaca atttataact tatgatgaag ttgctaaaaa
    34621 tttaaattta aaattaagta aaagccttat atttattgat tcaggaggaa gcattaagac
    34681 taagaaggaa atagaagctt tggcaaataa aaataatttt aacttttatg atgaaagtgc
    34741 aagcaatgaa agtgaaaaac aagatttaaa ggttattaaa atatttgtat atggttttat
    34801 agtagtgata tctttagtga gtgttacaaa tattctaaat acagtaagta caagtataaa
    34861 tctaagaaaa agagaacttg cagtaataca atctataggg gttactccta aaggatttag
    34921 gaaaatgata tatttagaaa gttttatata tggtatactg tcattgttgt ttggaatacc
    34981 aattagtatt ggtataattc taattatgaa taaacttatt tcaggtgtaa ttgaattttc
    35041 tccgattata ccgtggacag ccatagttat ctgtatagta agtgttttta taataacttt
    35101 tatagcaggg tatataccaa tgagtaaatt aaataaagaa aatataatag ataata
//
LOCUS       DAMKNB010000036        34761 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.038, whole genome shotgun sequence.
ACCESSION   DAMKNB010000036 DAMKNB010000000
VERSION     DAMKNB010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 34761)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34761)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34761
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.038"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            complement(441..2828)
                     /gene="cadA"
                     /locus_tag="PC494_001966"
     CDS             complement(441..2828)
                     /gene="cadA"
                     /locus_tag="PC494_001966"
                     /EC_number="7.2.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cadmium-translocating P-type ATPase"
                     /protein_id="HDF3912467.1"
                     /translation="MEANNSIKKEFILGGLNCAHCAEEINNKVSKLQEVKSSNLNFIN
                     KKLTVNIKESFNEDTTIEKIIDIIDSTEPGLDIQISSKENAASKTSIKKELILGGLNC
                     AHCAEEINNKVSKLKEVESSNLNFVNKKLTVNISNNFEEDDVINKIKEIINSTEPGLD
                     IQVGSTDKVKGRTTEKSGAVNDTNKKELIPLIIGALVYIFGIYQTATGYESQFSNIVF
                     IVAYVIVGGDVLLRAIRNISKGRVFDENFLMALATVGALTIGELSEAVGVMLFYKVGE
                     YLQGVAVGKSRKSITSLMQIRPDYANLKVNSEVKVVSPEEVNVGDIIVVKPGEKVPLD
                     GVVVDGVSMLDTSALTGESVLREVEKGDEILSGVINKNALLSIEVTKSFGESTVSKIL
                     DLVENSSIKKSKTENFISKFSRYYTPIVVIAALLIAFVPPLVISGEVFSDWLYRGLIF
                     LVVSCPCALVLSIPLSFFSGIGFASKNGILIKGSNYLEALRSVDIVVFDKTGTLTKGV
                     FNVTKLNPEGISEEELLEYAAIAEVNSNHPIAKSILSYYNKKIDLDTIDSYEEIAAYG
                     IRVKHNGNFILAGNEKLMKKENISYSSAKEVGTVVYIAVDKVYRGYIVISDEVKEDSK
                     NAIRSLKEIGVKEVVMLTGDNEKVAKNIAQELELDTVYSNLLPNEKVDRLEDLYEGRT
                     EKEKIAFVGDGINDAPVLARADVGIAMGGLGSDAAIEAADVVLMTDEPSKISKAIEIA
                     NKTNKIVWQNIIFALGVKIIVMILGAGGVATMWEAIFADVGVALIAVVNAMRAMR"
     gene            complement(2851..3216)
                     /locus_tag="PC494_001967"
     CDS             complement(2851..3216)
                     /locus_tag="PC494_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF3912468.1"
                     /translation="MREEINDCNCNIVHEEIVTEAKSTMPDEEMLYDLAELFKVFGDT
                     TRVKILYALFANEMCVCDIASLLNMTHSAISHQLRVLKQARLVKFRREGKTVYYSLDD
                     SHISQIFDCGLNHIRETYK"
     gene            3415..4263
                     /locus_tag="PC494_001968"
     CDS             3415..4263
                     /locus_tag="PC494_001968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3912469.1"
                     /translation="MSNKKKKDLDTSYMPYLDPANYADYITNEEIPQDELRNDPQISN
                     GYTKIPNNQNINNLYPNNVNHYPKSSNSPNNLPNTNNTSGNMNYNTSATNNMPNNMNN
                     NTGMPNNMSNNMNSNMGMPNNMPNNMNSNMGMPNNMPNNMNSNMGMPNNVPNNMNSNM
                     GMPNNMSNNMNSNMGMPNNMSGNMNNNMYGNTGMPNNMNSNMGYNMNNTMGIPNFSCN
                     QNMPPNVLMMIPGVICHNTMQGMPVVMPSTMPPNIYPTPYGSSNMSVQGIPQATNIEE
                     FDEEEM"
     gene            complement(4700..5788)
                     /locus_tag="PC494_001969"
     CDS             complement(4700..5788)
                     /locus_tag="PC494_001969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3912470.1"
                     /translation="MNFNFAKATNSRLMGSLGLIINWIDDENNHFCQYFLLDAEGLGL
                     ADYVSLNNPTQEEAYMEEERLMGGFGSDRVELTKDESLFLVSYFGNKNLYYDKLLPGD
                     KCEYIDIIKNYKTDLTIEKLYNKICKRVDEEVEFINYMTMRFIAWDRESLKYFSGSDE
                     IANMHITNINGTLLKNVVSDKGQGRYISEALYEDNDGYYICKIAFCISKCYETGFRIN
                     SLLVTDKEPMYDFEVFDEISKSEFVSVYSVNSPEEFAGVFYRENPFLLKSNMNEGIFF
                     TRFNFNNDHVKENVYIINNDMKAIYYLMGNKFFIGTYNENDCNYINEISQSNYSDYIK
                     FEEKFFFEQNALYDFAESGSLDFDDFLE"
     gene            5913..6641
                     /locus_tag="PC494_001970"
     CDS             5913..6641
                     /locus_tag="PC494_001970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IB family hydrolase"
                     /protein_id="HDF3912471.1"
                     /translation="MKNIAAFFDIDGTLYRDSLMVEHFKKLIKYDIIDQKNWYKHARD
                     TFMDWDKRQGNYDDYLLEICDLYVDSLKGLDKTCINFTSDQVIKLKADRVYKYTRSRI
                     EWHLNQGHIVIFISGSPGFLVEKMAKKYNVTDFLGSDYVFENNIFTGTVIPMWDSISK
                     NNAINDFVVKYDLDLSNSYAYGDTNGDINMLKRVGNPIAINPTKELLSQISLDEEISK
                     NVEIIVERKDIIYSLSTDVNIVDI"
     gene            complement(6843..7334)
                     /locus_tag="PC494_001971"
     CDS             complement(6843..7334)
                     /locus_tag="PC494_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3912472.1"
                     /translation="MSIKVAYGGVLLALNVILLTLTNIIPVNTLFIMGLASLLVSIVI
                     MEWGFKSGIAFYIGSIVLGFIVMASKSQWIVYSLTFGIYGIVKYLIEKDRSIYIEYFM
                     KLVFANIMILILYFLLRTIVYIPINIFIIGSFEIAFIVYDYVYSSFIGYYNNRLRKML
                     FKK"
     gene            complement(7345..7788)
                     /locus_tag="PC494_001972"
     CDS             complement(7345..7788)
                     /locus_tag="PC494_001972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3912473.1"
                     /translation="MYSNTYNNENFMRARSFIENSEFKKAYDFLKTLTDKCAEWYYLT
                     GFSAMNIGYYEEGEDFLKRAKFMEPENSEYSDALRSYTQYRNDYSNRADNYNRRRRND
                     LDGCCCCCCDDCCCCLGDDCCENCAKLWCLDSCCECFGGDLITCC"
     gene            complement(7778..8617)
                     /locus_tag="PC494_001973"
     CDS             complement(7778..8617)
                     /locus_tag="PC494_001973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3912474.1"
                     /translation="MFGYVKINKMDLTFREYDYYKAYYCGLCKYLKRNHGEISRFSLN
                     YDITFLIVLLTAVYNPESISTEEVCIVNPFKKKKVITNDITEYAASMNILLTYYKLED
                     NLMDDKRIKDKLAYYIYKNKLKLAYEKYPEKAEYIKQQLNELNKLEKDKNINIDEVSS
                     IFGNIMGEVFVYKKDENERNLRMIGFNIGKYIYLLDAYEDLDEDFKKGRYNPFIEYID
                     KNDELKEKVKKIIVTSLGFLARGIDNLNLNKNVGIIENIIYSGVYLRYINILESRGGK
                     NVQ"
     gene            complement(8836..10221)
                     /locus_tag="PC494_001974"
     CDS             complement(8836..10221)
                     /locus_tag="PC494_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HDF3912475.1"
                     /translation="MDNLNKKFLMEYIDEIQGELRDISDKIWKNPELQYKEYYASNLQ
                     KECLKKHGFSIEGLEGMDTAFVASYGEGRPVIAVLGEYDALDGLSQKVSTTKEPIVDG
                     GAGHGCGHNLLGTGSIGAVIAVKELIKLKKLKGTIKYYGCPAEEDLSGKVLMIKKGFF
                     DGIDCAFSWHPFDINTPIRIPTLANYSVKFRYNGISAHAAQAPYNGRSALDAVELMNI
                     GCNYLREHIFDNCRVHYVTTNGGKMPNIVPDFAEVWYYIRGVKMEHVRDVFGRIVDIA
                     KGAALMTGTIMEYDIISGVYDYIPNTILTDILSQNMKLVGVQNYNEDDYYFADKLAET
                     VSIDKRSSVSSVLSGNKDITKMNLHDEVTDDTFTHNNCISLSLDIGDVSYIIPTAQCS
                     CSVWPIGISAHTWQSCASAGSDMGFKAMLLASKSISCSINDVMLDELVINKAKKELKD
                     TVGSFKYIPII"
     gene            complement(10394..11137)
                     /locus_tag="PC494_001975"
     CDS             complement(10394..11137)
                     /locus_tag="PC494_001975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytoplasmic protein"
                     /protein_id="HDF3912476.1"
                     /translation="MKKVLIVGESWVKNITHIKGFDTFVTTHYEEAVKWLKEAIESGG
                     YETVHMPAHVAADSFPYKLEELNEYDCIILSDIGSNTFLLSNSTFIDCNSNPDRLELI
                     KEYVNNGGALIMVGGYMSFTGIDAKARFGETAIKDVLPITMIDKDDRVEKPAGIIPEV
                     IDSEHPVLKGIPTEWPKFLGYNKTVARDNCPVLATIGGDPFVAVGEFGKGKSAIFSSD
                     CAPHWGPKEFTDWKYYNKLWVNMLDWLTC"
     gene            complement(11157..12419)
                     /locus_tag="PC494_001976"
     CDS             complement(11157..12419)
                     /locus_tag="PC494_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HDF3912477.1"
                     /translation="MKKILLDTLNSKKQEYIDYLKELVSIKTEDVGHGILGGFEKEGQ
                     EYIEKLANYIGFSVDRQEMSEELIKKAKNIYKEGNLGHNYQDRYNLICKYSDDLPGKT
                     IVFNGHVDTMPPGDISKWKYNPYRATEDNGKLYGLGTADMKSGLIASILAVKLIKDSG
                     LNVPGNVKIMSVVDEEGGGNGTINAVMNGIDGDCCIICEPSEQNLIVAHMGFVFFEVE
                     VKGVSLHCGSKWEGVNAIEKAMLLLQDIKELEHNWLMIYKHPLLPSPTINLGVINGGT
                     AGSTVPDKCVFNLCVHFLPNIMSYEQVVNDVTNVIMTRANGDLWLKDNKPNINIYQSG
                     LGFEMDKDSDFVVNAHKILEETLGKKLEIKGSTAGNDARVMKNLAEIPTLILGPGSIE
                     QCHSIDEYVEIKEYLDSILMYASLILNL"
     gene            complement(12603..13601)
                     /locus_tag="PC494_001977"
     CDS             complement(12603..13601)
                     /locus_tag="PC494_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose ABC transporter permease"
                     /protein_id="HDF3912478.1"
                     /translation="MSSITKHKEEKSSPLLTKLTSVFRDQGSAAVGLVIIFIIMSVAS
                     SNFLTLDNLINVGRQISINAILAVGMTFVIITGGIDLSVGAVIALVGTFWATTVVNYN
                     APIWVGMILALAIGTILGVIKGAIISTQKLPPFIVTLAMLTIISGASFVFTGGRPISV
                     NTDAFKMLGRGYIGPIPIPVIIMIIVVIAGHFLLKRTNFGRHVHAVGGNEEAARLCGV
                     KVNKVIVKVYALAGLLTALAGIILSSRLASGSPTVGDGAELDAIAAVVLGGTNMMGGS
                     GSIVGTCIGVGIIGILGNGLNLLSVSSYNQMIIKGLVMLFAIWINNIKLKKSAKSK"
     gene            complement(13585..15096)
                     /locus_tag="PC494_001978"
     CDS             complement(13585..15096)
                     /locus_tag="PC494_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter ATP-binding protein"
                     /protein_id="HDF3912479.1"
                     /translation="MSNIILKLSNIAKEFPGVRALDNVNFELFHGEVHALLGENGAGK
                     STMIKILTGAHSKTSGKFIFEGKEIENISPDISKKIGINAIYQELTVFDELTVAQNIF
                     MGKEINGKVLTNDKKMNEEAKKIFDNMGIDINPNSLVKELSIAQKQMVEIARVLSSET
                     KVLIMDEPTSSISKKETEILFRLINDLKESGVSIIYISHRMEELFEICDRITIMRDGK
                     TISTLNTKDVSSEEELVNLMIDRKLDQFFPKRKVEIKEEIMRVENLTKNNVFNDISFN
                     IRKGEILGIGGLVGSKRSEIVEAIFGLRTYDSGKIYLNNEEVKFKTPSDAIENGLGLI
                     TEDRKGTGLFLQMSVKENTTMAGLKKISKFKSIIDRKKEKEILEKYIEALKIKTPHMN
                     QVIQSLSGGNQQKAIIARWLLLQPDILIMDEPTRGIDVNAKAEIYNLMGDLVESGVSI
                     IMISSEIPELISMSDRIMVMREGHISGFLEGEEMVENNVLKLAFGGKINEFNN"
     gene            complement(15150..16112)
                     /locus_tag="PC494_001979"
     CDS             complement(15150..16112)
                     /locus_tag="PC494_001979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HDF3912480.1"
                     /translation="MRVRKILSLGIAGILAIGMLTGCSMEGPSKSDNKGGSDKKDLTI
                     GVSTITLQHQFFIDIDEGIKEKAKELGVKVIVNDPDQDVAKQTSAIEDFIQQNVDGMI
                     VLGTDNSAIVPAVEGAFEKMPVVTVDAVLNTENITSYVGTVSYDAGKKLGEYTKKYID
                     EKLGGKSEIAIVTDLKSQIQMQRIDGFKDALKGSANVKILNSQPGYDREESLNTVENL
                     IQSNPDVDIIYATAENSVLGAKAALESAKNKDVKIVGFDLTEEASSGITDGTILAMIQ
                     QQPKEMGRLAVEAVVKAIKGEKVEKNIPVPALLYDKENIKDFKN"
     gene            complement(16160..17050)
                     /gene="rbsK"
                     /locus_tag="PC494_001980"
     CDS             complement(16160..17050)
                     /gene="rbsK"
                     /locus_tag="PC494_001980"
                     /EC_number="2.7.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribokinase"
                     /protein_id="HDF3912481.1"
                     /translation="MGNIVVIGSVNMDMVCSVDKRPEKGETVLGNSFFTSPGGKGANQ
                     AISASKLGANVKMISCIGEDGLGEELIRNFRTNKVDYSLVSRNNHKSSGVAVITLCEN
                     DNSIVVVPGTNELVDIELIKKNEEEIKNADIVLLQLEIPLKTINYVVNFCFENRIRVL
                     LNPAPAVKLNEDIIEKVTYLTPNEHEYKIVFDTNEGIEEVLKKYPNKLVITEGKNGAR
                     FYDGEEIKHVSCISVDVQDTTGAGDTFNGALAVAITEGKNLYTAVEYAVVVSGLSVTK
                     LGAQSGMPYKEDVEKYLNNK"
     gene            complement(17092..18105)
                     /locus_tag="PC494_001981"
     CDS             complement(17092..18105)
                     /locus_tag="PC494_001981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HDF3912482.1"
                     /translation="MSITIKEIGELAGVSKTTVSKVINNKDENISQATREKILKIMKE
                     KNYVPNKLAQSLVTKKTNTIGLLIPDIRNPFFTDVSRGVEDKANEEGYNIILCNTDED
                     AKKEYEGIRTLSERMIDGIIFAASSNTNWKEANYKDIKIPTVLIDKKISMNKETLKGI
                     VKINNFEGAYIATKHLLDIGNKKIIYLSGPLQNEIAVDRLEGYKKALIECNLSYNPAY
                     VFEGKYKIEWGQEFIKNLEKIDFDAIFCANDLIAIGVIRGLKERGLSIPNDISVVGFD
                     DIQTSSLISPSLTTVKQPSYDIGYKASEILINCLRGDKKESFDELIFKPELVIRDSTK
                     ESE"
     gene            complement(18334..19311)
                     /gene="bioB"
                     /locus_tag="PC494_001982"
     CDS             complement(18334..19311)
                     /gene="bioB"
                     /locus_tag="PC494_001982"
                     /EC_number="2.8.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin synthase BioB"
                     /protein_id="HDF3912483.1"
                     /translation="MEKYIIKLKNKVLREKEISYEEALNLISLDTNNKNDFDILLKSA
                     NEIREYFMGRKADLCTIMNAKSGKCSEDCKFCAQSSYYKTGVEEYSLLDYNEILNRAK
                     EMESKGVHRFSLVTSGKGMSGKEFNNILNIYEGLRENTNLKLCASLGIIDYEQAKMLK
                     SAGVTTYHHNVETCRDNFHNICTTHTYKDRIKTIKDAKKAGLDVCVGGIIGMNESEEQ
                     RLKMAFEIRELNVKSFPINILNPIKNTPMENYDVLEPMEILKTTAVFRFIIPNVYIRY
                     AGGRLSLKGYDKVGFNGGVNSAIVGDYLTTVGSGIENDKKMIIEQGFEF"
     gene            complement(19517..19780)
                     /locus_tag="PC494_001983"
     CDS             complement(19517..19780)
                     /locus_tag="PC494_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3912484.1"
                     /translation="MKIYYEKENSKKANVNNIPSVFAFNFLRNFLTSKEYEETRKEYF
                     INNLTKSQVNQAMKDLKWLFREYEGLEVITMESLDGVKTRIVL"
     gene            complement(19850..20923)
                     /locus_tag="PC494_001984"
     CDS             complement(19850..20923)
                     /locus_tag="PC494_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF362 domain-containing protein"
                     /protein_id="HDF3912485.1"
                     /translation="MEKSKVYFCDLYSNSQNKNVPNNVRRLFDEAGFKDLIEKNDQVA
                     IKLHFGEKGNTTYMSPVAVRQVVDKVKDCEGKPFLTDTNTLYTGSRTNSVDHLTTAIE
                     NGFAYAVVNAPVIIADGLYSRNYENVKIDKKHFESVKIGGEIYNSSAMIVMSHFKGHE
                     AAGFGGALKNLAMGCASAAGKQMQHSDVTPVVKEKKCVGCGKCVNSCPTKAISIVDKK
                     AVIDSDVCYGCGECPTVCPTRAVTIQWESDSDVFVEKMAEYAYGAVSNKKDKVGYITF
                     VMNVTPLCDCVPWSGRPIAHDIGILASTDPVAIEQACYDLICKEMGHDVFKHEHPHVN
                     GTRIIDYACEMGMGSKEYELIKL"
     gene            complement(21182..21940)
                     /locus_tag="PC494_001985"
     CDS             complement(21182..21940)
                     /locus_tag="PC494_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF3912486.1"
                     /translation="MREYIAFTKKEFKENLRNYKLFSLIILFLIFGISSPISAKFMPD
                     LIAHFAPTLKVTAAPTALDSWTQFFSNISGLGMSLTLIIFCNILSNEYSKGTLVIMLT
                     KGLSRSSIVLSKFSVTVIIMTIGFWLSFLFAYGYTMYFWPTANLNHIIFSAFNLWLIG
                     IMYISVLILGCVLFRPAFASVLLVLVATLLLSLISIPKQIAPYTPNFLMSKNIDLISG
                     KVAMPEFIIPIIITVLISIVCLLAAVILFNKKPV"
     gene            complement(21937..22854)
                     /locus_tag="PC494_001986"
     CDS             complement(21937..22854)
                     /locus_tag="PC494_001986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF3912487.1"
                     /translation="MNIVSINGLSKGFGNRKIIDNLNFTVPEGSVFGFVGKNGAGKTT
                     TMKMVLGLLKPDGGTIDVCGEKVTYGKTSSNRHVGYLPDVPEFYNYMRPLEYLSLCGE
                     ITGLSKKEIQIRSEELLSLVGLGNEKRRIGGFSRGMKQRLGIAQALLSRPKLLICDEP
                     TSALDPVGRKEILDIMLKIKDSTTVIFSTHILSDVERICDHVAILNKGSIALSGTLSE
                     IKSMHGKDRLLLEFASNDEIQKFKSSDGIKSLLKDSEETNMEIVLHGKDIKAIQKTVI
                     STLAEMNLCPVKMELIELSLENLFLEVVK"
     gene            complement(22854..23054)
                     /locus_tag="PC494_001987"
     CDS             complement(22854..23054)
                     /locus_tag="PC494_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLDc_N domain-containing protein"
                     /protein_id="HDF3912488.1"
                     /translation="MENLMEYLPLLVPVIILDLILIITALVHVLRHPNYKIGNKAIWI
                     IVVLFISLIGPILYFTIGRGEE"
     gene            complement(23059..24153)
                     /locus_tag="PC494_001988"
     CDS             complement(23059..24153)
                     /locus_tag="PC494_001988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF3912489.1"
                     /translation="MNELNIAKTLILKRKEKGITQDELANYIGVSKASVSKWETGQSY
                     PDITFLPQLATYFNITVDELICYEPQMMKEDINKLYNKLCKDFTVKPFDEVMDEIREI
                     IKKYYSCFPLIFRMGLLIVNHYDIVDEKKRELLISEALEIFIRIQETCNDIDICRQAK
                     SMEATCYILLNQPIQVIDLLQNSNFPMINESILLAQGQMMNGQMDEARETFQLGAYQN
                     LISLVQNLVGILQNADKLQMKEIERRILAISDIFELDTLSPAIMLSSYLTQAQINLIH
                     GDNEGAIKSLRKYVDLATRDIYPIIIHGDDFFNKLDRWISEIGTGITRDDTIVKAGIV
                     AAIKNNPMFSVLSENKEYKFLIEKLSLLEE"
     gene            complement(24663..24803)
                     /locus_tag="PC494_001989"
     CDS             complement(24663..24803)
                     /locus_tag="PC494_001989"
                     /inference="COORDINATES: protein motif:HMM:NF021468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2185 domain-containing protein"
                     /protein_id="HDF3912490.1"
                     /translation="MNGEGCILSNKITKECYKVGYMIREKSIDIYPDSGWGFMTWDEN
                     GE"
     gene            complement(25113..26420)
                     /locus_tag="PC494_001990"
     CDS             complement(25113..26420)
                     /locus_tag="PC494_001990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HDF3912491.1"
                     /translation="MDISRSVDNSLNRTIEFLKELIKIDSQQGEPISQCPFGIGPKKS
                     LDKTLDYCASLGFSVKNIDNYIGYAEIGEGEELIGIPMHLDIVPPGEGWSVDPFSGAV
                     IDNIIYGRGVIDNKGAVSMLIHVLKNIEDMYPTINKRIRLIFGTNEETGMKCIKYYLD
                     KGEEIPSMGFTPDAMYPVVNGEKGRVHIRIEKEIKIDKSKPYIIVSGGTKENVVPSHC
                     TAKIINGIISELTTKGVAVHASNPEKGENAISKMVIKIVEDNMDFQHREDIELVSKYL
                     CSDYYGDALGINQYDEVFKNTTLNLGILKVNEEKIVCELDIRYGKNIVLNNIIDRFKK
                     VFCNGWKIEVIAHKDLHYVDESNLVLKKLLEAYEEVTDENGYTIAMGGGTYASWFKDM
                     VAFGPKFLAYKTGGHGVDERVPINHIRKNMEIYTLALIKLLEL"
     gene            complement(26485..26964)
                     /locus_tag="PC494_001991"
     CDS             complement(26485..26964)
                     /locus_tag="PC494_001991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-2-amino-thiazoline-4-carboxylic acid
                     hydrolase"
                     /protein_id="HDF3912492.1"
                     /translation="MSEKMYTEKEYLEGIRGATGERAVWFYLLMKEAEKLGANPDDIC
                     KEAIYGFGKMRGQKYNVADTPGKMAEMLYNSKGQKVFEMELVENTDENGVLKFHHCPL
                     DAAWKEYGLTKEERKEICRLACYGDYGRVDCAQGVKLDFAQKCAHDDEVCELVFTKK"
     gene            complement(27011..27874)
                     /locus_tag="PC494_001992"
     CDS             complement(27011..27874)
                     /locus_tag="PC494_001992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HDF3912493.1"
                     /translation="MQEIKNKEVKNGQGPTEVNKTRVLTKKDVTKTYLRWWWTAELSN
                     SFERMQALAVCASFTPALEKLYKRKEDLVDALKRHLQFFNTQAIWGGLIHGTVLAMEE
                     EKATEGKIPGEVISGVKNGLMGPLAGIGDTLDFGTFQTIFLALGASFGAEGSVIGAFF
                     PIMFSILLFCEGYYLFHLGYSLGRDSIKKILSGGIVNKIIDGASILGMFMMGALSATT
                     VKLSTPLSFDIGGKAIVVQDTLNMIAPGLLPLGVVFFVYWGMKYKKWTITKLLVILVV
                     LALVGSFIGIF"
     gene            complement(27874..28629)
                     /locus_tag="PC494_001993"
     CDS             complement(27874..28629)
                     /locus_tag="PC494_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDF3912494.1"
                     /translation="MESVLMLAIVTGLWYWFAAGLAGYTLFSTLKSPLFIGFSLGLLW
                     GDVTTGMIVGASIEMVYLGMVAAGGNIPSDKCLAALIAIPVALQTGVNAEVAVSIAVP
                     LGVIGVLVNNLRRTGNAVLVHKADKYAEEGNTKGIWRCATLYSLIFGFVLRFPIVFVC
                     NFFGADLVQSLLDVIPQWLMNGLTVMGGILPALGFATTIFTIGKNKFLPMFIIGFFMV
                     QYFEISITAAAIFGVCIALLITFMKEDKRVGEV"
     gene            complement(28656..29144)
                     /locus_tag="PC494_001994"
     CDS             complement(28656..29144)
                     /locus_tag="PC494_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDF3912495.1"
                     /translation="MAKITLVRVDHRLIHGQVITKWVKIAQAQKIIIVDDFLGQDEFM
                     ADIYKMAAPSGVEVVILTAEDAGQAFQNNTLGDKNIFILFKNVDMANKAYKAGLKYEK
                     IQLGGIPNEAGKKMVFTAVSLGNEDVEQLNELNENGVEIVLQVIPEESSMTYENALKK
                     FK"
     gene            complement(29162..29563)
                     /locus_tag="PC494_001995"
     CDS             complement(29162..29563)
                     /locus_tag="PC494_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIC"
                     /protein_id="HDF3912496.1"
                     /translation="MNKYKVIILCHGTWGKVLVEETNKNFGLSNQYEVLSLSSEKDVS
                     VFMKEVEEVVDKEDVKIIISDLYGGSTSSVAIAVAIRRGIDAINGLSLQTILIVDEEL
                     SKEDKLHTLPERIVKKNNNLCVDLIKEFKKI"
     gene            complement(29566..30063)
                     /locus_tag="PC494_001996"
     CDS             complement(29566..30063)
                     /locus_tag="PC494_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDF3912497.1"
                     /translation="MSLVKYCRCDDRLIHGQVIYKWVKHLGVKKIVVVDDETTNDVIA
                     KGLIKMAAPKNIDLSILTVSESRRYFYNNQADDNVFVLIKNLDTANRMIEEGINIKKL
                     IVGRIPTGIGKKKISQNVYINKKEFLLIDEFIKKNINVSIQMVPDEEEVELNQNINRY
                     KGEFI"
     gene            complement(30087..30491)
                     /locus_tag="PC494_001997"
     CDS             complement(30087..30491)
                     /locus_tag="PC494_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDF3912498.1"
                     /translation="MIGIIVMTHGSFSEEIIKSCELIAGPAERTAAIKLNRNDNIEDL
                     NKNFVEKLNELDEGDGVLVLADLLGGSPSNVASLNLKKGGKFHALTGVNLPMLLEALI
                     NREGKSLEELAEACIEAGQTGINNINKVLSSM"
     gene            complement(30721..33288)
                     /locus_tag="PC494_001998"
     CDS             complement(30721..33288)
                     /locus_tag="PC494_001998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDF3912499.1"
                     /translation="MTQKKLSRKEKVLICLKRLTEEHLNFNNGIRFGFDAEYIATEVG
                     INRSNASKELNQLIKESIIIKIKGKPVQYLYKESIESILGKKLNKGIFDNINSINEYS
                     ENDSIKDEYILESIKKENNIFNLVGCDGSLRSQIEQAKAAVIYPPKGLSTLIIGPTGV
                     GKSIFAEYMYKYSLTIKEDSDNAPFIIFNCADYSDNQQLLLAQLFGYVKGAFTGADKD
                     KYGIVHEANNGVLFLDEVHRLSAEGQEMLFLLMDKGIYRRLGEANKVHECRVMIIAAT
                     TEDPETAMLETFLRRIPVTIKIPSLEERGFQERMKLICYFFKEESVRIGVKLKVSKEV
                     IKAFILYKCKGNIGQLKSDIQLICARAFLDYMTYKRECVYVRLSLLPNNIRESLYGNN
                     RKEEFVQNFSFIGKDDIIFLPEEKDFESENLLIENKKYDLDFYGMIKETWNKLQQEGI
                     KESQIRSVIDGDIQKYSYNLMNTFIYNSSNQTAYNNIVNDSIATTVKYILQKHDKWSK
                     REGLDKLIKAIALHIQNLIERIKIGNIVKHPNKDEIMKERAYEYNIAKEILSNMSLMY
                     GVEFPEDEAIFLATFLYLSYVGLNEESIAILVIMHGESTASSMVNVANTLLDCNHAVA
                     INMGLEDRVQDILVQAVEIANKIDKGKGILILTDMGSILTFAKVIRDATGKEVKAIDM
                     VSTPIVIEATRKALTPEMTLEKLYFNIIESIKKHYGDMEVTYAEKDNGGRYFDRLLID
                     NISKTLTFLNGEKAYFILKEVINRISEHYSLVIQDELLVKFIFHCSCMIERVIIKESL
                     VYKSYEERISRNKELYLVIKESFKLVEETFDIIISDMEYANILDIFESQYDTDKFKS"
     gene            33454..34197
                     /locus_tag="PC494_001999"
     CDS             33454..34197
                     /locus_tag="PC494_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase"
                     /protein_id="HDF3912500.1"
                     /translation="MNFLSDLHTHSIVSGHGYSTLLENINYCKENGIKILGTSEHGPK
                     MPGSPHKWYFHNIQNIPRIINNIIILRGCEANILDIKGNIDLEPFVIPRLDYLILSFH
                     EAVFSPNTLENNTKALINAINKHDNIEILGHLGNSNYPIDYELIIKLAIEKNILIEIN
                     NCSIKGVSRNGSSDNCKYIATLCKKYGAKIILTSDAHICFDIGNYEYSENILKEINFP
                     DELIMNYPKKLINHFHQKGKLLDVDYTNI"
BASE COUNT        11268 a         6359 c         3561 g        13573 t
ORIGIN      
        1 cttaaaaata attcgtcaat actttttaaa attatttttt aaaaatattt actttcttat
       61 attacataat ttattgaatg gcagtcatac tgttggttta gagtatttta acacacacat
      121 tttgttgtaa aaattacaac tattaatata atatatatac aatcataagt attataattt
      181 ttatgaatct aatttaaact taatataaac ttattaataa accttctatg tctaaatttt
      241 aaaattacaa tataaaagct ctacactaaa taaatacatt aaataaacat aatggataat
      301 gaatataaat ttatatatgc aaagcgctcc aataaaaagg taccaataaa gttaaaagaa
      361 acttattgat acctttcatt attacatact tcaatatata attataagtt ttttaaatag
      421 tatggattta catttatccc ttatctcata gctctcatag catttactac tgctataagt
      481 gccacaccta catcagcaaa tatagcttcc cacatagtag ctactcctcc agcacctagt
      541 atcataacta taatttttac tcctagagca aatattatgt tttgccacac tatcttatta
      601 gtcttgtttg ctatttcaat tgctttagat atcttgctag gctcatctgt cataagcact
      661 acatctgcag cttcaatagc agcatctgaa cctaagcctc ccatagctat accaacatca
      721 gcacgagcta atactggagc atcatttatt ccatcaccta caaacgctat tttctctttt
      781 tcagttcttc cttcatataa atcttctaat ctatctacct tttcattagg aagtaaattt
      841 gagtaaactg tatccaattc taattcttga gcaatatttt ttgctacttt ctcattatct
      901 ccagttaaca ttacaacttc ttttacccct atttctttta agcttcttat ggcattttta
      961 ctatcttctt ttacttcatc agagataact atataacctc tatatacttt atcaacagca
     1021 atatagacta ctgtgcctac ttctttagct gatgaataag atatattttc ttttttcata
     1081 agtttctcat tacctgctaa tataaaattg ccattatgct ttactctaat tccataagct
     1141 gctatttcct cataactgtc tattgtatct aaatcaattt ttttattata gtaacttaat
     1201 atggactttg ctattggatg atttgaattt acctccgcaa tagctgcata ttctaataat
     1261 tcttcttctg atataccttc aggatttaac ttagttacat tgaacacacc tttagtaagt
     1321 gttcctgttt tatcaaatac tactatatct acacttctta aagcttctaa atagttactt
     1381 cctttaataa ggataccatt tttagatgca aacccaattc cactaaaaaa actaagtggt
     1441 attgataaaa ctaatgcaca agggcaagaa acgactaaga atatcaatcc tctatataac
     1501 caatcactaa atacctcacc tgagattaca agtggtggca caaatgctat taataaagca
     1561 gctattacta ctattggagt atagtatctt gaaaacttag atataaagtt ttctgtcttt
     1621 gattttttaa tgctagaatt ttcaacaagg tcaagaatct tagaaactgt tgattctcca
     1681 aaactctttg taacttcaat actcaataaa gcatttttat ttataacacc tgataagatt
     1741 tcatctcctt tttcaacttc tctcagcact gactctcctg tgagtgcaga agtatctaac
     1801 atagaaactc catctactac tacaccatct aatggtactt tttcaccagg ttttactact
     1861 attatatcac ctacatttac ctcttctggt gacaccacct taacttcaga attaactttt
     1921 agatttgcat agtctggtct tatttgcata agtgaagtta tagactttct ggatttacca
     1981 actgcaacac cttgtaaata ctctcctact ttatagaaaa gcataacccc tactgcttct
     2041 gataactccc ctattgttaa tgctcctact gttgctagag ccatcaaaaa gttctcatca
     2101 aatactcttc cttttgatat atttcttatt gctcttaaaa gcacatcacc acctactatt
     2161 acataggcaa ctataaatac tatattgcta aactgacttt cataacctgt agctgtttga
     2221 tatataccaa atatatatac aagtgctcca attataagtg gaattaattc tttcttattt
     2281 gtatcattta cagctcctga tttttcagta gttctccctt ttactttgtc agtagaccct
     2341 acttgtatat caagccctgg ctctgttgaa tttattattt cttttatttt atttataaca
     2401 tcatcctctt caaagttatt acttatattt actgtaagtt ttttatttac aaagtttaaa
     2461 ttagaagatt caacttcttt taatttagaa actttgttat taatctcttc tgcacaatga
     2521 gcacagttta atcctcctaa tataagctct tttttaattg atgttttact agctgcattt
     2581 tctttagaac ttatttgtat atcaagacct ggctctgttg aatctattat atctattatc
     2641 ttttctatag tagtatcctc attaaaactt tcctttatat ttactgtaag ttttttattt
     2701 ataaaattta aattggaaga tttaacttct tgtagtttag aaactttatt attaatctcc
     2761 tctgcacagt gagcacaatt taatcctcct agtataaatt cttttttaat tgaattattt
     2821 gcttccatat atattcactc ctctcattta tcatttataa gtctctctaa tatgatttaa
     2881 tccacaatca aatatctgac ttatatgact atcatctaat gagtaataca ctgtttttcc
     2941 ttctcttcta aactttacta atctagcctg ctttaatact ctaagttgat gagatattgc
     3001 agaatgagtc atatttaata aactcgctat atcacataca cacatttcat ttgcaaataa
     3061 tgcatataat atctttactc tagtagtatc cccaaatact ttaaataatt ctgctaaatc
     3121 atataacatt tcttcatctg gcatagttga tttagcctct gttactattt cttcatgtac
     3181 tatattacaa ttacaatcat ttatctcttc tctcattttt aatcctccat tattttaata
     3241 tatgaataac tgttcatatg ttcattatat gttatcattt ctaaatttgc aacaataatt
     3301 tttattaatt taatataaat agaatgcaca tattataaac ttttttaata tatatattat
     3361 tagaataagt ttttgtaaac ttttttatag ttttctagga ggtgcaagtt taatatgagt
     3421 aacaagaaaa aaaaggattt agatactagt tacatgcctt acttagatcc agcgaactat
     3481 gcagattata ttactaatga agaaattccc caagatgaat tgagaaatga ccctcaaatt
     3541 tctaatggtt atacaaaaat acctaataac cagaacataa ataacctata tcctaataat
     3601 gtaaatcatt atcctaaaag tagtaattct ccaaacaact tgcctaacac aaataataca
     3661 tccggaaata tgaattacaa tacatctgct acaaataata tgcctaataa catgaataat
     3721 aatacgggta tgcctaataa tatgtctaac aatatgaata gtaatatggg tatgcctaac
     3781 aatatgccta ataacatgaa tagtaatatg ggtatgccta acaatatgcc taataatatg
     3841 aatagtaaca tgggcatgcc taacaatgtg cctaataaca tgaatagtaa tatgggtatg
     3901 cctaacaata tgtctaataa tatgaatagt aatatgggca tgcctaacaa tatgtctggc
     3961 aatatgaata acaatatgta tggtaataca ggtatgccta ataacatgaa cagtaatatg
     4021 gggtataata tgaacaatac tatgggtatt cctaacttct catgtaatca aaatatgcct
     4081 cctaatgtac ttatgatgat accaggagtt atatgtcata atacaatgca aggtatgcct
     4141 gtagttatgc ctagtactat gcctcctaat atatatccta ctccttatgg ttctagtaat
     4201 atgtctgtac aaggtatacc acaagctact aatattgagg aatttgatga ggaagaaatg
     4261 taatatatat ttttttaagt aagttgtata aaacattaat aattgaccat aataataaat
     4321 gtattcctca taatattccc ccaatattat tataggtata gaaagttgac tgaatatgcg
     4381 cttattcggt caacagatat taacataatc taataagata aacatagaaa aagtcagata
     4441 aaatttaatt ttatctgact ttttcattta aaaatgctct cttgtgttgg tgattcagaa
     4501 tagtatggta ctcgtatttg agactaatat tggcaaacaa cataaagaaa aatataaatt
     4561 ttttataata aactgtataa aattttaata attgaccaca ataataaatg tattcctcat
     4621 aatattcccc caatattata gaaataaatt taagcgagat taaattcagt taatctcgct
     4681 taaataatgt ctaaatttat tattccaaaa aatcatcaaa atctaatgaa cctgattctg
     4741 caaaatcata taatgcattt tgctcaaaga aaaatttctc ttcaaattta atatagtcgc
     4801 tataattaga ttgacttatt tcattgatat aattgcaatc attttcgtta taagtaccaa
     4861 taaaaaactt atttcccatt aagtaatata tagctttcat atcattattt attatatata
     4921 cattttcttt tacatggtca ttattaaaat taaatctagt aaagaatata ccttcattca
     4981 tattactttt taacagaaat ggattttctc tataaaatac tcctgcaaat tcttcaggtg
     5041 aatttacact gtaaacactt acaaattcac ttttagaaat ctcatcaaat acctcaaaat
     5101 catacatagg ttctttatct gtcactaata gagaattaat tctaaaacca gtttcataac
     5161 acttacttat gcaaaaagca attttacata tataatatcc atcattatct tcatataaag
     5221 cttcacttat atatctgcct tgacctttat cacttaccac gtttttaagt aatgttccat
     5281 ttatattagt aatgtgcata tttgcaatct cgtcacttcc agaaaagtac tttaaacttt
     5341 ctctatccca tgctataaat ctcatggtca tatagtttat aaattcaact tcctcgtcaa
     5401 ctcttttaca tattttattg tataattttt ctatagttaa atctgtttta tagtttttta
     5461 taatatcaat atactcacat ttatctcctg gcaatagctt atcataataa agattcttat
     5521 taccaaaata agatactaaa aataaagatt catccttcgt taattcaact ctatctgaac
     5581 caaatcctcc catcaatctt tcttcttcca tataagcttc ttcttgtgtt gggttattta
     5641 aactcacata atccgctaat cctaatccct ctgcatctaa taaaaaatat tgacaaaagt
     5701 gattgttttc atcatctatc caatttatta taagacctaa actgcccata agtctagaat
     5761 ttgtagcctt tgcaaaatta aaattcatat agtcacatcc tttaaactct aaaatacttg
     5821 ttttttaata tataaattat tatacatata ttttaacaac ttagatacaa tttataatat
     5881 aatataagga aatgattaat tgaggtggtc ttatgaaaaa tatagcagct ttttttgata
     5941 tagatggtac tctttataga gactctctta tggttgaaca ttttaaaaaa ttaattaaat
     6001 acgatataat tgaccaaaaa aattggtata aacatgctag agacactttt atggattggg
     6061 ataaaagaca aggtaattat gatgattatc tattagaaat atgtgacctt tatgttgatt
     6121 cactaaaagg attagataaa acctgtatca actttacaag tgaccaagta attaaattaa
     6181 aagcagatag agtttataaa tacacacgtt caaggattga gtggcatcta aatcaaggac
     6241 acatagttat atttatatct ggtagccctg gatttcttgt tgaaaaaatg gcaaaaaaat
     6301 ataatgtaac cgattttcta ggaagtgatt atgtctttga aaacaatata tttacaggca
     6361 cagttattcc aatgtgggat tctataagta agaataatgc tataaacgat tttgttgtaa
     6421 agtatgattt agatttatca aactcgtatg cctatggaga tactaatggt gatataaata
     6481 tgctaaaaag agttggaaat ccaatagcaa taaatccaac aaaggaactt ttatctcaaa
     6541 tatcacttga tgaggaaatt tctaaaaatg ttgagataat agtagaaaga aaagatatta
     6601 tttattctct atctacagat gtaaatatag tggatattta atttatacta tctattttaa
     6661 aaacttatat tatatctaat atttatatct aacatataaa agctttgact aaaaatcaaa
     6721 gcttttatat gttgcactaa gaatatatta aatttagctt tatgctttaa tgtatattca
     6781 tatatatcat ttacacttat ctaaactaca atttcattaa aattaaatat aaaaatcaac
     6841 tattattttt taaatagcat ctttcttaat ctattattgt aataacctat aaaagaactg
     6901 taaacatagt catatactat aaaggctatc tcaaatgaac ctataataaa tatgtttatt
     6961 ggaatataaa ctattgttct taataaaaaa tacaatataa gtatcattat atttgcaaat
     7021 actaatttca taaaatactc aatatatata gacctatctt tttctataag atattttaca
     7081 ataccatata ttccaaaggt aagtgaatat acaatccatt gagacttact tgccatcact
     7141 ataaatccta aaactataga acctatataa aaagcaattc cactcttaaa gccccattcc
     7201 attattacaa ttgatactaa aagtgatgct aaccccataa taaacaatgt atttacagga
     7261 ataatgtttg taagagtcaa caatatcaca tttaatgcta ataaaactcc tccataagca
     7321 acttttatac tcatatttat catcctaaca acaagttatt aaatctccac caaaacattc
     7381 acaacatgaa tctaaacacc aaagtttagc acaattttca caacaatcgt cacctagaca
     7441 acaacagcaa tcatcacagc aacagcaaca acatccatct aaatcattac gtcttcttct
     7501 attataattg tcagccctat tgctataatc atttctatat tgtgtataac ttctaagtgc
     7561 atcactatat tcactatttt caggctccat aaattttgct ctttttaaga agtcttcacc
     7621 ttcttcataa tatcctatgt tcattgcaga aaaaccagtt aaataatacc actctgcaca
     7681 tttgtcagtc aaagttttta aaaaatcata tgctttttta aattcactat tttctatgaa
     7741 tgatcttgct ctcataaaat tttcattatt ataagtatta ctgtacattc tttccacctc
     7801 tactttctaa tatattaata tatcttaaat aaacaccaga ataaattata ttttctatta
     7861 ttccaacatt tttatttaga tttagattat caattcccct agctaaaaat cctaatgatg
     7921 ttactattat tttttttact ttttctttta actcatcatt tttatcaata tactctataa
     7981 atggattata tcttcctttc ttaaaatctt catctaaatc ttcataggca tctagtagat
     8041 atatatactt acctatatta aaacctatca ttcttaagtt tctctcattt tcatcttttt
     8101 tatagacaaa tacttcaccc attatatttc caaatatact agatacttca tctatattta
     8161 tatttttatc tttttctaac ttatttaatt catttagttg ttgttttata tactctgctt
     8221 tttcaggata cttttcatat gctaatttta atttgttttt atatatataa tatgccaatt
     8281 tatcttttat gcgtttatca tccattaaat tatcttccaa tttataatac gttaaaagaa
     8341 tattcatact tgctgcatat tctgtaatat catttgtaat tacctttttc tttttaaatg
     8401 gatttactat acacacttcc tctgtactta tagactctgg gttatatact gctgttaata
     8461 aaacaattaa aaatgttata tcatagttca aagaaaacct agagatttct ccatgatttc
     8521 tttttaagta tttacatagt ccacaatagt aagctttgta ataatcatat tctctaaatg
     8581 ttaaatccat tttgtttatt ttaacatatc caaacataaa tactcctttt tgtactattt
     8641 tttatttaga ttatatatag tataacactt tttatcaaga ttatataatt tacagtattc
     8701 taagaaactt aaaaaattcc ttctaatcat tgtatcttaa atttaaaata attagaaggt
     8761 tgggttaaaa ataatattaa attatatact tatattaact catacaagtt agttatgctt
     8821 atatcaattt aagttttaaa taattggtat atatttaaaa ctacctacag tatccttcaa
     8881 ttcttttttt gctttgttta taaccaattc atcaagcatt acatcattta ttgaacatga
     8941 tatagattta gatgccaata acattgcttt aaatcccata tcagaacctg cactggcaca
     9001 agattgccat gtatgggcag aaataccaat aggccaaact gaacaagaac actgtgctgt
     9061 aggaattatg tagctaacat ctccaatatc taatgataat gatatacagt tattatgagt
     9121 aaatgtatca tccgtaactt catcatgcag attcatctta gtaatatcct tatttccact
     9181 taatacacta gaaacactac ttcttttatc tatagacact gtctcagcta atttatctgc
     9241 aaaatagtag tcatcttcat tatagttttg cacacctact aatttcatat tttgtgatag
     9301 aatatctgtt aatattgtat ttggaatata gtcatatact ccacttataa tgtcatattc
     9361 cataatagta ccagtcatta atgctgctcc ttttgctata tcaacaatcc taccaaatac
     9421 atctcttaca tgctccattt taactcctct tatgtaatac cacacttctg caaaatcagg
     9481 aactatattt ggcatttttc caccattagt agttacatag tgtactctac aattatcaaa
     9541 tatatgttct ctcaaataat tacaacctat attcataagt tctactgcat caagtgcact
     9601 tcttccgtta taaggagctt gtgctgcatg ggcactaatc ccattatatc taaatttcac
     9661 agagtaatta gcaagtgttg gtattcttat tggagtattt atatcaaatg gatgccaact
     9721 aaaagcacaa tcaattccat caaaaaaacc tttttttatc atcaatactt ttccagataa
     9781 atcttcttct gctggacatc catagtattt tatagtccct ttcagctttt ttagtttgat
     9841 taattccttt actgcaatta cagctcctat tgaacctgta ccaagtaagt tatgtccaca
     9901 tccatgacct gcaccaccat ctacaatagg ttctttagta gtggatactt tttgagacaa
     9961 accatctaaa gcatcatatt ctcccaaaac tgctataact ggtctacctt ctccataact
    10021 agccacaaat gctgtatcca taccttctaa tccctctata ctaaaaccat gtttttttaa
    10081 acattctttt tgtaaatttg aagcatagta ttctttatac tgaagttctg gatttttcca
    10141 tatcttatct gatatatctc ttaattctcc ctgtatctca tctatatatt ccatcaaaaa
    10201 ctttttattt aaattatcca tattaattat ataaacctcc ctgtttctaa taacttatcg
    10261 attatcagcc aaaatgacta attttaactg atttaaaaat attttctacc atacaaccat
    10321 tttatacaat aaaacctctt gacttgtaag tttcatttta tcaagtaaga ggttttcaag
    10381 ttttataaaa tttttagcat gttaaccaat caagcatatt aacccataat ttattatagt
    10441 atttccaatc agtaaattct tttggacccc agtgaggtgc acagtcagaa ctaaagatag
    10501 cagattttcc ttttccaaac tcgccaacag ctacaaatgg gtctcctcca atagttgcta
    10561 aaacaggaca attatctcta gctactgttt tgttatatcc taaaaacttt ggccattctg
    10621 ttggtatacc ttttaatact ggatgttcag agtcaataac ttctggaatt attcctgctg
    10681 gtttttcaac tctatcatct ttatctatca ttgttattgg taatacatct ttgatagcag
    10741 tttctccaaa tctagctttt gcatctattc ctgtaaatga catatatcca cctaccatga
    10801 ttaacgcccc accattattt acatactctt tgattagttc aagtctatct ggattactat
    10861 tgcaatctat aaaagtacta ttagataata agaacgtatt agaacctata tcagataata
    10921 ttatacagtc atactcattt aactcttcta atttatacgg aaaactatct gctgctacat
    10981 gtgcaggcat atgaactgtc tcatatcctc cagattctat tgcttctttc aaccacttta
    11041 cagcttcttc ataatgagtt gtaacaaacg tatcaaaccc ttttatatga gttatatttt
    11101 ttacccaaga ttcccctact attaatactt ttttcattta tatattcctc ctacttttat
    11161 aagtttaata ttagacttgc atacataagt atactatcta aatactcctt aatttcaaca
    11221 tattcatcaa ttgaatgaca ttgttctatt gaacctggcc ctaatataag tgttggtatt
    11281 tcagctaaat ttttcattac tctcgcatca ttgccagctg ttgaaccttt tatctctaat
    11341 ttttttccta gagtttcttc tagtatttta tgtgcattca ctacaaaatc agaatccttg
    11401 tccatctcaa aacctaaccc tgattgatat atgtttatat ttggtttatt atctttaagc
    11461 cataaatctc cattagccct tgtcattatg acatttgtta catcatttac aacttgttca
    11521 taactcatta tatttggcaa gaagtgtaca cataaattaa atacacactt atctggcaca
    11581 gtagaacctg ctgttccacc atttattaca cctaaattta ttgtaggtga aggtaatagt
    11641 ggatgtttat atatcataag ccagttatgt tccaactctt ttatatcttg aagcaacaac
    11701 atagccttct caattgcatt tacaccctcc cacttactac cacagtgaag agacacacct
    11761 ttaacctcaa cttcaaagaa tacaaatccc atatgtgcaa ctattaagtt ttgttctgat
    11821 ggttcacaaa ttatgcaaca atctccatca ataccattca taactgcatt tatggtacca
    11881 tttccgccac cttcttcatc tactactgac attattttta cattaccagg tacatttaga
    11941 ccactatctt ttataagctt tacagctaat attgatgcta taagtccaga tttcatatca
    12001 gcagttccaa gaccataaag ttttccatta tcttctgtag cacgatatgg attatatttc
    12061 cacttactta tatcacccgg tggcatagtg tctacatgac cattaaatac aattgtctta
    12121 ccaggtaaat catcactata cttacaaatt aaattatatc tatcttgata attgtgacct
    12181 agatttcctt ctttatatat attttttgct tttttaatta attcttcgct catttcttgt
    12241 ctatccacac taaaacctat gtaatttgca agtttttcaa tatattcctg tccttctttt
    12301 tcaaatccac ctagtattcc atgaccaaca tcttcagtct ttatacttac aagttctttt
    12361 aaataatcta tgtattcttg ttttttacta tttaatgtat ctaagagaat ttttttcata
    12421 tttcctccta agatttattt ttacatttaa aatttcaagt ctaatctcat ctatttaagc
    12481 catagtaaac tttttcactt agcatattct cattcaatgt ataaagatgt atgcaaatta
    12541 aagtataaaa atatatacaa aaacttaata atttttatag tttataagct aaaatttaat
    12601 tactatttag atttagctga tttttttaat tttatattat ttatccatat agcaaataac
    12661 attaccaaac cttttataat catttgatta tatgaagata cacttaataa gtttaatcca
    12721 tttcctaata ttcctattat tccgacacct atacatgtac ctactataga accagaacca
    12781 cccatcatat tagtaccacc aagcacaacg gctgctatag catccaattc tgctccatct
    12841 ccaacagttg gtgaacctga tgccaaacgt gatgatagta ttatcccagc taatgctgtt
    12901 agtagtccag ctagtgcgta tacttttact ataactttat ttacttttac tccacataat
    12961 ctagcggcct cttcatttcc acctactgca tgtacatgac gtccaaaatt agttcttttt
    13021 aatagaaaat gtcctgctat tacaactata atcataatta taactggtat tggtattggt
    13081 ccaatatatc ctctaccgag catcttaaat gcatctgtat ttactgatat aggtcttcct
    13141 cctgtaaata caaagcttgc cccacttatt atcgttaaca tggctaaagt tacaatgaat
    13201 ggaggtagtt tttgtgttga aataattgca ccttttatga ctcctaatat tgtccctatt
    13261 gctaatgcaa gtatcatacc tacccatata ggtgcattat aattcactac tgttgtagcc
    13321 caaaatgtac ctactaaagc aattactgct cctacactta aatctattcc tcctgtaatt
    13381 attacaaatg tcatacctac tgcaagtatt gcatttattg atatttgtct tccaacatta
    13441 attaaattat ctaaagttaa aaagttagat gaagctacac tcattattat aaaaattatt
    13501 acaagtccta cagctgcact cccttggtct ctaaatacac ttgttaattt tgtcaataat
    13561 ggagaagatt tttcttcttt atgcttagtt attgaactca ttaattttac ctccgaaagc
    13621 caattttaat acattatttt caaccatttc ttcaccttct aaaaatccac ttatatgacc
    13681 ttctctcata accattattc tgtcactcat tgatattaat tctggtattt cagaagatat
    13741 cattattata cttacaccac tctccactaa atctcccatt agattgtata tctctgcctt
    13801 agcatttaca tctatacctc tggttggttc atccataatc aatatatctg gttgtaataa
    13861 aagccatctt gctattatag ctttttgttg gtttccacca cttaaacttt gtataacttg
    13921 attcatatgt ggtgttttta tctttaaagc ttctatgtat ttttctaaaa tctctttttc
    13981 cttttttcta tctataattg atttaaactt agatatcttt tttaacccag ccatagttgt
    14041 attttctttg acactcattt gtaaaaacaa tccagtacct tttctatctt ctgttattaa
    14101 tcctagtcca ttttctattg catctgatgg agttttaaac tttacttctt cattgtttaa
    14161 atatattttt ccagaatcat atgttctaag tccaaatata gcttctacta tttcacttct
    14221 cttacttcca actagtccac ctattcccaa tatttcacct tttcttatat taaagctaat
    14281 atcattaaaa acattgttct tagttagatt ttccactcgc ataatttctt cttttatttc
    14341 tacttttctt tttgggaaaa attggtctag ctttctatct atcattaaat taactaattc
    14401 ttcctcagac gatacatctt tggtatttaa agtcgaaatc gttttcccat ctcgcattat
    14461 agttattctg tcacaaatct caaagagttc ttccatccta tgggatatat atattatact
    14521 aactccactc tcttttaaat catttataag tctaaaaagt atttcagtct cttttttact
    14581 tattgaagaa gtaggttcat ccattattaa tactttagtt tctgatgata aaactcttgc
    14641 tatttctacc atttgttttt gagctatact aagctctttg actaaactat ttggatttat
    14701 atctattccc atattatcga aaatcttttt agcctcttca ttcatttttt tgtcattggt
    14761 taagactttg ccatttattt cttttcccat aaaaatattt tgtgctactg ttaattcgtc
    14821 aaaaactgtt agttcttgat atatggcatt tatacctatc tttttagaga tatctgggga
    14881 tatattctct atttctttgc cttcaaaaat aaattttcca gaagttttcg aatgtgcacc
    14941 agttaaaatc tttatcattg ttgatttacc agcaccattt tcacccagta gtgcatgaac
    15001 ttcgccatga aataactcaa aattaacatt atctaatgct ctgacaccag gaaattcttt
    15061 agcaatatta cttaacttca gaattatatt actcataatg acactccttt ttaaatagga
    15121 tttctttcaa ataatctcat tttattttac taattcttaa agtcttttat attttcctta
    15181 tcataaagta aagctggtac tggtatattc ttttctacct tttccccttt tatagctttt
    15241 actactgctt ctacagctaa acgtcccatc tctttaggtt gttgttgaat catagcaaga
    15301 atagttccat ctgttattcc acttgatgct tcttcagtta agtcaaatcc tacaatctta
    15361 acatccttat tttttgcaga ttcaagtgca gctttagctc ctagtacact attttcagct
    15421 gttgcatata ttatatctac atctggatta gattgaatta agttttctac tgtattaaga
    15481 gattcttctc tgtcatatcc tggttgtgaa tttaatatct taacatttgc tgaacctttt
    15541 aatgcatctt taaatccatc tattctctgc atttgtattt gagattttaa atctgtcact
    15601 attgctattt ctgactttcc acctaacttt tcatctatgt attttttagt gtattcccct
    15661 aattttttac cagcatcata actaactgtt cctacataac ttgtaatatt ttcagtattt
    15721 aatacagcat ctactgtaac tactggcatt ttttcaaatg ctccttctac tgctggtact
    15781 atagccgaat tatcagttcc aagtactatc attccatcta cattttgttg tataaaatct
    15841 tctattgctg atgtttgctt agctacatct tggtctgggt catttactat aactttcaca
    15901 cctaattctt tagctttttc ttttattccc tcatcaatat ctataaaaaa ttgatgttga
    15961 agagttattg tagatactcc aatagttaaa tctttcttgt ctgaaccacc tttattatct
    16021 gatttacttg gtccttccat tgaacaccct gttaacattc ctattgctag tattccagca
    16081 attcctaaag ataaaatttt tctcactctc ataattaacc tccattttta atagttttaa
    16141 atttgaacaa attagatttt tatttattat ttaaatactt ttcaacatct tctttatagg
    16201 gcataccaga ttgtgcacct agtttagtta cagaaagacc tgatactact actgcatatt
    16261 ctactgctgt atataaattt ttcccttctg ttatagccac tgccaatgct ccattaaatg
    16321 tatctcctgc tcctgtggta tcttgaacat caacacttat acaagataca tgcttgattt
    16381 cctcaccatc ataaaatcta gctccatttt ttccttctgt tattacaagt ttatttggat
    16441 atttttttaa tacttcttct atcccttcat ttgtgtcaaa aactatctta tattcatgtt
    16501 catttggtgt taagtaagtt actttttcta ttatatcttc atttagtttt actgctggtg
    16561 ctggatttaa taaaacccta atcctatttt caaaacagaa attcactaca taatttattg
    16621 tttttaatgg aatctctaat tgtagcaata ctatatctgc attctttatc tcttcttcat
    16681 tctttttaat taattctata tctactagct cattagtccc tggtacaaca acaatactat
    16741 tatcattttc acataatgtt ataacagcaa caccagaact tttgtgatta tttctggata
    16801 ctaagctata atcaacttta ttcgttctaa aatttcttat taactcctct cctaagccat
    16861 cttcccctat gcatgatatc atttttacat ttgctcctag tttagaagct gagatagctt
    16921 gattagcccc ttttcctcca ggtgatgtaa aaaaactatt acctaatact gtttctcctt
    16981 tttctggtct tttatctaca gaacatacca tgtccatgtt tacacttcct atgacaacta
    17041 tgtttcccat tacattactc ctttacatat ctatttatgt ctctcgtgct gttattcact
    17101 ttcttttgtt gaatctctta tgaccaattc tggtttgaaa atcaattcat caaacgattc
    17161 ttttttatct cctcttaaac aatttatcaa tatttcactg gctttatatc ctatatcata
    17221 agacggctgt tttactgtgg taagagaagg gcttattaga cttgatgttt gaatatcatc
    17281 aaatcccacg acacttatat catttggtat acttaatcct ctttctttaa gacctcttat
    17341 gacacctatt gcaatcaaat catttgcaca aaatattgca tcaaaatcta tcttttctaa
    17401 attttttata aattcttgtc cccattcaat cttatatttt ccttcaaata cataagcagg
    17461 attgtagctt aaattgcact cgattagagc ctttttatat ccttctaatc tatctactgc
    17521 tatttcattt tgaagtggac cacttaggta tattattttc ttatttccaa tatctaataa
    17581 atgttttgta gctatatagg ccccttcaaa gttatttatt ttaacaattc cttttaaggt
    17641 ttctttgttc atacttatct tcttatcaat caagacagtt ggtattttta tatctttata
    17701 atttgcttct ttccagtttg tatttgaaga tgctgcaaat ataattccat ctatcatcct
    17761 ctctgatagt gttcttattc cttcatattc ttttttagca tcttcatctg tattacataa
    17821 aattatattg tagccttctt cattagcttt atcttctaca cctcttgata catctgtaaa
    17881 gaatggattt cgtatatctg gtataagaag ccctatagta ttagtttttt tagttactaa
    17941 actttgtgct aatttatttg gtacataatt tttttccttc attattttca aaattttttc
    18001 tcttgttgcc tgacttatat tttcatcttt attattaatg acttttgaca cagttgtttt
    18061 agaaacacca gccaattcgc caatttcttt tatagttata ctcaagaagt tcacccccaa
    18121 aatttaggaa accgttttac ttaaccggtt acctagatac tatcacatct ttttttcatt
    18181 tgcaaccatt ttatataaat tttgatattt ttcccttttt tcaaaatatt gcaacttata
    18241 attcaatttt aatatttaaa ttaatctgca aaaaaaaatt aatatacttt tataattatc
    18301 taaaagtata ttaattaatt taagcagtat ttattaaaat tcaaatcctt gctctataat
    18361 cattttttta tcattttcaa tcccacttcc aacagttgtc aaataatcac caacaattgc
    18421 agaatttact cccccattaa atccaacttt gtcatatccc tttaatgata gccttccacc
    18481 agcatacctt atgtacacat taggaattat aaacctaaat actgctgttg tttttagtat
    18541 ttccattggt tctaatacat cataattttc cattggtgta ttcttaatag gatttaaaat
    18601 gtttattgga aatgatttta catttaattc tcgtatttca aaagccattt ttagtctctg
    18661 ttcttcactc tcattcattc caattatacc gcctacacat acatctagcc cagctttttt
    18721 agcatctttt atagttttta tcctatcttt atatgtgtgt gttgtacata tattatgaaa
    18781 attatctcta cacgtctcaa cattgtggtg atatgtagtc acacctgctg acttcaacat
    18841 tttagcttgc tcataatcta taatacctaa agatgcacat aattttaaat tagtattttc
    18901 cctcaatcct tcatagatat ttaaaatatt attaaactcc tttcctgaca tacctttacc
    18961 acttgtaacc aatgagaatc tatgcactcc tttactctcc atctctttag ctctatttaa
    19021 gatttcattg taatctaata atgaatattc ttctacacca gttttataat aagaagactg
    19081 agcacaaaat ttacagtctt cactacattt gccagattta gcattcatta tcgtacataa
    19141 atctgctttt cttcccataa aatattctct tatttcattt gcagatttta atagaatatc
    19201 aaaatcgttt ttattatttg tatcaaggct tattaaatta agagcttctt cataacttat
    19261 ttctttttct ctcaatactt tattttttaa ttttattatg tatttttcca tatatcctcc
    19321 tatttgtcaa cttaatattt ttatgtagtt tacttattat atatagtatt gcatatataa
    19381 catttattgg tcaactttat tttagacaca agtttactat acacaaaaaa atactgcttc
    19441 aaaacaatat tagtatatag attatacata ttattattaa agcagtattt tttattagaa
    19501 tataattctt actggtttat aaaactatcc ttgtcttaac tccatccaag ctttccattg
    19561 taataacttc taagccttca tattctctaa atagccattt taaatccttc atggcttgat
    19621 taacctgact ttttgttaga ttatttataa aatattcttt tctagtttcc tcatactctt
    19681 tgctagtcaa aaagtttctt agaaaattaa acgcaaatac acttggaata ttgtttacat
    19741 tagccttctt gctgttttcc ttctcatagt aaattttcat aaatgcatac tcctttgata
    19801 cttttagatt tctcttacaa taattatatg catttaagtg ctactattct tataatttta
    19861 ttaattcata ttctttactt cccataccca tttcacatgc atagtctatt attctagttc
    19921 catttacatg aggatgttca tgtttgaaaa catcatgacc catttcctta caaatcaaat
    19981 catagcatgc ttgttcaata gctacagggt ctgttgatgc taatattcct atatcatggg
    20041 caattggtct acctgaccaa ggtacacaat cacaaagtgg agttacattc ataacaaaag
    20101 ttatataccc taccttgtct tttttatttg atactgctcc ataagcgtat tctgccatct
    20161 tttcgacaaa cacatctgag tcactttccc attgtatagt tactgctcta gttggacaga
    20221 cagttggaca ttctccacat ccataacata catcagaatc tataactgct tttttatcca
    20281 ctatacttat agcttttgta ggacaagaat taacacactt tccacaacct acacacttct
    20341 tttcctttac tactggagta acatcagaat gttgcatttg ttttcctgct gcacttgcac
    20401 atcccatagc taagtttttt aatgctcctc caaaacctgc tgcttcatga cctttaaaat
    20461 gactcattac tatcattgca gaagaattat aaatttctcc acctattttt acactttcaa
    20521 aatgtttttt gtctattttt acattctcat aatttctact atataatcca tctgcaatta
    20581 ttactggtgc atttacaact gcataagcaa atccattttc tatagcagtt gtaagatggt
    20641 ctacagaatt tgttctactc cctgtataca gtgtatttgt atctgttaaa aatggctttc
    20701 cttcgcagtc tttaacctta tcaaccactt gtctaactgc cacaggactc atatatgtag
    20761 tatttccctt ttctccaaag tgaagtttaa ttgcgacttg gtcatttttt tctattaaat
    20821 ctttgaatcc tgcttcatca aataatcttc ttacattgtt tggtacgttt ttattttgcg
    20881 aatttgagta taaatcacaa aaatatactt ttgacttttc catatctaca cccctttaaa
    20941 atatttactt atactaattt tatcactttt aaagtaattt ttagtatatt ttaacataat
    21001 taaatattct tatatttatt tgatacaaat aatattattt gtattatttt ctacacttaa
    21061 ttctatatat taaactacac ctaaaaatca aaaagacttg aaacttaagt ccaagtcttt
    21121 ttgattttta ggtgtagttt ttaacaacat aagattactt taccttgtga taaaggtatt
    21181 attaaactgg ttttttatta aataaaataa cagctgctag taaacatact atagaaataa
    21241 gaactgttat aataattgga ataataaatt ctggcattgc cactttccct gaaatcaagt
    21301 ctatattttt tgacatcaag aaattaggag tataaggtgc aatctgttta ggaatagaaa
    21361 ttaaactcaa taagagagtt gctaccaata caagtaaaac actggcaaat gctggtctaa
    21421 atagtacaca cccaagaatt aatacactaa tatacataat tcctataagc cataaattaa
    21481 atgctgaaaa tataatatga ttaagatttg cagttggcca aaaatacatt gtatagccat
    21541 aagcaaataa aaaactcaac caaaaaccaa ttgtcataat aatcaccgta acagagaatt
    21601 tagacaatac tatagatgaa cgtgataaac ctttagtcag cataataaca agtgtccctt
    21661 tagaatattc atttgataaa atattacaaa aaataattag agttaaactc ataccaagac
    21721 cagagatatt gctaaaaaat tgtgtccaag aatctaaagc agttggtgca gcagtaactt
    21781 ttaaagtcgg tgcaaaatga gcaatcaagt ctggcataaa ttttgcagaa ataggactac
    21841 ttataccaaa tattagaaat aaaataatta aactaaataa tttataattt cttaaattct
    21901 ctttaaattc tttttttgta aatgctatgt attctctcac tttactacct ccaaaaataa
    21961 attttcaagt gataattcta ttagttccat ctttactgga caaagattca tttctgcgag
    22021 tgtagatata actgtttttt gtattgcttt tatatcttta ccatgcaaaa caatttccat
    22081 attagtttct tctgaatctt ttagtaagga tttaatacca tcactagact taaacttttg
    22141 aatttcatca ttacttgcaa actccagtaa aagtctatcc tttccgtgca tactttttat
    22201 ttctgaaagt gtaccactaa gggcaatgct tcctttgttt aatatagcaa catggtcaca
    22261 gattctttca acatctgata gtatatgtgt tgaaaatatt acagttgttg agtctttgat
    22321 tttaagcata atatctaata tttcttttcg accaacaggg tcaagtgcac ttgttggttc
    22381 atcacaaata agtaatttgg ggcgtgaaag caaagcttga gctataccaa gtcgttgctt
    22441 cattccacga gaaaacccac ctattcgtct cttttcattt ccaagaccca caagtgataa
    22501 caactcttca ctccttatct gtatttcttt ttttgaaagt cccgtaattt caccacaaag
    22561 agaaagatat tcaagtggtc tcatatagtt gtaaaactct ggaacatcag gcagataacc
    22621 tacatgacga ttagaacttg ttttcccata ggtcactttc tcaccacaaa catctatagt
    22681 tccaccatct ggtttaagta acccaagtac cattttcatt gttgtagtct tacctgcacc
    22741 attcttacct acaaacccaa agactgaccc ttctggtaca gtaaaattta aattatctat
    22801 tatctttcga ttaccaaaac cttttgataa tccatttatt gagacaatat tcatcattct
    22861 tcacctcttc ctattgtaaa atacaaaatt ggtcctatta gactaataaa cagtactaca
    22921 ataatccata ttgccttatt tccaatttta taatttggat gtctcaatac atgaacaagt
    22981 gcagtaatta taagtattaa atctaaaata ataacaggaa ccaaaagtgg taagtattcc
    23041 atcaaatttt ccatactctt attcctccaa taaagataat ttttctataa gaaatttgta
    23101 ttctttgttt tcacttaata cagaaaacat tggattattt ttaatagcag caacaatacc
    23161 tgcttttacg attgtatcat cacgtgtaat acctgttcca atttcagaaa tccatctgtc
    23221 aagtttatta aaaaagtcat ccccatgtat tataattggg tatatatcac gtgttgctaa
    23281 atctacatat tttcgtaatg atttaatagc tccttcatta tcaccatgta ttaaattaat
    23341 ttgtgcctgt gttaaatatg aagaaagcat aatagcagga gataatgtat caagctcaaa
    23401 tatatctgaa attgctagaa tacgtctttc tatttccttc atttgtaatt tatctgcatt
    23461 ttgcaaaata cccactagat tttggactaa tgatataagg ttctgatatg caccaagttg
    23521 aaatgtttct cttgcttcat ccatttgacc attcatcatt tgcccttgtg caagaagtat
    23581 agattcattt atcatgggaa aattgctgtt ttgcaataaa tcaatcactt gtatgggttg
    23641 atttaacaat atataacaag ttgcctccat actttttgct tgacggcaaa tatctatgtc
    23701 attacaagtt tcctgtatac gaataaatat ttctaatgct tcactaatta atagttcacg
    23761 ctttttttca tctacaatat catagtgatt aactattaaa agacccatcc gaaaaatcaa
    23821 aggaaaacat gaataatatt tttttatgat ttctcttatt tcatccatga cttcatcaaa
    23881 tggtttaacc gtaaagtctt tgcacagttt attatacagt ttattaatat cttccttcat
    23941 catttgaggt tcataacata ttaactcatc aacggtaatg ttgaaatatg tcgcgagttg
    24001 cggtaaaaag gttatgtcag gatagctttg tccagtttcc catttagata cagaagcttt
    24061 agaaacgcct atataatttg caagttcatc ttgtgtaatt cctttttctt tacgctttaa
    24121 aatcagcgtt tttgcgatgt ttaattcatt catgtcaatc cctccttatg tataattata
    24181 tccttaaaca tgtaaagcta acaagcgatt tgaagttgac ttttgacgaa aaaatcaacc
    24241 acagagaaac aaataaacaa gtatataaaa tatatattta aatttatctt taatctcctt
    24301 tgtaaaatat gtaaactttg taaataaaat ccatattata taaaactaat agttaatcta
    24361 tctaaataca gtttttattt atcacgtttt taaatatttt gtgtaaaacc tcttttaata
    24421 taaacacctt attttcattt ctcatttcat attcttttta aaatactgaa tataactctt
    24481 cgattttcca tttaatcctt ttataaagtt attattcgta tttattcctc taattataac
    24541 aggcaactat catgtattgg tatttgtcta ttatataaaa atctataaaa gaaaagcagt
    24601 caatcattta gattaactgc ttgtacatat atcttattaa actgtataaa ctataatttt
    24661 tattattctc cattttcatc ccaagtcata aatccccatc cactatctgg ataaatatcg
    24721 atagactttt ctctaatcat ataaccaact ttataacact cttttgttat tttattagat
    24781 agtatacatc cttctccatt tatctaattc catttaatta acttttcttt tcaaccttaa
    24841 cttttataaa atcatctttt ttaataattt catacttatt ttctcttcaa catcatcaaa
    24901 tgagggtgtc tcaaaattaa ctttttactt cataaggcac tcttttttgt atgaagtaaa
    24961 atatattttc atcatttcaa caataagtaa gaggcttatc tctattttga gacagcccca
    25021 tttgatggtg ttgaacattt aaataaggtt gaactcgttt tatctctctt tttaagatat
    25081 ctgtaaattt gcacataaag tctcttcttc ttttacaatt ctaatagttt tattaaagcc
    25141 aaagtatata tctccatatt ctttcgtata tgatttattg gtactctttc atctactcca
    25201 tgaccaccag ttttatacgc taagaactta ggtccaaacg ccaccatatc tttaaaccaa
    25261 cttgcatatg tgccaccacc catagcaatt gtatatccat tttcatctgt tacttcttca
    25321 taggcttcta ataatttttt aagtactaaa ttactctcat ccacataatg taagtcttta
    25381 tgagcaataa cctctatttt ccaaccatta caaaaaacct ttttgaatct atctattata
    25441 ttgtttaaaa ctatattttt accatacctt atatctaact cacatacgat tttttcctca
    25501 tttactttta atattcctaa atttaaggta gtgtttttga atacctcatc atattgatta
    25561 atccccaatg catctccata ataatcacta caaaggtatt ttgaaactaa ttctatatct
    25621 tctctatgct gaaaatccat attatcctca actatcttta ttaccatttt agatatagca
    25681 ttttctccct tttcaggatt acttgcatgt acagctactc ctttagtagt taactctgaa
    25741 ataattccat taataatttt tgcagtacaa tgagatggaa caacattttc tttagttcct
    25801 ccacttacta ttatgtaagg tttacttttg tcaattttaa tttctttttc tatccttata
    25861 tgaacccttc ctttttctcc attaaccact ggatacatag catctggagt aaatcccata
    25921 cttggaattt cttcaccttt atctaagtaa tatttgatac atttcatacc tgtctcctca
    25981 tttgtaccaa aaattaatct tattctttta ttaattgtag gatacatatc ctctatgttt
    26041 ttcaatacat gtataagcat agatacagca cccttattat ctatgacacc tcttccataa
    26101 ataatattgt caattactgc tcccgaaaat gggtctacac tccacccctc tcctggtgga
    26161 actatatcta aatgcattgg aatccctatt aattcctctc cctctccaat ttctgcatat
    26221 ccaatataat tatcaatatt tttaacacta aaacctaaac tagcacagta atctaaagtt
    26281 ttatctaaag attttttagg tcctatacca aaaggacatt gtgaaatagg ttcaccttgt
    26341 tgtgaatcaa tttttatcaa ttcttttaga aattctatgg ttctatttaa actattatct
    26401 acacttctgc ttatatccat aaatcaacct actttctatc tttttaaagc ctgtccttga
    26461 agaacaggct tttagcatta aaaattattt ttttgtaaat actaattcac aaacttcatc
    26521 atcatgagca catttttgag caaaatctaa tttaacacct tgtgcacagt caactcttcc
    26581 ataatcccca taacaagcta atctacaaat ttcttttctt tcttctttag ttaatccata
    26641 ttctttccaa gcagcatcta atggacagtg atggaatttt aaaacgccat tctcatctgt
    26701 attttctact aattccattt caaacacttt ttgtccttta ctgttatata acatttctgc
    26761 catttttcct ggagtatctg ctacgttata tttttgacct ctcattttac caaatccata
    26821 tattgcttct ttacatatat catctggatt agctcctaat ttttcagctt ctttcataag
    26881 aagatagaac catactgctc tttctcctgt tgctcctcta attccttcta aatattcctt
    26941 ttctgtatac attttttctg acatttcttt ctcctcctaa aattaaattc tatattttaa
    27001 tcactgtgaa ttagaatatt ccaatgaatg accctaccaa tgctaataca actaaaatta
    27061 ctaataactt agttattgtc cacttcttgt atttcattcc ccaatatacg aagaatacaa
    27121 caccaagtgg taataaacct ggagcaatca tatttaatgt atcttgaaca acaattgctt
    27181 taccaccaat atcaaatgat agcggagttg aaagcttaac tgtagttgca gataatgctc
    27241 ccatcataaa cattcctaga attgaagcac catcaattat cttattgaca ataccacctg
    27301 atagaatttt cttaattgaa tctctaccta aagaatatcc taaatgaaat aagtaataac
    27361 cttcgcaaaa tagtaatata ctaaacatta ttgggaaaaa tgcacctata acacttcctt
    27421 ctgctccaaa tgaagcacct aaagctaaga atattgtttg aaatgtacca aaatctaaag
    27481 tatctccaat tccagccaaa ggtcccataa gaccattctt aacacctgaa ataacttctc
    27541 ctgggatttt tccttcagta gctttctctt cttccatagc taaaactgta ccgtgaatta
    27601 atcctcccca tatagcttga gtattaaaaa attgtaagtg tctctttaac gcatctacta
    27661 aatcttcttt tctcttatat aacttttcta aagccggagt gaaacttgca caaactgcta
    27721 atgcttgcat tctttcaaaa gagttggata attctgctgt ccaccaccat cttagatatg
    27781 tttttgttac atctttcttt gtaagtactc ttgtcttatt aacttcagtt ggaccttgtc
    27841 catttttaac ttctttattt tttatttctt gcattatact tcacctaccc ttttgtcttc
    27901 tttcataaag gtaattaaaa gagctataca aacaccaaat attgcagctg cagtaattga
    27961 tatttcaaaa tattgaacca taaaaaatcc tataataaac attggtaaaa atttattttt
    28021 acctatagta aatattgttg ttgcaaaacc taatgcaggt aatataccgc ccattactgt
    28081 taatccattc attaaccatt gtggtataac atctaataat gattgaacta aatctgctcc
    28141 aaaaaagtta catacaaaaa ctattggaaa ccttaaaaca aacccaaata ttaaagaata
    28201 aagtgttgca catctccaga tgccttttgt attaccttct tcagcatact tatctgcctt
    28261 atgaaccaat acagcattac cagttcttct taagttatta actaatactc ctataacacc
    28321 taaaggtacc gcaatagata ctgcaacttc tgcattaaca ccagtttgaa gtgctactgg
    28381 tattgcaata agagcagcta gacatttatc tgatggaata tttccccctg ctgcgaccat
    28441 tcctagataa accatttcta tacttgcacc aacaatcata ccagttgtta catcacccca
    28501 aagtaatcca aggctaaaac ctataaataa aggagacttt agtgttgaga aaagggtata
    28561 ccctgcaaga cctgctgcaa accaatacca taatcctgtt acaattgcca acatcaaaac
    28621 agattccatt tataattcct cctaatttat attttttatt taaatttctt taacgcattt
    28681 tcatatgtca tagatgattc ctctggtata acttgtagga ctatttcaac cccattttca
    28741 ttaagttcat taagttgttc tacatcctca tttcctaatg aaacagctgt aaacaccatt
    28801 ttctttcctg cttcatttgg aatacctcct aattgaatct tttcatattt aagtccagct
    28861 ttataagcct tatttgccat atcaacattt ttaaatagaa taaatatatt tttatctcct
    28921 aaagtgttgt tttggaatgc ttgtcccgca tcttctgctg ttaaaataac tacttctact
    28981 cctgatggtg ctgccatttt atatatgtca gccataaatt catcttgacc taagaagtca
    29041 tcaactatta ttattttttg agcttgagcg atttttaccc attttgttat aacttgccca
    29101 tgaattaatc tgtggtctac tcttactaat gttatttttg ccattatatt cacctcataa
    29161 tttatatttt tttaaattct ttaattaaat ccacacaaag gttattattt tttttgacga
    29221 ttctttctgg taatgtatgt aatttatctt ctttgcttaa ttcttcatct acgattaaaa
    29281 ttgtctgtaa gctaagtcca tttattgcat ctattcctct tcttatagca acagctattg
    29341 caacacttga tgtagatcct ccatataaat ctgatattat aattttcaca tcttctttat
    29401 ctactacttc ttcaacctct ttcataaata cagaaacatc tttttcagaa cttagtgata
    29461 aaacttcata ttgatttgac aatccaaagt ttttatttgt ttcttctact aagacttttc
    29521 cccaagttcc atggcacagt atgattacct tatatttatt cattgctaaa taaactctcc
    29581 tttatagcga ttaatatttt ggtttaattc tacttcttct tcatcaggta ccatttgaat
    29641 tgatacatta atattctttt taataaattc atctattaaa agaaactctt ttttattaat
    29701 gtatacattt tgagatattt tcttttttcc tattcctgta ggtattcttc caacaataag
    29761 ttttttgata ttaatccctt cttctatcat tctatttgca gtatctaaat ttttaattaa
    29821 tacaaaaacg ttatcatcag cttgattatt ataaaaatat ctccttgatt cacttacagt
    29881 taatattgat aaatcaatat tctttggtgc tgccattttt atcaaacctt tagcaataac
    29941 atcattggtt gtttcatcat ctactactac tatctttttt acacctagat gcttaaccca
    30001 tttatatata acttgaccat gtattaatct atcatcacat ctgcaatatt ttactaaaga
    30061 catttttaat caaactcctt tttctattac attgagctaa gaactttatt aatattgttt
    30121 ataccagttt gtcctgcttc aatacatgct tctgctaact cttctaaact ttttccctct
    30181 ctattaatta aagcttcaag tagcattgga agatttactc cagtaagtgc atgaaacttg
    30241 ccaccttttt taaggtttaa acttgcaaca ttacttggcg aacctcctaa taggtcagct
    30301 aatactaaaa ctccgtcacc ttcatctaat tcatttaact tttctacaaa atttttattt
    30361 aagtcttcaa tattatcatt cctatttagt ttaattgctg ctgttctttc tgctggtcct
    30421 gcaataagtt cacagctttt tataatttct tcactaaaac tcccatgagt cataactatt
    30481 attcctatca ccaatttcac ctcacttttc ttgtcacttt ttatataagc aattgccgtg
    30541 ccaacttatg tgtatcaata acaaatggct attttacagg atttaatcaa aactttttac
    30601 tcaatttttt ttaaaaactt attatttcga tatgtatcaa aagatttttt caacctgtat
    30661 caaatctgta tcaaaaaaag taaaaaaaag atagcctttt ggctattttt aaattttgta
    30721 tcaacttttg aatttatctg tatcatattg tgattcaaat atatctaata tatttgcata
    30781 ttccatatct gaaataatta tatcgaatgt ctcttctact agcttaaaac tttcttttat
    30841 aactaaatat aattctttat ttctactaat tctttcttca tatgatttat aaactaaaga
    30901 ctcttttatt attactcttt caatcataca tgaacaatga aatataaact ttactaaaag
    30961 ttcatcttga attactaaag aatagtgttc actaattcta ttaattactt cttttaatat
    31021 aaaataagcc ttttccccat ttaaaaaagt caaagtttta ctaatattat caattagtaa
    31081 tctatcaaaa tatctaccac cattatcttt ttcagcatat gtaacttcca tatctccata
    31141 atgtttcttt atagattcta taatattaaa atataatttc tctaatgtca tttctggagt
    31201 tagagccttt ctagttgctt ctattacaat aggtgtactt accatatcta ttgcttttac
    31261 ttcttttcct gtagcatcac gaataacttt agcaaatgtt aaaatagacc ccatatcagt
    31321 taaaattaaa attccttttc ctttatcaat tttattggct atttctacag cttgtactaa
    31381 aatatcctga actctatctt ctaatcccat attaattgcc actgcatggt tacaatccag
    31441 taaagtattg gctacattca ccatgctaga tgctgtagat tcaccatgca ttatgactaa
    31501 tattgctata ctctcctcat ttaatcccac atacgataaa taaagaaatg ttgctaaaaa
    31561 aattgcttca tcttctggaa actctactcc atacattaat gacatgttag ataatatttc
    31621 ttttgctatg ttatattcat atgctctttc cttcataatt tcatctttat taggatgctt
    31681 tactatattt ccaatcttta ttctttcaat taaattctga atatgtaaag ctatagcttt
    31741 tattaattta tctaatcctt ctcttttgct ccatttatca tgcttttgta aaatatattt
    31801 tacagtagtt gcaattgaat cattaacaat gttgttataa gctgtttgat tactactatt
    31861 atatataaaa gtattcatta aattatagga atacttctgt atgtctccat ctataacact
    31921 tctaatttgt gactctttaa taccttcttg ttgaagttta ttccaagttt cttttatcat
    31981 tccataaaaa tctaaatcat attttttatt ttctattaat aaattttcac tttcaaaatc
    32041 cttttcttct ggtaaaaaaa taatatcatc ttttccaata aaactgaaat tttgtacaaa
    32101 ctcctctttt ctattatttc catataatga ttctctaata ttatttggta gaagagagag
    32161 ccttacatat acacattccc ttttataggt catataatct aaaaaagctc ttgcacaaat
    32221 taattgtata tcgcttttta attggcctat gtttccctta cacttatata aaataaatgc
    32281 cttaataact tcttttgaaa cctttaactt aacaccaatc ctaacactct cttctttaaa
    32341 aaaataacat ataagcttca ttctctcttg aaagcctctt tcctctaaag acggaatctt
    32401 tatagttaca ggtattcttc ttaaaaacgt ttccaacatt gctgtttctg ggtcttctgt
    32461 agtggctgca attatcataa ctctacactc gtgtacctta ttagcctctc ctaaccttct
    32521 atatatccct ttatccataa gcagaaatag catttcttgt ccctctgcag ataatctatg
    32581 aacttcatct aaaaacaata ctccattatt agcttcatgt acaataccat acttatcttt
    32641 atcagctcca gtaaatgctc cttttacata tccaaaaagc tgcgctaata ataattgctg
    32701 attatcagaa taatcagcac agttaaatat gataaatggt gcattatcac tatcttcttt
    32761 tatagttaaa ctatacttat acatatattc tgcaaatata gatttaccaa ctcctgtagg
    32821 tcctattatt aatgtactca accccttagg tggatatatt actgctgctt tagcctgttc
    32881 tatttgggac cttaaacttc catcacatcc tactaaatta aaaatattgt tctctttttt
    32941 tatactctct aaaatatact catctttgat agaatcattt tcactatatt cgtttataga
    33001 gttaatatta tcaaatatcc ctttatttag tttctttcct aaaatactct caatactttc
    33061 tttatataag tactgaacag gcttaccctt tatctttata ataatacttt cttttattaa
    33121 ttgatttaat tccttactag cattacttct atttatacct acttcagtag ctatatattc
    33181 tgcatcaaat ccaaatctaa tgccattatt aaagttcaag tgttcttctg ttaacctttt
    33241 caagcaaatt aaaacttttt ctttccttga tagcttcttt tgtgtcatag ttaacctccc
    33301 ctataagcag taatactgtt aaacatttat tattaagctt aattctacaa tattttaata
    33361 tttttgtcta attatgtaac tattgatttt ctttcctatt cgttttataa tataaattac
    33421 gttaccctca tcttttatag aggaggaatt tatatgaatt ttttatcaga tttacacacc
    33481 cactctatag tcagtggtca tggctatagc actttactag aaaatattaa ttattgtaaa
    33541 gaaaatggaa ttaagatact aggtacatct gaacatggtc ctaagatgcc tggttctccc
    33601 cacaaatggt actttcacaa cattcaaaat atcccaagaa tcataaataa cattataatt
    33661 ttaagaggct gtgaagcaaa tatactagat attaaaggaa acatagacct agagcctttt
    33721 gtaattcctc ggttagatta tcttatcttg tcatttcacg aagctgtgtt ttctccaaat
    33781 acattagaga ataatactaa agctttaata aatgcaataa ataagcatga taatattgaa
    33841 atattaggac accttggaaa ctcaaactac ccaatcgact atgaattaat cattaaatta
    33901 gctatagaaa agaatatctt aatagaaata aataattgtt ctattaaagg cgtgtcaaga
    33961 aatggtagct cggataactg taagtatatt gctacacttt gcaaaaaata tggtgctaaa
    34021 atcatactga cttcagatgc tcacatttgt tttgacatag gtaactatga gtattctgaa
    34081 aatatcttaa aggaaattaa ttttccagat gaattaataa tgaattatcc taaaaaactt
    34141 attaatcatt ttcaccaaaa aggtaaatta ctagatgttg attatacaaa tatctaagta
    34201 ataatacatg cttactttaa ctcccataaa aattttaata ctatttatat tatatgaaat
    34261 aaagaaatta taataaagaa gctatttaat aaagcttaat tacttttatg aacttgatgg
    34321 attgatatgg tctatgatag caatagaaat tataacattt ttaataaact tagttttata
    34381 taccttatag tataaatcta aaaaagcatc atctaaaaag gagctgtcac atgagcaaat
    34441 taaatttgtt ctatgatagc tcttttttta cttattttaa ttaggtatat ttttaattat
    34501 tttatataaa gcttatgttc taagtaaaat tatgcataac aaacaaaggt ataaaaatac
    34561 cattttttca gataatattt aattataaat aataaattta gaatacttct tttaaatgat
    34621 gagagtctag aaatttttat gtgtattctt taaataaaaa tttccagact ctagcccctt
    34681 tttgaatatt ttaaaattta acttaaacta agcaaattct ataatagctt atctctaaat
    34741 atttaaattt aatttatcat a
//
LOCUS       DAMKNB010000037        31707 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.039, whole genome shotgun sequence.
ACCESSION   DAMKNB010000037 DAMKNB010000000
VERSION     DAMKNB010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 31707)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31707)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31707
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.039"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            134..1300
                     /locus_tag="PC494_002000"
     CDS             134..1300
                     /locus_tag="PC494_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cellulase family glycosylhydrolase"
                     /protein_id="HDF3912501.1"
                     /translation="MYIKGVNLGGWLVLEKWMTSSLFEGTEAEDEYYLPRQLSREAYE
                     SRIKTHRSEYITERDFATIKSMGFNSVRIPVPYFIFGDCEPFIGCVKELDKAFAWADK
                     YGLSILIDLHTVPGSQNGFDNGGISGICSWSQNPEYVAFTLNVLERLAKRYGMRHELY
                     GIQILNEPITERMWNIMNVPNRFKAVDKEMARGSKPNSLEFLRDFYIKAYKVMRPYMR
                     EENVIVFHDAFELKAWKDFMREEEFKNVVLDTHQYLMLAEADGCEQSIDSYLKYIREN
                     YAKDILQMQKYFPVICGEWSLFNSYACGIDTNGGQSPLNGIESNIDKLSKDDKRELYR
                     KIAKAQLDAWRNGSGHYYWNYKLLLDTVNEEGWIGWDSWDLGKCVAQEWYPIEY"
     gene            1322..2968
                     /locus_tag="PC494_002001"
     CDS             1322..2968
                     /locus_tag="PC494_002001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 43 protein"
                     /protein_id="HDF3912502.1"
                     /translation="MIKNPILPGFNPDPCICRKGDDYYLVVSSFEWFPGIPVYHSKDL
                     KNWELYTHILTDETKIDLKKLPSSKGIWAPCLTYCEEEDLFYIVYGIMNSMNARYFDV
                     DNYLITSKDIKGEWSEPVYLHSSGFDASIFHDDDGKKWIASLDWETREGYEKPGVICL
                     VEYCTKKKEIVGYPKRIWSGGTDRGCIEAPHITKRGDYYYIMCAEGGTGYGHSVTMGR
                     AKNIWGPYEKDSMNPIVTSIPGDFYERHDPDHLKPKYYNPESKLQKSGHGSYIETTSG
                     EVYLVHLTSRPFVPELRCTLGRETAIQKMKWTKDNWLRMEDESNLAKEYVSESKLEEH
                     LVSSIPSFDDFDSNELGLQYYAPRISPLSFADVKSRPGYVRIRGQESRTSLNKVSILA
                     RKLTSVYARITTKMEFYPEVHQHSAGLIMYYDNMNYINLRKYYSETLGQSALSIIHLE
                     NGEKTEFLNTRIPIKDIPIYLRLYIQGRKSYFEWSYDEKNYQRIGKVFDTTKFSDEYC
                     KYGEFTGTFIGLTCADRVKHKHYADFDFFEYIVDESKDVD"
     gene            3065..4438
                     /locus_tag="PC494_002002"
     CDS             3065..4438
                     /locus_tag="PC494_002002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDF3912503.1"
                     /translation="MNTEVNVKATTIKYEKISFFERISYGCGDLGCNIIYSAMSAFLL
                     FYYTNYADVSAAAVGSIMLVSRILDGFSDLTMGIIVDRTKSKYGKARPWILRMAIPFA
                     IAAVLLFSVPSNLGITSKLIYIFITYNLVSTVIYTAINVPYATLNSLITQNQYERGVL
                     SIFRMILATCGTLLINGLTLPLVEYFGNNLSAWTKTFFVFGIASIMVFFITFTGTKER
                     VKAVKQDRNEVIPFKIGIKSLFRNKYWIQITLCLVCIFIVFAINGGSSVYYAKFILGD
                     EKLFGPINMVSNISQIIAMFMVAPFIKKFGKRNVLIVGSIILISSNVMFIIVGQNHIG
                     VIFASAIKGIGSAGIASTMFAIVSDTIEYGEWKTGYRTEGLINSASSFGFKVGNGLGS
                     AILGAVLSIGGYVGTSATQSDLAIVSIKVCFIYLPIFITILQIIIMSFYKLDKEYSTI
                     LNELNTK"
     gene            4883..5836
                     /locus_tag="PC494_002003"
     CDS             4883..5836
                     /locus_tag="PC494_002003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding transcriptional regulator"
                     /protein_id="HDF3912504.1"
                     /translation="MKKIGDLRLMMKCCSLYYEDNLNQQEIANQLGISRPTISRILKE
                     AFEQGIVKIQIVDVLKNDYQKIERSLERKYKLKEVIVVDDKQDALTQKQELARAVSEY
                     LTRVVKENDIIGVSIGTTLKEIPRYVEKSNCKNVTFIPLLGGIGDNEIDIHANQIAVS
                     LARAFGGDFKLLHAPAVMSDLSTKEKLCKDEKIKEVLDLIDKTTIAIVGIGNPMSLNS
                     TIMASGYMNEADIEDLKKYNSIGAICLQAFDKEGKTSILEFNQRVLGVKLEDLKKIKR
                     TIGVASGDEKIEAIKASLKAKFINSLAINHSLALKLLEDCD"
     gene            5874..6836
                     /locus_tag="PC494_002004"
     CDS             5874..6836
                     /locus_tag="PC494_002004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-dependent dehydrogenase
                     E1 component subunit alpha"
                     /protein_id="HDF3912505.1"
                     /translation="MSISKETLLEMYKRMNQARKFEEKVSWFFARGMVHGTTHLSVGQ
                     EASSVAAVMALEKGDLVSLTHRGHSQFIGMGIDLNKMMAELMGKETGFCKGKGGSMHI
                     ADIESGNLGANGVVGGGLTIAPGAALTQQYKKTGKIVLCSFGDGASNEGTFHEGINLS
                     SIWKLPIIFYCENNLYGMSTSIKRHMNIESIATRAASYGIEGISIDGYNPIEVYETVQ
                     KAAEKCRRGEGPVLIESRTYRWLGHSKSDANVYRTKEEIESWKAKDPIEFLKNYLIEN
                     NLSNEDELDKIQEFAKQSIEDAVEFAQNSPNPKIESLLEDVYAD"
     gene            6861..7847
                     /locus_tag="PC494_002005"
     CDS             6861..7847
                     /locus_tag="PC494_002005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HDF3912506.1"
                     /translation="MSTRELTYAQAIKEAMSEEMRRDENVIFMGEDIGIYGGAFGVSV
                     GMIDEFGPERVRDTPISEAAIAGAAAGAAATGLRPIMEVMFMDFVTISMDAIVNQAAK
                     MRYMFGGKAQVPMVVRCPGGSGTGSAEQHSQSLEAWFCHVPGVKVVAPSTPADAKGLL
                     KAAIRDNNPVIFVENKLLYRKKGFVPEDDYVIEIGKADIKREGTDVTVITYGRMLQSV
                     KEAAETLSKENINVEIIDLRTLYPLDKETIVKSVCKTGRVLICHEAAKTGGLGGEISA
                     LITESESFDYLDAPVKRICGKDVPIPYNPELEKAVVPRVDEIEEAIKSLIVR"
     gene            7860..8906
                     /locus_tag="PC494_002006"
     CDS             7860..8906
                     /locus_tag="PC494_002006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxo acid dehydrogenase subunit E2"
                     /protein_id="HDF3912507.1"
                     /translation="MVANKIKATPAARSQARKDNIKLDRLIGSGENGRIHLVDVLNYL
                     KDNKANTTPLARRIAEDLNIDLETIVGTGYNGKIRKCDVEKLTAKETIVSTNTSKSSE
                     KKELKIENENSSMFNTVEGIFEKPNPMRATVAKRMSESYFSAPVFTFNIEVDATELKV
                     LRAKLIDTVKESTGVKLTMTDLIVMAVSKILPNHQALNSAWTDEGIFRYKDVNIAIAV
                     GLDEGLYVPVVKNANKKSLKEIAKESKELAEKVKTGKLMPADQEGNTFTISNVGMYGI
                     TTFTPIINMPSSAILGVGATQDKFVPVNGEAKIKPIMNLSLTSDHRVIDGTVAAKFLK
                     DLKELLENPLSMLV"
     gene            9073..10803
                     /gene="lpdA"
                     /locus_tag="PC494_002007"
     CDS             9073..10803
                     /gene="lpdA"
                     /locus_tag="PC494_002007"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HDF3912508.1"
                     /translation="MSVEVIMPKAGVAMEEGTIVSWLKQEGEEVKIGEPILEITTDKV
                     NMEIESEGEGTLAVIIHKEEGEVLPVFTVIGVIAEKGENQEEVKAKYLSGNVSKEDTV
                     KENQNIEVKEEKINKKECNHDYDVVVIGGGPGGYLSALKAALLGGRVALVEENILGGT
                     CLNRGCIPTKTYIKTAEILEEIDQLSKRGVKVTVDKEQDIKKAIKYKNRVVKKLTAGV
                     GGLLKSRDVDVFNLKASVKEEHKVILSDGKVLDTENIIIATGSKVRILPIKGIESNLI
                     ITSTEALDLETVPEELVIIGGGVIGCEFAEIFNSRGSKVTIVEMEDRVIPRMDKELSE
                     SLKYSLSKKGINVLTKKKVSEFKEEGNNILVCIEGEEPIKADLCLYAIGREANLSGIE
                     DLDIKIDKGSIVVNSKMETSMPSIYAVGDVTGGVMLAHAAFKMGEVAASNALGVNKEV
                     DLGALPSCVYTIPEVAAVGITEEDARKKYNVKVGKFNFAGNGRALASGQEQGYVKVVA
                     DAKYGEILGIHMFGCGVAELINHAASFKALEIPTDEASELIFGHPCTSEALMEALADV
                     NGECLHLPKK"
     gene            11221..14169
                     /locus_tag="PC494_002008"
     CDS             11221..14169
                     /locus_tag="PC494_002008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDF3912509.1"
                     /translation="MRQRIKNLIENEDKKNPLTDEVISSRLNIRREDVTFLRNELKIE
                     DSRQRRKVVLIKAIKDILKEEKTINKNDITRRLNSIGFTVSRFTVIQYLKEIQDSGDL
                     KLDKESDDKKEEIINNRENKDIAFDKLIGSSGSLSTIIKLAKAAILYPPHGLHTIIMG
                     PTGVGKSELAECMYKFAVESSRFPKNAPFIVFNAADYSENPQLLLSQLFGHVKGAFTG
                     ADENKEGLVSKADGGILFIDEIHRLPHEGQEILFQLIDKGMVRKLGETRLTHKIDVMI
                     ISATSEPIDSHLLNTFKRRIPVTIEIPELVARPLNERFDIINNFFLIEAQRMGANIHI
                     KSDVLKALMLYDCIGNVGQLRSDIQVACARGLLNQLTNKLKEVNISISDVPGYVKQGL
                     IKIRNCRGKIENYVDGDLIIDSNLQGEIEKKNEDIYTFPDEIYKLTERRHIDLLEQGL
                     DFDVINRIIGGELESCIQKYIKQVKKVSISNNLPDISPIVGKYIVELTYEVIKIASQY
                     LSSLEPNLHLCLAVHLKAAFERLKEGKVISNAHLKEIIGNYPVEYSVAEKVAQYLKER
                     YNINLPKEEIGIIAIYFKMSSRRDMSEQKKIGVLLMAHGRVASSVCEVTNKLLGINHA
                     RYLDMPFEKKPEEMIEEATTIIKDIDEGRGVIILVDMGSLSYFGDIISGKTGINIRTI
                     SRFDTLLSIEVIRRAVLPDLTIDEIVDEVKGIEPQVKEKVSKCNNTKVDFRKPIILTL
                     CITGLGGACKIKKILEENIKSITEKVDIEPIGMIEYPSLDLEIKQISNDKNVIAIVGT
                     IDPQIANIPFFSLVDINDKAKLNQINNLIDTNQIGETNKKYELSDLIHKEDIFVDLQV
                     KSKEEVLKYMSKKLREKGYVTKNFYKKVVERDNLFPTELSDEIAIPHTDGIDVIRPAI
                     SIAILKKPIVWSKSKVKIILLLAVDQKCFNPLSTLLSFIETDEFKKIKNIKDRDFIRE
                     MILDGVNENN"
     gene            14147..14611
                     /locus_tag="PC494_002009"
     CDS             14147..14611
                     /locus_tag="PC494_002009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDF3912510.1"
                     /translation="MESMKIISSNLIFKNIEVSNNEDALKFLGQRLFDEQYVKESYIQ
                     AVVAREKKYATGLPTEIYGVAIPHTDIVHVNEPGIAIGILNKPVKFIMMGTDDTEIDV
                     KVVFMLAVKEPQEQLQLLEKLMTIFQDKNILNNIVDLSEESVSDLLNSKLKN"
     gene            14724..15026
                     /locus_tag="PC494_002010"
     CDS             14724..15026
                     /locus_tag="PC494_002010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDF3912511.1"
                     /translation="MGVTNVAKKILVACGTGVCTSTIAINKLKKALQDIGKLDMVNIT
                     QCKVVEVASKAPDYDLIICTTQVSSSIKTPVINGLPFLTGVGMDKLINDVLEELEL"
     gene            15088..16452
                     /locus_tag="PC494_002011"
     CDS             15088..16452
                     /locus_tag="PC494_002011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425524.1"
                     /note="with GatAB forms a phosphoenolpyruvate-dependent
                     sugar phosphotransferase transporter for galactitol;
                     subunit IIC forms the translocation channel and contains
                     the substrate binding site; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HDF3912512.1"
                     /translation="MEGLYMEILNFIVGLGAQVMMPIIICIFGLILGTKLGKSLRAGL
                     TVGVGFIGLNTIIALLTDNLGPATQQMVKNLGLSLSIIDVGWPAASAIAFASTVGALI
                     IPIGLVVNIVMLITNTTQTVDVDIWDYWHFAFTGALVAGATQSVMWGVFAAVANMVIV
                     LVMADLTAPGIEEYLGMPGISLPHGFTQAFVPIAIVVNKLLDLIPGINKIEINADTLQ
                     KKFGLFGEPLIMGSVIGVIIGIAAKYDIKGILQLGVTMGAVLILIPKMAALLMEGLLP
                     VSEAAQEFIEKRFKNRGKIYIGLDSAVGIGHPVTLSVALVLVPLTILIAAILPGNKVL
                     PFADLAVIPFALVLIVPITKGNVFRTLIIGIIIITSGLLIATNLAPLFTQMALNASFK
                     MPEGATMISSICDGANPLSWVFVKVMNYKVIGGVVFGVIALGMAIYNRNRIINENKKL
                     SIEE"
     gene            16487..16960
                     /locus_tag="PC494_002012"
     CDS             16487..16960
                     /locus_tag="PC494_002012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3912513.1"
                     /translation="MKKYKYDSKRYLLSVTIPGFFMILILIYALFNNYTNFNLNIYSL
                     LIIVCTYSIFNTFISSSNPKKIIIDSKCIHFTSFMTTHKYELKDIEKIRIREFYNKKI
                     YLKINDGNLFKGRYWIRTNMFNNSIALYSYFIELEECLYPDSLKFRNKKFENKNI"
     gene            17132..17782
                     /locus_tag="PC494_002013"
     CDS             17132..17782
                     /locus_tag="PC494_002013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II aldolase/adducin family protein"
                     /protein_id="HDF3912514.1"
                     /translation="MLLEKLRKEVLQASLDLLNYNLVTLTGGNVSGRDEQTGYIAITP
                     SGMDYRNLTPSDIVIVDVDGNIIDGKWKASVDLSDHLYIYKHREDINSIIHTHSTYSS
                     CFAILNEPIECASTTLANEVGGSVPVAKFSPPTSKKMGKCVIEAIGDKRACLLANHGV
                     IAVGPSVGHALTAAVMLEDSAKVYYLAKSIGTPVLLPDEEIQRARDVFFNVYGQDK"
     gene            17956..18888
                     /locus_tag="PC494_002014"
     CDS             17956..18888
                     /locus_tag="PC494_002014"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HDF3912515.1"
                     /translation="MYYLLNKSTNPYFNLALEEYLFLNDKYNDDIIIIWRNEESIFIG
                     KNQNPYQEVYHDVIEKGEIPILRRISGGGTVYHDLGNINMSFIQKDRQLHEIDFLEHT
                     KFMQKMLSTLGLDVSITERKDLFLNGKKISGSAQSIKRKNSLYHGTLLYDSDLNKLTK
                     YLNSNKATESNATKSVSSKVTNIKFLLEKDINYFLDYCVEYLKSNIKNIKELELDEED
                     IKSVYNIGEDKYKKIEWTYGKTPKFQVVLPFNNESKINIHVNRWKVSKFFISYDDNVI
                     NMDKLLDLNFFKEEIKESILENYPHYIDLINLIF"
     gene            19162..19875
                     /gene="ispD"
                     /locus_tag="PC494_002015"
     CDS             19162..19875
                     /gene="ispD"
                     /locus_tag="PC494_002015"
                     /EC_number="2.7.7.60"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 4-phosphate
                     cytidylyltransferase"
                     /protein_id="HDF3912516.1"
                     /translation="MYSVIIVAAGSGRRMNLDINKQFIKLREKEIIAHTIQVFYENIN
                     IDEIVVCIKKEEEDFFKENIINKYNFKNIKIAYGGKERQDSIYNGLKKLDKNCDIVLI
                     HDGARPFVDHRIINESIKVAKEKKAVVVGVPVSDTIKIVSDGTVKETPERNLLWAAQT
                     PQTFEYNLIIDAYEQAYKNNYYGTDDSMLVENIGQSVTMVMGSYENIKITSPEDLNIA
                     EQILNMEKRDEVNSRRRII"
     gene            19872..20357
                     /locus_tag="PC494_002016"
     CDS             19872..20357
                     /locus_tag="PC494_002016"
                     /EC_number="4.6.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 2,4-cyclodiphosphate
                     synthase"
                     /protein_id="HDF3912517.1"
                     /translation="MRIGLGYDVHKLTEDRKLIIGGVEIPHDKGLLGHSDADVLIHAI
                     MDSILGALALGDIGKHFPDTDEEYKGADSMKLLEHVYNLITSKGYKIGNIDSTIIAQS
                     PKMAPYIESMRSNISKVLNTDIDNINIKATTEEGLGFTGAKQGIASQSICLLLLTSQN
                     N"
     misc_binding    20452..20660
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            20724..22439
                     /locus_tag="PC494_002017"
     CDS             20724..22439
                     /locus_tag="PC494_002017"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HDF3912518.1"
                     /translation="MKMSKMFMPTLKEIPADAEITSHQLMVRSGMIKKMTSGVYNQLP
                     MGLRVFKKIEQIIREELNKKDCQEILCAALLPSELWKESGRWTAMGEEMFRLKDRTER
                     EYCLGPTHEEAFTDIIRQEITSYKQLPLNLYQIQVKYRDERRPRFGVMRTKTFTMKDA
                     YSFDVDDKGLDKSYQDMFDAYVSIFNRCGLENSPVQADSGAIGGSTSAEFMVKSEVGE
                     DEVVFCSGCDYAANVERAESCNLASQKEEMKELEEVHTPGAATIKELEEFLKTSPDKF
                     AKTLVYEADGKTVVVVVRGDREVNEIKVSNAIGSVIEFALATDDVVRKVTNAEVGFAG
                     PIGINADYVFIDKEIVEQRNIVVGANKTEYHIKNANYGRDFEGIVGDFRNVQEGDKCI
                     VCGKPLEIARGVEVGHIFKLGTKYSESMNANFIDKDGKSKPIVMGCYGIGVERTAAAI
                     IEQHNDEKGIIWPLSVAPYHVVIVPANMKNEEQISIAENIYNDLQAMGVEVLLDDRDE
                     RIGVKFNDSELIGIPMRITVGKNINEGKVEFKLRHKEDKEIIDIEEINEKVKAEFIRN
                     NVRLG"
     gene            22561..24006
                     /locus_tag="PC494_002018"
     CDS             22561..24006
                     /locus_tag="PC494_002018"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HDF3912519.1"
                     /translation="MAKNEKQFVEEITKMEDDFPQWYTDVITKTDLVDYAPVKGFMVV
                     KPYGYALWEKMQEFMDKKFKETGHKNCYFPLLIPESLLNKEAEHVEGFAPEVAWVTHG
                     GNKKLEERLCVRPTSETIICTMYAKWLKSYRELPYLYNQWCSVVRWEKSTRPFLRTSE
                     FLWQEGHTLHETAEEAQEETIQQLEVYKALCEELLAMPVVAGQKSESEKFAGGERTYT
                     IEAMMHDGKALQSGTSHFLGQHFTKAFDITFADREGNLANPYHTSWGASTRLIGGLIM
                     THSDNRGLVLPPRVAPIQVVIVPIAAKKGNVMETVDKIYADLKAKGVAVEVDDRDNYT
                     TGWKFNEWEMKGVPVRVEIGPKDIENNQAMVFRRDTLEKDSMPLEGLADAICDLFDVI
                     HNDMFEKARKHREDNTSIVENMDEFRKALEEKPGFIKTMWCGDAECEAKIKEETGATI
                     RCLPFEQENLGHKCVYCGKEADSMVVMAKAY"
     gene            24445..25926
                     /locus_tag="PC494_002019"
     CDS             24445..25926
                     /locus_tag="PC494_002019"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HDF3912520.1"
                     /translation="MNVRVRFAPSPTGFVHIGSLRTALYNYLFAKKMGGEYILRVEDT
                     DQSRLVEGAIENMLNAMKWAGVNHSEGVILDDSGKVVQKGEYGPYIQSQRLDIYQEYI
                     KQLLDSGKAYYCFCTKERLDEVRDAQRAAGETAKYDGHCKNLSKEEVEANIKAGIPYV
                     IRLRLPENHTIKFTDLVRGDMEFNTNDLDDQVLMKTDGFPTYHFAVVVDDYLMKITHV
                     IRGEEWVSSTPKHVYLYEAFGWEAPVFVHLPNILNKEKKKLSKRQGDVAVEDFKKKGY
                     LPEGLVNYVALVGWSPEDNQELFTMEELEKAFSVERVSKSGGVFDTEKLNWVNQHYIK
                     DGDDAYLTDLAIPFLIEDGFITEEEATNKYDFLKSMISVLKEKLQYVKEVTEHASIFF
                     GDKIEVETEEGREFLRLEHIPTLIDALREKIEKTEVLNAEFVQAMLKEIQKEYKIKGK
                     NLFMGSRIILTGQMHGPDLPKVMEVLGKETCLNRIAYVKNNIL"
     gene            26147..26302
                     /locus_tag="PC494_002020"
     CDS             26147..26302
                     /locus_tag="PC494_002020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3912521.1"
                     /translation="MYSNIDDVKKELKELCLEYVTILEKLKDEKMITEETFEKCSSQK
                     KIFLEEQ"
     gene            26450..27847
                     /locus_tag="PC494_002021"
     CDS             26450..27847
                     /locus_tag="PC494_002021"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HDF3912522.1"
                     /translation="MKVYNTLTRTKEEFVPLEEGKVKMYVCGPTVYNYIHIGNARPFI
                     IFDTLRRYLEYRGYDVTYVQNFTDVDDKIINRSHEEGISPEEVAAKYIKEYFVDCDGL
                     GIKRATVHPQVTDNIQQIIEFIKELEDKGYAYAVNGDVYFDTNKFEGYGKLSGQKQED
                     LEAGARIEVNDQKRHPMDFVLWKAKKEGEPGWDSPWGEGRPGWHIECSVMSKRYLGET
                     IDIHAGGQDLTFPHHENEIAQSEARSGKTFSKYWMHNGYININDEKMSKSKGNFFTVR
                     DISKLYDLEIVRFFMLSAHYRNPVNFSDEMLNQAKAGLERLYNTKEKLEFTLSNLVES
                     PLTEKEVELVKELDDFRQKFIDAMDDDVNTADAVSVIFELAKLINSNVDENSSLEFAK
                     KCLDEFNELTGVLNIVNKKKDTVLDKDIEELIQKRTDAKKNKEFQLADDIRQQLLDMG
                     IVLEDTRQGVKWKRI"
     gene            27832..28245
                     /locus_tag="PC494_002022"
     CDS             27832..28245
                     /locus_tag="PC494_002022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HDF3912523.1"
                     /translation="MEKDIKMEKTELVTMSPLVLAYLGDTVYETYIREYLIRQNTQRK
                     VNDLHKLAIKYVKAKAQATIIHEIEIELTEEESKIYKRGRNQKSNTSPKNADIIDYKH
                     ATGFEALVGYLYLNNEIERLQYIINKGIKIIERDM"
     gene            28351..29109
                     /locus_tag="PC494_002023"
     CDS             28351..29109
                     /locus_tag="PC494_002023"
                     /EC_number="2.1.1.148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent thymidylate synthase"
                     /protein_id="HDF3912524.1"
                     /translation="MKVKLISHTPEPEKVIAMAAKLCYSPVGTDEIEKDLTDESIEKF
                     LNMLLSIGHGSILEHASFTFSIEGISRACSHQIVRHRIASFSQQSQRYVKLEQFEYII
                     PPEIEKIEKAKELFIDSMKKDQENYDKLVEILFENHYNDLIKNGKNEKTAKRQAEKKA
                     IEDARYVFPNACETKMVFTINARSLFNFFEHRCCERAQWEIRNLAVEMLREVKKVAPI
                     LFKKTGPSCVNGSCPEGTMTCGDIVQVREKFKAL"
     gene            29122..29859
                     /gene="rlmB"
                     /locus_tag="PC494_002024"
     CDS             29122..29859
                     /gene="rlmB"
                     /locus_tag="PC494_002024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HDF3912525.1"
                     /translation="MASIEGRNPVIEAIKSDREIDKILIANSAKEGSIKKIIGMAKDK
                     NIIIQYVDKHKLDEVSTSHSHQGVIAYASEYKYYELDELIDLAKNKDEDPFFIILDEI
                     TDPHNLGSIIRTADAVGAHGVIIPKRRSVHITPVVAKASAGAVEYMPVCKVTNIVNTI
                     KRLKEEGLWIAAADMDGETFYKQNLTGPLGVVIGSEGFGISRLVKQNCDFIVKMPMIG
                     NVTSLNASVAGGILLYEIFRQRLDKSK"
     gene            29862..30389
                     /locus_tag="PC494_002025"
     CDS             29862..30389
                     /locus_tag="PC494_002025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NYN domain-containing protein"
                     /protein_id="HDF3912526.1"
                     /translation="MKKNINHYLIIDGYNIINAWDNLKELAKEDLEDSREKLIDDIIE
                     FSEFMGYKTIIVFDAYNVKNSREKVEKRKHITIVYTREHQTADSYIEKFITSLSKYDD
                     VKVATNDYAEQQMILGKGATRMSARELKLELDRSKNKMKEKNIGLRKKIQRNWLEERL
                     DKETLSKLENIRRKR"
     gene            30454..31101
                     /gene="sigH"
                     /locus_tag="PC494_002026"
     CDS             30454..31101
                     /gene="sigH"
                     /locus_tag="PC494_002026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sporulation sigma factor SigH"
                     /protein_id="HDF3912527.1"
                     /translation="MLVAKEKSYELVDNCQQDEYNIVLRASEGDKIALEYIITKYRNF
                     VKAKAKSYFLIGADKEDIIQEGMIGLYKAVRDFDGSKTNSFKCFAEICITRQIITAIK
                     TATRQKHIPLNSYVSLNKPIYDEESDRTLLDIIATSIVTDPEELIISKEELKNIESKM
                     NELLSDLELEVLELYLNGKSYQFIADKLKRDVKSIDNALQRVKRKLEKHLENRND"
     gene            31175..>31707
                     /locus_tag="PC494_002027"
     CDS             31175..>31707
                     /locus_tag="PC494_002027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HDF3912528.1"
                     /translation="MAKAKYERTKPHVNIGTIGHVDHGKTTLTAAITKTLYDRYQLGE
                     AVDFANIDKAPEERERGITISTAHVEYETPNRHYAHVDCPGHADYVKNMITGAAQMDG
                     AILVCSATDGPMPQTREHILLSRQVGVPYIVVFLNKCDMVDDEELLELVEMEVRDLLT
                     EYDFPGDDTPIVRGSAL"
BASE COUNT        12926 a         3325 c         6057 g         9399 t
ORIGIN      
        1 tagataataa acatacttaa gaaaacagat aaaatcaaat ataataactg tatattaaaa
       61 taacttaaaa aaattatttt attataagtg caaaatatac ctatttaaat aagataagag
      121 gggaggattt tatgtgtata taaaaggtgt aaatttagga ggttggttag ttttagaaaa
      181 atggatgacc tcaagtttat ttgaaggcac agaagctgaa gatgaatact atttaccaag
      241 acagctttca agagaggcat atgaatctag aattaagact catcgtagtg aatacatcac
      301 agagagagat tttgcaacga ttaaatctat gggatttaat tcagttcgta taccagtacc
      361 atactttatt tttggagatt gtgaaccatt cataggatgt gttaaagaac ttgataaagc
      421 atttgcttgg gcagataagt atgggcttag tatattgata gacttacata cagttccagg
      481 aagccaaaat ggatttgata atggaggaat atcaggtata tgtagctggt cacaaaatcc
      541 agaatatgta gcgtttacat taaatgtatt agaaagactt gcaaaacgtt atgggatgag
      601 gcatgaattg tatggaatcc aaattttaaa tgagcctata acagaaagaa tgtggaacat
      661 aatgaatgtt ccaaatcggt ttaaggctgt agataaggag atggcaaggg ggagtaaacc
      721 taattcatta gagtttttac gtgattttta tataaaagca tataaggtaa tgcgtcctta
      781 tatgagagag gaaaacgtta tagtatttca tgatgcattt gaattaaaag catggaaaga
      841 ctttatgaga gaggaagaat ttaaaaatgt tgttctagat acacaccaat atttgatgtt
      901 agctgaagca gatggatgtg aacaaagtat tgatagctat ctcaaatata ttagagaaaa
      961 ttatgctaaa gatattttac aaatgcaaaa atattttcct gttatatgtg gggagtggag
     1021 cttatttaat tcatatgctt gtggtataga tacaaatgga ggtcaatcac ctctaaatgg
     1081 gattgaatca aatatagata aattatcaaa agacgataaa agagaattat ataggaagat
     1141 agcaaaagca cagcttgatg catggagaaa tggaagtggt cactactatt ggaattataa
     1201 gttattacta gatacagtta atgaagaagg ttggatagga tgggatagtt gggacctagg
     1261 caaatgtgta gctcaagaat ggtatcctat agaatattaa actaaaattg gaggaaaaga
     1321 tatgattaaa aaccctatac ttccaggttt taatccagat ccttgtattt gtagaaaggg
     1381 agatgattat tatcttgtag tttcatcttt tgaatggttt ccaggtatac ctgtttatca
     1441 ctctaaagac ttaaaaaatt gggagttata tactcatatt ttgacagatg aaacaaaaat
     1501 agatttgaag aagcttcctt catctaaagg aatttgggca ccttgtttga cttattgtga
     1561 agaagaagat ttattttaca tagtttatgg aattatgaac tctatgaatg caagatattt
     1621 tgatgttgat aattatttaa ttacatcaaa agatataaag ggagagtgga gtgaaccagt
     1681 atatctacac tcatcaggtt ttgatgcgtc tatttttcat gatgatgatg gtaaaaagtg
     1741 gattgcatca ttagactggg agactagaga aggatatgaa aaacctggtg ttatatgttt
     1801 agtggaatac tgtacaaaaa agaaagaaat agtaggatat ccaaagagaa tatggtcagg
     1861 gggaactgat agaggttgta ttgaagcacc acatataaca aagcgtggag attactatta
     1921 tataatgtgt gcagaaggtg gaactggata tggtcatagt gtaactatgg gaagggctaa
     1981 aaatatatgg ggaccttatg aaaaagattc aatgaatcca attgtaactt caattccagg
     2041 cgatttttat gaaagacatg accctgacca tctaaagcct aaatactata atccagaatc
     2101 aaaacttcaa aaatctggtc atggaagcta tatagaaaca acatcaggtg aagtatattt
     2161 agttcatcta acatctagac catttgtacc agagttaagg tgtactttag gtagagaaac
     2221 agctattcaa aaaatgaaat ggacaaagga taattggctt cgaatggaag atgaaagtaa
     2281 tttggcaaaa gaatacgtat cagaaagtaa actagaagaa catttagttt catctatacc
     2341 aagttttgat gactttgatt caaatgaatt aggtttacag tactatgctc ctaggatttc
     2401 accattatca tttgcagatg ttaagtctag accaggatat gtaaggatta gaggacaaga
     2461 atcaagaaca tcattaaata aagtgagcat attggcaaga aaattaactt cagtatatgc
     2521 aagaataacc actaagatgg agttttaccc agaggtacat cagcatagtg cgggtttgat
     2581 aatgtattat gataatatga attatataaa tttaagaaag tattatagtg aaacattggg
     2641 tcaaagtgca ctatcaataa tacatcttga aaatggagag aaaacggaat ttttaaatac
     2701 taggatacca ataaaagata taccaatata tcttcgtctg tatatacaag gtcgtaagtc
     2761 atattttgaa tggagttatg atgaaaaaaa ctaccagaga ataggaaagg tatttgatac
     2821 aactaagttt tcagatgagt actgtaaata tggagaattt acaggtacgt ttataggatt
     2881 aacttgtgca gatcgtgtaa agcataaaca ctatgctgat tttgattttt ttgaatatat
     2941 agtagatgaa tcaaaagatg tcgattaata aaatcattac taaaattttc agagcaaagg
     3001 taaatcttat gctctgaaat aagaaacatt agaaggcaaa tcttacaaaa aggagtatgg
     3061 tattatgaat acagaagtta atgttaaagc aactacgatt aaatatgaaa agatttcatt
     3121 ttttgaaaga atttcttatg gttgtgggga tttggggtgc aatatcatat actcagctat
     3181 gtcagcattt ttgctgtttt attatactaa ttatgcagat gttagtgcag cagctgtagg
     3241 tagtattatg cttgtatcta ggatactgga tgggtttagt gacttaacaa tgggaattat
     3301 agtggataga actaaatcca aatacggtaa ggctaggcct tggattttga gaatggcgat
     3361 tccttttgct atagcagcag tattattatt ttctgttcca tcaaatcttg gtatcacttc
     3421 taaattaatt tatattttta ttacatataa cttagtttct actgttattt atacagcaat
     3481 caatgtaccc tatgcaactc taaattcact tataactcaa aaccagtatg aaagaggagt
     3541 attaagtata tttagaatga tattagccac ttgtggtacc ttactaataa atggacttac
     3601 actacctcta gttgaatact ttggaaataa tttatcagca tggactaaaa cattctttgt
     3661 atttggaata gcatctataa tggtattttt tataacattt actggaacca aggaaagagt
     3721 aaaagcagtt aagcaagata ggaatgaagt aataccattt aaaataggta ttaaatcttt
     3781 atttagaaat aagtactgga tacaaataac attatgttta gtttgtatat ttattgtatt
     3841 tgcgataaat ggtggttcat ccgtatatta tgcaaagttt attttgggag atgaaaaatt
     3901 atttggtcct ataaatatgg tttcaaatat atcccaaatt atagctatgt ttatggttgc
     3961 tccttttata aaaaaatttg gaaaaagaaa tgtattaata gtaggttcaa taatattaat
     4021 atcgtcaaat gttatgttta taatagttgg acaaaatcat ataggagtaa tatttgcaag
     4081 tgctataaag ggaataggaa gtgctggaat agcatcaaca atgtttgcta ttgtttcaga
     4141 tactattgaa tatggagaat ggaagactgg atatagaact gaggggctta taaatagtgc
     4201 atctagtttt gggtttaaag tgggaaatgg attaggttca gcaatattag gtgcagtatt
     4261 atcaattggt ggttatgtag gaacatcagc tactcaaagt gatttagcta tagtatcaat
     4321 aaaagtatgt tttatatacc tacctatatt tataacaata ttacaaatta tcataatgtc
     4381 tttttataag cttgataaag aatatagtac tatacttaat gaattaaata ctaaataatg
     4441 aaaaagtttc ttataaagtc ttaagtttaa ttaaggtcta ttgtaaatgt tccctataaa
     4501 aactattata tatttatgat tattgaagaa tttttagaga agcgaataat aaaaatataa
     4561 gaagacttta aatgatgaaa tggttggttt tttagaaatg atttaataag ttattgttat
     4621 ttaaagcatt ataagtggac aattaaattt taatttatgg agatgatatt taacaattag
     4681 aagtaatata taatatgcac taagaagcaa tttttcaact atttatgaag gtggtggtac
     4741 aagaaaagta tcaccttttt tttgttatac aaaaaaacag ttgacttttt atatgaaccc
     4801 cttctataat gttactgaaa ttaagtaaaa tgattgaaca aatgtaaaga taattgaaaa
     4861 gcttgatttt ggaggaaagc aaatgaaaaa aattggagac ttaagattaa tgatgaagtg
     4921 ttgttcactt tattacgaag ataatttgaa tcaacaggaa atagcaaatc aattgggaat
     4981 atcaagacca acaatatcaa gaatattaaa agaagctttt gaacaaggaa tagtaaaaat
     5041 acagatagtt gatgttttga aaaatgatta ccaaaaaata gagagaagtt tggagagaaa
     5101 atataaatta aaagaagtaa tagtagtaga tgataaacag gatgcactaa cacaaaaaca
     5161 agaactagca agagctgtat ctgaatattt aactagagta gtaaaggaaa atgatataat
     5221 aggtgtttca ataggaacaa cactaaaaga aataccaaga tatgtggaaa aaagtaactg
     5281 taaaaatgtt acatttatac ctctattagg agggattgga gacaatgaaa tagatattca
     5341 tgcaaatcaa atagcagtaa gtttagcgag ggcttttgga ggtgatttta aattattaca
     5401 tgctccagct gttatgtctg acttgtctac aaaagagaaa ctttgcaaag acgaaaaaat
     5461 taaagaagta ctagatttaa tagataaaac aactatagca attgtgggta taggaaatcc
     5521 tatgagttta aactcaacaa taatggcttc tggatacatg aatgaagcag atatagaaga
     5581 tttaaaaaaa tacaactcaa taggtgcaat ttgtttacaa gcctttgata aagaaggaaa
     5641 aacttctata cttgaattta atcaaagagt attaggagtg aaactggaag atttaaaaaa
     5701 gataaaaaga acaataggtg tcgcttcagg agatgaaaaa atagaggcaa taaaggcatc
     5761 attaaaagcg aaatttataa atagtttagc aattaatcac agtttagcac ttaaattatt
     5821 agaagattgt gactaataga aagatagata aaagttaaca ggagggaatg tatatgtcaa
     5881 tatcaaaaga aacattgctt gaaatgtata agagaatgaa tcaggctaga aaatttgaag
     5941 agaaagttag ttggtttttt gcaagaggta tggttcatgg aacaactcac ttatctgtag
     6001 gtcaagaagc gtcaagtgtg gcggctgtaa tggctttaga aaaaggagat ttagtatcat
     6061 taactcatag aggacatagt caatttatag gaatgggaat agacctaaat aaaatgatgg
     6121 ctgaacttat gggtaaagaa actggatttt gtaagggaaa aggaggctca atgcatatag
     6181 cagatattga gtcaggtaac ttaggagcaa atggagttgt aggtggaggt cttacaatag
     6241 ctccaggagc tgcacttaca caacagtata aaaaaacagg caaaatagtt ttatgtagtt
     6301 ttggtgatgg agcatcaaat gaaggtactt ttcatgaagg aataaattta tcttcaatat
     6361 ggaaattgcc aataatattt tactgtgaga ataatttata cggtatgtca acaagcataa
     6421 aacgtcatat gaatatagaa agtattgcca ctagagcagc ttcttatgga atagaaggaa
     6481 tatcaataga tggatataac ccaatagaag tatacgaaac agtacaaaaa gctgctgaga
     6541 agtgtagaag aggagaagga cctgtattaa ttgaaagtag aacttataga tggttaggtc
     6601 attcaaaatc agatgcaaat gtatatagaa caaaagaaga aatagaatca tggaaagcaa
     6661 aagaccctat tgaattttta aaaaattatc ttatagaaaa taatctatct aatgaagatg
     6721 aattagataa gattcaagaa tttgcaaagc aatcaataga agatgcagta gagtttgctc
     6781 aaaatagccc aaatccaaaa atagagtctt tattagagga tgtatatgca gactaagaat
     6841 ggtaaaggag gaaaataaaa atgagtacaa gggaattaac atatgcacaa gcaataaagg
     6901 aagcaatgtc agaagaaatg agaagagatg aaaatgtaat atttatggga gaagatatag
     6961 gaatatatgg aggagcattt ggtgtatcag ttggtatgat agatgaattt ggaccagaaa
     7021 gagtaaggga tactcctata tcagaagcag ctatagcagg agcggcagca ggtgcagcag
     7081 caactggctt aagacctatt atggaagtaa tgtttatgga ctttgtaaca atttctatgg
     7141 atgcaattgt aaatcaagcg gcaaaaatga gatatatgtt tggaggaaaa gcacaagttc
     7201 caatggttgt tagatgtcca ggaggttctg gaactggttc agcagagcaa cattcacaaa
     7261 gtttagaagc ttggttttgt catgtaccag gagtaaaagt agttgcacct tctacaccag
     7321 cagatgctaa gggattgttg aaagcagcta taagagataa taatccagtc atatttgttg
     7381 agaataaatt gttatacaga aaaaaaggtt ttgtgccaga agatgattat gtaattgaaa
     7441 ttggaaaggc agatattaaa agagagggta ctgatgttac agtaattact tatggaagaa
     7501 tgttacaaag tgttaaagaa gcagcagaga ctctatcaaa agaaaatata aatgttgaaa
     7561 ttatagattt aagaacttta tatccattag ataaagagac tatagtaaag agtgtatgta
     7621 aaactgggag agttttaatt tgccatgaag cagctaagac tggtgggcta ggtggagaaa
     7681 tatcagccct gataacagaa agtgaatcat ttgattattt agatgctcca gtaaaaagaa
     7741 tttgtggaaa agatgtgcca ataccatata atccagagtt agaaaaagca gttgtcccaa
     7801 gagttgatga aatagaagaa gcaataaaat ctttaattgt tagataagga gggatagata
     7861 tggtggcaaa taaaataaaa gccacaccag cagctagaag tcaggcaaga aaagacaata
     7921 taaaattaga taggctgatt ggaagtggag aaaatggaag gattcattta gtagatgtgt
     7981 taaattattt aaaagataat aaagcaaata ctactccttt agctagaaga atagcagaag
     8041 atttaaatat agatttagaa actattgtag gtactggata taatggaaag ataagaaagt
     8101 gtgatgtgga aaaattaact gcaaaagaaa ctattgtatc aactaataca tctaaatcta
     8161 gtgagaaaaa agagctgaaa attgaaaatg aaaattcaag catgtttaac acagtagaag
     8221 gaatatttga aaagccaaat ccaatgagag ccactgtagc aaaacgaatg tcagaaagtt
     8281 attttagtgc tcctgtattt acattcaata tagaagtaga tgctacagaa ttgaaggtac
     8341 ttagagcaaa gttaatcgac acagtaaaag aatcaactgg agtaaaatta actatgacag
     8401 atttaatagt aatggcagta tctaaaatac ttccaaatca tcaagcctta aattcagcat
     8461 ggacagatga gggtatattt agatataaag atgtaaatat agctattgca gttggtttag
     8521 atgaaggctt atatgttccg gtagtaaaaa atgcaaacaa aaagtcttta aaagaaatag
     8581 caaaagaaag caaagaactt gcggaaaaag taaagacagg gaaacttatg ccagcagacc
     8641 aagaaggtaa tacatttaca ataagtaatg ttggaatgta tggtataact acatttacac
     8701 ctataataaa tatgccttca agtgcaatct taggggtagg tgctacacaa gataagtttg
     8761 ttccagtaaa tggagaggct aaaataaaac ctataatgaa cttatcatta acatcagacc
     8821 atagagtaat agatggaaca gtagctgcaa aattcttaaa agatttaaaa gaattgttag
     8881 aaaatccttt atcaatgctt gtataggttt tgatattttg ttactgatat aaatagtttg
     8941 aatagattat attattataa ttgtttcagt aaatttaaag cttttatata ttaagaatta
     9001 tttttaacag taactatatg tgaatatgat ttgcttaatt aaaatataag aaaataaata
     9061 ggaggagagc ctatgtcagt agaagtaata atgccaaaag caggagtagc catggaagaa
     9121 ggtactatag tatcttggct aaagcaagaa ggcgaagaag taaagattgg agaacctata
     9181 ctagaaataa caacagataa agttaatatg gagatagagt cagaaggaga aggtacactt
     9241 gctgtaatca tacataaaga ggaaggtgaa gtattaccag tatttacagt aataggtgta
     9301 atagcagaaa aaggggaaaa tcaagaggaa gtaaaagcta aatatttatc tggaaatgtt
     9361 tcaaaagaag atacagttaa agagaatcaa aatatagaag ttaaagaaga aaaaataaac
     9421 aaaaaagagt gtaatcatga ttatgatgta gtggtaatag gaggaggacc tgggggatat
     9481 ttatcagcat taaaagcagc tcttttaggt ggaagagttg ctttagttga agaaaatata
     9541 ctaggaggta cttgcttaaa tagaggttgt atccctacaa agacttatat aaaaacagca
     9601 gaaatattag aagaaattga ccaattatca aagagaggtg taaaagtaac tgtagataaa
     9661 gaacaggaca ttaagaaggc cataaaatat aaaaatagag tagttaaaaa acttacagct
     9721 ggtgttggcg gattattaaa aagtagagat gtagatgtgt ttaatcttaa agctagtgtt
     9781 aaagaagagc ataaagtaat tttatcagat ggaaaagttt tagatacaga aaatataata
     9841 attgctacag gttccaaagt aaggatatta cctataaaag gaatagaatc aaatttaata
     9901 ataactagta cagaagcatt agatttggaa acagtgccag aagaattagt aataattggt
     9961 ggtggagtga ttggttgtga atttgcagag atattcaatt caagaggttc taaagtaact
    10021 atagtagaaa tggaagatag agtaatccca agaatggata aagagttaag cgaatcttta
    10081 aaatattctc ttagtaaaaa aggtataaat gtattaacta aaaagaaagt ttctgaattt
    10141 aaagaagaag gaaataacat attagtgtgc attgaaggtg aagagccaat aaaagcagat
    10201 ttatgtctat atgctatagg aagagaagct aatctttctg gcatagagga cttagatatt
    10261 aaaatagata aaggttcaat agttgtaaat agtaaaatgg aaacaagtat gccaagcata
    10321 tatgcagtag gtgatgttac tggaggtgta atgttagctc atgctgcttt taaaatggga
    10381 gaggtagcag cttcaaatgc tctaggtgtg aataaagaag ttgacttagg tgcattacct
    10441 agttgtgttt atacaattcc agaagtagca gcagttggta ttacagaaga ggatgctaga
    10501 aaaaaatata atgtaaaagt tggtaagttt aattttgctg gaaatggaag agctttagct
    10561 tctggtcaag aacaaggata tgtgaaggta gtagcagatg ctaaatatgg agaaatttta
    10621 ggtatacata tgtttggatg tggtgtagca gaacttataa atcatgcagc atcatttaaa
    10681 gcgttagaga tacctactga tgaagcaagt gagttgatat ttggtcatcc atgtacttca
    10741 gaagctttaa tggaagcttt ggcagatgta aatggagaat gtttacactt acctaaaaaa
    10801 taaatctaaa cataaattat taatttaagt ctattattaa tattaattta tatcataaaa
    10861 ttttaaaaca cttacttagc catacccctt attatgcaaa taatttattt gcataataag
    10921 gggtattttt tatggaaaaa tatagaatat agaatccttg tagtttttgt tgtacaaaaa
    10981 agatagtaat ataaaataac attatcattt tagaatgatt tcaattgtaa ttaggaaaag
    11041 tgattttttt gtttttaaaa aaagtattat ttgtaaaata taaaaaaaaa tttcttaata
    11101 tttgaataaa agaatagctt aatttaaatg ttattacttt ataaaaaaat aataagtaca
    11161 aaaaaaacaa tatatggcat ataagttgct atataaataa taaggaggga acaattataa
    11221 atgaggcaaa gaataaaaaa cttaattgaa aatgaagata agaaaaatcc tttaacagat
    11281 gaagtgattt caagtaggtt aaatattcga agagaagatg ttaccttttt gagaaatgag
    11341 ttaaaaatag aagattcaag acaaagaaga aaagttgttt taattaaagc tataaaagat
    11401 attttaaaag aagaaaaaac tataaataaa aatgatataa caagaagatt aaacagcatt
    11461 gggtttacag tatcaagatt tacagtcata caatacttaa aagagattca agattctggt
    11521 gacctaaaac ttgataaaga gagtgatgat aaaaaagaag aaataatcaa taatagagaa
    11581 aataaagata tagcatttga taaactcata ggtagtagtg gtagcttaag tacaattata
    11641 aaactagcca aagcagcaat tctttatcca cctcatggtc ttcatactat tattatgggg
    11701 ccaactggtg ttggaaagag tgagttagca gagtgtatgt ataaatttgc agtagaatca
    11761 tccagattcc ctaagaatgc accatttata gtttttaatg cagcagatta ttcagagaat
    11821 ccacagcttt tgctatcaca gttatttgga cacgttaaag gtgcttttac aggagctgat
    11881 gagaacaaag aaggattagt atcaaaggca gatggaggaa tattgtttat agatgaaata
    11941 catagattac ctcatgaagg tcaagaaata ctatttcaac tgattgataa aggtatggtc
    12001 agaaagttag gagaaacaag actaacacat aaaatagatg taatgattat ttcagcaact
    12061 tctgagccaa tagattctca tttacttaat acatttaaaa gacgtatacc tgtaacaatt
    12121 gaaataccag aattagttgc aagaccatta aatgagaggt ttgacattat aaataatttc
    12181 ttcttaatag aagctcaaag aatgggagca aacatacata taaagtcaga tgtattaaaa
    12241 gctcttatgc tttacgattg tataggtaat gtaggtcaac ttagaagtga tattcaagta
    12301 gcttgtgcta ggggactatt aaaccaactt acaaacaaac taaaagaagt aaatataagc
    12361 atatcagatg tacctggata tgtaaaacaa ggtcttataa aaatcagaaa ttgtagaggc
    12421 aaaatagaaa attatgtaga tggggattta attatagatt caaatcttca aggtgagata
    12481 gaaaagaaaa atgaagatat atatactttt ccagatgaaa tatacaaact tactgaaaga
    12541 agacatattg atttattgga acaaggttta gattttgatg ttataaatag aatcattgga
    12601 ggagaattag aaagttgcat tcaaaaatac ataaaacaag ttaaaaaagt ttctattagt
    12661 aacaatcttc cagatataag tccaattgtt ggaaaatata tcgtagagct aacttatgaa
    12721 gtaatcaaaa tagcatcaca atacctaagt tcactagaac caaatctaca tttatgttta
    12781 gcagttcacc taaaagcagc ttttgagaga ttaaaagaag gaaaagtaat atcaaatgct
    12841 catttgaaag aaataatagg aaattatcca gtagaatatt ctgtagcaga aaaggtagct
    12901 caatatttaa aggaaagata taacataaac ttaccaaaag aagaaatagg tataatagca
    12961 atatatttta aaatgagtag tagaagagat atgtctgaac aaaaaaagat aggcgtactt
    13021 cttatggctc acggaagagt agcatcttct gtatgtgagg ttacaaataa actattagga
    13081 attaatcacg caaggtattt agatatgcca tttgagaaga agccggaaga aatgattgaa
    13141 gaagctacta caataataaa agatattgat gaaggtagag gtgtgattat attagtagat
    13201 atgggttcac tttcatattt tggagatatt atttctggaa agactggaat taatataagg
    13261 acaatatcta gatttgatac attgctttct atagaggtta tacgaagagc agttttacca
    13321 gatttaacaa tagacgagat agttgatgaa gttaaaggta tagagccaca agtaaaagaa
    13381 aaggttagta aatgtaacaa tacaaaagta gattttagaa aacctataat tttaacatta
    13441 tgtattactg gattaggggg agcttgtaag ataaaaaaaa tcttagagga aaatattaaa
    13501 agtataactg aaaaggttga tatagaacct ataggtatga ttgaatatcc aagtcttgat
    13561 ttagagataa aacaaataag caatgataaa aatgtaatcg ccatagttgg aacaattgac
    13621 cctcagatag caaatatccc tttttttagt ctagtagaca taaatgataa agcaaagtta
    13681 aatcaaataa ataacctaat tgatacaaat caaattggtg aaacaaataa aaaatatgaa
    13741 ttatcagatt taatacataa agaagatata tttgtggatt tacaggttaa atcaaaagaa
    13801 gaagttctaa aatatatgag taaaaaactt agagagaaag gttatgtgac aaaaaatttc
    13861 tataaaaaag tagtggaaag agataactta tttccaactg aattatcaga tgaaatagca
    13921 atacctcaca cagatggaat agatgtaatt aggccagcta taagtatagc catcttaaag
    13981 aagcctattg tgtggagtaa aagtaaagta aaaataatac ttttattagc tgtagaccaa
    14041 aagtgtttta atccattaag cactctactc tcatttatag aaacagatga atttaagaag
    14101 ataaaaaaca ttaaagatag agattttatt agggagatga tattagatgg agtcaatgaa
    14161 aataattagt agcaatttaa tttttaaaaa tattgaagtg tctaacaatg aagatgcatt
    14221 aaagtttttg ggacaacgtt tgtttgacga acagtatgta aaagaaagct acatacaagc
    14281 tgttgtagca agagaaaaaa agtatgctac agggttacca acagaaatat acggagtggc
    14341 aataccacat acagatatag tacatgtaaa tgagccagga atagcaattg gaatactgaa
    14401 taaacctgta aaatttataa tgatgggtac agacgatact gaaattgatg taaaagttgt
    14461 atttatgtta gcagtgaaag agccacaaga acaattgcaa ctattagaaa aacttatgac
    14521 tatatttcaa gataagaata tactaaataa tattgttgac ttaagtgaag aaagtgtgag
    14581 tgatttatta aactctaaat tgaaaaatta aacatgtaaa gtatattaaa aatgtaaaat
    14641 taaacatgca aagtatgtta aaaaatataa aaagattatt aaagatttct aactatagat
    14701 atctttaaaa taaaataatt tcaatggggg tgactaatgt ggctaaaaag atattagttg
    14761 catgtggaac aggagtatgt acttcaacaa ttgctataaa caaattaaag aaagcacttc
    14821 aagacattgg taaattggat atggttaata ttacacaatg taaagtagta gaagttgcat
    14881 caaaagcacc tgattatgat ttaataattt gtactacaca agtatctagt agtataaaaa
    14941 caccagtgat aaatggatta ccttttttaa ctggtgtcgg aatggataaa ttaatcaatg
    15001 atgtattaga agagttagaa ttataattaa aaaaattaag gaacatggtc tctaaaatca
    15061 taagttttag agacttaaaa ttaaataatg gagggtcttt atatggagat attaaatttc
    15121 attgttggtc taggtgcaca agtaatgatg ccaataataa tatgtatttt tggtttgata
    15181 ttaggtacaa aactaggaaa atctttaaga gctggtttaa ctgtgggagt tgggtttata
    15241 ggtcttaata ctattatagc tttgctaaca gataatttag gtccagctac acaacaaatg
    15301 gttaagaatt tagggctaag tttatcaata atagatgtag gatggccagc agcatcagct
    15361 atagcttttg catcaacagt aggggcttta attattccaa taggtcttgt ggtaaatata
    15421 gttatgctaa ttactaatac tactcaaact gttgatgtag acatatggga ttactggcat
    15481 tttgctttta caggagcttt agtggcaggg gctactcaaa gtgtaatgtg gggagtattt
    15541 gcagcagtag caaatatggt aattgtattg gtaatggcag atttaactgc tccaggtata
    15601 gaggaatatt taggtatgcc aggtatatct cttcctcatg gatttacaca ggcctttgtt
    15661 ccaattgcta tagtagtaaa taaattatta gatctaatac caggtataaa taagattgag
    15721 ataaatgctg atacattgca gaaaaaattt ggattatttg gagaaccttt aataatgggg
    15781 tctgtaatag gtgtaataat tggtattgct gcgaaatatg atataaaagg aatattacaa
    15841 ttaggtgtaa ctatgggagc tgtattaata ttaattccaa agatggcagc attattaatg
    15901 gaaggattat taccagtatc agaagctgca caggaattta ttgagaagag atttaaaaac
    15961 agaggcaaga tttatatagg cttagattca gcagtaggaa taggtcatcc tgttacatta
    16021 tcagttgcac tagtgttggt tcctttgact atacttatag cagctatatt gccaggaaat
    16081 aaagttttac catttgcaga tttagcagta attccatttg cacttgtatt aatcgtacca
    16141 attacaaagg gaaatgtgtt tagaacatta ataataggaa taattataat tacttctgga
    16201 ttattaatcg caactaactt agctccatta tttacccaaa tggctttaaa tgctagtttt
    16261 aaaatgcctg aaggagcaac tatgatttca agtatttgtg atggtgcgaa tccattaagt
    16321 tgggtatttg taaaagttat gaactataaa gttattggag gagtagtttt tggagttata
    16381 gctttaggaa tggctattta caataggaat agaataataa atgaaaataa aaagctatct
    16441 atagaagaat aaggttaaaa caattttatt aaggagtgta taggttatga aaaaatataa
    16501 atatgattct aaaagatact tactcagtgt tacaatacca ggatttttta tgattttaat
    16561 attgatttat gcactgttta ataactatac aaattttaat ttgaatatat atagtttgtt
    16621 aataattgtc tgtacttata gtatattcaa tacttttata tcatcaagta atcctaaaaa
    16681 aattattatt gatagcaaat gtatacattt tacctcattt atgactacac ataagtatga
    16741 acttaaagat atagaaaaga taagaataag agaattttat aataaaaaaa tttatctaaa
    16801 aattaatgat ggaaaccttt ttaaaggtag gtattggata agaacaaata tgtttaataa
    16861 tagtatagca ttatatagct atttcattga gttggaagag tgcttatatc cagattcact
    16921 aaaatttaga aataaaaaat ttgagaataa gaacatataa aaataaaaaa ttgaattgaa
    16981 gcctagctta atcttttttg ataatatata agtttgaact ttatactaaa tttttagaat
    17041 tttcaatcaa gataataaca taatagctaa gcaattagaa cacaattaag atgtataagg
    17101 catgtatatg atgaatggga ggatttaatt aatgttatta gagaaattaa gaaaagaagt
    17161 attacaagca tctttagacc ttttaaacta taatttagtg acattaacag gaggaaatgt
    17221 aagtgggaga gatgaacaaa ctggctatat agcaatcacc ccaagtggaa tggattatag
    17281 aaatcttaca ccaagtgata ttgttatagt agatgtagat ggaaatatta tagatggaaa
    17341 atggaaagca tcagtggatt tatcagacca cttgtatata tataagcata gagaagacat
    17401 aaatagtata attcatacac attctacata ctcaagttgt tttgctattt taaatgaacc
    17461 tatagaatgc gcaagtacaa ctcttgcaaa tgaagtaggg ggttcagtac cagttgcaaa
    17521 attttcacca ccaacatcta aaaagatggg aaaatgtgtt attgaagcaa ttggtgacaa
    17581 aagagcatgt cttttagcaa atcatggcgt aattgcagtt ggtccatctg taggacatgc
    17641 tcttacagcc gctgtaatgt tagaagattc agcaaaagta tattacttag caaaatcaat
    17701 tggcacacca gtgctactgc ctgatgaaga aattcaaaga gcgagagatg tattttttaa
    17761 tgtctatggt caggataaat aaattagata aaattttaaa agtaatatga aaatatagat
    17821 attcaatgat attaaggaga tttataatga tataataagt ttaatagtta agaagtaaaa
    17881 tatgaaatgt aatagtatat aaattcattt aagactaaaa agaataagat aaaataaaaa
    17941 ggagtctgta tttctatgta ttacttatta aacaaaagca caaatcctta ctttaatttg
    18001 gcattagaag aatatctatt tttaaatgat aaatataatg atgatattat aatcatatgg
    18061 agaaatgaag aatccatttt tataggtaaa aatcaaaatc catatcagga agtatatcat
    18121 gatgttattg aaaagggaga aattcctatt ttaagaagaa tatctggagg aggaactgtt
    18181 tatcatgact taggtaatat caatatgtca ttcatacaaa aagataggca acttcatgag
    18241 atagattttt tggagcatac taagtttatg caaaagatgc tttcaacctt aggactagat
    18301 gtatctataa ctgaaagaaa agatttattt ttaaatggga aaaaaatttc aggttctgca
    18361 cagtctataa aaagaaaaaa ttctctttat catggaactc ttctttacga ttcagattta
    18421 aataaattaa ctaaatattt aaattcaaat aaagcaactg aatcaaatgc aactaaatct
    18481 gtttcaagta aagttacaaa tattaagttt ttactcgaaa aagatataaa ttacttttta
    18541 gattattgtg ttgaatattt aaaatctaat ataaagaata taaaagaact tgaattggat
    18601 gaagaagata ttaaaagtgt atacaatata ggagaagata aatataaaaa gatagagtgg
    18661 acatatggta aaacgccgaa atttcaagta gtgctaccat ttaataatga aagtaaaata
    18721 aatatacatg ttaacagatg gaaagtatca aaatttttta tttcttatga tgataatgta
    18781 attaatatgg acaagttgtt agatttgaat ttctttaaag aagaaataaa agagagtatt
    18841 ttagaaaatt atccacatta catagattta atcaatttaa tattttaata taaaacctct
    18901 aatttgataa aattgtctta tatcaaacta gaggttttta atattcttgc atattaacaa
    18961 ccattacaaa attgtaaaat taaaaacaac actattgaaa aatcaatata tatttgttta
    19021 aatatatgtg tttttcatta gcaaatagac attaactatt tatacaactg aaaatttaat
    19081 atataattaa tcagatggtt aaaataaaaa tattaaaagt tttaataaat gatggttaaa
    19141 aataaaatac gaggtgatac catgtatagt gttataattg ttgcagcggg aagcggaagg
    19201 agaatgaact tagatataaa caaacagttc ataaaattaa gagaaaaaga aattattgct
    19261 catacaattc aagtttttta tgaaaatata aatatagatg aaatagtggt atgtataaaa
    19321 aaagaagaag aagatttttt taaagaaaat ataataaata agtataactt taaaaatata
    19381 aaaatagcat atggcggaaa agaaagacag gactcaatat ataatggttt aaaaaaatta
    19441 gataaaaatt gtgatatagt acttatccat gatggagcaa gaccatttgt cgaccataga
    19501 ataatcaacg aatctataaa ggtagctaaa gaaaaaaagg ctgtggttgt aggtgttcca
    19561 gtaagtgata ctataaagat agtgtcagat ggaacagtaa aagaaactcc agaaagaaat
    19621 ttgctgtggg cagcacaaac ccctcaaacc tttgaatata atctcataat agatgcttat
    19681 gaacaagcat ataagaacaa ttattatggt actgatgatt caatgttggt agaaaatata
    19741 ggtcaaagtg tcactatggt aatgggttct tatgaaaaca taaaaataac tagtccagaa
    19801 gatttaaata tagcagaaca aatattaaat atggaaaaaa gagatgaagt taacagtaga
    19861 aggagaatta tatgagaata ggattaggat atgatgtaca caaattaaca gaggatagaa
    19921 aacttataat cggtggtgta gagataccac acgataaagg tttgttgggt cattctgatg
    19981 ctgatgtatt gatacatgca ataatggatt ctattttagg tgctctagca ttaggagata
    20041 tagggaagca tttcccagat acagatgaag aatataaggg agcagatagt atgaaattat
    20101 tagaacatgt gtataatcta ataacaagta aaggatataa aattggtaat atagacagta
    20161 ctataattgc tcaaagccct aagatggctc catatattga gagtatgaga agtaatatat
    20221 caaaagtttt aaacacagac attgataata taaacataaa ggcaacaaca gaagaaggtc
    20281 ttggttttac aggagcaaaa cagggaatag cttcacaaag tatttgttta ttattgttga
    20341 caagtcagaa taattaatat attattagta ataagtttaa tggatatcaa gtaataggcc
    20401 tatatagaat atctataatg tatgaattta agtgaaatta atataaatat aaaattagct
    20461 atgataaaga aatagtaaaa tgatgaaatc ttcacagaga gaaaacggtg gtgagagttt
    20521 tcaagaggaa gtctttgaac ctgtctttta gcttaaaggt ataaaaatct ttacggtagg
    20581 aaccgttata ttcccaaaag agagctattc atatagctaa ctagagtggt accgcggaaa
    20641 ttaaaccttt cgtctctata cttgtataga gatgagaggt tttttatatt ttcaggaagt
    20701 taatattcag gaggaatcta ttaatgaaaa tgtcaaaaat gtttatgccg acattaaaag
    20761 aaatcccagc agatgctgag attacaagcc atcaattaat ggttaggtca ggcatgataa
    20821 aaaaaatgac ttcaggtgtt tataaccaat taccaatggg gttaagagtg ttcaaaaaaa
    20881 ttgaacaaat aattagagaa gaattaaata aaaaagattg tcaagaaata ctttgtgcag
    20941 ccttacttcc ttctgaatta tggaaagagt ctggaaggtg gactgctatg ggtgaagaaa
    21001 tgtttagact aaaagacaga acagaaagag agtactgtct tgggccaaca catgaagaag
    21061 cattcactga tataataaga caagaaatta cttcatataa acaattgcca ctgaacttgt
    21121 accaaataca agtaaaatat agagacgaga gaaggccaag atttggtgtt atgagaacta
    21181 agacttttac aatgaaggat gcctatagtt ttgatgtaga tgataaaggt ttagataagt
    21241 catatcaaga tatgtttgat gcatatgtaa gtatatttaa tagatgtgga ttggagaata
    21301 gccctgtaca ggcagattca ggagctatag gaggttctac atcagccgaa tttatggtta
    21361 agtcagaagt tggtgaagat gaagttgtat tttgtagtgg atgtgattat gcagccaatg
    21421 tagaaagagc agaatcttgt aatctagcat cacaaaaaga agaaatgaaa gaattagaag
    21481 aggttcatac accaggagca gctacaataa aagagttaga agaattttta aaaacttctc
    21541 cagataagtt tgctaaaact ttagtatatg aggcagatgg aaaaacagtt gtagtcgttg
    21601 taagaggaga tagagaagtt aatgaaatca aagtatctaa tgccataggt tctgttatag
    21661 aatttgctct tgctacagat gatgtagtga gaaaagtaac taatgcagaa gtaggatttg
    21721 caggtccaat aggtataaat gctgactatg tatttataga taaagaaatt gttgaacaaa
    21781 gaaacatagt tgttggggct aataaaactg agtaccatat aaaaaatgct aactatggaa
    21841 gagattttga aggaatagtt ggagacttta gaaatgttca agaaggcgac aagtgtatag
    21901 tatgtggtaa gccacttgaa atagctagag gtgttgaagt aggacatata tttaaactag
    21961 gaactaagta ctcagaatct atgaatgcaa acttcataga caaagatgga aaatcaaagc
    22021 ctatagtaat gggatgttat ggaataggtg ttgaaagaac agcagcagct ataattgaac
    22081 aacataatga tgagaaaggt ataatatggc ctttgtcagt agctccatac catgttgtga
    22141 tagttccagc aaatatgaaa aatgaagaac aaatatcaat agctgaaaat atatataatg
    22201 atttgcaagc tatgggtgta gaagttttat tagatgacag agatgaaaga ataggtgtca
    22261 aattcaatga ttcagaatta ataggaatac ctatgaggat tacagtaggt aaaaatatta
    22321 atgaaggtaa agtagaattt aaacttagac ataaagaaga taaagagata attgacatag
    22381 aagaaataaa tgaaaaagta aaggcagagt ttatcaggaa taatgttagg ttaggataat
    22441 aacttaaata agatattgta tagataatca aagttgtact ttatagacac cattttatct
    22501 atatataagg atataaaatg gtgttttttt ataaaacaaa taaatgagga ggtaattaaa
    22561 atggcaaaaa atgaaaaaca atttgttgaa gaaataacaa agatggaaga tgattttcca
    22621 caatggtaca cagatgtaat aactaagact gacttagttg attatgcacc agtaaaaggt
    22681 tttatggttg taaagccata tggatatgca ttatgggaaa agatgcaaga atttatggat
    22741 aaaaaattta aagaaactgg acataaaaac tgttattttc cattattaat accagagagt
    22801 ttattaaaca aagaagcaga acacgttgaa ggttttgctc cagaagttgc atgggtaaca
    22861 catggaggaa ataaaaaatt agaagaaaga ttatgtgtaa gacctacttc agagactata
    22921 atatgtacaa tgtatgcgaa atggttaaaa tcatatagag aattaccata tctttataat
    22981 caatggtgct cagttgttag atgggaaaaa tcaactagac ctttcttaag aacatctgag
    23041 tttttatggc aagaaggtca tacattacat gaaacagcag aagaagcaca agaagaaaca
    23101 atacaacaat tagaagtata taaagcgcta tgtgaagaat tacttgcaat gccagttgta
    23161 gctggtcaaa aaagtgaaag tgagaaattt gcaggtggtg aaagaacata tactatagaa
    23221 gctatgatgc atgatggtaa agcattacaa tcaggtacaa gtcacttcct aggtcaacac
    23281 tttactaagg cttttgatat tacttttgca gatagggaag gaaatttagc taatccatac
    23341 catacatctt ggggagcatc tacaagactt ataggtggac ttataatgac tcatagtgat
    23401 aacagaggtt tagtattacc accaagagta gctccaattc aagttgttat agttcctata
    23461 gctgctaaaa aaggaaatgt aatggagact gttgataaaa tatatgctga tttaaaagct
    23521 aagggagtag ctgtagaagt tgatgataga gataactata caactggatg gaaatttaat
    23581 gagtgggaaa tgaaaggtgt tccagtaaga gttgaaattg gaccaaaaga tatagaaaat
    23641 aatcaagcta tggtatttag aagagatact ttagaaaagg attctatgcc tttagaagga
    23701 ttagctgatg ctatatgtga tttatttgat gttatacaca atgatatgtt tgaaaaagca
    23761 agaaaacata gagaagacaa tacatctata gttgaaaata tggatgagtt tagaaaagct
    23821 ttagaagaaa agccaggatt cataaagact atgtggtgtg gagatgcaga atgtgaagct
    23881 aagattaagg aagaaacagg agcaactata agatgcttac cttttgaaca agaaaactta
    23941 ggtcacaagt gtgtgtactg tggaaaagaa gcagatagta tggtagtaat ggcaaaagct
    24001 tactaaaata catttaaata aaaactgggg tagaaagtat ttaatacttt atcccagttt
    24061 ttttgttttt tatgagtaat aaaatgtatt tgtaactatg tcataagata agtcatagat
    24121 acttatatta aaaagaatat aatagagaac tatttttaat aattacatat taatgaaagc
    24181 aaaatatttt gttatataga ttttcaataa agcaaacaat aaatataaat gcatattaat
    24241 aaggagtgct tttaattttt agaaaataaa tgacttaaaa gaaagattta tgaaattaaa
    24301 actaggattt tctgatataa taaacatgtg tatttttaaa taaaaaggat attattatta
    24361 gatttgatta aaaataaact tgcaaaacaa tgtactagtt taatattata gttatattga
    24421 ataaaatatc aggaggaagt aaaaatgaat gtaagagtaa ggtttgcacc aagtccaaca
    24481 ggatttgtac atataggtag tttgagaact gctttatata actatttatt tgcaaaaaaa
    24541 atgggcggag aatatatatt aagagtggaa gatacagacc aaagtagatt agtagaaggt
    24601 gctatagaga atatgcttaa tgctatgaaa tgggctgggg tcaaccatag tgaaggtgtt
    24661 atattagatg atagtggaaa agtagtacaa aaaggagaat atggtccata tattcaatct
    24721 caaagattag atatatacca agaatatata aagcaacttt tagatagtgg aaaagcttat
    24781 tactgtttct gtacaaaaga aagactggat gaagtaagag atgctcaaag agcagcagga
    24841 gaaacagcta aatatgatgg tcattgtaag aatctttcta aagaagaagt agaagcgaat
    24901 ataaaagcag gaataccata tgttataaga ttaagattgc cagagaatca tacaattaag
    24961 tttacagact tagttagagg agatatggaa tttaatacta atgacttaga tgaccaagta
    25021 ttaatgaaaa cagatggatt tccaacttat cattttgcag tagttgttga tgactatttg
    25081 atgaaaatta cacatgttat aagaggagaa gaatgggtat catctactcc aaaacatgtt
    25141 tatttatatg aagcttttgg atgggaagca cctgtatttg tgcatttacc aaatatactt
    25201 aataaagaaa agaaaaaatt aagtaaaaga caaggtgatg tagctgttga agactttaag
    25261 aaaaaaggat atttaccaga gggattagta aactatgtag cattagttgg ttggtctcct
    25321 gaagataatc aagaattgtt tacaatggag gaattagaaa aagccttctc tgtagaaaga
    25381 gtatctaaaa gtggtggagt atttgatact gaaaaattaa attgggttaa tcagcactat
    25441 ataaaagatg gtgatgatgc ttatctaaca gacttagcaa taccattttt aatagaagat
    25501 ggatttataa cagaagaaga agctactaat aaatatgatt tcttaaagag tatgatatca
    25561 gtacttaaag agaaattaca atatgtaaaa gaagttactg aacatgcaag tatatttttt
    25621 ggagataaaa tagaggtaga aactgaagag ggaagagagt tcttaagatt agaacatata
    25681 cctactttaa tagatgcttt gagagaaaaa atagaaaaaa cagaggtatt aaatgctgag
    25741 tttgttcaag ctatgcttaa agaaatacaa aaagagtaca aaataaaagg gaaaaattta
    25801 tttatgggct caagaataat tttgacaggg caaatgcatg gtccagattt accaaaagta
    25861 atggaggttt taggaaaaga aacttgctta aatagaatag cttatgtaaa aaataatata
    25921 ttatagtcat aaaagtccgc taatttagaa gcggactttt tttgtgttag tatttggtga
    25981 aaatatctgc ttaagaaaat gaaggtattt aaggtaataa atttaatata taaaaagcaa
    26041 agcaaaaata taaataaaat atgaataata aactaataaa atattaagca tagaagaagg
    26101 gaatctatta ttttagtttg atttaattat taagggggta attactatgt atagtaatat
    26161 tgatgatgtt aaaaaggaat taaaggagct atgcttagaa tatgttacaa ttttagaaaa
    26221 attaaaagat gaaaaaatga ttacagaaga aacttttgaa aagtgctctt ctcaaaaaaa
    26281 aatattttta gaagaacaat agaggatggt aatagtatta ttattattat gtagtttgaa
    26341 agatagtacg aaaaatgata gtaatactat tatttattgc aattttcaac tataatataa
    26401 tatataatgt taagaagata atttataaaa atacagtgag gtgatgagtg tgaaagttta
    26461 taatacattg actagaacaa aagaagaatt tgttccatta gaagaaggaa aggtaaaaat
    26521 gtatgtgtgt ggtccaacag tttataacta tatacacata ggtaatgcaa gaccatttat
    26581 aatatttgat actctaagaa ggtatttaga gtatagagga tatgatgtaa cttatgtaca
    26641 aaactttaca gatgttgatg ataagattat aaatagaagt catgaggagg gaatatctcc
    26701 tgaagaagtt gcggctaagt atataaaaga atattttgta gactgtgatg ggctaggaat
    26761 aaaaagagct actgttcatc ctcaggttac agataatata caacagatta tagagtttat
    26821 aaaagagttg gaagataagg gatatgcata tgcagtaaat ggtgatgtat attttgatac
    26881 aaataagttt gaaggttatg gaaaactttc aggtcaaaaa caagaagatt tagaggcagg
    26941 ggctagaatt gaggttaatg accaaaaaag acatcctatg gactttgttc tttggaaggc
    27001 aaaaaaagaa ggtgagccag gatgggatag cccttgggga gaaggtagac caggatggca
    27061 tatagaatgt tctgttatgt ctaagagata tttaggtgaa acaattgata tacatgcagg
    27121 tgggcaagat ttaacattcc cacatcatga aaatgaaata gctcaaagtg aagctagaag
    27181 tggaaaaaca ttctcaaaat actggatgca taatggatat ataaatataa atgatgaaaa
    27241 gatgagtaaa tcaaaaggta atttctttac agtaagagat atatcaaaat tatatgattt
    27301 agagatagta agatttttca tgttatcagc acattataga aatccagtaa actttagtga
    27361 tgagatgtta aatcaagcta aagcaggtct tgaaagacta tataatacta aagaaaaatt
    27421 agaatttacg ctaagtaatt tagtagaatc tcctttaaca gaaaaagaag tagagcttgt
    27481 taaagaatta gatgacttta gacaaaaatt catagatgct atggatgatg atgttaatac
    27541 agcagacgca gtaagtgtaa tatttgaatt agctaagtta ataaattcta atgtagatga
    27601 aaattcttct ttggagtttg ctaaaaaatg cttagatgaa tttaatgaac ttacaggagt
    27661 attaaatatt gtaaataaga aaaaggatac tgtattagat aaagacattg aagaattgat
    27721 acaaaaaaga actgatgcaa agaaaaataa agagtttcaa ttagctgatg atattagaca
    27781 acaattacta gatatgggaa ttgtattaga agacacaaga caaggtgtta agtggaaaag
    27841 gatataaaaa tggaaaaaac tgaattagtt actatgtcac cattagtttt agcatactta
    27901 ggtgatacag tgtatgagac atatataaga gaatatttaa ttagacagaa tacacaaaga
    27961 aaagttaatg atttgcataa actagctata aagtatgtaa aagctaaagc tcaggcaact
    28021 ataattcatg aaattgaaat tgagttaact gaagaagaga gtaaaattta taaaagggga
    28081 agaaatcaaa agtcaaatac ttctcctaag aatgcagata ttatagacta caaacatgca
    28141 actgggtttg aggcattagt tggatatttg tatttaaata atgaaataga gagacttcaa
    28201 tatattatca ataaaggaat caaaattatt gaaagagata tgtaaatatt aaagagtgtt
    28261 gtcttaataa taagtaataa ggcaacactt tttttataac taatgtataa taaatatata
    28321 gaaattagta atgagaaagg ataaaaagtt atgaaagtaa aattaatatc acatacacct
    28381 gaaccagaaa aagtaatagc tatggcagct aagctatgtt attcaccagt tgggacagac
    28441 gaaatagaaa aagacttaac agatgaaagt atagagaaat ttttaaatat gttattaagt
    28501 ataggtcatg ggtcaatatt agaacatgct tcatttacat tttcaataga aggtatttca
    28561 agggcttgtt cacatcaaat tgttagacat cgtatagcta gtttttcaca acaaagtcaa
    28621 agatatgtta aattagaaca atttgagtac ataattcctc cagaaataga aaaaatagaa
    28681 aaggcaaaag agttatttat agactccatg aaaaaagacc aagagaatta tgataagtta
    28741 gttgaaatat tgtttgaaaa tcattataat gacctaataa aaaacggtaa aaatgagaaa
    28801 acagctaaaa gacaagctga aaagaaagca atagaagatg ctagatacgt atttccaaat
    28861 gcatgtgaaa caaaaatggt atttactata aatgctagaa gtttgtttaa tttctttgaa
    28921 catagatgct gtgaaagagc acagtgggaa ataagaaatt tagctgtgga gatgttaaga
    28981 gaggttaaaa aggttgctcc tatattattt aaaaagactg gtccaagttg tgtaaatgga
    29041 agttgtccag aaggaactat gacttgtgga gatatagttc aagttagaga aaaatttaag
    29101 gccttgtagg aggtgaataa tttggcgagt atagaaggaa gaaatccggt aatagaagca
    29161 ataaaaagcg acagagaaat agataaaata ttaattgcaa attcagctaa agaaggttca
    29221 attaagaaaa taataggaat ggctaaagat aagaatataa ttattcagta tgttgataaa
    29281 cataagttag atgaagtaag tacaagtcat tcacatcaag gtgtaatagc ttatgcaagt
    29341 gagtataagt attatgaatt agatgagcta atagatttag caaagaataa agatgaagac
    29401 ccatttttca ttatattaga tgagataaca gacccacata atttgggttc aataataagg
    29461 acagcagatg cagtaggagc acatggagtt atcattccaa aaagaaggtc tgtacacata
    29521 actcctgtag ttgccaaagc atctgctgga gcagtagaat atatgccagt ttgcaaggta
    29581 accaatatag ttaatacaat aaaaagactc aaagaagaag ggctgtggat tgctgcagct
    29641 gatatggatg gagaaacttt ttataaacaa aatcttactg gtcctcttgg tgtagtaatt
    29701 ggaagtgaag gttttggaat atctagattg gttaaacaaa actgtgactt tatagtaaaa
    29761 atgccaatga taggtaatgt tacatcttta aatgcatctg tagcaggtgg aatactttta
    29821 tatgagatat tcagacaaag actggataaa agtaaatagg catgaaaaaa aatataaatc
    29881 attacttaat aatagatggc tacaatatta taaatgcgtg ggacaatttg aaagaactgg
    29941 ctaaagagga cttagaagat tctcgagaaa agcttattga tgacattata gaattttctg
    30001 agtttatggg ttataagact ataatagttt ttgatgctta taatgttaaa aattctcgag
    30061 aaaaagttga aaaaagaaaa cacataacaa tagtttatac aagagaacac caaacagcag
    30121 atagttatat agagaaattt ataacttctt tatcaaagta tgatgatgta aaagtagcca
    30181 ctaatgacta tgcagaacag caaatgattt taggaaaagg tgctactaga atgtctgcaa
    30241 gagaattaaa gttagagtta gatcgttcca agaataaaat gaaggaaaaa aatatcggtt
    30301 tgaggaaaaa aattcagcga aattggttgg aggaaaggtt agataaagaa acattgtcga
    30361 aacttgagaa cattcgtaga aagcgttgaa attactaggt tctttagact ataatatacc
    30421 tataaatttg ttttatatat gggggagatt tacatgttgg tagcaaaaga aaaaagttat
    30481 gagttagtgg acaattgtca gcaggatgag tataacattg tattaagagc aagtgaaggg
    30541 gataaaatag cactagagta cattattact aaatacagaa attttgtaaa ggcaaaagca
    30601 aagtcatatt ttttaattgg agcagataaa gaagatataa tacaagaagg aatgataggc
    30661 ctttataagg cagttagaga ttttgatgga agtaagacca attcatttaa atgttttgcg
    30721 gagatatgta taacaagaca aataataact gctataaaaa ctgcaacaag acaaaaacat
    30781 atacctttaa attcatatgt ttctttgaat aaaccaatat atgatgaaga gtcagacaga
    30841 acacttttag atattatagc tacaagtata gtaacagatc cagaagagct tataattagt
    30901 aaagaagagt taaaaaatat agaatcaaaa atgaacgaat tgttaagtga cttggaatta
    30961 gaagtactag aattatattt aaatggaaag tcataccagt ttatagcgga caagcttaaa
    31021 agagatgtaa agtcaataga taacgcttta caaagggtta agagaaaatt agaaaaacat
    31081 cttgaaaaca gaaatgatta atagtaaaat acttaccata agcttattgt gagcaaaatt
    31141 aatttatatc gaaagataag ggaggaaatt caaaatggct aaagctaaat acgaaagaac
    31201 aaaacctcat gttaatatag ggacaatagg acacgtagac cacggtaaaa ctacattaac
    31261 agcagcaata acaaaaacat tatatgacag atatcaatta ggagaagcag tagatttcgc
    31321 aaacatagat aaagctccag aagaaagaga aagaggaatc acaatatcaa cagcacacgt
    31381 tgagtatgaa acaccaaata gacactatgc acacgttgac tgcccaggac atgctgacta
    31441 cgttaagaac atgataacag gagcagcaca aatggacgga gcaatattag tttgttcagc
    31501 aacagatgga ccaatgccac aaacaagaga gcatatacta ttatcaagac aagttggagt
    31561 accatatata gtagtattct taaacaaatg tgacatggta gatgatgaag agttattaga
    31621 gttagtagag atggaagtaa gagatttatt aacagaatat gatttcccag gagatgacac
    31681 tccaatagta agaggttcag cattaat
//
LOCUS       DAMKNB010000038        30956 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.040, whole genome shotgun sequence.
ACCESSION   DAMKNB010000038 DAMKNB010000000
VERSION     DAMKNB010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 30956)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30956)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30956
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.040"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            401..2635
                     /locus_tag="PC494_002028"
     CDS             401..2635
                     /locus_tag="PC494_002028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HDF3912529.1"
                     /translation="MQNHNYIKMLNKKVEVLSKELDSRNFKLKTLNEIDFFSKIPNRE
                     FMYQHIDDCISKNIHIGIMLLNIDNFKLFNDIYGYLVGENLLITLTQNLLHFIPESKG
                     IVAYLKGEGFLIVLPNVSNKELNNMGATIIESARELKIKLPNEKEIYSNVTFSIGSTI
                     WNGEPNMTTLMLFNQVYSALKKAKSEGKNRYILFDFKDNSFYNKLENDKEFLSEISHV
                     LQTKQIEVFYQPLYNIKNNTIVGCEALARWRHPIKGLLTPDKFIPLFEQFGLITELDL
                     HLFEENCKNIRRWIDNNDVFVPICCNFSRLHFFNPNFPSMLKGITEKYSVSTSNFSIE
                     ITENILIENTNTIIQQLAELRSYGFSVSMDDFGSGYSSFGMLQNLPFDIIKIDRIFLS
                     HNLNDFKNTTILYSIINIARALGMLTVCEGVETEQHVEFIKSINCDIAQGYYYAKPME
                     CKEFEKLLSKENNSEKMFIKYSDIGKSLIEKIFDGFFIMQDMKKLRANVTEDIQWFDF
                     YNKTEITSFPKVIEHFEKHIKGKKFSILYKSITPHNTESDSLLISGEAVLSDEASEHQ
                     KYSNFYFSANCIISENKLLLAKLHLDLIKTAGYINEFESYSIPKMTNTHLDESNILSQ
                     FYSMLPVGIIRYDLFGDMIITYMNEEMFDIIGYTKEQFFGEMGGNLRAIVHPDDLDFV
                     YKKSLDMIDTNKIEPFLYRFIKRDGQIVTVMYTQCNLSAIDGRSIAQGMYVDVNKIKN
                     LTKI"
     gene            2666..3499
                     /locus_tag="PC494_002029"
     CDS             2666..3499
                     /locus_tag="PC494_002029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HDF3912530.1"
                     /translation="MFKEIFLRTFPGFLIIRDSNYRIIFINDNLKNLIKSYMQDNPLG
                     MTNIEIAKKLPDNIAKFFTDSHNIQLDWEKNYPYDKISNWILEFKKDTTSYWNVLEYK
                     VDVDEKTYIITMANDITKLYEENKRNLHYSITDPLTGAYNRKYLNDRFDIFIGDYIVL
                     IDLDNFKMINDYEGHNVGDKILCDFVSLLNKELINSTSIIRLGGDEFIVIFSSDVDKN
                     YVYSQLEALRENFLKVFSKYKYLSFSYGVDTVKRNLKLTIVELDKKMYKNKKKFDKND
                     Y"
     gene            3739..5472
                     /locus_tag="PC494_002030"
     CDS             3739..5472
                     /locus_tag="PC494_002030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HDF3912531.1"
                     /translation="MSILLKKAPKLAKHIITSFYINRDIDEVLKYLCENVTWIGPGEQ
                     EFLTSFNEIKNYFYAGQDEIPSCDINNDIFETVSEDENRCMVLGRYTVRTKENTQMIL
                     EVNQRCTFEIIEDRGKLLVKHMHISNPYGEMQLDEYFPTKIGTQSYDYLQRLLKEKTE
                     VIEMITNNINGGLKGSNDDNTYSFFYVNEGLPKILGYTYDEFMEMSGGSAVGAVYPPD
                     LPKALEDCERCFAKGPTYSSEYRIRKKDGTLMWVLDSGMKSLNSDGIVKINSIITDIT
                     QLKNIESELKLERERYRIALQNITDIMFEYDIENDTLIKYQRVEIDKKIELENFETKN
                     YSKLLESGKIIHLDDIGKLLEVLHGNLRETIEIRQVNSLTKNEWRWIRVQCSVIYDSD
                     HNPIKTIGVLKDITEDKSKLESLINQAQRDPLTQLYNQRVSQNLIEEYLCSSDSKNND
                     ALLVIDIDDFKTVNDTFGHLEGNEVLVAVSKILLHNTHDKDIVARIGGDEFTIFIKSL
                     TKDLIIKITNDILNDASKIKVKDNHKITLSIGIAFTDDSTKLYKDLFSKADKALYLSK
                     ADGKNCYSTYE"
     repeat_region   5864..6158
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=5933..5961
                     /rpt_unit_seq="atttacataccacttagttaatataaaac"
     gene            complement(6688..6792)
                     /locus_tag="PC494_002031"
     CDS             complement(6688..6792)
                     /locus_tag="PC494_002031"
                     /inference="COORDINATES: protein motif:HMM:NF024729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HDF3912532.1"
                     /translation="MDDYIYYYNNFRYQNRLNSMSPFEFRKYLSTERA"
     gene            7417..7662
                     /locus_tag="PC494_002032"
     CDS             7417..7662
                     /locus_tag="PC494_002032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3912533.1"
                     /translation="MNQKKIKISIKMVIIGIFAVIIAFVLSRLFVEYIDELLRSNWQY
                     QLFESESSYIVFANCIMFSNILLEIFLIYICRKFRKI"
     gene            complement(8415..8561)
                     /locus_tag="PC494_002033"
     CDS             complement(8415..8561)
                     /locus_tag="PC494_002033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3912534.1"
                     /translation="MVFETFDKTIELYPNAKPIFHSDIGFRLDDESFEEYLGRVFRKR
                     CKGI"
     gene            8657..9306
                     /locus_tag="PC494_002034"
                     /pseudo
     CDS             8657..9306
                     /locus_tag="PC494_002034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429361.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase family
                     protein"
     gene            9847..11202
                     /locus_tag="PC494_002035"
     CDS             9847..11202
                     /locus_tag="PC494_002035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HDF3912535.1"
                     /translation="MDTKISINENMSLGKRFFKYLAPSVVAMWVFSLYTMVDGIFVSK
                     GVGELALAAVNISMPFINFIFAVSLLFSTGASTIIAIYLGKKDIKSANEVFSFNLVSI
                     IILSIIILAITFFNLDRLALFLGATESTIGMVKDYLGIIIFFNGFFIVSYSLEVIIKT
                     DGFPILATVGVIISALTNIILDYLFVIEFGWGVKGAGIATGLSQVFSTIFFLIHFLRK
                     NSTLNFSKFRIDFKTLRKIVFIGFPDSTTELSCGIVVLLFNLSLTKYIGENALIYYSV
                     INYINTLVLMTMMGITQGMQPLTSFYYGAGNIDNVKKLLKMGIKATIIASVAVFAICM
                     AFSGPIVSLFIHPEETMLFNEGVRVFKIFSISFLLVGINVIISGFFVSVEKPSISTVI
                     SLGRGLVIVVLSLISMILIFGGQGIWMTTIVSEFICLILSLVFLKKNFSTLDSNLNKV
                     A"
     gene            complement(11320..11988)
                     /locus_tag="PC494_002036"
     CDS             complement(11320..11988)
                     /locus_tag="PC494_002036"
                     /EC_number="6.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphthine--ammonia ligase"
                     /protein_id="HDF3912536.1"
                     /translation="MKEVLKLADEKFVMSFSGGKDSILALNRMLKKGYKPVALLTTIS
                     EEHGKSWTHNLEYNMLKQVSSNIGLPLLVAECGVEGYEESFERALIKAKNMGATICAY
                     GDIDIESHRKWDTDRCEAVGMKVDLPLWQESREDLVYEFIDSGFCSVVTKVNLKHLGE
                     EFLGKKLTRELVEKIKNAGADPCGEHGEYHTFVVDGPIFKKPVEYEVKGTLIKDGYGY
                     LEIK"
     gene            complement(12055..12483)
                     /locus_tag="PC494_002037"
     CDS             complement(12055..12483)
                     /locus_tag="PC494_002037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HDF3912537.1"
                     /translation="MTKLWAIIFALLAGGSTALEAFINGELGKSTTALVATFISLTVG
                     AIFFLASIIVTGDLKCLVSINGFNYKLLLGGVFGGLIIYFTVKAIPNLGVSNTLILTL
                     VSQVLVGFFIDSVILGQETMHLYKYIGVILLILGTFFIVN"
     gene            12590..13183
                     /locus_tag="PC494_002038"
     CDS             12590..13183
                     /locus_tag="PC494_002038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF308 domain-containing protein"
                     /protein_id="HDF3912538.1"
                     /translation="MNFCYNCSIDFGGDFMYTNFNIDFNNFNKKENAIKFMLMGVLLI
                     ILGLLCLTFKTLGIKLISWTFGIALLFFAYLNLKNINELKRYATKEEIKPSINIQWVL
                     IIACILLFVFPQKIQSIFSLFLGFYLIFNQLVALVNSKNNPYSKFTTWNIVKILFGIC
                     LILSPLFLSRFIVSIMSFFIILFGLVLFFSGNTARKY"
     gene            13302..14237
                     /locus_tag="PC494_002039"
     CDS             13302..14237
                     /locus_tag="PC494_002039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893027.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
                     /protein_id="HDF3912539.1"
                     /translation="MDKFKYAFDNKRYHTWNYYLRNTFGEKVFKVSINAGFTCPNIDG
                     SLGYGGCTYCSKEGSGDFAGNPKDNLISQFYNIKEMMLKKWPHAKYIGYFQAYTNTYA
                     PLEVLKEKYETILELEDVIGLSISTRPDCLPDDVVEYLSELNKRTNLWVELGLQTIHD
                     STSKIINRGHDYKTFVEGVEKLKSKNIKVVVHIINGLPGEDYNMMMETAKAVGKMGVD
                     GIKIHLLHVIKDTPMEKMLQNGMLTLMEQDEYINLVCDQLEILPETMIIHRLTGDGKR
                     DELVGPIWSLKKWEILNQIDDTLKARNSYQGCKFV"
     gene            complement(14509..15453)
                     /locus_tag="PC494_002040"
     CDS             complement(14509..15453)
                     /locus_tag="PC494_002040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HDF3912540.1"
                     /translation="MGEKSKGYVFIAIAGLLWATLGLFGKFLMGNGLTSEQVAFTRLF
                     FGFIVLGVYSSIRTPQILKISKKGIIYSVIIGIICQAMFNLCYFKAIDIAGVSIAAVL
                     LYTSPLFLAIFSKICYKENITRSKLFSLILCFIGAIMAVTGGRLDFQGLNAFGLLLGV
                     LSAIAYALMPTISKNALKEFSSSTILVYSFLFGAIFMIPSSRPWEILNYAKDLDVLSC
                     MLMLGIVPAALAYIFYAAGISKGVELSVAGVVASVELVGSVIIGCTILGESFSLGKLF
                     GVMLMLISAVVALNLSYDEIRIFYKSNKLKQIEKTESI"
     gene            15771..17201
                     /locus_tag="PC494_002041"
     CDS             15771..17201
                     /locus_tag="PC494_002041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDF3912541.1"
                     /translation="MNLDLEFYQKILEASHDEICVSDDKGIIIYCNKAFEENYGLKKE
                     DILGKNVSFLEDSGYSTKSPIPIVLKTKTKFSLEQDTQTGKKLIITATPIFDENGNLE
                     FTVENCRDITELNNIKNKLEDTKKQVKKYKSEVETLYRTALRIEDTVIMDGIVMRPII
                     NTVNHVSKTDVSVLLLGESGTGKSSLARYIHHNSNRSNGPFITINCATISPQLLESEL
                     FGYTSGAFTGASTKGKVGLVELANGGTLFLDEIGDIPQNLQAKFLQLIQDRTFTPVGS
                     LKNKKVDIRIISATNVDLVSKVKEKKFREDLYYRLNVIEIKLPPLRERRDNLVEIIKY
                     YFNRYSSDFNLNKTISKEAMDAIANYRFPGNIRELQNIIQKILLTCTDNHITIDDLPN
                     ILTKNIHITNNGNKTHISQINKVIISDSKSTNYKNKNFDTLIKEYEKNIILDAYEKFG
                     SSYKVAKHLEISQSKANRLIRKYTNT"
     gene            17401..17985
                     /locus_tag="PC494_002042"
     CDS             17401..17985
                     /locus_tag="PC494_002042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc dependent phospholipase C family protein"
                     /protein_id="HDF3912542.1"
                     /translation="MLMNTHFIMAKSILDNIDENKTFFISEKNFIYGNIKPDAFSKYK
                     LKKHYLDESFNMIVSKINYLCSLNIDSLSKYFSVSRLSQELGVICHFLCDFFCVAHSE
                     RWEFKHSLNKHVTYERELGAFAKDVDLSKIKCGTINSSFEKFFTKLYSDYKKKTDYMN
                     DLKFSAYTCNSVINYILDSILSNTIKSYHIANCG"
     gene            complement(18089..18868)
                     /locus_tag="PC494_002043"
     CDS             complement(18089..18868)
                     /locus_tag="PC494_002043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HDF3912543.1"
                     /translation="MIKHIFCDLDGTLYENGTITKEDIVAIEEIEKKGVQFNVATGRI
                     FKQAHNIIKDSLDMNGYYVCENGSFIYDKDYNVIFKRTIDDNLVKKVIDRFESSDAQL
                     YFKYKGDVIVGSDTTAFRHYSSDFIVDPDFEKRSSFDNLIGNIGVCSENLEELSRIEL
                     YLKSEFSEVLEIYFSGTYTLNIVPKSVSKRGSIEHVIKTLNVSPDEVATIGDSPNDIC
                     MLEGFKYSFAMSKAREDVKQSANYVVDSVKSAIDVIMEINS"
     gene            complement(18926..20182)
                     /locus_tag="PC494_002044"
     CDS             complement(18926..20182)
                     /locus_tag="PC494_002044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011591286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HDF3912544.1"
                     /translation="MKAEIISVGTEILLGDIVNTNSQFLAKELASLGIEVYHQSTVGD
                     NKQRLLECFDESLKRSDFVITTGGLGPTGDDMTKETAAEYFGQKLELHKPSLEVLESF
                     FVKTGKKMAENNMKQVYFPKDAIVLKNNNGTAPGAILKKDGKFIIVLPGPPREMKAMF
                     NESVKPYLQQFTNEMLVSKTLRLYGIGESNLELEILDIINEQTNPTVALYAKELEVTI
                     RITAKAENEREAFKLIKPVEEKIKSRVGKYVYTEGDISISEGETALEDAVSKLLVEKN
                     LTIAVAESCTGGLVSSSLINYPGISSVFLEGCVTYSNDSKMKRLGVKRETLEEFGAVS
                     EQTAIEMAEGVAKGLKANIGISTTGVAGPGGGTKEKPVGLVYTAIYINGKTIVKKNIF
                     NGDRRKIRLRATRDLLNELRIQLEKL"
     gene            20440..21339
                     /locus_tag="PC494_002045"
     CDS             20440..21339
                     /locus_tag="PC494_002045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HDF3912545.1"
                     /translation="MKIAVIMGGISSEREVSLNSGKEIYNNLDKNKYEVVKVIIDDKK
                     DIFTKIPEDIDFAILALHGKFGEDGCIQSILETMDIPYSGCGPLCSGMCMDKNITKKM
                     LRDSNLPTAPWVLVKSVDEIDYDEIDNIGYPVFIKPNSGGSSVATFFIHSKDEVEEAV
                     RKGLEVDEFVMIEKYIPGGEYTSFILNGEVFPTISIKSDSGFFDYEAKYSVEKGAKEE
                     VVYLDEELQKRVNEISETCWKIFNCKAYVRVDMIISEGIPYVLELNTLPGMTQTSLIP
                     RSAAARGIKYSELLDKLIEYSLN"
     gene            21363..22811
                     /gene="ddlR"
                     /locus_tag="PC494_002046"
     CDS             21363..22811
                     /gene="ddlR"
                     /locus_tag="PC494_002046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator DdlR"
                     /protein_id="HDF3912546.1"
                     /translation="MIFSNLKLNDNEPIYIQLKNYISDMISKGLIPDNSKLPSTRELS
                     QLLQVSRNSVVLTYEELKSEGLIYSISGKGTFVKSKNKSSNTTWSLNWDCLENTYSKK
                     ANELDIIKSEIPWSSDLISFKSISPDGDLFDIEELKKSFLNRISLEGHKLLNYGYAQG
                     YKPLIDYLLEYMTNKGADISNKDILITNGFTEGFDIIMSSFTQEKDYIICENPTHNTA
                     IKIMKSHNLNILGVDINEDGLDFNMLEDNLVKYKNKIKFAYITPSYHNPTGIVMTPEN
                     RYKFYNLMKKYNIAIIEDGFNEELLYNSSHIFPICSLDNMNNGVVYIGSFSKILFPGM
                     RIGWIFADKKVINKLESVKRCRNIHVSFLDQGILFDYLSNGGFEKYIKKIRKFYGDKF
                     NFAYKCIKKYIKTEYILGDGGLHIFIKLKNIDTRVLLEKCYEKNVIFMPGDLFFTDNS
                     GFDTLRLGFSRLSFEDIEIGIKIIGETINEMF"
     gene            22870..23676
                     /locus_tag="PC494_002047"
     CDS             22870..23676
                     /locus_tag="PC494_002047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HDF3912547.1"
                     /translation="MNLILGDNMSKKSKRRKINKLKLTIVITVLFLALLSIYEILFSN
                     PNKKGNIKSQETMQNKNNTTDDSKNNQSSTKKQEDNNIKPTFSYSSIPDNIKNKMIGK
                     SMPTDEPISFDSLSYLKLTYYGFDEKTHQGEMIVNSELAPEVVDIFKELYEKKYPIEK
                     IKLIDDYDAVDEKSMSDNNTSSFCYRTIAGTNVVSNHGKGRAIDINPLQNPQVSGNDV
                     TPKVSTVYADRSSTKFGMIKKGDDCYNAFVSRGWSWGGYWKNPDYQHFEK"
     gene            23702..25621
                     /locus_tag="PC494_002048"
     CDS             23702..25621
                     /locus_tag="PC494_002048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_071223118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HDF3912548.1"
                     /translation="MNLMTLENISKSYSEKKLLENISLGINEGEKIGLIGVNGTGKST
                     LLKIIAGVEESETGNITKTNGIRIEYLPQNPTYNENSTVLEQVFNGTSEELKLLGEYQ
                     EILEKLNSNFTEELNKKLLSVHEKIDALNLWDLESEAKSVLTKLGINDFNQKIAELSG
                     GQRKRVSLASALITPCEFLILDEPTNHLDNDTIDWLEEYLNSRKGSLLMITHDRYFLD
                     RVTNRIIELDKGRLFSYDGNYSIFLEKKMERLSLEASIEDKRQNLIRTELAWVRRGAQ
                     ARSTKQKARLQRFDELINRDSFKPDENLDISVASSRLGNKIIEIHNISKSFEENTVID
                     NLEYTLTRTDRIGIIGKNGMGKSTLINILNGEIEPDSGYISIGETVKIGCFSQDDSHM
                     NIDMRAIDYVKEASDYIETSDGTRITASQMCERFLFNGTMQYTLIGKLSGGERRRLHL
                     LKILMTAPNVLLLDEPTNDLDIETLKILEEYLDEFKGVVVTVSHDRYFLDRICNKIFA
                     YEGNGKIHIYTGNYSDYLIYREIQGIEFEESKRESVKKDDSTTPKKEKPKNDKKLKFS
                     YNEQREFENIDSDIEKLESKIATLDESTAKFSTDFTKLQEILDEKSKLEKELEYKYER
                     WEYLNNLADEIANNK"
     gene            complement(25863..26210)
                     /locus_tag="PC494_002049"
     CDS             complement(25863..26210)
                     /locus_tag="PC494_002049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PqqD family protein"
                     /protein_id="HDF3912549.1"
                     /translation="MSKSNDVLDIVFKITDGLEYEVAENRVVTILEKQDHKIQKFFRK
                     LKARIPKYKKIELDEYSSFVFLQIDGQRTVREIGKNLEAKYGEESHPLYERLLVFLNH
                     IEVNCHYIERLDI"
     gene            complement(26197..28125)
                     /locus_tag="PC494_002050"
     CDS             complement(26197..28125)
                     /locus_tag="PC494_002050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide transporter, OPT family"
                     /protein_id="HDF3912550.1"
                     /translation="MNKKLPKGAYGEVSGKDYVPYITDKSRTGGNVAVLIIGIILAAI
                     FAASTTYSGMKAGLTVAAGIPGAIIGSAFVGAFARSKGILGKNLIQGMSSGGESVASG
                     FIFVLPAVILIGSQITFLEGLAVGVGGVLFGIGIAAIVHNYLIVEEHGKLMYPESMAI
                     SETLVASEAGGDSIKYMGIGFVISGFITVLTGSFLNVANNVMSLVGSKFYKWKFDIEV
                     NPLLLGIGFIVGLEVSLTMFAGSILSNFGIAPLIGYFTDMAKDGAMVWNNPAMPLNQM
                     DVGAISSSYVKYIGAGMMLCGGIIGAIKLIPTIIASIKETLKAKSSAGEGEEGSSIQM
                     ILLLGGVVIGFLAAFLISGNIVMAIIGAIISLLLSLLFVIVAGRLTGTIGTSNLPVSG
                     MTIASLVIVTLVFVIMGWTDLEANKSLLLFGSFIVVAIAIAGGYTQSQKVTYIIGGSK
                     NEMQRYFTIASIVGVIVVVGVILLLSDQLRATGDNVQFALPQANLMSTLTSGIMSGSL
                     PWVMIIVGVFMAIVLYALNLPIMTIAIGFYLPIATTSIILVGALIRLFVELVSKTEKE
                     KEVKVSNGISLSSGLVAGGSIIGLIGIILQVTGVVTPKVPSGFAATNSMAIALLVVLV
                     VLTALPIVLSKVKNNEQE"
     gene            complement(28537..30726)
                     /locus_tag="PC494_002051"
     CDS             complement(28537..30726)
                     /locus_tag="PC494_002051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid adenylation domain-containing
                     protein"
                     /protein_id="HDF3912551.1"
                     /translation="MYEVNLERAMNYWMDLLDDYTNIAKIPNDFFYKDCSDEVVDEVF
                     KMNIEKHERLIQYSKVNNISIDSIIETIYGLILQKYIYEDDVVFGKTMNIIPIRVRVR
                     QSEKFIDVVRKLKRQWSRSLEYGYYLLSDIENKNHLNTKLINTIFIAKSFDLSYDYDI
                     EKKGYDLSVIVYTKRALKIKIKYKPSIYKRETIRRILNQFDYIIEQIIEDNDILIEDL
                     EFVCKEEEKVLLEDFNNNQYEVPYDKSYVDLFREQVKVTPSNIAARDENRKLTYKELD
                     EVTDKLAGYLNHIGVESEDIVAVMLPRDINIIITAIGIMKSGGAFFPIDTSNPEERLN
                     YLLEDSNAKVVITTDELKSKVVNENTIVLDINDEEMFKFGYELTEKITSSNCAYTIST
                     SGSTGRPKTIAIEHKSLVNMCYYSVKSISATENDICGIYLSFSFDAVMKQLFPYLLVG
                     ASIDIMPEEAKFDEYTVNEYCEENDITILALPTAFARLFIQNCNNNSLRVVQTGGERL
                     KGYRKRNYELYNEYGPTEFTVVSTSFHVDREYGKIPIGKPIFNTYAYVLDKKNKLCPI
                     GAPGELCLSGIQISRGYLNKKGLTEQVFVENPYKTCEHNKLMYRTGDLVRWLDDGNLD
                     YIGRMDNQVKIDEFRIELYEIENIINNITEIKSVVCISRTNDDGDIYICAYYVIDEED
                     SGKINERTIREYLNEHLPPYMIPTIIMRIDKIPVTPIGKVNKRALPE"
BASE COUNT        11631 a         4341 c         3947 g        11037 t
ORIGIN      
        1 attattaata tggtattaaa ttatgtataa aaagttaatt atgaataaaa taattatgcc
       61 tttgaaaaat cattaaactt aaaattaatt ataaaaaaac tctaccttac taactataca
      121 gctcacaatc tatctattta tgaaaaaata tgatataatt gcattcaaaa aggaaatctt
      181 tcaatatact agaatttaag cattaactaa ttttatctaa tattattact aaactaaaaa
      241 atatttgtat ttgtagcatt ggagcaagta acttaatgta tattcatttt aaatacttat
      301 ttaaaattta gcatttaaat tatttacaaa ttaacattta aatacttcta gcataaatac
      361 agttgtcatt aaaatttaaa gtatcttatg gaggaatacc atgcaaaatc ataattatat
      421 aaaaatgtta aataaaaagg tagaagtatt atctaaggaa ttagatagta gaaattttaa
      481 attaaaaacc ttaaatgaaa tagatttttt ttctaaaata ccaaacagag aatttatgta
      541 ccaacatatt gatgactgta tttcgaaaaa tatacatata ggaatcatgt tattaaatat
      601 cgataacttt aaattattta atgatatata tggataccta gtcggagaaa atttattaat
      661 tactctaact caaaacctat tgcactttat tccagaatca aagggaatag tcgcttattt
      721 aaaaggagaa ggttttttaa ttgtacttcc aaatgtatca aataaagagt taaataatat
      781 gggtgcaact attatagaga gcgcccgaga attaaaaata aaacttccta atgaaaaaga
      841 aatatactcc aatgttacat ttagtatcgg cagcactatc tggaatggtg aaccaaacat
      901 gactactttg atgcttttca accaagtata tagtgcttta aaaaaggcta aaagtgaagg
      961 taaaaataga tacattctat ttgattttaa agataatagt ttttacaata aattagaaaa
     1021 tgataaggag ttcttatcag aaatatcaca tgttctacaa actaaacaaa ttgaagtatt
     1081 ttaccaacca ctttataata taaaaaataa tactatagtt ggatgtgagg cacttgcaag
     1141 atggagacac cctattaaag gacttcttac tccagataaa tttattcctt tatttgaaca
     1201 gtttggtctg ataacggaat tagatttgca tttatttgaa gagaactgta aaaatataag
     1261 aagatggatt gataacaatg atgtttttgt tccaatttgt tgtaactttt ctcgtcttca
     1321 tttttttaac cctaattttc caagtatgct aaaaggtatt actgaaaagt acagcgtctc
     1381 tacatcaaat tttagcattg aaataacaga aaatatatta atagaaaata caaatacaat
     1441 tattcaacaa ctagctgaac ttcgttctta tggtttttct gtatcaatgg acgattttgg
     1501 ttctggatat tcatcttttg gtatgttgca aaatctacct tttgatataa tcaaaattga
     1561 taggatattt ttatctcata atttaaatga ttttaaaaat acaaccattt tgtactctat
     1621 aataaacatt gcaagagctc ttgggatgct tacagtatgt gaaggtgttg aaacagaaca
     1681 acatgtagaa tttattaaaa gtataaattg tgatatcgcc caaggttatt attatgcaaa
     1741 acccatggag tgcaaagaat ttgaaaaatt actatctaaa gagaataatt cagagaaaat
     1801 gtttataaaa tattctgata taggaaaatc tttaatagag aagatatttg atggattttt
     1861 tattatgcaa gatatgaaaa aactaagagc taatgtcact gaagacattc aatggtttga
     1921 tttttacaac aaaactgaaa ttacatcttt tcctaaagta atagagcatt ttgaaaaaca
     1981 tattaaaggt aaaaaatttt ctattcttta caaaagtata accccacata atactgaatc
     2041 agattcatta ttaattagtg gagaagccgt tttatcagat gaagcttctg aacatcaaaa
     2101 atatagcaat ttctacttta gtgcaaattg tataatttca gaaaataaat tactcttagc
     2161 aaaattacat ttggatttaa ttaaaactgc tggctatata aatgaatttg aatcatattc
     2221 aatacctaaa atgacaaata cacatcttga tgaaagtaat attttatcac aattttattc
     2281 aatgttgcct gtaggtataa ttcgctacga tttatttggt gatatgatta ttacttatat
     2341 gaatgaagaa atgtttgata ttataggtta tacaaaagaa cagttttttg gtgagatggg
     2401 cggaaattta agagcaattg ttcatccaga tgatttagac tttgtttata aaaaaagttt
     2461 ggatatgatt gacacaaata aaattgaacc atttttatat agattcataa aacgagatgg
     2521 tcaaattgtc acagttatgt atacacaatg taacctttct gcaattgatg gaaggtcgat
     2581 tgcccagggt atgtatgtag atgtaaataa aataaaaaat ttaacaaaaa tctagtacaa
     2641 agtattttat tttggagaaa ttaatatgtt taaagaaatt tttttaagaa cttttccagg
     2701 atttctaatt ataagagatt ctaactacag aattatattt ataaatgata atttaaaaaa
     2761 tttaattaaa agttatatgc aagataatcc acttggaatg actaatatag aaatagctaa
     2821 gaaactccct gataatattg ctaaattttt tacggattct cacaatattc aattagattg
     2881 ggaaaaaaat tatccttatg ataaaatttc aaattggatt ttagagttta aaaaagatac
     2941 tacaagctat tggaatgttt tagaatataa agtagatgtt gatgaaaaaa cctacataat
     3001 tactatggcc aatgatataa caaaactcta tgaagaaaat aagagaaatc ttcactactc
     3061 aattactgac ccattaactg gagcatataa tagaaaatat ttaaatgata gatttgacat
     3121 atttatagga gattatattg tactaattga cttagataat ttcaaaatga taaatgacta
     3181 tgaaggtcat aatgtaggag acaagatttt atgtgatttt gtttcacttt taaataaaga
     3241 attaataaat tctacttcta ttataagatt aggaggagat gaatttattg ttatattctc
     3301 tagtgatgtt gacaaaaatt atgtttattc acaactagaa gccttaagag aaaatttttt
     3361 aaaagtattc tctaagtata agtatctttc atttagttat ggtgttgata cagtaaaaag
     3421 aaatttaaaa ttgacaatag ttgaattgga taaaaaaatg tataaaaaca agaaaaaatt
     3481 tgataaaaat gattattaat attgttattt taaaataaat taaaattatc tttctttttt
     3541 taaacttgta cattagttta taaatatgta tctatacaag atattgacat taagtactga
     3601 agcatatatt gtttcagttc ttttttgtta aaattaactt atttaacaaa gatatcatag
     3661 tttaacaaag cttttaattt aaatatattg atgtataata taattaaaat ataatagcaa
     3721 aaagaaagga ggaatatcat gagcatactc ctaaaaaaag cacccaaatt agcaaaacat
     3781 attataacaa gtttttatat aaatcgggat attgatgaag tattaaaata cctttgtgaa
     3841 aatgttacat ggatcggacc aggagaacag gaatttctca cttcttttaa tgaaataaaa
     3901 aattattttt atgcaggtca agatgaaatt ccttcttgtg atataaataa tgatatattt
     3961 gaaactgtaa gtgaagatga gaatagatgt atggtattag gaagatatac tgttcgaact
     4021 aaagaaaata ctcaaatgat tttagaggta aatcaacgtt gtacatttga gataattgag
     4081 gatagaggaa aattattagt aaagcacatg cacatatcaa acccttatgg tgaaatgcaa
     4141 cttgatgaat actttcccac taaaattgga actcaaagtt atgattattt gcaaagatta
     4201 ctaaaggaaa aaacagaagt tattgaaatg attacaaata atatcaatgg tggcttaaaa
     4261 ggtagcaatg atgataatac atactcattt ttctatgtca atgaaggatt gcccaaaata
     4321 ttaggataca catatgatga gttcatggaa atgagtggtg gttcagcagt gggtgctgta
     4381 tatccaccag acttacctaa agcactagaa gattgtgaac gatgttttgc aaaaggacct
     4441 acatattcat ctgaatatag aatccgaaaa aaagatggaa cattaatgtg ggtattagat
     4501 tctggaatga aatcattaaa tagtgatggc atagtaaaaa ttaatagtat tattactgac
     4561 ataacccaac taaaaaacat agaatctgaa ctaaaattag aaagagagcg atatcgtatt
     4621 gctttgcaaa atattacaga tatcatgttt gagtatgata ttgaaaacga tacccttata
     4681 aaatatcaac gtgtagaaat tgacaaaaaa attgaattag aaaattttga aacaaaaaat
     4741 tactccaaac tattagaatc tggtaaaatt attcaccttg atgatattgg aaaactacta
     4801 gaagtacttc atggaaatct tcgtgaaaca attgagataa gacaagtaaa ttcattaact
     4861 aaaaatgaat ggagatggat tcgtgttcaa tgttcagtta tatatgatag tgaccataac
     4921 cctatcaaaa caataggcgt tttaaaagac ataactgaag ataaatctaa attagaaagc
     4981 ttaattaatc aggctcaacg tgacccacta acacaattat ataatcaaag agtatcacaa
     5041 aatcttattg aagagtatct atgtagttct gattccaaaa ataatgatgc tctattagtt
     5101 attgatattg atgattttaa aactgtaaat gatacttttg ggcatttaga gggaaatgaa
     5161 gttttagttg ctgtatcaaa aatactatta cataacacac atgataaaga catagttgct
     5221 cgaattggtg gagatgaatt tacaatattt ataaaatcat taacaaagga tttaataata
     5281 aaaattacta atgatatttt aaatgatgca agtaaaataa aagtaaagga caatcataaa
     5341 ataacattaa gtattggtat tgccttcact gatgattcaa ctaaattata taaagattta
     5401 ttttctaaag ctgataaagc tctttatcta tcaaaagcag atggcaaaaa ttgttatagt
     5461 acatacgaat aataaagcta tttatacgac caagaatgaa cctttaaatt taatttcata
     5521 gtctaacaat caaagagttg aagctaatct tatagctagt caactagttc ctagaaaaaa
     5581 tttaaacaat atatttattg atactgctca tttttctaaa gagcaaattt atataaaaaa
     5641 ttaaactttt atgtacatac agatactaat gataaacagt tatcattagt atcttctatc
     5701 ttaaaacaaa atgataattt atctatataa aaaagtgctt tgttgacaga gttcactttt
     5761 ttatataggt acagaattta agtataaata catgttttat tctatacatt ttagttaatg
     5821 taaaatttct tgattgtact ctctaacttt tcaacattat actatttata taccacttag
     5881 ttaatataaa ccccttagct ggttctagtg ctttttctat gattttagtc atatttacat
     5941 accacttagt taatataaaa ccaatttaga tgatgtatat gtgcaaaagg aagaaataat
     6001 ttacatacca cttagttaat ataaaacggt cactacaact tatacttcca gtctaacgat
     6061 ttgaatttac ataccactta gttaatataa aacatatttt ggatttatta atataaacat
     6121 aattaaaaaa tttacatacc acttagttaa tataaaaccc caaaataaac tgggcatttt
     6181 caatacttac acatatgcaa ctctcttaaa tttgcagtga accatgagta gtgcaaatga
     6241 taaagcttat catataccct caacacctta tatttcaagc gttaagctct actttgtaac
     6301 aaatatcgct cactgcaaaa ctatttacat ttttattata tcataaatat attatttttg
     6361 aatatctata ccaatttgtg gtataataaa agcaagaaga actacaatct atttagacgt
     6421 agagtgaagt tcaaatacta atgtttattc tttttgaact tgatttttag ttcaaaacta
     6481 aagtcactcc tgcctgtgtg aactataccc gctgttttat acagttaaaa catgtaaaaa
     6541 tagttataaa gtactagtgt aactcattag tactcttttt attatattca tataattaat
     6601 atctatattt taaagtttac tatctaaaaa agagcacgtc aaataaaacc ctagatattt
     6661 aattttttta gagatactta aaataaatta tgctctctct gtacttaaat atttcctaaa
     6721 ttcaaatgga gacatagaat ttaatctatt ttgatatcta aaattattat agtagtatat
     6781 ataatcatct attgctttaa ctaattattc atatgtatca aatttcctta aatagtacat
     6841 ttctaccttt aaaattcccc aaaatccttc cataggagca ttgtcaaggc aacgaccaac
     6901 tcttgtataa tatatgtata tctaacacca ttaagaaata tatattttat aatatatatt
     6961 tcttcattta atgcacttag aaaagcaaag aaaatacaga ttagtacact ttttagagaa
     7021 aaataaaatt aatacatcta aaatattaaa aaatacttta gataatctaa agacacatct
     7081 caaagttttt aactaaatta taaaactaat tacaaatgct atgtaacgat aataaataaa
     7141 aaatttactt cgcttaagcg acgtgtcgtt gaaatatttc atgttgccaa ctggttcgta
     7201 agttgataag aaaagaacac taattattta gagttctttt cttagctaca agtggattat
     7261 aatactttta aatctgtgag aaaatcatat ataataatga tatgaacaag taaagaaaat
     7321 acaaaaatga caaaattata aataaaatat tataaaatca taaggtcata attgttatat
     7381 tgtagaaaca aagtaaagag agagggtgga gaataaatga atcaaaaaaa aataaagatt
     7441 agtattaaaa tggtaattat aggtatattt gctgtaatta ttgcttttgt attatccaga
     7501 ttattcgttg agtatattga tgaattatta aggtctaatt ggcaatatca gctatttgaa
     7561 agtgagagtt catatatagt atttgccaat tgtattatgt tctcgaatat attattagaa
     7621 atatttttaa tatatatttg tagaaaattt agaaaaatct aatatggtca acgtatttcg
     7681 aatcgaatac ttcatgatta tttagtctat tgtgctagtt aaagtttaat tcccatataa
     7741 agtaaattga ttttagtaaa acaaatcacc cctaagggtt agtttatgga taagtcatcc
     7801 aaatattaac tctttaattt ttgctataga ttcatctttg ctcataactt tacttataaa
     7861 aaatgaaata ttataagcta gaacttttat tctaattcta gtcataaatc ctagcataga
     7921 gttacttttt ttatattata aataaaacta tacaacaaag ataatattta gtaaaaataa
     7981 ctttcatttt aactaaactt aaaattcaat tactctctaa attgacgttt aggaattagt
     8041 tcaaaataaa aaagagtgta tatattgaaa ttactacatt tcaatatata cactcttttt
     8101 aaatttctca gttttccatg gaactttact ttatttattt ctgtattagt tgtatttttt
     8161 atgcattttt ctttaaaatc atattttctg attcaactct tatattataa aatttcttta
     8221 ctaaattatt ctctttttct atatcttcat atatattttt taatcgcctt ttacctaatc
     8281 ttttatctaa cattactaat gatttaacta atatattata tgattttatc gcatcttcta
     8341 ttgagatatt taaacatata tttactgctt cataaaaatc aaattcatta aaaaatccat
     8401 ttttatttac aatcttatat ccctttgcat ctctttctaa atactcttcc taaatactct
     8461 tcaaaacttt catcatctaa tctaaatcct atatcactat gaaaaatagg ttttgcattt
     8521 ggatatagtt ctattgtttt atcaaaagtt tcgaatacca agttattatt attcgatttt
     8581 ccaacagtcc actataaaca ataataagtt tgttgctcca aataatgtaa cacttgtaga
     8641 aagatgttac agatatataa aagatagaga atgtagtttt tctcctaata ctattagaaa
     8701 tagaaaaaat atgattaaaa atcaaattga agttttcttt aaagatatga aattaataga
     8761 tataactcct tctattttac agtcttatat aaataacata tacaatgagc acatgttaaa
     8821 ttcaacaaaa aaccaagtcg attttataaa atcagtattg aaagaatctt atagattaaa
     8881 agaaatatca gaaaatattt gtgattttgt tacaacccca atcaaaaaaa atagttcaac
     8941 ttctaagctt tatacaaaac aaaaagctca attattatta gaaaaatcaa aaaatattcc
     9001 tataggtata ccaatttttt tgatgctaac tcttggatta cgttttggtg aagctgtatc
     9061 acttatatgg tcagatgtag accttgataa aaaatctcac atgtaaatca aacattagtt
     9121 tatgtataca ataaaataat cttcaaaggc cctaaaaccc ctagattcaa aagaagatta
     9181 tttgttcctg atgaacttat aagtttgttt aaaggggaaa aattaaaaca aaataagtta
     9241 aaattacagg gtatattgaa aaatgaattt gatttgatat gcttaaataa aagattcaac
     9301 ccgtgagttc aaccaacttt tgttgttcat tttaaaaaac tattaagaga taataatcct
     9361 agagatataa aagtacatga attaatacat gcaaatgcga ctttgatatt actttcaggt
     9421 actaacataa aagctattta taaaatatta gtacatgcag atataaaaat agctatgaat
     9481 atatattcca tattctcact tattagatga aatgaataaa gaaacatctg aaaatataag
     9541 caaaatacta ttcaaataat gttcagtttt atgtcaatta aatgtcactc aaagtgcttt
     9601 ttttccattt gtcagttaaa tgtcacttaa agtacctttt tcctatttgt cagttaaatg
     9661 tcagtaatat ataaataaga tatatttata agacccttaa aatcactatt atttaataaa
     9721 atttataatt atatactatt tgctgttgac attggtatta taccatagtt tatcatttat
     9781 attagaataa aattattaat taatagtttc gtaattttat aatagattta cagggagtga
     9841 taataaatgg atacaaaaat atctataaac gaaaacatga gtctaggtaa aagatttttt
     9901 aaatacctag caccatctgt agttgcaatg tgggttttct cactatatac aatggttgat
     9961 ggaatatttg taagtaaagg agttggagaa ttagctttag ctgctgtcaa tatatcaatg
    10021 ccttttatta attttatatt tgcagtttct ctattatttt caactggtgc atctaccata
    10081 attgcaatct atctggggaa aaaagatatt aaatctgcta acgaagtctt ttcatttaac
    10141 ttagtatcaa taattatatt atcaataatt atattagcta taactttttt taatttagat
    10201 agattagcac tatttttagg agctacagaa tctacaattg gtatggttaa agattattta
    10261 ggaataataa tattttttaa cggattcttt atagtgtctt attctttaga agttataata
    10321 aaaactgatg gctttccaat attagctact gttggtgtaa taatatctgc tcttacaaac
    10381 atcatacttg attacttgtt tgtaattgaa tttggatggg gtgtaaaagg tgctggtatt
    10441 gcaactggtt tgtctcaagt cttttctact attttcttct taatacattt tttaagaaaa
    10501 aactctactt tgaatttttc aaaatttaga attgatttta agacacttag aaaaattgta
    10561 tttataggtt ttcctgattc aactactgaa ttaagttgtg gtatagttgt tttacttttt
    10621 aacttaagtc ttactaaata tattggagaa aatgctctta tttattatag tgtcataaat
    10681 tatataaata cattagtact tatgactatg atgggtataa ctcaaggtat gcaaccactt
    10741 actagctttt attatggtgc aggaaatata gataatgtaa aaaaattatt aaaaatgggg
    10801 ataaaagcca caataatagc atcagttgct gtatttgcaa tttgtatggc tttttcagga
    10861 ccaatagtct ctttatttat acatccagaa gaaacaatgc tattcaatga aggagttcgt
    10921 gtatttaaaa tattctctat atctttctta ttggtaggaa ttaatgtaat aatttctgga
    10981 ttctttgtat cagtagaaaa accatcaatt tctactgtta tatctcttgg tagagggctt
    11041 gtaatagttg ttttaagtct aatttcaatg atactaatat ttggtggaca aggaatatgg
    11101 atgactacta ttgtttctga gtttatatgt cttattttat cattagtttt tctaaaaaag
    11161 aatttttcta cattagactc taatctaaat aaggttgctt agatgataag agtgacaata
    11221 tatgaaaata tctaaataaa aaatacctat tatacaatct tgcaaatatt aaacctttgc
    11281 aaaaattagg attatataat aggtatttta tttatgtaat tattttattt ctaaatatcc
    11341 atagccatct tttattaaag ttccttttac ttcatattct acaggttttt taaatattgg
    11401 accatctacg acaaatgtat gatactctcc atgttctcca catgggtctg caccagcatt
    11461 ttttatcttc tccacaagtt ctctagttaa tttttttcct aaaaattcct ctcctaagtg
    11521 ctttaagttt acttttgtta caacactaca aaatccactg tctataaatt catatactaa
    11581 atcctctcta ctctcttgcc ataatggtaa atctactttc ataccaactg cttcacatct
    11641 atcagtatcc cattttctat gactttctat atctatatct ccatatgcac atatcgttgc
    11701 tcccatgttt ttagctttta ttaaagccct ctcaaagctc tcttcatatc cttctacgcc
    11761 acactcagca actaataaag gtaatcctat gttgctactt acttgcttaa gcatattata
    11821 ttctaaatta tgtgtccatg actttccatg ttcttcactt atagttgtca agagtgccac
    11881 aggcttatat ccttttttca acattcgatt taatgctaat atactatcct taccaccact
    11941 aaatgacatt acaaattttt catcagccaa ttttaacacc tctttcatct aactttgttt
    12001 tattaacata attataccaa atttttgagt tgcatagcaa attatattaa attgttaatt
    12061 cactataaag aatgtcccta atattaaaag tataacccct atgtatttgt ataaatgcat
    12121 tgtttcttgt cccaaaatta cgctatcaat aaaaaatcca actaaaactt gggatacaag
    12181 agttaatata agtgtatttg atactcctaa atttggaatt gcctttactg taaaatatat
    12241 tattagacct ccaaatactc ctcctaataa caacttataa ttaaaaccat ttatagatac
    12301 tagacacttt aagtcacctg taactattat acttgccaaa aaaaatattg ctcctacagt
    12361 taagcttata aaggtggcca ctaatgctgt tgtacttttt cctagctctc catttataaa
    12421 agcttcaaga gctgtagaac cacctgctaa taatgcaaat attattgccc ataattttgt
    12481 catggacaaa cctccttcta tataattcta ttaatagaag tttatgatac aacctattaa
    12541 ttaattacta agtatagttt aatttttata cactaggctt tatttggata tgaatttctg
    12601 ttataattgt tctatcgatt ttggaggtga ttttatgtac acaaatttta atatcgattt
    12661 taataacttt aataaaaaag aaaatgctat taaatttatg ttaatgggag tattactcat
    12721 tatattagga ttattatgcc ttacatttaa gacattaggt ataaaattaa tttcttggac
    12781 ttttggtatt gcacttttat tctttgcata tttaaattta aaaaatatta atgagttaaa
    12841 aagatatgct actaaagaag aaattaaacc ctctattaat atccaatggg ttctaataat
    12901 tgcatgtata ttactttttg tatttcctca aaaaatacaa agcatatttt cattattttt
    12961 aggattttat ttaatcttta atcaactagt agcacttgta aatagtaaga ataatcctta
    13021 ttctaaattt acaacttgga atatagttaa gattctattt ggtatatgcc ttatattatc
    13081 tccacttttt ttatctagat ttatagtatc gataatgtct tttttcataa tattatttgg
    13141 actagttcta tttttctctg gaaatacagc gagaaaatat taattatttt ctcgctgtat
    13201 ttttatatta cttaaaatag aatttgttta agttatctat ttgtggtaat atgttttttg
    13261 tacaagctca gcgtacaatt ttattagaaa taggtgattt tttggataaa tttaaatatg
    13321 cttttgataa taaaagatat catacttgga attactatct tagaaatact tttggagaaa
    13381 aagtttttaa ggtatctata aatgcaggat ttacttgccc aaacattgat ggaagtcttg
    13441 gttatggcgg atgtacctat tgtagcaaag aaggctcagg tgattttgct ggaaacccta
    13501 aagataatct tatcagtcaa ttttataata taaaagaaat gatgttaaaa aaatggcctc
    13561 atgcaaagta tattggctac tttcaagcct atacaaatac gtatgctcct cttgaagttt
    13621 taaaagaaaa atatgagact atattagaac ttgaagatgt cataggtctt tcaatatcca
    13681 caagacctga ctgtttgcca gatgatgttg tagaatactt atctgaacta aataaaagaa
    13741 ccaatttatg ggttgaactt ggacttcaaa caattcatga ttctacatct aaaattataa
    13801 atagaggtca tgattataaa acatttgttg aaggtgttga aaaactaaag tctaaaaata
    13861 taaaggttgt cgtacacatt ataaatggtc ttcctggtga agattataat atgatgatgg
    13921 aaacagcaaa ggcagttggt aaaatgggtg tagacggtat aaaaatccat ctattgcatg
    13981 ttataaaaga tactcctatg gaaaagatgt tacaaaatgg tatgttaact cttatggaac
    14041 aagatgaata tatcaatctt gtctgtgacc aattagaaat acttcctgaa actatgataa
    14101 tccatagact cactggtgat ggtaagaggg atgaactagt aggtcctata tggagcctaa
    14161 aaaaatggga aattttaaat caaattgatg atactttaaa ggctagaaat tcttatcagg
    14221 gctgtaagtt tgtttaatac aaaataataa ctatagaaat ggttatataa atatagtcct
    14281 ttctatagtt atttagtatt tacaaaaaca aaatattaat ttgtacattt atacaatata
    14341 taataaaaaa tagatagtct aaactgtatc tacttatatt ttatttgtac tgtccacttt
    14401 attctataaa atttataaat agttattttt taataccaaa tataatttgg tataattttt
    14461 gttggactct aaaatgtata ccaataaatc ctttttaagt atataattct aaatactttc
    14521 agttttttca atctgcttta acttgttgga cttataaaat attcttattt catcataaga
    14581 aagattaagt gctactactg cagatattaa catcaacatc actccaaata acttccctaa
    14641 ggaaaaactt tctcctaata tagtgcaacc aattattact gaaccaacta attctactga
    14701 tgccacaaca cctgcaactg acaactctac acctttagat atacctgctg cataaaaaat
    14761 atatgcaagt gcagctggaa caatgcctaa cattagcata caagataaaa catctaaatc
    14821 cttagcataa tttaagattt cccaaggtct tgaagaagga atcataaata tagctccaaa
    14881 taagaaactg tatactaata ttgttgaact tgaaaattcc tttaaagcat ttttactaat
    14941 agttggcata agtgcatatg ctattgctga taatacccca agtaaaagtc caaaagcgtt
    15001 taaaccttga aaatccaaac gtccaccagt cactgccata attgcaccaa taaaacaaag
    15061 aataagtgaa aataatttgc ttctagtaat attttcttta taacatattt ttgaaaatat
    15121 tgctaaaaac agtggtgatg tatatagtaa aactgctgca attgatacac ccgcaatgtc
    15181 aattgcttta aaataacata aattaaacat tgcctgacat ataataccta ttattactga
    15241 atatataatt ccttttttgc ttatctttaa gatttgtggt gtccttatag atgaatatac
    15301 gcctaaaact ataaatccaa aaaacaatct tgtaaatgct acttgttctg atgtcagtcc
    15361 atttcccatt aaaaactttc caaataatcc aagtgtagcc cataataacc ctgctattgc
    15421 tataaataca taccctttac ttttttctcc cattttaaat tcccttctat ttttatttag
    15481 tcaatttaca ctcttctttt taagcaaaaa ctatgccatc ttaaatcaat atatatcgac
    15541 tctaaaaccc tagtctttcc aataatacta ataaattttc aattttttta tatttatttt
    15601 tcacttactt taagttgatt tagacttatt ttaattgtaa aatgagttat atataactta
    15661 tttaaagtta aaatagactg aaacttatat ataaatatca aattttaagt atattaatca
    15721 attaaaccta ttttaatata tcattaaaaa tttaggagga aaatataaaa atgaatttag
    15781 atttggaatt ttatcaaaaa atattagaag cttcccatga tgaaatatgt gtttctgatg
    15841 ataaaggaat aataatatat tgtaataaag catttgaaga aaattatggt ctaaaaaaag
    15901 aagatatttt aggaaaaaat gtttcttttt tagaagactc tggatattca acaaaaagcc
    15961 ccataccaat tgtattaaaa acaaagacta aattttcact ggaacaagat actcaaacag
    16021 ggaaaaagct tatcataact gctaccccta tatttgatga aaatggaaac ttagaattta
    16081 ctgttgaaaa ttgtagagat ataactgaac ttaataatat aaaaaataaa cttgaagaca
    16141 caaaaaagca agtaaaaaaa tataaatctg aagtagaaac actatacaga actgcactta
    16201 gaattgagga tactgtaatt atggacggaa tagttatgag accaatcata aacacagtaa
    16261 atcatgtttc taaaacggat gtaagtgtac ttttattggg tgaatctgga acaggaaaaa
    16321 gctcacttgc tagatatata caccacaaca gcaatagatc taatggccca tttataacaa
    16381 taaattgtgc aactatatct ccacaacttc ttgaatctga actttttgga tatacttcag
    16441 gtgcttttac aggtgcaagt actaaaggta aagttgggct cgtagaatta gctaatggag
    16501 gaactctttt tttagatgaa ataggagata taccacaaaa tctacaggca aaatttttgc
    16561 aattaataca ggatagaact tttactccag ttgggagctt aaaaaataaa aaggtcgata
    16621 taagaattat atctgctaca aatgttgatt tagtttcaaa agtaaaagaa aaaaagttta
    16681 gagaagattt atactataga ttaaatgtta tagaaataaa attgcctcct cttagagaaa
    16741 gaagggataa tctagtggaa attataaaat attattttaa taggtactca agtgacttca
    16801 atctaaataa aactatttct aaagaagcta tggatgctat tgcaaattat agattcccag
    16861 gcaatataag agaattacaa aatataattc aaaaaatctt gcttacttgt acagataatc
    16921 atataacaat agatgactta ccaaacattc ttacaaaaaa tatacatatt accaataatg
    16981 gaaataaaac acatatatcc caaattaata aggttattat atctgactca aaatctacta
    17041 attataaaaa taaaaatttt gacactttaa ttaaagagta tgaaaaaaat ataattttgg
    17101 atgcttatga aaaatttggt agttcttata aagtagccaa acaccttgaa atctcacagt
    17161 ctaaagccaa taggttaatt agaaagtata ctaatactta attttaaatt tgataaataa
    17221 aaacttaaca ctatttacat attgtaaatt tggccattta ctgttattat gaatatggtt
    17281 gaaattattt aaataaatac tgttgactta gtttcatata tttaccatta aacttttatc
    17341 ataaatatca tatcataata atatatttaa taagtctaat aaactatacg aggtgtaaat
    17401 atgttaatga atacccattt tattatggca aaatcaatac ttgataatat agatgaaaat
    17461 aaaacattct ttataagcga aaaaaatttt atatatggca atataaagcc tgatgctttt
    17521 tctaaatata aattaaaaaa acattattta gatgagtcat ttaatatgat tgtttctaaa
    17581 ataaactatc tatgcagtct taatatagat agtctttcta aatacttttc agtaagtaga
    17641 cttagtcagg aactaggagt catatgtcat tttttatgtg attttttctg tgtagctcac
    17701 agtgaacgtt gggagtttaa gcatagctta aataaacatg ttacttatga aagagaactt
    17761 ggagcatttg caaaagatgt tgatttatct aaaattaaat gtggtactat aaatagtagt
    17821 tttgagaagt tttttactaa actttatagc gattacaaaa agaaaactga ttatatgaat
    17881 gatttaaaat tttcagctta tacttgtaat agtgtcataa attatatact tgactctatt
    17941 ttatctaata caataaaatc atatcatata gcaaattgcg gttaacttaa gaatttttaa
    18001 acttatataa acttataatt gaatataatt aaaatgactg ctctatagaa tataatttta
    18061 tacttctcta ggacagtcat tttttatact aactatttat ctccattata acatctatgg
    18121 cactttttac actatctact acataatttg cactttgctt tacatcttcc cttgccttag
    18181 acattgcaaa actatattta aatccttcta acatgcaaat atcatttgga gaatccccaa
    18241 tagtagcaac ttcatctgga cttacattta acgtttttat tacatgctct atacttcctc
    18301 tttttgacac acttttagga actatattta aagtatatgt tccagaaaaa tatatttcta
    18361 agacttcact aaactcactt tttagataaa gttctattct ggataactct tccaaatttt
    18421 cagaacatac gcctatattt cctataagat tatcaaaact acttcttttt tcaaagtctg
    18481 ggtcaactat aaagtcacta gaataatgtc taaaagcagt ggtatcacta cccacaatta
    18541 catcaccctt atatttaaaa taaagttgtg catcacttga ctcaaatcta tcaatgactt
    18601 tttttactaa attatcatct atcgttcttt taaaaattac attataatct ttatcatata
    18661 taaatgaacc attttcacat acatagtatc cattcatatc taaactatct ttgataatat
    18721 tatgtgcttg tttaaaaatt ctacctgtag caacattaaa ctgtactccc tttttttcta
    18781 tttcttcaat tgctactata tcttcttttg ttatggttcc attttcatat agagttccat
    18841 ctaaatcaca aaatatatgt tttatcataa attaaaagcc tccaaaaaca attttatatt
    18901 ttactaatac tttaatcaaa ataacttaaa gcttttctaa ttgtattctc aactcattaa
    18961 gcaaatctct agtagctctt aatcttatct ttcttctatc cccattaaat atatttttct
    19021 ttactattgt ttttccattt atatatattg cagtataaac cagtcccaca ggcttctctt
    19081 tggttcctcc accaggtcca gctactccag ttgtagatat acctatatta gctttaagtc
    19141 ctttagcaac gccctcagcc atttctatag ctgtttgctc acttactgct ccaaactctt
    19201 ccaaagtttc tctttttact cctaatcttt tcattttaga atcattagaa tatgttacac
    19261 aaccttcaag aaatacagag gatatacctg gatagtttat aagagatgaa gaaaccaaac
    19321 ctccagtaca agattcagcc actgctattg ttagattttt ttctacaagt agcttagaaa
    19381 cagcatcttc taaagcagtc tccccttcag atatggaaat atctccttca gtatatacat
    19441 atttaccaac tctacttttt attttttctt ctactggttt tattaattta aaagcttctc
    19501 tttcattttc agcctttgca gttattctta ttgtaacttc taattctttt gcatataaag
    19561 caactgttgg attagtctgc tcattaatta tatcgagaat ttctaattct agatttgact
    19621 cacctattcc atataatctt aaagtcttag atactagcat ttcatttgtg aattgttgta
    19681 agtaaggttt gacactctca ttaaacatag ctttcatttc tcttggaggt ccaggcaata
    19741 ctattataaa tttaccatct ttttttaaaa ttgcccctgg agctgtacca ttattatttt
    19801 ttagtactat agcatctttt ggaaagtaca cttgtttcat attattttcg gccatttttt
    19861 tccctgtttt aacaaagaaa gattccaaaa cctctagtga aggtttatgt agttctaatt
    19921 tctgaccaaa gtattctgca gcagtttctt ttgtcatatc atcaccagtt ggcccaagac
    19981 cacctgtagt aattacaaaa tcacttctct ttaagctttc atcaaaacat tctaaaagtc
    20041 tttgtttgtt atctccaaca gtactctgat ggtatacttc tattcccaat gatgcaagtt
    20101 ctttagctaa aaattgagaa tttgtattta ctatatctcc caataatatt tctgttccta
    20161 cacttattat ttcagctttc aaaatttatc actccttgat ttatagccat taagactagt
    20221 cttaagttca taacaataat tttagcaaaa ataataacat aaataaagtt aaaaaatcat
    20281 ttaaacatat ctttaaacta gattattatt ctaaaaccac acataatata aacttcgtat
    20341 atagtggtac tttcatcctc aactgttaat tcatataatt aagtatgtaa ataaaaagtt
    20401 tactttaaaa taataaaaat taaaatagga gtgtataata tgaaaatagc agttataatg
    20461 ggtggaatat catcagagag agaagtttct ttaaattcag gaaaagagat atataataac
    20521 cttgataaaa ataaatatga agttgtaaaa gtaataatag atgataaaaa agatatattt
    20581 acaaagatac cagaagatat agattttgca atacttgctt tacatggaaa atttggtgaa
    20641 gatggatgta tacaatcaat acttgagact atggatatac catactctgg atgtggacct
    20701 ctttgcagtg ggatgtgtat ggataaaaat ataactaaaa aaatgcttag agattcaaac
    20761 ctacctactg ctccatgggt tttagtaaaa tcagttgatg aaatagacta tgatgaaata
    20821 gataatatag gttatccagt atttataaaa ccaaactcag gaggttcaag tgtagccaca
    20881 ttctttattc attctaagga tgaagttgaa gaagcagtta gaaaaggtct ggaagttgat
    20941 gaatttgtaa tgattgaaaa atatatacca ggtggagaat atacttcatt catattaaat
    21001 ggagaagtgt tccctacaat atctataaaa tctgattcag gattctttga ttatgaagct
    21061 aagtactcag ttgaaaaagg tgcaaaggaa gaagttgttt acttagatga agaacttcaa
    21121 aaaagagtaa acgaaatttc tgagacttgt tggaaaattt ttaattgcaa agcatatgta
    21181 agagttgata tgattataag tgaaggtatt ccatatgttc ttgaactaaa tactcttcct
    21241 ggaatgactc aaactagttt aattcctaga agtgctgctg ctagaggtat taagtacagt
    21301 gaactattag ataaacttat agaatactct ttaaattaga tgaaataatt tgaggtggta
    21361 atttgatatt ttcaaatcta aaactaaatg ataatgaacc aatttatata caacttaaaa
    21421 attatataag tgatatgata tcaaaaggac taattccaga caatagtaag ctcccttcta
    21481 caagggagct tagtcagctt ttacaagtta gccgaaattc tgtagtttta acttatgaag
    21541 aattaaaatc agaaggatta atctactcta tttcaggaaa aggtacattt gttaaatcaa
    21601 agaataagtc ttcaaatact acatggtcat taaactggga ttgtttagag aatacatact
    21661 ctaaaaaagc caatgaattg gacattataa aaagtgaaat tccttggagc tctgacctga
    21721 tttcctttaa aagtatttct ccagatggag atttattcga catagaagaa ttaaaaaaat
    21781 cctttttaaa tagaatttca ctagaaggac ataaattact caactatgga tatgcacaag
    21841 gttataagcc tcttattgac tatttactag aatatatgac aaataagggt gctgatataa
    21901 gtaataaaga tatactaata acaaatggat tcacagaagg ctttgatatt attatgtcat
    21961 cttttaccca agaaaaagac tacataatat gtgaaaatcc tactcataat actgctataa
    22021 aaattatgaa atctcataac ctcaatatct taggtgtaga tataaatgaa gatggtttgg
    22081 acttcaatat gctagaagac aatttagtta agtataaaaa taaaataaag tttgcataca
    22141 ttacaccctc ttatcacaat cctacaggaa ttgtaatgac tcctgaaaat aggtacaaat
    22201 tctataatct tatgaaaaaa tacaatatag caattataga agatggattt aatgaagaat
    22261 tactctacaa tagttctcat atatttccta tctgttccct agataatatg aataatgggg
    22321 tcgtatatat tggtagtttt tcaaaaattt tatttcctgg aatgagaatt ggatggatat
    22381 ttgcagataa aaaagtaatc aataagctag aaagtgtaaa aaggtgcaga aacatacatg
    22441 tatccttttt ggaccaagga attttatttg attatttaag taatggaggt tttgaaaaat
    22501 acattaaaaa aatacgtaaa ttctatgggg acaaatttaa ctttgcatat aagtgtataa
    22561 aaaaatatat aaaaacagaa tatatcttgg gtgatggtgg tttgcatata tttataaaac
    22621 taaaaaatat agatactaga gttttattag aaaaatgtta tgaaaaaaat gttatattta
    22681 tgcctggaga tttatttttt acagataact ctggttttga tactttaaga ctcggatttt
    22741 ctaggttgtc ttttgaagac attgaaattg gaataaaaat aattggagaa actataaatg
    22801 aaatgttcta ggttaactaa atattgttag cctagtttat ttttatgagg tataatatat
    22861 atagtttata tgaatctaat actgggggat aatatgagta aaaagtcaaa acgaagaaaa
    22921 attaataaat taaaattaac gattgtaata actgtattat ttcttgcttt attatctata
    22981 tatgagatac tgttctctaa tcccaacaaa aaaggtaata taaagagtca agaaactatg
    23041 caaaataaaa ataatacaac agatgattct aaaaataatc aaagctctac caaaaagcag
    23101 gaagataata atatcaagcc tactttttca tattcttcaa taccagataa tataaaaaat
    23161 aaaatgattg gtaaatctat gcctactgat gaacctataa gctttgatag tctatcttat
    23221 ttaaaactta catattatgg atttgatgaa aaaactcatc aaggagaaat gatagtaaac
    23281 agtgaactag ctccagaagt agtggatatt tttaaggaat tatacgaaaa aaaatatcca
    23341 attgaaaaaa ttaagttaat agatgactat gatgctgtag atgaaaaatc tatgtctgat
    23401 aataatacct catcattttg ttatagaact atagctggta caaatgtagt ttcaaatcat
    23461 ggtaaaggac gtgctataga tataaaccca ttacagaatc ctcaagtttc tggaaatgat
    23521 gttacaccta aagtaagtac agtttatgct gataggtcta gcacaaaatt tggaatgata
    23581 aaaaaaggtg atgattgtta taatgctttt gtaagcagag gttggagttg gggtggctat
    23641 tggaaaaacc cagattatca acattttgaa aaataataga ttagaaataa aggtgaatta
    23701 tatgaattta atgacattgg aaaatataag taaaagctat tctgaaaaaa aattactaga
    23761 aaatatatct cttggaataa atgaagggga aaaaatagga cttattggtg taaatggtac
    23821 tggtaaatct accttactca aaattattgc aggagttgaa gaaagtgaga ctggtaatat
    23881 aacaaaaact aatggtatta ggatagaata tctacctcaa aatccaactt acaatgaaaa
    23941 ttcaactgta cttgaacaag tatttaatgg aacttctgaa gaattaaagc tacttggtga
    24001 atatcaagaa atcctagaaa aacttaattc aaactttaca gaggaattaa ataaaaaatt
    24061 attatcagta cacgaaaaaa tagatgcctt aaatctttgg gatttagaaa gtgaagctaa
    24121 gtcagtactt acaaagcttg gtataaatga ctttaatcaa aaaatagcag aactttctgg
    24181 tgggcaaaga aagagagtct ctctggcatc agcccttatt acaccttgtg agtttttgat
    24241 actagatgag cctacaaacc atctagacaa tgatactata gattggcttg aggaatatct
    24301 taattccaga aaaggctcat tgcttatgat aactcatgat agatactttt tagaccgtgt
    24361 tacaaataga attattgaac tggacaaagg tagattattc agttatgatg ggaattattc
    24421 aatatttttg gaaaagaaaa tggaaagact ttcgctagaa gcaagtattg aagataaaag
    24481 acaaaattta ataagaacag agcttgcgtg ggtaagacga ggagctcagg ctcgtagcac
    24541 taaacaaaaa gctcgtttac aaagatttga tgaacttata aatagagatt cttttaaacc
    24601 tgatgaaaat cttgatatat ctgttgcatc aagtagactt ggaaataaaa taatagaaat
    24661 acacaatata tctaaatcat ttgaagaaaa tactgttata gataatttag aatacacttt
    24721 aactcgtaca gatagaattg gtataatagg caaaaatggt atgggtaaat ctacccttat
    24781 aaatatactt aatggagaaa tagagcctga tagtggatat atttcaattg gagaaacggt
    24841 taaaataggt tgtttttctc aagacgactc tcatatgaat attgatatga gggctataga
    24901 ctatgtaaaa gaagctagtg actatataga aacttcagat ggtactagga ttacagcttc
    24961 tcaaatgtgt gaaagattcc tttttaatgg tactatgcaa tatactttga taggtaaatt
    25021 atctggtggt gaaagaagaa gactacatct tcttaaaatc cttatgacag ctcctaatgt
    25081 gcttctttta gatgaaccta caaatgattt agatattgaa acgcttaaaa tattagaaga
    25141 atacctagac gaatttaaag gtgtagtagt tacagtatca catgatagat atttcttaga
    25201 tagaatttgt aataaaatat ttgcatatga aggtaatgga aaaattcata tctatacagg
    25261 taattacagt gattatctta tttatagaga gattcaagga attgaatttg aagaatctaa
    25321 aagggaatca gttaaaaaag atgactctac taccccaaaa aaagaaaaac ctaaaaatga
    25381 taaaaagctt aagttctcat ataatgaaca aagggagttt gaaaatattg actctgatat
    25441 agaaaaactc gaatctaaaa ttgcaacact tgatgaaagt actgcaaaat tttcaactga
    25501 ttttactaaa ctccaagaaa ttttagatga gaaatctaaa ctagaaaaag aacttgaata
    25561 caaatatgaa agatgggaat atttaaataa tctagctgat gaaatagcta ataataagta
    25621 atattaaaat aatcttaagt ttaataagtt ttgctttaaa tctgtaattt ataaatattt
    25681 taaaggaagt gtctcaaaat gaacttttta gttttatgag acactctttt ttatgagaaa
    25741 tcaaatatat tttcatcatt tcaacaatac aaaagaggct tatctctatt ttgagacagc
    25801 ctctttcata attaccttct aatttatatg ctctaatata tctataataa ttcttattat
    25861 atctatatat ccagtctttc aatatagtga caattaactt caatatgatt taaaaatact
    25921 aacaaccttt cataaagtgg atgagattct tctccatatt tagcttctag gttcttgcct
    25981 atttctctaa cagtcctttg accatcaatt tgtaaaaaaa caaaactgga atattcatct
    26041 agttctattt ttttgtattt aggtattcta gcttttaact ttctaaaaaa cttttgaatt
    26101 ttatggtcct gtttttcaag tatagtaaca acacgatttt cagctacttc atattcaagt
    26161 ccatcagtaa ttttaaatac aatatctaaa acatcattac tcttgctcat tattttttac
    26221 tttagataaa acaataggta atgctgtaag cacaactaaa actactaata aagcaattgc
    26281 cattgaattt gttgcagcaa atccacttgg tacctttgga gttacaactc cagttacttg
    26341 taatattata cctattaaac caatgataga accaccagca acaagaccag aagataaact
    26401 tataccatta gaaactttaa cttctttttc tttttcagtt ttagatacta attcaacaaa
    26461 taaacgaatt aatgctccaa ctaatattat agaagtagtt gcaattggta aatagaatcc
    26521 tatagctata gtcattattg gtaaatttaa tgcatataga actattgcca taaatactcc
    26581 aacaataatc ataacccaag gtaaactacc tgacataata ccagaagtta atgttgacat
    26641 taagtttgct tgtggtaatg caaattgtac attatcacca gttgctctaa gttggtcaga
    26701 aagtaataaa attactccta caacaactat aacaccaact atacttgcaa ttgtaaagta
    26761 acgttgcatt tcgtttttgc taccaccaat aatataagtt actttttgag attgagtata
    26821 acctccagct atagcaatag caacaactat aaatgaacca aataaaagta atgatttatt
    26881 agcttctaaa tcagtccatc ccattataac aaacactaat gttacaataa ctagagaagc
    26941 tatagtcata ccagaaactg gaagatttga tgttccgatt gttcctgtta aacgaccagc
    27001 tactatgaca aataataaag ataataaaag agatatgata gctccaataa ttgccataac
    27061 aatgttacca gaaattaaga atgctgctaa aaatccaata actactccac ctaataaaag
    27121 tatcatttgt atagatgaac cttcttctcc ttctccagca cttgatttag ctttaagtgt
    27181 ttcttttata gaagcgatta tagttggtat aagttttatt gcaccaataa tacctccaca
    27241 aagcatcata ccagcaccta tatattttac ataactacta gatattgctc caacatccat
    27301 ttggttaaga ggcattgcag gattattcca taccatagct ccatctttag ccatatctgt
    27361 aaagtatcct attaaaggtg ctataccaaa gtttgataaa atacttcctg caaacattgt
    27421 taaagaaact tcaagcccta ctataaatcc aattcctaaa agtagaggat ttacttcaat
    27481 atcaaatttc catttgtaga atttgcttcc tacaagactc attacattgt ttgctacatt
    27541 taagaatgaa ccagttaata cagtaataaa tccacttatt acaaatccaa ttcccatgta
    27601 cttaattgaa tctccaccag cctctgaagc aacaagtgtc tcagatatag ccattgattc
    27661 tgggtacata agtttaccat gttcttcaac tattagatag ttgtgaacta tagcagcaat
    27721 ccctatacca aataaaactc caccaactcc aacagctaag ccttctaaga atgtaatttg
    27781 gcttccaatt aatataactg ctggtaatac gaaaataaat ccacttgcaa cagattctcc
    27841 accacttgac ataccttgga ttaagttttt accaagaata ccctttgaac gagcaaatgc
    27901 tccaacaaaa gcagaaccta ttatagctcc tggaatacct gcggcaactg taagaccggc
    27961 tttcattcca gagtaagttg tagatgcggc aaaaatggca gctaaaataa taccgataat
    28021 cagtacagct acatttccac cggttctgga cttatctgtg atatatggaa cgtaatcttt
    28081 tccactaacc tcaccataag cacccttagg taattttttg ttcataaaat tttcacccct
    28141 tttcaatttg tatatattat aacatatata catataaaac ttaacttttt attattttac
    28201 aaatagcgag tcaaaactac taaaatttaa ccctatatta ttaatttcta cttttagata
    28261 tttttatgct aattttcttt ttatttttca attctactaa aaactattaa gatataaaat
    28321 aaaaaaattt tttaatgtaa aattaatttt gtaaaaaaaa tgctttaaaa cacggaaaag
    28381 tataaaaaat acaataatca ttcttataaa taaattttca ccatagtaaa tatatacaga
    28441 aaattcttgt ttttatgcaa attgattatt ttataaaaat aagtgtcata aagaaatgtc
    28501 tgaaatcact ttatgacacc tatcataata aaaaaattat tctggtaatg ctcttttatt
    28561 tacttttccg attggtgtaa ctggtatctt atctatcctc attattattg ttggaatcat
    28621 atatggaggt agatgctcat ttaaatattc tctaatagtt ctttcattta tcttaccact
    28681 atcttcctca tcaattacat aatatgcaca tatataaata tctccatcat catttgttct
    28741 cgatatacaa acaacacttt taatttctgt aatattattt attatatttt caatctcata
    28801 tagctctatc ctaaactcat caatttttac ttgattgtcc atccttccaa tataatctaa
    28861 atttccatca tctaaccatc ttactaaatc accagttcta tacattaact tattatgttc
    28921 acaagttttg taaggattct ctacaaatac ttgctctgtt agcccttttt tatttaaata
    28981 tcctcttgat atttgaatgc ctgatagaca tagctctcct ggtgctccaa ttggacatag
    29041 tttgttcttt ttatctaata catatgcata agtattaaat ataggttttc ctattggtat
    29101 ttttccatat tctctgtcca catgaaaaga agtcgataca acagtaaatt cggttggtcc
    29161 atactcatta tatagttcat aattacgctt tctatatcct tttaatcttt ctcctccagt
    29221 ctgtacaact ctaagtgaat tattattgca attttgtata aataaccttg caaatgctgt
    29281 tggcaatgct agtatagtta tgtcattttc ctcacagtat tcatttactg tatattcatc
    29341 aaatttagct tcttcaggca taatatctat tgatgcacct acaagcaaat aagggaatag
    29401 ttgtttcatt acagcatcaa aactgaaact taagtatata ccacatatat cattttctgt
    29461 agcgcttata gattttacgc tataataaca catatttact aaactcttat gttctatagc
    29521 tatggtcttt ggcctaccag ttgaccctga agtagatatc gtatatgcac aatttgatga
    29581 tgttattttt tcagttaatt catatccaaa cttaaacatt tcttcatcat ttatatcgag
    29641 tactatggta ttctcattta caaccttact tttgagttca tctgtagtta tcactacttt
    29701 cgcattacta tcttcaagaa ggtaattcaa tctttcttct ggattacttg tgtctattgg
    29761 aaaaaatgct ccccctgatt tcataatccc tattgctgta ataattatgt taatatctct
    29821 tggtaacatt acagctacta tgtcttcact ttccactcct atatgattta aataacctgc
    29881 aagtttatca gttacttcat ccaattcttt atatgttaac tttctatttt catccctagc
    29941 agctatatta ctaggtgtta ccttaacttg ctccctaaat aaatcaacat aacttttatc
    30001 atagggtact tcatattgat tattattaaa gtcttccaat aatacttttt cttcttcctt
    30061 acatacaaat tctaaatctt ctattaaaat atcattatct tctattattt gctctattat
    30121 ataatcaaat tgatttaaaa ttcttctaat agtttctctt ttatatatag atggtttata
    30181 ctttattttt attttaagtg ccctcttagt atatactatt acagataaat catatccttt
    30241 tttttctatg tcataatcat atgataaatc aaaactttta gctataaata ttgtgtttat
    30301 aagcttagta tttagatgat ttttattctc tatatctgat aacaaatagt atccatactc
    30361 taaagacctg ctccactgcc tttttagctt ccttacaaca tctataaatt tttcactttg
    30421 tctaactctt actcttattg gaattatatt cattgtttta ccaaaaacta catcatcttc
    30481 atatatatac ttttgaagta taaggccata tatagtttct atgatagagt ctatgctaat
    30541 attgttcact ttagaatatt gaattaacct ttcatgtttc tcaatattca tcttaaaaac
    30601 ctcatctact acttcatcag aacaatcttt ataaaaaaaa tcatttggaa tttttgctat
    30661 attcgtataa tcatctaaca aatccatcca ataattcata gctcgttcta aattaacttc
    30721 atacatatca aaattccccc ttactactaa gtctatagaa aaaattcttt tggaatttta
    30781 ttttcacaat atataaatat attaataata catatgcaag ctctaaaaac atgagcttgc
    30841 ataaaattac acttattatg actactaaat tcgtaatatt tacaatgttt aaaatatatt
    30901 ataacacata tatgatttta tttttctaca tttatataat atataaatta caaata
//
LOCUS       DAMKNB010000039        30887 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.041, whole genome shotgun sequence.
ACCESSION   DAMKNB010000039 DAMKNB010000000
VERSION     DAMKNB010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 30887)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30887)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30887
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.041"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            complement(61..1737)
                     /gene="bclA2"
                     /locus_tag="PC494_002052"
     CDS             complement(61..1737)
                     /gene="bclA2"
                     /locus_tag="PC494_002052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-like exosporium glycoprotein BclA2"
                     /protein_id="HDF3912552.1"
                     /translation="MSDISGPSLYQDVGPTGPTGATGPTGPTGPRGATGATGANGITG
                     PTGNTGATGANGITGPTGNMGATGPNGTTGSTGPTGNTGATGANGITGPTGNTGATGA
                     NGITGPTGNKGATGANGITGSTGPTGNTGATGANGITGPTGNTGATGATGPTGLTGAT
                     GATGANGITGPTGNTGATGANGVTGATGPTGNTGATGPTGSIGATGATGTTGATGPIG
                     ATGPTGADGEVGPTGAVGATGPDGLVGPTGPTGPTGATGANGLVGPTGAVGATGANGL
                     VGPTGATGATGVAGAIGPTGAVGATGPTGADGAVGPTGATGATGANGATGPTGAVGAT
                     GANGVAGPIGPTGPTGANGVAGATGATGATGANGATGPTGAVGATGANGVAGAIGPTG
                     PTGANGATGATGATGATGANGATGPTGATGATGVLATNNAQFTVSSSSLVNNTLVTFN
                     SSFINGTNITFPTSSTINLAVGGIYNVSFGIRATLSLAGFMSITTNFNGVAQNNFIAK
                     AVNTLTSSDVSVSLSFLVDARAAAVTLSFTFGSGTTGTSAAGYVSVYRIQ"
     gene            complement(2115..2654)
                     /gene="hpt"
                     /locus_tag="PC494_002053"
     CDS             complement(2115..2654)
                     /gene="hpt"
                     /locus_tag="PC494_002053"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HDF3912553.1"
                     /translation="MDIETKKWEVLYSEEKIKDKLRELGAIIEKDYKDKNLMVVSLLK
                     GSFIFCADLVRNINLPLRVNFMTTSSYGNNEESTGRVKVVSDVTTDIAGYDVLVVDDI
                     TDSALTMDFVLKHLKAKNPASLKCCVLLDKPSRRKVDLVPDYCGFEIEDKFVVGYGFD
                     FGDYYRNVPYIFNVTDEDR"
     gene            complement(2982..4289)
                     /locus_tag="PC494_002054"
     CDS             complement(2982..4289)
                     /locus_tag="PC494_002054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine dehydratase subunit alpha family protein"
                     /protein_id="HDF3912554.1"
                     /translation="MRDIRKELVEMLKAEVKPAVGCTEPVALALACAKAKELLGEEIV
                     ENRMLVSPSIYKNGMCVGIPGTERLGLKIAAALGIVGGHSENGLSVLETLTKEEVKIA
                     EDYMDNTPLSITPADTREKVFIEVVLKGKNHIAKVRIRTKHDNFTFLEKDGEVLLDNE
                     PKVSASNDAAEKAESLMDTVTIQELIKNVEGIDFKDIEFLLDGVKMNEEMAEYGLKQK
                     TGIGVGYGIKKSIEEGLLGNDVINYAMMLTAGASDARMAGVKMPVMSSNGSGNHGLTA
                     ILPIVAYNKKFPQSDERLAKALAISHLVTGYIKNYTGRLSAVCGCGVAASTGATAGIS
                     WLMNGTEKQIEGAIENMIADLSGMICDGAKAGCALKLSSAASAAIQSAIIAKQDCFVP
                     PLNGIVGSSVEQSIQNLGRVSDKGMSITDEIILNVMNDMNKVD"
     gene            complement(4714..6489)
                     /locus_tag="PC494_002055"
     CDS             complement(4714..6489)
                     /locus_tag="PC494_002055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDF3912555.1"
                     /translation="MMIMIGLEYIKSDIQNIAEAIVSVLNIDVTIVNKELFRIAGTGV
                     YIDKIGEKVDKYTAFKKSLTEQITILIDDPKSSDICRECYKSGACVEFAEVCCPIICD
                     GDSHGVIGLIAFTKEQAQIIENNKSGLINFLGKMADLISNKLKAQIKTYELELEKKKL
                     ETLLNNMDKAVVSIDVDGKIDKYNSKFKELFNIKDSITGKNIFVELDFIKKPSINNFK
                     KDKSCSFFYKRYGYDSKGIYNINKIVLKNELKGYVIDFIDKRDAIKNYNKMNKDYRIK
                     LENIIGESVAIRNSKKEALIASKSTSTVLITGESGTGKELFARAIHNHSNRVDNPFIA
                     VNCAAIPDNLLESELFGYEEGAFTGAKKGGKLGMFEVAHKGSIFLDEIGDMSLHLQSK
                     LLRVLQEKELNKIGSKSNVSIDVRIIAATNKDLEKMVQNGTFREDLYYRLNVIPIKLP
                     SLRERKEDIPLIIKHMVKEYSKKLDKNVIDIDSRVVDAMMEYKWPGNIRELQNIIEYS
                     VNMSSSSIITMNVIPQKIKNTSVEELEVKSDRIIPLDELEKIEIIKALNKYKDYKKDK
                     ELTAKALGISRATLYRKIEKYNIIS"
     gene            complement(6486..6623)
                     /locus_tag="PC494_002056"
     CDS             complement(6486..6623)
                     /locus_tag="PC494_002056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3912556.1"
                     /translation="MEINYELIIIVMLFVILMSIQFTLNKIYLILKEIRQILMLKKNK
                     E"
     gene            complement(6701..7270)
                     /locus_tag="PC494_002057"
     CDS             complement(6701..7270)
                     /locus_tag="PC494_002057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HDF3912557.1"
                     /translation="MKSILCQINKQPVKAKYTSDELECFLDTIEYNVGDKILLVGHIG
                     NLGKRLRGLGTSVTILENSNYEDVCYSLVYNENCNVVKGKLEFLPFDDNQFNKIIIVD
                     QFNVITDCEKASSEIQRVLKGNGEVILEDLNLKNLKVKLNYLKHKFCGSVAKIHYPHE
                     VFNIFSRLNFDGMIKESNKLKYIYVGKRR"
     gene            complement(7454..8089)
                     /locus_tag="PC494_002058"
     CDS             complement(7454..8089)
                     /locus_tag="PC494_002058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HDF3912558.1"
                     /translation="MIAVKDENNVVNLRGELDNKLEFSHEIFGEKFYNMKIKINRLSD
                     SFDILPMTVSERLLQDIDLDKQNLVNVVGQLRSYNKTLNNKNRLVLTVFVREIKSIDE
                     ENKDPNSIFLDGYVCKEPVYRKTPLGREITDLLVAINRPYNKSDYIPSIVWGRNAKFA
                     KNLKVGDRIQLWGRVQSREYEKKIDENNVVKKMAYEVSISKIKKLDENNNE"
     gene            complement(8757..9638)
                     /locus_tag="PC494_002059"
     CDS             complement(8757..9638)
                     /locus_tag="PC494_002059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TSUP family transporter"
                     /protein_id="HDF3912559.1"
                     /translation="MVAILKALYVVFAAIFAVVFGKDVAKANKEGKLEEQSTPKVAVT
                     GFITDFFDTLGIGSFAPTIAMSKALKLNIPDKKMPGTLNVAHTIPVVTEAFIFTSIIP
                     VDGVTLVSMVVAAAVGSYIGAGIIAKMDERKIQLVMGVTLALTAILMLLGHPWINVLP
                     GGGNELGLTGAKLVIGVIGNFILGALMTAGIGLYAPGMAMVYFLGMSAKVAFPIVMGS
                     CALLMPVASMKFIKEDAYTKKASVIIAICGLIGVFVAAYIVKTLPMDILKALVIVVIA
                     YTSATMIMAANKNKKTA"
     gene            complement(9758..10765)
                     /locus_tag="PC494_002060"
     CDS             complement(9758..10765)
                     /locus_tag="PC494_002060"
                     /EC_number="5.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline racemase"
                     /protein_id="HDF3912560.1"
                     /translation="MKFSRSIQAIDSHTAGEATRIVVGGIPNIKGNSMPEKKEYLEEN
                     LDYLRTAIMLEPRGHNDMFGSVMTQPCCPDADFGIIFMDGGGYLNMCGHGTIGAMTAA
                     IETGVVPAVEPVTHVVMEAPAGIIRGDVTVVDGKAKEVSFLNVPAFLYKEGVEVDLPG
                     VGTVKFDISFGGSFFAIIHASQLGLKIEPQNAGKLTELAMKLRDIINEKIEIQHPTLA
                     HIKTVDLVEIYDEPTHPEATYKNVVIFGQGQVDRSPCGTGTSAKLATLHAKGELKVGE
                     KFVYESILGTLFKGEIVEETKVADFNAVVPKITGSAYITGFNHFVIDEEDPLKHGFIL
                     K"
     gene            complement(10785..11267)
                     /locus_tag="PC494_002061"
     CDS             complement(10785..11267)
                     /locus_tag="PC494_002061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline reductase"
                     /protein_id="HDF3912561.1"
                     /translation="MSFVGISTSMKNTSLHIFRDPLLDLIDNDSDIDLLGVVVVGTSE
                     HNEWKTFLATRLGRWIESLRPDGVIITLDMAGNQHIDFTNAIAEFVKSDIPTVGLTIM
                     GADGLVITNPYLDKATIIDYKKTTGYIETEVVGDNHMDEVDVKKALAFLKLKMRKDAK
                     "
     gene            complement(11285..11752)
                     /locus_tag="PC494_002062"
     CDS             complement(11285..11752)
                     /locus_tag="PC494_002062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline reductase"
                     /protein_id="HDF3912562.1"
                     /translation="MGIGPSTKETSLHHFRDPLLDIVESDKDVDLLGVIVVGTPDGNE
                     NKTFVGQRTAAWLEAMRVDGAIVSSDGWGNSHVDYANTFEEIGKRDIPVVGVTFNGTQ
                     AKFVVSNQYMDTIVDMNKSKEGIETEVVGENNTNEIDAKKALAFLKLKMRKHG"
     gene            complement(11767..12525)
                     /gene="prdD"
                     /locus_tag="PC494_002063"
     CDS             complement(11767..12525)
                     /gene="prdD"
                     /locus_tag="PC494_002063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline reductase cluster protein PrdD"
                     /protein_id="HDF3912563.1"
                     /translation="MEEKIMRRLVIKPFHMNEVNFGSKTSIKKDVLTIDLSSIDEIKE
                     REELITDIKVDIIKPGDYDREINTIMDIIPISTKVLGRLGEGITHTLTGVYVMLTGAD
                     EDGNQMHEFGSSEGILKDQMVFGRYGTPSVEDYIIHVDVTLKGGLPFERTLPLAAFRA
                     CDDFIQEIRASLKMEDGRNATQVREYFDKIRPNAKKVVIVKQIAGQGAMYDNQLFSKE
                     PSGFEGGTSIIDMGNVPMIISPNEYRDGALRAMT"
     gene            complement(12605..13330)
                     /gene="prdB"
                     /locus_tag="PC494_002064"
     CDS             complement(12605..13330)
                     /gene="prdB"
                     /locus_tag="PC494_002064"
                     /EC_number="1.21.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011986824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_except=(pos:complement(12878..12880),aa:Sec)
                     /transl_table=11
                     /product="D-proline reductase (dithiol) protein PrdB"
                     /protein_id="HDF3912564.1"
                     /translation="MSLTTVQGLQSEIFVPITPPPVWTPVTKELKDMTIALATAAGVH
                     LKSDKRFNLAGDTTFRAIPNTATVDEMMVSHGGYDNGDVNKDINCMFPIDRLHELAAE
                     GFIKGVAPMHYAFMGGGGNQHVFTEETGPAIAAKLKEEGVDGVVMTAGUGTCHRTAVI
                     VQRAIEEAGIPTIIIAALPPVVRQNGTPRAVAPLVPMGANAGEPHNIEMQTHILRDTL
                     EQLVAIPSAGKIVPLPYEYKAHV"
     gene            complement(13368..13652)
                     /locus_tag="PC494_002065"
     CDS             complement(13368..13652)
                     /locus_tag="PC494_002065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3912565.1"
                     /translation="MDRLKYISSETFYEGIIVDIKGGGVTIDLKGRLGQFKIPNRMLI
                     TDYELKIGQEVGFMLSYPEVLSPEPNQEYVENIRREKEKQAEMQSKQEEK"
     gene            complement(13733..15613)
                     /gene="prdA"
                     /locus_tag="PC494_002066"
     CDS             complement(13733..15613)
                     /gene="prdA"
                     /locus_tag="PC494_002066"
                     /EC_number="1.21.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-proline reductase (dithiol) proprotein PrdA"
                     /protein_id="HDF3912566.1"
                     /translation="MSITLETAQAHANDPAVCCCRFEAGTIIAPENLEDPAIFADLED
                     SGLLTIPENGLTIGQVLGAKLKETLDALSPMTTDNVEGYKAGEAKEEVVEETVEEAAP
                     VSEAAVVPVSTGVAGETVKIHIGEGKNISLEIPLSVAGQAGVAAPVANVAAPVASAAA
                     EVAPKVEEKKLLRSLTKKHFKIDKVEFADETKIEGTTLYIRNAEEICKEANETQELVV
                     DMKLEIITPDKYETYSEAVLDIQPIATKEEGELGSGITRVIDGAVMVLTGTDEDGVQI
                     GEFGSSEGELNTTIMWGRPGAADKGEIFIKGQVTIKAGTNMERPGPLAAHRAFDYVTQ
                     EIREALKKVDNSLVVDEEVIEQYRREGKKKVVVIKEIMGQGAMHDNLILPVEPVGTLG
                     AQPNVDLGNMPVVLSPLEVLDGGIHALTCIGPASKEMSRHYWREPLVIRAMEDEEIDL
                     VGVVFVGSPQVNAEKFYVSKRLGMLVEAMEVDGAVVTTEGFGNNHIDFASHIEQIGMR
                     GIPVVGVSFSAVQGALVVGNKYMTHMVDNNKSKQGIENEILSNNTLAPEDAVRIMAML
                     KNAIEGVEVKAPERKWNPNVKLNNIEAIEKVTGEKIVLEENEQSLPMSKKRREIYEKD
                     EN"
     gene            complement(16042..17802)
                     /gene="prdR"
                     /locus_tag="PC494_002067"
     CDS             complement(16042..17802)
                     /gene="prdR"
                     /locus_tag="PC494_002067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-54 dependent transcriptional regulator
                     PrdR"
                     /protein_id="HDF3912567.1"
                     /translation="MFSIPEVKKVEEVMDTKFTTIDEDTRIEDAIKEMIKSNTKTLMV
                     IDSSDQLKGIISMTDIHNLYEMHKKYEGQPVKLIMKKDVIYVNEGLTLDECRDIMILK
                     NIGILPVLRDNKIIGVLKQEHIRDYLYMHLEDYGLTLKYIIGQIKEGICAINNEGVVI
                     LWNKFMEERYDIKSEDIVGRPMNEFLENTISEKVLNSKVGMSDLYFTDKKENMYALVH
                     ANPIFYKEEFIGVVCTEVDVTEAKILALELEKVNDTLKYLKNEVKNLSKGSFDKILGK
                     SYKLEKSKAIAKQVARTNSSIFIWGESGTGKEVFARAIHDYSERKGQFIPVNCSAIPN
                     ELFESEFFGYESGAFTGASKKGRIGIFELAKDGTVFLDEIADLPLSMQAKLLRVLQEK
                     EIRRVGGDTTIKINPRIISATNKDLSKMVKAEKFREDLYYRLNVVEIKIPPLRERKED
                     IGLLVHSFLEEICKQNNKPVLTISKDVIDIFQNYRWKGNIRELKNTIENIVVLSQNSK
                     IDVDDVPSYMMDSTNNSTEEEEYPLDLTKATQKIEIKNITKALKMSNGNKAKAAKILN
                     IPRTTLYYKIDQYKIDVSKI"
     gene            complement(18209..20317)
                     /locus_tag="PC494_002068"
     CDS             complement(18209..20317)
                     /locus_tag="PC494_002068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-Gln thioester bond-forming surface protein"
                     /protein_id="HDF3912568.1"
                     /translation="MKTKIKKSSIISLVIAFSMVFTAFTPIVSYADEVTSNDTILNGE
                     EQSNGQTPDVEKPSDGQVPDGEKPLDGQIPDGEKPSDGQIPDGEKPSDGQIPDGEKPS
                     DGQIPDGEKPSDGQMPDGEKPSDSQTPDVEKPSDGQMPDGEKPLDEQIPEEEKPLEEE
                     IVIEEMSLKQDIDKILDMTLSQINKIVYNFWEDEEDVKADEQSEINQVFTSEDSFISL
                     WYDKKAKVKNSCLLKEIDGSDRPYHDLRFDDITKTLTFDYVIKGLVGASSKDDKYVIE
                     GEDGEQTAFCYNNHLRPPSSNGKSPYLPAEDFNGQENQNEEAVKSILYAGSEFDGFGY
                     KQQFNLGEEENDIMTYSATQSAIWIILGQIDEQERLKQYQGSIDLCDKLIEIAKTEEE
                     RAEYQKRKEVAINTKAYLEALLKAGREELKPNDTGKPSLSNGLTKINFEKNEDGTYET
                     EAVALVGYSGVVKLKLPDGVTAYDVDGNIIGTGEVEISTQQKFKLKSVGKPDAKANIS
                     AVSYDYIFPKAIQYYKAVLDLGQKDHSSSLPSSKQNLLSYTIEKKNGQEVNFNIGLPT
                     DDVVNPPVPPTDDTNGHKPKPSPPIDDTVINPPVPPMDDTIINPPVPPTEDAVLNPPV
                     PPTEDAVLNPPVPPTEDTVLNPPVPSVSDTVEKTPELSRDDTIIKSPKTGDETQLMSY
                     VFISVIAICGLAYQCKIKRN"
     regulatory      complement(20899..20984)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01786"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class II; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01786"
     gene            complement(21387..22700)
                     /gene="prdC"
                     /locus_tag="PC494_002069"
     CDS             complement(21387..22700)
                     /gene="prdC"
                     /locus_tag="PC494_002069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline reductase-associated electron transfer
                     protein PrdC"
                     /protein_id="HDF3912569.1"
                     /translation="MNKLYSILLKQHVGGPDKPVVSVGDVVKKGTLIAEPTGLGANIY
                     ASVSGKISEINDQAIVIEADEVQEDTFEPLKGEGILDLIKEAGVVGMGGAGFPTHVKL
                     NIDLNGGTILANAAECEPLLAHNIKEIEERPEIVYQGIKYAMEVTNAGKGMLAIKSKH
                     PKAIEAFKKVIKPGDNIEVAELVDMYPMGEERAIVRDVLGKLLEPTQLPSEANAVVIN
                     VETLTRIVEAVEQKRPVISKNITVVGQLNSGKESIVFEDVPIGTTVGELIERAGGIKG
                     EYGEIILGGPFTGKATTLDAPITKTSGGIIVTMPFVNEKRKMGLLVCACGPNEERMRD
                     IATKMGVTDIVSVQKCKQAQEIKGALKCENPGHCPGQAQKCIEFKKAGAEVILIGNCT
                     DCSNTVMGSAPKLKLGVYHITDHVMRTVNHPLIRRIKGDVRLKIK"
     gene            complement(23089..23853)
                     /locus_tag="PC494_002070"
     CDS             complement(23089..23853)
                     /locus_tag="PC494_002070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HDF3912570.1"
                     /translation="MKREVKRTKALIYSVLFFSLLLVLIFVFVYGIKYICSKSDNSKM
                     PIYKVDTNEKKIALSFDVAWGTDNMDDILKILDKHNVKATFFLVGSWVDDNEEIVKAI
                     DEKGHEIGNHSNTHANLKEISKEDITKEIETTSEKIYNITGKKTNLFRPPFGDVNNKA
                     MDICSDLGYKVIKWDVDSIDWKELGPNHVIEKVIKESQPGSIVLFHANINDVDNYLDT
                     IISRLKKDGYSLVKISDLLYKDNYVVDSNGVQKTKN"
     gene            24144..24347
                     /locus_tag="PC494_002071"
     CDS             24144..24347
                     /locus_tag="PC494_002071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta-type small acid-soluble spore
                     protein"
                     /protein_id="HDF3912571.1"
                     /translation="MSNSNRTVVPEAKAALNQMKLEIANEIGLSNYENIDKGNLTARE
                     NGYVGGYMTKKLVEMAERQMAGK"
     gene            24538..25074
                     /locus_tag="PC494_002072"
     CDS             24538..25074
                     /locus_tag="PC494_002072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4364 family protein"
                     /protein_id="HDF3912572.1"
                     /translation="MFENSSEELAYHKLLILYILEKIKMDLTNSQITQVVLETEMMNY
                     FSLQQLLSQLMESKFLTTYKDSDREYYALTQRGVESLEYFFNRIPTSVTEKIDKYIDS
                     NKENLLADTQVKSSFVKQSDNEFIVNLRVIENQSNLIDLNLNVSSEKQAKLICNNWKN
                     NASYMYAEVIDLLIRDIH"
     gene            complement(25078..25944)
                     /locus_tag="PC494_002073"
     CDS             complement(25078..25944)
                     /locus_tag="PC494_002073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YncE family protein"
                     /protein_id="HDF3912573.1"
                     /translation="MKIYISNYLSKSISIVDYSTLELEKEIVLEDNIYPHHFCIEKEK
                     NLIYIPSSSNGILYVLDLSNDKIIDTVSIGGSLSQVVLSDNELFVANEDSNSIYVLDK
                     NTLNPIGIIGVDNMPHGFDFDRESKKLYVPCINSIVCIDTINKNIQKKINMDFRAWHI
                     ELDKQKKEMYISTLDGKLIIIDEVSMDIKKVLYEFLLPVEIRFNYSGKKVYVADLGYN
                     NVRILDYTTSRYIGNIEINGIPQGLEISKDEKLLFVSDTQENSVKVYETANNKLIKEI
                     KVGKEPTTIICL"
     gene            26092..26337
                     /locus_tag="PC494_002074"
     CDS             26092..26337
                     /locus_tag="PC494_002074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03905 family TSCPD domain-containing
                     protein"
                     /protein_id="HDF3912574.1"
                     /translation="MKVTFNPSGVCCREMIFEVDENNVIVDAEFIGGCNGNLSGLRSL
                     IIGQNALEVADKLNGIDCGGKGTSCPDQLSKAIRQSI"
     gene            complement(26451..27749)
                     /locus_tag="PC494_002075"
     CDS             complement(26451..27749)
                     /locus_tag="PC494_002075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HDF3912575.1"
                     /translation="MKYEEALEYISQTNKFGIRLGLENIGKLLELLGNPQETLNIIHV
                     AGTNGKGSVCSFVSNILRECGYKVGLYTSPYLETFTERIRVNGQNIPQDDVARIIELI
                     KEKIEIMVKEGYAYPTEFEVVTAMAFYYYSEQKVDFVALEVGLGGRYDATNIITKSLV
                     SVIVSISLDHTGILGDTIEKIAYEKAGIIKENGVVLVYDQTDEAKDVIKSVCKEKKAK
                     YIEVDFDDINIKKSDINSQIYDCTVMKETYRDLEIKLIGEHQINNSILAISVIKYLKD
                     INKLANINEESIRKGLINTKWPGRIEKIKENPIFIIDGAHNEDGAKSLAKALDKNFKG
                     RKLTLLIGMLEDKDIDSVLEILLPHFNKVITTTPNNPRAINSDILREKVLKYVDDVTS
                     KHEIEDAVNYTLETSSEDDIIISAGSLYMIGTVRTLVKKL"
     gene            complement(27882..28913)
                     /locus_tag="PC494_002076"
     CDS             complement(27882..28913)
                     /locus_tag="PC494_002076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HDF3912576.1"
                     /translation="MENICDMNNKVKVAVLDTGIDKEHDYLKDNLVGGIAFECMHDYI
                     FISDKFDDEDGHGTACASIIKKEYEDVELFVIKILRKDGITNIKVLEEALRYLLDTNI
                     RLINLSLSVIGVESVKGLFEVCYELFRKGKIIVCSLANDFDLSYPAMFNNVIGVRGFT
                     LDGDDSFWYNKKYDVQCVMDSNSYISCDINNSYRLPPKCNSYLSAKLTGKIAKILSEK
                     PGITISDLNDKLESLATRNHWDSCDFDECSRIVNFKLDLYDKENALFMKVADVVRDCL
                     DIEENNEKLFKGSLFNKEIGLVYDNCFNLLKKLEHRFDIKFNYMDISKYDLVSIYTLT
                     ELVERYKNL"
     gene            complement(29959..30669)
                     /gene="rgaR"
                     /locus_tag="PC494_002077"
     CDS             complement(29959..30669)
                     /gene="rgaR"
                     /locus_tag="PC494_002077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator RgaR"
                     /protein_id="HDF3912577.1"
                     /translation="MFRVVICDDEKIQRSILKEFTEKLLSERCLNYQILEFSCGEDLI
                     SKYPEKIDIIFLDIQMKDINGIEVAKKIRKFDEKVEIIFTTAFSEYAPQGYEVRAYRY
                     LVKPIEYSNFAMGVNLCIDNLQRKKERYIVLNSKKGFNRILIDSILYVETVKRDLVVH
                     TIGRDYKANMSMKQAEKLLCENGFFRCHTSFIVNLRRIEDLRDNMITINEQFIPISKY
                     RLKDLKVALTSLLCDIMY"
BASE COUNT         9306 a         5735 c         3504 g        12342 t
ORIGIN      
        1 ctatttattg gtatatgaaa tcatattgtt tattatttta taatcttttc atcatataaa
       61 ctattgtatt ctataaactg atacatatcc agctgcagaa gtacctgtcg tgcctgaacc
      121 aaatgtaaaa cttaaagtaa cagctgctgc tctagcatca actaaaaagc ttaaacttac
      181 acttacatct gatgaagtaa gtgtatttac tgcttttgca ataaagttat tttgagctac
      241 tccattaaag ttagtagtaa ttgacataaa tcctgcaagt gaaagtgtgg cacgtatacc
      301 gaaagataca ttgtatatcc ctccaactgc aagatttata gtactacttg ttggaaaagt
      361 tatattagtt ccatttataa atgatgaatt aaatgtcact aatgtattat tcactaaact
      421 tgaagaggac actgtaaatt gtgcattgtt tgttgctaac actcctgttg ctcctgtcgc
      481 tccggttgga cctgttgctc catttgctcc tgttgctccg gtcgcccctg ttgctcctgt
      541 cgctccattt gctccagttg ggcctgttgg tcctatcgct cctgctactc catttgctcc
      601 cgttgctcct actgctcctg ttgggcctgt tgctccattt gcccctgttg ctcctgtcgc
      661 tcctgttgct cctgctactc catttgctcc ggttggaccg gttggaccta ttggacctgc
      721 tactccattc gctccggttg ctcctactgc tcccgttggg cctgttgctc catttgcccc
      781 tgttgctcct gtcgctcctg ttggacctac tgctccatct gctcccgttg ggcctgttgc
      841 tcctactgct cctgttggac ctattgcccc agctactcct gttgctcctg tcgctcctgt
      901 tggacctacc aaaccatttg ctccggttgc tcctactgct cctgttggac ctaccaaacc
      961 atttgctccg gttgctccag ttgggcctgt tgggcctgtt ggacctacca aaccatctgg
     1021 acctgttgct cctactgctc ctgttggacc tacctctcca tctgctccgg ttggacctgt
     1081 tgctcctatt gggcctgttg ccccagttgt tccggttgct ccagtcgctc ctatacttcc
     1141 ggttggacct gttgctcctg tatttcctgt tggtcctgtc gctcctgtta ctccatttgc
     1201 tccggttgct cctgtatttc ctgttggacc tgttattcca tttgctccgg ttgctccggt
     1261 tgctccagtt agtccggttg gacctgttgc tccagttgct cctgtattcc ctgttggtcc
     1321 tgttattcca tttgctccag tcgctcctgt atttcctgtt ggtcctgtag agcctgttat
     1381 tccatttgct ccagttgctc ctttgtttcc tgttggtcct gttattccat ttgctccggt
     1441 tgctcctgta ttccctgtcg gacctgttat tccattcgct ccagtcgctc ctgtatttcc
     1501 tgttggtcct gtagaacctg ttgttccatt tggtccagtc gctcccatat ttcctgttgg
     1561 acccgttatt ccattcgctc cggttgctcc cgtatttcct gttggacctg ttattccatt
     1621 tgctccggtc gctccagttg cacctctagg ccccgtcggt cctgttggac cagtagcacc
     1681 tgttggccct gttggaccta catcttgata taaacttgga cctgaaatat cactcatata
     1741 attaatcctc cttttttaaa gttagagtat tactctataa atattgagta ttactctata
     1801 taattatatg aatcgacaat ttcttatgtg ataatgtatc tatttgctta tatcaacata
     1861 tatgctttga ttcttgaatt tcattacttt tttgtaaaat cttttacaat tattagtact
     1921 cttttacaat tattaataca attaaaaaac tcatttccca tcaattattt aaaatttttt
     1981 tattatgtta taaaaaatag ataattaaat tgcataaaat taatttaata ctactttaat
     2041 tactttttaa ataaaaaaac ctcaacacga ttaataaaaa tcatattaag gcatccacaa
     2101 aattatataa ttgcttatct atcttcatca gtaacattga atatataagg aacatttcta
     2161 taataatcac caaaatcaaa cccatatcca accacaaact tatcttctat ttcaaatcca
     2221 caataatctg gcactaaatc gacttttctt ctgcttggtt tatccaaaag aacacagcat
     2281 tttaaactag caggattttt agcttttaga tgttttaaca caaaatccat agtaagtgca
     2341 gaatcagtaa tatcgtctac aaccaaaaca tcatatcctg ctatatcagt agtcacatct
     2401 gaaactactt taacccttcc agtactttct tcattgtttc cataactaga tgtagtcata
     2461 aaattaactc taagtggtaa atttatattt ctaactaagt ctgcacaaaa tataaagcta
     2521 ccttttaata gagaaactac cataagattt ttatctttat aatctttttc tataattgct
     2581 cctaattccc ttaatttatc tttaattttt tcttctgaat acaatacttc ccattttttt
     2641 gtttctatat ccataaaaag acctccaatt gtaataatcc ttcttaattt tataagagat
     2701 tgctcacttt ttcaatactc ttattcaata ttagtcaata ttattgagtt tttatgttca
     2761 ttcaacaatt attaacaatg tatcttatat tttaagtagt tcatatatcc acactaaatt
     2821 acatactata tattttagac aaaaaaagaa aaaacttgca ctaacaagtt ttttctatta
     2881 tacataaatt tatacataat catattttat tagagggtac taattaaatt tatttatgct
     2941 atttttgtta tacctcataa tacaaaacat attataaagt actagtcaac tttattcata
     3001 tcattcatta catttaagat tatctcatct gttatagaca tacctttgtc acttactcta
     3061 cctaagtttt gtatactttg ctcaacactt gaaccaacta taccatttag tggtggtaca
     3121 aaacaatctt gcttagctat tatagcactt tgtatagctg cagatgctgc agaagataat
     3181 tttaatgcac aaccagcttt cgcaccgtca catatcattc cacttaagtc agctatcata
     3241 ttttctatag ctccttctat ttgcttttca gtaccattca taagccaaga gataccagca
     3301 gttgctccag tagaagcagc aacaccacat ccacatacag cagataatct tcctgtatag
     3361 ttcttaatat aaccagttac tagatgagat atagctaaag cttttgctag tctttcatca
     3421 gattgtggga attttttatt ataagcaacg attggaagaa ttgctgttaa tccatgattt
     3481 ccacttccat ttgaactcat aacaggcatt tttacccctg ccattcttgc atctgaagct
     3541 ccagcagtta acatcattgc ataatttata acatcattac ctaaaagacc ttcttctata
     3601 gactttttaa ttccatatcc tacaccaata ccagtttttt gttttaatcc atattcagcc
     3661 atctcttcat tcatttttac tccatctagt aaaaattcta tatctttaaa atcaattcct
     3721 tctacatttt ttattaattc ttgtatagtt actgtatcca ttaaactttc agctttttct
     3781 gccgcatcat ttgaagctga tacttttggt tcattgtcta ataatacttc tccatctttt
     3841 tctaagaacg taaaattatc atgtttagtt cttattctca ctttagcaat atgatttttt
     3901 ccttttaaca caacttctat aaatactttc tctcttgtat cagcaggtgt tattgatagt
     3961 ggagtattat ccatataatc ctcagctatt ttaacttcct cttttgttag agtttctaac
     4021 acacttaatc cattttcaga atgtccacct actataccta gagctgctgc aatttttaat
     4081 cctaatcttt cagtacctgg tatacctacg cacataccat ttttataaat actaggacta
     4141 actaacatac gattttcaac tatttcttct cctaataatt cctttgcctt tgcacatgct
     4201 agagctaagg ctactggttc agtacaccct actgctggtt taacttctgc ctttaacatt
     4261 tccactaatt cttttcttat atctctcatt atatataaac ctcccaatta agtttagatt
     4321 tagtactcaa ataattaatt aaataatttc ttatctatat ttatagcaaa atacatgcca
     4381 tattttttat atctttttat atttttagtc ttatattcta taaccattgg tatgactgct
     4441 tctatttatg tatttttttt atttacatag agtatttata ttctttaaaa tggagaaaca
     4501 tatgacaatt tcgcaaaaag acaaaaaaaa gtctcaaaat gagattctat atcattttga
     4561 gacggctcaa atgtattatt ttttaactta taaaaaccat tttttaattc ataaaaaaag
     4621 attctgcaaa acacttatag tataagttta aagctttctt taaagttatg aatttagaaa
     4681 aatttaaatt ttatatagct ttttattata ttactatgaa attatattgt atttttcaat
     4741 ttttctatat aatgtagctc ttgatattcc aagtgcttta gctgttaatt ctttatcttt
     4801 tttataatct ttgtacttat ttaaagcttt tattatctca atcttctcta gttcatcaag
     4861 tggaattatc ctatcgcttt taacttctaa ctcttctaca gaggtattct taattttttg
     4921 aggaattaca ttcattgtga ttattgaaga agaagacata ttcacactat attcaataat
     4981 attctgcaac tctcttatat tccctggcca cttatattcc atcatagcat caacaaccct
     5041 gctatctatg tcaataacat ttttatctaa tttttttgaa tactctttaa ccatatgctt
     5101 gattataagt gggatatctt cttttctctc tcttaaactt ggtaatttta taggtataac
     5161 atttaatcta tagtataaat cttctctaaa agtgccattt tgaaccattt tttctaaatc
     5221 tttatttgta gcagcaataa ttcttacatc tattgaaaca tttgatttac ttccaatttt
     5281 attaagttcc ttttcttgta atactctcaa taactttgac tgtaaatgca aactcatatc
     5341 tcctatttca tctaaaaata tacttccctt atgagctact tcaaacattc caagctttcc
     5401 acctttttta gctccagtaa aagctccctc ttcatatcca aataattcac tctctaataa
     5461 attgtctggt atagcagcac agtttacagc tataaaagga ttatctactc tattgctatg
     5521 gttgtgtatg gctcttgcaa atagctcctt acccgttcca ctttccccag taataagtac
     5581 tgttgatgtt gatttagaag ctattagggc ttccttttta gaatttctta tagctacact
     5641 ttctccaatt atgttttcca attttattct ataatcttta ttcatcttat tgtagttttt
     5701 tatagcatct ctcttatcta taaaatcaat aacatatccc tttaactcat tttttaatac
     5761 tattttattg atgttgtata ttcccttcga atcatatccg tatcttttat aaaaaaaact
     5821 acaggatttg tccttcttaa agttatttat agaaggtttc tttataaaat ctaattcgac
     5881 aaatatgttt ttgccagtta tactatcttt tatattgaaa agctctttaa attttgaatt
     5941 atatttatca atttttccgt ccacatcaat agacacaaca gctttgtcca tattgtttaa
     6001 tagtgtctct aattttttct tttctaattc aagctcataa gttttaattt gtgcttttaa
     6061 tttattagat attaggtctg ccattttgcc taaaaagttt ataagaccac ttttattatt
     6121 ttctataatt tgtgcttgtt cttttgtaaa ggctataagg cctataacac catgagaatc
     6181 gccatcacat ataataggac aacacacctc tgcaaactct acacaagccc cacttttata
     6241 gcattcccta catatatcac tactctttgg gtcatcaatt agtattgtaa tctgttctgt
     6301 aagtgatttt ttaaaagccg tatatttatc tactttctca cctattttgt ctatatatac
     6361 tcctgtacct gcaatcctaa ataactcctt atttactata gttacatcta tattgagtac
     6421 tgatactata gcttcagcta tattttgaat atcagatttt atatattcta aacctatcat
     6481 aatcatcatt ccttattttt ctttagcata agtatttgtc ttatttcttt aagaatcaag
     6541 tatatcttat ttaaagtaaa ttggattgac atcaggatta caaagagcat aacaattatt
     6601 attaactcat aatttatttc catctaaaca tctccttata acaaaagact aggcttaacc
     6661 tagtctttta tattatatcc atatttatat tttaactcat ttatcttctt tttcccacat
     6721 aaatatattt taatttattt gactctttaa tcataccatc aaagtttaat cttgaaaata
     6781 tattaaatac ttcatgtgga tagtgaatct ttgcaacaga accacaaaat ttatgtttaa
     6841 gatagtttaa cttaactttt aaattcttta aatttaaatc ctctaatata acctctccat
     6901 tgccctttaa cactctttgt atttcagatg aagctttttc acaatctgta ataacattaa
     6961 attggtcaac tattattatc ttgttgaact gattatcatc aaatggtaga aactctaact
     7021 tacctttaac tacattgcaa ttttcattat acactagaga ataacagaca tcttcataat
     7081 tactattctc cagtatagtt acagaagttc caagacctct caatctcttg cctaggtttc
     7141 ctatatgacc aacaagcaat attttatcac ctacattata ctcaattgta tccaaaaaac
     7201 attctaattc atcagatgta tatttagctt taactggctg tttatttatc tgacataata
     7261 tgcttttcac aatgcttcac ctcttcattt cctcaattat aaattatgta cagattacat
     7321 tataataaat ggcgagcaac tattcaagag atatttcatt agtatttttt taaacaatct
     7381 ttatacattt taatatgata ttataccaaa tttattagga ttttattcat aaaaatcagt
     7441 ctatttttta tgtttattca ttgttatttt catccaattt ttttattttc gatatggata
     7501 cttcatatgc catttttttg accacattat tttcatctat ttttttctca tattctctac
     7561 tttgaaccct accccaaagc tgtattctat caccaacctt tagattcttt gcaaatttag
     7621 catttctacc ccaaactatt gatggtatat aatcagattt attataaggt ctgtttatag
     7681 caactaataa atcggttatt tcccttccta aaggtgtctt cctatacaca ggttccttac
     7741 atacatatcc atctaaaaat atactattag ggtctttatt ttcctcgtct atacttttta
     7801 tttctctgac aaacactgta agcactaatc tatttttatt atttaatgtt ttgttatatg
     7861 atcttaattg gcctacgaca ttgactaaat tttgtttatc aaggtcaata tcttggagaa
     7921 gtctttctga tacagtcatt ggaagtatat caaaagaatc gcttagtctg tttattttta
     7981 ttttcatatt ataaaatttt tctccaaata tctcatggct aaattctagc ttattgtcta
     8041 actcccctct taagtttact acgttattct catctttaac agctatcata ttttatccct
     8101 ccacaattgt taattcttat atttctggta tcagcttata taataaatat atttataagg
     8161 gatgtatttt attacaaatc tttgattgct gtttaaaagt ttttatttag ttataaattt
     8221 catttaatat ttcactttta taattataaa attattatct ttttgtacca catatactaa
     8281 ttaaactacc tatttcagtt ttgtattaat tataaaaatc ctattatata attaataagt
     8341 catatataac ttaaatttat tcactctata taagcaactt caacgaatta aatttattga
     8401 aataattcag atgaatattg agtcattata aacttatttt tcttaattat aagttatatt
     8461 agacttatta caggttatat ttttattaat ctgtattaat atatgaacat ttattgaact
     8521 tattgattat aaaatttaaa tatttagctt taaattatgc tttattcttt aaaaatacaa
     8581 cgttttttag attaaatcta ctaaatcact atatatatta cataattggc atgttaattg
     8641 ctttatatta atttagtaaa taaaaaactg ccctaaaata ttaattcaat attttaaagc
     8701 agtttataat ctttattatt agctgtaata tttaataaac actaagtagt ctttaactaa
     8761 gcagtctttt tgtttttatt tgcagccatt atcattgtag cagaagtata agctataact
     8821 actattacta atgcttttaa tatatccatt ggtagagttt ttactatata tgcagctacg
     8881 aaaactccta ttaaaccaca tatagctatt ataactgatg cttttttagt atatgcatct
     8941 tcttttatga atttcatact tgcaactggc attaataatg cacaagaacc cataactatt
     9001 gggaatgcaa cttttgcaga cattcctaag aaataaacca ttgccatacc tggagcatat
     9061 agacctatac cagctgtcat taaagctcct agtataaagt tacctattac acctattact
     9121 aatttagcac cagtaagacc taattcattt cctccacctg gtaatacgtt aatccaagga
     9181 tgacctaata acattaatat tgctgttaat gctaaagtta cacccataac aagttgtatt
     9241 tttctctcgt ccatcttagc tattattcct gcacctatat atgaaccaac tgctgctgcc
     9301 acaaccatag atactaaagt aacaccatct actgggataa ttgatgtaaa tatgaatgct
     9361 tctgtaacaa ctggaatagt atgtgctacg tttaatgtac caggcatttt tttatctggt
     9421 atatttaact ttaaagcctt tgacattgct attgttggag caaatgaccc tattcctaat
     9481 gtatcaaaga agtctgttat aaatcctgtt acagcaactt ttggagtact ttgttcttct
     9541 agtttcccct ctttgtttgc tttagctacg tctttaccaa acacaactgc aaagattgct
     9601 gcgaatacta catataatgc ctttaagatt gctaccataa tccatcctcc tattttttta
     9661 ttttttcata tattctgaat cttatagcct aaaagctata gaatagcaac cgacaagtgg
     9721 ctactattct attttaattt cctaatttat ttattactta tttaagaata aatccatgtt
     9781 taagtgggtc ttcttcatct attacaaaat gattaaatcc agttatataa gcagaaccag
     9841 ttattttagg tactacagca ttgaaatctg caactttagt ttcttcaact atttcacctt
     9901 tgaataaagt tcctaatata ctttcatata cgaatttttc tcctactttt aattcacctt
     9961 tagcatgtaa agtagctaat ttagcacttg ttccagttcc acatggagat ctgtcaactt
    10021 gaccttgacc aaatataact acatttttgt aagtagcttc tggatgagtt ggctcatcat
    10081 atatttcaac taagtctaca gtttttatat gagctaaagt tggatgttgt atttctattt
    10141 tctcatttat tatatctcta agtttcatag ctagttcagt taatttacca gcattttgag
    10201 gttcgatttt taaacctaat tgacttgcat gtattatagc aaagaagctt ccaccaaatg
    10261 atatgtcaaa tttaacagtt ccaacacctg gtaagtcaac ttcaacacct tctttatata
    10321 agaaagctgg tacgtttaag aatgatactt ctttagcttt tccatctaca actgtaacgt
    10381 ctcctcttat tattcctgct ggagcttcca taactacatg agttacaggc tctactgctg
    10441 gaactacacc tgtttctata gctgctgtca tagctcctat tgtaccatgg ccacacatgt
    10501 taaggtatcc gccaccatcc atgaagatta ttccaaagtc agcatctggg caacaaggtt
    10561 gagtcattac agaaccaaac atatcattat gtcctcttgg ctctaacatt atagcagttc
    10621 ttaaataatc tagattttcc tctaaatatt cttttttctc aggcatagaa tttcctttta
    10681 tgttaggtat tccacctaca actattctag tcgcttcacc tgctgtatga gagtctatag
    10741 cttgtatact tctgctaaat ttcatatcaa attccccctt aggtttattt tgcgtcttta
    10801 cgcattttta attttaggaa agccaatgct tttttaacat caacttcatc catgtgattg
    10861 tctccaacta cttctgtttc tatgtagcct gttgtctttt tataatcaat tatggtagct
    10921 ttatccaaat atggattggt aattactaat ccatctgctc ccataatagt aagacctact
    10981 gtaggtatat ctgattttac aaactctgct atagcatttg taaaatcaat atgctggttt
    11041 cctgccatat ctaaagttat aatcactcca tcaggtcgca atgattcaat ccatcttcca
    11101 agtctagttg ctaaaaatgt tttccattca ttgtgctctg atgtcccaac tacaaccact
    11161 cctaacaagt ctatgtcaga atcattatct atcaaatcta gtaacgggtc tctaaatata
    11221 tgaagtgatg tgtttttcat tgatgtagaa attcccacaa aactcattcc cttacttaaa
    11281 ttttttatcc atgttttctc attttaagtt ttaaaaatgc caaagctttt ttagcatcta
    11341 tttcatttgt gttgttttct ccaactactt ctgtctcaat accttctttt gatttgttca
    11401 tatcaactat ggtatccata tattgattgc ttacaacaaa cttagcttga gtcccattaa
    11461 atgtaactcc aactacaggt atatctcttt ttcctatttc ctcaaatgtg ttagcgtagt
    11521 caacatgtga gtttccccaa ccatctgatg aaactatagc tccatctact ctcatggctt
    11581 ccagccaagc ggccgttctt tgtcccacaa aggttttatt ttcatttcca tctggagttc
    11641 ctactactat tactccaagt aaatctacat ccttatcact ttcaactatg tctaaaagtg
    11701 ggtctctaaa gtgatgaaga gatgtttctt ttgttgaagg tcctattccc ataatatcca
    11761 cctctcttaa gtcatagctc taagggcacc atctctgtat tcattaggag atataatcat
    11821 aggtacattt cccatatcta taattgatgt tcctccttca aatccactag gttcctttga
    11881 gaataactga ttgtcataca tagcaccttg acctgctatt tgttttacta tgacaacctt
    11941 ttttgcattt ggtcgaattt tgtcaaaata ttcacgaact tgagtagcat ttcttccgtc
    12001 ttccattttc aaagacgctc ttatttcttg tataaaatca tcacatgctc tgaatgctgc
    12061 aagtggaagt gttctttcaa aaggtaaacc tccctttaaa gttacatcta catggattat
    12121 ataatcttca actgatggag ttccatatct cccaaatacc atttggtctt tcaaaattcc
    12181 ttctgaagaa ccaaattcat gcatttgatt tccatcttca tctgcaccag ttaacattac
    12241 atatacaccc gttaaagtat gtgtaatacc ctctcccagt ctgcctaaaa cttttgttga
    12301 tattggtata atgtccataa tagtattaat ttctctgtca taatctccag gttttataat
    12361 gtctactttt atgtctgtta ttaactcttc tctttctttt atttcatcta tacttgataa
    12421 atctattgta agtacatctt tctttataga agtttttgaa ccgaaattaa cttcattcat
    12481 atgaaacggt tttataacaa gtcttctcat tattttttct tccataatat ccacctttgt
    12541 tcttaaaacc cctctcctaa ccgtgtagga gaagggttct atattttcaa atataaatta
    12601 cattttaaac gtgagcttta tattcgtatg gtaatggaac tatcttacca gcagatggta
    12661 ttgcaactaa ttgctctaat gtatctctta atatatgtgt ttgcatttct atattatgtg
    12721 gttcaccagc attagcaccc attggaacta atggagcaac tgctctagga gttccgtttt
    12781 gtctaactac tggaggaaga gctgctatta ttattgtagg tattccagct tcctctattg
    12841 ctctctgcac gatcacggca gttctatggc aagtacctca gccagctgtc ataactacac
    12901 cgtctactcc ctcttcctta agtttagcag cgatagcagg accagtttct tcagtgaaga
    12961 catgttggtt tcctccacca cccatgaatg catagtgcat aggagctact cctttgataa
    13021 atccttctgc agctaattca tgtaatctat ctatagggaa catacagttt atatctttgt
    13081 ttacatctcc attgtcatat ccaccatgtg ataccatcat ttcatcaact gtagctgtat
    13141 taggtatagc tctaaatgta gtatctcctg ctagattaaa tctcttgtca gattttaaat
    13201 gaacaccagc tgctgtagct aaagctatag tcatatcttt taattcttta gttacaggag
    13261 tccaaactgg aggaggtgtt attggaacga atatttcaga ttgaagtcct tgtactgttg
    13321 taaggctcat atatttcctc tcccttctat tttcaaacga ttatttatta tttttcttct
    13381 tgttttgatt gcatttctgc ttgtttttct ttttctctcc taatattttc tacatactct
    13441 tgattaggct ctggacttaa tacctcagga tagcttagca tgaatccaac ttcttgacct
    13501 atcttaagtt cgtagtcagt tataagcatt ctattaggta ttttaaattg tccaagtcta
    13561 ccttttaggt ctatagtcac tccaccgcct ttgatgtcaa ctataatacc ttcataaaaa
    13621 gtctctgatg agatatattt taacctatcc attataattc tacctctcta tactgtttta
    13681 aacttggatc taaatttatg ttattgtcta aatcttagtt agtatctaaa ttttagtttt
    13741 cgtctttttc gtatatttct cttctcttct tactcattgg tagagattgc tcattctctt
    13801 ctaatactat tttttctcct gtaacttttt ctatagcttc tatgttattt aatttaacat
    13861 ttggattcca ttttctttca ggagctttaa cttctacacc ttctatagca tttttaagca
    13921 tagccattat tctaacagca tcttctggag ctaaagtgtt gttagataat atttcattct
    13981 ctataccttg cttagactta ttgttgtcta ccatgtgagt catgtattta ttaccaacaa
    14041 ctagagcacc ttgaacagct gagaaactta caccaactac tggtatacct ctcataccta
    14101 tttgctctat gtgagatgcg aaatctatat ggttgtttcc gaaaccttca gtagttacta
    14161 cagctccatc aacttccata gcttcaacta acatacctaa tctcttagat acatagaatt
    14221 tctcagcatt tacttgtgga gaaccaacaa atacaacacc tactaaatct atttcttcgt
    14281 cttccatagc tcttattact aatggctctc tccagtaatg tcttgacatt tcttttgatg
    14341 caggtcctat acaagttaat gcatggatac caccatctaa tacttcaagt ggagataata
    14401 caactggcat gtttcctaag tcaacgtttg gttgagctcc taatgtacca actggctcaa
    14461 ctggtaatat taggttatca tgcattgcac cttgtcccat tatttctttt ataacaacaa
    14521 ctttcttttt accttctctt ctgtattgct ctattacttc ttcatcaact actaaagagt
    14581 tgtcaacttt ctttaatgct tctcttattt cttgagttac atagtcaaat gcacggtgag
    14641 cagctaaagg tcctggtctt tccatgttag ttcctgcttt tattgttact tgacctttga
    14701 tgaatatttc acctttgtca gcagcacctg gtctacccca cattatagta gtatttaact
    14761 caccttctga agaaccaaat tcacctattt gaactccatc ttcatctgta ccagttaata
    14821 ccattacagc tccatctata actctagtta tacctgaacc taattcgcct tcttctttag
    14881 tagcgattgg ttgtatatct aatacagctt cactgtaagt ttcatattta tcaggagtta
    14941 ttatttctaa cttcatatct acaactaact cttgagtttc attagcttct ttacatattt
    15001 cttctgcgtt tctgatgtat aaagtagttc cttctatttt agtttcatca gcaaattcaa
    15061 ctttatctat tttaaagtgt tttttagtta agcttcttaa aagtttcttt tcttcaactt
    15121 ttggagctac ttctgctgct gcacttgcca ctggagcagc aacgtttgct actggagcag
    15181 caactcctgc ttgaccagct actgataaag gtatctctaa gcttatgttc ttaccttcac
    15241 ctatgtgtat tttaactgtt tcacctgcaa ctcctgtgct tactggaact actgctgctt
    15301 ctgatactgg agctgcttct tctactgttt cttctactac ttcttcttta gcctctcctg
    15361 ctttgtatcc ttctacgtta tctgtagtca ttggagaaag tgcatctaaa gtttctttta
    15421 acttagctcc tagtacttga cctatagtta atccattttc tggtattgtt aataatccag
    15481 aatcctctaa gtctgcaaat attgctggat cttctaagtt ttctggcgct ataattgttc
    15541 ccgcttcaaa tctacaacaa caaactgctg ggtcatttgc atgggcttga gctgtttcta
    15601 aagttattga catagtataa aatacctcct tacattattt tcttatttat tattttaaat
    15661 ctcaattcct caacaggtaa ccccttaact gagaaattaa gtaaattaaa acctacataa
    15721 tttgttatga ttaatattat ttttttctca cttaaagtca ctttatatta taagcaattc
    15781 ctatgccaac ttattaacaa aaagattttt tctataatag attcttcatc tatcgctatt
    15841 tttagccaaa tattatataa atatttattt aaaatatgtt attttttgta tttgtaaaca
    15901 ttttctcaaa caaaaaaagt gtcaattaat caacactttt tcattttttt taacacatct
    15961 atatacacaa cacttatata agcgttggct ttactaggtt ttaaattaaa gtttatcatt
    16021 ttgtcaaaat ttagtcatgt gtcatatttt agacacatct attttgtatt ggtctatctt
    16081 ataatacaaa gttgttctgg gtatatttaa tatcttagct gctttagctt tatttccatt
    16141 agacatttta agtgccttgg ttatattctt tatttcaatt ttttgagttg ccttcgttaa
    16201 atctaaagga tactcttctt cttcagtact attatttgta gaatccatca tataacttgg
    16261 tacatcatcc acatctattt tagaattttg tgacaataca acaatatttt caatcgtatt
    16321 ttttaattct ctaatattac ctttccatct ataattctga aatatatcta ttacatcttt
    16381 gctaattgta agaacaggct tattattttg tttacatatc tcctctaaaa agctatgaac
    16441 caataatcct atgtcttctt ttctctctct aagtggagga atctttattt caacaacatt
    16501 taatctatag tataaatctt ctctaaattt ttctgccttt accattttac tcaaatcttt
    16561 attggtagct gatattattc taggatttat ttttattgtg gtatctccac caactcttct
    16621 tatttctttt tcctgtaata ctctaagcaa ctttgcttgc atactaagag gtaaatcggc
    16681 aatttcatct aaaaatacag ttccatcttt tgcaagttca aatataccta ttcgaccctt
    16741 tttacttgct cctgtaaacg cacctgattc atacccaaaa aactcacttt caaataactc
    16801 atttggtatg gcactacagt taacaggtat aaattgacct tttctctcac tataatcatg
    16861 aatagctctt gcaaatactt ctttacctgt accactttcg ccccaaataa atatgctact
    16921 atttgttcta gccacttgtt ttgcaatcgc tttcgatttt tccaatttat aacttttacc
    16981 taaaatctta tcaaaactac ctttagataa atttttgact tcgttcttta gatattttaa
    17041 tgtatcattt actttttcaa gttcaagagc taatatctta gcttctgtaa catcaacttc
    17101 tgtacataca acaccgataa attcttcttt ataaaatata ggatttgcat gaactaatgc
    17161 atacatattt tcttttttat ctgtaaaata caagtcactc attccaactt tactatttag
    17221 tactttttct gaaatagtat tttccaaaaa ttcattcatc ggtcgaccaa ctatatcttc
    17281 agactttata tcataccttt cctccataaa cttattccac aagataacaa caccttcgtt
    17341 atttatagca caaattcctt ctttaatttg acctataata tacttcaaag ttaatccata
    17401 atcttctaaa tgcatatata gatagtccct aatgtgctct tgttttagaa ctccaataat
    17461 tttattatct ctaagaacag gaagaatccc tatatttttt aatatcatta tatctctaca
    17521 ttcatctaag gttaaacctt cgttgacata tattacatcc ttcttcatta taagttttac
    17581 tggttgacct tcatactttt tatgcatctc ataaagatta tgtatatccg tcatggatat
    17641 aatgcctttt aattggtcag atgaatctat taccattaga gtttttgtgt tgctttttat
    17701 catttctttt attgcatctt caattcttgt gtcttcgtct atagttgtaa attttgtatc
    17761 cattacctct tctacttttt ttacttctgg tatcgaaaac ataaagtccc ccctttatag
    17821 tagtacctca tcaaaactta tttatatata tttattctag catattataa taattattta
    17881 ttaaataatt attattaaaa tttattaagt aattagcatt taaatttata taatcacttt
    17941 aaaatttata attaaattta tacaaatgaa atcaaatgaa ttataccctt agtatattat
    18001 tttttcaata ctattttcac cttcaaaaca tttttctatt catcaaacaa ttaatgaatg
    18061 cctgtatcca atcataaatt taagaatata attaaaatat atatttttaa acaaactata
    18121 tttgcatatt atatttacat aaaaaagccc caaaatgact tataaatcaa tttgagactt
    18181 tttattttaa acttaataat aatctagatt aatttctttt tattttacat tgatacgcta
    18241 atccacaaat tgcaatgaca ctaataaata catatgacat tagctgagtt tcatcacctg
    18301 tttttggtga ttttattatt gtatcatctc ttgatagttc tggagttttt tccactgtat
    18361 cacttactga tggtactggt ggatttaaca ctgtatcctc tgttggtggc actggtggat
    18421 ttagcactgc atcctccgtt ggtggcactg gtggatttaa cactgcatcc tccgttggtg
    18481 gtactggtgg atttattatt gtatcatcca ttggtggtac tggtggattt attactgtat
    18541 catctattgg tggtgatggt tttggcttat gtccatttgt atcatctgtt ggtggcactg
    18601 gtggatttac aacatcatct gttggtagac ctatattaaa gttaacttct tgaccatttt
    18661 ttttctctat tgtataactt aataaatttt gcttactaga tggtaatgaa gatgaatggt
    18721 ctttttgtcc taaatcaagc actgccttat aatattgaat agcttttgga aaaatataat
    18781 cataagatac agcagaaata ttagctttgg catctggttt tccaacactc ttaagtttaa
    18841 atttctgttg cgttgaaatt tctacttcgc ctgtacctat tatattacca tctacatcat
    18901 aagcagttac tccatctggt agttttaact ttactacacc actataacct actaaggcta
    18961 cagcttctgt ttcataagta ccatcttcat ttttttcaaa gttaatctta gttaaaccat
    19021 tactcaaact aggttttcct gtatcatttg gctttaactc ttcacgacct gcttttaaca
    19081 atgcttctaa ataagctttt gtatttatcg ctacttcttt cctcttctga tactcagctc
    19141 tttcctcttc agtttttgct atttctataa gtttatcaca aaggtctata gagccttgat
    19201 actgcttaag tctttcttgt tcatctattt gtccaagaat aatccaaatt gcactttgag
    19261 tagctgagta agtcattatg tcattttctt cttcgcctaa attaaattgt tgcttatatc
    19321 caaatccatc aaattcagaa cctgcatata gtatagattt aactgcttct tcattttggt
    19381 tttcttgacc attaaaatct tctgctggta aatatggact ctttccatta ctacttggtg
    19441 gtcttaaatg attattgtaa caaaatgcag tttgctctcc atcttcacct tctattacat
    19501 atttgtcgtc ttttgagctt gctcctacaa gaccctttat tacatagtca aaagttaaag
    19561 tctttgtaat atcatcaaat cttaaatcat gataaggtct atctgaacca tctatttctt
    19621 ttagtaaaca agaatttttc acctttgctt ttttgtcata ccataagcta ataaatgagt
    19681 cttctgaagt aaaaacttgg ttaatttctg attgttcatc tgcctttaca tcttcttcat
    19741 cttcccaaaa gttatatact attttattta tttgagataa agtcatatca agaattttat
    19801 caatatcttg ttttaaactc atttcctcta taactatttc ttcttccaat ggtttttctt
    19861 cttctggaat ttgctcatct aatggtttct ccccatctgg catctgacca tctgatggtt
    19921 tctctacatc tggcgtctga ctatctgatg gcttctctcc atctggcatc tgaccatctg
    19981 atggtttctc cccatctggt atctgaccat ctgatggttt ctccccatct ggtatctgac
    20041 catctgatgg tttctctcca tctggtatct gaccatctga tggtttctct ccatctggta
    20101 tctgaccatc taatggtttc tccccatctg gtacctgacc gtctgatggt ttctctacat
    20161 ctggtgtctg accatttgat tgttcttctc cattaagtat tgtatcattg ctagtcactt
    20221 cgtcagcata agatactatt ggtgtaaatg cagtaaatac catactaaaa gcaattacta
    20281 aactgattat acttgatttt ttaatttttg ttttcaaaat tctcctgata ctaaaaacat
    20341 atattgtatt cacttaatat aattaaaatt attaaatatt atatgaatct tattcaataa
    20401 tacatcttta gtgtgttcaa ttagggtcgt tactcctaac cagttctcct atgaacttct
    20461 taatatttct attaagcaca gactatatca ttacctaacc ataaattagg tactccccat
    20521 ttccccacac ttgtaggtac gagatttctc tctagtcgtt gaagtttctt cttttcgaag
    20581 cttacctgct gattatccat tttcaaggca cttaggattt aaccttatgc tatctaacta
    20641 attttttcta ctttcgtaac ctcaagtgct tattaaatgc acactctatc acacttatcc
    20701 ttatttcatg attatgttgt ggtttagtta gctttaggaa cttccagcaa ttaaaggagt
    20761 tttgggcaga tatctgccac tctacactcg ttatgaatgc agggagcatt tcaaaaatat
    20821 atttatatct atcttctatt aattacttat ttatgtattt attttatata tttttgacaa
    20881 ttaaaagtta ctcctattta tatttatagc aggttgcact actaactcca tatatctttt
    20941 aagtgcccag gtttaagata tacttcacag tttctataaa taggtttttt aatttttctt
    21001 ttttaacttt ttaagtgcac ttttttaaca actcaataaa atataaatta gtatcctaga
    21061 tacttatcta ataaaagaca aaaattagtt tttataataa aaaagatact atagagtatc
    21121 ttcaaatatc acaaaaacct tttactctat cggatagttg acttaatata atatgcatat
    21181 taatacaaac cacatacttg agtatcatta tttttgtcca atattaattg taatagctat
    21241 tgttatcatt atacaatatc tagcatattt tgtctatttt ttccatttat tttacaatat
    21301 atattgccct caaaatacat taaaaaacat ctttagaagt aacttttaag ttttacttct
    21361 aaagatgtct aacttctatt tatctattat tttattttta atcttacgtc accttttatt
    21421 cttcttatta atgggtgatt aactgttctc attacatggt cagtaatatg atatacacct
    21481 aattttaatt ttggtgcaga acccattact gtgttactac agtcagtaca gtttcctatt
    21541 aatataactt ctgctccagc tttcttaaat tcaatacatt tttgagcttg tcctggacag
    21601 tgtcctggat tttcacattt taatgcacct ttaatttctt gagcttgttt acatttttga
    21661 actgatacta tatcagtaac tcccatttta gttgctatat ctctcattct ttcttcatta
    21721 ggtccacatg cacaaactaa aagacccatt tttctctttt cattaacaaa tggcatagta
    21781 actattatac caccactagt tttagttatt ggagcatcta aagtagtagc tttaccagtg
    21841 aaaggtcctc ctaggattat ttcaccatat tcacctttta ttccaccagc tctttcaatt
    21901 aattctccga cagttgttcc aattggcaca tcttcaaaca ctatagattc ttttccactg
    21961 tttaattgac caactacagt tatattttta gatataactg gtcttttttg ctcaacagcc
    22021 tctactattc tagttagtgt ttctacgttt attactactg cattagcctc tgaaggtaat
    22081 tgagttggct caagtaattt tcctagaacg tctcttacta ttgctctctc ttctcccatt
    22141 gggtacatat caactaattc tgcaacttct atgttgtctc ctggctttat tacttttttg
    22201 aaagcttcta ttgcttttgg atgcttactt tttattgcta gcataccttt tccagcatta
    22261 gtaacttcca tagcatattt tataccttga taaactattt ctggtctttc ttctatttct
    22321 tttatattat gagctaataa aggttcacat tcagctgcat ttgctaatat tgttccacca
    22381 tttaaatcta tgtttaattt tacatgagta gggaatcctg ctccacccat tcctactact
    22441 ccagcttctt taattaagtc aagtatacct tctcctttta atggttcaaa agtatcttct
    22501 tgtacttcat cagcttcaat tactatcgct tggtcattta tttcacttat ttttccacta
    22561 acactggcat aaatatttgc ccctaatcca gttggttctg cgattagagt tccttttttt
    22621 actacatctc caacacttac tactggctta tctggaccac caacgtgttg ttttaataaa
    22681 atagaatata gtttgttcaa ctagtacgcc cccttaagta tattaatttt tttataagct
    22741 gttcaaataa tgttaatgct atttttctat tataaggtct taacatattg tttatttcta
    22801 tagaacatat cgcttattaa caaagcaatt tctatgccaa cttttaaaca aacttatacc
    22861 ctttggaaat actgtcttac agcattcatt aattcttcta aatttttaaa cccatcaaaa
    22921 aaaagtcaat tattagacac ttttttaatc aatttaatct ataattattg atattgcata
    22981 catgtataaa aagtgtcaaa aaatagacac cgtcttttta tcgacacttt tctaacatat
    23041 actatataat ttatcacaac tttacttaaa atatacattt attacttatt aattcttagt
    23101 tttttgcact ccattggaat caactacata attatcttta tacaacaaat cagatatttt
    23161 gactagactg tatccatctt tttttagtcg acttattata gtatccaaat agttatctac
    23221 atcatttata ttagcatgga ataaaactat tgaaccaggt tgagattctt ttattacttt
    23281 ttcaattaca tgatttggtc caagctcctt ccagtctata gaatctacat cccacttaat
    23341 tactttataa cctaaatcac tacaaatgtc catagcttta ttgtttacgt ccccaaaagg
    23401 aggtctaaat aaattagtct tttttcctgt tatattatat attttttctg atgtagtttc
    23461 tatctctttt gttatgtctt cttttgatat ttccttcaaa ttggcatgag tgtttgaatg
    23521 atttccaatt tcatgtcctt tttcatctat agcttttaca atttcttcat tatcatccac
    23581 ccaactacca actaaaaaga aggtagcttt tacattatgt ttatctaaaa tttttaaaat
    23641 atcatccata ttatcagttc cccatgctac atcaaaactc aaagctattt ttttctcatt
    23701 tgtatcaact ttatatatag gcatttttga attgtcagat ttagaacata tgtattttat
    23761 tccataaaca aaaacaaata ttaacactaa taataatgaa aaaaataaaa cactatatat
    23821 caaagcttta gtccttttaa cttctctttt catactattc cccctttgaa ataatttctt
    23881 ctatatttaa aatttatttt ttttcagctc aaaaaagtac tgtaatattt aatttataag
    23941 acaataacta aaaaaataaa acctatattg acctaattaa actctctaaa atactcattt
    24001 atttaatttt tttatatttt ttacattttt acctttattt ttctgtatat attattttta
    24061 ttttggagaa attagtatta acatcacata aataaaagtg ttgttagaca tcataaacta
    24121 attatttgag gaggaaattt actatgtcaa attcaaacag aacagtagtt ccagaagcaa
    24181 aagctgcttt aaaccaaatg aaattagaaa tagctaatga aataggttta tctaactatg
    24241 aaaacataga caaaggtaac ttaacagcta gagaaaatgg atatgttggt ggatatatga
    24301 ctaagaaatt agttgaaatg gctgaaagac aaatggctgg aaaataaata gtaaattttg
    24361 acacctgggt atcaacaggg ctgctaatta gcagccctgt ttctctatat ttatttataa
    24421 aattgttttt atatgaatta ttaaagatta ataatacaat acaaattgtt cttttaattt
    24481 tgtacaaatt agtttaatat attatatata gaaatagttt gacggaggat gatatttatg
    24541 tttgaaaact cgtctgaaga attagcctat cacaaacttt taattttata tatattagaa
    24601 aaaattaaaa tggatttaac taattctcaa ataactcaag tagtattaga gactgagatg
    24661 atgaattatt tttcattaca acagctttta tctcagctta tggaatctaa gtttttgact
    24721 acatataaag actctgacag agaatattat gctcttactc aaagaggcgt agaaagtcta
    24781 gaatacttct ttaatcgaat acctactagt gttactgaaa aaatagacaa gtatatagat
    24841 tctaacaaag aaaatctact agcagatact caagtaaagt ctagttttgt aaaacaaagt
    24901 gataatgaat ttattgtcaa ccttagagtc atagaaaatc agtctaactt aatagattta
    24961 aatctaaatg tttcatcaga gaaacaagca aaacttattt gcaataactg gaaaaataat
    25021 gcatcttata tgtatgccga agttatcgat ttacttataa gagacataca ttaaagccta
    25081 caaacaaatt atagttgtag gctcttttcc taccttgatt tcttttatta atttgttatt
    25141 tgcagtttca taaactttta ctgaattttc ttgtgtatct gatacaaata gtaacttttc
    25201 atctttagat atttctaatc cttggggaat cccatttatt tcaatatttc caatgtatct
    25261 actcgttgta taatctaaaa ttcttacatt attataaccc aaatcagcaa cataaacttt
    25321 tttgccacta taattaaatc ttatttctac tggtaataaa aattcatata ataccttttt
    25381 tatatccatg cttacttcat ctattattat aagctttcca tcaagtgttg atatatacat
    25441 ttctttcttt tgtttatcaa gttctatatg ccaagctcta aagtccatat ttattttctt
    25501 ttgtatattt ttattaattg tatctataca tactatcgag tttatacacg gtacatataa
    25561 ctttttgctt tctctatcaa agtcaaatcc atgtggcata ttatcaactc caataattcc
    25621 tattggattt aatgtgtttt tatctagtac atatatacta ttagaatctt catttgccac
    25681 aaacaattca ttatcgctaa gtacaacttg actaagactt cctcctatag agacagtatc
    25741 aattatttta tcattactta aatctaagac atagagtatc ccattacttg aactaggtat
    25801 gtatattaaa tttttttctt tttctatgca aaaatggtgt ggatatatat tatcttctaa
    25861 tactatttct ttttctagtt caagtgtaga ataatcaact atgctaatac tctttgataa
    25921 gtagttagaa atatagattt tcatataacc cctcctctct acaatacata tactacaata
    25981 atatattatt tcattagctt gtattatgct ttatagttgc attattacgc atatatttgg
    26041 tattattatt aatgttaaaa aaagaaataa tatttaatgg aggtcttttt aatgaaagta
    26101 acatttaatc caagtggtgt atgttgtaga gaaatgattt ttgaagttga tgaaaataat
    26161 gtgattgttg atgctgagtt tataggagga tgtaatggta atttatcagg acttagaagc
    26221 ttaataattg gccaaaatgc tcttgaagtt gctgataaat taaatggtat tgactgtggt
    26281 ggaaaaggta cttcttgccc agaccaatta tctaaagcta tacgtcaatc tatataatta
    26341 cttatataaa catcagtaaa attattaaaa acttatttta tataaaaaga gttgtccatt
    26401 ttttagacaa ctctttttta tatttttatt tgtatactta ttttataaaa ttataatttc
    26461 tttactaaag ttctcactgt accaatcata tataatgaac ctgcacttat tataatatca
    26521 tcctcacttg atgtttctaa tgtataattt actgcatcct ctatctcatg ctttgatgtt
    26581 acatcatcta catattttaa tactttttct cttaatatat ctgaatttat ggcccttggg
    26641 ttatttggtg ttgttgttat taccttatta aaatgtggca acaatatctc taaaacacta
    26701 tcaatatctt tatcttctaa catacctatt aataaggtta attttctacc tttaaaattc
    26761 ttatcaagtg cttttgccaa agattttgct ccatcttcat tatgtgcacc atctattata
    26821 aaaattggat tttcttttat cttttctatt cttcctggcc atttagtatt tataagtcct
    26881 tttcttatag attcttcatt tatatttgct aatttattta tgtcttttag atattttatt
    26941 acactaattg ccaagataga attgtttatt tgatgttcgc ctatcaattt tatttcaagg
    27001 tctctataag tttctttcat tacagtacaa tcgtatattt gagaatttat atctgatttt
    27061 tttatgttta tatcatcaaa atcaacttct atatatttag cttttttctc tttacaaact
    27121 gactttataa catcctttgc ttcatcagtc tggtcatata ctagtactac tccattttcc
    27181 tttattattc cagccttttc gtacgctatt ttttctattg tatctccaag tatacctgta
    27241 tggtccaaac ttatagatac tatcacactt acaagtgatt ttgttattat atttgtagca
    27301 tcatatctgc cacctaaacc aacttctaat gccacaaagt ctaccttttg ttctgaatag
    27361 taataaaacg ccattgcagt aaccacttca aattctgtcg gatatgcata gccttctttt
    27421 accataatct ctattttttc ttttattaac tcaattattc tagcaacatc atcctgtggt
    27481 atattttgtc catttactct tatacgctca gtaaaagttt ctaaatatgg agatgtatat
    27541 aaaccaactt tatatccaca ctctcttagt atattagaaa caaaagaaca cacagaacct
    27601 tttccattag ttccagctac atgtattata ttcaaagttt cttgtggatt tcctaataat
    27661 tctaataact ttccgatatt ttctaatcct aatcttatac cgaatttatt agtttgtgat
    27721 atgtactcta atgcttcttc atatttcatt atctaactcc ccctgtattg gcattttctc
    27781 ttatgctatc taattatagt atatttttta cttttaatct accgacaaag aatacatata
    27841 atttaatacc ttctacatta aatttagcta caaatcttta tttataagtt tttatatctt
    27901 tccactaatt cagtcagtgt atatattgaa actaagtcat attttgagat gtccatataa
    27961 ttaaacttta tgtcaaatct atgctctagc tttttcaaca gattaaaaca attatcataa
    28021 accaagccta tctccttatt aaaaaggcta cccttaaaga gtttttcatt attctcttca
    28081 atatctaagc aatccctaac aacgtcagca actttcataa aaagagcatt ttctttgtca
    28141 tacaaatcca atttaaagtt tacaattcta ctacactcat caaaatcaca actatcccaa
    28201 tgatttctag ttgctaatga ttcaagctta tcatttaaat cagatattgt tatgcctggt
    28261 ttttctgata atatcttagc tattttacca gtaagctttg ctgataaata actattacat
    28321 tttggtggta atctatagga attatttata tcacaactta tatatgaatt gctatccata
    28381 acacattgaa catcatattt tttgttgtac caaaatgaat catctccatc taaagtaaat
    28441 cctcttacac ctataacatt gttaaacata gctggataac ttaagtcaaa atcattagcg
    28501 agtgaacata ctattatttt tccttttcta aacaattcat agcaaacttc aaataagccc
    28561 ttaacacttt ctactcctat gactgataaa cttaaattaa ttaatcttat gttagtgtct
    28621 aaaaggtatc ttaatgcttc ttcaagaact tttatatttg taataccatc ttttctcaaa
    28681 atttttatta caaataactc tacatcttca tactctttct ttattattga tgcacaagca
    28741 gttccatgac catcttcatc atcaaattta tctgatataa agatataatc atgcatacat
    28801 tcaaaagcaa ttcctccaac taaattatct tttaagtaat catgttcttt gtctattcct
    28861 gtatctaata ctgcaacctt aactttatta ttcatatcac atatattctc cattacaaaa
    28921 gtttttaata tatctatgtt aatagttcat cttaaacttt gatttaagtt gcacaattta
    28981 tcttttaaat gctatatttc ttgctaaaaa cataaaataa gtacaccata tatttaattt
    29041 atatttatta tatcaattat tatcattaaa tggttaaatg ttaagataaa atttttagat
    29101 ttatatcaca atttagaatt atttgtaaaa aaggagatta tctttttatt agacaatccc
    29161 cttgtatatt ttattaatat ttatctatga ttaagcatca attttatttt atactttttg
    29221 attttaatac tatacatcta aatcttattt agggggaaca attatttata tgatataaaa
    29281 atgctaattt gaatgaactt gtcttataat cagttttaga aaatacacca ttctacaaag
    29341 tatgaatcaa aaggtgaaaa aatactaaaa ataataaatc aacatcaatt ttaatcaata
    29401 tatgaaaaac ttataccaag tatgtataaa aactaatata aatattattt taacaactaa
    29461 tacttacacc tttatatatt atatcatatt tcaataaata aattgcataa aaggaaatct
    29521 tttcatagaa ttaaactatt tattaattca ttactatagg ttcaataaac tataagatgt
    29581 cgctttaata tttatattgt actccattaa atattaatat aattaattaa agtatgcgta
    29641 gctaaatgaa acaaatatct atagagtttt ataaatagtc attattttaa aaaggtaatc
    29701 atattctaaa aatacatata atgcatataa aaatcaataa tagtatattg ataatcaagc
    29761 tactaattaa taatcatgct actataatgg aaactctaaa tatacatatt aaaccatatt
    29821 aaaagtctat aaactgctat tttgcataat aaaactgtct taatataaat aacattttat
    29881 atattaagac agtttcaatt aatagccctg tgatgacatt aaatcttttt tacgatattt
    29941 tcaattacct ttttaaaatt aatacattat atcacataac aagcttgtta atgctacttt
    30001 taaatcttta agtctatact tacttatagg tataaattgt tcattaatag taatcatatt
    30061 atccctaaga tcttctattc ttcttaaatt aacaataaaa cttgtatgac atctaaaaaa
    30121 gccattttca cacagtaatt tttctgcttg tttcatgctc atattagctt tataatctct
    30181 acctattgta tgtacgacta aatctctctt tacagtttca acatataaaa tagaatctat
    30241 cagtattcta ttaaatcctt ttttactatt taaaactata taacgctcct tctttctttg
    30301 aaggttatca atacaaagat ttacacccat tgcaaagtta ctatactcta taggctttac
    30361 taaatatcta taagcacgaa cctcataacc ttggggggca tactctgaaa aagccgttgt
    30421 aaatataatt tctacttttt catcaaactt tcttattttt ttagccacct caattccatt
    30481 gatatctttc atttggatat ctaaaaatat aatatcaatt ttttctgggt atttggatat
    30541 taaatcttct ccacaggaaa attccagtat ttgataattt agacatcttt cagacaaaag
    30601 tttttctgta aactctttta gtatgcttct ttgtattttt tcgtcatcac atataactac
    30661 cctgaacata atatcacctc caaatctaaa atatcattta gtttacttta tttcaatttc
    30721 caaactgtac tcactagctt tcaaatttaa atttctttat aaatttaaat tgtcgattaa
    30781 actacttata gaaattctct ttaatattta aacttaaatt acgataaatt cctatacttt
    30841 tctagatata ttatgtaaaa aaatatagta aaataaatat aatatgt
//
LOCUS       DAMKNB010000040        30674 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.042, whole genome shotgun sequence.
ACCESSION   DAMKNB010000040 DAMKNB010000000
VERSION     DAMKNB010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 30674)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30674)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30674
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.042"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            149..2050
                     /locus_tag="PC494_002078"
     CDS             149..2050
                     /locus_tag="PC494_002078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HDF3912578.1"
                     /translation="MRERIILETLKNSSGYLNIDYFADKLGVSTRTIRNEIKKIETIK
                     ECNGFKLEYKSKLGYILNIKDQDKFEHYLRNLPSDLVENPEQRLESIIVELLVNEGYK
                     TIEQLSKKFLVSSSQIKNDLKKIDEKIKDTELKLERKAHYGIKIEGSIKEIQSILVDS
                     YFRGNRNITEYRNKFIDNLKLANIRSTIKNVLNEHDLEANLTELEEILAQIIILYIRV
                     SMRVVGNASDLKLYTEDLIIDKLLDKIFRDKKYNLNYDEKYYLKELIKLKTKDKKATI
                     KNIDKNKLQDIMFEFFREIDKKYNSNFLEDKEFFNLFYLHIACLIERIKKNHKIINPF
                     SVKISQQYPTVFNLSIQFSKIIENEYHIKISQDEIGFIATHIAVPFEKREEANFNKKY
                     KIAIICSSGGGSAFLINLRLKEIFPNAEIRNFSLLEEKAVIEFAPDLIFSITNLLFEI
                     NAPVILINEILDELDYLDIKESVRFADHIGNISSPKQYILGLFDKNHFRCIKDKAKYK
                     DILDSMSKCIVDEGACSPTYPKDVWERESYLSTIYTNGVAIPHPIEMTGNKNIISVAL
                     IQTDIIYENRVPKIIFMISLIKGNLELHKQISKYLSKIMANKDMVDMLNKSQSYEEFM
                     YKLKIYLGG"
     gene            2053..3096
                     /gene="ypdE"
                     /locus_tag="PC494_002079"
     CDS             2053..3096
                     /gene="ypdE"
                     /locus_tag="PC494_002079"
                     /EC_number="3.4.11.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HDF3912579.1"
                     /translation="MNIEFFKRLSEADGIASNEEEVRHVLLEELKAYSDKIICDGLGS
                     IIFSKIKDESAPNVMICAHMDEVGFMVRSIDKLGMIHLITIGGVKPLAQFVQKVRITT
                     KEGKKIPAVINATYNNGKAENIYADIGAYTEEDVYNLGINVGDMVTYTTSFEEFTLPD
                     RLVGKAFDDRIGCFVMGEVLKELRKENLNCNIHFAATSSEEVGIRGAKTSTQLINPDI
                     VFVIDVACAKNEFVRDYTNKKQIDKGVMLMHRDRTLVPSRKMIDYVMEIADKNNIPLQ
                     HDMFESGGTDGGEAHLVNEGKPCVVTCVPVRYGHCAFSIVSNKDLENIIRLYTQLILN
                     FDEEQYKHIRNFI"
     gene            3111..3416
                     /locus_tag="PC494_002080"
     CDS             3111..3416
                     /locus_tag="PC494_002080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HDF3912580.1"
                     /translation="MSTEVQIMELISTAGESKSKAFEALKKVKSKDFKGAKLLIEEAR
                     KIDIEAHRIQTELITQDLNEDVESPAMSLLMVHAQDHYMTSQLAKDLIEALIYCLDK"
     gene            3513..3848
                     /locus_tag="PC494_002081"
     CDS             3513..3848
                     /locus_tag="PC494_002081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDF3912581.1"
                     /translation="MKILLCCAGGFSTNMLMQNMKKVVKESAKLNEKDFEFTAIPADS
                     IESEVDDWDIVLIGPQIAHKIDFLKGILEPKNKPFAVIDKDVYGKMDGATVMKLALIT
                     YKKHQLAQG"
     gene            3880..5202
                     /locus_tag="PC494_002082"
     CDS             3880..5202
                     /locus_tag="PC494_002082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDF3912582.1"
                     /translation="MFSKFEAFMNRVFMPLAHKVDNQRHLGSIKAGMVAMTPFTILGS
                     IFAILPALPNMLGENNPISKFILSNSAILDLPVSLSIGLIGLYACMCIAFNLGNYYKL
                     YIPGCVALSTFSFLFLVASFTPDGALEIGNLGAKGLFTGMIAGLGSVELYNFCNKKNI
                     TIKMPENVPDFVSRSFELIPTTIIVCGTFIVARFISLKVFGELPPQILTQFLSPLVGS
                     MDNPWSVLALNFAICTIFFFGIHSSVFSPITRPIMITFIAENIAAMQAGETIPHFFTA
                     GASSAFFGFTGCGISIGCVIACMLSKNASYKKIGRVSLFPALFGINEPILFGAPIILN
                     PIMFIPHVFGGAIIGTLPMFFMHWGWLAKPVFDPPYVGVFLEGFLTNGDWHSILANAL
                     QLVLAVLLYWPFFKIMERQQNNKKQKEETKNIFSKEEEDLLDDLGLDF"
     gene            5212..6282
                     /locus_tag="PC494_002083"
     CDS             5212..6282
                     /locus_tag="PC494_002083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HDF3912583.1"
                     /translation="MNNTMERLVSLIYKRGVDALLIKAKNTKRYIGALSGSGVYVLVT
                     KDKNYQILDGRYIDEADKKTTGFIKRIVSQGSYIPTIIELLKELNIKKLAIENQAMSI
                     QEYLSLKNEGFEINLITNELWKLRAIKSKEEIKLIKKACEITDEVFDEVISEIKKDMT
                     ELEVSALIQYHALKKGASGMSFETIVVSGERGAMPHGRPTNKKLKVNEAITIDFGVVY
                     QGYQSDMTRTISIGKPPKIIKEIYDVVLEAQLSAIESIKEGTRASDVDKVARKIIDKH
                     GFGEYFNHGLGHGIGLGDGEVPTLNPNSEDILVEGMVMSCEPGIYIPNVGGVRIEDDI
                     VIIDGKGVPLNKTSKEFIILGE"
     gene            6287..7474
                     /locus_tag="PC494_002084"
     CDS             6287..7474
                     /locus_tag="PC494_002084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HDF3912584.1"
                     /translation="MKYNFNKVLNRKEGNCRKWSNHVIKEKFGLNEDAIPMDLADIDF
                     ECAPAIKESILKRASVGDYSYTFIGDDFYDAIINWNKRRFDVYIEKDWIKLTFGTVST
                     LHYIVQAYTKEGEGVLINTPAYDPFAEAVVNNNRKLCCSSLKLDNNRYYLDLEDMENQ
                     MKYENIRLLIFCSPQNPSGRIWTKEELYQVSELCLKYNVILVSDEIHRDIIFKDYRFV
                     SLWNAHPEIYKNSIICVSPNKGFNLGGLKTSYVLIRDVKIRETLLERLKSNSITSPNV
                     FAIPAIVAAYNESEEWLDAMTSYVEENFEIVYDFFETNIPKAKVMKSDSSFLAWIDVR
                     EVFRNEEESKEFFRHANLTMVVGSYFVKDGDGFIRINVGCPRETLNEALNRIKKTYIS
                     MYC"
     gene            complement(7671..8543)
                     /locus_tag="PC494_002085"
     CDS             complement(7671..8543)
                     /locus_tag="PC494_002085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase family protein"
                     /protein_id="HDF3912585.1"
                     /translation="MNILQNENLIIESSSFGAELTKIFSKKYDKNILWDGNKKYWGRQ
                     SPILFPIVGKLFDNETIIEENLYSMTQHGFARDMDFEIVDKGDTFVTYKLTDNESTLK
                     KYPYSFELIINYTLNDNSIEVEWIVKNTDSKDIFFSIGGHPAFNLPFYEQNDFSKHYL
                     EFKSKNDVEKINLNGSFTDDIIPIGKLKNLQLNPEVFKNDALIYTNIDEVSICNNDGS
                     KYVTISMEDFPLVGIWTPYYSETNSTAPFLCIEPWYGLADSINSNKIYKDKKFINKLS
                     KGKVFTASYNINIH"
     gene            complement(8937..9128)
                     /locus_tag="PC494_002086"
     CDS             complement(8937..9128)
                     /locus_tag="PC494_002086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3912586.1"
                     /translation="MDDFSKLKSLYEDGYRCIYHDCVDNNYTIYLKNFYTEGSETIEL
                     SSESDFSQFKDYIDGLRMS"
     gene            9348..10394
                     /gene="cobT"
                     /locus_tag="PC494_002087"
     CDS             9348..10394
                     /gene="cobT"
                     /locus_tag="PC494_002087"
                     /EC_number="2.4.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide--dimethylbenzimidazole
                     phosphoribosyltransferase"
                     /protein_id="HDF3912587.1"
                     /translation="MSLLESISKNIYSLDNSSIEKTKQRLDRLIHPTGSLGKIEDICM
                     QLAGIFGNENFDTSKKVIIAFAGDHGVYEEGVAPDPQNITKLQFPNFSKGLCGVGVIS
                     KFVGADVVAVDVGINCDEKLDGVLDYKIRKGTSNMAKGPAMSKQEAIRCLEIGIEIAE
                     QCIEKDYKVIGIGEMGIANTTPSTAIISVISGCDPLEVTGIGAGLKKERLKHKAEVIR
                     KAIEINNPNPTDGVDILSKVGGFEIGSMAGVILGCSANRIPVVIDGFISYAAALIAYK
                     INPKTREYMIASHLSAESGTKRALDILKLDPLLNMDMRLGEGSGAALAFDIIEASNYT
                     YKNMATFDEIDMGR"
     gene            10426..10986
                     /gene="cobU"
                     /locus_tag="PC494_002088"
     CDS             10426..10986
                     /gene="cobU"
                     /locus_tag="PC494_002088"
                     /EC_number="2.7.1.156"
                     /EC_number="2.7.7.62"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional adenosylcobinamide
                     kinase/adenosylcobinamide-phosphate guanylyltransferase"
                     /protein_id="HDF3912588.1"
                     /translation="MSKIILVTGGARSGKSNFAEKLCFDRNNNTAYIATSIPFDDEMK
                     DRVKKHQENRPRNWNTYEIYEDIYSIIKEIYKEHETVILDCVTLLVNNLMFEHNLNIE
                     ESSQEEINKLEQYIKEQVVKLIEEIEKTNLYFVFVTNELGMGIVPGNKLSRIYADIVG
                     RINQYIASKSNEVYFVVSGIAMKIKE"
     gene            10996..11769
                     /gene="cobS"
                     /locus_tag="PC494_002089"
     CDS             10996..11769
                     /gene="cobS"
                     /locus_tag="PC494_002089"
                     /EC_number="2.7.8.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosylcobinamide-GDP ribazoletransferase"
                     /protein_id="HDF3912589.1"
                     /translation="MKRFILILQFLTRIPIKLNVGFDDEFYKSIVYFPLVGFVIGILS
                     YLIGWISMLLFEPFIASIIITLAGVLITGGLHIDGLGDTFDAIYSYRDKEKMLEIMKD
                     SRLGTNSLLAIMFVLLLKVGFVYDIISNNSLWVIIFMPMIARLGVMLLTYKTVTPREK
                     GMGNLFIGKLTTSMLITAIIYTLLIVALITKFIFLLPNIVLIKVLGSIIVVFVFIILF
                     KKHIYKKIDGVTGDILGCGIELSELVYLIYIYLLIFMFF"
     gene            11789..12403
                     /locus_tag="PC494_002090"
     CDS             11789..12403
                     /locus_tag="PC494_002090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HDF3912590.1"
                     /translation="MIRLILIRHALTNDNKKGRLSGHINSCISEEGKLQINKITRYLS
                     NENIDKVYTTPSTRTKDTVEKISKLKLLEIEEKEALREISFGDFEGRTFEEIKIKYPN
                     EFEKMIKEGNNYRYPNGESLIDSYKRVAKEIDNIILENNSNLDTKTILICSHAGTIRN
                     IITHLISGSYKYHWNFKIDNASITVLEIDGGFAVIDKMNFTDFI"
     regulatory      12470..12649
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00174"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cobalamin riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="adenosylcobalamin"
                     /db_xref="RFAM:RF00174"
     gene            12779..14278
                     /locus_tag="PC494_002091"
     CDS             12779..14278
                     /locus_tag="PC494_002091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobyric acid synthase"
                     /protein_id="HDF3912591.1"
                     /translation="MLQGTASNVGKSVLVAGLCRIFKQDGYTVAPFKSQNMALNSFIT
                     KEGLEMGRAQVFQAEAAKIEPIADMNPVLLKPSGNNKSQVIVRGKVVGEMPSSKYHDY
                     KLELVDVLKETFNSLNSRYDIVVMEGAGSNAEINLKDRDISNMGMAEIADAPVIIVGD
                     IDRGGVFASLAGTMLLLNEDEKRRVKGVIINKFRGKKELLQDGVKMLEDIIKVPVIGV
                     VPYTDIKIEDEDSVTTRFKKKMNKSDIHIEIIRTPHMSNFTDFNIFETQEDVSIRYVD
                     YGESLGNPDILIIPGTKSTIDDLTYIRKSGLESQIKNLHSQGKLIFGICGGYQMLGKK
                     LKDPYHVESEIEEVDGIGLLDTETTFEKEKTTTQVEATIVECISEYMNNLKGKKVKGY
                     EIHMGITKRGNDVRSLDLITKKLDKEVNYTEGSVNKEGNVIGTYLHGIFDEISFTRAI
                     LNNIRKKKGLGELESKVNSFNEFKDKEYDKLADFLREHLDIEKIYEIMK"
     gene            14317..15693
                     /locus_tag="PC494_002092"
     CDS             14317..15693
                     /locus_tag="PC494_002092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobyrinate a,c-diamide synthase"
                     /protein_id="HDF3912592.1"
                     /translation="MKKILIAGTNSGVGKTTISLGIMQALVKRNMKVQPYKVGPDYID
                     PSYHTFITGRHSRNLDSYMLDDEKIKYIVNKSSKDADISVIEGVMGLYDGFGIDLDNC
                     TSSHTSKVLKSPVILVINGKSMAASSAAMVLGYKELDKDVNIKGVIVNNVKTNSHYQI
                     IKSSIEKYCNVEVLGYFPPNNKFSLESRHLGLVPSVEMKSLREKFYTLADEIEHYIDI
                     DRIIEISESDEFESDFDFQTLIENNKIKEHVNNKSIAIAYDKAFNFYYRENIELLEEL
                     GLEINYFSPLEDASVPNADYIYIGGGFPEIFGKELEANESMRTSILEAHNNNIPIYAE
                     CGGLMYLGEKLLNQEEQEFNMVGIFSGISKMTSSLKRFGYCIGVAKENTLLSKKGESI
                     KGHEFHHSIFESDEKCVYSMRKERDGNIVEEWDGGYSKGNTLATYLHTHFYNNLNCIE
                     NFLKKGNE"
     gene            15694..16665
                     /locus_tag="PC494_002093"
     CDS             15694..16665
                     /locus_tag="PC494_002093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalamin biosynthesis protein"
                     /protein_id="HDF3912593.1"
                     /translation="MSILSIYIGYVTDLIVGDPYSFPHPVRFIGKLINFTQCIIRKVS
                     KNDRQLKFGGFILWLITVGITYLTTYAIVKLFSFNILLSIVVNSFIIYTTLATKCLKD
                     EALKIYNVLKTEDIEKSRIQLSYIVGRDTTNLSEPEIIRATVETVAENTVDGIIAPMF
                     YAFIGGAPLAMAYKAINTLDSTVGYKNKKYKDIGFASAKIDDIANYIPARISVILMTI
                     GSFFLNYNYRNCFKISIRDRKNHKSPNCAFSEGAVSGALGIQLGGTNVYFGEKVYKPT
                     IGDKLREIDKEDIIKTNKIMYASSFVSMLVFTLIYVLCRMILINLII"
     gene            16697..17767
                     /locus_tag="PC494_002094"
     CDS             16697..17767
                     /locus_tag="PC494_002094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HDF3912594.1"
                     /translation="MKDLGHGANVDEMARLYGKNPKEIIDFSSNINPNVLPNLERYIL
                     KGLEECRNYPDINYTNLRENISKYIDINPDFIIPGNGATEVIYLLMKSIKKKLAIINP
                     TFSEYRRSAELNNLDIIDLELDLENNFKLNIDIIKENIKRFDSLFICNPNNPSGNVQD
                     LKELVHLLDKHNKVLIIDETFMEFVEDESKYSLVKYIESNKNIFIIKAVTKFFGMPGL
                     RLGYGLTSNTEIMNKIYEHKEPWTINSFADILSNFIFEDKEYIKNSKEYYIEERKYML
                     QELRNIRNIKVYDTDANFILIRIYKKTTKELKKDLFKQGNILVRDASNFIGLDDSFIR
                     VAIKSHEDNKILIENMKNLLGD"
     gene            17769..18656
                     /locus_tag="PC494_002095"
     CDS             17769..18656
                     /locus_tag="PC494_002095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalamin biosynthesis protein"
                     /protein_id="HDF3912595.1"
                     /translation="MKSYGICPASCGEFVQGIIDDEEYLCSYAIDMYSKVYIEEKLVD
                     INLGRYKSRLAIEKVFEKFNLPKKYTKNISLNINSKIPVGKGMASSTADIGATIKATL
                     SLIDKDLSSEEISKLAAEIEPTDSIFIDKNSIFNPLNGTVIKYLGNLTNAKVVILEPN
                     KVLDTMKIRLRQDYNKLKVENKEVIKKSFALLEEGLKKNNLSLVGEACTLSSLANENI
                     EKKECLNEIIKISKKYGAYGVNIAHSGTVVGILIDKSMNDKKMIDALCESNINSVYNK
                     IYTQNIINGGIKGEIEWNT"
     gene            18644..19276
                     /locus_tag="PC494_002096"
     CDS             18644..19276
                     /locus_tag="PC494_002096"
                     /EC_number="5.4.99.60"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003724727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt-precorrin-8 methylmutase"
                     /protein_id="HDF3912596.1"
                     /translation="MEYIKNPMKIEEKSFELIQEIIDEIRPDYKFKNNIEEKIIKRAI
                     HTTADFDYLDILKISEEAVDSIIDALKNNASIYTDTNMALSGINKRKLESLGCKYKCL
                     VADDETVKLAKEKGITRSMAAVEIAAKEEGRKIFVLGNAPTALYKVMEMKSEGRLDLD
                     AVIGVPVGFVGAQESKDEVEKTDIPYIISKGRKGGSNLAAAIVNAILYTM"
     gene            19285..20511
                     /locus_tag="PC494_002097"
     CDS             19285..20511
                     /locus_tag="PC494_002097"
                     /EC_number="2.1.1.195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt-precorrin-5B (C(1))-methyltransferase"
                     /protein_id="HDF3912597.1"
                     /translation="MEEYVYIDGKKYRRGYTTGSCATGASKAAVYMLITKNRINTINI
                     DTPKGIPLLLKVDNINISDTFVECSIKKDGGDDIDATHTMDIYARAEIVAKNDKNKGY
                     LTLKDIDSLSTNSECKSELYKFIRVYGGTGIGVVTKKGLSVDVGKPAINPTPLKMINH
                     EIRKLIGDNFESILGNDKVLKITIFAPQGETVAKKTFNPRLGIVGGISIIGTTGIVEP
                     MSDEGWKKSLSIELQMKKEQGLDKIILVPGNHGEQFIREKLNLDIKYVVRVSNFIGYM
                     IKEAQRIGYKKILMAGHIGKFIKVSAGIFNTHSKVADARSEILVANLALMGARYEFLN
                     KINQCVTTEEAVELINNSEYREVYNILSNKCRERVKQYLNEDSDDIDVEVIIFSMDKS
                     LLGKSDNTDDLVEVFI"
     gene            20508..21116
                     /locus_tag="PC494_002098"
     CDS             20508..21116
                     /locus_tag="PC494_002098"
                     /EC_number="2.1.1.289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt-precorrin-7 (C(5))-methyltransferase"
                     /protein_id="HDF3912598.1"
                     /translation="MINIIGLGPGNLDYITKKGENLISTSDVLIGGKRNLESIKNFEG
                     EKIVLDSNLREIIEYINNNKEKQISIIASGDPLIYGIGRYLSKNIDNKMLNMVSGISS
                     LQYIFSKIYVDMNDVYITSSHGKVPDFDYILSHKKVCMVTDSKIGPKQISREIIDRNL
                     NKIIVVGENLSYDNEKITIAKPEEIIRIDNFDMNVVVILDEE"
     gene            21106..21681
                     /locus_tag="PC494_002099"
     CDS             21106..21681
                     /locus_tag="PC494_002099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="decarboxylating cobalt-precorrin-6B
                     (C(15))-methyltransferase"
                     /protein_id="HDF3912599.1"
                     /translation="MRNSEFITGKVPITKEEVRAISISKLNLVNAKNLIDIGAGTGSV
                     SVEAAYNYPNLKVISIEKNDDAIELIEKNIKKFNLKNIEVIKGCAPINLGLNVKVESI
                     FLGGTGNNLEEIIEWSKKNLVTGGRLVANFIIIDTFNQTLKLLKKHGFKEIDVCVLNV
                     SKLEKLGKGEYFKPLNPIYIISCEKGENDDE"
     gene            21674..22426
                     /locus_tag="PC494_002100"
     CDS             21674..22426
                     /locus_tag="PC494_002100"
                     /EC_number="2.1.1.271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt-precorrin-4 methyltransferase"
                     /protein_id="HDF3912600.1"
                     /translation="MNKVHFVGAGPGDKELITLKGYKLLSNADVVIYAGSLVNPELLE
                     YCKEDCQIHNSAHMDLQEIIDVMREGIENNKSVVRLQTGDFSIYGSIREQVEDLNKLN
                     IDYDCTPGVSSFLGAASSLGVEYTVPEISQSVIITRMEGRTPVPEKESIQSYAKHQTS
                     MVIFLSVQEIEKVVSKLLEGGYPKDTPIAVIYKATWADEKIVKGTLSDIAVKVKENNI
                     NKTALIMVGRFLGEEYNNSKLYDKDFKHEYRG"
     gene            22410..23531
                     /gene="cbiG"
                     /locus_tag="PC494_002101"
     CDS             22410..23531
                     /gene="cbiG"
                     /locus_tag="PC494_002101"
                     /EC_number="3.7.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt-precorrin 5A hydrolase"
                     /protein_id="HDF3912601.1"
                     /translation="MNIEGNIAIICITENGKKLALKINSLVNNCVIYQVKNKKSNLVV
                     EETCVHTVQKKLSDFVGEIFSKFDYIVFIMATGIVVRSIAPYIISKFSDPAILVMDEK
                     GKNVISLLSGHIGGANSLTQYISSLIDANPVITTATDINQKASLDMIAKKLNAHIDNF
                     RESVKEVNSMLVNNKCVGLYVDEGYQVDTRGFKLIESKDELRDSFSNTYIEKLVVVSN
                     KINCIEDIENLNLDNKFEHCYSTQKIIKVIPRDIVIGIGCRRNTDSELMYNSLEEFLN
                     KQNIDIRAINTVGSIELKKDEKAIIELSKILKVPFKTFSVDEISKVDNLFDKSDFVKK
                     NVGVYSVAEPVAYLLSKGNLLVEKHKYKGITFSVGRIKI"
     gene            23528..24253
                     /gene="cobJ"
                     /locus_tag="PC494_002102"
     CDS             23528..24253
                     /gene="cobJ"
                     /locus_tag="PC494_002102"
                     /EC_number="2.1.1.131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011701973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="precorrin-3B C(17)-methyltransferase"
                     /protein_id="HDF3912602.1"
                     /translation="MIYVVGIGPGSKDTMTLEAIKAIEDSEAIVGYKTYIKLIEEFIQ
                     GKEIIQNGMRQEVDRCKQAVEEAKKGKKVAVVSSGDAGIYGMAGLILELISKEDEDIK
                     VKVIPGVTASIGAAAILGAPIMHDFCHISLSDLMTPWEVIEKRLRLAAEADFVICLYN
                     PRSKGRSEHLSKAFKIMGEFKGGDTPVGVVKDVGREKEEKFVCTFENMDFEKVDMTTM
                     VIIGNKSTYINGELMITPRGYTV"
     gene            24250..25002
                     /gene="cobK"
                     /locus_tag="PC494_002103"
     CDS             24250..25002
                     /gene="cobK"
                     /locus_tag="PC494_002103"
                     /EC_number="1.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="precorrin-6A reductase"
                     /protein_id="HDF3912603.1"
                     /translation="MILILGGTSDSLSICDKINELKNQPYILSVTTDYGRELAQQHAE
                     NVILGKLGKEDMLKFIKDNNIVKIIDATHPYAVEVSKTAITCAKLLNIDYIRFERKSL
                     IEEIDYDNKFIVDTIEEACEIANKIGTNIFIGTGSKNLNRFIEEISDKNLVVRVLPTS
                     EVILSCEKLGLSADNIVAMKGPFSQYINEETYKHYNIDLVITKESGIAGGFLEKVNAC
                     KTFNIPVIIIKRESINYENVFNDINKIKDILV"
     gene            25021..26499
                     /locus_tag="PC494_002104"
     CDS             25021..26499
                     /locus_tag="PC494_002104"
                     /EC_number="2.1.1.151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt-factor II C(20)-methyltransferase"
                     /protein_id="HDF3912604.1"
                     /translation="MKKALLVVSFGTSYHETREKTIDICEDKIKNSLKSHDFFRAYTS
                     NMIINKIKKRDGIEIDNPIQALDKIYEQGYDEVIIQTLHIICGEEFNKLKEQVDGYSS
                     KFKKIVLGRPLLTHIEDYQEAVEAIKHQIPHMESNEAVVFMGHGTLHESHSAYPALEY
                     MLRDNGINAYVGTVEGYPEIEHVIRRLKEGNIKTVNLMPFMLVAGDHAINDMAGDEED
                     SWKTILEENGFNVRVHLKGLGENSYIQDKFVRHAVKCAENAKFYGIGAGPGDGSLLTI
                     KAVNTLKKLDILYTPESKKGGDSLALSIVSEYLPESVEIKSRHFPMSFDGNEKSLAWD
                     NVAQEIISDVNDGKNVGFVTLGDPMIYSTYVYIMKRILGEVEVETIPGISSFSNIASN
                     QNFPLVMDKEALVVIPCTMEDDKIEYALQNYNSIVLMKVYKNFKEIIKKLEKYDLIEH
                     AILVSNSSQESENVFTDLKEAHLEDKISYFSTILVNKDNKIK"
     gene            26529..27434
                     /gene="hemC"
                     /locus_tag="PC494_002105"
     CDS             26529..27434
                     /gene="hemC"
                     /locus_tag="PC494_002105"
                     /EC_number="2.5.1.61"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylbilane synthase"
                     /protein_id="HDF3912605.1"
                     /translation="MNIVVGTRGSNLALIQTEWVINELKKKYPEISFEIKIIKTKGDL
                     IQNVSLDKIGDKGLFVKEIEQQLLDGKIDIAVHSMKDMPSYLADGLKFAHTPKREDPR
                     DVLILREGYKNLDDLPHGAVIGTGSKRRKFQLLKQRPDLNIVQVRGNVETRIRKIKDE
                     NMHGIVLAASGIIRANLQDKISSYLPVDVVIPAPAQGALAIEIRSNDSTIEGIVNSLK
                     DENTEIQILAERGFLDGVNGSCHIPIAAYCEIIQDKIHLTGLYGDSEGKKVVIKSIDG
                     DISSPRELGLKLAKLVLKEYENYEG"
     gene            27424..28923
                     /gene="cobA"
                     /locus_tag="PC494_002106"
     CDS             27424..28923
                     /gene="cobA"
                     /locus_tag="PC494_002106"
                     /EC_number="2.1.1.107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uroporphyrinogen-III C-methyltransferase"
                     /protein_id="HDF3912606.1"
                     /translation="MKGKVYLVGAGPGDYKLMTLKGLECIRKSDVIVYDRLANSSYLR
                     EAKPDCELIYVGKASSNHILPQEDINRIIAEKAKEGKIVTRLKGGDPYVFGRGGEEAE
                     TLVDEGIEFEVVPGITSAIGGLCYAGIPITHRDHASSFHVITGHLKGDDSGELNWNAL
                     ANNKGTLVFLMGISNLEKISENLMKEGKDKDTPVALISWATRYNQRVVTSTLENVYET
                     AIKEEVKPPTLIVVGSVVGLREKLNFFESKPLFGKSIAVTRSRNQNSVLVEKIMDLGG
                     NPIEIPTIKVEKIQNNINLENEIKNINKYNYLILTSKNAVEIFFEKIYEMNFDLRILS
                     NLKVCAIGSATSNELKKRGIIADIVPKKFVAESLYEELAPILNDDDNILIPRAENARD
                     YLVDKLKAICEVTEVHIYRTVIDEEKKGEILDILNSNDIDYITFTSSSTVNNLVEIIG
                     KENIKILEKIKTLSIGPITTETINSLGIKLYKESATSTIDSLVDLIIKN"
     gene            28940..29905
                     /gene="hemB"
                     /locus_tag="PC494_002107"
     CDS             28940..29905
                     /gene="hemB"
                     /locus_tag="PC494_002107"
                     /EC_number="4.2.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="porphobilinogen synthase"
                     /protein_id="HDF3912607.1"
                     /translation="MLRRPRRLRASKAIRNLVRETKVNVEDLIYPLFVVEGENIKEEI
                     KSLPDVYHLSIDMLEDEIKEISELGIEHIMLFGVPDEKDECASQAFNDNGIVQKAIRK
                     VKEINSDINVITDVCMCQYTSHGHCGILTDTGYVDNDKSLEYLAKISVSHAKAGADMV
                     APSDMMDGRIQAIREALDENGLENVGIMAYSVKYASNYYGPFREAAHSAPSFGDRKTY
                     QMDPANSNEAIIETELDILEGADILMVKPALSYLDIIRRVKDNFDLPLAAYNVSGEYS
                     MLKFAVKEGLLNEDVILESITSIKRAGADIIITYFAKDIAKLLKK"
     gene            30058..30636
                     /locus_tag="PC494_002108"
     CDS             30058..30636
                     /locus_tag="PC494_002108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional precorrin-2
                     dehydrogenase/sirohydrochlorin ferrochelatase"
                     /protein_id="HDF3912608.1"
                     /translation="MLYPINLKLDELDVVIIGGGEVAYRKCKNFLEFNKNVTIVSKQI
                     LNKFYDLKGNIKIIKDDYKEIYIKDASVIIAATNNRELNMEIGLYCRAKNKLVNVVDN
                     IEISNFTVPSYIKRGDLLISVSTGGKSPSLSSKIKKEIEERYTEDYEEYLNVLGDIRK
                     KVIKKYEDKSKRKDVLNMLVTLDLEELKKFDI"
BASE COUNT        12420 a         3058 c         5672 g         9524 t
ORIGIN      
        1 tattattata aaatatttat attaaattgt ggaattaaaa tatactagga tataaaattc
       61 ttaaataaaa agaaaaggtt gtttttataa aaaatatttt ttataccact ttaaaaaaca
      121 caataataac actgagggag gtggggatat gagagaacgc attattcttg aaacattaaa
      181 aaatagtagt ggttatctaa acatagatta ttttgcagat aagttggggg tatctactcg
      241 aactatcaga aatgaaataa aaaagataga aactataaaa gaatgtaatg gttttaaatt
      301 agaatataag tctaaattag gatatattct aaatattaaa gaccaagata aattcgagca
      361 ttatctaaga aacttaccct cagatttagt tgaaaatcca gaacaacggt tggagtctat
      421 aatagtagag cttttagtaa atgaaggtta taaaactata gaacagttaa gtaaaaaatt
      481 tctagtaagt tcatcccaaa taaaaaatga tttaaaaaag atagatgaaa agataaagga
      541 tacagaatta aaactagagc gaaaggctca ttatggaatt aaaatagaag gttctataaa
      601 agaaattcaa agtatattgg tggatagtta ttttagaggg aatagaaata taacagagta
      661 caggaataag tttatagata atttaaaatt agctaatatt agaagtacaa taaaaaatgt
      721 acttaatgaa catgatttag aagcaaattt aacagaactt gaggaaatat tagcacaaat
      781 tattatattg tatataagag ttagtatgag agtagtggga aatgctagcg atttaaaatt
      841 atatacagaa gatttaatta tagataaatt attagataaa atttttagag ataaaaaata
      901 taaccttaat tatgatgaaa agtattattt aaaggagctt ataaaactaa agactaaaga
      961 taagaaagcc actataaaga atattgataa gaataaactt caagatatta tgttcgaatt
     1021 ttttagagag atagataaaa aatataactc taatttttta gaagataaag agttttttaa
     1081 cttattttac ttacatattg catgtttaat agaacgtata aagaagaacc acaagataat
     1141 aaatcctttt tcagttaaaa taagtcaaca gtatccaact gtttttaatt tatctattca
     1201 attttcaaaa atcatagaaa atgagtatca tataaaaata agtcaagatg aaatagggtt
     1261 tatagctact cacattgctg ttccttttga aaagagagaa gaagctaatt ttaataaaaa
     1321 atataaaata gcaataatat gctcttctgg tggaggtagt gcatttttga taaatttaag
     1381 acttaaagaa atttttccaa atgctgagat aagaaatttt tcattactag aagaaaaagc
     1441 tgtaatagaa tttgcaccag atttgatttt ttcaataaca aatcttttat ttgaaataaa
     1501 tgctccagtt atacttataa atgaaatttt agacgaattg gattatttag atattaaaga
     1561 aagtgttaga tttgcagacc atataggaaa tatatcaagc ccaaaacaat atatattagg
     1621 tctatttgat aagaatcact ttaggtgtat aaaagataaa gctaagtata aggatatcct
     1681 tgatagtatg tcaaaatgta tagttgacga gggagcttgt tctccaacct atcccaaaga
     1741 tgtatgggaa agagaaagtt atttgagtac tatttataca aatggggtgg ctatacctca
     1801 tccaatcgag atgacaggaa acaaaaatat aatatcagta gctttgatac aaactgatat
     1861 tatttatgaa aatagggtgc ctaaaattat tttcatgatt tcattaataa agggaaattt
     1921 agaacttcat aagcaaatat ctaaatattt aagtaagatt atggcaaata aggatatggt
     1981 agacatgcta aataagtcac aatcttatga agagtttatg tataagttaa aaatctatct
     2041 gggaggttag acatgaatat agagtttttt aagaggttgt cagaagcaga tggtatagca
     2101 tctaatgaag aagaggttag acatgtttta ttggaagaac taaaagctta tagtgataaa
     2161 attatctgtg atgggctagg gagtatcatc ttttctaaaa taaaagatga gagtgcacca
     2221 aacgtaatga tttgtgctca tatggatgaa gttggattta tggtgagaag tatagacaaa
     2281 cttggtatga ttcacttaat aacaatagga ggagtaaaac ctcttgcaca gtttgtacaa
     2341 aaagttagaa ttacaacaaa agaagggaag aaaatccccg ctgtcataaa tgctacatat
     2401 aataatggta aggctgaaaa tatatatgca gatattggag catatacaga agaagatgta
     2461 tataacctag ggattaatgt tggggatatg gtaacatata caacaagctt tgaggaattt
     2521 actttaccag accgattagt gggaaaggct tttgatgata ggataggatg ttttgtgatg
     2581 ggagaagttt taaaagaact taggaaagaa aatctaaatt gtaatattca ctttgcggct
     2641 acaagtagtg aagaggttgg aataagggga gcaaagacat caacacagtt aataaatcca
     2701 gatatagtat ttgtaataga tgtagcatgt gctaaaaatg agtttgtgag agactataca
     2761 aataagaaac aaattgataa aggtgtaatg ctaatgcata gagataggac tctagtccct
     2821 agtagaaaaa tgatagatta tgtaatggaa attgctgata aaaataatat accacttcaa
     2881 catgatatgt ttgaatcagg tgggactgat ggaggagaag cacatctcgt aaatgaaggg
     2941 aaaccttgtg tagtaacttg tgtaccagtt agatatggtc attgtgcatt ttcaatagta
     3001 agtaataaag atttggagaa cattataaga ttgtatacac agttaatttt aaattttgat
     3061 gaagaacaat ataaacatat aagaaatttt atctaaagga gaataagaaa atgtcaacag
     3121 aagtacaaat aatggaactt atatcaactg caggagagag taaatcgaaa gcttttgagg
     3181 ctttaaaaaa agtgaagtca aaagatttta aaggagcaaa attgttaata gaggaggctc
     3241 gtaaaataga tattgaagct cacaggatac aaacagaatt aataactcaa gatttaaatg
     3301 aagatgttga aagtccagca atgagtcttt taatggtaca tgctcaagac cactatatga
     3361 cttctcagct agcaaaagac ttgatagagg ctttgatata ttgtcttgat aagtaattgt
     3421 aatatagaaa tagattattt atgtaaaaat tcttttaaaa gtttagatgc ttttaagaga
     3481 taataaaaat acaaacttta ggaggaatta ttatgaaaat attattatgt tgtgcaggtg
     3541 gattttctac taatatgtta atgcaaaata tgaaaaaggt ggtaaaagag agtgctaaac
     3601 tcaatgaaaa agattttgag tttacagcta taccagcaga ttcaatagaa agtgaagttg
     3661 atgattggga tatagtactt ataggtcctc aaatagctca caaaatagac ttcttaaaag
     3721 gaatattaga gccaaaaaat aagccttttg cagtaataga taaagatgta tatggaaaaa
     3781 tggatggagc tacagttatg aagttggcat taataactta taagaaacat caattagctc
     3841 aaggataata aaaataatga gggaaaaggg agattagata tgttttcaaa atttgaagca
     3901 tttatgaata gagtatttat gcctttagct cataaggttg acaatcaacg tcaccttggt
     3961 tctataaagg ctggtatggt tgctatgaca ccattcacaa tattaggaag tatatttgca
     4021 atacttccag cacttccaaa tatgcttgga gaaaataatc caataagcaa attcatactt
     4081 agcaattcag caatattgga tttaccagta agtctttcca taggtttaat aggattatat
     4141 gcttgtatgt gtattgcttt taatctgggg aactactata aattatatat accaggttgt
     4201 gttgcactat caactttttc ttttttattc ctagtagcct catttacacc agatggagct
     4261 ttagaaatag gaaatttagg agctaaaggg ctatttacag gtatgatagc agggcttggt
     4321 tctgtggagt tatataattt ttgtaataag aagaatatca caataaaaat gccagaaaat
     4381 gtacctgatt ttgtatctag gtcttttgaa ttaataccta ctactataat agtttgtgga
     4441 acttttatag ttgctcgttt tatttcatta aaagtatttg gagaattacc tccacagata
     4501 cttactcaat ttttatctcc attagtagga agtatggata acccatggtc agttcttgca
     4561 cttaactttg ctatatgtac tatattcttt tttggaatac attcatcagt atttagtcct
     4621 ataactagac ctataatgat tacatttata gctgaaaaca tagcagctat gcaggctgga
     4681 gaaacaatac ctcatttctt tacagcagga gcttcaagtg cattctttgg atttacagga
     4741 tgtggaatta gtataggttg tgtaattgca tgtatgttat caaaaaatgc ttcctataag
     4801 aagattggac gtgtatcatt attccctgca ttatttggga taaatgaacc aatattattt
     4861 ggagcaccga taatattaaa tccaataatg tttataccac atgtatttgg tggagctata
     4921 ataggtacac taccaatgtt ttttatgcac tggggatggt tagcaaagcc agtatttgac
     4981 cctccatatg taggggtatt cttagaagga tttttaacta atggagattg gcattctata
     5041 ttagcaaatg cattgcaatt agtattagca gttttattat attggccatt ctttaaaata
     5101 atggaacgtc aacaaaataa taaaaaacaa aaagaagaaa ctaagaatat attctctaaa
     5161 gaagaagaag acttattgga tgatttagga ttggatttct aatattttgt tatgaataat
     5221 acaatggaga gattagtatc cttaatctat aaaagaggtg ttgacgctct tttgattaaa
     5281 gcaaaaaata ctaaaagata tataggagct ttatcaggta gtggtgtata tgtgcttgtt
     5341 actaaggata aaaattatca aattctagat ggcagatata ttgatgaagc agataaaaaa
     5401 acgactggtt tcataaaaag gattgtatct caaggttctt atataccaac tataattgag
     5461 ttattaaaag aattaaatat aaaaaagtta gcaatagaaa accaagctat gagtatacaa
     5521 gagtatcttt cactaaaaaa tgaaggtttt gaaatcaatt taataacaaa tgaattatgg
     5581 aagctaaggg ctataaaatc taaagaagaa attaaactta ttaaaaaggc ttgtgagatt
     5641 acagatgaag tatttgatga ggttatttct gaaattaaaa aagatatgac tgagctagaa
     5701 gtatcagctc taattcagta tcatgcatta aaaaaaggtg caagtggaat gtcttttgaa
     5761 acaatagtgg tatcaggaga aagaggtgca atgccacatg gaagacctac aaacaaaaaa
     5821 ttgaaagtga atgaagctat aacaatagat tttggtgttg tttatcaagg gtatcaatca
     5881 gacatgactc gtacaatatc tataggcaaa cctcctaaaa ttattaaaga gatatatgat
     5941 gtagtattgg aagcacaatt atctgcaata gagtcaataa aggaaggaac tagggcaagt
     6001 gatgttgaca aagtggctag aaaaattata gataaacatg gatttggcga atattttaat
     6061 catggactgg gtcatggtat aggtcttgga gatggtgaag ttcccacttt aaatccaaat
     6121 agtgaagata tattagtgga aggaatggta atgtcttgtg agccaggtat ttatattcca
     6181 aatgtagggg gagttagaat agaagatgat attgttataa tagatggaaa aggtgttcca
     6241 ctcaataaga catccaaaga gtttataata ttaggagagt aaaattatga aatataattt
     6301 taataaagta ttaaatcgta aagaaggaaa ttgtagaaaa tggagcaacc atgtgattaa
     6361 agaaaaattt ggcttaaatg aagatgcaat tcctatggat ttagctgata tcgattttga
     6421 gtgtgctcct gctataaaag aatctatctt aaaaagagca tcagtaggag attatagtta
     6481 tacttttata ggagatgact tctatgatgc tattataaat tggaataaaa gaagatttga
     6541 tgtatatata gaaaaggatt ggataaaatt aacttttggt actgtttcaa cccttcatta
     6601 tatagtccaa gcatatacta aagaaggaga gggtgtattg ataaatacac ctgcttatga
     6661 cccttttgca gaggctgtag taaataataa tagaaagttg tgttgtagct cattaaaatt
     6721 agataacaat agatattatt tagatttaga ggatatggaa aatcaaatga aatacgagaa
     6781 tataagattg cttatattct gtagtccaca aaatccatca ggtcgtatat ggacaaaaga
     6841 agaactatat caagtgtcag agttatgttt aaagtataat gtaattttgg taagtgatga
     6901 aattcataga gatataatat ttaaagatta tagatttgta tctttgtgga atgctcatcc
     6961 agaaatttat aaaaatagta taatctgtgt atctcctaat aaaggcttca acttaggtgg
     7021 attaaaaaca tcatatgtat taataagaga tgtaaaaatt agggagactt tattagaaag
     7081 gctaaaaagt aattcaataa cttctccaaa tgtatttgca ataccagcaa tagttgcagc
     7141 atataatgaa agcgaagaat ggctagatgc tatgactagt tatgtagagg agaattttga
     7201 aatagtttat gatttctttg aaactaatat accaaaagct aaagtgatga agtcagactc
     7261 ttctttttta gcctggatag atgtaagaga agtatttaga aatgaagaag aatctaaaga
     7321 attttttaga catgcaaact taactatggt agttggaagt tattttgtga aagatggaga
     7381 tggatttatt cgtattaatg tggggtgtcc tagagaaaca ttaaatgagg ctctaaatag
     7441 aatcaaaaaa acgtatataa gtatgtattg ttaaatcata aaaaaagtat ctatggttta
     7501 tataaaaaca cattatttag ttatcaaata ttactggaat tttgtattcc agtaatattt
     7561 tttgattaag gaatattatt gaggaatatt aaataatatt atttcatacc cttatattaa
     7621 cttatataaa aatattttat tattttggga acgggttagc taacctttat ctagtgtata
     7681 tttatattgt aagaagcagt aaaaactttt cctttactaa gtttattaat aaacttctta
     7741 tctttataaa ttttgttaga atttatacta tcagcaagac cataccaagg ttctatacat
     7801 aaaaaaggag cagtagaatt agtttcacta taataaggag tccaaatacc aactagaggg
     7861 aaatcttcca tagatatagt tacatattta ctaccatcat tattacatat agacacttca
     7921 tctatgttgg tgtatatcaa agcatcattc ttgaatactt ctggatttaa ctgtaagttt
     7981 tttaattttc caataggtat tatatcatct gtaaaagaac catttaaatt gattttttct
     8041 acatcatttt tacttttaaa ctcaaggtag tgtttagaaa aatcattttg ttcgtaaaaa
     8101 ggaaggttga atgcaggatg tccacctata gaaaagaata tatctttaga atcagtattt
     8161 tttacaatcc attctacctc aatactatta tcatttaatg tatagtttat gattagctca
     8221 aaagaatatg gatacttctt taaagtagat tcattatctg ttaatttata agttacaaat
     8281 gtatctcctt tatctacaat ctcaaagtcc atatctctag caaacccatg ttgagtcatg
     8341 ctatataaat tttcttctat tattgtttca ttatcaaaaa gtttacctac tatagggaac
     8401 aatataggtg attgtctacc ccaatatttt ttattaccat cccaaagaat gtttttgtcg
     8461 tattttttag aaaatatttt agttagttca gcaccaaaac tgcttgattc gataattaaa
     8521 ttttcatttt gtaatatatt catttaaaat ctcctttatt atattttatg agtatattat
     8581 actataaagt ataaagatta ttaaatttta tttgatatta tatttgaaag gtagatttta
     8641 gtatattttg aaaattttgt tttgaaaatt tgggattatt taagaaattt tgtattataa
     8701 atagaaggaa atagataaat tgtatagaat aaaatatatt aagataagtt aataatgtta
     8761 aatgggaagt gagtttatgg aaaaaccaaa tacaaaagtt gttaactttc aagagtataa
     8821 agacagaaaa aaccaaagag aagtaaatag agacgaactt ttaaagctta taaaaaaaat
     8881 tgtgacttca aaatagggag ttgttaaact ccctatttta atgggtttca taataattaa
     8941 gacattctaa gtccatctat ataatctttg aattgtgaga aatctgattc actacttaat
     9001 tctatggttt ctgaaccttc cgtataaaaa ttcttaagat agatagtata attattatca
     9061 acacaatcat gataaataca tctatatcca tcttcataca aactttttaa cttagaaaaa
     9121 tcatccacaa tatcatctcc ttaaagttct tttaaatata tttttacaaa aagcatctaa
     9181 ttgtatgcaa attgacaatg taaaataaag gaaatgaaca taaaatgtag aataattttt
     9241 atatgtatgt aaaaataaaa agaaaaagtt gaaattttta gaaaataaga gtatttttta
     9301 tctaaaaaga gagtttaaaa aataaaaaaa tgttgggagg ataaaaaatg agtttattag
     9361 aaagtatatc aaaaaacata tattccctag ataactcttc tattgaaaaa acaaagcaga
     9421 gattggatag gcttatacat ccaactggaa gcttaggaaa gatagaagat atttgcatgc
     9481 aattagcagg aatatttggc aatgaaaatt ttgacacaag taaaaaggtt ataattgctt
     9541 ttgcgggaga ccatggtgta tatgaagaag gcgtagcacc tgaccctcaa aatataacaa
     9601 aattacagtt tccaaatttt tcgaaaggtc tatgcggagt tggagtaata agtaaatttg
     9661 taggggcaga tgttgtagct gtagatgtag gaataaactg tgatgaaaaa ctggatgggg
     9721 tattagacta caagataaga aaagggacat caaatatggc aaaaggtcca gctatgagta
     9781 aacaagaagc aattagatgt ttagagatag gtattgaaat agcagagcag tgtatagaaa
     9841 aagattataa ggttattggt attggggaga tgggtatagc aaatactact ccaagtacag
     9901 caataatatc tgtaatttca gggtgtgacc cgttagaagt tactggtata ggtgcaggtc
     9961 ttaagaaaga aagactaaag cataaggctg aagtaattag aaaggctatt gaaattaata
    10021 atccaaatcc aactgatgga gtagatattt tatctaaagt aggagggttt gaaataggct
    10081 caatggcagg tgttatatta ggttgtagtg ctaataggat tccagtagta attgatgggt
    10141 ttatttctta tgcagcagca ttaattgcat ataagataaa tccaaaaact agagaatata
    10201 tgatagcatc tcatttatca gcagaatcag gaactaaaag agcattagac atattaaaat
    10261 tagaccctct attaaatatg gatatgagat taggtgaggg aagtggagct gctttagcat
    10321 ttgatataat agaagcttca aactatactt ataaaaatat ggcaactttt gatgaaattg
    10381 acatgggaag ataaatataa aaatttaata tgtaggagtg ttttgatgag taaaattatt
    10441 ctagtaacag gaggagctag gtcagggaag agtaactttg cagaaaaact atgttttgac
    10501 agaaataata atacagctta tatagcaacc tctattccat ttgatgatga aatgaaagat
    10561 agagtaaaaa aacatcaaga gaatagacct agaaactgga atacttatga aatatatgaa
    10621 gatatatatt ccataattaa ggagatatat aaagaacatg aaactgttat actagattgt
    10681 gtaacattat tagtaaataa tctaatgttt gaacacaatc taaatataga agaatctagt
    10741 caagaagaaa taaacaaatt agaacaatac ataaaagaac aagttgtcaa acttattgaa
    10801 gaaatagaaa aaacaaatct atactttgta tttgtaacga atgagttagg tatgggaatt
    10861 gttcctggga ataaacttag tagaatttat gctgatattg taggtcgtat aaatcaatat
    10921 atagcttcga aaagtaatga agtttatttt gtagttagtg gcatagctat gaagataaag
    10981 gagtagtatg caattatgaa aagatttatt ttaatactac agtttttgac aaggatacct
    11041 ataaaattaa atgtaggatt tgatgatgaa ttttataagt caatagtata ttttccactt
    11101 gtaggttttg tcataggtat attatcctat ttaataggat ggatttctat gcttttattt
    11161 gaaccattta tagcttctat aataataact ctagctggtg tcttaattac tggaggactt
    11221 catatagatg gattaggaga tacatttgat gcaatatata gttataggga taaagaaaag
    11281 atgcttgaaa taatgaaaga ttcaagatta ggtacaaatt cacttctagc aattatgttt
    11341 gtacttttat taaaggttgg attcgtttac gatataataa gtaataattc attgtgggtt
    11401 ataattttta tgccaatgat tgcaaggtta ggagtaatgt tattgacata taaaactgtg
    11461 acaccaagag aaaaaggaat gggaaattta tttataggaa aattaactac aagtatgtta
    11521 ataactgcta taatatacac attattgata gttgctctta ttactaaatt tatattttta
    11581 ttacctaata tagtgttgat taaagtatta ggttcgatta tagtggtttt tgtatttata
    11641 atattattca aaaaacatat ttataaaaaa attgacggag taacaggaga tatattaggc
    11701 tgtggaatag aactttcaga gcttgtatat ttaatttaca tatatttgtt aatttttatg
    11761 tttttttaaa gtaaaaagtg gtgataatat gataagatta atattaataa gacatgcact
    11821 gacaaatgat aataaaaaag gaagattatc aggccatata aatagttgta ttagtgaaga
    11881 gggcaaacta caaataaata aaattaccag atatctgagt aatgaaaaca tagataaggt
    11941 ttatacaaca ccatctacac gtactaaaga tacagtagaa aaaatatcaa aattgaaatt
    12001 attagaaata gaagaaaaag aagctttaag agaaattagt tttggagact ttgaaggaag
    12061 aacttttgaa gaaattaaaa tcaaatatcc aaatgagttt gaaaaaatga taaaagaagg
    12121 taacaactat agatatccaa atggagaaag tttgatagac tcttataaaa gagtggcaaa
    12181 agaaattgat aatataattt tagaaaataa tagtaattta gatacaaaga caatacttat
    12241 atgttctcat gcaggaacaa taagaaatat aataacacat ttgatttctg gtagttataa
    12301 gtatcactgg aactttaaaa ttgataatgc atctattaca gttttagaaa ttgatggtgg
    12361 atttgctgta atagataaaa tgaattttac agacttcata taatttaatc aaaaccaaac
    12421 attacaatct gtgtttgtaa tatatctgta aaattagcaa tgaaaataga atattagatt
    12481 aaaattaggt tcttaattag atgttaaaag ggaaaaaggt tagatgcctt tgcagccccc
    12541 gctactgtga aaccaacgaa actataaata ccactgtcag tttgatggga aggttataga
    12601 agtaggatga agttaagcca ggatacctgc ctaatttaat ttaaaacaag aggtcttcgg
    12661 ggtgaaagat ttttaattaa tatatataaa agtcctatct ttagaagtat taggactttt
    12721 tttaatttgt tttttagtaa attttaacaa ggagggatgg aaagtgggga aaaaaataat
    12781 gctacaagga acagcttcaa atgtaggtaa aagtgtctta gtagcaggtt tgtgtagaat
    12841 atttaagcaa gatggttata ctgttgctcc ttttaagtca caaaatatgg ctttaaattc
    12901 ttttataact aaagaaggat tagaaatggg aagagcacaa gtatttcaag cagaggctgc
    12961 gaaaatagag ccaatagctg atatgaatcc agttttatta aaaccttctg gaaataataa
    13021 aagtcaagtt attgtaagag gtaaagttgt aggagaaatg ccttcttcta agtatcatga
    13081 ttataaattg gagttagtag atgtgttgaa ggaaacattt aatagcttaa attcaaggta
    13141 tgatattgta gttatggaag gggcaggaag taatgcagag ataaacttaa aagatagaga
    13201 tatctctaat atgggtatgg cagaaatagc tgatgcacct gtaataatag tcggagatat
    13261 tgatagagga ggcgtatttg cctcattagc aggaacaatg cttttattaa atgaagatga
    13321 gaaaagaaga gtaaaaggtg taataatcaa taaattcaga ggaaaaaaag agcttttaca
    13381 agatggtgta aagatgctag aagacatcat aaaagtacct gttataggag tagtacctta
    13441 tacagatata aaaatagaag atgaagacag tgtaactacg agatttaaga aaaaaatgaa
    13501 taaaagtgat atacacatag aaataattag aaccccacat atgtcaaatt ttacagattt
    13561 taatatattt gagacacaag aagatgtaag tataagatat gtagactatg gagaatcttt
    13621 aggaaatcca gatatattaa taatacctgg aactaaaagt actatagacg atttaacata
    13681 tataagaaaa agtggtcttg aatcgcaaat caaaaattta catagtcaag gtaaattgat
    13741 atttgggata tgtggtggat accaaatgtt aggtaaaaaa ttaaaagacc cttatcatgt
    13801 tgaaagtgaa attgaagaag ttgatggaat aggtctttta gatacagaaa caacgtttga
    13861 gaaagaaaag actacaacac aagtagaagc tactattgtt gaatgtatca gtgaatacat
    13921 gaataacctt aagggaaaaa aagtaaaagg ttatgaaatt catatgggaa ttacaaagcg
    13981 aggtaatgat gtaagaagtt tagatttaat aactaaaaaa cttgataaag aagtgaatta
    14041 tactgaggga agtgtaaata aagaggggaa tgtaattggg acttatcttc atggaatatt
    14101 tgatgaaata agctttacaa gagcaatttt aaacaatata agaaagaaaa aaggtttagg
    14161 agaattagaa agcaaagtaa actcttttaa tgaatttaag gataaagagt atgataagtt
    14221 ggctgatttt ttaagagaac atttagatat agagaaaata tatgagatta tgaaataatg
    14281 atgaccttta tttataattt aggtaggagg tgtattatga aaaaaatttt aattgcgggt
    14341 actaatagtg gagtaggtaa aacaacaata tcattaggaa taatgcaagc tttggttaag
    14401 agaaatatga aagtacagcc atataaagta gggccagact atatagaccc ttcatatcac
    14461 acttttataa ctggaagaca ttctagaaat ttagattctt atatgttaga tgatgaaaaa
    14521 ataaagtata tagtaaataa gtcctcaaaa gatgcagata tttcagtaat agaaggtgtt
    14581 atgggcttat atgatggttt tggaatagat ttagataatt gtacaagttc acatacttca
    14641 aaggtattaa agtcacctgt tatattagtt ataaatggta aatctatggc agcatctagt
    14701 gctgctatgg tacttggata taaggaacta gataaagatg taaatataaa gggtgttata
    14761 gtaaataatg taaagactaa tagccattat caaataatta agagttctat agaaaaatat
    14821 tgtaatgttg aagtattggg gtattttcct ccaaataaca aattctcttt ggaatctcga
    14881 catctaggat tagttcctag tgtagaaatg aaatcactaa gggaaaaatt ttatacctta
    14941 gcagatgaaa ttgaacacta tatagatatt gacagaataa ttgaaatatc agaaagtgat
    15001 gaatttgaga gtgattttga ttttcaaact ttgatagaaa ataataaaat aaaagaacat
    15061 gttaataata aatcaatagc tatagcatat gataaagcat tcaattttta ttatagagaa
    15121 aatatagagc ttttagagga acttggttta gaaataaact attttagccc tcttgaagat
    15181 gcatcagtgc caaatgcaga ttatatatat attggaggag gttttccaga aatatttgga
    15241 aaagaattag aagcaaatga gtcaatgaga acttccatat tagaagcaca taacaataat
    15301 atacctattt atgcagaatg tggaggactg atgtacctag gtgagaaact attgaatcaa
    15361 gaagaacaag aatttaatat ggttggaata tttagtggaa ttagtaagat gacatcttct
    15421 ttaaagagat ttgggtactg tattggtgta gccaaggaaa atactctttt atctaaaaaa
    15481 ggggaatcta ttaaagggca tgagtttcat cattcaatat ttgaaagtga tgaaaaatgt
    15541 gtatattcaa tgagaaaaga aagagatgga aatatagtag aagagtggga tggtggttat
    15601 agtaaaggaa acactttggc tacatatctt catactcatt tttataataa cttaaattgt
    15661 atagaaaatt ttttgaaaaa aggaaatgaa taaatgagta ttttatctat ttatatagga
    15721 tatgtgacag acttaattgt aggagaccca tattcttttc ctcatccagt gagatttatt
    15781 ggtaaactta taaattttac tcaatgtata ataagaaagg tctctaaaaa tgataggcag
    15841 ttaaaatttg ggggatttat attatggctt ataaccgttg gaataacata tttaacaact
    15901 tatgctatag tgaagttatt tagttttaat atattattga gtattgtagt gaatagtttt
    15961 ataatttata caacactagc cacaaaatgt ttaaaagacg aagcattaaa aatttataat
    16021 gtattaaaaa ctgaagatat agaaaaatct aggattcagc tatcttatat agtaggtagg
    16081 gatactacta atttaagtga acctgaaata ataagagcaa ctgtagaaac tgttgcagaa
    16141 aatactgtag atggtataat tgcgcctatg ttttatgcat ttattggagg agcaccactt
    16201 gctatggcct ataaagctat caatacattg gactcaacag ttggatataa aaataaaaag
    16261 tataaagata ttggttttgc atctgctaag attgatgata tagccaatta tataccagct
    16321 agaatatctg tcattcttat gacaattgga agtttctttt taaattataa ctataggaac
    16381 tgttttaaaa tctctattag agatagaaag aatcataaaa gtccaaattg tgctttttca
    16441 gaaggtgcag tatctggtgc tctaggaata caactaggag gtaccaacgt ttattttggg
    16501 gaaaaagtat ataagccaac aataggggat aagcttaggg agatagataa agaagatata
    16561 attaaaacta ataaaattat gtatgcatct tcatttgtat ctatgttggt atttacacta
    16621 atatatgtgt tatgtaggat gattttaatt aacttaatta tataaattat tgtttgttaa
    16681 cttaaggggg acatagatga aggatttagg gcatggtgcc aatgtagatg aaatggcaag
    16741 attatatggg aaaaacccaa aagaaataat tgattttagt tcaaacataa atccaaatgt
    16801 attaccaaat ttagagagat acattttaaa aggattagaa gagtgtagga attatccaga
    16861 tataaattat acaaacttga gagaaaatat atcaaaatat atagatataa atccagactt
    16921 tataatacct ggcaatggtg caacagaagt gatttatttg cttatgaaga gtattaaaaa
    16981 aaaattggct ataataaatc cgactttttc agagtataga agaagtgctg agttaaataa
    17041 tttagatatt atagatttag aattagattt agaaaataac tttaaactta atatagatat
    17101 aataaaagaa aatataaaaa gatttgatag tttatttata tgtaatccta ataatccgag
    17161 tggtaatgtc caagatttaa aggaacttgt tcatttacta gataaacata ataaggtact
    17221 aataattgat gaaactttca tggaatttgt tgaagatgaa agtaaatata gtttggttaa
    17281 atatatagaa tcaaataaaa atatatttat aattaaagct gtgactaagt tttttggtat
    17341 gcctggttta aggctaggat atggtcttac aagcaacact gaaattatga acaaaattta
    17401 tgaacacaaa gagccatgga ctatcaattc ttttgcagat atactatcca attttatttt
    17461 tgaagataaa gagtatatta aaaatagtaa agaatattac atagaagaaa gaaaatatat
    17521 gttacaagag ttgagaaaca taagaaatat aaaggtctat gatacagatg ctaattttat
    17581 cttgataaga atatataaaa aaacaactaa agaattgaaa aaagatttgt ttaagcaagg
    17641 aaacatatta gttagagatg cgtctaattt tataggatta gatgatagtt ttataagagt
    17701 ggctataaaa tctcatgaag ataacaaaat tcttatagaa aatatgaaaa atttattggg
    17761 tgattaaaat gaaatcttat ggaatatgcc cagcatcttg tggagaattt gtacaaggta
    17821 taattgatga tgaagaatat ttatgttcat atgcaataga tatgtattct aaagtgtata
    17881 ttgaagaaaa attagtagat ataaatttag ggagatataa gtcaaggtta gcaattgaaa
    17941 aggtatttga aaaatttaat ttacctaaaa aatatactaa aaatatttct ttaaatataa
    18001 atagtaaaat acctgttgga aaaggaatgg caagttcaac tgctgatata ggagctacta
    18061 taaaggcaac attatcattg atagataaag atttaagtag cgaggagatt tctaaattag
    18121 cagcagaaat agaaccaaca gattctatat ttatagataa aaatagtata tttaatcctc
    18181 taaatggaac tgttataaaa tacctaggaa atctgaccaa tgcgaaagtt gtaatacttg
    18241 aaccaaacaa agtactagat actatgaaga ttagattgag gcaagattat aataaattaa
    18301 aagtagagaa taaagaagta ataaaaaaat catttgctct tttagaagaa ggattgaaaa
    18361 aaaataattt atctctagtt ggagaggctt gtactttgag tagcttagca aatgagaata
    18421 tagaaaaaaa agagtgttta aatgaaataa taaaaatatc aaaaaaatat ggagcatatg
    18481 gagtaaatat tgctcacagt ggaactgtag taggtatttt aattgataag tctatgaatg
    18541 ataaaaagat gatagatgcc ttatgtgaat ctaacataaa ttctgtctat aataaaattt
    18601 atacacaaaa cataattaat ggaggaatta agggggaaat agaatggaat acataaagaa
    18661 tcctatgaaa atagaagaaa aaagttttga attgatacaa gaaataatag acgaaattag
    18721 accagattat aaatttaaga ataatatcga agaaaaaata ataaaaagag ctatacatac
    18781 tactgctgat tttgattact tagatatatt aaaaatatca gaagaagcag ttgatagtat
    18841 aatagatgca ttaaaaaata atgcaagtat ttatactgat acaaatatgg ctcttagtgg
    18901 tataaataaa agaaagttag aatcattagg atgtaagtat aaatgtttag tggcagatga
    18961 tgaaactgta aaattagcta aagaaaaagg aattactcgt tctatggcag cagtagaaat
    19021 tgcagctaaa gaagaaggaa gaaaaatatt cgttttaggt aatgctccaa cagctttata
    19081 taaagttatg gagatgaaat cagaaggtag attagattta gatgcagtta taggagttcc
    19141 tgtaggtttt gtaggagcac aagaatcaaa agatgaagtt gaaaaaacag atataccata
    19201 tataatttct aaaggtagaa aaggtggcag taatttagca gcagcaatag taaatgctat
    19261 attatatact atgtaggtac ctatatggaa gaatatgtat atatagatgg aaaaaaatat
    19321 agaagaggat atactacagg ttcatgtgca acaggtgcat ctaaggctgc tgtatatatg
    19381 ttgattacaa aaaatagaat caatactata aatatagata ctcctaaggg gataccatta
    19441 ctactaaaag ttgataatat aaatatttct gatacatttg tggaatgttc cataaaaaaa
    19501 gatggtggag atgatataga tgcaactcat accatggata tttatgcaag agctgaaatt
    19561 gtagctaaaa atgataagaa caaagggtat cttactctaa aggatataga tagtttaagc
    19621 accaatagtg agtgtaaaag tgagctctat aagtttatta gggtttatgg cggaactggt
    19681 attggtgtgg ttacgaaaaa agggcttagt gtggatgttg gtaagcctgc tataaatccg
    19741 actccactta aaatgataaa tcatgaaata agaaagctta taggagataa ttttgaatct
    19801 atacttggaa atgataaagt tttaaaaata acaatctttg ctccacaagg agaaactgta
    19861 gcaaaaaaaa catttaatcc aagattaggt atagttggag gaatatctat aataggtaca
    19921 actgggattg ttgaacctat gagtgatgag ggttggaaga agtctctatc tatagaactt
    19981 cagatgaaaa aagaacaagg cttagataaa ataatattgg ttccaggaaa tcatggagaa
    20041 cagtttataa gagaaaaatt aaacttagat attaagtatg tagttagggt aagtaatttt
    20101 ataggctata tgattaaaga agctcaaaga ataggatata agaaaatctt aatggcaggt
    20161 catataggta aatttataaa agtatctgct ggtattttta atactcatag taaggtagca
    20221 gatgctagaa gtgagatatt agtggcaaac ttagctttaa tgggagctag atacgaattt
    20281 ttaaataaaa taaatcaatg cgtaactact gaagaagctg tagagctaat aaataatagt
    20341 gaatatagag aagtatataa tatattaagt aataaatgta gggagagagt aaagcaatac
    20401 ttgaatgaag attcagatga tattgatgtg gaagtaatca tattttcaat ggataagtct
    20461 ttattaggta aatcggataa tacagatgat ttagtggagg tctttatatg ataaacataa
    20521 taggtctagg acctggcaac ttagactata taacaaaaaa aggtgaaaat ttaatttcca
    20581 cttctgatgt attaattggt ggtaaaagaa atttagagtc tataaaaaat tttgaaggag
    20641 aaaaaatagt tctggattct aatttaagag aaattataga gtacataaat aacaataaag
    20701 aaaagcaaat atcaataata gcatctgggg acccattaat atatgggata ggtagatatc
    20761 tatctaaaaa tattgataat aagatgttaa acatggtttc tgggattagt tcattacagt
    20821 acatattttc aaaaatatat gtagatatga atgatgtata tattacaagt agtcatggta
    20881 aagtaccaga ttttgattac atattatcac ataaaaaagt atgtatggtt acagattcaa
    20941 agataggacc aaaacaaata agtagagaaa taatagatag aaatctaaat aaaattattg
    21001 ttgtaggaga aaatctgtca tatgacaatg aaaaaataac aatagcaaaa ccagaagaga
    21061 taataagaat agacaatttt gatatgaatg ttgtggtgat tttagatgag gaatagtgaa
    21121 tttataacag gtaaagttcc aattactaag gaagaggtta gagcaatatc aataagtaag
    21181 ttaaatttag taaatgctaa aaacctcata gacatagggg ctggtacagg aagtgtaagt
    21241 gttgaagctg catataatta tcctaattta aaggttatat ctatagagaa aaatgatgat
    21301 gctatagagc ttatagagaa aaatataaaa aaattcaact taaaaaatat agaagtgata
    21361 aaaggatgtg ctccaattaa tctagggtta aatgttaaag ttgagtctat ttttcttggg
    21421 ggaacaggaa ataatctgga agaaataata gaatggtcta aaaaaaatct cgttacagga
    21481 ggaagacttg tagctaattt tataataata gatacattta atcaaacttt aaaactgctt
    21541 aaaaagcatg gatttaaaga aatagatgta tgtgttttga atgtttctaa actggagaaa
    21601 ctaggaaaag gtgaatattt taaaccacta aatcctatat atataatatc ttgtgaaaaa
    21661 ggggaaaatg atgatgaata aagtacattt tgtaggagca ggacctggag ataaagagct
    21721 gataacatta aaaggataca aattattaag taatgcagat gtagtgatat atgcaggttc
    21781 acttgttaat cctgaacttt tggaatactg taaagaagat tgccaaatac ataatagtgc
    21841 acatatggat ttacaagaga taatagatgt tatgagagaa ggtatagaaa ataataaatc
    21901 tgttgtaaga ctgcaaacag gtgatttttc tatatatggt tcaattagag aacaagtgga
    21961 agatttaaat aaattgaata tagattatga ctgtactcct ggagtaagtt cttttttagg
    22021 ggcagcatca tctttagggg ttgaatatac agttccagaa atttctcaaa gtgtaattat
    22081 aacaagaatg gaaggcagaa ctccggttcc agagaaagaa tcaatacaat catatgctaa
    22141 gcatcagaca tctatggtaa tatttttatc tgttcaagaa attgagaaag ttgtgtctaa
    22201 attactggaa ggtggatatc caaaagatac tcctatagca gttatataca aagcaacttg
    22261 ggcagatgaa aaaatagtta aaggaacttt aagtgatata gctgtaaaag ttaaagaaaa
    22321 caacataaat aagactgctt taataatggt tgggagattt ttaggagaag agtataataa
    22381 ttcaaagtta tatgataagg atttcaaaca tgaatataga gggtaatatt gctataatct
    22441 gtattacaga aaatggaaaa aaattagctc taaagataaa ttctctagta aataactgtg
    22501 ttatatatca agtaaaaaat aaaaaaagta atttagttgt tgaagaaaca tgtgtacata
    22561 cagttcaaaa gaagttaagt gattttgtag gagaaatatt tagtaaattt gattacatag
    22621 tatttataat ggctacaggt atagttgtac gaagtatagc accatacata ataagtaagt
    22681 ttagtgaccc tgcaattttg gtaatggatg aaaaaggcaa aaacgtaata agtttattga
    22741 gtggtcatat tggaggggca aacagcttga cacagtacat aagtagtctt attgatgcta
    22801 atccagtaat aacaacagct actgatataa atcaaaaagc ttccttagat atgatagcaa
    22861 aaaaactaaa tgcacatatt gataatttta gagaaagtgt aaaagaagta aattctatgc
    22921 tagtgaataa taaatgtgtt ggattatatg ttgatgaagg atatcaagtt gatactaggg
    22981 gatttaaact tatagaaagt aaggatgagt taagagatag tttttcaaac acatatatag
    23041 aaaaattagt tgtagtaagc aataaaataa attgtattga agatattgag aatttaaacc
    23101 tagataataa atttgaacat tgctatagta cccaaaaaat aataaaggta attccaagag
    23161 atatagtgat aggaattggc tgtagaagaa acacagatag tgaactgatg tataattcac
    23221 ttgaagagtt tcttaataaa caaaatatag atattagagc aataaacaca gttggaagta
    23281 tagaactgaa aaaagacgaa aaagcaataa ttgaattatc aaaaatattg aaggtgccat
    23341 ttaaaacatt ttcagtagat gaaatatcta aggttgataa tctttttgat aaatctgatt
    23401 ttgttaaaaa aaatgtgggt gtgtattcag tagcagaacc tgtagcatat cttttgagca
    23461 aaggtaattt gttagttgaa aaacataaat ataaaggaat aactttttca gtggggagaa
    23521 taaaaatatg atatacgttg taggaattgg accaggaagt aaagatacaa tgactttaga
    23581 agcaataaaa gcaatagaag attctgaggc tattgttgga tataagactt atataaaact
    23641 aatagaagaa tttatacaag gtaaagaaat aatccaaaat ggtatgaggc aagaagttga
    23701 tagatgtaaa caagcagtgg aggaagcaaa aaaaggaaaa aaagtagcag ttgtaagcag
    23761 tggtgatgct ggaatatatg ggatggcagg tcttatttta gaattaatat ctaaagaaga
    23821 tgaagatata aaagtaaagg taattccagg cgttactgca agtattggtg cagcagctat
    23881 acttggagct cctattatgc atgatttctg tcatataagt ttgagtgatt taatgactcc
    23941 gtgggaagta attgaaaaaa gattgagatt ggctgctgaa gccgattttg taatttgttt
    24001 gtataatcca agaagtaagg gaagaagtga acatctaagc aaagcattca aaataatggg
    24061 tgagtttaaa ggtggagata cacctgttgg agtggtaaaa gatgtaggta gagaaaaaga
    24121 agaaaagttt gtatgtactt ttgaaaatat ggactttgaa aaagtcgata tgactacaat
    24181 ggttataata ggaaataagt ctacctatat taatggtgaa ttgatgataa ctccaagagg
    24241 ttatacagta tgattttaat tttaggagga acttcagata gtttatctat atgtgataag
    24301 ataaatgaac tgaaaaatca accatatatc ctttcagtta ctacagatta tggaagggaa
    24361 cttgcacaac aacatgcaga gaatgtaatt ttaggtaagc ttggaaaaga agatatgcta
    24421 aaatttataa aagataataa tatagtaaaa ataatagatg ccactcatcc ttatgcagtt
    24481 gaagtatcca aaactgctat tacttgtgca aaactattga atatagatta tataaggttt
    24541 gagagaaaat ctttaattga agaaatagat tatgataata aatttatagt agatacaatt
    24601 gaagaagcct gtgaaatagc aaataaaata gggacaaata tattcatagg aacaggaagt
    24661 aaaaatttga acagatttat agaggaaata agtgataaaa atttagttgt tagagttctt
    24721 ccaacgagtg aagtcatatt aagttgtgaa aaattaggtt taagtgcaga taatatagta
    24781 gctatgaaag gtccatttag ccagtatata aatgaagaaa catataaaca ttacaatata
    24841 gatttagtca taacaaaaga aagtggaata gctggtgggt tcttagagaa ggtaaatgca
    24901 tgtaaaactt tcaatatacc agtaataatt ataaaaagag aatcgattaa ctacgaaaat
    24961 gtatttaatg acataaataa aattaaagac atacttgtgt aatttttagg aggagaatat
    25021 atgaagaaag ccttattagt agtgagtttt ggtacaagct atcatgaaac gagagaaaag
    25081 acaatagata tatgtgaaga taaaataaaa aattcgttaa aaagccatga tttttttaga
    25141 gcttatacat caaatatgat aataaataaa ataaaaaaaa gggatggaat agaaatagat
    25201 aatccaatac aggctttaga taaaatatat gaacaaggat atgatgaagt aataatccaa
    25261 acacttcata ttatatgtgg cgaagaattt aacaaattaa aagaacaagt agatggatat
    25321 tcttctaaat tcaaaaagat tgtattagga agacctttgc ttacacatat tgaagattat
    25381 caggaagctg tagaggcaat taagcatcaa attcctcata tggaaagtaa tgaagcagta
    25441 gtatttatgg gacatggaac acttcatgaa tcacattcag cgtatccagc attggaatac
    25501 atgcttaggg ataatggaat aaatgcttat gttggtacag ttgaagggta tccagaaata
    25561 gaacatgtaa taagaagatt aaaagaagga aatataaaaa ctgtaaattt gatgccattt
    25621 atgttagttg caggagacca tgctataaat gatatggcag gagatgaaga agattcttgg
    25681 aaaacaatat tagaagaaaa tggatttaac gtaagagttc atttaaaagg actaggagaa
    25741 aattcttata tacaagataa atttgttcgt catgctgtaa aatgtgcaga gaatgcgaag
    25801 ttctatggta taggagcagg gccaggagat ggttctttac ttacgataaa agcggttaat
    25861 actttaaaga aactggatat tctatacact ccagaatcaa aaaagggtgg agatagtcta
    25921 gctttatcaa tagttagtga atatttacct gaatcagtgg aaataaagtc taggcatttc
    25981 ccaatgagtt ttgatgggaa tgaaaaaagt ttagcttggg acaatgtggc acaagaaatt
    26041 atatcagatg ttaatgatgg taaaaatgta ggatttgtta cattaggaga ccctatgatt
    26101 tatagtacat atgtatatat aatgaaaaga atattaggag aggtagaagt cgaaactata
    26161 ccaggaattt catcattttc caatatagca tctaatcaga attttccatt agtcatggat
    26221 aaagaagctt tagtggtaat tccttgtact atggaagatg ataagataga gtatgctttg
    26281 caaaattata attcaatagt attgatgaaa gtatataaaa attttaaaga aataataaaa
    26341 aaattagaaa agtatgattt aatagaacat gctattttag taagtaattc ttcccaagaa
    26401 agcgaaaatg tgtttacaga tttaaaagaa gcgcaccttg aagataagat atcttatttt
    26461 tctactatac tagtaaataa agataataaa ataaaatagg tgaaagcaat atttaaagga
    26521 gacttaatat gaatatagtg gttggaacta ggggtagtaa tctagcgctt atacaaacag
    26581 aatgggtaat aaatgaatta aaaaagaagt atccagaaat tagttttgag attaaaatca
    26641 taaagacaaa aggagattta attcaaaatg tttcactgga taaaataggt gataaaggat
    26701 tgtttgtcaa agaaatagag caacaattat tagatggaaa aatagacata gcagtacata
    26761 gtatgaaaga tatgccttct tatttagcag atggactaaa atttgctcat acgcctaaga
    26821 gagaagaccc aagagatgtt ctaatactta gagaaggata taaaaattta gatgatttgc
    26881 ctcatggagc agtaatagga acaggaagta aaagaaggaa gtttcaatta ttgaaacaaa
    26941 gacctgattt aaatatagta caagttagag gtaatgtgga aactaggata cgaaaaataa
    27001 aagatgaaaa catgcatggt attgtgttgg cagcatcagg aataattaga gctaatttac
    27061 aagataaaat aagttcttat ttacctgttg atgttgttat tccagcacct gcccaaggag
    27121 ctttagctat agaaattaga agcaatgata gtacgataga gggaatagta aattcactga
    27181 aggatgagaa tacagaaatc caaatattgg ctgaaagagg ttttttagat ggtgtaaatg
    27241 gaagttgtca tattccaata gcagcttatt gtgaaataat ccaagataaa atacatctta
    27301 ctggcttata tggagattca gaaggaaaaa aagtagtaat caagtctata gatggagata
    27361 tttcttctcc tagagagtta ggtttaaagt tagctaaact tgtattgaag gagtatgaga
    27421 attatgaagg gtaaggttta cttagtaggg gcaggaccag gtgattataa actcatgact
    27481 ttaaaaggtt tagagtgtat aagaaaatcg gatgtaatag tatatgatag attagcaaat
    27541 agtagttatt taagagaagc taagcctgat tgtgaactta tatatgtagg caaggcatca
    27601 agtaatcata ttttgccaca agaagatata aatagaatta tagcagaaaa agctaaagaa
    27661 ggaaaaattg taactcgtct taaaggagga gacccttatg tatttggcag agggggagaa
    27721 gaagcagaga ctttagtaga tgaaggtata gaatttgaag tagttccagg tataacttct
    27781 gctataggag gtttatgtta tgcgggtatt cctataacac atagagacca tgcttcgtca
    27841 tttcatgtaa taacaggtca tttgaagggt gatgatagtg gagaattaaa ctggaatgct
    27901 cttgcaaata acaaaggtac tcttgtgttt ttgatgggaa tttcaaacct agagaaaata
    27961 agtgaaaact taatgaaaga aggaaaagat aaggatacac ctgttgctct tataagttgg
    28021 gcaactagat ataatcaaag agttgttaca tctacacttg aaaatgttta tgaaactgct
    28081 attaaagaag aagtaaaacc gccaactctt atagtagttg ggagtgttgt aggacttaga
    28141 gaaaagttga acttctttga aagtaagcct ttatttggaa aaagtattgc tgtaactagg
    28201 tctagaaatc aaaatagtgt attggtagaa aaaataatgg atttaggtgg aaatcctata
    28261 gaaataccta ctattaaggt agaaaaaata caaaataata ttaacttaga aaatgaaata
    28321 aaaaatataa ataagtataa ttatctaata ctaactagta aaaatgccgt agaaatcttc
    28381 tttgaaaaga tatatgaaat gaattttgat ttaaggatat tatctaattt aaaggtatgt
    28441 gctataggtt ctgctacatc aaatgagttg aaaaaaagag gaattatagc ggatatagta
    28501 ccaaaaaaat ttgtagcaga gtcactgtat gaagagttag cgcctatttt aaatgatgac
    28561 gataatatac ttatacctag agcagaaaat gctagagatt atctagttga caaacttaag
    28621 gctatttgtg aagtaacaga agtacatata tatagaacag taatagatga ggagaaaaaa
    28681 ggtgagatat tagatatttt aaattctaat gacatagatt atataacatt tactagttcc
    28741 tcaacagtaa ataatcttgt tgaaattata ggaaaagaaa atattaaaat attagaaaaa
    28801 ataaaaacac tatctatagg tcctataact acagagacaa taaatagttt gggaataaaa
    28861 ttgtacaaag aatctgctac atctactata gattcgttag tagatttaat tataaaaaat
    28921 taattttgga ggcttgaata tgttaagaag accaagaaga ctaagagcaa gtaaagcaat
    28981 cagaaatttg gtaagagaaa ctaaggtgaa tgtagaagac ttaatatatc cactgtttgt
    29041 agtagagggg gaaaatataa aagaagaaat taaatcttta ccagatgtct atcatttatc
    29101 aatagatatg ctagaagacg aaataaaaga aataagtgag ttgggaattg aacatataat
    29161 gttatttggt gttccagatg aaaaagatga gtgtgcttca caagctttta atgataatgg
    29221 aatagttcaa aaggcaatta gaaaggtaaa agaaataaat tcagatataa atgtaataac
    29281 agatgtctgt atgtgccaat atacaagtca tggacattgt gggattttaa ctgatactgg
    29341 ttatgttgat aatgataaat cattggagta tttggctaaa atatctgtaa gccatgctaa
    29401 agcaggagct gatatggttg ctccatctga tatgatggat ggaagaatac aagcaataag
    29461 agaagcttta gatgaaaatg gattagaaaa tgttggaatc atggcttata gtgttaagta
    29521 tgcttcaaat tattatggac cttttagaga ggcagctcat tcagcaccat cttttggaga
    29581 tagaaaaaca tatcaaatgg acccagcaaa tagcaatgaa gctataatag agactgaact
    29641 tgatatattg gaaggtgcag atatacttat ggttaaacct gcattatcat atttagatat
    29701 tataagaaga gttaaagata attttgactt acctctagca gcttataatg taagtggaga
    29761 atactctatg cttaagtttg ctgtgaagga aggtttatta aatgaagatg taattcttga
    29821 atcaattaca tctataaaaa gagcaggagc agatataata ataacttatt ttgctaaaga
    29881 cattgctaaa ctgttgaaaa aataaattct agtagtataa agaatatcaa aaagtatagg
    29941 aattgtaatt aactattata cagtagtttt gtttagacat ttattgaaga ataatagaaa
    30001 ctaatttgca atttctatac tttatttatg taactaaata aaatttggag gtagaagatg
    30061 ctatatccta ttaatttaaa attagatgag ttagatgtag ttataattgg tggtggagaa
    30121 gttgcatata ggaaatgtaa aaatttctta gagtttaaca aaaatgttac tatagtttct
    30181 aaacaaattt taaataaatt ttatgattta aaaggaaata taaaaataat aaaagatgat
    30241 tataaagaaa tatatataaa agatgcttct gtaataattg ctgccacaaa taatagagag
    30301 ttaaatatgg aaataggatt atattgtaga gcaaaaaata agctagtgaa tgtagttgat
    30361 aatatagaaa tatcgaactt tactgttcca tcatatataa aaagaggaga tttacttata
    30421 agtgtgtcta ctgggggcaa gagtccttca ttatcatcaa agataaaaaa agaaattgaa
    30481 gagagatata ctgaagatta tgaggagtat ttaaatgtat taggagatat aagaaaaaag
    30541 gttataaaaa aatacgaaga taaaagtaaa agaaaagatg tgcttaatat gttggtaaca
    30601 cttgacctag aagaacttaa gaagtttgat atataaaaaa taaaataaaa aatgttaaaa
    30661 aggtgttgac ggat
//
LOCUS       DAMKNB010000041        29929 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.043, whole genome shotgun sequence.
ACCESSION   DAMKNB010000041 DAMKNB010000000
VERSION     DAMKNB010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 29929)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29929)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29929
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.043"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            132..272
                     /locus_tag="PC494_002109"
     CDS             132..272
                     /locus_tag="PC494_002109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3912609.1"
                     /translation="MGIIESASKLAEMVHLLAVEKGITDIEAWDEAVKEYSKIYEERR
                     NE"
     gene            complement(447..767)
                     /locus_tag="PC494_002110"
     CDS             complement(447..767)
                     /locus_tag="PC494_002110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like family protein"
                     /protein_id="HDF3912610.1"
                     /translation="MKLKTISLPELNNLDPTLESTFIKMGEEQGELAECIGKFRNLSG
                     ENNDLDEVDIIKKTAKELMDVAQTCVTMMFKLEEQYGINLDEIRKEHIKKLEKRGYIK
                     NMDK"
     gene            complement(887..1624)
                     /locus_tag="PC494_002111"
     CDS             complement(887..1624)
                     /locus_tag="PC494_002111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent protein deacylase"
                     /protein_id="HDF3912611.1"
                     /translation="MDANSLKDLIANHNNIVFFGGAGVSTESNIPDFRSSTGLFSQKL
                     NKQFTAEQLVSHTFFVRYPEEFFEFYKDKLIYPNAKPNNAHIALAKLEEMGKLKAVIT
                     QNIDGLHQMAGSKNVLELHGSVHRNYCTKCGKFFDLESMLNLGGNIPYCDNCGSIVKP
                     DVVLYEEALDSDVITKTISAISNADLLIIGGTSLAVYPAASFIDYYKGDYIALINKAN
                     TVYDKSASLVINKPIGEVLYEAVLRQI"
     gene            1839..3662
                     /gene="acd"
                     /locus_tag="PC494_002112"
     CDS             1839..3662
                     /gene="acd"
                     /locus_tag="PC494_002112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosaminidase"
                     /protein_id="HDF3912612.1"
                     /translation="MKKKAALATLAMLPLGVVNAHADGDIGIVTINYLNVRNEPTAES
                     SIAFVAKKDDKVLIKDSSNGWYKIKAESGQEGWASSKYIAKSNSDSLRTSTNKEKQVI
                     SNSLNMRNGAGTSYRVITVLKKGQKVEVISESNGWSKIKYDGRLGYVSSSYLGDVSNS
                     TNKSKTKQVNTTSLNVRSGPNTSYGLLGKLPKGSKVEVISESNGWSKIKYNGKDAYVS
                     SMYLSDVSQSNSDNSSQSNDKKNTDKVVNTASLNVRSGPGSTYSKLGKVYKGSKVTVL
                     SESSGWAKINFNNKEAFVVGNYLSTSADTSNNNSNSNSDNSSNSNGNNSSSSGQVNGM
                     SGISGAKIDYKSLSYTLESHISKQVEKAASGGNVIAPSNRKSTPSPEFSTFSAQRTSS
                     FVNASSSDIEYYLNPKNFTNTTKGMMQFLKINSYRDGISESSLNSYLNGLSSSVFKNQ
                     GAAFINAAKKYNIDVVYLVSHAMWETAYGKSTLAQGQTLTSYKGQPLSKPVKVYNFFG
                     IGAIDKSANVSGAEAAYSNGWTSVEATIDGSAKWISQNYVNSSKYNQNTIYKMKWNYD
                     YTWHQYATDVNWANGISGIMENLIGLYGGGSSLVFEVPQYK"
     gene            3877..8175
                     /locus_tag="PC494_002113"
     CDS             3877..8175
                     /locus_tag="PC494_002113"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HDF3912613.1"
                     /translation="MESIKEYLDKLEINNSGLGKQLKEVYINRVVYFKEDKIVYFYLT
                     SKDIVSHELLDKFKEELMYKLDYFKDMRMKIRFTGLERKSNKDVIKKYWNNILYILKY
                     LCPSIAGWYKQVEFLCLEEELKIKLPKGIFYERLMKKNVTYVLKTVLSEELGLDLNIT
                     IEKAVDEKVNKERLIRINDREMEEKIRALEIGKVNNCEENEEESYVIKSDVDENLIYG
                     DNANAMIENIVELNASSGTVAVVGDIFDVDTKELKNGKILMIASITDYTSSISCKLFL
                     TDTNKDGVLENVKKGAYLKIKGDIVYDTYQREISMMISGIRKETRIEREDKSEEKRVE
                     LHAHTQMSSMDAICSVKKLVERAAKWGHSAIAITDHGVVQGFPDAMNAGKSNNIKILY
                     GVEGYLVEDDSLIIEDANDKELSQTFVVFDIETTGFSNTNDKITEIGAVKIENFKIVD
                     RFSELINPEKDISYKIQELTGITNELIKDKPTIEEVLPKFMEFVGDSVLVAHNAEFDT
                     GFISQKCREQGLLYNNKKVDTLMLARVMLPNLKRHRLNVVAKELGIPLLNHHRAVDDA
                     EATALIFNKFLQMLTEKGAKTLSDVNNILGKIDYTKLSTNHITLIAKNSIGIKNLYKI
                     ISDAHVNHFFRAPRILRSVLNEYKEGLIIGSACEAGVVFQAVKKNVSDEEMKKIIDLY
                     DYIEVMPIDNNRFMIDKGEVKDEEELRELNRKLIDTAKKFDKIPVATGDVHFLDKHEA
                     VLRKVLKYSQGFKVDEEETYLHFRTTDEMLEEFSYLGEELAYEVVVENSNLIADMVED
                     IKPIPDDTYPPIIEGSDVELREMCYKKAKRIYGDPIPEIVQKRLDRELNSIISNGYAV
                     MYIIAQKLVAKSLSDGYLVGSRGSVGSSFAATMSDITEVNPLPAHYICENEDCKYSFF
                     YEIGEWGSGVDLPDKDCPKCGRKLAKNGHDIPFEVFLGFEGDKEPDIDLNFSGNYQPT
                     IHKYTEELFGEGYVYRAGTIGTVAEKTAFGYARKYVEENNISVPNAEVLRLSNGCTGV
                     KRTSGQHPGGVMVIPDYKDVYDFTPIQYPANDTSCGVITTHFDYHSISGRILKLDILG
                     HDGPTIIRMLEDMTGINITEIPLDDKETMSLFTSTEALGVTPEEINCPIGCLAVPEFG
                     TKFVRQMLLDTKPTTFAELVRISGLSHGTDVWVNNAQDLVREDIVGLKDVISTRDDIM
                     NYLIFKGLPPKMSFTIMESVRKGKGLKPEHIEEMKKNNVPEWYIGSCKKIKYMFPKAH
                     AVAYVMTSFRIAYCKVHYPEAFYATYFTTKVEDFDADLIVKGLDAIKSKINEIESLGN
                     DATTKEKGMLTVLEVALEMYARGIKLLPVDIYKSDATEFIVVGEKTLLPPMAAIQGLG
                     GNAAINIQNERKNGEFISKEDLRKRTKISKTVIETLTNHGSLENMSERNQLSLF"
     gene            8379..8840
                     /locus_tag="PC494_002114"
     CDS             8379..8840
                     /locus_tag="PC494_002114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HDF3912614.1"
                     /translation="MKKNLEATIEEIVTKITDEHGFEMVDVEYVKEAGEYYLRVYIDK
                     EEGISLNECELVSRELSPILDEKDPIKENYFLEVSSPGLDRALKKDRDFVRYQGRDVD
                     LKLYKPLNGCKQFEGELVGLTEDNNIKIIANGKEMEFNRKDVAIVRLAIKF"
     gene            8870..10024
                     /gene="nusA"
                     /locus_tag="PC494_002115"
     CDS             8870..10024
                     /gene="nusA"
                     /locus_tag="PC494_002115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HDF3912615.1"
                     /translation="MNHEFMEALDELVVDRGIDKEILIDTIEQALLTAYKKNFGSAQN
                     VRVEFDRDKGDIKVFSQRVVVDESDLYDTFLEIELADAREINPNYELGDIIEHEVTPK
                     NFGRIAAQTAKQVVVQRIREAEREIVYNEFIEKENEIVTGEVARANKNVVYVNLGRIE
                     GIMTQSEQIPFENYKAGQKIKFYILEVKKTNKGPQIVVSRSHPGLVKRLFEEEVPEIY
                     EGIVQIKSVAREAGSRTKMAVRSIDEKIDPIGACVGPKGLRVKNIVDELGDEKIDIIK
                     YSEDPAEFISAALSPSKVVRVDIDEDEKSALVIVPDYQLSLAIGKEGQNARLAAKLTN
                     WKIDIKSESQAEQEMLNLENSKEIEAEDVEAEFIDQEELDTSEDNFSEEE"
     gene            10031..10312
                     /locus_tag="PC494_002116"
     CDS             10031..10312
                     /locus_tag="PC494_002116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HDF3912616.1"
                     /translation="MILKKVKKVPQRKCIACQDRDSKKELIRIVKNKEGKIFLDPTGR
                     ANGRGAYVCKSSECLKKAIKSKALNKAFKIDVPDEVYDNLLMELEEYEK"
     gene            10302..10613
                     /locus_tag="PC494_002117"
     CDS             10302..10613
                     /locus_tag="PC494_002117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal L7Ae/L30e/S12e/Gadd45 family protein"
                     /protein_id="HDF3912617.1"
                     /translation="MKNNKEKVLSFLGLATRAGKIVSGDDSTLLDLKKGKVNLILIAE
                     DASNNTKKLFKDKSTFRNIPYLFFSTKEEIGFAIGKSPRAVVGIKDENFSKKIIELIE
                     I"
     gene            10635..12575
                     /gene="infB"
                     /locus_tag="PC494_002118"
     CDS             10635..12575
                     /gene="infB"
                     /locus_tag="PC494_002118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HDF3912618.1"
                     /translation="MSKTRVYQIAEELNISNEELINKLAELDINVTDKDSVLEGEELE
                     LALEMLGEDLSQENGNVIEIDGKLTVQVLATKLDKSPSEIIMKLMKMGTMATINQEIS
                     FEIAALAAKDYGFELTVAESDDTEALEIEALMEIEEDKEEDLKPRPPVVTVMGHVDHG
                     KTSLLDAIRKTDVISGEAGGITQHIGASEVKINGHKIVFLDTPGHEAFTSMRARGAQV
                     TDIAILVVAADDGIMPQTVEAINHAKAAGVPLIVAINKIDKPGANPDKVKQELADQGL
                     LVEDWGGEVIAVPVSAKKKEGIDTLLEMVLLVAEMEELRANPNKRAVGTVIEAELDKG
                     RGPVATVLVQGGTLTVGDPIVAGVACGKVRAMINAKGKRVKTAGPSTAVEILGLSEVP
                     QGGDQFVEVPTDKIARSVAARRQQIVRDEMLKSTQRLSLDALFSQMSEGSIKDLNIVI
                     KADVQGSVQAVKQSLEKLSNEEVQVKVIHGGVGAVTESDILLAAASNAIIIGFNVRPV
                     PGAESLGEKENVDIRTYTIIYKAIEDIQAAMTGMLDPEYVDEETGKAEIREIYKISGV
                     GTVAGCYVTNGKIFRNCKVRLVRDSIIIHEGELAALKRFKDDVKEVNSGYECGMSFVN
                     YNDIKEGDIVEAYITKEVERKL"
     gene            12618..12998
                     /gene="rbfA"
                     /locus_tag="PC494_002119"
     CDS             12618..12998
                     /gene="rbfA"
                     /locus_tag="PC494_002119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HDF3912619.1"
                     /translation="MASYNRTRRIAEEIRKVVSTMLINGVKDPRITSMVSVTDVEVTN
                     DLRYAYVYVSILGGDEESTLTGLKSAGGYIRREVGKNIKLRYIPEIVFKLDDSIEKGM
                     YMDSLIKRVNEKNAQQNEDENYDE"
     gene            12979..13962
                     /locus_tag="PC494_002120"
     CDS             12979..13962
                     /locus_tag="PC494_002120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HDF3912620.1"
                     /translation="MKIMMNNMDSIINYIYEGDYFIVTSHISPDGDNIGSTLSMYYTL
                     KNLGKNVYYVLDDEAPLNLRFLVEDVKIYKSNEFNMKNYSLIALDCGDKMRICVSDEI
                     KNNASKLICIDHHASNDSYGDLNYVDIDASSTCELVYNLLVRFQQIKDINIINEDIAT
                     CLYTGLVTDTGNFSYSNVHASSFEMAKNLLVLGAQKNTIIQNIYQSNSSGYYKLLGEA
                     LKGLEIFDSKVSSIVLTQDMMNRNNISFNDVDGITTYTRDIKGIEVGILFKEKKQNEI
                     KVSFRSKNYVDVSEIAKLFGGGGHVRAAGCTIRDSIDNAKKMVLEAVLKSI"
     gene            13975..14880
                     /gene="truB"
                     /locus_tag="PC494_002121"
     CDS             13975..14880
                     /gene="truB"
                     /locus_tag="PC494_002121"
                     /EC_number="5.4.99.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HDF3912621.1"
                     /translation="MNKIISILKPTGMTSHDVVSRVRKILNIKKVGHTGTLDPDASGV
                     LPICIGKATKVCEVILNKDKSYICELTLGISTDTYDASGEILKKVDDFKFSNEDIERA
                     FDTQRGEINQLPPIYSALKVNGKRMCDLVRSGRQSEITLKTRRVNIKDIKILSIKGNK
                     VMFYVECSKGTYVRSICHDIGEYLGCGAHMSFLNRTSSGKFDLDNSITLEELELFYEN
                     KTLDKYLYDIDYVLDSFNYVVLNPNAIKYYSNGGSIDDKRFLKNNFDKDDEFVRVYST
                     DNFLGLGKLSKHNNTISVKSDKMFI"
     gene            15011..15940
                     /locus_tag="PC494_002122"
     CDS             15011..15940
                     /locus_tag="PC494_002122"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional riboflavin kinase/FAD synthetase"
                     /protein_id="HDF3912622.1"
                     /translation="MVIIKSIKEIANIKESVITIGNFDGVHKGHQVLIGKTVEHAKKE
                     NIQSIVFTFANHPVNYFRPNSTKNIISNDDKIKLLEDLGIDIVVIIPFDEYMTKIPAK
                     DFVDEILVKKLKAKKIVIGHDFTFARAKEGNVNLLKSLEHEFGFEVEVIKPIKINDVR
                     VSSTYIRSLVSQGDMANVKEYLGRNYKLEGCVIHSKHLGRTIGFPTANIDLKNNMLVP
                     KRGIYASIVHIGDETYFGATNVGYNPTVNGKTLSIETNILEFDRDIYGENIIVEFLER
                     IRDERKFNSIDDLKNQLYNDTNYVYENYVCKNK"
     gene            16044..16301
                     /gene="rpsO"
                     /locus_tag="PC494_002123"
     CDS             16044..16301
                     /gene="rpsO"
                     /locus_tag="PC494_002123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002843739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HDF3912623.1"
                     /translation="MINKSEIIKEYGRAEGDTGSPEVQIALLTARINELNGHLKTHKK
                     DHHSRRGLLKMVGRRRNLLAYLKEKDLEGYRALIAKLGLRK"
     gene            16541..17386
                     /locus_tag="PC494_002124"
     CDS             16541..17386
                     /locus_tag="PC494_002124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HDF3912624.1"
                     /translation="MKIKLVCDSLCDIPDEISEKDYIEIVPLTVIFNDREYIEGVDIK
                     KEEFYKKVKEIKQIPKTSQATYMEFKEVFDKFITEGYHIICMTGAANASGTFQSAMIA
                     KNDVNENEKIHIFDTRNLSLGSGQYVIKACELLEEGLGFEEIIDELENTRSSVRLLFA
                     PYTLDFLKQSGRVPVATALIGNMLNIKPIFFFDNGEAKLVNKVRGIKNIASKLVDIIL
                     EMNEGSLEGKIVTIGCGDNLHDCEILKDEVNKRIKARRVLFTRGGVSICSHTGPDILA
                     ISCSN"
     gene            17511..19622
                     /gene="pnp"
                     /locus_tag="PC494_002125"
     CDS             17511..19622
                     /gene="pnp"
                     /locus_tag="PC494_002125"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HDF3912625.1"
                     /translation="MFEHKIFKMDFAGRELSVEIGKICEMASGSCIVRYSDSMVMVNT
                     TKSAKPRDGIDFFPLSVDYEEKLYSVGKIPGGFLKREGKPSEKAILTSRLIDRPIRPL
                     FPKGFRNDVQVVATVLSVDQDCTPDIVAMIGSSIALSISDIPFNGPTGSVCVGLVDGA
                     FVVNPNAEQREKSSMHLVVSGTKEAIMMVEAGADEVPDEVMLDAILFAHQEIKKIVEF
                     IEGIVAEVGKEKMPVELYHAGEEITQLVREFATDKMKKAVQTFEKLERMENMDRVKEE
                     TLAHFEETLEDFEDFVGDIEEVLQDIIKEEVRKLIVHENVRPDNRKLEEIRPIWCETG
                     MIPRAHGSAIFTRGQTQVLNVATLGALGDVQKLDGLDEEENKRYMHHYNFPAYSVGEA
                     RPSRGPGRREIGHGALAERALLPVIPSQEEFPYAIRLVSEVLSSNGSTSQASVCGSTL
                     SLLDAGVPIKDMVAGIAMGLIKHDGKVAVLSDIQGMEDHLGDMDFKVAGTEYGITAIQ
                     MDIKIDGIDKEILQRALKQAKEGRIHILGEMRKTISQPKPELSPYAPKIVKMQINPDK
                     IKDVIGPGGKIITKIIDETGVKIDIEQTGEVFISGIEIDMIKKAQELINNIVVEPEVG
                     KTYKGKVSRIMNFGAFVEILPGKEGLLHISHIAHERVAKVEDVLNIGDEVEVKVTEID
                     EKGRVNLSRKVLLPKPEHKNK"
     gene            19888..20631
                     /locus_tag="PC494_002126"
     CDS             19888..20631
                     /locus_tag="PC494_002126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HDF3912626.1"
                     /translation="MIMMVLNKSKLKKIIILILVVLLVLSGGVMVLKLFNNKPVFNLF
                     NGVDLPYERGTKDKSGYVALTCNIDLGWETEYVESILETLKKENVKITFNVTGKWAEK
                     NKDELLKIKKQGHEIGNHGYKHLDYSTLSYEDNYEQIETSKKIIEEIIGEKTKFFQAP
                     AGSFGPETVKAAKALGYTSIKWDADTIDWKYKDQPEVIIDRMKKKDIKDSSIILMHPT
                     NATTKCIDDIIAIVREKGLKPGKLSDVFK"
     gene            20789..22036
                     /locus_tag="PC494_002127"
     CDS             20789..22036
                     /locus_tag="PC494_002127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HDF3912627.1"
                     /translation="MYKTKILENGLTIIGEEIPYLKSITLGIWINAGSRIEEAQVSGT
                     SHFIEHMMFKGTKNRTSKEIASSIDNLGGQINAFTSKECTCYYVKLIDEHIDTGIDVL
                     SDMILNSKFDKNDIDKERLIILEELKMYEDSPDDLSYDLLVENIYANDGLGMNIIGTK
                     ESLYNITRESMLEYLNKYYIPNNAVISIAGNFNFDDMVEKIKSKFGHWEKKNLSIDIS
                     EAKFNPCFISKNKDTEQVNLAMCLKGIPFENDEEVYSMAVVNNIFGGSISSRLFQKIR
                     EEKGLVYSIYSSQTLYRKCGELGIFASMSTENLQDVYNLIKKEIENIRENYLTEKEIS
                     ESKEQLKGNYILDLESTSSRMMSTGKSMLLSKKVKTTDEILECINNVNINSIKKVVDK
                     VFNIENIGTCIVGRDVEKILHLD"
     gene            22071..22316
                     /locus_tag="PC494_002128"
     CDS             22071..22316
                     /locus_tag="PC494_002128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlmC/YmxH family sporulation protein"
                     /protein_id="HDF3912628.1"
                     /translation="MNLSEIAGKEIVNLVTGERLGVIGECDLILDETTGGILALLIPK
                     EKGFFARRKDKSFLEVPWRNVKKIGNDMIIIEYEGYI"
     gene            22326..23549
                     /gene="dapG"
                     /locus_tag="PC494_002129"
     CDS             22326..23549
                     /gene="dapG"
                     /locus_tag="PC494_002129"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HDF3912629.1"
                     /translation="MSILVQKFGGTSVESYEKMNEVCKIVKAYKKNDEELQLVLVVSA
                     MGRKGAPYATDTLINLCSAVNDEPSKRELDLIMSCGEIISGTILANLLNAQGIDSVFF
                     TGQQAGIITSDEYSNAKIKYINPKKVKRALDDGKVVVIAGFQGVTDDGEITTLGRGGS
                     DTSAVAIGKALECETVEIYTDVDGIMTADPRVEPNAKVLSFIDYEEVFQMADKGAKVI
                     HPRAVQLAKSGNITLAIKNTMNPTFEGTKIGSLCRHLEDNIEYEQERDFKVAVANKDS
                     VAQVKIKSAEEVFTEVLNEIEKKLITIDMINFFISEKAFVVEDADIKSLKEILDKFEL
                     DYEVNRDCAKVTLICSRIADEMSGIMSKVVRGLSKAGVSLLQTSDSNMTISCLVSEED
                     MHTAVHAIHQQFYLK"
     gene            23662..24396
                     /locus_tag="PC494_002130"
     CDS             23662..24396
                     /locus_tag="PC494_002130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease proteolytic subunit"
                     /protein_id="HDF3912630.1"
                     /translation="MKDYREDNERFDKDNCSEESSCEERECIKQFGTNEMPPQPPKDI
                     QCITIIGEIEGHFIGNPQKKATKYEHIIPMLYSIEESNDVKGVLVVLNTVGGDIEAGL
                     AIAELLNSTSKKVVTLVLGGSHSIGVPLATAGDYSFIAPTATMIIHPVRTTGLVIGIN
                     ETFEYFKKMQDRIIQFIIRTSNIKKDVLEKLMHEKDELVSDVGSVLIGKEAVDYGLID
                     EVGGLKEALKKLRELIKESEEEKNND"
     gene            24519..26930
                     /locus_tag="PC494_002131"
     CDS             24519..26930
                     /locus_tag="PC494_002131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HDF3912631.1"
                     /translation="MATKKKKKKKVNTLSFNAEYHNLITIFIGVFLLYSLNSNSMGWI
                     PVLMQNLFKGLFGGLSIAIPFIVIITGLLGFFDGNEYIYRLRKTKLYYIIILFIFVFY
                     GLLNAGTLPVDSPLKGNMFDDVMKLGVSGQGSGLIATTIAYYMSKIFGIAGGWLISIF
                     ALILSVMFIFNISIKDLVSNAKSKSKASKDSNLTFKDKIANMKKSAIDMMTDEVDDTT
                     INKKPGFFKGLMSKGLNNDDEEDEYFEEENSDGVDDKTIKIVGFNKAEDEYLEILEGT
                     QSMPELDVLKELQKATNENPVVDTKPEKKVDIAKPNLNIEKTQPMSIVAEPVNEDYSN
                     YKKPSIELLNKVNKKSDENGKKKVLKNASLLEKTLSDFGVEAKINQVTVGPTITRYEI
                     QPSPGVKVSKIVNLTDDIALSLAAKSIRIEAPIPGKSAIGIEVPNEEAQMVGVREVLE
                     SEEFNNFNSPLAMGLGKDVAGKIIIGDIGKMPHLLIAGSTGSGKSVCVNTLISSILYK
                     ANPDEVKLLLIDPKVVELANYNGIPHLLIPVVTDPKKAANALNWAVTEMNRRYKLFAD
                     AQVKDVTSYNEKAEEKLPKIVIIIDELADLMMASANDVEDYICRLAQMARAAGMHLIV
                     ATQRPSVDVITGVIKANIPSRIAFAVSSQTDSRTILDMGGAEKLLGKGDMLFYPLGAA
                     KPVRLQGAFISESESEKVIDFVKSQVKDGIKYEEDIIETISKVNTSKGSDEDEFLSEA
                     IEFVVESGQASASMLQRRFKIGFNRAARLIDSMEERGIIGASEGSKPRKVLISKQDLQ
                     NLEGE"
     gene            26933..27991
                     /gene="mnmH"
                     /locus_tag="PC494_002132"
     CDS             26933..27991
                     /gene="mnmH"
                     /locus_tag="PC494_002132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-selenouridine(34) synthase MnmH"
                     /protein_id="HDF3912632.1"
                     /translation="MSVIKIEKALKLDKVIFVDVRTEGEYEEDHILNAINMPLFKNNE
                     HNDVGTIYKMQGKHEAIQKGFDYVSYKLKDIYLQAAELALNYDNIVIYCARGGMRSGS
                     IVNLLSSLGVNVYQLEGGYKAYRNFVLEYLRHVMDTKNFVSVHGLTGTGKTDLLHLLD
                     EKGIDVLDLEGIAKNSGSTFGFITFDKKPPSQKNFETKLFESIFFSKENYIFVESESK
                     RVGSVTVPNEIFEAMTREGHHILLECDIENRVDRLCRDYIYDKDEGNILILKECINKF
                     RKRLGNKVVDDYIDLLESGEYKELVKRYLLEYYDPLYMHSVEKYKYSKIINFNDTQKA
                     LEDVIDLYESILEGESEC"
     gene            27985..29319
                     /gene="rimO"
                     /locus_tag="PC494_002133"
     CDS             27985..29319
                     /gene="rimO"
                     /locus_tag="PC494_002133"
                     /EC_number="2.8.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12 methylthiotransferase
                     RimO"
                     /protein_id="HDF3912633.1"
                     /translation="MLKIALESLGCSKNLVDAEIMMGILNNKGYKLIGDFEEADVIIV
                     NTCGFIESAKQESIDTIINFAELKKTGNLKLLIVTGCLAQRYSEELKTEIPEIDAIVG
                     TGSYQNIDKILKELSEMHKIVSLNDIEFVFNEDLPRYISTPSYMAYLKIGEGCSNNCT
                     YCIIPKLRGKYRSRKFEDIIKEAKKLAESGVKELVVIAQDTTKYGFDLYGKERLSELL
                     EELAKIDGFKWIRVMYSYPESITEELIQVIKKYDNICSYFDMPIQHASNNILKLMNRK
                     TTKEDILNKINLIRSNIPDAILRTTIIVGFPGETEDDFKQLVDFVEEVKFDRLGAFAY
                     SREEDTPADRLPNHIDEEVKIQRRDTLMMIQQKISEELNDKKIGKTYEVLIEEQIEDN
                     VYTGRTQGDAEEIDSIVYVKSVDNLEVGEFVSVQINDAMEYDLMGDVLYELA"
     gene            29306..29848
                     /gene="pgsA"
                     /locus_tag="PC494_002134"
     CDS             29306..29848
                     /gene="pgsA"
                     /locus_tag="PC494_002134"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HDF3912634.1"
                     /translation="MNLPNKLTLFRIFLIPVFVLIMLLNIPNKFLIACIIFIIASITD
                     ALDGKIARKYNLVTDFGKFMDPLADKLLVISALTCMIEDHLVSSWMVIIIVARELTVS
                     ILRAIAAADGKVIAAGNSGKLKTITQMVSIVFLLLGAQFENVLILNIGEILILIATLL
                     TLYSGWEYLYKNKELFMSSK"
BASE COUNT        12081 a         3183 c         5691 g         8974 t
ORIGIN      
        1 gtagatatat cctaattatg tcaaaaaata aaaaaatttt tatttattag agtttttgga
       61 aataataata acagatatta taattaatta acagtttttg taagtatttg acaatagaga
      121 gggtgtaaca aatgggaata atagagtcag catcaaaatt ggctgagatg gttcatttat
      181 tggctgttga aaaggggata actgatatag aagcatggga tgaagctgtg aaagaataca
      241 gcaaaattta tgaagaaaga agaaatgaat agaatgataa aaaatgaaaa cttgatgata
      301 aaaaataact ttatttaaag aaattcaatt tttatagaag tattaaaaat aatataaata
      361 aaaagatggt atttcaaatg taagtaaaaa atcattttgg gataccatcc ttattattta
      421 ttttaataat atataagtaa taaatcttac ttatccatat tttttatgta acctcttttt
      481 tctagctttt ttatatgctc cttacgtatt tcatcaagat taataccata ttgttcttct
      541 agcttaaaca tcatagtaac acatgtctgc gctacatcca ttagttcctt agcagttttc
      601 tttataatat caacttcatc taaatcatta ttttctccac ttagatttct gaatttacct
      661 atacattcag ctaattcacc ttgttcttca cccattttga taaatgtaga ttctagtgtt
      721 gggtctaaat tattaagctc tggtaaagat atagttttta gtttcataaa agctcctttc
      781 aagttattcg tatttatact aaaacatcat aacaaaaata atactaaaaa aaaactttaa
      841 attcaacata aaaacttaca tatataataa aaatcgtgaa ataaatctat atttgtctta
      901 atacagcctc atataaaact tctccaatag gtttatttat tacaagagaa gctgacttat
      961 catagactgt atttgcttta ttaataagag caatataatc acctttgtaa taatctataa
     1021 aacttgctgc tgggtacaca gctaatgatg tacctcctat aatcaataaa tcagcattac
     1081 ttatagcaga aattgtttta gtaatgacat cactgtcaag agcttcctca taaagtacta
     1141 catctggttt tactatagaa ccacagttgt cacagtaagg aatattacct cccagattta
     1201 acatagattc taagtcaaaa aacttaccac atttagtaca ataatttcta tgtacagaac
     1261 catgaagttc tagcacattt ttacttccag ccatttgatg aagtccatca atattttgag
     1321 ttatgacagc tttaagctta cccatttctt cgagttttgc taaagctata tgagcattat
     1381 tgggttttgc attaggatat attaatttat ccttataaaa ttcaaaaaat tcttctggat
     1441 atctaacaaa aaaagtatgt gaaactaatt gttcagcagt aaattgttta ttgagttttt
     1501 ggctaaataa tccagtagaa cttctaaagt ctggaatatt agattcagtt gaaacacctg
     1561 ctccaccaaa aaatacaata ttattgtgat tagctattaa gtcttttaag ctatttgcat
     1621 ccatagttac acctccaaat tattatatat aaattgtact acatattagg tcgtttatgt
     1681 tttattaatt taaataaata tatagtttaa taagttaaat aaagggaata taaataaaat
     1741 gtatacagag tataaataga caatatttac taaaataaca agttgtcgta taattatatt
     1801 aaaattgttt tagtgtataa gaagggcggg ggaagtacgt gaagaaaaaa gcagctttag
     1861 caacattggc tatgttaccc ttaggtgtgg taaatgcaca tgctgatgga gatataggta
     1921 tagtgactat aaattattta aatgtaagaa atgaaccaac tgccgaaagt agcatagcct
     1981 ttgttgctaa aaaagatgat aaagttttga ttaaagactc ttctaatgga tggtataaaa
     2041 taaaagctga atctggacaa gaaggttggg cttcatcaaa atatatagca aaatcaaata
     2101 gtgactcttt aagaacgtct acaaataaag aaaaacaagt tatttcaaat agtttaaata
     2161 tgagaaatgg agcaggtaca agttacagag taataactgt actaaaaaaa ggtcaaaaag
     2221 tagaagtaat atcagagagt aatggatggt ctaaaatcaa atatgatgga agactaggat
     2281 atgtatctag ctcttattta ggagacgttt caaactcaac taataaatca aaaactaaac
     2341 aagtgaatac aacttcacta aatgtaagga gtggaccaaa tacaagttat ggtttgttag
     2401 gcaagttgcc aaaaggaagt aaagtagaag taatatcaga aagtaatgga tggtcaaaaa
     2461 taaagtataa tggaaaagat gcctatgtat ctagtatgta cttatcggat gtaagtcaaa
     2521 gtaattcaga caattctagt caaagcaatg ataaaaagaa tactgataag gttgtaaata
     2581 cagcttcttt aaatgtaaga agtggaccag gttctacata tagtaagttg ggaaaagttt
     2641 ataaaggaag taaagtaact gtactatcag aaagtagtgg atgggctaag attaatttta
     2701 acaataaaga agcatttgta gtaggcaatt atttatctac ttcagcagat acttcaaata
     2761 ataactcaaa tagtaactct gataacagtt ctaatagtaa tggtaataat tcttcatcat
     2821 caggtcaagt aaatggtatg tcaggtataa gtggggctaa aattgattat aaatctttga
     2881 gttatacttt agaatctcat ataagtaaac aagttgagaa agcagcatca ggaggaaatg
     2941 tgatagctcc aagtaatagg aaaagtactc caagtcctga atttagtact ttttcagctc
     3001 aaagaacaag ctcatttgta aatgcaagtt caagtgatat agaatattat ttaaatccta
     3061 agaattttac aaatactact aaaggtatga tgcagttttt aaagattaac agttatagag
     3121 atggtatttc agaatcaagt cttaactcgt atcttaatgg tttatcttct agtgtattta
     3181 aaaatcaggg agcagctttt ataaatgctg ccaagaagta taatatagat gttgtatatc
     3241 tagtatctca tgctatgtgg gaaactgctt atggtaagtc tacacttgcc caaggtcaaa
     3301 cattaacatc ttataaggga caacctctta gtaagccagt taaagtatac aatttttttg
     3361 gtataggagc aatagataaa agcgctaatg tttcaggtgc agaagcagcg tattccaatg
     3421 gctggactag tgtagaagct acaatagatg gctctgcaaa gtggatatca caaaattacg
     3481 taaatagttc taagtacaat cagaatacta tctacaagat gaagtggaat tatgattata
     3541 catggcatca gtatgcaact gatgtaaact gggctaatgg aatttctgga attatggaaa
     3601 atttaattgg tctttatgga ggaggaagta gtttggtttt tgaagttcct caatataagt
     3661 aatacataaa taaaaaatat agactatggg tagttttcat tttatttaaa ttatctatag
     3721 tctttttgta tataatttat aatctgtaaa ttcaatgtta acaaaacttt tatgttataa
     3781 tattaattct aagtaaatat aagtgagtaa taggtagaaa tagataaaaa gtggtaataa
     3841 tatatataaa gataattttg agaaaggagg atatatatgg aaagtattaa ggaatatttg
     3901 gataagttag aaattaataa tagtggtctt ggaaagcaac ttaaagaagt ttatataaat
     3961 agagtagttt attttaagga agataagata gtttattttt atctaacttc taaagatatt
     4021 gtttctcatg aacttttaga taaatttaaa gaagaattga tgtataaact cgattatttt
     4081 aaagatatga ggatgaagat aagatttact ggtcttgaaa gaaaatccaa taaagatgtt
     4141 ataaaaaaat attggaataa tatattgtat atattaaagt atctttgtcc atctattgca
     4201 gggtggtata aacaagtaga atttctttgt ttagaagaag aattaaaaat aaaacttcca
     4261 aaaggtatat tttatgagcg attaatgaaa aaaaatgtaa cttatgtact taaaaccgtg
     4321 cttagcgaag agttgggatt agatttaaat ataacaatag aaaaagctgt tgatgaaaag
     4381 gtaaataaag aaagactcat aagaatcaat gatagagaaa tggaagaaaa aattagggct
     4441 ttagaaattg gaaaagttaa taactgtgaa gaaaatgaag aggaaagcta tgtcattaag
     4501 tctgatgtag atgaaaattt aatctatgga gataatgcaa atgctatgat tgaaaatata
     4561 gttgaattaa atgcatcttc tggaacagtt gcagttgttg gagatatatt tgatgttgac
     4621 actaaagaac ttaaaaacgg aaaaatactt atgatagctt caattacaga ttatactagc
     4681 tcaataagct gtaaactttt tttaacagat acaaataagg atggagtact tgaaaatgtt
     4741 aaaaaaggag catacttaaa aatcaagggt gacatagttt atgatacata tcaaagagaa
     4801 attagtatga tgattagtgg gataagaaaa gaaactagaa tagagagaga agataaatca
     4861 gaggaaaaaa gagtagaact ccatgcacat acacaaatgt cttctatgga tgctatttgt
     4921 tctgttaaaa agcttgtaga gcgtgcagcc aaatggggtc attctgctat tgctataaca
     4981 gaccatggtg ttgtacaagg atttccagat gctatgaatg caggtaagtc aaataatata
     5041 aaaatacttt atggagtaga agggtacttg gttgaagatg attctctcat tatagaggat
     5101 gcaaatgata aagaactttc acagacattt gttgtatttg acatagagac aactggtttt
     5161 tctaatacaa atgataaaat aactgagatt ggtgctgtaa aaatagaaaa ctttaagatt
     5221 gtagatagat ttagtgagtt aataaatcct gaaaaagata tttcttataa gatacaggaa
     5281 ttgacaggaa taactaatga attaattaaa gacaagccaa ccattgaaga agttcttcct
     5341 aagtttatgg aatttgttgg agatagtgta ttagtagcac ataatgcaga gtttgatact
     5401 ggatttatat cgcaaaaatg tagggaacaa ggcttgttat ataataacaa aaaagtagat
     5461 acacttatgt tagcaagagt aatgttgcca aacttaaaaa gacatagatt aaatgtcgtt
     5521 gcaaaagaac ttggtattcc tcttttaaat caccatagag cagtggatga tgctgaagct
     5581 acagcactta tatttaataa gtttttgcag atgcttacag aaaaaggtgc aaaaactcta
     5641 agtgatgtaa acaatatact tggaaagatt gattacacaa agcttagcac aaatcatata
     5701 accttgatag caaaaaattc tataggtata aaaaatttat ataaaataat ttcagatgca
     5761 catgtaaatc atttttttag agcaccaaga atccttagaa gtgtattaaa tgaatataaa
     5821 gaaggattaa taattggttc ggcttgtgaa gctggggtgg tttttcaagc tgtaaagaaa
     5881 aacgtgtctg atgaggaaat gaaaaaaata atagatttat acgattatat tgaagtaatg
     5941 cctatagata ataatagatt tatgattgat aaaggagaag taaaggacga agaagagtta
     6001 agggagttga ataggaaatt aattgataca gccaaaaaat ttgacaaaat tccagtagct
     6061 actggggatg ttcatttttt agacaaacat gaagctgtct taagaaaagt tcttaaatat
     6121 tctcaaggtt ttaaagtaga tgaagaagaa acttatttac attttagaac aacagatgaa
     6181 atgttggaag agtttagtta tcttggagaa gaattggcat atgaagttgt agttgaaaat
     6241 agtaatctga ttgccgatat ggttgaagat ataaaaccta taccagatga tacttatcct
     6301 ccaattatag agggctcaga tgtggagtta agagaaatgt gttacaaaaa agccaaacga
     6361 atctatggag acccaatacc agaaatagtt caaaaaagac tggatagaga attaaattca
     6421 ataataagca atgggtatgc agttatgtat attatagctc aaaaactggt tgcaaaatct
     6481 ctttcagatg gatatttagt tggttcaaga ggctcagttg gctcatcttt tgcagctact
     6541 atgagtgata taacagaagt taatcctctt ccagcacatt atatttgtga aaacgaagac
     6601 tgtaaatatt cattctttta tgaaataggt gaatggggct caggtgttga tttaccagac
     6661 aaggattgtc caaagtgtgg aagaaaactt gctaaaaacg gtcatgatat tccatttgag
     6721 gttttcttag gttttgaagg tgataaagaa ccagatatag acttaaattt ctcaggaaat
     6781 tatcagccaa caattcataa atacacagaa gaactatttg gagaggggta tgtatatagg
     6841 gctgggacta taggtactgt agcagaaaaa acagcttttg gatacgcaag aaaatatgtg
     6901 gaagaaaata atataagtgt accaaatgca gaagtactta ggctttcaaa tggatgtact
     6961 ggagtaaaaa gaacctcagg acaacatcct ggtggagtta tggttatacc agactataaa
     7021 gatgtatacg attttacacc tatacagtat ccagcaaatg atacttcttg tggtgttata
     7081 actactcact ttgattatca ttcaataagt ggtagaatac ttaaacttga tatacttgga
     7141 cacgacggtc ctaccattat aaggatgctt gaagatatga ctggaataaa tataacagaa
     7201 attcctttag atgataaaga gactatgtct ctatttacat ctacagaagc attaggtgtt
     7261 acaccagaag aaataaactg tcctataggt tgccttgctg taccagagtt tggaactaag
     7321 tttgtacgac aaatgttact tgacacaaaa cctactacat ttgcagaact tgtacgtata
     7381 tctggtctct ctcatgggac agatgtttgg gtaaataatg cacaagactt agttagagaa
     7441 gatatagttg gattaaaaga tgttatatct acacgagatg acataatgaa ctatttaata
     7501 tttaaaggat tacctcccaa aatgagcttt acaataatgg agagtgtaag aaaaggtaaa
     7561 ggtttaaaac cagaacacat tgaagaaatg aaaaaaaata atgttccaga atggtatata
     7621 ggctcatgta aaaagattaa gtacatgttc ccaaaagcac atgctgttgc ttatgtaatg
     7681 acatcattta gaattgcata ttgtaaagtt cactatccag aagcatttta tgcgacttat
     7741 tttacgacaa aagttgagga ttttgatgca gatttaattg ttaaaggatt agatgctata
     7801 aaatcaaaaa taaatgaaat tgagtcactg ggaaatgatg caaccacaaa agaaaaaggt
     7861 atgttgaccg ttttagaagt tgctcttgaa atgtatgcta gaggaataaa attattacca
     7921 gttgatatat ataaatcaga tgcaactgag tttatagttg taggagaaaa aacattactt
     7981 ccaccaatgg cagcaataca aggtcttgga ggaaatgcgg ctataaacat ccaaaatgaa
     8041 agaaaaaatg gtgaatttat atcaaaagaa gatttgagaa agagaacaaa aatatcaaaa
     8101 acggtaatag aaactcttac taatcatggt tcacttgaga atatgagtga gagaaatcaa
     8161 ttgtcattgt tttaagttag cccaaaaagt tgcaaataaa agaattttat gatatcatag
     8221 tatagaaaat agtatacttt gcagaaacta agagtgagac agctgttctc actcttttat
     8281 tttaaatata ttattaaaaa gctggtttat ttttattaaa tatattttat ttaagattat
     8341 ataaactggt catttacaat tgaataggag gaactttaat gaaaaaaaat ttagaagcta
     8401 caattgagga gattgtaact aaaataacgg atgaacatgg atttgaaatg gttgatgttg
     8461 aatatgtaaa agaagcagga gaatactact taagagtata catagataaa gaagaaggaa
     8521 tatctttaaa tgaatgtgaa ttagttagta gagaattaag tccaatacta gatgaaaaag
     8581 accctataaa agaaaattac tttttagagg tatcttctcc agggcttgat agagcattaa
     8641 aaaaagacag agattttgtt agatatcaag gtagagatgt agatttaaaa ttatataaac
     8701 cattaaatgg atgtaagcaa tttgaaggtg aacttgtagg attaacagaa gataataata
     8761 taaaaatcat tgcaaatggt aaggaaatgg aatttaatag aaaagatgtt gctattgtca
     8821 gattagcaat aaagttttag tggtatatta aatagggagg atataaaaaa tgaatcatga
     8881 atttatggaa gcattagatg aattagtagt tgacagaggt atagataaag aaatacttat
     8941 agatactata gaacaagctc ttttaactgc atacaagaaa aactttggtt cagcacaaaa
     9001 tgttagagtt gaatttgata gagacaaggg agatataaaa gtattttctc aaagagttgt
     9061 tgttgatgaa tcagatttat atgatacttt cttagaaata gagttagcag atgctagaga
     9121 gataaaccct aattatgaat taggtgatat tatagaacat gaagttacac ctaaaaactt
     9181 tggaagaatt gcagctcaaa cagcaaagca agtagttgtt caaagaataa gggaagctga
     9241 gagagaaata gtgtataatg aatttataga aaaagaaaat gaaatagtta caggagaggt
     9301 tgctagagca aataaaaatg ttgtttatgt aaatcttgga agaatagaag gtataatgac
     9361 tcaaagtgaa caaataccat ttgagaatta taaagcaggt caaaaaataa aattctatat
     9421 acttgaagtt aaaaagacta acaaaggacc tcaaatagtt gtatcaagaa gtcatccggg
     9481 tctagtaaag agattgtttg aagaagaagt tcctgaaata tatgaaggaa tagttcaaat
     9541 aaaatctgta gcaagagaag cagggtcaag aactaaaatg gcagtaagat ctatagatga
     9601 aaaaatagac ccaattggag cttgtgttgg accaaaagga cttagagtaa aaaatatagt
     9661 ggatgaactt ggcgatgaga aaatagatat aataaaatat agtgaagacc cagcagagtt
     9721 tatatcagca gcacttagcc catcaaaggt tgttagagta gatatagatg aagatgaaaa
     9781 gtctgcctta gtaatcgttc cagattatca gttatcgctt gctataggta aagaaggtca
     9841 aaatgcaaga ctagcagcaa aattgactaa ctggaaaata gatattaaga gcgaatctca
     9901 agcagaacaa gaaatgttaa atcttgaaaa ttccaaagaa atagaagctg aggatgttga
     9961 agctgaattt atcgaccaag aagagttaga tacttcagag gataatttta gtgaagaaga
    10021 gtaaggaggg atgattttga aaaaagtaaa aaaagtgcct caaagaaaat gcatagcatg
    10081 tcaagataga gactctaaaa aagagcttat aagaatagtt aaaaataaag aaggaaaaat
    10141 atttttagac ccaacaggaa gagccaatgg aagaggagca tatgtatgta aaagctctga
    10201 atgtctaaaa aaagctataa agagtaaagc attaaataaa gcttttaaaa tagatgttcc
    10261 tgatgaagtc tatgataatc tacttatgga gttagaagaa tatgaaaaat aataaagaaa
    10321 aagtactttc gttcttaggg ctcgcaactc gtgcagggaa aatagtgtct ggtgatgatt
    10381 caactttgct tgaccttaaa aaaggaaaag taaatttgat tttaatcgca gaagatgcat
    10441 caaataatac taaaaaactt tttaaagata aatcaacttt tagaaatatt ccatatctat
    10501 ttttttcaac aaaagaggaa ataggatttg caataggaaa atctccaaga gcagttgtag
    10561 gaataaaaga tgaaaatttt tctaaaaaga taattgaact aatagaaatt taaaataaaa
    10621 tagggggtga tcttgtgtca aaaacaagag tataccaaat agcagaagaa ttaaatatat
    10681 caaatgaaga gcttataaat aagttagctg aattagatat aaatgtaact gacaaagatt
    10741 cagtattaga aggtgaagag ttagaattag cacttgaaat gttaggtgaa gatttatctc
    10801 aagaaaatgg aaatgttata gaaatagatg gaaagttgac agtacaagta ttagcaacga
    10861 aattagataa atctccatca gaaataatta tgaagcttat gaaaatggga actatggcaa
    10921 caataaatca agagataagt tttgagattg ctgctttggc tgccaaagac tatggatttg
    10981 aattaacagt agctgaaagt gatgatacag aagctttaga aatagaagct ttaatggaaa
    11041 ttgaagaaga taaagaagag gatttaaaac ctagaccacc agttgttaca gttatgggac
    11101 atgttgacca tggtaagaca tctttactag atgcaataag aaaaactgat gtgatttcag
    11161 gtgaagctgg aggaataact cagcatatag gtgcttcaga agttaaaatc aatggacaca
    11221 aaatagtatt tttagatact ccaggacatg aggctttcac atcaatgaga gcaagaggag
    11281 cacaagttac agatatagca atattagtag ttgcagcaga tgatggtata atgcctcaaa
    11341 cagttgaagc tataaaccat gctaaagcag caggtgtacc tttaatagtt gctattaata
    11401 aaatagataa accaggtgca aacccagata aggttaaaca ggaattagca gaccaaggat
    11461 tattagttga agactggggt ggagaagtaa tagcagttcc agtatcagct aagaaaaaag
    11521 aaggaataga tacactttta gaaatggtat tattggttgc tgaaatggaa gagttaagag
    11581 ctaatccaaa taaaagagca gtaggaactg ttatagaagc tgagcttgat aaaggaagag
    11641 ggccagttgc aacagtactt gttcaaggtg gtactttaac agtaggtgac ccaatcgttg
    11701 caggtgttgc atgtggtaaa gttagagcaa tgataaatgc aaaaggtaag agagtaaaaa
    11761 cagcaggacc atctacagca gtcgagatat taggtctatc agaagttcca caaggaggag
    11821 accaatttgt cgaagttcca actgataaga ttgctagaag tgtagcagca agaagacaac
    11881 aaatagttag agatgaaatg ttaaaatcaa ctcaaagatt atcactagat gctctattta
    11941 gtcaaatgag tgaaggttct ataaaagacc ttaatatagt tataaaagca gatgtacaag
    12001 gttcagtaca ggcagttaaa caatctttag aaaaattatc aaatgaagaa gttcaagtta
    12061 aagtaataca tggtggtgtt ggagctgtaa cagaatcaga catattactt gcagcagctt
    12121 ctaacgcaat aataatagga ttcaatgtaa gaccagttcc aggtgcagaa tctctaggag
    12181 aaaaagaaaa tgttgatata agaacatata ctataatata caaggcaata gaagatatac
    12241 aagcggctat gactggtatg ttagaccctg aatatgttga tgaagaaaca ggaaaagctg
    12301 aaataagaga aatatataaa atatctggtg ttggaacagt agctggatgt tatgtgacta
    12361 atggtaagat atttagaaat tgtaaagtaa gattagttag agatagcata ataatacatg
    12421 aaggtgagct tgcagcactt aagagattta aagatgatgt aaaagaagtt aattctggat
    12481 acgaatgtgg tatgagtttt gtaaattata acgacataaa agaaggcgat atagtagaag
    12541 cttatataac taaagaagta gaaagaaaat tataaattcg tatcaaagaa aatcagttag
    12601 taaagaaggt cgatggtatg gcatcatata atagaacaag aaggatagca gaagaaataa
    12661 gaaaagtcgt aagcactatg cttataaatg gagtaaaaga ccctagaata acatctatgg
    12721 tgagtgtaac tgatgtagaa gttacaaatg acctaagata tgcttatgta tatgtaagca
    12781 ttctaggtgg agatgaagaa tccacactaa caggtcttaa aagtgctgga ggatatataa
    12841 gaagagaagt aggaaaaaat ataaaactta gatatattcc tgaaatagta tttaaacttg
    12901 atgattcaat agaaaaagga atgtatatgg atagccttat aaaaagagtt aatgaaaaaa
    12961 atgctcaaca aaatgaggat gaaaattatg atgaataata tggatagtat tataaactat
    13021 atttatgagg gtgactattt tatagttacc tctcatatca gtccagatgg agacaatatt
    13081 ggttctacac tttcaatgta ttatacattg aagaatttag gaaaaaatgt atattatgta
    13141 cttgatgatg aagctccatt aaatttaagg tttttggttg aagatgtaaa aatctataag
    13201 tctaatgaat ttaatatgaa gaactattct ctaattgcac ttgattgtgg ggataagatg
    13261 agaatatgtg tgagtgatga aatcaaaaat aatgcatcaa aattaatctg tattgaccat
    13321 catgctagta atgattcata tggagattta aattatgtag atattgatgc atcttctaca
    13381 tgtgaattag tttataattt attagttaga tttcagcaaa taaaagatat taatattata
    13441 aatgaagata tagcaacatg tttatataca ggtcttgtaa ctgatactgg aaacttttcg
    13501 tattcaaatg tacatgcaag tagctttgaa atggcaaaaa atttacttgt tttaggtgca
    13561 caaaaaaata ctataataca aaatatatat caaagcaatt cttctggtta ttacaaatta
    13621 ttaggagaag ctctaaaggg tttggagata tttgattcaa aggtatctag tatagtttta
    13681 actcaagaca tgatgaatag aaataatatt agctttaatg atgttgatgg aataacaaca
    13741 tatacaagag acataaaagg tatagaagtt ggaattttat ttaaagagaa aaaacaaaat
    13801 gaaattaaag tgagttttag gtcaaaaaat tatgttgatg taagtgaaat agccaagtta
    13861 tttggtggtg gtggtcatgt aagggctgct ggatgtacta ttagagatag tattgataat
    13921 gcaaagaaaa tggtactaga ggcagtgtta aaatcaattt aaggtgacag taaaatgaat
    13981 aagattataa gtatattgaa acccacaggt atgacatctc atgatgttgt aagtagagtg
    14041 agaaagattt taaatataaa aaaagttggt catacaggta ctcttgaccc agatgcttca
    14101 ggtgttttac caatctgtat agggaaagct acaaaagtat gtgaagttat tttaaacaaa
    14161 gataaatcgt atatatgtga gcttacttta ggtataagta cagatactta tgatgcttca
    14221 ggtgaaattt taaaaaaagt tgatgatttt aaatttagta atgaagacat agaaagagct
    14281 tttgacacac aaagaggaga gataaatcaa cttcctccaa tttattcagc tttaaaggta
    14341 aatggaaaga gaatgtgtga tttagtaaga agtggtagac aatctgaaat tactttaaaa
    14401 acaagaagag taaatataaa agacataaaa atactaagta taaaaggtaa taaagtaatg
    14461 ttttatgttg agtgttctaa agggacttat gtgagaagta tttgccatga tataggagaa
    14521 tatctaggtt gtggagctca tatgtcgttt ttgaatagaa catcttctgg taaatttgac
    14581 ttagataatt caataacatt agaagaatta gaattatttt atgaaaataa aactttagac
    14641 aaatacttat atgatataga ttatgtcctt gattcgttta attatgttgt attaaaccct
    14701 aatgctataa aatattatag taatggtggc tcaatagatg ataaaaggtt tttaaagaat
    14761 aatttcgata aagatgatga atttgtaaga gtatacagta cagataattt cttaggatta
    14821 ggaaagttat caaaacacaa taatacaata agtgttaaaa gtgataagat gttcatataa
    14881 ccaatgtatt taaaaaaaca acaaaagaga tagtactata ataacttcta tagtctatct
    14941 cttttactta tgctataata gtttgtgaat aagttaagag taaattatat tttagcgggg
    15001 aacatttatt atggtgatta taaaatctat aaaagaaata gcaaacataa aagaaagtgt
    15061 cattaccata ggaaattttg atggtgtaca caaaggacat caagttctta taggaaaaac
    15121 agttgaacat gcaaaaaaag aaaatataca gagtattgta tttacatttg caaatcatcc
    15181 tgtaaattac tttagaccaa actcaacaaa aaatattata agcaatgatg ataaaataaa
    15241 attattagaa gatttgggaa tagatatagt tgtaatcata ccatttgatg agtatatgac
    15301 taaaatacct gcaaaggatt tcgtagatga gatactagta aaaaaattaa aagctaaaaa
    15361 gatagtaatt ggacatgact ttacatttgc aagggcaaaa gaaggcaatg ttaatctatt
    15421 aaaaagctta gaacatgaat ttggttttga ggtagaagta ataaaaccca tcaaaatcaa
    15481 tgatgtaaga gtgagtagta cttatattag aagtttagta tcccagggtg atatggctaa
    15541 tgtcaaggaa tatttgggta gaaattacaa gttagaaggt tgtgttatac attctaaaca
    15601 ccttggaaga actataggat tcccaacggc aaatattgac cttaagaata atatgctcgt
    15661 tccaaagaga ggtatttatg cttctattgt acatattgga gatgagactt attttggtgc
    15721 tacaaatgta ggctataacc caacagttaa tggaaaaact ttgtctattg aaacaaatat
    15781 tttagagttt gatagagata tttatgggga aaatataatt gttgaatttt tggaaagaat
    15841 aagagatgaa agaaagttta attcaataga tgacttaaaa aatcaattgt ataatgatac
    15901 aaattatgtg tatgaaaact atgtttgcaa aaacaagtaa tgtatgataa aatgattaag
    15961 gaaaataacc attactcggc atttgaatac tccaatcaat gcttagtaat aggcgtttct
    16021 aaaaaaatac ggaggtaatc taaatgataa acaaatcaga aataataaaa gaatatggaa
    16081 gagctgaagg ggatactggt tctccagaag tacaaatagc tttattaaca gctagaataa
    16141 acgagttaaa tggacattta aaaactcata agaaagacca ccattcaaga agaggactat
    16201 taaaaatggt tggtagaaga agaaacttat tagcttactt aaaggaaaaa gatcttgaag
    16261 gatatagagc attaatagct aaattaggat taagaaagta atttcattct ttataaaaaa
    16321 gcaggtatag tgtatacctg cttttttata gttaattcat tataaagtaa aatagttaat
    16381 aataaaagta gtttatatgt tataaaaaat tataaaatga ataatattgg gtaagaatat
    16441 taaaatagta tacaaataca taatcaattt aaaaggaaag acaggataaa tatagaaatt
    16501 ttataacagg ataattagtt ggaataagga ggatattatt ttgaaaataa agttagtatg
    16561 cgatagtttg tgcgatattc cagatgaaat atcagaaaaa gattatatag agatagttcc
    16621 acttacagtt atttttaatg atagggaata tatagaagga gtagatataa agaaagaaga
    16681 gttttataaa aaagtaaaag aaatcaagca aatacctaaa acttcacaag ctacatatat
    16741 ggagtttaaa gaagtgtttg ataagttcat aacagaaggt tatcatataa tctgtatgac
    16801 aggggctgca aacgcatcag gaacttttca aagtgctatg atagctaaaa atgatgtaaa
    16861 tgaaaatgaa aaaatacata tatttgatac tagaaattta tctctaggta gtggacaata
    16921 tgttataaag gcatgtgaac ttcttgaaga aggactggga tttgaagaaa ttatagatga
    16981 attagaaaat actcgcagta gtgtaagatt gctttttgca ccatatacac ttgatttttt
    17041 aaagcagagt ggaagagttc cagttgcaac tgctttgata ggaaatatgt taaatataaa
    17101 gcctatattt ttctttgata atggggaagc taagttggta aataaggtta gaggaataaa
    17161 gaatatagca agtaaattgg tcgatataat tttagaaatg aatgaagggt ctttagaagg
    17221 aaaaatcgtc acaataggtt gtggagataa tttacacgat tgtgaaatat taaaagatga
    17281 agtaaataaa agaataaaag caagaagagt attatttact cgaggaggag tttctatttg
    17341 ctctcataca gggccagata tattggctat aagttgttct aattagtagt aatataaggt
    17401 ttttgcatat atatgtgaag ataattttat attgttaatt tatagtattt ttgataatat
    17461 agtaaataga gtgatatacg tgttttttaa taagaggagg acaagcatta atgtttgaac
    17521 ataaaatatt taaaatggat tttgcaggaa gagaactttc tgtagaaata ggaaagattt
    17581 gtgaaatggc tagtggtagt tgtatagttc gatacagtga tagtatggta atggtaaata
    17641 caactaaatc agccaaacct agagacggaa tagacttttt tcctttaagt gtggattatg
    17701 aagaaaaatt atactctgta ggtaagatac ctggaggttt tttaaagaga gaaggcaagc
    17761 cttcagagaa agctatactt acatcaagat tgatagatag accaataaga cctttattcc
    17821 caaaaggatt tagaaatgat gttcaggtag ttgcaacagt tctatcagta gaccaagatt
    17881 gtacaccaga tatagtagca atgataggtt cttcaatagc cctttctata tcagatatac
    17941 catttaatgg accaacaggt tcagtatgtg ttggccttgt agatggtgca tttgttgtaa
    18001 atccaaacgc agagcaaaga gaaaaaagtt caatgcatct agttgtttca ggtacaaagg
    18061 aagcaataat gatggttgaa gccggagctg atgaagttcc agacgaggta atgcttgatg
    18121 ctattttatt tgctcaccaa gaaataaaaa aaatagttga gtttatagaa ggtatagttg
    18181 cagaagttgg aaaagaaaaa atgcctgttg aattatacca tgcaggagaa gaaataactc
    18241 aattggttcg cgaatttgca actgataaga tgaaaaaagc agttcagact tttgaaaagt
    18301 tagagagaat ggaaaatatg gatagagtta aagaagaaac tttagctcac tttgaagaaa
    18361 ctttagaaga ttttgaagat tttgttggag atatagaaga agtattacaa gatataataa
    18421 aagaagaagt aagaaaactt atagtacatg aaaatgtaag accagataat agaaaacttg
    18481 aagaaataag acctatatgg tgtgaaactg gcatgatacc tagagctcat ggttcagcca
    18541 tatttactag aggacaaact caagtactta atgttgctac tttaggtgct ttaggagatg
    18601 ttcaaaaact agatgggtta gatgaagaag aaaacaagag atatatgcat cattataatt
    18661 tccctgcata tagtgttgga gaagctagac catcaagagg accaggaaga agagaaatag
    18721 gacatggtgc tttagcagaa agagctttat taccagtaat accatctcaa gaagaatttc
    18781 cttatgctat cagattagtt tctgaagtat taagttcaaa tggttctaca tctcaagcaa
    18841 gtgtatgtgg ctcaacatta tctttacttg atgcaggtgt acctataaaa gatatggttg
    18901 caggtatagc aatgggactt ataaagcatg atggtaaggt tgcagtgctt tcagatatac
    18961 aaggtatgga agaccattta ggcgatatgg actttaaagt agctggaaca gagtatggta
    19021 taacagcaat acaaatggat ataaaaattg atggtataga taaagaaatt ctacaacgtg
    19081 ctttaaaaca agctaaagag ggtagaatcc atatactagg agagatgaga aaaactatat
    19141 ctcagccaaa accagaactt tcaccatatg cacctaagat tgttaaaatg caaataaatc
    19201 ctgacaagat aaaagatgta ataggacctg gtggaaagat aataactaag ataatagacg
    19261 aaactggagt taagatagat attgaacaaa ctggggaagt atttatatca ggtattgaga
    19321 ttgatatgat taagaaagct caagaactta taaataatat agtagttgaa ccagaagtag
    19381 gaaaaactta taaaggtaag gtaagtagaa taatgaactt tggagcattt gttgagatac
    19441 ttccaggaaa agaaggatta cttcatatat ctcatatagc tcatgaaaga gttgccaaag
    19501 ttgaagatgt attgaatata ggggatgaag ttgaagttaa agttacagag attgatgaaa
    19561 aaggaagagt taatttatca agaaaagttc ttttaccaaa accagaacat aaaaataaat
    19621 aacttattat ataattaaaa gcaaagtctt aggattttgc ttttttaaat acaaaaaagt
    19681 agataatttt aaaatgatag ttatggatgg cttatagttc tttttctgtc aggctttact
    19741 cttataaaga agctatttaa aagctgatta atagagagct ttattgatat atatagaatc
    19801 acttaagtta tatttagtgc ataaacagag cttattttta atagtattaa ataagaaaca
    19861 atttgtacat aattaggggg agttttaatg ataatgatgg tacttaataa gagtaagctc
    19921 aaaaaaatca taatactaat tttagtagtg ttattagtat tatcaggagg ggtaatggta
    19981 ttaaagttat ttaacaacaa gccagtattt aatttattta atggtgtgga tttaccatat
    20041 gaaagaggta caaaggataa aagtggatat gttgcattaa cctgtaatat agaccttgga
    20101 tgggaaacag agtacgtaga atccatttta gaaacactta aaaaagaaaa tgtaaagatt
    20161 acatttaatg taactggaaa atgggcagaa aagaataagg atgaattatt aaagataaaa
    20221 aaacaaggac atgaaatagg taatcatgga tacaaacatt tagattattc tacattatca
    20281 tatgaagaca attatgagca aatagagacc tctaaaaaga taattgaaga aattataggt
    20341 gaaaaaacta aattttttca agcaccagca ggttcttttg gtccagaaac agtaaaggct
    20401 gctaaagcat tagggtatac ttctatcaaa tgggatgccg atactataga ttggaaatac
    20461 aaagaccaac cagaggtaat cattgataga atgaagaaaa aagacattaa agatagtagt
    20521 ataattttaa tgcatccaac caatgcaacg acaaaatgta tagatgatat tatagctatt
    20581 gtaagagaaa aaggactaaa accaggaaaa cttagtgatg tatttaagta gacaaagtat
    20641 aaatatttgg ttaagattgt ataagttgta gttgaattaa ttaaaagact gacttataat
    20701 gtaatacata taaaaaataa atataattaa aacatagtgt tttcaataat ccaatatgaa
    20761 acaaagaata aattgttagg agaatgtaat gtataagaca aaaatactgg aaaatgggct
    20821 tacaataatt ggtgaagaaa taccatatct aaagtcaata acattaggta tttggataaa
    20881 tgcaggctct aggatagaag aagcacaggt gagtggaact tctcatttta tagagcatat
    20941 gatgtttaaa ggaaccaaaa acagaacatc aaaagagatt gctagttcaa tagataattt
    21001 gggtggtcaa ataaatgcat ttacaagtaa agaatgtaca tgttattatg taaaactaat
    21061 agatgagcat atagatacag gaattgatgt attgagtgat atgatactaa attctaaatt
    21121 tgataaaaat gatatagata aggaaagact tataatattg gaagaactta agatgtatga
    21181 agactctcca gatgacttat cttatgattt attagtggaa aatatatatg ctaatgatgg
    21241 attaggaatg aatataattg ggacaaaaga atctctgtac aatataacta gagaatccat
    21301 gttagaatac ttaaataagt attatattcc aaataacgct gttatttcta tagctggaaa
    21361 ctttaacttt gatgatatgg tggagaaaat caaatcaaaa tttggacact gggaaaagaa
    21421 aaatttaagt atagacataa gtgaggctaa gtttaatcct tgctttatat caaaaaataa
    21481 agatactgaa caggtgaact tagctatgtg cctaaaaggt attccttttg aaaatgatga
    21541 agaagtctat tcaatggcag tggtaaataa tattttcggt ggaagtataa gctcaaggct
    21601 ttttcagaaa ataagggaag aaaaaggttt agtatattca atatactcat cacagacatt
    21661 atataggaaa tgtggtgaat taggtatatt tgcaagcatg agtacagaaa atttacaaga
    21721 tgtatataat ttaataaaga aagaaattga aaatataaga gaaaactatc ttacagaaaa
    21781 agaaatatct gaaagcaagg aacagttaaa aggaaattat atattggatt tagaaagtac
    21841 tagcagtaga atgatgtcta ctggtaaatc tatgttactt agtaaaaaag taaaaactac
    21901 agatgaaata cttgaatgta taaataatgt taatattaat tcaataaaga aggttgttga
    21961 taaggtattc aatatcgaaa atattggtac atgtatagtt ggaagagatg tagaaaagat
    22021 tctacacttg gattaatatt gaaaaaagta aatctctgga ggtataaaat atgaatttat
    22081 ctgaaatagc aggtaaggaa atagttaact tggtcacagg agaaagattg ggggtcattg
    22141 gagaatgtga ccttatacta gatgaaacta caggcggtat attagcgctt ctaattccaa
    22201 aagaaaaagg attttttgcc agaagaaaag ataagtcatt tttagaagta ccatggagaa
    22261 atgtaaaaaa aataggtaat gacatgataa ttatagaata tgagggatat atttaggagg
    22321 aaaaaatgag tattttagtg caaaagtttg gtgggacatc agtagaatca tatgaaaaaa
    22381 tgaatgaagt atgtaagata gtaaaagcat acaaaaaaaa tgatgaagaa ttacaattag
    22441 tattagtagt ttcagcaatg ggaagaaaag gagctccata tgctacagat acacttataa
    22501 atttgtgtag tgcagtaaat gatgagccaa gtaaaagaga acttgattta ataatgtctt
    22561 gtggagaaat aatatcagga acaattcttg ctaatttatt gaatgcacag gggatagatt
    22621 ctgttttctt tactggtcag caagcaggta taattacaag tgatgaatat tctaatgcaa
    22681 agataaagta tataaatcct aaaaaggtaa aaagagcttt agatgatggt aaggttgtag
    22741 ttatagctgg gttccagggt gtaacagatg atggagaaat aactactctt ggaagaggcg
    22801 gaagcgatac atcagcagtt gctattggta aagctttaga atgtgaaaca gttgaaattt
    22861 acactgatgt ggatggtata atgactgcag accctagagt agaaccaaac gctaaagtat
    22921 tgagttttat agattatgag gaagtattcc aaatggctga caaaggtgca aaagtaatac
    22981 atccaagagc agtacagttg gctaaaagtg gaaatataac tttagccata aagaatacaa
    23041 tgaatccaac ttttgaaggt acaaaaatag gttctttatg tagacactta gaagacaata
    23101 tagaatatga acaagaaaga gattttaagg ttgctgttgc aaataaagat agcgtagcac
    23161 aagttaagat taagtcagca gaagaagtgt ttacagaagt attaaatgag atagaaaaga
    23221 aacttataac tatagatatg ataaatttct ttatatcaga aaaagcattt gttgtagaag
    23281 atgctgatat aaaatcatta aaggaaatac tagataaatt tgaattagat tatgaagtaa
    23341 atagagactg tgctaaggta acattgatat gttcaagaat tgctgatgaa atgtctggta
    23401 tcatgtcaaa ggtagttaga ggattatcaa aagcaggggt atctctttta caaacatcag
    23461 actcaaatat gactatatct tgtttagtta gtgaagaaga tatgcataca gcagtacatg
    23521 ctatacacca acaattttat ttaaaataaa ctgtataata caattatttt ttaatcaaat
    23581 ttaagaattt catatatatc ttaatatatt tgatttattt ggtaaaacta aattaaatat
    23641 aattttgata ggagtttttt tatgaaagat tatagagaag ataatgaaag atttgataaa
    23701 gataattgta gtgaagaatc tagttgcgaa gagagagaat gtataaagca atttggtacc
    23761 aatgaaatgc cacctcaacc tcctaaagat attcaatgta taactataat tggagaaatt
    23821 gagggacatt ttataggaaa tcctcaaaaa aaagctacaa agtacgagca tataattcca
    23881 atgctatact caattgagga aagtaatgat gttaaaggag tgttagttgt tttaaacact
    23941 gttggaggag atattgaagc aggtttagct attgcagaac ttttaaacag tacatctaaa
    24001 aaagtagtta ctcttgttct aggaggaagt catagtatag gtgttcctct tgctacagca
    24061 ggagattact catttatagc accaacagca accatgatta tacatccagt gcgaactact
    24121 ggtcttgtga ttgggataaa tgagactttt gagtatttta aaaagatgca agatagaata
    24181 attcaattta taataagaac atcaaatatc aaaaaagatg tacttgaaaa acttatgcat
    24241 gaaaaagatg aacttgtaag tgatgttggt agtgtattaa taggaaaaga agctgtggat
    24301 tatggtctta tagatgaagt tggaggacta aaagaagcac ttaaaaaatt aagagagctt
    24361 ataaaagaat ctgaggaaga aaaaaataat gattaaaatt tgtttaaata ataaaattta
    24421 tgatataatg atgtaataaa gtaggagtgt tagtgttaag gcattagcac tttttgctgt
    24481 gaaggggtaa aacttgctaa aaataaggag tgatattaat ggccacgaaa aagaagaaaa
    24541 aaaagaaggt aaatacctta agttttaatg cagaatatca taatttaata acaatattta
    24601 taggtgtatt tttattatat agtttaaatt ctaattctat gggatggata cctgtgttaa
    24661 tgcaaaatct ttttaaggga ctatttggag ggctttcaat agcaatacca tttatagtaa
    24721 ttataacagg acttttagga ttttttgatg gaaatgaata tatatatagg ctaagaaaga
    24781 ctaaactata ctacataatt attttattta tatttgtatt ttatggatta ttaaatgcag
    24841 gaactcttcc tgtagatagc ccactaaaag gtaacatgtt tgatgatgtt atgaaattgg
    24901 gtgtaagtgg acaaggtagt ggtttgatag caacaactat tgcgtattat atgagtaaaa
    24961 tatttggtat agcaggtgga tggttaataa gtatcttcgc acttatactt tctgtaatgt
    25021 ttatatttaa tatttctata aaagatttgg tgtcaaatgc aaaatcaaaa tctaaagcat
    25081 ctaaagacag caatttaacg tttaaagata aaattgcaaa tatgaaaaaa tctgcaatag
    25141 atatgatgac tgatgaagta gatgatacta ctataaataa aaaaccaggt ttctttaaag
    25201 ggttaatgtc aaaaggtctt aataatgatg atgaagaaga tgaatatttt gaagaagaaa
    25261 atagtgatgg tgtagatgat aaaactataa aaatagttgg atttaataag gcagaagatg
    25321 agtatttaga aatattagaa ggaactcaaa gtatgccaga gttagatgtt ttaaaagaat
    25381 tacaaaaagc taccaatgaa aatccagttg tagatactaa accagaaaaa aaagttgata
    25441 tagctaaacc taatttaaat atagaaaaaa ctcaacctat gagtattgta gcagagccag
    25501 ttaatgagga ttattcaaac tataaaaagc ctagcattga gcttttaaat aaagtaaata
    25561 agaagtctga tgaaaatggt aaaaagaaag tgttgaaaaa tgcttctctt ttagaaaaga
    25621 cactatcaga ttttggagtg gaagcaaaaa ttaatcaagt tacagttgga cctactataa
    25681 caagatatga aatacaacca agtccaggag tcaaggtaag taaaattgta aatttaactg
    25741 atgatatagc tttaagttta gcagctaaaa gtataagaat tgaagcccca attcctggta
    25801 aaagtgcaat tggaatagaa gttccaaatg aagaagctca aatggttggt gtgagagaag
    25861 ttctagaaag tgaagaattt aataatttta actctcctct tgcaatggga cttggaaaag
    25921 acgtagcagg aaaaattata attggagata taggtaagat gccacactta ctaatagctg
    25981 gttctacagg ttcaggaaag agtgtgtgtg taaatacatt aataagtagt attttatata
    26041 aggcaaatcc tgatgaagta aaattactat taatagaccc aaaagtagtt gaacttgcaa
    26101 attataatgg aataccacat ctattgatac cagtagttac tgaccctaaa aaagctgcaa
    26161 atgctttaaa ttgggcagtt acagagatga atagaaggta caaattattt gcagatgctc
    26221 aagtaaaaga tgtaacaagt tataatgaga aagcggaaga aaaacttcct aaaatagtaa
    26281 taataataga tgagttagca gatttaatga tggcaagtgc aaatgatgta gaagattata
    26341 tttgtagatt agctcaaatg gcaagagctg ctggaatgca cttgattgta gcaactcaaa
    26401 gaccatctgt tgacgttata acaggggtaa taaaggctaa tataccatct agaatagcat
    26461 ttgcagtatc atctcaaact gattcaagaa caatccttga tatgggtggt gcagagaagc
    26521 ttctaggtaa aggtgatatg ttattctatc cacttggtgc agcaaaacca gttagacttc
    26581 aaggggcatt catatcagag agtgagtcgg aaaaagtaat cgattttgta aaaagtcaag
    26641 ttaaagatgg aataaaatat gaagaagata taattgaaac tatatctaag gttaatactt
    26701 caaagggtag tgatgaggat gagtttttga gtgaagcgat agaatttgtc gtggaaagtg
    26761 gtcaagcatc tgcctctatg ctacagagaa gatttaaaat aggattcaat agagcagcta
    26821 gacttataga ttctatggaa gaaagaggaa taattggagc aagtgaggga agtaaaccga
    26881 gaaaggtatt aataagcaaa caggatttgc agaatttaga aggtgaatag aattgtcagt
    26941 tataaaaata gaaaaagcac ttaagctaga taaagtaata tttgtagatg tgagaactga
    27001 aggagaatat gaagaagacc atatattgaa tgcaatcaat atgcctcttt ttaaaaataa
    27061 tgaacataat gacgttggaa caatttataa gatgcaggga aaacatgaag caatacaaaa
    27121 agggtttgac tatgtatcgt ataaattaaa ggatatatat ttacaagcag cagaacttgc
    27181 attaaattat gataatattg tcatatattg tgcaagaggc ggaatgagaa gtggcagtat
    27241 agtaaattta ttatcatcat taggtgtaaa tgtatatcaa cttgaaggtg gatataaggc
    27301 ttatagaaat tttgtattag agtatctaag gcatgtaatg gatacaaaaa actttgtatc
    27361 tgttcatgga ttgactggta caggaaagac tgatttgtta catttattag atgaaaaagg
    27421 aatagatgta ctggatttag aaggcatagc taaaaacagt ggttctacct ttggttttat
    27481 aacttttgat aaaaagccac cttctcaaaa gaactttgaa acaaaactat ttgaaagtat
    27541 atttttttcg aaagagaatt atatatttgt cgagagtgaa agcaaacgag ttggaagtgt
    27601 tacagttcca aatgaaattt tcgaggcaat gacacgagaa ggacatcata tattattaga
    27661 atgtgatatt gaaaatagag ttgatagact ttgtagagat tatatttatg ataaagatga
    27721 aggtaatata ttgattttaa aagaatgtat aaacaagttt agaaaaagat tgggtaataa
    27781 agtagtagat gattatattg atttattaga atcaggtgaa tataaagaac ttgtaaaaag
    27841 atatctttta gaatactacg acccacttta tatgcattca gtagaaaaat ataagtatag
    27901 taagattata aattttaatg atacacaaaa agctttagaa gatgttatag acttatatga
    27961 gagtatattg gaaggagaaa gtgaatgtta aaaatagcat tagaatcatt aggatgctca
    28021 aaaaatttag tagatgcaga aataatgatg ggaattttaa ataacaaagg ctataaatta
    28081 attggagatt ttgaagaagc tgatgtaatt atagtaaata catgtggatt tatagagtca
    28141 gctaaacaag aatctataga tacgataata aactttgcag agttaaaaaa aactggcaat
    28201 ttaaagttgt tgatagtaac agggtgtcta gcccaaagat attctgaaga attaaaaact
    28261 gaaattcctg aaatagatgc tatagtagga acaggaagct atcaaaatat agataaaata
    28321 cttaaagaat taagtgaaat gcataaaatt gtaagcctta atgatataga gtttgtattt
    28381 aatgaagatt taccaagata tatatctaca cctagctata tggcctattt aaaaattgga
    28441 gaaggatgtt ccaataattg tacttattgt ataataccaa aactaagagg taaatataga
    28501 agtagaaaat ttgaagatat aattaaagaa gctaagaaat tagctgaatc tggagtaaaa
    28561 gaacttgtgg ttatagcaca ggatacgaca aagtacggtt ttgatttata tggaaaagaa
    28621 agattatcag aacttttaga agaacttgca aaaatagatg gatttaagtg gataagggtt
    28681 atgtattcat atccagaatc tataacagaa gaattgatac aagttataaa gaaatatgat
    28741 aatatatgta gttactttga tatgccaata cagcatgcaa gtaacaatat tttaaaatta
    28801 atgaatagaa aaactactaa agaagatata ttaaataaaa tcaatctgat aagaagtaat
    28861 ataccagatg ctatacttag aactacaata atagtagggt ttcctggtga aacagaagat
    28921 gacttcaaac aacttgtgga ctttgttgaa gaggttaaat ttgatagact tggtgcattt
    28981 gcatattcaa gagaagaaga tacaccagca gatagattgc caaaccatat agatgaagaa
    29041 gtaaaaatac aaagaagaga tactttaatg atgattcaac aaaaaatatc tgaagaactt
    29101 aatgacaaaa agataggaaa aacttatgag gtgttaatag aagaacagat agaagataat
    29161 gtatatacag gaagaacaca aggtgatgca gaagaaattg acagtatagt gtatgtaaaa
    29221 agtgtagaca atcttgaagt aggagaattt gtaagtgttc aaataaatga tgcaatggaa
    29281 tacgatttaa tgggagatgt tttatatgaa cttgcctaac aagttaactt tgtttagaat
    29341 atttttaata ccagtatttg ttttaattat gttgctcaat ataccaaata aatttttaat
    29401 agcttgtatt atttttataa tagcttcaat tactgatgct ttagatggaa aaatagctag
    29461 aaaatacaat ctagtcactg actttggaaa atttatggac ccattagcag ataagttatt
    29521 ggttatttca gcacttacat gtatgataga agaccatctt gtaagtagtt ggatggtaat
    29581 tataatagtg gctagagagc ttacagttag catattaaga gctatagctg ctgctgatgg
    29641 aaaagtaatt gctgctggaa acagtggaaa acttaaaacg ataactcaaa tggtatctat
    29701 agtgttttta ttgttaggtg ctcagtttga aaatgtattg atattaaata ttggtgaaat
    29761 tctcattctt atagctacac tacttacatt atattctgga tgggaatatc tatataaaaa
    29821 taaagagctt tttatgtctt ctaagtaaaa aattatgctt taataaataa aaactaatga
    29881 ttaataaata aaaaataaca acttaaaatt ttaaaaatgt aaaaaaggg
//
LOCUS       DAMKNB010000042        29486 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.044, whole genome shotgun sequence.
ACCESSION   DAMKNB010000042 DAMKNB010000000
VERSION     DAMKNB010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 29486)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29486)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29486
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.044"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            complement(69..281)
                     /locus_tag="PC494_002135"
     CDS             complement(69..281)
                     /locus_tag="PC494_002135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF3912635.1"
                     /translation="MAILMKTKIKEYREKLLMTQNELAKLVGVRRETIVHLENGKYNP
                     SLKLAMDIAKVFDTTVENLFEFIEEE"
     gene            complement(282..698)
                     /locus_tag="PC494_002136"
     CDS             complement(282..698)
                     /locus_tag="PC494_002136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3912636.1"
                     /translation="MSKSETGVRSKLILELLVITYFFIAVLATKYIFKGPSTASLPGL
                     SWLIVFGCYSIYNKKYNDLVDESSEFILSKVNKIAIKIMIYSIVIISIFFATPYTSNI
                     NISNLDTGIILIAVLFIQSLSKLVLYIYFDKRGICN"
     gene            complement(766..1179)
                     /locus_tag="PC494_002137"
     CDS             complement(766..1179)
                     /locus_tag="PC494_002137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3912637.1"
                     /translation="MSKSELGVKTNLVSELLMISYFFIDSLLKKFIFKEGNLCITFII
                     LFAFWACDFMYNKKYNDLVDEASKLMLLKVDHIASKIMLYSILLIAVFFSANYTRGLD
                     ISNLDIGVILLAILFIQSLSKLILYIHFDRKGICN"
     gene            complement(2012..2641)
                     /locus_tag="PC494_002138"
     CDS             complement(2012..2641)
                     /locus_tag="PC494_002138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine amidotransferase"
                     /protein_id="HDF3912638.1"
                     /translation="MKNRKVYMYVFDTMSDWEVAYLTAELNTGRYFKKGLKPLKVITV
                     GIDKNPIITMGGLKVLPEITVDEFNMESKDLLILPGGNTWLSMNHEIILEKVKEALRQ
                     DSIVAAICGATLGLAKKGLLDFRNHTSNDLEFLKMVIPNYSGEKYYKTESVVSDENLV
                     TASGIAPLEFTFQVLKLLDVFESEALNSWLNLYKTHDSKYFFELMNCNK"
     gene            complement(2720..3682)
                     /locus_tag="PC494_002139"
     CDS             complement(2720..3682)
                     /locus_tag="PC494_002139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017561613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WYL domain-containing protein"
                     /protein_id="HDF3912639.1"
                     /translation="MAKIDNMMSILWMLNSDKKITAKQIAEKLEINIRTVYRYIDVLS
                     ASGVPIISDTGHNGGYSLLNNFTKAPLFFDIEEQKSLLHAALFAKKEGYFLDEALDKS
                     ILKLKMYSNQKQEDILTNHLRALEVIKPIGKVSIESVLKKLENSILKELSVEINYHAG
                     RKVKSKYRIINPYGIVHWNNNWYVVAFCNMRNEVRSFRVDRISEIIETSNTFNRPTEF
                     SASEFFIKGIIPEIKDEQNIIQLVIEGSIDSLDSLSQHWFLGHYLKERTPNKIIFMLE
                     EEVICKYIPNILLPYRKTIQVIEPLSLRKKIIEDLLELIDYYQI"
     gene            complement(4444..8040)
                     /gene="cbpA"
                     /locus_tag="PC494_002140"
     CDS             complement(4444..8040)
                     /gene="cbpA"
                     /locus_tag="PC494_002140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding adhesin CbpA"
                     /protein_id="HDF3912640.1"
                     /translation="MQQKCKKKALSMILSISMGLGSVASFNASNTFADTIEESTNAGN
                     AEGDTNAGNAGGDANAGNAEGDANAGNAGGDTNVGNPEGDANAGNAGGDANAGNAEED
                     ANAGNAEEDANAGNAEGDANAGNAEEDSNAGNAEEDSNAGNAEGDMNALVVEEATAED
                     PTSVGDFKISGGEINVDFKFASGVLTILSGKQMTIQNNNPNTPTTHRIVIPKDVKAEL
                     IFDGVNIKTASNSPFTLTPDKDGGAYAHVILQDGSENKLESGDVYYPGMRAGKGTTLI
                     IDDSVVNRDIEGEFIVSEGGKIPRDVTLENGDKLKKGDRLTLLDSNNRGSLKVVGNYY
                     SAGIGGGNTESGGNIIINGGAITAIGQESSRNTGYGAGIGGGGNGSGGDITINGGTIT
                     AKGAYHGAGIGGGYYTTTKNALSPSVVDPSTGSGYSGNITINGGLSYSYGGAHGSAFG
                     DGCVNPGTNRGYRILVTGGTILPYMTGVGDWIFDLSATTGDVIVTGGSLKATTFKSLG
                     GAVAYGDLEKKTKVFMNKISLTYLGQDKVSTTLVDDFKMLIDGKIYPYGAPSYTDAQG
                     ILYLWFSDKFTGSEVSVNLVVIDKITGEVLKPDDFYIKDIGSGSQFLKQYEEFTIDDT
                     PPYLIIKRYDGLPFEEDVEKSFLDWLLKDGGIPITTPKGEKLTDKKFMTISSQRLNEE
                     TMEPDINLGSDDLTKQVDAGKYQLSITSTQFSSIYPFKDAYWGHRAYYKAEIIPADTE
                     TSLVVEESKAKTDVFKPTDTFTLNVTISPDKKEGPDCASPRGYVQFYINGKEYKDPVE
                     LKTHNKGSESHNYSTASIEWRPLDSNHHIFTTEQTITVKYIGDDINYIEGSEDEKKLK
                     LDMTNVDVDGDGIPDINIDTDGDGRPDINIDTSGDWKPDINIDTDNTGEWKPSTEGGN
                     GDGIWKPDKNIDTNGDGNPDTDYNRPAIDTDNDGVDDYWKPDKNVDTGSGGYDTGNPN
                     LNKPDPDNGGNSKPDSGNGGNSKPDSGNGGNSKPDSGNGGNSKPDSGNGGNSKPDPDN
                     GGNSKPDPDNGGNGKPDPDNGGNSKPDPDNGGNSKPDPDNGGNSKPDIDTDGDGKPNI
                     NIDTDGDGKPDINIDTDGDGKPDINIDTDGDGKPDINIDIDGDGKPDINIDTDGNGKP
                     DINIDTDESLDSNVGQNVQTGDQSNIMLDLALMFISLFFLIKNLTNKYLRRK"
     gene            8309..8881
                     /locus_tag="PC494_002141"
     CDS             8309..8881
                     /locus_tag="PC494_002141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class B sortase"
                     /protein_id="HDF3912641.1"
                     /translation="MKKLVKILINIICIITLIFSSLSIYIKLSEYKKADEVYTELREN
                     TINNSKYQELYDKNNDYRFWLKINNVNIDYPVVQGYNNDFYLTHDFYKNYLPLGSIFM
                     DYRNNFENDKSLIVYGHYMKNKTMFGQLENYTDEVFFKENNLVEINYKVQTYTYEIFS
                     VYTADLINRDYLSIHFNNNDEFKYSLNYIT"
     gene            complement(9894..10556)
                     /locus_tag="PC494_002142"
     CDS             complement(9894..10556)
                     /locus_tag="PC494_002142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF3912642.1"
                     /translation="MKMLKVIDIKKIYGKGENEIKAVDGITLEIEPHKFSAIIGQSGS
                     GKSTLLHCMAGLDKPTLGNVFMDNLDLYTLSDEKLSNLRSKEFGFIFQNYNLIPVINV
                     YDNIVLPILIAKGKIDNNYINDLITKLGLESQINKFPNELSGGQQQRVAIARSLANKP
                     SIIFADEPTGNLDSKTTNEVMNLLKYCVNEYKQTLVMITHNDEIAKMADCIITISDGK
                     VI"
     gene            complement(10573..13128)
                     /locus_tag="PC494_002143"
     CDS             complement(10573..13128)
                     /locus_tag="PC494_002143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HDF3912643.1"
                     /translation="MGIYLKMSLAYLKKNKLRTLLLIIGVMLGVMLIFGPSVIKDSQN
                     ENNVVAIHELYSGYHVEFSDLTLDDAKKLETDEKVSKGNSVQNLGRISDKKGNSFILT
                     SSNEEYLKSRYNKIIEGRLPKNNNEIVLEKKALEAMNLSEGVGSTLNLTIKKNYKDTN
                     GSNRLFSINKEFKIVGVMEKPKGYYDVVWQYEAVTYGNDETNNIIPHDAISYNSILSF
                     KSGWRNIEGECDYLMKKYKLGQKSFLPNVPLVRELRYVEDDKNDPNVFKRNVLITTVS
                     IIFIFNIFNITLNQSVKEMGLFRLMGAKKRNVRCMIIYQALIITIIGILLGLVAGVTY
                     SYIGISNYNEVLYSEAGLNPKLYINNEIVIKAILVGIISVFISCIIPTFKIGKISPIE
                     SIINTDKIKNHRSRLGIDRLVSKIFGFYGFMGLKNIGRNKVRAAISMLSIALGGYIFI
                     TTFSSMQEEVNSKIEDMQNRYNITMQFGVNADPQISKYTDSDVENIEKIKGVKSIHKI
                     QITNGMFTFNNKDINKEFTTYNGVEKKEIMEDKLVLKLYDDDYIDEKLNDFVEEGSLD
                     DIKKDTDGYPNVAVYNYFYDIVDDHTIKPIFKELNIGDIITVKIPVEENNTIVYKEMK
                     VRVAVILKDEWIAMGDGDFMPDLEIITSNIHSKNITGEQKYTQLGINLENPYDEIVNN
                     EIQKISRSIPGSLFNSRLSYHEMSESIYKSYIKSQIAIIALVLIIASINIFCTIRTNL
                     LIRKKEISTLRALGVSLKNMKKMLIYEALAYAVFSFIIAMIPSFINLVKFTNWNNDAY
                     INYGIENFMSFTFPIKESLLFFAISVFVCLIAVVVSNRDFESMNIIEGIKENE"
     gene            complement(13361..13555)
                     /locus_tag="PC494_002144"
     CDS             complement(13361..13555)
                     /locus_tag="PC494_002144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3139 domain-containing protein"
                     /protein_id="HDF3912644.1"
                     /translation="MRKYKAILLTLIISIIAIIGFIIYNNYFRKWNEAEKYIDKYMTY
                     QGVSGDDIERITKEKYTKEN"
     gene            complement(13567..13746)
                     /locus_tag="PC494_002145"
     CDS             complement(13567..13746)
                     /locus_tag="PC494_002145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3912645.1"
                     /translation="MIHVEISEKEFFRKIEEVFDKGEGNIEVDNLGDIKIQVKKFDDK
                     TKSLELKLIKEFKLK"
     gene            complement(13751..14008)
                     /locus_tag="PC494_002146"
     CDS             complement(13751..14008)
                     /locus_tag="PC494_002146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3912646.1"
                     /translation="MSKKISESIENSGLRVAENKSDGSFVLSLGNLEYTKEQPSQVLH
                     YSMTKDKKGTKEILSIQCVKDFSYNEKLSEDDKFIMAIYNI"
     gene            complement(14268..15661)
                     /locus_tag="PC494_002147"
                     /pseudo
     CDS             complement(14268..15661)
                     /locus_tag="PC494_002147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428529.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
     gene            complement(15655..15900)
                     /locus_tag="PC494_002148"
     CDS             complement(15655..15900)
                     /locus_tag="PC494_002148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LytTR family transcriptional regulator
                     DNA-binding domain-containing protein"
                     /protein_id="HDF3912647.1"
                     /translation="MLIHTKNKTFDAICILEKIEKDLNIEELVRCHKSYIINLNYVEN
                     IKSNTAILDSQEEVPISRYRYKDIKERFLKFIGDRIC"
     gene            complement(16217..16369)
                     /locus_tag="PC494_002149"
     CDS             complement(16217..16369)
                     /locus_tag="PC494_002149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3912648.1"
                     /translation="MKNLNKNTILGEVIITIAACDDEKEIQIVIKNQVDNILKNKNKE
                     YRIKKI"
     gene            16978..18444
                     /gene="dndC"
                     /locus_tag="PC494_002150"
     CDS             16978..18444
                     /gene="dndC"
                     /locus_tag="PC494_002150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA phosphorothioation system sulfurtransferase
                     DndC"
                     /protein_id="HDF3912649.1"
                     /translation="MAVNYLDNNNLENLYDEMQAVYLNDDRPWIIGYSSGKDSSCVVE
                     LTFRMLKRLPKEKRHKEIYVISSDTLIENPIILDYLKNNIDKINESATEHDLPISAQI
                     VYPELNDSFWANIIGRGYPTPKSIKYRWCTERLKIKPSNKFIKEKLEQKDVIVLLGVR
                     KEESSARKSRIEKREIEGYLLTPHETLRGKNKLAYVYTPIVNFSTADVWDVLYHQNDN
                     FIDFGGEFGPSPSTSWGTDAMELFQMYMKGSGDSDECPFIADEASAKSSCGNSRFGCW
                     ICTVVKEDKSLNGFIESGHDELKPLLEFRSWLISERDKPKNRKKHKRNGSVIKKDGRI
                     MFGPFTFEARQTILRKLLETQLEMQKFYPDLQLIQLGELKAIDDIWDNEEDLTGNILS
                     KIYKEVVGKNLPWSEYKKPVFDDLTLNIISEKCSEYDINIDLFNKLMIDTNKYKYFSN
                     NTKLKTSIERILNQQWLHQDIIEKIEEESNKELKYENK"
     gene            18431..20590
                     /locus_tag="PC494_002151"
     CDS             18431..20590
                     /locus_tag="PC494_002151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HDF3912650.1"
                     /translation="MKINKLVLKNFRSYEEETTFNLNTTSEKNIILIGGKNGAGKSTI
                     FEAIKLCIYGPIAYKYQGFNSSYISRVKSNINNNSLRNSKVDTLVSVDIEISEGTEKN
                     TYTLIRQWTFKDKKLNETFSVYKNFSFTPLNADELNYFENYITSIISPKIFDFFFFDG
                     EHLYDFFIGKNSNIHLKESLLSLCNFDTFDILKKMLISTNRSNKNVSDEINIIKDDYL
                     NLEVEINNLNSQEKNLSYELEKISSEIEKLQQEQLKIKKEFRKKGGILAEEREMLNSR
                     IAELEGNRFIINQNIKDFCNDILPFLIVKKQILNLEKQLKVENDSILYSHLKDKLNIE
                     YIKNLLSDKIMSSSLDEIALTVSEALIEDIKPDSYEDNFESIHKLSNDESSKLLSLIN
                     TILNFDNNSIINSFGEHRSISNELADIRHKLNTSFKDETLNTYINDISSLSDKIDSLL
                     KSKNLLVTSLDKLRLEIAETITKRDKSKAKYIYLLQHNNIVDISSNLILMLDEIITTL
                     TETKIKLVQDNFMYIFKRIIQKDNFISSIDIDANFNISLYINKIYNSLELENLVENIG
                     SEEMEKKLGKLFFEDLFNLYRVKDKDDLFNAIKNNTQSTFLNLRTKVDIDEFSSGEKQ
                     IYILCLYWALLKSSEIEIPFIIDTPYARIDDTHRNNITSEYFSTISDQAIILSTNTEI
                     DEKSYKIIKPKLSNEYLIEYDNKNKKTIQNKGYFFEV"
     gene            20593..20976
                     /locus_tag="PC494_002152"
     CDS             20593..20976
                     /locus_tag="PC494_002152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DndE family protein"
                     /protein_id="HDF3912651.1"
                     /translation="MGFRLKTSIQTKEIFEELGSRMNLKPFALCKLAISISLSNSEPI
                     ENYESIDNNGLELNRQTITNQYDTLFKTLLEQHAGRHLSDDEYFPNQVKLHIDRGALM
                     LKNRYNYSSNLEHFITQIVQENNNL"
     gene            complement(21086..22228)
                     /locus_tag="PC494_002153"
     CDS             complement(21086..22228)
                     /locus_tag="PC494_002153"
                     /inference="COORDINATES: protein motif:HMM:NF014044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HDF3912652.1"
                     /translation="MKIIFGNIKNNNKELIWDPTNSIKVPHPNTGIIGTMGTGKTQFT
                     KSLVTQIHREQKHNINGKPIGILIFDYKGDYIKDDFVDATSAKVYEIYHLPYNPLTLI
                     IPERIKPLLPVHTANSLKETIAKAFGLGPKQEVILRELIMKAYEKKGIKKDDENTWVK
                     SCPTMQDVLSIYLDDREIKKDDKLYAALSSFNDFEIFEPNSEKTKNLFDLINGVTVIN
                     LSYYDSGIQNLVVAITLDLFYSQMKALGSSDITGNGEYRQLNKMILVDEADNFLSRNF
                     TSIKNILKEGREFGVGTILSTQLLSHFSTSENEYQNYISTWIIHNVSDINNKDIRYIF
                     NSKNKSEEDNIYNKIKNLAKHESLVKMPSENSPIYIRDKAFWELNK"
     gene            complement(22238..26209)
                     /gene="dptH"
                     /locus_tag="PC494_002154"
     CDS             complement(22238..26209)
                     /gene="dptH"
                     /locus_tag="PC494_002154"
                     /inference="COORDINATES: protein motif:HMM:TIGR03237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA phosphorothioation-dependent restriction
                     protein DptH"
                     /protein_id="HDF3912653.1"
                     /translation="MSDQFYRYLAKNLVKYFESREIKSGDKFNIQFEREEQVKIMYDV
                     LEKESNSRPFTYNIMNGSKYQTFSMNVSGIQLIVASNNNTTNDFLIRLRNLIGNVASD
                     EFKDSAILFIHNMTLDSLIRGTESLQKEGMPFHTKTLVKDIQNKLENDKLKEDIKHIL
                     YFVLDRMNKSILEDNSSIFQYENILDILNKGRIEKSEYSKFGLFYDDNMLDNKSSKAI
                     KERLLDNEKLFSIVNSIHQYGDPKLELEKHFDSKGIDLLKDENWKYSTYKDIKSSQER
                     MKNKKVELLCIECVENLKLWSKPDIENKSKRKNILLFNKDKLDIINLCIKFDKKIEKT
                     SFSIDKMSKTYTEVKASGNKAYISININISETTFTKVKYNDGIIKYEFRICIVSCDEN
                     ILNDIKSNYGIVINSKRSMLVTNTDDDTIVINPKGIIERKIQIDEFENEINLEEGERL
                     DLELNVELEEDVEFIKIDVVYDQSVITIVKQEEKEQPISISGMKTWKLKRERKESFKY
                     LGNSKIVQGTSEYFPKENFKENLQIEKYIIENNIMHCTILEEKYKIIELDVDSRIKEA
                     YKNLISYYKVNDCIPSLAYYDVDLVNISKNYINTILEVFEDIKNGKVLSKERLNIAKV
                     GTIHRIDKEEELFLTPLHPVNVAYQLMINNVIGDEEVKEGILKLLGSKYLMPYIYKGK
                     NSLYKVVDQRHSPEWTYYVDHDMSRYKGSRDYVSKLTKEKINEFIEHFTYLFRDISKS
                     VMKIKLINLGDCKEVLLGIFDYYIKKLGKGEEINNLISIDIYIYGDKSIINSFEEIAF
                     YNSINDIKKHFNVNLSVDNYSEEDVLNLFRDKVKFYKKDKMSDLYEYSHLTLYQMDKD
                     VNITSSSMDDIKTGVALNGLIAGVPSIYLEDTYRTGFGSKFMATTKNELLNISMKFNS
                     LTKSIGTGDPFNDNLSVTTSISENNSSFLNKIYKTSHWVTFIDPKVDLNFFKDDENSN
                     DLLIIHYSDQYTTSSGYDAITVTRKSEQYKFIIEEFLNSKDIKVEEDTIPNLINYFNA
                     INGDWLLRLISSKSQFPREKLSILSAIKISLAYFYHPNIIWIPISLEEILRVSGGAGL
                     KQAGGLFTVKKLTGDTGSYSDDLLLVGIENKNNKIKVYFYPVEVKIGDNNESVIKKAI
                     IQANKTRDLIEEYLTESENDSQKFTKLMYRNFMIQLAIVSAQKMKLYHIWDEQNWDDI
                     INSDIRTNLLNDNYEISNDLDEFIGRGAVISFKKGTYYNGNLGKEGNITILNLSEQEG
                     YNNIVMDLEEMKEKYIRGESDFVIQEMLINKYLDNTIGIQNMDKNVILDTNVMLNKTK
                     DYD"
     gene            complement(26190..27611)
                     /gene="dptG"
                     /locus_tag="PC494_002155"
     CDS             complement(26190..27611)
                     /gene="dptG"
                     /locus_tag="PC494_002155"
                     /inference="COORDINATES: protein motif:HMM:TIGR03236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA phosphorothioation-dependent restriction
                     protein DptG"
                     /protein_id="HDF3912654.1"
                     /translation="MQLIINKEYFKQNYMIDKGIARHNSVKNIVILPYTTTTKEKSKL
                     KEKVERFESCVGEFCRLVYNKKMNIKERQLKDIKLLIKDINVNSSDDSVQLESIIREL
                     FLDEEENMYIFHPKLLNYIHMPSDSYYKKLSKFLYDVLLNSTDNITIKNKINKCFEYE
                     PDNIMELIILKNLPELENEETSKSIYKCICKNVSKLFQEDLEFMLNYPELIINEFERL
                     LKYYYFFYVSQLSIKLSHFFDGDRDRTEKVYFILSWEKASKTRISYNMGWKMLESHIR
                     ILFSHVHTLEILNTNNDISKYDYVDLNKIIKNLSENERLRLYENIIDIKNTYVKSITD
                     VQWDDYDEQTKVYKNDNIKEEICDLHKRIDYQFKKSSREANYKRYKNLFEEYCKLNFL
                     KKAGPLGNVLKINQEELLFMTKLCMKNKTKIKLKELFEEYEKRGIYFDRDSQSKVVEL
                     FEKLNIIEKKSDSGDAQYVRSIL"
     gene            complement(27599..29407)
                     /gene="dptF"
                     /locus_tag="PC494_002156"
     CDS             complement(27599..29407)
                     /gene="dptF"
                     /locus_tag="PC494_002156"
                     /inference="COORDINATES: protein motif:HMM:TIGR03238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA phosphorothioation-dependent restriction
                     protein DptF"
                     /protein_id="HDF3912655.1"
                     /translation="MSNGCLIDELKKLKESSKEAVENISDFSSFKKYMHVKRQVENEL
                     LDIIKYTADSNKAELILVCGGVGDGKSHLISYLNNKYPEIMSKFIIHNDATESFEPNK
                     TSIDTLNDVLDDFSDKKMDNSDKKLVLAINLGALSNFLESEYVNKFTKLREFVENKGI
                     LDISISDDDDKNSNFHFVNFSDYHIYTLNADKPKSRYIESIINKIIAEDNQNIFINSY
                     KTNCTHCIVNYKCPIKNNYEMLMRDSVRETLVDILIESTVKYKIIISTRSLLNFIYDF
                     IVNVDLDNKNNKDLIKFVEELSYEAFIKYIFVSNLYNHSELSQILNAVNKIDPINITS
                     ENLDNIIIKLSNTKDMTILFNQYLNLSKNSYLESSMTNREIIESALNSSKNELSRKIL
                     KYNIINTFIRLHIFIPKNNLQLRDNIYISYMRNLYYFNKGEKTYLSNLYDDIKEALYS
                     WNGRIQDDRINMSIGKNQMRYKISQRLNIIPDLSKLRKCTEEELHKFKPSLEIGYKND
                     EKENQDTCTVDIDFNLYKLLMRVKYGYTPNNNDKYTYINFVVFMNKIHKLGNQNRELY
                     IEDRLEDTVPKYKLTYDKEFDKFKFIRVNGVKVCNL"
BASE COUNT         9921 a         4558 c         3065 g        11942 t
ORIGIN      
        1 tttaacaaac ttaataatta aataactata ttttattatc catcttataa atgtttataa
       61 actttccact attcttcttc aataaattca aacaaatttt ctactgtagt atcgaatact
      121 ttagcgatat ccatagctaa cttcaaagaa ggattatatt tcccattttc taagtgtaca
      181 atagtctcac gtcttacccc aaccaattta gcaagttcat tttgcgtcat aaggagtttt
      241 tctctgtatt ctttaatttt tgttttcatc aatattgcca cttagttaca tatccccctt
      301 ttatcaaagt atatatacaa cactaattta gataaagact gtataaataa aactgcaatg
      361 aggattatac ctgtatctag gtttgatata tttatattac ttgtataagg tgttgcaaag
      421 aaaatagata ttattactat agaatatatc attattttta ttgcaatctt attaaccttt
      481 gatagtataa attcagatga ttcatcaact aaatcattat attttttatt ataaattgaa
      541 taacatccaa aaactattaa ccaactcaac cctggaagag aagcagtgct tggaccttta
      601 aaaatatact tagtggctaa tacagctata aaaaaataag ttattacaag caactccagg
      661 ataagctttg atcttacacc agtttctgat ttagacatat aaaatcactc cttaaaaatt
      721 atattctcta tactctttaa ttttcgtttt tatcaatatt atcacttagt tgcatattcc
      781 ctttctatca aaatgtatat acaaaattaa tttagataaa gattgtataa ataaaatagc
      841 taagagaatt acacctatat ccaaatttga tatatccaaa cctcttgtat aatttgctga
      901 aaagaaaaca gctattagca aaatagaata taacattatt tttgatgcaa tatgatcaac
      961 ctttaataac ataagttttg acgcctcgtc aactaaatca ttatattttt tattatacat
     1021 gaagtcacat gcccaaaaag cgaataaaat tataaaagta atacaaagat ttccctcttt
     1081 aaaaataaac ttttttaata atgagtctat aaaaaaatag gatatcataa gtaactctga
     1141 aacaagattt gttttaacac caagctctga tttagacata taaaatcacc ccttaaaagt
     1201 tatatattta taacacctta tgttataaat atataacttt tccaaataaa ttgcaataga
     1261 atattgaaaa tattcaataa tatcttcata aatatatttt ataaaagatt ttataataaa
     1321 cattacaata cagtactaaa ttagtttatt tcatctatca tctcaatcat atcatttact
     1381 aactattatt ctaatgagca tataacattg aaacttataa ttatacaacc taaatgcctc
     1441 ccaatgtacc ctcaaaacat catttcctgt aactgaagta taattggtat attttatcac
     1501 tgaaataaaa aaacactagt caataaagac tagtattttc aagtatttta tcattctttt
     1561 tttaattatt ggagacgaat catcagaata atgcccataa tttatctata tgcaaattct
     1621 aaatttaaaa taaagtttca gataaattta ctattctatg ctatgataca acagaaaaaa
     1681 ctgaaatcta tgagtggtag cttcatataa tcctagttcc tacagtaatc aaaactgagg
     1741 tttattctat atgtaactaa tgataaattt tattatagga gttattagat ctatttgtgt
     1801 tactataagt agtaattata tatatgataa ttttttaaca cttttctgtt ggctatatag
     1861 aaagtggttt agaatttaaa tttaaataaa atttaaattc accaaaaaga aatctatatt
     1921 agaaaccact actctattcc accagattgt aattttttgt tctttatatc acaatgctat
     1981 accatattaa attgaaaaat aagttttaaa tttatttgtt acaattcatt aattcaaaaa
     2041 aatattttga gtcatgagtt ttgtaaagat ttagccatga atttaatgct tctgattcaa
     2101 aaacatctaa aagtttcaat acttgaaacg taaattccaa cggagcaatt cctgaagccg
     2161 taactaaatt ttcatcacta actacagatt ccgttttata atatttttct ccagagtaat
     2221 ttggtattac cattttaaga aactctaagt cattacttgt atgatttcta aaatctaata
     2281 gccctttttt agctaggcct aatgtagctc cacatatggc tgcaactata gaatcttgtc
     2341 ttaaagcttc tttaactttt tctaatatta tctcatgatt catagataac caagtatttc
     2401 cccctggcaa aattaataaa tccttacttt ccatattaaa ctcatcaact gtaatttcag
     2461 gtaaaacttt taacccaccc attgttataa taggattttt atcaattcct acagtaatta
     2521 cttttagtgg ctttaatcct tttttaaaat atcttcctgt atttaattca gcagttaaat
     2581 atgccacttc ccaatctgac atagtatcaa atacatacat atatactttt ctatttttca
     2641 tcttttttac tccttatgta attaatttat atatctaatt ataaaataac ttaactgaca
     2701 tattcagtca gttaagctat taaatttgat aataatcaat taattctagt aaatcttcaa
     2761 ttattttctt cctaaggctt agtggttcaa ttacttgtat tgtctttcta taaggtaaaa
     2821 gtatatttgg tatgtacttg catattactt cctcttcaag cataaatatt attttattag
     2881 gtgttctttc tttcaagtag tgccctaaaa accaatgttg gcttaaacta tctaaagaat
     2941 ctatactccc ttctataact aattgaatta tattttgttc atcttttatt tcaggtataa
     3001 ttccttttat aaaaaattca cttgctgaaa attctgtcgg tctgttaaat gtatttgatg
     3061 tttctatgat ttcactaatc ctatccactc tgaaactacg aacctcattt ctcatattac
     3121 aaaatgcaac tacgtaccaa ttattattcc agtgaacaat tccatatgga tttataattc
     3181 tatattttga ttttacttta cgacctgcat gatagttgat ttctacagat agctccttta
     3241 atatactatt ctccaatttt ttaagtactg attctataga cactttccca attggtttta
     3301 ttacttcaag ggctcttaag tggtttgtta aaatatcttc ttgtttttga tttgaataca
     3361 tttttaactt taatatcgat ttatctaatg cttcgtctaa gaagtatcct tcttttttag
     3421 caaatagtgc tgcatgaagt agagattttt gctcttctat atcaaaaaaa agaggtgctt
     3481 tagtaaaatt atttaaaagg ctatacccac cattatgacc tgtatctgaa attataggta
     3541 ctccactcgc agaaagtaca tcaatatatc ggtacactgt tcttatattt atttctaatt
     3601 tttcagctat ctgttttgct gtaatttttt tgtcagagtt taacatccac agtatagaca
     3661 tcatattgtc aattttagcc atgtagtttc acctctttct atttgttata taaagttatt
     3721 atataacttt ttgattgatt ttttacaaaa aaacattagt aaactgctaa taatttatac
     3781 taagatttat ttcaaatatt tatagatagt ctttttctat agttaagtta tccattaaat
     3841 tacatagtag tatatctatt ttagttgata tattttcagc tacctccctt gaatattatt
     3901 acaataagtc taaatcttct ttcttccata aatatattat gaggaaagac tatcatcttt
     3961 aatggtttaa tagtataaaa gatattaatt taaaaaaatc tatttttata tcagatgggt
     4021 attgtttttt ataaaactga aaaaatcacc taatagaatc tatgattttt taacataacc
     4081 tccataaatt agttccaatt atcacttcaa attcaaattt ttatctgaag aatatacaat
     4141 catatttcca tactcaacat aatattgagt gtttggcttg tatttacaaa ttattattct
     4201 aacaaaaaca actatacata gattaaaatc atcttctaaa cataactact aaaattgaat
     4261 taatgatatc aattccatta atctctttta ataaaaaatt ctcttttcta tatgaaaatt
     4321 atttcaaaac ttttaagtta aatacaaaaa tgactataaa tagattttta tttacacaaa
     4381 tctatttata gtcactatag tttatccaat aaaataataa aataaatatg tacacaataa
     4441 atgttattta cgtcttaagt atttatttgt tagattttta attaaaaaaa acaagctaat
     4501 gaacattaat gctaaatcta gcattatatt gctttgatct cctgtttgta cattttgacc
     4561 tacattacta tctaaacttt catctgtatc tatatttata tctggttttc cattcccatc
     4621 tgtatctata tttatatccg gttttccatc tccatctata tctatattta tatctggttt
     4681 tccatctcca tctgtatcta tatttatatc tggttttcca tctccatctg tgtctatatt
     4741 tatatctggt tttccatctc catctgtgtc tatatttata ttcggttttc catccccatc
     4801 tgtatctata tctggtttgc tatttcctcc attatctggg tctggtttac tatttccacc
     4861 gttatctgga tccggtttgc tatttcctcc attatctgga tctggtttac cattgccacc
     4921 gttatctgga tctggtttgc tatttcctcc gttatctgga tccggtttgc tatttcctcc
     4981 attacctgaa tccggtttgc tatttcctcc attacctgaa tccggtttgc tatttcctcc
     5041 attacctgaa tctggtttgc tatttcctcc attacctgaa tctggtttgc tatttcctcc
     5101 attatctgga tctggcttat ttagatttgg attacctgta tcataacctc ctgagccagt
     5161 atctacattt ttatcaggct tccaataatc atctactcca tcattatctg tatctattgc
     5221 tggacgatta taatctgtat cagggtttcc atctccattg gtatctatat ttttatcagg
     5281 tttccaaata ccatctccat ttccaccttc tgtactaggc ttccattcac ctgtattatc
     5341 agtatctatg ttaatatctg gcttccaatc accactcgta tctatattga tatctggcct
     5401 tccatcacca tcagtgtcta tatttatatc cggtattcca tccccatcta catctacatt
     5461 tgtcatatct aactttaact tcttttcatc ctcactacct tcaatgtaat ttatatcatc
     5521 tccaatatat tttacagtaa tagtttgttc agtagtaaaa atatgatgat tgctatctaa
     5581 aggtctccat tcaatagatg cagtactata attatgactc tcactaccct tattatgagt
     5641 ttttaattct actggatctt tatattcctt tccattaata tagaattgta cgtaacctct
     5701 tggagaggca caatctggtc cttctttctt atctggtgaa atagtaacat ttaatgtaaa
     5761 cgtatctgtt ggtttaaaaa catcagtttt agctttagac tcttctacaa ctaatgaagt
     5821 ttctgtatca gcaggaataa tttctgcctt ataatatgct ctatgccccc aataagcatc
     5881 cttaaaagga tatatactcg aaaactgtgt tgatgtaatg cttaattgat atttcccagc
     5941 atcaacttgt tttgtaagat catcacttcc taaatttata tctggttcca tcgtttcctc
     6001 atttaaacgt tgagaactaa tagtcataaa ttttttatct gtgagttttt cacctttagg
     6061 agtagttatt ggaataccac catcttttaa tagccaatct aaaaatgatt tttctacgtc
     6121 ttcttcaaat ggtaatccat catatctttt aataatcaaa tatggtggag tatcatcaat
     6181 agtaaattct tcatattgct ttaaaaattg agaacctgaa cctatatctt taatataaaa
     6241 atcatctggt tttagaactt ctccagtaat tttatctata acaactaaat taacagatac
     6301 ttcagatcca gtaaatttat cagagaacca taagtaaaga atcccttgag catctgtata
     6361 actaggtgct ccataaggat aaatttttcc atcaattagc attttaaaat catcaactag
     6421 tgtagtacta actttatctt gccctaaata cgttagagat attttattca taaaaacttt
     6481 tgttttcttt tctaaatcac cgtatgcaac tgctccacct aaacttttga atgttgttgc
     6541 ttttaatgaa ccacctgtta ctataacatc tcccgttgta gcacttaggt caaaaatcca
     6601 atctcccact cctgtcatat aaggtaaaat cgttcctcca gttacaagta tacgatatcc
     6661 tctatttgtt cctggattaa cacatccatc cccaaatgca ctaccatgtg cacctccata
     6721 tgaataggaa agtccaccat taattgtaat attcccacta taaccagaac ctgtgctagg
     6781 atctactact gagggactta atgcattctt tgttgttgta tagtatcctc cacctattcc
     6841 agctccatgg tatgcacctt tagcagttat agtaccacca ttgattgtga tatctccacc
     6901 actaccatta ccgcctccac ctattccagc tccatatcct gtattacgac tcgattcttg
     6961 acctatagca gttatagcac caccattaat aataatattt cctccacttt cagtatttcc
     7021 accgccaata cctgcagaat aataatttcc aacaactttt aaacttcctc tattattact
     7081 atctagtagt gtaaggcgat ctcctttttt taacttgtct ccattttcta gagttacatc
     7141 tctaggaatt tttccaccct cagaaactat aaactcgcct tcaatatctc tatttacaac
     7201 agaatcatca ataattagag tagtaccttt tcctgctctc atacctggat aatatacatc
     7261 acctgactct agcttgtttt cactaccatc ttgtaatata acatgtgcat atgcaccacc
     7321 atctttatct ggtgttaaag taaatgggct attagatgca gttttaatat ttactccatc
     7381 aaatattaat tcagctttta catctttagg tataacaatc ctatgtgttg ttggagtatt
     7441 tggattatta ttttgaattg tcatttgttt tccactaaga atagttaaaa cgccacttgc
     7501 aaatttaaaa tcgacattta tttctccacc actaatttta aagtctccta cagatgtagg
     7561 atcttctgca gtggcttctt ccacaactaa tgcattcata tctccttctg catttcctgc
     7621 attagaatct tcttctgcat ttcctgcatt agaatcttct tctgcatttc ctgcattagc
     7681 atctccttct gcatttcctg cattagcatc ttcttctgca tttcctgcat tagcatcttc
     7741 ttctgcattt cctgcattag catctcctcc tgcatttcct gcattagcat ctccttctgg
     7801 atttcctaca ttagtatctc ctcctgcatt tcctgcatta gcatcccctt ctgcatttcc
     7861 tgcattagca tcccctcctg catttcctgc attagtatct ccttctgcat ttcctgcatt
     7921 agtactttct tctatagtat ctgcgaaagt atttgacgca ttaaatgatg ctactgatcc
     7981 aagtcccatt gagatactta aaatcattga tagtgctttc tttttacatt tttgttgcat
     8041 aaattccccc tccccttaat aatttttaat atacactgta tacatcctta tatacactct
     8101 aataattctt aatatacact gtatacatcc ttatatacac tctaataatt tttaatatat
     8161 acttaaaact tatatttgtc aatgaatata cagttttttt caaccttata tattataagt
     8221 attcattatt tgctaaataa ctacaataaa aattttaatt atataaaatt tatttaatct
     8281 tttatataat aatacaaggg gtaattaatt gaaaaaacta gtaaaaatat taataaatat
     8341 tatttgcatt attacgctaa ttttctctag cctttcgatt tacataaaat tatctgaata
     8401 taaaaaagct gatgaagtat atacggaact cagagaaaac actatcaata atagcaaata
     8461 tcaagaactt tatgataaaa ataatgatta tagattctgg cttaaaataa acaacgtaaa
     8521 tatagactat cctgtagtac aaggatataa caatgatttc tacctaactc atgattttta
     8581 taaaaattat cttcctttag gtagtatttt catggattat agaaataatt ttgaaaatga
     8641 taagagttta atagtctatg gtcattatat gaaaaataaa actatgtttg gtcagctaga
     8701 aaactatact gatgaagtat ttttcaaaga aaataattta gtagaaataa attataaagt
     8761 acaaacttat acttatgaaa ttttttcagt atatactgct gacttaatta acagagatta
     8821 tttaagtata cactttaata ataatgatga gtttaaatat tctttgaatt atataaccta
     8881 aaaatcagta cacaaatctg atataaaggt agatatttca gataaaatta taactttgta
     8941 tacttgtaaa tatgaattta aagatgctct tactatagtt catgctaaat taatttcaaa
     9001 aaagagacct ataagtaggt ttgtgtaaat gcagacttat ctacagtctt ttttgaacgt
     9061 aaaattggta agtatagaat aatattcata ttaaactttt gtaggcaaag aaatgaaaaa
     9121 tcaaagagaa ataattatta cagatttaga ttaccaagct gaattaagaa agtgtaaaac
     9181 tatggaggat gtagttagtg aagataatat ataatagttt aacttataaa ttatcttggt
     9241 gatattaatg aagtttcaaa gtatatatta tttattgata taaataaaat taaatctgtt
     9301 gctaatagat gtacctttgt ttggagacaa actattgaag aaatataact aaaatgttga
     9361 agtagctacc tgactttatt ttgaaatgcg aacaagattt tggcattaag ataatttaga
     9421 aagaatcact ggtacacaag gatgtgaact tagaatgaat agaagtattc aggcataagg
     9481 agctttcacc caaataaaac atagtatgaa ctttaaaaga attctaatca gaggcaatca
     9541 agatattctt tcagagttta tacctgtagt gttagcctat agtatttcta agtttcacaa
     9601 ataagataat cattaataaa tgtagtatgt atattcatcc tctcaaaaat attttttaat
     9661 cttacacttt gtaaattatt ctattttaaa atggtatttt tataccttta tttcttatga
     9721 ccgttttcaa gctcaaattt tgcataaata taaattaatg aaaagcaagt aaaaaaagaa
     9781 ctgtcgcaca gcaatttaaa attactcatt cgacagtcct tatttcgtgg atttaaatag
     9841 tggagaagaa tcacaagaat aatacccacg attaaacctt tatacaatac attttatatg
     9901 actttaccat cactaatagt tattatacaa tcagccatct tagctatttc atcattatga
     9961 gttatcataa ccaacgtctg cttgtattca tttacacaat actttagtaa attcatcacc
    10021 tcattagttg ttttactgtc taaatttcca gtaggttcat ctgcaaaaat tattgatggc
    10081 ttattggcaa gtgatcttgc tattgcaact ctttgttgtt gaccacctga taattcatta
    10141 ggaaatttat taatctgact ttctaatcct aacttagtta ttaaatcatt aatataatta
    10201 ttatctatct ttcctttagc aattaaaata ggaagaacta tattatcata aacattgata
    10261 acaggtatta gattatagtt ttggaatata aacccaaatt ctttacttct aagattagat
    10321 agcttttcat cacttaaagt atataaatct aaattatcca taaatacatt acctaaagtt
    10381 ggtttatcaa gccctgccat acagtgaagt aatgtgcttt ttccagaacc actttgtcca
    10441 attattgcac taaatttatg gggttctatc tctaaagtaa ttccatcaac agcctttatt
    10501 tcattttctc cttttccata tattttttta atatctataa cttttaacat cttcatacat
    10561 ttacctccca aattattcat tctcttttat accttcaata atattcatac tttcaaaatc
    10621 tctattactt acaactactg ctattaaaca tacaaataca gatatagcaa agaatagtaa
    10681 agattcctta attgggaatg taaaagacat aaaattctct attccatagt ttatatacgc
    10741 atcattattc caatttgtaa atttaactag atttataaat gatggaatca tagctattat
    10801 aaagctaaaa actgcatatg ctaatgcttc atatataagc atttttttca tatttttaag
    10861 actaacacct aatgctctaa gcgttgaaat ttcttttttt ctaattagta gatttgttct
    10921 tatagtacag aaaatattaa ttgatgctat tattaaaact agtgcaatta ttgctatttg
    10981 tgatttaatg taacttttat atatactttc tgacatttca tgataactta atctactatt
    11041 aaatagagac cctggtatac ttcttgaaat tttctgtatc tcattattaa caatctcatc
    11101 atatggattt tctaaattta tgcctaattg agtgtatttt tgttctcctg ttatgttttt
    11161 agagtgaata ttacttgtta taatttctag atctggcata aaatcgccat ctcccatagc
    11221 aatccattca tcctttaaaa ttacagccac tcttaccttc atctctttat aaacaattgt
    11281 attattttct tcaacaggaa tttttacagt tattatgtct cctatattta attctttgaa
    11341 tataggcttt atagtatgat catcaactat atcataaaaa taattatata ctgctacatt
    11401 tggatatcca tcagtgtcct ttttaatatc atctaagcta ccttcttcaa caaagtcatt
    11461 taacttttca tctatataat catcatcata aagctttaaa actaatttat cttccattat
    11521 ctcttttttt tctactccat tataggttgt aaattctttg tttatatcct tattattaaa
    11581 agtaaacatt ccatttgtta tttgaatttt atgtatactt ttaacaccct taattttttc
    11641 tatattctct acatcactat ccgtgtattt tgatatttgc gggtctgcat ttactccaaa
    11701 ttgcattgtt atattatatc tattttgcat atcttcaatt ttactgttga cctcttcttg
    11761 catacttgag aatgtagtaa tgaatatata tcctcctaaa gcaatagaca acatagatat
    11821 agcagctcta accttatttc ttccaatatt tttaagtccc ataaatccat aaaatccaaa
    11881 tattttgctt actagtctgt ctattccaag tctacttctg tgatttttaa ttttgtctgt
    11941 atttattatt gattcaatag gtgatatctt gccgatttta aaagttggta taatacaaga
    12001 tataaaaaca gaaattattc caaccaatat agcttttata actatttcat tatttatata
    12061 taatttaggg ttaagaccag cttcactgta taaaacttcg ttataattac taattcctat
    12121 atatgaatat gtaaccccag ctactaaccc aagtagtata cctattattg ttataattaa
    12181 tgcttgatag attatcatac accttacgtt tcttttcttt gcacccatca gtctaaacag
    12241 tcccatttct tttactgatt gatttagtgt aatattgaaa atattaaata tgaaaattat
    12301 agatactgta gttattaaaa catttctttt aaaaacattc ggatcattct tatcatcttc
    12361 tacataacga agttccctta caagaggtac atttggtaga aaactttttt gtcctaactt
    12421 atattttttc ataagataat cacattcacc ttcaatattt ctccatccac ttttaaaact
    12481 taatatacta ttataactaa tcgcatcatg aggtataatg ttatttgttt catcattgcc
    12541 ataagttact gcttcgtatt gccaaaccac atcatagtac ccttttggtt tttccataac
    12601 tcctactatt ttaaattctt tatttataga aaataatcga ttacttccgt tagtatcttt
    12661 atagttcttt tttattgtta aatttaatgt agatcctact ccttcactta aattcattgc
    12721 ttctagtgct tttttctcta atactatttc attgttgttt ttaggtagtc taccttctat
    12781 tattttgttg tatctacttt ttagatactc ttcgtttgat gaagttaata taaatgagtt
    12841 tcctttttta tctgaaatac gtcctaaatt ttgtaccgaa ttaccctttg atactttttc
    12901 atcagtttct aattttttag catcatcaag tgtcaaatca ctaaactcta catggtatcc
    12961 actgtaaagt tcatgtattg ctactacatt gttttcattt tgtgaatctt ttataacact
    13021 aggtccaaat atcaacataa cacctaacat aactcctatt attaaaagta gtgttctaag
    13081 tttatttttc tttaaatatg ctagtgacat ttttaagtaa atccccatat aatcctccta
    13141 ttttactata aattatttat ccaactcatc tgttaagtag attggtggat attttaaatc
    13201 ttttaattct tcattatttt ttgaagctta ctaccatctt cctcatgata aacttgcagt
    13261 atcaccttat ttacatgtag tgcataataa tcaccactat aaaaatattg gtattcataa
    13321 cctggataat ttttgtaaaa tgatttataa agtacccatc ctaattctct tttgtatact
    13381 tttcttttgt aatacgctct atatcatcac ctgaaactcc ttgatatgtc atatatttat
    13441 ctatatattt ttcagcttca ttccattttc taaaatagtt gttgtatata ataaatccta
    13501 ttatggctat aatgcttata attaaagtta ataaaatagc tttgtatttt ctcatagtga
    13561 atcttactac ttcaatttaa attctttaat aagttttaat tctaaagact tagttttatc
    13621 atcaaatttc ttaacttgaa tttttatatc tcccaaatta tcaacctcta tatttccttc
    13681 acctttatca aatacttctt caatttttct aaaaaattct ttctcactta tttctacatg
    13741 aatcaatgat ctatatgtta taaatagcca ttatgaattt atcatcttct gacagttttt
    13801 cattataaga aaaatcttta acacattgaa ttgataatat ttcctttgtc cccttcttgt
    13861 ccttagtcat tgaataatgt aaaacttggc taggttgttc ttttgtatac tccaagtttc
    13921 ccaaagacaa aacaaaactt ccatctgatt tattttcagc taccctaaga ccactatttt
    13981 ctattgattc tgatattttc tttgacaagt cttcttgata ctagaaatcg gttcaatagt
    14041 atatattttt tcatttgtat ctgaaacctt atttgtgcat cctgttatta aacctagcgt
    14101 taagcttata gctataacca tagttattgt aattttttta tcttcatata atccccctta
    14161 tatattgaaa actcgttatt tctcataaaa aaaagacgct atctttttct attaaaagat
    14221 aacatcccta tatgtttagt atcaatatat gttccccaac tggtaggtta atcgacccaa
    14281 ctatcaaaat tttgatttaa tggtatataa atattcaata taaatttgtc ttttttatct
    14341 tcaaatgata aatctcctct atattttttt atagaagatt tgatgcttta aatccctatt
    14401 ccatgtacaa gtttatcttt tttatctgtt aataataaac ttttattctt tctaattgaa
    14461 tttattttac tattctcaca tttaattacg aaataggact ttgagatagt tccttttatt
    14521 tgtatatatt tatcaatact tttatcatgt atcttatcgc aagcttctat tgcattatct
    14581 aagtatttgc aaatatatta gatacatcta ttggttttat aaaattcact ttggaaaaat
    14641 tgatatcaca aatgaattta atttttcttt tttcacttac atcacttttt tcatttatta
    14701 ttatatccaa tataacatta cctgtattgt aaattgattt aaattcttta atttaatctt
    14761 ttaaactatt tacataccca tcaattttcc ttttttatat ttgagatttt ctatacaata
    14821 tatatgatta tttatatcat gataaagctt cttaacttta gcgtgtgatt cttgaatact
    14881 tagataatga gaatactgca tatctaactt attttttatt acttcatttt gcaattttaa
    14941 cttattttcc ttaattattt ttataaacac tataataatg actaagctac tagatagtat
    15001 taacctaggt atcacaatat acccaactat atatatttcc taatacccac caaattgata
    15061 catttttcta tttatataaa ttattaatat agtaaataaa tttgttatta aagcaacaga
    15121 taagtatata tagtttattt tattatcttt atctagtccc aatcttttat taataaattt
    15181 aaatatagca caagctacta tataattatt attataagat aatagtatat atctacttta
    15241 gcattatcat aactaaacac taatagagct tcctctgatg atattacatt acttgtaact
    15301 acaaaaaata aatttataga tataacatct tttattaaag ggtgatatac gtcaaataag
    15361 aaaaatgaaa ctatatattt aacaattcct atcttataaa aataattata gtaagttccc
    15421 aagtaataaa tatcaaataa tagattatat catatagatt tttcttcata ttataatcat
    15481 gggtcttatc aacgttaaat aatataatga ttttagttat aagataagct aataatacag
    15541 taaaaaaaga tattttctta gtcttatctg tatctttatc gtaagttaat atacttttta
    15601 gtatcattat tggtgtaaac aatgataata ttaataatat tttatttata tggtttagca
    15661 tattctatca ccaataaatt ttagaaacct ctcttttata tctttatatc tatatctgct
    15721 aataggtact tcttcttgac tgtctaatat tgcagtattt gactttatat tttctacata
    15781 gtttaagtta attatataac ttttatgaca tcttacaagt tcctctatat ttaaatcttt
    15841 ttctattttt tctagtatac atatagcatc aaaagtttta ttttttgtat gtattagcat
    15901 gttctttttt tgaacttcta tctatttttt tgctagagta gattttgtat gtgttagact
    15961 tatttttatt tttttcaatt tttttgatac atgttaatat gtgtttttct agttcttgaa
    16021 aatttattgg ctttaataag tatcaataag ctcttacttc atatctttcc tgtacataat
    16081 ttattagaga tgttataaat attattatct acttttctta tgtttcttgc gatatctata
    16141 ctatttagtt ctggcatttt tatatctaag agtagtgtat cctctcaatt aactttgtaa
    16201 tggttcttct tttgagctat atttttttaa ttcgatattc tttgttttta ttttttaata
    16261 tattatcaac ttgatttttt attacgattt gtatttcttt ttcatcatca caagctgcta
    16321 ttgtaatgat gacctctcct agtattgtat ttttatttag attcttcact ttaggttaac
    16381 actttttaaa tgtatttatc aataatattt aaattaaaaa tgtataaaaa tacctatatc
    16441 caattggata taggtattcg tggatttcaa tggtggatac gaggggagtc tataagtggt
    16501 tatttgattg ttttgttggt ttttgtgaat gtaggtatat agctatttag ttatgatatt
    16561 agactgattt ttttggttat tttttattgt ttatttttgt ggttggggta ttattggggt
    16621 ataactttta aagtttataa attgagtcat taataaatat ctattgttta gtcaatctat
    16681 aatataataa atcttaaata gtgtaactat tctaagtagc tgctattttt attcatacat
    16741 atctttatat acatttatga gattcaagta tgtacattct tattctctaa tttttaaata
    16801 tattatctta aaatggtaac agttctacat ttaattaaat ttatatttta ttgtacttat
    16861 gtaaatataa actaatctat tctctaaata tatattgtga tataattata tataaattaa
    16921 aataggagta ttatgtaaag atcttcgcta tactcttata gaaaggatac ttaatatatg
    16981 gctgttaatt acctagataa caacaattta gaaaatttat atgatgaaat gcaggccgta
    17041 tatcttaatg atgatagacc ttggataatc ggatatagtt ctggaaaaga tagttcttgt
    17101 gtagttgaac ttacatttag aatgcttaaa agactaccca aagaaaaaag acataaagag
    17161 atttatgtaa tctcatctga tacacttata gaaaatccaa taatacttga ttatctaaaa
    17221 aataatatag acaagataaa tgaaagtgct actgaacatg atttacctat aagtgcacag
    17281 attgtatacc cagaacttaa tgatagtttt tgggccaata taattggtag aggttaccct
    17341 actccaaagt ctattaaata tcgttggtgt actgaaaggc ttaagataaa accatcaaat
    17401 aaatttataa aagaaaaact tgaacaaaaa gatgttattg tactgcttgg cgttcgtaaa
    17461 gaagaaagtt ctgctagaaa atcgagaatc gaaaaaagag agatagaggg ttaccttctt
    17521 accccacatg aaaccttaag aggtaaaaat aagttagctt atgtgtatac ccctatagtc
    17581 aattttagta cagcagatgt ttgggatgta ctctatcatc aaaatgataa tttcatagat
    17641 tttggtggtg aatttggacc atctccatct acctcatggg gaactgacgc tatggaatta
    17701 tttcagatgt atatgaaagg ttctggtgac tcagatgaat gcccatttat agcagatgaa
    17761 gctagtgcta aaagtagctg tggaaatagt aggtttggat gttggatttg tactgttgta
    17821 aaagaagaca aatcattaaa tggatttatt gaatctggtc atgacgaatt aaagccactt
    17881 ttggaattca gaagttggct aatttctgag agagataaac ctaaaaatcg taaaaaacat
    17941 aaaagaaatg gctctgtcat caaaaaagat ggtagaatca tgtttggacc atttacattt
    18001 gaagcaagac aaactatttt aagaaaactt ttagaaactc aacttgaaat gcaaaaattt
    18061 tatcctgatt tacaacttat tcaattagga gaacttaaag ctatagatga tatttgggat
    18121 aacgaagaag acttaactgg taatatatta tcaaaaatat ataaggaagt tgtaggcaaa
    18181 aacctaccat ggtctgaata taaaaaacca gtatttgatg accttacttt aaatattata
    18241 tctgaaaaat gtagtgagta tgatataaat attgatttat ttaataaatt aatgatagat
    18301 acaaataaat acaaatattt tagtaataat actaaattaa aaacttccat agaaagaata
    18361 ttaaatcaac agtggcttca tcaagatatt attgaaaaga ttgaagaaga aagcaacaag
    18421 gagttaaaat atgaaaataa ataaacttgt attgaaaaat ttcagatctt atgaggaaga
    18481 aaccaccttc aatctaaata ctactagtga aaaaaatatt atattgatag gtggtaaaaa
    18541 tggtgctggt aaatccacaa tatttgaggc tataaagcta tgtatatatg gacctatagc
    18601 ttataaatat caaggtttca actcttcata tatatctcga gttaaatcta atataaataa
    18661 taattctcta agaaatagta aggttgacac cttagtatca gtagatatag aaatcagtga
    18721 aggtactgaa aaaaatacct ataccttaat tagacaatgg acttttaaag ataaaaaatt
    18781 aaatgaaaca ttttcagttt ataaaaattt ttcatttaca ccattaaatg ctgatgaact
    18841 taattatttt gagaattata ttacatctat tatttctcct aaaatatttg actttttctt
    18901 ttttgatgga gaacatttgt atgatttttt tataggtaaa aattcaaata tacatctaaa
    18961 agaatcttta ttatctcttt gtaattttga tacatttgat attttaaaaa aaatgttaat
    19021 ttcaactaac agatccaata agaatgtttc agatgagatt aatattataa aagatgacta
    19081 tttaaattta gaagttgaaa tcaacaactt aaactctcaa gaaaaaaatc tatcttatga
    19141 attagaaaaa atttcaagtg aaattgagaa gttacaacaa gaacaattaa aaataaagaa
    19201 agaattcagg aaaaaaggtg gaattttagc agaagaaaga gaaatgctta attctagaat
    19261 tgctgaatta gaaggaaata gatttataat taatcaaaat ataaaagatt tttgtaatga
    19321 catacttccc tttttaattg taaaaaaaca aatattaaac ttagaaaaac aacttaaagt
    19381 agagaatgat agtatattat attctcatct taaagataaa ttaaatattg agtatataaa
    19441 aaatctactt tcagataaga tcatgtcttc ctcattagat gaaatagctc taactgtttc
    19501 tgaggcttta atagaagata taaaaccaga tagttatgaa gataactttg aatctatcca
    19561 taagctttct aatgatgaaa gtagtaaatt attatctttg ataaatacca ttttaaattt
    19621 tgataataat tctatcatta attcctttgg agaacatcga agtatttcaa atgaattggc
    19681 agacataaga cataagttaa atactagctt taaagatgaa actttgaata catatataaa
    19741 tgatatatct agtttatcag ataaaattga ttctttatta aaatcaaaga atttgctagt
    19801 tacttcttta gataaattaa gacttgaaat agctgaaact atcactaaaa gagacaaatc
    19861 taaggctaaa tatatatatt tacttcaaca taataatatt gttgatatat cttctaatct
    19921 tatacttatg ttagatgaaa taataacaac attaacagaa actaaaatta aactagttca
    19981 agataatttt atgtatatat ttaaaaggat tattcaaaaa gacaatttta ttagttctat
    20041 agatattgat gccaacttta atatttcttt atatataaat aaaatatata actctttaga
    20101 acttgaaaat ttagtagaaa atataggatc tgaagaaatg gagaagaagt tgggaaaatt
    20161 attttttgag gatttattta acttatatcg tgtaaaagat aaagatgatc tattcaatgc
    20221 tataaaaaat aatactcaat ctacattttt aaatctaaga actaaagttg acatagacga
    20281 attctctagt ggtgaaaaac aaatatacat tctttgttta tattgggctt tacttaaatc
    20341 ttcagagata gaaataccat ttattataga tacaccttat gctagaatag atgatactca
    20401 tagaaataat attactagtg aatatttttc tacaataagt gatcaagcta taatactatc
    20461 tactaatact gaaatagatg agaaatcata taagataata aagcctaagt taagtaatga
    20521 atacttgatt gaatatgata ataaaaataa aaaaactata caaaataaag gatacttttt
    20581 cgaggtgtaa ttatgggatt tagacttaaa acatccatac aaacaaaaga aatatttgaa
    20641 gaattaggat ctagaatgaa tttgaaacca tttgctcttt gcaaactagc tatctcaatc
    20701 tcactaagta atagtgagcc aattgaaaac tatgaaagca tcgataataa tggtcttgaa
    20761 cttaatagac aaactataac caatcaatat gatactctat ttaaaacttt acttgaacag
    20821 catgcaggta gacatttaag tgatgatgaa tactttccta accaagttaa gcttcatata
    20881 gatagaggtg ctcttatgct taaaaacaga tataattatt caagcaactt agaacacttt
    20941 atcactcaaa tagtacagga aaataataat ctataaatta attaatattt attaaacata
    21001 aataaattaa aacatgggat agacaataaa taaaattgcc tatcccatgt tttaattata
    21061 agtatttttt ctaaattcat ttattttatt tattaagttc ccaaaatgct ttatctctaa
    21121 tatatatagg tgagttctca ctaggcattt tgactaagct ttcatgttta gctagattct
    21181 ttatcttatt atatatgtta tcttcttcac ttttattctt agaattgaat atgtatctta
    21241 tgtctttatt atttatgtct gatacattat gtattatcca agttgaaata taattctgat
    21301 actcattttc tgaagttgaa aaatgactta gaagttgtgt tgatagaata gttcctactc
    21361 caaactctct accttccttc aatatatttt ttatagatgt aaagtttcta ctcaagaaat
    21421 tatcagcttc gtctactaat atcattttat ttaattgtct atactctcca tttccagtta
    21481 tatcacttga tccaagtgcc ttcatttgac tatagaataa atcaagagtt atcgcaacta
    21541 ctaaattttg tattcctgaa tcataatatg ataaatttat aactgtaact ccatttatta
    21601 aatcaaataa atttttagtc ttctcactat ttggctcaaa tatttcaaaa tcattaaaac
    21661 ttgaaagagc agcatacaat ttatcgtctt tttttatttc tcgatcatca aggtatatcg
    21721 ataatacatc ttgcattgta gggcatgatt ttacccatgt attttcatca tcttttttta
    21781 ttcctttttt ttcataagct ttcataatta attctctcaa aataacttct tgcttagggc
    21841 ctaagccaaa tgcttttgct attgtctctt ttaaagaatt cgctgtgtga acaggtagta
    21901 gtggctttat tctttcaggt attattaaag ttaatggatt ataaggtaaa tgatatattt
    21961 catatacctt agcacttgtc gcatctacaa aatcatcttt tatgtagtcg cctttataat
    22021 caaaaatcag tattcctatt ggtttaccat ttatgttatg tttttgttct ctatgaattt
    22081 gcgttactaa agatttagta aactgtgttt tcccagttcc cattgttcct attataccag
    22141 tattaggatg aggcacttta atcgaatttg ttggatccca aataagttct ttattattat
    22201 tttttatatt tccaaatata attttcatta aaccacttca atcataatct tttgttttat
    22261 ttagcataac attagtatct aaaataacat tcttatccat attttgtata cctattgtat
    22321 tatctaaata cttatttata agcatttctt gtataacaaa atcactctct cctctaatat
    22381 acttctcctt catttcctct aaatccatca ctatattatt atatccttct tgttctgaaa
    22441 gatttagtat agttatattg ccttctttgc ctaaattccc attataataa gttccctttt
    22501 taaatgatat tacagctcct cttcctataa attcatctaa atcattactt atttcataat
    22561 tatcattcaa caagtttgtt cttatatcac tatttattat atcatcccaa ttttgttcat
    22621 cccatatatg atataacttc attttttgtg cacttactat agcgagttgt atcataaaat
    22681 tcctgtacat aagctttgta aacttttggg aatcattttc gctttcagtc aagtactctt
    22741 ctattaaatc tcttgtctta ttagcctgaa ttattgcctt ttttatgaca ctttcattat
    22801 tatctccaat tttcacttca acaggataaa aatatacttt tattttatta tttttatttt
    22861 ctatcccaac aagtaataaa tcatctgaat aagatccagt atctcctgtt agtttcttaa
    22921 cagtaaacaa accacctgct tgttttaatc cagctccacc agatactcta agtatttctt
    22981 caagagatat tggtatccat attatatttg gatgataaaa ataagctaag cttattttta
    23041 tagctgataa tatgcttaat ttttctctag gaaactgaga tttactagat ataagcctta
    23101 ataaccaatc tccatttata gcattgaaat aattaatcaa attagggatt gtgtcttctt
    23161 ccactttaat atctttacta tttagaaatt cttcaattat aaatttatat tgttcagatt
    23221 ttctagtaac tgttatagca tcatatccac tagatgttgt atattgatca ctataatgta
    23281 ttattaataa gtcatttgaa ttctcatcat ccttaaaaaa atttaaatcc acttttggat
    23341 ctataaaagt aacccaatga gatgtcttat aaattttatt taaaaatgaa ctattgtttt
    23401 cacttattga tgttgtcaca ctaagattat cattaaatgg atctccagtt cctattgatt
    23461 ttgtaagtga attaaacttc attgaaatat ttaacagttc atttttagtt gtagccataa
    23521 acttagatcc aaatccagtc ctataagtat cctctaaata tattgatgga actcctgcta
    23581 tcaatccatt taatgctaca cctgttttta tatcatccat agagctactt gttatattta
    23641 catccttatc catttgatat aaagtcaaat gggaatactc atataaatct gacattttat
    23701 cttttttata aaatttaact ttatctctaa ataaatttaa tacatcttct tcagagtaat
    23761 tgtctacact taaatttaca ttaaaatgtt tttttatatc atttattgaa ttataaaatg
    23821 ctatttcttc aaatgaattt ataatacttt tatctccata tatataaata tctattgata
    23881 ttaagttatt tatttcctca cctttaccta atttctttat gtaataatca aatataccaa
    23941 gtaatacttc tttacaatca cctaaattta ttagctttat cttcattact gatttactta
    24001 tatccctaaa taaatatgta aaatgttcta taaattcatt tattttttcc tttgtcaatt
    24061 tagagacata atctctagat cccttatatc tactcatgtc atgatcaaca tagtatgtcc
    24121 actctggtga atgtctttga tctactacct tatataaact attcttacct ttatatatat
    24181 agggcattag atacttcgaa cccaatagtt ttaagattcc ttctttaact tcttcatcac
    24241 ctataacatt atttatcatt aattggtaag ccacatttac tggatgtaat ggtgttaaaa
    24301 ataattcttc ttctttatct attctatgta tagtccctac cttagctata ttaagtctct
    24361 ctttagataa tacttttcca ttttttatat cttcaaacac ttctaatata gtatttatat
    24421 aattttttga tatgttaact aaatccacat cataatatgc caagcttgga atacaatcat
    24481 ttactttata gtaacttata aggtttttgt atgcttcttt tattctggaa tctacatcca
    24541 attctattat tttatatttt tcttctaaaa tagtacaatg cattatatta ttttctatga
    24601 tatatttttc tatttgcaaa ttttctttaa aattttcttt tggaaaatat tcactagtac
    24661 cttgtacaat tttactatta cctaaatatt taaaactctc ctttcgttct ctctttaatt
    24721 tccaggtttt cattccactt atagaaattg gttgttcttt ttcttcttgt ttaactatgg
    24781 taattacaga ttgatcatat actacatcaa tttttataaa ttcaacatct tcttccaatt
    24841 caacattaag ttctaaatct agcctttctc cttcttcaag attaatttca ttttcaaact
    24901 catctatttg tatttttctc tcaattatac cttttgggtt tattactatt gtatcatcat
    24961 ctgtgttagt aactaacata cttctttttg aattaataac aattccataa ttacttttta
    25021 tatcatttaa tatattctca tcacaagata ctatacaaat tctaaattca tattttatta
    25081 taccatcatt atatttaact ttagtaaatg tagtttctga aatatttata tttatactta
    25141 tataagcttt atttccactt gcttttactt ctgtatatgt tttagacatc ttatctatag
    25201 aaaaacttgt tttttcaatt ttcttatcaa attttatgca taaatttata atatcaagtt
    25261 tgtctttatt aaataataat atgttttttc gttttgactt attttcaata tctggtttac
    25321 tccagagctt taggttttca acacattcta tacataataa ctctaccttt ttgtttttca
    25381 ttctttcttg agatgacttt atatctttat aggtagaata cttccaattc tcatctttta
    25441 aaagatctat accttttgaa tcaaaatgtt tctctaattc cagcttaggg tctccatact
    25501 gatgtataga gtttacaata gaaaacagct tttcattatc taatagtctt tcttttattg
    25561 ccttgctact tttgttgtct aacatattat catcataaaa taatccaaat ttactatatt
    25621 cactcttttc aattcttcct ttatttaata tatctaatat attttcatat tgaaatattg
    25681 atgaattatc ttctaatata cttttattca ttctatcaag tacaaaataa agtatatgtt
    25741 taatatcttc ttttaattta tcattttcta atttattttg tatgtccttt actaaagttt
    25801 ttgtatgaaa tggcatacct tctttttgca aactttctgt tcctcttatt aaactatcta
    25861 atgtcatatt atgtataaat aatatggctg aatccttaaa ttcatcacta gctacatttc
    25921 ctataagatt tctaagtcta attaaaaaat cattggttgt attattattt gaagcaacta
    25981 ttaattgaat accactgaca ttcatactaa aagtctgata ttttgatcca ttcattatat
    26041 tatatgtaaa tggtctacta ttactttctt tctctaaaac atcatacata attttaactt
    26101 gttcttctct ttcaaactgt atattaaatt tatcgccact ttttatttct ctagattcga
    26161 aatatttaac tagattttta gctagatatc tataaaattg atctgacata ttgtgcatcc
    26221 ccactatcac tctttttttc tattatattt aatttttcaa ataactctac tactttgctt
    26281 tgagaatctc tatcaaaata aattcctctt ttttcatatt cttcaaataa ttcctttaat
    26341 tttatctttg tcttattttt catacataat tttgtcataa ataacagttc ttcttgatta
    26401 attttcaata catttcccaa tggccctgct ttttttaaaa aatttaattt acaatactct
    26461 tcaaataaat ttttatacct cttatagtta gcctctcttg aagatttctt gaactgataa
    26521 tctattcttt tatgtaaatc acatatttct tcttttatgt tatcattctt atacacttta
    26581 gtttgttcat cataatcatc ccattgtaca tcagtaattg acttgacata agtatttttt
    26641 atatctatta tattttcata taacctaagt ctttcatttt ctgataaatt ttttataatt
    26701 ttatttaaat ctacataatc atacttacta atgtcattat tagtatttaa tatctctaat
    26761 gtatgaacat gactaaataa tattctaata tgactctcca acattttcca acccatgtta
    26821 taacttattc ttgttttaga tgctttttcc caacttaaaa taaaatatac tttttcagtt
    26881 ctatctctat ctccatcaaa aaagtgagat aattttattg ataattgtga tacatagaaa
    26941 aaataatagt actttaataa tctttcaaac tcgtttataa ttaattctgg ataattaagc
    27001 ataaattcta aatcttcttg gaataattta gacacatttt tacatataca tttataaatt
    27061 gatttagacg tctcttcatt ttcaagttca ggaagatttt ttaatataat aagttccata
    27121 atattatcag gttcatattc aaaacattta tttattttat tttttatagt tatattatct
    27181 gtactattta gtaaaacatc atataaaaat ttagacaatt ttttataata actatcagat
    27241 ggcatatgta tataatttaa aagctttgga tgaaatatat acatattttc ttcttcatcc
    27301 aaaaataatt ctcttattat actctcaagt tgtacactat catcagaaga attcacattt
    27361 atgtctttta taagtaactt tatatctttt agctgtcttt cttttatgtt cattttcttg
    27421 ttatatacca acctacagaa ttctccaaca caagactcaa atctttctac cttttcttta
    27481 agtttcgatt tttctttagt tgtagttgta tatgggagta taactatgtt tttgacacta
    27541 ttatgtctcg cgataccttt atctatcata taattttgtt taaagtattc tttatttatt
    27601 ataagttgca taccttcacc ccatttactc ttataaattt gaatttatca aattctttat
    27661 catatgttaa tttatattta ggcacagtat cttctaatct atcctctata tatagttctc
    27721 tgttttgatt tcctaattta tgtatcttat tcataaatac tacaaaattt atgtaagtat
    27781 atttatcatt attgtttggt gtatatccat attttactct cattagtaac ttatataaat
    27841 taaaatctat atccactgta caagtatctt gattttcttt ttcatcattt ttatacccta
    27901 tctctaaact aggcttaaac ttgtgcaatt cttcctcagt acattttctt aatttgctta
    27961 aatctggaat tatatttagc ctttgactta ttttatatct catctgattt tttccaatgg
    28021 acatatttat tctgtcatct tgaatacgtc cattccaact atacaaagct tctttaatat
    28081 catcatataa attacttaaa taagtttttt ctcctttgtt aaaatagtat aaatttctca
    28141 tgtaacttat atatatatta tctcttaact gtaaattatt tttaggtata aatatatgta
    28201 gtcttataaa tgtatttatt atattgtatt ttaatatttt cctactcagt tcgttctttg
    28261 aagaattcaa agccgactct attatttctc tatttgtcat agaactttct agataactgt
    28321 ttttacttaa attcaggtat tgattaaata gtattgtcat atcttttgta ttactaagct
    28381 taatgattat attatctagg ttttctgatg tgatatttat agggtcaatt ttatttactg
    28441 catttaaaat ctgagataat tcactatgat tatataaatt agatacaaat atatatttta
    28501 tgaatgcttc ataacttagt tcttctacaa acttaattaa gtctttatta tttttattgt
    28561 ctaaatcaac attaacaata aaatcatata taaaattcaa aagagacctt gttgaaatta
    28621 taattttata tttaactgta gattctatca atatatccac caaggtttct ctcactgagt
    28681 ctctcattaa catttcataa ttatttttaa tcggacattt ataattgaca atacaatgtg
    28741 tacaatttgt tttataacta tttataaata tattttgatt atcttctgct attattttat
    28801 taattataga ttctatatat ctagatttag gtttatctgc attcaaagta tatatatgat
    28861 aatcactaaa attaacaaaa tgaaaattcg aatttttatc atcatcatct gatatagata
    28921 tatcaagtat tcctttattt tcaacaaact ctcttaattt agtaaattta ttaacatatt
    28981 ctgattcaag aaaattacta agtgccccta aatttattgc taatactaac tttttatctg
    29041 aattatccat tttcttatct gaaaaatcat caagtacatc attaagtgta tctattgatg
    29101 ttttatttgg ttcaaaactt tctgtagcat cattatgaat tataaatttt gacataattt
    29161 ctggatattt gttatttaaa tatgatatta aatgcgattt tccatctcct actccaccac
    29221 ataccaatat caactcagct ttattagaat cagctgtata ttttataata tcaagtaatt
    29281 cgttttctac ttgtctttta acatgcatat attttttaaa actactaaaa tctgaaatat
    29341 tttctactgc ttcctttgat gattctttta atttctttaa ttcatctatc aaacaaccat
    29401 ttgacataat tttaaaactc cttctaatat actcttttat actacactta tattataaat
    29461 gctatttatt tctttgagat cccttt
//
LOCUS       DAMKNB010000043        29357 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.045, whole genome shotgun sequence.
ACCESSION   DAMKNB010000043 DAMKNB010000000
VERSION     DAMKNB010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 29357)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29357)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29357
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.045"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            complement(156..443)
                     /locus_tag="PC494_002157"
     CDS             complement(156..443)
                     /locus_tag="PC494_002157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HDF3912656.1"
                     /translation="MEENIINLIDENGVESQFEIILTLEAEGKEYAILMPLDDEEAEE
                     ALIFRIDEDEEGEILIPLESDEEYETVVAVYTAIMEEEGLNYDEDESNGLN"
     gene            complement(521..946)
                     /gene="ruvX"
                     /locus_tag="PC494_002158"
     CDS             complement(521..946)
                     /gene="ruvX"
                     /locus_tag="PC494_002158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HDF3912657.1"
                     /translation="MLDGRIMGLDVGDKTIGVAVSDLMGLTAQGVKTIKRVGKKKDIE
                     ELKAIIKEKQVNKIVSGLPKNMNGTLGPQGEKVIKFCELVKAETGIDVEFWDERLSTV
                     AAERSLLEADVSRQKRKKVIDMLAAVIILQGYLDFKINS"
     gene            complement(1152..3323)
                     /locus_tag="PC494_002159"
     CDS             complement(1152..3323)
                     /locus_tag="PC494_002159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3912658.1"
                     /translation="MRKKIMSLFAIVIMIFVSTASYGFAEEKGKVIFIDMNRTNLGSM
                     MNIPILKNEIEKRGYVALMNIRGDQGTDDRRSYASMGAGTRASVTTEDYINFQKVDQD
                     TAKAFEVATGQKAKEINDLGINRSINENLEYGEYGANLGSLGKTLSENGLKTSVIGNA
                     DIIENNQLVKNRNLCLVAMDQYGRIDSGNIDNINKKDSKMPFGISTDYDKLLDETKKS
                     YKNSDAIFVELGDTYRLDMYRLNLNDNTYDTMKKNIVKNINKYLEQVFSMVGENDTVY
                     IASAFPSDLDYKNKRRLSPIIKFSGEGKGLLESATTRKAGIVANLDVGVDILGTFGLE
                     NKEMVGRSYTLVNKEDNISYLKSLYERIVSISSIRSTIINGFVGVISASWVIAMFAIF
                     FRNYMPHKERVFKVLKEFIKLGIIMPLSFMLAPLMNFKTPISISLGIFATTLILYLLG
                     RKLFKDNDIKHMGFFATLTILVIVIDSVFGTYLMQNNIMSYDAVIGARYYGVGNEYEG
                     VTIASAVFGLAVLLHYKKVSKLLVVIFSLIILITSAYPSMGANVGGAISECVAYLLFI
                     MLIYDIKIDFKKAVLLAVSAVVVVFAFAALDILSGSESHLGMFVQRIFLNGPGEILQT
                     FGRKIQMNMQLAQTSVWVNILLVGIGVIAVLIFKPSRHFRKIMNNFPILFKGFIASMV
                     GCIITLLVNDSGIVAASTASIYILIPLIIISINMIIFEKNN"
     gene            complement(3333..3590)
                     /locus_tag="PC494_002160"
     CDS             complement(3333..3590)
                     /locus_tag="PC494_002160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HDF3912659.1"
                     /translation="MEKDLDYTMKFEGIPEDRMSVGDTIDFVYKALVEKGYNPINQII
                     GYLLSGDSSYITSHKNARAIIKKFERDEILEEVITHYLNRK"
     gene            complement(3615..6254)
                     /gene="alaS"
                     /locus_tag="PC494_002161"
     CDS             complement(3615..6254)
                     /gene="alaS"
                     /locus_tag="PC494_002161"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HDF3912660.1"
                     /translation="MEKMGLNEIRSKFLEFFESKGHYVANSYSLVPNNDKSLLLINSG
                     MAPLKNYFSGVEVPPSVRMCTSQKCIRTGDIENVGITARHATFFEMMGNFSFGDYFKR
                     ESIKWGWEFVTEWLNIPEDKIWVTVYEEDDDSYDIWAKEMNFPEERMVRLGKDDNFWE
                     IGTGPCGPCSEIYFDRGEEYGCDNPDCKPGCDCDRYLEFWNHVFTQFDRDEEGNYSLL
                     ENKNIDTGMGLERMGCIMQGVDTIFEVDTIKSILEAVEKLTGVKYGENPKNDISIRII
                     TDHIRAVTFLVSDGVLPSNEGRGYVLRRLLRRAARHGKLLGVKELFLQKLIDEVIKVN
                     DKAYPVLVEKESYIKKVVGIEEEKFNETIDQGTEILNSYIEVLKNEGKTVLSGQEAFK
                     LYDTYGFPIDLTKEILEEEHLSVDEEAFNEEMEKQKERARNARGNMDRESWKEDPLSK
                     LESTVDSTFNGYSEIYGEGTIEAIVKDDELVQSAEEGDKVSIVLDNTTFYPEGGGQVG
                     DCGLITNENLVLEVLNTKKGANNSIKHIGIIKSGRISNGDKVKTLVDRETRMSAARNH
                     SATHLLHKALREVLGEHVNQAGSLVTPERLRFDITHFEAISNEELKVIEEKVNNVILS
                     SLDIKCDIMNIKEAKEKGATALFGEKYGDEVRVVSMGDYSTELCGGTHLTNTSQVGMF
                     KILSEGGVAAGVRRIEAITGKAVYEYLKERDGIISEVCVNLKSKEDNLIQRISSLLEE
                     NKNLSKELHDMKAKMSLQSVDSIFDSKVEVNGVNLITNKFEGMDMDTLRETADNLRDK
                     LGSGVVVLANVVDDKVNFVVTATKDVLDKGIHSGNIVREVAKIAGGKGGGRPNMAQAG
                     ASDVSKVDQALSYASEVIKTQVK"
     misc_binding    complement(6322..6560)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(6703..7782)
                     /gene="mnmA"
                     /locus_tag="PC494_002162"
     CDS             complement(6703..7782)
                     /gene="mnmA"
                     /locus_tag="PC494_002162"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HDF3912661.1"
                     /translation="MNKKVMIGMSGGVDSSVAAYLLKQQGYDVIGVTMKLWQDDDVVE
                     IEGGCCSLSAVEDARRVANKIGIPFYVLNFREVFKEKVIDYFIDEYLEGKTPNPCIAC
                     NKHIKFDDFYKKARQIGCDYVATGHYAKIEKDESTGRYLLKKSVTDKKDQTYALYNLT
                     QEQLEHTLLPIGDYEKDRVREIAKEMGMAVHNKPDSQEICFVKDNDYANYVKKHSKKR
                     IEEGFFVDTKGNILGKHKGILYYTIGQRKGLGITFGKPMFVIDINPINNTIVLGDNED
                     LFKKELIAKDVNFISIDTLEEPLRVQAKIRYSAKPSPATIHRVGEDTIKIVFDEAQRA
                     ITKGQSVVMYDGDIVVGGGIIEKSL"
     gene            complement(8071..8511)
                     /gene="nifU"
                     /locus_tag="PC494_002163"
     CDS             complement(8071..8511)
                     /gene="nifU"
                     /locus_tag="PC494_002163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly scaffold protein NifU"
                     /protein_id="HDF3912662.1"
                     /translation="MQYSDKVMEHFMNPRNMGEIDNASGVGEVGNPTCGDIMKIFLDI
                     DGDVIKDVKFKTFGCGSAIASSSMATEMIKGKTIKDALELTNKAVAEALDGLPPVKMH
                     CSVLAEQAVKAALIDYAQKNNIHIPELDGYVIDDAHDHDVEEEE"
     gene            complement(8565..9758)
                     /gene="nifS"
                     /locus_tag="PC494_002164"
     CDS             complement(8565..9758)
                     /gene="nifS"
                     /locus_tag="PC494_002164"
                     /EC_number="2.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase NifS"
                     /protein_id="HDF3912663.1"
                     /translation="MEKRRLYMDYSATTPIKKEVLDAMMPYLTDYFGNASSFHTFGRE
                     AKDALDKAREQVAALINAEPSEIYFTAGGSESDNWTLEGVAYANKNKGNHIITSKIEH
                     HAILHTCEYLAKHHGFEITYLDVDSEGKVDLKQLEDSIKDTTILISIMFANNEIGTIQ
                     PIKEISEIAKKHKILFHTDAVQATGNIPVDVKELGIDLMSMSSHKIYGPKGVGALYIR
                     KGVRLHNFVHGGAQEKSKRAGTENIPAIVGYGKAAELAKENMQNHVETLTRLRNKLID
                     GVLERIPYTRVNGSLENRLPGNANFAFQFIEGEGILLLLDMLGIAGSSGSACTSGSLD
                     PSHVLLAIGLPHEIAHGSLRLTVGDFTTDDDIDYILENLPKVIERLRSMSPLYDDAKK
                     QGLVK"
     gene            complement(9776..10222)
                     /locus_tag="PC494_002165"
     CDS             complement(9776..10222)
                     /locus_tag="PC494_002165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HDF3912664.1"
                     /translation="MKLSTKGRYGLKAMFELALNQDNGPVSLKFIAKKQKISDQYLEQ
                     IFSSLKKSGLVKSVRGAQGGYLLSKNAEDITVGDILVVLEGPVALSDCVLDEDVCENS
                     NMCVTKIVWEKMKKGIEDVIDSITLKDMINDYNKNKLENDITNIKK"
     gene            complement(10331..11101)
                     /locus_tag="PC494_002166"
     CDS             complement(10331..11101)
                     /locus_tag="PC494_002166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDF3912665.1"
                     /translation="MIIKLNSTYHSRVMKYLKKEPEYNLFIIGDIERYGYGNNFLNIW
                     ADVGEHGEIKAILLKYFEFMMFYSDGEYDVEGFYNLLRNTNYEEISGKICAVDALAKR
                     LGLNNLKVVDFCKLQTKKFLIDNNCNAKVKRIRLGNLKKTVKLYDLIDEFHSTTLENL
                     KNGLRTGRGYCIEINKQVVSMAKSTSENRTHAMIIGVGTHPKYRAKGLATKCLIKLCS
                     ELLRENKIPCLFYDNEEAGKIYKKLGFENIGKWGIYSK"
     gene            complement(11132..12397)
                     /locus_tag="PC494_002167"
     CDS             complement(11132..12397)
                     /locus_tag="PC494_002167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HDF3912666.1"
                     /translation="MPLADKIRPKTMNDVIGQSHIIGNGKILSKILQSNFLPNMIFFG
                     PPGVGKTTVAEIIAERSNKSFYKINATNSSLEDIKKVISELGSINNVNGVLLYIDEIQ
                     SFNKKQQQSILEFMENGSITLIASTTENPYHYVYKALLSRSTVFEFKPLEKLDIEKGL
                     KRAVEVLNEDSYMDIECNNNAIEDIAILSDGDMRRALNILEVVVYSTKPNKDNITYID
                     SDVIRASTFNKIINYDKNGDSHYDILSAFQKSIRGSDPQASIHYLARLIKGGDLISIC
                     RRLLVIASEDIGLAYPNAIVIVKACVDSAMQLGFPEAKIPLAEATILLATSPKSNSAC
                     IAIMKAMDELDKEFVKDIPNSIKDAHYSGSKEIGRGCGYKYPHNFKNHYVKQQYLPDS
                     IKDSIYYIPQENKTEKNIKKYLEYLNSDF"
     gene            complement(12504..13289)
                     /gene="codY"
                     /locus_tag="PC494_002168"
     CDS             complement(12504..13289)
                     /gene="codY"
                     /locus_tag="PC494_002168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HDF3912667.1"
                     /translation="MASEVLQKTRKINKTLQTSGGSSVSFDLLAGALGDVLSSNVYVV
                     SAKGKVLGLHLNDVQDSSVIEDEYTKQKKFSDEYTQNVLKIDETLENLNGEKILEIFP
                     EEHGRLQKYTTVVPILGSGQRLGTLVLSRYSNSFNDDDLVIAEYSATVVGLEILRAIG
                     EELEEEMRKKAVVQMAIGTLSYSELEAVEHIFAELDGKEGLLVASKIADRVGITRSVI
                     VNALRKFESAGVIESRSLGMKGTHIRILNDKLTDELKKLKNNQ"
     gene            complement(13454..15541)
                     /gene="topA"
                     /locus_tag="PC494_002169"
     CDS             complement(13454..15541)
                     /gene="topA"
                     /locus_tag="PC494_002169"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HDF3912668.1"
                     /translation="MAKTLVIVESPAKAKTIEKFLGKSHYTVKASVGHVRDLPKSKLG
                     VDIENNFEPQYINIRGKGDVIKELKKEAKKSKQVYLATDPDREGEAISWHLAHILNLD
                     ESEDCRIEFNEITKDAIKKAIKHPRNIDINLVDAQQARRVLDRLLGYQISPILWQKVR
                     KGLSAGRVQSVTTKLICDREKEIKAFIPKEYWTIDVEAKTVKDKDITLKFYGKNDEKI
                     ELENEEAVNQILKEMEGKDLKVEKIESKSRRKSAPKPFTTSMLQQEGANKLFFTTKKT
                     MMIAQELYEGIDIEGEGTVGLISYIRTDSKRISDEAKEKAKGYIVNNLGENYYKNTGD
                     KKEKKDTKKVQDAHEAIRPTSVDRTPESIKASLSKDQYKLYNLIWRRFVASQMEDSVF
                     DILNVECKIGDIVFKATGSKMKFDGYTKVYNFSEREDKILPSIEKGDILNIENILPDQ
                     HFTQPPARYTEASLVKTLEELGIGRPSTYAPTIATILNREYVEKQGTSLCPTELGIIV
                     TDILENNFHKFIDVDFTADMESKLDVIEEGNTDWKKIVSESYAPLKEAIEEALENIEK
                     VNMDEETDEICENCGSNMVIKYGRFGKFMACKNYPDCKTTRPIMNKIGVKCPKCEEGD
                     IILRKSKRGKAFYGCSNYPNCDFVAWNKPTGEFCEKCGSYMVEKVTKSETKTVCSNKE
                     CNKETKEHNDGKE"
     gene            complement(15574..16674)
                     /gene="dprA"
                     /locus_tag="PC494_002170"
     CDS             complement(15574..16674)
                     /gene="dprA"
                     /locus_tag="PC494_002170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HDF3912669.1"
                     /translation="MEKRDTYLWLKSIGGITTKTIEIIENEIVNIEDIFDFSEKEIYN
                     LKNISLNIRKNIVKYRGHAYLENIKELLYKKAIKYICKYDKEYPENLKNIYNAPKLLF
                     YKGDIGLVNNNFNIAIVGSRKPTAYGINCAKTISCQLSQYGVNIVSGLAIGIDAYSHI
                     GCMSGKSKTIAVLGSGVDNPLPKQNLHLSNKILENGGLLLSEYNINSTVAPYHFSNRN
                     RIISGLSDGVVVVEAAIKSGALITVDFALEHGKNVFAIPGNINSQMSRGCHKIIKEGA
                     KLIENIDDILNEYNIFNIIDKKINQKYDNISLNAKSKQIIEAIKREGNLHIDSICDYT
                     GIEIKYVNSIINELVLNELVVEMNNKTYSLNV"
     gene            complement(16693..18294)
                     /locus_tag="PC494_002171"
     CDS             complement(16693..18294)
                     /locus_tag="PC494_002171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YifB family Mg chelatase-like AAA ATPase"
                     /protein_id="HDF3912670.1"
                     /translation="MLSIINSSNLVGIDSFLVKVEVDVSNGIPSFNIVGLPGKEIKEA
                     RERVKSAILNSGYKFPSTRIVVNLSPADIKKEGAFLDLSISIGLLRELIKKDENYIRE
                     SMFIGELSLDGKIRKVRGILPIIMGAKTQNIKRIFIPIENIKESLFVDEIDIIPIKSL
                     KECVDFLNEEIKVDKVRIMSFLDDKSRKENEELEKDNSYIDCKYTKINNEESKYDEDF
                     KDVKGNYFVKRSAEIAAAGNHNMFMIGPPGSGKTMIAKRVRTILPDISVEEMIEVSKV
                     YSILGMINETKGIIDKRPFRAPHHTTTKQSLIGGGMDARPGEIALAHRGILFLDEIAE
                     FDRKILETLRQPIEDGYVNISRVKYSAKYPCRVLLVAAMNPCPCGYYMSDTECRCRSN
                     EIDRYINKISGPLLDRFDIFVEVNSIKYSDFNSLKQEESSQKIKRRVENARKIQINRF
                     KKDNIKNNSEIKAYNLFKYCKLEKEASKTAEMIFNKYNLSSRSYTKLLKMARTIADLE
                     ERDLINSQCIIEAFSFRKAYYSYFK"
     gene            complement(18325..18669)
                     /locus_tag="PC494_002172"
     CDS             complement(18325..18669)
                     /locus_tag="PC494_002172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YraN family protein"
                     /protein_id="HDF3912671.1"
                     /translation="MNNKEKGDFGEKVAVNYLLSKGAKILEKNYRLKIGEIDIIAKME
                     DEIIFVEVKSRSNIKFGYPCESVSFKKRKKIIGVASYYIIKNNLNNTPIRFDVIEVYL
                     LEKRINHIMNAF"
     gene            18853..20016
                     /locus_tag="PC494_002173"
     CDS             18853..20016
                     /locus_tag="PC494_002173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HDF3912672.1"
                     /translation="MNREKLVAFIRYLSLFILVVSYLKNVENTLYPVITMIILFLIII
                     NNQVRFFSLSNENTFILISYFLELILIFLLCNYTKTFNSIYFVPLILDISFLIKEKYK
                     YILFSFVIISSLVISLDKNIYLALESSSILLIITVLSIYIENENLSKLYSQNLYDKLR
                     ISKDELKKVNADLETYASSIEELAILKERNRISREIHDSVGHSLSTTIIQLNAIEKLL
                     KDKPLIYDLVHELREFVTESFQDVRRAISELKPVEYENYQSLFKIKELVKSFIKLTNI
                     NVKLTISKNTWNLSRNQSITLYRLIQESLSNSSRHGKATEIRIFITFNTSNLIITISD
                     NGIGCGNIKKGNGLNSINERIYELNGKVEFDNSNNGFTIRASFPKFSGGDFFE"
     gene            20009..20656
                     /locus_tag="PC494_002174"
     CDS             20009..20656
                     /locus_tag="PC494_002174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF3912673.1"
                     /translation="MNKIKVLIVDDEKLIRKGLKIILSSYNDLEIVGDASNGYEALEF
                     CKMNDVDIVLMDIRMKVCDGVLGTRLIKEYNNSITLLILTTFNDDEYIKDAMKFGASG
                     YLLKDSSDEVLHEGIRSSFFGNIVLDKSVAEKIMTSEKTVKQEHLYDMYNLTEKEISI
                     IRLIANGLNNKEISQELFLSEGTIKNNITNILAKLELRDRTQLAIFAFKNKIVIE"
     gene            20785..21720
                     /locus_tag="PC494_002175"
     CDS             20785..21720
                     /locus_tag="PC494_002175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF3912674.1"
                     /translation="MDIVRVNNITKRFNDKLVLDNISFSVKKGEIFGLIGPNGAGKST
                     LINIITNLMLPNSGSIQINGLDLSKDYIKAKSIIGLVPQELAIIETLTSFDNLEYFGA
                     FYGLKGKLLKERIIEALEVTGLTEVKKKKVKKLSGGMQRRLNIGIALLNHPKILILDE
                     PTVGVDPQSRNHIFNFIKDISKKHETTVIYTSHYMEEVEHLCSKIFIMDEGKEIAFGN
                     NDYLKSLVSTNTKLIMEIKNINAQLIFDLKNTKGVISVLENNSLLELDIDKKLQLTDI
                     LSVIDKNNSKIMKISYEEPSLEDVFLNLTGKNLRD"
     gene            21734..22831
                     /locus_tag="PC494_002176"
     CDS             21734..22831
                     /locus_tag="PC494_002176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF3912675.1"
                     /translation="MKLYMSVKTMLKSLKSSFILNLIYFLALPLILSWFLGMVTESMF
                     QNPIKTESTPIVIYDKDNTRLSNDLTKYLKNDLSYILTVKKDDSKAELKLTIPKGYES
                     SLLNEKSNTLNIEKLGTRDDIAILLQDILDTYHEKFYLNNSQKISSEDFSKLFNKNSI
                     DTSIINNNVKQSSYEYFALVSLGFLVIIFIMNNILSNYISESKGLSKRLYSMPITRVQ
                     FLIYDFVGLWIYSFIFLLLYVLFFRILGITFKGNFAILLLLCALSSYFMTSISTFVTS
                     FFSKKYGTAIVYALLFLQTIFGGIFSMISDTFTKLTSLSPTYLIGELFSNYETFKTID
                     SIGDLIFTCLIISTILIALAIVKENYKWREV"
     gene            22834..23898
                     /locus_tag="PC494_002177"
     CDS             22834..23898
                     /locus_tag="PC494_002177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF3912676.1"
                     /translation="MIRLTIANIKRYLKNHTLLINMVMLPIILIFSLNFFINNSGNQS
                     MYFSPVAIVSDSSGKYEHKLINSSKLKENSFRLNEQDKAMNLLKNNKVSAVFVLDKNF
                     SNSIDKLQRPVVKCFKIENGGGSLWAESQIESFITKSLKLKVDKNIDDKLTKTNIIDN
                     KPDKNKGSFLVVFLICYFMYINAAHLASDLFTLKKSNVLKRLISTDNKDIKIIFSIFL
                     GLFFIQSIVYTFALLCFSIIEDFNLSLNVLMIVLANSFVSTGFVFWVARVFKNESSIS
                     LISTFYSLIGLAISISSLIPSMDKLSFMTNLSKFTPFYWTIDAIKNNGSILINIIALI
                     LIGIIFVTAGSLKLRDFAKN"
     gene            24142..24639
                     /locus_tag="PC494_002178"
     CDS             24142..24639
                     /locus_tag="PC494_002178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CarD family transcriptional regulator"
                     /protein_id="HDF3912677.1"
                     /translation="MYKIGESVMYPKEGACSVNDIVTKKINHEMQKYYELSVIFNSNL
                     KISIPVLNADRIGIRPVMDGNDVDNFIQSINKTDGVWIFDRKERLKLYQDKFHSGDVF
                     EIVKLIKMLMIQDSSKQLCSTDKEFLNKAQKFALSELAAAQCKSYTMVLEEMKKHILN
                     SKNIN"
     gene            complement(24816..25064)
                     /locus_tag="PC494_002179"
     CDS             complement(24816..25064)
                     /locus_tag="PC494_002179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3912678.1"
                     /translation="MSRKAYEEALVELEKFIDERKEIIKSAEDCIDKYIVDRTLPFDY
                     KDKCVEWQQELLDIAEAQVLEANELSVLLQEKKELEED"
     gene            complement(25130..26146)
                     /locus_tag="PC494_002180"
     CDS             complement(25130..26146)
                     /locus_tag="PC494_002180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HDF3912679.1"
                     /translation="MEYNELLKSARENLNGSCKVCKVCNGVACAGEVPGMGGKGSGSS
                     FIENSKSLEKVKVNMRVIHDVSNPDTSIEMFGKKMSAPIFAAPVTGTTLNMGGKINER
                     DYIEPVVAGCANSGIYAMVGDTAVDAFLMENLDVVKKYNGAGIVFIKPWDNENIIKKI
                     RLAEEAGAFAVGVDIDACGLVTLSLHGKPVLPKNVKQIKELVKSTKLPFILKGIMTVE
                     DALMAVEAGVDAIVVSNHGGRVLDCTPGACEVLPKIADAVKGKVTILADGGVRTGLDV
                     LKMIGLGADAVLIGRPFVTASFGGATDGVETYVNKLQSELSSSMILTGCQTIKDIDGK
                     VIYK"
     gene            complement(26204..26971)
                     /locus_tag="PC494_002181"
     CDS             complement(26204..26971)
                     /locus_tag="PC494_002181"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HDF3912680.1"
                     /translation="MQDKSVREIKEIIETLEVEKYMEYIELLRVDERKSVQGLAIKLA
                     KKLDNIRKEEERLETINIFENEGYDKGYLYIGGIDEAGRGPLAGPVVASVVVFKKDTK
                     IEGVNDSKKLSEAKRDELFEVIKEEALDYGIGIVNNEEIDEFNILNATYMAMKKAINC
                     LKKAPDYLLVDAATIPGIDISQNPIVKGDSKSISIAAASILAKVTRDSIMYQYDRVYP
                     EYGFKSHKGYGTKEHYEAIEKYGITPIHRKSFLKNIL"
     gene            complement(27039..29228)
                     /locus_tag="PC494_002182"
     CDS             complement(27039..29228)
                     /locus_tag="PC494_002182"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosylcobalamin-dependent
                     ribonucleoside-diphosphate reductase"
                     /protein_id="HDF3912681.1"
                     /translation="MKYIIKRDGTKELFSKSKIEDAVYKASINSEGGVDRELAYDISR
                     KIANDYNSMEKCLSVEEIQDIVEVLLMESNRKDIAKHYILYRERRSEIRTKAWEFDEL
                     QKSIWKNKYRHNGESFDEWIKRISNNSSRISKLIRQKRFLFAGRILANRGLQKEGKKV
                     TYSNCYVIEPPKDSIEDIFDTAKKLARTFSYGGGVGIDISKLRPKGAKVNNAAKHTTG
                     AVSFMELYSMTTGLIGQRGRRGALMISMDVNHPEIEDFIDIKTDLEKVTKANISVRVT
                     DEFMQAVREKKLYNCTFEVETTGEKIVKIVNAYDLFNKFVKNNWDYAEPGILFWDKIK
                     TYNFMSEDKNFCFSGVNPCAEEPLPSGGSCLLGSINLSEFIIQPFGEHATFDINKLKS
                     CVREAVVALNDVLDEGLNLHPLQEQRDSVHKYRQIGLGVMGIADMLIKMGIRYGSDES
                     LELCDLIGKTMLNEAVKQSALIAKEYGTFSEYKYENISKSKFFIENLNEDTKEMVKKY
                     GLRNSQLLTIPPTGSISTMIGISGGIEPIFNLSYIRKTESLHDEDVYYKVYTPIVKEY
                     MDKKGITDEECLPDFFVTAMNIGYEERINMQKVWQKYIDASISSTINIPFETTVEDVF
                     NIYIKAWEAGLKGVTIFRDGCKRSGILINEKKEENNKEDKKENSKKEYYKNNKKEKDN
                     KDEKAKEIINKNFEEDEKFVCPECGSEGIAHTGGCSICLKCGYSGCN"
BASE COUNT         9283 a         5158 c         3128 g        11788 t
ORIGIN      
        1 agatatatta ttcaccaaaa ttcataaatt ttttggtatt tttaataaaa aacaaaaaaa
       61 cagatatata ctataaatgc ttttacaatt aataaggttt aattaaagca aatataataa
      121 atatctgatt tttatataca aacttaatta cttatctagt taagtccatt tgattcatct
      181 tcgtcgtaat ttaaaccttc ttcttccatt atagcagtat acacagctac aacagtttca
      241 tactcttcat cactttccaa aggtattaag atttcacctt cttcatcctc atcaattcta
      301 aagattaaag cttcttcagc ttcttcatca tctaaaggca ttaatattgc atactctttt
      361 ccttctgctt ctaatgttaa tattatttca aattggcttt caacgccatt ttcgtctatt
      421 aaatttatta tattttcttc cataatgtca ttcacctcaa atttattttt atttttatta
      481 tttatattat atatcataag tattcaattt tatagttctt ttatgaattt attttaaaat
      541 ctaaatatcc ttgcaaaatt attactgctg ccaacatatc tataaccttt tttctttttt
      601 gtctactaac atctgcttct aataaagacc tctctgccgc tactgtagaa agcctctcat
      661 cccaaaactc tacatcaata cctgtttctg cttttaccaa ttcacaaaac ttgattactt
      721 tttctccttg tggacctaaa gttccattca tattttttgg taatcctgat acaattttat
      781 ttacttgttt ttcttttatt attgctttta gctcttcaat atcttttttc ttgccaactc
      841 tttttattgt ttttacacct tgtgcagtta atcccatcaa atcactcaca gcaactccaa
      901 tagttttatc accaacatca agacccatta ttcttccatc taacatagtt cctcctttat
      961 ctatttatat tctatagatt aaatacatat tctgaacctc tcataactaa ggtcacaggc
     1021 ttactgcttc atataatttt acataatcaa tcataaaaat tgcaatatga ttttttatgt
     1081 aagcatccag tttacattaa taatcatatt gcatttttta tttaaatcct atatgaacag
     1141 taaaaatttt tttagttatt tttttcaaat attatcatat ttatacttat tattattagt
     1201 ggtataagta tatatataga tgctgtagat gcagcaacta ttccagaatc attaactaaa
     1261 agagtaatta tacaaccaac catagatgca ataaaccctt taaacaagat tggaaaatta
     1321 ttcattatct ttctaaagtg tctagatggt ttaaatataa gcactgcaat tactccaatt
     1381 cctacaagta aaatatttac ccatacactt gtctgtgcta gttgcatatt catttgaatt
     1441 tttcttccaa atgtttgtaa tatctctcct ggtccattta ggaaaattct ctgtacaaac
     1501 atacctaaat gagattcact acctgaaagt atatctaaag ctgcaaatgc aaaaacgaca
     1561 actacagctg aaacagctaa taatacagct ttcttaaaat ctattttaat gtcatatata
     1621 agcattataa acaacaaata tgctacacat tctgatatag ctccaccaac atttgcaccc
     1681 attgaaggat atgcactagt tataagtatt attaatgaaa aaattacaac aagtaattta
     1741 gataccttct tataatgtaa taatactgct aagccaaata ctgcacttgc tatagttaca
     1801 ccttcatatt catttcctac accatagtac ctagctccta tgacagcatc ataactcatt
     1861 atgttatttt gcattaagta tgttccaaat acagaatcta taactatgac taaaatagta
     1921 agtgttgcaa aaaatcccat gtgctttata tcattgtcct taaataattt tctacctaac
     1981 aagtataata ttagcgtagt cgcaaatatt cccaaagata ttgaaattgg agttttaaaa
     2041 ttcatcaaag gagctaacat aaatgatagt ggcattatta tgcctaattt tataaactcc
     2101 ttaagtactt tgaatacacg ctctttatgt ggcatataat ttctaaagaa aatcgcaaac
     2161 atggcaatta cccaagaagc agatattacg cctacaaagc catttataat agttgacctt
     2221 attgaagata tagacactat cctttcataa agtgatttta gatagctaat attgtcctct
     2281 ttatttacta aagtataact tctacctacc atctctttat tttcaagacc aaatgtacct
     2341 agtatatcta ctccaacatc taaattggca acaattccag cctttcttgt tgtggcagat
     2401 tccagtagac ctttcccttc tccactaaat tttattattg gagaaagtct tctcttattc
     2461 ttataatcta ggtcacttgg aaatgcactt gctatataaa cagtgtcatt ttctccaacc
     2521 atagaaaata cttgttcaag atatttattt atatttttta caatattttt cttcattgta
     2581 tcataagtat tatcatttag atttaatcta tacatatcta atctatatgt atctccaagt
     2641 tctacaaata tagcatcact atttttatag gattttttag tttcatctag taatttatca
     2701 taatctgtag atattccaaa tggcatttta gaatctttct tattaatatt atcaatatta
     2761 cctgaatcaa tccttccata ttggtccata gctactaaac ataagtttct gtttttaact
     2821 aattgattat tttcaattat atcagcattt ccaattacag atgtctttaa accattttct
     2881 gataaagttt ttcctaatga ccctaaattt gctccatatt ctccatactc aagattttca
     2941 tttatagatc tattaatgcc taaatcattt atttctttag ctttttgacc tgttgcgact
     3001 tcaaaagctt tagcagtatc ttggtctact ttttgaaaat tgatatagtc ttcagtagtt
     3061 acactagctc ttgttcctgc acccatactt gcataagacc ttctatcatc agtaccttga
     3121 tcccctctta tattcatgag agctacatag cctctctttt ctatctcatt tttcaagatt
     3181 ggaatattca tcatacttcc aagattggtc ctattcatat caataaatat gaccttgcct
     3241 ttttcttcag caaaaccata gctagcagtt gatacaaaaa tcataatgac tattgcaaac
     3301 aacgacataa tcttttttct catttatttg acctactttc tattcagata gtgcgtgatt
     3361 acttcttcaa gtatctcatc tctttcaaat tttttaatta tagctcttgc atttttatga
     3421 ctagttatat agctagaatc accagaaagg agatacccta taatttgatt tatagggtta
     3481 tatccttttt caactaatgc tttatataca aaatcaatag tatctcctac actcatccta
     3541 tcttctggta ttccttcaaa tttcatagtg tagtctaaat ctttttccaa actaaaaacc
     3601 tccttgagtg aatgttattt aacttgtgtc ttaataacct cacttgcata gcttaaagct
     3661 tggtcaacct tagatacatc actagctcct gcttgtgcca tattaggtct tcctccacct
     3721 tttcctccag ctatttttgc aacttctcta acaatattac ctgaatgtat tcccttatct
     3781 aatacatctt tagtggcagt aactacaaag ttaactttat catctactac atttgcaagt
     3841 actactacac cagaaccaag cttatctctt agattatctg ctgtttctct tagtgtatcc
     3901 atatccatac cttcaaattt attagttatc aaattaactc catttacttc aactttagaa
     3961 tcaaaaatag aatcaactga ttgtaaactc atcttagctt tcatatcatg caattcttta
     4021 gataagtttt tattttcttc taataaagaa cttattcttt gaattaaatt atcttcttta
     4081 gattttaagt ttacacaaac ttcagagata attccatctc tttcttttag gtattcataa
     4141 acagcttttc ctgttattgc ttctattctt cttacacctg ctgctactcc accttcagat
     4201 aatattttga acattcctac ttgagaagta tttgtcaagt gagttcctcc acaaagttct
     4261 gtagaataat ctcccataga aactactctt acctcatcac catatttttc accaaatagt
     4321 gctgtagctc ctttttcttt agcttccttt atattcataa tatcacattt tatgtctaaa
     4381 gatgataaaa taacattatt tactttttct tctattactt ttaattcttc atttgatatc
     4441 gcttcaaagt gagtaatatc aaatctaagt ctttctggag ttactaaaga accagcttga
     4501 ttaacatgtt ctcctaatac ttctcttaat gccttatgaa gtaaatgtgt agcactgtga
     4561 tttcttgcag ctgacattct agtttctcta tctacgagtg tctttacttt gtccccatta
     4621 cttattcttc ctgattttat tatacctata tgttttatac tattattagc acctttttta
     4681 gtatttaata cttctaaaac taagttttca ttagttatca atccacaatc tccaacttgt
     4741 cctccacctt caggatagaa agtagtgtta tctagtacta tagatacctt atcgccttct
     4801 tctgcacttt gaactagctc atcatcttta actatagctt caatagttcc ttcaccataa
     4861 atttcactat acccattaaa tgtactgtca actgtagatt ctaattttga tagagggtct
     4921 tccttccaac tttctctatc catatttcct ctagcatttc tagctctttc tttttgcttt
     4981 tccatttctt cattaaaagc ttcttcatct acagatagat gttcttcttc taatatttct
     5041 ttagttaagt ctatagggaa gccataagta tcatatagtt taaaagcttc ttgaccactt
     5101 aggacagtct ttccttcatt ttttaatact tctatataag agttcaatat ttctgttcct
     5161 tggtctatag tttcattgaa tttttcttct tctattccaa ctactttttt aatataactt
     5221 tctttttcaa ctaaaactgg atatgcttta tcatttactt ttataacttc atctattagt
     5281 ttctgtaaaa ataattcttt tactcctaat aacttaccat gacgagcagc acgtctaagg
     5341 agtcttctaa gaacatatcc tcttccttca tttgatggaa gcactccatc actaactaag
     5401 aatgttacag ctcttatgtg gtcagttatt attcttattg atatatcatt ttttggattc
     5461 tctccatatt ttactcctgt taacttctca actgcttcta gtatagattt aattgtatca
     5521 acttcaaaga tagtgtctac gccttgcata atacatccca ttctttcaag acccatacct
     5581 gtatctatat tcttgttttc taatagacta taatttcctt cttcatctct atcaaattga
     5641 gtaaatacat ggttccaaaa ttctaaatac ctatcacaat cacagcctgg tttacagtct
     5701 ggattgtcac atccatattc ttctcctcta tcaaaatata tttctgaaca aggaccacaa
     5761 ggacctgtac ctatttccca gaaattatca tcttttccaa gtctaaccat tctttcttct
     5821 gggaaattca tttcttttgc ccatatatca taagaatcat catcttcttc atatacagtc
     5881 acccatatct tatcttctgg tatatttagc cattctgtaa caaattccca tccccatttg
     5941 attgactctc ttttaaagta atctccaaat gagaagttac ccatcatttc aaagaatgta
     6001 gcatgtcttg cagttatacc tacattttct atatctcctg ttcttataca tttttgagat
     6061 gtacacattc tcacacttgg aggtacttct acacctgaaa agtagttttt caaaggtgcc
     6121 atacctgagt ttataagtaa caaactctta tcattgtttg gtactaaaga ataactattt
     6181 gctacataat gaccttttga ctcaaaaaat tctaaaaact tacttcttat ttcatttaat
     6241 cccatctttt ccatatcatg ttcctcctaa taaattttat tttttcgttt aaataaaaaa
     6301 cctcgtccct ataaataaat ttataggggc gaggacaatc gcggtaccac cctaattatc
     6361 atacaaagta tgatatcttc ggaaaacctt agctataacg taactaccgt caatctctac
     6421 ttaaatcttc tttataaaat ataaattgtt caagattgct actaaaaggc tgcttcaaat
     6481 atcatattct aagggcttcc agcatttccc tctctctgta agacatcaaa tattttacta
     6541 ttccttatca ctgtatttgt tttttaatta atatactaat tatattacta aattttacaa
     6601 aattaatcaa tactatattt tcatatacaa taaatttatt ttataaactt tatttactct
     6661 taatatactt tattgcttat ttttttaatt ttttagatgt ttttataaac ttttctcgat
     6721 tatacctcca cctactacaa tatctccatc atacattact acagattgac ctttagtaat
     6781 agctctttga gcttcatcaa aaactatttt aatagtatct tctcctactc tatgaatagt
     6841 agctggtgat ggttttgctg aatatcttat tttggcttga actcttaagg gttcttctaa
     6901 cgtatctatt gatataaagt taacatcttt agcaataagt tcctttttaa ataaatcttc
     6961 attgtctcca agaactatgg tattatttat tggatttatg tctattacaa acattggttt
     7021 tccaaaagta attccaagcc cttttctttg gcctatagta taatataata tacccttatg
     7081 ttttccaagt atattgcctt tagtatctac aaaaaaacct tcttcaatac gctttttaga
     7141 atgttttttt acataatttg catagtcatt atctttaaca aaacaaattt cttgactatc
     7201 aggcttattg tgtactgcca tacccatttc cttagcaatt tctcttactc tatctttttc
     7261 atagtcacct attggtagta aagtatgctc tagttgctct tgtgtaagat tataaagtgc
     7321 ataagtttgg tcttttttat ctgtaacaga tttttttagc aaatatcttc ctgtactttc
     7381 atccttttct atctttgcat agtgacctgt agctacataa tcacaaccta tttgtctagc
     7441 cttcttataa aaatcatcaa attttatatg tttattacaa gctatacagg gattaggagt
     7501 ttttccttcc aaatattcat ctataaaata atctattact ttttctttaa acacttctct
     7561 aaaatttaaa acataaaatg gtatacctat tttatttgct acccttctag catcttcaac
     7621 agcagataaa gaacaacaac caccttcaat ttcaacaaca tcatcatctt gccacaactt
     7681 catagtaaca ccaatgacat catatccttg ttgttttaaa agatatgcag ctacagagct
     7741 atcaactcct ccactcatac ctatcattac ttttttattc ataaacaaat ttcacctcat
     7801 cttttgcatt acttattatt ataccatata gagcaagtat tgtacttatt taaaatatag
     7861 cttgttctat tttctaaaaa aataatcatc tttattattt gaatcttatg gattattttg
     7921 ttaactaatt aacctctaaa tcaagttaaa atacttaatt taggcaataa aaaatagcca
     7981 ttttaaaaac agctattttt tatgtcctaa ttatatcatt agtacttctt tttaatcatt
     8041 gtaaacttct cataacacaa tcacttattt ttattcttct tcttcaacat catggtcatg
     8101 agcatcatct ataacatatc catccaattc tggtatatgg atattgttct tttgagcata
     8161 atctataaga gctgctttta cagcttgttc agctaaaact gaacaatgca tctttactgg
     8221 tggtaaacca tccaaagctt ctgcaacagc tttatttgta agttctaatg catcttttat
     8281 agtttttcct tttatcattt cagttgccat agaagaactt gctatagctg aaccacagcc
     8341 aaatgtttta aacttaacat cctttattac atctccatct atgtctaaaa atatcttcat
     8401 tatatctcca catgtagggt ttccaacttc acctacacca cttgcattat caatttctcc
     8461 catatttctt ggattcataa aatgttccat aactttatca ctatattgca ttatcttttc
     8521 ctcctactca atttatgtct attttttatg ctttatcttt atgtctattt tactaaacct
     8581 tgtttcttcg catcatcata aagtggtgac atgcttctaa gtctttctat tacttttggt
     8641 aagttctcta gtatataatc tatatcatca tctgttgtaa aatctccaac tgtaagtctt
     8701 aatgaaccat gtgctatttc atgtggtaaa cctattgcaa gaagtacatg tgaagggtct
     8761 aatgaaccag aagtacatgc agaaccactt gaaccagcaa ttcctaacat atctaataat
     8821 aaaagtattc cttcaccttc tataaattgg aatgcaaagt ttgcatttcc tggcaatcta
     8881 ttttctaagc taccatttac tcttgtgtaa ggtattcttt ctaacacacc atctattaac
     8941 ttatttctaa gacgagttaa agtttctaca tgattttgca tattttcctt agctaattct
     9001 gctgcttttc catatccaac tattgcaggt atattttctg taccagctct tttgcttttt
     9061 tcttgtgctc caccatggac aaagttatga agtcttacac cttttcttat gtataaagct
     9121 cctacacctt ttggtccata tattttatgt gaagacatac tcatcaaatc tattcctaat
     9181 tctttaacat ctactggaat attacctgta gcttgtactg catcagtgtg gaataatatc
     9241 ttatgttttt tagctatttc ggatatttct ttaataggct gtatagttcc tatttcatta
     9301 tttgcaaaca ttatacttat aagtatagta gtatctttta ttgaatcttc tagttgcttt
     9361 aagtctactt ttccttcgct atcaacatct aaataagtta tttcaaatcc atgatgtttt
     9421 gctaagtatt cacatgtatg aagtattgca tggtgttcta tttttgaagt tattatatga
     9481 ttacctttgt ttttattagc ataagctaca ccctctagtg tccagttatc actttctgaa
     9541 ccacctgctg taaaatatat ttcactaggt tcagcattta taagggctgc tacttgttct
     9601 cttgctttat ccaaagcatc ttttgcttct cttccgaatg tgtgaaaact agatgcatta
     9661 ccaaaataat ctgttaggta tggcatcatt gcatccaata cttctttttt aataggtgtt
     9721 gttgcagaat aatccatata caatcttctt ttttccatta cattcatctc caaatctatt
     9781 ttttaatatt tgttatatca ttttctaatt tatttttgtt atagtcattt atcatatctt
     9841 taagagtaat tgaatctata acatcttcta tacccttttt catcttttcc caaactattt
     9901 ttgttacaca catgtttgag ttttcacata catcttcatc tagtacacag tcagataatg
     9961 caactggtcc ttctaatact acaagtatat ctcctactgt tatgtcttca gcattctttg
    10021 aaagcaaata acctccttga gcacctctca cactttttac tagacccgat ttttttaaag
    10081 atgaaaatat ttgttctaag tactgatctg atattttttg cttcttagca ataaatttta
    10141 atgatactgg tccattgtct tgatttaatg ctaattcaaa cattgctttt agtccatatc
    10201 tacctttagt agacaacttc atatattatc acctctatat agaaatctaa ttcatactgt
    10261 tttagtagga attactttca agataatttt attataccct actaattttg tcaagattaa
    10321 ttttaatttt ttattttgaa taaattcccc attttccaat gttttcaaat cctagttttt
    10381 tatatatctt tccagcctct tcattatcat aaaacaaaca aggaattttg ttttctctca
    10441 gtaactctga acatagttta attaggcatt ttgtagcaag tcctttagct ctatatttag
    10501 gatgtgttcc tactccaatt atcattgcat gagtcctatt ttctgaagta ctctttgcca
    10561 ttgacaccac ctgtttgtta atctctatac aatatcctct acctgtcctt agtccatttt
    10621 ttaaattctc taaagttgta ctgtgaaatt catctattaa gtcataaagt tttactgtct
    10681 tttttagatt tccaagccta attctcttaa cctttgcatt acaattatta tctatcaaaa
    10741 actttttagt ttgaagtttg caaaaatcaa ctacctttaa attattaagt cctaatctct
    10801 ttgctaaagc atctacagca catattttcc cagatatttc ttcgtaatta gtattacgaa
    10861 gtagattata aaaaccttca acatcatact ctccatcaga ataaaacatc ataaattcaa
    10921 aatatttaag taatattgcc tttatttcac catgttcacc cacatctgcc catatattta
    10981 aaaaattatt tccatatcca tatctttcaa tatcccctat tataaacaaa ttgtactcag
    11041 gttctttttt taagtatttc ataactctac tgtgataagt tgagttaagt tttataatca
    11101 taatatctac ccccgataca taaagttcag tctaaaaatc actatttaga tattctaaat
    11161 atttttttat atttttctca gttttatttt cttgtggtat gtaataaata ctatctttta
    11221 tgctatctgg taaatactgt tgctttacat aatgattttt aaaattatga ggatatttgt
    11281 atccacaacc cctacctatt tctttagaac cagaatagtg agcatccttt atactatttg
    11341 gtatatcctt aacaaactct ttatccagtt catccatagc tttcattatt gctatacatg
    11401 cagaattaga ctttggagat gtagccaaaa gaatagtagc ttctgctaat ggtattttcg
    11461 cttctggaaa tccaagttgc atagctgagt ctacacatgc ctttacaatt acaatagcat
    11521 ttggataagc taaacctata tcttcactag ctattactaa aagtctccta catatactta
    11581 tcaaatcccc accttttata agtcttgcta gatagtgtat agatgcctgt gggtcacttc
    11641 ctcttataga tttttgaaat gcacttaaaa tatcataatg actatcacca tttttgtcat
    11701 agtttataat tttattaaat gtagatgccc ttattacatc tgaatctata taagttatat
    11761 tatccttatt tggtttagtt gaatagacta ccacttctaa aatatttaag gctcttctca
    11821 tatctccatc agaaagaatt gctatatctt caatagcatt attattgcac tcaatatcca
    11881 tatagctatc ttcatttaat acttcaacag ctcttttcag tcctttttct atatcaagtt
    11941 tttctaaagg tttaaattca aatacagtag acctacttaa aagagcttta tatacataat
    12001 gatatggatt ttctgtagtg ctagcaatca aagttatact cccattttcc ataaattcta
    12061 atattgattg ttgctgtttt ttattaaaac tttgtatttc atctatatat aataggactc
    12121 catttacatt atttatactt ccaagctctg atatcacctt ttttatatct tctaaagatg
    12181 aattagtagc atttatttta tagaagcttt tattgcttct ttctgctatt atttccgcta
    12241 ctgtagtttt accaacacca ggaggaccaa aaaatatcat atttggtaaa aaattagatt
    12301 gtaatatctt agacaatatt tttccattac ctattatatg actttgacct attacatcat
    12361 tcattgtttt tggtcttatt ttatctgcta aaggcatttt ctcactcctt tttaatatac
    12421 ttatcattac cttaataatt cgtctaaaaa aggtatctat ttgaaataga taccttttct
    12481 aatctaaacc tataaaatat agattattga ttgtttttta atttttttaa ttcatctgta
    12541 agtttgtcat taagtattct tatatgagta cctttcatac ctaatgatct tgattctatc
    12601 acacctgcac tctcaaattt tctaagtgca tttactatta cagacctagt tataccaact
    12661 ctatcagcta tcttacttgc tacaagtaga ccttcttttc catccaattc agcaaaaata
    12721 tgttcaactg cttcaagctc ggagtaggac agagtgccta ttgccatttg aactacagct
    12781 ttctttctca tttcttcttc taattcttca cctattgctc ttaatatttc aagaccaaca
    12841 acagttgcac tgtattcagc tattactaaa tcatcatcat tgaatgaatt tgaatatctt
    12901 gaaagtacca atgttcctaa tctttgaccg cttcctaata ttggaactac tgtagtatat
    12961 ttttgtaatc ttccatgttc ttcaggaaag atttctaata tcttctcacc atttaaattt
    13021 tctaatgttt catcaatttt taacacattt tgagtatatt catctgaaaa tttcttttgc
    13081 ttagtatact catcttctat aactgaactg tcttgaacat catttaaatg aagacctagt
    13141 actttacctt ttgcacttac tacataaaca ttagaactta aaacgtcgcc caatgctccg
    13201 gccagtaaat caaaagagac actgcttcca ccacttgttt gtaatgtttt atttattttc
    13261 cttgtttttt gtaacacttc acttgccatt taatcatctc ctcatgaaat ttaggccttt
    13321 taataacctt ttatattttc taatattatt ttcacattta atgaaaattt atttttctat
    13381 tagttgttta cacttgaaag attatcatag attggaacct ttttcaagag aattatgtga
    13441 tttttttcaa ttttcactct tttccgtcat tatgctcttt tgtctcttta ttacattctt
    13501 tattagaaca cactgttttt gtttcagatt tagtcacttt ttcaaccata tatgaaccac
    13561 acttctcaca aaactctcct gttggcttat tccaagctac aaagtcacag tttggataat
    13621 tagaacaccc ataaaaagct ttacctcttt tagattttct aagtataata tctccttctt
    13681 cacattttgg acatttaaca ccaattttat tcataattgg tctagttgtt ttacaatcgg
    13741 gatagttttt acaagccata aactttccaa atctaccata tttgataacc atattagacc
    13801 cacagttctc gcaaatctca tcagtttctt catccatatt tactttttct atattttcaa
    13861 gagcttcttc aatagcctct ttaagtggtg catatgattc tgatacaatc tttttccagt
    13921 ctgtattgcc ttcttctata acatcaagtt tactttccat atcagcagta aaatctacat
    13981 ctataaattt atggaaatta ttttccaaaa tatcagtaac tattattcca agttctgttg
    14041 gacatagact tgttccttgc ttttcaacat actctctatt cagtatagta gctattgttg
    14101 gagcatacgt acttggtcta cctataccta gttcttctag tgtttttact aaactagctt
    14161 ctgtatatct tgctggtggt tgtgtaaaat gttggtctgg caatatattt tctatattta
    14221 atatatctcc tttttctata cttggtaaaa ttttgtcttc tctttctgaa aaattatata
    14281 ccttggtata accatcaaat ttcatttttg aaccagttgc cttaaataca atatcgccta
    14341 ttttacattc tacatttagt atatcaaaca ctgaatcttc catttgacta gctacaaatc
    14401 ttctccaaat taaattgtat aacttgtact ggtctttgct caatgaggct tttatactct
    14461 caggagttct atcaactgag gttggtctta ttgcctcatg ggcatcttga acctttttag
    14521 tatccttttt ttctttttta tcaccagtgt ttttatagta gttttctcct aaattgttta
    14581 cgatatagcc cttagctttt tcttttgctt catcagatat tcttttagag tcagttctta
    14641 tatatgatat aagaccaaca gtaccttcac cttctatgtc gataccttca tataattctt
    14701 gtgctatcat cattgttttt ttagtagtaa aaaataactt atttgctcct tcttgttgaa
    14761 gcatacttgt tgtaaatggt tttggagctg atttacgtct tgatttagat tctatcttct
    14821 caacctttaa atctttacct tccatttctt ttagtatttg atttacagct tcttcatttt
    14881 ctaattcaat cttttcatca tttttaccat aaaatttcaa agttatatct ttgtctttta
    14941 cggtcttagc ctcaacatct attgtccagt attcttttgg aataaatgcc tttatttctt
    15001 tttctctgtc acaaattaac tttgttgtaa cagattgcac tctacctgca ctaagacctt
    15061 ttctaacctt ttgccataat ataggactta tttgataacc taaaagtctg tctagcactc
    15121 ttcttgcctg ttgtgcatca accaaattta tatcaatatt tctaggatgt ttaattgctt
    15181 ttttaattgc atccttagtt atctcattaa actctattct acaatcctca gattcatcta
    15241 aatttagtat atgagctaaa tgccatgata tagcttcacc ttctctatca gggtcagttg
    15301 ctagatatac ttgtttagat tttttagctt ctttttttaa ttcttttatt acatcgcctt
    15361 ttcctcttat atttatatat tgaggttcaa aattattttc tatatctaca cctaatttac
    15421 ttttaggtaa atctctgaca tgaccaactg atgctttaac tgtgtaatga cttttcccta
    15481 aaaatttttc tatagtttta gcttttgcag gcgattctac gatgactaat gttttggcca
    15541 taaaaccata cacccccact acctaatctt aatttataca tttaaactgt acgttttatt
    15601 attcatttct actactaact catttagtac taattcattg attattgaat ttacatactt
    15661 tatttctata ccagtataat cacaaatact atctatatgc aagtttcctt ctctttttat
    15721 agcttcaatt atttgcttag acttggcatt tagacttata ttatcatatt tttgatttat
    15781 ttttttatca ataatattaa atatgttata ttcatttaaa atatcatcta tattttcaat
    15841 taattttgca ccttctttta taattttatg acaacctcta ctcatttgag aatttatatt
    15901 accaggtatt gcaaaaacat tttttccatg ttcaagagca aaatctactg tgattagtgc
    15961 accacttttt attgctgctt ctacaacaac tactccatca cttaaaccac tgataattct
    16021 atttctatta gaaaaatggt acggggctac tgtcgagtta atattatact ctgataataa
    16081 taatccccca ttttctaata ttttatttga taaatgtaaa ttttgttttg gaagaggatt
    16141 gtctactcct gaaccaagta ctgctatagt tttagatttt ccactcatac aacctatgtg
    16201 cgagtatgca tctattccta tagctaatcc acttactata ttaactccat attgggatag
    16261 ttgacaactt attgtttttg cacaattaat tccataggct gtaggttttc ttgaacctac
    16321 tatagctata ttaaaattat tattaactaa gcctatgtca cctttgtaga ataataactt
    16381 tggagcgttg tatatattct ttaaattttc aggatattct ttatcatatt tacaaatata
    16441 tttaatcgct tttttgtaaa gtagttcttt tatattttct aaataagcgt gacctctata
    16501 ttttactata ttttttctaa tattcaagct tatatttttt aaattatata tttctttttc
    16561 agaaaaatca aatatatctt caatatttac tatttcattt tctattattt caattgtttt
    16621 tgttgttatt ccaccaattg attttaacca taaataagta tctctttttt ccataaaatc
    16681 cacctcaaaa aactatttaa aataactata ataagccttt ctaaatgaaa aagcttctat
    16741 aatacactgt gaatttatca agtctctttc ttctaaatct gctattgttc ttgccatttt
    16801 taaaagtttt gtataacttc tactgcttag gttgtattta ttaaatatca tctcagccgt
    16861 ttttgaagct tctttttcca gtttacaata tttaaataaa ttgtaagctt taatttcact
    16921 attatttttt atattatcct tcttaaatct atttatctgt atttttctag cattttctac
    16981 tcttctcttt attttttgag agctttcttc ttgttttaaa gaattaaaat ctgaatattt
    17041 tatagaatta acttctacaa aaatatcaaa cctatctaac aatggacctg atattttatt
    17101 tatgtatcta tcaatttcat tacttctaca tctacactct gtgtctgaca tataataacc
    17161 acatggacat ggattcatag ctgcaactaa cagtactcta caaggatatt ttgcactgta
    17221 ctttactctg gatatattta catatccatc ttctataggt tgtcttaaag tctcaagtat
    17281 ttttctatca aattcggcta tctcatctaa aaataagata cctctatgtg ctaaagcaat
    17341 ttctccaggt cttgcatcca ttcctcctcc aattaaagat tgctttgtag ttgtatgatg
    17401 aggtgctcta aaaggtcttt tatcaattat tcctttagtt tcatttatca tacccaatat
    17461 actatagacc ttacttactt ctatcatttc ttctacactt atatctggta aaattgtcct
    17521 tactcttttt gcaatcatag tttttcctga gcctggaggt ccaatcataa acatattatg
    17581 atttccagca gcagcaattt ctgcactcct ctttacaaaa taatttcctt ttacatcttt
    17641 aaagtcttca tcatatttac tttcttcatt attaatctta gtatatttgc aatctatata
    17701 actattatct ttttctaatt cttcgttctc ttttcttgac ttatcatcca aaaaagacat
    17761 tatccttact ttatcgactt ttatctcttc gtttaaaaaa tcgacacatt cttttaaact
    17821 tttaatagga attatatcaa tttcatctac aaatagactt tcttttatgt tctcaattgg
    17881 tataaaaata cgttttatgt tctgagtttt tgcacccata attatgggca atatacctct
    17941 tacttttctt attttcccat ctaatgataa ttctcctata aacatacttt ctcttatgta
    18001 attttcatct ttttttatta actctcttaa aaggcctata cttatagata aatctaaaaa
    18061 agctccttct ttttttatat ctgctggtga taaatttaca actattctcg tgcttggaaa
    18121 tttatatcca ctattaagaa ttgctgactt tactctttct cttgcttctt taatttcttt
    18181 gcctggaaga ccaacaatat taaaactagg tattccattg cttacatcta cttcaacctt
    18241 aactaaaaag ctgtcgattc ctactaagtt gcttgaatta ataatactta acatatttaa
    18301 tcctttccaa aaacattatc ttttttaaaa agcattcatt atgtgattta ttcttttttc
    18361 taataaatat acctctataa catcaaatct tatgggagtg ttatttaagt tattttttat
    18421 aatataataa cttgcaactc caattatctt ttttcttttt ttgaagctta cagattcaca
    18481 agggtagcca aactttatgt tagaccttga tttcacctcc acaaatataa tttcatcttc
    18541 catttttgct attatatcta tttcccctat ctttaatctg taattttttt ctagtatctt
    18601 tgctcctttt gatagcaaat aattaactgc tactttttct ccaaaatcac ctttttcttt
    18661 attattcatt attcactcca atacattaaa ttttcacttt taaattatgg tcagtataca
    18721 attttactat tcaagttttt ggattgattt tatttccatc aatattaata aatacttcta
    18781 ttgactttat tcttttatga tattattcta gttttcatag gaaaagttta tttttttgga
    18841 ggagtgcctt taatgaacag agaaaaatta gttgctttta tacgatattt atctttattt
    18901 atattagttg taagctattt gaaaaatgtt gaaaatacat tgtatccggt cataactatg
    18961 ataatattat ttctaattat aataaataat caagttagat ttttttcttt atcaaatgag
    19021 aatacattta tacttatttc ttacttttta gaacttatat taattttttt actttgtaat
    19081 tatacaaaaa cttttaattc gatttacttt gttcctttaa tattagatat atcattttta
    19141 ataaaggaaa aatataagta catattgttc tcttttgtta taatatcttc tcttgttatt
    19201 agtttagata aaaacatata tttggcactg gagtcaagct ctatattgct aattataact
    19261 gtactttcta tatatataga aaatgagaat ttatcaaaat tatacagtca aaatctttat
    19321 gataagctta gaatttctaa agatgaatta aaaaaagtta atgctgattt ggaaacttat
    19381 gcaagttcta tagaagaatt agcaatttta aaagaaagaa atcgaatatc aagagaaata
    19441 catgatagtg taggacattc tctttctaca acaataatac aattaaatgc tatagaaaaa
    19501 ctcttaaaag acaaacctct aatttatgac ttagtacatg aacttagaga atttgtaact
    19561 gaaagttttc aagatgtaag aagggctata tctgagttaa aacctgttga atatgaaaat
    19621 taccaaagtt tatttaaaat caaagaatta gttaaaagct ttattaagct tacaaatatt
    19681 aatgttaaat taactatttc aaaaaatact tggaacttat ccagaaatca atctataact
    19741 ttatatagac ttatacagga atccctttcc aactcatcta ggcatggaaa ggcaactgaa
    19801 atcagaattt ttattacatt caatacttca aatcttataa ttactattag tgataatggt
    19861 ataggatgtg gcaatataaa aaaaggaaat ggacttaata gtatcaatga gagaatatat
    19921 gaattaaatg gtaaagttga atttgataat tctaataatg gttttacaat tagagcttct
    19981 tttcctaaat tttcaggggg tgattttttt gaataaaatt aaagttctta tagtagatga
    20041 cgaaaaatta attagaaaag gtcttaaaat tatattatca tcttataatg atttagaaat
    20101 tgtaggagat gcttctaatg gatatgaagc tttagaattt tgtaaaatga atgatgtaga
    20161 catagttctt atggatatac gaatgaaagt atgtgatggg gttctaggta caaggcttat
    20221 aaaggaatat aataattcta taacattatt aattttaaca acttttaatg atgatgaata
    20281 tataaaagat gctatgaagt ttggtgcttc aggatacctt ttaaaagata gctctgatga
    20341 agtattgcat gaagggattc gttcttcatt ttttggcaat attgtgcttg ataaaagtgt
    20401 agctgaaaaa atcatgacct ctgaaaaaac ggttaaacaa gagcatcttt atgacatgta
    20461 caatttaaca gaaaaagaaa tatctataat tagactaatt gcaaatggac ttaataataa
    20521 agaaataagt caagaactat tcttatctga aggtacaata aagaataaca taactaatat
    20581 tttagctaaa ctagaacttc gtgacagaac tcaactagca atctttgctt tcaaaaataa
    20641 aattgtaata gaataaatct aaaaatataa agtgacttaa gtcacttttt ttagtgactt
    20701 atagtaatag aattataatt cacaattctt tattataata ttatagcttt ttaacttata
    20761 caaaattatt ttggagggat tactatggat atagtcagag taaataatat aacaaaaaga
    20821 tttaatgata aattagtact tgataacatc agcttttctg ttaaaaaagg tgagatattt
    20881 ggacttattg gcccaaatgg tgcaggtaaa tctacactta taaatataat tacaaatctt
    20941 atgttaccaa atagtggtag tattcaaatc aatggtttag atttatcaaa agattatata
    21001 aaagcaaagt ctataatagg gttagttcca caagaattag caattataga aactcttact
    21061 tcttttgata acttagagta ctttggagct ttctacggtt taaagggaaa actacttaaa
    21121 gaaagaatca ttgaagcatt agaagttaca ggtcttactg aagtcaaaaa gaaaaaggtc
    21181 aaaaaattat ctggtggtat gcaaaggaga ttaaatattg gaatagcact cttaaatcat
    21241 cctaaaatat taatattgga tgaaccaact gtaggtgtag acccccaatc aagaaatcat
    21301 attttcaatt ttataaaaga tatatctaaa aaacatgaaa ctactgtaat atatacttcc
    21361 cattatatgg aagaagttga gcacctttgt tctaaaattt ttattatgga tgaaggtaaa
    21421 gaaattgctt ttggaaataa tgattattta aaatcactcg tatctacaaa tacaaaatta
    21481 attatggaaa taaaaaatat aaatgcccaa cttatctttg atttaaaaaa tactaaaggt
    21541 gttatatctg ttttagaaaa taattcatta ttagaattgg atatagataa aaaattacaa
    21601 cttacagata tactctctgt cattgacaaa aacaattcaa aaataatgaa aatttcttat
    21661 gaagaaccta gcctagaaga cgtattttta aatctaacag gaaaaaattt aagggactaa
    21721 tggaggtgat tttatgaaat tatacatgag tgtaaaaact atgctaaaga gtttaaaaag
    21781 ctcctttata cttaatttaa tatatttttt agctttgcct ctgattttat cttggtttct
    21841 tgggatggtt acagaaagca tgtttcaaaa ccctataaaa acagaatcta cccccattgt
    21901 tatatatgac aaagataaca caagattatc aaatgatttg acaaagtatt tgaaaaatga
    21961 tttatcttat atattaacag ttaaaaaaga tgattctaag gcagaattaa agcttactat
    22021 acctaaaggc tatgagagta gtttattaaa tgaaaaatca aatactctaa acatagaaaa
    22081 acttggaact cgtgatgata tcgcaatatt gcttcaagat atattagata cttaccatga
    22141 aaaattttat ttaaataatt ctcagaaaat aagttcagaa gatttttcta aattatttaa
    22201 taaaaattct attgatactt ctataataaa taacaatgtt aaacagagct cttatgaata
    22261 ctttgcttta gtttcactag gatttcttgt aataattttt ataatgaaca atattttgtc
    22321 aaattatata agtgaatcaa agggactttc aaaaagactt tattctatgc ctataactag
    22381 agtacaattc ttaatttatg actttgtagg tttatggatt tattcattta tattcttatt
    22441 attatatgtt ttattcttta gaatacttgg aataacattt aaaggtaatt ttgccatatt
    22501 gctcctactt tgtgctttat catcttattt tatgacttca atatctacct ttgtaaccag
    22561 cttttttagc aaaaaatacg gtacagcaat agtttatgca ttactctttt tacagacaat
    22621 ttttggaggt atcttcagta tgataagtga tacatttact aagcttacaa gtttatctcc
    22681 tacctattta ataggagaat tgtttagtaa ttatgaaaca tttaaaacta tagattcaat
    22741 aggagattta attttcacat gtttaattat ctctacaata ttaattgcac ttgctattgt
    22801 aaaggaaaat tataaatgga gggaggttta ataatgatta gattaactat tgcaaatata
    22861 aaaagatatc taaaaaatca tactctttta attaatatgg ttatgcttcc tattatacta
    22921 attttttcac ttaatttttt tatcaacaac tcgggaaatc aatcaatgta tttttctcca
    22981 gtagcaattg tatctgactc ttcaggaaag tatgaacata agttaataaa tagttctaaa
    23041 ttaaaagaaa attcatttag attaaatgaa caagataagg ctatgaatct attaaaaaat
    23101 aataaggttt ctgctgtatt cgttttagat aaaaattttt caaatagtat agataaatta
    23161 caacgacctg tagttaaatg ctttaaaatt gaaaatggtg gtggtagtct ttgggcagaa
    23221 tcacaaatag aatcttttat tactaaatcg ttaaaattga aagtggataa aaatatagat
    23281 gataaattga caaagacaaa tataattgat aacaaaccag ataagaataa aggttcattt
    23341 ttagtagtct tcttgatatg ctattttatg tatattaatg cggcacatct tgcttctgat
    23401 ttatttacat taaaaaaatc aaatgtgcta aaaagactta tctctacaga taataaagat
    23461 ataaaaataa ttttcagtat atttttagga ctatttttta ttcaatcaat tgtatacact
    23521 tttgctctat tatgtttttc aattatagaa gactttaatt tgagtctgaa tgtattgatg
    23581 attgtactag caaatagttt tgtttccact ggatttgtat tttgggtagc tagagtattt
    23641 aaaaatgaaa gttctataag tcttatatct acattttatt ctttaatagg tctagctata
    23701 tctatctcta gtctaatacc atcaatggat aaattatcct ttatgactaa tctttcaaag
    23761 ttcacaccat tttattggac tatagatgct attaaaaaca atggtagtat tttaataaat
    23821 ataatagctc taatattaat tggaattata tttgtaactg caggaagtct taaactaaga
    23881 gattttgcta aaaactaata attattaaat ataattagta tctattttta tataattgta
    23941 aaagaatatt tcaacatatt aaattatttt atcttatatt tttctcttta gtttcacaca
    24001 tcaccaagtc taaactttat attatatatt aatatttttg acttgtcaag ttatttatgt
    24061 tataatatta atcattagat aattaaagca ttgtacctaa gttgcaatat ctaaaattca
    24121 atttggaggt ataactagca tatgtataaa attggtgaaa gtgtaatgta tccaaaagag
    24181 ggagcctgct ctgtaaatga tattgtaaca aagaaaataa atcatgagat gcaaaaatac
    24241 tatgaattaa gtgtcatttt taatagtaac cttaaaattt cgattccagt tctaaatgca
    24301 gatagaattg gcatacgtcc agttatggat ggaaatgatg ttgataattt tatccaatct
    24361 attaataaaa cagatggtgt atggattttt gatagaaaag aaagacttaa actgtaccaa
    24421 gataaatttc attcaggaga tgtttttgaa attgtaaaat taatcaaaat gcttatgata
    24481 caagacagtt caaaacaatt gtgtagcaca gataaggagt ttttaaataa agctcaaaaa
    24541 tttgctttat cagaattagc tgctgctcaa tgtaaatcct atacaatggt attagaggaa
    24601 atgaaaaaac atatattaaa ttcaaagaat ataaattaaa ccagtttttt aaactggttt
    24661 tattttttat actaatcatc catgctactt tagcttattt taaactgcct aatctaatat
    24721 taataaagtt atctcaatta gatagatgta ttttattcaa ataaaaaaaa actaagagta
    24781 aatcatatta ctgatttact cttagctaat aaaatttaat cttcttcaag ttcttttttc
    24841 tcttgtaata atacacttaa ttcatttgct tctaaaactt gtgcctctgc aatatcaagt
    24901 aactcttgtt gccattccac acatttatct ttgtaatcaa aaggtagcgt tctgtcaact
    24961 atgtacttat caatacagtc ctccgcactt ttaattattt cttttctttc atcaataaat
    25021 ttttctaatt ctactaaggc ttcttcataa gcttttctac tcatataaat tccccctttg
    25081 tacaattatt ctacattaaa atgatttttc ctcttttttg tataaaattt tatttgtata
    25141 taacttttcc atcaatatct tttatagttt gacatccagt taatatcata gaactactta
    25201 gctctgattg aagtttattt acataagttt ctacaccatc agttgcacca ccaaaagaag
    25261 cagtcacaaa aggtcttcct attaatactg catctgcacc taaacctatc atttttagta
    25321 cgtctaaacc agttctcact ccaccatctg caagtattgt aactttacct ttaacagcat
    25381 cagcaatttt tggtaaaact tcacatgctc ctggtgtaca gtcaagcact cttcctccat
    25441 gatttgatac gactattgca tccacacctg cttctactgc cattaaagca tcttcaacag
    25501 tcattatacc tttcaatata aatggtagtt tagtagactt tactaactcc tttatttgtt
    25561 taacattttt aggaagtact ggttttccat gtaatgataa agttactaga ccacaggcat
    25621 ctatatcaac tccaactgca aatgcaccag cttcttcagc taatcttatc ttttttataa
    25681 tattttcatt atcccaaggt ttaataaata caattccagc tccattatac tttttgacta
    25741 catctaaatt ttccattaaa aaagcatcta ctgccgtatc accaaccatt gcataaatac
    25801 cactattagc acatcctgca actactggtt ctatgtaatc tctttcatta atttttccac
    25861 ccatatttaa agtagttcct gttactggag ctgcaaatat aggtgcactc attttctttc
    25921 caaacatctc tatagatgta tcaggatttg atacatcatg tattactctc atatttactt
    25981 ttactttttc taaactcttg ctattttcta taaaagaaga accacttcct ttacctccca
    26041 tgccaggcac ttcacctgca caagcaaccc cattacaaac cttacaaact ttacaacttc
    26101 catttaaatt ttctctagca ctttttaata attcattata ttccatcttt aatcccccat
    26161 taactatagt aatttatatt atatacatta tatcatatta tatttacagt atatttttca
    26221 aaaaactttt tctgtggata ggagttatgc catatttttc aatagcttca tagtgttctt
    26281 tagttccata tcctttgtga gatttaaacc catattctgg gtatactcta tcatattggt
    26341 acattatact atccctagta actttagcaa gtatacttgc tgctgctatt gatatagatt
    26401 ttgaatctcc tttcacaatt ggattttgag atatgtcaat acctggtatt gttgctgcat
    26461 caactaataa ataatccggt gcttttttta aacaatttat agcctttttc attgccatat
    26521 atgtagcatt taatatatta aattcatcta tttcttcatt gtttactata cctattccat
    26581 aatctagtgc ttcttctttt attacttcaa aaagttcatc tctttttgcc tcactcagtt
    26641 tcttagagtc atttacacct tctattttgg tatctttttt aaatactaca acagaagcta
    26701 caacaggtcc agcaagtggt cctcttcccg cctcatcaat tcctccaata tataaataac
    26761 ctttatcata gccttcgttc tcaaatatat ttatagtttc caatctttct tcttcttttc
    26821 taatattatc cagctttttt gctagtttta tagctagacc ttgtacagat tttctttcat
    26881 caactcttaa cagctctata tattccatat atttttctac ttctaaagtc tctattattt
    26941 ctttaatctc cctcacactt ttatcctgca taccattccc tcatctttcg tttttaaaaa
    27001 tttaattttt aaatatatta aaatttttta attagagttt aattgcatcc actatagcca
    27061 cattttaaac atatactaca tccacctgta tgtgcaattc cttcacttcc acactcaggg
    27121 cacacaaatt tttcatcttc ttcaaaattt ttatttatta tttctttggc tttttcatct
    27181 ttattatctt tttctttttt attattttta taatattctt ttttactatt ttctttttta
    27241 tcttctttat tattttcttc ctttttttca tttattaaaa ttccactcct tttacatcca
    27301 tctctaaata ttgttactcc tttaagacca gcctcccatg ccttaatata tatattgaaa
    27361 acatcttcaa ctgtagtttc aaaaggtata tttattgtag atgatataga agcatcaata
    27421 tacttttgcc atactttttg catgtttatt ctttcttcat atcctatatt catagcagta
    27481 acaaaaaaat ctggtaaaca ttcttcatct gtaatacctt tcttgtccat atactcttta
    27541 acaattggag tatatacttt ataatacaca tcctcatcat gcaagctttc agtttttctt
    27601 atatatgaaa gattaaatat aggttctatt ccaccactga tacctatcat tgtagatatg
    27661 gaacctgtag gaggtatggt taaaagttgt gaatttctaa gcccatactt tttaaccatt
    27721 tccttagtgt cttcatttag attttctata aaaaacttag atttagaaat attttcatat
    27781 ttatactcac taaatgttcc atattcttta gcaattaatg ctgattgctt cacagcttca
    27841 tttaacatag tcttaccaat taaatcacat agttctaaag attcatcaga accatatctt
    27901 attcccattt ttataagcat atcagctata cccattacac ctaaacctat ctgtctatac
    27961 ttatgtacac tatctctttg ttcttgtaat ggatgcaagt tcaatccctc atctaagaca
    28021 tcatttaaag ctactacagc ttctctaacg caagatttta atttattaat atcaaaagta
    28081 gcatgttcac caaatggttg tattataaac tctgacaagt ttattgagcc aagtagacaa
    28141 cttcctccac ttggaagtgg ttcttctgca caaggattta ctcctgaaaa gcaaaagttc
    28201 ttatcttcac tcataaaatt atatgttttt attttatccc aaaacaatat acctggttct
    28261 gcataatccc agttattttt cacaaattta ttaaataaat cataagcatt tactatctta
    28321 actatttttt ctccagtagt ttcaacttca aaagtacaat tatataactt tttttctctt
    28381 acagcttgca taaattcatc tgttactctt acagaaatat ttgctttagt aaccttctcc
    28441 aaatctgttt ttatatctat aaagtcctct atctctggat gatttacatc catagaaatc
    28501 ataagagctc ctcttctccc tctttgacca attaagccag ttgtcatact gtaaagttcc
    28561 ataaaagaga ctgctccagt cgtatgtttt gcagcattgt taactttcgc tccttttggt
    28621 cttagctttg aaatatcaat tccaactcct ccaccataac taaaagttct agcaagtttt
    28681 tttgcagtat caaatatatc ttctatgcta tcttttggtg gttctattac ataacaatta
    28741 gaatatgtta ctttttttcc ttctttctgt aatcctctat ttgctaaaat tcttccagca
    28801 aatagaaatc ttttttgtct tattagtttt gatattcttg aactattatt tgaaattctc
    28861 tttatccatt catcaaaact ctcaccatta tgtctatact tgttcttcca tattgatttt
    28921 tgtaattcat caaactccca agctttagtc cttatttcag agcgtctttc tctatataat
    28981 atgtagtgtt ttgctatatc ttttctattt gattccataa gtagtacttc aactatatct
    29041 tgtatttctt ctacggataa gcatttttcc atagaattat agtcattagc tatttttctt
    29101 gatatatcat atgccaactc tctatctact ccaccttcac tatttatact agctttatag
    29161 acagcatctt caatcttact tttactaaaa agttcttttg taccatctct ttttattatg
    29221 tacttcattt ttaaacctcc aataaattag tattaaatta atacacacat taactataac
    29281 tctaaacaaa ctttttatat atttgtatat tttcatatta attatctaac ataatatata
    29341 ttatactatt ttatatt
//
LOCUS       DAMKNB010000044        28606 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.046, whole genome shotgun sequence.
ACCESSION   DAMKNB010000044 DAMKNB010000000
VERSION     DAMKNB010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 28606)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28606)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28606
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.046"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            complement(190..558)
                     /locus_tag="PC494_002183"
     CDS             complement(190..558)
                     /locus_tag="PC494_002183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HDF3912682.1"
                     /translation="MKKIPKSELLVMNFIWDKGIDKIPAREVANYMEISHGWTKGTTG
                     KVLSRLSDKGFLEFEKDGRNTLYTIKVKHEEYLKFETKDFLELIHKNSIHSFISSLGC
                     GNEISDDDIKELEQWLKKRK"
     gene            complement(1086..1508)
                     /locus_tag="PC494_002184"
     CDS             complement(1086..1508)
                     /locus_tag="PC494_002184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3284 domain-containing protein"
                     /protein_id="HDF3912683.1"
                     /translation="MNTFKTEVLLKYSAKDIFNIFTKSARLNFPNFNEKKAVGTFVQQ
                     KNNKRFKVEITNFEKNRVYEIKTSNKRESTITRYELVHIDLENTKLIFIESESKRNIF
                     GKINSALVRVLFGKRQPEEFNKFIKKLEMELENNSVNL"
     gene            1986..4889
                     /locus_tag="PC494_002185"
     CDS             1986..4889
                     /locus_tag="PC494_002185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDF3912684.1"
                     /translation="MELRDKLVNIINTENKKDPLTDVQIAKFLSTTRENITNLRKELN
                     ISNSRQRRYPYLKSAISAILQKNKNISISEITRELMTEGFNISRRVVEELLPKESLEM
                     DVVEEDEEESNDPFETLIGNKGSLRNAVEQAKSAILYPPKGLPTLIIGESGVGKSLFS
                     RHMYEFAKQKKIVKESSNFVVFNCADYSDNPQLLLSLLFGYKKGAFTGAEYDTPGLVE
                     EADEGVLFLDEIHRLPPKGQEILFSILDRGKFRRLGETNAERKVSIMLIGATTENVET
                     NLLLTFRRRIPMLITLPPLHDRLLKEKIDLIYNIFQQECNRINAKIFVDKNVIEILAL
                     KKFSGNIGQLQNMIQVLCARAFMKFINSKDEDSESIVVVDINEVLKLKDSFKDAAFQE
                     IEYTEIRKYLKNAIFIPFNLEESSVKGSLLSDEYILPEDIYKTIEKKYYDLKSLDIED
                     IDIENILWTFILNRFADLKFNLDSNEEIFSMSDLNSFVSDSLVKLVKELMNDIVEKNM
                     NLEVNKNMFKYLAIHLEEAIKRIKLNQKIINVNLEKIKIDFSKEYEISKSFAIKIEES
                     IGIKISDDEIGFITLYIKSALKNEVKKDKVGLIIISHGRIATETVNVVKELLGVKFPV
                     AIDMPLDEKPINIYNKAVELSKIIDQGKGILFLVDIGSLTNIGQIVNKRTNISTKTID
                     RVDLLMALEATRKVSMGEEELDEIFFSLLKDRMGYNYELEKHIDKSNAIITLCLTGEG
                     TAKYISKTLEEKYDNTKCYQMSALDESLFCKIENLKETNNILAIVGTINPKIPGINFI
                     PYNKELFKNLDIYLSKSKQQDDRPIKSYERMLDEDLVIFEPDIYFKKDLLEYVCSILI
                     NKEYVEKDYLDSVLHREEMLPTYSKGAIGVPHGDSSTVNSTRFVFVKLKNPIDWGVGN
                     VNFIFMPVFQANDKEIVKNVLEILKDAEFMNNANKCFDKDAFRRIIFDKFKHL"
     gene            4922..5368
                     /locus_tag="PC494_002186"
     CDS             4922..5368
                     /locus_tag="PC494_002186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDF3912685.1"
                     /translation="MNVDLISLGLESNDYESVIEELGSIMCKKEYVKETYINAVLERE
                     RTLPTGLDIGDMCVAIPHTDSKHVNESNVAVGILKNPVKFNSMIDPKDRLDVELVFLL
                     AVKNPDSQVKLLKDLMSVFQNIKLLKNIKNASTKEEVAKLLDFIEI"
     gene            5491..5793
                     /locus_tag="PC494_002187"
     CDS             5491..5793
                     /locus_tag="PC494_002187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDF3912686.1"
                     /translation="MKQFNVLSVCGSGTVTSSMVAGKLKEVLGNKGISITTTEARPTE
                     ALNLAQSGRFDFITFTSPLQTGDYGIPTINAFACLTGIGEEAFFEEVLTVIEGIDK"
     gene            5974..7380
                     /locus_tag="PC494_002188"
     CDS             5974..7380
                     /locus_tag="PC494_002188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HDF3912687.1"
                     /translation="MLEFMKSIIDTFGSAIIVPIIIFIIAKIFKVTTKKSFLSAVYAG
                     VALQGFTLILNSFTPVITPVINRMVESTGVNLPVFDVGWQATSLVAFSTSAGMIYLGL
                     GILLQTILFLIKWTDVFQPSDLWNNYSYMVWGAMVIGVTGNFPLGIACMVLLNLYSLL
                     ISELVAKRWSSYYRYPNCTIIAMHNVEASVFAVFADPIYNKLGLNKMKLNPKELEKKL
                     GFLGEPITLGLFLGMFIGILGNMTRINTMEAWGEIMKVGISTSAVMAIFPKVASMFAQ
                     AFAPITEAARKIMQKAGNREWYIAVNDAVGYGEPATLISGLILIPIMLVIAMVLPGNK
                     VLPVVDLLAIPYMVQGLVAIHNGNIPKVLVSGIIWFGLGLYVCTSTAPLFTDMATNIG
                     VAIPAGAMLITSFNILGKPLMGLVFFAFLSANPIYIGLSVVIYFVLWALFRKNKTSIL
                     DYLEKQALKNVEEEPVAV"
     gene            7724..8782
                     /locus_tag="PC494_002189"
     CDS             7724..8782
                     /locus_tag="PC494_002189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012101107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HDF3912688.1"
                     /translation="MGDKMRASVLYNVGDVRYEMVDIPEITDTQVLVNVKYVGICGSD
                     LPRSMVSGLSGNTKYPLILGHEFSGEVVKIGEKVKHINVGDRVAVAPLVPCGKCDYCN
                     EGNFGLCDDYNIIGTRVNGAFAEYVRVPEEHILKLPDTLDYETAAGIEPATIAYHGIS
                     KSNIRVGDSVVVLGCGPIGQFVIQWAKVFGASKIIAVDIFDEKLELSKLLGANYILNS
                     KEVNVIKEIKKITNGGADVVIETAGSRFTQEQSLFVAKKRGNIVFVGISHTELPLSAD
                     ATECILRGELTLKGSWNSYTSPYPGRAWTATLDFMGKGDIIFKPMISHKIGLNEVGDF
                     LSKMSKREINFNKILVEI"
     gene            8881..9567
                     /gene="araD"
                     /locus_tag="PC494_002190"
     CDS             8881..9567
                     /gene="araD"
                     /locus_tag="PC494_002190"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HDF3912689.1"
                     /translation="MLENLKEEVLKANLELPKKKLITYTWGNVSGIDREKGLVVIKPS
                     GVEYSNMTVEDMVVVDLEGNIVDGKLRPSSDTPTHLVLYKEFEELGGIVHTHSSWATI
                     WAQIGKSIPSCGTTHADYFYGSIPCTRKMTREEIRNEYEKETGNVIIEEFMGRNPIHC
                     PGIIVNDHGPFTWGKDANEAVHNAVVLEEVAKMAYYTELMSPDNIMDKVLMNKHFSRK
                     HGKNAYYGQK"
     gene            9585..10232
                     /locus_tag="PC494_002191"
     CDS             9585..10232
                     /locus_tag="PC494_002191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II aldolase/adducin family protein"
                     /protein_id="HDF3912690.1"
                     /translation="MLDSLKGKVVEIAIKAEHYGLCKEKTGNFSIRDKDTGYILITPS
                     GVGREELKVEHICVLDLDGNVIEVEKGIKPSSEVLMHIEIYKTRENINAISHTHSLYA
                     TAFSVAKKPIIPIVYESVNYGGYVDIAPYERPGTLKLAKSVSKLLIDTDACLLERHGL
                     TTVGNDLDEALLKSRYVEEVAEIYYRSLVLNQFKELEVVDVDEFKSWKYPEEIKF"
     gene            complement(10405..11772)
                     /locus_tag="PC494_002192"
     CDS             complement(10405..11772)
                     /locus_tag="PC494_002192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:alanine symporter family protein"
                     /protein_id="HDF3912691.1"
                     /translation="MNLIDILNKVDAFIWGPPLLVLLVGTGILLTVKLGVVQITKLPR
                     ALKLIFSAENKGSGDVSSFAALCTALAATVGTGNIVGVATAIKAGGPGALFWMWIAAF
                     FGMATKYSEGVLAIKYRTKDKNGQVSGGPMYYIVNGMGEKWRPLAIFFAISGILVALL
                     GIGTFTQVNSITDAINNSFGIDPRITGVVLAVFVALVVFGGLKSISNVATKIVPFMAV
                     IYVVICGIILISFWNKIPETFMLIIKSAFTPTAATGGFLGATMSLAIRNGIARGVFSN
                     ESGLGSAPIAAAAAKTEWPAEQGLISMTGTFIDTIIICTLTGFSLVISGVWCSDLNGA
                     VMTQAAFNGAIPTFGPILLTVSLTLFAFTTILGWSYYGERCFEFLFGVKGMNGYRTVF
                     VAMVLLGAFLKLEVVWIIADIVNGLMAIPNLIALLALSPIIVSETKKYFEHINSPENQ
                     IKKNA"
     regulatory      complement(11962..12050)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            12478..14598
                     /locus_tag="PC494_002193"
     CDS             12478..14598
                     /locus_tag="PC494_002193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HDF3912692.1"
                     /translation="MGKILVLAEKPSVGRDIAKVLGSKNEKNGYIEGPKYVITWALGH
                     LVTLADPESYGERYKSWSLEDLPILPKHLKTVVIKKSGKQFNTVKSQMNRNDIDEIVI
                     ATDAGREGELVARWIIEKSQVKKPIKRLWISSSTDKAIKDGFAKLKSGKEYENLYYSA
                     IARAEADWIIGINATRALTTKYNAQLSCGRVQTPTLAMLLKREEEIRNFKPKEYYGLE
                     LIATKGNSDIKFIWNDKNNNSSTFSKEKIESTLKKVKGVDIKISEVNKSYKKKYSPAL
                     YDLTELQRDANKMFGFSAKETLSIMQKLYEHHKVLTYPRTDSRYLTSDIVGTLKDRIK
                     AVNISDYSKICNRLLKSNIIANKSFVDNSKVTDHHAIIPTEQKVFMSDFSDKERKIYN
                     LVVKRFLAVLSPPFEYEQTTISATVEGEIFKAKGNKVINLGWKESYKDIEDEDEYESI
                     PNVLEKDVLKVKGLKITSGKTNPPPYLNEGTLLTAMEKNGLGTVATRADIIEKLFNSF
                     LMEKKNKDIYITSKGRQLLDLVPVDLKTPELTASWEKKLLDISKGKLSKNTFINDMKD
                     YSKDIVLEVKNSDNKFKHDNLTKNRCPECGKFMLEVNGKKGKMLICEDRECNTRKTIS
                     QVTNSRCPNCHKKLELRGEGEGRIFTCSCGYREKLSSFNKRKQEEKQKASKKDVNQYL
                     KNQNKNQETFNNPFAEALAKLKNK"
     gene            14702..15955
                     /locus_tag="PC494_002194"
     CDS             14702..15955
                     /locus_tag="PC494_002194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar protein FliS"
                     /protein_id="HDF3912693.1"
                     /translation="MDLSGIFKYYCKECENTWNNSSVELFENIETYSKDSQKKREKEL
                     DKLLNTISVHLERYPSDAVLRKMWVKKGEVFLQKTLEKENIFKLEKMDVEDRKKFLDI
                     TKQFIRDARKFDDDLPIGDIMQAMRNVWISNALQLLFGKEVYYSKANFAYSMLYPYTD
                     NYLDNTNIDKNDKILFNNWLEKRLLGEHIKSKDYHESKVSQMIDYIESVYPREKFTEV
                     YESLLLIFKSQVNSLKQHGKENHLCKEDLLSISIEKGGSSVLVDGYLISGLMTKEEIE
                     FCIGYGFLLQISDDLQDIKEDLKYNHKTIITEMSKEGTLDKVVNKLINFTIELIDSFK
                     INNKNKSVITMIKNDCLMLILFSVVYNAEFFSVGYIKEVEKFIPYTIDYSLEIEEKIK
                     EKFKNIDVLNNENEYKEMIDIICAE"
     gene            complement(16109..17170)
                     /gene="ytvI"
                     /locus_tag="PC494_002195"
     CDS             complement(16109..17170)
                     /gene="ytvI"
                     /locus_tag="PC494_002195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation integral membrane protein YtvI"
                     /protein_id="HDF3912694.1"
                     /translation="MDIQKQKNFIIKFTYVVLITSIVYIVLKFLLPLLMPFVISFIIA
                     SILRPIIRLITNNTNLNRTLISIVILLIFYGLCIFLLVSFGVKIFASVSDVFFRLPEI
                     YKSSIQPTLNTLFSKIDASTPNVNLALILGWDNISQSMMSLVASISTNALNAIASIAS
                     KTPAFMLKLIITLIASFFFTFDYQKIVNFILKQFPEKSQFMIINIKNSSINALLKLLK
                     AYAILLSVTFIELLIGLTILKVENAFTISVIIALVDILPVLGTGSILTPWMIISLING
                     NINLAIGLLILYIIITVVRQILEPKVVGHQIGLYPLITLMCMFVGAQLFGIAGLFGFP
                     IAATIIKNLHDNGIITAFK"
     gene            17444..18184
                     /locus_tag="PC494_002196"
     CDS             17444..18184
                     /locus_tag="PC494_002196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-protein phosphatase"
                     /protein_id="HDF3912695.1"
                     /translation="MKNFRDLGGNKTEDGRTVKKGLFYRSAKLSNLSENDIKILRELN
                     IKYIFDYRSDEEARKHPSTIISNIKNIRIPAMRELEESGGSFGSIEDMIDGLFEKDGA
                     FNMLNNSYYNLPINNPSYKKLVELIRDYSNLPILNHCTAGKDRTGVGSAIILMILGVS
                     RENIMKDYLKSNDFADKEIERFIEYKPKFKDIPKENLKYIFGVNEEYMKTAFRRIDEE
                     YISVEAYLYGEFNLNKEEIRKLRNQYLE"
     gene            18196..19974
                     /locus_tag="PC494_002197"
     CDS             18196..19974
                     /locus_tag="PC494_002197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HDF3912696.1"
                     /translation="MSLNITARQINIIKILLNSKDTISGIALSQEIGCSSKTIQNEIK
                     DINKQLRNGKILSIRGVGYKLEGSFDEVNLNSNLYDDVDRVEYIIRKILTLSNEEKNT
                     IKLEDLADSMYVSVSTVKNDLKEVKRMLEKYSISVKSKHKQGICVLESEDKILNCIVD
                     LSNKRDNQLSLNDFLNDDIKERKLLIKKLLLDILNENGLVLTDIEFKSVLNNILVMLS
                     RHKYNEKEFIENYIENYRSKRSSILENEQNKEIIINSIKTFCKNLKLATSIDISNDKV
                     FEEFLYKHISSLCKKIKLGINQSPIMAQDIKIKYPFAFELANIAKKTIEKDLKIEINE
                     DEVANIALHIGGAVERASYNNKDKVFKTIIVCTSGIGTSMLIKAKLENIFKEKLEILK
                     IIPSYLVEYIKVIDVDFVISTVPIEVGDVPVINISPILSEKEIRLIEKYIETGNIYLD
                     LDIKSLFDSELFFTDLVFKRKEEVIDFMASKLVQKGYIDEDMKKSYFEREKIATTEIG
                     NMVTIPHGAIGKIFDNKIAIGILKKPISWEISDVRLIIMLALDKDKILDYEVIFSKIY
                     KRVDSIAKVISICENSSFEKFVNLFN"
     gene            20141..21058
                     /gene="pfkB"
                     /locus_tag="PC494_002198"
     CDS             20141..21058
                     /gene="pfkB"
                     /locus_tag="PC494_002198"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HDF3912697.1"
                     /translation="MIYTVTLNPSIDYIVKLDELKTGSTNRVKEEYVYPGGKGINVSR
                     ILKELGNDNTSLGFISGFTGEYIIRTLEEKELKTDFIKIKSGFSRINVKIKALKETEI
                     NGQGPNIDDEDIDTLYKKLDKLNQDDILILAGSIPSTLDEKLYENIMARLEKKNIKVV
                     VDATKNLLLNVLKYKPFLIKPNNDELEELFGVKLNSIEDMVKYARRLKEMGAINVLVS
                     MGKDGALLITEEDEVLISDVPKGKVKNSVGAGDSMVAGFISGYLNTGKYDYALKLGAA
                     SGSATAFSYDLAKREYIDKLVNEISVKQF"
     gene            21095..23014
                     /locus_tag="PC494_002199"
     CDS             21095..23014
                     /locus_tag="PC494_002199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDF3912698.1"
                     /translation="MKIIDLLDEKSIKLNLNSKTKSEAIEELVDLVANSGNLNDKENY
                     KKAILAREEMSTTGIGEGVAIPHAKNSSVTKACIAAAVSKEGIDYESFDGSLSNLFFM
                     IAAPDGANNTHLEVLSRLSTILMDEDFRNKLINSSSEKEFKEIIDKKEREKFSEEYQD
                     EKVTEKNIIDTKENDANKYPKVLAVTACPTGIAHTFMAAESLNKMAENKGVSIKVETN
                     GSAGVKNKLTKDEIENATCIIVAADKNVEMARFNGKKVIKTKVADGIHKAEELIDKAV
                     NGDAPIYHGGDGSHNESNEESESGFRKVYKHLMNGVSNMLPFVIGGGILIAIAFLLDD
                     YTINPSNFGSNTPIAAFFKGIGDKAFGFMLPVLAGYIAYSISDRPAFVVGFVGGALAG
                     DGGSGFLGALLAGFIAGYLVEGLKKIFSVLPASLEGIKPVLLYPLLGTLLMGIIMTFL
                     VIPPVTAINNAMVGFLNGLGGTSKIVLGLVLGGMMAVDMGGPVNKAAYVFGVASLESG
                     QFEIMAAVMAGGMVPPLAIALATTFFKNRFTKEERDSGKVNYVMGLSFVTEGAIPFAA
                     GDPLHVIPACVGGSAVAGALSMLFNAALRAPHGGVFVIPVVTHPFAYILAIAVGALVG
                     MMLLALLKKPLNQEV"
     gene            23610..25136
                     /locus_tag="PC494_002200"
     CDS             23610..25136
                     /locus_tag="PC494_002200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HDF3912699.1"
                     /translation="MNESYWFLNSSPKEYNKLGENIKTDCLIVGGGITGLTTAYLLAK
                     EGKKVVLVEADKIGYGTSGRNTGKVTCQHDIFYSKIEKKYGLDKAKSYYNANNEALNL
                     VEQIIEENNIKCDFKRETSFVFTEKEDTIKDIKDEYRTCKKIGINCEYHETIENIPLD
                     IKGAISFTNQGQFNPKKYIDGLAKAAVNLGLKIYENTPVVDLEKGKICRVKTREDNII
                     EAENVIISSHSPWYDGLNFYFAKEYAERAYLMVAVLENKLADGMFISIDDPSITFRQY
                     NDGSENLLIFGGGDHKVGQGGTEKEIFDDLEHYGKEVFKVKDFKGKWSAQDNMSFDNV
                     PYIGYINKREDNIYVATGFSKWGITNGTAAGIIIKDLIINNNSDYKDTFNPSRLGSYF
                     SKDFIKENANVAINYVSGKLKIGSGDMPKNNGEGKIVNIDGKRYGVYKDDNGDFYIVD
                     TTCTHLGCELNFNSEEKTWDCPCHGSRFDYKGNILEGPALKPLKLYGHGDNDVNPKLL
                     "
     gene            25164..25721
                     /locus_tag="PC494_002201"
     CDS             25164..25721
                     /locus_tag="PC494_002201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3912700.1"
                     /translation="MNKLLKPITILLYIVYILSAVFFVANKEYGSLGLVAISLVGTFI
                     LSFINKQTERLLSKELYIMLALFIMFSSLLGTCFNFYDINYYDDFLHLWSGIISCIVA
                     FSIIKYFYTQREISKMSKVFLVIFLFMFSMGVASLWEIGEFLMDTFVGTTTQAGGLED
                     TMIDMVDALIGTIITIPFIVKKSNI"
     gene            26243..27280
                     /locus_tag="PC494_002202"
     CDS             26243..27280
                     /locus_tag="PC494_002202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3912701.1"
                     /translation="MLKKWFGIVKKRQKSESVKEEGEVILKNEKILSEEKLIDEEGVV
                     VNIDNQILTKVVNDDNEIEEKIIEEDLLISENTIKLDDKEAIINDKNIELCKKEVQVE
                     SEKIGLNKFEGLDQNENYNLEKNVIEEKKVSECLTEEDLEYIKEIKIKRGKSIKAINL
                     YTKEEWVFDTHIQCSKKLKVPLGYIRENLKYGYMDYFGDAINYLSEVLNIDEYCKSEW
                     SYLDNSKSPSEIFNILNNKIFSIRLSNEKRNEILTNDKIEALKMNYRFECIDEEYDEY
                     FKKYKSIIKRGGKKKVELVNKKGDILEIFKSLEECAIYLQKEKNEVIQMLKYGDTKVG
                     RNFIRYSLRSI"
     gene            27391..28533
                     /locus_tag="PC494_002203"
     CDS             27391..28533
                     /locus_tag="PC494_002203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HDF3912702.1"
                     /translation="MSEEKNPKENTLDESKNSDNVNSKKDDVSDEKNTDNKVKKREIK
                     LNNKTLKAIVAIVAVGAICLGGGYVFGKEAGRKLPATSKHYNSSEVVATIGDKKITGE
                     MLRKRMEPLFYLNAKTTMTDDEIRSYESNMIETMITSDILSSEAAKEKISITNDQLDA
                     QYNNLMSSIESAMGMTKEEFLKQFDLTEKYIKDDMKKELVASKYLNEKSKVTDKEAEN
                     YYNKNKSNYLQVRASHILIKTVDDKGKQVSSSKKAELKKEAEEILKKAQAGEDFATLA
                     KKYSEDSSAESGGDLGFFGKGQMVESFEKAAFALKKGEVSNKLVESDYGYHIIKKTDE
                     KYQPFEEVKSDLVSSLTSEKQNLLIQNLKEKYNVKITDKYQMKAKE"
BASE COUNT        11530 a         2954 c         4875 g         9247 t
ORIGIN      
        1 atttaatata tttaaattta ttttagatat aaacatcatt ctgactacta ttaaaagaca
       61 tataaaataa ttaaacttaa aagtatattt gcttatcttt ttagtaaata aaatgaaaaa
      121 aagaattagt ggacttatgt aaatattaaa tttaataact tctataaata attccataaa
      181 atacgtctcc tattttcttt tttttagcca ttgttcaagt tcttttatgt catcatctga
      241 tatttcattt ccacaaccta atgatgatat aaagctatga atagaatttt tatgtataag
      301 ctctaaaaaa tcctttgttt caaattttag atattcctca tgtttaactt taatagtgta
      361 taaagtattt ctaccatctt tttcaaattc taaaaaacct ttatcactta atctagaaag
      421 tactttacca gtagtacctt ttgtccatcc atgagaaatt tccatataat tagctacttc
      481 tctggctggt attttatcta tgcctttatc ccatatgaaa ttcataacta acaactcgga
      541 ttttggtatt tttttcaata taatcactca cctttaactt gattatatta gacaaatgtc
      601 taatagtcaa tataatatat catcatgtat aaataatctt tatattattt tatgcttgag
      661 aactaagtag tatagattta tagataaaaa agatattgag agttttatgg aagaggggaa
      721 tatattttct attagagata agaatatgac atatattttt tattgatttg tacaaaaata
      781 ctatatagtg aataaattaa tatcttttct aaattagaag aggagaatct tattagataa
      841 agattatcct ctttattgaa agtttaaggg atattagaga ttattaattt ttctctcttt
      901 ttttaactaa aagcaataat acataaaatt attattgcta atgatactct taatgtggta
      961 tatagtcata gtgtcacatg tttatcaata gttttttcat taattattgt aacgaatagt
     1021 aggactcata aaatacttag aaatatgttt ttagatagat tttaaatata taatctaact
     1081 tatatctata aattaacact attattctcc aattccattt ctagtttttt tataaattta
     1141 ttaaattctt ctggttgcct ttttccaaac aatactctta caagagctga attgattttt
     1201 ccaaatatat tcctcttgct ctcactttca ataaaaataa gttttgtatt ttctaagtca
     1261 atatgtacta attcatatct agtaatagta ctttctcttt tattgcttgt ttttatctca
     1321 tatactctat ttttttcgaa attagttatt tcaaccttaa atcttttatt atttttttgc
     1381 tgtacaaatg ttcctactgc ttttttctca ttaaaattag gaaaatttag tcttgcagat
     1441 tttgtaaata tattaaatat gtcttttgca gaatatttta ataaaacttc agttttaaat
     1501 gtattcatat cgttttccct tctgtatata aatttaatat ttataagtta atttttaagt
     1561 taaaatagta taatatgcca tattaaatca tgttaaaact atttatatag ctaaaatctt
     1621 acctatataa gtatgtatac tatcatataa aaataaaatc ttaaaataga aagggttaaa
     1681 aacacagttt attataattt ttattgttga gtagatacgt actattatat atgattgagc
     1741 aagtttttca atcataaatt tataaagtat tttgcattaa aatttaaaca aagaattaaa
     1801 ttatttaaga ttatgaataa ctaatacatt tagtaaatta ctaaatatac aaaatgtaaa
     1861 tacttatcaa aatgtataaa tacttatgac atctagttac ttacagggtt taagtagaaa
     1921 aaaatatcaa agtaagtatg gcatgatagt tgcttatata tttatcaaga aaggagttat
     1981 taagcatgga gttgagagat aaacttgtaa acatcataaa tacagaaaat aaaaaagatc
     2041 cattaacaga tgttcaaata gcaaagtttt taagtacaac tagagagaac ataactaatt
     2101 tgagaaaaga acttaatata agtaattcaa ggcaaagaag atatccttat ttaaaatcag
     2161 caatttcggc aatattacaa aagaataaga atatttctat atcagaaatt acaagggaat
     2221 tgatgacaga aggctttaat atatcgagaa gagttgtgga ggaactttta cctaaagaaa
     2281 gtttagaaat ggatgtagta gaggaagatg aagaagaatc gaatgaccca tttgaaactc
     2341 tgataggtaa taaagggagt cttagaaatg ctgtagagca ggctaaatct gctatattgt
     2401 atccaccaaa agggttacca acgttgatta ttggggaaag tggagttggt aagagtttat
     2461 tttctagaca tatgtatgag tttgcaaagc aaaaaaagat agtaaaagag agctccaatt
     2521 ttgttgtatt taactgtgct gattatagtg acaatccaca attattatta tctttgttat
     2581 ttggatataa aaaaggtgca tttacaggtg ctgaatatga tacaccaggt cttgtagaag
     2641 aagctgatga aggagtttta tttttggatg aaatacatag attgcctcca aaaggtcaag
     2701 aaatactatt ttctatctta gataggggaa agtttaggag attaggtgaa actaatgctg
     2761 aaagaaaagt aagtattatg ttgattgggg caactactga aaatgtagag actaatttat
     2821 tattaacatt cagaagaagg ataccaatgc taataacttt gccaccatta catgatagat
     2881 tactaaaaga gaaaatagac cttatataca atatctttca acaagagtgt aatagaataa
     2941 atgcaaaaat atttgtagat aaaaatgtga ttgaaatact tgcactaaaa aagtttagtg
     3001 gaaatatagg acaattacaa aatatgattc aggttctttg tgcaagagct tttatgaagt
     3061 ttataaattc caaagatgaa gatagtgaat ctatagtagt agtagatata aatgaagttt
     3121 taaagcttaa agattcgttt aaagatgctg cctttcaaga gattgaatat acagagataa
     3181 gaaaatattt gaaaaatgct atatttatac catttaattt agaagaatca tcagtaaaag
     3241 gaagtctttt aagtgatgaa tatatattac cagaggacat atacaaaaca attgaaaaga
     3301 aatattatga cctaaaatcc ctagacattg aagatataga tatagagaat attttatgga
     3361 cttttatttt aaatagattt gctgacttaa agtttaatct tgatagtaat gaagaaattt
     3421 tttcaatgag tgatttaaat agttttgtaa gtgatagttt agttaaactg gtaaaagaac
     3481 ttatgaatga tatagttgaa aaaaatatga atttagaagt aaataaaaat atgttcaaat
     3541 atctagcaat acacttagaa gaagctataa aaagaattaa gctaaatcaa aagataataa
     3601 atgtaaattt agaaaaaata aagattgact tttcaaaaga atatgaaatt agtaaaagtt
     3661 ttgcaataaa aattgaggaa tcaattggta ttaagatttc agatgatgaa attggattta
     3721 taacgctcta cataaagtct gctctaaaaa atgaagtgaa aaaagataaa gtagggttaa
     3781 taataatttc tcatggacgt atagctacag agactgtaaa tgtagttaaa gaacttttag
     3841 gtgtaaagtt tcctgtggct atagatatgc ctttagatga aaaaccaata aatatataca
     3901 ataaggcagt agaattgtca aaaataatag accaagggaa aggcatattg tttttggtgg
     3961 atattggttc acttacaaac ataggtcaaa tagtaaataa gagaaccaat ataagtacta
     4021 aaactattga tagagtagac ctcctaatgg cactagaagc aactagaaaa gtttctatgg
     4081 gagaggaaga acttgatgaa atattttttt ctttgctaaa agataggatg ggatataact
     4141 atgaattaga aaaacacata gataaatcaa atgcaattat aacattatgt cttactggag
     4201 aaggaactgc taagtatata agtaaaacgt tggaagaaaa gtatgataac actaaatgtt
     4261 atcaaatgag tgcattggat gaaagtttat tttgtaaaat tgaaaatcta aaagagacaa
     4321 acaatatatt agctattgtt gggacaataa accctaagat accaggtata aattttatac
     4381 cctataataa agaacttttc aaaaatttgg atatctatct atcaaaatca aaacaacaag
     4441 atgacagacc aattaaatcg tatgaaagaa tgcttgatga ggatttagtg atttttgaac
     4501 cagatatata ttttaaaaag gatttattag aatatgtatg ttcaattctt ataaataaag
     4561 aatatgtaga aaaagattac ttagattctg ttttacatag agaagaaatg cttccaacat
     4621 attctaaagg agctataggt gtgcctcatg gagattcttc tactgtaaat agtacaaggt
     4681 ttgtttttgt taaactaaag aatcctattg attggggtgt aggtaatgta aatttcatat
     4741 ttatgccagt ttttcaggct aatgataaag agattgttaa aaatgttctt gagatactaa
     4801 aagatgcaga atttatgaac aatgccaata agtgttttga taaagatgct tttagaagga
     4861 ttatatttga taaatttaaa catctgtagc catagcaaaa aaattgagag gagttagagt
     4921 aatgaatgta gatttaatat cattgggttt agaatctaat gattatgaaa gtgttattga
     4981 agaattagga agtataatgt gtaaaaaaga atatgtaaaa gaaacataca taaatgctgt
     5041 cttggaaaga gaaaggacat taccaacagg tctagatatt ggagacatgt gtgttgctat
     5101 tccacataca gattcaaagc atgtaaatga gtctaatgta gctgtaggga tattgaaaaa
     5161 tcctgtaaag tttaattcaa tgatagaccc aaaagataga cttgatgtag aacttgtatt
     5221 tttattagca gtaaagaacc cagactcaca agtaaaactg ttaaaagatt taatgtcagt
     5281 ttttcaaaat ataaagttat taaaaaatat aaaaaacgca tcaacaaaag aagaagtagc
     5341 taaattattg gattttatag aaatttaatg taggagaatt ttataaataa aaaattaaaa
     5401 tttaaacaat caaagtaagt attatttttt taataggttt aatcttatat aaaataaaaa
     5461 tttagagtga aaaattagga ggaaattatt atgaaacaat ttaatgtatt atcagtttgt
     5521 ggttcaggga cagttacatc atctatggta gcaggtaaat taaaagaagt actaggtaat
     5581 aaggggattt ctattactac aacagaagct agaccaacag aagcactaaa tttagcacaa
     5641 tcaggaagat ttgactttat aacatttacg agtccacttc aaacaggcga ttatggaata
     5701 ccaactataa atgcatttgc ttgcctaact ggtatagggg aagaggcatt ctttgaagaa
     5761 gttttgactg ttattgaagg gatagataag taagttttgg agacgtgaat ttatagtatt
     5821 taaatcaatg atttagatac tataataagc taatattaac taaatatttg tggaaaaaac
     5881 attttatatg ttgtcataaa ttaaaaaatt ataaaaatag tcacttaagt attaaattaa
     5941 gcttataaat atttataagt aggagggaaa aagatgttag aatttatgaa atctataatc
     6001 gatacatttg gttctgcaat tatagttcca attataatat tcataatcgc aaagatattt
     6061 aaagtaacta ctaagaaatc gtttctttct gctgtgtatg caggagttgc tttacaaggt
     6121 tttacactga ttttaaattc atttacacca gtaataacac cagttatcaa taggatggtt
     6181 gagagtacag gagtaaacct accagttttt gatgttggtt ggcaagcaac atcattggtt
     6241 gcattttcaa caagtgcagg tatgatatat ttaggtcttg gtatattatt acaaacaatt
     6301 ttatttttga taaaatggac agatgtgttt caaccatcag atttatggaa taactattct
     6361 tatatggtat ggggagcaat ggttatagga gtaacaggaa attttccttt aggtatagca
     6421 tgtatggttt tattaaacct atatagttta ttaatatcag agttagttgc aaagagatgg
     6481 tctagttact atagatatcc taattgtaca ataatagcta tgcataatgt tgaagcttct
     6541 gtgtttgcag tatttgcaga ccctatatac aataaattgg gattaaataa aatgaaatta
     6601 aatccaaaag aattagagaa gaaattaggg tttttaggtg aaccaattac tttaggtctt
     6661 tttttaggta tgtttatagg tatattaggt aatatgacga gaataaatac tatggaagct
     6721 tggggagaaa taatgaaagt aggtatatct acaagtgcag tgatggcaat tttccctaaa
     6781 gtagcaagta tgtttgctca agcatttgca cctataacag aagcagctag aaagattatg
     6841 caaaaagctg gaaaccgtga gtggtacata gcagtaaatg atgctgttgg atatggtgaa
     6901 cctgcaactt taatatcagg tcttatatta attccaataa tgcttgtaat agctatggta
     6961 cttcctggta ataaggtatt accagttgtg gatttattgg caattccata tatggttcaa
     7021 ggtttagttg ccatacataa tggtaatata ccaaaagtat tagtttcagg tataatttgg
     7081 tttggattag gattatatgt ttgtacatct acagcaccat tatttacaga tatggctaca
     7141 aatataggtg tagctatacc tgcaggagca atgttaataa caagttttaa tatactagga
     7201 aaacctttga tgggattagt tttctttgca tttctaagtg caaatccaat ttatataggt
     7261 ctttcagttg taatttactt tgttctatgg gcattgttta gaaagaacaa aacaagtatt
     7321 cttgattatt tagaaaaaca agcacttaaa aatgtagaag aagagcctgt agcagtttaa
     7381 gtttataaaa atgaaataaa aataattaaa ggagtttata attgatttta tataagtatc
     7441 agataatacc tgagaaatat ttaaatgaaa tatagacttc tttttatttg ataatatttg
     7501 taattataat gcattgtatc tttatagttg agttttctgt ataacctgct atttaaaaca
     7561 tactctttta tatttataca gtaatgtggt ttaattttat aaaatgtaat ctctactggt
     7621 aaaagacttt gtatataagg catttgcctg aataaaccat ttatcttttg tatggcatag
     7681 atattgctat atagaagtat atagtatgaa aggagatatt tatatgggag ataaaatgag
     7741 agcatcagta ttgtataatg taggtgatgt cagatatgaa atggtagata taccagaaat
     7801 aacagatacg caagtgcttg taaatgtaaa atatgttggg atatgtggtt cagatttacc
     7861 taggtctatg gtaagtggtt tgagtggaaa tacaaaatat ccattgattt tagggcatga
     7921 attttctggt gaagttgtta aaattggaga aaaagtaaag catattaatg taggagatag
     7981 agtagctgtt gcaccattag taccttgtgg aaaatgtgat tattgtaatg aaggtaattt
     8041 tggcttgtgt gatgattaca atataattgg aacaagagta aatggagcgt ttgcagaata
     8101 tgtaagagtt ccagaagaac atattttaaa actaccagat acattggatt atgaaactgc
     8161 tgccggaatt gaaccagcaa ctatagctta tcatgggatt tcaaagtcta atattagagt
     8221 aggagatagt gtagttgtgt taggatgtgg tccaataggt cagtttgtta tacaatgggc
     8281 aaaggtgttt ggtgcatcta agattatagc agttgatatt tttgatgaaa aattagaact
     8341 ttctaaactt ctaggagcaa actatatact taactcaaaa gaagtaaatg taatcaaaga
     8401 aataaaaaaa ataacaaatg gtggtgctga tgttgtaata gaaactgctg gtagccgatt
     8461 tacacaagaa caatctctat ttgtagcaaa aaagagagga aatatagtgt ttgtaggtat
     8521 atcacacaca gaattaccac ttagtgcaga cgctactgag tgtatattac gtggagaact
     8581 taccttgaaa ggttcttgga attcatatac aagcccttat cctggaagag catggactgc
     8641 aacattggat tttatgggaa aaggtgacat tatttttaaa cccatgattt cacataaaat
     8701 aggtcttaat gaagtgggtg actttttaag taaaatgagc aagagagaaa ttaatttcaa
     8761 taaaatccta gtagaaatat aaaaatttaa taaaaaattc taaaagcaat taaattttat
     8821 aactatgaca ttaaataaaa taaaaataat tttcttaaat aaaatatagg aggaagaaaa
     8881 gtgttagaaa atttaaaaga agaagtatta aaagcaaact tagaattacc taagaaaaag
     8941 ctaattactt atacttgggg aaatgtaagt gggatagata gagaaaaagg attagtggtg
     9001 ataaaaccaa gtggtgtaga gtatagtaat atgactgtag aagatatggt tgtagttgat
     9061 ttagagggaa atatagttga tggcaaatta agaccttctt cagatactcc gactcatcta
     9121 gttttatata aagagtttga agaattgggg ggaatagtac atacacattc aagttgggca
     9181 acaatttggg ctcaaatagg aaaatctata ccatcttgtg gtactactca tgcagattat
     9241 ttttatggaa gtataccatg taccagaaaa atgactagag aagaaattcg caatgaatac
     9301 gaaaaggaaa ctggaaatgt aatcattgaa gaatttatgg gaagaaatcc aattcattgt
     9361 ccaggaataa ttgtaaatga ccacggacct tttacatggg gaaaagatgc aaatgaggct
     9421 gtacacaatg cagtagtttt agaagaagtc gcaaagatgg cttattatac agagttaatg
     9481 agtcctgata atattatgga taaggttctt atgaataagc atttttcaag aaaacatgga
     9541 aaaaatgcat actatggtca aaaatgatta tctggaggtg aattatgcta gactctttaa
     9601 aaggtaaagt tgtggaaata gcaattaaag cagagcatta tggtttatgt aaagaaaaga
     9661 ctggtaattt tagtattaga gataaggata ctggatatat acttataacc ccatcaggtg
     9721 taggaagaga agaattaaaa gttgaacata tttgtgtatt ggatttggat ggaaatgtaa
     9781 tagaagttga gaaaggtatt aagccaagta gtgaggtatt gatgcatatt gaaatataca
     9841 aaacaagaga aaatataaat gccatatcac atactcattc tttatatgca acagcatttt
     9901 cagtagcaaa gaaaccaatt ataccaattg tatatgaatc agttaattat ggcggttatg
     9961 tagatattgc tccatacgaa agaccaggaa ctttaaaatt agctaagagt gtttcaaaat
    10021 tactgataga tacagatgca tgcttattag aaagacatgg gttgacaact gtaggtaatg
    10081 atttagacga agcattatta aaatcaagat atgtggaaga ggtagcagaa atatactata
    10141 ggtctttagt attaaatcaa tttaaagaac ttgaagtagt agatgttgat gagtttaaat
    10201 cttggaaata cccagaagaa ataaagtttt aatctaaata attttcattg aagtggttaa
    10261 ttaaaatata tgtattattt atatcaatta ctatgtttta ttatgttaat taccgtattt
    10321 tgcaaatata tttattacat tttttcaaaa aaatatagaa tccgaaagcc atataaaatt
    10381 gacttgggat tctatacttt ttatttatgc atttttcttt atctgatttt ctggagaatt
    10441 tatatgttca aaatattttt tagtttcaga tactattata ggtgataatg caagtaaagc
    10501 tataaggtta ggtattgcca taagcccatt tacaatatca gcaattatcc aaacaacttc
    10561 taactttaag aaagcaccta ataacaccat agccacaaat acagttctat acccattcat
    10621 gccttttaca ccaaacagaa attcaaaaca tctttctcca taataactcc atcccaaaat
    10681 tgtagtaaat gcaaataatg ttaaactaac tgtaagtaat attggtccaa atgtaggaat
    10741 tgctccgtta aaagctgctt gtgtcataac agctccattt aggtctgaac accacactcc
    10801 tgaaataaca agagagaatc cagtaagagt acagattata atagtatcta taaaagtacc
    10861 tgtcatagat ataagacctt gttccgctgg ccattcagtt ttagcagcag cagcagctat
    10921 tggagcacta cctagaccag actcatttga aaatacacca cgagcgatac catttctaat
    10981 tgctagtgac atagttgctc ctaaaaaacc accagtagca gcagtaggtg taaatgcact
    11041 tttaattatt aacataaaag tttcagggat tttattccaa aaagatatta aaatgattcc
    11101 acagattaca acatatataa ctgccataaa aggtactatt ttagtagcta cattagatat
    11161 acttttaagt cctccaaata caactaaagc tacaaatact gctaatacaa cccctgtaat
    11221 tctagggtct atcccgaaac tattatttat tgcatctgtt attgaattta cttgagtaaa
    11281 agtaccgatt cctaaaagtg caactagtat accacttata gcgaaaaata ttgcaagagg
    11341 tctccatttt tctcccatac catttactat gtaatacatt ggcccaccag acacttgacc
    11401 atttttatct ttagttctgt attttattgc aagaacacct tctgaatact tagtagccat
    11461 tccaaagaat gctgctatcc acatccaaaa aagtgcacca ggtccaccag ctttgatagc
    11521 tgtagcaaca ccaacaatat taccagtacc aactgtagca gctagagcag tacataaggc
    11581 tgcaaaactt gaaacatcac cactaccttt gttttcagca gagaatatta acttaagagc
    11641 tcttggcagt ttagttattt gaacaactcc aagcttaaca gtaagtagta taccagtacc
    11701 aactaatagt accagtaggg gtggtcccca aataaaagca tcaactttgt ttaaaatatc
    11761 aattagattc ataaaaacac tccctcattt tttttgcttt acataatcaa tagaattttt
    11821 aatgaagtaa ttgacaggaa ataagtataa tttattaata atttctagtg taataaaaaa
    11881 agctaaatct aaaaaagatt cagctctgga tgtacactaa ttagcaacca aaataaaagt
    11941 attagtaaat actgtttttg gtagataatc cctgtccttt tgcctgagag attgagcata
    12001 aaagccttgc cccttcggcg cccataatgg gtctctccag agttccgtaa attttacagt
    12061 cctactttta aaagtacctg agagtgttac tccttcggtg tgctatatag caactcttct
    12121 ataaaatctt aaccggatat tgatttgtca tagcttattg tattaataat attaatataa
    12181 gtttttatgt tttgtcaact aaaaaattaa aaaacaaaga aaaaatataa aaatgtaagc
    12241 ctatttacga attataaact tagaaagatg agtaatatac gtgaaaatga attttgtaat
    12301 acacatacaa atgaagtgta aaataagttt taaataaaaa aataataaaa tcttaaataa
    12361 ttaattagat atgattaaat tatggtaata ttatagttac gatattaaga aaagttctat
    12421 ttagttagat tttaagcgta atatgagatt atgtatagag aaaggatgta tttttagatg
    12481 ggaaaaatat tagtgctagc agaaaaacct tctgttggaa gagatatagc aaaagtttta
    12541 ggatcaaaaa atgaaaaaaa tggttatata gaggggccaa agtatgtgat aacttgggca
    12601 ctaggtcatt tggttacact tgctgacccc gaaagttatg gagaaagata taaatcatgg
    12661 agcttagaag acctgccaat acttcccaag caccttaaga ctgttgtaat aaaaaagagt
    12721 ggaaagcagt ttaatacagt taaatcgcaa atgaatagaa atgatataga tgaaatagtt
    12781 atagcaacag atgcaggtcg tgaaggagaa cttgtagcaa ggtggataat agaaaaatca
    12841 caggtaaaaa aacctataaa acgtctttgg atttcttcaa gtacagacaa agcaataaaa
    12901 gacggatttg caaaattaaa aagtggaaaa gaatatgaaa atttgtatta ctcagcaata
    12961 gcacgagcag aagctgattg gattattgga ataaatgcaa ccagagcttt gacaacaaag
    13021 tacaatgcac agctttcttg tggaagagta caaactccta ctcttgcaat gttgcttaaa
    13081 agagaagaag aaataagaaa tttcaaacct aaagagtatt atggattaga attaattgct
    13141 acaaagggaa attcagatat aaaatttatt tggaatgata aaaacaataa ttcttcaact
    13201 tttagtaaag aaaagataga atccacatta aaaaaagtaa aaggtgtaga cataaaaata
    13261 tctgaagtaa acaagtcata taagaaaaaa tattcacctg cactctatga tttaacagaa
    13321 ttacaaagag atgcaaataa aatgtttgga ttttcagcaa aagaaacttt atctataatg
    13381 caaaaactgt atgaacatca taaagtactt acttatccta gaactgattc tagatattta
    13441 acatcagata ttgttggaac attaaaagat agaataaaag ctgtaaatat tagtgattat
    13501 tcaaagattt gtaatagatt attaaaaagc aatattatag ctaataaatc gtttgttgac
    13561 aattcaaagg taacagacca ccatgcaata ataccaacag aacagaaggt attcatgagt
    13621 gattttagtg ataaagagcg aaaaatatat aatcttgtag taaaaagatt tttagcagta
    13681 ctatctcctc cttttgaata tgagcagaca actataagtg caactgtaga aggagaaata
    13741 tttaaggcta agggaaacaa agtaataaat ttaggttgga aagaaagtta taaagatatt
    13801 gaagatgaag atgagtatga aagtatacca aatgttttag aaaaagatgt acttaaggtc
    13861 aagggattaa agataacttc aggaaaaaca aatccaccac catacttaaa tgagggaaca
    13921 ttattgactg ctatggaaaa gaatggtcta gggacagttg ctacaagagc agatataata
    13981 gaaaaattat tcaattcatt tttaatggaa aagaaaaata aagatatata tataacatca
    14041 aaaggaagac aattattaga tttagttcca gtagacttaa agacaccaga acttacagct
    14101 tcatgggaaa agaaattatt ggatatttca aagggaaaac ttagtaaaaa tacattcata
    14161 aatgacatga aagattattc aaaagatatt gtactagaag taaaaaatag tgataataaa
    14221 tttaaacatg ataacttaac taaaaataga tgtccagaat gtggaaaatt tatgttagag
    14281 gtaaatggta aaaaaggtaa gatgttgatt tgtgaagata gagaatgtaa tactagaaaa
    14341 actatatcac aagtaaccaa ttcaagatgt cctaactgtc ataaaaaatt agaacttcgt
    14401 ggagaaggtg aggggagaat cttcacttgt agttgcggat acagagaaaa gttgtcttct
    14461 ttcaacaaga gaaagcaaga agaaaaacag aaggcatcaa aaaaagatgt taatcaatat
    14521 ttaaaaaatc aaaataaaaa tcaagagaca tttaataatc catttgcaga agcattagct
    14581 aagctaaaaa acaaataatt ttaaagttat tattatacac aattataact ttaactgtat
    14641 attagttata tgtactgata taatatagtg tatagtttag gcatgaaagt agggctgtta
    14701 aatggattta agtggcatat ttaaatacta ttgtaaagag tgtgaaaata catggaataa
    14761 ttcgagtgtt gaattatttg agaatataga aacgtatagt aaagattcac aaaaaaagag
    14821 ggaaaaagaa ttagataaat tgctaaatac aatatcagtt catttagaga ggtatccaag
    14881 tgatgctgta ttgagaaaaa tgtgggtaaa aaagggcgag gttttcttac aaaagacatt
    14941 ggaaaaagaa aatattttta agttagaaaa aatggatgta gaggatagaa aaaaattttt
    15001 agatataaca aaacagttta ttagagatgc tagaaaattt gatgatgatt tacctatagg
    15061 tgatattatg caagctatga ggaatgtatg gatttcaaat gcattacaat tattatttgg
    15121 taaagaagta tattattcaa aagctaactt tgcatatagt atgttatatc catatactga
    15181 taattattta gacaatacaa atatagataa aaatgataag attttattta ataactggtt
    15241 agaaaaaagg ctcctgggag aacacattaa atctaaggat tatcatgaaa gtaaagtatc
    15301 tcaaatgata gattatattg aaagtgtata ccctagagaa aagtttacag aagtttatga
    15361 atcgttatta ttaatattta aaagtcaagt aaatagttta aaacaacatg gtaaggaaaa
    15421 tcatttgtgt aaagaagatt tattatccat ttctattgaa aaaggaggtt catccgtttt
    15481 agtagatgga tatttaataa gtggattgat gacaaaggaa gaaatagagt tttgtatagg
    15541 atatggattt ttattacaaa tatctgatga tttacaagat ataaaagaag atttaaaata
    15601 caaccataaa actattatta cagagatgtc aaaagagggt actttagata aagttgtaaa
    15661 taaactaata aattttacta ttgagttaat agatagtttt aaaattaata ataaaaataa
    15721 atctgtaata actatgataa agaatgattg cttaatgtta attttatttt ctgtagttta
    15781 taatgctgaa tttttttctg taggatatat aaaagaagta gagaaattta ttccatatac
    15841 aatagattat tcattagaga ttgaagaaaa aataaaagaa aaatttaaaa atatagatgt
    15901 tttaaataat gaaaatgaat ataaagaaat gattgatatt atttgtgcag agtagaaaaa
    15961 aagggagtgt cttagaatag actttttagt ttatgaggca ctctttttgt ataaaatcaa
    16021 atgtattttc atcattttaa caattaaaaa gaacttatcc ctatttgaga aagccctttt
    16081 taatttaaat aaaaatgtca aggttaaact atttaaatgc agtaataatc ccattatcat
    16141 gtaagttttt tatgattgta gctgcgatag ggaatccaaa taatccagct attccaaata
    16201 gttgagcccc aacaaacata cacattaatg ttattaaagg atataggcca atttggtgtc
    16261 ctactacctt tggttctaat atttgtctaa caacggttat aattatgtat agtattaaaa
    16321 gtcctattgc taaattaata tttccattaa tgagtgagat aatcatccaa ggtgtcaaaa
    16381 tacttcctgt acccaagact ggcaaaatat caacaagtgc tatgatgaca gatatagtaa
    16441 atgcattttc aacctttagg atagtaagtc caataagtag ttctatgaat gtcactgata
    16501 gtagtattgc ataggctttt agtagtttta aaagagcatt aatactgcta ttttttatat
    16561 ttattatcat aaattgactt ttttctggaa attgttttaa gataaagttt actatttttt
    16621 gatagtcaaa agtaaagaaa aaagaagcaa ttaaagtaat aataagtttt aacataaatg
    16681 caggtgtttt acttgcaata ctagcaatag cattgagtgc atttgttgaa atagaagcta
    16741 ctaaagacat catagattga cttatattat cccaaccaag tattaatgct aggttaacat
    16801 taggtgtact agcatctatc tttgaaaata aagtatttag cgttggttgt atacttgatt
    16861 tatatatttc aggaagtcta aaaaatacat cacttacact tgcaaatatc ttcacaccaa
    16921 agctaactaa taaaaatata cacaacccat aaaaaattaa aagtattact atagaaataa
    16981 gtgtacgatt taaatttgta ttatttgtaa taagtcttat aataggtctt aagatggatg
    17041 caatgataaa actgattaca aaaggcatta ataatggcaa taagaatttt aatacaatat
    17101 atacaatact tgttattaaa actacatatg taaatttaat tataaaattc ttttgctttt
    17161 gaatatccat aatataaaac ctccaatgta tttgatatta ttctaaatat ggtctttttt
    17221 acagaaaata tactactgta tattgattat aaactataaa gcttatgtaa agtaaataaa
    17281 ttatgtaaaa tttaggttaa ttttgtataa agagatactt ttatatttta caattaataa
    17341 ccaaatacta aaaaatattt taaataaaga acttaaaatt gtgataaaat taatttatag
    17401 atattaaaaa aagtataata tatggttttt aagaggtgct aagatgaaaa attttagaga
    17461 tttaggtggg aacaaaactg aggatggcag aactgtaaag aagggattat tttataggtc
    17521 tgcaaaatta tcaaatctaa gtgaaaatga tataaaaatt ttaagagagt taaatattaa
    17581 atatatattt gattatagaa gtgatgaaga agctcgtaaa catccatcaa caataatatc
    17641 aaatataaaa aatataagaa taccagcaat gagagagcta gaagaatcag gaggaagttt
    17701 tggttctatt gaagatatga ttgatggatt gtttgaaaaa gatggtgcat ttaatatgtt
    17761 aaataatagt tactataatt tgcctataaa taatccgtca tataaaaaat tagtagaact
    17821 tataagagac tattctaatt taccaatatt aaatcattgt acagctggta aggatagaac
    17881 tggtgtgggg agtgctataa ttcttatgat tttaggggta tcgagagaga atataatgaa
    17941 agattatcta aaaagtaatg attttgcaga taaagagata gaaagattta tagaatataa
    18001 gcctaaattt aaggacattc caaaagaaaa tttgaaatat atatttggtg taaatgaaga
    18061 gtatatgaaa actgcattta gaagaattga tgaagaatac attagtgtag aagcatattt
    18121 atatggagaa tttaatttaa ataaagaaga aataagaaaa ttaagaaatc aatatctaga
    18181 gtaaaaggtg agtttatgag tttaaatata acagcaagac agataaatat aataaaaata
    18241 ttgttaaatt caaaagatac aattagtggt attgccttaa gtcaagagat aggatgttct
    18301 tcaaaaacta tacaaaatga aataaaggat attaataaac aacttagaaa tggtaaaatt
    18361 ttgtcaataa gaggagttgg ttataaacta gaaggaagtt ttgatgaggt aaatctaaat
    18421 agcaatctct atgatgatgt agatagagta gaatatataa tcagaaaaat attaacctta
    18481 agtaatgaag aaaaaaatac tataaaactt gaagatttag ccgattctat gtatgtaagt
    18541 gtttcaacag taaaaaatga tttaaaagaa gtaaaaagaa tgttggaaaa gtattcaata
    18601 tcagttaaat ctaagcataa acaaggtata tgtgttttgg aaagtgaaga taagatatta
    18661 aattgtatag ttgacttaag caataagaga gataatcaat tgagtttaaa tgatttttta
    18721 aatgatgata taaaggaaag aaaactatta ataaaaaaat tattattaga catattaaat
    18781 gaaaatggat tagtattaac tgatatagaa tttaagagtg tgttaaataa tatattagtt
    18841 atgttaagca gacataagta taatgaaaaa gaatttatag agaattatat agaaaattat
    18901 aggagcaaaa gaagctcaat tttagaaaat gaacaaaaca aagaaattat aataaattca
    18961 ataaaaacat tttgtaaaaa tttaaaatta gctacatcaa tagatataag taatgataag
    19021 gtatttgaag agtttttata taagcatatt agtagtttat gtaaaaaaat aaagttaggt
    19081 ataaatcaat cacctataat ggctcaagat ataaaaataa aatatccatt tgcttttgaa
    19141 ctagctaata tagctaaaaa gacaatagaa aaagatttga agatagaaat taatgaagat
    19201 gaagttgcaa acatagctct acatatagga ggagcagttg aaagagcatc ttataataat
    19261 aaagataagg ttttcaaaac tataatagtt tgtacttcag gcataggcac atcaatgtta
    19321 ataaaagcta aattagagaa tatatttaag gaaaaattag aaatactaaa gattattcct
    19381 tcatacttag ttgaatatat aaaagttata gatgttgatt ttgtaatatc tactgttcct
    19441 attgaagtag gagatgtgcc agtaataaat atatctccaa ttttaagtga gaaagaaatt
    19501 agattaattg aaaaatatat agaaacagga aatatatacc tagatttaga tataaaaagc
    19561 ctgtttgata gtgaattgtt ttttactgat ttggtgttta aaaggaaaga agaagttata
    19621 gattttatgg caagtaaact tgtacaaaag ggctatatag atgaggatat gaaaaaatct
    19681 tactttgaga gagaaaaaat agcaacaaca gaaataggga atatggtaac tataccacat
    19741 ggagctattg gaaaaatttt tgataataaa atagcaattg gtatattaaa gaagcctatt
    19801 tcttgggaaa tatcagatgt tcgtttaata ataatgttag cccttgataa agataaaata
    19861 ttagattatg aagtaatatt ttcaaaaata tataaaagag tagattctat agcaaaagtt
    19921 ataagtatat gtgaaaatag tagttttgaa aaatttgtaa atttatttaa ttagatgggt
    19981 agtattgtat atacacctgt aaatttggat aatataaaac taaataagat aaaaacgata
    20041 aatttctctt ttaattaaga gaaatttttt gactttcaag gatattaata taaagttaag
    20101 atataaacat aaagcaaata aataaaaaag aggtggcaat atgatttata cagtgacatt
    20161 aaatccatca atagattata tagttaagct agatgagcta aagacaggaa gtacaaatcg
    20221 tgtaaaagaa gaatacgttt atccaggagg aaaaggtata aatgtatctc gcatacttaa
    20281 ggaacttgga aatgataata catctttagg ttttataagt ggttttactg gagaatatat
    20341 aataagaaca ttggaagaaa aagaattgaa gacagatttt ataaagataa aaagtggttt
    20401 ttcaagaata aatgtaaaaa taaaggcgtt aaaggaaact gagattaatg gacaaggtcc
    20461 aaatatagat gatgaagaca ttgatacttt atataaaaaa cttgataagc taaatcaaga
    20521 tgatatttta atattggcag gaagtatacc atctacttta gatgaaaaac tatacgaaaa
    20581 tataatggct agattagaaa aaaagaatat aaaagttgta gtagatgcaa ctaaaaatct
    20641 tcttcttaat gttttaaaat ataaaccttt tctaattaag cctaataacg acgaattaga
    20701 agaactattt ggtgttaaat taaattcaat tgaagacatg gtaaaatatg ctagaaggtt
    20761 aaaggaaatg ggagctataa atgtcttggt atcaatggga aaagatggag cattgttgat
    20821 tacagaggaa gatgaagtgc ttataagtga tgttccaaaa ggaaaagtaa aaaattctgt
    20881 aggagcaggt gattcaatgg tagcaggatt tatatctggg tatttgaata ctgggaaata
    20941 tgattatgct cttaaattgg gagcagcttc aggtagtgca actgcttttt catatgactt
    21001 agccaaaaga gaatacattg ataaattggt aaatgagata tctgtaaagc agttttaaaa
    21061 tattaaaaaa tatatagaaa ggtaattaat atttatgaaa attatagatt tattagatga
    21121 aaagtcaatt aagttaaatt taaattcaaa aaccaaatca gaagcaatag aagaattagt
    21181 agatttggtc gcaaatagtg gaaatttaaa tgataaagaa aactacaaaa aagcaatttt
    21241 ggctcgtgaa gaaatgagta caacaggaat tggagaaggt gtagctatac ctcatgctaa
    21301 aaattcttca gttactaaag cttgtatagc agcagcagtg tcaaaagaag gtatagatta
    21361 tgaatcgttt gacggaagtt tatcaaatct attttttatg atagctgcac cagacggagc
    21421 taacaatact catcttgaag tattatcaag attatctaca atacttatgg atgaagactt
    21481 tagaaataaa cttataaatt caagctctga aaaagaattt aaggaaataa tagataaaaa
    21541 ggaaagagaa aaattcagtg aagaatatca agatgagaaa gttactgaaa aaaatataat
    21601 agatactaaa gagaatgatg ctaataagta tcctaaggtt ttagcagtaa cagcatgtcc
    21661 aactggaata gcacatacat ttatggcagc tgaaagttta aataaaatgg cagaaaacaa
    21721 aggtgtatca ataaaagtag aaactaatgg ttcagcaggt gttaaaaata agcttacaaa
    21781 agatgaaata gaaaatgcaa catgtataat agtggcggca gataaaaatg ttgagatggc
    21841 tagatttaat ggtaaaaaag tcataaaaac taaggtggct gatggtatac acaaagcgga
    21901 agaacttata gacaaggctg taaatggaga tgctccaatt taccatggag gagatggaag
    21961 tcacaacgaa tcaaatgaag aaagtgaaag tggatttaga aaagtataca aacacttaat
    22021 gaatggtgta tctaatatgt taccatttgt tattggtgga gggatactta tagcgatagc
    22081 ctttttactt gatgattata ctattaaccc ttcaaacttt ggttcaaata cacctatagc
    22141 agcatttttt aaaggaatag gagataaagc ttttggattt atgttacctg tacttgctgg
    22201 atatatagca tactctatat ctgatagacc agcgtttgtt gtaggatttg taggaggtgc
    22261 tctagcaggt gatggtggtt caggtttttt aggtgcacta cttgcaggtt ttatagcagg
    22321 ttatttagta gaagggctta agaaaatatt tagtgtacta ccagcttcat tggaaggaat
    22381 aaaaccagta ttgttatacc ctttacttgg aacacttttg atgggaatta taatgacatt
    22441 tttagtaata cctccagtta cagcaattaa taatgcaatg gttggatttt taaatggttt
    22501 aggtggaact tcaaaaatag ttttaggatt agtattaggt ggaatgatgg ctgtggatat
    22561 gggtggacct gtaaataaag cagcatatgt atttggagtt gcatcacttg aatcagggca
    22621 gtttgaaata atggcagcag taatggctgg tggtatggtt ccgccacttg ctatagctct
    22681 tgcaactaca ttttttaaga atagatttac taaagaagaa agagattctg gtaaagttaa
    22741 ttatgtaatg ggattatcat ttgttactga aggagctata ccttttgcag ctggagaccc
    22801 acttcatgtt ataccagctt gtgttggagg ttcagcagtg gcaggagcac ttagtatgtt
    22861 gttcaacgca gctcttcgtg cacctcatgg aggagtattt gttataccag tggttaccca
    22921 tccatttgca tatatattag ctatagctgt aggtgctttg gttggaatga tgcttttagc
    22981 attacttaaa aaaccattaa atcaagaagt atagcaatta aaggatattc aagaacttaa
    23041 aatatgatgt tttataaaaa ttaatatatt gctgaattat tttaaaataa ggattttatg
    23101 aggctgttat ataacgattt gtaattgtta tcttgacagt cttttatttt tatataagta
    23161 aaataagtgt gttttgcttt atttgtattt aaattgtttt taagttagaa tataaagaaa
    23221 attatatatt attttaatat tcactcgaac tagaaaataa tatttgttgt atttttttgt
    23281 atataaaata tattgtaata ttaaaaaaat aatagtaaac tgattgcata aaaatgattt
    23341 ttatataaaa tttaagcaga agaataaatt tctaacgaaa ttggatattt cttctgtaaa
    23401 tacatattca aaaaaagaat tataagagtt tagtcagcag tcgtgtaagt aataaggact
    23461 ttataaatat atagaaatat aatgatatta atataaccaa gcgattttta atttagcttt
    23521 ttaataagct tattttttat actatttata ataaataaac tccatgatgg gaaaactatt
    23581 actatttaat atgtaaagga gtattttaaa tgaatgaatc atattggttt ttaaactcaa
    23641 gtccaaaaga atataacaaa ttaggtgaaa atataaaaac agattgtctt atagtaggtg
    23701 gtggaataac gggattgaca actgcatatt tattagcaaa agaaggtaaa aaagtagtgc
    23761 ttgttgaggc tgataaaata ggatatggaa cttctggaag gaatactggt aaggtaactt
    23821 gtcagcatga tatattttac tctaagatag agaaaaaata tggattagat aaagcaaaat
    23881 catattataa tgcaaataat gaagctttaa atttagttga acaaataata gaagaaaaca
    23941 atataaaatg tgattttaaa agggaaactt cttttgtatt tacagaaaaa gaggatacta
    24001 taaaggatat taaagatgaa tatcgtacat gtaaaaaaat aggaataaat tgtgagtatc
    24061 atgaaactat agaaaatatt ccattagata taaagggggc tattagtttt actaatcaag
    24121 gtcaatttaa cccaaagaag tatattgatg gattggcaaa agcagcagta aatttagggc
    24181 taaaaatata tgaaaataca ccagtagtag accttgaaaa aggaaaaata tgtagggtta
    24241 aaacaagaga ggataatata atagaagctg agaatgttat aatttcatct catagtccat
    24301 ggtatgatgg attgaatttt tattttgcaa aagaatatgc agagcgtgct tatttaatgg
    24361 ttgcagtttt ggaaaataaa ttagcagatg gtatgtttat aagtatagat gacccatcaa
    24421 taacttttag acaatataat gatggaagtg aaaatttact gatttttgga ggaggagacc
    24481 ataaagttgg tcagggagga actgagaaag aaatatttga tgatttagag cattatggta
    24541 aagaagtctt taaggtaaaa gattttaagg ggaaatggtc tgctcaagat aatatgagtt
    24601 ttgacaatgt tccttatatt ggttatatca acaaaagaga agacaatatt tatgtagcta
    24661 cagggttctc taaatgggga attactaatg gaactgctgc tggaataata ataaaagatt
    24721 taataataaa taataattct gattataaag atacttttaa tccatccaga ctaggtagct
    24781 acttttcaaa agattttata aaggaaaatg caaacgtagc aataaattat gtaagtggaa
    24841 aattaaaaat aggtagtgga gatatgccta aaaataatgg agaaggaaag attgttaata
    24901 ttgatggaaa aagatatggt gtatataagg atgataatgg agatttttat attgtagaca
    24961 ctacatgtac tcatttagga tgtgaactta attttaacag tgaagaaaaa acatgggact
    25021 gtccatgtca tggttctaga tttgactata agggaaatat acttgaagga ccagctctta
    25081 agccattaaa actttatgga catggtgata atgatgttaa tcctaagtta ttataaaatt
    25141 atttttagga aggtaaagtg tatatgaata aacttttaaa gccaataact atactattgt
    25201 atatagttta tattttatct gccgtatttt ttgtagcaaa caaagaatat ggaagtctag
    25261 gtctagtagc aattagttta gttggtactt tcattttgag ttttataaat aagcaaactg
    25321 aaagattatt gagtaaagaa ttatatataa tgcttgcttt atttataatg ttttcatcat
    25381 tgttaggtac ttgttttaat ttttatgata taaattatta tgatgatttt ttgcatttat
    25441 ggtcaggtat aatatcttgt attgtggctt tttctataat taaatacttt tatacacaaa
    25501 gagagataag taaaatgagt aaagtgtttt tagttatatt tttatttatg tttagtatgg
    25561 gagtagcgag tttatgggaa ataggtgaat ttttaatgga tacttttgtt gggactacta
    25621 cacaggccgg agggttagaa gatactatga ttgatatggt agatgcttta ataggcacaa
    25681 ttataactat tccttttata gtaaaaaaat ctaatatata gttttaaatt ttttatatta
    25741 attataatgg atttaattaa tcatgttgag tttcaaggtc tatatgatta attaaatcca
    25801 tttttgttat ttataattat tattgaatat atttttacat ataagatata aggtgataga
    25861 tagaaattgt tggattatgt aaataattaa tatataatac cattatgggc aataaataca
    25921 aatcaaatga taatatagtc tatttatgta aatgttatat tgtatcctaa gtataatagt
    25981 aagttttttg atagtggtgt agaaagtaaa aatctactag cctaaattga tgtatggatt
    26041 agtttaggaa cagtaattgc atatcttaag tttgatgtca tgttgggcta ctagaaatag
    26101 gtcatctttt tcacttgaat atcttttctt taaacatggg gagtatcata tcaaaaacat
    26161 atgaaaatta agtgatttat gagaacagta atattttata tgatagtata gaatagtaat
    26221 aaagtattag gaggaacatt gagtgttaaa aaagtggttt ggtattgtga aaaaaagaca
    26281 aaaaagtgag tcagtaaaag aagaaggtga agtaatatta aaaaacgaaa aaatattatc
    26341 tgaagaaaag ttgatagatg aagaaggagt tgtagttaat attgataatc aaatattaac
    26401 taaagtagta aatgatgaca atgaaataga agaaaaaata atagaagaag atttgttaat
    26461 tagtgaaaat accataaaat tagatgataa agaagcaatt attaatgata aaaacataga
    26521 attatgtaaa aaagaagttc aagttgaaag tgaaaaaata ggtttaaata agtttgaagg
    26581 actggaccaa aatgaaaatt ataatctaga aaaaaatgtt attgaagaaa aaaaagtaag
    26641 tgaatgtttg acagaagaag atttagagta cataaaagaa attaaaataa aaagaggaaa
    26701 aagtataaaa gctataaact tgtatactaa agaagagtgg gtttttgaca ctcatataca
    26761 gtgtagtaaa aaactcaaag ttccattagg gtacataaga gaaaatttaa aatatggata
    26821 tatggattac tttggagatg caataaatta tttaagtgaa gtattaaata tagatgaata
    26881 ctgcaaaagt gaatggagct atctcgataa tagcaaatct ccatctgaga tatttaatat
    26941 tctaaacaat aaaatattta gtataaggct ttctaatgaa aaaagaaatg aaattttgac
    27001 aaatgataaa attgaagcat taaaaatgaa ttatagattt gaatgtattg atgaagaata
    27061 tgatgaatat tttaaaaaat ataagtctat aatcaaaaga ggtggaaaga aaaaagttga
    27121 attagtaaat aaaaaaggtg acattttaga aatatttaag tctttagaag aatgtgccat
    27181 ttatttgcaa aaggaaaaga atgaagttat acaaatgtta aaatatggag atacaaaagt
    27241 aggaagaaac tttataaggt atagtttgag aagtatttaa tttcatttta aattcataag
    27301 agtttcattt ctgattcaca catttaatat tattttaatg taaaataata aaggtgaagt
    27361 attgcacaat taaaattaag gagggtatta atgtctgaag aaaaaaatcc aaaagaaaat
    27421 acattagatg aatctaaaaa ttcagataat gtaaattcta aaaaagatga tgtgtcagat
    27481 gaaaaaaata ctgataacaa agttaaaaaa agggaaataa agctaaacaa caaaacactt
    27541 aaagctattg tagcaattgt tgcagtagga gctatatgtt taggtggagg ctatgttttt
    27601 ggcaaagaag ctggaagaaa attgcctgct acttcaaaac actataatag cagtgaggta
    27661 gtagctacta ttggggataa aaaaataaca ggtgaaatgt taagaaagag aatggagcca
    27721 ttattttatt taaatgcaaa aactactatg actgatgacg aaatacgttc atatgaatca
    27781 aatatgattg aaactatgat tacatctgat atattatcct ctgaagcagc aaaagagaaa
    27841 ataagtataa ctaatgacca actagatgct cagtataata atttaatgag tagtatagaa
    27901 tcagcaatgg gaatgactaa agaagagttt ttaaaacagt ttgatttgac tgaaaaatat
    27961 ataaaagatg atatgaaaaa agagctagta gcatcaaaat atttaaatga aaaatcaaaa
    28021 gttactgata aagaagcaga gaactattac aataaaaaca agagcaatta tttacaagtt
    28081 agagcttcac atattttaat aaaaactgtt gatgataaag gtaagcaagt tagtagtagc
    28141 aaaaaagctg aacttaagaa agaagctgaa gaaatactta aaaaagccca agctggggaa
    28201 gattttgcta ctctagctaa aaaatactct gaagatagta gtgcagaatc aggtggagat
    28261 ttaggtttct ttggtaaagg tcagatggtg gaatcttttg aaaaagcagc ctttgcattg
    28321 aagaagggag aggtatctaa caaacttgta gaaagtgatt atggatatca tataattaag
    28381 aaaactgatg aaaaatatca gccatttgaa gaggtaaaat cagatttagt aagcagttta
    28441 acatcagaaa aacaaaacct acttatacaa aatctaaaag aaaaatataa tgttaaaatt
    28501 acagataaat atcaaatgaa agctaaagaa tagataaagt caatttatta aaaaaaagaa
    28561 aaattaactg tatggataaa agctattttt actctcaata tagaga
//
LOCUS       DAMKNB010000045        27808 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.047, whole genome shotgun sequence.
ACCESSION   DAMKNB010000045 DAMKNB010000000
VERSION     DAMKNB010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 27808)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27808)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27808
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.047"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            complement(101..1288)
                     /locus_tag="PC494_002204"
     CDS             complement(101..1288)
                     /locus_tag="PC494_002204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3798 domain-containing protein"
                     /protein_id="HDF3912703.1"
                     /translation="MLRKITAFMLSICLIIGLTGCSLLVGKKDKEKIIDDFKVAVVTQ
                     PLSENKVQYNMVEEMAKEYEEENKIDKDKDGQTKVKQTIKHVVLPENFTSNIDSAINK
                     IVKLADDKEVQAIVVSTDQAGLLPALQKVKEKRPEIITISAPMGDDKNQLSQFVDVNL
                     GVSAEERGKVLAERSKEMGAKAFIHYASTDDLKDVNIAKRLEMIKETCKNIGLPFVQV
                     NTPNINTEEDKNKVKQFLNEDIEKQVKKYGKDINVFGVNEYMDEVILTKALELKYIVA
                     EQSNPSPIQTYPSVMGLKISEKDAQNYDKINDMISEKAKAFGMSNRLGGYPMPMDAFL
                     PSVAIYLATEMVKQDLTQEDVCDPDYLEAFTELRFGIGSEFTPLTEVLYNYQSVILSQ
                     LIY"
     gene            complement(1490..2761)
                     /gene="brnQ"
                     /locus_tag="PC494_002205"
     CDS             complement(1490..2761)
                     /gene="brnQ"
                     /locus_tag="PC494_002205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004455013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HDF3912704.1"
                     /translation="MRDIFIVGFALFSMFFGAGNLMFPPFLGMESGKDWLIPLIGFVV
                     ADAGIAMLVIIATARCKGSMDDVLRRAGKGLARVMSVAALACLALLVIPRTCATTYEM
                     GIMPIFGDHGPVAKAVFSIIFFGLTLAFTIRSSKVIDIIGKYLTPALLLVLFVLIVKG
                     IISPAGPMSPEHMIDKNLFGEGISQGYQTMDALGAASMATIMLMSIIAKGYTSDKDQI
                     GMTIKAGFVACVFLAVVYGGLTYLGATVSTLYDTSIPQASLLVEITSILLYGQVGKVI
                     LGVIVALACLTTSTGLTASISTYFEGISKASYKQLVIGICVASMLISNLGVDSIIAIS
                     VPILQTIYPVLLAIVVMELAGKHIKNDNAFKGAAYVTLVISLLSAINGMTGAVPFIQS
                     LPLAGLGFNWVIPAILGGIVGNFIKSNKQVA"
     gene            complement(2902..3555)
                     /locus_tag="PC494_002206"
     CDS             complement(2902..3555)
                     /locus_tag="PC494_002206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HDF3912705.1"
                     /translation="MTKIIKVQKPKFTGELEIIENLEDILEDIFNDEKIFNKIIENEV
                     ISDLDSVRVSFESCIFRNVSFENCNLKKIDLLDVVFENCNLSNTFFDGGSIYRVEFKN
                     SKLIGVRFDDCILKNVLFKDVLGKYSNFSFSKFKIVSILDSNFENSVFQEVKGDNLVF
                     EYTNLKKANFNGTKLSGIDFTTNNIEGIEIGIDDIRGAIFDVSQAIDLTKLMGIIIK"
     regulatory      3884..3985
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            4058..5401
                     /locus_tag="PC494_002207"
     CDS             4058..5401
                     /locus_tag="PC494_002207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HDF3912706.1"
                     /translation="MVPNTNNVQPGGNNSSLSFLDKMFKFSERGSSLKTEVIGGVTTF
                     LTMAYIVFVNPAILSEAGMDKAALITVTILATAIGTLIFAILGNAPFALAPGMGLNAF
                     FTYSLVIGAGIPWQTGLGVVFLSGCVFFTLAVTGLRKTIADAIPRELAVASSAGIGLF
                     LAFVGLKNMGVIIANPDTIVSLADFTPTVLIALFALILMAILEYKKVKGGILISIVVA
                     TIISVIFGFVELPTAIISTPPSIAPVAFKLDIVGALKFSLIGPIFSFMFIDMFDSLAF
                     LITCCKQMGLEDENGEIKDLGRMLYADVSSTLIGSFLGTSTVTTFGESASGIAAGART
                     GLASIVTAALFLATLIFTPLLGIVPTYAAAPALVMVGVFMFESIKQIDFADSKIAVPA
                     FVTVLLMPLTYSISIGLCFGFISYIIMHVVAKETDKISITLWIIGLLAVVNLVLS"
     gene            5580..6944
                     /locus_tag="PC494_002208"
     CDS             5580..6944
                     /locus_tag="PC494_002208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HDF3912707.1"
                     /translation="MSQLLIKNAYLITMNADREVYENGSILIENNIIKEVGKFDINIV
                     DKDAEIYDAKGKILMPGLVNTHVHLSQQLGRGLADDVVLLTWLRERIWPYESSFNYED
                     SLISSTACCVELIKSGVTTFLESGGQYVDAMVEAVDKTGLRACLAKSVMDTGDGLPEA
                     WQKTTDEEINTQLDLFHKFNNTSNERIKIWFALRTIFNTTEELLVRTKELADKYNTGI
                     HMHIAEIADEISFVKQNNGVGTVEYLDKLGVLGPNLLAAHTVWLTHKEIDLFRLHDVK
                     VSHDPGSAMKVVLGFASIPEMLEKGIPVSIGTDGAPSNNRMDLMRDMYLTSLIHKGRT
                     LNPTVVPAEEVLEMATINGAKCALLEKEIGSLEVGKKADMIILNPDTIHCLPMHNPIG
                     NIVYSMTSENVDSTICDGKWLMKERKVLVVDESELLNKVKKQASKIKDKAEVKIPSKF
                     KIIK"
     gene            complement(7122..8987)
                     /locus_tag="PC494_002209"
     CDS             complement(7122..8987)
                     /locus_tag="PC494_002209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIRAN domain-containing protein"
                     /protein_id="HDF3912708.1"
                     /translation="MENVFKRLQEFNGYDGYKESFEMNYLCIYESIPLREQVELANNL
                     VDEILNMYKSESNEIYLLEGSNSKSLICYFEIFMKKINTLVKEMIIDEKWLYKLTKEL
                     IYKSKKVEYVKLGLVLSEKYLNVENLREVVDTFSKSGEYVFYLSNTIKKLEFYNTYLF
                     NLSKKATGSIKVFAIVNMENLDSKINSYLIEDGYKDTKYERLLMNYIISIVDLNEYLE
                     KRDLDKEKINNLARLICNYLLSVEFKYIGNKLELVNRFLPTVVNYGTNFESLYSIFLI
                     AINVLKDENIECNKIEFEKEINGILLSEKWKNIYFEALRDASGKTEDIIKMSEIYDVN
                     LSFDDLLPYLNRDIRDFEVYWHISKKGTTSSRLKLLNFFEETFKIDDLIGKMKDIEKD
                     KLTQEYYDDMLFFIVLKGSKSLYPEGKNISLKGIFGNINEVRKESINILKRYREKLSL
                     EELKIVKEAYEKEKNVILKDELRRVLYESNNLKKEFVNIEKIKVDEHGKDIYLTSIAV
                     AGSRFRNREYLEKELEKSKIYYLTREKDNLYDEKAIKIVGETGYVIGYVPRKENYILS
                     NLLDGGKLLYCRVTEYNLYEDCIYANVYLSYKDVIETVENSLKMVLDKSRIKLIN"
     gene            complement(9223..10440)
                     /locus_tag="PC494_002210"
     CDS             complement(9223..10440)
                     /locus_tag="PC494_002210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004455016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDF3912709.1"
                     /translation="MNNKKYYPTAIALYFSYFLLGIGISILGQYKPEFSSMWGAKTLS
                     DGTLDVSIVLAVIAALGLGRLISYPFAGPISDKYGRKVSGLIGNFLHAIFFVGIVFSP
                     NFYIAYVFAIIGGAANSFLDTCVTPSCMEIFASLGTIANMFTKFTIALAQFLLPFIIG
                     FVAANSISFKVIFIVTAILIVVDAFLIAVLPFPPANNVIDNKGKTVKSEKMKFTPTSI
                     ALVCIGFTCTSTFVLWLNCNQELGKLYGMADPTKIQSFYSMGVICAVLITSLLIKKYI
                     KPIRILVIYPIIALLMLLVVYFVQTPTICMLGGFVIGYSAAGGVLQLTTSTANEMFPT
                     NKGKITSIVMIASSIANYVILNIAGIITKSGGVNGPKYVVLFNVAITFVGILLALFVN
                     MRYEKEKVYDYDV"
     gene            complement(10640..11503)
                     /gene="aroE"
                     /locus_tag="PC494_002211"
     CDS             complement(10640..11503)
                     /gene="aroE"
                     /locus_tag="PC494_002211"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004455017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HDF3912710.1"
                     /translation="MEISGRTGLFALIGTPVGHSKSPVMYNYSFKKLDLDYRYLAFDI
                     TVDKVKEALLAIKTFNIKGANVTMPCKSAVTEYMDELSPAARIIGACNTIVNDNGKLV
                     GHITDGVGYVRNLKENGVEVKGKKITIMGAGGAATAIQVQCALDGAREISIFNPKDDF
                     YKRAEQTVENIKKDVPECVVNLYDLEDTNKLYEEIQSSDILTNATLIGMKPYDNETNI
                     KDTSVLRKDLVVTDVVYNPKKTKMIEDAEANGCKAIGGLGMLLYQGAEAFNLYTGLEM
                     PVEEVNELCFK"
     gene            complement(11585..13507)
                     /locus_tag="PC494_002212"
     CDS             complement(11585..13507)
                     /locus_tag="PC494_002212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HDF3912711.1"
                     /translation="MKISSMFTPIRIGSMTVPNRFVVPPMGNNFANTDGTLSETSKAY
                     YLERALGGFGLITIESSVVDKKAKGGPRKPCLYDDSTIDSFKNVIDACHDAGSKVSIQ
                     LQHAGSEGNEKVAGHPLKAASAIPASNGRNTPLAITTEEIYELIESYGDAALRAQKAG
                     ADAVEVHCAHGYLVSSFISQRTNKRVDEFGGCFENRMRLPRLIIENIRKKVGNSLAIL
                     CRINSTDDVPGGIDVHDSSVIAAYLEDCGIDGLHVSRSIHIHDEYMWAPTTLHAGFSA
                     ELVTEIKKAVSIPVITVGRYTEPQFAELMVRQGRCDLVAFGRQSLADPEMPNKAKNGK
                     LDEMIPCIACLQGCVPNMFQGKPIACLANPILGHEAELKPAEISKEVLVVGGGVGGML
                     AAWVCAKRGHNVTLVEKSEVLGGQMRLAAYPPGKGDITNLVRSYISKCNQYGVKICTN
                     TEATVELIKEKSPDVVIIATGATPLVLPIPGINDSGLIHAVDLLDGKKSCGKKVLVVG
                     GGMVGCEVAAFLGEQEHEVTVIELREEVGADVISEHRKFLMNDFENYNIHTITGAKVS
                     KFYDDGVDYLLTDGTEHDLKGFDSVVLAMGSRNYDPLSEVIKEVVKETYIVGDAVKAR
                     RALDATKEAFEVALNI"
     gene            complement(13586..14434)
                     /locus_tag="PC494_002213"
     CDS             complement(13586..14434)
                     /locus_tag="PC494_002213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HDF3912712.1"
                     /translation="MNNQKNLNIPITISSYTLGTEVSFRDRVRIAKEAGFDGIGLRAE
                     NYIDAKNAGVTDEEMIAILNEYDMKVTEVEYITQWGREEDRTEAQREKEQNVYHMAHL
                     FNVKHINCGLLEMIPEEQIITALGELCDRAGELIIGLEFMPYSGVPDLATAWRVVKGC
                     NRENAMLILDTWHWARAKQTAEDLAPVPADKIVSIQVCDVLETPYEKLRDESLHDRLA
                     PGEGYGNTEEFVKIIKEHNISPRVIGAEVISDSLISKGLSTAAETVFNATKKVLDKAW
                     SEVSPK"
     gene            14847..15728
                     /locus_tag="PC494_002214"
     CDS             14847..15728
                     /locus_tag="PC494_002214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDF3912713.1"
                     /translation="MNLYHLRYFVTLAHLEHYTKAAENLSITQPSLSHAISLLENELG
                     VALFEKEGRNIVLTKYGKIFLKDVEKSLEILDSSVKSLKITGTGEGQIDLAFLRTLGT
                     DFIPDIVHKFLKSNPAKSIDFKFHTGVTTDIIQGLKERKYDIAFCSKLEKEKGIEFIP
                     VAKQDLVLIVPYSHPLAAKDTIDLKETIPYPQIVFNQRSGLRYIIDDMFKKINQQPNI
                     VYEVEEDQVIAGLVAKNFGIAVVPNMNMLSFTKVKVIQIIHPSWERNFYLAFIKDRYL
                     PPAIKNFKNFVIKNAQL"
     gene            complement(15936..16799)
                     /locus_tag="PC494_002215"
     CDS             complement(15936..16799)
                     /locus_tag="PC494_002215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004455022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3800 domain-containing protein"
                     /protein_id="HDF3912714.1"
                     /translation="MLSSYVKRVSKIIKKKYIMFIDESGRADINHEDPFTLTGVIFEY
                     KYAVSQGDYVCSLRKEMDAFKEYCFGTSNIGIHLTDISRKSRAFEKFDDSQIKLFYDE
                     LPLFLSRLECTIISVTVDKARLKKYYAPSKEPYVVAFIHVLQNFYSFVNNETVESARI
                     VIESRDDVSNLKVQKAFFDVFNNGTIYLDIDEELRDKVKGFIIAKKEDADYREGLEIA
                     DILCNPLSRARRGLIEANPKCMQYGEKNKIFKSVRNKIYTPTSVNDIRNWGFKEVPIV
                     EPVGPWLEKMR"
     gene            complement(16954..18888)
                     /locus_tag="PC494_002216"
     CDS             complement(16954..18888)
                     /locus_tag="PC494_002216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp22"
                     /protein_id="HDF3912715.1"
                     /translation="MKKSLKKYLVLALTLVLVFACGVPESSAASKHVIIVNSRKNTLG
                     YFVNNKLVKEFRVATGKKGSETPTGKTKVVNKIKNRPYYKGNIPGGSPRNPLGDRWMG
                     LALKGTYGDTYGIHGNNNESSIGKHISGGCIRMHNKDVRWLFDQVPVGSDVIIDYSND
                     SYVKIAAKYKINLNQTGWKTENGKKYYVKSDGTYQKNSWLKVNGKMYYFDASGVMQTG
                     WKTINNKKYYLGTDGARVSGWKVIDGKTYYFNSDGVMQTGWQEKNGKKYYLGSDGLAV
                     TGWQEIDGNKYYFDKTGIMQTGWQQIDGKSYYLDKDGKMLTGSQKIDGKDYTFNEDGT
                     INPTWDTIIGANRFDTAKKISSVGNWNADSSDTVILVNGNAIADGITATPLASSYDST
                     ILLTNTANLPTETVEEMKLLAPKTVILIGGENAISSKLEQEIKTTFNTETKRIAGQDR
                     YQTATRIAEELGNREEIKTAYMVSGNGEADALSVASKAGEEKQPIILVNKDGITEESY
                     KWLTERKLENAYFIGGPSAINDSVIAKMNDITTEDISGNRIYGDSRVDTNAKVIEKFY
                     GDTDLQAVLVSKSDALVDALSAGPLAVKLHSPIVLMDNSGLSSEQQRVFANKKVETPY
                     QIGGGVSYIVMDKLMDILAK"
     gene            complement(19000..20013)
                     /gene="galE"
                     /locus_tag="PC494_002217"
     CDS             complement(19000..20013)
                     /gene="galE"
                     /locus_tag="PC494_002217"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HDF3912716.1"
                     /translation="MAVLVAGGAGYIGSHTAIELLESGYEVVIVDNLSNSNSIVVDRI
                     KELSKKPVKFYNIDIRNKDEMHVVFKENNIESIIHFAALKAVGESVEKPIEYYSNNLI
                     STLNLFELMREYGVKKFVFSSSATVYGDPHTCPILEDFPLSVTNPYGRTKLMIEQMLV
                     DISKADKSLDIALLRYFNPVGAHKSGRIGEEPNGVPSNLMPYITKIAVGKLKELSVYG
                     NDYPTHDGTGVRDYIHVLDLAAGHVKALQKLEENPGLVVYNLGTGKGYSVLDLVKAFS
                     KASGKEIPYKIVGRRAGDVAMCYADSSKAEKELGWKAKYELEEMCEDSWRWQSMNPNG
                     YEE"
     gene            complement(20037..20906)
                     /gene="galU"
                     /locus_tag="PC494_002218"
     CDS             complement(20037..20906)
                     /gene="galU"
                     /locus_tag="PC494_002218"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HDF3912717.1"
                     /translation="MTVKKAIIPAAGLGTRFLPATKSQPKEMLPIVDKPTLQYIIEEA
                     IESGIEEILIITGRNKKSIEDHFDKSVELELELEQKGKTEMLEMVRDISNMVNIHYIR
                     QKEPKGLGHAIYCAKSFIGDEPFAVLLGDDIVDSDVPCLKQLIDTYNEYKTTVLGVQK
                     IAKEDTNKYGILDVKHIEDRVYKVKDMVEKPAIEEAPSDIAILGRYIITPAIFSILEK
                     QTPGKGGEIQLTDALQTLGKQEAIYAYNFEGRRYDVGDKIGFLEATIDFALKRENLKD
                     DLMDYMRKKVSEK"
     gene            complement(21104..21424)
                     /locus_tag="PC494_002219"
     CDS             complement(21104..21424)
                     /locus_tag="PC494_002219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3912718.1"
                     /translation="MSSKYNVWTFNYEFLGLDSGDEKNNEVYYEIDLDEILNENYIDE
                     DIDSGLDSDGNSILGELISEMDIDEDVSVDMTYQELEVDLEDLDSYLDEDIDSDIKGI
                     LDEI"
     gene            complement(21414..23405)
                     /locus_tag="PC494_002220"
     CDS             complement(21414..23405)
                     /locus_tag="PC494_002220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3912719.1"
                     /translation="MLKLGEKIIYELSDGFELSGISRYSKEYKKLHITNLGNIIISKS
                     DEVNKDTGVKYIYSFSDNKEKLEAVLEDSQIIIYGNNLPFYIKSENSSKNVTANLTMK
                     ITLDEYDLICKSQREFIFYLKDNMTILSLDDNKFYMGGINKDNEKFIFISGKNRFEIN
                     FDDIERYILEDKRVSLKGYFHMEREGIIVRSVSIFNNNIDSVVPSDLNERVKDNQKIG
                     NLPKDCEIVFCKISGNIDGFDYKNTNMLLVKYQDQLIFINKKSKKTIVKSAKDNCSKL
                     NLGEDIILYDNKNVFNLHINDKNREIMQIDDLKDIENEIVGYTLKHAPFFIQEDFDSL
                     TILKSFQKEIISIKNSDIKDIVINKELENENSNFVETEIKFNNQKVLLNLSKSMVQKL
                     MQDVFIYAKQPLLKENSIEVIYKNWSKAMNDMIIFNFFGNIYYMKSEFDKILEKELND
                     EIRIEVINSLYKQIQEQRNNLDLLSAYMPRILENQEIDLFEKYNTKLDVQVFKQIKNL
                     LSDLSYNISSYLNEVEKSLDNIIFVISGEDKKKYNYRMLKESESASLDVFLKQAISRL
                     NHLVENMYPYYVDETSREMFKLFELLWKNYRNIDDDSIKEILFERITNTYVFKQLTLN
                     NSTKERRKDIIEKIYNSVDYGTNKLDENMFFTGGIKYVK"
     gene            complement(23528..26071)
                     /locus_tag="PC494_002221"
     CDS             complement(23528..26071)
                     /locus_tag="PC494_002221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPOR domain-containing protein"
                     /protein_id="HDF3912720.1"
                     /translation="MKVLSENNIIRNTVLNVTASFLKQESKINEKLDGVLEKKFEKVE
                     FNEAKYAELLKFNILFYKTLARNTEPLIGKWIVDKYIPEIDELEKDLELTTAKCRKYV
                     NKAMKEGLDSLKANDLNSFLAYDKMELSERRRRLEKDYKVLNLYKDLLNISLRKISLE
                     KKECGDLFLKNQADAKRELKREIIFCVNKILASNKDVVPNNVEENNEQDKVEIKATEI
                     EDLQLGKDNSENDMLLNEIKNSKVKHESKSNDIESKFIDKLNSLNNESVSQTIHNEYK
                     KLCGLEELHSVEGYGFGKEIIKDFACATVVLEFLKRRNRDLIEGAMRLTIIGEFGPEN
                     FKEFVDYVIKNKTEISEDTWNKAQNLIKDNYSELENHEIASKRTRRNKDIDIEEYIYM
                     IKNADKDICFRSSISIEDDAEEGVKEEIDSNNQDIGDVVEDKDTTDKEYDSNKEDIIE
                     PENKKSKKKAKLFGFIKKDNEEVEQEEENLNDISPDIILDKPVENHQVKSEEIEQNEL
                     KEIKQEEPSQHIEEERNVKIEKPINNNLDEKVSSNNESKLEKESKNLEDKKAKEIKEE
                     KLENEKSVVIPIKKKENSNKKSKNSSKDKYRENKKEMKNYVSDKEDSLDDEEVVSKKS
                     RLKETIIAVVIVVIVGVGYFITVGNNKKNDKENIPKSSTQQQANNKLTEEEKKAQAEK
                     EKKEAEEKAKAEKEAQEKAQAEKKAKEMEAYKDGKGVYYTVYAGSLKVEKTAKETAKE
                     YEAKGISSTIIQENGYYKIKIGDYSQYGEAQEKCNELAKKSIDTYIAMYDKYYDYKLE
                     ELKESAPSLSAEELKQKYEDLRSELKNKSGYREYVKHLDKLYEEIVEGA"
     gene            complement(26349..26683)
                     /gene="rnpB"
                     /locus_tag="PC494_002222"
     ncRNA           complement(26349..26683)
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="PC494_002222"
                     /product="RNase P RNA component class A"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00010"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00010"
     gene            26815..27492
                     /gene="srtB"
                     /locus_tag="PC494_002223"
     CDS             26815..27492
                     /gene="srtB"
                     /locus_tag="PC494_002223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sortase SrtB"
                     /protein_id="HDF3912721.1"
                     /translation="MKKLYRIVINIILVLVILYSGFNIYSKLTKYNHDTKISSELQKK
                     EYKKEDLSNINSDFKFWLSVENTNINYPVVQSKDNSYYLDKDFYKKDSISGTLFMDYR
                     NKSIDDKNIIIYGHNMKNKTMFNNLNKFKDADFFKKNNKIKITLNGKEFLYDVFSAYI
                     VESDYDYLKTNFNNESDYQNYINDITSKSLYKSPIKVNSNDKIVTLSTCTYEFDDARM
                     VIHGRLI"
     gene            complement(27652..27726)
                     /locus_tag="PC494_002224"
     tRNA            complement(27652..27726)
                     /locus_tag="PC494_002224"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(27692..27694),aa:Thr,seq:tgt)
BASE COUNT         8973 a         4836 c         3110 g        10889 t
ORIGIN      
        1 agcttctttt taattgttaa aaagataaaa atatatttga tttaatagaa aaagagtgcc
       61 tcataaacta aaaagttcat tttgagacac ttccttaata ttaataaatt aattggctta
      121 aaattactga ttgataatta taaagtacct ctgttaaagg agtaaattct gaaccgattc
      181 caaatcttaa ttctgtaaac gcctctaaat aatctgggtc acatacatct tcttgtgtta
      241 aatcttgttt caccatttca gtagcaagat aaattgctac tgatggtaga aaagcatcca
      301 ttggcatagg atatccacca agtctatttg acatgccaaa agccttagcc ttttcactta
      361 tcatgtcgtt tattttatca taattttgag catctttttc agatattttt agacccataa
      421 cactaggata tgtttgtatt ggtgatggat tgctttgctc tgcaactata tactttaatt
      481 ctaaagcctt agtcaatata acttcatcca tatactcatt tacaccaaat acatttatat
      541 cttttccata ttttttaact tgtttttcaa tatcttcatt taaaaactgc ttaactttgt
      601 ttttgtcttc ttcagtattt atatttggag tattaacttg tacaaatggc aatcctatat
      661 ttttgcaagt ctctttaatc atttctaatc ttttggctat attaacatct ttcaaatcat
      721 ctgtagaggc ataatgaata aaagcttttg ctcccatttc ttttgaacgt tcagctaata
      781 cttttcctct ttcctctgca ctaaccccta gattcacatc aacaaattgg cttaattggt
      841 ttttatcatc tcccataggg gcagaaatag ttattatttc tggacgcttt tcctttacct
      901 tttgtaaagc aggtaaaagc cctgcttggt cagttgaaac tacaatagcc tgaacttctt
      961 tatcgtcagc caactttact atcttattaa tagcactgtc tatattagaa gtaaaattct
     1021 ctggcaatac aacatgcttt atagtttgtt taactttagt ttgaccatct ttgtctttat
     1081 caattttatt ctcttcctca tattcttttg ccatctcttc caccatattg tattgtactt
     1141 tattttcaga taatggttga gttaccactg caactttaaa atcatctata attttctctt
     1201 tatctttctt gcctacaagt aaactacaac ctgtaagtcc aataattaaa catatggata
     1261 gcataaatgc tgttattttt ctaagcatta attaaaacct cctaaatttg tacattctta
     1321 tcactattac taattttatc atacttcaaa gaaaaattat attataaaaa attatataca
     1381 tgctattata atccaatcta aaaagtacta tgggtagatt aggtttagat taaacctacc
     1441 catagtacta aaaattaata tattataaaa ttaaattaat tacaaattat tatgctactt
     1501 gtttgttgct ttttataaag ttaccaacta ttccacccaa tatagctggt attacccagt
     1561 taaagcccaa acctgcaagt ggcaagcttt gtataaatgg aacagctcct gtcattccat
     1621 ttatagctga taataaacta atcactaatg taacatatgc tgcaccttta aaagcattat
     1681 cattctttat atgtttacca gccaactcca taacaactat tgctaataaa acaggatata
     1741 tagtttgtag gattggaact gatatggcta ttatagaatc aacacctaaa tttgatataa
     1801 gcatactagc tacacatata cctataacca gttgtttata actcgcctta cttattcctt
     1861 caaaataagt tgatattgat gctgttaaac ctgtagaagt agtcagacag gcaagtgcca
     1921 caattacacc taaaattacc tttcctactt gaccatataa caatatacta gttatttcaa
     1981 ctaataaaga tgcttgaggt atactagtat catataaagt tgaaactgtt gcacctaaat
     2041 aagtaagacc accatatact actgctagaa atacacaggc tacaaaacca gctttaatag
     2101 tcattcctat ttggtcttta tctgatgtat atcctttagc tattatagac atcaacatta
     2161 tagttgccat agatgctgca cctagagcgt ccattgtttg ataaccttgt gatatacctt
     2221 caccaaatag atttttatct atcatatgct caggactcat aggtcctgct ggagaaatta
     2281 taccctttac tattaaaaca aataatacta ataataacgc tggagttaaa tacttaccta
     2341 ttatgtctat aaccttagaa gacctaatag taaatgctaa agttagccca aagaagatta
     2401 ttgaaaatac agctttagct actggaccat ggtctccaaa tataggcata atacccattt
     2461 catatgttgt tgcgcaagtt cttggtatta caagaagtgc taaacatgct agagcagcta
     2521 cactcattac tcttgctaac cctttaccag ctctcctaag tacatcatcc atgcttccct
     2581 tacatcttgc tgttgctata ataacaagca ttgctatacc agcatctgca acaacaaatc
     2641 caataagagg aattaaccag tctttgccgg attccatccc taaaaatgga ggaaacataa
     2701 gatttcctgc accaaagaac atagaaaata aagcaaaacc aactataaaa atatctctca
     2761 tctgcttact cacactaaat tacccccttt gaaaatattt tgaatattaa gataatctta
     2821 ctttattttc agaaaaatgt caatctggta aaaattcaca cattgttaac gttttcccaa
     2881 tttattttat gaatattttt ttcattttat gataattccc atcaatttcg ttaaatcaat
     2941 tgcttgtgac acatcaaaaa ttgctcctct aatatcatct ataccaatct caattccctc
     3001 aatattatta gtagtaaaat ctatgccaga aagtttagtt ccattaaagt ttgctttttt
     3061 taaatttgta tactcaaata ctagattgtc accttttact tcttgaaata cagaattttc
     3121 aaaatttgaa tctaagatag aaactatctt aaatttagag aatgaaaagt tagaatactt
     3181 acctaaaaca tccttgaaca aaacgttttt aagtatacaa tcatcaaatc taactcctat
     3241 caatttacta tttttaaatt caactctgta tatacttcct ccatcaaaaa atgtatttga
     3301 taaattgcag ttttcaaata ccacatcaag taaatcaatc ttttttaaat tacaattttc
     3361 aaaagacaca tttctaaata tacaagattc aaagctaact cttacagaat ctaaatcact
     3421 tataacttca ttttctataa ttttattaaa tattttttca tcattaaata tatcttcaag
     3481 tatatcttca agattttcaa taatttctaa ttctcctgta aatttaggtt tttgcacttt
     3541 aataatttta gtcattttcc cctccactat aaattatatt atttttgata ttattttttt
     3601 taatatatta acttaatata catatttgat atattaaaaa gtttttacga aatatccatg
     3661 tattcagtac ttttataatt atatcacaaa ctcatttata ataaacttcc attaatagta
     3721 taaaacaagt tagaataatt gacattatat tcatacatat tcaattattg gaaaaagtaa
     3781 tttttttcaa taaataacct taatttttta taaaatcgac aaaaaaacga ataattttat
     3841 tatatttatt gtaaataata caatattacg atataataca acagaaaaac aaatagaaaa
     3901 tgttcatata atattagtaa tacggtctaa tagtttctac aaactcacct taaatgggtt
     3961 ttctatgaat agaatgtcaa ctctgaatat atgttctatt ctatctatat gaatatatat
     4021 ttttttgttt atatcttaaa gttttttgga ggtaaaaatg gtaccaaaca ctaacaatgt
     4081 acaaccaggt ggaaataatt catcattaag ctttttagac aaaatgttta aatttagcga
     4141 acgtggctct agccttaaaa cagaggtaat aggtggagtt actacatttt taacaatggc
     4201 atacatagtt ttcgtaaatc cagcaatatt atctgaagct ggaatggata aagccgccct
     4261 tataacagtt accatactag ctacagccat tggtacactt atatttgcga ttttaggaaa
     4321 tgcaccattt gctctagctc ctggtatggg attaaatgca ttcttcacat actctttggt
     4381 tataggtgca ggaatcccat ggcaaacagg tcttggggta gtttttctat ctggatgtgt
     4441 cttctttaca ctcgcagtaa caggtcttcg aaagacaatt gcagacgcaa ttcctagaga
     4501 attggcagta gcatcttcag caggtatagg tcttttcctt gcttttgttg gtttaaaaaa
     4561 tatgggtgtt ataatagcta atccagatac tatagtttca cttgcagatt ttacaccaac
     4621 agttttaata gctctttttg ctcttatctt aatggcaata ctagaatata aaaaagttaa
     4681 aggtggaata ttgataagta tagtagttgc aacaataata tctgttatat ttggatttgt
     4741 ggagttgcca acagcaataa tctcgacacc tcctagtata gcaccagttg cttttaaatt
     4801 agatattgta ggtgcattga aattctcatt aattggacct atattctctt tcatgtttat
     4861 agacatgttt gattcattag catttcttat tacttgttgt aaacaaatgg gtcttgaaga
     4921 tgagaatggt gaaataaaag atttaggaag aatgttatat gcagatgttt cttctacttt
     4981 aataggctca ttcttaggaa ctagtactgt tacaacattt ggagaatctg cttctggtat
     5041 tgcagcaggt gcaagaacag gacttgcttc aatagtaaca gcagcattat tcttagctac
     5101 acttatattt acaccattac ttggtatagt tcctacttac gctgcagctc ctgcacttgt
     5161 aatggttggt gtattcatgt ttgaaagcat aaaacagatt gattttgctg atagcaaaat
     5221 agctgtacct gcttttgtta cagttttatt gatgccttta acttatagta taagtattgg
     5281 tttatgcttt ggatttattt catatataat aatgcatgta gtagctaaag aaactgataa
     5341 aatcagtatt acactttgga ttataggttt acttgcagtt gtaaacttag ttctaagtta
     5401 atatttttaa atagttctag gtcaatattt taaattatat agaataaaat cttatttatt
     5461 ttaaatttat aaatagcaaa atcactttat atgtaaattg attttgctat taactttgta
     5521 tagaaaattt attatcataa tatatagata taaaaatata tagaaaagga gtggtgttta
     5581 tgtcacaatt acttataaaa aatgcatatc taattactat gaatgcagat agagaggtat
     5641 atgaaaatgg aagcatactt attgaaaata atattataaa agaggttggt aagtttgata
     5701 ttaatattgt agataaagat gcagagatat atgatgctaa aggaaaaata ctaatgccag
     5761 ggctagtcaa tactcatgtt cacttatctc aacaattagg acgtggtctt gcagatgatg
     5821 ttgtactttt aacttggctt agagaaagaa tttggccata cgaaagtagc ttcaattatg
     5881 aagattcctt gatttcatct actgcatgtt gtgttgaatt gataaaatct ggtgtcacta
     5941 catttttaga atctggtggt caatatgtag atgctatggt tgaagctgtt gataaaactg
     6001 gacttagagc ctgtttagct aaatcagtta tggatacagg agatggtctt cctgaggcat
     6061 ggcaaaaaac tactgatgag gaaatcaaca ctcaattaga cttattccat aagtttaata
     6121 atacatctaa tgagagaatt aaaatatggt ttgcattaag aactattttt aatacaactg
     6181 aagaattact tgttagaact aaagaactag ctgataaata caatacaggt atacatatgc
     6241 atattgctga aatagctgat gaaatttcat ttgtaaagca aaacaatgga gttggaacag
     6301 ttgaatacct tgataaacta ggtgtattag gaccaaatct tttagctgct catacagttt
     6361 ggcttactca taaggaaatt gatttattta gattacatga tgtaaaagtt tctcatgacc
     6421 caggttcagc tatgaaagtg gttctagggt ttgcatcaat tcctgaaatg ttagaaaaag
     6481 gaatacctgt ttcaattggt actgatggag ctccttcaaa taatagaatg gaccttatga
     6541 gggacatgta tcttacatca ctaatacata aaggaagaac tttaaaccca actgtcgtac
     6601 cagctgaaga agtcttagaa atggctacta taaatggagc aaaatgtgct ttactagaaa
     6661 aagaaattgg tagtcttgaa gtaggaaaaa aagctgatat gattattcta aatccagata
     6721 caattcattg tttaccaatg cataatccaa ttggaaatat agtttattct atgactagtg
     6781 aaaatgtaga ctctactatt tgtgatggta aatggttgat gaaggaaaga aaagtattag
     6841 ttgtagatga atctgaatta ttaaataaag ttaaaaaaca agcttctaaa ataaaagata
     6901 aagcagaagt taaaattcca tctaaattta aaattataaa ataacataaa tttcaattgt
     6961 tttgtaaata tgaatatata aatatattta tatacatcat atatacaaaa caattgtttt
     7021 tttattttat attcattagc attgctcata aaatacacca taattccaga aaaaataacc
     7081 aatcagttag gattacatca tctaagcaat atataaacgt cttagtttat aagttttatt
     7141 ctactcttat ctaaaaccat ctttaaagag ttttcaactg tttcaattac atctttataa
     7201 ctcaagtaca catttgcgta gatacaatct tcatataaat tatattcagt tactctacaa
     7261 tacagcagtt ttcctccatc taataaattg ctcaaaatat agttttcttt tcttgggaca
     7321 tagcctatca catatccagt ttcaccaact attttaatag ctttttcatc atatagatta
     7381 tctttctctc tagttaaata gtatatctta cttttctcca attctttttc aagatattct
     7441 ctatttctaa accttgaacc agcaacagct attgaagtca aatagatatc cttaccatgt
     7501 tcatctactt ttattttttc aatatttaca aattcttttt ttaaattatt actttcatat
     7561 aatactcttc ttaattcatc cttcaatata acattttttt ctttttcata cgcttcttta
     7621 acaattttta attcttcaag agatagtttc tctctgtatc tttttaagat atttatggat
     7681 tcttttctta cttcatttat atttccaaat attcctttta aagatatatt ctttccttca
     7741 ggatatagtg atttacttcc tttaagcaca ataaaaaata acatatcatc ataatattct
     7801 tgagtcaatt tatctttttc tatatctttc atttttccaa ttaaatcatc tattttaaac
     7861 gtctcttcaa aaaaatttaa taattttaat ctagaacttg tcgttccctt tttagatata
     7921 tgccaatata cctcaaaatc tctaatatct ctatttagat atggcaacaa gtcatcaaaa
     7981 gataagttta catcataaat ttctgacatt tttataatat cttctgtttt tccactagca
     8041 tctcttaatg cttcaaaata tatatttttc catttttcac tgagcaagat accatttatt
     8101 tctttttcaa attcaatctt attgcactct atattttcat cttttaagac gtttatagct
     8161 attaggaaaa ttgaatataa actttcaaag ttagtcccat aatttactac agtaggtaaa
     8221 aatcgattca ctaattctaa tttattacct atatatttaa attctacact tagcaagtaa
     8281 ttgcatataa gacgtgctaa attatttatc ttttctttat ctaaatctcg tttttcaaga
     8341 tattcattca aatctacaat tgaaataata tagttcatca ataatcgttc gtactttgta
     8401 tccttataac catcttcaat tagataggaa tttattttag aatctaaatt ttccatatta
     8461 acaatagcaa atacttttat tgaacctgta gcctttttag ataaattaaa taaatatgta
     8521 ttgtaaaatt caagtttttt aatagtatta ctcagataaa atacgtattc tccagattta
     8581 gaaaatgtat ctacaacttc tcttaagttt tctacattta gatatttctc acttaaaact
     8641 aaccctagtt ttacatactc aactttttta ctcttatata ttaattcttt agttaattta
     8701 tataaccatt tctcatcaat aatcatttct tttaccaaag tatttatctt tttcataaaa
     8761 atttcgaaat aacaaattaa agacttagaa ttactaccct ccaataaata aatttcatta
     8821 gattcacttt tatacatatt taaaatttca tctactagat tatttgcaag ctctacttgt
     8881 tctcttaacg gtatactttc atatatacat aggtaattca tttcaaatga ttctttgtat
     8941 ccatcataac cattaaattc ctgcaatcgc ttaaaaacat tctccaccaa attatcctcc
     9001 tttacatgat gtaatttata ttgattatac tacttatttc atcaagttta catttatacg
     9061 caaaaaaata ttactagaaa ttgaaattct agtaatatcc ttattattaa ttatgtaaat
     9121 accctatctt ataactgtaa ataatatcct tattaatttt aattactttt aataaaaatc
     9181 tatcctagat ttagacttct ctatgcatat attatactaa tattagacat cataatcata
     9241 cactttttct ttttcatatc tcatgtttac aaacaatgca agtaaaattc caacaaatgt
     9301 tattgccaca ttaaacaata caacatattt tggtccatta actccccctg attttgtaat
     9361 aatacctgct atatttaaaa taacatagtt tgctatacta gatgcaatca taactataga
     9421 tgttattttt cctttattag ttggaaacat ttcatttgca gttgacgttg ttaactgaag
     9481 aacacctcct gctgctgaat aacctattac aaatccccct aacatacaaa tagttggagt
     9541 ttgaacaaaa tatacaacta atagcataag taaagctatt ataggatata taactaatat
     9601 tcttattggt ttaatatatt ttttaataag taaagaagtt attaatactg cacatattac
     9661 tcccattgag taaaaggatt gaatttttgt agggtcagcc atcccataca atttacccaa
     9721 ttcctgatta caatttaacc ataatacaaa tgtagatgta catgtaaatc caatacaaac
     9781 aagagctata cttgttggtg taaatttcat cttctctgat ttaactgttt tgcctttgtt
     9841 atcaataaca ttattagctg gtggaaatgg taacacagct atcaaaaagg catctactac
     9901 aataagaatc gctgttacta taaaaataac tttaaatgat attgaatttg ctgcaacaaa
     9961 tccaattata aaaggaagca aaaattgtgc taaagctatt gtaaatttag taaacatatt
    10021 tgctattgtt cctaaactag caaatatctc catacaagaa ggagttacac aggtatctaa
    10081 gaatgaattt gctgcccctc caattattgc aaatacatat gctatataaa aatttggtga
    10141 aaatacaatt ccaacaaaga aaattgcatg tagaaagttt cctataagac cacttacttt
    10201 tcttccatac ttatctgaaa taggtcctgc aaatggataa gatataagtc tccctaatcc
    10261 tagtgcagca ataacagcta aaacaatact tacatccaat gttccatctg ataatgtttt
    10321 agccccccac attgatgaaa attctggttt gtattgtcct aaaattgaaa ttccaatacc
    10381 aagtaaaaaa tatgaaaaat acaacgctat ggcagtagga taatattttt tattgttcat
    10441 aatttttctc ccattcttgt taatttatta acatttttgt gtacaataaa ctcatcccca
    10501 taatggattt aaagtatagt cagttaaaac ttcaaattta actggactat gaggcaaaac
    10561 ccactatgac aatttgtaat ttattattaa aaatattgaa atacgtatgt tttttcattg
    10621 tttaagatat tactcttatc tatttaaagc ataattcatt aacttcttct acaggcattt
    10681 ctaatccagt atatagatta aaagcttctg ctccttggta taataacatt cctaatccac
    10741 caatagcctt acatccatta gcttcagcat cttcaatcat ttttgttttc ttaggattat
    10801 aaacgacatc tgttactact aaatcttttc ttaaaacact agtatctttt atatttgttt
    10861 cattgtcata aggcttcata ccaataagag ttgcatttgt caatatatca cttgattgta
    10921 tctcctcata aagtttgttt gtatcttcta aatcatatag attaacaaca cattctggta
    10981 catctttttt tatattctca actgtttgct ctgctctttt ataaaaatca tccttaggat
    11041 taaagataga tatttctctt gctccatcta aagcacattg tacttgtata gcagttgctg
    11101 caccaccagc acccataatt gtaatctttt tacctttaac ttctacccca ttttctttta
    11161 aattacgaac atagcctact ccatctgtta tatgaccaac taactttcca ttgtcattta
    11221 caattgtatt acatgctcca attatacgag ctgctggaga aagttcatcc atatattctg
    11281 taacagcaga tttacatggc atagtaacat tggctccttt tatattaaaa gtttttattg
    11341 ctaaaagtgc ctcttttacc ttatctactg tgatatcaaa ggctaaatat ctataatcta
    11401 aatctaattt cttaaaacta taattataca tcactggtga tttagagtga ccaaccggtg
    11461 tacctattaa tgcaaataat cctgttctac ctgaaatttc cataactata atctcctctc
    11521 aatattatca ttttctttgc aaataaccta ttcagttatt tacaaagaaa aatttattta
    11581 ttatttatat atttaatgct acttcaaaag cttcttttgt tgcatctaat gccctacgag
    11641 cttttactgc atcaccaaca atataagttt cttttacaac ttcttttata acttcactta
    11701 atgggtcgta attacgagaa cccatagcaa gtactactga atcaaaacct tttaaatcat
    11761 gctctgtgcc atctgtaagt aaatagtcga caccatcatc ataaaattta gaaacttttg
    11821 caccagtaat ggtatgtata ttataatttt caaaatcatt cataaggaat ttacggtgtt
    11881 ctgaaattac atctgcacca acttcttctc taagctcaat aacagtaacc tcatgttctt
    11941 gttctccaag gaaggctgcc acttcacatc caaccattcc acctccaaca acaagtactt
    12001 ttttcccaca agatttttta ccatcaagaa ggtctacagc atgaattaat cctgaatcat
    12061 tgattcctgg tataggaagt acaagtggag ttgctccagt agctataata actacatcag
    12121 gtgatttctc ctttataagt tctactgtag cttctgtatt agtacatatt tttacaccat
    12181 attgattaca ttttgaaata taacttctaa ctaagttagt aatatctcct ttccctggag
    12241 gatatgcagc taaacgcatt tgcccaccaa gaacttcaga tttttcaact aaagttacat
    12301 tatgtcctct tttagcacat acccatgctg caagcatacc tccaacacct ccaccaacaa
    12361 caagaacttc tttgctaatt tcagctggct taagctctgc ttcatgtcct aatataggat
    12421 ttgcaagaca ggctataggt ttgccttgga acatatttgg tacacatcct tgtaagcatg
    12481 caatacatgg tatcatttcg tctagttttc catttttagc tttattaggc atttctgggt
    12541 cagccaagct ttgtctaccg aatgctacta aatcacatct tccttgtctg accattaact
    12601 cagcaaactg tggctctgta taacgtccaa ctgttattac tggtatacta acagcttttt
    12661 ttatttcagt aactaattct gcactgaatc cagcatgtaa agtcgtagga gcccacatat
    12721 attcatcatg tatatgtata ctacgtgaaa catgaagtcc atctattcca caatcttcta
    12781 gatatgctgc tattactgaa ctatcgtgta catcaattcc tcctggaaca tcatcagtgc
    12841 tgtttatacg acataatatt gctagagaat ttcctacttt tttacgtata ttttcaatga
    12901 taagacgagg taatctcatt ctattttcaa aacatccacc aaactcatct acacgcttat
    12961 ttgttctttg tgatataaaa ctactaacca gatatccatg agcgcagtga acttcaacag
    13021 catctgcacc agctttttgt gcacgtaatg cagcatctcc ataagattct ataagttcat
    13081 atatttcttc tgttgttatt gctagtggtg tattacgacc atttgatgca ggtattgcag
    13141 aagcagcttt taatggatgt cctgctactt tttcatttcc ttcagaacca gcatgttgta
    13201 attgtataga taccttcgaa cctgcatcat gacaagcatc tattacattt ttaaaactat
    13261 ctattgtgct atcatcatat aaacaaggct tacgaggacc tccttttgct tttttgtcta
    13321 caacactaga ttctatagtt attaatccaa aaccacctaa agcacgctca agataataag
    13381 ccttagaagt ttcacttaaa gtaccatctg tgtttgcaaa attgtttccc ataggaggaa
    13441 ctacaaaacg atttggaact gtcattgaac caattcttat aggtgtaaac atagaactaa
    13501 tcttcataag gttttccttc ctttcaagtt ttatatttaa aagttttata ttataatact
    13561 ctgtatattt ttatattata taagtttatt ttggagatac ttcagaccat gctttatcca
    13621 aaactttttt agttgcatta aatacagttt cagcagcagt ggataaccct ttagatatta
    13681 gagaatcaga tattacttct gcccctatga ctcttggtga tatattgtgt tcttttatta
    13741 ttttcacaaa ttcctctgtg tttccatatc cttcacctgg agccaaacgg tcatgtagtg
    13801 attcatccct aagtttttca taaggagttt ctaaaacatc acacacttga attgatacta
    13861 tcttatctgc tggaacaggt gcaaggtcct ctgctgtctg ctttgctcta gcccagtgcc
    13921 aagtatctaa tataagcatt gcattttcac gattacatcc tttcacaaca cgccatgcag
    13981 tagccaaatc tggtacacca ctatatggca taaactcaag acctataata agttcacctg
    14041 ctctgtcaca taattctccc aatgcagtta taatttgttc ttctggtatc atctctaata
    14101 atccacaatt tatatgttta acattaaata agtgagccat atgataaaca ttttgctctt
    14161 tttctctttg agcttccgtt ctatcttctt ctcttcccca ttgagttata tattctactt
    14221 ctgtaacttt catatcatat tcattaagaa ttgcaatcat ttcttcatct gtaacacctg
    14281 cattttttgc atcaatataa ttttcagcac gcaatccaat accatcaaac ccagcttctt
    14341 ttgcaatacg aactctatca cggaatgaaa cttctgttcc caatgtataa gaactaattg
    14401 taattggaat attaagattt ttttgattat tcatagctta aatttgcccc ctttattttc
    14461 tttataatta atagtatttt tgattttata tttttattta tcctactagt agtattattt
    14521 taccttaaaa ataaaagtat tttttgattt ctatttatct agattttata aatttattgt
    14581 atcacgagac tttactaata acaaattgat aatttcctat taattcatag attttgttta
    14641 tagattttat ttataagata attcttgtat ttttctatta ggtcgtataa atatatttat
    14701 cttataattc agacaaaaaa cgataaattt ttttaaaagc ttttattctt actctataat
    14761 catatataat aaaaatgtaa aaatatctta aaggttaact tctacaaata tataaataaa
    14821 aatacctatg aaaggatgaa caaaaattga atttatatca cttacgctat tttgttacat
    14881 tggcacattt agaacactat acaaaagcgg cagaaaattt atctataaca caaccaagct
    14941 taagtcatgc tatttcttta ctagaaaatg aacttggggt ggctctattt gaaaaagaag
    15001 gtagaaatat agtccttact aagtatggaa aaatattttt aaaagatgtg gaaaaatcat
    15061 tagaaatttt agattcaagt gtaaaatcat taaaaataac tggtactggt gaaggacaaa
    15121 tagacttagc ttttcttaga acacttggta ctgattttat cccagacata gtgcacaaat
    15181 ttttaaaatc taatcctgct aaatcaatag attttaaatt tcatactggt gtaactactg
    15241 acattattca aggtcttaaa gaaagaaaat atgatattgc attttgttcg aaacttgaaa
    15301 aagaaaaggg aattgaattt atacctgttg ccaaacaaga tttagtacta attgtaccat
    15361 atagtcatcc actagctgca aaggatacta tagatttaaa agaaaccata ccttatcctc
    15421 aaatagtatt taatcagaga agcggtctta gatatataat tgatgatatg tttaaaaaaa
    15481 taaatcaaca gcctaatata gtctatgaag tagaggaaga ccaagtaatt gctggattag
    15541 ttgcaaaaaa tttcggaatt gctgtagtcc caaatatgaa tatgcttagc tttacaaaag
    15601 taaaagtaat tcagattatt cacccaagtt gggaaagaaa cttttactta gcatttataa
    15661 aagatagata tttgcctcct gcaattaaaa actttaaaaa ctttgtcatt aaaaacgctc
    15721 aattataatt tattaataaa ggggttattt ttaaatatcc tcttttattc tttttataaa
    15781 ataaaaaaat ctatactttt aaaagtatag attcctaact gacagtcggc atccgagtct
    15841 cagtaattat cgttatacaa cagcaactgg attcagttcc tgaataacta ggttacttac
    15901 attatatcag attttttaaa atttgtcaat tgtatctaac gcattttttc aagccatggt
    15961 ccaacaggct ctacaatagg aacttcttta aatccccaat ttcttatatc attcacactc
    16021 gttggagtat atattttgtt tctgacagat ttgaatattt tgtttttttc tccatattgc
    16081 atacactttg gattagcttc tattaaccct cttcttgctc tgctaagagg attacataaa
    16141 atatctgcta tttctaaacc ttctctatag tcagcatctt cttttttggc aattataaaa
    16201 cccttaactt tatctcttaa ttcttcatct atatctaagt atattgttcc attattaaat
    16261 acatcaaaaa acgccttttg tacttttaag tttgagacat catcccttga ctctataact
    16321 attcgtgcag attctacagt ttcattattt acaaatgaat aaaaattctg aagaacatgt
    16381 ataaaagcca caacatacgg ttcctttgaa ggtgcataat atttctttaa tctagcttta
    16441 tctactgtta ctgatattat agtacactct agtctagata gaaataaagg caactcatca
    16501 tagaataact taatctgtga atcatcaaac ttctcaaatg ctcttgattt tcttgatata
    16561 tctgtcaaat gtattcctat gttactagtt ccaaaacaat actctttaaa tgcatccatt
    16621 tctttcctca aagaacatac ataatcgcct tgacttactg catatttata ttcaaaaatt
    16681 actcctgtca atgtaaatgg gtcttcatga tttatatcag ctcttccact ttcatcaata
    16741 aacattatat attttttctt tataatctta ctcaccctct taacatatga tgatagcatc
    16801 tatattcatt ttatatgagt tttaaaaata ttccaagatt tttatataac ttaaacttaa
    16861 ttttatacta aaaaattgag atgtaaaaca atcaagcttt tattgattga atttcacatc
    16921 tcaattataa ttatttttca atatatattt ttactatttt gcaagaatat ccattaattt
    16981 atccattact atataagata ctccgcctcc tatttgataa ggagtttcaa cttttttatt
    17041 tgcaaatact ctttgttgct ctgatgataa tcctgaatta tccattaaaa ctattggtga
    17101 atgtaatttt acagctagtg gtccagctga taaagcatct actaaagcat ctgatttact
    17161 aactaataca gcctgtaaat cagtatctcc atagaatttt tctattactt tggcattagt
    17221 atctactcta ctatctccat atattctatt tcctgaaata tcttcagtag ttatatcatt
    17281 catttttgct attactgaat cgttaattgc acttggtcca cctataaagt atgcattttc
    17341 taattttctt tctgttagcc atttataaga ttcttctgta attccatctt tattgactaa
    17401 tattataggt tgtttttctt ccccagcttt agaagctaca gataaagcat ctgcctcccc
    17461 atttccagaa accatatatg cagtttttat ttcttctcga tttccaagtt cttcagctat
    17521 tcttgtagca gtttgatatc tatcttgacc tgctattctc tttgtttctg tgttgaaagt
    17581 agtttttatt tcttgctcta atttagaact tattgcattt tctccaccta tcaagattac
    17641 tgttttaggt gctaataact tcatttcttc aacagtttca gttggtaaat tagctgtatt
    17701 agtaagtagt attgttgagt catagctact tgctaaagga gttgctgtta taccatcagc
    17761 tattgcatta ccatttacta atattacagt atctgagcta tcagcattcc agtttccaac
    17821 tgaacttatc tttttagctg tatcaaatct atttgcacct ataattgtat cccatgtagg
    17881 atttatagtt ccatcttcat taaaagtata atctttccca tctatttttt gagaaccagt
    17941 tagcatcttt ccatctttgt ctaaatagta agacttacca tctatttgtt gccatcctgt
    18001 ctgcattatt cctgttttgt caaagtaata cttattacca tctatttctt gccatcctgt
    18061 tactgctaaa ccatcagatc ctagatagta tttctttcca ttcttttctt gccatcctgt
    18121 ttgcattact ccatctgagt taaagtaata agtttttccg tctattactt tccatccaga
    18181 tactcttgct ccatcagttc ctaaataata ttttttgtta ttaattgttt tccatcctgt
    18241 ttgcattact cctgaagcat caaagtaata catttttcca tttactttta gccaactatt
    18301 cttttggtat gttccatcag attttacata atacttctta ccattttctg ttttccatcc
    18361 tgtttgattt agatttatct tatattttgc cgctatcttt acatagctgt cattactata
    18421 atctataatt acatctgaac ctacaggaac ttggtcaaat aaccatctaa catctttatt
    18481 gtgcattctt atacatccac cagaaatatg ctttcctata gaactctcat tattatttcc
    18541 atgtattcca tatgtatctc cataagttcc ttttaatgct aatcccatcc atctatctcc
    18601 taatggattt cttggacttc ctccaggtat attaccttta taatatggtc tattttttat
    18661 cttgttaact acttttgttt tccctgttgg tgtttctgac ccctttttac ctgttgcaac
    18721 tctaaattct tttacaagtt tattatttac aaaatatcct agagtatttt ttcttgaatt
    18781 tactataatc acatgtttac tggctgcgct tgattctggt acgccacatg caaatactaa
    18841 aactaaagtc agtgctagta ctaaatactt ttttagactt tttttcacta taacttcccc
    18901 ctcttttaga aacattacta catgtgtcta attataacat aaaattacca ataccttata
    18961 tttacaaatt tgttacattt atacatataa gtatatattc tattcttcat acccattagg
    19021 attcatactt tgccatctcc atgaatcttc acacatctct tcaagttcat acttagcttt
    19081 ccatccaagc tctttttctg cctttgaaga atctgcataa cacatggcta catctccagc
    19141 ccttcttcct acaatcttat atggtatttc ttttccactt gctttagaaa atgcttttac
    19201 taaatcaaga acactatacc cctttccagt tcctaaatta taaacaacaa gtcctggatt
    19261 ttcttctaat ttttgtaatg cttttacatg accagcagct aaatctaata catgtatata
    19321 gtctctaact ccagttccat catgtgttgg atagtcatta ccataaacac tcaattcctt
    19381 caatttacct actgctattt ttgttatata aggcattaga ttgctcggaa ctccatttgg
    19441 ttcttcacct attctaccac ttttatgagc accgactgga ttaaagtatc ttaaaagagc
    19501 tatatccaat gacttatctg cttttgatat atctactaac atctgctcta tcataagttt
    19561 agttcttcca tatggattgg ttacagaaag tggaaaatcc tctaatatag gacaagtatg
    19621 tgggtctcca tatacagtag ctgaagaact aaatacaaac tttttaacac catattctct
    19681 cattaattca aataaattta aggtacttat tagattattg ctgtaatatt caattggttt
    19741 ttctactgat tcaccaactg cttttaaagc tgcaaagtgt ataattgatt caatattatt
    19801 ttctttaaat acaacatgca tttcatcttt atttctgata tcaatattat aaaattttac
    19861 tggtttttta gataattcct tgattctatc aaccactatt gagttgctat tacttaagtt
    19921 atcaactata acaacttcat aacctgattc taaaagttct attgctgtat ggcttcctat
    19981 atatcctgct cctccagcta ctaaaactgc cattgtaatt acctcttttc taatatttat
    20041 ttttcactta ctttttttct catatagtcc attaaatcat cttttaaatt ttctctcttt
    20101 agagcaaagt ctattgttgc ctctaaaaaa ccaatcttat ctcccacatc atatcttcta
    20161 ccttcaaagt tataagcata aatagcctct tgttttccaa gagtttgaag tgcatctgtc
    20221 agttgtatct ctccaccttt accaggtgtc tgtttctcta atatgctaaa tattgcagga
    20281 gttattatat atcttccaag tatagctata tcagatggag cttcttcaat tgcaggtttt
    20341 tcaaccatat ctttaacttt atatactcta tcttcgatat gttttacatc caatatacca
    20401 tatttattag tatcttcttt agctatcttt tgaacaccta atacagttgt tttatactca
    20461 ttataagtat ctattaattg ttttaagcac ggaacatctg aatctactat atcatcacct
    20521 aataatacgg caaaaggttc atcacctata aaactttttg cacagtaaat tgcatgtcca
    20581 agaccttttg gctctttttg tcttatataa tgaatattta ccatatttga tatgtctctt
    20641 accatttcta acatctctgt cttacctttt tgctctagtt ctaactctaa ttcaactgat
    20701 ttatcaaaat gatcttctat agatttttta tttctacctg ttattataag aatttcttca
    20761 attcccgatt ctatagcttc ttctattata tactgtaaag ttggtttatc tactatagga
    20821 agcatttctt tgggctgtga ttttgttgct ggtaaaaatc tagttcctag ccctgctgct
    20881 ggtattattg cttttttaac tgtcatctgc attttttcac ccttcttcgt aaattttcta
    20941 ttgtaccaaa ttaatatacc atatttatac tttttcttca aactctatat tatcccaata
    21001 tttaatgcta taagataata taaggtagat gaaatttcat ctacctttag ttttataagt
    21061 taatattgta ttgtttatat tttatccaaa acttatacag gtactaaatt tcatctaaga
    21121 tgccttttat atcactatct atatcttcat ctagataaga atctaaatct tctaagtcaa
    21181 cttctagttc ttgatatgtc atatcaacac tgacatcctc atctatatcc atttctgata
    21241 ttaattctcc taaaatacta tttccatcag aatctaaacc actatctata tcttcatcta
    21301 tatagttttc atttaaaatt tcatctaaat caatctcgta ataaacttca ttattttttt
    21361 catcccctga gtccaatcct aagaactcat agttaaaagt ccaaacattg tatttacttg
    21421 acatacttta ttcctcctgt gaaaaacata ttttcatcta gtttattggt tccataatca
    21481 acagagttat atattttttc aattatgtct tttcttcttt cttttgtact attatttaat
    21541 gtcaattgtt taaatacata tgtatttgtt attctctcga ataatatttc ttttatacta
    21601 tcatcatcaa tatttctata gtttttccac aataactcaa ataacttaaa catttcccta
    21661 ctagtttcat ctacataata aggatacata ttttctacta aatggtttaa tcttgatatg
    21721 gcttgtttta aaaatacatc aagacttgca ctttcacttt cttttaacat tctataattg
    21781 tatttcttct tatcttctcc tgaaattaca aagatgatat tgtctaaact tttttcaact
    21841 tcatttaaat aactgcttat attatatgat aaatcagaca atagattttt aatctgctta
    21901 aacacttgta catcaagttt agtattatac ttttcaaaca aatctatttc ttgattttct
    21961 aatattcttg gcatatatgc tgacaataaa tctaaattgt ttctttgttc ttgtatttgc
    22021 ttataaagtg aatttataac ttctattctt atttcatcat ttaactcttt ttctaaaatc
    22081 ttatcaaatt cagatttcat atagtaaata tttccaaaga aattaaatat tatcatatca
    22141 ttcatagctt tagaccaatt cttatatatc acttcaatag aattttcttt aagtagaggt
    22201 tgctttgcat atataaatac atcttgcata agtttttgaa ccatactttt acttaagttt
    22261 aaaagtactt tttgattatt aaattttatt tccgtttcta caaaattaga attttcgttt
    22321 tcaagttctt tattaattac aatgtctttt atatcactat tttttataga tatgatttct
    22381 ttttgaaaag actttagaat agtcaagcta tcgaaatctt cttgaataaa aaatggagca
    22441 tgttttaatg tatatcccac tatttcattt tctatatctt ttaggtcatc tatttgcata
    22501 atttctctat ttttatcatt tatatgtagg ttaaatacat ttttattatc atataatatt
    22561 atatcttctc ctaaatttaa cttagaacaa ttatctttcg ctgactttac aatagtcttc
    22621 ttagatttct tatttataaa aattaattgg tcttgatatt ttactaaaag catgtttgtg
    22681 tttttataat caaatccatc tatatttcct gatatcttgc agaatactat ttcacaatct
    22741 ttaggaagat ttcctatttt ttggttatcc ttaactctct catttaaatc agatgggact
    22801 acactatcta tattgttatt aaatatagat acagacctta ctataatccc ctctctttcc
    22861 atatgaaagt atcccttcaa tgacactctt ttatcttcta aaatgtatct ttctatatca
    22921 tcaaaattta tttcaaatct atttttccca ctgataaata taaacttctc attatcttta
    22981 ttaattccac ccatataaaa cttattgtca tctaaactta atatagtcat attatccttt
    23041 agatagaata taaattctct ttgacttttg cagattaaat catattcatc caaagttatt
    23101 ttcatagtca aatttgctgt aacattttta cttgaatttt cactttttat gtaaaaaggc
    23161 aagttatttc catagataat tatttgagaa tcttctaaaa ctgcctctaa tttttcttta
    23221 ttgtctgaaa aactatatat atattttaca cctgtatcct tattaacttc atctgatttg
    23281 ctgattatta tattccctag atttgttata tgaagctttt tatattcttt tgagtatcta
    23341 cttatgccac taagctcaaa cccatctgaa agctcatata tgattttttc tcctaatttc
    23401 aacatacctt caccacctaa acagaattat aagtatttta taaaggtgaa caaaatgtct
    23461 cacaataaat aatatttttt ttaatacttt ttattctgag acatagtttc tccttttcta
    23521 taatgctcta agcaccttca actatttctt cataaagttt atctaaatgt ttaacatatt
    23581 cacgatatcc agatttgttc tttaactcac ttcttaaatc ttcatatttt tgtttaagtt
    23641 cttcagcact caaagaagga gctgattctt ttaattcttc taacttataa tcatagtact
    23701 tatcatacat agctatatat gtatcaatag atttcttagc tagttcatta catttttctt
    23761 gtgcttctcc atattgagaa taatcaccta tttttatttt atagtatcca ttttcttgaa
    23821 ttattgttga agaaatacct ttagcctcat attcttttgc tgtttctttt gctgtttttt
    23881 caactttaag tgaacctgca taaacagtgt aatatacacc tttaccatct ttatatgctt
    23941 ccatttcttt tgctttcttt tcagcttgtg ctttttcttg agcctctttt tctgcttttg
    24001 ccttttcttc tgcttctttt ttctcttttt cagcttgtgc ttttttctct tcttcagtta
    24061 atttattgtt agcttgttgt tgagttgatg actttggaat attctcttta tcatttttct
    24121 tattgttgcc tactgttata aaatatccta caccaacaat aaccactata actactgcta
    24181 taatagtttc ttttaatcta ctcttcttag aaacaacctc ttcatcatct aaagaatctt
    24241 ctttatctga tacataattt ttcatttctt tcttgttttc tctatatttg tccttagaag
    24301 aatttttaga ttttttatta ctattttctt tctttttaat aggtattact actgattttt
    24361 cattttctaa tttttcttct tttatttctt ttgctttttt atcttctaag tttttacttt
    24421 ctttttcaag cttcgattca ttatttgaag atactttttc atctaagtta ttatttattg
    24481 gtttttctat ttttacatta cgttcttctt ctatatgttg acttggttct tcttgtttta
    24541 tttcttttaa ttcattttgc tctatttctt ctgattttac ttgatgattt tcaactggtt
    24601 tatctaaaat tatatcagga gaaatatcat ttaaattctc ttcttcttgt tcaacttctt
    24661 cattgtcttt tttaataaat ccaaataatt tagccttctt tttactcttt ttattttctg
    24721 gttcaattat atcttcttta ttgctgtcgt actctttatc tgtagtatct ttatcttcta
    24781 caacgtcacc tatatcttga ttattactat ctatttcttc tttaacccct tcttcagcat
    24841 catcttctat tgaaatacta cttctaaagc aaatatcttt atctgcattt tttatcatgt
    24901 aaatgtattc ttcaatatcg atatctttat ttcttctagt tctttttgat gcaatttcat
    24961 gattttctaa ttcactatag ttatctttta ttagattctg tgctttattc catgtatctt
    25021 cactaatttc tgttttattt ttaattacat agtccacaaa ttccttaaaa ttttcaggac
    25081 caaattctcc aattatagtc agtctcattg caccttctat aaggtctcta tttcttctct
    25141 ttaaaaattc taatacaacc gttgcacaag caaaatcttt aataatttct ttgccaaaac
    25201 catatccttc aacagaatga agttcttcta atccacataa cttcttatat tcattgtgta
    25261 ttgtttgaga tacactttca ttatttaagc tatttaactt atctataaac ttcgattcta
    25321 tatcatttga ttttgattca tgttttactt ttgaattttt aatttcattt aatagcatgt
    25381 cattttctga attatcttta cctaattgca aatcctcaat ttcagttgct tttatttcta
    25441 ctttgtcttg ttcgttattc tcttccacat tattaggtac cacatcttta ttgctagcta
    25501 atattttgtt tacacagaat ataatttctc tttttaattc tcttttcgca tctgcttgat
    25561 ttttaagaaa taaatctcca cattctttct tttctaaact tatttttcta agagatatat
    25621 taagaagatc tttatatagg tttaaaacct tataatcctt ttctaaacgt cttcttctct
    25681 ctgatagttc cattttatca taagctaaaa aactatttaa atcattggct tttagagagt
    25741 ctaatccctc tttcatagcc ttatttacat actttctaca ttttgctgta gttaattcta
    25801 aatctttttc taattcatct atttcaggta tgtacttatc tactatccat ttgccaataa
    25861 gtggttctgt atttcttgct aatgtcttat aaaacaatat attaaatttt aaaagctctg
    25921 catattttgc ttcattaaat tctacttttt caaatttctt ttccaaaaca ccatctagct
    25981 tttcatttat tttagactct tgttttaaaa aacttgctgt gacatttaaa acagtgtttc
    26041 ttattatatt attttcactc aaaaccttca ctccttaaat caattatttt attgtaatat
    26101 ttacattgtg caaagttgct aatttgatta tgatatctaa ataattattt actaaatttg
    26161 ctacatctta tatcatatca tattatttac atcattttac tttttctttt tatatctatc
    26221 ttatattata ccatttttaa tatctgtact aacttatatt acaatattcc tcaaaatttt
    26281 aaaagtagat tagacaaatt tacaaataaa aaaacatcag tttaaactga tgtttttgac
    26341 tatcgaaata attaagcaag tctataagcg gagttctgta ttagataatc atctttctag
    26401 gcctattgtc accaataggc tcaagcgacc tacctaccgg agagtacgag cagcactctt
    26461 tattcctatc ttggtcttgc tccaggtggg gtttacatag ccaactagtc gcctagctgc
    26521 tggtgagctc ttacctcgcc tttccatcct taccacaata gtggcggttt atttctgttg
    26581 cactatcctt aggatcgctc ccactaggcg ttacctagca ccctgctcta tggagctccg
    26641 actttcctca tgtaagatta catgcgatta tctggcttac ttaatattta ttttacttag
    26701 ttatgttaac acaaattctt ttacatgtca aagtaatatt atactaaaaa tttaaattta
    26761 ttcaaaaata gtgtaatata gatatataaa ctacatttaa ctcgaggtga tatattgaaa
    26821 aaattatata gaatagtaat taacattata ctagtattag taatacttta cagtggattt
    26881 aatatatact caaaacttac caaatacaat catgatacta aaatatcctc agaacttcaa
    26941 aaaaaagaat ataaaaaaga ggatttatca aatattaaca gtgattttaa attttggctt
    27001 tctgttgaga atacaaatat aaattatcca gttgtacaat ctaaagataa ttcttactat
    27061 cttgacaaag atttttataa aaaagattct atttctggta cactgtttat ggattataga
    27121 aataaatcta ttgatgacaa aaatatcata atatatggac ataatatgaa aaataaaact
    27181 atgttcaaca acctaaataa gtttaaagat gctgacttct ttaaaaaaaa taataaaata
    27241 aaaataacct tgaatggaaa agaattttta tatgatgttt tttctgctta tattgtagaa
    27301 tctgattatg attatctaaa aacaaatttt aacaatgaat ctgattatca aaattacata
    27361 aatgatatta cttctaaatc attgtataaa tctcctatta aggtaaatag caatgataaa
    27421 atagttacac tttctacatg tacctatgaa tttgatgatg ccagaatggt gattcatggt
    27481 agattgattt aaaactcaca gacacagttt aaaacaataa ttttaaactg tgtcatcttt
    27541 tatacctata atttgtaaat tagaccacta aaagtattta atacaaaata acaaatacat
    27601 caaacaataa aaaacaataa aaaaagacta tgctaaaaac atagtcttta ctggagctgg
    27661 tgataggaat cgaacctaca acctgctgat tacaagtcag ctgctctacc gttgagccac
    27721 accagcacac ctattttatt gtaaattagc aaaactaatt tttaaaagtt aacactctaa
    27781 aaactacaca tatatcttaa tgaatgaa
//
LOCUS       DAMKNB010000046        27357 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.048, whole genome shotgun sequence.
ACCESSION   DAMKNB010000046 DAMKNB010000000
VERSION     DAMKNB010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 27357)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27357)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27357
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.048"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            265..798
                     /gene="pyrR"
                     /locus_tag="PC494_002225"
     CDS             265..798
                     /gene="pyrR"
                     /locus_tag="PC494_002225"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001156491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HDF3912722.1"
                     /translation="MVEKAQLMDEKAIARAITRISHEIIERNKGVENLVLVGIKTRGV
                     PIANRISKKIEQIEGTKVDTGDIDITLYRDDLEKIHVEPVVKGTYLDFNVNDKTVVLV
                     DDVLYTGRTVRASLDAIIDIGRPKSIQLAVLVDRGHRELPIRADYVGKNVPTSRHEII
                     SVSLLEIDGEDSVTIKE"
     gene            1082..2293
                     /locus_tag="PC494_002226"
     CDS             1082..2293
                     /locus_tag="PC494_002226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HDF3912723.1"
                     /translation="MKKTIMSLQHLLAMFGATVLVPILTGFNPSVAIFCAGVGTLIFH
                     FCTEGKVPAFLGSSFAFIPVILAAKEAYGGDLAYAQGGIIVAGLIYIIMSIIVKIVGV
                     NKIKLYFPAQVTGAMIVVIGLNLLPTAFSMASANFVIASITLAIAILTNKFGRGFIKQ
                     LGILIAVFSGYIICLILRLVDITTITEASLFAIPNFTVPKFSLGAIVIISPVVLAVFM
                     EHIGDMTTNGAVVGKNFIENPGLNRTLLGDGFATIVAGCLGGPANTTYGENTAVLAIT
                     KNYDPSILRRTAIFAILLACVGKFGGFLQSIPGSVMGGISIMLFSMITYVGLKTIRDS
                     SCVESKINILIIAVILLIGLGTTYLSNKGISIGIPITSTVKITGLSLAAIVGIVLNRI
                     LNNQDFKVEEE"
     gene            2592..4244
                     /gene="abc-f"
                     /locus_tag="PC494_002227"
     CDS             2592..4244
                     /gene="abc-f"
                     /locus_tag="PC494_002227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein"
                     /protein_id="HDF3912724.1"
                     /translation="MLLVKVENLKKYYADKLILDIDKLEILENDKIGLVGSNGQGKTT
                     LLKAILGEIEIDEGYTYLTESYSYISQSENNIETCSHSKEKSLLNAPDKFEEHLSGGE
                     KVKLKIADALSNKKNIIIADEPTSNLDKKSIGVLEDMFKRHEGALLLISHDRRFLDEL
                     CTTILELEDGKLKAYKGNYTDYLMQKDEEVKRADFEYQEYVKEKKRLEKALLYKKALS
                     DGIRKTPKRMGNSEARLHKMGGQTNKKKLDSNVKAIKSRIDKLEVKNKPKVSKEMNIK
                     IQDGMEIISKNLVEVKDMTLKLENKLLLDNVSFKIKRGKKIALLGDNGCGKSTLIKEI
                     LADKNDNIKINNKVKVGYFDQNQSLLDEEKSVLYNTKVNSSFDESFIRINLSLFGFKG
                     DDVYKKVKVLSGGEKVKIALCKIILEDNNFLVFDEPTNYLDIKSMEALEKALINTDKT
                     MLIVSHDRVFVSHICNYIIEIKDAKIREFDCNYDEYTISRNKKTPSRENQIKKENLLV
                     LENRLTTVISMLSIEKDNLKKELYESEYNELLKQINKLKNSF"
     gene            complement(4459..6234)
                     /locus_tag="PC494_002228"
     CDS             complement(4459..6234)
                     /locus_tag="PC494_002228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NFACT family protein"
                     /protein_id="HDF3912725.1"
                     /translation="MALDGLVIHSIVDELSSKLTGGKIDKIHQPEDDEVIFNIRNNKE
                     NFRLVLSASASNPRVYLTSNYQKENPLKAPMFCMLLRKYIQGGNIVEISQIGFERIIK
                     ISVESLDELKEKTVKNIMIEIMGRHSNIIITHGEENKIIDSIKRVPFSISRVRQVLPG
                     HDYSLPPEQNKLNPLDDISKDLFIKNLEELEGPIFKSIYSKFLGISPIIAKEICYRAG
                     VNQNAIIKDISDEQFDSLHKVFCNLFNDINSNKYSPCIIIDKKVDKVVDFSCINLTLF
                     SDLSYINKDSMSRILEDFYRTKDIKDRINQRSSDLKKSISVKLDRLYNKLKKQEEELS
                     ESENADIYKIKGELITSYIYMVEKGMESIEVANFYDENCNDVTIELNKNLTPSENAQK
                     YFKKYNKMKHAKVEISHQISLNKEEIDYLENIILSIENCENLAELQDIKEELAKVGYI
                     KTQKKNSKKDTIPSTKPHEFVSSDGFKILVGKNNKQNDYLTLRLADNDDLWMHTKNIP
                     GSHVIIKCAGKEVPDNTVFEGAMLAAFFSKSKLSSQVPVDYTKRKNVKKPSGSKPGMV
                     IYETNSTIYVTPEEETVAKLKVKSE"
     gene            6530..7564
                     /gene="ltaE"
                     /locus_tag="PC494_002229"
     CDS             6530..7564
                     /gene="ltaE"
                     /locus_tag="PC494_002229"
                     /EC_number="4.1.2.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low-specificity L-threonine aldolase"
                     /protein_id="HDF3912726.1"
                     /translation="MRFIDLRSDTVTMPTDEMREAMAKAPVGDSIFRDDPTVNKLEEL
                     AAAKVGKEDAIFLPSGTFGNQLALFTHCLRGQEIIIGKGYHIVTHEVGAPAVIAGVQL
                     RTIDEDESGALNPELVEKAIRRDDIHEPQTGLICVENAYSGGTVVSLDNLREIKKIAE
                     KHNLPVHLDGARLFNAALTLGVEAKEIAKCCDSVMFCVSKGLAAPMGSILAGNKEFIA
                     KARRKQKVMGGGMRQVGIVAAAGIIAIEKMTLRLNEDHENAKYLACELNKIDGIEVNN
                     VNPDISMVFFKMSEDIIKEDVLIKEFFERNIKINKMENGEYRFVTHVDITKEDLDYVL
                     KTLKELIGVC"
     gene            7851..8681
                     /locus_tag="PC494_002230"
     CDS             7851..8681
                     /locus_tag="PC494_002230"
                     /EC_number="5.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate epimerase"
                     /protein_id="HDF3912727.1"
                     /translation="MKFWKLHGIGNDFIAIDGRFDQINPSDYTALAKKVCHRRFSVGA
                     DGLLVVKDSKVADVEMVYYNSDGSRAAMCGNGLRCFCKFVYDNCIVKKESFTVDTLDG
                     IKDIKVNLTNREINSIRVNMGKGSFIAKDVPVLTNKERFVQESIKVLDRELKVTSMLM
                     GVPHTVVIVDELDVDDVCKYGKEIENNKIFPEKTNVNFVKVEDKYNIHVYTWERGCGY
                     TLGCGTGMTASAIVCNLLNMVESSVNVTSQGGTVKIDVGDFSYMTGPAVKICEGILEV
                     "
     gene            8685..9566
                     /locus_tag="PC494_002231"
     CDS             8685..9566
                     /locus_tag="PC494_002231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YicC family protein"
                     /protein_id="HDF3912728.1"
                     /translation="MAISMTGFGRGEYKDDNYYFLVECKTINHKYSDINIRLPRKISF
                     LEDKVRNLVKNYVKRGRVDLYIKFDLLGKEDVNLNFDEGLASQYIDILKEIKNKFDII
                     DDISVMNVAKFPDIVKIEEKEEDEDLLWSMLNQAVEDALIKLREMRSEEGKKLAEDIA
                     MRCDLLKNHIEEIEKYSSSVVEDYREKLNLRISELLDDPSIIDENRLAQEVAIYADKS
                     SITEEIVRFKSHIGQLKNTIFKDDSIGRKIDFLIQEMNRETNTIGSKSSDINITNLVV
                     EVKSELEKIREQIQNIE"
     gene            9596..10213
                     /gene="gmk"
                     /locus_tag="PC494_002232"
     CDS             9596..10213
                     /gene="gmk"
                     /locus_tag="PC494_002232"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HDF3912729.1"
                     /translation="MFVKKGLLLVVSGPSGAGKGTICKELLKENDTIKLSVSATTRKP
                     RTGEVDGVNYFFISKEKFEEMIEKGEFLEYAQIYDNFYGTPKAAIMECLEKGQDVLLE
                     IEMQGAKQIKEVCPEGVFIFVLPPSLKELKNRIVGRGTETEAEIEKRFSCAYEEIKMI
                     KDYDYFIFNEDVKTSAKEIEGIISSEKNKVSRYKNIIIEKFKEEL"
     gene            10216..10482
                     /locus_tag="PC494_002233"
     CDS             10216..10482
                     /locus_tag="PC494_002233"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HDF3912730.1"
                     /translation="MLKPSINEVLEKIDNRYYLVGTVSKRARKLIDGEEPYVSNKTKE
                     KPVCVATKEVASGKITYRLLTEEEIEIEEARHHAEQHQQISEEE"
     gene            10487..11686
                     /gene="coaBC"
                     /locus_tag="PC494_002234"
     CDS             10487..11686
                     /gene="coaBC"
                     /locus_tag="PC494_002234"
                     /EC_number="4.1.1.36"
                     /EC_number="6.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional phosphopantothenoylcysteine
                     decarboxylase/phosphopantothenate--cysteine ligase CoaBC"
                     /protein_id="HDF3912731.1"
                     /translation="MLKDKTVVIGISGGIAAYKACDVVSKLKKLNANIHVIMTKSATE
                     FVKPLTFQSLSQNYVVEDMFEEPKTWEVEHISLAKKADLFLIVPASANVIGKIANGIA
                     DDMLTTTVMATKAQVLIAPAMNTNMYENPIVQKNIQTLKSFGYKFIEPESGRLACGDI
                     GTGKLANPDIIVEEVLTNLTKEQDLKGQSMIVTAGPTVESIDPVRYLTNRSSGKMGYS
                     IAREAIARGADVTLISGPTNLSIPQNLKKFVQIESAQDLYEAVVSNLSENKIVIQSAA
                     VADYKPKTYSDKKIKKKNDDLSIELSRNYDIAYEIGKIKEDKILIGFAAETNDLIEHA
                     KGKIKKKNLDFIVANDLTKEGAGFRADTNIVKIIDVEGNITEYPKMKKEEVANVILDK
                     VKALLEK"
     gene            11925..14450
                     /gene="priA"
                     /locus_tag="PC494_002235"
     CDS             11925..14450
                     /gene="priA"
                     /locus_tag="PC494_002235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HDF3912732.1"
                     /translation="MNNILNLSRGFIMKKYAKVIVRSNTIYTDNLFTYQIPVFLSDVI
                     KIGHRILVPFGKGNKPTEAFVFQFTDSLDEKIKIKEIIDILDENPIFRKEDLELVYWM
                     KNRYLCTYIECINLIYPKGYKLNNYKVVLLGESLSGLNDIELKEKISTLSDKNREIVE
                     KVIDSKGKIKVDKLKYIPNLNSSLYTMNKNGIIKLCWEYKNHKNEKKVCYISLSLESD
                     KIDDYIEQNKINVGSKQKEILSFLKNNENVEINDLLDLLNASKQSINSLSKKKLITLE
                     FKDYYREPKSIYKSVLKSIKLNNEQQEAVDEIKSNMFVDDKKPYLIHGVTGSGKTEVY
                     MEIIEFALNQGLDSIFLVPEIALTPQTIDRLKSRFGDLVGVFHSKLSEGEKHDVYKAV
                     KAGKVRVLIGARSALFAPFNSLGLIIIDECHESSYKSEKNPKFNAIEVARFMALKNNI
                     TLILGSATPSIEEYYRAKSGEYKLINIKSRANDKPLPNIEVVDMKDELDKGNRSIFSL
                     KLQKEIRYAIEENNQVILFLNRRGYANFVSCRKCGYVFQCENCDISLTYHKKSNTGRC
                     HYCGYEKEIPKECPECKSTYVKPFGVGTQKIEEELKYIFPDIKTLRMDKDTTSKKGAL
                     DEILNKFKDKEADVLIGTQMLSKGLDFENVTLVGILSADMILNFPDFKSFETTFQLIT
                     QVSGRAGRADKEGKVVLQTYDTEHYAIKHAIEYDYEGFYEDEIKIRKAFGYSPFNNML
                     SVVVSGEDERLVIKNIKNMHASLIYLLEKRGINDLGFILGPNPCSISKINQNYRWQIL
                     FKDENIEINLLKGIIKYICITKRDLIFDKNINVSIDINPNSVL"
     gene            14468..14908
                     /gene="def"
                     /locus_tag="PC494_002236"
     CDS             14468..14908
                     /gene="def"
                     /locus_tag="PC494_002236"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HDF3912733.1"
                     /translation="MALRQIVQIGEPVLRKKSKKVEKIDEKIIQLLDDMAETMYDADG
                     VGLAAPQVGILKRVVVIDIGEELIELINPEIIETSGEQIDEEGCLSVVGEAGNVRRPN
                     YVKVRALNRNGETIELEGEELLARAFCHEIDHLDGILFVDKIEK"
     gene            14923..15852
                     /locus_tag="PC494_002237"
     CDS             14923..15852
                     /locus_tag="PC494_002237"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HDF3912734.1"
                     /translation="MKIVFMGTPDIAVPCLQKIIDEKYEILGVVTQPDKPKGRGKKLG
                     MSPVKELAIENNIPVYQPVKARDKEFIDKIKSLNPDVIVVVAFGQILPKEILEIPKLG
                     CINVHVSLLPKYRGAAPINWVIINGEEKTGVTTMYMDEGLDTGDMILKTEVNLDENIT
                     AGELHDKMMNIGAETLKETLRLIEEGNAPREVQNHEEFSYAPIMNKSLGNIDFSKSAR
                     EIHNLVRGVNPWPSAYTTYNDVIMKVWKTKVLDEKSTKDVGTIIDVSKDGIKVSTIDN
                     VLLIEEIQMPNKKRMLVGEYIKGNTIETGLVLG"
     gene            15862..16614
                     /locus_tag="PC494_002238"
     CDS             15862..16614
                     /locus_tag="PC494_002238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF116 domain-containing protein"
                     /protein_id="HDF3912735.1"
                     /translation="MTDIKKYLTSVGILILILGILIGVVNFFIISLTQIFSLMINIII
                     ISLILIILCSTAVTYRVIKGKYVNSNIMKINFNIVSGLFPIISFIASSFGMSKSDIRR
                     IYIKLNNEYIYSNKYNFNPEDIIILIPHCIQENSCKLKVTNDIDNCKECGRCNIGELI
                     KLKEKTNVKIFVATGGTLARKIIMDNKPKAVVAVACERDLTSGIQDIKKIPVLGVFNK
                     RPNGPCVNTNVDIMDIEKAIGFLTGKNILVCN"
     gene            16683..17384
                     /locus_tag="PC494_002239"
     CDS             16683..17384
                     /locus_tag="PC494_002239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metallopeptidase"
                     /protein_id="HDF3912736.1"
                     /translation="MYPVYGGFWGFDPTMVVLIPAILLTIYAQFKVSSTTNKYLRVNT
                     RRGYTGEQTARRVLDSNGLYDVKIEMVRGHLSDHYDPRRKAVRLSEDVYYGTSITSVA
                     VAAHECGHAIQHAKGYAPLQIRSSLVPVVNFASSISWFLIFLGFIMAGPFLKIGILLF
                     SASVLFQIITLPVEFNASSRAIVQLGNLGIIDESESRQSRRVLSAAALTYVAAALVSI
                     LQLLRLLLIAQRRND"
     gene            17446..18771
                     /gene="rsmB"
                     /locus_tag="PC494_002240"
     CDS             17446..18771
                     /gene="rsmB"
                     /locus_tag="PC494_002240"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HDF3912737.1"
                     /translation="MDAREVGFKVLCDIEKNDNYSNIAINKHFKNLEISDMDRGLATE
                     LIYGVIENKYYLDYIINKLSKIKVKKMSTYVKIFLRMGTYQILFLDSISDYAAVNETV
                     KLSKKYDKKSSGFINAILRNEIRAKETIMDITEEDSVKYLSIKYSYNSWIIKNWIDKF
                     GQEFAEDLLEANNEKPSIYIRTNTLKISREELIEKLSEMGIVCLKVPMVEEAIKVEKM
                     KNIEKNELFKAGLFTIQDISSMIVGKVINPKEGSFVLDVCSAPGGKSTHLATLMNNTG
                     QVVARDIFEHKLKLINSTVNRLGLKNVFVERFDASEIDENSISKFDYVLADVPCSGFG
                     IIRRKPEIKYKKEEELKDITSIQKKILENASKYVKVGGTLVYSTCTIQDVENINIVTS
                     FVEENHNFEFVPIDTVNVDLDNQDKGYLKIYPNIHGIDGFFIAKLKRIR"
     gene            18779..19810
                     /gene="rlmN"
                     /locus_tag="PC494_002241"
     CDS             18779..19810
                     /gene="rlmN"
                     /locus_tag="PC494_002241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HDF3912738.1"
                     /translation="MEKKKIVLKNFTEDELKEFMKTIDEKPFRGSQIFSWIYKGAKTF
                     DDMNNIPKSLRNKLEEVSCIGHIDIELKLESKVDNTKKYLFLLDDGNIIETVMMDYDS
                     RVTVCVSNQVGCRMGCNFCASTMDGLIRNLEPWEILDQVIKIQEDTGKRVSNLVLMGS
                     GEPLDNFENTKQFLKIINEKNGLNIGYRHITLSTCGIVPKMYELADLEIAINLALSLH
                     SPYDEERRKIMPVANAYSIEEILNACRYYIKKTNRRVTFEYSLIKGVNDSEKEAKALA
                     KLLKGMLCHVNLIPINKVEEREYEKPDKAFIYKFRDSLEKNNIPATVRMSMGSDISGA
                     CGQLRRKYK"
     gene            19830..20582
                     /locus_tag="PC494_002242"
     CDS             19830..20582
                     /locus_tag="PC494_002242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HDF3912739.1"
                     /translation="MVYSCASHIGKIRKNNEDYCEGEVIDTEHGPIGIFAIADGMGGH
                     KKGEVASKLAVENIIDFLKENLLQHDNVKIDYIDDILKQAYNNVNSIVHKKSMEDIEF
                     EGMGTTLVTAIVYNNVLYVANVGDSRCYLLTDEKFDKITIDHSVVEELMMAHVITEEE
                     ARRHPQRNRITRAIGTDDMVVVDIFKKEIKKSDIILLATDGLTGFIDDEDIRDLILDY
                     EYERTSNISEELISMANDVSGKDNVSVIVIKV"
     gene            20599..22614
                     /gene="pknB"
                     /locus_tag="PC494_002243"
     CDS             20599..22614
                     /gene="pknB"
                     /locus_tag="PC494_002243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HDF3912740.1"
                     /translation="MGDTILGNRYEIIRKIGDGGMAFVYEAKDRLLNRTVALKVLRPE
                     FVDDDEFLTKFKREAEAVASLSHPNIVNVYDVGEDGKVHYIVMEFVDGKNLKEIIQDE
                     GILDEYTALDITKQIAMALSAAHKKGIIHRDIKPHNILISNEGRVVKVADFGIAKAVS
                     NSTMTNIGSIIGSVHYFSPEQAKGKFVTNNADLYSLGIVLYEMLIGKVPFRGDSPISI
                     ALQHINDDIDFTSEEKVRIPQSVRTTIKKLTEKSSADRYQTAEELIEDIEYIEKNIDL
                     DFIKEYDDFATKKIDEKEINKVVNPTLAKPAPEKVVKPVEVADLDDDEDYYDDFYEED
                     DDEDEEEEEIMRAKKNQRPKSTPSKRTKKKKKKQESPKSRRRLKVIAAVLILILCAQV
                     FLAYKFLFAGGFGNKSLTVPNLVNMTLEEAQSAVEKEGLYLSVKSEEYNSEVDENCII
                     SQTPEGGSTNVKKGDTINVVVSKGSSQASVPNVVGLTLSNAKQLIEENNLKVGTVKYE
                     YSSIYKEGTVLSQSPGAGSSRAQEGDEVNLYVSKGSEKSNTQTPTVPDKKPTTPENNT
                     PTEPGSNSGNSGGNSGGSNSGNSGGNSGNNGSNSGGSNSGNSGGNSGGSNSGDNGGSS
                     GGSNSGDNGGSSGGSNSGDNGDSSGGSNSGDNGGTSSGTGANIGKTE"
     gene            22722..23459
                     /locus_tag="PC494_002244"
     CDS             22722..23459
                     /locus_tag="PC494_002244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HDF3912741.1"
                     /translation="MKKKTVLITGGARGIGKAMSKAFAKEGYNVLVNFNKSENEAKEL
                     YTILNEKNFSVKLFKADISNREDVEDMVDYCIKEFGGLDVLVNNAGVSQDKLFTDITD
                     EDWDNMMNINLKGSFYCSQVALKYMISEKKGNIINISSIWGISGASCEVHYSITKAGI
                     IGMTKALAKEVGPSNIRVNSIAPGVINTDMLSGYNEEDIDALVEETPLMRLGTPEDIA
                     NCAIFLASDKSNFITGQVISPNGGFVI"
     gene            23557..24441
                     /gene="rsgA"
                     /locus_tag="PC494_002245"
     CDS             23557..24441
                     /gene="rsgA"
                     /locus_tag="PC494_002245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HDF3912742.1"
                     /translation="MLEGKIIKGISGFYYVDTYNGIYECKARGIFRKQKITPLVGDRV
                     KISIVDENEKKGILEEIDSRDTELIRPPIANVDKALIVFAIKNPKPNLSLLDRFIVLA
                     EKENLETVIILTKADLDDNDTLETVKNIYELSGYKVIPVSNITKLNIDKVKEELKENV
                     VVFAGPSGVGKSSLLNEIDENFKLQTGVVSDKIKRGKHTTRHAELLKLEFGGMVADTP
                     GFSSLALEDIEEVELKDYFIEFDKFNDCKFGSKCIHENEPNCAIKEAVTNGEISKERY
                     DSYIQLLHEIRQNNSRRY"
     gene            24446..25117
                     /locus_tag="PC494_002246"
     CDS             24446..25117
                     /locus_tag="PC494_002246"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HDF3912743.1"
                     /translation="MIKLAPSILSADFAKLLEDVRKVESAGCEYLHIDVMDGHFVPNI
                     TLGPLVVKSLKKENINMVFDAHLMIENPDQYIEEFVKAGCDIITVHQEACVHLHRTIQ
                     NIKSHGIKAGVVLNPATPVDTIKHVLPDLDMVLLMSVNPGFGGQSFIPCVLDKIKELK
                     AIIDSQGLNIDIEVDGGISPKNVAEVVQAGANVIVAGSAIFGSDDIQETVNLFRKNAS
                     LEELV"
     gene            25126..25767
                     /locus_tag="PC494_002247"
     CDS             25126..25767
                     /locus_tag="PC494_002247"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HDF3912744.1"
                     /translation="MKICIVLNGEIEDYEVTRDIIIKECYDCIICADGGANHTYKMEI
                     MPDYILGDLDSVEEEKINFYKNKGVKFEKFPSKKDETDTELCLFLAKTLKANHIDFFG
                     ALGGRIDHTLANIKLLYYLKEDGIYSRILSDKEEMYIVENEEISLYGNPGDTISVIAI
                     NGDAKGVTLTGLEYPLDNYYMKYSVPIGISNVMLSNSCKIKVEQGCVLVVRNL"
     gene            25898..26527
                     /locus_tag="PC494_002248"
     CDS             25898..26527
                     /locus_tag="PC494_002248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HDF3912745.1"
                     /translation="MVDSIIFDLDGTLWDSTEEVCKVWQDVLSEHKEIELSVTKDLFR
                     SLMGLSFEEIANRLFPNLSEEERMNLLNECSLKECDYLSENGAKLFDDIEDTLKLLSK
                     KYKLFIVSNCQVGYIESFLKAHKLEQYFIDFECPGNTGLHKGENNKLIIERNKLINPI
                     YVGDTQGDANSAKFVGIPFIYAKYGFGNVDVYDYFIDSFKDLLEHDILK"
     gene            26582..27238
                     /locus_tag="PC494_002249"
     CDS             26582..27238
                     /locus_tag="PC494_002249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HDF3912746.1"
                     /translation="MELQDTIFKRQSVRKFKNQDVSDEDILKMIKAAGAAPSGKNIQN
                     WHFVVIKRRDLMEKIADVITKKQQEILVEMDKVSVDKANRFRKFVKNFTLFYLKAPVL
                     VLVFTKVYNPSGYYELELIDAPKETIDKLFIRNPGMQSLGAAIENFTLSAIELGYGSC
                     WLTSQNYAADEIEAVLEAETGFEKGEYFLGAMLALGVPEDNLKSPSKKPVEEICTFIK
                     "
BASE COUNT        10896 a         2772 c         5094 g         8595 t
ORIGIN      
        1 tttaaaaaag cttgaaaaat ttgaaatata aatatataat ttgatttgat agattaaaaa
       61 attatcttta aacgatacag agatatcgta agacaattgc taaattgcac tgtatatttt
      121 ttatataaga gcttcttgtc ttgtgatgag aagttttttt gttgtttaaa ttgaaatttt
      181 aaataaaaat aaatttataa aaaattaaaa gaaaggagta gatttgtcaa atagatatat
      241 tatatctttg acaataatta tgatatggta gaaaaagctc aattaatgga tgaaaaggca
      301 atagcaagag caattactag aataagtcat gaaataattg aaagaaataa aggtgtagaa
      361 aatctagttt tagttggaat aaagactaga ggtgtgccaa ttgcaaatag aatttctaag
      421 aaaatagaac aaatagaagg aacaaaagta gatacaggag atattgatat aactttgtat
      481 agagatgatt tggaaaaaat tcatgttgaa cctgtagtta aaggaactta tttagatttt
      541 aatgtaaatg ataagacagt agttttagtt gatgatgttt tatacactgg aagaactgtg
      601 agagcttcac tagatgctat tatagatata ggaagaccta aatcaataca attagcagtg
      661 ctagtggaca gagggcatag agagttgcct ataagagcag attatgtagg aaaaaatgta
      721 cctacttcta gacatgaaat tatatctgtc agtttattag aaattgatgg agaagattca
      781 gttacaatca aagaataatt atttttaagt attatataaa agcttagcat tgaatagtca
      841 gggaggagga taaagcttac atagattgca caaaataaat attataattt tatggatgtg
      901 agtcttaatg tagtttttat tctcctttat ttgagttttt gatgtcgtaa aatgtaaaat
      961 aatgataaat tatataataa gtatatagag gttaaaaaat agaatctagg gaatgataat
     1021 taattaaaag atattaatta aacagaggat ttatttatat ataataattt tggaggtttt
     1081 tatgaaaaaa acgataatgt ctttacaaca tctattagcc atgtttggag cgacagtatt
     1141 agttcccatt ttgacaggtt ttaatccgtc agttgcaatt ttctgtgctg gtgttggtac
     1201 attgatattt catttttgta cagaaggaaa agtacctgcc tttttaggtt caagttttgc
     1261 gtttatacca gttatactag cagctaaaga ggcatatggt ggagatttag catatgctca
     1321 aggtggtata atagtagcag gattaattta tattataatg tcgattatag taaaaatagt
     1381 tggtgtaaat aaaattaaat tatattttcc tgcacaagtt acaggagcta tgatagtagt
     1441 tataggatta aatttattgc caacagcttt tagtatggct tcagccaatt ttgtaatagc
     1501 atctataact ttagcaatag caattttaac caataagttt ggtagaggat ttataaaaca
     1561 attaggaata ttaatagcag ttttttctgg gtatataatc tgtttgatat taagattagt
     1621 agatataact actattacag aagcaagttt atttgcaata cctaacttta cagttcctaa
     1681 gttcagttta ggagcaattg tgattatatc tccagttgta ttagctgtat ttatggaaca
     1741 tataggagat atgactacta atggtgctgt agtaggtaaa aactttatag aaaatcccgg
     1801 attaaataga acattacttg gggatggatt tgcgactata gttgcagggt gtttaggagg
     1861 accagcaaat acaacttatg gagaaaatac agcagtactt gctataacta aaaactatga
     1921 cccttcaata cttagacgta cagcaatatt tgctatattg cttgcatgtg taggaaagtt
     1981 tggtggattt cttcaaagta taccaggttc agttatgggt ggaattagta taatgctatt
     2041 ttcgatgata acttatgtag gattaaaaac tataagggac agttcttgtg tagaaagtaa
     2101 aataaatata ttaatcatag cagttatatt attaataggt cttggaacca catatttatc
     2161 taataaaggt atttctattg gaatccctat aacaagtaca gtaaagataa ctggtcttag
     2221 tttagctgca attgttggaa ttgtattaaa cagaatttta aataatcagg actttaaagt
     2281 tgaagaagaa taaatttaaa gaataagttg tatattgaat aactaaaatt agttaatttt
     2341 ctatagacat ttgtaattaa tgttgatata atgattaaaa ataaatgaaa gaaagggcaa
     2401 ggtaactagg acaatgagaa tataatctat tttttataat ttaaagtatt gtaatttttg
     2461 aaaagcctat tttggtggct ttatttgcaa tgcttaaatt aaggagagta gattatagtc
     2521 tatacgttta tttgttatgc ctatttatag aatctctcct tatatttaag tgtgttaagg
     2581 agggattttt tatgttgtta gtaaaagtag agaatttaaa gaaatattat gcagataaat
     2641 taattttgga tatagataaa cttgaaatat tagaaaatga caaaataggt ctagttggtt
     2701 caaatggtca aggaaaaaca acattattaa aagcaatatt gggagaaata gaaattgatg
     2761 aaggatatac ttaccttaca gaaagctatt cttatataag tcagagtgaa aataatattg
     2821 aaacatgtag tcatagtaag gagaagagtc ttttaaatgc tccagataaa tttgaagaac
     2881 acttatcagg aggggaaaag gttaagttaa aaatagcaga tgcgctgagt aataagaaaa
     2941 atatcataat agctgatgag ccaacttcaa acttagataa aaaaagcatt ggggttttgg
     3001 aagatatgtt taaaaggcat gagggagcat tattattaat atctcatgat agacgttttc
     3061 tggatgagtt atgtacaact atattagaac tagaagatgg aaaactaaaa gcttacaaag
     3121 gcaattacac tgattattta atgcaaaaag atgaagaagt aaaaagagct gattttgagt
     3181 atcaagaata tgttaaagag aaaaaaaggc ttgaaaaagc tcttttatat aaaaaagctt
     3241 taagtgatgg cataagaaaa acaccaaaaa gaatgggtaa ttcagaagct aggttgcaca
     3301 aaatgggtgg tcagactaat aagaaaaagt tggactcaaa tgtgaaggct ataaaaagca
     3361 gaattgataa acttgaggta aagaataaac ctaaagtttc taaagaaatg aacattaaga
     3421 ttcaagatgg tatggagata attagtaaaa atctagtaga ggtaaaagat atgactctaa
     3481 agttagaaaa taagctcctg ttagataatg tttcctttaa gataaaaaga ggtaaaaaga
     3541 tagcattatt aggtgataat gggtgtggaa aaagtactct gataaaagaa atattggctg
     3601 ataaaaatga caatataaaa ataaataaca aggtaaaagt aggttatttt gaccaaaatc
     3661 aaagtttatt agatgaggaa aagagtgttc tatacaatac taaagttaat agttcatttg
     3721 atgaatcttt tataaggata aacttaagcc tatttgggtt taaaggtgat gatgtctaca
     3781 aaaaagtaaa agtacttagt ggtggagaaa aggtaaaaat agcactatgt aaaataatat
     3841 tggaagataa taatttttta gtatttgatg aaccaacaaa ttacttagat ataaaatcta
     3901 tggaagcact ggaaaaggca ctgataaata ctgataaaac tatgcttata gtgtctcatg
     3961 atagagtatt tgtatcacat atttgtaact atattataga gataaaagat gctaaaataa
     4021 gggagtttga ttgtaattat gacgaatata caattagcag aaataaaaaa actcctagta
     4081 gagaaaacca aatcaaaaaa gaaaatcttc tagtattaga aaatagactt acaactgtta
     4141 tatctatgtt atctatagaa aaagataatc taaaaaaaga attgtatgaa tcagaatata
     4201 atgaattact aaaacaaatc aataaattaa aaaatagctt ttagtgttaa ctttttaatt
     4261 acatctatat aagaagactg aaaatatttg ttgggaatat aagtatagtt attaaaacag
     4321 aaaagtattt tgttagaaaa ttaaaagtaa gctaattaga aagtggcctt attattgtac
     4381 tttataagaa ggccactatt tttatttaga atgataatgt gtagttgtct aacatttatt
     4441 ttgtatttag tgcagaattt attcagattt aaccttaagc ttggctactg tttcttcttc
     4501 aggagtaaca taaatagtac tgttagtttc ataaataacc atacctggtt tagaaccact
     4561 aggttttttc acattttttc tcttagtata gtctacaggc acctgagaag aaagttttga
     4621 cttactaaag aatgctgcta gcatagctcc ttcaaataca gtattatcag ggacttcctt
     4681 accagcacac tttattatta catgagaacc aggaatattc tttgtatgca tccataagtc
     4741 atcattatca gcaagtctta gtgtaagata gtcattttgc ttattgtttt taccaaccaa
     4801 tattttaaat ccatcagaag aaacaaattc atgaggtttt gtagatggga tagtatcctt
     4861 tttactgttt ttcttttgag tcttgatgta tccaacctta gcaagttctt cttttatatc
     4921 ttgtaattca gctaaatttt cacagttttc aatacttaaa attatgtttt ctaagtaatc
     4981 tatttcttcc ttatttaagg aaatttgatg agatatctcg actttagcat gtttcatttt
     5041 gttatacttt ttaaagtatt tttgagcatt ttcagatggt gtcaagtttt tatttaattc
     5101 tattgttaca tcattacaat tttcatcata gaagttagca acttcaatac tttccatacc
     5161 tttttctacc atataaatat atgaagtaat caattctcct tttatcttat aaatgtctgc
     5221 attttcggat tctgataatt cttcttcttg ttttttaagt ttattataaa gtctatcaag
     5281 cttaacagat atactcttct ttaaatcaga tgaacgttga ttaattctat ctttaatatc
     5341 cttagttcta tagaaatctt ccagaatacg agacatacta tccttattta tatatgataa
     5401 atcgctaaat aatgtaaggt ttatacaact gaaatcaact accttatcca cctttttatc
     5461 tataataatg caaggagagt atttgttaga atttatatca ttgaataaat tacaaaatac
     5521 tttgtgtaaa gaatcaaatt gttcatcaga tatatccttt atgatagcat tttgatttac
     5581 acctgctctg tagcaaattt ctttagctat aatagggctt atacctagaa atttagaata
     5641 tatagactta aagataggtc cttccaattc ctctaggttt ttaataaaca aatccttaga
     5701 tatatcatca agagggttga gtttgttttg ttctggtggc aatgaataat catgaccagg
     5761 taaaacttga cgaactctac ttatgctaaa agggactctt tttatagaat ctataatttt
     5821 attttcttca ccatgagtta ttattatgtt gctatgtctt cccataattt caatcataat
     5881 atttttaact gtcttttctt ttaattcatc taaagattca acacttattt ttattattct
     5941 ttcaaaacct atttgagaaa tttctactat atttccacct tgtatgtatt ttctaagtaa
     6001 catacaaaac ataggcgctt ttagagggtt ttctttttga taattacttg taagataaac
     6061 tctaggattt gaggcacttg cacttaaaac caatctaaaa ttttctttat tatttcttat
     6121 attaaaaatt acctcatcat cttcaggttg atgtatctta tctatttttc cacctgtaag
     6181 ttttgatgat aattcatcga ctattgaatg tataactaat ccatctaatg ccatttatag
     6241 cacccctttc tttgaccaaa atgagtcagt aaattaatta tacacataat atacgctttg
     6301 tgactagggg gaatttaaac aatagagatt aatatttaaa ttgtataatt atttatattt
     6361 attagagagg aaactttatt tttaaaatta ataatttaaa gtagattaaa tataaagtaa
     6421 atatagtata attattgtgt agagtataag ctatgaaagt atatgaactt tacagaaaaa
     6481 atcaatttta aggttctata gtatataaat atgaaagaag gttgaaaaaa tgagatttat
     6541 cgatttaaga agtgatactg ttactatgcc tactgacgaa atgagagaag ctatggcaaa
     6601 ggctcctgtt ggagattcaa tctttagaga tgaccctact gtaaataaac ttgaagaatt
     6661 agcagcagct aaagttggaa aagaagatgc tattttcctt ccaagtggaa cttttgggaa
     6721 tcaattagct ctatttactc attgcctaag agggcaagaa ataattattg gtaaaggtta
     6781 tcacattgtg actcatgagg ttggggcacc tgctgtaata gctggagttc agcttagaac
     6841 tatagatgaa gacgaaagtg gagctctaaa tcctgaactt gttgaaaagg caattagaag
     6901 agatgacata catgaaccac agacagggct tatatgtgta gaaaatgcat attcaggtgg
     6961 aacagttgtg agtcttgata atttaagaga aattaaaaaa atagctgaga aacataactt
     7021 accagtacat ttagatggag caagattatt taacgcagca ttaactttgg gtgtagaagc
     7081 taaagaaata gcaaagtgtt gtgatagtgt tatgttctgt gtgtcaaaag gtttagctgc
     7141 accaatgggt tctatacttg ctggaaataa agaatttata gcaaaagcta gaagaaagca
     7201 aaaagttatg ggtggaggaa tgagacaagt aggtatagtt gcagcagctg gtataattgc
     7261 cattgaaaaa atgactttaa gattgaatga agaccatgaa aatgcaaaat atttagcttg
     7321 tgaattaaat aaaattgatg gcattgaagt aaacaatgtt aatccagata taagtatggt
     7381 attttttaag atgagtgaag atattataaa agaggatgtt ttaataaaag aattttttga
     7441 aagaaatata aaaattaata aaatggaaaa tggtgaatat agatttgtaa ctcatgtaga
     7501 tattactaag gaagatttag actatgtttt aaaaacactt aaagaattaa taggtgtatg
     7561 ttaatagata tctactagaa ggattatagc tagttaccag atgtttaatt aaaaaattca
     7621 tagacagttt aaataaaaca tacataaaat tcatatagaa atattaatat ataaacatag
     7681 aaagaactag cttaaaaaca taatataatt accctaattg taatggcaac tctccctcac
     7741 atcctcaaat tatagttgtc attacaaaac ttttcccata aattataagt ttatgggaat
     7801 ttttttatgt tataatagtt taagtgttaa tttacgaagg agcgatactt atgaaatttt
     7861 ggaaactaca tggaatagga aatgatttta tagcaataga tggaagattc gaccagataa
     7921 atccatctga ttatactgct ttagcaaaaa aagtatgcca tagaagattt tctgtaggag
     7981 cggatggatt gttagttgtg aaagattcaa aagttgcaga tgtagaaatg gtatattata
     8041 attctgatgg ttcaagagca gctatgtgtg gaaatggcct tagatgtttt tgtaaatttg
     8101 tttatgataa ttgtatagtt aaaaaagaaa gttttacagt agatacatta gatggtataa
     8161 aagatataaa agtaaatctt actaatagag aaataaactc tataagagtc aatatgggaa
     8221 aaggaagttt tatagctaag gacgttcctg tacttacaaa taaagaacgt tttgtgcaag
     8281 aaagtataaa ggttttagat agggagctta aagttacttc tatgttgatg ggggttcctc
     8341 atacagtagt tatagtagat gaattagatg tagatgatgt ttgtaaatat ggaaaagaga
     8401 ttgaaaataa taaaatattt cctgaaaaaa cgaatgtaaa ttttgtaaag gtagaagata
     8461 agtataatat acatgtttat acttgggaaa gaggttgtgg atatacttta ggttgtggta
     8521 ctggtatgac tgcatcagca atagtgtgca atttacttaa tatggtagaa agtagtgtaa
     8581 atgtaacgtc tcaaggtgga acagttaaaa tagatgtagg agatttctct tatatgacag
     8641 gtccagcagt aaaaatatgt gaaggtattt tggaggttta attaatggct ataagtatga
     8701 ctggttttgg aagaggagaa tacaaggatg ataattatta ctttttagta gagtgtaaaa
     8761 cgataaatca taagtattca gatataaaca tacgtcttcc aagaaaaatt tcatttttag
     8821 aggataaagt tagaaattta gtaaaaaatt atgtaaaaag aggaagagta gatttataca
     8881 taaagtttga cttattaggc aaagaagatg taaacttaaa ttttgatgag ggattagcat
     8941 ctcagtatat agacatacta aaagaaataa aaaataaatt tgatattata gatgatatta
     9001 gcgttatgaa tgttgcaaag tttcctgata ttgtgaaaat agaagaaaag gaagaagatg
     9061 aagatttatt gtggtcaatg ttgaatcaag cagttgaaga tgcattaatc aaattaagag
     9121 aaatgagaag tgaagaaggt aaaaaattag ctgaagatat tgccatgaga tgtgatttat
     9181 taaaaaatca tatagaagag attgaaaaat attcaagtag tgttgtagaa gattatagag
     9241 aaaaattgaa tttgagaata agtgaattac tggatgaccc aagtataata gatgagaata
     9301 gattagcaca agaagttgca atatatgcag ataaaagcag tataacagaa gaaatagtta
     9361 gatttaaaag tcatataggg caacttaaaa atactatatt taaagacgac tctataggta
     9421 gaaaaataga tttcttaata caagagatga atagagaaac taacactata ggttcgaagt
     9481 catctgatat aaatataact aatttagtag tagaagtaaa aagcgaattg gaaaaaataa
     9541 gagaacaaat acaaaatata gagtaagaat acaatattag aaggggaatg cttaaatgtt
     9601 tgtgaaaaaa ggattattgc tagttgtatc aggaccatca ggtgcaggaa aaggtactat
     9661 ttgcaaagaa ctacttaaag aaaatgatac aataaaactt tctgtatcag ctactacaag
     9721 aaaacccaga actggagaag ttgatggagt aaattatttc ttcataagta aggaaaagtt
     9781 tgaagagatg atagaaaaag gtgagttttt ggagtatgct caaatttatg ataattttta
     9841 tggaactcca aaagcggcaa taatggaatg tttagaaaaa ggacaagatg tattactgga
     9901 gattgaaatg caaggagcaa aacaaataaa agaagtttgc ccagagggag tatttatatt
     9961 tgtactacca ccatcactta aagaattaaa aaatagaatt gttggaagag gtacagaaac
    10021 agaagctgaa atagagaaga gatttagctg tgcatatgaa gaaattaaaa tgattaagga
    10081 ttatgattat tttatattta atgaagatgt aaaaacatct gctaaagaaa tagaaggtat
    10141 aatatcatct gaaaagaata aagttagcag atataaaaat attataatag agaaatttaa
    10201 ggaggaatta taattatgtt aaaaccatct atcaatgagg tactagaaaa aatagacaac
    10261 agatactatt tagtagggac tgtttcaaag agagcaagaa aattaattga tggagaagaa
    10321 ccatatgttt caaataaaac taaggaaaag cctgtatgtg tagcaactaa agaagttgca
    10381 agtggaaaaa taacatatag attattgaca gaagaggaaa tagagataga agaagctaga
    10441 catcatgctg agcaacacca acaaatttca gaagaggagt aaggtcatgc taaaagataa
    10501 aactgttgta attggcataa gtggcggtat agctgcatat aaggcttgtg atgttgtaag
    10561 taagttaaaa aaactaaatg caaatatcca tgttataatg acaaaatcag caacagaatt
    10621 tgttaaacca cttacatttc aatcgctgag tcaaaattat gtagtagaag atatgtttga
    10681 agaaccaaaa acttgggaag ttgaacatat atcattagca aaaaaagcag atttattctt
    10741 aatagtgcca gcaagtgcaa atgttatagg caagattgca aatggtatag ctgacgatat
    10801 gttgacaact actgttatgg caacaaaagc acaggttctt atagcaccag ctatgaatac
    10861 taatatgtat gaaaatccaa ttgttcaaaa aaatatacaa actttaaaga gctttggata
    10921 taaatttatt gaaccggaaa gtggaaggct tgcatgtgga gatattggaa caggtaaact
    10981 agctaatcca gatataatag tagaggaagt tttgactaat cttactaaag agcaagattt
    11041 aaaaggtcaa agtatgatag ttacagctgg tccaactgta gagagtatag acccagtaag
    11101 atatttaact aataggtctt ctggtaaaat gggatattct atagcaagag aagctatagc
    11161 tagaggtgct gatgtaacat taatatcagg tcctacaaat ctttctattc cacaaaatct
    11221 taaaaaattt gttcaaatag agtcagcaca agatttgtat gaagcagtag tatcaaattt
    11281 aagtgaaaat aaaatagtaa ttcaaagtgc agcagttgca gattataaac caaaaactta
    11341 ttctgacaaa aaaattaaaa agaagaatga tgatttatca atagaactaa gtagaaatta
    11401 tgatattgct tatgaaatag gaaaaataaa agaagataag atactaattg gatttgcagc
    11461 tgaaactaat gaccttatag aacatgccaa aggaaaaata aaaaagaaaa atttagattt
    11521 tattgtggca aatgatttaa ctaaagaagg tgctggtttt agagctgata ctaatattgt
    11581 aaaaataata gatgtagagg gaaatattac tgagtatcct aagatgaaaa aagaagaagt
    11641 agccaatgtt attttagata aagttaaagc gttgcttgag aaataagacc ttttttaaat
    11701 atgatatttg tgtattttat cacagctaaa gtggctgaaa gctgcaattt aattttagcg
    11761 agtaaaaact cgcaaatgtc agttaaattg tagttttcag catttatttt gtcataaagt
    11821 ataaaatata attaatagtt aattattaaa ataaagttaa tattaataac ttgaaattgc
    11881 ttataaattc tgagatttta atatcttgta aagtatatta aaatatgaac aatatattaa
    11941 atttaagtag aggttttata atgaaaaaat atgcaaaggt aatagttaga agtaatacta
    12001 tatatacaga taatttattt acatatcaaa ttcctgtatt tttatctgat gtaataaaaa
    12061 ttgggcacag aatattagta ccatttggaa aaggtaataa accaacagaa gcctttgtat
    12121 ttcaatttac agatagctta gatgaaaaaa taaaaataaa agaaattatt gatatattag
    12181 atgaaaatcc gatatttaga aaagaagatt tagagttggt ttattggatg aaaaatagat
    12241 atttgtgtac ttatatagaa tgtataaatt tgatatatcc aaagggatac aaattaaata
    12301 attataaagt agtcctatta ggtgaaagtt taagtggatt aaatgatatt gaattgaagg
    12361 aaaaaatatc aactttaagt gataaaaata gagaaatagt agagaaagtg attgatagta
    12421 aaggtaaaat taaggttgat aagttaaaat atataccaaa cttaaatagt tctttgtaca
    12481 caatgaataa gaatggaatt ataaaattat gttgggaata taaaaatcac aaaaatgaaa
    12541 agaaggtatg ttatatatct ttgagtttag aaagtgataa gattgacgat tatatagagc
    12601 aaaataaaat aaatgtggga agtaaacaaa aagagatatt aagttttctt aaaaataatg
    12661 aaaatgtaga gataaatgat ttattggatt tattaaatgc ttcaaaacaa agtataaatt
    12721 ctctaagtaa gaaaaagcta ataaccctag aatttaagga ttattataga gagccaaaaa
    12781 gtatttacaa atccgtacta aaaagtataa aattaaacaa tgagcaacaa gaagcagttg
    12841 atgagataaa gtcgaatatg tttgtagatg ataaaaaacc atacttaatt catggagtaa
    12901 ctggaagtgg aaaaactgaa gtttacatgg aaataataga atttgctcta aatcaaggct
    12961 tagacagtat attcttagta cctgagatag cattaactcc tcaaacaata gataggctaa
    13021 agagtaggtt tggagatttg gttggagtgt tccacagtaa actatctgaa ggagaaaaac
    13081 atgatgttta caaagctgtc aaagcaggta aagtaagagt gttaattgga gctaggtcag
    13141 ctttatttgc accttttaat tccttaggct taataataat tgatgaatgt catgagtcat
    13201 catataagtc tgagaagaat ccaaaattta atgctataga agttgctaga tttatggcat
    13261 taaaaaataa tataactctt attttaggtt cagcaacgcc ctcaattgaa gagtattata
    13321 gggcaaaatc tggagaatac aaacttataa atataaaaag tagagcaaat gataagcctc
    13381 ttccaaacat tgaagtggta gacatgaaag atgagttaga taaaggaaat agaagtatat
    13441 ttagtttgaa attacaaaaa gaaatacgtt atgcgattga agaaaataat caagtaatac
    13501 tatttttaaa cagaagaggt tatgcaaatt ttgtatcttg tagaaagtgt ggatatgtgt
    13561 ttcaatgtga aaattgtgat atatctttaa cttatcataa gaaaagcaat actggaagat
    13621 gccactattg tggatatgag aaagaaattc caaaagagtg tcctgaatgt aaaagtactt
    13681 atgttaagcc atttggagtt ggaactcaaa aaattgaaga ggaattaaaa tatatttttc
    13741 cagatataaa aactttgaga atggataaag atacaacttc aaaaaaaggt gctttagatg
    13801 agatactaaa taaatttaaa gataaagaag cagatgtact tattggaaca cagatgttaa
    13861 gtaaagggct ggattttgag aatgtaactt tagtaggtat tttgtctgca gacatgatat
    13921 taaattttcc agactttaaa agttttgaaa ctacatttca attgataact caagtctctg
    13981 gaagagcagg gagagctgat aaagagggaa aagtagtact tcagacttat gacactgaac
    14041 actatgctat taagcatgct attgaatatg attatgaggg tttttatgaa gatgagataa
    14101 aaataagaaa agcatttgga tattctcctt ttaataatat gttaagtgta gttgttagtg
    14161 gtgaagatga aagactagtg ataaaaaata taaaaaatat gcatgcatca ttgatttatt
    14221 tattagaaaa aaggggtata aatgatttag gatttatatt aggtccaaat ccatgttcaa
    14281 tatcaaaaat aaatcaaaat tatagatggc aaatactctt taaagatgaa aatattgaaa
    14341 ttaatctctt aaagggtata ataaaatata tatgtataac aaaacgagat ttgatatttg
    14401 ataagaatat caatgtatct atagatatta atccaaacag tgtattataa atttaggagg
    14461 aattataatg gctttaagac aaatagttca aataggagaa ccagtattaa gaaaaaaatc
    14521 aaaaaaggtt gaaaaaattg atgaaaagat aatacaatta ttagatgata tggcagaaac
    14581 tatgtatgat gcagatggtg ttggactggc tgcacctcaa gttggaatat taaaaagagt
    14641 agtagtaata gatattggag aagagcttat agaacttata aatcctgaaa taatagaaac
    14701 atctggggag caaatagatg aggaaggatg tttaagtgtt gttggagaag cgggaaatgt
    14761 tagaagacca aattatgtaa aggtcagagc tttaaataga aatggtgaaa caatagagtt
    14821 agagggagaa gaacttttag ctagagcatt ttgtcatgag atagaccact tagatggaat
    14881 tttgtttgtt gacaaaatag aaaagtagta ggagttgatt tgatgaaaat agtatttatg
    14941 ggaactcctg atatagcagt tccatgttta caaaaaataa tagatgagaa gtatgaaata
    15001 ttgggtgttg taactcaacc agataaacca aaaggaagag gtaaaaaact aggtatgagt
    15061 ccagtaaaag aactggcaat tgaaaataat atacctgtat atcaaccagt aaaggctaga
    15121 gataaagaat ttatagataa aattaaatct ttaaatccag atgtaatagt agttgtagct
    15181 tttggacaga tacttccaaa agaaatatta gagattccta aacttggatg tataaatgtt
    15241 catgtttctt tacttccaaa atatagaggt gcggcaccta taaattgggt aataataaat
    15301 ggtgaagaaa agactggtgt tacaactatg tatatggatg aagggctaga tactggagat
    15361 atgatactaa agacagaagt aaatcttgat gaaaatataa cagcaggaga acttcatgat
    15421 aaaatgatga atataggcgc agaaacttta aaagaaacat taagattaat tgaagaagga
    15481 aatgctccaa gagaagtaca aaatcatgaa gaattttcct atgcgccaat aatgaataaa
    15541 tcattaggta acatagattt ttcaaaaagt gccagagaaa tacacaattt agttagagga
    15601 gtaaatccat ggccaagtgc ctatactacc tataatgatg tcataatgaa agtttggaaa
    15661 actaaagtgt tagatgaaaa aagcacaaaa gatgtaggta caataattga tgtaagcaaa
    15721 gatgggataa aagtaagtac tatagataat gtacttttaa ttgaagaaat tcagatgccg
    15781 aataaaaaga gaatgttggt tggtgaatat ataaaaggga atactataga aactggttta
    15841 gtattgggtt aggtgaaaag tatgacagat ataaagaagt atttaacaag tgttgggatt
    15901 ttgattttaa tattaggaat tttgatagga gttgttaatt tttttataat aagtttaact
    15961 caaatattct ccttgatgat aaatattata ataatatcac taatacttat aatactatgt
    16021 tcaacagcag ttacttatag agtaattaaa ggaaagtatg ttaactcaaa tataatgaaa
    16081 ataaatttta atattgtcag tggattattt cctattatat ctttcattgc atcatcattt
    16141 ggtatgtcaa aaagtgatat tagaagaata tatataaagt taaataatga atatatatac
    16201 agtaataaat ataattttaa tccagaggat ataataattt taatacctca ttgtattcaa
    16261 gagaatagtt gtaaattaaa agttactaat gatatagata attgtaaaga atgtggaaga
    16321 tgcaacatag gagaattaat taagctaaag gaaaaaacta atgtaaaaat atttgtagct
    16381 actggaggaa ccctagctag aaaaattata atggataata aacctaaagc tgttgtagct
    16441 gttgcatgtg aaagagattt gacatctgga atacaagata ttaagaaaat tcctgtttta
    16501 ggtgtattta acaaaagacc taatggacct tgtgtaaata ctaatgtaga cattatggat
    16561 attgaaaaag ctataggctt tttaacagga aaaaatatat tagtttgtaa ttaaactgtt
    16621 tttaagtgaa gtgaatatta agaggatgta taataaaaat atattttagg agagtgttat
    16681 ttatgtaccc tgtatatggc ggtttttggg gatttgaccc aacaatggtt gtattaattc
    16741 cagctatatt acttactata tatgcacaat ttaaagtgag ttcaacaaca aataagtatt
    16801 taagagtaaa tacacgtcga ggatatactg gagagcaaac agcaagaaga gtacttgatt
    16861 caaatggttt gtatgatgta aagatagaaa tggttagagg gcatctaagt gaccattatg
    16921 acccaagaag aaaggctgta aggttgtcag aagatgtata ttatggaaca tctataactt
    16981 ctgttgcagt agctgcacat gagtgtggtc atgccataca acatgctaaa ggttatgcac
    17041 ctcttcaaat aagaagtagt ttagtaccag tagtgaattt tgcttcaagt atatcttggt
    17101 ttttaatatt tttaggattt attatggctg gtccattttt aaaaattggt atactattgt
    17161 tttcggcttc agtgttattc caaataataa cattgcctgt agaatttaat gcttcaagta
    17221 gagcaatcgt tcaacttggg aatttaggga ttatagatga aagtgagtca agacaaagta
    17281 gaagagtact ttcagcagca gctttaacat atgttgcagc agcattggtt tcaatacttc
    17341 aattacttag attgttacta atagctcaaa gaagaaatga ctaaaagtaa agtgggttgt
    17401 ttagaaacaa ccctttttta tgtttaataa aagggagaaa tttatatgga tgcaagagaa
    17461 gttggattta aagtattatg tgatatagaa aaaaatgaca attattcaaa tattgcaata
    17521 aataagcatt ttaaaaattt agaaataagt gatatggata gaggacttgc aacagagtta
    17581 atttatggag taatagaaaa taaatattat ttagattata taatcaataa actttcaaaa
    17641 ataaaggtaa aaaaaatgtc aacttatgtt aaaatctttt taagaatggg aacatatcag
    17701 attttatttt tagatagtat atcagattat gcagcagtta atgaaactgt aaaattatct
    17761 aagaaatatg ataaaaaatc ttctggtttc ataaatgcta ttcttagaaa tgaaataaga
    17821 gctaaagaga ctataatgga cataactgag gaagatagtg taaaatactt atctataaag
    17881 tattcctata actcttggat tataaaaaac tggatagata aatttggaca agaatttgct
    17941 gaagatttgt tggaagcaaa taatgaaaag cctagtatct atataagaac gaatacactt
    18001 aaaataagta gagaagaact tattgaaaaa ttaagtgaaa tgggtattgt atgtttaaaa
    18061 gttcctatgg tagaagaagc tattaaagtc gaaaaaatga aaaatataga aaaaaatgaa
    18121 ttatttaagg ctggtttatt tacaattcaa gatataagtt ctatgatagt agggaaagta
    18181 attaatccaa aagaaggttc atttgttttg gatgtatgta gtgctcctgg agggaaatct
    18241 actcacttag ctactttaat gaacaatact ggtcaagtag tagctagaga tatttttgag
    18301 cataaactaa agcttataaa ctctactgta aatagattgg ggcttaaaaa tgtgtttgta
    18361 gaaagatttg atgcttctga gattgatgaa aatagtataa gtaaatttga ttatgtttta
    18421 gcagatgttc cttgctctgg ttttggtata ataagacgta aaccagaaat taagtataag
    18481 aaagaagaag agttaaaaga catcacttct atacaaaaga aaattttaga aaatgcatct
    18541 aaatatgtca aagttggtgg aactttagta tatagtacat gtacaattca agatgtggag
    18601 aatataaata tagttacttc ttttgttgaa gaaaatcaca actttgaatt tgttccaatt
    18661 gatacagtaa atgtagactt agacaatcaa gataaaggat atttaaagat atatcctaat
    18721 attcatggta tagatggttt tttcatagca aaattaaaga gaataaggta gtgagagaat
    18781 ggaaaagaaa aagatagtat taaaaaattt tactgaagat gaacttaaag agtttatgaa
    18841 aactatagat gaaaagccct ttagaggaag tcaaatattc tcttggatat ataagggtgc
    18901 aaaaactttt gatgatatga acaatatacc aaaaagtttg agaaataaat tagaagaggt
    18961 ttcatgtata gggcatatag atatagaatt aaagttagaa tctaaggtag ataatacaaa
    19021 aaaatatttg tttttattag atgatggaaa tataatagaa actgtgatga tggattatga
    19081 tagtagagtt actgtctgtg tttctaacca agtaggttgt aggatgggat gtaatttttg
    19141 tgcatctaca atggatggat taattagaaa cttagagcca tgggaaattt tagaccaagt
    19201 tattaaaatt caagaagata ctggtaagag ggtatcaaat cttgtattga tggggagtgg
    19261 tgagccactt gataactttg aaaatacaaa acaattttta aaaataatta acgaaaaaaa
    19321 tggtcttaat atagggtata gacatataac tctttcaact tgtggaatag tacctaaaat
    19381 gtatgagttg gcagacttag aaatagctat aaatttagct ttatcacttc attcaccata
    19441 tgatgaagaa cgaagaaaaa ttatgcctgt agcaaatgct tattctattg aagaaatatt
    19501 gaatgcatgt agatattata taaaaaagac aaatagaagg gttacatttg aatattctct
    19561 tataaaagga gtaaatgact cagaaaaaga agcaaaggca ttagctaagc tcctaaaagg
    19621 tatgctatgt catgtaaatt taattccaat aaataaagtt gaagaaagag aatacgaaaa
    19681 accagataaa gcatttattt ataaatttag ggatagtttg gagaagaaca atatacctgc
    19741 cacagttagg atgtctatgg gttctgatat tagtggagct tgtgggcaat tgagaagaaa
    19801 atacaagtaa tttgtaagga ggaagtcgta tggtttatag ttgtgcctcc catataggaa
    19861 aaataagaaa aaacaatgaa gactattgtg agggagaagt tatagataca gaacatggtc
    19921 caataggaat atttgccata gctgatggaa tgggtggaca taaaaaaggt gaagtcgcca
    19981 gtaaattagc agtagaaaat ataattgatt ttctaaagga aaacttatta caacatgata
    20041 atgtaaaaat agactatata gatgatatat taaaacaggc ttataataat gtaaactcaa
    20101 ttgtgcacaa aaaatctatg gaagatatag aatttgaagg aatgggaact acattagtta
    20161 cggctatagt gtataataat gtcttatatg tggcaaatgt tggagatagc agatgttatt
    20221 tgttaacaga tgaaaaattt gataaaataa ctatagacca ttccgtggtt gaagaactta
    20281 tgatggccca tgtcattaca gaagaagagg caagaagaca tccacagagg aatagaataa
    20341 ctagagcaat tggaacagat gatatggttg ttgtagatat ttttaagaaa gaaatcaaaa
    20401 aaagtgatat aatacttctt gcgacagatg gattaactgg gtttattgat gatgaagata
    20461 taagagattt aatattagat tatgaatatg agagaactag taatataagt gaagaattga
    20521 taagtatggc caatgatgtt tctggtaaag ataatgtttc ggttatagtg ataaaagtat
    20581 aattaggacg gtgatattgt gggagataca attttaggaa atcgatatga aatcatcagg
    20641 aagattggtg atggaggaat ggcctttgta tatgaggcta aagacagatt attaaacagg
    20701 actgttgcac ttaaagtact tagacctgaa tttgtagatg atgatgaatt tctaacaaag
    20761 tttaaaagag aggcagaagc agtagcaagt ctttcacatc caaatatagt aaatgtttat
    20821 gatgttggtg aagatggaaa agttcactac attgtaatgg agtttgtaga tgggaagaat
    20881 ctaaaagaga ttatacaaga tgaaggtata ttagatgaat atactgcatt agatataaca
    20941 aaacaaatag ctatggcact tagtgcagcg cacaaaaagg ggattataca tagagatata
    21001 aaacctcata atattctcat atcaaatgaa ggaagagtag taaaagtggc tgattttggt
    21061 atagccaaag ctgtttcaaa ttcaacaatg actaatattg gtagtataat aggttcagtg
    21121 cattattttt caccagagca agctaaaggt aaatttgtaa ctaataatgc tgacctgtat
    21181 tctctaggta tagttttata tgaaatgttg ataggaaaag ttccatttag gggagatagt
    21241 ccaatttcta tagcacttca acacattaat gatgatatag actttacatc agaagaaaaa
    21301 gttaggattc ctcaaagtgt aagaactaca ataaaaaagc ttacagaaaa atctagtgca
    21361 gatagatatc aaactgctga agaattgata gaagatatag agtatataga aaaaaatatt
    21421 gatttagatt ttataaaaga atatgatgat tttgcaacta agaaaattga tgaaaaagaa
    21481 attaataaag ttgtaaatcc aacacttgca aaaccagctc ctgaaaaagt ggttaagcct
    21541 gttgaagtag ctgatttgga tgatgatgaa gattactatg atgattttta tgaagaagat
    21601 gatgatgaag atgaagaaga ggaagagata atgagagcta aaaagaatca gagacctaag
    21661 agtactccaa gtaagagaac taagaaaaag aagaaaaaac aggaaagccc aaaatctaga
    21721 agaagattaa aagtaattgc ggctgttttg atactgatat tgtgtgctca agtattctta
    21781 gcatataagt ttttatttgc tggagggttt ggcaataaat ctttgactgt tcctaatctt
    21841 gtaaatatga cattagaaga agctcaaagt gctgttgaaa aagaaggatt atacctgagt
    21901 gtaaaaagtg aagagtataa tagtgaagtt gatgaaaatt gtataatatc acagacacct
    21961 gaaggtggaa gtacaaatgt caaaaagggt gatactataa atgttgtcgt aagtaaaggt
    22021 tcaagtcagg catctgttcc taatgtagtg ggacttactt tgagtaatgc aaaacaactt
    22081 attgaagaaa ataacttaaa agtgggaact gttaagtatg aatacagctc aatatataaa
    22141 gaaggtacag ttttaagtca gagtccgggt gctggctcat caagagctca ggaaggtgat
    22201 gaggtaaacc tatatgtaag caaaggttca gaaaaatcaa atacacagac tccaacagta
    22261 ccagataaaa aaccaacaac accagagaat aatacaccaa cagaacctgg ttcaaactca
    22321 ggaaacagtg gtggaaattc aggaggctca aattcaggaa atagtggtgg aaactcaggc
    22381 aataatggaa gtaactcagg aggttcaaac tcaggaaata gtggtggaaa ctcaggaggc
    22441 tcaaactcag gagataatgg aggaagttca ggaggctcaa actcaggaga caatggagga
    22501 agttcaggag gttcaaactc aggagacaat ggagatagtt caggaggctc aaactcagga
    22561 gataatggag gaacttcatc aggaactggc gcaaacattg gtaaaacaga ataaatatta
    22621 ataaaataag agctgtcctt ttatagaaaa tattttcttt aaagggcagt ttgttttgta
    22681 taaaatactg aattggttat aatataagga gaaaagtatt tatgaagaag aaaacagttt
    22741 taattacagg aggagctaga gggattggta aagctatgtc taaagctttt gcaaaagaag
    22801 gttacaatgt attagtaaat tttaataagt cagaaaatga agctaaagag ttgtacacta
    22861 tattaaatga aaaaaatttt tctgtaaaac tttttaaggc tgatatttca aatagagaag
    22921 atgtagagga tatggtagat tattgtataa aagaatttgg aggattggat gtacttgtaa
    22981 acaatgctgg tgtaagtcaa gataagttgt ttacagatat aactgatgaa gattgggata
    23041 atatgatgaa tattaattta aaaggaagct tttattgttc acaagttgct ttaaaataca
    23101 tgatatcaga aaaaaaagga aatataatta atatatcttc aatctggggt atatcaggtg
    23161 cgtcttgtga agtgcattat tctataacaa aagcaggcat aataggtatg acaaaggcat
    23221 tagctaaaga agtaggacca tcaaatatta gagtaaatag catagctcca ggtgtcatta
    23281 atactgacat gttatctgga tataatgagg aagatataga cgctcttgtg gaagaaaccc
    23341 ctctaatgag gctaggaact ccagaagata tagcaaattg tgctattttc ttggcatcag
    23401 acaaatcaaa ttttatcact ggtcaggtaa ttagtccaaa cggaggattt gttatttaaa
    23461 aaaaatgtgg tattatataa aaataggaaa gaataacacg atatactact cataaacagt
    23521 atgtgtttat ataaatttta taaagggagg catttgatgc tagaaggaaa aattataaag
    23581 gggattagtg gattttatta tgtagatact tataatggta tttatgaatg taaggctaga
    23641 gggatattta gaaagcagaa aataacacct ttggttggtg atagagtcaa aataagcatt
    23701 gttgatgaaa atgaaaaaaa gggtatctta gaagaaatcg acagtagaga tacagaactt
    23761 ataagacctc ctattgcaaa tgtagataaa gcattaatag tattcgcaat aaaaaatcct
    23821 aaaccaaact tatctctttt agatagattt atagttttgg cagaaaaaga aaatttagaa
    23881 actgtaataa tccttacaaa agcagattta gatgataatg atacattaga aactgttaaa
    23941 aatatatatg aacttagtgg ctataaagtc attcctgtaa gcaatattac taagttaaat
    24001 atagataaag taaaagaaga attaaaagaa aatgtagtag tgtttgcagg accatctgga
    24061 gttggaaaat caagcttatt aaatgaaata gatgaaaatt ttaaacttca aacaggagtt
    24121 gtaagtgata aaataaaaag gggaaaacat actactcgtc acgctgaact tttaaaatta
    24181 gaatttggtg gaatggttgc agatacacca ggttttagtt cccttgccct tgaagatata
    24241 gaggaagttg aacttaaaga ttattttata gaatttgata aatttaatga ttgtaagttt
    24301 ggttcaaagt gtattcatga aaatgaacct aattgtgcta taaaagaagc tgttacaaat
    24361 ggagaaatat ctaaagaaag atatgatagt tatatacagc tgctacatga aataagacaa
    24421 aataatagta ggaggtatta gaaacatgat taaattagca ccatcaatat tatcagcaga
    24481 ttttgcaaaa ttattagaag atgtaagaaa agtagaaagt gcaggatgtg aatatcttca
    24541 tatcgatgta atggatggac actttgtacc aaacattaca ttaggaccac ttgtagtcaa
    24601 aagtttaaag aaagaaaata taaatatggt atttgatgct catcttatga tagaaaatcc
    24661 agaccagtat attgaagaat ttgtaaaagc aggatgtgat ataataactg ttcaccagga
    24721 ggcttgtgtt catctacata gaactataca aaatataaaa tcacatggaa taaaagctgg
    24781 tgtagtactt aatccagcta caccagtaga tacgattaaa catgtactac ctgatttaga
    24841 tatggtatta ttaatgtctg ttaaccctgg atttggagga caatcattta ttccttgtgt
    24901 tttagataag attaaagagt taaaagctat tatagatagt caaggattaa acattgatat
    24961 agaagttgat ggtggtataa gccctaaaaa cgtagccgaa gttgtacaag caggagctaa
    25021 tgtaatagta gcaggttctg caatatttgg aagtgatgac attcaagaaa cagttaattt
    25081 atttagaaag aatgcttctc ttgaagaatt agtttaaatt taataatgaa aatctgtatt
    25141 gttttaaatg gcgaaattga agattacgaa gttacaagag atattataat taaggaatgt
    25201 tatgactgca taatatgtgc agatggaggg gcaaatcaca cttataaaat ggaaataatg
    25261 ccagattata tattaggaga tttagattca gtagaagaag aaaagataaa cttctataaa
    25321 aataaaggtg ttaaatttga aaaatttcca tctaaaaaag atgagactga tacagagctt
    25381 tgtctttttt tagctaagac acttaaagca aatcatattg atttttttgg tgctttaggg
    25441 ggaaggattg accacactct tgcaaatata aagctattat attatttaaa agaagatggt
    25501 atatattcta ggatactttc tgataaagaa gagatgtata tagttgaaaa tgaggaaatt
    25561 tcattgtatg gaaacccagg ggacactatt tctgtaatag ctataaatgg tgatgctaag
    25621 ggtgtaacac ttactggctt agaataccct ctcgataatt attatatgaa atactctgta
    25681 cctattggaa tatcaaatgt tatgttgagt aattcttgta agattaaagt agagcaaggc
    25741 tgtgtacttg tagttagaaa tttataaaat ttgattttga caattggttt tatattgtag
    25801 agcagataca atcaagtaaa atatatttat gattgtatct gctttttagt atataattat
    25861 aaatatataa taaactttga cataaggggg attttttgtg gtagatagta ttatttttga
    25921 tttagatgga acattgtggg attcaactga agaagtatgc aaagtctggc aggatgtttt
    25981 aagtgagcat aaggaaatag aattaagtgt cacaaaagat ttatttagaa gtcttatggg
    26041 gctttctttt gaggaaatag caaatcgttt atttccaaat ttaagtgaag aagaaagaat
    26101 gaatttattg aatgaatgtt ctttgaaaga atgtgactat ttatctgaaa atggagctaa
    26161 attatttgat gatatagaag atactcttaa attactatct aaaaaatata aattatttat
    26221 agtaagtaat tgtcaagttg gatatataga atctttttta aaagcacata aactagaaca
    26281 gtattttata gattttgaat gtcctggtaa tactggtttg cataaaggag aaaataataa
    26341 acttataatt gaaagaaata aattaataaa tccaatctat gttggtgata cgcaaggtga
    26401 tgcaaatagt gctaagtttg taggtatacc ttttatatat gccaaatatg ggtttgggaa
    26461 tgtagatgta tatgattatt ttatagattc atttaaagat ttgttagaac atgatatatt
    26521 aaaataagat gagtttaaaa attatattaa aataataaaa aagttatggg gggatttaaa
    26581 aatggaatta caagatacta tttttaaaag acaaagtgta agaaagttta aaaatcaaga
    26641 tgtatcagat gaagatattt taaaaatgat aaaagcagca ggtgcagcac catcaggcaa
    26701 gaatattcaa aactggcatt ttgttgttat aaaacgccgt gatttaatgg aaaagatagc
    26761 agatgtgata actaaaaagc aacaagaaat acttgtagaa atggataaag tatcagtgga
    26821 taaggctaat agatttagaa aatttgttaa aaattttaca ctattttact taaaagctcc
    26881 agttttagta ttagttttta caaaggtata taatccatca ggatattatg aattagagct
    26941 tatagatgca cctaaggaga ctatagataa attatttata agaaatccag gtatgcagag
    27001 tctaggtgct gcaattgaaa actttacact atcagcaatt gaacttggat atggttcttg
    27061 ttggttgaca agtcaaaact atgcagcaga tgagatagaa gctgttttag aagcagaaac
    27121 tggttttgaa aagggagagt attttttagg tgcaatgtta gctcttggag tgccagagga
    27181 caatttgaag agtccatcta aaaaaccagt agaagaaata tgtacattta taaaataaaa
    27241 gtcaaggaca ttttaaaatc gaagtaaatt aaaaacaaaa taaattaaaa ataaatattt
    27301 aaaaaattaa aaagtaggtt ttattgatat taattttata tttcaaatca ttgattt
//
LOCUS       DAMKNB010000047        26465 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.049, whole genome shotgun sequence.
ACCESSION   DAMKNB010000047 DAMKNB010000000
VERSION     DAMKNB010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 26465)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26465)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26465
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.049"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            165..1040
                     /locus_tag="PC494_002250"
     CDS             165..1040
                     /locus_tag="PC494_002250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA glycosylase"
                     /protein_id="HDF3912747.1"
                     /translation="MNVYEKGNGVILEGVTDFDPVHIFECGQCFRWHKQEDGSYTGVA
                     KGRILNVKKENDKIYLNNTNLKEFNSIWYNYFDLGTDYTEIKNKLKNMDEYLNKATEF
                     GWGIRILRQDGWEMLISFIISSNNRIPMIQRAIENLSRKFGKYIGEYEGNEYYAFPTP
                     EELNKASQEEIRACQTGFRDKYIKSTTQAVIENNDEVSEYTNLSTEDCRKELLKFNGV
                     GPKVCDCIALFGMQKYDSFPVDVWVKRVMQEFYIDEDMSLPKMRTYGIDKFKEMSGFA
                     QQYLFYYARELGIGK"
     gene            1058..2548
                     /gene="cls"
                     /locus_tag="PC494_002251"
     CDS             1058..2548
                     /gene="cls"
                     /locus_tag="PC494_002251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HDF3912748.1"
                     /translation="MGVIGTIFLFYLIISYLAGAIISVIILLENRDPAKTMSWLLMFI
                     IFPGVGLMIYAISGRNIRKRKLFKTQKLANNIKEKKLFDTLEKITEIVELEKESIKQN
                     KLLRDEEDGSYRKRVINMLLKTGMFPFTKNNKVDVFVDGNEKFKRLIEDIREAKDHIH
                     LEYFIIKDSEIGRVLKEELIKKAKEGIKIRILYDDVGCWRFWFNRKFFREMREVGIEI
                     AAFLPTKFPIIGGKLNYRNHRKIVVIDGIIGYTGGINIGDEYLGKNDKFGYWRDTHIR
                     IKGISVYMLQMTFLIDWYYTTKEVLVTKNYFPSVGNVGESMIQVVASGPDSDWEDIHY
                     AYFSAICQARKNVYIETPYFIPDESLLKAIKSAALSGVDVRIIFPKIADHKIVNIASY
                     SYFEEILRAGGKVYLYNKGFIHSKVVIIDDKIASAGTANMDLRSFMLNFEVNAFIYDE
                     EVIRVMTDDFFEDLSYCEELNLEVFKNRNIIQKIKESVARLFSPIL"
     gene            2741..3025
                     /locus_tag="PC494_002252"
     CDS             2741..3025
                     /locus_tag="PC494_002252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012062101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HDF3912749.1"
                     /translation="MKIRPLADRVVIKKVEAEEKTASGIVLPGAAKEQPQIAEVVEVG
                     PGGIVEGKEIKMELTVGDKVIFQKYSGTEVKIEGQEYTILRQSDVLAVIE"
     gene            3058..4686
                     /gene="groL"
                     /locus_tag="PC494_002253"
     CDS             3058..4686
                     /gene="groL"
                     /locus_tag="PC494_002253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729227.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HDF3912750.1"
                     /translation="MAKEIKFSEETRRALEAGVNKLADTVKVTLGPKGRNVILDKKFG
                     SPLITNDGVTIAKEIELEDRFENMGAQLVKEVATKTNDVAGDGTTTATVLAQAIIREG
                     LKNVTAGANPILLRKGIQKAVTVAVEELKNQSRIVETQEAISQVASISAGDEEVGKLI
                     AEAMEIVGKDGVITVEESQTMNTELDAVEGMQFDRGFVSAYMVTDVDKMEAVLNDPYI
                     LITDKKISNIQELLPVLEQIVQQGKKLLIIAEDVEGEALSTLVVNKLRGTFDVVAVKA
                     PGFGDRRKEMLQDIAILTGAQVISEELGYDLKEADLSMLGRASSVKVTKESTTIVDGS
                     GDKKAIEDRVTQIKHQVEQTTSDFDREKLMERLAKLAGGVAVVKVGAATEVELKERKL
                     RIEDALNATRAAVEEGIVAGGGTAFVSVIPAIGTLIESLEGEVKLGAQIVKKALEEPL
                     RQIAINAGLEGAVIVQNVVNSEAETGFDALNEKYVNMIEAGIVDPTKVSRSALQNAAS
                     IASTFLTTEAAVADLPEKEDAGMPGMGGGMPGMM"
     gene            4948..5688
                     /gene="larB"
                     /locus_tag="PC494_002254"
     CDS             4948..5688
                     /gene="larB"
                     /locus_tag="PC494_002254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nickel pincer cofactor biosynthesis protein
                     LarB"
                     /protein_id="HDF3912751.1"
                     /translation="MDLRKLLEEVKNENIDIDFALEKLKDLPYEDLGYANIDHHRELR
                     NGYPEVIYCEGKSDEHILGIIDKMNQKSSNILGTRCRKETFLKIKEIYNHAEYEEASK
                     ILKIQNHDIENIGKGKIVIATGGTSDIPVADEAYHTAKFLGNDVDRIYDVGVAGIHRL
                     LNKRHKIDSARVIVAVAGMEGALASVIGGLVDVPVIAVPTSVGYGANFGGLAALLAML
                     NSCASGISVVNIDNGFGAGYLASMINKL"
     gene            5772..6506
                     /gene="larC"
                     /locus_tag="PC494_002255"
     CDS             5772..6506
                     /gene="larC"
                     /locus_tag="PC494_002255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nickel pincer cofactor biosynthesis protein
                     LarC"
                     /protein_id="HDF3912752.1"
                     /translation="MSEKILYFDIISGISGDMTLASLLNLGVPKEIFLEEIHKLRMSD
                     EFNINISSKTENGIVGTKVEVITKEKHTHRNLVDIFEVIDKSTLNENVKSKAKKIFMV
                     IGEAEAKVHGTTIDKIHFHEVGAIDSIVDIVGASILVDLLCVDKVCASTVSVGSGFVK
                     CEHGIIPIPAPATIEILKGVPIKLNNVNGECTTPTGAAIIKVLCDEFVDELEFSPKQI
                     GYGIGHKKFEVPNILRTVLGEKKKKN"
     gene            6536..6955
                     /locus_tag="PC494_002256"
     CDS             6536..6955
                     /locus_tag="PC494_002256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF111 family protein"
                     /protein_id="HDF3912753.1"
                     /translation="MSSEIYSYLYEKILDEKALDIYTESIYMKKNRPATKLSILCNES
                     DLEKFIKILLLETSTFGVRYNAYNREILERKFVKLDTKYGVVTVKLGYYKGKLVKATP
                     EYNECKTIAKNEDIPIKKVFADINFRIKEEFSENLLT"
     regulatory      7015..7116
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            7337..8872
                     /gene="guaA"
                     /locus_tag="PC494_002257"
     CDS             7337..8872
                     /gene="guaA"
                     /locus_tag="PC494_002257"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HDF3912754.1"
                     /translation="MKHELVLVIDFGGQYNQLIARRVRENNVYCEILPCTASIERIKE
                     KNPKGIIFTGGPNSAYLEDSPTISKEIFELGVPILGICYGIQIMSHVLGGVVRKGNKQ
                     EKEYGKTAITYGKSSLFEGITTNSVWMSHTDLIEKVPEGFTIVANTNDCPVAAMENVE
                     RNLYGVQFHPEVEHCLEGDKILTNFLYNICKVKGDWTTDSFIEDKIKELKEKIGDKKA
                     LCALSGGVDSSVAAVLIHKAIGDNLTCIFVDHGLLRKNEGNDVERIFREKFDINLIRV
                     NAEDRFLSKLKGVSEPEAKRKIIGEEFIRVFEEESNKLGKMDFLVQGTIYPDVIESGH
                     GNAATIKSHHNVGGIPEDVDFQEIVEPLRELFKDEVRKIGLELGIEEGLIFRHPFPGP
                     GLGIRVIGDVTKEKCDILREADAVYMDELRKAGLYREIWQAFATLPDVKTVGVMGDER
                     TYAYLVGLRAVTSSDGMTSDWYKMPYDVLERISNRIINEVDGVNRVVYDITSKPPGTI
                     EWE"
     gene            9411..10841
                     /locus_tag="PC494_002258"
     CDS             9411..10841
                     /locus_tag="PC494_002258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HDF3912755.1"
                     /translation="MILNQIFIEAGGIMRNKIIIGITFSLVLLMSGCASKQTAEINVL
                     ATTDLHGVIPYELTSYVKEERKKDKNLTLVDAGDFFDSGEVFGSSMDSYFSARYKDID
                     NNTERYIETPISKDMKEVGYDVAVLGNHEFISNNKFYLDNMISDFEKQKINILSANTY
                     KKNGDSYTKPYIIKNINTPEGNVKLGILGLTIKEVGERKQWKDGKLVDSKSLELKDQE
                     GYNGELYMNDLVEDAKKWVSIMEKEKPDIIVAVAHTGEKPKKPRNPGNRIQDLAQQVD
                     GIDAIVAGHNHVQIEQHDYKNKSGENVIVTEPGKHGECISKINFKLEKNNDKWNIVDK
                     SSKLIKFEKNQESDKFGEFISSINKVSKDKKEIRLSEVKTPEWDKIYVFKSGTSADDI
                     YKTIGYKWRNISSPKGDDMVQIVVMNNNKPVSYVYGEAEVMPINIKCDESEYKDNVVT
                     IYPNKNDKFKIEKGKQEYSINLKHIQ"
     gene            complement(10989..11339)
                     /locus_tag="PC494_002259"
                     /pseudo
     CDS             complement(10989..11339)
                     /locus_tag="PC494_002259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904812.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
     gene            11334..11855
                     /locus_tag="PC494_002260"
     CDS             11334..11855
                     /locus_tag="PC494_002260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromate transporter"
                     /protein_id="HDF3912756.1"
                     /translation="MFSIGGGYAIIPLIQEKVVNQTGWISEKMFTDIITISQMTPGPL
                     AVNTSTFVGLQIGGFWGAFAATLGCVLCGVVIALFLYNFFQKHQNSTYIFEILNGLKS
                     ASLGLIISAAATIIILALFGTNKVYFNSIFEMLNWTALIIFFVTLLIVRKWKINPIVI
                     IIISGILGIFFYL"
     gene            complement(11984..12778)
                     /locus_tag="PC494_002261"
     CDS             complement(11984..12778)
                     /locus_tag="PC494_002261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDF3912757.1"
                     /translation="MIFCNSFITRKSSMNIVVTHTPIVTTLEMQKAYEPLAKHNVNIF
                     AFDFSGTGKSDGYEKDFSRNSIVKDLDSVITYIEKNYSSNIHLYGNTGIGGMFAQYYA
                     CSDNKLKSFAQFACVDYKNTTGVGYTYLTVKLLNFFFKFLPNFHITVKPPKYKGYNEV
                     YDNEFYKIFEKKNPHIWKNSTKIINTMLECFIAEDSKIKDGVNIPTLVFKTLHDRYFK
                     TQYFDRYYNSLKCKKKLVEINNVHNSYYIDSEKFCQEAYDWFVENQ"
     gene            complement(13002..16430)
                     /gene="uvrA"
                     /locus_tag="PC494_002262"
     CDS             complement(13002..16430)
                     /gene="uvrA"
                     /locus_tag="PC494_002262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HDF3912758.1"
                     /translation="MKINNYKNQSIITNPKKFENKYQDLPKTPIELLKVVQSLVIHGD
                     QGKLYGISFNKQQSDEELLRTIPQMLKRIFEINSNPLTIPRNPKQRLVGMCRDYSLLL
                     VSLLRYRGFEARMRAGFANYFESELTYEDHWLVEYYDTLTKRWIRIDAQIDDIQKNYF
                     QINFDTHDVGKTDGFLTGSEAWIRCRQGHAHPDDFGYNKNWKGWHSVKGNLLHDFNNM
                     IGLELLPWDLWTELSSKKYNQLTRAEKNLLDEMAEILSSGNIKIEDLNLLIEKLPEDY
                     LKSIFSQLKILGISEIKELGNPLELEKKFKFTKSINKSIKNSLCHNKSSIYLKGGRQN
                     NLKDVEVTIPKNQITVITGVSGSGKSSLAFDTIYEEGKRRYFENLSNGAKLSEQLQKP
                     EFDLLQGLTPTIAIEQKKGSQNPRSTVGTLTSIWDYLRMLFVSIGKSYCPYCKIPLEK
                     KNNTKNYCPHCQTIFSKINTSTFNANSHTGACHDCNGLGFTYQVNPQLIVKDPTISIL
                     DGATYYFGKLRGKKPNGNWMVGELYAIAKDKNIDLDIPWNELPRDFIDAILYGTDDKI
                     YEFSFESKGRESKIRRPASGAINHIQRLFRESSSENNTLHQYMNKIPCNTCGGELLCI
                     EARFTTIKGYRFPELTKMTIEQLWNWLCELPNQLQKNELSLVNDILTELKIRVSYLLK
                     VGLSYISTDRTSPTLSGGELQRVRLSSQLGSELVGLTYILDEPSIGLHPRDHNLIIKM
                     IEELRDKGNTVIVVEHDKDTILSADYIIDVGPSAGTKGGFIIAEGTTQEIIKNPNSIT
                     GKYLSTYNKTGSQNKTIPSKWLSLKGCHANNLKNIDVEIPLNCMCSITGVSGSGKSSL
                     VFHSLLPALEEKLKQKSIPDKNYTEFTGFDAIDDFILMDQTPIGKSSRSTPATYINIF
                     DEIRSLFAETPQAKQKLLDESYFSFNSKKGQCPNCQGLGKTKIILQYMADQWVTCSEC
                     QGKRYQKEILSIQYKGKTIADILDMEVAEAKTFFSDCSDIYRKLSLLDEVGLGYLKLG
                     QNTLGLSGGESQRIKLAKELGTKTKKRMLYILDEPTTGLHFKDIENLLITFRKLVNEQ
                     HSLLIIEHNTEVIRASDWIIDIGPDSGINGGEIVASGTPDEIKINPNSITGHFI"
     gene            16749..18983
                     /locus_tag="PC494_002263"
     CDS             16749..18983
                     /locus_tag="PC494_002263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HDF3912759.1"
                     /translation="MKLSRYKKNSLVLSIILCSLIISILVITVFNTVKLHNISNKQSK
                     NYLNDVSTQIVMNVDSKIKFILSDLRIMADFIKQYEGDSRYEYLSKRKTSYKYYDVGI
                     IDLEGKAEFLSGKKFDLKNTASYKKGIEGKEYSEVIESMGFVLYSVPIFNDNHEVSSI
                     LIGVSNKESMNEILNIDNFNGEGTIEIINSKGKPLFIGKNTELIKDLSHKYKDSTDEP
                     WAQKMLNDFKNDKSGNITITSSKGVQCLLTYHPITRGLNDWHFLLIVPEDAVLGELNK
                     LNSFTITMTFIITCIIGIITLILYIIRRKYVNQIENIAYLDSITNGINSTKFSMLVKP
                     LISESPDSTYMMIAMNIKDFKLINDCFSSEKGNMTLKHLYNILYKNIDENEEFVCRHD
                     ADLFYLLIKNRPVLEALELLYKIEADTNYFNKNRENPYFLRLSVGIYTIENHNEDLIT
                     IQDHANTARKSFNKTHQSDFSFYSDIERKRLISEKEISNLMEKALENKEFFMCLQPKI
                     DIKSGKISGAESLVRWKNSEKGIIYPSDFIPLFEKSGFICKLDLYILEETCKLISKWI
                     KEGKEVLRISVNVSRQHLNDKLFLEKYKHICNKYNVPTCLIDLELTESIFLENPEAID
                     IIEDIHSNGFKCSIDDFGFGYSSLGILKDFKVDIIKLDRSFFVSKNNIDRGKVVIKSI
                     IELSKRLGMKVTAEGIEELEQVEFLKNVGCDYIQGYVFSKPLLISDFENFAYENNKIK
                     NIHY"
     gene            19239..21269
                     /locus_tag="PC494_002264"
     CDS             19239..21269
                     /locus_tag="PC494_002264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDF3912760.1"
                     /translation="MISGRMLLIMNFLKGKNKTSYKDISKQLSIEERKVRYDINNLNI
                     VLRSLNKSVIQKMNKGVLIIPDDFQVVCINNNEYVFSLTERVSIMKIISMFKIDNLNL
                     EKLSKEFQVSRSSIKNDLNVLSSELERNQITITYDKSFKISGEEDIIYKQRLNILKSY
                     SYLFGKEKSDLSVFEKYLVNVIEKIFKGIYLIDIYNWSMNLLLQMGWTLNDESFTWYV
                     SNIFLFTWYIHSDEKHPLESASLSEPCFENKFDQEFETIIQKKLTKEQIFLLKSFVFF
                     TNKYASLNEDMDLISTEIIVQDLIYNMSEILEISFKEDMILYKGLLNHIAPLIERIKQ
                     NIQIYEELLHVIPDKYQYVLEATKVSIQKNRVLSQIKNENETILLAIHFLGSIHRNER
                     NNYKNILLVCGFGYGVIAMLKDSLVNDYQINIVESIPSYKLQDYKEWESIDFIITTSK
                     IVIDLPKTIIEINPFLQEEDYLKFEEKGIKRKNVLTNYMSIKKRLDFLEEDAQKRVLS
                     IICQELGYSDERILFRQLNLSDLIGIDTIRIIDGDMKWEDAVKFSSNILANCDFVSAQ
                     YAENIIDILKNVGFYAVKDNEFALLHGNDSSLVKVSSISLLICKEAVSFGDKKVKIIF
                     CLASRDKKEQIPAIINLTKMVYKTNFIAMLESAKTKEEAEVLIHKYEKEVTV"
     gene            21266..21718
                     /locus_tag="PC494_002265"
     CDS             21266..21718
                     /locus_tag="PC494_002265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDF3912761.1"
                     /translation="MNKLVNVKCSFKIHVNSKEEAIISLVDVVSKEGYLIDKNQFLKD
                     VLKREETLSTYIGHGIGLPHSQSVGVKNSCITIGKLDTPIEWTEEGEKVDLIFLISVT
                     KDNENNLHLKILSKLARLLMHESFRNQIRCSDEQTVYNLIKEKIEEED"
     gene            21720..22775
                     /locus_tag="PC494_002266"
     CDS             21720..22775
                     /locus_tag="PC494_002266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit EIIC"
                     /protein_id="HDF3912762.1"
                     /translation="MRILKFLQKHLMTATSYMIPFVVAGGILFALSVTLSGQAAVPET
                     GWLAKLNQIGAAGLALFIPILGGYIAFSMADKPGLAPGMIGAYLAKEVNAGFIGGIIA
                     GFIAGFVVLQLKKIKLAPTMRTLGSIFIYPLIGTLITGGIIVFLIGEPIASFMTWMTN
                     WLNGMSGVSKIPLGGILGGMIASDMGGPINKVAATFAQTQVDTLPYLMGGVGVAICIP
                     PIGLGLATLLFPKKFSKEERDSGKASLLMGCVGITEGAIPFATSDPVRVIPCIMAGSI
                     IGNIMAFLLGCLNHAPWGGLIVLPVVDNRLGYIASVLTGAVVVAVLMKLVKKDVKEDE
                     EIEEDLDESIELIFEEL"
     gene            22842..23150
                     /locus_tag="PC494_002267"
     CDS             22842..23150
                     /locus_tag="PC494_002267"
                     /EC_number="2.7.1.202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose-like transporter subunit IIB"
                     /protein_id="HDF3912763.1"
                     /translation="MKIVAVTSCPSGVAHTYMSAESLELSAKKFGIEIKVETQGSSGI
                     DNELSLKDIDEATCVILTNDVEIRNMERFKGKKVVRMSVSEIIKKSDALIKKIKDTFQ
                     "
     gene            23254..24519
                     /locus_tag="PC494_002268"
     CDS             23254..24519
                     /locus_tag="PC494_002268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II D-tagatose-bisphosphate aldolase,
                     non-catalytic subunit"
                     /protein_id="HDF3912764.1"
                     /translation="MKKLPIKTVVQRLLNLQEEGKSATLLGIGPMSPNLLQASFELAK
                     DDDFPLMFIASRNQVDADELGGGYVNGWNQETFTKDIKKVADKVGFDGLYYLCRDHGG
                     PWQRDKERNDHLPVDEAMELGKKSYLADIEAGFDLLMIDPTKDPFEIGKVIPLDVVLE
                     RTVELIEYCENERKRLNLPDIGYEVGTEETNGGLTSTETYETFITRLKVELDNRGLPM
                     PTFIVGQTGTLTRKTEQVGIFNFRNAYDLAQMAKKYGVGLKEHNGDYLDDVTLLEHIP
                     SQIIATNVAPQYGTEETRAYLKLAEVECKLEKEGLVEKTSNIRHVLLVNAIECGRWRK
                     WVVGEQKNLTTEEIFKDEVLSNEILDIAGHYTFNNDDVKKEIEVLYDNLSKNNIDGQR
                     FVVDHIKRPLRDYAECYNLKGVTTRILNK"
     gene            24607..25323
                     /locus_tag="PC494_002269"
     CDS             24607..25323
                     /locus_tag="PC494_002269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HDF3912765.1"
                     /translation="MINLIFDVDDTLYNQLTPFYTAYNKVFSSIKDISIEDLYMSSRK
                     YSDEVFHMTENGEMPIKEMHIYRIMKAFEELGNSITEKDAQSFQDEYIYQQSQITLIP
                     EVERILNFSKERNINLGIITNGPSNHQRMKLKQLNIENWVDKSNIFISSEVGFSKPDT
                     NIFRVAENVMNLDRENTYYVGDSYRNDVLGAKKAGWKSIWLNHRGYEVEELFYKPDFV
                     ILEHKDLISLFIKICSYKNM"
     gene            complement(25518..25811)
                     /locus_tag="PC494_002270"
     CDS             complement(25518..25811)
                     /locus_tag="PC494_002270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore coat protein"
                     /protein_id="HDF3912766.1"
                     /translation="MRNMIENLIKNNTYIDDKVIMLSMLSSAKASANMYLNSALTSST
                     PELRAIYSASLTQMVEGHTALTELSINKGWVKPYDKPIQQLTCSYKESQNVID"
     gene            complement(25817..26032)
                     /locus_tag="PC494_002271"
     CDS             complement(25817..26032)
                     /locus_tag="PC494_002271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3912767.1"
                     /translation="MRILSETEKISLAAIIKMESDGLLMQRAINMLISDEDLKRQSES
                     SILATEGRIKAIQQFIVENEILISEEV"
BASE COUNT        10021 a         2953 c         4574 g         8917 t
ORIGIN      
        1 tttaaggtaa aaatttaaag taaaatatta ttttacataa taataacctt ataaattttg
       61 aaattactta tctttgtgtt aaaataagta aaatgcacat attagagcta agtttttaag
      121 taaataaaca aagtgaaaat ataaatatta aggagatttg gtatatgaat gtttatgaaa
      181 aaggtaatgg agttatacta gaaggagtaa cagattttga cccagtacat atatttgagt
      241 gtggtcaatg ttttagatgg cacaaacaag aagatggctc atacactgga gttgcaaagg
      301 ggagaatatt aaatgtcaaa aaagagaatg ataaaatata tttaaataat actaatttaa
      361 aggagtttaa cagcatttgg tataattact ttgatttagg aactgattat acagaaataa
      421 agaataagct aaaaaatatg gatgaatatt taaataaggc tactgaattt ggatggggaa
      481 taagaatatt aagacaagat ggatgggaaa tgcttatatc atttataatt tcctctaata
      541 ataggattcc tatgatacaa agagctatag aaaatttatc aagaaagttt ggtaagtata
      601 taggtgaata tgaaggcaat gaatactatg cattcccaac accagaagaa ctaaataagg
      661 cctcacaaga ggaaataaga gcatgtcaaa caggttttag agataagtac ataaaaagta
      721 ctacacaggc agttatagag aataatgatg aggtatctga atatacaaat ttaagtacag
      781 aggattgtag aaaagagctt ttaaaattta atggagtagg accaaaagta tgtgattgta
      841 ttgcattatt tggtatgcaa aaatatgatt cttttccagt tgatgtttgg gttaagagag
      901 ttatgcaaga attttatata gatgaagaca tgagtttacc taaaatgaga acctatggaa
      961 tcgataaatt taaagaaatg tctggatttg ctcaacagta cttattttac tatgcaagag
     1021 aactcggtat aggaaaataa attaaggggg agaaattatg ggagtaatag gaacaatatt
     1081 tctgttctat ttaattatat catatctagc tggagccata atttctgtga ttatattact
     1141 tgaaaataga gaccctgcaa aaacaatgtc ttggctattg atgtttatta tatttccagg
     1201 tgtaggttta atgatatatg ctatttcagg tagaaatatt agaaaaagaa aattatttaa
     1261 gactcaaaaa ctagctaata atataaaaga aaagaaacta tttgatacat tagaaaagat
     1321 aacagaaata gttgaattag aaaaagaatc tataaaacaa aataagcttt taagagatga
     1381 agaggatggt agttatagaa aaagggtaat aaatatgttg ttaaagactg gtatgtttcc
     1441 ctttactaaa aataataaag tggatgtatt tgtagatgga aatgaaaagt ttaaaagact
     1501 tatagaagat ataagagaag ctaaagacca tattcattta gagtacttta tcatcaaaga
     1561 tagtgaaata ggtagggtgt taaaagaaga acttataaaa aaggctaaag aaggcattaa
     1621 gataagaatt ttatatgatg atgtaggatg ctggagattt tggtttaata gaaaattttt
     1681 ccgagaaatg agggaagtag gtatagaaat tgcagcattt ttacctacaa aatttcctat
     1741 aataggaggg aaattaaact atagaaatca cagaaaaatt gttgttattg atggaataat
     1801 tggatataca ggtggaataa atataggaga tgaatattta ggcaaaaatg ataagtttgg
     1861 atattggaga gatactcata ttaggattaa gggtatttct gtatacatgc ttcaaatgac
     1921 atttctgatt gattggtatt atacgacaaa agaagtatta gtgactaaaa attatttccc
     1981 aagtgtaggg aatgttggtg aaagtatgat acaagttgtt gcgagtggtc cagacagtga
     2041 ctgggaagat attcattatg cttatttttc tgcaatatgt caggctagaa aaaatgttta
     2101 tatagaaact ccatatttta ttccagatga aagtctacta aaagctataa agagtgctgc
     2161 tcttagtgga gttgatgtga gaataatatt tcctaaaatt gcagaccaca agatagtaaa
     2221 tatagcatct tattcatatt ttgaagaaat attaagagca ggtggtaaag tttatttata
     2281 taataaagga tttatacatt ctaaagtcgt aataatagat gataaaattg cttctgcagg
     2341 tacagctaat atggatttaa gaagttttat gcttaacttt gaggtaaatg catttatcta
     2401 tgatgaagaa gttattaggg taatgacaga tgatttcttt gaggatttaa gttactgtga
     2461 agaacttaat ttggaggtat ttaagaatag aaatatcata caaaaaatca aagaatctgt
     2521 agcaagatta ttttcaccaa tattataaaa aattattaaa aaaggtattg aaaattatgt
     2581 gtgattggta tattataata attgttagca ctctattaga tagagtgata ataaataaaa
     2641 agtatatata taaatctaca tatataagta gtattaattt aaaaataact aaaaacatag
     2701 gcgaactagt ctatacttaa tattttagga ggcgtgaata atgaaaataa gaccattagc
     2761 tgacagagta gtaattaaaa aagtagaagc agaagaaaaa actgcaagtg gaatagtttt
     2821 accaggagca gctaaagagc aacctcaaat agctgaagtt gtagaagttg gaccaggtgg
     2881 aatagttgaa gggaaagaaa taaaaatgga attgacagtg ggagataagg ttatattcca
     2941 aaaatattct ggaacagaag ttaagataga aggacaagaa tacacaatac taagacagag
     3001 tgatgtatta gctgttattg aataaatata gaataaattt attaggaggg gtttaaaatg
     3061 gctaaagaaa ttaaattttc agaggaaaca agaagagctt tagaagctgg tgtaaataaa
     3121 ttagcagata cagtaaaagt aacattagga cctaaaggaa gaaatgttat attagataaa
     3181 aaatttggtt ctccacttat aactaatgat ggagtaacta tagcaaaaga gatagaacta
     3241 gaagatagat ttgaaaatat gggtgctcaa ttagttaaag aagtagcaac taaaactaat
     3301 gatgtagctg gagatggtac tacaactgct acagttttag cacaagctat aataagagaa
     3361 ggtttaaaga atgtaacagc aggggctaac ccaatacttt taagaaaagg aatacaaaaa
     3421 gcagtaacag tagcagtaga agaattaaaa aatcaatcaa gaatagtaga aacacaagag
     3481 gctatatctc aagttgcttc tatatctgct ggtgatgaag aagttggaaa attaatagca
     3541 gaagctatgg aaatagtagg taaagatgga gttataactg ttgaagagtc tcaaactatg
     3601 aatactgaat tagatgctgt tgaaggtatg cagtttgata gaggatttgt ttctgcatat
     3661 atggttacag atgtagataa aatggaagca gttttaaatg acccatatat attaattact
     3721 gataaaaaaa tatctaacat acaagaatta ttaccagttc ttgaacaaat agttcaacaa
     3781 ggtaaaaagt tattgataat agctgaagat gtagaaggtg aagcattatc tacattagta
     3841 gtaaataaat taagaggaac atttgatgta gtagcagtta aagctccagg ctttggagat
     3901 agaagaaaag aaatgcttca agatatagca atacttacag gtgctcaagt aatatcagaa
     3961 gaattaggtt atgatttaaa agaagctgat ttatctatgc taggtagagc ttcatctgtt
     4021 aaggtaacta aagaaagtac tacaatagta gatggttctg gagataaaaa agctatagaa
     4081 gatagagtaa ctcaaattaa acatcaagta gagcaaacta cttcagattt tgatagagag
     4141 aaattaatgg aaagattagc taaacttgct ggaggagtag ctgttgtaaa agttggagct
     4201 gctacagaag tagagttaaa agaaagaaag ttaagaatag aagatgctct taatgcaact
     4261 agagcagctg tagaagaagg aatagtagct ggtggaggaa ctgcttttgt tagtgttata
     4321 ccagcaatag gaacactaat tgagagttta gaaggagaag ttaaactagg tgctcaaata
     4381 gttaaaaaag cgttagaaga gccattaaga caaatagcta taaatgctgg tcttgaaggt
     4441 gctgtaattg tgcaaaatgt tgttaattct gaagcagaaa ctggatttga cgcattgaat
     4501 gaaaaatatg taaatatgat agaagctggt atagttgacc caactaaagt tagtagaagt
     4561 gctttacaaa atgctgcatc aatagcaagt actttcttaa ctactgaagc tgctgttgct
     4621 gaccttcctg aaaaagaaga tgcaggaatg ccaggaatgg gtggcggaat gcctggtatg
     4681 atgtaattta aaaaatttaa aatataaatt ttaatataaa gaactatttc gacttagatt
     4741 ttaaactcta agttgaaata gttcttttgt atatatctaa tttttgtata tctataaatt
     4801 caatacacat atttagataa tcagtatcta gtttgtaata atattttaga gtagtattgt
     4861 tattttttag gttatgattt tagatatata ttaattaagg tataattgtt gatagagaat
     4921 aaatcaaatt taaaaggatg cgataatatg gacttaagaa aattgcttga agaagttaaa
     4981 aatgaaaata ttgatataga ttttgcgtta gaaaagttaa aagatttacc ttatgaagac
     5041 cttggatatg caaatataga tcatcataga gaactaagaa atgggtatcc ggaagttatt
     5101 tattgtgaag gtaagagtga tgagcatatt ttagggatta ttgataaaat gaatcaaaaa
     5161 agttctaaca tattgggaac aaggtgcaga aaagaaactt ttctgaaaat taaagaaatc
     5221 tataatcatg ctgagtatga agaggcgtct aaaattctta agattcaaaa tcatgatata
     5281 gagaatatag gaaaaggtaa aattgtgatt gctacagggg gaacttctga tataccagta
     5341 gcagacgaag cttatcatac agctaagttt ttaggtaatg atgttgatag aatatatgat
     5401 gttggagtgg caggtataca taggctttta aataaaagac ataaaataga tagtgctaga
     5461 gtaatagtag ccgttgcagg tatggaaggt gctcttgcaa gtgtaattgg tggactggtt
     5521 gatgttccag taatagctgt tccaacttct gttggatatg gagcaaattt tggaggatta
     5581 gcagcattac tagctatgtt aaatagctgt gcatctggaa tatctgttgt aaatattgat
     5641 aatggatttg gagcaggata tttagcatca atgataaata aactgtaaat atattgatat
     5701 aaattaaaca aaactatata ataaaattta atttctatta tatttttact attaaaattg
     5761 aggagacata tatgagtgaa aaaatacttt attttgatat aataagcggt atatcagggg
     5821 atatgaccct tgcaagttta ttaaatttag gtgtgcctaa ggaaattttt ttggaggaaa
     5881 ttcataaact aagaatgagc gatgaattta atataaacat cagctcgaaa actgaaaatg
     5941 gaatagtagg tacaaaagta gaagtaatta caaaagaaaa acatacacat agaaatttag
     6001 tggatatatt tgaggttata gataaaagca ctctaaacga aaatgtaaaa tctaaagcaa
     6061 aaaaaatatt tatggtaatt ggagaagcag aagcaaaagt tcatggaact acaatagaca
     6121 agatacattt tcatgaggta ggggctatag attcaattgt agatatagta ggagcttcta
     6181 tattagtcga cttactttgt gtagataaag tttgtgctag tacagtgtct gttggttcag
     6241 gatttgtaaa atgtgaacat ggaattatac ctatacctgc acctgcaact atagaaattt
     6301 taaaaggtgt gccaattaaa ttaaataatg taaatggaga atgtacaact ccaacaggag
     6361 ctgcaatcat aaaagttttg tgtgatgagt ttgtagatga gcttgaattt tctccaaagc
     6421 aaattggata tggtataggt cataagaagt ttgaagtacc aaatatactc agaactgtat
     6481 taggtgaaaa aaaaaagaag aattaattta tgaaattagt gcaaacattg atgatatgtc
     6541 ttcagaaatc tattcttatt tgtatgaaaa aatattagat gagaaagcat tagatattta
     6601 tacagagagc atttatatga agaagaatag accagcaaca aaactatcaa ttttatgtaa
     6661 tgaatcagat ttagaaaaat ttattaaaat attactttta gaaactagta cttttggagt
     6721 gagatataat gcatataata gagaaattct agagagaaaa tttgtaaaat tagatacaaa
     6781 atatggagtg gttacagtaa aactagggta ttataaagga aaactagtca aggctactcc
     6841 agaatataat gaatgtaaaa ctatagcaaa aaatgaagat attcctataa aaaaagtgtt
     6901 tgctgatata aattttagaa taaaagaaga atttagtgaa aacttattga cataagtaat
     6961 aaattttgat aaattaatat tcagccttat taaataaaag taaacagaaa aaaatatata
     7021 aaatataaac tcactcgtat atgctcagaa atatggtctg agagtctcta ccaagatacc
     7081 gtaaatatct tgactatgag tgaaattatt ataccaaaag acctagttaa gtaaatgtgt
     7141 aggctgagtt aaactcccta tgtgttggct ataagataaa ggtattttgg aagcctgtat
     7201 agtaatttca cttttgctag aaattatgga agttactata caggtttttt gtgtaaaaag
     7261 atttaatata atttagactg tattgtgtta aaataaatat ataaaaacta tattatacaa
     7321 ggagagatgt aaatttatga aacatgaatt agtacttgta atagattttg gaggacaata
     7381 taatcagttg atagctagaa gagttagaga aaacaacgta tattgtgaaa tacttccatg
     7441 tactgcaagc atagaaagaa taaaagaaaa aaatcctaaa gggataatat ttacaggcgg
     7501 tccaaatagt gcgtatttag aagattctcc aacaatatca aaagaaatat ttgaactagg
     7561 agtaccaata cttggaatat gctatggtat tcaaataatg tctcatgtat tgggtggagt
     7621 tgtaagaaaa ggtaataaac aagaaaaaga atatggaaaa acagctataa cttatggaaa
     7681 atcatcatta tttgaaggaa taactacaaa tagtgtatgg atgagtcata cagatttaat
     7741 agaaaaagtt ccagaaggat ttactatagt tgcaaatact aatgattgtc cagtagcagc
     7801 tatggaaaat gtagaacgaa acctatatgg agttcaattc catccagagg tagaacactg
     7861 tttggaaggg gacaagatac ttacaaactt cttatataat atttgtaaag taaaaggtga
     7921 ctggactaca gattcattca tagaagataa aataaaagaa ttaaaagaaa aaataggcga
     7981 taaaaaagct ttatgtgctt taagtggagg agttgattct tctgttgctg cagttcttat
     8041 tcataaagca attggggaca acttaacttg tatatttgtt gaccatggtt tacttagaaa
     8101 aaatgaagga aatgatgtag aaagaatatt tagagagaaa tttgatataa atttaataag
     8161 agttaatgca gaagatagat tcttatctaa attaaaagga gtttctgaac cagaagctaa
     8221 gagaaaaata ataggtgaag aatttataag agtatttgaa gaagaatcaa ataaattagg
     8281 aaaaatggat ttcttagtac aaggaacaat ctatccagat gttatagaaa gtggacatgg
     8341 aaatgctgct actataaagt ctcatcataa tgttggtgga atcccagaag atgtagactt
     8401 ccaagaaatt gtagaaccat taagagagtt atttaaggat gaagttagaa aaataggatt
     8461 agagcttggt atagaagaag gattaatatt tagacatcct ttcccaggac caggtctagg
     8521 aataagagtt ataggtgatg taactaaaga aaaatgtgat atattaagag aagctgatgc
     8581 tgtttatatg gacgagctta gaaaagcagg tttatataga gaaatatggc aagcttttgc
     8641 aacattacca gatgttaaga ctgttggagt tatgggtgat gaaagaacat atgcttattt
     8701 agttggttta agagcagtta cttcttctga tggaatgact tctgactggt ataagatgcc
     8761 ttatgatgta ttagaaagaa tttctaatag aataataaat gaagttgatg gagtaaatag
     8821 agtagtttat gatataactt ctaagcctcc tggaactatt gaatgggaat aaaatataga
     8881 atgccaaaaa tccacataaa tacaggattt aaggtctctc ttacttctat gttatactgg
     8941 tttgatacta tcaatatttg ccagtatctt atggattaat aagcaaaaaa catcctgctg
     9001 aatgataaat tcagcggggt gtttttattt tgttttagaa ctcctttgct ctgaaactcg
     9061 aagtatttaa cactgatgat tttgttatct tttagttcct tttgtgtcat gctctgaaag
     9121 acaaattgat acaataaaaa agtaatttct taatcattga tggagatatg tatttatgtt
     9181 actcttgatg gtaatttgag taatattgtt catagctttt tatattcact taattagaga
     9241 atcatttggt ataatcataa ataaacttga tgatataata gaaaagattt ataattatta
     9301 gaagtatata aaagtatttt atgtctatga aatgtatgtc tataaaacat atagatgact
     9361 tttgtatatt aatgtatgaa tattgatatt atagaagaat tgagttgtca atgatactaa
     9421 atcaaatatt tatagaagct ggagggatta tgagaaataa aataattata ggaattactt
     9481 tttcacttgt attactaatg tctggatgtg cttcaaaaca aacagcagaa ataaacgtat
     9541 tagcaactac tgatttacat ggagttatac cttatgagtt aacttcttat gtaaaagaag
     9601 aaagaaaaaa agataaaaat ctaactttag tagatgcagg agattttttt gatagtggag
     9661 aagtgtttgg ttctagcatg gatagttatt ttagtgctag gtataaggat attgataata
     9721 acactgagcg ttacattgag acacctattt caaaagatat gaaagaggta ggttatgatg
     9781 ttgcagttct tgggaatcat gaatttatat ccaacaataa attttatcta gataatatga
     9841 tatctgattt tgagaagcaa aaaataaata ttttatcagc aaatacgtat aaaaaaaatg
     9901 gagacagtta tacaaaacca tacataataa aaaatattaa tacacctgaa ggaaacgtaa
     9961 aactaggaat tttagggctt actataaaag aagttggtga gaggaaacag tggaaagatg
    10021 gaaaacttgt tgactctaag tctttagaac taaaagacca agagggctac aatggtgaat
    10081 tgtatatgaa tgatttagta gaagatgcta aaaagtgggt tagtataatg gaaaaagaga
    10141 agcctgacat tatagttgct gtggcacata caggtgagaa acctaagaaa cctagaaacc
    10201 caggaaatag aatacaagac ttagctcaac aagttgatgg aattgatgct atagttgcag
    10261 gtcataatca tgttcaaatt gagcaacatg attataaaaa taaatcagga gaaaatgtta
    10321 tagttactga gccaggaaag catggagaat gtatttctaa gattaatttt aaattagaaa
    10381 aaaacaatga taaatggaat atagttgaca aatctagtaa attaattaaa tttgaaaaaa
    10441 atcaagaaag tgataaattt ggagaattta tttcttcaat taataaagta agtaaagata
    10501 agaaagaaat aagattgtca gaagtaaaga ctcctgaatg ggataaaata tatgttttta
    10561 aatctggaac atctgcagat gatatatata aaacaatagg atataaatgg agaaatatat
    10621 catctccaaa gggtgatgac atggtgcaga ttgttgtaat gaataataat aagcctgtta
    10681 gctatgtata tggtgaagct gaagttatgc caattaatat aaaatgtgat gaatcagagt
    10741 ataaagataa tgttgtaact atttatccta ataaaaatga taaatttaaa attgaaaaag
    10801 gtaaacaaga atatagtatt aatttaaaac atatacaata gaaactttta tcttatttaa
    10861 gtttagattg tacttaaaat aaagtgtgta ttattttaaa aattgatgat aattaaaatc
    10921 acaacattaa ggaatagtac acacttttta tgctaaaaaa tagaatgtta aaaaattaaa
    10981 cctttaaatt aaagtacatt gcttatatta tccaatatta tcttcaaagg ttgtgtgata
    11041 tttttatcct tatgtaatat tgctaacatt ttattttcca tatctatccc atctaattca
    11101 atcaatcgca attttttatg taagagtgaa tctaataata aattttctgg caaaatggtt
    11161 atacctaacc ctgcttctgc agctttaata agtgcaaaag aattaacact ttcccaaaca
    11221 ggataagctt tttggtttga aagagataat acactgtcca aagtattgcg aatggcactt
    11281 ccttgctcac gtaacaataa cggaaacgtg cataactgtc gtagagataa ggcttgttta
    11341 gtattggtgg tggttatgca atcatacctt taatccaaga gaaagtagta aatcaaactg
    11401 gatggataag tgagaaaatg tttacagata ttataactat ttcacaaatg acaccagggc
    11461 cactggctgt taatacttct acttttgttg gacttcaaat tggagggttt tggggagcat
    11521 ttgcagccac tttaggttgt gtattatgtg gtgtagtaat agctctattt ttatataatt
    11581 tttttcaaaa gcatcagaac tctacttata tatttgaaat attaaatggt ctaaaatcag
    11641 cttcattagg tttaattatc tcagctgcgg ctacaattat aattcttgca ttatttggga
    11701 cgaataaagt gtacttcaat tctatatttg agatgctaaa ctggactgca ctaataatct
    11761 tttttgttac actactgata gtacgtaagt ggaaaattaa tcctattgtg attataataa
    11821 taagtggtat actgggaata tttttttatt tataagtttt tgctaagtaa aggatatcta
    11881 tttttttata tcttaaatcc aaatagccaa taaagtaagg ctatttggat ttttaataaa
    11941 ttctgaaaaa ataatcagaa acccatataa catttaaatt atatcactgg ttttctacaa
    12001 accaatcata agcttcttgg caaaatttct cactatctat atagtaacta ttatgaacat
    12061 tattaatttc aacaagtttc tttttacatt ttagtgaatt ataatatcta tcaaaatatt
    12121 gggttttaaa atatctatca tgaagtgtct taaagacaag agtaggtatg ttgactccat
    12181 cttttatctt actatcttct gcaataaagc attctaacat tgtattaatt atctttgtac
    12241 tatttttcca aatatgagga tttttctttt caaatatttt ataaaattca ttatcataga
    12301 cttcattata acctttatat ttaggtggtt ttactgttat gtgaaaatta ggaagaaact
    12361 taaagaaaaa gtttaataat ttaacagtga gataggtata gcctactcct gttgtgtttt
    12421 tataatcaac acaagcaaac tgagcaaaac tttttaactt attgtctgaa catgcataat
    12481 attgtgcaaa cataccacca attcccgtat tcccatatag atgtatgttg gaagaataat
    12541 ttttttctat gtatgtaatg acagaatcta agtcttttac aattgaattg cgagaaaaat
    12601 ctttttcata tccatcactt ttccctgttc ctgaaaaatc aaaagcaaat atatttacat
    12661 tatgtttggc aagtggttca tatgcttttt gcatctcaag cgtagtgaca ataggagtat
    12721 gtgtaacaac aatattcatg gatgattttc tggtaataaa tgagttacaa aaaatcattg
    12781 tatctccatt tggtattttt atatgtttcc aactcatttg attttccttt ctctattata
    12841 aaatataata atttttatgt tctgttttat atattattca tattttatca cagataatat
    12901 actaaagtta atttttttat tgtacaccta ttataataat tcttctataa tataagacat
    12961 tctataattt tatatttaag ttcatgtgta tttaattgtt tttatataaa atgtccagta
    13021 atactatttg gatttatttt tatttcatca ggagttccag aagcaacaat ttcccctcca
    13081 tttattccac tgtctggacc tatatcgata atccaatcag aagcacgtat aacctctgta
    13141 ttgtgttcaa taattaaaag tgaatgctgt tcatttacaa gttttctaaa agtaattaac
    13201 aaattttcta tatctttaaa atgaagtcca gtagtaggct catccaatat gtacagcatt
    13261 cgttttttag tttttgtccc taattctttt gctaatttta tcctttgaga ttctcctcca
    13321 cttaatccta atgtattttg tccaagcttt agatatccaa gtcccacttc atctaataag
    13381 gagagttttc tatatatatc agagcaatcg ctaaaaaatg tttttgcttc tgctacttcc
    13441 atgtcaagta tatctgcaat tgtctttccc ttgtattgta tagacagtat ttctttttga
    13501 tatctcttac cttgacattc actacaagtt acccattggt ctgccatata ttgcagaata
    13561 atttttgttt tacctaatcc ttgacagttt gggcattgcc cctttttgct attaaagcta
    13621 aaatagcttt catccaataa tttttgtttt gcttgtggag tttcagcaaa tagagaacga
    13681 atttcatcaa aaatattgat atatgtagca ggtgtagaac ggctagattt tccaataggt
    13741 gtttggtcca ttaagataaa atcatcaata gcatcaaatc cagtaaattc agtataattt
    13801 ttatctggga tagatttttg tttcaatttt tcttctagag caggaagtaa actgtgaaat
    13861 acaagagagc tcttaccaga accactaaca cctgtaatag agcacataca gtttaaggga
    13921 atttctacat caatattttt taagttattt gcatggcatc cttttaagct taaccattta
    13981 cttggtatag ttttattttg tgaacctgtt ttattgtatg tacttaaata tttacctgtt
    14041 atagagtttg gattttttat aatttcttgg gttgtacctt ctgcaataat gaacccccct
    14101 tttgtaccag cacttgggcc tacatcaata atataatcag cagacagtat tgtatcttta
    14161 tcgtgttcga caactataac agtattaccc ttatctctta gctcttctat cattttgatg
    14221 attaaattat ggtctcttgg gtgtaaacca atagatggtt catctaaaat gtaggttaag
    14281 cctactaatt cacttcctag ctgacttgat aatcgtactc tctgcagttc tcctccagat
    14341 aaagttggag atgttctatc tgttgatata tagctaagac ctacctttaa tagataacta
    14401 actcgaattt ttaattctgt taagatatca tttaccaaag agagctcatt tttttgaagt
    14461 tgatttggta attcacacaa ccaattccat aactgttcta ttgtcatttt tgttagttca
    14521 gggaagcgat aacctttgat tgtagtgaat ctagcctcaa tgcacagcaa ttcgccacca
    14581 catgtattgc aaggaatttt gttcatatat tgatgcaagg tattattttc agaactagat
    14641 tctctaaaaa gtctttgaat gtggttgatt gctcctgaag caggtcttct aatctttgat
    14701 tctcgtccct ttgattcaaa gctaaattca tatatcttat cgtctgtacc atataagatt
    14761 gcatctataa aatctcttgg taattcattc caaggtatat ctaggtctat atttttatct
    14821 tttgctattg catataattc acctaccatc caattaccat ttggcttttt ccccctcaat
    14881 tttccaaaat agtaagtggc tccatctaat attgaaatag ttgggtcttt tacaatcaat
    14941 tgaggattaa cttgataggt aaaacctaat ccattacaat cgtgacaagc tccagtatgg
    15001 gagttagcat tgaaggttga agtatttatc ttagaaaaaa tagtttgaca atgcggacaa
    15061 taattttttg tattattctt tttttctaat ggaattttac aatatggaca gtaacttttt
    15121 ccgattgata caaataacat tcttaaataa tcccaaatgc ttgtaagagt accaacagta
    15181 gagcgaggat tttggcttcc ttttttctgt tcgatagcta tagtaggggt taatccctga
    15241 agtaaatcaa attccggttt ttgaagctgt tctgaaagtt ttgctccatt acttagattt
    15301 tcaaaataac gtctttttcc ttcttcataa atcgtatcga aagctaaaga agattttcca
    15361 ctaccactta cacctgtaat aacagttatt tgattttttg gaattgtaac ctcaacatcc
    15421 tttaaattgt tttgccttcc tccttttaaa tagatagagc ttttattatg acaaagtgaa
    15481 tttttaattg atttatttat tgattttgta aatttgaatt tcttttctag ttcaagagga
    15541 ttgcctaatt cttttatttc cgaaatacct aatattttta actgagaaaa gattgatttc
    15601 aaataatctt caggcaattt ttctattaac aaattaaggt cttctatttt tatatttccg
    15661 cttgataata tttctgccat ttcatctaat aaattttttt ctgctcttgt taattgattg
    15721 tattttttgg aacttaattc tgtccataaa tcccatggaa gcaattctaa accaatcata
    15781 ttattaaagt catgtagaag attacccttt acagaatgcc aacctttcca atttttatta
    15841 tatccaaagt catctggatg agcatgtcct tgccgacatc ttatccaggc ttctgaacca
    15901 gttaaaaaac catctgtttt tccgacatca tgagtgtcaa aattaatttg aaaataattt
    15961 ttttgtatgt catctatttg tgcatctatt cttatccatc tctttgttag agtatcatag
    16021 tattctacaa gccagtggtc ttcataagta agctcacttt caaaataatt agcaaaacct
    16081 gctctcattc tagcctcaaa acctcgatat cttaggagcg atacaagaag taaagaataa
    16141 tctctgcaca ttccaacaag cctttgtttt gggtttcttg gaatagttag tgggttagaa
    16201 tttatttcaa atattctttt taacatttga ggaattgtac gaagcaattc ctcatcagat
    16261 tgttgcttat taaaggatat accatataat tttccttggt ctccatgaat tactaggctt
    16321 tgaaccactt ttaataactc aattggagtc tttggtaaat cttgatattt attttcaaat
    16381 tttttaggat ttgtgatgat gctttgattt ttatagttat ttattttcat ttatatttca
    16441 cctctctaaa tggatgatat accctgacat ggtgtcatat gcaaggacaa tttaaatttt
    16501 ttgtccaaaa tttaaaaata aataaaaaat gatacagtga taaattgtaa tacaaatata
    16561 gtttcaaatt gcatataata taattattta ataaaaccat tatctatgga atgttaatga
    16621 aatgttaaga tggcattctt gaatattaag aaatagaata ctataatata gtgtgaagga
    16681 ttcttagtaa aaaaatttgt aagtgttaat atacattaaa aaataggttt ataatttgga
    16741 ggaaaaaaat gaaattatca aggtataaga aaaatagttt agttctgtct ataattttat
    16801 gttcacttat tatttcaatc cttgtaatta ctgtttttaa taccgtaaaa ctacacaata
    16861 tatctaataa acaatctaaa aactatttaa atgatgtatc tacacagatt gtaatgaatg
    16921 ttgattctaa aatcaaattt attttatccg acttaagaat aatggcagat tttattaagc
    16981 aatatgaagg tgatagtcga tatgagtatt tatctaaaag aaagactagt tataagtatt
    17041 atgatgttgg aataatagat ttagaaggta aagctgagtt tttaagtgga aaaaagtttg
    17101 acttaaagaa tactgcttcc tataaaaaag gaattgaagg taaagaatac tcagaagtaa
    17161 tagagtcaat gggttttgtt ctttatagtg tacccatatt taatgataat catgaagtat
    17221 ctagtatttt aataggtgta tccaataaag aaagtatgaa tgagattctt aatatagata
    17281 actttaatgg agaaggaact attgaaatta ttaatagtaa gggaaaacct cttttcatag
    17341 gaaaaaatac tgaattaata aaagacctta gccataaata taaggattct acagatgaac
    17401 cttgggcaca aaagatgctt aatgatttta aaaatgataa atcagggaat attacaataa
    17461 cctcatcaaa aggtgtacaa tgcttattga cttatcatcc aattacaaga ggtttaaatg
    17521 attggcattt tcttctcata gtacctgaag atgctgtact tggtgaactt aataagttaa
    17581 attcttttac aataacaatg acatttataa ttacatgtat tattggaatt ataacattaa
    17641 ttttatatat tataagaaga aaatatgtaa atcaaataga aaatattgca tatttagata
    17701 gtataacaaa tggcataaat tcaactaagt ttagtatgct agtcaaacct ttaatttcag
    17761 aatcacctga tagtacttat atgatgatag caatgaatat aaaagatttt aagctaataa
    17821 atgattgttt cagtagtgaa aagggaaata tgacactaaa acatctttac aatattttgt
    17881 ataaaaacat tgatgaaaat gaagaatttg tgtgccgtca tgatgcagac cttttctatt
    17941 tgcttattaa gaatagacca gtgttagaag ccctggagtt attatataaa atagaagctg
    18001 acacaaatta ttttaataaa aatagggaaa atccatactt tttaagacta tcagtaggta
    18061 tttacacaat tgaaaatcat aatgaagatt taattacaat acaagaccat gcaaatacag
    18121 caagaaaaag ctttaataaa actcatcaaa gtgatttttc tttttatagt gatatagaaa
    18181 gaaaacgatt aatatctgaa aaggaaattt caaatttaat ggaaaaagcc cttgaaaata
    18241 aagaattttt tatgtgctta caacccaaaa ttgatataaa aagtggaaaa attagtggag
    18301 cagagtctct tgtgcgttgg aaaaattcag aaaagggcat aatttatcca agtgatttta
    18361 ttcctctttt cgaaaaaagt ggatttatat gtaagttaga tttatatata ctagaagaaa
    18421 catgcaaatt gatttctaag tggataaaag aaggtaaaga agtgttgaga atttctgtta
    18481 atgtatcacg tcaacatctg aatgataaat tgtttttaga aaaatataag catatatgca
    18541 ataaatacaa tgtaccaaca tgtctgatag atttagaact taccgaatct attttcttag
    18601 aaaatccaga agctatagat ataatagagg atattcattc taatggattt aaatgttcta
    18661 tagacgattt tggatttggg tactcatcat taggaatatt aaaggatttt aaagttgata
    18721 taattaagtt agaccgttca ttctttgtta gcaaaaataa tatagaccgt ggtaaggtag
    18781 ttattaagtc tattattgaa cttagcaaaa ggctaggtat gaaagtaact gctgaaggaa
    18841 ttgaagaatt agaacaagtt gagtttctaa aaaatgtggg atgtgattat attcaaggtt
    18901 atgttttttc aaaaccatta ttaatttctg attttgaaaa ttttgcatat gaaaataata
    18961 aaattaaaaa tatccattat taaatgtaca agataaaaaa tttaggcaag ttatataatt
    19021 aaaaatataa cttgtctttt ttatttatat atttaataaa aatatatttg cagattttgt
    19081 aaaaataatt ttcaaatgtt gtaagttgtg gctaaagctt tattgtatta ttctgaatat
    19141 agaaagatag ttactgtctt agataaaaac tgaaacatac ataataatat aaaatttgct
    19201 atattaataa ctctaattat tttggaagga gggaaaatat gataagtggg agaatgttac
    19261 tcatcatgaa ttttctaaaa ggaaaaaata agacaagtta caaggatatt agcaaacaac
    19321 ttagtataga agaaagaaaa gttagatatg atataaataa tttaaatatt gttttgcgtt
    19381 cattaaacaa gtcagtaata caaaagatga acaaaggtgt gttaattatt cctgatgact
    19441 tccaagtagt atgtataaat aataacgaat atgtattttc cttaactgag cgagtatcta
    19501 ttatgaaaat tatatcaatg tttaaaatag ataatctaaa cttagaaaaa ttaagtaaag
    19561 aatttcaggt ttctagaagt tcaattaaaa atgaccttaa tgttttgtca agtgaattag
    19621 aaagaaacca aataactatt acttatgata aatcttttaa aataagtgga gaagaagaca
    19681 ttatatataa gcaaagattg aacatattaa aatcgtattc ttatcttttt ggtaaggaaa
    19741 aatctgattt aagtgtattt gagaagtatt tagtgaatgt aattgaaaaa atattcaaag
    19801 ggatttattt gattgatata tataattggt ctatgaattt attattgcaa atgggatgga
    19861 ctttaaatga tgaatctttt acatggtatg tgtcaaatat tttccttttt acatggtata
    19921 tacattcaga tgaaaaacat cctttagaat ctgcttcatt aagtgagccg tgttttgaaa
    19981 ataagtttga ccaagaattt gaaacaatta ttcaaaaaaa gttgactaag gaacaaattt
    20041 ttctgttaaa gagttttgta ttttttacaa ataaatatgc aagtttaaac gaggatatgg
    20101 atttgattag tacagaaatt atagttcaag atctaattta caatatgtca gaaatattag
    20161 agattagctt taaagaagat atgattcttt ataaaggatt actcaatcat attgccccat
    20221 tgatagagag aatcaaacag aatatacaga tttatgagga attacttcat gtaataccag
    20281 ataaatatca atatgtactt gaagctacta aggtttctat tcaaaaaaac agagttttaa
    20341 gtcaaataaa gaatgaaaat gaaacaatac ttttggcaat acatttctta ggaagtatac
    20401 atagaaatga gaggaataac tacaaaaata tattgttagt ttgtggattt ggatatggtg
    20461 taattgctat gttaaaggat agtttagtaa atgattacca gataaatata gtagagagta
    20521 ttccatcata taagttacaa gattataaag aatgggaaag tattgacttc attataacaa
    20581 catcaaagat agtaatagac ttgcctaaaa caattattga gataaatcca tttttacaag
    20641 aagaggatta tttgaagttt gaagaaaaag ggataaaaag aaagaacgtc ttaactaatt
    20701 atatgtcaat aaaaaaaagg ttggactttt tagaagaaga tgcccaaaaa agagtattaa
    20761 gtattatatg tcaagaactt ggatacagtg atgagagaat attatttaga caacttaatt
    20821 taagtgattt aatagggatt gataccataa ggataattga tggagatatg aaatgggaag
    20881 atgctgtaaa atttagttca aacatacttg ctaattgtga ttttgtatca gcacaatatg
    20941 ctgagaatat tatagatatt ttaaaaaatg tgggttttta tgctgtaaaa gataacgaat
    21001 ttgctttact acatggcaat gatagttcat tagtcaaagt aagttcgata agtttattaa
    21061 tatgtaaaga agcagttagt tttggagata aaaaggttaa aatcatattt tgcctagcaa
    21121 gcagagataa aaaagagcaa attcctgcaa taattaatct aactaaaatg gtttataaga
    21181 ctaattttat tgctatgtta gaaagtgcaa agacaaaaga agaagcagaa gttttaattc
    21241 ataaatatga gaaggaggtc actgtatgaa taaattagtt aatgtaaaat gttcatttaa
    21301 aatacatgtt aattcaaaag aagaagccat tatatcgtta gttgatgtag tgtcaaaaga
    21361 aggatattta atagataaaa atcaattttt aaaagatgtt ttaaagagag aagaaacatt
    21421 gtcgacttat attggacatg gtataggtct tcctcatagt caaagtgtag gtgttaaaaa
    21481 ctcttgtatt acaataggaa agcttgatac tcctattgaa tggacagaag aaggagaaaa
    21541 agtggattta atatttttga tatcagtaac aaaagacaat gaaaataatc ttcatttaaa
    21601 gattttatca aaattagcac gtttattgat gcatgaaagt tttagaaatc aaattagatg
    21661 ttcagatgaa caaactgttt ataatcttat aaaagaaaaa atagaggagg aagattaaaa
    21721 tgagaatttt aaagtttttg caaaaacatc ttatgacagc aacatcttat atgattccat
    21781 ttgtggttgc aggaggaata ttatttgctt tatcagtaac tctaagtgga caagctgctg
    21841 ttcctgaaac aggctggttg gctaaactga atcaaattgg agctgctggc ttggctttat
    21901 tcattcctat attaggtgga tatatagcat ttagtatggc agataaacca ggattagctc
    21961 caggtatgat aggtgcatat ttagcaaaag aagtaaatgc aggttttata ggtggtatca
    22021 tagcaggatt tatagcagga tttgttgttt tacaattaaa gaaaattaaa ttagctccta
    22081 caatgagaac tttaggttct atatttattt atcctttgat tggtacattg attacaggtg
    22141 gtataattgt atttttaatt ggagaaccta tagcttcttt tatgacatgg atgacaaact
    22201 ggttaaatgg aatgtctggt gtttctaaaa ttcctttagg tggaatctta ggaggaatga
    22261 tagcctcaga tatgggtggt cctataaata aggttgctgc tacttttgcc caaactcaag
    22321 ttgacacact tccatattta atgggtggag ttggcgttgc aatttgtata cctccaattg
    22381 gtttaggatt agctacatta ttgtttccaa aaaaatttag caaggaagaa agagattcag
    22441 gtaaagcttc actattaatg ggatgtgttg gaattacaga aggagctatt ccatttgcaa
    22501 catcagatcc agttagagta ataccttgta ttatggctgg gtcgattata ggaaatatta
    22561 tggctttttt attaggatgt ttaaatcatg caccctgggg aggcctgata gtattacctg
    22621 tagttgacaa taggttgggg tatattgcat cagtattaac tggagcagta gttgttgcag
    22681 tattaatgaa attagtaaaa aaagacgtga aagaagatga agaaattgaa gaagatttag
    22741 atgaatcaat tgaattaata tttgaagaat tataaatata aatggaagga atttgtataa
    22801 aaaagtaaat ataaaactat aaatttaaag gagataagaa tatgaaaatt gtagcagtaa
    22861 catcttgtcc tagtggagta gcacatactt acatgtcggc tgaatcactt gaattatcag
    22921 ccaaaaaatt tggtatagaa ataaaggttg agactcaagg aagttctgga atagataatg
    22981 aattgtcact taaagatatt gatgaagcaa cttgtgtaat attgactaat gatgttgaga
    23041 ttagaaacat ggaacgtttt aagggaaaga aggtagtaag aatgagtgta tctgagataa
    23101 ttaagaaatc tgatgcatta attaagaaaa taaaagatac ttttcaataa aaattgattt
    23161 attttacata taactcaaag atgtttttaa agaaattttt attaaaagca tctttgaaaa
    23221 tatcttaaaa atagaataaa aggagatata gtcatgaaaa agttaccaat aaagactgtc
    23281 gtacaaagat tactaaactt acaagaagag gggaaaagtg caactctttt aggaattggt
    23341 cctatgtcac caaacttgtt acaagcaagt tttgaactag caaaagatga tgattttcct
    23401 ttaatgttta tcgcaagtag aaatcaagta gatgcagatg aactaggtgg cggttatgta
    23461 aatggttgga atcaggaaac ttttacaaaa gatattaaga aggttgccga caaagttgga
    23521 tttgatggtt tatattattt atgtagagac catggtgggc catggcaaag agataaagag
    23581 agaaatgacc atttgcctgt tgatgaagca atggagttag gaaaaaaatc ttatttagcg
    23641 gacattgaag caggttttga cctattgatg attgacccta caaaagaccc atttgaaatt
    23701 ggaaaagtaa ttccactaga tgtagtacta gaaagaactg tagaattaat tgagtattgt
    23761 gaaaacgaga gaaaaagact taatctacca gacataggtt atgaggttgg tacagaggaa
    23821 accaatggag gtctgacttc aactgagacg tatgaaacat ttataactag actaaaggtt
    23881 gaacttgata atagaggttt gccaatgcca acatttatag ttggtcaaac tggtacttta
    23941 actagaaaga cagaacaagt aggaattttt aattttagaa atgcttatga tttagctcaa
    24001 atggctaaga aatatggagt tggtttaaaa gagcataatg gcgattactt agatgatgta
    24061 actttattag aacatatacc atctcaaatt attgctacaa atgtagctcc tcaatatggt
    24121 actgaagaaa ctagggcata tttaaaatta gcagaagttg agtgtaaatt agaaaaagag
    24181 ggcttagttg agaaaacttc taatatcaga catgttcttc ttgttaatgc aattgaatgt
    24241 ggacgttgga gaaaatgggt agtaggagaa caaaaaaatc taactactga agagatattt
    24301 aaggatgaag ttttatctaa tgaaatacta gatattgcag gacattatac atttaataat
    24361 gatgatgtta aaaaagaaat agaagtgctt tatgataatt taagtaagaa taatattgat
    24421 ggtcaaagat ttgttgtaga ccatattaaa cgtcctttgc gtgattatgc agaatgctat
    24481 aacttaaaag gtgttactac gaggatttta aataaataat aggacttata gtggtgagta
    24541 ttgttatact aggtatttat agttataatt atacttacca ctattaaatt taggaggact
    24601 aatattttga ttaatttaat ttttgatgta gatgatactt tatataatca attaacgcct
    24661 ttttacactg catataataa agtgttttct tcaataaagg atatttctat tgaagattta
    24721 tatatgagta gtagaaagta tagtgatgag gtatttcata tgactgaaaa tggagaaatg
    24781 ccaatcaaag aaatgcatat ttataggata atgaaagctt ttgaggagtt gggaaattct
    24841 attacagaaa aagatgcaca aagttttcaa gatgagtata tatatcaaca atcacaaatt
    24901 acactaatac cagaagttga gaggatttta aatttttcta aagaaagaaa tattaatcta
    24961 ggaattataa ctaatggccc atcaaaccat caaagaatga agttaaagca gttaaatatt
    25021 gaaaactggg ttgataaaag taatattttt atttctagtg aggttggatt ttctaagcca
    25081 gatactaata tttttagagt agctgagaat gttatgaatt tagatagaga aaatacatat
    25141 tatgtgggtg attcttatag aaatgatgta ttaggtgcta aaaaagctgg ttggaagagt
    25201 atatggttga accatagagg atatgaggta gaagaattgt tttataaacc tgattttgta
    25261 attttggaac ataaggattt gatatcttta tttataaaaa tatgtagtta taaaaatatg
    25321 tagtaaaaaa atgttaataa tagaattgta taaaataatt aataataact atataaaatt
    25381 atatgtttag attgtgagca atctatttta tattaaaaat agattattta gaagaagggg
    25441 aaatcttaaa aaaatttgaa tatccccttt ttattattta attaaaatga aatagttaga
    25501 aatatatttt atttagttta gtcaataaca ttttgggatt ctttataact acatgttaac
    25561 tgttgaatag gtttatcata tggtttaacc catcctttat taatacttaa ttctgtaagt
    25621 gctgtgtgac cttctaccat ttgagttaat gaagctgaat atatagctct taattcaggt
    25681 gtactacttg tcaatgcaga attaagatac atattggcag atgctttagc agatgaaagc
    25741 atacttaaca ttattacttt atcgtctata taagtattgt tcttaattag attttctatc
    25801 atatttctca tgttatctat acctcctcag aaattagtat ttcattttca actataaatt
    25861 gttgtatagc tttaattctt ccttctgttg ctaatatact agattctgat tgtcttttta
    25921 ggtcttcatc tgatattaac atatttattg ctctttgcat aagtaatccg tcagactcca
    25981 tttttataat tgctgctaaa gatatttttt cagtttctga aagtattctc atttaatcat
    26041 ctcctatatt gtaatttatg ctttaatagt atgtctttct tttcaaggaa ataaccatta
    26101 cactttttta cagtatttta tattctcttt atatcaaaat ttagtcgacc taatatatta
    26161 atataatttt gtaggatatt tatcattaaa tatctataaa ataaattatt tgaatattca
    26221 taaagcaaaa tttatttgta tgtacttctt caagagtcaa tatgagtttt ttcaaaaaat
    26281 taatttttat gataatcatt aagggctata tttttcttaa agttgtgatt atcattatta
    26341 atttacaata aaattgccga aaagccctct cctttaggtg tagggatgaa aggtaaggtc
    26401 ttaatataaa aaaagttaga ataatgcttg taatctaata ccgctactga taccctatat
    26461 ttagg
//
LOCUS       DAMKNB010000048        25742 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.050, whole genome shotgun sequence.
ACCESSION   DAMKNB010000048 DAMKNB010000000
VERSION     DAMKNB010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 25742)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25742)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25742
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.050"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            complement(<1..1025)
                     /locus_tag="PC494_002272"
     CDS             complement(<1..1025)
                     /locus_tag="PC494_002272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease domain-containing protein"
                     /protein_id="HDF3912768.1"
                     /translation="MKRVYIDFEMNMPNSKSKRAVFNSDIIAIGAVMYDEKTKNIDKF
                     KSLIRPVSNEELYPHIQELTHISSEELKSAPSYEEVMRKFKKWLGIFSDIKGIYTFGN
                     LDLTCFNNTDMRSAKKNNHPRFVNNIRDLFVDIKEKYINCGMRCMNYISLKNLLEFVN
                     LEFSGDAHDPLNDAYNLFILDEAITNNVDIQNLLIIRDIIRPPFNDINSNLDNCFNKF
                     KESLYKKEGNYNIVDFSVEIIKTVRMYLLTIIDVNIQNLEIMKDISKKMDTIDKLKDI
                     EEGYFYLLEDVYFDMKDVLEDLMLYRMNEDEYKYEIKNIIKMFDEDLDNEKIYINKCN
                     NLNVVNK"
     gene            complement(1073..1933)
                     /locus_tag="PC494_002273"
     CDS             complement(1073..1933)
                     /locus_tag="PC494_002273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011986089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiocytidine(32) synthetase TtcA"
                     /protein_id="HDF3912769.1"
                     /translation="MSELSGKGCEIIVPFEERLPVRDIEKSIIKKYRKNLWSKFMKAI
                     RDYKLVEEGDKIAVAISGGKDSILMAKMFQELKKHGQVNFDVEFIAMDPGYHANIRQL
                     LIDNCEYLNIPIHLFDSRIFEIADEIAKDYPCYMCARMRRGALYSKAEELGCNKLALG
                     HHYDDVIETTMLNLLCAGNFKTMLPKLNSTNFEGIKIIRPLYYIREEHIIRFIQNSGI
                     WPLNCACMVAAKKTGNKRYEIKDLIKSLESNFKNVEKSIFKAAENVNLDSVLGWQKDG
                     EKHSFLENFE"
     gene            2202..2411
                     /locus_tag="PC494_002274"
     CDS             2202..2411
                     /locus_tag="PC494_002274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore coat associated protein CotJA"
                     /protein_id="HDF3912770.1"
                     /translation="MENKTRDIKKNCGPSLARPYINNQIFTEMYCLSDALKFGTIFPE
                     LNLLESEMYNKELYAKPKKYRGGRR"
     gene            2411..2677
                     /locus_tag="PC494_002275"
     CDS             2411..2677
                     /locus_tag="PC494_002275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore coat protein CotJB"
                     /protein_id="HDF3912771.1"
                     /translation="MKDSSRAELMRKVQETSFACVDMNLYLDNHPDDKNAINTYNSLC
                     NQFAQARYAYENKYGPLTNFGYAPSRCPWQWADQPWPWDREFNY"
     gene            2706..3278
                     /locus_tag="PC494_002276"
     CDS             2706..3278
                     /locus_tag="PC494_002276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000265278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese catalase family protein"
                     /protein_id="HDF3912772.1"
                     /translation="MWIYQKTIQHPVNIKTCDPRMAKFLITQFGGPNGELAASLRYLS
                     QRYTMPTGNMRALLTDIGTEELAHVELICTMVYQLTSDASPEELKAAGLGSNYAQNGY
                     GIYPTDSNGVPFDVRPIAVMSNPVTDLHEDMAAEQKALATYYQLINLTDDVDVIDVLK
                     FLGQREIIHYQRFGEALMDAYELEESQKMF"
     gene            complement(3513..4703)
                     /locus_tag="PC494_002277"
     CDS             complement(3513..4703)
                     /locus_tag="PC494_002277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SH3 domain-containing protein"
                     /protein_id="HDF3912773.1"
                     /translation="MNFNQKRIAASIMATAIIMPTMGNLAYANESEVESVSIESRTIT
                     GNAVNFRKGPGTNHESMGKLYKGDKVEYVGKEGSWVKVKYNGNTGYVHGNYVAINSLG
                     SSNESSDTSVKSTKVVTAKGLNFRTGPSTSSSKISTLGYGTEVGYISESNGWSKISSN
                     GRVGYVSSKYLGTSVNDSTNENSENSSNDLVKGTKVVTAKSLNVRTGPGTSHSKIATL
                     SYGTEVGSISESGGWTKISYGNQTGYVSSQYLAEKGSVDTSIPSYSTNSPSQGADSVI
                     SFAKTLLGKPYVWGAEGPNSFDCSGFTQYVMKKSVGVSIPRVSRDQSKYGTYVNRGDL
                     RSGDLVFFDTQGSNNGSVSHVGIYIGNGDMIHASSGSSKKVTISNINSSYYSSRYVNA
                     RRVL"
     gene            complement(4963..5394)
                     /gene="dut"
                     /locus_tag="PC494_002278"
     CDS             complement(4963..5394)
                     /gene="dut"
                     /locus_tag="PC494_002278"
                     /EC_number="3.6.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HDF3912774.1"
                     /translation="MYNLKVKKLNDDAIIPNFAHKGDAGMDLYSIEEVVIPPGETKLI
                     KTGICIELPTMTEAQVRPRSGLALKHSVTVLNTPGTIDEGYRGELKIILINHGKNDFK
                     VEKHMKIAQMIVKPIYDINIEEVKELSDSERGKGGFGSTGF"
     gene            5507..7735
                     /locus_tag="PC494_002279"
     CDS             5507..7735
                     /locus_tag="PC494_002279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IA DNA topoisomerase"
                     /protein_id="HDF3912775.1"
                     /translation="MKLVLAEKPSVAKTIASFLGAKTRQDGYFEGNDYIITYAVGHLV
                     SLYDMKDYDKDKYSGSWKMNNFPFVPEDKFKFKIDSSKTKQFNTVKKLLNRKDVEYVI
                     NATDNDREGELIAFLIFLLAKNKKPVKRILVNEWTPEDITRGIKNLKDEDEMRNLQAA
                     GYTRLITDWLIGINFTSVATLKYGNGKLLNIGRVILPTVKLVYDRDMEILNFVPKTYY
                     EIEGHFKAEAGEYKGKYVKGKESKFDTLEDANKIIASITSETGKILDKKVTMSKEYAP
                     KLFSLTSLQGYITSKYSNFTSDKVLNVCQSLYEGNGKGGYITYPRTDSIFLEESLASK
                     ASQTLDKLKVGLEYENKIKFSKTKRVFDSSKVDSHSAIIPTYIIPKSLSKDEQLVYDA
                     IKDRFVANFMPPAEYENTEIKTEVDNCTFLTKGKVLKSKGYLEVYNKEEKNDLLPLVN
                     KDDVVDVLEIKPLTKQTTPPKPYTEDTLLKAMKNCGKNVPEEDTTVLSGYSIGTSATR
                     ADVLKKISQVGYVKKKGKSYSITDLGKNLVEIFPVKDLFDVDYTGKLEKSLSDIQKGK
                     YTRKEYLTNIISFIYQNVNIIKQDASKNINTEAYTFDSKTKKFTKTKEKKQKKDVTNT
                     EKEVAISKDSNNKKEVKNGDENQSLGKCPICQGDVLEFDKGFACKNHKECKFVIWKND
                     KYLSLYKKKVNKTMVKNILKKGETKVKSLTAKNGNKFDATLKYDKNPDTGYFNWKIEF
                     DN"
     gene            complement(7846..8331)
                     /locus_tag="PC494_002280"
     CDS             complement(7846..8331)
                     /locus_tag="PC494_002280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HDF3912776.1"
                     /translation="MDNNNILKIADSFLDFLFVLENNIFKESDLLKKFQNNSDIMKAY
                     FEECPMAPSHAKVILYLMTSNSSSISQIASNLGILKSNMTPIIDRLVEHGLVNKFPDP
                     KDRRILRVELTDKAFKLFDAVKAILKESLVKKLSNLSEEELTLLDEHTLKLSEIVKKL
                     G"
     gene            8583..9806
                     /locus_tag="PC494_002281"
     CDS             8583..9806
                     /locus_tag="PC494_002281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HDF3912777.1"
                     /translation="MKRYLIVFLMCSSLFLVGCGKTEESEPEKPIAVSVQKAIGGEIE
                     NTNSFSGTTKVKDETAVTAQTVGTVQEVYVKLGQNVRKGDELLSISSPELENSVKQSK
                     ASLDLAKASYSSATGGSLEAQVNQAKTALDNAKIQYEESQRNYDNNKILYEQEVISLD
                     QFKKIEFSLEQTKQQLDSAQRAYDTATSKSIPQAKALAKKQLDQAQVSYNLAMSNLDK
                     LTLTSPVDGTITAKNFDSKEMITQSQPAFIISNPNILEVDLNVAESDIGKFKKDGNVD
                     VIIEDQRILGKIDYVPSVVDPQTSLYPVKVLVNNTNNKFKAGMSAQVNLSVEKENGAV
                     TVPKKAIFEENGKKYVYIATKDNIAKKHLVQTGIVTEDKIEIKSGVSDKDTVIIGGIS
                     LISDGTKIFPVEKEK"
     gene            9810..12944
                     /locus_tag="PC494_002282"
     CDS             9810..12944
                     /locus_tag="PC494_002282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter permease subunit"
                     /protein_id="HDF3912778.1"
                     /translation="MNLTQTSVKRPLTIIMVFLVLIVFGGIGYKKMSINLMPDIEIPV
                     VMVMTTWTGAGPQDVDEQVSQKVDESLSAVSNVKSTISSSQESVSMVVAQFEFGTNLD
                     EIMNDVRSKVDALQTSLPDDAAKPTVLKLDMNAQAIGQLVISGGNENSSQALRKYAED
                     VIQPKIESIDGVTSADLKGGEKAQVNVIADPAVLSNYGVSLSTIKGVLSSSNKTFPYG
                     SITQGEDKIVLRAIDKLESLDDIKQIQIPVKGGNTVRLDNLCSVDYGYADKDSIYRYN
                     GKDSLVIDISKQQDANTVKVMQSAYKYVDELNKENPQFKIKIANDTSSYISESINSVM
                     SNLLISAVIAFIVIFAFLKSVRASLVVAVAIPISIIGAIAILYFTGESLNLITASSLV
                     ISVGMVVDNATVVIENIFKYRKSGRLSLDDCAIEGTRTVTNAILASTLTTIAIFLPIM
                     FTEGIAKITFGALGKTLIASLAFSFIGAITLVPSVFAKLSRGKNSQKMQEKDSPIFDK
                     VSEAYKKLLSVCLRHQRLVVISSLLIFVASLFGMGFIGMDFMPAADKGELSISIELPK
                     GLSLESNDYYVSMTEKKVSDIPEIKTLITTLTSDSNNSKASIAIELESQKNRKRTTDE
                     IEKEIIDRVATVPDCKINVSQNSSVMGGAGGADFTLEMKGPDLDVLKILGKEAEKEFS
                     SIKGFRNVETSLTDTTQEAQFTIDKHKAQEYGVNTAEIAGMLRTAINGDSVTTATIDD
                     YKVDVNLKFKADTIDSLEDIKQLKVNSATGKEVPLGAFSDIKMADGLQSISRTDGDFS
                     VNITATLDNLDAGTATKLALEKTNKMVIPKDYSIGVGGETEMMNESMASLGFSMVIAI
                     ALVYMVMVAQFESFSKPFIIMFCVPFAFVGVVLSLLVSGQSLSTVGMLGIILLIGIVV
                     NNGIVLIDYIEQLRKTNRNNDLIGLVSIGCAARLRPVLMTTATTILGMLPTALSLGEG
                     GETMQPLAIVIMGGLTVSTLITLVLIPTIYLIFDKWENKFSDKMPKIFGKITDKIGSI
                     KRKIIKKPKLKAKV"
     gene            12978..14276
                     /locus_tag="PC494_002283"
     CDS             12978..14276
                     /locus_tag="PC494_002283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TolC family protein"
                     /protein_id="HDF3912779.1"
                     /translation="MSKIVAIGCGVGIITANLIPVYADNNTSSINKVDNSILSDSNKR
                     TSEKEILTAREAVSAALKNSEKLKMKSEEIKMLKEKLEVQDEFDSFTGSDNSFPYDQI
                     GLLKNQSEQAKGFMEDQIANDITNKFNDLVSRENELDKIKNNLEIKTKEIKDMKLKKD
                     LGLVTSLETESAELELQTLQNTQKAKLQELKNNQDYFKLLTNIDLNNYQLDKEYRFES
                     FRVGGSVDSYMEGKVNEYLKYDQLILERTEESFNDKDENKADLPDRPNLTRPVAPTKP
                     EQGNLTDDEYKVLMDKYEKDYDRYKKEVEAYNLERQTYAAGLTTYANYLQQKFNTENG
                     LVTLEDSKKALKKGLIDSYAQLLALEDTIQITKKQLDLSEKQLKNTKLRYDLGLITLT
                     DYKKQVVSNEDAKNSYDSLIVNYNSLKNGIEKPWILNTGK"
     gene            complement(14565..14810)
                     /locus_tag="PC494_002284"
     CDS             complement(14565..14810)
                     /locus_tag="PC494_002284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HDF3912780.1"
                     /translation="MTKCPKCGKEVSSRPGSICPRCGFKVADESLKIRCPEPSCRALV
                     SRKLDYCPKCGCKLRGYNISEFVNMVRCKIDETFDKK"
     gene            complement(15024..17651)
                     /locus_tag="PC494_002285"
     CDS             complement(15024..17651)
                     /locus_tag="PC494_002285"
                     /EC_number="2.7.9.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate, phosphate dikinase"
                     /protein_id="HDF3912781.1"
                     /translation="METKYVYSFGEGSKDMKSLLGGKGANLAEMTKIGLPVPPGFTIT
                     TEACNDYYVNNESIRAEIIKEIEEHLATLEKDLNKTLGCNKNPLLVSVRSGAVFSMPG
                     MMDTILNLGLNDNSVVGLAEATQNERFAYDSYRRFIQMFSDVAMEVPKYKFENVLDRV
                     KEAKGYTVDTELTTDDLKEIVKEFKAIYKKEIKNDFPQDPKEQLMLAIEAVFRSWNNP
                     RAIVYRKLNDIAHNLGTAVNIQSMVFGNMGETSGTGVAFTRNPATGENKLFGEFLMNA
                     QGEDVVAGIRTPQNISTLADVMPAVFDEFVKITHILEGHYKDMQDIEFTIENERLYIL
                     QTRNGKRTAAAAINVAVDLVEAGIIDEKEAIMRIEPNQLDQLLHPKFEDKALKEAKVI
                     AKGLPASPGAASGKVYFNADDVVKANEKGEKVVLVRLETSPEDIEGMVKAEGILTARG
                     GMTSHAAVVARGMGKCCVAGCGEIKVDEFNKEIRALDDVVIKEGEYISIDGSTGNVYL
                     GDVKKTEVSLTGNFEKLMNWVDKHKCMMVRTNADNPRDARAAIEFGAEGIGLCRTEHM
                     FFDEARLPAVREMILSNTVEQREKALEKILPMQREDFVELFKVMDGKPVNIRLLDPPL
                     HEFLPHDDETIEELSKSMGIKVSDIKKRIVDLDEFNPMLGHRGCRLAITYPEICVMQS
                     KAIIQGAIEAIKAGVKVSPEIMVPLVGEVNELKIIRKMIVETVDAIIKEEGIEVPYTV
                     GTMIEIPRACLTADEIAQEADFFSFGTNDLTQMAFGYSRDDAGKFLGQYVDEEILEKD
                     PFQVLDQNGVGKLVKMGAKLGREVKPELKLGICGEHGGEPSSVEFCYSVGLNYVSCSP
                     FRVPIARLAAAQASIKNPR"
     gene            complement(17712..18554)
                     /locus_tag="PC494_002286"
     CDS             complement(17712..18554)
                     /locus_tag="PC494_002286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kinase/pyrophosphorylase"
                     /protein_id="HDF3912782.1"
                     /translation="MLVKNLIIYAVSDSVGETAQQVAKACMSQFYVNETYEIKRFPYM
                     INKGVLLETLENAKAENALIVYTLVDEELCSIVERYCEREGLSCIDLMTDILREISKR
                     TGRKPKREAGIIRKLDESYFKRVEAIEFAVKYDDGKDPRGVLQADIILVGISRTSKTP
                     LSMYLANKNIKVANVPLVPEIPIPKEVFEIDTKKIIGLTNSPEKLNEIRTQRLKALGL
                     SSKANYANLERILQELDYSEEIMKRIGCPVINVSNKAIEETAGIILDIMKENGLKIYK
                     EIEI"
     gene            complement(18561..19199)
                     /locus_tag="PC494_002287"
     CDS             complement(18561..19199)
                     /locus_tag="PC494_002287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF3912783.1"
                     /translation="MIIIQLNERQLKIIDIVKENEPITSESIASSLNVTRATLRSDLA
                     ILTMTGILDARPKVGYFYSGVSEINLIGKSVKEKTVEDIMSMPVLAKKDESIYDVIVT
                     MFLSDVGSIVIIDENEELCGVVSRKDLLKATIGGSDINKMPIGMIMTRTPNVVTLTKG
                     ASVLLASRKIIEHEVDSIPIVEYKGEDKNHMRVVGRISKTNITKLFLEIVDN"
     gene            complement(19635..20927)
                     /locus_tag="PC494_002288"
     CDS             complement(19635..20927)
                     /locus_tag="PC494_002288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HDF3912784.1"
                     /translation="MLDLNRKLAKLEEEGKKIKVALIGAGHMGNGMVSQMANMKGIEA
                     SIVVDINLELAHKAFTDAGIDEEIIDNVTNEKDAEIKLQEGKVLTCNDFLVACKTKSI
                     DVVIDATGGIAIGAEIALNSILNKKHIVMLNAETDCVVGPILKKLADDAGVIFTGSAG
                     DEPGAVMELFDFADAMGFEVRVIGKGKNNKLDLDCNPDTVREEAERKGASPHMIASFK
                     EGTKTMVEMALMCNATGFVPDVRGGHGIEATVNEVPKKYALKSEGGVLDNYGVVDFVN
                     GIAPGVFVVVAHKLKAVNDELKYLSMGDGPNYILYRPYHLCSLETPLSAAMAVLDHKA
                     TIVPKAGLVAEVMTIAKKDLKKGEFMDGYGAYTCYGTIEKYDVAKAMNAVPIGLISKK
                     TKVVKDIKKGEVITYDMVEIEKDTTLYHLRQLQEKIFG"
     gene            complement(20964..21320)
                     /locus_tag="PC494_002289"
     CDS             complement(20964..21320)
                     /locus_tag="PC494_002289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HDF3912785.1"
                     /translation="MKYEVKISGIGSLVKELMDESNCLIIYDETINDDDLKDISVIHS
                     IATLKSDVEIGDTLTIGNRDYCIVSVGDIAQKTLREIGHCTIKFDGKCEVNLPGEIHV
                     EIGNPDITIGDLITIS"
     gene            complement(21355..21714)
                     /locus_tag="PC494_002290"
     CDS             complement(21355..21714)
                     /locus_tag="PC494_002290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3912786.1"
                     /translation="MKLLVILFVAYILNTIFIMKQNKLYFKTLNRAKKKGDIVSTGKK
                     KSYFSKGSIAIISSDSDGFIKFGEILKGRTVMAKFKEIEEIEGLDIYSAEQKFKDEES
                     IVQAIKFIKEKINVSFN"
     gene            complement(21783..23756)
                     /locus_tag="PC494_002291"
     CDS             complement(21783..23756)
                     /locus_tag="PC494_002291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HDF3912787.1"
                     /translation="MSVTEKIPSIDRKIFKILIMCSKKEFVSINSIANELNVTTRSVR
                     TYIKQLNKDLGNDIAVIKYIKGQGYKLEIKDEQILNKIIDMNRKNVFSLNSKEDRVEF
                     ILNYLIELDGFITLDSLADEMCVGRTTLVNDFQYVEKVLASYNLNLIKKQNTGMKLNG
                     NELDIRLFILNQLYKNSRKDLSNSKYFKGIKKEEIINLEEKLLTLFKKNNFYVTDEML
                     REVINYIVVLVYRVKEEKKVKDYDVKFDLLKSYDEYFIAREIKHIISGMFECTLNDEE
                     IIYLTIPLVSGNAPASECALNSSRISKNIDELMENIFNQIYVDMGIFINEDELRVGLG
                     YHLSFTLNRLLFNIKLKNVLLEEIKQNCILPFKLAQIAGKVIEKKYNLEVSEDEIGYI
                     AIHFSGYLERNSSRFYSIKKIAIICSTGLGTAKLLKIRVEKLIGNNPKIDTLSSFNLR
                     NINLDEYDIVFTTIDLDTSNINTIVLKINTIFDENKLREQLKTVLCLREGNIDTTNST
                     NLLINNLLDEDKFMILNEKTILASLEKMMDHLMDLGCIDEKFRKNIVNREEKSPTVFD
                     KGLLFPHSINEKSDKFLMAVGILEEPIEYANRSIKIILMTMFPCENKIDSDLLVKIYE
                     EVLKIGQDVKLTNKISKCRTFLEFKKVLLKNLI"
     gene            complement(23978..24991)
                     /locus_tag="PC494_002292"
     CDS             complement(23978..24991)
                     /locus_tag="PC494_002292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIB"
                     /protein_id="HDF3912788.1"
                     /translation="MEENKILKIEKGTSGWGGPLYIKKEGNRNKILSMTAGGIHEVTL
                     KIKELLGCEIVDGFKTGVSDEEVAVVIIDCGGTARCGVYPKKKIPTINVNPVGKTGPL
                     AKFITEEYYVSDVNPNCISVVDGEDMPQKSQENKSENKSSIRKPDNYDEVKSKAQGEY
                     AKKNIILSIGQGAGQVVSKFYDAGRDTIQMVMNNVIPFMAFVSMLMGIILASGLGDWI
                     ARVISPLAGNIGGLLIISVICTLPFLSPILGPGAVIAQVVGTLVGTQIGLGAIPAYLA
                     LPALFAINGQAGCDFVPVGLSLGEAEPETVEYGVPALFYSRLITGPIAVIIAYGVAVF
                     ALR"
     gene            complement(25004..25549)
                     /locus_tag="PC494_002293"
     CDS             complement(25004..25549)
                     /locus_tag="PC494_002293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIC"
                     /protein_id="HDF3912789.1"
                     /translation="MENVITGLSKGAEWFIGLFQKGGEQFIGLVSGTLPTLIVLMVAI
                     NSLIKIIGEERVNNWASKLGKNSFTRYILLPLVSVFFLGNPMCYTFGRFLKEEHKAGF
                     YDAAVSFVHPITGLFPHANAGELFVWLGISAGLTTLGKETTTLALWYFIVGLIVIFIR
                     GIVTEKMYAFLTRKNRATNKA"
BASE COUNT         8810 a         4277 c         3270 g         9385 t
ORIGIN      
        1 atcttattaa caacatttaa gttattacat ttatttatat atattttttc attatctaag
       61 tcttcatcaa acatttttat tatatttttt atctcatact tgtactcatc ttcattcatt
      121 ctataaagca ttaaatcttc tagtacatct ttcatatcga agtacacatc ttctaataaa
      181 taaaaatagc cttcctctat atctttcaat ttatctatag tatccatttt tttacttata
      241 tctttcataa tttctaaatt ttgtatattt acatctatga ttgttaataa gtacattctc
      301 acagttttta ttatttcaac agaaaaatct acaatattat aatttccttc ttttttatat
      361 aatgactcct taaatttgtt aaaacaatta tctaaattag aatttatatc gttaaatggt
      421 ggtcttatta tgtcacgtat tattaaaaga ttttgtatat ctacattatt tgtgattgcc
      481 tcatccaaaa taaataaatt atatgcatca tttaatgggt catgggcatc tccactaaac
      541 tctaagttaa caaattcaag taaatttttc aatgatatat agttcataca tctcatacca
      601 caatttatat atttttcttt tatatctaca aataaatctc taatgttatt tacaaacctt
      661 ggatggttat tttttttagc acttctcata tctgtgttat tgaaacatgt caaatccaaa
      721 ttaccaaaag tatatattcc tttaatatca gaaaatatgc caagccattt tttaaacttt
      781 ctcatgacct cttcataact tggtgcactc ttcaattctt cagaagatat atgtgttaat
      841 tcttgtatat gaggatacaa ctcctcatta cttactggtc ttattaaaga tttaaattta
      901 tcaatatttt ttgttttttc atcatacata actgctccga ttgcaattat atcagaatta
      961 aatactgctc tttttgattt agaatttggc atattcattt caaaatctat atatactctt
     1021 ttcaatataa acaccctttc caattgttta tagtgattct ttttaactat ttttattcaa
     1081 aattttctaa gaaagaatgt ttctccccat ctttttgcca accaagtact gaatcaagat
     1141 ttacattttc tgccgcctta aatatagatt tttctacatt tttaaaattt gattctaagc
     1201 tctttattaa gtcttttatc tcatatcttt tattacctgt ttttttagca gcaaccatac
     1261 atgcacaatt taatggccat ataccactat tttgaataaa tcttataata tgttcttctc
     1321 ttatataata aagtggtctt ataattttta taccttcaaa attagtagaa ttaagtttag
     1381 gaagcattgt tttaaaattt ccagcacaca ataaattaag cattgttgtc tctattacat
     1441 cgtcataatg atgacctaat gcaagtttgt tacaccctaa ttcttctgcc tttgaatata
     1501 atgctcctct cctcattctt gcacacatat agcatggata atcttttgct atttcatctg
     1561 ctatctcaaa tatccttgaa tcaaataaat gtattggtat atttagatac tcacaattat
     1621 ctataagtaa ttgtcttata tttgcatgat atccagggtc catagcaata aattcaacat
     1681 caaaattaac ttgtccatgt ttttttaact cttgaaacat tttagccata agaatactgt
     1741 cttttccacc agaaatcgct acagctatct tatcaccttc ttcaaccaat ttataatctc
     1801 ttattgcctt cataaactta gaccataaat ttttcctata tttttttatt atactttttt
     1861 ctatatctct tactggaagt ctttcctcaa aaggaactat aatttcacag ccttttcctg
     1921 atagttcact catctaatca cctcgtatat ttatgttaat aatattttac aaaaaagtct
     1981 accttcatcc acaaaatact ataattttta ctttaatttt actaaataat ttatagttta
     2041 caataacaca taaacttata ataacataaa taacctcttt cttttattat cttttttatt
     2101 tttctcattt aatattttat tattagtaac gatttttaaa tgattgaata ttatacacta
     2161 gatagagtta cctatctatt tacaacaagg aggttttcat cttggaaaat aagactagag
     2221 atatcaaaaa aaattgtggt ccatctttgg ctagaccata cattaataat caaattttca
     2281 cagaaatgta ctgcctttct gatgcattaa aatttggaac tatatttcca gaactaaact
     2341 tactagagtc tgaaatgtac aacaaagaat tatatgctaa gccaaaaaaa tatagaggag
     2401 gtagaagata atgaaagact catctagagc tgaacttatg agaaaagttc aggaaacatc
     2461 ttttgcatgt gttgatatga acttatattt agacaatcac cctgatgata aaaatgctat
     2521 caacacttat aattcattat gtaatcaatt tgcgcaagct agatatgctt acgaaaataa
     2581 atacggtcct ttaactaact ttgggtatgc tccaagtaga tgcccttggc aatgggctga
     2641 ccaaccttgg ccttgggaca gagaatttaa ttattagaca tcaagtattg gaggattgaa
     2701 aattcatgtg gatatatcag aaaactatac aacacccagt taatataaaa acttgtgacc
     2761 ctagaatggc taaatttctt ataactcaat ttggtgggcc aaatggagaa cttgctgcat
     2821 ctttaagata tttaagccaa agatatacaa tgcctactgg taatatgcgt gcacttttaa
     2881 cagatattgg tacagaagaa ctagctcacg ttgagcttat atgtactatg gtttatcagt
     2941 taacttctga tgcaagccca gaagagttaa aagctgcagg tcttggttca aactatgctc
     3001 aaaatggata tggaatttat ccaacagatt caaatggtgt tccatttgat gtaagaccta
     3061 tagcagttat gtcaaatccc gtaaccgatt tacatgagga tatggcagct gaacaaaaag
     3121 cacttgcaac ttattatcaa cttataaacc taacagatga cgttgatgtt atagatgtat
     3181 taaaattctt gggtcaaaga gaaataattc attatcaaag atttggtgaa gccttaatgg
     3241 atgcttacga gttagaagaa tctcaaaaaa tgttctaaaa tttttatttg tataactatt
     3301 attatttgat aatttataat ttactgttgt gttaaaattt ataaaaaata taaatataat
     3361 ttattttcta taaacagaga aaataaataa aaagcaggta tcaatcaaat agtaacatgt
     3421 attatactat acattactat caatattgta cctgctttca tattataagc aataaagaaa
     3481 aatctattta ttaggtttta taataaaaac aattataaaa ctcttcttgc atttacatat
     3541 ctacttgaat agtagctact atttatatta gatattgtta ctttttttga tgaacctgaa
     3601 gatgcatgta tcatatctcc atttcctatg tatattccaa catgacttac agaaccatta
     3661 tttgaacctt gtgtatcaaa gaatactaaa tctccacttc taaggtctcc tctatttaca
     3721 tatgttccat acttactttg gtctctagat actcttggta tactaactcc tacagatttt
     3781 ttcataacgt actgcgtgaa tccagaacag tcaaaactat ttggaccttc tgctccccat
     3841 acatatggtt ttccaagtag tgtctttgca aaacttatta cactatcagc tccttgactt
     3901 ggagaattag tcgaataaga tggaattgaa gtatcaacag aacctttttc agcaaggtat
     3961 tgacttgaca catatccagt ttgattgcca taacttattt ttgtccatcc tccactttca
     4021 gaaatacttc caacctcagt accataactt aatgtagcta ttttagaatg acttgtacct
     4081 ggtcctgttc taacgttcaa tgactttgct gttacaacct ttgtaccctt tacaaggtca
     4141 tttgaactgt tttcagaatt ttcatttgta gagtcattta cactagttcc taaatattta
     4201 cttgaaacat aacctactct accattagaa cttatttttg accatccatt tgactcagat
     4261 atgtatccga cttcagtccc atatcctagt gttgatattt tagaactact tgtacttggt
     4321 cctgttctaa aatttaatcc ttttgctgtt acaacttttg tcgacttaac tgaagtatca
     4381 ctactttcat tgctacttcc aaggctattt attgctacat aatttccatg cacataacct
     4441 gtgtttccat tatatttaac ttttacccaa gaaccttctt ttcctacgta ctcaacttta
     4501 tcacctttgt aaagtttccc cattgattca tggtttgtac ctggtccttt tctaaaattt
     4561 accgcattcc ctgttattgt tctgctttct atactcacac tctctacttc agactcatta
     4621 gcatatgcta aattccccat agtaggcatt attatcgcag ttgccattat actggctgct
     4681 attctctttt gattaaaatt cataactttc cactcatctc ctcttttcta ctatctttat
     4741 ttcacttcaa aatataaaag aaataattga cactatcaaa atatcaatta tttcttttat
     4801 attaatatta ttacaaattt gtaactattt gtctatagta atatttgctt accataaatt
     4861 accatgtata aattttaatc tttaatagcc tgtaatttag taatatagcc atcttttacc
     4921 ttttttaaaa atggctatat tttttaactt ttttgtaact ttttaaaatc cagttgagcc
     4981 aaacccacct tttcctcttt cggagtcact taattctttt acttcttcta tgttaatatc
     5041 atagataggt tttactatca tttgagcaat tttcatatgc ttttcaacct taaaatcatt
     5101 tttaccatga tttattaata taattttaag ctctcctctg tatccttcgt caatagttcc
     5161 tggtgtattt aatacagtaa cagaatgctt taaggcaagc ccacttctag gtcttacctg
     5221 cgcttctgtc atagtaggaa gctctataca tatcccagtt ttgataagtt tagtctctcc
     5281 aggaggtatt acaacctctt ctatagaata caaatccata ccagcatcac ctttgtgagc
     5341 aaaattaggt attatagcat catcatttaa tttttttact tttaaattgt acatcttata
     5401 tctcctttca actttctata aatattataa cttaaatttc gacctcttga agttttttat
     5461 ttttttgtgg taatataatt attagtgttt taaaggagga ttttttatga aacttgtact
     5521 tgctgagaaa ccatctgtgg caaaaactat agcatcattt ttaggtgcaa agaccagaca
     5581 agatggttac tttgaaggaa atgattatat aattacttat gcagttggac acttagtatc
     5641 attatatgat atgaaggatt atgataaaga taaatactct ggctcttgga aaatgaacaa
     5701 tttcccattt gttcctgagg ataagtttaa atttaagatt gatagttcta aaactaaaca
     5761 attcaacact gtaaaaaagc ttttgaatag aaaagatgta gaatatgtaa taaatgccac
     5821 tgataatgac cgagaaggag aacttatagc atttttaata tttttactgg caaaaaataa
     5881 aaaaccagta aaaagaatct tggtaaatga atggacacca gaagatatta caagaggtat
     5941 aaaaaaccta aaagatgaag atgaaatgag aaatcttcaa gctgctggat atactaggct
     6001 tattactgac tggttgattg gaataaattt cacttctgtt gctacattga aatacggaaa
     6061 tgggaaacta ttaaacatag gtagggtaat tcttccaaca gttaaattag tctatgatag
     6121 agatatggaa atactaaact ttgttcctaa aacttattat gaaatagaag ggcattttaa
     6181 agctgaagct ggtgaatata aaggtaaata tgttaagggt aaagaaagta aatttgatac
     6241 acttgaagat gcaaataaaa ttatagcttc aattacatct gaaactggta aaatactaga
     6301 taaaaaagtt actatgtcaa aggaatatgc accaaaactt tttagtttga catcacttca
     6361 aggatatata acttctaagt attccaattt tacatctgat aaggttttaa atgtctgtca
     6421 atctctctat gagggtaatg gtaagggtgg atacataact taccctagaa ctgattccat
     6481 tttcttagaa gaaagtttgg cttcaaaagc ttctcaaact ttagataaat taaaggttgg
     6541 tcttgaatat gaaaataaaa ttaaattttc taaaactaaa agagtttttg attcttctaa
     6601 agtagactcc catagtgcta taattccaac ttatataatt ccaaaaagtt tatctaagga
     6661 tgaacaatta gtttatgatg ccataaaaga tagatttgta gcaaacttta tgcctcctgc
     6721 tgaatatgag aatacagaaa ttaagactga agtagataat tgtactttct taacaaaagg
     6781 taaggtgctt aaatcaaaag gataccttga ggtatataat aaggaagaaa aaaacgattt
     6841 acttccactt gtaaataaag atgatgttgt agatgtgtta gaaataaaac cattaactaa
     6901 gcaaactact ccacctaaac cgtatactga ggacacactt ttaaaggcta tgaaaaattg
     6961 tggtaaaaat gtgcctgaag aagatacaac agtgctatct ggatattcga ttggaacatc
     7021 agccacacgt gctgatgtgt taaagaagat aagtcaagtg ggctatgtaa agaaaaaagg
     7081 taaatcttat tctataacag accttgggaa aaatttagtt gaaatttttc ctgttaaaga
     7141 cttatttgat gtagattata ctggaaaact tgaaaaaagt ttaagcgata ttcaaaaagg
     7201 aaagtataca agaaaagaat atcttactaa tatcattagt tttatatatc aaaatgtcaa
     7261 tattataaaa caagatgctt caaaaaatat aaacacagaa gcatatactt tcgattcaaa
     7321 aactaaaaaa tttactaaaa caaaagaaaa aaaacagaaa aaagatgtaa ctaatactga
     7381 aaaagaagtt gctatatcaa aggattctaa taacaaaaaa gaagttaaaa atggtgatga
     7441 aaatcaatct cttggcaaat gccccatttg tcaaggtgat gtactagaat ttgacaaagg
     7501 ctttgcttgt aaaaatcata aagaatgtaa atttgttatt tggaaaaatg ataagtattt
     7561 aagtctttat aaaaagaaag ttaacaaaac aatggtcaaa aatattttaa aaaaaggtga
     7621 aactaaagta aaatctttaa ctgctaaaaa cggtaataaa tttgatgcta cattaaaata
     7681 tgataaaaat ccagatactg gctatttcaa ttggaaaata gagtttgaca actaaatatt
     7741 cataagaaaa gaaatagcag tagtataata atctatatta tattactgct atttcttttc
     7801 ttatgaagtt tcaacttttt taatagtgac ttttacaatc acactctaac ctaatttctt
     7861 tactatttct gataacttta atgtatgttc atctaataaa gttagttcct cttcagaaag
     7921 attagataat ttttttacta gagattcttt gagaatagct tttactgcat caaataattt
     7981 aaatgcttta tctgttaatt caaccctaag aatccttcta tcttttgggt caggaaattt
     8041 attgactaaa ccatgttcca ctaatctgtc aataatcgga gtcatatttg attttaaaat
     8101 tcctaaatta gaagctattt gagaaattga tgatgaattt gatgtcataa gataaagaat
     8161 taccttagca tgtgatggag ccattggaca ttcttcaaaa taagctttca ttatatcaga
     8221 gttattttga aactttttta acaaatcgct ttctttaaat atattatttt caagcacaaa
     8281 taaaaaatct aaaaaagagt ccgctatttt aagtatattg ttgttatcca tatttgtaac
     8341 atcccttcaa tagataatat aataaaacat tgttgtttaa tatagtataa attataaact
     8401 attaataaat ttaaaacaag aaaaagttat tgactcataa taattataaa tttataatca
     8461 aattagagaa ttataaattg ccaataaagg gaagtttttt aattagtcta aaactaaact
     8521 taaattataa gacactttaa attctacaac aagctagtgt gcaatatata ataggaggag
     8581 atatgaaaag atatttaata gttttcttaa tgtgtagttc actgttttta gttggatgtg
     8641 gaaaaacaga agaatctgaa cctgagaaac caatagcagt ttctgttcaa aaagcaatag
     8701 gtggagaaat tgaaaacaca aattctttct caggaactac aaaggttaaa gatgaaacag
     8761 ctgttactgc acagactgtt ggcacagttc aagaagtgta tgtaaaactt gggcaaaatg
     8821 taagaaaagg agatgaatta ttgagtataa gcagtccaga gctagaaaat agtgtaaagc
     8881 aaagtaaagc ctcactagat ttagcaaaag caagttattc aagtgccact ggtggttcat
     8941 tagaggcaca agtaaatcag gcaaaaacag ctcttgacaa tgcaaagatt caatatgagg
     9001 agtctcaaag aaattatgac aataataaga ttctttatga acaggaagtc attagtttag
     9061 accaatttaa aaaaatagaa ttttctttag agcaaacaaa acaacagtta gattctgctc
     9121 aaagagcata cgatacagca acttcaaaaa gtatacctca agctaaagca cttgctaaaa
     9181 aacagcttga ccaagctcaa gtatcatata atttagcaat gagtaattta gacaaattaa
     9241 cattaacatc tccagtagat ggtacaataa cagctaaaaa ctttgattca aaggaaatga
     9301 taacacaatc acaaccagct tttattattt ctaatcctaa tatactagaa gttgatttaa
     9361 atgtagcaga atcagatata ggtaaattta agaaagatgg aaatgtagat gttataattg
     9421 aagaccaaag gattttagga aaaatagatt atgtaccttc agtagttgac cctcagacat
     9481 ctttatatcc tgttaaagta cttgtaaata atacaaacaa caaatttaag gcaggtatgt
     9541 ctgctcaagt aaacttaagt gttgaaaaag aaaatggtgc tgttacagta cctaaaaaag
     9601 caatatttga agaaaatggt aaaaaatatg tatacatagc aacaaaagac aatatagcaa
     9661 agaaacactt ggttcaaact ggaattgtaa cagaggataa aatagaaatt aaaagtggtg
     9721 taagtgataa agatacagtg attatcggag ggataagtct tatttctgac ggaactaaga
     9781 tatttcctgt agaaaaggag aagtagacta tgaatttaac acagacttcc gttaaacgtc
     9841 ctctcacaat cataatggtc tttttagtat taatagtttt tggtggtatt ggatataaaa
     9901 aaatgtcaat aaatctaatg cctgatatag aaataccagt tgtaatggtc atgactactt
     9961 ggacaggtgc tggtcctcaa gacgttgatg aacaagttag tcaaaaagtt gatgaaagtt
    10021 tatctgccgt ttcaaatgta aaatctacta tatcaagttc acaagaaagt gtttctatgg
    10081 tagttgctca gtttgaattt ggaactaatt tggatgaaat aatgaatgat gttaggtcta
    10141 aagttgatgc attacagacc agcctcccag atgatgcagc taaaccaaca gttttaaagc
    10201 tggatatgaa tgcacaggct ataggtcaac ttgtcatatc tggaggaaat gaaaatagtt
    10261 cacaagcctt aagaaaatac gctgaagatg taattcagcc taaaatagaa tccatagatg
    10321 gtgttacttc agcagacctt aaaggtggag aaaaagcaca ggttaatgta atagctgacc
    10381 cagctgttct ttcaaattat ggagttagtt tatccactat aaaaggtgtc ttatcctcta
    10441 gtaataaaac attcccttat ggttcaatta ctcaaggtga ggataaaata gttttaagag
    10501 cgattgataa attagaatcc ctagatgata taaaacagat tcaaattcct gtaaaaggag
    10561 gaaatacagt tagattagat aatctttgta gtgtagatta tggatatgca gacaaagata
    10621 gtatttatag atacaatgga aaagacagtt tggtaataga tatttctaaa caacaagatg
    10681 ccaacactgt aaaagttatg cagagtgcat acaaatacgt agatgaattg aataaggaaa
    10741 atcctcaatt taaaattaaa attgctaatg atacaagttc atacataagt gaatcaataa
    10801 acagtgtaat gagcaacttg cttataagtg ctgttatcgc atttattgta atatttgctt
    10861 tcctaaaaag tgtaagagct tcactagttg ttgcagttgc aataccaatt tctataatag
    10921 gtgctatagc aattctctac tttactggtg aaagtttaaa tcttattact gcaagttcat
    10981 tggtaatttc agttggtatg gttgttgata atgctacagt tgtaattgaa aatatattta
    11041 aatataggaa aagtggcaga ttgagtcttg atgattgtgc tattgaggga acaagaactg
    11101 taacaaatgc aatacttgca tcaacattga ccacaatagc aatattctta cctatcatgt
    11161 ttacagaagg tatagctaaa ataacttttg gggcattagg taaaacacta atagcttcac
    11221 tagcattctc ctttataggt gcaattacac tcgttcctag tgtatttgca aaattaagca
    11281 gaggaaaaaa tagtcaaaag atgcaagaaa aagatagtcc tatatttgat aaggtaagtg
    11341 aagcatataa aaaattatta agtgtatgtt tgagacatca acgcttagtt gtaatatcaa
    11401 gtttacttat ttttgtagct tccttatttg gaatgggatt tataggaatg gactttatgc
    11461 ctgcagcaga caagggtgaa ttatctattt ctatagaact tccaaaaggt cttagcctag
    11521 aatccaatga ttactatgta tctatgactg agaaaaaagt ctcagatatt ccagaaatta
    11581 aaactttaat aacaactttg acatcagatt caaataatag taaagcaagt atagcaattg
    11641 aattagaatc tcaaaaaaat agaaaaagaa ctactgatga aatagaaaaa gagataattg
    11701 atagagtggc tactgtacca gattgtaaaa taaatgtaag tcaaaacagt agtgttatgg
    11761 gtggagctgg aggagcagac ttcacattag aaatgaaagg tcctgattta gatgtattaa
    11821 aaatactggg aaaagaagct gaaaaagaat ttagctctat aaaaggattt agaaatgttg
    11881 aaacttctct tacagataca acacaagaag ctcaatttac tatagataaa cataaggctc
    11941 aagaatatgg tgtaaatact gctgaaattg caggcatgtt acgtacagca ataaatggtg
    12001 actctgtaac cactgctact attgatgatt acaaagtgga tgtaaaccta aaatttaaag
    12061 cagatactat tgatagctta gaagatataa agcaactaaa agtaaactct gcaactggaa
    12121 aagaagttcc tcttggtgct ttttcagata taaaaatggc agatggtcta caatctatat
    12181 ctaggactga tggagatttt tctgtaaata taactgctac acttgacaat ttagatgctg
    12241 gtactgctac aaaactagca ctagaaaaaa cgaataaaat ggtaattcct aaagattact
    12301 ctataggtgt tggtggtgaa acagaaatga tgaatgaatc tatggcaagt cttggatttt
    12361 caatggtcat agctatagca ttagtttata tggtaatggt agctcagttt gaatcattta
    12421 gtaaaccatt tataatcatg ttctgtgttc catttgcatt cgttggagtt gtgctttcgc
    12481 ttctagttag tggtcaaagt ttaagtactg tcggtatgct aggtataatc ttacttatcg
    12541 gtattgttgt taataatggt atagttctta ttgactacat agagcaactt agaaaaacaa
    12601 atcgtaacaa tgatttaatt ggtttggttt caattggttg tgcagcaaga ttaagaccag
    12661 tcttaatgac tacagcaaca acaattttag gtatgttgcc aacagcacta tctcttggtg
    12721 aaggtggaga aactatgcaa ccactagcca tagttataat gggtggtcta actgtatcta
    12781 cacttataac tttggtgctt atacctacta tatacttaat atttgataaa tgggaaaata
    12841 agttttcaga caaaatgcct aaaatatttg gtaagataac agataaaata ggaagtataa
    12901 aacgtaaaat aataaagaaa ccaaaattga aagctaaagt ttaaatagaa tggagggtga
    12961 ttgtattgaa taaaaaaatg agcaaaatag ttgcaattgg ctgtggtgtt ggtataataa
    13021 ctgccaattt aatcccagtt tacgcagata ataatacttc ttctataaac aaagttgata
    13081 attctatttt aagtgactca aataaaagaa catctgaaaa ggaaattttg actgctagag
    13141 aagctgttag tgctgcactt aaaaatagtg aaaaattaaa aatgaaatca gaagaaataa
    13201 aaatgttaaa agaaaagtta gaagtacaag atgagtttga tagttttact ggaagtgaca
    13261 actcgtttcc atacgaccaa attggacttc ttaaaaatca aagtgaacag gctaaaggct
    13321 ttatggagga ccaaatagca aatgatatta ctaataaatt taacgattta gtttcaagag
    13381 aaaatgagct agataagata aaaaacaatc ttgaaataaa aactaaagaa attaaagata
    13441 tgaaattaaa aaaagattta gggttagtaa catctttaga aactgaatca gctgaacttg
    13501 aacttcaaac actacaaaat actcaaaaag ctaaacttca agaactaaaa aacaatcaag
    13561 actattttaa gttattgact aatatagatt taaataatta tcaattggat aaagaatata
    13621 gatttgaatc ttttagagta ggtggctcag ttgattcata tatggaaggt aaggttaatg
    13681 aatatttaaa atacgaccaa ttgattttag aacgtacaga agaaagcttt aatgataaag
    13741 atgagaacaa agcagattta ccagatagac ctaaccttac aagaccagtt gctcctacaa
    13801 aaccagagca aggtaaccta actgatgatg aatacaaggt tcttatggat aagtatgaaa
    13861 aagattatga tagatataaa aaagaagttg aagcatacaa tcttgaaaga cagacttatg
    13921 ctgctggtct tactacttat gcaaattatc ttcaacaaaa atttaatact gaaaatggtc
    13981 tagtaacatt agaagacagt aaaaaagctc ttaaaaaagg gttaattgat agctatgctc
    14041 aattacttgc tttagaagat acaattcaga ttactaaaaa acaacttgat ttatcagaaa
    14101 aacaattaaa aaatactaaa ttaagatatg atttaggatt aattactcta actgattata
    14161 aaaaacaagt ggtaagtaat gaagatgcta aaaatagcta tgactctctt attgtgaatt
    14221 ataactcact aaaaaatggt atagaaaaac cttggatact taatactgga aaataattct
    14281 ggtaaataga aagattactt taacatacgt ttgattaaaa aatagttatg cacactcgtg
    14341 gctttagtca tggaatattc agaaggcaaa taatagaaat agattagtaa aaatatattt
    14401 acttataaaa ctgtatactt ttatagaggc tatctcaaaa tagagataag cctctttttt
    14461 attgtttaaa ttataaaaat atatttgatt ccatacaaaa agagtgcctt atgaactaaa
    14521 aagttcattt tgagacaccc tcaaaagctt aactctaaat ttaattattt tttatcaaat
    14581 gtctcatcta ttttacatct caccatgtta acaaattcag aaatattata tcctctaagt
    14641 ttgcatccac atttaggaca ataatccagt ttcctagata ccaaagccct acaactaggt
    14701 tctggacatc ttatttttag actctcatct gctactttaa atccacatcg tgggcatata
    14761 ctacctggac gtgatgatac ttcctttcca catttaggac actttgtcaa ctttatcccc
    14821 tccagtaaac tcaatttaat tgatagttga aatttctctc tacaataata tatgcaatat
    14881 aattaaatac gtttcactta caactatata agttaaattt ttataataaa aatcccctat
    14941 attcaattta caaatactta atttgataca ttgaacaata ggggatttta tttttattta
    15001 gttacatatt ttgcagtcta ttattatcta ggatttttta tagatgcttg agctgctgca
    15061 agtctagcaa ttggcactct aaatggtgaa caagatacat agttaagtcc tacactataa
    15121 cagaactcta ctgaagatgg ttctcctcca tgctctccac atattcctag ttttaattct
    15181 ggtttaactt ctctacctaa tttagctccc atcttaacta acttaccaac accattttgg
    15241 tctagtactt ggaatgggtc tttttctaat atttcttcat ctacatattg acctaagaat
    15301 ttaccagcat catctcttga atatccaaat gccatttgag ttaagtcatt agtaccaaaa
    15361 ctgaagaagt ctgcttcttg tgctatttca tcagcagtta aacaagctct aggtatttct
    15421 atcatagtac ctacagtata aggaacttct ataccttctt cttttattat agcgtcaaca
    15481 gtttctacta tcatttttct tattattttt aactcattta cttctccaac taatggaacc
    15541 attatctctg gagaaacttt aacacctgct ttgattgctt ctatagcacc ttgtattata
    15601 gctttagatt gcattacaca tatttcagga taagttattg caagtctaca acctctgtgt
    15661 ccaagcattg ggttaaactc atctaaatca actattctct tcttaatatc acttactttt
    15721 attcccatag attttgaaag ttcttctata gtctcatcat catgaggcaa aaattcatgt
    15781 agtggtgggt ctagtaatct tatattaact ggttttccat ccataacttt aaataactct
    15841 acaaaatcct ctctttgcat tggtaatatt ttttcaagag ctttttctct ttgttctact
    15901 gtattagata atatcatttc tctaactgct ggcaatctag cttcatcaaa gaacatatgc
    15961 tcagttctac atagacctat accttctgca ccaaactcta tagctgcacg agcatctcta
    16021 ggattatctg cattagttct aaccatcata catttgtgtt tgtctaccca gttcattaat
    16081 ttttcaaaat ttccagttaa agatacttct gttttcttaa catctcctag gtacacattt
    16141 cctgtagaac catctataga aatgtattct ccttctttta taactacatc atcaagtgct
    16201 cttatttctt tattaaactc atcaactttt atttctccac atccagcaac acaacattta
    16261 cccatacctc tagcaacaac tgctgcatgt gatgtcattc cacctctagc tgtaaggatt
    16321 ccttctgctt taaccattcc ttctatatct tctggagatg tctctagtct aactaaaact
    16381 actttttctc ctttttcatt tgcttttact acatcatcag cattgaaata aactttacca
    16441 cttgctgcac ctggtgatgc tggtaaacct tttgctataa ccttagcttc ttttaatgcc
    16501 ttatcttcaa atttgggatg taataattgg tctaattgat taggctcaat tctcatgata
    16561 gcttcttttt catcaattat tccagcttca actaaatcaa ccgctacatt tattgctgct
    16621 gctgctgttc tcttaccatt tctagtttgt agtatatata atctttcatt ttctatagta
    16681 aactctatat cttgcatatc tttataatga ccttcaagta tatgagtaat ttttacaaat
    16741 tcatcgaata cagctggcat tacatctgca agagttgata tattttgagg agttcttata
    16801 cctgcaacaa cgtcttcacc ttgtgcattc attaaaaatt caccaaataa tttattttct
    16861 cctgtagctg gatttctagt aaatgcaaca cctgtaccac tagtttctcc catattacca
    16921 aataccattg attgaatatt tactgctgtt cctaagttat gagctatatc attcaattta
    16981 cggtatacga ttgcacgagg attattccat gatctaaata cagcctctat tgcaagcatt
    17041 aattgctctt ttgggtcttg tgggaaatca ttttttattt cttttttata aattgcttta
    17101 aattctttta ctatttcttt taaatcatca gttgtaagtt ctgtatcaac tgtgtatccc
    17161 tttgcttctt ttactctgtc taatacgttt tcaaatttat attttggaac ttccatagca
    17221 acatcagaaa acatttgtat gaatcttctg taactatcat atgcaaatct ttcattttgt
    17281 gtagcctctg ctaagccaac aacactattg tcattaagac ctaggttaag aattgtatcc
    17341 atcattcctg gcatagagaa tactgcacca gaacgaactg atactaataa tggattctta
    17401 ttgcatccta atgttttatt taaatctttt tctaaagtag ctaaatgctc ttctatttct
    17461 tttattatct ctgctcttat actttcattg ttaacataat aatcattaca cgcttctgtt
    17521 gttatagtga atccaggagg gacaggtaag cctatcttag tcatttctgc taaattggca
    17581 cctttacctc ctagtaaaga tttcatgtct ttgcttcctt caccaaaact ataaacatac
    17641 ttagtttcca ttgttaaatc ccccattaat ctttttattt taatttatat catttttatt
    17701 aatagacatt attaaatttc tatttctttg tatatcttta gaccattttc tttcattatg
    17761 tctaaaatta tacctgctgt ttcttctatt gccttatttg aaacgtttat tactgggcat
    17821 ccaattcttt tcattatctc ttctgaataa tctaactcct gaagtattct ttctaaatta
    17881 gcgtagtttg ctttactgga caatcctaaa gcttttaatc tttgggttct tatctcattc
    17941 agcttttcag gtgaattagt aagacctatt atctttttag tatctatctc aaacacttct
    18001 ttaggaattg gtatttctgg aactaatgga acattagcta cttttatatt tttattagct
    18061 aaatacatac tcaaaggagt tttagatgtt cttgatattc ccactaaaat tatgtctgct
    18121 tgaagaacac ctctagggtc tttcccatca tcatatttca ctgcaaattc tatagcttca
    18181 actctcttaa agtaagattc atctaatttt ctaattatac cagcttctct tttaggtttt
    18241 cttcctgttc tcttgcttat ttctcttagt atatctgtca ttaaatctat acaactaaga
    18301 ccttctcttt cgcaatatct ttcaacaata ctgcataatt cttcatcaac taatgtatat
    18361 acaattaaag cgttttcagc ttttgcattc tccaaagttt caagtagtac tcctttatta
    18421 atcatgtatg gaaatctttt tatttcataa gtttcattca cataaaactg agacatacat
    18481 gcctttgcaa cttgttgtgc agtctcccct actgaatctg atactgcata tataattagg
    18541 tttttcacca gcatacctcc ttaattgtca actatttcta agaatagctt agttatgttg
    18601 gtttttgata ttctcccaac aactctcata tgatttttgt cttctccctt atattcaaca
    18661 atcggaatcg aatctacttc atgttctatt atttttcttg aagctaataa aacacttgct
    18721 cctttagtta aagtgactac atttggagtt cttgtcatta tcatacctat tggcatttta
    18781 tttatatcag aacctcctat agttgctttt agcaagtctt ttctggaaac aactccacat
    18841 aactcttcat tctcatctat aataactata ctccctacat cagataaaaa catagtgact
    18901 attacatcat atatactttc atccttctta gctagtacag gcatgctcat tatatcctct
    18961 actgtttttt cttttacact tttaccaatt aaatttattt cactaactcc tgaataaaaa
    19021 tatccaactt ttggccttgc gtctaatatt cctgtcattg ttaatatagc taaatcagat
    19081 ctaagtgtag cacgagtcac attcaagctg gaggcaatac tttcactcgt tattggttca
    19141 ttttccttaa ctatatctat aatttttagt tgtctttcat taagctgaat aataatcacc
    19201 ttctttcatt gtgctatact ttttatcttt tcgcatctta tatagtatat tatataacta
    19261 tatataccat tctgtaaaca gattttttat tgaatacgat atatttttta ctaagttctc
    19321 tcgcttaaag atatttatta tatattaatg ggggatattt ctttaattaa tagaactata
    19381 ttagtattac agttaatatt ataatacata attggtcatt ttaattcatt ttatattaaa
    19441 atttttaata atattgtttc aatgtgaata taaaattgca gaactaattc aaaataattt
    19501 ttacgactac aaataaccta taatatactt ttaaagaaag tatcctaaca agaatatata
    19561 aaaatttaaa agggttgatt taaaaataac catcaaccct ttttactaat atctatttat
    19621 attaccatca aatcttaccc aaatattttt tcttgcaatt gtcttaaatg atataaagta
    19681 gtatcttttt ctatctctac catatcgtaa gttataactt cacctttttt aatatctttt
    19741 acaactttag tctttttact tatcaaacca ataggtacag cattcatagc ctttgctaca
    19801 tcgtattttt ctatagtacc atagcatgta tatgctccat agccatccat aaactcacct
    19861 tttttcaaat ctttcttagc tatagtcata acttctgcta ctagtccagc tttaggtact
    19921 attgtagcct tatggtctaa aactgccata gctgctgata aaggagtctc taaactacat
    19981 aaatgatatg gtctatataa tatgtaatta ggtccatcac ccatacttaa atattttagt
    20041 tcatcattaa ctgcttttaa tttatgggca actactacga aaactccagg tgctatacca
    20101 tttacaaaat caactacacc ataattatct aatactccac cttcgctttt taatgcatat
    20161 ttcttaggta cttcattaac tgtagcttca ataccatgac cacctcttac atcaggcaca
    20221 aatccagttg cattacacat taaagccatt tctaccattg ttttagttcc ttctttaaaa
    20281 gaagctatca tatgaggtga agctcctttt ctttctgctt cttctctaac tgtatcagga
    20341 ttacaatcta aatctaattt attattttta cctttaccta tcactctaac ttcaaacccc
    20401 attgcatctg caaaatcaaa taattccatt actgcacctg gctcatctcc tgcagaacct
    20461 gtaaatatta ctccagcatc atctgctaat tttttaagta ttggtccaac aacacaatca
    20521 gtttcagcat ttaacataac tatatgtttt ttatttaaaa tagagtttaa tgctatctct
    20581 gcaccaattg caataccccc agttgcatct ataactacat ctattgactt agttttacaa
    20641 gccacaagaa agtcattaca tgtcaatact tttccttctt gtaattttat ttctgcatcc
    20701 ttttcatttg ttacattatc tataatttct tcatctattc ctgcatcagt aaaagcttta
    20761 tgagccaact ccaaatttat atctacaaca atagaagctt caataccttt catatttgcc
    20821 atttggctta ccattccatt tcccatatgc ccagctccta taagagctac ttttattttt
    20881 ttaccttcct cttccaattt tgcaagtttt ctgtttaaat ctaacatacc aattcctcct
    20941 gttataataa ttttattttc aaattaagaa atagttatta aatctccaat agttatatct
    21001 ggatttccta tttccacatg tatttctcct ggtaaattta cttcacattt tccatcaaat
    21061 ttgattgtac aatgcccaat ttctctaaga gtcttctgag caatatcacc aactgaaact
    21121 atacaataat ctctattccc tatagtaagt gtatctccta tttcaacatc actttttaat
    21181 gttgctattg aatgaattac agatatatcc tttaagtcgt catcattaat ggtttcatca
    21241 tatataataa gacaattgct ttcatccatt aactctttaa ctaaactgcc tatcccactt
    21301 atcttaactt catatttcat gacattcctc ctgataattt atatttatat tgagttaatt
    21361 aaaagaaaca tttatttttt cttttataaa ttttatagct tgtacaatac tctcttcatc
    21421 tttaaatttt tgctctgcac tatatatatc taatccttct atttcttcaa tctctttaaa
    21481 tttagccatt actgtacgcc cttttaaaat ttctccaaac tttataaacc catctgaatc
    21541 tgaagatata atggctatac ttcctttaga aaaatagctt ttctttttgc ctgtagacac
    21601 tatatcaccc ttttttttag ctctatttaa agttttaaaa tacaatttat tctgcttcat
    21661 tataaatata gtatttaaaa tataagcaac aaataaaatt actaataatt tcatatttat
    21721 acaccttcca aaaatcacat tatttttaaa tctgtataac aactataaat gctgtacaat
    21781 agttatataa ggtttttaag taacaccttt ttaaattcta aaaaagttct acatttactt
    21841 atcttattcg ttaattttac atcttggcct atctttaaaa cttcttcata aatttttact
    21901 aataagtctg agtctatctt attctcacat ggaaacattg tcataagaat tatttttata
    21961 cttctatttg catattctat tggttcttct aaaattccaa ctgccattaa aaacttatct
    22021 gatttttcat ttatagaatg aggaaataat aaacctttat caaatactgt gggagatttt
    22081 tcttctctat tgactatatt ttttctaaac ttctcatcaa tacatcccaa atccataaga
    22141 tggtccatca ttttttctaa tgaggcaagt atagtctttt catttaatat cataaattta
    22201 tcttcatcta acaaattatt tattagtaaa tttgtagaat tagtagtgtc aatattccct
    22261 tctcttaggc acaatactgt ttttaattgt tctcttagtt tgttttcatc aaatattgta
    22321 tttattttta atactattgt atttatattt gatgtgtcta aatcaatagt cgtaaaaact
    22381 atatcgtatt catctaagtt aatatttctc aaattaaaac ttgaaagagt atcaatttta
    22441 ggattatttc ctatcagttt ttctactctt attttcaata gttttgctgt tcctagacct
    22501 gtactacata taattgctat tttttttatt gaatagaatc tactgctatt tctttctaaa
    22561 tatccactga aatggattgc tatatatcca atctcatctt ctgaaacttc taagttatac
    22621 tttttctcta ttacttttcc tgctatttgt gctaatttaa atggaagtat acaattttgc
    22681 ttaatctctt ctaacaaaac attttttaac tttatattaa ataatagcct gtttaaagta
    22741 aaactaagat gatatcctag acctactctt aattcatcct catttataaa aatacccata
    22801 tcgacatata tttgattaaa tatattttcc atcaactcat caatgttttt actaattcta
    22861 ctactattta aagcacattc tgatgctggt gcatttccac taactaacgg tatagttaaa
    22921 taaataattt cttcatcatt taaagtacat tcaaacattc ctgatattat atgttttatt
    22981 tccctagcaa taaagtattc atcatatgat ttaagtaaat caaactttac atcataatct
    23041 tttactttct tttcttcttt tactctatag actaaaacta ctatgtagtt aataacttct
    23101 cttaacattt catctgtaac ataaaaatta ttttttttaa ataaagtcaa tagtttttct
    23161 tctaaattta tgatttcttc ttttttgatt cctttaaaat actttgaatt acttaaatct
    23221 tttcttgagt ttttatacaa ctgatttaat ataaacagtc taatatcaag ttcatttcca
    23281 tttaatttca tacctgtatt ctgtttttta atcaagttta aattatatga agccaaaact
    23341 ttttctacat actggaaatc atttactaaa gtagttcttc ctacacacat ctcatcagct
    23401 aaactatcaa gtgtaataaa tccatctagt tctatcaagt aatttagtat aaactctact
    23461 ctatcttctt ttgaatttaa tgaaaataca ttttttctat tcatatcaat aatcttattg
    23521 agtatctgct catcttttat ttctagttta tagccttgac cctttatata tttgattact
    23581 gctatatcat tacctaaatc tttattcaat tgttttatat acgtccttac acttctagtt
    23641 gtgacattca attcatttgc tattgagtta atactcacaa actctttttt actacacata
    23701 atcaatatct taaatatctt gcggtcaata gaaggaattt tctcagttac actcattttg
    23761 tatctcctcc ttgatttcat tctagtacaa atttgaaacc aaattaatac ataaaatttc
    23821 actttaataa aggaaaattt agtattaatc taactcgata attacagcta attaatagta
    23881 taaaagctag tctttcatta acaaaaaatc ttgactagct taaatttata tttacaattt
    23941 tattaattaa ttccaagcct tatattgaca ttaaatatta tctcaatgca aatactgcaa
    24001 ctccatatgc aataataaca gctattggac cagttattaa acgagagtaa aataaagctg
    24061 gaacaccata ctctacagtt tctggttctg cttctcccaa acttaatcct actggtacaa
    24121 aatcacatcc agcttgccca tttattgcaa ataaagctgg aagtgctaaa tatgctggta
    24181 ttgcaccaag accaatttgt gtacctacaa gagtccctac tacttgagct ataactgcac
    24241 caggtcctag tattggtgat aagaatggaa gtgtgcaaat tactgatata atcaataatc
    24301 caccaatatt acctgcaagt ggagatataa ctcttgcaat ccagtctccc agtccagatg
    24361 ctaaaataat tcccataagc atacttacaa atgccataaa tggtattacg ttattcatta
    24421 ccatttggat agtatctcga cctgcatcat aaaattttga tactacttgc cctgcccctt
    24481 gaccaataga aagtattatg ttctttttag catattcacc ttgtgctttt gacttaacct
    24541 catcataatt atcaggcttt ctaatagaac tcttattttc gcttttattt tcttgagatt
    24601 tttgtggcat atcttcccca tctacaacac ttatacagtt aggattaaca tctgatacat
    24661 aatattcttc tgttataaat tttgctaaag gacctgtttt tccaactgga tttacattta
    24721 ttgtaggtat ttttttcttt ggataaactc cacatctagc agttccacca caatcaataa
    24781 taactactgc tacttcttca tcagaaactc cagttttaaa tccatctaca atttcacaac
    24841 ccagtagttc ttttattttt aatgttactt catggatacc gccagcagtc attgatagta
    24901 tcttatttct attcccttct ttttttatat acaaaggacc tccccagcct gaagttccct
    24961 tttctatttt taatatttta ttctcctcca ttttatctac ctcctaagcc ttatttgttg
    25021 ctctattttt tcttgttaga aaagcataca ttttttctgt tactatacct cttataaaaa
    25081 ttacaattag accaactata aaataccaca atgccagtgt agtagtttct ttacctaaag
    25141 tagtcaaacc tgctgatatt cccaaccata caaaaagttc tcctgcattt gcatgtggaa
    25201 aaagacctgt aattggatgt acaaatgaaa ctgctgcatc ataaaatcct gctttgtgct
    25261 cttcttttaa aaatctacca aatgtatagc acataggatt tcccaagaaa aatactgata
    25321 ctaatggaag tagaatatat cttgtaaaag agttctttcc tagcttagaa gcccaattat
    25381 taactctttc ctcaccaatt atcttaatca aagagttaat agctaccatt aatacaatta
    25441 gcgttggaag agtacctgaa acaagaccta taaattgttc tccccctttc tgaaacaaac
    25501 cgataaacca ctctgcacct ttacttagac ctgtaataac gttttccata aaattataac
    25561 ctccctataa tatctttaaa tttttaattt tactgcttac cataaatttt acaaattaca
    25621 tcttttttct gtactatatg ctaatattgt aaatgttttt ttattaatat cattttaata
    25681 taatattttt gataaataaa tacatctttt ttcaatttta taaaggaaaa aattgtacta
    25741 at
//
LOCUS       DAMKNB010000049        25682 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.051, whole genome shotgun sequence.
ACCESSION   DAMKNB010000049 DAMKNB010000000
VERSION     DAMKNB010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 25682)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25682)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25682
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.051"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            complement(1..2493)
                     /locus_tag="PC494_002294"
     CDS             complement(1..2493)
                     /locus_tag="PC494_002294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDF3912790.1"
                     /translation="MNHNTSIKNKDSNPKIFLVLTLYLLGIFMGAIDTGIVSPARTII
                     QNSLGVNEKTGIWMITIYTLTYASVIPISGKLADKIGRKYVYLVSIFLFGSGSLICGL
                     SSLFSNFYILLIGRVIQAIGGGGIMPIATAEFGTTFPENKRGMALGLVGATYGIANIL
                     GSSIGSTILSIFGTQNWKWLFFVNLPICLIILIGGVFCIKNNKSESKEKIDKLGTLML
                     ICIIVSLLYGLMNIDFFNFKNSIQDISVYPYLLTFIVLIPIFIFIENRAKDPILSFEY
                     FLNPRILIVLILSLIVGIGMMGMVFVPQYAENALKINAGSGGYFVAILGLFAGIAAPL
                     SGRLIDKFGAKKILLLGFSVSMIGSLYLVLIALKTNTVFSVCVSLIFMGLGMGFTMGT
                     PLNYMMLSNTRLEESNSALATLSLIRSIGTSISPAIMIGFIAHAGLSVQDNIMDLVGK
                     PSTPKIVQLEELENMIDDLKSDPEMAKNLKNVSIPNMNDTSNINMDMTGGKLPKSLLN
                     KVQSADTTNITNITKEISTTMFDEKVPSIITKIQKNVQKGIDGTQSGINGIEDGENKL
                     NSGIKGVQTGIDNMVKARAGINQGIDGVKKGIAGVDKGIKGMEQGLEKQDEAIKELTT
                     AYNKIPTTEKTPTDNENNSNEQNQSNTSNSESDDTKNDSTENKNNNSSENKPNVNEQK
                     ESLNAQIQQLKKTRDDLNTKLQKNKTQKNELSKKLRSMESQKKELQSKLNNSISQKKD
                     MEKSLDTMQQQKKSLQAVLAKTQEVKTEIPKAFDKSKLDYINSIENNRTKIENTLQST
                     LNSGFKQMYITVFCVNLLAFIILLFYKENKTR"
     gene            complement(2507..3049)
                     /locus_tag="PC494_002295"
     CDS             complement(2507..3049)
                     /locus_tag="PC494_002295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDF3912791.1"
                     /translation="MPKILENVKEDILKVSRDMILEEDYSNISIRKIAQRCGISAGTV
                     YNYFNSKQEIIEYITKSEWDLLIRRIEYSNKNTEDYIKKLNIIFTEIRNFINKVHNIQ
                     YNDFLNTFETERFFEMKKHKDDFHEQLSNKVYEALEKESFFNNDKLVCNIIIKMFFSY
                     STYLHIEFEDLKPYIEKLIH"
     gene            3293..4807
                     /gene="glpK"
                     /locus_tag="PC494_002296"
     CDS             3293..4807
                     /gene="glpK"
                     /locus_tag="PC494_002296"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HDF3912792.1"
                     /translation="MEKKYVMALDQGTTSSRAILFNKKGEIVKIAQKEFNQIYPKAGW
                     VEHDPMEIWGSQSGVMREVIETAGIRPEEIASIGITNQRETTVVWSRYTGKPIYNAIV
                     WQCRRTSEICDELKNKGLEESIKEKTGLLIDAYFSATKVKWILDNVEGAREKAEQGEL
                     LFGTIDTWLIWNLTRGKVHVTDYSNASRTMMYNINDLEWDEDILRELDIPISMLPLVK
                     PSSYVYGHTDERMLSGAKIPIAGCAGDQQAALFGQNCVEEGTAKNTYGTGCFLLMNTG
                     SNIVKSKHGLLTTIAWGVDGKVTYALEGSIFIGGASVQWLRDELKIIESAKDSEMYAN
                     RVEDTNGVYVVPAFTGLGAPYWDMYARGSILGLTRGAKKEHIVRATLESIAYQTKDVL
                     EAMQNDSKLKLKSLKVDGGASNNNFLMQFQSDILNVDIDRPKIVETTALGAAYLAGLS
                     VGFYIGRNEITSKWSVEKEFNPNMSEEKRCKLYKGWKKAVSRALSWEKEDELDI"
     gene            complement(4921..5550)
                     /locus_tag="PC494_002297"
     CDS             complement(4921..5550)
                     /locus_tag="PC494_002297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDF3912793.1"
                     /translation="MDKNYTMPIYQKIALDIANKIYTGEIQEDSVLFGRSVLAGKYNV
                     SPETIRRAVKILEDIGVVKSIKGKGVIVLSPDKASSFIKKYRDITNISSYKSTLYNLI
                     DTKSNLENEILDTINKILDYSNRLEIINPLVPVQFTINSNCKYIGQTAAQTKFWQNTG
                     ATIVAIKRGEELIISPGPYIEFLEGDILLVVGDQHIYNSIPMFLYENEK"
     gene            6138..6929
                     /locus_tag="PC494_002298"
     CDS             6138..6929
                     /locus_tag="PC494_002298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LamB/YcsF family protein"
                     /protein_id="HDF3912794.1"
                     /translation="MYKVDLNSDLGESFGTYKIGLDEEVLKYISSANIACGFHAGDPS
                     HMEKTVQLAKKNGVKIGAHPGFLDLIGFGRREMKITKQEAKDYTKYQLGALMAFASSN
                     GCNIQHVKPHGALYNMAAKDKELAMGICEAIYEVDKDIILLGLYNSEMINSAKEIGLR
                     FANEVFADRAYDNNGFLVPRNVEGAVIHDTKHAIDRVVRMVKEGTVETLTGEVIHIKA
                     DSICVHGDNPKAIEFVKEIRKRFELEGIEVCPLENIEVCSSENIV"
     gene            6958..8178
                     /locus_tag="PC494_002299"
     CDS             6958..8178
                     /locus_tag="PC494_002299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="divalent metal cation transporter"
                     /protein_id="HDF3912795.1"
                     /translation="MSTKNITDKTKNKKDVGALIGAAFIMATSAIGPGFLTQTAQFTQ
                     DFGPNFSFVILITTILFIGAQVNVWRVIGVSGLRGQDIANKIIPGLGYLVAFLVALGG
                     LAFNIGNVGGAALGMNVMFNMNMTLGTVLSGLIAIFVFMSKNSNSLVDKITKFLALGM
                     IIIVGYVAISNHPPVGEAVSRMVKPENPKGLIFPIITLLGGSVGGYITFAGGHRLIDG
                     GITGEENIKEITKSSLLGILVATMMRVLLFLAILAVVSKGLQLDPENPAASAFKFSAG
                     AIGYKFFGLVLWSAAITSVIGAAYTSVSFLKTLNPFIDKYEKYFIIAFIAISTLIMAF
                     IGKPATLLILAGALNGLILPITLGIMLIASKRKDIVGDYKHPTWLLIFGLIVVLISAY
                     TGITSLSSLGALFA"
     gene            8198..8893
                     /gene="pxpB"
                     /locus_tag="PC494_002300"
     CDS             8198..8893
                     /gene="pxpB"
                     /locus_tag="PC494_002300"
                     /EC_number="3.5.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-oxoprolinase subunit PxpB"
                     /protein_id="HDF3912796.1"
                     /translation="METRYLISGDKAVVAEFGNEISEDINKKVISFMRAIEISNLKGI
                     VTEMVPTYRSLMISYNPLEIDFDSLIENLKKIEDNLESIVLPKPKIHEIPVCYDEVFG
                     IDIKNVASYNNLTVDEVIKIHTSREYLIYMLGFTPGFPYLGGMDERIATPRLEVPRTK
                     IYGGSVGIAGSQTGVYPIDSPGGWQIIGRTPLKLYDENREEQILLRAGDFIKFVPITL
                     DEFIEIEKNNLSI"
     gene            8923..9909
                     /locus_tag="PC494_002301"
     CDS             8923..9909
                     /locus_tag="PC494_002301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin-dependent carboxyltransferase"
                     /protein_id="HDF3912797.1"
                     /translation="MGFKVELGGFQTLIQDRGRVGYGQYGVSGCGAMDEYAHRVGNIL
                     VGNSEDEASLEVLMLGPTITFDEYTQIAVTGGDLGAKINGKEIQNWRSYQINPGDVLS
                     FRGVKSGARAYVSIAGGIDVPLAMGSKSTYTRAKIGGFEGRALKKGDYINTFIQEKDF
                     TINKKLSSKYIPTYSSEIVLRIVKGPQFDAFSNGEVEKFLSNKYKVTNEIDRMGCRLD
                     GESIKHLNGADIISDGISYGAIQVPGHGKPIIMLSDRQTSGGYTKIGNVISVDLYKLA
                     QAKPNDVVKFELVDIYEAHRLLREQEDKIQDIYKSMKNIRVVKAKVLNDIAV"
     gene            complement(10104..10670)
                     /locus_tag="PC494_002302"
     CDS             complement(10104..10670)
                     /locus_tag="PC494_002302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF3912798.1"
                     /translation="MLGEKMRNIRKSKKKTLSDVSKLTDLSISYISQIERDAIEPSLS
                     SLRKIAEVLDTPLYMFMDDNNTDDLVIRKEDRVMMKFPKSEMFYEIVSPMPTTEFTPS
                     ILFVEFELKPESEDAKDYIYHASEEIMVVTSGVVDICMGEKVVRLNPGDSTFIKANVP
                     HKIINPSKDTIARGYGVISPPIWPIKSK"
     gene            11022..12089
                     /locus_tag="PC494_002303"
     CDS             11022..12089
                     /locus_tag="PC494_002303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptide epimerase"
                     /protein_id="HDF3912799.1"
                     /translation="MKITDIKFEKLRIKLKKPVVVSFGVIEYGESIILKIETDEGYCG
                     FGEAAPLAAVTGEVLDNVLSVLLMFKKELIGKDPLDIETIHTIMDGIIIGNTSAKAAI
                     DIALYDIKGKIMNAPLYKVLGGFDSKVQTDITISIDKPEKMAVEALERVKEGFRILKL
                     KAGINPEDDIEAVKLIREAVGESIRIRIDANQGWNVNSSINTIKKLEEFNVDAIEQAL
                     PHWDLDGTAYIRNKSNTKIMIDESLHSPIDAIKAIKKNAVDTFNIKLMKSSGIYPAIK
                     INNIAEASGVNCMLGCMLETRIGITAAANLIASKKNITEADLDSFMFCEELEGISGGF
                     VMDGDIMNLVNKPGLGIEVNL"
     gene            12108..13268
                     /locus_tag="PC494_002304"
     CDS             12108..13268
                     /locus_tag="PC494_002304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF819 family protein"
                     /protein_id="HDF3912800.1"
                     /translation="MNTLFSNPGSILAVMTSMIALGFYLQRYKAIKSLGPALTIIIMG
                     IILSNLKVVPVSTELYGTISTYAIPISMTIMLMSVDLKEMTKLSREPLIAIFVAVLTV
                     SIMAFLFGLVFAEKISEGWKVAGMFVGTYTGGSANLTAIGTGLNVSRQTLAAANAADY
                     VIGVPTLIFMFALPAILKNSKKFKKLWPYHVEESELEDCQNEEFMESKEWSIKDIAWM
                     LAIGFVVTEVSTILAGYFNSSFSSAARILLVTTISIIIAQLKPVKKLKGNLDLGLFVA
                     LFFLCTIGFSVDIKEFLGSTFTITLYCFSIIFASFVFHLGITRLLKIKYQYVILSIVG
                     AIADGPTSALVAASAKWNSLVSVAVVMGVIGGVLGNYAGISVAYAIKMSLGL"
     gene            13281..15377
                     /locus_tag="PC494_002305"
     CDS             13281..15377
                     /locus_tag="PC494_002305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CocE/NonD family hydrolase"
                     /protein_id="HDF3912801.1"
                     /translation="MIKFKLYISGLYSGNVIFDGDLLIEKLNPFTNKIESLKPISKEE
                     NTYYLNLTKIDLKSLFNNFDVYTKSLVNTDKDTVINNLGETHSKLNEYIWVQRNKKFP
                     LDIIIVDNKIVGFICLSRETCTILIMDGYEEYTVLKEWEKTHKNEEIYSIRFGGNYMI
                     DMKDGIKLSTDVYLPDFVDSAKKAPTILMRTPYGKENDKEIYYKYVQRGYAVVIQDVR
                     GRNESEGKWEPMIHEREDGDSTINWIVSQEWSSGIVGMLGASYLGYVQWAAASSGNKH
                     LKALVSIVTSGSPFIDIPRKGGAFVSGMLAWAFMVSRNKVDRSKMVRDDWDDVLNIRP
                     IENIPVEALGYRIEFLEEWLKRVEKDEYWDLMDWHLQKDKINVPALVVSGWYDDNSMG
                     TTEALDVIKDYEKGKRKAILGPWMHNSNTLRDINGISLGNSSLRYDLDYNYLLWFDKY
                     LKGIENNIDTTAPVEYYSVGSNKWKTEENWPIINKIDKSMYLISDGNANTSLGNGRLV
                     FDNDLEEKYDSYIYNPKDPSVQLIDMSENEVGVPNNYKDLEKRSDMLCYTSDAFSEEF
                     TVTGDIKLEFFASSSAKDTDWVIKIMDVDLDGNSIKLADGILSARFRNSFYKSEFMEE
                     GEIYKFTIITSKISNTFKVGHKIRLDITSSAKNFIFQNSNTTEGYNSIEYIEAKNTIY
                     HGGKYPSKLILPIENK"
     gene            complement(15536..15880)
                     /locus_tag="PC494_002306"
     CDS             complement(15536..15880)
                     /locus_tag="PC494_002306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HDF3912802.1"
                     /translation="MEIKRYEGTGRMSRAVVHNNTVYLCGQTHAEGGVIEQTTEVLAK
                     IEDLLNKYGSDKQHLLSVTIYLRDMKDFEAMNSVWDAWVEKGFEPARACVEARLAREH
                     LLVEMSVVAATK"
     gene            16172..17062
                     /locus_tag="PC494_002307"
     CDS             16172..17062
                     /locus_tag="PC494_002307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HDF3912803.1"
                     /translation="MSSTIKSNRIKGIMFIIASALGFAMMSAFVKLAGDLPSFQKVFF
                     RNLVSAIIAFWLIIKHKGSLTGKKENLKVLLYRSIFGTLGVIFNYYAIDKLMLSDANM
                     LNKMSPFLVVIFCAIALKEKINVKQIGAIIIAFIGALFIIKPTFSVEVIPYLGGIAGA
                     VFAAMAYTCLRVLGDREDYYTIVFFFSVFSLVTVGPIAFAVYEPMTLMQLIYLLLGGV
                     FASLGQFGITLAYKYAPAKEISIFDYSNIIFSAILSIFLFNVYPDMLSVVGYLIVFSA
                     AFYMFLYNKKLDKLDKEKKK"
     gene            17280..18566
                     /locus_tag="PC494_002308"
     CDS             17280..18566
                     /locus_tag="PC494_002308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HDF3912804.1"
                     /translation="MEKVKVAVIGAGNRGTYAYAPYIYENSDVCEIVAVAEPKKGRRE
                     LFTQKYNLDSKNVFETLEDFFKHDKMADAVIIATNDDRHYDVAKLALEKGYHVLLEKP
                     MSNSLDGLVHIDDLCDKYKDKIFMICHVLRYSPFYNKLKEIVESKKLGELVSIQYNEN
                     IGYWHFAHSFTRGNWRNSNETSPLILAKSCHDMDILLYLVGSRCKKISAFGSLKHLNN
                     QNASGEMAQNCLQCLVEKKCPYSAKRIYLEKDRSINRAVHINPTEENLLNILKTSPYG
                     RCVYRCDNNVVDNMVNILQFENGVTATFNLCAFTKENGRTIKLMFSHGEVGGDLNKNE
                     IRIKEFGKNEEIVMNPSNQQNMVEEYDRNLIAEFIKLVSNKELEKGRVAAKEAIQSHV
                     MAFAAEYSRVSDEVVYIEEFFDSAKQMTKEIEETIF"
     gene            complement(18655..19098)
                     /locus_tag="PC494_002309"
     CDS             complement(18655..19098)
                     /locus_tag="PC494_002309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="regulatory YrvL family protein"
                     /protein_id="HDF3912805.1"
                     /translation="MIKISNKRRIPLGEFISVFLFFAVFFGITFCIFTVIGIGFLSFL
                     GFEYKSLGAVLIFFLIYFCITTPIDFLCTTILDIFRYVNKLPYSIYKLCEFIIDFILT
                     FLAMNIIDTFMDSVTIPLSTEILFALLSYLLSECMDFFDRDKKKP"
     gene            complement(19122..19916)
                     /locus_tag="PC494_002310"
     CDS             complement(19122..19916)
                     /locus_tag="PC494_002310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M55 family metallopeptidase"
                     /protein_id="HDF3912806.1"
                     /translation="MKLYLSADIEGTCGIVNWDETKLECEFSQHYRTQMSKEITAACD
                     GATQSGVHEILVKDAHDSGRNINPNILPENVKILRGWTKDPLVMMAGIDESFDACIFT
                     GYHSGATCNGNPLSHTMDIDYDYFKINDEIASEFTINAYIAAYYNVPVAFLSGDEMLC
                     ESAKKLNPNIVTVPVSKGIGNGSISIHPNLALKKIEKGVKKALSGDLSRHLIKLPDKF
                     KIEIKFREHYKAFKASFYPNMKKIDSQTVLFETEDYYEFLRMLLFI"
     gene            complement(20482..20958)
                     /locus_tag="PC494_002311"
     CDS             complement(20482..20958)
                     /locus_tag="PC494_002311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase"
                     /protein_id="HDF3912807.1"
                     /translation="MKEILINPIGKICIQGEEVFIKLDKKYVPALNELDDFSHLNVFW
                     WADGFDNPELRSILETPKPYKSGPDVIGIFATRSPIRPNPIALTAVQIINIDHENGII
                     KIPYIDANDNSPVIDLKPYTPSVDRVENPSVPKWCSHWPKSVEKSGEFNWEDEIEF"
     gene            complement(21059..22228)
                     /locus_tag="PC494_002312"
     CDS             complement(21059..22228)
                     /locus_tag="PC494_002312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HDF3912808.1"
                     /translation="MLNIKTLCHEINDWVINIRRDLHKTPELGLEEFQTKKKIIKYLN
                     EIGINYIEYKNHTGITAYINVSPNFETVAIRADIDALPITEELNYSYKSINIGKMHAC
                     GHDAHTAILLGTCNILFKLKDYLNVNVKFFFQPAEETIGGAQLMIEDGCLEKPNVKYI
                     FGLHVNPNINKNLIELKYNTLNASTNTLQLTVHGSKCHGAYPHQGIDAIVISAHIITA
                     LQTIVSRNTNPTDSVVISLGKIEGGIKENIVCDKVVIRGTLRTLTPETREFSKKRIRE
                     ICDFTCKTFGGSISVEIEEGYPALINSNHLVDYVKQNAVELFGEENIILKDSPTLGAE
                     DFSYFLRHCEGAFYHLGCANREKNITSPLHTSTFDIDEDCLITGVMLHVKNVLSF"
     gene            22391..23254
                     /locus_tag="PC494_002313"
     CDS             22391..23254
                     /locus_tag="PC494_002313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase"
                     /protein_id="HDF3912809.1"
                     /translation="MLGIIAPSGPLRNTSLEEIKFNLESYGYEVKFSESCSLNYKGYL
                     AGNDDIRARDIEDMFLDKDVDIIMCLRGGYGTTRILDKINYDIIKQNPKPFIGFSDIT
                     GLNLAFYKNCGLLPYHGIMAANVGKWGKFTYKSLVNALEFKDELYLENPKEEKIYTVC
                     EGKAEGIIMGGNLSLIIATMGTKYEIDAKDKILFIEEIGEPQYKLDRMLTQLYSSGKL
                     EECNGIIFGDFKDCIEENDLMELLIEFANKVNKPSIYNLQSGHCIPMITIPLGRMCEL
                     DATEKIVKLKK"
     gene            23325..23918
                     /locus_tag="PC494_002314"
     CDS             23325..23918
                     /locus_tag="PC494_002314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3867 domain-containing protein"
                     /protein_id="HDF3912810.1"
                     /translation="MSDDRIIDFNELKNKVKDSDVDKFEQYIYNLYFSVMDGKMSMAE
                     FSRKIFDYMRDNNISQEKFMKIQKQFMERYGMDTEEVEKQLRNFGIDPSTAGFMSNNT
                     SSKVSTEDLESFKKSAGFYEKYGEKIQPKSCITTFIKNDLNDINVIIDQEKIMLCSDR
                     KINLMDSELNEFLLEYKNMFNKKIKVVMCETTNKYDY"
     gene            complement(24169..24804)
                     /locus_tag="PC494_002315"
     CDS             complement(24169..24804)
                     /locus_tag="PC494_002315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HDF3912811.1"
                     /translation="MDNLLNELEALKSNLDNLPIEKIENYDLSKTALFIIDVNNGFAR
                     QGALYSPRVESLIKPIEMFTKKISNKLNRVIAFTDSHTPKSIELLSYPVHCLENDVES
                     ELVDELKSIENLQILPKNSTNGFFALENLDFDNIDNIIIVGDCTDICIYQFAITLKSY
                     FNQHNIEKNIVVPMNLVDTYDIPNVHPAEILNLVFFNSMIQNGVNVLKEIR"
     gene            complement(24884..25615)
                     /locus_tag="PC494_002316"
     CDS             complement(24884..25615)
                     /locus_tag="PC494_002316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HDF3912812.1"
                     /translation="MNIYAHRGFSGKYPENTILAFKKCLDMDIYGIELDVHRTKDGKI
                     VVIHDEKVDRTFNGHGFVKDFTLRKLKTLNSSFEGYQSNKECKIPTLEEVLILISPTD
                     LTLNIELKTDKINYPNIEKGVLELILKYNMKNRVLISSFNSNSLKNFHKLDPSVKTGL
                     LCYLPINNVVNFAKFLGNSYLHPPLVLVNESLIELCHKNLLGVNVYTVNEEDDILHCL
                     KLNVDGIFTNYPDIASNLLHSKQYS"
BASE COUNT         9532 a         3122 c         4201 g         8827 t
ORIGIN      
        1 ttatctagtt ttattttctt tatagaacaa taatattata aatgctagta gatttacaca
       61 gaatactgtt atatacatct gtttaaatcc tgagtttaga gtagattgta gtgtgttttc
      121 tatttttgtt ctattatttt ctatggaatt tatataatcc aattttgatt tatcaaaagc
      181 ctttggtatt tcagttttta cctcttgtgt ctttgctaaa actgcttgga gtgatttttt
      241 ttgctgttgc attgtatcaa ggcttttttc catgtctttc ttttggctta tagaattatt
      301 taacttgctt tgtagctctt tcttttgaga ttccattgat cttagttttt tacttaattc
      361 gttcttttga gttttatttt tttgtaactt tgtatttaag tcatctcttg tcttttttag
      421 ttgctgtatt tgagcattta aactttcttt ttgttcattt acatttggtt tattctcgct
      481 ggaattgtta ttcttatttt ctgtagaatc attcttagtg tcgtctgatt cagaattact
      541 ggtattactc tggttttgtt catttgagtt attttcgtta tcagtaggag ttttttctgt
      601 agtaggtatt ttattataag cagttgtaag ttccttgatg gcctcatctt gtttttcaag
      661 accttgttcc atacctttta tacctttatc aacaccagca ataccttttt ttacaccatc
      721 tattccttga ttaataccag ctctagcttt taccatattg tcaataccag tttgaactcc
      781 tttaatacca ctatttagtt tattttcacc atcttcaata ccgtttattc cactttgtgt
      841 tccatctatt cctttttgta catttttctg tattttagta attatagatg gaactttttc
      901 atcaaacatt gttgttgata tttcttttgt tatattggta atgttggttg tatctgctga
      961 ctgaacttta ttaagtaagg attttggaag tttgccacct gtcatgtcca tatttatatt
     1021 tgaagtatca ttcatatttg ggatagagac attttttaaa ttttttgcca tttcagggtc
     1081 tgattttaag tcatctatca tgttttcaag ttcttcaagt tgaactattt taggagttga
     1141 gggctttcca actaagtcca taatattatc ttgcacagat aatcctgcat gtgctataaa
     1201 tccaatcatt atagctggag aaattgaagt accaattgag cgtatcaagg ataatgttgc
     1261 aagtgctgaa ttagattctt ctaatcttgt atttgataac atcatatagt ttagaggagt
     1321 tcccatagta aatcccattc ctaatcccat aaatattaaa cttacacata cactaaatac
     1381 agtattggtt tttagagcaa ttaaaactag gtaaagagag cctatcatag atacagaaaa
     1441 tcctagtaat agtatttttt ttgccccaaa cttgtcaata agtcttccgc ttaaaggagc
     1501 agcaatacct gcaaataatc ccaatatagc tacaaaatat cccccagaac cagcatttat
     1561 ctttaatgca ttttcagcat actgtggaac gaataccata cccatcattc caataccaac
     1621 aattaaagat aaaataagta ctatcaatat tctcggattt aaaaaatatt caaagcttaa
     1681 aatagggtct ttagctctat tttcaataaa tatgaaaata ggtataagta caataaatgt
     1741 caataagtat ggataaactg atatatcttg tatagaattt ttaaaattaa aaaagtctat
     1801 attcataaga ccatataata gtgatacgat tatacatatc aacatcaatg taccaagctt
     1861 atctattttt tctttagatt cagacttatt gtttttaata cagaaaactc caccaataag
     1921 tatgattaaa caaattggaa gatttacaaa aaatagccac ttccaatttt gagttccaaa
     1981 gatacttaga attgtgctac caatgcttga acctaaaata ttggcaatac catatgttgc
     2041 cccaactaaa cctaaagcca tgcctctttt attttctggg aaggtagttc caaattctgc
     2101 tgtagcaatt ggcatgattc caccaccacc aattgcttga ataacacgac caattaataa
     2161 aatatagaaa ttggaaaata gtgatgataa tccacatatt aatgaaccac taccaaatag
     2221 aaatatacta actagataca catattttct tcctatttta tctgctaatt ttccagagat
     2281 aggaattaca gaagcgtatg ttaatgtgta tatggtaatc atccaaattc ccgttttttc
     2341 atttactcca aggctatttt gtataatcgt tcttgctggt gatactattc cagtatcaat
     2401 agctcccata aatataccta atagataaag cgtaagtact aaaaatattt ttggattact
     2461 gtccttgttc ttaatactag tattatgatt caaggtaaac accaccttaa tgtattaatt
     2521 tttcaatata gggttttaaa tcttcaaatt ctatatgaag atatgttgaa tatgaaaaaa
     2581 acatttttat tatgatattg catactaatt tgtcattatt aaaaaaactt tctttttcta
     2641 aagcttcata tactttattt gaaagctgtt catgaaagtc gtctttgtgt tttttcattt
     2701 caaaaaatct ctctgtttca aaagtgttta aaaagtcatt gtattggata ttatgaactt
     2761 tgtttataaa atttcttatt tcagtaaaaa taatgtttag tttttttatg taatcttcag
     2821 tgtttttatt ggagtattca attcgcctta tcaataaatc ccattcagat tttgtgatat
     2881 attctattat ttcttgtttt gaattaaagt aattatacac tgtacctgca cttataccac
     2941 acctttgagc tattttcctt atgctaatat tcgagtaatc ttcttctaaa atcatatccc
     3001 gagacacttt taatatatct tcttttacat tttctaaaat ctttggcata ttaccacctc
     3061 ttttattaaa attattatga acactgttta ttatactcct ttaaaattta ttaatcaata
     3121 tgtaagctat aatgtataat attattatat agatatgata gaaaataagt gtcttcttac
     3181 taaatatcta ttatattaaa tttgtactta agtatgatta tttattgaaa tatgtgatat
     3241 taaatttttc tttttaataa attaaatatt atatgataag gagaatatgg tgatggaaaa
     3301 gaagtatgta atggcattag accaaggaac aaccagttca agagctatac tatttaataa
     3361 aaaaggcgaa atagtgaaaa ttgcacaaaa agagttcaat caaatttatc caaaagctgg
     3421 atgggtagag catgacccta tggaaatatg ggggtcacaa agtggggtaa tgagagaagt
     3481 tatagaaaca gcaggtataa gaccagaaga aattgcttca atagggataa ctaatcaaag
     3541 agagactacg gttgtttgga gtaggtatac tggtaaacct atttataacg caatagtatg
     3601 gcagtgtagg agaacgtcag aaatatgtga tgaacttaaa aataaaggat tggaagaatc
     3661 aataaaagaa aaaacaggtc ttttaataga tgcatacttt tcagcaacaa aagtaaaatg
     3721 gatattagat aatgtagaag gagctaggga aaaagcagaa caaggagagt tattatttgg
     3781 aactatagat acatggttaa tatggaattt aactcgtgga aaagtacatg taacagatta
     3841 ctcaaatgca tctagaacaa tgatgtacaa tataaatgat ttagaatggg atgaggatat
     3901 attacgagaa ttggacatac caataagcat gttgccatta gtaaaacctt ctagctatgt
     3961 ttatggtcat acagatgagc gcatgttatc aggagctaaa atacctattg cgggatgtgc
     4021 tggagaccaa caagcagcat tatttggtca aaattgtgtt gaagaaggta ctgcaaaaaa
     4081 tacttatgga acgggttgtt tcttgcttat gaatacaggc agtaacatag ttaaatctaa
     4141 gcatgggtta cttacaacaa ttgcttgggg agttgatgga aaagtaacat atgcattaga
     4201 aggaagtata tttattggag gagcatctgt tcaatggctt agagatgaat taaagataat
     4261 tgaatctgca aaagatagtg aaatgtatgc aaatagggta gaggatacta atggtgtata
     4321 tgtagtgcca gcatttacag gtcttggagc tccatattgg gatatgtatg ctaggggttc
     4381 aattttagga cttacaagag gagcaaaaaa agaacatata gtaagagcca cattggaatc
     4441 aattgcttat cagacaaagg atgttttaga agcaatgcaa aacgattcaa aattaaaact
     4501 aaaatcatta aaagttgatg gtggagcaag taataataat tttttaatgc aatttcaatc
     4561 agatatatta aatgtagata tagatagacc caaaatagta gaaactacag ctttaggagc
     4621 tgcttattta gcagggttgt ctgttggatt ctatattgga agaaatgaaa ttacttcaaa
     4681 gtggtcagta gaaaaagagt ttaatccaaa tatgagtgaa gagaagagat gtaaattata
     4741 taaaggatgg aaaaaagctg tatcgagagc tttaagctgg gaaaaagaag atgaattgga
     4801 tatttaaaaa ttaatcaaag ttaaatttat ttgaatttaa aaagagcttt atgtaaaata
     4861 tgaagctctt tttttgttgt taatcttgca tttttatata atcacactaa attatataat
     4921 ttatttttcg ttttcatata aaaacattgg tatagaattg taaatgtgtt ggtcaccaac
     4981 tactaagaga atgtctcctt ctaaaaattc aatatatggt ccaggagata ttataagttc
     5041 ttcacctctt ttaattgcaa ctattgtagc acctgtattt tgccaaaatt tagtttgtgc
     5101 agctgtttga ccaatatatt tgcaattaga atttatggtg aactgaacgg gcactaaagg
     5161 attgattatt tcaagtctgt tagaatagtc taaaatttta tttatagtat ctaatatttc
     5221 attttctaaa ttagatttag tatctattaa attataaagt gttgatttat atgatgatat
     5281 atttgtaata tctctatatt tttttataaa agaagaagct ttgtctggag atagtacaat
     5341 aacaccttta ccctttatgc ttttaacaac gccaatgtcc tctaaaattt tgacagctct
     5401 tcttatcgtt tctggagata cattgtattt accagccaaa acagagcgtc caaatagtac
     5461 tgaatcctct tgtatttcac ccgtgtatat tttatttgca atatccaacg ctattttttg
     5521 gtatattggc atcgtatagt ttttatccat tgtttttccc ccaatacaaa atttatgtta
     5581 aaaaaatata taatcttaac aatactattg tataatttat aggtttatat gtctacaata
     5641 tgtacaaata ttgtgcatgt tttaaaataa tattttaaca tgcatttagt atacatgatt
     5701 ttattatact taaaactata taaagaatta attataaaaa tataaagata ttttacttac
     5761 aaagaatgat aattatatag atgaaagaaa caaatgaatg aagaaaaatg attctgtctt
     5821 gcatataaag tgattaaaaa tgaaaaatac tttaaaaatg aaggttaaag cccttatttt
     5881 aagtgaaaat aattaattat taactaaaaa atggtaaaaa gattttttga aaaagaaata
     5941 caaatgaatg ttcaattaaa ataattgcaa aaatattcct taaatggtaa aattatatta
     6001 attaaatgca atagaatagt tgcaaaaata aaattgaata caagtgataa aatatttcat
     6061 gcaatatata aaataaacaa aatttaaaaa ttaaaactac ttattctatc aaaatgttag
     6121 cgaggagggg tcataaattg tataaagtag atttaaatag tgatttagga gaaagttttg
     6181 gaacgtataa gattggttta gatgaagaag ttttaaaata tatttcatca gccaatatag
     6241 cttgtgggtt tcatgcaggt gaccctagtc atatggaaaa aacagtacag ctagctaaaa
     6301 aaaatggagt gaaaataggc gcacatccag gtttcctaga tttaatagga tttggaagac
     6361 gtgagatgaa aataacaaag caggaagcta aagattatac aaaatatcaa ctgggtgctt
     6421 taatggcatt tgcaagttca aatggatgta atatacaaca tgtaaaacca catggagcat
     6481 tatacaatat ggcagctaaa gataaagagt tagctatggg gatttgtgaa gctatatatg
     6541 aagtcgataa agatattata ctgttggggc tatataatag tgaaatgata aattctgcta
     6601 aagaaattgg acttaggttt gcaaatgaag tatttgcaga tagagcttat gataataatg
     6661 gttttttggt tccaagaaat gtagaaggag cagttataca tgatacaaaa catgcaatag
     6721 atagggttgt taggatggta aaagaaggaa ctgtagaaac tttaacaggt gaagttatac
     6781 atatcaaagc agattctata tgtgtacatg gggacaatcc aaaagcaata gagtttgtca
     6841 aagaaataag aaagcgtttt gaattagaag gtatagaagt ttgtccatta gaaaacatag
     6901 aagtttgttc gtcagagaac atagtataag actgataaca tgagggggag ataaaatatg
     6961 agtacaaaaa atattacaga taaaactaaa aataaaaaag atgtcggagc acttataggg
     7021 gctgcattta taatggcaac atcagcaatt ggaccagggt ttttaactca gactgcacaa
     7081 tttacccaag attttggacc gaatttttca tttgtaattt taattacaac aatccttttt
     7141 ataggggctc aagtaaatgt atggagagta attggtgtat caggacttag aggtcaggat
     7201 atagcaaata aaataatacc tggattaggc tatttagtag cttttttagt agctcttgga
     7261 ggattagctt ttaatatagg aaatgttggt ggagctgcac ttggtatgaa tgtaatgttt
     7321 aatatgaata tgacattagg aactgtatta agtggattaa tagctatatt tgtatttatg
     7381 tcaaaaaatt caaattctct agtcgataag ataactaaat ttttagcatt aggaatgata
     7441 attatagttg gatatgtagc aatatcaaat catcctcctg ttggagaggc agtatcaaga
     7501 atggtaaaac cagaaaatcc aaaaggactg atattcccaa taataacttt acttggagga
     7561 agtgttggag gttatataac ttttgctgga ggacatagat taatagacgg tggaataaca
     7621 ggagaagaaa atataaaaga aataactaaa tcttctcttt tgggtatatt agttgccaca
     7681 atgatgagag ttcttttatt tttagcaata ctggcagtgg tttcaaaagg tcttcaactt
     7741 gacccagaaa atccagcagc ttcagctttt aaatttagtg caggagcaat aggatataaa
     7801 ttctttggac ttgtattatg gtctgctgca attacatcag ttataggagc tgcttataca
     7861 tcagtttctt tcttaaagac actaaatcct tttatagata aatatgaaaa atattttata
     7921 atagcattta tagcaatatc aacacttata atggcattta taggaaaacc agctacttta
     7981 ttaattttag caggagcttt aaatggattg atacttccaa tcacattagg aattatgctt
     8041 atagcatcta aaagaaaaga tattgttgga gattacaagc atcctacatg gcttttaata
     8101 tttggattaa tagtagtttt aatatctgca tatacaggaa taacttctct tagcagccta
     8161 ggtgctttat ttgcttaatt tagaagaggt gacatttatg gaaactagat acttgatatc
     8221 aggggataag gcagtggttg ctgaatttgg aaatgagata tcagaagata taaacaaaaa
     8281 agtaatttca tttatgagag caatagaaat atcgaatctt aaaggtattg taacagaaat
     8341 ggtaccaaca tataggtcac ttatgataag ttataatcca ttagaaatag attttgatag
     8401 tttgattgag aatttaaaaa aaatagaaga taatttggaa agtatagtat taccaaaacc
     8461 taaaatacat gagattccag tatgttatga tgaggttttt ggtatagata ttaaaaacgt
     8521 tgcaagctac aataatctca ctgtagatga agttataaaa atacacacaa gcagagagta
     8581 cttgatatat atgctaggtt ttactcctgg atttccatat ctaggtggta tggatgaaag
     8641 aatagctaca cctagattag aagtgccaag gactaaaatt tatggtggga gtgttggaat
     8701 agcaggttcc cagactggtg tatatcctat tgatagtcct ggtggatggc aaataattgg
     8761 taggacacct ttaaaattat atgatgaaaa tagagaagaa cagattttgc ttagagctgg
     8821 agattttata aaatttgttc caataacatt agatgaattt atagaaatcg aaaaaaataa
     8881 cttaagtatt taaatatcgt tatagtacag ggagtggtat atatgggatt caaagttgaa
     8941 ttaggaggtt tccaaacatt aatacaagac agaggtagag ttggctatgg tcaatatggt
     9001 gtatctggat gtggagcaat ggatgagtat gcacatagag taggaaatat attagtagga
     9061 aattctgaag atgaggcttc tttagaagtt ttaatgttag gtcctacaat tacctttgat
     9121 gaatatacgc aaatagcagt aactggggga gatttagggg ctaaaataaa tggaaaagaa
     9181 attcaaaact ggaggtcata tcaaataaat ccaggtgatg tattatcatt tagaggtgtg
     9241 aaatcaggtg ctagagccta tgtgtcaata gctggtggaa tagatgttcc acttgcaatg
     9301 ggaagtaagt caacttatac aagagctaaa attggtggat ttgaaggtag agcacttaaa
     9361 aaaggagatt atataaatac ttttattcag gaaaaagatt ttacaataaa taaaaaatta
     9421 agttcaaaat atattccaac ttatagttca gaaatcgtac taagaattgt aaaaggtcct
     9481 caatttgatg ctttttctaa cggtgaagta gagaaatttt tatcaaataa atacaaagtt
     9541 acgaatgaaa tagatagaat gggttgtaga ctagatggag agagtataaa gcaccttaat
     9601 ggagcagata ttatatctga tggtatttct tatggagcta tacaagtacc tggtcatgga
     9661 aaaccgatta taatgttatc agatagacag actagtggtg gctatactaa gatagggaac
     9721 gttataagtg tagatttgta taagttagca caagcaaagc caaatgatgt agtaaaattt
     9781 gaacttgtag atatatatga agcacataga ctattgagag agcaagaaga taagattcaa
     9841 gatatctaca agagtatgaa aaatataaga gttgtaaagg caaaagtatt aaatgatata
     9901 gcagtttaat tttaacaaat acaattttta ttataattta taatataact tacaaatagc
     9961 tatttactat ttaccataat taagatggtt tagattagtc aaatagctat ttttttagtt
    10021 tgagtaaata ttttaaattt aaaataaaag caatatttaa atctattata ttatctacaa
    10081 aaagtaggtg tgtcatattg agtttattta gattttattg gccaaattgg aggtgatata
    10141 actccatatc cacgagctat tgtatcttta cttggattga tgattttatg tggtacatta
    10201 gcttttataa atgttgagtc acctggattt aatctaacta ccttttcacc catacaaata
    10261 tcaaccacac cactcgttac caccataatt tcttctgatg catgatatat ataatctttg
    10321 gcatcctcac tttctggttt aagttcaaac tctacaaata aaattgaagg tgtaaactca
    10381 gttgtaggca ttggagatac tatctcgtaa aacatttcac tctttggaaa tttcatcata
    10441 actctatctt cttttctaat gactaaatca tcagtattat tgtcatccat aaacatatat
    10501 aaaggagtgt ctaaaacttc agcgattttt ctcaatgaag acaaggatgg ttcaatagca
    10561 tctctttcta tttgagagat ataacttata gataaatctg tcaatttgga aacatcactt
    10621 aatgtttttt tcttgctttt tcttatattt ctcatctttt cacctagcat aagaacctcc
    10681 aaataataaa attaatataa aatattcgct taaaacaaag taattatagc acaacataga
    10741 agtagtggca ataagaatac atagtagatt ttgacaatta aaatttaatt aaatccaaat
    10801 aaaagtctat gaaaatgaat tattgttaaa ttaatacaaa gaaaataata ataaaaaaat
    10861 ttaatagaag agtattaatt gaattaagat tatcacatta tattttggaa aagagtaaat
    10921 tttcagtaaa ttatcttgac atatatattg aagtaataat ataatttaaa gtataaaatt
    10981 ttaaaaattg aattataact tcaaaaaata aggagggtaa tatgaagata acagatatca
    11041 aatttgaaaa gcttagaatt aaattaaaaa aacctgtagt agtttcattt ggagtaattg
    11101 agtatggaga aagtataatt ttaaaaattg aaactgatga agggtattgt ggatttggcg
    11161 aagcagcacc tcttgcagca gttacaggtg aagttttgga taatgttctt tcagtattgc
    11221 ttatgtttaa aaaagagtta ataggcaaag acccactaga tattgaaacc atacatacca
    11281 tcatggatgg aattattata ggtaatactt ctgcaaaagc agctattgac atagctttat
    11341 atgatattaa aggaaaaatt atgaatgcac ctctttataa agttcttgga ggatttgata
    11401 gtaaagtcca aacggatatt actataagta tagataagcc agaaaaaatg gcagtagaag
    11461 ctttagaaag agtaaaagaa ggttttagga tattgaagct taaagcaggt ataaatcctg
    11521 aagacgatat tgaagctgta aagttaatta gagaagccgt tggagagagt ataagaatta
    11581 gaattgatgc aaatcaagga tggaacgtaa atagcagtat aaatactatc aaaaagttag
    11641 aagaatttaa tgttgatgca attgaacaag cacttccaca ttgggattta gatggtactg
    11701 cttacataag aaataaaagt aacacaaaaa ttatgataga tgaatcatta cattcaccaa
    11761 tagatgcaat taaggctata aaaaagaatg cagttgatac atttaatatt aagctgatga
    11821 aatcaagtgg aatatatcct gctataaaaa tcaacaacat agctgaggca agtggagtaa
    11881 attgtatgtt aggatgtatg ctggaaacga gaattggtat aacagcagca gcaaatttaa
    11941 tagcatctaa aaagaacata acagaagctg accttgatag ttttatgttt tgtgaagaat
    12001 tagaaggtat atctggagga tttgtaatgg atggagatat tatgaatctt gtcaataaac
    12061 caggtttagg aatagaagta aacttatgat aaatttggag gttaaatatg aatacacttt
    12121 tttcaaatcc aggtagtata cttgctgtaa tgacatcaat gattgcattg ggtttttact
    12181 tacaaagata caaagccatt aaaagcttag gaccagcact tacaataatc ataatgggaa
    12241 taatactttc aaacttaaaa gtagttccag taagtactga gttatatgga actatttcaa
    12301 catatgctat tccaatttct atgactataa tgttgatgag tgttgactta aaagaaatga
    12361 caaaattatc aagagaacct ttaattgcaa tttttgtagc tgtattaact gtaagtatca
    12421 tggcattttt atttggatta gtatttgcag aaaaaatatc agaaggttgg aaggttgctg
    12481 gaatgtttgt aggtacatat actggtggaa gtgctaatct tacagctatt ggaacaggtc
    12541 ttaatgtaag tagacaaact cttgcagcag caaatgcagc agactatgta attggagtac
    12601 caacattgat atttatgttt gctctaccag caatattaaa aaattcaaag aagtttaaaa
    12661 aactttggcc atatcatgta gaagaatcag aattagaaga ttgtcaaaat gaagaattta
    12721 tggagtcaaa agaatggagt attaaagata tagcttggat gttggctata ggttttgttg
    12781 ttacagaagt ttcaacaata cttgctggat atttcaattc aagttttagt agtgcagcaa
    12841 gaatactttt agttacaaca atttcaatta taattgctca attaaagcca gtaaagaaac
    12901 taaagggaaa tttagattta ggattatttg ttgcattatt ctttttatgt acaataggtt
    12961 tttcagtaga tataaaagag tttttaggtt caacttttac tataacactt tactgtttta
    13021 gtataatttt tgcttcattt gttttccatt taggcataac tagactttta aagataaagt
    13081 atcaatatgt aatactttct atagtaggag caattgctga tggtcctact tcagctttag
    13141 tagctgcttc tgcaaagtgg aattcgcttg taagtgtagc agtcgtaatg ggagtaattg
    13201 gtggagtatt aggaaattat gcaggtatat cagtggcata tgcaataaag atgtctctag
    13261 gattataggg gggagtttaa ttgataaaat ttaaattata catatctgga ctatacagtg
    13321 gaaatgtaat ctttgatgga gatttattaa ttgaaaagtt gaatcctttt acaaataaaa
    13381 tagaaagttt aaaaccaata agcaaagaag aaaatacata ttatttaaat cttacaaaaa
    13441 tagatttaaa gtctttattt aataattttg atgtatatac taaaagctta gtaaacacag
    13501 ataaagacac agttataaat aacttaggag aaacgcattc taaacttaat gaatatatat
    13561 gggttcaaag aaacaaaaag ttcccactag atataattat tgtagataat aaaatagtag
    13621 gttttatctg tttatctaga gaaacttgta ctatattaat tatggatgga tatgaagagt
    13681 atactgtatt aaaagaatgg gaaaaaactc ataaaaatga agagatatat tctataagat
    13741 ttggtggaaa ttatatgatt gatatgaaag atggtataaa actttctaca gatgtatatc
    13801 tccctgattt tgtagattct gccaaaaaag caccgacaat tcttatgaga actccatatg
    13861 gaaaagaaaa tgataaagaa atatattata aatatgtaca aagaggatat gctgttgtaa
    13921 tacaagatgt taggggaaga aatgaatcag aaggtaagtg ggaacctatg attcatgaga
    13981 gggaagatgg agatagtacc ataaattgga tagtatcaca ggaatggtca agtggaatag
    14041 ttggaatgct tggagcatca tatcttggtt atgtccaatg ggcagctgca tcttcaggca
    14101 ataagcatct taaagcttta gttagtatag taacatcagg aagccctttt attgatatac
    14161 caagaaaagg aggagctttt gtatctggta tgcttgcatg ggcatttatg gtatcaagaa
    14221 ataaagttga tagaagcaaa atggtaagag atgattggga tgatgtttta aacatacgac
    14281 caatagaaaa tatacctgtt gaagctcttg gatatagaat tgaatttctg gaagaatggt
    14341 taaagagagt agaaaaagat gagtattggg atttgatgga ctggcattta caaaaagata
    14401 aaataaatgt acctgcattg gttgtatctg ggtggtatga tgataatagt atgggaacta
    14461 cagaggcctt agatgttata aaggactatg aaaaaggaaa gagaaaggct attctaggtc
    14521 catggatgca taattcaaat actttaagag atataaatgg tatttcttta ggaaatagtt
    14581 cattaagata tgatttggat tataattatc tattatggtt tgataaatac ttaaaaggta
    14641 tagaaaataa catagatacg actgctccag tagagtatta ctctgtaggt tctaataagt
    14701 ggaagacaga agaaaattgg ccaataataa ataagataga taaaagtatg tatctaataa
    14761 gtgatggaaa tgctaacaca tctttaggaa atggtagatt agtatttgat aatgatttag
    14821 aagaaaagta tgatagttat atatataatc caaaagaccc atcagtacaa ctaattgata
    14881 tgtcagagaa tgaagttgga gttccaaata actacaaaga tttagaaaaa agaagtgata
    14941 tgttgtgtta tacatcagat gcttttagtg aagaatttac tgtaacaggt gatataaagt
    15001 tagagttttt tgcatcaagt tctgccaaag atactgactg ggttataaaa attatggacg
    15061 tggatttaga tggaaattca attaaattag ctgatggtat acttagtgct agatttagaa
    15121 atagttttta taagtcagag tttatggaag aaggagagat ttataagttt acgattataa
    15181 cttcaaaaat atcaaacacg tttaaagttg gtcataaaat tagactagat ataacgtcta
    15241 gtgctaaaaa ctttattttc caaaatagca acacgacaga gggatataat agtattgaat
    15301 atatagaagc aaagaatacg atttaccatg gaggtaaata tccatctaaa ttgatattgc
    15361 caatagagaa taagtaaatt tatatagatt aaatagtgag gaggtgtctc aaaatgaatt
    15421 ttttagttcg tgagacactt tcttttatac gaaatcaaat atattttcat catttcaaca
    15481 atgaaaaaga ggcttatctc tctgttttga gatagcctcc tataagctaa attgattatt
    15541 ttgtagctgc aacaacgctc atttcaacta acaaatgctc tctagcaagt ctagcttcaa
    15601 cacaagctct agcaggttca aatccttttt caacccaagc atcccaaaca gagttcatag
    15661 cttcaaagtc tttcatatct cttaaataaa tagtaacaga tagcaaatgt tgcttatctg
    15721 aaccatattt gtttaataaa tcttctattt tagctaaaac ttcagttgtt tgttcaatta
    15781 ctcctccttc agcatgagtt tgtccacata aataaactgt attgttatga actacagctc
    15841 tactcattct tccagttcct tcatatctct ttatttccat attttaaata cctccatagt
    15901 taaaaaatct attaaaaatc taaataataa attaaaaaaa gtctatacta tataaaatta
    15961 tattatatat tctgataata atccataaaa acatataact ttttagctat aattattatt
    16021 gttattaatt gaaaagattt attagttact tgacatagtt tacactttta attatagtat
    16081 aaattggaat atttagataa ttattattta atgtataagc taagttttta attaatatgg
    16141 ctttatacat ttatatagaa aagaggtacg tatgagtagc acaatcaaat caaatcgaat
    16201 aaaaggtata atgtttataa tagcatcagc gcttggcttt gcaatgatgt ctgcattcgt
    16261 aaagctagct ggagatttac caagttttca aaaagtgttc tttagaaatc tggtatcagc
    16321 tataatagct ttttggctta tcataaaaca taaaggaagt ctaactggta aaaaagaaaa
    16381 tttaaaagta cttttatata ggtcaatatt tggaactcta ggagttatat ttaactacta
    16441 tgcaattgac aagttgatgc tttcagatgc taatatgcta aataaaatga gtcccttcct
    16501 tgtagtaata ttttgtgcaa ttgctctaaa agaaaaaata aatgtaaagc agataggagc
    16561 tattataatt gcatttatag gagctttatt cataataaaa ccaacattta gtgtagaagt
    16621 aattccatat cttggaggaa ttgcaggagc tgtatttgca gcaatggcat atacttgttt
    16681 aagagttctt ggagatagag aagattacta tacaattgta tttttctttt cagttttttc
    16741 attagttact gtagggccaa ttgcttttgc agtatatgaa ccaatgaccc ttatgcaact
    16801 tatatatcta ttactaggtg gagtatttgc aagtctaggt caatttggaa taactctagc
    16861 atataaatat gcacctgcta aggaaatctc tatatttgac tatagtaata taatcttttc
    16921 agcaatttta agtatattct tattcaatgt ctatccagat atgttaagtg ttgttggata
    16981 tttaatagta ttttcggcag cattttatat gtttttatac aataagaagt tagataaatt
    17041 agacaaagaa aagaagaagt aaactagata aaagtgtttt tataatttgt atttaatatt
    17101 taagtctttg tattaaaatt aaagaaaatt taattaaaaa tgtttggtat attaacttat
    17161 aacagcagtt aaaattgaaa aattataact gctgtttctt ttattaaaaa tatccaaatg
    17221 tctgtaaaaa tagactataa tagagtagta taaataatat aaaggggata aattaaagta
    17281 tggaaaaagt gaaagttgct gtgattggag caggtaatag aggaacgtat gcatatgctc
    17341 catatattta tgaaaattct gatgtatgtg aaatagttgc tgtagcagaa cctaaaaaag
    17401 gaagacgaga actatttaca caaaaatata acctagatag taaaaatgta tttgaaactt
    17461 tagaagactt ttttaaacat gacaagatgg cagatgcagt aataatagct acaaatgatg
    17521 atagacatta tgatgtagca aaactagctc ttgaaaaagg ttatcatgta ctattagaaa
    17581 agccaatgtc taatagttta gatggtctgg tacatataga tgacttgtgt gataagtata
    17641 aagataagat ttttatgatt tgccatgtac tgagatattc tccattttat aataaattaa
    17701 aagaaattgt agaaagcaaa aaattaggag agctagttag tatacaatat aatgaaaata
    17761 taggatattg gcattttgca catagcttta ctagagggaa ttggagaaat agcaatgaaa
    17821 ccagcccttt aattttagca aagagttgtc atgacatgga tattttgtta tatttagtag
    17881 gaagtagatg caaaaaaata tctgcatttg gaagcttaaa gcatcttaat aaccaaaatg
    17941 ctagtggaga gatggcacaa aattgtcttc agtgtttagt tgaaaaaaaa tgtccatatt
    18001 cagcaaagag aatttattta gaaaaagata gaagtataaa tagagctgtt cacataaatc
    18061 caactgaaga gaatctattg aatatactta agacaagtcc atatggaaga tgtgtttaca
    18121 gatgtgataa taatgttgta gacaatatgg taaatatact acagtttgaa aatggagtga
    18181 cggctacttt taatttatgt gcatttacta aagaaaatgg aagaactata aagttaatgt
    18241 ttagccatgg tgaagttggt ggggatttaa ataaaaatga gataagaatt aaagaatttg
    18301 gaaaaaacga agaaatagtt atgaatccat caaatcaaca gaatatggta gaggaatatg
    18361 atagaaatct tatagctgaa tttattaaat tagtttcaaa taaagaacta gaaaagggta
    18421 gagtagcagc aaaagaagct atacaaagtc atgtaatggc atttgcagca gaatattcta
    18481 gggtcagtga tgaagtagtg tatatagaag aattttttga tagtgctaag caaatgacta
    18541 aggagataga agaaactata ttttaattaa taaaaattta ttaaataaaa taaagataga
    18601 ttaaataata gaaatacgaa aatatgtgtt ctattaagga atctatcttt tttattaagg
    18661 ttttttctta tccctatcaa aaaaatccat acattctgat aaaagataag aaagtaaagc
    18721 gaataagatt tctgtactta aaggaatcgt tactgaatcc ataaaggtat caattatgtt
    18781 catagctaga aaagttagta taaaatcaat tataaattcg caaagtttat atattgagta
    18841 tggtaatttg tttacatatc tgaatatatc taaaatagta gtgcatagaa aatcaattgg
    18901 agtggttata caaaaatata ttaaaaagaa aattaataca gctccaagag atttatattc
    18961 aaatcctaag aatgataaga agccaattcc tataaccgtg aaaatacaaa aagttatacc
    19021 aaaaaaaaca gcaaaaaata aaaatacaga aataaattcg cctaaaggaa tccttctttt
    19081 attacttatc ttaatcaact ccttaattta tgatatgaaa tttatataaa taataacatt
    19141 cttaaaaatt cataatagtc ctctgtttca aatagtactg tttgagaatc tatttttttc
    19201 atatttggat aaaaagaggc cttaaaagct ttataatgtt ctctaaattt tatttctatc
    19261 ttaaatttat ctggcaattt tattaagtgc ctagataaat ctccagataa agcttttttg
    19321 acaccttttt caattttttt tagtgcaagg tttggatgga ttgaaattga accatttcca
    19381 attccttttg acacaggaac agtgactata tttggattta gtttttttgc actctcacaa
    19441 agcatttcat ctccacttaa aaatgctaca ggaacattat aatatgcagc aatataagca
    19501 tttatagtaa attcagatgc tatttcatca tttattttaa aatagtcata atcaatatcc
    19561 atagtatgag aaagtggatt accattacaa gtagctccag agtgatagcc ggtgaatata
    19621 catgcatcaa agctttcatc aattcctgcc atcataacta gtgggtcttt ggtccatcct
    19681 ctaagtattt tgacgttttc aggtaaaata tttggattaa tatttctacc actgtcatgt
    19741 gcatctttaa caagtatttc atgtacacca gattgagtag ctccatcaca tgctgctgtt
    19801 atctctttac tcatttgcgt tctatagtgt tgcgaaaatt cacattcaag ttttgtttca
    19861 tcccaattta caataccaca agtaccttct atatcagcac ttaaatacaa tttcataata
    19921 tataccccct tatgtttatt attgatgata ataacagata acagaaaata cataatcaat
    19981 aaagggcata aaaatattat gtcttactat taactattat taaatctgta actgaaaaat
    20041 aactaaattg gtataaaaaa atataacact atgtgtcatt tatttatata gttttttata
    20101 tttgatgttt atataaaatt gtaacatata agtggttaca tttactagtt taacatagtt
    20161 aaaatagtta ggtattattt ttaagttaaa ttgattatta taaaatcgca gaataaaaga
    20221 aaaatttaat ttattaaaat gcatgaaatg ttttttcctc aacataatgc taaattaaac
    20281 tcaaaaagaa ataatagaaa aatcttatgt agcttagaaa gaatgtgaat gatttaaggg
    20341 aaaaatagaa atttattata taatattagg ttgtattata taatacagcc taatattata
    20401 tgtatatgtg acataaaatc ttggtaagtg taaataaaat aaatgtggaa aacaagttaa
    20461 tgaaatcaag aaaaaagtaa tttaaaattc aatttcatct tcccaattaa attctcctga
    20521 tttttctaca ctcttaggcc agtgactaca ccatttagga acggacggat tttcaaccct
    20581 atcaacgctt ggagtatatg gctttaagtc aataacagga ctattatcat tagcatcaat
    20641 atatggtatt tttattatgc cattttcatg gtcgatattg ataatttgta cagcagtcaa
    20701 tgctattgga ttgggtctta taggtgacct tgttgcaaat attcctataa cgtctggtcc
    20761 acttttataa ggttttgggg tttctaaaat acttcttagt tcaggattat caaacccatc
    20821 agcccaccaa aatacattta aatgactgaa atcgtcgagt tcatttaatg caggtacata
    20881 ctttttgtct aatttaataa agacctcttc gccttgaata catattttac ctataggatt
    20941 tattaatatt tctttcataa tattacctcc aactatttaa tttatcattt gtaattttag
    21001 ggtataacat gacatcatgt gagggtcaat ataaaataat aaataaaaat attaatagtt
    21061 agaatgataa tacatttttt acatggagca tgacaccagt aataaggcaa tcttcgtcaa
    21121 tatcaaaagt agaggtatgc aaaggggaag taatgttttt ttcacgattt gcacaaccaa
    21181 ggtggtaaaa agctccttca cagtgtctta gaaaatacga aaagtcttca gcaccaagag
    21241 tgggcgagtc tttaaggata atattttctt caccaaacaa ttctacagca ttttgtttga
    21301 cgtaatctac tagatggttt gaattgataa gagctggata accttcctca atttcaacag
    21361 aaatacttcc tccaaatgtt ttacaagtaa aatcgcaaat ttctctaatt cgtttttttg
    21421 aaaactctct agtttcagga gtcaaggttc tcaaagtacc ccttataacc actttgtcac
    21481 aaactatatt ttctttgatt ccaccttcaa tctttcctag agaaataacc acagaatcag
    21541 ttggatttgt gtttcgacta acgattgtct gtagagctgt aataatatga gcagatataa
    21601 caatagcatc aataccttga tgtggataag ctccatgaca ttttgaacca tgtacagtta
    21661 attgaagtgt attggtggaa gcatttagag tgttgtattt taattcaatt agatttttgt
    21721 tgatattggg atttacatgg agtccaaata tatattttac atttggtttt tcaagacatc
    21781 catcttctat cataagttga gccccaccaa tagtttcctc agcaggttga aaaaagaatt
    21841 ttacatttac atttaagtaa tcctttaatt taaatagtat attacaagta cccagtaaaa
    21901 tagcagtgtg tgcatcatga ccacatgcat gcattttgcc aatattaata gatttataag
    21961 aataattaag ttcttctgtt ataggtaagg catctatatc agctcttata gcaactgttt
    22021 caaagtttgg actcacgtta atgtatgcag ttatccctgt atgattctta tattcaatat
    22081 aatttatacc tatttcattt aagtatttaa taattttttt cttagtttga aattcttcta
    22141 atccaagttc tggagtctta tgtaaatctc ttcttatatt tataacccaa tcatttatct
    22201 catgacaaag agtttttata ttaagcataa aacacatcct aactatatta aaaatttatt
    22261 tttcttcatt aattatatta ttttatgtaa atcattatta tgtatcaagt acaaataaaa
    22321 tatcttataa ttatattaga gatatttagt atggagaaga atatatcatt ttataagaag
    22381 aggtgtttaa atgttaggaa taattgcgcc atctgggcca ttaagaaata caagtttgga
    22441 ggaaataaag tttaatttag aaagttatgg ttacgaagtt aagttttctg aaagttgtag
    22501 tttaaattat aaaggttatt tagctggtaa tgatgatatt agagcaaggg atatagaaga
    22561 tatgttttta gataaagatg tagatataat tatgtgctta agaggaggtt atggaacaac
    22621 aagaatattg gataaaataa attatgatat aataaagcaa aatccaaaac catttatagg
    22681 tttttctgat ataacaggtt taaatttagc tttctataaa aattgtggtc ttttaccata
    22741 tcatggaata atggcagcaa atgtaggtaa atggggtaaa tttacctata aatcattggt
    22801 aaatgcttta gaatttaaag atgaattata tttagaaaat ccaaaagaag aaaagattta
    22861 tactgtatgt gaaggtaaag cagagggaat aataatggga ggaaatttat ccttaataat
    22921 tgccacaatg ggaacaaaat atgaaataga tgcaaaagat aaaattttgt ttattgagga
    22981 aattggagaa cctcaatata aactggatag aatgttaaca caactatatt cttcaggaaa
    23041 acttgaggaa tgtaatggta taatttttgg agattttaag gattgtattg aagaaaatga
    23101 tttgatggaa ttactaatag aatttgcaaa taaggtcaat aaaccttcta tatataatct
    23161 tcagtcagga cattgtatcc caatgataac tattcctttg ggcagaatgt gcgaattaga
    23221 tgctacagaa aaaatcgtta aattaaaaaa atagtgtgta tataaatata atagaaatat
    23281 ggtataatct tatacaagta aaaatttagc taggaggatg aaaaatgtct gatgatagaa
    23341 taatagactt taacgaacta aagaacaaag ttaaagattc tgatgtagat aaatttgagc
    23401 aatacatata taacttatat ttttctgtta tggatggaaa gatgtctatg gctgagtttt
    23461 caagaaaaat attcgattat atgagagata acaacatatc tcaagaaaaa tttatgaaaa
    23521 tacaaaagca atttatggag agatatggta tggacactga agaagtagaa aaacaactta
    23581 gaaactttgg aatcgaccct tctacagcag gttttatgag taataatact tccagcaaag
    23641 tatctacaga agatttagag tcatttaaga agagtgcagg attttatgag aaatatggag
    23701 aaaaaatcca accaaagagt tgtataacaa catttataaa aaatgactta aatgatatta
    23761 atgtaataat cgaccaagaa aagataatgc tttgtagtga tagaaaaata aatcttatgg
    23821 attcagaact aaatgagttt ttattagaat ataagaatat gtttaataaa aaaataaagg
    23881 tagtaatgtg cgaaactacg aataagtatg attattaaaa aatgaattta aatactgaag
    23941 tagtataaat taattgtact acttaaaaat aaaaatcgca atttattatt ccttataaat
    24001 ttgtataagg aatatctaaa ctgcgatttt ttatattgtg aagattagta ataatagata
    24061 gtgttttaaa ttgtaatctt ctcactaaaa ctgtgttttt ctattagaaa ttttattaaa
    24121 aataaatatc tgataattgt attatatggg atgtaaagta ttagaagctt aacgaatctc
    24181 ttttaataca ttaactccat tttgaatcat actgttgaaa aatactaagt ttaaaatctc
    24241 agcagggtga acgttaggaa tatcataagt atctactaaa ttcataggta caactatatt
    24301 tttttcaata ttatgttgat taaaatatga ttttagagtt attgcaaatt gatatataca
    24361 tatatctgtg caatcgccaa ctataattat attatctata ttatcaaaat ccaaattttc
    24421 taatgcaaaa aatccattag tagaattttt aggaagaatt tgtaggtttt ctatcgactt
    24481 aagttcatca accaattcac tttctacatc attttccaaa cagtgaacag gataactcaa
    24541 aagttctatt gatttaggag tatgagaatc agtaaatgct attactctat ttaatttgtt
    24601 tgatattttt tttgtaaaca tttcaattgg ctttattaaa gactctactc taggagagta
    24661 taatgcacct tgtcttgcaa agccattatt aacatcaatt ataaataaag cagttttact
    24721 caaatcataa ttttctattt tttctattgg tagattatct aaattactct ttaaagcttc
    24781 aagttcattt aataagttat ccatagttat acctccaaga taaatttaat aaaattgtac
    24841 atattaatta tataaaagtc aaggagtaca aactattgta taattagctg tattgttttg
    24901 agtgtaaaag atttgaagca atatctggat agttagtaaa aataccatct acattgagtt
    24961 ttagacagtg tagtatatca tcctcttcat ttacagtata tacattgaca ccaagtagat
    25021 ttttgtgaca aagttcaatt agagattcat ttactaaaac tagaggtgga tgaagataac
    25081 tattacccag aaatttagca aaattgacta cattgtttat aggtaaataa cacaataatc
    25141 ctgtttttac actagggtct aatttatgaa agttttttaa gctattgctg ttgaaactag
    25201 atataagaac tctatttttc atattatact ttaaaataag ctctaaaacg cctttttcta
    25261 tattgggata gtttattttg tcagttttta gttcgatatt taaagtaagg tctgtaggtg
    25321 agattagaat taatacttct tctaaagttg gaattttaca ttctttattg ctttgatatc
    25381 cttcaaaaga tgagtttaga gtttttaatt ttcttaaagt aaagtctttt acaaaaccat
    25441 gtccattaaa agttctatca accttttcat catgaataac tacaattttt ccatccttag
    25501 ttctgtggac atcaagttct attccatata tatccatatc caaacatttt ttaaaagcta
    25561 gaatagtatt ttctggatac tttccactaa accccctatg agcataaata ttcatttata
    25621 tggttccctc ctataagtat aacttatctt ataaaaattt aattaatata atatatcata
    25681 tt
//
LOCUS       DAMKNB010000050        24696 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.052, whole genome shotgun sequence.
ACCESSION   DAMKNB010000050 DAMKNB010000000
VERSION     DAMKNB010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 24696)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24696)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24696
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.052"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     regulatory      122..212
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            624..941
                     /gene="flgB"
                     /locus_tag="PC494_002317"
     CDS             624..941
                     /gene="flgB"
                     /locus_tag="PC494_002317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body rod protein FlgB"
                     /protein_id="HDF3912813.1"
                     /translation="MNTYDIIKMGLDATNLRSQTIANNIANINTEGYKRHYITFEETL
                     NDAMPKIEEKTDNSKGLRVDGNNVDIEEEKVNQAMATLQYNALISFANGKIAMTKSII
                     SGR"
     gene            949..1353
                     /gene="flgC"
                     /locus_tag="PC494_002318"
     CDS             949..1353
                     /gene="flgC"
                     /locus_tag="PC494_002318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body rod protein FlgC"
                     /protein_id="HDF3912814.1"
                     /translation="MSVFSGMRISASGLTAESLKMDIISSNVANINATRGPNGEAYRR
                     KVVSFEENYDNKLGMLGVKVTSVEDDKSPLKEVYDPSHPDAKPNGYVEYPNVNILVEM
                     TDLITASRAYDSNVDTLNAQKSMISKALEIGK"
     gene            1363..1680
                     /gene="fliE"
                     /locus_tag="PC494_002319"
     CDS             1363..1680
                     /gene="fliE"
                     /locus_tag="PC494_002319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook-basal body complex protein FliE"
                     /protein_id="HDF3912815.1"
                     /translation="MPITQINNLMQGAKLDNLIGEAKPLTLNNKEEKKNFEDVIIDTI
                     DKVNFQQVTADDMKEKFIKGEDVSMHEVMLIGQEAQLSMQYLIEVRNKIHDAYQEMNK
                     VQI"
     gene            1705..3255
                     /gene="fliF"
                     /locus_tag="PC494_002320"
     CDS             1705..3255
                     /gene="fliF"
                     /locus_tag="PC494_002320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar M-ring protein FliF"
                     /protein_id="HDF3912816.1"
                     /translation="MITSFKNKIKEQVAKSRTKISSLKKGTKIALGIGVIAICLALVF
                     TAISASKNKYAVLFSELDAQDAADISAELESKKIDTKVKGSTIYVPRTEVDKLRLELA
                     PSLTGGSKGFALMDDSSSIGLTDEEFQIKKQRMIQGEIEKTIKSFPQVEDTRVHITFG
                     ESSVFEKEAVPGSAAVYLMLKPGTTLEKNQIKSVMALISGSVTNIPEKNVQVIDNKMN
                     LLSEGILEDENVDENNQPINSGISVDKNKASEQALNKQLEKSILEMLEPIFGKGKVKA
                     TVNADLSFDTAEKTEIKIDPDKVAIKETRSKNSSKSAANNVQGVDANMNNQGNNNGTN
                     TEDSLDESFEYETGKIETHTIVAPGELNRLTASVAIDGKIAKGVQADVEDIVNNAIGM
                     DGARGDTLSVVSMVFDPEGKKEAKQELEEIKKEGFKKNIIKAVIGVVAVIAVGAIGYL
                     IYKKRSEREDMDYEDEDYISKSDSVDRKDNPLLGDDPELTLEEAVKMYAEEKPDQVTE
                     IIKTWLNE"
     gene            3268..4338
                     /gene="fliG"
                     /locus_tag="PC494_002321"
     CDS             3268..4338
                     /gene="fliG"
                     /locus_tag="PC494_002321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor switch protein FliG"
                     /protein_id="HDF3912817.1"
                     /translation="MSTEITNVNAFDLSDINESDKNEKVEGEGLKKAAVLLMTLGPNV
                     SSDIIKSLPDKQVQKIGLEIANISSIASKERREILKEFVEINRAKDYVIEGGLEYARE
                     LLSNALGNVKANKLLEGISINTSTKPFKHIIKLDVKKILEILRNESAQTIAVLLAHME
                     PENGAEVLSYLDFDLQNEVAMRISSMGSISPEVIKVIESSLEDKLHSISGDDFNDYGG
                     VSTLVQILINSDRKTEKNILGTIEEQNPDLAAQIKSHIFVFEDIVKLDDISIQKVLKE
                     VTMKDLVYALKGVDDEISDAIYRNQSSRAADALKEEMEMVGVIKVTQVEASQQKIANI
                     VRKLEREGAITIVRNFGGDFVE"
     gene            4331..5062
                     /locus_tag="PC494_002322"
     CDS             4331..5062
                     /locus_tag="PC494_002322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar assembly protein FliH"
                     /protein_id="HDF3912818.1"
                     /translation="MNNKIIKSKKALYKGVLDLTIIDKVRVGESNVNKENDCRFRDEV
                     IKEAIESAEIKKNEILEEAKINAQNIEKQAYEKGYSQGQKNGYEDGYKESYDEYTQKA
                     KDEADFIKNQANLILLQANEKMTEYIKEKNKEIVRLAINMASSVLKKHFEDEESMSDL
                     LKQIIQDYEGSSSFIVRCNSFYKDNIEKEFELFKEETSLKSSVFVIADDSIDKGNAII
                     QKENGRIIVGIDCAMEKLKEELLGE"
     gene            5066..6385
                     /gene="fliI"
                     /locus_tag="PC494_002323"
     CDS             5066..6385
                     /gene="fliI"
                     /locus_tag="PC494_002323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar protein export ATPase FliI"
                     /protein_id="HDF3912819.1"
                     /translation="MYKTDISIDFDKINKKIENLELTISEGRVKKIIGLTVEVEGIKA
                     FVGELCVIYNQVNKPVNCEVVGFKDKEVILMALGELTLIAPGCKVISKGIPLSVMCSD
                     NLLGKVLDGLGNPIDNSDAVLGDRYNLNNEPPDPMKRKKIRNIMETGVRAIDAFTTCG
                     EGQRIGIFAGSGVGKSTTLGMIARNAKADVNVIALIGERGREVLDFIDKDLGEEGMKK
                     SVVVCATSDKAPLVRLKGALTATAIAEYFRDQGKKVILMMDSVTRFAMAQREVGVAIG
                     EPPAQKGYTPSVFAMLPKLMERTGTSDKGSITAFYTVLVDGDDFNEPIADTTRGILDG
                     HIVLSRDLANKNHYPSIDVLNSLSRLMNEIASKEDIKIASFARDMLAEYREAEDLINI
                     GAYASGTNKKIDEAIYYHEHIINFLKQGINEKSSFNETISSLRRVFE"
     gene            6416..6862
                     /gene="fliJ"
                     /locus_tag="PC494_002324"
     CDS             6416..6862
                     /gene="fliJ"
                     /locus_tag="PC494_002324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012815984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar export protein FliJ"
                     /protein_id="HDF3912820.1"
                     /translation="MELDKNFKFRLQKVLDLKVKDEEEIKMEFAKIQQKKIDIETNLE
                     NLESNYSKYSISKNNDSIQNQKITINYLLALNNSIMDLSEELDKSTNELEKARKQLIS
                     KQIERKSLEKLKEKKYGQYYKEENLKEQNTNDEFASMSYLRNRQVL"
     gene            6891..8096
                     /locus_tag="PC494_002325"
     CDS             6891..8096
                     /locus_tag="PC494_002325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook-length control protein FliK"
                     /protein_id="HDF3912821.1"
                     /translation="MKIQADSYNIIKDIGDRKSSPKNKNIKNNKFEDNLYKATDHKKV
                     KDRREVSKQNISSDKPENSDNECHLDEDKSNHLEDENTYEKDCSKNNEALQQLLNLLK
                     DNYKKDKDINTILNNIEKLSISDELKQELKLNKNILNKIANQNSELNKANINNSNDIE
                     NLDIVKLRELLEDNANKDIEVITKTTENDTKNIDLYSFDSNRMDNLNSNKQKDDSSDI
                     LEKLAGVNGNKSGNFGQVINKNVDMNKIKNDNVNLKQIESNVMDDSIKAIKHMKTNDI
                     QELTIKLRPKELGDMNIQLLKDGESMRAVVTVFNKDVFDSINKNIADLKQHLELTNVN
                     IKDVSVQMHSDNTNTSDTFDKAFEQQNRQNNQENMSKKNTNDKHNNVVIEDDIKENTI
                     DDDRVDLLA"
     gene            8114..8722
                     /locus_tag="PC494_002326"
     CDS             8114..8722
                     /locus_tag="PC494_002326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis protein FlgD"
                     /protein_id="HDF3912822.1"
                     /translation="MYGIATALAGTKGNYRSNNLSQLERNINDIANKQVRSKGNQTVT
                     DNGTPIIGQGDDADKDLFMKILVAQMGNQDPMNPQDPTEYVSQLAQFATLEKMSAMNE
                     KLDVLLALSNSTLINSALSMATSLIGKEVEVSGEEKEDENIVGVVKSTYIKDGEVHLE
                     LEVDGSDKTVGVKYEKLLKIGEVDENSGEENDSSEHESPEEA"
     gene            8749..9732
                     /locus_tag="PC494_002327"
     CDS             8749..9732
                     /locus_tag="PC494_002327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook-basal body complex protein"
                     /protein_id="HDF3912823.1"
                     /translation="MIKAMYSGVSGMKANQTKLDVIGNNVANAGTTSFKKSSARITDS
                     FYQTVLYASAPTAALGGTNLGQVGVGSKISSINKDMVQGNVQPTNRPSDLMIDGDGYL
                     PVVRQGTVMYTRDGSFNLDTGFKAADGALKNIKGGRLVNGDGYMLQGMIYDGEYKADT
                     GEFVKKGDAKGKEPIVIPLQSISPKDGTVQNVLEYNISKDGTVEFLLSDGQRTQFVYD
                     IPDGAKVGDTPAGIDKLKGTIQKVQTYAFQNPAGLDAEGGNLFKPSANSGDPQIAGAT
                     GTIIQGAIEASNVDIAEEFTEMIIASRSFQANSKIISTSDEILQEIINLKR"
     gene            9745..9948
                     /locus_tag="PC494_002328"
     CDS             9745..9948
                     /locus_tag="PC494_002328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar FlbD family protein"
                     /protein_id="HDF3912824.1"
                     /translation="MIRVTDLNGRKYILNSDLIVRIDSVPESRILLTTGEKNLVKESV
                     DEIVDKVIKYKRKINVGYIRSEK"
     gene            9948..10766
                     /locus_tag="PC494_002329"
     CDS             9948..10766
                     /locus_tag="PC494_002329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MotA/TolQ/ExbB proton channel family protein"
                     /protein_id="HDF3912825.1"
                     /translation="MKKTDSLTFIGLIVSTVLVLVGAAKGSSSGLKNFFDVSSILITV
                     LGSFGALMITFTIDDIKLIKNALQYSFKTMSVSKLDLLEQFKTLSKKARKEGLLSIES
                     DVMGIEDPFMKKGLELCIDGLEINEIRSILELEIDSVEDTNNRYSKLFKTWGTFAPAF
                     GMLGTLIGLIQMLADLTSPDLIASGMGKALITTFYGSLLANIALNPIAYNIDEKTEKE
                     IYVKEMMLEGIISIQSGESSIVVEERLATYLSNNEKLEIMKSNKNTERAMSNGA"
     gene            10756..11451
                     /locus_tag="PC494_002330"
     CDS             10756..11451
                     /locus_tag="PC494_002330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OmpA family protein"
                     /protein_id="HDF3912826.1"
                     /translation="MARKKNKKKDEINPDAWLATYADTITLILTFFVLLYATSVVDME
                     KFKNIADALKGQFSGTSIFSTGSSTSEKSPIDSVLVDKNDKSNLEQDLKDKVNNSNLQ
                     NSVTVKDDSRGILLELDDSILFDSGISELKVDSKATLNKVYDMIKMMKNKIVIEGHTD
                     NVPVKSSTHESNWDLSSSRAVSVVRYFVEEKGMDPRLFSATGCGEYQPLVSNETAKGR
                     AENRRVNILITID"
     gene            11463..11906
                     /locus_tag="PC494_002331"
     CDS             11463..11906
                     /locus_tag="PC494_002331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body-associated FliL family
                     protein"
                     /protein_id="HDF3912827.1"
                     /translation="MFKNKKIIIIILILIIFSAGAGFFILGEGGNKQVDKIAGLFIPT
                     GKGKDEVKTENLDLEEMVLKLADEGVRYLKVSITVSYDSSYKDIEKNTPLIRDNIINC
                     FMAKRADDFTADNLKNIKEEIKNTLNIQLGENVIQNIYFTNIVVQ"
     gene            11921..12295
                     /locus_tag="PC494_002332"
     CDS             11921..12295
                     /locus_tag="PC494_002332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis protein FliZ"
                     /protein_id="HDF3912828.1"
                     /translation="MILYLLKILICIPIILILIVLSLKISQGTLLKKYNDKYVKILDI
                     VNISKNNSIIILKIGEEGCIMASSSSSMSKIKDLTKEEILKIENDIKERNFKIQDFKM
                     ERIKKKYDFSRYIGKFTKKEDK"
     gene            12296..12961
                     /gene="fliP"
                     /locus_tag="PC494_002333"
     CDS             12296..12961
                     /gene="fliP"
                     /locus_tag="PC494_002333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425215.1"
                     /note="The bacterial flagellar biogenesis protein FliP
                     forms a type III secretion system (T3SS)-type pore
                     required for flagellar assembly; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar type III secretion system pore protein
                     FliP"
                     /protein_id="HDF3912829.1"
                     /translation="MELLSKLPLADVPYTSSMQLFLFLTALMFLPFVMFMMTSFVRIV
                     ISLSFLKSALGAQQAIPSQILVGLAIVLTIFIMRPVLNEINEKALQPYMKEEVTMEEA
                     MKEAEGPIKEFLLTQTRQTDLDLFVEQAGLKEKKLTRENIPLSVVVPAFAISELKTAF
                     QIGFLIYIPFLIIDLVVASVLMSMGMFMLPPVMISLPFKLLLFVMVDGWNLIVKTLIL
                     GFG"
     gene            12974..13243
                     /gene="fliQ"
                     /locus_tag="PC494_002334"
     CDS             12974..13243
                     /gene="fliQ"
                     /locus_tag="PC494_002334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis protein FliQ"
                     /protein_id="HDF3912830.1"
                     /translation="MSEFMIMSVLKNGMFTGAMIAAPVLIVSLVVGLLISVFQATTQI
                     QEQTLTFVPKLIAILLVVAIGGSWMLHTLISFTSEIFNMISLITK"
     gene            13255..15069
                     /locus_tag="PC494_002335"
     CDS             13255..15069
                     /locus_tag="PC494_002335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fused FliR family export protein/FlhB family
                     type III secretion system protein"
                     /protein_id="HDF3912831.1"
                     /translation="MIFVFIRIVAFFGTLRILFPAGTPALFKSLFAIIISILISSTMQ
                     IEYATNIDNIVLFTLYGINETITGIMLGYITNLCFYSIRMAGSMMDQQMGLSMINMFD
                     PNSMTQTTLIDNLMNWTALMIFFSMDGHHVLIRGIRYSFELIPIGKPFVDNNIDYIIN
                     IFVQCFLTGFKIAIPIVLCLLMADFILGLISRSVPQLNVMIVGMPLKILVGIALFIIS
                     IPLIVNQISHLLSQIPKMYEGTFALAPMFFMGSTDKTEEATPKKKGEQRKKGNIAKSR
                     ELPVAMTLLAFTLLVPTLFSYVVDTLKSSLNYFLSLDFYMNINYSNLEKLVIAGLMDF
                     FKIFLPIAIPFLVLGIIANLFQVGILFTGETLKPNLSKLNPVSGFKNMFSMRSLSTLI
                     KDIAIISILAYIGYTFFQDNYLDILKLGNIYLPTLMYTVKDLVYSILSKICVAMIAIA
                     VADYVYQRYSHKKQLRMTKQEVKDEYKNSEGDPEVKAKIKQKQRQISSQRTMQAVPSA
                     TVIVTNPTHLSIAVRYEKGKDQAPVVVAKGADYLAFKIREIAKGNDIPIIENKPIARL
                     LYKQVEIDQEIPEDMYQAFAEILVAVYKIKNRYKVPKR"
     gene            15078..17153
                     /gene="flhA"
                     /locus_tag="PC494_002336"
     CDS             15078..17153
                     /gene="flhA"
                     /locus_tag="PC494_002336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis protein FlhA"
                     /protein_id="HDF3912832.1"
                     /translation="MNKFNLKENMDVIVAFGVVGIVLMIIVPLPTFILDILLAINISL
                     SVLILLMTLFTTNVLDLSIFPTVLLVTTLFRLGLNLSSTRLILTQGYAGEVIEAFGSF
                     VVGGNYVVGIIIFLIILIVQFVVITNGSGRVSEVTARFTLDAMPGKQMSIDADLNAGV
                     IDDKTARKRRKELQQEADFYGSMDGANKFVKGDAIAGLIVTAINIIGGIVIGAVMLNM
                     TLMGAAQTYVRLTVGDGLVSQIPALLISTSAGIIVTRASTDENFGGLVGKQLTAIPKA
                     VMMTGCVLIVLGMMPGLPKPAFFSLGIGAIAAGYFLGREKKDTLEDLEFEKPDMVNPD
                     KNEVEDVTNLINVESIEVEIGYGLISLADESAGGDLLQRIASIRRQCAIDMGIVVQPI
                     RIRDNLQLNPNQYNIKIKGNVVGGYEIMPNMVLCMDPMNQGFSIFGIKTIEPTFGIEA
                     LWIESDKVEDAELKGYTVVDSSTILITHLLDIIKSNAHELLGRQEVKTIIDAARENYS
                     AVVDELIPDLMTLGEIQKVLKNLLREKVNIKDRVTILETLADQSRNTKDIELLTEYVR
                     IALARSICNNLVDDDKTIVVATLSPETEELISNNLQRSVNGTYPAVDPENTNKIFESI
                     QEVMSNVYFNHNIPVIVVSPKIRAPFRKLVEIVYPNLTVLSLNEIPNDIKIKAEGVVS
                     IYDDEKVYS"
     gene            17128..18144
                     /gene="flhF"
                     /locus_tag="PC494_002337"
     CDS             17128..18144
                     /gene="flhF"
                     /locus_tag="PC494_002337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis protein FlhF"
                     /protein_id="HDF3912833.1"
                     /translation="MMTKKYTANTIQDAMNLAKMELGDNITLIDKKEVRKSGIQGIFS
                     KKDIELTIGWEKRENIEQKDLKREIEQLKLIINNMGFDNKNDNDIDKICKNLLSLELN
                     EEIVESIRIDLQEMKFNGIDTSKNLVEILKKKIKIENQVINGKIALVGPPGVGKTTTI
                     AKLAAKLVFEENKKVGVITIDTYRIGAVEQLKIYTDIMNIPFKGVISPDEMELALDEM
                     KDCDVVLIDTTGRGYKNSMQILEIKNLIDKAETDNIHLVLNCTTRESDTKAIIDSYRN
                     VNFKSLIITKLDETITYGSIFNIMNYAQKPISYITTGQNVPDDIIKPNEDKIIRLLLG
                     VESI"
     gene            18141..19019
                     /locus_tag="PC494_002338"
     CDS             18141..19019
                     /locus_tag="PC494_002338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MinD/ParA family protein"
                     /protein_id="HDF3912834.1"
                     /translation="MIDQAQILRKMAMEKRGLDEFIVENENVPKIITIASGKGGVGKS
                     NLATNLSICLTKLNKKVLILDADIGMSNIDIIMGVNVKGTIIDVINGEKNIEDIISQT
                     KYGVNIISGGSALNHIEDFTEAQRNKFIHSIEQIHDVDFIIIDTGAGMSKSLLSFIYC
                     STEFFLITTPEPTSLTDAYSLLKAISNFGIKRSANIIINRVIDLEEAKSTYKRIKMVV
                     DKFLNLNLELYGYIIDDKKVSLCVKKQIPFILEYPTSIASKCIIAIAKRMVSQSREDI
                     VDNKSFLRKMFSIFKS"
     gene            19033..19734
                     /locus_tag="PC494_002339"
     CDS             19033..19734
                     /locus_tag="PC494_002339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FliA/WhiG family RNA polymerase sigma factor"
                     /protein_id="HDF3912835.1"
                     /translation="MNREELIKENMPLVKSIARKFFIPGKGFEYQDLVNSGVIGLIDA
                     INKFDAEKGAKFSSYSYIKIKSAILDEIRNQSPISKHNLTKVNKYNRVVEKLQSKLLR
                     EPTSYEIAKELKVSEKELHDIESNIDMLNIVSLNYVIFEDTNETVQDVISDREEEAPE
                     NIIEEEEKLEILSKAISNLNEREKLILSLYYYEDLNLKEIGKVLGVSESRVSQLHRKS
                     IRNLRNKIKELKYSI"
     gene            19750..20172
                     /locus_tag="PC494_002340"
     CDS             19750..20172
                     /locus_tag="PC494_002340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar protein"
                     /protein_id="HDF3912836.1"
                     /translation="MIQIILIVVSILIIVTIVINLHKESKNKDNRYFDKIFEQEYEAN
                     DRLIIAEKRRFFLDKVLAEKRINSHIKVYENYNLIKANEERKENIFIESKKEVRQENE
                     LSLKVKHLISSGYDDVEICKMLDIGKGELLLIRSCYKI"
     gene            20157..20342
                     /locus_tag="PC494_002341"
     CDS             20157..20342
                     /locus_tag="PC494_002341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar protein"
                     /protein_id="HDF3912837.1"
                     /translation="MLQNIRILLCDKKVFLGIGIGILISTLCIMLFSNNDMSKAEIEK
                     KARALGMKYTSEMKVLE"
     gene            20383..21156
                     /gene="flgG"
                     /locus_tag="PC494_002342"
     CDS             20383..21156
                     /gene="flgG"
                     /locus_tag="PC494_002342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body rod protein FlgG"
                     /protein_id="HDF3912838.1"
                     /translation="MIRGLYTAVSAMITNQQKQNVVVNNLANMDTNGYKSKQLLTKSF
                     DELKLEGYNNYANGTKQKQIIGDISPGISMDETITNFNQGPIKTTDNKMDVAIQGKGF
                     FLVSDAAGNQFYTRNGNFRTDNQGDLITSEGYYVLGTNTATGAVGHINVGNQKFEVAK
                     DNTISLDGNAMYKFNIVDFNNYNNLKKEGDNLYSGGGAMKVNNALTIQSAIESSNVDM
                     VSEINNMMTISREYEANQKIIQAMDSKLAKIASEIGSVR"
     gene            21177..21938
                     /gene="flgG"
                     /locus_tag="PC494_002343"
     CDS             21177..21938
                     /gene="flgG"
                     /locus_tag="PC494_002343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body rod protein FlgG"
                     /protein_id="HDF3912839.1"
                     /translation="MYTMFYTSKTALSANQSKLDIISNNIANSDSTGYKKINMEYSDL
                     VDEVLNRPSYPTNGNDISTGTGAKATAPMRNYEQGALAPTDSKSNLAIDGEGFFRVIR
                     KDGTYAYTRNGGFNVDALGKIVDDNGNILDVQFDAGYNYNNTNIDSTNLTVSRNGELF
                     VDNKKIGKINLYQPIGTQNFISEGDSLFVATDAAQIKQVEKVDIVQGYRERSNVSLQE
                     EFVDLIATQRAFQMNSKGIKTADEMWQIANNLRAK"
     gene            21961..22842
                     /locus_tag="PC494_002344"
     CDS             21961..22842
                     /locus_tag="PC494_002344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FliM/FliN family flagellar motor switch protein"
                     /protein_id="HDF3912840.1"
                     /translation="MNDMKEYDFGKPQSYSRENLTCLNFLLAEFCKKYKNYIIYELKC
                     NSSMVVDSIDQVNYQTFLDRVTSSCVVVQNAMEPVMKNFSFRIDRSVADMWIDITSGG
                     TGVVKDNDRELTELDKKVLLHLMDDLVRNMHLFEGFENIQVLDTHTHINLPQLCSPTA
                     PVCVVDLKVLNDNEYIGSVSLCFPYNGLEALLESISVIEFFDNDVGDDSEEFTQKIYN
                     SVSNIELSVIAEIGKVSINVEDLLKLEVGDVIVTNKKINDYIDIFVENSKSYTATPGF
                     ISSKKGVKINDAVGKEV"
     gene            22845..23219
                     /locus_tag="PC494_002345"
     CDS             22845..23219
                     /locus_tag="PC494_002345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FliM/FliN family flagellar motor switch protein"
                     /protein_id="HDF3912841.1"
                     /translation="MDNSNLISDEEAKMLLNDKVESEVDGDDELALDVSEVNRNNIQR
                     ILDLKLELSVVIGRTKMTLRDILNLHKGSLIELDTLADQDVEILIDNKVLAYGKVVVV
                     DLNFGVKITSIVSEEDMVKSLV"
     gene            23251..24654
                     /locus_tag="PC494_002346"
     CDS             23251..24654
                     /locus_tag="PC494_002346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HDF3912842.1"
                     /translation="MVLILNLNDIKKDILKLNKKDSCSLYNESINNINNNCISTGLKF
                     LKQARDLNPDDVDILNLTGLVNLLKCNFDDAVESFYKSSLCEKTALCEKYINMLTSEE
                     FLIFFEKYNQLIRLINKGMYKEAIQGFKLITDQYCDLIEPYELLALLYDKEEEYIKFD
                     ECLEVLKIIDKENYLLNQENNTLYMYNSANIQTKSNIKVDDYKNEFLHKSSSNHKIND
                     YNDVTKEKSSSKNQKSSDSNKKKSIKKNKYLYIAIILGILLVGQSIYSSYKMNNLTDK
                     ISKNNETKNEESIDSNLTKKENNIEENEDMSKASNINKSNKNINKEDDVKSKKNTVEN
                     EDDKDSDLFTEDELMSKANTLKSEKKTKSSIQLYKKVADIGENKGNTSEATYQVAILS
                     EKLKDYKTAEEYYKMYVENYSEKDAYFDESYYNLGMMYYNNGDLKNSKLTLKKLVNKV
                     PNSMYNNSKVKEILKEE"
BASE COUNT        10216 a         2631 c         4613 g         7236 t
ORIGIN      
        1 ttgtaaacta tagtgtttat aatctttgta attattggta attaaattta aaaaataaaa
       61 tatttaatta tacacaaaaa agatatttaa aaaatttgtt atttattgta tacttaagtt
      121 aaaactaaat aggcaaatct agagaaatct agtgacgcaa agctataggg actaaggttt
      181 atatacataa actatgtcag ccagttgcca aaaagagtcc taggtgtatt gtatacctaa
      241 gaaaagtcta taatgactgc ctttttggca gtcattttgt tatggaaaaa tcactttatt
      301 tcagtagaaa atacacataa taacatattt taccaattat aacataaaat aaagaaaaat
      361 tatctcaaaa agttactatt ttacaaaaaa aaatgacttc tttatttatt taaattaatc
      421 gcatttccat tacattaata caataatgta tcaatttagt aagaaaacta atattttttt
      481 aatgaagtcc catgaaaata taaaaaaatt ttaatatgta tttaaatatt tcttcgaaaa
      541 gttgctcttt tttgtaatat agcaacttca ttttttttat taataaacaa aatagataaa
      601 atatattttg aggaggggtg agtgtgaata catatgacat tataaaaatg ggattagatg
      661 caactaatct aagaagtcag acaatagcaa ataatatagc aaatataaat actgaaggat
      721 ataaaagaca ttatataact tttgaagaaa cactaaatga tgctatgcct aaaatagaag
      781 aaaaaacaga caattctaaa ggtttaagag tagatggtaa taatgtagac atagaagaag
      841 aaaaagtaaa tcaagcaatg gcaacattac aatataatgc tttgataagt tttgcaaatg
      901 gaaaaatagc aatgaccaaa tcaataataa gtgggaggta attagaagat gagtgtgttc
      961 agtggaatga gaatatctgc tagtggatta acagcagaaa gtttgaaaat ggatatcata
     1021 tcatccaatg tagctaatat aaatgctaca agaggtccaa atggagaagc atataggaga
     1081 aaagttgttt catttgaaga aaactatgat aataaattag gtatgctagg agtaaaagtt
     1141 acatctgttg aagatgataa atcacctctt aaagaagtat atgacccatc tcatccagat
     1201 gcaaagccaa atggatatgt agaatatcca aatgtaaata tattggtaga aatgacagat
     1261 ttaataacag cttcacgagc atatgattct aacgtagata cattgaatgc tcagaagtct
     1321 atgatatcaa aagctttgga aataggaaag tagggataaa ttatgccaat tacacaaatt
     1381 aacaatttaa tgcaaggtgc aaagttagat aatttgattg gagaagcaaa gccattaact
     1441 cttaataata aagaagaaaa aaagaatttt gaagatgtaa taatagatac tatagataaa
     1501 gttaattttc aacaagtaac agcagatgat atgaaagaaa aatttataaa aggcgaagat
     1561 gtttctatgc atgaagttat gttaataggt caagaagcac aactatctat gcaatattta
     1621 atagaagtta gaaataagat tcatgatgca tatcaagaaa tgaataaggt gcaaatttag
     1681 ccttttgaac aggagtaata atcaatgata accagtttta aaaataagat taaggagcaa
     1741 gttgctaaat ctaggacaaa gataagttct ttaaaaaagg gaactaaaat agcattaggt
     1801 ataggggtta ttgctatatg tttagcgcta gtatttacag caatatctgc gagcaaaaat
     1861 aagtatgcag tcttattttc agaactagat gctcaagatg ctgcagatat atcagcagag
     1921 ctagagtcta aaaagataga tactaaggta aaaggaagta cgatttatgt acctagaaca
     1981 gaagttgata agttaaggct ggagttagcg ccaagtctta caggtggttc taaaggattt
     2041 gcactaatgg atgatagttc atcaataggg cttactgatg aagaatttca gattaagaaa
     2101 caaagaatga tacaaggtga aatagaaaaa acaataaaga gttttccaca agtggaagac
     2161 actagagtac atataacatt tggagagtca tcagtatttg agaaggaggc tgttccaggg
     2221 agtgcagcag tttatttgat gctaaaacca gggacgactt tagaaaaaaa ccaaataaag
     2281 tctgttatgg cacttatatc aggaagcgtt acaaatatac cagagaaaaa tgttcaggtt
     2341 attgataaca aaatgaattt attatctgaa ggtattttgg aggatgaaaa tgttgatgaa
     2401 aataatcaac caataaatag tggcattagt gttgataaaa ataaggcatc tgaacaagca
     2461 ttgaataaac aactagaaaa gtctatttta gaaatgctag aaccgatatt tggtaaggga
     2521 aaggtgaaag ctacagtaaa tgctgattta agttttgata cagctgaaaa aactgagata
     2581 aaaattgacc ctgataaagt tgcaataaag gagacaaggt cgaaaaattc atctaaatct
     2641 gctgcaaata atgttcaagg tgtagatgct aacatgaata accaaggaaa taacaatggt
     2701 actaatacag aagatagttt agatgagagt tttgagtatg aaacaggtaa gattgaaact
     2761 cacactatag ttgcgcctgg agaacttaat agattgacag cttctgttgc aatagatgga
     2821 aaaatagcta aaggtgttca agctgatgta gaggatattg ttaataatgc tataggtatg
     2881 gatggagcga ggggagatac tcttagcgtt gtttcaatgg tatttgaccc agaaggtaag
     2941 aaagaggcta aacaagagct ggaagagatt aaaaaagaag gatttaaaaa gaacataata
     3001 aaagcagtta ttggagtagt agcagtaata gcagttggag ctattggata cttaatatat
     3061 aagaaaagaa gtgaacgaga agatatggat tatgaagatg aagattatat ttctaaatct
     3121 gattctgttg ataggaagga taatcctcta ttaggagatg atccagaact gacattagag
     3181 gaagctgtta aaatgtatgc agaagaaaag ccagaccaag taacagagat aataaagact
     3241 tggttaaatg agtaaggggg atagaaagtg tccacggaaa ttacaaatgt taatgcgttt
     3301 gacttaagtg atataaatga aagtgataag aatgagaagg tagaaggtga gggtttaaaa
     3361 aaagctgctg tattattaat gacattaggc ccaaatgtgt ctagtgatat aataaaaagc
     3421 ttgcctgata aacaagttca aaaaataggt ttggaaattg caaatatttc ttcaatagct
     3481 tcaaaagaaa gaagagaaat cttaaaagag tttgtagaaa taaatagggc aaaagattat
     3541 gttatagaag gtgggcttga atatgcaaga gagttattaa gtaatgcttt aggaaatgtt
     3601 aaagcaaaca aattacttga aggtatatca ataaatacaa gtacaaagcc ttttaaacat
     3661 attataaaac tagatgtaaa gaagatatta gaaatactta ggaatgaaag tgcacaaact
     3721 atagccgttt tacttgcaca tatggaacca gaaaatggag cagaagtttt atcatactta
     3781 gattttgatt tacaaaatga agtagctatg agaataagct caatgggttc aatatctcca
     3841 gaagtaataa aggtaattga aagttcatta gaagataaat tacattcaat aagtggtgat
     3901 gattttaatg attatggagg ggtgtctacc ttagttcaaa tattgattaa ttctgataga
     3961 aaaacagaaa agaatatttt gggaactatt gaagaacaaa acccggattt agcagctcaa
     4021 attaaatctc atatatttgt ctttgaagat attgtcaagt tagatgatat aagcatacaa
     4081 aaagtgttaa aagaagtgac tatgaaagat ttagtatatg ccttaaaagg tgtagatgat
     4141 gagatttcag atgctatata tagaaatcaa tcttctagag cagcagatgc acttaaagaa
     4201 gaaatggaaa tggttggtgt tataaaggtt acacaagttg aggcttctca acaaaagata
     4261 gctaatatcg taagaaaact tgaaagagaa ggtgccataa ctattgtaag gaattttggt
     4321 ggtgactttg ttgaataata agattattaa aagtaaaaaa gcattatata aaggagtgct
     4381 agatttaacc ataatagata aagttagagt gggagaatca aatgtaaata aagaaaatga
     4441 ttgtagattt agggatgagg taataaaaga agctatagaa tctgctgaga taaaaaagaa
     4501 tgagatatta gaagaagcaa aaataaatgc acaaaatata gaaaagcaag catatgaaaa
     4561 agggtatagt caaggtcaaa aaaatggata tgaggatgga tataaagagt catatgatga
     4621 atatacccaa aaagctaaag atgaagcaga ttttataaaa aatcaggcaa atttaatctt
     4681 attacaagct aatgagaaga tgactgagta cataaaagaa aaaaataaag agattgtaag
     4741 acttgctatt aatatggcca gttctgtttt aaaaaagcat ttcgaagatg aagaatctat
     4801 gagtgatctg ttaaagcaaa ttattcaaga ttatgaagga agtagttcat ttatagtaag
     4861 atgtaattct ttctataaag ataatataga gaaagagttt gaattattca aagaggaaac
     4921 atcactaaaa tcaagtgtat ttgttattgc agatgatagt atagataaag gcaatgctat
     4981 tatccaaaag gaaaatggaa gaataatagt tggtattgat tgtgctatgg aaaaactaaa
     5041 agaagaattg cttggtgaat aaagtatgta taaaactgat atatctatag attttgacaa
     5101 aataaataag aaaatagaaa atttagaact cactatatca gaaggtagag taaagaagat
     5161 aataggactt actgtagaag ttgaaggaat aaaagctttt gttggggagt tatgcgttat
     5221 atacaaccaa gttaataaac cagtgaattg tgaagtagta ggttttaaag ataaagaagt
     5281 catattaatg gcgttgggag aattaacatt gatagcacct ggttgtaaag ttatttctaa
     5341 ggggatacct ttaagtgtta tgtgtagtga taatttacta ggtaaagtac ttgatggtct
     5401 tggaaatcct atagacaact cagatgctgt tttaggagat agatacaacc tgaacaatga
     5461 acctcctgat ccaatgaaga gaaaaaagat acgaaatata atggaaacag gtgtaagagc
     5521 aatagatgca tttactactt gtggtgaagg acagagaatc ggcatatttg caggaagtgg
     5581 agtaggtaag agtacgactc taggtatgat tgctaggaat gcaaaagcag atgtaaatgt
     5641 aattgctctt attggagaaa gaggaagaga agtactagat tttattgata aagatttagg
     5701 tgaagaggga atgaaaaaat ctgttgttgt gtgtgcaaca tcagataaag cccctctagt
     5761 taggttaaaa ggtgctctta ctgctactgc aatagcagaa tattttagag accaaggcaa
     5821 aaaagtaata cttatgatgg attcagtaac tagatttgct atggcacaaa gagaagttgg
     5881 tgtagcaata ggagagccac cagctcaaaa aggatataca ccatctgtat ttgcaatgtt
     5941 gccaaaactt atggagagaa cagggacatc agataaaggt tctataactg cattttatac
     6001 agtattagtt gatggagatg actttaatga gccaatagca gatacaacaa gagggatact
     6061 tgatggtcat atagttttat ctagagactt ggcaaataag aatcactatc cttctataga
     6121 tgtattaaac agtttaagta ggcttatgaa tgaaattgct tcaaaagaag acataaaaat
     6181 agcgtctttt gcaagagaca tgcttgctga gtatagagaa gcagaagatt tgataaatat
     6241 aggtgcatat gcttcaggta caaataaaaa aatagatgaa gcaatctatt atcatgagca
     6301 tattattaat tttttaaaac aagggataaa tgaaaagagt tcttttaatg aaactataag
     6361 tagtttgaga agagtttttg aataaacaat taaaaaaata tttgaatagg ttgtgatgga
     6421 attggataaa aactttaagt ttagattaca gaaagtttta gacttaaaag tgaaagatga
     6481 agaagagata aaaatggaat ttgctaagat tcaacaaaaa aaaatagata tagagactaa
     6541 tttagaaaac ttagaaagta attatagcaa atattctata agtaaaaata acgatagtat
     6601 tcaaaatcaa aaaataacta ttaactattt actagcttta aacaattcta taatggattt
     6661 atcagaagag ttggataagt caacaaatga acttgaaaaa gctagaaagc agcttataag
     6721 caaacagata gagagaaaat cattagaaaa attaaaagaa aaaaagtatg gacagtatta
     6781 taaagaagaa aatttaaaag aacaaaacac taatgatgag tttgcaagta tgagttattt
     6841 aaggaataga caagttctat aagaatagta ggaagtgagg atattattgt atgaagatac
     6901 aagcagattc ttataatatt attaaagata ttggggatag aaaaagttca cctaagaaca
     6961 aaaatataaa aaataataaa tttgaagata atctatataa ggcaacagac cataaaaaag
     7021 ttaaagatag aagggaagta agtaagcaaa atattagctc agataaaccg gaaaatagtg
     7081 ataatgagtg tcatttagat gaagataaaa gtaatcactt agaagatgaa aatacatatg
     7141 aaaaagattg tagtaagaat aatgaagctt tgcagcaatt actgaatctt ttaaaggata
     7201 attataaaaa agataaagat ataaacacta tattgaataa tatagaaaaa ctaagtatat
     7261 cagatgaatt aaaacaagaa cttaagctta ataaaaatat attaaataag attgcaaatc
     7321 aaaattcaga gctaaataaa gctaatataa ataactctaa tgatatagaa aatttagaca
     7381 tagttaaatt aagagaactt ttggaagata atgctaataa agatattgaa gtaattacta
     7441 aaactacaga aaatgatacc aaaaatatag atttgtatag ttttgatagc aatagaatgg
     7501 ataatcttaa ctcaaataaa cagaaagatg atagctctga tattttggaa aaactagcag
     7561 gggtaaatgg aaataagagt gggaattttg gacaagtaat aaataaaaat gttgatatga
     7621 ataaaattaa aaatgataat gtcaatttaa aacagataga atcaaatgta atggatgact
     7681 ctataaaagc tattaagcat atgaaaacaa atgatataca agaattgaca attaaattaa
     7741 gaccaaaaga attaggagat atgaatatac aattgttaaa agatggtgaa agtatgagag
     7801 ctgttgtgac tgttttcaat aaagatgtct ttgactctat aaataaaaac atagcagatt
     7861 taaagcaaca tcttgaactt actaatgtaa atataaaaga tgtatcagtg caaatgcaca
     7921 gcgataatac aaatacatct gatacctttg ataaagcatt tgaacaacag aatagacaaa
     7981 ataaccaaga aaacatgagt aagaagaata caaatgataa gcataataat gtagtcatag
     8041 aagatgacat taaagaaaat actattgatg atgatagagt agatttacta gcttagtaag
     8101 ggggaagtat tgcatgtacg gaatagcaac ggctttggca ggaactaagg gaaactatag
     8161 gtcaaataac ttaagccaac ttgaaagaaa tattaatgat attgccaata aacaagttag
     8221 aagcaaagga aatcagacag taacagacaa tgggactcca attataggac aaggtgatga
     8281 tgctgataaa gacttgttta tgaagatact tgtggcacag atgggtaatc aagacccaat
     8341 gaatccgcaa gacccaacag aatatgtgtc acaattagca cagtttgcaa ctttagaaaa
     8401 gatgtcagct atgaatgaga agctagatgt acttttagcc ttaagtaatt ccactctaat
     8461 aaactctgct ttaagtatgg caacatcatt aattggtaaa gaagtagaag tatctgggga
     8521 agagaaagaa gatgaaaaca ttgtaggagt agtaaagtcc acatatataa aagatgggga
     8581 agtacactta gaattagaag tagatggaag tgacaaaact gtaggtgtta aatatgaaaa
     8641 attacttaaa ataggagagg tagatgaaaa ttcaggagaa gaaaatgatt cttcagaaca
     8701 cgaatctcca gaagaagcat aatattaaat gagaaaagag gtaaattcat gataaaagca
     8761 atgtattcag gtgtaagtgg aatgaaagca aatcaaacaa aattagatgt aataggtaac
     8821 aatgtagcca acgctggaac tacttctttt aagaaaagtt cagctagaat aacagattca
     8881 ttttatcaaa ctgtactata tgcaagtgct ccaacagctg cattaggagg aacaaactta
     8941 ggacaagtag gtgtaggtag taagatatca agtataaata aagatatggt acaaggaaat
     9001 gtacaaccaa ctaatagacc atctgattta atgatagatg gagatggata tcttccagta
     9061 gtaagacaag gaacagttat gtatacgaga gatggttctt ttaatttaga tacaggattt
     9121 aaagcagctg atggtgcttt gaagaatatt aaaggtggaa gacttgtaaa tggtgatgga
     9181 tatatgttac aaggtatgat ttatgatggg gaatataaag ctgatactgg agaatttgtt
     9241 aaaaagggtg atgctaaagg aaaagagcct attgtaatac cacttcaaag tataagtcct
     9301 aaggatggaa cagttcaaaa tgtactagag tataatatat caaaggatgg aacagtagaa
     9361 tttttattga gtgatggtca aagaactcaa tttgtctatg atatacctga tggtgctaag
     9421 gtaggagata cacctgctgg aatagataaa ttaaaaggta caatacaaaa agtgcaaaca
     9481 tatgcattcc aaaatccagc aggactagat gcagaaggag gaaacttgtt taaaccatca
     9541 gcaaactcag gagacccaca aatagcagga gctacaggaa caataataca aggggcaata
     9601 gaagcttcca atgtagatat agcagaagaa tttacagaaa tgataatagc aagtaggtct
     9661 ttccaagcaa acagtaaaat aatatcgaca tcagacgaga tacttcaaga aataataaat
     9721 cttaagagat agtaggtaca tattatgata agagtaacgg atttaaacgg aagaaaatac
     9781 atattaaatt cagaccttat agtgaggatt gattctgtac cagaaagtag gattctcctt
     9841 acaacaggag aaaaaaacct tgtaaaagag tcggtagatg agatagtaga taaagtaata
     9901 aagtataaaa gaaaaataaa tgtaggttat attaggagcg aaaaataatg aaaaaaacag
     9961 attcactgac atttattgga ctaatagtat ctacagtatt agttttagtt ggtgccgcaa
    10021 aaggaagtag ttcagggtta aagaattttt ttgatgtttc atcaatatta atcacagtgc
    10081 ttggttcatt tggagctcta atgattacat ttactataga tgatataaaa cttataaaaa
    10141 atgcattaca atactcattt aagacaatga gtgtatcaaa gttagattta ctagaacaat
    10201 ttaaaacact ttctaaaaaa gctagaaaag aaggtctttt atcaatagag agtgatgtaa
    10261 tgggaataga agatccattt atgaagaaag ggttagagct gtgtattgat ggattggaaa
    10321 tcaatgagat aaggtccatc ttagaactag agatagattc tgttgaagat acaaataaca
    10381 gatactctaa actatttaaa acttggggaa cctttgcacc tgcttttggg atgttgggaa
    10441 cactaatagg tttaatacaa atgttagctg accttacatc tccagattta atagcatctg
    10501 gcatgggaaa ggcattaatt acaacgtttt atggttcttt acttgccaat atcgctttga
    10561 acccaattgc atataatata gatgagaaga ctgaaaaaga aatttatgta aaggaaatga
    10621 tgttggaagg tataataagc atacaatctg gggagagcag tatagtagtt gaggaacgtt
    10681 tagccacata cctttcaaac aatgagaagt tagaaattat gaaatccaat aaaaatacag
    10741 aaagagcaat gagcaatggc gcgtaaaaaa aataagaaaa aggatgagat aaatccagat
    10801 gcatggctgg ctacttatgc agatactata acactgattc ttacattttt cgtattattg
    10861 tatgcaacat cagttgtaga tatggaaaaa tttaaaaaca tagcagatgc gttaaaaggt
    10921 cagttttctg ggacaagtat atttagtacg ggttcaagta caagtgagaa atctccaata
    10981 gacagtgttt tagtggataa aaatgataaa tcaaatttag aacaggattt aaaagataaa
    11041 gttaataatt ctaacttaca aaatagtgta acagtcaaag atgatagtag agggatttta
    11101 ctagagttag atgattcaat tttatttgac tctgggattt ctgagttaaa agtagatagt
    11161 aaagctactc ttaataaagt atatgacatg ataaagatga tgaaaaataa gatagttata
    11221 gaaggccata ctgataatgt acctgtaaaa tcaagtacac atgaatccaa ttgggattta
    11281 tcttctagta gagcagtaag tgttgtaaga tactttgtag aagaaaaggg catggaccct
    11341 agactatttt cggcaacagg atgtggagag tatcaacctt tggtttcaaa tgaaacagca
    11401 aagggaaggg ctgagaatag aagagttaat atacttataa ctattgacta ggaggaagag
    11461 gtttgttcaa aaataaaaaa attattataa ttattttgat actgattatt ttctcagcgg
    11521 gagcaggttt ttttatatta ggagaaggtg gaaataaaca agttgacaag attgcaggtt
    11581 tgtttattcc aacaggaaaa ggtaaagatg aagtaaagac cgaaaatctt gacttagaag
    11641 agatggtatt aaagctagct gatgaaggtg taagatattt aaaagtatca ataactgtat
    11701 cttatgattc ttcatataaa gatatagaaa aaaatacgcc tttaattagg gataatatta
    11761 taaattgttt tatggcaaaa agggcagatg attttactgc tgataattta aagaacataa
    11821 aagaagaaat taaaaataca ttaaatatac aactaggtga aaatgtaatt caaaatatat
    11881 atttcacaaa tatagtagtg caataaaagg atggtaagac atgatacttt atttactaaa
    11941 aatattaata tgtatcccaa taattttaat attgatagtc ttatctttaa aaattagcca
    12001 aggaacttta ttaaaaaaat ataatgataa atatgtaaaa atactagata ttgtaaatat
    12061 aagtaaaaac aatagcataa taattttaaa aataggtgaa gaaggatgca ttatggcatc
    12121 ttcttcttct agcatgagta aaataaaaga tttgaccaaa gaagaaatat taaaaataga
    12181 aaacgacatt aaagaaagaa attttaaaat tcaagatttt aaaatggaaa gaattaaaaa
    12241 gaaatatgat ttcagtagat atattggaaa atttacaaaa aaggaagata agtaaatgga
    12301 actattatca aaattacctt tggctgatgt accatataca agttcaatgc aattgttttt
    12361 atttctaact gcattaatgt ttttaccatt tgtaatgttc atgatgacaa gctttgtcag
    12421 aatagttata agtttatcat ttttgaaatc agcattagga gcacagcaag caattccaag
    12481 tcaaattttg gtaggacttg caatagtatt gacaatattt ataatgagac cagtattaaa
    12541 tgagataaac gaaaaggcat tacaaccata tatgaaagaa gaagttacta tggaagaagc
    12601 tatgaaggaa gcagaaggac ctattaaaga gtttttatta acacaaacca gacagacaga
    12661 tttagattta tttgtagaac aggctggttt aaaagaaaag aaattaactc gtgaaaatat
    12721 accactatct gttgtagttc cagcatttgc tataagcgaa ctaaaaactg cttttcaaat
    12781 aggtttttta atatatatac catttttgat aatagacctt gttgtggcaa gtgttttgat
    12841 gtctatgggt atgtttatgt tgcctccagt catgatatca ttaccattta agttattatt
    12901 atttgtaatg gtggatggat ggaacttgat agtaaaaaca ttgatattgg gatttggata
    12961 ggagaaaaat agtatgagtg aatttatgat aatgagtgtt cttaaaaatg gcatgtttac
    13021 aggagctatg attgcagctc cagtactcat tgtttctctt gtagttgggc ttttaataag
    13081 tgtgtttcaa gctacaactc aaatccagga gcaaactttg acttttgtac caaaactaat
    13141 agctattctt ttagtagtag ctattggtgg aagctggatg ttacatactc ttattagctt
    13201 tacttctgag atattcaata tgatatctct tataactaaa taagtaggat acatatgatt
    13261 tttgtattta ttagaatagt agcattcttt ggaacattaa gaatactatt tccagctggt
    13321 acacctgctt tatttaagtc actctttgca atcattatat caatattgat ttcaagtact
    13381 atgcaaattg aatatgcaac aaatatagac aacattgtat tgtttacctt atatggtata
    13441 aatgagacca taactgggat tatgcttgga tatataacca acctatgttt ttatagtatc
    13501 agaatggcgg gttctatgat ggaccaacag atgggattat caatgattaa tatgtttgac
    13561 ccaaattcaa tgactcagac aactttaatt gataatctta tgaactggac agcacttatg
    13621 atatttttta gcatggatgg tcatcatgtt ttaattagag gtataaggta tagttttgag
    13681 ttaattccaa taggaaaacc atttgtagat aataacatag attatataat aaacatattt
    13741 gtgcagtgct ttttaactgg attcaaaata gcaataccta ttgtactttg tctgcttatg
    13801 gcagatttta ttttagggct tatatcaaga agtgtacctc aattaaatgt aatgatagtt
    13861 ggtatgccat taaaaatatt ggttggtatt gcattattta tcatatcaat acctttaatt
    13921 gtcaatcaaa taagtcattt attaagtcaa ataccaaaga tgtatgaggg aacttttgca
    13981 ctagctccta tgttttttat gggttcaaca gataaaacag aagaagctac tccaaagaaa
    14041 aagggagaac aaagaaagaa aggtaatata gcaaagagta gagaattacc cgttgcaatg
    14101 actctacttg cattcacctt attagtacct acattatttt catatgtagt agatacactt
    14161 aaatcttcgc ttaattattt tttgagtcta gatttttata tgaacataaa ttattcaaac
    14221 ctagagaaat tagttatagc aggattaatg gattttttta agatattttt accaatagct
    14281 attccctttt tagttttagg cataatagca aacctatttc aggtgggaat actgtttact
    14341 ggtgaaactt taaaaccaaa tttatcaaaa ttaaatccag ttagtggatt caaaaacatg
    14401 ttttctatga gaagtttgtc aaccttaata aaggatatag caattatatc tattttggct
    14461 tatataggat atacattctt ccaagataat tatttagata tattaaagct aggtaacata
    14521 tacctaccaa ctttaatgta cacagttaaa gatttagtat attcaatatt gagtaagatt
    14581 tgtgtagcta tgatagctat agcagttgca gattatgttt atcaaagata cagtcataaa
    14641 aagcaactga gaatgacaaa acaagaagtt aaagatgaat ataaaaactc agaaggagac
    14701 ccagaagtaa aagctaagat aaaacaaaaa caaagacaaa tttcgtctca aaggacaatg
    14761 caagcagtac caagtgctac tgtaatagta accaatccaa cccacttatc tatagcagtg
    14821 agatatgaaa aagggaaaga ccaagctcca gtagtggtgg caaaaggtgc agattattta
    14881 gcttttaaaa taagggaaat tgcaaaggga aatgacatcc ctataataga aaacaaacct
    14941 attgctaggt tgttatataa gcaagtagaa atagaccaag aaattccaga ggacatgtat
    15001 caagcttttg cagagatatt agtggcagta tataaaatca aaaatagata caaagtcccc
    15061 aaaaggtagg ataagtaatg aataagttta atttaaagga aaatatggac gtaatagtgg
    15121 catttggtgt tgtagggatt gttcttatga taatagtgcc attacctaca tttatattag
    15181 atattttact ggcaattaac ataagtttat ctgtgctaat tttactaatg acattattta
    15241 caacaaatgt acttgattta tctatatttc caacagtgtt acttgtgaca acactattta
    15301 gattgggatt aaatctttca tcaactagat tgattttaac acagggatat gcaggtgaag
    15361 ttatagaggc atttggaagt tttgttgtag gtggaaatta cgtagtaggg ataattatat
    15421 tcttaattat attaattgtt caatttgttg ttataaccaa tggttctgga agagtatccg
    15481 aagtaacagc tagatttaca ttagatgcta tgccaggtaa gcagatgagt atagatgcag
    15541 atttaaatgc aggagttata gatgacaaaa ctgctagaaa aagaagaaaa gagcttcaac
    15601 aagaagcaga tttttatggt tctatggatg gagcaaataa gtttgtaaag ggagatgcca
    15661 tagcaggtct tatagtaacg gcaataaaca taataggtgg aattgtaata ggagctgtaa
    15721 tgctgaatat gactcttatg ggtgcagcac agacatatgt aagacttact gtaggagatg
    15781 gtcttgtaag tcagatacct gctctattaa tatctacatc agcaggtata atcgtaacaa
    15841 gagcttctac tgatgaaaac tttggtggat tagtaggtaa acagttaaca gcaataccaa
    15901 aagcagtaat gatgactggc tgtgttctaa tcgtacttgg tatgatgcct ggattaccta
    15961 aaccagcatt tttttcacta ggtataggtg ctatagcagc aggttacttt ttaggaagag
    16021 aaaagaaaga tactttagaa gacttggagt ttgaaaaacc tgatatggta aatccagata
    16081 aaaatgaagt agaagatgta acaaacttaa taaatgtaga atcaatagaa gtagaaattg
    16141 gatatggttt aatatcttta gctgatgaat cagcaggagg agatttactt cagagaatag
    16201 catcaataag aagacaatgt gcaatagaca tgggtatagt cgtacaacct ataagaataa
    16261 gagataattt acagttaaat ccaaaccaat acaatataaa aataaaaggg aatgtagttg
    16321 gtgggtatga gataatgcct aatatggttt tatgtatgga tcctatgaat caaggattta
    16381 gtatatttgg aataaagaca attgagccta cttttggaat agaggcactt tggatagaaa
    16441 gtgacaaggt agaagatgca gagttaaagg gttatacagt tgtagattca tccacaatac
    16501 ttataactca cttactagat ataataaaat caaatgcaca cgaattactg ggaagacaag
    16561 aagttaagac tattatagat gcagcaagag aaaattatag tgctgtagta gatgaattga
    16621 taccagattt gatgacactt ggtgaaattc aaaaagtact taaaaatctg ttaagagaaa
    16681 aagtaaatat aaaggataga gttacaatac ttgaaacgct tgcagaccag tctagaaata
    16741 caaaagatat agagcttctt actgaatatg taagaatagc cttggctaga agtatttgta
    16801 ataatttagt tgatgatgat aagacaattg tagtggctac attgtctcca gaaactgaag
    16861 agttgatatc taataattta cagaggtctg taaatggaac ttatccagca gttgacccag
    16921 aaaatacaaa taaaatattt gaaagtatac aagaagtaat gagcaatgta tatttcaatc
    16981 ataatatacc agtaatagta gtatcaccaa agataagagc tccatttaga aaattagttg
    17041 aaattgtata tcctaatttg actgtattat cattaaatga aatacctaac gatattaaaa
    17101 tcaaagcaga aggtgtggtg agcatatatg atgacgaaaa agtatacagc taacacaatt
    17161 caggatgcta tgaatctagc caaaatggaa ttgggtgaca atattacatt aatagataaa
    17221 aaagaagtaa gaaagtctgg aatacaaggt atcttttcaa agaaagatat tgaactaact
    17281 attggatggg aaaagagaga aaacatagaa caaaaagatt taaaacgaga gatagaacaa
    17341 ttaaagttaa ttattaacaa tatggggttt gataataaga atgataatga tatagataaa
    17401 atatgtaaaa atctactaag tttagaattg aatgaagaaa ttgtagaatc tataagaatt
    17461 gatttgcaag aaatgaagtt caatggaatc gatacaagta aaaatttagt agaaatttta
    17521 aagaaaaaga ttaaaataga aaatcaagta ataaatggta aaattgctct agtcggacca
    17581 ccaggagtag gtaaaacgac tacaatagca aagttagccg caaaattagt ttttgaagaa
    17641 aataaaaaag taggagtaat aactatagat acatacagga ttggtgctgt agaacagttg
    17701 aagatatata ctgatataat gaatattccc tttaaagggg taataagtcc tgatgaaatg
    17761 gaattggcac ttgacgagat gaaagattgt gatgttgtat taatagatac aacaggtaga
    17821 ggctataaaa actctatgca aatactagaa atcaaaaatc ttatagataa agctgaaact
    17881 gataatatac atttagtttt gaattgtaca acaagagaaa gtgatacaaa agcaattata
    17941 gattcatata gaaatgtgaa ttttaaaagc ttaataatta caaagctaga tgaaacaata
    18001 acatatggat caatatttaa cataatgaat tatgcacaaa aaccaatatc atatattaca
    18061 acaggacaaa atgttcctga tgatattata aaacctaatg aagataagat tataaggtta
    18121 ctattaggag ttgaaagtat atgatagacc aagctcaaat tttgagaaaa atggcaatgg
    18181 aaaaaagagg acttgatgag tttatagtag agaatgagaa tgtacctaag ataattacaa
    18241 tagcttctgg taaaggcggt gttggaaaga gcaatctcgc tacaaatttg tctatatgcc
    18301 tgaccaaact taataaaaaa gttcttatat tagatgcaga cataggaatg tctaatatag
    18361 atataataat gggggtaaat gtaaaaggga ctataattga tgtaattaat ggcgaaaaaa
    18421 atatagaaga tataatttca cagactaagt atggtgtaaa tataatatct ggaggttctg
    18481 cccttaatca tatagaagac tttacagaag ctcaaagaaa taagtttata catagcatag
    18541 aacagattca cgatgtggat tttataataa ttgatacagg agctggtatg agcaaaagct
    18601 tattgtcatt tatatactgt agtactgaat ttttcttaat aacaactcca gaaccgacat
    18661 cattgactga cgcatatagt ttgttaaaag ctataagtaa ttttggcata aagagaagtg
    18721 caaatataat aatcaatagg gtaattgatt tagaagaagc aaaatctaca tacaaaagaa
    18781 taaaaatggt tgtggacaaa tttctaaacc ttaatctaga attgtatgga tatataatag
    18841 atgacaaaaa agtaagttta tgtgtaaaaa aacagatacc attcatttta gaatatccta
    18901 caagtattgc atcaaaatgt attatagcca tagcaaagag aatggtaagt cagtcaagag
    18961 aagatattgt tgataataaa agttttctaa gaaagatgtt tagtatattt aaaagctaag
    19021 gaggcgtagt taatgaatag agaagaatta ataaaagaga atatgcctct tgtaaagagt
    19081 atagcaagaa aattttttat accagggaaa ggttttgaat atcaagactt agtaaatagt
    19141 ggagtcattg gattgattga tgcaataaat aaatttgatg ctgaaaaagg ggcaaagttt
    19201 tctagttact cttatataaa aataaaatct gctatattag atgaaattag aaatcaaagt
    19261 ccaatttcta aacataatct aactaaagta aataagtata atagagtggt agaaaagttg
    19321 caatctaaat tattaagaga gccaacttca tatgaaattg caaaagaatt aaaggtttca
    19381 gaaaaagaac ttcatgatat cgaaagtaat atagatatgt taaatattgt atcattaaac
    19441 tatgtaatct ttgaagatac aaatgaaact gtacaagatg taataagtga tagagaagag
    19501 gaagctccag aaaatataat agaagaagaa gaaaagttag agattctatc caaagcaatt
    19561 agtaatttaa atgaaagaga aaaattaata ctttcactgt actattatga agatttaaat
    19621 ctaaaggaga tagggaaagt gctaggtgtt tcagaatcaa gagtttcaca actccacaga
    19681 aaatcaataa gaaacttaag aaacaagata aaagaactta aatattctat atagatggtg
    19741 attgataaga tgatacaaat tatattaata gtagtgtcta ttttaataat agtaactata
    19801 gttataaatt tacataagga atcaaaaaat aaagataaca gatactttga taaaatattt
    19861 gagcaagaat atgaagcaaa tgatagatta ataattgcag aaaaaagaag attcttttta
    19921 gacaaagtac ttgcagaaaa aagaattaat agtcatataa aagtttatga aaattataac
    19981 ctaataaagg ctaatgaaga aagaaaggaa aacatattta tagaatcaaa aaaggaagta
    20041 agacaagaaa atgagttatc tcttaaagtg aaacatctta taagttcagg ttatgatgat
    20101 gtggaaatat gtaagatgct agatattgga aagggggaac tgttattaat aaggagttgt
    20161 tacaaaatat aaggatatta ttatgtgata aaaaagtatt cttaggaata ggtattggta
    20221 tattaatatc aactttatgt ataatgcttt ttagtaataa tgatatgagt aaggcagaga
    20281 tagaaaaaaa ggccagagcg ttaggcatga aatatacaag tgagatgaaa gttttagaat
    20341 agatgatatt gtttagacat ttacaaaaaa ggaggtcata atgtgataag aggattatat
    20401 acagcagttt ctgctatgat aactaatcaa caaaagcaaa atgttgttgt caataaccta
    20461 gctaatatgg atacaaatgg atataaaagt aaacaacttt tgactaaaag ttttgatgaa
    20521 ttaaagttgg agggttacaa taactacgca aatggaacta aacaaaagca gattataggc
    20581 gatataagtc caggtatttc tatggatgaa actatcacaa attttaatca aggacctata
    20641 aaaactactg ataataaaat ggatgtagct attcaaggta agggattttt tctagttagt
    20701 gatgcagctg gaaatcaatt ttacactaga aatgggaact tcagaacaga caatcaaggt
    20761 gaccttataa caagtgaagg gtattatgta cttgggacga atactgctac tggtgctgta
    20821 ggtcatataa atgtaggaaa tcaaaaattt gaagtggcaa aagataatac aatatcacta
    20881 gacggaaatg ctatgtataa atttaatatt gtagatttta ataactacaa taacttaaaa
    20941 aaagaaggag ataacttata ttctggagga ggagctatga aagtaaataa tgcacttaca
    21001 atacaaagtg cgatagagtc ctctaatgta gatatggtat ctgaaattaa taatatgatg
    21061 acaatatcaa gagaatatga ggcaaatcaa aagataattc aggctatgga ttctaaatta
    21121 gcaaaaatag caagtgagat tggttcagta agataggtaa taggaggtga atttttatgt
    21181 acacaatgtt ttatactagt aaaacagctt tatcagcaaa tcaaagtaaa ctagatataa
    21241 tatctaacaa tatagcaaat tctgattcaa caggatataa aaaaataaat atggaatatt
    21301 ctgatttagt ggatgaagta ctaaatagac catcatatcc tacaaatggc aatgatatat
    21361 cgactggaac aggagctaag gcaacagctc ccatgagaaa ttatgaacaa ggtgcattgg
    21421 ctcctacaga tagtaagagt aatttggcaa tagatggaga aggattcttt agagtgataa
    21481 gaaaagatgg tacatatgca tatacaagaa atggtggatt taatgtagat gctttaggta
    21541 agattgtaga tgataatgga aatatattag atgtccaatt tgatgcagga tataactata
    21601 ataatacaaa tatagatagt acaaacctga cagtttcaag aaatggagag ctattcgtag
    21661 ataataaaaa aataggaaaa atcaacttat atcaacctat aggaactcaa aattttatat
    21721 ctgaaggaga tagtttattc gtcgcaactg atgcagcaca gattaaacaa gttgagaaag
    21781 tcgatatagt tcaaggctat agagagaggt caaatgtttc tttacaagaa gaatttgttg
    21841 acttaatagc cactcaaaga gcatttcaaa tgaactcaaa gggaataaag acagcagatg
    21901 aaatgtggca aatagcgaat aatttaagag ctaaataatt atgtaaggtg aggaatattc
    21961 atgaatgata tgaaagagta cgattttggc aaacctcaga gttattcaag agaaaattta
    22021 acttgtttaa attttttatt agctgaattt tgtaaaaaat ataaaaacta tataatttat
    22081 gaacttaagt gtaattctag tatggttgtt gatagtatag accaagtaaa ttatcagact
    22141 tttttagata gagtaacttc ttcatgcgta gtagtacaaa atgcaatgga acctgttatg
    22201 aaaaactttt cttttagaat agatagaagt gtagctgata tgtggattga tataacttct
    22261 ggaggaactg gagttgtaaa ggataatgat agagaactta cagaacttga taaaaaagtg
    22321 cttttacacc ttatggatga tttagtaaga aatatgcact tatttgaggg ttttgaaaat
    22381 atacaagtat tggatacaca tacacatatt aatttgccac aattatgttc tccaactgca
    22441 ccagtatgcg ttgtagattt aaaagtgcta aatgataatg agtatattgg aagtgtttct
    22501 ctttgctttc catacaatgg tttagaggct ctgttagaaa gtatatctgt tatagaattt
    22561 tttgataatg atgtaggaga tgattcagag gaatttaccc aaaaaatcta taatagtgta
    22621 tctaatatag aattatcagt tattgcagag ataggaaaag tatcaattaa tgttgaggat
    22681 ttactcaaac tagaagttgg agatgtaata gtaacaaata aaaaaataaa tgattatata
    22741 gatatatttg tagaaaattc aaaatcatac acagcaacac caggatttat atcaagtaaa
    22801 aaaggtgtaa aaataaatga tgctgttgga aaagaggtgt agttatggac aatagtaatc
    22861 ttatttcaga tgaagaagca aagatgttat taaatgataa agttgaaagt gaagttgatg
    22921 gagatgatga gttagcctta gatgtctctg aagttaatcg aaataatata caaaggatac
    22981 ttgaccttaa gttagaatta tctgtagtta taggaagaac taagatgact ctaagagata
    23041 ttttaaattt acataaaggt tctcttattg aactggatac tttggcagac caagatgtgg
    23101 aaatactaat agataataag gttttggctt atggaaaagt agtggtggta gatttaaatt
    23161 ttggtgtaaa gataacaagt atagtaagtg aagaagacat ggtaaaatct cttgtttaga
    23221 gataacatca attaatactt aaggcatgag gtggtactta ttttaaactt aaatgatata
    23281 aaaaaagata tactaaaact caataaaaaa gactcatgtt ctctatataa tgaatctatt
    23341 aataatataa ataataattg tatatcaact ggattaaaat ttttaaaaca agcaagagat
    23401 ttaaacccag atgatgttga tatattaaat ctcacaggtc ttgtaaactt actaaaatgt
    23461 aattttgatg atgctgtaga aagtttctat aagagttcac tttgtgaaaa aactgctctg
    23521 tgtgaaaagt atataaacat gcttacatct gaggagtttt taattttctt tgaaaagtac
    23581 aatcaactta taaggttaat aaataaagga atgtataaag aagctataca agggtttaaa
    23641 cttataactg accaatactg tgatttaata gaaccttatg agttgcttgc cttactgtat
    23701 gacaaggaag aagaatatat aaaatttgat gaatgtttag aagtattgaa gattattgat
    23761 aaggaaaatt atttattaaa tcaagaaaat aacacattat atatgtataa tagtgctaat
    23821 atacaaacta aaagtaatat aaaagtagat gattataaga atgagttctt acataaaagt
    23881 agtagtaacc ataaaattaa tgattataat gatgtaacta aagaaaagag ttcaagcaaa
    23941 aaccagaaaa gttcagattc taataagaaa aaaagtatta aaaaaaataa gtacctatat
    24001 atagccataa tattaggaat attattagta ggacaaagta tatatagttc ttataagatg
    24061 aataatttaa ctgataaaat atctaaaaat aatgaaacta aaaatgaaga gtcaatagat
    24121 tctaacttga ctaagaaaga aaataatata gaagaaaatg aagatatgag taaggcttct
    24181 aatataaata agagtaataa aaacattaat aaagaggatg atgtaaaatc taaaaaaaat
    24241 actgtagaaa atgaagatga taaagattct gacttattta cagaggatga attgatgtct
    24301 aaggcgaata ctttaaaatc agaaaagaaa actaaatctt ctatacaact atataagaaa
    24361 gttgcagata taggtgaaaa taaagggaat acatctgaag caacttatca agttgctatt
    24421 ctcagtgaaa agttaaaaga ctataaaact gctgaagaat attataaaat gtatgtagaa
    24481 aattactcag aaaaagatgc ttattttgat gaatcttatt ataatttagg tatgatgtac
    24541 tataacaatg gtgatttaaa aaattctaaa ttgacattaa agaagttggt taataaggta
    24601 ccaaatagta tgtataataa ttcaaaagta aaagaaattt taaaagaaga atagttaaat
    24661 tagataagaa aaataaatta ttttatttta aaataa
//
LOCUS       DAMKNB010000051        24536 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.053, whole genome shotgun sequence.
ACCESSION   DAMKNB010000051 DAMKNB010000000
VERSION     DAMKNB010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 24536)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24536)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24536
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.053"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            complement(450..626)
                     /locus_tag="PC494_002347"
     CDS             complement(450..626)
                     /locus_tag="PC494_002347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3912843.1"
                     /translation="MFIGEIDKCTHILTAYISSSYDYCNFLDTQLDDFISEYGETVVE
                     TCLHQVLLLVSRYN"
     gene            1201..2223
                     /locus_tag="PC494_002348"
     CDS             1201..2223
                     /locus_tag="PC494_002348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3912844.1"
                     /translation="MVNWEIKKLAKSKSMFISLGILVLILMISIFIAPVLETESYYID
                     KEKGRIEDTRSGIDVGNEKFQNKINVLKQFSNQTDTGEFSKKIELMSKKKLDNLSVNE
                     YKDISFWKVFNYRVTNSLINVGMLIIISIIISNIYVDEVVTSVKDIILSSKEKKKALK
                     SKIFVALLVPLVIYSVYLMGIFIITCMQQGVPVNGDLESFRIVDNVVALKTNLSITKY
                     VILNIGIELLMFEGWAMIAIFGSFISKSSISSISFFIFIISITKIMSVIHILPKKLLS
                     VVSNVNYYDLIFGFNKIIGNYLGDIMIFKVNIDIVNIAIGLLMAILIGAMSLCFLVIK
                     SDYISR"
     gene            2237..3124
                     /locus_tag="PC494_002349"
     CDS             2237..3124
                     /locus_tag="PC494_002349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011948651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF3912845.1"
                     /translation="MNKLEIENLSKIYGKKVANDKITVTLENGVYGLLGPNGAGKSTL
                     MKQITTLIKPDEGQILYNGEDIFKMDADYRNILGYLPQEFGVYKNFTAKEFLQYIGAL
                     KGLRGKYLNSKIGELLDLVGLYDVRNKSIGKFSGGMKRRVGIAQVLLNDPKIIVLDEP
                     TAGLDPQERARFRNLIAKMSRDKIIILSTHIISDIESVAKETIMIKDGKLLMKGTHKD
                     ILSHMENKVYNVQVKNECEVDDIQSKYKVVSIQSDIDSIVLRIVSEDIPSEDNIQPVQ
                     AKFEDVYMFYFDLEDAREV"
     gene            3130..3903
                     /locus_tag="PC494_002350"
     CDS             3130..3903
                     /locus_tag="PC494_002350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF3912846.1"
                     /translation="MMYLVKAEMIKILKSKSVWIIWLFLIVFGFFLIRKFDVLDTYAD
                     IFYKIEGSIPLIGLIMFIITSGNYIKEYDSNMTGLINTTKKGKKSVVLSKLVANGLIL
                     SIINISFILLVGIRGFSFFDFKNLNESIHNLWYFGNSNLNLTVIQMYIIVILTTIFAS
                     FIFAQIGLTLSSIFKSAVIPFILGGLIMAIPYFSVGFIPDKAIKFMSVTPNWIMMSQQ
                     MVKYNVPSILIVFSIVISIILMIVLTKITYENFTSSKRF"
     gene            4015..4740
                     /locus_tag="PC494_002351"
     CDS             4015..4740
                     /locus_tag="PC494_002351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012450879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF3912847.1"
                     /translation="MENRVLIIDDEVEILKLLETVLKKEGLNNIYTAKTKKEGLELFK
                     SINPDLIVLDIMLPDGEGYDICKEIRKTSNSPIIFLSAKTEELDKLLGLAIGGDDYVT
                     KPFSPKEVAFRVKAHLRRLSYFSDAQNESKNLNNNEEKIISFGPYILNESRAELIKDG
                     KSIGLSAKELKILSLFAHNQNQIISKEKLWDKVWGEDYVGFDNTIMVHIRKIREKLED
                     NPSKPEYILTIKGLGYKLAVKED"
     gene            4744..6147
                     /locus_tag="PC494_002352"
     CDS             4744..6147
                     /locus_tag="PC494_002352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF3912848.1"
                     /translation="MKWKITRNFIFTIVFVAISVVIINIISILYVISTNSFFKVVDSG
                     NNPEEFARSFEKDLYEKDGEFKLSKIGAEKLEKSNSWIQVLNDLGEEVYGVNVPKDTP
                     KKYTPFQMVNNYKYIETKYVNFVLEKYLNKKHLNIIVGIPSRDISRIILTYSQNNIKK
                     TLNKVIIITLVIDSVVALGVGYLFSRKLTKPISSVLWSIETMANGNYSLYLKDRGIYE
                     EVFKNINMLADTLRVNEVERKENEELREEWLANITHDIKTPLASIQGYAEIINDKDYE
                     FEEDEIQEYTEIIYNKSKYIKDLVDDLNLSTRLKNNTIVLDKKKINLVSLVRNIIIDI
                     LNDNRYKNRNIEFESNEDLIEVYVDSILFRRAITNLIFNSIVHNSEGTLISVEIVKKD
                     NIEIIIKDNGIGISKSDLKHIFKKYYRGTNTGEMHKGSGLGMAISKEIIEIHKGKIYV
                     SSEIGIGTKIIIEIKQN"
     gene            6158..6982
                     /locus_tag="PC494_002353"
     CDS             6158..6982
                     /locus_tag="PC494_002353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraX"
                     /protein_id="HDF3912849.1"
                     /translation="MDFFKKGISGFTIKILALIFMTFDHIAAFMPQTMQIPIWFHWVG
                     RISAPLFIFMAVEGFYHTSNRKKYISRLYIWSVIMAIGNQIINNVFSHPEGAIIINNI
                     FSTLFLIAIYLQAIEFIKKFRKEKEIKYFIIGLLMIIIPIILGIFTVALLFKVTNRVI
                     ALFMILVPVPFLVEGGPIWIILGIIFYLCRGKKFSLSICYVLMCIFIFTTMSNGDYSL
                     KNSILQNYQWMMIASLPLMLLYNGEKGKSMKYLFYLYYPIHVYILYILGIYLINGF"
     gene            complement(7307..7927)
                     /locus_tag="PC494_002354"
     CDS             complement(7307..7927)
                     /locus_tag="PC494_002354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HDF3912850.1"
                     /translation="MKVLLINGSPNQYGCTYTALNEITKVLSKHDIKTEILYLGKETI
                     PGCISCASCFETGKCIRNDKVNELIEDLDNIDGIIIGSPVYFSSATGQLTSFLDRLFF
                     IAGSRMATKLGASVVSCRRGGASATFDQLNKYFSISNMPIVSSQYWNQVHGFTPEDVM
                     KDEEGLQTMRTLGENMAWLLKCISAGKKAGIKEPQYEETIMTNFIK"
     gene            8193..8525
                     /locus_tag="PC494_002355"
     CDS             8193..8525
                     /locus_tag="PC494_002355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF3912851.1"
                     /translation="MSIDCISNTDLSETGFSYTLSLISGKYKMIILYCLVEFEVVRYN
                     ALKRYINTISYKTLSLSLKELEADNLIIRTEYPQIPPKVEYSLSERGKSLIPILDAMC
                     EWGERNRP"
     gene            complement(8645..9286)
                     /gene="pcp"
                     /locus_tag="PC494_002356"
     CDS             complement(8645..9286)
                     /gene="pcp"
                     /locus_tag="PC494_002356"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HDF3912852.1"
                     /translation="MKILLTGFDPFGGEPINPAQEAVERVNNNINGAEIIKITIPTVM
                     TKSVEAIDKAIQEHNPDIVISVGQAGGRFDITPERVAINIDDFRIKDNEGNQVIDTII
                     KEDGEPAYFSKLPVKAMVKHMNENKIPASVSNTAGTFVCNHVMYGILYMIDKKYPNIR
                     GGFIHIPYTTSQVIDKKNTPFMSLEEIVKGLELAIEACIIYKEDVKEIGGEIS"
     gene            complement(9307..10239)
                     /locus_tag="PC494_002357"
     CDS             complement(9307..10239)
                     /locus_tag="PC494_002357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HDF3912853.1"
                     /translation="MQNFINISLEIFYALMGFLMIVIAYKSFTTINNNKKYGTSLFWI
                     LISLPFIFGRLIPANIIGIILILSSLLTLSKQVVFAKYEEPDENFGKEQADKLKNKIF
                     IPSLILAFAAVVVAMSLSNFDNSSQFAIGVGSIIALISALIITKAKPATSVQDGSRLL
                     QQMGPASMLPQLLVALGALFTQAGVGEVISTMISGVVPADSRLFGVIAYVLGMVIFTM
                     IMGNAFAAFSVITAGIGIPFVLSQGGNPAIIGALALTAGYCGTLLTPMAANFNIVPAA
                     LLECKNDYIVIKYQAPVALVLIIAHILVMYFLGF"
     gene            complement(10261..10926)
                     /locus_tag="PC494_002358"
     CDS             complement(10261..10926)
                     /locus_tag="PC494_002358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HDF3912854.1"
                     /translation="MIKLIGILIVVIGFILKIDTLFTVLLAGVATGIVAGLDFNQIFT
                     ILGDSFVSNRGVSLFILTLPVIGVLERYGLKQRAVSLIEKLKRLTTGKVLTIYMIARQ
                     IAGALSIRMSGHPQFVRPLVNPMAQAAGLSNSDELKESDEEAIKALSAASENYGNFYG
                     QNLFAGSSGVLLIASTLTQFGYNVTGLNIVKASTIMAVIALVVATIQFTLYDKKLNKS
                     HKK"
     gene            complement(11498..11974)
                     /locus_tag="PC494_002359"
     CDS             complement(11498..11974)
                     /locus_tag="PC494_002359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin domain-containing protein"
                     /protein_id="HDF3912855.1"
                     /translation="MNTIIIYSSKYGCTKDCANILKNKLSDNVTIVDINNNNNKIELS
                     KFDKIIIGSSIYVGSVSKKIQVLCNDNVELLNKKQVGIFLCCGFSEQADKYLKSNFPS
                     SLLESANAIGIFGSEARLEKMKFLDKLIMKAVSKGNYDSFRISQDNIDNFLINLNS"
     gene            complement(11977..12381)
                     /locus_tag="PC494_002360"
     CDS             complement(11977..12381)
                     /locus_tag="PC494_002360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FMN-binding protein"
                     /protein_id="HDF3912856.1"
                     /translation="MKIRNKATNKKKKYVKISIALFFVFICIIIVIVSNLKPENLVVK
                     DIDINNVKNGIYTGSADNNLVKATVSVEVNNGKIQNINILKHDHLLGKPAEKITTSII
                     KQQSLDVDAITSATYSSNTIRKAVENALRKGE"
     gene            complement(12356..12985)
                     /locus_tag="PC494_002361"
     CDS             complement(12356..12985)
                     /locus_tag="PC494_002361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDF3912857.1"
                     /translation="MSIKERRKNEKEEMKKKIMDASIEIINQHGYENLSIRKIATKIE
                     YSPTTIYLYYKDKAEIISDMTNKLYNTVESNAIDIMNNCSSLPIDKQIIEIMTSFIKT
                     LSSEPEMAKSIMHSRMNIIFASENTNNTPSNNGIKMLDKFLSIGIEQGIFKKNIDKSS
                     WMLISALLGFVLCVVENKLYSLHNFSQLIENFLDILVGGLYNENSQQGY"
     regulatory      13351..13394
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00522"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF00522"
     gene            13495..14463
                     /locus_tag="PC494_002362"
     CDS             13495..14463
                     /locus_tag="PC494_002362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside hydrolase"
                     /protein_id="HDF3912858.1"
                     /translation="MEKRKVIIDCDPGIDDSLAILLALNSPELEVIGITTCCGNVPAN
                     IGAENALKTLQMCSSLNIPVYIGEEAPLKRKLVTAQDTHGEDGIGENFYQKVVGAKAK
                     NGAVDFIINTLYNHEKVSIIALAPLTNIAKALIKDKKAFENLDEFVSMGGAFRIHGNC
                     SPVAEFNYWVDPHGADYVYKNLSKKIHMVGLDVTRKIVLTPNIIEFINRLDKKMAKYI
                     TEITRFYIDFHWEQEGIIGCVINDPLAVAYFIDRSICKGFESYVEVVEDGIAMGQSIV
                     DSFNFYKKNPNAIVLNEVDEKKFMYMFLKRLFKGYEDIIDSVEGVI"
     gene            14465..15028
                     /locus_tag="PC494_002363"
     CDS             14465..15028
                     /locus_tag="PC494_002363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HDF3912859.1"
                     /translation="MKRKICVKTITLIAFGISINIIGAFIAMGLRLPVYLDSIGTIMI
                     ASLLGPKYAVVTGVFGSLISGITFDVYSLYFAPVQISTGLLAGIAFKKNFLRGLKTPL
                     GVLLFAIPTSIISSIISAFLFGGMTSSGSSYIVQILKVLGLGDVFSVFVTQVFTDYGD
                     KLLAVVLVNLGLNAVPKTLKVSLTGGK"
     gene            15036..15725
                     /locus_tag="PC494_002364"
     CDS             15036..15725
                     /locus_tag="PC494_002364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HDF3912860.1"
                     /translation="MDRYSEITNKNQREIVLLKGFPCIWGKCSFCDYIDDNSNLEEEM
                     NKLNLKVLKNVTGKYGVLEVINSGSCFELPKDTLEKIKCIIKEKNIKKLFLESHWSYK
                     NRLKEMREYFEIPVVFKIGVETFDNDFRNNILNKNANFKTPQDVKEYFDSPCIMVGIK
                     GQTKEMIDKDIEIILNTFEKATVNVFINNSSSIKRDEELVKWFVSKYKFLDENPNIEV
                     LYNNTDFGVGD"
     gene            15852..16580
                     /locus_tag="PC494_002365"
     CDS             15852..16580
                     /locus_tag="PC494_002365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HDF3912861.1"
                     /translation="MMFDRGKWNKLDYNELLEYMMSIQDIKYRDFNKKLIPGTENIIG
                     IRVPNLRKLSKEISQGNWKEFLEVAQDTYYEEVRLQGMVIGNINSNFEETLYYVKRFI
                     PKIDNWSVCDGFCSDLKSMKKYKENMYDILKKYVYSKNPWEIRFALVMFLIYYVDDKH
                     IKEIFEYCNNIQSEEYYVKMGMAWLLSICFIKCEEETFLYIKNNNLDDFTYNKMLQKI
                     IESNRVDLEKKNIIRSMKRKTRRC"
     gene            16594..17268
                     /locus_tag="PC494_002366"
     CDS             16594..17268
                     /locus_tag="PC494_002366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HDF3912862.1"
                     /translation="MNNNEDRIDKFLELQSKGFKFAEIAQNLKISQSTLRTFLNKKGY
                     KSEKGKYILKDELNYNKSLDNRNLEEEKAKEYEKSKKNTISNRKKVSTKKKISNEKAL
                     SKSVEQIEFNDTGLKNAKPKQNIKPKKDRKINITQEDLDKLCEVYDWYLEVKDYNIKP
                     KKVSNKKDVHIDDEHIDELKTTRIRIDKEIWNDFERLCSNSNFEKHQILTQALKEFMK
                     KYKNLL"
     gene            17294..18130
                     /locus_tag="PC494_002367"
     CDS             17294..18130
                     /locus_tag="PC494_002367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3912863.1"
                     /translation="MNKIVKKSISLMIILTIFIFMLTACEKDEQPDSVDIQTEDKNEI
                     KIDEGNAKVLNIGKSEIINIDEGDKVDTSTKVENNSTFNISNVELIYNEYDENKKIIS
                     SDSKALLDMTLMPGKVAYIECGHKTFVKGVEVYAYEYEAEGKIVYVNLKENTINIRNN
                     NIKLENSSQYEVLSTSELKKVNESNEGITYQVKVKNSSSKDLGNIILKTAEVNENGEY
                     LTVNRVPSYKILKPSEETDIDILCSTKAKSVEIVGYTYDDIKEKANVDIDLKSHKVKI
                     DK"
     gene            18146..18817
                     /locus_tag="PC494_002368"
     CDS             18146..18817
                     /locus_tag="PC494_002368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF3912864.1"
                     /translation="MKVLIVEDNKILLESVVEELSKHFETEKCEDGEEALYLINQNIY
                     DLVILDLMLPNINGFDILKKMRINNIDTPVLILTAKETLDDKVEAFTIGANDYLTKPF
                     YMEELVARVYAILRTNGKIKERNGLEFKSLYLDTLEKRVYIEKEEIKLQNKQFNLLEY
                     FVLNKGSILLKEQIYDRIWGIDSDATIEIVEVYVSNLRKKLSKYGYDKYIKTKRKVGY
                     IFDDK"
     gene            18807..20039
                     /locus_tag="PC494_002369"
     CDS             18807..20039
                     /locus_tag="PC494_002369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF3912865.1"
                     /translation="MINKNVFTSTKNHLIKMYIIVVGSFLIIFSIFIYSYFRGLTYSG
                     IDSEINDELEYIVSQFKRTSFLNPIRLKDPKDMVYVYEDGRISYYTQNEYFDELLPDR
                     RLDKKNSFFKYTENGYTFRELNVDVGRYQIQIIRNIDSEMNSLRQLTSVLIIGILISV
                     IITYFVAVYLTRKALIPIETAWKNQAKFIQDASHELRTPITIVSSKLESMLKSPESTV
                     NDEVETIATAMKETRRLKKMITDLLSLTKEDSIVKVNLEEIDLEKLLEEISEDYIDIA
                     EFQEKRFVFNSKLKNKVIITDKNKLRQLILIFIDNAFKYTKLGDEIALELKEDIEDEV
                     TLLISDTGIGIKKEEIPLIFDRFFRSENVRNKDLEGSGIGLSIARMISLNLSIDINVT
                     SDVDIGTTFELSIPKKLK"
     gene            20189..20506
                     /gene="trxA"
                     /locus_tag="PC494_002370"
     CDS             20189..20506
                     /gene="trxA"
                     /locus_tag="PC494_002370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HDF3912866.1"
                     /translation="MAKVINTSEFRSSVEGSKGVVVVDFFATWCGPCNMLGPVFAELG
                     EEMKDKARFVKVDIDESLEIAQQFNVSTVPTMIIFKDGKPVETLIGFMPKNKIEMQVK
                     SYL"
     gene            20523..21401
                     /locus_tag="PC494_002371"
     CDS             20523..21401
                     /locus_tag="PC494_002371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HDF3912867.1"
                     /translation="MRYDIAIIGSGPAGLSAAINAKIRNKTIIMFGNDNLSNKLVKAP
                     SIDNYLGFYDISGDELKDKFKSHIDSMDISIENKRINNIYAMGEYFTIMSGNDMYEAT
                     TVILATGVEYTRPIKGEEEFLGRGVGYCATCDAPLYRNKKVAVIGYNEESKEEANFLS
                     ELTSKTYFIPMYKKDNLMRSSDNLDDSIEVIHDRPVQIDGDKLVNKVSFKENHIEVDG
                     VFVIKDSTAPSALVPGIEIDGIHIKVDNNMKTSIDGCFAAGDCVGKPYSYIKAAGQGQ
                     IAALNAVYYLDKLKRA"
     gene            21671..22039
                     /locus_tag="PC494_002372"
     CDS             21671..22039
                     /locus_tag="PC494_002372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HDF3912868.1"
                     /translation="MENLVKIFKALSDETRLNILILVSKRNICQKGISKYLGISDSAV
                     SQHIKILKDVGIITGYKEGYYVLYHINKESFNICVDFINSMLSNSSESFIDVFDVNTI
                     HLGCSKECKSIKKCCKRREK"
     gene            22042..22413
                     /locus_tag="PC494_002373"
     CDS             22042..22413
                     /locus_tag="PC494_002373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NifB/NifX family molybdenum-iron cluster-binding
                     protein"
                     /protein_id="HDF3912869.1"
                     /translation="MKVCIPVEENKGLDSKPYGHFGSAPIFVVCDLESGEVKSLDNGD
                     LDHEHGKCQPLKALSGTAVDAVVVGGIGQGAIIKLNGMGIKVYRAEGDTISANLDLLK
                     NGKLVEFPSDHTCSHDGCGHH"
     gene            complement(22558..23013)
                     /locus_tag="PC494_002374"
     CDS             complement(22558..23013)
                     /locus_tag="PC494_002374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3912870.1"
                     /translation="MNINTVQGDSIEVLLRQLGATRISKVSSTLYFIKFDLGDGWEIS
                     YTYNINAKDQYFLQRIEPYPIGRGLFNDEYEIVSFISKDLKKFLNAKNSSNFKTFVEV
                     TRKVNSIIDNVEELFLNYNVDGDDLKTLNKELNDILNDIDYIEKHTKKI"
     gene            complement(23052..24317)
                     /locus_tag="PC494_002375"
     CDS             complement(23052..24317)
                     /locus_tag="PC494_002375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArsB/NhaD family transporter"
                     /protein_id="HDF3912871.1"
                     /translation="MEFQQIIAICIFLIVMAAIITEKVNRSIAAVGGALLMIIFNILT
                     LDEGLSHIDFNTIGVLVGMMLFVAVVKNSGLFEYIAIWTAKKAKGDPWKIMICFAIIT
                     AILSAVLDNVTTVLLIGPMTIVITQILGLNPVPFLITQILASNIGGTATLIGDPPNIM
                     IGSAANLSFMDFVINLGPAVIVILAITIICFRFIYGKELVVNERAKNAILKLDEKKSV
                     KDKPLLIKSLILIAFILFGFMFHSTIHIDSSVVALTGASIMLLIGKQDVDEIMAGIEW
                     STILFFMGLFVVVGGLVEVGIINKLAQALIGLTEGHLVFTMLLILWLSAIVSSFLDNI
                     PFVATLIPLILTMQAEGIDVMPLWWATSLGACLGGNGTLIGASANVVLAGIGNKHGHP
                     ISFKEYFKIGFPLMIISIIISTVYLIIKF"
BASE COUNT         9466 a         2725 c         3790 g         8555 t
ORIGIN      
        1 aatgcttgtt tttcttgtat tatttatata aatattgaaa tttgtctagt tatacgtttt
       61 tattgaccag ttatgcagtt gatattgaat attctaaata ttggtgttat tttataggtg
      121 gtttaaacat attaggggga ttttatatat gatttgtatg atttatagag aatgtataaa
      181 atagtaaagg tttagagcca tgtttagtgg attgcagaat atgcatatag aatgattctt
      241 gtaaattaag ttagacatag gaaatatata atttgtattg gatgattgat tttatggtgt
      301 atgcttttaa cttctataat gggaaagtaa agatgtactc ccaatacatc tttactttag
      361 cagaagttat agttacttat aaagtacaaa aaattatata tttattagag tagataaatc
      421 taaaaaggtt tttctagaaa aatttagttt taattgtatc tacttactaa taataagact
      481 tgatgtaagc aggtttcaac taccgtttct ccatattctg atataaaatc atctaactgt
      541 gtatctaaaa aattacaata atcatatgaa ctactgatgt aagcagttag tatatgtgta
      601 catttgtcta tttctccaat aaacatatta tccatccccc taaaaaattt agtaaaaata
      661 aaaagtcgca ttctattagt caattaacat aatttataaa attttttagt actagtttct
      721 ataacttaac tccttaaggt taaatattcc cagttttacc aatttagttt tattctacaa
      781 gtatataata ctagaagatg ctccattatt caacatgctt gtttgagaat agaaaatatt
      841 ctaaaattat aattgttttt aaaaataaga ttcaagataa ataaagttat atgcaactat
      901 ttaataatct ttccataata aggacagtag gttctattct taaaaaactc catctttaaa
      961 tttaaagaat aactacaatt tgaacaacaa taaaatttcc aatcaataaa aatatcaaaa
     1021 ataataaaaa taattgaaaa tgtataattt cccagaaaaa taataaatgt aactccaata
     1081 ataaacacac ctataaatta taaaataatt taagctttat ttaaggttag tattatattt
     1141 atataagatt taagttttaa tatatatgtg taattaaaat gatttaggag gagaaatata
     1201 ttggtaaatt gggaaataaa aaaattggct aaatctaaga gtatgtttat atctctaggg
     1261 atattagtgt taatactaat gattagtatc tttattgcgc ctgttttaga aacagaaagt
     1321 tattatatag ataaagaaaa aggacgtata gaagatacga gaagtggtat cgacgtaggt
     1381 aatgagaaat ttcaaaataa gattaatgtt ttaaagcagt tttcaaatca aacagataca
     1441 ggtgaatttt ctaaaaaaat tgaattaatg tcaaagaaaa aacttgataa tctaagtgtg
     1501 aatgaatata aggatattag tttttggaaa gtatttaact atagagttac aaattcactt
     1561 ataaatgtag gaatgttaat cattatatct ataattatat ccaatattta cgtagatgaa
     1621 gtcgttactt cggtaaaaga tatcatacta tcatcaaaag agaagaaaaa agcattaaag
     1681 tctaaaatat ttgttgcttt attagttcca ttagtaattt attctgttta tttaatggga
     1741 atatttatta taacttgtat gcaacaagga gtacctgtta atggagactt agaatctttt
     1801 agaatagtag acaatgtagt tgcattgaaa actaatttaa gtataacaaa gtatgtaata
     1861 ttaaatatag gcatagagct tttgatgttt gaaggatggg ccatgatagc catatttggg
     1921 tcttttataa gtaagtcttc aatatcttca ataagttttt ttatatttat tatatctata
     1981 actaagataa tgtcggtaat ccatatatta cctaaaaaat tactttcagt tgtatcaaat
     2041 gtaaattatt atgatttgat atttggtttt aataaaataa taggaaatta tctaggtgat
     2101 attatgatat ttaaagtgaa tatagacatt gtcaatatag caataggact tttgatggca
     2161 atattgatag gtgctatgtc attatgtttt ttagtaataa aatcagatta tataagtaga
     2221 taaaagggga gttaagatga ataaattaga aatagaaaat ctttcaaaga tatatggtaa
     2281 aaaagtagca aacgacaaga ttacagtaac tctagaaaat ggagtttatg gtcttctagg
     2341 accaaatgga gcaggaaaat ctacattaat gaaacaaata acaacgttga taaaacctga
     2401 tgaaggtcag atactttata atggtgagga tatatttaaa atggatgctg attatagaaa
     2461 tattttagga tatttgccac aagaatttgg agtttataaa aattttacag caaaagaatt
     2521 tttacagtat attggagctt taaaaggttt aaggggaaaa tatttaaata gtaagatagg
     2581 agaattatta gatttagtag gtctttatga tgtgagaaat aagtctatag gaaaattttc
     2641 aggaggtatg aagaggagag ttgggatagc acaagtttta ctaaacgacc ctaagataat
     2701 agtccttgat gagccaacag caggtcttga cccacaagaa agagctagat ttaggaattt
     2761 aatagcaaaa atgtctagag ataagataat aatactttct actcatataa tttccgatat
     2821 agaatcagtt gcaaaggaaa caataatgat taaagatggc aaactcctaa tgaaaggaac
     2881 acacaaagac atattaagtc acatggaaaa taaagtatat aatgttcaag ttaaaaatga
     2941 atgtgaagtt gatgatatac aatctaaata taaggttgta agtattcaaa gtgatattga
     3001 ttcaatagta cttaggattg tttcagagga tattccaagc gaggataata tacaaccagt
     3061 tcaagcaaaa ttcgaagatg tatacatgtt ttattttgat ttagaagatg caagggaggt
     3121 gtagtagaaa tgatgtattt agttaaagct gaaatgataa aaatattaaa atcaaagagt
     3181 gtttggataa tttggctgtt tttaatagtt tttggatttt ttctgattag aaagtttgat
     3241 gttttagata cttatgcaga tatattttac aagatagaag gctcaatacc tctaataggt
     3301 ttgataatgt ttataataac ttctggaaat tacattaaag aatatgattc taatatgaca
     3361 ggtttaataa atacaactaa aaagggaaaa aaatcagtag tattatcaaa actagtagct
     3421 aatggattaa ttttatctat tattaatatt tcttttatat tgttagtagg aattagaggt
     3481 tttagttttt ttgattttaa aaatttaaat gaatcgattc ataacttatg gtactttgga
     3541 aatagtaatt taaatcttac agtaatacaa atgtatataa ttgttatatt gactactatt
     3601 tttgcttctt ttatatttgc acaaataggc ttaacacttt catctatatt taaatcggct
     3661 gtaattccat ttatactagg tggattgata atggcaattc catactttag tgtaggtttt
     3721 ataccagata aagctataaa atttatgtca gtgactccaa attggattat gatgagccaa
     3781 caaatggtta agtataatgt accaagtatt ttgatagttt tttctatagt aatctcaatt
     3841 atattaatga tagtgttaac taaaataaca tatgaaaatt ttacatcaag caaaaggttt
     3901 taactaaaaa taatagtaat tttatttata ttttagttta attaaaaata agataaatga
     3961 attttagata aaatatatgc taatatatat gtaaattatt acaggaggtt gtttatggaa
     4021 aatcgtgttt taataataga tgatgaagta gaaatattga agcttttaga aactgtccta
     4081 aaaaaagagg gtcttaataa tatatatact gcaaaaacta aaaaagaagg attagaatta
     4141 tttaaaagta tcaatcctga tttgattgta ttggatatta tgttaccaga tggcgaaggt
     4201 tatgatattt gtaaagaaat aagaaaaacc tccaattctc caataatatt tttatcagct
     4261 aaaaccgaag aattagataa gttacttgga ctagcgattg gaggagatga ttatgttaca
     4321 aaacctttta gccctaagga agtggctttt agagttaaag cgcatttgag aagattaagt
     4381 tattttagtg atgctcaaaa cgaaagtaaa aatctaaata ataatgaaga aaaaattata
     4441 tcatttggcc catatatatt aaatgaaagt agggcagaac ttataaaaga tggaaaatct
     4501 ataggactgt ctgcaaagga actaaaaatc ctatctttat ttgcacataa tcaaaatcaa
     4561 attataagta aagaaaaact atgggataaa gtgtggggag aagattatgt tggatttgac
     4621 aatactataa tggttcatat aagaaaaatt agggaaaaat tagaggataa tccttcaaaa
     4681 cctgaatata ttctgacaat aaaaggtctt ggatataaat tagcagtaaa ggaagattag
     4741 aatatgaagt ggaagattac tagaaatttt atatttacaa ttgtgtttgt agctatatca
     4801 gtagtaatta taaatatcat atctatattg tatgtgattt caactaatag cttttttaaa
     4861 gttgtagatt ctggaaataa tcctgaagaa tttgcacgtt cttttgaaaa agatttatat
     4921 gaaaaagatg gagaatttaa actatctaag attggagctg aaaaattaga aaaatcaaat
     4981 tcctggatac aggttttaaa tgatttagga gaggaagttt atggagtaaa tgtgccaaag
     5041 gatactccca aaaaatatac accctttcaa atggtgaata attacaagta tatagaaaca
     5101 aagtatgtta attttgtact agaaaaatat ttaaacaaaa agcatttaaa cataatagta
     5161 ggtataccta gtagagatat atcaagaata attttaacct attctcaaaa taacattaaa
     5221 aaaactttaa ataaagttat cattataaca ctagtaattg atagcgtggt agctttaggc
     5281 gtaggatatt tatttagtag aaaacttaca aaaccaattt caagcgtact atggagtatt
     5341 gagactatgg ctaatggaaa ttatagttta tatcttaagg acagaggtat atatgaagaa
     5401 gtttttaaaa atataaatat gttagctgat actttaagag taaatgaagt tgagagaaaa
     5461 gaaaatgaag agttgagaga ggaatggctg gcaaatataa cacatgatat aaagacacct
     5521 ctagcatcta tacaagggta tgcagagata attaatgaca aagattatga gtttgaagaa
     5581 gatgaaatac aagagtatac agaaattata tataataagt ctaagtatat aaaagattta
     5641 gttgatgatt taaatttatc tactcgatta aaaaataata ctatagttct ggacaagaaa
     5701 aaaataaatt tagtcagttt agtcagaaat ataataattg atattttaaa tgataataga
     5761 tataaaaata ggaatattga atttgaaagc aatgaagatt taattgaagt atatgtagat
     5821 tcaatcttat tcagaagggc tataaccaat cttatattta attcaatagt tcataatagc
     5881 gaaggaactt tgataagtgt agaaattgta aaaaaagata atatagaaat tataataaaa
     5941 gataatggaa ttggaataag caaaagtgat ttgaaacata tttttaaaaa atattataga
     6001 ggtactaata caggtgagat gcataaaggt tcaggtcttg gtatggctat ttctaaagaa
     6061 ataatagaga ttcataaagg taaaatttat gtaagtagtg aaattggaat aggaacaaaa
     6121 attattatag agataaaaca aaattaggag atatgatatg gattttttta aaaaaggtat
     6181 aagtgggttt actattaaga ttttagcatt aatatttatg acatttgacc atatagcagc
     6241 atttatgcca caaacaatgc aaataccaat ttggtttcat tgggtaggca gaatatcagc
     6301 accactgttt atattcatgg ctgttgaagg attttatcac actagtaaca gaaaaaaata
     6361 tataagtaga ttgtatattt ggtctgttat tatggctata ggaaatcaaa taattaataa
     6421 tgtattttca catccagaag gagctataat tataaataac attttttcaa cattattttt
     6481 aatagcgatt tatttacaag caatagagtt tataaagaaa tttagaaaag agaaagaaat
     6541 taaatatttt attataggat tattgatgat aatcattcct ataattttag gaatatttac
     6601 agtagcttta ctttttaaag tcactaacag agttattgct ttatttatga ttttggtacc
     6661 agtaccattt ttagtagaag gtggaccaat ttggattata cttgggatta ttttttattt
     6721 gtgtagaggg aaaaagttca gtttgagtat ttgttatgtt ttaatgtgta tatttatatt
     6781 tacaacaatg tcaaatggag attatagttt aaaaaattct attttacaaa attaccaatg
     6841 gatgatgatt gcttctctac ctttaatgtt actttacaat ggagaaaaag ggaagagtat
     6901 gaagtattta ttttatttat actatccaat ccatgtatat atattgtata tcttaggaat
     6961 atacttaata aatggttttt gattgtaagt gatattttta atacaaaatg aacaatatga
     7021 ggattgtttt aggtctatta aaattgttat ttagatgaga tttgtagaat atttaaattt
     7081 atgagcagaa attcagttat tgtaatttca ataacattag aatataatat tataatttat
     7141 ttagaaatat atgatgttat acatggtttg gttattaatg taataataaa acagaggttt
     7201 gatataaaat tcaatacctc tgttttagtg ctttttatcc tacatttatg cttattttat
     7261 ttataaatta gtgttttgtt ttaattaata ttagtgcatt ttttatttat tttataaaat
     7321 tagtcataat tgtttcttca tattgtggtt ctttaattcc agctttttta cctgctgata
     7381 tacacttaag aagccatgcc atattttctc ctagagttcg catagtctgt aatccttctt
     7441 catccttcat aacatcctct ggagtaaagc catgtacctg attccaatac tgtgatgata
     7501 caataggcat attgctgatt gaaaaatatt tatttagttg gtcaaatgtt gcacttgcac
     7561 caccacgtct acatgacaca actgaagcac ctaattttgt agccatgcga cttccagcta
     7621 tgaaaaatag acggtcaaga aaagaagtta attgaccagt tgcactagaa aagtaaacag
     7681 gagaaccaat aataatacca tcaatattat caagatcttc aatcaattca ttaactttat
     7741 catttcgaat acattttcca gtttcaaaac aggatgcgca actaatacat cctgggattg
     7801 tttctttacc taaatacagt atttctgttt taatatcgtg tttactcaat actttagtaa
     7861 tctcatttag tgctgtataa gtacatccat attggtttgg gctaccgttt atcaataaaa
     7921 ctttcattat aaatttcctc ccatgaattt tatttaatag attttctaag agatattatt
     7981 ttttataaaa taggattttc atgaatatta tcaatttata tagaaatgtc taatcttaga
     8041 atcctattta aaataacttt ttttttagta aatacacctc ctattataaa attgactttc
     8101 aattattctt acactataat tttattataa attattctaa aaacaagtac gcacattttt
     8161 gttcaatact aaccaaaagg agagtgtaat atatgagtat agactgtata tcaaatacag
     8221 atttaagtga aacaggattt agttatacac tttcactgat tagtggtaaa tataagatga
     8281 taattcttta ctgtcttgta gaatttgaag ttgtaagata taatgcatta aaacgttata
     8341 taaatactat ctcctataaa actttgagtt tatcattaaa agaattagaa gcagataact
     8401 tgattattcg tactgaatat cctcaaatac ctcctaaggt agaatatagt ctatcagaaa
     8461 ggggaaaatc tctgattcca attttagatg caatgtgtga gtggggagag aggaatagac
     8521 cttaattttg tatctgtaga taccataaaa agactgtgag taaaattgtt tgaataatct
     8581 actcacagtc tatatttaaa ttaatagtta gtatttttaa tttataaaaa tactaaaaaa
     8641 tttattatga aatttcacca ccaatttctt ttacatcttc tttatatata atacaagctt
     8701 ctatagctaa ttctaagcct tttactattt cttctaaaga catgaatggt gtattttttt
     8761 tatctattac ttgtgaagtt gtatatggga tgtgtataaa tccacccctt atattaggat
     8821 atttcttgtc tatcatataa agaattccat acatcacatg attgcaaaca aatgttcctg
     8881 cagtgtttga aacactagct ggaattttat tttcattcat atgttttacc atagctttta
     8941 caggcaattt tgaaaaatat gcaggttcac catcttcttt tataatagta tctataacct
     9001 ggttaccctc attatctttt attctaaaat catctatatt tatagcaact ctctcaggtg
     9061 taatgtcaaa tctacctcca gcttgtccaa ctgatattac tatatctgga ttgtgctctt
     9121 gaatagcttt atctatagct tcaacagatt ttgtcataac tgttggtata gttatcttta
     9181 tgatttctgc accatttata ttattattga ccctttcaac tgcttcttga gctgggttta
     9241 ttggttctcc accaaatggg tcaaatcctg ttaacaaaat tttcattatt ttacctccta
     9301 attatattaa aatcctaaaa agtacattac taatatgtgg gctataatta ataccaaagc
     9361 aactggagct tgatatttta taacaatata atcattttta cattctagca aggctgctgg
     9421 aactatatta aaattagcag ccattggagt aagtagagtt ccacaatatc ctgctgttaa
     9481 tgctaatgct ccaattatag caggatttcc accttgagac aatacaaaag gaataccaat
     9541 tcctgccgtt atgactgaaa atgcggcaaa tgcatttccc attatcatgg taaatataac
     9601 catacctaat acataagcta taacaccaaa taatctgcta tcagcaggga ctacaccaga
     9661 tatcatggtt gaaataactt caccgactcc ggcttgagta aataaagctc ccaatgcaac
     9721 taaaagttgt ggtaacatac tagcaggtcc catttgttga agtaatcttg agccatcttg
     9781 aactgatgta gcaggttttg ccttagttat tataagggct gatattaatg caattattga
     9841 acccacacct attgcaaatt gagaagaatt atcaaaatta gaaaggctca tagctactac
     9901 tactgcagca aatgctaata ttaatgatgg tataaatatt ttatttttaa gtttgtctgc
     9961 ttgttctttt ccaaaatttt catctggttc ttcatacttt gcaaatacaa cttgtttaga
    10021 aagtgttaat aaactagata atattaatat tattcctatt atattggctg gaatcaatct
    10081 accaaatatg aatggcagtg atataagtat ccaaaataat gatgtaccat atttcttatt
    10141 gttatttatg gtagtaaaag acttatatgc tataacaatc attaaaaatc ccattagtgc
    10201 gtaaaagatt tctaatgata tgtttataaa attttgcatt tttattcctc ctaaataaaa
    10261 ctatttttta tgacttttgt ttaatttttt atcatataag gtaaactgga ttgtagccac
    10321 tacaagtgct attactgcca taatagtact agcctttaca atattaagtc cagttacatt
    10381 gtatccaaat tgagtcagag tagatgctat aagtaatact ccactactac ctgcaaataa
    10441 gttttgacca taaaaatttc catagttttc tgatgcagca gataatgcct ttatggcttc
    10501 ttcatccgat tcttttagct catcactatt acttaaacca gcagcttgtg ccataggatt
    10561 aacaagtggt cttacaaatt gaggatgtcc actcattctt attgatagag caccagctat
    10621 ttgtctagct atcatgtata tagtaagtac ttttcctgtt gtaagtcttt ttaatttttc
    10681 tattaaagaa acagctcttt gttttaaacc atatctttct aatacaccga tcactggcaa
    10741 tgttaatatg aataatgata cacctctgtt tgagacaaaa gaatctccta aaattgtaaa
    10801 aatttgatta aaatctaatc ctgcaacaat tcctgttgcc actcctgcta ataatacagt
    10861 aaatagtgtg tcaattttaa gtataaatcc aattacaact atcaatatac cgattagttt
    10921 tatcataaat tgttctcctt ccatttctat atgttttaat ttaaatttat ttaatggata
    10981 aagttaaact ctttttatag tatttgcgtt aataggacta ttattataaa atttaataaa
    11041 aaatagggaa gatgttttaa agtatcaaag taaataatgg ttgtgtatag gaatttgaat
    11101 aacaaagatt atattttaag ctaatatgaa ttgattttgt aagtctatag tttaagtata
    11161 tgtcaatatt tgaaatagta gttttaaatt aaacattata ttataaaaag agaatgtgcc
    11221 aaacatagag acaagtgtat ttttctctgt tgaaatgata aaaatatatt tgatttcata
    11281 caaaaagaga gtgtctaatg aattttttag ttcattagac actctctttt tgttatgatt
    11341 aataaaacat atttgttatg attaataaag catatattaa gtgctagttt cattagattt
    11401 cactaagaaa aataaaattt tgataaagtt taaagactat tttgagcaat attacttata
    11461 aataaaagaa tttatcatag aaataattag ctttatttta gctattaaga tttattaaaa
    11521 aattatctat attatcctgt gatattctaa aactgtcata attacctttt gaaacagcct
    11581 tcataataag tttatctaaa aatttcattt tttctaatcg agcttcacta ccaaaaattc
    11641 caatagcatt tgcactttct aataaggatg atggaaaatt tgattttaaa tatttatctg
    11701 cttgttcaga aaagccacag caaaggaaaa tgccaacttg ttttttgttt aataactcta
    11761 cattatcatt acatagcacc tgtatttttt ttgaaactga accaacatat atagaacttc
    11821 caataataat tttatcaaat tttgataact caattttatt attattatta ttaatatcaa
    11881 caatagtgac attatctgat agtttatttt ttagtatatt tgcacagtct tttgtacaac
    11941 catatttact tgaatatata ataatagtat tcataattat tctccctttc ttaaagcatt
    12001 ttctacagct tttcgtatag tattactgct ataagttgca gaagttatag catccacatc
    12061 taaagactgt tgtttaataa tacttgttgt aattttttca gcaggtttac ctaaaagatg
    12121 gtcgtgtttt aagatattaa tattttggat tttaccatta ttaacttcaa cagacacagt
    12181 agcttttacc aagttattat cagcacttcc agtataaatg ccatttttaa cattattaat
    12241 atctatatct tttactacca agttttctgg ctttaagttg cttacaatta caataataat
    12301 gcatataaat acaaagaata gagcaataga tatttttaca tattttttct ttttattagt
    12361 agccttgttg cgaattttca ttgtaaagtc ctcccactaa aatatctaag aaattttcta
    12421 taagttgaga aaaattatgt aaagaatata gtttattttc aacaacacat aaaacgaatc
    12481 ctaacaatgc acttataagc atccatgagc ttttatctat attttttttg aatattcctt
    12541 gttcaattcc aatggaaagg aatttatcaa gcatttttat accattattg ctaggcgtat
    12601 tgtttgtatt ttcagatgca aatataatat tcattctact atgcatgata gattttgcca
    12661 tctctggttc actagaaaga gtttttataa agctagtcat aatttctatg atttgtttat
    12721 ctattggtag tgatgagcaa ttattcataa tgtcaatggc attactttct actgtgttat
    12781 aaagtttatt ggtcatatcg ctgataatct ctgctttgtc tttgtagtaa agataaattg
    12841 tagttggaga atattctatt tttgtagcaa tttttcttat tgataaattt tcatatccat
    12901 gttggtttat aatttcgatg ctagcatcca taatcttttt cttcatttct tctttttcat
    12961 ttttacgtct ttctttgata ctcatataat cacctctttg cttaacggtg ttaagttaat
    13021 ttacactgtt attgtataat ttaattttaa tactgtcaat aaattattaa ataatataag
    13081 ttaatatatt tttatggata ataaattaat gttattaatt gtaatattta agatattatt
    13141 gtataataat aatcggttta aatgcgccac atcttattaa agttggttca taattctaaa
    13201 taaactttaa taagatacat taaaatataa taaattcttt tatgctataa aatttatttt
    13261 atagctatta aatcagatgt ttaaaaattt tttaacggtc tatagttttt aagagtctta
    13321 tagtaagtag cctaaaaata tgattttaca tctgtacttg ttcgagaact ccaagtataa
    13381 aaaactaagg aattatatag tggcagtata taattaatac ccttagacac acctttttga
    13441 aagtggaaaa aagatgtgta gttctcctcg accacaaatc aaggaggata aaaaatggaa
    13501 aagagaaaag taataattga ttgtgaccca ggaattgatg attctttggc aattcttctg
    13561 gctttaaact caccagagct agaagtaatt ggaattacca catgttgtgg aaatgtccca
    13621 gcaaatatag gtgcagaaaa tgcactaaaa acacttcaaa tgtgttcttc actaaatatt
    13681 ccagtatata taggagaaga agcaccacta aaaagaaaac ttgtaacagc tcaagataca
    13741 catggagaag atggtattgg agaaaacttt tatcaaaagg ttgtaggagc taaagcaaaa
    13801 aatggagcag tggattttat aataaatact ttatataatc atgaaaaagt atcaataata
    13861 gcacttgcac cacttacaaa tatagctaaa gcacttatta aagataagaa agcatttgaa
    13921 aatctcgatg agtttgtatc tatgggagga gcatttagga ttcatggaaa ttgctctcca
    13981 gtagcagagt ttaattattg ggtagaccca catggagcag attatgttta caagaattta
    14041 tctaaaaaaa tccacatggt aggtttagat gtaactagaa aaattgtact tactcctaat
    14101 attattgagt ttataaatag acttgataag aagatggcaa agtatataac tgaaataact
    14161 agattttata ttgatttcca ttgggaacag gagggaataa ttggctgtgt gataaatgac
    14221 cctctagcag tagcatactt tatagataga agtatatgta aaggatttga atcatatgta
    14281 gaagttgtag aagatggaat agctatgggt cagtctatag tggattcttt caatttctat
    14341 aaaaaaaatc ctaatgcaat tgttctaaat gaagttgatg agaagaaatt tatgtacatg
    14401 tttttaaaga ggctttttaa aggttatgaa gacattatag actctgtgga aggagtgata
    14461 tagtgtgaaa agaaaaatat gtgtaaaaac tattacactt atagcttttg gtatttctat
    14521 aaatataata ggcgctttta tagctatggg attaagatta cctgtatact tagattcaat
    14581 aggaactata atgatagctt cacttttagg acctaaatac gctgttgtta caggtgtgtt
    14641 tggaagttta ataagtggaa ttacgtttga tgtgtattct ctctattttg caccagttca
    14701 aatatcaacc ggattacttg ctggaatagc atttaaaaag aattttttaa ggggtttaaa
    14761 aactccacta ggagtacttt tatttgccat tccaacatct ataataagtt caataatttc
    14821 agcattttta tttggaggta tgacctcttc aggttcatca tatatagtgc aaatcttgaa
    14881 agtgttagga ctgggggatg tttttagtgt gtttgtaacc caagtattta ctgattatgg
    14941 agataagctg ttagcagttg ttttagtgaa tttaggatta aatgcagttc caaaaacttt
    15001 aaaggtatca ttgactggag gaaaatagat agaaaatgga tagatatagt gagataacaa
    15061 ataaaaatca aagagaaatt gttctgctta aaggatttcc ttgtatatgg ggaaagtgtt
    15121 ctttttgtga ttatatagat gataattcta atttagaaga agagatgaat aaattaaatc
    15181 taaaggtttt aaaaaacgta actgggaaat atggagttct tgaagtcata aattctggaa
    15241 gctgttttga attacctaag gatactttag aaaaaataaa gtgtattata aaagagaaga
    15301 atataaaaaa attattttta gaaagtcatt ggtcttacaa aaataggctt aaggaaatga
    15361 gagagtattt tgaaattcct gtggtattta aaattggagt tgaaaccttt gacaatgatt
    15421 ttagaaataa tattttaaat aaaaatgcaa attttaagac tccacaagat gtaaaagaat
    15481 attttgattc accttgtatt atggttggaa taaaaggaca aacaaaagag atgatagata
    15541 aagatataga gattatccta aatacttttg aaaaagcgac agtgaatgtt tttataaata
    15601 attcttctag tataaaaaga gatgaagagt tagtgaaatg gtttgttagt aagtataaat
    15661 tcttggatga aaatccaaat atagaagttt tatacaataa tacagacttt ggtgtaggag
    15721 attagcatta atttagttta aatttaaaat tgaaaagttt cttatgtttt tgaaaaagct
    15781 tctaatagtt agaagctttt tttgtagagt tttatgttac aataagaaaa aaggaattaa
    15841 ggagcaatta aatgatgttt gataggggaa aatggaataa attggattat aatgaacttt
    15901 tagaatatat gatgtctata caagatataa aatatagaga ttttaataaa aagcttatac
    15961 ctggaacaga aaatataata ggtattagag ttcctaattt aagaaagtta tcaaaagaaa
    16021 taagccaagg gaattggaag gaatttttag aagtagcaca ggatacatac tatgaagaag
    16081 ttaggctaca aggtatggta attggcaata taaatagtaa ttttgaagaa actttatact
    16141 atgtaaaaag atttatacct aaaatcgata attggtcagt ttgcgatgga ttttgttctg
    16201 atttaaagtc tatgaaaaaa tataaagaaa atatgtatga tatacttaaa aaatatgttt
    16261 attcaaagaa tccatgggaa attagatttg cattagttat gtttttaata tattatgttg
    16321 atgataaaca tattaaagaa atatttgaat actgtaataa tatacaaagt gaagaatatt
    16381 atgttaaaat gggtatggca tggttgctat caatttgttt tattaaatgt gaagaggaaa
    16441 cttttctcta tataaaaaat aataatttag atgatttcac ttataataaa atgctacaaa
    16501 aaataattga atcaaataga gtagatttag aaaagaagaa tataataaga agtatgaaaa
    16561 gaaagacaag aagatgttga cggaggaata ttaatgaata acaatgaaga cagaattgac
    16621 aaatttttag aacttcaaag caaaggattt aaatttgcag agatagctca aaatctaaag
    16681 attagtcaaa gtactttaag aactttttta aataaaaaag gatataagtc agaaaaaggt
    16741 aaatacatat taaaagacga attaaattat aataaaagtt tggataatag aaacttggaa
    16801 gaagagaaag ctaaggagta tgaaaaaagt aaaaagaata ctataagtaa tagaaaaaaa
    16861 gtaagcacca aaaaaaagat ttctaatgaa aaggctttaa gtaaaagtgt tgaacaaatt
    16921 gagtttaatg atacaggttt aaaaaatgca aagccaaaac aaaatattaa gcctaagaaa
    16981 gatagaaaaa taaatataac tcaagaagat ttagataagc tttgtgaagt atatgattgg
    17041 tatttagaag taaaagatta caatataaag cctaaaaaag tatctaataa aaaagatgta
    17101 catatagatg atgaacacat agatgaatta aaaacaacaa gaatacgtat agataaagaa
    17161 atatggaatg attttgaaag attatgtagt aattcgaatt ttgaaaaaca tcaaatactt
    17221 acacaggcat tgaaagaatt tatgaaaaag tataaaaatc tactataaaa tactactata
    17281 tgaggtgctt aatatgaata aaatagtaaa aaaatcaatt tctctaatga ttatattaac
    17341 aatatttatt tttatgttga cagcatgtga aaaagatgaa cagcctgatt cagttgatat
    17401 tcaaacagaa gataaaaatg agataaaaat agatgaggga aatgcaaaag tattgaatat
    17461 aggaaaatca gaaattataa atatagatga aggtgataaa gtagatacat caacaaaggt
    17521 agaaaataat tcaacattta atatatccaa tgttgaattg atatataatg aatatgatga
    17581 gaataaaaaa attatatctt cggatagtaa ggctttgttg gacatgactt taatgcctgg
    17641 gaaagttgct tacatagaat gtgggcataa aacttttgta aagggtgtag aagtttatgc
    17701 atatgaatat gaggcagagg gtaagattgt gtatgttaat ttaaaagaaa atactattaa
    17761 tataagaaat aataatatta agctagaaaa tagtagtcag tatgaggtgc tatctacatc
    17821 agaacttaaa aaagtaaatg aatcaaatga gggaattacg tatcaagtaa aagtaaaaaa
    17881 ttcatcatca aaagatttag gaaatattat tcttaagaca gcagaagtta atgaaaatgg
    17941 agaatattta acagtaaatc gtgtaccatc atataagatt ttaaagcctt cagaagagac
    18001 agatatagat atattgtgtt caacaaaggc aaaaagtgtt gaaatagtgg gatatacgta
    18061 tgatgatata aaagaaaaag ccaatgtgga tattgactta aaatctcata aagttaagat
    18121 agacaaataa aggtagggga tacttatgaa ggttttaata gttgaagata ataagatact
    18181 tttagaaagt gtagtagaag aacttagcaa gcattttgaa actgaaaagt gtgaagatgg
    18241 agaagaagct ttatacttaa taaatcaaaa tatatatgat ttagtcattt tagacttaat
    18301 gcttcctaat ataaatggat ttgatatcct aaagaaaatg agaattaata atatagatac
    18361 acctgtactt atattgacag caaaagaaac attagatgac aaagtagaag catttactat
    18421 aggagctaat gattatttga caaaaccttt ttatatggaa gagttagtag ctagggtata
    18481 cgctatatta aggactaatg gaaagataaa agaaagaaac ggattagaat ttaaatcttt
    18541 atatttagat acactagaaa aaagagtgta tattgaaaaa gaagaaataa aacttcaaaa
    18601 caaacagttt aacttgcttg agtattttgt attaaataaa ggttcaattt tattaaaaga
    18661 gcagatttat gatagaatat ggggaattga ttcagatgca actattgaaa tagtggaagt
    18721 atatgtaagt aatctaagaa aaaagctaag taaatatgga tatgataaat atattaaaac
    18781 taaacgtaag gtaggatata tattcgatga taaataagaa tgtatttacc agtactaaaa
    18841 atcatttaat aaaaatgtat attattgtag taggtagttt tttaataatc ttttctatat
    18901 ttatatactc atattttagg ggacttacat atagtggaat tgatagtgag ataaatgatg
    18961 aacttgaata tatagtctct caatttaaaa gaacttcatt tttgaaccca ataagactca
    19021 aagatcctaa agatatggtg tatgtatatg aagatggaag gataagttac tatactcaaa
    19081 atgaatattt tgatgagtta cttccagata gaagactaga taaaaaaaat tcgtttttta
    19141 aatacacaga aaatggatat acttttagag aattaaatgt agatgtaggt agataccaaa
    19201 tacagataat tagaaatata gattctgaga tgaattcttt aagacagctt acatctgttc
    19261 ttataattgg aatattaatt tctgtaataa ttacttactt tgtggctgta tatctcacta
    19321 gaaaagcttt aattccaata gaaacagcat ggaaaaatca agctaagttt atacaagatg
    19381 cttctcatga attaagaaca ccaataacaa tagtttcatc aaaattagaa agtatgttaa
    19441 aatccccaga aagtacagta aatgatgaag ttgaaacaat agctactgca atgaaggaaa
    19501 ctagaagact taaaaaaatg ataactgatt tattgtctct tactaaagag gactctattg
    19561 ttaaagttaa tttagaagaa atagatttag aaaagttatt ggaagaaata tcagaagact
    19621 atattgacat tgctgagttt caggaaaaaa gattcgtgtt taattctaaa ctgaagaata
    19681 aagttataat aacagataaa aataaattaa gacaacttat attaattttc attgataatg
    19741 cctttaagta tacaaaattg ggtgatgaga tagcattaga attgaaagaa gatatagagg
    19801 atgaggtaac tttacttata agtgatactg gtataggcat aaaaaaagaa gagatacctc
    19861 ttatatttga tagatttttt agaagtgaaa atgtaagaaa taaagattta gaaggttctg
    19921 gaataggact ttcaatagct cgcatgatta gtttaaactt atctattgat ataaatgtaa
    19981 cttctgatgt agatattgga actacatttg aattgtcaat accaaaaaag ttaaaataat
    20041 aaaaatataa aaaattgttt ttagaaatga agaatgggta tactaattag tataaaatat
    20101 aaaaagacct tataaaagta aatttatatt tataaatttc atagtataat tatataggga
    20161 taataaagtt taataggagg atttaaaaat ggcaaaagtt ataaatacat ctgaatttag
    20221 aagtagtgtt gaaggtagta agggagtagt tgtagttgat ttctttgcaa cttggtgtgg
    20281 accttgtaac atgttgggac ctgtatttgc agaattaggt gaagagatga aggataaagc
    20341 tagatttgta aaagttgata tagatgagag tttagaaata gctcaacaat tcaatgtatc
    20401 tacagtacca actatgatta tatttaaaga tggaaaacca gtagaaactt taattggatt
    20461 catgccaaag aacaaaattg aaatgcaagt aaaatcatat ttataaaaaa tgggtgagta
    20521 ttatgagata tgatatagct ataatcggca gtggtccagc tggattgtct gctgctataa
    20581 atgcaaaaat aagaaataaa acaattatca tgtttggtaa tgataattta agtaataagc
    20641 ttgttaaagc tccttcaata gataattatt taggttttta tgatataagt ggtgatgaat
    20701 taaaagacaa gtttaaatca catatagata gtatggatat ttcaattgaa aataaaagaa
    20761 taaataatat ttatgctatg ggagaatact ttacaataat gtctggaaat gatatgtatg
    20821 aagctactac tgtaatcctt gcaactgggg tagagtatac tagaccaatc aagggtgaag
    20881 aagaatttct aggaagaggt gtgggctact gtgctacatg tgatgcacca ctttatagaa
    20941 ataaaaaggt agcagttata ggatataatg aagaatctaa agaagaagca aattttttaa
    21001 gtgaactcac ttcaaagact tattttatac ctatgtacaa aaaagataat cttatgagaa
    21061 gttcagataa cctagatgat tctattgaag ttatacatga cagaccagta cagatagatg
    21121 gagataaact tgtaaacaaa gtatctttta aagaaaacca cattgaagtt gatggagtat
    21181 tcgttataaa agatagtacg gctccaagtg cattggttcc tggaatagag attgatggca
    21241 ttcatattaa agttgacaat aatatgaaga ctagtataga tggatgcttt gctgctggag
    21301 attgtgttgg aaaaccctat tcttatataa aagcagctgg tcaagggcaa atagcagctt
    21361 taaatgctgt ttactattta gataaattaa agagggctta atatttatat tgattaactt
    21421 tttaaagata tttataaaaa actgtcttga aataatttta ttatttcaag acagtttttt
    21481 atttttaagt tattaataaa agtattttaa aatctatatg taattacttt tattaataaa
    21541 actcaaagtt atattagtaa aaattggaat tatttataat atactccaaa atttaaaaat
    21601 aatggttgaa aaatctaatt aagagtacta taatttaatt aagtaattac ttaatcaaaa
    21661 tgaggtactt atggaaaact tggttaaaat atttaaagca ttgagtgatg aaactagact
    21721 taacatactt atattagtat ccaagagaaa tatatgtcaa aaggggattt ctaaatatct
    21781 agggatttca gattctgctg tttcacaaca tataaaaata ttaaaagatg ttgggataat
    21841 aacaggatat aaagaaggat actatgtttt atatcatatt aataaagaat catttaatat
    21901 atgtgtagat tttataaatt ctatgttaag taattctagt gaaagcttta tagatgtatt
    21961 tgatgtaaat acaatacatc taggatgcag taaagaatgt aaatctataa aaaaatgttg
    22021 taagagaagg gagaaataat aatgaaagta tgtataccag tagaggagaa taaaggattg
    22081 gatagtaaac catatggaca ttttggttct gctccaattt ttgttgtgtg tgatttagaa
    22141 agtggagaag ttaaatcttt agataatgga gatttagatc atgaacatgg aaaatgtcaa
    22201 ccattaaaag cattgtcagg gacagctgta gatgcagtag ttgttggagg aataggacaa
    22261 ggagctataa ttaaattaaa tggaatggga ataaaagttt acagagcaga aggtgatact
    22321 ataagtgcta atttagactt acttaaaaat ggaaaattag tagaatttcc atcagaccat
    22381 acttgctcac atgacggatg tggacatcat taaaaaaaaa cagctgatga aatatatact
    22441 tcatcagcta ttttttcttt taataaatac gattttattc ttttaaaacc aaaatttaga
    22501 tttttatgtt ttttgtagta tccttaataa tatttcaagt ttacaagttt actactttta
    22561 gatttttttt gtatgttttt ctatatagtc aatatcattt aatatgtcat tgagttcttt
    22621 attaagtgtt tttaaatcat caccatctac attgtagttt aaaaatagtt cctctacatt
    22681 atcaatgata gaattgactt ttctagtaac ttcaacaaat gtcttaaagt tactactatt
    22741 tttagcattt agaaattttt ttaaatcctt tgatataaat gatactattt catattcatc
    22801 attaaataga cctctaccaa taggatatgg ttcaattctc tgtaaaaaat attggtcttt
    22861 agcattaata ttataagtat aagatatttc ccaaccgtct cctaaatcaa acttgataaa
    22921 atataatgta ctacttactt ttgatattct tgtggcacca agctgtctta aaagaacttc
    22981 aatcgaatca ccttgaacag tattaatatt catatataca catccccttt agtattatta
    23041 tactatattt tttaaaattt tataattaaa taaacagtag atataataat agatataatc
    23101 ataagtggaa aacctatttt gaaatactcc ttaaaagaga taggatgacc gtgtttatta
    23161 cctatacctg ctagtacaac attagcagat gctcctatta gtgttccatt tcctccaaga
    23221 caagctccaa gagatgttgc ccaccatagt ggcattacat caataccttc agcttgcata
    23281 gtcaaaataa gaggaattag tgttgcaaca aatggaatat tatctaagaa agaagagact
    23341 atagctgaca accataatat caacaacatt gtaaatacaa gatgtccttc tgtaagtcca
    23401 atcaatgctt gagccaattt gtttattatc ccaacttcta ctaatccacc aactactaca
    23461 aataatccca taaagaataa aattgtagac cattcaatac ctgccataat ttcatctaca
    23521 tcttgttttc ctattaaaag cattatagat gctcctgtca gtgctacaac agaagaatct
    23581 atgtggattg tactgtgaaa cataaaacca aaaagtatga atgctattaa tataaggctt
    23641 tttataagta gaggtttatc tttaacagat tttttttcat ctagttttaa tattgcattt
    23701 ttagctcttt cattcacaac aagttctttt ccataaataa atctaaagca tattatagtt
    23761 atagcaagta ttactataac agcaggacct aaatttatta caaaatccat aaaactaaga
    23821 ttggcagcac taccaatcat aatatttgga gggtctccta taagagtagc tgttcctcct
    23881 atatttgaag ctaaaatctg tgttattaaa aatggaactg gattaagtcc taatatttgt
    23941 gtaataacta tagtcattgg tccaataagt aagacggttg taacattatc taatacagct
    24001 gataaaatag ctgttataat agcaaaacaa atcattatct tccatgggtc acctttggct
    24061 ttctttgcag tccagatagc tatatattca aataaccccg agtttttgac aacagctaca
    24121 aatagcatca taccaactaa tacaccaata gtattgaaat ctatatggct taatccttca
    24181 tcaagtgtaa gtatattgaa tattatcatt aatagtgcac caccaacagc tgctatggat
    24241 ctgtttacct tttctgtaat aatagctgcc ataactatta aaaatataca tatagctatt
    24301 atttgttgaa attccataat ataagtacct ccatttgtat tattttgtgc ctaatgctag
    24361 tactatatat agtattactt ttttattgtt ttttcaatgg atgtatgaaa gtatattatt
    24421 taacaaagtt tttggaaaat tgacagaatt taaagaaaat ttttgttatt taaataaatt
    24481 ttaaaattat tccattgata ataatattaa acgacaaacg aaaaaatata cccttt
//
LOCUS       DAMKNB010000052        24176 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.054, whole genome shotgun sequence.
ACCESSION   DAMKNB010000052 DAMKNB010000000
VERSION     DAMKNB010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 24176)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24176)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24176
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.054"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            20..871
                     /locus_tag="PC494_002376"
     CDS             20..871
                     /locus_tag="PC494_002376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfurtransferase"
                     /protein_id="HDF3912872.1"
                     /translation="MKNIISAKELISKLEKNDNLVVIDCRFDLINRTYGIDSYKKGHI
                     KGSFILDIDKDLSSPTKEHGGKNPLQDPLILKEKLEKMGVDNDTTIVTYDDGDLNGAC
                     RLFFQLKHLGLKNVYVLDGGITSFVKEGGELEEKVNIPSCTGKEIRPNINNDLVVPME
                     YVKSKLYKKDTVIIDCRANERYQGLVEPAYSKAGHIPSAKNYFCKDLIKSDFENGSLK
                     DIEFLKKFFKDLNNYDEVILSCGSGISACVNSLALRELDIPHKIYIGSFSDWISYDDN
                     EIKTGQE"
     gene            complement(1004..2617)
                     /gene="ggt"
                     /locus_tag="PC494_002377"
     CDS             complement(1004..2617)
                     /gene="ggt"
                     /locus_tag="PC494_002377"
                     /EC_number="2.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyltransferase"
                     /protein_id="HDF3912873.1"
                     /translation="MKFNAYQHKYSSIRNVVYAKNGAVATSTPLASQAGLEILKKGGN
                     AVDAAVATAATLAVVEPTSNGIGGDAYALVWIEEEKRLYGLNSSGFAPENMELKNYNN
                     MKEMPKYGFGAVTVPGIPAAWSELNKKYGKLSLMECLSPAINYAREGYVVSPNVAKVW
                     KKSYELYEKELIGEEFKPWFDTFSKDGKAPEAGDIFICEEQASTLEEIANTQAESFYR
                     GRLADKIDEYSKKFNGAIRKSDLECFYPTWVEPISTEYKGYKIFEIPPNGHGITVLMA
                     LNILKELELEGNIENVEDIHKIIESLKLAFADSKTYVTDIEHMKVKIQELLSQEYAKK
                     RSLLIDNKEALYPTAGEPYCGGTVYLCTADKDGNMVSYIQSNYINFGSGIVIPRTGIA
                     LHSRGNNFNLDPKHHNVVKPFKKPYHTIIPGFLGKEDKAIGPFGVMGAFMQPQGHIQV
                     LTNMIDFGLNPQEALDAPRWQWIKGKEIEVEPEMPKHIIDSLIEKGHEIKVIHDTVDM
                     GRGQIIFKTEQESYICGTESRCDGHIAVY"
     gene            complement(2842..4779)
                     /locus_tag="PC494_002378"
     CDS             complement(2842..4779)
                     /locus_tag="PC494_002378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF3912874.1"
                     /translation="MTLFRIAMQNVKNSFFNYLMYFISIVFSVFVFFSFKSIEYNEAL
                     SSLGEKTRMSINTSSIVIVVFVFLFIYYSNSFFFNRRRREVGTYSLLGMRKNQIGKIF
                     LYETFLMGIVAILIGIFLGLLFSKLMTMMLVKLMNEMIVVNMNLSIKALVQTLAVFLI
                     IFIVIGIRNTIVIRNKRIIELFNKYPEKYKFKKFIKLKCVLGVLLIAISYLMSISYFI
                     AENIMLSVFILVTIIPGTFLFFSSTMYMIIDAVKKRKSFYYKGQNLIAFSELGFKLKS
                     NSSVLAVIAILIATSVTMLGFTISLYYDIDRNISENYKYSYTINLGNSYVNNEIDKLL
                     YKYKKDNKIIFDKTIELIDKDINIEMYYKNGNSYIEDRTSVDIIRESDFKKLRQYQNN
                     NYEELTSKESVYYVSDSYKKIFFKDFEIEKINLHIKDANEYDINLFKVQKSILEPEIN
                     SQATFDLIVVKDDVFNQLKLHGNSRLIRLIDIKNEKKELDLTLKLKNIVSENMKFTYP
                     FNFTSSIESYNNLIKLSGLMLFIGIFLSVVFLLCTGSIILFKQLSNIYDDKERYIMLI
                     KLGANNKDIEKIISKQLKVIFLMPLVVGTVHNLFAMSIAQKFIPRSLLVPIIITLVIY
                     FIGYFIYYFLTLKYALNMIKE"
     gene            complement(4766..5533)
                     /locus_tag="PC494_002379"
     CDS             complement(4766..5533)
                     /locus_tag="PC494_002379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003722224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF3912875.1"
                     /translation="MEEILSVENIKKEYGRKGSKHEALRGITFKVYKGEFVGIMGSSG
                     AGKSTLLNIISTIDLPSSGDIYINGKNTIKMKQNELADFRRDNLGFVFQDSNLLDTLT
                     IKENIMLPLSLKNERVSVIENRIKEISKELNIESILDKYPGEVSGGQKQRGAVCRAIA
                     TKPSLVLADEPTGALDSKSARDLLNCLLKLNKDSNKTILMVTHDAISASFCNRILFIK
                     DGIIFTEIVKGESNREFYNKIVNTVSLIGGVNKNDFI"
     gene            5821..6495
                     /locus_tag="PC494_002380"
     CDS             5821..6495
                     /locus_tag="PC494_002380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF3912876.1"
                     /translation="MFKIMVVEDDVSLKNIIAKCLTKWGHDVHQIENLENIIEEFKNY
                     NPELVLLDINLPFYDGFHWCNEIRKISKVPIIFISSRNSNMDVIMGVNLGADDYIQKP
                     FSVDVLVAKVNALLRRTYNFVDNNSNQIIHNGVTLDLSTATINYEDNTIELTKNEIKI
                     LHELMKYKGQIVSRNKLMKKLWDNDWFVDDNTLTVNVNRIRSKLNEIGLEDFIETKRG
                     LGYIIS"
     gene            6519..7523
                     /locus_tag="PC494_002381"
     CDS             6519..7523
                     /locus_tag="PC494_002381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF3912877.1"
                     /translation="MSFKDFLKDKLGFLVYNFTFLIFTVSVIIFSPVDVFLTDTILYI
                     LVVNVVFLFLYLFISYIKKNKFLDKIKNDTFKINMNDIELARCKNEEKIYLNIIKNHQ
                     YQCNNIINNNIEKFEENKEILNMWVHDVKIPIAIIKLILEQNENLIDEKISDDIDSEI
                     FRIENSVEKILYLSRLEDFHKDFLIQEVNIEKIIRNIIKKYSKYFISKKIILDLNNLN
                     FKVLSDEKWLYFIFEQLLSNSLKYSSLGDNISIYCKRTKNYLQLRVEDTGCGIKKEDL
                     NRIFNKGFTGNNGRNNSKSTGLGLYLVKELCDKLGHKIDVDSEYNQYTKFTITFKCDL
                     "
     gene            7635..8864
                     /locus_tag="PC494_002382"
     CDS             7635..8864
                     /locus_tag="PC494_002382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HDF3912878.1"
                     /translation="MSFLKKFKNKRFRNNSFKSNNFRNSSFGSSGFKSKNKGFKNNPF
                     KNKRFKIYAGIAVIILLILGVLAYVDSKNTELQANENFIETYTIPENEKIFINGMVVP
                     KQTKDFNISGDYELSDVNVTNGQKVNQGDLLFTAKNPTIIAEIDSLKSQLSQYKKQKI
                     SLSDIAENKDAIASINAQITALNSQIASLDKKAYDRVTAPFDGTVYLNDQTGNPDQPV
                     SFMTIQGLEFYMKGQASEQDLPKMKIDQMVNILVFSTDQKLTGRISFISDKPSTPNTE
                     MGAQQNTLSYYDINIAFDNQEGLVNGFHLQASLEVANSSFKIPASCVLKDNKHSYVFK
                     DLDGILKKQIVDVASQNDDFAVVRGGLEQGDIIIKHPTKEMKEGDPVQGDGVTAGSNN
                     GDTTPNKKVEEVTMDVN"
     gene            8872..9546
                     /locus_tag="PC494_002383"
     CDS             8872..9546
                     /locus_tag="PC494_002383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF3912879.1"
                     /translation="MLIKLENIQKYYKVGKDELHVLKSLNLEIESGEFVMIMGKSGSG
                     KTTLLNILGFLDVFDEGRYIFDGTDVTNLSENERSVFRNINIGFVFQQFNLIETLNVY
                     QNVELPLIYNKALKKSNREEIVKDKLSSVGLLDKLKQKPLQLSGGQQQRVAIARCLAN
                     DPQIIFADEPTGALDSETSREIMELLTRLNKQGKTIIMVTHDQDLTKYATKVIRLKDG
                     VFTSEV"
     gene            9549..10781
                     /locus_tag="PC494_002384"
     CDS             9549..10781
                     /locus_tag="PC494_002384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF3912880.1"
                     /translation="MSLLKNSLANLKGHKLRVFVALLWIIIGITSVILVSSIGNGFQK
                     EIKKSVNNVNPNKTTISFESADNTGLTDDMSIFLKPFNAKDLEELSFVEGVERIAPSR
                     DGFNLDSVYSSQASFDKKTTYVDVGPVKKDSKINLICGRDFSLDDEKRKVILLTLQST
                     SEIFENPEDALGHGININGTIFEIIGVLDDSQQNQAGGFFGGYQDMQFTTSLVPKKAF
                     DTLMSQNSYSNEIYQLDLVSSKGYNVNEVANNVIAKLYEMHPGINGSYTTPDPTEQTA
                     YLESINSNVNKYVSIITVVAMFVGGIGVMNIMYVSVMERQREIGIRRAIGAKPRSILF
                     QFLVEAVFITVCGGILGTIVGFAATNYVSKYIGFEAIPSLNSLFYAIVATILTGVVFG
                     LIPAFKASKLDPIKAIYK"
     gene            complement(11067..12332)
                     /locus_tag="PC494_002385"
     CDS             complement(11067..12332)
                     /locus_tag="PC494_002385"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HDF3912881.1"
                     /translation="MILIKNGRVIDPKSQRDENIDLIIKENKIYKIGKFDESDEYEKI
                     IDASGNVVAPGLVDVHVHFRDPGFTYKEDIESGAKSAARGGFTTVICMANTNPIVDNE
                     DTFNYVKEKSKNACINVLQAAAITKGFEGKELVDMEALKKAGVPGFTDDGLPLMDSNL
                     IMEAMIKAKELDVPLSFHEEDPSLVGNPGVNAGKVASELGLKGASSVAEDVMVARDCM
                     LALKTGAKVDIQHISSGVSVDMVRFAKYLGANVVAEASPHHFTLTEEDVLEFGTNAKM
                     NPPLRSKWDRDKIIEGLNDGTIEIIATDHAPHSKEEKDREFIKAPSGIIGLETSLALG
                     ITNLVHKNHLSMMQLIEKMSINPAKLYNLNIGFIEEGAVADIVIFNPEEEWTVESFVS
                     KADNSPFKGKSLYGKVNYTICNGEIVYNA"
     gene            complement(12385..13533)
                     /locus_tag="PC494_002386"
     CDS             complement(12385..13533)
                     /locus_tag="PC494_002386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF362 domain-containing protein"
                     /protein_id="HDF3912882.1"
                     /translation="MKSVSVRSCKTYNYEEVKLSIEKNLEDIGGIDKFVKKGSKVLIK
                     PNLLMKKKPEEATTTHPMVVKVVCEKLLELNCDITIADSPGGPYNQSSLKSIYKASGI
                     EEVANELGIKLNYDVSDVKIHSEKAHVLKYMDIIKPIVDSDYIINLCKLKTHIMATFT
                     GGTKNLYGCIAGLKKAEIHYRFPTEELFCENVLLDICDYIKPTLTIMDGIVGMEGDGP
                     SAGTTREIGVLLASQNPYAIDVVACKIISLLPNRVATIRGAIKRGYIQEDFSDIEILG
                     EDIKDLIIKNYKIPNVSKDLRLFSVKLPKFLNEPISKLITPKPVVRFQDCIKCGKCKE
                     ACPASTIEIGTKGAIIDLSKCIRCYCCHELCPKKAIDVKRNFVFKYVK"
     gene            complement(13633..14178)
                     /locus_tag="PC494_002387"
     CDS             complement(13633..14178)
                     /locus_tag="PC494_002387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH peroxidase"
                     /protein_id="HDF3912883.1"
                     /translation="MKKFVCTVCGYIHEGDAAPAQCPVCKVGADKFEEMKGEMVWADE
                     HRIGVAQGVDAEIIEGLRANFTGECTEVGMYLAMSRQADREGYPEVAEAYKRIAFEEA
                     EHAAKFAELLGEVVVADTKENLRVRVDAEYGATDGKLKLAKRAKELGLDAIHDTVHEM
                     CKDEARHGKAFLGLLNRHFGK"
     gene            complement(14401..15345)
                     /locus_tag="PC494_002388"
     CDS             complement(14401..15345)
                     /locus_tag="PC494_002388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HDF3912884.1"
                     /translation="MQKNKKEGALLKKYFGEIGLIFIAIIWGSGFVATQFALDGGLTP
                     LQIITLRFFLAAIIMNLLFFKQIRANMGKKLLKAGGILGIFLFLAFTVQTIGLMYTTP
                     SKNAFITAANVVIVPFIGFILYRRKLDKIGIISSLVALIGIGILSLEADFSINFGDFL
                     TLICSFGFAFHIFFTSEFAKDNNPMALTAIQFTVAFLMSVVVQTFAGQLKMEAELSGY
                     MGTMYLAVFSTTIGFLFQTICQKRVDGTRTAIILSTEAVFGTIFSIIILKELITAKLV
                     IGSILIFVAIITAETKLSFLKSKKVKLKDSEESSLESI"
     gene            15731..16612
                     /locus_tag="PC494_002389"
     CDS             15731..16612
                     /locus_tag="PC494_002389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase"
                     /protein_id="HDF3912885.1"
                     /translation="MVKKRKKKTVALTILVVIVIGIFSMAWADMSRKKEMKETQERLK
                     AERLEKERIEKEKNEPIIGAKKEAVKEYGYDAKIVWDKLNKYDYSNNGEKIVFLTFDD
                     GPSTTNTPQVLDILKRHGVRGTFFIKGDSLERKGANEILKRTFDEGNAIAHHSYTHDY
                     KKLYPNRSLNLDTFVNELNKTDEAMKKVLGKNFSSNVVRCPGGYMSWKNMEPLGNYLK
                     EKNMASIDWNALNADAEGKKKNAQELFEHAKKSSEGKEMVVLLMHDTYGKQETVNALD
                     QIITYFKDNGYQFKILI"
     gene            complement(16673..17881)
                     /locus_tag="PC494_002390"
     CDS             complement(16673..17881)
                     /locus_tag="PC494_002390"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HDF3912886.1"
                     /translation="MKSIDEQMRIIMKGVDDLIDEKELREKLIKSEKEGKPMIVKLGL
                     DPSAPDIHLGHTVVLRKMKQLQDLGHQIVIIIGDFTGKIGDPTGKSKARKALTTEQVL
                     ANAKTYEEQIFKVLDKEKTIVRFNSEWLAKLNFEDVIKLAATITVARMLEREDFKKRY
                     EGQMPISVHEFFYPLMQAYDSIALEADIELGGTDQRFNLLMGRSLQREFGMESQIVIM
                     MPLIEGLDGKEKMSKSLGNYIGIDEEAGIMYQKSMEIPDELIIKYYNLVTDVHPDEVN
                     KIESQLKEGSVNPRDIKMDLAREIVTLYHGEESAKEAEERFKSVFQKGQIPEDIQTIQ
                     VKEDGFDLIEVLVSNEIVKSKSEVRRLASQGGVKVNGEKVEDLSTIVKESELVVQIGK
                     KKFVKIELVK"
     misc_binding    complement(17954..18206)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(18358..19347)
                     /locus_tag="PC494_002391"
     CDS             complement(18358..19347)
                     /locus_tag="PC494_002391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2232 domain-containing protein"
                     /protein_id="HDF3912887.1"
                     /translation="MIYGGSVLNTTKKLTEAALLSSLFIVVTIIAVSTGFGYAIYLDF
                     IVPVFFCIICLKCDLKYTILSGITSLLIISLVLGNLGTAIWASQSVLLGIMCGYLINK
                     PTMVMDDLVYGSVFGVIVMVFIDIYASTLIGYSFMKEFQGYSKWIYFNGYTNFIYYLM
                     IALFPFGMVFCIYLLSLILGNKLHILDSNSLKKFLIFKNFRNLNQFLCCSKKAFYICV
                     SYLAIFEVLKLLNVKVDSVYLKTIFISITYISVYFIIRDSCMSLQNFIIAKFRKLLYA
                     RILFLIIILLLFFIFDVTVIGLIIINAFLNKKINIRLSQSNIVNKQINLLIEK"
     gene            19499..19939
                     /locus_tag="PC494_002392"
     CDS             19499..19939
                     /locus_tag="PC494_002392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDF3912888.1"
                     /translation="MFKIKHFNDLSLDEFYEIAKSRYEVFACEQKIFSLNDYDDIDKS
                     SYHIFLKENGLICAYARIIPKEYSSYNDVSIGRVLVLSSHRRKGLAKQMMDCAIDFIK
                     VNLHENNITLSAQTYIKNLYLSCGFKEISEVYDEAGIEHIKMRL"
     gene            20266..20493
                     /locus_tag="PC494_002393"
     CDS             20266..20493
                     /locus_tag="PC494_002393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HDF3912889.1"
                     /translation="MKNLNDIQVKKTVKVEDILSSGNLRERMLALGLTRGAVIDVVRK
                     GPKNNLTVYKIRGSKIALRQEESSLILVSDI"
     gene            20519..22639
                     /gene="feoB"
                     /locus_tag="PC494_002394"
     CDS             20519..22639
                     /gene="feoB"
                     /locus_tag="PC494_002394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein B"
                     /protein_id="HDF3912890.1"
                     /translation="MGLTHNSTKMSSLKDMFDIDNKEDQFVIALAGNPNTGKSTVFNH
                     LTGLRQHTGNWPGKTVATARGNFKYKNTEYALIDLPGTYSLFALSQEEIVARDFICFG
                     NPDAVIVVCDATCLERNLNLVFQVMELTDKVILCINLIDEARKKGITIDKKLLEDSLG
                     IPVILTAARNGSGMDELLDTLNDVSFDKYKLNNKPVRYNENIENVVKSIQPELDNIIP
                     GINSRWLGLRLIDGDESIFESMSNYIDKDSIDAINEVKKKIPDNINKQKIRDEFTKIN
                     YDYAKKLSDECCSNVAKKSTDREEKVDKILTSKIFGLPIMLLLLGTILWITIEGANYP
                     STLLSNLLLGFEPSISGILNSINCPSWLNDMLVLGLYRTLAWVISVMLPPMAIFFPLF
                     TLLEDFGYLPRVAFNLDHLFKKACAHGKQCLTMCMGFGCNAAGVIGCRIIDSPRERLI
                     AILTNNFVPCNGRFPTLIAISTIFFSSVITNSFVSSVATALCITLLIILGVIITLLVS
                     YTLSKTLLKGVPSTFTLELPPYRVPQIGRTLYTSIIDRTIFVLGRAVMVAIPAGVITW
                     IFANIYIGDLSILSHVANFLDPLAKLIGLDGFILLAFILGFPANEIVVPILLMAYLAT
                     GSMIELDSFSALGQVLREHGWTYLTALNVMLFSLLHWPCATTLLTIKKETGSLKWTAL
                     GFLMPTILAFVVCFLTTTVYNLFI"
     gene            complement(22772..23590)
                     /locus_tag="PC494_002395"
     CDS             complement(22772..23590)
                     /locus_tag="PC494_002395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HDF3912891.1"
                     /translation="MEKQYFTTGEFAKLCGISKQTLIFYDKIGIFSPEYKDKNNYRYY
                     SVYQYDTLDILQSLREIGMSLEEIKEYIQNRTPQLCVKMLKEEEKKIREKIKKLRKIS
                     SKMQNRINITVEGISKMNSEEIYISKKFEEYLVLSSDLSNMSNSDFMMELIDFTNYCK
                     SKNLYQGYELGVIVSNENIKNGDYLSISSFYLKIDKKIKDKKLYVKPEGMYACIKHIG
                     KYEDSYKSYEKLKKYIYENEYKIVGNSYEESILDFFCESNEDNYMTEISIQVSR"
     gene            23797..24081
                     /locus_tag="PC494_002396"
                     /pseudo
     CDS             23797..24081
                     /locus_tag="PC494_002396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889354.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT         8499 a         3648 c         3065 g         8964 t
ORIGIN      
        1 aacacaggag gtacattctt tgaaaaacat tatttcagca aaagaactta tatcaaaact
       61 agaaaaaaat gataatctag ttgtaataga ttgtagattt gatcttatca atagaactta
      121 tggtattgat tcttataaaa aaggacacat caaaggcagt tttatcttag atatagacaa
      181 ggatttatca tctcctacaa aagaacatgg tggtaaaaat cctttacaag accctttaat
      241 actaaaagaa aaattagaaa aaatgggtgt tgataacgac actacgattg taacttatga
      301 tgatggagat ttaaatggag cttgcagatt atttttccaa ttaaaacatt tggggcttaa
      361 aaatgtctat gtactagatg ggggaataac atctttcgta aaggaaggtg gagaattaga
      421 agagaaagtg aatataccaa gttgtacagg taaggaaatt agaccaaata taaacaatga
      481 tttagttgtt ccaatggaat atgttaagtc taaattatac aaaaaagata ctgtaataat
      541 agattgtcgt gctaatgaga gataccaggg tttagttgaa cctgcttact caaaagctgg
      601 tcatatacca agtgcaaaaa attatttttg taaggattta ataaaaagtg actttgaaaa
      661 tggctcactt aaagatatag aatttttaaa aaaattcttt aaagatttaa ataattatga
      721 tgaagtaatt ttatcttgtg gttcagggat atctgcttgt gttaacagtc ttgctcttag
      781 agaactggat atacctcaca agatttatat tggtagcttt agcgactgga ttagttatga
      841 tgacaatgaa atcaaaactg gtcaagaata aggctcataa tctatataaa atcagcatat
      901 gatagcttaa attttgtaaa ggcgtcagtc attgtagact ttcgccttta cttattattt
      961 catatactct ttaaatttat tatatatatt ttagttgata atattaataa actgcaatat
     1021 gaccatcaca tcttgattcc gtcccacaaa tataactttc ctgttctgtt ttaaatatta
     1081 tttgacctcg tcccatgtcg acagtatcat gaattacttt tatttcatga cccttttcaa
     1141 ttaatgaatc tattatatgc tttggcatct ctggttcaac ttctatttct tttcctttta
     1201 tccactgcca tcttggagca tctagcgcct cttgtggatt taatccaaaa tcaatcatat
     1261 ttgttaacac ctgaatatgt ccttgtggtt gcataaaagc tcccattaca ccaaatggac
     1321 ctattgcttt atcttcttta cctaaaaatc caggtattat agtatgataa ggttttttaa
     1381 atggttttac tacattgtgg tgtttagggt ctaaattaaa attatttcct ctactatgta
     1441 aagcaatccc agttcttggt atcacaattc ctgaaccaaa atttatgtaa ttgctctgta
     1501 tatatgaaac catatttcca tccttatctg cagtacaaag gtatactgta ccaccacaat
     1561 atggctctcc tgcagttgga tacaaagcct ctttattgtc aattaataaa cttctttttt
     1621 tggcatactc ttggcttagt aattcctgaa tctttacctt catatgctct atatcagtta
     1681 catatgtttt agaatctgca aaagctaatt ttaaactctc tataatttta tgtatgtctt
     1741 ctacattttc tatatttcct tctaattcca attcttttaa tatgttaagt gccattaaaa
     1801 ctgttattcc atgaccattt ggtgggattt caaatatttt atatccctta tattctgtac
     1861 ttataggttc tacccatgtt ggataaaaac actctaagtc actctttctt atagccccat
     1921 taaatttttt agaatattca tctattttat cagcaagtct tcctctataa aagctttcag
     1981 cctgagtatt tgctatctct tctaatgtac ttgcctgttc ttcacatata aatatatctc
     2041 cagcctctgg ggctttacca tctttagaaa atgtatcaaa ccatggtttg aactcttctc
     2101 caataagttc tttttcatag agttcatatg attttttcca taccttagct acattaggag
     2161 atactacgta tccctctctt gcatagttta tcgctggaga taagcattcc attaagctaa
     2221 gtttaccata ttttttattt aattctgacc aagctgctgg tattccaggt acagttactg
     2281 ctccaaaccc atattttggc atttctttca tattattata attttttaat tccatatttt
     2341 ctggagcaaa gccactagaa tttaaaccat acaatcgttt ttcttcctct atccaaacaa
     2401 gggcatatgc atctcctcca atcccattgc ttgtaggttc tactactgct aatgtggcgg
     2461 ctgttgcaac tgctgcatca acagcatttc cacccttttt tagtatttca agtccagctt
     2521 gagatgctaa tggtgttgat gttgcaactg ctccattttt agcatacacg acatttctta
     2581 ttgatgagta tttatgttgg taggcattaa acttcataaa tttcagctcc tcgtcatttt
     2641 ttatttgata ttctgcttag atttattata taacatcaag taatgtaact gatacaaaat
     2701 gatataaaat atagactttt tcctaacttt aattttattt ttaaataaat atcttaaact
     2761 caattctagt attttctatc tgcacttaaa taagttattt tattcaaaac atatatctaa
     2821 ttcttttaac ttaaaaataa tttattcttt tatcatgttt agagcatatt ttaaagttaa
     2881 aaaataatat ataaaatatc ctataaaata aatgactaga gttatgataa ttggtacaag
     2941 taatgacctt ggtataaact tttgtgctat agacatagca aataaattat gaactgtacc
     3001 tacaactaat ggcattaaaa atataacttt taactgtttt gatattattt tctcaatatc
     3061 tttattattt gctccaagtt ttattaacat aatatatctt tccttatcat catatatatt
     3121 tgataattgt ttaaataaga ttatactacc tgtacataaa agaaatacta cagacaaaaa
     3181 tatgcctata aacagcatta gaccacttaa ttttatcaag ttattataac tttcaatact
     3241 tgatgtaaaa ttaaaaggat aagtaaattt catattttca cttactatat tttttaattt
     3301 taaagtcaaa tccagttctt ttttttcatt ttttatatca attaatctta ttaatctaga
     3361 atttccatgt aattttaact gattaaatac gtcatctttt actacaatta aatcaaacgt
     3421 agcttgtgaa tttatttctg gctccaagat gcttttttgt actttaaaca gatttatatc
     3481 atactcattt gcatctttaa tatgcaagtt tattttttca atctcaaagt ctttaaaaaa
     3541 tatttttttg tatgaatcag aaacatagta cacagattcc tttgaagtta attcttcata
     3601 attgttattc tgatattgtc ttaatttttt aaaatcactt tctctaataa tatctacaga
     3661 cgttctatct tctatataac tatttccatt tttataatac atttcaatat ttatatcttt
     3721 gtctataagt tctattgttt tatcaaagat tatcttatta tcttttttat atttatataa
     3781 taatttgtca atttcgttat ttacataaga atttcctaaa tttatggtat aactgtattt
     3841 ataattttca cttatgttcc tatctatatc gtaataaagt gatatggtaa accctagcat
     3901 agttacactt gtagctatta atattgctat tacagccaat acactactat tgctctttaa
     3961 tttaaatcca agttcagaaa atgcaattaa attctgtccc ttataataaa aactttttct
     4021 cttcttaaca gcatcaataa tcatatacat agttgatgaa aaaaataaaa aagttccagg
     4081 tattattgta actaatataa aaactgaaag cataatattt tcagcaataa aataactaat
     4141 tgacattaaa taagaaatag ctattaataa aacaccaagt acacatttta actttataaa
     4201 ttttttaaac ttatactttt ctggatattt attaaataac tctataattc tcttatttct
     4261 gataactata gtatttctta ttccaataac tataaatatt attaaaaata cagctaatgt
     4321 ctgaactaag gcctttatac ttaagttcat atttactact atcatttcat tcattaattt
     4381 tacaagcatc atagtcataa gctttgaaaa taacagtcct aaaaatatac ctattagtat
     4441 tgcaactata cccatcaaaa aagtttcata taaaaatatt tttcctatct gatttttcct
     4501 cattccaagt aaactataag ttcctacttc tcgcctacgt ctattgaaaa aaaatgagtt
     4561 tgaataatat ataaataaaa atacaaatac cactattaca attgaacttg tattaatact
     4621 catcctggtt ttctctccaa gtgaactcaa cgcttcatta tactctatag atttaaaact
     4681 aaaaaataca aatacactaa atacaattga aataaagtac attaaataat taaaaaaact
     4741 attctttaca ttttgcattg caattctaaa taaagtcatt tttattaact cctccaatta
     4801 aggaaactgt atttactatt ttattataga actctctgtt actttctccc tttacaattt
     4861 ctgtgaatat tattccatcc tttataaaga gtattctatt gcaaaaactc gcacttatag
     4921 catcatgagt taccatcaat attgttttat tgctgtcttt gtttaatttt aatagacaat
     4981 tcaacaaatc cctagcagat ttagaatcta atgctcctgt aggctcatct gcaagtacta
     5041 atgatggttt tgttgctata gctctacata cagctcctct ttgcttttgt ccaccagaaa
     5101 cttcgccagg gtatttatct aatatagatt ctatatttaa ttcttttgaa atctctttta
     5161 ttctattttc tattactgat actctttcat tttttaaaga aagaggcaac attatatttt
     5221 cttttattgt aagtgtatcc aaaagattag aatcttgaaa tacaaagcct agattatcac
     5281 gtctaaaatc tgccaattca ttttgcttca ttttaatagt attctttcca tttatataaa
     5341 tatctcctga tgaaggtaaa tctattgtag aaataatatt taaaagtgtt gatttaccag
     5401 caccggaaga ccccataata ccaacaaatt ctcctttata aaccttgaaa gttattcctc
     5461 ttagagcttc atgttttgaa ccttttcttc catactcctt ttttatattt tcaacagata
     5521 atatttcttc catagttaat aatcaccttt catcacaatt agttatttat caattctcac
     5581 aaatatatta tatatattaa aatggctttt aaacatttaa ttatattaat ttaaggttac
     5641 attttcgtaa gtattaatta tatttcttca aatttattgc aattatgttt aaaatataat
     5701 ttatcaagta aaatatagtt atattaatat aattatttta ggtaataagg tagaaatatt
     5761 ttaatttatc aagtagaata tagttatgtt aatataacta ttttgaatta ggaggtaaga
     5821 atgtttaaaa taatggtagt tgaagatgat gtctcattga aaaatatcat agcaaagtgt
     5881 cttactaaat ggggacatga tgttcatcaa atagaaaatc ttgaaaatat aatagaagag
     5941 ttcaaaaact ataacccaga attagtttta ttggacataa accttccatt ttatgatggt
     6001 tttcattggt gtaatgaaat aagaaaaatt tcaaaagttc ctataatttt tatttcttca
     6061 agaaattcta atatggatgt aataatgggt gtaaatttag gtgcagatga ttatatacaa
     6121 aaaccttttt ctgtagatgt cttagtagct aaagttaatg cccttttaag aagaacttat
     6181 aattttgttg ataataactc aaatcagatt attcacaatg gtgttacttt agatttatca
     6241 actgcaacaa taaactatga agataatact attgagctaa caaaaaatga aatcaaaatt
     6301 ctccatgagc ttatgaaata taaggggcag atagtaagta ggaataaact catgaaaaaa
     6361 ttatgggata atgattggtt tgtagatgat aatacattaa ctgtcaatgt aaatagaata
     6421 cgctcaaaat taaatgaaat tggtttagaa gattttatag aaacaaaaag aggattgggt
     6481 tatataatca gttaaaacaa ttctaagtag gtgaatttat gagctttaaa gattttctca
     6541 aggataaact aggtttttta gtatacaatt ttactttctt aatttttaca gtatcagtta
     6601 ttatattttc tcctgtagat gtttttctga ctgatactat tttatatata ttagttgtaa
     6661 atgttgtgtt tttattttta tatctattta ttagctacat caagaagaac aaatttttag
     6721 ataagataaa aaatgataca ttcaaaatta atatgaatga tatagaatta gctagatgta
     6781 aaaatgaaga aaaaatatac ttgaacatta ttaaaaatca tcaatatcaa tgtaataaca
     6841 taataaataa taatatcgag aaatttgaag aaaacaaaga gattttaaat atgtgggtac
     6901 atgatgtaaa gatacctata gctataataa aactcattct tgaacaaaat gaaaatttaa
     6961 ttgatgaaaa aatttcagat gacatagata gtgaaatatt tagaattgaa aactccgttg
     7021 aaaaaatttt atatttatca agactcgaag attttcataa ggatttttta attcaagagg
     7081 taaatattga aaaaatcatt agaaatatta taaaaaaata ctcaaaatat tttatttcaa
     7141 aaaaaattat tttagactta aataatttga attttaaggt tttatctgat gaaaaatggc
     7201 tatacttcat attcgagcaa ttattgagta attccctaaa atactcctca ttaggagata
     7261 atatatctat ctattgcaaa agaaccaaaa attatttaca attaagagtg gaagatactg
     7321 gttgtggtat aaaaaaggaa gatttaaatc gaatattcaa taagggattt acaggtaata
     7381 atggaagaaa caattctaaa tctacaggtc ttgggcttta tttagtaaaa gaactttgtg
     7441 ataagcttgg tcataaaatt gatgtagatt cagagtacaa ccaatataca aaatttacta
     7501 ttacattcaa atgtgattta tagtatctta ttattgatag tttattttca ttaacttata
     7561 ttcaacttct tatagtaatt ctatatgtac atcccagtat ataattaagt agtttttata
     7621 aaaaggagga agacatgtct tttctaaaaa aatttaaaaa taaaagattt agaaataaca
     7681 gttttaaaag taacaacttt agaaatagca gttttggaag tagtggcttc aagtctaaaa
     7741 ataaaggttt taaaaacaat ccctttaaaa ataagagatt caaaatatat gcaggaatag
     7801 cagtaatcat acttttaatt ctaggagttc ttgcttatgt tgattcgaaa aacactgaat
     7861 tacaagctaa tgaaaatttt atcgaaacat atactattcc tgaaaatgaa aaaatattta
     7921 taaatgggat ggttgttcct aagcaaacta aggacttcaa tatatctgga gattatgagt
     7981 taagtgatgt taatgttaca aatggtcaaa aagtaaatca aggagacctt ctttttactg
     8041 ctaaaaatcc aactataata gcagaaatag atagtttaaa atcacaactt agtcaataca
     8101 aaaaacaaaa aatatcactt tctgatattg ctgaaaataa agatgctatt gcttctataa
     8161 atgcacagat aactgcttta aactctcaga tagcttctct ggataaaaaa gcttatgaca
     8221 gagttactgc tccttttgat ggcacagtat acttgaatga ccaaactgga aatccagacc
     8281 aaccagtttc atttatgact attcaaggtc tagagtttta tatgaaagga caagcaagtg
     8341 aacaagattt acctaaaatg aagattgacc aaatggtcaa tatactagtt ttttcaactg
     8401 accaaaagct tactggtaga ataagtttta tatctgataa accatctact ccaaatactg
     8461 aaatgggagc tcagcagaat acactatctt attatgatat aaacatagca tttgataatc
     8521 aagaaggatt agtaaatgga ttccatcttc aagcatcact tgaagtagct aattcaagct
     8581 ttaaaatacc agcatcttgt gtacttaaag acaacaaaca ctcatatgta tttaaggatt
     8641 tagatggtat attgaaaaag caaattgtag atgtagcaag tcaaaatgat gattttgctg
     8701 tagttagagg cggtcttgaa caaggcgata taataataaa acaccctact aaagaaatga
     8761 aagaaggaga cccagttcaa ggcgatggcg taactgctgg ttctaataat ggagatacta
     8821 ctccaaacaa aaaagtagaa gaagttacta tggatgtgaa ttaatttaca tatgttaatt
     8881 aaattagaaa atattcaaaa atattacaaa gtagggaaag atgaattaca tgttttaaaa
     8941 tccttaaatt tagaaattga atctggagaa tttgtcatga taatgggtaa gtctggtagt
     9001 ggtaaaacta ctttacttaa tatcttaggt tttctagatg tatttgatga aggaagatat
     9061 atatttgatg gaacagatgt aactaatttg agtgaaaatg aacgttctgt ttttagaaat
     9121 attaatattg gatttgtttt ccaacaattt aatttaatag aaactctaaa tgtatatcaa
     9181 aatgtagagt tgcctctaat ttacaataaa gcactaaaaa aatctaatag agaagaaatt
     9241 gttaaagata aattaagttc tgttgggctt ttggacaagc ttaagcagaa accacttcaa
     9301 ttatctggtg gtcaacaaca gcgtgtagcc attgcacgtt gcctagcaaa tgaccctcag
     9361 ataatctttg ctgatgaacc gactggggca ttagatagtg aaactagcag agaaattatg
     9421 gagcttttaa caaggctcaa caaacaaggt aagactataa taatggttac acatgatcaa
     9481 gatttaacta agtatgcaac taaggttata cgacttaaag atggtgtgtt tacttcggag
     9541 gtgtaatcat gagtttatta aaaaattctt tggccaattt aaaaggtcac aagcttcgtg
     9601 tatttgtagc tttactctgg attataatag gaataacttc agtaatactt gttagttcta
     9661 taggtaatgg atttcaaaaa gaaattaaga aatctgtaaa caatgtaaac cctaataaaa
     9721 ctactatttc gtttgaatca gccgataaca caggtcttac tgatgatatg agtatttttt
     9781 taaaaccctt taatgcaaaa gatttagaag aattatcatt tgttgaagga gtagaaagaa
     9841 tagctccttc aagagatggg tttaaccttg attcagttta ctcttcacaa gcatcttttg
     9901 ataaaaaaac tacgtatgtt gatgttggac cagtaaaaaa agattctaaa ataaatttaa
     9961 tttgtggtag agatttttct ttagatgatg aaaaaagaaa agtaatttta cttacattac
    10021 aaagtacaag tgaaattttt gaaaatccag aagatgcctt aggtcatggt atcaacataa
    10081 atggaactat atttgaaata ataggggtat tagatgattc tcagcaaaac caagctggag
    10141 gattctttgg aggttaccaa gatatgcaat ttactacttc cctagtacct aaaaaggctt
    10201 ttgacacttt aatgagtcaa aattcttatt caaatgaaat ttaccagtta gacttagttt
    10261 cttctaaagg ctataatgta aatgaagttg caaacaatgt tatagctaaa ttatatgaga
    10321 tgcaccctgg tatcaatggt tcttatacta caccagaccc aactgaacag acagcttatc
    10381 ttgaaagcat taattccaat gtaaacaaat atgtatctat aataactgta gttgcaatgt
    10441 ttgttggtgg tattggtgta atgaatataa tgtatgtatc tgttatggaa agacaaagag
    10501 aaattggtat aagacgtgct attggagcaa aacctaggtc tatattattt caatttttag
    10561 ttgaagctgt ttttataaca gtatgtggtg gaattttagg aactatagtt ggatttgctg
    10621 ctactaacta tgtttctaaa tatataggtt ttgaagctat acctagctta aatagcttat
    10681 tttatgcaat tgtagctact atattgactg gagttgtatt tggtctgatt ccagccttta
    10741 aagcctctaa actagaccct ataaaggcaa tttataagta gaaattgtat aaagattttc
    10801 gatttttaga ttagtttata taaaacatac ttaaatatat aacgcactat tatatatgat
    10861 agattaggaa cttaatcttt ccaaatataa tagtgcgttc tttcataaaa aggattctct
    10921 tccttactat atctaaatta ccaagatgtt atgttctaat tgttcaaact aatacttcca
    10981 attttgatta atcaatctca ttctcctaat atacaatctt ttactttcaa tcattgtaca
    11041 ctccgcctta aaaaaataat cttaaattat gcgttatata caatctcccc attacatatt
    11101 gtataattaa cctttccata taaagattta cctttaaatg gtgaattatc agctttagaa
    11161 acaaagcttt caactgtcca ttcttcttct ggattgaata taacaatgtc tgctacagcc
    11221 ccttcttcta taaatccaat atttaaattg tacaactttg caggatttat agacattttt
    11281 tctattaact gcatcatact aagatgattt ttatgcacca aatttgttat tccaagagct
    11341 aaagaagttt caagcccaat aattccactt ggagctttta taaactctct atctttttct
    11401 tctttactat gaggtgcatg gtccgttgct attatttcaa tagtaccatc atttaatccc
    11461 tctataatct tatctctgtc ccatttactt cttagaggtg gattcatttt tgcatttgtt
    11521 ccaaactcca atacatcttc ctcagtcaat gtaaagtgat gtggtgaagc ttctgcaact
    11581 acatttgcac ctaagtattt tgcaaatcta accatatcaa cagatacacc tgaacttata
    11641 tgttgtatat caactttagc accagtcttt agtgccaaca tacaatctct ggctaccata
    11701 acatcttctg ctacacttga tgcacctttt aatcctagtt ctgaagctac ctttcctgca
    11761 tttacacctg gatttccaac taaagaaggg tcttcttcat gaaaactaag tggtacatcc
    11821 aactcttttg ccttaatcat tgcctccata attagattgc tatccattaa aggtaatcca
    11881 tcatcagtaa accctggtac accagctttt ttaagagctt ccatatcaac taactcttta
    11941 ccttcaaaac ctttagttat agctgctgct tgtaaaacat ttatacatgc attttttgac
    12001 ttttctttaa cataattaaa agtatcttca ttatctacaa taggattagt atttgccata
    12061 catataacag ttgtaaatcc acctctagca gcagatttag ctccactttc tatatcttct
    12121 ttatatgtaa acccagggtc tctaaagtgt acatgtacat ccactaaacc tggagcaact
    12181 acattaccac tagcatctat tattttttca tattcatcac tttcatcaaa cttgcctatt
    12241 ttataaattt tattttcttt tataattaag tcaatattct catctctttg acttttaggg
    12301 tctattactc taccattttt aattaaaatc atattatttc tcctttatat ttttaattta
    12361 tatagactca tataatatta tacattattt tacatactta aatacaaaat tacgtttgac
    12421 atcaatagcc tttttaggac aaagttcatg gcaacagtaa catcttatac atttacttaa
    12481 gtctataata gcacccttag tccctatctc tatagtggat gcaggacaag cttccttgca
    12541 ttttccacat tttatgcaat cttgaaatct taccacaggc tttggtgtta taagctttga
    12601 aataggttca tttaaaaatt ttggtagctt tacagaaaac aatcttaaat ccttacttac
    12661 atttggaatc ttgtaatttt ttataattaa atcttttata tcttcaccta aaatttcaat
    12721 atctgaaaaa tcttcttgta tatatcctct cttaatagca cctctaattg tagcaactct
    12781 atttggaagt aaacttataa tcttacatgc aacaacatct atagcatatg gattttgtga
    12841 tgctaataaa actcctattt ctcgagtagt accagctgaa ggtccatcac cttccatacc
    12901 tactatacca tccataattg tcaatgttgg ttttatataa tcacaaatat ctaaaagtac
    12961 attttcgcaa aacaactctt ctgtaggaaa tctataatgt atctctgctt ttttcaatcc
    13021 agctatgcat ccatataagt tttttgtacc accagtaaaa gttgccatta tatgagtctt
    13081 taatttacaa agatttatta tataatctga atctactatt ggtttaataa tatccatata
    13141 ttttagaaca tgtgcttttt cactatgtat cttaacatct gaaacatcat aatttaactt
    13201 aatgcccagt tcatttgcta cttcttcaat tccagatgcc ttataaatgc tcttaagaga
    13261 actttgatta tatggaccac cagggctatc tgctattgta atatcacaat ttaactctaa
    13321 aagtttttca catacaactt ttacaaccat aggatgtgta gttgtagctt cttcaggctt
    13381 ttttttcatt aataaatttg gttttataag tactttgctt ccttttttaa caaacttatc
    13441 tataccacca atatcctcta aatttttttc aatagataac tttacttctt cataattgta
    13501 agttttacaa ctcctaacag ataccgactt catattatct ccatccttct atcacaacag
    13561 tttatttgta taatttaaaa aaggagaaac caaagtttct ccttttaatc tatgttttaa
    13621 ttgttttaat tattattttc caaaatgtct gtttaataat cctaagaatg ctttaccatg
    13681 tctagcttcg tctttacaca tttcatgtac tgtatcatgt atagcatcta atcctaattc
    13741 tttagctctc ttagctaatt ttaattttcc atcagttgca ccatactcag catcaactct
    13801 aactcttaag ttttcttttg tatctgcaac tacaacttct ccaagaagtt ctgcaaattt
    13861 agcagcatgt tcagcctctt caaaagctat tctcttatac gcttcagcta cttctggata
    13921 accttctcta tcagcttgtc tactcattgc taaatacatt cctacttctg tacactcacc
    13981 agtaaagtta gctcttaatc cttcgattat ttctgcatct acaccttgag ctactcctat
    14041 tctatgttca tcagcccaaa ccatttcgcc tttcatttct tcaaatttat cagctccaac
    14101 tttacatact ggacattgtg ctggtgcagc atctccttca tgtatatatc cacatactgt
    14161 acaaacaaat tttttcataa ttaatttcct cccaatttta tataattaaa tttttatttt
    14221 taagtttaat aacttgctac aagaatatat ataccccaga ctttatagct taaacactaa
    14281 aaataaaatt tatttcctaa ttaattttat cactttgaaa caccagtatc aaccaagttt
    14341 tgatgtcaaa tttctacata atacataatt tatttgatta attaggaaat agttgtcata
    14401 ttaaatactt tctaatgaag actcctctga atctttaagt ttcacttttt tgctctttaa
    14461 aaaagataat ttagtttctg cagttatgat tgcaacaaat atcaagatac taccaataac
    14521 caattttgct gtaataagtt cctttagaat tattatagaa aatattgtac caaatacagc
    14581 ctctgtggat aatattatag ctgttctagt tccatcaact cttttttgac atatagtctg
    14641 aaataaaaat ccaattgtag tactaaatac agctagatac atagttccca tgtaaccaga
    14701 taattcagct tccatcttta attgacctgc aaatgtttga actacaacag acattaaaaa
    14761 cgctactgta aattgaatag ctgtcaatgc cattgggttg ttatcttttg caaactcact
    14821 tgtaaagaat atatgaaatg caaatccgaa tgaacatata agtgttagaa aatctccaaa
    14881 attaatagag aaatcagctt ctaaagaaag tatcccaatt cctataagag ctaccaaact
    14941 acttattatt cctattttat caagttttct tctataaagt ataaatccta tgaatggaac
    15001 tattacaaca ttagctgctg ttataaacgc atttttagat ggtgtagtgt acataagtcc
    15061 aatagtttgt actgtgaatg ctagaaataa aaatattcct aaaatccctc ctgcttttaa
    15121 taatttttta cccatattgg cacgaatctg tttaaaaaac agtaaattca taattatagc
    15181 tgccaagaaa aatcttaaag ttatgatttg tagaggtgta agcccaccgt ctaatgcaaa
    15241 ttgggttgct acaaagccac ttccccatat aattgctata aatattagtc ctatttctcc
    15301 aaagtatttt ttcaataaag ccccctcctt tttatttttt tgcaaaatta taaaccccct
    15361 aaacagcaag agagtttttc tataagcatt actataaatt aatatagtaa attttttcag
    15421 tattttaaat ctaaatttac atacattttg agctcaaatt tatatccact atttaacagt
    15481 aatatattaa tcattttttg taaacacctt tttaataaat ttttatattt tttatatttt
    15541 tttacctata ctaaattttt ttatagatat ttttaatata tatgatactt taatattatg
    15601 caaataatgt catataagtt acactttagt tatcttagtt acaactttgt cggtttactt
    15661 tttctacttt cttcgatata attataatat atttttgata caattcgaca aaagggggaa
    15721 tgctgtaatt atggtaaaaa aaagaaaaaa gaaaactgtt gcacttacta tacttgttgt
    15781 aatagttatt ggtatttttt ctatggcatg ggcggacatg tctagaaaaa aagaaatgaa
    15841 agaaactcaa gaaagactta aagctgaaag attagaaaaa gaaagaattg aaaaagaaaa
    15901 aaatgaacct attattggtg caaaaaaaga agctgtaaaa gaatatggat atgacgcaaa
    15961 aatagtttgg gacaaactta acaaatacga ctattcaaac aatggagaaa agatagtctt
    16021 tcttacattt gatgatggac catctactac taatactcca caagttctag atatcttgaa
    16081 aagacatggt gttagaggaa ctttctttat taagggtgat tctcttgaaa gaaaaggagc
    16141 taatgaaatt ttaaaaagaa catttgacga aggaaatgca atagcccatc actcttatac
    16201 tcatgactat aaaaaactat atcctaacag aagcctaaat ctcgatacat tcgtaaatga
    16261 acttaacaaa actgatgaag ctatgaaaaa agtcttagga aagaattttt cctcaaatgt
    16321 agttagatgc ccaggcgggt atatgtcatg gaaaaatatg gaacctctag gaaactactt
    16381 aaaagagaaa aacatggcat caattgattg gaacgcttta aatgctgatg cagaaggtaa
    16441 aaagaaaaat gcacaagaat tatttgaaca tgcaaagaaa tcttctgaag gcaaagaaat
    16501 ggttgttctt ttaatgcatg atacttatgg aaaacaagaa acagtaaatg cattggacca
    16561 aattataaca tattttaaag acaatggtta tcaatttaaa attttaatat aataaaaaag
    16621 caagtttatt gaatgtacat tttatactca atagacttgc ttttacttta ctctatttta
    16681 ctagctcgat ttttacaaat tttttctttc ctatttgaac aactaattca ctctctttta
    16741 caatagtgct taaatcctct actttttcac catttacctt tactccacct tgagaagcta
    16801 atcttctaac ttcactctta ctcttaacaa tctcattaga aactagtact tcgattaagt
    16861 caaatccatc ttccttaact tgaattgttt gtatatcttc aggtatttga cctttttgga
    16921 atacagattt aaatctttct tcagcttctt tagcagattc ttctccatgg tataatgtta
    16981 ctatttctct tgctaagtcc atctttatat ctcttggatt tactgaaccc tctttcaact
    17041 gagattctat tttattaact tcatcaggat gaacatctgt cactaaattg tagtatttaa
    17101 ttataagttc atcaggaatt tccatagatt tttggtacat tattcccgct tcttcatcta
    17161 ttccaatata gttacctaaa ctcttactca ttttttcttt accatctaat ccttctatta
    17221 aaggcatcat tattactatt tgagactcca taccaaattc tctttgtaat gatcttccca
    17281 ttagtaaatt gaatctttgg tcagttccac caagttctat atcagcttct aatgctatag
    17341 agtcatatgc ttgcattaat gggtagaaga actcatgtac tgatattggc atttgtcctt
    17401 catatctctt tttaaaatct tctctttcta acattctcgc aacagtaata gttgctgcta
    17461 attttattac atcttcaaaa tttaacttag ctaaccactc gctattaaat cttacaatag
    17521 ttttttcttt atctaaaact ttgaaaattt gttcttcata agtttttgca tttgcaagaa
    17581 cttgctctgt tgttaaagct tttctagctt tagattttcc agttgggtct ccaatttttc
    17641 ctgtaaaatc tccaattatt attactattt gatgacctaa atcttgtaat tgtttcatct
    17701 ttctaagaac tactgtatgc cctaaatgta tatctggagc acttgggtct agacccaatt
    17761 ttactatcat aggttttcct tctttttctg atttaataag cttttccctt aactctttct
    17821 catctattaa atcatctaca cctttcataa ttattcgcat ttgctcgtct atcgatttca
    17881 tttttcattc ctcctaaaat atttatataa tctataattt ttatttttat aataaaaaaa
    17941 gctttcatcc tcttaaaagg acgaaagcat tgcttacgtg ttaccacctt agttcatcaa
    18001 tatctcacga tattaatctc ttagagtaca attacatata ctcgtgtact ataacgtgta
    18061 ctaatccgat atctcttaat ggttgttatc tttcagagat agtgctctga gatgtattca
    18121 aactaaatca atttattcca tttcaccaaa ctggaactct ctgttaaata aaatctagcc
    18181 ctacttcttc tcttcatagc atttatatat tcagattatt tcatcaatta caagaaattt
    18241 ttcttaactt actcataata tattattatt tttatatttt gtcaaccttt tttattatta
    18301 tatacatgtt tttttacatt atactacttt tttatatttt ttaccaatac ccaaaattta
    18361 tttttcaatc aaaagattta tttgtttatt gactatatta ctctgactca atcttatatt
    18421 tattttctta tttaaaaatg cgtttataat tattaaacca ataactgtta catcaaatat
    18481 aaaaaacagc aataaaatta ttatcaaaaa taaaattcta gcatataata attttctaaa
    18541 cttagctatt ataaagtttt gtagtgacat acatgagtct ctaatgataa aatagacact
    18601 tatataggtt attgatataa agattgtttt taaataaaca gaatcaactt taacattcaa
    18661 cagttttaga acttcaaaaa tggctagata agaaacacat atgtaaaaag ctttttttga
    18721 gcaacataaa aattggttta aatttctaaa attcttaaat attaaaaatt tttttaaaga
    18781 attagaatct aaaatatgca atttattccc taaaattaaa cttaataaat atatgcaaaa
    18841 caccatacca aaaggaaaca atgctatcat taaataataa ataaaatttg tatacccatt
    18901 aaaataaatc catttgctat atccttgaaa ttctttcata aaactataac ctattaatgt
    18961 tgaagcatat atatcaatga aaaccattac aataacccca aatactgaac catatactaa
    19021 atcatccata accattgtag gcttatttat tagatagcca cacattatac caagtaatac
    19081 actctgactt gcccaaatag cagttcctaa atttccaagt accagagaaa ttattaaaag
    19141 cgaagtaatt ccagataaaa tggtatactt taaatcacat ttcaagcaga ttatacaaaa
    19201 aaatactggc actataaaat ctaagtaaat agcatatcca aatccagtac tcacagctat
    19261 aattgttact actatgaata aagatgacaa taaagctgct tcagttaatt ttttagtagt
    19321 attcaaaaca ctgcctccat aaatcataaa ttttctaact aaagttttgt ttttaatata
    19381 gtatatcact ttttaaaaat atttttaata aatataaatt ttaataaagg tatttatgtt
    19441 aaaaatggta taatgtatct taatattcag ttttttaaga tgctaggagg taattactat
    19501 gtttaaaatt aaacacttta atgatttgag tttagatgaa ttttatgaaa tagcaaaatc
    19561 aagatatgag gtatttgctt gtgaacagaa gatattttca ttaaacgatt atgatgatat
    19621 agataaaagc tcttatcaca tatttttaaa agaaaatgga ttgatttgtg cttacgctag
    19681 aataattcct aaagaataca gctcttataa tgatgtttcc attggtagag ttttagttct
    19741 ttctagtcat agaagaaaag gattagcaaa acaaatgatg gattgtgcta tagattttat
    19801 aaaagttaac ttacacgaaa ataatataac cttatcagca caaacttata taaagaacct
    19861 ttacttatct tgtggtttta aagaaatctc agaagtatac gacgaagcag gtattgaaca
    19921 tattaaaatg agattatagt gttgacaagc taatattgtt aatatataat ttaagtataa
    19981 attaaatatt gaattgatat ttaggtattt gaaaatacct tacatagagt cagaaggctt
    20041 ttgctttctg acttttttat tatcaaaatt caataattat atggattcaa agtgttaatt
    20101 tttattctat attctacttt ccccaaaagt aagaattata cccaactttg tatgataggc
    20161 atcttgccta tctttttttt gtaaaagtaa caaggtaata atataatgca tagtttaaaa
    20221 taagaagatt agcccaggct aaatttcaag catggaggtg ctattatgaa aaaccttaac
    20281 gatattcaag tgaaaaaaac tgtcaaagtt gaagatatat tatctagtgg taatttaaga
    20341 gaaagaatgt tagcgcttgg tcttactaga ggagctgtta tagatgtagt tagaaaaggt
    20401 ccaaaaaata atttaactgt ctataaaatc agaggtagca agatagctct acgacaagaa
    20461 gaaagtagct taatattagt ttctgacatt taaaaatttc tagcaggagg atattaatat
    20521 ggggttgaca cataactcaa ctaaaatgag ttctttaaaa gacatgtttg atatagacaa
    20581 taaggaagac cagtttgtaa ttgcattggc tggcaatcca aatacaggta aaagtactgt
    20641 atttaatcat cttacagggc ttagacagca tactggaaac tggccaggaa aaactgtagc
    20701 tacagctcgt ggtaatttta aatataaaaa taccgaatat gcattaatag atttaccagg
    20761 aacatattct ttatttgcct tatcacaaga agaaattgta gctcgtgatt ttatatgttt
    20821 tggtaatcca gatgcagtaa tagtagtatg tgatgctaca tgtcttgaaa gaaatttaaa
    20881 tttagtattt caagtgatgg aacttacaga taaagttatt ttgtgtatta atttaataga
    20941 tgaagctaga aaaaaaggca ttactattga taaaaaactt ttagaggatt ctcttggtat
    21001 tccagttatt ttaactgctg caagaaatgg ctctggtatg gatgaactat tggatacttt
    21061 aaatgatgta tcttttgaca aatataaatt aaataataaa cctgttagat acaatgaaaa
    21121 tatagagaat gtggtaaaat caattcaacc agaattggat aatattatac caggtataaa
    21181 ttctagatgg ttgggactta gacttattga tggcgatgaa agtatatttg aatctatgag
    21241 taattatata gacaaagatt ctatagatgc tattaatgaa gtaaagaaaa agattccaga
    21301 caatataaat aaacagaaaa taagagatga gtttactaaa atcaactatg attatgctaa
    21361 aaaactgagt gatgagtgtt gttctaatgt tgctaaaaaa tcaactgata gagaagaaaa
    21421 agtagataaa atattaacat ctaaaatatt tgggcttcca ataatgctct tattattagg
    21481 tactatattg tggattacta tagaaggagc taactatcca tccactttat tatctaattt
    21541 attactcgga tttgagccaa gtatttcggg tatattaaat agtattaatt gtccatcatg
    21601 gttaaatgat atgttggttt taggattata cagaacatta gcatgggtaa tctctgtaat
    21661 gctacctcct atggcaatat tttttccatt atttacccta cttgaggatt ttggatattt
    21721 gccaagagtt gcatttaact tagaccacct atttaaaaaa gcttgtgcac atggaaaaca
    21781 gtgtttgact atgtgtatgg gatttggatg taatgcagct ggagttattg gttgtaggat
    21841 aattgactct ccaagggaaa gacttatagc tatacttaca aacaactttg ttccttgtaa
    21901 tggtcgtttt cctactttga tagctatatc tacaatattt tttagctcag ttataaccaa
    21961 ctctttcgta tcaagtgtag caactgcact ttgcataact ttactgataa ttctaggtgt
    22021 tataataaca ttgttggttt cttatactct ttctaaaacg ctattaaaag gagttccgtc
    22081 tacatttaca ttagaacttc ctccttatag agttcctcaa ataggaagaa ctttatatac
    22141 ctctataata gatagaacaa tatttgtttt aggaagggct gtaatggtag ccatacctgc
    22201 tggtgtcata acttggatat ttgcaaatat atatatagga gatttaagta tattatcaca
    22261 tgttgcaaac tttttagacc ctttagctaa attaattggt cttgatggtt ttatattact
    22321 tgcttttatt cttggattcc cagcaaatga gatagttgta cctatacttt taatggctta
    22381 cctagcaact ggttctatga tagaattaga tagctttagt gctttaggtc aagttcttag
    22441 agaacatgga tggacttatt tgacagcttt aaatgttatg ctgttcagtt tactgcattg
    22501 gccttgtgca acaacacttt taacaataaa aaaagaaact ggtagtttaa aatggactgc
    22561 cttaggattc ttaatgccta ctatacttgc ttttgttgtt tgttttttaa caactacagt
    22621 ttacaattta tttatataat tagtattaac tgacagtaga catatattag agaaactatt
    22681 taaaaattta tatactttat tataaagcat agagatatat tcaatgataa gtaaaattac
    22741 ttaacatttg aatatatctc tattttaatt cttatctgga tacttggatt gaaatttcag
    22801 tcatataatt atcttcatta ctttcacaaa aaaagtcaag tatactctcc tcatacgaat
    22861 ttccaacaat tttatattca ttttcatata tatatttttt caatttttcg taagatttat
    22921 atgaatcctc atattttcca atatgtttta tgcaagcata cattccttct ggctttacat
    22981 atagcttttt atcctttatt tttttatcta tcttcaaata aaaacttgat atacttaaat
    23041 agtccccatt ttttatattt tcattactta ctattactcc caactcatat ccttgataca
    23101 aatttttaga tttacaataa ttggtgaaat ctattaattc catcataaaa tcactattac
    23161 tcatattact caaatcgctt gatagaacta aatattcttc aaactttttg gatatataaa
    23221 tttcttcact attcatttta gaaattcctt caactgttat atttattcta ttttgcatct
    23281 tagaacttat ctttcttagt ttttttattt tttctcttat ctttttttct tcttctttaa
    23341 gcattttcac acaaagctgg ggagttctat tttgtatata ctcttttatt tcctctaaac
    23401 tcattcctat ttctctcaat gattgtaata tatcaagtgt atcatattga taaactgagt
    23461 aatatctata attattttta tctttatatt caggagaaaa aatacctatt ttgtcataga
    23521 aaatcaatgt ctgcttagat ataccacaca atttagcaaa ttcacctgtt gtaaaatact
    23581 gtttttccaa gggttataca ctccttttct ttttgttgtc tatatagtta ctatattctt
    23641 tattatttac taaatcaagt agttattatt ttagaaaatc aatatgattt tgattttaaa
    23701 gcttaaatat cagttagatg tcagttataa atattttatc cattcccatc ataaaaaaga
    23761 tatcccctct taacttttgg atggaatatt atatttatac ttgttagagt gaaaattgta
    23821 ataggtgcta caataagata tttaattaaa cataaagtta attattgtaa taaaaaatct
    23881 ttagataaat tagagttaaa gtatggaaat atagatagag aaaaagctgt taaactagaa
    23941 atattttatt aatatttaat agaacttgaa tatatagaaa tgagtttatt aataagaaga
    24001 ttagatactg caataacatc attagcatta gtatctatta taacaatagc atcatattat
    24061 ttaatcagaa aaaatgtgta attatgtaag ctatttataa taaaacactg ataaaattaa
    24121 taataaaaag gtaataggat ttctatacta ccttttggtt tttataatat agtgta
//
LOCUS       DAMKNB010000053        24175 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.055, whole genome shotgun sequence.
ACCESSION   DAMKNB010000053 DAMKNB010000000
VERSION     DAMKNB010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 24175)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24175)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24175
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.055"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            complement(313..1029)
                     /gene="dapD"
                     /locus_tag="PC494_002397"
     CDS             complement(313..1029)
                     /gene="dapD"
                     /locus_tag="PC494_002397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HDF3912892.1"
                     /translation="MVNLNDAYEIARYIKEVKKKTPVKVYVNTNSLHFQSTDKFKVFG
                     SNGSYIFVGDYEDIMEVLDKHGNDITDTHVEYDRRNSAIPLKNTLSEHARIEPGAIIR
                     DMVTIEKNAVVMMGAVINIGAVIGEGSMVDMNAVIGARGTLGKNVHLGAGAVVAGVLE
                     PPSATPVIVEDDVLIGANAVILEGVRIGKGAVVAAGAVVTTDVEAGAVVAGSPAKVIK
                     MKDEKTADKTKLMEDLRNLD"
     gene            complement(1289..2038)
                     /locus_tag="PC494_002398"
     CDS             complement(1289..2038)
                     /locus_tag="PC494_002398"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HDF3912893.1"
                     /translation="MLKVIATGYDGKMGKILADTIREDNELELVCVAARGLDSYEGDL
                     KIYEDMSTIVEEADVVIDFSHHSNLDNILSYVLKTKTPLVIATTGYNDDEMNKIREAA
                     KVIPVFQSYNMSLGVNVLVKLVKDAAKLLEGFDIEIIEKHHNRKVDAPSGTAVMIANA
                     IKEVLPNVENNYGRYGRSAKRQPNEVGIHAIRGGNIVGEHDALFAGDNEVLTISHQAQ
                     SRGIFASGSIAAAKYLVKQKPGFYNMDSMLG"
     gene            complement(2105..2992)
                     /locus_tag="PC494_002399"
     CDS             complement(2105..2992)
                     /locus_tag="PC494_002399"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HDF3912894.1"
                     /translation="MIFKGSAVALVTPFTKDNKVDFDKLGELVEYQIANGTDAIVSCG
                     TTGEANTMTDEEQLATIKYVVEKVNKRVPVIAGSGSNDTMHSVNLSQEAEKLGVDALL
                     IITPYYNKANKAGLKRHFETIANSVKLPIILYNVPGRTCVNISPSLIVELAKIDNIVA
                     VKEASGDLGQVAEIASLVPDDFAIYSGNDDTILPLLSLGGQGVISVLANVCPQETHDL
                     VAKFFEGDIEGSRKLQLGMDALIAALFIEVNPIPVKTAMNLLGFNVGDLRLPLAEMDP
                     ANLEVLKKELVNFGLKVNA"
     gene            complement(3109..4110)
                     /locus_tag="PC494_002400"
     CDS             complement(3109..4110)
                     /locus_tag="PC494_002400"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HDF3912895.1"
                     /translation="MKKVNVAIVGATGMVGRTFLKVLEERNFPIENLFLFSSSKSAGS
                     KVMFCGKEYIVEELKETSFTGRGIQIALFSAGGSISEKYAPIAASNGILVVDNSSQWR
                     MNPDVPLVVPEVNPEAIKNHKGIIANPNCSTIQAMVPLKALDDKYKIKRVVYSTYQAV
                     SGSGVKGVEDLEKGMNGNPTGFYPHQISYNCLPHIDSFTENGYTKEEMKMVNETMKIL
                     DNYDLKITATTVRVPVKNGHSESINVEFNNPFELDDLVKTLEEAPGVVVVDNPAKNEY
                     PTAVEFDDRDEVFVGRIRRDFSVDNGVNLWVVADNIRKGAATNAIQIAEMALSYDLV"
     gene            complement(4535..5416)
                     /locus_tag="PC494_002401"
     CDS             complement(4535..5416)
                     /locus_tag="PC494_002401"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HDF3912896.1"
                     /translation="MLFKGSAVALVTPFTEDNNVNFEKLGELIEYHIENGTDALVVCG
                     TTGEATTMSESEIFAVIKYTVEKVNKRIPVIAGTGSNNTMLSVHMSQEAEKLGVDGLL
                     IITPYYNKTNEKGLKLHFETIANSVKLPIILYNVPGRTKVNIKPSVVAELAKIDNIVA
                     VKEASGDLAQVAEIAKLVPKDFAIYSGNDDTILPLLSLGGSGVISVLANICPKETHDL
                     VTKFFEGDIEGSKKLQLDMDALIAALFIEVNPVPVKTAMNILGFNVGDLRLPLAEMEE
                     TNLNVLKQELTNFGFKF"
     gene            5739..6932
                     /locus_tag="PC494_002402"
     CDS             5739..6932
                     /locus_tag="PC494_002402"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase"
                     /protein_id="HDF3912897.1"
                     /translation="MDTLKELFKIGSGPSSSHTMGPQRAAERFKNENPDAESFRAILY
                     GSLAATGKGHLTDYIIEKTIAPKKVEIVWEEDIIKDFHPNGMKFEALDKDKNVTAEWT
                     VYSVGGGTIAEEGQRNSKSNSIYHLDTMDEIVKWCKENNKTLVDFVLECEPKDIKDYI
                     KTIKDAMRKSIDDGLSTDEIIPGKLLLKRRASTFYNAYKKDKSFSTLVYAYALAASEQ
                     NASGNIIVTAPTCGSAGVIPGIFFAMQDFYNYDDEKIIEALLVAGIIGNIIKTNASIS
                     GAEVGCQGEVGAACSMAAAAVAYLKGGTIDHIEYAAEIALEHHLGMTCDPVYGYVQIP
                     CIERNAMAAQRAYDAANYALLTDGSHSVSLDQVVETMKETGIDMMDKYKETAKGGLAK
                     HFFSC"
     gene            7138..8256
                     /locus_tag="PC494_002403"
     CDS             7138..8256
                     /locus_tag="PC494_002403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyldiaminopimelate deacetylase"
                     /protein_id="HDF3912898.1"
                     /translation="MREASYLQEQLYKHRKSLNPIAEIGRKEYKTSKYIRDYLDKLGI
                     EYEVYLETGIVGVIEGKRPKKDIAFRADIDGLHSEEGVKHLCGHDGHATILLGLIEYL
                     NDNKEDLNDNIVFIFQPAEEGPGGAKALIDEGVLRKYNIDEIYGLHIYPELPEGYVGT
                     REGYFMAQIGDIDIEIVSKSGHGAMPQNGIDGIVIASNFVSSLQTIVSRNISPIDNAV
                     LTIGRIEGGARRNIIAENIKMEGTMRCFSPEVYEKMKLRVRELARGFELAYNCKVNIN
                     IIDDYIAVKNDKDLYQEFVEAIGSDIVVELEPLMISEDFSYYQKEVPGLFFMLGSRNE
                     EKGFVNGLHNINFNFDEKICVNALNVYSKLLKYKEAID"
     gene            8387..8632
                     /locus_tag="PC494_002404"
     CDS             8387..8632
                     /locus_tag="PC494_002404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="small, acid-soluble spore protein, alpha/beta
                     type"
                     /protein_id="HDF3912899.1"
                     /translation="MKEKVQREKKITNGKNTKILTNDDIMKYEIASELGLMDKVGERG
                     WAGLTAKEAGRIGGMLTSRKKRLKKIVEEQNKKDESI"
     gene            8619..9365
                     /locus_tag="PC494_002405"
     CDS             8619..9365
                     /locus_tag="PC494_002405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HDF3912900.1"
                     /translation="MSQYSDFAFVYDELMNEVDYNGWVKYIEDIIDSEGVKVKNILEL
                     ACGTGNLTIPLTKKNYDIAGIDISDEMLSVAREKAEKEGVELVLLQQDISELDFEISD
                     LDCVLCACDGFNYITYDDDLENIFSKTYELLKKDGIFIFDISSFYKLANILGNNMYGE
                     NREDIAYMWQNYFDEEENLIEMELTFFIKDECGKFERFEEIHQQRAYTEDEIVDMLEK
                     SGFKDIKYYGDFTFDKPSEESQRIFFVCKK"
     gene            9648..10523
                     /gene="hslO"
                     /locus_tag="PC494_002406"
     CDS             9648..10523
                     /gene="hslO"
                     /locus_tag="PC494_002406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HDF3912901.1"
                     /translation="MRDYVLRATSGNGQVRAFVATTRNTVEEARRLHETTKVATAALG
                     RTLTATSIMGLMMKNDSDKLTVIIKGGGPIGTIIATSDSKGMVKGYVGNPQVEVEDYP
                     NGKLNVAAAVGTEGVVKVIKDLGLREPYNGTYPLVSGEIAEDFTYYFAVSEQTPSVVA
                     LGVLTKEDEVEFAGGFIVQLMPDAEEETIAKLEENVAKLPSITNMLKEGKSPEDILNI
                     VLDGLEPKILDTCEVGFICECSKERVKTALVAIGKKSLAQIIEEDKKAEVGCQFCNKK
                     YMYSEEELLEILKEM"
     gene            10914..11714
                     /locus_tag="PC494_002407"
     CDS             10914..11714
                     /locus_tag="PC494_002407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIG-L family deacetylase"
                     /protein_id="HDF3912902.1"
                     /translation="MESKTKYIGISILILLMIFLIAKNFNGKLEIPIPESNSRKFKSA
                     AVFYPQHQDDEVLWGGSAIVDAIKQCGVDNVYVVLVSDGSGVNVFKANTKFRNLTRKQ
                     KEELRNNEFKSALRELGVKPQNVIILADIDKKEGTHYELMEKTILDFEHKFKGNVTHI
                     AHHYKYDDHIMHRKNGEVLKKLKREGKIKDDLYFVKPKYVKYIPRNERAIYKAMDFDD
                     YNKVKSACYEYKVVNSKRKMYGIGYISAHSYFEHLLNDPELTSVLSED"
     gene            12241..14481
                     /locus_tag="PC494_002408"
     CDS             12241..14481
                     /locus_tag="PC494_002408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HDF3912903.1"
                     /translation="MNNEFIILKGCKENNLNNISLKIPKRKITIFTGVSGSGKSSIVF
                     ETIAKESQRQLNERFSTFVRSFLPKYGEVKADCIENLSTPIIIDQSRLGGNSRSTLGT
                     ITDVNSFLRALYSRFGSEYIGNANMFSFNNIDGMCPHCHGLGKKLVPNMNQILDMNKS
                     LNEGAILLSGFGVGSWHWNIFAESGFFDINKRICDYSEVELEKFLHGKAEKIKIENAG
                     QTNMTYEGLMVKFNRLYLSREGEISEATKKKLSKLLIEDRCPICDGRRLNERVYRSLI
                     NGYNIADLTSMQIDELAEVIKSIDEPEAQPLIKGIIEKLNSIIDIGLGYLTLDRETSS
                     LSGGESQRIKMVKYLNSNLVDLMYIFDEPSVGLHPKDVYKLNNLLKKLRDKGNTIIVV
                     EHDPDVIKIADHIVDVGPKAGKYGGEVVYEGSYENLLTSGTLTGNALSKFLPIKESVR
                     EHSGYLEVKNCNKNNLKNVSIKIPKGVLTLVTGVAGAGKSTLIKDEFLKQNPSAVLID
                     QSPVSANSRSSLATYSGIMNNIRSIFSKTNGVNASLFSSNSEGACDNCKGSGIVEMNL
                     AFMESIKSTCNVCEGKKFKKEVLEYRFQGKNIIEVLEMSVLEAIEFFNLKQIKTKLQC
                     IEKMGIGYLTLGQTLDTLSGGECQRLKLASELNKESSVYILDEPTTGLHMADIENFIS
                     IIEEIVDNGNTVIIIEHNIDVIKRADWIIELGPEGGTKGGRVIFEGIPKQLCNNKISL
                     TAKYIV"
     gene            14895..16430
                     /locus_tag="PC494_002409"
     CDS             14895..16430
                     /locus_tag="PC494_002409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HDF3912904.1"
                     /translation="MINDILTLLSERSDFFIKLSIEHLMISIISIIIAIVLGGIIGII
                     VSEFHNSSKPILGTINFLYTIPSISMLGFLIPFSGIGNTTAVIALTIYALLPMVRNTY
                     TGITNVDKNILEAARGMGSTDFQILYKIKLPLALPVIMSGIRNMVIMTIALAGIASFI
                     GAGGLGVAIYRGITTNNTIMTITGSILIALLALIFDFILGLVEKFFQRKRKKKNRKKV
                     FAILGSLILIATIFTSYLFNPSKTQTIHIATKPMTEQYILGEMLDILIEKNTGLNVEI
                     TQGVGGGTSNIQPAMENGEFDIYPEYTGTGWNMVLKKNELYTESMFSKLQSEYKTKLK
                     MQWTGMYGFSNSYALAVRKEVADKYNLKNITDLKDVSSKLTFGAEYDFYEREDGYTPL
                     CNTYGLNFKDTVDLDIGLKYQAINEGKIDVMPIFTTDGQYSVSDVVVLKDDKNFYPSY
                     QCGNVVRLEVLEENPELSKVFKMVGDILTDKEMAKMNYDVENNNLEPREVAREFLNKK
                     GLL"
     gene            16446..17207
                     /locus_tag="PC494_002410"
     CDS             16446..17207
                     /locus_tag="PC494_002410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF3912905.1"
                     /translation="MTPIIQFKNIKKQYNDKTIIDNLNLDIEKGEFLTVIGSSGSGKT
                     TLLKMINGLILPDGGNILINQTDIKNEDLIKLRRRIGYCVQGSVLFPHMTVEENISYV
                     PNLLSKKNKLEVKSAVNKWMEIVGLPNDMKVRYPSELSGGQQQRVGIARALASSPEIL
                     LMDEPFGAVDEITRKQLQKEIKEIHKKTGVTIIFITHDIYEALILGTKTLVLNHGVVQ
                     QYDTPENILNTPANQFVDQLLNIRKSIIDDDNLKE"
     gene            17545..18414
                     /locus_tag="PC494_002411"
     CDS             17545..18414
                     /locus_tag="PC494_002411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HDF3912906.1"
                     /translation="MDNNLITIEKTLDYIEKHLLDEMLDLNVISKEIGYSKYHLHRMF
                     TSVVGFSVHNYIQRRRLTEAARMLIFTEKPIIEIALISGYDTQRSFSRGFKKMFKRSP
                     NFFRRHQDFLPLQLKFDIHNRKKLRGDMVLDVKKVNCADINIVGYSGKVRKGFHIIGK
                     CWRDLHKNKEMIENKVDLGFLIGVSDYSNFKEIENTPTFTYIAGAQVATFGKLPNGME
                     KFVLPKSNYIVFTFIGKNEDSMQNVVEYIYQEWFPNSSCQFNENNLYDFVKYGEKTDE
                     NGLSEIQFWVPII"
     gene            18743..18994
                     /locus_tag="PC494_002412"
     CDS             18743..18994
                     /locus_tag="PC494_002412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3781 domain-containing protein"
                     /protein_id="HDF3912907.1"
                     /translation="MNVENELLKNLDRLHTTELGVVRIKKNLSLETNDVVNWCKTKIE
                     SPNAIINRKGKNWYISVYDCIITVNAHSYTIITAHKEKK"
     gene            19106..19885
                     /locus_tag="PC494_002413"
     CDS             19106..19885
                     /locus_tag="PC494_002413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HDF3912908.1"
                     /translation="MNDTVKEKLAESLTSDTTDILPYLPYLLQDFWELGSSPEQMLQL
                     FRKHIPFNEDTKVLDLACGKGAVSVKLAKELNIHIKGIDLIPEFIDYARRKAIEYKVD
                     ALCDFEMNDANSSVKIEHDYDCVIFGAVGDILGNYKETISKLLPTIKSKGFILIDDAY
                     VVDKSTNEQLNFERVYPTYNEWCILFKELGLKLIECIPCLELENDVEEEMNWIITRAN
                     ELIKKYPSQKDMFEQYVISQKNEYTDLQQDLVGATWILQKE"
     gene            complement(20020..20670)
                     /locus_tag="PC494_002414"
     CDS             complement(20020..20670)
                     /locus_tag="PC494_002414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3912909.1"
                     /translation="MNIVMINGSPKVNKNNSQYFLSELKQLIQNDNKVFTFKVDNTSK
                     YPDALNAILNCDRLIIASPLYVDGIPSHLLHFLEKCEKFLKTQNKKPIPVYAIVNCGF
                     NEGEHNHLAIQMIEHWCKKINFTWVQGIGIGAGEMFGSLESVPLGKGPKKDLGIALKE
                     LSKNILSDNIHIDDSNKSTIFISPNFPRFLYKLMGNHQWNTQAKSNGLTKSDILKK"
     gene            complement(20667..21170)
                     /locus_tag="PC494_002415"
     CDS             complement(20667..21170)
                     /locus_tag="PC494_002415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HDF3912910.1"
                     /translation="MRLLIHDLTDKELEKLLPKLDDNIKILPNTKEIHKCIGCFGCWI
                     KTPSECVVKDYYSNMGKLINDSDGIIIISRCCYGGFSPFVKNVLDKSINYILPYFVIK
                     DNMMRHKSRYDKQINLKAIFYGDCITEAEKETATKLVNGNAINFNIKEHSVCFYENIQ
                     DIRGESI"
     gene            complement(21219..21734)
                     /locus_tag="PC494_002416"
     CDS             complement(21219..21734)
                     /locus_tag="PC494_002416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HDF3912911.1"
                     /translation="MLEYIILGFLMEKELSGYDLKQIMSESTSYFFDASFGSIYPALK
                     RLETKGYIHYHEVIDGNKLKKLYSITNTGKEVFLEWLKKPINFSKTKQDHLVNIFFYK
                     YLPKEIIETNLKMLITEVELLLNKLSKQKNDAEENHCVDQYTYMYATMIYGVDYYNFV
                     INWCKDLLKNL"
     gene            22014..22538
                     /locus_tag="PC494_002417"
     CDS             22014..22538
                     /locus_tag="PC494_002417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HDF3912912.1"
                     /translation="MHEQIDCCERKKRTIDIKGENMRELLKWVSIINRYNTNYIDRKL
                     ADIGINNSQYFYVLHICNNPGITQDTIFEKILVNPSNITRALANLEKEGFITREPGVK
                     DKRTWHLYPTEKSLGCYDEILKITNGYVEELLSSFEKEEQELFMSMLKKVAFLAIDMN
                     EEAKLEAKENGRKI"
     gene            22522..23925
                     /locus_tag="PC494_002418"
     CDS             22522..23925
                     /locus_tag="PC494_002418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HDF3912913.1"
                     /translation="MEEKYKEPLEYEKVSKLLTKYAIPSIIAMLVSALYNIVDQIFIG
                     QGVGVLGNAATNVTFPLTTICTAIALLLGIGGASKCSLELGAKNSEKATKAAGNSICL
                     MAVFGISLFIVVSIFLTPLLKFFGSTSEILPYAHTYTKITSIGLPFLIMSTGMSKLIL
                     ADGRPKASMFCMLIGAVINTILNPLFIFVFNMGIAGSALATVIGQLISFGISVHYIKN
                     FQHIKLHKKSFKLDSIIYKHIFALGSSSCFNQLAMTVTQIVMNNTLAYYGARSVYGSE
                     IPLACVGIIIKVNMIFISIIIGISQGMQPIIGYNYGAEKYNRVKEAYKFAVGSATIIS
                     VIAFLCFQLFPRQITSIFGNGNETYFIFAEHYFRTFLFLTFINGVQIVSSTFFTSIGK
                     SVLGLFTSLTRQILFLIPLIVILPMFMGIDGVMFAGPIADAAAAMVCIYFAVHEMKSL
                     TIKQNNLMSNHNKIAEV"
BASE COUNT         8978 a         2948 c         4046 g         8203 t
ORIGIN      
        1 tttagtagtt cattttatta aattatagaa agattaatgg ttttcacttt attaaattat
       61 aaaaagttta atagtttatt acattgatat attgaaaaat tgaaggaaat aaaaatactt
      121 gtcagcaaga aataaaaatg atataagaat gaataagaga attgtaaaaa aataaaatga
      181 ttataaataa aagataaaaa tattgtaaaa aagagggtgc ctctggtgaa ttaaattcac
      241 acagagacac ctttttaatt aattttttaa attagtatat tattgtttaa ttaatagcat
      301 agtactattt aattagtcta aatttctaag gtcttccata agcttagttt tgtcagccgt
      361 tttttcatct ttcattttta taactttagc aggagaacca gcaacaacgg caccagcttc
      421 tacatcagta gttacaacag caccagctgc aacaacagca cctttaccga ttctaacacc
      481 ttcaagaata actgcattag ctcctattaa aacatcatct tcaactataa caggagtagc
      541 agaaggtggc tctaaaacac cagcaacaac agcaccagca cctaagtgaa catttttacc
      601 aagagttcct ctagctccaa taacagcatt catatctacc atagaacctt caccaataac
      661 agctcctata tttataacag ctcccatcat tacaacagca tttttttcta tagtaaccat
      721 gtctcttatt attgcacctg gctcaattct tgcatgttca cttaaagtat tttttagagg
      781 aatagcagaa tttcttctat catattctac atgagtatct gttatatcat ttccatgttt
      841 atctaatact tccattatat cctcatagtc acctacaaat atataagaac cattacttcc
      901 aaatacctta aatttatcag ttgattggaa gtgtaaagag ttagtattta catatacctt
      961 aacaggggtt ttctttttaa cttcttttat ataccttgct atttcataag catcgtttaa
     1021 atttaccatt tgttaattct ccttgtattt cattatattt cttttattat atacttattt
     1081 gtcaatttta gtatatactt acttcttatt atttatattt tatttagttt ttattgtata
     1141 gacatagtat taaataaatt tattatatat gtttgatttg tattgcgtat tattatatct
     1201 atattgcata tgtttgattt gtattgcgta ttattatatc tatattgcat atgtttaatt
     1261 tatattgtgt attattatat ttatactatt atcccaacat gctgtccata ttataaaatc
     1321 ctggtttttg cttaactaag tatttggcag cagctataga accacttgca aagataccac
     1381 gagattgagc ttgatggctt attgtaagaa cctcattgtc tccagcaaat agagcatcat
     1441 gttcgccaac aatatttcca cctcttatag catgaatacc aacttcattt ggttgtcttt
     1501 ttgcactacg accatatcta ccataattat tttcaacgtt tggcaaaacc tcttttatag
     1561 cgttagcaat cataacagct gtgccacttg gggcatctac ttttctgttg tgatgttttt
     1621 ctattatttc tatatcaaat ccttctagta atttagctgc atctttaacc aattttacta
     1681 atacatttac accaagagac atattatatg attggaatac aggaataact ttagccgctt
     1741 cacgtatttt gttcatttca tcatcattat atccagtagt agcaattact aaaggtgttt
     1801 tagtctttaa aacgtaagat aagatattat ctaaattaga gtgatgagaa aaatctataa
     1861 ctacatcagc ttcctcaact atagtactca tatcttcata aattttaagg tcgccttcat
     1921 agctatccag acctctagct gcaacacaaa ccaattctaa ttcattatct tctcttatag
     1981 tatcggctaa aatcttaccc atttttccat cataaccagt tgctataact tttaacataa
     2041 tttcctccta tgattaaggg ctaacttttg accaaactta ctttttacca tgcattaatc
     2101 tttactatgc attaactttt agtccaaagt taactaattc tttctttaat acttctaaat
     2161 ttgctgggtc catttctgct agaggtaatc ttaaatctcc aacattgaat cccaataaat
     2221 tcattgcagt cttaactggt ataggattta cttctataaa taaagctgcg attagagcat
     2281 ccataccaag ttgtaatttt ctagaacctt caatatcgcc ttcaaagaat ttagctacca
     2341 aatcgtgagt ttcttgaggg caaacattag caagtactga tataactcct tgacctccta
     2401 aagataataa aggaagtata gtatcatcat taccagagta gatagcaaag tcatctggaa
     2461 ctaaactagc tatttctgca acctgtccta ggtctccact agcttctttt acagcaacta
     2521 tgttatcaat tttagcaagt tcaactataa ggctaggact tatatttaca caagttcttc
     2581 cagggacatt gtaaagtata attggaagtt taacactgtt agctattgtt tcaaaatgac
     2641 gcttaagtcc agctttatta gctttattgt aataaggtgt tattattaat agagcatcta
     2701 ctcctaattt ttcagcttct tgacttaagt taactgagtg catagtatca ttagaaccac
     2761 ttccagctat aacaggaact cttttattaa ctttttcaac aacatactta atagtagcaa
     2821 gttgttcttc atcagtcata gtattagctt caccagtagt accacaagat actatagcat
     2881 cagtaccatt agctatttgg tattcaacta attcacctaa tttgtcaaaa tcaactttgt
     2941 tatcctttgt aaatggtgta actagagcaa cagcagaacc tttaaatatc atataaaatc
     3001 aatcccctct tttttatttt tgtgttttat attacagtta cttctaatgc ttgtttttga
     3061 gttactatta atattttaca aaattatata tttatacaag tttgtatatt atactaaatc
     3121 gtatgataaa gccatttcag ctatttgaat tgcgttagtt gcagcacctt ttcttatatt
     3181 atcagcaaca acccaaagat ttacaccatt atcaacacta aaatctcttc ttattcttcc
     3241 aacaaatact tcatctctat catcaaattc tacagcagtt ggatattcgt ttttagcagg
     3301 attatcaact actacaacac ctggagcttc ttcaagtgtt tttactaaat catctaactc
     3361 aaatggattg ttaaactcaa catttataga ttcactatga ccatttttta ctggaactct
     3421 tacagtagtt gcagttattt ttaaatcgta gttatcaagt attttcatag tttcatttac
     3481 cattttcatt tcttctttag tgtatccatt ttcagtgaat gaatctatat gaggaagaca
     3541 gttgtaagag atttgatgag ggtagaatcc agtaggatta ccgttcattc ctttctctaa
     3601 atcttcaaca cctttaacac cagaaccaga tacagcttgg taagtagagt aaacaactct
     3661 cttaattttg tatttatcat caagagcttt aaggggaacc atagcttgta tagtagagca
     3721 gttaggatta gctattatac ccttatgatt ttttatggct tctggattaa cctcaggaac
     3781 tactaaaggc acatctggat tcattctcca ttgactagag ttatctacta ctaagattcc
     3841 atttgaagca gctattggag catacttttc actaatactt ccaccagcag agaataatgc
     3901 tatttgtatg cctctaccag taaatgaagt ttcctttaat tcttctacta tatattcttt
     3961 accacaaaac attactttag aaccagctga tttagaagaa gagaataaaa atagattttc
     4021 tattggaaaa tttctttctt ctaatacttt taaaaatgtt ctacctacca ttccagtagc
     4081 accaactatt gctacattta cttttttcat ataaattcac cccaatttta aattattaaa
     4141 acattatttt attttagtta tacaagtaag atatgttaat atttttatat atccaaaaac
     4201 tttaatatta tattaacaac tttaattata tacaaaaaac gtacaaaggt atactttgta
     4261 cgtctaattt atcactcaaa gtaaaccctg tagctcatca cctacaaaaa taagtgacag
     4321 tattacacat gttatgtgca atcccagaaa atattattgc aagaaatatt ttcttcggct
     4381 gtaaatcctt tttccaatca ttaacacctg ccagctacta ttggatactc ttagttacag
     4441 ctacctctac cctaggttaa taggatatta aaatttgatt attctaataa taatacatat
     4501 ttaagaaaaa atcaacttat ttatataaat attgctaaaa tttaaatcca aaatttgtca
     4561 attcttgttt taacacatta agattagttt cttccatttc agctagagga agtcttaaat
     4621 caccaacatt aaaacctaaa atgttcatgg cagttttaac aggaactgga tttacttcta
     4681 taaataaagc agcaattaaa gcatccatat caagttgtaa tttttttgag ccttcaatat
     4741 caccttcaaa gaatttagtt actaaatcat gtgtttcttt aggacatatg ttagcaagta
     4801 cagagataac accacttcca cctaatgata atagtggtag tatagtatca tcattaccgg
     4861 agtatatagc aaagtcttta ggtactaatt tagctatttc tgcaacttga gctaagtctc
     4921 cacttgcttc cttcacagca actatattat ctattttagc aagttcagcc acaacagatg
     4981 gctttatatt cactttagtt cttcctggta cgttgtataa aataattggc aacttaacgc
     5041 tatttgctat tgtttcaaag tgaagtttaa gacctttctc attagtctta ttatagtaag
     5101 gagttattat taaaagacca tccaccccta atttttcagc ttcttgactc atatgaacag
     5161 acaacatagt attgtttgaa ccagtacctg ctataacagg tattctctta ttaacttttt
     5221 caactgtata ttttattaca gcaaaaattt cagattcact catagtagtc gcctcacctg
     5281 ttgttccaca aacaactagt gcatctgtgc cattctcaat gtgatattcg attaattcac
     5341 ctaatttttc aaagttgaca ttattatcct ctgtaaatgg ggtaactaaa gcaacagcag
     5401 aacctttaaa taacatataa tcaaatctcc ttttttatct aaatttaatt ttttaagtac
     5461 aataataatt atagtacaaa ttaattaatt ttaataggta tagttaatat cttaactgtt
     5521 taaataagat atttatatta tattaatatt agaaaaattt taaataaatg ttttattctc
     5581 aaaatatgca tattaattta ataaaatata ccaaaatgga aataaaaaat aaattttatg
     5641 agaatttaat aactaataat taatatattt aggttataat aaatatgtgc gtaaaatcta
     5701 acaataagca ataataccgt aaatttagga ggaataatat ggatacttta aaggaacttt
     5761 ttaaaatagg aagtggacct tcaagttctc atactatggg accacaaaga gcagcagaga
     5821 gatttaagaa tgaaaaccca gatgcagaaa gttttagagc aatattatat ggtagtttgg
     5881 cagccacagg gaaaggtcat ttaactgact atataattga aaaaactata gcacctaaaa
     5941 aagtcgaaat tgtttgggaa gaagatatta taaaagattt tcacccaaat gggatgaagt
     6001 ttgaagcttt agataaagat aaaaatgtaa cagctgaatg gactgtatat tctgtaggtg
     6061 gagggactat agcagaagaa ggccaaagaa acagtaaaag caatagtata tatcacttag
     6121 atactatgga tgagatagta aaatggtgca aagaaaataa taagactttg gtagattttg
     6181 tgttggaatg tgaaccaaaa gacataaaag attatataaa aactataaaa gatgctatga
     6241 gaaaatctat tgatgatgga ctaagtacag atgaaataat accaggcaag ttattattaa
     6301 aaagaagagc aagtacattt tataatgcat ataaaaaaga taagagcttc tcaacacttg
     6361 tatatgcata tgcattagca gcttcagagc aaaacgcttc tggtaatata atagttacag
     6421 caccaacttg tggttctgct ggagtaatac caggaatatt ctttgcaatg caggatttct
     6481 ataattatga tgacgaaaaa ataattgaag cactacttgt agctggaata ataggtaata
     6541 taataaaaac taacgcttca atatctggag cagaggtagg gtgtcaaggt gaagttggag
     6601 ccgcttgttc tatggcagca gcagcagtag catacttaaa aggtggaact atagaccata
     6661 ttgaatatgc ggcagaaata gcacttgaac atcatttagg aatgacttgt gaccctgtat
     6721 atggatatgt tcaaattcca tgtatagaaa gaaatgcaat ggcagctcaa agagcttatg
     6781 atgcagctaa ttatgcatta ttaactgatg gctcacattc tgtctcctta gaccaagttg
     6841 ttgaaacaat gaaagaaact ggtatagata tgatggataa gtacaaagaa acagctaagg
     6901 gtggacttgc taaacatttc ttctcttgct aaaaataaaa ttttccaata ataattcctc
     6961 tgttttgatt tatgaaacag gggaattatt attaatggtg aattatttaa taatgcaaaa
     7021 tatttttata ttcaatttag ctttttattt ttaattagta taacatgcta tataatattt
     7081 taattataaa gaaatataga aatatttttt aataaattag aaattggagg agattacatg
     7141 agagaggcat catatttaca agaacaactt tataaacata ggaagtcatt aaatcctatt
     7201 gcagagattg ggagaaaaga gtataagact tcaaaatata taagagatta tcttgataaa
     7261 ttaggaattg agtatgaagt ttatttagaa acaggtatag taggtgtaat agaaggtaaa
     7321 agacctaaaa aagatattgc ttttagagct gacatagatg gtcttcatag tgaagaaggg
     7381 gtaaaacatt tatgtggtca tgatggacat gctactatat tacttggatt aattgagtat
     7441 ttaaatgata ataaagaaga cttaaatgat aatatagtat ttatattcca accagcagaa
     7501 gaaggtcctg ggggagcaaa agctttaata gatgaaggag tgcttagaaa atacaatatt
     7561 gatgaaatat atgggcttca tatatatcca gagttaccag aaggttatgt aggtacaaga
     7621 gagggctatt ttatggctca aataggagat attgacatag aaatagtgtc taaaagtgga
     7681 catggggcta tgccacaaaa tggtattgat ggtatagtga tagcttcaaa ctttgtaagc
     7741 tcacttcaaa ctatagtgtc tagaaatata agcccaatag acaatgcagt gttgactatt
     7801 ggtagaattg aagggggagc tagaagaaat ataatagctg aaaatataaa gatggaaggt
     7861 actatgagat gtttcagccc agaagtgtat gagaaaatga agcttagagt tagagaactt
     7921 gctagagggt ttgaattggc ttataactgt aaggttaata taaatattat agatgattat
     7981 attgctgtta aaaatgacaa ggatttgtat caagagtttg tagaggctat tggaagtgat
     8041 attgttgtag agttagagcc acttatgata tcagaagatt tttcttatta tcaaaaagaa
     8101 gttccaggat tattttttat gttgggttca agaaacgaag aaaaaggatt tgtaaatggt
     8161 cttcataata taaactttaa ttttgatgaa aagatatgtg taaatgcatt gaatgtttat
     8221 tcaaaattat taaaatacaa agaagcaata gattaggaag ataagttata aagattaaaa
     8281 agcataaata cctaaattta aaaaaagtgt attaataaat accccttaca tatttgtata
     8341 aatttatttt aattgacaaa aatacaaata agaaggggtg atttttttga aagaaaaagt
     8401 acaaagagaa aagaagataa ctaatggcaa gaatactaaa atattgacaa atgatgatat
     8461 aatgaaatat gagatagcct cagaactagg tcttatggat aaagttggtg aacgtggatg
     8521 ggcaggactt acagctaagg aagcaggaag aattggaggt atgcttacat cacgcaaaaa
     8581 gaggcttaaa aagattgtgg aggagcagaa taaaaaggat gagtcaatat agtgattttg
     8641 cgtttgtata tgatgaactt atgaatgaag ttgattataa tggttgggtt aaatatatag
     8701 aagatataat agatagtgaa ggtgtaaaag taaaaaatat attggaattg gcatgtggca
     8761 cgggtaatct tacaattcca ttgactaaaa aaaattacga tatagctggt atagatatat
     8821 ctgatgagat gcttagtgta gcaagagaaa aggcagaaaa agaaggagta gaattagttt
     8881 tacttcaaca agatatatca gagcttgatt ttgaaatatc tgatttggac tgtgtacttt
     8941 gtgcttgtga tggatttaat tatataactt atgatgatga tttggaaaat atattttcaa
     9001 agacatatga attattaaag aaagatggaa tattcatatt tgatataagt tctttttata
     9061 aattagccaa catattggga aataacatgt atggagaaaa tagagaagat atagcgtata
     9121 tgtggcaaaa ttactttgat gaagaagaga atctaattga aatggaactt acattcttta
     9181 ttaaagatga atgtggaaag tttgaaagat ttgaagagat acaccaacaa agagcatata
     9241 ctgaagatga gatagttgat atgcttgaaa aatctggatt taaggatata aaatattatg
     9301 gggattttac atttgacaaa cctagtgaag aaagtcaaag aatcttcttt gtatgtaaaa
     9361 aataagatat tcttgactat ataagataat tattaaaaat aaccatgata taaaaatata
     9421 gaaaatgcag ttttatagat taaaagtaaa gtgatgatac tttatgactt ttatttttta
     9481 ataattataa agttctatag ataaaaatta aaatatagta actattactt agtaaaatta
     9541 aaataaaatg ggttttgccc aaggttaaga tagataagta tttatagata aattaaggta
     9601 gtaatataat aaaaataaga caattaacgg gacatggagg aatattaatg agagattatg
     9661 tactaagagc gacatcagga aatggtcaag ttagagcatt tgtcgcaact actagaaata
     9721 cagtagaaga agctagaaga ttacatgaaa ctacaaaagt agcaacagca gcacttggaa
     9781 gaacattaac agccacatct ataatgggat taatgatgaa aaatgatagt gataaattga
     9841 ctgtaataat aaaaggtgga ggtccaattg gaactattat cgccacatca gattctaagg
     9901 gaatggtaaa aggatatgta ggaaatccac aagtagaggt tgaagactat ccaaatggaa
     9961 agttaaatgt agcagcagca gtaggtacag aaggtgttgt aaaagttata aaagatttag
    10021 gtcttagaga accatataat gggacttatc cattggtaag tggagaaatt gcagaagact
    10081 ttacttatta ttttgctgta tcagagcaga ctccatcagt agtagcttta ggtgttctta
    10141 caaaagaaga tgaagtagag tttgctggag gatttatagt tcaattaatg ccagatgcag
    10201 aagaagagac tattgctaag ttagaggaaa atgtagctaa attaccttct ataactaaca
    10261 tgttaaaaga aggaaaatca ccagaggata tattaaatat tgttttggat ggtttggaac
    10321 ctaaaatact tgatacctgt gaagttgggt ttatatgtga atgttcaaaa gaaagagtaa
    10381 aaactgcttt ggttgcaatt ggtaaaaaat cattggctca aataatagaa gaagataaaa
    10441 aagcagaagt tggttgccag ttctgtaata agaagtatat gtatagtgaa gaagagttgc
    10501 ttgaaatttt aaaggaaatg tagactataa aaatagttgt attgatataa gtaatgttat
    10561 agtgatatag taaagtcgta ttgatatagt aattaaagta taatttatta ataatagacg
    10621 tatttatatt aaaaaataag tttaataaat ttttaagctt aataaatttt aagaattaag
    10681 aagctttctg gctgtaatgt ttgcaatgtt gcagttagaa ggctttttta ttttattata
    10741 gttcgtgtca aagattgtat gaaacaataa aatattgtaa aataatttgt atatttagac
    10801 ctgattggca caaaggttta taaggtattt gagttgatta tgcgaaattc tatgaagtag
    10861 taaccctgtg actttaatca tgggaggttc agaagaagga gaaaatttta aatatggaaa
    10921 gtaaaacgaa gtacatagga ataagtatat taatattatt gatgatattt ttaattgcaa
    10981 agaattttaa cggaaaactt gaaataccta ttcctgagag taatagtaga aaatttaaat
    11041 cagcagcagt gttttatcct caacatcaag atgatgaggt tttatgggga ggaagtgcca
    11101 ttgtagatgc tataaaacag tgtggtgttg ataatgtata tgtggtatta gtatcagatg
    11161 gttctggagt taacgttttc aaagctaaca caaaatttag aaatttaact aggaagcaaa
    11221 aggaagagct tagaaataac gagtttaaat cagctttgag agagcttgga gtgaaacctc
    11281 aaaatgtgat tatacttgca gatatagata aaaaggaagg cacacattat gaattaatgg
    11341 aaaagactat attggatttt gaacataagt ttaaaggcaa tgtgacccat atagcccatc
    11401 actataagta tgatgaccat ataatgcata gaaagaatgg ggaagtttta aagaaactta
    11461 aacgtgaagg taagataaaa gatgacttgt attttgttaa gccaaaatat gtaaagtata
    11521 taccaagaaa tgaaagagct atctataaag caatggattt tgatgactac aataaggtta
    11581 agagtgcttg ttatgaatat aaggttgtaa attcaaagcg taaaatgtat ggtataggat
    11641 atatttcggc acatagttat tttgaacatc ttctaaatga ccctgaactt acgtctgtat
    11701 taagtgaaga ttaatttctt ataagtagta agttatgttt gataagttga ttggaatttt
    11761 ctatagtttt gaaggtattg gaaatttagt tttatttaaa gatttaaaga tagaggtttt
    11821 tagtgtttaa aattttaaag ttaagttgaa taattgtata gaattatttg tgaaagaaga
    11881 aacagtgtaa aacatagtat cttatttatg gttttaaaat cataggcaag atactttttt
    11941 tatgtaacta ataccatttt gagattatta acttaagaat tttatataat ttaacactca
    12001 tatataatga tgatatttag gtagaataga tgcaattacg cttaaataaa ataactgtat
    12061 tttttataaa aatcaaaccc tacactatac taccagataa aatctacatg ctataatttg
    12121 acctgtgttt ataaaaaaag gagtaatcta ataaaatagt atttcactta tgtataacta
    12181 acaactatta ttacgatttt ctctaaataa tttaaagaaa aataatgcag gaggtaaaat
    12241 atgaacaatg aatttataat tttaaaaggt tgcaaagaga acaatttgaa caatatttcc
    12301 ttaaaaatac caaaaagaaa aataaccata ttcacagggg tgtcgggttc tggaaagtca
    12361 tctattgtat ttgagacaat tgcaaaagaa tcacaacgcc aactaaatga aaggtttagt
    12421 acatttgtaa gaagtttttt acctaagtat ggagaggtta aagctgattg tatagaaaat
    12481 ttgtcaacac caattatcat agaccaaagt agacttggtg gaaattcaag gtcaacccta
    12541 ggtactatta cagatgtaaa ttccttttta agagctttat attcaaggtt tggtagtgag
    12601 tatataggta atgctaatat gttttctttt aataatattg atggtatgtg cccacactgt
    12661 catgggcttg gaaaaaagct agttcctaat atgaaccaaa ttcttgatat gaataaatca
    12721 ttaaatgaag gtgctatatt gctttcaggg tttggagtgg gttcttggca ttggaatata
    12781 ttcgctgaat caggattttt tgatattaat aagaggatat gtgattattc agaagtagaa
    12841 ttggaaaagt ttttgcatgg taaagcagaa aagattaaga tagaaaatgc tggtcaaact
    12901 aacatgacat atgagggatt aatggttaaa tttaatcgcc tatacttaag tagagaggga
    12961 gaaatatctg aagctactaa gaaaaaattg agtaaacttc ttatagaaga tagatgtcct
    13021 atatgtgatg gaagaagact taatgaaaga gtatataggt ctttaattaa tggttataat
    13081 atagcagatt taactagtat gcaaattgat gaattggctg aagttattaa aagtatagat
    13141 gagccagaag cacaaccttt aattaaagga ataatagaaa agttaaacag tatcatagat
    13201 ataggtcttg gatatttaac actggataga gagacatctt ctctatcagg aggggaatct
    13261 cagcgtataa agatggttaa gtatttaaat agtaatcttg ttgatttaat gtatattttt
    13321 gatgaaccaa gtgtaggact tcatccaaaa gatgtgtata aattaaataa tcttttaaaa
    13381 aaattgcgtg ataaagggaa tacaattata gttgttgaac atgacccaga tgttattaag
    13441 attgcagacc atattgtaga tgtaggacca aaggcaggta agtatggtgg agaagttgtg
    13501 tatgaaggca gttatgaaaa tctacttaca agtggtactt tgacagggaa tgctttaagt
    13561 aaatttcttc ctattaaaga aagtgtaaga gaacatagtg gatatttaga agttaaaaat
    13621 tgtaataaaa acaatttaaa aaatgtatcg attaagatac ctaaaggtgt attgactcta
    13681 gttactggag tagcaggagc aggtaaaagt acgttgatta aggatgaatt tttaaagcaa
    13741 aatcctagtg ctgtacttat agaccaaagc cctgtttcag caaattcaag gtcgagtttg
    13801 gcaacatata gtggaattat gaacaacata agaagcatat tttcaaaaac aaatggcgta
    13861 aatgcttctt tattcagttc aaattcagaa ggagcttgtg ataactgtaa gggttctgga
    13921 atagtagaaa tgaatcttgc ttttatggag agtataaaga gtacctgcaa tgtttgtgaa
    13981 ggtaaaaaat ttaaaaaaga agttttagaa tataggtttc aagggaagaa tataattgaa
    14041 gttcttgaaa tgtctgtttt agaggcaatt gagtttttta atttaaaaca gattaaaacg
    14101 aaattacaat gtattgaaaa aatgggtatt ggatacctta ctttaggaca aactcttgat
    14161 actttgtctg gaggagagtg tcaaagatta aagcttgcta gtgaattaaa taaggaaagt
    14221 tcagtgtata tattagatga accaacaaca ggtcttcata tggctgatat tgagaatttt
    14281 ataagtataa ttgaagagat tgtagataat ggaaatacgg tcataataat tgaacacaat
    14341 atagatgtaa ttaaaagagc tgattggatt attgagctgg gacctgaagg aggaacaaaa
    14401 ggcgggagag taatatttga aggtattcca aaacaattat gtaacaataa aatatcatta
    14461 acagcaaaat atatagtata ataaataaaa tataataaaa ttataatgat attttaataa
    14521 atataatggg tatataaaat gataattaaa cttaacagta ataaataatg tgagaaatat
    14581 tcaaatttaa ttaaataaag tgtcagaaat ttgtttaaat tttagtattt taacggttct
    14641 gacctttttt cttattttta tggagaatat cgaggatgga gtctctaata gttacttttt
    14701 tgtgtctact tgcaagtttg attaaaaaat ggctatacac acttgtgact tcagtcatgg
    14761 gaggttcaga ttataatctt aatatataat ttgtgaaata atttgatgac gatttgctga
    14821 tgtataaaca ataaagatta actacattaa aatttaaatc ttgttaagta aaacttataa
    14881 aaggagagag atggatgata aatgatattc taaccttatt atctgaaaga agtgattttt
    14941 ttataaagct atccatagaa catttgatga tttctattat ttctataata attgcgattg
    15001 ttttgggtgg tataattggt attattgtaa gtgaatttca taattcttct aaacctatat
    15061 tgggaactat caattttcta tacaccattc catctatttc tatgctagga tttctgatac
    15121 cattttccgg aattggaaat actactgctg ttattgcact taccatttat gcattattgc
    15181 caatggttag aaatacatat actggaatta ctaatgtgga taaaaatatt cttgaagcag
    15241 ctaggggaat gggaagtaca gattttcaga tattgtataa aataaaactt ccgttagccc
    15301 tacctgttat tatgtctggt attagaaata tggtgattat gacaattgca ttagctggta
    15361 tcgcttcatt tataggtgct ggaggtctag gtgtagccat atatagagga atcacgacaa
    15421 ataacacaat aatgacaatt actggaagta tacttattgc tctattagct ttaatatttg
    15481 attttatttt agggctggta gaaaaatttt ttcaacgaaa aagaaaaaag aaaaatagga
    15541 aaaaagtttt tgccattcta ggaagcctta ttcttatagc aactatcttt acgtcttatt
    15601 tatttaatcc ttcaaagact caaactattc atattgctac taaacctatg actgaacaat
    15661 atattcttgg tgagatgttg gatattttaa ttgaaaaaaa cacaggtcta aacgtggaaa
    15721 ttacacaagg tgtaggaggg ggaacatcta atatccagcc agctatggag aatggagaat
    15781 ttgacattta tccagagtat acaggtacag gctggaatat ggtacttaag aaaaatgaat
    15841 tatatactga aagtatgttt agtaaactac agtcggaata caaaactaaa cttaaaatgc
    15901 aatggactgg tatgtatggt ttttctaata gctatgcatt agcagttaga aaagaagttg
    15961 cagataaata caatttaaaa aatataacgg acttaaaaga tgtatcttct aaattgacat
    16021 ttggagctga atatgacttt tatgagagag aggatggata tactccattg tgtaatacat
    16081 atggactgaa ctttaaagat acagttgatt tagatattgg attaaaatac caagctatca
    16141 atgaaggtaa gattgacgta atgcctatat ttacaactga tggtcagtat agtgtttcag
    16201 atgttgtagt tctaaaagat gataaaaatt tctacccatc ttatcaatgt ggaaatgttg
    16261 ttcgtttgga agtattagag gaaaatccag aactatcaaa ggtatttaag atggttggag
    16321 atattttgac tgataaagaa atggctaaaa tgaattatga cgtagaaaac aacaatttag
    16381 aacctagaga agttgctcgt gagtttctga ataagaaagg tcttttataa attggaggaa
    16441 atataatgac acctattata caatttaaaa atattaaaaa acaatataat gataaaacta
    16501 taatagataa tcttaattta gatatagaaa aaggagagtt tttgactgta attggttcgt
    16561 ctggttctgg taagacaaca ctcttaaaaa tgattaatgg tctgattttg ccagatggag
    16621 gaaatatttt gataaaccaa acagatatca aaaacgagga cttaattaaa ttaagaagaa
    16681 gaataggata ttgtgtacag ggaagtgttc tttttcctca tatgactgtt gaagaaaata
    16741 tttcatatgt accaaatctc ctaagtaaaa agaataaatt agaagtaaaa agtgctgtaa
    16801 acaagtggat ggaaatagtg ggattgccaa atgatatgaa agtgcgttac ccatcagaat
    16861 tgtcaggtgg tcagcaacaa cgtgtaggga ttgcaagagc tttagcttct tctccagaaa
    16921 ttttattaat ggatgaacct tttggtgcag ttgatgagat tacacgaaag caattacaaa
    16981 aagagataaa agaaattcat aaaaaaacag gagttacaat tatctttatt acgcatgata
    17041 tttatgaagc tttgattttg ggaacaaaga ctttggtatt aaatcatgga gttgttcaac
    17101 agtatgatac tcctgagaat attttaaata ctcctgctaa ccaatttgta gaccagttat
    17161 tgaatataag aaaatctata atagatgatg ataatttaaa agaataaatt taaatttaaa
    17221 atcaaattgt tgtgataaaa actattgatt tagagctaac ttcaagttgt atacttgaag
    17281 tggaaaagtt agattaaggt atagaagggc atttagcagt tggctgtaga cgaggtaact
    17341 gctgaaggtg ctttcaataa atggctagaa cctgtatctg ttgaagatta taataaattg
    17401 aaataagaag ctcaatatac agagtagata ggcacttcaa atagaagtgt cttttgtgtg
    17461 ccataaaata aatcaaaata ttagcaaaga atgtgaaaaa caaaataaaa taatatgcta
    17521 tctttaaaat aggagggatg ctatatggat aacaatttga ttaccattga aaaaacttta
    17581 gattatatag aaaaacatct tttagatgag atgttagatt taaatgtaat ttctaaagag
    17641 ataggctatt caaaatacca tttacataga atgtttacat cagttgtcgg atttagtgta
    17701 cataattata tacaaagacg tagacttact gaagcagcga gaatgctaat ttttacagaa
    17761 aaaccaatta ttgagattgc tttaatctcg gggtatgata cacaacgctc tttttcaaga
    17821 gggtttaaaa aaatgtttaa acgtagtcct aattttttta gaagacatca agatttttta
    17881 ccactacaat taaaatttga tattcataat agaaaaaaat tacgtggaga tatggtttta
    17941 gatgttaaaa aagttaattg tgcagatata aatattgttg gctattctgg taaagtaaga
    18001 aaaggatttc atattattgg aaaatgctgg agggatttgc ataaaaataa agagatgata
    18061 gaaaataagg tagatttagg ttttttaatt ggagttagtg attatagcaa ttttaaagag
    18121 attgagaata ctcctacatt tacatacatt gcaggtgctc aagtagctac ttttggcaaa
    18181 ttacctaatg gaatggaaaa attcgtatta ccgaaaagta attatattgt ttttactttt
    18241 attgggaaaa atgaggatag tatgcaaaat gttgtagaat atatctatca agaatggttc
    18301 cctaattcaa gttgccagtt taatgaaaat aatttatatg actttgtaaa atatggagaa
    18361 aaaactgatg agaatggttt gagtgaaatt cagttttggg ttccaatcat ttaaaagaag
    18421 gtattatgta taaagtagat ggatttatat aggcaaagtt ttacagcagt atgtatttat
    18481 aaataattta tagtttgtag gaaagaaata attttactat aagattatga taaaatacac
    18541 aatactatga caaaatagtg ttaaataata gatttaattt tgcataggaa aagttctata
    18601 atggtgtgta ttcataaata atttataatc tgtaggaaag aaatagtttt actataagat
    18661 tatgataaaa tacacaatac tatgataaaa tagtactaaa taatagattt aattttgcaa
    18721 aggataaagt gttttaataa aaatgaatgt agaaaacgaa ttacttaaaa acctagatag
    18781 attgcataca acagagttag gcgttgtaag aattaagaaa aatctttctt tggagacaaa
    18841 tgatgtagtg aactggtgta aaactaaaat agaatctcca aatgccatta ttaatagaaa
    18901 gggaaaaaac tggtatataa gtgtatatga ttgtattata acagtaaacg ctcacagtta
    18961 tacaattatt acagctcata aagaaaagaa atgaattgca aaatacaaag gtcaaaagca
    19021 ttttccactg tttgtagtac ctatgaagaa gtatataaaa taatattact tttgaataat
    19081 aatttaaatt ttggaggttg aaaaaatgaa tgatactgta aaagaaaaat tggcagagtc
    19141 actaacttct gatactactg atattttacc ttatttgcct tatttattac aagatttttg
    19201 ggaattagga agttcaccag aacaaatgtt acaattattt agaaagcata taccttttaa
    19261 tgaggataca aaagttttgg atttagcttg tggaaaaggt gctgtatctg tgaagcttgc
    19321 aaaagagttg aatatacata tcaaaggtat tgatttgata cctgaattta ttgattatgc
    19381 tagaagaaag gctattgaat ataaggttga tgctttgtgt gattttgaaa tgaatgatgc
    19441 taatagttct gtaaaaattg agcatgatta tgattgtgtg atttttggag ctgtagggga
    19501 tattttaggt aattataaag aaactataag taagctatta cctacaataa aaagtaaggg
    19561 gttcatttta attgatgatg catatgtagt agataaatct acaaatgaac agcttaattt
    19621 tgagagggtg tatcccactt acaatgagtg gtgtatattg ttcaaagaat taggtctgaa
    19681 gctaattgaa tgtataccat gtttagaact tgaaaatgat gttgaagagg aaatgaattg
    19741 gattataact cgtgcaaatg agctaattaa aaaatatcct tctcaaaaag atatgtttga
    19801 acaatatgtt attagccaaa aaaatgaata tactgattta cagcaggacc ttgttggagc
    19861 aacttggatt ttacaaaaag aataagataa atattagact agataatcaa tgttatagtg
    19921 aattatccca tgtctagtga atataaataa cataaaaaac cgtcaagatg aatagtttat
    19981 tcgtgcttga cggtttttag tatttgttga agtaaaattt tatttcttta gtatatcact
    20041 tttagtcaat ccatttgatt tagcttgagt attccattga tgattcccca taagtttata
    20101 taggaatcta gggaagttag gtgaaataaa aatagtactt ttgttggaat catctatatg
    20161 tatattatca ctaagtatat tttttgaaag ttcttttaat gcaattccta aatctttttt
    20221 aggtccttta cccaaaggta cggattctag tgaaccaaac atctccccag ctccaattcc
    20281 aataccttga acccatgtaa agttgatttt tttacaccaa tgctctatca tttgaattgc
    20341 caaatgatta tgttcacctt cattgaatcc acagttaact attgcataca ctggaatagg
    20401 ttttttattt tgtgttttta aaaatttttc acatttctct aaaaaatgaa gtaaatgaga
    20461 tggaatacca tctacataaa gaggagatgc gattattaat ctatcacaat taagtatggc
    20521 attaagagcg tcaggatact tagatgtgtt atctacttta aatgtaaaaa ctttattatc
    20581 attttgaata agttgtttta attcagataa aaaatactgt gaattatttt tatttacttt
    20641 tggactacca tttatcatta ctatattcat atggattcac ctcttatatc ttgtatattt
    20701 tcatagaaac aaacagagtg ttcttttata ttgaaattta tagcatttcc atttactaat
    20761 ttcgtagcag tttctttttc agcttctgta atacaatctc catagaatat agcttttaaa
    20821 tttatctgtt tatcatatct gcttttatga cgcatcatat tatcttttat tacaaagtat
    20881 ggaagaatat aattaatgct tttatcaagt acgtttttga caaaagggct aaaccctccg
    20941 taacagcatc tgcttattat aataattcca tcagagtcat ttataagttt acccatgttg
    21001 ctgtaataat cttttacaac acattcagaa ggagttttaa tccagcaacc aaaacaacca
    21061 atacatttgt ggatttcttt tgtgtttgga agtattttta tattgtcatc aagtttgggt
    21121 aataactttt ctaattcttt gtcagttaaa tcatgtatta aaagcctcat aaagtccatc
    21181 tccttttatt atgtatgttt acttctaaaa attatatctt atagattttt cagtaaatct
    21241 ttacaccaat taataacaaa attataatag tcaactccat aaatcattgt tgcatacata
    21301 tatgtatatt ggtcaacaca atgattttct tctgcatcat ttttttgttt acttaattta
    21361 tttagaagta attctacttc agttattaac atttttaagt ttgtttcaat tatttctttg
    21421 ggtagatact tgtaaaagaa tatattaaca aggtggtctt gctttgtttt agaaaaattt
    21481 ataggtttct ttaaccattc aagaaatact tctttaccag tattagttat ggaatatagt
    21541 ttttttaatt tgttaccatc tataacttcg tgatagtgta tatatccttt tgtttctaat
    21601 cttttaagtg caggatagat acttccaaag ctggcgtcaa aaaagtacga ggtactttct
    21661 gacattattt gttttaagtc gtatccactt aattcttttt ccattaaaaa tcctaaaata
    21721 atgtattcta acatattacc tcctggtatc aattagatat atatcgattc gatatattta
    21781 ttattacaga taataaatct tacgtcaaga tgctttttaa gataagctaa aaagaattag
    21841 gagttattga taaatatgca aaaaaattaa tataaaaggt aattaaatat caataaagat
    21901 ttaaaaatag ttaaatcaaa gtaagagtct aatatataaa atttatagta actttatggt
    21961 ttaaatataa acttgtgtgc tattgacaaa gtataaaatt agcagtagaa taattgcatg
    22021 agcaaataga ttgttgcgaa cgcaaaaaaa ggacaataga tattaaagga gagaatatga
    22081 gagagctatt aaaatgggtt tccattataa atagatacaa tacaaattat attgacagga
    22141 aattggcgga tattggaatc aataatagcc aatattttta tgtattacac atatgtaata
    22201 atccaggtat tacacaggac actatatttg agaaaattct tgtgaatcct agtaatataa
    22261 caagagcttt ggcaaattta gaaaaagaag gctttataac aagagaacca ggtgtaaagg
    22321 ataaaagaac atggcattta tatcctacag aaaaatcttt aggatgttat gatgaaatac
    22381 taaaaataac aaatgggtat gttgaggagt tgttgagttc atttgagaaa gaagagcaag
    22441 agttgtttat gtcaatgtta aagaaagttg catttttggc tattgatatg aatgaagaag
    22501 caaaattgga ggcgaaggaa aatggaagaa aaatataagg agccattgga atatgaaaag
    22561 gtttcaaagt tattaactaa gtacgcaatt cctagtatta tagcaatgtt agtaagtgct
    22621 ttatataaca ttgttgacca aatatttatt gggcaaggtg ttggtgtatt gggcaatgct
    22681 gctacaaatg tcacttttcc actaacaaca atatgtactg caattgcatt attgttagga
    22741 attggaggag cgtctaagtg ttcattggaa ttaggtgcta aaaattcaga aaaagctaca
    22801 aaagcagcag gaaattctat atgcttgatg gctgtttttg gaataagttt atttatagta
    22861 gtatcaatat ttttaacacc actattaaaa ttctttggct ctacatcaga aatactacct
    22921 tatgcacaca catatacaaa aattacatca attggattac catttcttat aatgtccact
    22981 ggaatgagta agttgatact tgcagatggg agaccgaaag cttctatgtt ttgtatgtta
    23041 ataggagcag ttattaatac aattttgaat ccattattca tttttgtttt taatatggga
    23101 attgctgggt ctgctttagc aactgttatt gggcaactta tatcttttgg aataagtgtt
    23161 cattatataa agaattttca acatattaaa ttacataaga aaagttttaa attagatagt
    23221 ataatttata aacatatatt tgcgctaggt tcaagctcat gttttaatca attagcaatg
    23281 actgtaacac agatagttat gaataataca ttggcatatt atggggctag gtcagtttat
    23341 ggaagtgaga ttccacttgc ttgtgtcggt atcattatta aagtaaatat gatttttata
    23401 tctataatta ttggtatatc acaaggtatg caaccaatta tagggtataa ttatggggct
    23461 gaaaagtata atcgtgtaaa agaagcatat aagtttgcag tgggaagtgc aactattata
    23521 tctgttattg cattcttatg tttccaatta ttcccaagac aaattacgtc tatatttggt
    23581 aacggaaatg agacttattt tatatttgca gaacattatt ttagaacttt cttgttctta
    23641 acatttataa atggtgttca aatagtatca tcaactttct ttacatcaat tgggaaatca
    23701 gtgttgggac tttttacttc tttgactcgt caaattttat ttttaattcc attgatagta
    23761 attttaccaa tgtttatggg aattgatgga gtaatgtttg caggaccaat agcagatgca
    23821 gcagcggcaa tggtatgtat atactttgca gttcatgaaa tgaaatcatt gactataaag
    23881 caaaataatt tgatgagtaa ccataataag attgcagagg tataagacaa tatttaagaa
    23941 gtatagaaaa ttaatttaaa gaagtataat aaactaattt aggaagtata gaaaattaat
    24001 ctaaagaagt ataataaact aatttagaaa gtatagaaaa ttaatctaaa gaagtgtaat
    24061 aaactaattt aggaagtata gaaaattaat ctaaagaagt gtaataaact aatttaggaa
    24121 gtatagaaaa ttaatttaaa gaagtataat aaactaattt aggaagtata gaaaa
//
LOCUS       DAMKNB010000054        23821 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.056, whole genome shotgun sequence.
ACCESSION   DAMKNB010000054 DAMKNB010000000
VERSION     DAMKNB010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 23821)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23821)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23821
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.056"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            305..475
                     /locus_tag="PC494_002419"
     CDS             305..475
                     /locus_tag="PC494_002419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3912914.1"
                     /translation="MSALLYGVCNKSISVSIVINMQEFKIGVSMAYGVLVIGICYIAL
                     GIIFKLDRKRFT"
     gene            1018..1896
                     /locus_tag="PC494_002420"
     CDS             1018..1896
                     /locus_tag="PC494_002420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketose-bisphosphate aldolase"
                     /protein_id="HDF3912915.1"
                     /translation="MLINMKEMLKVAQENQFAVPAFNIGSGQILKAVVQSANEKNAPV
                     ILAIHPNELSFLGDSFVASCIEEANKSKVPMVIHLDHGENKEQILRAIRCGFTSVMID
                     GSHLPYEENVAISREIVEIAKGLNVSVEGELGTIGTTGTSSEGGTDEIIYTDSKLAKD
                     FVEKTGVETLAIAIGTAHGIYPKGFKPELKLDLLKEIREVVDIPLVLHGGSSNPDEEI
                     AQAVKLGVCKINISSDVKSAYYKKCRELLEQNPSLYEPDTIYPPCIKSAREVIEFKMN
                     LFNAIDKLKCFYKNKN"
     gene            1932..3827
                     /locus_tag="PC494_002421"
     CDS             1932..3827
                     /locus_tag="PC494_002421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDF3912916.1"
                     /translation="MIGKILRSDCIVLDKQLQTKKDVINYMANHLYHGNYINNKEKFI
                     ADINKREKESSTNMGNLIAIPHAKSNVVNQPVMMYLRTDREITDNDGQKLRSFFMIAV
                     PESGSDEHLKIISKLATYLMEENFLKHLLSAETPYEILSIFNNKAAESGDFSNNQNKG
                     LIVGITGCPTGIAHTFMAKKALEEAGQELGYEVKIETHGAIGVENKLTKEDIKRAEYV
                     IIACDKEVQLSRFIGKKVLQKKVVDAKNVSLAKNLIINAENGMAKEIKPGGKTLEDSK
                     EMLQGSEKKGVYKHLMSGVSEMIPFVVIGGIGIAIAFMFGIFASDPTHETYNPIAGFF
                     GQLGGDSAFKLFIPILAGFIAKSIAGRQGFAPAMIAGFMAVIGGSGFIGGMVAGFATG
                     YIALGVMKITENLPDVLKGVNAVLICPLLIAFTSGAIMFFVVNTPASWLNEALQSWLQ
                     SMSGTNKVLLGAILAGMMASDMGGPINKTASAFGLAMFSSNIFEPSAALMVGGMVPPL
                     AISLAMLIFKNKFTKEERKSSLPTAIMGASFITEGAIPFAAADPLRMIPANIIGSCIG
                     GAICMSLDITLMAPHGGIFVIPFACSAPVAYIACILIGTVITALIIGVTKPTIRSENS
                     EVELLGA"
     gene            4095..6002
                     /locus_tag="PC494_002422"
     CDS             4095..6002
                     /locus_tag="PC494_002422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HDF3912917.1"
                     /translation="MLVSRQIEFLKLILNENKYRPIKYFKDKLNVSDKTLQKDLKMIE
                     KYLETFNIKIDIKRGYGILIEDLAKKNIDLINSLNIQSKENKSLSVEQRRMEILKYLL
                     LNSNNITSINQLADKYYVSKTSIVNDFKYIEAWIKEYNLKLNKTLEGTKIIGKEVDIR
                     KSIAKMMDDLLDENYEQHDISELTRLDSATFSALINLFDIDSIIFVETIITELEYNLG
                     YTINQPYYINLITHILICLKRIEEGNQIESQEEREISVDNLDELVYKNVSTLIDKIEN
                     RYRVKITKDEIMYIYIFLVSSGFSSENNSSYNDESDRLSESEKVSSIMIENMSRFLNI
                     NLKNDDLLQKSLASHVRPMLNRLRYDIQIKNPLLGEIQERFSDVLGLCMMTINIMTEY
                     DNLKNISIDEVSYLATYFQAAIERNMSSKRVIVVCHTGYGTSQLLAARLKREFPEWTI
                     VDIVPMHQLSKRNLDDVDFVISTVNLDLKDKLHIVVSVLLMENDINNIKNALLSKPKK
                     SMNLDTNLLGMYLEDNIYFNFDVAQMESLIGVNLGSKYESISLGKDLNIYIHKQSKLN
                     KGIMNINNVTRTIDIYLEISNQSFLKNILMEISNLYRQKNYINYIIDCKSKEDIKILF
                     KNNLLEKTNGN"
     gene            5992..6441
                     /locus_tag="PC494_002423"
     CDS             5992..6441
                     /locus_tag="PC494_002423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDF3912918.1"
                     /translation="MEIREILTEESIILDLKSTTKEGIIQELVDKLYDTGSITLKSKF
                     IKALKHREKIGSTSIGYQMAMPHGKTKYVKKASIVIGKSKKGVDWPSIDGLPVKVIIM
                     FAMPQSGGNEDMILISKIAYILGGKNIGERLLNANTKKEILDIFYEV"
     gene            6541..7428
                     /locus_tag="PC494_002424"
     CDS             6541..7428
                     /locus_tag="PC494_002424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HDF3912919.1"
                     /translation="MAIYLEMPKLIHEFPFRSLSNEGEVLTTPHWHKEIEILLITEGV
                     VNLFINDKPMQLKKGEIVIIKGGDIHYILPSPGSERLVFQFDISFFNDLILLNEEKES
                     LINLFSSIKKCSRDWSAKIRKSVFDILIDIYNEDLYKIEGYSYAIKGKMYNLIPILYR
                     QIPREIEENTVEYEINSKEILERLNNIFKYVEKNYKQPIKLEDVSYEVGFSVYYFTKF
                     FKKNTGKTFITFLNEYRLEKAKWILLNNNISIVDLVEEVGFGSTKTFYRVFKEKIGVS
                     PLEFKKRYNSLEKKGSVSK"
     gene            7831..9279
                     /locus_tag="PC494_002425"
     CDS             7831..9279
                     /locus_tag="PC494_002425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HDF3912920.1"
                     /translation="MKLGKDFLWGGAISANQSEGFYLDGGKGLSQFDKLPLNDKRLKD
                     VCLDEDNILNENNQYYPSHIGIKFCENYKEDIAMLAEIGFKCFRFSISWSRIFPTGEE
                     SEPNEKGLQLYDNIIKELKKYNIEPLITISHFDIPYSLVEKYSGWADRRVVNLYVKYA
                     EILMKRYKDDVKYWIPFNEMNMIMHIPYIGAGLTFIADENQLQKKYQAAHHQLLANAK
                     TIEIGRYINKEFKFGCMLAAGKTYPYTCKPEDVFATLEHERYNLFFSDVQVRGVYPSF
                     MNYYLKSNQIKLIIKEEDLSTLKDNTVDFVSFSYYSSACSSARAEGLEKSKANGPETI
                     KNPYLPKSNSVWQNDPVGLRITMNQLYERYQLPLFIVENGLGTQDIVNEDGKIIDDYR
                     IDYMKEHIKNMILGVNEDGIELIGYLMWGCIDVTSVSEGKMTKRYGIIHVDSDDYGRG
                     SFKRTKKQSAFWYKKVIETDGEILFNDMETHA"
     gene            9305..11695
                     /locus_tag="PC494_002426"
     CDS             9305..11695
                     /locus_tag="PC494_002426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HDF3912921.1"
                     /translation="MSLIFTTKDQLIEQGFSKDTIKSNETLFTLANGHLGVRGNIEES
                     DFNNEYVDNMGTYVNGFYEESPITYGESAYGYAKQNQTICKLPNAHIVNFSIEGDYFD
                     LSKGITSEHSRILDLNEGILKRSFIWENSCGRKVKVSIERLVSQDIEELMMISYTITP
                     LNFNGKIKFKNKMENSMEKFNCEKVDDPRVASINKKQFKINVKKYNNKYFMNLVTERS
                     RLGLWCGFDSYITCGNITNETYNVSDECIEREIEVYAKKDERLNLEIVVGYSRVYSDL
                     NLNEERLKSLECLESLKCLESEAHLKSLELVLREACNIGFDKVKNIQRKKMNEFWTTS
                     DVEIEGDKTLQLGIKTNLFHIYQSAGRDGKTNISAKGLTGDGYEGHYFWDTEMYILPF
                     FIYTQPSIARALLDYRYSILDASRERARELGINKGCLYSWRTINGNECSAYYPTGTAQ
                     FHINADIAYGIRTYFEATNDEEFMMQNGLEILIETARFWVEFGDYIESKNNKFCINGV
                     TGPDEYTAIVNNNYYTNLMAKYNLIYAVQMVDKFKHNLFSNEVFRKVKLQEYEVKNWI
                     NAAQNMYLPYDEEKKISKQDDSFLEKSVWDFKNTPKEKYPLLLHYHPLTIYRYQVNKQ
                     ADTVLSALLFPDEFSLEQKKRDFEYYEKITTHDSSLSRSIFGMMASEIGNHEKAYNYF
                     MDTALMDINNLQKNTSDGIHAANMGGTWMSLVYGFAGMKIKNDKLSFEPRIPKHWKNI
                     KFNILFRDNLVSVNIEEYKSYYKLIKGRNITILHDNKEIKLSKNIIEVNNCFKGSN"
     gene            11697..12368
                     /gene="pgmB"
                     /locus_tag="PC494_002427"
     CDS             11697..12368
                     /gene="pgmB"
                     /locus_tag="PC494_002427"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HDF3912922.1"
                     /translation="MKAVLFDLDGVITDTAKYHFEAWHEIAKSLDIEIDETFNEKLKG
                     ISREESLDKILLSANKVDSYTKEEKLKVCEEKNNIYIKLINSLTYKDILPGINELIKE
                     LKKNNVKLGIASASKNAPRILESLGIKDEFDCIVNPSLLKRGKPYPDIFIEGSKILNL
                     KQYDCVGIEDSYSGIKAINAANMTSIGVGKKEVLGKCDHIVEDTSLLNCNTLLQAWSK
                     KINLD"
     gene            12407..13771
                     /locus_tag="PC494_002428"
     CDS             12407..13771
                     /locus_tag="PC494_002428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HDF3912923.1"
                     /translation="MKNKYEEVAQLIIDGLGGKDNIIDLTHCMTRLRFILKDEKKVNA
                     DKLKSIDKVVGVNSTSTQYQVIIGNEVGVVFNAIINKGINTTGDIKSDIKNKKNSILN
                     NIIDTITGCMTPMIPALTASGMIKVILSLCTTFNWLSSNSSTYRVLDIIGDVAFYFMP
                     IILAINAAKKFNVNTSIAVIVVGVFLHPNFSAWVSSGDPISFIGVPIQGVIYVASVIP
                     ALLTVWMMSYIEKFIDKLTPSMLKTILNPTLVLLISAPIALIVIGPIGNFLGEGLASI
                     INLLQGRLGFIMVCLLAAAMPFIVMTGMHHALTPIFISAFATTGQESLILISQVCANL
                     AQGGATLAVALRSKDSKMKQLASAAWISAIMGITEPALYGVTLKLKKPAMLASIGAGI
                     AGLFAGITHVTLYVPQNSIMAVLGLSGEKGISNIVNGLIVIFIALVAPFIMTYVFGVE
                     KNVK"
     gene            14118..14960
                     /locus_tag="PC494_002429"
     CDS             14118..14960
                     /locus_tag="PC494_002429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HDF3912924.1"
                     /translation="MIINKILNNNVVITLDDNDEEVIVMGKGIGYQKSKGNLIDKTKV
                     NKVFRISNKEISNKLQELLNNIPIEHMKLSSEIIEYAQIKLNKKLNESIYISLSDHTY
                     SAIQRMKEGINVKNAILWEIKRFYKEEFEIGMKALDIIENKTGIKLPEDEAGFIAFHI
                     VNAQLSEGHTLASDITKLIQEVLSIVRYHFRIEFHEESVFYYRFIMHLKFFAQRLLLD
                     SAHEGETDKELLSIIKSKYNKEFECVVKIKNFIKKQYNYILTDDELIYLTIHLAKVVK
                     DSNM"
     gene            15105..17033
                     /locus_tag="PC494_002430"
     CDS             15105..17033
                     /locus_tag="PC494_002430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HDF3912925.1"
                     /translation="MGKYKQLAQEIVNNVGGKENISGLVHCITRLRFTLKDESIANDN
                     VLKNMEGIVTVMKSGGQYQVVIGNHVEAVYKDVVEIIGLDDSSTSSETKKSGNILDKG
                     IDIISGIFQPVLGIMAACGMLKGFNALFVAMGLYSDVSGGYMVINAAGDALFTFLPLF
                     LGYTSAKKFGLKPMLGLALGAAVCYPAIQGSSISAGADVMYTLFKGTMFASPVYIDFF
                     GLPIVSIDYTGTVVPIIFIVYFASRCEKLFNKCVPNLVKFFFVPMLTLLITVPVALIV
                     IGPIATFGSTLISQIVISIRDFSPLLAGAIVGFTWQILVIFGMHWGFIPVYINNVMTL
                     GYDNVMMPFFACTFASSAVVLAIFFKTKDKKLKEMAIPNFISGIFGVTEPAIYGILLP
                     LKKPFIISCIASGIGGAFYGFFNLRKFITGGMGIFELPAMIEPDGGMGNLIVALSGIA
                     ISMVVAFVLTMILYKDEKVEESKKVRNKGKEEIKEVKSTKLEREIVTSPIKGEVLKLS
                     DIEDAAFASGVLGQGVAIIPSDGKVVAPVDGVVTTLFPSLHAIGILSDTGVEVLIHIG
                     LNTIQLEGRGFEACIKQGDRITKGQTILNFDVYAIKELGYSTVTPIVITNSSQFLDVV
                     ETESKNIELEDNLITVLF"
     gene            17094..18521
                     /gene="ascB"
                     /locus_tag="PC494_002431"
     CDS             17094..18521
                     /gene="ascB"
                     /locus_tag="PC494_002431"
                     /EC_number="3.2.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HDF3912926.1"
                     /translation="MSFKNDFLWGGATAANQCEGGYNEDERGLANVDVCPTGKDRTAV
                     ITGKLKMFDFDDEHYYPAKTGIDMYHNYKEDIKLFAEMGFKVYRMSIAWSRIFPKGDE
                     ETPNEKGLQFYENIFKECKKYKIEPLVTITHFDCPMHLVKKYGAWRNRKMIGFYEKLC
                     NVIFRRYKGLVKYWLTFNEINMILHAPFMGAGICFEEGEDVEKIKYQAAHHELVASAI
                     ATKIAHEVDSNNLIGCMFAAGSVYPYSCNPNDVWEATKLDRENYFFVDVQSKGKYPNY
                     ALKYMEQKGITPEMEPGDIELLNKYTVDFISFSYYNSRCVRTDENADDMAEGNIFTSA
                     KNPYLSYSQWGWPIDPLGLRITLNHVYDRYEKPLFIVENGLGAKDIADENGYVEDDYR
                     IDYLREHIKAMHDAVSIDGVDLLGYTTWAPIDLVSAGTGEMEKRYGFIYVDRDNSGNG
                     SLRRMKKKSFEWYKKVIASNGEDLY"
     gene            18968..19744
                     /locus_tag="PC494_002432"
     CDS             18968..19744
                     /locus_tag="PC494_002432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HDF3912927.1"
                     /translation="MKYQHIIEVDKELCIGCGLCKNDCPVNNIIIENKKSVIKKQDCL
                     MCGHCAAICPTKAITLTGFDEPPIELTNKPKLDSDELLMAIKSRRSIRKFKDKEVSSE
                     IIKQIIEAGRYTPSAKNSQDVSYIVLDNKKSIYENEAVKFFRKIKPIANIAIKYSKEV
                     EIDDNFFFKHAPIAIMIITKDKISGSLAASNMALMAESYGLGVLFSGYFSDVANNSPK
                     LKKLLGLKRSNHVLTTLVIGYPDVKYRRTAQKEVATVRYL"
     gene            19760..20125
                     /locus_tag="PC494_002433"
     CDS             19760..20125
                     /locus_tag="PC494_002433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HDF3912928.1"
                     /translation="MEKECQQRMQEITSKFKECRKAISAMGDETRQLILIALLESDFN
                     GIRVGEITKKTHLSRPAVSHHLKILKEAEIVNLRREGTKNYYYLDSKKSQWKSLTELI
                     NLIFVGIQHISENDIRKGD"
     gene            complement(20291..21040)
                     /locus_tag="PC494_002434"
     CDS             complement(20291..21040)
                     /locus_tag="PC494_002434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440038.1"
                     /note="N-terminal region resembles flavodoxins. C-terminal
                     ferrodoxin region binds two 4Fe-4S clusters; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EFR1 family ferrodoxin"
                     /protein_id="HDF3912929.1"
                     /translation="MILYFSGTGNSRYVARKIAQELNDELISLNQLIKEEKTDELISA
                     DKPFIFVCPTYAWRLPIVVTDFIKETKFLGSNRVYFVMTCGGDTAKSINYIQKLCKYK
                     EWQLKGMAEIKMPENYIALFSTTDKETSKQMIKEADKQIYRIISDIRNENEFETITPS
                     GLGGTIKSGIINTVFYKTIISAKGFHYTDKCIGCGKCVELCPLNNINLKNKKPVWKNN
                     CTHCMACICGCPTEAIEYKNKTQNRERYYLE"
     gene            21218..21370
                     /locus_tag="PC494_002435"
     CDS             21218..21370
                     /locus_tag="PC494_002435"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3912930.1"
                     /translation="MRRDNNLLMKDYKYKGYFKGVEIFDNVNDLNLNTLTTVSRFVLV
                     FLFTIT"
     gene            21498..21923
                     /locus_tag="PC494_002436"
     CDS             21498..21923
                     /locus_tag="PC494_002436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF3912931.1"
                     /translation="MINENLKSLRKINQYTQEELAEKLNVSRQSIAKWESGESIPDIC
                     SCIKLAKLYNVKLDDLVNHSEEKTGIIVPPKGKFFFGAVVVGERGQIVIPKEAREVFN
                     INAGDKLLVLGDEERGLGIVHQRDLINFIGHVGVVRKEE"
     gene            21955..23142
                     /locus_tag="PC494_002437"
     CDS             21955..23142
                     /locus_tag="PC494_002437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosyltransferase"
                     /protein_id="HDF3912932.1"
                     /translation="MSKIVFFSIPAYGHTNPTIEVVRELVDRGNEVLYYSFNEFKDKI
                     EGAGAKFICCDKYLPELLPGDEKKIGKDFPGLIEMIVDTTISLDEKVCRELKDFNPDC
                     IVSDSLSFWGKLFAQKLNIPYVCSTTTFAFNKHTAKLMKQNFIEIIRMIFGVRRINKK
                     IKLLQRKGYEVKNFISIVSNDNDTDTIVYTSKEFQPMVETFSSKYSFVGPSVSKLIIE
                     PKERKRKLIYISLGTINNKNVSFYKNCISAFKDSDVDVIMSVGRSTDIKSLGNIPNNF
                     EVKNSVEQIAILQKTDVFVTHSGMNSVNESLYYGVPMVLFPQHSEQRMVAKRVVHLGA
                     GIMLKEDKSESIKKAVFQVINDNEYKENATKLSKSFYNAGGSKKAADVILQIICNSRQ
                     VDI"
     gene            23334..23738
                     /locus_tag="PC494_002438"
     CDS             23334..23738
                     /locus_tag="PC494_002438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3139 domain-containing protein"
                     /protein_id="HDF3912933.1"
                     /translation="MKKYKVIFIVLIIGIISVTGFVVYKNCIKPWKDAETYIDKYMVK
                     QDISKDNIKSITKEKAKKASYEGILYKVYYKDDPRYEYQYFYSDNYYALYVNKVMLQI
                     YDMENNNKLLRSNEELKSVKYPPIYLKYKPDK"
BASE COUNT         9522 a         2463 c         4174 g         7662 t
ORIGIN      
        1 attaaggtca gattataatt gttttaagat aaaatgtaat aaaatttaat ggagaaattt
       61 tataggtaga taaattttaa tatttataag attatgttaa ggaaacactt aaaaattaga
      121 ttaaaattgt gggtatttaa atcaactaaa agatattgac tatttagtca atatcttttt
      181 ttattaaaaa ggaatataca tataaatagg ttagattaaa aattgggata aatatgattt
      241 atatagcatc atttaattaa aaggagctat attagtattc attcatacaa ttggataata
      301 tacaatgtca gccttgcttt atggtgtttg taataaatct atttcagttt ctattgtaat
      361 taatatgcaa gaatttaaga taggagtatc tatggcttat ggtgtattag taattggtat
      421 atgctatata gcattaggaa taatttttaa attagataga aaaagattta cataagataa
      481 caaaggctaa tttataaatt ggtgcttaga aaaccaaatc actttattag ctagagatga
      541 atttggaggg tgtcactttg gtgttttatg taaagtttat ggaagtaaaa cattagataa
      601 tcgtgagtaa gatttctata aatcgtatat actattggaa tccaagaaaa ggtattggcc
      661 aaatagctaa tatcttttta atttttttga ctctaatata gcattaacta ttgcatgagt
      721 atctttaaat ttatagttaa tgtatcttaa ttgtttatta taaaatctag gaaggctaaa
      781 gcataaaaca cttaaaaaga gaagatgtac atgagaaata taattaacta tgatgcagac
      841 ttctaaaaat tatttagtga aaaggaactt agagtgtata ataaaagttc cttttcacta
      901 aggaaaacga ttgttatttt ctgacattca ttaccctgat attatttaaa tataaacaac
      961 aacaaaatta acaagaagca aattcaacct aaaatttaaa atatcgggag gtacaatatg
     1021 ttaataaaca tgaaggaaat gctaaaagtg gcacaagaaa atcaatttgc tgtaccagca
     1081 tttaatatag gaagtgggca aatacttaaa gcagtagtac agagtgctaa cgaaaaaaat
     1141 gcaccagtaa tacttgcaat acacccaaat gagctaagtt ttctaggaga tagctttgta
     1201 gctagttgca tagaagaagc aaataagagt aaagtaccta tggtaataca cttagatcat
     1261 ggggaaaata aagaacaaat attaagggca ataagatgtg gatttacatc agtaatgatt
     1321 gatggctcac atttaccata tgaagagaat gtagctatat ctagggaaat agtagaaata
     1381 gcaaaaggat taaatgtgtc cgtagaagga gaacttggaa caataggaac aacaggaaca
     1441 tcaagtgaag gtggtactga tgaaataata tatacagatt caaaattagc taaggatttt
     1501 gttgaaaaaa caggagtaga aacactagct attgcaattg gtacagcaca tggtatatat
     1561 ccaaaaggtt ttaaaccaga gcttaaacta gatttattaa aagaaataag agaagtagta
     1621 gatatacctt tagttcttca tggtggttca tcaaatccag atgaagaaat agcacaagca
     1681 gttaaactag gagtttgtaa aataaatatt tcgagtgatg ttaagtcggc atattataag
     1741 aagtgcagag aactattaga acaaaaccca agcttatatg agccagatac tatatatcca
     1801 ccatgtataa aatctgcaag agaagttata gagtttaaaa tgaatctatt caatgctata
     1861 gataagttaa agtgctttta taaaaataaa aattaattat gaggtaacaa attaaaagga
     1921 ggggagaatt tatgataggt aaaatactac gaagcgattg tattgtacta gataaacaat
     1981 tacaaacaaa aaaagatgta attaattata tggcaaatca tttgtaccat ggaaattata
     2041 taaataataa agaaaagttt atagctgata ttaataaacg cgaaaaagaa tcatcaacta
     2101 atatgggtaa tttaatagct atacctcatg ctaagtcaaa tgtagtaaat caacctgtaa
     2161 tgatgtattt aagaacagat agagagatta cagataatga tggtcaaaaa cttaggtcat
     2221 tttttatgat agcagttcca gaatcaggtt cagatgaaca tcttaagatt atatctaaac
     2281 tagctacata tctaatggaa gaaaattttc ttaagcatct actaagtgca gaaactccat
     2341 acgaaatatt aagtatattt aataataaag ctgcagaatc aggagatttt agtaataatc
     2401 aaaataaagg tcttatagtt gggataacag gatgtccaac aggtatagct catactttta
     2461 tggcaaaaaa agcattagag gaagcaggtc aagaacttgg atatgaagtt aaaatagaaa
     2521 ctcatggagc tataggtgta gaaaataagt tgactaaaga agatataaaa agagctgaat
     2581 acgtaataat agcttgtgat aaagaagttc aactgagtag atttatagga aagaaagtgc
     2641 tacaaaagaa agtagtagat gctaagaatg tttcattagc taaaaattta attataaacg
     2701 ctgaaaatgg aatggctaaa gaaattaaac caggtggaaa gactttagaa gattcaaaag
     2761 aaatgcttca agggtcagag aaaaagggtg tttataagca cttaatgagt ggtgtatctg
     2821 aaatgattcc atttgtagtg ataggtggaa ttggtatagc catagctttt atgtttggta
     2881 tatttgcatc agacccaact catgaaacat acaaccctat agctggattc tttggacaac
     2941 ttggaggcga ttcagcattt aagttattta taccgatact tgctggtttt atagctaaat
     3001 caatagcagg aagacaagga tttgctcctg ctatgatagc tggttttatg gcagttattg
     3061 gaggttcagg ttttataggt ggtatggtag ctggttttgc aacaggatat atagctttag
     3121 gagtaatgaa gataacagaa aatttaccag atgtattaaa aggagtaaat gctgtattga
     3181 tatgtccact tttgattgca tttacgagtg gagctataat gttctttgta gttaatacgc
     3241 cagcatcatg gttaaatgaa gctttacaat cttggttaca aagtatgtct ggaactaata
     3301 aagtattatt aggtgcaata ttagcaggga tgatggcatc agatatggga ggacctatta
     3361 ataaaacagc ttcagctttt ggattggcta tgttttcaag taatatattt gaaccatcag
     3421 cagcattaat ggtaggagga atggtacctc cattagcaat atcattagct atgttaatat
     3481 tcaaaaataa gtttactaaa gaagaaagaa agtcatctct accaactgct ataatggggg
     3541 catctttcat aacagaaggc gcaataccgt ttgcagctgc agacccatta agaatgattc
     3601 cagcaaatat aattggttct tgtataggtg gggcaatatg tatgagttta gatataactt
     3661 taatggcacc acatggggga atatttgtaa taccatttgc atgtagtgca ccagttgcat
     3721 atatagcttg tatattgatt ggtacagtaa taacagcatt gattataggg gtaacaaagc
     3781 ctactataag gagtgaaaat agtgaagttg aattacttgg tgcttaaatt ataaataata
     3841 gtaaaaataa ttaatggaat aacaacaagt atatagaata ataataagga tatttagaat
     3901 cagttaacta cttctaaata tccttaattt ttattttgaa attatattat ctattatatc
     3961 aatttagtaa ggtgtatcat aaattctttt atgatacaga agtatcttag taattttaca
     4021 tagttagtaa atatgttaaa atagtactta atataaacat agaaatatat aaacataggt
     4081 agggagggct aagtatgctt gtgtcgaggc aaattgaatt tcttaaattg atactaaacg
     4141 aaaataaata tagacctata aaatacttta aagataaatt aaatgtatct gataaaactt
     4201 tacaaaaaga tttgaagatg attgagaaat atttagaaac ttttaatata aaaattgata
     4261 taaaaagagg ctatggaata ttaatagaag atttagcaaa gaagaatata gacttaatta
     4321 atagtttaaa tatacaatcg aaggaaaata aatctttatc agtagagcag agaagaatgg
     4381 agattttaaa gtatttatta ctaaattcaa ataatataac ttcaataaat cagttagcag
     4441 ataaatatta tgtaagtaaa acttctatag taaatgattt taaatatata gaggcatgga
     4501 taaaagaata caatttaaaa cttaataaaa ctttagaagg aactaagatt ataggtaaag
     4561 aagtggatat aaggaaatcg attgccaaaa tgatggatga tttattagat gaaaattatg
     4621 aacaacatga tatatctgag ttaacaagat tagattctgc tacatttagt gcattgataa
     4681 atttatttga tattgattct attatatttg tagaaactat aattacagaa ttagaataca
     4741 atttaggata tactataaat cagccctact atataaattt aattacccat atacttatat
     4801 gtttaaagag aatcgaagaa ggtaatcaaa tagaatctca ggaagaaaga gaaatttctg
     4861 tagataattt ggacgagtta gtatataaaa atgtcagtac acttatagat aaaatagaaa
     4921 atagatacag agtaaaaata acgaaagatg aaattatgta catatatatt tttttggtat
     4981 catctggatt tagtagcgaa aataatagta gttacaatga tgaatcagat agattaagtg
     5041 aaagtgaaaa agtttcatct ataatgatag agaatatgtc acgattttta aatataaatc
     5101 tcaaaaatga tgacttacta cagaaaagtc tagcatctca tgtaaggcct atgttaaaca
     5161 gattaagata tgatatccaa ataaaaaacc cgttgttagg agagatacaa gagcgatttt
     5221 cagatgtgct gggattatgt atgatgacta taaatattat gacagagtat gataatctga
     5281 agaatattag tatagatgaa gtttcgtatc ttgccacata ttttcaagcg gcaatagaaa
     5341 gaaatatgag tagtaaaaga gtaatagtag tttgtcatac aggatatgga acatctcagc
     5401 tccttgcagc cagattaaaa agagaatttc ctgaatggac tatagttgat atagttccta
     5461 tgcatcagtt gagtaagcga aatttagatg atgtagactt tgtaatatct actgtaaact
     5521 tagatttgaa agataaatta catatagttg tatcagtact attaatggaa aatgatatta
     5581 ataatataaa aaatgcttta ctttctaaac ctaaaaaaag tatgaactta gatacaaact
     5641 tattaggaat gtatttagaa gataatatat attttaattt tgatgtagct cagatggaaa
     5701 gtttaatagg tgtgaattta gggagtaaat atgaatctat ttcattagga aaagatttaa
     5761 atatatatat acataagcaa agtaaattaa ataaagggat aatgaatatc aataatgtta
     5821 ctagaacgat tgatatttat ttagaaatta gtaatcaaag ttttttaaag aatattttaa
     5881 tggaaatatc aaatttatat aggcaaaaga actatataaa ctatataata gattgcaaga
     5941 gcaaagagga tattaaaata ttatttaaga ataatctatt ggagaaaaca aatggaaatt
     6001 agagaaatat taacagaaga aagcattatt ttagatttga aatcaactac aaaagaaggc
     6061 ataatacagg aattagtaga taaattatac gatacaggaa gtataacttt aaaaagtaag
     6121 tttataaagg cattaaaaca tagagaaaaa ataggctcta ctagcatagg ttatcaaatg
     6181 gccatgccac atggaaaaac aaaatatgta aagaaggcat ccatagtaat aggtaaatct
     6241 aaaaaaggtg tagattggcc aagtatagat ggcttacctg taaaggtaat aattatgttt
     6301 gctatgccac aatctggagg caatgaagat atgatattaa tatctaaaat agcttacatt
     6361 ttaggtggta aaaatatagg tgaaagactt ttaaatgcaa atacaaaaaa agaaatatta
     6421 gatatatttt atgaagtgta ggtattgtat aaattataaa tttgaggttt ttaaaataaa
     6481 atgtgtattc ttttaaatag tataaattaa tttttagaca ctagagagga gaggatatat
     6541 atggcaatat atttagaaat gcctaaatta atacatgaat ttccttttcg tagtctatca
     6601 aatgaaggag aagtattaac aacaccacac tggcataagg aaatagaaat attacttata
     6661 acagaaggtg tagtaaatct atttataaat gacaagccta tgcaattaaa aaaaggcgag
     6721 atagtgataa taaaaggagg agatattcat tatatactgc catcaccggg aagtgaaaga
     6781 ttagtatttc aatttgatat atcttttttt aatgatttaa ttttattaaa tgaggaaaaa
     6841 gaaagcttaa ttaatttatt cagtagtata aaaaaatgta gtagagattg gtcagcaaaa
     6901 ataagaaagt cagttttcga tatattgata gatatctaca atgaagacct atacaaaata
     6961 gaaggatata gttatgcaat aaaaggtaaa atgtataatt taattcctat attatataga
     7021 cagattccta gagaaattga agaaaataca gtagaatatg aaataaactc taaagagata
     7081 ttagagagat tgaacaatat attcaaatat gtagaaaaaa attataaaca acctataaaa
     7141 ttagaagatg tgtcttatga agtaggattt agtgtatatt attttactaa atttttcaaa
     7201 aaaaatacag gaaaaacatt tataactttt ttaaatgaat atagattaga aaaagcaaag
     7261 tggatattac ttaataacaa tatatccatt gtagatttgg ttgaagaagt tggttttgga
     7321 agtacaaaaa ctttttacag agtatttaaa gaaaaaattg gagtctctcc attagaattt
     7381 aaaaaaagat ataatagctt ggaaaaaaaa gggagtgtct caaaatgaac ttagttcatg
     7441 aggcactttc ttttatatga aatcaaatat attttcagta tttcaacaat gaaaattcca
     7501 ttcatttata aagtctaaat tttagttctc aatacaacct ctatttcgaa ataaatcctt
     7561 ttatatataa atatacagca atatatgaga ataagataac aataatgagg atataaaaat
     7621 gtatttgcta tatatataat tatatacata gatatctaat attgatattt aatatgaaag
     7681 tattgaaaat agacaatatt aattatagtg agtaaaaaat ataattggat ttttaaattg
     7741 aattatttaa aaggtatagt atgaaaaaaa tcttataact aaatatgaga tagaaattat
     7801 aaaactttat attgtgaaag aggtagatgc atgaaattag ggaaagattt tttatgggga
     7861 ggggcaattt cagccaatca aagtgaagga ttttatttag atggaggaaa aggtttatct
     7921 cagtttgata aactcccatt aaatgataag agattaaaag atgtatgttt agatgaggat
     7981 aatattttaa atgaaaataa tcaatactat ccaagtcata tagggattaa attttgtgaa
     8041 aattacaaag aagatatagc aatgttagca gaaataggtt ttaaatgttt tagattttct
     8101 atatcttggt caagaatatt cccaacagga gaagaaagtg aaccaaatga aaagggatta
     8161 caactttatg ataatataat aaaagaatta aaaaaatata atatagagcc attaataacg
     8221 ataagccact ttgatatacc ttattctcta gttgaaaaat attctgggtg ggctgataga
     8281 agagtggtta atttatatgt aaaatatgct gaaattttga tgaaaagata taaagatgat
     8341 gtcaaatact ggattccttt taacgaaatg aatatgataa tgcatattcc atatataggt
     8401 gctgggttaa cttttatagc tgatgaaaat caacttcaga aaaaatatca agcagcacac
     8461 catcaattat tagctaatgc aaaaactata gaaataggaa ggtatataaa taaagaattt
     8521 aagtttgggt gtatgttagc tgctggaaaa acatatccat acacatgtaa accagaagat
     8581 gtatttgcaa ctttagagca tgaaaggtat aatttgtttt tttctgatgt tcaagttagg
     8641 ggtgtgtatc caagctttat gaattattat ttaaaatcaa atcaaataaa attaataata
     8701 aaagaggaag atttatcaac acttaaggat aatactgtag attttgtatc ttttagctat
     8761 tattctagtg cttgtagttc agctagagct gaaggtttag aaaaatcaaa ggcaaacgga
     8821 ccagaaacca taaaaaatcc atatcttcca aaatcaaata gtgtatggca aaacgaccct
     8881 gtagggttaa gaataactat gaatcagtta tatgaaaggt atcagttacc tttatttata
     8941 gtagaaaatg gactgggtac tcaagatatt gtgaatgaag atggaaaaat aattgatgat
     9001 tatcgtatag attacatgaa agaacatatt aaaaatatga ttcttggagt aaatgaagat
     9061 ggaatagagc ttataggata tcttatgtgg ggatgtatag atgtaaccag tgtaagtgaa
     9121 ggaaagatga caaaacgata tggcataatt catgttgatt ctgatgacta tggaagaggc
     9181 tcatttaaaa gaactaaaaa acaaagtgct ttttggtata aaaaagtaat agaaacagat
     9241 ggagaaattt tatttaatga catggaaact catgcataat tcattttaag aaaggagtgt
     9301 tattatgagt ttaatattta ctactaagga ccaacttata gagcaagggt ttagtaagga
     9361 tacaataaaa tccaatgaaa cgctgtttac actagctaat ggacatttag gagttagagg
     9421 gaatattgaa gagtctgatt ttaataatga gtatgtagat aatatgggta catatgtaaa
     9481 tggattttat gaagaatctc caattacata tggagaaagc gcttatggct atgcaaaaca
     9541 aaatcagact atctgtaagt tacctaatgc tcatatagta aatttctcta ttgaaggaga
     9601 ttattttgat ttatcaaaag gtattacaag tgaacattct aggatactag atttaaatga
     9661 agggattctt aaacgttcat ttatatggga aaactcttgt ggtagaaaag ttaaagtatc
     9721 tatagaaaga ttagtatcac aagatataga agaattaatg atgatttcat atacaataac
     9781 accattgaat tttaatggaa aaataaaatt taaaaataaa atggaaaata gtatggagaa
     9841 gtttaattgt gaaaaagtag atgacccaag agtggcatct ataaataaga agcaatttaa
     9901 aattaatgta aaaaaatata acaataagta ttttatgaat ttagttacag aaagaagtag
     9961 attagggtta tggtgtgggt ttgattcata tattacttgt ggaaatatta caaatgagac
    10021 ctataatgtt tcagatgaat gtattgagcg agaaatagaa gtctatgcca aaaaagatga
    10081 aaggttaaat ttagaaattg ttgtaggcta tagtagagta tattctgatt taaatctaaa
    10141 tgaagaacgt ttaaaatcat tagaatgtct ggagtcgtta aaatgtttag aatcagaagc
    10201 acatttaaaa tcattagaat tggttttaag agaagcatgt aatattggat ttgataaagt
    10261 caaaaatatt cagagaaaga aaatgaatga gttttggaca acctctgatg tagagattga
    10321 aggcgataaa actcttcaac tggggataaa aaccaattta tttcatattt atcaatcagc
    10381 aggaagagat ggaaagacta atatatcagc aaaaggtctt acaggtgatg gctatgaggg
    10441 gcattatttc tgggatacag aaatgtatat attaccattt tttatatata ctcaaccatc
    10501 cattgctaga gctttattag attatagata ctcaatctta gatgcatcaa gagaaagagc
    10561 tagagaactt ggaataaata aaggttgctt atattcatgg agaactataa atggtaatga
    10621 atgcagtgca tattatccaa caggaacagc acagtttcat ataaatgcag atatagctta
    10681 tggtattaga acgtattttg aagcaactaa tgatgaagaa tttatgatgc aaaatggctt
    10741 agaaattctt atagaaacag caagattttg ggttgaattt ggagattata tagaatcaaa
    10801 aaataataaa ttctgtataa atggagtaac aggaccagat gaatatacag caatagtaaa
    10861 caataattac tacactaatt taatggctaa gtataattta atatatgcag tacagatggt
    10921 agataaattt aagcataatt tattttcaaa tgaagtattt agaaaagtta aattacaaga
    10981 atatgaagtg aaaaactgga taaatgccgc tcaaaatatg tatttaccat atgatgaaga
    11041 gaagaaaata agcaaacaag acgattcatt tttagaaaaa tcagtatggg attttaaaaa
    11101 tacaccaaaa gaaaaatatc cattacttct ccattatcat ccattaacaa tatatagata
    11161 tcaagtaaat aaacaagcag atactgtact ttcagcgttg cttttccctg atgagtttag
    11221 cttagaacaa aagaagagag attttgaata ctatgaaaaa ataactactc atgattcatc
    11281 tttgtcaagg tcaatatttg gaatgatggc aagtgaaatt ggaaatcatg aaaaagctta
    11341 taactatttt atggacacag cattaatgga tattaataac ctacaaaaaa atacaagtga
    11401 tggaatacat gctgctaata tgggtggaac atggatgagt ttagtatatg gatttgcagg
    11461 aatgaaaata aaaaatgata aattaagttt tgaaccaagg atacctaaac actggaaaaa
    11521 tattaaattt aatatattat ttagagataa tttagtttct gtaaatatag aagaatataa
    11581 atcttattat aagttaatca aaggtagaaa tataaccata ttacatgata ataaagaaat
    11641 aaaattatca aagaacataa tagaagttaa taattgtttt aaagggagta attaatatga
    11701 aagcagtctt atttgatctt gatggagtta taacagatac tgctaagtat cattttgaag
    11761 cttggcatga gatagcaaaa tcgctagata tagaaataga tgaaactttt aatgaaaaat
    11821 taaaaggcat aagcagggaa gaatcattag ataaaatatt gttatctgct aataaagtag
    11881 atagttatac taaagaggaa aagttaaagg tgtgtgaaga aaaaaataac atttatataa
    11941 agttaataaa ctcattaaca tataaagata tattaccagg gataaatgag cttataaaag
    12001 aacttaaaaa aaataatgtg aaattgggaa tagcatctgc tagtaagaat gcacctagga
    12061 tattagaatc tttgggaata aaagatgaat ttgattgtat agtaaatcca tctttattaa
    12121 aaaggggaaa accatatcct gatattttta ttgaagggag caagattcta aatttaaaac
    12181 aatatgattg tgtaggaata gaagattctt attcaggtat taaagctata aatgctgcta
    12241 atatgacatc aattggtgtg gggaaaaaag aagtactagg aaaatgtgac catattgtag
    12301 aagatactag cttattaaat tgcaatacac tattacaagc ttggagtaaa aagattaatt
    12361 tggattaaaa ttatattaaa aattatttta aaagagagga taaggtatga agaataaata
    12421 tgaagaagta gctcaattga taattgatgg ccttggagga aaggataata taattgactt
    12481 aactcattgt atgacacgat taaggttcat cttaaaagat gaaaagaaag tcaatgcaga
    12541 taaattaaaa tctatagata aggtagttgg agtaaactca acttcaactc aatatcaggt
    12601 tataataggt aatgaggtag gtgttgtatt taatgcaata ataaataagg ggataaatac
    12661 cacaggagat attaaaagcg atataaaaaa taaaaaaaat agtattttaa ataatataat
    12721 agatacaata actggttgta tgacacctat gataccagcc cttacagcat ctgggatgat
    12781 aaaagttata ttatctcttt gcaccacttt taattggcta tcatcaaatt caagtacata
    12841 tagagtatta gatataatag gagatgtagc attttacttt atgcctataa tacttgcaat
    12901 aaatgcagct aaaaaattta atgttaatac atcaatagca gttatagtag taggtgtgtt
    12961 tttacatcca aatttctctg catgggtatc aagtggggac cctatatcat ttataggagt
    13021 accaattcaa ggtgttatat atgtagcatc tgttatccct gcacttttaa cagtatggat
    13081 gatgtcatat atagaaaaat tcattgataa attaacacct agcatgttaa aaacaatttt
    13141 aaatccaact ttagtattat taataagtgc gccaatagca ttaatagtaa ttggaccaat
    13201 aggaaatttc ttaggagagg gattagctag tataataaat ttactacaag gaaggttagg
    13261 atttataatg gtttgtttat tagcagctgc aatgccattt atcgttatga cagggatgca
    13321 tcatgcattg actcctatat tcatatcagc atttgcaact acaggacaag aatcgctaat
    13381 attaatatct caagtttgtg ctaatttagc gcaaggtggc gcaacattag ctgtagcatt
    13441 aagaagcaaa gatagtaaga tgaaacagtt agcatcagct gcatggatat cagctatcat
    13501 gggtataact gaaccagctc tttatggagt tacattgaaa cttaaaaaac ctgctatgtt
    13561 agcatctata ggagcaggaa tcgcagggtt atttgcagga attactcatg tgactttata
    13621 tgttccacaa aatagtataa tggcagtact tggattatca ggggaaaagg ggatttcaaa
    13681 tatagtaaat ggacttatag ttatatttat agcattggtt gctccattta ttatgacata
    13741 tgtttttgga gttgaaaaaa atgttaaata aagtacagat aatgtagtag aggaagtata
    13801 atattaacta tttacattaa tagaattttt attattattg actataactt gttttgtatt
    13861 tatattgatg caaagaaata agttaatatt aataagaata attattagaa ctgacaaaaa
    13921 gcaacataaa agattgatga agtatatgga aataaaaagt tgacaaaata tgtctgatgt
    13981 tttatcatat taattggaat taggtagtaa ttgtttaagt acaagctaag cttattcatt
    14041 aataatagca gtatcctagg aaggagtatg cccattatta tggataagct ttttttatgc
    14101 ttaaaaggag gataatcatg ataattaata agatattaaa caataatgtt gtaatcacat
    14161 tagatgataa tgatgaagaa gttatcgtta tgggtaaagg aattggttat caaaaatcaa
    14221 aaggcaatct aatagataaa actaaagtaa ataaagtatt tagaatatca aataaagaaa
    14281 tatcaaacaa actacaagaa ttactcaata atattcctat agaacacatg aaattatcaa
    14341 gtgaaattat agaatacgca caaataaagt taaacaagaa gctaaatgaa agtatttaca
    14401 tatccttaag tgaccataca tattctgcaa ttcaaaggat gaaagaagga ataaatgtaa
    14461 aaaatgcaat cctttgggaa attaaaagat tttataaaga agagtttgaa attggaatga
    14521 aagcactaga tattattgaa aacaaaacag gtataaaatt accagaagat gaggctggat
    14581 ttatagcctt tcatatagtg aatgctcagt taagtgaagg tcatactttg gcatctgata
    14641 ttacgaagtt aatacaagaa gtacttagca tagttaggta tcattttagg atagaatttc
    14701 atgaagaatc agtgttttat tatagattta taatgcattt aaagtttttt gcgcaaagat
    14761 tgcttttaga tagtgcacat gaaggtgaga cagacaaaga attactaagc attattaaat
    14821 ctaaatataa taaagagttt gaatgtgtag ttaaaattaa aaatttcatt aaaaaacaat
    14881 ataactacat attaacagat gatgagctta tatatttaac aatacattta gctaaagtag
    14941 ttaaagactc aaatatgtaa gtgaaataat ttttcagtag tatattaaga atgattgaaa
    15001 ggagtgatac taacaaaatt atacttatgg ttggatggta acattgagtt ggccaaacct
    15061 tcaaatttca aaaaattaat ttaaacgaaa tatggaggag aaaaatggga aaatacaaac
    15121 aattagcaca agagatagta aacaatgttg gtggaaaaga aaatattagt gggttagtac
    15181 actgtattac aagattacgt tttactttaa aagatgaaag tatagcaaat gacaatgtat
    15241 taaaaaacat ggaaggtatt gttactgtaa tgaaaagtgg aggacaatat caagtagtta
    15301 taggaaatca tgttgaagct gtctataaag atgtagttga aataattggt ttagatgatt
    15361 caagtacaag ttcagaaact aaaaaatcag gtaatatact agataaaggt atagatataa
    15421 tatcaggaat ttttcagcca gtgttaggaa taatggcagc ttgtggtatg ttgaaaggat
    15481 ttaatgcatt atttgtagca atgggattat atagtgatgt atctggtggt tatatggtaa
    15541 taaatgcagc aggagatgca ttatttacat tccttccttt gttcttagga tatacttcag
    15601 ctaagaagtt tggattaaaa ccaatgttgg gattagcact aggagctgca gtatgttatc
    15661 ctgctataca aggtagcagt atatcagcag gagcagatgt gatgtacact ttatttaaag
    15721 gaacaatgtt tgcatcacca gtatatattg atttctttgg actaccaatt gtatcaattg
    15781 attatactgg aacagtcgta ccaattatat ttatagtgta ttttgcttct aggtgtgaaa
    15841 aattatttaa taagtgtgtt ccaaatttag ttaagttttt ctttgtgcca atgcttacat
    15901 tattaataac agtgcctgtt gcacttatag ttataggccc tatagcaaca tttggttcta
    15961 cacttatttc acaaattgta atttcaataa gagattttag tccactattg gcaggtgcta
    16021 tagtaggatt tacttggcaa attcttgtta tttttggtat gcactgggga tttattcctg
    16081 tatatataaa caatgttatg actttaggat atgataatgt tatgatgcca ttctttgcct
    16141 gtacatttgc aagttcggca gttgtgttgg caatattttt caagactaaa gataaaaaac
    16201 taaaagagat ggcaatacca aactttatat ctggtatatt tggagttaca gagccagcaa
    16261 tttatggaat attattgcct ttaaagaaac catttataat aagttgtatt gctagtggta
    16321 ttggaggcgc tttctatgga ttctttaatc ttagaaaatt tataactgga ggaatgggaa
    16381 tatttgaact tccagcaatg attgaaccag atgggggaat gggtaactta atagtagctc
    16441 tttctggtat agctatatca atggtcgtag cttttgtatt aactatgatt ttatataaag
    16501 atgagaaagt agaagagtct aaaaaagtaa gaaataaggg taaagaagaa ataaaagaag
    16561 tcaagtctac taaattagaa agagaaatag taacaagtcc tataaaaggt gaagtattaa
    16621 aattaagtga tatagaggat gcagcatttg catctggtgt actaggtcaa ggggtggcaa
    16681 taatacctag tgatggaaaa gtagttgctc cagtagatgg ggtagttaca accttatttc
    16741 ctagtctaca tgctataggg attctttctg atacaggtgt tgaagtgctt attcatattg
    16801 gattaaatac tattcaatta gagggaagag gttttgaggc atgtataaaa caaggtgata
    16861 gaattacaaa aggtcaaact atattaaact ttgatgttta tgcaataaaa gagttggggt
    16921 atagtactgt aactccaatt gttattacaa attcatcaca atttttagat gtagtagaaa
    16981 cagaaagtaa aaatattgaa ttagaagaca atctaattac agtcttattt tagtaaagat
    17041 tgaggtatta gcataatcta gtgctttggt tataatttta ggaggctttg actatgagtt
    17101 ttaagaatga ttttttatgg ggaggagcta ctgcggccaa tcaatgtgaa ggtggataca
    17161 atgaagacga aagaggattg gcaaatgtag atgtatgtcc aacaggaaaa gatagaacag
    17221 cagttattac agggaaacta aaaatgtttg attttgatga tgagcattat tatccagcta
    17281 aaactggtat tgatatgtat cataattata aagaagatat aaagttattt gctgaaatgg
    17341 gatttaaagt atatagaatg agcattgcat ggagtcgaat atttccaaaa ggtgatgaag
    17401 aaacaccaaa tgaaaaggga cttcaatttt atgaaaatat atttaaggag tgtaaaaaat
    17461 ataaaataga gcctttagtc actattacac actttgattg tccaatgcat ttagttaaaa
    17521 agtatggtgc atggcgtaat cgaaaaatga taggtttcta tgagaaatta tgcaatgtta
    17581 tctttagaag atataaagga ttagtgaagt actggctaac tttcaatgaa ataaatatga
    17641 ttttacatgc tccatttatg ggtgctggta tttgctttga agaaggtgaa gatgttgaaa
    17701 agataaaata tcaagctgcc catcatgagc ttgtagctag tgcaattgca actaaaatag
    17761 cacatgaagt tgattcaaat aacttaattg gatgtatgtt tgcagctgga agtgtatatc
    17821 cttatagttg taatcctaat gatgtatggg aagctacaaa gttagataga gaaaattact
    17881 tctttgtgga tgtacaatct aaaggtaaat atcctaacta tgcgttaaag tatatggagc
    17941 aaaaaggtat tacaccagaa atggaacctg gtgatattga attattgaat aaatatacag
    18001 tagattttat ttcattttca tattacaata gccgttgtgt tagaaccgat gaaaatgcag
    18061 atgatatggc tgaaggaaac atatttacat ctgctaaaaa tccatatctt tcatacagtc
    18121 aatggggatg gccaattgac ccattaggtt tgagaattac actaaatcat gtatatgata
    18181 gatatgaaaa gccactattt attgtagaaa atggattagg tgctaaagat atagctgatg
    18241 aaaatggtta tgtagaagat gattacagaa ttgattatct aagagaacat ataaaagcta
    18301 tgcatgatgc agtttctata gatggggtcg atttattagg ttatactaca tgggcaccta
    18361 ttgatttagt aagtgctggt acaggtgaaa tggaaaagcg ttatggattt atatatgtag
    18421 atagagacaa tagtggtaat ggaagtctaa gaagaatgaa aaagaaaagt tttgaatggt
    18481 ataagaaagt aattgcttca aatggtgaag atttatatta gacaagaaat ctatgttaaa
    18541 taagaaatct atattagaca agaaatctat gttaaataag aactttgtat taaataagaa
    18601 gagtataaaa attaataata agtataattt ttaacttttt taactataga aaatcaatat
    18661 agaattattt tacattgtat tgatgcaata gtatgattca caaataaaat tttagaaaat
    18721 aaaattgtta agaagtatgg gaagtaagtg caatttactt tgtaataaaa gatgaaaaag
    18781 gcaagcttag gttttaagct tgtctttttt attatgtata aactatgata ttttaaaatt
    18841 ctatgaaaaa tttatttaat agagaaatta aaaatttaat ggtaatcaaa ttctttacca
    18901 atgaatataa aaaatgtcta cgtgttataa tagtttaaac taataaacga aaggtagatg
    18961 aatgaatatg aaataccaac atataataga agttgacaaa gaactttgca ttggatgtgg
    19021 gctttgtaaa aatgattgtc cagtaaacaa tataattata gaaaataaaa agtcagtaat
    19081 taaaaaacaa gattgtctaa tgtgtggaca ttgtgcagca atatgtccca caaaagctat
    19141 taccttgaca ggatttgatg aacctcctat agaacttaca aataagccaa agctagattc
    19201 agatgaatta ctaatggcaa ttaaatctag aagaagtata cgtaaattta aagataaaga
    19261 agtttcttca gaaattataa agcaaattat tgaggcaggt aggtataccc ctagtgctaa
    19321 aaattcacaa gatgtatcat atattgtttt agacaataaa aagtcaattt atgaaaacga
    19381 agcagtgaaa ttttttagaa aaataaaacc tattgcaaat atagctatta aatattcaaa
    19441 agaagttgag attgacgata actttttctt taagcatgct cctattgcaa taatgataat
    19501 tacaaaagat aagattagtg gttcacttgc agcatcaaat atggcattaa tggcagagtc
    19561 ttatggtcta ggtgttttat ttagtggata tttttcagat gtagcaaata attcgccaaa
    19621 attaaaaaag cttttaggtc taaaacgtag taatcatgtt cttacaacat tagtaattgg
    19681 atacccagat gttaaatata gacgtactgc acagaaagaa gtagcaactg ttagatactt
    19741 ataagagagg gtggatttta tggaaaaaga atgtcaacaa agaatgcaag aaataacgtc
    19801 taaatttaaa gaatgtcgca aagctatctc tgctatgggt gatgagacta gacaattgat
    19861 tttaattgct cttttagaga gtgattttaa tggtatacga gtgggagaaa tcacaaaaaa
    19921 aacacatctt tctcgtcctg ctgtatctca tcatcttaag atattaaaag aagcagagat
    19981 tgttaatttg cgtagagaag gaacgaaaaa ttattattat cttgattcaa aaaaatcaca
    20041 atggaagtca ctaacagagc taataaatct tatatttgtt ggaatacaac atattagtga
    20101 aaatgatata agaaaaggtg attaaattat acttgattta atacaaaaag attgatttag
    20161 gaactaaaaa attcactttg agacactatc ttttgaacta tacccatttt aggagacggt
    20221 taaaatatgt aaaactgtat aaaacaatgg gtatagttca ttttataatg gtttaaatat
    20281 taagaatata ttattctaaa tagtatcttt ctctgttttg agttttattt ttatactcaa
    20341 tagcttcagt ggggcaacca caaatacatg ccatacaatg agtacagtta tttttccaaa
    20401 ctggtttttt gttttttaaa ttaatattat ttaaaggaca tagctctaca cattttccac
    20461 agccaatgca tttatcagta taatgaaatc ctttggcact aataattgtc ttataaaaaa
    20521 ctgtatttat tataccactt ttaattgtac ctcctaagcc actaggagta atagtttcaa
    20581 attcattttc attgcgtata tcagaaataa tcctatatat ttgtttatct gcttctttaa
    20641 tcatttgttt tgatgtttct ttgtctgttg tagaaaataa agctatataa ttctctggca
    20701 ttttaatttc tgccatacct tttaattgcc attccttgta tttacatagt ttttgaatat
    20761 agtttatgga ttttgctgta tctccaccac aagtcattac aaagtaaact ctgttgcttc
    20821 ctagaaattt tgtttctttt ataaaatccg taactactat tggcaatctc catgcataag
    20881 taggacatac aaatatgaat ggtttatctg ctgatattaa ttcatctgtt ttttcctctt
    20941 ttataagttg atttagtgat atcagttcat catttaattc ttgtgcaatt ttacgagcca
    21001 catatcggct attaccagtt ccgctaaaat ataaaatcat aataatatct ccctaactat
    21061 tttttattta ttatagtaat ttattgatat attctattca aatgtatgta aaatttagta
    21121 gttaagaaaa ttataacaca ttagtaattt ttatacttat tggtaaagaa tttgattacc
    21181 attaaattta gcaacaagac atcaactgga cttgtatatg agaagggata ataatttgct
    21241 tatgaaagat tataaatata aaggttattt taaaggtgta gaaatatttg ataatgtaaa
    21301 tgaccttaac ttaaatactt taacaacagt tagtagattt gtgcttgttt ttttgtttac
    21361 gataacttaa ggaaatatgt tacctgaata ataaatttat ataataaaag tatataaata
    21421 tatatatgaa tgttaagatt agttgataga atttaaataa taaatccaat attataaaca
    21481 taggaggtat gaaaaatatg attaatgaga atttaaaaag tctaagaaaa atcaaccagt
    21541 atacacaaga agaattagct gaaaaactta atgtttctag acaatcaata gcaaaatggg
    21601 aaagtggaga atctattcct gatatatgta gttgcattaa acttgcaaaa ttgtacaatg
    21661 tcaaactaga tgacttagtt aatcattcag aagaaaaaac aggtattata gtacctccta
    21721 aaggaaagtt tttctttgga gcagttgtag ttggtgaacg tggtcagatt gtcattccaa
    21781 aagaagcaag agaagtattt aatataaatg caggagataa attattggta cttggagatg
    21841 aggaaagagg attaggaatt gttcatcaac gtgatttgat aaattttata ggtcatgtgg
    21901 gagtagtacg taaagaagaa tgatttaaaa aaattataaa aggaggtatg aaatatgagt
    21961 aaaatagtat tttttagcat tcctgcatat ggtcatacta atcctactat tgaagtagtt
    22021 cgtgaattag tggatagagg aaatgaggta ttgtattatt cttttaatga atttaaagat
    22081 aaaattgaag gtgctggagc aaaatttatt tgttgtgata aataccttcc agaattactc
    22141 cctggagatg agaaaaaaat tggtaaggat tttcctggat taattgagat gatagtagat
    22201 actactattt ctttagatga aaaagtttgt agagaactta aagattttaa tccagattgc
    22261 attgtatcag attcattaag tttttgggga aagttatttg cacaaaaact taatattcca
    22321 tatgtatgct ctacaacaac ttttgcattt aataaacata cagcaaagtt gatgaaacaa
    22381 aactttatag aaattatacg tatgattttt ggtgtaagac gcattaataa aaaaataaag
    22441 cttttacaaa gaaaagggta tgaagtaaaa aattttattt ctatagtttc taatgataat
    22501 gatacggata ccattgtata tacatcaaaa gaatttcaac caatggtaga aaccttctct
    22561 agtaagtatt catttgtagg tccatcagta tcaaagttga ttattgaacc taaagagaga
    22621 aaaagaaagc taatatatat ttcgcttggt acaattaata ataaaaatgt tagcttttat
    22681 aaaaactgta taagtgcatt taaagattct gatgttgatg tgattatgtc tgttggtaga
    22741 agtactgata ttaaaagttt aggaaatata ccaaataatt ttgaggtcaa aaatagtgtt
    22801 gaacagattg ctatacttca aaaaactgat gtgtttgtta ctcattctgg gatgaatagt
    22861 gttaatgaaa gtttatatta tggagtacct atggtattat ttcctcaaca ttcggagcag
    22921 agaatggtag ctaagagagt tgttcatttg ggagcaggaa ttatgttaaa agaggataag
    22981 tcagaaagta ttaaaaaagc agtatttcaa gttataaatg acaatgaata taaagaaaat
    23041 gcaactaaac tatcaaaaag cttttataat gcaggaggct caaaaaaagc agcagatgta
    23101 atattacaga ttatatgtaa tagtagacaa gttgacatat aatagatttg ttaaaaatat
    23161 atatacatac atgtaattta atcaaagtac tgacagtggg gtcttttaac ctaccagttg
    23221 gggcatatat attgatgcta aatatgaggg atgttatatt ttaataaaaa agataacatc
    23281 ctttttttag tgcattatat cgagttttaa ataataaatg aaggaggatc aatatgaaaa
    23341 aatataaagt tatttttata gtattaatta taggtattat aagtgtaaca gggtttgttg
    23401 tatataaaaa ctgcattaaa ccatggaaag atgctgaaac atatattgat aagtatatgg
    23461 taaaacaaga tatttcaaaa gataatataa aaagtattac aaaagaaaaa gccaagaagg
    23521 caagttacga aggaatacta tacaaagtgt attacaaaga tgaccctcga tatgagtatc
    23581 aatattttta tagtgataat tattatgctc tatatgtaaa taaagtaatg ttacaaattt
    23641 atgatatgga aaataataat aaacttttaa gaagtaatga ggaattaaaa agtgtaaagt
    23701 atccaccaat atatcttaaa tataagccag ataaatgatt tatgacaaaa tagaatgatt
    23761 tttattaaaa tttatttaaa aatatcacta gagcgtttaa ataaaactaa atttaagtat
    23821 t
//
LOCUS       DAMKNB010000055        23438 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.057, whole genome shotgun sequence.
ACCESSION   DAMKNB010000055 DAMKNB010000000
VERSION     DAMKNB010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 23438)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23438)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23438
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.057"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            135..2153
                     /locus_tag="PC494_002439"
     CDS             135..2153
                     /locus_tag="PC494_002439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HDF3912934.1"
                     /translation="MRRNTKLLTTGILSMAIVAPTMAFATESNAMENNADLNINLEKK
                     SIVLGSTSKVSVKFKEKPDADSITLKYKCYDMPLDTTLNYNQSTESYEGTINYNKDPE
                     YLNVWELQGITINSKNNPKTLNKQELEKMGLNLKDYNVTQECIIEDITSRKDVNKYLR
                     KTSAPITELTGSDRYETAVKISKEGWKNGSDKVVIINGDVSIDGIISTPLATTYNAPI
                     LLVEKNNVPNSVKSELKRLNPRDVIIIGDENAISKTTANQIKSTVNASQTRLKGSNRY
                     ETSLLIAKEIDKNHDVEKVYITNANGGEVDALTIAAKAGQDKQPIILTDKNSITDNTY
                     KWLKSEDLQNAYFIGGPQMISTNVINKVNDITKDNVTNNRVYGADRHETNANVIKKFY
                     TDDELEAVLVAKSDVLVDALAAGPLAANLKSPILITPKTYVSAYHKENLEAKSANKVY
                     KIGGGLTSKVMSSIASSLSKHNTTPTEPGNSGGKTVMIDPGHGGSDTGTTGKPLGGIR
                     EKDYTLNTSLATTEYLRSKGFNVIMTRDTDKTLSLGNRTALSNSLRPDLFTSIHYNAS
                     DTTGNGVEVFYKLKDKDGGTTKTVATNILNRILEKFNLKNRGAKTRTLSTDPTKDYLY
                     VLRNNDMPAVLVECAFLDNEKDMSLLNTSNKVKEMGTQIGKGIEDSLK"
     gene            2658..4670
                     /locus_tag="PC494_002440"
     CDS             2658..4670
                     /locus_tag="PC494_002440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HDF3912935.1"
                     /translation="MRRNTKLLTTGILSMAIVAPTMAFATESNAMENNADLNINLEKK
                     SIVLGSKSKVSVKFKEKPDADSITLKYKCYDMPLNTTLNYNQSTGAYEGTINYNQDPE
                     YLNVWELQGITINSKNNPKTLNRQDLEKLGLNLKDYNVTQECIIEDITSRKDVNKYLR
                     KTSSPITELTGSDRYETAVKISKEGWKNGSDKVVIINGDVSIDGIISTPLATTYNAPI
                     LLVEKNNVPNSVKSELKRLNPKDIIIIGDENAISKTTANQIKSTVNASQTRLNGSNRY
                     ETSLLIAKEIDKNHDVEKVYITNANGGEVDALTIAAKAGQDKQPIILTDKDSITDNTY
                     KWLKSEDLQNAYFIGGPQMISTNVINKVNGITKDSVTNNRVYGADRHETNANVIKKFY
                     TDDELEAVLVAKSDVLVDALAAGPLAANLKSPILITPKTYVSAYHKDNLEAKSANKVY
                     KIGGGLTSKVMSSIASSLSKHNTTPTEPGNSGGKTVMIDPGHGGSAPGNSSGGMIEKD
                     YNLNTSLATTEYLRSKGFNVIMTRDTDKTLSLGNRTALSNSLKPDLFTSIHYNGSTNK
                     QGHGVEVFYKLKDKNGGITKTVATNILNRILEKFKLTNRGIKTRVLPSDSTKDYLYVL
                     RSNDMPAVLVECAFLDNENDMSLINSSAKVKEMGTQIGKGIEDSLK"
     gene            4912..6825
                     /locus_tag="PC494_002441"
     CDS             4912..6825
                     /locus_tag="PC494_002441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3912936.1"
                     /translation="MEYLFEKSSLKEYGNEALDKYRELLDKTGNNSRCILLLVPNNNT
                     KIRYERSLRLNYSEELKITTYISFVKKELVKYWPLIIEKCDEISTKVVSPTFISNSLS
                     EYLIVQKVKEKRIQEGYFEDITGTNKSIANSIMTNINKSAFNLIDFDFIGEKIYSSKK
                     NKDSIYRFSYTQMDEIISYYINSLLSNSILDNALSIYLYNQYLLNDDFYLKNLFTEVR
                     YIIVDSLESSSNAEVDFITEALDNTLQSYIYFDYSRDYSVFNNVDIDYINEKIISKIK
                     PKEENIKKKEIRIEDLYLLPANIELNQSSQLYNEMLDLISEKVISLIEEDVSPRDIAI
                     ISPINNSILEHQIRDSLIEKNIDVFSTKKDKKAVDYPYGNALVVATCIFYGYLDFIKD
                     DEYLSFLETLLEINRIKAFKIFNETRHLSIDNIDEHSQYREILQYIEEKKKSDIKIHE
                     FLTQFYIDKMLNLKEGKKNVGLCKKIIAESESFSESLSLLGMKKEKIFIEALKSTIND
                     YYSVVDIEELKSKDKIVITTPYSYISSNIDRSIQIWVDIGSNAWNMKIEKDISNLIVL
                     RKSFEEKKIYTNEMEEYYKKYYLYNTVYNLLLNAKKIYAFKSEYAINGYIQESILYSI
                     LLKISHKGDKNYD"
     gene            6818..9037
                     /locus_tag="PC494_002442"
     CDS             6818..9037
                     /locus_tag="PC494_002442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HDF3912937.1"
                     /translation="MININYREDQIPIINYDNGTMAVPAVPGAGKTFIITNLVAKLLL
                     EQKHKGGKILILTYMNSAVNNFKGRIRKILEENKIDDTNSYEVMTIHSLAVKIIKEKP
                     EVVMLSEDFNIADDLQKSIILNECISRFRFEGGERAFRWFLKEQKDERWKEITLEAWE
                     RGFFEFAGNAISELKYKGISPDKLEEILSRGHKGMLKIILPIYKLYDRKLKQNGLLDY
                     DDILILAEKTLSLDEGLRKKFQTRYKYIFEDECQDSNEIQGNIIKIISSENKNLVRVG
                     DINQSITGTFSSSDPKFFKEFINSADFCYRMDMSNRSSKDILDLANTLVKYVTKEFRQ
                     KECRHALEDMQIKTVPNGMGYKENPNPEHYNINVKWYESWKIEIEQTARYVKGIKNKY
                     PDKSIGILVPFNEQVTQVAKELRENNLTFEELGPNSLNKRKVINNIAYIIDFMLHCDD
                     VEKLIVVLNKVFIDTDNEEEIKYFLEELKNYSTEEIIYNFEFSKLDNDLIEFKEESDI
                     YLSFKRGIDIIKQILEYPIIRLDLLVLFIGKKLNLEKEDKAVLDYISFYIKYLVSENI
                     NMDLEDVYNLLFDVKNRVFNHIIDVVYEINGYEPEPGSITLCNYHKSKGMEWDCVFLL
                     GLVEYNFPDNINQKFQSDKWYLKEKYKNPMAIIKSEVEAILKGSISTDYAHKTKIDSI
                     NEKIRLLYVGITRAKEMLVLSGSAYRDESDIGNKRKEQKPCIYLSRLNQHIIEKRSN"
     gene            9146..9976
                     /locus_tag="PC494_002443"
     CDS             9146..9976
                     /locus_tag="PC494_002443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family protein"
                     /protein_id="HDF3912938.1"
                     /translation="MNDKLKYFSYSQNSINTYKSCPLKFKYKYIDRINWKNDDVGSRE
                     YYETLKTGRDFHLICERYFSNIPLGIYFNEDDKNSKKFLKWMENIKKVVPIEKGKTYL
                     PEYEVRMTLNGDIIQAKYDLVVIGNNNIEIWDWKTESKKIDYKHVENRIQTIVYMFLA
                     KEVIPKVLKMDINVKDINMRYYQPEFDDLPITILYDEEKHEANRNKIQNYISMIKNTN
                     YEEHTYEDNLYNDIEKVYNKEERMCYRNKKHCKYCEFNKLCNGKEIDYSILEAEIYGT
                     "
     gene            9966..13433
                     /gene="addB"
                     /locus_tag="PC494_002444"
     CDS             9966..13433
                     /gene="addB"
                     /locus_tag="PC494_002444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddB"
                     /protein_id="HDF3912939.1"
                     /translation="MGLRFVLGRSGSGKSTYILDEIKKEAQKNETTSIILLVPEQYTF
                     EAENRVSKLFLGKEKDKYLRVRVLSFKTLSNIVFSQVGGLTDVNINSSGKAMMVYRAI
                     EDVSEELNVFSKSKSQSGFVSSITDMISEMKQYNISPEMLENISGELDNETLSLKLKD
                     ISKIYNSFEGKLHENYVDAQDMLTSLASKIELSSYLDGACVYIDEFTGFTPNQYNVIK
                     SILNKSKSVNISLTVDDINYIGYSKSDMFSRTKFTYSKLTQLCNEEGIKILPQVNLNT
                     GVIKRFEKVKELQHLERFYNAYPYKIYSNPTENIKIKEFNNLYSEVEEIAREIVHLVR
                     DKNVRYRDITIATRDLNRYDFLVHSIFNEYNIPNFIDKKREAKSNPIVILIISALEMK
                     NRRYGYETMFRYLKSGLIGIDNDDINLLENYVLANGIKGKKWFDEKWDYRITQSLSGQ
                     ESEFELELKEKINEIKNRVLEPIVILQEKLRGKNRVKEICRYIYEFLLDINMPETIES
                     LIVNFKDKGELDVANQYSQVWDIVVDILDQMVELMGDEIISLEKFIKLITLGFDEYEL
                     GLVPPSIDQVLVSSVDRMKNPDTKYLYLVGTTDGVFPLITKDSGILSDNDRESLGNKG
                     IEVDIDSKTRSFEEQFLVYKALTSTSKNLTITYPISDHEGKTLRPSIIISRLKKIFPN
                     IENKSYLVEENKSTDKDILKKITVKSPTFNELINIIKNYDSDGYNTEEINSIWLDIYR
                     YYLKDEVYSSITKKVIKGLSYTNQVHKIEEKKIRSLYKSNSLSISRLEKYAECPFAYF
                     IQYGLKAKKRKEYSFTPPDLGTFIHNILDRFSKELLQDNLTWRDIDEKYIELKIGIIV
                     DEIILKIPGYILNSSERYKYLAYRLKNMLTTAITIISQQIKQGSFEPIDYEVKFGNNG
                     KYPPIKMVLENGQEVSLIGQIDRVDEFEEGENKYIRIIDYKSGNKSISLTEIYYGLQL
                     QLLVYLDAILESAKDEDININPAAILYCRINNPIAKFNEDKDDEEIQEAILKELRMKG
                     LVVKDSHIVKEMDKSLIDGERKNSLVIPVGLTKDGNVGKSTSAISYEDFKLLRKYVRH
                     AIKDLCEEMLSGEIRIAPYKHKDGTSCDFCDYSAICQFDSTIKDNKYKNLNNKSNEEI
                     IKMMKGDVN"
     gene            13433..17260
                     /gene="addA"
                     /locus_tag="PC494_002445"
     CDS             13433..17260
                     /gene="addA"
                     /locus_tag="PC494_002445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HDF3912940.1"
                     /translation="MSSPKWTKEQLEVIESRECNLLVAAAAGSGKTAVLVERIIQMIT
                     SRENPIDIDKLLVVTFTNAAASEMRERIGDAIGKALDENPENKHLQNQLVLLNKSSIT
                     TIHSFCLDVIKSNFHRINLDPNFRIGDQTECAILKQEAIEEVFEDLYEERDEGFLNLV
                     ESYAERGGDKEVQDIILGIYSFAMASPEPKKWLIDSAERFNIDENFDFSQSIWARAIL
                     DTVKIEINGLCLNMERALKEVESIEELETFAEKLSVEYKKIADISQACNKSWDEAYKK
                     MASMSFENYVKGVKRISKDAPSYIKESKEKAKTIRDKTKKSLESIVSATFNKDNDSIR
                     EEIKYLYNIVKPISSVVLRFEEEYSNKKREKGIIDFNDIEHFALNILTDVDEKGNIVP
                     SDIAVGYRNKFYEIFIDEYQDSNLVQEVLLKAVANTETPNRFMVGDVKQSIYRFRQAK
                     PELFLQKYNNYNDKKGSSHRKIMLYKNFRSREEVVDAVNYIFENIMNENIGEIEYTEK
                     ERLNLGANFNVDTDEKSIIGGATEIHLIQKDNKLDDDIINDKDDRINNKENEIEEEEN
                     LDNIQLEARMVGNIIKDLMKVNEDGKIQKVYDKGIDGYRPVEFRDIVILLRATSAWAP
                     VFADELMNMDIPTYADVGVGYFDTIEIKTILSLLQIIDNPMQDIPLISVLKSPIFGFT
                     PEDLIDIRVQSKDKIFYEVLKSTAEYDGFTDSQNENESEFIPSEECINKSKDFLIKLK
                     EFKEKSMYMSTDEFIWYLYTRTGYYAYVGALPGGSQRQANLKVLFERAKQFEETSLKG
                     IFNFVNFIEKLKKSSSDMGSAKTLGENANVVRIMSIHKSKGLEFPVVICSAMGKNFNT
                     QDFKKSILYHHNLGYGPQFVDYERRISFPSIAKEALKSKINIENLSEEMRVLYVAFTR
                     AKEKLIITGSTRNIQDSIKRWSNGIESLDTISQYEILKGKNFLDWIMPCVLRHRDLSN
                     LLEEVGLDAVFNVEHNSKWYGKLWNKNDILVEKKSDEEKESIEEILEKIDVDNPDSDY
                     YSEIEEKLNYIYPYEFSTRKPATISVTEIKKIQNNYEEELINTIFEQKVILKKPLFIQ
                     NEEEREKISGTERGTIVHLVMEVLDLKNVSSVNDIKSQIRGFVSKGIITEKQASIVNP
                     YKIYKFFASNIGKRMLNAEIINREKSIYAQVNMKDIYIYEKLINNDDKKLYDNESVML
                     RGIVDAYFEEDNQIVLVDYKTDFVNEENINQIIEKYKKQLDLYADIIETLTGKSVKEK
                     CIYLFGVDEAVCY"
     gene            17306..18517
                     /locus_tag="PC494_002446"
     CDS             17306..18517
                     /locus_tag="PC494_002446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease SbcCD subunit D"
                     /protein_id="HDF3912941.1"
                     /translation="MRFIHTSDWHLGKSLEGHSRIEEQAKFCEEFIKIVESNEIDMVI
                     IAGDVYDTSNPPAQAEKLFYQTVSRLANNGQRCVLIISGNHDNPERLSAITPLAHEQG
                     ILIYGYPLSATIEAKYKGFEITYATQGCTKLNINGENIVVATLPYPSEKRLNEVFSSE
                     DEFEKQKNYSEKVGDIFRSLEENFRSDTINIAVSHIFVIGGESTESERPIQLGGSFLV
                     ERKDLPEKAQYTALGHLHKQQKASERLNAYYSGSPLQYSKDERAYTKGAYIVDIKAGE
                     KPIIEDVYFNNYKPIEVFKCNGIEEALDICEQNQDREIWSYFEINTDEIISQNEIKKM
                     KELLKDIIEIKPIITSCYEQESVDIKEKSMAELFREFYSFSKGVEPKGELMDLFLDII
                     SEEGESADETN"
     gene            18504..22031
                     /locus_tag="PC494_002447"
     CDS             18504..22031
                     /locus_tag="PC494_002447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HDF3912942.1"
                     /translation="MRPIRLELTGLNSYIDKQVIDFEKLIERGLFGIFGTTGSGKSTI
                     LDAITIAMYGNISRNTKEYINSVCDKAIISYEFEIGSKNTRRRYIVDRTIARSKTGTK
                     TSNARLIEVLNDNTQNVLADKVVEVNEKVAQVVGLTANDFTRSVVLPQDKFNEFLRLS
                     RADRRDMLERIFNLEKYGRSLGEKVKKRKNIQLQNLKDLKSKLSQYDGITEEVYNKIN
                     QELIELKNLEKDKNNALDLAQKSYEESKTVYEEQLKLEKNELRKNELDLKNSEIKEKI
                     ALVENDSNAKKVDPYISSVQNLEKKLDEDSFAVSNLEKKLAILNQELEVTKNRYEKIN
                     KIKNEEVPKLSEEKIRLQQAIKLEEELVLLDRELKELKESGINLNKTKVELEKVKQVS
                     ESRKDAVTKSIKEVEGKIDKVNISAELKQKIFLAYEYEKDYNNVLEEKNQKLNKLEEI
                     LKETENINLKVRYIDKDKNDVNRNLENLSLHLDVLLKKCPGKSADLLLKSEYVTELRN
                     KANNTKENEIKKSSIQDELKIILESKFNTEREVNLLNEKLENNRKNRDDLEKELEELK
                     YLNLASELRRELKENMPCPVCGSKHHENHDITKYDENISFVKEKLEKLEKEKISIRNN
                     IEELNAKVSGYLSIEKMKTKELEDVKGKLGGIPSSQLLKKLDEEQRKLALLKSNIQEW
                     EKEKESTENKVTLAKEEKNKIEKEELKIRESLNNYKKLTRDLNIEIEGLENKCKKIKQ
                     EYLGLKTITKVSNLLSKVKEIRENEKELELLSTGHSNLLKNRDSLDIKIRENESKLHE
                     IEIELIKARELYVEKKLSRDNKYKEVISITKGDLAKNLLHNVEENICKILEQEESSKK
                     KLEEQRLEYEKNIAEKHNIDGRLKTAKEQYKDQKSTLNKLLAENKFESIYAVKRALLD
                     TDAVKKLIEEILEHEEEQKLLSFKIKSSKEKLNGRSIKKEYFEQLKDEIYNLKVEIGN
                     ISKDIGANQNQLITLKDSLDKINDFNKQLKVVEHNVDLLEELDKCVQGNKFVEYVSTN
                     QLKYIALEASKRLDGITKGRYALEIDSTLNFVMRDNFNGGERRSIDTLSGGETFLTSL
                     SLALALSSQIQLKGSAPLEFFFLDEGFGSLDSELLEIVIESLERLHSNNLSVGIISHV
                     EELKNRVPVKLLVSSSEAGIGSKVKIEYS"
     gene            22162..23415
                     /locus_tag="PC494_002448"
     CDS             22162..23415
                     /locus_tag="PC494_002448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HDF3912943.1"
                     /translation="MLESPNNLIQIIFLIVLLIGSAFFSASETALMSLSKIRIRYMQD
                     EGVKGAKLVSSLIENPNKLLSSILVGNNVVNIAATSISTSLFIGLMGEKGVALATAVM
                     TVLVLIFGEITPKTIAANNSEKVSLLVSKPIKAIIFILRPIVWIFNIITNIIFKLFGI
                     TNKGAKSFITEEELKTMVNVSHEEGVLEMEEREIINNVFEFGDMQAKNAMVQRIDMVA
                     IDMEDSYDEIIQVFKTEKLSRMPVYEETIDDIVGILNIKDIIFLSDEEIESFDIKNYM
                     REPFFTYEFKKITQLLEEMKLEKSQMAIVVDEYGGTSGLLTIEDLVEVIVGDIEDEYD
                     EEEDEIQVIKEDEYIVDGSTKIGDVNELIGVNLESEEFDSIGGFIIGHLSRLPEENEV
                     IEVDNIRFCIESIEKNRIKKIRIYT"
BASE COUNT        10116 a         2270 c         4132 g         6920 t
ORIGIN      
        1 gtttttataa tttttttaga agtttatttt ttatgtactt atttataatt ttgggtaaaa
       61 acactttgat ataatttcaa aaattaaaag gttaaaaaac aaagtagaaa tttatgttaa
      121 ataaggagat taatatgaga agaaatacaa aattattaac aacagggatt ctttcaatgg
      181 caatcgtcgc acctacaatg gcatttgcta ctgaatctaa tgctatggaa aataacgctg
      241 atttaaatat aaacttagag aaaaaaagta tcgttttagg tagtacctca aaagtcagtg
      301 ttaagtttaa agaaaaacca gatgcagata gcattacatt aaagtataaa tgctatgata
      361 tgccattgga tacaacttta aactataatc aatcaactga gtcatatgaa ggaactatca
      421 attataataa agacccagaa tatctaaatg tttgggaact acaagggata acaataaaca
      481 gcaaaaataa tcctaaaact ttaaacaaac aagaactaga aaagatggga ttaaatttaa
      541 aagactataa tgtaacgcag gaatgtataa ttgaagatat aacttctaga aaagatgtaa
      601 ataaatattt aagaaaaact tctgcaccta ttacagaact tacaggaagt gatagatacg
      661 aaacagcagt taaaataagt aaagaaggct ggaaaaatgg ttcagataag gtagttataa
      721 taaatgggga tgtaagtata gatggcatta tatcaactcc actagcaact acatataatg
      781 cgccaatact tttggttgaa aaaaacaatg tacctaatag tgtaaaatca gaattaaagc
      841 gtttaaatcc tagagatgta attataattg gagatgagaa tgctatttct aaaactactg
      901 ctaatcaaat taaatcgact gtaaatgcta gtcaaacacg tctaaagggc tctaatagat
      961 atgagacatc tttattgata gcaaaggaaa tagataaaaa tcatgatgtg gaaaaagtat
     1021 acataacaaa tgctaatggc ggagaagtgg atgcacttac tatagcagca aaagcaggtc
     1081 aagacaagca accaattata ttaactgata aaaatagtat tacagacaac acatataaat
     1141 ggttaaagag tgaggattta caaaatgctt attttatagg tggccctcaa atgatatcaa
     1201 caaatgttat aaataaggta aatgatataa ctaaagataa tgttactaat aatagagtat
     1261 atggagcaga tagacacgaa acaaatgcaa acgtaataaa aaaattctat acagatgatg
     1321 agttagaggc tgttttagta gctaaatcag atgtacttgt tgatgcttta gcagcaggtc
     1381 cattggctgc gaacttaaaa tctccaatac ttataacacc aaagacatat gtatctgcat
     1441 accataaaga aaacttagaa gctaaatcgg caaataaggt atataaaata ggtggaggat
     1501 tgacttctaa ggtaatgagc tctatagcat catcattatc taaacacaat acaactccaa
     1561 cagaaccagg aaatagtggg ggcaagacag ttatgattga cccaggacat ggtggttcgg
     1621 acactggaac aacaggtaaa ccattagggg gtattagaga aaaagactat acattaaata
     1681 cttcacttgc gacaactgaa tatttacgtt caaagggatt caatgtaata atgacaagag
     1741 acacagataa gactttatct cttggaaata gaactgcttt atctaactct ttgagaccag
     1801 atttatttac gagtatacac tataatgcat ctgatacaac tgggaatggt gtagaagtat
     1861 tttataagct taaagataaa gatggaggga ctactaaaac tgtagctaca aatatattaa
     1921 atagaatctt agagaaattt aatctaaaaa atagaggtgc aaaaacaaga acactatcaa
     1981 ctgaccctac aaaagattat ttatatgttt taagaaataa tgatatgcca gctgtacttg
     2041 tagaatgtgc atttttggat aatgagaaag atatgagttt acttaataca tcaaataaag
     2101 taaaagaaat gggtacacaa ataggtaaag gcatagaaga ttcattaaaa tagtctacaa
     2161 tgagagcata gaaaaattta aaataaatta atctgcaatt ttaaatttaa actaaagcta
     2221 taagataaga atgtaattat aatagtaata aagactgtat atacattgtg catataagtg
     2281 cgaaatgagg tatatacagt ctttttatga ttaattgtaa aaggatttat attatatgaa
     2341 gaatttacat atcttaaggc tacagttaat tgtcaagagt tggagtattc atttgtaata
     2401 cacaataaaa gcttaattac tatattttat tgtgtgtttg tgtgtttttt gtggattttt
     2461 atgtcaataa atgatatagt atagataatt aaatgtatta aatatattta atttttttat
     2521 tttttgagtt ttataagttt atttttatat attacttata tattatttat attttgggtt
     2581 agatacactt tgacatattt tcaaaagtta aaagattaaa aataaagtag aaatttatgt
     2641 taagtaagga gattaatatg agaagaaata caaaattatt aacaacaggg attctttcaa
     2701 tggcaatcgt cgcacctaca atggcatttg ctactgaatc taatgctatg gaaaataacg
     2761 ctgatttaaa tataaactta gagaaaaaaa gtatcgtttt aggtagcaaa tcaaaagtta
     2821 gtgtcaaatt taaagaaaaa ccagatgcag atagcattac attaaagtat aaatgctatg
     2881 acatgccatt gaatacaact ctaaattaca atcaatcaac tggggcatat gaaggaacta
     2941 tcaattataa ccaagaccca gaatatctaa atgtttggga actacaaggg ataacaataa
     3001 acagcaaaaa taatcctaaa actttaaaca gacaagacct agaaaagctg ggattaaatt
     3061 taaaagacta taatgtaaca caggaatgta taattgaaga tataacttct agaaaagatg
     3121 taaataaata tttgagaaaa acttcttcac ctattacaga acttacagga agtgatagat
     3181 atgaaacagc agttaaaata agtaaagagg gctggaaaaa tggttcagat aaggtagtta
     3241 taataaatgg ggatgtaagt atagatggca ttatatcaac tccactggca accacatata
     3301 atgcaccaat acttttggtt gaaaaaaaca atgtacctaa tagtgtaaaa tcagaattaa
     3361 agcgcctaaa ccctaaagat ataattataa ttggagatga gaatgctatt tctaaaacta
     3421 ctgctaatca aattaaatca actgtaaatg ctagtcaaac acgtttaaat ggttctaata
     3481 gatatgagac atctttattg atagcaaagg aaatagataa aaatcatgat gtggaaaaag
     3541 tatacataac aaatgctaat ggcggagaag tggatgcact tactatagca gcaaaagcag
     3601 gtcaagacaa gcaaccaatt atattaactg ataaagatag tattacagac aatacatata
     3661 aatggttaaa gagtgaggat ttacaaaatg cttattttat aggtggtcct caaatgatat
     3721 caacaaatgt tataaataag gtaaatggaa taactaaaga tagtgttact aataatagag
     3781 tatacggagc agatagacac gaaacaaatg caaacgtaat aaaaaaattc tatacagatg
     3841 atgagttaga ggctgtttta gtagctaaat cagatgtact tgttgatgct ttagcagcag
     3901 gtccattggc tgcgaactta aaatctccaa tacttataac accaaagacg tatgtatctg
     3961 cataccataa agataattta gaagctaaat cagctaataa ggtatacaaa ataggaggag
     4021 gattgacttc taaggtaatg agctctatag catcatcatt atctaaacac aatacgactc
     4081 caacagaacc aggaaatagt ggtggcaaga cagttatgat tgacccaggg catggtggtt
     4141 cagcacctgg aaattcatct ggaggaatga ttgaaaaaga ttacaattta aatacttcac
     4201 ttgcaacaac tgaatattta cgttcaaagg gattcaatgt aataatgaca agagacacag
     4261 ataagacttt atctcttgga aatagaactg ctctatctaa ttcattgaaa ccagatttat
     4321 ttacaagtat acattataat ggctcaacta ataaacaagg tcatggtgta gaagtatttt
     4381 ataagcttaa agataaaaat ggagggatta ctaaaactgt agctaccaat atattaaata
     4441 gaattttaga gaaatttaaa cttacaaata gaggtataaa aacaagagta cttcctagtg
     4501 attctacaaa agattattta tacgttttaa gaagtaatga tatgccagct gtacttgtag
     4561 aatgtgcatt tttggataat gaaaatgata tgagtttaat aaactcatct gcaaaagtaa
     4621 aagaaatggg tacacaaata ggtaaaggaa tagaagattc attaaaataa atggaaataa
     4681 aaatatttaa aaacttaatg taaatttata gttgtaaatt tatactaaag tcaaaaaatg
     4741 aaatataagt gtatcaatag taagactgta tgtacatttg cacatgtgaa tgcaagtata
     4801 tatacagtct ttttttgtag ttaaatgcaa taatttgatt gtgttttgta aaatacacaa
     4861 tatgatataa ttagataata tacacttaat ttaattgagg aaggtgatta tatggaatat
     4921 ttatttgaaa aaagtagttt aaaagaatat ggaaatgaag ctttagataa atatagagaa
     4981 ttattagata aaactggtaa taattcaagg tgtattcttt tgttagtacc aaacaataac
     5041 acaaagatac gatatgaaag gtctctaaga ttaaattata gtgaagaact gaaaataaca
     5101 acatatataa gttttgtgaa gaaagaatta gttaaatact ggccactaat aatagaaaaa
     5161 tgtgatgaaa taagtacaaa ggttgtatct ccaacattta tatcaaatag tttaagtgaa
     5221 tatttaatag tgcaaaaagt taaggaaaaa aggatacaag aaggatattt tgaagatatt
     5281 acaggaacca ataaatccat agcaaatagt ataatgacta acataaataa gtctgcattt
     5341 aatttaattg attttgattt tattggagaa aaaatatatt catcaaagaa aaataaagat
     5401 agtatatata gattttcata cactcaaatg gatgaaatta tatcatatta tataaattcc
     5461 ttactatcaa attcaatttt agataatgca ttaagcatat atttatacaa tcaataccta
     5521 cttaatgatg atttttattt aaaaaactta tttacagaag tgagatatat aattgtggat
     5581 agccttgaaa gctcaagtaa tgcagaagtt gattttataa cagaagcatt ggataataca
     5641 ttacaaagtt atatatattt tgattatagt agggattatt ctgtatttaa taatgtggat
     5701 atagactata taaatgagaa aataatatca aaaattaagc ctaaagaaga aaatattaaa
     5761 aagaaggaga ttagaataga agatttatac ttattacctg caaatataga attaaatcaa
     5821 tcaagccaat tatataatga aatgttagat ttaataagtg aaaaagttat atctcttata
     5881 gaagaagatg tatctccaag agatatagca attatatctc ctataaacaa tagtatattg
     5941 gagcatcaaa ttagagattc tttgatagaa aaaaatatag atgtttttag tactaagaag
     6001 gataaaaaag ctgtggatta tccatatggg aatgcattgg tagtggctac atgtatattt
     6061 tatggatatt tagattttat aaaagatgat gaatacttaa gctttttaga aactctttta
     6121 gaaataaata ggataaaagc atttaagatt tttaatgaaa caagacattt aagtattgat
     6181 aatatagatg aacatagtca gtatcgtgag attttacagt atattgaaga aaaaaagaag
     6241 agtgatataa aaatacatga atttttaact caattttaca tagataaaat gttaaattta
     6301 aaagaaggta aaaagaatgt tgggttatgt aaaaagataa tagctgaaag tgagtctttt
     6361 agtgaaagtt taagtctact tgggatgaaa aaagaaaaga tatttataga agctttaaaa
     6421 agtacaataa acgattatta ctctgttgtc gatatagaag agttgaaatc caaagacaaa
     6481 atagtaataa ctactcctta ttcatatata tcatcaaata tagatagaag tatacaaata
     6541 tgggtagata taggaagtaa tgcttggaat atgaaaatag aaaaagatat aagtaattta
     6601 attgtactta gaaaatcttt tgaagaaaaa aagatttata caaatgaaat ggaagaatat
     6661 tataaaaaat actatctata caatacagta tataatttgt tattaaatgc aaagaaaatc
     6721 tatgcattta aaagtgaata tgcgattaat ggttatatcc aagagagtat attatatagt
     6781 atacttttaa aaatctcaca taaaggagat aaaaattatg attaatataa attatagaga
     6841 agaccagata ccaataataa attacgataa tggtactatg gcagtaccag cagtaccagg
     6901 tgctggaaaa acatttataa taacaaattt agtagctaaa ctattacttg agcagaaaca
     6961 taagggtggt aaaatattaa ttcttacata tatgaatagt gctgtaaata attttaaagg
     7021 tagaataaga aagattcttg aagagaataa aatagatgat actaattcgt atgaagtaat
     7081 gactatacac agtttggctg taaaaataat aaaggaaaag ccagaagttg taatgttaag
     7141 tgaggatttt aacatagctg acgatttgca aaaaagtatt atattaaatg aatgtataag
     7201 tagatttaga tttgaaggtg gagaaagagc ttttagatgg tttttaaagg agcaaaaaga
     7261 tgaacgctgg aaagaaataa ctcttgaagc ctgggaaaga ggtttttttg aatttgcagg
     7321 aaatgcaata agtgaactta agtataaggg aatttctcca gataaacttg aagaaatatt
     7381 gtcaagagga cacaaaggaa tgcttaaaat tattttacca atatataaat tgtatgatag
     7441 aaaattaaag caaaatggat tgctagatta tgatgatata ttaattttag cagaaaaaac
     7501 tttaagctta gacgaagggc ttagaaagaa gtttcaaact agatacaaat atatatttga
     7561 agatgagtgc caggactcaa atgaaattca aggtaatata ataaaaatta tatctagcga
     7621 aaataaaaac ctagttagag ttggagatat aaatcagagt ataacaggaa cattttcatc
     7681 atcagaccct aaatttttta aagaatttat aaatagtgca gatttctgtt ataggatgga
     7741 tatgtcaaat cgaagttcaa aagatatact tgatttagca aacactcttg tcaagtatgt
     7801 tacaaaggaa tttagacaga aagaatgtag acatgctctt gaagatatgc aaataaaaac
     7861 tgtgccaaat ggaatgggat ataaagaaaa ccctaatcca gaacattata atataaatgt
     7921 aaagtggtat gagagttgga aaattgaaat agagcaaact gctagatacg ttaagggtat
     7981 aaaaaataaa tatccagata aaagtatagg tatattggtt ccatttaatg aacaagtgac
     8041 acaagttgct aaagaactta gagagaataa tctaaccttt gaagaattag gaccaaattc
     8101 tttgaataaa aggaaggtta taaacaatat agcatatatt attgatttta tgttgcattg
     8161 tgatgatgta gaaaagttaa tagttgtact taataaagtt tttatagata ctgataatga
     8221 agaagaaata aagtattttt tagaagaatt aaaaaactat tctaccgaag aaattattta
     8281 taattttgaa tttagtaagt tagataatga tttaatagaa tttaaagaag aaagtgatat
     8341 atacttaagt tttaaaagag gaatagatat tataaaacag atattagaat atccaataat
     8401 aaggttagac ctcttagttt tgtttattgg gaaaaaactt aatttagaaa aagaagataa
     8461 agctgtactg gattatatat ctttttatat aaagtatcta gtatcagaaa atataaatat
     8521 ggatttagaa gatgtatata atttattgtt tgatgtaaag aacagggtgt ttaatcatat
     8581 aatagatgtg gtatatgaga taaatggata tgaaccagag cccggtagta taacactatg
     8641 taactatcat aagtcaaagg ggatggaatg ggattgtgtg tttttactag gtcttgttga
     8701 atataatttc cctgacaata ttaatcaaaa gtttcagagt gataaatggt atctaaaaga
     8761 aaaatataaa aaccctatgg caattattaa atcagaagtt gaagctatat taaaaggaag
     8821 tatttcaaca gattatgctc ataaaacgaa gattgattct ataaatgaaa agattagact
     8881 tttatatgta gggattacta gagcaaagga aatgttagta ctttcaggaa gtgcttatag
     8941 agatgaaagt gatataggga ataagagaaa agagcaaaaa ccatgtatat atttaagcag
     9001 acttaatcaa catattattg aaaaaaggtc aaattaatat ataataagtt attaaaagat
     9061 tgcttgaaat atatctaaaa ggggataaaa caatatgtac agtaagtaac tactaaaaaa
     9121 taaagttaag agagaagtga tatgagtgaa cgataaatta aaatattttt cttatagtca
     9181 aaattcaatt aacacatata aatcatgtcc attgaaattt aaatataaat atattgatag
     9241 aataaattgg aaaaatgatg atgttggtag tagagagtat tatgaaactt taaaaacagg
     9301 aagagatttt catttgattt gtgaaagata ttttagcaat atacctcttg gaatctattt
     9361 taatgaggat gataaaaata gtaaaaagtt tttaaagtgg atggaaaata taaaaaaagt
     9421 tgttcctatt gaaaaaggaa aaacgtattt gccagaatat gaagtaagga tgacattaaa
     9481 tggggatata atacaggcaa agtatgattt agttgtaatt ggaaataaca atatagaaat
     9541 atgggattgg aaaaccgagt ctaaaaagat tgactataaa cacgtagaaa atagaataca
     9601 aactattgtt tatatgtttt tagcaaaaga agtaatacct aaagttttaa aaatggacat
     9661 aaatgttaaa gatataaata tgagatatta tcaacctgaa tttgatgact taccaattac
     9721 cattttatat gatgaagaaa aacatgaagc aaatagaaat aaaattcaaa attatataag
     9781 tatgataaaa aacactaatt atgaagaaca tacatacgaa gacaatctat acaatgatat
     9841 agaaaaggta tataataaag aagaacgtat gtgctataga aataaaaagc attgcaagta
     9901 ttgtgaattt aataagttat gtaatggcaa agaaatagat tatagtattt tggaggcgga
     9961 aatttatggg acttaggttt gtattaggta gaagtggaag tggaaaatcc acctatatac
    10021 tagatgagat taaaaaagaa gctcaaaaaa atgaaacgac atcaattata cttttagttc
    10081 cagaacagta cacatttgag gctgaaaata gagtaagtaa actattttta ggaaaagaaa
    10141 aagataagta tctaagagtt agggtactta gctttaagac actaagtaat atagtttttt
    10201 ctcaagtagg aggattgaca gatgtaaata taaattctag tggaaaagca atgatggtat
    10261 atagagctat tgaagatgta agtgaagaat taaatgtgtt ttcaaaatca aaatcgcagt
    10321 ctggttttgt aagttcaatt acagatatga tatcagaaat gaaacaatac aatataagcc
    10381 ctgaaatgtt agaaaatata tctggagaat tggataatga aactttaagt ttaaaattaa
    10441 aagatataag taaaatatat aattcttttg aagggaaatt gcatgaaaat tatgtagatg
    10501 ctcaagatat gttaacttca ttggcaagta aaattgaatt aagcagttat ttagatggag
    10561 cttgtgttta tatagatgaa tttacaggtt ttacaccaaa tcagtacaat gtcataaaga
    10621 gtatattaaa taagtctaaa agtgttaata tctctttgac tgtagatgat atcaactata
    10681 ttgggtacag taaatctgat atgttttcta gaacgaaatt tacttattca aaattgactc
    10741 aattgtgcaa cgaagaaggc ataaaaatat tgccacaagt aaatttaaac acaggtgtta
    10801 taaaaagatt tgaaaaagtt aaggaattac agcacttaga aagattttat aatgcttatc
    10861 catataaaat atattcaaat ccaactgaaa atataaagat aaaagagttt aacaatttat
    10921 attcagaggt ggaagagata gccagagaaa ttgtacattt agttagagat aagaatgtca
    10981 gatatagaga tataaccatt gctacaagag atttaaatag atatgatttt ttagtacact
    11041 ctatatttaa tgaatataat ataccaaact ttatagataa gaagagagag gcaaaaagta
    11101 atccaatagt tattttaatt atttcagctt tagaaatgaa gaatagacga tatgggtatg
    11161 aaactatgtt taggtattta aaaagtggac ttataggaat tgataatgat gatataaatt
    11221 tactagaaaa ttatgtgttg gctaatggga ttaaaggtaa aaaatggttt gatgaaaaat
    11281 gggattatag aataactcaa agtctttcag gtcaagaaag tgaatttgaa ctggaattaa
    11341 aagagaaaat aaatgaaata aaaaatagag tattagagcc tatagtaatt ttacaagaaa
    11401 aattaagagg aaaaaataga gtaaaagaaa tctgtagata tatatatgaa tttttattag
    11461 atataaatat gccagaaact atagaaagtt taatagtaaa ttttaaggat aaaggggaac
    11521 ttgatgttgc aaatcaatac tcacaagttt gggacatagt agtggacata ttagaccaaa
    11581 tggtggaact tatgggtgat gaaataattt ctttagaaaa atttataaaa ttaataacct
    11641 taggttttga tgaatatgaa ttaggactgg ttcctcctag tatagaccag gtacttgtaa
    11701 gtagtgtgga tagaatgaaa aatccagaca cgaaatattt atacctagtt ggaactactg
    11761 atggtgtgtt tccgctgatt acaaaggata gtggaatatt gagtgataat gatagggaaa
    11821 gtcttggaaa caaaggaatc gaagttgata ttgatagtaa gactaggagt tttgaagaac
    11881 agtttcttgt atataaagct cttacttcga catctaagaa tttaaccata acatatccaa
    11941 tatcagacca tgaaggtaaa acgcttagac catcaataat tatatcaaga cttaagaaga
    12001 tatttccaaa tatagaaaat aaaagttatt tagtggaaga aaataaaagc actgataaag
    12061 atatacttaa aaaaataacg gttaaatccc ctacatttaa tgaacttata aacataataa
    12121 aaaattatga cagtgatggt tacaatacag aagagattaa tagtatttgg ttagatatat
    12181 ataggtacta tttaaaagat gaagtctata gttctataac aaaaaaagtt ataaaaggtc
    12241 ttagttatac taatcaagtt cataagattg aagagaaaaa aataaggtca ttgtataaaa
    12301 gtaattctct tagcatatct aggcttgaaa aatatgctga atgtccattt gcttatttta
    12361 tacaatatgg tctaaaagca aaaaagcgta aagagtattc atttacacca ccagatttag
    12421 gaacttttat tcataatatt ttagataggt tttcaaaaga acttttacaa gataatttaa
    12481 cttggagaga tattgatgaa aaatatatag aattaaagat aggtataata gttgatgaaa
    12541 taattttaaa gataccagga tatatattaa atagttctga gaggtataaa taccttgcat
    12601 atagattaaa gaatatgttg acaactgcta taactataat tagtcagcaa ataaaacaag
    12661 gttcatttga accaatagat tatgaagtta aatttggcaa caatggaaaa tatccaccta
    12721 taaaaatggt gttagaaaat ggacaagaag taagtttaat tggacaaata gatagagttg
    12781 atgaatttga agaaggagaa aataaatata taagaataat agattataag tcaggcaata
    12841 agtccataag tctaacagaa atatattatg gtctacaatt acaattactt gtgtatttag
    12901 atgcaatcct tgaaagtgca aaggatgaag atataaatat aaatccagct gcaatactat
    12961 attgtagaat aaataatcca atagcaaaat ttaatgaaga taaagatgat gaagaaatac
    13021 aagaagcaat attaaaagaa cttagaatga aggggcttgt agtaaaagac tctcacatag
    13081 ttaaagagat ggataaatca ttaatagatg gagaaaggaa aaactcttta gtaataccag
    13141 taggtcttac taaggatgga aatgtaggta aaagtacttc agcaataagc tatgaggatt
    13201 tcaaactgct tagaaaatat gtaaggcatg ctataaagga tttatgtgaa gaaatgttaa
    13261 gtggagaaat acgtatagct ccatataaac ataaagatgg aacatcatgt gacttttgtg
    13321 attactctgc tatatgtcag tttgattcaa ctataaaaga taacaagtat aaaaatttaa
    13381 ataataagag taatgaagag ataataaaaa tgatgaaagg agatgttaat tagtgagttc
    13441 tcctaaatgg acaaaagagc aattagaagt tatagaaagt agagaatgca atttattggt
    13501 tgctgctgct gctggttcag gaaaaacagc cgttctagtt gagcgtataa ttcaaatgat
    13561 aacaagtaga gaaaatccaa ttgatataga taagttatta gttgttacat ttactaatgc
    13621 tgctgcgtca gaaatgagag agaggatagg ggatgctata ggaaaagcct tagatgaaaa
    13681 cccagaaaat aaacatttac aaaaccaact tgttttatta aataaatcta gtattacaac
    13741 aatacactca ttctgtttgg atgttataaa atcaaacttt catagaataa acttagaccc
    13801 taatttcaga ataggagacc aaactgaatg tgctattttg aaacaagaag caatagagga
    13861 agtatttgaa gatttatatg aagaaagaga tgaggggttt ttaaatttag ttgaaagtta
    13921 tgcagaaaga ggaggagata aagaagtaca agatattatc ttgggaatat attcatttgc
    13981 aatggcttct cctgaaccta aaaaatggtt gattgactca gcagaacgat ttaatattga
    14041 tgaaaatttt gatttttcac agtctatttg ggctagagct atattagaca ctgtaaaaat
    14101 agagattaat ggtctttgtc taaatatgga aagggcatta aaagaagtgg aatcaataga
    14161 agaattagaa acttttgcag aaaagttatc tgttgaatat aaaaaaattg ctgacatttc
    14221 acaagcatgt aataaatctt gggatgaggc atataaaaag atggcaagta tgtcctttga
    14281 aaattatgta aaaggagtaa aaagaatttc aaaagatgct ccttcgtata taaaagaatc
    14341 aaaagaaaag gcaaaaacta taagagataa gactaagaag tctttagaaa gtatagtaag
    14401 tgctacattc aataaagata atgattctat tagagaagaa ataaaatatc tttataacat
    14461 agttaaacca atatctagtg ttgtactgag atttgaagag gaatatagca ataagaaaag
    14521 agaaaaagga ataatagatt ttaacgatat agagcatttt gcattaaata tacttacaga
    14581 tgtagatgaa aaaggtaata ttgtaccttc tgatatagca gttggatata gaaacaagtt
    14641 ttatgaaata tttatagatg aatatcagga tagtaatcta gtgcaggaag tactgcttaa
    14701 agctgttgca aatacagaaa ctccaaatag atttatggtt ggtgatgtaa aacagagtat
    14761 atatagattt agacaagcaa agccagaatt atttttgcaa aaatataata actataatga
    14821 taaaaaggga agttcccata gaaaaataat gctttacaaa aattttagaa gtagagaaga
    14881 agttgtagat gctgtaaatt atatatttga aaatataatg aatgagaata taggagaaat
    14941 tgaatataca gaaaaagaaa gactaaattt aggtgcaaat tttaatgtgg atacagacga
    15001 gaaatctatt attggtggag caacggagat acacctaata caaaaagata ataaacttga
    15061 tgatgatatt ataaatgata aagacgatag aattaataac aaagaaaatg aaatagagga
    15121 agaagaaaat ttagataata tacaacttga ggctagaatg gttggaaaca ttatcaaaga
    15181 tttaatgaaa gtcaatgaag atggaaaaat tcaaaaggtc tatgataagg gaatagatgg
    15241 atatagacct gtggaattta gagatatagt tattctttta agagctacat ctgcatgggc
    15301 tccagtgttt gcagatgaat tgatgaatat ggatatacca acgtatgctg atgttggagt
    15361 ggggtatttt gatacgattg aaataaaaac aatattgtca ttacttcaaa taatagataa
    15421 tccaatgcaa gatatacctc ttatatctgt attaaaatca cctatatttg gatttacacc
    15481 agaggatttg attgatatta gagttcagag taaagataaa attttttatg aggttttaaa
    15541 aagtacagca gagtatgatg gatttacaga ttctcaaaat gaaaatgagt ctgagtttat
    15601 accaagtgaa gagtgcataa acaaaagtaa agatttttta attaagctaa aggaatttaa
    15661 agaaaagtca atgtacatga gtacagatga atttatatgg tacttgtaca caaggactgg
    15721 atactatgcc tatgttggag cattgccagg tggaagtcaa agacaagcta atttaaaagt
    15781 attgtttgag agagcaaaac aatttgaaga aaccagtctt aaaggaatat tcaactttgt
    15841 aaattttata gagaaattaa aaaaatctag ttctgatatg ggaagtgcaa aaacacttgg
    15901 tgagaatgca aatgttgtta gaataatgag tattcataaa agtaaaggtc tagaatttcc
    15961 agtagtcata tgctctgcaa tgggtaaaaa tttcaatact caagatttta aaaagagtat
    16021 tttatatcat cataatttag ggtatggacc tcaatttgta gactatgaga gaaggatttc
    16081 ttttccaagt atagccaaag aagcattaaa aagcaaaata aatatagaaa atttatcaga
    16141 agagatgaga gttttatatg ttgcatttac aagagctaaa gaaaaattga ttataactgg
    16201 ttctactaga aatatacaag atagtataaa gagatggtca aatggaattg aaagtttaga
    16261 tacaatatca caatacgaga tattaaaagg taaaaatttt ttagattgga taatgccttg
    16321 tgtattaaga catagggatt tatctaatct actagaagaa gtaggattag acgcagtttt
    16381 taatgttgaa cataattcaa aatggtatgg aaagttgtgg aataagaatg atattttagt
    16441 ggaaaagaag agtgatgaag aaaaagaaag tattgaagaa attcttgaaa aaatagatgt
    16501 agataatcct gacagtgatt attacagtga aatagaagaa aaattaaact atatatatcc
    16561 atatgaattt agtacaagaa aacctgctac tatatctgtt acagaaataa aaaagataca
    16621 aaataattat gaagaagagt taataaatac tatatttgaa caaaaagtaa tattaaaaaa
    16681 gcctctattt attcaaaatg aagaagaaag agaaaaaata agtggaacag aaagaggtac
    16741 aatagtccat ttagttatgg aggttttaga cttaaaaaat gtaagtagtg taaatgatat
    16801 aaaatcacaa ataagaggtt ttgtttcaaa aggtataata acagaaaaac aagctagtat
    16861 agtaaatcca tataaaatat ataaattttt tgcctctaac ataggaaaaa gaatgttgaa
    16921 tgctgaaatt ataaatagag aaaaatcaat ttatgcacaa gtaaatatga aagacatata
    16981 tatttatgaa aagcttataa acaatgacga taaaaaactt tatgataatg aaagtgtcat
    17041 gttaagaggt atagttgatg cttattttga agaagataat caaatagttt tggtggatta
    17101 taaaacagat tttgtaaatg aggaaaatat aaatcaaata atagagaaat ataaaaaaca
    17161 gttggattta tatgcagata ttattgaaac tttaactggt aagtcagtaa aagagaaatg
    17221 tatatattta tttggagttg atgaagctgt ttgttattag tttttatata taaattaaac
    17281 ctaaaagata gaggaagggg aaaaaatgag atttattcat acatcagatt ggcatctagg
    17341 gaagtcccta gaaggccatt ctagaattga ggaacaagca aagttttgtg aggaatttat
    17401 aaaaatagta gaatcaaatg aaatagatat ggttataatt gctggagatg tatatgatac
    17461 ttctaatcca ccagcacaag cagaaaaact attttatcag actgtatcaa gacttgccaa
    17521 taatggtcag aggtgtgtat taataatttc aggaaatcat gataatccag agagactctc
    17581 tgcaataaca cctctagcac atgaacaggg gatacttata tatggttatc cattaagtgc
    17641 tacgatagaa gctaagtata aagggtttga aataacatat gcaactcagg gatgtacaaa
    17701 actgaatata aatggagaaa atattgtggt tgctacatta ccttatccaa gtgaaaaaag
    17761 attaaatgaa gttttttcaa gtgaagatga gtttgagaaa caaaaaaatt attctgaaaa
    17821 ggtaggagat atatttagaa gtttagaaga aaattttaga agtgatacta taaatatagc
    17881 cgtatcacat atatttgtaa taggtggaga gagtactgaa tcagaaagac ctatacagtt
    17941 aggtggaagt tttttagttg aaagaaaaga tttgccagaa aaggctcaat atactgcact
    18001 aggtcattta cataaacaac aaaaagcttc cgaacgttta aatgcatact attctggttc
    18061 tccacttcaa tatagcaagg atgaaagagc gtataccaaa ggggcataca tagtggatat
    18121 aaaagctggt gaaaaaccaa taattgaaga tgtatatttt aataattaca aacctataga
    18181 agtatttaaa tgtaatggaa tagaagaagc actagatata tgtgagcaaa atcaagatag
    18241 agagatttgg tcatattttg aaataaatac tgatgagata atatcacaga atgaaattaa
    18301 aaaaatgaag gaactattaa aagacataat agaaataaaa ccaataataa catcttgtta
    18361 tgaacaagaa agtgtagata taaaagaaaa gtctatggca gagttgttta gagagttcta
    18421 ttcttttagt aaaggtgtag agccaaaagg agaacttatg gatttatttc tagatataat
    18481 aagtgaagaa ggtgaatcag cagatgagac caattagatt agaacttaca gggcttaata
    18541 gctatattga taaacaagtt atagactttg aaaaattaat tgaaagaggt ttgtttggga
    18601 tatttggaac tactggaagt ggaaaatcta caatcttaga tgcaataact attgctatgt
    18661 atggaaatat atccagaaat acaaaagaat atataaacag tgtgtgcgat aaggcaatta
    18721 tatcatacga gtttgagata ggaagcaaaa acactagaag aagatacatt gtagatagaa
    18781 ccattgctag aagcaaaaca ggaacaaaga cctctaatgc tagattaata gaagtattga
    18841 atgacaatac ccaaaatgtt ttagctgata aagttgtgga agtaaatgaa aaagtagcac
    18901 aggttgtagg attaacggca aatgatttta ctaggtcagt agttttacca caagacaaat
    18961 ttaatgagtt tctaagatta tcacgtgcag atagaagaga catgttagag agaattttta
    19021 atcttgagaa atatggaaga agtcttggag aaaaagtgaa aaagagaaaa aatatacagt
    19081 tacaaaattt aaaagatttg aaatcaaaat taagtcaata tgatggaatt acagaggaag
    19141 tatacaacaa aataaaccaa gaattaatag agttaaaaaa tttggaaaaa gataagaata
    19201 atgctttaga cctagctcaa aaatcttatg aagaaagtaa aacagtatat gaagaacaat
    19261 taaagttaga aaaaaatgaa cttagaaaaa atgagcttga tttaaaaaat agtgagataa
    19321 aagaaaagat tgctcttgta gaaaatgata gtaacgctaa aaaggtagac ccatacataa
    19381 gttcagttca aaatctagaa aaaaagctag atgaagatag ttttgcagta agtaatttag
    19441 aaaagaaatt agcaatatta aatcaggagc ttgaagttac aaaaaataga tatgaaaaaa
    19501 taaacaaaat taagaatgaa gaagtcccta aattgagtga agaaaaaata agattgcaac
    19561 aagcaataaa attagaagaa gagttagttt tattagatag agagttaaaa gagctaaaag
    19621 aaagtggaat taatttaaat aagactaaag ttgaattaga aaaagtaaag caggtgtcag
    19681 agtccagaaa agatgcagtt actaaatcta taaaagaagt tgaaggaaag attgataaag
    19741 taaatataag tgcagaatta aaacaaaaaa tatttctagc atatgaatac gagaaagatt
    19801 acaacaacgt attggaagaa aaaaatcaaa agctaaataa actagaagaa atactcaaag
    19861 agacagaaaa tataaattta aaagttagat atattgataa agataagaat gatgtaaatc
    19921 gtaatttaga aaatttatca cttcacttgg atgttcttct taaaaaatgt cctggtaaga
    19981 gtgctgattt acttttaaaa tctgaatatg ttactgaatt aagaaataaa gcaaataata
    20041 ctaaagaaaa tgaaattaag aaaagcagta tacaagatga attaaagata atacttgaaa
    20101 gtaagtttaa tactgaaagg gaagtaaatt tactaaatga aaaacttgaa aataatagaa
    20161 agaacagaga tgacttagaa aaagaattgg aagaactaaa gtatttaaat ttagcctctg
    20221 aacttagacg tgaattaaaa gaaaatatgc cttgtccagt ttgtgggtca aaacatcatg
    20281 aaaatcatga tataactaag tatgatgaaa atatatcttt tgtcaaagaa aaactggaga
    20341 aattagaaaa agaaaaaata agtataagaa acaatataga ggaattaaat gctaaagtaa
    20401 gtgggtattt atctatagaa aaaatgaaga ctaaagaact tgaagatgta aaaggaaaac
    20461 taggggggat tccatctagt caattattaa aaaaacttga tgaagaacaa agaaaacttg
    20521 cattgttaaa atctaatatt caggagtggg agaaagaaaa agagagtact gaaaataaag
    20581 taacattagc taaagaagaa aaaaataaaa ttgaaaaaga agaattaaaa ataagagaga
    20641 gtctgaataa ttataagaaa ttaacaagag atttaaacat agaaatagaa ggtttagaaa
    20701 ataaatgtaa aaaaattaaa caggaatacc taggattaaa gacgattact aaagtctcta
    20761 atctattgtc aaaagtaaaa gaaataagag agaatgaaaa agaattagaa ttactaagta
    20821 ctgggcattc aaatttatta aaaaatagag actcactaga tattaaaata agagaaaatg
    20881 agagtaaact acatgaaata gagatagaat taataaaggc tagagaatta tatgtagaaa
    20941 agaaattgag tagggataat aagtataaag aagttattag cataacgaaa ggtgatttag
    21001 ctaaaaatct tttacataat gttgaagaaa atatatgtaa gatattagaa caagaagaat
    21061 caagtaagaa aaaattggaa gagcaaagat tagaatatga aaaaaacatt gctgaaaagc
    21121 acaatataga tggtagactt aaaactgcta aggaacaata taaagaccaa aaatcaacac
    21181 taaataaact attagcagaa aataaatttg aaagtatata tgcagtaaaa agagctttat
    21241 tagatactga tgcagtaaaa aaattgattg aagaaatact agagcatgaa gaagaacaaa
    21301 agttattatc atttaaaata aaatcatcaa aagaaaaatt aaatggaaga agcataaaga
    21361 aggagtactt tgaacagtta aaagatgaaa tttataattt gaaagtagaa ataggaaata
    21421 tatccaaaga tattggagct aatcaaaatc agttaataac attaaaagac tctttagata
    21481 agataaatga ttttaataaa caacttaagg tagttgaaca caatgtggac ttattggaag
    21541 aattagataa atgtgtacaa ggaaataaat ttgtagaata tgtttctaca aaccaattaa
    21601 aatatatagc attggaagca tcaaaacgat tggatggaat aacaaaagga agatatgcac
    21661 ttgaaattga ctcaacacta aactttgtaa tgagagataa ctttaatgga ggagaaagaa
    21721 gaagcattga tactctatct ggtggagaga cattcttgac atctctatca ttagcacttg
    21781 ctctttcatc tcaaatacaa ttaaagggaa gtgcaccatt agaatttttc tttttagatg
    21841 aaggttttgg ttcattagat agtgaacttt tagaaattgt tatagaatcc ttggaaagat
    21901 tgcatagtaa taatctaagt gtgggtataa taagtcatgt cgaggaactt aaaaatagag
    21961 ttcctgttaa gctattagtt tcatctagtg aggctggaat aggttcaaaa gtaaaaattg
    22021 aatatagtta gaaaatatat gttaattgaa tatattatct aatatttcca aataatatgt
    22081 aattgtgata taataaaaac taatattaaa gttatttata attaatatta atataaaaac
    22141 atgtaagtag gagtgtggta agtgttggaa tcgcccaata atttgattca gattattttt
    22201 ttaatagtat tacttatagg gtctgcattt ttctcagcat ctgaaacggc cttaatgtcg
    22261 ttgagtaaaa tcagaatcag atatatgcaa gatgaaggag ttaaaggagc taagttagta
    22321 agttcattaa tagaaaatcc aaataagctt ttaagttcta tattggttgg aaataacgtc
    22381 gtaaatatag cagcaacatc catatcaaca tctttgttta taggattaat gggagaaaaa
    22441 ggagtggcac ttgctacagc tgttatgaca gtattagtat taatatttgg tgagattact
    22501 ccaaaaacaa tagcagcaaa taattcagaa aaggtttctc tattagtatc taaacctata
    22561 aaagcaatta tatttatatt aagaccaata gtatggatat ttaatataat tacaaatatt
    22621 atatttaaat tatttggtat aacaaataaa ggagctaaat cattcataac tgaagaagag
    22681 ctaaaaacta tggtaaatgt aagtcatgaa gaaggcgtcc ttgaaatgga agagagagaa
    22741 atcataaata atgtttttga atttggagat atgcaagcta aaaatgcaat ggtacaaaga
    22801 atagatatgg tagctataga tatggaagat agttatgatg agataataca ggtatttaaa
    22861 actgaaaaat taagtagaat gcctgtgtat gaagaaacta tagatgatat cgtaggaata
    22921 cttaatataa aagatattat atttttatct gatgaagaaa tagagtcatt tgatattaaa
    22981 aattatatga gagaaccttt tttcacgtat gagttcaaaa agataacaca acttcttgaa
    23041 gagatgaaac ttgaaaaaag tcagatggct atagttgtag atgagtatgg tggaacatct
    23101 ggacttttaa ctatagaaga tttagtagaa gtcattgttg gagatataga ggatgaatat
    23161 gatgaagaag aggatgaaat acaagttata aaagaagatg agtatattgt agatggaagt
    23221 actaaaattg gtgatgttaa tgaacttatt ggtgtaaact tggaatctga ggagtttgat
    23281 tccataggag gttttataat tggacaccta agcagattgc cagaagaaaa tgaagtaatt
    23341 gaagttgata atataagatt ttgtatagaa agtatagaaa aaaatagaat taaaaaaata
    23401 agaatatata cataatgtaa taatgttctt aaatttat
//
LOCUS       DAMKNB010000056        23383 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.058, whole genome shotgun sequence.
ACCESSION   DAMKNB010000056 DAMKNB010000000
VERSION     DAMKNB010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 23383)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23383)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23383
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.058"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            complement(76..1347)
                     /gene="serS"
                     /locus_tag="PC494_002449"
     CDS             complement(76..1347)
                     /gene="serS"
                     /locus_tag="PC494_002449"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000884181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HDF3912944.1"
                     /translation="MLDIKRIRENLDCIKKAMERRGEKDFNLDEVVKLDDERRKILQE
                     VEVMKNELNTASKNIPNLIKEGKDVENEKIKLKELSDKIKVIDQNLKEVEDKMEYLLM
                     RIPNVPHPEVPQGETDEDNVEVRTWGKTTTFDFESKAHWEIGTELGILDFETASKITG
                     SRFTLYKGLGARLERALLNFYLDTNTKVNGYTEVIPPFMANRNSFLGTGQLPKFEEDM
                     FKIEGLDYFMIPTSEVPLTNIHANEILKFEQLPINYTAYTPCFRSEAGSAGRDTRGLV
                     RQHQFNKVEMVKIVAPEESYNELEKLTNNAETMLQLLNLPYRVVKICTGDLGFTASFK
                     YDVEVWMPSYNRYVEISSCSNCEDFQARRAGIRFKRDKDSKAEYVHTLNGSGLAIGRS
                     VAAILENYQQEDGSVVVPEVLRPYMGVSVIK"
     gene            complement(2163..3767)
                     /locus_tag="PC494_002450"
     CDS             complement(2163..3767)
                     /locus_tag="PC494_002450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HDF3912945.1"
                     /translation="MKEKIYYNGNIITMEDSICGDAILIKDKIIKKIGTKEEVFALKN
                     KDTEIIDLQGKTLMPSFIDSHSHLIAFATTLKLVPLEDATSFKDIVKKIQDFKESNNI
                     KKGDWIIGFSYDNNFLEENKHPDKSVLDSASSENPILISHASGHMGVANTLGLKQLGV
                     TNETRDPEGGHIGRVEGSEEPNGYLEENAFFNVASKIKQPSSNEIFNSIEKAQNIYLS
                     YGITTAQEGLMEENQFNILKAMANQNKLKMDVVGYVNLKKSKSVADNNREFIKKYINR
                     FKIGGYKIFLDGSPQGKTAWLSRPYENSDDGYCGYPIYKDEEVEKFIDISLKEKMQLL
                     THCNGDAAADQLIDAFEKVLNLKEQSSENHIRPVMIHAQTVREDQIDDMKVINMIPSY
                     FVAHTYYWGDIHIKNLGEDRAFKISPLKTTIEKGLIYTLHQDTPVIAPNMLETVWCAV
                     NRITKKGIQIGENEKISPLDALKGVTINAAYQYFEEDKKGSIKEGKLANLIILDENPL
                     TIDPMKIKDIKVLQTIREGEVLYSLK"
     gene            4153..5079
                     /locus_tag="PC494_002451"
     CDS             4153..5079
                     /locus_tag="PC494_002451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon-nitrogen hydrolase family protein"
                     /protein_id="HDF3912946.1"
                     /translation="MSKENKNVRIAVVQASPVIMDLEKTVEKALGLIKEAGRKGANIV
                     VFPEAFIPAYPRGLSFGFVVGSRTMEGREDWKRYYDNSVPVPSATTDLLGKAAQEAGV
                     YLSMGITERDGNDINCTLYCTNLFFSPEGKLIGKHRKLKPTGTERCIWGEGDGSTLTV
                     VDTPYGKMGSLICWENYMPLARTALYAKGVKLYIAPTADSREEWQATMKHIALEGRCF
                     VIGCNQYVEKNMYPTDLNYYKELDAEPEIMCPGGSCIVDPFGKYVAGPIFNKEEMLIA
                     DLDLEKIVLSRLDFDSEGHYSRPDVFELIVHE"
     gene            complement(5199..6197)
                     /locus_tag="PC494_002452"
     CDS             complement(5199..6197)
                     /locus_tag="PC494_002452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhdH/YhfP family quinone oxidoreductase"
                     /protein_id="HDF3912947.1"
                     /translation="MNKKFKSLYITEEEGNFRRNIVEREVDTLPEGEVLIKVKYSSLN
                     YKDALSANGNKGVTRKYPHTPGIDASGIVESSSCDDFKIGEEVLVTGYDLGMNTSGGF
                     SEYIRVPSSWVVKLPKNLSLKEAMDYGTAGFTAALSVYKFIDSVDKNMGDVLVTGGTG
                     GVAVIATKILIKLGYSVVVSTGKLEEQKEVLLNLGVKDVIHRSEVDDNSGRPLLRPRW
                     AGVIDTVGGNTLATAIKTTNYCGAVTTCGNAGGVDFTSSVYPFILKGITLYGIDSVDC
                     PMNLRLKIWDLLSNEWKLDDLDDMVNVVSLEELNDSIDSIMAGKHVGRTVVDLEKI"
     gene            6301..6738
                     /locus_tag="PC494_002453"
     CDS             6301..6738
                     /locus_tag="PC494_002453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HDF3912948.1"
                     /translation="MEDKYIVHFISKTKASMIKFIENKLSKNGLGELIPTHGNILTAL
                     YENNGILTMKEIAAKIGKDKSTVTVLVNKLINLGYLERQKCTNDKRITYIKLTKKALL
                     IEDTFNSISTQVKETAYHNITENEKQEFLRILKKINDNFKNAD"
     gene            6824..7411
                     /locus_tag="PC494_002454"
     CDS             6824..7411
                     /locus_tag="PC494_002454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rubrerythrin family protein"
                     /protein_id="HDF3912949.1"
                     /translation="MNLKDSKTKENLLRAFAGESQARNRYNISASVAKKEGLYIIESL
                     FNYTADQEKSHAKQFFSKLKEFAGENISISGAYPVDLYDKTAQHLKAAQHNELQEWDD
                     VYKNFGKTAREEGFESIAKLFENIAEIEKVHGDRFGRYATDLEEGTLFRRNEDIQWIC
                     THCGHIHIGKEAPKACPVCLHPQGYFLDFKNSLFE"
     gene            complement(7711..8121)
                     /locus_tag="PC494_002455"
                     /pseudo
     CDS             complement(7711..8121)
                     /locus_tag="PC494_002455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861712.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4004 family protein"
     gene            complement(8238..9356)
                     /locus_tag="PC494_002456"
     CDS             complement(8238..9356)
                     /locus_tag="PC494_002456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDF3912950.1"
                     /translation="MAVVEKAYKFRMYPNKKQQELINKTFGCCRFVYNKYLAKRIEVY
                     KNNKETFTYKQCSSDLTNLKKELKWLKEPDKFSLQNALKDLDNAYKKFFKEKAGFPKF
                     KSKKINRFSYKTNFTNGNIMYCGQYIKLPKLGMVKVRDKQVPQGRILNATISKEPSGR
                     YYVSLCCTNVDIEVFENTNNQIGLDLGIKEFCISSCGDFIENPKYLKKSLNKLAKLQR
                     ELSRKTIGSLNRNKARLKVARLQEHIANQRNDFLQKLSTKLIKENDIICIEDLQVKNM
                     IRNRKLSRLISDVSWSEFVRQLKYKANWHGRQIVKVGKFFASSQICNKCGYKNEEMKD
                     LNIREWICPSCNETHDRDINASINILKEGLRLITIQNK"
     gene            complement(9358..9765)
                     /gene="tnpA"
                     /locus_tag="PC494_002457"
     CDS             complement(9358..9765)
                     /gene="tnpA"
                     /locus_tag="PC494_002457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013824389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
                     /protein_id="HDF3912951.1"
                     /translation="MEVTHGRGYVYLVQYHIVWCVKYRHPVLTNEIEEDLINILNKIA
                     EDNKFQILECNSDKDHIHLLINCSPQHYIPDIIKALKGVSARLLMKKHGEQLKKKLWG
                     GHLWNPSYFVATVSENTEEQIRKYINNQKKQVK"
     gene            complement(10334..10543)
                     /locus_tag="PC494_002458"
                     /pseudo
     CDS             complement(10334..10543)
                     /locus_tag="PC494_002458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861712.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4004 family protein"
     gene            complement(10645..11193)
                     /locus_tag="PC494_002459"
                     /pseudo
     CDS             complement(10645..11193)
                     /locus_tag="PC494_002459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426706.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(11552..13462)
                     /gene="phnW"
                     /locus_tag="PC494_002460"
     CDS             complement(11552..13462)
                     /gene="phnW"
                     /locus_tag="PC494_002460"
                     /EC_number="2.6.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-aminoethylphosphonate--pyruvate transaminase"
                     /protein_id="HDF3912952.1"
                     /translation="MKKIYGEKIKAVVFDWAGTTVDYGCFAPLNVFIEIFKRRGIDVT
                     MEEARKPMGKLKIDHIREMCEMDRIKNIWSDKFGKVPTEDDVNELYAEFEPMLFETLE
                     EYTTPIPHVVETIEKLRKNGLKIGSTTGYTREMMNIVEPNAAKKGYSPDFLVTPSEVS
                     QGRPYPWMCYKNAEALGVSPMSSMVKVGDTISDVKEGVNAGMWSVAVIKGSSELGLTQ
                     EEVENMDKEELKAKMSIVSKKFKEAGAHFVIETMAELEDILIKIENETIKSDFVPEND
                     YILLTPGPLSTTKSVRASMLKDWCTWDVEYNNLVQDVRRRLVSLATQNTDKYTSVLMQ
                     GSGTFSVEAIIGSTISKDGKLLVIANGAYGKRMKDICNYLNIQFVDCTFKDIEAVDLN
                     VVENLLKENKDITHISMVHCETTTGRLNPIQEVGKLAKEYNKIYIVDAMSSFGGIEID
                     VEDFNIDFLVSSSNKCIQGVPGFGFIIANKEKLSKCKGIAKSLSLDVYAQWETMEKNN
                     GKWRFTSPTHVVRAFYQALLELEEEGSVEKRYARYKENQFTIASRLKSLGFDTLVNDN
                     AQSPVITTFLYPKNAKFEFMEFYTYLKDNGFVIYPGKLTDIDTFRIGSIGEVYPTDME
                     RLADVIEKFINR"
     gene            complement(13741..14526)
                     /locus_tag="PC494_002461"
     CDS             complement(13741..14526)
                     /locus_tag="PC494_002461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HDF3912953.1"
                     /translation="MSLNSIDRKKEILKLLDSKGKVNTKELVKRLEVSSETIRRYLEE
                     LENENKLKKVYGGAIKINYGVIEPEHIKRNNTNLDKKQSIAKYAAKFVNDNESIIIDE
                     GTTNLQIVDYIISVNNLKIITNSYPVLSKLISYENQGLFDGEVIFIGGKVNLKHQRTA
                     CPMSIDTMKNLYVDKAFISSEGILDSFGISSIDQNKALLSKEYIKNSKESFVLCDSSK
                     IGIASMYKIADLEELDFVICDVEPPNEWKDKLNEINITWIEAK"
     gene            complement(14743..14973)
                     /gene="dltC"
                     /locus_tag="PC494_002462"
     CDS             complement(14743..14973)
                     /gene="dltC"
                     /locus_tag="PC494_002462"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HDF3912954.1"
                     /translation="MQETVIEIFEDVLGTDEIREDLDLNLFETELLDSLAIIEVLLEI
                     ENRLGIELQPTDLERKDMSTVNNLVKFLETRK"
     gene            complement(14992..16140)
                     /gene="dltB"
                     /locus_tag="PC494_002463"
     CDS             complement(14992..16140)
                     /gene="dltB"
                     /locus_tag="PC494_002463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HDF3912955.1"
                     /translation="MIFSQYGDYFYLYILLLTSIPAVILGLMGKNIKYYGMLASLFMI
                     FLIVGIDVQLKYLVIFIILEVIIVKGYEYVRRKTKNKYIYWGFLFASMLPIIINKISP
                     VTSFGIIGFIGISYLNFRTIQMVIEIYDGAIKEVKISKMLYFMLFFPTLSSGPIDRSR
                     RFEQDLEKQISRKEYIEEYLLPGIKNIVMGVGYKFVIAFLINTYWVSRIPKDMSFINI
                     LSYMYAYSLYLFFDFAGYSLFAIGTGYIFGIQVPINFDKPFISKDMKEFWTRWHISLS
                     RWFGDYIFSRFVMSSMRKKRFKKRTTAAHVAQMITMITMGFWHGLTWCYVAYGVYQGL
                     ALVLTDIYQRKSKFYKKHKKDKWFERVQIFITFHIVCFGLLIFSGYLA"
     gene            complement(16140..17654)
                     /locus_tag="PC494_002464"
     CDS             complement(16140..17654)
                     /locus_tag="PC494_002464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase"
                     /protein_id="HDF3912956.1"
                     /translation="MKIIEGIKKYSNTDRTALMCNGDKLSYKDLNEYSDAISVFLKDV
                     YKEEDTPIVIYGNKENMIMACMIGALKSGRAYVPLDISFPIDRVFEVTKEIKPKVLFN
                     FSDERNFGDINVIDMDKLNDIINEYQGKSLDKENWVKDDENAYILFTSGSTGKPKGVQ
                     ISSNNLDSFSDWISPYLNIDGSEKVIMNQPAYSFDLSVTTIYPGLIHGATLFSISKDV
                     LADYRELFRQFSISDIAVWVSTPSFAGVCITEKEFNSKMLPNLESMIFIGEALSKNLT
                     KELMSRFPNTRIINGYGPTEATVGVSVNDMTQKAIDDEKSLPVGYPMSNCKIKILDED
                     GNELKENEKGEIIIIGPSVSKGYFNNKEKTDEVFFYDEIDGVKWRAYKTGDMGYLLDG
                     NIYYCGRKDFQIKLNGFRIEIEDIENNLRKVHNVKNAVVLPVYKDEKIAYLKGIVELN
                     EKNDLSNIKNGMIIKKELGKYIPSYMIPRNISIISEFPTNINGKIDRKKLMEEI"
     gene            complement(17775..18965)
                     /gene="dltD"
                     /locus_tag="PC494_002465"
     CDS             complement(17775..18965)
                     /gene="dltD"
                     /locus_tag="PC494_002465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HDF3912957.1"
                     /translation="MRKLIYFITPFIIGVVFLFGLDKFLDSKTDELLREKNLLPIMDD
                     TLSDIKDKGVTANNHFLREKDIMILGSSELSNSTKQHPKYYFNTNRSKNKVFAIGRAY
                     TQTLQDAAILGSMNPNIDNKKVVLLISMQWFMEKDGVTSHHYQSRFSPIQFYRFLDNP
                     KISKQNKIEYAKKSSKLLWGSDEYKAEALYAKLYEPKTFPEKAEKVLLEPYFQGRKYC
                     IALKEKGILYKRLIKLDKKRATKRKRPINWSYERKKAIEDAKKRVGKNPLNIDKYYYK
                     EHFKDGIEQYKGRDKDVNLLTSKEFENYKLMLNVCTDLGIKPVVVLIPSMDKFYNLTG
                     ISEKERNQYYDKAQKIAESKGFEVLNLKDKGSDKYYLRDVMHLGTKGWVDVCERLFKI
                     FKEQ"
     gene            complement(19253..20272)
                     /locus_tag="PC494_002466"
     CDS             complement(19253..20272)
                     /locus_tag="PC494_002466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HDF3912958.1"
                     /translation="MMGKIRFGIVGTSNIANIFLRAASRVKDFELVAVYSRNLEKARE
                     FGTLYGASIFFDDLEQMAKSKDIDAVYIASPNALHSKQTITCLKHKKHVLCEKSLASN
                     LKEVKSMIKTAKDNNVLLMEAMRITCVPNFKAVKENLYKIGKIRRFFGSYCQYSSRYD
                     KYKNGIIENAFKKELSNGALMDIGVYCIHPMVNLFGAPKTVKAVSHILQTGVDGEGSA
                     VFQYDDMDAIIQYSKVADSYIPSEIQGEEGSIIIEKLNLFEKAIIKYRDGREEDISIP
                     KEKAEEKPREIEGMYYELVEFISLINNNKIESNINSHENSIIVMEIMDEIRRQSSIVY
                     PADSI"
     gene            complement(20448..20987)
                     /locus_tag="PC494_002467"
     CDS             complement(20448..20987)
                     /locus_tag="PC494_002467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative ABC transporter permease"
                     /protein_id="HDF3912959.1"
                     /translation="MDNVGSLLYFLFNFFLYGFIGWIIENLYSYYKQGHFQEDGFLNG
                     PFKPMYAIAMSIIIEVSRFIDPNNIFALLLLCLVVPTVVEYITGILMKVYFNKVYWDY
                     SDYKYNSRGIVCLKFSVYWTILTFIGVRYFQVYIVDSLYSLIIPYWPIVVTILLVTLF
                     VDEILTIKFLRGNKDIVER"
     gene            complement(21088..21768)
                     /locus_tag="PC494_002468"
     CDS             complement(21088..21768)
                     /locus_tag="PC494_002468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HDF3912960.1"
                     /translation="MQNVEGIIFDMDGVLFDSERISLEFWMETFEKYGYTMTKEIYTS
                     VMGRNRKGIIEGLTDIYDSSVPIIDLYDEKTKNMIEFMERKGAPIKLGVNELISFLKE
                     NGYKMAVATSTKRERAVKRLAKANLKDYFDAIVCGDDVVNSKPNPEIFLKAAKKINVN
                     PKNCIVIEDSPMGVEAAYNGGIRCINVPDLKEPDEQIKSQSHKILENLLEVREYLKSL
                     NSKECHNL"
     gene            complement(21797..23086)
                     /locus_tag="PC494_002469"
     CDS             complement(21797..23086)
                     /locus_tag="PC494_002469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HDF3912961.1"
                     /translation="MRELLKVTLIVMLVLINAFFVACEFAMVKLRSSRIDTMITEGNN
                     NAKRCKIIKDNLNSYLSACQLGITLCSLALGWMGESTVKELILPIVSVFNLSESIIYT
                     ISISISFLIITMMEVVIGELVPKALALYNTEKIMLSTSFLLVGFYKLTYPIIYFFNLS
                     TDLFLKPFGYSQADEVDEPHTGDEIRLLVEESYKSGLIDESEQRLVDNIFEFEEKKIR
                     EIMVPRTDMVCIYESDSEEKILAILKEEGVTRYPVCRKNKDDILGFVHIRDLYNQKIN
                     ENKIELEEILRDIIYISENLTIDKALERIRKEKLQLAIVVDEYGGTSGVVTIEDILEE
                     IVGEIQDEFDKEETHIKKIGAGSYLVDGTESINYINKYFGLDIEHDGFDSIGGWISYM
                     LGSNIKVNQSVTFENYNFTILELDKLRVVKLIIKSVI"
BASE COUNT         7613 a         4009 c         2458 g         9303 t
ORIGIN      
        1 aagtatcact tttatattaa ttatttttta ttacctctat attattgtat tgcttaaaaa
       61 tacataattt aactcttatt taataacaga aactcccata tatggtctta aaacttcagg
      121 aacaaccaca gaaccatctt cttgttgata attttctaat atagctgcaa cacttcttcc
      181 aatagctaac ccagagccat ttaatgtgtg tacatattca gctttagaat ctttatctct
      241 tttaaatctt attcctgctc ttctagcttg gaaatcttcg cagtttgaac aagatgaaat
      301 ctcaacatac ctattgtaac ttggcatcca aacttctaca tcatatttaa aagaagccgt
      361 aaatcctaaa tcacctgtac atatctttac taccctataa ggcagattca ataattgtag
      421 catagtttcc gcattgttag taagcttttc taactcattg taagattctt ctggtgcaac
      481 tattttaacc atttctactt tgttaaactg atgctgtctt actaaacctc ttgtatctct
      541 tccagcagaa ccagcttctg acctaaaaca tggagtataa gctgtataat ttatcggtaa
      601 ttgttcaaat ttaagtattt cattagcatg tatattagtt aaaggaactt ctgatgttgg
      661 aatcataaaa tagtccagac cttctatttt aaacatatct tcttcaaact taggtaactg
      721 tcctgtacct aaaaaactat ttctatttgc cataaatggt ggaataactt ctgtatatcc
      781 atttactttt gtattcgtgt ctaagtaaaa atttaataat gctctctcta atctagcacc
      841 taaacctttg taaagagtaa atcttgaacc agttatttta ctagctgttt caaaatcaag
      901 tatacctaat tctgttccaa tttcccaatg agccttagat tcaaaatcaa aggtagtagt
      961 ctttccccaa gttcttactt caacattatc ttcatcagtt tcaccttgtg gtacttctgg
     1021 atgtggtaca tttggtattc tcattaatag gtattccatc ttatcttcta cttctttaag
     1081 attttggtct attaccttaa ttttatcaga taactctttt agtttaatct tttcattttc
     1141 tacatcttta ccttctttta taagatttgg tatattttta gatgctgtat ttaattcatt
     1201 tttcataact tcaacttctt gaagaatctt tcttctttca tcatctaact taactacttc
     1261 atcaaggtta aagtcttttt cgccccttct ttccattgct ttttttatac aatctaaatt
     1321 ttctcttatt ctttttatat caagcatttt ttcctcctca gtacttaaga ttggatttat
     1381 ctcttaatct caaataactt agataatata ctttatgctt gaggttaaga aacctttttc
     1441 tttatccgaa cctgttattt ttattttatt tatattttac tcactttttt gcccattgtc
     1501 aaattatatt taattaaata aatgaaattt aattttagga gaatattgct agatttaact
     1561 tcattataat tatatctatt ttgctaatca attatctatt ttgacttttt ctttatcaat
     1621 cttatatagt tattaacttt tatataaatt tttttatatt ataacatagt cctatatatc
     1681 tattatttgg atagaattat tttttaaatt agaattattt taatgaatga ttcaagtaat
     1741 aggtatgaaa ttgaatcttt tagaactgct tacaaaaaat actcaaagaa aaatagtaat
     1801 tttctcagat tcacaatata ttttatatga aatgttataa ggtaatctat ttaataaatt
     1861 taaatttgct attatagatt tagttccaaa gtcttactgc aaagtaatat acatagtttt
     1921 ttaataaact aataagtgca attaataact acttaattgt ttaatatagt acatagataa
     1981 ctttaataaa tctacagtta tttaaaaagg tagaatcaat aaaattatac ttataaatct
     2041 tcaatacaat aattaaaatt taataaaaat ataattgttg atttaactgt aatcttattt
     2101 aattctacct aacttattat ataaaactat tttttataga ttataaaata tctaactttc
     2161 atctacttca aagaatacaa tacttctcct tctcttatag tctgcaatac tttaatatct
     2221 tttattttca tagggtcgat tgtaagtggg ttttcatcta atattatcaa attagctaat
     2281 ttcccttctt taattgaacc ttttttatct tcttcaaaat attgatatgc tgcatttata
     2341 gtaacaccct ttaaagcatc taatgggctt atcttttcat tttctcctat ttgtatacct
     2401 ttttttgtaa ttctattgac agcacaccat actgtttcca gcatattagg tgctattact
     2461 ggtgtatcct gatgaagagt gtaaattaat cccttttcta tagttgtttt aagtgggcta
     2521 atcttaaacg ctctatcttc tccaaggttt ttgatatgaa tatcacccca ataatatgtg
     2581 tgagctacaa agtatgaagg tatcatattt attactttca tatcatcaat ctggtcttct
     2641 cttactgttt gagcatgtat cataactggt cttatatgat tttcactact ttgctctttt
     2701 aagtttaaaa ctttctcaaa cgcatctatc aactggtctg ctgctgcatc tccattacaa
     2761 tgagttaaga gttgcatctt ttcttttagt gaaatatcta taaacttttc tacttcttca
     2821 tctttgtata taggatatcc acaataacca tcatctgaat tttcatatgg tctactcaac
     2881 catgctgtct taccttgtgg agaaccatct aagaaaatct tataacctcc tattttaaat
     2941 ctatttatat atttttttat aaactcccta ttattatctg ctacagactt actttttttc
     3001 aaatttacat atcctacaac atccattttt aatttatttt gatttgccat tgcttttaaa
     3061 atgttaaatt gattttcttc cattaaacct tcttgagctg ttgtaatacc ataacttaga
     3121 tatatgttct gtgctttttc aattgaatta aaaatctcat ttgatgatgg ttgttttatt
     3181 ttagatgcta cattaaaaaa tgcattttct tctaaatatc catttggttc ttcactgcct
     3241 tctactctac ctatatgtcc accttctggg tcacgtgttt cattggtaac accaagctgt
     3301 tttaacccca atgtatttgc aactcccata tgaccagaag catgtgaaat tagtattgga
     3361 ttttctgaag atgcactatc gagtacactc ttatctggat gcttattttc ttctaaaaaa
     3421 ttattatcat atgaaaatcc aattatccag tctccttttt ttatattatt cgactctttg
     3481 aaatcctgta ttttttttac tatgtcttta aaactggttg catcttctaa aggaactagc
     3541 tttagagtag tagcaaaagc tatcaagtga ctatgtgaat ctataaaaga tggcatcaat
     3601 gtcttacctt gtaaatctat aatttctgta tctttatttt tcaaagcaaa tacttcttct
     3661 tttgttccta tcttttttat tattttgtct tttataagaa tagcatctcc acatattgaa
     3721 tcttccattg tgatgatatt tccattgtaa taaatttttt ctttcataaa attctcctta
     3781 cgttgtctac tttaataaat ttttttcatt attttctgct taattatatt atcttcttta
     3841 taaacttttt ctttagagtt taatcatata aaagttttat ttttaattat tgtttgccaa
     3901 gaagtaaata ctattcattg taaataagac aaattaatag gctttatact aattgaaaaa
     3961 atattataag ttgttaaatt taaatatcta aactcaatta tatctgtaca attgtaattt
     4021 tttaaatcat gatgtattat tttaaatata cagttacatt attattcaca atataagtat
     4081 cttagttctc aaataacatc tcatgtaatc tattcaatgc aaaaaattta aatatttttt
     4141 aggaggtttt ttatgagcaa ggaaaataaa aatgtaagaa ttgctgttgt ccaggcgtca
     4201 ccagtcataa tggatttaga aaaaactgtt gaaaaagcat taggattaat taaagaagct
     4261 ggtagaaaag gggcaaatat cgtagttttc cctgaagcat tcatacctgc atatccaaga
     4321 ggtctttcat ttggatttgt tgttggaagt agaacaatgg aaggtagaga agattggaaa
     4381 agatactatg ataattctgt accagttcct agtgctacaa cagatttatt aggaaaagca
     4441 gcacaagaag caggagtata tctatcaatg ggtataacag aaagagatgg taatgatata
     4501 aattgtaccc tttattgcac aaacttattt ttctctccag aaggtaagct aattggtaaa
     4561 cacagaaaac ttaaacctac aggaacagaa agatgtattt ggggagaagg agatggaagt
     4621 actcttacag tagttgatac tccatatgga aaaatgggtt cgttgatttg ttgggaaaat
     4681 tatatgccat tagctagaac agctctttat gctaagggtg taaaacttta catagcccct
     4741 actgcagatt caagagaaga gtggcaagca actatgaagc atattgcttt agaaggaaga
     4801 tgttttgtaa ttggatgcaa tcaatatgtt gaaaaaaata tgtatccaac tgaccttaac
     4861 tactataaag agctagatgc agaaccagaa attatgtgtc caggaggaag ttgtatagtt
     4921 gacccttttg gaaaatatgt agcaggtcct attttcaata aagaagaaat gctaatagct
     4981 gatttagacc tagaaaaaat agtacttagt agactagatt ttgattcaga aggtcactat
     5041 tcaagaccag atgtatttga attaattgtt catgaataat ctttttacac aaacatctac
     5101 ataaatcttt ttacataaaa aaatgagata ctcataagta aatttcaagt atctcatttt
     5161 tgcttaaaac ctataatcct aattataaat ttattcacct atattttttc taaatcaact
     5221 actgttcttc caacatgttt tcctgccatt attgaatcta tactatcatt taactcttcc
     5281 aatgatacta catttaccat atcatctaaa tcatctaatt tccattcatt tgataataaa
     5341 tcccatattt ttaatcttaa gttcattggg caatccacag aatctatacc atataaagta
     5401 attcccttta agataaatgg atatactgaa cttgtaaaat caactcctcc tgcattacca
     5461 caagttgtta ctgctccaca ataattagtt gtctttattg ctgttgctag agtatttcct
     5521 cctactgtat ctattactcc agcccatctt ggtctaagca gaggtcttcc tgagttatca
     5581 tccacttctg acctatgtat aacatcttta acacctaagt ttagtaatac ttctttttgt
     5641 tcttctaatt ttcctgttga aactacaact gaataaccta atttaatcaa tattttagtt
     5701 gcaattacag caactcctcc agtaccacca gtgactaata catctcccat attcttgtct
     5761 acagaatcta taaatttata cacagataaa gctgctgtaa accctgctgt accataatcc
     5821 attgcttctt ttagtgaaag atttttagga agtttaacta cccaactaga aggaactctt
     5881 atgtattctg aaaaaccacc agaagtattc attcccaagt cataacctgt tactaaaact
     5941 tcttctccaa ttttaaaatc atcacaacta ctagattcta ctataccaga tgcatcaatt
     6001 cctggtgtat gaggatactt tctcgtaaca cccttattac catttgcaga aagtgcatcc
     6061 ttgtaattta aagaagaata ttttactttt attaaaactt cgccttctgg caatgtatcc
     6121 acttctcttt caactatatt tcttctaaaa tttccttctt cttctgtaat atatagtgat
     6181 ttaaattttt tattcataaa tttcctccca atacatttag ttttatgtta aactaattat
     6241 agtttataaa tagttttatg tcaaactaat ttaaatagat taaagattgg agaataattt
     6301 atggaagata aatatattgt acatttcata agtaaaacaa aggctagtat gattaaattc
     6361 attgaaaata aactcagtaa aaatggttta ggtgagttaa tacctactca tggaaatatt
     6421 ttaactgcac tttatgaaaa taatggaata cttacaatga aagaaattgc agctaaaata
     6481 ggaaaagata aatccactgt tacagtgttg gttaataaac ttataaacct aggatattta
     6541 gaaagacaaa aatgtacaaa tgacaaacgt atcacgtata taaagcttac aaaaaaggca
     6601 ctgcttatag aagatacttt taatagcatc tcaacacaag ttaaagagac ggcataccat
     6661 aatattacag aaaatgaaaa acaagaattt cttagaattt taaaaaaaat taatgataat
     6721 tttaaaaatg ctgactaaat tgagcataat tatatctcct attggaataa taaataaaaa
     6781 gaatcaaata ttgtaaaaat ttattgtgat agagaggtag aatatgaatt taaaagatag
     6841 taaaactaaa gaaaatttat taagagcttt tgcaggtgag agtcaagcta gaaatagata
     6901 caatatttct gcatctgtag caaaaaaaga aggattatat ataatagagt ctttatttaa
     6961 ttacactgct gaccaagaaa aatcacatgc aaaacaattc ttttctaaat taaaagaatt
     7021 tgctggtgaa aatataagta tatcaggagc ataccctgta gatttatatg acaagacagc
     7081 acaacacctt aaagctgcac aacataatga gcttcaagag tgggatgatg tatataaaaa
     7141 ctttggaaaa acagcacgtg aagaaggatt tgaatctata gctaagttat ttgaaaatat
     7201 agctgaaata gaaaaagttc atggtgatag atttggtaga tatgctactg atttagaaga
     7261 aggtacttta ttcagaagaa atgaagatat acaatggata tgtacacatt gtggccatat
     7321 acatataggt aaagaagctc ctaaagcttg tcctgtatgt cttcatccac aaggatattt
     7381 cttagatttt aaaaactcat tatttgaata aactaaggta atcattgtat ttaaacaatt
     7441 tactatattt atatcaagta tttttataaa tactgtatta tcttaataac aataaaatga
     7501 accattgata ttactataag tagaaaatgt agtttaaata caatttatag tagttcatca
     7561 tggttcattt tattgtttac taatccctat aacttactta aatctatctt taacttttac
     7621 atactcacat aaatcctcat ctctaaacta aatatttaaa taaagtgtat tttaagtaga
     7681 ttattataat acattatata agataataca ctatgataac tttatactta tatcatttat
     7741 ttcttttgtc aagtcaacct caataatctt aactacatct ttttcaaact ttactttttt
     7801 ataatccaga catcctacta cgaatggaac tccaaacttt ctaaacaaat aaatctttcc
     7861 actttcattg tatattgatg taaaattttc ttctattata ttcactatca attttaactc
     7921 ttcaaaagtt attatagatt taactaaaaa cttctctatt atgctcaata taagcagttc
     7981 ttttttacct atgctttgtt cttttttata taaattttga aatatttctt tggtataatt
     8041 acatataact tctttactga gaataaaatc aatgtcaaat tctttattaa tatccttttt
     8101 cataaacata tttgcaatat cctgaacctc ccatgactaa agtcacaggg ttcctgcttc
     8161 atagaatttt gcatactaaa atatgtctta ctaattctcc acaggctatc cccgtgttcc
     8221 tacggttctt acataagtta tttattttga attgttatta gtcttaatcc ttcttttaat
     8281 atatttatac ttgcatttat atctctatcg tgagtttcat tacaactagg acaaatccat
     8341 tctcttatat ttaagtcctt catttcctcg tttttatacc cacatttatt gcatatttgt
     8401 gaacttgcaa agaatttacc tacctttaca atttgtctac catgccaatt agccttgtat
     8461 tttaattgac gaacaaattc tgaccatgac acatcagaaa ttaagcgaga tagtttacga
     8521 tttctaatca tattctttac ttgtaaatct tctatgcaaa taatatcatt ctcttttatt
     8581 aatttagtag atagtttttg tagaaaatca tttctttgat tagctatatg ttcttgaagt
     8641 cttgcaactt ttaatcttgc tttatttcta tttaaactac cgattgtctt tctcgataat
     8701 tctctttgta atttagcaag tttgtttaat gacttcttaa gatacttagg attttctata
     8761 aagtctccac aacttgagat acaaaattct ttaattccta aatctaaacc tatctgatta
     8821 ttagtatttt caaatacttc aatatctaca ttagtacagc ataatgatac ataatatcta
     8881 ccacttggtt ctttagatat agtagcatta agtattctac cttgaggtac ttgtttatcc
     8941 cttaccttaa ccataccaag tttaggtagt tttatatatt gaccacaata cataatgttt
     9001 ccatttgtaa agttagtttt atatgaaaat ctattaattt tctttgattt aaatttagga
     9061 aatcctgctt tttctttaaa gaatttttta tatgcattat ctaaatcttt taaggcgttt
     9121 tgtagtgaaa atttgtcagg ttccttaagc cattttaatt ctttttttaa attggttaaa
     9181 tcagaactac actgtttata agtaaaagtt tctttattgt ttttataaac ttctattctt
     9241 ttagcaagat acttattata tacaaatcta caacatccaa aagttttgtt aattaactct
     9301 tgttgttttt tatttggata cattctaaac ttataagctt tttccactac tgccacctca
     9361 ctttacttgt tttttctgat tattaatata ttttcttatc tgttcttctg tattttctga
     9421 tacagtagca acgaaataac taggattcca aagatgtcct ccccataatt tctttttcaa
     9481 ctgttctcca tgttttttca ttaacagcct tgctgataca ccttttaatg cttttattat
     9541 atctggtata tagtgttgtg gtgaacaatt tattagtaaa tgtatgtgat ctttatcact
     9601 attacattct aatatttgaa atttattatc ttcagctatt ttgtttaata tattaattaa
     9661 atcttcttca atttcatttg ttaatactgg atgtctatat tttacacacc atactatatg
     9721 gtattgtact aaatacacat accctctacc atgagtcact tccatttttc atcacccaac
     9781 ataatattaa catagtaatt acttaaaaca agtattctta aggtttttat atttattttt
     9841 aaataacata cgtaagaaac gcaaatctta acttttatca tttttgaggt tgtcgttcac
     9901 ataagttcgc tactacctat gcagttctct tatgaacttc ttacactttc atgcaagcac
     9961 agactatatc ttatccttcg gcattatccg ttaaggtcta cccacttcca ctaccgatag
    10021 cttgtagtgt acttccctca agaggaatag tcgttgaagt ttttcctatt cggagcttac
    10081 ctgctgattg cccattttaa agtacttagg atttaacctt ataccatcta accaattttt
    10141 tctactttcg taactttcac acttaggttt atttcatcct tatgttttag tttggttagc
    10201 tttaggggtt tccagcaatt caagtagtat tggataggtt ctatcctatc tctacatata
    10261 agtttcccta tatgctgact attttagcta ctaactcatg actaaagtca caagtgtgca
    10321 tagctatttt ttaatcaaga gaagtctctt ctttcataga caatattaac tctattcttt
    10381 ctagtatttt atctcttgga aagaaagtct cttgacctgt aaaagctgat ttttttataa
    10441 accattcctc tggtattatg ttttttcttt tccatctata taattgtcca taagatatat
    10501 tagttttgct caataaatct ttcttagata ttaattcttc catagctctt ctagcccacc
    10561 tttatactgt tttttacagt agaattatct gaaactgata aattatcact gtattcaata
    10621 tttccaacat cataattatc tactagagat atgctttttt tctagcatac gaaatttttt
    10681 gcaataatct ccatgcccct tttttatatt tatactactt gctccaactt cattaaaatt
    10741 agaagttcca tttaaactaa tattaacttc ttcacaattc aaaaatccat tacactccaa
    10801 gattccactt aaattgatat tttcacaatc tatattctca tttgctttta aatatccttc
    10861 tccatgaata atatccgatt ttatacttcc ttctacatta ataattccac tagtatcaat
    10921 ttcaacagaa ttaatatttc ctgtacatct aagaagtccc gatatctcaa cttttgatgc
    10981 cagtatgttt ccttctactt tacttaaacc agatgtaaaa aattcattac attctgttgt
    11041 cccaaaaact tttgctgaac cagaagaatc aaatttacta cattttacac ttccttctat
    11101 tttgcctgtt cctgatatat taacattatc aaaaattcca cctttacatt ttccaacacc
    11161 atcaaatctt agtgaactta attcttcatt cataatgata tcctttcttt accgtatttt
    11221 atctttaaac ctaatataac aaaacattgt tacgttgtca agtatgataa taatacttaa
    11281 taaagcaact atcatttatt ttctataaat aggcataaaa ataataggga aatgctttat
    11341 ttaaactata aatctaattt cttagattgt ggtttaaata aaatatatcc ctattactca
    11401 atgtttatat attcattgta taaacttcta aaatataagt ctttaaattc tactgtcaat
    11461 actttttata cactgtttgt gctatcatct cacacaccta aaggagtagg ctttgcgcac
    11521 tattctgtaa cctacaagac actatcttct tctatctatt gataaatttt tctattacat
    11581 cagctagtct ctccatatca gttggataga cttcacctat gctacctatt ctaaatgtat
    11641 ctatatcagt caatttacct ggatagataa caaatccatt atcttttaaa taagtataaa
    11701 attccataaa ttcaaacttt gcatttttag gatataagaa agttgttatt acaggtgatt
    11761 gagcattatc attcaccaaa gtatcaaagc ctaaagattt taatcttgaa gctattgtaa
    11821 actgattttc tttatatcta gcatatcttt tttcaacaga accttcttct tccaattcta
    11881 ataaagcttg ataaaaagct cttacaacat gtgtaggtga agtaaatctc catttaccat
    11941 tatttttctc catagtctcc cattgcgcat acacatcaag agataatgat ttagctatac
    12001 ctttacattt agataatttc tctttattag ctattataaa accaaatcca ggtactcctt
    12061 gtatacattt gttagaacta ctaactaaaa aatctatatt aaaatcttca acatcaatct
    12121 caattccccc aaaactactc atagcatcaa ctatataaat tttgttatat tcttttgcaa
    12181 gtttccctac ctcttgtata ggatttaatc tacctgtagt agtttcacag tgaaccattg
    12241 atatatgtgt tatatccttg ttttctttta ataaattttc tactacattt aaatccactg
    12301 cttctatatc tttaaatgtg cagtcaacaa attgtatgtt aagataatta catatatctt
    12361 tcattctctt tccatatgct ccatttgcaa ttacaagaag tttaccatct tttgaaatag
    12421 tacttcctat tatagcttct actgaaaaag tcccacttcc ttgcattaat acacttgtgt
    12481 atttatctgt attttgggtt gctagagata ctaatcttct tctaacatct tgtactaggt
    12541 tattatattc aacatcccaa gtacaccaat cttttaacat agatgctctt actgatttag
    12601 tagtagatag tggtcctggt gtaagtaata tgtaatcatt ttctggtaca aaatctgatt
    12661 taatagtttc attctctatt tttattagta tatcttctaa ctcagccata gtttctatta
    12721 caaaatgtgc acctgcctct ttaaatttct ttgaaactat actcatctta gcttttaatt
    12781 cttccttatc catgttctct acttcttctt gtgtaagccc taactcactt gaacctttta
    12841 ttacagcaac actccacatt cctgcattta cgccttcttt tacatcactt attgtatctc
    12901 ctacttttac catagaactc ataggagaca cccctaaagc ttcagcattt ttatagcaca
    12961 tccaaggata cggtcttcct tgagatactt ctgatggtgt tacaagaaaa tcgggtgagt
    13021 atcccttctt tgctgcattt ggttcaacta tgttcatcat ctctcttgta taacccgttg
    13081 tagaacctat ttttaatcca ttttttctca acttttcaat agtttcaaca acatgaggaa
    13141 ttggagtcgt atactcttct aatgtctcaa ataacattgg ctcaaattca gcataaagtt
    13201 catttacatc atcttcagtt ggcactttac caaacttatc tgaccaaata ttctttattc
    13261 tatccatttc acacatttct cttatatggt ctatttttaa ttttcccata ggttttcttg
    13321 cttcttccat tgttacatct atacctcttc ttttaaatat ctctataaat acattaagag
    13381 gtgcaaaaca tccataatct actgttgttc cagcccaatc gaatactact gcttttattt
    13441 tttctccata tatctttttc atatttatag cctccataga ttctttttag aatttttgtg
    13501 tttttaattg tttttacttt taaagtataa ctttcatatg ttaattatac atcatattta
    13561 ggttaaatat atattaaatt tctgttttta gttgtattta gttgttttta ttttgtatca
    13621 tattcccata aaatcctaag ttacaatcta aaatttactt tctaatctta atctatgaac
    13681 tgactatatt ttatgaattt agttgtattg agcatagttg tattatataa aactaagggt
    13741 ttattttgct tctatccatg ttatatttat ctcatttaac ttatccttcc attcattcgg
    13801 aggttctaca tcacaaataa caaaatctaa ttcctctaaa tctgctatct tatacatact
    13861 agcaattcct attttagaac tatcacataa tacaaaactt tcctttgaat tttttatata
    13921 ttcttttgac aacaatgcct tattttggtc tatactacta attccaaaac tatcaagtat
    13981 accttcacta gatataaaag ctttatctac gtataagttt ttcatagtat ctattgacat
    14041 tggacatgct gtcctttggt gttttaaatt tacttttcca ccaataaata taacttctcc
    14101 atcaaacaaa ccttgattct cataagaaat caattttgat agaactggat aagagtttgt
    14161 aataattttt aaattgttta cagatattat ataatctaca atctgcaaat tggtagtacc
    14221 ttcatctatg ataattgact cattgtcatt tacaaactta gctgcatatt tagcaatact
    14281 ttgcttttta tctaggttag tattgtttct ctttatatgt tctggttcaa tcactccata
    14341 atttattttt atagcaccac catatacctt ttttaattta ttttcatttt ctaattcttc
    14401 caaatatctt cttattgttt ctgatgatac ttctaatctt tttactaatt ctttagtgtt
    14461 taccttccct tttgaatcta ataatttaag tatttctttt tttctatcta tcgaatttaa
    14521 agacattcat tttcctccta aatataatat atttttctcc tataatatta caatgatacc
    14581 taagatttat gaaatcatat ttatgtatta aattttttac ttaattaaag ttattttcaa
    14641 aagactttgt attatcatta aaaaagtcca tcaaatatta gtatcagatg gactttgtaa
    14701 aattttattt tataaattaa tatttaaagt ctaactacta atttattttc ttgtctccaa
    14761 gaattttact aaattattta cagtagacat atcttttctc tctaaatcag ttggttgaag
    14821 ctctatccct aatctatttt caatttcaag taaaacttca attatagcta atgagtctaa
    14881 aagttccgtc tcaaataaat taaggtctaa atcttctctt atctcatcag tccctaatac
    14941 atcttcaaat atttctataa ctgtttcttg cataaatttt cctccttaaa attaagctaa
    15001 ataacctgag aatatcagca atccaaaaca cacaatatgg aatgtaatga aaatctgcac
    15061 tctctcgaac catttatctt ttttatgttt tttataaaat ttagattttc gctgatatat
    15121 atcagttaac acaagtgcca atccttggta tacaccataa gcaacataac accaagttag
    15181 accatgccaa aatcccattg ttatcatggt tatcatctga gccacatgag cagcagtagt
    15241 ccttttctta aatcttttct ttctcattga tgacataaca aatctagaaa aaatataatc
    15301 tccaaaccat cttgaaagac ttatatgcca tcttgtccag aactctttca tatctttgct
    15361 gataaatggc ttgtcaaagt ttataggtac ttgtattcca aatatgtacc ctgtacctat
    15421 agcaaataaa ctatatcccg caaaatcaaa gaacaggtat aaactatatg cgtacatata
    15481 acttaaaata tttataaaac tcatatcttt aggtattctt gatacccaat atgtatttat
    15541 caaaaatgct ataacaaact tataacctac tcccatgaca atatttttta ttcctggcag
    15601 taagtattct tctatatact cttttctaga gatttgtttt tccaagtcct gttcaaatct
    15661 tcttgaccta tcaataggtc cagaacttaa agttggaaaa aataacataa aataaagcat
    15721 ctttgaaatt ttaacttctt ttatagctcc atcataaatt tcaataacca tttgtatagt
    15781 tctgaaattt aagtatgata ttccaataaa tccaattatt ccaaaagaag taactggaga
    15841 tattttattt attattattg ggagcattga tgcaaacaag aatccccaat atatgtattt
    15901 atttttagtt tttcttctta catattcata tcctttaact attattactt caagaataat
    15961 aaatattacc aagtacttta gttggacatc aattcctact attaagaata tcataaacaa
    16021 acttgccaac ataccataat actttatatt cttgcccatt agacctaaaa ttactgctgg
    16081 tattgatgtt aataataata tataaagata aaaataatct ccatattgtg aaaaaatcat
    16141 taaatttcct ccataagttt ctttctgtct attttaccat tgatatttgt tggaaactca
    16201 gagattattg aaatatttct tggaatcata tatgaaggta tatactttcc aagttccttt
    16261 tttattatca tcccattttt aatattactt aaatcattct tttcatttaa ctcaacaata
    16321 ccttttaagt aagcaatttt ttcgtcctta tatactggta aaactactgc attttttaca
    16381 ttatgtactt ttctcaaatt attttctata tcttctattt caattctaaa tccatttaat
    16441 ttaatctgaa aatcttttct tccacaataa tatatatttc catctaaaag atatcccata
    16501 tctccagttt tataagctct ccactttaca ccatctattt catcatagaa aaatacttca
    16561 tcagtctttt ctttattatt gaagtaacct ttagaaactg atggtccaat tattataatt
    16621 tcaccctttt cattttcttt aagctcattt ccatcttcat caagtatttt tattttacaa
    16681 tttgacatag ggtatccaac tggaagactt ttttcatcat ctatagcctt ttgagtcata
    16741 tcatttacac ttacaccaac agtagcctcg gttggtccat atccattgat aattcttgtg
    16801 tttggaaatc tactcataag ttctttagta agattttttg aaagtgcttc tcctatgaat
    16861 atcattgact caaggttagg aagcatttta ctattaaact ctttttcagt tatacatact
    16921 cctgcaaaag aaggagttga gacccataca gctatatctg agatactaaa ttgtctaaat
    16981 agttctctat agtctgctaa tacatctttt gatattgaaa ataatgtagc tccatggata
    17041 agaccagggt atattgttgt aactgaaagg tcaaaagaat atgctggttg gttcattatt
    17101 actttttcac ttccatctat gtttagatat gggcttatcc aatctgaaaa gctatctaaa
    17161 ttgtttgaac ttatttgaac cccttttggc tttcctgtac ttcctgaagt aaatagtata
    17221 tatgcatttt catcatcttt tacccagttt tctttatcta atgattttcc ctgatattca
    17281 tttattatat catttaattt atccatatca attacattga tatctccaaa atttctttca
    17341 tcactaaagt taaataatac ctttggtttt atctctttag tgacttcaaa aactctatca
    17401 attggaaaac taatatcaag aggcacatac gctctacctg attttaaagc tcctatcata
    17461 catgccatta tcatgttttc tttatttcca taaattacta taggagtatc ttcttctttg
    17521 tatacatcct ttagaaatac tgatatagca tctgaatatt catttaaatc tttataagaa
    17581 agtttatctc cattacacat tagtgctgtt ctatctgtat ttgaatattt ttttattcct
    17641 tcaataattt tcatataaga atgctccttt aaaatccgtt ataaataaat ggcaattctt
    17701 taaatggagt aaatgttaga actcctatcg ccaatattat aaccatagtt aaacaaatac
    17761 tagttaacaa atctttattg ttctttaaat attttaaata atctctcaca gacatctacc
    17821 catcctttcg taccaagatg cattacatcc cttaaataat acttatctga ccctttatct
    17881 ttaaggttta gaacttcaaa gcctttgctt tctgctattt tttgcgcttt atcgtagtac
    17941 tgatttcttt ctttttcaga aataccagtc aaattataga atttatccat acttgggatt
    18001 aatacaacaa ctggcttaat acctaagtca gtacatacat ttagcatcag tttataattt
    18061 tcaaactcct tagatgttaa taaatttaca tctttgtctc ttcctttgta ttgctctata
    18121 ccatctttaa aatgctcttt ataatagtac ttatcaatat ttagtggatt tttaccaact
    18181 ctttttttag catcttcaat ggctttcttt ctctcatatg accaatttat tggtcttttt
    18241 ctttttgttg ctctcttttt atctagctta attaatcgtt tataaagaat acccttttct
    18301 ttaagagcta tacaatactt tcttccttga aaataaggct ctaaaagcac cttttcagct
    18361 ttttcaggaa atgtcttagg ctcatatagc ttagcatata atgcttctgc tttatactcg
    18421 tcacttcccc ataataactt acttgatttt tttgcatatt caatcttatt ttgtttagat
    18481 atttttggat tatctaaaaa tcgataaaat tgtattggtg aaaatctaga ctgataatgg
    18541 tgacttgtga ctccgtcttt ttccataaac cattgcatag aaattaacaa gacaactttc
    18601 ttattatcaa tattaggatt catacttcct aatattgcag catcttgtaa tgtctgagta
    18661 taggctctcc caattgcaaa caccttattt ttactcctat ttgtattaaa atagtacttt
    18721 ggatgttgtt ttgttgaatt actaagttct gatgacccca aaatcataat atccttttct
    18781 cttaaaaaat gattatttgc tgtaacccct ttatctttta tatcacttaa agtatcatcc
    18841 ataattggaa gtagattttt ctccctcaaa agttcatcag ttttagaatc aagaaatttg
    18901 tctaacccaa ataaaaatac tacgcctatt ataaaaggtg taataaagta tatcaatttt
    18961 ctcatatttt ctctcctcta aaaatattca aatttatgtt attattaatc atattagttt
    19021 tgatatgtat attcaactac aaaattgtaa taaaatcgtc aaaacttttt ttgatactgt
    19081 tacaaaattg taaaaaaaaa gaaaaaaacg ccaaaaataa atttcttttt agcacttttt
    19141 catacttata atttgacatt ttaacacttg gttaagtata caccttacct taacttaaaa
    19201 ttaaatttat ttaagaatat atattataaa ttcttatatt ttctaatata aactatatac
    19261 tatcagctgg ataaacaata ctactttgtc ttcttatctc atccataatt tccattacta
    19321 ttattgaatt ttcatgagaa tttatatttg attctatttt attgttattt ataagactta
    19381 taaactctac aagttcataa tacattcctt ctatttctct aggcttttcc tctgcttttt
    19441 cttttggaat agatatatct tcttctcttc catctctgta tttaataata gctttttcaa
    19501 atagattaag cttttcaatt attatacttc cctcttctcc ttgtatttca gatggtatat
    19561 aagaatcagc tactttagaa tactgaatta tcgcatccat atcatcatat tgaaatacag
    19621 ctgaaccttc tccatccact ccagtttgaa gtatatgaga aactgccttt acagtttttg
    19681 gagcaccaaa taaattcacc ataggatgta tacaatacac tcctatatcc attaaagctc
    19741 catttgacaa ctctttttta aaggcatttt ctataattcc atttttatat ttatcatatc
    19801 ttgaagaata ctgacaatag cttccaaaaa atcttcttat tttccctatt ttatataagt
    19861 tttctttaac tgctttaaag tttggaacac atgtaattct catagcttcc ataagcaata
    19921 cattattatc tttggctgtt tttatcattg atttgacttc ttttaaatta gatgctaacg
    19981 acttttcaca aagcacatgt tttttgtgtt ttaaacaagt aatggtttgc tttgaatgta
    20041 atgcatttgg agaagctatg tatacagcat ctatatcctt cgatttagcc atttgttcta
    20101 aatcatcaaa aaaaatactt gctccatata gagttccaaa ttctctagct ttttctaaat
    20161 ttctagaata tacagcaacc aattcaaagt ctttaaccct agatgcagct cttagaaata
    20221 tatttgctat attgcttgtc ccaacaatac caaatcttat tttacccatc ataaatcact
    20281 ccccattttc tacactttat tttaatttta ataaaaaact ttacaactta tagatatatt
    20341 ataaaataat tttatcaaat aaaaaagaaa gctaatttta aatgatttca ccattttaac
    20401 atagctttct tttaactaca atctaaattc aacttatatt tttaaagtta tctttctact
    20461 atatctttat ttcccctcaa aaattttata gtaagaattt catccacaaa caatgttact
    20521 aaaagtatag ttacaacaat tggccaataa ggtattataa gactatataa actatcaact
    20581 atatacactt gaaaatatct aactccaata aatgtcaata tagtccaata tacagaaaac
    20641 tttagacata ctattcctct actattgtac ttataatctg aataatccca atagacctta
    20701 ttaaaatata ctttcataag tattcctgta atatattcta ctactgtcgg cactactaga
    20761 cataataaaa gcaatgcaaa tatattattg gggtcaataa atcttgagac ctctattata
    20821 atcgacattg caattgcata cattggttta aatggaccat ttaaaaatcc atcttcttga
    20881 aaatgccctt gtttataata actatataag ttttcaatta tccaacctat aaaaccatac
    20941 aagaaaaaat taaataaaaa atataataga gaacctacat tatccatgaa tattcctcct
    21001 agctgtttat acttattttt tctcatattc atggatttat tctaaatcaa agaaattata
    21061 tttaatttat ttaattaata ctttatatta tagattgtga cattctttag agttcaaact
    21121 ttttaggtat tctctaactt ccagtaaatt ttcaagtatc ttatgtgatt gtgatttaat
    21181 ttgctcatct ggctctttta aatctggtac atttatacat cttataccac cattgtatgc
    21241 agcttcaact cccataggcg aatcctctat gacaatacaa tttttgggat taacatttat
    21301 ctttttagct gcttttaaga atatctcagg gtttggttta gagtttacaa catcatctcc
    21361 acaaactata gcatcaaagt aatcttttaa atttgcctta gctaatctct ttactgctct
    21421 ttctctcttt gttgatgttg caacagccat tttgtatcca ttttccttta aaaaagagat
    21481 tagttcattg actcctaatt tgataggagc tcccttcctc tccataaatt caatcatatt
    21541 tttagttttt tcgtcatata aatctattat tggtacagaa ctatcgtata tatctgtaag
    21601 accttctatt attcctttac gatttcttcc cataactgat gtataaattt ccttagtcat
    21661 agtatatcca tacttttcaa acgtctccat ccaaaattca agagaaattc tctctgagtc
    21721 aaacaaaact ccatccatgt caaaaataat tccttctaca ttttgcatac aattcctcca
    21781 atattttttg atataattat attacacttt ttatgattaa ttttacaacc ctcaatttat
    21841 ccaattctaa tattgtaaaa ttgtaatttt caaaagttac actttggttt actttaatat
    21901 ttgaaccaag catataggat atccatccac ctatactgtc aaatccatca tgctctatat
    21961 caagtccaaa atacttatta atatagttga tagattcagt tccatcaact aagtaagaac
    22021 ctgctcctat tttcttaata tgagtctctt ctttgtcaaa ttcatcttga atttctccaa
    22081 ctatctcttc tagtatatct tctattgtta ccacaccaga tgtaccacca tattcatcca
    22141 caactatagc aagttgaagt ttttcctttc ttattctctc aagagcttta tctatagtta
    22201 aattttcaga tatatatata atatctctca atatttcttc tagttcaatt ttattttcat
    22261 ttatcttttg attgtataaa tctcttatat gtacaaaacc taatatatca tctttatttt
    22321 ttctgcatac tggatatctt gtaacacctt cctcttttaa aatagctaat atcttttctt
    22381 cagaatcact ttcatatata cataccatat cagttctagg aaccattatc tctctaattt
    22441 tcttttcttc aaattcaaaa atattatcaa ctaatctttg ctctgattca tctataagtc
    22501 cacttttata actttcttct actaatagtc ttatttcgtc acctgtatgg ggttcatcaa
    22561 cctcatcagc ttgtgaatat ccaaatggtt taagaaataa atcagtactt aagttgaaaa
    22621 aatatattat tggatatgtt aacttataaa atcctactaa taaaaaagat gtactcaaca
    22681 ttattttttc tgtattataa agtgctaaag ctttaggaac caactctcct attacaacct
    22741 ccatcattgt tataattaaa aaagaaatgg aaattgatat agtatatata atactttcac
    22801 taagattaaa tacacttact attggtaaaa ttaactcttt aactgtagat tctcccatcc
    22861 aacctaatgc aagtgaacaa agtgttatac caagttgaca tgcagaaaga taggaattta
    22921 agttgtcttt tattatttta catctttttg cattattatt accttcagtt atcatggtat
    22981 caatcctaga actacgaagt tttaccatag caaattcaca agctacaaaa aaagcattta
    23041 tcaaaacaag cattactata agtgttactt ttaataactc ccgcataaag tattggttct
    23101 tataatgtaa gaaatctata agaactcaaa gttcccccct tatattaata aatttaattt
    23161 ataatatata ttctatcata tttattaata tatcctactt tattacaaat aatttttata
    23221 aactaaataa ccccttttaa tatttatgac tggctatttg ataaatatta aaggggttat
    23281 ttagttatca ttttttattt ctaaaaatct tttctcaaat gatttagtta tctatttatc
    23341 caatttttta cataatttaa tgattaaaaa tattaatttt ttc
//
LOCUS       DAMKNB010000057        23311 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.059, whole genome shotgun sequence.
ACCESSION   DAMKNB010000057 DAMKNB010000000
VERSION     DAMKNB010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 23311)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23311)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23311
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.059"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            163..1347
                     /locus_tag="PC494_002470"
     CDS             163..1347
                     /locus_tag="PC494_002470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3912962.1"
                     /translation="MQKSVKKAKVTGSMLAIFGVASVLFSSHAGGGFATGNQETQYYV
                     QYGWTAPLMAILAMIILTATMREVIIMYNNNNCRNYKDLFCELWRPYPKLEIIWEIYY
                     YLMVLIAVSAVIAGAAAVFQSIGVNYFVAVFIIGVVLLVFTIFGAMLVSKAATAMTIA
                     ILVCTLTIFIVGIKAKVPEITEILSNRTSFTPGYIKPILNTFIYAGFQSVVIPTLAGC
                     SRPLLKNSKEATKAMIISFVMNAIALGLAVTMLMGWYREIIAAGQTTLPTLYVAGQSG
                     NHTIYIIYNVALFLCLMSTGVTTIFGLVNRFEDHKALSFLSSRMKRRVFTACAIMVVS
                     MLISLTGLSNIVKYGYGYCGYLGLFTIVIPFLTLGHYKNKKFAKENPEAKWPAELNEN
                     VN"
     gene            complement(1724..2833)
                     /locus_tag="PC494_002471"
     CDS             complement(1724..2833)
                     /locus_tag="PC494_002471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HDF3912963.1"
                     /translation="MDFKSLGISENTINILKKLGITTPTPIQKESIKLIKEGKDVIAE
                     AQTGTGKTLAFLLPIFENISLDINDIQVLILSPTRELAIQITEEAMKLKESKDVSILA
                     AYGGKDIGSQIKKLKGNIHMIIATPGRLLDHLNRKTIDLSKLKTFVLDEADQMLLMGF
                     KNEVEAILKETSNKKQTLCFSATINSQVKKLAYRYTKNPVVVSIQKEEITLNNIKQEV
                     VETTDRKKLDALCKVLDEDNPFMAIIFCRTKRRVDHLEEALAIRGYNCQKLHSDIAQS
                     KRERIMKSFRSLDIQYLIATDVASRGLDISGVSHIYNYDLPETPEDYIHRIGRTGRAG
                     EEGYTCAFIDPKNERMLSEIETAIESKISRRIIEL"
     gene            3296..4489
                     /gene="nifV"
                     /locus_tag="PC494_002472"
     CDS             3296..4489
                     /gene="nifV"
                     /locus_tag="PC494_002472"
                     /EC_number="2.3.3.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homocitrate synthase"
                     /protein_id="HDF3912964.1"
                     /translation="MCVISKDRAKEIKIVDTTLRDGEQTAGVVFANREKIMIAEMLSD
                     LGVDQIEVGIPTMGGDEKNVIKHICSRNLKSDIMAWNRAVIKDVEESISCGVDAVAIS
                     ISVSDIHIENKLRTSRGWVLENMAKTVEFAKKNGLYVSVNGEDASRADIDFLTEFINV
                     GKQAGADRFRYCDTVGVMNPFSIKNAIETLYERTNFDIEMHTHNDFGMATANALAGIA
                     AGANYVGVTVNGLGERAGNAALEEVLMALKCVYKCDLNNIDTRKFRGICEYVAQASGR
                     ILPTWKPVVGDNMFIHESGIHADGALKDPHNYEPFDPSEVNLERKIVIGKHSGRAAVV
                     NKLSEYEMYISPENATKLLNAIRATSIRLKRSLMDKEILQLYCDILAHEKGTTEEEAV
                     RGSYI"
     gene            4514..6439
                     /locus_tag="PC494_002473"
     CDS             4514..6439
                     /locus_tag="PC494_002473"
                     /EC_number="4.2.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aconitate hydratase"
                     /protein_id="HDF3912965.1"
                     /translation="MGDNIVYKIIKKHIVDGEAVAGSSIGIKIDQTLTQDSTGTMTYL
                     QLEAMGIDKVKTKRSVAFVDHNMLQQGFENADDHKYIQTVADKYGVYFSKPGNGICHQ
                     VFLERFSTPGDTLLGSDSHTPTAGGVGMMAIGAGGLDVALAMAGGAYYIKAPKVCKVN
                     LVGKLNNMVSSKDIILEVLRKQTVKGGVGKVYEYGGEGVKSLSVPQRATITNMGAELG
                     ATTSIFPSDEKTLEFFKSQGREDAWVELKPDADAVYDEEITINLDELKPLAAKPHSPD
                     NVDEVENIGKIKIDQVAIGSCTNSSYEDLMKVAQILKGNKVHKDVSLVIAPGSRQVME
                     MIARNGALADIISAGARILENSCGPCIGMGQSPGTDSVSLRTFNRNFYGRSGTLSAQV
                     YLVSPEVAAVSAIKGVLTDPREFDIKFTNLDVNEFLIDDSMIIKPADVGSDVEVVRGP
                     NIKPFPLNTELSQSIGGKVILKTEDNITTDHIMPSNAKLLPFRSNIPYLANYCFNTVD
                     TEFPQRAKDNNGGFIVGGDNYGQGSSREHAALAPLYLGVKGVIVKSFARIHKANLINS
                     GIIPMEFCDEKDYENISLLDNLEIPNILDNLGSGILEVKNTTKGTSFKVKVELSAKEV
                     DVLKAGGKLNYTKNQAN"
     gene            6461..7456
                     /locus_tag="PC494_002474"
     CDS             6461..7456
                     /locus_tag="PC494_002474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isocitrate/isopropylmalate dehydrogenase family
                     protein"
                     /protein_id="HDF3912966.1"
                     /translation="MYKVTLIPGDGIGPEVAKAMKKVVEATGVEIEWEEVNAGEAVIE
                     EYGTPLPEYIIDSIKKNKIAIKGPITTPVGKGFRSVNVTLRQALDLYVNLRPIKSFKG
                     IKSRYEDVDLVVVRENTEDLYAGIEHKIGDYAAESIKIITRSASERIVDFACNYVKDN
                     KRKKVTAIHKANIMKMSDGLFLDVFREVASKHGVEYDDLIVDAAAMNLVLNPENYDVM
                     VMPNLYGDILSDLGAGLVGGLGIIPSANIGKDCAIFEAVHGSAPQIAGQNKANPTALI
                     QSSVMMLRYLGEYENAQKIETALEKVFLEGSKLTVDLGGSASTTEFADEVCKYIV"
     gene            7782..8255
                     /locus_tag="PC494_002475"
     CDS             7782..8255
                     /locus_tag="PC494_002475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HDF3912967.1"
                     /translation="MVVSVEVCLIKTLDSNILREVGTLSRAVNSINDIKYKELKLQKG
                     QFTFLTRICENPGINLVELSNMLKVDKATTTKAIQKLIKAGYVDKKQDEFDKRGYNLT
                     PTDKSLEVYELIIEEENRSIEICFDNFTDEEKQVVTKLLEKMSKNVENEWFKVKR"
     gene            8289..8783
                     /locus_tag="PC494_002476"
     CDS             8289..8783
                     /locus_tag="PC494_002476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDF3912968.1"
                     /translation="MIRKANMNDLESIMKIIKSTVEEMKTYNNTQWDENYPLEKDFVS
                     DIKKQDLYIYEVDGEVAGFICLNYEEPEEYLGLNWSSNKKAMVIHRMAVNPNFRKTGI
                     ASKLVDFAEKLAVENNVSYLKSDTYSINSKMNLLLTKCGFIKIGEMSFLGKEKSFYCY
                     DKIL"
     gene            8880..9401
                     /locus_tag="PC494_002477"
     CDS             8880..9401
                     /locus_tag="PC494_002477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase"
                     /protein_id="HDF3912969.1"
                     /translation="MIGFLKKRRSIRKYKDVEVEKEKLDKILKAALLAPSSKGLRTWE
                     FIVVDDKEKLINLSQCRTKGGGFFLKNAPLAIVIIADKEKNDVWIEDASIAASYIQLQ
                     AHELGLGSCWIQVRNRMHDDNIEADKYIREELKVPSKYSVECIISIGYPDEEKKAYSD
                     SDLDYKKVHFNNF"
     gene            9590..9901
                     /locus_tag="PC494_002478"
     CDS             9590..9901
                     /locus_tag="PC494_002478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HDF3912970.1"
                     /translation="MGIFKTKMDEDWKVNYIKEFNEMRDSYESKLQKKQFEVDSLKSE
                     LDRLRSYKNSLKPKEKQITDDDINNIKSLRRDGLSYKEISNQTSWSKATVSRVLNGLY
                     D"
     gene            9929..10615
                     /locus_tag="PC494_002479"
     CDS             9929..10615
                     /locus_tag="PC494_002479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HDF3912971.1"
                     /translation="MKYSYKKCIIDSILLMFIVQILRMILNYVLLSQFEFTLENFNII
                     NLISFTLVGLSLILFLKDNSLYNKVRNRKITEAFEENKNNILIEKCKLILFVVVLSLA
                     IIVTYCTKGYVLFNVTMMTLSVLIVPIFEELFFREYIWNYLSNFIKSKSKIICITSIL
                     SGIYNIGYIDVIRNYVILYNNSSYTFEVIISKIMIGTVFGIVLGLVKYRFRDVGFCIL
                     LRSLFAIFIR"
     gene            10847..11731
                     /locus_tag="PC494_002480"
     CDS             10847..11731
                     /locus_tag="PC494_002480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fumarylacetoacetate hydrolase family protein"
                     /protein_id="HDF3912972.1"
                     /translation="MKFVTFCSSNEEKIGVFNSETNSIYEINSLGLSKLYTDMNNFIE
                     NVSTGDLEKIKNNSFENAKCYKLEEVKLCSPIVRPKKDIICLGLNYKDHVNEIPDGVI
                     KNVVMPDYPIYFSKRADKIIGVDDKISLHGDLVEKLDYESELAVIIGKEGINISKEDA
                     YEYIFGYTIVNDISERALQDKHVQWFRGKSLDTHTSMGPYIVHKEEFEHPLKLDISSV
                     VNGEVRQNSNTEYFIFDIPTIINDLSRGMTLKPGDIISTGTPAGVAMGMNPQVYLKHG
                     DIVECKVEGIGVLKNIVD"
     gene            11830..13005
                     /locus_tag="PC494_002481"
     CDS             11830..13005
                     /locus_tag="PC494_002481"
                     /EC_number="2.1.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolecarboxamide
                     formyltransferase"
                     /protein_id="HDF3912973.1"
                     /translation="MARELELKYGCNPNQKPSKIYMKNGELPIEVLNGKPGYINFLDA
                     FNSWQLVKELKEATGLPAATSFKHVSPAGAAVGVPLSDTLKQIYFVDDLELSPLACAY
                     AMARGADRMSSYGDFIALSDVCDKETATIIAREVSDGIIAPGYTDEALEILKGKRKGN
                     YNIVKIDENYTPEPIETKDVYGITFEQGRNEILINEDLLKDIPTDNKIFTDSAKRDLI
                     IALITLKYTQSNSVCYAKDGQVIGVGAGQQSRIHCTRLAGNKADTWYLRQHPKVLNLK
                     FKKDIGRPDRDNTIDVYLSDDYMDVLADGIWQNFFEEKPEPLTGEGKRAWLKTLTGVA
                     LGSDAFFPFGDNIERAKRSGVSFIAQPGGSIRDDNVILTCNKYNIVMAFTKNRLFHH"
     gene            13133..13987
                     /locus_tag="PC494_002482"
     CDS             13133..13987
                     /locus_tag="PC494_002482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3912974.1"
                     /translation="MALNIRNYSLLCNQGTAKFNEDVVGINPFGAWVLDGATGLNGKN
                     LVSTESDARWYVQWWNRYLYKNINKEESLKSIINTGIIEVKKEYELRLNGFKVEKLDL
                     PSSSIVVVKFHENKVEYFLLGDCALFIKNGDSKVIKDRSICKFDNTVFDEMSKLSNLE
                     EMAFDEIRTSVMDTIVSNRLKKNTKEGYWILDFDEEAVENSIYGYIEIKKDFQLMLTS
                     DGFTSACDRYNLIKEEELIRIAEKFGIGYIHNKVRDFEDNDYKAVKVPRFKVKDDSSC
                     LYLDIYND"
     gene            14031..15266
                     /locus_tag="PC494_002483"
     CDS             14031..15266
                     /locus_tag="PC494_002483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HDF3912975.1"
                     /translation="MKILHIITQKPNSTGSGIYLSGMIKGFEKIGHKQAVIAGIDVND
                     DVNCFPSEVSFYPVKYNCGELNFPVVGMSDSMPYESTRYKDLNIDMINRLKYQFKVNI
                     DKAMNDFKPELIICHHLYLLTAFVREMVKDIKVMSICHGTCLRQLNTIDLEKEYIIAN
                     IRKLDLIFALHENQKYDIIKTFGVSESKVVVIGSGYNDDIFYNKNYKIKDDKIKIVFA
                     GKICKSKGLIPFIKAISKLKYSKDLIEVNFAGTGSDIESYNEIVKLASKSPFKMNFLG
                     KLEQRDLAELFNRSQIFVLPSFYEGLPVVVLEALSCGTDVITTDILGVKEWIGSEINN
                     SGKIEYISLPFMEKEGIPKDEELYDFENNLYNAIDSKIQSLLNNSNKKTSVDMSKKTW
                     DGLAYRINEVILMDELCLV"
     gene            15367..16308
                     /locus_tag="PC494_002484"
     CDS             15367..16308
                     /locus_tag="PC494_002484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp25"
                     /protein_id="HDF3912976.1"
                     /translation="MRISKKVLALGISALLLSVSFPTSINALDKIENIQGVDKYETAG
                     LISDKQDFTTAVLINADSTMVDGIAASGLAGVNNAAILLTNKDDIPEATLQRLNRVTK
                     IYVIGGENSISKDVEKMLLMRRMQVIRIDGVDRVDTSYKIAGEIEKIKNSDKMFLVNG
                     FKDEADAVSVASVAYRDGAPIILTKDIPSAEEDTDLDPWFGVSPVPVYAIGGESTLSD
                     YIVSRYRATRIGGVDRYQTNKNVIEKFYNGAKEFYITSGDDLVYALVASPLAKNAPVV
                     LVSNKSDKSILSGASKVTAIGISDKSIIEQCLDAVKK"
     gene            complement(16359..16718)
                     /locus_tag="PC494_002485"
     CDS             complement(16359..16718)
                     /locus_tag="PC494_002485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3912977.1"
                     /translation="MDLFEVNIVLNSGTAGGMNPKLKIFNMVISTEVCHHDVTQDTLT
                     EFHSWLKTVFFEANCELIKISEMAVKKTNQEETVFWGRILAGEAFITNKGRKKINEKE
                     AYLHLIASSHIFYTIIK"
     gene            complement(16744..17208)
                     /locus_tag="PC494_002486"
     CDS             complement(16744..17208)
                     /locus_tag="PC494_002486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF3912978.1"
                     /translation="MNLGNSLFQARKKHGLSQEDVAEKLGVSRQTVSKWETDETVPDI
                     RQSKKLAILYNVSLDELIDFDIDMEEIQEAINKTSEETEEKINWTNAWGKKYPILLKY
                     QTDVNISNYAYKVNMMLDELKQEYQYNELEAMLILKDILYNVWKNRKSKRKQ"
     gene            complement(17376..17584)
                     /locus_tag="PC494_002487"
                     /pseudo
     CDS             complement(17376..17584)
                     /locus_tag="PC494_002487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004071281.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3788 family protein"
     gene            complement(17628..17981)
                     /locus_tag="PC494_002488"
     CDS             complement(17628..17981)
                     /locus_tag="PC494_002488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HDF3912979.1"
                     /translation="MDRKRELKQLYKEMKFDTGVFIIKNDITKKIYLGKSNDIKSKFN
                     SLKFQLGAGSCMIKELNNEWKKYGEKAFTFEVLELIKHDDNKTEKDYLEELDILEMVW
                     LEKLKEDNTYEIYSI"
     gene            18277..19188
                     /locus_tag="PC494_002489"
     CDS             18277..19188
                     /locus_tag="PC494_002489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CGNR zinc finger domain-containing protein"
                     /protein_id="HDF3912980.1"
                     /translation="MNKKIELIGNFASDWIRYSDYEYKITEEDELYIVPTEDAVFTMY
                     NPFDVADDIIVDIIRIGQEALQDISKETKEMKLKKEILEFVKKYGLLGLIYSSVYNRD
                     IVGEERVLMIEKNYITKENILSTDEYVNMFIPFASDEDVYFKKYRRGIDVSKREESPK
                     FFGKRPLILDLVFSKFYTEQLDWIVSFAKDMCKHFNQICVYKNTSNLLTESVTIMSGG
                     FNPQKIGFSISQLDKPIIAWEFDSLKTAIETIYAFAITSEPSSLNKCKYCGKIYIPTN
                     SKSQYCSPSCRNCSNVKKSRSRAKKDK"
     gene            19449..19883
                     /locus_tag="PC494_002490"
     CDS             19449..19883
                     /locus_tag="PC494_002490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3912981.1"
                     /translation="MISPIILSSINQNLKEIERNELLETNIESGDYGLALSESDVKDI
                     INSRDNTLKGYGRIELDIKVTKQLIENIYTSQYTNVDNYLEAINDMQEIFYYLKNETD
                     DKICDDEIIEILGDFYEKFSGNMDNVRGEADEFAKKFKFGEV"
     gene            19906..21441
                     /locus_tag="PC494_002491"
     CDS             19906..21441
                     /locus_tag="PC494_002491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3912982.1"
                     /translation="MLNNLSNININENNLIKNQYSISLLKECLNCKVIDEREVYNIQQ
                     EISLILMDLIKKYTNGQSTSVKTEVAEKLLISIWYAIDAYINKLGDIEKRVVELTAKN
                     VKKVYLGGIEILEEELVRLKDFYKLMMSRKLDTNSIAYNDTLMELSSFFKSYIVKFEA
                     QDVPVSIDYPLALDDMDVKGIYYVKNYIESIDIENRFCNLFKKKDREKLFYDYGVTYK
                     IDCDVILVNLFELIMNNCIFSTILGNEVTNLEISKYEYEFLEKQFKNMYNNITEDKVI
                     DSEESNIIELIEVDDSFNTEVDSNLDYNDFEEINREIRINKKITLLLMEAIEVLIKRL
                     SIEDEDVIRYIKKYEKIFIESVLSSIKSNTFKSMVTVSKNKNEHLEDYIVDDESKLDD
                     ESFREIFNEILDSTSIIEKIRIIKENINAKKDFIDILESECLFGEEYLMLFASLSELE
                     LAILGSVVFYEDIRMREINILEFMLNEKTETTLWKIEYIKFMKRQSEDKIYSIEEHMN
                     KIN"
     gene            21525..22892
                     /locus_tag="PC494_002492"
     CDS             21525..22892
                     /locus_tag="PC494_002492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HDF3912983.1"
                     /translation="MKEYIINNVEEIREELIDLSKKIWENPELAFEEKYASSIQKEYL
                     KSKGFKIEEVENLPTGFIASFGEGKPVIGILGEYDALPELSQCVSAERKPLVEGKAGH
                     GCGHNLLGVAGVGAVVSIKKLIEENKFNGTIKYFGCPAEEEGGGKTVMCINGCFDDVD
                     CAFTWHPFDINAPWRGGSLANLSVKFKFKGITAHAAQAPHNGRSALDAVEIMNVGANY
                     LREHVIDSIRMHYVITNGGGRPNVVPGFAESWYFIRGKKAKDAEHVLDRLIKVAQGAA
                     MMTETEMEYKVTDGIYDYIPNQCLTDLVYDNMVFVGCPKNTPEEEEFAKKLCDTLTRE
                     ERLGVATSLQNDKSIVESYIHKEIVDGDKDKGLAGSTDVGDVSYVIPVAQFAMAAWPV
                     GIASHTWQSCSSAGSNIGFSAMINSAKVLACSAYDVFMDTKIIDEAKIEFDKSLDGQK
                     FKPLV"
     gene            22927..23151
                     /locus_tag="PC494_002493"
     CDS             22927..23151
                     /locus_tag="PC494_002493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NifU family protein"
                     /protein_id="HDF3912984.1"
                     /translation="MREKVEKVLEEKIKPVLQRDGGDVELIDVNENGVVLVRLQGACS
                     GCPGATMTIKAIIENVLVSEVPGVTQVLGV"
BASE COUNT         8989 a         2450 c         4186 g         7686 t
ORIGIN      
        1 aaaataaata tataaaaaat atttaatata aaggtagaaa taagttgaaa atgtaaagtc
       61 attggaaaaa tatagttgaa tttaatgagc aaaaatgtta ttgttttatc aataaagtgt
      121 taaaataaaa acttttaata tcattttagg gaggatgatt tcatgcaaaa aagtgtaaag
      181 aaagcaaaag taacgggctc tatgttagcc atttttggtg ttgcaagcgt tctttttagt
      241 tcacatgcag gaggaggatt tgctacaggg aatcaagaaa ctcagtacta tgtgcagtat
      301 ggatggacag caccacttat ggcaatttta gcaatgatta tacttactgc taccatgaga
      361 gaagttatca taatgtataa taataataat tgtaggaatt ataaggattt attttgtgag
      421 ctttggagac catatccaaa acttgaaata atatgggaga tatattacta tctaatggtt
      481 ttaatagctg taagtgctgt tatagcaggt gcagcagcag tatttcaaag tataggagta
      541 aattattttg tagctgtatt tattattgga gttgtacttc ttgtctttac tatatttggt
      601 gctatgcttg tatctaaagc agctacagca atgacaatag ctattctagt atgtactctt
      661 actattttta ttgttggtat aaaagctaaa gtaccagaaa taactgaaat attatcaaat
      721 agaacgagtt tcacacctgg ctatatcaag ccaatactta atacttttat ttatgcaggt
      781 tttcaatcgg ttgttatacc tacacttgca ggatgttcaa gaccacttct taagaactca
      841 aaagaagcta ctaaggcaat gataatttca tttgttatga atgcaattgc attaggactt
      901 gctgtaacta tgctaatggg atggtataga gaaattattg ctgctgggca aacaacactc
      961 cctactcttt atgttgcagg tcaatctgga aatcatacta tatacataat ttataatgtt
     1021 gcattattcc tttgtttaat gtctacagga gtaactacta tatttggtct tgtaaataga
     1081 tttgaagacc ataaagcact ttctttcctt tcttcaagaa tgaaaagaag ggtatttaca
     1141 gcttgtgcaa taatggtagt gtcaatgctt atatcactta caggattaag taatattgtt
     1201 aaatatggat atggatattg tggttatctt ggtctattca ctatagtaat tccattcctt
     1261 acactaggac attataagaa taagaagttt gcaaaggaaa atccagaagc taaatggcca
     1321 gcggaattaa atgaaaatgt aaattagatg tagtagcaaa aaatattgct aaagagaata
     1381 ctatagataa gaatactata gataatatat ctgcatgttt attaagatta tttgcaaaat
     1441 ctaatattaa acaactataa acaagcaata taaaactaag aataaaagat aaaaagaggg
     1501 tgtctcaaaa tggactttta gtttataagg cactcttttt tatatgaagt caagtatatt
     1561 ttcattattt tgacaataaa agagactaat cctactttgg atagcctctt ttttctttaa
     1621 tataaaatag tataacagca aagtatagat tgatacatgt tttctgtagc tttctatata
     1681 ttacagtgtt tgtgtggcat tggtatttta agcaatctat aaattataat tctataattc
     1741 ttctactaat tttagattct atagccgtct ctatttcact taacattcgt tcatttttag
     1801 ggtcaataaa agcacatgta tatccttctt caccagctct accagttctg ccaatacggt
     1861 ggatgtagtc ttctggtgtt tctggtaaat cgtaattata tatatgactt actccagata
     1921 tatcaagacc acgagaagct acatctgtag ctattaagta ttgtatatct aaacttctaa
     1981 atgatttcat tattctttct cgttttgatt gagcaatatc actatgaagt ttttgacaat
     2041 tatatcctct tatagcaaga gcttcttcaa gatggtcaac ccttctctta gttctacaaa
     2101 atattattgc cataaaagga ttatcttcat ctagtacctt acataaggca tctaattttt
     2161 ttctatctgt agtttctact acttcttgtt ttatattatt aagagtgatt tcttcttttt
     2221 gaatagaaac tacaacagga ttttttgtgt atctataagc taattttttt acttgagaat
     2281 ttatagttgc agaaaagcat agtgtttgct ttttgtttga agtctctttt aaaatagctt
     2341 ccacttcatt tttaaatccc ataagcaaca tttggtctgc ttcatctaaa acaaaagtct
     2401 tcaacttact aaggtctatt gtttttctat ttagatggtc taaaagccta cctggtgtag
     2461 ctataatcat atgaatattt ccttttagtt tctttatttg agaaccaata tcttttcctc
     2521 catatgctgc aagaatactt acatctttag attctttaag tttcatagct tcttctgtta
     2581 tttgaatagc tagttctctt gtaggagaaa gtataagtac ttgtatatca tttatatcta
     2641 atgatatatt ttcaaatatc ggaagtaaaa aagctagtgt ttttcctgtt ccagtttgag
     2701 cttctgctat tacatctttt ccttctttta ttagtttaat actttctttt tgtataggtg
     2761 taggtgttgt tattcctaat ttttttagaa tatttattgt attttcacta atccctaagc
     2821 ttttgaaatc cattgttatc ttacctttca tgaaaaattt tcttttttat taaccaatta
     2881 ataatatcat atttgtaagt atttttagta aattttttaa ttattattta tatagcttaa
     2941 aaatatatta agatacttta aaatggaatg taacttaaat taaattttag taggaatttt
     3001 ataggtttat ttttaaaggt tttttgaaaa taaatctatt taaaaattaa attaaaatgc
     3061 aagaaaaaca taataacttt catttttaag aagttttcac aaaaaagaaa aaatatagtg
     3121 caataaatga tacaaagtaa tataatagat tacaagatat gaaaagctaa aaaaataaat
     3181 tgcaaatgaa attaaaatga ataaaaaata aaaaaataat cataagttag aggtatcaat
     3241 gaaaaataag acttaatgtt tttaaaatta aaagtatact aaggggggca ttaatatgtg
     3301 cgttatatca aaagatagag caaaggaaat aaaaatagta gatactactt taagagatgg
     3361 agagcaaaca gctggggttg tatttgcaaa tagagaaaaa ataatgattg ctgaaatgtt
     3421 aagtgaccta ggtgttgacc aaattgaagt tggtatacct actatgggtg gagatgaaaa
     3481 aaatgtaata aagcacatat gtagtagaaa tttaaaatca gatataatgg cttggaatag
     3541 agcagtaata aaagatgttg aagaatctat ttcttgtggt gttgatgcag tagctatatc
     3601 aatatcagta tctgacattc atatagaaaa taaattgaga acttctagag gctgggtttt
     3661 agaaaatatg gctaaaacag ttgaatttgc aaagaaaaat ggattatatg tttcagtaaa
     3721 tggagaagat gcttcaagag cagatataga cttcttaact gaatttataa atgttggaaa
     3781 acaagcaggg gcagatagat ttagatactg tgatacagta ggagttatga atcctttttc
     3841 tataaagaat gcaatagaaa ctctttatga aagaactaat tttgatatag aaatgcatac
     3901 acataatgac tttgggatgg caactgcaaa tgcacttgca ggaatagcag caggagcaaa
     3961 ttatgttggt gttacagtaa atggattagg tgaaagagca ggaaatgcag cattagaaga
     4021 agttttaatg gcacttaagt gtgtttataa atgtgattta aataatatag atactagaaa
     4081 atttagagga atatgtgagt atgtagcaca ggcatcagga agaatacttc ctacatggaa
     4141 accagtagtt ggggataata tgtttataca tgaatctggt atacatgcag atggagcttt
     4201 aaaagaccca cataactatg aaccatttga cccaagtgaa gtaaatcttg aaagaaaaat
     4261 agtaataggt aaacattcgg gaagagctgc agttgtaaat aagttgagtg aatatgaaat
     4321 gtatatttct ccagaaaacg ctaccaagct attaaatgct ataagagcta catctataag
     4381 attaaaaaga agtttaatgg ataaagaaat tcttcaatta tattgtgata tactagcaca
     4441 tgagaaaggc acaacagaag aagaagcagt tagaggttca tatatttaag atataattgt
     4501 ttaggaggaa aatatgggag ataatatagt ttataaaata attaaaaaac atatagtaga
     4561 tggagaagct gttgctggaa gttcaattgg tataaaaata gaccaaactt taacacaaga
     4621 ttctactgga acaatgacat atcttcaact agaagctatg ggaatagata aagtaaagac
     4681 taaaagaagt gtggcatttg tagaccataa tatgttacaa caaggatttg aaaatgcaga
     4741 cgaccataag tatatacaaa cagtggcaga taaatatgga gtttatttct ctaagccagg
     4801 aaatggtatt tgtcatcaag tatttttaga aagattttca acaccaggag atacactttt
     4861 aggttctgat agccacacac ctactgctgg aggtgtgggc atgatggcta ttggagctgg
     4921 tggattagat gttgctttag ccatggcagg aggagcatac tatataaaag caccaaaagt
     4981 ctgtaaggtg aatctagttg gaaaattaaa taatatggta tcatcaaaag atataatatt
     5041 agaagtgtta agaaaacaaa ctgtaaaagg tggagtaggt aaagtttatg aatatggtgg
     5101 agaaggtgtc aaaagcctat ctgttccaca aagagctaca ataacaaata tgggggctga
     5161 acttggagca actacttcaa tcttcccaag tgatgaaaaa acactagaat tttttaagag
     5221 tcaaggaaga gaagacgcat gggtagagct aaaaccagat gcagatgcag tttatgatga
     5281 agagattact ataaacttgg atgaattaaa accattagct gcaaaacctc atagcccaga
     5341 caatgtagat gaagttgaaa atataggcaa gattaaaata gaccaagtgg caataggaag
     5401 ttgtacaaat tcttcttatg aagacttaat gaaagtagca caaatcctga aaggaaataa
     5461 agtacataag gatgtgagtt tggtaatagc accaggttca agacaagtta tggagatgat
     5521 tgctagaaat ggggctttgg cagatataat aagtgctgga gctagaatac tagaaaattc
     5581 ttgtggtcca tgtattggta tgggtcaatc tccaggtact gactctgtgt ctttaagaac
     5641 tttcaataga aatttctatg gtagaagtgg gactttgtca gcacaagtat atttagtaag
     5701 tccagaagtg gcagcagtaa gtgcaatcaa gggagtgctt acagacccaa gagaatttga
     5761 tattaaattt acaaatttag atgtaaatga atttttgata gatgatagca tgataattaa
     5821 acctgctgat gtaggaagtg atgtagaagt agttagagga cctaatataa aacctttccc
     5881 tcttaataca gagctaagtc agtctatagg tggaaaagtt atattaaaga cagaagataa
     5941 tataactact gaccatataa tgccatcaaa tgctaagtta cttcctttta gaagtaatat
     6001 accgtatctt gcaaactatt gtttcaatac tgtagataca gaatttcctc agagagcaaa
     6061 agacaataat ggtggattta tagttggtgg agataattat ggtcaaggtt caagtagaga
     6121 acatgcagct ttagcaccat tatatctagg tgttaaaggg gtaatagtta agagctttgc
     6181 aagaatccac aaggctaact tgataaatag tggtataatt ccaatggagt tttgtgatga
     6241 gaaagattat gaaaatatat ctcttttaga taatctggag ataccaaata ttttagacaa
     6301 tctaggtagt ggaattttag aagttaagaa tacaactaaa ggaacttctt ttaaggtcaa
     6361 agtagaattg tcagcaaaag aagttgatgt attaaaagct ggtggaaaat taaactacac
     6421 taaaaatcaa gctaattaat atgaaaagag ggaatattga atgtataaag tgacacttat
     6481 accaggagat ggaataggac cagaagttgc gaaagctatg aaaaaggtag tagaagctac
     6541 tggagtagaa atagaatggg aagaagttaa tgcaggagag gcagttattg aagagtatgg
     6601 tactccactt cctgaatata ttatagatag tataaaaaag aacaaaatag ctataaaagg
     6661 cccaattact actcctgtag gtaaaggatt taggagtgta aatgtaactt taagacaagc
     6721 attagatttg tatgtcaatt taagacctat taaaagtttt aaggggataa aatcaagata
     6781 tgaagatgtt gatttagtgg ttgtaagaga aaatacagaa gatttatatg ctggaataga
     6841 acataaaata ggtgattatg cagctgaaag tataaagata ataacaagaa gtgcaagtga
     6901 aagaatcgtt gattttgcat gtaactatgt taaagataat aagagaaaaa aagttacagc
     6961 tatacataag gcaaatataa tgaaaatgtc tgatggattg tttttagatg tgtttagaga
     7021 agttgcatca aaacatggtg tagaatatga tgatttgatt gtagatgcag cagctatgaa
     7081 cttagtttta aatccagaaa attatgatgt aatggtaatg ccaaatcttt atggagatat
     7141 actatcagat ttaggtgctg ggcttgttgg aggtttaggt ataattccaa gtgcaaatat
     7201 tggtaaagat tgtgcgatat ttgaagctgt tcatggaagt gctccacaaa tagcaggtca
     7261 aaataaggct aatccaacag cacttattca atcatcagta atgatgctta gatacttagg
     7321 tgaatatgaa aatgcacaaa aaatagaaac agctttagaa aaagtatttc ttgaaggaag
     7381 taaattgact gtagatttag gtggctcagc ttctactaca gagtttgcgg atgaggtgtg
     7441 taagtatatt gtatagattt tatttaggga aaaagtaaaa tatagattga agaaaagagg
     7501 ctttctcaaa atagagataa gcctttttta ttggaatgat aaaatatatt tgattttata
     7561 caaaagagag ttcctcataa acgaaaaagt taattttggg atatccattt taattttaaa
     7621 attaattgat taatatgcaa agaaagatta aataaattta ttatttttaa ttgaactttc
     7681 aaccaaaata tggtaaaatt taaaaaagtt gaactttcaa ctaaaaatga atatattgat
     7741 tatgtgaaat tctataaaac agaaactatt tgactttagc catagtagtt tcagtggagg
     7801 tgtgtttgat taagacttta gacagtaata tattaagaga agtaggtact ttatctagag
     7861 cagtaaattc aataaatgat attaagtaca aggaattaaa gttacaaaaa ggacaattta
     7921 catttttgac aagaatctgt gaaaatcctg gtataaatct tgtggaatta tcaaatatgt
     7981 taaaggtaga caaggctaca acaaccaagg ctatacaaaa attaataaag gcaggatatg
     8041 tagataaaaa gcaggatgag tttgataaaa gaggatataa tttaactcca actgataaat
     8101 ctttggaagt ttatgagttg ataattgaag aagagaatag aagtatagag atatgttttg
     8161 ataattttac agatgaagaa aaacaagtgg taactaagtt attagaaaaa atgagcaaaa
     8221 acgtagaaaa tgaatggttt aaagtaaaga gatagtaaat aaatacatta acttaaggag
     8281 atatttttat gattagaaaa gcgaatatga atgatttaga aagcattatg aaaattataa
     8341 aatctacagt ggaagaaatg aagacttata ataatacaca atgggatgaa aactatccat
     8401 tagaaaaaga ctttgtttca gatattaaga aacaagattt atatatttat gaagtggatg
     8461 gagaagtagc agggtttata tgtcttaatt atgaagagcc agaagaatat ttaggcttaa
     8521 attggtcatc taataaaaaa gcaatggtaa tacatagaat ggctgtaaat ccaaacttta
     8581 gaaagacagg gatagcatct aagttagttg attttgctga aaaattagct gtagaaaaca
     8641 atgtatcata cttaaagagc gatacatatt caataaactc aaaaatgaat ttattactta
     8701 caaagtgtgg ttttataaaa atcggagaaa tgagtttttt aggaaaggag aaatctttct
     8761 actgttatga taaaatatta taaagagcat ttacaataca aggggtaaat aatagatttt
     8821 cagcattagt aagggcataa tataacttag tatatgctat tatgaaaggg atgatttata
     8881 tgattggatt tctaaagaaa agaagaagta ttagaaaata caaggatgtt gaagtagaaa
     8941 aagaaaaatt agataaaata ttaaaagctg ctcttttagc tccatcatca aaggggctta
     9001 gaacatggga atttatagtg gtagatgata aagaaaagct aattaattta tctcaatgta
     9061 gaactaaagg tggtggattt ttcttaaaaa atgcaccttt agctattgta attattgcag
     9121 ataaagaaaa aaatgatgtt tggatagagg atgcaagtat agctgcttca tacatacaac
     9181 ttcaagctca tgaactaggt ttaggttctt gttggataca agtaagaaat agaatgcatg
     9241 atgataatat agaagctgat aagtacatta gagaagaatt aaaagtacct agcaagtaca
     9301 gtgtagaatg tataatttct ataggatatc ctgatgaaga aaagaaagca tacagtgact
     9361 ctgatttaga ctataaaaag gttcatttta acaactttta gtatataata tgttgtatta
     9421 agacattata tttttttcta ttgttaatat atacttaaaa ttgtaaaaat atatctgaat
     9481 tttactaact tatctagggg ttatgtacaa ggattttaaa gataaatata gaaattaatg
     9541 tttataatcg atacataact tgagtaacaa aatttaagga ggttaaagta tgggtatatt
     9601 taaaacaaaa atggatgagg actggaaagt aaactacatt aaagagttta atgaaatgag
     9661 agattcttat gagagtaaac ttcaaaaaaa acagtttgag gtagatagtt tgaaatcaga
     9721 attggataga ctaagaagct ataaaaatag ccttaagcca aaagaaaaac aaattactga
     9781 tgatgatata aataatataa agagtttaag aagagatggc ttaagctata aagaaatttc
     9841 aaatcaaaca agttggagca aagcaactgt aagtagggta ttaaatggac tttacgatta
     9901 gcatatacat ggggtgattt aaattgggat gaagtatagt tacaaaaaat gcataataga
     9961 ttctatttta ttgatgttta tagttcaaat attaaggatg attttgaatt atgtacttct
    10021 aagtcaattt gaatttactc ttgaaaattt taatattata aacttaattt cttttacatt
    10081 agttggttta tcgttaattt tatttttaaa agataattct ttgtataaca aggttagaaa
    10141 tagaaaaatc acagaagctt ttgaagaaaa taaaaacaat atacttattg aaaagtgtaa
    10201 gctgatactt tttgttgtgg ttttatcttt agcaataatt gtaacttatt gtactaaggg
    10261 atatgtactt tttaatgtaa ctatgatgac tttgtctgta ttgatagttc caatatttga
    10321 agagttattt tttagagaat atatatggaa ctatctaagt aattttataa agtcaaagag
    10381 taaaattatc tgtataacat ctatactatc tggaatttat aatataggat acatagatgt
    10441 tataagaaat tatgtaatat tgtataacaa ttcgagctac acctttgaag ttattatttc
    10501 aaaaattatg ataggtactg tttttggtat tgtacttgga ttagttaagt ataggtttag
    10561 agatgtaggg ttttgtatat tattgaggag cttatttgct atatttatta ggtagatagt
    10621 ataatcggtt tataaggttg ttttaaattt aattttaaat caaccttatt ttatttgtgt
    10681 tttataaagc acttatatat taataactaa taaatttaat aaaaattatt tgaatatttt
    10741 taaaatatat aaatatgtat tgacatataa atattatgaa ttacaattta tataaactaa
    10801 taaaaattaa ataatattaa tcaacttatt gaatggagga ataaaaatga aatttgtgac
    10861 tttttgtagt agcaatgaag aaaaaatagg tgtatttaat tcagaaacaa atagtatata
    10921 tgaaattaat agtttaggat taagtaaatt atatactgat atgaataatt ttattgaaaa
    10981 cgtatctaca ggagatttag aaaaaataaa aaacaattca tttgaaaacg caaagtgtta
    11041 taagttagaa gaagttaaat tatgttcccc aattgtaaga cctaaaaaag atattatatg
    11101 tttaggtcta aactataaag accatgtcaa tgaaatccca gatggagtta taaaaaacgt
    11161 agttatgcca gattatccaa tttatttttc taagagagca gacaaaataa ttggagtgga
    11221 tgataagata agcttacatg gagatttggt agagaagttg gactatgaat cagaacttgc
    11281 agtaatcata ggtaaagaag gtataaatat atcaaaagaa gatgcttatg aatatatatt
    11341 tggatataca atagtaaatg atataagtga aagagcactt caagataaac atgttcaatg
    11401 gtttagagga aaaagcttag acacacatac atctatggga ccttatatag tacataaaga
    11461 agaatttgaa catcctttaa aattagatat aagtagtgta gtaaatggag aagtaagaca
    11521 aaattctaat acagagtact ttatatttga tatacctact ataataaatg atttatcaag
    11581 aggaatgact ctaaagccag gagatataat ttcaactgga actccagcag gggttgctat
    11641 ggggatgaat cctcaagtat atttaaagca tggcgatata gttgaatgta aagtcgaagg
    11701 aataggagtt ttaaaaaata tagttgatta atggataaat atgccatata attttattag
    11761 tacgaataat ttaattaata taggattaat caaacttatg attaatttat tatagagagg
    11821 gatgagtata tggcaagaga actagaatta aagtatggct gtaatccaaa tcaaaaacca
    11881 tcaaagattt atatgaagaa tggagaactt cctatagaag tattaaatgg aaaacctgga
    11941 tatataaatt ttttagatgc atttaatagt tggcaacttg tgaaggaatt aaaagaagct
    12001 acaggtctcc cagcagcaac ttcatttaaa catgtaagtc cagcaggagc agcagtaggg
    12061 gtacctttat cagatacttt aaagcaaata tattttgttg atgatttaga gctttctcca
    12121 ttagcttgtg cttatgcaat ggcaagagga gcagatagaa tgtcttctta tggcgatttt
    12181 atagcacttt cagatgtatg tgataaggag actgcaacta ttatagcaag agaggtttct
    12241 gatggtataa tagctccagg atatacagat gaagcccttg aaatattaaa aggaaagcgt
    12301 aaaggcaact ataatattgt aaaaatagat gaaaattata ctcctgaacc tattgaaaca
    12361 aaggatgttt atggaattac ttttgaacaa ggtagaaatg aaatattaat aaatgaagac
    12421 ctattaaaag atattccaac tgataataaa atttttacag atagtgcaaa acgtgattta
    12481 attatagctc ttattacatt aaaatataca caatcaaatt ctgtttgtta tgctaaagat
    12541 ggacaagtaa taggggtagg tgcaggtcaa caatcacgta ttcattgtac tagacttgca
    12601 ggtaacaaag ctgatacttg gtatcttcgt caacatccta aagtattaaa cttaaaattt
    12661 aaaaaggata taggtcgtcc agatagagat aacactattg atgtatatct ttctgatgat
    12721 tatatggatg tgcttgctga tggcatatgg caaaactttt ttgaagaaaa accagagcct
    12781 ctaactggag aaggaaaaag agcatggctt aaaactttaa caggagtagc acttggttca
    12841 gatgcatttt tcccatttgg agataatata gaacgtgcaa aaagaagtgg ggtaagtttt
    12901 atagcacaac caggtggttc tattcgtgat gataatgtta tattaacttg taataagtat
    12961 aacatagtca tggcatttac taaaaataga ttattccatc attaaaatac tgaaagtata
    13021 aagataatat agattaggta aaaatctaca acaagttttg ttgtagattt ttttatttgc
    13081 tgtataattt taaatagaac tttattttta gatattcaat ttggaggttg atatggcttt
    13141 aaatataaga aactatagcc tattatgtaa tcaaggaaca gctaaattta atgaagatgt
    13201 agtcggtata aatccatttg gggcatgggt tttagatggt gctacaggac ttaatggaaa
    13261 aaatttagtg tcaactgaaa gtgacgcaag gtggtatgtt cagtggtgga ataggtattt
    13321 atataaaaat ataaataaag aagaatcatt aaagagtatt attaatactg gaataataga
    13381 agtaaaaaaa gagtatgaac taagattaaa tgggtttaag gttgaaaaat tagatttacc
    13441 atctagttct atagttgttg taaaatttca tgaaaataaa gtagagtatt ttttattagg
    13501 agattgtgct ttgtttatta aaaatggaga ttccaaagtt ataaaagata ggagtatttg
    13561 taaatttgat aatactgtat ttgatgaaat gagtaaactt tctaacttgg aagagatggc
    13621 ttttgatgag attagaacta gtgttatgga tacaatagta agcaatagat tgaagaaaaa
    13681 tacaaaagag ggctattgga tattggattt tgatgaggaa gctgtggaaa attctatata
    13741 tggatacatt gaaataaaaa aagattttca attgatgcta acgagtgatg gttttacaag
    13801 tgcatgtgat agatataatc taataaaaga agaagaattg atacgtatag cagaaaaatt
    13861 tggtatagga tatatacata ataaagtaag ggattttgaa gataatgact ataaagcggt
    13921 taaagtgcca agatttaaag taaaagatga ttcatcttgt ttatatttag atatatataa
    13981 tgattagact gtataaaact atttaatttt agaaaggagg caagtgaaaa gtgaaaattc
    14041 ttcatataat aacacaaaaa ccaaatagta caggtagtgg tatatatttg tctggtatga
    14101 taaaagggtt cgaaaaaatc ggtcataagc aagctgtaat tgcaggtata gatgtaaatg
    14161 atgatgtaaa ttgttttcca agtgaagtaa gtttttatcc agtaaagtat aattgtgggg
    14221 agttaaattt tcctgttgta ggtatgagtg attctatgcc atatgaaagt acaagatata
    14281 aagatttaaa tatagacatg ataaatagat tgaaatatca atttaaagta aatatagata
    14341 aggctatgaa tgattttaaa ccagaactta taatatgtca tcatttgtac ctcttaactg
    14401 catttgttag ggaaatggta aaagatataa aggttatgtc tatttgtcat ggaacttgtt
    14461 taagacagtt aaataccatt gatttagaga aagaatacat aatagcaaat ataaggaaat
    14521 tagatttaat atttgctctt catgaaaatc agaaatatga tattataaag acttttggag
    14581 taagtgaaag taaagtagtt gtaattggta gtggttataa tgatgatata ttttataata
    14641 aaaattataa aataaaggat gataaaataa aaatagtatt tgcaggtaag atatgtaaat
    14701 caaagggact gattccattt ataaaagcta tatctaaatt aaaatatagt aaagatttaa
    14761 tagaagtcaa ttttgcaggt actggaagcg atatcgaatc atataatgag atagttaaac
    14821 tggcaagtaa gtctccattt aaaatgaatt tcctaggaaa gttagaacag agagatttag
    14881 ctgagctatt caacaggtca caaatatttg tgttaccatc attttatgag ggattaccag
    14941 ttgtagtttt agaagcttta tcttgtggca cagatgtaat cactactgat attcttggtg
    15001 ttaaagagtg gattggtagt gagattaata attctggaaa gatagaatat atttctctac
    15061 cttttatgga gaaagaaggt attccaaaag atgaagagtt atatgatttt gaaaataatt
    15121 tgtataatgc aatagattct aagatacaat ctttattgaa taactcaaat aagaaaacat
    15181 ctgtagatat gtcaaaaaaa acgtgggatg gcttagcata tagaataaat gaagttattt
    15241 taatggatga attgtgttta gtctaaaatt atttaaatta taaaaaagtg taactatttt
    15301 tacactattt ttaaatgatt ttatattata ctaatactaa atatatttgt tttagggagg
    15361 taatttatga ggattagtaa aaaggtattg gcgttaggta tttcagcatt actgttaagt
    15421 gttagttttc caacatcaat aaacgcacta gataagattg aaaatattca aggagtagat
    15481 aaatatgaaa cagctgggct tatttcagat aagcaagatt ttacaacagc agttcttatc
    15541 aatgcagatt ctacaatggt agatggaatt gctgcaagtg gtcttgcagg agtaaataat
    15601 gcagctattt tattaactaa taaggatgat ataccagaag caacgcttca aagactgaat
    15661 agagttacta agatatatgt aataggtgga gaaaattcta taagtaaaga tgtagaaaaa
    15721 atgttactta tgagaagaat gcaagttata agaattgatg gtgtagatag agtagataca
    15781 agttataaaa ttgcaggcga aatagaaaaa attaaaaaca gtgataagat gtttttagta
    15841 aatggattta aggatgaagc tgatgcagta agtgttgcat ctgttgctta tagagatgga
    15901 gctcctataa tattgacaaa agatatacct tcagcagaag aagacacaga cttagaccca
    15961 tggtttggag tttctcctgt tccagtatat gctattggag gagagtctac attaagtgat
    16021 tacatagtga gcagatatag agcaactaga attggcggtg ttgatagata tcaaactaat
    16081 aaaaatgtta ttgaaaagtt ctataatgga gcaaaagagt tctatataac aagtggagac
    16141 gatttagttt atgctttagt tgcatcacca cttgcaaaaa atgctcctgt tgttttagtt
    16201 tcaaataaaa gtgataagag tatattaagt ggagctagta aagtaacagc aataggtata
    16261 agtgataaga gtattataga gcaatgtttg gatgctgtaa agaagtaatg gagtgttatt
    16321 agtaaaatga atatacacat tgaaaattag tagattgttc attttataat ggtataaaat
    16381 atatgggaag aggctatcaa atggagataa gcctcttttt catttatttt tttgcgtccc
    16441 ttattggtaa taaaagcttc ccctgctaaa attcttcccc aaaatacggt ttcttcttgg
    16501 ttggtttttt ttacagccat ttcagatatt tttatcaatt cacagtttgc ttcaaaaaat
    16561 acggttttca accatgagtg aaattctgtc agagtatctt gtgtaacatc atgatgacaa
    16621 acttccgtag atattaccat attaaatatt ttcaattttg ggttcattcc acctgctgtc
    16681 cctgaattga gaacgatatt tacttcaaaa aggtcaatac tttagtttcc aaaaaacggg
    16741 gatttattgc tttcgtttac tttttcgatt tttccagaca ttgtataaaa tatctttaag
    16801 aattaacatt gcttccagtt cattatattg gtattcctgt tttaattcgt ccaacatcat
    16861 gttaacctta taagcataat tagaaatatt aacatctgtc tgatatttaa gaagaatagg
    16921 gtattttttt ccccaggcat ttgtccaatt gattttttct tcggtttcct cacttgtttt
    16981 attaatcgct tcctgaattt cttccatgtc aatatcaaaa tcaatcaatt catctaatga
    17041 cacattgtaa agtattgcta atttttttga ctgacgaatg tctgggactg tttcatccgt
    17101 ttcccatttt gaaacagtct gcctgcttac ccccagtttt tcagctacat cttcctgtga
    17161 aagcccatgt ttcttccttg cctgaaataa actatttcct aaattcattg aaattcctcc
    17221 ttatctgttt atgggattat tatattattt gataagaaca aactctacca actaaaatta
    17281 tcatatttgc tatttttatt aacataattc aaagacgtat ttattctgca aattaaaatc
    17341 tgctaacctc tgcgaatatc aatcattaac cacttttatc cattccctgt ttttgtttgt
    17401 acgtaaatat ctcttaattc tggtgtaaac tcctgtaaaa tcgcttcgac aacctctttc
    17461 tctttctttc aaacaacaac taaaacgtaa aataattttc tttcggatat actgtgcata
    17521 aattttttct aggtttttta aatttgatat tccagccaaa ttcccaactg caagaactaa
    17581 atatctattt tgagacacta tctccttttc ttatattata ttatttttta tatggaataa
    17641 atttcataag tattatcttc ctttaatttt tctaaccaaa ccatttctaa aatatctagt
    17701 tcttctaaat agtctttctc tgttttgtta tcatcatgtt ttataagctc taaaacttca
    17761 aatgtaaatg ctttttcacc atattttttc cattcattat ttaattcttt tatcatacat
    17821 gagccagcac caagctgaaa tttgagagag ttaaatttgc tttttatatc attacttttt
    17881 ccaaggtaaa tctttttagt aatatcattt tttattatga atacacctgt gtcaaatttc
    17941 atttctttgt ataattgttt taattcacgt tttctatcca tgattttaga tacctctctt
    18001 tataattgat atgtaatatg taagtgtaaa aatatattac atatcaatta taaagagatt
    18061 aattttatat gtaaatagtt tttataaatt taattatgaa ttagtcatca ataaacaaga
    18121 aatttagctg tagaaatcca ttataaaggc tattataaat tttaatatgc taaaaatata
    18181 aaaagaatag ttgacagtgt agaaaatatg gaataaacta aaagtgtaat agtaatatta
    18241 aattatatat tacattgaaa ggtgtgaatg attattatga ataaaaaaat agaattaata
    18301 gggaattttg caagtgattg gattaggtat agtgattatg aatataaaat tactgaagaa
    18361 gatgaattat atatagttcc aacagaagat gctgtgttta ccatgtataa cccatttgat
    18421 gtagcagatg atataatagt agatataatt cgcataggac aagaggcatt acaagatata
    18481 tcaaaagaga caaaagaaat gaaactaaag aaagaaatac ttgaatttgt aaaaaagtat
    18541 ggattattgg gtttaatata ttcaagtgta tataatagag atatagttgg agaagaaaga
    18601 gtactgatga ttgaaaagaa ttatattaca aaagagaata tattgagtac agatgaatat
    18661 gtaaacatgt ttataccatt tgcaagtgat gaagatgtgt attttaaaaa gtatagaagg
    18721 ggtatagatg tatcaaagag agaagaatct ccaaagtttt ttggaaagag accattgatt
    18781 ttagatttag tattttcaaa gttctacact gaacaactag attggattgt aagttttgct
    18841 aaagatatgt gtaagcattt taatcaaatt tgtgtatata aaaatacatc taatctatta
    18901 actgaaagtg ttactattat gtctggaggg tttaatcctc aaaagatagg attttctata
    18961 agccaattag ataaaccaat tattgcatgg gagtttgatt ctttgaaaac agctattgag
    19021 actatctatg cctttgcaat tacaagtgaa ccttcttctt taaataaatg caagtactgt
    19081 ggtaaaattt atattcctac aaattctaaa tctcaatact gttcaccttc ttgtagaaat
    19141 tgctcaaatg taaagaaaag tagaagtaga gccaaaaaag ataaataaaa ttaataaata
    19201 tatcattgtt tagattttag taaataacta ctgaattaaa agttgttata taaaattata
    19261 tatctaaatg atggtatttt ttttgttgag aaaattgaaa agtttaattg agatagtaat
    19321 tttgagttga caaaaaccac ttttaacact actattataa gtggttggta aaataatata
    19381 tactaattca aatatagcat aaaaaacaaa aaaagtcaat ggaaaaaata aaaaaggaga
    19441 atttaaaaat gatatcacct attattttga gttctataaa tcagaattta aaggaaatag
    19501 aaagaaatga actgcttgaa actaatatag aatctggaga ttatggtcta gctctttctg
    19561 aatctgatgt aaaagatata ataaattcga gagataatac tttaaagggg tatggaagaa
    19621 tagaattaga tataaaagtt acaaaacagt taatagaaaa tatatataca tcacaatata
    19681 caaatgtgga caattattta gaggctatta atgatatgca agaaattttt tattatttaa
    19741 aaaatgaaac tgatgacaag atatgtgatg atgagattat agaaatactg ggtgattttt
    19801 atgaaaaatt ttcaggcaat atggacaatg taagaggaga agcagacgaa tttgcaaaga
    19861 aatttaaatt tggagaagtt taatatatga taggagagat tttgtatgtt aaataattta
    19921 agtaatatta atataaacga aaataattta ataaagaacc aatattccat atctctactt
    19981 aaggaatgtc taaattgtaa agtgatagat gaaagagaag tatataatat acaacaagaa
    20041 atatctctaa tacttatgga tttgattaaa aaatatacaa atggtcaaag cacatcagta
    20101 aaaacagaag ttgccgaaaa actgttgatt tcaatatggt atgctattga tgcatatata
    20161 aataagcttg gagatataga aaaaagagtt gtggagttga ctgctaagaa tgttaaaaaa
    20221 gtgtaccttg gaggaattga aatattagag gaagagttag ttaggctaaa agatttttat
    20281 aaactaatga tgagtagaaa attggatact aattcaatag catataatga taccttgatg
    20341 gagttatcaa gtttctttaa aagttatatt gtaaaatttg aagctcagga cgttccagta
    20401 agtatagatt atccattggc actagatgat atggatgtta agggtattta ttatgtgaag
    20461 aattatattg agagtataga tatagaaaat agattttgta acctatttaa gaaaaaagat
    20521 agagaaaaat tattttatga ctatggggtg acttataaaa tagattgtga tgttatactt
    20581 gtaaatttat ttgaacttat tatgaataat tgtatttttt ctactatttt aggaaatgaa
    20641 gtgactaatt tagaaatttc aaaatatgag tatgaatttt tagaaaaaca atttaaaaat
    20701 atgtacaata atattactga agataaagtt atagactctg aagaaagtaa tataattgaa
    20761 ttgattgaag tagatgatag ttttaacact gaagtagata gtaatttgga ttataatgat
    20821 tttgaagaaa ttaacagaga aattagaata aataaaaaaa taactttact acttatggaa
    20881 gcaattgaag tattaataaa aagattaagc atagaagatg aagatgtaat aagatatatt
    20941 aaaaaatatg aaaagatatt tattgaatct gtgctaagct caataaaaag taacactttt
    21001 aaaagtatgg taactgtgag taaaaataaa aatgaacact tagaagatta tattgttgat
    21061 gatgaaagta aattggatga tgaatcgttt agagagatat tcaatgagat attagatagt
    21121 acatctataa ttgaaaaaat aagaataata aaggaaaata tcaatgctaa aaaagacttt
    21181 atcgatattc ttgaatctga atgtttattt ggagaagagt atttaatgtt gtttgcatca
    21241 ttaagtgaat tagaattggc aatattgggt agtgtagtat tttatgaaga tattagaatg
    21301 agagaaatta atatattaga atttatgtta aatgagaaaa ctgaaactac tttatggaag
    21361 atagagtaca ttaaatttat gaagaggcaa agtgaagata agatatactc catagaagag
    21421 catatgaata aaattaatta acaaaaaatt gtgaataaat agaatgttag tatataatat
    21481 aatctgtaaa gcatatcaaa aatacatata tttggaggaa aattatgaaa gagtatatca
    21541 taaataatgt tgaagaaata agagaagaat taattgattt atctaagaaa atatgggaaa
    21601 atccagaatt agcctttgaa gaaaagtatg caagtagcat tcaaaaagaa tacctaaagt
    21661 caaaaggatt taaaattgaa gaagtagaaa atttacctac tggatttata gcaagttttg
    21721 gagagggtaa acctgtgatt ggcatacttg gagaatatga tgctttacca gaactatcac
    21781 aatgtgtaag tgcagaaaga aagccattgg tagaaggaaa agctggacat ggatgtgggc
    21841 ataacctgtt gggtgtagca ggtgtaggag cagttgtttc tataaaaaaa ttaatagaag
    21901 aaaataaatt taatggaaca ataaaatatt ttggttgtcc tgctgaagaa gaaggtggag
    21961 gaaagacagt tatgtgtata aatggctgtt ttgatgatgt agattgtgca tttacatggc
    22021 atccttttga tataaatgca ccttggagag gaggaagtct ggcaaactta tctgtaaaat
    22081 ttaaatttaa agggataaca gcccatgcag ctcaagctcc tcataatggt agaagcgcac
    22141 ttgatgctgt tgaaattatg aatgttggag ctaattattt gagagaacat gttattgact
    22201 ctataagaat gcactatgtt ataactaatg gtggtggaag acctaatgta gttcctggat
    22261 ttgctgaaag ttggtacttt attagaggta aaaaagcaaa agatgcagaa cacgttcttg
    22321 atagattaat aaaagtagct caaggagcag caatgatgac agaaactgaa atggagtata
    22381 aggttacaga tggaatatat gactatatac caaaccaatg tttgactgat ttagtttatg
    22441 acaatatggt ttttgttggt tgccctaaaa atactcctga agaagaagaa tttgcaaaaa
    22501 agttgtgtga tactcttact agagaagaaa gattaggtgt agcaacatca ttacaaaatg
    22561 ataaatctat tgtagaaagc tatatacaca aggaaatagt tgacggtgac aaagataaag
    22621 gactagctgg ttctactgat gttggagatg taagttatgt aataccagtg gctcaatttg
    22681 caatggcagc ttggcctgtt ggaattgcaa gtcatacatg gcagtcatgt tcatcagcag
    22741 gttcaaatat aggattttct gctatgataa attcagctaa agtactggct tgtagtgctt
    22801 atgatgtatt tatggatact aaaattattg atgaagcaaa aattgaattt gataaatcat
    22861 tagatggaca aaaatttaaa ccattggtat aattttggta ataaaatatt tcagggggga
    22921 atagctatga gagaaaaagt tgaaaaagtg cttgaggaaa agataaaacc agtattacaa
    22981 agagatggtg gagatgtaga gcttatagat gtaaatgaaa atggtgtggt tttagttaga
    23041 ctacaagggg catgtagtgg gtgtccagga gcgactatga caatcaaagc tattattgaa
    23101 aatgttttgg tgagtgaagt tccaggagta actcaagtat taggtgttta atagttagcg
    23161 tttattaaat gtatgttata cataagtatt taataaagaa gtaaaaaaaa tagtgaaaca
    23221 atatatatga aaaagtatga gaaagataat aaaacattat agaaataatg aaatatttca
    23281 tatgtatatg aagaaataag aaaaatagtg a
//
LOCUS       DAMKNB010000058        22842 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.060, whole genome shotgun sequence.
ACCESSION   DAMKNB010000058 DAMKNB010000000
VERSION     DAMKNB010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 22842)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22842)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22842
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.060"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            165..1001
                     /locus_tag="PC494_002494"
     CDS             165..1001
                     /locus_tag="PC494_002494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HDF3912985.1"
                     /translation="MNIKKIFNNNVVVSSLEDGTEIIVTGAGVGFKKKVGDLIDENLI
                     SKKYFVQDDQRDKYNQILNKTSIEYFKISEEIIEKANEVLNTQVNDSIILALTSHIEF
                     AVQREKQGIKLPNLILNETKQLYREEFEFGLWAIDEIEKRIGIKLPEDEAGYIAIHII
                     NGLENSQKDEGINILEFSKQVIQIIEEVHGFKLDVNSLNYTRLITHLKFFVQRILRKE
                     TYNDSDIEDMYKLVNKNYNKPKVCTEEIAALVLDRFEYKISKEEELYLMIHINKITNS
                     GC"
     gene            1354..2931
                     /locus_tag="PC494_002495"
     CDS             1354..2931
                     /locus_tag="PC494_002495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HDF3912986.1"
                     /translation="MKKNKLGLWNFFQMLGKTFMFPIALLSVSGMMLGLGAGFTDPKM
                     IEMVPFLGNEYVNLVLNFMLTIGLFAFNNLGALFAMAIPLGLLKKEKEFGAFSGLVGF
                     IAMHIGTNFYLTRADLLVPAEQMSTNGQAMIMGIQTYNTSVLGGIVAGLIVYAIYDKV
                     SNLKIPESLGFYSGPRLVPIVSLIVMSIVGLLIPIVWPPFFNAFQSLGRWISSAGPLG
                     YFSYAVAERVTIPFGLNHLVTSVFRFTPIGGTAVIDGETYFGTLNMFMAYVENNQIIP
                     LDLAGKMEQGKLMIQYGLAGAALAIYRTAKPENRKALKGLLISGVLTVIIGGISEPIE
                     FLFLFISPALFAFHTFMNGLANMVLPYLGVLMGFTGDLIAFISFGVLRGTATGWPIAV
                     LVAVLYFAIYYFVFKWAIIKFNIKTPGREDKEIKVSEGNGSNFKNLSTYKGQQMISAL
                     GGQSNILSLDNCVTRLRLKLQDVSLINEDAIKEAGGIAVVKLDEHTIQVIIGTQVYSL
                     RKQMDKAMEGHLEACND"
     gene            2924..4108
                     /locus_tag="PC494_002496"
     CDS             2924..4108
                     /locus_tag="PC494_002496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PatB family C-S lyase"
                     /protein_id="HDF3912987.1"
                     /translation="MINFDKKVDRLGTYCTQWDYVEDRFGKKDLLPFTISDMDLEFPF
                     EITEVLQERLNHRVLGYSRWKHDDFRNSVTNWYIKRFNCSVDSNWIYYSPSVMYSISK
                     LIEMLSNEGDGILINTPAYNAFYDVIINNNRNIIKSHLVNRNGFYSIDFNDFEKKCKK
                     SKIFILCNPHNPTGRVWSELELVKMIGICKNNDVKIISDDIHMDIVYDNRMTPILNVA
                     KDYLDSVFICTSASKSFNIPALTGSYVIIPNEGIRNKFENITRYRDFVNSPAILAILA
                     TMVCYDDCEYWLDELLKYLKENLKYTIDYIKDNLEPLKLVMPEGCYFAWIDFSELKIS
                     GEKFQKLLMDIGEVAIMSGSVYGEEGEFYLRLNVACSREKLEDGLNRIKKTMDYIEKR
                     IL"
     gene            4126..4725
                     /locus_tag="PC494_002497"
     CDS             4126..4725
                     /locus_tag="PC494_002497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HDF3912988.1"
                     /translation="MGYLKTMVDVMTTEMNAIRCLIDEAGIEYESIVSEIANCEGKVI
                     FMGVGKSAHIGKKLAATFASTGTPSFFVHATEAVHGDLGMIESKDITILISNSGNSME
                     VVNCIKYIKAIGSKTIAFTSNRNSVLAKECDYALIYPAKDEADHLNLAPTTSSTITLV
                     LGDSIACALSKSSNFGSSDFYKYHPGGSLGEKLKTANNG"
     gene            4749..5219
                     /locus_tag="PC494_002498"
     CDS             4749..5219
                     /locus_tag="PC494_002498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HDF3912989.1"
                     /translation="MFKMFKKKSIKSPISGKVIELSKIQDGVFSQKIMGEGVAIDSTG
                     DIVYAPINGKIVVVAETKHAFVIELENGMELLIHVGLDTVNLKGEGFEVLVSMGEQVK
                     EGTPMLKINRPLIESKGISLITPVTITNHSEYNMNTCNVGNSVEGGKDTVIEFK"
     gene            5578..6324
                     /locus_tag="PC494_002499"
     CDS             5578..6324
                     /locus_tag="PC494_002499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2087 domain-containing protein"
                     /protein_id="HDF3912990.1"
                     /translation="MKIENLSIDDIKRGYIFNDDLNCYSCIKCTKTYEVGEIYKIGNR
                     FFEASKAIELHMELEHSDYLEQLLNSDSKYNTLTENQKQLFQLFISDLPDKEIAKQVG
                     VSTSTIRHQKFIFREKAKQAKFYLALYESVFEDKSNKSSTIIPIHEHARMVDERYVVT
                     EEERKHILDTSFESMNPLKLKVFSSKEKKKVVILSKILEQFERGKKYSEKEVNQILES
                     IYDDFATIRRYLIEYGFMSRNKECTKYWLT"
     gene            6385..7059
                     /locus_tag="PC494_002500"
     CDS             6385..7059
                     /locus_tag="PC494_002500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase"
                     /protein_id="HDF3912991.1"
                     /translation="MNDELKSILYNKGVDIVRFVDISEFPINQTQGFSKAILFCIGLS
                     KKFITDIYNNLPTDSDEFLEKEEKVEELADWISKYIQNKGYRAYSQSEKNNLEHGYFE
                     KAYINPEMQSGISPLPHKTIANISGIGFMGKNNLFVTEEYGCAFSMCTVLTDAPISVE
                     RYPLIDSKCMDCNVCVENCPAKAIHGNEWTLPGKRESIIDVSKCFCVLRCMMSCPWSL
                     RYANQK"
     gene            7428..8774
                     /locus_tag="PC494_002501"
     CDS             7428..8774
                     /locus_tag="PC494_002501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 55 protein"
                     /protein_id="HDF3912992.1"
                     /translation="MEIETKTPDWINVLELNSKIDITGKYDVSNMIQNIVSDKSLEGS
                     IIYFPKGNYLFEKGIKISQQITLQGDSYYGRGNQVSNLDKKQSIIGTTNFITRGVSNM
                     SIITLSGTSQCIKNINFYYDSHDIEKIPPKNVSAITEYGETQGLSHFEHLFISGFSGI
                     GIEIPYYSTGNDITVSSCGLGMRLGEKSMLSSSKIYECKNGMEITTGVSLNNVRIEEI
                     KEIGINNKGFGFNLIMNLMVDQCGYCGFMFEKMCYSQITARITRCGQYYKSVDYNAYE
                     NMEDRKEEAYSIFYGDILENCNIVLMNRNIDTLESDSLNEHKIYVIKANETNNVMLTC
                     YAEADNFIQCAKGNLLLENGENTYKFYNGEICSVGGVQISDIDEKDLIKIIENTLYID
                     DKGKYLMVPRLKKNTVIYSVLDSTEEINKLHGGIWEQIDVKVLAGESMYYYKKIKD"
     gene            8801..10201
                     /locus_tag="PC494_002502"
     CDS             8801..10201
                     /locus_tag="PC494_002502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3912993.1"
                     /translation="MEESIIIKDISGWINVLDYGICNDETKDVSFKLQEIMDAVPEDS
                     IIYFPKGKYLFESGVKIKKRLTLCGDSYILANVPKNTAGVTQFTFKGKKNPKSENRAI
                     ITAKSVRHCIKNICFYSDSCDRDMTSNHEPPTDGKPRFHHNVIINYRNISAVICEDKQ
                     GEPGHYENLSFSGFSGIALDMPNNSTANDITIFTSGLGISTGENSTIANSKVWGCVDG
                     MIISTGTFINGMRVEEIKKVGIKNIGRGLNFITNITIDQCGYCGVWFDSISNVQISGN
                     ITRCGQYYYDVSYDNYLMLDNRVKEAYSLFYGNLLESSNIVLSNTNKDNWEDFKEDKH
                     KVYLVEALETKNVLLTCNIDATDWIVKSEKGNLTYNNMRQTVIFYDGKLSSINGIGIS
                     DEDYGDKVKIKKGNIYINSKDKDIKMHKPEVGDIMSTIIKDKSILSAHYGGTWEKIGE
                     KIEFGITVHYYKLIEK"
     gene            10411..11847
                     /locus_tag="PC494_002503"
     CDS             10411..11847
                     /locus_tag="PC494_002503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 55 protein"
                     /protein_id="HDF3912994.1"
                     /translation="MEGRTGIKDGRWINVVERGIKNDGSYNIGPALQDIIDEIETDFC
                     VLYFPKGKYLFTSGVKINKEIVLQGDSNSSTGTTQFITRGVENMSIITLTGKKQCIKN
                     INFYSDSCEIQVNKEPPTKGNPKYHYEMIINKNEKNVEMNNVSAILYDNSKNMIKGLG
                     HYENIYISGFSGTGIRIPYYSIVNDITVSSCGLGIDTGIDTIISNSRISKCQNGMRIR
                     TGTSINNVRIEKIQKVGLISSQVKDYEGYGSYKINNITIDQCGYCGFLFDSVKGSYFS
                     GIIRRCGQYYYNTDYDTYLSIKDRVEEAYSLFYGNYFTECNIDLVSDNKDNWDDGLEY
                     KHKVYVFKTLQIPKLTLRCNIDAYDYIVKSVHGGGNLMLKNNFNNYIFIDSSNPEVIN
                     GINFNYQKNGNLLRLNNGKLSYKNGKEETAIFRPNYGLIVASTDSECEQIETSYGGKW
                     EKLGSEVIGKETVYYYKHHEPDKTNQIQ"
     gene            12191..13135
                     /locus_tag="PC494_002504"
     CDS             12191..13135
                     /locus_tag="PC494_002504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1848 domain-containing protein"
                     /protein_id="HDF3912995.1"
                     /translation="MIVSVSRRTDIPAFYSKWFFNRLKEGFVYVINPMNPKQVSKIEL
                     NPHTVDCFVFWTKDVTPMLYDLNKLKDYKYYFHYTITSYGKEVETCILDKRKVIDSFK
                     ELSRKIGKERVILRYDPIFLSEKYTVDYHIKAFASLCNQLDGFTEKCIISFIDLYKKT
                     KFNTKALHIKPIEITEIETLSKEISKIAHKHGIILEMCSEEYNLSKFGIGKSKCIDDR
                     LISKIIGCEVEVKKDSTQRDICGCVKSVDIGQYNTCRHYCLYCYANFNYAKVEENCRL
                     YKEDNKLLIDTLRDDAKISIRDMKTIKVDKNKQISIFD"
     gene            13304..14236
                     /locus_tag="PC494_002505"
     CDS             13304..14236
                     /locus_tag="PC494_002505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HDF3912996.1"
                     /translation="MNLLKKYPIPIASLILSIFTLGNLLQSYSESLRNVIGFIGFILY
                     AIYIVKIILLRKGVKEQLENPLISSTFPTITMATMIFATYIKPLSLELSIMIWSIGIV
                     GHLVLIVLFSKKFLVKFSIKTVFPSWYIVYVGIVAASVTAPAFNQLLIGKIAFWIGFV
                     SYIVLIPVILKRVWIIKEMPEPSLPSIAILAAPGSLLLSGYINSFSDKNNVVLYLLFI
                     LSIVFYIIVLGYLPKLLRLPFYPSFAAFTFPMAISAMGMKLMNGYLTKSGHFISWISY
                     ASKLEEIIATVIILYVLVLFIIYLSKSETTSKVK"
     gene            14341..14808
                     /locus_tag="PC494_002506"
     CDS             14341..14808
                     /locus_tag="PC494_002506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C_GCAxxG_C_C family protein"
                     /protein_id="HDF3912997.1"
                     /translation="MKTKEEYLKEVRNISEEYFRKGEFFCSEAVLQTINDALGQPLSP
                     EITKLASGFPIGLGKAQCLCGAISGGEMALGIVYGRVHGEAMNPKMFEHAKGLHDYIK
                     KEYGATCCRAITKKWDGDNFMSPERKEHCIKITGQVTEWVADKLIEDEKLNIK"
     gene            complement(15052..15906)
                     /locus_tag="PC494_002507"
     CDS             complement(15052..15906)
                     /locus_tag="PC494_002507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009912760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar uptake protein"
                     /protein_id="HDF3912998.1"
                     /translation="MLTIIIALLPVMGWGLMPIVANLKKSSPHEQLLGTSISAFIFST
                     IITLVIHPEITFFSFCISMISGIFWSLGQLMQFKAIQIASVSKVMPISNGSQLTFTTL
                     LAVILFNEWTSSKMLLIGSLSILCIILGILLTNYQTKKSTDKNMLKCVGVVLLSSLFL
                     SLYVVTNQIFLIEGYRIILPQSVGMLITSSIIVKYFSKEIVYMENVLFNLITGILWSI
                     ANLGMFITTNTLGVTISFSISQSCVIVATLGGIIFFKEKKNKKEWLAIFIGIILIMSG
                     VFMLSIIK"
     gene            16072..18036
                     /locus_tag="PC494_002508"
     CDS             16072..18036
                     /locus_tag="PC494_002508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HDF3912999.1"
                     /translation="MLTDMIQNREIKIIKFLLKEGHTTVKAIADDLDVSEKTVSKSLK
                     EVEAVLKKIGLSLIRKPKIGVYIDGDLKKILPYLDNKGSQIPTTREERVIYIYSVLLK
                     SNDYITIQQLSDELYISRGTIERDLAEVEKLLKNEGISIYKKPSKGIKLNISERDKRQ
                     LTAKFIHKFWSRNWYIKQEQESFYQAFEKIQADVNGIFSEDDLSIIIDILRNFSRERK
                     FEFSDYEFQSLVIHLAIAVERIRKGEYIEESLYTGNIENNQMSNTNYLAKQLEEKFSI
                     LLPKSEIGYINLHLVASDQHRDTNELKNTSTNPCETSTNNISNLREIIKNTLYETAYD
                     KDLIDGLTSHVHSSINRLKYGLSIKNPYVNTIKQNFSLSFEQALDLKKVIEFIYDIRI
                     NDDECAYIALHFEAFRERMKELPQNIRVILVCSTGLGSSRLLSARIKKYFPMIKIEKV
                     LSVQELVSSKIDADLVISTIYLELETIPTIVVSPILNESDIRTLERNIQNVSSYTSKK
                     YKSFRNLIFEENILLNIEASNYEDAIKYITDNLIKKGFAKEGIAKSAIERENLSYTSF
                     QSIATPHANPSYIKKSNISVATLKNPITWGNEKVEVIFFISLENDKNLELDEIYEVFY
                     DFIDNKKNINDILSATSTKEVYDLLVEESI"
     gene            18036..18497
                     /locus_tag="PC494_002509"
     CDS             18036..18497
                     /locus_tag="PC494_002509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDF3913000.1"
                     /translation="MKISDVLKKEQIVFNLDTNTKEETIKKLSSIFVENGIVDNEEEY
                     VKSVLEREEHSTTGIGNGIAIPHGKSNAVKKSSIIFAKTKHKIEWDALDEKPVDSIFL
                     LAISNIDKDSNHLVLLSKLATKLMDDDNVDALKLANSEQEIINIFSEEGEM"
     gene            18500..18820
                     /locus_tag="PC494_002510"
     CDS             18500..18820
                     /locus_tag="PC494_002510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HDF3913001.1"
                     /translation="MKRKIIAVTACATGVAHTYMAAQALKKASKKMGHLIKVETQGAT
                     GIDNELTTKDAQIAEVVIFAVDTKVRNAERFEGKEILEVPVNAPIKDAEKVINDALKL
                     IDTK"
     gene            18836..19936
                     /locus_tag="PC494_002511"
     CDS             18836..19936
                     /locus_tag="PC494_002511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HDF3913002.1"
                     /translation="MLKKIVSELKKHVLTGISYMIPLVIAGAMIMAISRVGGSFYNIP
                     DIWDAKYAESASSIVRLLHDLDGFGGTALGLMFPVIAAFIGFSIADKLAIVPGLVGGM
                     IAKDIGAGFLGALAVGLIAGYTCLFIKNHVKLPKSAASIVPIFIVPVFGTLITVVLIN
                     YVIGIPFATLNTGLENWLNGLSGTNQILMAAIIGAMMAVDLGGPVNKAALTTSLALLT
                     SGIYAPNTAAMVGIVIPPLGLGLATILAKQKYNKQLREAGKSSLIMGLIGVSEGAIPF
                     AVESPLKVIPSCVIGTAIASAMAVGLGSVNATPISGFYGWFTVENWPMYVLSIAVGTV
                     IVAGLVIVLRGNPVIEDDEFEDDDFDEAEWES"
     gene            20056..22656
                     /locus_tag="PC494_002512"
     CDS             20056..22656
                     /locus_tag="PC494_002512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HDF3913003.1"
                     /translation="MIKAHIVNHTHWDREWYFTSGDALVLSEQLFTDVIDELERNPDV
                     SFVLDGQLSILDDYVQLHKEKIEIIKKLIKEDRLHIGPWFTQTDAFFARGESILRNLM
                     IGIFESKKYGKYMKIGYLPDTFGFNAQMPILLKHVGLDNIFFWRGIHLGKQVQSPYFK
                     WKSLNGESYIYAVNMPHGYGTGMLLEPSLKYVNGRLDPAIDFIKSYTDVDEVLIPSGN
                     DQLNIIGDFKNKIKAINDIGKYSYITSSYQEFLKYIKSIESLESYRGEFREPVLARIH
                     KSIGSSRMDIKLACDKLENKLIKRIEPLLVIAKKSKIEISNQLLINTWKKLLEGQAHD
                     SLAGCVTDTVTDDILHRIREANEICDSIENTIVKKISEGLKLSKNDILVFNTEAKRFN
                     GYKEIQVVSDSKNIYFKDNLDATIIEETYVKPRENVLEETPAGNIFIEEPGYYILKVR
                     INIQLPALGYKVVSFELSDKEMVSLDKSNDTFISNDNYKIIYEDGSLNLQLKDGTYIS
                     NFLTLKDSGNAGDTYDFSPLKNDEDIKLSFDKVYTEKALGYEKMVVKGTTLLPLTLED
                     RKNKYLKGKLNVKVSIVLSKENPLMDVKLCVDNTIYNHRLRVHIKTDIKDNKNIASLP
                     FGYITRKNGVLDNWEDIYSEMPIDLEPLESNITLTNQNRSCTVFTRGIKEYQHIEDEI
                     ALTLLATTDELGKPDLLYRPGRASGDTTKKGHIRIKTDKAQMLKELEFSFAIYMDSKS
                     FDELEIANLTHNYLRECVNYQLQDYNFFLYRIDNKIQKSIVNKTVSRELEIISLPENY
                     LISACYPSYYSKDKFIIRVENPSSNRMILDEQIFKNRNGKIVNAIEDVEEEQVYEIAP
                     FDVISILLDL"
BASE COUNT         8972 a         2354 c         4038 g         7478 t
ORIGIN      
        1 aatatgacaa attaattgat gacaataaaa aatattttgt tattgtagta ttatagggta
       61 aattgcaaaa tatatacgaa agtaaaattt taaatattga cattaaatta aatatactat
      121 actatgtaag tgtgatgaga gaattttttt agaggggatt tatagtgaat ataaaaaaga
      181 tatttaataa caatgtagta gtaagctccc tagaagatgg cacagaaata attgtcactg
      241 gtgctggagt aggatttaag aaaaaagtag gcgatttgat agatgaaaat ttgatttcta
      301 agaaatattt tgttcaagac gatcaaaggg acaaatacaa tcaaatactt aataagacct
      361 ctattgaata ctttaaaatt tcagaagaaa ttatagaaaa ggctaatgaa gttttaaata
      421 ctcaagtgaa tgattcaata atattagcct taactagtca catagaattt gctgtccaaa
      481 gagaaaaaca aggtataaaa ttaccaaact taatattgaa tgagacaaaa caactttata
      541 gggaagaatt tgaatttgga ttatgggcaa ttgatgaaat tgaaaaaagg ataggaataa
      601 aattgcctga agatgaagca ggatatattg ctattcacat aatcaatggt ttggaaaatt
      661 ctcaaaaaga tgaaggtatt aatatactag agttttcaaa acaagttatt cagataattg
      721 aagaagtaca tggatttaaa ttggatgtaa attcattaaa ttatactaga cttataactc
      781 acttaaagtt ttttgttcaa aggattctcc gaaaagaaac ttacaatgat agtgatattg
      841 aagatatgta taagttagtg aataaaaatt acaataaacc taaagtgtgt actgaagaaa
      901 ttgcagcatt ggtattagac agatttgaat ataagattag taaagaagaa gaattatatt
      961 taatgattca cataaataaa ataacaaaca gtggttgtta ggattgtaac tgataaagca
     1021 ggcaaaacct aagtcattga gcttaactat tagattaagt tttttgattt aggttttttt
     1081 attagataca atcaaaatac agacagtgac ttttaggatt gtaactggtt aagcaggcaa
     1141 aacctaaatc attgaattta actattaggt taagtttttt gatttaggtt tttttattag
     1201 atacaatcaa atacagacag tggttgttag gattgtaact ggttgagcag gcaaaaccta
     1261 aatcattaaa cttaattatt aaattaagtt ttttgattta ggtttttcta taaatttgat
     1321 tatgttttta gataaaaata ggaggggaaa attatgaaaa aaaataagtt aggtttatgg
     1381 aacttcttcc aaatgttagg aaaaacgttt atgttcccaa tagcactact tagtgtttct
     1441 gggatgatgc taggacttgg ggcaggtttt acagacccta agatgattga aatggttcca
     1501 tttttaggga atgaatatgt taacttagtt ttaaacttca tgttaacaat aggattattt
     1561 gcatttaaca acttgggagc attatttgca atggcaattc cactaggatt attaaaaaaa
     1621 gaaaaagagt ttggtgcttt ttcaggatta gtaggattta tagcaatgca tataggtaca
     1681 aatttttatt taacaagagc tgatttgtta gtaccagcag aacagatgtc aactaatggt
     1741 caagctatga ttatgggtat acaaacatat aatacaagtg ttttaggtgg tattgtagca
     1801 ggattaattg tttatgcaat atatgataaa gttagtaatt taaagatacc agaatcatta
     1861 ggattctaca gtggaccaag attagttcca attgttagtt taatagttat gagtatagtt
     1921 ggattattaa tacctattgt ttggccacca tttttcaatg cattccaaag tttaggaaga
     1981 tggatttctt cagcaggacc attaggatat ttttcatatg cagtggcaga aagagttaca
     2041 attccatttg gactaaatca tcttgtaaca tctgtattcc gttttacacc aataggtgga
     2101 actgctgtta ttgatggaga aacgtacttt ggtacattga acatgtttat ggcatatgta
     2161 gaaaataatc agattatacc tcttgattta gctggtaaaa tggaacaagg taaattgatg
     2221 attcaatatg gattagctgg tgctgcattg gctatctacc gtacagcaaa accagaaaat
     2281 agaaaggcac ttaaaggact tttaatatca ggagtgttga cagttattat aggtggtata
     2341 agtgaaccaa tagagtttct attcttattc atatcaccag cattatttgc tttccataca
     2401 tttatgaatg gtctagcaaa catggtactt ccatacttag gcgtgttgat gggattcaca
     2461 ggagatttaa ttgcatttat aagttttggt gtgttaagag gaacagctac aggatggcca
     2521 atagcagtat tagtagcagt tttatatttt gcaatatact attttgtatt taagtgggca
     2581 attattaagt ttaatataaa gaccccagga cgtgaggata aagaaataaa agtatctgaa
     2641 ggaaatggtt caaatttcaa aaatttgtct acatataaag gacaacaaat gatatctgct
     2701 ttaggtggtc aatctaatat attatcacta gataattgtg taactagatt acgtttaaaa
     2761 ttacaagatg tatcattaat aaatgaggat gcaattaaag aggctggtgg tatagcagtt
     2821 gttaaattgg atgagcatac aatacaagta attataggaa cccaagtgta ttctttaaga
     2881 aagcagatgg ataaagctat ggaaggtcat ttggaggcat gtaatgatta attttgataa
     2941 aaaagtagac cgattgggta catattgtac ccagtgggac tatgtagaag atagatttgg
     3001 taagaaggat ttgcttcctt ttacaatttc agatatggat ttagagtttc catttgaaat
     3061 aacagaggtg ttgcaggaaa ggttaaatca tagagttttg ggatacagta gatggaaaca
     3121 tgatgatttt agaaattcag ttacgaattg gtatattaaa agatttaatt gtagcgttga
     3181 tagtaactgg atatattata gtccaagtgt aatgtattca attagcaaac ttattgagat
     3241 gttaagtaat gaaggagatg gaatccttat aaatactcct gcatacaatg ctttttatga
     3301 tgtgataata aataacaatc gtaatattat aaagtcacat cttgtaaata ggaatggatt
     3361 ctattcaatt gattttaatg attttgagaa aaagtgtaaa aaatctaaga tatttatttt
     3421 atgtaatcct cacaatccaa ctggtagagt atggagtgag ttagaacttg ttaagatgat
     3481 aggaatttgt aagaataatg atgtcaagat aatatcagat gatatacaca tggatattgt
     3541 atatgacaat agaatgacac ctatcttaaa tgttgcaaag gactatttag attctgtatt
     3601 catttgtaca tcagcgtcta aatctttcaa tataccagca ttgactgggt catatgtgat
     3661 tataccaaat gaaggtatta gaaataaatt tgaaaatatc actagatacc gtgattttgt
     3721 aaattcgcca gcaattctag caatattagc cacaatggtc tgttatgatg actgcgaata
     3781 ttggttagat gaactattaa aataccttaa agagaatctt aaatatacga ttgattatat
     3841 aaaagataat ttagaaccat tgaaattggt catgccagaa ggctgttact ttgcttggat
     3901 agatttttcc gaacttaaaa taagtggtga gaaattccaa aaattattga tggatattgg
     3961 agaagttgct attatgtcgg ggtctgtata tggtgaagaa ggtgagtttt atttaaggtt
     4021 aaatgtggca tgttcaagag aaaaacttga agatggttta aataggatta aaaaaactat
     4081 ggattatatt gaaaaaagaa ttttatagta ggaagggaga tagttatggg atatttaaaa
     4141 acaatggttg atgttatgac tactgaaatg aatgccataa gatgtttaat agatgaagca
     4201 ggaatagaat atgaaagtat agttagtgaa attgcaaatt gtgaaggcaa agtaattttt
     4261 atgggtgtag gaaaatctgc acatataggt aagaaattgg cagctacatt tgctagtact
     4321 ggtacaccta gcttttttgt acatgcaaca gaggcagtgc atggagattt aggaatgatt
     4381 gaaagtaagg atattacaat tttaatatca aatagtggaa attctatgga agtggtaaac
     4441 tgtataaaat atattaaagc aataggttct aagacaattg catttacttc aaacagaaat
     4501 tcagtactgg caaaagagtg tgattatgct ttaatatatc ctgcaaagga tgaagcagac
     4561 catttaaatc tagcaccaac aacatcatct acaattactt tggttttagg agattctatt
     4621 gcatgtgcat tatctaagag tagtaatttt ggttcttcag atttttataa gtaccatcca
     4681 ggaggaagtt taggtgagaa gttaaaaaca gctaacaatg gataaaagca aaaaggagag
     4741 tagtttttat gttcaaaatg tttaaaaaaa aatcaataaa atcacccata tcaggaaaag
     4801 taatagagtt atctaaaata caagatggtg tattttctca aaaaattatg ggagagggtg
     4861 tagctataga ttctacagga gacattgtat atgctccaat caatggaaag atagtagtag
     4921 tagcagagac taaacatgca tttgtaatag aattagaaaa tgggatggaa cttcttattc
     4981 atgttggttt agatactgta aatttaaaag gcgaaggttt tgaggtattg gtgagtatgg
     5041 gagaacaagt gaaggaagga acaccaatgt tgaaaattaa ccgtcctttg attgaatcaa
     5101 agggtatatc acttattact ccagttacaa taactaatca ttcagagtac aatatgaata
     5161 catgtaatgt aggcaatagt gttgaaggtg ggaaagatac tgtaattgag tttaaataaa
     5221 gaactaaaat acaaggttaa tatttataaa tacctataaa cttatgtttt ataagattga
     5281 ttgtatagat ttgttgtata aaaaagaact ctttaattat aaattaagga gttctttttt
     5341 attttgtaaa tattgtttag atttatatag aaaaacactt agtaataaat agaataaata
     5401 agtatttata tagctaaaaa tctaaatagt tttgtttaaa tatattttta tattttgtaa
     5461 tttcaaatta ataaataatt agatttgata aataaaaaat aaaaatgttg attacattaa
     5521 taaactttaa tataatatat ttatgaaaaa tgtaaactgt gaaatggagg tagtaacatg
     5581 aaaattgaaa atctttctat tgatgatatt aaacgaggct atatatttaa tgatgattta
     5641 aattgttata gttgcattaa atgtacaaaa acatatgagg taggagaaat atataaaata
     5701 ggtaatagat tctttgaagc ttcaaaagct attgaacttc atatggaatt agaacatagt
     5761 gattatttag agcaattgct taatagtgat tcaaagtaca acacattgac tgaaaatcaa
     5821 aaacaattat ttcaattatt tattagtgat ttaccagata aggagatagc aaaacaggtt
     5881 ggagtatcca catctactat acgccatcaa aaatttattt tcagagaaaa agcaaaacag
     5941 gctaagttct atttagcact atatgaatct gtatttgaag ataaatctaa taaaagtagt
     6001 actataatac caatccatga acatgctcga atggtagatg aaagatatgt agtaactgaa
     6061 gaagagagaa aacacatttt ggatacatca tttgaaagta tgaatccttt aaaattaaaa
     6121 gtattttctt caaaagaaaa gaaaaaggtc gtaattttat ctaagatttt ggaacaattt
     6181 gaacgtggga agaaatattc agaaaaggaa gttaatcaga ttttagaatc tatatatgat
     6241 gattttgcaa caattagaag atatctaatt gagtatggtt ttatgagtag aaataaagaa
     6301 tgtacaaaat attggttaac ataattaaaa taataaattt tactaatgtg taatgttatt
     6361 tttatctagg gggaggagtc aaatatgaat gatgaattaa aatctatttt atacaataaa
     6421 ggtgtagaca ttgttcgctt tgttgatata tctgaatttc caataaatca aacacaaggt
     6481 ttttctaaag caattttatt ttgtataggg ttatcaaaaa aatttattac agatatatac
     6541 aataacttac ctacagatag tgatgagttt ttggaaaaag aggagaaagt agaagaatta
     6601 gctgactgga tttcaaaata tattcaaaat aaaggatata gagcgtattc tcaatcggag
     6661 aaaaacaatc tagaacatgg atattttgaa aaagcctata ttaatccaga aatgcaatca
     6721 gggattagtc ctttaccaca taagacaata gcaaatatta gtggcattgg atttatggga
     6781 aaaaataatt tgtttgtaac agaggaatat ggatgtgctt ttagcatgtg tacagtactt
     6841 acagatgctc caatttctgt tgaaagatat cctttgattg attcaaaatg tatggattgc
     6901 aatgtttgtg tagagaactg tcctgcaaaa gctatacatg gaaatgaatg gactttacct
     6961 ggaaaaagag aatctattat tgatgtttca aagtgttttt gtgtattgag gtgtatgatg
     7021 agttgcccat ggtcattaag atatgcaaat caaaaataac tttactagag aaggtattaa
     7081 attgaatatt ataaaatttt taaaatgtaa gattatataa gatttttcaa aataaaaatt
     7141 tgtatagaac actcagaaat gagtgttttt ctattgggat taaattatat tgatacaaag
     7201 cttaactatt ttaatcatta tataaaattt gtattaaaaa attaagaata acttggtaat
     7261 agtgaaaata taatgagatt ataattgatt tataatataa ctataatgat attgtaaaaa
     7321 tgaaaattgt cctctcaaaa ttcccaaaga gagtaaaagt cacttcagtt atagtcaaaa
     7381 aaatttttct gtgaaaagaa tttagatttg aaaaggagga attaatcatg gaaattgaaa
     7441 ctaaaactcc agattggatt aatgtactag aattaaacag taaaatagat attactggga
     7501 aatatgatgt aagtaatatg atacaaaata ttgtctctga taagtcacta gaaggttcca
     7561 ttatatattt tccaaaaggt aattacttat ttgagaaagg tattaaaatt agtcaacaaa
     7621 taacacttca aggagattct tattatggaa gaggtaatca agtatcaaat ttagataaaa
     7681 aacaatcaat cataggaaca accaatttta taacccgagg agtttctaat atgagtatta
     7741 ttacattgtc aggaacaagt caatgtatca aaaatattaa tttttattat gatagtcatg
     7801 atatagagaa aataccgcct aaaaatgtat ctgctattac agaatatgga gaaacacaag
     7861 gactatctca ttttgaacat ctgtttattt ctggattttc agggatagga attgaaattc
     7921 catactattc aactggtaat gatattactg ttagttcatg tggtcttggt atgaggcttg
     7981 gagagaagtc aatgctttct agtagcaaga tttacgaatg taaaaatgga atggagatta
     8041 ctactggtgt tagcttaaat aatgtgagaa tagaagaaat aaaagaaata ggtattaata
     8101 ataaaggatt tggttttaac ctgattatga atcttatggt tgatcaatgt ggatattgtg
     8161 gatttatgtt tgaaaaaatg tgctatagcc agataactgc cagaattact agatgcggtc
     8221 agtattataa aagtgttgat tataatgctt atgagaatat ggaagatagg aaagaagaag
     8281 cttattccat tttttatgga gatattttag aaaattgcaa tattgtattg atgaatagaa
     8341 atattgatac cttagaaagt gattcactta atgaacataa gatatatgta atcaaggcaa
     8401 atgaaacaaa caatgtaatg ctaacatgtt atgctgaagc agataacttt atacaatgtg
     8461 caaagggcaa cttgctgtta gaaaatggtg aaaatactta taaattttat aatggtgaga
     8521 tttgttctgt aggaggtgtt caaatttctg atatagatga aaaagattta atcaaaataa
     8581 tagagaacac tttgtatata gatgataaag gtaagtattt aatggttcct agattaaaaa
     8641 agaatactgt aatatattca gtactagatt ctacagaaga aataaataaa ttacatggtg
     8701 gaatatggga acagattgat gtaaaagtat tagctgggga atccatgtac tattataaaa
     8761 agataaaaga ttaaattatc aaactaggag gtagtgatta atggaagagt ctataataat
     8821 taaagatata agtggctgga ttaatgtact tgattatgga atttgtaatg atgaaacaaa
     8881 agatgtaagt tttaagttgc aagagattat ggatgctgta ccagaagatt ctattatata
     8941 ttttccaaaa ggaaaatact tatttgaaag tggtgttaag attaagaaac gattaacctt
     9001 atgtggagat tcttatattt tagcgaatgt tcctaaaaat actgctggag taacacagtt
     9061 tacttttaaa ggaaagaaaa atcctaaaag tgaaaataga gcaatcataa cagcaaaaag
     9121 tgtaagacac tgtattaaga acatttgctt ttattcagat agttgtgata gagatatgac
     9181 atctaatcat gaacctccaa cagatggaaa acctagattt catcataatg taattataaa
     9241 ttatagaaat atatctgctg ttatatgtga agataaacag ggagaaccag gtcattatga
     9301 aaatctatct tttagtggtt tttctggaat tgcacttgat atgcctaata attctacagc
     9361 aaatgatatt acaattttta catccggact tggaattagt acaggggaaa attcaacaat
     9421 tgctaacagt aaggtttggg gctgtgttga tggaatgata atttctactg gaacttttat
     9481 aaatggtatg agggtagaag aaataaaaaa agttggaatt aaaaatattg gtagaggttt
     9541 aaattttatt acaaatatca caattgacca atgtggatat tgtggagttt ggtttgattc
     9601 tatatccaat gttcagatat caggaaatat cacaaggtgt gggcagtact attatgatgt
     9661 aagctatgat aattatttaa tgttggataa tagagttaaa gaagcatatt ctttattcta
     9721 tggtaattta ttggaatcaa gtaatatagt tttatcaaat accaataaag ataattggga
     9781 agatttcaaa gaagataagc ataaggtgta tcttgtagaa gcacttgaaa ccaagaatgt
     9841 actattaaca tgcaatatag atgctactga ctggattgtt aagtcagaaa aaggaaattt
     9901 aacgtacaat aatatgcgac aaactgttat attttacgat ggaaaactaa gtagtatcaa
     9961 tggaattggt atatctgatg aagattatgg ggataaagtc aagataaaaa aaggaaatat
    10021 atatataaat agtaaggata aggatattaa gatgcataaa ccagaggtag gtgacattat
    10081 gtcaacaatt attaaagata aaagtattct ttctgctcat tatgggggaa catgggagaa
    10141 aattggtgaa aaaatagagt ttggaataac tgtacactat tataaattga tagagaaata
    10201 agtaaatacg tagtatttga atagatgtat tttattggag agctaggact atagttttaa
    10261 tgtaaatggt ttggtaatag catggattga ataatataaa aataatataa aaaattaatt
    10321 tgattatgta aaattctatg aagtagtaaa actgtgactt tagtcatagg aggttcaaac
    10381 taagtaaaag ggaaaggaat atataatatt atggaaggaa gaactgggat taaagatgga
    10441 agatggatta atgtagtaga aagaggtatt aaaaatgatg gttcgtacaa cataggtcct
    10501 gctttgcagg atattattga tgaaatagaa acagattttt gtgtcttata ttttccaaaa
    10561 ggtaaatacc tatttacaag tggtgttaaa attaataaag aaattgtatt gcaaggtgat
    10621 tctaattcat ctacaggtac tacacaattt ataactcgtg gagtagaaaa tatgagtatt
    10681 attacattga cagggaagaa acaatgtatt aaaaatataa atttctattc tgatagttgt
    10741 gagatacagg taaataaaga accaccgaca aaaggtaatc ctaaatatca ttatgagatg
    10801 attatcaata agaatgaaaa gaatgttgag atgaacaatg tatcagcaat cctgtatgat
    10861 aacagtaaga atatgattaa aggtctaggc cattatgaaa atatttatat aagtggtttt
    10921 tcgggtacag gaattaggat accatattac tcaattgtaa atgatattac agtttcatct
    10981 tgtgggctgg gtattgatac aggaatagat acaattattt ctaatagtag aatatctaag
    11041 tgtcaaaatg gaatgaggat taggactgga actagcataa ataatgtaag aattgaaaaa
    11101 atacagaaag ttggtcttat aagtagtcaa gttaaggatt atgagggata tggaagttat
    11161 aaaattaata atattacgat tgaccaatgt gggtattgtg gttttttatt tgactcagtg
    11221 aaaggtagtt atttttctgg tattataaga agatgtgggc agtactatta taatacagat
    11281 tatgacacat atttaagtat taaagataga gtagaagaag catattcttt attttatgga
    11341 aattatttta cagaatgtaa tattgattta gttagtgata acaaggataa ctgggatgat
    11401 ggcttagaat ataaacataa agtttatgta tttaaaaccc ttcaaatacc aaaattaaca
    11461 ttgagatgca atatagatgc ctatgattat atcgttaaat cggtacatgg aggaggtaat
    11521 ttaatgttaa aaaataactt taacaattat atatttattg attcatctaa tccagaagtt
    11581 attaatggaa ttaattttaa ttatcaaaag aatggaaact tgttaaggtt aaataatggt
    11641 aaattaagtt ataaaaatgg aaaggaagaa acagctatat tcagacctaa ttatggtctt
    11701 attgtagcat caacagattc agaatgtgaa caaatagaga ctagctatgg aggaaaatgg
    11761 gagaagcttg gttctgaagt aattggaaaa gaaacggtat attattacaa acatcatgaa
    11821 ccagataaaa caaaccaaat acaataaaat ttgtattata taatgatata aagttttaat
    11881 atatagtgtt tatctttaat gtaatattgg tatatttgta tagtattaaa tttgttaaaa
    11941 agtaaaattg tagggtgctt gaaaatagca ccttttttag tttcattata aaattagttt
    12001 tgaaagttta ggaataatgt atatttattt ttaaagaatt ataaccttat taaggatatt
    12061 ttaaatgcta gaaatgaatc agtaaatcat actggaatta tcttaaatgt tttgattaaa
    12121 ttaagtattt agagctataa ttatattaaa aatatattag aacataatta tattactatg
    12181 gaggttaaat atgatagtaa gtgtgagtag aagaactgat atacctgctt tctatagtaa
    12241 gtggtttttt aacagactta aagaaggttt tgtttatgta attaatccaa tgaatccaaa
    12301 acaggttagt aagatagagt taaatccaca tactgttgat tgttttgtat tttggacaaa
    12361 ggatgtaact ccaatgttat atgatttaaa taaattaaaa gactataaat attattttca
    12421 ctatactata acatcatatg gaaaagaagt agagacatgt attttagata aaagaaaggt
    12481 aatagattca tttaaggaat tgtctagaaa aataggcaaa gaaagagtaa ttttaagata
    12541 cgacccgatt ttcttaagtg aaaagtacac agtagattat catatcaaag catttgcgag
    12601 tttatgtaat cagcttgatg gatttacaga aaaatgtata ataagtttta tcgatttgta
    12661 taagaaaaca aaatttaata ctaaagcatt acatataaag ccaatagaaa ttacagaaat
    12721 agaaacatta tcaaaagaga tttctaagat tgctcataag catgggataa tacttgaaat
    12781 gtgttctgaa gaatataatt taagtaaatt tgggattgga aaaagtaagt gtattgatga
    12841 tagattaata tcaaaaatta taggatgtga agtagaggta aaaaaagata gtacacaaag
    12901 agatatttgt ggatgtgtta aaagtgtcga tataggacaa tacaatactt gcagacatta
    12961 ttgtctgtat tgttatgcta actttaatta tgcaaaagta gaagaaaact gtaggcttta
    13021 taaggaagat aataaattac tcatagatac tttaagagat gatgcaaaaa taagcattag
    13081 agatatgaag actattaaag tagataagaa taaacaaatt agtatatttg attaaaataa
    13141 atatactaat taccttaata tattaagaat atagatactt ttgataataa aattaaactt
    13201 aatagatatt ttctatataa gaaagatggt cataatatgt caatttgacc atctttttga
    13261 tataattaaa acacaaataa tttagtaaca aaggaggcag aacttgaatt tattaaaaaa
    13321 atatcctata cctattgcaa gtttgatttt gtcaatcttt actttaggta acttattaca
    13381 atcttatagt gaatcattac gtaatgtaat tggatttata ggatttattt tgtatgcaat
    13441 ttatatagtc aaaataatat tacttagaaa gggtgttaaa gagcaattag agaacccttt
    13501 aatatcaagt acatttccaa ctataacaat ggcaacaatg atatttgcta catatataaa
    13561 accattatct ttagaattaa gtattatgat ttggagcata ggaattgtgg gtcatcttgt
    13621 gttaatagtc ttatttagta agaagttctt agttaaattc tcaataaaaa cggtatttcc
    13681 atcttggtat atagtatatg ttgggatagt tgcagctagt gttacggcac cagcatttaa
    13741 tcaacttttg attggcaaaa ttgctttttg gataggattt gtatcttata tagttcttat
    13801 accagtaatt ttaaagagag tatggataat caaggaaatg cctgaaccat ctttaccaag
    13861 tatagctata ttagctgcac cagggtcact attattgtct ggatatatta attctttttc
    13921 agataaaaat aatgtagtat tatacttgtt attcatatta tcaattgtat tttatattat
    13981 agttttggga tacttaccga aattattaag attgcctttt tatccgagtt ttgctgcatt
    14041 tacattccct atggcaataa gtgcaatggg tatgaaacta atgaatggtt atttaactaa
    14101 atcaggtcat tttataagtt ggatttcata tgcttctaag ttagaagaga taattgctac
    14161 agtgattatt ttatatgttt tagttttgtt tattatatat cttagtaaat ctgaaactac
    14221 atctaaagtt aaataagaat tattaaatat gtgtatttaa taggaatatt gatataaata
    14281 tatgaagata agataaacca tagaaactta atttagctta attttattgg aggaaaacaa
    14341 atgaaaacaa aagaagaata tttaaaagaa gttagaaaca tatcagaaga atactttaga
    14401 aaaggagagt ttttttgctc tgaagcagtt ctccagacaa taaatgatgc tttaggccaa
    14461 cctttaagtc cagagataac taagttagca tcaggatttc cgataggact tggaaaggca
    14521 caatgtcttt gcggagcaat atctggggga gagatggctt taggtatagt atatggaaga
    14581 gttcatggtg aagctatgaa tccaaagatg tttgagcatg ctaaaggttt gcatgattat
    14641 attaaaaaag agtatggtgc aacatgttgt agagctatta caaagaagtg ggatggtgat
    14701 aactttatgt ctcccgaaag aaaagagcac tgtattaaaa taacaggtca agttacagag
    14761 tgggttgcag ataagcttat agaagatgaa aaacttaata tcaaatagtg caatattagt
    14821 tggtgaattt ataaagttaa atttacttat agtataagat acttgatatt ctcgtattga
    14881 tagaaaaatt tatagcatat gtatttaatg aaatatactt atatttagag tgtggtttaa
    14941 tttcataaat acatatgcta ttattttaag tatataagca aatttattta aataaataga
    15001 aacagttaat ttatatgtac aaaactatat atgattagtg taaataaata cctattttat
    15061 aatactcaac ataaagacac cagacatgat tagtattata ccaataaaaa tagcaagcca
    15121 ttcttttttg ttcttctttt ctttaaaaaa tataatccct cctaaagtgg ctactatcac
    15181 acaactctga gagatagaaa aacttattgt aactcccaat gtattagtcg ttatgaacat
    15241 acctaaattt gctattgacc acaatatacc agtaattaaa ttgaataaaa cattttccat
    15301 atatacaatc tctttagaaa aatacttgac aataatagat gaagttatca acataccaac
    15361 agattgaggt aatataattc tatatccttc aattaaaaat atttgattag ttacaacata
    15421 taatgataaa aatagagatg ataataatac aactccaaca cattttaaca tatttttatc
    15481 tgtagatttt ttagtttgat aatttgtgag aagtatacca agtattatac ataatattga
    15541 taaagaacca atcagtaaca ttttagaact ggtccattca ttaaacaaga ttacagctaa
    15601 taatgtcgta aaagttaatt gtgaaccatt tgaaattggc attactttag atacactagc
    15661 aatttgaatt gctttaaact gcattaattg tcccagactc cagaatatgc cagaaatcat
    15721 acttatacaa aatgaaaaaa atgtaatttc aggatgtata accagagtta ttatagtgga
    15781 aaatataaac gcacttatgg atgtacctaa aagctgttca tgaggagaac ttttctttag
    15841 atttgcaact atgggcatca atccccatcc cattacagga agtaaagcaa taattattgt
    15901 cagcattaaa ctatttcctt tcatattaaa tttagacagc ttttaattta tcatctaaaa
    15961 ttaaagtgtt caatacataa aaattaccgt atttaatcag gaaatattag tagtttttta
    16021 gaaaaacatt ttccattaaa ataaagacaa agggaaggag taaaattgaa aatgttaact
    16081 gatatgattc aaaatcgtga aattaaaata ataaagtttt tattaaaaga aggtcataca
    16141 actgtaaaag caatagcaga tgatttagat gtttcagaaa aaacagtttc aaaatctctt
    16201 aaagaagtag aagcagtgct taaaaagata ggtctttctt taataagaaa acctaagata
    16261 ggtgtttata ttgatggaga tttaaaaaaa atacttcctt acctagataa taaaggaagt
    16321 caaattccta caaccagaga ggagagagtt atctatatat attcagtact tttaaagagt
    16381 aatgattata ttactataca acaactttct gatgaactat atataagtcg tggaactatt
    16441 gaaagggatt tagcagaagt tgaaaaactg ctaaaaaacg aagggatttc catatataag
    16501 aaacctagta agggaataaa gttaaatata agtgaaagag ataaaagaca acttactgct
    16561 aagtttatac ataaattttg gagtagaaac tggtatatta agcaagagca agaaagcttt
    16621 tatcaagcat ttgaaaagat acaagcagat gtaaatggta ttttttcgga agatgattta
    16681 tcaataatta ttgatattct taggaatttc agcagagaaa gaaaatttga gttctctgat
    16741 tatgaatttc agtcattagt tattcatttg gcaatagctg tagagagaat tagaaaaggc
    16801 gaatatatag aagaaagttt gtatactggt aatatagaaa ataatcaaat gtcaaatacc
    16861 aattatttag caaaacaatt agaagaaaaa ttttcaatat tattaccaaa atctgaaatt
    16921 ggatatataa atttacattt agtagcgtct gaccaacata gagatactaa tgaactaaaa
    16981 aatacttcaa ctaatccttg tgagacaagt acaaataata tatcaaatct tcgggaaatt
    17041 ataaaaaata cattgtatga gacagcttat gacaaggatt taattgatgg attaacttca
    17101 catgtacatt catcaataaa tagactgaaa tatggactta gtattaaaaa tccatatgta
    17161 aatacaatca aacaaaactt ttctttatca tttgagcaag ctttagattt aaagaaagta
    17221 attgaattta tatatgatat taggataaat gatgatgaat gtgcttatat agcattacat
    17281 tttgaagctt ttagagaaag aatgaaagaa cttccacaaa atattagagt aattctagta
    17341 tgcagtacag gattaggttc atctaggtta ttgtctgcaa gaataaaaaa atactttcca
    17401 atgataaaga ttgaaaaagt actttccgta caagaattag tatccagtaa aattgatgca
    17461 gatttagtaa taagtactat ttatttagag ttagaaacaa ttccaaccat agtagttagt
    17521 cctattttaa atgaaagtga tataagaacc ttggaaagaa atatacaaaa tgtttcaagt
    17581 tatacttcta agaagtataa atctttcaga aacttaatct ttgaagaaaa tatattgttg
    17641 aatattgaag cttcaaacta tgaagatgca attaagtata taacagataa cctaataaaa
    17701 aaaggttttg caaaagaagg tatagctaaa agtgcaattg agagagaaaa tttatcttac
    17761 acttctttcc aatcaatagc tacacctcat gctaatccta gttatattaa aaaatctaat
    17821 atatctgttg caacgttaaa aaatcctatt acatggggaa atgaaaaggt ggaagttatt
    17881 ttctttattt cattagaaaa tgacaaaaac ctagagcttg atgaaatata tgaagttttt
    17941 tatgacttca ttgacaataa aaaaaatata aatgacatat taagtgcaac ttccacaaag
    18001 gaagtgtacg atttgctagt ggaggagagt atatagtgaa aatatcagat gtattgaaaa
    18061 aagagcaaat tgtttttaat cttgatacaa atacaaagga agaaacaata aaaaaattaa
    18121 gtagtatatt tgttgaaaat gggattgtgg acaatgaaga agaatatgtt aagtctgttt
    18181 tggaaagaga agaacattca actacaggta ttggtaatgg tattgctatt cctcatggaa
    18241 aaagtaatgc tgtcaaaaaa tcttctataa tatttgcaaa gactaagcat aagattgaat
    18301 gggatgcttt agatgaaaaa ccagtagata gtattttctt attggctata agcaatattg
    18361 ataaggatag caatcatctt gtactattat ctaaattagc aactaaactt atggatgatg
    18421 acaatgtaga tgcactaaaa ttagccaatt cagaacaaga aataatcaat atatttagtg
    18481 aagaaggaga gatgtagaaa tgaaaagaaa aattatagca gttacagcat gtgcaacagg
    18541 agttgcacat acatatatgg cagctcaagc gttaaagaaa gcttcaaaaa agatgggtca
    18601 ccttataaaa gttgaaacac aaggagctac aggaatcgat aatgagttaa ctacaaagga
    18661 tgcacaaatt gcagaagtag taatatttgc agtagatact aaagtcagaa atgctgaacg
    18721 ttttgaggga aaagaaatac tagaagtacc agttaatgca cctataaagg atgcagagaa
    18781 agtaataaat gatgcactaa agttaattga cactaaataa atggagggaa atataatgtt
    18841 gaaaaagata gtctctgagt taaaaaagca tgtcttaact ggaatctcat atatgattcc
    18901 attagtaatt gcaggtgcta tgataatggc gatatctcgt gtaggtggtt ctttctataa
    18961 tataccagat atatgggatg ctaaatatgc agaaagtgct agtagtattg ttagattatt
    19021 acatgattta gatgggtttg gaggtactgc attaggatta atgtttcctg taattgctgc
    19081 atttatagga ttttctatag ctgataaatt agctattgta ccaggtcttg ttggaggtat
    19141 gattgctaaa gatataggtg caggattttt aggagctttg gcagttggtc ttatagcagg
    19201 atatacatgt ttgtttatta aaaatcatgt caaattacca aaatcagcag cttctatagt
    19261 accaatattt atagtaccag tatttgggac attaatcact gttgtattaa tcaattatgt
    19321 gataggtata ccttttgcca cattaaatac tggattagaa aattggttaa atggattatc
    19381 tggtacaaat cagatattaa tggcagctat tataggggct atgatggcag ttgacttagg
    19441 tggaccagtt aataaagcag ctttaacaac atcacttgca ttattaacaa gtggaattta
    19501 tgcgcctaac actgctgcaa tggtaggaat agttatacca ccactaggat tgggacttgc
    19561 tactatacta gcaaaacaaa aatataataa acagttacgt gaagctggga aatcatctct
    19621 tataatgggt ttaattggag taagtgaagg agcaattcct tttgcagtag aatctccatt
    19681 aaaagtaata ccttcatgtg taattggaac agcaattgct tcagctatgg cagttggttt
    19741 aggttcagta aatgcaactc caattagtgg attttatgga tggtttacag tagagaattg
    19801 gccaatgtat gtgttatcaa tagcagttgg aacagtaatt gtagctggat tagttatagt
    19861 attgcgtgga aatccagtga ttgaggatga tgaatttgaa gatgatgatt ttgatgaagc
    19921 agagtgggaa tcttaaaatt taataactat ttaagacgtg ttataagcta tattcaatat
    19981 gaatcttata ctaaataaag tgttaaatat tcagtttaga cttaaatata aaagataaag
    20041 aacagaggag aataaatgat aaaagcacat attgttaatc atacacactg ggatagagaa
    20101 tggtatttta cttctggaga tgcattagta cttagtgaac aactatttac agatgtaatt
    20161 gatgaattag aacgtaatcc agatgtaagt tttgtacttg atggacaact ttctattttg
    20221 gatgattatg tacaattaca caaagaaaaa atagaaatca ttaaaaagtt aataaaagaa
    20281 gatagactac atattggacc atggtttact caaactgatg cattctttgc tagaggagag
    20341 tctattttaa gaaacttaat gattggaatt tttgaaagta aaaagtatgg taagtatatg
    20401 aaaattgggt atttgccaga tacatttgga tttaatgcac agatgcctat actattaaag
    20461 catgtaggtc ttgataatat attcttttgg agaggtatac atcttggtaa acaggttcaa
    20521 tcaccatatt ttaagtggaa aagcttaaat ggagaaagtt atatatatgc agtaaatatg
    20581 ccacatggat atggaactgg tatgctttta gagccttcat taaagtatgt taatggacgc
    20641 ttagacccag ctattgattt tattaaatca tatactgatg tagatgaggt gttaatacct
    20701 tctgggaatg accagttaaa tataataggt gatttcaaaa ataaaattaa agcgattaat
    20761 gatatcggaa agtattcata tataacgagt tcatatcaag agtttttaaa atatataaag
    20821 tccatagaat cactagaaag ctatagaggt gaatttagag aacctgtatt agcaagaata
    20881 cataaatcaa ttggttctag tagaatggat ataaaattag catgtgataa actagaaaac
    20941 aagctgatta aaagaataga gccattatta gtaattgcta aaaagagtaa aattgaaata
    21001 agcaatcagt tacttataaa tacatggaaa aaacttttgg aaggacaagc acacgatagt
    21061 ttagctggat gtgtaactga tactgtaaca gatgatattc ttcaccgtat aagagaagca
    21121 aatgaaatat gtgacagtat tgaaaatact attgtaaaaa agatttcaga agggcttaaa
    21181 ttatctaaaa atgatatttt agtatttaat acagaagcta agcgttttaa tggatataaa
    21241 gagatacaag ttgtaagtga tagtaaaaat atttatttta aagataattt agatgctact
    21301 ataattgaag aaacttatgt aaaaccgaga gaaaatgtat tagaagaaac acctgctggt
    21361 aatatattta ttgaagaacc aggatattat atattaaaag taagaataaa tatacagctt
    21421 cctgcacttg gttataaagt tgttagtttt gaattaagtg ataaagaaat ggtgtcactt
    21481 gataaatcta atgacacttt tatatctaat gataattata agataatata tgaagatgga
    21541 agcttaaatt tacaacttaa agatggaact tacatatcaa actttttaac attaaaagat
    21601 agtggtaatg caggtgatac ctatgacttt tctccactaa aaaatgatga ggatataaaa
    21661 ctttcgtttg ataaagtgta tacagaaaaa gctttaggat atgaaaaaat ggtggttaaa
    21721 ggtactactt tactaccact tacattagaa gatagaaaaa acaaatatct taaagggaaa
    21781 ttaaatgtaa aagtaagtat tgtcttatct aaagaaaacc cattgatgga tgtaaaactt
    21841 tgtgttgata acacgatata taatcataga ctacgtgttc atataaaaac tgatataaaa
    21901 gataataaaa acatagcatc attgccattt ggatatataa caagaaaaaa tggagtttta
    21961 gacaactggg aagatattta cagtgaaatg cctatagatt tagaaccttt ggaaagtaat
    22021 attacgctta caaaccaaaa tagaagttgt actgtattta ctagaggaat aaaagagtat
    22081 caacatattg aagatgaaat tgcattgacc ttacttgcta ctacagatga actaggaaag
    22141 cctgatttat tatatagacc aggacgtgct tctggtgata caactaaaaa aggtcatata
    22201 agaattaaaa cagataaagc ccaaatgctt aaggaattag aattttcatt tgcaatatat
    22261 atggattcta aatcatttga tgaattggaa attgcgaatt taacccacaa ttatctaagg
    22321 gaatgtgtaa attatcaatt acaggattac aatttctttt tatatcgtat agataataag
    22381 attcaaaaat caattgtcaa taaaactgta agtagagaat tagaaataat atctttacca
    22441 gaaaactatc ttatatcagc atgttatcct tcttattaca gtaaagataa atttataata
    22501 agagtggaaa atccaagtag taatagaatg atattggatg agcaaatatt taaaaataga
    22561 aatgggaaaa ttgtaaatgc aatagaagat gtagaagaag aacaggtata tgaaatagca
    22621 ccttttgacg ttatttcaat attattggat ttataagtgt aaaagtaagt ttattgttta
    22681 aagtctgaca gatattaatc tgccagactt tttaatttgt ataaatttgg gtaaatatta
    22741 atgaatggtt ttagtattta aatatgaatt tagtatttaa tatagaattt attgaagtag
    22801 aataattagt ttaacaggat aagcagttta aataaagaat ta
//
LOCUS       DAMKNB010000059        22396 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.061, whole genome shotgun sequence.
ACCESSION   DAMKNB010000059 DAMKNB010000000
VERSION     DAMKNB010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 22396)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22396)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22396
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.061"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            complement(67..1098)
                     /locus_tag="PC494_002513"
     CDS             complement(67..1098)
                     /locus_tag="PC494_002513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative sulfate exporter family transporter"
                     /protein_id="HDF3913004.1"
                     /translation="MLKKKSSLTLKTIREILPGLFVSVLVGYISIFISILIPKVGAAS
                     ISIFLGMFVGNLFLNQKVFQKGYKFSETDLLSYSIVLLGATLSVSTLIDLKVSGILFI
                     ILQMTITIIAALYIGKKLGFEENFRFLMASGNAVCGSSAIGATVPVVNATDKEKGIAV
                     TIVNVTGIFLMFLLPIISQFLYSHELVKTSAMIGGTLQSIGQVVASGAIVGENVKDLA
                     TIFKIVRVIFLVVVVLVFGHMKNQSNREILEEEKDEIKKKKVTIPWYVIGFFITCALF
                     SMNIIPQEVSVLCKEISNKLEIIALAAIGLKVNVKDLVKQGKEVSLYGLFVGTVQVVS
                     AVVLIKIFI"
     gene            1286..2176
                     /locus_tag="PC494_002514"
     CDS             1286..2176
                     /locus_tag="PC494_002514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDF3913005.1"
                     /translation="MFEELKTFVAVVEYKNFTKAGEYLNLSQPSVSKHIKNLENYFKV
                     VLINRSIKQKTIFITESGQILYKRAKEILNLLNITYHDVSQVSDAITGHLKIGASLTI
                     GEYILPNFLALFSKKYPDIDVEVFIKNTSIVSSHVKDYILDIGLIEGTCSSPSFIQEY
                     FFEDKMVLALPYKSHLLKDFSFDKLQNQKWIVREDGSGTRDYLDMFLSVKEIIPKSMM
                     VFGSNYAVKESVRNNLGITIVSNLVTSLPVLNNELSVIELGSSYNRHFSYIFPKDITL
                     SKAATIFIEELKIFSNLNSI"
     gene            complement(2228..3154)
                     /locus_tag="PC494_002515"
     CDS             complement(2228..3154)
                     /locus_tag="PC494_002515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketopantoate reductase family protein"
                     /protein_id="HDF3913006.1"
                     /translation="MKNQLNENHKKVVFFGVGAVGATFAEQFFNSKYDFKILCDNERK
                     KRYLEEGFIINGKRYDFDYVTKDEYKQEADFIIIGLKYNNLKENIKELDGLVGKNTVI
                     MSLLNGVDSEEIIGERFGIEKMVYSYVTNIDAKKINNNIIHTTNGIIVFGNKDNSEDR
                     KTNIITEVFDDVNIEYTLSKDIQRDMWWKYMVNIGVNQTSAILGAPYGVFQSSEHLRE
                     LAKSAMREVVAIAQAKNISLTEDDVEHSLHRILEHSKEGRTSMLQDVEAHRLTEVDMF
                     SKNICKLGKKYNIPTPINQTFFYMIKVIESRF"
     gene            complement(3497..4687)
                     /locus_tag="PC494_002516"
     CDS             complement(3497..4687)
                     /locus_tag="PC494_002516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009271880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HDF3913007.1"
                     /translation="MSNVKRKDSKNRNLRNGESQRKDGRYVYKYTDIYGKPQFIYSWK
                     LVPTDKTPAGKRDDISLREKEAQIKKDLNDGIDTVGGKMTVCQLYDKKNSQRKNIKRA
                     TEKGRQYLMNALKNDPLGMRAIDTVKQSDAKEWAIRMSEKGYAYKTIDNYKRSLKASF
                     YMAIQDDCIRKNPFEFKLSDVLEDDTEQKVILTPEQEERLLAFMEKDKIYSKYYDEVV
                     LLLETGLRISEFCGLTTHIDMQNRILNIDHQLLKDSEMGYYIETPKTKNGKRELPLTE
                     RAYQAIQRILKNRGKAQPLIVGGYSNFLFLNREGLPKVAGNYEGMVRGLIKKYNKYHT
                     DKLPNITPHSFRHTYCTNMANRGMNPNTLQYLMGHANITMTLGYYAHGTFQSAKAELE
                     RLAC"
     gene            complement(4766..4969)
                     /locus_tag="PC494_002517"
     CDS             complement(4766..4969)
                     /locus_tag="PC494_002517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HDF3913008.1"
                     /translation="MNNTDVPIWEKYTLTVEEASKYFRIGEKKLRKLAEENLDAGWVI
                     VNGNRIQIKRKQFEKIIDTLDEI"
     gene            complement(5343..5597)
                     /locus_tag="PC494_002518"
     CDS             complement(5343..5597)
                     /locus_tag="PC494_002518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009264382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF3913009.1"
                     /translation="MKQLFKKPSYYLISSAMDGNEKAIEKLLAFYDPYISKCCLRSLY
                     DEYGNVYIVVDMELKGRIREALIKMILGFDIEDMDLEPEE"
     gene            complement(5601..6020)
                     /locus_tag="PC494_002519"
     CDS             complement(5601..6020)
                     /locus_tag="PC494_002519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009269712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HDF3913010.1"
                     /translation="MKPSDFQKTVQCRFESCLKKVVRSVVKDYYKELNRRKNKEISFS
                     ELPDVIVDKMTVWDDYETDYTIFSVCGIDIRVLDDELAEALKKLPERKRNTLLMYYFL
                     EMTESEIANLQKITQSGVFRNRHHALEIMKKILKEEH"
     gene            complement(6312..6686)
                     /locus_tag="PC494_002520"
     CDS             complement(6312..6686)
                     /locus_tag="PC494_002520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDF3913011.1"
                     /translation="MELYLNDVYPYAQQISNYIEREIFQQKLKAGQKLLSITNLSKEL
                     NVSKHTIQLSYKILRKKELIVKKGNDFFVTKDNCCIITKMKEETDLQIIKCLHELAEM
                     GYSREQTKSLILRKLETLKFPQ"
     gene            complement(6734..7735)
                     /locus_tag="PC494_002521"
     CDS             complement(6734..7735)
                     /locus_tag="PC494_002521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HDF3913012.1"
                     /translation="MSFFTFLEEKITEILFQLFFLALVAFLLIFYGVDTLFVVLLVIL
                     FISIQGLFQWCLYRKKRKASQHIIDLVDGLEETYYIADVLPKPKEFQNEAYYYALKKA
                     CKSMNDEIGKITEEKQDYQEYVESFAHEIKIPIGALSLTFDNTKNYTLKKETDKIFQL
                     VEQMLYYARSENTEKDYFVKQLQLDEVIHNVILKFRHSLMERKVIINIHDIENVVYTD
                     EKWLTFILSQIVQNAIKYFDKQENKLTIYSQDNGTNILLVIEDNGCGIKTSDLSRVFE
                     KGFTGSNRNKANATGMGLYLSKKLSDRLGLKLDITSKETEYTRLTITFPKGTVHNLH"
     gene            complement(7732..8391)
                     /locus_tag="PC494_002522"
     CDS             complement(7732..8391)
                     /locus_tag="PC494_002522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009269714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding response regulator"
                     /protein_id="HDF3913013.1"
                     /translation="MRIAIIEDDEITRLELSKLLNTQGYETVLLTNFENLTEELKQYC
                     VELVLLDINLPYENGYEVCRKIKQAMPVPIIFVTSRDTNADELKSIQVGGIDFITKPY
                     DTLILLEKIKRALQLSNPNNFRELVKKDCTLDLHLSILKYQEKSIELTRNEFRILYYF
                     FMNEDKVISKEELLEKLWNDKYYLDENVLLVNMTRLKKKMKEIGIVHLLENIRGKGWK
                     L"
     gene            complement(8450..10429)
                     /locus_tag="PC494_002523"
     CDS             complement(8450..10429)
                     /locus_tag="PC494_002523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009269715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF3913014.1"
                     /translation="MLGKLAVRNTKRSIKDYLIYLITVTIAFSLIFAFNLVASSEEVI
                     ELSTGMDTFKYILAFVNVVIIFVICFLINYTTKFMFEKRSKELGTYMLLGIRKKEIAR
                     LLVIENVLLAICALVLAIPLGFIFSQFVSLVIVNLLGIPEVIFISINFVSIGLLAIYF
                     LAIYVLVLLNLLRRIRKMTVHDFLYFDKQNEKKMFRSNKKRNIIFIVSVILGITAILL
                     WASRWTMENSGKQETLTYLMISMMMLIISIYGVSATCADMLLSVLLKNKKLKYQKDNL
                     FVTRTFASKARTMSFTFGTLSMLILLSLLCLNFSSINKGVYKASIEMTAPFDVHVFEE
                     KQPFKDFKEYVNVVDEDYTINKAIEFDVYKEPKHQMQNYFDVQFYDYDPVMKLSDYNE
                     ILKLKNMDTIELSNDEYFLVTSKDLLYKVENNKDIEKIQLTSGKELKLKGIDTKTYWY
                     QINNTGRFAVIVPDEYVQGLEVSEQHLIIDTIEETDTKLREKIKQDLKHRLVIVNDDG
                     ETVVQYYRLSVRGSAIEEQNTMTAMIASICLYIAFILISAVGTVLAIQSLSDSTKYKY
                     RYQTLKRLGVNDKSLFKTIRKQLLILFGVPVIYSILASFFMLVSVNNVYKIYLESEYS
                     YLIYFVVGLAIFFFIYGIYWIATYIGFKRNINEES"
     gene            complement(10419..11189)
                     /locus_tag="PC494_002524"
     CDS             complement(10419..11189)
                     /locus_tag="PC494_002524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF3913015.1"
                     /translation="MEHILNLEQVKKYYGGNSGNITKAVDGISMYVDKGEFVAIMGAS
                     GSGKTTLLNCISTIDTVTSGHITVNNQDITKIKDKDFADFRRENLGFIFQDFNLLDTL
                     TIEENISLSLVINKQNPADIDKRVHAIADKLGIRDILSKFPYEVSGGQKQRCACARAL
                     INEPKLILADEPTGALDSKSSRLLLETMSDINKKMQATILMVTHDPFSASFCKRILFL
                     KDGKIFNEIFRGEKSRKDFFNEILDILTLLGGEVGNVR"
     gene            complement(11389..11907)
                     /locus_tag="PC494_002525"
     CDS             complement(11389..11907)
                     /locus_tag="PC494_002525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018595824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HDF3913016.1"
                     /translation="MNVLDIAKKRYSVRTYEDKPVEKEKLDKILASAHVAPTAANLQP
                     VKLLVVQDKERLKSIAKAGNIYNAPLAIIVCADHSKAWKRPFDNKQTTDIDATILTDH
                     MMLQATELGLGTVWVCFFKPNVIKREFQLPDNLEPVNILVIGYGKETPADPERHFATR
                     IPMEELVSYDYL"
     gene            12033..12356
                     /locus_tag="PC494_002526"
     CDS             12033..12356
                     /locus_tag="PC494_002526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007488174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HDF3913017.1"
                     /translation="MENNCCGFSCPVEATIQLIGGKYKAVILWHLMNKTLRYSEIHKL
                     IPKATDKMLAQQLRELEKDGLINRKVYPVVPPKTEYSLTEFGKTLTPILDELCNWGEN
                     YLLQN"
     gene            complement(12414..12644)
                     /locus_tag="PC494_002527"
     CDS             complement(12414..12644)
                     /locus_tag="PC494_002527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004612099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3913018.1"
                     /translation="MIGLKKRDIKKALKAGANASGVSLADIRADIEATIDEAMNSTDP
                     EVQANFKKYFGNKRPTPEEYIYKITKKTKVKL"
     gene            complement(12747..13649)
                     /locus_tag="PC494_002528"
     CDS             complement(12747..13649)
                     /locus_tag="PC494_002528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HDF3913019.1"
                     /translation="MFKKNKKQTENVKEKMVRTVKVGTHKKTVIALWVVLIASVSFGV
                     YKNFTAIDQHTTHEKEIIELRLQDTNGIENFVKNFAKSYYTWSNSKEVIEARTQAISG
                     YLTKELQDLNVDTIRMDIPTSSTVTDVIVWSIEQSGTDTFSATYEVDQQIKDGEQTSN
                     VKATYTVKVHVDADGDMVIVQNPTLAPAIEKSDYEPKTPETDASVDADTVNDAAAFLE
                     TFFKLYPTATEKELAYYVSGNVLEPIGRDYLYSELVNPIFTKDGGNVKVKVSVKFLDN
                     QTKATQVSQYELVLHKDSNWKIVG"
     gene            complement(13665..14672)
                     /locus_tag="PC494_002529"
     CDS             complement(13665..14672)
                     /locus_tag="PC494_002529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009243519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysozyme/C40 family peptidase"
                     /protein_id="HDF3913020.1"
                     /translation="MKLKHIALIGSLFPLLFSLVLFFGVLISADSDDENSNFSSGITG
                     MNLSAEVLKHQPMVEKYAKEYGISEYVNVLLAIIQVESGGTAEDVMQSSESLGLPPNS
                     LDTESSIKQGCKYFASLLSSCKNQGIDDLNVAIQSYNYGGGYVGYVAGKGKKHTYNLA
                     EIFAREKSGGKKVTYTNPIAVAKNGGWRYGYGNMFYVELVNQYLTVPQVSGELAQKVM
                     NEALKYQGWKYVYGGSNPNTSFDCSGLVQWCYGKAGISLPRTAQAQYDATQHLPLSQA
                     KAGDLVFFHSTYNAGTYVTHVAIYVGNNQIYHAGDPIGYADLSSSYWQQHLIGAGRVK
                     Q"
     gene            complement(14669..16867)
                     /locus_tag="PC494_002530"
     CDS             complement(14669..16867)
                     /locus_tag="PC494_002530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDF3913021.1"
                     /translation="MKERIKGAFTKKKILHVLKMALFVVALSLILLSLLGTVAHATGL
                     VDDTINAENLYSKYPLSNYQLDFYVDNSWSWLPWNWLDGIGKSVQYGLYCITNFVWTI
                     SLYLSNATGYVVQEAYKLDFINDMADSIGKSIQTLAGVTQNGFSSTGFYVGFLLLIIL
                     VVGLYVAYTGLIKRETSKALHAVINFVVVFVLSASFIAYAPDYIKKINEFSSDISTAS
                     LDLGTKIMLPNSDSEGKDSVDLIRDSLFSIQVEQPWLLLQFGNSNAEEIGTDRVEALV
                     SASPEDEDGKTREEVVKTEIEDNDNNNLTIPQVVNRLGMVFFLLFFNLGITIFVFLLT
                     GMMLFSQILFIIFAMFLPISFLLSMIPSYESMAKQAIVRVFNTIMTRAGITLIVTVAF
                     SISSMFYNISTDYPFFMVAFLQIVCFAGIYMKLGDLMSMFSLNAGDSQNMGRRIFRRP
                     YLFMRHRARRMERRLAGAVTAGGVAGAVAGSTISNRKPTRNTATKDSRGNTSTSSMGQ
                     RAGSKVGAVLDTKNKVKDKANAVKENIKDMPTQTAYAVYSAKEKAKSSVSDFKRGMVQ
                     EQLSRQTGRLERQEQHRQNIADKRMELQKAQEARQAQRKADGSATTGATRPHERPATA
                     STIPKPSAEKMQEVKRPATATTSKASEPVKTTVIKERPLSSGASDRKATQSAQIAHRQ
                     NVEKVVSQETRQNYTKDRRTKVQQTQSVQKNQQTTEKTRNLVTKKGQKKK"
     gene            complement(16867..19317)
                     /locus_tag="PC494_002531"
     CDS             complement(16867..19317)
                     /locus_tag="PC494_002531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HDF3913022.1"
                     /translation="MFPIKYINNNLVWNKDNEVFAYYELIPYNYSFLSAEQKFIVHDS
                     FRQLIAQSREGKIHALQIATESSIRSMQEQSKKLVTGKLKEVAYQKIDEQTEALVSMI
                     GDNQVDYRFFLGFKLMVTEEQLNLKNIKKSAWLTFTEFLHEVNHTLMNDFVSMPNDEI
                     NRYMKMEKLLENKISRRFKVRRLEINDFGYLMEHLYGRDGIAYEDYEYQLPKKKLNKE
                     TLIKYYDLIRPTRCVIEESQRYLRLEHEDKESYVSYFTVNAIVGELDFPSSEIFYFQQ
                     QQFTFPVDTSMNVEIVENRKALTTVRNKKKELKDLDNHAYQAGSETSSNVVDALDSVD
                     ELETDLDQSKESMYKLSYVIRVSAPDLDELKRRCDEVKDFYDDLNVKLVRPAGDMLGL
                     HSEFLPASKRYINDYVQYVKSDFLAGLGFGATQQLGETTGIYMGYSVDTGRNVYLQPS
                     LASQGVKGTVTNALASAFVGSLGGGKSFCNNLLVYYSVLFGGQALLLDPKSERGNWKE
                     TLPEIAHEINIVNLTSDKDNAGLLDPFVIMKNVKDAESLAIDILTFLTGISSRDGEKF
                     PVLRKAVRSVTQSDKRGLLHVIDELRREDTPVSRNIADHIDSFTDYDFAHLLFSDGTV
                     ENAISLDNQLNIIQVADLVLPDKDTTFEEYTTIELLSVSMLIVISTFALDFIHSDRSI
                     FKIVDLDEAWAFLNVAQGETLSNKLVRAGRAMQAGVYFVTQSSGDVSKESLKNNIGLK
                     FAFRSTDINEIKQTLEFFGIDKDDENNQKRLRDLENGQCLLQDLYGRVGVVQIHPVFE
                     ELLHAFDTRPPVQRNEVE"
     gene            complement(19295..19693)
                     /locus_tag="PC494_002532"
     CDS             complement(19295..19693)
                     /locus_tag="PC494_002532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009274602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HDF3913023.1"
                     /translation="MKKIKSYTGIWNVEKVLYAINDFNLPFPVTFTQITWFVITEFII
                     ILFGDIPPLSMIEGAFLKYFGIPVALTWFMSQKTFDGKKPYSFLKSQITYALRPKITY
                     AGKAVKLHKQILNETITAVRSVNYVPDKIY"
     gene            complement(19803..20306)
                     /locus_tag="PC494_002533"
     CDS             complement(19803..20306)
                     /locus_tag="PC494_002533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004843360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HDF3913024.1"
                     /translation="MIDDMAVYIANLGKYNEGYLVGAWFTFPIDEEDVKEKIGLNEQY
                     EEYAIHDTDNFPIAIGEYVSIEELNEMYEMIEELPDYIVECLDEFISHYGTLEEVVEH
                     KDDIYYYPDCETMTDVAYYYIDELQALGDIPPSLQNYIDYEAYGRDLDMGGYFIETSR
                     GMCEIPY"
     gene            complement(20324..20827)
                     /locus_tag="PC494_002534"
     CDS             complement(20324..20827)
                     /locus_tag="PC494_002534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004843359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HDF3913025.1"
                     /translation="MQETRVLVETKGTTGEETTSYWFDLPIDVAEFEEKLGVGAESQD
                     YCIIEKVLPFADEIHEHTSVYQLNELDFMYRQLSSDMQEEYTALLTVCENLEALYICR
                     NVITVYPDCKSMIDVARQKLMNDPTFKHLSEDCQEYYFDFEAYASHLQEHGKFLVTEH
                     GIFELPE"
     gene            complement(20746..21042)
                     /locus_tag="PC494_002535"
     CDS             complement(20746..21042)
                     /locus_tag="PC494_002535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005339688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HDF3913026.1"
                     /translation="MNDIFKDMQAKVGCDYLSDLPSYKRKVWHEMKRLNPADHEERQL
                     EDFSKYVFGMSYQTLKDVMKQQKGREEQCRKQGCWWKRKEQLAKKQHHTGSTCR"
     gene            complement(21134..21553)
                     /locus_tag="PC494_002536"
     CDS             complement(21134..21553)
                     /locus_tag="PC494_002536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002578899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="HDF3913027.1"
                     /translation="MNEREKIIRLWFDMWLKQQDLGMDKIFTEDVVYTESWCPKYKNL
                     KTVKHWFNEWNTRGKVIIWDIKQFFHKENQTVVEWYFKNEMNTGSVEEFDGISLIEWT
                     EDNKIKSLKEYGCNLNNYNPYQHSDSPQFRDEKISWF"
     gene            complement(21614..22120)
                     /locus_tag="PC494_002537"
     CDS             complement(21614..22120)
                     /locus_tag="PC494_002537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDF3913028.1"
                     /translation="MIIYSKLEINRIKDFWELLNRLDTETDYMMYEPNERKAKTTIQE
                     LKLDIQDNVIQGFDFLQVATENDKIVGYIRAERGKFERNFHTAYIVIGILKKYRGKGI
                     GTTFFNNLDLWAKTNNIVRLELTVECCNNTAKNLYEKNGFKIEGIRKKSMFVAGSFVD
                     EFYMAKIL"
     gene            complement(22199..22360)
                     /locus_tag="PC494_002538"
     CDS             complement(22199..22360)
                     /locus_tag="PC494_002538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3913029.1"
                     /translation="MAIVVIGIYLGFKREFSKLIGFLVVALIAVGLVFNAGGVKDVLL
                     ELFNKIIGA"
BASE COUNT         6540 a         4595 c         3571 g         7690 t
ORIGIN      
        1 attataaatt attagtatca tattatttta attaatcaaa ttaatattac aaatactatt
       61 tttatgctat ataaatattt ttattaaaac tacagctgat acaacttgta ctgtacctac
      121 aaataaacca tataaagaaa cttctttccc ttgtttcact aaatctttta cattaacctt
      181 taatccaatt gctgctaaag ctattatttc tagtttgtta cttatttctt tgcacaacac
      241 agatacttct tgtggtataa tgttcattga aaaaagtgca caagttataa agaatccaat
      301 tacataccat ggtatagtca cttttttctt ttttatctca tccttttctt cttcaagaat
      361 ttccctatta gattgatttt tcatatgtcc aaatactaat acaacaacaa ctagaaatat
      421 tactcttact atcttaaaaa tagtagctaa atcttttaca ttttctccaa caattgctcc
      481 acttgctaca acctgaccaa ttgattgcaa agttccacct atcattgctg aagtttttac
      541 aagttcatgg ctatataaaa attgagatat tattggaagt aaaaacataa gaaatatacc
      601 agtaacattt acaatagtta ctgcaattcc cttttcttta tctgtcgcat taaccactgg
      661 aactgttgct cctattgcag aagaaccaca tactgcattt ccacttgcca ttagaaatct
      721 aaagttttct tcaaatccta gttttttacc tatataaagt gcagctatta ttgttattgt
      781 catttgcaat attataaata aaattcctga aacttttaag tctattaagg tagatacact
      841 gagtgttgct cctaatagta ctattgaata tgataacaaa tctgtctctg aaaatttata
      901 acctttttga aatacctttt gatttaaaaa taggtttcct acaaacatac ctaaaaatat
      961 agaaattgat gctgccccta ccttaggaat taaaatagaa ataaatatac taatataacc
     1021 tactaatact gatacaaaca gccctggtaa tatttccctt atagttttta atgtcaaact
     1081 gctttttttc tttaacataa tatacctacc ttataattaa tatagttttc ttcatagcaa
     1141 tagtatataa ttgtaataac cataagtaaa ataaatatat aatatcgtaa tgattaatgt
     1201 ttttaatggt tattatatat agtataatta tctgtagaaa gtatataaaa aatgtaaaat
     1261 ttcattaggt aaaggagaca aaaaattgtt tgaagaatta aaaacatttg tagctgttgt
     1321 tgaatacaaa aactttacta aagctgggga atatttaaat ctatcacaac caagtgtaag
     1381 taaacacata aaaaatctag aaaattattt taaagttgtt cttataaaca ggtccattaa
     1441 acaaaaaacc atttttataa cagaaagtgg acaaatcttg tacaaaagag ctaaagaaat
     1501 attaaatctt ttaaatatta cttatcatga tgtaagccaa gtttcagatg ctataactgg
     1561 tcacttaaag attggtgcaa gtttaactat tggagagtat attttaccaa attttctagc
     1621 attattttct aaaaagtatc ctgacataga tgtagaagtt tttataaaaa atacatcaat
     1681 cgtatcttct catgttaagg attatatttt agacattggt cttattgaag gcacttgctc
     1741 ttccccttca tttattcaag aatatttttt tgaagataag atggttttag cacttccata
     1801 caagagtcat ttattaaaag attttagttt tgataaactt caaaaccaaa aatggatagt
     1861 cagggaggat ggttctggaa ccagagatta tttagatatg tttttaagtg ttaaagaaat
     1921 tattccaaaa agtatgatgg tttttggaag taattatgct gtcaaagaat ctgttagaaa
     1981 taatttagga attacaatag tctctaatct agtgacaagc ttacctgttc taaacaatga
     2041 gctgtctgtc atagagcttg gaagcagcta caacagacat ttctcatata tatttccaaa
     2101 agatataact ttatcaaaag cagcaactat tttcattgaa gagttaaaaa tatttagtaa
     2161 cttaaatagt atataacatt aataaaattt aaaatcaata attatcaata tttcttacaa
     2221 agacccttta aaatctactt tcaattactt ttatcatata aaagaaagtc tgatttatag
     2281 gagtaggtat gttatatttt tttccaagtt tgcagatatt cttagaaaac atatctactt
     2341 ctgtaagtct atgagcttcc acatcttgaa gcattgatgt tcttccttct tttgaatgtt
     2401 ctagtattct atgtaatgaa tgttccacat catcttctgt aagagatatg ttttttgctt
     2461 gtgctatagc aacaacttcc ctcattgcag attttgctaa ttctcttaaa tgctcagaac
     2521 tctgaaaaac tccataaggt gcaccaagta tagctgaagt ttgatttaca ccaatattaa
     2581 ccatgtactt ccaccacata tctcgttgaa tatcttttga taaagtatat tctatattta
     2641 catcatcaaa gacttcggtt attatattag tttttctatc ttcactatta tctttgttac
     2701 caaatacaat tatcccatta gtagtgtgta taatattatt attgattttc tttgcatcta
     2761 tattggtaac atatgaatat accatttttt caattccaaa tctttctcct attatctctt
     2821 cgctatcaac tccatttagc agagacatta taactgtatt ttttccaact aatccatcta
     2881 attcttttat attttctttt aaattattat attttagacc tataattata aaatcagcct
     2941 cttgtttata ctcatcttta gttacataat caaaatcata cctttttcca tttattataa
     3001 atccttcttc taaatatctt ttctttcttt cattatcaca aagaatttta aaatcatatt
     3061 tagagttaaa aaattgttct gcaaaagtag ctcctacagc acctactcca aaaaatacaa
     3121 cctttttatg attttcattt aattgatttt tcatacttac ccctccctaa tatataatac
     3181 ttttacctta tacttatatt gtactgctac tatctcttat tttgtaaata tatttttaac
     3241 aaaaaaaaca gctaaccttc atttataagg ctaactgctt tttattttta agttatatgt
     3301 tatattacaa atttttaaaa taaaaactta ctaaatttct gattatcttt tcataagttg
     3361 gtaaatgccg atatatcccg tattttagag ctttatcggt attttctttt tggaagatac
     3421 cttgcataag ctggcattta ccagcatgaa aatgcaacca aaagtagtaa atgagtagta
     3481 aatataagct ccgatattaa caagccagtc tttccagctc tgcttttgca gattgaaatg
     3541 taccgtgtgc gtaatagcca agtgtcatgg ttatgttagc gtgtcccatg agatattgca
     3601 gggtgtttgg gttcattcct ctgtttgcca tattcgtaca ataagtatgt cggaatgaat
     3661 gtggtgtgat gttcggtaac ttgtctgtgt gatacttgtt atacttctta atcagtcctc
     3721 gcaccatgcc ctcatagttt cctgcaactt taggtaagcc ctcacggttc aagaatagga
     3781 aattgctgta accacctaca atcagcggtt gtgcttttcc tctgttcttt agtattcttt
     3841 ggattgcttg ataagcacgt tctgtcaatg gaagttcccg ttttccattt ttggtctttg
     3901 gcgtttcaat atagtagccc atttcgctat ctttcaataa ctggtggtct atattgagta
     3961 ttctattctg catatcaata tgcgtcgtca atccgcaaaa ttcagaaata cgaagtcccg
     4021 tttccagcag aagcacaacc tcatcataat acttgctgta aatcttgtcc ttttccataa
     4081 aggcaagcag gcgttcttcc tgctctggtg taaggataac tttctgctcc gtatcatctt
     4141 ccagaacatc acttagctta aattcaaacg ggttctttct gatacagtcg tcttgtatcg
     4201 ccatgtaaaa tgacgctttc aaggaacgct tgtagttatc aatcgtttta taggcatatc
     4261 ctttttcgct cattctgata gcccattctt tagcgtccga ctgcttaaca gtatcaatcg
     4321 ccctcatacc caacgggtca tttttcagag cgttcataag atactgtcgt cctttttcag
     4381 tagccctctt gatgttcttt ctttggctgt tcttcttgtc ataaagctgg cagactgtca
     4441 ttttaccacc gactgtgtcg ataccgtcgt taaggtcttt ttttatctgt gcttcttttt
     4501 ccctcaacga tatatcatca cgctttccag caggtgtctt gtctgtcggt acaagtttcc
     4561 aagaatagat aaattgtggc tttccgtata tatcggtata tttataaacg tatcttccgt
     4621 cttttcgctg gctctctcca ttacgcaaat tgcgattttt actgtctttt cgtttcacat
     4681 tagacatagt gtaaagctcc tttccgtcat ggaatgagcc gtgatacgct atatcttatt
     4741 ataccatatc tacggctcaa tgacattaga tttcgtccaa tgtatctatg attttttcaa
     4801 attgttttcg cttaatctga atacggttgc cgttcacgat aacccagcca gcgtcaagat
     4861 tttcttcggc taatttacgc aatttctttt cgccaatgcg gaagtatttg gacgcttctt
     4921 caaccgtcag cgtatatttt tcccaaatag gcacatcagt attgttcata atctatgcac
     4981 cccctttact gtgtgtcgtt ttttacaagc aggcagacgg ctttggaaag ctccattagt
     5041 atctcaacta ttcccattct tgtgggcaga accgcaccat gcggacgtat cattattctg
     5101 tgaggatagg tcgtggcaaa acaacttttc caacagtcgc tctcggatca ctgcgtgggt
     5161 cgctcgcttt cttttgaaaa ggtcgtggcg tacagtcccc gtggctcgcc atctcacaaa
     5221 cgtatctgtc tgctttattc agttgtcaaa gagctgtggc gaaagcgtgt tgctttcata
     5281 taaaagcagg tggcagagca ggaaagaggg gggatattaa atcatgctcc gctaaaaact
     5341 gcttattctt ctggttctaa gtccatatct tcaatatcaa aacctaaaat cattttgata
     5401 agtgcttctc tgatacgtcc ttttaattcc atgtctacaa caatataaac attgccatat
     5461 tcgtcataaa gtgaacgtaa acagcacttt gatatgtacg ggtcataaaa tgccagcaat
     5521 ttctcaatcg ctttttcgtt tccgtccata gctgatgaaa tcaagtaata ggacggcttt
     5581 ttaaataact gtttcatttt ctaatgttcc tccttgagta tttttttcat aatttccaaa
     5641 gcgtgatgtc gatttctaaa tacaccgctt tgcgtgattt tctgcaagtt ggcaatttca
     5701 ctttctgtca tttccaaaaa gtaatacatc aacagagtat tgcgttttct ttctggaagt
     5761 ttcttcaatg cttctgccaa ttcatcatca aggacacgaa tatcaatgcc acatactgaa
     5821 aagattgtat aatctgtttc gtagtcgtcc caaacagtca ttttatcaac aatgacatct
     5881 ggcaattcgc tgaaagatat ttctttattt ttacgacggt ttaattcctt gtaataatct
     5941 ttcacgacac tacgaacaac tttctttaaa caactttcaa aacgacattg aactgttttc
     6001 tggaagtcag acggtttcat caatctcacc tcctttcctt tatgatttga aaagtgttta
     6061 tccctctttc cgcaccatat aaggacagct aggtgtgatt taatgacctc ttttgaaaaa
     6121 tttttaagtt tttttcgggt atgaaaaaag cccgcacaaa acatatagtc tgtacgagct
     6181 tttaaagcta aataatattt attttttaat agtgtactgt taggtggaat taaattgtaa
     6241 agaattgcac ttaaaacatt ccataactca agccccctta cagcaaaata ctatgcaatg
     6301 cctaatcgaa cttattgagg aaattttaaa gtttctaatt ttcttaaaat caaggatttt
     6361 gtttgttctc ttgaatatcc catttctgct aattcatgca gacatttgat tatctgtaaa
     6421 tctgtttctt ctttcatttt tgttattata cagcagttat cttttgtaac aaaaaaatca
     6481 tttccttttt ttacgattaa ctctttcttt ctcagtattt tataagataa ttgaattgta
     6541 tgtttactaa catttaattc tttacttaaa tttgttattg aaagtagctt ttgacctgct
     6601 tttaatttct gttgaaaaat ttctcgttct atataatttg atatttgttg tgcataaggg
     6661 taaacatcat taagatataa ctccatgtgt atcacttcct ttgttttatc atcaataagc
     6721 aactattcaa tgcttaatgt aaattatgga ctgttccttt tgggaatgta attgtcagtc
     6781 ttgtatattc cgtttcttta gaagtaatat ccaatttcaa acctagtcta tcagataatt
     6841 ttttcgataa atacagtccc atgcccgttg catttgcctt gtttctgtta gaaccagtaa
     6901 agcctttttc aaatacacgg gataaatcag acgtttttat tccacagcca ttatcttcta
     6961 tcacaagcag tatatttgtt ccgttgtctt gactgtatat cgtcagtttg ttttcctgct
     7021 tgtcaaaata cttaatcgca ttttgcacga tttgagatag aatgaatgtc agccattttt
     7081 catcagtata tacaacattc tctatgtcat ggatattgat aattactttc ctttccataa
     7141 gtgaatgacg aaatttcaga atgacattat gtatcacttc gtctaactgc aactgtttta
     7201 caaaatagtc cttttccgta ttttcactcc ttgcatagta gagcatttgt tccaccaact
     7261 gaaatatctt gtctgtttct ttttttaacg tgtaattttt cgtattatcg aacgtcaaag
     7321 acaatgctcc tatcggtatt ttaatttcat gggcgaaact ttccacatat tcttgataat
     7381 cctgcttttc ctctgtgatt ttaccgattt catcattcat agatttgcag gcttttttta
     7441 gtgcgtagta ataggcttca ttttgaaatt cttttggctt tggtaaaaca tctgcaatat
     7501 agtaggtttc ttccaatccg tctactaaat caataatatg ttgcgaagcc ttacgtttct
     7561 tccgatacaa acaccattga aaaagccctt gtatgctgat gaacagaatt accagcaata
     7621 caacaaatag cgtatctaca ccgtagaaaa tcaagagaaa tgctactaag gcaagaaaga
     7681 aaagctgaaa caatatctct gttatttttt cttctaagaa tgtaaaaaag ctcacagttt
     7741 ccaacccttt cctcgtatat tttccaataa atgaacaata ccgatttctt tcattttctt
     7801 ttttagacgg gtcatattaa ccagtaatac attttcgtct aaataatatt tgtcgttcca
     7861 cagcttttcc aatagttctt ccttactgat aactttatct tcgttcataa agaagtagta
     7921 taaaatacga aattcatttc ttgtcaattc aatgcttttc tcttgatact tcaaaataga
     7981 taaatgtaaa tcaagggtac aatctttttt aacaagctca cggaaattat tcgggtttga
     8041 taactgcaat gcacgcttga tcttctcaag aagaataagc gtgtcatacg gctttgtgat
     8101 aaagtcaatt ccacccactt gaatactttt caattcgtca gcatttgtat ctctgcttgt
     8161 tacaaagata ataggtactg gcatagcttg ttttattttc ctgcatactt catagccatt
     8221 ttcatacggc aggttaatat caagcaaaac cagctctacg caatattgct ttaattcctc
     8281 tgtcagattt tcaaagttag tcaacaagac tgtttcatat ccttgtgtgt tcaatagttt
     8341 agaaagctcc agacgagtga tttcatcatc ttcgataatt gctattctca tttccacacc
     8401 cccttgattt accaatataa taattccaca gcaggagagc aagaaaaatc taactctcct
     8461 cattgatatt tcgtttgaaa ccgatatacg ttgctatcca ataaattcca tagataaaga
     8521 agaaaatcgc caaacctact acgaagtaaa ttaaataact atactcactt tctaaataaa
     8581 ttttataaac attattgact gataccagca taaagaaact tgcaagaatt gaataaataa
     8641 ctggaacacc aaataatatt agtaattgct ttctgattgt tttaaataat gatttatcat
     8701 tcactcccaa tctttttaat gtttgatagc gatatttgta ctttgtagag tcacttagtg
     8761 attgaatagc aagaactgtt ccaactgccg aaatcaaaat aaaggcaata taaagacaaa
     8821 tgcttgcaat catagcggtc atcgtatttt gttcttcaat agcagaacct cttacagaaa
     8881 gtctataata ttgtacgact gtttcaccat catcatttac tattactaat cgatgtttca
     8941 aatcttgttt gattttttct ctaagttttg tatctgtttc ttctatggta tctataatca
     9001 gatgttgctc agatacttcc aagccttgaa catattcatc aggcacaata acagcaaatc
     9061 ttccagtatt atttatttga taccaatacg tttttgtatc aatgcccttt agttttaatt
     9121 cttttccact tgtcaactga attttttcaa tatccttgtt gttttcaact ttatataaca
     9181 aatctttgct agttacaaga aaatactcgt cattacttaa ttctatggtg tccatattct
     9241 ttaatttcag tatttcgtta taatcactta atttcattac tgggtcataa tcataaaatt
     9301 gcacgtcaaa ataattctgc atttgatgtt tcggttcttt ataaacatca aattcgattg
     9361 ctttatttat tgtataatct tcatcaacaa cattcacata ttctttaaaa tctttaaatg
     9421 gttgtttttc ttcaaacaca tgaacatcaa acggagctgt catttctatg cttgctttat
     9481 acactccttt attgatactt gaaaaattta aacataacaa agaaagtaat atcaacatgg
     9541 aaagtgtccc gaacgtaaaa ctcattgttc ttgcttttga cgcaaaagtt cttgttacaa
     9601 aaaggttatc tttttgatat ttaagttttt tatttttcaa taaaaccgac aacaacatat
     9661 ctgcacaagt agctgataca ccataaatac tgataatcaa catcatcatg ctaatcatca
     9721 aatacgtaag agtttcttgt ttaccgctgt tttccattgt ccaacgtgaa gcccaaagca
     9781 aaatagcagt aattcctaat ataacactaa caatgaaaat aatatttctc tttttattgc
     9841 tacggaacat tttcttttca ttctgcttat caaaataaag aaaatcatgt accgtcattt
     9901 ttctaattct tcgtaaaaga ttaagcagaa ccaatacgta tattgccaaa aagtaaatag
     9961 caagcaatcc tatggaaaca aaatttattg aaataaagat tacttctgga atacctaata
    10021 agtttacaat taccaatgat acaaattgac taaatatgaa cccaagagga atagccaaaa
    10081 ccaaagcaca tatcgctaat aacacatttt caattacaag caatcgagca atttcttttt
    10141 ttctaattcc aagaagcata tatgttccaa gctctttgct tcgcttttca aacataaatt
    10201 ttgtggtgta gttaatcaaa aaacagataa caaatataat aacaacattc acaaaagcta
    10261 gaatatactt aaacgtatcc atgcctgtcg ataattctat tacttcttca gaacttgcca
    10321 ctaagttaaa agcaaatata agagaaaatg cgatagtaac agttatcaaa taaatcaaat
    10381 aatctttaat gcttcttttt gtatttctaa ccgctaattt acctaacatt tcccacttca
    10441 cctccgagca aggttaatat atccagtatt tcattgaaga aatcttttct gcttttttcc
    10501 cctctgaaaa tttcattgaa tattttaccg tctttcaaga acaaaatacg tttacaaaaa
    10561 gacgcactaa acgggtcatg tgttaccatt aaaatagtag cctgcatttt cttgttgatg
    10621 tcagacattg tttccagtaa caatctggaa gattttgagt ccaaagctcc cgtcggttca
    10681 tcagctaata tcagtttcgg ttcattgatt aaggctcttg cacaagcaca acgctgtttt
    10741 tgtccgccag aaacttcata aggaaatttc gataaaatat cacgaatacc caatttatca
    10801 gcgatagcat gaactcgttt gtcaatatca gcagggttct gtttgttgat taccaatgac
    10861 aaagaaatgt tttcttcaat cgttaaggta tctaaaaggt tgaaatcttg aaaaatgaac
    10921 cctagatttt cacgtctgaa atcagcaaaa tctttatctt tgattttggt aatatcttga
    10981 ttgttgactg taatgtgtcc gctggttacg gtatcaatcg tagagataca gtttaatagg
    11041 gtagtctttc cagaaccact agctcccatt attgcgacaa attcgccctt gtctacatac
    11101 atagaaatac cgtctactgc ctttgtgata tttccagagt tacccccgta gtattttttt
    11161 acttgttcta aatttaaaat gtgttccatt aaaatcgctc ctttcttcct gccacattta
    11221 tttgttttgg aatacgatta aattatagca agggcagtat tcaattacac ttacagtttt
    11281 gaaagtaaac agagagtaaa agagccgtga taatgcagat cacaattctg tgaagcattt
    11341 tcacgacccg ttactttcat tgtctaaaaa attacaatta caaacctttt ataaatagtc
    11401 gtaagaaacc aattcttcca taggaatacg tgtagcaaaa tgacgttctg ggtctgctgg
    11461 tgtttctttc ccataaccaa tgactaatat attgactggt tctaaattat ctggtaattg
    11521 aaattctcgt ttgattacat ttggtttaaa aaagcatacc caaactgtac ctaatcccaa
    11581 ctctgttgcc tgcaacatca tgtggtctgt caaaatagta gcgtcaatat ctgttgtctg
    11641 tttgttatca aaaggtcgtt tccacgcttt tgaatggtct gcacaaacaa taattgccaa
    11701 tggagcatta tatatatttc cagcttttgc aatgcttttc aatcgttctt tgtcctgcac
    11761 caccaacaat ttaactggct gtaagttcgc cgcagttggt gcaacatgag cagaagcaag
    11821 tattttatcc agcttttctt tttctacggg cttatcttcg tatgttctaa cggaatatct
    11881 cttttttgca atatctaata cattcatttt tttaatctcc tttgttcttg tgaattaggt
    11941 caacctatac tataattata tccgtaatag tctattggac aagaacgcac tattttgtaa
    12001 tatactacct aaaaagaaag tgagagaaca tcatggaaaa taattgttgt ggttttagtt
    12061 gtcccgttga agcaaccatt caactaatcg gcggaaaata taaagcggtc attttatggc
    12121 acttaatgaa taaaacatta cggtatagtg aaattcataa gctcattcca aaagcaacag
    12181 acaaaatgtt agcacaacag cttcgtgaac tggaaaaaga cggattgatt aaccgtaagg
    12241 tttatcctgt cgtcccacca aaaacagagt attccttaac tgaatttgga aaaaccttaa
    12301 caccaattct tgatgaactt tgtaactggg gcgaaaatta tttactccaa aactgattgt
    12361 aagccgtgat aatcagattt ctcgctgtga gttgtttacc acggcgtttt tatttacagc
    12421 ttaacttttg tttttttcgt aatcttgtaa atatattctt ctggcgtagg acgtttattc
    12481 ccaaaatact ttttgaaatt tgcctgcacc tctgggtctg tactgttcat agcttcatca
    12541 atcgtcgctt caatatcagc ccgtatatca gctaaagaca caccgctagc atttgcacct
    12601 gctttcaatg ctttttttat atctcgtttt ttaagtccta tcaaaatatc actcctaaat
    12661 taaattttct gttacaccaa atgcggtata tttcctttca aatataccgc ataagaaaaa
    12721 ataaatcaat aaatgaactc tcttgattat cctacaatct tccagttact atccttatgt
    12781 agcacaagct catactgtga tacctgcgtt gcctttgtct gattatcgag gaatttcacg
    12841 gatactttga ctttcacatt gcccccgtcc tttgtaaaga tagggtttac cagttcagaa
    12901 taaaggtagt ccctgccgat aggttcaagc acatttcccg atacatagta ggcaagttct
    12961 ttttctgtgg ctgtcgggta cagcttaaag aatgtttcca gaaatgcggc agcgtcattg
    13021 acagtatcag cgtccacgct tgcgtcggtt tctggtgttt taggctcata gtctgatttt
    13081 tcgattgctg gtgcaagggt agggttctgc acgattacca tatccccgtc agcgtctaca
    13141 tggactttca cggtataagt tgccttgaca ttgcttgtct gttctccgtc ttttatctgc
    13201 tgatctactt cgtaggtggc agaaaaagtg tccgttcccg actgttcgat actccacaca
    13261 atcacatctg taaccgtgga gctggtcggt atatccattc tgattgtatc cacattcaag
    13321 tcctgcaatt cctttgtcag ataaccgctg attgcctgcg tccttgcttc aatcacttct
    13381 ttgctgttac tccatgtgta ataggacttc gcaaagttct ttacgaaatt ttctatcccg
    13441 ttggtgtcct gcaagcgaag ctcaatgatt tctttttcat gggtggtgtg ctggtcgata
    13501 gcggtaaaat tcttatacac cccaaagctc acgcttgcga taagcaccac ccacaacgca
    13561 atcacggttt tcttatgtgt gcctactttg acagtacgca ccattttttc tttgacattt
    13621 tctgtctgtt tcttattctt cttaaacata ttttcaagtc ctttctattg ttttactcgt
    13681 cctgcaccga ttaagtgctg ttgccagtaa ctactgctta ggtctgcata tcctatcggg
    13741 tcgcctgcat gatatatctg gttattccct acataaattg caacgtgcgt tacataagta
    13801 ccagcgttat aggtagaatg gaaaaacacc aagtccccag cctttgcctg cgaaagagga
    13861 agatgttggg tagcgtcata ctgtgcttgt gctgttctcg gtaaagagat accagctttt
    13921 ccatagcacc attgaacaag tccgctacag tcaaaagaag tgttgggatt gctaccgcca
    13981 tacacatatt tccagccttg atattttaac gcttcattca ttaccttttg tgccagctct
    14041 cccgatacct gcggaacagt taaatactga ttgactaatt cgacgtagaa catatttcca
    14101 tagccatacc gccagccccc gttcttcgca acggctatcg ggttggtgta ggttactttc
    14161 tttccacccg atttctcacg ggcgaaaatc tctgcaagat tgtatgtatg tttctttcct
    14221 ttacctgcca catagcccac atagccaccg ccatagttat aggactgtat cgctacattc
    14281 aaatcgtcga taccttgatt tttgcaggaa gaaagcaggg acgcaaaata cttacacccc
    14341 tgcttgattg aactttctgt atctaaggaa ttaggcggta aaccaagact ttccgaactc
    14401 tgcataacat cttctgccgt accgccactt tctacttgaa tgatagccag caatacattg
    14461 acatactcgg aaataccgta ttctttggca tatttttcca ccataggctg atgtttcaag
    14521 acttctgctg ataagttcat acccgtaatg ccagaagaaa aattgctgtt ctcgtcgtcg
    14581 ctgtccgcac taatgaggac accaaagaaa agcaccagag aaaagaggag aggaaacaga
    14641 ctgccgataa gagcgatatg tttcagtttc attttttctt ctgtcctttc ttcgttacaa
    14701 ggttacgggt tttctctgtg gtctgctggt tcttctggac gctctgggtc tgctgaacct
    14761 ttgtcctgcg gtctttggtg taattctggc gtgtttcctg cgataccact ttttctacat
    14821 tctgcctatg tgctatctgt gccgactggg tcgctttcct atcagaagca ccagaagata
    14881 acggacgctc tttgataaca gttgtcttga ctggctcact tgctttagaa gtggttgctg
    14941 tggcaggacg tttgacttcc tgcatttttt ctgcactcgg ctttggaatg gttgaagctg
    15001 tggctggtcg ctcatgggga cgggtagctc ccgttgtcgc tgatccgtca gcctttcgct
    15061 gtgcctgcct tgcttcttgt gccttttgaa gctccatacg cttgtcagcg atattctgcc
    15121 tatgctgttc ttgcctttcc aagcgtcccg tttgtctgga cagctgttcc tgcaccatgc
    15181 cacgcttaaa gtcggacacg ctggactttg ccttttcctt tgcggaatac accgcataag
    15241 cggtctgtgt cggcatatcc ttgatattct ctttgacagc atttgccttg tctttcactt
    15301 tatttttcgt atctaagaca gcccccacct ttgagcctgc acgctgtccc atgctggaag
    15361 tagatgtatt gccccgactg tcttttgtgg ctgtgttcct tgtcggtttt ctgtttgaaa
    15421 tcgtgctacc tgccaccgca ccagcaacac cgccagcagt aaccgcacca gcaagccgtc
    15481 tttccatacg cctagctcta tgtcgcataa acagatatgg tctgcggaat atcctgcgtc
    15541 ccatgttttg actgtcgcca gcgttcaaag agaacatact cattaagtcg cccagcttca
    15601 tgtagatacc agcgaaacac actatctgta agaaagctac catgaaaaac ggatagtccg
    15661 tggatatgtt ataaaacata ctggaaatgc tgaacgccac cgttacaatg agcgttattc
    15721 cggcccttgt cattatggta ttaaacaccc ttacgattgc ctgctttgcc atgctttcat
    15781 agctcggtat catagaaagt agaaaactga taggtaaaaa cattgcaaag ataataaaaa
    15841 gtatctggct aaacaacatc atgcccgtaa gcaagaatac aaatatcgtt atccctaaat
    15901 tgaagaacag taggaagaac accataccta aacggttcac gacctgcggt attgttagat
    15961 tgttgttgtc attgtcctcg atttctgttt tcacgacttc ctctctggtt ttcccgtcct
    16021 cgtcctctgg gcttgccgat acaagagctt cgacacggtc tgttccgatt tcctctgcgt
    16081 tgctgttacc gaattgcaga agtagccacg gctgttccac ttgaatagaa aataggctgt
    16141 cccgtatcaa gtccacgctg tctttgccct cgctgtcaga gttggggagc atgatttttg
    16201 ttcccaagtc caaagaagcg gtactgatgt cgcttgaaaa ctcatttatc tttttgatgt
    16261 agtcgggagc gtaggcaata aatgaagcgg acagcacgaa caccaccaca aagttgataa
    16321 cagcgtgaag tgccttgctt gtttcccgtt ttatcagtcc cgtataagca acataaagtc
    16381 ccaccaccaa gataataaga agcaggaaac cgacataaaa gcccgtggaa gaaaagccgt
    16441 tctgtgttac gcctgcaagg gtctgtatgc tctttccgat actgtctgcc atatcgttaa
    16501 taaaatcaag tttataggct tcctgcacca catagcccgt tgcattactc aaatataaac
    16561 tgatagtcca gacaaagttg gtaatgcaat aaagcccgta ctgtactgat tttccaatcc
    16621 cgtccagcca gttccacgga agccatgacc agctattatc tacataaaaa tcaagctggt
    16681 agttggaaag gggatatttt gagtaaagat tttctgcgtt tatggtatcg tccacaagcc
    16741 ccgtcgcatg agccaccgtc cccagaagtg aaagcaggat aagggagagt gccacgacaa
    16801 acagagccat tttgagaacg tgaagtatct tcttttttgt gaacgcacct tttatccttt
    16861 ctttcatcac tccacctcat ttctctgtac gggcggtctg gtatcaaagg cgtgtagcag
    16921 ttcttcaaag actgggtgta tctgcaccac accgacacgc ccgtataagt cctgcaataa
    16981 gcattgtccg ttttccaaat cacgcaagcg tttctggttg ttctcatcgt ccttgtcgat
    17041 accgaaaaac tctaaggtct gttttatctc gttgatgtcg gtgcttctaa aggcaaactt
    17101 caagccgata ttgtttttca gactttcttt tgacacgtcc ccagaagatt gtgtaacaaa
    17161 ataaacgcct gcctgcatag cacgtccagc acgaaccagc ttatttgata aagtttcgcc
    17221 ttgtgccacg tttaagaacg cccacgcttc gtccaaatcg acaatcttaa aaatgcttct
    17281 gtctgaatgg ataaaatcaa gagcaaaggt actaatcaca atcagcatag acaccgacaa
    17341 taattcaatg gtcgtgtatt cctcaaaggt cgtgtcctta tctggcaata ctaagtccgc
    17401 tacttgaatg atattgagct ggttatcaag gctgatagca ttttccaccg taccgtctga
    17461 aaacagcagg tgtgcaaagt cgtagtccgt gaagctgtcg atatggtctg cgatatttct
    17521 tgatactggc gtatcttcac ggcgtaactc gtctatcaca tgaagcaagc cccgtttgtc
    17581 gctctgggta acggaacgca ccgccttacg aagtacgggg aacttttctc cgtcccttga
    17641 agaaataccc gtaaggaatg ttaagatgtc gattgccaga ctttcagcgt cttttacatt
    17701 cttcataatc acaaacgggt caagaagtcc tgcattgtcc ttgtcgcttg ttaggtttac
    17761 gatattgatt tcatgggcga tttctgggag cgtttctttc cagttgccac gctcactttt
    17821 agggtctaac agaagtgctt gaccgccaaa cagcaccgaa taatacacca gaagattgtt
    17881 acagaacgat ttcccaccgc caagcgaacc gacaaaagca gacgctaaag cgttggtaac
    17941 tgtacctttt acaccttgac tggcaaggga cggttgcagg tacacatttc ttcccgtatc
    18001 aacagaatag cccatataga tacccgtagt ttctcctaac tgctgtgtcg caccaaaacc
    18061 aagccctgct agaaaatctg attttacata ctgcacataa tcattgatat atcgcttgct
    18121 ggctggtaaa aattcagaat gaagccccag catatcccca gcaggacgca ccagctttac
    18181 attgaggtcg tcgtaaaagt ccttgacttc atcacaacgg cgtttcagct cgtcaagatc
    18241 gggtgcagac acccgtatga cgtagcttaa cttatacata ctttctttgc tctggtctaa
    18301 gtccgtttcc agctcgtcca cgctatctaa tgcgtccacc acatttgagc tggtttcact
    18361 tcctgcttga taagcgtgat tgtcaaggtc tttcaattcc tttttcttgt tgcggactgt
    18421 cgttaatgct ttccgatttt ccacgatttc tacattcata gaagtatcaa cggggaatgt
    18481 gaattgctgt tgctggaaat agaagatttc acttgacgga aaatcaagct cgccgacaat
    18541 cgcattgacg gtaaaatagg acacatagct ttccttgtcc tcatgttcca atcttaaata
    18601 ccgctggctt tcctcaatca cacaccttgt cggacggata aggtcgtagt attttatcag
    18661 cgtttctttg ttcaatttct tctttggtag ctggtactca taatcttcat aagcgatacc
    18721 gtccctgccg taaagatgtt ccatgagata cccaaaatca ttgatttcca agcgacgcac
    18781 cttaaagcga cgggagattt tattttccag taacttttcc attttcatgt aacggttgat
    18841 ttcatcattc ggcatggaaa caaaatcatt catcagcgtg tggttcactt catgaagaaa
    18901 ttctgtgaac gtcagccacg ccgatttttt gatgttcttc agattgagct gttcttccgt
    18961 aaccatgagc ttaaagccaa gaaaaaagcg gtagtccact tgattgtccc caatcataga
    19021 tactaacgct tcggtctgtt cgtctatctt ctgataggca acttccttta attttccagt
    19081 taccagcttc tttgactgtt cctgcatact gcggattgag ctttctgtgg caatctgcaa
    19141 cgcatgaatt ttaccctcac gggactgtgc gataagctgt cggaaactgt catgcacgat
    19201 aaatttctgc tctgcggata agaaagaata gttgtacggt atcagctcat agtaggcgaa
    19261 tacctcattg tccttgttcc agacaaggtt attgttaata tattttatcg ggaacatagt
    19321 tcacactcct tactgccgtg attgtttcat tgagtatctg cttatgcagt tttacggctt
    19381 ttcctgcata agtgatttta ggtcgcaggg cataggttat ctgtgatttc aaaaagctgt
    19441 acggcttctt tccgtcaaag gttttctgcg acataaacca agtgagagca acgggaatac
    19501 cgaagtattt gagaaatgct ccctcaatca tggaaagtgg gggaatatcc ccaaacagaa
    19561 tgatgataaa ttccgtaatc acaaaccatg taatctgtgt aaaggtaacg ggaaagggca
    19621 agttaaagtc attgattgca tacaagactt tttccacgtt ccagataccc gtataagatt
    19681 taatcttttt caagttcttt cagctccttt caaaatagaa aaggacagcc atgtttcaga
    19741 ctgtccctta aaagagaaat acgctgtcag tagcaacaat gcttgtcgct gatcttccag
    19801 cgttagtatg gtatctcgca catacctcgg cttgtttcaa taaagtaacc gcccatatcc
    19861 aaatctcgcc cgtaggcttc atagtcaatg tagttctgta agctgggtgg aatgtcgcca
    19921 agtgcctgca attcgtctat gtagtagtag gcaacatctg tcatggtttc acagtcggga
    19981 taataataaa tatcgtcctt gtgttccacg acttcttcca gagtcccgta gtggctgata
    20041 aattcgtcca gacactctac gatatagtcg ggaagttcct ctatcatttc atacatctca
    20101 ttaagttctt caatggaaac atactcgcca atcgcaatgg gaaagttatc ggtatcatgg
    20161 attgcgtatt cctcatactg ttcattcaat ccgatttttt ctttcacatc ttcctcgtca
    20221 atggggaacg tgaaccaagc accaactaaa tagccctcat tgtatttgcc aagattagca
    20281 atgtaaaccg ccatatcatc aatcataagc accacctcat ttcctactct ggcagttcaa
    20341 aaataccgtg ttctgttact aaaaatttcc cgtgttcctg caagtgagaa gcgtaggctt
    20401 caaagtcaaa atagtattct tgacagtcct cggataaatg tttgaacgtc gggtcgttca
    20461 tcagcttttg ccttgcaaca tctatcatgc ttttgcagtc gggataaacg gtaatcacgt
    20521 tcctgcaaat ataaagtgct tctaaatttt cacacacggt aagaagtgct gtatattctt
    20581 cctgcatatc gcttgaaagc tggcggtaca taaaatctaa ttcgttgagc tgatacacac
    20641 ttgtatgttc gtggatttca tcagcaaagg gcagtacctt ttcgataata caataatctt
    20701 gactttctgc accgacacct aacttttctt caaactcggc aacatctatc ggcaggtcga
    20761 accagtatga tgttgtttct tcgccagttg ttcctttcgt ttccaccagc acccttgttt
    20821 cctgcattgt tcctcacgtc ctttctgttg tttcatcaca tcttttaagg tctggtacga
    20881 cataccaaac acatatttag aaaaatcttc taactgtctt tcttcatgat cggcagggtt
    20941 cagtcgtttc atttcatgcc acaccttacg cttgtaagag ggcaggtcgg aaagataatc
    21001 acagccgact tttgcctgca tatccttaaa aatatcgttc atttcatcac tcaaatctga
    21061 aattttggta agaaaaaagc agtcaatcct aagactaact gctttgtgtg tatagatata
    21121 atttgattaa gttttaaaac cagcttattt tttcatctct aaattgaggg ctatcgctgt
    21181 gctgatatgg attgtagtta ttcaaattgc aaccatattc ttttaatgat ttgattttgt
    21241 tatcttctgt ccattcaatt aaggaaatac cgtcaaattc ttcaacactt cccgtattca
    21301 tttcattttt aaaataccat tctacgacag tttgattttc tttatgaaag aactgtttaa
    21361 tatcccaaat aatgacttta ccacgagtat tccattcatt aaaccaatgt tttactgttt
    21421 taagattttt atatttagga caccaacttt ccgtataaac aacatcttct gtaaaaattt
    21481 tatccattcc taaatcttgc tgtttaagcc acatatcgaa ccataagcga atgatttttt
    21541 ctctctcatt cataataaaa cacctcaatc ctaagaccaa ttactttgta aataatgaag
    21601 ttgaaaattt attttataga atttttgcca tataaaactc atcaacaaag gaaccagcaa
    21661 caaacattga tttttttctt attccttcaa ttttaaaacc atttttttca tacaaatttt
    21721 ttgcagtatt attacaacat tcaactgtca gttccaaacg gacaatatta tttgttttag
    21781 cccataaatc taaattatta aaaaaagtag ttccaatacc ttttcctcta tattttttta
    21841 agatacctat aacaatatat gcagtatgaa aatttctttc aaattttcct ctttctgctc
    21901 taatataacc aactattttg tcattttctg ttgccacttg caaaaaatca aaaccttgaa
    21961 ttacattgtc ttgaatatct aattttaatt cttgaatagt agttttcgct tttctttcat
    22021 ttggttcgta catcatgtaa tctgtttcag tatctaaacg atttaataac tcccaaaaat
    22081 cttttattct attgatttcc aatttgctat aaataatcat attttcaacc tcaaatcgta
    22141 ttcactttat ttcatattct aaattatacc attctcatat cagcacaaca ataaaatttt
    22201 atgcaccgat aatcttattg aacagctcta acagtacatc tttcacaccg ccagcgttga
    22261 ataccaaacc aacagcaatc aaggcaacta ccaagaagcc gataagtttg gaaaactcac
    22321 gcttgaaccc taagtagata ccgataacca cgattgccat aagcactaag ctctgtgcgt
    22381 ttgataaaaa ccattg
//
LOCUS       DAMKNB010000060        21906 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.062, whole genome shotgun sequence.
ACCESSION   DAMKNB010000060 DAMKNB010000000
VERSION     DAMKNB010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 21906)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21906)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21906
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.062"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            177..833
                     /locus_tag="PC494_002539"
     CDS             177..833
                     /locus_tag="PC494_002539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3913030.1"
                     /translation="MKKGDFIWSGVLICIIAVLAIPSSREVFMEATGAHPYIGGFLKF
                     AVLATMGDLLGARILYKDWKIPVGVFYRAIVWGIIGVVTTYGMSIYSSGVGQAQVDGM
                     LPFEGIAFANALFKSATMNILMSPTVFLFHKIMDCFIDKKYEVGKGIKVKLKDVVNIV
                     DWNAYLGFSVLKTIPFFWIPCHTIVFLFPAEYRVIASAFASIALGLILALANKSKVAV
                     "
     gene            complement(1310..2581)
                     /gene="sleC"
                     /locus_tag="PC494_002540"
     CDS             complement(1310..2581)
                     /gene="sleC"
                     /locus_tag="PC494_002540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore cortex-lytic protein SleC"
                     /protein_id="HDF3913031.1"
                     /translation="MQDGFLTVSIIDATNNRPIQNAVVNIYSMSNGSQSSSTLYQNLR
                     SNESGQVTGLVLPAPDVDYSLQPSDVRPYSQYIVEAIADGYETVVIEGTQLLATIEAR
                     QGVPMSPRTRSKRSFSRQSELIFDIGEHTLYGTYPPKIPESNLKPLPPPTGFVVLDNP
                     VVPEFIVVHDGLPEDSSAPNYWIPFKEYIKNIASSEIYSTWPEQTIYANVIAIISFTL
                     NRVFTEWYRNKGYNFTITSTTAYDHKFINNRNLFEPINVVVDAIFNTFIKRPPTSRQP
                     LLAQYCDGQKSQCPDQMTQWGSKDLGDQGYDYESILRYFYGDEIVFERAPIVSGVPVS
                     FPGTTLQVGSSGQYVRTIQNQLNAISNSYPAVPKVIEDGIYGTDTENAVKIFQGIFGL
                     PQSGVVDFKTWYEISRVYVATTRIASLNPLI"
     gene            2826..3542
                     /locus_tag="PC494_002541"
     CDS             2826..3542
                     /locus_tag="PC494_002541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrsW family intramembrane metalloprotease"
                     /protein_id="HDF3913032.1"
                     /translation="MKLDLFLLAIVPILIGMFWIRSKDRYCREPLIHLIKFFLIGAFL
                     SVIIILLENLLMKFNVFEGYSELIYVSFVVAGLVEEGVKALILIPALIKEKHFTEKLD
                     GIIYSVFLALGFATIENMVYIFSESRNLALQVGINRAVISIPAHVMFAITMGYYISKY
                     KFEGNKNKRREYLFMAVLIPILLHGVFDFILMIEYRWAIILLIVYVIILWKINLDKLE
                     KYMNHSKKVFFGNLRKKKKK"
     gene            3621..4931
                     /locus_tag="PC494_002542"
     CDS             3621..4931
                     /locus_tag="PC494_002542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmB/NOP family class I SAM-dependent RNA
                     methyltransferase"
                     /protein_id="HDF3913033.1"
                     /translation="MTELPKEFLEDIEEILKDEYDDFIKSYEESKTTGLRINTLKIDK
                     KKLFDLELFDLNQIPWAEEGFYYDDKIDRPGRNPLHEAGAYYLQEPSAMSVIPKADIK
                     EGEKVLDMCAAPGGKSTYILSKLNDTGLLVSNEINASRIKALGENLERFGARNCIITN
                     TDSNSLRKTFNGYFDKVIIDAPCSGQGMFRKDEVAISDWSYAKVVECQSIQKEIIRDG
                     YKMLKKDGILIYSTCTFSREENEHVINEFISEYPHAELIEMERLWPHKIKGEGHFVAK
                     IKKLEEEECNVKELKIKNLDKEIKDYREFEKKFLKVDFYSNKKNKFYLRGENLYLLPE
                     IYPDTKKLKVLRYGLHLGVLKKNRFEPSHALSHYLKVEDVKNVENFSVQSESILKYLK
                     GDVVNSNDSRGWVLVSVEGIPLGWGKESSGVIKNHYPKGLRKVF"
     gene            5031..5567
                     /gene="lepB"
                     /locus_tag="PC494_002543"
     CDS             5031..5567
                     /gene="lepB"
                     /locus_tag="PC494_002543"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HDF3913034.1"
                     /translation="MGEAVKKEVVEWIKVIVIALVLAFAITRFIVPTIVKGESMYPTL
                     VERDYLIVNRIAYKVGEPKYKDIIVFKTDLTEENGKKKDLVKRVIGVPGDHVKIQDSK
                     VYVNDKLLDETSYIHNNRTDGDIDIVVPEGKLFAMGDNREKSLDSRYDEVGLVDEHTI
                     LGKVLVRLYPFSKIGTID"
     gene            5733..6269
                     /gene="lepB"
                     /locus_tag="PC494_002544"
     CDS             5733..6269
                     /gene="lepB"
                     /locus_tag="PC494_002544"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HDF3913035.1"
                     /translation="MNETIKEEIVEWIKIIITALFFAFIITRFIKPTLVNGESMYPTL
                     KSHDYLVANRMTYKLSEPKCGDIMIFKTDLLQENGRKKELVKRVIGVPGDHLKIKDSK
                     VYINGKLLNEVSYIHDNYTEGDIDMVIPKGKVFAMGDNREVSLDSRYKEVGLVDEENI
                     KGKVILRVFPFTDIGIFE"
     gene            6279..7034
                     /locus_tag="PC494_002545"
     CDS             6279..7034
                     /locus_tag="PC494_002545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIM barrel protein"
                     /protein_id="HDF3913036.1"
                     /translation="MAVGIASLLFNIEEALNICESIKQITHLEIGIDNISECSELCKY
                     KERISKLGLSIGIHLPMELNTCENIEYIRNSWINFIEKIEFELKGFDLRYFNLHLGYV
                     MTNRVRKNRDKYLGNSVDFLDKLNTNSYVCIENTYSKGGDFSNIGNISYDFEYIFKRI
                     KNSKICFCYDTGHCLIDEDAYVKNLKDKIRLIHLSDNDGINDTHVGIGRGILSEEGIK
                     EVLTLDAEYLVLEINYEDIEDTISKLNNIVGEG"
     gene            7108..8775
                     /locus_tag="PC494_002546"
     CDS             7108..8775
                     /locus_tag="PC494_002546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside kinase"
                     /protein_id="HDF3913037.1"
                     /translation="MKKINLKIEGKDKEYSLEENSPGIRLGDIAKEFCDEHKGYITLA
                     VVDNKLKELNCRVKKDCEINFLDTTNEDGERVYFRVMSFIFVMACREIFWDSRVTIEH
                     SLSDGLYCEVHIDRKLKEADVENIKNKMKEIVNNDYVIEKIEVTRNEAISIFENNEMY
                     EKAELLKYKEYDSAKVYKCRNYIDHFYGYMLPSTGYIKSFDIKLYNGGVIILGPSEED
                     KTLPMKFVPQPKLSSVYYEAEEWSRLMGIDKVVSLNKIIENNEYGDIIRTFEALHEKK
                     LSQIADMIKDGNKRVVLIAAPSSSGKTSFAHRLSIHLRVNNLNPISISLDDYFIDRKH
                     TPLDEYGNYDFESIYAIDLEKFNLDLKKLLAGEEIDDIRFNFKEGKREYTGKKIKIDS
                     NQPIILEGIHGLNPILTSSIPDEDKFKIYISALTQINLDDHNRIPTADLRMIRRIVRD
                     YNFRGYSADNTILQWASVRRGEKKNIFPYQEEADAIFNSACVYELAVLKRFAKPLLEE
                     IKEDNPAHIEATRLLKFLQYFVELDDTSDIPGISILREFIGGSKIVD"
     gene            9678..10607
                     /gene="glsA"
                     /locus_tag="PC494_002547"
     CDS             9678..10607
                     /gene="glsA"
                     /locus_tag="PC494_002547"
                     /EC_number="3.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaminase A"
                     /protein_id="HDF3913038.1"
                     /translation="MNTLDETLLKEIISSNKKYTNYGQVASYIPELKNARRNDLGICI
                     IDSENNLYSAGNCSTKFTIQSISKPIVLAMALMDNDWEDVFSNVGMEPSGDPFNSIMK
                     LEINDTKKPCNPMINAGAIVTTSLINGSCLEEKEERMLSFFRKLAKNDNIGINYDVYK
                     SEKMTGDRNRAMAYLLKSDGFIRGNVEDVLDLYFKQCSIEIDSVDLARIGINLANYGV
                     DIENGEHLMSEMVSRIVKTFMMTCGMYDASGEFAIKVGIPAKSGVGGGIMASVPGRMG
                     IGVYGPALDKKGNSVAGVKVLEELSNKLKLNIF"
     gene            10705..11268
                     /locus_tag="PC494_002548"
     CDS             10705..11268
                     /locus_tag="PC494_002548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF3913039.1"
                     /translation="MKEVLVLRDLECIKAIAHPRRIDILKAFDKSPLSAKQLSQLLEE
                     PHAKINYHIKMLYKVGILELVEEKIKSGIVEKYYYPSAKNVVIGNRILNFSLDNGEEK
                     EELYISKFENMSEVFYKAAEEDVLENENIVDYHDISLTHDELVELSDTMKSKIDEILN
                     KRQHNVEGSKYDIAMVIVPTLEEECPS"
     gene            11756..12592
                     /locus_tag="PC494_002549"
     CDS             11756..12592
                     /locus_tag="PC494_002549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribonuclease IV"
                     /protein_id="HDF3913040.1"
                     /translation="MIKLGTHLSIAKGFANAAETAVYIGANTFQFFSRNPRGGNAKEF
                     DEKDIIKFQEIRKENNFAPLLAHAPYTMNLGGTKDDVYEFATRVIDEDIRRMDSLGIE
                     YMCFHPGSHVGGGVDFGIDRIVKGLNNAIKGDENITILLETMSGKGTEIGFKFEQLKS
                     IIDKIEHKEKIGVCLDTCHIFSAGYDIVNDLDGVLEEFDKVIGIERLKTVHLNDSMMP
                     FGDKKDRHAPIGEGKIGLKALIDFMEHPSLKHLPFFLETPFDDEGHKRELKMIKEILS
                     SK"
     gene            12876..13871
                     /locus_tag="PC494_002550"
     CDS             12876..13871
                     /locus_tag="PC494_002550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HDF3913041.1"
                     /translation="MRNLGNTNMKIKRVGFGGIPIQRITQDDTNLVINELEKQGINFI
                     DSARGYTISEEAIGIAIEGKRDKFFLATKSMSRDYDSMKRDVEISLNNFKTDFIDLYQ
                     FHNVKEEEYDNLFKDKMAYSALLEAKEQGKIKHIGITSHNLNTIEKAIEDGKFDTIQF
                     PYNIVEGQADEVFKKAHEKGIGIIVMKPLAGGALDNATLAIKYILSKEYIDVVIPGME
                     SVEQVRQNVAVLENLVLDEKDNKEIEEIRNSLGKKFCRRCEYCMPCAVGINIPLSFLC
                     EGYYTRYGLKEWAKEKYEVMDVKPTECIDCGLCESRCPYELPIREMLKTVVEKLG"
     gene            complement(14128..14532)
                     /locus_tag="PC494_002551"
     CDS             complement(14128..14532)
                     /locus_tag="PC494_002551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RusA family crossover junction
                     endodeoxyribonuclease"
                     /protein_id="HDF3913042.1"
                     /translation="MIKITIPGRPISKSNFKLHNINGQAWMPSKGKYSKYLAYENMIA
                     GFINQQYQGETVEENLITVLKLFFPNKRMGDLHNYPKSICDGIEKSGIIKNDKQLKPV
                     LLFDFIDKDNPRVEIELYPVSKYDISYNIFEK"
     gene            15629..16543
                     /gene="queG"
                     /locus_tag="PC494_002552"
     CDS             15629..16543
                     /gene="queG"
                     /locus_tag="PC494_002552"
                     /EC_number="1.17.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA epoxyqueuosine(34) reductase QueG"
                     /protein_id="HDF3913043.1"
                     /translation="MDNKELKAFCNLIGLNCVGVAGVDKYDNLEKILKDRQQKGYLTG
                     MEEPIIENRINPRHIMKDANSIIVCAFPYHINRQEKNKNSNLSKYCHGKDYHIVVKDF
                     LQQICDYISKTVTDFKYKLFADNGPLVDRYLAYLSGIGYFGINNNIITDEYGSYVFIG
                     YIVNNYKFEEDKPLEKSCFKCGKCVKYCPGNAILGNYDMNPKKCLSYITQKKGDLSEK
                     EKVVLKNGKKVFGCDICQEVCPHNVEIPTTHILEFKENIIDYLDYDEIQNISNKEFKR
                     RYGDRAFSWRGRNIIKRNMEIILDKYDD"
     gene            16649..18886
                     /locus_tag="PC494_002553"
     CDS             16649..18886
                     /locus_tag="PC494_002553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HDF3913044.1"
                     /translation="MKYNNTSEINPLDYILGQERAVEAMELGLKINNPAYNIYIAGEP
                     GTGKSTYALKVLNEYASKKNTHKDWCYIYNFENPREPIIVELEKGFGRELKKDMEKLI
                     ESLLEDFKNAFESENFEIEKNKLLDEYEIEKDMLLKQIKKYGEEKGFKLKQSKMGIVF
                     IPLKEEEDESDESDEEFYKAKRELENMAIQVVYKIRNLEEIAEKAVLELEEEIAKLVV
                     EPHIKRLCEKYENYDKIQTYLENIKKDIIEYMYLFYLDEEELKDKYDKEHFIKYKINL
                     FVDNGSSKNKESAPVVVEINPSPANLFGKAEYDYANGNIKTDFTKLLSGAFHRANGGY
                     LVLYADQLLKYTMSWEILKKTLQTKKVILETQTAIKPENMPLDVKLVLIGSHYIYDIL
                     YRYDEDFEKYFKVFVDFDSEMDKNEDNEEGIARFIAYQCDKNNLRHFTKSAVEEVIKF
                     STRLSGDLEKLSTKFNKIMEVVIEGSAYAEFRNSEYTEQCDVKKAISEKRKRINRVET
                     HMDESIENGFTLIETEGRKVGVINGLSVLSTGEYSFGRASRITATTSPGSKGIVNIER
                     EVNMSGSIHNKGVLILGGYLSENFAQDLLLSLNAYVCFEQNYGGIDGDSASSAELYVL
                     LSSLSGVSIKQNIAVTGSINQKGDIQVVGGISEKIEGFYSICKTKGLNGEQGVIIPRK
                     NQRNLVLSDEVNDAVRDGKFKIYTVERVEEAIEILTDVKFEEIKKLVKEKLISFSKIQ
                     TVSKE"
     gene            19083..20135
                     /gene="nth"
                     /locus_tag="PC494_002554"
     CDS             19083..20135
                     /gene="nth"
                     /locus_tag="PC494_002554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HDF3913045.1"
                     /translation="MKNVNLKEINEKDVIVEEDINLKGMDKKDVIEKEEVNKKSIDKK
                     DIIEKEEIDKKNVKKVEVQKGIDKMIGKKDEIIDEKDIENFMDIEEDKKSIKVSKKST
                     KKGETEKKTKKSSSNKATQKTSKETKSKSKIKNESANEKDVNKILDELEKLYPDAKCE
                     LNYGTAFELLIATILSAQCTDVRVNKVTSELFKKYNTARDFANLSIEEISKEIKSCGL
                     YKSKSQKIKDTSEQLCELYDGEVPDSLEKLIKLPGVGRKTAGVVLSNAFNHPAIAVDT
                     HVFRVSNRIGIVDEPNPQKTEFALMETIPKERWSHSHHVLIFHGRRMCKARNPECASC
                     PIKEDCNYYKELNETK"
     gene            20329..20799
                     /gene="trmL"
                     /locus_tag="PC494_002555"
     CDS             20329..20799
                     /gene="trmL"
                     /locus_tag="PC494_002555"
                     /EC_number="2.1.1.207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (uridine(34)/cytosine(34)/5-
                     carboxymethylaminomethyluridine(34)-2'-O)-
                     methyltransferase TrmL"
                     /protein_id="HDF3913046.1"
                     /translation="MSLNIVLVEPEIPQNTGNIIRTCAATGSTLHLVKPLGFSLDDKH
                     LKRCGLDYWDIADIQYYDSFEELQEKYPNSKYFFSTTKAKQSHSDVKYEENCFIVFGK
                     ETKGLPEPLLKANMDTCIRVPMLDVEKARSLNLSNSVAIVVYEALRQIGYPNMR"
     gene            20835..21683
                     /locus_tag="PC494_002556"
     CDS             20835..21683
                     /locus_tag="PC494_002556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HDF3913047.1"
                     /translation="MKNLKIICDSLSDVPKDLLDKYDIDIVSLTVILEEREYKDRIDI
                     SGDEFYKRLREENVYPKTSQATYAQFKEIFEKYTNEDREILYIAGSATATGTYQSAVM
                     AKNDVDGKIYTYDSNLLCMGTGLLVIKAGELASEGKSVAEILPVLDELKEKAFVIFSV
                     DTLEYLQKGGRISSTKAAIGSILNIKPILEIRDGLVSQISQVRGKKNVISKMMELIKS
                     NCGDDLSDQIVYIGYSDDFKEKEQLSKVMQDELRPKEIRFFQIGVCIGAHAGPGVTGI
                     ICLKNK"
BASE COUNT         8648 a         2072 c         4076 g         7110 t
ORIGIN      
        1 gataatggta gatagagtag taagaaaata aatagataaa gggatagaat aaatttaaat
       61 atggaaaatg aatatctaat aataagtgat taataaataa ttgtagatag attgtaaatt
      121 aaataaatct ttaatagaaa ggagaactat ttatatatta aatagtattt ataaatatga
      181 aaaaaggcga ttttatatgg agtggagttc ttatttgtat tattgctgtc ttagcaatac
      241 caagtagtag agaagtattt atggaagcaa caggtgcaca tccatatatt ggaggttttt
      301 taaagtttgc tgtattagct acaatgggag atttacttgg tgctagaatt ttgtataagg
      361 attggaaaat accagtagga gtattttata gagcaatagt ttggggaata ataggtgtag
      421 ttaccacata tggaatgtca atctactcat caggtgtagg tcaagcacaa gtggatggta
      481 tgcttccatt tgagggaata gcttttgcaa atgctctatt taagagtgca actatgaata
      541 tactaatgtc accaactgta tttttattcc ataagattat ggactgtttt atagataaaa
      601 aatatgaggt tggaaagggg attaaggtaa aacttaaaga tgtggtaaat attgtggact
      661 ggaatgctta ccttggtttt agtgttttaa aaactatacc atttttctgg ataccatgtc
      721 atacaattgt atttttattc cctgctgagt atagagtaat tgcttctgca tttgcatcta
      781 tagctttagg tctaatattg gctttagcta ataagtctaa agttgcagtt taggttcact
      841 gatgaagata atagtattat ttaaattagg aataactttt taaattaata ttatttgtat
      901 ttataataaa taataattta tataagaagt aatattctaa gtgatggata gtgttttaaa
      961 taataagaag taatactcta agtgatagat agtgttttaa ataataagga gtaatactct
     1021 aaatgagaag tatcatttta aataataagt gagattttaa ataataagta ggtttttcgt
     1081 tagaatagca ttttattaaa cttaaaaata aatataatat tttaaagaaa tctaagttgc
     1141 taagcactgt ttttaagatt ctaaaaaaac aagttataac taaaaaatgg ctgttaagac
     1201 tacaatactt ataagtaata cttatggtat atattagttc ataacagcca tttttatttt
     1261 aaattaataa ttttattcaa taatttgagt ttatgttcta aatcaagctt taaattaaag
     1321 gatttaaaga agctattcta gttgtagcta cataaactct ggatatttca taccatgttt
     1381 taaaatctac tactccgctt tgaggtaaac caaagattcc ttggaatatc ttaacagcgt
     1441 tttctgtatc tgttccatag ataccatctt ctataacttt tggtacagct ggataagaat
     1501 tagatatagc atttaactga ttttgtatgg ttctaacata ctgcccagaa gaaccaactt
     1561 gtaatgtagt accagggaat gacactggta caccacttac tataggcgct ctttcaaata
     1621 ctatctcatc tccatagaaa tatcttagta tactctcata gtcatatcct tggtcaccta
     1681 agtctttact gccccattga gtcatttggt caggacattg ggatttttgt ccatcacaat
     1741 attgtgctaa tagtggctgt cttgatgtag gaggtctttt tataaaagta ttaaaaatag
     1801 catctacaac tacgttaatt ggttcaaata agtttctatt atttataaac ttatggtcgt
     1861 atgctgttgt tgaagttatt gtaaagttat atcctttatt tctataccat tcagtaaaga
     1921 ctctatttaa agtaaatgat attatagcta ttacatttgc ataaattgtc tgttcaggcc
     1981 aagttgaata tatttcagat gatgctatgt ttttaatgta ctctttaaat ggaatccaat
     2041 agtttggagc tgatgaatct tctggcaaac catcatgaac tactataaat tcaggcacta
     2101 cagggttatc taatacaacg aaaccagtag gaggtggtaa tggttttaag ttactttctg
     2161 gaatcttagg aggataagta ccatatagag tatgttctcc tatgtcaaaa atcaactcac
     2221 tttgtcttga gaaagaacgc ttacttcttg ttctaggaga catgggaact ccttgtcttg
     2281 cttcaattgt agctaacaac tgtgttcctt ctatgacaac tgtctcatat ccatctgcta
     2341 tggcttccac tatatactgg ctataaggtc taacatcaga tggttgtaga gagtaatcta
     2401 catctggtgc tggtaatact aaaccagtca cttgaccaga ttcattactt cttaggtttt
     2461 ggtataaagt tgatgagctt tggctaccat tagacattga atatatgttt actactgcat
     2521 tttgaatagg tctattgtta gtagcatcaa ttatgcttac tgttaagaaa ccatcttgca
     2581 tcaaatcacc ctttctttaa atgaatttag ttcccttata tttcaagata tgaatatagc
     2641 ttaaaatttg ttaaataata tagatataaa tttaaatttt tttgagtatt tgagtatatt
     2701 tgtatttaaa taatttaaaa taatttaatg tatattttag tatgtattta aaacacgaat
     2761 aagttaaaaa taagtagatg atataaatca taaataaatc aaaaattttg aaaggaaaat
     2821 aatctatgaa gctagattta tttttattag caatagttcc tatattgata ggaatgtttt
     2881 ggataaggtc taaagataga tattgtagag aacccctaat ccatctaatt aaattttttt
     2941 taataggtgc ttttctaagt gttataatta tacttttaga aaatttactg atgaagttta
     3001 atgtatttga agggtattca gaactaatat atgtatcatt tgtagttgca ggacttgtag
     3061 aagaaggtgt aaaagctctg atactgattc ctgccctaat taaagaaaaa cactttactg
     3121 aaaagttaga tggtattatt tactctgtat ttttagcttt aggatttgca acaattgaaa
     3181 atatggttta tattttttct gaaagtagaa atctagcact gcaagttggt attaataggg
     3241 cagttatctc tataccagct catgtaatgt ttgcaattac tatgggctac tatatttcta
     3301 agtataaatt tgagggaaat aaaaataaaa gacgtgagta tttgtttatg gcagtgttaa
     3361 ttccaatttt attacatgga gtttttgatt tcatattgat gatagaatat agatgggcta
     3421 ttatattact tatagtttat gtaataattt tgtggaagat aaatcttgat aaacttgaga
     3481 aatatatgaa tcactctaaa aaagtgtttt tcggtaatct taggaaaaag aagaagaaat
     3541 aaaatttaaa ggaaagacat aaataattaa agtataataa atgacacaca agtaaagcag
     3601 attgaagggg gattatagat ttgacagaat taccaaagga atttttagaa gatattgaag
     3661 aaatactaaa agatgaatat gatgatttta taaaaagtta tgaggaaagt aagactactg
     3721 ggcttagaat aaatacttta aaaattgaca agaaaaaatt atttgatttg gagttgtttg
     3781 atttgaatca aataccatgg gcagaagaag gtttttatta tgatgataaa attgacagac
     3841 ctggtagaaa tccactgcat gaggctggag catactattt gcaagagcct tctgcaatga
     3901 gtgtaatacc aaaggcagat attaaagagg gtgaaaaagt tctcgatatg tgtgctgctc
     3961 ctggtggaaa atctacatat atactatcta agctaaacga tacaggttta ttggtttcta
     4021 atgaaattaa tgctagtaga attaaggctc taggggaaaa tttagagcga tttggagcga
     4081 gaaattgtat tataacaaac accgattcta atagcttaag aaagacgttt aatgggtatt
     4141 ttgataaggt tattatagat gcaccttgtt ctgggcaagg tatgtttagg aaggatgagg
     4201 ttgccatatc agattggagt tatgcaaagg tagtagaatg tcaatccatc caaaaagaga
     4261 ttataagaga tggatataaa atgttaaaga aggatggcat tttaatttac tcaacttgta
     4321 ctttttcaag ggaggaaaat gagcatgtta taaatgagtt tatcagtgaa tatccacatg
     4381 cagaacttat tgaaatggaa agattatggc ctcataagat aaagggagaa ggtcattttg
     4441 ttgccaaaat aaaaaaatta gaagaagaag aatgtaatgt caaagaatta aaaataaaaa
     4501 atttagataa agaaataaag gattataggg agtttgaaaa gaaattttta aaggttgatt
     4561 tttatagtaa taaaaaaaat aaattttatt taagaggaga aaatttgtac ctacttcctg
     4621 aaatatatcc agatacgaaa aaactaaaag tattgagata tggtttgcat ttaggggttt
     4681 taaagaagaa tagatttgag ccttctcatg cactatctca ttacttaaaa gttgaagatg
     4741 taaaaaatgt tgaaaacttc agtgtacaga gtgaatcaat tcttaaatat ttaaaagggg
     4801 atgttgtaaa ttctaatgat agtagaggat gggttttggt ttcggttgaa ggaatacctt
     4861 taggttgggg aaaagaatct tctggtgtaa ttaagaatca ttatcctaaa ggtcttagaa
     4921 aagtatttta aactattaga aaaaagaagt ataatattta tattgtaggt ttatggtaga
     4981 ttattttgct gtagattgac ttaatattta acacagagga gacgatttta gtgggtgaag
     5041 cagttaaaaa agaagttgta gaatggataa aagtgattgt catagctctt gttttggcat
     5101 ttgcaataac tcgttttata gtgccaacaa tagtcaaagg agaatcaatg tatcctacat
     5161 tagttgaacg tgattatttg atagttaaca gaattgcgta caaggtagga gagccaaaat
     5221 acaaagatat aatagtattc aaaaccgact taacagagga aaatggaaag aaaaaagatt
     5281 tagtaaaaag agttatcggg gttcctggtg accatgtaaa aatacaagac tccaaggtat
     5341 atgtaaatga taagttgtta gatgagactt cctatataca taataatcgt actgatggag
     5401 atattgatat cgtagttcca gaaggaaaat tatttgcaat gggagataat agagaaaaaa
     5461 gtttagatag tagatacgat gaggttggat tggtcgacga gcataccatt ttaggaaagg
     5521 ttctagtcag attgtatcca ttttctaaga taggaactat tgactaaaca tataaaattt
     5581 ggagcaatcg ctgattagct gaaatcacca gaccatacac aatagttgtc tatataaaaa
     5641 agacaacacc ttatttagta gacttatcta aaagatagtg tttaagagac attatcaata
     5701 aagataatat aactataaag gagaatttgt gaatgaatga aactattaaa gaagagattg
     5761 tagagtggat aaaaataatt attactgcac ttttttttgc atttattata actcgtttta
     5821 taaaaccaac attagtaaat ggagaatcaa tgtacccaac acttaaatca catgattatt
     5881 tggtagcaaa caggatgaca tataagttat cagaaccaaa atgtggagat ataatgatat
     5941 ttaagactga tttattacaa gagaatggaa ggaaaaaaga gcttgtaaaa agggttatag
     6001 gtgttcctgg tgaccatcta aaaattaagg attctaaggt ttatataaat ggtaagttat
     6061 taaatgaagt ttcatatata catgataatt atactgaagg cgatattgat atggtgattc
     6121 ctaagggaaa agtatttgcg atgggagaca atagagaagt tagtttagac agtagatata
     6181 aagaagtggg attagtagat gaagaaaata ttaaaggaaa agttatttta agagtatttc
     6241 cttttacaga tataggtatt tttgagtagg tgatttgtat ggcagttggt atagcgtcct
     6301 tattgtttaa tattgaggag gctttaaaca tttgtgagag tataaagcaa ataactcatt
     6361 tagagattgg aattgacaat atatctgaat gtagtgagtt atgtaaatat aaagagagaa
     6421 tttctaagtt aggattatct atagggatac atttgcctat ggaattaaat acttgcgaaa
     6481 acatagagta tatacgaaat tcatggataa attttattga gaagatagaa tttgaactaa
     6541 aaggatttga tttaaggtat tttaaccttc atttgggata tgttatgaca aatagagtta
     6601 gaaagaatag agacaaatat ttaggaaata gtgtggattt tttagataaa ttaaatacaa
     6661 attcatatgt atgtatagag aatacttatt caaaaggtgg ggatttttca aatattggaa
     6721 atatatctta tgattttgaa tatatattta agaggattaa aaattctaag atttgttttt
     6781 gttacgatac tggacactgt ttaattgatg aggatgctta tgtaaagaac ttaaaggata
     6841 aaataagact gatacactta agtgataatg atggtatcaa tgatacacat gttggtatag
     6901 gaagaggaat tttatctgaa gaggggatta aagaggtctt aacattagat gcagaatatt
     6961 tagtattaga aataaattac gaagacattg aagatactat aagtaaattg aataatattg
     7021 taggagaggg ttaaatacct ctctttatct tgttgatatg cctcattaat taaaatttat
     7081 attcatcaaa aggaaggaga tgttgaagtg aaaaaaataa acttaaaaat agaaggaaaa
     7141 gataaggaat attcattaga agaaaattcc cctggaatca gattgggaga tatagcaaaa
     7201 gaattttgtg atgagcataa gggttatata acacttgcag ttgtagacaa taaactaaaa
     7261 gagctaaatt gtagagttaa gaaggattgt gagataaatt ttttagatac tactaatgaa
     7321 gatggagaga gagtttactt tagagtcatg tcatttatat ttgtaatggc atgtagagaa
     7381 atcttttggg atagcagagt tacaatagaa cattcactat cagatgggct atattgtgaa
     7441 gttcatatag atagaaagct taaagaagca gatgttgaaa atataaaaaa caagatgaaa
     7501 gagatagtaa acaacgatta tgttatagaa aaaattgaag ttacaagaaa tgaagctatt
     7561 tctatctttg aaaataatga aatgtatgaa aaggcagagc ttttgaaata caaagagtat
     7621 gatagtgcta aagtatataa gtgtagaaac tatatagacc atttttatgg ttatatgttg
     7681 ccatcaactg gttatataaa atcatttgat attaagcttt ataatggagg cgttataatt
     7741 ttaggaccta gtgaagaaga taagactctt cctatgaaat ttgtacctca acctaagcta
     7801 tcaagtgtat attatgaagc agaagaatgg tcaagactta tgggaattga caaggtagta
     7861 tctcttaata aaataataga aaacaatgaa tatggagata taataaggac atttgaagca
     7921 ttgcatgaaa agaagttatc ccaaatagcg gatatgataa aggatggcaa taagagagta
     7981 gttttaatag cagccccatc ttcatctgga aaaacaagtt ttgctcacag attatcaata
     8041 catcttagag taaataattt aaatcctatt tcaatttctt tagatgatta ttttatagat
     8101 agaaaacata ctcctttaga tgaatatgga aattatgatt ttgaatcaat ttatgcaata
     8161 gatttagaga agtttaactt agacttaaag aaacttttag ctggtgaaga aattgatgat
     8221 ataagattca attttaaaga aggtaagaga gaatacactg gtaaaaagat aaagatagat
     8281 tcaaatcagc caattatatt agaaggtata catgggctaa atcctatttt aacatcatct
     8341 ataccagatg aagataaatt taagatatac ataagtgccc ttactcaaat aaatttggat
     8401 gaccataatc gaatccctac tgctgatttg agaatgataa gaagaattgt tagagactat
     8461 aattttagag gatatagtgc tgataatact attttacaat gggcatcagt tagaagagga
     8521 gaaaagaaga atatattccc gtatcaagag gaggcagatg ctatatttaa ctctgcttgt
     8581 gtatatgaat tggcagtttt aaaacgattt gcgaaacctt tgttggaaga aataaaggaa
     8641 gataatcctg cacatattga agctactaga ttactaaagt ttttgcagta ttttgttgaa
     8701 ttggacgata cttctgacat accaggcatt tcaattctta gggaatttat tggaggaagt
     8761 aaaatagttg attaatgtgt gtattataga ttgttttatg aagattaaat ggcatagcaa
     8821 gtagtgtgat tggtttatgt taagtatatt aagtgtaaag tggagaatta aattgataca
     8881 gattttaaag tttgagttga tatataaaaa ggcttgtttt atacttttgt atgaagcaag
     8941 ctttttattt taaattttac ttttttgttt aatattttgt tagtttatgt gattattttt
     9001 taaaagagta aaagagtaaa agagtaaaag agtaaaagag taaaagagta aaagagtaaa
     9061 agagtaaaag agtaaaaggt gttgggttag aaatttttgg tgttataaaa atttaaatta
     9121 ctggattatt agattgctgg attgctaaat tactaggttg ttaaattatt gaattattag
     9181 gttgttgaat tactaaatta ctaggttgtt aagttactgg attatttaga tagttagatt
     9241 actaggttgt taaattattg aattattagg ttgttgaatt actaaattac taggttgtta
     9301 agttactgga ttatttagat agttagatta ctaggttgtt aaattattga attattagat
     9361 tgttgaatta ctaaattact aggttgttaa gttactggat tattagatag ttagattact
     9421 aggttgttaa attattgaat tattagattg ctaaattatt aggttgttaa attactggat
     9481 tattagatta ctaaattgct aggttgttaa attattgaat tactaaatta ttaagctctt
     9541 taaactattt aaattgtttg aaaaatgaat tgattcttgt agaaaataat tttaaagtat
     9601 aatttttttt aacattgttt tattatagta taaacttgtg ctaaaataga atatataaca
     9661 taatataaga ggtgcatatg aatacgttag atgagacatt attaaaagaa attataagtt
     9721 ctaataagaa gtatactaat tatggacaag tcgctagtta cataccagaa ttaaaaaacg
     9781 ctagaagaaa tgatttagga atttgtatca tagatagcga aaataatctt tatagtgctg
     9841 gaaactgtag cacaaagttt actatacaaa gtatttcaaa accaattgtg cttgctatgg
     9901 cacttatgga taatgattgg gaagacgttt tttcaaacgt tggaatggag ccaagtgggg
     9961 acccatttaa ttcaataatg aaacttgaaa ttaatgacac aaaaaaaccc tgtaatccaa
    10021 tgataaatgc aggggctata gtaaccactt cccttataaa tgggagttgt ttagaagaaa
    10081 aagaagaaag aatgcttagt ttctttagaa agttagcaaa aaatgataat ataggaataa
    10141 actatgatgt ctataagtct gaaaaaatga ctggagatag aaacagagct atggcttact
    10201 tattgaaaag tgatggattt atcagaggga atgtagaaga tgttctagac ctttatttta
    10261 aacaatgctc aattgagata gattctgtag atttagcgag aattggaata aatcttgcaa
    10321 attatggagt agatatagaa aatggtgagc atttaatgag tgaaatggtt tctaggattg
    10381 tcaagacatt tatgatgact tgtggaatgt atgatgcttc tggggaattt gctattaaag
    10441 ttggcattcc tgcaaaatct ggagttgggg gtggtataat ggcttctgtg ccgggacgca
    10501 tggggattgg tgtttatgga cctgcgcttg acaaaaaagg taacagcgtc gcaggagtta
    10561 aagttttaga ggagttgtca aataaactca aattaaatat tttttaaaat attaagaaag
    10621 gatttttttg acaacaacat ataatttaat atataattaa attgtaaaga aatatgaatt
    10681 aaataaattt tttaggaggg gtcaatgaaa gaggtattgg tattacgaga tttggagtgc
    10741 ataaaggcta ttgcgcatcc acgtagaata gatattctaa aagcatttga caaatcgcca
    10801 ttgtcagcaa aacaattatc tcaattattg gaagaacctc atgcaaaaat aaactaccat
    10861 ataaaaatgt tatacaaagt tggtatttta gaattagttg aggaaaaaat aaagtcgggg
    10921 attgtggaaa agtactatta tccaagtgca aaaaatgtgg ttatagggaa taggatactt
    10981 aatttttctt tagacaatgg ggaagaaaaa gaagaattgt acatatcaaa atttgaaaat
    11041 atgagtgaag ttttttataa ggcagcagag gaagatgttt tagaaaatga aaatatagtt
    11101 gattatcatg atatttctct tactcatgat gaattagttg aacttagtga cactatgaag
    11161 tcaaagatag atgaaatttt aaataaaaga caacacaatg ttgaaggttc taagtatgat
    11221 atagctatgg ttatagttcc tactcttgag gaggaatgtc ctagttagaa aattaattat
    11281 ggattaatta aagatataat attagagatt gaacatcaaa atttacttaa taatcaaaaa
    11341 atagtttttg gtatgggtaa aacaatgatt tttaatctct atttttttgt tttcttatac
    11401 ctattgtatt tgtaaataat gtgtatagtg taagatgtat acactatcta agaagtgctt
    11461 agataatata caaagtatgt aagattataa tatttgaaat tgattaaaat gggtataatt
    11521 aaagtgtaaa tattaaaatt aaaaattaat ataaattaaa tcaatgctag aaatatgtta
    11581 aaagaggaat gagattagtt gggatagaac atcccttaga gcttatgaat ttttagtgaa
    11641 aaagtactat caaataggaa tctccatctt catatgttgg ctaaatgtag ttaaggtgga
    11701 gtagttcaaa attaaaattg agtacaagtc gtagtacaaa taaaaggaga ttaatatgat
    11761 taaattagga acacatcttt caatagcaaa aggatttgct aatgcggctg agacagctgt
    11821 atatattggt gcaaatacat ttcaattttt tagtagaaat ccaagaggag gaaatgctaa
    11881 agaatttgat gaaaaagata taattaaatt tcaagaaatt agaaaagaaa ataattttgc
    11941 accactgctt gcacatgcac catatactat gaatctgggt ggtacaaagg atgatgtata
    12001 cgaatttgca acaagggtga tagatgagga tataagaagg atggactcat taggaattga
    12061 atacatgtgt tttcatcctg gaagtcatgt aggtggtggt gtagattttg gtatagatag
    12121 aatagtaaaa ggattgaaca atgccataaa gggtgatgaa aatataacta tacttcttga
    12181 aactatgtcg ggaaagggaa ctgaaatagg ttttaaattt gagcaattaa aaagtataat
    12241 agacaaaatt gagcataaag aaaaaatagg tgtgtgtctt gatacatgtc atattttttc
    12301 agctggttat gatatagtga atgatttaga tggggttttg gaagaatttg ataaggttat
    12361 aggcatagaa agattgaaaa ctgtccatct aaatgatagt atgatgccat ttggagacaa
    12421 aaaagacaga catgctccta taggagaagg aaagatagga ttaaaagcat taattgattt
    12481 tatggaacat cctagtctaa aacatttacc atttttctta gaaactcctt ttgatgatga
    12541 aggtcacaag agagagctta aaatgataaa agaaatacta tctagtaaat aaacctttat
    12601 taaaaatatg tgaaatactc cgccctcaac ataattaggg tggagatata atcatgaaat
    12661 gtgataattt aaattaatgg ataggaataa caaaaattgt atacaaatta actgggtata
    12721 aagtatgatt atattatgaa tagactgata taaaatataa ttatattatg aatagtatgt
    12781 aaatatattg caaagattct cataatttgt tgtataatta aagatgacat atttatatta
    12841 tataaaaaat tattaaaagt taggtgggga aagatatgag aaatttaggc aatactaaca
    12901 tgaaaataaa gagagttggc tttgggggca ttccaataca aaggattact caagatgata
    12961 ctaacttagt tataaatgag ttagaaaaac aaggaataaa ctttattgac agtgcaagag
    13021 ggtatacaat aagtgaggaa gcaatcggaa ttgccattga aggaaaaaga gataaatttt
    13081 tcttagctac taaaagtatg tccagagatt atgattcaat gaagagagat gttgaaataa
    13141 gtttaaataa ttttaaaact gattttatag atttatatca attccataat gttaaagaag
    13201 aggagtatga taatcttttt aaagataaaa tggcttatag tgccctttta gaggcaaagg
    13261 agcaaggtaa gataaaacat attggtataa ctagtcacaa tttaaatact atagaaaaag
    13321 ctatagaaga tggaaaattt gacactatac aattccctta caatatagtt gaaggacaag
    13381 cagatgaagt gtttaaaaaa gctcatgaaa aaggaattgg gataatagta atgaaacctt
    13441 tagctggagg tgctttagac aatgcaacac tggctattaa atatatacta tctaaagagt
    13501 acatagatgt agttatacca ggtatggaga gtgttgaaca ggttagacaa aatgtcgctg
    13561 tacttgaaaa tcttgtgcta gatgaaaaag ataataagga aattgaagaa ataagaaatt
    13621 ctttaggtaa aaaattctgt agaagatgcg aatattgtat gccttgtgct gtaggaataa
    13681 atataccatt gagtttttta tgtgaaggtt attatactag atatggatta aaagagtggg
    13741 ctaaagaaaa atatgaggtt atggatgtta aacctactga gtgtattgac tgtgggcttt
    13801 gcgagagtag atgtccatat gaacttccta taagagaaat gcttaagact gttgttgaaa
    13861 agctaggata gattttattt attgaaatcg gtgtattaaa tttactccga tttcttttta
    13921 ttagatgtgg tcttatatac aaatattaaa tttacatagt tatagctatt atataaattt
    13981 aatatttgtt taatacttat taaatattta cttaatgctt tttaaaaaca tttgtttgag
    14041 tatagacata acacaattat tattgttgta ttagtatagt ttcaaatact ggagtatcaa
    14101 tataatgtcg aataacacat aaaatcttta tttttcaaaa atattatagg atatatcgta
    14161 tttagatact ggataaagtt caatttcaac cctagggtta tctttatcta taaaatcaaa
    14221 taaaagtact ggcttaagtt gtttatcatt ttttattatt ccactttttt caataccatc
    14281 acaaatactt tttggataat tatgtaaatc ccccattctc ttatttggga agaataattt
    14341 caagactgtt attagatttt cttcaacagt ttccccttga tactgttggt ttataaaacc
    14401 tgcaatcatg ttttcgtatg caagatactt agaatatttt ccctttgaag gcatccatgc
    14461 ttgaccattt atgttatgaa gcttaaaatt agatttacta ataggtctac ctggaattgt
    14521 tattttaatc aaatttttca ccatccttat acagtattta ttataatctg tatatgattt
    14581 aaaagcaaat tgttatttaa agtgttttac agagcttttt tgtaaaattt tccactttag
    14641 atgtagtaat ataagataag tattttgctt acaaatttta aaatttgata tatgatggac
    14701 atattcatat tagactatta taagaccttt ataatattaa taagtatagt ttagtaaaga
    14761 gagtaaaaag aaatccatat aagtcaagta aagacttaat aaatggcaat gtaaatggga
    14821 tattaattat aagaaaaaat caatcttttt gcttaactat agaaaaaatg tcaaaatata
    14881 actaatgata tttgaagttt tagagtttat attaaaaggt aagaaggtta agtgggtaaa
    14941 aaaggttgaa tagattaaaa aggctaagta tctaaaagag ttaagtaggt aaaaaagtta
    15001 aataagtaaa tgaaaaaggc taagtatcta aaagagttag taggtaaaaa agttaaataa
    15061 gtaaatgaaa aaggctaagt atataaagga gttagtagat aaaaaaatta agtatctaaa
    15121 agcgttagta gataaaaaaa ttaaataaat aaaaaagact aagtattcaa aagagttagt
    15181 aggtaaaata attaaataga taaaaagact aattatttaa aggagttaag tagataaaaa
    15241 agttaaataa gtaaatgaaa aagacgaagt atctaaaaga gttagtaaat aaaaaagatg
    15301 aagtatctaa aagagttagt aaataaaaaa gatgaagtat ctaaaagagt tagtaggtaa
    15361 aaaactaaat aggtaaaaag atgaagtatc taaaagagtt agtaggtaaa aaattaaata
    15421 ggtaaaaaga cgaagtacct aaaagagtta gtaggtaaaa aaattaaata gataaaaaga
    15481 cgaagtatct aaaagagtta agcaggtaag aaaattgaat agctaaaaag attaagtatt
    15541 taaaagagtt agtagctaga aaaggttaaa aagactaaaa aaattaaata aatttaaaaa
    15601 gtcaattaga ttaaaaagga ataattttat ggataataag gaattaaaag cattttgtaa
    15661 tttaatagga ttaaactgtg taggagtagc aggggtagat aagtatgata atttagaaaa
    15721 gatacttaag gacagacaac aaaaaggtta tttaactggt atggaagaac caataattga
    15781 gaacagaatt aacccaagac atataatgaa ggatgctaac tctataatag tctgtgcatt
    15841 tccatatcat ataaatagac aagaaaagaa taaaaattca aatttatcaa aatattgtca
    15901 tggaaaggat tatcacattg tagtaaagga ctttttacaa caaatttgtg attatatttc
    15961 taaaacagta acagatttta aatacaagtt atttgctgat aatggaccat tagttgacag
    16021 gtatttagct tatttatcag gaataggata ttttggaata aataataata tcataactga
    16081 tgaatatggt tcttacgtat ttatagggta tatagtaaat aattataaat ttgaagaaga
    16141 taaaccacta gaaaaaagtt gttttaaatg tggtaagtgt gtaaaatatt gtccgggaaa
    16201 tgctatattg ggaaattatg atatgaaccc caaaaaatgt ttatcatata taactcaaaa
    16261 aaaaggagat ttgtcagaga aagaaaaagt tgttttaaag aatggcaaaa aggtatttgg
    16321 atgcgatatt tgtcaagaag tatgtccaca taatgttgaa ataccaacaa ctcatatttt
    16381 ggaatttaaa gaaaatataa tagactattt ggattatgat gagatacaaa atatttcaaa
    16441 taaagaattt aaaaggagat atggagatag agcttttagc tggagaggga gaaatataat
    16501 aaagagaaat atggaaataa ttttagataa gtatgatgac taataataag agtctgtttc
    16561 atatacttta atgtgtattt actttaacac ttgttgtgta aaagtcatat tatatcatta
    16621 aagttaaata tggggaggtg ggggaatatt gaaatataat aatacatctg aaataaatcc
    16681 actagattat atattgggtc aagaaagagc tgtagaagct atggaattag ggttgaaaat
    16741 aaataatcca gcgtacaaca tatatatagc tggtgaacct ggaactggta aaagtactta
    16801 tgccttaaag gttttaaatg agtatgcatc caaaaaaaat acgcataaag attggtgtta
    16861 tatatataat tttgaaaacc ctagagagcc tattatagtt gaattagaaa aggggtttgg
    16921 aagagaactt aaaaaagata tggagaaatt aattgaaagt cttttagaag attttaaaaa
    16981 tgcgtttgaa agtgaaaatt ttgaaataga aaaaaataaa cttctggatg aatatgaaat
    17041 agaaaaagat atgcttttga agcaaattaa gaaatatgga gaagaaaaag gatttaaatt
    17101 aaaacagagt aaaatgggaa tagtttttat ccctttgaaa gaagaggaag atgaaagtga
    17161 tgagtctgat gaagagtttt acaaagctaa aagagaacta gaaaatatgg cgatacaggt
    17221 cgtatataaa attagaaact tagaagaaat agctgaaaaa gcagtgttag agcttgaaga
    17281 agagatagct aaacttgtag tagaacctca tatcaagaga ttgtgtgaaa aatatgaaaa
    17341 ttatgataag attcaaactt atctggaaaa tataaagaaa gatataatag aatatatgta
    17401 tttattctat ttagatgaag aggagttaaa agataagtat gataaagaac attttattaa
    17461 atataaaatt aacctatttg tagacaatgg aagctcaaag aataaagaat cagcacctgt
    17521 tgtagtagag ataaacccaa gtccagcaaa tctatttgga aaggcagagt atgattatgc
    17581 aaatggaaat ataaagactg atttcacaaa actattatca ggagcatttc atagggctaa
    17641 tggtggttat ttagtacttt atgcagacca attactaaaa tatacaatgt cttgggaaat
    17701 tcttaaaaag actttgcaga ctaaaaaagt aatattggaa acacaaacag caattaaacc
    17761 agaaaatatg ccattggatg ttaaattagt actgattgga agccattata tatatgatat
    17821 tttatataga tatgatgaag attttgaaaa atattttaaa gtatttgtag actttgatag
    17881 tgaaatggat aaaaatgaag ataatgaaga aggaatagca agatttatag cataccaatg
    17941 tgataagaat aatttaaggc attttactaa atcagcagtt gaagaggtta ttaaatttag
    18001 cactagatta tctggtgatt tagaaaaact atcaactaag tttaataaaa taatggaagt
    18061 tgtaatagaa ggaagtgctt atgcagagtt tagaaattcg gagtatacag agcagtgtga
    18121 tgttaaaaaa gcaataagtg aaaagagaaa aagaatcaat agagtggaaa cacatatgga
    18181 tgaatcaatt gaaaatggat ttactctaat agaaacagag ggaagaaaag taggcgtgat
    18241 aaatggtctg tcagtcttaa gtacaggaga atactctttt ggtagagctt caagaattac
    18301 agcgaccact agcccaggaa gtaaaggcat agtaaatata gaaagagaag taaatatgag
    18361 tggctctata cataacaaag gagtacttat attaggtggc tatctttctg agaattttgc
    18421 acaggattta ctattgtcac taaatgcata tgtttgtttt gaacaaaatt atggtggaat
    18481 agatggagat agtgcatctt ctgcagaatt atatgtacta ttatcatctc ttagtggagt
    18541 atcaattaaa caaaatattg ctgttacagg ttctataaat caaaagggtg atatacaagt
    18601 agttggtggt ataagtgaaa agatagaagg attttattct atatgtaaaa ctaaagggtt
    18661 aaatggtgag caaggtgtca taattcctag aaaaaatcaa agaaatctcg ttttatcaga
    18721 tgaagttaat gatgcagtgc gagatggaaa atttaagata tatactgttg aaagagtaga
    18781 agaggctata gagatattga cagatgttaa atttgaagaa ataaagaaat tggtaaaaga
    18841 aaaattaata tctttcagca agatacaaac tgtgtcaaaa gaataagttt attatagaat
    18901 ttaatgggta tttatgtata ataaaaagca agaactttaa taggtttttg ctttttttgt
    18961 aaatatatat aaattaaatt cttattttgt atgttttata tattgatgtt tattttttgt
    19021 tgatatgatt aaactattta taaatagcgt tttataaatt agtattttaa agggggataa
    19081 ttatgaaaaa tgtaaatcta aaagagataa atgaaaaaga tgtaattgtg gaagaagata
    19141 taaatctaaa aggaatggat aagaaagatg taattgagaa ggaagaagta aataaaaaaa
    19201 gtatagataa gaaagatata attgagaaag aagagataga taaaaaaaat gtaaagaagg
    19261 tcgaggttca aaaaggaata gataaaatga ttggtaaaaa agatgagata attgatgaga
    19321 aagatataga gaattttatg gatattgaag aagataaaaa aagtatcaaa gtaagtaaaa
    19381 aaagtactaa aaaaggtgaa acggagaaaa aaacaaagaa gagtagttct aataaggcta
    19441 cacaaaaaac aagtaaagaa actaaaagta agtctaaaat taaaaatgag tcagcaaatg
    19501 aaaaagacgt aaataagatt ttagacgagt tagaaaaatt gtatccagat gctaaatgtg
    19561 agttaaatta tgggacagcc tttgaacttt taatagcaac tattttatca gcacaatgta
    19621 ctgatgtaag agtgaataaa gttacttcag agttgtttaa aaagtacaac acagctagag
    19681 actttgctaa tttgagcatt gaagaaatta gtaaagagat aaagagttgt ggtctttaca
    19741 aaagcaagtc tcaaaaaata aaggatacat ctgaacagct atgtgaatta tatgatggtg
    19801 aagtacctga tagcttagaa aagcttataa aattacctgg tgttggaaga aaaacggcag
    19861 gggttgtact tagtaacgct tttaatcatc cagcaatagc tgtagatact catgtattta
    19921 gagttagcaa tagaatagga atagtggacg agccaaatcc tcaaaaaaca gaatttgcac
    19981 ttatggaaac tataccaaaa gaaagatggt cacactcaca tcatgtatta atttttcatg
    20041 gaagaagaat gtgtaaagct agaaatccag aatgtgcaag ttgcccaata aaagaagatt
    20101 gtaattatta taaagaactt aatgaaacga aataactttt agaaagtaag ttgtacaaga
    20161 gggattttct gatataataa tacttgtgaa aatgttagat aaaaaactat tatatacatg
    20221 aaataaaaat tattattaac attattttat ataatagtat aatattattg ttattctgtt
    20281 tataaaataa aatttgataa ataaaagcaa tacttaggga ggattaaaat gtcattaaat
    20341 atagtattag tagaaccaga aatacctcaa aatacaggaa atataataag aacctgtgca
    20401 gcaacaggtt caactttaca tttagtaaaa ccactgggtt tttcattgga tgataaacac
    20461 ctaaaaagat gtgggcttga ctattgggat atagctgata tacaatatta cgatagcttt
    20521 gaagaattac aagaaaagta tccaaatagt aaatactttt tttctacaac aaaggctaaa
    20581 cagtcacatt cagatgtgaa atatgaagaa aattgtttta tagtatttgg gaaagaaaca
    20641 aagggattac cagaaccttt gttgaaagca aatatggata cttgtattag agtgcctatg
    20701 ttggatgttg aaaaagctag gtcattaaat ttatcaaatt cagttgctat tgtagtgtac
    20761 gaggctttaa gacaaatagg atacccaaat atgaggtagt tttaacaagc ctaaatgaga
    20821 aaggagcata cttaatgaaa aatctaaaga taatctgtga cagtttatcg gacgtgccaa
    20881 aagatttgtt agataaatat gatatagata tagtttcatt aacagttata ctggaggaaa
    20941 gagaatacaa ggatagaatt gatatatctg gagatgaatt ttataaaagg cttagagaag
    21001 aaaatgtata tccaaaaact tctcaagcta cttatgccca atttaaggaa atttttgaga
    21061 aatatacaaa tgaggataga gagatacttt atatagcagg gtctgccaca gctacaggta
    21121 cgtatcaaag tgctgtaatg gcaaagaatg atgtagatgg taaaatatat acatatgact
    21181 ctaacttgct ttgtatggga actggtttac ttgtaataaa agcaggagaa cttgcaagtg
    21241 aaggaaagtc tgttgctgaa atattgcctg ttttggatga attaaaagag aaggcttttg
    21301 ttatattttc agtagataca ttggaatatt tacaaaaggg aggtagaata tcatctacta
    21361 aggcagcaat aggaagtata ttaaatataa aaccgattct tgaaataaga gatggattag
    21421 tttcgcaaat atctcaagta agaggaaaga agaatgtaat ttctaagatg atggaattga
    21481 taaaatcaaa ttgtggtgat gatttatcag accaaattgt gtatatagga tatagtgatg
    21541 attttaagga aaaggaacaa ttatctaagg ttatgcaaga tgaattaaga cctaaagaaa
    21601 ttagattttt ccaaattggt gtgtgtatag gtgcacatgc tggtcctggt gttactggta
    21661 tcatatgctt aaaaaataaa taatatattt ttggatgaca ttatttattt ttttattaaa
    21721 ttaggataga atattaatta ttgagatgtt aaattggatt tattttggat gaaattaagt
    21781 gttgatatat tagatttagt ttgtagggaa gtgtgtaaat agataagaat ctattgcaca
    21841 cttttttata gtaagattta ttaaaaaaat ttcaaaatgt acttgtaaat tgtatataaa
    21901 aaaatt
//
LOCUS       DAMKNB010000061        21697 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.063, whole genome shotgun sequence.
ACCESSION   DAMKNB010000061 DAMKNB010000000
VERSION     DAMKNB010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 21697)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21697)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21697
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.063"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            68..1375
                     /locus_tag="PC494_002557"
     CDS             68..1375
                     /locus_tag="PC494_002557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3913048.1"
                     /translation="MKEIADAITSEYLSYGINEDISIYEGRFCIYLDKKYRCNGKIYY
                     KMTPPISISFKADIGCVEEIDNEDDNLALDYDNAILEVHGYKIISITINTLSEFSVEG
                     YINDDCIKSKNSYVEYVDFNIINLDKIPGKLIKYNDKVYAGRIEFDINDYVVTIDKRY
                     DYRKELKSELKSKSGAIITHIGRIRRKDGRIFRTNNTINLLDRISTALSFMCGRYVGF
                     CLAKGYRSGNEVYRIWNENQISPFRYVPTWSDTLSNYYNMEKYISLMCKKLEDFYYGS
                     AIKSVVDWYIESLGSATMENNIISVQIALETLSYVILVEQNKILTDEVFDCNLASKNI
                     RLLLDTCKIPYGKHELNIFDNIIKNKFDDGVDLVIYLRNSIVHPSRKTHRAVLEVEDI
                     WNIISIGTRYIELVLLFILGYRGEYSNRLVERCYGEVEVVPWN"
     misc_binding    1461..1723
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            1849..2652
                     /locus_tag="PC494_002558"
     CDS             1849..2652
                     /locus_tag="PC494_002558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HDF3913049.1"
                     /translation="MKNILKKVGIFTIMLGLLGGVVGCSKPDNEKDKDASKESKKEVV
                     VGFDNTFVPMGFLDEKGDTVGFDVDLAKETFKRLGMEVKFQPIDWSMKETELNDSKTV
                     DVLWNGYSITDERKKIVSYTEPYLQNKQIIVTLSDSKINSKADLKDKEVGTQQGSTAL
                     DAVEKDKDFMNSLKGGAPVLYDTYDKALRDLEIGRTSAVVGDEVLIRYYMGQKGEDKY
                     KVLKDDFGLEDYVVATSKENPELCEKINETLKEMKKDGTFDKIYDKWFK"
     gene            2690..3301
                     /locus_tag="PC494_002559"
     CDS             2690..3301
                     /locus_tag="PC494_002559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HDF3913050.1"
                     /translation="MLQGLEIVIAMFCITLIVSIPLGIGVAFLRLSKNKLVSGITQCY
                     ILIMRGTPLLLQMIVIFYGLPLLGIVFDRFTAGVVAFFLNYAAYFAEIFRGGIQSIDR
                     GQYEASKVLGFDKFTMYKRVIFPQVFKRILAPISNEVITLVKDTSLVYILGLNDILRI
                     SQIAMNREASLLPLFEAGAIYLIFVAILTKGFELLEKKYSYYR"
     gene            3333..4004
                     /locus_tag="PC494_002560"
     CDS             3333..4004
                     /locus_tag="PC494_002560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HDF3913051.1"
                     /translation="MLKIKNLNKSFKKNRVLKDISFELEEGQIGVLLGKSGAGKTTIL
                     RCINGLEEFDSGEIIIDNEVIKNKRDMAKIRGKIGMVFQNFNLFPHMTVLENIIESPV
                     NVFKVPRKEAEERARELLRLVDLEDKLNSYPFELSGGQQQRVAIARSCALMPKVLCFD
                     EPTSALDIDTIQRVVNIMNRLKDKGMTILIITHDVVFSNNVADKIISIKDGIVENVQI
                     KEKIV"
     gene            4302..4664
                     /locus_tag="PC494_002561"
     CDS             4302..4664
                     /locus_tag="PC494_002561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HDF3913052.1"
                     /translation="MIKLYGYTKCSTVKKAKNWLKENNLEFEDIDMVQNPPSKEELKS
                     IYKTSGYDIKKFFNTSGMKYRELGLKDIVKTESDDKLLEILVSDGMLIKRPLLLDGKN
                     VLLGFKEDVWKSTLLKED"
     gene            5100..5801
                     /locus_tag="PC494_002562"
     CDS             5100..5801
                     /locus_tag="PC494_002562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4253 domain-containing protein"
                     /protein_id="HDF3913053.1"
                     /translation="MSIEDLYDFECVPLNNEIDIDVLFEKMIEDGKEKEYTPIIVIDE
                     KVGLLRKNIDMITKEYGSLENYREYCLTKYNEIDVNQFFDFRKSEISELLKELIDLED
                     DFYDYKHFRPIMNIDIFHEYNKVYIAKIPTIKPYEVFAYIPIGGFNDCPRDEEHIAIA
                     KYWYEKHGIFPIAIGCDTVQYSVKNLTKDGKKFDDLCIELVFYCEDIIIQGYETLKAL
                     KDVLKRSTIVLFWWD"
     gene            6071..6889
                     /gene="larE"
                     /locus_tag="PC494_002563"
     CDS             6071..6889
                     /gene="larE"
                     /locus_tag="PC494_002563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent sacrificial sulfur transferase
                     LarE"
                     /protein_id="HDF3913054.1"
                     /translation="MEVNFVKEKEKLDKLKKMLLELGSVVVAYSGGVDSNFLLKVAKD
                     TLGENVIAVTIHAMMHSSREIEEAKQYTQNFGVKHIILNIENFDLKEFKENGVDRCYH
                     CKKYIFSKIKEVAKEHNIKYIVDGTNIDDLGDYRPGLKALSELGVISPLKDSSLKKEE
                     IRSLSKTLGLNTFNKPSFACLASRIPYGVEITDENLRIVEKSEEYLSNLGFSQFRVRM
                     HGDIARIEVGQEELGKFFENNNFNKVDTKLKIFGFKYVTLDMSGYKMGSMNLNV"
     gene            6944..8092
                     /locus_tag="PC494_002564"
     CDS             6944..8092
                     /locus_tag="PC494_002564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HDF3913055.1"
                     /translation="MKNYTLISPCFFGMEKMLAREITNLGYEIIKTEDGRITYKTDEF
                     GIAKSNMWLRCAERVHLKIAEFEAKSFDELFENTKRINWSRYIPYGAQFPISKASSIK
                     SKLYSTPDVQAIVKKAIVESLKKSYLEDGLLKEDKEKYPIFVFIHKDKVTISIDTTGD
                     ALHKRGYREKANKAPIRETLAAGLIYLTPWKAGRVLVDPMCGSGTILIEAAMIGINMA
                     PGLNREFISEKWRTLDKKIWWDVRKDAFNKIDNESKFKIYGYDIDEESIDIARENAEI
                     AGVDEYIEFNVGDATQFKSEDEFGFIITNPPYGERLEDKDSVKQLYKELGYAFRKLKN
                     WSYYLITSYEDFEYEFGQKADKKRKLYNGMLKTNFFQYPGPKPPRNNK"
     gene            8228..9616
                     /locus_tag="PC494_002565"
     CDS             8228..9616
                     /locus_tag="PC494_002565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HDF3913056.1"
                     /translation="MKVLKLITVVALMMLFVTGCNIKTESPEQLAKIPDYDDTKKVLY
                     DGIDQLLKPDSSMILPSNTKEVGKINKVDLNSDGIDELVVFEQKEDLSNNVSQVGFVT
                     LSYNGEKYVLGDHFLENGESIEYANFYDLDSDGYKEVILLVKSKDKTNMHIYKVVDNE
                     ITKIYDLDASWLQNKEDFNDMKVKIGYIDGDDKLDILMLHLNNKTNEMFASVANFDGK
                     MKIKDSVKFENVKNLSELYITLGNVASSVGNSSAAIKGIVLDIPILKDNNYITQILYM
                     KDGKINKAFSDYDKTITKSYYIPVDDIDKDKIIEIPIVAGSTGNNKNTYSSKSSATIS
                     WYRWNGKEGADSSLIFTSQIYYNYKYNFKLFIPNNLFDKILVEQEFVGEKAVFKFYYF
                     DYSDRKNLFNIVVESKNKLEDRKNTGTQNSIVLQESDEYTFLLVVNNANEMDKLDMTI
                     DALKEYFSLIYG"
     gene            9645..10343
                     /locus_tag="PC494_002566"
     CDS             9645..10343
                     /locus_tag="PC494_002566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF3913057.1"
                     /translation="MKEKILILEDEIGIRSFVSINLKREGYEIVEAGTGREAIEKMTT
                     EKDITIALLDVMLPDISGIEVCKFIRENFDQVGIIMLTAKAQEDDKIEGFISGADDYI
                     IKPFSIKELLVRVSALLRRVAKDDSSVKSSEIVSPPFILDIDKRKLFKNGKEIELTPT
                     EFSIVKYLISNAKQSLSRDQILDEVWGTNYLYDFKIVDVNIRRIRNKIEDDPSKPKYI
                     QTIWGYGYCFRKEE"
     gene            10346..11779
                     /locus_tag="PC494_002567"
     CDS             10346..11779
                     /locus_tag="PC494_002567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF3913058.1"
                     /translation="MLHFEGLRKKVIKNYFIIIIIMVTLFEGLFMFYIQNYYYDSVKQ
                     LLESEIKYADEYNAITMETTSFEKKVKNIFDKQPLTKNSEFGISIIDKDKNIILDQYG
                     FKSKEKANYEDVNNALKDIKTKNLTPYTYRIPDTGEHVMSISLPLKVNNIIEGVVRYT
                     VSLDAIDNAILKQATWLILAGIFILIIAILISLKFAETLIKPLRELKKFANELAVGNY
                     NIKLEKMKIVDDEIGDLAQTFEHMAHEIDKSEKLKEEFISSVSHELRTPLTSIKGWSE
                     TLGYESITREELDLGLGIIQDETERLIKLVEELLDFSRLSSDRIKLHVDIVDVEGLIV
                     GVVNQLKVKAAEKDISLLFEFENEFIENIQGDKNRLRQVLINLIQNSFKFTSQGGYIK
                     VVASQDEEITTISVEDNGSGIEKQNLNKVLDKFFQEDYNKAGSGLGLAISNEIVKLHG
                     GRMKIESEKNVGTKITFNIKNKFAKQA"
     gene            11801..12538
                     /gene="truA"
                     /locus_tag="PC494_002568"
     CDS             11801..12538
                     /gene="truA"
                     /locus_tag="PC494_002568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011010156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HDF3913059.1"
                     /translation="MRNIKMIVAYDGSRYKGYQKLGDNNMTIQEKLENVLSKMTNETV
                     EIIGSGRTDMGAHARGQVVNFRTNCMDSLDKIQKYLYEYLPEDIVVKTVEEVDERFHS
                     RYNVKSKTYMYKIDNNKYHNPFIRKYATHVSKKLDLDRMRKASEYLVGEHDFTSFASS
                     KSKKKSNVREIYSINIKEDDNVIEIYVEGNGFLYNMVRIIVGALIDVGLKRRAPQDIK
                     YMLESKDRCQSSDTAPAKGLCLWKVTY"
     misc_binding    12649..12856
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            13109..14308
                     /locus_tag="PC494_002569"
     CDS             13109..14308
                     /locus_tag="PC494_002569"
                     /EC_number="6.3.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate synthase"
                     /protein_id="HDF3913060.1"
                     /translation="MKEKVVLAYSGGLDTSIIIPWLKENYEDIDVIAVCGNVGQEDKM
                     EDVYEKALQSGASKAYVDDISEEFVTETIFKAVKAEAKYEGKYLLGTSLARPIIAKKL
                     VEVAHKEGAKYICHGCTGKGNDQVRFEATIAALDPTIKVIAPWRIWDIKSREDAIDYA
                     EKHNIKVTATKAKIYSVDANLWHVSTEGGDIEHLENEHKKDVYKQCVDPEDACDVAEY
                     VEVYFEKGVPKKVNGEELSPVALIHKLNELGCKHGIGVIDIVENRLVGMKSRGIYETP
                     GGTILYEAHNILESATLDKDTLHFKQMVSYKYGELIYNGLWYCKLRESIDAFMEQTQD
                     NVTGTVKVKLYKGNIKPAGIFTENALYDEGISSFGNSELYDHKDAEGFINLFTLPLKI
                     RAMKAGK"
     gene            14555..15601
                     /locus_tag="PC494_002570"
     CDS             14555..15601
                     /locus_tag="PC494_002570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4872 domain-containing protein"
                     /protein_id="HDF3913061.1"
                     /translation="MRKIIEIKHHSHDYECMWNGIEDLYINKTGEYLPNDFFFLLSGF
                     GSFCYMKTNKADLKRMVALGDGRTKQMYKFLAPIVGFEYKHHEFKKYEQALKKAKSEI
                     DDGYPVILGALDMYYLPYYKKLYHKEHIPFHYILMVGYDDEGIYLYDCGRTELLHLSY
                     DKLRESMNCNSPGLSKENTICTIRMNTSKNKYNIAREAIAIKRDMFLNPPKGFLGYKG
                     FEKFIKELPQWNTELDKDDYDKILTNMVMFFGTVPTIPNAIKGIKEPDTVQFKGGFDK
                     MSRMLNSIGEEYKNNSFIQVADIFDKTAIIIEKISNIIIDYLTQTCDDTEQLPLLFSE
                     VLEHMKTGYLILDV"
     gene            15709..16872
                     /locus_tag="PC494_002571"
     CDS             15709..16872
                     /locus_tag="PC494_002571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HDF3913062.1"
                     /translation="MRTVKQVSDLTGISVRALHYYDEIGLLKPNKITDAGYRLYDDES
                     IKTLQQILFFKEIDIPLREVKEIMSSQYFDKVEALKNQKKLLILKRKRLDELIELINQ
                     TLRGEGNIDFKEFDMSEYFNVLEEFKREHRNKVIKIYGSVEKYNEYIERVKSNEEKIA
                     KMAIKQYGTIEKFAKAIKTNFSSDILNLGEKFDRYKNDCLKEKHPKLKELYRKLVEDL
                     SRNPSSTDLQEIAKAITDISKKDYEIFSMDTGDDNWYYMVQNYLVNPMWIEEVDKKYG
                     SGAGKFIGQVLKTYLRDRKPKINTLYEKLVEDLSRDCSSREVQSIVEEIDNEMKRSNE
                     FYKIDNGERYFDYMSELYLQDSNYIKVTDKNYGDGASKFIGEAFKIYFDNNNC"
     gene            complement(16961..17341)
                     /locus_tag="PC494_002572"
     CDS             complement(16961..17341)
                     /locus_tag="PC494_002572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4363 family protein"
                     /protein_id="HDF3913063.1"
                     /translation="MKSTTFVILWTILFVLFGFYVNNKLYDFTEGYKDNISVLEKSIE
                     NEDWEKAQKEADSISTSWNKEKNHWYKVLNHEYFDEIGLRFNILDKAIYTENKLKSLE
                     EVESIKTYLGNIIESVKFDVNYIF"
     gene            complement(17344..18003)
                     /locus_tag="PC494_002573"
     CDS             complement(17344..18003)
                     /locus_tag="PC494_002573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HDF3913064.1"
                     /translation="MTVVLIRSIILYITVLIALRVMGKGEIAEMNCFDLVITLLIAEV
                     ASVPMENNNIPIINGVAAISGLVIMQTLISFLSLKSRKLSSFLSGKPSVLIDKGKIVY
                     KELKKERISIDELLEQLRIQGYFNLKDVQYAILETDGNLSVVPASSYNSTPPRAFNHL
                     PIPLILDGRIINKNLDIAQKDTNWLMGILKSNHIETFKDVLICVLDENDKIFIQNKKG
                     D"
     gene            complement(18109..19083)
                     /locus_tag="PC494_002574"
     CDS             complement(18109..19083)
                     /locus_tag="PC494_002574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease domain-containing protein"
                     /protein_id="HDF3913065.1"
                     /translation="MKYKLFIDFEFNILDDNKNKPKEYNGAELISIGGVLVDNEFNTI
                     DNYYSLVKPKYNKILSNKCKNLTKLNQLDINNAPNLLYVMDDFYKWFCKFDDVTIYNW
                     GDFDITGLLTSFRVYKYTGKCLELFNMMIDIQPFISQHITYNNRILSKQISLLNMKKI
                     FSVEGDIKHNSLSDAVDLMNVCKCFFFNSPKNIDILEELYNKLPALKTPLYYIPYFED
                     ENFELKFDRTPEDIIIYLKQILTILNISKKEIYFKKRSVLVNNSKIINFKNLSSSFKL
                     IKLNEFEEYPDFILKLGDKKSFVESVIKINKSNRKSIKNLILKLSKKP"
     gene            complement(19123..19470)
                     /locus_tag="PC494_002575"
     CDS             complement(19123..19470)
                     /locus_tag="PC494_002575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3913066.1"
                     /translation="MLNLKEIREEIIKKYIGDSLISELTEELKNILITDLQSNPFKSN
                     IELSIIPANIEIFKKIENILIDSKVNLKMGWERILINYILKDLFELNYEINKSCNEPL
                     MFRVIISIDSYDA"
     gene            complement(19688..20644)
                     /locus_tag="PC494_002576"
     CDS             complement(19688..20644)
                     /locus_tag="PC494_002576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonine 3-dehydrogenase"
                     /protein_id="HDF3913067.1"
                     /translation="MKKILITGALGQIGSELTIKLRNEYGEQNVIASSRRVKEGNPVC
                     ESGIFEILDVTDKNRFFEIAKKYDVDTIIHLASLLSAVAESKPLEAWNLNMNGLINGL
                     EIAKELDCKFFTPSSIAAFGENSPKNMTPQDTLQRPNTMYGVTKVSGELLCDYYHSKF
                     GVDTRGVRFPGLISYVTPPGGGTTDYAVDIYYEALKNKRYKSYIAEGTKMDMMYMPDA
                     LQSIVDLIEAPADKLIHRNAFNITAMSFSPEEIADSIKKYIPDFVIEYDVDPVRQSIA
                     DSWPNSLDSSSAVKEWNFKFSYDLDKMTKDMLEKLSEKGIGK"
     gene            21087..21455
                     /locus_tag="PC494_002577"
     CDS             21087..21455
                     /locus_tag="PC494_002577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C-GCAxxG-C-C family protein"
                     /protein_id="HDF3913068.1"
                     /translation="MTRPSIYHSQGYTCAEALIKSYNEEHNTDIPISIGSGMGVGMNV
                     GSVCGAVNAAVVIIGYLNGRNSNLDENIARKYSRELLNRVRNKYSSEICVSLKKNKVT
                     CEEIINFTYDALNDMLKNQK"
BASE COUNT         8585 a         2215 c         3592 g         7305 t
ORIGIN      
        1 attaaattat ataaattaaa ttatataata tattgagttt tacataaaag caaaggtggg
       61 aataaaaatg aaagaaattg ctgatgctat aacatcagag tatttaagct atggtatcaa
      121 tgaagatatt agtatctatg aaggtagatt ttgcatatat ttagataaaa aatatagatg
      181 taatgggaaa atttattata aaatgacacc tccaatatct ataagtttta aagcagacat
      241 aggttgtgtt gaagagatag acaatgaaga tgacaattta gctttagatt atgataatgc
      301 tattcttgaa gttcatggat ataaaattat ttctataaca ataaatactt taagtgaatt
      361 tagtgtagaa ggttatatca atgatgactg cataaaatct aagaactcct atgttgaata
      421 tgtagatttt aatataataa acttagataa aatacctgga aaactcatta aatacaatga
      481 taaggtatac gcaggtagaa ttgaatttga tataaatgat tatgttgtaa ctatagacaa
      541 gcgatatgat tatagaaaag aattaaaatc agaattaaag tctaaatctg gagcaataat
      601 aactcatata ggtaggatta gaagaaaaga tggtagaatt tttagaacaa ataatacaat
      661 aaatctttta gataggatat caacagcttt gagttttatg tgtggaagat atgtagggtt
      721 ttgtttggcc aaagggtata gaagtggtaa tgaagtttat agaatatgga atgaaaatca
      781 aatatctcct tttagatatg taccaacatg gtcagataca ctttcaaatt attataatat
      841 ggaaaaatat ataagcctta tgtgtaaaaa gctagaagat ttttattatg gttctgctat
      901 aaagagtgtt gttgattggt acatagaatc tcttggaagt gctaccatgg aaaacaatat
      961 aatatctgta caaattgcac ttgaaacttt gtcatatgta attctagtgg aacaaaataa
     1021 gatacttaca gatgaagtat ttgactgtaa tttggcatct aaaaatataa gactcttact
     1081 tgatacatgt aagataccat atggtaaaca tgaattaaat atatttgata atataataaa
     1141 aaataaattt gatgatggag tggatttagt tatttattta agaaatagca tagttcatcc
     1201 aagtagaaag actcatagag ctgtgttaga ggttgaagat atttggaata taatttcaat
     1261 aggaacgaga tatattgaac ttgttttact ctttatttta ggttatagag gagaatattc
     1321 aaacagatta gtagaaagat gttatggtga agtggaagtt gtaccttgga actagatttt
     1381 tatatttatt ttaaaatata tattgacata tattgcctta tgctataaaa tcaatatcat
     1441 aataataatt cagaataaca ttaaatgcta agaaaagaaa tagtaaaagt agttaatctt
     1501 aaacagagag tttccgattg gtgagaggag caatagattt tactttgaac acatctttga
     1561 gcaggactct gaaagagtag aaatacttta ttaggagatt tccggaatcc ttgcacccgt
     1621 tatagtgcta gagtataata attttattgt acttaaagag gttagtgtcg tgaggcatta
     1681 atgaacagag gtggaaccac gagagttaac tcccgtcctc tagcagaagc tagaggcggg
     1741 agttttttaa tataattttt taagcgcgca gagaattata ttgcaataga tacacttttt
     1801 aaaaaataat caaaatattt taaaaattaa aaggcgaggg agaatattat gaaaaatata
     1861 ttaaaaaaag taggaatatt tacaattatg ttaggtttat taggtggagt tgtaggttgt
     1921 tcaaaaccag ataatgaaaa agataaggat gcttcaaagg aatctaaaaa agaagtagtt
     1981 gtagggtttg ataatacgtt tgtaccaatg ggatttttag atgaaaaggg agatacagta
     2041 ggatttgacg tagacttagc taaagaaaca tttaaaagac ttggaatgga agttaagttt
     2101 cagcctatag attggtcaat gaaagaaact gaattaaatg attcaaaaac tgtagatgta
     2161 ttatggaatg gatattctat aacagacgaa agaaagaaaa tagtatcata tacagaacca
     2221 tatttacaaa ataagcagat aatagttact ctaagtgact caaaaataaa ttcaaaagct
     2281 gatttaaaag ataaagaagt tggaacacaa caaggttcaa cagcacttga tgcagtggaa
     2341 aaggataaag attttatgaa tagcttaaaa ggtggagcac cagttcttta tgatacttat
     2401 gataaagcac ttagagattt agagataggt agaactagtg cagttgttgg tgatgaagtt
     2461 ttaattagat actatatggg acaaaagggt gaagacaaat acaaggtatt aaaagacgat
     2521 tttggattag aagattatgt tgtagcaact tctaaagaaa atccagaact ttgtgagaaa
     2581 ataaatgaaa cattaaaaga aatgaaaaaa gatggaactt ttgacaagat ttatgataag
     2641 tggtttaaat agaagataag ttagctgtta agaagggggc actaaaggca tgttacaagg
     2701 tttagagata gttatagcaa tgttttgtat aacattgata gtatcaattc cattggggat
     2761 tggagttgca tttttaagat tatcaaagaa taaattagta agtggtatta cacaatgtta
     2821 tatattgata atgagaggta cacctttact tttgcaaatg atagtcatat tttacggatt
     2881 acctctttta ggaattgtat ttgacagatt tacagctgga gtagtagctt tcttcttaaa
     2941 ttatgcagca tattttgcag aaatatttag aggtggaata cagtcaatcg atagaggaca
     3001 atatgaagct tcaaaagtac taggatttga taagtttact atgtataaga gagtaatctt
     3061 tccacaagtt tttaaaagaa tactagcacc tatttcaaat gaagtaatca cattagtaaa
     3121 agatacatct ttagtatata tattaggatt aaatgatatt ttaagaatat ctcaaatagc
     3181 aatgaacagg gaagcaagtc tgttaccatt atttgaggca ggagcgatat atcttatatt
     3241 tgtagctata cttactaagg gatttgaatt acttgaaaaa aaatattctt attatagata
     3301 aagttacaat attataggag gaggtttttt atatgttgaa aatcaaaaac ttaaataaat
     3361 catttaaaaa aaatagagta cttaaagata tttcttttga gttagaagaa ggtcagattg
     3421 gagttttact tggtaagtct ggtgcaggaa agaccacaat attaaggtgt ataaatggtc
     3481 ttgaagaatt tgatagtgga gagattataa tagataatga ggtaataaaa aataagagag
     3541 atatggcaaa aatacgagga aaaataggta tggtttttca aaatttcaac ttatttcctc
     3601 atatgacagt ccttgaaaat ataattgaat ccccagttaa tgtttttaaa gttcctagaa
     3661 aagaggctga agagagggct agagaacttt taagattagt tgatttagaa gataaattaa
     3721 attcttatcc atttgaattg tcaggaggac agcaacagag agttgctata gctaggtcat
     3781 gtgcattgat gccaaaagtc ctttgttttg atgaacctac ttctgcactt gatattgata
     3841 ctattcaaag agtagtcaat ataatgaaca gacttaaaga caaaggtatg acaatattaa
     3901 taattacaca tgatgttgtc ttctcaaata atgttgcaga taaaattata agtataaaag
     3961 atggtatagt agaaaatgtt caaataaaag aaaaaattgt ttagagtttt ataaatataa
     4021 actagggtag aattttataa tataaataaa gggcaagtaa aatcaaatat actatgccct
     4081 tttgttatct caaaatttaa tcttatattt tatgtttaag ttacattata atttataata
     4141 aaaataaaag gactatttaa atatataatg tgaataatgt ttaataattt gaaatatgat
     4201 aattttttat gttgaaagct tataatgatt atgatataaa ttggttatag tatacaattt
     4261 atgggtataa caataaaaaa ttagaaagga atttttataa aatgattaaa ttatatggat
     4321 atacaaaatg ctctactgtt aaaaaagcta aaaattggct taaggaaaat aatttagaat
     4381 ttgaagatat agatatggtt caaaaccctc ctagtaaaga ggagttaaaa tcaatttata
     4441 agactagtgg atatgatata aagaaatttt ttaatacaag tggtatgaaa tatagagaat
     4501 tgggtcttaa agatattgta aaaactgaat ctgatgataa acttttagaa atattggtaa
     4561 gtgatggtat gcttattaaa agaccattac ttttggatgg taaaaatgta ttattgggtt
     4621 ttaaagaaga tgtatggaaa agtactttgc taaaagaaga ttaggaagag ataggtgtgt
     4681 tgattaaaat tattaattaa tacacctata aatttatgta ttaaatctaa tctttataaa
     4741 tattaattag caaattcaaa tcaaaaaaat tcatatcaac aaacatatta cttcttatta
     4801 caaattatat catatgtttt atattaaaat attataatat tacaacgaat tgttacaaaa
     4861 ttacttatta ttaaccatga acatttgttt tgtgctatca tatttatata agggaattgt
     4921 cataaaaaat atcttgttca tacagtttta tatagaaaaa agaaatgaat cttttcttta
     4981 tataagtata ttttgtaaat tgcctctata tttatagttt aaataatagt ggtattaaaa
     5041 atctgacaac aaaaataaaa ctttcaaaaa attaaatcta aaaagaatag gagataaata
     5101 tgagtattga agatttatat gattttgaat gtgttccttt gaacaatgag attgatattg
     5161 atgttttatt tgaaaagatg atagaagatg gaaaagaaaa agaatataca ccaattatag
     5221 tcattgatga aaaagtaggg ctattaagaa aaaatataga tatgattact aaagagtatg
     5281 gttctcttga aaactataga gagtattgtt taacaaaata taatgaaatt gatgtaaatc
     5341 aattttttga ttttaggaag agtgagattt cagaattatt aaaggagcta attgatttag
     5401 aagatgattt ttatgattat aaacatttta gacccattat gaatatagat atatttcatg
     5461 aatataacaa agtttacata gctaaaattc caacaattaa accatatgaa gtatttgcat
     5521 acatacctat tggcggattt aatgattgtc ctagagatga agaacatata gctattgcaa
     5581 aatattggta tgaaaagcat ggaatctttc caatcgcaat tggatgtgat acagttcaat
     5641 attctgtaaa aaatttaact aaagatggta aaaaatttga tgacttatgt attgaattag
     5701 tattttattg tgaggatatt attatacaag ggtatgaaac cttaaaggct cttaaggatg
     5761 tattaaaacg ctctacaata gtgctttttt ggtgggattg atattctatc atttagatag
     5821 tattaaattg ttagtcacca agaatccact tgctttagtt atagggagtg tgtcaaacta
     5881 ggtttttata cacagtgtag catagtaata tgtttaaatt acaaaggtta aaaaaatact
     5941 ttaatatttt taatattata attaatagat ttaaggtaat tataatttat aaaataaata
     6001 ctttatatgt tataatcatt aagaatgtaa aaaaataata tatagtttta tagttcatat
     6061 ttttccagat atggaggtaa attttgtgaa ggaaaaagaa aaattagata aattaaaaaa
     6121 aatgttactt gaattaggca gtgttgtagt tgcttattct ggtggagtag atagtaattt
     6181 tttgcttaag gtcgcaaaag atacattagg tgaaaatgtt atagctgtga ctattcatgc
     6241 aatgatgcat tcaagtaggg aaattgaaga ggctaaacaa tatactcaaa attttggtgt
     6301 taaacatatc atattaaata tagaaaactt tgatttaaaa gaatttaaag aaaatggtgt
     6361 tgatagatgt tatcattgta aaaaatatat attctctaaa ataaaagagg tagcaaaaga
     6421 acataatata aagtacatag tagatggaac aaatatagat gatttaggag actatagacc
     6481 tgggcttaag gcattgagtg aattaggagt aattagtcca ttaaaagata gtagtttaaa
     6541 aaaagaagaa attaggtcgc tttcaaaaac attaggatta aatactttta ataaaccatc
     6601 atttgcatgt cttgcgagta ggatacctta tggagttgaa ataacagatg aaaatttaag
     6661 aatagtagaa aagagtgaag aatatctatc caatttaggt ttttctcaat ttagagtgag
     6721 aatgcatgga gatatagcta gaatagaagt tggacaggaa gagctaggta aattttttga
     6781 aaataacaat tttaataaag ttgatactaa attaaaaata tttggcttta aatatgttac
     6841 actagatatg tcaggatata aaatgggaag catgaattta aatgtgtaga ttattttaaa
     6901 aataaataag ttttatagtt aatataagga aacaggaggt tttatgaaaa attatacgtt
     6961 aatatcgcca tgtttttttg gaatggaaaa aatgctggct agagagatta ctaatttagg
     7021 atatgaaata ataaaaacag aagatggaag aataacatat aaaactgatg agtttggaat
     7081 agcaaagtca aacatgtggt tgagatgtgc tgaaagagta catcttaaaa ttgctgaatt
     7141 tgaggcaaaa agctttgatg aattatttga aaatacaaaa agaataaact ggtctagata
     7201 tataccttat ggagctcaat ttcctatatc aaaagcttcc tctataaaat caaaattata
     7261 cagtacacca gatgtacaag ccatagtaaa aaaggctata gtagaaagct taaagaaaag
     7321 ttatttggag gatggtttgc ttaaagaaga taaggagaaa taccctattt ttgtatttat
     7381 acacaaagat aaagtaacca tttctataga tacaacagga gatgctttgc ataagagagg
     7441 atatagagaa aaggcaaata aagctccaat aagagagact ttagctgctg ggcttattta
     7501 tttaactccc tggaaagcag gtagagtttt agtagaccct atgtgtggtt ctggtactat
     7561 attgattgaa gctgctatga ttggtataaa tatggcacct ggcttaaata gagagtttat
     7621 atcagaaaag tggagaactc ttgataagaa aatatggtgg gatgtaagaa aagatgcttt
     7681 taataagata gataatgaat ctaaatttaa gatttatgga tatgatatag atgaagaatc
     7741 tatagatata gctagagaaa atgctgaaat agcaggtgta gatgaatata tagagtttaa
     7801 tgtaggagat gcaactcaat ttaaaagtga agatgagttt ggatttataa tcactaatcc
     7861 tccttacgga gaaagattag aagataaaga cagtgttaaa cagttgtata aggagcttgg
     7921 ttatgcattt agaaaattaa aaaattggtc gtattatttg ataacttctt atgaagactt
     7981 tgaatatgag tttgggcaaa aagcagataa aaaaagaaaa ttgtataatg gtatgttaaa
     8041 aactaacttt ttccaatatc cgggtcctaa gcctcctaga aataataaat aagttttaca
     8101 tgatttattt gtaaaatata aaattttatt aaaataagta aaacattatg atgccctgaa
     8161 acgtctaatt attgtgagga gatttttgtg aacaaattta aagatttata ggattaggag
     8221 gagttaaatg aaagtgttaa agcttattac tgtagtagcc ctgatgatgt tatttgttac
     8281 tggatgtaat ataaaaactg aatctccaga acaattagcg aagatacctg actatgatga
     8341 tacaaaaaaa gtattgtatg atggtattga ccagttacta aaaccagatt catctatgat
     8401 attgccttct aatacaaaag aagtaggaaa aataaataag gtagatttaa acagcgatgg
     8461 aattgatgaa ttagtagtat ttgaacaaaa agaagattta agtaataatg tgagtcaggt
     8521 agggtttgta accttgagtt acaatggaga aaaatacgta cttggagacc attttttaga
     8581 aaatggcgaa tcaatagaat atgctaattt ttatgatttg gactcagatg gatataagga
     8641 agttatctta ttggttaaat ccaaagacaa aacgaatatg catatatata aagtagtaga
     8701 taatgaaata acaaaaatat atgacttgga tgcatcatgg cttcaaaata aagaagattt
     8761 taatgacatg aaagtaaaaa ttggatatat agatggagat gacaagttag acatattgat
     8821 gcttcatttg aataataaga ctaatgaaat gtttgcaagt gttgcaaatt ttgatgggaa
     8881 aatgaaaatc aaagattctg ttaagtttga aaatgtaaaa aacttaagtg aattatatat
     8941 aacattaggt aatgttgctt catctgttgg aaattcttct gcagctataa aaggtattgt
     9001 acttgatatt cctatattga aagataataa ctatattacg cagatacttt atatgaaaga
     9061 tgggaaaatt aacaaagctt ttagtgatta tgataaaact attactaaat cttattatat
     9121 acctgtagat gatattgaca aagataagat tatagaaata cctatagttg caggcagtac
     9181 aggtaataat aaaaatactt atagttctaa atcatctgca actataagtt ggtatagatg
     9241 gaatggaaaa gaaggtgctg actcaagttt aatatttaca agtcagatat attataatta
     9301 taaatataat tttaaattat ttattccaaa taatttattt gataaaatac ttgttgaaca
     9361 ggaatttgtt ggagaaaaag cagtatttaa attttactat tttgactatt cagaccgtaa
     9421 gaatttattt aatatagtag tagagagtaa aaataaactt gaagatagaa aaaatacagg
     9481 tactcaaaat tctattgtac ttcaagagag cgatgaatat actttcttac tagttgtaaa
     9541 caatgcaaat gaaatggata agctagatat gactatagac gcattaaaag aatatttctc
     9601 attaatatat ggttaatatt atactcaatt ggaggtttta ttttatgaag gaaaagatac
     9661 ttatactaga agatgaaatt ggtattagaa gttttgttag tataaactta aaaagggaag
     9721 gctatgaaat agttgaggca ggtactggaa gagaagctat agaaaaaatg acaacagaaa
     9781 aggatattac aatagctctt ttagatgtaa tgcttccaga tataagtggt atagaagtat
     9841 gtaaatttat aagggagaat tttgaccaag taggtataat aatgcttact gctaaagctc
     9901 aagaagatga taaaatagaa ggatttatct caggagcaga tgattacatc ataaaaccat
     9961 ttagtataaa agagctttta gtcagagttt ctgctcttct tagaagagta gcaaaggatg
    10021 attcaagtgt taagtcgagt gagatagttt ctccaccatt tatacttgat atagacaaaa
    10081 gaaaattatt taaaaatgga aaggaaattg agcttacacc aactgaattt tcaatagtga
    10141 aatatctaat atcaaatgct aagcagtcgt taagtagaga ccagatatta gacgaagtat
    10201 ggggaactaa ctatttatat gattttaaaa tagtagatgt aaatataaga aggataagaa
    10261 ataaaataga agatgaccca tcaaaaccaa aatatataca aactatttgg ggttatggat
    10321 actgttttag aaaggaagaa taatagtgtt acattttgaa ggtctgagaa aaaaagtaat
    10381 aaaaaactat tttataataa ttattataat ggttactctg tttgaaggat tgttcatgtt
    10441 ttacatacaa aactactatt atgattctgt caaacagcta cttgaatctg aaataaaata
    10501 tgctgatgaa tataatgcta ttacaatgga aactacaagt tttgagaaaa aagtaaaaaa
    10561 tatatttgat aaacaaccct taactaaaaa ttcagaattt ggaatttcaa taatagataa
    10621 agataaaaat attatattag accaatatgg ttttaaaagt aaagaaaaag caaactatga
    10681 agatgttaac aatgcattaa aagatataaa aactaaaaat ttaacacctt atacttatag
    10741 aataccagat acaggggagc atgttatgag tatctcctta ccacttaagg taaataatat
    10801 aatagaaggt gttgttagat atacagtatc attagatgct attgataatg caatattaaa
    10861 gcaagctaca tggcttatat tagcaggaat atttatactt attatagcta tactaataag
    10921 tcttaaattt gctgagactc ttataaaacc attacgagag ctaaagaaat ttgcaaatga
    10981 attggctgta ggaaattata atataaaatt agaaaagatg aagattgtag atgatgaaat
    11041 tggtgattta gcacagacat ttgaacacat ggcacatgag attgacaaaa gtgaaaaatt
    11101 aaaagaggaa tttatatcat ctgtatctca tgaactaagg actcctctta catctataaa
    11161 ggggtggagt gaaaccttag gttatgaaag tataacaaga gaagaactag acttaggttt
    11221 aggcattata caagatgaaa cagaaagact tataaaacta gttgaagaat tattagactt
    11281 ttcaaggctt tcttcagaca ggataaaact tcatgttgat atagttgatg ttgaaggttt
    11341 aattgtaggt gttgtaaatc aacttaaagt taaagcagct gaaaaagata tatcactttt
    11401 atttgaattt gaaaatgaat ttatagagaa cattcaagga gataaaaata gattaagaca
    11461 ggttctcata aatttaatac aaaattcatt taaatttacg agtcaaggtg gttacataaa
    11521 agttgtagct tctcaagatg aagagataac aaccatatca gtagaggata atggttcagg
    11581 tatagaaaag caaaatttaa ataaagtgtt agataaattt ttccaagaag attataataa
    11641 ggctggtagt ggattaggac tagcaattag taatgaaatt gtaaaacttc atggtggaag
    11701 aatgaaaata gaaagtgaaa agaatgttgg aacaaaaata acttttaata taaaaaataa
    11761 atttgctaaa caagcataaa ttcttagaaa gaggattaag atgagaaaca taaaaatgat
    11821 agtagcatac gatggttcaa gatataaagg atatcaaaaa ttaggtgaca ataatatgac
    11881 tattcaagaa aaacttgaaa atgttttaag taaaatgact aatgaaacag tggagataat
    11941 aggttctgga agaactgata tgggagctca tgcaagagga caagtggtaa attttagaac
    12001 taattgtatg gattctttgg ataaaattca aaaatattta tatgaatatt taccagaaga
    12061 tatagttgta aaaactgttg aagaagttga tgaaagattt cattcaagat acaatgtaaa
    12121 atcaaagact tatatgtata aaattgacaa taataagtat cataatcctt ttataagaaa
    12181 atatgctact catgtaagta aaaaattaga tttagataga atgagaaaag caagtgagta
    12241 tttagtagga gaacatgatt ttactagttt tgcttcttct aaatctaaga aaaaatcaaa
    12301 tgtaagagaa atttattcta taaatataaa agaagatgat aatgttatag aaatatatgt
    12361 agaaggaaat ggatttttgt ataacatggt aaggataata gtaggtgctt tgatagatgt
    12421 tggtctaaaa agaagagctc cacaagatat taagtatatg cttgaatcaa aagatagatg
    12481 tcaatcatca gatactgcac cagctaaagg actatgtctt tggaaagtaa catattaatc
    12541 aattatataa aactctcttt aaaataaaaa taaaataaat tatatagttg acataaatgg
    12601 aaaaataaac tattatatat tttataagag agatataaaa ctttatattt aaatcctgtg
    12661 agaaagagag taacttctat gtgttttata gagagctgag gatggtggaa gcttggcaaa
    12721 taagtattag tgaaaagaac tttggaggat actaattgaa tttagtatgt tagtaggtaa
    12781 tctcgcctta agagaaagag tggataagtt tatcttatca attagagtgg taacgcggat
    12841 atatttcgtc tcttggtttt tccaagaggc gttttttaat atatttaatt attagtgttt
    12901 atctggtatg ttgaacattt actaattgat tagctaagtt tatcaataag agtggtaccg
    12961 cggatatttc gcctcttagt attttaaaat actaaggggt ttttttagta ttaaaatgat
    13021 tttatgtgag tctaaattct cagagtcatt caatattaag aatttctata aaataaaaat
    13081 tataatttaa gattgggagg aattaaaaat gaaggaaaaa gtagtattag catattcagg
    13141 aggacttgac acatcaatca taataccttg gttaaaggaa aattatgaag atatagatgt
    13201 tatagctgtt tgtggaaatg taggtcagga agataaaatg gaagatgtat atgaaaaagc
    13261 tttacaaagt ggagcatcaa aggcatatgt ggatgatata agtgaagaat ttgtaactga
    13321 aactatattt aaagccgtaa aagcagaggc taaatatgaa ggaaaatact tattaggaac
    13381 ttctttagca agacctataa tagctaaaaa attagttgaa gttgctcata aagaaggtgc
    13441 aaaatatata tgccatggat gtacaggaaa aggtaatgac caagttagat ttgaagctac
    13501 aattgcagct cttgacccaa ctataaaagt tattgcacct tggagaattt gggatataaa
    13561 atcaagagaa gatgctatag actatgctga aaaacataat ataaaggtaa cagcaactaa
    13621 agctaaaata tattcagtag atgccaacct ttggcatgtt tcaacagaag gtggagatat
    13681 agagcaccta gaaaatgaac ataaaaaaga tgtttataaa caatgtgtag acccagaaga
    13741 tgcatgtgat gtagctgaat atgtagaagt ttactttgaa aaaggtgtac ctaaaaaggt
    13801 aaatggcgaa gaattatctc cagttgcact gattcataag ttaaatgagt tgggttgtaa
    13861 acatggaatt ggtgttatag atatagttga gaatagactt gttggtatga aatcaagagg
    13921 tatatatgag actccaggag gaacaatcct ttatgaagca cataatattt tagaaagtgc
    13981 tactttagac aaagatacat tacatttcaa acaaatggta tcttataaat acggagaact
    14041 tatttacaat ggactatggt attgtaaatt aagagaatct atagatgcat ttatggaaca
    14101 aactcaagat aatgttacag gaacagtaaa agttaaactt tacaaaggaa atataaaacc
    14161 tgctggaata tttactgaaa atgctcttta tgatgaagga atatcttctt ttggaaatag
    14221 tgaactttat gaccacaaag atgcagaagg atttattaat ttattcactt taccattaaa
    14281 aatcagagct atgaaagctg gaaaataata aaataaatta tttaagagtg tataaaaacg
    14341 atttttaggt ttttatatgc tcttttttta tttgaattta ttaaattata cagtaaatag
    14401 tataaaaaaa tatattatag ttccaaatgg cttaataatg tgaaaatata agacctaaaa
    14461 tataaatttt ataaatacaa tagttattga ctctctcatt gtaagagggt ttatactgaa
    14521 tctaatgaaa atttatagtg aggagataga ttatatgaga aaaataattg aaattaaaca
    14581 tcattcacat gattatgagt gtatgtggaa tggtatagaa gatttatata taaataaaac
    14641 cggtgaatac cttccaaacg attttttctt tttactgtca ggttttggtt cattttgtta
    14701 tatgaaaaca aataaagctg atttgaaaag aatggtagct ttgggagatg gaaggacaaa
    14761 acagatgtat aaatttttag caccaattgt tggatttgaa tacaaacatc atgagtttaa
    14821 aaagtatgag caagcattaa agaaagcaaa atctgaaatt gatgatggat atccagttat
    14881 tttaggagct ttagatatgt attatctacc atattataag aagctatatc ataaagaaca
    14941 tattcctttt cattatatat taatggtagg atatgatgat gaaggaatat atctgtatga
    15001 ttgtggtaga acagaattat tacatctttc ttatgataaa ttacgtgaaa gcatgaattg
    15061 caattcccct ggattaagca aagaaaatac tatttgcaca ataagaatga atacttcaaa
    15121 gaataaatat aacattgcta gagaagctat tgctataaag cgtgatatgt ttttaaatcc
    15181 acctaaagga tttttgggat ataaaggttt tgaaaagttt attaaagagt tgccacagtg
    15241 gaacactgaa ttggataagg atgattatga taagattttg accaatatgg ttatgttttt
    15301 tggaacagta ccaacaattc caaatgcaat caaaggaatt aaagaaccag atactgttca
    15361 atttaaaggt ggatttgata aaatgagtag aatgctcaac agtattgggg aggaatacaa
    15421 aaacaactct tttatacaag tagctgatat ttttgataaa actgctatta taattgagaa
    15481 aatatccaat attataatag attacttaac tcaaacatgt gatgatacag aacaacttcc
    15541 gttattgttc tctgaggtct tagagcatat gaaaacagga tatttaatct tggatgtata
    15601 aaaaatatat tgttgaccct aacattacgt aatagtgtaa tatgaaaata tagcttaaat
    15661 atattagtag gtattgatgg ctgtaaaatt aaaatttgag gtgtggatat gagaacagtg
    15721 aaacaagttt ctgatttaac tggaataagt gtgagggcat tacattatta tgatgaaata
    15781 ggtcttttaa aaccaaataa aattacagat gcaggatata gactttatga tgatgaatct
    15841 attaaaactc ttcaacaaat tttatttttt aaggagattg atattccttt aagagaggtt
    15901 aaggaaataa tgtcaagcca atattttgat aaggttgaag ctctaaaaaa tcaaaaaaaa
    15961 ttacttattt taaaacgaaa gagactggat gaattgatag agcttataaa tcaaactcta
    16021 agaggagaag gaaatattga ttttaaagag tttgatatga gcgagtattt taatgtttta
    16081 gaagaattta aaagagagca taggaataag gtaattaaaa tttatggtag tgtagaaaaa
    16141 tacaatgaat atatagaaag agttaagtct aatgaagaga aaattgctaa aatggctata
    16201 aaacaatatg gaactattga gaagtttgct aaagctataa aaacaaattt tagcagtgat
    16261 atattgaatt taggagaaaa atttgataga tataaaaatg attgtttaaa agaaaaacat
    16321 ccaaaattaa aagaattata tagaaagctt gtagaagatt taagtaggaa tccttcttca
    16381 acagaccttc aagaaatagc aaaagcgata acagatatat ctaaaaaaga ttatgaaatt
    16441 ttctctatgg atactggtga tgacaactgg tattatatgg ttcaaaatta tctagtaaat
    16501 cctatgtgga tagaagaagt agataaaaag tatggaagtg gagcaggaaa gtttattgga
    16561 caagtactaa agacttatct aagagataga aagccaaaga taaatacatt gtatgaaaaa
    16621 cttgtagaag atttgagtag agattgttct tcaagggaag ttcaaagcat tgttgaagaa
    16681 atagacaatg aaatgaaaag aagtaatgaa ttttataaaa tagacaatgg tgaaagatac
    16741 tttgattata tgtcagagct ttatttacaa gattctaact atataaaagt aactgataag
    16801 aattatggtg atggtgcatc taagtttatt ggagaagctt ttaagattta ttttgataat
    16861 aataattgtt gaaaatttgg aagtaaaaaa tatgtaagtt ttataaaagc acaaaaataa
    16921 ggatgtagat tagctccatc tatatcctta tttaaagtta ttaaaatata tagtttacat
    16981 caaacttaac actttcaata atatttccca aatatgtttt tatactttca acttcttcta
    17041 aagattttaa tttattttca gtataaattg ctttgtccag aatattaaac cttaatccta
    17101 tttcatcaaa gtactcatga tttaaaactt tgtaccaatg gtttttttct ttattccaac
    17161 tcgtagatat tgaatcagct tctttttgag ctttttccca atcttcattt tctatagatt
    17221 tttctaaaac agatatattg tctttatatc cttctgtaaa atcatatagt ttattgttaa
    17281 cgtaaaatcc aaataataca aataagatag tccatagtat aacaaatgtt gtagatttca
    17341 atattaatca ccctttttat tttgaataaa tattttgtca ttttcatcta aaacacaaat
    17401 aagaacatct ttaaaagttt ctatgtgatt agattttaaa atacccatta accagttagt
    17461 atctttttga gctatgtcta gatttttatt tattattcta ccatccagta taagtgggat
    17521 aggtaaatga ttaaaagctc ttggaggagt actattgtag cttgatgctg gtacaacact
    17581 tagattacca tcagtctcca aaatagcata ttgtacatct tttaggttaa agtatccttg
    17641 aatcctaagt tgttctaata attcatctat actaattctt tcttttttaa gctctttata
    17701 tacaattttt cctttatcta ttaatacaga aggtttacct gataaaaatg aacttaattt
    17761 tctgcttttt aatgataaga atgaaattag agtctgcatg attacaagtc cagatattgc
    17821 tgcaacacca tttatgattg gtatattatt attttccatt gggacagatg caacttctgc
    17881 aattaatagt gttataacta aatcaaaaca gttcatttca gctatttcac cttttcccat
    17941 gactctaagt gcaattagca ctgttatgta taatataata cttcttatta atactactgt
    18001 catatctatc aattactcct ttaaaaaata tttacactta gttagtatat cctatataaa
    18061 aaatttaatt caaagtataa aaaaccttaa ataattggat tcaactattt aaggtttttt
    18121 tgataatttt aatattaaat tttttatgga ttttctgtta cttttattta ttttaataac
    18181 agattcaaca aaactctttt tatctcctaa ttttaagata aaatcaggat attcttcaaa
    18241 ttcattgagt tttattaatt tgaaagaaga agatagattt ttaaagttaa taattttaga
    18301 gttattcact aatacacttc tttttttaaa ataaatttct tttttactta tatttagtat
    18361 agttaatatt tgtttaagat atattattat atcttctgga gttctatcaa atttgagttc
    18421 aaaattttca tcttcaaagt agggaatata atataaaggt gttttgagag caggtaattt
    18481 attatataat tcttcaagaa tatcgatatt tttaggggag ttaaagaaaa agcatttaca
    18541 tacattcatt aaatccacag catctgaaag tgagttatgt ttaatatctc cttctacaga
    18601 aaaaattttt ttcatattca gtaaagatat ttgcttagat aagattctat tattgtatgt
    18661 aatatgttga gatataaaag gttgaatgtc aatcatcata ttaaataact ctaagcattt
    18721 acctgtatat ttatacactc taaatgaagt tagaaggcca gttatatcaa aatcacccca
    18781 attatatatt gtaacatcat caaatttaca aaaccattta taaaaatcat ccataacata
    18841 taaaagatta ggagcattat tgatatctag ttggttcaat ttggttaaat ttttacattt
    18901 atttgaaagt attttattgt attttggctt aactaaagag taataattat ctattgtatt
    18961 aaattcgtta tcaactaaaa ctccaccaat agaaattaat tccgcaccat tatattcttt
    19021 tggtttattt ttattatcat ctagtatatt aaattcaaag tctataaata acttgtattt
    19081 cataaatcta aagcacatcc tcaggtaaat tatttattga gcctaagcat cataagaatc
    19141 aatagatata atgactctaa acatcaaagg ttcattacaa cttttattta tttcataatt
    19201 taattcaaat aaatctttta agatataatt tataagtatt ctttcccaac ccatttttaa
    19261 attaacttta gagtctatta atatattttc tatcttttta aatatttcta tatttgctgg
    19321 tattatactg agctcaatat tacttttaaa cgggttagac tgtaaatctg ttataagtat
    19381 attttttaat tcctctgtaa gttcagaaat taaactatca cctatgtatt tttttatgat
    19441 ttcctctcta atttctttta aatttagcaa tattagtacc tgctacttac atagtagctt
    19501 ttcctttcct tttaatacta ttattcattt ttgaatctta tttagatata ttttaagatt
    19561 aaaagtcttt agctatataa ttttttaccc atttttaact tatattaaca tattacaggc
    19621 ttatatctcc accctgttta cattgaggat ggagtatatt gcctattttg ataaaaatga
    19681 taggttgcta tttgcctatt cctttttctg ataatttttc taacatatct ttggtcattt
    19741 tatctaaatc ataactaaac ttaaagttcc attcttttac tgcactacta ctgtctagag
    19801 agttaggcca agaatcagct atactttgtc ttacagggtc tacatcatat tctatcacaa
    19861 aatcaggaat atattttttt atagaatcag ctatttcttc aggagaaaag ctcatagcag
    19921 taatattaaa agcatttcta tggatgagtt tatcagctgg agcttcgatt aaatccacta
    19981 ttgattgaag tgcatcaggc atatacatca tatccatttt tgtaccttct gctatgtaag
    20041 atttatatct cttatttttt aatgcctcat aatatatatc aactgcataa tctgtagttc
    20101 ctccaccagg aggcgtaaca taagaaataa gacctggaaa tctaacacct ctagtgtcta
    20161 ctccaaattt tgagtgataa taatcacata gtaattctcc agaaacttta gtcacaccat
    20221 acatagtatt aggtctttgt aatgtatctt gaggagtcat attttttgga gaattttcac
    20281 caaaagcagc aattgaacta ggtgtaaaaa atttacaatc caattctttg gctatttcaa
    20341 gaccatttat taatccattc atatttaagt tccaagcttc tagaggttta ctttcagcaa
    20401 ctgcagaaag taaagatgct agatgaatta tagtatctac atcatatttt tttgcaattt
    20461 caaaaaaacg attcttatct gtaacatcta atatctcaaa tataccagat tcacatactg
    20521 gattaccttc ttttactctc cttgaactag cgattacatt ttgttctcca tactcatttc
    20581 taagctttat tgttaattct gaacctattt gtcctaatgc acctgttata agtatttttt
    20641 tcaattttac aacctcctaa gggtttaatt tatgtagtac tacttatttt tattttagca
    20701 aatcttttgt ttaaatacaa agaattaaag ataataatat acgacttaat tgaatgaagt
    20761 gcagtaagtg cgtaaaaatt taaagctaat atataatggt ctattgtata acaataaaag
    20821 agtagattaa attattatat atagattgtg tgactaagtc acagaaaata gagctaattt
    20881 aatatataat aaaagcatgt caagtaaagc tttaaattaa agtaacttta tataaaaagt
    20941 aatataaatt gataaaatta taaatttatt tatagtgaat ataggttgga ttttatagat
    21001 acaaaaatag tatatatgat atgtagacca ttagcatgtt taaagtagca aaacatataa
    21061 aataaaattt gaaaggaagt ataaaaatga caagaccatc aatatatcat agccaaggat
    21121 acacttgtgc agaggcatta ataaagtctt ataatgagga acacaacaca gatataccaa
    21181 tctcaatagg aagtggtatg ggggttggaa tgaatgttgg aagtgtttgt ggagctgtaa
    21241 atgctgctgt tgttataata gggtatttaa atgggcgaaa tagtaattta gatgaaaata
    21301 tagcaaggaa gtattcaaga gagctattga atagagtaag aaataaatac agctcagaaa
    21361 tatgtgtatc tcttaaaaaa aataaagtaa cttgtgaaga aataataaat ttcacatatg
    21421 atgctctaaa tgatatgcta aaaaatcaaa aataattcta agaaacaagt attttacatt
    21481 cgatagaata cttgtttttt tatgatattt ttaataagta ttagtttatt ataattttta
    21541 aatcaatttt attatatttt aattgaaata atctactttg aaaattacta actgacaaaa
    21601 gaatatgatt atagtataga aaaaatgtaa attatttaat attaagtgag agtatatgct
    21661 tacctatata aaatcgtata aattaatggc taaattt
//
LOCUS       DAMKNB010000062        21599 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.064, whole genome shotgun sequence.
ACCESSION   DAMKNB010000062 DAMKNB010000000
VERSION     DAMKNB010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 21599)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21599)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21599
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.064"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            272..973
                     /locus_tag="PC494_002578"
     CDS             272..973
                     /locus_tag="PC494_002578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5058 family protein"
                     /protein_id="HDF3913069.1"
                     /translation="MKFQEMINSPGLWIVSSFLVIISVVQAIVFMKEALKEASNLGIE
                     RKGIKAAIRSASVTAIGPSLSPVITLLSLVAVIGAPTTWMRLCDVGAARTELGVISLT
                     SNLSGVEVGSAAFGAEAFSYALWGMALNNLGWLFVVFILGHRMRGIVEKMNMKYNPTW
                     VKKLLAGATVGLFAYLLSNQIKTFEIPKLTPAIISAIVMLVLTTLFKKNQRLQELSLG
                     IAMLIGMFGTQIILL"
     gene            999..1655
                     /locus_tag="PC494_002579"
     CDS             999..1655
                     /locus_tag="PC494_002579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3913070.1"
                     /translation="MYDKKMIKIGRISIGLAIIANFIPAIYVGIRFGQMPMLSVIFQI
                     WGLVAATYGVSWIVQPIAYYPTLGAPGSYIGWLAGSVGDIRMPAASMAQKIAGVEAGT
                     HEGEVVGTIGTCCSIFVSASMITIFTIVGYKVIPLLPEFVTNSFNYILPALFGAIYVD
                     IARKDIRAGGCTIAVALAIMYFGEKIGIPGGLLTLFIVLGGILITRVFFVIDNNKTKE
                     "
     gene            1760..3400
                     /locus_tag="PC494_002580"
     CDS             1760..3400
                     /locus_tag="PC494_002580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-aminoacylase"
                     /protein_id="HDF3913071.1"
                     /translation="MFDVKIVNGIIVDGTGNSRYKSDVGIVGDKIMAIGDLSQKEAKE
                     TIDATGKFVSPGFIDFHTHSDLSLVYDKYTRSRIHTGVTTDVIANCGIGVAPIREEKK
                     QELIDYLGTRIIGTIPTKLELHWNTMQEYFDYLTENSPAVNVVAYVAQGPVRINEMGF
                     SKEPATLEQLKNMKLEVRKAMEAGCVALSSGLVYLPGAYTKKEEMAELCKELIPYNGY
                     YISHIRDEGDEEMEALDEAIYIAKTAGVPLHVSHLKVMGHKNFGTIDEVFKKLDEAEA
                     DGLEVTFDCYPYTAGMTSLGALLPPWAFEGGVENMVKRLEVQENRDRIIKELEEGIPG
                     WQCFYQLAGGWNGVVLASVMTEANKYVEGKTLMEVAKINGENPFDTFFRLLIEEKSKI
                     QVVVHTQGQEDTDKVVCHPKSCIGSDSMDLSTEGLLSLGKPHPRAFGTFGRIFSYYVR
                     EKGMLTFEEAVKKITYLSAKRLGIYKERGLLKENYFADIVVFDPDTIEDKATYSNPKQ
                     YTVGVEYVLVNGKIALAGGKQTDVCAGRVIKNPLSIAK"
     gene            3758..5080
                     /locus_tag="PC494_002581"
     CDS             3758..5080
                     /locus_tag="PC494_002581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3913072.1"
                     /translation="MKILYVGPGMVIDKILAVSKKNFPNIEADFLRYDRYIEVPDLLE
                     KYRGRVDAVLFTGKSPFKFFEKRQKDFVLSDYIPRHETTLYRVLLEITYLLKLDISRL
                     SIDTYDKAMMKRLYKEIGVEFKDEHMFFAEQKYLEEDYIKFVLEFHKYNYQNNDVCCC
                     ITGLEEAYHIMKKDNIPVVLALPSEDVMVQSIKNIQMRYIAKKNNENQIVVLAIKLNM
                     PSEYSLMKEDEYAYLSQRIKILDKLYHFNSRIDGVLVEQSRSEFMIFTTKKILELETK
                     KYRDIYLLDMIREVSVINTYIGIGYGKTANEAKFNAYESIKMAQSQKNDAAYVVFENG
                     EIMGPLKPNPTVKEKNSFDERFYQIATETGLSANTVYKVFNKIINSGKTEFTSKELAT
                     ICGVSIRTMDRIILRLCDSGYCEVVSEQLMSKYGRPSRILRFKPFLLF"
     gene            5277..6284
                     /locus_tag="PC494_002582"
     CDS             5277..6284
                     /locus_tag="PC494_002582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="HDF3913073.1"
                     /translation="MGKYQYSKKVVRNYFEALENATGDEVENVLKQHMKSDYNWKGVY
                     PFREQEGTENVADVFWKPLKKSLSNMQRRQDIFIAGTNEIDNSEWVMSMGHFMGLFDN
                     DWLGIKHTRKMISLRYAEFNCVQDGKIAKTGLFVDIIGFMIQAGVNPLPPQTGSYFVY
                     PGPIDHNGLLFEDADEVEGVKTLALVNKMVDDLSELNESGAMGCPPEILEKSWAKDMI
                     WYGPGGIGASYTIPRYQEQHQLPFRNNLKGKTFNGHVCRFAEGNFACFFGWPNLTNVP
                     CGGFLGLPGGEVKADMQVVDVYYRKGDKLQENWVLIDIPYWLKQQGLDILERTKSIFN
                     A"
     gene            6322..7734
                     /locus_tag="PC494_002583"
     CDS             6322..7734
                     /locus_tag="PC494_002583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ester cyclase"
                     /protein_id="HDF3913074.1"
                     /translation="MASTNKNNATSKEEEKEVSTSVLESCTVKEKKAKMNQTNFSNIN
                     ENQTNENKTNTYKGNIDKGNIDKTNTNKSDINKVNIDTVDTDKLNTNTLTEKNKKVIF
                     KGEDNMSSTKIYYGDSLEVTPVGVMDYNDFSKQTKREQEIPGFDSKYRDFVDYIMKIT
                     HNIWEEKGIGVIYDTYHNNVTMHCGSSNLVGIKDVISNTLQTLHAFPDRRLIGQNVIW
                     SNFGADGFLSSHRVLSTATNLGDSNFGPATGRKINFRTVIDCATTNNRIHEEWLVRDN
                     LWIVTQLGLNPQEVAKSMAKASESKVLSLQSTYGICESMDGQFMPTKYQAKDDSVGEM
                     MLEMTSRIYNYKYINEVKKYYHDNAVVHFICDKDLNGYDEIQGMIVSLLASIPNGSYE
                     VERVTCNQREKNEGYDVSVRWRLRGINEGIGFFGQPSGKHIEVMGINHYHILQGKVKE
                     EWITFDGMDVLKQMYMGVEE"
     gene            7878..9143
                     /locus_tag="PC494_002584"
     CDS             7878..9143
                     /locus_tag="PC494_002584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDF3913075.1"
                     /translation="MKTTVEIENDIILGKDYSNLKRGIAFFSIALIYFFYCYNFMVGT
                     FIKPTMIYALADGGFGFSLKQTEEIFAVMSFGTIPGTFIFGVISTKIGKKRTLISVAL
                     LIGLTTFIPMLSPTNIMLWKIARLCTGVVLGGVFGTAMPLVADMFPSKYRGKLAAILT
                     ALFSLAMIFGGKVYGVLGDANWQILMYTAIIPPIVGAILAIFFVPDDLEYTKELVKKG
                     KETGEKISYISMYKGKYLWIGLGTILLSGANFTAYSAFSNNATTYLVTGIGMSAAVAG
                     SIYSLQGIGQLVGYLFWGSIADKFGRKIPFIGMALAAVFVFIYTKLGGDNTTTFYMIS
                     VLLGVAVGYSGAWGAYYTELFPSKYRSLSSGMSFNGGRIISTFAIPAIAGTASGTLGM
                     MTIFYISIAVFVAGAIVWLFLPETLNNKK"
     gene            9185..10783
                     /locus_tag="PC494_002585"
     CDS             9185..10783
                     /locus_tag="PC494_002585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:solute symporter"
                     /protein_id="HDF3913076.1"
                     /translation="MISSIDVCIIIGYLLLMLVIGYYSGKDNKNQEDYFLAGRSMPWI
                     PIALSVAATMISANGFIGGPGWAYVDGMYPVMVNITVPLAIFFALSITTPVIYKLKIT
                     SIYEYMGLRLGNYSRGLTIIQFFINSLIQASSMVYIPVLIIQMITGWSLYALVPIVVL
                     VSIIYTLLGGIKAVIWTDSIQMIVVISAVFIVIIVALKGMNLSFFDTLQIAQQSGKLN
                     TFDFSRDISVTNTFWATLIGGTVMWIRYFCFDQSQVQRVLTSKSLKCAKNSFVVSAFV
                     MNLVYYFMLLVGVILFVFYGGRTFETSNEIMITFILNELPVGAIGIIIAGVFAAAMSS
                     IDSILNSMTTVFTKDIYEFYFKKDNKESSLKVTMIITVVIGVVMTGFIIMGFGGSIKS
                     ILDLVGNYISYFAGPATGAFVLAMFTYKANDKGVSIGFIVGLVLGFFISNKYNVSWLW
                     NPAIGATITLIFGYIFSVILKKNHNADDIKKYTAFGMRNHLISQGMDKVDGVSIVPFS
                     LGKQELIVLAFFIIQYIILFLIQF"
     gene            10818..11840
                     /locus_tag="PC494_002586"
     CDS             10818..11840
                     /locus_tag="PC494_002586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HDF3913077.1"
                     /translation="MNQKKVHYNKSATSKDVARLAGVSQSSVSRAFGSANGKGVKPEV
                     RERIFRVANEIGYVPNLVARGMISGKTNVIGLIVGDSLGPFYNRIINLFVEKIQEIGK
                     QCLVFKVPRQQSIDSIISKVIQFQVEAVIITASAMNKVMAETCEENNIPVILFNRFIP
                     GIKISTVYVDPIEGGGMAAEYLLKKGHKNIGYIQFTRETSEEMEKKIGFYSKLRQSGI
                     HNLKEESANYDYDSGYEAGKRMLALSNPPTAIFCTSDLIAIGVMDAARFEYKLRVPED
                     LSVIGYDDIQMASWKSYNLTTIRQPLDLLIEKTINILKSLLNEENPESVVEMLKPELI
                     ERGSTL"
     gene            complement(12317..13720)
                     /locus_tag="PC494_002587"
     CDS             complement(12317..13720)
                     /locus_tag="PC494_002587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HDF3913078.1"
                     /translation="MKMLNNFFKKINNPAPVFAQTKMERDNQTDDSLSTKPKTTFRDV
                     AGLDEVKEELFEIVDFMKSPQKYQKMGAKIPKGVLFYGPPGTGKTLLASAVAGETNSS
                     FFNVTGSEFVEKYVGVGAKRVRTLFEKARKEAPSIIFIDEIDAVGAKRHLESNNEKDQ
                     TLNQLLVEMDGFNKDSNVLIIGATNRLDLLDEALLRPGRFDRHIHIGAPNYHTRFEIL
                     KVHTDDKPIDKSVNLELLAKKTHGFNGAHLSNIANEAAIFAVRDDSECITSEHFDKAL
                     ERVIAGLESKNSALVEKEKKIVAYHEAGHALVSDIVGICPIQKISIVPRGQALGYVLQ
                     LPDEDRYIYTKDELIGKIKILLAGKASEELIFNHKSTGAKDDLKKVTEIANQMVCEYG
                     MSNLGFMTIDGNDKTFLCDKVQKEANRIVEICYKETLEMLKDNLEDLHSVSKFLFEKE
                     TMTHEELKDLIGKEAVN"
     gene            14893..15402
                     /locus_tag="PC494_002588"
     CDS             14893..15402
                     /locus_tag="PC494_002588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009528606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HDF3913079.1"
                     /translation="MSKELAINEQIKDKEIRVLSPTGEQLGVMPTKEAQAMANSKNLD
                     LVQISPNANPPVCKIMDYGKFRYEQARKEKEAKKKQKTIVVKEVRLRPGIEQNDLNTK
                     ANNAIKFLKKGDKVKVELRFRGRELGHKDIGKEVMLKFLDIIKEFGEPTKAPAFEGNN
                     MVVIIDPKK"
     gene            15430..15624
                     /gene="rpmI"
                     /locus_tag="PC494_002589"
     CDS             15430..15624
                     /gene="rpmI"
                     /locus_tag="PC494_002589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011721840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HDF3913080.1"
                     /translation="MPKMKTHRGAAKRLKKTGTGKLKRAKAFKKHILTKKSAKTKMNL
                     RKSTLVSDGDAKRIAQLLPY"
     gene            15680..16036
                     /gene="rplT"
                     /locus_tag="PC494_002590"
     CDS             15680..16036
                     /gene="rplT"
                     /locus_tag="PC494_002590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HDF3913081.1"
                     /translation="MARVKKAMNARKKHKKILKLAKGFRGSRSKLYRPANTFVMKALK
                     NAYIGRKLKKRDFRKLWIQRINAAARMNGISYSRLMNGLKLSGVEVNRKMLSEMAIQD
                     PEGFAKLAEVAKAKLA"
     gene            16346..16891
                     /locus_tag="PC494_002591"
     CDS             16346..16891
                     /locus_tag="PC494_002591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3913082.1"
                     /translation="MNEKLMDCFVNPIKCKLLIEIFSNNRTTAKQLGEKFQDISKATL
                     YRYLNKMLKDDIIKVVEENKIRGTVEKVYAMKLDIADDVNKIIDENSGEEYAQLFTQY
                     MMGFLREFYEYAERKEKDILKDGSGFSVCPVYASIDEIVEVSKKIASILEPLRNNSHE
                     EGRRMHSIGVIITPPKKDEGK"
     gene            17326..19251
                     /locus_tag="PC494_002592"
     CDS             17326..19251
                     /locus_tag="PC494_002592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HDF3913083.1"
                     /translation="MKIKFVIMPLVIFLMVLFVGCQSTKDTEVKAKDTEIKILGTGDL
                     HSILTDSMVSYVNEEREKNKNLLMVDAGDFYGTQSREMWEWSSGKKLINIKRNGRAEY
                     DDIIKSSKDEVPIVKDMAKLKYDAVVLGDNEFVSNDKQSLDKLVSDFKNNNMPLVSAN
                     IYEQSGENYVQPYVMKNIKTDEGNVKVGILGLTIKEVGETLGLEDFEKDKKARELGEQ
                     ADYKGKLYANDLVEDAKKWIKVMEKESPDIIVAVVHSGEEPKTDRNPGNRIKELATTV
                     DGIDAIVAGHTHEKIDEHKYKNKSGDEVIVTQPGWHGDRVSEINFKLNKENGKWDIKE
                     KSSKLKIIDKEVSIVATADLHSHFSDKLTVDLVNERSNPIEPVVVDAGDFLDPQTDEM
                     TQWYKEWKSIRDNNSDKTISRCPMVMDMNQGMYDAVVLGNHEFVSEKDEFWSDERLLD
                     AVIEDFEQVAISVLSANIYRQSGKNYVKPYIIKDVETSEGNVKVGILGLTIKEVGKGL
                     KNVNLQEQFQYKDKLYANDLVEDAKKWVKVMKKKKPDIIVAVVHSGEEPKNPKHPGNR
                     IKELATTVDGIDAIVASHTHEKIDEHEYKNKSGEKVIVTQPGEHGKYYSKITFKVNKE
                     KGSWTINDKFSKTIEVE"
     gene            19652..21556
                     /locus_tag="PC494_002593"
     CDS             19652..21556
                     /locus_tag="PC494_002593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HDF3913084.1"
                     /translation="MKIKFIIVASIIFLIVLLVGCQSTKDTEINVLATSDLHSIIPDN
                     LISYVEEERKYDENLLMVDAGDFFDMQSGEMNKWFTGQKLVRFKDGIPEYKKIAEPRE
                     GEVPLAKKMAKLKYDAVTFGNHEFVSNDKQSLDKLVSDFKNNNIPLVSANVYEQSGEN
                     YVKPYVMKNINTDKGTVKVGILGLTIKEVGERSRFKSFEQDKKARELGEQPQYKGKLY
                     ANDLVEDANKWVNVMEKKEKPDIIVAIVHSGEEPKNPKNPGNRIKELATTVEGIDAIV
                     AGHTHEKIEQHTYKNNSGEEVIVTQPGAHGNSISKINFKLDKKNDKWFIKDKYSELKV
                     FGKEVNIITTSGLNPKFSDEMAVNLFNERDRDVQPIFIDTGDFLNTNTKEMTKWAKEW
                     QYNENKGIYKKINEWPIVYLGYDAVVLGSHEFTEDKETFEEKKSTLDYIIENFEEMKI
                     PVLSANIYDESGENYVKPYIIHNVETREGNIKVGVLGLTTTDKDEEDLSNSSLSKDSK
                     TSKIPEETGKLYTNNLVKDASEWVKVMQKESPDVIVAVVHSDNNSTLKNPSSEVKKLA
                     MSVDGIDAIVVGHTKNKVEEHIYKNKSGDEVIVTQSGEDCYSKISLELRKENGKWNII
                     NKYSKAIKMK"
BASE COUNT         8123 a         2399 c         4071 g         7006 t
ORIGIN      
        1 aaatttttat attgaaatgt caaaataata aaagacctta taagttaatt acaggttaaa
       61 aaaataatat gtgaattttc tgatatttac taattatgaa taaaatattt aagtattaat
      121 gtttttagtg agactttaag acagataatc tcctattaaa gatactatat cttagataaa
      181 ataaattaaa acaatataaa aacataacaa gattacagaa agaaagctca caataaaatg
      241 ctgaaaaatt tattttaagg aggaataaag tatgaagttt caagaaatga ttaatagccc
      301 aggtctttgg attgtttcta gttttttagt aattatttca gttgttcaag caatcgtatt
      361 tatgaaagag gcactaaaag aggcttcaaa tcttggtatt gaaaggaaag gaattaaagc
      421 agcaattcgc tcagctagtg ttacagccat tggaccttct ctatctcctg ttattacatt
      481 attatcactg gtagctgtga ttggcgctcc tacgacttgg atgaggctct gtgatgtcgg
      541 agcagctaga acagagcttg gagtaatatc tcttacatcc aatttatctg gggtagaagt
      601 aggtagtgct gcatttggag cagaagcttt ttcgtatgca ctatggggga tggctttaaa
      661 taacttaggt tggctatttg ttgtatttat tttgggtcat agaatgcgtg gaattgttga
      721 aaagatgaac atgaagtata atcctacttg ggttaaaaaa ctacttgcag gagctacagt
      781 tggattattt gcttaccttc tttcaaatca aataaaaaca tttgaaatac caaaacttac
      841 accagcaatt atttcagcta tagttatgct agtattgaca actttattta aaaagaatca
      901 acgattacaa gaattatcct taggtattgc catgttaatt ggtatgtttg gtacacagat
      961 tatattattg tgattaaaac ggataagagg tgataattat gtatgataaa aagatgataa
     1021 aaatagggag aatttctata ggtcttgcaa ttattgcaaa ctttattccc gctatctatg
     1081 taggtattcg ctttggtcag atgccaatgc tttctgttat atttcaaatt tgggggttag
     1141 tcgctgcgac ttatggggtt agttggattg ttcaacctat agcttattat cctacactag
     1201 gagctccagg ttcttatata ggttggcttg caggttctgt tggagatata cgtatgcctg
     1261 cagcatcaat ggcacagaaa attgcaggtg tagaagcagg aactcatgag ggtgaagttg
     1321 ttggaacaat tggtacatgt tgttcaatct ttgtatcagc ttctatgatt accattttta
     1381 ccattgtagg ctataaagta attcctttgt tacctgaatt tgttactaat tcatttaatt
     1441 atatacttcc agcattattt ggagcaattt atgttgatat tgcacgtaag gatattcgag
     1501 ctggtggatg tacgattgct gtagcgttag caattatgta ctttggtgaa aaaattggta
     1561 taccaggtgg attattaaca ttgtttattg tgttaggtgg gatacttatc acaagggtct
     1621 tctttgtaat tgataacaat aaaacaaaag aataggattg cttattaagg agaaagacta
     1681 gaattatttg ttgagaaaaa agaataggat tgtttattaa gaaatatgaa tataaataag
     1741 tcttgaaagg agaaaaagca tgtttgatgt taaaattgtc aatggaataa tcgttgatgg
     1801 tacaggaaat tcaagatata aaagtgatgt agggattgta ggagacaaaa tcatggctat
     1861 tggagattta agtcaaaaag aggctaaaga gactatagac gcaactggaa aatttgtatc
     1921 acctggtttt atagatttcc atactcattc tgatttatct cttgtgtatg ataaatacac
     1981 aagaagccgt atccatacag gtgtaacaac agatgttatt gcaaactgtg gtataggagt
     2041 tgctccgata agagaagaga agaagcaaga gttaattgat tatcttggaa ctaggataat
     2101 tggtacaatt ccaacaaaat tagagcttca ttggaataca atgcaagaat actttgatta
     2161 cttaactgaa aattctccag cagtcaatgt tgtagcttat gtagcacaag gacctgtacg
     2221 tatcaatgaa atgggatttt caaaggaacc agctacttta gagcaactta aaaatatgaa
     2281 gttggaagtt agaaaagcta tggaagctgg atgtgtagct ctttcatcag gattagttta
     2341 tttaccagga gcatacacaa agaaagaaga aatggctgaa ttatgtaagg aattgatacc
     2401 atacaatgga tactatatat ctcatattag agatgaaggt gatgaagaaa tggaagctct
     2461 tgatgaagca atttatatag ctaagactgc aggagttcct ctacatgttt ctcatttaaa
     2521 agttatgggt cataagaatt ttggaactat tgatgaggta tttaaaaagc tagatgaagc
     2581 tgaggcagat ggtttggaag taacttttga ttgttaccca tatacagctg gaatgacatc
     2641 tttgggtgca cttttacctc cttgggcttt tgaaggcggt gtagaaaata tggtaaaacg
     2701 attagaagta caagaaaata gagacagaat tataaaagag ttggaggaag ggattcctgg
     2761 atggcaatgt ttctaccaat tagcaggtgg gtggaacggt gttgtactag cctctgtaat
     2821 gactgaagca aataaatatg tagagggtaa aactttaatg gaggtagcca aaatcaatgg
     2881 tgaaaatcca tttgatacgt tctttaggct tttgattgaa gaaaaaagta aaattcaagt
     2941 agttgttcat acacaaggtc aagaggatac agataaggtt gtttgccatc caaagtcatg
     3001 tataggttct gatagtatgg acctttctac agaaggttta ctttctcttg gaaagcctca
     3061 tcctcgtgca tttggtactt ttggacgaat tttctcttac tatgttagag aaaaaggtat
     3121 gttgactttt gaggaagcag ttaaaaagat aacttatctt tcagcaaaac gcttaggcat
     3181 ttataaagaa aggggtctac ttaaagaaaa ttattttgct gacattgtgg tatttgaccc
     3241 agatacaata gaagataaag cgacttatag taatcctaaa cagtatacag tgggagtgga
     3301 atatgtgttg gtgaatggta aaattgcatt ggcaggagga aagcaaactg atgtatgtgc
     3361 tggacgtgta attaaaaatc ctcttagcat agcaaaatag aatacattaa gaacttttat
     3421 aaaaatagtc tttctttgaa tattaaggaa ggctattttt gttaaattaa taaagattac
     3481 tctacttgtg ttttctaaag aatttaactt taagtagaaa aaacaatata ttaattgtaa
     3541 aatgtaatta atattaatga ataagattta aatacaaaaa tttaaataca aaaatgtttc
     3601 aacagatagt cgtaattaaa aaacttaaag taacttttta tattaggtat aattgattat
     3661 tcaaaattct atgaatcagg agtcctgtgg ctttagtcat ggtaggttta gaaaatgttt
     3721 taagagataa tagtatcatt aggaaaggag agacgaaatg aaaatacttt atgtaggacc
     3781 aggtatggta atcgataaaa tactagcagt aagtaaaaag aattttccta atattgaagc
     3841 agattttctt agatatgata gatatattga agtacctgat ttattggaaa aatatagagg
     3901 tagagtggat gcagttcttt ttacaggtaa gtcgccattt aaattttttg aaaaaagaca
     3961 aaaagatttt gtattgtctg attatattcc tagacatgaa acaacattgt acagagtgtt
     4021 gcttgaaatt acatatttgc ttaaattaga tattagtaga cttagtatag atacttatga
     4081 taaggctatg atgaagagat tgtataaaga aattggagtt gaatttaagg atgaacatat
     4141 gttttttgca gagcaaaagt atttagaaga ggactatata aagtttgtgc ttgaatttca
     4201 taaatataat tatcaaaata atgatgtatg ttgttgtatt acaggtcttg aagaggccta
     4261 tcatataatg aaaaaagata atattccagt agttttagcc ttgccttctg aggacgtaat
     4321 ggtgcaaagt ataaaaaaca ttcagatgcg ttatattgca aagaaaaaca atgagaatca
     4381 gattgttgtt cttgctatta aactgaacat gccttcagaa tattcactaa tgaaggaaga
     4441 tgagtacgct tatctttcac aaaggattaa gattcttgat aaactatacc atttcaatag
     4501 ccgtatagat ggtgttttgg tagagcagag tagaagtgaa tttatgattt ttacaactaa
     4561 aaaaatactt gagttagaaa caaagaaata cagagatatt tatttgttgg atatgattcg
     4621 tgaagtttca gttataaaca cttatatagg aattggttat ggaaaaacag caaatgaagc
     4681 taaatttaac gcttatgaga gtattaagat ggctcaaagt caaaaaaatg atgcagcata
     4741 tgtagttttt gaaaatggag aaattatggg accactaaag ccaaatccta ctgtcaaaga
     4801 gaaaaatagt tttgatgaac gtttttatca aattgctaca gagacagggc taagtgctaa
     4861 tactgtatat aaagtattca ataaaataat aaatagtgga aaaactgaat ttacatcaaa
     4921 ggaattagct actatatgtg gtgtaagtat tagaactatg gacaggatta tacttagatt
     4981 gtgtgattct ggttattgtg aggtagtgag tgaacagctt atgagcaagt atggtagacc
     5041 cagtagaata ttacgtttta aaccttttct gttgttttaa atagatataa gtcaaaaatt
     5101 aaatttttat gataacattt tctttacaat tttttagata tatgttaata tttagaaaaa
     5161 tgcatatgta ttcataaaat aaacttaaaa cagctgaaaa atcattaaaa aggaaatcgt
     5221 atgcatgaaa tgagaaagtt aatttataac ttaaataaat ctgggaggag ataattatgg
     5281 gaaaatatca gtattcaaaa aaagttgtaa gaaattattt tgaagcatta gaaaatgcta
     5341 ctggggatga ggttgaaaat gtcttaaagc aacatatgaa atcagattat aactggaaag
     5401 gtgtgtatcc atttcgtgaa caagaaggca ctgaaaatgt agcagatgta ttttggaagc
     5461 ctttaaaaaa atcattgagt aatatgcaaa gacgacaaga tattttcatt gcaggaacaa
     5521 atgagattga caatagtgaa tgggtaatga gtatggggca ttttatggga ctttttgata
     5581 acgattggct tggcattaaa catactcgta aaatgattag tttaagatat gcagaattta
     5641 actgtgttca agatggtaaa attgctaaaa ctggattatt tgtagatata attgggttta
     5701 tgattcaagc aggagttaat ccattgccac cacaaacagg ttcatatttt gtatatccag
     5761 ggccaattga ccataatgga ttactttttg aagatgcaga tgaagttgaa ggagtaaaaa
     5821 ctttagcatt agtaaataaa atggtagatg atttatctga attaaatgaa agtggtgcta
     5881 tgggatgccc accagaaata cttgaaaaat cttgggctaa agatatgatt tggtatggtc
     5941 caggtggaat tggtgcttct tatactatac ctagatatca agagcaacac cagctaccat
     6001 ttagaaataa tttaaaagga aagactttca atgggcatgt atgtagattt gcagaaggta
     6061 attttgcttg tttctttgga tggcctaatc tgactaatgt accatgtgga ggttttttag
     6121 gattaccagg tggagaggtt aaagcagata tgcaagttgt tgatgtttat tatcgtaagg
     6181 gcgataaact tcaagaaaac tgggtgttaa ttgatattcc ttattggttg aaacaacaag
     6241 ggcttgatat tcttgagaga actaaaagta tttttaatgc ttagttatgc atacgtattc
     6301 taaaacaaag ggggatataa agtggcatct accaacaaaa ataatgcaac aagtaaagag
     6361 gaagaaaaag aagtttctac aagtgtgctt gaatcatgta cggttaaaga aaaaaaagct
     6421 aaaatgaatc aaactaattt tagtaatata aatgaaaatc aaacaaatga gaataaaacg
     6481 aacacatata aaggaaatat agataaagga aatatagata aaacaaacac aaataaatcc
     6541 gacataaata aagttaacat agatacagtg gatacagata aattaaatac aaatactctt
     6601 actgaaaaaa ataaaaaagt tatatttaag ggggaagata atatgtcatc tacaaaaatt
     6661 tactatggag attcattaga agtaacgcct gttggagtaa tggattacaa tgatttttca
     6721 aaacagacaa aaagggaaca ggaaatacct ggatttgatt ctaagtatag agattttgta
     6781 gattatatta tgaagattac acataatatc tgggaagaaa aaggtatagg tgttatttat
     6841 gatacatatc acaataatgt tacaatgcat tgtggctctt caaatttagt tggtattaaa
     6901 gatgttattt ccaatactct tcaaacatta catgcgtttc ctgatagaag attaattggt
     6961 caaaatgtaa tatggtctaa ctttggtgct gatggttttt tatcttctca ccgtgttttg
     7021 tctacagcaa ctaacttagg tgatagtaat tttggaccag caacaggtag aaaaataaac
     7081 tttagaactg taattgattg tgccacaact aacaatagaa tccacgaaga atggttggtt
     7141 agagataatt tatggattgt tactcaatta ggattaaacc ctcaggaagt agcaaagagt
     7201 atggcaaagg caagtgaatc taaagtgctt agtttacaat caacttatgg tatctgtgaa
     7261 tctatggatg gtcaatttat gccaactaag tatcaagcaa aagatgattc tgttggcgaa
     7321 atgatgcttg aaatgacaag ccgtatttat aattataaat atataaatga agttaaaaaa
     7381 tactatcatg ataatgcagt agtacatttt atatgtgata aagatttaaa tggctatgat
     7441 gagattcaag gaatgattgt aagtttactt gcatcaattc caaatggaag ttatgaagtg
     7501 gaaagagtaa cttgtaatca aagagaaaaa aatgaaggtt atgatgtatc tgtaagatgg
     7561 agattacgtg gaataaatga aggtatagga ttttttggac agccttctgg aaagcatata
     7621 gaagtaatgg gaatcaatca ttatcatata ctacaaggta aagtaaagga ggagtggata
     7681 acttttgatg gtatggatgt attaaaacaa atgtatatgg gagtagaaga ataaagctgt
     7741 ttagagtata aatagttttg aaatgtatat agggaagtat tgctttataa aatttaagtg
     7801 gggaatgtat atgaaaaata gatgtttaaa cttttagcaa aattatgact aaatttaaaa
     7861 gggggaatta taaaaatatg aaaacaacgg ttgaaataga aaatgatatc atattaggaa
     7921 aagactattc aaacctaaaa agaggaattg catttttttc aattgcttta atatactttt
     7981 tttattgcta caattttatg gtgggtactt ttattaaacc aacaatgatt tatgctttag
     8041 cagatggggg atttggtttt tcattaaaac aaacagaaga aatatttgca gttatgtctt
     8101 ttggtacaat tccaggtaca tttatttttg gggtgatttc tacaaaaatt gggaagaaga
     8161 ggactttaat tagcgttgct ttactgattg gattgacaac atttatacca atgttatctc
     8221 ctaccaatat tatgttatgg aaaatagcac gtttgtgtac aggagtagtg ttgggaggcg
     8281 tatttggaac agctatgcct ttagttgcag atatgtttcc aagtaaatat cgtggtaagt
     8341 tagctgctat attaactgct ttattttcat tagcaatgat ttttggtggg aaagtatatg
     8401 gcgttttagg tgatgcaaat tggcaaatat tgatgtatac tgcgattata ccacctatag
     8461 ttggagctat cttagcaatc ttctttgtgc cagatgattt ggagtataca aaggaattag
     8521 ttaaaaaggg aaaagaaact ggtgaaaaga ttagctatat aagtatgtat aagggaaaat
     8581 acttatggat tggattggga acgattcttt tatcaggtgc aaattttaca gcatattcag
     8641 cattttcaaa taatgcaact acatacctag tgacaggaat aggaatgtca gcagcagtgg
     8701 ctgggtctat atatagttta caaggaattg gtcaattagt aggatattta ttctggggtt
     8761 caattgcaga taaatttgga agaaaaatac cttttatagg tatggcatta gcagcagtat
     8821 ttgtttttat atatacaaaa ttaggtggag ataatacaac aacattctat atgatatcag
     8881 tattactagg tgttgctgtt ggatattctg gagcatgggg agcatactac acagagttgt
     8941 tcccaagtaa atatcgttcg ttgtcatctg gtatgtcatt taatggagga aggattatat
     9001 ctacgtttgc aatacctgct atagctggta cagcttctgg tactttaggt atgatgacta
     9061 tcttttacat atcaatcgca gtctttgtag caggtgctat tgtatggtta ttcttaccgg
     9121 agacgttaaa taataaaaaa taaaatacta ggaatttatt ttgttactta gaaaggggtg
     9181 gcttatgatt tcatcaattg atgtatgtat tataatagga tatttgctat taatgttagt
     9241 tattggttat tattcaggaa aagataataa aaatcaagaa gattatttct tggcaggtag
     9301 gtcaatgcca tggattccaa ttgctttatc agttgcagct actatgatta gtgcaaatgg
     9361 ctttataggt ggtcctggat gggcatatgt agatggaatg tatccagtaa tggttaatat
     9421 tacagtacct ttagcaatat tttttgcact gagcattacc accccagtta tctataaatt
     9481 aaaaataacc tctatatatg aatatatggg acttcgttta ggaaattatt caagaggatt
     9541 aactattatt caatttttta ttaattcatt gattcaagct agttctatgg tatatattcc
     9601 agtgcttatt attcaaatga ttactggctg gtcactttat gctttagtcc caatagttgt
     9661 acttgtatca attatataca ctctattagg tgggattaag gcagttatat ggactgatag
     9721 tattcaaatg atagtagtaa taagtgctgt atttatagta attattgtag ccttaaaagg
     9781 aatgaatcta agtttctttg atacattaca aattgcacaa cagagtggaa aattaaatac
     9841 atttgatttc agtagggata tttcagtgac aaatactttt tgggctactt taattggtgg
     9901 aactgtaatg tggataagat acttttgttt tgaccaatct caagtacaaa gagttttaac
     9961 atctaaatct ttaaaatgtg caaaaaattc ttttgtagtt agtgcatttg ttatgaattt
    10021 agtttactac tttatgctat tggtaggagt aattttattt gttttttatg ggggaaggac
    10081 atttgaaact tcaaatgaaa taatgattac ttttatttta aatgaacttc cagtaggagc
    10141 cattggaatt attattgcag gtgtgtttgc agcagcaatg tctagtatcg actctatatt
    10201 aaacagtatg acaactgttt ttacgaagga tatttatgag ttttatttca aaaaagataa
    10261 caaagaatca tcattaaaag ttacaatgat tataactgta gttataggag ttgttatgac
    10321 aggttttatt attatgggat ttggaggaag catcaaatca attcttgacc ttgttggtaa
    10381 ctatatctca tactttgctg gaccagctac aggtgcattt gtactagcaa tgtttacata
    10441 taaagctaat gataaaggag tatctattgg ttttattgta gggttagttt taggattttt
    10501 tatttctaat aaatataatg tgagttggtt gtggaatcca gcaataggtg ctacaataac
    10561 attgatattt ggatatattt ttagtgtcat tttaaagaaa aatcataatg cagatgatat
    10621 taaaaaatac actgcatttg gtatgagaaa tcaccttatt tctcaaggaa tggataaagt
    10681 agatggagta tctatagtgc cattttcttt aggtaaacaa gaattaattg tattagcttt
    10741 ttttattatc caatatatta tattattttt gatacaattt taagaagaaa tactagatat
    10801 ttaaggagaa atactaaatg aatcaaaaga aagttcatta taataaatcg gctacctcaa
    10861 aagatgttgc aagattggca ggagtatctc aatcatctgt ttcaagagca tttggtagtg
    10921 caaatggaaa gggcgtaaaa cctgaagtaa gagaaagaat ttttcgtgta gcaaatgaaa
    10981 taggatatgt tcctaatttg gtagcacggg gaatgattag tggaaaaact aatgttatag
    11041 gattgatagt tggtgatagt ctaggtccat tttacaatag aattatcaat ttatttgtag
    11101 aaaaaattca agagataggt aaacagtgtc tcgtttttaa agttcctaga caacaaagta
    11161 tagatagtat aatttcaaaa gtaattcagt ttcaagtaga agctgtgatt attacagctt
    11221 cggccatgaa taaggtgatg gctgagactt gtgaagaaaa caatattcct gtgattcttt
    11281 ttaatcgttt tatacctggt ataaaaataa gtacagtcta tgtagaccca attgaaggtg
    11341 ggggaatggc tgctgaatat ctgcttaaga aaggtcataa gaatatagga tatattcaat
    11401 ttacgagaga aacaagtgaa gaaatggaaa agaaaattgg attttactct aagttaagac
    11461 aaagtgggat tcataacctt aaagaagaat ctgcaaacta tgattatgat tctggatatg
    11521 aagcaggtaa gagaatgtta gcattatcaa atcctccaac agcaattttt tgcacaagtg
    11581 acttgatagc tattggtgta atggatgctg caaggtttga gtacaagttg agggtgccag
    11641 aggatttatc agtgatagga tatgatgata ttcaaatggc ttcatggaag agttataatt
    11701 taacgacgat tagacagcca ctagatttgt tgattgaaaa aacaattaac atacttaagt
    11761 ccttattaaa tgaagaaaat ccagagtcag tcgttgaaat gttaaaacct gaattgattg
    11821 aaagaggttc tacactttaa gtggtagata tttaattaag tggtagatat ttaattaaat
    11881 ggcagatatt taatcaagtg atagatacct aattaagtga tagatattta atcaagtgat
    11941 agatacctaa ttaagttgta gatatctgat aagaaatttt taagttttca atcgttctaa
    12001 attgtgagta taaaaatcta ctaaatttag ttatgtaaaa tataaattat aagtgtagaa
    12061 actaggctac tagcttttat accacttcaa acattactgg aggtagttaa gtttacagca
    12121 gtttagtttt atgtagatat aatattctgt aaatagacaa aattaaaata tgtaattaaa
    12181 atatgtaagt gtctcaaaat gaaattttta gtttatgagg cacttttttg tataaaatca
    12241 aatgtatttt tataacttta acaataaaaa gaggcttatc tctattttga gacagcctca
    12301 aatttttaaa actatattag tttacagctt cttttcctat caaatctttt aactcttcat
    12361 gagtcatagt ttctttttca aataagaatt tagaaacaga atgtaaatct tcaagattat
    12421 cctttaacat ctctaaagtc tctttataac aaatttcaac tatacgattt gcttcctttt
    12481 gaaccttatc acataagaaa gtcttatcat ttccatcaat agtcataaat cctaagttac
    12541 tcataccata ttcacaaacc atttggttag ctatttcagt gactttcttt aagtcgtcct
    12601 ttgcaccagt agatttatga ttaaatatta attcttctga agcctttcca gcaagtaata
    12661 tttttatttt tccaatcaac tcatccttag tataaatata tctatcttca tcaggtaatt
    12721 gaagaacata acctaatgct tgtcctctag gaactataga tattttttgt ataggacaaa
    12781 ttcctactat atcacttaca agagcatgtc cagcttcatg atatgctact atttttttct
    12841 ctttttcaac caatgcagag tttttagatt ctagccctgc aataactctt tcaagtgcct
    12901 tgtcaaaatg ttctgatgta atacactcac tgtcatctct aactgcaaat atagctgctt
    12961 catttgctat atttgaaaga tgagccccat tgaaaccatg agttttttta gctaaaagtt
    13021 ctagatttac agatttgtct ataggtttgt catctgtatg tacctttaga atttcaaatc
    13081 tagtgtgata gtttggtgca cctatatgaa tgtgtctgtc aaatcttcct ggtctaagta
    13141 aagcttcatc taataagtca agtctattgg tagcacctat tattaataca ttggaatctt
    13201 tattaaatcc atccatttca actaaaagtt ggtttagtgt ttggtctttt tcgttgttac
    13261 tttcaagatg tctctttgct cctacagcat ctatttcgtc tataaatatt atacttggag
    13321 cttcttttct agctttttca aatagagttc taactctttt tgctcccaca cctacatatt
    13381 tttcaacgaa ctctgaacca gtaacattga aaaatgatga gtttgtttca ccagctacag
    13441 cagatgcaag tagggtttta cctgttcctg gaggaccata aaataatact cctttaggta
    13501 tttttgcacc cattttttga tatttttgtg gtgacttcat aaaatcgact atttcaaata
    13561 gttcttcttt tacttcgtct aatccagcaa cgtctctaaa tgtagtcttt ggttttgtag
    13621 aaagtgaatc atctgtttga ttatctcttt ccatttttgt ctgtgcaaag acaggagctg
    13681 gattgttgat tttcttaaaa aagttgttta gcattttcat attcacacct caggtaatta
    13741 attattgtta atcaatttta tattttccat atttactatt ttttattatt tatttttcat
    13801 ggaaaaaata tacatgttat ctaaataaaa ataaatttgt aagatgtatg aaaaaatgaa
    13861 tttatgtata tagagatttc tacttatgta ttgaataaag tattacaaat tataaattat
    13921 gtattgatta tatattgagt aaagtattat aaagcatgta ttgattaagt atttattaag
    13981 tattgaataa aatattacaa atttagttga aatgaaaatg ataaaaaatg ttgtactata
    14041 ttttacaaat catataaata gagaaattgt tgtagcgcaa agtagtaggt agtatattag
    14101 aatataatta taggatttgt tgtgtagtat agtagcatat tagaatataa tataggattt
    14161 gttatgtagt atagtagcat attagaatat aatataggat ttgttatgta gtatagtagc
    14221 atattagaat ataatatagg atttgttatg tagtatagta gcatattaga atataatgta
    14281 ggacttgtta tgtagtatag taacatatta gaatataatg taggatttgt tatgtagtat
    14341 agtagcatat tagaatataa tgtaggactt gttatgtagt atagtaacat attagaatat
    14401 aatgtaggat ttgttatgta gtataatagt atattagagt acaatataga atttgttatg
    14461 tagtatagta gtatattaga atacaatata gaatttgttg ggtagtatag tgttatatta
    14521 gaatacaata taggatttgt tatgtagaat atatagagtc atgtagaata tacatatata
    14581 aaaggatttt gggtataaat ttaaaaatta atagcaaaat gagtagtata gacatataat
    14641 tagtagtagg aagtaattaa atttttccta aacaaaaaaa atagttgcaa ataatttgat
    14701 taagtgatat agtaaataag gtaagaataa aacaaagaag aagtccgctt ctcaccttac
    14761 gccggaggtt agtaaggtaa atataagtta aagcttaatt ttaatttaag tttgtttaaa
    14821 tttggtaact tatattgcgg atgattacgt catccgcttt ttattttata aaaattttgg
    14881 aggtgtccta caattagcaa agaattagca atcaatgaac aaataaaaga taaggaaata
    14941 agagtccttt caccaacagg tgaacaactt ggagtaatgc ctactaaaga agctcaagca
    15001 atggctaata gcaaaaactt agatttggtt caaatctcgc cgaatgcaaa tccaccagta
    15061 tgtaagataa tggattatgg aaagtttaga tatgagcaag cgagaaaaga gaaagaagct
    15121 aagaaaaaac aaaaaactat agttgtaaaa gaagtaagac ttagaccagg tattgaacaa
    15181 aatgatttaa atacgaaagc taataatgct ataaagttcc ttaaaaaagg ggataaagtc
    15241 aaagttgaac ttagatttag aggaagagaa ttaggacata aagacatagg taaagaagtt
    15301 atgcttaagt ttttagatat aataaaagag tttggagaac caacaaaagc ccctgcattt
    15361 gagggtaata atatggttgt aattatagat ccaaaaaaat agatgattaa ctgagaggag
    15421 gaatttgtca tgcctaaaat gaaaactcat agaggtgcag caaagagatt aaagaaaaca
    15481 ggaactggaa agttaaagag agctaaagct tttaaaaaac atatattaac taaaaaatct
    15541 gcaaaaacta aaatgaactt aagaaaatca actttagtaa gtgatggaga tgctaagaga
    15601 atagcacaat tattaccata ctaagataca gattgtaaat aataactata gaagagggat
    15661 ataaaaggag gtcataacga tggcaagagt taaaaaagct atgaacgctc gtaaaaagca
    15721 taagaaaata ttaaaacttg caaaaggatt cagaggatct agaagcaaat tatatagacc
    15781 agcaaataca ttcgtaatga aagcattaaa aaatgcttat ataggaagaa agttaaagaa
    15841 gagagacttc agaaaacttt ggatacaaag aataaatgca gctgctagaa tgaatggaat
    15901 atcttattca agattaatga atggattaaa attatctggt gttgaagtta acagaaaaat
    15961 gttatctgaa atggctatac aagacccaga aggatttgca aaattagcag aagttgctaa
    16021 agcaaaatta gcttagtatt gaatcatgag atgtaaagtc tttgagttat ataaataatt
    16081 caaggacttt tttatttttt gaaaaatact tattagtgtc atgtacaacc aattttataa
    16141 tgataaataa aataagcaat acaatagaat tttatgagat ttattataag aattgttaca
    16201 attatttatg atagctataa aaagtcatag taaaaatgat attgatgtat gttgatatat
    16261 gtataaagtt tccaatcaat cttgaattaa tattatcaac atgataatat tatcttatta
    16321 ataatataaa taagggggac ataatatgaa tgaaaaacta atggattgtt ttgtaaaccc
    16381 aattaaatgc aagttattga ttgaaatttt ttcaaataat cgaactacag ctaaacaatt
    16441 aggagaaaaa tttcaagata tatcaaaggc aacactttat cgttacctta ataaaatgtt
    16501 gaaagatgat attataaaag tggttgaaga aaataaaata aggggaactg ttgaaaaagt
    16561 atatgctatg aagttagata tagctgatga tgtgaacaaa attatagatg agaactctgg
    16621 agaagaatat gctcaactgt ttactcaata tatgatggga tttttaagag aattttatga
    16681 atacgctgaa agaaaggaaa aggatatcct aaaagatggt tcaggatttt ctgtctgtcc
    16741 agtatatgct agtattgatg agatagttga agtgagtaaa aaaattgcta gtatactaga
    16801 acctctaaga aataactcac atgaagaagg tagaagaatg cattctatag gagtgataat
    16861 tactccacct aaaaaggatg aagggaaata aatctgattt acatggggta gagccaattt
    16921 atacagggaa tcgttttatg atttacatat gtatccagag caaagtatct ctgcttggat
    16981 tgtacttcat tgtaccattt catccaatga cttggagtgg tacaatgaag ttttttaatt
    17041 tttcatatta atgctaaaga aatgaacttt agaccacata tgcaattagg ttgcattata
    17101 caattagacc acatatacaa aataaaaatc agtattttta tagcagataa attgactgtc
    17161 attcttctta aaaatcatct attagttatt gttagcatat tgaaagaaat tatagtaatc
    17221 tattgaataa atgaatattg cctataatca tataaactgc tatagtttaa aataaagcag
    17281 gacgttaaat tttatagtaa tctaaaaatt taagaggggg attttatgaa aataaaattt
    17341 gttattatgc cattggtgat atttttaatg gtattatttg tggggtgtca aagtacaaaa
    17401 gatacagaag ttaaagcaaa agatacagaa attaaaatat tagggacagg tgatttacat
    17461 tcaattttga cagactctat ggtttcgtat gtaaatgagg aaagggaaaa gaataaaaat
    17521 ctgcttatgg tagatgcggg agatttctat ggtacacaaa gtagagaaat gtgggaatgg
    17581 tcttctggaa aaaagttaat taatattaaa agaaatggta gagcagagta tgatgacata
    17641 attaagagta gtaaagatga agtacctata gttaaagata tggcaaagtt gaaatatgat
    17701 gctgtagttt tgggagataa tgaatttgtt tcaaatgata agcaaagtct tgataaactg
    17761 gtttctgatt ttaaaaataa taatatgcca ttggtatcag caaatatata tgaacaatct
    17821 ggagaaaatt atgtacaacc atatgtaatg aaaaatatta agacagatga gggcaatgta
    17881 aaagttggaa tactaggtct tactataaaa gaagtagggg aaacccttgg tcttgaggat
    17941 tttgaaaagg ataaaaaagc tagagagctt ggagaacaag ctgattacaa aggaaaatta
    18001 tatgcaaatg atttagtaga agatgcaaaa aaatggataa aagttatgga aaaagaaagt
    18061 ccagacataa tagttgcagt tgtacactca ggggaagaac ctaaaacaga tagaaatcca
    18121 ggaaatagaa taaaagagtt agcaactaca gtggatggaa tagatgcaat tgtagctggt
    18181 catactcatg aaaaaataga tgaacacaaa tataaaaata aatctggaga tgaagtaatt
    18241 gttacacaac caggttggca tggagataga gtatcagaga ttaatttcaa actaaataaa
    18301 gagaatggaa agtgggacat aaaggaaaag tctagtaaat taaaaataat tgataaagaa
    18361 gtaagtatag ttgctactgc agatttacat tcacatttct ctgataaatt aacagttgac
    18421 cttgttaatg aacgaagtaa cccaattgaa cctgttgtag tagatgcagg cgacttctta
    18481 gaccctcaaa cagatgaaat gactcaatgg tataaagagt ggaaaagtat aagagataat
    18541 aatagtgata aaacgattag tagatgccca atggtcatgg atatgaatca gggaatgtat
    18601 gatgcagtag tacttggaaa tcatgaattt gtatctgaaa aagatgaatt ttggtcagat
    18661 gaacgccttt tagatgctgt tatagaggat tttgaacagg tggcaatttc tgtgttatcg
    18721 gcaaatatat ataggcaatc tggtaaaaat tatgttaaac catatattat aaaagatgtg
    18781 gagacgagtg aaggtaatgt aaaagtagga atattgggac ttactataaa agaagtaggt
    18841 aaaggtctta aaaatgtaaa cttacaagag caatttcaat ataaggataa attgtatgca
    18901 aatgatttag tggaagatgc aaagaaatgg gtaaaagtta tgaaaaagaa aaaaccagat
    18961 ataatagttg cagttgtaca ttcaggagaa gaaccaaaaa atccaaaaca tccaggaaat
    19021 agaataaaag aactagcaac tacagtagat ggtattgatg caattgttgc tagtcatact
    19081 catgaaaaaa tagatgagca tgaatataaa aataagtctg gagaaaaagt tatagtgaca
    19141 caaccaggtg agcatggtaa atattattct aaaattacct ttaaagtaaa taaagaaaag
    19201 ggttcgtgga ctattaatga taaattcagt aaaacaattg aggttgaata actttataaa
    19261 atttatagat aaagtaaatt atctgatatt ggcatgatat ataagataaa gtttctaata
    19321 ttagtataat gcataatgtg aaatatttta ataataagag aataaacaag acaaataaaa
    19381 atattttaac atgtaagata tagtatgaac tattatacta atgcttactt tataatttga
    19441 acatgttaga ataagtctta tttgaaaatt ttagtgtact agagtaagta ttattttact
    19501 agtaaaaaat attgagaact atatgtagat ttgcttaaaa aggaatttac atatagttct
    19561 tttcgtataa taaatagtac aatcttatat ggtaaagata aagtgtgata ttaaatttta
    19621 ttatcatcca aaatctaagg aggagtctct tatgaaaata aaatttatta tagtagcatc
    19681 aataatattt ttaatagtat tacttgtggg gtgtcaaagt actaaagaca cagaaatcaa
    19741 tgtactcgcc acaagtgatt tacattcaat tattccagat aatttaattt cctatgtaga
    19801 agaggagaga aaatatgatg agaatctact tatggtagat gcaggagatt tttttgacat
    19861 gcaaagtggt gagatgaata agtggtttac tggtcaaaaa ttagtaagat ttaaagatgg
    19921 gataccagag tacaaaaaaa tagctgaacc acgtgaagga gaagttccat tggctaaaaa
    19981 aatggcaaag ctgaagtatg atgcagttac atttgggaat catgaatttg tatctaatga
    20041 caagcagagc cttgataaat tggtttctga ttttaaaaat aacaatatac cattagtatc
    20101 agcaaacgta tatgaacaat ctggagaaaa ctacgtaaag ccatatgtaa tgaaaaatat
    20161 aaatactgac aagggaactg taaaggttgg tatacttggt ctgactataa aagaagtagg
    20221 ggaacgttca aggtttaaaa gttttgaaca agataaaaag gctagagaac ttggggaaca
    20281 acctcaatac aaagggaaat tatatgcaaa tgatttagta gaagatgcaa ataagtgggt
    20341 aaatgttatg gaaaaaaaag aaaagccaga tataatagtt gccattgtac attcaggtga
    20401 agagccaaaa aatcctaaaa atccaggaaa tagaataaaa gaactagcaa caactgtaga
    20461 gggaatagat gctattgtag caggtcatac acatgaaaaa atagaacagc atacatataa
    20521 aaataattct ggtgaagaag taatagtaac acagcctgga gctcatggta atagtatatc
    20581 aaagattaat tttaagttgg ataagaagaa tgataagtgg tttataaaag acaaatatag
    20641 tgaattaaag gtttttggaa aggaagtaaa tataattaca acttctggtc tgaatccaaa
    20701 attttcagat gaaatggcag ttaatttgtt taatgaaaga gatagagatg ttcaacctat
    20761 ctttatagat actggagatt ttttaaatac taatacaaaa gaaatgacta agtgggctaa
    20821 agagtggcaa tacaatgaaa ataaaggcat ctataaaaaa ataaatgaat ggccaattgt
    20881 atatcttggt tatgatgctg tagtacttgg tagccatgaa tttacagagg ataaagagac
    20941 ttttgaggaa aaaaaatcta cattggatta tattatagaa aactttgaag aaatgaagat
    21001 accagtatta tcagctaata tatatgatga atctggagaa aattatgtaa aaccttatat
    21061 aattcataat gtagaaacta gggaaggaaa tataaaggtt ggagtattag gtcttactac
    21121 tactgataag gatgaagaag acttaagtaa ctcaagctta agcaaagact caaagacttc
    21181 gaaaattcct gaagaaacag gaaagttata tactaataat ctagtaaaag atgcaagcga
    21241 atgggtaaaa gttatgcaaa aggaaagtcc tgatgtgatt gttgcagttg tacattcaga
    21301 taataatagt actctaaaaa atccaagtag tgaagtcaaa aaacttgcaa tgtcagtaga
    21361 tggaatagat gctattgttg taggtcatac gaaaaataag gtagaagaac atatttacaa
    21421 aaataagtct ggggatgagg ttatagtaac acaatctgga gaagattgtt attcaaaaat
    21481 aagtcttgaa ctaagaaaag aaaatggcaa gtggaatatc ataaacaaat atagtaaagc
    21541 aataaaaatg aagtgaattt attgatatat aaaccattat taacactgat ttttataat
//
LOCUS       DAMKNB010000063        20900 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.065, whole genome shotgun sequence.
ACCESSION   DAMKNB010000063 DAMKNB010000000
VERSION     DAMKNB010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 20900)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20900)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20900
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.065"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            314..703
                     /locus_tag="PC494_002594"
     CDS             314..703
                     /locus_tag="PC494_002594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HDF3913085.1"
                     /translation="MKINKLPHAELKLMKYIWGVDDVLASRDIIEDMKLKYDWKKSTT
                     LTFLKNLVDKGFLTTDKVDRCTHYTIAIKEKDYLKVETKSFFSFMHNNSFKSFISALH
                     DDEVLDSKSLDKLEEYFKNLKEEDIDD"
     gene            1023..1532
                     /gene="vanZ1"
                     /locus_tag="PC494_002595"
     CDS             1023..1532
                     /gene="vanZ1"
                     /locus_tag="PC494_002595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycopeptide resistance protein VanZ1"
                     /protein_id="HDF3913086.1"
                     /translation="MKSRKHNITKGLFIVYIIILTWIILFKLQFDISSLETMNLRSIN
                     LIPFAGSLIINNRVDISEIILNVAIFVPFGIYVCMLKEEWSFIKKVIPIFITSLVFET
                     LQYIFALGASDITDLIGNTLGGIIGIAVFMLLSKIFKNNTIKIINVLALIVTIIVVLF
                     LGLVIFANL"
     gene            complement(1634..1828)
                     /locus_tag="PC494_002596"
     CDS             complement(1634..1828)
                     /locus_tag="PC494_002596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase"
                     /protein_id="HDF3913087.1"
                     /translation="MSVIVMCSRCGKEIDKYRNKYITYYEKNTNAEIKVCINCALDLL
                     EKTRENQELNIQEFQDTIIL"
     gene            complement(2344..2736)
                     /locus_tag="PC494_002597"
     CDS             complement(2344..2736)
                     /locus_tag="PC494_002597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HDF3913088.1"
                     /translation="MAALKSFEKPLTPEEEIEYLTKFKIENDKSAKDTLIERNMRLVA
                     YIAKKYNNSTEDQDDLISIGTIGLIKAIETYNIDKGTRLATYASRCIENEILMNIRSN
                     KKNKTQVSLQDPIGTDKEGNEINTTLYM"
     gene            3303..3665
                     /locus_tag="PC494_002598"
     CDS             3303..3665
                     /locus_tag="PC494_002598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3913089.1"
                     /translation="MKIRKSGFISIECIISIAILYVAVYLVSTSLYNCYSFISRNISD
                     REMLSTAKKYIEDEKYRIQNSKYELIEDKIEKNYINGYEINSKIEQILDYYQCYEINI
                     EIKNEFKKLRFNSYVTRK"
     gene            3649..4374
                     /locus_tag="PC494_002599"
     CDS             3649..4374
                     /locus_tag="PC494_002599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3913090.1"
                     /translation="MLLENKGSILIITLIIFSIISTVCIMCIGLIYTHNNMFELGYKD
                     IQLKEISLSGIEISVSNVLSCVEEAIDVSNNEDEFREYFLGNNMIECIKKIKDTSYSS
                     LEELSLKVENNTIYDRGDFFEFDIESNVREKEFLKAIKVRVKIKNPWIGIDIEDYMDK
                     SNNNKIDDKTFNNYKASENNEILNQFKNESENIRNQEVGGFTEEDEEDEEYEEELKQN
                     IIENIKKNFDEKNLVQVYKYRGV"
     gene            4394..4813
                     /locus_tag="PC494_002600"
     CDS             4394..4813
                     /locus_tag="PC494_002600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3913091.1"
                     /translation="MTVIELIVSISIILLIVTLSFPKDNLENHKINLFARQLCSDIRY
                     VRRINMFSNYNTYIYYINQGKHEGYVLRKDGKNIKSIMLPKNAKIARSIEIIKFKSDG
                     SPQKASTIEIYNNRLRKTITITPVSGRVLLKEGKYET"
     gene            4803..5327
                     /locus_tag="PC494_002601"
     CDS             4803..5327
                     /locus_tag="PC494_002601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3913092.1"
                     /translation="MKHKYGYLLLESVVSLSSMVIIILVLYSIFLSTINLKLKVEDKI
                     ELQQQSLEIIKSMEGIISNSMGIMNVSNYEETFKKTTSIKCRYLDENNNEEGISNKEI
                     ILNERRNKLFVNSLNGESSQAGGYEIGDYVDEMYVSITNNGQYVNIKLKLSKRSQKYE
                     TDFKIKVWNFSESI"
     gene            5639..6196
                     /gene="efp"
                     /locus_tag="PC494_002602"
     CDS             5639..6196
                     /gene="efp"
                     /locus_tag="PC494_002602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HDF3913093.1"
                     /translation="MVSAGDFRKGVTFEKDGQPCLVVDFQHVKPGKGAAFVRTKYKNL
                     KTGAIREESFNPSEKFPKAVIDTRQMQYLYNDGELYYFMDQENFEQIPLNYEQVEDAI
                     KFLKENEVATIRFYQGQPFQVEAPNFAELEVTDTEPGIKGDTASNVTKAATVETGAVV
                     QVPLFINTGDKVKIDTRTGEYLSRV"
     gene            6288..6743
                     /locus_tag="PC494_002603"
     CDS             6288..6743
                     /locus_tag="PC494_002603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HDF3913094.1"
                     /translation="MKHLYEEVAYLKGLAEGLEISAESKEGKMIHKIVDALEVFADAI
                     VTLDEEQEELQDFVESIDEDLADLEEDIADMEEDLYEEDDDEDDEDFSYIEMECPNCG
                     ELVEIDEDLLYDDEVDVVCPDCKAVILSSEDDCDDDCTCGGCSSCDDRE"
     gene            6906..7616
                     /locus_tag="PC494_002604"
     CDS             6906..7616
                     /locus_tag="PC494_002604"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HDF3913095.1"
                     /translation="MKISKKLLDNIQRFENVINYKFKNKEYILEALTHSSYSNENKKY
                     NFNERLEFLGDSVLGIVISDYLFNEEANLPEGELTKLRANIVCEDSLSEVANDINLGI
                     HMLLGRGEEATGGRHRTSILADAFEAVIAAIYLDGGFESARQFILHHMENIIYDSRKG
                     NIFRDYKTHLQEVLQGNGENNIWYRLIEEKGPDHNKRFVMEVGINDDVLGIGEGKSKK
                     EAEQLAAKIALKKKLWEK"
     gene            7670..8740
                     /locus_tag="PC494_002605"
     CDS             7670..8740
                     /locus_tag="PC494_002605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HDF3913096.1"
                     /translation="MKKRIIPIFVPHKGCPHDCIFCNQKKITGVSTDVTSEDARNIIE
                     ECLETIDKDADVEIAFFGGSFTAIDIDIQKSLLSVAKEYVEKGLVKDIRMSTRPDCID
                     EDILSMLKEYKTSIIELGVQSLDEKVLLDSIRGHQSEIVYKSSKMIKNSGIKLGLQMM
                     IGLPADTEEKCIFTAKKFVELKPDCVRVYPTLVVKDTGLEKLMEQNKYNPFTLEESVN
                     IVKKVLVLFYVNNINVIRVGLQATDDIQIGKAVLAGPYHPAFRELVEADMIKDYLEFV
                     ILQNKNIKQMLVKSNKKNISKIIGNKKTNVKYMEEKFGVLLKTQESDLDINQLEIVLD
                     GKSLISANMRDIHRKLYDIYDL"
     gene            8768..12322
                     /gene="smc"
                     /locus_tag="PC494_002606"
     CDS             8768..12322
                     /gene="smc"
                     /locus_tag="PC494_002606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HDF3913097.1"
                     /translation="MYLKRLELKGFKSFPVKTDIIFKEGITAIVGPNGSGKSNISDAV
                     RWVLGEQSIKSLRGDKLEDVIFAGTDTKKPMNYCEVALTIDNSENQLELDFTEVTIRR
                     RAYRNGESEFFLNNKSCRLKDIKEVFLDTGIGKDGYSIIEQGKVDEILSNNPLSRRKV
                     FDEACGISKYRYKKQEAERNLSNTKENLERIDDVYIEIENQLKPLFNQQTKAKKYLEI
                     SEKLKTLEVNSFIREIEGIEKELSEVNEHRKVIEKELNEKEEQKNVVEKKQEDINKEV
                     EVLQDVIEKSVDYINSIKGVISKKESQINLIKERIRNFTNEISRKNLEIKDIKEKLNE
                     NKQYIKELESNKLSGSEELSTLQENIKVLEGSKDKQKIKLESLNNEIELLKESIIDIL
                     NKKQEFSNKLSTLNANKENMNIRDENINSEITELNKNIEIKSSELDTINKEFNMQNEN
                     LKNVNNRHKELSINLQDSISEHNKLEDEIQKSKYNLNGYNSKLNVYIDMENHYEGFNR
                     GVKEVLKNKNLKGVHGALGQIINVPEKYEKSIEAALGAYMQNIITDNEFSAKFAINYL
                     KQNNLGRVTFLPLNIIKSNKISLGNLKANTKFIGIASDLITFDEKYRNIIENILGRTI
                     LINNIDEGIKFAKETGHRFKIVTLDGEILNPGGSLTGGSLKTNGNILSRKRYINEYTE
                     KISNIKNEISHLELKRESLDKDVKNIKNEIDSHESKIKDLEKSIIIKSTSIKNVESEI
                     ESLKGSITKLENEKNDLNSNLNYTLEKSDDVRKDMEELDDLYNKNKEKIDALNEEIKR
                     YNDLYDKEKSEFDELNLSLVKKTEVYNSIVRDIKRISGENCELEEKNKQLEESLNYEE
                     HEIIKLQDSILTEEKEKENLTKQLGDSNRNLETRKIAKDDLKNSFDEINKELKTIDRQ
                     HIELKESLFKVGGRLERLKTSQDTYINKLFEQYDMTLVQALEIKDEDLDIDRKFLESL
                     KREIRSLGNINIDSIKEYEEIKERYDFYSEQKQDLEESMEEIEKLIHTLEENMKSEFE
                     IKFEEISKNFKYVYKRLFGGGCGELTILDKENLLESDILITAQPPGKKMKNLNLLSGG
                     EKALTAISILFAILITKPTPFCILDEIEAPLDDANIFRFGEFLKDLSKETQFISVTHR
                     RGTMEAADYIYGVTMQEKAISKVISLKLKEAQEITDII"
     gene            12349..13629
                     /gene="ftsY"
                     /locus_tag="PC494_002607"
     CDS             12349..13629
                     /gene="ftsY"
                     /locus_tag="PC494_002607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HDF3913098.1"
                     /translation="MLKKLFGFGKDKEKEIEKKDAEEEIEVEDSVDNLENLEETIFSG
                     LEEEVIDKVEDIEEKNEESVNNEGTEEIENFEKIEVEMDSNGKEVENISNNDSQEEII
                     EELENYDEIESKEIEDKEDKKVNLFERLKQGLTKAKQGITDRIDEVLKSYTKIDEELL
                     EDLEEILITADVGVNTTMDIIERLRDKIKQKGITEPIKVREELKSIVEDILTNENSTL
                     DIEPAPCIILMVGVNGVGKTTTIGKLANRYKKDGKKVLLAAADTFRAAATEQLEIWAN
                     RTNVDIIKHQEGADPGAVVFDAIKAAKARKTDVLICDTAGRLHNKANLMNELGKVFKI
                     VDREFPEAKREVLLVVDATTGQNAVVQAKTFKEVADITGIVLTKLDGTAKGGVVLAVK
                     SEVDVPVKLIGVGESVEDLQDFNAKSFSDALFGN"
     gene            13732..14100
                     /locus_tag="PC494_002608"
     CDS             13732..14100
                     /locus_tag="PC494_002608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HDF3913099.1"
                     /translation="MNIEKMVEIGLLFEQYKELLTDKQKEIVALYYEEDYSLGEISEN
                     LNVSRQGVYDTLKRSEKILRDYEEKLHLVSKIQEQEKNIKIIKDKIIDIKEDLLHNRD
                     CANLIPKLENIEDVCREMIK"
     gene            14097..15449
                     /gene="ffh"
                     /locus_tag="PC494_002609"
     CDS             14097..15449
                     /gene="ffh"
                     /locus_tag="PC494_002609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HDF3913100.1"
                     /translation="MIFEGLSDKLQGAFSKLKSKGKLTEVDVKNAMREVKLALLEADV
                     NFKVVKDFIKKVQERCVGQEVMQSLTPAQHVIKIVNEELTSLMGDVQSKVMISSKPPT
                     ILMMVGLQGAGKTTTAGKLGGYFKKQGKKPLLVACDIYRPAAIKQLQVVGEKLDIPVF
                     NMGDKENPINIAKAGLSHAIKNANDLVIIDTAGRLHIDEVLMDELKSIKSEVKPHEIL
                     LVVDSMTGQDAVNVAESFNEALGVDGVVLTKLDGDTRGGAALSIRAVTQKPIKFMGMG
                     EKLDDIEPFHPDRMASRILGMGDVLSLIEKAQENIDLEKAKELEQKIKKQELDFEDFL
                     QQMEQIQNMGPLDKILGMIPGMGNVKDQLGDVDLNGKEMKRTKAIIQSMTTYERRNPG
                     VLNASRKKRIAKGSGTSVQDVNRLIKQLNEMKKMMKMFAGSQKSMKKRGGLGGLPFFK
                     "
     gene            15487..15759
                     /gene="rpsP"
                     /locus_tag="PC494_002610"
     CDS             15487..15759
                     /gene="rpsP"
                     /locus_tag="PC494_002610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000268750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HDF3913101.1"
                     /translation="MAVKIRLKRMGANKKPFYRIVVADSRAPRDGKFIEEIGYYNPIS
                     EPKQVRINDEKAIKWLATGAQPTEVVKKLLVKNGVIEKFEASKQAK"
     gene            15824..16051
                     /locus_tag="PC494_002611"
     CDS             15824..16051
                     /locus_tag="PC494_002611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HDF3913102.1"
                     /translation="MKELVVDIAKALVDNPDSVVVEEFEDNDGIVLKLTVAQEDMGKV
                     IGKQGRIAKAIRTVVRSVANRENIKVSLEIV"
     gene            16159..16674
                     /gene="rimM"
                     /locus_tag="PC494_002612"
     CDS             16159..16674
                     /gene="rimM"
                     /locus_tag="PC494_002612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA processing protein RimM"
                     /protein_id="HDF3913103.1"
                     /translation="MKEKLTHFKVGQIVNTQGLKGEVRVYPLTDDIERFDELKDFYLG
                     KDLNNKLAVEKVRYKGSMVIMKIKGIDSIEKAEKLKNKFMYVAREDSRELEEGEFFIA
                     DMIGMEVLTVDGKYVGILEDVLQYSANDVYVVKGEEDKEFMIPAIKKFVPTIDIDERK
                     MIIDPIKGMID"
     gene            16683..17378
                     /gene="trmD"
                     /locus_tag="PC494_002613"
     CDS             16683..17378
                     /gene="trmD"
                     /locus_tag="PC494_002613"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000686892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HDF3913104.1"
                     /translation="MRFHIMTLFPEIFNSYMDESIMKRAVEKGIIEVHIYNIRDFSNN
                     KHKKVDDYPFGGGAGMVMTPQPIYDTYKHIITTHNINNPSVIYLTPKGKVYNQSMAKQ
                     MSLKEDIILLCGHYEGIDERIIDLIVTDEISIGDYVLTGGELPALIMIDSISRLIPGV
                     LNQEESFEEESFKDNLLEYPHYTRPRDFEGLKVPEVLLSGNHKKIDEWRREESIRITK
                     ERRFDLYKKSNEK"
     gene            17563..17913
                     /gene="rplS"
                     /locus_tag="PC494_002614"
     CDS             17563..17913
                     /gene="rplS"
                     /locus_tag="PC494_002614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HDF3913105.1"
                     /translation="MNEMLRAIEQEQLKNEVPNFGPGDTVKVHVRIIEGKRERIQVFE
                     GVVLKRQGGGARETFTVRKMSFNVGVERTFPVHSPKIEKIEVTRKGKVRRAKLNYLRG
                     RVGKAAKIKEARNK"
     gene            18234..19130
                     /gene="ylqF"
                     /locus_tag="PC494_002615"
     CDS             18234..19130
                     /gene="ylqF"
                     /locus_tag="PC494_002615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HDF3913106.1"
                     /translation="MSNEYEEYLMNDNLHINWYPGHMKKTKELVKNNLKLIDVVIELL
                     DARIPFSSKNPDIDRLVGDKPRVVVLNKSDMADRDKLNQWIEYYKKINIKAIPVDTIK
                     GVGINKIIEECKNVTREKMSSLKDKGRKERAIRIMIVGVPNVGKSSLINKLTGRKSTQ
                     TGDKPGVTKGKQWVRLKGNLELLDTPGILWPKFEDQEVALNLAFSRAIKDEILDTETL
                     ALRLIEKLMKIEPEKLKARYKLDCLGETPIETMDMIGHKRGFITGKKELDYTRIATTV
                     LNEFRDGKIGNITLEVPENVKR"
     gene            19519..20811
                     /gene="brnQ"
                     /locus_tag="PC494_002616"
     CDS             19519..20811
                     /gene="brnQ"
                     /locus_tag="PC494_002616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HDF3913107.1"
                     /translation="MGKTKDVIVFGFALFAMFFGAGNLIFPPYLGIITGPEWLIAFLG
                     FTFADAGLALLAVMATAKFDGNVVEMFKRCGMKLGILIGCADILCIGPFLAIPRTGAT
                     TYEMGIMPLFGTSIPVLLFCILFFAISYVLTIRPSKVVDIVGQFLTPALLIALAFIII
                     KGIISPLGDIVDKPMIPNVFAEGIGQGYQTMDAFAAIALASVLIVSLNDKGYSTISDK
                     LKMIGKAGVLACGGLALVYGGLCFLGATVSTMYGTDAVQSQVIVNITEGLLGNVGKAI
                     LAVVVSLACLTTSIGLTSATGQYFSRLTKGKLSYEKIVLAVSVFSAVVASFGVGTIIK
                     IASPILSIVYPPSIVLIILAFFNEKIKNDNVYKGAVYMSLLVSILTVISSYGVAVPVV
                     NSLPLNSLGFNWVVPVIIAGIIGNFIPSKSQSNTLGTN"
BASE COUNT         8782 a         1954 c         3753 g         6411 t
ORIGIN      
        1 aacttaatat aaattaagta tatgaaataa atatcctgta tttaagctta tagattataa
       61 tgaaatataa tacatgttgc aataataaaa cgaactaaaa ttatcacact aaagcataaa
      121 acatactcta atcatgttag ataaattttt gaatatataa tccaaaagta ctctctaaag
      181 tagagtactt cttttttatt aattattttt atatagaata aattggaatt tatatttatt
      241 ccaatctaat tgattacata cacttattgt tataaagttt agttatacat aaattggtaa
      301 gaggtgtaaa ctaatgaaga ttaataaatt accacatgca gaactaaaac taatgaagta
      361 tatttgggga gtagatgatg tattagcctc aagagatatc atagaagaca tgaagttgaa
      421 atacgattgg aaaaagagca caacattgac atttttaaaa aatttagtag ataagggctt
      481 tttaactact gataaggtag atagatgtac gcattatact atagctataa aagagaaaga
      541 ttacttaaaa gttgagacaa agagtttttt tagttttatg cataacaatt catttaagag
      601 ttttatttca gcactacatg atgatgaagt tttagatagt aagagcttgg acaaattaga
      661 agaatacttt aaaaatttga aagaagaaga tattgatgac taataaagct atcagtatct
      721 ttttagtttg agacaattga gagtagcgtt tggatttaat gttagtttta tgtgatggta
      781 gaacattata taaagaaaag tgattatttc cttagtgttt gatagtaaaa aatatagaga
      841 ataataccaa ttaaaattta aagatatatg aaatactaca atagcttaaa tcatgtaaat
      901 atgataaaga tattgaaatt ataaaaggaa tataatttta gaagaaatag ttgacagata
      961 aattacctta ctatattatt gtattaataa aataatacaa taatatagta aggaggtaat
     1021 aaatgaaatc tagaaaacat aatattacaa aaggattatt tatagtttac ataattattt
     1081 taacatggat aatactattt aagttgcaat ttgatatctc atctcttgaa accatgaatc
     1141 ttagaagcat aaacttaata ccttttgctg ggtcacttat aattaataat agagtagata
     1201 tatcagagat tatattaaat gtggctatat ttgtaccatt tgggatatat gtgtgtatgc
     1261 taaaagaaga atggagcttt ataaaaaaag ttatacctat ttttataact agtttggtat
     1321 ttgaaacact tcaatatata tttgcactag gtgcaagtga tataacggat ttgataggaa
     1381 acacactagg aggaatcata ggaatagctg tttttatgct attatcgaaa atatttaaga
     1441 ataataccat aaaaattatc aatgtattgg cattgattgt gacaattatt gttgtattat
     1501 ttttaggatt agttattttt gcaaacttat agaaataagt atatatgttt agcttaaaat
     1561 agaacgtaag atacagttac atataaaatt atttacacat aaaaagcacc tatacaggtg
     1621 ctttcctaaa ttattaaaga attattgtat cttgaaactc ttgtatgttc aattcttgat
     1681 tttctcttgt tttttctaat aaatctaacg cacaatttat acaaacttta atttctgcat
     1741 tggtattttt ctcataataa gttatatatt tatttctata tttatctatt tcttttccac
     1801 aacgactaca cattacaatt acgctcatat cttagttcct ccatctctaa ttattcttaa
     1861 tatattcaat agtatcactt ttctgaaaat aatgattgtt aaaactgtat caaatttaga
     1921 tttacttttt attataatgc attttaataa aaaaataaag gttatgggta aaatatttat
     1981 agaaaaaagt atattattga atagattata aaattttatt attttttagc agtgttaaat
     2041 acacattaat atctataaag tgacaaaata aaaaatacta tttaaataga tattaaaaaa
     2101 ttgataccaa gtatttattt gctatatgaa taacaattta tttaggaact ttactttaac
     2161 actgtataat aataaagtaa ttgctaaaaa cgtttgatga tttggatgta tttttagaaa
     2221 ttagaaaaat atatacttac tgactaatga taatcttata tgtattttag tttgagtgat
     2281 ttaagaaaag tgttttgaat ggggattatt ttatagagta aataaatata taatagtaga
     2341 aaattacata taaagagtag tgtttatttc attaccttct ttatctgttc cgatagggtc
     2401 ttgtagagat acttgagttt tatttttttt gttagatcta atattcatta aaatctcatt
     2461 ttcaatacat ctagaagcat atgttgctaa tcgagttcct ttatctatgt tataagtttc
     2521 tatagcttta attaatccta ttgtacctat ggatattaaa tcatcctgat cttccgttga
     2581 attattatat ttctttgcta tataagctac taatctcatg tttctttcaa ttaatgtatc
     2641 ttttgcactt ttatcgtttt ctattttaaa tttagttaaa tactcaatct cttcttcagg
     2701 ggttaagggt ttttcaaaag atttaagagc tgccaatagg tcaccccctt ttcaacggtc
     2761 actttaaatt atatgaagga gacttatcca agttgactgt tatctaataa aataatatgc
     2821 atatttttag aatttaaaac atatatttgc aaacttttga atggaatatg acataaagag
     2881 tgggaattta aatttaagtt tttgttgtat atatatgaaa taaggcgaag aaattattga
     2941 tttataaagt ataaattgga attgaggtgt caataaatat aaaaggaaat agtatttata
     3001 tatgttttgg tgttgaagta aaagattaat gcaaagcatt agagtctata aaaatatgaa
     3061 tataggaggt gtaattttac aatacttaaa aaagtaaatg taattaattg tttgtataaa
     3121 gttgattaca agcaaaagta tcagtcatag ttaatactgt taagggtgaa ggtggtgtgt
     3181 taatttatat atgtatggga agaaattttg attacaatga aaaaacttac aaaagatatt
     3241 tatgaaaaaa cttatagtta aatgtttata tataaaatat tatttagggg ttgtttttat
     3301 tattgaaaat aagaaagagt ggttttatat caattgaatg tataataagt attgctatat
     3361 tatatgtggc tgtttattta gtttctacat cattgtataa ttgttatagt tttatcagta
     3421 gaaatatatc tgacagagaa atgttaagta cagcaaaaaa atatatagaa gatgagaagt
     3481 atagaataca aaatagtaag tatgagttaa ttgaagataa gatagaaaaa aattacataa
     3541 atggatatga aattaacagt aaaatagagc aaattttaga ttattatcaa tgctatgaaa
     3601 taaatataga gataaaaaat gaatttaaaa aactgaggtt taatagctat gttactagaa
     3661 aataaaggct ctatattaat aataacattg ataatatttt ctattataag tactgtgtgc
     3721 attatgtgta taggtttaat ttatacacat aataatatgt ttgagttagg atacaaggac
     3781 attcaactaa aagaaatttc tttaagtgga atagaaatat cagtaagtaa tgtactttct
     3841 tgtgttgagg aagctattga tgtatctaat aatgaagacg aatttagaga atatttctta
     3901 ggaaataata tgattgaatg tataaaaaaa ataaaagata catcttatag tagtttagaa
     3961 gaactttctt taaaagtaga aaataatact atttatgaca gaggagattt ttttgaattt
     4021 gatatagaaa gtaatgttag agaaaaagaa tttttaaaag caataaaagt aagagtgaaa
     4081 atcaaaaatc catggatagg aattgacatt gaagattata tggataaatc taataacaat
     4141 aaaattgatg acaaaacatt caataattat aaagcatctg aaaataatga aattctaaat
     4201 caatttaaaa atgaaagtga aaatataagg aatcaagagg ttggtggatt tacagaagaa
     4261 gatgaagaag atgaagaata tgaagaagaa cttaaacaaa acataattga aaatataaag
     4321 aagaattttg atgaaaaaaa cctagtacag gtatataagt ataggggtgt ataactttga
     4381 aaaaagaagg aatgtgactg taatagaatt aatagtatct atcagtataa tactcttgat
     4441 agttacatta tcttttccaa aagataatct tgaaaatcat aaaataaatt tatttgcacg
     4501 tcaactttgt tcagatataa ggtatgttag gcgaattaat atgtttagca actacaatac
     4561 atatatatat tatataaatc aaggtaaaca cgaaggttat gtattgagaa aagatggtaa
     4621 aaacattaaa tcaataatgc tacctaaaaa tgcaaaaata gctaggagta ttgaaataat
     4681 aaagtttaaa tctgatgggt cgcctcaaaa ggcgtctaca atagagatat ataataatag
     4741 attaagaaaa actataacaa taacacctgt aagtggaaga gtacttctga aagagggaaa
     4801 atatgaaaca taaatatggt tacttgcttt tggaaagtgt cgtatcattg tcttcaatgg
     4861 tgataattat actagtttta tattctatat ttttgtctac aataaactta aagttaaaag
     4921 tagaagataa gatagaacta caacaacaaa gtcttgaaat cataaaatct atggaaggaa
     4981 ttattagcaa ttctatggga ataatgaatg tatctaatta tgaagaaaca tttaaaaaga
     5041 caacatctat aaaatgtaga tatttagatg aaaataataa tgaagaaggc ataagtaata
     5101 aagaaattat attgaatgaa agacgaaata agttatttgt aaattcttta aatggcgaaa
     5161 gtagtcaagc aggtggttat gaaattggag attatgtaga tgagatgtat gtatcaatta
     5221 ctaataatgg tcaatatgtt aatattaaat tgaaattatc aaaacgtagt caaaaatatg
     5281 agactgattt caaaataaaa gtatggaatt ttagtgaaag tatatagaaa tacataaatt
     5341 taagagaaag aagtgacatc aataagtcat ataaaatata attattgaga actatataac
     5401 taaataatat caatatgtaa agtgtataga ttaagaatat agaggataat aataaaaata
     5461 tagaataagt aatttgccaa atacttgttt atattgtata acttatgata ttatgatatt
     5521 agtaaaaatt tgtaatcctg acttgacaga attcaagtaa gagatataat tttaaaggca
     5581 tagtaatgta aaatttacta aaaaataaga aatttatttt aatatggagg aacaaaaaat
     5641 ggtatcagca ggtgatttta gaaaaggtgt tacatttgaa aaagatggac aaccatgttt
     5701 agtagttgat tttcaacacg ttaagccagg taaaggagct gctttcgtta gaactaaata
     5761 caaaaactta aaaacaggag ctataagaga agaaagtttc aatccaagtg aaaaattccc
     5821 taaagctgtt atagatacaa gacaaatgca atatctatac aatgatggtg agttatatta
     5881 ttttatggat caagaaaatt ttgaacaaat accattaaac tatgagcaag ttgaagatgc
     5941 aattaagttc ttaaaagaaa atgaagttgc tacaataaga ttttaccaag gacaaccatt
     6001 ccaagtggaa gcgccaaact ttgcagagct agaagttaca gatacagagc caggtataaa
     6061 aggtgataca gcaagtaatg taactaaagc agctacagtt gaaactggag cagttgttca
     6121 agttccatta tttataaata ctggagataa agtaaagata gatactagaa caggtgaata
     6181 tttatcaaga gtataaaaat ttatgtatat aaaagcttat atgtcttaat aatataagat
     6241 atatgagctt ttagtttata tataaaaaag aaagcgaggg gtgttacatg aaacatttat
     6301 atgaagaagt tgcatactta aaaggcctag cagaaggact agaaataagt gctgaaagta
     6361 aagaagggaa aatgatacat aaaatagttg atgcattaga agtatttgca gatgctattg
     6421 taacattgga tgaagaacaa gaagaacttc aagattttgt tgaatctata gatgaagatt
     6481 tagcagattt agaagaagat attgctgaca tggaagaaga tctttatgaa gaagatgacg
     6541 atgaggatga tgaggacttc agctatatag aaatggaatg cccaaattgt ggagagttag
     6601 tagaaataga cgaagatttg ttatatgatg atgaagtaga tgttgtttgt cctgattgta
     6661 aggctgtgat attatcatca gaagatgatt gtgatgatga ttgtacatgt ggtggttgtt
     6721 caagttgtga tgatagagag taaaaattca taagaattaa aactgcctat gatgcctatg
     6781 agatattttg cttcataggt agttttattt ttatgaggaa gggtattatg tattttggtt
     6841 ttgcaatact tggacaaaaa tagtacacta gaatttatag aataggattt tggagggatg
     6901 taaatatgaa aataagtaaa aaattactag ataatataca aagatttgaa aatgttataa
     6961 attataaatt taaaaataaa gaatatatac tagaagctct tactcatagt tcatattcta
     7021 atgaaaataa aaaatataat tttaacgaaa gattggaatt tttaggggat tcggttttag
     7081 gcatagtgat aagtgattat ttatttaatg aagaagctaa tctgcccgaa ggggaactaa
     7141 ctaaacttag agcaaatata gtttgtgaag attcattaag tgaagtagct aatgatataa
     7201 atttaggtat tcacatgtta ttaggtagag gagaagaagc aacaggagga agacatagga
     7261 cttcaatatt agcagacgca tttgaagctg taatagctgc tatatatctt gatggaggtt
     7321 ttgaaagtgc aagacagttt atacttcatc atatggaaaa tataatttat gattcaagaa
     7381 aaggaaatat atttagagac tacaaaacgc atcttcaaga ggtgttacaa gggaatggag
     7441 aaaataatat ctggtacagg cttatagaag aaaaaggacc agaccataat aaaagatttg
     7501 taatggaagt tggaattaat gacgatgtac ttggtatagg agaaggcaag agtaaaaaag
     7561 aagctgaaca gttagctgct aaaatagctt taaagaaaaa attatgggaa aaataaatat
     7621 aatatgtaaa aatataaaaa gaaatattta tattagaagg atgttgtaga tgaaaaagag
     7681 aattatacct atatttgttc ctcacaaagg atgtcctcat gattgcatat tttgtaatca
     7741 aaaaaaaata acaggtgtga gtactgatgt tactagtgaa gatgcaagaa atataattga
     7801 ggaatgttta gagactatag ataaagatgc agatgtagaa atagcatttt ttggtggtag
     7861 ctttactgct atagatattg atatacaaaa aagtttatta tcagttgcta aagaatatgt
     7921 agaaaaaggt cttgtaaaag atattagaat gtctacaaga ccagattgta ttgatgaaga
     7981 tatattaagt atgttaaaag aatataagac aagtataatt gaactaggag tacaatcctt
     8041 agatgaaaaa gtattattag atagtataag aggtcatcaa tctgaaattg tatacaagag
     8101 ttcaaagatg ataaaaaata gtggaatcaa acttggatta cagatgatga ttggtcttcc
     8161 agctgacaca gaagaaaagt gtatatttac agcaaaaaaa tttgtagagc taaaaccaga
     8221 ttgtgttaga gtctatccaa ctttggtagt aaaagataca ggtcttgaaa agttaatgga
     8281 acaaaataaa tataatccat ttactcttga agagagtgta aatatagtaa aaaaagttct
     8341 tgtactgttt tatgttaata atatcaatgt aataagagtt gggcttcaag ctactgatga
     8401 tatacaaatt ggaaaagctg ttttagcagg accatatcat cctgcattta gagagttggt
     8461 agaagcagat atgataaaag attatttaga atttgttatt ttgcaaaata aaaatataaa
     8521 gcaaatgttg gtcaaatcta ataaaaagaa tatttctaaa atcataggaa ataaaaaaac
     8581 aaatgttaaa tatatggaag aaaaatttgg tgtgctttta aaaacacaag aatcagattt
     8641 agatataaat caattagaaa ttgtgttaga tgggaaaagt ttaattagtg ctaatatgag
     8701 agacattcat agaaaattgt atgacattta tgacctttag ttttaataat gaagggagag
     8761 aaaagatttg tatttaaaaa gactagagtt aaagggattt aaatcctttc cagtaaaaac
     8821 agatattatt tttaaagaag gaataacagc catagtagga ccaaatggga gtggaaaaag
     8881 taatatatct gatgctgtaa gatgggtatt aggagaacag agtattaaga gtcttagagg
     8941 tgataaactc gaagatgtaa tatttgcagg tacagataca aaaaaaccta tgaattattg
     9001 tgaagtggct cttactattg ataattctga aaatcaattg gaattagatt ttacagaagt
     9061 aactataaga agaagggctt atagaaatgg tgaaagtgaa ttttttctaa ataataaaag
     9121 ttgtagatta aaagatataa aagaagtctt tttagatact ggtattggaa aagatggtta
     9181 ttcaatcata gaacaaggaa aagtagatga aatattaagt aataatcctt taagcagaag
     9241 aaaagttttt gatgaagctt gtggcatatc aaaatataga tataaaaaac aggaagcaga
     9301 aaggaattta agtaatacaa aggaaaattt agaaagaata gatgatgtat atatagaaat
     9361 tgaaaatcaa ttaaagcctc tttttaatca acagacaaag gcaaaaaagt acttggaaat
     9421 aagtgaaaaa ttaaagacac ttgaagtaaa tagctttata agagaaattg aaggaataga
     9481 aaaagaatta agtgaggtta atgaacatcg taaggttatt gaaaaggagc tcaatgaaaa
     9541 agaagaacaa aaaaatgttg tagagaaaaa gcaagaagat attaataaag aggtagaggt
     9601 attacaagat gtaattgaaa aatctgtaga ttatataaat tcaattaaag gagttatatc
     9661 aaaaaaagag tcccaaataa atttaattaa ggaaagaata agaaatttta cgaatgaaat
     9721 tagtagaaaa aatttagaaa taaaggatat aaaagagaag ctaaatgaaa ataagcaata
     9781 cataaaagaa ttagaaagca ataaattatc aggtagtgaa gaactatcta ccttgcagga
     9841 aaatataaaa gtattggaag gaagtaaaga taaacaaaaa attaagttag aatccctaaa
     9901 taatgagata gaattattga aagaaagtat aattgatata ttaaataaga aacaagagtt
     9961 tagtaataag ctgtctactt taaacgcaaa taaagaaaat atgaatatca gagatgaaaa
    10021 tataaattca gagataacag agttaaacaa aaatattgaa ataaaatcat ctgaattaga
    10081 tactataaat aaagaattta atatgcaaaa tgaaaattta aagaatgtaa ataatagaca
    10141 taaagaatta tcaattaatt tgcaggattc aattagtgaa cacaataaac tagaagatga
    10201 aatacagaaa agtaaatata atttaaatgg atataattca aagttaaatg tctatataga
    10261 tatggaaaat cattatgaag gatttaatag aggagtaaaa gaagtactaa aaaataaaaa
    10321 tttaaaagga gttcatggag cattaggaca gattataaat gtacctgaaa agtatgagaa
    10381 atctatagaa gcagctcttg gtgcttatat gcaaaatata ataactgata atgagtttag
    10441 tgctaagttt gcaataaact atctaaaaca gaataattta ggtagagtaa catttcttcc
    10501 attaaatata attaaatcaa ataaaataag tctaggaaat ttaaaagcaa atactaagtt
    10561 cataggaata gcaagtgatt taattacatt tgatgaaaag tatagaaata taattgaaaa
    10621 tatacttgga agaacaatac ttataaataa tatagatgag ggcataaaat ttgcaaaaga
    10681 aactggtcat aggtttaaaa tagtaacttt agatggtgaa atcttaaatc caggaggttc
    10741 tttgactggg ggaagtctaa aaactaatgg gaatatacta tcgagaaaaa gatacattaa
    10801 tgaatataca gaaaagataa gtaatatcaa gaatgaaatt tcacatctag aattaaaaag
    10861 agaatcttta gacaaagatg tgaaaaatat caaaaatgaa attgattcac atgaaagtaa
    10921 aataaaagat ttagaaaaaa gtataataat aaaaagtaca agtataaaga atgttgagtc
    10981 tgaaattgaa tcgttaaaag gtagtattac taaattagaa aatgagaaga atgatttaaa
    11041 ttctaaccta aattatacac ttgaaaaaag tgatgatgtt agaaaagata tggaagagtt
    11101 agatgattta tacaataaaa ataaagaaaa aattgatgca ttgaatgagg aaataaaaag
    11161 atacaatgat ttatatgata aagaaaaatc tgaatttgat gaattgaact taagtttagt
    11221 gaagaaaaca gaagtttaca atagtatagt tagagatata aaaagaatat ctggtgaaaa
    11281 ttgtgagcta gaagaaaaaa ataaacaatt agaagagtca ttaaattatg aagaacatga
    11341 aataattaaa ttacaagatt ctatactcac tgaagaaaaa gaaaaagaaa atttaacaaa
    11401 acaactaggg gatagtaata gaaatcttga aactagaaaa atagcaaaag atgatttaaa
    11461 aaatagtttt gatgaaatta ataaagaatt aaaaactata gatagacagc atatagaact
    11521 taaagaaagt ttatttaaag ttggtggaag attagaaaga ttaaaaacta gtcaagacac
    11581 atatataaat aagttgtttg agcaatatga tatgacctta gtacaagcat tggaaattaa
    11641 agatgaagat ttggatatag atagaaaatt cttagaaagt ctaaagagag aaataagaag
    11701 tcttggaaat ataaatatag actctataaa ggaatatgag gaaataaaag aaagatacga
    11761 tttttatagc gaacaaaagc aagatttaga agagtctatg gaagagatag aaaaacttat
    11821 acatacttta gaagaaaata tgaaatctga atttgaaatt aagtttgaag aaataagtaa
    11881 aaattttaaa tatgtatata agagattatt tggtggaggt tgtggagaat taactatttt
    11941 agataaagaa aatttattag aaagtgatat actaataaca gctcaacccc caggtaaaaa
    12001 aatgaaaaat ttaaacctat tatctggtgg agagaaagct ttaacggcaa taagtatatt
    12061 atttgctata ttgattacaa agccaacacc attttgtata ttagatgaga ttgaagcgcc
    12121 acttgatgac gcaaatatat ttagatttgg agaatttttg aaggatttat ctaaagagac
    12181 tcaatttata tcagtaactc ataggagagg aacaatggaa gctgctgatt atatctacgg
    12241 agttacaatg caagaaaaag ccatttcaaa agttattagt ttaaaattaa aagaagctca
    12301 ggaaataaca gatattatat aacttagatt gacataggag gaataacagt gttaaaaaaa
    12361 ttatttggtt ttggaaaaga caaggaaaag gaaatagaaa aaaaagatgc tgaagaagaa
    12421 atagaagttg aagacagtgt tgataattta gaaaacttgg aagaaactat tttttcagga
    12481 cttgaagaag aagtgataga taaagtggaa gatattgaag aaaaaaatga ggaaagtgtc
    12541 aataatgaag gcactgaaga aatcgaaaac tttgaaaaaa tagaagttga gatggatagt
    12601 aatggaaaag aagtagaaaa tatttcaaat aatgattctc aagaagagat aatcgaagaa
    12661 ttagaaaatt atgatgaaat tgagtctaaa gagatagaag ataaagaaga taagaaagtt
    12721 aacttgtttg aaagactaaa acaaggattg acaaaagcaa agcaaggaat aactgataga
    12781 atagatgaag ttttaaaatc atatacaaaa atagatgaag aattacttga agatttagag
    12841 gaaattttaa taacagcaga tgttggtgta aatacaacta tggatataat tgaaagacta
    12901 agagataaaa taaagcaaaa aggtattact gaaccaataa aggtaagaga agaacttaaa
    12961 tctatagttg aagatattct tacaaatgaa aactctacac tagatataga accagcacca
    13021 tgtataatat taatggtggg tgtaaatggg gtcggtaaga ctactacaat aggtaaacta
    13081 gcaaatagat acaaaaaaga tggtaaaaaa gttttattag cagcagcaga tacatttaga
    13141 gcagcagcga cagagcaatt agaaatttgg gcaaatagaa ccaatgtaga cataataaaa
    13201 catcaagagg gagcagaccc tggagctgta gtatttgatg ctataaaagc tgcaaaagct
    13261 agaaaaacag atgtattaat atgtgataca gcaggaagat tacacaataa ggctaatctt
    13321 atgaatgaac ttggaaaagt atttaaaata gtagatagag aatttccaga agcaaaacgt
    13381 gaagtacttc ttgtggtgga tgctacaaca ggtcaaaatg cagttgttca agcaaagaca
    13441 tttaaagaag ttgcagatat aacaggtata gtacttacaa aacttgatgg aactgcaaaa
    13501 ggtggagtag tccttgcagt aaaatcagaa gtagatgtac ctgtaaaact tattggagtt
    13561 ggagaaagtg tagaagacct acaagatttc aatgcaaaat cattttcaga tgcattattt
    13621 ggtaactaat gttcttttaa aaataatggt tgacaagagt gttgttatga tataaaatac
    13681 aatagtgtaa agtaaataac ctttacagta tactgctagg aagtgtaaga tatgaatata
    13741 gaaaaaatgg tcgaaattgg attgttattt gaacagtata aagaattatt aactgacaag
    13801 cagaaagaaa tagttgctct atactatgaa gaagattatt ctttaggtga aattagtgaa
    13861 aatctgaatg tatcaagaca aggtgtttat gataccttaa agcgttcaga aaaaatacta
    13921 agagattatg aagaaaagtt acacttagta tcaaagattc aagagcagga aaaaaatatt
    13981 aagattataa aagataaaat tattgacatt aaagaagatt tattgcacaa tagagattgt
    14041 gctaatttaa tccctaagct agaaaatata gaagatgtat gtagggagat gataaaatga
    14101 tatttgaagg attgtctgat aaactacaag gggcatttag taagttaaaa tctaaaggaa
    14161 aacttacaga agtagatgta aaaaatgcta tgagagaagt taaacttgct cttcttgagg
    14221 cagatgttaa ctttaaagta gttaaagatt tcataaaaaa agttcaagag agatgtgttg
    14281 ggcaagaagt tatgcaaagc ttaactccag ctcagcatgt aatcaaaatt gtaaatgaag
    14341 agcttacaag tttaatggga gatgtacaaa gtaaagtaat gatttcctca aagcctccta
    14401 caattttaat gatggttgga ttgcaaggtg caggtaagac tactacagca ggaaaacttg
    14461 gaggatattt taaaaagcaa ggtaaaaaac ctctattagt agcttgtgat atttatagac
    14521 cagcagctat aaagcaactt caagttgttg gagaaaaatt ggatatacct gtattcaata
    14581 tgggagataa agaaaatcca ataaatattg cgaaagcagg tttaagccat gcgattaaaa
    14641 atgctaatga tttagttatt atagatacag ctggtagact tcatatagat gaagtactta
    14701 tggatgagtt aaagtctatt aaatcagaag ttaagccaca tgagatactt ttggttgtag
    14761 attctatgac aggtcaagat gctgtaaatg ttgcagaaag cttcaatgag gcacttggtg
    14821 ttgatggagt agtattaact aaattggatg gagatactag aggtggtgct gcactttcaa
    14881 taagagcagt tacacaaaag cctataaaat ttatggggat gggagaaaag ctagatgata
    14941 tagaaccttt ccacccagat agaatggcat caagaatatt aggtatggga gatgtcttaa
    15001 gtttaataga aaaagcacaa gaaaatatag acttagagaa agctaaagaa ttagagcaaa
    15061 aaattaaaaa acaagagctt gattttgaag atttcttaca acaaatggaa caaatacaaa
    15121 atatgggacc tcttgacaag atacttggta tgatacctgg tatgggaaat gtaaaagacc
    15181 aacttggaga tgtagatttg aatggcaaag aaatgaagag aacaaaagcc ataattcagt
    15241 caatgactac atatgagaga agaaacccag gagtattaaa tgcttcaaga aagaaaagaa
    15301 tagctaaagg cagtggaact agtgtacaag atgtaaatag acttataaaa caacttaatg
    15361 aaatgaaaaa aatgatgaag atgtttgctg gttcacaaaa gagtatgaag aaaaggggcg
    15421 gcttaggcgg tttacctttt tttaaataaa atataaaaaa gtaaaaatta ttcggaggtg
    15481 actgtaatgg cagttaaaat aagattaaaa agaatgggag ctaacaaaaa acctttctac
    15541 agaatagtag tagctgattc aagagctcca agagatggaa aatttataga agaaatagga
    15601 tactataatc caatttctga acctaaacaa gtaagaataa atgatgaaaa agctataaaa
    15661 tggttagcta ctggtgctca gccaacagaa gtagttaaaa aattacttgt aaaaaacgga
    15721 gtaatagaaa aattcgaagc ttctaaacaa gcaaaataat tttttcttgg caattagttt
    15781 aagtaagggc tcattgctaa ggttacttta ggagatgaaa tatatgaaag agctagttgt
    15841 agatatagct aaggctctag ttgataatcc tgactcagtt gttgttgagg aatttgaaga
    15901 taatgatggt atcgtcttaa agcttacagt tgctcaagag gatatgggta aggttattgg
    15961 gaagcaggga agaatagcta aagctataag aactgtcgta agatctgttg caaatagaga
    16021 aaatataaaa gtttctcttg agatagtata aaataggagg attaggtata atgcctagtc
    16081 ctttttatat aaatgcgtag tttaagattt tatgatgata tgaccacata agattaaatt
    16141 ttttaagaag gtgataacat gaaagaaaaa ttaactcatt ttaaggtagg tcaaatagta
    16201 aatacacaag gtttaaaagg tgaagtaaga gtttatccgc ttactgatga tatagagagg
    16261 tttgatgaat taaaagattt ctatctggga aaagatttaa ataataaatt ggctgttgaa
    16321 aaagtaagat acaaaggttc tatggttata atgaagataa aaggcataga cagcatagag
    16381 aaagcagaaa aactaaaaaa taaatttatg tatgtagcta gagaagatag cagagagctt
    16441 gaagaaggcg aattttttat agcagatatg attggaatgg aagttttaac tgtagatgga
    16501 aaatatgtag gaatactaga agatgttctt caatactcag caaatgatgt ctatgtagta
    16561 aaaggtgagg aagataaaga atttatgata ccagctataa aaaaatttgt acctacaata
    16621 gatattgatg aaagaaaaat gattatagac cctattaagg gaatgataga ttaggtggta
    16681 atatgagatt tcatataatg acactttttc cagaaatatt taattcgtac atggatgaaa
    16741 gtataatgaa gagagcagtt gaaaaaggta taattgaggt tcatatatat aatataaggg
    16801 atttttctaa taataaacat aaaaaagtag atgattatcc atttggagga ggagcgggga
    16861 tggtaatgac tcctcaacct atatatgaca catataagca tataataaca actcataata
    16921 taaataaccc aagtgtaatt tatcttactc caaaaggtaa ggtatacaat caatctatgg
    16981 caaagcagat gtctttaaaa gaagatataa tactactatg tggtcattat gaaggaatag
    17041 atgagagaat cattgattta atagttactg atgaaatttc aattggagat tatgtattaa
    17101 ctgggggaga gctcccagca cttataatga tagattctat atcgagatta ataccaggtg
    17161 tattaaacca agaggaatca tttgaagaag aatcatttaa agataactta ttggaatatc
    17221 ctcattacac tagacctaga gattttgaag gattaaaagt accagaagtg cttttatcag
    17281 ggaatcataa gaagatagat gagtggagaa gagaagaatc tataaggata actaaagaaa
    17341 gacgatttga tttatataaa aagtctaatg aaaaataaaa atataatgaa aaattaatat
    17401 atatgtatac aataaagtac ctataaatgg aattaaaaac ataaaagtgc ttgtaataac
    17461 tattgaagta tagtataata taaaatgttg aaaatacggg cgttcctctg tttacactgg
    17521 tcgggtagtt aagaacgtct atgatatcta ggaggaagaa agatgaatga aatgctaaga
    17581 gcaattgagc aagaacaatt aaaaaatgaa gttcctaatt ttggacctgg ggacacagtt
    17641 aaagtacacg ttagaattat agaaggaaaa agagaaagaa tacaagtatt cgaaggtgta
    17701 gtattaaaga gacaaggtgg aggagcaaga gaaactttca cagttagaaa aatgtctttc
    17761 aatgttggtg tagaaagaac tttcccagtt cactctccaa aaatagaaaa aatagaagtt
    17821 actagaaaag gtaaagtaag aagagctaaa ctaaactact taagaggtag agtaggtaaa
    17881 gctgctaaga taaaagaagc tagaaataaa taattaaaaa ctttacttat aaatgggggg
    17941 ctgatttatc agtcctcttt ctattttaat gaaaattaca gcaaataatt atactagaaa
    18001 taaatagaaa tatttgttga aaatatacat tatttatcta tgaatttata gcctttaaaa
    18061 tgaaaaataa aattggtaaa tattgcatta tattttgtaa caatattaaa aataagagaa
    18121 cagtattatg taaagtatga cgttaaaaag atgacaatat tatagtttgt taagatagat
    18181 tttttaagtg gaattaggat ataataatat aatattaata aggagtgata catgtgtcaa
    18241 atgaatacga agagtatctt atgaatgaca atctacatat aaactggtat ccaggtcata
    18301 tgaaaaaaac taaggagtta gtaaaaaata acttaaaatt gattgatgta gtaattgaac
    18361 ttttggatgc tagaatcccg tttagtagta aaaatccaga catagacagg cttgtaggag
    18421 ataagccaag agttgtcgta cttaataaga gtgatatggc agatagggat aaattgaatc
    18481 aatggattga atactataag aaaattaata tcaaagctat accagtagat acaataaaag
    18541 gcgttggtat aaataagata atcgaagaat gtaaaaatgt aactagagaa aaaatgagtt
    18601 ctttaaaaga caaagggaga aaagaaagag ctatacgaat aatgatagtt ggagttccaa
    18661 acgttggtaa atcgtctctt ataaacaaat taacaggtag aaaaagcact caaactggag
    18721 ataagccagg agtaacgaaa gggaaacaat gggttagatt aaagggaaat cttgaacttt
    18781 tagatacacc tggaatactt tggcctaagt ttgaagacca agaagttgca ttaaatttag
    18841 catttagtag agctataaag gatgagattt tagatactga aactttggct ttaagactta
    18901 tagagaaact tatgaaaata gaacctgaga agttgaaagc cagatataag ttagattgtt
    18961 taggagaaac tccaattgaa actatggata tgattggcca taaaagaggg tttataacag
    19021 gtaaaaaaga actagattat acacgcatag ccacaactgt attaaatgaa tttagagatg
    19081 gaaaaatagg aaatataaca ttggaagttc cagaaaacgt taaaagatag attttaaaac
    19141 aaaatcaaaa atttaatgtt aaaaatttaa aaaagccttt tagcaaaggc ttttttattt
    19201 ttttgaaata tagacaaata tctccatata aaagtataaa ttaggttaga aaacctttaa
    19261 aaatattaat ttaagacaaa tatacctaat attttgaaaa ttaaaatgag tgtgattatt
    19321 taaaatttta gcatattgac ttgcttgttt cgtataatat ataataagca caaataaata
    19381 caatatatta aaaatttaat ttatttaatt ttattaattt aataataagt tcttattgtt
    19441 taattcaact tacttatgca agcgtaaaca atcgagacat tttattaatt taataaggtt
    19501 aaaaaggggg attttataat gggtaagacc aaggatgtta tagtatttgg atttgcgtta
    19561 tttgcaatgt tctttggagc aggtaactta atatttccac cttacttggg aataattaca
    19621 ggtccagaat ggttaattgc cttcttagga tttacgtttg ctgatgctgg attggcactt
    19681 ctagcagtaa tggctacagc taaattcgat ggaaacgtag ttgaaatgtt taaaagatgt
    19741 ggtatgaagt tagggattct tataggttgt gcagatattt tatgtatagg cccattctta
    19801 gctataccaa gaacaggtgc aacaacttat gaaatgggta taatgccttt gtttggaact
    19861 tcaattccag tgttattatt ctgtatactt ttttttgcga tttcatatgt actaacaata
    19921 agaccttcta aggtcgtaga tatagttgga cagtttttaa ctccagctct tctaatagct
    19981 ttagcattta taattataaa aggtattata tcacctcttg gagatatagt agataaacct
    20041 atgataccta atgtatttgc agaaggtata ggtcaaggat atcagacaat ggatgctttt
    20101 gcagcaatag cacttgcatc agtgctaata gtatctttaa atgataaagg atattctact
    20161 attagtgaca agttgaaaat gattggtaag gcgggtgttc ttgcttgtgg aggattagct
    20221 ctagtttatg gaggattatg tttccttggg gcaactgtat caacaatgta tggaacagat
    20281 gcagtacaat cacaagtaat agtaaatata actgaaggat tgcttggaaa tgttgggaaa
    20341 gcgattttag cagtagtagt atcattagca tgtttaacta catctatagg tcttacatct
    20401 gctacaggtc aatatttctc tagacttaca aaaggtaaat tgagttatga aaaaatagta
    20461 ttagctgtat ctgtattcag tgcagtagta gcatcttttg gtgttggaac tataataaag
    20521 atagcatctc ctatactaag tatagtttat ccaccatcaa ttgttttaat aattttagct
    20581 ttcttcaatg aaaaaattaa gaatgataat gtatacaaag gagcagtata tatgtcattg
    20641 cttgtaagta tactaacagt tatatctagt tatggagtag ctgttccagt agtaaattct
    20701 ttacctctta attcattagg atttaactgg gtggtgccag ttataatagc tggaataatt
    20761 ggtaatttta taccatcaaa gagtcaatct aatacacttg gaacaaacta agttttgttt
    20821 aattaaaata taatcaattg taaataaatg agttaactaa aagtaaaagg agttatttgt
    20881 acaaataact ccttttattt
//
LOCUS       DAMKNB010000064        20771 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.066, whole genome shotgun sequence.
ACCESSION   DAMKNB010000064 DAMKNB010000000
VERSION     DAMKNB010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 20771)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20771)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20771
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.066"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            complement(25..867)
                     /locus_tag="PC494_002617"
     CDS             complement(25..867)
                     /locus_tag="PC494_002617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HDF3913108.1"
                     /translation="MIIQQIYNNNVVLVLDENIKKELILTGCGIGFQKKKGQEIDKSK
                     IERTFVIQDESFLDKISKLASQVDEKFFEVSTEIIAYAEENLNTKLYEYIYVALTDHI
                     AFAIKRYHENITIKNDLLHEIKRIHKKEYEIGKWAVDYINKEFDVKFPVDEAGFIAMH
                     IVNSNYKGSSKESLLITKIVKDILNIIRYYYRVEFKEDDINYDRLLTHLKFFAKRLVK
                     KEKINDTNNEIIDIIKVKYEKDYDCAYKIKTHVEKNYDYYVSQDELLYLTLHIKRVIS
                     VLNL"
     gene            complement(1128..3170)
                     /locus_tag="PC494_002618"
     CDS             complement(1128..3170)
                     /locus_tag="PC494_002618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:proton antiporter"
                     /protein_id="HDF3913109.1"
                     /translation="MSILVTLLGLLVCTTISTVFSKKWSNIPLAIYQIVLGIILSILP
                     FKFSFSFNPEIFVICIIAPLLFSEGQNVSRKELLELRKPILLLAFGLVLITVFAGGIF
                     IHFLIPGMPLSVSFALAAVISPTDLVAVKSITQGLNFPKNMMSILEGESLLNDAAGVV
                     AFKVAVLATVTGVFSIEEAGIQFMITAFGGIIVGSILGYIIIKIRLSLHKWNLEEIPM
                     VIVIQIMTPLFVYFVAEEIGVSGILAVVMAGIAHGIEKEHLQNTTTKLRIISDNTWYV
                     LEYVLNGFVFTLLGFLLPSIYTGLSSKNENMALELTFISTLIVLILFVIRFIWVYLWH
                     NSFIKPKKNPLNNFFVGFLGFKDEEVVKESISKCKYSLIVATCGVHGTFTLATALSIP
                     FYLADKDVFPMRDTVLFISSEVILISLVLATVLLPRLLKNNVQESEPLLSDKEAYKLI
                     LKEAILKLSNEKAQEVQPVIHDLNEQLVDSEKGILNTPDNKLISMMIAEADQQGLLAV
                     LKLLEDGKISDRAFKLYRFYITKSRKSVQKSIFKIVKLKISMWIINRKVKKEVKEKIT
                     KIVSENKEIIKEFHHAYALSTKTAISFINKNTDEDNRHEALIAIRFYNRYLNWITRKI
                     QNDDKFEARVEYYRVMAIQSQRDSVQQLVETKQISREVAKELLENILYDEMMMIES"
     gene            complement(3322..4293)
                     /locus_tag="PC494_002619"
     CDS             complement(3322..4293)
                     /locus_tag="PC494_002619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptide ABC transporter ATP-binding protein"
                     /protein_id="HDF3913110.1"
                     /translation="MKKEESLLKVEGLKKYFEVKSGLFDKEIKCVKAVDGISFDLKKG
                     ETLAIVGESGCGKSTAGRTILRLIEKTEGKVEFNGVDIYKLEKEELRKLRPKMQMIFQ
                     DPYSSLNPRLNVEQIISEAVIEHNLVPKNEIKDNILNVVESCGLSKYHLNRKPGEFSG
                     GQRQRIGIARALALNPEFIVCDEPVSALDVSIQSQIINLLMDLQDKYKLSYLFISHDL
                     SVVNHIAHRVCVMYLGSIIEIATKGELYLHSQHPYTKALMSAVPIQDPTIKKNRIILK
                     GDIPSPTNPPSGCKFHTRCPYCKEICKKEIPVLKEISRNHFVACHLV"
     gene            complement(4294..5271)
                     /locus_tag="PC494_002620"
     CDS             complement(4294..5271)
                     /locus_tag="PC494_002620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF3913111.1"
                     /translation="MSKALIEVKDLKVYFHTDKGIVKSVNEVSFNINEGETIGIVGES
                     GCGKSVTAMSLMKLLPTSKIEGGEIIFRGKDILKMNEDELMGIRGNEISMIFQEPMTS
                     LNPAFTVGSQIIEGIMIHQDLSKEEAKKKVIDMIKLVEIPRAEEIYNSYPHELSGGMR
                     QRIMIAMALSCNPKLLIADEPTTALDVTIQAQILDIMKNIKEKLNTSIMMITHDLGVV
                     AEMCDKVLVMYAGKIIEVAEVVELFKNPKHPYTIGLLKSKPALGKNKDKRLYSIPGQV
                     PNPIGMPDSCYFSDRCEKVCDKCRTQIPPLIELNSGHSIACWLYKKEEI"
     gene            5490..7049
                     /locus_tag="PC494_002621"
     CDS             5490..7049
                     /locus_tag="PC494_002621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDF3913112.1"
                     /translation="MKFKKLASLILVSSLMLTFTACASNDKDKSSGSKSGGTVVIPMA
                     SDPDIINGAFANVKEDSLASNIVYAPLYTYEKGNLVNYLAEKVDFKDSKELTIKLKSN
                     LKWHDGKPITAEDVLFTFNTVLDEKQNSPSRQYLLVGEKPVKVEKIDDLTVKITLPTA
                     SESFLYGISKISPIPKHVFEGESNIAKSEKNNNPVGSGAFKFKEWKKGESIVFEKNAD
                     YFGGEPKADSIALKIIPNEASQEAALNNGEISLMKTSAEGYEKAKSNSNLQTYTYSEE
                     RLNYIVFNQNISNMANKEVRQALSYALNRNEMIESAYGKEGSVPAKSILVPEADFYTE
                     EGVEGYDQDTNKAKDLLDKSGVKIDKLKIGYNTGRFGHKNYALVAQQELKKIGIEAEI
                     VPYESKAFFNILFSNSTECDMYVNGYAWGLEPNPYRGMFETGQYCNQTKYSNAEIDAL
                     WEKGFTELNKEKREEIYKQIQQDISKDAPIYTIDYEQNLMAAQKNLKGIKDAKPSPAI
                     LFEDWSKLYVE"
     gene            7155..8114
                     /locus_tag="PC494_002622"
     CDS             7155..8114
                     /locus_tag="PC494_002622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF3913113.1"
                     /translation="MLKLILNRVKVLIPMLILISILSFGLLELAPGDPADAYINPLMS
                     SQDIENIRVNMGLDKPVYIRYLNWLKNTLSGNLGISYINHMPVTEQIMEKMGNTFILM
                     GTSLIFSILVAIPLGIFLAVNKNSITSKVSSVFNYIGVSIPSFWIGMILISIFSVKLN
                     IFPSGGMHTIGNDSIGDLVKHLVLPVITLGLYNTAIFTNYVEASVNEQLKKQYVITAR
                     AKGLSEKVILFKHVLKNSLTSLVTILGMSIQKLVTGAFVTEVVFSWPGMGRLMIDSIF
                     SRDYTVIMAITMLSALFLILGNLVADILYLLIDPKIKSSKGGF"
     gene            8117..8929
                     /locus_tag="PC494_002623"
     CDS             8117..8929
                     /locus_tag="PC494_002623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF3913114.1"
                     /translation="MFTSILKKLKKDKSFAFACITLSIIIILIITSFILNIDSNAIDT
                     TSKLQEPSLKHIFGTDELGRDYFSRALYGGRISLSVGILSMLISVVFGTAVGVISGYI
                     GGKLDQFLMRLVDMLMSIPSFLVLIVLNTYLTPKVSTIILIIGFLSWMEVSRIVRGET
                     LKIKENEYCLAAKATGIKTRNILLRHIVLNLKETIVVAGSLNIANAILTESALSFLGL
                     GIQLPLASWGNMLQDAQRHIFDKLYLAVFPGLLIFLTVMSLTIISKKFSSNT"
     gene            complement(9145..10047)
                     /locus_tag="PC494_002624"
     CDS             complement(9145..10047)
                     /locus_tag="PC494_002624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDF3913115.1"
                     /translation="MDIKQLKYFVEIVKSGFNLSIASKTLHISQPALSQIIKNFEESE
                     DVYLFERYKGRLNGLTPAGERFYVNAEHIINEYKNMMEDLREDSVQFKGKVRIGIPPL
                     ILGIAFSDVVAQLVANNPDIEFDIVEKGAYDLNRMLILQELDYAVLLHPHKIDKSVVT
                     EHVLQEDELTAFLNINHPLAKKDKIDWNDLNEQLLAIFNPTFMIHHKLMQKFTDENVK
                     LKRYIMSGSWDFLLLSTTNSDFITILPSPVHDFFENSKIIEKPFNHPITWKVILCRPK
                     KERYSHVDQHVFKFIIDFFSKKNS"
     gene            10402..11580
                     /locus_tag="PC494_002625"
     CDS             10402..11580
                     /locus_tag="PC494_002625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000786547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA C-acetyltransferase"
                     /protein_id="HDF3913116.1"
                     /translation="MKDVVIVSAVRTPIGSFGGVFKNTSAVQLGTIAVKEAISRVRLN
                     LSEIDEVIIGNVLQTGLGQNVARQIAINAGIPNSVPSYTVNKLCGSGLKSVQLAAQSI
                     TSGENDVVIAGGTENMSQAPYIVPTARFGSKMGDITMVDSMLTDGLIDAFNQYHMGIT
                     AENIATKFEFTREMQDKLALESQNKAENAIKNNRFKEEIVPVDILIRRGKIETIDKDE
                     YPKLGMTFEGLAKLKPAFKKDGTVTAGNASGINDGAAMLILMSQQKADELGIRPLAKI
                     KSYASAGVEPEVMGTGPIPATRKALKKAGLSINDIDLIEANEAFAAQALAVKNELQID
                     SSKLNVNGGAIALGHPIGASGARILVTLIYEMQKRKVETGLATLCIGGGQGISMVVSR
                     "
     gene            11589..12245
                     /locus_tag="PC494_002626"
     CDS             11589..12245
                     /locus_tag="PC494_002626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA transferase subunit A"
                     /protein_id="HDF3913117.1"
                     /translation="MNKIVSIDEALSHVKDGDTIMVGGFMANGSPENLIDYLCSKNIK
                     DLTLICNDTGFIDKGVGKMVVNKQFKKIIASHVGLNKETGRQMNNNETDVELVPQGTL
                     AEQIRAAGYGLGGILTPTGIGTLVEEGKQKIVVDSKEYLLEKPIYADVALLFASKVDK
                     AGNLVYKGSMNNFNNLMASAAKITIVEADEIVEIGDIDPNEVNTPGIFVNYIVEGGNL
                     "
     gene            12245..12910
                     /locus_tag="PC494_002627"
     CDS             12245..12910
                     /locus_tag="PC494_002627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacid CoA-transferase subunit B"
                     /protein_id="HDF3913118.1"
                     /translation="MDKLEMQEYIANRVSKELKDGAVVNLGIGLPTKVANYIPDNVNV
                     ILQSENGFLGLGSAEDGNSSDETIVNAGGQPVTILPGGCFFDSATSFGIIRGGHVDIT
                     VLGALQVDKYGNIANYMIPGKMVPGMGGAMDLVTGAKKVIVAMEHTSKGSAKILNNCT
                     LPLTATNAVDLIVTEMGVMEVTSDGILLKKINPAFTLDDVISATEAPLILSDSLNGKI
                     SVV"
     gene            13015..13791
                     /locus_tag="PC494_002628"
     CDS             13015..13791
                     /locus_tag="PC494_002628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxybutyrate dehydrogenase"
                     /protein_id="HDF3913119.1"
                     /translation="MVKDKVVFVTGAASGIGKQIAESFLKNGAKVMFSDINQESLNNT
                     ITELQKKGYDCMSVKCDVTKEEEINHAIDKTVEKYGRLDILINNAGLQHVSMIEDFPT
                     DKFEFMIKIMLTAPFIATKKAFPIMKKQGFGRIINMASINGVIGFAGKAAYNSAKHGL
                     IGLTKVAALEAADSGITVNALCPGYVDTPLVRGQFNDLSKTRNIPLENVLEEVLYPLV
                     PQKRLLDVQEIADYAMFLASDNAKGITGQACLLDGGYTAQ"
     gene            13853..15187
                     /locus_tag="PC494_002629"
     CDS             13853..15187
                     /locus_tag="PC494_002629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntP family permease"
                     /protein_id="HDF3913120.1"
                     /translation="MSIIAPIGIIIGIIAIIYFSVKEIHITIAAPIATLIVVILNKMD
                     VVTSMLGADKNNYMGALGNYIMSYFAIFLLGSILAKFMEESGATVSIADFILNKFGSN
                     HPYRVLVAIFIVSFILTYGGISLFVVMFAVIPLARTLFKKLDISWNLIQIPLWLGIAT
                     ITMTIIPGTPAIQNVIPIQYLNTSLTAATIPSIVGSIGCATFGLVYMKYALNKSIRKG
                     ETYATYTSELEEESLDRELPGFFASIFPLLALVIIAITGSTFGSEFMKKNVIYIALIV
                     AILLSAFLFHKFLSSKIQTLSIGASGSIGPIFATSSAVAFGAVIMAAPGFDVFSKLIM
                     SIPGSPLISLTVLTSTMSAITGSSSGALGIVMPNFADYYLSTGLNPELIHRVATIASN
                     ILTIVPQSGVFLTFLSLSKLTHKTGFKETFIVVAVGSLIAEIIVITLGLLMY"
     gene            15684..16610
                     /locus_tag="PC494_002630"
     CDS             15684..16610
                     /locus_tag="PC494_002630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation protein"
                     /protein_id="HDF3913121.1"
                     /translation="MMRRNIPTKLKTILALGVLTLATASSAVTASASSLENNVNISNK
                     SLVYSNTKYKFSAKPNCSVKPELKPDKDNSCKDKNHNDKNCNNTNKPEDNNNSDSTNK
                     PDNNKPESNKPEDNNNSGSTNKPDNNKPESNKPEDNNNSGSTDKPDNNKPESNKPEDN
                     NNSDSTNKPDDNNNSGSTSESFSAYQKEVVDLVNIERAKAGLNPLTLDSSISNVATKK
                     SQDMIDNNYFSHNSPTYGSPFDMLKKFGISYKTAGENIAMGQKTPKEVVNAWMNSEGH
                     RKNIMNPNFSKIGVGVAQKSGGSIYWTQIFVG"
     gene            complement(17003..20542)
                     /gene="nifJ"
                     /locus_tag="PC494_002631"
     CDS             complement(17003..20542)
                     /gene="nifJ"
                     /locus_tag="PC494_002631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009900447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate:ferredoxin (flavodoxin) oxidoreductase"
                     /protein_id="HDF3913122.1"
                     /translation="MAKFMKTLDGNTAAAHVAYAFTDVAAIYPITPSSTMAEVVDEWA
                     SQGRKNIFGQTVNVVEMQSEAGASGTFHGSLQGGALTSTFTASQGLLLMIPNMYKVAG
                     ELLPGVFHVSARALASQALSIFGDHQDVMAARQTGCVLLASGSVQEVADIAPVAHLAA
                     IEGRLPFIHFFDGFRTSHEIQKVELLENEDYASLLNFEAVQAFRDNALSPNHPVARGT
                     AQNPDIYFQTREASNKYYQNIVGIVEKYMEKMSNLTGRKHSLFDYYGAEDAKYVLIAM
                     GSVTETIEETIDYLNAKGEKYGLVKVHLYRPFSMKHFLDAMPSTVERICVLDRTKEPG
                     STGEPLYLDVRDVFYGKENAPMIIGGRYGLGSKDTTPSDIKTVFDNLVSEQPKNGFTV
                     GIVDDVTNTSLTPSEPIKIASKGTIRCKFWGLGSDGTVGANKQAIKIIGDHTEKYAQA
                     YFDYDSKKSGGITMSHLRFGDTPIRATYLIDEADYIACHKQSYVYQYDLLKGLKKGGT
                     FVLNTIWDQAGLEEHLPAHMKQYIAKNDIKFYTVNAVKLGQEIGLGNRINMIMQSAFF
                     KLAEIIPEEDAVKYLKDSIVKAYGKKGEKIVNMNYAAVDAGINALVKVEVPASWENAV
                     DADKGEVKEPEFIKNILRPMTAQEGNNLPVSTFNGIEDGTFPCGTAAYEKRGIAVDVP
                     EWIIDNCIQCNQCSFICPHACIRPVLVTEEELANAPEGFEAKKALGKGLEGLKYRIQV
                     SPLDCTGCGNCADICPAKEKALVMKPIDTQLDTELDNWAFAVNPDEVAPKVDVMPANT
                     VKGSQFRQPLMEFSGACAGCGETAYIKVVTQLYGDRMMIANATGCSSIWGASAPSIPY
                     TCNHEGKGPSWANSLFEDNAEYGFGMYTAVKQIRNKIVDAMTELVSMDICEDAKAVFT
                     EWLDSRNDGEASKVASAKVVELLEKPACDCTDEKAKELVKAIKDRKDYLVKRSQWILG
                     GDGWAYDIGYGGLDHVLASGEDVNVLVFDTEVYSNTGGQASKATPAAAMAKFAASGKK
                     SRKKDLGMMAMTYGNVYVAQVAMGADKNQFIKAVLEAEKHDGPSLIIAYAPCINHGLK
                     EGMGRTVANEAQAVACGYWHLYRFNPEVKAEGKNPFTLDSKEPTASFKDFILAQVRYS
                     AIAKQFPEEADGLFAKAEADAKERYEGYKKLAE"
BASE COUNT         7183 a         3264 c         2913 g         7411 t
ORIGIN      
        1 cattctgtat taaactactc tttattataa attcagtaca gatataactc ttttgatatg
       61 taatgttaaa taaagtagtt catcttgact tacatagtaa tcataattct tttctacatg
      121 agtttttatt ttatatgcac aatcataatc cttttcatac tttactttaa ttatatctat
      181 aatttcatta tttgtatcat tgattttttc tttttttact aatcgttttg caaagaattt
      241 taaatgagtc agaagcctat cataatttat atcatcttct ttaaattcaa ctctataata
      301 atatcttata atatttagta tgtcttttac aattttagta attaatagtg attcctttga
      361 acttccctta tagtttgaat ttactatatg cattgctata aaaccagctt catctactgg
      421 aaatttcaca tcaaattctt tatttatata atctacagcc catttcccaa tctcatattc
      481 ttttttatgt attcttttta tctcatgtag taaatcattc tttatagtta tgttttcatg
      541 atatctttta attgcaaatg caatatggtc agtaagtgct acataaatat attcataaag
      601 cttagtattc aaattctcct ctgcataagc aattatttca gtactaacct caaaaaattt
      661 ctcatcaacc tggcttgcta gtttactaat tttatctaaa aagctttcat cttgtattac
      721 aaaagttctt tcaattttac ttttatctat ttcttgacct ttcttttttt gaaacccaat
      781 tccacatcct gttaatatta attctttttt tatattttca tctaaaacta atacaacatt
      841 attattataa atttgttgaa taatcataat caatatctct cccaaaatac aatttccctt
      901 attcataaaa aaatacctaa attaagatac aattcacctg tataccttaa cctaggtatt
      961 gcctgcttac cagtaacaat ccagcttgtt aacgcttata tattgtattc aatttatggt
     1021 tttattctat tataaataaa tatatatgtc aagtaaatta ttgaaaacta tttcctattt
     1081 tttagtatta attttaacat caaaaatcaa attttattcc attatattta tgattctatc
     1141 atcatcattt catcatagag aatattttcc aataactctt tagccacttc tcttgatatt
     1201 tgcttagttt caactaattg ttgaacactg tctctttgac tttgtatcgc cattactctg
     1261 tagtattcta ctcttgcctc aaacttatca tcattttgaa tctttctagt aatccaattc
     1321 aaataacgat tatagaatct gattgctatt aaggcctcat gtctgttatc ttcatcagta
     1381 tttttattta taaatgatat agcagtttta gtagaaagtg catatgcatg gtgaaactct
     1441 ttgattattt ctttattctc agatactatt tttgtaattt tttcttttac ttctttcttt
     1501 acttttctat ttataatcca catgcttatt tttaatttta caattttaaa tatagatttt
     1561 tgaacagatt ttcttgattt tgtaatataa aatctataca atttaaaggc tctatcagaa
     1621 attttaccat cttctaatag tttcaaaaca gctaataatc cctgttggtc tgcttctgca
     1681 atcatcatac ttataagttt attatctgga gtatttagta ttcctttttc tgagtctacc
     1741 aactgttcat ttaaatcatg tataactggt tgtacttctt gtgctttttc attactaagt
     1801 tttaaaatgg cttctttcaa aattagttta tatgcctctt tatcagataa taaaggttct
     1861 gactcttgta cgttattttt taataatctt ggcagtaaaa ctgttgccaa tactaaactt
     1921 ataagaataa cttctgatga tataaataaa acagtatctc tcattggaaa tacatcttta
     1981 tcagccaaat aaaaaggtat agataaggca gttgctagtg taaatgtacc atgaacacca
     2041 caagtagcaa ctattagtga gtatttacat ttagaaatac tctcttttac aacttcttca
     2101 tccttaaaac ctaaaaaacc tacaaaaaaa ttatttaaag gattcttttt aggttttata
     2161 aaagaattat gccataaata tacccatata aatcttataa caaataaaat aagtacaatt
     2221 aaagtagaaa taaaagtcaa ttccaatgcc atattttcat ttttactact aagtcctgta
     2281 tatatacttg gtaacaaaaa accaagcagt gtaaagacaa atccattcaa tacatactcc
     2341 aaaacatacc aagtattgtc tgatattatc cttaatttag tagttgtatt ttgtaaatgc
     2401 tctttttcaa ttccatgagc tatccctgcc attacaacag ctaggattcc agatactcct
     2461 atttcttctg ctacaaaata tacaaaaagt ggagtcatta tttgtataac tattaccatt
     2521 ggaatttctt ccaaattcca cttgtgtaaa ctaagtctta tttttataat tatgtatcct
     2581 aaaatacttc ctactattat tcctccaaaa gctgtaatca taaattgaat ccctgcctct
     2641 tctattgaaa aaactcctgt aactgtggca agtactgcaa ccttaaatgc tactactcca
     2701 gcagcatcat ttaataaaga ttcaccttca agtatactca tcatattttt aggaaaattt
     2761 aatccttgtg taattgattt tactgctact aaatcagttg gagatattac tgctgccaaa
     2821 gcaaatgaaa cagataatgg catcccagga ataagaaaat gtataaagat tccacctgca
     2881 aacacggtta ttaaaactaa accaaatgca agaagcaaaa ttggttttct gagctctaat
     2941 agctcttttc tcgatacatt ttgtccttca ctgaatagta atggagctat gatacatatt
     3001 acaaatattt ctggattaaa tgaaaatgag aatttaaatg gcaaaataga caatataatc
     3061 cctagtacaa tttgatatat tgcaagagga atattactcc actttttgct aaatacagtt
     3121 gaaatcgttg tacaaaccaa taatcccaac aatgttacta aaattgacat aactacctct
     3181 cttttcaata ataatattat agattaaact tatatatcaa ctaacttaat attaacagca
     3241 tgaaatccca tcttaatcaa aaaaattttc agtttattct attattctta ttatatacat
     3301 caaatttaat ttttgaaata tctatactag atgacatgca acaaaatgat ttcttgatat
     3361 ttcttttaaa actggaatct cttttttgca tatttcctta caataagggc atcttgtatg
     3421 aaacttacat ccacttggtg gatttgttgg agatggtatg tctcctttta atataattct
     3481 atttttctta attgtagggt cttgtattgg tactgcgctc ataagcgctt ttgtatatgg
     3541 atgttgagaa tgtaagtaaa gttctccttt agttgcaatt tctattatag aacctagata
     3601 cataacacaa actctatgtg caatatgatt tactacactc aaatcatgag atataaataa
     3661 atatgaaagt ttatatttat cctgtaaatc cataagtaaa tttataattt gagattgaat
     3721 agaaacatct agtgcagaaa caggttcatc acaaactata aattctggat ttaatgctaa
     3781 tgctcttgct atacctattc tctgtctttg acctccagaa aactcacctg gttttctatt
     3841 taaatggtac ttagaaagac cacaactttc tacaacattt aatatattat cttttatttc
     3901 attctttggc actaaattat gttctataac tgcctcggat attatttgtt ccacatttaa
     3961 tcttggattt aatgaactat atgggtcttg aaatatcatt tgcattttgg gtcttaactt
     4021 tctaagttct tccttctcta acttatatat atctacacca ttaaattcaa ctttaccttc
     4081 agttttttca attaatctaa gaatggttct tcctgcagtt gattttccac atcccgattc
     4141 tccaactata gccaaagttt ctcctttttt taaatcaaaa gaaattccat ctactgcctt
     4201 tacacattta atttccttat caaataatcc agatttaact tcaaagtact ttttaagacc
     4261 ttctactttt aataaactct cttctttttt caattatatc tcctcctttt tatataacca
     4321 acatgcaata ctatgaccac tattcaattc tattaaagga ggtatctgag ttctacattt
     4381 atcacatact ttttcacatc tatcactaaa ataacatgaa tctggcatcc caattggatt
     4441 tggtacttgt cctggaatcg aatacaatct tttatctttg ttttttccaa gagcaggctt
     4501 tgattttaga agtccaatag tataaggatg ttttggattt ttaaataatt caacaacctc
     4561 tgccacttct ataattttac cagcatacat cactaatact ttgtcacaca tttctgcaac
     4621 tactcccaaa tcatgtgtaa tcatcattat agatgtgttt aatttttctt ttatattttt
     4681 cattatatct aaaatctgag cttgaatagt aacatctaaa gctgttgttg gttcatcagc
     4741 tataagtaat tttggattac atgataaagc catagctatc attattcgtt gtctcatacc
     4801 acctgataat tcatgtggat atgaattata tatttcttca gctcttggta tttctaccag
     4861 ttttatcata tcgattacct ttttcttagc ttcttccttt gataaatctt gatgtatcat
     4921 aataccttca atgatttgac ttccaacagt aaacgctggg tttaaagatg tcattggttc
     4981 ttgaaaaatc attgatatct cattccctct tattcccata agttcatctt cattcatctt
     5041 taaaatgtct ttgcctcgaa agattatttc tccaccttct atttttgatg ttggaagtaa
     5101 cttcatcaaa gacatggctg ttacagactt accacatcct gattctccaa ctattccaat
     5161 agtttcacct tcatttatat taaaacttac ttcatttaca ctctttacaa tccctttatc
     5221 tgtatgaaaa taaactttta aatctttaac ctcaattagt gctttactca ttattttctc
     5281 ctctcagcaa aattacttaa gataacatac accttttgat tgtattttat aaaaatttaa
     5341 attacaacat tttcttacat tttattattt ttttctatta attataataa tataatagtt
     5401 aatttctata tatattgatt taataatgat tactattata caataaaaaa tatgtgttaa
     5461 atattatttt atggaggttt tataagaata tgaaatttaa aaaattggca tcattaatct
     5521 tagtttcatc attaatgctt acatttacag cctgtgcttc caatgataaa gacaagtcta
     5581 gtggaagcaa atctggtgga actgttgtaa tacctatggc aagtgaccca gatataatca
     5641 atggagcttt tgcaaacgtt aaagaagact ctcttgcatc aaatatagtt tatgctcctc
     5701 tttatactta tgaaaaagga aatttagtaa attatttagc agaaaaagta gattttaaag
     5761 atagtaagga attaactata aaattaaaat ccaatttaaa atggcatgat ggaaagccaa
     5821 taactgctga agatgtctta tttacattta atacagtttt agacgaaaaa caaaattcac
     5881 catcaagaca atacttattg gtgggtgaga aaccagttaa agtagaaaaa attgatgatt
     5941 taacagttaa gattacttta ccaactgcaa gtgaatcttt cttatatggt atatctaaaa
     6001 tttctccaat accaaaacat gtgtttgaag gagaatcaaa tatagctaag tcagaaaaaa
     6061 ataataatcc agttggttct ggtgcattca agtttaagga atggaaaaaa ggtgaaagca
     6121 tagtatttga aaagaatgca gattattttg gtggagaacc taaggcagat tctatagcgc
     6181 taaaaataat tcctaatgaa gcatctcaag aagcagcttt aaataatggc gaaatttcac
     6241 ttatgaagac atctgctgaa ggatatgaaa aggcaaaatc aaactcaaac ttacaaactt
     6301 atacttatag tgaagaaaga ttaaactaca ttgtatttaa ccaaaatata tcaaacatgg
     6361 ctaacaaaga agtaagacaa gccttatcat atgccttaaa tagaaatgaa atgatagaat
     6421 cagcatatgg aaaagaaggt tctgtacctg ctaaatctat attagttcca gaagcagact
     6481 tctatacaga agaaggtgtt gaaggatatg accaagatac aaataaggct aaagatttat
     6541 tggataaaag tggtgttaaa attgataaat taaaaatagg ttataacaca ggtagatttg
     6601 ggcataaaaa ctatgcctta gtagctcaac aagagttgaa aaaaattggt atagaagctg
     6661 aaatagttcc ttatgaaagt aaggcattct tcaatatact atttagtaat agcactgaat
     6721 gtgatatgta tgtaaatggt tatgcttggg gattagaacc aaacccatat agaggtatgt
     6781 ttgaaactgg tcaatattgc aaccaaacta aatattctaa tgctgaaata gatgctttat
     6841 gggaaaaagg atttactgag ttaaacaagg aaaaacgtga agaaatatat aagcaaatac
     6901 aacaggatat atctaaggat gcgcctattt acactataga ttatgaacaa aatttaatgg
     6961 cagctcaaaa aaatctaaaa ggaataaaag atgctaaacc atctcctgca atattatttg
     7021 aagattggtc taaactgtat gtagaataat tgatgtaaaa ttttatatta ttaattagaa
     7081 aaggagatgt ctaaaaataa tattgtttta ttattttaaa acgagacatc tcttttaatt
     7141 aggagaattt acttatgtta aaattaatat tgaatagagt aaaagtttta atacctatgt
     7201 taatcttaat atctatatta tcatttggac ttttagaatt agctcctggt gacccagcag
     7261 atgcatatat aaatccttta atgtcttcac aggatattga aaatataagg gttaatatgg
     7321 ggcttgataa accagtatat ataagatatt taaactggtt gaaaaacact ttaagtggaa
     7381 acttaggtat ttcttatata aaccatatgc ccgttacaga acaaattatg gaaaaaatgg
     7441 gaaatacatt tattcttatg ggtacttctt tgatattttc aatattggta gctatacctc
     7501 ttggaatatt tttagctgta aataaaaatt caataactag taaagtatca tctgttttta
     7561 attatatagg tgtttctata ccttcttttt ggataggtat gatactcatt tcaatttttt
     7621 cagttaaact taacattttc ccatcaggag gtatgcatac tattggaaat gatagtattg
     7681 gagatttagt aaaacattta gttttgcctg taataacttt aggtctatat aatactgcta
     7741 tttttacaaa ttatgtagaa gctagtgtaa atgaacaatt aaaaaaacaa tatgttatta
     7801 cagcaagagc aaaaggatta tcagaaaaag tcatactatt taaacatgtc ttgaaaaatt
     7861 cactgacatc attggttaca atcctaggca tgagtataca aaaattagtc actggtgcat
     7921 ttgttacaga agtagttttc tcttggccag gtatgggaag attaatgatt gattcaattt
     7981 tttcaagaga ttatactgta attatggcaa taactatgtt atcagcacta tttttaattt
     8041 taggtaattt agttgctgat atactatact tattaattga ccctaaaata aaatctagca
     8101 aaggaggatt ctagttgtgt ttacaagtat cttaaaaaaa ttaaaaaaag ataaatcctt
     8161 tgcttttgca tgtattactc ttagcataat aatcatatta attataactt cttttatatt
     8221 aaatatagac tctaatgcaa ttgatactac ttctaaactt caagaaccta gcttaaagca
     8281 tatctttggt acagacgaac ttggtagaga ttacttctct agagctcttt atggtggaag
     8341 gatttcactt agtgttggta ttttatcaat gcttatttct gtagtatttg gtactgctgt
     8401 aggtgttatt agtggatata ttggaggtaa gctagaccaa ttcttgatga gattagtgga
     8461 tatgcttatg agtataccaa gtttcttagt tttgattgta ttaaatactt atctaacacc
     8521 taaagtttcc actattatac taattattgg attcttaagt tggatggaag tttcaagaat
     8581 tgtacgtggc gaaacattaa aaataaagga aaatgaatac tgtctagctg ctaaagctac
     8641 tggtatcaaa actagaaata tactattaag acatatagtt ttaaacttaa aagagactat
     8701 tgtagttgct ggttcgttaa atattgctaa tgctatctta actgaatctg ctcttagttt
     8761 tttaggtctt ggaatccaat tgcctcttgc atcatggggt aatatgcttc aagatgctca
     8821 aagacatatt tttgacaagt tatatttagc tgtatttcca ggattactta tatttttaac
     8881 agtcatgagt ttgactataa taagcaaaaa attttctagt aatacttaac aaattttata
     8941 tagaaaataa aaacagtgat tatctaaaga tatacactgt ttttattttt cgtttaaaaa
     9001 aatacatatt ttgtatatta taactttaaa tactactcta ccatgttatg taaagcctat
     9061 tattgctctc aaacatatag atgaaaaact aatagtttat tataataaaa attgatttat
     9121 ttatttgtta ttttaataac atttttaaga gttcttttta ctaaagaaat ctataataaa
     9181 tttaaataca tgttggtcta catggctata acgttctttt ttaggtctac atagtataac
     9241 tttccatgta ataggatgat taaaaggctt ttctataatt ttgctatttt caaaaaaatc
     9301 atgaactggt gatggtagaa ttgttataaa atcagaattt gtggttgata gcaacaaaaa
     9361 atcccatgaa ccagacatta tatatctttt taacttaacg ttttcatcag taaatttttg
     9421 cattagctta tgatgtatca taaaagtagg attaaatatt gcaagtaact gctcattcaa
     9481 atcgttccaa tctatcttat ccttcttagc aagtggatga tttatattta aaaatgctgt
     9541 aagttcatct tcttgaagca catgttcagt tactacactt ttatcaattt tatgtggatg
     9601 taacaatact gcataatcta attcctgtaa gataagcatt ctatttaagt catatgcacc
     9661 cttctctact atatcaaatt ctatatctgg attatttgca actaactgtg caactacatc
     9721 tgaaaatgct attccaagta taagtggagg tattcctatt ctaacttttc ctttaaattg
     9781 aactgaatct tctcttaaat cttccatcat atttttgtat tcatttatga tatgttctgc
     9841 atttacataa aatctttctc ctgctggtgt taacccattt aacctgcctt tatacctttc
     9901 aaataaatat acatcttcac tttcttcaaa attttttata atttgactta atgctggttg
     9961 agatatgtga agtgtcttag atgctattga taaattaaaa ccagatttca ctatttcaac
    10021 aaaatatttc aactgtttta tatccatttt aaaccccctt ccccaaaagt ataatttaga
    10081 ttatattttt tcttctaatg atattttata ggaaaatcaa cataatttca ttaatatttt
    10141 aacaaaatat ttttctaaat ctactataaa tttttatcct ataaattttt cttatacact
    10201 atataaaaaa ttagacttag acaaaacgct tttttcgccg taatctataa ttagaaacag
    10261 gaaaacctaa agcattagga ataaaagtaa ttgaaatact taaaaacaag cttgtattaa
    10321 aaaagtactt tattatagtg ttccctaatt tctttattca gaaaattttt aattatcatt
    10381 caagaaaggt aactattaga tatgaaagat gtagtaatcg tatcagcagt cagaacacct
    10441 ataggaagtt ttggaggtgt atttaaaaat acttcagctg ttcaacttgg aactatcgct
    10501 gttaaagaag cgatatcacg tgtaagactt aatttatctg aaatagatga agtaataatt
    10561 ggaaatgttc ttcaaacagg gcttggacag aatgttgcta gacaaattgc tataaatgca
    10621 ggtataccaa attctgttcc aagctacaca gtaaataaat tatgtggttc agggcttaaa
    10681 agtgtccagc tagctgccca atcaatcaca tctggtgaaa atgatgtggt aattgcaggt
    10741 ggtactgaaa atatgagcca agctccttat atcgttccaa ctgctcgctt tggtagtaaa
    10801 atgggtgaca taaccatggt agatagtatg ctaacagatg gccttattga tgctttcaat
    10861 cagtatcata tgggaataac tgcagaaaat attgcaacta aatttgaatt tactagagaa
    10921 atgcaagata aattggcatt agaaagtcaa aataaggctg agaatgctat aaaaaacaac
    10981 cgctttaaag aagaaatcgt tccagtagat attttaatac gtcgaggaaa aatagaaact
    11041 attgataaag atgaatatcc taaattaggt atgacatttg aaggtttagc taaacttaaa
    11101 cctgcattca aaaaagatgg tactgtaaca gctggaaatg cctcaggtat taatgatggt
    11161 gcggctatgt taatactaat gagccaacaa aaagcagacg aactaggtat tagaccactt
    11221 gctaaaataa aatcctatgc ttcagctggt gttgaacctg aagtcatggg tactggtcca
    11281 atccctgcaa ctagaaaagc actgaaaaaa gctggactta gcatcaatga tatagactta
    11341 atagaagcaa acgaagcgtt tgctgcccaa gcattagctg ttaaaaatga acttcaaata
    11401 gattcatcaa agttaaatgt taatggtggt gcaatagcat taggacatcc aataggagca
    11461 agtggagcta gaatacttgt taccttaatt tatgaaatgc aaaaacgtaa agttgaaact
    11521 ggacttgcaa cactttgtat tggtggtggt caaggaatat caatggtggt ttcacgatag
    11581 gaggaaatat gaataaaata gttagcattg atgaagctct atctcatgta aaagatggag
    11641 atacaataat ggttggtgga ttcatggcca atggttcacc agaaaattta attgattatt
    11701 tatgtagtaa aaatataaaa gatttgacac taatttgcaa tgatactggc tttattgaca
    11761 aaggagttgg caaaatggtt gtaaataagc aatttaaaaa gataattgct tctcatgtag
    11821 gattaaataa agaaactgga agacaaatga acaacaatga aacagatgtt gagttagttc
    11881 ctcagggaac tcttgctgaa caaatacgtg cagctggtta tggtctagga ggtatactca
    11941 caccgactgg tattggtact cttgttgagg agggaaagca aaaaattgtt gtcgatagca
    12001 aagaatacct tcttgaaaaa ccaatttatg cagatgttgc tcttctattt gcatcaaagg
    12061 tcgataaagc aggtaatcta gtttataaag gctctatgaa caattttaat aatttaatgg
    12121 catctgctgc caaaattaca atagttgaag cagatgaaat cgttgaaatt ggtgatattg
    12181 acccaaatga agttaataca ccaggtattt ttgtgaatta catcgttgaa ggaggtaatt
    12241 tataatggat aaattagaaa tgcaagaata tattgcaaat agagtatcta aagaattaaa
    12301 agacggagcc gttgtaaacc ttggaatagg tctaccaacc aaagtagcaa attatattcc
    12361 ggataatgta aacgttatct tacaatctga aaatggattt ttaggtttag gttcagccga
    12421 agatggaaat tcaagtgatg aaactattgt aaatgcaggt ggtcaaccag ttactatact
    12481 tcctggagga tgtttctttg atagtgctac ttcttttgga ataatcagag gaggtcatgt
    12541 tgatataact gttcttggcg cacttcaggt tgacaaatat ggcaatatag caaactatat
    12601 gattccaggt aagatggttc caggtatggg tggagctatg gacctagtaa ctggagctaa
    12661 aaaagttatt gtagcaatgg aacatacttc aaaaggttct gcaaaaatat taaataattg
    12721 tactcttcca cttactgcaa caaatgctgt agatttgata gttactgaaa tgggagttat
    12781 ggaagtaaca tcagatggaa ttttacttaa aaaaataaat ccagctttca cattagatga
    12841 tgttatttct gctactgaag ctcctttaat attgtcagat tcattaaatg gaaaaatatc
    12901 tgttgtttaa aataattaaa actagaaaat aaaaatctct tagacgtatt acatataaat
    12961 ttgtattgct taaaatatta atataaaaat aaaataaaat tggaggaaat gaaaatggtt
    13021 aaagataaag ttgtattcgt aacaggagct gcaagtggaa taggtaaaca aatagctgaa
    13081 tcgttcttaa aaaatggtgc taaagtaatg ttctctgata taaatcaaga atctttaaat
    13141 aataccataa cagagttaca aaaaaaaggt tatgattgca tgagtgtaaa gtgtgatgta
    13201 actaaggaag aagaaattaa tcacgctata gacaaaactg ttgaaaagta tggcagatta
    13261 gatatattaa taaacaatgc tggacttcaa catgtttcta tgatagaaga tttcccaact
    13321 gataaatttg aatttatgat aaaaataatg ctgacagcac cttttatagc tactaaaaaa
    13381 gcatttccta taatgaaaaa acaaggcttt ggtcgtataa taaatatggc ctcaatcaat
    13441 ggtgtaatag gatttgctgg aaaggctgct tataactcag caaaacatgg acttattgga
    13501 ctaacaaaag ttgctgctct tgaagctgcc gattctggta taacagttaa tgctttatgc
    13561 cctggatatg tagatactcc acttgtcaga ggtcagttca atgacctttc aaaaactcgt
    13621 aatataccat tggaaaatgt cttagaggaa gttttatacc cacttgtacc acaaaaacgc
    13681 ctattagatg ttcaagaaat tgccgactat gctatgttct tagcaagtga taatgctaag
    13741 ggtattacag gacaagcttg cttactagat ggaggatata ctgcacaata gttattatat
    13801 ttagggcttg aagaaagtat tcttcaggtc cttctactaa ggagggatat ttatgagtat
    13861 tatcgcacca attggtataa ttattggtat catagctatt atatattttt cagttaaaga
    13921 aattcatata actatagctg ctccaatagc aactttaata gttgttattt taaataaaat
    13981 ggatgttgta acgtcaatgc taggtgctga caaaaacaat tatatgggtg cacttggaaa
    14041 ctatataatg agttattttg caatattctt attaggctca atacttgcta aatttatgga
    14101 agaaagtgga gctactgtat caatagctga ttttatttta aataaatttg gctctaatca
    14161 tccttataga gttttagttg ctatatttat agtaagtttt atattaacgt atggtggtat
    14221 aagcctattt gtagttatgt ttgcggtcat tccacttgca agaactctat ttaaaaaact
    14281 tgatatttct tggaacctta ttcagatacc actttggctt ggtattgcaa caattactat
    14341 gactataatt cctggaacac cagccattca aaatgttata cctattcaat atctaaatac
    14401 gtctcttact gcagctacta taccaagtat tgtaggtagt ataggttgtg ctacatttgg
    14461 acttgtctat atgaaatatg ctctaaacaa aagtattaga aaaggtgaaa cttatgcaac
    14521 ttacacttca gaattagaag aagaatcttt agatagagaa ttaccaggat tttttgcaag
    14581 tatttttcct ctattagcac tcgtaattat agctataact ggaagtactt ttggttcaga
    14641 atttatgaaa aaaaatgtaa tttacatagc tttaatagtt gcaattcttt tatctgcttt
    14701 tttattccat aaatttctat catctaagat acagacattg agcataggtg ctagtggttc
    14761 tataggtcct atatttgcta catcttctgc agttgcattt ggagcagtaa taatggctgc
    14821 acctggtttt gatgtattta gcaaacttat aatgtcaata ccaggtagtc cacttataag
    14881 tcttactgtt ttgacttcaa caatgtcagc aataacaggg tcctcttctg gtgcattagg
    14941 aatagtaatg ccaaactttg cagattatta tttaagtact ggtctaaatc cagaattaat
    15001 tcaccgtgtt gctacaatag cctcaaatat actaactata gttccacaaa gtggtgtttt
    15061 tcttacattc ttaagcttat ctaagttaac acataaaact ggatttaaag aaactttcat
    15121 tgtagttgca gttggttcac taatagcaga aattattgta attacattag gattactaat
    15181 gtattaatat aaaacaaatt aaaattcata atatgaaagg tggtgtctca aagtgaactt
    15241 tttacttaat gagacactct ttttatatga aataacataa gcctatcatt tcaacaataa
    15301 aaaagaacct tatctctatt ttgagacaga ccctttttat ttcttaaaga tttaaataat
    15361 tataatttgt tgctaatacg aaagcatcta ctgaataaat ttaaccaaat aaaaaaaaat
    15421 ttatcataac tataaattta cgttatggaa ttattataaa aatattattt tctctaacta
    15481 agtaattcca tactatacag gcttttaata caaattgtca aacacactga aatataccta
    15541 tttattccat atatatcttt tttacatatc tttacagtaa aaaaagtctt aatcttatgt
    15601 tagtatagat tcacgggtaa ccccctacac taaaggttac aaatcagtaa catttttaga
    15661 atttttagat taagaggtgt ttaatgatga gaagaaatat accaacaaaa ttaaaaacta
    15721 tattagcttt aggagtgtta actttagcaa cagcttcaag tgctgttact gcaagtgctt
    15781 catcacttga aaataatgta aatataagta acaaaagttt agtatatagt aatactaaat
    15841 acaagttttc tgcaaaacca aattgttctg taaaaccaga acttaagcct gataaagata
    15901 actcttgtaa ggataagaat cataatgaca agaattgcaa caacactaat aaacctgagg
    15961 acaacaataa ttcagactct actaataagc ctgataacaa taaacctgag tctaataaac
    16021 ctgaagacaa caataattca ggctctacta ataaacctga taataataaa cctgagtcta
    16081 ataaacctga agacaacaat aattcaggct ctactgataa acctgataac aataaacctg
    16141 agtctaataa acctgaagac aacaataatt cagactctac taacaaacct gatgataata
    16201 acaactcagg ctctacaagt gaaagttttt cagcttacca aaaagaagtt gttgacttag
    16261 taaatataga aagagctaaa gctggattaa atcctcttac tcttgattct tctatatcaa
    16321 atgttgctac aaaaaaatct caagatatga ttgataacaa ctatttttca cacaattctc
    16381 caacttatgg ttctccattt gacatgttga aaaaatttgg aataagctat aagacagcag
    16441 gtgaaaatat agctatgggt caaaaaactc ctaaagaagt tgtaaacgca tggatgaatt
    16501 ctgaaggtca cagaaaaaat ataatgaatc caaatttcag taaaataggt gttggagtag
    16561 cacaaaaaag tggtggttca atttattgga cacaaatctt tgtaggataa aatactcttt
    16621 ttccatacat atcaaaagag tatctctaag tgataaaaaa cacaaatgag atactctttt
    16681 gtatctattt taaaattatc aaatccaaat atacatacta taaatattat ttgttctctt
    16741 aattttagtg tgtagagcaa tatataaaaa gtattggcaa gatgaaaatg gaaaacttaa
    16801 aaaagatatt taataggtaa aaacaaaatc ttaatatctt cataaaaaaa ggctgtctca
    16861 aaatagagat aaggcctttt tcattgttga aatgattaaa atatatttga tttcatacaa
    16921 aaagagtgcc tcatgaacta aaaagctcac tttgagacac tctcttttat caattctata
    16981 taagcattat aatactttaa tattattcag ctaatttttt gtatccttca tatctttctt
    17041 tagcatcagc ttcagcttta gcaaataatc catcagcttc ctctgggaat tgtttagcta
    17101 tagcagaata tcttacttgt gcaagtatga aatctttgaa gcttgcagtt ggttcttttg
    17161 aatctaaagt gaatgggttt ttaccttcag cttttacttc tggattgaat ctgtataaat
    17221 gccagtatcc gcaagcaaca gcttgtgctt cattagctac agttcttccc ataccttctt
    17281 ttaatccatg gtttatacat ggagcataag ctattattag agatggccca tcatgttttt
    17341 cagcttctaa aacggctttg ataaattgat ttttatcagc acccatagca acttgagcta
    17401 catatacgtt tccatatgtc atagccatca ttcctaaatc tttctttcta gattttttac
    17461 ctgaagcagc aaacttagcc atagcagcag ctggagtagc tttagaagct tgacctcctg
    17521 tatttgaata tacttctgta tcaaatacaa gtacgtttac atcttcacca gatgcaagaa
    17581 catggtctaa tccaccataa ccgatatcat atgcccaacc gtctccacct agtatccatt
    17641 gagatctctt aactagataa tcttttctat cttttatagc ttttactaat tctttagctt
    17701 tttcatctgt acaatcacaa gctggttttt ctaataattc aacaacctta gcacttgcta
    17761 ctttagaagc ttctccatca tttctagaat ctaaccactc tgtaaatact gctttagcat
    17821 cttcacagat atccatagaa actaactctg tcatagcatc tactatttta tttcttattt
    17881 gcttaacagc tgtgtacata ccaaatccat attcagcatt atcctcgaat aaagaatttg
    17941 cccaagatgg acctttacct tcatggttac aagtataagg aattgatggt gcagaagctc
    18001 cccatataga agaacatcca gtagcattag ctatcatcat tctatctcca tataattgtg
    18061 taactacttt aatgtacgca gtttctccac atccagcaca tgctcctgaa aactccatta
    18121 atggttgtct aaattgactt cctttaacag tatttgcagg cataacatca acttttggag
    18181 ctacttcatc aggatttact gcaaatgccc aattatctaa ctctgtatca agttgagtat
    18241 ctattggctt cataactaaa gctttttctt tagctggaca tatgtcagca cagtttccac
    18301 atcctgtaca gtcaagtgga ctaacttgaa ttctatattt taatccttct aatcctttac
    18361 ctaatgcttt tttagcttca aatccttctg gagcattagc taattcttct tcagtaacta
    18421 atactggtct tatacatgca tgaggacata taaaagaaca ttggttacat tgaatacagt
    18481 tatctattat ccattcagga acatcaacag ctataccacg tttttcataa gctgcagtac
    18541 cacaagggaa tgttccatct tctataccat tgaatgtact tactggtaag ttgtttcctt
    18601 cttgtgcagt cattggtctt agtatatttt ttataaattc tggttcttta acttctcctt
    18661 tatctgcatc aacagcattt tcccaagaag ctggaacttc aactttaact aaagcattta
    18721 ttcctgcatc aacagcagca tagttcatat taactatttt ttcacctttt ttaccataag
    18781 ctttaactat agaatctttt aagtatttaa cagcatcttc ttctggtatt atttcagcta
    18841 atttaaagaa tgcagattgc attatcatgt ttattctgtt tccaagacct atttcttgtc
    18901 ctagtttaac agcgttaact gtatagaatt ttatatcatt tttagctata tattgtttca
    18961 tatgagctgg taaatgttct tcaagtcctg cttggtccca tatagtgtta agtacaaatg
    19021 taccaccttt tttaagacct tttaataaat catattgata aacatatgat tgtttatgac
    19081 aggcaatata atcagcttca tctattaaat aagtagctct tattggagta tcaccaaatc
    19141 ttaagtgaga catagttata ccaccagatt ttttagagtc ataatcaaag taagcttgag
    19201 catatttttc agtatggtca ccgattattt tgatagcttg tttattagct ccaacagtac
    19261 cgtcagaacc taatccccag aacttacatc ttatagttcc tttagaagct atttttattg
    19321 gctcagatgg agttaaagaa gtattagtta catcatcaac tatacctact gtaaatccat
    19381 ttttaggttg ttctgaaact aagttatcaa aaacagtttt tatatctgaa ggagtagtat
    19441 cttttgaacc taatccgtat cttccaccta ttatcatagg agcattttct tttccataga
    19501 atacatcacg tacatctaag tataatggtt caccagttga acctggctct ttagttctat
    19561 caagtacaca tattctttca acagtagatg gcatagcatc taagaaatgt ttcattgaga
    19621 atggtctata taaatgaact ttaactaaac catatttttc tcccttagca tttaagtaat
    19681 ctatagtttc ttctattgtt tctgttactg aacccatagc tattaatacg tatttagcat
    19741 cttctgctcc atagtaatca aataaactat gttttctacc tgttaaatta ctcatttttt
    19801 ccatgtattt ttcaactata cctactatat tttgatagta tttattagaa gcttctctag
    19861 tttggaaata tatatctggg ttttgagcag taccacgagc aactggatga tttggagata
    19921 aagcattatc tctaaatgct tgaactgctt caaagtttaa taaacttgca taatcttcat
    19981 tttctagtaa ttcaactttt tggatttcat gtgaagttct gaatccatca aagaaatgta
    20041 taaatggtaa tctaccttct attgcagcta aatgtgcaac aggtgctata tcagctactt
    20101 cttgaactga accagaagct aataatacac atccagtttg tctagcagcc ataacgtctt
    20161 ggtgatcccc aaatattgat aacgcttgag atgctaaagc acgagcactt acatggaata
    20221 ctcctggtaa taactctcct gcaactttat acatgttagg tatcattaat aataaacctt
    20281 gagatgctgt aaaagtagaa gttaaagctc ctccttgtaa agaaccgtgg aatgttcctg
    20341 atgcacctgc ttctgactgc atttcaacaa cattaactgt ttgtccaaat atattttttc
    20401 ttccttgtga tgcccactca tcaactactt cagccatagt tgaagatggt gtgattggat
    20461 atatagctgc tacatctgta aacgcatagg caacatgagc tgcagctgta tttccatcaa
    20521 gtgttttcat aaacttagcc ataatatgta tcctccttga tagctacaat tgtacttgtt
    20581 tataacaagt ctattttttt atatttacat ataatttaca caacaaaaat ataaacacac
    20641 atatagtcgc gcaaatactc tatcttctaa tataatacta cagattagat aaaattcctt
    20701 tgaaaattgt aaattaatta catatttaag tagatttttt ttaaaattaa atatgttaag
    20761 tttttttcat a
//
LOCUS       DAMKNB010000065        20728 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.067, whole genome shotgun sequence.
ACCESSION   DAMKNB010000065 DAMKNB010000000
VERSION     DAMKNB010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 20728)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20728)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20728
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.067"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            370..681
                     /gene="rpsJ"
                     /locus_tag="PC494_002632"
     CDS             370..681
                     /gene="rpsJ"
                     /locus_tag="PC494_002632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HDF3913123.1"
                     /translation="MAKNEKIRIRLKSYDHKLLDFSAGKIVETAKKAGSQVSGPVPLP
                     TEKQVVTILRAVHKYKDSREQFEIRTHKRLIDIANPTPKTVDSLMRLDLPAGVDIEIK
                     L"
     gene            773..1402
                     /gene="rplC"
                     /locus_tag="PC494_002633"
     CDS             773..1402
                     /gene="rplC"
                     /locus_tag="PC494_002633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HDF3913124.1"
                     /translation="MKGILGKKVGMTQIFTDKGVVIPVTAVEAGPMVVTQIKTVDKDG
                     YNAIQIGFEDAKEKALNKPKKGHLAAANVLKKHLKEFRVDSVEGYTVGQEIKADVFEA
                     GAKIDVTGISKGKGFQGPIKRHGQSRGPETHGSRYHRRPGSMGACSYPGRVFKNKKLA
                     GHMGSVKVTVQNLEVVKVDADKNLILVKGAIPGAKGSVVTIKEAIKVSK"
     gene            1432..2055
                     /gene="rplD"
                     /locus_tag="PC494_002634"
     CDS             1432..2055
                     /gene="rplD"
                     /locus_tag="PC494_002634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001127258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HDF3913125.1"
                     /translation="MPKLNVLNVSGQNVGEIELSDSIFGVEVNGHVLYEVVKNQLANK
                     RQGTQSAKTRAEVRGGGRKPWKQKGTGRARQGSTRSVQWVGGGVAFAPKPRSYKYTLP
                     KKVRRLAMKSALSSKVQNSEVIVLDALNMDAPKTKEFAQILNNINAAKKALVVIADKN
                     DNVIKSARNIEGVQTALVNTMNVYDILKYDSFIITTDAVKKVEEVYA"
     gene            2055..2345
                     /gene="rplW"
                     /locus_tag="PC494_002635"
     CDS             2055..2345
                     /gene="rplW"
                     /locus_tag="PC494_002635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001205558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HDF3913126.1"
                     /translation="MTNPHDVIIRPVVTEHSMAEMGEKKYTFVVAKDANKTEIKKAVE
                     KVFGVSVDKVNTLNYDGKVKRMGRTQGRTSSFKKAVVKLTADSKEIEFFQGM"
     gene            2375..3205
                     /gene="rplB"
                     /locus_tag="PC494_002636"
     CDS             2375..3205
                     /gene="rplB"
                     /locus_tag="PC494_002636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HDF3913127.1"
                     /translation="MAIKKFRPTSPALRQMTVLVSDEITCNQPEKSLLVNLKKNAGRN
                     VHGRITVRHRGGGQKRKYRIIDFKRDKDGIPAKVATIEYDPNRTANIALLNYADGEKR
                     YILAPVGINVGDTILSGLGADIKPGNCLALKDMPVGTIIHNIELKPGKGAQLVRSAGV
                     SAQLMAKEGKNALLRLPSGEMRLVSINCKATIGQVGNIEHGNVVIGKAGRKRHMGIRP
                     TVRGSVMNPNDHPHGGGEGRSPIGRPSPVTPWGKPALGYKTRKKNKASNKLIVSRRTK
                     "
     gene            3240..3521
                     /gene="rpsS"
                     /locus_tag="PC494_002637"
     CDS             3240..3521
                     /gene="rpsS"
                     /locus_tag="PC494_002637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003454422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HDF3913128.1"
                     /translation="MSRSTKKGPFVHARLLKKIEAMNASGNKEVIKTWSRSSTVFPQM
                     VENTIAVHDGRKHVPVYITEDMVGHKLGEFVPTRTFKGHKDDEKSNKRK"
     gene            3553..3888
                     /gene="rplV"
                     /locus_tag="PC494_002638"
     CDS             3553..3888
                     /gene="rplV"
                     /locus_tag="PC494_002638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018590372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HDF3913129.1"
                     /translation="MEAKATAKYVRVSPRKAGQICDLVRGKNVDEALAILKFTPRGAA
                     SIIAKVVKSAKANAENNHEMDTEKLYIASIVANQGPTMKRFMPRAMGRATTIRKRTSH
                     IEVVVKEKK"
     gene            3911..4726
                     /gene="rpsC"
                     /locus_tag="PC494_002639"
     CDS             3911..4726
                     /gene="rpsC"
                     /locus_tag="PC494_002639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HDF3913130.1"
                     /translation="MGQKVNPHGLRVGVIKDWDSRWFATDKKEFGNLLLEDHNIRKFL
                     KKRLYSAGVAKIEIERSANKIKMDLHVAKPGVVIGRAGAGIEALKAELEKMTKKTIIV
                     NIVEVRSTDKNAQLVAENIALAIERRVAFRRAMKQAIQRAMKSGAKGIKVSASGRLGG
                     AEMARTEGYSEGNVPLQTLRADIDYGFAEADTTYGKIGIKVWICNGEVLPTRDGVNPR
                     EESRKSDRRDNKRDNRRNDRRGNDRRGNDNRGNYRGQRPQGGSRPQRTENKGN"
     gene            4762..5193
                     /gene="rplP"
                     /locus_tag="PC494_002640"
     CDS             4762..5193
                     /gene="rplP"
                     /locus_tag="PC494_002640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HDF3913131.1"
                     /translation="MLMPKRVKRRRVHRGSMAGQAHKGNKVTYGEFGLVALEASWITS
                     NQIEAARIAMTRYIKRGGKVWIKIFPHKPVTRKPAETRMGAGKGSPEYWVAVVKPGRV
                     MFELAGVSEDKAREAMRLAAHKLPIKCKFVKKEDLEVKGGE"
     gene            5195..5398
                     /gene="rpmC"
                     /locus_tag="PC494_002641"
     CDS             5195..5398
                     /gene="rpmC"
                     /locus_tag="PC494_002641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005810148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HDF3913132.1"
                     /translation="MKAKELRDLTSEELMNKLNDFKSELFSLRFQLATGQLENTARIK
                     FVKKDIAKVKTVLAERKLYETRA"
     gene            5422..5676
                     /gene="rpsQ"
                     /locus_tag="PC494_002642"
     CDS             5422..5676
                     /gene="rpsQ"
                     /locus_tag="PC494_002642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018590376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HDF3913133.1"
                     /translation="MERGRRKVRIGRVVSDKMDKTIVVAVEEFVRHPLYNKRVKRTKK
                     FKAHDEKNICNIGDRVKIMETRPLSKDKRFRLVEVVEKVK"
     gene            5702..6070
                     /gene="rplN"
                     /locus_tag="PC494_002643"
     CDS             5702..6070
                     /gene="rplN"
                     /locus_tag="PC494_002643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007885948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HDF3913134.1"
                     /translation="MIQQESRLRVADNSGAKELLCIRVLGGSKRRYGNIGDVIVATVK
                     SATPGGVVKKGKVVKAVIVRSKQGVRRNDGSYISFDENAAVIIKDDKTPVGTRIFGPV
                     ARELRDNEFMKIVSLAPEVL"
     gene            6094..6399
                     /gene="rplX"
                     /locus_tag="PC494_002644"
     CDS             6094..6399
                     /gene="rplX"
                     /locus_tag="PC494_002644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HDF3913135.1"
                     /translation="MRVKKGDTVVVIAGKDKGKKGSVLKVYPKTSKVLVEGVNVITKH
                     QKPSAMNQQGGIINKEAPIHISNVMPFDPETGKGVRVRYEVKDGNKVRVSAKSGKEL"
     gene            6429..6971
                     /gene="rplE"
                     /locus_tag="PC494_002645"
     CDS             6429..6971
                     /gene="rplE"
                     /locus_tag="PC494_002645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018590379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HDF3913136.1"
                     /translation="MASRLQEKYMKEVAPALMEKFGYKNVMEIPKLNKIVINMGIGDA
                     RENPKGLEKGVEELEMISGQKPVITKARKSVANFKLREGMPIGTKVTLRADKMFYFMD
                     KLVSVSLPRVRDFRGVNPNAFDGRGNYALGVKEQLIFPEIEYDKIDKVRGMDIIFVTT
                     AKTDEEARELLKLLGMPFSK"
     gene            6989..7174
                     /locus_tag="PC494_002646"
     CDS             6989..7174
                     /locus_tag="PC494_002646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type Z 30S ribosomal protein S14"
                     /protein_id="HDF3913137.1"
                     /translation="MARKAMVVKQQRKQKYATREYTRCTICGRPHSVLKKFGICRICF
                     RELAYKGQIPGVRKASW"
     gene            7207..7605
                     /gene="rpsH"
                     /locus_tag="PC494_002647"
     CDS             7207..7605
                     /gene="rpsH"
                     /locus_tag="PC494_002647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012158382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HDF3913138.1"
                     /translation="MTMTDPIADMLTRIRNANVVKHETVDVPASNMKKELARILLEEG
                     FIRGYDVIEDGKQGIIRIQLKYGQEGERVITGLKKISKPGMRVYAANHEIPKVLNGLG
                     ISVISTSKGILTDKQARKENVGGEVICYVW"
     gene            7636..8178
                     /gene="rplF"
                     /locus_tag="PC494_002648"
     CDS             7636..8178
                     /gene="rplF"
                     /locus_tag="PC494_002648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HDF3913139.1"
                     /translation="MSRIGVKPIIIPAGVEVTIAEGNLVTVKGPKGTLTKQLSAELNI
                     KKEENTIMVERPTDNKKHRSLHGLTRTLLDNMVVGVNTGFEKKLELKGVGYRAQKQGK
                     KLVMNLGFSHPVEMEDPEGITVEAPNQTELIVKGIDKQLVGNYAAKIRAWRKPEPYKG
                     KGIKYVDEVIRRKEGKTGKK"
     gene            8214..8582
                     /gene="rplR"
                     /locus_tag="PC494_002649"
     CDS             8214..8582
                     /gene="rplR"
                     /locus_tag="PC494_002649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HDF3913140.1"
                     /translation="MLKKADKNANRLQRHKRVRRKISGTSQRPRLCVFRSANNIYAQI
                     IDDTKRVTLVAASSLEAEVKSAVNHTGNKEAAKKVGELVAKKAVEKGITEVVFDRGGY
                     LYHGRIQELAEGAREAGLKF"
     gene            8603..9112
                     /gene="rpsE"
                     /locus_tag="PC494_002650"
     CDS             8603..9112
                     /gene="rpsE"
                     /locus_tag="PC494_002650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011109776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HDF3913141.1"
                     /translation="MLRRKPIDAGQLDLQEKVVEVRRVTKVVKGGRNFRFAALVVVGD
                     ENGHVGIGAGKAMEVPDAIKKAVEDAKKNLIVVPIVGTTIPHEVRGHFGAGNILIMPA
                     VEGTGVIAGGPARAVLELAGLKDVRAKSLGSNNPRNMVNATIEGLNSLKTVEDIAKLR
                     GKKVEELLG"
     gene            9127..9312
                     /gene="rpmD"
                     /locus_tag="PC494_002651"
     CDS             9127..9312
                     /gene="rpmD"
                     /locus_tag="PC494_002651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HDF3913142.1"
                     /translation="MAKLQIKLVRSVIGTTPNQKKNVEALGLRKREQVVVKEDNAQTR
                     GMINKVSHLLEVTEIAE"
     gene            9345..9788
                     /gene="rplO"
                     /locus_tag="PC494_002652"
     CDS             9345..9788
                     /gene="rplO"
                     /locus_tag="PC494_002652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000766080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HDF3913143.1"
                     /translation="MKLHELKPAEGAVRAKRRLGRGTATGQGKTAGRGQKGQWSRSGG
                     GVRVGFEGGQMPLARRLPKRGFNNIFKKVYTEVNVEVLNRFENGTEITAELLKSTKTI
                     SKIGKDGIKILGEGNLEKALTVKAAKFTASAQEKIEKAGGKAELV"
     gene            9832..11100
                     /gene="secY"
                     /locus_tag="PC494_002653"
     CDS             9832..11100
                     /gene="secY"
                     /locus_tag="PC494_002653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HDF3913144.1"
                     /translation="MLSKLKQAWKIKAVRKKVMYTLMMIVIFRIGTTIPVPGIDTSII
                     QKMVGGNSLLSLYNMFTGGAFSNFSLFALGISPYITASIIIQLLTVGFESLAELQKSG
                     EEGKKKINKYTKYTALALAVVQALGITLGIVRSALISNSVFFITTVVITLVSASMLVM
                     WIGDKITEKGIGNGSSVIIFAGIISRIPTDVIKISQQVKSGEVAPWVIVILAVVILLT
                     VTGVTFIQEATRKIPVQYAKRVVGRKMYGGQSSHIPMKVNQSGVMPIIFASSLLAFPQ
                     TIAMFMGPNAQAFVQKYLSMATEQGFWTYRSIEILLIIFFSYFYTTVSFNTEDISKNM
                     KNNGGFIPGIRPGEPTMDYLNRILTRLTLAGATFLAIIAMVPALTTHYMKVNMSLAGT
                     SLLIVVGVALELKRQLESNLVMRSYQGFLK"
     gene            11117..11767
                     /locus_tag="PC494_002654"
     CDS             11117..11767
                     /locus_tag="PC494_002654"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HDF3913145.1"
                     /translation="MRIILLGPPGAGKGTQAAGIVEKYNIPHISTGDIFRKNIKEGTE
                     LGKKAKEYMDQGLLVPDELTVGLVTDRISQEDCKNGFMLDGFPRNVAQGEHLDIFLKN
                     AGISLDKVVNIEVDKSILVSRAVGRRICKSCGATYHVEFNPPKVEGVCDVCQGELYQR
                     ADDNEETVSKRIQVYLDETKPLVDYYSKQGIIADIKGDQAIDKVFEDIVAALGSGK"
     gene            11768..12514
                     /gene="map"
                     /locus_tag="PC494_002655"
     CDS             11768..12514
                     /gene="map"
                     /locus_tag="PC494_002655"
                     /EC_number="3.4.11.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I methionyl aminopeptidase"
                     /protein_id="HDF3913146.1"
                     /translation="MIILKSKKEIELLREAGKIVADTHEVLRKAISPGISTLELDKIA
                     EENIRKYNAEPSFKGYGGFPGSICASINREVVHGIPGETILQEGDIVSLDIGAYYKGY
                     HGDSAKTHGVGMISEEDRKLIEVTRESFYEGIKFAKLGYRLSDISHAVQTHVEKHGFS
                     VVRDLVGHGVGANLHEDPQVPNYGLPGKGPRLREGMVIAIEPMVNAGRYHVKTLSDGW
                     TTVTIDGKKSAHYEHTIAITEHEPLILTKL"
     gene            12536..12805
                     /locus_tag="PC494_002656"
     CDS             12536..12805
                     /locus_tag="PC494_002656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KOW domain-containing protein"
                     /protein_id="HDF3913147.1"
                     /translation="MLSDNLSIGQVVKVSLGRDKGNLFFVVKIINNEYVLIADGKKRK
                     LDKPKLKKVKHLKKYNFINDEVRKRVVSGQEITDSFLRAELTKLN"
     gene            12843..13061
                     /gene="infA"
                     /locus_tag="PC494_002657"
     CDS             12843..13061
                     /gene="infA"
                     /locus_tag="PC494_002657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001029884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HDF3913148.1"
                     /translation="MAKKDVIELEGTVSEALPNAMFKVKLENGHEILCHISGKLRMNF
                     IRILEGDKVNVELSPYDLTRGRITWRKK"
     gene            13097..13210
                     /gene="rpmJ"
                     /locus_tag="PC494_002658"
     CDS             13097..13210
                     /gene="rpmJ"
                     /locus_tag="PC494_002658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003720928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HDF3913149.1"
                     /translation="MKVRPSVKPICEKCKVIKRKGKVMVICENPKHKQKQG"
     gene            13363..13734
                     /gene="rpsM"
                     /locus_tag="PC494_002659"
     CDS             13363..13734
                     /gene="rpsM"
                     /locus_tag="PC494_002659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005810116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HDF3913150.1"
                     /translation="MARIAGVDLPREKRAEIGLTYIYGIGKATANEILAKAEINPDTR
                     IKDLSEDQVNELRKVIDDDFLVEGDLRREIALNIKRLRDIKCYRGIRHAKGLPLRGQR
                     TKTNARTRKGPRKTVSRKKKK"
     gene            13770..14168
                     /gene="rpsK"
                     /locus_tag="PC494_002660"
     CDS             13770..14168
                     /gene="rpsK"
                     /locus_tag="PC494_002660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006440523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HDF3913151.1"
                     /translation="MAKPKKKVTRIRRRERKNIERGHAHIQSTFNNTIITLTDVHGNA
                     ISWASSGQLGFKGSRKSTPFASQMAAETAAKAAMEHGLKSVEVFVKGPGSGREAAIRA
                     LQATGLEVTMIKDVTPIPHNGCRPPKRRRV"
     gene            14200..14823
                     /gene="rpsD"
                     /locus_tag="PC494_002661"
     CDS             14200..14823
                     /gene="rpsD"
                     /locus_tag="PC494_002661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HDF3913152.1"
                     /translation="MARYTGASCRQCRREGMKLFLKGDRCYTDKCAIVKRNYAPGQHG
                     QGRKKVSNYGLQLREKQKVKRIYGVLETQFRNLYERAENMPGKAGENLLSLLERRLDN
                     VVYRMGLASSRKEARQLVTHGHFTLNGNKVDIPSLIVKVGDVIEVKEKSRSSAKFKNL
                     VEVNSRIAPKWLEANVEGMTAKVVGVPTREDIDLEIAEHLIIELYSK"
     gene            14901..15848
                     /locus_tag="PC494_002662"
     CDS             14901..15848
                     /locus_tag="PC494_002662"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HDF3913153.1"
                     /translation="MIEIEKPKVDIVELSEDYRYGKFVIEPLERGYGITIGNALRRIL
                     LSSLPGVAVNAIKIDGVLHEFSTIPGVKEDVTEIILTLKELSATIDGEGSRTLKIEAQ
                     GPCSITGADIICPPDVEILSKDLAIATLDDNAKLNMEIFVDKGRGYVSAEENKTENVP
                     IGVLPVDSIYTPVEKVSYHVENTRVGQKTDYDKLVLEVWTNGSINPQEGISLAAKVLV
                     EHLNLFIDLTEHVSSVEIMVEKEEDQKEKVLEMTIEELDLSVRSYNCLKRAGINTVEE
                     LANKSEDDMMKVRNLGKKSLEEVIQKLEELGLGLKPSEE"
     gene            15869..16210
                     /gene="rplQ"
                     /locus_tag="PC494_002663"
     CDS             15869..16210
                     /gene="rplQ"
                     /locus_tag="PC494_002663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003357477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HDF3913154.1"
                     /translation="MAKYRKLGRETAHRNLMLRNLVTCLLRSGRIETTVTRAKETRRM
                     AEKMITLAKRGDLHARRQVLAYVMDETVVNNLFTDLAPKYAERNGGYTRIIKIGPRKG
                     DAAEMAFIELV"
     gene            16330..17163
                     /locus_tag="PC494_002664"
     CDS             16330..17163
                     /locus_tag="PC494_002664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HDF3913155.1"
                     /translation="MDNIVKVNNISFEYITDEAKLKAIDNLSLDVKKGEFVAIIGHNG
                     SGKSTLSKNLNAILMPTEGNILIDDMDTKEEERLWDIRQTAGMVFQNPDNQIVATIVE
                     EDVAFGPENLGIEPKEIRRIVEESLKSVGMYDLRDRQPHLLSGGQKQRVAIAGIIAMR
                     PKCIIFDEATAMLDPSGRKEVMKTIKRLNKEENITVIHITHFMEEAVEADRVVVMEKG
                     KKILEGTPREVFSKIKMLKEIGLDVPCMTELSSLLIEEGINISSDILTVDEMVMELCQ
                     L"
     gene            17151..18017
                     /locus_tag="PC494_002665"
     CDS             17151..18017
                     /locus_tag="PC494_002665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HDF3913156.1"
                     /translation="MSIIVKNLTHIYNEGMPFASKALDDVSFEIKDRDFVGLIGHTGS
                     GKSTLIQHLNGLLKPSSGEIFINDFNITDKNLNLTEIRKRVGVVFQYPEYQLFEETID
                     KDIAFGPSNLGLEESEIHNRVKASMEAVGLDYEGFKDKSPFELSGGQKRRVAIAGVIA
                     MNPEVLILDEPTAGLDPGGRDEIFNLIKDLHEKKNMTIILSSHSMDDMAKLAKTLIVM
                     NHGSVEFMGTPREVFKSNASKLKDIGLDIPQVLELALKLREKGFDISEDILTLEEAKQ
                     EILKVVRGRGLC"
     gene            18011..18814
                     /locus_tag="PC494_002666"
     CDS             18011..18814
                     /locus_tag="PC494_002666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HDF3913157.1"
                     /translation="MLKDITIGQYYPTSSAIHKLDPRIKLVATIVFMVSIFVVNKFWP
                     YIVVLLCLLAMIKLANIPVKYIVKGVKPLKWIILFTFLINIFFLPGDEIWSFGFLAIT
                     KQGLRQAIFMAIRLIFLVVGTSLLTLTTSPIELTDGIERLLNPFKKIGLPVHELAMMM
                     TIALRFIPTLLDETDKIMKAQMSRGADFESKNLINRAKNLVPLLVPLFVSAFRRADEL
                     AMAMEARCYRGGHNRTKMRESVISRRDYMACVFQVVYLGAIIATRFIAI"
     gene            18846..19577
                     /gene="truA"
                     /locus_tag="PC494_002667"
     CDS             18846..19577
                     /gene="truA"
                     /locus_tag="PC494_002667"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003514691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HDF3913158.1"
                     /translation="MRNIKIKIQYNGKNYCGWQKQPDSLGIQGTIERAIYDITKEETS
                     LIGSGRTDSGVHAIGQIANFKINSGISIESIPMALNAKLPKDISVIEACEVNDDFHSR
                     YSAKGKTYKYLVYNSKFRNPILSEISYQVKYELDFDKMCSEAKSLLGTHDFKGFMSSG
                     SSVKDTVRTIYDIDISKKDDLITFEISGNGFLYNMVRIIVGTLVDMGRGRINEPFLDI
                     IQSKTRSRCGHTAPAQGLFLKKVHY"
     gene            19697..20128
                     /gene="rplM"
                     /locus_tag="PC494_002668"
     CDS             19697..20128
                     /gene="rplM"
                     /locus_tag="PC494_002668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HDF3913159.1"
                     /translation="MKSYIAKPADVQRKWYLVDAEGKTLGRLATEIATVLRGKHKPTF
                     TPHVDGGDFVIVVNAEKIVLSGKKLDQKYYRYHTGYVGGLKEISYRDMMDKKPEEVIS
                     HAVSGMLPKNKLRSRMMTRLRVFAGAEHTHAAQNPEVLNFK"
     gene            20157..20549
                     /gene="rpsI"
                     /locus_tag="PC494_002669"
     CDS             20157..20549
                     /gene="rpsI"
                     /locus_tag="PC494_002669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003515879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HDF3913160.1"
                     /translation="MANVQYYGTGRRKSSVARVRLVAGEGNILVNGRALENYFNYETL
                     IRDVKQPLVLTGNENKYDVIVKVEGGGFTGQAGAIRHGISRALLKADLDLRPALKKEG
                     FLTRDARMKERKKYGLKAARRAPQFSKR"
BASE COUNT         8280 a         2449 c         4319 g         5680 t
ORIGIN      
        1 ctttactaaa ctaatggatt taatataaaa aaagaggggg gtaactcctc tcttttttgt
       61 tttttgttga caagtagcgc taaagcatat atactaaact agtgccttga gacagattaa
      121 caatcaagtt taaggttatg atgttgtaat agaaaataaa attgaaaaaa acagaaaaaa
      181 aacttgaaaa aatgtaacag atgatataaa atataatagt gtgcttgaga gattaagaaa
      241 ataataatta aatcctagtg aaatacgaac tgatatcgat ttaaaagtta caacacaccc
      301 ggagcagtgt atcggtattg gttgtacgca acttgaaaat taaacacgtg ataaaggagg
      361 gaaaacaaaa tggctaagaa tgaaaaaata agaataagat taaaatcata tgatcacaaa
      421 ttattagatt tttcagcagg taaaatagtt gaaactgcta aaaaggctgg atcacaagtt
      481 tcaggacctg tgcctctacc aacagaaaaa caagttgtaa ctatattaag agctgtacat
      541 aagtacaaag actctagaga acaatttgaa ataagaactc ataaaagact aatcgacata
      601 gctaatccaa cacctaagac agttgactca ttaatgagat tagacttacc agcaggtgta
      661 gatatagaaa taaaattata agaaccccta agatattatc ctatagatga ttatcttaga
      721 atgattactc taaaagatgt aatccgctgt aagaattata ggaggtgcta atatgaaagg
      781 aatattaggc aaaaaagttg gtatgactca aatattcact gataaaggtg tagttatacc
      841 tgtaacagct gttgaagcag ggcctatggt cgttactcaa ataaaaacag ttgataaaga
      901 tggatacaat gctatacaaa taggttttga agatgctaaa gaaaaagctt taaacaaacc
      961 taaaaaagga catttagctg ctgctaatgt tttaaagaaa catttaaaag aatttagagt
     1021 agattctgta gaaggataca cagtaggaca agaaataaaa gctgatgtat ttgaagcagg
     1081 tgcaaaaata gatgttactg gaataagtaa aggtaaggga ttccaaggtc caataaaaag
     1141 acatggacaa agtagaggtc ctgaaactca cggttctaga taccacagaa gaccaggttc
     1201 aatgggagct tgttcttacc caggtagagt atttaaaaac aaaaaattag ctggacatat
     1261 gggaagcgta aaggtaacag ttcaaaactt agaggttgtt aaagtagatg ctgacaagaa
     1321 ccttatatta gttaaaggag ctataccagg agctaaaggt tcagtagtaa ctataaaaga
     1381 agctataaag gtttctaaat aatgactaac ctagagaaag gaggaataac aatgccaaaa
     1441 ttaaatgtac taaatgttag tggacaaaac gttggagaaa tagaattatc agattctata
     1501 tttggcgtag aagttaatgg acatgtttta tacgaagttg taaaaaatca attagcaaat
     1561 aagagacaag gaactcaatc tgctaaaact agagcagaag ttagaggtgg cggaagaaaa
     1621 ccttggaaac aaaaaggaac aggtagagca agacaaggtt ctacaagatc tgtacaatgg
     1681 gtaggtggag gagttgcttt tgcacctaaa ccaagaagct acaaatatac attacctaag
     1741 aaggtaagaa gattagctat gaagagtgct ttatcttcaa aagttcaaaa tagtgaagtt
     1801 atagtattag atgcattaaa catggatgct cctaagacta aagaatttgc tcaaatatta
     1861 aacaatataa atgctgctaa aaaagcttta gtagttatag ctgacaaaaa cgataacgta
     1921 ataaaatcag ctagaaatat agaaggtgtt caaactgcat tagttaatac tatgaatgta
     1981 tatgatatat taaaatacga ttcatttata ataactacag atgctgttaa aaaagtggag
     2041 gaggtgtacg cataatgact aatccacatg atgtaataat aagaccagtt gtaactgagc
     2101 acagtatggc tgaaatgggt gaaaaaaaat acacttttgt tgtggctaaa gatgcgaaca
     2161 aaactgaaat aaaaaaagca gtagaaaaag tattcggagt tagtgttgat aaagtaaata
     2221 ctttaaacta cgatggaaaa gttaaaagaa tgggtagaac tcaaggaaga acatcaagct
     2281 ttaagaaagc agtagttaaa ttaactgctg atagtaaaga aatagaattc ttccaaggaa
     2341 tgtagtatta taacaaacga aggagggaaa acagatggct ataaaaaagt ttagaccaac
     2401 ttctcctgcc ttaagacaaa tgacagtttt agtttctgat gaaataacat gtaatcaacc
     2461 agaaaaatct cttttagtta acttaaagaa aaatgctggt agaaacgtac atggtagaat
     2521 aactgttcgt catagaggtg gaggacaaaa aagaaaatat agaataatag attttaaaag
     2581 agataaagat ggtatacctg ctaaggttgc tactatagaa tatgatccaa acagaactgc
     2641 aaatatcgca ttattaaact atgctgatgg agaaaaaaga tatatattag ctccagttgg
     2701 aattaacgtt ggagatacta tattatcagg attaggtgct gatataaaac caggaaactg
     2761 tttagcatta aaagatatgc cagttggtac tatcattcat aatatagaat taaagccagg
     2821 aaaaggagct caattagtta gatctgctgg agtttctgca caattaatgg ctaaagaagg
     2881 aaaaaatgct ttattaagat taccatcagg tgagatgaga ttagtaagca taaactgtaa
     2941 agctactata ggtcaagttg gaaatataga gcatggtaac gtagttatcg gtaaagcagg
     3001 tagaaaaaga catatgggaa taagacctac tgtaagaggt tctgtaatga accctaatga
     3061 ccatccacac ggtggagggg aaggtagatc tccaataggt agaccatctc ctgttactcc
     3121 atggggtaaa ccagctcttg gatacaaaac tagaaagaaa aataaagctt caaataaact
     3181 aatagtatca agaagaacta agtagtaaat ttatttttgc tcggaaagga ggaatataaa
     3241 tgtcaagatc aactaaaaaa gggccttttg tccatgcaag acttttaaag aagatagaag
     3301 ctatgaatgc tagtggaaat aaagaagtta taaaaacttg gtcaagatct tcaactgtat
     3361 ttccacaaat ggtagaaaac actatagctg ttcatgatgg aagaaaacat gttccagtat
     3421 atataacaga agatatggtt ggacataaat taggtgagtt cgttcctact agaactttca
     3481 aaggacataa ggatgacgaa aaatctaata agagaaaata attaaattat gactaagaaa
     3541 ggaggaataa caatggaagc aaaagctact gctaaatacg tacgtgtatc accaagaaaa
     3601 gcaggccaaa tatgtgacct tgttagagga aagaatgttg atgaagcatt agcaatatta
     3661 aagtttactc caagaggagc agcttcaata atagctaagg ttgtaaaatc agctaaagct
     3721 aacgcagaaa acaatcacga aatggatact gaaaaattat atatagcatc aatagttgct
     3781 aatcaaggac caacaatgaa gagattcatg cctagagcta tgggtcgtgc aactacaata
     3841 agaaaaagaa cttctcatat agaggttgtt gttaaagaaa aaaaataatt aatagatagg
     3901 agggaaagta atgggtcaaa aggttaatcc acacggctta agggtcggtg ttataaaaga
     3961 ttgggactca agatggttcg ctactgataa aaaagagttc ggaaacttat tattagaaga
     4021 ccataatata cgtaaattct taaagaaaag attatactca gctggagttg ctaagataga
     4081 aatagaaaga tcagctaaca aaataaaaat ggacttacac gttgctaagc ctggtgtagt
     4141 tataggaaga gctggtgcag gaatcgaagc attaaaagct gaattagaaa aaatgacaaa
     4201 gaaaactata atagttaata tagtagaagt aagaagtaca gataaaaatg ctcaattagt
     4261 agctgaaaat atagctttag ctatagagag aagggttgct ttcagaagag caatgaaaca
     4321 agctatacaa agagcaatga aatctggtgc taaagggata aaagtttctg cttcaggaag
     4381 attaggtgga gctgaaatgg ctagaactga aggttatagt gaaggaaatg tgccactaca
     4441 aactttaaga gcagatatag attatggttt cgctgaagct gatacaactt atggaaaaat
     4501 cggtataaaa gtttggatat gtaatggtga agttttacca actagagacg gtgtaaatcc
     4561 aagagaagaa agcagaaaga gcgatagaag agacaacaag agagataata gaagaaacga
     4621 tagaagagga aatgacagaa gaggaaatga taacagagga aactacagag gacaaagacc
     4681 tcaaggtgga tcaagacctc aaagaactga aaacaaagga aattaataat agttaggttc
     4741 aaggaaggag gaaaaatact catgttaatg ccaaaaagag taaagcgtcg tagagttcat
     4801 agaggaagca tggctgggca agctcataag ggtaataaag ttacttatgg tgagtttgga
     4861 ttagtagcat tagaagcttc ttggataact tctaatcaaa tagaagctgc cagaattgcg
     4921 atgactagat atataaaaag agggggaaag gtttggataa aaatattccc tcataaacca
     4981 gtaacaagaa aaccagcaga gactcgtatg ggtgcaggga aaggttctcc agaatattgg
     5041 gtagctgtag ttaagccagg aagagttatg tttgaattag caggtgtttc tgaagataaa
     5101 gcaagagaag ctatgagact tgctgcacat aaattaccaa tcaaatgtaa atttgttaaa
     5161 aaagaagatt tagaagtaaa gggtggtgaa taggatgaaa gctaaagaat taagagattt
     5221 aacaagcgaa gagctaatga acaaattaaa cgacttcaaa agtgaattat ttagcttaag
     5281 attccaatta gctactggtc aattagaaaa tacagctaga ataaagtttg ttaagaagga
     5341 tatagcaaaa gttaaaactg ttcttgctga aagaaagtta tacgaaacta gagcttaatt
     5401 tggaaaggag gctttttaaa catggaaaga ggaagaagaa aagttagaat aggccgtgtt
     5461 gttagtgata agatggataa aacaatagta gtagctgttg aagaattcgt acgtcatcca
     5521 ctatataata aacgtgttaa gagaactaag aaattcaagg ctcatgatga aaagaatata
     5581 tgtaacatcg gagatagagt taaaataatg gaaactagac cattatctaa agataagaga
     5641 ttcagactag ttgaagttgt tgagaaagtt aagtagtttt tgaagaagga gggattacga
     5701 tatgatacaa caagaatcac gtctaagagt tgctgataac tcaggagcta aagaactttt
     5761 atgtatacgt gttctaggcg gaagtaaaag aagatatggt aacataggcg acgttatagt
     5821 tgctactgtt aaaagtgcaa cacctggtgg agttgtaaaa aaaggtaagg ttgttaaagc
     5881 tgttatagta agaagcaaac aaggcgtaag acgtaatgac ggaagctata tatcttttga
     5941 tgaaaatgct gctgttataa taaaggacga taaaactcca gtaggaactc gtatattcgg
     6001 gcctgttgct agagagttaa gagacaatga attcatgaaa atagtttctc ttgctccaga
     6061 agtactataa ttaaggaggt gcaataggac atgatgcgtg ttaaaaaagg tgacactgtt
     6121 gtagttatag caggtaaaga taaaggtaaa aaaggttcag ttttaaaggt atatcctaaa
     6181 actagcaaag tgttagttga aggtgtaaat gtaataacta aacatcaaaa accaagtgct
     6241 atgaaccaac aaggtggaat aataaataaa gaagccccaa tacacatatc taatgtaatg
     6301 ccatttgatc ctgaaacagg aaaaggcgtt agagtaagat atgaagtaaa agatgggaac
     6361 aaagtaagag tatcagcaaa gagcggaaaa gaattataat aaatattgct tgaaaggagg
     6421 gaccttaaat ggcttctaga ttacaagaaa aatacatgaa agaagttgct cctgctttaa
     6481 tggagaaatt tggatacaaa aacgtaatgg agatacctaa gttaaataaa atagttatta
     6541 acatgggtat aggtgacgct agagaaaatc caaaaggatt agaaaaaggc gttgaagaat
     6601 tagaaatgat atcaggacaa aagcctgtta taactaaagc tagaaaatct gttgctaact
     6661 tcaaattaag agaaggaatg ccaataggaa caaaagttac attaagagct gacaaaatgt
     6721 tctactttat ggacaaatta gtttcagttt ctttaccaag agttagagac tttagaggag
     6781 ttaaccctaa tgcttttgat ggtagaggaa attatgcttt aggagttaaa gaacaattaa
     6841 tattccctga aatagaatat gataaaatag ataaagtaag aggaatggat ataatatttg
     6901 ttactacagc aaaaactgac gaagaagctc gtgaattatt aaaattatta ggaatgccat
     6961 tttctaagta agcaaaggag ggattcccgt ggctagaaaa gcgatggttg ttaagcaaca
     7021 aagaaagcaa aagtacgcta ctagagaata cactagatgt actatatgcg gaagaccgca
     7081 ttcagttttg aaaaaatttg gtatatgccg tatatgcttt agagaattag cttataaagg
     7141 tcaaatacct ggtgttagaa aagcaagctg gtagaagctt gattagaatg gaaggagggc
     7201 aacaaaatga caatgacaga tccaattgca gatatgctta ctcgtataag aaatgctaat
     7261 gttgttaagc atgaaactgt agatgttcca gcttctaata tgaagaaaga attagctaga
     7321 atcttattag aagaaggttt cataagaggt tatgatgtta tagaagatgg aaaacaaggt
     7381 atcataagaa tacaattaaa gtacggacaa gaaggcgaaa gagttataac aggtcttaag
     7441 aaaatatcta agcctggaat gagagtttac gctgctaacc atgagatacc aaaagtatta
     7501 aacggattag gaatatcagt tatatctact tcaaaaggaa tattaactga caagcaagct
     7561 agaaaagaaa atgttggtgg agaagtaatc tgctacgttt ggtaattaat atgaacaatg
     7621 taaggaggtg cgaccatgtc aagaataggt gttaagccaa taataatacc agcaggtgtt
     7681 gaagttacta tagctgaagg aaatttagtt acagtaaaag gtccaaaagg aactttaact
     7741 aaacaattaa gtgctgagtt aaacataaaa aaagaagaaa atacaataat ggttgaaaga
     7801 ccaactgata ataaaaaaca tagatcttta cacggactaa ctagaacttt attagataat
     7861 atggttgtag gtgtaaatac tggtttcgaa aagaaattag aattaaaagg tgttggatat
     7921 agagctcaaa aacaaggaaa gaaattagtt atgaacttag gtttctctca tccagttgag
     7981 atggaagatc cagaaggaat aactgttgaa gctccaaacc aaacagagtt aatagtaaaa
     8041 ggtatagaca agcaattagt agggaattat gctgctaaga taagagcttg gagaaagcca
     8101 gagccataca aaggtaaagg tataaaatac gttgatgaag taatcagacg taaagaagga
     8161 aaaactggta aaaaataata ccaaaactta aacgctagaa aggagtgagc taggtgttaa
     8221 aaaaggctga taaaaatgct aatagacttc aaagacataa gagagttcgt agaaaaataa
     8281 gcggtacttc tcaaagacca agattatgtg tatttagaag tgctaacaat atatatgctc
     8341 aaataataga tgacacaaaa agagtaactc tagttgctgc atcttcttta gaagcagaag
     8401 ttaagagtgc tgtcaatcat acaggaaaca aggaagcagc taagaaagtt ggagaattag
     8461 ttgctaaaaa agctgttgaa aaaggaatca ctgaagttgt atttgacaga ggtggatact
     8521 tatatcatgg aagaattcaa gaattagctg aaggtgctag agaagctggt cttaagttct
     8581 aatacgaagg agggaaaaat acatgctacg tcgtaagccg atagatgcag gacaacttga
     8641 cttacaagaa aaagttgttg aagtaagacg tgttactaag gttgtaaaag gtggtagaaa
     8701 tttcagattt gcagcattag tagttgttgg agatgaaaac ggacacgttg gtataggtgc
     8761 tgggaaagca atggaagtac cagacgctat aaaaaaagca gttgaagatg ctaagaaaaa
     8821 tctaatagta gtgccaatag ttgggactac aattcctcac gaagtacgcg gacactttgg
     8881 tgctggaaat atattaataa tgcctgctgt agaaggtaca ggagtaatag ctgggggacc
     8941 tgctagagcc gtacttgagc tagctggact aaaagacgtt agagctaaat ctttagggtc
     9001 taacaatcca agaaatatgg taaatgctac aatagaagga cttaattctc taaaaacagt
     9061 tgaagatata gctaaactta gaggtaaaaa agttgaagaa cttctagggt aaggaggtag
     9121 tgtaaaatgg ctaaattaca aataaagtta gttagaagtg ttataggaac tactcctaac
     9181 caaaaaaaga atgttgaagc gttaggatta agaaaaagag aacaagttgt tgtaaaagaa
     9241 gacaatgctc aaacaagagg tatgataaat aaagtaagtc acttattaga agtaactgaa
     9301 atagctgaat aatttttata aagtagtgca aggaggtgca atccatgaag ttacatgagt
     9361 taaaacctgc tgaaggtgca gtaagagcta agagaagatt aggtagaggt actgcaactg
     9421 gacaaggtaa aactgcagga cgtggacaaa aaggtcaatg gtctcgttct ggtggtggag
     9481 taagagtagg atttgaaggt ggacaaatgc cactagctag aagacttcct aagagaggtt
     9541 tcaataacat atttaagaaa gtttacacag aagttaatgt tgaagtttta aacagatttg
     9601 aaaatggaac agaaataact gcagaattat taaaatctac taaaactata agcaaaatag
     9661 gtaaagacgg aattaaaatc ttaggtgaag gtaatttaga gaaagcttta actgttaaag
     9721 ctgctaaatt tacagcttca gctcaagaaa aaatagaaaa agctggtgga aaagcagagt
     9781 tagtataata acctgctaat ctcctagcca gtacaggcgg ggtgaattag cgtgctgtca
     9841 aaattaaaac aagcttggaa gattaaagca gtaagaaaaa aagtaatgta tacacttatg
     9901 atgatcgtga tattcagaat aggtactact ataccagttc caggcataga cactagtatt
     9961 atacaaaaga tggtaggcgg caatagtcta ctttctctgt ataatatgtt tactggtgga
    10021 gcatttagta acttttcact atttgcttta ggtataagtc catatatcac tgcatcaatc
    10081 ataatacaac ttctaacagt aggttttgaa agtttagcag aacttcaaaa atctggtgaa
    10141 gaaggaaaga aaaaaatcaa taagtacact aaatatacag cactagctct agcagttgta
    10201 caagctttgg gaattacatt aggaattgta agaagtgctt taatatcaaa tagtgtgttt
    10261 tttatcacaa ctgttgtaat aacattagtt tcagcaagta tgttagtaat gtggattggg
    10321 gacaaaatta ctgaaaaagg aatcggtaat ggtagttcag taataatatt tgcaggtata
    10381 atatcaagaa tacctacaga tgttattaaa atatcgcaac aagttaaatc tggcgaagtt
    10441 gcaccttggg ttatagtgat tctagctgta gttatattac ttacagtaac aggagttaca
    10501 tttatacaag aagcaactag aaagatacct gtacaatatg ctaaaagagt tgttggaaga
    10561 aaaatgtatg gaggacaaag ttctcatata ccaatgaaag ttaaccagtc aggagttatg
    10621 cctataattt ttgctagttc acttttagct ttccctcaaa caatagctat gtttatgggt
    10681 ccaaatgctc aggcttttgt tcaaaaatac ttaagtatgg caacagaaca aggattttgg
    10741 acatatagat caattgagat tctacttata attttcttct catattttta tacaactgta
    10801 tcatttaata cagaagacat atctaaaaat atgaaaaata atggtggatt tataccaggt
    10861 ataagaccag gtgagcctac tatggattat ttaaatagaa ttttaactag attaacttta
    10921 gctggagcta ctttcttagc aataattgct atggtgccag ctcttacaac acattatatg
    10981 aaagtaaata tgagtctagc tgggacttca ttgctaatcg ttgttggagt tgctttggag
    11041 cttaagagac agttagagtc aaacttagtt atgagaagct atcaaggttt cttaaaataa
    11101 aatggagatg gataatatga gaataatatt acttggacct ccaggtgctg gtaaaggtac
    11161 tcaggcggca ggaatagtag aaaaatacaa tatacctcat atatcaacag gagatatatt
    11221 cagaaagaat ataaaagagg gaacagaact tggaaaaaaa gctaaagaat acatggacca
    11281 aggtttatta gtaccagatg agttaactgt aggtttagtt actgatagaa tatctcaaga
    11341 agattgtaaa aatggattta tgttagatgg atttccaaga aatgtagcac aaggagaaca
    11401 tttagatatc ttcttaaaaa atgctggtat atcactagat aaagttgtca atattgaagt
    11461 tgataagagt atattagtgt ctagagcagt tggtagaaga atatgtaagt cttgtggagc
    11521 tacttaccat gttgagttta atcctcctaa agtagaaggt gtatgtgatg tatgccaagg
    11581 agaattatat caaagagctg atgataatga agaaactgta tctaagagaa tacaagttta
    11641 tctagatgaa actaagcctt tagtagatta ttatagcaaa caaggtataa tagcagatat
    11701 aaaaggtgat caagcaatag ataaagtatt tgaagatatt gtcgcagcct taggaagtgg
    11761 aaaataaatg attatcttga aatcaaaaaa agaaatagaa cttttaagag aagcaggtaa
    11821 aatagttgct gacactcatg aagttttaag aaaagctatt tctccgggaa tatctacttt
    11881 agaattagat aaaatagctg aagagaatat aagaaaatac aatgcagaac cttcttttaa
    11941 aggatatgga ggttttccag gaagtatatg tgcttctatc aatagagagg tagtacatgg
    12001 tattccagga gaaactatat tacaagaagg tgacattgta agtttggata taggagccta
    12061 ttataaagga tatcatggtg attctgcgaa aactcacgga gtaggcatga tatctgaaga
    12121 agataggaaa ttgatagaag taactagaga aagcttctat gaaggaataa aatttgctaa
    12181 attaggatat agactttcag atatctcaca cgcagtacaa acacacgttg agaaacatgg
    12241 tttctcggta gttagagatt tagtgggtca tggagttgga gcaaatcttc atgaagaccc
    12301 acaagtacct aattatggac tcccaggaaa aggaccaaga cttagagaag gaatggttat
    12361 tgctatagag ccaatggtta atgcaggtcg ttatcatgta aagactctat cagatgggtg
    12421 gacgactgtt acaatagatg gaaaaaaatc agctcattat gagcatacga tagcaattac
    12481 tgaacatgaa cctttgatat tgacaaagtt gtaatttaaa aagtaggtga aaaaagtgct
    12541 atcagataat ttaagtatag gtcaagttgt taaagtttca ttaggacgag ataaaggaaa
    12601 tttattcttt gtagtcaaaa taattaataa tgaatatgta ttaatagctg atggaaaaaa
    12661 gagaaaactt gacaaaccta agttaaagaa agtgaagcac ttaaaaaaat ataattttat
    12721 taatgatgaa gttagaaaaa gagtagtatc tggacaagag attacagatt cttttttaag
    12781 agctgaactt actaagttaa attagataat ttaacttatt gaaatggagg gctggttagt
    12841 taatggccaa aaaagatgtt atagaattag aaggtacagt ttcagaagct ttacctaatg
    12901 ctatgttcaa agttaaacta gaaaatggac atgagatatt atgccacatt tctggaaagc
    12961 taagaatgaa cttcataaga attcttgaag gtgacaaggt gaatgttgaa ctttctccat
    13021 atgaccttac aagaggaaga attacttggc gtaagaagta gactatatta atatttagtc
    13081 taaggaggga ttaataatga aggttagacc atcagtaaaa ccaatatgtg aaaaatgtaa
    13141 agtaataaaa agaaaaggaa aagtaatggt tatctgtgaa aatccaaagc ataagcaaaa
    13201 gcaaggataa gaaattatta ctagcatttt gttaaatttt atagtataat actatattgt
    13261 gatgttaaca aaagaacgtt aaaatcgttg aacaatctgg cgtaggattg gcatatgatg
    13321 tgaagtttta aacactaaaa actatgtgta ggaggtgcga tcatggcaag aatagctggg
    13381 gtagatttac ctagagaaaa aagagcggag ataggcttaa cttatatata tggtataggt
    13441 aaagcaactg ctaacgaaat attagctaag gctgagataa atccagatac tagaataaaa
    13501 gatttatcag aagatcaagt taatgagtta agaaaagtta tagatgacga tttcttagtt
    13561 gaaggtgact taagaagaga aattgcttta aacataaaga gattaagaga tataaaatgt
    13621 tatagaggaa taagacacgc taaaggtctt ccattaagag gacaaagaac taagactaat
    13681 gctagaacta gaaaaggtcc tagaaaaaca gtatctcgta aaaagaaaaa ataaataaat
    13741 aataactaga tgaaggaggg aaaaggaaaa tggctaaacc aaaaaagaaa gttacacgta
    13801 ttagaagaag agaacgtaaa aatatagaac gtggtcatgc tcatatacaa tcaactttca
    13861 ataatacaat aataacttta actgacgttc acggaaatgc tatatcttgg gcaagttctg
    13921 gacaattagg attcaaagga tcaagaaaat caactccatt tgcatctcaa atggctgctg
    13981 aaacagctgc aaaagctgcg atggaacacg gactaaaaag tgttgaggta ttcgtaaagg
    14041 ggccaggttc aggaagagaa gctgcaataa gagctttaca agcaactgga ctagaagtaa
    14101 ctatgataaa agacgttact ccaatcccac ataacggatg cagaccacca aagagaagaa
    14161 gagtgtaatt aataagagta caataggagg tgtagataaa tggcaagata tacaggtgca
    14221 tcatgtagac aatgccgtag agagggaatg aaattattcc ttaaaggtga tagatgttat
    14281 acagacaaat gtgctatagt aaaaagaaac tatgctccag gtcaacatgg ccaaggaaga
    14341 aagaaagttt ctaactatgg attacaatta agagaaaaac aaaaagttaa aagaatatat
    14401 ggagttttag agactcaatt tagaaattta tatgaacgtg ctgaaaatat gcctggtaaa
    14461 gcaggtgaga acttattaag tttattagag agaagattag ataatgtagt ttacagaatg
    14521 ggactagcat cttctagaaa agaagctaga caattagtga ctcatggtca tttcacttta
    14581 aatggaaata aagtagacat accttcatta atagttaaag ttggagatgt tatagaagtt
    14641 aaagagaaat caagatcttc tgcaaaattc aaaaatttag tagaagttaa ctcaagaata
    14701 gctcctaagt ggttagaagc taatgtagaa ggaatgacag caaaagtagt tggtgttcca
    14761 acaagagaag atatagatct tgagatagca gagcacttaa tcatagaact ttactctaaa
    14821 taataagcac acttttaaaa attattttaa aattttgttt accctcagtg gattactgaa
    14881 ttttaaggag ggttttgtcc atgatagaaa tagaaaagcc aaaagtagat atagttgagc
    14941 ttagtgaaga ctatagatat ggtaagtttg ttatagaacc tctagaaaga ggatatggaa
    15001 taactatagg taacgcatta agaagaatat tattatcatc attaccaggt gtagcagtga
    15061 atgctataaa aatagatgga gttcttcatg aattttcaac aatacctggt gttaaagaag
    15121 atgttactga gataatatta actttaaaag agctttcagc aactatagat ggtgaaggaa
    15181 gtagaacact taaaatagaa gctcaaggac catgctctat cacaggtgca gatataatct
    15241 gtcctccaga tgttgaaata ttaagtaaag atttagcaat agctacatta gatgataatg
    15301 ctaaacttaa tatggagata tttgtagata aaggtagagg ttatgtttct gctgaagaaa
    15361 ataaaacaga gaatgttcca ataggtgttt tacctgtgga ttcaatatat actcctgttg
    15421 agaaggttag ttatcatgtg gaaaacacaa gagttggtca aaaaacagat tatgataaat
    15481 tagtactaga agtttggact aatggtagta taaatcctca agagggaata tcattagctg
    15541 caaaggtatt agttgagcat ttaaacttat ttatagactt aactgaacat gtaagtagtg
    15601 ttgaaatcat ggtagaaaaa gaagaagatc aaaaagaaaa agttcttgaa atgactatag
    15661 aagaattaga tttatcagtt agatcatata actgtttaaa gagagcggga attaatacag
    15721 ttgaagaatt agctaataaa tctgaggatg atatgatgaa ggttagaaac ctaggtaaga
    15781 agtcattaga agaggtaata caaaaactag aagaacttgg attgggatta aaaccaagtg
    15841 aagaatagcg agcaaaggag ggataagaat ggctaagtac cgtaaattag gacgtgaaac
    15901 agctcacaga aaccttatgt taagaaactt agtaacttgc ttactaagaa gtggaagaat
    15961 agaaactaca gtgactagag cgaaagaaac tcgtagaatg gctgaaaaga tgataactct
    16021 tgctaagaga ggagatcttc atgctagaag acaagtttta gcttatgtta tggatgaaac
    16081 agtagttaat aacttattca cagatttagc tccaaaatat gctgagagaa atggtggata
    16141 cactagaata ataaaaatag ggccaagaaa aggcgatgct gctgaaatgg cttttataga
    16201 attagtatag taaggaaagg attaggcttg atggcttaat ctttttttta tttttttgac
    16261 taaggtatga tataataatg tgtaaaatga tttttataag ttattgctta ctaaaaggag
    16321 tatgagttaa tggataatat agtaaaggta aataatattt cgtttgagta tattacagat
    16381 gaagcaaaac ttaaagcaat agataattta agcctagatg ttaaaaaagg agaatttgtt
    16441 gcgataatag gacataatgg ttctggtaag tctactttat ctaaaaactt aaatgctatt
    16501 cttatgccca ctgaaggaaa tattcttatt gatgatatgg atactaaaga agaagaaaga
    16561 ttatgggata taagacaaac tgcaggcatg gtatttcaaa atccagataa tcaaatagtt
    16621 gctactatag tagaagaaga cgttgcattt ggacctgaga acttaggtat agaaccaaaa
    16681 gaaataagac gaattgtaga ggagtcttta aaaagtgtag gtatgtatga tttaagagat
    16741 agacagcctc atttgttatc aggaggtcaa aagcaaagag ttgcaatagc aggaattatt
    16801 gctatgaggc ctaaatgtat aatctttgat gaagcaacag caatgttaga tccatctgga
    16861 agaaaagaag ttatgaaaac aataaaaaga cttaataagg aagaaaatat aactgttata
    16921 catataacgc actttatgga agaagcagta gaagctgata gagttgtagt tatggaaaaa
    16981 ggaaagaaaa tcttagaggg aactcctaga gaagtattca gtaaaataaa gatgttaaag
    17041 gaaatcggtt tagatgtacc ttgtatgaca gagttatcta gtttattaat agaagaaggt
    17101 ataaatatta gtagtgatat attaactgtg gatgagatgg tgatggaatt atgtcaatta
    17161 tagtaaagaa tttaacacat atatataatg aagggatgcc ttttgcaagt aaggcacttg
    17221 atgatgtttc ttttgagatt aaagatagag attttgttgg tcttataggt catacaggct
    17281 caggaaaatc tacattaata caacatttaa atggattact aaagccttcc tcaggagaaa
    17341 tatttataaa tgattttaat ataacagata aaaacttgaa tttaactgag attagaaaaa
    17401 gagtaggggt tgtatttcaa tatccagaat accaattgtt tgaagaaacg attgataaag
    17461 acatagcttt tggaccctct aatttaggct tagaggagtc tgagatacat aacagggtaa
    17521 aagcatcaat ggaagctgta ggacttgatt atgagggatt taaagacaaa tctccttttg
    17581 aattatctgg gggacaaaag cgtagagtag caattgctgg agttatagcc atgaacccag
    17641 aagttctcat attggatgaa ccaactgctg gtcttgaccc tggtggaaga gatgaaattt
    17701 ttaacttaat aaaagactta catgaaaaaa agaatatgac tataatacta tcatcacata
    17761 gtatggatga tatggcaaag ttagcaaaaa ctttaattgt tatgaatcat ggtagcgtag
    17821 aatttatggg aactcctaga gaagtattta aatcaaatgc tagtaaatta aaagatatag
    17881 gattagatat tccacaagtt ttagagcttg cattgaaatt gagagaaaaa ggctttgaca
    17941 tcagtgagga tatattgact ttagaagaag caaaacagga aatattaaaa gttgtgagag
    18001 gacgaggatt atgttaaaag atataactat agggcaatac tacccaacaa gttctgctat
    18061 tcataaatta gatccaagga taaagcttgt agcgacaatt gtatttatgg tatctatatt
    18121 tgtagtaaat aaattttggc cttatatagt agttttatta tgtttattag ctatgataaa
    18181 attggctaat ataccagtca aatatattgt taagggtgtt aaacctctta aatggattat
    18241 tttgtttaca tttcttataa atattttttt cttaccaggt gatgaaatat ggtcatttgg
    18301 atttttagct attacaaaac agggtctaag acaagcaatt tttatggcaa taagattaat
    18361 atttttagta gttggtacat cattgcttac tttaacaact tcaccaatag aattaactga
    18421 tggaatagag agattgttga atccatttaa gaaaattggt ttgccagttc atgaacttgc
    18481 aatgatgatg acaattgctt tacgttttat tcctacattg ttagatgaga cagacaaaat
    18541 aatgaaggct cagatgtcta gaggtgcaga ttttgaaagt aagaatctta taaatagagc
    18601 aaagaattta gtaccacttt tggtaccttt atttgtaagt gcatttagaa gagctgatga
    18661 attggctatg gccatggagg ccagatgtta cagaggtgga cataatagga ctaagatgag
    18721 agagtctgtt atatcaagaa gggattatat ggcatgtgta tttcaggttg tttatctggg
    18781 agcaattata gctactagat ttatagcaat ttaattaata agttatagat ataatgaggt
    18841 aaagtatgag aaatataaaa attaaaatcc aatacaatgg taagaattat tgtggatggc
    18901 aaaagcaacc tgattcttta gggatacaag gtacaattga aagggctata tatgatataa
    18961 caaaagaaga aaccagtctt atagggtctg gtagaactga ttcaggagtt catgctattg
    19021 gtcagattgc aaattttaaa attaattcag gtataagtat agaaagtata ccaatggcac
    19081 taaatgccaa gttgccaaaa gacatatcag ttatagaagc atgtgaagta aatgatgatt
    19141 ttcactccag atacagtgca aaaggtaaaa catataaata tttagtatat aatagcaagt
    19201 ttagaaatcc aatacttagt gagatatcat atcaagtaaa atatgaactt gattttgata
    19261 aaatgtgttc agaagcaaaa agtttattag gaacacatga ttttaaaggt tttatgagtt
    19321 ctggttcatc tgtaaaagat acagttagaa cgatatatga tattgatata agtaaaaaag
    19381 atgacttgat tacttttgag attagtggta atggtttttt atataacatg gtgaggatta
    19441 ttgttggaac acttgttgat atgggtcgtg gcagaattaa cgaaccattt ttagatataa
    19501 tacaatcaaa aactaggtca agatgtggac atacagctcc agcacaagga ttatttctca
    19561 aaaaagttca ttattaactt gacacaccag gctacatgta ttaaaatata tgagaatgtg
    19621 ttaataagtc cacttgcccc ggacttgaca taaacggtaa aaaaatttta tgaaaagtag
    19681 ttaaggaggg acagttatga aaagttatat agctaagcca gctgatgtac aaagaaaatg
    19741 gtacttagtt gatgctgaag gaaaaacatt aggtcgttta gcaacagaaa ttgcgacagt
    19801 attgagaggt aaacataaac caacatttac tcctcacgtt gatggtggag attttgttat
    19861 tgtagtaaat gcagaaaaaa tagttttaag tggtaagaaa ttagatcaaa aatattacag
    19921 ataccatact ggttatgtag gtggattaaa agaaatatct tacagagata tgatggataa
    19981 gaaaccagaa gaagttatat cacatgctgt aagcggtatg ttacctaaaa ataaattaag
    20041 aagcagaatg atgactagat taagagtatt tgcaggtgct gagcacactc atgcagctca
    20101 aaatccagaa gttttaaact ttaaataaga ttaataggtg aaaggaggag tttataatgg
    20161 ctaacgttca atattatgga actggaagaa gaaaaagttc tgttgctaga gtaagactag
    20221 ttgcaggtga aggaaatata ttagtaaatg gaagagcatt agaaaattat tttaattatg
    20281 agacattaat aagagatgtt aaacaaccat tagttttaac tggtaatgaa aataaatatg
    20341 atgttatagt aaaagttgaa ggtggaggat tcactggaca agctggagct ataagacatg
    20401 gaatatctag agctttatta aaagctgatt tagatttaag acctgcttta aagaaagaag
    20461 gtttcttaac tagagatgca agaatgaagg aaagaaagaa atacggatta aaagcagcaa
    20521 gaagagctcc acaattctca aaaagataat tacttatttt tttggaaaag caaaatcctt
    20581 tatttactgt tattcagaaa gtattggtat tttaaaaatg ttgggttaag ttaattattg
    20641 atatataata aaataataag atatcttatt aggatgtttt tcattaagaa gaacatcctt
    20701 tttattttga ctatttaata aaaaacat
//
LOCUS       DAMKNB010000066        20485 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.068, whole genome shotgun sequence.
ACCESSION   DAMKNB010000066 DAMKNB010000000
VERSION     DAMKNB010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 20485)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20485)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20485
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.068"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            complement(83..367)
                     /locus_tag="PC494_002670"
     CDS             complement(83..367)
                     /locus_tag="PC494_002670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3913161.1"
                     /translation="MLVYNKSFYPNDIFPRLDFSKIKKQLKLIDNDLSDFGSICIIEK
                     EHYTISVNSIGEINVYYDLEYENKVYRIVYEIEKLFKSQVGRFSISTYRN"
     repeat_region   478..1745
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=602..630
                     /rpt_unit_seq="atttacattccatatagttaatataaaac"
     gene            complement(2576..3448)
                     /locus_tag="PC494_002671"
     CDS             complement(2576..3448)
                     /locus_tag="PC494_002671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HDF3913162.1"
                     /translation="MEETNEMKDSKHLISNIQSQYTRLSKGQKLIAQYILNNYDKVAF
                     MTACKLGETVGVSESTVVRFANALGYSGYPKLQAALQELIKNKLTTVQRVEMAHDYSD
                     DFAILNKVLKSDIDNIRSTLEEIDERAFKEASNKLLRARKIYILGMRSSFVVAQYLGF
                     YLDIILDNVHIIRMDMGDAFEQIVRINEEDVIVAISFPRYSKKSYQIVNYAKEKGAHV
                     ISLTDSLFAPVASLADNTLLVKSNMASFVDSLVPALSISNALAISVGMKEKEDIKQHF
                     DDLEQIWKRYSVYE"
     gene            complement(3842..4420)
                     /locus_tag="PC494_002672"
     CDS             complement(3842..4420)
                     /locus_tag="PC494_002672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HDF3913163.1"
                     /translation="MAYAKYLTKITDINKFYLENIINEGDIVIDATMGNGYDTRYLAE
                     KVGEKGFVYAFDIQEEAIKSTRKKLEKEGYTDRVKLIFDGHEKMNQYIKEEVSCVLFN
                     LGYLPRAKHSIITKPDTTLKAIKLSLEMLKENGVISIAIYTGHDGGQEEKDCIYNLVN
                     NLNQDEFNVLESKFLNQVNNPPQLILIEKKKA"
     gene            complement(4478..5194)
                     /locus_tag="PC494_002673"
     CDS             complement(4478..5194)
                     /locus_tag="PC494_002673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HDF3913164.1"
                     /translation="MRINKYIASCGIASRRKAEEIILGGRIKVNGSVVKELSFNIDEE
                     KDIVEFDNKKVKPSENYIYIVLNKPEGYITTVKDQFNRPSVIDILKDVRERVYPIGRL
                     DYETSGLLILTNDGDLTYKLTHPKHEIDKTYVASVKGIISDDEIRQFETGLKIEDYTT
                     APAKIRVTKENKEKNYSVCEITIHEGRNRQVRKMCKAINHPVLNLRRISVGKIVLKDT
                     KVGEYRYLTEDEIKYLKSIK"
     gene            5385..6470
                     /locus_tag="PC494_002674"
     CDS             5385..6470
                     /locus_tag="PC494_002674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HDF3913165.1"
                     /translation="MIIISKENIKYYLIVVFIGILFFKFINTPSDFISSIEGFLKFFS
                     PFLLAILLALLLNPLVMLFEVKFKAHRLLAIFLSYIFIGFILAFAIRLLIPSIANTLN
                     RLINEMPMYTDYIDSFIEKNMSNIDFLKTLIPHIQHSLDNLLKEASNFVGKIPKNFLI
                     YTLSISSMLFNMTMGFILSIYIIYDKEKIALGFKRFLYSSTARNKADNIIEFFRTTHD
                     IFYDYLLGRILDSLIIGIIAFLGFQFVIRIENALFLASIIFLGNIIPYFGPFIGAIPP
                     IAMTILYSPQKTIWVIAFLFILQQLDGNFIEPKVMGNQVGIGAIWVISAILVGQSLFG
                     FIGVFLSVPIAAVVKTYVDKYIDNRLQ"
     gene            complement(6625..7284)
                     /locus_tag="PC494_002675"
     CDS             complement(6625..7284)
                     /locus_tag="PC494_002675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HDF3913166.1"
                     /translation="MRGRVILLISILSIFLVGCSFNKKDEINLVEQGKTYLEKHNYKK
                     AMESLSSALEEDSTNENARAMYMQAMRMSNMTEFEELKNYEGAIKELKLIEKIKNGSS
                     VIKEEATKKKEELTKLEKEQNEAEEQRKKKAKDTAGEDRYRVESDARKSSYSGSSKNN
                     KSSSKNNDKKSDSNKSDNNNSSSQNQEKPNNSNPTPAPTPQDTTGGSDSGGNSQNSNN
                     Q"
     gene            complement(7501..8793)
                     /gene="lysA"
                     /locus_tag="PC494_002676"
     CDS             complement(7501..8793)
                     /gene="lysA"
                     /locus_tag="PC494_002676"
                     /EC_number="4.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HDF3913167.1"
                     /translation="MKLHGTMTVNNDELYIGGVSCLELSKKYQTPLYVFDEALVRQNC
                     REYVEYFKAREGKNKVAYAGKAFLPLYMCNLINEEQMCLDVVSGGELYTAYKSNFPME
                     KVFFHGNNKTKEEINMGLDLGVGKFVVDNFYELDLLEALCEDKGKTQEIYFRITPGIE
                     AHTHDYIKTGQIDSKFGFALVNGDLFRAIEKLSEYKNIKLVGLHAHIGSQIFDVEPYI
                     DTVDIMMNLVKEIKEKFNIQLTEIDLGGGVGVYYSEGDKPKTIKEFCETIITKAETSC
                     KELGIEVPTLVIEPGRSIVANAGSTLYTVGSIKDIKDVRVYVSVDGGMTDNVRPSLYQ
                     ASYECSIVNKINHEAMNHVTIAGKCCESGDILIGDINIMDIKSGDILITTSTGAYGYS
                     MSSNYNKIPRAAVVSVFDGNDKIICKRQSYEDLLALEI"
     gene            complement(8811..10004)
                     /locus_tag="PC494_002677"
     CDS             complement(8811..10004)
                     /locus_tag="PC494_002677"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HDF3913168.1"
                     /translation="MSIIVQKYGGSSVADTEKIKSIAENIIERRKENPQMVIVVSAMG
                     KSTDEYITLAKELSNEPSKRELDALMSTGEMISASLLSIALNALGCKAISYNAYQLNI
                     KTSGLHGKSQIDDINVNRIKNSLDEGNVVIVTGFQGINEDGDVTTLGRGGSDTSAVAL
                     AVKLNGKCEIYTDVDGIYFTDPRKYSKASKLDEIEYEEMLELASLGAQVMHSRSIELA
                     QKYGVEIYVGRTCGTEKGTYIRGGKDMKLEDKVITGLATSDDDSSITIKDFKAENISS
                     LFEDIATIGISVDMISQTAPILDKISVSFTVPKEELGECKKIVSKYTDEEHVVIDNNI
                     TKFSLVGLGMKNTSGVAAKVFKIFNENGIMIKLITTSEIRITCAINSDDKQVAIEKIA
                     EVFNI"
     gene            complement(10365..10982)
                     /locus_tag="PC494_002678"
     CDS             complement(10365..10982)
                     /locus_tag="PC494_002678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3913169.1"
                     /translation="MTNMEKEILLLISRVRCVTESQFRKIYGDQKRYNKKNFKKTLRK
                     MCSEYTLKKYPCDVDYYNYKDLSYVYYLNGSKLFKGDDLIKALVGSELVVRINTAGCD
                     VKRFYRNVSVDDVKYDLFIEYTDQFGNIKQVLVDVDLNNEIDISKYENLSKKIDKSTI
                     PFFKVPNVLVVTPDNLSELNDLERYDNEYSINFIDLGLNKLFNCI"
     gene            complement(11152..12852)
                     /locus_tag="PC494_002679"
     CDS             complement(11152..12852)
                     /locus_tag="PC494_002679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3913170.1"
                     /translation="MKRYLKTYGVALIIVIIYAFIKLPVLRLDFTSLFSVGIIFFVVA
                     GILDMMLDRNERASKMAKYNFSIAIALLVYIVVVPFITSTPVLHAKSYRELLGKVTES
                     KFTDDISPVSVNDIRLVDEDMAMKLGDKKLGEVPAIGSVSKLGKFHIQNVDGELYWVA
                     PLVHRDIIKWITSLSGTSGYVKVSASNPQDVQLVQEIDGKPIKIVYQPEAYLHQDLQR
                     HLYIHGIVNVGMTDFTLEINDEGRPYWVVSLYEHKIGYGGANATGIATVDAETGKINV
                     YDVKNTPKWVDRIQPQSFVTDQIKDWGVYVNGFLNSVISEKGVLVPTEGTSLVYGNDN
                     RSYWYTGITSSGGDESTIGFMLVDSRTKEARLYKQPGATETAAMKSAEGNVQEKNYEA
                     TFPVMYNILGQPTYVSSLKDKAGLVKRVAFVSVEDYNVLGIGEDKNEALRNYKDALES
                     KGNDLKLDNDLKDEVLEGTVTRISPDVRGGNTNYYVTLDSNKDIIFRATSKVSSELPL
                     TQVGDKVKISYSKEESGVIEMSEFDNLNIANFEDKKAKEKTGTDENTDSKDSENQGNV
                     "
     gene            complement(13249..13812)
                     /locus_tag="PC494_002680"
     CDS             complement(13249..13812)
                     /locus_tag="PC494_002680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3913171.1"
                     /translation="MNKVYIVTTYTGTILSYLIRNISKKLYTHVSISLNENLKPMYSF
                     GRLNPRNPFIGGFVEENINQGLYAIRKNTVCRVYSLEVDNLQYENLYKNIKLISDYRE
                     DYYYDTMALIYLLMNIQRQSEYKYVCSNFVADMLEKSEIDILNKQAFEVTPNDFYNLS
                     GLTLEYEGLLSEYNSRQHSYVSKIANI"
     gene            complement(13971..14684)
                     /locus_tag="PC494_002681"
     CDS             complement(13971..14684)
                     /locus_tag="PC494_002681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2140 domain-containing protein"
                     /protein_id="HDF3913172.1"
                     /translation="MGKVAKILLSLIVIVLVLVGIVVYILTPKERYDVSSQNNKIIDE
                     EYLSKGSYINSMEVVKNPLRMVGKISVSEEEFKNLIYTLMQKHGINELENNFVEMKNG
                     KIKVAGPYKVFGLVNSQYELELRPTLKDGNLVVSLENVKIGKFKLSDKMLEKILSNYN
                     KKVPFEVNGNKITLEKSYLYPITLKNISIKKGNVDLDMEVEIDLKSQINGALGYLKDS
                     GKVQDILNHLINLKKTSVG"
     gene            14976..16640
                     /locus_tag="PC494_002682"
     CDS             14976..16640
                     /locus_tag="PC494_002682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--tRNA ligase/YqeY domain fusion
                     protein"
                     /protein_id="HDF3913173.1"
                     /translation="MSNETNSSNFIKNIIINDLETGKHDSIITRFPPEPNGYLHIGHA
                     KSICLNFGLAKEFNGKANLRFDDTNPLKEDVEYVESIKEDVKWLGFDWNELNFASNYF
                     DEMYKRALILIKKGKAYVCDLTQEEMREYRGTLTEPGKESPHRNRTIEENLDLFERMK
                     NGEFKDGEKTLRAKIDMSSPNINLRDPIIYRISHSTHHNTGDKWCIYPMYAFAHPIED
                     AIEGITHSICTLEFEDQRPLYDWFVKECEMENIPRQIEFARLNINNTVMSKRKLKQLV
                     DEGIVDGWDDPRVPTISGIRRKGYTAEALRNFCSEIGVSKVNSTVDSQMLDYFLRENL
                     QPKAPLTMGVLRPLKLIITNYPEDKIEMLEIENNAKDESQGKRLVPFSRELYIEQDDF
                     MEEPVKKYFRFFPGNEVRLKGAYFVKCTDVIKDENGNVVEIHGTYDPETKSGSGFTGR
                     KVKSTIHWVDAKSAIPCEFRLFEPLILDDIPENEGKHFLEQINPNSLEILQGFVEPTQ
                     IKDAKPFDKFQFVRNGFFSIDNKYTTDEKFVFNRIVPLKSSFKPGK"
     gene            complement(16747..17646)
                     /locus_tag="PC494_002683"
     CDS             complement(16747..17646)
                     /locus_tag="PC494_002683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YegS/Rv2252/BmrU family lipid kinase"
                     /protein_id="HDF3913174.1"
                     /translation="MKKVKLIYNPNSGEKKILSNLDTIIELYQEKNYLLIPYRLTIKE
                     PVKNAFKEVDSSYEHILIAGGDGTVDLVVNAMKELDIKIPIGILPTGTANDFSNALQI
                     SFDIKEAINEIINSKPKKIDIGKVNNKYFINVASAGMFTDVSQRINTDLKNSFGRISY
                     YIKGIEEALYMRKFKIKVSSEEMYYDGDMYLMLIFNGKTAGNINLAYKAEIDDGYLDV
                     IIFKGMPIPKSIPVLISVLRGDYLDQYNGNEILYFKTKKVHIECEDSLITDIDGEKGP
                     DFPLNIECIKDGIEVMGICSEKS"
     gene            complement(17673..18311)
                     /locus_tag="PC494_002684"
     CDS             complement(17673..18311)
                     /locus_tag="PC494_002684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003356606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate utilization protein"
                     /protein_id="HDF3913175.1"
                     /translation="MDQNLNWLNEKRIEKTIKSLENNNMKGYLVSNKEELLKKIEEIV
                     KAGSLVGCGGSMTLFETGVIDFIREKYNFLDRYAKDIKPEEMKEIYRKSFSADAYFTS
                     TNAITEDGELYNLDGNGNRVAAMIYGPDKVIVIAGVNKIVKDVDEAIKRTKTIAAPAN
                     CKRLSTNTGCKTTGICIDCSSPGRICCSYTLIKRQLTPERIHVIFLNEDFGY"
     gene            complement(18652..19650)
                     /locus_tag="PC494_002685"
     CDS             complement(18652..19650)
                     /locus_tag="PC494_002685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4003 domain-containing protein"
                     /protein_id="HDF3913176.1"
                     /translation="MEQSFINGKVNLLIENYKALNEVKGSWQMGLIQHSCALAFTLKN
                     KRISPRLVEERIELIKKNTGLFSNFRGYNMFYMATLLSFESNPESSFKMILDIYKELK
                     SEKFWGDTYLPLTASIVYENREKMDYLTCISKMKIIYDYMRKKHPFLTSSDDYCNIAL
                     IAIHSKNLDEDLEYIEKCYEFLNENGFYKGNDLQALSQILLFSDDRTMLKCKKTIELK
                     KAFKENDCKMNYYGYPIIGAISLLDYREDEIIEEIKNVSNKLKEEKGFGNWSLGKSNR
                     VMISSAIVASIYADLIRNENNIGSITNNIFLNIVVAIQIACVMAATSAAIASSSSN"
     gene            complement(19748..20323)
                     /locus_tag="PC494_002686"
     CDS             complement(19748..20323)
                     /locus_tag="PC494_002686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3913177.1"
                     /translation="MKLKEALITCVVCSVCLTPLLVNGETKIDADHCKESIVNIDTIV
                     KSGKSFNSKYNQGMEDYKNSDEYKLKVQKEKLQNQLGIKIKKLVPITFEVSYYTSLNQ
                     ENGYGAITATGDDLEDGFVANNHLSFGTKIIVDGKLKTVMDRGSSKYFSNSNAIDVFV
                     PKWSNESESEYYDRVNNMGRHYKKGYIIVEE"
BASE COUNT         6755 a         3379 c         2124 g         8227 t
ORIGIN      
        1 gtaacaactc tctctagctg ttacctcata tatttatcta tatctttagt attaagtttt
       61 ttaatttcta cttttttaat tatcaatttc tgtatgtaga tatactaaac cttccaactt
      121 gagatttaaa taacttttca atctcataaa ctattctata caccttattt tcgtactcta
      181 aatcataata cacatttatt tcacctatac tgtttacact tattgtataa tgttcttttt
      241 ctattataca tatgcttcca aaatctgaca ggtcattatc tatcaatttt aactgttttt
      301 ttatttttga aaaatctaat cttggaaata tgtcattagg ataaaaactt ttattatata
      361 caagcatttc atccacccct tatttattct atttatatca ttttataccc taattaataa
      421 tttattaatc atctttttcc atattattca aattctctta tataaaaaca aaatcaattt
      481 agaatatgta ttattaaata taaagtgact caatctttat ttaataagaa aaaacattta
      541 tattacatat agttaatata aaactaatag ttaatgaagc attgcaatag gggggtattg
      601 tatttacatt ccatatagtt aatataaaac gccaagtaca ataataaaaa ataaagaaac
      661 tgtaatattt acattccata tagttaatat aaaactagta gaaagaaata aacttttttt
      721 agggaataat ttatttacat tccatatagt taatataaaa cgatttgtaa cattaaaaaa
      781 gaataaaact ttctcagatt tacattccat atagttaata taaaacgaat aaccaacccc
      841 taatttttta gcaatttgtt cctatttaca ttccatatag ttaatataaa acgatgtaat
      901 aaatgagtat tcagtgcatt tcaaaaatta tttacattcc atatagttaa tataaaacat
      961 tgtatgattt atttttatag cggtactcct gggagattta cattccatat agttaatata
     1021 aaacgagtct aaattacaag cagaagcgga aaaaatgata aatttacatt ccatatagtt
     1081 aatataaaac gtggttggaa cttataaaaa agatgctgat aagttattta cattccatat
     1141 agttaatata aaacgttctg ttgcaacttt tgaaatgtat tgaccaagta tatttacatt
     1201 ccatatagtt aatataaaac aattgataag caaagtcaaa aataaacatt ccttttggta
     1261 tttacattcc atatagttaa tataaaacgg attttaaacc tccttttgat gttcctgcta
     1321 gtagatttac attccatata gttaatataa aacggagatt ctggtgttat taatattcag
     1381 attccttatc atttacattc catatagtta atataaaact tagattttta gagtgcaaca
     1441 tgaaaaaagg tctttaattt acattccata tagttaatat aaaactattt agacaagtaa
     1501 aaaaccactc tgcgcaaaag agatttacat tccatatagt taatataaaa ccctactaaa
     1561 cacgctttag agggaaacaa gttagattta cattccatat agttaatata aaactaaagt
     1621 tactcttaat aatatagata gtcttgatgt atttacattc catatagtta atataaaacg
     1681 ctgatgaaaa agagcgtcaa caacttcaaa aagaaaattt acattccata tagttaatat
     1741 aaaaccccaa aataaattaa gtatttccaa tacttataca tatacaattc tcctaaactt
     1801 gcagtgagcg agcaatagtg caattgataa cagttatcat acactctcaa cgctttatat
     1861 ttcaactatt aaaccctact ttatcacaaa aatcgctcac tgcaaaactt ttatattttt
     1921 attatatcat aaaactcata ctataaaata aaaatgggat aattttacaa actaaaagca
     1981 tctacattct tataagtatt tattatattc tctattccaa tgattccttt ttctttttat
     2041 tgcatccttc ctatgtaatc gcaccttagc tcaataagtc ttttattttc attaacaatt
     2101 ttttaaatta ttcaaaatca tcaaattttt catcttatac agttaaatca aaatacgtgt
     2161 tatatctctt tatctatata cttttcttcc ttccatttct tttcctcttt atacattttc
     2221 actttgttac tttacaatct caaggttatt atctgctatt aaagttttat ctttccaggt
     2281 ttcacaaaaa taaattgaat aagtgcaaaa ataacagata caaaaccata actattttct
     2341 tttctataaa aaaatatata atcaacaaga aatataataa atgaaaataa ctatgaataa
     2401 atactctcat ttagaagaaa tagacaaaga tattccttaa aatttaagca aaatattgtt
     2461 taaataaaaa aactgactgt cagttaaatg ccagtcagct attttatata ttttatccaa
     2521 acatcactat atttgaacat tttaataatt aataatactt attaatatac aaactttact
     2581 catacacaga atatcttttc caaatttgct ctaaatcatc aaaatgctgt ttaatatctt
     2641 ctttttcctt catcccaaca gatatagcaa gggcatttga aatactaaga gctggaacta
     2701 gagaatctac aaatgaagcc atattactct taactagaag agtgttatct gcaagtgatg
     2761 ctactggcgc aaataagcta tctgttaatg atattacatg ggctcctttt tccttagcat
     2821 aattgacaat ttgataagat ttcttagaat aacgagggaa actaatagca actattacat
     2881 cttcttcatt tattcttaca atctgctcaa aagcatctcc catatccatt ctaattatat
     2941 gaacattgtc aagtattata tctaagtaaa aacctaaata ttgagctact acaaaagaac
     3001 tcctcattcc aagtatatat atttttctcg ctcttaaaag tttgttagaa gcttctttaa
     3061 acgctctctc gtcaatttct tctagtgtag accttatatt atctatatca ctttttaaaa
     3121 ctttgtttag tattgcaaaa tcatcggaat aatcatgtgc catttcaact ctttgtactg
     3181 tagttagttt attttttatg agttcttgaa gtgcagcttg taatttagga tatccactat
     3241 aacctaatgc atttgcaaat cttacaactg tagactcact tactcctaca gtttcaccca
     3301 atttacatgc agtcataaat gcaactttat cataattatt taaaatgtat tgtgctataa
     3361 gtttttgacc cttactcaat ctcgtatatt gagattgtat atttgatatc aaatgtttac
     3421 tgtccttcat ttcatttgtt tcttccattt ttttctcctt ttagttatat aaactatttt
     3481 gttttattaa cactgtcttt ttctctaaaa attttatttt ttatctcaat ttcatcttag
     3541 tttttatcat agcttcttaa actcataaaa ttctaacttt tctgtacctt atatttcaca
     3601 tagtattttc gattaaattt attataccat ctttccttgc attttttaat atttatccaa
     3661 tatttctttt aaatttttca atttttactc atttaaaagt tatctatctt attttgcata
     3721 tttagatgta tattttgttt tgagaataag ctgttgtata cttattattt aaagtatttt
     3781 taataggtca cactatatat attaactctt aatacaatct tgtcaagttt tttagtattt
     3841 attatgcttt tttcttttca attaaaatca attgtggtgg gttattgact tgatttaaaa
     3901 acttagattc taaaacatta aattcatctt gatttaaatt attgacaagg ttatatatgc
     3961 aatctttttc ttcttgacct ccatcatgcc ctgtatatat ggcaatgctt attactccat
     4021 tttcttttaa catttctaaa cttaacttta tagcctttaa agttgtatct ggtttggtta
     4081 taattgaatg tttcgctctt ggaagataac ccaaattaaa taaaacacat gaaacttctt
     4141 cttttatata ttgattcatt ttttcatgcc catcaaatat caattttact ctatctgtat
     4201 atccttcttt ctctagtttc tttcttgtag actttattgc ttcttcttgt atatcaaaag
     4261 catatacaaa gcccttttct ccaaccttct cagctagata ccttgtatca tacccatttc
     4321 ccatagtagc atcaattact atgtcacctt catttataat attttctaaa taaaatttat
     4381 ttatatctgt aattttagtt aaatactttg catatgccat aatactattt ctccctacta
     4441 ttaactttat ttcatttttt ctcaatttat ttttatctta ttttattgat tttaaatatt
     4501 ttatttcatc ttctgttagg tatctatatt ctccaacttt ggtgtctttt aatactattt
     4561 tccccacaga aatccttctt aaatttaaaa ctggatgatt tatagctttg cacatttttc
     4621 ttacttgtct atttctaccc tcatgtatag ttatttcaca cactgaataa tttttttctt
     4681 tattttcttt agttaccctt attttagcag gtgccgttgt gtaatcttct atttttagtc
     4741 ctgtttcgaa ttgtcttatc tcatcatcac ttataattcc cttcacactt gccacatacg
     4801 ttttatcaat ttcatgtttt ggatgggtaa gcttatatgt taaatcgcca tcattagtaa
     4861 gtattaataa tccactagtt tcataatcta atctccctat tggatatact ctttccctta
     4921 catctttaag tatgtctatt acactgggtc tattgaattg gtcttttact gtagttatat
     4981 atccctctgg tttatttaat actatatata tataattttc acttggtttt acttttttat
     5041 tatcaaattc tactatgtct ttttcttcat caatattaaa agataactct tttactacac
     5101 ttccatttac ctttattctt cctccaagaa ttatttcttc tgcttttctt cttgatgcta
     5161 ttccacaaga agctatatac ttattaattc tcatacttaa tccttcctta tcttaaatta
     5221 tgtgtgttta atatttttat caatgttaat tttgctacat tattatacta tactagacct
     5281 taattaaaaa caagcaaaaa aattatttaa ttttcctaaa taattgtaat ttcttttcac
     5341 atactattaa tatgtaatag ctgactaaac actattttaa ggaagtgatt attatttcaa
     5401 aggaaaatat aaaatattat ttaatagtcg tgtttattgg aattttattt tttaaattta
     5461 ttaatactcc atcagacttt atatctagta ttgaaggatt cttaaagttt tttagcccat
     5521 ttttattagc tattttactt gctttacttt taaatccact tgtgatgctt tttgaggtaa
     5581 aattcaaagc acatagactt ttagccattt ttttatctta tatatttata ggttttattt
     5641 tagcctttgc cattaggtta ttaattccat caatagctaa tacattaaat agattgataa
     5701 atgaaatgcc tatgtatact gattatatag atagttttat agaaaaaaat atgtcaaaca
     5761 tagattttct aaaaacttta attcctcata tacaacatag tttagataat ttattaaaag
     5821 aagcaagtaa ttttgttggt aaaattccta aaaatttctt aatctataca cttagtatat
     5881 cttctatgct atttaatatg acaatgggat ttatactatc tatatacatt atatatgata
     5941 aagaaaaaat tgcattggga tttaagagat ttctatattc ttctactgct agaaacaagg
     6001 cagataatat tatagaattt tttaggacta ctcatgatat tttctatgat tatttacttg
     6061 gtagaatatt agactctctt attattggta taattgcatt tttaggattt caatttgtta
     6121 tcagaataga aaatgcttta tttttagctt caataatatt cttaggtaat ataattccct
     6181 attttggtcc ttttattggt gcaatccctc caatagccat gactatatta tatagtccac
     6241 aaaaaactat atgggtcatt gcatttctat ttatattgca acaattagat ggaaatttta
     6301 tagaaccaaa agttatgggt aatcaagttg gtataggagc tatatgggta atatctgcta
     6361 ttttggtggg acaatctcta tttggtttca taggagtttt tctttcagta ccaatagctg
     6421 ctgttgtaaa aacttatgtt gataaatata tagataatcg tttacaatag cttatctcta
     6481 ctgtgacttt aatttttagt ttaaaattta actgttattt attaaattat ttctcaaaaa
     6541 atatctctta gtaagaaaaa attgctaaga gatatttttt ataatatata atttgttcat
     6601 taaatttatg catatatttt atacttattg attatttgag ttttgagaat ttccaccact
     6661 atctgaacca ccagtagtat cttgtggagt tggtgctggt gttggattac tattatttgg
     6721 cttttcttga ttttgagaag aactgttatt attgtcagac ttattactat ctgatttttt
     6781 atcattattt ttagaactag atttattatt tttactactt ccactataag aagatttcct
     6841 tgcatctgat tcaactctat acctatcttc tccagccgta tcttttgcct ttttctttct
     6901 ttgttcctct gcttcgtttt gttctttttc taatttagtt aactcttctt tctttttagt
     6961 tgcctcttct ttaataacag aggaaccatt tttgattttc tctataagtt taagttcctt
     7021 gattgcaccc tcataatttt ttaattcttc aaactccgtc atatttgaca ttctcatagc
     7081 ttgcatatac atagctcttg cattctcatt agtactatct tcttccagtg cagaggataa
     7141 tgattccata gcttttttat agttatgttt ttctaaatat gtttttcctt gctctactaa
     7201 atttatttca tcttttttat taaatgaaca tcctacaaga aatatagata atatcgatat
     7261 taataaaatt actcttcctc tcattaaatc cctccttgtc atatacttta aattttatca
     7321 taattataaa gtttttaaaa tattttatat ttattacaag aaatttgtta gtaaaacaaa
     7381 aaataagcag atatgctacg aacgatacaa taaaccaaaa attaatttag agatacatat
     7441 cctagcaaat ctgctcataa taaactttaa tatttaattt ttattatata cttctccatt
     7501 ttatatctct aaagctaata agtcctcata gctttgtctc ttacaaatta tcttatcatt
     7561 tccatcaaat actgatacta ctgctgctct tggtatttta ttataatttg aagacattga
     7621 atatccatat gcaccagttg atgttgttat aagtatatct ccacttttaa tatccattat
     7681 gtttatatct ccaattaata tatctccact ctcacaacat tttccagcta ttgttacatg
     7741 attcatagcc tcatgattaa ttttattcac aatactacac tcataactag cttggtacaa
     7801 cgaaggtctt acattatctg tcatacctcc atctacactt acataaaccc taacatcttt
     7861 tatatctttt atagaaccta ctgtatacaa tgtacttcct gcatttgcaa ctattgatct
     7921 tcctggttct attaccaatg tgggtacttc tattccaagc tctttacatg aagtttctgc
     7981 tttagtgatt atagtttcac aaaactcttt tatagtttta ggtttatctc cttcgctata
     8041 ataaacgcca actcctccac ctaggtcaat ttctgttagt tgtatgttga atttttcttt
     8101 tatttctttt accaagttca tcattatatc cactgtatct atgtatggtt ctacatcaaa
     8161 tatttgtgaa cctatatgag cgtgaagacc cacaagttta atatttttat attcacttaa
     8221 tttttctatt gctctaaata aatctccatt tactaaagca aatccaaatt tagaatctat
     8281 ctgtccagtt tttatataat catgtgtatg agcttctata ccaggagtta ttctaaagta
     8341 tatctcttga gttttacctt tatcttcaca taatgcttca agcaaatcta attcataaaa
     8401 attatccacc acaaatttac ctacacctaa atctaatccc atgtttattt cttctttagt
     8461 cttattgttt ccatgaaaga aaactttttc cataggaaaa tttgatttat aagctgtata
     8521 taactcgcct cctgaaacta catctaaaca catttgttct tcatttataa gattacacat
     8581 gtaaagaggt aaaaaagctt tccctgcata agcaacctta ttttttccct ctctagcctt
     8641 aaaatattct acatattctc tacaattttg tctaactaaa gcttcatcaa atacataaag
     8701 tggagtttga tattttttac taagttctaa acaactcact cctccaatat ataattcatc
     8761 attatttaca gtcatagttc catgaagttt cataatagcc tccccaaatt ttatatatta
     8821 aatacttctg ctattttttc tatagctact tgcttatcat cagaatttat agcacaagtt
     8881 atacgaatct ctgatgtagt tataagtttt atcattatac cattttcatt gaatatctta
     8941 aatactttag cagcaactcc agaagtattt ttcataccaa gacctactaa agaaaattta
     9001 gtgatattat tatcaatcac tacatgttct tcatctgtat atttagatac tatcttttta
     9061 cattctccca actcttcttt tggaactgta aatgatacac ttatcttatc taaaataggt
     9121 gcagtttggc ttatcatatc tacacttata cctatagttg ctatatcttc aaataagcta
     9181 gatatatttt cagctttaaa atcttttatt gttatagaac tgtcatcatc actagtagct
     9241 aatcctgtta ttactttatc ctctaatttc atgtcttttc cccctcttat atatgttcct
     9301 ttttctgtac cacatgtacg tccgacatag atttcaacac catatttttg tgcaagctct
     9361 atacttcttg aatgcattac ttgtgctcct aaactcgcta actcaagcat ttcttcatat
     9421 tcaatctcat caagtttact agcctttgaa tattttcttg ggtctgtaaa ataaattcca
     9481 tcaacatctg tatatatctc acattttcca tttaatttaa ccgcaagagc tacagcagat
     9541 gtatctgaac cacctcttcc aagagtggtt acatcaccat cttcgttgat tccctgaaat
     9601 ccagttacta tcacgacatt tccttcatct aaactatttt taattctgtt tacgtttata
     9661 tcatcaattt gagactttcc atgaagacca ctcgttttta tatttaactg gtaagcatta
     9721 taacttatag ctttacatcc aagtgcattt aatgctattg ataataaaga tgctgaaatc
     9781 atttcaccag tagacattaa agcatctaat tccctcttac taggttcatt actcaattcc
     9841 tttgctaaag ttatatattc atcagtggat tttcccatgg cagacacaac tattaccatt
     9901 tgtggatttt cttttcttcg ttctattata ttttctgcta ttgattttat tttttcagta
     9961 tctgctactg aacttccacc atatttttga acaattatac tcatgctttc tccccctcaa
    10021 gctaaatttt gataaataaa aacgcccaaa ggtatacttt ggacgtgtaa atttcataga
    10081 ccaagtaacc ttgtagctca ccactttaaa agtgacagcc ttatgcatat tctgcataag
    10141 tccagaaaat ttgtccgtca acaaaatttc ttcggctata taccctttca tcaattatca
    10201 acgcttacca gctcctattg aatactattg aatacagcta cctctaccct aggctcatta
    10261 tttttaatta atttattaat atagttttat catattctat ataatattgc aacaattatt
    10321 ttacaaaatg tggcaaatcg atagttttct tttctaaagt tagcttatat acaattaaat
    10381 agtttattta atcctaaatc tataaaattt atgctatact cattatcata tctctctaaa
    10441 tcatttaatt cggatagatt atctggtgta actaccaaaa cgtttggtac tttaaaaaat
    10501 ggaattgtag atttatctat ttttttagaa agattttcgt atttagaaat gtctatttca
    10561 ttatttaagt caacatcaac taaaacttgc tttatattac caaattggtc tgtatattca
    10621 ataaataaat cgtatttcac atcatctaca ctaacatttc ggtaaaatct ttttacatca
    10681 caacctgcag tattgattct aacaactaat tctgatccta ctagagcctt tattaaatca
    10741 tctcccttaa aaagtttact accgtttaaa tagtatacat aagagaggtc tttataatta
    10801 taataatcca catcacaagg atattttttt agtgtatatt cactacacat ttttctcaaa
    10861 gtttttttaa aatttttttt attgtatctt ttttggtctc cataaatttt tctaaattga
    10921 gactctgtaa cacatctaac cctgctaatt aaaagtaata tctctttttc catattcgtc
    10981 atagtacatt ctccttgaag tattatttgc aaagttgtac taatattata ttaattttat
    11041 gacattaaat ttacaaagaa ttaaaataaa atagctaatt tttatagaat taaattctat
    11101 aaaaattagc tatcactatg ttaaatacta ttatcaatct ttttatttaa attatacatt
    11161 accttgattt tcagaatctt tggaatctgt attttcatca gttcctgttt tttcttttgc
    11221 ttttttatct tcaaagtttg caatatttag gttatcaaat tctgacattt ctattacacc
    11281 agattcttct tttgaatacg atattttgac tttatcacca acctgagtca atggcaattc
    11341 gctagatact tttgaagtag ccctaaatat tatatcttta tttgaatcta aagttacata
    11401 ataattagtg ttaccacctc gcacatctgg gcttattctt gtcactgtgc cttctaatac
    11461 ctcatctttt aaatcattat caagttttaa atcattaccc ttagattcta atgcatcctt
    11521 atagtttctt aatgcttcat tcttatcttc acctattcca agtacattat aatcttcaac
    11581 agatacaaat gcaactctct taacaagacc agccttatct tttaatgatg atacatatgt
    11641 tggctgaccc aatatattat acattacagg gaacgtcgct tcataatttt tttcttgaac
    11701 attaccttca gctgatttca ttgcagccgt ttcagtagct cctggttgtt tatataatct
    11761 agcttctttt gttctagaat caactaacat aaatccaatt gtagattcat ctccacctga
    11821 agatgttata cctgtatacc aataagacct gttatcattg ccataaacta atgatgtacc
    11881 ttctgttggt actaaaactc ccttttctga tataacagag tttaaaaatc cattaacata
    11941 aacaccccag tctttaatct ggtctgttac aaagctttgt ggttgtattc tatccaccca
    12001 tttaggcgtg tttttaacat cataaacatt tatttttcca gtttctgcat caacagtggc
    12061 tattcctgtt gcatttgctc ctccatagcc aattttatgt tcatataaac ttacaaccca
    12121 ataaggtctt ccttcatcat ttatttcaag agtgaaatct gtcataccaa catttacaat
    12181 accatgtatg tataaatgtc tttgtaaatc ctgatgtaag taggcttctg gttggtaaac
    12241 tatctttatt ggctttccat ctatttcttg aactaattgg acgtcttgag gattactagc
    12301 tgatactttt acataaccac ttgtaccact tagagatgtt atccatttaa ttatgtctct
    12361 gtgaacaaga ggcgctaccc agtacaactc tccatctaca ttttgtatat gaaattttcc
    12421 taatttggat acactcccta ttgcaggaac ttctccaagc tttttgtcac ctaatttcat
    12481 tgccatatct tcatctacaa gacgaatgtc atttacactg acagggctaa tgtcatcagt
    12541 aaatttactt tcagttactt ttcccaatag ttctctatat gattttgcat gaagtacagg
    12601 tgtagaagtt ataaagggaa ctactacaat atacacaagc aaagctattg ctattgaaaa
    12661 attatattta gccattttag atgctctttc atttctatct aacatcatat ctagtattcc
    12721 tgctacaaca aagaaaatta ttcctactga aaataaagat gtaaaatcta atcttagtac
    12781 aggtaattta ataaatgcat aaattattac aattattaat gcaactccat atgttttaag
    12841 atatcgtttc atttaatact cctctctaaa aaatgttatt attactatta tatccatata
    12901 tttacaaaaa ataaatattt atcatattta ttatatatta agatatcttt atatatttat
    12961 agttctgctt attcaactat atttaacatt atacgtgtat gtataaatac tttttataca
    13021 ctgtttgtac tatccatccc gcacctaaag gagtgggatt tttgcactat tctgtattat
    13081 atatatccaa aaatattata aaaatacaaa tattagcaga aatttaaaaa ctgaagaaag
    13141 tattctaact aagatttaca aattcttaat cctatcgaag ttaaactact atcttcagcc
    13201 taattatcta gcaatatttt tttatatgaa aaactctaaa tcaagttttt aaatgtttgc
    13261 gatttttgat acataagaat gttgtctaga attatattct gataataaac cttcatactc
    13321 taaggttaag ccagataaat tataaaaatc atttggcgtt acttcaaatg cttgtttatt
    13381 taaaatgtct atctcacttt tttctaacat gtcagcaaca aaatttgaac atacatattt
    13441 atattcagat tgtctctgaa tattcattag taaatatatt aatgccattg tatcgtaata
    13501 gtaatcttct ctataatcac taattaattt tatattttta tatagatttt catattgtaa
    13561 attatctact tctaacgaat ataccctaca cacagtgttt tttcttatag catataatcc
    13621 ttgatttata ttttcttcaa caaatcctcc aataaatgga ttccttggat ttagccttcc
    13681 aaaagaatac attggtttta gattttcatt taatgatatt gacacatgtg tatacagctt
    13741 tttacttata ttccttatta agtaagataa tatagttcct gtatatgttg ttacaatata
    13801 gactttattc atcatttccc cccaatctag taactaaata atattataca cttacaattt
    13861 aatatcataa gatattctaa cataataaat gtggttttac aaattttgat tttaaggtac
    13921 tttaatatta tataatataa taaaaatata aatataagtt ttctatattt ttaaccaaca
    13981 gatgttttct tcaaattaat cagatgattt agtatatctt gaacctttcc agagtccttt
    14041 aaatatccta atgccccatt tatttgtgat tttaaatcta tttctacttc catatccaaa
    14101 tcaacatttc ctttttttat agatatattt ttaagtgtta ttggataaag ataacttttt
    14161 tccaaagtaa tcttatttcc attaacctca aatggaactt ttttattgta gttacttaat
    14221 attttttcta gcattttatc acttagttta aattttccaa ttttcacatt ctcaagactt
    14281 acaactaagt ttccatcctt taaagtaggt ctcaattcaa gttcatattg actatttacc
    14341 aaaccaaata ccttatatgg tcctgctacc tttattttac catttttcat ttcaacaaaa
    14401 ttattttcaa gttcattaat tccatgcttc tgcatcaatg tatatattaa atttttaaac
    14461 tcttcctctg aaacagatat ttttccaacc attctaagtg gattttttac tacctccata
    14521 gaatttatat atgagccttt tgataaatat tcttcatcta tgattttatt attttgtgaa
    14581 ctaacatcat atctttcttt tggtgtcaag atatatacaa caattcctac aagtactaaa
    14641 acaataacaa ttaaacttaa caaaatcttt gcaacctttc ccataatcgt ctcctttaca
    14701 aatctgtcat cagatttaaa ataaatttag ataactaact tcacataata ttcttaacaa
    14761 tatacatact ataatacagt cttttaaaaa ttaattcaac caatctaatg ttttgtaaat
    14821 aaactgtaaa aacatgtttt tagtataaaa gttaatattt tgcataatac tcttaattac
    14881 acctttattt ttttctaatc ttggattaaa attaatatta tgcaatacag tgtagtgttc
    14941 tgtattataa tcaaattaaa taggaggtat agaatatgtc aaatgaaacg aactcatcta
    15001 actttataaa gaatattatt ataaacgact tagaaacagg aaaacatgac agtatcataa
    15061 ctcgttttcc acctgagcca aacggatatt tacatattgg tcatgcaaaa agtatatgtc
    15121 ttaattttgg attagctaag gagtttaatg gaaaagctaa tttaagattt gatgatacaa
    15181 acccattaaa agaggatgtt gaatatgtag agtccataaa agaagatgta aagtggttag
    15241 gatttgattg gaacgagtta aattttgcat ctaactactt tgatgaaatg tataagagag
    15301 ctttaatact aataaaaaag ggtaaagctt atgtatgtga tttgacacaa gaggaaatga
    15361 gagaatatcg tggtactcta actgaaccag gaaaagaaag tcctcataga aacagaacta
    15421 ttgaagaaaa ccttgattta tttgaaagaa tgaaaaatgg tgaatttaaa gatggtgaaa
    15481 aaacattaag agccaaaata gatatgtctt ctccaaatat aaaccttaga gacccaatta
    15541 tatatagaat atctcattca acacaccata atacaggaga taaatggtgc atatatccta
    15601 tgtatgcttt tgctcatcca attgaagatg caattgaagg aataactcac tctatatgta
    15661 ctttagagtt tgaagaccaa agacctcttt atgattggtt tgttaaagaa tgtgagatgg
    15721 aaaatatacc tagacaaata gaatttgcta gacttaatat aaataatact gtcatgagta
    15781 aaaggaaatt aaaacaactt gtagatgagg gtattgttga tggttgggat gaccctcgtg
    15841 ttcctacaat atccggaatc agacgtaagg gatatactgc agaagcattg cgcaatttct
    15901 gtagtgaaat aggggtatca aaagttaact ctacggtaga tagtcaaatg cttgattatt
    15961 tcctaagaga aaacttacaa ccaaaggctc ctcttactat gggagtttta agacctttaa
    16021 aacttattat aactaattac ccagaagata agattgagat gcttgaaata gagaataatg
    16081 ctaaagatga atctcaagga aagagattag ttcctttctc tagagaattg tatatagaac
    16141 aagatgattt tatggaagaa cctgttaaga aatattttag atttttccca ggaaatgaag
    16201 tccgtttaaa aggtgcttat tttgtaaaat gtactgatgt aattaaggat gaaaatggaa
    16261 atgtagttga aatacatggt acttatgacc ctgaaactaa gagtggctct ggctttacag
    16321 gacgtaaggt aaaatctaca atacattggg ttgatgctaa atcagctatc ccatgtgaat
    16381 ttagattatt tgaaccatta attcttgatg atatacctga aaatgaaggt aaacatttct
    16441 tagaacaaat aaatcctaat tcattggaaa tattacaagg ttttgttgaa cctacacaga
    16501 taaaagatgc taaacctttt gataaattcc aatttgttag aaatggattc tttagtatag
    16561 ataataaata tacaactgat gaaaaatttg tatttaatag aatagttcct ctaaaaagtt
    16621 cttttaaacc aggtaaataa tcttacaatc aaaaaatgaa gacttaaaat ataaattact
    16681 tctactataa ataaacttag ttagaagtaa ttttttattt gagtcttcat catttacttt
    16741 aaatgattaa cttttttcac tacagattcc catgacttct attccatctt ttatgcattc
    16801 tatgttaaga ggaaaatctg gtcctttttc tccgtcaata tctgttataa gtgaatcttc
    16861 acattctata tgcacctttt tagttttaaa gtatagtatt tcatttccat tatattgatc
    16921 taaataatca cctctaagca cacttatcaa aactggtatt gattttggta ttggcattcc
    16981 tttaaaaata attacatcca aatatccatc atctatttca gccttatatg ctagatttat
    17041 atttcctgct gttttgccat taaaaatcaa cataagatac atatctccat cataatacat
    17101 ttcctcagaa gatactttta tcttaaattt cctcatatac aatgcttctt ctattccctt
    17161 tatataataa gaaattcttc caaatgaatt ttttaagtct gtgtttatcc tttgtgatac
    17221 atccgtaaac ataccagcac ttgcaacatt tataaagtac ttattattga ctttccctat
    17281 gtctattttc tttggttttg aatttatgat ttcatttata gcttctttta tatcaaatga
    17341 aatttgaaga gcatttgaaa aatcatttgc agttcctgta ggcaaaattc caattggaat
    17401 ttttatgtct aattctttca ttgcatttac tactaaatct acagtaccat caccaccagc
    17461 tatcaatatg tgttcataag aactatcaac ttccttaaat gcattcttta caggttcttt
    17521 aatagttaat ctatagggta tcaataaata atttttttct tgatataatt ctatgatagt
    17581 gtctaaattt gataatatct ttttttcacc tgaattagga ttgtatataa gttttacttt
    17641 tttcattatt tctccttact cattttattc ttttagtatc caaaatcttc atttaaaaaa
    17701 atcacatgta ttctttctgg tgttaattgt ctttttataa gtgtataact acagcatatt
    17761 cttcctggac ttgaacagtc tatacatata ccagtagtct tacatccagt atttgtactt
    17821 aatcttttac aattggctgg agcagctatt gtttttgttc tttttatagc ttcatctaca
    17881 tctttaacta ttttatttac tcctgctata actattactt tatcaggtcc atatatcata
    17941 gcagcaaccc tattcccatt cccatctaaa ttgtaaagtt ctccatcctc tgttatcgca
    18001 ttagtacttg taaaataagc atctgcagaa aatgactttc tatatatttc tttcatttct
    18061 tctggtttga tatcttttgc atatctatca agaaaattat atttttctct tataaaatca
    18121 atcactcctg tttcaaataa ggtcatagaa cctccacatc ctactagaga acctgcttta
    18181 actatttctt caattttttt aagaagctct tctttgttac ttactaaata ccctttcata
    18241 ttattgtttt ccaaagattt tattgttttt tctattcttt tttcattaag ccaatttaaa
    18301 ttttgatcca ttttaacttc ccccttattt ttaatatgta cttaattatt tataaacttt
    18361 attttcttta taagtttatt ttagtacatc taaaaaaaaa tacaatataa aacttaaata
    18421 gttttacata attttttcca aaataactta ctcaatcaaa aaaggaaagt agatgtacta
    18481 ttctactttc cctatattgt atgtagtatt atatattgcc taaaatctat atattaatta
    18541 tatgtttcat attatatgaa tatcacagtt aattaaaatg taatactatc ttctttttaa
    18601 acatataaat tgtattatta aatttaatat atccaacttc aataaatctt attaatttga
    18661 tgaagaagat gctatagctg cacttgttgc tgccattaca catgcaattt gaatagcaac
    18721 aacaatattt aaaaatatat tattagttat agagcctata ttattctcat ttcgtatcaa
    18781 atctgcataa attgaagcta caatagcaga actaatcatt actctattac tttttcctaa
    18841 agaccaattt ccaaagcctt tttcttcttt aagtttattt gaaacatttt ttatctcttc
    18901 tattatttca tcttctctat aatctaataa tgaaattgct cctattattg gatatccata
    18961 ataattcatt ttacaatcat tttctttaaa tgctttttta agttcaatag tctttttaca
    19021 tttgagcata gttctatcat cactaaataa aagaatttgg gataatgctt gtaaatcatt
    19081 tcctttataa aaaccatttt catttagaaa ttcataacat ttttctatgt attctaaatc
    19141 ttcatctaaa ttttttgaat gaattgcaat aagtgctata ttacaatagt catcactaga
    19201 agttagaaat ggatgttttt tcctcatgta atcatatatt attttcattt ttgatataca
    19261 tgtaagataa tccattttct ctctattttc ataaactatt gatgctgtaa gtggtaaata
    19321 tgtatcgccc caaaactttt cacttttaag ttctttgtat atatctaaaa tcatcttaaa
    19381 actactttct ggatttgatt caaacgaaag tagtgttgcc atataaaaca tattatatcc
    19441 tctaaaatta gagaataatc cagtattttt tttaataagc tctattcgtt cttccactaa
    19501 tctaggactt attctcttgt tcttaagggt aaatgcaagt gcacaactat gttgtatcaa
    19561 tcccatttgc caagaacctt taacttcatt taatgctttg taattttcta ttaataagtt
    19621 tacttttcca tttataaacg attgttccat attgccctcc tagtaatata tctcattgta
    19681 ctaatagttt tatatttatt atatatatat taaatactac aatcaataca tattacttca
    19741 aagaacatca ttcttcaaca ataatgtagc cttttttgta atgtcttccc atattattga
    19801 ctctatcata gtactctgat tcactttcat tactccattt gggcacaaat acatctattg
    19861 cattagaatt actaaaatat ttactagacc ccctatccat aacagttttt aattttccat
    19921 ctacaataat cttagttcca aaacttaagt gattgtttgc tacaaaacca tcttctaaat
    19981 catctcctgt agcagttatc gctccatatc cattttcttg attaagactt gtgtaataac
    20041 taacttcaaa agttataggt actaacttct ttattttaat acctaactga ttttgtagtt
    20101 tctccttttg tactttcaac ttatactcat cactattttt ataatcttcc ataccttgat
    20161 tatacttgga attaaagctt ttacctgact ttactatagt atctatattt actatagatt
    20221 ctttacaatg atctgcatct atttttgttt ctccatttac caataatgga gttaaacata
    20281 cactacatac aacacatgta atcaatgctt ctttaagctt cataaattcc ccccttatta
    20341 ttttgatata ttagcatatt taatattata tgtctacatt tagatttaaa taccacaccc
    20401 atttgcttta agaagttgtc ttatatttaa ttcaccttaa acacttataa atcctctatc
    20461 ttagaatcat atagaataaa gcttt
//
LOCUS       DAMKNB010000067        19318 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.069, whole genome shotgun sequence.
ACCESSION   DAMKNB010000067 DAMKNB010000000
VERSION     DAMKNB010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 19318)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19318)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19318
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.069"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            335..913
                     /locus_tag="PC494_002687"
     CDS             335..913
                     /locus_tag="PC494_002687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_126936537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerD family protein"
                     /protein_id="HDF3913178.1"
                     /translation="MGITLSKGQKVDLTKGNPGLKNILVGLGWDTNKYDGGFDFDLDT
                     AAFLTGASGSVTNDGDFVFYNNLKHTSGAVEHLGDNRTGEGDGDDEQIVVDLSKIPGE
                     ISKISFTVTIHDATERRQNFGQVSNSYIRIVDKDTNEELIKYELGEDFSIETAIVVAE
                     IYKHNGEWKFNALGSGFEGGLAALCGNFGINL"
     gene            952..1530
                     /locus_tag="PC494_002688"
     CDS             952..1530
                     /locus_tag="PC494_002688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_126936537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerD family protein"
                     /protein_id="HDF3913179.1"
                     /translation="MAIVLKKGQKIDLTKGNPGLKNIKLGLGWDTNSFDSGYDYDLDV
                     SVFMVGESQRVEKDEDFIFYNNLKHPSGAVEHLGDNRTGEGDGDDEEILVNLETMPKH
                     IQKIAVTVTIYEAAERRQNFGQVSNSYIRVLNSENDEEILRYDLGEEFSIETAITVCE
                     IYKYNGEWKFSAVGAGFEGGLEALCRNYGLNV"
     gene            1616..2245
                     /locus_tag="PC494_002689"
     CDS             1616..2245
                     /locus_tag="PC494_002689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerD family protein"
                     /protein_id="HDF3913180.1"
                     /translation="MSINLSKGDKIDLKKSNPGLSNILVGLGWDPVQQSGGGFFKSLF
                     GGGQADIDCDASVFMLNQEGKLSGIKDLIYFGNLKSACKSVLHTGDNLTGEGTGDDEQ
                     ILVNLDKVPSNIHKLLFVVNIYNCVDRKQHFGMIENAYIRVEDQGNKKEIAKYNLSDN
                     YSEKTTLIVGAIYRKDGSWQFKAIGEGTKDAGLKEVMQNLDRIECAYGI"
     gene            2235..4994
                     /locus_tag="PC494_002690"
     CDS             2235..4994
                     /locus_tag="PC494_002690"
                     /EC_number="7.2.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="calcium-translocating P-type ATPase, PMCA-type"
                     /protein_id="HDF3913181.1"
                     /translation="MEFNNDIKYYNVDKEEVTKDLSVNPEKGLSESEVKTRREKYGLN
                     EFTPKEEGSFWDDLKESLSEPMIVILIIAAVVSAVIGETHDAIGIVGAIAIGIAIGMI
                     TEGRSKKAAEALSKLTENIEVKVLRDGEVHQISKSELVPGDIVYIETGDMVPADGRLI
                     ESINLKIREDMLTGESDDVSKKCDVVVSMEEIESKGAVVVQEPIPAKQINMVFGGTLV
                     AYGRGALVVTSIGDNSEMGKIAQNLSETDEQTPLQIKLGNLGGLIAKVSSAVAGLLFI
                     FMVFQMISKNVLNVDMSGILPFLESIDPVKTAFTVCVALIVAAVPEGLPTMINMTLAI
                     TMQKMAKINALVTKKEACETIGSVSVICSDKTGTLTENRMTVEVAYVDGRYIESSEEE
                     INSYFEENCMINSTADVEHNDGDIKYLGSATECALLLYYKNVDYRQVRKNSNIVAQNP
                     FTSDSKRMTSVIGQDNHHVLLSKGAPEVLLELCSHIQRGKDIVPLTENIKHEILEEIK
                     KLQIKSMRTLGFAYKEISQAEEEAAVTAESDAMNVSAMENNLVFSGFVGIRDPLRKDV
                     IESVNTANKAGVSVKMLTGDNINTARAIGEELGLLKNNMRVVEASYIDTLDDEELKQE
                     IQSISIVARSKPDSKMRIVSALQKSGDVVAVTGDGINDAPALSKADVGIAMGISGTEV
                     SKNAADIILTDDSFSTIVKGIKWGRGIYDNFQRFVQFQLTVNVIAFLVAIISQVMGQE
                     MPFTTIQLLWVNIIMDGPPALALGLEPVRDHVLNRKPVDRKANIISKSMVYTIVLNAF
                     YITAILMLQSTFNFLGVDEAHKGTVMFALFAFSALFNAFNCREFNADSIFPNFTHNKL
                     ALQIIVLTGIAQVIFTQLFQDFFNSVAMDFMTWVKVLCVAASVIVVNEVVKCIIRLVK
                     LKKTA"
     gene            5081..6643
                     /locus_tag="PC494_002691"
     CDS             5081..6643
                     /locus_tag="PC494_002691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YceG family protein"
                     /protein_id="HDF3913182.1"
                     /translation="MGDSKVFEKIFSSQSDRGNYTPSKGYLSYFISYIGLEDEVLYNL
                     EIFKTKQNIDSKKDIALFTDVIANPSDFDIINYFKSGLQKYRTSMEDVDINILGFEEI
                     DYKIKQAMDRVLKEEEKEFTNDRVKQNFIVKIMAWIKIYIGALDINKNEAPKVIFYGD
                     IKKHEVYLLLILYLAGFDVLYLNPNSKSNIDILKSERYNIEFEEANIIEEKISFEERV
                     ILGEKIDKSSVKKAFTVGAEASKRISEELLNDAGFIKPWQLQDRKIKNLLLSSTVDEI
                     SIYWNQPLKLRPGFKFNDAIVEAPNFLSKINGIYNDKNEYIKFLDLLRDSESSTFIEF
                     NGDVDRFSKAFTREAFSLSFLLDSKGAIDKNSVLNNKDYSISTLALNQQIMILEKVEE
                     LLEGSMFLNGLSGEDKIKGLFTVLHMDKKFVHMMNNFDYSLINPKLIIYMYKSIVFDK
                     EIVFLMLLLSKIGFDIIILCPGGENNIENVINNQLIDVHRLDKMVYDLKLNSLENDIP
                     LLKKIFGKRRRF"
     gene            6644..7780
                     /locus_tag="PC494_002692"
     CDS             6644..7780
                     /locus_tag="PC494_002692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxic anion resistance protein"
                     /protein_id="HDF3913183.1"
                     /translation="MGININSFSKDKNSVEVTENLPTAVQEENFDIMEYTNNKKNELR
                     KSKEVEALTSLIEVENPDTILQFGRKASEGVARVSDSLLNTIKLNRNEENSKMLVHLT
                     KIMDKFDLDDFQETKEPNFVQKLFKKANNAIEMMFQKYETLGGEVEKIQIELEQYERD
                     IALSNKQIGAMLNENFEFYNELQKYIVAGEMAIEEMDNEILPFFKQKSETSGDQMDVV
                     NYQELLKVYDMLNQRVYDLRIAENIAIQTIPMLRGMQHNNYGLIRKINSAFVVTLPVF
                     KQCLSQAILLKKQELQAKSLKALDDKTNELLLRNAQNVSTQSAQIARMAGTSSVQIET
                     LEKMYNTIKSGIDETMRIEENNRALIKDNTKRLEELNTTIIYNK"
     gene            7844..8920
                     /locus_tag="PC494_002693"
     CDS             7844..8920
                     /locus_tag="PC494_002693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HpcH/HpaI aldolase/citrate lyase family protein"
                     /protein_id="HDF3913184.1"
                     /translation="MKYFDYICKDDLERIFLKEPEDFSAKTEKDVLKYALGAFLYVPA
                     TQYNMIYKSIIGDVKGVRPLAICLEDAVGVNGELEAIENLRLILKNISNESITNKDGI
                     PLIFVRIKDVEQLLRIKEIIIKNSHFITGILIPKANSELIENCIEALDFMNLQDMYVI
                     PIVETKEFIYNEKKELSFTNLYNAILRHKSRILSIRVGITDILGMYGIRRDKNFSIYN
                     NLICSSFILDIITYLQRPELDIPISGGVSEFFDMTNKDIRNKYIEEILLDKYHGLIGK
                     TVIHPMQIQIVQALSTVSYEDFTDALDILDSTDSKYGVSKGVLGERMNETNPHFLWAK
                     KTLILSKIYGVLNKGVDYEELLKF"
     gene            8898..10136
                     /locus_tag="PC494_002694"
     CDS             8898..10136
                     /locus_tag="PC494_002694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosyltransferase family protein"
                     /protein_id="HDF3913185.1"
                     /translation="MKNCLNFNCEIDIIDNPLNLELNDFLDVGIRNNSKRRFLFISKK
                     LGKHLACKPSEMDNLGKLMATIYNEKNKEESNGTVIAFAETGTAVGHSFFDYLCGDYE
                     FIHTTREQFDELENLEFLEEHSHATDQNLYFGMLNNFKFGDEIILVDDEITTANTCMN
                     IIRKIQSIYPKKKYTICSILNWVSDENLSKVTRLERELDCKIDFVYLFKGNFKFYIDE
                     DIISNYNDNYSITKLETISSDKVNLVVNHIYVDLEDYIGNKKYVKYTGRFGINRREQF
                     RLKEIVKRESKKITMASKESLKNEKEKILFLGTEEFMYIPMLFAKEKENQYDIYYHST
                     TRSPIINIDKNNYPIKSKFMLKSFYNIDIQNYIYNIDKHNFSKCYLFVELNKSENSYL
                     EFIDIIKKTSIKELTIVCCS"
     gene            10190..11278
                     /locus_tag="PC494_002695"
     CDS             10190..11278
                     /locus_tag="PC494_002695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine protease StiP family protein"
                     /protein_id="HDF3913186.1"
                     /translation="MRDFSTYSKDDVIFLLKDISNLIEEEGNKERELKIQNGRHYSEM
                     IPIEYEVSEDYLNLYHEKLRENKDKLAFSIGVMCEKIIKKNGNDVVLVSLARAGTPIG
                     ILAKRYIRSKYNISLPHYTISIIRDKGIDMNAIEYIVKNHPSSKIQFLDGWTGKGTIS
                     KELEKACDELNVKFKKYFDSTLAVLADPAGYSGLYGIREDFLIPSACLNSTVSGLVSR
                     TVLREDLIGKNDFHGAKFYRHLKDKDESMNYIETIEECFKNQFKNISDEVENWESDII
                     TRDGYFDVLNIKEKYNITDINFIKPGVGETTRVLLRRVPYKILVKDLNDKSLDHIFIL
                     AKEKNVEVEQMDLKAYKCCGIIKNMKDI"
     gene            11306..12097
                     /locus_tag="PC494_002696"
     CDS             11306..12097
                     /locus_tag="PC494_002696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD hydrolase family protein"
                     /protein_id="HDF3913187.1"
                     /translation="MIVFSDLDRSIIYSNKFLNADSKYTNIEIYREKEISYISLDTIN
                     LIKQIQYYGMFIPTTTRTVEQFKRIEFNKYGIYFPWSITSNGGVILKDNEILKSWSEK
                     IDKLKCDYEPIESMIHKFKDYLNVDGITNFKVAEDTFFYIVVDLSRFNLDSIKEYTNI
                     LESKNWKFYVSGRKIYFIPKEISKENAIKYLTKELGIEYFYAVGDSIMDYGMLNISNK
                     SYVLKHGDINKNEIENSFISSSFNGMSGTEEILSNILDENCLLNI"
     gene            complement(12212..12766)
                     /locus_tag="PC494_002697"
     CDS             complement(12212..12766)
                     /locus_tag="PC494_002697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HDF3913188.1"
                     /translation="MNIDVGSKIRSLRKSKNISISTLAKNSDLSTGLISQIERNMVVP
                     SIVAMWKISKALDINIGYFFEEIGREDSDIVVKKNNRKKIVTNDSTKFYELLVPNLSG
                     KKIEFILVTLDGHTQKNSEFVTHEGEECGYIIKGKMKITLGNKEYLLEEGDSFYFNST
                     IPHVYENYDDEVCISVWAMTPPSF"
     gene            12962..14164
                     /locus_tag="PC494_002698"
     CDS             12962..14164
                     /locus_tag="PC494_002698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF819 domain-containing protein"
                     /protein_id="HDF3913189.1"
                     /translation="MKSFVSPDNIWVLWAVVTGWAAFSIYLEQKYNWASKVSGAIIAL
                     VGAMLLSNLNIIPVESVVYDQVWGYVVPLAIALLLYQCNIKKIWKESGRLLIIFLVGS
                     VGTVLGAMIGFLALKNVVPDLNIVAAMMTGSYIGGNVNFAAMSGAFDAPGELVSATVV
                     ADNLLMALYFFVLIAIPSIGFFRKHFKHPHVDEMESIGITEGETVAANYWGRKEISLK
                     DIAIAIGSAFIIVAVSVELSTWFKAIIPLSNPFLAMLNTLFGNQYLIITTLTMLFATF
                     MPNFFGDIKGAQELGTFLIYIFFVVVGVPASITLIIQKSPLLLLYCGIMVLINMLVTF
                     IVAKIFKFSLEEAILASNANIGGPTTAAAMAISKGWSKLVGPILIVGTFGYIVGNYFG
                     LLVGNILI"
     gene            14221..15201
                     /locus_tag="PC494_002699"
     CDS             14221..15201
                     /locus_tag="PC494_002699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane dipeptidase"
                     /protein_id="HDF3913190.1"
                     /translation="MIFDGHSDTWADVTIRRLNGEKDVFRRIHLDNFKRANIEGAIFV
                     IWIDPPYDKEPEKRVKQIISSIKDEIEDMKDVVNIVKKYSDIDKGISENKINILIGLE
                     GLSHIGRNIDLLDYFYKEVGARHASLTWNEQNELATGCLGDENRGLSEIGKKAVNKME
                     KLGMIVDVSHLNEKSFWDLMSVASKPVIASHSNARSLCDAKRNLTDNQLKEISNTGGL
                     VGINSFRGFTNSNPKKQDLIHLVDHIDYMVNLIGIEHVSFGFDFSDYLGKETIGSFTG
                     NASVPSVDGLESTHTAQNIVVELENRGYKKKDIELISSGNFYRLFKDILK"
     gene            15444..16397
                     /locus_tag="PC494_002700"
     CDS             15444..16397
                     /locus_tag="PC494_002700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HDF3913191.1"
                     /translation="MKKRYLVIGIIILSYFSLFIGAEDINIMHIFAKNQHKLMIFIMS
                     RIPRLISILIAGVGMSIAGLIMQQISKNKFVSPTTGATIDAAQFGIVICMLLVPTASI
                     FTKTIIAFVFSLVGTFTFMKIIGKLQFKNIIFVPLVGIMFGNIIGSMTDFIAYKYDLS
                     QNVSSWMQGDFSMILKGNYEILYITIPLIILAYIYANKFTVVGMGMDFATNLGLSYKR
                     IVNIGLIIVALVTVCVVVTAGNIPFIGLIVPNIVSLYMGDNIRASIWYTGLLGAIFVL
                     ICDIFGRIIIYPYEISIGLTVGVIGSILFLYLILRRNVNEA"
     gene            16387..17343
                     /locus_tag="PC494_002701"
     CDS             16387..17343
                     /locus_tag="PC494_002701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HDF3913192.1"
                     /translation="MKLSLNQKIYFVSILLFISMALFIIYGIDMNHLEYALSQRIPKI
                     FAMVLGGGCIAFTTVVFQTITNNQILTPSVLGLDSLYVMIQTIIVFIFGSSSSLIINE
                     NYNFIINVAMMIGASLLLYKTLFEKNKNNIFFLILVGMIFGTLFKSATTFIQVMIDPN
                     EFLALQTSIMASLNNINTNVLLIAFIIIIAIIPFIYDEIKYLDVLSLGKEQAINLGVD
                     FDKAVKKMIILIAILVSISTALIGPMTFLGLLLANITREIFKTYKHTYLISGSMLIGM
                     ITLIIGQFFIQHVFKFDTTLSVVINFIGGIYFIQLLLKGANR"
     gene            17340..18095
                     /locus_tag="PC494_002702"
     CDS             17340..18095
                     /locus_tag="PC494_002702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003234487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDF3913193.1"
                     /translation="MIEIKNIFKRYKNKNVVDDVSFSIEKGKITSFIGPNGAGKSTVL
                     SIVTRLIGGDGGEVIIEGKSLTNYSNKELAKKIAILKQSNNITLKLTIRELVGFGRFP
                     YSEGNLTKEDENYIDEAIEYMKLTDIQHKYLDELSGGQRQRAYIAMVIAQDTEYILLD
                     EPLNNLDMNHSVQMMKVLRGLCDELDKTIVLVMHDINFASCYSDNIVALKNGKVEKVG
                     RTDEIVNEKVLEDIYEMNFNIKNINGNRICIYF"
     gene            18187..19152
                     /locus_tag="PC494_002703"
     CDS             18187..19152
                     /locus_tag="PC494_002703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HDF3913194.1"
                     /translation="MNKKAAIVAAVAIIGLVTVFALGGSKKNESKTSENSNNTMKITH
                     NLGETDVKLNPKKVVVFDYSALDTMDALGVAETLVGLPKASLPASLEKYKDDKYADLG
                     GLKEPDLEGIKSANPDLIIINGRQEDFYEQLSKIAPTISTSKDDKKYLESVKNNIDKI
                     AKIFGVEEKANQEFSKIEKKIETLNKKVTDKNLNALTIMVNEGNLSVFGEESRFSILY
                     NSFGFENKDKNIKESSHGQNITFEYIAKQNPEVMFVIDRGIATGSDVKESSTAKSVLN
                     NDIIKSMDAYKNDNIIYLDSPTWYVNDGGLTSLNKMIDDASKAVN"
BASE COUNT         7637 a         1966 c         3455 g         6260 t
ORIGIN      
        1 ggtagtagtg gcgaagacac cgtccgaagt agcttggctt tgtaaccacc tctgttgtac
       61 tgtttaagta taaataagtg tgttagccac caagaatccc cttgctttag ctatggggag
      121 tgtgtcaaat attaaacata gcttttatac atttaataag gtatgtaaaa tctatgtaaa
      181 aagtaagaaa tataaacatt tttttaatta tattttaaaa atatcaagca agttttcttc
      241 acaaatgaat aaaaaatgtt ataatatgat taaagaaaaa gataaataat tagcaagatt
      301 tgtttagcta aaattaacaa gggagcgata aattatgggt ataacattat caaaaggcca
      361 aaaggttgat ttaactaaag gaaatccagg tcttaaaaat attttagtag gtttaggatg
      421 ggatactaac aagtatgatg gtggatttga ctttgattta gatacagcag catttttaac
      481 aggagcaagt ggaagtgtta ctaatgatgg agattttgta ttttacaaca atttaaaaca
      541 tacatctgga gcagttgagc atctaggaga taacagaact ggcgaaggtg atggagatga
      601 tgaacaaata gttgttgatt tatctaagat tcctggagaa ataagcaaga tttcttttac
      661 tgttacaatt catgatgcaa cagaaagaag acaaaatttt ggacaagtaa gtaattctta
      721 tataagaata gtagataaag acacaaatga agagttaata aagtatgaat taggagaaga
      781 ttttagtata gaaacagcta tagtagtagc tgaaatatat aagcacaatg gagaatggaa
      841 gtttaatgca ctaggttctg gctttgaagg tggtcttgct gcattatgtg gaaactttgg
      901 aataaactta taatttcaac tataacaata aactaaaggg ggatattttc catggctata
      961 gtattaaaaa aaggacaaaa aatcgattta actaagggaa atccaggtct taaaaatata
     1021 aaacttggac taggatggga tacaaattca tttgatagtg gctatgatta tgatttagat
     1081 gtaagtgttt tcatggttgg agaatctcaa agagttgaaa aagatgaaga ttttatattc
     1141 tacaataact taaaacatcc atctggagca gttgaacact taggtgataa tagaactggt
     1201 gaaggtgatg gagatgatga ggaaatatta gtgaatttag agacaatgcc aaagcatata
     1261 caaaagatag ctgtaacagt tacaatatat gaggctgctg aaagaagaca aaattttgga
     1321 caagtaagta actcatatat aagagtatta aattctgaaa atgatgaaga aatattaaga
     1381 tatgacttag gtgaagaatt tagtatagaa actgcaatta cagtatgtga gatatataag
     1441 tataatggag aatggaagtt tagtgcagtt ggagcaggat ttgaaggtgg cttagaagca
     1501 ctttgtagaa actatggctt aaatgtttaa tttaagcaat ataatatatt aaatataaat
     1561 aacctataca aataatgtat aggttatatt atataaaatt ttgtggaggt ttagtatgtc
     1621 gattaattta tcaaaaggtg ataaaataga tttaaaaaaa tctaacccag gactgagtaa
     1681 catacttgta ggtctaggat gggaccctgt gcaacaatct ggtggaggtt tttttaaatc
     1741 gttatttggt ggaggacaag ctgatataga ttgtgatgca tctgtattta tgcttaatca
     1801 agaaggtaaa ttaagtggaa taaaagattt aatttatttt ggaaatctaa aaagtgcctg
     1861 taaatcagtt ttgcatacag gagacaatct aactggtgag ggtacaggtg atgatgaaca
     1921 aatcctagtt aatttggata aagttccatc aaatattcat aaattattgt ttgtagtaaa
     1981 tatatacaat tgtgtagata gaaaacaaca ctttggaatg atagaaaatg cctatataag
     2041 agttgaagac caaggtaata agaaagagat agcaaaatac aatctatctg ataattattc
     2101 tgaaaaaact actcttatag taggagctat atatagaaaa gatggaagtt ggcaatttaa
     2161 agcaattggt gaaggaacaa aagatgcggg tcttaaagaa gtaatgcaaa atttagacag
     2221 gattgagtgt gcatatggaa tttaataatg atatcaaata ttataatgta gataaagaag
     2281 aagttacaaa agacttatct gttaatcctg aaaaaggttt atcagaatca gaagtcaaga
     2341 ctagaagaga aaaatatggt ttgaatgaat ttactccaaa agaagagggt agtttttggg
     2401 atgatttaaa ggaaagttta agtgaaccaa tgatagttat cttgattatt gcagcagtag
     2461 taagtgcagt aattggggaa actcatgatg caatagggat tgtaggtgct atagcaatag
     2521 gtatagcaat aggtatgatt acagaaggtc gttctaagaa agcagcagag gctctttcta
     2581 agttgactga aaacatagaa gtaaaagtat tgagagatgg ggaagtacat caaatttcta
     2641 agagtgaatt ggtaccaggt gatatagtat atattgaaac tggtgacatg gtacctgctg
     2701 atggtagact tatagaaagt ataaacctta aaattagaga agatatgtta acaggagaat
     2761 ctgatgacgt atctaaaaag tgtgatgtag tagtttctat ggaagagata gaatctaaag
     2821 gagcagtagt agtacaggag ccaatacctg caaaacagat aaatatggtg tttggtggca
     2881 cacttgtagc ttatggtaga ggagctctag ttgtaacttc aattggagat aatagtgaaa
     2941 tgggtaaaat tgctcaaaac ttatcagaaa cagatgagca aactccactt cagataaaac
     3001 ttggaaattt aggtggtttg atagccaaag tttctagtgc agtagcagga ttactattta
     3061 tatttatggt tttccaaatg ataagtaaga atgtattaaa tgtagatatg tctggaatat
     3121 taccgttttt agaatcaata gacccagtta aaacagcatt tacagtatgt gttgcgttga
     3181 tagttgcagc agtgccagaa ggtcttccaa ctatgataaa tatgacactt gcaataacaa
     3241 tgcaaaaaat ggctaaaata aatgcattgg ttactaaaaa agaagcttgt gaaacgatag
     3301 gttctgtttc tgtaatatgt tcagataaaa ctggtacatt aactgaaaat agaatgactg
     3361 tagaagttgc atatgttgat ggcagatata ttgaaagttc agaagaggaa ataaatagtt
     3421 attttgaaga aaactgtatg ataaactcta cagctgatgt agagcacaat gatggtgata
     3481 ttaagtattt aggaagtgct actgaatgtg cattgctttt atattacaaa aacgtagatt
     3541 atagacaagt tagaaaaaat tctaatatag tagctcaaaa tccttttact tcagattcaa
     3601 agagaatgac ttctgttata ggtcaagata atcatcatgt actattatca aaaggagcac
     3661 cagaagtctt acttgaatta tgttcacata ttcaaagagg aaaagacata gttccattaa
     3721 ctgaaaatat aaaacatgag attttagaag aaataaagaa attgcaaata aaatcaatga
     3781 gaactttagg gtttgcatat aaagaaatct cacaagctga agaagaagca gcagtaactg
     3841 ctgaaagtga tgctatgaat gtaagtgcaa tggaaaacaa tttagtattt agtggttttg
     3901 ttggtataag agacccactt agaaaagatg ttatagagtc tgtaaataca gcaaataaag
     3961 ctggtgtttc tgtaaaaatg cttacaggag ataatataaa tacggcaaga gctataggtg
     4021 aagagttagg cctattaaaa aataatatga gagtggttga agcttcatat atagatactt
     4081 tagatgatga agaattaaaa caagagatac aaagtatttc aatcgtggca agaagtaaac
     4141 cagatagtaa aatgagaata gtttcagctc tgcaaaagag cggagatgtt gttgcagtaa
     4201 caggtgatgg tataaatgat gctccagcac tttcaaaagc agatgttggt atagcaatgg
     4261 gtatatctgg tacagaggta tctaaaaacg cagcagacat aattttaact gatgatagtt
     4321 ttagtaccat tgtaaaaggt attaaatggg gtagaggaat ttatgataac ttccaaagat
     4381 tcgttcaatt ccaattaact gtaaatgtaa ttgcattttt agtggctata atatctcaag
     4441 ttatgggaca agagatgcca tttactacaa tacaattatt atgggtaaac atcattatgg
     4501 atggaccacc agcactagca ttaggtttag agccagttag ggaccatgtg ttaaatagaa
     4561 aacctgttga tagaaaagcc aatataattt ctaagtcaat ggtgtataca atagtattaa
     4621 atgcatttta tataacagca atactaatgt tacaatctac atttaatttc ttaggagttg
     4681 atgaagcgca taagggaaca gtaatgtttg cgttatttgc ttttagtgca ctgtttaatg
     4741 catttaactg tagagagttt aatgcagata gtatcttccc taattttaca cataacaaat
     4801 tagcactaca aataatagtg ttgacaggaa ttgcacaagt aatatttact cagctattcc
     4861 aagatttctt taactctgta gcaatggatt ttatgacatg ggtaaaagtt ttatgtgtag
     4921 cagcaagtgt aattgtggtt aatgaagttg taaaatgtat aataagactg gtaaaactaa
     4981 aaaagactgc ttaaaacaaa ttttttagaa gaaaacagac tgactcaaaa tatgaatttt
     5041 gggtcagttc tgaataaaca tttaaattgg gaggatagtt atgggtgact caaaggtatt
     5101 tgaaaaaata ttctccagcc aatcagatag aggaaattac actccttcaa agggatatct
     5161 aagttatttt atttcgtata ttggtttaga agatgaagtt ttgtacaatc tcgagatatt
     5221 taagacaaaa caaaatattg atagcaaaaa agatattgct ttatttactg atgttatagc
     5281 aaatcctagt gattttgata ttataaatta ttttaaaagt ggacttcaaa aatatagaac
     5341 tagcatggaa gatgtagata taaatatttt gggatttgaa gagattgatt ataaaataaa
     5401 gcaagcaatg gatagagtgt taaaagaaga ggaaaaagaa tttactaatg atagagttaa
     5461 acaaaatttt atagtgaaaa taatggcatg gataaaaatt tatatcggtg ctttagatat
     5521 aaataaaaat gaagctccaa aagtaatatt ttatggagat ataaaaaaac atgaagttta
     5581 tttactctta atattatact tggcaggttt tgatgtttta tatcttaatc caaattcaaa
     5641 gagtaatata gatattttaa aatcagaaag atacaatata gagtttgaag aagccaacat
     5701 aatagaagaa aaaatttctt ttgaagaaag ggttatttta ggggaaaaaa tagataaaag
     5761 ttctgtaaaa aaagctttta ctgttggggc agaagcatca aagcgtataa gtgaggaatt
     5821 gttaaatgat gcaggattta taaaaccttg gcaactccaa gatagaaaaa taaaaaatct
     5881 acttctaagt tcaactgttg atgaaatatc aatatactgg aatcaaccac ttaaattaag
     5941 accaggattt aagtttaatg atgctattgt agaagctcca aattttcttt ctaagattaa
     6001 tggaatatat aacgataaga atgaatatat taagttttta gatttattaa gagattcgga
     6061 aagttcaaca tttattgaat ttaatggaga tgtagataga ttttcaaaag cttttacaag
     6121 agaagctttt agtttatcct ttttattgga ttcaaaaggt gcaatagata aaaactctgt
     6181 tttaaataat aaagattatt ccatatcaac actagcattg aatcaacaaa ttatgatttt
     6241 agagaaagtg gaagagttgt tagaaggaag tatgtttttg aatggtttaa gtggagaaga
     6301 caagataaaa ggtctattta cagtacttca catggataag aaatttgttc atatgatgaa
     6361 caatttcgat tactcactta taaacccaaa attgattata tacatgtaca agagtattgt
     6421 atttgataaa gaaatagttt ttcttatgct tttacttagt aagattggat ttgatattat
     6481 catattatgt ccaggaggag aaaacaatat agagaatgtt ataaataacc aattgattga
     6541 tgtacacaga ttggataaaa tggtatatga ccttaaatta aattcgcttg aaaatgatat
     6601 acctttactt aaaaaaattt ttggaaagag gagacgattt tagatgggga taaatataaa
     6661 tagtttttca aaagataaga actctgtaga ggttactgaa aatttgccta cagcagttca
     6721 agaagaaaac ttcgatataa tggaatatac aaataataaa aaaaatgaac tgagaaagtc
     6781 taaggaagtt gaggcattga catctcttat agaagtagaa aatccagata cgattttaca
     6841 gtttggtagg aaagcatctg aaggagtagc aagagtttct gatagccttt taaatacaat
     6901 aaaattaaat agaaatgaag aaaattctaa aatgttggtt catttaacta aaataatgga
     6961 caagtttgat ttagacgatt ttcaagaaac taaggaacca aatttcgttc aaaaactttt
     7021 caaaaaagct aataatgcca ttgaaatgat gtttcaaaag tatgaaacat tgggaggaga
     7081 agttgagaaa attcaaattg agcttgaaca atacgaaaga gatatagcac tttctaataa
     7141 gcaaataggt gctatgttaa atgaaaactt tgagttttac aatgaacttc aaaaatatat
     7201 tgttgctgga gaaatggcaa tagaagaaat ggataatgaa atactacctt tctttaaaca
     7261 aaaatcagag actagtggag accaaatgga tgttgtcaat tatcaagaac tattaaaagt
     7321 ttatgatatg ttaaatcaaa gagtctatga tttaaggata gcagaaaata tagctatcca
     7381 aacaatacct atgcttagag gtatgcaaca taataattat ggtttaatta gaaaaataaa
     7441 tagtgcattt gtcgtaactt taccagtatt taaacaatgt ttatctcaag ctatattact
     7501 taaaaagcaa gaattacaag caaaatctct aaaagcactt gatgacaaaa ctaatgaatt
     7561 attgcttaga aatgcacaaa atgtaagtac tcaaagtgca caaatagcta gaatggctgg
     7621 aacaagttct gttcaaatag aaacattgga aaaaatgtac aatactatca agtctggtat
     7681 agatgaaact atgagaatag aagaaaacaa tagagcttta attaaggata atacaaagag
     7741 attggaagaa ttaaatacga ctataattta taataagtag tattatatta agggctaatt
     7801 tgtataaagt tggccctttc tatgtatatg aggaggctag acattgaaat atttcgatta
     7861 tatctgcaaa gatgatttgg agagaatttt tttgaaggag ccagaagatt ttagtgctaa
     7921 gactgaaaaa gatgtgttga aatatgcact gggcgctttt ttatacgttc cagctactca
     7981 atataatatg atttataaga gtattatagg ggatgttaag ggagttagac cattagctat
     8041 ttgtttagaa gatgctgttg gagtaaatgg agagttggag gctatagaaa atcttagatt
     8101 aattttaaaa aatattagca atgaaagtat aactaataaa gatggaatac cactaatttt
     8161 tgtaagaata aaagatgtgg agcaactgtt gagaattaaa gagattataa ttaaaaatag
     8221 tcattttata acaggaatat taattcctaa agcaaattcg gagttaattg aaaattgtat
     8281 agaagcttta gattttatga atcttcaaga tatgtatgtt attccgatag tagagacaaa
     8341 agaatttata tataatgaaa aaaaagaact tagttttact aatttgtaca atgctatttt
     8401 aagacataag tcaagaatat taagcattag agtaggcata actgatatat tagggatgta
     8461 tggtataagg agagataaaa acttttctat atataataat ttgatttgtt cttcatttat
     8521 attagatata atcacatatc ttcaaagacc agagttagat atacctataa gtggtggagt
     8581 atcagaattt tttgatatga cgaataagga tataagaaat aagtatatag aagaaatatt
     8641 attggataaa tatcatggat taattggaaa gaccgtaatt catccaatgc aaattcaaat
     8701 tgtacaagcg ctatctacag tatcatatga agattttact gatgctttgg atatactgga
     8761 tagtacagac agtaagtatg gtgtgagcaa gggtgtatta ggagagagaa tgaatgaaac
     8821 aaatccacat tttttatggg ctaaaaaaac attgattcta tctaaaatat atggtgtatt
     8881 aaataaagga gtagactatg aagaattgct taaattttaa ttgtgagatt gacattattg
     8941 ataatccatt gaatttagaa ctaaatgatt ttttagacgt aggaataaga aataatagca
     9001 aaagacgttt tttgtttatc tcaaagaaac tcggtaaaca tttagcatgt aagccaagtg
     9061 agatggataa tttgggaaaa ttaatggcta caatttataa tgaaaaaaat aaggaagaat
     9121 caaatggtac tgttatagct tttgctgaaa ctggtacagc tgttgggcat agtttttttg
     9181 attacttatg tggagattat gaatttattc atactactag agagcagttt gacgagttag
     9241 aaaatctgga atttttagag gaacattccc atgcaacaga ccagaattta tactttggta
     9301 tgcttaacaa ctttaaattt ggagatgaga taatattggt tgatgatgag attaccacag
     9361 ccaatacatg catgaatata attaggaaaa ttcaaagcat ttatcctaaa aagaaataca
     9421 ctatatgctc aatactcaat tgggtaagtg atgaaaattt aagtaaagtt actcgtttag
     9481 aaagagagct agattgtaag atagattttg tatacttatt taaaggaaac tttaaatttt
     9541 atatagatga agatattatt tcaaattaca acgataatta tagtattact aaattagaga
     9601 ctatttcaag tgataaagta aatttagtag taaatcatat ttatgttgat ttagaagatt
     9661 atattggaaa taagaaatat gtaaaatata caggaagatt tggaattaat agaagagaac
     9721 aatttagatt aaaagaaatc gttaagagag aaagtaaaaa aataactatg gccagtaaag
     9781 aatctttaaa aaatgaaaaa gaaaagattc tatttttagg tactgaagaa tttatgtata
     9841 tacctatgct gtttgcaaaa gaaaaagaaa atcaatatga tatatactat cattcaacaa
     9901 caagaagtcc aattattaat attgataaga ataattatcc tattaaaagt aaatttatgc
     9961 taaagagttt ttataatata gatattcaaa attatattta caatatagat aaacataatt
    10021 tttctaagtg ttatttattt gtagagctga ataaaagtga aaattcttat ctagaattta
    10081 ttgatataat taaaaaaaca agtataaaag aattaactat agtatgttgt agctaaagtg
    10141 ttttaacagg ataaaatata tcacgatttt aagataggag ttgagtcata tgagagattt
    10201 tagcacgtat tctaaagatg atgttatttt tttattaaaa gatatatcaa atttaattga
    10261 agaagaagga aataaagaaa gagaattaaa aatacaaaat ggtagacatt attcagaaat
    10321 gataccaata gagtatgaag ttagtgaaga ttatctgaat ttatatcatg agaaactaag
    10381 agaaaataaa gataaacttg cattttctat aggagttatg tgtgaaaaaa taattaaaaa
    10441 aaatggaaat gatgtagtac tagtttcact tgctagagca ggaacaccta ttggtatttt
    10501 ggcaaaaaga tatataagaa gcaagtataa tataagttta cctcactata caatctctat
    10561 aataagagat aagggaatag atatgaatgc aattgaatat atagtaaaga atcatccgag
    10621 ctcaaaaatt caatttttag atggatggac tggtaaggga actatatcaa aagaacttga
    10681 aaaagcatgt gatgaactta atgttaaatt taaaaaatat tttgactcaa cacttgctgt
    10741 attagctgac cctgctggat attcaggact ttatggaatt agagaagatt tcttaatacc
    10801 aagtgcatgt ttaaattcaa cagtttctgg tttagtaagt agaactgtac taagagagga
    10861 tttaattggt aaaaatgact tccatggagc taagttttat agacatttaa aagataaaga
    10921 tgaatctatg aactatatcg aaactataga agaatgtttt aaaaatcaat ttaagaatat
    10981 atctgatgaa gttgaaaact gggaaagtga cattataaca agagatggat actttgatgt
    11041 tttaaatata aaagaaaagt ataacataac agatattaac tttatcaaac caggtgtagg
    11101 ggaaacgaca agggttttac ttagaagagt tccgtataag attcttgtta aagacttaaa
    11161 tgataaatct ttagaccata tattcatatt agctaaggag aaaaatgttg aagttgaaca
    11221 aatggattta aaagcctata aatgttgtgg aataataaaa aatatgaaag atatttagga
    11281 aatatattag acaggagaat attgaatgat tgttttttca gatttagaca ggagtatcat
    11341 ttactccaat aaatttttaa atgctgatag taaatatact aatatagaaa tttataggga
    11401 aaaagaaata tcttatatat ctttagatac tataaattta ataaagcaaa tacaatatta
    11461 tggtatgttt atacctacaa ctactagaac agtggagcaa tttaagcgta tagaatttaa
    11521 taaatatggg atttattttc cttggagtat aacttcaaat ggaggagtta tacttaaaga
    11581 taatgaaata ttgaaatcat ggagtgaaaa aatagataaa ctaaaatgtg attatgagcc
    11641 cattgaaagt atgattcata aatttaaaga ctatttgaat gtagatggaa taactaattt
    11701 taaagttgca gaagatacat ttttttatat agttgttgat ttatcaagat ttaatttgga
    11761 ttcaatcaaa gaatatacaa atatattgga atcaaaaaat tggaagtttt atgtgagtgg
    11821 cagaaaaata tattttatac caaaagaaat ttcaaaagaa aatgctataa aatacttgac
    11881 taaagaatta ggaatagaat atttttatgc agttggagat tctattatgg actatggtat
    11941 gcttaatatc tcaaataaat cctatgtatt gaagcatggt gatataaata aaaatgaaat
    12001 agaaaattca tttatatcaa gttctttcaa tggaatgagt ggaactgaag agatactatc
    12061 taacatttta gacgagaact gcctacttaa tatataatga ctgatatata aataataaac
    12121 tagaaaaatc tgaaataaat tatagtaaag tttatcatac taatttattt cagattttta
    12181 tcaatttata tttaagtaag aactcaatat gttaaaatga aggtggagtc attgcccaga
    12241 ctgagataca tacctcatca tcataatttt catacacatg tggtatagta ctgttaaaat
    12301 aaaaactatc tccttcctcc aatagatatt ccttatttcc aagtgttatc ttcattttac
    12361 cttttattat atagccacat tcttctcctt cgtgtgtcac aaattcactg tttttttgtg
    12421 tatgaccatc tagtgtaaca agtataaatt ctattttttt cccagataaa ttaggaacaa
    12481 gaagttcata aaattttgta gaatcattag ttactatttt ttttcgatta tttttcttta
    12541 ctactatatc agagtcttct cttccaatct cttcaaaaaa ataacctata tttatatcaa
    12601 gagcttttga tattttccac attgctacaa tagatggaac aaccatatta cgctcaattt
    12661 gacttattaa gcctgtactt aaatctgaat tttttgctaa agtagagata cttatatttt
    12721 tagattttct aagagatcta attttgcttc caacatctat attcattaga tacaaacccc
    12781 ctcagacatg attataacat ataatttata aagattaata aaataaaaaa aaagttttac
    12841 aatacaagta ttttttatgc tatattgaat tttctgaaaa gatgcattat aatagtatta
    12901 atattcaata tattgaatat tgataacgat attttaattt aatgaaatgg aggtaattaa
    12961 gatgaagagt tttgtaagtc ctgataatat ttgggtatta tgggcagttg taactggatg
    13021 ggcagcattt agtatttatt tggaacaaaa gtacaattgg gcatcaaaag tgtcgggagc
    13081 aataatagct cttgtaggag caatgttatt atcaaatcta aatattatac cagtagagtc
    13141 tgttgtatat gaccaagtat ggggatatgt tgttccttta gccatagctt tattgttata
    13201 tcaatgtaac attaaaaaga tatggaaaga aagtggaaga ttgctcatta tatttcttgt
    13261 aggttctgta ggaactgtac ttggagctat gattggattt ttagcattaa aaaatgtagt
    13321 accagattta aatattgttg cagctatgat gacaggttct tatataggtg gaaatgtaaa
    13381 ctttgctgct atgtcagggg cgtttgatgc gccaggagaa ttagtatcag caacagttgt
    13441 agcagataat cttttaatgg cattatattt ctttgtctta atagctatac catcaattgg
    13501 attttttaga aaacatttta aacatccaca tgtagatgaa atggaaagta taggtataac
    13561 tgaaggagaa acagtagcag caaattattg gggaagaaaa gaaatatctt taaaagatat
    13621 agcaatagcc attggtagcg cctttataat tgttgcagta tctgtagaac tatcaacttg
    13681 gtttaaagct ataataccat tatcaaatcc ttttttagca atgttaaata ctttatttgg
    13741 aaatcaatat ctaataataa ctactttgac tatgttgttt gccacattta tgcctaattt
    13801 ctttggtgat ataaaaggag cacaggaatt gggtacattt ttaatatata tattctttgt
    13861 tgtagtaggt gttcctgctt caataacatt aataattcaa aaatcaccat tactactttt
    13921 atactgcgga ataatggtac taataaacat gctagttaca tttatagttg caaaaatatt
    13981 taagtttagt ttagaagaag ctattcttgc atctaatgca aatattggtg gtcctacaac
    14041 agcagcagct atggcaatat caaaaggatg gtctaagcta gtagggccaa tacttatagt
    14101 tggaacattt ggatacatag tcggtaatta ttttggtctt ttagtaggaa atattttgat
    14161 ataattttac gtgaaaaaaa gttgtttatt agaaagattt ttatttaatt ggaggttgtt
    14221 atgattttcg atggacattc agatacttgg gcagatgtaa caataagaag gcttaacggg
    14281 gaaaaagatg tatttagaag aatccatctt gataatttta aaagagcaaa tatagaagga
    14341 gctatttttg taatatggat agacccacca tatgataaag agcctgaaaa aagagttaaa
    14401 caaattataa gttctataaa agatgaaatt gaagatatga aagatgttgt aaacatagta
    14461 aaaaaatatt cagatataga taaaggtata agtgaaaaca aaataaatat tttaattggt
    14521 cttgaaggat taagccatat tggaagaaat atagatttac tagattattt ttataaagaa
    14581 gttggtgcaa gacatgcatc attaacttgg aatgaacaga atgaacttgc tacaggatgt
    14641 ttaggggatg aaaatcgtgg tttaagtgaa ataggcaaaa aagcagtcaa taaaatggaa
    14701 aaattgggca tgatagtaga tgtgtcacat ttaaatgaaa aatcattttg ggatttaatg
    14761 tctgttgcaa gtaagccagt tatagcttct cattctaatg ctaggagttt atgtgatgct
    14821 aaaagaaatc ttacagataa tcaattaaaa gaaatttcaa atacaggtgg attagttgga
    14881 ataaatagtt ttagaggatt tactaatagt aatcctaaga agcaagattt aatacatttg
    14941 gttgaccata tagactatat ggtaaatctt ataggtatag aacatgtatc ttttggtttt
    15001 gattttagtg attacttagg gaaagagact ataggttctt ttactggaaa tgctagtgtg
    15061 ccaagtgtag atggtcttga aagcacacat acagcacaga acatagtagt agagcttgaa
    15121 aatagaggtt ataaaaagaa agatatagag ttaatctcta gtggtaattt ttataggctc
    15181 tttaaagata tactaaaata atataataaa gaacttaaat ttataaaata gtatatttat
    15241 acaaataata tctacatatt taaattggcg ttcataattt attaaatttt aatgttacta
    15301 gaagtttcaa ttctagtaac attttttatg ttaaaaacag atatagatat gtattgacaa
    15361 tgataattat tattgataaa ctataaaagt gaaaatgata ataattttca ttttaattaa
    15421 taaaagattt ttaaggaggg agaatgaaga aaaggtattt agtcatagga ataataattt
    15481 tgtcttattt ttctttattt ataggagctg aagatataaa tataatgcat atatttgcca
    15541 aaaatcagca taaacttatg atatttatca tgagtagaat accaagatta ataagtatat
    15601 tgattgctgg tgtaggaatg agcatagcag gtcttataat gcaacagata agtaagaata
    15661 aatttgtatc acctacaaca ggtgctacaa tagatgcagc acaatttggg atagtaatat
    15721 gtatgctttt agtaccaact gcctctattt ttacaaagac aataatagca tttgtatttt
    15781 ctcttgtagg gacttttacg tttatgaaaa taatagggaa gttacaattt aaaaatataa
    15841 tctttgtacc attagtaggt ataatgtttg gaaatataat agggtctatg acggatttta
    15901 tcgcgtataa atacgatttg agtcaaaatg ttagttcttg gatgcaaggt gacttttcta
    15961 tgatacttaa aggaaattat gagatattat atatcacaat accccttata atattagcat
    16021 atatttatgc aaataaattt actgttgttg gtatgggtat ggattttgcg acaaacttag
    16081 gtcttagtta caaaagaatt gtcaatatag gtctgataat agtagcactt gttacagtat
    16141 gtgtagtcgt tacagctggt aatatccctt ttataggtct aatagttcca aatatcgtat
    16201 ccttgtacat gggtgataat ataagagcaa gcatatggta tactggttta cttggagcga
    16261 tatttgtact tatatgtgat atttttggaa gaattattat ttatccatat gaaatatcta
    16321 tagggcttac agttggagtt ataggaagta tactattcct ttatttaata ttaaggagga
    16381 atgtgaatga agcttagtct caatcaaaaa atttactttg taagtatatt actattcata
    16441 tcaatggcac tttttataat ttatggaata gacatgaatc atttagaata tgcattatca
    16501 caaagaatac caaaaatatt tgctatggta ttaggtggag gatgtatagc atttactact
    16561 gtagtgtttc aaacaattac aaacaatcaa atattaacac caagtgtact aggtttagat
    16621 tcattgtatg taatgattca aactataata gtattcatat ttggttcaag cagtagtctg
    16681 attataaatg aaaattataa ttttattatt aatgtagcta tgatgattgg agcttcattg
    16741 ttattatata agacgttatt tgaaaaaaat aaaaataata ttttcttttt aatcctagta
    16801 ggaatgatat ttggaacctt atttaaaagt gcaacaacat ttattcaggt aatgatagac
    16861 cctaatgaat ttttagcttt acaaactagt ataatggcaa gtttaaacaa tataaacact
    16921 aatgtattgt taatagcatt tataataatt attgccataa taccttttat atatgatgaa
    16981 ataaagtatt tagatgtatt gtcgttaggt aaagaacaag caattaattt aggtgtagat
    17041 tttgataaag cagttaaaaa aatgataata ttaatagcaa ttttagtctc aatatcaaca
    17101 gcacttattg gacctatgac atttttagga cttttacttg ctaatataac aagagaaatt
    17161 tttaaaacat ataagcatac atacttgatt tcgggttcta tgttgatagg gatgattaca
    17221 ttgataatag gtcaattttt tatacaacat gtatttaagt ttgatacaac tttaagtgta
    17281 gtaataaatt ttataggagg aatttatttt attcaattac tattaaaggg ggcaaataga
    17341 tgatagagat aaaaaatata tttaaaagat ataagaataa aaatgttgta gatgatgtct
    17401 cttttagtat agaaaaggga aagataacat cttttatagg accaaatgga gctggaaaaa
    17461 gtacagtact atcaatagtt acaagactta taggaggtga tggtggagaa gtaataatag
    17521 aaggaaaaag cttgactaat tatagcaata aagaattagc aaaaaaaata gctattctta
    17581 aacaatctaa caatataact ttaaagctta caataagaga attagttgga tttggaagat
    17641 ttccatatag tgaaggtaat ctaactaaag aggatgaaaa ttatattgat gaagcaatag
    17701 aatatatgaa gttgactgat atacaacata agtatttaga tgaattgagt ggaggtcaaa
    17761 gacaaagagc ttatatagca atggtaatag ctcaagatac agagtacata ttacttgatg
    17821 aaccactgaa caatttggat atgaaccatt ccgtacagat gatgaaggta cttagaggtc
    17881 tttgtgatga attagataag actatagtat tagtaatgca tgatataaat tttgcatcat
    17941 gttattcaga taatatagtt gcattaaaaa atggaaaagt tgaaaaagta ggtcgtacag
    18001 atgagatagt aaatgaaaaa gttttagaag atatttatga gatgaatttt aacattaaga
    18061 atataaatgg aaatcgaatc tgtatttatt tttaaaatat tgtatatgaa aataaacttg
    18121 ctatatgatt ttttataaag tttttaaatt aaaataaaga ttaataggag agaggaaaat
    18181 attgatatga ataaaaaagc agcaatagta gcagcagtag ctattatagg attagtgaca
    18241 gtgtttgcat taggtggaag taaaaagaat gaatcaaaaa catcagaaaa ttcaaataat
    18301 actatgaaga taactcataa cttgggagaa acagatgtaa aattaaatcc taaaaaagta
    18361 gtggtatttg attattcggc tttagataca atggatgcat taggtgtagc tgagacttta
    18421 gtaggacttc caaaagcgag tttaccagca tccttagaaa aatataagga tgacaagtat
    18481 gcagatttag gaggattaaa agaaccagat ttagaaggta taaagtcggc aaatccagat
    18541 ttaattataa taaatggaag acaagaagat ttttatgagc aattgtcaaa aatagcacca
    18601 acaataagta caagtaaaga tgataagaag tacttagaat ctgttaaaaa taatatagac
    18661 aaaatagcaa aaatatttgg agtagaagaa aaagcaaatc aagaatttag taaaattgaa
    18721 aagaaaatag aaactttgaa taaaaaagta acagataaaa atttaaatgc tttaactata
    18781 atggtaaatg aaggtaattt aagtgtattt ggtgaagaat caagatttag tatattatac
    18841 aatagttttg gatttgaaaa taaagataaa aatataaaag aatcaagtca tggacaaaat
    18901 attacttttg aatatatagc taaacaaaat ccagaagtta tgttcgttat agatagagga
    18961 atagctactg gcagtgatgt aaaagaaagc tcaactgcaa aatctgtttt gaacaatgat
    19021 ataataaaat ctatggatgc atataagaat gataatataa tatatttaga ttcaccaaca
    19081 tggtatgtaa atgatggtgg tctaacatct ttaaataaaa tgatagatga tgcttcaaaa
    19141 gcggtaaatt aataatccga tataaccaaa atgtattttt tataaaatga ttatcaaata
    19201 aactaggagt ttttaagaac tcctagttta ttttttgcat aaaaaagata tagtttaaac
    19261 aataatatta tctataataa gataaatcta ttcaaaatct aataaaatat gaagttat
//
LOCUS       DAMKNB010000068        18841 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.070, whole genome shotgun sequence.
ACCESSION   DAMKNB010000068 DAMKNB010000000
VERSION     DAMKNB010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 18841)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18841)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18841
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.070"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            133..687
                     /gene="tcdR"
                     /locus_tag="PC494_002704"
     CDS             133..687
                     /gene="tcdR"
                     /locus_tag="PC494_002704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosylating toxin sigma factor TcdR"
                     /protein_id="HDF3913195.1"
                     /translation="MQKSFYELIVLARNNSVDDLQEILFMFKPLVKKLSRVLHYEEGE
                     TDLIIFFIELIKNIKLSSFSEKSDAIIVKYIHKSLLNKTFELSRRYSKMKFNFVEFDE
                     NILNMKNNYQSKSVFEEDICFFEYILKELSGIQRKVIFYKYLKGYSDREISVKLKISR
                     QAVNKAKNRAFKKIKKDYENYFNL"
     gene            1005..8105
                     /gene="tcdB"
                     /locus_tag="PC494_002705"
                     /gene_synonym="toxB"
     CDS             1005..8105
                     /gene="tcdB"
                     /locus_tag="PC494_002705"
                     /gene_synonym="toxB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_074049122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosylating toxin TcdB"
                     /protein_id="HDF3913196.1"
                     /translation="MSLVNRKQLEKMANVRFRTQEDEYVAILDALEEYHNMSENTVVE
                     KYLKLKDINSLTDIYIDTYKKSGRNKALKKFKEYLVTEVLELKNNNLTPVEKNLHFVW
                     IGGQINDTAINYINQWKDVNSDYNVNVFYDSNAFLINTLKKTVVESAINDTLESFREN
                     LNDPRFDYNKFFRKRMEIIYDKQKNFINYYKAQREENPELIIDDIVKTYLSNEYSKEI
                     DELNTYIEESLNKITQNSGNDVRNFEEFKNGESFNLYEQELVERWNLAAASDILRISA
                     LKEIGGMYLDVDMLPGIQPDLFESIEKPSSVTVDFWEMTKLEAIMKYKEYIPEYTSEH
                     FDMLDEEVQSSFESVLASKSDKSEIFSSLGDMEASPLEVKIAFNSKGIINQGLISVKD
                     SYCSNLIVKQIENRYKILNNSLNPAISEDNDFNTTTNTFIDSIMAEANADNGRFMMEL
                     GKYLRVGFFPDVKTTINLSGPEAYAAAYQDLLMFKEGSMNIHLIEADLRNFEISKTNI
                     SQSTEQEMASLWSFDDARAKAQFEEYKRNYFEGSLGEDDNLDFSQNIVVDKEYLLEKI
                     SSLARSSERGYIHYIVQLQGDKISYEAACNLFAKTPYDSVLFQKNIEDSEIAYYYNPG
                     DGEIQEIDKYKIPSIISDRPKIKLTFIGHGKDEFNTDIFAGFDVDSLSTEIEAAIDLA
                     KEDISPKSIEINLLGCNMFSYSINVEETYPGKLLLKVKDKISELMPSISQDSIIVSAN
                     QYEVRINSEGRRELLDHSGEWINKEESIIKDISSKEYISFNPKENKITVKSKNLPELS
                     TLLQEIRNNSNSSDIELEEKVMLTECEINVISNIDTQIVEERIEEAKNLTSDSINYIK
                     DEFKLIESISDALCDLKQQNELEDSHFISFEDISETDEGFSIRFINKETGESIFVETE
                     KTIFSEYANHITEEISKIKGTIFDTVNGKLVKKVNLDTTHEVNTLNAAFFIQSLIEYN
                     SSKESLSNLSVAMKVQVYAQLFSTGLNTITDAAKVVELVSTALDETIDLLPTLSEGLP
                     IIATIIDGVSLGAAIKELSETSDPLLRQEIEAKIGIMAVNLTTATTAIITSSLGIASG
                     FSILLVPLAGISAGIPSLVNNELVLRDKATKVVDYFKHVSLVETEGVFTLLDDKIMMP
                     QDDLVISEIDFNNNSIVLGKCEIWRMEGGSGHTVTDDIDHFFSAPSITYREPHLSIYD
                     VLEVQKEELDLSKDLMVLPNAPNRVFAWETGWTPGLRSLENDGTKLLDRIRDNYEGEF
                     YWRYFAFIADALITTLKPRYEDTNIRINLDSNTRSFIVPIITTEYIREKLSYSFYGSG
                     GTYALSLSQYNMGINIELSESDVWIIDVDNVVRDVTIESDKIKKGDLIEGILSTLSIE
                     ENKIILNSHEINFSGEVNGSNGFVSLTFSILEGINAIIEVDLLSKSYKLLISGELKIL
                     MLNSNHIQQKIDYIGFNSELQKNIPYSFVDSEGKENGFINGSTKEGLFVSELPDVVLI
                     SKVYMDDSKPSFGYYSNNLKDVKVITKDNVNILTGYYLKDDIKISLSLTLQDEKTIKL
                     NSVHLDESGVAEILKFMNRKGNTNTSDSLMSFLESMNIKSIFVNFLQSNIKFILDANF
                     IISGTTSIGQFEFICDENDNIQPYFIKFNTLETNYTLYVGNRQNMIVEPNYDLDDSGD
                     ISSTVINFSQKYLYGIDSCVNKVVISPNIYTDEINITPVYETNNTYPEFIVLDANYIN
                     EKINVNINDLSIRYVWSNDGNDFILMSTSEENKVSQVKIRFVNVFKDKTLANKLSFNF
                     SDKQDVPVSEIILSFTPSYYEDGLIGYDLGLVSLYNEKFYINNFGMMLSGLIYINDSL
                     YYFKPPVNNLITGFVTVGDDKYYFNPINGGAASIGETIIDDKNYYFNQSGVLQTGVFS
                     TEDGFKYFAPANTLDENLEGEAIDFTGKLIIDENIYYFDDNYRGAVEWKELDGEMHYF
                     SPETGKAFKGLNQIGDDKYYFNSDGVMQKGFVSINDNKHYFDDSGVMKVGYTEIDGKH
                     FYFAENGEMQIGVFNTEDGFKYFAHHNEDLGNEEGEEISYSGILNFNNKIYYFDDSFT
                     AVVGWKDLEDGSKYYFDEDTAEAYIGLSLINDGQYYFNDDGIMQVGFVTINDKVFYFS
                     DSGIIESGVQNIDDNYFYIDDNGIVQIGVFDTSDGYKYFAPANTVNDNIYGQAVEYSG
                     LVRVGEDVYYFGETYTIETGWIYDMENESDKYYFNPETKKACKGINLIDDIKYYFDEK
                     GIMRTGLISFENNNYYFNENGEMQFGYINIEDKMFYFGEDGVMQIGVFNTPDGFKYFA
                     HQNTLDENFEGESINYTGWLDLDEKRYYFTDEYIAATGSVIIDGEEYYFDPDTAQLVI
                     SE"
     gene            8227..8727
                     /gene="tcdE"
                     /locus_tag="PC494_002706"
     CDS             8227..8727
                     /gene="tcdE"
                     /locus_tag="PC494_002706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holin-like glycosylating toxin export protein
                     TcdE"
                     /protein_id="HDF3913197.1"
                     /translation="MHSSSPFYISNGNKIFFYINLGGVMNMTISFLSEHIFIKLVILT
                     ISFDTLLGCLSAIKSRKFNSSFGIDGGIRKVAMIACIFFLSVVDILTKFNFLFMLPQD
                     CINFLRLKHLGISEFFSILFILYESVSILKNMCLCGLPVPKRLKEKIAILLDAMTDEM
                     NAKDEK"
     gene            8806..8967
                     /locus_tag="PC494_002707"
     CDS             8806..8967
                     /locus_tag="PC494_002707"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3913198.1"
                     /translation="MKLIMKTREQMPRDTQVLNTYNFEASVHYYIDDKVVYQTLVHKD
                     GAWSVGKIY"
     gene            9056..9238
                     /locus_tag="PC494_002708"
     CDS             9056..9238
                     /locus_tag="PC494_002708"
                     /inference="COORDINATES: protein motif:HMM:NF022413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3913199.1"
                     /translation="MRDEGQNDIENKYQTLINDLIDSLKVIGKIYKEIKTLKKYKICL
                     QITIRQSPYLIEESIN"
     gene            9455..17587
                     /gene="tcdA"
                     /locus_tag="PC494_002709"
                     /gene_synonym="toxA"
     CDS             9455..17587
                     /gene="tcdA"
                     /locus_tag="PC494_002709"
                     /gene_synonym="toxA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_105161403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosylating toxin TcdA"
                     /protein_id="HDF3913200.1"
                     /translation="MSLISKEELIKLAYSIRPRENEYKTILTNLDEYNKLTTNNNENK
                     YLQLKKLNESIDVFMNKYKTSSRNRALSNLKKDILKEVILIKNSNTSPVEKNLHFVWI
                     GGEVSDIALEYIKQWADINAEYNIKLWYDSEAFLVNTLKKAIVESSTTEALQLLEEEI
                     QNPQFDNMKFYKKRMEFIYDRQKRFINYYKSQINKPTVPTIDDIIKSHLVSEYNRDET
                     VLESYRTNSLRKINSNHGIDIRANSLFTEQELLNIYSQELLNRGNLAAASDIVRLLAL
                     KNFGGVYLDVDMLPGIHSDLFKTISRPSSIGLDRWEMIKLEAIMKYKKYINNYTSENF
                     DKLDQQLKDNFKLIIESKSEKSEIFSKLENLNVSDLEIKIAFALGSVINQALISKQGS
                     YLTNLVIEQVKNRYQFLNQHLNPAIESDNNFTDTTKIFHDSLFNSATAENSMFLTKIA
                     PYLQVGFMPEARSTISLSGPGAYASAYYDFINLQENTIEKTLKASDLIEFKFPENNLS
                     QLTEQEINSLWSFDQASAKYQFEKYVRDYTGGSLSEDNGVDFNKNTALDKNYLLNNKI
                     PSNNVEEAGSKNYVHYIIQLQGDDISYEATCNLFSKNPKNSIIIQRNMNESAKSYFLS
                     DDGESILELNKYRIPERLKNKEKVKVTFIGHGKDEFNTSEFARLSVDSLSNEISSFLD
                     TIKLDISPKNVEVNLLGCNMFSYDFNVEETYPGKLLLSIMDKITSTLPDVNKNSITIG
                     ANQYEVRINSEGRKELLAHSGKWINKEEAIMSDLSSKEYIFFDSIDNKLKAKSKNIPG
                     LASISEDIKTLLLDASVSPDTKFILNNLKLNIESSIGDYIYYEKLEPVKNIIHNSIDD
                     LIDEFNLLENVSDELYELKKLNNLDEKYLISFEDISKNNSTYSVRFINKSNGESVYVE
                     TEKEIFSKYSEHITKEISTIKNSIITDVNGNLLDNIQLDHTSQVNTLNAAFFIQSLID
                     YSSNKDVLNDLSTSVKVQLYAQLFSTGLNTIYDSIQLVNLISNAVNDTINVLPTITEG
                     IPIVSTILDGINLGAAIKELLDEHDPLLKKELEAKVGVLAINMSLSIAATVASIVGIG
                     AEVTIFLLPIAGISAGIPSLVNNELILHDKATSVVNYFNHLSESKKYGPLKTEDDKIL
                     VPIDDLVISEIDFNNNSIKLGTCNILAMEGGSGHTVTGNIDHFFSSPSISSHIPSLSI
                     YSAIGIETENLDFSKKIMMLPNAPSRVFWWETGAVPGLRSLENDGTRLLDSIRDLYPG
                     KFYWRFYAFFDYAITTLKPVYEDTNIKIKLDKDTRNFIMPTITTNEIRNKLSYSFDGA
                     GGTYSLLLSSYPISTNINLSKDDLWIFNIDNEVREISIENGTIKKGKLIKDVLSKIDI
                     NKNKLIIGNQTIDFSGDIDNKDRYIFLTCELDDKISLIIEINLVAKSYSLLLSGDKNY
                     LISNLSNTIEKINTLGLDSKNIAYNYTDESNNKYFGAISKTSQKSIIHYKKDSKNILE
                     FYNDSTLEFNSKDFIAEDINVFMKDDINTITGKYYVDNNTDKSIDFSISLVSKNQVKV
                     NGLYLNESVYSSYLDFVKNSDGHHNTSNFMNLFLDNISFWKLFGFENINFVIDKYFTL
                     VGKTNLGYVEFICDNNKNIDIYFGEWKTSSSKSTIFSGNGRNVVVEPIYNPDTGEDIS
                     TSLDFSYEPLYGIDRYINKVLIAPDLYTSLININTNYYSNEYYPEIIVLNPNTFHKKV
                     NINLDSSSFEYKWSTEGSDFILVRYLEESNKKILQKIRIKGILSNTQSFNKMSIDFKD
                     IKKLSLGYIMSNFKSFNSENELDRDHLGFKIIDNKTYYYDEDSKLVKGLININNSLFY
                     FDPIEFNLVTGWQTINGKKYYFDINTGAALTSYKIINGKHFYFNNDGVMQLGVFKGPD
                     GFEYFAPANTQNNNIEGQAIVYQSKFLTLNGKKYYFDNDSKAVTGWRIINNEKYYFNP
                     NNAIAAVGLQVIDNNKYYFNPDTAIISKGWQTVNGSRYYFDTDTAIAFNGYKTIDGKH
                     FYFDSDCVVKIGVFSTSNGFEYFAPANTYNNNIEGQAIVYQSKFLTLNGKKYYFDNNS
                     KAVTGWQTIDSKKYYFNTNTAEAATGWQTIDGKKYYFNTNTAEAATGWQTIDGKKYYF
                     NTNTAIASTGYTIINGKHFYFNTDGIMQIGVFKGPNGFEYFAPANTDANNIEGQAILY
                     QNEFLTLNGKKYYFGSDSKAVTGWRIINNKKYYFNPNNAIAAIHLCTINNDKYYFSYD
                     GILQNGYITIERNNFYFDANNESKMVTGVFKGPNGFEYFAPANTHNNNIEGQAIVYQN
                     KFLTLNGKKYYFDNDSKAVTGWQTIDGKKYYFNLNTAEAATGWQTIDGKKYYFNLNTA
                     EAATGWQTIDGKKYYFNTNTFIASTGYTSINGKHFYFNTDGIMQIGVFKGPNGFEYFA
                     PANTDANNIEGQAILYQNKFLTLNGKKYYFGSDSKAVTGLRTIDGKKYYFNTNTAVAV
                     TGWQTINGKKYYFNTNTSIASTGYTIISGKHFYFNTDGIMQIGVFKGPDGFEYFAPAN
                     TDANNIEGQAIRYQNRFLYLHDNIYYFGNNSKAATGWVTIDGNRYYFEPNTAMGANGY
                     KTIDNKNFYFRNGLPQIGVFKGSNGFEYFAPANTDANNIEGQAIRYQNRFLHLLGKIY
                     YFGNNSKAVTGWQTINGKVYYFMPDTAMAAAGGLFEIDGVIYFFGVDGVKAPGIYG"
     gene            complement(17922..18602)
                     /gene="tcdC"
                     /locus_tag="PC494_002710"
     CDS             complement(17922..18602)
                     /gene="tcdC"
                     /locus_tag="PC494_002710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosylating toxin anti-sigma factor TcdC"
                     /protein_id="HDF3913201.1"
                     /translation="MFSKKNEGNEFSNEGKGSSKKIIKFFKSTKGIALLAFILGVFFG
                     NISSPACSEDHEEVISNQTSVIDSQKTEIETLNSKLSDAEPWFKMKDDEKKAIEAENQ
                     RKAEEAKKAEEQRKKEEEEKKGYDTGITYDQLARTPDDYKYKKVKFEGKVIQVIEDGD
                     EVQIRLAVSGNYDKVVLCSYKKSITPSRVLEDDYITIRGISAGTITYESTMGGNITIP
                     GIAVEKIN"
BASE COUNT         7456 a         2080 c         2911 g         6394 t
ORIGIN      
        1 tattcataat gcatattttc atataaaatt taatttattt gccgattata taattataat
       61 gactgattta attccaatgt tgtcaaaatt ttcgaataaa tcatcattat aaatataaga
      121 gaggatgatt ttatgcaaaa gtctttttat gaattaattg ttttagcaag aaataactca
      181 gtagatgatt tgcaagaaat tttatttatg tttaagccat tagtaaaaaa acttagtaga
      241 gttttacatt atgaagaggg agaaacagat ttaataatat tttttattga attaataaaa
      301 aatattaaat taagtagctt ttcagaaaaa agcgatgcta ttatagtcaa atatattcat
      361 aaatcattac tgaataagac ttttgagttg tctagaagat attctaaaat gaagtttaat
      421 tttgtagaat ttgatgaaaa tatcttaaat atgaaaaata attatcaaag taagtctgtt
      481 tttgaggaag atatttgttt tttcgaatat attttgaaag aattatctgg tattcaaaga
      541 aaagttattt tttataaata tttaaaagga tattctgata gagaaatatc agtgaaatta
      601 aaaatatcta gacaagctgt taataaggct aaaaatagag catttaaaaa aataaaaaaa
      661 gactatgaaa attattttaa cttgtaatta atgagcttaa agaaatattt acaatagaaa
      721 tcaaatttta gaattaactt tattgtaaaa tcaataactt aatctaagaa tatcttaatt
      781 tttatatttt atatagaaca aagtttacat atttatttca gacaacgtct ttattcaatc
      841 gaagagcaaa ttaatcaact gagtgtcttc aatttaaaat gttaggaagt gaatgtatat
      901 gaaaacctaa gtagatatta gtatatttta taaatagaaa ggaggatata taaaagagtt
      961 ttatcattta gatgtaaaaa tattatagta aaggagaaaa ttttatgagt ttagttaata
     1021 gaaaacagtt agaaaaaatg gcaaatgtaa gatttcgtac tcaagaagat gaatatgttg
     1081 caatattgga tgctttagaa gaatatcata atatgtcaga gaatactgta gtcgaaaaat
     1141 atttaaaatt aaaagatata aatagtttaa cagatattta tatagataca tataaaaaat
     1201 ctggtagaaa taaagcctta aaaaaattta aggaatatct agttacagaa gtattagagc
     1261 taaagaataa taatttaact ccagttgaga aaaatttaca ttttgtttgg attggaggtc
     1321 aaataaatga cactgctatt aattatataa atcaatggaa agatgtaaat agtgattata
     1381 atgttaatgt tttttatgat agtaatgcat ttttgataaa cacattgaaa aaaactgtag
     1441 tagaatcagc aataaatgat acacttgaat catttagaga aaacttaaat gaccctagat
     1501 ttgactataa taaattcttc agaaaacgta tggaaataat ttatgataaa cagaaaaatt
     1561 tcataaacta ctataaagct caaagagaag aaaatcctga acttataatt gatgatattg
     1621 taaagacata tctttcaaat gagtattcaa aggagataga tgaacttaat acctatattg
     1681 aagaatcctt aaataaaatt acacagaata gtggaaatga tgttagaaac tttgaagaat
     1741 ttaaaaatgg agagtcattc aacttatatg aacaagagtt ggtagaaagg tggaatttag
     1801 ctgctgcttc tgacatatta agaatatctg cattaaaaga aattggtggt atgtatttag
     1861 atgttgatat gttaccagga atacaaccag acttatttga gtctatagag aaacctagtt
     1921 cagtaacagt ggatttttgg gaaatgacaa agttagaagc tataatgaaa tacaaagaat
     1981 atataccaga atatacctca gaacattttg acatgttaga cgaagaagtt caaagtagtt
     2041 ttgaatctgt tctagcttct aagtcagata aatcagaaat attctcatca cttggtgata
     2101 tggaggcatc accactagaa gttaaaattg catttaatag taagggtatt ataaatcaag
     2161 ggctaatttc tgtgaaagac tcatattgta gcaatttaat agtaaaacaa atcgagaata
     2221 gatataaaat attgaataat agtttaaatc cagctattag cgaggataat gattttaata
     2281 ctacaacgaa tacctttatt gatagtataa tggctgaagc taatgcagat aatggtagat
     2341 ttatgatgga actaggaaag tatttaagag ttggtttctt cccagatgtt aaaactacta
     2401 ttaacttaag tggccctgaa gcatatgcgg cagcttatca agatttatta atgtttaaag
     2461 aaggcagtat gaatatccat ttgatagaag ctgatttaag aaactttgaa atctctaaaa
     2521 ctaatatttc tcaatcaact gaacaagaaa tggctagctt atggtcattt gacgatgcaa
     2581 gagctaaagc tcaatttgaa gaatataaaa ggaattattt tgaaggttct cttggtgaag
     2641 atgataatct tgatttttct caaaatatag tagttgacaa ggagtatctt ttagaaaaaa
     2701 tatcttcatt agcaagaagt tcagagagag gatatataca ctatattgtt cagttacaag
     2761 gagataaaat tagttatgaa gcagcatgta acttatttgc aaagactcct tatgatagtg
     2821 tactgtttca gaaaaatata gaagattcag aaattgcata ttattataat cctggagatg
     2881 gtgaaataca agaaatagac aagtataaaa ttccaagtat aatttctgat agacctaaga
     2941 ttaaattaac atttattggt catggtaaag atgaatttaa tactgatata tttgcaggtt
     3001 ttgatgtaga ttcattatcc acagaaatag aagcagcaat agatttagct aaagaggata
     3061 tttctcctaa gtcaatagaa ataaatttat taggatgtaa tatgtttagc tactctatca
     3121 acgtagagga gacttatcct ggaaaattat tacttaaagt taaagataaa atatcagaat
     3181 taatgccatc tataagtcaa gactctatta tagtaagtgc aaatcaatat gaagttagaa
     3241 taaatagtga aggaagaaga gaattattag accattctgg tgaatggata aacaaagaag
     3301 aaagtattat aaaggatatt tcatcaaaag aatatatatc atttaatcct aaagaaaata
     3361 aaattacagt aaaatctaaa aatttacctg agctatctac attattacaa gaaattagaa
     3421 ataattctaa ttcaagtgat attgaactag aagaaaaagt aatgttaaca gaatgtgaga
     3481 taaatgttat ttcaaatata gatacgcaaa ttgttgagga aaggattgaa gaagctaaga
     3541 atttaacttc tgactctatt aattatataa aagatgaatt taaactaata gaatctattt
     3601 ctgatgcact atgtgactta aaacaacaga atgaattaga agattctcat tttatatctt
     3661 ttgaggacat atcagagact gatgagggat ttagtataag atttattaat aaagaaactg
     3721 gagaatctat atttgtagaa actgaaaaaa caatattctc tgaatatgct aatcatataa
     3781 ctgaagagat ttctaagata aaaggtacta tatttgatac tgtaaatggt aagttagtaa
     3841 aaaaagtaaa tttagatact acacacgaag taaatacttt aaatgctgca ttttttatac
     3901 aatcattaat agaatataat agttctaaag aatctcttag taatttaagt gtagcaatga
     3961 aagtccaagt ttacgctcaa ttatttagta ctggtttaaa tactattaca gatgcagcca
     4021 aagttgttga attagtatca actgcattag atgaaactat agacttactt cctacattat
     4081 ctgaaggatt acctataatt gcaactatta tagatggtgt aagtttaggt gcagcaatca
     4141 aagagctaag tgaaacgagt gacccattat taagacaaga aatagaagct aagataggta
     4201 taatggcagt aaatttaaca acagctacaa ctgcaatcat tacttcatct ttggggatag
     4261 ctagtggatt tagtatactt ttagttcctt tagcaggaat ttcagcaggt ataccaagct
     4321 tagtaaacaa tgaacttgta cttcgagata aggcaacaaa ggttgtagat tattttaaac
     4381 atgtttcatt agttgaaact gaaggagtat ttactttatt agatgataaa ataatgatgc
     4441 cacaagatga tttagtgata tcagaaatag attttaataa taattcaata gttttaggta
     4501 aatgtgaaat ctggagaatg gaaggtggtt caggtcatac tgtaactgat gatatagatc
     4561 acttcttttc agcaccatca ataacatata gagagccaca cttatctata tatgacgtat
     4621 tggaagtaca aaaagaagaa cttgatttgt caaaagattt aatggtatta cctaatgctc
     4681 caaatagagt atttgcttgg gaaacaggat ggacaccagg tttaagaagc ttagaaaatg
     4741 atggcacaaa actgttagac cgtataagag ataactatga aggtgagttt tattggagat
     4801 attttgcttt tatagctgat gctttaataa caacattaaa accaagatat gaagatacta
     4861 atataagaat aaatttagat agtaatacta gaagttttat agttccaata ataactacag
     4921 aatatataag agaaaaatta tcatattctt tctatggttc aggaggaact tatgcattgt
     4981 ctctttctca atataatatg ggtataaata tagaattaag tgaaagtgat gtttggatta
     5041 tagatgttga taatgttgtg agagatgtaa ctatagaatc tgataaaatt aaaaaaggtg
     5101 atttaataga aggtatttta tctacactaa gtattgaaga gaataaaatt atcttaaata
     5161 gccatgagat taatttttct ggtgaggtaa atggaagtaa tggatttgtt tctttaacat
     5221 tttcaatttt agaaggaata aatgcaatta tagaagttga tttattatct aaatcatata
     5281 aattacttat ttctggcgaa ttaaaaatat tgatgttaaa ttcaaatcat attcaacaga
     5341 aaatagatta tataggattc aatagcgaat tacagaaaaa tataccatat agctttgtag
     5401 atagtgaagg aaaagagaat ggttttatta atggttcaac aaaagaaggt ttatttgtat
     5461 ctgaattacc tgatgtagtt cttataagta aggtttatat ggatgatagt aagccttcat
     5521 ttggatatta tagtaataat ttgaaagatg tcaaagttat aactaaagat aatgttaata
     5581 tattaacagg ttattatctt aaggatgata taaaaatctc tctttctttg actctacaag
     5641 atgaaaaaac tataaagtta aatagtgtgc atttagatga aagtggagta gctgagattt
     5701 tgaagttcat gaatagaaaa ggtaatacaa atacttcaga ttctttaatg agctttttag
     5761 aaagtatgaa tataaaaagt attttcgtta atttcttaca atctaatatt aagtttatat
     5821 tagatgctaa ttttataata agtggtacta cttctattgg ccaatttgag tttatttgtg
     5881 atgaaaatga taatatacaa ccatatttca ttaagtttaa tacactagaa actaattata
     5941 ctttatatgt aggaaataga caaaatatga tagtggaacc aaattatgat ttagatgatt
     6001 ctggagatat atcttcaact gttatcaatt tctctcaaaa gtatctttat ggaatagaca
     6061 gttgtgttaa taaagttgta atttcaccaa atatttatac agatgaaata aatataacgc
     6121 ctgtatatga aacaaataat acttatccag aatttattgt attagatgca aattatataa
     6181 atgaaaaaat aaatgttaat atcaatgatc tatctatacg atatgtatgg agtaatgatg
     6241 gtaatgattt tattcttatg tcaactagtg aagaaaataa ggtgtcacaa gttaaaataa
     6301 gattcgttaa tgtttttaaa gataagactt tggcaaataa gctatctttt aactttagtg
     6361 ataaacaaga tgtacctgta agtgaaataa tcttatcatt tacaccttca tattatgagg
     6421 atggattgat tggctatgat ttgggtctag tttctttata taatgagaaa ttttatatta
     6481 ataactttgg aatgatgcta tctggattaa tatatattaa tgattcatta tattatttta
     6541 aaccaccagt aaataatttg ataactggat ttgtgactgt aggcgatgat aaatactact
     6601 ttaatccaat taatggtgga gctgcttcaa ttggagagac aataattgat gacaaaaatt
     6661 attatttcaa ccaaagtgga gtgttacaaa caggtgtatt tagtacagaa gatggattta
     6721 aatattttgc cccagctaat acacttgatg aaaacctaga aggagaagca attgatttta
     6781 ctggaaaatt aattattgac gaaaatattt attattttga tgataattat agaggagctg
     6841 tagaatggaa agaattagat ggtgaaatgc actattttag cccagaaaca ggtaaagctt
     6901 ttaaaggtct aaatcaaata ggtgatgata aatactattt caattctgat ggagttatgc
     6961 aaaaaggatt tgttagtata aatgataata aacactattt tgatgattct ggtgttatga
     7021 aagtaggtta cactgaaata gatggcaagc atttctactt tgctgaaaac ggagaaatgc
     7081 aaataggagt atttaataca gaagatggat ttaaatattt tgctcatcat aatgaagatt
     7141 taggaaatga agaaggtgaa gaaatctcat attctggtat attaaatttc aataataaaa
     7201 tttactattt tgatgattca tttacagctg tagttggatg gaaagattta gaggatggtt
     7261 caaagtatta ttttgatgaa gatacagcag aagcatatat aggtttgtca ttaataaatg
     7321 atggtcaata ttattttaat gatgatggaa ttatgcaagt tggatttgtc actataaatg
     7381 ataaagtctt ctacttctct gactctggaa ttatagaatc tggagtacaa aacatagatg
     7441 acaattattt ctatatagat gataatggta tagttcaaat tggtgtattt gatacttcag
     7501 atggatataa atattttgca cctgctaata ctgtaaatga taatatttac ggacaagcag
     7561 ttgaatatag tggtttagtt agagttgggg aagatgtata ttattttgga gaaacatata
     7621 caattgagac tggatggata tatgatatgg aaaatgaaag tgataaatat tatttcaatc
     7681 cagaaactaa aaaagcatgc aaaggtatta atttaattga tgatataaaa tattattttg
     7741 atgagaaggg cataatgaga acgggtctta tatcatttga aaataataat tattacttta
     7801 atgagaatgg tgaaatgcaa tttggttata taaatataga agataagatg ttctattttg
     7861 gtgaagatgg tgtcatgcag attggagtat ttaatacacc agatggattt aaatactttg
     7921 cacatcaaaa tactttggat gagaattttg agggagaatc aataaactat actggttggt
     7981 tagatttaga tgaaaagaga tattatttta cagatgaata tattgcagca actggttcag
     8041 ttattattga tggtgaggag tattattttg atcctgatac agctcaatta gtgattagtg
     8101 aatagataaa aatatgttaa atatatcctc ttatacttaa atatataaaa ataaacaaaa
     8161 tgatacacta cataaagtgt tctatctaat atgaagattt accaataaaa aggtggacta
     8221 tgatgaatgc acagtagttc acctttttat atttctaatg gtaacaaaat atttttttat
     8281 ataaacctag gaggcgttat gaatatgaca atatcttttt tatcagagca tatatttata
     8341 aagttagtaa ttttaactat atcatttgat acattattag gatgtttaag tgcaataaaa
     8401 agtcgtaaat ttaattctag ttttggaata gatggaggaa tcagaaaagt agcaatgata
     8461 gcatgtatat tttttttatc agtagttgac attcttacaa agtttaactt tttatttatg
     8521 ttaccacaag attgtatcaa ttttttaaga ctaaaacatc ttggaatatc tgaatttttc
     8581 tctattttat ttattttata tgaaagtgta agtatattaa aaaatatgtg cttatgtgga
     8641 ttaccagtac ctaagagatt aaaggaaaaa atagcaattt tactagatgc aatgacagat
     8701 gaaatgaatg ctaaggatga aaagtaagta atggtagata taataaagat attaacaaat
     8761 aaaaagtgtt atccaaataa gaatagctga aagttatcat aattcatgaa actaataatg
     8821 aaaacgaggg agcagatgcc aagagacaca caagtattaa atacatataa tttcgaagca
     8881 agtgttcatt actatataga tgacaaggta gtatatcaaa cattggttca caaagatggt
     8941 gcatggtcag ttggtaaaat ctattaagct acattagtta cagatatcac aaactataat
     9001 agttaaacat agaaatatgt gtaaattgtg atggaaatta ttcaaaaaca caaaaatacg
     9061 tgatgaagga caaaatgata tagaaaataa gtatcaaacc ttaataaatg atttaattga
     9121 tagtttaaaa gttataggaa aaatatataa agaaataaaa acattaaaaa aatataagat
     9181 atgtttacaa attactatca gacaatctcc ttatctaata gaagagtcaa ttaactaatt
     9241 gagtatcttt aaattgaaat gttaggaagt gatttaaata tgaaaactta aattataaaa
     9301 aatcaatatt aatttatttt taaaaaatag aaaggagtgt ataagattta ttttcaaagt
     9361 ttaaaaacaa gaaaatcaat ttaaatttca gaaggaataa atgtggttat agaagtggat
     9421 ttattatcaa aaataataat actaggaggt ttttatgtct ttaatatcta aagaagagtt
     9481 aataaaactc gcatatagca ttagaccaag agaaaatgag tataaaacta tactaactaa
     9541 tttagacgaa tataataagt taactacaaa caataatgaa aataaatatt tacaattaaa
     9601 aaaactaaat gaatcaattg atgtttttat gaataaatat aaaacttcaa gcagaaatag
     9661 agcactctct aatctaaaaa aagatatatt aaaagaagta attcttatta aaaattccaa
     9721 tacaagccct gtagaaaaaa atttacattt tgtatggata ggtggagaag tcagtgatat
     9781 tgctcttgaa tacataaaac aatgggctga tattaatgca gaatataata ttaaactgtg
     9841 gtatgatagt gaagcattct tagtaaatac actaaaaaag gctatagttg aatcttctac
     9901 cactgaagca ttacagctac tagaggaaga gattcaaaat cctcaatttg ataatatgaa
     9961 attttacaaa aaaaggatgg aatttatata tgatagacaa aaaaggttta taaattatta
    10021 taaatctcaa atcaataaac ctacagtacc tacaatagat gatattataa agtctcatct
    10081 agtatctgaa tataatagag atgaaactgt attagaatca tatagaacaa attctttgag
    10141 aaaaataaat agtaatcatg ggatagatat cagggctaat agtttgttta cagaacaaga
    10201 gttattaaat atttatagtc aggagttgtt aaatcgtgga aatttagctg cagcatctga
    10261 catagtaaga ttattagccc taaaaaattt tggcggagta tatttagatg ttgatatgct
    10321 tccaggtatt cactctgatt tatttaaaac aatatctaga cctagctcta ttggactaga
    10381 ccgttgggaa atgataaaat tagaggctat tatgaagtat aaaaaatata taaataatta
    10441 tacatcagaa aactttgata aacttgatca acaattaaaa gataatttta aactcattat
    10501 agaaagtaaa agtgaaaaat ctgagatatt ttctaaatta gaaaatttaa atgtatctga
    10561 tcttgaaatt aaaatagctt tcgctttagg cagtgttata aatcaagcct tgatatcaaa
    10621 acaaggttca tatcttacta acctagtaat agaacaagta aaaaatagat atcaattttt
    10681 aaaccaacac cttaacccag ccatagagtc tgataataac ttcacagata ctactaaaat
    10741 ttttcatgat tcattattta attcagctac cgcagaaaac tctatgtttt taacaaaaat
    10801 agcaccatac ttacaagtag gttttatgcc agaagctcgc tccacaataa gtttaagtgg
    10861 tccaggagct tatgcgtcag cttactatga tttcataaat ttacaagaaa atactataga
    10921 aaaaacttta aaagcatcag atttaataga atttaaattc ccagaaaata atctatctca
    10981 attgacagaa caagaaataa atagtctatg gagctttgat caagcaagtg caaaatatca
    11041 atttgagaaa tatgtaagag attatactgg tggatctctt tctgaagaca atggggtaga
    11101 ctttaataaa aatactgccc tcgacaaaaa ctatttatta aataataaaa ttccatcaaa
    11161 caatgtagaa gaagctggaa gtaaaaatta tgttcattat atcatacagt tacaaggaga
    11221 tgatataagt tatgaagcaa catgcaattt attttctaaa aatcctaaaa atagtattat
    11281 tatacaacga aatatgaatg aaagtgcaaa aagctacttt ttaagtgatg atggagaatc
    11341 tattttagaa ttaaataaat ataggatacc tgaaagatta aaaaataagg aaaaagtaaa
    11401 agtaaccttt attggacatg gtaaagatga attcaacaca agcgaatttg ctagattaag
    11461 tgtagattca ctttccaatg agataagttc atttttagat accataaaat tagatatatc
    11521 acctaaaaat gtagaagtaa acttacttgg atgtaatatg tttagttatg attttaatgt
    11581 tgaagaaact tatcctggga agttgctatt aagtattatg gacaaaatta cttccacttt
    11641 acctgatgta aataaaaatt ctattactat aggagcaaat caatatgaag taagaattaa
    11701 tagtgaggga agaaaagaac ttctggctca ctcaggtaaa tggataaata aagaagaagc
    11761 tattatgagc gatttatcta gtaaagaata catttttttt gattctatag ataataagct
    11821 aaaagcaaag tccaagaata ttccaggatt agcatcaata tcagaagata taaaaacatt
    11881 attacttgat gcaagtgtta gtcctgatac aaaatttatt ttaaataatc ttaagcttaa
    11941 tattgaatct tctattggtg attacattta ttatgaaaaa ttagagcctg ttaaaaatat
    12001 aattcacaat tctatagatg atttaataga tgagttcaat ctacttgaaa atgtatctga
    12061 tgaattatat gaattaaaaa aattaaataa tctagatgag aagtatttaa tatcttttga
    12121 agatatctca aaaaataatt caacttactc tgtaagattt attaacaaaa gtaatggtga
    12181 gtcagtttat gtagaaacag aaaaagaaat tttttcaaaa tatagcgaac atattacaaa
    12241 agaaataagt actataaaga atagtataat tacagatgtt aatggtaatt tattggataa
    12301 tatacagtta gatcatactt ctcaagttaa tacattaaac gcagcattct ttattcaatc
    12361 attaatagat tatagtagca ataaagatgt actgaatgat ttaagtacct cagttaaggt
    12421 tcaactttat gctcaactat ttagtacagg tttaaatact atatatgact ctatccaatt
    12481 agtaaattta atatcaaatg cagtaaatga tactataaat gtactaccta caataacaga
    12541 ggggatacct attgtatcta ctatattaga cggaataaac ttaggtgcag caattaagga
    12601 attactagac gaacatgacc cattactaaa aaaagaatta gaagctaagg tgggtgtttt
    12661 agcaataaat atgtcattat ctatagctgc aactgtagct tcaattgttg gaataggtgc
    12721 tgaagttact attttcttat tacctatagc tggtatatct gcaggaatac cttcattagt
    12781 taataatgaa ttaatattgc atgataaggc aacttcagtg gtaaactatt ttaatcattt
    12841 gtctgaatct aaaaaatatg gccctcttaa aacagaagat gataaaattt tagttcctat
    12901 tgatgattta gtaatatcag aaatagattt taataataat tcgataaaac taggaacatg
    12961 taatatatta gcaatggagg ggggatcagg acacacagtg actggtaata tagatcactt
    13021 tttctcatct ccatctataa gttctcatat tccttcatta tcaatttatt ctgcaatagg
    13081 tatagaaaca gaaaatctag atttttcaaa aaaaataatg atgttaccta atgctccttc
    13141 aagagtgttt tggtgggaaa ctggagcagt tccaggttta agatcattgg aaaatgacgg
    13201 aactagatta cttgattcaa taagagattt atacccaggt aaattttact ggagattcta
    13261 tgcttttttc gattatgcaa taactacatt aaaaccagtt tatgaagaca ctaatattaa
    13321 aattaaacta gataaagata ctagaaactt cataatgcca actataacta ctaacgaaat
    13381 tagaaacaaa ttatcttatt catttgatgg agcaggagga acttactctt tattattatc
    13441 ttcatatcca atatcaacga atataaattt atctaaagat gatttatgga tatttaatat
    13501 tgataatgaa gtaagagaaa tatctataga aaatggtact attaaaaaag gaaagttaat
    13561 aaaagatgtt ttaagtaaaa ttgatataaa taaaaataaa cttattatag gcaatcaaac
    13621 aatagatttt tcaggcgata tagataataa agatagatat atattcttga cttgtgagtt
    13681 agatgataaa attagtttaa taatagaaat aaatcttgtt gcaaaatctt atagtttgtt
    13741 attgtctggg gataaaaatt atttgatatc caatttatct aatactattg agaaaatcaa
    13801 tactttaggc ctagatagta aaaatatagc gtacaattac actgatgaat ctaataataa
    13861 atattttgga gctatatcta aaacaagtca aaaaagcata atacattata aaaaagacag
    13921 taaaaatata ttagaatttt ataatgacag tacattagaa tttaacagta aagattttat
    13981 tgctgaagat ataaatgtat ttatgaaaga tgatattaat actataacag gaaaatacta
    14041 tgttgataat aatactgata aaagtataga tttctctatt tctttagtta gtaaaaatca
    14101 agtaaaagta aatggattat atttaaatga atccgtatac tcatcttacc ttgattttgt
    14161 gaaaaattca gatggacacc ataatacttc taattttatg aatttatttt tggacaatat
    14221 aagtttctgg aaattgtttg ggtttgaaaa tataaatttt gtaatcgata aatactttac
    14281 ccttgttggt aaaactaatc ttggatatgt agaatttatt tgtgacaata ataaaaatat
    14341 agatatatat tttggtgaat ggaaaacatc gtcatctaaa agcactatat ttagcggaaa
    14401 tggtagaaat gttgtagtag agcctatata taatcctgat acgggtgaag atatatctac
    14461 ttcactagat ttttcctatg aacctctcta tggaatagat agatatatca ataaagtatt
    14521 gatagcacct gatttatata caagtttaat aaatattaat accaattatt attcaaatga
    14581 gtactaccct gagattatag ttcttaaccc aaatacattc cacaaaaaag taaatataaa
    14641 tttagatagt tcttcttttg agtataaatg gtctacagaa ggaagtgact ttattttagt
    14701 tagatactta gaagaaagta ataaaaaaat attacaaaaa ataagaatca aaggtatctt
    14761 atctaatact caatcattta ataaaatgag tatagatttt aaagatatta aaaaactatc
    14821 attaggatat ataatgagta attttaaatc atttaattct gaaaatgaat tagatagaga
    14881 tcatttagga tttaaaataa tagataataa aacttattac tatgatgaag atagtaaatt
    14941 agttaaagga ttaatcaata taaataattc attattctat tttgatccta tagaatttaa
    15001 cttagtaact ggatggcaaa ctatcaatgg taaaaaatat tattttgata taaatactgg
    15061 agcagcttta actagttata aaattattaa tggtaaacac ttttatttta ataatgatgg
    15121 tgtgatgcag ttgggagtat ttaaaggacc tgatggattt gaatattttg cacctgccaa
    15181 tactcaaaat aataacatag aaggtcaggc tatagtttat caaagtaaat tcttaacttt
    15241 gaatggcaaa aaatattatt ttgataatga ctcaaaagca gtcactggat ggagaattat
    15301 taacaatgag aaatattact ttaatcctaa taatgctatt gctgcagtcg gattgcaagt
    15361 aattgacaat aataagtatt atttcaatcc tgacactgct atcatctcaa aaggttggca
    15421 gactgttaat ggtagtagat actactttga tactgatacc gctattgcct ttaatggtta
    15481 taaaactatt gatggtaaac acttttattt tgatagtgat tgtgtagtga aaataggtgt
    15541 gtttagtacc tctaatggat ttgaatattt tgcacctgct aatacttata ataataacat
    15601 agaaggtcag gctatagttt atcaaagtaa attcttaact ttgaatggta aaaaatatta
    15661 ctttgataat aactcaaaag cagttaccgg atggcaaact attgatagta aaaaatatta
    15721 ctttaatact aacactgctg aagcagctac tggatggcaa actattgatg gtaaaaaata
    15781 ttactttaat actaacactg ctgaagcagc tactggatgg caaactattg atggtaaaaa
    15841 atattacttt aatactaaca ctgctatagc ttcaactggt tatacaatta ttaatggtaa
    15901 acatttttat tttaatactg atggtattat gcagatagga gtgtttaaag gacctaatgg
    15961 atttgaatat tttgcacctg ctaatacgga tgctaacaac atagaaggtc aagctatact
    16021 ttaccaaaat gaattcttaa ctttgaatgg taaaaaatat tactttggta gtgactcaaa
    16081 agcagttact ggatggagaa ttattaacaa taagaaatat tactttaatc ctaataatgc
    16141 tattgctgca attcatctat gcactataaa taatgacaag tattacttta gttatgatgg
    16201 aattcttcaa aatggatata ttactattga aagaaataat ttctattttg atgctaataa
    16261 tgaatctaaa atggtaacag gagtatttaa aggacctaat ggatttgagt attttgcacc
    16321 tgctaatact cacaataata acatagaagg tcaggctata gtttaccaga acaaattctt
    16381 aactttgaat ggcaaaaaat attattttga taatgactca aaagcagtta ctggatggca
    16441 aaccattgat ggtaaaaaat attactttaa tcttaacact gctgaagcag ctactggatg
    16501 gcaaactatt gatggtaaaa aatattactt taatcttaac actgctgaag cagctactgg
    16561 atggcaaact attgatggta aaaaatatta ctttaatact aacactttca tagcctcaac
    16621 tggttataca agtattaatg gtaaacattt ttattttaat actgatggta ttatgcagat
    16681 aggagtgttt aaaggaccta atggatttga atactttgca cctgctaata cggatgctaa
    16741 caacatagaa ggtcaagcta tactttacca aaataaattc ttaactttga atggtaaaaa
    16801 atattacttt ggtagtgact caaaagcagt taccggattg cgaactattg atggtaaaaa
    16861 atattacttt aatactaaca ctgctgttgc agttactgga tggcaaacta ttaatggtaa
    16921 aaaatactac tttaatacta acacttctat agcttcaact ggttatacaa ttattagtgg
    16981 taaacatttt tattttaata ctgatggtat tatgcagata ggagtgttta aaggacctga
    17041 tggatttgaa tactttgcac ctgctaatac agatgctaac aatatagaag gtcaagctat
    17101 acgttatcaa aatagattcc tatatttaca tgacaatata tattattttg gtaataattc
    17161 aaaagcggct actggttggg taactattga tggtaataga tattacttcg agcctaatac
    17221 agctatgggt gcgaatggtt ataaaactat tgataataaa aatttttact ttagaaatgg
    17281 tttacctcag ataggagtgt ttaaagggtc taatggattt gaatactttg cacctgctaa
    17341 tacggatgct aacaatatag aaggtcaagc tatacgttat caaaatagat tcctacattt
    17401 acttggaaaa atatattact ttggtaataa ttcaaaagca gttactggat ggcaaactat
    17461 taatggtaaa gtatattact ttatgcctga tactgctatg gctgcagctg gtggactttt
    17521 cgagattgat ggtgttatat atttctttgg tgttgatgga gtaaaagccc ctgggatata
    17581 tggctaaaat atatgtttga taaaaaatta ttcctgtgct actaagaaat tatttttata
    17641 taataaatat tgagatttaa ttaaaagtca tgtgttattg taatacatga cttttagtta
    17701 aaatttttct atcatttaat aatctattat tcttgactat tttataataa aattcatata
    17761 tggaaatatt aatactaaat aattaatagt tgataaaaaa tagataatat gctaaaagca
    17821 aaaactaatt tagagccttg taactgttta tttgcaatta taaaaacatc tttaaacata
    17881 ttgactataa tataaaatat taactataat acaaaacaat attaattaat tttctctaca
    17941 gctatccctg gtatagttat atttccaccc atagttgatt cataagttat agttccagca
    18001 cttatacctc ttatagttat gtaatcatcc tctaatactc ttgaaggagt tattgatttt
    18061 ttataactac atagtacaac cttatcataa tttccagaca cagctaatct tatttgcacc
    18121 tcatcaccat cttcaataac ttgaataacc ttaccttcaa attttacctt tttgtactta
    18181 taatcatcag gtgttctagc taattggtca taagtaatac cagtatcata tcctttcttc
    18241 tcctcttctt cttttttgcg ttgttcttca gcctttttag cttcttcagc tttacgttga
    18301 ttttcagctt caatagcttt cttttcgtcg tctttcattt tgaaccatgg ttcagcatca
    18361 gacaatttgc tatttaaagt ttctatttct gttttttgag aatctataac tgatgtttgg
    18421 ttagaaatga cctcctcatg gtcttcagaa caagctggtg aggatatatt gccaaaaaac
    18481 acgcctaaaa taaatgccag tagagcaata ccctttgtgc tcttaaagaa tttaattatt
    18541 ttcttagagc ttccttttcc ttcattacta aattcgttac cctcattttt tttagaaaac
    18601 ataatacaat ctccctttta ttagatatat tttattttaa aagttaaaaa cttaaaataa
    18661 ctagttgact aaaaattata tattcatatt ttcctaaaat atatttcccc taagcataat
    18721 tttacaaaat aaagtaagaa gattcaatat attttgaaaa aataagataa aaatgtcaga
    18781 ttataatata attttcttga aggtgaattt tatatattaa attaaacata aagtatttta
    18841 t
//
LOCUS       DAMKNB010000069        18742 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.071, whole genome shotgun sequence.
ACCESSION   DAMKNB010000069 DAMKNB010000000
VERSION     DAMKNB010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 18742)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18742)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18742
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.071"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            complement(72..608)
                     /locus_tag="PC494_002711"
     CDS             complement(72..608)
                     /locus_tag="PC494_002711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB-like nuclease domain-containing protein"
                     /protein_id="HDF3913202.1"
                     /translation="MEYKSPVYGIIAVPIEKIESNDYNPNAVAPPEMQLLYKSIKEDG
                     YTMPIVCYYNEEKDKYIIVDGFHRYRVMLENEDIYDRENGLLPVSVIDKSLDERMAST
                     IRHNRARGSHNVDLMSKIITELCEIGKSDEWISKHLGMEVDEILRLKQITGLAYLFKD
                     KEFGNAWIPFGSDIEEEN"
     gene            complement(626..1939)
                     /locus_tag="PC494_002712"
     CDS             complement(626..1939)
                     /locus_tag="PC494_002712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3440 domain-containing protein"
                     /protein_id="HDF3913203.1"
                     /translation="MDKRYLESDVFEAFQERLSYLFNEFDYIYVSFSGGKDSGLLLNL
                     VLDYKRKNNISSKIGVFHQDFEAQYSLTTEYVEKVFEDNIEDIEPYWVCLPMATRTAV
                     GNYEMYWYPWDDEKEELWVREMPVKEYIINQKNNPFTYYKYKMRQESLAKQFGRWIRD
                     IHEGAKVVCLLGTRAAESLQRYCSIVNKQHGYKGKCWITKEFKNVWTASPIYDWEIED
                     IWLAHYKFDYDYNKIYDLFYKAGVAPRKMRVASPFNDSAKESLNLYRILDPDVWVKLV
                     ARVQGVNFTSIYGKTKAMGYRSVKLPYGHTWKSFTYFLLDTLPENIRNSYIKKFSTSI
                     EFWQNTGGGLSEIVIRELLRKGYKIELNGVSNHTKDKKSRVIFLDDIPDDTDDIKFTK
                     DIPSWKRMCYCILKNDHMCRFMGFGPTKEQRIRTEYIKKKYEKIH"
     gene            2294..2734
                     /locus_tag="PC494_002713"
     CDS             2294..2734
                     /locus_tag="PC494_002713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3788 domain-containing protein"
                     /protein_id="HDF3913204.1"
                     /translation="MYERMLDKSNKPCLSQIIEYIGKDGYARLCKLETYLKTQYNLSR
                     ELRFPFGNNYGWGYKYSHKSFHLFYAFFEKGAFTVLIQIGDKQVPAVEKTLVALTPKA
                     KELWVTRYPCGNNGGWIKYRILEDADLLDIIQYIRAKKSPPKQN"
     gene            complement(2919..3107)
                     /locus_tag="PC494_002714"
     CDS             complement(2919..3107)
                     /locus_tag="PC494_002714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3913205.1"
                     /translation="MNKNNNLVIICMFIGMILGMAIGCAIGISKGNVGITMCYGLIFG
                     MIIGICIGTVIKNSNKKE"
     gene            4048..4443
                     /locus_tag="PC494_002715"
     CDS             4048..4443
                     /locus_tag="PC494_002715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3913206.1"
                     /translation="MNILKMKKTGIFLGGVLFGTVGVKILSSDCVKKTCTRATAGALK
                     VKDSVLETTTKIQENVEDILAEAKEINEQEDLSTSKVNVVQDTLKCEQEVLKTETIKT
                     VEDTNSNSIKCEEIKDNVIEEKNSTCTTE"
     gene            4486..6585
                     /locus_tag="PC494_002716"
     CDS             4486..6585
                     /locus_tag="PC494_002716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HDF3913207.1"
                     /translation="MNFYIKHEIRGRIRFDLQLGKLNNKQSDTLLYYLTSINGITKAK
                     VYDRTGDAVIYYTGEREYIIREITKFSFNNSKIENLVPEHTSRELNNYYRDKLANKLL
                     VKSISKIFFPKSLRFFLIGLHSIKYFKKGLSSLLNKKIEVSVLDATAIGISIFRKDIN
                     TAGSVMFLLGIGELLEEWTRKKSIDDLAQSMSLNIEKVWLRKGDTEILIPISEIKEGD
                     LVSVTMGNMIPLDGVIVSGETMVNQASLTGESLAVNKKEGSYIYAGTVIEQGNIVMCV
                     KEKAGTTRFQKIVTMIEESEKLKSSVESKFEHLADTLVPYSFLGSILTYAITRNPIKS
                     LSILMVDFSCALKLSIPISVLSAMRECNNNNITVKGGKFLEGVACADTIVFDKTGTLT
                     KAQPTVSDIITFQNYNKEDMLRLAACLEEHFPHSIANAVVYEAEKQGLSHKEMHTEVE
                     YIIAHGISTKVDDKKVVIGSKHFVFEDEKCTIPDGEEDKYNNLSDEYSHLFMAISGKL
                     SAVICINDPLRKEAKYVISNLRECGIKKIVMMTGDSEKTAKSIASKVGVDEYYSEVLP
                     EDKANFVKSEKLKGRKVIMIGDGINDSPAISESDVGIAMSEGAEIAREISDITISADN
                     LNNLIVLKQISNKLMKRVDLSSKFIIGFNLGLILLGVGGFVRPSTSAFLHNASTVGIS
                     LNSMTNLLENTNTYNYH"
     gene            complement(6810..12020)
                     /locus_tag="PC494_002717"
     CDS             complement(6810..12020)
                     /locus_tag="PC494_002717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosome-binding GTPase"
                     /protein_id="HDF3913208.1"
                     /translation="MANKLYSEIVNLLEEGRDELRKYDLKEKSILLFLGASGVGKSTC
                     INYLKGCVMEEKTDEETGQIYITAKDSAVEIGNGVYSKTLCPEVVDIANRDFSLCDCP
                     GFFDNRGAEYMIAGAMLVRETISTSSKVKGMVVILDYQSLLDSRHTLLIETGKNLKDM
                     LGDYAKYKENFFFLINKIPKALIGNVTEEKIRNILKKAKEDLDSQEKDYDGYKELVYL
                     LNVALSDGVSIKLCNPLDKQPEKLLNEMKNLPETFEKTDLGLMLTASCKIEIQKAVDV
                     TYKDLEKLLVPYIESVKKGMEDSISILSSINSLKDKKIQLDKMYTDLCSRTNNMKELM
                     EFVQELSYGDGVQKVNILEETRLLLELNSYCSETHIVGLSELLKSLLKNTLEDTLKDI
                     KYWIAEEEYREEEAKKLEDAEYRIEKIQSCTYIKSYEKENVLSIYIPIPKVNLSDLTK
                     IISGYQLNILSSIYMYGDCELKIDCNMEKEVFSGKNIVLLTEKLHIPEGTYSINVSGK
                     DAEKLVGESSIYDGMNGRNGNNAGTSGDIILSFKEIEKRGELKLYVDGGRGGNGQDGK
                     KGDTGITGEAGANAKIGSKKESKEFANVKGTKYYVVKAEKGKQGGTGGTGGNGGNAGL
                     GSKSGQVYLLGKAPLLKSAISKKDGNHGLAGKGGSGGAGGAGGLGGIRGIYEETIRYI
                     GTSPPMDNSDRNYYYFDRYVFNHALNQKQAADDGEKLNTLYEEHKDWTISKREDSGSA
                     GAEGKAGHSGDALKEKELLKQEYSLSIDTFFYEFFERFGFSGIKGYRNLRLLCAVGIL
                     EADILELSHIYEIFHAVEKIEMQLNREILQKYYSFEKKNKAVLSLDDMNTKKEFYKEA
                     KEIYEYLINKLMQSDRIESFVGKNQNFSEWSMILFALEQKTAFYVQMIEESEIGGNRV
                     TDIRSLTDYLDKTLRELEQGKKDELKEGYFNTYKESILTQIESGNQQIEVLKNELENK
                     MLSVNAKMNLLIQEIIKMKEDEQEDIEELKKKQAKLEEQMKTQLILSGIQSALSLLTA
                     FSGVGQACLGAFDSAKSLKENLSSKEEEYKWTNRMVNFSDFKLDSDGMRFVLGEQLSE
                     DRKNALDKMTYNLAGVDEERRTKFDQIKEIIVKSIDDDNYADKADDIQRAKEGLSESE
                     YKEIYTKIQKKEIGMLEANYNNKQQKDKLAALEKSKQAIERQQKTSKIKNALSIGSSA
                     CSLINTAISGVNNCLNVKSSFESKIEVVKEAIKDKENNIKKLDELNTQMVEFKDKTLK
                     ESVIPFVEKFDSTVKNQDIFENEISKLKMKEVLTELSTKFGSLKMENSEEISIIFKKV
                     QDMMETQIIITDKIDKKKDNLAMGELIYQMSDSGNQMNEYQKKLIHQIELNQVRYLCQ
                     VEAAAFQLWTFPFGSNIVNILNRCHVGITEDENEVINQAKEQNRQIREFLDQDAYQWQ
                     KTDNHILKVALTGSLDGKSRVGFENTYSLYDCNEEEVKKLLTGDEISFEVPLNKNFDA
                     IKYVTMYANIPNLRRNILEDSLKVKVHIHLYDSGYFSLYDDKKDVYYQYVFPQNYINI
                     THGLDVKYNDSDSINSIWSSVEDKGIEKFKNAGLNSGRSPYSMAKISLKAHFNRKLSY
                     DSLTNEQKKKLESYFDKPSKYAWSDSIDILRSLGYIDLKGILSKSWYEIKKDIDSDGE
                     IMKHFSILQVDLLERIIYEQTSILKENIPNLTIELVGCGIYVESEFNYLKQNDLKCYE
                     ERLVENTIIG"
     gene            complement(12035..14530)
                     /locus_tag="PC494_002718"
     CDS             complement(12035..14530)
                     /locus_tag="PC494_002718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HDF3913209.1"
                     /translation="MPENNNQLLEEITLLLNEGKVAINKAENQNLILILGGTGCGKST
                     AINYLAGCVMMEVEDEDTGISYIDCLDPVAEIGSGAVSQTLYPNIVNMRKPIEGMDAK
                     LCDTAGFSDNRGVAHDISAAVSLGEVFKNSASICAVIVLIPEADILDSRLTKVLDLFQ
                     QLNMCLHKENFKGSITFFISKSFLGRTEKQIYNVIKRKYEQLCENLDSNIEEKAWLFE
                     ELLKDNGKNIHLCKPLASDERDGLLKQVLELDEVKDKTSAFQYPISADARLVLDTLIK
                     EIQNNIVSSLEDYVKAYTEDFISIIGSITMIQEIAKYDEVVKVFKNWLESTTSLTIDR
                     FINVLAKQSGLFLQDSCMKLQNKIKGNLDIIDALSKYTEHGTGEILLPSVHMEFIIEK
                     ASKKIMEQNFIIIRKNLEKVLVSYEVQKQVFTLPNREKLMEVANKKDYVYSVSDFNSI
                     LTNVTVTQNEELEDSITRLSAYGEEGNEIIREFIGKYILNPFIVKTININDKKGIEIR
                     ALIPNLVISSVLEYFKNRKVDDNVSTFMFFAKDTIYMDDNLGMDFASEKNIILACNNL
                     DVGSNVKINVSGKSGELVDSSMYGKNGEDGRDSGNIYLYIKEEIRNYRLTLIANGGNG
                     SKGIDGKNGETGASGSNGADAGYTSYFHGQMFKGYFAKGTSGKKGEKGGAGGNAGRGG
                     NAGKKGNIYFISDSEEQKNRIINHCDITVKDGEAGPNGRPGSGGYGGSGGYHGYNTLS
                     FSPSGIDKTVYYTGYFTSWDYKLDSIIKYHIEFSGGSWNEGKTGPAREYAEYGDRGDN
                     GGFNAPNTKLSTAVSKVEENLIKEKYQGYCSEI"
     gene            complement(15167..15454)
                     /locus_tag="PC494_002719"
     CDS             complement(15167..15454)
                     /locus_tag="PC494_002719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3913210.1"
                     /translation="MRLNVTKQNTIEVENSRKEDVYFVIVDNVFFERQGDVFNSITNN
                     NLNNYDVKILPTDNVFLELKITSTKDLEPVFIVVEDRQYNHGSIMFKPVLV"
     gene            complement(15474..15749)
                     /locus_tag="PC494_002720"
     CDS             complement(15474..15749)
                     /locus_tag="PC494_002720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3913211.1"
                     /translation="MSLFVGGWSKFRAVEEEDLKVFNEAVGMLEGVGYEPLIVSTQVV
                     AGTNFKFICNATSVTNPPQNYLAEIVVFKPLPCDEHNATITSINIIK"
     gene            complement(16382..16561)
                     /locus_tag="PC494_002721"
     CDS             complement(16382..16561)
                     /locus_tag="PC494_002721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3913212.1"
                     /translation="MGKDRFEKVYSQGKINATEIWVDKETGVNYVFHYYGNAAGFTPL
                     LDREGKPVISPIVSK"
     gene            complement(16846..18312)
                     /locus_tag="PC494_002722"
     CDS             complement(16846..18312)
                     /locus_tag="PC494_002722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDF3913213.1"
                     /translation="MKRKPQYLIIFEHIIQQIYTGKITIGDRLDSIKSMSEEYMVSKN
                     TIKTVIKMLSEKGFIETKAGSRPVLIQSTSKQSIESDLLYEKILQISEIYKIFSLIFP
                     SIAMYNIKRFTSKDFEELNEIIDCMEKNSSNYLVFKEQRLKYINKLISKTNNFLIHHF
                     CEIIQHDVIISQLAYNFDNLDNCCIDFFRNKYIEQVRKTYLYGLDGNLIEFKKLLTYM
                     YKACRESILKIVENRAPQSIDTSSFNSVTLEKCYLYDLIVSDVICQIFEGNIKIGDCL
                     PSITSIINRYNVSLPTVRSAYNELNELGIAKTINGKGTYVTLFSEYDDDYINTEEGAK
                     RLSLLLDAMEFVTITLEDVVLLLGNKMDLIAVDKIETHLRYLQNNCEECKVYPDFVLL
                     CKIVDYTQIYVLQETFLHLKQYMIFGIYLERFFHEEYNEILKTRFDVCFEILRYLKKG
                     DVERFAESFSNIFKESLQYLKKVISSLNVDMRVKLDIL"
BASE COUNT         6210 a         3291 c         2055 g         7186 t
ORIGIN      
        1 ttatatataa tattaaaact ctttattttt taatatatat ttttctttta atatatctct
       61 tttatatctc tttaattttc ttcttctata tcagagccaa agggaatcca tgcattacca
      121 aactctttat ctttaaataa ataagctaat ccagttattt gcttcaatct aagaatttca
      181 tcaacttcca tacccaggtg ctttgatatc cattcatcag attttccaat ttcacaaagt
      241 tcagttataa ttttactcat taaatccaca ttatgagaac ctcttgcacg attgtgtcga
      301 atagtacttg ccattctttc atcaagagat ttatcaatta ctgaaacagg aagaagtccg
      361 ttttctctat catatatatc ctcattttca agcattactc tatatctatg aaaaccatct
      421 acaataatat acttatcctt ttcctcatta taataacaga caattggcat tgtataccca
      481 tcttctttta tacttttata caacaactgc atttctggtg gggctactgc atttggatta
      541 tagtcgttag attctatctt ttcgattggc actgcgatga ttccatatac aggactttta
      601 tattccatag catcttaact cctatctaat gaattttttc atatttcttc ttaatatatt
      661 ccgttctaat tctctgttct tttgtaggac caaatcccat aaatctacac atatggtcat
      721 tttttaaaat acaataacac attcttttcc aacttggtat atctttggta aatttaatat
      781 catccgtatc atcaggtata tcatccaaaa atatgactct actcttttta tcttttgtat
      841 gatttgaaac tccatttaat tctattttat aaccttttct caacaattca cgtataacta
      901 tttctgacaa accaccacct gtattctgcc aaaactcaat agatgttgaa aattttttaa
      961 tatagctatt ccttatattt tcaggtaagg tatcaagcaa aaaatatgtg aaacttttcc
     1021 atgtgtgtcc atatggcaat ttaacactac gatatcccat agcttttgtt ttgccataaa
     1081 tagaagtaaa attaactcct tgtactctag caaccaattt cacccataca tctgggtcca
     1141 atattctgta taaatttaaa ctctcttttg ctgaatcatt aaaaggtgat gccactctca
     1201 tttttcttgg agctactcca gctttataga ataagtcata aattttatta tagtcatagt
     1261 caaatttata gtgtgctaac catatatctt ctatttccca atcatatata ggagatgccg
     1321 tccagacatt tttaaattcc ttagttatcc agcactttcc tttatatcca tgctgtttat
     1381 tcacaataga acaataacgt tgtagagatt ctgctgctcg tgttcctaat aagcaaacaa
     1441 cttttgcacc ttcatgtata tctctaatcc atctaccaaa ttgttttgcc aaactttctt
     1501 gtctcatttt atatttataa taagtaaaag gattattttt ttgatttatt atgtattctt
     1561 tgactggcat ttcccttacc cataactctt ctttctcatc atcccatgga taccaataca
     1621 tttcataatt tcctacagca gttcttgtag ccattggtaa acacacccaa tatggttcaa
     1681 tatcttcaat attatcttca aatacttttt caacatattc agtagtcaaa ctatattgag
     1741 cctcaaaatc ttgatgaaat actcctattt tggaacttat attattcttt ctcttataat
     1801 ccaaaactaa atttagcagt aaaccactat cttttcctcc gctaaaagat acatagatat
     1861 aatcaaattc attaaaaaga taagaaagtc tttcttgaaa agcttcaaat acatcggatt
     1921 ctaaatatct cttatccatt tgaattatcc cctttcaatt agaagtttat aaaaccttac
     1981 aatgcaatat tattatgctt ttttagcagt aatcagcata aattatacat tatttaaata
     2041 cacaaatcca actaaataca tataattata atgtaattat acttttgtat tataaactat
     2101 attttatcat tattttacat ttttttccaa tatatataat tatcatattt ttctattagc
     2161 taaaactaat taccttatat ttttacgtat tggtataata atacataaaa acttgaataa
     2221 tgcataaaaa cttgacatac tgttgtcata attactttgc tataattaaa agtaaaaatg
     2281 gaggtaaatt ctaatgtatg aacgtatgct tgataaaagc aataaaccct gtttgtctca
     2341 aataatagaa tatataggta aagatggata tgcacgattg tgtaagttgg aaacttactt
     2401 gaaaactcaa tataatttat caagagaact tcgatttcct tttggaaaca attatggttg
     2461 gggttacaaa tatagccata aatcttttca tttattttat gctttttttg aaaaaggtgc
     2521 atttactgtt ctgattcaga taggtgacaa gcaagttcca gcagtagaaa aaacgttggt
     2581 agctttgaca ccaaaagcta aagaactctg ggtcactcgt tatccttgtg gcaataatgg
     2641 aggctggatt aagtatcgta ttttagaaga tgcagactta cttgatatta ttcaatatat
     2701 aagagcaaaa aaatctccac ctaaacaaaa ttaactttta ttttttgtga tttaaatata
     2761 gtgtatataa attccattct ttccatataa aaaaaataat ataaaaaata tctattagta
     2821 taacttattt agtatgtctt attctacttt ttacagataa ttaaaaagtt ttatcataaa
     2881 taaatcataa ctagacatcc tagtaaatca aaattaattt attctttttt attagaattt
     2941 ttgataacag tccctataca tatgccaatt atcattccaa aaattagacc ataacacatt
     3001 gtgataccta catttccttt agaaatacct atagcacaac ctatagccat tccaagtatc
     3061 atgcctataa acatacatat aataactaaa ttgttgtttt tattcatagt ttttctccat
     3121 tcaatatatt ttaaattgcc tagctcgcct tcttagctta aaacaaagaa atataaatta
     3181 actttctttc attctaatat ctgcttgtat aaatgtcaaa caacacattt cttgtcataa
     3241 cctcctcttt ttgaagtaag tacaatctcc cagacgcaat aatatcaatt tcctaaaacc
     3301 atttaagtaa cttttatatt tacataatat ttacaatcat aaactatatt gttattcatt
     3361 tatacatcat aaacactccc tcctaatcat tattatactt aaaataatgt tcatttataa
     3421 taatatatct aacgcacttt aattgaaaaa actaaaactt tgcctttcat tcccatatat
     3481 aaataagtat actttttgat gctctattac aaatcaacta aattaattga tataaattat
     3541 cattttctgt tgaaaatacc attcgaacat gctatactta attgcataaa tggtaataaa
     3601 tgtcatatga ttttacaaat ctattaataa caattattac ttttactgta ttctaaagtt
     3661 tttggactaa atatcaagaa ctttctaaaa tacaaagtac aaaaaattta tataagttat
     3721 aaatttatat gaactagata agctcaaaca atatgttatg tataaactgt gtagtattcg
     3781 gttataaatt tatataaatt atataagcta gataaagtat tacctcaact atataagcta
     3841 catatataaa ttacatacat aagctatata agaattattt caactatata aactacgcat
     3901 gtaaaattca tgtaaattta ctaatataaa tcaaataaaa ttactaaact ctctaaacta
     3961 attttgtaaa acatactcta tttttaacat ttgttacctt atacataagt acaaacaaaa
     4021 tctaactaaa tgaaaggata atgtaaaatg aatattttaa aaatgaaaaa aacagggata
     4081 tttttaggag gagtactttt tggtactgta ggtgttaaga tactttcaag tgattgtgtt
     4141 aaaaaaactt gcactcgtgc aacagcagga gcattgaaag ttaaagattc tgttcttgaa
     4201 acaactacga aaattcaaga aaatgtagaa gatattttag ctgaagcaaa agaaatcaac
     4261 gagcaagaag acttatctac atctaaggta aacgttgtac aagatactct taaatgcgaa
     4321 caagaagttc ttaaaactga aactataaaa actgtagaag atactaattc taatagcatt
     4381 aaatgtgaag aaatcaaaga taacgtaatt gaagaaaaaa atagtacttg tacaacagaa
     4441 taaatttaat gattattatg attaataata tcaggaggaa gtaaattgaa tttttatata
     4501 aaacacgaaa taagaggtcg tatacgcttt gacttacaac ttggcaaatt aaacaacaag
     4561 cagtccgata ctctcttata ttatttaact tctataaatg gtattaccaa agcaaaagtt
     4621 tacgatagaa ctggtgatgc agtcatttat tacactggtg aaagagaata cataataaga
     4681 gaaatcacta aattcagttt taacaatagc aaaatagaaa acctagttcc tgaacatacc
     4741 agcagggaat taaacaatta ttatagagac aaattagcaa ataaactgct agtcaaaagt
     4801 atctccaaaa tattttttcc aaagtcctta agattttttt taattggact tcattctata
     4861 aaatatttta aaaaaggtct ctcttccctg ctaaataaaa aaatagaagt ttctgtttta
     4921 gatgccactg ctataggtat ttctattttt agaaaagata tcaatacggc tggttcagtt
     4981 atgtttcttc ttggtatcgg tgaactatta gaagaatgga ctagaaaaaa atctatagac
     5041 gacttggctc aaagtatgtc actaaacatt gaaaaagtat ggttaagaaa aggtgacact
     5101 gaaatcttaa ttccaatttc agagataaag gaaggagatt tagtaagtgt aactatggga
     5161 aatatgattc cattggatgg agttatagta tcaggagaaa caatggtcaa tcaggcatca
     5221 cttacaggtg aatcccttgc agttaacaaa aaagaaggct cttacatata tgctggaact
     5281 gtaatagagc aaggcaatat tgttatgtgc gtcaaggaaa aagctggtac tactagattc
     5341 cagaaaatag taactatgat tgaggaatct gaaaaactaa aatcttctgt agagagtaaa
     5401 tttgaacatc tagcagatac attagttcca tacagctttt taggaagtat attaacctat
     5461 gcaattacta gaaaccctat aaaatcactc tctatattaa tggtagattt ctcttgtgca
     5521 ttaaaactct ctatccctat ttcagtacta tcagccatga gagaatgtaa caataacaac
     5581 attactgtaa aaggtggaaa atttcttgaa ggtgttgcat gtgcagatac tattgtattt
     5641 gataagacag gcacattaac aaaagctcaa ccaactgttt cagatataat tacattccaa
     5701 aattataata aggaggatat gttaagactt gcagcttgct tagaagaaca cttcccacac
     5761 tccatagcaa atgcagtagt ttatgaagct gaaaaacaag ggcttagtca caaagaaatg
     5821 catacagaag tagaatatat tattgctcat ggcatttcaa caaaagttga tgataaaaag
     5881 gttgtaatag gtagcaaaca ttttgtattt gaagatgaga agtgtactat cccagacggt
     5941 gaggaggata agtacaataa tctatcagat gagtattcac acctatttat ggcaatatca
     6001 ggtaaattat cagcagttat ttgcataaat gaccctttac gaaaagaagc aaaatatgta
     6061 atttcaaatt taagagaatg cggaataaaa aagattgtga tgatgactgg agatagcgaa
     6121 aaaacagcta aatctatagc aagtaaagtt ggtgttgatg aatattattc agaagtctta
     6181 ccagaagaca aagccaattt tgttaaaagt gaaaaactca aaggtcgcaa agtaattatg
     6241 attggtgatg gaatcaatga ttctcctgct atttcagaat cagatgtcgg aattgcaatg
     6301 agtgaaggtg ctgaaatagc aagagagatt tcagatatta ccatatcagc agataatttg
     6361 aataatttaa tcgttttaaa gcagattagt aataagctta tgaaaagagt tgatttaagt
     6421 tctaagttta ttatcggctt taatttaggt ttgattttac ttggtgtagg tggatttgtt
     6481 agaccaagta catctgcctt tttacacaac gcatctactg tcggaataag tttaaacagt
     6541 atgacaaatt tattggaaaa caccaatact tataactacc attaatctcc attacataaa
     6601 acatatgata taaaaaattt ataattcatc tttttaaaaa aatatgtctt aaaattagct
     6661 tttttctaat caaaattata taaagcatac tttacaaatt ttaaactcaa cttatttcta
     6721 ttttttacaa aaaaggagat gattcaaatt ttcattttga aacatcccct tttgtaaatt
     6781 tctttaaaat ttatatatta attatatttt caaccaataa ttgtattttc aaccaatctt
     6841 tcttcatagc attttaaatc attttgcttt agataattaa attcagactc tacataaata
     6901 ccacagccta ccaattcaat tgtcaaatta ggtatatttt cctttagtat actagtctgc
     6961 tcataaataa ttctttccaa taaatcaact tgtaatatag aaaaatgctt cataatctcc
     7021 ccatcactat ctatatcttt cttgatttca taccaactct ttgacaaaat tcccttcaaa
     7081 tcaatatacc ctagactcct caatatatct atactatcgc tccatgcata cttactaggt
     7141 ttatcaaagt atgactctag tttcttcttc tgctcatttg taagtgaatc ataagaaagc
     7201 ttcctattaa aatgtgcctt caaagaaatc ttagccatag aatatggact tctaccagag
     7261 tttaatcctg catttttgaa cttttcaatt cctttatctt ctactgaaga ccatattgag
     7321 tttattgaat ctgaatcatt gtatttaaca tcaagaccat gtgtaatatt tatatagttt
     7381 tgtggaaata catattgata atagacatct tttttatcat catatagaga gaagtatcca
     7441 ctatcatata aatgaatatg cacctttact tttaaactat cctctaaaat atttcgtcta
     7501 aggttcggga tatttgcata catggttaca tattttatgg catcaaagtt tttatttaat
     7561 ggaacttcaa aactaatttc atctcctgtc aaaagctttt tcacttcttc ttcattacaa
     7621 tcatatagag aatatgtatt ttcaaatccc acacgtgatt tcccatctaa actgcctgtt
     7681 aatgctacct tcaaaatatg gttatctgtt ttttgccatt ggtaagcatc ttggtcaaga
     7741 aactctctaa tctgtctatt ttgctctttc gcctgattta taacctcgtt ttcatcttct
     7801 gtaatcccta catggcatct atttaatata tttactatat tgcttccaaa tgggaatgtc
     7861 catagttgaa aagctgctgc ctcaacctga cacaagtatc taacctgatt taattcaatt
     7921 tgatggataa gttttttctg atattcattc atctgattac cactatctga catttgataa
     7981 atcaattctc ccattgcaag attatctttt ttcttatcaa tcttatcagt aatgataatt
     8041 tgagtttcca tcatatcctg tactttttta aatattatag aaatctcctc tgaattttcc
     8101 atttttaagc ttccaaactt cgtgcttaat tcagttaaaa cttccttcat ctttaattta
     8161 cttatctcat tttcaaaaat atcttgattt ttaactgtac tatcgaattt ttctacaaat
     8221 ggtataacag attctttcaa agttttatct ttaaattcca ccatttgagt attcaattca
     8281 tctaatttct taatattatt ttctttatct ttaattgcct ctttaactac ctctatttta
     8341 ctctcaaaac tagattttac attaagacaa ttattaacac cactaatcgc agtatttata
     8401 agagaacaag cagaacttcc aatactcaat gcatttttaa ttttagatgt cttttgctgt
     8461 ctttcaatag cttgtttact tttctctagt gcagctaact tatctttttg ctgtttatta
     8521 ttgtaatttg cctccaacat acctatttct tttttctgga tttttgtgta aatttcctta
     8581 tactcgcttt cacttaaccc ctcttttgct ctttgaatat cgtcagcttt gtctgcatag
     8641 ttatcatcat ctatagactt aactataatc tccttaattt ggtcaaattt agttcttctt
     8701 tcttcatcaa cacctgccaa attataagtc attttatcta aagcattttt tctatcttca
     8761 cttagctgtt ctccaagtac aaatctcata ccatcagaat ccaatttaaa atctgaaaaa
     8821 ttaaccatcc tgttagtcca tttgtattcc tcttctttag atgaaagatt ttccttcaaa
     8881 gattttgcac tgtcaaatgc ccctagacaa gcttgaccaa caccactaaa tgcagtcagt
     8941 aaactcaatg cgctttgtat tccagaaaga attaactgtg ttttcatttg ttcctcaagt
     9001 tttgcctgtt tcttttttag ttcctctatg tcttcttgtt catcttcttt catctttata
     9061 atttcttgaa tcaacaggtt catttttgca ttaacagaaa gcattttatt ctcaagttca
     9121 ttttttaaaa cctctatttg ttgatttcca gattcaattt gagttaggat actttcctta
     9181 tatgtattga aatatccttc ttttaactca tctttcttcc cttgttccaa ttctcttaag
     9241 gtcttatcca gataatctgt caaagaacga atatctgtaa cacgatttcc tccaatttca
     9301 ctttcttcaa tcatctgcac ataaaatgct gtcttctgct caagtgcaaa taaaatcata
     9361 ctccattcgc taaaattctg attttttcct acaaaagatt ctattctatc agactgcatc
     9421 aatttattta taaggtattc atagatttcc tttgcttctt tataaaattc tttctttgta
     9481 ttcatatcat ccagagaaag tactgcttta tttttcttct caaaactata gtacttctga
     9541 agtatttctc tatttaattg catctctatt ttctcaactg catgaaaaat ttcataaata
     9601 tgtgaaagtt ctaaaatatc agcttctaaa attcctactg cacacaacag tctaagattt
     9661 ctataacctt taattccaga aaaaccaaat ctctcgaaaa attcatagaa gaatgtatct
     9721 attgacaaag aatactcctg ctttaacaat tccttttctt ttagtgcatc tccagagtga
     9781 ccagcttttc cctctgctcc ggctgaacct gaatcttcac gtttgctaat tgtccagtcc
     9841 ttatgttctt cataaagagt atttaatttc tctccatcat ctgctgcttg cttctgattt
     9901 aaagcatgat taaacacata tctatcaaaa taatagtagt ttctatcact attatccatt
     9961 ggaggagagg tacctatata tcttattgtt tcttcatata tacctctaat tccaccaaga
    10021 cctcctgcac caccagctcc tccagagcct ccttttcctg ctaaaccatg atttccatct
    10081 tttttactta tagcactttt taataaagga gcttttccaa ggagataaac ctgtccagac
    10141 ttgcttccaa gacctgcatt tccaccatta cctcctgtgc ctccagttcc accttgtttt
    10201 cctttttctg cttttacaac atagtatttt gtacctttaa cattagcaaa ttcttttgac
    10261 tcttttttag aacctatttt agcatttgcc ccagcttctc cagttatccc tgtatctcct
    10321 ttttttccat cttgtccatt tccaccacgt ccaccatcta cgtaaagttt aagttctcct
    10381 cttttttcta tttctttaaa agataatatg atatcacctg aagtacctgc attattgcca
    10441 tttcttccat tcattccgtc gtaaatagaa ctttctccaa ccaatttttc tgcatcctta
    10501 ccagatacgt tgattgaata agtcccttct ggtatatgta atttttctgt aagtagtaca
    10561 atattcttac ctgagaagac ttctttctcc atattacagt caattttcaa ctcacaatct
    10621 ccatacatat atatagatga caaaatatta agttgataac cagatattat tttagtcaaa
    10681 tccgataaat tcactttagg tataggaata tatatagaaa gtacattttc tttctcatat
    10741 gattttatat atgtacaact ttgaatcttc tctatcctat actctgcatc ttcaagcttt
    10801 ttggcttctt cttccctata ttcttcttct gctatccaat atttgatatc ttttaatgta
    10861 tcttctaaag tattttttag caatgatttt aacaactcac ttagaccaac aatatgagtc
    10921 tcactacagt aactatttaa ctctaaaaga agacgtgttt cttctaatat attcactttc
    10981 tgtacgccat caccatatga aagttcttgt acaaactcca taagctcttt catattatta
    11041 gtcctactac ataaatctgt atacatctta tctaattgaa tctttttatc ttttagacta
    11101 tttatagaag atagaatgga aatagaatct tccatacctt ttttaacact ttctatataa
    11161 ggaactaaaa gtttttctag gtctttatag gttacatcaa cagctttttg tatttctatt
    11221 ttacaagaag cagtaagcat caatcccaaa tctgtttttt caaatgtttc aggtagattt
    11281 ttcatttcat tcaacaactt ttctggctgt ttatctagtg gattacataa tttaatagat
    11341 acaccatctg ataatgctac atttaataag tacactaatt ccttataacc gtcgtaatct
    11401 ttctcttgac tatctaggtc ttcttttgct tttttcaata tatttcttat tttttcttct
    11461 gttacattac cgattagtgc tttaggtatt ttattgataa gaaagaagaa attttcttta
    11521 tactttgcat aatcaccaag catatctttc aaatttttgc ctgtttctat taataatgta
    11581 tgtctagagt ccagtaagga ttgatagtct aaaataacta ccatcccttt cacctttgaa
    11641 gatgtagaaa tagtttccct tacaagcata gcaccagcaa tcatatactc tgctccacgg
    11701 ttatcaaaaa aacctgggca atcacataat gaaaaatctc tatttgcaat atctacaact
    11761 tctggacata aagtcttaga atatacacca tttccaattt cgacagctga atcttttgca
    11821 gttatatata tttgtccagt ctcttcatcc gttttttctt ccatcacaca gccttttaaa
    11881 taatttatac aagtactctt tccaacgcct gaagcaccta ggaataacaa aattgacttt
    11941 tcttttaagt catattttct aagctcgtct cttccttctt ccaaaaggtt tacgatttca
    12001 ctataaagtt tatttgccat acatccatcc ctttctatat ttcggaacaa tagccttgat
    12061 atttttcttt aataagattc tcttctacct ttgaaacagc tgttgataac ttagtgtttg
    12121 gagcattaaa tcctccattg tctcctctat ctccatattc agcgtattct cttgctggtc
    12181 ctgttttacc ttcattccaa cttccaccac taaattctat atgatattta attatactat
    12241 ccaacttata atcccaactt gtaaaatatc ctgtatagta cacagtctta tctataccac
    12301 ttggagaaaa tgaaagtgta ttgtatccgt gatagccacc acttcctcca tatccacctg
    12361 aacctggtct accatttgga cctgcttctc catctttcac tgttatatca caatgattaa
    12421 ttattctatt tttttgttcc tctgaatctg aaatgaagta aatattacct ttcttaccag
    12481 catttccacc tcttccagca tttccaccag ctccaccttt ttcacctttt ttgccacttg
    12541 taccttttgc aaaataccct ttaaacatct gtccgtggaa ataacttgta taccctgcat
    12601 cagctccatt acttccagaa gctcctgttt caccattttt cccatctatt cctttagaac
    12661 catttcctcc atttgcaatc agtgttaaac gataatttct aatttcttct ttaatatata
    12721 agtaaatatt acctgaatct ctaccatctt caccattttt accatacata gaactatcta
    12781 caagttctcc gctctttcca cttacattaa tttttacatt actacctaca tcaagattgt
    12841 tacaagcaag aataatattt ttctctgatg caaagtccat tccaaggtta tcatccatat
    12901 aaatagtatc tttagcaaag aacataaatg tagaaacatt gtcatctact tttctatttt
    12961 tgaaatattc caatacactg ctaattacta agtttggaat taatgctctt atttcaatac
    13021 ctttcttatc attaatatta attgttttta ctataaatgg atttaaaatg tatttaccaa
    13081 taaattctct aattatctca ttaccttctt ctccatatgc acttaatctt gttatactgt
    13141 cttctaactc ttcattttgt gtaactgtaa catttgtcaa aattgaatta aaatcactta
    13201 cactatatac ataatccttt ttatttgcaa cttccattaa tttttctcta tttggtaatg
    13261 taaatacctg tttttgcact tcataagaaa ctaaaacttt ttctaaattc tttcttatta
    13321 taatgaagtt ttgttccatt atcttcttac ttgccttttc tataataaat tccatatgca
    13381 cagaaggtaa taaaatttcc ccagttccat gttctgtata tttacttaaa gcatcaatta
    13441 tatctaagtt tccttttatc ttattttgta atttcatgca actatcttgt aagaataagc
    13501 cactttgttt ggctaatacg ttgataaatc tgtctatagt aagacttgtt gtactttcca
    13561 accagttttt aaatactttt acaacctcat catattttgc tatttcttga atcattgtta
    13621 tacttccaat aatactgata aaatcttctg tatacgcctt aacataatct tctaggctag
    13681 atacgatatt gttttgaatt tcttttatca acgtatctaa aactaatctt gcatctgcac
    13741 taattggata ctggaatgct gatgtcttat ctttaacttc atctaattct agtacttgct
    13801 ttaataaacc gtccctctca tctgatgcaa gtggcttaca aagatgaata ttttttccat
    13861 tatcttttag caattcttca aataaccaag ctttttcctc tatattactg tctaaatttt
    13921 cgcataattg ttcatatttt ctttttataa cattatatat ttgtttttct gttcttccta
    13981 agaaactttt tgaaataaaa aaagttatac tacccttaaa attttcttta tgaagacaca
    14041 tatttaactg ttggaacagg tctagtactt ttgtaagtct agaatctaat atatctgctt
    14101 ctggtatcaa tacaattact gcacatatag atgcagaatt tttaaatact tcacctaatg
    14161 aaactgctgc gctaatatca tgggctactc ccctattgtc gctaaaacct gcagtatcac
    14221 ataattttgc atccattcct tctattggtt ttctcatatt tacaatgttc gggtataaag
    14281 tttgagaaac agctcctgaa ccaatctctg ccacagggtc taagcaatca atatatgata
    14341 taccagtatc ttcatcttcg acttccatca ttacacatcc tgcaagatag ttaattgcag
    14401 tacttttgcc acatcctgtc ccaccaagaa ttagaattaa attttgattt tcagccttat
    14461 ttattgctac ttttccttca tttaataaga gtgttatttc ttctaaaagt tgattgttat
    14521 tttctggcat ttattttccc ccttggttat atattttatt taaataaagt ttaatccctt
    14581 aagtagatta caaagttttt agactatatt taaatttgtt ttttattttt tatttttaat
    14641 aaatttgcat tttcactaaa tttgtatttt cactcaataa ttattcttct ttgtttatta
    14701 aaataactgt gttgtataat ataatcttta ccaacacagt tattctattt aatgcgctta
    14761 ttttattgta ttttatgtaa tacagttgtt ttttatatta tatgtccatt attttcctat
    14821 ggttattaca tatagatttt taattatatt tgtaccatta atttaaacat tcctatacta
    14881 ctgcttaagt tttacaccta taccagcttg aatattttat ttttatttgc ttaaatagtt
    14941 caactatact ggtttaaata ggttatcttt atttgcttaa atagttcaac tatactggtt
    15001 taaataggtt atctttattt gcttaaatta gttcaactat actggtttaa ataggttatc
    15061 tttatttgct taaattagtt caactatact ggtttaaata ggtttccttt agtttaaata
    15121 attcacctat acctacttga atagttcact tttatttgct taaattctat accaatactg
    15181 gcttaaacat tatactacca tgattgtatt gtctatcttc aactacaata aaaacaggtt
    15241 ctaaatcttt agtagatgtt atttttaatt ctaaaaaaac attatcagtt ggtaatattt
    15301 ttacatcata attatttaaa ttattattag tgatactatt aaatacatca ccttgacgtt
    15361 caaaaaaaac attatcaact attacaaaat aaacatcttc ttttctacta ttttcaacct
    15421 ctatagtatt ttgtttagtt acatttagtc tcatcttcca cctcctatta atattactta
    15481 attatattaa tacttgtaat tgttgcatta tgttcatcac aaggaagagg tttaaaaaca
    15541 actatctctg ctaaataatt ctgtggagga tttgtaactg aagtagcatt gcaaataaat
    15601 ttaaaatttg ttcctgctac aacttgagta gaaacaataa gtggttcata accaacccct
    15661 tctaacattc ctacagcttc attaaatact tttaaatctt cttcttcgac agctctgaat
    15721 tttgaccatc caccaacaaa aagactcata taaaaacctc ctttatatat atatttattt
    15781 atatatagta gtaccaattt tctcaatatt caatattttc tgtgtaactg gtcaatgaaa
    15841 atgcataact ggataaaaat acttataaaa taacttaact ttacatataa atagcttact
    15901 ttacatgtaa taagattatt ctacaatatg aaatacatct tgttttgaat atattctaaa
    15961 tacaataatg gatattttca attattatcc ttagaaaata tccattactt aacttgtttt
    16021 atttaaaatc acatagagac tttattattt tttttattgc atgaatagct atttcaggta
    16081 tcataaggtg atataccccc tccttgaaac cacaaaaaac atgacaaact ttacgaatct
    16141 tggcttaaaa aactacaggt acattcctta tttgtggatt ggagtagcca taacaagcaa
    16201 attttacaat ttttatgatg acaaaatcaa taaaatcgct tagtatataa cacgaaacac
    16261 tacttgttgc tattaagaat agttagatag gaagtatgca ttataccaat aaaggaatca
    16321 ataaagaaag ttaaaacatc cctacaaatc aaaaatctgt tacattttct atatttaaac
    16381 gttatttact tacaattgga gaaataacag gttttccttc tcggtcaagt aaaggcgtaa
    16441 atccggctgc atttccataa tagtggaata catagttcac acctgtttct ttatccaccc
    16501 aaatctccgt tgcatttatt tttccttgtg aatatacttt ttcaaatcta tcttttccca
    16561 ttttataatc ccccatattt ttgattggtc tataccttct tcacttaagt cgaaaaaata
    16621 cataacttat ttttttaatt ctaatatgaa cacgtaaaaa tgtcaaacag cttatttaat
    16681 ttcataactt catgttactg ttcgtaacct tgtttgttta cttacactac attacagcac
    16741 cattttaccc tttacatgat tgtattgcac acagcaaaaa tgcttacttt attggatttt
    16801 tcaactaaaa aaaggttttt ttctccacag aacatttact attttttata atatatctaa
    16861 ttttactctc atatcaacat ttaatgaaga tataaccttt ttcaaatatt gtaaagactc
    16921 cttaaaaata ttagaaaaag attctgcaaa tctctcaaca tctccttttt ttaaatacct
    16981 aagtatctca aaacatacat caaaacgtgt tttcaaaatt tcattatatt cttcatgaaa
    17041 aaatctctct aaatagattc caaatatcat atattgtttt aaatgcaaaa atgtttcctg
    17101 taatacataa atttgtgtat aatctactat cttacaaagt aaaacaaaat ctggataaac
    17161 cttacactct tcacaattat tttgtaagta ccttaaatga gtttctattt tatctacagc
    17221 tatcaaatcc attttatttc ctagtaaaag tactacatcc tcaagagtaa tcgtaacaaa
    17281 ctccatagca tccaaaagca aactcaacct tttagctcct tcttctgtat ttatataatc
    17341 atcatcatat tcagaaaaaa gtgttacata tgttcccttg ccattaattg ttttagcaat
    17401 tcccaattca tttagctcat tataggcact tctaactgtt ggaagtgata cattatatct
    17461 attaattatc gaagtaattg atggtagaca atctcctatt ttaatattgc cttcaaaaat
    17521 ttgacaaatt acatctgaaa caattaagtc atataaataa catttttcca acgttacaga
    17581 attaaaacta cttgtatcta tactttgtgg agcacgattt tctactattt taagtatgga
    17641 ttctctacaa gctttataca tatatgttaa tagtttttta aattcaatta gattcccgtc
    17701 caatccatat aagtaagttt ttcttacctg ctctatgtat ttattacgaa aaaagtctat
    17761 acaacaatta tccaagttat cgaaattata ggccaattgt gaaataatga catcatgctg
    17821 aataatctca caaaaatggt gaatcaggaa attatttgtt ttacttatta gtttatttat
    17881 atattttagc ctttgttctt taaagactaa ataattagaa ctattttttt ccatacaatc
    17941 gataatctcg tttaattctt caaagtcttt agatgtaaat cttttaatat tgtacatagc
    18001 aatagaagga aatattaaac taaaaatctt atatatttct gatatttgta aaatcttctc
    18061 atataataag tcagattcta ttgattgttt actcgtactc tggattaaaa ctggtctaga
    18121 accagctttt gtctctataa agcccttttc tgagagcatt tttattacag tttttatagt
    18181 attttttgat accatatatt cttctgacat gctttttata gaatcaagcc tatctccaat
    18241 agtaatttta ccagtataaa tttgttgaat tatatgctca aaaataatta aatattgtgg
    18301 ttttctcttc atatttttcc tcttcgataa attagattta ttgttttttg taaggtatat
    18361 ttacttttat ttaatagggc aaaatagttg cttatttttt cctcataatc tataattaat
    18421 ataaaccatt tatatatatg gtctaagttt tataatactg taatgcagta aaatagcata
    18481 ttgtagctat actacagcaa attaacatac cattgtagta tattaattgg aataatttta
    18541 agtacttcaa aattccagca aaacatatat gtgtttttga tattatgtat attcgttaat
    18601 agaatagcta tacttgtttt acataataaa ttatatgata cttgctatat gtaattacta
    18661 tatttaatac acataactat gatacttgct atatgtaatt actatattta atacacataa
    18721 ttattatact tactatatat aa
//
LOCUS       DAMKNB010000070        18724 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.072, whole genome shotgun sequence.
ACCESSION   DAMKNB010000070 DAMKNB010000000
VERSION     DAMKNB010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 18724)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18724)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18724
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.072"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            845..2515
                     /locus_tag="PC494_002723"
     CDS             845..2515
                     /locus_tag="PC494_002723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF and EAL domain-containing protein"
                     /protein_id="HDF3913214.1"
                     /translation="MREESNSLSLDHIEIFFELLSQSTEDYIFFWDINRNKFKISSAI
                     FDEFNLSKEIESDLVNCWSKIVYPDDVQIWKDDIQELLHGKKGEHNLEYRLINKYKEI
                     VWISCRGKVYVSDDPKTIFLVGRIKNIGEKNKFDSITGTWNREQFEHRMNYLIKEKIY
                     KNGAMFIMDIDNFKNINEKYGHSYGDKVLRAIATEVLEYLPKDVRLYRLDGDEFAFFY
                     PMCTKETIEKIYEKIQMYTNTQHEIESNKYYCTVTAGVAMYPEDGDNYLDLFKHADIA
                     LDIAKISGKNRIKFFSQELYENKLKVISMQQKLRECVENNFNDFELFFQPQVNAVTKE
                     VIGAEVLLRWHSSTYGEVSPVEFIPILEQSNLIIPVGKWIIKEAVKQCKEWHKINPDF
                     KISVNVSYIQLKEDFFRDFIVECLVEYQLRPEFLILELTENCWIPDINLLNDKFISLK
                     GIGVYIAIDDFGTGYSSLNYLKELSVNIIKIERSFVKNITYNSYEYTFLEYIIKLAHI
                     INLKVCVEGIESYEEYDIVKSLGVDIIQGFLFGRPVSASEFYKFQLSK"
     gene            complement(2637..3371)
                     /gene="pflA"
                     /locus_tag="PC494_002724"
     CDS             complement(2637..3371)
                     /gene="pflA"
                     /locus_tag="PC494_002724"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase-activating protein"
                     /protein_id="HDF3913215.1"
                     /translation="MIKGKIHSIETFGTVDGPGIRYILFFQGCPLRCKYCHNRDTWDI
                     KSGKEYTVDEIITDALKYTSFMKFSGGGITASGGESTLQPEFLSELFKKAKENDIHTC
                     LDTSGFVDIETIDPVLDNTDLVLLDLKHMVEEKSIDLTGVGMDKALKLARHLESRNIP
                     VWIRHVLVPGITDDIDNLEKLGQFVATLKNVERFELLPYHSMGIHKWESLGIDYELKD
                     VPDATKEDVQKASEIISKFGVKVYNS"
     gene            complement(3531..5762)
                     /gene="pflB"
                     /locus_tag="PC494_002725"
     CDS             complement(3531..5762)
                     /gene="pflB"
                     /locus_tag="PC494_002725"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HDF3913216.1"
                     /translation="MNAWQGFKTGRWTKEINVREFIQLNYSPYEGNDSFLAGATENTK
                     KLWDEAMVLFKKERENGGTLDVDTKTVSGIAAYAPGYLDKELETIVGLQTDAPLKRAV
                     MPYGGIKMVENSCEAFGYELDPEIKDIFTKYRKTHNQGVFDVYTPEMRAARKSGIITG
                     LPDAYGRGRIIGDYRRVALYGVDALIEDKNEQKKSLEVSCMDEEVIRLREEITEQISA
                     LNELKKMAESYGFDISKPATNSKEAVQWLYFGYLGAVKDQNGAAMSLGRTSTFLDIYF
                     ERDLKAGIVTEEELQEYMDHFVMKLRMVKFLRTPDYNNLFSGDPTWVTECIGGMGIDG
                     RTLVTKNSFRMLNTLYTLGPSPEPNLTVLWSTKLPQGFKDFCSKVSIDTSSVQYENDD
                     LMRAYWGDDYGIACCVSAMRIGKQMQFFGARVNLAKTLLYAINGGVDEKSGVQVGPRF
                     EPITSEYLDYDEVMSKFEPFTDWLATLYVNTLNVIHYMHDKYSYEALEMALHDRDIFR
                     TMACGMAGLSVCADSLSAIKHAKVKTIRNEQGIAVDFEIEGDYPKYGNNDDRVDSIAV
                     ELVESFMNKIRKNKTYRNSYPTQSILTITSNVVYGKKTGNTPDGRRAGAPFAPGANPM
                     HGRDTNGALASLSSVAKLPYEHAQDGISNTFSIVPAALGKDMTERINNLSAMMDGYFA
                     QNAHHLNVNVFDRATLEDAMEHPEEYPQLTIRVSGYAVNFIKLTKEQQLDVINRTFHG
                     KMA"
     gene            6055..7116
                     /locus_tag="PC494_002726"
     CDS             6055..7116
                     /locus_tag="PC494_002726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="calcium/sodium antiporter"
                     /protein_id="HDF3913217.1"
                     /translation="MEKRKSIHLHKLNIYLIGGGDRLFITVVLFLVGFLLITKGADIF
                     INCTVEIGKKTNISEIILGATIVSFATTLPEFTVSLLASIDGHTTMSLGNAVGSIICN
                     TGLALGLVVFISPFNVDKKMFFSKSLLLIVSVIVLILLSLDGVITRGDSLLLIIILIF
                     YMVNNYRSVVGKSDTKNRNIKNNTIKDISTKKGKNYRGFSVLEIVKILLLFATGLIMM
                     IIGSQILIESGVIIASFLNIPQGIVSLTIIALGTSLPEIVSSITAIRKNHHEISVGNI
                     LGANILNIVSVIAVSAIPNNIPILSQNRQLDIPFMILLLLIVIIPTLKSNKLSRIQGI
                     LMLFTYFLYISILYFMYII"
     gene            7207..8820
                     /locus_tag="PC494_002727"
     CDS             7207..8820
                     /locus_tag="PC494_002727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HDF3913218.1"
                     /translation="MNITKFEDLPISEGIKKAIAEMGFEEPSPIQAQSIPAILSGKDV
                     IGQAQTGTGKTAAFSIPILETIDPNNRSLQAVVLCPTRELAIQVSTEIRKLAKYSHGI
                     KTLPIYGGQPIDRQIKSLKSGVQVVIGTPGRTIDHINRKTLKMDNVKMIILDEADEML
                     DMGFREDIEMILSKIPEERQTTFFSATMPRGILELTKRYQKDPEHIKVVRKELTVSNT
                     KQYYIETRSSNKLEVLCRLVDVYDPKLSVVFCNTKRKADELVGDLQARGYFADALHGD
                     LKQTQRDIVMDKFRNGTIDILVATDVAARGIDVDDVECVFNYDLPQDEEYYVHRIGRT
                     GRAGREGMSFTFVFGKEMRKMKDIERYTKSKLIKHNIPTITDVEEKKVGTFFAQVKQT
                     IEEGHLTKQLQWLEGFCNDEDYAMVDIAAALVKLSLGEEMKEEIIEEKPRRERGDRKG
                     GTGAKDGMIRLFINIGRNQRVQAKDIVGAIAGEVGIPGKVVGTIDIYDKYTFVEIPKK
                     DAKTVIEKMKDIKIKGNKINIEKANKKKK"
     gene            9095..11080
                     /locus_tag="PC494_002728"
     CDS             9095..11080
                     /locus_tag="PC494_002728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HDF3913219.1"
                     /translation="MSMTYMDPRVFLILEMVLEEDTNTLEQFSNVLGVSTRTIRNYIN
                     QINRELKGGIAKIVKNEKGTYSIRIEDESKLIEIVNFNRGKLSNFINLNSPDERINYV
                     LDILTMTNNPITIDDLAEEICIGRTTLIKDLKKADRILAEYDLELKRKPNIGMILVGE
                     EMDIRLLILDRLYENYIDVLENVNQINLVKDYDIECLRDELKKLFKKEELYITEQVLR
                     DVERYIIMSVLRNLNGYKFEKIDKRFEVIRCSDEYTLGLKLKALLEKIFNIVLNEKET
                     IFLTMPLIGRKAPSTKLALSSIKINDSVKEVVDEVTSFLLETSGIDFKEDKKLIENLE
                     YHLYFALNRMRFNIRVKNPLLQEIKERYTFPYSVAKIAAMIIEEKFDLKICDHEIGYI
                     ALHFGSYFEKNSRKVLNVNRVAVVCGTGLGTAQLIRIKIGKILGESVEVNTFSDIEAK
                     ANLDLLKYYDLVFTTVDFKTDLDVPIFRVNALFNEESIKKEIENAILLKNSINLKSIK
                     KIEKNIPFIGKLIEEDKFFILNKSTFMENLEDMLEKLVHKGIIDIEFKKKVLKREKKS
                     STALDNYIALPHSVNTNGENLYLAFGILEKPVIWDTKEIRIIILMIIPDKNVDSTDLI
                     IKSYEEVLEVGRDKKMVEELAKVKSFDEFYKIITKRR"
     gene            11085..11519
                     /locus_tag="PC494_002729"
     CDS             11085..11519
                     /locus_tag="PC494_002729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator GutM"
                     /protein_id="HDF3913220.1"
                     /translation="MDPVIFIIASLITVYLLNIFLGYLQLKDFNKNYIELKRKGRVAI
                     GRKKGRISSGTIVLILINDDGVIVETRKMQGVTVLARVKSFEGLVGKSLEYIEKSDLT
                     VYNKLLKKAILDAVKQYITFEKNKCEDTNNLSTDEECRMEVV"
     gene            11548..12108
                     /gene="srlA"
                     /locus_tag="PC494_002730"
     CDS             11548..12108
                     /gene="srlA"
                     /locus_tag="PC494_002730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418408.1"
                     /note="catalyzes the phosphorylation of incoming sugar
                     substrates along with their translocation across the cell
                     membrane; the IIC domain forms the PTS system
                     translocation channel and contains the specific
                     substrate-binding site; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIC"
                     /protein_id="HDF3913221.1"
                     /translation="MTQFFQVLASGADSFMNLFRAGGQQFVGFVTDIVPLLVALLVTM
                     NAIINFIGTDRVERLAKKCSANIFTRYLILPVLGTFVFANPMTLSLGRFLPEKFKPSY
                     FAAASFSCHTMNGLFPHINPGELFIYLGIANGITTLGFSTADLAVRYLLVGIVANFIK
                     GVVTDYTTKFVEKQQGIALNSDIKIG"
     gene            12172..12540
                     /locus_tag="PC494_002731"
     CDS             12172..12540
                     /locus_tag="PC494_002731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sorbose transporter subunit IIB"
                     /protein_id="HDF3913222.1"
                     /translation="MAFNKVKIVKGSGGWGGPLIIEPTEKKNKVVYVTGGAKPETAVK
                     IAELTGCELIDGFSQGVKDDEIACVIINCGGTLRCGIYPQKKIPTINIMKTGKSGPLA
                     MFIKEDIYVSGVKPTNVEQL"
     gene            12565..13131
                     /locus_tag="PC494_002732"
     CDS             12565..13131
                     /locus_tag="PC494_002732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003374365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIB"
                     /protein_id="HDF3913223.1"
                     /translation="MAYDTKKKISEQSQGIVAKIGIALGNVTSTLFQAGRDTIDTLIH
                     TILPFMAFVAVLIGIINQSGIGNWVANLLTPLIGNVGGLVVLSIICSFPLLSPFLGPG
                     AVIAQIVGVLVGTEIGKGNIPPSLALPALFAINSQAACDFIPVGLGLAEAEPDTVQVG
                     VPSVLYSRFLTGAPTVLLAWLASFGLYK"
     gene            13172..13537
                     /locus_tag="PC494_002733"
     CDS             13172..13537
                     /locus_tag="PC494_002733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HDF3913224.1"
                     /translation="MELIYSTQINKIGDNANEFLQHNMFVTFKDNAPQELENYCYIHS
                     ENNLVKEILTDDVLSINNVDYKITSVGELVNQNLSELGHITFKFTGEKDGAIGGTLYL
                     EEKEIAPIGVGTILKIIRK"
     gene            13638..14411
                     /gene="srlD"
                     /locus_tag="PC494_002734"
     CDS             13638..14411
                     /gene="srlD"
                     /locus_tag="PC494_002734"
                     /EC_number="1.1.1.140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sorbitol-6-phosphate dehydrogenase"
                     /protein_id="HDF3913225.1"
                     /translation="MRKVALVVGGGRSLGEYLSKHLAKVGYDVAIADLNEDNAKKVAE
                     EIKTEFGCKSVGYSCNAIDERQVISTVKAIENDFDRIDLLVYNAGVAVSKKITDFGYK
                     DFKFIVDVNLNGYFLFAREVSKVMIAKGIEGRIIQINSKSGRVGSKHNSGYSAGKFAG
                     VGLTQSLALDLAEHKITVNALMLGNLLDSDMFESLIPQYAVKLGIPESEVKQVYIDKV
                     PLKRGCRFIDVANMLTFYASKEAEYCTGQSINITGGQVM"
     gene            14759..17029
                     /locus_tag="PC494_002735"
     CDS             14759..17029
                     /locus_tag="PC494_002735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-dependent oxidoreductase"
                     /protein_id="HDF3913226.1"
                     /translation="MDIIKKLSHGCTLDCHDCCKFNVYTKGNNVVKIEGDKNHPYTKG
                     FICKKGMAHLDRLNHKDRIKTPMLKVDGVWKEISFDKAIEIMAEKLTYYKEKYTSKSV
                     MHYDQYGSGSVLKYIGDIFFNFYGGVSRHKGGPCWSAGMHAQKYDFGVAKSHAIEDML
                     NSKSIFVWGKNPAYTTIHTMQIIKKAKEKGIKIVVIDPIYTKTAQIADKYVQVNPGTD
                     GALAIAMAKIIVEDKLYDEEYINSYVIGFEEYKKYLSSLELSFLIDECGVKENDIREL
                     VDLYTNKYSSINVGYGLQKYKNGGNTIRAIDALGAITGQIGFSGGGVNYANKVYPSVI
                     NSDPYNSQSYGEDREFYVSNISKFIEESLKNTSNKVNYASDELDMALHKVNYISDELD
                     TTSNKVNYVSDELDITSNKVNYVSDELDMTSNKVNYVLDELDITSNKIDYISNELYNL
                     SNKSIKDNIPIKMAVITKSNMLNQLPDLVELERVFSKIEFKVCFDMFITDTATLCDMF
                     IPCTNTLESEDIIYSSMTNPYITYNERAVKPAHKLMDEYYFFMELAKKMGLNDYPFVE
                     KRTYLEKVIEPLKRFDKNLDIEKLKNNYFTIHNPVAWEDKKFETPSGKYELYSESIKN
                     LGISPTPVYISNKYKEIEDKNISFRLLTNHHADTLFSQHFMDKKSIAQAYINRRMAKK
                     VGIEDKDIVILRSKKAKINVQINIDDGVGNYIVKMYVGWWKKHGNPNSLTDTGISDFG
                     GQVTYNESMVEIIRQN"
     gene            17117..17452
                     /gene="spoIIAA"
                     /locus_tag="PC494_002736"
     CDS             17117..17452
                     /gene="spoIIAA"
                     /locus_tag="PC494_002736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anti-sigma F factor antagonist"
                     /protein_id="HDF3913227.1"
                     /translation="MVNYSLEHKNLYIEFMCSELDHHVANEIREEIDNLLSVNQVKNV
                     VFNFENINFMDSSGIGVIIGRYKKISNEGGRVSVINISSRVKKIFDLSGLNKIIGIYD
                     TYEEALSSL"
     gene            17466..17894
                     /locus_tag="PC494_002737"
     CDS             17466..17894
                     /locus_tag="PC494_002737"
                     /EC_number="2.7.11.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anti-sigma F factor"
                     /protein_id="HDF3913228.1"
                     /translation="MNNIMEVKFSAISENESLARVIVASFAAKLDPTVDELVDIKTAV
                     SEAVTNAIIHGYEEDSSKFVFLRCEIEGNTIKIIVEDEGYGIENVEKAMEPLYTSKPE
                     LDRSGMGFTVMKSFMDDVEVSSVKDNGTRIEMTKKINVPK"
     gene            17917..18681
                     /gene="sigF"
                     /locus_tag="PC494_002738"
     CDS             17917..18681
                     /gene="sigF"
                     /locus_tag="PC494_002738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sporulation sigma factor SigF"
                     /protein_id="HDF3913229.1"
                     /translation="MEVTVAREEKKPLLSHEETLELIEKVQNGDEEAKEILISSNLGL
                     VRSVVSRFLNIGYDREDLFQLGSIGLIKSIYKFDPKFNVKFSTYAVPMILGEIKRYLR
                     DDGMIKVSRSLKQIAVKAKMESEALTKKLGREPSIEELAKAIDVEKEDLVMAMEANFN
                     VEYLQGVIHEEEGSPICLIDKISMKGESEEEKVVDNILLKDILGRLDKRERQIIVLRY
                     FEDMTQSEIGEMLNISQVQVSRIEKKVLSKLKEYIS"
BASE COUNT         7307 a         2112 c         3227 g         6078 t
ORIGIN      
        1 aatggaaact atggatgtaa taattaaaat aaaaaatatt attttatatt tataaacatt
       61 gacattctaa ttttgtagtg taatcgtatt ttttattaat tcttacaaaa tcaatgaaaa
      121 taagtatatc cattttaaag tacataaatt taaaaatcca gaaaaatata cttaaattat
      181 gtaagtaaaa gaggggttga atcagttgaa aatgtaatat tagtaaatag tacatcaatc
      241 ctatataccc tgtaagcaac tctattttca tgtactaaaa atgtacctat tttattaact
      301 gaaaagaata aattaaatgt aagtacataa gaagatagaa aaaattaaaa acaaaaaata
      361 tttatataaa taaatataaa aaatgatata atccctatta aaaaatttat agatgatgaa
      421 gaaatatcaa aatcttatat tataggaaga gacacttctt tgccaaaatc tatagaaaag
      481 caataccaaa tccaaagaga ataggcgaag aaaaaaataa aataaattca agagtaatag
      541 aaaagtttta tagaataaag aactgataac tctttatata acgaaaaata gaattttaag
      601 agaaaatgat ttaataaatg atttaacatg gtgttttagc aggtaaaaat aaatcaccag
      661 taatgattat agaaaaatta ctttatgaat ctcaaaaaac ttagttaaga gtaagagatt
      721 tgataagata actaaagttg gggaaatgtg tttgatgaga caaaaaatta gtaaaatagt
      781 ataatctaaa taaggatatt ttgttgatta aactacacta atagtaatat tgtaggggga
      841 aaagatgaga gaagaatcga actctttaag tttagaccat atagaaattt tctttgaact
      901 tttatctcaa agtacagaag attatatatt tttttgggat ataaatagga ataaatttaa
      961 aatttcttca gcaatttttg atgaatttaa cttaagtaaa gagatagaat ctgatttggt
     1021 caattgttgg agtaaaattg tttatccgga tgatgttcaa atatggaaag atgatataca
     1081 agaattacta catggaaaaa aaggtgagca caatttagaa tataggttga ttaataaata
     1141 taaagaaata gtatggattt cttgtagagg taaagtttat gtgtcggatg acccaaaaac
     1201 tatatttcta gtcgggagaa taaagaatat tggtgaaaaa aataaatttg attctatcac
     1261 aggaacgtgg aatagagaac aatttgaaca tagaatgaat tatcttataa aagagaaaat
     1321 ttataaaaat ggtgctatgt ttattatgga tattgataat tttaaaaata taaatgaaaa
     1381 atatggacat tcttatggtg acaaagtatt gcgtgcaatt gctactgaag tattagaata
     1441 tcttccaaaa gatgtaagat tgtataggtt agatggagat gaatttgcat ttttttaccc
     1501 tatgtgtact aaagaaacta tagagaaaat atatgaaaag atacagatgt atacaaatac
     1561 tcagcatgaa attgaatcaa ataagtacta ttgcacagtg actgcaggcg ttgctatgta
     1621 tccagaagat ggagataatt atttagattt atttaaacat gctgatattg cattggatat
     1681 agcaaaaatt agtggtaaaa atagaattaa gtttttttca caagagctct atgaaaataa
     1741 actaaaggta atttcaatgc aacaaaaact aagagagtgc gttgaaaata attttaatga
     1801 ctttgagctg ttttttcaac cccaggtaaa tgctgttaca aaagaggtaa taggggcaga
     1861 ggtactttta agatggcatt cgagtactta tggagaagta tctcctgttg aatttatacc
     1921 aatactagaa cagagtaatt taattatacc agttgggaag tggattataa aagaagctgt
     1981 aaaacagtgt aaagaatggc ataaaataaa tccagacttt aaaatatctg taaatgtatc
     2041 gtatattcag ttaaaggaag atttttttag agattttata gtagaatgtt tagtagagta
     2101 tcaattaaga cctgaatttt taattttgga attaacagag aattgttgga taccagatat
     2161 aaatttacta aatgataaat ttattagttt aaagggtata ggagtatata ttgcaataga
     2221 tgactttggt acaggatatt catctttaaa ttaccttaaa gaactgtctg ttaatataat
     2281 aaaaattgaa agaagttttg ttaagaatat tacatataat agttatgaat atacttttct
     2341 tgaatatatt attaaattag ctcatattat aaatttaaaa gtttgtgttg agggaataga
     2401 gtcttatgaa gagtatgata tagtaaaaag cttaggggta gatattattc agggtttttt
     2461 atttggaaga cctgtaagtg cctctgaatt ttataaattt caactatcaa agtgatgtat
     2521 ataaaatgag atatatagta tataaaaata gggcaaagtg gaagttttga agtttattaa
     2581 aaatttacac tttaccctat tttgttatgt cttctataaa ggattaatat actacactaa
     2641 ctattatata ctttcactcc aaatttagag attatttcac tagctttttg gacatcttcc
     2701 ttagtggcat caggaacatc ttttagttca taatcgatac ctaaactttc ccatttgtgt
     2761 attcccatag aatggtatgg tagcaattca aatctttcta catttttcaa tgtagctaca
     2821 aattgaccta gtttttctaa attatctata tcatcagtaa tgccaggaac taaaacatgt
     2881 cttatccata caggaatatt tcttgattct aagtgtctag caagttttaa tgccttatcc
     2941 ataccaacac cagtcaaatc aatagatttt tcctcaacca tatgttttaa atcaagtaaa
     3001 accaaatcag tattatctaa aactgggtct atagtttcta tatctacaaa tccagatgta
     3061 tccaagcaag tgtgtatatc attttctttt gcttttttaa ataattcact taaaaattct
     3121 ggttgaagag tggattcacc accagaggca gttatacctc caccagaaaa cttcataaaa
     3181 gaagtatact taagagcatc cgttattatt tcatcaactg tgtattcttt tcctgattta
     3241 atatcccatg tatccctgtt atgacagtat ttgcatctaa gaggacaccc ctgaaaaaat
     3301 aatatatatc ttattcctgg tccatctaca gtaccaaacg tttctataga atgtatcttt
     3361 cccttaatca tagagttcac ctcacaatat attttaataa ccttatcaat agttataata
     3421 tttctctaaa aaaggccatc ttataccaga aataattcaa atataagata gccttttatt
     3481 tttatttttt acacagtagt aatcttagtt aaagtataaa aatttaaaga ctaagccatt
     3541 ttaccgtgga atgttctgtt tataacatct aattgttgct ctttagttaa ttttatgaag
     3601 ttaactgcat atccagatac tcttatagtt aattgtggat attcttctgg atgttccata
     3661 gcatcttcta aagtagctct atcaaataca tttacattta agtgatgagc attttgagcg
     3721 aagtatccat ccatcattgc agaaagattg tttattcttt cagtcatatc ttttcctaaa
     3781 gcagcaggta ctatagagaa agtattagat ataccatctt gagcatgttc atatggtaat
     3841 ttagcaactg aagataatga agctaaagca ccattagtat ctctaccatg cattgggtta
     3901 gcaccaggag caaatggagc accagctctt ctaccatctg gtgtattacc agttttctta
     3961 ccatagacaa catttgaagt tattgtaagt atagattgag taggataaga atttctataa
     4021 gttttattct ttcttatttt attcataaag ctttcaacta actctacagc tatactatca
     4081 actctatcat cattatttcc gtattttgga taatctcctt ctatttcaaa atcaacagct
     4141 attccttgtt catttctaat agttttaacc ttagcatgtt ttatagcaga taatgagtct
     4201 gcacaaactg ataatccagc cataccacaa gccatagttc taaatatatc tctatcatgt
     4261 aatgccattt ctaatgcttc ataagaatat ttatcatgca tataatgtat tacatttaaa
     4321 gtatttacat ataatgttgc taaccaatca gtgaatggtt caaatttact cataacttca
     4381 tcataatcta agtactcaga agttataggt tcaaatcttg gtccaacttg aacaccagat
     4441 ttctcatcta caccaccatt tatagcgtat aataaagttt tagctaagtt aactctagct
     4501 ccaaagaact gcatttgttt accaattctc attgcagata cacaacaagc tataccatag
     4561 tcatctcccc agtatgctct cattaaatca tcattttcat actgtactga acttgtatct
     4621 atagatactt tagaacagaa atctttgaat ccttgaggta atttagttga ccatagaact
     4681 gttaagtttg gttctggaga aggccctaat gtatatagag tatttaacat tctaaatgag
     4741 tttttagtaa ctaatgttct accatctatt cccatacctc ctatacactc agttacccaa
     4801 gttgggtctc cagagaataa gttattgtaa tcaggagttc ttaggaactt aaccattctt
     4861 aatttcataa caaaatggtc catatactct tgtaattctt cttctgttac gattccagct
     4921 tttaaatctc tttcaaagta tatatctaag aaagtagatg ttctacctaa agacattgca
     4981 gcaccatttt ggtctttaac agcacctaaa taaccaaagt ataaccattg tacagcttct
     5041 tttgagttag ttgctggttt tgatatatca aatccataag attcagccat ttttttaagt
     5101 tcatttaaag ctgatatttg ctcagttatt tcttctctta atctgataac ttcctcatcc
     5161 atgcaagaaa cttctaatga tttcttttgc tcatttttat cttctattaa agcatcaaca
     5221 ccatatagag caactcttct gtagtcacca attattctac ctctaccata agcatctgga
     5281 agacctgtta ttataccaga ttttctagca gctctcattt ctggagtata aacatcaaaa
     5341 actccttggt tgtgtgtttt tctgtattta gtaaatatat cttttatttc tgggtctaat
     5401 tcatatccaa aagcttcgca tgaattttca accatcttta taccaccata tggcatgaca
     5461 gctcttttta aaggggcatc cgtttgtaac ccaactattg tttctaattc tttatctaaa
     5521 tatcctggag catatgcagc tattccagaa acagtttttg tatcaacatc taaagtacca
     5581 ccattttctc tttctttttt aaataggacc attgcttcgt cccataattt tttagtattt
     5641 tcagtggcac cagctaagaa agagtcattt ccctcatatg gagaatagtt taattgtata
     5701 aactctctaa catttatttc tttagtccat cttcctgttt taaatccttg ccatgcattc
     5761 attaagtatt tcctccttag atttaaatga taaataatac tattaaaatt aatttttata
     5821 tacttaattt attttatata tttttttaaa aatatatttt ctaatataat aatagcatat
     5881 tattcgtatc ctgtatacat aaaaaataaa aaattgtcgc tttaaagtat aaaacagatt
     5941 atatgttaat aatgtggtga aattataccc atatataaat aaaataaaac aaataaatag
     6001 ctaattaagg agaaaatatt ttttattttt tgtttaggat aaataaattt tattatggaa
     6061 aaaagaaaaa gcatacatct tcacaaactg aatatttatt taataggggg aggtgataga
     6121 ttgtttatca cagtggtatt atttttagta ggtttcctat taattactaa aggcgcagat
     6181 atctttataa attgtactgt agagataggt aaaaaaacga atatatcaga aattatactt
     6241 ggagctacta tagttagttt tgcaacaaca ttacctgaat ttacagtgtc tctacttgct
     6301 tctattgatg gtcatactac tatgagttta ggaaatgcag ttggttctat aatatgtaat
     6361 acagggttag cattagggtt ggttgttttt ataagtccat ttaatgtaga taaaaaaatg
     6421 tttttttcta agtctttact attaatagta tccgttatag ttttaatttt attgagttta
     6481 gatggagtta taacaagagg tgattcatta ttacttataa taatattaat cttttatatg
     6541 gttaataatt atagaagtgt cgttggaaaa tctgatacta aaaatagaaa tattaaaaat
     6601 aacactatta aagacatatc tactaaaaaa gggaaaaatt atagaggttt ttccgtatta
     6661 gaaattgtaa aaatactatt actttttgct acaggattga taatgatgat aataggttca
     6721 caaatcctta tagagagtgg agtaataata gctagttttt taaatatacc tcaaggtata
     6781 gtaagtttaa ctataatagc acttggaact tctctgccag agatagtttc gtcgattact
     6841 gctataagaa aaaatcatca tgaaatatca gtaggaaata ttttgggtgc aaacatattg
     6901 aatatagtat cagtaatagc tgtatcagca ataccaaata acataccaat actatctcaa
     6961 aatagacaat tggatatacc attcatgata ttattattat taatagtaat aataccaaca
     7021 cttaaatcta ataaacttag tagaatacaa ggtatattga tgttattcac atattttctg
     7081 tacatatcaa ttttgtattt catgtatatt atttaactat actgtttaaa atattaattg
     7141 cagaatatcc taaaaaagta tataatggat aggttaagat taattgataa cggagaggaa
     7201 taatatatga atataacaaa gtttgaagat ttaccaataa gtgagggaat aaaaaaagct
     7261 atagctgaaa tggggtttga agaaccatct cctatacaag cacagtctat acctgcgatt
     7321 ttgtcaggta aagacgttat aggacaagct caaactggta cgggaaaaac agctgctttt
     7381 agtatcccta tactagaaac aatagaccca aataatagaa gtttacaagc tgtagtgctt
     7441 tgtccaacaa gagaactggc aatacaagta tcaacagaaa taagaaagtt agctaagtat
     7501 tcgcacggaa taaagacatt acctatatat ggtggtcagc caatagatag acaaataaaa
     7561 tctctaaaga gtggtgtgca agttgtaata ggtacaccag gacgtacaat agaccatatc
     7621 aatcgtaaaa cattaaagat ggataatgta aaaatgatta tattagatga agcagatgaa
     7681 atgctagata tgggatttag agaagatata gaaatgattt taagtaagat tccagaagaa
     7741 agacaaacaa ctttcttttc agctactatg ccaagaggaa ttttggaatt aactaagaga
     7801 tatcaaaaag acccagagca tataaaagtt gttagaaaag aacttacagt ttcaaataca
     7861 aagcaatact atatagaaac taggtcatca aataaattag aagtattatg tagattagta
     7921 gatgtatatg accctaaact atctgttgtt ttctgtaata ctaagagaaa agcagacgaa
     7981 ttggtaggag atttacaagc aagaggatat tttgcagatg cattacatgg tgacttaaaa
     8041 cagactcaaa gagatatagt aatggataag tttagaaatg gtacaataga tatacttgtt
     8101 gctactgatg ttgcagctag aggtatagat gttgatgatg ttgaatgtgt attcaactat
     8161 gacttaccac aagatgaaga gtattacgtt catagaattg gtagaactgg tcgtgctggt
     8221 agagaaggta tgtcatttac ttttgtattt ggaaaagaaa tgagaaagat gaaagatata
     8281 gaaagatata ctaaatctaa actaataaag cataatatac caacaataac tgatgttgaa
     8341 gagaaaaaag taggtacttt ctttgcacaa gttaaacaaa ctatagaaga aggtcactta
     8401 actaaacaat tacaatggtt agaaggtttc tgtaatgatg aagattatgc aatggttgat
     8461 atagctgctg cacttgtaaa actatctcta ggtgaagaaa tgaaagaaga aataatagaa
     8521 gaaaaaccta gaagagagcg tggagataga aaaggtggta ctggagctaa agatggtatg
     8581 attagattat ttatcaatat tggtagaaat caaagagtac aagcaaaaga tatagttggt
     8641 gccatagctg gagaagttgg aataccaggt aaagtagtag gtactataga tatatatgat
     8701 aagtatactt ttgttgaaat acctaaaaaa gatgcaaaaa cagtaattga aaagatgaaa
     8761 gatattaaga taaaaggtaa taagattaat atagaaaaag caaataagaa gaaaaaataa
     8821 cgtatagtat acaaaactat aattagaaaa tatataaaat aatatattgg atatttaaaa
     8881 agcctgatgt gttttcaaaa cagatagtag ataatctgta agagttaaca gcataaggct
     8941 tttcttgttt tatatgatgt tataattttc cagattgttg tgaaaaatgt atattagttc
     9001 ctttttttca aatctgattt gaaaaagaga atattaatta tctatatagt ttagattata
     9061 ataaaaaatg taagataaca aaggggagaa aaagatgtca atgacttata tggaccctag
     9121 ggtttttttg attttagaaa tggtgttaga agaagacaca aatactctag aacaattttc
     9181 aaatgttttg ggtgttagta ctaggactat cagaaactat ataaaccaga ttaatcgaga
     9241 attaaaaggt ggtattgcta aaatagttaa aaatgaaaaa ggtacatata gtataagaat
     9301 tgaggatgaa agtaaattaa ttgagattgt aaattttaat agaggaaagc tatcaaattt
     9361 tataaattta aattcacctg atgaaagaat aaattatgtt cttgatattt taactatgac
     9421 caacaatcca attaccatag atgatttggc tgaagagata tgtataggaa gaacaacatt
     9481 aataaaggat ttaaaaaaag cagacagaat tttagctgaa tatgatttag aattaaaaag
     9541 gaagccaaat ataggtatga ttttagttgg tgaagaaatg gatataagat tattaatcct
     9601 tgatagattg tatgaaaatt atattgatgt cttggaaaac gttaatcaga taaatttagt
     9661 taaagattat gatattgaat gtcttagaga tgaattaaaa aagttattta aaaaagaaga
     9721 actctacata acagaacagg tcttgagaga tgttgaaaga tatataatca tgtctgtttt
     9781 aagaaatcta aatgggtaca aatttgaaaa gatagataag agatttgaag tgataagatg
     9841 ttcagatgaa tatactttag gattaaagct caaagcttta ttggaaaaga tatttaatat
     9901 agttttaaat gaaaaagaaa ccatattttt gacaatgcca ttaataggta gaaaagctcc
     9961 tagtacaaaa ttagcactta gcagtataaa gataaatgat agcgtaaagg aagttgtaga
    10021 tgaagtaact agttttttat tagagacctc agggattgat tttaaagaag ataaaaagct
    10081 tatagaaaat ttggaatatc acttgtattt tgcacttaat agaatgagat tcaacataag
    10141 ggtaaaaaat cctcttttac aagaaataaa ggaaagatat acatttccat atagcgttgc
    10201 aaagatagct gcaatgataa ttgaggaaaa gtttgacttg aaaatatgtg accacgaaat
    10261 aggatatata gcattacatt ttggaagtta ttttgaaaaa aattcaagaa aagttctaaa
    10321 tgtaaatagg gtagctgttg tttgtggaac aggtcttggg actgcacaac ttattagaat
    10381 aaagatagga aaaatacttg gagaaagtgt agaagtaaat actttttctg atatagaagc
    10441 taaagctaat ttagatttat taaagtatta tgatttagta tttacaacag tagatttcaa
    10501 aacagactta gatgttccaa tttttagagt aaatgcgtta tttaatgaag aaagtataaa
    10561 gaaagagata gaaaatgcaa tacttttgaa aaatagtata aatcttaagt ctataaaaaa
    10621 gattgaaaaa aatatccctt ttataggtaa attaattgaa gaggataagt tctttatatt
    10681 gaataagagt acgtttatgg aaaatttaga agatatgtta gaaaaattag ttcataaagg
    10741 aattattgat atagagttca aaaaaaaggt attaaaaaga gaaaagaaat cttcaacagc
    10801 attagataat tatatagcat tgcctcactc agttaatact aatggggaaa atctttatct
    10861 ggcatttgga atattagaaa aaccagtgat ttgggataca aaggaaatta gaataataat
    10921 attgatgata attccagata agaatgtaga tagtacagac ctgataataa aaagttatga
    10981 agaagtactt gaagtaggga gagataaaaa gatggtagaa gaacttgcta aggtaaaatc
    11041 atttgatgaa ttttataaaa taattaccaa gaggaggtaa taatatggac ccagtaattt
    11101 ttattatagc atcacttatt acagtgtatt tattaaatat ttttcttgga tacttacagc
    11161 ttaaagattt taataaaaat tatattgaac taaaaagaaa aggaagagtg gcaattggca
    11221 gaaaaaaagg aagaatttca tcgggtacaa ttgtgttgat acttataaat gatgatggtg
    11281 tgattgtcga gactagaaaa atgcaaggtg ttacagtatt ggcaagagta aagtcatttg
    11341 aaggtttggt aggaaagagc ttagagtata tagaaaaatc agatttaact gtttacaata
    11401 aactacttaa aaaagcaata ctagatgcag tcaaacagta cataacattt gagaaaaata
    11461 aatgtgaaga tacaaataat ctgagtactg atgaagagtg taggatggaa gtagtttaaa
    11521 aaaatatatt tataaggagg agttaatatg acgcaatttt ttcaagtatt agcaagtggt
    11581 gcagatagtt ttatgaattt atttagggca ggtgggcaac aatttgtagg ttttgtaaca
    11641 gatatagtac cacttttagt agcattatta gttacaatga atgcaattat caactttatt
    11701 ggtacagata gagtcgagag acttgcaaaa aaatgttctg caaatatatt tactagatat
    11761 ttgatattac cagtccttgg tacatttgta tttgcaaacc caatgacact atcattagga
    11821 agattcttgc cagaaaagtt taaacctagt tactttgcag cagcaagctt ttcatgccat
    11881 acaatgaatg gattattccc acatatcaat ccaggtgaac tatttatata tctaggaatt
    11941 gcaaatggta taacaacttt gggattctca acagcagatt tagcagttag atatttgtta
    12001 gtgggtatag ttgcaaactt tattaaaggt gtagttactg actatacaac aaaatttgta
    12061 gagaaacaac aaggaatagc attaaattca gatataaaga ttggataatt actttaaggt
    12121 ataaataaat ttttcaaata aaaagatagt gtatagagga ggataaatta tatggcattt
    12181 aacaaagtta aaatagtaaa aggttctgga ggatggggtg gaccattgat aatagaacca
    12241 acagaaaaga agaataaggt agtatatgtg actgggggag caaagccaga aactgcagta
    12301 aaaatagctg aacttacagg atgtgagtta atagatggat tttcacaggg tgttaaagat
    12361 gatgaaatcg catgtgtaat aataaattgt ggtggaacat tgagatgtgg tatatatcct
    12421 caaaagaaaa taccgactat aaatataatg aaaacaggaa aaagtggacc attagcaatg
    12481 tttataaaag aagatatata tgtttcaggg gtaaaaccaa caaatgtaga gcagttataa
    12541 ttgaggtagt aggagggaag aaatatggct tatgatacta aaaagaagat aagtgagcag
    12601 agtcaaggaa ttgttgcaaa aataggtata gcactaggaa atgtgacaag tactcttttt
    12661 caagctggta gggatactat agatacatta atacatacta tactgccttt tatggctttc
    12721 gttgcagtcc taataggtat aataaatcaa tcgggtatag gaaattgggt agccaattta
    12781 cttactccat taatcggaaa tgttggaggt ttagttgtct tatcaataat atgttcattt
    12841 ccgttgttgt ctccgtttct tggaccagga gctgttatag ctcagatagt gggagtattg
    12901 gttggtacag aaataggaaa aggaaatatt ccaccaagtt tagcattacc agcattgttt
    12961 gcaataaact cacaagcagc ttgtgacttt ataccagtag gtcttggtct tgcagaagct
    13021 gaacctgata cagttcaagt aggagttccg tcagttttat attctagatt tttaacaggt
    13081 gcaccaactg ttctattagc atggttagca agctttgggt tatataaata gaagaatact
    13141 ttataaataa ttagagagag gttcagttga tatggaatta atatacagta ctcaaataaa
    13201 taaaatagga gataatgcaa atgaattttt acaacataat atgtttgtaa ctttcaaaga
    13261 taatgctcct caagagttag aaaattactg ttatatacat tctgaaaata atttagtaaa
    13321 agaaatactt acggatgatg tgctatcaat aaataatgtt gattacaaaa ttacttctgt
    13381 tggtgagtta gtaaaccaaa atctttcaga attaggtcat ataacattta agtttacagg
    13441 tgaaaaagat ggagcaattg gaggaacctt atatcttgaa gaaaaagaaa tagcacctat
    13501 tggcgtaggt actatactaa aaataattag aaaataaaat ttaaaacgaa tctaatcata
    13561 ttataagtaa attatagata aaagtcaatt taactaatca agttaacttt taatgtgata
    13621 aaaaagggga aatgaaaatg agaaaagtgg ctttagtcgt tggaggagga agaagtttag
    13681 gtgaatattt atctaaacat ttagctaaag taggttatga tgttgctatt gcagatttaa
    13741 atgaagacaa cgcaaaaaaa gtagctgaag aaataaaaac tgaatttggt tgtaaatctg
    13801 taggatatag ttgtaatgcc atagatgaaa gacaggttat aagtactgtc aaagctattg
    13861 aaaatgattt tgatagaata gatttattag tgtacaatgc aggagtggct gtaagtaaaa
    13921 aaataactga ttttggatac aaagatttta aatttattgt agacgtaaat ttaaatgggt
    13981 actttctatt tgcaagagaa gtatctaaag tcatgatagc aaaaggtatt gagggtagaa
    14041 taatacagat aaattcaaaa tcaggtagag tgggaagtaa gcataattca ggatattcag
    14101 caggtaaatt tgctggagta ggacttactc aaagtttagc gctagatttg gcagaacata
    14161 agataactgt aaatgcactg atgctcggta atttacttga ttctgatatg tttgaaagtt
    14221 taattcctca atatgcagta aaattgggaa tacctgaatc agaagtcaag caagtttata
    14281 tagataaagt acctttaaaa agagggtgta gatttataga tgttgcaaat atgcttacat
    14341 tttatgcttc aaaggaagct gaatactgca ctggtcaatc tataaatatt actggtggac
    14401 aagttatgta aggttttatg gagtgtctca agatgaactc tttagttcat gaggcacttt
    14461 tttgtataaa attaaatata ttttcagcat ttaaacaatg aaaaagaggt ttatctttat
    14521 tttgagatag cctcattttt gtaattaaaa aacatagtgt ttaagtaaac atataagatt
    14581 gttagttttt taaaagagaa ttttttaata atattatatt tatgaagtat ttttaaactt
    14641 aatttgataa aatatagcta tgttttatat actgtagttt tgagcataga aagtttaata
    14701 aattatagta tatatgttaa tttttaataa ggtaagaaag tagaaagaag gatattttat
    14761 ggatataata aaaaaattaa gtcatgggtg tacattagat tgtcatgact gttgtaaatt
    14821 caatgtttat actaaaggaa ataatgtagt aaaaattgaa ggagataaaa atcatcctta
    14881 tacaaaaggt tttatatgca aaaaagggat ggcccattta gatagattaa atcataaaga
    14941 tagaataaag actcctatgc ttaaagttga tggagtatgg aaagagattt cttttgataa
    15001 agctatagaa ataatggcag aaaagcttac atactataaa gaaaagtata catcaaagtc
    15061 tgtcatgcat tatgaccaat atggaagtgg gtctgtgcta aaatacatag gagatatatt
    15121 ttttaatttt tatggaggtg ttagtagaca taaggggggt ccctgttgga gtgcagggat
    15181 gcatgctcaa aaatatgatt ttggagtagc taagagtcat gctatagaag atatgttaaa
    15241 tagtaaaagt atatttgtgt ggggaaaaaa tccagcatat actacaattc atactatgca
    15301 aataattaaa aaagctaaag aaaaagggat aaagatagta gtgattgacc ccatatatac
    15361 aaaaacagct caaatagcag ataagtatgt acaagtaaat cctggaacag atggagcttt
    15421 agctatagct atggcaaaaa ttatagtaga agataaatta tatgatgaag aatatataaa
    15481 ctcgtatgtt attggttttg aagaatataa aaaatattta tcttcattgg aattaagttt
    15541 tttaattgat gaatgtggtg ttaaagagaa tgatataaga gagttagtgg atttatatac
    15601 taacaaatat tcaagtataa atgttggata tgggcttcaa aaatataaaa atggtggaaa
    15661 cacaataaga gcaatagatg ctttaggtgc tataactggt caaataggat ttagtggtgg
    15721 aggggtaaac tatgctaata aagtttatcc gagtgttata aattctgacc cttacaatag
    15781 ccaatcatat ggtgaagata gggagtttta tgtaagtaat atcagtaaat ttatagaaga
    15841 atctttaaaa aatacatcaa ataaagtaaa ttatgcatca gatgaacttg atatggcatt
    15901 acataaagta aattacatat cagatgaact tgatacaaca tcaaataaag taaattatgt
    15961 atcagatgaa cttgatataa catcaaataa agtaaattat gtatcagatg aacttgatat
    16021 gacatcaaat aaagtaaatt atgtattaga tgaacttgat ataacatcaa ataaaataga
    16081 ttatatatca aatgaattgt ataatttatc taataagtca atcaaagata atattcctat
    16141 aaagatggct gtgataacta aaagtaatat gctgaatcaa ctgccagatt tagtagaatt
    16201 ggagagggtg ttttcaaaaa ttgaatttaa agtatgtttt gatatgttta taactgatac
    16261 agctacttta tgtgacatgt ttataccatg tacaaataca ctagagagtg aagatataat
    16321 ttatagttca atgaccaatc catatataac ctataatgaa agagctgtaa agccagcaca
    16381 taaattgatg gatgaatatt acttctttat ggagctagct aaaaagatgg gattaaatga
    16441 ttatcctttt gtagaaaaga gaacttattt agaaaaagtg attgaaccac ttaagcgttt
    16501 tgacaaaaat ctggatatag aaaaacttaa aaacaattac tttactatac ataaccctgt
    16561 tgcttgggaa gataagaagt ttgagactcc atctggaaaa tacgagcttt attcagaaag
    16621 tataaaaaac ttgggaataa gtccaacacc tgtatatata agcaataaat ataaagaaat
    16681 agaagataaa aatatttctt ttagattatt aactaatcat catgcagata ctttatttag
    16741 tcagcatttt atggacaaaa aatctatagc tcaagcatat ataaatcgga gaatggctaa
    16801 aaaagtaggt attgaggaca aagatattgt gatattgagg tcaaaaaaag caaaaataaa
    16861 tgtacaaata aatatagatg atggagtagg taattatata gtaaaaatgt atgttggttg
    16921 gtggaagaaa catggaaatc ctaatagttt aacagacact ggtatatcag attttggggg
    16981 tcaggtaaca tataatgaaa gtatggtaga aataatacga caaaactagt taaatttcat
    17041 tgaaggaata aaaatataat tatagaattg attaaaagtt actattttta caaaactatt
    17101 gaaggaggga tttttgatgg taaattattc cttagaacat aagaatctat acatagaatt
    17161 tatgtgctca gaactagacc accatgtagc caatgaaata agggaagaaa tagataactt
    17221 attaagtgta aatcaagtaa aaaatgttgt atttaatttt gaaaatatta attttatgga
    17281 ttcttcaggt ataggcgtca tcataggtag atataaaaag atttctaatg aagggggacg
    17341 agtttcagta attaatataa gttcacgagt taagaagatt tttgatttat ctgggttaaa
    17401 taaaattatt ggcatttatg atacgtatga agaagctcta agttctttgt agggaggagt
    17461 atgtgatgaa taatattatg gaagttaaat tttcggcaat atctgaaaat gaaagtttag
    17521 caagagttat agtagcatcc tttgcagcta agttagaccc aacagtagat gagttagtag
    17581 atataaaaac tgctgtctct gaggctgtta cgaatgctat aatacatgga tatgaagaag
    17641 acagttctaa gtttgttttc ttaagatgtg agatagaagg aaatactata aagattatag
    17701 ttgaagatga agggtatgga atagaaaatg tggagaaggc aatggaacca ctttatacat
    17761 caaaaccaga acttgataga tcaggaatgg gattcacagt aatgaaaagc tttatggacg
    17821 atgtagaggt aagttctgta aaagataatg ggactagaat tgaaatgact aaaaaaataa
    17881 atgtgcctaa ataaagtcca aaagtgaggt tttattatgg aagtaactgt tgccagagaa
    17941 gaaaaaaaac ctcttcttag tcatgaagag actctagaac ttattgaaaa agttcaaaat
    18001 ggagatgaag aggcaaaaga aatattaata tcaagcaatt taggtctagt taggagcgtt
    18061 gtatctagat ttttaaatat aggatatgat agagaagatt tatttcagtt aggttctata
    18121 ggcttaataa aatcaatata taaatttgac ccaaaattta atgtaaaatt ctctacttat
    18181 gcagtaccaa tgattttagg tgaaataaag agatacttaa gagatgatgg tatgataaaa
    18241 gtatcaaggt cattaaagca aatagctgta aaggcaaaga tggaaagtga agctttaact
    18301 aaaaaattag gtagagagcc gagtatagaa gaattagcta aagcaataga tgtagaaaaa
    18361 gaagatttag taatggctat ggaagctaat ttcaatgttg agtatttgca aggagttatt
    18421 catgaagagg aaggttctcc aatatgcctt attgataaaa taagcatgaa aggagaaagt
    18481 gaagaagaaa aagtagtgga taatatattg ttaaaagaca tacttggaag actggataag
    18541 agagagcgtc aaataatagt tctcagatac tttgaagaca tgactcaaag tgaaatagga
    18601 gagatgctca atatatcaca agttcaagta tctaggatag agaagaaagt attgtctaag
    18661 ttaaaagaat atatatcgtg ataatactta tgatatgtag aataacaaaa tataataaat
    18721 atat
//
LOCUS       DAMKNB010000071        18678 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.073, whole genome shotgun sequence.
ACCESSION   DAMKNB010000071 DAMKNB010000000
VERSION     DAMKNB010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 18678)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18678)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18678
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.073"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            complement(<1..666)
                     /gene="yqeC"
                     /locus_tag="PC494_002739"
     CDS             complement(<1..666)
                     /gene="yqeC"
                     /locus_tag="PC494_002739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative selenium-dependent hydroxylase
                     accessory protein YqeC"
                     /protein_id="HDF3913230.1"
                     /translation="MELSNIIEKNEIITVVGAGGKTSLINYFANFYRDKLKVLLTTTT
                     KIYVPNDYDNIIITIDGTVIPSICHGITVCGSYINNENKLVSIDSSILDEIVDQFDLV
                     LIEGDGSKRKKLKGWNAKEPVVYHKTTKTIGILDITSFGMNINEENIHRVEIFKKIAN
                     LDTSSINSSSTVSIENLKNIVLNPNGLFKNYSGKRVLFINKVENEKYKNLAIKLIENI
                     KEYE"
     gene            complement(849..2126)
                     /locus_tag="PC494_002740"
     CDS             complement(849..2126)
                     /locus_tag="PC494_002740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDF3913231.1"
                     /translation="MSNRIKNIHYGTQRQQLKNLTKKEYQALREMCFLAKNLYNVGTY
                     NVRQHYFNQGEHLNYEANYHVCKENENYKLLNSNIAQQILKEVDSSFRSFFGLIKLAK
                     EGKYDFRGIKSPKYLDKEGFFSIIIGQIRIKEDGILNVPMSPAFKKLYGKVSIKVPQN
                     ILEKKIKEIRIIPKHKARFFEIQYCYEIPKSEEVSNQKNALAIDLGLENLCTCVTNLG
                     DSFIIDGKRLKSVNQWANKQNDKIEALKLKKNITAITRKQFKVWNKRNNQVKDYVNKT
                     CFYIIDYCVKNNIGNLIVGYNAKLEKSDNMERKIYRNFIRIPFGEIKGKLEYLCKIKN
                     INFIRQEESYTSKSDFFADDFLPDINVDNVKKYDFKGERITRGQYKSSVGIIINADVN
                     ASLNILKKSQVVNLSNLQNNPQILKQPQRVRIS"
     gene            complement(2265..4571)
                     /locus_tag="PC494_002741"
     CDS             complement(2265..4571)
                     /locus_tag="PC494_002741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-dependent oxidoreductase"
                     /protein_id="HDF3913232.1"
                     /translation="MINKGIRKIDSTAIVTGKPLYTEDLIMHKDVLTLKLLRSPHAHA
                     KIKNIDTSKAEKIPGVVGIYTYKDVPQVRYCVPGQTEPEASPYDRVLLEDTVRFIGDE
                     VALVAAEDEKTALKALKMIKVDYEVLKPVFDAREAEGNEVVIHPEKDIVEPYPFGLDA
                     KNNIVSKEFFEFGDVEAKLKESDFVVESSYKTQSQSHCMMETHRSYSYKDINDRIVVV
                     SSLQSPHNVKRILRKVLGIPSSKIRVIKPRIGGGFGGKNIAATDIFTAFVTMKTGRPA
                     KFVFTRSETFVGSNSRHEMFFDVKVGADKEGNLKAIELKSLNNTGAYGGNGVSVSSES
                     GHNTLPIYNDIDAVRFNARTVYTNRLPAGALRGYGATQGIFAIDSAIDELAHKIGMDP
                     LEFRIKNIIDRYTNGKAAEDEILSCELRQCIEKGKKLINWDDKYPCKDIGNNKVRAVG
                     MAVANHGSGIPRVDMATVTIRMDEDGTYKLLSGLADLGQGADTIQAQIAAEALNTTVD
                     RISIYTGDSDLCPYDTGAFASCTTTVTGNATIKTANKLKDILLSVAESKLGFKKEDLE
                     LGKDRVFVKNDNSKFVLLEELGRESVGGIGFASDDVPVVLEATESFGMLKKIKPFIAG
                     FAEIELDKNTGEYKVINFACVPDCGTVINPTLARIQVEGGVMMGIGFAMYEDPIFDKD
                     GRLLTDSFLQYKVPTKKEVGNILVDFAENFDPGGPYGAKSLGEIVIHTPAPAIANAIF
                     NATGVRLRELPMTFEKVYMGMKNNNKQL"
     gene            complement(4564..5358)
                     /locus_tag="PC494_002742"
     CDS             complement(4564..5358)
                     /locus_tag="PC494_002742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD binding domain-containing protein"
                     /protein_id="HDF3913233.1"
                     /translation="MVTIKEYSVPQSLEEAYKILISKKNNVILGGCGFIKLSNKNIGT
                     AIDLKDINLNYIKEDKKNILIGADTSLRSLEIDKTIKNYCSGILSSAVSNIVGVQFRQ
                     GARIGASVFSKYGFSDLIPALLVVGAKVRLYNKGILELSEFLDSELSRDILVEVILPK
                     KDAIAVFDSIRKCTGDFSVLNSAMLKENDTYKIAIGARPQKARLALEASNILNKEKDI
                     DKASIVASKELTYGSNMRASKEYRKDMASALVKRMYNAIEEGMYND"
     gene            complement(5465..6823)
                     /locus_tag="PC494_002743"
     CDS             complement(5465..6823)
                     /locus_tag="PC494_002743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine/pyrimidine permease"
                     /protein_id="HDF3913234.1"
                     /translation="MKAKSTSKFELDGIPPLKEAIPLGLQHLMAMVIGSCLPAILIAN
                     AAGLNHKMSTLLIQAALVFAGLSTLLQLYPIPLFKGFKLGGGIPVIMGATAMFIGAGV
                     SVASKYGLPVLFGSQIIAGIVIIIIGFGLKKIRFIFTPAVSGTIVACMGLGLFPIAIK
                     NLAGGMGNETFGNPINFIVGISVSLMILGLNKYGKGLFKDASILVSIIFGYILSLILG
                     IVNFSSIQEFTLVALPKPLAFGLDIRLEVVVMFSIIYLVEIADIMGACTLSAVGGLNR
                     QVTDEELSSAVLGNGVLSTIGALFSATPMGMFGQNSAIVSNTKVVSKFVLAIGGIGLF
                     LAGISPLLANLIRTIPPCVVGGATLVIFSTLTTSGLRLVSMDGFNQENSMILGLSMAS
                     GIGFMVAPQVLEKFPKFIETLLADSSVVSGAMVAIIIQALYMVKFPGNKSDKVEDKNK
                     SL"
     gene            complement(8169..9134)
                     /locus_tag="PC494_002744"
     CDS             complement(8169..9134)
                     /locus_tag="PC494_002744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3913235.1"
                     /translation="MVMQVQEKILELLYTINEDVVSIKNDMSEVKQEINVLKEDMSEV
                     KQEITVMKEDMSEVKQEINVLKGNMSEVKQEMIVMKEDMSEVRQEINIMKEDMSEVRQ
                     EINTMKEDMSEVRQEMTVMKEDMSEVKQEINVLKEDMSEVRQEINIMKEDMSEVRQEM
                     TVMKEDTSEVKQEINVMKKDMSEVRQEITVMKEDVSEVKSEVNFMQNKINNINEDMNG
                     IKDEVSIANEKLYGIEIKIDSLECEDKSMKEIQIEQNNILGSLLHNSEINKATHDNIE
                     HNIAYIKGDTNSIKEDIAEIRRDLNLVELATSKNWSDIVKLKSVK"
     gene            complement(9364..10449)
                     /locus_tag="PC494_002745"
     CDS             complement(9364..10449)
                     /locus_tag="PC494_002745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HDF3913236.1"
                     /translation="MYNFLGKELKSPLIIGSGPLTYSAAGCKILSDAGAGAVVTKTIR
                     KERAINPAPHMVRNTANALLNNEKWTDFEPEQWIDFEIPQMKRDGTVCIASIGHTIEE
                     SSELVEKVANAGADFIELVSYDYRDLIPMLKDAKERVNIPVIVKLPPMIDEIGDFAKK
                     LEEAGADAITACDSVGPAFRIDIETGQPLLGGNGIGYLSGETIKPITLQRIYEIKKQV
                     NIPIIGLGGCVSGDDALEMIMAGADFVGICSVVILKGAQVISKIHDDLKSNLNRLGYN
                     TIENACGIVHNHMGDVNERLSFEFTYDEEKCTKCKMCERVCAYQARKLNDKMELNEEE
                     CRYCGLCISVCKPKALGRKISCSELNV"
     gene            complement(10485..11798)
                     /locus_tag="PC494_002746"
     CDS             complement(10485..11798)
                     /locus_tag="PC494_002746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HDF3913237.1"
                     /translation="MIAIKSKYLISSADEIYANSAVVVENDIIKDILPNEEVEIKYKN
                     IEEIIDKSDAIIMPGFVNGHMHQYGVLSRGIPANVHFTDFEGFLNDYWWPFIENRIGL
                     KEVKATTKASAIELIESGVVAFCDTLEAPNTEEGTLIEQGKILEEIGMKAILSLESCE
                     RISFENGLRCLDENSNLIKWSRENSKLINGIMCTHTSFTCSDRFIKKAKEDAKKLNSP
                     MQFHLCESIYEPNYAEKHFGKKAVDYYNDLDILDETILASQCVKVNDEEIDILKEKGV
                     KVVHMPLSNCEVGGGFSPVPKMIKKGIKVALGTDGYINDFFEVMRGAFLMHKSVEEDA
                     SVMPANLVFRMATEHGAYVLGLQNSGKIAVGNKADIIVMEDEFKTPVTLDNIFDQIVV
                     QGKKEFISNVYIDGRHILKEKQLVDLDKKAIVKEMKEVACEFWKF"
     gene            complement(11799..14090)
                     /locus_tag="PC494_002747"
     CDS             complement(11799..14090)
                     /locus_tag="PC494_002747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-dependent oxidoreductase"
                     /protein_id="HDF3913238.1"
                     /translation="MVNKEVRKIDSEAIVTGKPIYTEDLIFHKDVLTIKLLRSPHAFA
                     KIKNIDIKNALKVKGVVNIFTYKDVPNYRYSMVGESYPEASPHDQLILEDVVRYVGDE
                     VAIIAAEDERAAIKAMKLIKVEYEVMTPILDARESEGNKILIHEEDDLFCPFDFGLDA
                     TKNIVSREKMGKGDVEKEFKESDVIVEHSYMTQSQAHCMMETHRAYTYIDTNGRLVVT
                     SANQSAYHMRRQVSKALGIPLSKVRVIKPRIGGGFGGKNIAVTEIYASFVTWMTKRPA
                     KLIYTREETFAMTNTRHQMFFDIKIGADKEGNIKAIDMKALNNTGAYGDNGPSVCSES
                     GHNVLPTYNNVPAIKFDGRTVYTNLVPGGALRGYGATQGTFALDCAIDELAHKLNMDP
                     TEIKLKNIIKKQTEGGIMNFPIRSCALDECIIRGKKLIGWDEKYPVRDIGNNKVRAVG
                     MSVGTHGSGIANIDMAIVNMRMDEDGTYKLFSGSSDLGTGSDTILAQIAAKALNTSID
                     RISVYTGDTDMCPYDTGAYASCTTYVTGNATIKSAESLKQKILKVAQKKLDLPIDDLI
                     LYEDRVCYSEDVEKFVLLSELGKESVGGGNQEVLYSSESYGIQESAKPFLAGFAEIEL
                     DKTTGEFKVINYACSTDCGTVMNPALARIQVEGGVTQGIGLAMYEDPRHGSDGKLQTS
                     NLLQYKVPTKKDIGNIIVDFVDNYEPTGPYGAKSLGEIVIHTPAPAIANAIYNATGVR
                     IRELPITSEKVYMAMKKLNQGGK"
     gene            complement(14080..14874)
                     /locus_tag="PC494_002748"
     CDS             complement(14080..14874)
                     /locus_tag="PC494_002748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD binding domain-containing protein"
                     /protein_id="HDF3913239.1"
                     /translation="MITIKEYVVPKSLDEAYELLISRKNNIILGGCGFLKLGSKNIGS
                     AIDLKDLALDYINETDDSILIGADTSLRTLELNKVIKNYCNGVISNAVSNIVGVQFRS
                     GARVGASVFAKYGFSDLIPSLLVVDAKVKLYKKGVMNLADFLESELEKDILIEVILPK
                     KDAIGVFDSIRKCTGDFAVLNGAMLKEGSIYKIAIGARPRRAKIAYKASEILSLENDI
                     EKAGEVSSEELSFGSNIRGSKEYRKDMAKALVVRMYNSIGGECDGK"
     gene            complement(14913..15359)
                     /locus_tag="PC494_002749"
     CDS             complement(14913..15359)
                     /locus_tag="PC494_002749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2Fe-2S iron-sulfur cluster binding
                     domain-containing protein"
                     /protein_id="HDF3913240.1"
                     /translation="MIIKCTINNKEKELSIRPDDFLADTLRENGYVSVKKGCDTGSCG
                     LCTVMVNDKAVLSCNYLTARVDGQHITTLEGVLDEAKKFGDFLADEGADQCGFCAPGF
                     IMMVLAMKRELQNPTEEEVIDYVNGNLCRCTGYKGQLRAIHKYLNT"
     gene            complement(15431..16837)
                     /locus_tag="PC494_002750"
     CDS             complement(15431..16837)
                     /locus_tag="PC494_002750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HDF3913241.1"
                     /translation="MMDILIKNAIIVTVNKEREVIFDGALVVKDNKIADIGNSKEIES
                     KYTDVKKIIDAKGKVLFPGFINTHNHLFQTLLKGLGDDMVLKDWLETMTFPAANYLEP
                     KDTYDAAMLGCIEGLRSGITTMVDYMYPHSKPGLCDGIIDAYKELGIRGILGRGCMNT
                     GAQFGVHPGIMQDVETVEKDVRRLFEKHHNTENGRIKIGVAPAAIWSNSQEMLEMLWR
                     VVKEYDDALFTVHISETPFDREAAKELHGQYDIDVLEKLGILGPNVLMVHCVYLTEKD
                     MELTKKYDMKVSHNTASNMYLSSGVAPVPEMLKKGITVSLGVDGAASNNSQDMLELMK
                     LTALQHKVNKCDPLAMSAEKVLELATIDGARAIGMEDEIGSLEIGKKADLLIFNPMLS
                     PKAIPMHNPVSTLVYSSSMKNIESVIVDGNIIMEDSKILTANEEKALKDAQDTAERLC
                     VRGTIKNRMEGHKWNSLY"
     gene            complement(16855..18225)
                     /gene="hydA"
                     /locus_tag="PC494_002751"
     CDS             complement(16855..18225)
                     /gene="hydA"
                     /locus_tag="PC494_002751"
                     /EC_number="3.5.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropyrimidinase"
                     /protein_id="HDF3913242.1"
                     /translation="MGTILRGGTIITSDKTYISDLRIEDEKIVEIGNNLEINGDKVID
                     ATGKIVIPGGIDTHTHFDMNAGSITTADNFETGTRAAIAGGTTTILDFAEANEGEDLL
                     QGVEAYHKKASGNCYCDYGFHMTITCLNKDTFNHMEKLISDGIVSFKMYMAYDGMKVD
                     DGTIYRVLKKARDLGCIVGFHCENGDLLDVLIEENIQNGNLEPKYHPLTRPNIVEKES
                     VSRLADITKLSNSKSYVVHLSCRESLETVKMAREKNIDMIVETCPQYLLLEDNLYNKD
                     KFEGAKYVMSPPLRKKEDINYLWEGLSSGDIQTVGTDHCSFNFKGQKDLGIDDFSKIP
                     NGAPGVEHRLALLYTYGVLENRISVNKFVEVTSTNAAKIFGMYPKKGEIAVGSDADIV
                     ILNINKEETISYKTQKQNVDYTPYEGFKVKCKVEDVFLRGNHVVQSCNVKEHPTGQYI
                     KRKITK"
     gene            complement(18358..>18678)
                     /locus_tag="PC494_002752"
     CDS             complement(18358..>18678)
                     /locus_tag="PC494_002752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HDF3913243.1"
                     /translation="VEKADCYTGNTIESERFFPGWLYDEEDEFVQAAYKGLKEAGIDS
                     EITQYSFCTNGSHYAGEAGIKTIGFGPSKENLAHTIDEYIEQEQLFIGTEGYYGILKS
                     VYGK"
BASE COUNT         5612 a         3629 c         1978 g         7459 t
ORIGIN      
        1 ttcatattct ttaatatttt ctattaattt tatagctaaa tttttatatt tttcattttc
       61 aactttatta ataaataata ctctttttcc agaataattt ttaaataatc catttggatt
      121 taatactata ttttttaagt tttcaatact tactgtagaa ctactattaa tactacttgt
      181 atctaaattt gctatttttt taaatatttc tactctatgt atattctctt cattaatatt
      241 cattccaaat gatgttatat ctaatatccc tatggttttt gtagttttat gatatactac
      301 tggttcttta gcattccaac ctttaagttt ttttctcttt gagccatctc cctctattaa
      361 aactaaatca aattggtcta caatttcatc caaaatagag gaatcaatac ttactaattt
      421 attttcatta tttatataac tgccacagac tgttattcca tgacaaatag atggaataac
      481 agttccatct attgtaataa ttatattgtc ataatcgttt ggtacatata ttttagttgt
      541 tgttgtaagg agaactttca atttatctct ataaaaattt gcaaaatagt ttataagcga
      601 agtttttcct cctgctccaa ctacagttat tatttcattc ttttctatta tatttgatag
      661 ttccacactt tcacctctta taaccagttt tctaatctct taattattat agttagacct
      721 ttttagtaaa agtgattttt gaaattccat aaactcgaaa gtaaatagat tctgttgtaa
      781 acaacaaggc ggatccaatt cgccgctaag ctgtaagctt acgctatcag tttatctttt
      841 aaatataatt aagatattct tactctctgt ggttgcttta atatttgagg attattctgt
      901 aaattagata aattaactac ttgtgatttt tttagtatat taagactcgc atttacatct
      961 gcatttataa tgattccaac actggatttg tactgtccac gcgttattct ttccccttta
     1021 aagtcatatt ttttaacatt gtccacattg atatcaggta gaaaatcatc agcaaaaaaa
     1081 tctgatttac tagtatagct ttcttcttgc ctaataaaat tgatattttt tattttacac
     1141 agatattcta attttccttt tatctctcca aatgggattc ttataaaatt tctatatatt
     1201 tttctctcca tattatcact tttttctaac ttagcattat atcctacaat taaatttcca
     1261 atattatttt ttacacaata atcaattata taaaaacagg ttttatttac atagtcttta
     1321 acttgattat ttctcttatt ccaaacttta aattgttttc ttgttattgc agttatattc
     1381 ttttttaatt ttaaggcttc tattttatca ttctgtttgt ttgcccactg attcacagat
     1441 tttagccttt ttccatctat gataaaacta tcacctaaat tggtaacaca tgtacataaa
     1501 ttttctaaac ccaagtctat agctagtgca tttttttgat ttgaaacttc ctctgatttt
     1561 ggtatttcat aacaatactg aatttcaaag aacctagctt tatgtttagg tattattctt
     1621 atttctttaa tttttttctc tagtatattt tgtggaactt ttatacttac tttcccatat
     1681 agttttttaa atgctggaga cataggtaca tttaaaatcc catcttcttt gattcttatt
     1741 tgacctatta ttatgctaaa aaatccttct ttatctaaat atttaggtga ttttatccct
     1801 ctaaagtcat attttccttc tttggctaat ttaattaatc caaaaaatga cctaaacgaa
     1861 ctgtctactt cttttaatat ttgttgcgct atattactat tgagaagctt atagttctca
     1921 ttttctttgc atacatgata attagcttca tagttaagat gttctccttg attgaaataa
     1981 tgctgtctta cattatatgt accaacatta tataagttct tagctaagaa gcacatttct
     2041 cgtagagctt gatattcttt tttagttaag ttttttaatt gttgtctctg agttccatag
     2101 tgtatatttt ttattctgtt tgacatgaac tcacctcctt tagaatatac tctactagac
     2161 attatatacg gtatttttac aaaacaccat atataatgtc catttaatta ctttatttta
     2221 caaaataatt taaatttact tgcttttata catcttatta tttattataa ttgtttatta
     2281 ttatttttca tacccatata aactttttca aaagtcatag gaagctctct taaacgaact
     2341 cctgtagcat taaatattgc atttgctata gctggtgctg gtgtatgtat aactatttct
     2401 cctaatgatt tagcaccata aggacctcct gggtcgaaat tctcagcaaa atctaccaat
     2461 atatttccaa cttctttttt tgtaggaact ttatactgta ggaaactatc tgttaataat
     2521 ctaccatctt tatcaaatat agggtcttca tacattgcaa accctatacc catcatcaca
     2581 ccaccttcta cttgtattct agctaaagtt ggatttataa ctgttccaca atcaggtaca
     2641 catgcaaaat ttatgacttt atattcgcct gtatttttat ctaattctat ctctgcaaat
     2701 cctgctataa atggttttat ttttttcaac atgccaaaag attctgttgc ttccaaaact
     2761 actggtacat catcactagc aaatcctatt cctccaacag attctctacc caattcctct
     2821 aatagaacaa acttgctatt atcgttttta acaaaaaccc tgtcttttcc caactctaaa
     2881 tcttcttttt taaatcctag ctttgactct gcaactgaaa gtaatatatc ttttaattta
     2941 tttgctgtct ttattgttgc atttcctgta accgttgtcg tacaagaagc aaatgctcct
     3001 gtatcatagg gacataagtc tgaatcacct gtataaatag aaattctatc tacagtagta
     3061 tttaaagctt ccgcagcaat ttgagcttga attgtatcag ccccttgacc taagtcagca
     3121 agaccagata atagtttata tgtgccatct tcatccattc ttatagtgac tgttgccata
     3181 tctacacgcg gtataccaga accatgattt gctactgcca tacctactgc tcttactttg
     3241 ttgtttccta tatctttaca tggatattta tcatcccaat taattaattt cttgcccttt
     3301 tctatacatt gtctcagctc acaacttaat atttcgtctt cagctgcttt tccattggta
     3361 tacctatcta ttatattttt aattctaaat tcaagtggat ccattccaat cttatgtgcc
     3421 aattcatcaa tagcactatc tattgcaaat attccctgtg tagcaccata ccctctaagt
     3481 gctcctgctg gtaacctatt agtatatact gttctagcat taaatctaac agcatcaata
     3541 tcattatata ttggtaaggt attgtgtcca gattcggaag aaacagagac accattccca
     3601 ccataagcac ctgtattgtt taatgacttt agctctattg cttttaaatt tccttcttta
     3661 tctgcaccaa ctttaacatc aaaaaacatt tcatgtctac tattagaacc tacaaaagtt
     3721 tcacttcttg taaatacaaa ttttgctggt ctaccagttt tcatagtaac aaatgcagta
     3781 aatatatctg ttgctgctat attctttcct ccaaatccac cacctattct aggtttaatt
     3841 actcttattt ttgaagatgg tatacccaat acttttctaa gtattctctt tacattgtgt
     3901 ggtgattgta atgatgaaac tacaacaatt ctatcattta tatctttata tgaatatgac
     3961 ctatgagttt ccatcatgca atgcgattga ctttgggttt tgtatgaaga ttcaaccaca
     4021 aaatcacttt ctttaagctt agcttcaaca tctccaaatt caaaaaattc ttttgatact
     4081 atattatttt ttgcatccaa tccaaaagga tatggctcta ctatgtcttt ttctggatgt
     4141 ataacaactt catttccttc tgcttctctt gcatcaaaca caggctttaa aacctcataa
     4201 tctaccttta tcatttttaa ggctttaagt gccgttttct catcttcagc agccactaaa
     4261 gctacttcat ctccaataaa tctaactgta tcttcaagta aaactctatc ataaggtgat
     4321 gcttctggtt ctgtttgacc tggcacacaa tatctgacct gtggtacatc tttatacgta
     4381 taaataccca caacccctgg aattttttcg gcttttgatg tatctatatt ctttatctta
     4441 gcatgagcat gtggacttct aagtagtttt aatgtcaaaa catctttatg cataatgagg
     4501 tcttcagtat atagaggttt tcctgtgaca attgctgtac tatctatctt tcttatcccc
     4561 ttattaatca ttatacattc cctcctcaat agcattatac atccttttaa ctaatgcact
     4621 tgccatatcc tttctgtact ctttactagc tctcatatta cttccataag taagttcctt
     4681 actagcaaca atagatgcct tatctatatc tttttcttta tttaatatat tactcgcttc
     4741 aagtgctaat ctagcttttt gaggtcttgc cccaattgct attttgtaag tatcattttc
     4801 ttttagcatt gctgaattta atacagaaaa atctcctgtg cattttctta ttgagtcaaa
     4861 aacagctatt gcatcttttt ttggtagtat tacttcgacc aatatatccc tacttaattc
     4921 actatccaaa aactcactta actctagtat tcctttattg tataatctca ccttcgctcc
     4981 aacaaccaaa agcgctggta ttaagtcaga aaagccatac tttgaaaata cacttgcacc
     5041 aattctagcc ccttgtctaa attgaacacc aactatatta gaaacagcgc ttgaaagtat
     5101 tccactacag taatttttta tagttttatc aatttctaaa cttctaagtg aagtatctgc
     5161 acctatcaaa atattttttt tatcctcttt tatataattt agatttatat cttttaaatc
     5221 tatcgctgtt cctatatttt tattacttaa ttttataaat ccacatccac ctaaaataac
     5281 attatttttt ttagaaatta aaattttata tgcttcttct aaactctgtg gaactgaata
     5341 ttcctttata gtaaccatct tatcccccca tcattaactt attaaaacac aaaagttttt
     5401 aataaatctt ttatttatat ttataattgt agtatattta attcacatat attaaacctt
     5461 tacattataa acttttattt ttatcctcaa ccttatcact tttatttcca ggaaatttta
     5521 ccatatataa agcttgaatt attatggcta ccattgctcc tgaaactaca cttgaatctg
     5581 caagtaatgt ctctataaat tttggaaatt tttcaagaac ttgaggagct accatgaatc
     5641 caataccaga agccatagaa agacctaata tcatgctatt ttcttgatta aatccatcca
     5701 tactaacaag tcttaaacca gatgttgtaa gagttgaaaa tataacgagt gttgctcctc
     5761 caaccacaca gggaggaatt gttcttatta aattagctaa taaaggcgat attcctgcca
     5821 aaaataatcc aattcctcca atagctagta caaatttact tacaaccttt gtattggaaa
     5881 cgattgcaga attttgtcca aacatcccca ttggagttgc agaaaataat gcacctattg
     5941 tagagagtac tccatttcct aaaacagcag aagaaagttc ttcatctgtt acttgtctat
     6001 taagccctcc taccgcagaa agtgtacaag cacccattat atcagctatc tcaactaaat
     6061 atattattga aaacattaca acaacttcaa gtcttatatc tagcccaaaa gcaagtggtt
     6121 ttggaagtgc aaccaaagta aactcctgaa ttgaagaaaa atttactata cccaaaatta
     6181 atgataaaat gtatccaaaa attatgctaa ctaatattga tgcatcttta aataatcctt
     6241 ttccatactt atttaatcct aatatcataa gagatacaga tattccaact ataaaattaa
     6301 ttggattccc aaaagtctca ttgcccatac ccccagctaa gttttttata gctattggaa
     6361 aaagtccaag acccatacat gcaactattg ttcctgatac agctggagta aatataaatc
     6421 gtattttttt aagaccaaaa ccaattataa ttattactat accagctatt atttgagagc
     6481 caaataatac tggtagtcca tacttacttg caacagatac cccagctcct ataaacatag
     6541 ctgtagctcc cattataact ggtattcctc ctcctaattt aaaaccttta aacaaaggta
     6601 ttggatataa ttgtaataaa gttgataatc ctgcaaaaac taatgcggct tgaatcaata
     6661 atgttgacat cttatgatta agtccagctg catttgcaat caatatcgct ggtaaacaac
     6721 tacctattac cattgccatt aagtgttgta accctaaagg tattgcttcc tttagtggtg
     6781 gtattccgtc taattcaaat tttgatgtac tttttgcttt cataataaaa actcccgtta
     6841 cataaaactt attgaattat ataaatactt aaaaatctaa tatattaaat taatgatgtt
     6901 cataaatatc aactatactc caacatatat ttaagttttt agtcttaaaa aacagatgca
     6961 ataaatttaa ttattaacaa atacacgtat tctttaattt tgtatacatt atataccatg
     7021 ctttacaaat ataagagtat tatagctatg aatttttaat tttttatagt aaatttaatt
     7081 caatttaaat ctttcaatct taatcattat aagttataag ttttcataag tatttacatg
     7141 tttcaagttt taaacattta cctataaacg ctactttata gatgtcactt caaatccagt
     7201 gacctcatac tttcatatga gcgtagacta tttcttcatc ttcagcatta cctgctaaga
     7261 gcaacccgtt tccactatca atcgcttata gtgtactctc tctcgagata gtcgtttgac
     7321 cttcctattt ctaggcttgg cgaccaaatg tccattttta agtacttagg ctctcaccat
     7381 ataccatcct cactattgtt tctggttttc accacattca taaaagtttc tttctatctt
     7441 ttattgtagt tgcaaggctt taggatttac tggttttaaa gttgtgtcct acatagattt
     7501 ctctatgtac ggggccaaaa gtacaattta tttaacatac tttgctttac cccctgtaaa
     7561 taatattatt tactctttca ctgtttttgt tattaaatta attaaatatc aattaatcta
     7621 agcataaaat aattatttaa tttaaactca aaatatttat gaatatttta taatataatt
     7681 ctcataagac agaaaaactt aataagctat gtatctcagt tgtaccaatg tactctcctt
     7741 tactatattt gtatctgcaa cataaaatat acaagtttct atctatttat agatatatat
     7801 atctataagc aaaatagtaa tattattttt atagtaaaaa ttttattcat attactattt
     7861 ataattttta tagagcaatt ttagtgccaa tatttgcata catttgtata gtataaaatt
     7921 tttatgttct cattgataaa attttactta tttcaagcgt tctattagat tttatcatct
     7981 aaattttagg ttttattttt ataaattaat tgtatttaca taaaaaaaaa gacctaaaac
     8041 aaatttttaa cggtcttttc tcaatttttt attttcattt ctaaaattta taataaatag
     8101 taagaacact ataaattctt ttatataaaa ttcttagttt gtggatgata aattagtgaa
     8161 ttaaaatact actttactga ttttagtttg acaatatcac tccaattttt actagtggct
     8221 aactctacta aatttaagtc tcttcttatt tcagctatat cctcttttat agaattagtg
     8281 tcacctttta tatatgctat gttatgttct atattatcat gagtagcttt atttatttca
     8341 gaattatgta ataaacttcc taaaatatta ttctgttcta tctgtatctc tttcattgat
     8401 ttatcttcac attctagact atcaatctta atttcaattc catataattt ttcatttgct
     8461 atggatacct cgtccttaat tccattcata tcttcattaa tgttatttat tttattttgc
     8521 ataaagttta cttctgattt aacttcggaa acatcttctt tcattacagt tatttcttgt
     8581 ctcacttctg acatgtcttt tttcattaca tttatctctt gttttacctc tgatgtatct
     8641 tctttcatta cggtcatttc ttgtcttact tcggacatat cttctttcat tatatttatc
     8701 tcttgtctta cttcggacat atcttctttt aatacattta tctcctgttt tacttccgac
     8761 atatcttctt tcattacagt catttcttgt cttacttccg acatatcctc tttcattgta
     8821 tttatctctt gtcttacctc ggacatatcc tctttcatta tatttatctc ttgtcttacc
     8881 tcggacatat cttctttcat tacaatcatt tcctgtttta cttctgacat atttcctttt
     8941 aatacattta tttcctgttt tacttccgac atatcttctt tcattacagt tatttcttgt
     9001 tttacttccg acatatcttc ttttaacaca tttatttctt gttttacttc cgacatatca
     9061 ttttttatgc taactacatc ttcatttata gtatataata actctaaaat cttctcttgc
     9121 acttgcatca ccatccctat taattattat aacattttac acaaatgcta tacaatgtta
     9181 acatatatat cagaattatt aaaattttaa ttaaacaaaa ttgattcact ttattacttc
     9241 aaaactaatt aatatctaaa ataactacaa ataaacaaaa ataaggtcaa caacaaaaaa
     9301 ggcttatctc tttgagatag cctttcttat ttttatttaa aactttgttt tttataaaat
     9361 aatctataca ttcagctctg aacatgaaat ttttcttcca agtgcttttg gtttacaaac
     9421 tgatatacaa agtccacaat atctacactc ttcttcattc aattccatct tatcattcaa
     9481 ttttctcgct tgatatgcac aaactctctc gcacatctta catttagtac atttttcttc
     9541 atcataagta aactcaaagc taagtctttc attaacatct cccatatgat tatgtactat
     9601 accacaagca ttttctatag tattatatcc taatctatta agattagatt ttaaatcatc
     9661 atgtatttta gatattactt gtgcgccttt taaaattact actgaacata taccaacaaa
     9721 gtcagcacct gccataatca tttctaaggc atcatctcca cttacacatc cacctaagcc
     9781 aattattggt atattaactt gtttttttat ttcatatatt ctctgtaaag ttattggctt
     9841 gatagtttct ccacttaaat atcctattcc atttccacct aataaaggtt gccctgtttc
     9901 tatgtctatt ctaaatgctg gtcctacaga gtcacaagca gttattgcat ctgctcctgc
     9961 ttcttctaat tttttagcaa aatcgcctat ctcatctatc ataggaggaa gtttaactat
    10021 tacaggtata tttactcttt cctttgcatc tttaagcatt ggtatcaaat ctctatagtc
    10081 ataagatact aattcaataa agtcagctcc tgcatttgca actttctcta ctaattcgct
    10141 actttcttca attgtatgac ctattgaagc tatacagaca gtcccatctc ttttcatttg
    10201 tggtatttca aaatctatcc attgctctgg ctcaaaatct gtccattttt cattatttaa
    10261 aagagcatta gctgtatttc taaccatatg tggtgctgga tttatagctc tttcttttct
    10321 tatagtctta gtcacaactg cccctgctcc tgcatcactt aatatcttgc atccagctgc
    10381 actatatgtt aatggtcctg aacctattat aagtggtgat tttaattctt tacctaaaaa
    10441 attatacatt atctgcttcc ccttttcata tatatttata ttcgttaaaa tttccaaaat
    10501 tcacaagcaa cttctttcat ttctttaaca atagcttttt tatctaaatc aactaactgt
    10561 ttttctttta aaatatgtct accatctatg tatacatttg atataaattc ttttttaccc
    10621 tgaactacta tctggtcaaa tatattatca agagtcacag gagttttaaa ttcatcttcc
    10681 ataactatta tatcagcctt attaccaact gctattttac cagaattttg aagtcctaat
    10741 acataagcac catgctctgt tgccattcta aatactaaat ttgctggcat tactgatgca
    10801 tcttcttcaa ctgatttatg cattaaaaat gcacctctca taacttcaaa aaaatcattt
    10861 atatatccat cagtacccag tgccactttt atgccttttt taatcatttt tggtactgga
    10921 gaaaaacctc cacctacttc acagttgcta agaggcatat gaactacttt tacacctttt
    10981 tcttttaata tatctatttc ttcatcattt acttttacac actgagatgc taatatagtt
    11041 tcatccaata tatctaaatc attatagtag tcaactgctt ttttgccaaa atgtttttca
    11101 gcatagtttg gctcatatat actctcacat aaatgaaatt gcattggtga atttaatttt
    11161 tttgcatctt ctttagcttt cttaataaat ctatcagaac atgtgaagct tgtatgtgta
    11221 cacattattc catttattaa tttactattt tctctactcc actttattaa attagaattt
    11281 tcatctaaac atctaagtcc attttcaaag cttattcttt cacaactttc taaggataaa
    11341 atcgctttca tgcctatttc ttctagtatt tttccttgct caattaaagt tccttcttct
    11401 gtatttggag cttctagggt atcacaaaaa gctaccacac cagattctat aagttctatt
    11461 gctgatgctt tagttgttgc cttcacttct ttcaatccaa ttctattttc tataaatggc
    11521 caccaatagt catttaaaaa accttcaaag tcagtaaaat gtacatttgc cggtattcct
    11581 ctagaaagaa ctccatattg atgcatatga ccattgacga atcctggcat tattatagca
    11641 tctgatttat ctattatttc ttcaatattt ttatatttta tttcaacttc ttcatttggc
    11701 aatatatctt ttataatgtc attttctact acaacagcag aatttgcata tatttcatca
    11761 gcagaagata ttaagtattt acttttaata gcaatcattt atttacctcc ctgatttaat
    11821 tttttcatgg ccatataaac tttctcagaa gttataggaa gttctcttat acgaactcct
    11881 gtggcattgt atattgcatt tgctattgct ggtgcaggtg tatgaataac tatctctcct
    11941 aaagatttag ctccatatgg acctgttggc tcataattat ctacaaaatc aacaattatg
    12001 tttcctatat ctttttttgt tggaactttg tattgtaata gattagaagt ttgaagcttt
    12061 ccatcagaac catgtctagg gtcttcatac attgcaagcc ctataccttg agttacacca
    12121 ccttcaactt gtattctagc aagtgcagga ttcataactg taccacaatc tgtagaacaa
    12181 gcataattta ttactttaaa ctcccctgtt gttttatcta actctatttc agcaaatcct
    12241 gctaagaatg gtttagcact ctcttgtata ccataagatt cagatgaata taaaacttct
    12301 tgatttccac caccaacaga ttcttttcct aattcactta acaaaacaaa cttctctaca
    12361 tcttcactat aacaaactct gtcttcatat agtattaaat catctattgg taaatcgagt
    12421 ttcttctgtg ctacttttaa tatcttttgt tttaaacttt cagcagattt tattgtagca
    12481 tttccagtta cataagtagt acaagaagcg tatgcaccag tatcatatgg acacatatct
    12541 gtatctcctg tataaacgga aattctatca atagatgtat tcaatgcttt tgcagctatt
    12601 tgtgcaagta ttgtgtcaga accagttcct aagtctgaag acccagaaaa caacttataa
    12661 gttccatctt catccatcct catatttact attgccatgt ctatgttggc tataccagaa
    12721 ccatgagttc ccacagacat tccaacagcc ctcaccttat tgttgccaat atccctaaca
    12781 gggtactttt catcccatcc aataagtttt ttacctctaa ttatacattc atcaagtgca
    12841 caacttctta ttggaaaatt cattattccg ccttcagttt gtttttttat aatattcttt
    12901 aactttattt ctgttgggtc catattaagt ttatgcgcta attcatcaat tgcacaatca
    12961 agtgcaaatg taccttgtgt tgctccatat cctcttaatg ctcctcctgg aactaaatta
    13021 gtatatacag ttctcccatc aaattttatt gcaggtacat tattatatgt tggaagtaca
    13081 ttatgacctg attcagagca aactgaaggt ccattatcac cataagcgcc tgtattgttc
    13141 aatgctttca tatctatagc ttttatgttt ccttctttat ctgccccaat ttttatatca
    13201 aaaaacatct gatgtctagt attagtcatt gcaaaagttt cttctctagt ataaattagt
    13261 tttgctggtc tttttgtcat ccaagttaca aatgatgcat atatctctgt tacagctatg
    13321 ttttttccac caaaacctcc acctattctt ggttttatta ctctcacttt tgaaagaggt
    13381 attcccagtg ctttagaaac ctgtcttctc atatgataag ctgattggtt tgcagaagtt
    13441 actactaatc tgccattcgt atctatatac gtataagctc tatgagtttc catcatacaa
    13501 tgggcttgtg attgagtcat ataagaatgt tctactatta catcactttc tttaaactct
    13561 ttttctacat cccctttacc cattttttct ctcgatacaa tattttttgt agcatccaat
    13621 ccaaaatcaa atggacaaaa caaatcatct tcttcatgga ttaaaatttt atttccttcc
    13681 gattctcttg catccaatat aggagtcatt acttcatatt caacttttat aagtttcata
    13741 gctttaatag cagccctttc atcttcagcg gctattatag caacttcatc tcctacatat
    13801 ctaactacgt cttcaagtat taattggtca tgaggtgatg cttctggata tgactctcca
    13861 accattgaat atctataatt tggaacatct ttgtaagtga atatgtttac tacacctttt
    13921 acctttaatg cattttttat atctatgttt tttatcttcg caaaagcatg tggacttcta
    13981 agaagcttaa ttgttaaaac atctttatga aaaattaaat cttctgtata tattggtttt
    14041 ccagtaacaa tggcttcact atctattttt cttacctctt tatttaccat cacactcacc
    14101 tccaatacta ttatacattc tcactactaa ggcttttgcc atatcttttc tgtattcttt
    14161 acttcctctt atattacttc caaatgaaag ttcttcactt gatacttcac cagctttttc
    14221 tatatcattt tctaaactta atatttcact tgctttatag gcaatttttg ctcttcttgg
    14281 tctagcgcct attgcaattt tataaatact tccttctttt aacattgctc catttaatac
    14341 tgcaaaatca cctgtacatt ttcttataga atcaaataca cctatagcat cttttttagg
    14401 taatataact tctattaata tatctttttc aagctcactt tctaaaaaat cagctaagtt
    14461 cataacccct tttttatata acttaacctt tgcatctacc actagtaatg aaggtattaa
    14521 atctgaaaat ccatacttag caaatacgct agctcctact ctagctccac ttctaaattg
    14581 aactcctact atattagaaa cagcgtttga aattacccca ttacagtaat ttttaataac
    14641 cttatttaat tctaaagttc ttaaacttgt gtctgctcca attaatatgc tatcatcagt
    14701 ttcatttata taatctaaag ctaagtcttt taaatctatt gctgatccaa tatttttact
    14761 acctagtttt aaaaatccac atcctccaag tattatgttg ttttttcttg atattagcag
    14821 ttcataagct tcatctaaac tttttggaac tacatattcc tttatagtta tcatactctc
    14881 tccccatatc aacttaattt tcacttaaaa gtctaagtgt ttaaatattt atgtattgct
    14941 cttaattgac ctttatatcc tgtacatcta caaaggttac catttacata atctataact
    15001 tcttcttctg ttggattttg aagctctctt ttcattgcca aaaccatcat tataaatcca
    15061 ggagcacaaa atccacactg gtcagcccct tcgtctgcaa gaaaatctcc aaacttcttt
    15121 gcttcatcca agacaccctc aagtgttgta atatgctgac cgtctactct agcagtaaga
    15181 taattacatg aaagcacggc cttgtcattt accatcactg tacataaccc acatgagcct
    15241 gtatcacacc cttttttaac acttacatat ccattttctc ttaatgtatc tgctaaaaaa
    15301 tcatctggtc ttatacttaa ttctttttct ttattattta tggtacattt gataatcaaa
    15361 taaatcacct caaaactcat atttttaagc taaagtttta ctatactttt ctatgaataa
    15421 attacattta ttaataaagg ctattccatt tatgaccttc cattctattt tttatagttc
    15481 ctcttacaca aagtctctca gctgtatctt gagcatcttt taatgctttc tcttcattag
    15541 ctgtcaatat ttttgaatct tccattatta tatttccatc tactataaca ctctctatat
    15601 ttttcatact agaagaatat actaatgtag atactggatt atgcataggt atcgcttttg
    15661 gtgaaagcat tggattaaat attagtaagt ctgctttttt acctatctcc aatgaaccta
    15721 tctcatcttc cattccaata gctcttgctc catctatagt tgccaactca agaacttttt
    15781 ctgctgacat tgctaatggg tcacacttat taactttatg ttgaagtgct gttaatttca
    15841 taagttcaag catatcttga gagttattac tagcggctcc atctactcct aaactaactg
    15901 ttattccttt tttaagcatt tctggcactg gtgcaacacc tgaagataag tacatattac
    15961 ttgctgtatt atgagacact ttcatatcgt attttttagt aagttccata tctttttcag
    16021 ttagatacac acaatgtacc ataagcacat ttggtccaag tattcctaat ttttctaaaa
    16081 catctatgtc atattgccca tgcaattctt ttgctgcttc tctatcaaaa ggagtctctg
    16141 atatatgtac tgtaaataaa gcatcatcat attcttttac tactctccat agcatttcaa
    16201 gcatttcttg agaatttgac catattgctg caggagctac tcctattttg attcttccat
    16261 tttctgtatt atggtgtttt tcaaacaatc ttcttacatc tttttcaacc gtttctacat
    16321 cttgcattat tccaggatga actccaaatt gagctcctgt attcatacat cctcttccaa
    16381 gtattcctct tattcctaat tctttataag catctattat tccatcacaa agacctggct
    16441 tactatgagg atacatgtag tcaaccattg ttgttatacc acttctaagt ccttcaatac
    16501 atccaagcat tgcagcatca taagtatctt tgggctctaa atagttagct gctggaaatg
    16561 tcatagtttc taaccagtct ttaagtacca tatcatctcc caatcctttt aataaagttt
    16621 ggaataaatg attatgtgta tttataaaac ctgggaataa aactttacct ttagcatcta
    16681 taattttttt aacatcagta tatttacttt ctatctcttt agaatttcca atatcagcaa
    16741 tcttgttatc ttttactact aatgccccat caaaaataac ttctctctct ttattcacag
    16801 ttactattat ggcattctta ataagtatat ccatcattct tatttccccc cgcattattt
    16861 agtaattttt cttttaatat attgacctgt tggatgttct ttaacattac aactttgtac
    16921 tacatgattt cctctcaaaa atacatcttc aactttacat ttaaccttaa atccttcata
    16981 tggagtataa tctacatttt gtttttgagt tttataacta attgtttctt ctttattgat
    17041 atttaaaatg actatatctg catcacttcc tacagctatc tcaccttttt taggatacat
    17101 tccaaatatt tttgcagcat tcgtagaagt aacttccaca aacttattta cacttattct
    17161 attttctaag accccatatg tatataaaag tgctaaccta tgttcaacac caggtgctcc
    17221 atttggaatc ttactaaaat catcaattcc caagtctttt tgccccttaa aattaaatga
    17281 acagtggtct gtgccaactg tttgaatatc tccactagac aatccttccc aaaggtaatt
    17341 tatgtcttct ttttttctta aaggaggaga cattacatac ttagcaccct caaatttatc
    17401 cttattatat aaattgtctt ctaataatag atactgtggg catgtttcta ctatcatatc
    17461 tatatttttt tctctagcca tttttacagt ttcaagtgac tccctacaac ttaagtggac
    17521 tacataggat tttgaattag ataatttagt tatatcagca agtcttgaaa cagactcttt
    17581 ctcaactatg ttaggtcttg taagtggatg atattttggc tctaaattac cattttgtat
    17641 attttcttct atcaatacat ctagtaaatc cccattttca caatgaaatc caactataca
    17701 acctaaatcc cttgctttct ttaaaaccct gtatattgtt ccatcatcta ctttcatgcc
    17761 atcatatgcc atatacatct taaaagatac tatcccatcc gaaataagtt tttccatatg
    17821 attaaatgta tctttattta aacatgtaat tgtcatatga aaaccataat cacaataaca
    17881 atttccactt gcttttttat gatatgcttc tacaccttgc agtaggtctt ccccctcatt
    17941 ggcttctgca aaatctagta ttgtagtagt tcctccagct atagctgctc ttgttcctgt
    18001 ttcaaaatta tctgcagttg taatagaacc tgcattcata tcaaaatgag tatgtgtgtc
    18061 tattccacca ggaattacaa ttttacctgt agcatcaata accttatcac catttatttc
    18121 taagttattt cctatttcaa ctattttttc atcttctatc cttaaatcac ttatataagt
    18181 cttatcagag gtaattatag ttccacctct tagtattgtt cccatatata cctcctaact
    18241 tttaagcttt aaagtatttt ctaagtattg taaaacttta tttaaaattg tattttctaa
    18301 aggtgctata ttcagcacct ctagactata tttaaataat ttattgtgaa ctaaatatta
    18361 ttttccgtat acagatttta atattccata gtaaccttct gttcctataa ataactgttc
    18421 ttgctctata tactcatcta ttgtgtgagc aagattttcc ttagaaggac caaatcctat
    18481 agtttttatt ccagcttcac ctgcatagtg acttccattc gtacaaaatg agtattgagt
    18541 tatttctgaa tctattccag cttcttttaa tcccttatat gctgcttgaa caaattcatc
    18601 ttcttcgtca tataaccaac ctgggaagaa tctttcactt tctatagtat ttcctgtata
    18661 gcaatcagct ttttcaac
//
LOCUS       DAMKNB010000072        17423 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.076, whole genome shotgun sequence.
ACCESSION   DAMKNB010000072 DAMKNB010000000
VERSION     DAMKNB010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 17423)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17423)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17423
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.076"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            complement(102..722)
                     /locus_tag="PC494_002753"
     CDS             complement(102..722)
                     /locus_tag="PC494_002753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HDF3913244.1"
                     /translation="MQYIQELLDLTQNYWVLATIIGLLSAFIESFIPALPLVAIVTAN
                     AAIQGLFIGCLLSWIGSGLGTTSLFLLISRFNDSKLFNKLRNSKTEKAISWMDKQGFK
                     LLFIAYACPFMPGCLVTIASAFGKKDLKDFVPAMLAGKFVMFIVISYVASDIEGFITS
                     PLKIASFILLVFLSWKIGNRVNKNLENHNYDFHHKKHHNDKDDKMI"
     gene            complement(1036..3174)
                     /gene="vanT"
                     /locus_tag="PC494_002754"
     CDS             complement(1036..3174)
                     /gene="vanT"
                     /locus_tag="PC494_002754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021418922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine racemase VanT catalytic subunit"
                     /protein_id="HDF3913245.1"
                     /translation="MIRNKSYAGLDYFRIIAALLIIAIHTSPLLSYSKMADFVLTSII
                     ARIAVPFFFMLSGFFLISTYNYNCNKLKSFLKNVLFIYGIAIVIYIPLNIYTGYFSMN
                     NLVPNIIKDIVFDGTLYHLWYLPASIIGASIAYFLVKKLGLKYSLVITIVIYVIGMFG
                     DSYYGFLEKIPLLKNLYGYIFEVSDYTRNGIFFAPVFFILGGIISNKSNYMSTKNSLI
                     GFLISFLLMLCEGMFLHKLGVQRHDSMYIMLLPCMYFLFTALTFLKGSRARLLRTSSL
                     IIYIIHPMMIVVIRMFSKIFGIQTVLVDNSLIHYIVVSIASFIASIIIILILKPIKKD
                     LKGEHKVNTNRAWIEIDLNNLEHNVKMIQKAMPEDCELMAVVKANAYGHSAFEVATCA
                     NQIGVKAFAVATIDEGIDLRRYGILGEILILGYTNPIRAKELHKYNLTQSVIDLNHAI
                     SLNKQKYNIKSHIKIDTGMHRLGFDVNDVRSILKAFKLKYLDICGIFTHLCVSDSLKD
                     EDVDFTNKQIECFYKLIDFLLKKGIKIPKVHIQSSYGFFNYPNLKCNYVRIGIALYGI
                     LSSPNDTTKLQLDLRPVLSLKSQVILIRKIQKDDSFGYGRVFIASRDSVIAILSIGYA
                     DGIPRNLSCGKSYVIINGCRAAIVGRICMDQLAVDITDIPNVEVGNTAIIIGRDNLSE
                     LSASEVANNSCSISNELLSRVGRRLNVIKK"
     gene            complement(3192..3998)
                     /locus_tag="PC494_002755"
     CDS             complement(3192..3998)
                     /locus_tag="PC494_002755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HDF3913246.1"
                     /translation="MMNNILLDKNKEDKMTNTILLTKDKVYDGNLILVNAFLPVKTSE
                     DIDLIPVDTRFPSILMKREATNILQNILKSICGINEIVPVSGYRTAEEQQDIYSSSLR
                     DNGKDFTKKFVALPNHSEHQTGLAIDLGLKKEVIDFICPEFPYNGICNEFRKAALHYG
                     FIERYQCKKEEITGISQEPWHFRYVGYPHSEIINKMNLALEEYIEYIKRFSYTNCLKI
                     EDKEKIIEIFYVPIHTKEEVRISIPEQCVYQISGNNKDGFIVTFWRNRKD"
     gene            complement(3995..5095)
                     /locus_tag="PC494_002756"
     CDS             complement(3995..5095)
                     /locus_tag="PC494_002756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021418924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HDF3913247.1"
                     /translation="MNNKKIAVIFGGNSTEYDVSLQSAFAVLENLNTEKYDIIPIGIT
                     REGNWYHYIGDYNNIQNNTWFERDTDIIPVIVSQNRVKNGIIEFLISDAVSQNHIPNS
                     AIESCENDIKYTKLDFVFPILHGKNGEDGTVQGLFELAGIQVIGCGTLSSALCMDKDK
                     SHKLVHSEGIKVPKSILLKYSDKFNVAELSKDLTYPLFIKPVRAGSSFGISKIYKKEE
                     LQVAVDLAFEHDNEVIIEENIDGFEVGCAVLGNDDLLVGRVDEIELSKGFFDYTEKYT
                     LKSSKIHMPARIDLDCEKRIQETAKIIYRTLGCSGFARVDMFLTPSGEIIFNEVNTIP
                     GFTSHSRYPNMMKGIGLSFEEILDKIIEVYIK"
     gene            complement(5365..6438)
                     /locus_tag="PC494_002757"
     CDS             complement(5365..6438)
                     /locus_tag="PC494_002757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HDF3913248.1"
                     /translation="MRTALMAFIAIIFIWILYSFILYGKFSIWIVSFFENAFRMEYKA
                     ALNLYQQIFRNSMELFMILAMVIVFFIIFRVYLNWFTKYFSEINQGIDSLIKEDVGEV
                     ALSPELLAIEKKINSIKHILEQRKFETQMAEQRKNELIVYLAHDLKTPLTSVIGYLTL
                     LRDESQISEELRKKYLSISLDKAERLEDLINEFFEITRFNLSNISLEYSTVSLTRMLE
                     QLTYEFKPTLMSKNLKYTLNVTPNMMIRCDVNKMQRVFDNLLRNAVYYSFEDTTIEIT
                     AVQEDDYIKLKFMNHSNTIPEEKLERIFEQFYRLDTSRNSNSGRAGLGLAIAKEIVEL
                     HNGTITAHSENNIITFKVIIPIV"
     gene            complement(6488..7189)
                     /gene="vanR"
                     /locus_tag="PC494_002758"
     CDS             complement(6488..7189)
                     /gene="vanR"
                     /locus_tag="PC494_002758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021418928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanR-ABDEGLN family response regulator
                     transcription factor"
                     /protein_id="HDF3913249.1"
                     /translation="MNENILIVDDEKEIADLIEVYLKNEGFTVYKFYTGKEALECIES
                     KDLDMAILDIMLPDIDGFHICQKIREKYYYPIIMLTAKIEDIDKIMGLTIGADDYITK
                     PFNPLEVVARVKTQLRRYMRYNNSYEQQSIIVNEYDIKGLIINKETHKCSLFGKEVAL
                     TPIEFSILWYLCEHQGKVVPSEELFEAVWGEKYLDNNNTVMAHIGRLREKIHEPSKNP
                     KFIKTVWGVGYTIEK"
     gene            complement(7623..10154)
                     /locus_tag="PC494_002759"
     CDS             complement(7623..10154)
                     /locus_tag="PC494_002759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HDF3913250.1"
                     /translation="MSLKSLKIKENLYWVGSLDPDLRVFDIIMYTPYGTTYNSYVLKG
                     TEKTVLFETVKDKHFDNYIERLNDLNIDFEKIDYIVVSHTEPDHAGSVEKLLDLAKNA
                     KVVASETAIKYLKEIVNKDFEYVAVTDGDTLSIGDKTLEFFSVPMLHWPDTIYTYIKE
                     DKTLVTCDSFGSHYSNDKIVNTLDENEEKDYLDALRYYYDCIMGPFKPSMVTAIEKIK
                     DLDIDTVCPGHGPVLTENPRKIIDLYYNWSVNEQIKLEKEVTICYVSAHGYTKIMAEA
                     IKAYIEKNSNYKVNLFDVIEHKQEDILAKIAVSQGVLFGTPTILGDALKPIWDILISL
                     NPVLHGGKVASVFGSYGWSGEGIENAMERISQLRMTAVKPFAVNFKPSNEEIDKLHSY
                     TGKFLDKLNSTFGSKKKTKKFKCVICNEVFESDSAPSVCPVCGAKEDQFIEVEEDEVT
                     FRKDTDEYFVIIGNGAAGFYAADAIRKRNKTCKITMISNEDELTYYRPALSDGINEEL
                     GSDFYMEDKDWYDKNNIVVILGTNVDKLDEVNKTIIVNDGAIKFDKLVIATGSRNFIP
                     PIKGHDLENVFTLRNIKDLYSVKEALEKSKKVVVIGGGLLGLEAAWEFRLKGLEVVVV
                     EAMDSILSKQLDKEGSKILEQCVRDTGIDVRLGVAVDGIEGDGKAQKVVFKDGDSVDC
                     DMVVFSIGVRANTQMVQDTSVKIDRGIVVDKTLQTNIKDIYACGDVAQVGNISLAIWP
                     SSVEMGKIAGANASGDNLTFESEVYPVSLDAMNVKVFSIGNIQNFDKEISSKDEGQRI
                     YKKLFMKDGSLVGAILINDLSCTVKLIRLISEKGDFEDIMKADIL"
     gene            complement(10262..10879)
                     /locus_tag="PC494_002760"
     CDS             complement(10262..10879)
                     /locus_tag="PC494_002760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HDF3913251.1"
                     /translation="MCKKTYLLVVSMLIAGLLTACSGSPTKDSGQAQDNTKKEANASN
                     NALKDEKNNENLMEQDFKVPYTDAINIFKDKYKDADIVDLSLERDLNKFVYTVEGVDD
                     NNEYKMKIDANTKDVLEDKTEKLDSEDLNGVARKEKLDLNDIMTPQQAMEIALKEQNG
                     IVKEWSLDKDLDVTFYKIRIDKDKNEYDIKVDSKKGTVLKVEKED"
     gene            complement(11241..12125)
                     /locus_tag="PC494_002761"
     CDS             complement(11241..12125)
                     /locus_tag="PC494_002761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel"
                     /protein_id="HDF3913252.1"
                     /translation="MDTTKIDDISKLDLNNLDINKMDMGGIMESLLEWATTSGVKLII
                     GILILSIGFKIIKKFVNHVMLLLSKRDIDLTLRKFLKSLLLSVLKVAVIIIVLEYWGM
                     SLSSFAAVIASAGVAIGLALQGSLSNFAGGFIILLIRPFKVGDYVEAAGHGGTVEQIG
                     LFYTQLVTPDNKQILIPNGSVSNDSLINYSAKNTRRVDLTFSVGYEDDILHVRRVLKD
                     IVNNHKLIINEPEPFIGVVEHGDNAIKFATRVWCKTEDYWTIYLDLLEEVKVRFDEEG
                     ITIPYPKMDLTVKELNKI"
     gene            complement(12316..13566)
                     /locus_tag="PC494_002762"
     CDS             complement(12316..13566)
                     /locus_tag="PC494_002762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDF3913253.1"
                     /translation="MKSYTKAKWSVWGIITFSFVLVLFLRMSTAVVSDNLANELGFNS
                     IQISNIASFCLYAYAFMQIPAGILIDKYGARKISSLGIIMASLGSILFGLIQSIELAY
                     ISRVIVGAGTSVILLCILKIQGRWFNKSEFASATAKFSFVGNLGGVLATFPLVFLSEL
                     VGWRNSFLLIGIIGVVIGCFMYIIVRDTPKEYGFNVDTEPYEKSEKVNIVDGIKSVIK
                     NKSTWYNSMIMFSFVGLTSAFISLWGVRYIMDVYGVSKSFSAFIVSFFTYGFIFGSII
                     MDFVFAKIRSSKFNIIKFGAMIDLFIWIVIVVVYQVKPPIIVLPISFFIMGCIVMSHL
                     QVFNDAKYKNKEIYSGLATSVINTFEFIGSGIINLIIAISLQVNSYNIVDGYKKGFVV
                     FIVLSIITIVSSHIGVKNDDFKAI"
     gene            complement(13788..14552)
                     /locus_tag="PC494_002763"
     CDS             complement(13788..14552)
                     /locus_tag="PC494_002763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF3913254.1"
                     /translation="MLGKLLKYELKASGRIFIPLYIAILIVAVFNGIFMNTNILQVQG
                     IGILVLTSLFMALGVLTIVVTIQRFRKNLLGDEGYLMFTLPVSTSSLILSKCITALIY
                     AVLSFIVAVFTFGVLMLFGTSGILLPEILDLFNTSFKWISENFLDILLLVVVMFISYS
                     SFILLLYTSISMGQLPKFNKHRNIVAFASFIAINIVISIVGDAVGSILPNEDTNMVYH
                     LYQSPSFMLAILGSLVVAIALFFATKFILDKKLNLE"
     gene            complement(14546..15271)
                     /locus_tag="PC494_002764"
     CDS             complement(14546..15271)
                     /locus_tag="PC494_002764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF3913255.1"
                     /translation="MDKNISNVSQDGIVEFKGVNKSYGTKNVLKNIDLNIPKGKIVGL
                     LGPNGSGKSTMIKLMNGLLQPDNGEIMINGMKPSIDTKKIVSYLPERTYLNDWMKVSD
                     LLKFFYDFYSDFDVRRANEMIKSLDIDVNEKLKTMSKGTKEKVQLILVMSRNASIYIL
                     DEPIGGVDPAARSYILKTILKNYSEDSTLLIATHLISEIENICDEIIFISKGEIVLQG
                     DVEAIREEKGKSIDALFREEFKC"
     gene            complement(15273..15641)
                     /locus_tag="PC494_002765"
     CDS             complement(15273..15641)
                     /locus_tag="PC494_002765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDF3913256.1"
                     /translation="MEWELDNNKPIYIQLVEHLKLKIISGEIKIGSKLETVRALAEDA
                     EVNPNTMQKALTELERQGLVYSQRTKGRFVTDDKEKIKAMKEEIANVEINTLKVTLEK
                     LGYDRDEMLKLITENLKGEL"
     gene            complement(15817..17361)
                     /locus_tag="PC494_002766"
     CDS             complement(15817..17361)
                     /locus_tag="PC494_002766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional diguanylate
                     cyclase/phosphodiesterase"
                     /protein_id="HDF3913257.1"
                     /translation="MRNLQKKLMFFLFICIILQITYTTPVYSLCKLYKNNSINNFESI
                     VSNNQLISKHAIQIILIMAIICVILIFYIIYDKLNFKIKLQRIAYTDNLTGANTIDKF
                     VIDANKILCKNTQVKYALLYIDIDKFKYINDLFGYEVGNEILRNLTKIIKRNIFEEEM
                     FARISADNFIIIMKYIEEEDITKRLKTIFEELDLFNNNQEEKYKLVLSCGIYFILPED
                     RDINSIIDRANIPHKMAKGGHKSSYAFYDNKIHDQEIKEKEMENTMFSSLENKEFIIY
                     LQPKIELNTGEIQGSEALVRWKRPDKGLIPPNEFIPFFERNGFVINLDLYVLEEVCIY
                     LRKWIDAGINPVTVSVNVSRIHLYCNNFIETYKNIIDKYNIPAKYIELELTESIIFDN
                     FDILIDIMNNLKKIGFLISMDDFGSGYSSLNMLKEIPMDILKLDQKFIMETYNSKRSK
                     IIVTKVIEMAKELGMKVISEGVETEEQFKLLKEVKCDMAQGYLFGKPMPIEEFEHLIV
                     SNLVRG"
BASE COUNT         5982 a         3072 c         1743 g         6626 t
ORIGIN      
        1 acaaaagaac taaaaatttt gtaccttaat acaaaaaata aaacgtatct taaaataatt
       61 tagtactaaa tcattttaag atacgtttta tttcgtacaa gctaaatcat tttatcatct
      121 ttatcattgt gatgtttttt atgatggaaa tcataattat gattttcaag atttttattt
      181 actctatttc caatcttcca tgacaaaaac accaataata taaatgatgc tatctttaaa
      241 ggacttgtta taaaaccttc tatatcactt gccacgtaac ttataactat aaacattaca
      301 aattttcctg ccaacattgc tggcacaaaa tcttttaaat cttttttacc aaaagctgat
      361 gcgatagtaa ctaaacaacc aggcataaat ggacaggcat acgctataaa taataactta
      421 aatccctgtt tatccatcca acttattgct ttttcagttt tactatttct caacttatta
      481 aaaagcttac tatcattaaa tctgcttatt aataagaata atgaagttgt cccaagtcct
      541 gagccaatcc atgataacaa acatccaata aataatcctt gtattgcagc atttgctgta
      601 actatagcaa caagtggtaa ggctggtata aagctttcta taaatgcact taataagccg
      661 attattgtgg ctaacaccca ataattttga gtcaaatcaa gtagttcttg tatatactgc
      721 atattgcttt tccccttttt taactttaac tattattata tactctatat gtttattata
      781 taccaatctc aaaaaatgaa tctaatatta aaaagtaaat aatctatata agtttacagt
      841 taaggtataa ttattttatt atatattata acaaaaaagg tgatgtttca aaataaaaat
      901 ctgaaacatc acctttttat agcttaaatt gtcatgtaag ttataaaaaa tatatattag
      961 acataatatt actaaaaatg tctagtcaga gtaaaataaa ttacacagta caacaaatat
     1021 tactatttaa ttgagttact tctttataac atttaacctc cttcctactc tgctcaataa
     1081 ttcatttgat atactacatg agttatttgc aacttcagaa gcagataatt cagataaatt
     1141 atctcttcct attattattg ccgtattacc aacttctaca ttaggtatat ctgtaatatc
     1201 aacagcaagt tggtccatgc aaattcgacc cactattgct gctctacaac catttattat
     1261 tacgtaactt tttccacagg ataaatttct aggtatacca tcggcatagc caatagataa
     1321 tatagcaatt acgctatctc tgcttgcaat aaagactctt ccatatccaa aactatcatc
     1381 tttttgtatt tttctaataa gaattacttg tgattttaag gataaaacag gtcgtaaatc
     1441 aagttgcaat ttagtcgtat catttggaga acttaatatc ccgtataatg caattccaat
     1501 tcttacataa ttacacttaa gattgggata attaaaaaaa ccataactac tttgaatatg
     1561 tactttagga atttttatac ctttttttaa cagaaaatca attaacttat aaaaacattc
     1621 aatttgttta tttgtaaagt ctacatcttc atctttcaga ctatctgaaa cacacaagtg
     1681 tgtaaatatg ccacatatat ctaagtattt taatttaaat gcctttaaaa ttgacctcac
     1741 atcattaaca tcaaaaccca gtctgtgcat acctgtatca attttaatgt gtgattttat
     1801 gttgtatttc tgtttgttta aagagatagc atgattaagg tcaataacac tctgtgtaag
     1861 attgtattta tgaagttcct ttgcccttat tgggttagta tatccaagaa tcaatatttc
     1921 tcctagtatt ccatatcgac gtaaatcaat cccctcatct attgttgcta ctgcaaatgc
     1981 ttttacacct atttggtttg cacaagtcgc tacttcaaaa gcactatgac cataggcatt
     2041 agcttttaca actgccatca attcacaatc ttctggcata gctttttgta tcatctttac
     2101 attatgttcc aaattattta aatcaatttc aatccaagct ctattggtat ttaccttatg
     2161 ttctcctttc aagtcttttt ttataggttt aagaatcaat ataataatta tagaagctat
     2221 aaaagatgct atacttacca ctatataatg aataaggcta ttgtcaacca agacagtttg
     2281 tattccgaat attttagaaa acatacgaat aacaacaatc atcataggat gtataatata
     2341 aataattaat gatgatgttc gcaataacct agctcgagaa cctttcaaaa atgttaaggc
     2401 tgtaaataag aaatacatac atggcaataa cataatatac atgctatcat gacgctgtac
     2461 ccctagttta tgtaaaaaca ttccctcaca taacataagt aagaatgata taagaaatcc
     2521 aatcaagcta tttttagttg acatataatt agatttatta gatattattc caccaagtat
     2581 gaaaaataca ggtgcaaaaa atataccatt tcgtgtataa tctgatactt caaaaatata
     2641 cccatataaa ttctttaata gtggtatttt ttctaaaaaa ccataataac tatcaccaaa
     2701 cataccaatt acataaataa caatagtgat tactagtgag tactttaaac ctagtttttt
     2761 tacaagaaag tatgcaatac ttgcaccaat aattgatgca ggaagatacc ataaatgata
     2821 taaagtccca tcaaatacaa tgtccttaat aatattgggc actaaattat tcatggaaaa
     2881 atatccagtg taaatattta agggaatata aattacaata gctatcccgt aaataaataa
     2941 tacatttttt agaaaagatt tcagtttatt acaattataa ttatatgttg aaattagaaa
     3001 aaagcctgat agcataaaaa agaatggcac agcaatacga gcaattatac tagttaacac
     3061 aaagtcagcc attttactat atgataataa tggagatgta tgaattgcaa ttataagtaa
     3121 tgcagctata atcctaaaat aatcaagccc tgcataagat ttattcctaa tcattcttgt
     3181 tcctccattt cttagtcctt tctatttctc caaaatgtca caataaaacc atccttattg
     3241 ttacccgata tttgatatac acattgttca ggtatagaga ttctcacttc ttctttagta
     3301 tgaataggta cataaaagat ttctataatt ttttctttat cttctatttt taaacaattt
     3361 gtatacgaaa atctcttaat atattctata tattcttcaa gagcgagatt cattttattg
     3421 ataatctcag aatgcggata tcccacataa cgaaaatgcc atggttcttg agatattcct
     3481 gttatttctt cttttttaca ctgataacgc tctataaaac cataatgtag tgctgcctta
     3541 cgaaactcat tacaaatacc attataagga aattcagggc agataaaatc tataacttct
     3601 ttctttaacc ctaaatcaat agcaagccct gtctgatgtt cactgtgatt tggaagtgct
     3661 acaaactttt tagtaaagtc ttttccattg tcacgcagag aacttgaata tatatcttgt
     3721 tgttcctctg cagtacgata tccacttaca ggtactattt catttattcc acatatactt
     3781 tttaaaatat tttgtaaaat gtttgtagct tcacgtttca taagaatact tggaaacctt
     3841 gtatctacag gaattaaatc tatatcttca gatgttttaa ctggtaaaaa agcatttact
     3901 agaattagat tcccatcata aactttatct ttagtcaata agatagtatt tgtcatttta
     3961 tcttctttat ttttatctaa taaaatatta ttcatcattt tatgtacacc tcaattatct
     4021 tgtccaatat ttcttcaaaa gacagtccaa tacctttcat catatttgga taacgactat
     4081 gagaagtaaa gccaggaatt gtattgactt cattaaaaat aatttcacca gatggagtta
     4141 aaaacatatc cactctagca aatccagaac atccaagagt tctataaata atttttgctg
     4201 tctcttgtat tcttttctca caatccaaat caattctagc tggcatatga atttttgaac
     4261 ttttcaatgt atatttttct gtataatcaa aaaatccttt tgacaattct atttcatcta
     4321 ctcttccaac aagtaagtca tcgtttccta aaactgcaca ccctacctca aaaccatcaa
     4381 tattttcctc aattattact tcattatcat gttcaaaagc caagtctact gctacttgta
     4441 actcttcttt tttataaatt ttactaatac caaatgatga acctgcacgc acaggtttta
     4501 taaataatgg ataagttaag tcttttgaca gttcagccac attaaattta tctgagtatt
     4561 ttagtaatat tgattttggt actttaatac cttctgaatg aacaagttta tgtgatttgt
     4621 ctttgtccat acataatgct gaagaaagag taccacatcc aataacctgt atacctgcca
     4681 attcaaataa cccctgcact gttccatctt ctccattttt tccatgcaat ataggaaata
     4741 caaaatcaag tttagtgtat ttaatatcat tttcacatga ttcaatagca ctatttggaa
     4801 tatgattctg agaaacagca tcagaaatta aaaattcaat aataccattt ttgacacggt
     4861 tctgcgaaac aataactgga attatatcag tatccctttc aaaccaagtg ttattctgga
     4921 tattattata atctccaata taatgatacc aattaccctc ccttgtaatt ccaattggta
     4981 taatatcata tttttccgta ttcaaattct caagtactgc aaaagctgat tgtaatgata
     5041 catcatattc tgttgagttt ccaccaaata taactgcaat ttttttatta ttcatctttg
     5101 attctccttt gttgatttat ttatttttat acaatctaca gaaacatgtt aaaatacttt
     5161 ttctatttca aatccaatca accttcactt acaattgcat ctgttccaca taatatattt
     5221 tcacattttt ctattgatat aattactgta tcaaaataaa agcactcttg ttttgataca
     5281 gtaattatat caataacaag agtgctcttt atttatttat cctaaagaat ttcctatttt
     5341 tttatactta aattcttaca aatttcatac aatcggaata ataaccttaa aggtaattat
     5401 attgttctcg ctatgagctg ttattgtccc gttatgaagc tccactattt ctttagctat
     5461 agcaagtccc aacccagctc taccactgtt tgaattacga gatgtatcca acctgtaaaa
     5521 ttgttcaaaa atacgctcaa gtttttcctc tggaatcgta ttgctatgat tcataaattt
     5581 aagctttata taatcatcct cctgtacagc tgttatttca atagtagtat cttcaaaact
     5641 ataataaaca gcatttcgta ataagttatc aaatacacgt tgcattttat taacatcaca
     5701 ccttatcatc atatttggtg taacattcag tgtatatttt aaattcttac tcatcaaagt
     5761 aggtttaaac tcatatgtta gttgttcaag catacgagtt aagcttactg tactgtattc
     5821 aagtgatata tttgataaat taaaccttgt aatttcaaag aattcattaa ttaaatcttc
     5881 aagacgctct gccttatcca acgaaataga taaatatttt tttcgcagtt cttcagaaat
     5941 ctgactttca tctcgaagta gtgtcagata ccctataact gatgtaagtg gtgtttttaa
     6001 atcatgtgca agataaacaa taagttcatt cttacgttgt tctgccattt gtgtctcaaa
     6061 tttacgttgt tcaagtatat gtttaattga gtttattttc ttttctattg ccaataactc
     6121 tggagataaa gccacttctc caacatcttc tttgataaga gagtcaatac cttgatttat
     6181 ttcactaaaa tattttgtaa accaatttaa ataaacacgg aatattataa aaaacacaat
     6241 caccatagct agtatcatga agagctccat gctattacgg aaaatctgct gatataaatt
     6301 caatgcagct ttatattcca tacgaaaagc attttcaaag aatgatacta tccagataga
     6361 aaacttacca tacaatataa aagaatataa aatccatatg aaaataatgg ctataaatgc
     6421 cattaaagct gttctcataa aaattttatt tctcacttga gtaaagtcag gattgacttt
     6481 aatattttta cttttcaatt gtataaccta ctccccatac agtttttata aatttcgggt
     6541 ttttagaagg ttcatgaatt ttttcacgta atcgccctat atgagccata actgtgttat
     6601 tattatcaag atatttttct ccccatacag cttcaaacaa ttcttcagaa ggaaccactt
     6661 ttccttgatg ttcacataaa taccaaagaa tagaaaattc aatcggtgtt aatgctactt
     6721 ctttcccaaa taaactacat ttatgtgttt ctttattgat aatcaatcct ttaatatcat
     6781 actcattaac aattatcgac tgttgttcat aagaattatt atatcgcata tatcttctta
     6841 attgtgtctt tactcttgca acaacttcca aagggttaaa tggctttgtt atataatcat
     6901 cagcacctat ggttaaaccc attatcttgt ctatatcttc aattttagct gttaacataa
     6961 tgataggata atagtatttt tctcgaattt tctggcaaat atgaaatcca tcaatatcag
     7021 gaagcataat atctaaaata gccatatcca aatctttaga ttcaatacat tctagagctt
     7081 ccttacctgt ataaaacttg tatactgtaa aaccttcatt ttttaaatat acttcaatta
     7141 aatctgctat ttctttttca tcatccacaa tcaaaatatt ttcgttcata gattattttt
     7201 cactctcctt attatcgagg tcatcattta taatattggt aaatttacat atcaaataat
     7261 tacaagcata tttgtaacta atttttataa gaaaagaact actacatcag aatgtgttga
     7321 tgctactatt ggaacacaaa aactgagatt aattgttatt ataaaaactc ccctaacacg
     7381 tccttattat cgcataacag gtattaactt tcaataaaaa tatctatcag tcaaacacaa
     7441 ttcaatttat tataccagag acaatccata taaaaaacaa ttaaacctat gtatgtaacc
     7501 acagacatta ctaaaatttc catgttattt tatataaaaa ttcaaaaaag gagttgaatt
     7561 taaaatttga ttagaaaaaa atcaattttg agacaactcc tttttatttt aatgtattta
     7621 aattatagta tatcagcctt cataatatcc tcaaaatcac ctttttcaga tattaatctt
     7681 atcaatttaa cagtacagct taaatcattt ataagtatag ctccaactaa tgaaccatct
     7741 ttcataaata attttttata tattctttga ccttcatctt ttgatgaaat ttctttatca
     7801 aaattttgta tattaccaat actaaatact tttacattca ttgcatctaa tgaaactgga
     7861 tatacttcac tttcaaatgt caaattatct ccacttgcat ttgcccctgc tatttttccc
     7921 atttctactg aagatggcca tattgctaaa ctaatatttc ccacttgtgc aacatctcca
     7981 caagcatata tatctttaat atttgtctgt aatgtcttat ctacaacaat acctctatca
     8041 atttttacag atgtatcctg aaccatttga gtgtttgctc ttacaccaat tgaaaatact
     8101 accatatcac agtcaacact atctccatct ttaaatacaa ctttttgagc ttttccatca
     8161 ccttcaatac catcaactgc tacacccaat cttacatcta ttcctgtatc tcttacacat
     8221 tgttctaata ttttactacc ttctttatca agttgttttg atagtatgct atccatggct
     8281 tcaactacta ctacttctaa tccttttagt ctaaattccc atgcagcttc aagtcccaat
     8341 aaaccgccac caatcactac aactttctta gatttttcta gtgcttcttt tacactatat
     8401 aaatctttta tatttctaag agtaaacaca ttttctaaat catgaccctt aattggtggt
     8461 ataaagtttc tacttcctgt agctattaca agcttatcaa atttaatagc tccatcattc
     8521 actataatag ttttattcac ttcatctaat ttatctacat tcgttcctaa tattactact
     8581 atattatttt tatcatacca atctttatct tccatgtaga aatctgaacc aagttcttca
     8641 tttataccat cagaaagtgc aggtctatag taagtcaact catcttcatt agaaatcata
     8701 gttatcttac aagttttatt tctttttctt atagcatctg ctgcataaaa accagctgct
     8761 ccatttccta ttattacgaa atattcatca gtatcttttc taaaagtaac ttcatcttct
     8821 tcaacttcta taaattggtc ttccttagct ccacatacag ggcatacact aggagcacta
     8881 tcactttcaa aaacttcatt acaaattaca catttaaatt tcttagtttt ctttttactt
     8941 ccaaaagtag aatttaactt atctaggaat ttacctgtat aagaatgtaa tttatcaatc
     9001 tcttcatttg atggtttaaa gttaacagca aaaggtttta ctgctgtcat tctaagctga
     9061 cttattctct ccatagcatt ttctatacct tctccactcc atccatatga accaaatact
     9121 gaagcaactt ttccaccatg aagaactggg tttaacgata ttaatatatc ccatataggc
     9181 tttaacgcat ctcctaatat tgttggtgtt ccaaataata caccttgtga tactgctatt
     9241 tttgccaaaa tatcttcttg cttatgctct attacatcaa ataaatttac tttatagttg
     9301 ctattttttt caatatatgc ttttatagct tctgccataa tctttgtata tccatgtgca
     9361 gaaacataac aaattgtaac ttctttttct aactttattt gttcatttac actccagttg
     9421 taataaaggt ctataatttt tctaggattt tcagttaata ctggaccatg acctggacat
     9481 acagtatcta tatctaaatc ttttatcttt tctatagcag ttaccataga tggtttaaat
     9541 ggacccatta tacaatcata atagtatctt aaagcatcca agtaatcctt ttcttcattt
     9601 tcatcaagtg tatttactat cttatcatta ctatagtgac taccaaatga atcacatgtt
     9661 acaagagttt tatcctcttt tatatatgtg tatatggtat ctggccaatg aagcataggt
     9721 acagagaaaa attctaaagt tttgtcccca attgataatg tatctccatc tgtaactgca
     9781 acatattcaa agtctttgtt tacgatttcc ttaagatatt taattgctgt ttctgaagct
     9841 actacttttg catttttagc taaatccaaa agcttttcaa cgcttcctgc atggtctggt
     9901 tcagtatgac ttacaacaat atagtctatt ttttcaaaat ctatatttaa atcatttaat
     9961 ctttcaatat aattgtcaaa atgcttatct ttaactgtct caaataaaac tgttttttct
    10021 gttcctttta atacatatga attataagta gttccataag gtgtatacat aattatgtca
    10081 aatactctta aatcagggtc aagcgaacct acccaatata aattttcttt tatttttagt
    10141 gatttcaatg acataccgta ctcctcctaa aatagttatt tagtctcttt ataccctgct
    10201 tgttatattt taaacaaaat ttattcaaaa aagaaattat tttaaagata gtttaaatct
    10261 tctaatcttc tttttctacc ttcaatacag ttcccttttt agaatctact tttatgtcat
    10321 attcattttt atctttatct attcttattt tataaaaagt aacatctaaa tctttgtcta
    10381 aactccattc tttaactatt ccattttgtt cttttaatgc aatttccata gcttgttgag
    10441 gtgtcattat gtcatttaaa tctaattttt cttttctagc aactccattt aaatcttctg
    10501 aatccaactt ttctgtttta tcttctaata catcttttgt attagcatca attttcatct
    10561 tatattcatt attatcatct acaccttcca cagtataaac aaatttattt aaatctctct
    10621 caagacttaa atctactata tcagcatcct tatatttatc tttaaatatg tttattgcat
    10681 ctgtgtatgg cactttaaaa tcttgttcca ttaaattttc attatttttt tcatctttta
    10741 aagcgttatt tgatgcattt gcctcctttt ttgtattatc ttgtgcttgt cctgaatcct
    10801 tagttggact cccactacat gcagttaata aacccgctat aagcatactt accactaata
    10861 aatacgtttt tttacacata aaaaccctcc ttaaatatat taatttattc tatattatgc
    10921 cctctaaacc ctttatttac ccttttatat taaaaattcc tcctatttta tcaattttaa
    10981 aactttatat ttactaaaat taaagttaca taaaaattat actgtctcaa aatggaaaca
    11041 agcctctttt tcattgttga aataataaaa atatatttta tttcgtacaa aaagagtgcc
    11101 tcatgaacta aaaagttcat tttgagacac tcccattttt ttatattttt acttacaaaa
    11161 taacagtact tattaatttt ttacaaacct tataagtata tctatatgat attcttaaat
    11221 ttaaacacta tattaaaaaa ttaaattttg tttaattctt ttaccgttaa atccatttta
    11281 ggatatggaa tcgtaattcc ttcttcgtca aacctaactt taacctcttc tagtaaatca
    11341 agataaattg tccaataatc ttctgtcttg caccaaactc tagttgcaaa tttaatagca
    11401 ttatctccat gttctactac tcctataaat ggttctggtt catttattat taatttatga
    11461 ttattaacaa tatctttaag tactcttcta acatgtagta tatcatcttc ataccctaca
    11521 ctaaaagtca aatcaactcg tctagtattc tttgctgaat agtttattag actatcattt
    11581 gatacagaac cattaggtat aagtatctgt ttattatctg gagtaaccaa ttgtgtataa
    11641 aaaagaccta tttgttcaac cgttcctcca tgacctgctg cttctacgta atctcctact
    11701 ttaaaaggtc taatcaatag tataataaat cctccagcaa aatttgatag actaccttgt
    11761 aaagccaaac ctattgctac ccctgctgat gctatcacag cagcaaaact ggacaaactc
    11821 attccccaat attccagaac aatgattata acggcaactt taagtacact caaaagaaga
    11881 gactttaaaa actttcttaa agttaaatca atatctcttt tactaagtaa taacataaca
    11941 tggtttacaa atttttttat tattttaaat ccaatagaaa gtataagtat gcctattata
    12001 agttttactc cgcttgtagt agcccattct agcagacttt ccattatacc tcccatatcc
    12061 atcttattaa tatctaaatt atttaaatct aacttgctta tatcatctat tttcgtcgta
    12121 tccataaaaa actccttacc ttatatttta gaaccaatat tatagtttaa agttcttatt
    12181 ttctatttaa tataatacaa taccatttgt acatagtaaa caagatttat attccaatta
    12241 tacatattag gaaaatgcaa actatttgtt atatatatgc aaaatataat actaaattaa
    12301 actattaata aaacactata tagccttaaa atcatcattt tttaccccta tatgagatga
    12361 tactatagtt ataatactta atactataaa tactacaaaa ccttttttat atccatcaac
    12421 tatattatat gaatttactt gtaaagagat agctataatc aaattaataa ttccacttcc
    12481 tataaattca aaagtattaa taacactagt tgccagtcca gaataaattt ctttattttt
    12541 atacttggca tcattaaaaa cctgtagatg tgacataact atacatccca taataaagaa
    12601 tgatattggt aaaactataa ttggtggttt tacctggtat acaactacaa ttacaatcca
    12661 tataaacaaa tctatcattg ctccaaattt tattatatta aatttgctag accttatttt
    12721 agcaaataca aaatccataa ttattgaacc aaatataaat ccatatgtaa aaaatgatac
    12781 tataaacgca gaaaaactct tactcacacc ataaacgtcc attatgtatc ttactcccca
    12841 taagcttata aatgcacttg taagaccaac aaaagagaac attatcattg aattatacca
    12901 tgttgatttg ttctttataa cagacttaat accatcaaca atattaacct tctctgactt
    12961 ttcatagggt tcagtatcta cattgaatcc atactctttt ggtgtatctc taacaataat
    13021 atacataaaa catccaatta caacaccaat tataccgatt aataaaaatg aatttctcca
    13081 accaacaagt tcagacaaaa acacaagtgg aaaagtagca agaactccac ctaaatttcc
    13141 tacaaatgaa aatttagctg ttgcagaagc aaattctgac ttattaaacc atctcccttg
    13201 aatttttaaa atacaaagta atattactga tgttcctgcc cctacaatta cacgagaaat
    13261 atatgctaat tctatacttt gaatcaaacc aaataaaatt gaccctaaac ttgccattat
    13321 tattccaaga ctgctaattt ttcttgctcc atatttatca atcaaaattc ctgcaggtat
    13381 ttgcataaat gcatatgcat ataggcaaaa ggatgctata tttgaaattt gtatagaatt
    13441 aaaacctaac tcatttgcta aattgtctga aacaacagca gttgacatcc ttaaaaataa
    13501 tactaaaaca aatgaaaatg taattatacc ccaaacactc cacttagcct ttgtataact
    13561 tttcatatct tctccctcaa atccatatat ttttaaattt tcttgatata acttatataa
    13621 agtgtatagt tattcttaca aatttttaca cgcaatatca ttatacaaca tatgtatata
    13681 tttaactaga aataaaacac tattcatatt atatacatga attaactaca taaataataa
    13741 gagctatctt ttaacattac tcaaaagata gctccatata aaaacattta ttctaaattt
    13801 aattttttat ctaatataaa ttttgtagcg aaaaataacg ctattgcaac tacaagacta
    13861 ccaagtattg caagcataaa actaggactc tgataaagat gatataccat atttgtatct
    13921 tcatttggta agatgcttcc aactgcatct ccaacaattg atattactat atttatagct
    13981 ataaaagaag caaatgccac tatgtttcta tgtttattga attttggcaa ttgtcccatt
    14041 gagattgatg tatataataa caaaataaat gatgaatacg aaataaacat tactactact
    14101 aataataaaa tatctaaaaa gttttcagaa atccatttaa aactagtgtt aaacaaatct
    14161 aaaatttcag gtagtaaaat tccagaagta ccaaaaagca taagaactcc aaaagtgaat
    14221 actgcaacta taaaactaag tacagcgtat ataagtgctg ttatacattt agataatata
    14281 agtgaactag tgctaacagg aagagtaaac attaaataac cttcatcccc caaaagattt
    14341 tttctaaacc tttgaattgt aactacaata gttaaaactc ctaatgccat aaaaagactt
    14401 gttaatacta gtattcctat tccctgtacc tgaagtatat ttgtattcat aaatattcca
    14461 ttaaatacag ctactatcaa tatggctata tataacggta taaatattct tccacttgct
    14521 tttaactcat attttaataa tttacctaac atttaaattc ctccctaaat aatgcatcta
    14581 tagattttcc tttttcttct cttattgctt caacgtctcc ttgtaacact atttctcctt
    14641 ttgatatgaa tattatctca tcacatatgt tttctatttc acttattaag tgggtagcaa
    14701 tcagtaaagt actatcttca gaataatttt ttaatatagt cttaagtata tatgaccttg
    14761 cagctgggtc aacaccacct ataggttcat ccaatatata tatgctcgca tttcttgaca
    14821 ttactaaaat aagttgaact ttttctttag ttcctttaga cattgtcttt agcttttcat
    14881 ttacatcaat atctaagctt ttaatcatct catttgctct tctaacatca aaatcactat
    14941 aaaaatcata gaaaaactta agtaaatctg ataccttcat ccaatcattt aaataagttc
    15001 tttctggtaa atatgaaact atttttttag tatctatgga tggtttcatt ccatttatca
    15061 taatttcacc attatcaggc tgtaataatc cattcattag cttaatcatt gtacttttgc
    15121 cacttccatt aggtcctaac agcccgacta tttttccctt tggtatattt aaatcaatat
    15181 tttttaaaac attcttagtt ccataactct tgtttacacc tttaaattca actattccat
    15241 cttgagaaac attgcttata tttttatcca ttttataatt ctcctttcag attttctgta
    15301 ataagtttta gcatttcatc tctatcatat ccaagctttt ctaaggttac ttttaatgta
    15361 tttatctcca cattagctat ttcctctttc atagctttta ttttttcctt atcatctgtt
    15421 acaaatcttc ctttagttct ctgactataa actaaacctt gtctttcaag ttctgttaga
    15481 gccttttgca ttgtatttgg attaacttcc gcatcttctg ctagtgctct cactgtttct
    15541 aatttagatc ctattttaat ttcccctgaa attattttta actttaaatg ttctactaat
    15601 tgtatatata taggtttgtt attatcaagt tcccattcca tgttcatgcc tccttattat
    15661 attattgtat taagttgtta atacaataat ataataatac aaagtatatg tcaattactt
    15721 tttagtaaaa gtataaaaaa ttttacaaaa aaaatgaaca ctacattaga gtccattttt
    15781 aacacaattt attaaattct ttatattaca gattaattac cctcttacca agttagatac
    15841 aattaaatgt tcaaattctt caattggcat tggctttcca aacaaatatc cttgtgccat
    15901 atcacacttt acttctttta aaagtttaaa ctgttcttct gtctcaactc cttctgatat
    15961 gactttcata cccaactctt ttgccatttc tattacttta gtaacaatta ttttgcttct
    16021 tttactatta taagtttcca taataaattt ttggtcaagt tttaagatat ccataggaat
    16081 ttcttttaac atatttaatg atgagtaccc tgagccaaaa tcatccatag atattaaaaa
    16141 tcctattttt tttaaattat tcattatatc aattaaaata tcaaaattat caaatatgat
    16201 actctccgtt aattcaagtt ctatatactt tgcaggtata ttgtatttat caattatatt
    16261 tttgtatgtt tctataaaat tattgcaata taaatgtatc cttgaaacat taactgaaac
    16321 agtaactgga tttattcctg catcaatcca ttttctaagg tatatacata cttcttcaag
    16381 cacatataaa tctaaattta taacaaaacc gtttctttca aaaaatggga taaattcatt
    16441 tggaggtatt agccctttat caggacgttt ccacctaaca agtgcttctg aaccttgtat
    16501 ctctcctgta ttaagttcta tcttaggttg taagtatata ataaattctt tattttctag
    16561 acttgaaaac attgtatttt ccatctcttt ttcttttatc tcttggtcat gaatcttatt
    16621 atcataaaat gcatatgaac ttttatgtcc tccctttgcc attttatgag gtatattagc
    16681 cctatctatg attgagttga tatctctatc ttctggaagt ataaaataga ttccacaact
    16741 taaaactaac ttatattttt cttcttgatt attattaaac aagtctaatt cttcaaatat
    16801 agtttttaac ctctttgtta tatcttcttc ttctatatat ttcataatta taataaaatt
    16861 atccgcagat attcttgcaa acatttcctc ttcaaatata ttcctcttaa taatctttgt
    16921 taaattacgc aaaatttcat tcccaacttc atatccaaat aaatcattta tatatttaaa
    16981 tttatcaata tctatatata ataaagcata ctttacttga gtatttttac atagtatttt
    17041 gttagcatca attacaaatt tatctatagt atttgctcct gtaagattat ctgtatatgc
    17101 tatcctttgc aatttaattt taaaatttaa tttatcatat attatataga atataagtat
    17161 tacacatatt atagccataa taagtattat ttgtattgca tgtttgctaa taagctgatt
    17221 attagacaca atagactcaa agttatttat ggagttgttt ttatagagtt tgcataaaga
    17281 atagactggt gttgtgtatg taatttgtaa aattatacaa ataaataaaa aaaacatcaa
    17341 ttttttttgt aaattcctca taaaaatttc ctcccattaa aacacctcta ttttattagc
    17401 aaataagtac atctcaaaag ttt
//
LOCUS       DAMKNB010000073        17196 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.077, whole genome shotgun sequence.
ACCESSION   DAMKNB010000073 DAMKNB010000000
VERSION     DAMKNB010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 17196)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17196)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17196
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.077"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            complement(130..654)
                     /locus_tag="PC494_002767"
     CDS             complement(130..654)
                     /locus_tag="PC494_002767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HDF3913258.1"
                     /translation="MENKNPIVTIEMENGKEIKIELYPNIAPNTVKNFVSLVNEGYYN
                     GIIFHRVIPGFMIQGGCPNGTGMGGPGHSIKGEFSGNGFTNNLKHERGVISMARTMAP
                     NSAGSQFFIMHKNSPHLDGQYAGFGRVIEGMDTVDEIASVRTDSADKPQTPQVMKSVT
                     VETFGIDYSDVEKN"
     gene            complement(719..1471)
                     /locus_tag="PC494_002768"
     CDS             complement(719..1471)
                     /locus_tag="PC494_002768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
                     /protein_id="HDF3913259.1"
                     /translation="MKLGLCLEGGGAKGAYQAGVVKALYDGGINKFYSISGTSIGAIN
                     GYYLYTGNVDNLEKMWTNIKDIQNGNVKIVNNTVDNSPAIDNLRELDDSNIEEMNFYV
                     NYVEVDNKVVSEKIVDVSKMPRNEAIISISYSGLLPSNPNATLGFKEQFVKDVQEGIY
                     DGFKLDGGLIRSALIEPLIGDNVDKIILISTKYNYELPEDIKKVYDEDKIIVVRPNTQ
                     FAPKDTLNFDDEFCKTIYQEGYEIGKNILDRL"
     gene            complement(1502..2800)
                     /locus_tag="PC494_002769"
     CDS             complement(1502..2800)
                     /locus_tag="PC494_002769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M18 family aminopeptidase"
                     /protein_id="HDF3913260.1"
                     /translation="MDSINFAKNLIDFIYDSPSSFHAVESTKEILDKNGFEELVLNQR
                     WNLRVGGKYYVTKNLSAIVAFVVNSEGIERDGFRIIGSHSDSPTFSIKPNAEIEAEKS
                     YLKLNTECYGGAILSTWLDRPLGIAGRVVLKGDSILKPNERLIDFKKPICIIPNLAIH
                     LNRSINDGHSYNKQKDMLPLVGMLNDTLEKDNFLIKQIASNLDVNMEDIIDFDLFLYE
                     FEKGSLIGANDEFISIGRQDNLAMVHASLNALVNTKGQHGVNVMAVFDNEEVGSSTKQ
                     GADSNMLLNILERICISMGKDREGFFESIYSSFMISSDLAHAIHPNIPEKHDPTNKPI
                     MGKGPVIKINASQAYTSDGYSIAIYKNICREANVEYQEFVNRSDERGGSTIGPISSTH
                     IDIPSVDVGSPILAMHSIRELGNVEDHYSIYKTFSKFFEI"
     gene            complement(2817..5081)
                     /locus_tag="PC494_002770"
     CDS             complement(2817..5081)
                     /locus_tag="PC494_002770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3553 domain-containing protein"
                     /protein_id="HDF3913261.1"
                     /translation="MNLDTLNPAQREAVEKTEGPVLILAGAGSGKTKVLTTRIAYLIE
                     DKGVQAPNILAITFTNKAANEMRERVEQNIGPETKDMWISTFHSCCVRILRKDINKIG
                     YNRSFVIYDSADQVTLVKDCLKELNLSDKVFEPKAVISAISGAKDKLYTPKQFKDINM
                     ADNRMVKIADIYALYQDRLKRNSALDFDDLILKTVELFKANDEVLAYYRSRFRYIMVD
                     EYQDTSKAQYELIKLLAREHQNICVVGDDDQSIYGWRGADIRNILEFEKDYDNVHVVK
                     LEQNYRSTQVILDAANKVISNNIERKRKKLWSEKKEGELIKIQLTGSEIEEADFIADS
                     IAQIARKENRPYKDFAVLYRANAQARPVEDALNRSQIPYNIYGGTKFYERKEIKDLLA
                     YLRVIQNPQDDISIKRIINVPRRGIGLRTIEKIEDRANLKQESIYSVLIDIETNSDIS
                     TKARASISGFVDIIGTLRTIKEVYPVSKLIEKVLDTTGYMDELVEIRNKNEKDLTGKG
                     EEAQDRIDNLREFISIALEFESSNDDTYENKDLETFLTSIALTSESNDEEDNDRVSLM
                     TIHTSKGLEFPVVFLTGMEEGLFPISRAIKSMSDSQIEEERRLCYVGITRAKEELYMS
                     LTEKRTLYGKTNVAIASRFMEELPEECIERLYKVKKELSYSKASYNMLDKYTKKYMST
                     ISKSKVADKVNATIKDSNKETNPDDIKLGSKVHHPKFGVGTVVSIIGTDVTIAFDQQG
                     IKKINKEYTTLNIL"
     gene            complement(5336..6154)
                     /locus_tag="PC494_002771"
     CDS             complement(5336..6154)
                     /locus_tag="PC494_002771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HDF3913262.1"
                     /translation="MFKINNLTYQYEKNTNALLNINMDFSKGNVIGIIGSNGSGKSTL
                     FMNLMGILKPTSGEILFKEEKLKYDKRSLYNLRKNVGIVFQDPEKQIFYSKVYDDIAF
                     AMRNIGMDEKTIKERINKALVAVNGIDFIDRPVHFLSYGQKKRVAIASVIAMENEIVL
                     LDEPTAGLDPVSTRSIVDIIKGLNKNNIKIVISSHDMNLMYEICDYIYVLDKGILIDE
                     GKAENVFINENNIIQAGLESPWLVKVHRNMNLPLFKKEEDLYKYWKERELNTNK"
     gene            complement(6147..6845)
                     /gene="cbiQ"
                     /locus_tag="PC494_002772"
     CDS             complement(6147..6845)
                     /gene="cbiQ"
                     /locus_tag="PC494_002772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt ECF transporter T component CbiQ"
                     /protein_id="HDF3913263.1"
                     /translation="MLIIDKYAYTNRLSKVNPNKKVAIGVIFLIASMVIQNIFILSGI
                     MILMSILVVCVAGIDLKNYLKLLRIPMYFLFLSIGITLVNISFNKADLLYSFEFFSFN
                     VGISKASIDMSIHVLFRAMSCLTCVYFCILTTPFNQLIFFFKKLHLPDTFVELSMLIY
                     RFIFIFLEEFSEIYKSQELRFGYINLKTSYKSLGILGSMLYKRLMTRYDDMCISLDIK
                     LYDGKFHIVGDNDV"
     gene            complement(6848..7126)
                     /locus_tag="PC494_002773"
     CDS             complement(6848..7126)
                     /locus_tag="PC494_002773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     substrate-binding protein"
                     /protein_id="HDF3913264.1"
                     /translation="MSAKTKTNILLLLLVVALIIFPLLVNSGAEYGGADGQAESEITK
                     INPNYKPWFSSPYEPPSGEIESLLFSAQAALGAGVIGYILGLQKGKRS"
     gene            complement(7116..7868)
                     /locus_tag="PC494_002774"
     CDS             complement(7116..7868)
                     /locus_tag="PC494_002774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006440549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter permease"
                     /protein_id="HDF3913265.1"
                     /translation="MKQNIKLGVIAALMLIILTPVTSNAMHIMEGYLPVKWSIAWGVI
                     FIPFFLFGLKSIGKIVKQDPKKKVLLALCGAFVFVLSALKIPSVTGSCSHPTGVGLGA
                     IMFGPSVMFVLGTIVLIFQALLLAHGGITTLGANAFSMAIIGPIVSFLIFKALKKKDG
                     NNAIPVFLAAAIGDLATYTITSIQLALAFPDPSGGVMASAIKFLGIFFMTQIPIAIAE
                     GILTVIVYNLITENGEKSILENNDKGVKANEC"
     regulatory      complement(8050..8242)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00174"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cobalamin riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="adenosylcobalamin"
                     /db_xref="RFAM:RF00174"
     gene            complement(8374..10146)
                     /locus_tag="PC494_002775"
     CDS             complement(8374..10146)
                     /locus_tag="PC494_002775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitric oxide reductase activation-like protein"
                     /protein_id="HDF3913266.1"
                     /translation="MKWIYDDYEFENRANNLSWTIAGDYNESIDISEKDYSSKEIGLY
                     FAIIAGARRKYVDWDIVKKYLTNRIRKGYNKDIILGLIQVILNTIVEEKVIKDRPGIE
                     DIRRNAYKDIVSRFTKIHNDNIMDKIKYTFVLYSMDKHPALDSMTRRIVNDIRNIDTN
                     QDIMEILKALDVIYLTYFEYILNGEENSLIDENNVESVEVNFDTFADFMYEELYSDEE
                     ENIIESDIDSISSSMLVEGVGDFDDSKCSNSADRVIYVDEDTANKIYSKIEHYYGKTY
                     LSKGEIKKIETQNCRNVHEGCRIHFTDGVLRSECNNVFQLKYVTRQKENNLGKFREHA
                     RMYRQQIKRLKESLSRILIEENAKSRVYSDCGTILANRAWRVGRSNNNKIFYKDIENE
                     KGKYVIDILLDASGSQSRNQGNVAIQAYIIANALTEVGIPNRVMGFSSFLDYTILKRF
                     KDYDDSIKNSENIFEYFCAGNNRDGLAIKSICSGLINRDEENKILIVLSDGRPNDVKI
                     GKSSERTLRGEKAYRGIVGLRDTANEVRKARKQNILVLGVFTGKESELEAERLIYGND
                     FIYSRDITRFSDVVSMYLKKIIRN"
     gene            complement(10160..11089)
                     /locus_tag="PC494_002776"
     CDS             complement(10160..11089)
                     /locus_tag="PC494_002776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HDF3913267.1"
                     /translation="MDIIDNLRVQGVDEKLIEDVLYFRNYYGLEKDLEYRVTKSKTYF
                     YGKDILSMCIAAILEEENILLSGPKATGKNLLADNLGEIFNRPQWNTSFHINTDSSTL
                     IGTDTFIDNEVKLRRGSVYECAINGGFGVFDEINMAKNDAIVVVHSALDYRRIIDVPG
                     YERVNLHPATRFIGTMNYEYAGTKELNEALVSRFMVIDIPPIEEDKLMMILKNEFSDA
                     DEEKLIHFAGIFLDLQLKSQNGEISSKAIDLRGLMASLKTIRRGLKPTLAINMGLTGK
                     TFDVYEKEMVGDVIKTRIPNKWESIDVFPISHI"
     gene            11317..11505
                     /locus_tag="PC494_002777"
     CDS             11317..11505
                     /locus_tag="PC494_002777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF3913268.1"
                     /translation="MEYMSCPEVAKKWGISERRVQKLCEESRIPGVSKLGYMWLIPKN
                     AEKPVDGRTKRRKEVQYE"
     gene            11498..12199
                     /locus_tag="PC494_002778"
     CDS             11498..12199
                     /locus_tag="PC494_002778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF3913269.1"
                     /translation="MNSVLIIDDDKELCALMKKCVEQENLSAIIAHCGAEGLHLVDKN
                     RHTLSLVILDIMMPDIDGFQVLKKIRETSNIPVIMLTAKNDEDDKVSGLRLGADDYLT
                     KPFSINELMARVNSLIRRYTMLNPAFITDTDCIIINGMIIDKTNRIVSVNNIPVQLTS
                     KEFDLLAFLASNKGQVFTKKQIYTQVWEEEYAFDDSNIMSFISKLRKKIEPDPNHPFY
                     ILTVRGVGYRFNKEA"
     gene            12201..13124
                     /locus_tag="PC494_002779"
     CDS             12201..13124
                     /locus_tag="PC494_002779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF3913270.1"
                     /translation="MNTSVYLLLILVLSLIIIAYLVSVLLRVRIQLTLIKDALEDIKN
                     GNLNRRILTDENDITKQICYDINEIAINSQFQLIQQKQSEQAYKQLMTSLSHDVKTPL
                     ASLVGYLEAVESKIVVGEEKDEYIHVASNKAHYLKNFVENLFEWVKLDSKEQVFHFDI
                     FDLNELSRNIISDWIPVLESSHFEYEFDIPEIEYFLRIDANAYTRIINNLLQNIITHS
                     SGNKMTLRIFENKEQAQIIITDNGKGISSDNLPHIFERLYQCDHSRASKGNGLGLAIA
                     KELINAHKGNITANSTPGMGTEFTILLPKAL"
     gene            13281..14204
                     /locus_tag="PC494_002780"
     CDS             13281..14204
                     /locus_tag="PC494_002780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019639192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF3913271.1"
                     /translation="MNDFVIETKQLTKIYGNQTVVDKVNLHVKKGRIYGLLGRNGAGK
                     TTIMKMILGLTSITYGEVDVFGENIKEREKQVYPRIGAIIETPGFYPNLTGTENLEIF
                     AKLRGTAAPNSVKRALEIVGLPYKNKKLFSKYSLGMKQRLGIANAILHDPELLVLDEP
                     TNGLDPIGIAEMRKFIRDLSVEHGKTILISSHILSEISLLADDIGIIDHGVLLEESSM
                     SELEKKNSKYILLQVSDIPKTSLILERQFNTKDYSVQDDYTLHLYNTNLDMGEINKAL
                     VMQNVTVISSQLCNDTLEDYFKKITGGEGIA"
     gene            14197..14934
                     /locus_tag="PC494_002781"
     CDS             14197..14934
                     /locus_tag="PC494_002781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF3913272.1"
                     /translation="MLKLIQTEFLKLRRRKLIWLMLLSALIMPFFALLYFNYFGKTGV
                     EPIKFYKWSAFGYTLWIILPVVLGIFCTMLIHEENQYDMLKQLWIVPISKMGYFFSKF
                     FVVLIYSICFMLITAVASVLFSVLSGYVVFSWASILYLLKKCLEIGVITAFVMLPILA
                     IATSQKGYILPICITLVYAFSGFVIMTINMYLHPLSSMGVIIMRNKDIPGLIFSQEIN
                     VPLAFLCICIWSIVSVLFANIALGRRK"
     gene            14945..15718
                     /locus_tag="PC494_002782"
     CDS             14945..15718
                     /locus_tag="PC494_002782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF3913273.1"
                     /translation="MWKLLWAECQKIRRSKIVWITVFASIMIAVIVFAGGQDVYNDPD
                     LHYGLKSVYDGSRYIDNAGWYMDAVQPWSTFFVLPAVIALLGSYIICREEEEDTIKSL
                     RLIPINETNLTIAKMIITFIFSILLYLLLFTITFLTESVLHFSDLSTKLVLSCMKEYF
                     LDGIGVFFAISPIIALVSRMKKGYWLALVFTEVYSIAGLFAGMSNVLQTFFPIAAIFN
                     ISGYYITTGEKIMGSIISLLLCACLSAFILKGLKHNEKN"
     gene            complement(16245..16853)
                     /locus_tag="PC494_002783"
     CDS             complement(16245..16853)
                     /locus_tag="PC494_002783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DedA family protein"
                     /protein_id="HDF3913274.1"
                     /translation="MSVINSFILQYGLISVFVLIMIEYACFPLPSEVVLPLCGAIAAR
                     NHFGFLTILILSIIAGILGSIFCYTVGNWGGKSIINKIIEICPKAKKGIFASQDYFNK
                     YSSISVCVCRLIPLCRTYISFIAGIAGQNIITFVISSIVGITIWNTSLISIGYIFSES
                     WVRIMSHYNDYKFLVLIIPISIIFIGFVIKSFIHKKHHKIRL"
     gene            complement(17031..17147)
                     /gene="rrf"
                     /locus_tag="PC494_002784"
     rRNA            complement(17031..17147)
                     /gene="rrf"
                     /locus_tag="PC494_002784"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
BASE COUNT         5535 a         2987 c         2172 g         6502 t
ORIGIN      
        1 caatacaaat aaattaaaaa gtgaaatgta tttgtctaaa aacataataa catttcactt
       61 tatcctcatt tttaagtaat atatattttt aatttttatt tataactaaa tctagttttt
      121 atataaattt tagttttttt ctacatctga gtaatctatt ccaaaagttt ctacagtaac
      181 agatttcata acttgtggag tttgtggctt atcagctgaa tctgttctaa ctgatgctat
      241 ttcatcaact gtatccatac cttctatcac tctaccaaaa cctgcatact gaccatctaa
      301 gtgtggtgag tttttatgca ttatgaaaaa ttgagaacca gctgaattag gtgccatagt
      361 tctagccatt gatatgactc ctctttcatg ttttaaattg ttagtaaatc cattaccact
      421 aaattcacct tttattgagt gacctggacc acccattcct gtaccatttg ggcatcctcc
      481 ttgtatcata aatcctggta ttactctatg aaatattatt ccattgtaat atccttcatt
      541 tactaatgat acaaagtttt taactgtatt tggagctata tttggatata actcaatttt
      601 gatttctttt ccattttcca tttctatagt tactatagga tttttatttt ccataattta
      661 ttaccttcct tttcattagt taaattacat aattacattt attatattat actctaaatt
      721 aaagtctatc aagtatattt tttcctattt catatccttc ttgataaata gttttacaaa
      781 actcatcatc aaagttaagc gtgtctttag gagcaaattg agtattaggt ctaactacta
      841 ttattttatc ttcatcatat acttttttaa tatcttctgg caactcataa ttatattttg
      901 tggatattaa aataatttta tccacattat ccccaattaa tggttcaatt aatgcactcc
      961 taattaaacc tccatctaat ttgaaaccat cataaattcc ttcttgcaca tctttcacaa
     1021 attgttcttt aaatccaaga gttgcgtttg gatttgatgg taacaaccca ctgtatgaaa
     1081 tgctgataat ggcttcatta cgaggcattt ttgatacgtc aacaatcttt tctgatacta
     1141 ctttattatc aacttcaaca taattaacat aaaagttcat ttcttctata ttactatcat
     1201 ctagttccct taggttgtct atagcaggag aattatccac agtattattt actattttta
     1261 catttccatt ctggatatct tttatatttg tccacatttt ctccaagtta tcaacattcc
     1321 ctgtgtacaa ataatatcca tttattgctc ctattgatgt ccctgaaatc gaataaaatt
     1381 tatttattcc tccatcatac aaggctttaa ctactcctgc ttgataagcc ccttttgctc
     1441 ctccaccttc taaacataat cctaatttca tagtctcatc tccaaattgt ttatcttata
     1501 tttatatttc aaaaaactta ctaaatgttt tatatatact atagtggtcc tcaacatttc
     1561 ctaattctct tatagaatgc attgctaaaa ttggacttcc cacatccaca gatggtatat
     1621 ctatatgagt agaagatatt ggacctatag tacttcctcc tctttcatct gacctattaa
     1681 caaattcttg atactcaaca ttagcttctc tacatatatt tttataaata gctatagaat
     1741 atccatcact agtatatgcc tgactagcat ttatctttat aaccggacct tttcccatta
     1801 ttggtttatt agttgggtca tgcttttctg gaatgtttgg atgaatagca tgagctaaat
     1861 ctgatgatat cataaaagat gaataaatag actcaaagaa tccctctcta tccttaccca
     1921 ttgatatgca aattctctcc aatatattta acaacatgtt tgaatctgca ccttgtttag
     1981 tagagctacc aacttcttca ttgtcaaata cagccattac atttacacca tgttgacctt
     2041 tagtattaac aagagcattc aaactagcat gtaccattgc aagattatct tgtctcccaa
     2101 tagatataaa ttcatcatta gcccctatta aacttccttt ttcaaattca tataaaaata
     2161 aatcaaaatc tataatatct tccatattta catctaagtt agatgctatt tgctttataa
     2221 gaaaattatc tttttctaat gtatcattta acatcccaac taaaggtaac atatcttttt
     2281 gcttattata tgaatgacca tcatttatac ttctatttag atgtattgct agatttggta
     2341 ttatacaaat tggcttttta aagtctataa gcctttcatt tggttttaat atactatcac
     2401 cttttaaaac tactctacca gctatcccaa gaggtctatc caaccatgta cttaatattg
     2461 ctcctccata gcattctgta tttaacttca aataagattt ttcagcttct atttctgcat
     2521 ttggtttaat actaaatgta ggagaatctg aatgagagcc tattattcta aatccatctc
     2581 tttctatacc ttctgaattt actacaaaag ctactatagc tgataaattc ttagtaacat
     2641 aatactttcc accaactctt agattccatc tttgattcaa aactaattct tcaaatccat
     2701 ttttatctaa gatttcctta gtactctcga ctgcatgaaa agacgacgga ctatcatata
     2761 taaagtctat taagttttta gcaaagttta tactatccat tcctcattta cctccattat
     2821 aaaatattta gtgttgtata ttctttattt atttttttaa ttccctgttg gtcaaaagct
     2881 atagtaacat ctgtaccaat tatagaaacc actgtcccaa ccccaaattt aggatgatgt
     2941 accttagaac caagttttat atcatctgga ttagtttctt tattagaatc ttttattgta
     3001 gcattaactt tatctgcaac tttagatttg cttatagtac tcatatactt tttagtatat
     3061 ttatctaaca tattataact tgctttagaa tagcttagtt ctttttttac tttgtacaat
     3121 ctttctatac attcttctgg cagttcttcc ataaatcttg aagctatcgc aacatttgtt
     3181 ttaccatata atgttctctt ctctgtcaat gacatatata gctcttcttt agctctagtt
     3241 ataccaacat aacaaagtct tctctcttct tctatttgtg aatcactcat agattttata
     3301 gctcttgata taggaaataa cccttcttcc atacctgtta aaaacacaac agggaactct
     3361 aaacctttgg atgtatgaat tgtcataagc gaaaccctat cattgtcttc ttcatcattt
     3421 gattcagatg taagtgctat acttgttagg aatgtctcta agtctttatt ttcataagta
     3481 tcatcattac tactttcaaa ctccaaagct atagaaataa attctctcaa attatcaatt
     3541 ctgtcttgag cttcttcacc tttgcctgtt aaatcttttt catttttatt tcttatctct
     3601 acaagctcgt ccatatatcc tgtagtatcc aagacttttt ctataagttt gctaacagga
     3661 taaacttctt ttatagttct aagagtccct ataatatcaa caaatccact tatacttgcc
     3721 cttgccttag tagatatatc tgaatttgtt tctatatcaa ttaatactga gtatatactt
     3781 tcctgtttta agttagctct atcttcaatt ttttctatag ttctaagccc tatacctctt
     3841 ctaggaacat ttataatcct ttttatagat atatcatctt gtggattttg aataactctt
     3901 aaatacgcca acaaatcctt tatttctttt ctctcataga attttgtacc accatatata
     3961 ttgtatggaa tttgacttct atttaaagcg tcctctacag gtcttgcctg tgcatttgct
     4021 ctataaagta ctgcaaaatc cttataaggt ctattttctt ttctagctat ttgtgcaatt
     4081 gaatcagcaa tgaaatcagc ctcttctatt tcgctaccag ttaattgtat ctttataagt
     4141 tctccttctt ttttttcact ccaaagcttt tttctttttc tttctatatt attagatata
     4201 actttattag ctgcatctaa tatcacttgt gtagacctat aattttgttc taactttaca
     4261 acatgtacat tgtcataatc tttctcaaat tcaagtatgt ttcttatatc tgcacctctc
     4321 catccataaa tactttggtc atcatctcca acaacacaaa tattttgatg ttctcttgct
     4381 aataatttta tcaattcata ttgagcttta cttgtatctt gatactcatc taccattatg
     4441 tatctaaatc tacttctgta atatgctaat acttcatcat tagccttgaa aagttctaca
     4501 gttttaagta ttaaatcatc aaagtcaagt gcactatttc tttttaaacg gtcttgatat
     4561 agcgcataaa tatctgcaat cttaaccatt ctattatctg ccatattgat atctttaaac
     4621 tgctttggag tataaagttt gtcttttgct cctgaaattg cacttataac tgcttttggt
     4681 tcaaacactt tatcacttaa atttaattct tttagacagt ctttaaccaa tgtaacttgg
     4741 tctgctgaat cataaattac aaaacttcta ttgtaaccaa tcttatttat atcttttctt
     4801 agtatacgaa cacagcaaga atggaatgta cttatccaca tatccttagt ttcaggacct
     4861 atattttgtt caactctctc tctcatttca tttgcagctt tgtttgtaaa tgttatagct
     4921 aatatatttg gtgcttgtac acctttatct tctataagat atgctattct tgttgttaat
     4981 accttagttt tacctgaacc agcaccagcc agtataagta ctggaccttc agtcttttct
     5041 actgcttctc tttgagcagg atttaatgta tctaaattca tatttctcct cctgttaaca
     5101 gccataaata tattttaatc taaaatatga attacttcaa attataatta tgtattatat
     5161 taatagatta tttccaatat attacaatta aataacattt ttccatataa tttatttcat
     5221 tgtttaataa aaaaaataac cttatgattt ggggaatcat aaggcacctt taaggggtct
     5281 aggttaaggg ttattatata taaatctatt tttttaaaat aggtttaggg cttaattatt
     5341 tatttgtatt aagttctctt tccttccaat acttatacaa atcttcttct ttcttaaata
     5401 agggtaaatt catatttcta tgtactttta ctaaccatgg ggattctagg ccagcttgta
     5461 taatattatt ttcatttata aacacatttt ctgcttttcc ttcatcaatc aaaatcccct
     5521 tatccaatac atatatgtaa tcacatattt catacattaa attcatatca tgactggata
     5581 ttactatttt tatattattt ttatttaatc cctttattat atctacaata gacctagtac
     5641 ttactgggtc taaaccagct gtaggttcat caagtaatac aatttcattt tccattgcta
     5701 taactgatgc tattgccact ctttttttct gtccatagct aagaaaatgt actggcctgt
     5761 ctataaaatc tattccatta acagctacta gagctttgtt tattctctct ttaattgttt
     5821 tttcatccat accaatgttt ctcattgcaa aggctatatc atcatatact tttgaataaa
     5881 aaatttgttt ttctgggtct tggaagacaa tacctacatt ttttctaagg ttgtataaac
     5941 ttctcttatc atattttaac ttttcttctt taaaaagaat ttctccagat gtaggcttta
     6001 atatacccat taaattcata aataatgttg attttcctga accatttgaa cctattatac
     6061 ctataacatt tccctttgaa aaatccatat taatgtttaa tagtgcattg gtattttttt
     6121 catattgata cgttaaatta tttattttaa acatcattat cccctactat gtgaaattta
     6181 ccatcataca attttatgtc taatgatata cacatatcat cataccttgt cataagtctt
     6241 ttgtacagca tacttccaag aatacctaag gatttatatg aagtttttaa atttatatat
     6301 ccaaatctta gctcttgtga cttgtatatt tctgaaaatt cttctaaaaa tatgaatata
     6361 aacctatata ttaacattga taactcgaca aaagtgtcag gtaaatgaag ttttttaaaa
     6421 aagaatatta attgattaaa aggtgttgta agtatacaaa aatacacaca agtcaaacaa
     6481 gacatcgctc taaataacac atgaatagac atgtcaatag acgcctttga tattcctaca
     6541 ttaaaactaa aaaattcaaa actatataat aaatctgctt tattaaaaga tatatttaca
     6601 agagttattc ctatactaag aaataaaaag tacattggta ttctaagtaa ttttaaataa
     6661 ttttttaaat ctattccagc cacacaaaca accaaaatac tcattaaaat cataattcca
     6721 cttaaaataa atatattttg tattaccata gaagcaatca gaaaaattac tcctatggct
     6781 acttttttgt ttggatttac tttactcaat ctatttgtat atgcatattt atcaattata
     6841 agcatgatta acttctcttt cctttttgaa gacctaatat gtatcctatt acaccagccc
     6901 ctaaagctgc ttgtgcagag aataataaac tttctatttc tccacttggt ggctcatatg
     6961 gactgctaaa ccatggtttg taatttggat ttatcttagt aatttcactt tcagcttgac
     7021 catctgctcc tccatattca gcacctgagt tgacaagtaa tgggaatata ataagagcta
     7081 ctactaataa aagtaataat atgttagttt ttgttttagc actcattagc tttaactcct
     7141 ttatcattat tttctagtat gcttttttct ccgttttctg taattaaatt atatacaatt
     7201 acagtaagta taccttctgc tattgctatt ggtatttgag tcataaagaa aattcctaaa
     7261 aatttaattg ctgaagccat taccccacct gatgggtctg ggaaagccag tgctaattgt
     7321 attgaagtta ttgtatatgt ggctaagtct cctattgctg ctgcaagaaa tactggaata
     7381 gcattatttc catctttttt ctttaaagcc ttaaatatta ggaatgatac gattggccct
     7441 attatcgcca ttgaaaaagc attagctcct aaagtagtta ttcctccatg tgctaataac
     7501 aatgcttgga atattaaaac tatagttcca agaacaaaca ttacgcttgg tccaaacatt
     7561 attgctccaa gacctacacc agtaggatgt gaacaacttc ctgttactga aggtattttt
     7621 agtgctgata atacaaacac aaatgctcca cataaagcta ataatacttt ctttttaggg
     7681 tcttgcttta ctattttacc tattgatttt aatccgaata agaaaaatgg tataaatata
     7741 actccccatg ctatagacca ttttactggt aagtaacctt ccattatatg cattgcattt
     7801 gatgtaactg gagttaaaat gattaacata agtgcagcta taacccctaa tttaatattc
     7861 tgtttcatct tagtatccct ctctcccttt ctaataatta aaacataata atacatgtct
     7921 gatttattta ataaaataaa aaagcctaac tcgatggtta ggcttctaat tttccacaat
     7981 ctaaatacaa acacataaaa caaacatatc tgtataatta ttataagaaa ctttctccat
     8041 ccccgaagaa attactttaa tattttaggc aggtctcctg acttagcttc atcctactcc
     8101 tcttccttcc catgagatat aaaaaatatc atcatagtgg ctaacaaaag tttcgtctgc
     8161 atcacagtag cgggggctgt aaaggaattt aacctttttc cctattaatc ttgcttaaag
     8221 aacctataat attatatatt taatttttaa attcttctta aattattttc tatataaatc
     8281 attgtatacc ttttctgtga aaatttctac attttttata aattttattc atttttatat
     8341 ttttatgtat ataaattctt ttttgtaagt ttattaattt ctaattatct tctttaaata
     8401 cattgaaact acatcagaaa atctagttat atctcttgaa tatataaaat catttccata
     8461 tattaatctt tcagcttcaa gttctgattc ttttcctgta aatactccta atactaatat
     8521 attttgcttt ctagcttttc tcacttcatt ggctgtatct ctcaaaccaa ctatacccct
     8581 ataagccttt tctcctctta atgttctctc actacttttt cctatcttta catcatttgg
     8641 tcttccatcg ctgagaacta tcaggatttt attttcttca tctctattta ttagaccact
     8701 acatatagat tttattgcca aaccatctct attattacca gcacaaaaat attcaaatat
     8761 attttcacta ttttttatac tatcatcata atctttaaat ctttttaata ttgtatagtc
     8821 taaaaaacta gaaaatccca tcactctatt tggtatgcca acttctgtta gagcatttgc
     8881 aattatgtaa gcttgaattg ccacatttcc ctgatttcta ctttgagagc cacttgcatc
     8941 caataatata tcaataacgt atttcccttt ttcattttct atatctttat aaaatatttt
     9001 attattatta cttctaccaa ctctccaagc tctatttgct aatatagtac cacaatcaga
     9061 atatactcta cttttagcat tttcttctat taaaattctt gatagacttt cttttaatct
     9121 ctttatttgc tgtctataca ttctagcatg ttctctaaat tttcctaaat tattttcttt
     9181 ttgtcttgtt acatatttta gttgaaatac attattacac tcacttctaa gaactccatc
     9241 tgtaaagtgt attctacaac cttcatgaac atttctacaa ttttgtgtct caattttttt
     9301 aatttcacct ttactcaaat aagtttttcc ataataatgt tctatttttg aatatatctt
     9361 atttgcagtg tcttcatcaa catatataac tcggtctgct gaattgctac atttagaatc
     9421 atcaaaatcc cctacacctt ctacaagcat ggatgaagat attgaatcta tatcactttc
     9481 aataatattt tcttcttcat cactataaag ttcttcatac atgaaatcag caaatgtatc
     9541 aaaatttact tctacacttt ctacattatt ttcatcaata agactatttt cttctccatt
     9601 taatatgtat tcaaaataag ttaaatatat aacatctaat gcttttaaaa tctccataat
     9661 atcttgattg gtatctatat ttcttatatc attaactatt cttctagtca tactatctaa
     9721 tgctgggtgc ttgtccatac tataaagtac aaatgtgtat ttaattttat ccataatatt
     9781 atcattgtgt attttggtaa aacgtgaaac aatatcttta taagcatttc ttcttatgtc
     9841 ttctatccct ggcctatctt taatgacctt ttcttcaact attgtattta atataacttg
     9901 aattagaccc agtataatat ctttgttgta tccttttctt attctatttg taagatattt
     9961 tttaactata tcccaatcta catactttct tctagcacct gcaattattg caaaatatag
    10021 acctatttct tttgaagagt aatctttttc tgatatatct atactttcat tgtaatcacc
    10081 agctattgtc catgataagt tattagctct attttcaaat tcataatcat catatatcca
    10141 tttcataatc tcacctatat taaatatgac ttattggaaa cacatctata ctctcccatt
    10201 tattaggtat tctagtttta attacatctc caaccatttc tttctcatat acatcaaaag
    10261 tctttcctgt aagtcccata ttaattgcaa gagttggttt taatcctctt cttatagtct
    10321 taagagatgc cataagacca cgtaaatcaa tagctttact agatatctct ccattttgag
    10381 acttcaattg taaatctaaa aatattcctg caaagtgtat tagtttttct tcatcagcat
    10441 ctgaaaattc attttttaaa atcatcatta acttatcttc ttctatagga ggaatatcta
    10501 ttaccataaa tctagatacc agtgcttcat taagttcttt tgttcctgca tattcataat
    10561 tcatagtccc aataaatctt gttgctggat gtagattgac tctctcatac ccaggtacat
    10621 caattattct tctatagtct aaagctgaat gtaccacaac tatagcatca ttttttgcca
    10681 tattaatttc atcaaacacc ccaaaacctc cattaatagc acactcataa actgagcctc
    10741 ttctaagttt aacttcattg tctataaatg tatctgtacc tataagtgtt gaactgtctg
    10801 tatttatatg aaatgatgta ttccactgag gtctattaaa tatttcccct agattatcag
    10861 caagtaagtt ttttcccgtt gcctttggtc ccgataataa tatattttct tcttctaaaa
    10921 tagctgctat acacatagac aagatatctt taccataaaa ataagtttta gactttgtta
    10981 ctctgtattc taaatctttt tctaatccat aataatttct aaaatacagt acatcttcaa
    11041 taagtttttc atctacccct tgcaccctta gattatctat tatatccata tttttacccc
    11101 ttttatataa atagtatttg tttcatttct tatcaccatt ttagcataaa aggatataag
    11161 ctaaaattga ttttttaatc tccccatttt aagtaaaacc atgcaccatt ttatcactac
    11221 aaaattaaga gtactactta ctgatatttc ttgattttgt tcgtctatac gtatataata
    11281 tatgctgata aattatgagg aaaggatgat tgaaatatgg aatatatgtc ttgcccagaa
    11341 gtagcaaaaa aatggggtat ttctgaaaga agagtacaaa aactatgtga agaaagtcgc
    11401 ataccaggag tttcaaaact cgggtatatg tggctgatac caaagaacgc agaaaagcct
    11461 gttgatggta gaacaaaaag aagaaaggaa gtacaatatg aatagcgttt tgattataga
    11521 tgatgacaaa gaactttgtg ctcttatgaa aaaatgtgtt gagcaagaaa atttatctgc
    11581 tattattgca cattgtggtg cagaaggtct acatttggtc gataaaaata gacacacact
    11641 ctctcttgta attttggaca taatgatgcc agatatagac ggttttcaag ttctgaaaaa
    11701 aattagagaa acaagtaata ttccagtaat tatgcttact gctaaaaatg acgaggatga
    11761 taaagtttcc ggactacgtt taggtgctga cgattaccta acaaaaccgt tcagcataaa
    11821 cgaacttatg gctcgtgtca attctcttat tcgtcggtat actatgttaa accctgcttt
    11881 tataacagac acagattgca taataataaa tggcatgatt attgacaaga caaaccgaat
    11941 tgtttctgtc aataatattc ctgttcaact tacaagcaaa gaatttgatt tacttgcttt
    12001 tctggcttct aataagggac aggtgtttac caaaaaacag atttatacac aagtatggga
    12061 agaagaatat gcttttgacg atagtaacat catgtctttc atcagtaaat tgagaaaaaa
    12121 gattgaacca gaccccaacc atccatttta tattttgaca gttcgtggtg tcggttatcg
    12181 ttttaataag gaggcttaac atgaatacaa gtgtctatct gcttttgata ttggttctta
    12241 gcctgattat tatagcgtac cttgtttctg tcctgctacg tgtccgaata caacttacac
    12301 ttataaaaga tgctttagag gatataaaaa atggaaacct taatcgacgt attttaacag
    12361 atgaaaacga cattacaaaa caaatttgct atgatattaa cgaaatagca atcaatagcc
    12421 aatttcaact tattcagcaa aaacaatcag aacaagccta caaacagcta atgacaagtc
    12481 tctcccatga tgtaaaaact ccacttgctt ctttggtcgg ttatttggaa gcagtagaaa
    12541 gtaaaattgt tgtaggagag gaaaaagacg agtatatcca tgttgcgtct aataaggctc
    12601 attacttaaa gaattttgta gaaaatctat ttgaatgggt aaaattggat tctaaggaac
    12661 aagtttttca ttttgatatt tttgacttga atgaattatc ccgtaatatt atatctgatt
    12721 ggatacctgt tttagaaagc agtcattttg aatatgaatt tgatatacca gaaatagagt
    12781 acttcttacg tatagacgca aatgcatata cccgtatcat taataaccta ttacaaaata
    12841 ttattaccca tagtagtggc aacaaaatga cattgagaat ttttgaaaac aaagagcaag
    12901 ctcaaattat aataacagat aatgggaaag gtatatcttc agacaatctc ccacatattt
    12961 ttgaaaggtt gtaccaatgc gaccattcac gagcttcaaa gggaaatggt ttaggcttgg
    13021 cgattgcaaa ggaacttatt aacgctcata agggaaatat taccgccaac agcactcccg
    13081 gtatgggaac agaatttaca atattgcttc ctaaagccct gtaaaagtac gaggctttct
    13141 tactctaaaa caagataaaa gcaagattat ggcaaggttt tggcaaggtt catgttttat
    13201 aattctaatt gtagttgatt ttgacgttgt atcaactatc ttttgtagaa acaaatttat
    13261 taaaagtgag gaaattatat atgaatgatt ttgtgattga aacaaagcaa cttacaaaaa
    13321 tttatgggaa tcaaacagta gttgacaaag tcaatctcca tgtaaaaaaa ggccgaatat
    13381 atggtctgtt aggacgcaac ggagctggga aaaccacaat tatgaaaatg attttaggat
    13441 tgacttcaat cacgtatggc gaggtagatg tatttggaga gaatattaag gaacgtgaaa
    13501 aacaagtata tccccgtatc ggtgcaatta tcgaaacgcc aggattttat cctaatctga
    13561 caggaacgga gaacttggag atttttgcaa aactgcgtgg tacagccgcc cctaattctg
    13621 taaaaagagc attggaaatt gtaggcttac cttataaaaa taaaaagctg tttagtaaat
    13681 attcacttgg catgaaacag cgacttggta ttgccaacgc tatcctgcat gacccagaac
    13741 tgttagtttt agatgagcca accaatggtc ttgaccctat tggtattgcg gagatgagaa
    13801 agtttattag ggacttgagc gttgagcatg gaaagacaat tcttatttcc agtcatattc
    13861 tttcagaaat ctcattgttg gctgatgata ttggaattat cgaccacggt gttcttttgg
    13921 aagaaagtag tatgagtgaa ctagaaaaga aaaacagtaa atatatcctg ctacaagttt
    13981 cagatattcc gaagacatca cttattttag agcgtcaatt taacacgaag gattattccg
    14041 ttcaagatga ctacacgtta cacctttata acactaatct ggatatgggt gaaatcaata
    14101 aagcacttgt aatgcagaat gtaactgtta ttagttctca actttgtaat gatactttag
    14161 aggactactt taaaaaaatc acaggaggag agggcattgc ttaaacttat tcaaacagaa
    14221 tttcttaaac tgcgtcgtag gaaacttatt tggctgatgt tgttgtctgc tctcattatg
    14281 ccgtttttcg cactactata cttcaattat tttggtaaaa caggtgttga gccaataaag
    14341 ttttataaat ggtctgcatt tggttataca ctttggatta ttttgcctgt tgttttgggt
    14401 atattttgca ccatgcttat acacgaagaa aaccagtatg atatgctcaa acagctttgg
    14461 attgtaccta ttagtaaaat gggatacttt tttagtaaat ttttcgttgt tttgatttac
    14521 tctatttgtt ttatgctgat tacagccgtt gcttctgtgt tatttagtgt actttctgga
    14581 tatgtcgtat ttagctgggc aagcatttta tatttgttga aaaaatgttt agaaattggt
    14641 gtaatcactg cttttgtaat gttgccgatt ttggcaatcg ctacatctca aaaaggatac
    14701 attctcccaa tttgtatcac attggtatat gccttttccg gttttgttat aatgacaata
    14761 aatatgtatt tacacccatt atccagtatg ggagttatta tcatgagaaa taaagacatt
    14821 ccaggtctta tattttcaca ggaaattaat gtcccattag catttctttg tatttgtatt
    14881 tggagtattg tatcagtatt gtttgcaaat attgcactag gaagaagaaa gtgaggtgta
    14941 gataatgtgg aaattacttt gggctgaatg tcaaaaaatt cgtcgttcaa aaattgtttg
    15001 gattacagtt tttgcatcca ttatgatagc agtcatagtt tttgcagggg ggcaggatgt
    15061 atataatgac ccagatttac attatggctt aaagagcgtt tatgacggtt cacggtatat
    15121 agacaatgca ggttggtata tggacgcagt acaaccttgg tcaacttttt ttgttcttcc
    15181 tgctgtcatt gccctattag gaagctatat tatttgtcgt gaagaagagg aggacactat
    15241 taaatccctg cgtcttattc ccataaatga aacaaattta accatagcaa aaatgattat
    15301 tacttttata ttcagtatac ttctttattt gttactcttt actataacat ttttgactga
    15361 atccgtttta catttttccg atttatcgac aaaattggtt ttaagttgca tgaaagagta
    15421 ttttcttgat ggcataggtg tattctttgc aatttctccc attattgcct tggtatcgcg
    15481 catgaaaaaa ggatattggc ttgcattagt attcacagaa gtttattcta ttgctggact
    15541 atttgcgggt atgtcaaatg tcttacaaac cttttttcct attgcggcaa tatttaatat
    15601 ttctggatac tatataacta ctggagaaaa aattatgggg agtatcataa gtttattact
    15661 ttgtgcctgc ctttctgcat ttatacttaa agggctaaaa cacaatgaaa aaaattgaaa
    15721 taggtatatc aaaatgaaaa agataaaaaa actgattatt ctaattgtat tcttgtttct
    15781 ttttggcatg ttacactgtt atactgaatg gaaattcaac aataacccac ctaaaggggt
    15841 aatagaaaga ataaatgagt ggactggatt agtaacttat gttaattata gtgaatgtaa
    15901 tattagcaag ttattgtttc gtattttaat actataactt taaatatttg gttttaatct
    15961 tccaaacgaa tataaaaaaa ctgtcacaga ggcaacatat ttttgaatat ttataaagtg
    16021 gtagttttga ttttcaaagc taccgccttt tcttctatat aagcaaactt atcctcaaca
    16081 aagtgtaaaa catggtacat tttaagaaaa aagtaccaca gacacaagca ataaaagaaa
    16141 cgccgagaac ctacaaaaac gtagtgctta tgcagattta cgacgccttc tattttctca
    16201 accgtcttaa tgaccttgta caaaagaaat ttttctaata ttttttataa tcttatcttg
    16261 tgatgttttt tatgtataaa tgacttaata acaaatccaa taaaaattat ggatattggt
    16321 ataattagaa cgaggaattt ataatcatta taatgtgaca ttattcttac ccaactctca
    16381 gaaaaaatat atcctatact gattaatgaa gtattccata tggttattcc cacgatagat
    16441 gatattacaa aagttataat attttgccct gctatacctg ctataaaaga tatgtatgtt
    16501 ctacataaag ggattaatct acatacacaa acagaaatag aagagtattt attaaaataa
    16561 tcttgagatg caaatattcc tttctttgcc tttggacata tctctattat tttatttatg
    16621 atagatttac ctccccaatt tcccactgta taacaaaata tcgaaccaag tatacctgca
    16681 attatactta aaattaaaat tgtcagaaat ccaaaatgat ttcttgcagc aattgctcca
    16741 cataaaggta aaacaacttc gctaggtaat ggaaaacaag catactcaat cataattaat
    16801 acaaatacag agattaatcc atattgtaaa ataaaactat tgattacaga cacttactta
    16861 tctatctcct ttcttattta aaggttttaa gggtacatgt tctaaggatt ctcaccctat
    16921 atttaaagaa tcaatctctt taaactatta tatgtattta cacaaagcat ttataacata
    16981 ctttaaaaat agtaccttaa aataagaaac ttaataaata aaaaaagatt acgtggctac
    17041 gtcctactct cccaggcagt ttcccaccaa gtaccatcag cgctagagag cttaacttct
    17101 gtgttcggaa tgggaacagg tgtatcctct ctgctattgt aaccacataa tctttatgct
    17161 taatatttcc attaagtttt taataagttt atagaa
//
LOCUS       DAMKNB010000074        16790 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.078, whole genome shotgun sequence.
ACCESSION   DAMKNB010000074 DAMKNB010000000
VERSION     DAMKNB010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 16790)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16790)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16790
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.078"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            286..744
                     /locus_tag="PC494_002785"
     CDS             286..744
                     /locus_tag="PC494_002785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDF3913275.1"
                     /translation="MEFINFVSDKVIDLKMDCKTKEDFFKEIHNKVFDLGFVKEEFGE
                     KILARENVFPTGLNLGDYGVAIPHTDAEYIKEQFISVCTFNEPVVFSSMEDQDEKVPV
                     NLAFVLGLNQPHSQLSVLTELMGIMQNKELVDKLMSSTDKEEVLKTLKSL"
     gene            805..1080
                     /locus_tag="PC494_002786"
     CDS             805..1080
                     /locus_tag="PC494_002786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDF3913276.1"
                     /translation="MKKILVACGAGIATSTVVCDKVERLVKENNIQAEVIQCKIAECA
                     TKQEGADLIVSTTILPTTYNIPAIKATAYITGVNTAALDKKILDALK"
     gene            1139..2413
                     /locus_tag="PC494_002787"
     CDS             1139..2413
                     /locus_tag="PC494_002787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012951111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HDF3913277.1"
                     /translation="MDKLLAVVQYILNMGPTVILPITIVVLGMIFRIKFTKALKSGLT
                     IGIGFVGINLVVNLLTSTLGPAAQGMVERFGLNLTVIDVGWPTTASATWASPVAPILI
                     PVCLLVNLLLLYFNKTKILNVDIWNYWHFIVAGAVGYIVTGSYVWAIFCAILMELLVL
                     FIAEKTAKNVQEFYDLEGIALPTGSTASFAPLGYLVGKFVEKIPGINKIQADPDSIQK
                     RFGIFGEPMMMGIILGIILGALAGYDVAGIFNVGISMGAVMLLMPRMVRILMEGLIPI
                     SESIRDFLQAKYGDRELYIGLDAAVATGHPAVISTALILVPITLFLAVILPGNKVLPF
                     GDLATIPFYMAFIVCFRKGNIVQSVITGTIVIAISLYMATNFADVHTQLLQQANMMPE
                     GTTMVTSIDTGGNLLKWGILKLSQLVSSFGIF"
     gene            2543..3595
                     /locus_tag="PC494_002788"
     CDS             2543..3595
                     /locus_tag="PC494_002788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HDF3913278.1"
                     /translation="MKAAVLHGTNDMRFEDIEIKPCESDEVKIKVMAAGICGSDPPRV
                     LKHWKYPVPAIPGHEFSGVIAEVGKDVKNVKVGDRVVAIPFIPCNECEYCKRGLFSLC
                     DDHGMLGAKSFGAFAEYVNIKATNVLPIGDMDFEDAAMIEPLAVAMHGVLNIGVQVGD
                     TVAVMGSGTMGQLVIQGLKIAGAGTIIAVDISDNKLRESKELGADIIINAKDINPVEK
                     IKELTGGKGVDIALECAGSKITQEQCLLITKKKSKIGFLGIAYSDITLSEEAFENIFR
                     KELELKGFWNSYSAPFPGQEWTKGINLVNEGKIKLKEMVSHRFSLEDTYKAFEMIRDR
                     KEEFNKILILPQGVEK"
     gene            3595..4626
                     /locus_tag="PC494_002789"
     CDS             3595..4626
                     /locus_tag="PC494_002789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012986518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding dehydrogenase"
                     /protein_id="HDF3913279.1"
                     /translation="MKAVVKTKPGYDNVEVLEVEEPKATGDKVKIKVEYSGICGSDIH
                     SFKGEYANIKAPVTLGHEFSGIVVEVGEDVKNIKVGDRVTSETTFATCEKCIYCETKD
                     YNLCPTRKGIGTQVNGSFAEYVLSREESIHVLPENVSLLSAALTEPLACCVHAALEKT
                     TIESSDTVLIIGPGPIGLLLAQVVKSQGATVIMSGVTKDKERLEIAKNLGVDRTVNVM
                     EESLADVVNEMTDGNGVNKGFDCSGFMPAVNEALRLLRKKGTFVQVGIFAKKLNEMDQ
                     EAIIQRELQYIGSRSQKPSSWITALDLMASGKVNTEALVTRTVGLDEFKEGITALMNG
                     EEIKVAVKS"
     gene            4718..5530
                     /locus_tag="PC494_002790"
     CDS             4718..5530
                     /locus_tag="PC494_002790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HDF3913280.1"
                     /translation="MSTLRDHSNNIRKNIIKMVAEAKSGHPGGSLSIADMLTVLYFDK
                     MNVCAENPKMADRDRFVLSKGHAAPALYATLAEKGFFPEEELITLRKFGSKLQGHPDM
                     KKVAGIDMSTGSLGQGLSAANGMALAGKLDNKDYTVYTILGDGEIQEGQIWEAAMTAS
                     HYKLDNLIAFVDLNGLQIDGSNEEVMNVNPVDDKFKSFGWNVIVINGHSFEEIGNAVD
                     EAKKVTGKPTVIIAKTVKGKGVSFMENNAAWHGTAPNAEQAEQALKDLEGGL"
     gene            5533..6453
                     /locus_tag="PC494_002791"
     CDS             5533..6453
                     /locus_tag="PC494_002791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase family protein"
                     /protein_id="HDF3913281.1"
                     /translation="MGIATREAYGQVLKELAENKDIVVLDADLGKATKSISFKEVAPD
                     RFFDMGIAEGDMIGTAAGLATCGKIPFASTFAIFAAGRGYEQIRNSVAYPNLNVKIAA
                     THAGVTVGEDGGSHQAIEDISLMRGIPNMVVLNPADALEARQAILASIDYNGPVYIRL
                     GRAATPDVNSENYKFEIGKGTVLREGSDITVIATGIMVAKALEAAEELAKEGINVEVV
                     NISTIKPLDEALIKETAKKTGKVVTAEEHSIIGGLGSAVCEALAETKDVVVRRIGVKD
                     VFGQSGTPADLLKHYGLTTEDIVKNIKELL"
     gene            6628..7074
                     /gene="rpiB"
                     /locus_tag="PC494_002792"
     CDS             6628..7074
                     /gene="rpiB"
                     /locus_tag="PC494_002792"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose 5-phosphate isomerase B"
                     /protein_id="HDF3913282.1"
                     /translation="MKISIGCDHGGYELKEYIKENLINKGIEVEDVGTNSKESVDFPI
                     YAKKVSQNVQSKKSDLGILCCGTGIGMSIAANKFKGIRAAVVSDCFSAKATREHNNTN
                     VLCLGERVIGKGLAMRIVEEWLNSSYNGERHARRLQMIDDIEKENL"
     gene            7104..7769
                     /locus_tag="PC494_002793"
     CDS             7104..7769
                     /locus_tag="PC494_002793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HDF3913283.1"
                     /translation="MSIICASIMCADQMKLKEELEALEEAGVKLLHCDVMDGIFVKNL
                     AMGPELLKSISENTTIPLDIHLATETPDKYIDMMSYIKPKYISFHVESSTNVKADIQK
                     LRNYGIGPVLAISPQTSVDKIEEYISLVEGILVMTVNPGFAGQKFNLSVLDKLDKLTE
                     ILKDYDNPPFIEVDGNINKDTIKLMNGKKVDIYVVGTSALFNDKPPISYKDKIEELKE
                     SIK"
     gene            7879..9381
                     /locus_tag="PC494_002794"
     CDS             7879..9381
                     /locus_tag="PC494_002794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomannomutase/phosphoglucomutase"
                     /protein_id="HDF3913284.1"
                     /translation="MGDLYKLQNGTDIRGIAYENDSKEVNLTVEEVKKIAKAFHIWLK
                     EKTKKDKVTVAIGTDSRITGSQFRSTVIETLTNDDCNVIDCEIATTPAMFMTTIMDGY
                     NSDGAIMITASHLPYYYNGLKFFTESGGLEKTDIKEMLDIAVKNDSVDYEEVNKKGEV
                     IVKNLIEDYSNLLIDKIRKGVNSSKNYEKPFSGLKILVDAGNGAGGFFAEKVLHILGA
                     DTTGSQFLNPDGMFPNHIPNPENKEAMESICKAVLDNKSDLGIIFDTDVDRAAIVGKN
                     GKPINKNALIAVISSIVLEEHPKTAIVTDSITSEGLAKFINELQGRHHRFKRGYKNVI
                     NEAIRLNSEGEECHLAIETSGHAALKENYFLDDGAYLIAKILIKVAKLSLEGKTIEEL
                     IENLEEAQEEKEVRIGINKEDFRPYAEDILKDLDSHVKSIDGWSVAPNNFEGIRVNCD
                     ESNGDGWFLLRISLHEPLLALNIESNKIGGAEQIYSKLKLFLEKYDLKGL"
     gene            complement(9693..11285)
                     /locus_tag="PC494_002795"
     CDS             complement(9693..11285)
                     /locus_tag="PC494_002795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HDF3913285.1"
                     /translation="MVTKLKNLIINDSKAKFILLLLLFLLVSILFEAVYDLNNNFSYN
                     INCYYKEFALPYFYFFGTPVHLSKVELEFVCIGIILSSFLLTILCFTLYKKNKQTKVK
                     FLENVISLFSKVKIELTLILTLILLTLRFHAFTSNKMFYNTNLIIYNFIIISIVYIIY
                     ENIKYNNYNLKDMSITYVFFSNLLSMYNKKTINKKLAIVFLISIVVQAIIQYLVLIFF
                     MYIYYAEAIAIVILFTLVNTVFHFYIYNFLSVKFNYINNISKNIKNIENGNLKYKLKV
                     IGDDEISTLAKSINNITGGLETAVDANIKNERMKAELITNVSHDLKTPLTSILSYVDM
                     LKNNDFDRETINDYINILDKKSQRLKLLIDDIFEASKLSSGDVEFNITKTDIRELLIQ
                     SIVEFEDKIQNSSLDFIIETPEYAVFTMIDGKKTWRVFENLICNILKYSMPNTRVYID
                     MFIKEENIILTFKNISNDKLNLKPEELIERFRRGDISRKTDGSGLGLSIAQNIIELEN
                     AHMEIIIDADLFKVMLTFRRVN"
     gene            complement(11254..11970)
                     /locus_tag="PC494_002796"
     CDS             complement(11254..11970)
                     /locus_tag="PC494_002796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF3913286.1"
                     /translation="MNQNILVVDDDREIVDAIEFYLRPDNFNVLKAYDGLEALDILIE
                     NDIKLIIMDVMMPNLDGLKTTLKIREKRNIPIILLSAKSEDMDKIIGLNMGADDYITK
                     PFNPLELTARVKSQLRRYINLGDFSNTNNSNDTNYILKSGGLELNTDTKIVSLDGEEI
                     KMTPLEYKILTLLMSRKGKIFSSHEIYENVWNEDAYSCERTIAVHIRRIREKIEINPK
                     EPKYLKVVWGIGYKIEKLNY"
     gene            complement(12510..13310)
                     /locus_tag="PC494_002797"
     CDS             complement(12510..13310)
                     /locus_tag="PC494_002797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIG-L family deacetylase"
                     /protein_id="HDF3913287.1"
                     /translation="MTFKNKKFTINKYKILSIILVLCLILTAFSSYVNYSHKKFKDYV
                     VFYVQHQDDEVLWAGSAIVNAIKERGKNHVFVVLVSTGCGISVFDKYKKYENLTNIQK
                     SEYRNREFLASLNSLGVIRENIILLPETNTNGNTDFNYMEKIALTFEEKFKNVTHIAH
                     TYKLDDHLQHLKNGSVIQNLYNAGKIKDAKYFVKPKFADKITFNNKIVYKAHSTEDYE
                     KVKNACQQYKIVDELEYREGIGYKSDHKSFDKLLNNKDVPAILHTPNL"
     gene            complement(13624..14355)
                     /locus_tag="PC494_002798"
     CDS             complement(13624..14355)
                     /locus_tag="PC494_002798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3913288.1"
                     /translation="MNIFDILRDYLLVQVDKYNLNMDMISIVSKSLSSKEAIGNTKRK
                     DFPIIVGKEIMLEADFKGAKGQAFTSTPSTFEGSLKDILSLDLHDNPHDRSLFIASLN
                     AVMKYLGKTDRTIHCKNNEPEVCAKKFPEFIKMEFGNPKVAIIGYQPAIIDNIKDFFE
                     TRVLDLNPEFVDTIQYNVKIEDGIRDYEDVISWADLVICTGSTLCNNSIINFLSLNKP
                     VYYYGTTIAGASNILGLERLCFCSK"
     gene            complement(14342..15037)
                     /locus_tag="PC494_002799"
     CDS             complement(14342..15037)
                     /locus_tag="PC494_002799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDF3913289.1"
                     /translation="MLKIKNLSLDLPNFKLQENSLNINNHEYFVLLGASGSGKTLFLE
                     TLAGRYPSAKGNVSYKENLISNLPPENRNIGFVYQNFELFPNMSVEDNIRFPLKLRKI
                     PIDEQILKANHLSKLMQIEDIKNRYPKNLSGGEKQRVAFARALIAEPDILLLDEPMSS
                     LDYITKKHISKILKDVYIKYKPTVIHVTHDISEAMFFAHKIGIMNNGKINHIFDLNEE
                     IKNKGESFFYEYI"
     gene            complement(15039..15830)
                     /locus_tag="PC494_002800"
     CDS             complement(15039..15830)
                     /locus_tag="PC494_002800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF3913290.1"
                     /translation="MKNKFFTTLLTGFFAIVFLFIVSPLLMLIIKGISYVPICLKSVE
                     VQYAITLSIKTSLISTIVCLLLAIPVAYFLHITKLPFKKLIIQIINLPMSLPHLVSGI
                     ALLLLFGRMGIGDSIYKIFKLDFIFTKQGIVLAQIFVNLPLTIKILHTSLNESNEKMI
                     FVARTLGCNSWEAFRFIILPNLKTGIISATVMTWSRALGEFGAVAMIAGSTRMKTEII
                     PTSIYLNMSTGDIDIAIGIAVILIFISLTCLMLFEIFFNREVDKN"
     gene            complement(15840..16652)
                     /gene="modA"
                     /locus_tag="PC494_002801"
     CDS             complement(15840..16652)
                     /gene="modA"
                     /locus_tag="PC494_002801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdate ABC transporter substrate-binding
                     protein"
                     /protein_id="HDF3913291.1"
                     /translation="MFKKLSVLALAMIISLSITACNSKENKANDESNTKVTTADDSKE
                     KETLFVYSGAGLKKPMDEIAKKFEKENNVKVEYSYAGSAQLIAQIETSHKGDVFIVGS
                     EPIYSKAFEKELVGEHKTVAHHTPAIVVPKGNPANIQKLEDLNKDGVKLILGDKESNA
                     IGKTTQKILEKNNLKSINDNVVSTAATVNEMIVQLTSSKADATIATKDSVFGNEDVEV
                     IEIAQDKNIDQLISAGIVNYSDKKDLANKFINYIESDEAKQIFKKYGFEPVK"
BASE COUNT         6394 a         2066 c         2706 g         5624 t
ORIGIN      
        1 ataaaaaacc atttgtaaaa aacaaaaaaa tcatttctct aacaaaaaaa accacaaaaa
       61 atataaaaaa gtatggctag ttaagtgatt aacaagtaaa aattaaaata aaaatcaaaa
      121 aaaatttatc aatgaaagtc agctaaaatc ctggaagaga gcattatttt tgggaaaaca
      181 ttttcttttg tttcacaaaa aaagccactt tttggcacac aacatgcttt atataaagtc
      241 aagaaaaact aaggtataag acaaaggcaa ttaggaggtg taaatatgga gtttataaat
      301 tttgtaagtg ataaagttat agaccttaaa atggattgta aaacgaaaga agatttcttt
      361 aaagaaatac ataataaagt ttttgattta ggctttgtaa aagaagaatt tggagaaaaa
      421 atattagcaa gagaaaatgt atttccaaca ggtttaaatt taggtgatta tggagtagca
      481 ataccacata cagatgcgga atatattaaa gagcaattta tatcagtctg tacttttaat
      541 gaaccagtag tatttagttc tatggaagac caagatgaaa aagtacctgt aaatttggct
      601 ttcgtattag gacttaatca accacacagt caattatctg tattaacaga attaatggga
      661 attatgcaaa ataaagagtt agttgataag ttgatgagtt ctactgataa agaagaagtt
      721 ttaaagacac taaagtcttt ataaaaataa aaaagtacta aaaataaaaa atataaaaat
      781 aaaaattatt aggaggaaat aaaaatgaaa aaaatattag tagcatgtgg agcaggaata
      841 gcaacatcaa cagtagtttg tgacaaggta gagagattag ttaaggaaaa taatatacaa
      901 gcagaagtta tacaatgcaa aatagctgaa tgtgcaacaa agcaagaagg agcagattta
      961 atagtatcaa caactatact accaacaact tataatatac cagcaataaa agcaacagca
     1021 tatataactg gagtaaatac agcagcatta gataaaaaaa tattagatgc tttaaaataa
     1081 tcctatcata gatacattga aataatattt tataaaacag aaaaaggagg atttataaat
     1141 ggataaatta ttagcagtag tacaatacat tttaaatatg ggaccgacag taatactacc
     1201 aataacaatt gtagtactag gaatgatatt tagaattaag tttacaaaag ctttaaagtc
     1261 aggtcttaca attggtatag gatttgtggg tataaactta gttgtaaacc tattaacatc
     1321 aacactaggg ccagcggctc aaggaatggt tgaaagattc ggacttaatt taacagtaat
     1381 agatgttggt tggccaacaa cagcatcagc aacatgggct tcaccagttg caccaatatt
     1441 aataccagtt tgtttattag taaacttact attattatac ttcaataaaa caaagatatt
     1501 aaacgttgat atatggaatt attggcactt tatagtagca ggtgcagttg gatatatagt
     1561 aacaggaagt tatgtttggg ctatattctg tgcaatacta atggagttat tagtactgtt
     1621 tattgcagaa aagacagcaa aaaatgttca ggagttttat gatttagaag gtatagcatt
     1681 accaactggt tcaacagctt catttgctcc acttggatat ttagtaggta aatttgttga
     1741 aaaaatacca ggaataaata aaatacaagc agacccagac tctatacaaa aaagatttgg
     1801 tatatttgga gaaccaatga tgatggggat tatactaggt ataatacttg gagcacttgc
     1861 gggatatgat gtagcaggaa tattcaatgt aggtatatca atgggtgcag taatgttact
     1921 tatgcctaga atggttagaa tattaatgga aggtttaatt ccaatttcag aatcaataag
     1981 agatttctta caagcaaaat atggagacag agaactttat ataggtctgg atgcagcagt
     2041 agcaactgga catccagcag ttatatcaac agctcttata cttgttccta taactttgtt
     2101 cttagcagtt atactaccag gaaacaaagt tttaccattt ggagacttag cgacaatacc
     2161 attttatatg gcatttatag tgtgttttag aaaaggtaat atagttcaat cagttataac
     2221 aggaacaata gtaatagcta tatcacttta tatggctaca aactttgcag atgttcatac
     2281 acaattatta caacaagcaa atatgatgcc agaaggaaca acaatggtta caagtataga
     2341 tacaggtgga aacttgctaa aatggggaat attgaaatta tctcaattag tttcttcatt
     2401 tggaatattc tagtatgtag ttaatagaga ttactctttt ttagtaaagt atgcgaaaat
     2461 ttaacattta gcagctacta aaaaagagta atatttttta taaattttta aaaatacaaa
     2521 atacaagagg aggagattta tcgtgaaagc agcagtatta catggcacaa atgatatgag
     2581 atttgaagat atagaaataa aaccatgtga aagtgatgaa gtaaaaataa aagttatggc
     2641 agcaggaata tgtgggtcag atcctccaag agtattaaaa cattggaaat atccagttcc
     2701 agctatacca ggacatgagt tttctggagt aattgctgaa gttggtaagg atgtaaaaaa
     2761 tgtaaaagtt ggagatagag tagttgcaat tccttttata ccttgtaatg aatgtgaata
     2821 ttgtaaaaga ggattatttt cattgtgtga tgaccatgga atgttaggag ctaaaagttt
     2881 tggagctttt gcagagtatg taaatataaa agctacaaat gtacttccaa taggagatat
     2941 ggactttgaa gatgctgcaa tgatagagcc actagcagtt gctatgcatg gagtacttaa
     3001 tataggtgtt caagttggag acactgtagc cgtaatgggt agtggaacaa tggggcagtt
     3061 ggtaatacaa ggacttaaaa tagcaggggc aggaacaatt atagcagttg atatatctga
     3121 taataaatta agagaatcaa aggaattagg ggctgatata ataattaatg ctaaagatat
     3181 taacccagta gaaaaaataa aagaacttac tggtggaaaa ggtgttgaca tagctcttga
     3241 atgtgcaggt tcaaaaataa ctcaagaaca atgtttactt ataactaaaa agaaaagtaa
     3301 gataggattt ttagggatag catattcaga tataacttta tcagaagaag catttgaaaa
     3361 tatatttaga aaagaactag aattaaaagg tttttggaac tcttattctg caccatttcc
     3421 aggacaagaa tggactaagg gaatcaatct agttaatgaa ggaaagataa aattaaaaga
     3481 aatggtatct catagattct cacttgaaga tacttacaaa gcatttgaaa tgataagaga
     3541 tagaaaagaa gaatttaaca aaatattaat tttaccacaa ggggttgaaa aataatgaaa
     3601 gcagtagtta aaactaaacc aggctatgat aatgtagaag ttttagaagt agaagaaccg
     3661 aaagctacag gagacaaggt taaaataaaa gtagaatata gtggtatatg tggttcagat
     3721 atacattcat ttaaaggtga atatgcaaat ataaaagccc cagtaacatt aggtcatgaa
     3781 ttttctggaa ttgttgtaga agtaggagaa gatgttaaaa atataaaagt aggagataga
     3841 gttacatcag agactacttt tgcaacttgt gagaaatgta tatattgtga aactaaagat
     3901 tataacttat gcccaactag aaaaggtatt ggtactcaag taaatggaag ttttgctgag
     3961 tatgtattat caagagaaga aagcatacat gtacttcctg aaaatgtatc tttattatca
     4021 gcagccctta cagagccact agcttgttgt gttcatgcag ctcttgaaaa gactactata
     4081 gaaagttctg atacagtttt aataatagga ccaggaccaa ttggtttatt attagctcaa
     4141 gttgttaaat ctcaaggtgc tacagttata atgtctggtg ttacaaaaga taaggaaaga
     4201 ttagaaatag ctaaaaatct tggagtagat agaactgtaa atgtaatgga agaaagtttg
     4261 gcagatgtag tgaatgaaat gactgatgga aatggagtaa acaaaggatt tgattgttct
     4321 gggtttatgc cagcagttaa cgaagcctta agactgctta gaaaaaaagg tactttcgta
     4381 caagttggaa tctttgctaa aaaattaaat gaaatggacc aagaagcaat aatccaaaga
     4441 gagttacaat atataggaag tagatctcaa aagccaagtt cttggattac agcattagat
     4501 ttaatggcaa gtgggaaagt aaatacagaa gctttagtta ctagaactgt tggtttagac
     4561 gaatttaaag aaggtattac agctttaatg aacggggaag aaataaaagt agcagtaaaa
     4621 tcttaaaaaa acatttgtat tattttaaaa aaaattgtaa aatctactgt aggataaaaa
     4681 aatgtaaggt cttaaaaaat aacaggagga agaaagtatg agcactctta gagatcattc
     4741 taataatatt agaaaaaaca taataaaaat ggttgcagaa gctaaaagcg gacatccagg
     4801 tggttcatta tcaatagctg atatgttgac agtattatat tttgataaga tgaacgtatg
     4861 tgcagaaaat ccaaaaatgg ctgatagaga tagatttgtt ctatcaaaag gtcatgcagc
     4921 accagcttta tatgctacat tagcagaaaa aggatttttc ccagaagaag aattaataac
     4981 actaagaaaa tttggttcta agttacaagg tcacccagac atgaaaaaag tagcaggaat
     5041 cgatatgtct actggttctc ttggtcaagg gctatctgca gcaaatggta tggcacttgc
     5101 aggaaaatta gataacaaag actatacagt atatactata ttaggtgatg gagaaatcca
     5161 agaaggtcaa atatgggaag ctgcaatgac agcatcacat tacaaattag ataatttaat
     5221 tgcatttgtt gacttaaatg gattacaaat agatggttct aatgaagaag taatgaatgt
     5281 aaatccagta gatgacaaat tcaaatcttt tggatggaat gtaatagtaa taaatggaca
     5341 ttcttttgaa gaaataggaa atgcagttga tgaagctaaa aaagttacag gaaaaccaac
     5401 tgtaataata gctaaaacag taaaaggtaa aggtgtttca tttatggaaa ataatgctgc
     5461 atggcatgga acagctccaa atgcagaaca agcagagcaa gcattgaaag atttagaagg
     5521 aggtctatag gaatgggaat agcaactaga gaagcttacg gacaagtgtt aaaagaactt
     5581 gcagaaaata aagatatagt agtattagat gcagatttag gaaaagctac aaaaagtata
     5641 tcatttaaag aagttgcccc agatagattt tttgacatgg ggatagcaga aggtgacatg
     5701 attggtacag cagcaggtct tgctacttgt ggaaaaatac cttttgcgag tacttttgca
     5761 atatttgcag caggaagagg ctatgagcaa ataagaaact ctgtagcata tccaaattta
     5821 aatgtaaaaa tagcagctac tcatgcaggt gtaacagtag gtgaagatgg tggtagccat
     5881 caagctatag aggatatatc tctaatgaga ggtataccaa atatggttgt attaaatcca
     5941 gcagatgctt tagaagcaag acaagctatt cttgcatcta ttgattataa tggacctgtt
     6001 tatataagat taggtagagc tgcaactcct gatgtaaaca gtgaaaatta taaatttgaa
     6061 ataggaaaag gaactgtttt aagagaaggt tctgacataa cagtaatagc tacaggaata
     6121 atggtagcaa aagccttaga agcagcagaa gaacttgcta aagaaggtat aaatgtagaa
     6181 gttgttaata tatctacaat aaaaccatta gatgaagcac taataaaaga aactgctaag
     6241 aaaactggaa aagtagttac agcagaggag cacagtataa taggtggttt aggttcagct
     6301 gtatgtgaag ctttagcaga aactaaagat gtagtagtta gaagaattgg tgttaaagat
     6361 gtatttggtc aatcaggtac accagctgat ttattaaaac actatggttt aactacagaa
     6421 gatatagtaa aaaatataaa agagttgtta tagatataaa tatatctaaa taacaaattg
     6481 atttgacata agtcaattaa agctgtctta aaaatagaaa gaaatttcta caatgggaca
     6541 gctttatttt tacaatactt tatttttatg ataattataa aatagtctga aagtaatcaa
     6601 aaaaattata aaaagaggtg ctatttaatg aaaatatcta ttggatgtga ccatggtggt
     6661 tatgaattaa aggaatatat aaaggaaaat ttaataaata aaggtataga agttgaagat
     6721 gtgggtacaa attcaaaaga aagtgtagat tttccaatat atgcaaaaaa ggtaagtcaa
     6781 aatgttcaaa gtaaaaaatc tgatttaggc atactttgtt gtggaacagg aataggtatg
     6841 tctattgcag caaataagtt taaaggaatc agagcagctg ttgtttctga ctgtttttca
     6901 gctaaggcaa ctagagaaca caataataca aatgtacttt gtttagggga aagagttatt
     6961 gggaaaggat tagcaatgag aattgttgaa gaatggttaa attcaagtta taatggagaa
     7021 agacatgcaa gaagattaca aatgattgat gatatagaaa aagaaaattt ataaatatat
     7081 aatttataac aagggggagc gttatgtcta ttatttgtgc ttcaataatg tgtgcagacc
     7141 aaatgaagtt aaaagaggaa ttagaagctc ttgaagaagc aggtgtaaaa ttacttcatt
     7201 gtgatgttat ggatggaata tttgttaaaa acttggctat gggaccagag ttattaaaat
     7261 caataagtga aaatacaaca atacctttag acatacactt agccacagaa actccagata
     7321 aatatattga tatgatgtct tatataaagc caaaatatat ttcttttcat gtagaatcaa
     7381 gtacaaatgt aaaagctgat atacaaaagt taagaaatta tggtataggg ccagtgttag
     7441 caataagccc tcaaacaagt gtggataaaa tagaagaata tataagttta gttgagggta
     7501 tcttagtaat gacagtaaat ccagggtttg caggtcaaaa gtttaatctt tctgtattgg
     7561 ataagttgga taaacttaca gagatactaa aagattatga taatcctcca tttatagagg
     7621 ttgatgggaa tataaataag gatactatta aacttatgaa tggtaaaaaa gtagatatat
     7681 atgttgttgg tacttcagct ttatttaatg ataagcctcc aatttcatat aaagataaaa
     7741 tagaagaact aaaagaaagt ataaagtaac catgtaataa aattataata tgtttctgtt
     7801 taatagtaaa aatttaggtg gaaacaagaa attttataat atttaataaa aattttggtt
     7861 gagtaaggag aattttttat gggagaccta tataaactac aaaatggtac tgatattaga
     7921 ggaatagcgt atgaaaatga ttctaaagaa gttaacctaa ctgtagaaga agtaaaaaaa
     7981 atagctaaag cgtttcatat ttggttaaaa gaaaagacta agaaagataa agtaactgtt
     8041 gccataggaa ctgattctag gataacagga agccaattta gaagtactgt tattgaaact
     8101 ttaactaatg acgattgtaa tgtaattgat tgtgagattg ccacaactcc agctatgttt
     8161 atgacaacta ttatggatgg atacaattct gatggggcga ttatgattac agcaagtcac
     8221 ttaccttatt actataatgg tttaaagttt ttcacagaaa gtggaggttt agaaaaaact
     8281 gatataaaag agatgttgga tatagctgtt aaaaatgata gtgtagacta tgaggaagta
     8341 aataaaaaag gtgaagttat agtaaaaaat ttaatagaag attattctaa tttattgata
     8401 gataaaatta gaaaaggtgt aaattcaagt aaaaattatg aaaagccttt ttctgggctt
     8461 aagatattgg ttgatgcagg aaatggggct ggtggattct ttgctgaaaa agttttacac
     8521 atactgggag cagatacgac aggtagtcag tttttgaacc cagatggtat gttcccaaat
     8581 catataccta atcccgaaaa caaagaagca atggaaagca tatgtaaagc tgtgttggat
     8641 aataagagcg atctaggaat aatctttgat acagatgtag acagagctgc tattgtaggt
     8701 aaaaatggca aaccaataaa taaaaatgct cttatagctg ttatatcatc aatagtatta
     8761 gaagaacatc caaaaacagc tatagtaaca gattcaatta cttctgaagg acttgctaaa
     8821 tttataaatg aattacaagg aagacatcat agatttaaaa gaggatataa aaatgtaata
     8881 aatgaagcta taagattgaa tagtgaaggt gaagagtgcc atttagctat agaaacgtct
     8941 ggacatgctg ctttaaaaga aaattatttc ttagatgatg gggcatattt aatagctaaa
     9001 attttgataa aagtagcaaa gctatccttg gaaggaaaga ctatagaaga attgatagaa
     9061 aaccttgaag aagctcaaga agagaaagaa gttagaatag gcattaataa agaagatttt
     9121 agaccatatg cagaggatat attaaaagat ttagattctc atgttaagag tattgatgga
     9181 tggtctgtag caccaaataa ttttgaaggc ataagagtta attgtgatga atcaaatgga
     9241 gatggatggt ttttacttag aatatcacta catgaaccat tattagcttt aaatattgaa
     9301 tcaaataaaa ttggtggagc agaacaaatt tattctaagt taaaactttt cttagaaaaa
     9361 tatgatttaa aaggtcttta gggtaaatag aaagaatata tttatattga agaataaatg
     9421 taaatttgta cctaagatta caaatattac aaaattgtaa tcttaggtaa cagagatgta
     9481 actgattatg gaaacactat gtgatattat agatacagag agatgaaata tatgatgaat
     9541 tatagagaaa tataatttaa aatgtattaa tatcacacca aaaaggtata atcaaaaaat
     9601 atgtaaatat aaaccccaac atttagaaaa agacctctaa ggaggttttt ttcttgttta
     9661 aataacttaa aatatatttt tatattaata tatcaattaa ctcttctaaa agtaagcatt
     9721 accttaaata aatcagcatc tataattatt tccatgtgtg cattttctaa ttcaattata
     9781 ttttgagcaa ttgataaacc aagaccagag ccatctgttt ttctagatat atcacccctt
     9841 ctaaatcttt ctattaactc ttctggcttt agatttagtt tatcatttga aatattttta
     9901 aacgttaata ttatattttc ttcctttata aacatatcta tgtagaccct agtgttaggc
     9961 atagagtatt ttagtatatt gcaaattaga ttctcaaaaa ctctccaagt ttttttacca
    10021 tctatcatgg taaaaacagc atattcaggt gtttctatta taaaatctaa actgctattt
    10081 tgaattttgt cttcaaactc tacaatactt tgaattaaaa gttctcttat atcggttttt
    10141 gttatattaa attctacatc tccactactt agcttagatg cttcaaatat gtcatctatt
    10201 aataatttta atctttgtga ttttttatct aaaatattta tatagtcatt tatagtctct
    10261 ctgtcaaagt cattattttt taacatatca acatagctta atatagatgt aagtggagtt
    10321 tttaagtcat gagatacgtt tgtgataagc tctgccttca tcctttcatt ttttatatta
    10381 gcatctacag cagtttcaag accgcctgtt atattattta tacttttggc taaagtagat
    10441 atttcatcat ctcctataac ttttaattta tactttaaat tgccattttc tatatttttt
    10501 atattttttg atatgttatt tatgtaatta aacttaacag ataaaaagtt gtatatataa
    10561 aaatgaaaaa ctgtgtttac aagtgtaaat aaaattacta tagctattgc ctcagcataa
    10621 tatatataca taaagaatat caaaacaaga tattggataa tagcttgtac aactatagat
    10681 attaaaaata ctatagctaa ttttttattt atagtttttt tattatacat actaagtaag
    10741 tttgaaaaga atacatatgt tatggacata tcttttagat tatagttatt atatttaata
    10801 ttttcatata ttatatagac tatagatata attataaaat tgtagattat taaattagtg
    10861 ttgtaaaaca ttttattact tgtaaatgca tgaaacctta aggttaatag tatcaaagtt
    10921 aatataagtg taagttctat ttttacctta gaaaaaaggc ttataacatt ctctaagaat
    10981 ttgactttag tctgtttatt ttttttatac aatgtaaaac atagtatagt caataaaaaa
    11041 cttgataata taatacctat gcagacaaac tctaattcta cttttgacaa atgtacagga
    11101 gtaccgaaaa aataaaaata agggagagca aactctttat aataacaatt aatattataa
    11161 gaaaagttat tattcaaatc ataaactgct tcaaataata tagaaactaa tagaaacagt
    11221 aataataata aaataaattt tgctttagaa tcattaataa ttaagttttt caattttgta
    11281 accaatgccc cacaccacct ttaaatattt tggttctttt ggattaattt caatcttttc
    11341 tctaattctt ctaatatgaa cagcaatagt tctctcacaa ctataagcat cctcattcca
    11401 gacattttca taaatctcat gagaagagaa aattttacct tttcgtgaca taagaagtgt
    11461 aagtatttta tattcaagtg gtgtcatttt aatttcctca ccatctaaag aaactatttt
    11521 tgtatctgta tttagctcta ggccaccact ttttagaata taattagtat catttgagtt
    11581 atttgtatta ctaaaatcac ctaaatttat ataccttcta agttgagatt ttactcgagc
    11641 agtaagttct agtggattaa atggtttagt tatataatca tcagcaccca tattaagacc
    11701 tataattttg tccatatctt ctgattttgc agataagaga attattggta tattcctttt
    11761 ttctcttatt ttaagtgtag ttttaagccc atctaaattg ggcatcatta catccattat
    11821 tattaactta atatcatttt cgattagtat gtccaatgct tcaagtccat catatgcctt
    11881 taaaacatta aagttatcag gtctcaaata gaactctata gcatcaacta tctctctatc
    11941 atcatctaca accaatatat tttgattcaa cttattaacc cccttgaaat tttattttta
    12001 accaattttt attttatacc aaaaagaggt attagaaaac agtaagcccg ttcattatga
    12061 aataaaaact agtactttta atatattgtc aatgcatata gtaaatttaa aagtatagac
    12121 gcccatatta atctgaaggt aaaagtttat gaaaatatct agggtaatct atcacacttc
    12181 ttatgttatt ttggtttatt aattttttag gtttaaacat atattaacaa atataaataa
    12241 caaatgagtt tcataattat taagaattta taacaaatat ttattttaat gtagtttaat
    12301 ataaacaggt agtttaatgt aggtatgtat aaagcattta ataaggctta taggttttaa
    12361 tgatgatatc tttatatatt ttaagagatg atgaaattag atatgggtaa tagttgtatg
    12421 agaaaaagta gtatagcaca aaaagtgcta tatcacaaaa tctcaaataa tttccttttt
    12481 ataacttaaa ttaaaagaat aaatatttct tataaattag gtgtatgaag tatagcagga
    12541 acatctttat tatttaataa cttatcaaat gatttatggt cagacttata gccaatacct
    12601 tctctatatt ctaattcatc aacaattttg tattgttgac aggcattttt aaccttttca
    12661 tagtcttcag tagaatgagc tttataaact atcttattat taaaagttat tttatcagca
    12721 aatttaggtt ttacaaaata tttagcatct tttattttac cagcattata taaattttgg
    12781 ataacagaac cattttttaa atgttgtaaa tggtcatcta acttataagt atgtgctata
    12841 tgagttacat ttttaaattt ttcttcaaat gtaagagcaa ttttttccat gtaattgaag
    12901 tcagtattac catttgtatt tgtttctggt aataatatta tattttccct tattacacca
    12961 aggctattaa gagaagctaa aaattctcta tttctatatt ctgatttttg tatatttgtt
    13021 aggttttcat attttttata tttatcaaag acggatatac cacatccagt agatactaaa
    13081 accacaaata catgattttt tcctctttct tttatagcat taacaatagc actcccagcc
    13141 cacaacactt catcatcttg atgctgaaca tagaagacaa cataatcttt aaatttttta
    13201 tgactataat tcacatagct actaaaagcg gttaaaatca aacataaaac tagaataata
    13261 gatagaattt tatatttatt tatagtaaat tttttattct taaatgtcat ttaatcatct
    13321 cctgaaaagt tgtcttagtt atattatcaa acaaagtact aaaaattatt tcttaaatgc
    13381 tgaaaaatat agagtagatt aatggaataa aattttttta ttagtttaaa ataaagaaaa
    13441 catttatgta taagactaat caaaatatta atgattgata ggaattgaga tttaaaggga
    13501 ttgtacattt attcgggatt cattttaata gaattttact ttagtactta gaataaaagt
    13561 aataactttt taaatttaaa gagtacacat atatatttgt gtactccttg atgatatgat
    13621 tgcttattta ctacaaaaac agagtctttc taaacctaaa atatttgatg caccagctat
    13681 cgtagttcca taatagtaaa ctggtttgtt aagtgataga aaatttataa ttgagttatt
    13741 acataatgta cttcctgtgc aaatcactaa atcagcccaa gatattacat cttcataatc
    13801 tcgtatacca tcttcaatct taacattata ttgaatagta tccacaaatt caggatttaa
    13861 atctaatact cttgtttcga aaaagtcctt aatattatca attatggctg gttgatatcc
    13921 tataattgct acttttggat taccaaattc catttttata aactcaggga atttttttgc
    13981 acatacctct ggctcgttat ttttacaatg aatggttcta tccgtcttgc ctaagtattt
    14041 cataactgca tttaatgatg ctataaaaag acttctatca tgaggattgt catgtaaatc
    14101 taatgataat atgtctttta aagaaccttc aaatgtagat ggagtagaag taaatgcttg
    14161 tcctttagct cctttaaagt cagcttcaag cattatttct ttaccaacta taattggaaa
    14221 atctttacgc ttagtatttc caattgcttc ttttgaagat agagatttgg acacaatact
    14281 tatcatatcc atatttaaat tatatttatc gacttgtact aatagataat ctctcaaaat
    14341 atcaaatata ttcatagaaa aaagattctc ctttattttt tatttcttca tttaaatcaa
    14401 aaatatgatt tatttttcca ttgttcatta ttcctatctt atgagcaaaa aacattgctt
    14461 cagaaatatc atgagtaaca tgaatcactg ttggtttgta ttttatgtag acatccttca
    14521 aaattttgct tatatgtttt tttgtaatat aatccaatga actcataggt tcatctaaaa
    14581 gtaatatatc aggttcagct attaaggcac gtgcaaaagc aactcgttgc ttttcgcctc
    14641 cacttaaatt tttaggatac ctatttttta tatcttctat ctgcattaat ttagacaagt
    14701 ggttagcctt aagaatctgt tcatctatag gtatttttct taatttaagt ggaaacctta
    14761 tattatcttc aacactcata tttggaaata attcaaaatt ttgatataca aatcctatat
    14821 ttctattttc tggaggtaag tttgatatta aattttcttt gtatgataca tttcctttag
    14881 cagatggata tcttcctgct aatgtttcta ggaatagagt tttacctgac ccactagctc
    14941 ctaataaaac aaagtattca tgattattaa tatttaaact attttcttgt aatttaaaat
    15001 taggtaaatc aagagataaa ttttttattt ttaacatatt aattcttatc aacctctcta
    15061 ttaaaaaata tctcaaaaag catcaagcat gtaagtgaga taaatatcaa aattacagct
    15121 attccgattg caatgtctat atcaccagta gacatattta aatatataga tgtaggaata
    15181 atttcagttt tcatacgtgt agaacctgct atcatagcta ctgcaccaaa ttcaccaagt
    15241 gctcttgacc aagtcattac agttgcagat atgattccag tttttagatt tggaagaatt
    15301 ataaatctaa atgcttccca actattacat ccaagggtac gtgcaacaaa tatcatcttt
    15361 tcattacttt catttaatga agtgtgaagt attttaatag taagtggaag atttacaaat
    15421 atttgtgcta aaactatacc ttgctttgta aatataaaat caagcttaaa aatcttataa
    15481 atggaatctc caatccccat tcttccaaac aaaagtaaaa gagcaattcc tgatactaag
    15541 tgtggaagag acatagggag atttattatc tgtataatca gttttttaaa tggtaattta
    15601 gtaatatgta aaaaatatgc tactggaata gctaataaaa ggcatactat agtagatatt
    15661 aaagatgttt taatactaag tgttattgca tactgtactt ccactgattt taagcatata
    15721 ggaacataac ttatcccttt aatgattaac ataagaagtg gtgatacaat aaacaaaaag
    15781 actatagcaa aaaatccagt aagtagagta gtaaaaaatt tatttttcaa gtttaatcac
    15841 tacttaacag gttcaaaacc atatttttta aatatctgtt tagcttcgtc tgactctata
    15901 taatttataa atttattagc taaatctttt ttatcactat agtttacgat tcctgctgat
    15961 ataagttggt ctatattttt atcttgggca atttctataa cttctacatc ttcattacca
    16021 aagaccgaat cttttgtggc tattgtagca tcagctttac ttgatgttaa ctgtacaatc
    16081 atttcattta cagttgcagc tgtagagaca acattatcat ttatagattt taaattattt
    16141 ttttcaagta ttttttgtgt agtcttacct atagcattag actctttgtc tcccaaaata
    16201 agtttaactc catctttatt taagtcttcc aatttttgaa tattagctgg atttccttta
    16261 ggtacaacta ttgcaggtgt atgatgtgca accgttttat gttcacctac aagttctttt
    16321 tcaaaggcct ttgaataaat tggttcagaa ccaacaataa atacgtctcc tttgtgactt
    16381 gtctcaattt gagctattag ctgtgcagaa cctgcatagc tatattcaac tttgacatta
    16441 ttttctttct caaatttttt tgctatttca tccattggtt tctttaaacc tgcccctgaa
    16501 tagacaaaaa gagtctcttt ttcttttgaa tcatcagctg ttgtcacttt agtattagat
    16561 tcatcattag ctttgttttc tttagaatta catgcagtaa tacttaatga aataatcata
    16621 gctaaagcta gtactgaaag ttttttaaac ataagatatt cccccttagt aaattagtgt
    16681 aaattctttt ttagtatatc atactaagaa aacgatgtct aagtttttgt tatgttttat
    16741 aatgttttgt tatgttttgt tatgtatagt taagaaaaaa tctatttata
//
LOCUS       DAMKNB010000075        16684 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.079, whole genome shotgun sequence.
ACCESSION   DAMKNB010000075 DAMKNB010000000
VERSION     DAMKNB010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 16684)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16684)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16684
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.079"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            complement(14..1090)
                     /locus_tag="PC494_002802"
     CDS             complement(14..1090)
                     /locus_tag="PC494_002802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--glyoxylate aminotransferase family
                     protein"
                     /protein_id="HDF3913292.1"
                     /translation="MSKKLFIPGPIDVKEEVLQKMATPMIGHRGKDASMLQKSISEKM
                     QKLFYTNNTILLSTSSGTGLMEGSIRSCTSKKAAVFSCGSFGDRWYKMAVANNVPADI
                     FKVELGEATTPEMVDKVLSTGEYDLITVTHNETSTGIRNPIEEIGEVVKKYEDVIYCV
                     DTVSSAGGIKVEVDKIGIDICITSVQKALGLPPGMSICTFSQKAIDRAKQVPFRGVYL
                     DLLAMYEYLIKKNYQYPSTPSLSHMFALDFQLDNILDEGLDNRFNRHEDMANLVRNWA
                     KKHFQIFTNENHLSNTLTVIENTQGISVSNLNSKLQERGFQIANGYGDLKEKTFRISH
                     MGDYTVEDVQELLDNIDDILGFNK"
     gene            complement(1463..1978)
                     /locus_tag="PC494_002803"
     CDS             complement(1463..1978)
                     /locus_tag="PC494_002803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PaaI family thioesterase"
                     /protein_id="HDF3913293.1"
                     /translation="MDFLAKYKVLKKQNSSKSCLVCGTQNELGLKADFYELENGELVS
                     ICNTKDWHQSYPGRVHGGMSAAILDETIGRAVSINDDQIWGVTVSLELKYKKPVPTDA
                     TIKVVGRITKENRKLFEGTGEIILPNGDIAVTATGKYMKMPIGQIAEGDFSNEEWFFE
                     ESKEKVEYIEL"
     gene            complement(2341..3411)
                     /gene="leuB"
                     /locus_tag="PC494_002804"
     CDS             complement(2341..3411)
                     /gene="leuB"
                     /locus_tag="PC494_002804"
                     /EC_number="1.1.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydrogenase"
                     /protein_id="HDF3913294.1"
                     /translation="MNCNIAVIKGDGVGPEIIDEGIKVLNKICCKFNHRFDCEYVLAG
                     GCAIDETGEPLPNKTVETCRKNEAVLLGAVGGPKWDKCKGDKRPESGLLKLRESLGLF
                     ANLRPATMYESIKEASPLRTDIVEKGIDFVVVRELTGGIYFGERGRKIIDGIENAYDV
                     EIYNENEIRRIGKRAFEIARNRNKKLISVDKANVLESSRLWRSIMEDLAKEFEDVELS
                     HMYVDNAAMQVVKDPSQFDVIVTNNIFGDIISDEASMITGSIGMLPSASLREDSFGMY
                     EPIHGSAPDIAGKDIVNPIATILSVSMMLRHSFNLEEEAKCIEDAVQSVLNKGYRTID
                     IYNGVGNVVGTREMGELIVNEI"
     gene            complement(3418..3909)
                     /gene="leuD"
                     /locus_tag="PC494_002805"
     CDS             complement(3418..3909)
                     /gene="leuD"
                     /locus_tag="PC494_002805"
                     /EC_number="4.2.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase small subunit"
                     /protein_id="HDF3913295.1"
                     /translation="MIANGSVFKFGDNIDTDVIIPARYLNIADYKELATHCMEDIDDK
                     FISKVKKGDIIVATKNFGCGSSREHAPIVIKESGVSCVIASTFARIFFRNSINIGLPI
                     LECEEAANNIDEGDNIEVDFSTGVIKNITKGKEYKAEPFPEFMQNIILNEGLINSIKA
                     NRG"
     gene            complement(3924..5201)
                     /gene="leuC"
                     /locus_tag="PC494_002806"
     CDS             complement(3924..5201)
                     /gene="leuC"
                     /locus_tag="PC494_002806"
                     /EC_number="4.2.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase large subunit"
                     /protein_id="HDF3913296.1"
                     /translation="MGMTMTQKILAKHAKLNEVKKGQLIEADLDVVLGNDITSPVAIR
                     EFEKLGIEDVYDKTKVVMVLDHFTPNKDIKSAEQCKFTRSFAKSKGVVNFFDVGDMGI
                     EHVLLPEKGIVTAGDVIIGADSHTCTYGALGAFSTGVGSTDMGAGMATGKCWFKVPGA
                     IKFVLKNKPNKWISGKDIILHIIGEIGVDGALYKSMEFCGDGVEYLSMDDRFTICNMA
                     IEAGAKNGIFPVDDKTMEYINSHKCSTMTKDVNIYEADEDAVYDEVYEIDLAELKETV
                     AFPHLPENTRTVDEIDKDIKIDQVVIGSCTNGRISDLEVVAEIMKGKKVADGVRVMIF
                     PGTQKVYLEAIEKGYITTFIEAGAAVSTPTCGPCLGGHMGILAAGEKSISTTNRNFVG
                     RMGHVDSEVYLASPAVAAASAITGKISKPSEII"
     gene            complement(5158..6900)
                     /gene="leuA"
                     /locus_tag="PC494_002807"
     CDS             complement(5158..6900)
                     /gene="leuA"
                     /locus_tag="PC494_002807"
                     /EC_number="2.3.3.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-isopropylmalate synthase"
                     /protein_id="HDF3913297.1"
                     /translation="MKCGKYKKYDKMQIVNRKWPDNEIFKAPIWCSVDLRDGNQSLPT
                     PMSVNEKVRMFKMLIDTGFKEIEVGFPSASNTEYTFLRKLIDENMIPDDVTIQVLTQS
                     RAHLIEKTFESIRGCKKAIIHLYNSTSVLQRDVVFNMSKQEIIDIAVEGAKLFNEEVK
                     KYPETEFTFEYSPESFTGTEMDYALEICEAVIDVWKPTPQKKVIINLPSTVEMATPNV
                     YADQIEWFCKNISCRDSIILSLHTHNDRGTCTAASELGLLAGADRLEGTLFGNGERTG
                     NMDIVNVGLNLYTQGIDPELDFSNIDKIIGIYEDCTKLMVHDRHPYAGNLVHCAFSGS
                     HQDAIRKGMIAMKNRDNDYWEVPYLPIDPHDIGREYKEIIRINSQSGKGGAVYIMETD
                     YGFMIPKNMHSDFGNVVKMESDRIGEELSSEAIFNLFKKEYIEVESPYKVKKYKIKSM
                     DELNYENDDSNDTNMIEMTARISYMGNEQRIVGIGNGPVDSFNNALKQCGMKDYKFRY
                     YWEHALEEGSHSRGVAYVGIEHNNEVYFGVSISENINTAAINALMNAINKSYIEEEIK
                     NGDDYDAENISQTC"
     misc_binding    complement(7024..7270)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(7418..7864)
                     /locus_tag="PC494_002808"
     CDS             complement(7418..7864)
                     /locus_tag="PC494_002808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3913298.1"
                     /translation="MSKNKFIYMNYYDNGYFKKGMTIYMVLALIILATIFIYSTTILY
                     ILCIITAVFLFKQGRDFSNKYEGKVYITLDNHSILINNQCIFSIKSKQSQKFNYKIIE
                     KIEVVKNILNIYTDESNYKIRLRALSLEDEKKLLNIIDEKMKKFKA"
     gene            complement(7885..8604)
                     /locus_tag="PC494_002809"
     CDS             complement(7885..8604)
                     /locus_tag="PC494_002809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase"
                     /protein_id="HDF3913299.1"
                     /translation="MKKSIMDVHCHTLISGHAHSTFKENVEEASKKNIKYLGISDHGP
                     NMPGGPHPFYFYNLHLLPREVQGVKILRGIEGNIMDYNGNLDVQEDMLKHLDYIIASL
                     HRPCIASGTKEKNTNAILKVMDKPKVKIIGHPDDSRYPLDYEPIVKKAKDKNILLEIN
                     NSSLSSNSHRTGTWENVSHMLTLCKTYGARVILGTDSHICYSIGEFENAEKVLEAVDF
                     PDELVINYHEDEIIEFFDINF"
     gene            complement(8722..9996)
                     /locus_tag="PC494_002810"
     CDS             complement(8722..9996)
                     /locus_tag="PC494_002810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HDF3913300.1"
                     /translation="MFIMENDLTMQELLDQQEQVFSKVKVGELTTGKITAVRNDEVQL
                     GLDYGFDGIIPISELNIEKNQYIEDIYHIGDEITAVITKVSQKDGTITLSKLQLDKRN
                     DFAKLQKAYDEHRIITVNVEKNIDKGVFANYNTYTFFIPISQLDTKFITDTSKFVGLN
                     LEVYIKELDVRKNRLVASHRDVLQERINKEREERRAQIKAEKEAERARIKQEREEEKA
                     RIKAAKEDLFNSLEVGQKRDGKVTKIMPYGAFVDIGGIEGLAHINNLAWTRVESVEDV
                     VSEGQEVEVYVLDVNKETKKIALALKDINNDPWDLIAKEVQIDDVVNAKVLRIIEKGA
                     FVQIKEGVDAYLPISELSDTRVAKVTNVVNIGDEVKVKILDFKPKTKRMLVSIKEATR
                     EPEEDITEYLEVEESLGSIGELFKDKFKDLEV"
     gene            complement(10196..11563)
                     /locus_tag="PC494_002811"
     CDS             complement(10196..11563)
                     /locus_tag="PC494_002811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HDF3913301.1"
                     /translation="MENSNTNLGSESVGKLLFKLATPAIIAQIVNVLYNIVDRIFIGR
                     MENGEVAMAGVGVAFPIIIIITACSYLIGMGGGPLAAIKMGEQNNDEAEKIMSNSFSV
                     LVILAILLTIGFKIGKEPLLWMFGASESTIGYSMDYLNIYLIGTVFVQISMGMNTFIN
                     TQGFATTGMMTVAIGALINIILDPIFIFGFNMGVKGAALATIIAQGVSAIWVLMFLFG
                     KKSILKIKKKYMIPKASIILPVLGLGISPFIMQSTESLVLIALNSKLQMYGGDLAVGS
                     MAIMSSIMQILMLPNMGVTQGAQPIISYNYGSGQLDRVKKTFKLCLLSCFTYSTILWL
                     LLMIFPAFFVSIFNKNPQLLSMTSWSIKIYFAGAFMFGIQIACQQTFLALGKATISLV
                     LALLRKIVLLIPLIFILPTFFNEKLFAVILAEPVADITAATITAISFFIFYKCFLSKP
                     KAIKE"
     gene            complement(11813..12277)
                     /locus_tag="PC494_002812"
     CDS             complement(11813..12277)
                     /locus_tag="PC494_002812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="small multi-drug export protein"
                     /protein_id="HDF3913302.1"
                     /translation="MSLRIGGNSLGYLHILILSMVPVTELRGAIPIGIAMGLNPIWVY
                     VFSVIGSTLVSIPLILTFRHVLQFLRGKKLFKGIADVIDRKINSRMKKLKSVSIIGII
                     LFVGIPLPTTGTWTASAIASILKMRIKDAFMGVFLGNLLSGVIVSALSLHII"
     gene            complement(12282..12911)
                     /locus_tag="PC494_002813"
     CDS             complement(12282..12911)
                     /locus_tag="PC494_002813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IB family hydrolase"
                     /protein_id="HDF3913303.1"
                     /translation="MKKSVLLLDVDYTVINTDSMIDFFIYSLKNKTFKTIIKLPYIIF
                     ILFMYLIRMIPLKKAKEAIFYPIVDFSEEDLKKFFDDCIMKKINESMKKVIYKNKEED
                     NVIIMITASPYAYMKYFKYYGLADEVIGTEFFYENSRYKNQFIGENCKGIEKLKRIKA
                     VLGKLGIEIDYENSYAYSDSKSDLPMLSLTKNAFLVSKKDGEVIEQINS"
     gene            complement(12945..13832)
                     /locus_tag="PC494_002814"
     CDS             complement(12945..13832)
                     /locus_tag="PC494_002814"
                     /EC_number="2.4.2.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="decaprenyl-phosphate phosphoribosyltransferase"
                     /protein_id="HDF3913304.1"
                     /translation="MKQTNTSIRLLTKISDYIKLMRIKQYIKNFFVFSAIIFSNNILN
                     INLFLNTFIAFVCFCLMSSSVYALNDAIDMDKDKKHPKKCNRPVASGRISKKSANILF
                     VVLALISVCLSTVVSFNLSIILSLYLINNILYSLKLKNIILLDVFSISLGFILRVYAG
                     CVAISVSLSNWIILCTFFLSLYLALGKRKKEIETLRDDAVEHRKILEDYDIENLNQMM
                     IVILSSTIVCYALYSTSNPEKPHMIFTTIFVVYGVLRYNYIINTTNENNPTDIVLKDN
                     ALKINVILWIITCLIILIF"
     gene            complement(13861..15099)
                     /locus_tag="PC494_002815"
     CDS             complement(13861..15099)
                     /locus_tag="PC494_002815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3913305.1"
                     /translation="MDGDILMSKILKYKNEMFLFILVVITYLIITKIFFSKTTIFYDL
                     NNTYDVLLDTDTGVLFNLNVFAISQDNSKHILFSAIISIFAYPIYLFCTSIANPGTTD
                     FNSAYGFGLICLQIITSAMSITLVFNHIKKIKMQRLTLILLTMIMIFSFPQLFMTLNV
                     ERFIYSQFSLIFFIVIANKMKGKNSYLVELAAIPLFGITISNIYLYFFNMIFEFKLKI
                     GKMLKHLITFILMAYICVVSTKSYESFMNLGNVIQYDTKFISGEPILEKIAMIIERLL
                     YSVFYFPGASIKKGLFLQNGEVATIPVILTLLALCFCVLSVIENSEKRVPKLCMGIII
                     FNLTLHGIVGYNLVNSSIMAINFSFAVIILLAYFTKALRKNEKNMYNIFLSLLLVTIV
                     ISNVNGFIEILNIGIKSYPV"
     gene            complement(15483..16625)
                     /locus_tag="PC494_002816"
     CDS             complement(15483..16625)
                     /locus_tag="PC494_002816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HDF3913306.1"
                     /translation="MRYVEYGKTGKMVSVVGYGGLRFDLEKSNQENADLVKYAYEKGI
                     NYFDTAPGYCDDRSEDIFGLAFRQMIKEGKTDFYVSTKEKPKACDTSEKAIEAVKKSI
                     ERLGVSKINFYHVWNIRKMEHYELAMRPGGQYEGLLKCKEEGLIDHIVFSSHQPGDEV
                     IDILSENKFEGVTMGINILNFPYRLKGAKYAVDNGYGVVAMNPLSGGTIPKYNKELSF
                     LSKDGESTIESALRFNIGISQISISLIGFNKKQDIDDACKIADENRIYSDEDIHDIET
                     RLNKNMNEICTGCGYCKVCPKGINTPAYMLFYNEKQMFKKSDEEMTKLVYGLGHWNYT
                     MNSKAKAKECISCGKCEVECTQHLPIIDRLKEIKKWEEDGANSVKV"
BASE COUNT         5406 a         3043 c         1736 g         6499 t
ORIGIN      
        1 tatttttaca atattattta ttaaaaccta atatatcatc aatattatct aataattctt
       61 gtacatcttc gacagtatag tcacccatat gtgaaattct aaaagttttt tcttttaaat
      121 ctccatagcc atttgctatt tggaatcctc gttcttgtaa ttttgaattt aaatttgata
      181 cactaatacc ttgagtattt tctataacag taagtgtatt ggataagtga ttttcattgg
      241 taaaaatttg gaagtgtttt ttagcccagt ttctaactaa gtttgccatg tcttcatgtc
      301 tgttgaatct gttatctagg ccttcatcta atatattatc taattggaaa tctaaagcga
      361 acatgtgaga aagagatggt gttgaagggt attggtagtt tttcttgatt aagtattcat
      421 acattgctaa caaatcaaga tatactcctc taaaaggtac ttgcttagct ctatcgattg
      481 ctttttgaga aaatgtgcaa atagacattc ctggtggtaa tcccagtgct ttttgtactg
      541 atgttataca aatatctatt ccaatcttat caacctcgac ttttattcca ccggctgaac
      601 ttacagtatc tacacagtag attacatctt catacttttt aacaacttct ccaatttctt
      661 ctattggatt tcttattcca gttgaagttt cattgtgagt tacagttatt aaatcgtatt
      721 ctccggtaga aagcacctta tcaaccattt ctggcgttgt tgcctctcct aattcaactt
      781 taaatatatc cgctgggaca ttattagcca ctgccatttt gtaccatcta tcaccaaagg
      841 atccacagga aaatactgct gcctttttgg atgtacagga acgaatggag ccttccatta
      901 aaccagttcc ggatgacgtg gataaaagta tcgtgttgtt tgtatagaat agtttttgca
      961 tcttttcact tatactcttt tggagcatag atgcatcttt tcctctatgt cctatcattg
     1021 gtgtagccat cttttgcaag acttcttctt taacatcaat aggaccagga ataaataatt
     1081 tcttactcat tataattccc ccctttttag tttgtaatat ggatagcgtt tttactgtcc
     1141 ttatttttaa taactataat atcaagctga attaactatg tcaacataaa atttattttt
     1201 tatatataat ttattttata tattttatga aaacattcat tttctacctt ttcataagtc
     1261 tgaattttct gaattattct ctcaaaaaaa atatactttt tatctatata aattaatttt
     1321 tttagtatgt aaatttgacg ctattacgat aaatcttttt agtataacta atttattttt
     1381 atcttgtatt tttattgtat ttttgaattt tattttttct aaatataaaa tttatgtttt
     1441 aaaatgtaaa atttttattt aatcaaagtt caatatattc cactttttct ttcgattctt
     1501 caaaaaacca ttcttcatta gaaaaatcac cttctgcaat ttgtccaata ggcattttca
     1561 tatactttcc agttgctgtc actgctatat ctccatttgg tagaattatt tctcctgtac
     1621 cttcaaataa ttttctgttt tctttagtta ttcttccaac aacttttata gtagcatctg
     1681 ttggtactgg tttcttatat ttcaactcta aagatactgt tactccccat atttggtcat
     1741 catttatact tacagctctt ccaatagtct catccaatat tgcagcagac atacctccat
     1801 gaactctccc aggataactt tgatgccaat cctttgtatt acaaattgat acaagctctc
     1861 cattttcaag ttcataaaaa tctgctttaa gtcctagctc attttgtgtt ccacaaacta
     1921 aacaagattt actactattt tgcttcttca aaactttata ctttgccaaa aaatccatct
     1981 cctaaccgac attagtagtc gcttaatatt aaataattct aaaatatatt atataatatt
     2041 aataaaatcc ctgcaaactt ctaataataa aaataggcta cttcaatatg ataagtttaa
     2101 tttaaagtat tattttccaa aaaataactt tatcaaaata gaaactcaaa gtagatataa
     2161 gcctcttttt cgttattaaa atagtaaaaa tatattttac ttaatataaa aaagagtgtc
     2221 tcattaacta ataaagttta ttttgagaca cccctcataa aacaaattat actacaatag
     2281 atttttacta attctacaag ttatatattc aaattatatt attcaaatta aactataatt
     2341 ctaaatttca tttactatta attcgcccat ttcccttgtt cctacaacat ttcccacacc
     2401 attatagata tcaatagttc tataaccttt attgagtaca ctttgtacag catcttcaat
     2461 acacttagct tcttcttcta agttaaaact atgtcttaac atcatgctta cagatagaat
     2521 agtcgcaatt ggatttacaa tatcttttcc agctatatca ggtgcacttc catgtattgg
     2581 ttcatacata ccaaaactat cttctctaag tgatgctgat ggtaacatac ctatagaacc
     2641 cgtaatcata gatgcttcat cagatattat atctccaaat atattattag tcactattac
     2701 atcaaattgg ctagggtctt ttacaacttg catagcagca ttatcaacat acatatgtga
     2761 cagttctaca tcttcaaact ctttagctaa gtcttccatt atacttctcc aaagtcttga
     2821 actctcaagc acatttgcct tatctacact tataagtttt ttatttctat ttctggctat
     2881 ttcaaaagct ctcttaccaa ttcttcttat ttcattttcg ttatatattt ctacatcata
     2941 agcattttcg ataccatcaa tgatttttct tccacgttct ccaaaataaa tgccccctgt
     3001 taattccctt acaacaacaa aatcaatgcc tttctcaact atatccgttc taagtggtga
     3061 agcttctttt atactttcat acattgtagc tggtcttaaa tttgcaaata aacccaatga
     3121 ctctcttaat tttaaaagac cagactctgg tcttttatct cccttacatt tatcccactt
     3181 tggtcctcca acagcaccaa gcaatacagc ttcgtttttt cgacaagttt caacagtttt
     3241 attaggtaga ggttctccag tttcatcaat cgcgcatcct ccagctaata catattcaca
     3301 atcgaatcta tgattaaatt tacaacaaat tttatttaga acctttatac cttcatctat
     3361 aatttccggt ccaacaccat caccttttat gactgctata ttacaattca tacttcacta
     3421 ccccctattt gcttttattg agttaattaa gccttcattt aatataatat tttgcataaa
     3481 ctcaggaaat ggttctgctt tatattcttt tccttttgtt atatttttta tcacacctgt
     3541 agaaaaatct acttctatat tatccccttc atctatgtta ttggcagctt cttcacattc
     3601 aagtatagga agccctatat ttatagagtt tctaaaaaat attctagcaa aagtagaagc
     3661 aatcacacag gatactccac tttcttttat tacaattggt gcatgttctc ttgatgaacc
     3721 acaaccaaag tttttagttg caactataat atctcctttt tttaccttag aaataaattt
     3781 atcatcaata tcctccatac aatgcgttgc tagttcttta taatcagcta tatttaaata
     3841 tctagctggt attattacat ctgtatctat attgtcaccg aatttaaaaa cacttccatt
     3901 ggcaatcata aattttacct cccttaaatt atttctgatg gttttgatat ttttccagtt
     3961 atagctgatg ctgctgctac agctgggctt gcaagataca cctctgaatc aacatgcccc
     4021 attcttccta cgaaattcct atttgttgtt gaaatggatt tttctcctgc tgcaagtata
     4081 cccatatgtc cccctagaca tggaccacaa gttggtgtag aaactgctgc tcctgcctct
     4141 ataaaagtgg taatataccc tttttctata gcttcaagat atactttttg agttccagga
     4201 aatatcataa ctctaactcc atctgctact tttttgcctt tcattatctc agctactact
     4261 tcaaggtctg atattcttcc atttgtacaa gagcctatta caacttggtc tatctttata
     4321 tccttatcta tctcatctac tgttctagta ttttcaggaa gatgaggaaa ggctactgtt
     4381 tcttttagtt cagctaaatc tatttcgtat acttcatcat agactgcatc ttcatctgct
     4441 tcatatatat ttacatcttt tgtcatagtt gaacacttat gtgaatttat atattccata
     4501 gtcttatcgt ctactggaaa aattccattt tttgctcctg cttctattgc catattacaa
     4561 atagtaaatc tatcatccat agataagtat tctactccat ctccacaaaa ttccattgac
     4621 ttgtaaagtg ctccatcaac acctatctcc cctattatat gaagtattat atctttacca
     4681 cttatccatt tatttggttt attcttcaaa acaaatttta ttgctccagg aaccttaaac
     4741 caacattttc ctgtagccat acctgctccc atatcagttg aacctacacc agtagaaaat
     4801 gctcctaatg ctccatatgt gcaagtatga gagtcagcac ctataattac atctccagca
     4861 gttactatac ctttttcagg aagaagaaca tgctctattc ccatatctcc tacatcaaaa
     4921 aaatttacaa ctccttttga ttttgcgaaa cttcttgtaa atttacattg ttctgcactc
     4981 tttatatctt tattaggtgt aaagtggtct aaaaccatca ctactttagt cttatcataa
     5041 acatcttcaa ttcctaattt ttcaaattct ctaatggcta ctggtgatgt tatatcatta
     5101 cctaaaacta catctaaatc tgcttcgatt aattgccctt tcttaacttc atttaattta
     5161 gcatgtttgg ctaatatttt ctgcgtcata gtcatcccca ttttttattt cctcctcaat
     5221 ataactttta tttattgcat tcataagtgc attaatagct gctgtattta tgttttccga
     5281 tatacttaca ccaaaataga cttcattatt gtgctctatt cctacataag ctacccctct
     5341 tgaatgtgac ccttcctcta atgcatgttc ccagtaatat ctaaatttat aatctttcat
     5401 gccacattgc tttagtgcat tattaaatga atctacaggt ccatttccta taccaacaat
     5461 cctttgttca tttcccatat aacttattct tgcagtcatc tcaatcatgt tagtatcatt
     5521 agaatcatca ttttcatagt ttaattcatc cattgatttt attttatact tcttaacttt
     5581 ataagggctc tcaacttcaa tatattcttt cttaaacaaa ttaaatattg cttcactact
     5641 aagttcttcc ccaattctat cagattccat tttgactaca tttccaaaat cagaatgcat
     5701 attcttaggt atcataaatc cataatctgt ttccattata taaacagctc ctccttttcc
     5761 agattggcta tttatcctta taatttcttt gtattctctt ccaatatcat gagggtctat
     5821 tggtaaatat ggaacttccc agtaatcatt atctctgttt ttcattgcta tcatgccttt
     5881 tctaatagca tcttgatgtg aacctgaaaa agcacaatgt acaagattac ctgcatatgg
     5941 atgtctatca tgtaccataa gttttgtaca gtcttcatat atacctatta tcttatctat
     6001 attgctaaaa tctagctctg ggtctattcc ttgtgtataa agattaagtc ccacatttac
     6061 tatatccata ttcccagttc tttcaccatt tccaaatagt gttccttcaa gtctatcggc
     6121 accagccaat aatccaagtt cacttgcagc cgtacaagtt cctctatcat tgtgagtatg
     6181 caaacttagt ataatagaat ccctacaact tatattttta caaaaccatt ctatttggtc
     6241 tgcatatacg tttggtgttg ccatttcaac tgttgatgga agatttatta ttactttttt
     6301 ttgaggagtt ggtttccaaa catctatcac tgcctcacat atttcaagtg cataatccat
     6361 ctctgttcct gtaaaactct ctggtgaata ttcaaaagta aattctgttt ctggatattt
     6421 ttttacttct tcattaaata attttgctcc ttcaactgct atatctatta tttcttgttt
     6481 actcatatta aaaaccacat ctctttgaag aacagatgta gagttatata aatgtataat
     6541 tgctttttta catcccctta ttgattcaaa tgttttttct ataagatgag ccctagattg
     6601 tgtaagtact tgtatagtta catcatctgg aatcatattc tcatctatta attttcttaa
     6661 aaatgtatac tctgtatttg atgctgatgg aaatcctacc tctatttctt taaatcctgt
     6721 atcaataagc attttgaaca ttctgacttt ttcatttaca ctcataggtg ttggcagtga
     6781 ctgatttccg tctcttaaat cgacactaca ccaaattgga gccttaaata tttcattatc
     6841 tggccattta cgatttacta tttgcatttt atcatatttt ttatactttc cacacttcat
     6901 gttatttccc cctttttttg ttttttgtat tcagtatacc tcatatcgac gcaatcctgc
     6961 acaattcata aggataaatg tcaattttat cattagaata aaaaaaacct catctctaat
     7021 aaaattagag acgaggtttt gctcgcggta ccactctatt tagctttcta aaaagctccc
     7081 ttagtaatag ccaatacaat aattataatg actatatttc ctataacgtg gaattactcc
     7141 gattattcta agatttaaat cttagaaaac agctcctaga caagttcaga actatcaact
     7201 actaaatcac accatccttt agctctctga aagtttcatt gttcttacta cttctattca
     7261 tcactttttt aatcatttaa attttctaaa tattttgatt taatagttat tatatacaca
     7321 ttaaaatgta ttgtcaacac aaaaaataat tatctcaatt ttttattttt gataagcaat
     7381 tctataaaac atgctaacta ttgaaaacag tatgatatta tgccttaaac tttttcatct
     7441 tttcatctat gatattcaat aatttttttt catcttccaa actcaatgcc cttaatctaa
     7501 ttttataatt agattcgtca gtgtatatat ttaatatatt ttttactact tctatttttt
     7561 ctattatctt ataattaaac ttttgacttt gtttagattt tatactgaat atacattgat
     7621 tatttattaa tattgaatga ttatcgagag taatatatac ttttccctca tatttatttg
     7681 aaaaatcacg accttgttta aatagaaaaa ctgctgttat tatacataaa atatataata
     7741 ttgtcgttga atatataaaa attgtagcta aaattataag tgctaaaacc atatatatag
     7801 tcattccttt tttaaaataa ccattgtcat aataattcat atagataaac ttatttttac
     7861 tcaaattttt tcactcccaa gattctaaaa atttatatca aaaaattcta taatttcatc
     7921 ttcatgataa tttatgacta attcatctgg aaaatctact gcttctaaaa ctttttctgc
     7981 attttcaaat tctcctatag aataacatat atgagagtca gtaccaagaa ttactcttgc
     8041 accatatgtt ttacacaatg tcaacatatg acttacattt tcccaagtac ccgttctatg
     8101 agagtttgaa cttaatgatg aattatttat ttctaaaagg atatttttat ctttagcttt
     8161 ttttactata ggttcataat ctaaaggata cctactgtca tctggatgtc caattatttt
     8221 taccttaggt ttatccataa cttttaaaat agcatttgta tttttttctt ttgtaccaga
     8281 ggctatacaa ggtctatgca aacttgcgat tatataatcc aaatgtttca acatatcttc
     8341 ttgaacatct aaattaccat tataatccat tatatttcct tctattcctc taagaatctt
     8401 tacgccttgc acttcacgtg gaagcaaatg caaattataa aaatagaatg gatgtggtcc
     8461 tcctggcata ttaggtccat ggtctgatat tcctaagtat tttatattct tcttactcgc
     8521 ctcttcgaca ttttccttga aagtactatg tgcatgtcca cttattagag tgtgacaatg
     8581 tacatccata atagactttt tcattaaatt tcctcctaat attttacata aattcgtgaa
     8641 aatagctaaa gggctatttc aaaactaaag ctgtcataat agacagtgta acgttttaaa
     8701 acagccccat tttcaattat tttacacttc taaatcttta aatttatctt taaataattc
     8761 tccaatactt cctaaagatt cctctacttc taggtattct gttatatcct cttctggctc
     8821 tctagttgct tcttttattg aaaccaacat tcttttagtc tttggtttaa aatcaagaat
     8881 cttaacttta acctcatctc caatattaac aacattagta actttagcca ctctagtatc
     8941 actcaattca gatattggta aatacgcatc tacaccttct ttaatttgaa caaaagcccc
     9001 tttttctatt attctaagaa ctttagcatt gacaacatca tcaatttgta cttcttttgc
     9061 tattaaatcc caagggtcat tatttatgtc ttttaatgcc aaggcaattt ttttagtctc
     9121 tttatttaca tccaacacat aaacttctac ttcttgtccc tctgaaacaa catcttcaac
     9181 actttcaact cttgtccaag ctaaattatt tatatgtgct aatccttcaa tcccaccaat
     9241 atccacaaat gcaccataag gcattatctt tgtcacctta ccatctcttt tttgtccaac
     9301 ttcaagagaa ttaaataagt cttctttagc tgctttgata cgagcttttt cttcttctct
     9361 ttcttgctta attcttgctc tttcagcttc tttttctgcc ttaatttgag ctcttctttc
     9421 ttctctctct ttatttatac gctcttgtaa tacatctcta tgagatgcta caagtctatt
     9481 ttttctaaca tccaattctt ttatataaac ttctaagtta agaccaacaa atttagatgt
     9541 atctgtaata aattttgtat caagttgaga aattggtata aaaaatgtat atgtattgta
     9601 attagcaaat acacctttat ctatattctt ttcaacattt acagttatta ttctatgttc
     9661 atcataagcc ttttgtaact tggcaaaatc atttcttttg tcaagttgta atttagataa
     9721 agttattgta ccatcttttt gagatacttt tgttattaca gcagttattt catcacctat
     9781 gtggtatata tcttctatat attgattttt ttctatgttc aattcactta taggtattat
     9841 tccatcaaac ccatagtcta atcctaattg tacttcatca tttctcactg cagttatttt
     9901 tccagttgtc aattctccaa ctttcacttt gctgaatact tgttcttgct ggtcaagtaa
     9961 ttcttgcatt gttaaatcat tttccattat aaacatcctt tcctcttatt gattatcata
    10021 tctgtaaata ttataccatt aatattgcaa atacttacat ttttcttact ataattttta
    10081 aaataaattc aacttcatat atttatacat tatagaaaat atcttattaa attaaaatac
    10141 aaattctaat ttttatctaa taaaatattt tcataaaaaa tttatattgt atatcttatt
    10201 cttttattgc tttaggtttt gatagaaaac atttataaaa tataaagaaa gaaattgctg
    10261 ttatagtagc agctgttata tctgcaactg gctctgctaa aattactgca aaaagttttt
    10321 cattaaagaa tgttgggagt ataaatatta aaggtattaa aagtacaatc tttctaagta
    10381 gagctaaaac caaagatatt gttgcttttc caagtgctaa aaatgtctgt tgacaagcta
    10441 tttgaatccc aaacataaaa gcaccagcaa aatatatttt tatactccaa ctagtcatac
    10501 taagtaactg cggattctta ttaaatatac taacaaaaaa tgcaggaaat atcattaata
    10561 aaagccataa aatagtagaa tatgtaaaac atgacaacaa acacaactta aatgtctttt
    10621 ttactctatc aagttgacct gaaccataat tataacttat tattggttgt gctccttgtg
    10681 taacccccat attaggaagc ataagaattt gcattatact gctcattatg gccattgaac
    10741 ctactgctaa atctcctcca tacatttgta atttactatt taaggctata agtactaaac
    10801 tttctgtaga ttgcattata aatggagaga ttcccaaacc aagcactggt aagatgatac
    10861 ttgcttttgg tatcatatac ttctttttta ttttaagtat acttttcttt ccaaagagaa
    10921 acataagtac ccaaatagca gaaacgcctt gtgcaattat agtagctaat gcagctcctt
    10981 ttacacccat attaaagcca aatataaaaa tcgggtcaag tattatgttt attaaagcac
    11041 ctatagcaac tgtcatcatt ccagttgtag caaacccttg ggtatttata aaagtattca
    11101 tacccattga aatctgaaca aacactgtac ctattaaata aatatttaaa tagtccattg
    11161 aatatccaat tgtagattca cttgctccaa acatccaaag taaaggctct tttccaatct
    11221 taaaacctat agtcaaaagt attgctaaaa tcaccagtac agaaaaactg ttactcatta
    11281 ttttctctgc ctcatcattg ttttgctcac ccatttttat agcagctaat ggacctcctc
    11341 ccataccgat taaataacta catgcagtta ttataattat tattggaaat gccactccaa
    11401 caccagccat agcaacttct ccattttcca ttctaccaat aaaaatccta tcgactatgt
    11461 tgtataaaac atttacaatt tgtgcgataa tagcaggtgt agcaagttta aataataatt
    11521 tacccacact ttcactacct aagttagtgt ttgaattttc cattttaaaa cctcctcaat
    11581 ccaataatta aaatgtatca ctaaaatttt attctatata aaaatttcat tttattagca
    11641 gacaaattta gagtactttc cctacaagta atactatact atatttcttt tgccatagta
    11701 aacattttag aactaactga agttaaatac tttatctcat tttttattta ttattaaaaa
    11761 tttttcacac atactcataa aaaaactatc caagtatatt acttagatag ttttatatta
    11821 tatgtaaaga aagagctgaa actataaccc ctgataacaa attaccaaga aatactccca
    11881 taaaagcatc ttttattctc atttttaata tggaagctat agcagatgca gtccatgttc
    11941 ctgtagttgg cagtggtata cctacaaata gtattatacc aattatcgaa acacttttta
    12001 atttcttcat tcttgagttt atttttctat caattacatc agcaatccct ttaaatagtt
    12061 tcttccctct taaaaattgt aatacatgtc tgaatgtcaa tatcaaggga atcgatacca
    12121 atgtagaacc tattacacta aatacataaa cccatatagg atttaagccc attgcaatac
    12181 ctataggaat ggctcccctc aattctgtta caggaaccat agataaaatt aatatgtgta
    12241 aatatcccaa actattccct cctattctaa gtgacattaa gttatgaatt tatttgctct
    12301 ataacctcac catccttttt actaactaaa aatgcatttt tagtcaatga aagcattggt
    12361 aaatcactct tagagtctga atatgcatat gaattttcat aatcaatctc tatcccaagt
    12421 ttacctaata cagcctttat tctttttaat ttttcaattc ccttacaatt ttctccaatg
    12481 aattgatttt tatatcttga attttcataa aaaaactccg tgcctataac ctcgtctgca
    12541 agaccataat acttaaaata tttcatatat gcatatggag atgcagttat cataattata
    12601 acattatctt cttctttatt tttgtaaata acctttttca tagattcgtt aatttttttc
    12661 attatgcaat catcaaaaaa cttttttaaa tcttcttcac taaaatctac tattggataa
    12721 aagattgcct cttttgcctt cttcaaaggt atcattctaa ttaaatacat aaatagaata
    12781 aaaataatgt atggcaactt tataatagtt ttaaaggttt tattttttaa agagtaaata
    12841 aaaaaatcta tcatgctatc agtatttata acagtataat ctacatcaag taataataca
    12901 ctttttttca taagtatttc cccatcctat cactaaaaat atcactaaaa aatcaatatt
    12961 attaaacatg taattatcca taagattacg tttattttta aagcattatc ttttaggaca
    13021 atatcagtag gattattttc atttgtagtg ttaattatat aattatatct aagtacacca
    13081 taaactacaa atattgttgt aaatatcata tgtggctttt ctggattact tgtagaatac
    13141 aatgcataac atacaattgt agaacttaat ataactatca tcatttgatt tagattttct
    13201 atgtcataat cttccaatat ttttctatgt tcaactgcat catctcttag agtttctatt
    13261 tcttttttac gttttccaag agctaagtac agagataaga aaaatgtaca taaaattatc
    13321 caatttgata aactaacact tatggctaca catcctgcat aaaccctaag tataaaacca
    13381 agagatattg aaaacacatc taatagtatt atattcttta gtttaagaga atataatata
    13441 ttgtttatca aatagagact gagaattata gaaagattaa aactaacaac tgttgataaa
    13501 cagactgaaa ttaaagctaa tactacaaat agtatattag cacttttttt gcttattctt
    13561 ccacttgcca ctggtctatt acatttttta ggatgttttt tatctttatc catgtctata
    13621 gcatcattca gtgcatatac tgatgatgac attaggcaaa aacacacaaa cgcaataaac
    13681 gtatttaaaa ataaatttat atttagtatg ttgtttgaaa aaattatagc tgaaaataca
    13741 aagaaattct ttatatattg ctttattctc attaacttta tataatctga aattttagta
    13801 agaagcctta tacttgtatt ggtctgtttc ataaacttac taccctttca atattatttt
    13861 ttaaacagga tatgatttta tccctatgtt taaaatttct ataaatccat tgacattact
    13921 gattactata gtaaccaata acagcgatag aaatatatta tacatattct tttcattttt
    13981 tctaagcgct ttcgtaaagt aagccaataa aattataact gcaaaactaa aatttatagc
    14041 cataatactt gaattgacta gattatatcc tactatacca tgtaaagtta gattgaatat
    14101 aattattccc atacatagct taggaactct tttttctgaa ttttcaataa ctgataaaac
    14161 acaaaaacat aaagctaata atgtaagaat tactggtatt gtagcaactt ctccattttg
    14221 caaaaataac ccttttttaa tgcttgctcc aggaaaataa aaaaccgaat acaataatct
    14281 ctctataatc attgcaatct tttccaaaat tggttctcca cttataaatt tcgtatcata
    14341 ctgtattaca tttccaaggt tcataaaact ctcataagac ttcgttgaaa ctacacaaat
    14401 atatgccatt aggataaatg taattaaatg ttttaacatt tttcctattt ttaatttaaa
    14461 ctcaaatatc atattaaaaa aatacaaata tatattacta atagttattc caaatagagg
    14521 aatagctgct aattctacta aataagaatt ttttcctttc atcttatttg caataactat
    14581 gaaaaatatt aatgaaaatt ggctatatat aaatctctct acatttaaag tcataaatag
    14641 ctgtggaaaa gaaaatatca ttatcatagt aagtaaaatt aaagttaatc tctgcatttt
    14701 tatcttttta atatgattaa agactaaagt tattgacata gcactagtta ttatttgtag
    14761 acaaattagt ccaaacccat aggcactatt aaaatctgtt gtcccaggat ttgctattga
    14821 agtacaaaat aggtatattg gatatgcaaa aattgatata attgctgaaa acaatatgtg
    14881 cttactattg tcttgactta tagcaaatac atttaaattg aataaaactc ctgtatctgt
    14941 atctaacaat acatcataag tattgtttaa atcataaaat atagtagtct tagaaaaaaa
    15001 tatcttagtt attattaagt aagttattac aactaatata aacaaaaaca tctcgttttt
    15061 atattttaat attttactca tcaatatatc accatccatt cattatatag gatttgctga
    15121 cacctacaat ttattcctta tatttaatag ccatcttcat aatgttctta cttgttttat
    15181 tgtaattgaa taactcttta tttacaacca caatatttac tttattgatg ttataatcag
    15241 tcaagtattg tttatataac atagattagt gttgtataaa atgagaattt gtaagcaata
    15301 ttaatgtaaa atatttgaaa aactttatat aaaaatatac aatgttgctt atggaattaa
    15361 actataacaa attaaagcat aatttaagga gacaaaatta taatctgtct ccttaaatat
    15421 taaaactata ttttaaaaca ttactaaata ctatacaaat ttcaaatata gtataaaatt
    15481 aattagactt taacactatt agctccatct tcttcccatt ttttaatttc ttttaatcta
    15541 tctattatag gtaaatgctg agtacattca acttcacatt ttccacaaga tatacattct
    15601 ttagcttttg ccttactatt cattgtgtaa ttccaatgtc ctaagccata aactaacttt
    15661 gtcatttctt catcactctt tttaaacatc tgcttttcat tataaaaaag catataggct
    15721 ggggtattaa taccttttgg acatacttta caataaccac aacctgtaca tatttcgttc
    15781 atattcttat ttaatctagt ctcaatatca tgtatatcct catctgaata aattctattt
    15841 tcgtctgcaa ttttacatgc atcatctata tcttgttttt tattaaaccc tatcaaagat
    15901 atacttattt gtgaaattcc tatgttgaat cttaaagctg attctatagt actttcgcca
    15961 tcttttgata gaaaagaaag ttctttatta tactttggaa tagttccacc acttaatgga
    16021 ttcattgcca caacaccata tccattatca acagcatatt tggcaccttt tagcctatat
    16081 ggaaagttta atatatttat tcccatagtt acaccttcaa acttattttc acttagaata
    16141 tctataacct catctcctgg ttgatgagat gaaaatacta tatggtctat caatccttct
    16201 tctttacatt tcaataatcc ttcatattga cctccaggtc tcattgctag ttcgtaatgt
    16261 tccatctttc taatattcca aacatgataa aaatttattt tagatacgcc taatcgttct
    16321 attgattttt ttacagcctc tatagctttt tctgatgtat cacatgcttt tggcttttct
    16381 ttagttgata cataaaaatc ggtcttacct tcctttatca tttgtctaaa ggctagtcca
    16441 aatatatctt cacttctgtc atcacaatac cctggtgctg tatcaaagta attaatacct
    16501 ttttcatacg catatttgac taaatcagca ttttcttgat tacttttttc taaatcaaac
    16561 cttaatcctc catagccaac tactgaaacc attttccctg tctttccata ttcaacgtat
    16621 ctcattgtaa attcctcctt agatatatta agacttaatt tctttataga aaatattata
    16681 ccat
//
LOCUS       DAMKNB010000076        16643 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.080, whole genome shotgun sequence.
ACCESSION   DAMKNB010000076 DAMKNB010000000
VERSION     DAMKNB010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 16643)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16643)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16643
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.080"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            115..2178
                     /locus_tag="PC494_002817"
     CDS             115..2178
                     /locus_tag="PC494_002817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HDF3913307.1"
                     /translation="MTKIILSNYRCFGEEPTTIEINNLTGFIGHNSSGKTALLSALMK
                     LFGEKSSDRIIERSDFHIPESIDPDSISKNELYIEAQFEFPELERGKDSISIPVFFKN
                     MVVSEPGGKPYLRIRLEANWEKSSNPEGSIDSNVYYITSTTEEINPEDKRNIKRYELD
                     QIKMIYVPAIRRPDEQLKNVSGTIISRLLNGISWSEQTKARIKTKASETEEIFFEEKG
                     VESLKKSLETQWNSYHKDIRYSNPKINFNSTDLETILKKVEVTFSPTGTHRDYRVEEL
                     GDGLRSLFYLSLVNTFLEIEEEILKSINDGKEEDIFTLIPPVLTIVAVEEPENHISPH
                     LLGRVVEKLNFISTKENSQTILTSHSPAIVKRIEPTDIRYFRICKEYECTKVKSIILP
                     NEEKEAEQFKFVKESVLAYPELYFAKLVVLGEGDSEEIIIKQMIELKAESVDSSEISI
                     VPLGGRHVNHFWRLLNDLEIPFITLLDLDRERDGGGWGRIKYAIQQLINIGHDKNVLL
                     YTCEGISQDNEFKEMHTWDVTDTENMAKWIEMLKGYDVYFSAPLDIDFAMLQSFKDKY
                     ISALTSAEGPRIKDHGKIQDIVINEDAEDESLKAAYKDRIDSDIKSTLKQEGGDGSTY
                     TEGEKELMIWYSYFFLGRGKPTTHLSLFSNNTDIDFESFPYCLKEFVNSIIEKMIDDS
                     GGGRK"
     gene            2175..4040
                     /locus_tag="PC494_002818"
     CDS             2175..4040
                     /locus_tag="PC494_002818"
                     /inference="COORDINATES: protein
                     motif:HMM:NF024642.1,HMM:NF024754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HDF3913308.1"
                     /translation="MKRNWVSKEDWSPAAGFRLEVEAMNTVINDKNTLVVAGPGAGKT
                     ELLAQRACFLLETNTCRYPKKILAISFKKDAAENLKERLELRCGKELASRFESKTYDA
                     FAKEIVDRFRNSLDEAYRPLNNYNIAENRDVRRAFEIAGLNFRGNQTEFNKVYGNKLS
                     INKLPLHTDFVDKIFIDAWNVLLKGNKDTNFVSSLTFGMISRLAEYLIRTNRYIKKAI
                     EMTYSHVFLDEFQDTKSIQYDLVKACFFKTETIITAVGDGKQRIMLWAGARKSIFEDF
                     QNDFLSQKRTLIMNHRSAPRLVEIQKAMYNSLNEEAIDLKTNEKWNYEDGEVYLRLFE
                     DYIKEADILSEEIVELVETGIEINEICILVKQSVDIYSKEIINKLSERNIKARNEAMY
                     QEILKEDIIKTLVSLFRLSLSDRNPDDWDYIYDILGELYGIDEGYNPKILNDFITKVE
                     LMINDLKVNLNITDEKQFSDLVDSKVEYISYEKFASKFQKYKSKDYFDDLVDKFKKLV
                     WIEYNETKDWIKAIDNFEGKNSIPIMTIHKSKGLEYDTIFFVGLEDSAFWNFKNQPDE
                     DRCAFFVALSRAKRRIDFTFSLDRPAGFSNSQKHYCINEFYELFDNTEIVKKIEY"
     gene            4164..4978
                     /locus_tag="PC494_002819"
                     /pseudo
     CDS             4164..4978
                     /locus_tag="PC494_002819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728762.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            5003..5491
                     /locus_tag="PC494_002820"
     CDS             5003..5491
                     /locus_tag="PC494_002820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HDF3913309.1"
                     /translation="MYEKDYKQYIKLDIPIDEAKIKNRFEIRLKNERAYHAAVDLLAN
                     RDEEKTAFSIINRYIRFVDKDDEKIRSEWKTNDQWSYFIGEGRAKLKLTTNPEPYNIQ
                     KTLNWLSRQVAPTLKTIKRLDSLNNSTLIEGLIRYARLTDKHKKIIEQNSVNVEDIIY
                     DE"
     gene            5604..5765
                     /locus_tag="PC494_002821"
     CDS             5604..5765
                     /locus_tag="PC494_002821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3913310.1"
                     /translation="MAIAIIGVYLGFKREFSKLIGFLVVALIAVGLVFNTAGVKDILL
                     ELFNKIIGV"
     gene            6005..6232
                     /locus_tag="PC494_002822"
     CDS             6005..6232
                     /locus_tag="PC494_002822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF3913311.1"
                     /translation="MDIVKVFANNVRKYRNKKGLSQEAFAEKAGLHRTYICAIERKKR
                     SIALDNVQKIADALEIETYLLFIEGEEKECL"
     gene            6229..9168
                     /locus_tag="PC494_002823"
     CDS             6229..9168
                     /locus_tag="PC494_002823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-6 DNA methylase"
                     /protein_id="HDF3913312.1"
                     /translation="MKKLPIEKLIENLGFSGSKNLVNIDMLTKLDISKHDVKTLKVIN
                     PYAIYLVNSKPFILFIESSFEEKKLQQISKLIWNAQIPIAFICDSNSVKIFNGKALDL
                     KSYLIEEIYNQSIEDFSEESEFSYLKISDPLFWDQYTKQYTKTHLNDYLLDNITSLTN
                     KLKKKYKVKFATKLVLRLIFIRYLIDRGVDIAYKNFNHDIKASQKELLKITKNKVELY
                     ELFKYLKEKFNGNLFELNDEINNTCLTDEVFILLSDFLSGKISIDNGQMSLFSMYDFN
                     IIPVELISNIYEILLGKEIRNKDNAFYTPNYLAEYILDKTTLEFLKNNRQYKILDPSC
                     GSGVFLVNSFRRIIDMNLGDKLFCEDDKLLKELLLSNIYGIDINEDAIDVTIFSLYLT
                     ILDYKDPKILSEFKLPNLKGCNLIASDFFDDNKLESLKKINFDFIIGNPPWGSVSDGL
                     HLDYCNKNGYNDMQQNKEISRSFIFRAKDFSSRNTVCSFVVHSKILYTQKKPSKKFRE
                     FLLKKSQIFSVVEMSSVRKLVFKNADAPAAVISFKYNESEENLNNRIIYTSLKPNVFF
                     KLFNIIVIEKYDVKYISQKLLLENDWAWKTIVYGFSKDIDIIMNIKKKYQTVNEIILK
                     NSFVHGTGIQINGNESHDATHLKGKWYVDSKKGIDSFYVDINKGKELTQDKMRRPKAN
                     QQEIFIPPYVLLKKGVDTKTYRYRAAFSNDAFVYSDAVTGICGKKDNLTTLYCLTGML
                     NSSFYSYLNIMLGTSIGIEREQGFSTEIFTYPAIESDEIANLVVKIQEATKLEKTTMF
                     LNEKNSCKYIKQLDKLILKSFNLNDDKFIDYAINIQIPELTNSKSTNIYRKITKEDLI
                     NYSECFKEQFSSIYRRVGKSISISVYPKILNRFTVFELEVTDEKTDREIMVKAEADNN
                     MELFTKIIRYDYNDVFHQIRDIIHFGENSFYIIKPNCYKYWHPAIAEMDLADVLDQIL
                     SDTGGEE"
     gene            9168..9842
                     /locus_tag="PC494_002824"
     CDS             9168..9842
                     /locus_tag="PC494_002824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3913313.1"
                     /translation="MGGFKNSSLNFYLKQGLYEIIIDGLIDCCLLMSKSCIEQSRKIL
                     NHEEKIRTHLVENYLENDIERRKTSLSKQHLRFEVEAQENYDNKNESYEGRVDIKVIS
                     KDTLADRRAYYIIECKRIDGKETLNKKYITEGVQRFITEKYSSHYGKNIMLGFIVKDI
                     NIQSNIQKINSLNQNILYTYIDTDMLTVRSDSENNYAVCESKYKVKSKLLLLNHIFYN
                     FSSIIR"
     gene            10003..10419
                     /locus_tag="PC494_002825"
                     /pseudo
     CDS             10003..10419
                     /locus_tag="PC494_002825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003455547.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
     gene            10379..12826
                     /locus_tag="PC494_002826"
                     /pseudo
     CDS             10379..12826
                     /locus_tag="PC494_002826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005423199.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
     gene            12966..13388
                     /locus_tag="PC494_002827"
     CDS             12966..13388
                     /locus_tag="PC494_002827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3913314.1"
                     /translation="MRLEDIIDKESYEEKYDDLTVEIKKLSKEKKTLKASLINEKSIK
                     ARLREFRKILERNELLEKFDRYVFASIVDKVIVGVINEDGIVDPYKITFVYKTSFDDK
                     QDGHKFINKSPLETYSKDNNDNKKKCSYTNNETLRDCS"
     gene            13926..14960
                     /locus_tag="PC494_002828"
     CDS             13926..14960
                     /locus_tag="PC494_002828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YHYH domain-containing protein"
                     /protein_id="HDF3913315.1"
                     /translation="MFKKKLIAVAMSITMISVGSFSYAHSGRTDSSGGHRDNKNKSGL
                     GSYHYHCGGYPAHLHNNGGCPYTGGGSSSGTTTSVNNEEKQKRSVGEKGYNQGYEDGY
                     KGNYSSSNYSGDYSDTYESKYSEGYEKGKAKLEEEEKVAKETGYNLGLTGAKSNNTYE
                     KEVLKNAYDTGYSTGYNEYKTKKIEEYKAKGIEDSNKDKEKMTFEENIDSEFIDAYNN
                     AYDERQEQLKNDYTTQGFESAIKGERFDTSTIGNVKYANWFKEGYDNGKVKLPKAKES
                     VYNQGYNEEDFSIPDEMKSIETKLKGVYDEGLEKREEEKSRNATYGVGAGTAAVVAGV
                     VYKKKKRKKI"
     gene            15047..15250
                     /locus_tag="PC494_002829"
     CDS             15047..15250
                     /locus_tag="PC494_002829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4236 domain-containing protein"
                     /protein_id="HDF3913316.1"
                     /translation="MGFNFRKSINLGGGLKLNLGKKSVGISAGVKGARVSVNSKGRKS
                     ATLSIPGTGISYTKTSTKKRKPK"
     gene            15421..16581
                     /locus_tag="PC494_002830"
     CDS             15421..16581
                     /locus_tag="PC494_002830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp27"
                     /protein_id="HDF3913317.1"
                     /translation="MKLSKILLAIGMSVSLLIASCPTSNALSSINSIKGTNKYETAGL
                     IADKQNYDIAILINSENGLSDGLSASGLSGAKNAPILLTKKDTIPSETLKRLEKVKEV
                     YLIGGKNSIGASVQKILSDKKISINRISGTDRIDTSHKVAKEIGRVSTVKKVILTNAF
                     KGEPDAMSVASIAVRDKSPIVLTDGNTTSFATDGLETYAIGGKVSMSDKLINETKATR
                     IGGVDRYDTNKQIINKFYNGSKEFYIASGTDLVYSLVGSTIAQKTPIVLVGNGSNKSI
                     LKNASKITAIGNIDDVVIKQCLNITNNVGDSNTGIVKDTNSNNTNKPSNEPSSNNPGL
                     TDKSTVYVTPNGKSYHLTKNCSTLKRSKTINKVTLKQAKSQGKIDPCNVCVK"
BASE COUNT         6799 a         1617 c         2917 g         5310 t
ORIGIN      
        1 tattcgtata ataatagaaa tattttagca taagatgtat aataaaggaa aaaatacaga
       61 attaaaaaac ataagataga taagtggact taggggagag aaattattat gcaattgaca
      121 aaaataattc ttagtaacta taggtgtttt ggagaagaac ctacaactat tgaaattaat
      181 aatttaactg gatttatagg tcataatagc agtggtaaaa ctgctttatt aagtgcactt
      241 atgaaacttt ttggagaaaa gtctagtgat agaattattg aaagatcaga tttccatata
      301 cctgaaagta ttgatccaga tagtatttct aagaatgaat tatatattga agcacaattt
      361 gagtttcctg aattggagag aggtaaagac agcatatcta taccagtatt ttttaaaaat
      421 atggttgtta gtgaaccagg tgggaaacct tatttaagaa ttagacttga agcaaattgg
      481 gagaaaagct caaatcctga aggaagtatt gattcaaatg tatactatat aacatctaca
      541 acagaggaga taaatcctga agataagcgt aatatcaaaa gatatgagct tgatcaaata
      601 aagatgattt atgtacctgc cattaggaga ccagatgaac agttaaaaaa tgtctcagga
      661 acaataattt caagattatt aaatggtata agttggtcag aacaaacaaa ggcaagaatt
      721 aaaacgaaag caagtgaaac ggaggaaatt ttctttgaag aaaaaggggt tgaatcatta
      781 aagaaatcac tcgaaactca atggaatagt tatcataagg atattagata ttctaatcca
      841 aagataaact tcaatagtac tgatttagag acaattttaa aaaaagttga agtaactttt
      901 tcacctacag ggacacatcg agattatcgg gttgaagagc ttggagatgg gttacgttct
      961 ttattttatc tttcacttgt aaatacattt ttagaaattg aagaagaaat tctaaaatct
     1021 attaatgatg gtaaagaaga agatatattt acattaatac cgcctgtatt aacaattgtt
     1081 gcggttgaag aaccagaaaa tcatatttca cctcatcttt taggaagggt agttgaaaaa
     1141 ttaaatttta tttctacaaa agaaaattca cagacaatat tgacatcaca ttcaccagca
     1201 atagtaaaaa gaattgaacc aacagacata aggtatttta ggatttgtaa ggaatatgaa
     1261 tgtacaaaag tgaagtcaat tatattacca aatgaagaaa aggaagcaga acaatttaaa
     1321 tttgtaaagg aatcagtatt agcatatcct gaactttatt ttgcaaaact tgttgtattg
     1381 ggcgaaggtg atagtgaaga gatcattatt aagcagatga ttgaattaaa agcagaatct
     1441 gtagattcat cagaaatttc aatagtacca ttaggtggta ggcatgttaa tcatttttgg
     1501 cgtttattaa atgatttaga aattccattt attactttgt tagatttaga tagagaacga
     1561 gatggaggtg gttggggacg tataaagtat gcaatacaac aattaataaa tattggtcat
     1621 gataagaatg tattacttta tacatgtgaa ggaatttcac aagataatga atttaaagag
     1681 atgcatactt gggatgtaac tgatactgaa aatatggcta aatggattga aatgctaaaa
     1741 ggttatgatg tttatttttc agctccgtta gatatagatt ttgcaatgtt acaaagtttt
     1801 aaagataaat atatttcagc attaacaagt gcggaaggtc ctaggataaa agatcatgga
     1861 aaaatacaag atattgtgat caatgaagat gctgaagatg aatcattgaa agctgcttat
     1921 aaagatagaa tagatagtga tattaaatca accttaaaac aagaaggtgg tgatggatct
     1981 acttatactg agggagagaa agaactaatg atatggtatt catatttctt tttaggaaga
     2041 ggtaaaccaa ctactcattt atctttattt tctaataata ctgatataga ttttgaaagt
     2101 tttccatact gtctaaagga gtttgtaaat agtattattg aaaagatgat agatgattca
     2161 gggggtggaa gaaaatgaag aggaattggg ttagtaaaga agattggagt ccagcggctg
     2221 gattcagact agaagttgaa gcgatgaata cagttattaa tgataagaat acacttgttg
     2281 tagctggtcc tggcgctgga aaaacagagt tattagctca gagagcctgc tttttactag
     2341 agactaatac ctgtagatat cctaaaaaaa tccttgctat tagttttaaa aaggatgctg
     2401 ctgaaaattt aaaagagcgt ttagaattga gatgtgggaa agaattagct tcaagatttg
     2461 aatcaaagac ctatgatgct tttgcaaaag aaatcgtaga tagatttaga aatagtttag
     2521 atgaagcata tagaccttta aataattaca atatagctga aaatcgtgat gttagaagag
     2581 catttgagat agcaggatta aatttcagag gaaatcaaac tgaatttaat aaagtatatg
     2641 gaaataaact atcgataaat aaattgcctt tacatacaga ttttgtagat aagattttta
     2701 tagatgcttg gaatgtacta cttaaaggca acaaagatac taattttgta agttcactta
     2761 cttttggtat gatatcacgt ttagccgaat atttgataag aaccaatagg tatattaaga
     2821 aagcaattga aatgacttat agtcatgtgt ttttagatga gtttcaagat actaaatcta
     2881 ttcaatatga tcttgttaaa gcttgttttt ttaaaacaga aacaataatt actgctgtag
     2941 gggatggcaa acaacgaatt atgttatggg ctggtgctag aaagtcaata tttgaagatt
     3001 ttcaaaatga ttttttaagt caaaaaagaa cattaattat gaatcatcgt tcagcgccaa
     3061 gacttgtaga gattcaaaaa gcaatgtata acagtttgaa tgaagaggca attgatttaa
     3121 aaactaatga aaagtggaat tatgaagatg gagaagtgta tttaagactt tttgaggatt
     3181 atataaaaga agctgatata cttagtgagg aaatagtcga attggtggaa acaggtatag
     3241 aaattaatga aatatgtata ttagtaaaac agagcgtaga tatttattca aaagagatta
     3301 taaataaact ttctgaacgt aatattaagg cgcgtaatga agcaatgtat caggagatat
     3361 taaaagaaga tataataaag acactggttt cgctttttag gttgtcgtta agtgatagaa
     3421 atcccgatga ttgggattat atttacgata ttctaggtga attatatgga atagacgaag
     3481 ggtataaccc taaaatatta aatgatttca ttaccaaagt agaattaatg attaatgatc
     3541 tcaaggtaaa tttaaatatt actgatgaaa aacaattttc agatttagtt gattctaagg
     3601 ttgaatatat ttcatatgaa aaatttgcat caaagtttca aaaatataaa tctaaagatt
     3661 attttgatga tttggtagat aaatttaaaa agctggtatg gattgaatat aatgaaacta
     3721 aagattggat taaagcgatt gataactttg aaggtaaaaa ttcaattcca ataatgacaa
     3781 ttcataaaag taaaggactt gaatatgata ctatcttttt tgttgggtta gaagattcag
     3841 cattttggaa ttttaaaaat caaccagatg aagatagatg tgcatttttt gttgcattat
     3901 caagagctaa aagaagaatt gattttacat ttagcttaga tagaccagca ggattttcga
     3961 attcacagaa gcattattgt attaatgaat tctacgaatt gtttgataat actgagattg
     4021 taaaaaagat agagtattga ttaagatgat aaaaacttta gtatattata ttttaagata
     4081 ttagttatat aagtagacat tgaatttatg tatttgatgt ctatttttta tataaaaata
     4141 tattaaagaa aggatgaatt tgcatgaaga aaaaaacaaa aatatctaaa aagattgtaa
     4201 gttttattat ggtttttata actatagtta ctactatact tacatcatca gtttcagctt
     4261 atgctagcga gttggatatg agtgaacaga caggctttaa ttatttaggt attagtccaa
     4321 ttacaggaaa aaaattaatc ataacattta tcgtatgaag atggataata aaattgtatt
     4381 ttgtgtagag ccaggaatta aaacttcaag tggaggagga tatatatcgg aggagttagg
     4441 agataaattt atatctacaa cacttccaaa ttatcataaa agaaaagctg aaatacttga
     4501 gaaggtaaat agacataata tattaccttc atggaataat gaaaaagttg cagttaaaag
     4561 tggagaaaca attgagttag aagataagaa tggtattatt agagaaatgc aattagaatc
     4621 aaataatact ggaacagata tattacttga agaaaatact ttgaaaatta cagcaaataa
     4681 aaattctaat tcaggagtta ttagttatat aaagattcct aaaaatgagg ttggaatatc
     4741 aatagtttat cgtaagcata actatcaaag cttatcagaa tttcatatgg aaagttcgat
     4801 gagtgcaaat ttaaatataa atgtaatcaa gttaggaatt gttaaagtaa aaaagattga
     4861 tgaaggcaca ggaaaggaat tagcaaatgc aaaacttaga tttgagtatg atggtgatag
     4921 taaagaaatt ataacgggtt ctaatgaaat tgctagtata gaagatatta ttggttgatt
     4981 aaaaagtgaa gtatactttt gtatctatga aaaagactat aagcaatata taaaattaga
     5041 tatacctatt gatgaagcaa aaataaaaaa tagatttgaa ataaggttaa aaaatgaaag
     5101 agcatatcat gcagcagttg atttgttagc aaatagagat gaagaaaaga cagcattttc
     5161 aattattaat cgttatatac gttttgttga taaagatgat gaaaaaatta gaagtgaatg
     5221 gaaaactaat gatcagtgga gttattttat tggtgaaggt agagcgaagt taaaactaac
     5281 aacaaatcca gaaccatata atattcaaaa aactttaaat tggttatcaa gacaagttgc
     5341 accaacgtta aaaacaatta aaaggttaga tagtttgaac aactcaacat taattgaggg
     5401 cttaataagg tatgcaagac taacagataa acataaaaaa ataattgaac aaaattcagt
     5461 aaatgttgaa gacattattt atgatgaata aaaaaatgta attagtattg cagattttaa
     5521 tataaaagaa gggagatata cgaatgaatt ttggtcaaaa tttatataat tagtttttat
     5581 caaatgcaca atcattggta ttaatggcta tagctataat tggtgtatat ttaggattta
     5641 agagagagtt ttcaaaactt ataggatttt tagtagttgc attaattgca gtagggcttg
     5701 tgtttaatac agcaggagtt aaagatatat tattggagct atttaataaa ataataggtg
     5761 tgtaaggatt aaaagagaat agaaaattat gagtatatga tgaagggttc taataagttt
     5821 tattaaaata tatattgaaa gacaagtaga gctatttcga gttattacat gtaatgctaa
     5881 tatatataac tgcattttgg aaattaaata cataattaga aatagcaaat tttataggtg
     5941 acttattaat atgtttactt attgtatact atttgatata tttaatatga ggtgattctt
     6001 gaaaatggac atagtgaaag tttttgctaa caatgtgaga aaatatagaa ataaaaaagg
     6061 tctatcacaa gaagcttttg ctgaaaaagc tggattgcat agaacttata tttgtgctat
     6121 tgaaagaaaa aagagaagta ttgctttaga taatgtgcag aaaattgctg atgcgcttga
     6181 gattgagact tacttactat ttatagaagg tgaggagaaa gaatgtctat gaaaaaatta
     6241 ccaatagaaa agcttataga aaatttaggt ttttcagggt caaagaatct tgtgaatata
     6301 gatatgctta caaaattaga tatatctaaa catgatgtaa aaactttaaa agttataaat
     6361 ccttatgcaa tttatttagt aaatagtaag ccatttatat tatttataga gtcttctttt
     6421 gaagaaaaaa aattacaaca aattagtaag cttatatgga atgctcaaat accaattgct
     6481 tttatatgcg attctaattc tgttaaaata tttaatggaa aagctttgga tttaaagtca
     6541 tatttaattg aggaaatata taatcaatct attgaggatt tttcggaaga atctgagttt
     6601 tcttatttga aaatatctga tccattattt tgggatcaat acactaaaca atataccaaa
     6661 acgcatttaa atgattattt gctagataat attacttcat tgacaaataa attaaagaaa
     6721 aaatataagg tgaaatttgc aacgaagctt gttctaagat taatatttat tagatattta
     6781 atcgatagag gtgtcgatat agcttataaa aattttaatc atgatattaa agcttcacaa
     6841 aaagaactgc taaagattac taaaaacaaa gttgaattat atgaactgtt taaatactta
     6901 aaagaaaagt ttaatggtaa tttatttgag ttaaatgacg aaattaataa tacttgttta
     6961 acagatgaag tgtttatttt actatctgat tttttatcag gtaaaataag tattgacaat
     7021 ggacaaatgt ctttattttc aatgtatgac tttaatatca taccagttga actaattagt
     7081 aatatatacg aaattctttt aggaaaagaa attcgtaata aagataacgc attctatact
     7141 ccgaattact tagcagaata tattttagat aaaacaacac ttgaatttct gaaaaataat
     7201 aggcaataca aaattctaga tccttcttgt ggatcaggag tatttttagt aaatagtttt
     7261 agacgtatta ttgatatgaa tttgggtgat aaactttttt gtgaagatga taaactttta
     7321 aaagaacttt tattatctaa tatttatgga attgatatca atgaagatgc tatcgatgtt
     7381 actattttct cgttatatct aactatttta gattacaaag accctaagat attatcagaa
     7441 tttaaactgc ctaatttaaa agggtgtaat ttaatagcga gtgatttttt tgatgataat
     7501 aaattggaga gtttaaagaa aattaacttt gattttatca ttggaaatcc gccttgggga
     7561 agtgtctcag atggattaca tttagattat tgcaataaaa atggctataa tgatatgcaa
     7621 caaaacaaag aaatcagtag aagttttatt tttagagcaa aagattttag ctctagaaat
     7681 acagtatgtt cttttgtagt gcattctaaa atactatata ctcaaaaaaa gccatcaaaa
     7741 aaattccgtg aatttttgct taaaaaaagt caaatattta gtgtagttga aatgtcatct
     7801 gtaagaaaat tagtgtttaa aaatgcagac gctcctgcag cagttatatc atttaagtat
     7861 aacgaaagtg aagaaaattt aaataataga atcatctata catctttaaa accaaatgta
     7921 ttttttaaat tatttaacat tattgtaatt gaaaaatatg atgttaaata tatttcacaa
     7981 aaactattat tggagaatga ttgggcttgg aaaactattg tgtatggatt cagtaaagat
     8041 atagatataa ttatgaatat caaaaaaaaa tatcaaactg taaatgaaat tattttgaaa
     8101 aacagttttg ttcatggaac agggatacaa atcaatggta atgaaagcca tgatgcgaca
     8161 catttaaaag gaaagtggta tgttgattca aagaaaggaa tagattcatt ctatgttgat
     8221 ataaataaag ggaaagaact tactcaagat aaaatgagaa gacctaaggc taatcagcaa
     8281 gaaatattta ttcctccata tgtattatta aaaaagggag ttgacacgaa aacatataga
     8341 tatagagcag cattttcaaa tgatgcattt gtatattcag atgcagttac aggaatatgt
     8401 ggaaaaaaag ataatttaac tacactttat tgcttgactg gtatgcttaa ctcttctttt
     8461 tactcatact taaatataat gctaggtaca tcaattggaa tagaaagaga acaaggattt
     8521 tcaacggaaa tttttacgta tccagcaata gaaagtgatg aaattgctaa tctggtagta
     8581 aaaatacaag aagcgactaa attagaaaaa acaactatgt tcttgaatga aaaaaatagt
     8641 tgtaagtata tcaaacaatt agataagtta attttgaagt cttttaattt aaatgatgat
     8701 aaatttattg actatgcaat aaatattcaa attcctgagc ttacaaattc taagtcaact
     8761 aacatatata gaaaaataac taaggaagat ttaattaatt atagtgaatg tttcaaagaa
     8821 cagttttcat cgatatatcg tagggttggg aaaagtattt caatttcggt atatccaaaa
     8881 atattaaatc gttttacagt atttgaacta gaagtaacag atgaaaaaac agatagagag
     8941 attatggtta aagcagaagc tgataataat atggagttgt ttacgaaaat aattagatat
     9001 gattataatg atgtttttca tcaaattaga gatattattc attttggaga aaattcattt
     9061 tatatcataa agcctaattg ctataaatat tggcatcctg ctatcgcaga aatggatctt
     9121 gctgatgttt tggatcagat tttatctgat acagggggtg aagaataatg ggaggattta
     9181 aaaattcttc actaaacttt tatttaaagc aagggcttta tgaaataatt atagatggat
     9241 taatagactg ttgtttactt atgagcaaat catgtattga acaatctaga aaaatattaa
     9301 atcacgaaga aaagataaga acgcatttag ttgaaaatta tttagaaaat gatattgaaa
     9361 gaagaaaaac atctttatct aaacaacatc taagatttga agtagaagca caagaaaatt
     9421 atgacaacaa aaatgaatct tatgagggta gggttgatat aaaagttata tctaaagaca
     9481 ctttagcgga tagaagggct tattatatca ttgaatgtaa aaggatagat ggtaaggaaa
     9541 ctttaaataa aaaatatata accgaaggtg tacaacgatt tattactgag aaatattctt
     9601 cgcattatgg caaaaatata atgcttggat ttatagtaaa agatataaat atccagagca
     9661 atatacaaaa aattaattca ctgaatcaga acatattata tacatatata gatacagata
     9721 tgttgacagt tagaagtgat tctgaaaata attatgctgt ttgtgaaagt aaatataaag
     9781 taaaatctaa actactattg ttaaatcata ttttttataa cttttcgagt ataataagat
     9841 aatcttatga atataaaata ttactatgtt aaaattatag tttggttttg ataatattat
     9901 aaaaataagt ttaagaataa aatataaagg aaaaaagggg cgtagcacta ttttttagtg
     9961 tgacagcccc tttaatttta aaatcggtaa ggaggagtgt atttgaaaaa aattaagtca
    10021 tatacaggga ttttgaatgt ggagaaggtt atatatgcaa taaatgattt tcagcttcca
    10081 tttccagtta cttttacgca gatgacatgg tttgtattaa cactttttat aattatatta
    10141 tttggtaagt tacctccatt atttatgata gaaggagcat ttttaaagta tcttggcata
    10201 ccaattttta taacttagtt tatgtctcaa aagacttttg atggaaagaa accatatgga
    10261 tttttaaagt caataatact atattcatta agacctaaaa taacatacgc aggaaaaaac
    10321 attaaattta aaaataaaat tattgatgaa aatataacta tagtaaggag tgaattatat
    10381 gttcccgata aaatatatag agaacaatct tgtatttaat aaggaaggag aatgttttgc
    10441 atattatgaa ttaataccat ataattattc attcttataa gctgaacaaa aatttattgt
    10501 acatgataat tttaggcaat taatatcaca aagtagaaat ggtaaaattc atgcacttca
    10561 aatagccact gaaagttcta taagagttac acaagaaagg ttaaagaaaa atattacagg
    10621 aaaattaaaa gaaattgctt atgaaaaaat agacgagcaa acagaggcac ttgtttctat
    10681 gattggcgat aatcaaattg attatcgttt ttttattggg tttaagcttt tagttacaga
    10741 gaaagaaatg aatataaaga gtataaaaaa gtcaatatta gctaatctat cagattttat
    10801 atatgatgtt aataataaat tgatggatga ctttgtcagt ataaataatg atgaaattat
    10861 gagattttta aaaatggaaa agttattaga aaataaaatc tcaagaagat ttaaagttag
    10921 aaggttagat aaaaatgatt ttggatattt aattgaacat aattatggaa agaaaggcac
    10981 agtttttgaa gattatcaat accatttacc tacaaagaaa cttaaaagag aaacattagt
    11041 aaagaaatac aatcttataa agccaactag atgtcttata gaagagaagc aaagatactt
    11101 aaaaattata catgaggatt cagaaagttt tgtagcttat tttactattg aaattattat
    11161 tggagaaatg gattttccat ctagtgagat attctattat cagcaacaac agtttgcatt
    11221 tcctattgat actagtatga atgtggaaat tgtaacaaat aaaaaggctt taactacagt
    11281 tagaaataag aaaaaagaat taaaagattt agacaatcat gcttggcagt cagggaatga
    11341 aacagtaaca aatgtagtag aagcattaga ggctgtaaat gagcttgtaa ataatttaaa
    11401 tcaaacaaaa gaatcaatgt ataagttaag ctatgtaatt agggtatcag cagatagcat
    11461 tgatgaatta aaacgccgtt gtgatgaagt taaagatttt tatgacgatt taaatataaa
    11521 attagtacgc ctaatgggag atatgatagg atttcacaat gaatttatac cttcaagcaa
    11581 aaggtatata aatgattata ttcaatatgt aactagtgat tttctagcag gattagggtt
    11641 tggagcaact caatagcttg gagagaacga aggaatatat attggatata gtttagatac
    11701 aggaagaaat gtctatcttc aaccatctct tgcaagtcaa ggagtaaaag aatctgtaac
    11761 taatgcgttg gtagcagcat tctttggatt tttaggaggt gggaaatcat ttgctaataa
    11821 cttacttgtt tactattcag tattgtttgg agggcaagct gttttggtgg atccaaaagc
    11881 tgaacgtggc aaatggaaag aaaatttacc agatatatat catgaagtaa atattgttaa
    11941 tttaacaagt gatatagaaa ataagggaat gctagatcct tatgtaatta tgaaagaagt
    12001 aaaagatagt ggaagtctag ctattgatat attaactttt cttacaggaa taagtagtca
    12061 tgatggagag cagtttccta tacttagaaa agcaatcata aatgttactc aagacaaatg
    12121 cagaggactt ttgaaggtaa tagatgaatt aaggaaagat aattctcaaa tatcaaataa
    12181 tattgcagat catattgaaa gttttacaga ttatgatttt gcacaattac ttttctcaga
    12241 tggaaatatt aaaggctcaa ttaatctaga aaaacaaatg aatataatac aagttgcaga
    12301 tcttgtttta ccgaataaag atactttatt tgaagaatat acaacaatgg aaagtctttc
    12361 agtagctatg ttgatagtaa ttagtacttt tgcattagat tttatccata cagatagaag
    12421 tacttttaaa atagtagatt tagatgaagc ttggacattt cttaatgtag cacaaggaaa
    12481 aactttatct aataaattag ttagagcagg atgtgctatg aatgcaggag tgtattttgt
    12541 aactcaaaat gcaggtgatg tatcagatga aaatttaaaa aacaatattg gattaaaatt
    12601 tgcattcaga agcacagata tcaatgaaat taagagaata cttgaatttt ttggagttga
    12661 taaggaagat gagaataatc aaaaaaggtt aagagagtta gagaatggac agtgtttaat
    12721 acaagattta tatggacgag ttggggtaat acaaatacat ctagtttttc aagaactcct
    12781 tactgcattt gatacaagac cacctataag aaaagaggtg gattaatgaa atcgaaagta
    12841 tttagaaatt taagctggat aactatttta atagtagtac ttttactatt ttttatttat
    12901 ataaatttat agatttagag aaacaaatag atacattaga taagaaaaga aaaaaactca
    12961 tagatatgag attagaagat ataattgata aagaatcata tgaagaaaag tatgatgatt
    13021 taacagttga aataaagaaa cttagtaaag agaaaaaaac tcttaaagca tcattaataa
    13081 atgaaaagag tataaaagca agacttagag aatttagaaa gatacttgaa agaaatgaat
    13141 tgttagaaaa atttgataga tatgtatttg caagtatagt agataaggtt atagttggag
    13201 ttattaatga agatggtata gttgatcctt ataaaataac ttttgtttat aaaactagct
    13261 ttgatgataa acaagatgga cataaattta taaataagag tccgttagaa acgtattcaa
    13321 aagataacaa cgataataaa aagaagtgtt catatactaa taatgagaca ttgcgagact
    13381 gtagttaaac ttattagaga ataacaaggt ttcagacttt tatattgtgt cttaaaagta
    13441 gatttgccac ctatttgcca ccataattat ttttgggtgg caaatttatt ctacaatgat
    13501 ttcaaaaata tttaccgtct ggtttctcat gttgttagtt acatgtaaat atgtatccat
    13561 agttgttgaa gttttagcat gtccgagtat atgctggata tcttttatat tagtaccatt
    13621 ttctaataac atagtatcag ggtttttaaa ataaagtgtg tattcttcta aagtagtgat
    13681 aattaaaata tcaaatatca ctatacaaag gaaagtgcac gctttttatg tttaacaaaa
    13741 acgaaatatt aaaaaactta ttgaagaata tgatgtcaaa acaactacag atattcaaga
    13801 tatgctaaaa gatttattta caaatacaat tcatcaaata tttacattgt cgaattttag
    13861 cggtttaaac ataatatatt gactgatata ataaaatcat agaatatttt agggggaaat
    13921 agattatgtt taagaaaaag ttaatagctg ttgcaatgag tataactatg attagtgtag
    13981 ggagcttttc gtatgctcat tcaggaagaa ctgattcatc aggaggtcat cgtgataata
    14041 aaaataaatc tggattagga agttatcact atcattgtgg tggttatcca gctcatttac
    14101 ataataatgg tggttgtcct tatactggag gaggaagcag ttctggaaca acaacttcgg
    14161 ttaataatga agaaaagcaa aagaggtctg ttggagaaaa aggatataat caagggtatg
    14221 aagatgggta taaaggaaat tatagttcat caaattatag tggagattat agtgatacat
    14281 atgaatcaaa gtactcagaa ggatatgaaa aaggtaaggc taaattagaa gaggaagaaa
    14341 aggtggctaa agagactgga tataatttag ggcttacagg tgctaaatct aataatacat
    14401 atgaaaaaga agttttaaaa aatgcttatg ataccggata ttcaactgga tacaatgaat
    14461 ataagactaa aaagatagaa gaatataaag ctaaagggat agaggatagc aataaagata
    14521 aggaaaaaat gacatttgaa gaaaacatag attctgaatt tatagatgct tataataatg
    14581 cttatgacga aagacaagaa caattaaaaa atgattacac tactcaagga tttgagagtg
    14641 ctatcaaagg agaaagattt gacacatcaa ctataggtaa tgttaaatat gctaattggt
    14701 ttaaagaagg atatgataat ggtaaggtta agttacctaa agcaaaagaa agtgtatata
    14761 atcaaggtta caatgaagaa gattttagta taccagatga aatgaagtct attgaaacta
    14821 agttaaaagg tgtatatgat gaaggtttag aaaaaagaga agaagagaaa agtagaaatg
    14881 ctacttatgg ggttggagct ggaacagcag ctgtagttgc tggagtagta tataagaaga
    14941 aaaaacgtaa aaagatatag atgctagata taccaatgat gacaagtgta taacaaatat
    15001 aattttaagt ataaatattt aaaatataga agggaaggtt atatctatgg gatttaactt
    15061 taggaaaagc ataaatctag gaggaggact caaattaaat ttaggtaaga agagtgtagg
    15121 tataagtgct ggtgttaaag gtgctagagt gtcagttaat tcaaaaggaa gaaaatcagc
    15181 tacattgagt atacctggaa ctggaatatc atatacaaaa actagtacaa agaaacgtaa
    15241 acctaaataa atatttgata tactaagaaa tagactgtta caaatagtct attttttagt
    15301 atatagattt aaaaagtgac aaaattttga aatataaact aatttcataa aggaaaatat
    15361 tattttatgt agaattataa tatttaagta atattataaa atttatagga ggatttcatt
    15421 atgaaattaa gcaaaatact attggcaata gggatgtctg tttcattatt gattgctagt
    15481 tgtccaacat caaacgctct tagttctatt aattcaataa aaggtacaaa taagtatgaa
    15541 acagcaggtt taatagcaga taaacaaaat tatgatattg caatacttat taattctgaa
    15601 aatggattat ctgatggatt gtcagcaagt ggattgtcag gagctaaaaa tgccccaata
    15661 ttgttaacta agaaagatac aatcccttca gaaacattaa aaagattaga aaaggtaaaa
    15721 gaagtatatc taattggagg aaaaaattcg ataggagcat cagttcagaa aatattaagt
    15781 gataaaaaaa taagcataaa tagaataagt ggaactgata gaatagatac aagtcataaa
    15841 gttgcaaaag aaataggaag agtaagtacg gttaaaaaag taatattaac taatgctttt
    15901 aaaggcgaac cagatgctat gagtgttgct tctatagcag ttagagataa atctccaata
    15961 gtattaactg atggaaatac tacaagtttt gctacagatg gattagaaac ttatgcaatt
    16021 ggtggaaaag tcagtatgag tgataagtta ataaatgaaa ctaaagcaac aagaataggt
    16081 ggagtagata gatacgatac aaataaacaa ataataaata aattttataa tggctcaaaa
    16141 gaattttaca tagcaagtgg gactgattta gtttattctt tagttggttc tacaattgca
    16201 caaaaaacac ctatagtgtt agttggaaat ggaagtaata agagtatatt aaaaaatgca
    16261 agtaaaataa ctgctattgg aaatattgat gatgttgtta taaaacaatg tttaaatata
    16321 actaataatg ttggggattc aaatacaggt attgtaaaag atactaattc aaataatacg
    16381 aacaaaccaa gtaatgagcc tagctctaat aatcctggat taactgataa aagtacagta
    16441 tatgtaactc ctaatggaaa atcatatcat ctaacaaaaa attgttctac actaaaaaga
    16501 agtaaaacaa taaataaagt aacattaaaa caagctaagt cacaaggtaa aatagatcct
    16561 tgtaatgttt gtgtaaaata atgtattagc caaatatata ttaaaaaaga caattaatta
    16621 agattgtctt ttttattgaa gaa
//
LOCUS       DAMKNB010000077        16610 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.081, whole genome shotgun sequence.
ACCESSION   DAMKNB010000077 DAMKNB010000000
VERSION     DAMKNB010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 16610)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16610)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16610
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.081"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            143..811
                     /locus_tag="PC494_002831"
     CDS             143..811
                     /locus_tag="PC494_002831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3913318.1"
                     /translation="MSKLESTTEKVEVKWYGYVALILGALFFSGIFKDAPGPLKVLDF
                     NNVLGSFGTLGTINDGVGTLAANFRGDGGTGPRDGWLYALTLIPSVMFALGVVRVIDH
                     LDGMKAAQKLLSPLLKPLLGLPGFAGLTLIASLQSTDAAASMTKELKDDGYIDEKQKA
                     VFCAFQFSGASAITNFFASGAALFPFIGDVPIFIPLALILIMKFVGANLLRLYLNKFD
                     KGEA"
     gene            813..1298
                     /locus_tag="PC494_002832"
     CDS             813..1298
                     /locus_tag="PC494_002832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004455006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjiG family protein"
                     /protein_id="HDF3913319.1"
                     /translation="MSEVAKKEVKVKKGNVIDAFIGGARNGFQISTNSMAPNVIFGFA
                     IISVFNLTGLLDVIGTIFTPVMSIFGLPGVAATAIMTIFISMGGASGVIAGLFTAGQI
                     SQAHVAILLPMLLLSGAQIQFMGRLLGTAELKTKYYPHMFVIATLNGCIAMLIMNYFV
                     V"
     gene            1359..2480
                     /locus_tag="PC494_002833"
     CDS             1359..2480
                     /locus_tag="PC494_002833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 peptidase aminoacylase family protein"
                     /protein_id="HDF3913320.1"
                     /translation="METNKDYIEYVHKVYDYLHTIPEKGFEEYKTSEFVLKELEKMGF
                     ENINKGIAGTGIIVTIDSKKEGPVFAIRADMDALEFIIDGEKKMIHACGHDGHTSMLL
                     TAAKLIKERNLVKRGKLKILFQPGEEKLYGALRVIDSGLLDDVEEMVGMHLRPGQDCR
                     LGKAIPAMYHCASCIMEFTIKGITCHGSKPHLGVNAVDAVCLAVNAINAIRVNPAIPN
                     SIKVTNISVKGETYNNIPDEAFMALDIRAESNDIIEELKEKAIHAVKTAVSSINAEAV
                     LISKDGVPAAEFDEELVNLAEETIKDVLGADASIGIFKNSGGEDFHYYTQKLKCKTTY
                     IGLGADATPGFHNPNVTFDTKALEYGVDIWCRLVEKRLG"
     gene            2761..3951
                     /locus_tag="PC494_002834"
     CDS             2761..3951
                     /locus_tag="PC494_002834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HDF3913321.1"
                     /translation="MSKYNFDRVIDRVGTDCVKWDFRTNCSTKAQKDGLPFWIADMDF
                     ECAEPIIEALRKKVEHKIFGYSSNDSDKYFNAVCDWYKRRFNWEINRKDIIFSPGVVP
                     AVAILVRILTNSNEGVIVQKPVYYPFEAKIKSNNRDVVNNPLIYENGTYRMDYDDLEE
                     KAKCSNNKVLILCSPHNPVGRVWREDELKKVVEICKKYDLWIIADEIHSDLIRKGFKH
                     TPLQSLCPEYKDKIVTCIAPSKTFNLAGMQLSNIIVNNDELKKKYQEEVTAVGVATSP
                     NPFAIVATIAAYNESEDWLNELNDYLDNNIQFIDEYLKENLPKVKLVYPEGTYLAWLD
                     FTAYGLNEVELEDLMFKKANVLFDEGYIFGKEGIGFERINVACPQSLLKECMDRLKTI
                     FENL"
     misc_binding    4085..4340
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            4399..5400
                     /locus_tag="PC494_002835"
     CDS             4399..5400
                     /locus_tag="PC494_002835"
                     /EC_number="6.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--ammonia ligase"
                     /protein_id="HDF3913322.1"
                     /translation="MSTIIPKDYKSSLNVIDTQIAIKKLKDFFEMRLSNELNLIRVSS
                     PLFVLPETGANDNLNGEKAVSFDIPFMNKNAEIVQSLAKWKRLALKKYGFEVGSGLYT
                     DMNAIRKNEELDNIHSLYVDQWDWELVIDKSSRNEKTLKDVVKRLYGVFKDTEIFVCS
                     MYEGIKEILPEEITFITSQELEDMYPELSPKEREDKIVKEKKAVFITQIGKTLISGEK
                     HDGRSPDYDDWELNGDILFYNPVLDSALELSSMGIRVDEESLDRQLKLAGCEERKEFD
                     YHKMLLNGELPYTIGGGIGQSRICMYFLQKAHIGEVQVGVWPQDMIQNCSSAGIELL"
     gene            5504..5893
                     /locus_tag="PC494_002836"
     CDS             5504..5893
                     /locus_tag="PC494_002836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004455003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1232 domain-containing protein"
                     /protein_id="HDF3913323.1"
                     /translation="MEFLKIIINIVLDILKKILVRFKNAKFGLVFVFDLLKLPDFMTD
                     KRINIVDKIKVISVLIFTISYFVSGVDIIPEMIAGAFGFIDDAIVLIWSIGIVNEEIN
                     KYRVIAKKDKHSNIIENVEFSIKDEEE"
     gene            6054..7262
                     /locus_tag="PC494_002837"
     CDS             6054..7262
                     /locus_tag="PC494_002837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dicarboxylate/amino acid:cation symporter"
                     /protein_id="HDF3913324.1"
                     /translation="MKKKIGLVPKLIIGIIVGILIGSYAPEIIVQILVTVSTLFSAFL
                     KFVIPFIIIGFVTAGIADLATGAGKLLGITTGIAYGSTLIAGLLSFAVSTLIFPNFID
                     ASVASQIGDPEAGMLAPIFTIPLEPMVDVTAAIVFAFVMGLGISALRNHGKGETLFNF
                     FQEFQGIVTKTLSTVIIPLLPLYIAGTFANITIAGEVWTILGVFWKVYLVVIPLHFVY
                     MACQFTAAGVFSGKNPVRMLKNQVPGYLTAIGTQSSAATIPVNVGCAEKNGVSKQIRE
                     FVVPLCATIHLSGSMISITGFTTAVLMMNGMPHGIGVLFPYIAMLGIAMVAAPGAPGG
                     AIMSALPFLPMVGIPSDGGLASLMIALYLTQDSFGTACNVSGDNAIAVVVDKINDGMS
                     KKGNKEEQSA"
     gene            complement(7348..8424)
                     /locus_tag="PC494_002838"
     CDS             complement(7348..8424)
                     /locus_tag="PC494_002838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003415975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HDF3913325.1"
                     /translation="MSTNHGANLYSLSSKYGFSKEEFMDFSSNINPFGTSSLAKQYIV
                     NNIDMVSMYPDPDYIDLKTSISNYCKCSIDNIVLGSGATELISSFIHTINPKQALLLS
                     PAYSEYEKELSKINCSIEKYFAKEEDNFHINLENLIKTINAKDYDLVVICNPSNPTGF
                     AFTKVEVREILKNTDSFLMIDETYVEFTDTDTYSCTQLVDDYSNLFVIRGTSKFFSTP
                     GIRLGYGLISNTNVKNEINKNLDLWNINIIASKMGEIMFSDLDFISNTISLMNTERDY
                     LLKELKNIKSLDIYNTKGNFILCKIKTKELTAKSLREQLLPQKIIIRDCCSFEGLDEY
                     FFRVCILKPNENKLLISSLKAIFK"
     gene            8653..9180
                     /gene="hpt"
                     /locus_tag="PC494_002839"
     CDS             8653..9180
                     /gene="hpt"
                     /locus_tag="PC494_002839"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HDF3913326.1"
                     /translation="MYKVTGKMLTEEQIKEKVYELGKKIEEDFKGEDLLVVGILKGAS
                     VFVSDLIRCIDLDVNIDFMSVTSYGNSTESSGTVKILKDLDVDIEGKNVLIVEDIIDS
                     GLTLSNLVAALKTRNPKSLKLCTLLDKPQRRKANIPVDYVGFVIEDKFIVGYGIDYAE
                     KYRNLPYIGIVEDVE"
     gene            9269..10201
                     /locus_tag="PC494_002840"
     CDS             9269..10201
                     /locus_tag="PC494_002840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HDF3913327.1"
                     /translation="MDIQLNILLFFQNLRNPILNFIFLVFTISTEAPLLILITTIIYW
                     CINKKCGQKILFAIIGNFVVNLGIKEFVKAPRPIGIKGLESLRVSTAGGYSFPSAHTQ
                     TATTFWVSIMTIFKKRYLHLIGAVMVLGVGLSRLYLAVHWPIDVIAGWILGIFFTVVF
                     VKIFDYIDDNKNYILLVVLLIPFIIVAIFLNSPEYFEKFGIIVGFVFGYMVEDRFVKF
                     NTDNNNKKINFSNKNKGSKNIIFSRICRFLVGIVTIGMLYIGIKLFISMLIVTLNISD
                     STMSIIFMNFIKNTVVVFYGIAGAPALFKLLKLN"
     gene            10263..11489
                     /locus_tag="PC494_002841"
     CDS             10263..11489
                     /locus_tag="PC494_002841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HDF3913328.1"
                     /translation="MKKVVIIGGGPAGMIAASTACEKGYDVTLIEKNHKLGKKLAITG
                     KGRCNITNACEIEELIENVPTNGKFLYSAFYTFTNDDVISMFNNLGVKTKTERGKRVF
                     PESDKAFDIVNALERQLKSKKVNILLNSKVEKIISKNNKIEKVILNDKKEIKCDSVVV
                     ATGGLSYPLTGSTGDGYKFAISQGHTIIDTKPSLIGIEVQESFTKDLEKLSLRNVEIR
                     VFNSKQKKVYSDFGELEFTKFGLDGPIIKSASCRMKDTRKENYTILLDLKPALDEEKL
                     DKRVQKDFQKYTNKKFEKALDDLLPKKLIPIIINLSEINPNTVVHQISREQRKNLVHL
                     LKNLKFTVKRYRPIEEAIITSGGVKVNEINSSTMESKLVEGLFFAGEVIDIDAYTGGF
                     NLQIAFSTGYLAGFNC"
     gene            11573..11794
                     /locus_tag="PC494_002842"
     CDS             11573..11794
                     /locus_tag="PC494_002842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000002841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta-type small acid-soluble spore
                     protein"
                     /protein_id="HDF3913329.1"
                     /translation="MASNNNNNRTVVPGAKEALNQMKLEIANELGMSNYQQVDKGNLT
                     ARENGYVGGYMTKKLVEMAEQQMAGKSNR"
     gene            11983..12153
                     /locus_tag="PC494_002843"
     CDS             11983..12153
                     /locus_tag="PC494_002843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3913330.1"
                     /translation="MSSVNFEDLKNKFINSDLDEKIRIYTTTEGLSVEQFKELLKYYP
                     IQHLSKLEKALG"
     gene            complement(12246..12707)
                     /locus_tag="PC494_002844"
     CDS             complement(12246..12707)
                     /locus_tag="PC494_002844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3913331.1"
                     /translation="MQIEQLDLETRNKIYCYTKKILRKYQKGITSGKLTADKFADNIL
                     SQDFISSILNEKIVNETNFKISYRNYIETLINIQNENLSNLRKKSTKTAKCFNISQIT
                     QLKNLLSNTGYNLLIPYKYLTARDIEGIVTLINTGSIELGNERIYNYISKA"
     gene            12890..13357
                     /locus_tag="PC494_002845"
     CDS             12890..13357
                     /locus_tag="PC494_002845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3913332.1"
                     /translation="MKMLNGIIKLFYSEIVKTKINNLDSSGYSLRDECKEIRNITLKI
                     DSVFFKLLKLAFGSILLMVAFNLNMVLGIGVFLVGVVYILYKRNMEEQVKEHINNVKN
                     NIDISKITFMDEKGRTGLNALITLLLIGLLTGFNWILVASFVVVFVFTIKNVC"
     gene            13400..15163
                     /locus_tag="PC494_002846"
     CDS             13400..15163
                     /locus_tag="PC494_002846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpoIIE family protein phosphatase"
                     /protein_id="HDF3913333.1"
                     /translation="MTNGSYKMKNLVEISAMVTESTDFFNIKDDIIEKMLEVVHPTKA
                     CVNLFYKNDSKYAYLVCSQTLEYVPQIFPINSLKGAKIDFDTYPEYIHEAVNEKKIIY
                     VENVFEDSRAEGERDLAKAEGYIGRIVFPFIINNVVVGFMTCFLKEDDYITEQDIDFI
                     SSVASLLSLSIEITNKNNNVQILIDKLRGSISAINEATKKLYLNKSIDGFLENLSKQA
                     CNITNSKEALIIINSHHNKDAIVSCYNVEQKKKTNLYPMIDMFLKKESLGGYLNNLKP
                     CSKKGINLESYIYYKLQDKNDTIGCIVCANSKNYTSDDLNILSILSKQVSVGMQLYEH
                     NEKEVKHKVLENELNILNKQQQLIMDKGKMDCNDEKELYFYHKPARVVGGDFYYATKV
                     DDEHIVYIVADVMGHGMVSNYVVAMIKGAFKVLCNQYNTPREIMTNLNRMLYDEFDKM
                     GVFTTCLIGIIDTKENMITVSNAGHYSPVVVKKDGTIENNLNCKKGIPIGIMEDATYE
                     NNTLSMEDYAMVCMYTDGILEIKNSSKEEYGINRLENFLKENFRLNQQLIVENLKLDL
                     KNFSSKDNYDDDILIVMLKDR"
     gene            15171..15779
                     /locus_tag="PC494_002847"
     CDS             15171..15779
                     /locus_tag="PC494_002847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HDF3913334.1"
                     /translation="MDSNDKKGLKSPEIIIINGSPRINKNCSFIANEVKAMLEECGLS
                     CKIFNIYNMDIEYCTACGFCEKTGYCKFNDDMKPLYKMFDDSKGTIVISPVHFDSISA
                     KLKTVVDRTQAIYASKYVLNKPSIDRSKKRIGMYIAVGGSKSYDSQFKGGQIVMDFFF
                     KSINTKLLHNIYLNNTDDVSYIDNQEFKDIIYKNLKIYIDSI"
     gene            15851..16420
                     /locus_tag="PC494_002848"
     CDS             15851..16420
                     /locus_tag="PC494_002848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate propanoyltransferase"
                     /protein_id="HDF3913335.1"
                     /translation="MKLPIALSNKHVHLSQADIDVLFGAGHELTKFKPLSQPGQYACE
                     EKVDLVGPKGTLKGVRVLGPARAHTQVEISLADGFPLGVKAPIKESGDIAGTPGVKLV
                     GPAGEVEMKEGVIVASRHIHMSNEDAAKFGVTDKQIVKVKTSGPRALVFENVLVRASD
                     SFNLEMHVDMEEGNAAGVKNGDLVELIVD"
BASE COUNT         6501 a         1682 c         2927 g         5500 t
ORIGIN      
        1 taattataag ctatttaatc actggaataa atttacaata aaaaaataaa tacaaaggct
       61 ttatcattaa ggtattggca taagttttgc ttattaaaca agtatactaa taaaattcat
      121 ttaaacagga gggagaattt atatgagtaa attagaatca acaacagaaa aagttgaggt
      181 aaaatggtat gggtatgtag cattaatatt gggagcatta tttttttcag gaatatttaa
      241 agatgcacca ggaccattaa aagtattgga ttttaacaat gtattaggtt cttttggaac
      301 attgggaaca attaatgatg gtgtaggtac attagctgca aactttagag gtgatggagg
      361 tactggccct cgagatggat ggctatatgc attgacatta ataccatcag ttatgtttgc
      421 acttggagta gttagagtta tagaccactt agatggaatg aaggcagctc aaaagcttct
      481 tagtccacta ttaaagccat tattagggtt acctggattt gcaggactaa ctttgatagc
      541 tagtttacag tctacagatg cagctgcatc tatgactaaa gaacttaaag atgatgggta
      601 tatagatgaa aaacaaaaag ctgtattttg tgcatttcaa ttttcaggtg cgtctgcaat
      661 tacgaatttc tttgcttctg gagcagcact atttccattt ataggagatg taccaatatt
      721 tataccactt gctttaatat taattatgaa gtttgttggg gcgaacttac ttagattata
      781 tttaaataaa tttgacaagg gggaagctta acatgagtga ggtagcaaaa aaagaagtaa
      841 aagttaaaaa aggaaatgtg atagatgcgt ttattggagg agctagaaat ggattccaaa
      901 taagtacaaa ttcaatggct ccaaatgtca tcttcggttt tgctataatt tctgtgttca
      961 atttaacagg tcttttggat gtaataggga caatatttac acctgtaatg agtatctttg
     1021 gacttccagg tgttgcagca acagctataa tgacaatatt tatatcaatg ggaggagcat
     1081 ctggagtaat cgcaggttta tttacagcag gtcaaataag tcaagcacat gttgcaattc
     1141 tattgccaat gttattgctt tcaggagcgc agatacaatt tatggggaga cttttaggaa
     1201 cagctgagtt aaaaactaaa tattatccac atatgtttgt tatagcaact ttaaatggtt
     1261 gtattgcaat gcttataatg aattatttcg tagtataggt aattataata aagatttaat
     1321 ataaatggaa agtttaaatt ttaaggagga gctagattat ggaaactaac aaagactata
     1381 ttgagtatgt acataaagtg tatgattatc tacacactat accagaaaaa ggatttgaag
     1441 aatataagac atcagagttt gttttaaaag agcttgaaaa aatggggttt gaaaatatta
     1501 ataaaggaat tgcaggaact ggtattatag taactataga ttctaaaaaa gaaggaccag
     1561 tatttgctat aagagcagat atggatgcat tggaatttat catagatgga gaaaagaaaa
     1621 tgatacatgc ttgtggtcat gatggtcata cttctatgct tttaacagct gcaaagttaa
     1681 taaaagagag aaatttagta aaaagaggta agttaaaaat actttttcaa ccaggtgaag
     1741 aaaaattata tggagcatta agagtaattg attctggttt gttggatgat gtagaagaaa
     1801 tggtagggat gcatttaaga cctggacaag attgtaggtt gggaaaggcg atacctgcaa
     1861 tgtaccattg tgctagctgt ataatggaat ttacgattaa aggtatcact tgtcatggtt
     1921 ctaaaccaca tttaggagta aatgcagtag atgctgtctg tttagcagtg aatgcaataa
     1981 atgcaataag agtaaatcca gctataccaa attctataaa agtaacaaat atatcagtta
     2041 agggagaaac ttataataat ataccagatg aagcatttat ggctttagat ataagggcag
     2101 aaagtaatga tataatagaa gaattaaaag aaaaagcaat acatgctgta aaaactgctg
     2161 taagttctat aaatgcagaa gctgtactaa tttccaaaga tggagtacca gcagcagaat
     2221 ttgatgaaga acttgtaaac ttggctgaag aaactataaa agatgtattg ggagctgatg
     2281 catctatagg tatatttaaa aattctggtg gagaagattt ccattattat acacaaaaac
     2341 taaaatgtaa aactacatat attggattag gagctgatgc tacaccagga tttcataatc
     2401 caaatgtaac atttgatacg aaagctttag aatatggtgt agatatatgg tgtagattgg
     2461 ttgaaaagag attgggataa catccaaact aataattcta catttaaaat tataattata
     2521 gaagttatag aaaaagattg cttatgttaa ttagaaaata attaatatga gcaatcttat
     2581 tttgatataa tgaaactgat tttggaatat tgaaaaaata tgatggaaaa gtaattatat
     2641 tttaaatcta ttggacaaaa aagtgatatt attataatat taagaattgt aaaataatac
     2701 caaagtgcat ctagtaatag acttaacaat tataaaaatt ttattcttag gagggaaaaa
     2761 atgagtaagt ataattttga cagagtaata gatagagtag gaacagattg tgtaaaatgg
     2821 gattttagaa ctaattgttc aacaaaagca caaaaagatg gtttgccttt ttggattgct
     2881 gatatggatt ttgaatgtgc agaaccaata atagaagcat tacgtaaaaa agttgaacat
     2941 aaaatatttg gatatagttc aaatgatagt gataaatact ttaatgcagt ttgtgattgg
     3001 tataaaagga gatttaactg ggaaataaat agaaaagata ttatttttag tcctggtgtt
     3061 gtacctgctg ttgctatttt agtaagaata ttaactaatt ctaatgaagg tgtaatagtc
     3121 caaaaaccag tgtattaccc atttgaagct aagataaaga gcaataatag ggatgttgta
     3181 aacaatcctc tgatatatga gaatggtact tataggatgg attatgatga tttagaagaa
     3241 aaagctaagt gtagcaacaa taaagtactg atactttgta gtcctcacaa ccctgttgga
     3301 agagtttgga gagaagatga attaaaaaag gttgtagaaa tatgtaaaaa atatgaccta
     3361 tggataatag ctgatgagat acattctgat ttaattagaa aaggatttaa acatactcct
     3421 ttacagtcat tatgcccaga gtacaaggat aaaatagtta catgtatagc tccaagtaaa
     3481 acatttaatc tggcaggaat gcagttgtct aatataatag tgaataatga tgaactaaaa
     3541 aagaaatatc aagaagaggt tacagctgtt ggagttgcaa cttcaccaaa tccctttgct
     3601 attgtagcta caatagcagc atataatgaa agtgaagact ggcttaatga attaaatgat
     3661 tacttagata ataatataca atttattgat gaatacttaa aagaaaacct accaaaagta
     3721 aaacttgttt atccagaagg aacatatcta gcatggttag attttactgc ttatggatta
     3781 aatgaagtag aacttgaaga tttaatgttt aaaaaagcta atgtattatt tgatgaaggt
     3841 tatatatttg gaaaagaagg aataggattt gaaagaataa atgtagcttg tccacagtct
     3901 ttattaaaag aatgtatgga cagattaaag actatatttg aaaatttata aagtataggt
     3961 aaaaatttat aaagtgttta aaaataaaaa aataataaac ttgacaaatt ttaactaatc
     4021 acttatcata ctattatgaa taaatagaaa acataagaga gctaaatttt attgaattaa
     4081 actcttaaag actttgaaag gaagagtagt tatagaatgt aattaaagcg agttggtgat
     4141 ggtgtgagac caatatgaag tctataatga agaacatcct ggagttgcta accgaaattt
     4201 taaaagagta ggcttagtcg gaaccaaacc gttatcatat tggggtgtat cgagtaatat
     4261 ctgtacattg tgagctgggt ttgaatttat ttcaaactaa tcagggtggt accgcggaaa
     4321 agcaaccttt cgtccctttt atatagggat gaagggtttt tttaatggaa aaatatataa
     4381 atatagggag tgaatgatat gagcacaata ataccaaagg attataaaag tagtttgaac
     4441 gtaattgata cacaaatagc tataaaaaaa ttaaaagatt tttttgaaat gagactaagt
     4501 aatgaattaa atcttataag agtttcttct ccgttatttg tattgccaga aacaggtgca
     4561 aatgataatt taaatggaga aaaggctgta agctttgata taccatttat gaataaaaat
     4621 gcagaaattg ttcaatcact tgcaaaatgg aaaagattag cccttaaaaa atatgggttt
     4681 gaagttggta gtggtttata tacagatatg aatgcaataa gaaaaaatga agaattagac
     4741 aatatacatt ctctttatgt agaccaatgg gattgggaat tggttataga taaaagtagt
     4801 agaaatgaaa agactctaaa agatgttgta aaaagattgt atggagtatt taaagatact
     4861 gaaatttttg tatgtagtat gtatgaaggt ataaaagaaa tattaccaga agaaataact
     4921 tttataacat cacaagagtt agaagatatg tatccagaat tatcaccaaa ggaaagagaa
     4981 gataaaattg taaaagagaa gaaagcagta tttataactc aaataggaaa aacattaata
     5041 tcaggagaaa aacatgatgg aagaagccct gattatgatg attgggaatt gaatggggat
     5101 atattatttt acaatcctgt tttagattca gcattagaat tatcttcaat gggaattaga
     5161 gttgatgaag aatctcttga tagacaattg aaacttgctg gatgtgaaga gagaaaagag
     5221 tttgactatc ataagatgct tttaaatggc gaacttccgt atacaattgg tggaggaatt
     5281 ggtcagtcaa gaatatgtat gtatttctta caaaaagctc atataggaga agtacaagtt
     5341 ggagtatggc cacaggatat gattcaaaat tgtagtagtg caggaattga attattataa
     5401 tttaaatata aactaattga taaaatttat atctaatatg ttcatcaaat taattatatc
     5461 ggttataatg tagaataacc tataattata agaggtgata aatatggagt ttttaaaaat
     5521 aatcattaat atagttttag atattttaaa aaaaattttg gtcagattta aaaatgctaa
     5581 atttggtttg gtttttgtat ttgatttact taaactacct gattttatga cagataaaag
     5641 aatcaatata gttgataaaa taaaggtaat ttctgtatta atttttacta tatcctactt
     5701 tgtatctggg gttgatataa ttccagagat gattgcaggg gcatttggtt ttatagatga
     5761 tgctatagtt ttaatttgga gtataggtat agtgaatgaa gaaattaata agtatagagt
     5821 tatcgcaaaa aaagataaac attcaaatat aattgaaaat gtagaatttt ctataaaaga
     5881 tgaagaagaa taacaattta tatatgttat tctttttttt attaacaaaa aatggttaaa
     5941 ttgttgacgg agaggtaaaa ctctattatc ataataagtg gatatccaat atttaactaa
     6001 gtattcaatg tgcaagaatg cttaatttaa aaaagttatg gagggtaaat attatgaaga
     6061 aaaaaatagg tttagtgccc aaactaatca tcggtatcat agtcggtatt ttaatcggaa
     6121 gttatgcacc agaaataata gtacaaatat tagtaacagt tagtacttta ttctcagcat
     6181 tcctaaaatt tgttatacca tttataatta taggttttgt aacagcaggt atagctgatt
     6241 tagcaacagg tgcaggaaag ttattgggga taactacggg aatagcatat ggttctacct
     6301 taatagcagg attattatca tttgcagtat ctacattaat cttcccaaat tttattgatg
     6361 caagtgttgc aagtcaaatt ggagacccag aggcaggaat gttagctcca atattcacaa
     6421 ttccattaga gcctatggta gatgtaacag ctgcaatcgt atttgcattt gtaatgggac
     6481 ttggaatatc agctttaaga aatcatggaa aaggagagac tttatttaat ttcttccaag
     6541 aatttcaagg aatcgtaacg aaaacgttgt caacagtgat tataccttta ttacctttat
     6601 acatagcagg aacttttgca aatataacta tagcagggga agtatggaca atattagggg
     6661 tattctggaa agtatactta gtagtaatac ctttacattt tgtatatatg gcatgtcaat
     6721 tcacagcagc aggtgtattt tcaggaaaaa atccagtaag aatgttaaaa aatcaagtac
     6781 ctggatattt aacagctata ggaactcaat cttcagcagc aactatacca gttaatgttg
     6841 gttgtgcaga aaaaaatgga gtaagtaagc aaataagaga atttgttgta cctctttgtg
     6901 caacaataca tttatcaggt agtatgatat caataacagg atttacaact gcagttttaa
     6961 tgatgaatgg tatgccacat ggaataggtg tattattccc ttatattgca atgttaggta
     7021 tagcaatggt tgcagcacca ggagcaccag gtggggctat aatgagtgca cttcctttcc
     7081 taccaatggt tggaatacca tcagatggtg ggcttgcaag tttaatgata gctttatact
     7141 taactcaaga cagttttggt acagcatgta atgtatcagg agataatgca atagcagtag
     7201 tagtagataa aataaatgat ggaatgagta aaaaaggaaa taaagaagag caaagtgctt
     7261 agttttttaa taatcaaaaa tgagttatct caaatagaga tagctcattt tttatggtat
     7321 aaaaaattat aaaataaagt gattttttta tttaaaaatt gctttaagag atgatattaa
     7381 taatttattt tcattaggtt ttaatataca tactctaaag aaatactcat ctagaccttc
     7441 aaatgaacaa caatctctta ttattatttt ttgtggaagc aattgttctc gaagagattt
     7501 agcagtcaat tcctttgtct tgattttaca caatatgaaa ttgcctttag tattgtatat
     7561 atctaagctt tttatattct taagctcttt aagcaggtaa tctctttcag tgttcattaa
     7621 ggaaatagta tttgatataa aatctaaatc actaaacatg atttcaccca ttttagaagc
     7681 tattatgttt atattccata aatctagatt tttatttatt tcatttttga cattagtgtt
     7741 agatataaga ccatatccaa gccttattcc aggcgttgaa aaaaattttg atgtacctct
     7801 tataacgaat aaattagaat aatcatcaac taattgagta caagagtatg tatctgtatc
     7861 agtaaactct acataagtct catcaatcat taaaaatgag tctgtatttt ttaaaatttc
     7921 tctcacttct actttagtaa atgcaaatcc agttggatta ctaggattac agattactac
     7981 caaatcataa tctttagcat tgatagtttt tataagattt tctaaattta tatgaaaatt
     8041 atcttcttct tttgcaaagt atttttctat agaacaatta attttagata actctttttc
     8101 atactctgaa taggctggag agagtaaaag agcctgttta gggttaattg tatgtataaa
     8161 tgatgaaatt agttctgtag ctccactgcc aagtactata ttatctatag aacatttgca
     8221 gtaattggat atagaagttt ttaagtctat gtaatcaggg tcaggataca tagataccat
     8281 atctatattg tttacaatgt attgtttggc taaacttgat gtaccaaaag gatttatatt
     8341 tgagctaaaa tccataaatt cttcctttga aaagccatac ttactagata aactatataa
     8401 attagctcca tggtttgtgc tcataaaagt acctccaaaa ataaaattat ataatcgata
     8461 aaaataactg attaatatat gtacatatag attataatac aaaggaatcg ttattccaaa
     8521 tttttaatgg aaaaagcaaa aaagtatgga taagctgtta atttaggttt aaaaatgatg
     8581 aaaaagattt taattgatat tttggtatgc tataatatat aagttaatag aaggaaagcg
     8641 ggaggataca aaatgtacaa agttacagga aaaatgttga cagaagaaca aataaaagaa
     8701 aaagtttatg aattaggaaa aaagatagaa gaagacttta aaggcgaaga tttactagtg
     8761 gtaggtatac ttaaaggagc tagtgtattt gtttcagatt taataagatg tatagatttg
     8821 gatgtaaata tagattttat gagtgttaca agttatggaa actcaacaga gtcttctgga
     8881 acagttaaaa tattaaaaga tttagatgta gatattgaag gaaagaatgt gttgattgta
     8941 gaggatataa tagattctgg tttaacatta agtaatctag ttgcagcttt aaaaactaga
     9001 aatccaaaat ctttaaaact atgtactcta cttgacaaac ctcagagaag aaaagctaat
     9061 atacctgtag actatgttgg atttgttata gaagacaaat ttattgttgg ttatggaata
     9121 gactatgctg aaaagtatag aaatttacct tatataggta tagttgagga tgtagaatag
     9181 atttaaatgt gaatcaaaag cactaatttc taagggagtt agtgcttttt agttaattat
     9241 ataaaatttt agtaaaggag acatctatat ggatattcag ttaaatatat tattattttt
     9301 ccaaaattta agaaatccaa ttttgaactt tatatttctt gtctttacaa taagcacaga
     9361 agcaccgtta ttaatattaa ttacaacaat tatatactgg tgtataaata aaaaatgtgg
     9421 acagaaaata ctgtttgcta taattggaaa ttttgttgta aatttaggca tcaaagagtt
     9481 tgtaaaagct cccagaccaa taggaataaa aggtcttgaa tcattgagag tttctactgc
     9541 tggtggttat tcttttccaa gtgctcatac tcaaactgca acaacatttt gggttagtat
     9601 tatgactata tttaaaaaga gatatcttca tttaataggt gcagttatgg ttttaggagt
     9661 aggattgtct aggctgtatt tagctgttca ttggccaata gatgtgatag cgggttggat
     9721 attaggaata ttttttacag ttgtatttgt aaaaatattt gactatattg atgataataa
     9781 aaattatatt ttacttgtag ttttacttat accatttata atagtggcta tatttctaaa
     9841 tagccctgaa tattttgaaa aatttggtat aatagtagga tttgtatttg gatatatggt
     9901 tgaggataga tttgttaaat ttaatacaga taataataac aaaaaaataa attttagtaa
     9961 taaaaataag gggagtaaaa atataatttt ttcaagaata tgtaggtttt tggttgggat
    10021 agtaacaata ggaatgttat atattggcat taagttgttt atttcaatgt taatagtcac
    10081 tttaaatata agtgactcta ctatgagtat aatttttatg aattttatta agaatacagt
    10141 agttgttttt tatggaatag caggagctcc agcattattt aaacttttaa aattaaattg
    10201 attttaaggt atagagtcaa tagtttaaat taaaaaaatt aagggtagaa aagagtgatt
    10261 atttgaagaa ggtagtaata ataggtggtg gaccagcagg gatgatagcc gcatcaactg
    10321 catgtgagaa aggctatgat gtaacattaa ttgagaaaaa tcataaatta ggaaaaaaac
    10381 ttgcaataac aggaaaaggt agatgtaata ttactaacgc ttgtgaaata gaggaattaa
    10441 tagaaaatgt acctacaaat ggaaaatttc tttatagtgc tttttatact tttacaaatg
    10501 atgatgtaat aagtatgttt aataatcttg gagtaaagac taaaacagaa agaggaaaaa
    10561 gggtttttcc agagagtgat aaagcatttg atattgtaaa tgctcttgaa agacaactta
    10621 aaagtaagaa agtaaatata ttattaaatt cgaaagtaga aaaaataata tctaaaaata
    10681 ataaaattga aaaagtaatt ttaaacgata aaaaagaaat taagtgtgat tcagttgtag
    10741 tagcaactgg tggattaagt tatccactta ctggttctac tggtgatgga tataaatttg
    10801 caatttcaca ggggcacaca attatagata caaaaccatc tttaattggt atagaagtac
    10861 aagaaagttt tacaaaagat ttagaaaaat tatcattgag aaatgttgaa ataagggtgt
    10921 ttaatagcaa acaaaagaaa gtttatagtg attttggaga acttgaattt actaaatttg
    10981 gtttagatgg acctataatc aagtctgcaa gttgtagaat gaaagataca aggaaagaaa
    11041 attacactat attattagat ttaaaacctg cattagatga ggaaaaattg gataaaagag
    11101 ttcaaaaaga ttttcagaag tatacaaata aaaaatttga aaaagcatta gatgatttac
    11161 ttccaaaaaa actaatacct ataataataa acttaagtga aattaatcca aatacggttg
    11221 ttcaccaaat ttctagagag cagagaaaaa acttagtcca tttattaaaa aatttaaagt
    11281 ttacagtaaa gagatacaga cctattgaag aagctataat aacttctggt ggtgtaaaag
    11341 taaacgaaat aaattcaagt acaatggaat caaaattagt agaaggttta ttttttgctg
    11401 gagaagtaat agatatagat gcatatacag gtggattcaa tttgcaaata gctttttcta
    11461 ctggatattt ggcaggtttt aattgctaaa aattacctga attaaaaatg tttaaaatca
    11521 cataatatta tcagcaacac aaaataaatt aaacagaagg aaggtaatca acatggcaag
    11581 taacaataac aacaacagaa cagtagtacc aggagcaaaa gaggctttaa accaaatgaa
    11641 attagaaata gctaatgaac ttggtatgag taattatcaa caagttgata aaggaaacct
    11701 tactgcaaga gaaaatggtt atgtaggtgg atacatgact aaaaaattag ttgaaatggc
    11761 tgaacaacaa atggctggaa aaagcaacag atagttataa ataattattt ataactattg
    11821 gctattagtt tagctagagc tatctcaaat atagaaagta atttctaaat tgagatagct
    11881 tttttttatt aaattattaa atagatatat ttttatgtaa taaattttat gtatttggat
    11941 aaaataatac aaatgaatat gttacataag gagtgatgta aaatgagtag tgtaaatttt
    12001 gaggatttaa aaaacaaatt tattaatagt gacttagatg aaaaaataag aatatataca
    12061 acaacagaag gtttatcagt agaacaattt aaagagctac taaaatatta tccaatacaa
    12121 catttatcta aactagaaaa agcacttgga tagcagtatt taatccaaaa ttaaaaaggc
    12181 aatttattta atattaaaaa tattttttat taaataaatt gcctttttat aataggttta
    12241 aattattatg cttttgatat ataattatag attctctcat ttccaagttc aatagaccca
    12301 gtattaataa gagtaactat tccttctata tctctagcag ttaagtattt atatggaatt
    12361 aataaattat aaccagtatt acttagtaag ttttttaatt gggttatttg agagatattg
    12421 aaacattttg cagttttagt agattttttt cttaagttag ataaattttc attttgaata
    12481 tttattaaag tttctatata gtttctataa gatatcttaa agtttgtctc attgactatt
    12541 ttttcattaa gtatactact gataaaatct tgagacaata tattatctgc aaatttatct
    12601 gctgttaatt ttccagatgt tatgcctttt tgatattttc taagaatttt tttagtatag
    12661 cagtatattt tatttctcgt ttctaaatcg agttgttcta tttgcacaaa accacttcct
    12721 tctaattata aaaatattta ttaaaaatct atacttaact aataaagctt caataactta
    12781 tttacaataa atactaaatc ataaaatatt tgttattttt tattattacc aagtataaaa
    12841 aatattataa ttgtaaaact tacaaatata tgtaaaatat ttaggagtga tgaaaatgtt
    12901 aaatgggata ataaagcttt tttattctga aattgtaaaa acaaagatta ataacttaga
    12961 ttcaagtgga tattctttaa gagatgaatg taaagaaatc agaaatataa ctctaaagat
    13021 agatagtgta ttttttaagc ttttaaagtt agcttttggt tcaatattgc ttatggtagc
    13081 ttttaattta aacatggttt taggtatagg agtgttttta gttggtgtag tttatatact
    13141 atataaaaga aatatggaag aacaagtaaa agaacatata aataatgtga aaaataatat
    13201 cgacatctct aaaataactt ttatggatga aaaagggaga acaggtctaa atgcattaat
    13261 tacattactt cttataggat tattgacagg atttaactgg atattagttg ctagttttgt
    13321 cgttgttttt gtttttacta taaagaatgt atgttaaaat actaataaat agtttaatat
    13381 atagggggag aaattgagta tgactaatgg cagttataaa atgaagaatt tagtggaaat
    13441 atccgctatg gtgactgaat ctacagattt ttttaatata aaagatgaca taatagaaaa
    13501 aatgttagaa gttgttcacc ctacaaaggc atgtgtgaat ctattttata aaaatgattc
    13561 taaatatgcc tacttagtat gttcgcaaac cttagaatat gtacctcaaa tttttccaat
    13621 aaatagtctt aaaggtgcaa aaattgattt tgacacatat ccagagtata tacatgaggc
    13681 tgtaaatgaa aaaaagataa tatatgtgga aaatgtattt gaagattcta gagcagaagg
    13741 tgaacgagat ttagcaaaag ctgaaggtta tattgggaga atagtttttc cttttataat
    13801 aaataacgta gttgttggat ttatgacttg ttttttaaaa gaggatgatt atataacaga
    13861 acaagatata gattttatat catctgttgc atcactctta agtttatcaa tagaaataac
    13921 taataaaaat aataatgtac aaattttaat tgataaacta agaggctcaa taagtgccat
    13981 aaatgaagct actaaaaaac tataccttaa taagagtatt gatggctttt tggaaaattt
    14041 aagtaaacaa gcgtgtaata ttactaatag taaagaagct ttaataatta taaatagtca
    14101 tcataataag gatgctatag ttagttgtta taatgttgag caaaaaaaga aaacaaattt
    14161 atatcctatg attgatatgt ttttaaagaa agagtcattg ggggggtatc taaataattt
    14221 aaaaccatgc tcaaaaaagg gaataaattt ggaaagttat atatattaca aacttcagga
    14281 taaaaatgat actataggat gtatagtttg tgcaaatagc aaaaactata ctagtgatga
    14341 tttaaatatt cttagtatat tgtccaaaca agtttctgtt ggtatgcaat tatatgaaca
    14401 taatgaaaag gaagtaaaac acaaagttct tgaaaacgag ttgaacatat taaataaaca
    14461 acaacagctt attatggata aaggtaaaat ggattgtaat gatgagaaag aactttattt
    14521 ttaccataaa ccagcaaggg tagtaggtgg agatttttat tatgctacaa aagtggatga
    14581 tgaacatata gtttatattg ttgctgatgt aatgggacat ggaatggtat caaattatgt
    14641 tgttgcaatg ataaaaggtg cttttaaagt attatgtaat caatacaata caccaagaga
    14701 aataatgaca aatttaaata ggatgttata tgatgaattt gacaagatgg gagtatttac
    14761 aacttgtttg ataggtatta tagatactaa agaaaatatg attactgtgt ctaatgcagg
    14821 tcactatagt cctgtagttg taaagaaaga tggcacaata gaaaataatt taaattgtaa
    14881 aaagggcata cctattggaa taatggaaga tgctacttat gaaaataata ctctttcaat
    14941 ggaagattat gcaatggtat gtatgtacac tgatggaatt ttagagataa aaaattcatc
    15001 aaaagaagag tatggtataa accgattaga aaactttcta aaagaaaatt ttagattaaa
    15061 tcaacagtta atagtagaaa atctaaaatt ggatttaaag aacttctcat caaaagataa
    15121 ttatgatgat gatattttaa tagttatgtt aaaggatagg tagattgatt atggattcaa
    15181 acgataaaaa aggacttaaa agtccagaga ttataataat aaatggaagt ccaagaatta
    15241 ataaaaattg cagttttata gcaaatgaag taaaagctat gctagaagag tgtggattaa
    15301 gttgtaaaat atttaatatc tacaatatgg atattgaata ttgcacagca tgtggatttt
    15361 gtgaaaaaac agggtattgc aagtttaatg atgatatgaa gccattatat aaaatgtttg
    15421 atgattcaaa aggaactata gtaataagtc ctgtacattt tgattcaata tcagctaaat
    15481 taaagactgt tgttgataga actcaagcta tatatgcaag taaatatgta ttaaataaac
    15541 cttcaattga tagaagtaag aaacggatag gaatgtatat tgcagtggga gggagtaaat
    15601 catatgattc acagtttaaa ggtggacaga ttgttatgga ttttttcttt aagagtataa
    15661 atactaaact tttacacaat atatatttaa acaatacaga tgatgtatct tatatagata
    15721 atcaagaatt taaagatata atatataaaa atttaaagat atatattgat tcaatataat
    15781 ttgattttgt aggtaatatt atgtataatt gtattgcaat aatttaaata attaaaagga
    15841 gggaatttca atgaaattac caatagcatt atctaataaa catgttcatt tgagtcaagc
    15901 tgatatagac gtattatttg gagcaggtca tgagttaact aaatttaaac cattatctca
    15961 accagggcaa tatgcctgtg aagaaaaagt ggatttagta ggaccaaaag gaactttaaa
    16021 aggagttaga gtactaggac cagctagagc tcatactcaa gttgaaatat ctttagcaga
    16081 tggtttccca ttaggagtaa aagcaccaat aaaagaatct ggtgatatag ctggaactcc
    16141 aggtgttaaa ttagtaggac ctgctggaga agttgaaatg aaagaaggag ttatagttgc
    16201 ttctagacat atacatatga gcaatgaaga tgctgctaaa tttggtgtaa ctgataagca
    16261 aatagtaaaa gttaaaacat ctggaccaag agcattagta tttgaaaatg tattagtaag
    16321 agctagtgac agctttaatc tagaaatgca tgttgatatg gaagagggaa atgcagcagg
    16381 cgttaaaaat ggagatttag tagaattaat agttgattaa tattataaat agactttatg
    16441 ctagtagata ttttatttgc tagcatattt ttaaatgtaa taaatttcta taggataaat
    16501 ttaatcgatt agattaattt ataaaataaa ggggtattat aaaaaatgta ataaaaactt
    16561 acaaaaatat gatgtaatat ggtaaaatta tatatataaa aatttacata
//
LOCUS       DAMKNB010000078        16597 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.082, whole genome shotgun sequence.
ACCESSION   DAMKNB010000078 DAMKNB010000000
VERSION     DAMKNB010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 16597)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16597)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16597
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.082"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            <1..516
                     /locus_tag="PC494_002849"
     CDS             <1..516
                     /locus_tag="PC494_002849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDF3913336.1"
                     /translation="FISNLKKSLNKLAKLQRELSRKTIGSLNRNKARLKVARLQEHIA
                     NQRNDFLQKLSTKLIKENDIICIEDLQVKNMIRNRKLSRSISDVSWSEFIRQLEYKAN
                     WHGRQIVKVGKFFASSQICNKCGYKNEEVKDLNIREWIYPSCNETHDRDINASINILK
                     EGLRLITIQNK"
     gene            948..1202
                     /locus_tag="PC494_002850"
     CDS             948..1202
                     /locus_tag="PC494_002850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3913337.1"
                     /translation="MENKDIKLTICIFAFVIGIIVLFCCIGLGQFNMDCIIKQNGGSI
                     ATEQYNIYLEQSISQYRNFGSILVLLGGIGILFDKSVRKY"
     gene            1238..1561
                     /locus_tag="PC494_002851"
     CDS             1238..1561
                     /locus_tag="PC494_002851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3913338.1"
                     /translation="MARDVFSVKMTPLEAQKMVEKNLEADLVSVDIYNLENNKSIIVT
                     IFEKYYARSNSDAGLVVICENTTGKTLVKITSTGSAIGLFQIDWGTGNNLIKRVKKIL
                     IDYII"
     gene            1835..1987
                     /locus_tag="PC494_002852"
     CDS             1835..1987
                     /locus_tag="PC494_002852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3913339.1"
                     /translation="MDNFLFNVLASVTASYIVYLISKLIKKVKSHSTAKSDLKIDINF
                     KYHRKK"
     gene            2181..3104
                     /locus_tag="PC494_002853"
     CDS             2181..3104
                     /locus_tag="PC494_002853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SHOCT domain-containing protein"
                     /protein_id="HDF3913340.1"
                     /translation="MVGAFVLPNYAIILSEMSNLWGNFIMWILVPIITIVLLIIAVSS
                     MQYILVMIAFLLIIYSFIEKKIVMGLVSVLFFTYSIYLCATWEDKSLIADNKVETVRA
                     QRETVEREKEMERRRIQEEVDKERYIEKHGMEISENDLKVKLEALVPQEYKGKKYELK
                     VGKFKRYSMYFDLTVQNEKFSNSEECKKFVKEIANDLKKIKISKAYFKFHSKDDGGIY
                     NSVYIDYFRNIQNNVDNVENLEFNEFELKTEEEEKREQEKIEQEKNSYNNYIQNRVVD
                     PLDRIKKLKELLDSGAITQEEYNKKKKELLE"
     repeat_region   3371..4450
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=3371..3399
                     /rpt_unit_seq="gttttagattaactatatggaatgtaaat"
     gene            4605..4793
                     /locus_tag="PC494_002854"
     CDS             4605..4793
                     /locus_tag="PC494_002854"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3913341.1"
                     /translation="MNKIATKSRAEYMKNRRKDKRGFSVLLDKEKLDKFDEVLEEKNL
                     TKKEWLEEKIDEELEQKE"
     gene            4914..5727
                     /locus_tag="PC494_002855"
                     /pseudo
     CDS             4914..5727
                     /locus_tag="PC494_002855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888845.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="toxin Bro"
     gene            5779..5940
                     /locus_tag="PC494_002856"
     CDS             5779..5940
                     /locus_tag="PC494_002856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3913342.1"
                     /translation="MCENLLDNMYIEKRKEEYRIKLLKIRETDIDIYNKLESIVYKLS
                     EKKLEKNNK"
     gene            complement(6269..6733)
                     /locus_tag="PC494_002857"
     CDS             complement(6269..6733)
                     /locus_tag="PC494_002857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3913343.1"
                     /translation="MDFGEVKSELSDKDLKDNEEALNKYKKYYLKVYKYYSEMDSIKS
                     IQDIEIEQSRLKGQLQKNSNPIFALYISIMAVVFSTTINLTFDLSDITNYFIRMIMTL
                     LFIVLLIFLVNKGILPIAIPYRNNIQFYTTALDVLEDMKKKILRERKYKKRR"
     gene            complement(6869..7186)
                     /locus_tag="PC494_002858"
     CDS             complement(6869..7186)
                     /locus_tag="PC494_002858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3913344.1"
                     /translation="MDFGNINLILIGIIVIIGTTIIYLIKPKTAFCSKKYFNKLESIY
                     GNIDKKKTVKLEVLYRYVTGLEYIAIGLFTRRLDITILAIILVAIITTALYYLIRKKY
                     ITI"
     gene            complement(7564..7764)
                     /locus_tag="PC494_002859"
     CDS             complement(7564..7764)
                     /locus_tag="PC494_002859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3913345.1"
                     /translation="MYFKTYILKREVNNKQLEITRSFDLDNLICTATEILEDIEIDLI
                     IIDEKNNVVWRNEKNTPAHENA"
     gene            complement(7783..8196)
                     /locus_tag="PC494_002860"
     CDS             complement(7783..8196)
                     /locus_tag="PC494_002860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3913346.1"
                     /translation="MKVKSKRSFIVGIIVCMLCCASLVIYCILKDKRFLISSFLLIVI
                     AIFNFCNAFSRKGIVEELHDSADERDLYLTMKTSHILVKIMNYTLFTFTFLFIIAYSA
                     WKNQSLLVIAITLCVIEIFLFVAYLLINIFLEKKE"
     gene            complement(8180..8413)
                     /locus_tag="PC494_002861"
     CDS             complement(8180..8413)
                     /locus_tag="PC494_002861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF3913347.1"
                     /translation="MKTKVREFRTNMGLTQQQLADLVHVSNRTIISIEKEQYSPSLML
                     AYRMAQVFGTTIEELCCLKENKEMEDKKHESKE"
     gene            8632..9006
                     /locus_tag="PC494_002862"
     CDS             8632..9006
                     /locus_tag="PC494_002862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HDF3913348.1"
                     /translation="MKISKLPEAELKVMRYICEANKVLTSRELVAAMEEKYEWNESTT
                     FTVLKRLERREFLSTEKIGKLTHYNILVKEKKYLRFETKEFLKNIHKNSISSLMSALH
                     GEDDEVDEDKLSELEEYFKNLK"
     gene            9618..10310
                     /locus_tag="PC494_002863"
     CDS             9618..10310
                     /locus_tag="PC494_002863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF3913349.1"
                     /translation="MYNILVVDDDKEIVDSIEIYLKSEGFKIYKAYDGMKALEIITEN
                     DIHLILMDIMMPKLDGIKATVKIREERNIPIILISAKSEDTDKIIGLNIGADDYITKP
                     FNLLELIARVKSNLRRYVTLGNYEDTCKEILKSGALELNTLTKEVKIDGENIKMTPIE
                     YKIIELLLENKGRVFSIDEIYEKVWNEESFNSENTVAVHIRRIREKIEINPKEPRFLK
                     VVWGVGYKIEKF"
     gene            10506..12566
                     /locus_tag="PC494_002864"
     CDS             10506..12566
                     /locus_tag="PC494_002864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HDF3913350.1"
                     /translation="MEKYRVLKLVSLIIISISFPLTILLVTIGLAEPKYNIQKTSTKS
                     GIFDISDDFYDSNIFDEGTMASLLPKFKLSVGGKLTSKEKGKFQQEGKSIDLSSSDSE
                     YDKIMINEQASEEYLSYLKNIKVYVINTYTGVFYTNTSYASLYDFKQKTKSYCNVEII
                     NKIGKSSYIKTINGEKFELNNLSLELNEVDEGFEAYVSFPEEPTIEDGIVYTNFQIFK
                     QATEKVRLFFVASLSLAIICLLSIILYIKIKGEVLKRNNVFLLIYSKIPMEFNVILVS
                     ISIAILTIYALAVSYHIDVIALVSLSLLIVSNNIFFINVQLSYLENKMCIFKTSIIVR
                     VILWLIKTVREVSNAIKKVSLARKVIVIVIISLALIMVISTRSIGMGLLFSICIFLGF
                     TIYITKRLSYLSYVIEGTERIKKGELDYKIKITGNDNFTSLAENINNIGEGLDRAIEE
                     QVKSERMKSDLITNVSHDLKTPLTSIINYVDLIKKEESIQPEYINDYINVLESKSKRL
                     KLLIEDLFEASRVSSGNIELQISKIDLVQLLRQSIGELEEKLSKNNLYLKLNVPNDKV
                     YIWADGRRMYRVFENLLSNIAKYSLEETRVYIDVYDYGENVKVTMKNISSYELNFDPS
                     EIMERFKRADESRNTEGSGLGLAIARDLVALQGGKFYIEIDGDLFKANLEFQKYEEEI
                     TNME"
     gene            complement(12772..13095)
                     /locus_tag="PC494_002865"
     CDS             complement(12772..13095)
                     /locus_tag="PC494_002865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HDF3913351.1"
                     /translation="MNNNYIFFIIIGMYIVTYLPRVLPMLIFSKKEMPDFLKKIMKFI
                     PVAILTSLTAKDVFFNGDSLYLSIANPKIISFMIVLLVAYKFKSIGISIITGVISIYL
                     FGIIL"
     gene            complement(13088..13789)
                     /locus_tag="PC494_002866"
     CDS             complement(13088..13789)
                     /locus_tag="PC494_002866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HDF3913352.1"
                     /translation="MERTQQLKESFIASIPIFLGYIPIGIVGGILLQKSGLSPFQIAL
                     MVTLVFGGSSQFIAASMISTGASVTSIVLTTFIVNLRHFLMSSNLNMYIKNKSPKFIL
                     PFCHTITDETFAVNYEKFTAGNWSDRNAIYLNFFCLISSVLANFIGAFLGESISIDSS
                     ISGFILTSMFIALIVSQIKNKIYIVVFISSIIISVILYALFKSNLVIIVASILASLIG
                     FFIEESYCKKEESYE"
     gene            complement(14067..15452)
                     /locus_tag="PC494_002867"
     CDS             complement(14067..15452)
                     /locus_tag="PC494_002867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HDF3913353.1"
                     /translation="MPINSFENYPMNWKPKRPSKGQILYKALAEQLEQDINNGFLLPG
                     TKLPPQRELADFLDVNVSTISRAFKICEKKGLISGVTGSGTFVSYDTRSNLFLMSSNN
                     KITFIEMGTMNPDFTLEEMNTLFKHIIKEIGFKTIFQYGQRDGAKWQKEAIAKLIYKA
                     GLETTSDSLLPASGGQNAIVAILAGLFQHGDRIGVDPLTYPGIKTAAKMLGIQLIPIK
                     QEDNEISEEGLLYACKNENIKGLYIIPDYQNPTTHIMSQNGRKMIANIASKYNLIVIE
                     DAIHSLLNETHLNPVASYLPNQTIYITSLSKIIAPSLRLAYISTPKQYREALSSALYN
                     INLSQSYFLTEIAYRMITSGEADKLINARRKSARRRNKIINQYLSGYNLLGNEECIFR
                     WLILPDGIMAEKFEIQALKEGVQVYASERFAVGKEKPISAIRIAVCATESTEELKAGL
                     SVLKRLLEEKK"
     gene            complement(15560..>16597)
                     /locus_tag="PC494_002868"
     CDS             complement(15560..>16597)
                     /locus_tag="PC494_002868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M56 family metallopeptidase"
                     /protein_id="HDF3913354.1"
                     /translation="YKHNIDNYIPYDQGITLDIFMYIWILGIIAISFYYLRTNFKFYN
                     YIENFKKEILEIDITSILDEQAKELSINKKLQIYKVKGIYSPAIIGLTRCKIIIPEKK
                     YNNKELRFIFKHELIHYKRKDNLFKLLISIICIIYWFNPILYLLKKYFHELCELSCDE
                     IVIDKCTTSEIKEYAYIILDTIKYQKSLKYSSFVSQFLNKKNIILKKRLNSMFNQDKK
                     KINLGLKFLLTFIIIGSIFSINSNFKQNEDVEYTIGKINYNKNGETYGTHIIDSNGNS
                     IEPELIQTIGRGKKVGYVKKRDLYDCDNQPKTPEEAVLYTRKRNFNIFKKTIPLYDKE
                     GIKIIGRFEIN"
BASE COUNT         6541 a         1807 c         2506 g         5743 t
ORIGIN      
        1 tttatctcaa atcttaagaa gtcattaaac aaacttgcta aattacaaag agaattatca
       61 agaaaaacaa tcggtagttt aaatagaaat aaagcaagat taaaagttgc aagacttcaa
      121 gaacatatag ctaatcaaag aaatgatttt ctacaaaaac tatctactaa attaataaaa
      181 gagaacgata ttatttgcat agaagattta caagtaaaga atatgattag gaatcgtaaa
      241 ctatctcgct caatttctga tgtgtcatgg tcagagttta ttcgtcaatt agaatacaag
      301 gctaattggc atggtagaca aattgtaaag gtgggtaaat tctttgcaag ttcacaaata
      361 tgcaataaat gtgggtataa aaacgaggaa gtgaaggact taaatataag agaatggatt
      421 tatcctagtt gtaatgaaac tcacgataga gatataaatg caagtataaa tatattaaaa
      481 gaaggattaa gactaataac aattcaaaat aaataacgta tgtaagaacc gtaggaacta
      541 cggggatagc ctgtggagaa ttagtaagac atatgttagt atgcaaaatt ctgtgaagca
      601 ggaaacctgt gactttagtc atgggaggtt caggctagta ttactcatta ttgtattcaa
      661 aagctaaagt ggaaacctag tgaatatatg aatttagaag ttaatgagag agcattagca
      721 gccgactcaa tacttattaa aattgaagat gaagaagaaa caatgaaaga agctgaaaga
      781 gagaaaaaga gaggtagaag aaggtagaat ttaaagttaa aatagttaca ttgctaatat
      841 atgaaaatgt tacaaatttg gaaatagatg gatatatatg ttgtatagta taatgtagat
      901 aatatatcac caagtaaaaa acaacaaata aatctaaatt atgaggggtg gaaaataaag
      961 atattaaact tacaatatgt atatttgctt ttgtaattgg aataatagtg ttattttgct
     1021 gtataggtct aggtcaattt aatatggatt gtattataaa acaaaatggt gggtcaatag
     1081 ctaccgaaca atacaacata tatttagaac aatctatttc acaatataga aattttggtt
     1141 ctatactggt tttactagga ggaataggaa tactgtttga taaaagtgtc agaaaatact
     1201 aaaaaagtat atttttattt aggatgtgat gaatgatatg gcaagagatg tatttagtgt
     1261 aaagatgaca ccactagaag cacagaaaat ggtagaaaaa aatttggaag cagatttagt
     1321 ttctgttgat atttataacc tagaaaataa taagtctata atagttacaa tctttgaaaa
     1381 atattatgca agaagcaata gtgatgcagg tttggtagtg atttgtgaaa atactacagg
     1441 aaaaacactt gttaaaatta cctcaactgg tagtgcaatt ggactatttc agattgattg
     1501 gggaacaggt aataatttga ttaaaagagt aaaaaaaata cttattgatt atattattta
     1561 attattttat gtagatattc ttaggttggt atggaatttg tactaaccta ttaagtaatc
     1621 aataaaacta aataaacata gaaagcactt acaaatatgt aggtgctttt tattgaaaaa
     1681 atagaaaata aaataaaaag taagatatag gaaaaatatg taagaattat atgttataat
     1741 aattgtagca agaagatgta atctacaatt tatagagtgg agttcatgta ttaaaaaatt
     1801 atcctcccaa cgataagaag ggaggtgaat atacatggat aattttttat ttaatgtgtt
     1861 agctagtgta acagctagtt acatagttta tttgattagc aagttaatca aaaaagtaaa
     1921 aagccactct accgcaaaga gtgacttaaa gattgatata aattttaaat atcatcgtaa
     1981 aaaataactt tcagttatag aacttcactc taccgcaaat agattgtagt tcttcttgtt
     2041 tttattatac cacaaattag aaaaaatatt gcatataata ttttttatag tcaataaaaa
     2101 tatgaaattt tttatacaca atgatgatga atctaactag atgaataaat ttaattgtaa
     2161 ataagaaagt acttacttaa atggtaggtg cttttgtttt gccaaattat gctataatat
     2221 tgagtgagat gagtaatttg tgggggaatt ttataatgtg gatattagta ccaataataa
     2281 caatagtatt acttataata gctgtttctt ctatgcaata tattttagtt atgatagctt
     2341 ttttgttgat tatatattct tttatagaaa agaaaatagt tatgggtctt gtgtcagttc
     2401 tttttttcac ttattcaatt tatctttgtg caacttggga agataaatcc ttgatagcag
     2461 ataataaagt tgagactgtt agggcacaaa gagaaactgt agaaagagaa aaagaaatgg
     2521 aaagaagaag aatacaagaa gaagtagaca aagaaagata tattgaaaaa catggaatgg
     2581 aaatatcaga aaatgattta aaagttaagc tagaggcttt agtacctcaa gaatataagg
     2641 ggaagaaata tgaattaaaa gtaggaaaat ttaaaagata tagtatgtat tttgatttaa
     2701 ctgtacaaaa tgaaaaattt agtaattctg aagaatgtaa aaaatttgta aaagaaattg
     2761 ctaatgatct taaaaaaatt aaaataagca aggcgtactt taagtttcat tcaaaagatg
     2821 acggcggtat atataattct gtttatattg attattttag aaacatacaa aataatgtag
     2881 ataatgttga aaatttagaa ttcaatgagt ttgaacttaa aaccgaagaa gaagagaagc
     2941 gagaacaaga gaaaatagaa caagaaaaaa acagttataa taactacatt caaaacagag
     3001 tggttgaccc actagataga ataaagaaac taaaagagtt gctagattca ggagcaatta
     3061 cacaggaaga atataataaa aagaaaaaag aattattaga atagataata tagtaagcac
     3121 ttacaagtat gtaggtgctt ttaaatttac aaagtattcc attttaattt tatagtttag
     3181 attttatgat ataataaaaa tatagaagtt ttgcagtgtg cgatatttgt tacaaagtag
     3241 ggcttaatac ttgaaatcta agatgttgag ggtgcgtgat aagtgttatc aattgcacta
     3301 ttgcccgctc actgcaattt taagagtatt gtatatatgt aggtattgga aatgctaagt
     3361 ttattttggg gttttagatt aactatatgg aatgtaaata ttacatgggt aaaaattttg
     3421 atgattttta tgacagtttt agattaacta tatggaatgt aaattgtata gaattaagaa
     3481 tttttttaat actaattata gttttagatt aactatatgg aatgtaaata ttacatttaa
     3541 tttgcattgc tttgatgact tctttgtttt agattaacta tatggaatgt aaatattttt
     3601 caatatcaat atagaacttt catctttccc gttttagatt aactatatgg aatgtaaatc
     3661 aagatatttt taataaaatt tctgagcgaa ctgtttgttt tagattaact atatggaatg
     3721 taaatgagga gattcagaca gcgactaaaa agactgatat aaagttttag attaactata
     3781 tggaatgtaa ataactttat atctccattt gcatatccat ctgatgaacg ttttagatta
     3841 actatatgga atgtaaatgc gtacaaggtt gagaagctcc gcaatctcaa cgtcgtgttt
     3901 tagattaact atatggaatg taaatatttg aaaggaataa attttaaatg aatgaaagga
     3961 taggttttag attaactata tggaatgtaa atcagccaaa aacttcgaat ttgaactaaa
     4021 atgcgtgggt tttagattaa ctatatggaa tgtaaattct catgactatt gaataaatat
     4081 aataaacaag catacgtttt agattaacta tatggaatgt aaatttagaa tcaaaagcac
     4141 ttaatcctag ttctttcata gttttagatt aactatatgg aatgtaaata gctttttagc
     4201 ttcgtctact actttataag caaagcgttt tagattaact atatggaatg taaatgatga
     4261 acaataaaac aatcatctaa agacgaagaa agttttagat taactatatg gaatgtaaat
     4321 gttcctgttg tgttttttac taatcccatt ttatatgttt tagattaact atatggaatg
     4381 taaattgctg tgatttcact aataaaacaa ttaataattg tgttttagat taattatgtg
     4441 gattcaaaat taaataaaca aagaaagcac ttacaaatat gtaggtgctt ttattctgtt
     4501 caaaattggt cggttgggta aaataattag aaaaaattag taaaaacctc ttttctgtaa
     4561 ctcgttacaa tattattatt aatgtaacga gttacagaaa agaggtgaat aaaatagcaa
     4621 ctaaaagtag ggcagagtat atgaaaaatc gtcgaaaaga taaaagaggt tttagtgtac
     4681 ttttagacaa agaaaagtta gataaatttg atgaagtatt agaggaaaag aatctaacca
     4741 agaaagaatg gctagaagaa aaaatcgacg aggaactgga acaaaaggaa taaaaaataa
     4801 gggtcactcc caccgaccaa agtttgagta acccctatga cgtatactat catatatcaa
     4861 ttatagtata tgtcattcct taaaaaaaat caattattaa ggagtgtaat attatgaaaa
     4921 atgaattaat gatgtttgaa ggaaaagaga ttgaagtatt tgaatttgaa ggaagaattt
     4981 tattcaactc aaaagatgta gcaaactgtt tagacataaa aaatgttaat gagaatataa
     5041 gacttatgaa taaaaagcaa gttgtaaagt taagaaattc ggatatcagt aatactgaca
     5101 tccgaaaact taataatgct ggagaaaatt ttcttactga aagtggagtg tataaattaa
     5161 tctttaaatc aagaaaagaa gaagctgaga gattccaaga ctggataagt gatgaagttt
     5221 taccaagcat aagacaaact ggtgcataca taactaataa tgcaatcccg aaaagttgag
     5281 agaaaaagca agtgagattg aaaaattaca gttgcttata acagtacatc tatgttaaaa
     5341 gaattgttag atgatgcagg ctttgacaat aaatcaaaac tattaacagc taaaacatta
     5401 tataagaaag caggaattga tttaccaata gagataaacg aagaagaaca ttattttgat
     5461 acaaaacaaa tagcatctaa actgaaaata tattctaaga gtaataaacc agctcagatg
     5521 gctgtttgtg agattattaa aaagattgat ttagaagatg gtgaagttaa aggtgtttgg
     5581 taaactaatg gttcttggac tggtactgta aataaatata caaagagtgt aatagataag
     5641 gtgagaactt ggatagagga aaataataga cctaccaaga ttgcaggtga gaagaagaat
     5701 tatcatgtat cttacaaaat tgagtaaatt tatcagttgt attaaataat ttagtttagt
     5761 tttgggggga ttaatacaat gtgtgagaat ttacttgata atatgtatat tgaaaagaga
     5821 aaagaagaat atagaattaa acttttgaaa ataagagaaa cagatataga tatatataat
     5881 aagttagaaa gtatagtata taaactttct gagaaaaaat tagagaaaaa taataaatag
     5941 acatataaag cacttggata ttctactgtt tcaagtgctt tgtttggtat aaaatggtat
     6001 aatggagata gagaattata ttaacccaaa aatggagaaa atagagaaga tgatttagtt
     6061 gacgctttat cagtaggagt acttgcaggt aagacagaat ctctagtact attagttgga
     6121 aatggaataa gtgatactca aaaaagttta ataaataaaa gagaatttag aaatataact
     6181 caaattggtg gaaatggaaa tgagaaagca tttagtgaag tagaaaactt agttaaatag
     6241 attagaaggt agcaactaga gttggttgtt accttctttt tttatacttt ctctctctaa
     6301 gtattttctt tttcatatct tctaatacat ctaatgcagt agtataaaat tgtatattat
     6361 ttctataagg tatagctatt ggaagaatgc ccttgttaac taaaaaaata agaagtacaa
     6421 taaataaaag tgtcataatc attctaataa aataattagt gatatctgat aaatcaaatg
     6481 ttaagttaat tgttgtagaa aatacaacag ccataataga tatatacaaa gcaaaaatgg
     6541 ggttactatt tttttgtaac tgtcctttaa gcctagattg ctctatttct atatcttgaa
     6601 tactttttat ggaatccatt tcactataat acttataaac ttttaaataa tattttttat
     6661 acttgtttaa agcttcttca ttatctttaa ggtctttgtc acttaactct gatttaactt
     6721 ccccaaaatc cataaaatct ctcctacaat gttatatagt atactttaat ttatagcata
     6781 tttaagaact tatatcagca atttgtcgaa caattttagc taaaaataga gtataatgat
     6841 aggcttatta tttataagat attatttttt atatagttat atatttcttt ctaattagat
     6901 aatataatgc tgttgttata atggctacta atattattgc tagtattgta atatctaatc
     6961 ttcttgtaaa taagcctatt gctatatact caagacctgt tacataacga taaagtactt
     7021 ctagtttaac agtttttttc ttatctatat ttccatatat tgattctaat ttattaaaat
     7081 attttttact acaaaaagca gttttaggtt taattaaata tattattgta gttcctatta
     7141 taactattat tccaataagt ataagattga tatttccaaa atccatagca gatacctcct
     7201 attaaatttg cttttcttag tcaaagtata tcagtaacac aagtacaaag agtatataaa
     7261 atattacaaa tattaacagg atagataaaa ctatagtaaa aattgtaata ataaagcgaa
     7321 cgaaaattat catactaaaa cataagacat gttataattg tattagatag aagattaaca
     7381 tacaccaaag cactccttat aataaagagt gcttattttt ttgaaattca tcaatatata
     7441 aactatcaag aatcttattc aacacacctt aaaatcgatt taaatagctc tttttgatag
     7501 cataatttat atgatataat aaaaaaatag aagtgtattc gcagtacact tctatagtta
     7561 taactaagca ttctcatgag cgggagtgtt tttttcattt ctccaaacaa cattattttt
     7621 ttcatcaata attatcaaat caatttcaat atcttctaaa atttctgttg cagtacaaat
     7681 tagattatct aagtcaaaac ttcgagttat ctctagttgt ttgttattta cttctctttt
     7741 tagtatataa gttttaaaat acatttatat caccccttgt atttactctt ttttctctaa
     7801 aaatatattg ataagtaaat atgcaacaaa taaaaaaatc tcaatgacac atagtgttat
     7861 agctataact agaagtgatt gatttttcca tgcactataa gctatgatga aaagaaatgt
     7921 aaaagtaaat aatgtataat tcataatttt aactaagata tgacttgttt tcattgttaa
     7981 gtacaagtct ctttcatctg cactatcgtg taattcttca acaatgcctt ttcttgaaaa
     8041 agcattacaa aaattaaaga ttgctattac aattaaaaga aatgatgaaa ttaggaatct
     8101 tttatctttt aaaatgcaat aaataactaa actagcacaa cataacatac aaactataat
     8161 acccactata aaacttcgtt tactctttac tttcatgttt tttatcctcc atttctttat
     8221 tttcttttaa acaacatagt tcttcaatcg ttgtaccaaa cacttgtgcc atacgatagg
     8281 caagcataag agaagggcta tattgctctt tttcaataga aataattgtt ctgtttgata
     8341 catggactaa atcagcgagt tgttgctgtg ttagacccat atttgttcga aattctcgta
     8401 cttttgtttt cattccataa cctctttcta tatgaagcta acttcatgtg aagttaactt
     8461 cataatatcc taaaatgagt aaaatgtcaa tctcattaga taagtattat aaaacctaaa
     8521 agaataatat ggtaaaaatt ggatggaatt atttacctta attctcttgt ttgtaaaact
     8581 ttattgatat agaatttaac atatacataa atcggcaaag gggtgcgaat tatgaaaatt
     8641 agtaaattac cagaagcgga attaaaagtt atgagatata tttgtgaagc taacaaggta
     8701 ttaacttcta gggaattagt tgctgcaatg gaagaaaaat atgagtggaa tgaatcaact
     8761 acatttacag ttttgaaaag attagagcga agggagtttt taagtacaga gaaaataggc
     8821 aaacttacac attataatat actagtaaaa gagaaaaaat atctaaggtt tgaaacaaag
     8881 gaatttttga agaacataca taaaaattca atttcaagtt taatgtcagc gttacatggt
     8941 gaagacgacg aagtggatga agataaatta agtgaactcg aagaatattt taagaatttg
     9001 aaataagaaa atgacaaatt gatacataat aaataaaatg aaggtatgaa attataactt
     9061 tttctacctt cattttgttt attattctga acatgttaag aaaatgaaat aagtttgtat
     9121 tttagttata taaattttaa tagaatatgt acagtatata gtagatagaa tgtataaaaa
     9181 tagaatttaa ataagtagct attattgcag tgaaatgaat gtttctaagt atatttgggt
     9241 ggaagaatgg tggaagaaag ttagtgaaat gtaattcttc caccattctt ccacccaaaa
     9301 aataaaaact gttcaataag aattaatata catcaattca gctgaatgca atcaaaatac
     9361 ttaaatgaaa gtaatctgaa aacaacataa ttcaaatcaa tttattcaaa taaacctcaa
     9421 tttatcttaa atcttaagaa atatttaaga attaggataa tattttctta agatttatat
     9481 tttattatat agttataagg gaaagttaca aaaatgtaag ccaaagtaat ataacaattt
     9541 agtcattgtt gagaaaggga gtgaaagata ttgtataata tagataagta ttattataca
     9601 atagaggaag tgaaaatatg tacaatatat tagtagtaga cgatgataaa gaaattgttg
     9661 attcgataga aatatatctt aaatcagaag gatttaaaat atataaagca tatgatggaa
     9721 tgaaagcttt ggaaataata acagagaatg acattcatct aatactaatg gatataatga
     9781 tgcctaaatt agatggaatc aaagcaactg taaaaatacg agaagaaaga aatattccaa
     9841 taattttaat ttcagcaaaa agtgaagata cagataaaat aataggatta aatattggag
     9901 ctgatgatta tataacaaag ccatttaatc tattagagct tatagctagg gttaaatcaa
     9961 acttaagacg atatgtaact ttaggtaatt atgaagatac atgtaaagaa attttaaaaa
    10021 gtggagcttt ggagttaaat acactaacaa aagaagttaa aattgatggt gaaaacataa
    10081 aaatgactcc aattgagtat aaaataattg aacttctttt agaaaataaa ggacgagttt
    10141 tctcaataga tgagatatac gaaaaagtat ggaatgagga aagttttaat tcagaaaata
    10201 cagtagcagt acatatcaga cgaataagag aaaagattga aataaatcca aaagaaccaa
    10261 gatttttaaa ggtggtgtgg ggagttggtt ataagattga aaaattttag tggaaaaatt
    10321 ataaaagaaa agagtttaat atttaattgc attttgattt tagtcatttt tacatttaca
    10381 caaatgttag gaattttaat atgttttaat tttttctctg agagtttaat ttactctatg
    10441 gggattatgc ttttcttaaa ctttatttta tataaaatac tgacaatgta gatgaggtgg
    10501 gcaacttgga gaaatataga gtattaaagt tagtttcatt aatcataata tctatctcat
    10561 ttccattaac tatattgttg gtgacaatag gacttgctga gcctaaatac aatatacaaa
    10621 aaacttctac aaagagtggg atttttgata tatctgatga tttttatgat agtaatatat
    10681 ttgacgaagg aacaatggca agtctattac ccaagtttaa gctatctgta ggtggtaaat
    10741 taactagtaa agaaaaaggt aaattccaac aagaaggtaa aagtatagat ttaagtagta
    10801 gtgattctga gtatgataaa atcatgatta atgaacaagc ttctgaagaa tatttaagtt
    10861 atctaaaaaa tataaaagtg tatgttatta atacatacac aggagtattt tatacaaata
    10921 cgtcatatgc tagtttatat gattttaaac aaaaaactaa gagctattgt aatgtagaga
    10981 taataaataa gataggaaag agctcatata ttaaaacaat aaatggagaa aaatttgaac
    11041 tgaataatct gagtctggaa ctaaatgaag tagatgaagg ttttgaggca tatgtatctt
    11101 ttccagaaga gccaactata gaagatggaa tagtatatac taattttcaa atatttaaac
    11161 aagctacaga aaaagtaaga ttattttttg tagctagttt aagtttagca attatatgtt
    11221 tattatctat aattttatat atcaaaataa aaggtgaagt tttaaaaaga aataatgtat
    11281 ttttactaat atacagtaag atacctatgg aatttaatgt aatattagta tctatttcaa
    11341 ttgcaatttt aactatatat gctcttgctg tatcttatca tattgatgta attgcattag
    11401 tttctttatc tttactgata gtatcaaata atatattttt tataaatgtg caattgagtt
    11461 atttagaaaa taaaatgtgt atatttaaga caagtattat agtaagagtg attttatggt
    11521 taataaaaac tgtaagggag gtcagtaacg ctataaagaa agtatcttta gcaaggaaag
    11581 ttattgttat agtgataata tctttagctt taatcatggt aattagcact cgaagtatag
    11641 gtatgggatt actgttttct atatgtattt ttttaggatt tacaatatat ataactaaaa
    11701 gactttcata tcttagttac gtaatagaag gtacagaaag aataaaaaag ggagaattag
    11761 attataagat aaaaattact gggaatgata attttacgtc tttagctgaa aatataaata
    11821 atattggaga aggtcttgat agagctatag aagagcaagt aaaaagtgaa agaatgaagt
    11881 ctgaccttat aacaaatgta tctcatgatt tgaaaactcc acttacttct ataataaatt
    11941 atgtagattt aattaaaaaa gaagaatcaa tacaaccaga gtatataaat gattatataa
    12001 atgtacttga gtcaaagtca aaaagactaa aattattgat agaagattta tttgaagcga
    12061 gtagagtaag tagtggcaat atagaattac aaattagcaa gattgattta gtgcaactat
    12121 taagacaaag tataggtgaa cttgaagaaa aattatctaa aaataattta tatttaaaat
    12181 taaatgttcc aaatgataag gtgtatatat gggcagatgg aagaagaatg tatagagtat
    12241 ttgaaaatct tttatctaat atagcaaaat attccttaga agaaactaga gtctatattg
    12301 atgtatatga ctatggtgaa aatgtaaagg taactatgaa aaatatatct tcttatgaat
    12361 taaattttga cccaagtgag attatggaaa gatttaaaag agctgatgaa tcaaggaata
    12421 ctgaaggaag tggattaggg cttgctattg caagagattt agtagcttta caaggtggaa
    12481 aattttatat agaaatagat ggagatttat ttaaagcaaa tttagagttt caaaaatatg
    12541 aagaagaaat aacaaatatg gaatgagata gtatttaagt atatatattt tttttactgt
    12601 cgaaagcttt tattataata tattagaata tttacagtag agaatgaaga gtaaaaacag
    12661 agtaacttta agtcactctg ttttttattt aaaatcaata atataacaac ttaaattaaa
    12721 attgtacaca tagttttaaa ataacttata caataaaaca ttatccaaat atcacaagat
    12781 aattccaaat aaatatatag atatcactcc tgtaataata gaaataccaa tagatttaaa
    12841 cttatatgca acaagaagta caatcataaa agatataatt ttagggttag ctatagataa
    12901 atatagacta tctccattaa aaaatacatc tttagcagtt aaggaagtaa gtattgctac
    12961 aggtataaat ttcatgattt ttttcaaaaa atcaggcatc tctttttttg aaaaaattaa
    13021 cataggaagc actcttggta gatatgtaac aatgtacatt ccaattataa taaaaaatat
    13081 ataattatta ttcataagat tcctcctttt tacagtaaga ttcttctata aagaaaccaa
    13141 ttaaagatgc taaaattgat gcaactatta ttactaaatt gcttttgaat aatgcatata
    13201 aaataacaga aataatgatt gatgatataa atactacaat ataaatctta ttttttattt
    13261 gagaaactat taaagctata aacatagaag tcaatatgaa gccagaaata gaactgtcta
    13321 tagatatact ttctcctaaa aatgctccaa taaaattagc taaaactgat gaaattaagc
    13381 agaagaaatt aagataaata gcatttctat cagaccaatt tccagcagta aatttttcat
    13441 aattaactgc aaaagtttca tctgttatag tatgacaaaa tggcaatata aattttggac
    13501 ttttattttt tatgtacatg ttcaaattag aactcattag aaaatgtctt aagttaacta
    13561 taaatgtagt caaaacaata gatgttacac ttgcaccagt agaaatcatt gaagctgcaa
    13621 tgaattgaga acttcctcca aatactaaag ttaccattag tgctatttga aaaggtgaaa
    13681 gaccagattt ttgtaatagt attcctccta ctatacctat aggtatataa cctaagaata
    13741 taggaattga agcaataaag ctttctttta attgttgagt tctttccaca ataaatcact
    13801 ccttttgtat taaatgtatt aaagtattcg taaaacagaa aaatagatta attgtataat
    13861 tgcaattata attaaaaata aatttggatt aatatataaa atactataca acaaatagat
    13921 aatcttaaac ggttattaaa ttttatctat ttgttattat gatgtaataa tacatattaa
    13981 tctctataag ttaattacta tctggtgtaa ttttatttta acaacaaaaa aaaatacaca
    14041 caattaaaat attgtgtgca atacaattat tttttctctt ctaatagtct ttttaatacg
    14101 ctcaaaccag ctttaagttc ttctgtactt tctgtagcac atacagctat tcttattgca
    14161 gaaattggtt tttcttttcc aacagcaaaa cgttcagaag catagacctg tacaccttct
    14221 ttaagtgctt gtatctcaaa tttttctgcc attattccat caggtagaat caaccatcta
    14281 aatatacatt cttcatttcc caaaagatta tatccagata aatattgatt aataatcttg
    14341 tttcttcttc ttgcagattt acggcgtgca ttaattaatt tatcggcttc acctgatgta
    14401 atcatgcgat aagcaatttc tgttaaaaaa taagattgag atagattaat gttgtataat
    14461 gcgcttgata atgcctctcg atactgttta ggtgtagaga tatatgctag ccgtaaacta
    14521 ggtgcaataa tttttgataa actcgtaata taaattgttt gattgggcag ataggaagcc
    14581 actggattta aatgtgtttc attaagtaaa ctatgaatag catcctcaat aacaattaaa
    14641 ttgtatttag atgcaatatt tgcaatcatt tttcgtccat tttgtgacat tatatgtgta
    14701 gttggatttt gataatctgg tattatgtat agacctttaa tattttcatt tttacaagca
    14761 tataatagtc cttcttcact aatctcatta tcttcttgtt taattggaat tagttgaatc
    14821 ccaagcattt tagctgctgt ctttattcca ggataagtta atgggtctac acctattcta
    14881 tctccatgtt gaaacaaacc agctaaaata gcaacaattg cattttgtcc accacttgca
    14941 ggaagtaagc tatctgatgt agtttcaagc ccagctttat aaattaattt ggcaatagct
    15001 tctttttgcc atttagcacc atctctttgt ccatattgga atatggtttt aaaacctatt
    15061 tccttaatta tgtgtttaaa caaagtattc atttcttcta gcgtgaaatc tggattcatt
    15121 gtgcccattt caataaatgt aattttatta ttactggaca tcaagaatag atttgaacgt
    15181 gtatcataag atacaaaagt tccacttcct gtaactccac ttattagacc ttttttttca
    15241 caaattttaa aagctctaga gatagtactc acattaacat ctaagaaatc tgccaattca
    15301 cgttggggtg gtaatttagt acctggtaat aaaaatccat tgttgatatc ttgttctagt
    15361 tgttctgcaa gcgccttata taatatttgc ccttttgaag gtctctttgg tttccagttc
    15421 ataggataat tttcaaaaga attaattggc ataagttttc acctcacatt attaatttga
    15481 ttttttcttt atctaaaaca ataaattcta aagatacaaa taaaaactga taggaaataa
    15541 ttctatcagt ttttgtcttt taattgattt caaatcttcc tataattttt ataccttctt
    15601 tatcataaag agggattgtt tttttaaata tattaaaatt tctttttctt gtatataaaa
    15661 cagcttcttc tggtgtcttt ggttgattat cacaatcgta caaatctctt ttttttacgt
    15721 agccgacttt tttacctcta cctattgttt gtataagttc tggttcaatg gaatttccat
    15781 ttgagtctat tatatgtgta ccataggttt ctccattttt attataatta atcttaccaa
    15841 tagtatattc tacatcttca ttttgtttaa aattggagtt gatagaaaat attgacccta
    15901 ttattataaa ggttaataaa aacttaagac ctaaattaat tttcttttta tcttgattaa
    15961 acatagaatt taacctcttt tttaaaataa tatttttttt atttagaaac tgagatacga
    16021 atgatgaata cttcaaagat ttttgatact ttattgtatc taatattata tatgcatact
    16081 ctttaatttc actcgtggta cacttgtcaa tcacaatttc atcacaagat aattcacata
    16141 attcatgaaa atattttttt aataagtata aaattggatt gaaccaatat atgatacaaa
    16201 ttatactaat tagaagctta aataagttat cttttctttt ataatgaatt aattcatgtt
    16261 taaagatgaa tcttaactct ttattattgt actttttttc tggaattatt attttacagc
    16321 gtgttaaacc tataatggca ggagaataaa tacctttaac cttatatatc tgaagttttt
    16381 tatttatact tagttctttt gcttgttcat ctaagatact agtaatatct atttctaaaa
    16441 tttctttttt aaaattttct atgtaattat aaaatttaaa atttgttctt aaatagtaaa
    16501 aagagattgc tataattcct aatatccaga tgtacataaa tatatctaaa gtaatgccct
    16561 ggtcatatgg tatataatta tcgatattat gcttata
//
LOCUS       DAMKNB010000079        16587 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.083, whole genome shotgun sequence.
ACCESSION   DAMKNB010000079 DAMKNB010000000
VERSION     DAMKNB010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 16587)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16587)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16587
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.083"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            complement(86..358)
                     /locus_tag="PC494_002869"
     CDS             complement(86..358)
                     /locus_tag="PC494_002869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3913355.1"
                     /translation="MYDEIIEIYFDYWINEHMYRDILEKDKYYIESWKEVKKINELLE
                     KVLEDDKKYVLVELNDLFNSLIEFERELSYKLGFKTGAKFIIELMD"
     gene            complement(606..1940)
                     /locus_tag="PC494_002870"
     CDS             complement(606..1940)
                     /locus_tag="PC494_002870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HDF3913356.1"
                     /translation="MNNSNNLIKNTEAEQSILGSILLDSTIVQELEQMLNEDMFYHEE
                     HKYIFNAIKEINKRNEVIDIITLTEELKRKGHLNNIGGISYITSLSTIVPTVSNFMSY
                     VSIVIEKYKNRNIIDKFKKFNLGEIDDNTLIYQLENDINKANQKLIKKDSSITAISER
                     AFEYINDEVNEGIKTGIKFLDDTIGGLYGGELTTIAAKSGRGKTALALQILRNVIFQG
                     KKVLFISGEMSDIQILFRNIASLTGISVVKMKNRNLNDEEIVKYIQALSIINQENNLY
                     INDSVNTISGIKREIKSIKPSLVIIDYLQILDYEGKEVGEAKFADLSRQIKKITLDFN
                     IPVIQLAQLNDELKDERPKGDRVMRSSKQIYMDSNSVIYIHRPTEKEALNYCKTMGIE
                     DIRELRRREKGFGANLSEIIVAKNRDGESGFRPYWYIGNLFSFEECKKIQEI"
     gene            complement(1953..2696)
                     /locus_tag="PC494_002871"
     CDS             complement(1953..2696)
                     /locus_tag="PC494_002871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3913357.1"
                     /translation="MSNKGWIKLYRELLDKSIWKDIKPERKVILITLLLMASHKENHV
                     FIDNKRIKIKSGQFISSYSKIAERCGKGVSYQMVRSCLLVFKNAGFLTYETTNKYIVI
                     TIENWELYQENIENQQPNQQTINNQSTTIKNIKNENNIIYSEIISKFNSTCIELSKVK
                     KLTDTRKRRINSRIKEYDKETVLEVINIVSKTSFLNGNNNTGWKANFDWIMNSSNFTK
                     ILEGNYNSKEIVINKETGIYNPDDSQLKW"
     gene            complement(2718..3032)
                     /locus_tag="PC494_002872"
     CDS             complement(2718..3032)
                     /locus_tag="PC494_002872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3913358.1"
                     /translation="MKENNNLEVLKTLQATLNIIVKNEEEAQEKKQGYKIIENAKRNK
                     AELITCKEASKLYPIGESKFRQLCHSKNKGFPCIWINNRVYIIKNKLDDWFIENANGI
                     KL"
     gene            complement(3036..3236)
                     /locus_tag="PC494_002873"
     CDS             complement(3036..3236)
                     /locus_tag="PC494_002873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF3913359.1"
                     /translation="MGINLKIFRIKKGLKQQELADRVGISRYYLSNLETGKANNPSND
                     LMIKLSRALDTTVEELFFSKED"
     gene            3383..4147
                     /locus_tag="PC494_002874"
     CDS             3383..4147
                     /locus_tag="PC494_002874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF3913360.1"
                     /translation="MQIGKNLKNIRKQKELTQIQLAEISGISRNALINYENDKRIPSI
                     DTLSKLAKALKIEKTIFYFDIENEVMTNEDVLYLLQSLFPEEYYSFDEFLNAISNLME
                     DDDIRITSSLLLGAWSDKDQYYKLGEKLELNENQVYNWILSDCISNTELDFSLHPDDI
                     KEIIKNDVLTKQSIDELLDIGLSEENIETIYDYFSDSTDNGSNIRLKKLISQKENITI
                     KNNDYFKLLQENNELKEKNEKLENTLKEIKKLLTKI"
     gene            4204..4402
                     /locus_tag="PC494_002875"
                     /pseudo
     CDS             4204..4402
                     /locus_tag="PC494_002875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729178.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            4399..4890
                     /locus_tag="PC494_002876"
     CDS             4399..4890
                     /locus_tag="PC494_002876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF3913361.1"
                     /translation="MMNNTIGEKIKQYRKSINMSRDELANKIGCSVHAIAKYEQNQRM
                     PSLDMIRKIATALSIAINKLIVEENDLDTLTNNNINLKVFDKELDLVIHILENYGYDI
                     KTDYKKKFEITDNADTIKPINLNFSDFKDFSKNLNWVINGLVENFIQENSNGLIEDED
                     EEY"
     gene            4982..5734
                     /locus_tag="PC494_002877"
     CDS             4982..5734
                     /locus_tag="PC494_002877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic family protein"
                     /protein_id="HDF3913362.1"
                     /translation="MNKSYIPKYTHKFPTNLPHGDKKYTLTYIRRMISEFVYDMGNLE
                     NNPFTFPEVQTLLDGITVGGHKLSDQNQILNIKSSWDYVIKLSNKENLSLNKDTICSI
                     HKIVAKDEALIVGDFRNGNIGIAGTTQYECIEATLLNDLFVNDINIINKITNPLEKAI
                     IINLWLSYCQFFYDGNKRTARLTSNLILISNDIGVLSIPAKHKQEYNTLMLNFYETLE
                     ADEVIKFLLEKCITFFDGYNYKSYKELFKNGN"
     gene            5724..6890
                     /locus_tag="PC494_002878"
     CDS             5724..6890
                     /locus_tag="PC494_002878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HDF3913363.1"
                     /translation="MATKRANGEGSIGKYKDGWRSRIMIGYNEDGKPIRKEFYGKTQK
                     EVKDKLDAYKKQYYLSSDISDDKITLEHWFYNWLFEYRIKDLKPKSFERYESIYRNYI
                     KDTDLGNVKLKDLRVSHIQKYYNRLLDSNKSIPTIRQINTKLKTCLSEAEKQGLIQRN
                     YCTMVNIPVEKKENKLEILTLEQQKSFIKAIDGHKLEVLFLLALGTGLRLGELLGLKW
                     FDIDFKKSNLTVKRTLQRTYFIDKTGNRELKVLEQEPKTSNSYRTVPIPKDVLNKLKE
                     HKVNQNSDILKAGELYRNDNYVFCNELGIPIDDKRPLRNLKSILNSLDIEPIKFHGLR
                     KTYATRLFENDVPPKTVQVLMGHYDISITLNIYTQVMEDKKVEAVEKLDKIFSL"
     gene            complement(7006..7236)
                     /locus_tag="PC494_002879"
     CDS             complement(7006..7236)
                     /locus_tag="PC494_002879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3913364.1"
                     /translation="MEANKTLLQILYKKIILEFSKQTGKSLEESMDYLYTSETYKLIS
                     EGVADMHCKGHIYLAQELMLENGLMYHKGYPR"
     gene            complement(7242..7721)
                     /locus_tag="PC494_002880"
     CDS             complement(7242..7721)
                     /locus_tag="PC494_002880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003361465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3990 domain-containing protein"
                     /protein_id="HDF3913365.1"
                     /translation="MIVYHGSYCVVKTPSITFSRDSLDFGKGFYVTSIKTQAINWTER
                     FKKRGKKAYLNSYSLDIDKLKENCKVKIFNSYNLEWLDFIIECRNMSDIYMKYDIIIG
                     GIADDKIYNTIELYQDNLIEKDEALKRLKYYKPNEQICITNQNVIDKYLKFRYEEEV"
     gene            complement(7721..7936)
                     /locus_tag="PC494_002881"
     CDS             complement(7721..7936)
                     /locus_tag="PC494_002881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3791 domain-containing protein"
                     /protein_id="HDF3913366.1"
                     /translation="MDERKLEFSIFCIEALAEKLNIDSEGVYKLLKHDTDILDNYIIP
                     CYEALHSQSKGYIVEDLMQVLKEKGVI"
     gene            complement(8252..8601)
                     /gene="ssrA"
                     /locus_tag="PC494_002882"
     tmRNA           complement(8252..8601)
                     /gene="ssrA"
                     /locus_tag="PC494_002882"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            complement(8759..9214)
                     /gene="smpB"
                     /locus_tag="PC494_002883"
     CDS             complement(8759..9214)
                     /gene="smpB"
                     /locus_tag="PC494_002883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HDF3913367.1"
                     /translation="MAGKKILATNKRARHEYFIEETYECGIELKGTEVKSIRQGKVNL
                     SDGFASVDNSEVFLKQVHISPYEQGNIFNVDSLRVRKLLLHKHEIRKLIGATTIKGYS
                     LIPLSLYLKNGKVKVEIALAKGKKLYDKRQDMAKKDAQRRIEREMTGKY"
     gene            9834..10661
                     /locus_tag="PC494_002884"
     CDS             9834..10661
                     /locus_tag="PC494_002884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AIM24 family protein"
                     /protein_id="HDF3913368.1"
                     /translation="MDLSKKVKILENASDGKSEFEILEFEKLEGASSPLMAMGLYFAR
                     EAGLKARQIKIKLNNSSIKTEAGALYYYKGNISSETKIGGVGGLFKKGISGALTNESM
                     MKPVYKGTGEVYLEPSFRHYLFMSLDNDSIIVDKGLFYCCSDTIEVKAFTQKNFSSAL
                     LGGEGFFQIELSGTGVIVLECVVPQSEIVEYELKNGEELKVDGNFAIARTSGVNFSVT
                     KSDKSLIGSALNGEGFLNTFTGNGTVWLAPTQVMYEKLSFGAMPTNDNMNNKVSKQK"
     gene            11686..12150
                     /locus_tag="PC494_002885"
     CDS             11686..12150
                     /locus_tag="PC494_002885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDF3913369.1"
                     /translation="MNLNKVKFTEEHAIEVTNWKYEGKYSIYNLPPWEEIKKKNFSLA
                     KEDKRKNFISFINDNKELIGFINLLDEGSSVFFGIGMKPNYCGMGIGKEIIGLGLQEC
                     RNKYSTKPIVLNVRTWNMRAVKCYESQGFKIVETKVQKTHLGDGEFFVMRYQ"
     gene            complement(12417..13061)
                     /locus_tag="PC494_002886"
     CDS             complement(12417..13061)
                     /locus_tag="PC494_002886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF3913370.1"
                     /translation="MFGQSFQNYLVLIKENFKLSTLTNLICSIILLCMIPLIQGVANL
                     DRISTAICLENYVAIIGIVMLVPVFSLEQSKEIDEIVSSKALSQVIVQLIRILMSIIG
                     IVVLIIGFVNVLIYLGCNFPVVEYIIGSFASAMFIGSLGMFFSNLFNNTIIGYMISIG
                     YLILNMMTKGKYVGKFFIMSMSQGSFDEKYWLILGSVVLIIASLLIKPVKRKIR"
     gene            complement(12991..14280)
                     /locus_tag="PC494_002887"
     CDS             complement(12991..14280)
                     /locus_tag="PC494_002887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF3913371.1"
                     /translation="MNLFIKECKNILKSMIYYIFIVVLVFFYISQLGSSVSNDVSKNI
                     PNDGNPLVAPQKVENIEEYYSVHNQYPYGQKESMKTEKVIPNATINLIREYQKNTYTT
                     YPTGVVKYIKLDQNKTKTIEKYIEEITGKSISEINSLWKTDESIKIDYSKVSLERFEE
                     IMQRVDDILGGGSAYAFDKLQRFGVVPVTYDEAMKNYNYTIQKDKVSNGYARIFCDYI
                     GIVLSIFPVFVAVFMSLKDKRSRMREIIYSKQVSSCKIVLSRYFALVFMMILPVLILG
                     MKDLLPLIFFAKDKGISIDNLAFIKYTLWWILPTLMIVTAVGMSITILTDTPVAIIVQ
                     LIWWFYSINSTGLKGDYSTMGLMIRHNSVLNGDIIIQNFNQIMINRIVISLEALVLVL
                     LAIFLYEQKRRGNLDVWAKFSKLFSSNKRKLQIKHFN"
     gene            complement(14277..15149)
                     /locus_tag="PC494_002888"
     CDS             complement(14277..15149)
                     /locus_tag="PC494_002888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF3913372.1"
                     /translation="MEMKIAVSNLSKRFGKKQALDNINLEIDSGMFGLLGRNGAGKTT
                     FMRILATLLSKTEGSIHMCGVPIENTKEIRNMVGYLPQDFSMYPNMTVYKAMDYLAVL
                     SDIPLRKRRKIIAKLLSKVNLTNYQNVKVKSLSGGMNRRLGIAQALIHNPRVLIVDEP
                     TAGLDPEERIRFRNLLCEIANDRIVILSTHIVGDIEATCENVAILNSGKVIYNGSTEA
                     LAKLAEGKVYSIEVDKKDIENIKSRFIVIGMLTHGGKAILRIISDDKPFETAVNCNPT
                     IEDGYMLIMGGDNI"
     gene            complement(15678..16169)
                     /locus_tag="PC494_002889"
     CDS             complement(15678..16169)
                     /locus_tag="PC494_002889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfbM family protein"
                     /protein_id="HDF3913373.1"
                     /translation="MGMIGCYTKISEENVFKLQQAEENLQDFVFEDANENSTINIDKA
                     WHAIHFTLTGCPFGGDDDNIFSKLVLSGNILMEIDGEFPVMLITANDVKKLSKAMNSL
                     EEQAFRKRFNINEMLENNIYPVMNDESEDDFFEYVWANLIELKKFIQEASNDGLAVIF
                     FIM"
BASE COUNT         5955 a         2424 c         1895 g         6313 t
ORIGIN      
        1 actaatataa tgctaaatta aaaaggacac ttttaatgtc ctctttaatt tagcattata
       61 gaattaactt ataagcataa gtaaattaat ccattaattc tattataaat tttgctcctg
      121 ttttaaatcc taatttataa ctaagttccc tttcaaactc tattaatgaa ttaaacaaat
      181 catttaattc aaccaacaca tatttcttat catcctccaa aactttttct aataactcat
      241 taattttttt aacctctttc caactttcaa tataatattt gtctttttct aaaatatctc
      301 tatacatatg ttcatttatc caataatcaa aatatatttc tataatttca tcatacattt
      361 tagtacctcc ttgactttcc tcaggcactt aatatatact taagttgcta ggttagtgta
      421 catcaagtac ctaatttata aaggtagttg ttatatttat atggcaacta cctttttcta
      481 ataagtgttt aaatctaaac taaatatatt ttaaatcttt attacatcta attaaaattt
      541 atatttatac ttcaacactt cttgaaacat aatttatcta ttacttaata aatcatgctt
      601 cttttttata tctcttgtat cttcttacat tcttcaaaag aaaacaaatt tcctatatac
      661 caatatggtc taaatcctga ctcgccatct ctatttttag caacaataat ctcacttaaa
      721 ttagcaccaa aacctttttc tcttcgtctc aactctctta tatcctcaat tcccattgtc
      781 ttacaataat taagagcttc tttttctgta ggtctatgaa tatatataac tgaattagaa
      841 tccatatata tctgctttga gcttctcatc actctatcac ctttaggtct ttcatctttc
      901 aattcatcat ttaattgagc aagctgaata actggtatat taaaatctaa agtaatcttt
      961 tttatttgcc ttgataagtc agcaaattta gcttctccta cttctttacc ttcataatcc
     1021 aaaatttgca aataatcaat tatgactaag ctaggcttaa tactctttat ttctctcttt
     1081 attcctgata ttgtatttac agagtcattt atataaagat tattttcctg atttattatg
     1141 cttaaagctt gtatatattt gactatttct tcatcattta gatttctatt tttcatcttt
     1201 acaactgata ttccagttag tgatgctata tttctaaata gaatctgtat atcgctcatt
     1261 tctccactta taaaaagtac tttcttacct tgaaatatta catttctaag tatttgtaac
     1321 gccaatgctg ttttacctct tccactttta gctgctattg tagttagttc acccccatat
     1381 aaacctccta tagtatcatc taagaacttt attccagttt taataccttc atttacttca
     1441 tcatttatat attcaaaggc tctctctgat atggctgtta tacttgaatc cttttttatt
     1501 aatttctgat tagctttatt tatatcattt tctaactgat atataagagt attatcatct
     1561 atttctccaa gattgaactt tttgaattta tcaattatat ttctattttt gtatttttca
     1621 ataactatac ttacataact catgaaattt gatactgttg gaactattgt tgacaaacta
     1681 gtgatatagc ttatacctcc aatattattc aaatgacctt ttctctttaa ttcttctgta
     1741 agagttatta tatctattac ttcatttctc ttatttattt cttttatagc attaaatatg
     1801 tatttatgtt cctcatgata aaacatgtct tcatttaaca tttgctctaa ctcttgtact
     1861 attgttgaat ctaataaaat acttcctaat attgattgct ctgcttctgt atttttaatt
     1921 aagttgtttg aattatttat aatataacct ccttaccact ttaattgtga gtcatctgga
     1981 ttatatattc ctgtctcttt atttatgaca atttccttgc tattataatt tccctctagt
     2041 atcttagtaa aattacttga attcattatc caatcaaaat ttgctttcca tcctgtatta
     2101 ttatttccat tcagaaaact tgttttacta actatattta taacctctaa tacagtttct
     2161 ttatcatatt cttttattct tgaatttatt ctcctctttc ttgtatctgt tagtttcttg
     2221 acctttgaaa gttcaataca agttgagtta aatttgctta tgatttcact atatataata
     2281 ttattttcat tctttatatt cttgattgtt gttgattgat tgttaatagt ctgttgatta
     2341 ggttgttgat tttctatgtt ctcttgataa agctcccagt tttcaatagt tatgactata
     2401 tacttgtttg ttgtttcgta tgttagaaaa ccagcatttt taaaaaccaa caaacaactt
     2461 ctaaccattt gataactaac tcctttacca catctttcag ctattttgct ataggaagaa
     2521 ataaattgtc cagattttat ttttatcctt ttattatcta taaaaacatg gttttcttta
     2581 tgactagcca taagtaatag agttattaat attacttttc tttctggttt aatgtctttc
     2641 caaattgatt tatccaacaa ctccctataa agctttatcc accctttatt gctcaattac
     2701 aaacacctac tttaaggcta taacttgata ccatttgcat tttcaataaa ccaatcatct
     2761 aatttatttt ttattatgta tactcgatta tttatccata tacaagggaa tcctttgttt
     2821 ttagaatgac ataactgcct aaattttgat tctcctatag gataaagctt agatgcttct
     2881 ttacatgtta taagttcagc tttatttctt ttcgcatttt caataatttt atatccttgc
     2941 tttttttctt gtgcttcttc ttcattcttt acaataatgt ttaaagtggc ttgtaatgtc
     3001 tttaaaacct ctaaattatt attctctttc atattttaat cctccttact aaaaaataat
     3061 tcttctactg ttgtatctaa agctctagat agtttaatca tcaaatcatt gcttggatta
     3121 ttagccttac ctgtttccaa gtttgataaa taatatcttg atataccaac tctatctgcc
     3181 agttcttgtt gctttagacc ttttttaatc ctaaatattt ttaaattgat tcccatactt
     3241 tttcctcctt ttttctagtt tacattcgta aactttacat tttaattata atgtcgacat
     3301 atgtgtactg taaataaaaa tatattattt ttctgttctc atttgtgtac ttttgggcta
     3361 tactttatac gaggtgataa tattgcaaat tggaaaaaac ttaaaaaata taagaaaaca
     3421 aaaagaacta acgcagattc aacttgctga aattagtggc atctcaagaa atgctctaat
     3481 aaattatgaa aatgataaga gaatacctag tatagatacc ttatcaaaac tcgctaaagc
     3541 tttgaaaatt gaaaagacta tcttttattt tgatattgaa aatgaagtaa tgactaatga
     3601 agatgtttta taccttttac agtctttatt cccagaagaa tactattctt ttgatgaatt
     3661 tttaaatgct atttcaaatc ttatggaaga tgatgatatt agaattacct caagtttatt
     3721 gctaggtgcc tggtctgata aagaccaata ttataaactt ggtgaaaaat tagaactaaa
     3781 tgaaaatcaa gtttataatt ggatactttc agattgtata tctaatactg aattagattt
     3841 ttcattacat cctgatgaca taaaagaaat tattaaaaat gatgttctta caaaacaatc
     3901 aattgatgaa ttattagata ttggtctatc agaagaaaat atagaaacaa tctatgatta
     3961 ctttagtgac tcaacagata atggaagtaa tattcgacta aaaaaattaa tatctcaaaa
     4021 agaaaatatt actattaaaa ataatgatta ctttaaatta ttacaagaaa ataacgaact
     4081 aaaggaaaaa aatgaaaagc ttgaaaatac acttaaagaa ataaaaaaac tactaactaa
     4141 aatataaaat aatatcaata ctatctaaag caatgataaa aaactatgaa tggagttaca
     4201 attatgaata aatcatatat gctaaaatac acatataaat gccctactaa tttatttcat
     4261 ggagataaaa aatatactct aacatacact aagagagtta tgagtaattt agtatatgat
     4321 atgggataat ctagaaaata actcctttac atgtttagaa gtacaatcat tgtttgatga
     4381 tatatttaag gtgaaattat gatgaataat acaattggag aaaagattaa acaatataga
     4441 aaatcgataa atatgtcaag ggatgagcta gccaacaaga ttggttgttc agttcatgct
     4501 atagctaaat atgagcaaaa tcaaagaatg cctagtttag atatgataag aaaaatagct
     4561 actgctttat caattgctat aaataaactc attgttgaag aaaatgattt agatacttta
     4621 acaaataata atattaattt aaaagtattt gataaagagt tggatttagt aattcacata
     4681 ttagaaaatt atggttatga tataaaaaca gactataaaa aaaagtttga aattacagat
     4741 aatgcagata caataaaacc aattaaccta aacttctctg acttcaaaga cttctccaaa
     4801 aatctaaatt gggtgataaa tggtcttgtt gaaaatttta tacaagaaaa ctctaatggt
     4861 cttattgaag atgaggatga agaatattag tattgcacat tttcaaaata tgagtttacc
     4921 tattaacttt tatacattca tagttaataa ataaaaatta gatatgaaag gagctaaaat
     4981 catgaataaa tcatatatac caaaatacac acataaattc cctactaatc tacctcatgg
     5041 agataaaaaa tatactttaa catacattag aagaatgata agtgaatttg tatatgatat
     5101 gggtaaccta gaaaataacc cctttacatt cccagaagta caaacattac ttgatggtat
     5161 aaccgtaggc ggacataaat taagtgacca aaatcaaata ctaaatataa aatcatcatg
     5221 ggattatgta ataaaattaa gtaacaaaga aaacttatct ttaaataaag atacaatttg
     5281 ctctatacat aaaatagttg caaaagatga agctctaatc gttggagatt tcagaaatgg
     5341 taatataggt atagctggta ctactcaata tgaatgcata gaagccactc tattaaatga
     5401 tttatttgta aatgacataa atatcataaa taaaataact aaccccttag aaaaggctat
     5461 aataataaat ttatggttat cctattgcca attcttctat gatggcaaca aaagaactgc
     5521 tagacttacc tcaaacctaa tacttataag taatgatata ggagttctat caataccagc
     5581 taaacataaa caagaataca acacattaat gctaaacttt tatgaaacac tagaagctga
     5641 tgaagttata aaattcttat tagagaaatg tattacattc ttcgatggat ataactataa
     5701 atcatataag gagttgttta aaaatggcaa ctaaaagagc taatggagaa ggctctatcg
     5761 gaaaatataa agatggttgg cgttctcgta taatgattgg ttataatgaa gatggaaaac
     5821 caataagaaa agaattttat ggtaaaactc aaaaggaagt taaagataaa cttgatgctt
     5881 ataaaaaaca atattatcta agttctgata tttcagatga taaaataact ttagaacatt
     5941 ggttttacaa ttggttattt gaatatagaa taaaagattt aaaaccaaag tcatttgaaa
     6001 gatatgaaag catctatcgt aattatatta aagatactga tttaggcaat gttaagttaa
     6061 aggacttaag agtatctcac atacaaaaat attacaatag attgcttgat tccaataaaa
     6121 gtatacctac tataaggcaa ataaacacta aactgaaaac ctgcttatca gaagctgaaa
     6181 aacaaggtct tatacaacgt aattattgta ctatggtaaa tataccagtt gagaaaaagg
     6241 aaaataagct tgaaatattg actcttgaac aacaaaagag ttttataaaa gctatagatg
     6301 gtcataaatt agaggtatta tttttacttg ctcttggtac tggacttaga ttaggagaat
     6361 tattaggact taaatggttt gatattgatt ttaaaaagtc taatttaaca gttaaaagaa
     6421 ctcttcaaag aacatatttt atagataaaa ctggaaatag agagcttaaa gtattagagc
     6481 aagagccaaa gacatcaaat tcttacagaa ctgtacctat tccaaaagat gttttaaata
     6541 aattgaaaga gcataaagta aatcaaaatt cggatatatt aaaggctgga gaattatata
     6601 gaaatgataa ttatgtattt tgcaatgaat taggtatccc tatagatgat aaaagacctt
     6661 taaggaatct aaagtctata ttaaacagtt tagatataga gcctataaag tttcatggtc
     6721 ttagaaaaac ttatgctact agactttttg agaatgatgt tcctcctaaa actgtacaag
     6781 ttttaatggg ccattatgat atatcaataa ctttaaatat atatactcaa gttatggaag
     6841 ataagaaggt tgaagctgta gaaaagttgg ataaaatatt ttcattgtaa aaatcaaata
     6901 catataaata ttgtaatttc atatagttaa ttacaaaatc aaaataagga tacaaattaa
     6961 ttttatatta tcttgtatcc ttatttcgta tctagtttta attatttatc ttggatagcc
     7021 tttatgatac attaatccat tttctaacat taattcttga gccaagtata tatgaccctt
     7081 acagtgcata tctgccacac cttcacttat aagtttatat gtttcagaag tatataaata
     7141 atccatactt tcttccaagc tcttacctgt ttgcttagaa aattctaata tgattttttt
     7201 atatagtatt tgtaataatg ttttatttgc ttccataatc actatacctc ctcttcatac
     7261 ctaaacttta aatatttatc tattacattt tgattggtta tacatatttg ttcatttggt
     7321 ttatagtatt ttaatctttt taaagcttca tctttttcaa taagattatc ctgatacagt
     7381 tctattgtat tgtaaatctt atcatcagca ataccaccta ttataatgtc atatttcata
     7441 tatatatcac tcatatttct acattctatt ataaaatcaa gccattctaa attataacta
     7501 ttgaagattt ttaccttgca gttttctttt aatttatcaa tatctaaaga ataactattt
     7561 aaatatgctt ttttacctct ttttttaaaa cgctctgtcc agttaattgc ttgtgtcttt
     7621 atactggtta catagaatcc ttttccaaaa tctaaagaat ctcttgaaaa ggtaatacta
     7681 ggagtcttta ccacacaata tgaaccatga tatacaatca ttatatcaca cccttttctt
     7741 taagtacttg cattaaatct tccactatgt aacctttact ttgagaatgt agtgcttcat
     7801 agcaaggtat tatatagtta tctaaaatat cagtatcatg tttaagaagt ttataaactc
     7861 cttctgaatc tatattcaat ttttctgcta aagcttcaat gcaaaaaata gaaaattcta
     7921 gttttctttc atccattaca aacctcaact cctatcaagc ttatataata tatattttta
     7981 ctaattaaca acttaaacta tcttacattt ataaaaatat tatatcataa agtagatatt
     8041 aaaattctat gttacctatt atcataataa acaaataaaa taataaacaa ataaaaactt
     8101 tttatacaac ctaaatgcac cccaatatac ccccaaaaaa acctcttttc ctgtggttgg
     8161 ggtacggttg gtggatttta tctccaaaat aaaaaatact agtcaacaaa gactagtatt
     8221 tccaagcatt tcatcattct ttttttaaaa ttggtggaga cgaggggagt cgaacccctg
     8281 tccgcaaatc ttttccttgc tgcatctaca tgcttagcca acttcactaa tatctcacct
     8341 cacatagcgc caagtggcag gctctatgct tagccagtcc caattaatct acttcaagtc
     8401 gagacacccc taaagtagtt ccctgcataa tgacgtccag tcttagtcgg caggaggact
     8461 aagagggacg agcagcaact aggctgctat cgcgaaatta tcgtctgcgt ttattttaaa
     8521 gttccccagt ttttacgtga cccagagtaa cacgacatgc agcctcaagt tccaaaccca
     8581 cgtcgaaacc tttacgcccc cttgagtagt ttatagtcca gtagactttt cgcaaacttt
     8641 atcaccattt ttattaaatt tttaatgtat atataatata atacttttaa gaataaaaat
     8701 caatgttatg ttctagataa taaagaattt tattctaaaa aatacagttt tatctagttt
     8761 aatacttacc tgtcatttct ctttctatac gtctttgtgc atctttctta gccatatctt
     8821 gacgtttatc atatagtttt ttaccttttg ctaaggcaat ctctacttta actttaccgt
     8881 tttttagata caaactaagt ggtataagtg aatacccctt tatagtagtt gctccaataa
     8941 gttttcttat ttcatgctta tgaagtaata attttctaac tcttaaagaa tcaacattga
     9001 atatatttcc ttgctcatat ggacttatat gaacttgttt taaaaatact tcgctattat
     9061 ctacagatgc aaatccatca cttaggttaa ctttgccttg tcttattgat tttacttctg
     9121 ttccttttaa ttcaattcca cattcataag tttcttctat aaaatattca tgtcttgctc
     9181 ttttgtttgt tgctaatatt tttttaccag ccatataaat ctcaccttct ttgctagaaa
     9241 tttcttccat aaatgttaga aatttactaa atatttaatg ttgccaaatt atttgactaa
     9301 cttgtatgat aacatattta ggcattttag tcaatatttc actgatatat taagttagtt
     9361 aggctatata taattaagta atataaatgt atgaaaatag ctaaaaaact acttcgaata
     9421 tacttaatac taaactaact ctaaccagta atactaattt ataaatttca aaacaaaaat
     9481 attacatatt ataaatcttc tatcttctat cttctatctt ctatcttcta tcttctatct
     9541 tctatcttct atcttctatc ttctatcttc tatcttctat cttctatctt ctaaataatt
     9601 ttaacatgcc cataaaatat aatacccaca aatgataaat aatactcaaa atatctattg
     9661 aaataactat acatccttaa ataacttaac ttaaatctaa acatttcaaa aacttcttaa
     9721 aaatatgtaa aaatttgatg ataaagtagc gattttttca aaaaaaatgt aatatagagt
     9781 tatatcttat aatattttag agataaattt tatcatagtg gggagaaatt tgtatggatt
     9841 taagcaaaaa agtaaaaatt ttagaaaatg catcagatgg caaaagcgaa tttgagatat
     9901 tagaatttga aaaacttgag ggagcttcta gcccattaat ggcaatggga ttatattttg
     9961 ctagagaagc tggtttgaaa gctagacaaa ttaagataaa attaaataat tcatcaataa
    10021 aaacagaagc tggtgcatta tactattata aaggaaatat atcttctgaa actaagattg
    10081 gtggtgttgg aggtcttttt aaaaaaggaa tatcaggagc acttactaat gaatcaatga
    10141 tgaaacctgt atacaaaggt actggagaag tttatttgga accttctttt agacattatt
    10201 tatttatgag tcttgataat gattctataa ttgttgataa aggattattc tattgttgct
    10261 ctgatacaat agaagtaaaa gcatttacac aaaagaactt ctcatctgct ttacttggtg
    10321 gtgaaggctt cttccaaata gaattaagtg gtactggtgt aatcgttctg gaatgtgttg
    10381 tacctcaaag tgaaattgta gagtatgaat tgaaaaatgg tgaagaatta aaggtagatg
    10441 gtaactttgc aatagcaaga acatctggtg ttaatttttc tgttacaaaa tcagataaat
    10501 ctttaattgg ttctgcttta aatggtgaag gtttcttaaa tacatttact ggtaatggta
    10561 cagtttggct agctccaact caagtaatgt atgaaaaact aagttttgga gcaatgccta
    10621 ctaatgataa tatgaataat aaagtttcta agcaaaaata gttgttttat aaatatttat
    10681 taaatcatta ttgattttat aaagtcacta taaattttat tagattatta ttataaaatc
    10741 agagtgtgga aatgtttatg tgtattcttt aaataaaaat ttccacattc tgtaaggtta
    10801 ttatacttga tatataaaat tcaatttagg aacatagtct aacatttata aacatattaa
    10861 ggtaatgatt tctcttagta attattctca tatcttattc tttgattata tttatcttat
    10921 tcctagccct tatgtcatat tatatttctt atcttattat ttataattag cattaactta
    10981 tctaaaatct tgtatttttt taatagtaaa gtttacatct atattaaaaa gtttacatct
    11041 atattaattt cataaaacaa tcaaggtagt caagagattc aactttattt gattttaaaa
    11101 atttaagtga atttgttctt atacacacct ttttaaaatt atatctgtag aaaatatcat
    11161 ttagagctat aattaaatta acttattaaa ttttagaaaa tttattaaaa aatataagtt
    11221 aaattaatgt ttttaaagat tcttttttgt aactactaga atactaattt agtagttatt
    11281 gtatctctaa agtttaagca tggatagata tacatttgat aatttgccta taatttacct
    11341 actacttgga ttattggagc aaatacaata tattaataat aagttcctaa aaccaataaa
    11401 ttaactaata cacataaaga tattgatgtt ggttatacaa ctataagaaa cggatttaac
    11461 agaatttaat caagctaaga aattatatat atatcgtgat atttttgaat tagaaggtaa
    11521 ttcaaaatta gtttatagtc ttctgtgaat ccaataaaaa gtacagggta caagaattgt
    11581 tagtaaaatt tttaaagatt ttatggataa atataaatag ttttactcat tgtctaaaac
    11641 tttaaaatac cattaattac cttaaatatt ttaataggag gacatatgaa tttaaataaa
    11701 gttaaattta ctgaagaaca tgctattgaa gttactaatt ggaaatatga aggtaaatat
    11761 tcaatataca atctacctcc atgggaggaa attaaaaaga agaatttttc actagcaaaa
    11821 gaagataaaa gaaaaaattt tataagtttt ataaatgaca ataaagaatt gataggtttt
    11881 ataaacttat tagatgaagg aagctctgta ttctttggta ttggtatgaa accgaattat
    11941 tgtggaatgg gaattggtaa agaaataatt ggcctaggat tacaagaatg tagaaataaa
    12001 tatagtacta aaccaattgt attaaatgta agaacctgga acatgagagc tgtaaaatgt
    12061 tatgagtctc aaggatttaa aatagttgag actaaggtac agaaaacgca tttaggagat
    12121 ggagaatttt ttgttatgag gtatcaatag tttataacaa tagtcttatt gttaatacaa
    12181 caattaaaat gaaaaaatac atatgtgtag gccatagcaa taagtgtctt tgaaatataa
    12241 atttgagagc ttttgataaa atttggtata catatatatt ttatactacg gatatataaa
    12301 tctatctaca tatataaaga gattgtaagt aggtttgtgt atataaaaat agatttatat
    12361 ttcataaatg tactttttat ttgtattacc tttattttat ctaagctctc attttattat
    12421 ctaatcttcc tttttactgg ttttattaat agagatgcaa ttatcaacac aacacttcca
    12481 agtatcagcc aatatttctc atcaaaacta ccttgactca tagacattat aaaaaatttt
    12541 ccaacatact tgcctttagt catcatattt aaaattaaat atcctataga tatcatataa
    12601 cctatgattg tattattaaa taaatttgag aaaaacattc ctaaacttcc tataaacata
    12661 gctgatgcga aacttccaat aatatactca actactggaa aattacatcc aagatatatt
    12721 aaaacattta caaaacctat gattaatacc actataccta taattgacat cagtatccta
    12781 attaattgta caataacttg agataatgct tttgaagata ctatctcatc aatttctttt
    12841 gattgctcta gcgaaaatac aggtaccaac attactatcc ctattattgc aacataattt
    12901 tctaaacata tagctgttga aattctgtct aaattagcta ctccttgtat tagaggaatc
    12961 atacatagca atataattga acatattaaa ttagttaaag tgcttaattt gaagttttct
    13021 tttattagaa ctaaatagtt ttgaaaactt tgcccaaaca tcaagattcc cccttctttt
    13081 ttgctcatat aagaatatag ctaacaaaac aagcaccaat gcttccaagc ttatcacaat
    13141 tctattaatc ataatttgat tgaagttttg tataataata tctccattta atacactatt
    13201 atgtcttatc attagtccca ttgttgaata atcacctttg agtcctgtag aatttatact
    13261 gtaaaaccac caaattaatt gcacaataat tgctactggt gtatctgtta atatagtaat
    13321 actcattcct acagctgtaa ctatcataag agttggtagt atccaccata atgtatattt
    13381 tataaatgct aagttatcaa tagatatacc tttatcttta gcaaagaaaa tcaaaggaag
    13441 taaatctttc atacctaaaa ttaatacagg caatatcatc ataaagacaa gtgcaaaata
    13501 tcttgataaa actattttgc atgaagatac ttgttttgaa taaataatct ctctcattct
    13561 tgaacgctta tctttaagtg acataaaaac tgccacaaat actggaaata tacttaaaac
    13621 tatacctata taatcgcaaa aaattcttgc atacccatta ctaactttat ctttttgtat
    13681 tgtatagttg taattcttca tagcttcatc ataggtaact ggaactactc caaatctttg
    13741 taacttgtca aaagcatatg cagaccctcc tcctaaaatg tcgtctactc tttgcattat
    13801 ttcttcaaat ctttcaagag atactttaga ataatctatt tttatacttt catcagtttt
    13861 ccaaagtgaa tttatttcgc taatactttt accagttatt tcttctatat atttttctat
    13921 ggtcttcgtt ttattttggt ctaattttat atacttaact acccctgttg gatacgttgt
    13981 atatgtgttt ttttgatatt ctctaattag gtttatagtt gcatttggaa tgactttttc
    14041 tgttttcata gattcttttt gaccatatgg atattgattg tgtacagagt aatattcctc
    14101 aatattctct actttttgtg gagcaactaa tggatttcca tcattaggaa tatttttact
    14161 tacatcattt gaaactgaac ttccaagttg agaaatatag aaaaaaacta aaactacaat
    14221 aaaaatataa tatatcatac tctttaatat atttttacat tcttttataa atagattcat
    14281 atattatctc ctcccattat aagcatatag ccatcttcaa tagttggatt acaatttact
    14341 gctgtctcaa aaggtttatc atctgatata atcctaagta tagcctttcc accatgagtc
    14401 aacattccta taactataaa tctacttttt atattttcaa tatctttttt atctacttca
    14461 atactatata ctttcccttc agctagtttt gctaatgctt ctgttgagcc attgtatatg
    14521 acttttccac tattcaatat agctacgttt tcacatgtag cttctatatc tccaacaata
    14581 tgtgtagata aaataacgat tctatcattt gcaatttcgc atagtaaatt tctaaatctt
    14641 atacgttctt ctgggtcaag acctgctgtc ggctcatcta ctattaaaac tctaggatta
    14701 tgaattaatg cttgtgctat cccaagcctt ctattcatac ctccagataa agattttact
    14761 ttcacatttt gataattagt aaggtttact ttgcttaata actttgctat aatttttctt
    14821 ctttttctta gtggtatatc cgataaaact gctaaataat ccattgcttt atatactgtc
    14881 atgttaggat acattgaaaa atcttgtggc aaataaccaa ccatatttct aatttcctta
    14941 gtattctcaa taggaactcc acacatatgt attgaacctt ctgtttttga taataaagtg
    15001 gctaaaattc tcataaatgt ggtttttcct gctccatttc ttcctaaaag accaaacata
    15061 ccactgtcga tttcaagatt tatattatca agtgcttgtt ttttcccaaa tcttttgcta
    15121 agattggata ctgctatttt catttccata tataaataca cccccagaaa caattttata
    15181 gaattttatt tttataaatt tttactgtat tttcataata aattctaaaa cttaagatat
    15241 tatttataaa tttctaaatt ttttctaaag attttaattt ttctgttttt aattaaatta
    15301 aagtatcttt gtttctgaaa ttttttaagt ttatgaagtt ataatttaat atatatttat
    15361 tttatttgtg agtctatttt tatatataat gaaaaatgtg ataagtatcc aaaagaatta
    15421 ctggatataa taagataggg tatttagcct tttaagataa ataaaaatat ctgcaactat
    15481 atattgcaaa aatttaaaac taatttatat atgctaatat aaatatttat aaagacataa
    15541 gacaaattta cctacagatt taaatttaac ttatatattt taaaaggcta atataatatg
    15601 tattttcttc tatacaatca aaaggcttca tatctaagat atgtgatgac actaatattc
    15661 acaattttta gtaattatca cattataaaa aatattacag ctagtccatc attagatgct
    15721 tcttgtataa actttttaag ctcaattaga tttgcccata catattcaaa aaaatcatct
    15781 tcactctcat cattcataac aggataaata ttattttcta acatctcatt aatattaaat
    15841 ctttttctaa atgcttgttc ttccaaactg ttcattgctt ttgatagttt ttttacatca
    15901 tttgctgtaa tcaacatgac aggaaattct ccatcaattt ccataagtat gtttccactt
    15961 agtactaatt tgctaaatat attatcatca tctccaccaa aaggacaacc tgtcaaagta
    16021 aagtgaatgg catgccatgc tttatcaata ttgatagtac tattttcgtt ggcatcttca
    16081 aaaacaaaat cttgtaaatt ttcttctgct tgctgtaatt taaaaacatt ctcttcactt
    16141 attttagtat aacatcctat catccccata attacattcc tcctaagtag cgttttttta
    16201 attgtaactt ataattaaac ttagttacaa taaaatatat tgagaaaagt attatttcat
    16261 cttaaattta aatacctata ttatcaacta aaattctgtg tttatagcgt aagtattatt
    16321 attttttcct aaaaatcaaa tgaatcagaa gttctatagg caatattgac tataaataag
    16381 aactattact tttaaaaaaa atttaagaaa ttatactgta gaatcatgct ctacttatta
    16441 gcttcaaata aaaaataaat catgttctca aattaaataa taaataacaa taaatttaaa
    16501 ttttaaacta taagagtttc tgaagtgtta ataagcatac caataattat atgtgtaaga
    16561 atttgattta atagatatga ataattt
//
LOCUS       DAMKNB010000080        15979 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.085, whole genome shotgun sequence.
ACCESSION   DAMKNB010000080 DAMKNB010000000
VERSION     DAMKNB010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 15979)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15979)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15979
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.085"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            248..397
                     /gene="rpmG"
                     /locus_tag="PC494_002890"
     CDS             248..397
                     /gene="rpmG"
                     /locus_tag="PC494_002890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004402360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HDF3913374.1"
                     /translation="MRVKVTLACTECKQRNYNTTKNKKNNPDRIELQKYCRFCKKHTT
                     HKETK"
     gene            423..644
                     /gene="secE"
                     /locus_tag="PC494_002891"
     CDS             423..644
                     /gene="secE"
                     /locus_tag="PC494_002891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HDF3913375.1"
                     /translation="MAAQKNDGAKTKKRFSLFGYLKETKQELKRVTWPTKKELFKNTS
                     IVLTVVISCTILVWGIDTILSGALALLLK"
     gene            664..1206
                     /gene="nusG"
                     /locus_tag="PC494_002892"
     CDS             664..1206
                     /gene="nusG"
                     /locus_tag="PC494_002892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination factor
                     NusG"
                     /protein_id="HDF3913376.1"
                     /translation="MSELQEASWYVVHTYSGHENKVKATIEKAVKTRGMEDCIRQVVV
                     PTEEVVETTKTGKEKTRQRKVYPSYVLVKMIITDESWYVVRNTKGVTGFVGPGSKPVP
                     LSEDEVKAMGIDTTDPKVVNSDIDFEIGDTVKVSQGPFSGQIGNIEEIDLENREVKVC
                     INAFGKRTLFVIELEGIEKI"
     gene            1245..1670
                     /gene="rplK"
                     /locus_tag="PC494_002893"
     CDS             1245..1670
                     /gene="rplK"
                     /locus_tag="PC494_002893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012158357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HDF3913377.1"
                     /translation="MAKKVIGQIKLQIPAGKATPAPPVGPALGQHGVNIMGFTKEFNA
                     KTADQAGMIIPVVITVYQDRSFSFITKTPPAAVLIKKALNLKSGSGEPNKKKVAKMTS
                     AQVREIAELKMPDLNAASVEAAMSMIAGTARSMGVVIED"
     gene            1741..2439
                     /gene="rplA"
                     /locus_tag="PC494_002894"
     CDS             1741..2439
                     /gene="rplA"
                     /locus_tag="PC494_002894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HDF3913378.1"
                     /translation="MAKKGKRYAGALQKVDRTKFYDASEALTLVSDIAGAKFDETVEA
                     HIKLGVDSRHADQQVRGAVVLPHGTGKTKRVLVFAKGEKAKEAEQAGADFVGAEELVQ
                     KIQGENWFDFDIVVATPDMMGVVGRLGRVLGPKGLMPNPKSGTVTFDVAKAIDEIKAG
                     KVEYRLDKTNIIHVPVGKVSFGGEKLTENFTALMDAIIKAKPAAAKGQYLRSITVASS
                     MGPGVKINPARTAE"
     misc_feature    2491..2619
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            2662..3168
                     /locus_tag="PC494_002895"
     CDS             2662..3168
                     /locus_tag="PC494_002895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HDF3913379.1"
                     /translation="MRKAIEIKSEVVSEIVEKLQKSSAAVVVDYKGLTVEEVTELRKQ
                     MREAGVDYKVYKNTLVRRAAKEVGIEQFNDELLVGTNAIAFGYDDPVAPARILKGFMD
                     SHPKMKLKMGIVEGAFYDESKIVEMANIPSREVLIAKLLGSLKAPVSNFAYLIDAIAK
                     KAEGQEEA"
     gene            3226..3591
                     /gene="rplL"
                     /locus_tag="PC494_002896"
     CDS             3226..3591
                     /gene="rplL"
                     /locus_tag="PC494_002896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000159736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HDF3913380.1"
                     /translation="MTIEQILEAIENMKVLELNELVKAAEEKFGVSASAPVMVAGAAA
                     GGPAAEEKTEFDVVLTDVGSSKVGVIKAVREITGLGLKEAKEVVDNAPKTVKEGASKE
                     EADQIKEKLEAAGAKVEVK"
     gene            3983..4771
                     /locus_tag="PC494_002897"
     CDS             3983..4771
                     /locus_tag="PC494_002897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HDF3913381.1"
                     /translation="MEKLQGKIAVVTAATKGIGLASAEILAKNGATVYLAARSEELAN
                     EVINKISAEGGCAKFVYFNAREEETFTSMIEEVVKKEGKIDILVNNFGSTNPSLDKDL
                     VTGDTDNFFDTVNTNLKSVYLPCKAAIPHMIKNGKGSIVNISSIGSVLPDLSRIAYCV
                     SKAAINSLTQNIATQYAKDNVRCNAVLPGLIATKAALDNMSPEFIKEFLKHVPLNRIG
                     EPDDIAKAVLFYASDDSSFITGDLLEVAGGFGLPTPQFADNILG"
     gene            5242..8958
                     /gene="rpoB"
                     /locus_tag="PC494_002898"
     CDS             5242..8958
                     /gene="rpoB"
                     /locus_tag="PC494_002898"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HDF3913382.1"
                     /translation="MPHPVTIGKRTRMSFSKIKEIADVPNLIEIQVDSYEWFLKEGLK
                     EVFDDISPIEDYTGNLILEFVDYSLDDKPKYDIEECKERDATYCAPLKVKVRLINKET
                     GEIKEQEVFMGDFPLMTERGTFVINGAERVIVSQLVRSPGVYYAEERDKTGKRLISST
                     VIPNRGAWLEYETDSNDVISVRVDRTRKQPVTVLLRALGIGTDAEIIDLLGEDERLSA
                     TLEKDNTKTVEEGLVEIYKKLRPGEPPTVESASSLLNALFFDPKRYDLAKVGRYKFNK
                     KLALCYRIMNKISAEDIINPETGEVFVKAGEKISYDLAKAIQNAGINVVNLLMDDDKK
                     VRVIGNNFVDIKSHIDFDIDDLNIKEKVHYPTLKEILDGYSDEEEIKEAIKSRIKELI
                     PKHILLDDIIASISYEFNIFYNIGNIDDIDHLGNRRIRSVGELLQNQVRIGLSRMERV
                     IKERMTVQDMEAITPQALVNIRPVSAAIKEFFGSSQLSQFMDQTNPLSELTHKRRLSA
                     LGPGGLSRERAGFEVRDVHHSHYGRMCPIETPEGPNIGLINSLGTYAKINEFGFIESP
                     YRKFDKETSTVTDEIHYLTADEEDLFVRAQANEPLTEDGKFVNHRVVCRTVNGAVEMV
                     PESRVDYMDISPKQVVSVATAMIPFLENDDANRALMGANMQRQAVPLVRREAPIIGTG
                     IEYRAAKDSGAVVVARNSGIAERVTADEIIIKREDGNRDRYNLLKFKRSNSGTCINQT
                     PIINKGDQIIKGDVIADGPATDLGEVALGRNCLIAFMTWEGYNYEDAILINERLVKED
                     RLSTIHIEEYECEARDTKLGPEEITRDIPNVGDSAIKNLDDRGIIRIGAEVDSGDILV
                     GKVTPKGETELTAEERLLRAIFGEKAREVRDTSLKVPHGESGIIVDVKVFTRENGDDL
                     SPGVNELVRCYIAKKRKIKVGDKMAGRHGNKGVISRVLPEEDMPFMENGTPLDIILNP
                     QGIPSRMNIGQVLEVHLGLAAKTLGWYVATSVFDGANEYDIMDALEEAGYPRDGKLTL
                     YDGRTGESFDNRITVGYMYYLKLHHLVDEKLHARSTGPYSLVTQQPLGGKAQFGGQRF
                     GEMEVWALEAYGAAHILQEILTVKSDDVVGRVRTYEAIVKGENIPEPGIPESFKVLIK
                     ELQSLCLDVKVLTDEDQEIEVRESVDEDDTIGEFELDVVNHMGEVEESNIIEEIEDDF
                     AENAEDEDIENLEEFTEDDLFEEEIDFDSDDFDM"
     gene            9000..12485
                     /gene="rpoC"
                     /locus_tag="PC494_002899"
     CDS             9000..12485
                     /gene="rpoC"
                     /locus_tag="PC494_002899"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HDF3913383.1"
                     /translation="MFELNNFESIKIALASPEKIRQWSRGEVKKPETINYRTLKPEKD
                     GLFCERIFGPQKDWECHCGKYRRVRYKGVVCDRCGVEVTKSKVRRERMGHIELAAPMS
                     HIWYFKGIPSRMGLLLDMSPRSLEKILYFASYVVVDPGETGLNEKQLLTEKEYRTALE
                     KYGYTFTVGMGAEAVKTLLQNIDLEQQSKDLRAELKDSTGQKKVRTIRRLEVVEAFKK
                     SGNKPEWMILDAIPVIPPDLRPMVQLDGGRFATSDLNDLYRRVINRNNRLKRLLELGA
                     PDIIVRNEKRMLQEAVDALIDNGRRGRPVTGPGNRPLKSLSDMLKGKQGRFRQNLLGK
                     RVDYSGRSVIVVGPELKFYQCGLPKKMALELFKPFVMDKLVKEGYAHNIKSAKSIVEK
                     VKPEVWDVLEDVIKSHPVLLNRAPTLHRLGIQAFEPILVEGKAIKLHPLVCTAYNADF
                     DGDQMAVHVPLSVEAQAEARFLMLSVNNILAPKDGSPITTPSQDMVLGCYYLTIEAQD
                     GAKGTGMVFKDFNELLLAYYNKSVHLHALVKLKVTLEDGRSSLVESTVGRFIFNENIP
                     QDLGFVDRKENPFALEVDFLADKKSLGKIIDKCFRKHGNTETAELLDYIKALGFKYST
                     LGGITVAVDDMSVPEEKKVFIAEAEAKVDKYEKAYRRGLISDEERYEKVIETWTETTD
                     KVTDALMGGLDRLNNIYIMAHSGARGSKNQIRQLAGMRGLMANASGKTVEIPVKSNFR
                     EGLSVLEYFTSSHGARKGLADTAIRTAESGYLTRRLVDVSQDVIVREIDCGTEDTTEI
                     YAIKEGNEVIEEIYDRIVGRYTIDPILNPETGEVIVEADSMIQEDEAETIVALGIEKI
                     RIRTVLNCKTNHGVCSKCYGRNLATGKEVNIGEAVGIIAAQSIGEPGTQLTMRTFHTG
                     GVAGADITQGLPRVEELFEARKPKGLAVITEVSGRVEIDETGKRKEVNVIPEEGETQT
                     YVIPYGSRLKVKQGQMLEAGDPLTQGFINPHDIVRVNGVKGVQEYIVKEVQRVYRLQG
                     VDVNDKHIEVIVRQMLSKVKVEDPGDTDLLPGGYEDVLTFNECNKDAIDKGLRPAVAK
                     RVLLGITKASLATDSFLSAASFQETTRVLTEAAIKGKEDHLIGLKENVILGKLIPAGT
                     GMKKYRNIAVEKIED"
     gene            12774..13196
                     /gene="rpsL"
                     /locus_tag="PC494_002900"
     CDS             12774..13196
                     /gene="rpsL"
                     /locus_tag="PC494_002900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HDF3913384.1"
                     /translation="MPTINQLVRKSRKALEKKSTAPALQKGYNSLNKKVTDASAPQKR
                     GVCTSVKTVTPKKPNSALRKVARVRLTNGIEVSAYIPGEGHNLQEHSVVLIRGGRVKD
                     LPGVRYHILRGTLDTAGVDKRRQSRSKYGAKRPKEAKK"
     gene            13320..13790
                     /gene="rpsG"
                     /locus_tag="PC494_002901"
     CDS             13320..13790
                     /gene="rpsG"
                     /locus_tag="PC494_002901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001137493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HDF3913385.1"
                     /translation="MPRKGNIPKREVLPDPMYGSKVVTKLINNLMVDGKKGKSQRIVY
                     DAFAIVAEKTGEEALEVFNKAMDNIMPVLEVKARRVGGANYQVPIEVRPERRQTLGLR
                     WLVKYTRARGEKGMVEKLAKEIMDAANNTGASVKKKEDTHKMAEANKAFAHYRW"
     gene            13839..15905
                     /gene="fusA"
                     /locus_tag="PC494_002902"
     CDS             13839..15905
                     /gene="fusA"
                     /locus_tag="PC494_002902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HDF3913386.1"
                     /translation="MARKFPLERTRNIGIMAHIDAGKTTTTERILFYTGQTHKIGETH
                     EGASQMDWMEQEKERGITITSAATTASWKDHRINIIDTPGHVDFTVEVERSLRVLDGS
                     VAVFCAKGGVEPQSENVWRQAETYGVPRIAFVNKMDILGADFYNVVSMMKSRLNSNAV
                     PMQLPIGKEDSFIGIIDLLKMDAVIYKDDLGVEMEETDIPEDMKELAAEWREKLVESV
                     AETDEELMMKYLEGEELTIDELKVAIRKATIACEMNPVFCGTAYRNKGVQLVIDAVLD
                     YLPAPTDIPAIKGILADGEEAERHSSDEEPFSALAFKIMTDPFVGKLAFFRVYSGTLE
                     SGSYVLNATKNKRERIGRILQMHANTREEITKVYAGDIAAAVGLKDTTTGDTLCDPAN
                     PIILESMEFPEPVISVAIEPSSKAAQEKMGIALQKLAEEDPTFTVKTDQETGQTIISG
                     MGELHLEIIVDRLLREFKVEAKVGAPQVAYRETITQPVDVEYKYSKQSGGRGQYGHVK
                     IRVAPQEPGEGYKFTNKTVGGSVPKEYVGPVDMGIQGAMQSGIVAGYPVVDVAVELYD
                     GSYHEVDSSEMAFKMAGSMAFKDAMKKGNAVLLEPYFKVEVVTPEDYMGDVMGDLNSR
                     RGLIQGMEARSGAQVINAFVPLSEMFGYSTDLRSSTQGRATYTMIFDHYEQVPASVAK
                     KIAEGK"
BASE COUNT         6255 a         1987 c         3252 g         4485 t
ORIGIN      
        1 ctttactaaa ctgatggatt aaaaggaata acaaaaagag gggttatgct cctctttttt
       61 taacatagaa atacaaaaac attgacacag cataggattt tgtgataact tatacaaggt
      121 aatgattata ggaagttaat aatatcttga atactgtaga tttttaataa atacatattt
      181 taaagatatt atattcacat atattaacaa tatatattat tgtattacaa agttggaggt
      241 gtatcagatg agagttaaag taactttagc atgtacagag tgtaagcaaa gaaactacaa
      301 cactactaag aataagaaaa acaatccaga cagaatagaa ttacaaaaat attgtagatt
      361 ctgtaaaaag catacaactc ataaagaaac aaaatagttt tttataagga tgtgagtatg
      421 gaatggctgc ccaaaaaaat gacggtgcaa aaactaaaaa aaggtttagt ttgtttggat
      481 acttaaaaga aactaaacaa gaattaaaaa gagttacatg gccgacaaaa aaggaactgt
      541 ttaaaaacac aagtatagtt ttaactgtag ttatttcatg cactatatta gtatggggta
      601 tagacactat attatctggt gcactagcgt tattactaaa atagacgaaa agaggtaagt
      661 taaatgtcag aattacaaga agcaagttgg tatgtagttc atacctattc gggacatgaa
      721 aataaagtta aagctacaat tgagaaagca gttaaaacaa gaggtatgga agactgcata
      781 agacaagtag ttgttccaac agaagaagta gtggaaacta ctaaaactgg aaaagaaaaa
      841 actagacaac gtaaagttta tccaagttat gttttggtta aaatgataat aactgatgaa
      901 tcttggtatg tagtaagaaa tactaaggga gttacaggtt tcgttggacc tggttcaaaa
      961 ccagtgccat taagtgaaga cgaagtcaaa gctatgggga tagacacaac agaccctaaa
     1021 gtagtaaata gcgatattga ttttgaaata ggagatacag taaaagtatc tcaaggacca
     1081 tttagtggac aaataggtaa catagaagaa attgacttag aaaatagaga agtcaaagta
     1141 tgcataaatg catttggtaa aaggactcta tttgtaatag agcttgaagg tatagaaaaa
     1201 atctaatact atattataga aaaatctgag gaggtgcgct caaaatggct aaaaaagtta
     1261 taggtcaaat aaaattacaa atacctgcag gaaaggctac tccagcgcca ccagttggac
     1321 cagcattagg acaacatggt gttaatataa tgggattcac aaaagaattt aatgctaaaa
     1381 ctgcagatca agctggaatg ataataccag ttgttataac tgtatatcaa gatagatcat
     1441 tcagttttat aacaaaaact ccaccagctg cagttttaat taaaaaagca ttaaacttaa
     1501 aatcaggttc tggagaacca aacaagaaaa aagttgctaa aatgacttca gctcaagtaa
     1561 gagaaatagc tgaattaaag atgcctgact taaatgctgc atcagtagaa gctgctatga
     1621 gtatgatagc tggtactgct agaagcatgg gtgttgtaat cgaagactaa ttaaaagata
     1681 cacttttttt tataaagtgg gaggctagaa gccgaaatta accacgagga ggaaaataaa
     1741 atggctaaaa aaggtaaaag atatgcaggt gcattacaaa aagtagatag aactaaattt
     1801 tatgatgcat cagaagcatt aacattagtt tcagatatag ctggagctaa atttgatgag
     1861 acagtagaag cacacattaa attaggtgtt gactcaagac atgctgacca acaagtaaga
     1921 ggtgcagttg tattacctca tggaactggt aaaacaaaaa gagttttagt ttttgctaaa
     1981 ggtgaaaaag ctaaagaagc tgaacaagct ggtgctgact ttgtaggagc tgaagaatta
     2041 gttcaaaaaa tacaaggtga aaactggttt gactttgata tagtagttgc tactccagat
     2101 atgatgggtg tagtaggtag attaggtaga gtattaggac ctaaaggttt aatgccaaac
     2161 cctaaatcag gaacagttac atttgatgta gctaaagcta tagatgaaat aaaagctggt
     2221 aaagttgaat acagattaga caaaactaac ataatacacg ttccagtagg aaaagtatca
     2281 tttggtggag aaaaattaac tgaaaacttt actgcattaa tggatgctat aataaaagct
     2341 aaaccagctg ctgctaaagg acaatattta agaagtataa cagtagcttc ttcaatggga
     2401 cctggagtta aaataaaccc agcaagaaca gctgaataat aaaactgttg acacaggttg
     2461 acaaaaatgt tattatatca cttgtcaatg taaaaaagaa tagatttgcc gtagatagtg
     2521 ggtgcgagag cttaatatcc cgccgaggtt ttagataaat tgagattact aaagcttttg
     2581 atgtctactt ttggcaacaa aagcttttta taatgttgcg gtaaatacta agcctatttg
     2641 gtgaaggagg tgcacatcta tatgagaaaa gctatagaaa ttaaatcaga agttgtttct
     2701 gagatagttg aaaagttaca aaaatcttct gctgctgttg ttgtagatta caaaggatta
     2761 acagttgaag aagtaactga gttaagaaaa caaatgagag aagctggtgt agattacaaa
     2821 gtatacaaaa atactttagt tagaagagca gctaaagaag ttggtataga gcaatttaat
     2881 gatgaattat tagttggaac taatgccata gcatttggat atgatgatcc agttgctcca
     2941 gctagaatat taaaaggatt catggattct catccaaaaa tgaaattaaa gatgggtatt
     3001 gtggaaggtg cattctatga tgaatctaag attgttgaaa tggctaacat accatcaaga
     3061 gaagttctta tcgctaaatt acttggtagc ttaaaagctc cagtatcaaa cttcgcatac
     3121 ttaatagatg caatagcgaa aaaggcagaa ggtcaagaag aagcttaatt gcttaactaa
     3181 aaaattataa atattaattt gaaataaaat tcggaggtgc taaaaatgac aatagaacaa
     3241 atattagaag ctatagaaaa tatgaaagtt ttagaattaa atgaattagt taaagctgct
     3301 gaagaaaaat tcggtgtatc agcttcagct ccagtaatgg tagctggtgc agctgctggt
     3361 ggaccagctg ctgaagaaaa aactgagttt gatgtagtat taactgacgt tggttcttca
     3421 aaagttggag ttataaaagc agttagagaa ataacaggat taggattaaa agaagctaaa
     3481 gaagtagttg acaatgctcc taagacagtt aaagaaggag cttctaaaga agaagctgat
     3541 caaataaaag agaaattaga agctgctgga gctaaagtag aagttaagta gtttctttaa
     3601 aaagataccc attgggtatc tttttttatt tataaaaaac tataaagaaa gtatttggaa
     3661 ttataaagaa agtattttta taaaataaaa aaaatttata taatagtact aaattaaggg
     3721 tatcatatat ggtgtaatgg tattttaatt taacattatt atcaaattaa aatataaaca
     3781 attgttgtaa tgtctatata taaagtatat aattaaacta aaatgtaaaa ttttacattt
     3841 tagtttaaaa aaatacacga gtgttttgta aataaaatgt aataaataat taattaacaa
     3901 atataaattt taaaataagt tagatattta gaaaaatcga aatttgtagg atttaaagga
     3961 catattcaag gaggagttaa taatggaaaa attacaagga aaaattgcag tagttactgc
     4021 agcaacaaaa ggtattggat tagcatcagc agagatatta gcaaaaaatg gagcaactgt
     4081 gtacttagca gctcgttcag aagaattagc taatgaagtt ataaataaaa taagtgcaga
     4141 aggtggttgt gctaagtttg tttactttaa tgctcgtgaa gaagagacct ttacctcaat
     4201 gatagaagag gtagttaaaa aagaaggtaa gatagatata cttgtaaaca attttggttc
     4261 aacaaaccct tctcttgaca aagaccttgt aactggggat acagataatt tctttgacac
     4321 agtaaatact aatttaaaaa gtgtgtattt accatgtaaa gcagcaattc ctcatatgat
     4381 aaagaatgga aaaggaagta tagtaaatat atcaagtata ggttcagtat tacctgattt
     4441 atctagaata gcttactgtg tatcaaaagc agcaatcaac tcattaactc aaaacatagc
     4501 tacacaatat gctaaagaca atgttagatg taatgctgta cttccagggc ttattgcaac
     4561 taaagcagca ttagacaata tgtctccaga gttcataaaa gaatttttaa agcatgttcc
     4621 tttaaatcgt ataggggaac cagatgatat agcaaaagct gttctattct atgctagtga
     4681 tgactcatca tttataacag gggatttact tgaagttgca ggaggatttg gtttacctac
     4741 tccacaattt gcagataata tattaggata attaaattac taatatgcaa tgaaagctta
     4801 tgcattagtt gtagtagaaa tgatattttt ataaagacca tagatataat ttatattgga
     4861 aaggtttgag gttcaaaatt ccaagttaaa tttatttatg gtctttattt tgtatatttt
     4921 aataaattgt atatatttgt ataaatgtaa ttatttacaa tcattttaat atggaattat
     4981 aattaaatag gggggatggt acttgtataa aattttttat agaaaattag acctataaat
     5041 gaaaaatatg gattttatat tggaaaattg tacataatac ataatatatg cttaaaataa
     5101 tttacaaaaa atcaaaaata atgcatagtt tacatataag ataaaaaata tattgaaaaa
     5161 tacttgacat tatgctaaaa ttattagatg cgttagaatg aactattgtt ttatttttaa
     5221 ttattgagag gtgaaaagtg aatgccacat cctgtcacga taggtaaaag aactagaatg
     5281 agcttttcta aaattaagga aatagctgat gtgccaaatc ttatagaaat tcaagtagat
     5341 tcctatgagt ggtttttaaa agaaggttta aaagaagtgt ttgatgatat ttcaccaata
     5401 gaagattata ctggtaatct tatattggaa tttgtcgact attctctaga tgataaacca
     5461 aagtacgata tagaagagtg taaagagaga gatgctacat attgtgcacc tctaaaggtt
     5521 aaggtaagac ttataaataa agaaacaggt gagataaaag aacaagaagt gtttatgggt
     5581 gacttccctt taatgacaga aagaggaact ttcgttataa atggagcaga aagagttata
     5641 gtaagtcaat tagttagatc tcctggtgtt tactatgcgg aagaaagaga taaaacaggt
     5701 aagagattga tttcatctac tgtaattcct aatagaggag catggttaga atatgaaaca
     5761 gattctaatg atgtaatatc tgtaagagtt gatagaacaa gaaaacaacc agttacagtt
     5821 ttacttagag ctttaggaat aggaacagat gcagagataa ttgacctttt aggagaagat
     5881 gagagattat ctgctacatt agaaaaagat aatactaaga cagtagaaga aggtcttgta
     5941 gagatataca aaaaattaag accaggtgaa cctcctactg tagaaagtgc atcatcttta
     6001 ttaaatgctt tattctttga cccaaaaaga tatgacctag caaaagttgg tagatataaa
     6061 ttcaataaga aacttgcttt atgttataga ataatgaata aaatttcagc agaagacata
     6121 ataaatccag aaactggaga agtatttgta aaagctggag aaaaaataag ctatgatttg
     6181 gctaaagcca tacaaaatgc aggtataaat gtagtaaatc tactaatgga tgatgataaa
     6241 aaagttagag ttataggaaa taattttgtg gatattaagt ctcacattga ttttgacata
     6301 gatgatttaa acataaaaga aaaagtacat tatccaactt taaaagaaat tttagatgga
     6361 tatagtgatg aagaagaaat aaaagaggct ataaaatcaa gaattaaaga acttatacca
     6421 aaacatatat tattagatga tataatagct tcaataagtt atgagttcaa tatattctat
     6481 aatataggaa atattgatga tatagatcac ctaggaaaca gaagaataag atctgtaggt
     6541 gaattgttac aaaatcaagt tagaattggt ctttcaagaa tggaaagagt tataaaagaa
     6601 agaatgacgg ttcaagatat ggaagctata acgcctcaag cgttagttaa cataagacca
     6661 gtttcagctg caataaaaga attttttggt agttctcagt tatctcagtt catggatcaa
     6721 acaaatcctc tatctgagtt aacgcataag agaagattat cagcccttgg gcctggaggt
     6781 ctttcaagag aaagagctgg attcgaagtg cgtgacgttc accattcaca ctatggtaga
     6841 atgtgtccaa tagagactcc agagggacca aatatcggtc ttataaactc tctaggaact
     6901 tatgcaaaaa taaatgaatt tggatttata gaatcaccat atagaaaatt tgataaagaa
     6961 acatcaacag ttactgatga aatacattat ttaactgctg acgaagaaga tttattcgta
     7021 agagctcagg caaatgagcc attaacagaa gatggtaaat tcgtaaacca tagagttgtt
     7081 tgtagaactg taaatggtgc tgttgaaatg gttcctgaaa gtagagtaga ttacatggat
     7141 atatctccta agcaggttgt atctgttgcc actgctatga tacctttctt agaaaatgat
     7201 gatgccaacc gtgcccttat gggagcgaac atgcagcgtc aggcagtgcc tctagttaga
     7261 agagaagcac caattatagg aactggtata gaatacagag cagcaaaaga ctctggagca
     7321 gttgttgttg ctagaaattc tggtatagca gaaagagtaa cagcagatga aataattata
     7381 aaaagagaag atggaaacag agatagatat aatctactta agtttaaacg ttcaaactca
     7441 ggtacttgta taaatcaaac acctataata aataagggtg accagataat aaaaggtgat
     7501 gttatagcag atggtccagc aactgattta ggagaagttg cacttggaag aaactgtctt
     7561 atagcattca tgacttggga aggttataac tacgaggatg ctatattaat aaatgaaaga
     7621 ttagttaaag aagatagatt atcaacaatt catatagaag aatatgaatg tgaagctaga
     7681 gatacaaaac tagggccaga ggaaataact agagatatac ctaatgttgg agatagtgca
     7741 attaagaatt tagatgacag aggtataata agaataggtg cagaagtaga ctcaggtgat
     7801 atattagttg gtaaagtaac tccaaaagga gaaactgaac ttactgctga ggaaagatta
     7861 cttcgtgcaa tatttggaga aaaggctaga gaagttagag atacttcact taaagtgcct
     7921 catggtgaat ctggtataat agttgatgta aaagtattta ctagagaaaa tggagatgat
     7981 ttatctccag gagtaaatga attagtaaga tgctatatag ctaaaaagag aaaaataaaa
     8041 gttggagata aaatggctgg tcgtcatggt aataaagggg ttatctcaag agtattacct
     8101 gaagaagata tgccattcat ggaaaatgga acaccactag acataatact taacccacaa
     8161 ggtataccat cacgtatgaa cattggtcag gttttagaag ttcatttagg acttgctgct
     8221 aagacattag gatggtatgt agcaacatca gtattcgatg gtgctaatga gtatgacata
     8281 atggatgctc ttgaagaagc tgggtatcct agagatggta aattaacttt atatgatggt
     8341 agaacaggtg agtcttttga caacagaata actgttggat atatgtacta cttgaaacta
     8401 catcacttag tagatgaaaa actacatgca agaagtactg gaccatactc attagttact
     8461 caacagccac taggtggtaa agcacaattt ggtggacaaa gatttggaga gatggaggtt
     8521 tgggctctgg aagcatatgg agctgctcac atacttcaag aaatacttac tgttaagtct
     8581 gatgacgttg taggtcgtgt tagaacatat gaagctatag ttaaaggtga aaatatacct
     8641 gaaccaggaa tcccagaatc atttaaggtt cttataaaag aacttcaaag tttatgctta
     8701 gatgtaaaag tattgacaga tgaagaccaa gaaatagaag taagagaatc tgtggatgaa
     8761 gatgatacaa taggtgaatt tgagctagat gttgtaaatc atatgggaga agttgaagaa
     8821 agtaatataa tagaagaaat tgaagatgat tttgcagaaa atgcagaaga tgaggatata
     8881 gagaatttag aagaattcac tgaagatgat ttatttgaag aagaaataga ttttgatagt
     8941 gatgactttg atatgtaaat ttaattaatg taaatctcaa atagaaggga gagaactcct
     9001 tgtttgaatt aaacaatttc gagtcgataa aaatagcatt ggcttctcca gaaaaaataa
     9061 gacaatggtc taggggagaa gttaaaaagc cagaaactat aaattaccgt actttaaaac
     9121 cagaaaaaga tggtcttttc tgtgaaagaa tatttggacc acaaaaagac tgggagtgcc
     9181 actgtggtaa atatagaaga gttagatata aaggtgtagt ttgtgataga tgtggagtag
     9241 aagtaactaa atcaaaagta agaagagaga gaatgggaca tatagagcta gcggctccta
     9301 tgtctcacat ctggtacttc aaaggtatac caagtagaat gggactttta cttgatatgt
     9361 caccaagatc gttagaaaaa atattatact ttgcctcata tgtggtagtt gatccaggag
     9421 agactggatt aaatgaaaaa caattgctta cagaaaaaga atacagaact gctcttgaaa
     9481 agtatggata tacttttact gtaggaatgg gtgctgaagc tgtaaagaca ttactacaaa
     9541 atatagattt agagcaacaa agtaaagacc taagagcgga gttaaaagat agtacagggc
     9601 aaaagaaagt tagaacaata agaagattag aagttgtaga ggcatttaaa aagtctggaa
     9661 ataaaccaga atggatgatt ttagatgcaa taccagtaat accaccagat ttaagaccaa
     9721 tggtacaact tgatggtgga agatttgcga cttcagacct aaatgattta tatagaagag
     9781 ttataaatag aaacaataga cttaaaagat tattagagct tggagctcca gatataattg
     9841 taagaaatga aaaaagaatg cttcaagaag ctgttgatgc attgatagat aatggtagaa
     9901 gaggtagacc tgtaacagga cctggaaata gaccacttaa atctttatca gatatgttaa
     9961 aaggtaagca aggtcgtttc cgtcaaaact tacttggtaa gcgtgttgac tactcaggac
    10021 gttctgttat agttgttgga ccagaactta aattttatca atgtggactt ccaaagaaga
    10081 tggcattaga attattcaag ccatttgtta tggataaatt agttaaagaa ggttatgcac
    10141 ataatataaa aagtgcgaaa tctatagtag aaaaagttaa gccagaagtt tgggatgttt
    10201 tagaagatgt tataaaaagt catccagttc ttcttaaccg tgcaccgact ctacatagat
    10261 taggtataca agcatttgaa ccaatcttag ttgaaggtaa ggctataaaa ctacatcctc
    10321 ttgtatgtac agcttataat gcagactttg atggtgacca aatggcagtt catgtacctt
    10381 tatcagtaga agcacaagca gaagcaagat tcttaatgct ttctgtaaat aatatacttg
    10441 ctcctaaaga tggttcacct ataactactc catctcagga tatggtttta ggttgctatt
    10501 atctaacaat agaagcccaa gatggagcta aaggaacagg tatggtattt aaagacttta
    10561 atgaactatt acttgcttat tacaataaat cagttcatct acatgcatta gtgaaactta
    10621 aggtaacact tgaagatgga agaagttcat tggttgaaag tactgttggt agatttatat
    10681 ttaatgaaaa tatacctcaa gacttaggtt ttgtagatag aaaagaaaat ccatttgcac
    10741 ttgaagttga tttcttagca gataaaaaat ctcttggtaa aataatagat aaatgcttta
    10801 gaaaacacgg aaatacagaa acagctgaat tactagatta tataaaagct ctaggattta
    10861 aatattctac attaggtggc ataacagttg ctgttgatga tatgagtgtc ccagaagaaa
    10921 agaaagtatt tatagctgag gcagaagcta aagttgataa gtatgaaaaa gcatacagaa
    10981 gaggtctaat ctctgatgaa gaaagatatg aaaaagttat agagacatgg acagaaacaa
    11041 ctgataaagt tactgatgct cttatgggtg gactagatag attaaataat atatatataa
    11101 tggcacattc aggagccaga ggttctaaaa accaaattag acagctggca ggtatgcgtg
    11161 gtcttatggc aaatgcatct ggtaaaacag ttgagatacc agttaaatct aatttccgtg
    11221 aaggtttatc agtactagaa tactttacat cttcacatgg tgccagaaaa ggtcttgccg
    11281 atacagctat acgtacagct gaatctggat atttaacaag aagacttgtt gatgtaagtc
    11341 aagatgttat tgtaagggaa atagattgtg gaacagaaga tactacagag atttatgcta
    11401 taaaagaagg aaatgaagtt atagaagaga tatatgatag aattgtagga agatatacta
    11461 tagaccctat attaaatcct gaaactggag aagttatagt tgaggctgat tcaatgatac
    11521 aagaagatga agcagaaact atagtagctt taggaattga aaaaattagg ataagaacag
    11581 ttcttaactg taaaactaat catggagttt gttctaagtg ttatggtaga aacttggcaa
    11641 caggaaaaga agttaatata ggtgaagcag ttggtataat agcagctcaa tctatcggtg
    11701 agccgggtac tcagcttaca atgcgtacat tccatactgg aggagttgca ggagctgata
    11761 taactcaagg tctaccaagg gttgaagaat tatttgaagc tagaaaacca aaaggattag
    11821 ctgtaataac tgaagtatct ggtagagttg aaattgatga aacaggaaag agaaaagaag
    11881 taaatgtaat accagaagaa ggcgagactc aaacatatgt aattccatat ggttctagat
    11941 taaaagttaa gcaaggtcaa atgctagagg ctggagaccc tctaacacaa ggatttataa
    12001 atcctcatga tatagtaaga gtaaatggtg ttaagggagt tcaagaatat atagttaaag
    12061 aagttcaaag agtgtataga cttcaagggg ttgatgttaa tgataagcat atagaagtta
    12121 tagtaagaca aatgctatct aaagtaaaag ttgaagaccc aggagataca gatttattgc
    12181 caggtggata tgaagatgta ttaacattca atgaatgtaa taaagatgct atagataaag
    12241 gtctaagacc agcagttgct aaaagagttt tacttggtat aactaaagca tctcttgcaa
    12301 ctgattcatt cttatcagca gcttctttcc aagaaacaac aagagtatta acagaggcag
    12361 caataaaagg taaagaagac cacttaatag gacttaaaga aaatgttata ttaggtaagt
    12421 taataccagc aggaacagga atgaagaaat atagaaatat agctgttgaa aaaattgaag
    12481 attaatagca tatagagtaa agaaatcttg acaaccatta tttgtggtgt taaaatagta
    12541 aagtgtgttg tttaaaagta cactaagggc ttgaacaagt tcttagtgac ttttagatgg
    12601 caataaatga gaactaaaaa gcatcaagct agaaaagtgc taatatcaca tatttatgtg
    12661 ttatagacat taaattgtaa gtaacgaatg ttacaatcag tcagtatgaa tattcatatt
    12721 gatgtagttg gcggtcactg ataagatcga aaatttggaa ggaggtgcag atgatgccaa
    12781 caattaacca attagttcgt aaaagtagaa aagcgctaga gaagaaatct actgctccag
    12841 cattacaaaa aggttacaac tctttaaata agaaagtaac tgacgctagt gccccacaaa
    12901 aaagaggggt ttgtacttca gtaaaaacag ttactcctaa gaagcctaac tcagctttaa
    12961 gaaaagttgc cagagttaga ttaactaatg gtatagaagt ttctgcttat ataccaggag
    13021 aaggacacaa cttacaagag catagtgttg ttcttataag aggaggaaga gtaaaagacc
    13081 ttccaggggt tagataccat atactaagag gtactctaga tacagcaggt gttgataaga
    13141 gaagacaatc aagatctaaa tacggtgcga agagacctaa agaagctaaa aagtaaaaac
    13201 aattaatgat tgattatagt tcggtgcttt aaatatatat atatttacgg catcacggca
    13261 ttaaatgatt tatgtcgagt acctatgatt taagttaaat aattaaggag ggaagcgaaa
    13321 tgccaagaaa aggtaatatt ccaaaaagag aagttttacc agatcctatg tatgggagta
    13381 aggtagttac taaattaata aataatctaa tggtagacgg aaaaaaagga aagtctcaaa
    13441 gaatagttta tgatgctttc gcaattgttg ctgaaaagac aggagaagaa gctttagaag
    13501 tatttaataa agcaatggat aatataatgc ctgttttaga agtaaaagca agaagagttg
    13561 gtggggcaaa ctaccaagtg ccaatcgaag ttagacctga aagaagacaa acattaggtt
    13621 taagatggct agtaaaatat actagagctc gtggagaaaa aggaatggtt gaaaagctag
    13681 ctaaagagat aatggacgca gctaacaaca ctggagcttc agttaagaaa aaagaagata
    13741 ctcataaaat ggcagaagct aataaagcat ttgctcatta cagatggtag gatatataga
    13801 tatcttataa aattgaggat atcataagga ggataaccat ggctagaaag tttcctttgg
    13861 aaagaactag gaatatagga atcatggctc atatagatgc aggaaaaact actactacag
    13921 aaagaatcct gttttatact gggcaaactc ataaaatagg agaaactcat gaaggagctt
    13981 ctcaaatgga ctggatggag caagaaaagg aaagaggtat aacaataact tctgccgcta
    14041 ctactgcttc atggaaagac catagaataa acataataga tactcctgga cacgtggact
    14101 tcacagttga ggttgaaaga tctctaagag ttcttgacgg ttcagttgct gtattctgtg
    14161 caaaaggtgg ggttgagcct caatcagaaa atgtatggag acaagctgaa acttatggag
    14221 tacctagaat agcttttgta aataaaatgg atatattagg tgcagatttc tacaatgttg
    14281 taagcatgat gaaatctaga ttaaattcta atgcagttcc tatgcaatta ccaataggta
    14341 aagaagattc atttataggt ataatagact tattaaaaat ggatgctgtt atatacaaag
    14401 acgacctagg ggttgaaatg gaagaaacag atataccaga agatatgaaa gaattagctg
    14461 ctgagtggag agaaaaatta gttgaatcag tagctgaaac tgatgaagaa ttaatgatga
    14521 aataccttga aggtgaagaa cttactatag atgaattaaa agttgctata agaaaagcta
    14581 ctatagcttg tgaaatgaac ccagttttct gtggtacagc ttatagaaac aaaggtgttc
    14641 agttagtaat agatgcagtt ttagattact taccagcgcc aactgatata ccagctataa
    14701 aaggtatatt agcagatgga gaagaagctg aaagacattc ttctgatgaa gagccattct
    14761 ctgcattagc attcaaaata atgactgacc cattcgttgg aaaactagcg ttcttcagag
    14821 tttattctgg aacattagaa tcaggttctt atgttttaaa tgcaactaag aataagagag
    14881 aaagaattgg tcgtatatta caaatgcatg ctaatacaag agaagaaata actaaagtgt
    14941 atgctggaga tatagcagca gcagtaggat taaaagatac tactactgga gacacattat
    15001 gtgaccctgc taatccaata atacttgaat ctatggaatt ccctgagcca gttatatctg
    15061 ttgctataga accaagttct aaagcagctc aagaaaaaat gggtatagct cttcaaaaat
    15121 tagctgaaga agacccaact ttcacagtta agactgacca agaaacagga caaactataa
    15181 tatctggtat gggtgaatta cacttagaga taatagtaga tagattatta agagaattta
    15241 aagtagaagc taaagttggt gcaccacaag ttgcatatag agagactata actcaaccag
    15301 ttgatgttga atacaagtac tctaagcaat caggtggtag aggacaatac ggtcacgtta
    15361 agattagagt tgctcctcaa gagccaggtg aaggatacaa attcacaaac aaaactgttg
    15421 gtggatcagt accaaaagaa tatgttggtc cagttgacat gggtatacaa ggagctatgc
    15481 aatctggtat agttgctgga tatccagttg tagacgttgc tgttgagtta tatgatggtt
    15541 cttaccatga ggttgactct tctgagatgg cgtttaagat ggctggttca atggcattca
    15601 aagatgctat gaagaaaggt aatgcagttc ttttagagcc ttacttcaaa gtagaagttg
    15661 ttactccaga agattacatg ggagatgtta tgggtgactt aaactcaaga agaggattaa
    15721 tccaaggtat ggaagctaga agtggtgcac aagttataaa tgcattcgtt ccactttcag
    15781 aaatgtttgg atactcaaca gacctaagat cttcaactca aggtcgtgca acttacacaa
    15841 tgatattcga tcactatgag caagttccag cttcagttgc taagaaaata gctgaaggaa
    15901 aataatttaa aaataattaa taatataaat ataaaaaata atcagctaga tgagagatat
    15961 ctctcatcta gcacaagat
//
LOCUS       DAMKNB010000081        15764 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.086, whole genome shotgun sequence.
ACCESSION   DAMKNB010000081 DAMKNB010000000
VERSION     DAMKNB010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 15764)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15764)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15764
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.086"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            117..674
                     /locus_tag="PC494_002903"
     CDS             117..674
                     /locus_tag="PC494_002903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDF3913387.1"
                     /translation="MRVSREIVIQATSDIVNKDGLNKVSLKVIAEKLGIRTPSLYNHI
                     ESLDDLLLEVAHKGMREMNSQMIKAAIGNFGDTAIKCISIAYFNFIISNPGVYETIQW
                     ATWHGNNETLEIFDEYKSLLEKLILSCNLNTKNTGEVLNLIMSVLHGYSTLQLGKSLL
                     SKEEAIKGLVDSIDTVLLGIHKKYD"
     gene            768..887
                     /locus_tag="PC494_002904"
                     /pseudo
     CDS             768..887
                     /locus_tag="PC494_002904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008393964.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
     gene            complement(1024..1386)
                     /locus_tag="PC494_002905"
     CDS             complement(1024..1386)
                     /locus_tag="PC494_002905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004843367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF3913388.1"
                     /translation="MEIDYKAIGQRIKIARIKKGITQESVANIINMTPSHMSNVETGK
                     TKVSLPTLIAIANALSVSVDTLLCDNVLSSKVIFEKEAKDIFSDCDEYEIRSLVELLK
                     SAKTVIRKDREIRKQFEK"
     gene            complement(1820..2629)
                     /locus_tag="PC494_002906"
     CDS             complement(1820..2629)
                     /locus_tag="PC494_002906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HDF3913389.1"
                     /translation="MIKKLYKTSEFAELCGVKKHTLYHYDEIELLKPSITHENGYRYY
                     TIDQFEKFNIISVLKKAGTPLEEIKQYLNDLDTNTFLNVLHRKLMDLQEEVKKIEKMC
                     SMLRNVISTMEIHLNVNTEKIEIVNCEEEYLIATKIPEAVLTDEKTMLQGIGNHLQYC
                     LLHDYNFHVGEIVLEKNIKQGIFRESYYYSLIKNKVDDERLFIKPKGNYAVMYHQGSY
                     DSLYKTYQNMKNQLEEQGYHIVGNIYEEDLIDYLSEHNAENYIQKISMQVI"
     gene            2721..3344
                     /locus_tag="PC494_002907"
     CDS             2721..3344
                     /locus_tag="PC494_002907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidylate kinase-like family protein"
                     /protein_id="HDF3913390.1"
                     /translation="MKIITISREFGSGGRELGKQLADILNFDYYDKEIITAIARKKKI
                     DENYVSYILENHGWRNVPLTMCTSFTNILSMQSMKTDLLIEQSNVINQIASTGKDCVI
                     VGRNADILLKKYQPFNVFVCANMNFKIQRCIEKKLNNEHISKKELERKIREIDKNRAR
                     SREFFTSSLWGNQTSYHIIVNTSEWNIKHLSYAIANFSEYWFRRYEQ"
     gene            3341..4666
                     /locus_tag="PC494_002908"
     CDS             3341..4666
                     /locus_tag="PC494_002908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009295908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HDF3913391.1"
                     /translation="MIQLSDNFNYKRLLKFTFPTIIMLVISSIYGVVDGYFVSNFVGK
                     TAFTAVNFIMPFLLILGCVGFLFGTGGGALIAKTMGEGKKEEANEQFSLLIVTSAGCG
                     IILAVLGIVTMPWIASAMGADGQLLTDSILYGCVVIIAIPAYILQCEFQCLFATAEKP
                     KLGLYVAIMAGITNIVLDALFITVFKWGLVGAALATAIGQYVGGIIPLLYFSRQNNSL
                     LKFKKPKFDCDVLKKTVANGSSELMTNVSTSVVSMLYNAQLLKYAGEDGVASYGVLLY
                     VALLFQAVFIGYSVGTAPIISYHYGAKNYDELKNLRKRSLIVIICFAVFMFIIGEFLS
                     KPIAFIFVGYDNNLMEMTLRAFMIYSFSFLFSGFGVFGSSFFTALNDGLTSALIAFMR
                     ILVFQVVSVLIFPIFWGVNGIWFSIVGAEILATIMTAFFIIRKQKKYHY"
     gene            4687..5226
                     /locus_tag="PC494_002909"
     CDS             4687..5226
                     /locus_tag="PC494_002909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDF3913392.1"
                     /translation="MSLTIQKVTSYFKDLEKFEELNNEAFPDEERMSIQEMLNLVQSK
                     KIEVSALYDKQQFIGFYVLMIENHIGYILFLAISPEQRSKGYGGKALSLMKKQYPNCQ
                     IVLDMETIEDSAPNLQQRILRKQFYLQNGFYETEYLMEYKGLEMEVLCNQKTFQKNEF
                     ETLLKNLKIREIPFHLWKK"
     gene            5245..6636
                     /locus_tag="PC494_002910"
     CDS             5245..6636
                     /locus_tag="PC494_002910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="agmatine deiminase family protein"
                     /protein_id="HDF3913393.1"
                     /translation="MKRRLAGEWEPIKGVMLAWPPFLPHKYIVDLTQNYSVYMCVPNK
                     EEIEIAKYYLSKWGGNLKNLIFCIAPQGFDTPWVRDWGMHPIFDENGKLFLAGAEYKM
                     STPFVSINKPEIMFDCEHNLLTTNSYEQKEDQSQELIAKQIGLPFMKLPYALTGGNLM
                     SDGFNKLMSMHILQTENRAKGISDEEFFSMVARDTGMNEYYIFSNFANYGLQHIDCYL
                     KIIDEETLLVSRTPKEHYLYERYEKILEEVKKVESRYGRPFKIFRIDIVPFQKDSDEL
                     TAYVNSVILNSRVYVPMYGIEQDKIAIKQWQNALPGYEIKGYEFDFEKEPDIIKNRTG
                     YVRTGWGNEDVIHCRTRAIWDENMLYISVKRLEEIVSENDALEVTIQIVDYSKAGLDY
                     ENCRLFYRYYGFQTWESIRLEETTEAEIFFANMIGKSGDMIEYFVQAKSCSGMCETMP
                     PVAPKGTYKVTIK"
     gene            6651..7742
                     /gene="ytvI"
                     /locus_tag="PC494_002911"
     CDS             6651..7742
                     /gene="ytvI"
                     /locus_tag="PC494_002911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation integral membrane protein YtvI"
                     /protein_id="HDF3913394.1"
                     /translation="MNEQDHTSYQNKQRFLINFCYLVVILGLLMLLGKYAFSVLLPFV
                     FAFLIASLLNKPVLYISEKLLIKRGIVATISVFLFFLIAGIIVSVIGTYLIYGIKEIF
                     HFLPTMFEELVIPLTETVIKEVELFSGSFNFSFIELIEANMPVLMNEMSVFIVSLSNN
                     IVSGITDIVSSVPLLFMKTIITIVASIFIAIDYPTIKRFIVLQIPKNKSYLLAEAKAF
                     TIDTIIKCGFSYLLIFAITFSELYVGFVIINISYAGIIALFIALLDILPVLGTGSILI
                     PWCIISLFLGDYSMALGIALLYIVITIIRNIIEPKLVGKHMELHPVLALASMLTGLHF
                     FGFIGLFGIPLLIAFLKKLNDKEIIHILH"
     misc_binding    8045..8258
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            8512..9546
                     /locus_tag="PC494_002912"
     CDS             8512..9546
                     /locus_tag="PC494_002912"
                     /EC_number="1.2.1.38"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyl-gamma-glutamyl-phosphate reductase"
                     /protein_id="HDF3913395.1"
                     /translation="MNKIKVGIIGATGYVGAELIRLLMNHDKVEVTAIGSNSYVGKDI
                     VDIYPSIGYKNNMICIENEKVIDMCDVVFTALPHGVSEKFVIKAIKSKKKVIDLGADF
                     RIKDEEVYSKWYGVSFIDKILHKKAVYGLSEIYKEDIKDADIIANPGCYPTSISLPLM
                     PLLSSKLIKNNNIIIDSKSGLTGAGRELSISSHFTEVNENITAYKIGKHRHTPEIEQN
                     LSESCKEKVSVVFTPNLIPVNRGILSTIYCTKEDNISINDIHRKLTDYYEFKEFIEIL
                     PLDKVASLKNVRFSNKCVISLHENGDTLIICSAIDNMIKGSAGQAIQNMNIIFGIEEN
                     TGLKNIAPSF"
     gene            9587..10804
                     /gene="argJ"
                     /locus_tag="PC494_002913"
     CDS             9587..10804
                     /gene="argJ"
                     /locus_tag="PC494_002913"
                     /EC_number="2.3.1.1"
                     /EC_number="2.3.1.35"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional glutamate
                     N-acetyltransferase/amino-acid acetyltransferase ArgJ"
                     /protein_id="HDF3913396.1"
                     /translation="MEIIKGGVTVSEGFFASGIHCGLRKNKEKRDLALVYSDVLCDAA
                     AVVTQNKVKGNPVYVTQEHIKNGKAQAIIVNSANANTFNGKEGLINAYKMAKFTSDKL
                     NIKESDVLVASTGVIGKPLNIDLIEENMDELVNNLSKQGHIGAREAIMTTDIIKKEIA
                     VAIMYGDKKITIGGMAKGSGMIHPNMATTLGFITTDANIDGVLLKEALKIAVDKSFNR
                     VSVDGDTSTNDMVMILANGKAKNDRINKKDEHYQVFLSALTYVCIELAKLVAKDGEGC
                     TKLIECYINGALSEEHAVKLAKTVISSSLVKTAVFGADANWGRILCALGYAGEEIDME
                     KVDIIFESMKGYIEVCKNGNGLDFNEEKAKKILEDDEISILVDLNMGNARGNAWGCDL
                     SYDYVRINGSYRN"
     gene            10819..11679
                     /gene="argB"
                     /locus_tag="PC494_002914"
     CDS             10819..11679
                     /gene="argB"
                     /locus_tag="PC494_002914"
                     /EC_number="2.7.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetylglutamate kinase"
                     /protein_id="HDF3913397.1"
                     /translation="MINIEKANTLIEALPYIEKHQGKTIVVKYGGSAMKKDGLKESVM
                     EDLVLMSYVGINIVLVHGGGAEINKMLAKVDIESKFVNGLRYTDEETMEIVKMVLAGK
                     VNKDLVNKIHTKGGKAVGLCGIDNNMILCDPYKNYELGFVGEIKKVNVELIESCLKSG
                     YISVIATIGVGDDGETYNINGDTAASAIAKELNADKLILLTDVPGLLREPDEEKSLIT
                     EVILEDVDKLFEEGIITGGMIPKIEGCVDALNNGVNRVHILDGRVPHSIITELFTDSG
                     IGTLIRKENE"
     gene            11709..12896
                     /locus_tag="PC494_002915"
     CDS             11709..12896
                     /locus_tag="PC494_002915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate aminotransferase family protein"
                     /protein_id="HDF3913398.1"
                     /translation="MNNDNTISKWNEYFIDTYNQPNFVIDYGEGSCFFDTNGNKYIDF
                     TSGYGVSSLGYSNSNLKNALKEQVDKLLHTSNLYFNEPVLCSGEKIINSSGMAKVYFC
                     NSGTEANETAFKIARKYSSDKYGNGRGTIISLKDSFHGRTMMSLMATGMDKYHKYFYP
                     LPEGFKYIERNNIEDLKNNLDSTVCAIILEAIQGEGGVNVLEKDYVLEIVKICQEKDI
                     VVIFDEVQCGIGRTGKLFGYEYFDVKPDIVTVAKGLGAGIPVGGVLVNKKLSKVLGKG
                     DQGTTFGGNLLAMVAASVVLDEISKDGFYNEVLEKGNYIRKSIESFNNKVVLKTKGIG
                     LMIGIETNIESSIIEEKARKKGLLILTAGKNVLRFLPPLTISYKEIDEALEILKDILL
                     EIN"
     gene            13000..14022
                     /gene="argF"
                     /locus_tag="PC494_002916"
     CDS             13000..14022
                     /gene="argF"
                     /locus_tag="PC494_002916"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HDF3913399.1"
                     /translation="MNNISLKGKSFLTLKDFTKEEIRYLLTLSSYLKTKKKVGIKGDL
                     LQGKNIALLFEKTSTRTRCSFEVAAHDEGAHVTYLGPNDCHMGKKESVSDTAKVLGRF
                     YDGIEFRGFKQETVESLAKYSGVPVWNGLTDEYHPTQILADFLTVIENVDKDLNKVKF
                     VYVGDARNNMGNSLMIGCAKMGIHFVALAPKELWPNEELVKEMKEIAKKSKGDIMLTE
                     NIDDVKGADVIYTDVWVSMGEEEQYEARINQLKDYQVNMDMIKKTENENVIFLHCLPA
                     FHDLETKVAQEIYEKFGLSELEVTNEVFNSKYSKVFEEAENRMHTIKAVMVSTMTDVN
                     MNNNLV"
     gene            14149..14766
                     /locus_tag="PC494_002917"
     CDS             14149..14766
                     /locus_tag="PC494_002917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4878 domain-containing protein"
                     /protein_id="HDF3913400.1"
                     /translation="MKKIILALTTFLLAISLTACSSAKPEDTIESFFNSAKKFDFEGM
                     NKVMENNDEKYKDILKELDTKDPNAQYVLDYLKQNASKITYTIKDSEVKGDKATIKVE
                     CKFIDSTPLLQEIVAEAFTKMIGMSFSGQDLTDEKTTEMLVSIMKEKQKSVKETYVTK
                     NVEFECSKKDNKWIISSVNDAVADVLLSNLVTAGQEFSNSMNTLE"
     gene            complement(14986..15684)
                     /locus_tag="PC494_002918"
     CDS             complement(14986..15684)
                     /locus_tag="PC494_002918"
                     /EC_number="5.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid racemase"
                     /protein_id="HDF3913401.1"
                     /translation="MNEKLIGILAGMGPRSTAPFVDLIIDECQSQYGAKYDDEFPKMM
                     IYSLPTPFYIDRPINHELMKETIIDGLQKLESTGVNFIAMPCNSAHIYFKELKESINI
                     PILNIVEETVKKLPTISQKVTLFSTSSTFESTIYQNGIIHNGHEFIFKDEWQIKLNNL
                     IQNIKMDKENPHNIDIWNKLIEDVKNESIENIVIACTDLNVVLEKSYPSINIVDSSKC
                     LAESVVNKYLKLVK"
BASE COUNT         5880 a         1750 c         2786 g         5348 t
ORIGIN      
        1 aaactgtcaa gattttataa tagtataaag aattttataa attacaataa ttgacgaaac
       61 taattagatt agttaaacta ataaagtaat taattttaaa tgaaagaggg aaaatcatgc
      121 gtgttagtag agaaatagtt atacaagcta catcagatat agttaataaa gatgggctta
      181 acaaagtttc tttaaaagtt attgcagaaa agctaggaat acgtacacca tctttgtaca
      241 atcatataga aagtctagat gatttattac ttgaagtagc tcataaagga atgagagaga
      301 tgaatagtca aatgataaag gcggctattg gaaattttgg agatacagct ataaagtgta
      361 taagtatagc atactttaat tttataattt ctaatcctgg tgtttatgaa acaattcagt
      421 gggctacttg gcatggaaat aatgaaacat tagaaatctt tgatgaatat aaatccttat
      481 tagaaaaact tattctttct tgtaatctaa atacaaagaa tacaggtgaa gtattaaact
      541 taataatgag tgtacttcat ggttattcga ctttgcaact tgggaaatca cttttgagta
      601 aagaagaagc tataaaaggt ctagtcgatt ctattgatac tgtgttatta ggtattcata
      661 aaaaatatga ttaaggaggt aaataaatta ttttaactta tttattgaac acttcattac
      721 gtgggatgta aaataaaatt ttatcatttt tatgaaagga aaatagtata tttcaagaat
      781 atttactttc tgaattggta aaccctattt ttactgttgt cgttgataat gaaaaggtag
      841 ctgtaaaatt ccttgataat cagacaaaag cgacacaggt atcatagtat aaattgatat
      901 ttcataagga cagtaattgg aaaattattg gataggttat ttgattatat aaaaatgatt
      961 atataaaaaa agaaaagacc ttagctaaca acacatatca atttatacct tgaagctgtg
     1021 gttttatttt tcaaattgtt tgcggatttc tctgtcttta cggattacag tttttgctga
     1081 ttttagcagt tcaactaaag aacggatttc atattcatca caatctgaga aaatatcttt
     1141 ggcttccttt tcaaaaatta ctttggaaga aagtacatta tcacataaga gagtatcgac
     1201 tgatacagaa agtgcattgg caatcgcaat caaggttggc aggctgactt tcgtttttcc
     1261 tgtttccacg ttgctcatat gggatggtgt catgttgata atgtttgcaa cggattcttg
     1321 tgttatacct tttttaattc ttgcaatttt aattcgctgt ccgattgctt tataatcaat
     1381 ttccatagtt tttgttctcc tttcattctt ttaaatattg taactattta cagagcataa
     1441 tataatactc tatataaatg aataatttat ataatatata tttaagaaaa aaatttgcac
     1501 tacttttaag acaactacaa aagaaatgga ggcataaagc ctccatgtta agattttata
     1561 aaaagatagt aaaaaactga ttaaatggtt aacgaaaata aaaagctatt tctgtatctg
     1621 aaattcatga ggaaatgcag tttgcattga ggaaacaaat aatagcaatg aacctgaatt
     1681 tctacaaaaa tttggaaata acataccaac tttagaagat aaaaaaggac attttaagca
     1741 aattattata gacaatacga gatattaaaa aaggcgtgta tttctcatgt gatttgagat
     1801 atacacgctt tttatatttt caaataacct gcatagaaat tttttgaatg tagttttcgg
     1861 cgttatgttc tgataaataa tcaattaaat cttcttcata aatatttcca acaatatgat
     1921 acccttgttc ttctaactga tttttcatat tttgataagt tttatataaa ctgtcataac
     1981 tcccctggtg atacataact gcataatttc cctttggttt aataaaaagg cgttcatcat
     2041 ctactttatt tttaataagg ctataataat agctctctct aaaaattccc tgttttatat
     2101 ttttttcaag aacaatttct cctacatgaa aattataatc atgtaataaa caatattgta
     2161 agtgatttcc aataccttgt aacattgttt tttcatctgt tagtacagct tcaggaattt
     2221 tagttgcaat cagatattct tcctcacaat ttacaatttc gattttttct gtgtttacat
     2281 tgagatgtat ttccattgtt gaaatgacat ttctcaacat agaacacatt ttttcaatct
     2341 tcttcacttc ttcttgaaga tccattagct ttctgtgaag tacattaaga aaggtattgg
     2401 tatctaaatc attgagatat tgttttattt cttctaaagg tgtacctgct ttttttagca
     2461 cagaaataat attaaatttt tcaaattggt caattgtata ataccgatag ccattttcat
     2521 gggtaatact cggttttaat aattcaattt catcataatg gtaaagtgta tgttttttta
     2581 ccccacacaa ttctgcaaat tcacttgtct tatataattt tttaatcatt tttaaatctc
     2641 ctattgactt tagggttacc agatacttta ggataacata gaaagctttt atattcaatg
     2701 aaatgtgagg aaaagatatt atgaaaatta ttacaattag ccgagagttt ggaagtggtg
     2761 gacgagaact tggaaaacaa cttgctgata ttttaaattt tgactactac gataaagaaa
     2821 ttatcactgc tatagctaga aagaaaaaaa ttgacgaaaa ctatgtttcc tacatattag
     2881 aaaatcatgg ttggagaaac gttcctttaa caatgtgtac ttcttttact aatattttgt
     2941 ctatgcaatc catgaagaca gatttgttaa tagaacaatc aaatgttatc aatcagattg
     3001 ccagtacagg taaggattgt gttattgttg gtagaaatgc agatatatta ttaaagaagt
     3061 accagccatt taacgttttt gtttgtgcaa atatgaactt taaaatacaa cgctgtattg
     3121 aaaaaaagtt aaacaatgaa catatttcaa aaaaagaatt agaaagaaag ataagagaga
     3181 ttgataaaaa tcgagcaaga tcaagagaat tttttacgag ctccttatgg ggaaatcaaa
     3241 cttcctatca tattatagtt aatacatctg aatggaatat aaaacatctt tcttatgcaa
     3301 ttgctaactt ttcagagtat tggtttagga ggtatgaaca atgatacagt tgtcagataa
     3361 ttttaattat aaacgcttat taaaatttac atttcctaca attattatgc tggtaataag
     3421 ttctatttat ggggttgttg atggatattt tgtttcaaat tttgtaggga aaactgcttt
     3481 tactgctgtc aattttatta tgccattttt gctaatctta gggtgtgttg gctttctttt
     3541 tggaacaggt ggtggagctt taattgctaa aacaatgggt gaaggaaaaa aagaagaagc
     3601 aaacgaacag ttttcgttac tcattgttac ttctgctggt tgtggtatta ttctagctgt
     3661 tttaggtata gtaactatgc catggattgc ttctgctatg ggagcagatg gtcaattatt
     3721 gacagatagt attctttatg gatgtgtggt aattatcgct attcctgcct atattttgca
     3781 gtgcgaattt cagtgtttat ttgcaacagc agaaaagcca aaacttggat tatatgttgc
     3841 aattatggct ggaattacaa atattgtttt agacgcatta tttatcactg tttttaaatg
     3901 gggattggta ggtgcagcac tggcaactgc aatcggtcaa tatgttggtg gtatcattcc
     3961 attactttat tttagccgac aaaacaacag tttgcttaaa tttaagaaac ctaaatttga
     4021 ttgtgatgtt ttgaaaaaga ctgttgcaaa tggttcttca gaactaatga ctaatgtttc
     4081 cacatctgtt gtgagtatgc tgtataatgc tcaattacta aaatatgctg gcgaagatgg
     4141 cgttgcatcc tatggtgttc ttctttatgt agcgttacta tttcaagctg tttttattgg
     4201 gtattctgtt ggtactgccc ctataatcag ttatcattat ggagcaaaaa attatgacga
     4261 attaaaaaat ttaagaaaaa gaagtttgat tgtaattatt tgttttgctg tatttatgtt
     4321 tataataggc gaatttttat caaaaccgat tgcttttatt tttgtgggtt acgataataa
     4381 tttaatggaa atgacattaa gagcatttat gatttactct ttttcctttt tattttctgg
     4441 ttttggtgtt tttggttcta gtttctttac tgcattaaat gacggtttaa cttctgcgct
     4501 tattgctttt atgcgtattt tagtatttca agttgtatca gtacttatat tccctatatt
     4561 ctggggagta aatgggatat ggttttctat tgttggtgct gaaatattgg caactattat
     4621 gacggctttc tttataataa gaaaacagaa aaaatatcat tattaaatca atttggaggt
     4681 atctatatga gcttaacaat acaaaaagta acttcatatt ttaaagattt agaaaaattt
     4741 gaagaactta ataacgaggc atttccagat gaagaacgta tgtctataca agaaatgctt
     4801 aatttagttc aaagtaaaaa aatagaagta tctgctttat atgataagca acaatttatt
     4861 ggtttttatg ttttgatgat tgaaaatcat ataggatata tattatttct tgcaatttcc
     4921 ccagaacaac gctctaaagg atatggtgga aaagcactgt cacttatgaa aaaacaatat
     4981 cccaattgtc aaattgttct tgatatggaa actatagagg acagtgctcc taatttacag
     5041 caaagaattt taaggaagca attttatctt cagaatgggt tttatgaaac agaatatctc
     5101 atggagtata agggactaga aatggaagtt ttatgtaatc agaaaacctt tcaaaaaaat
     5161 gaatttgaaa cattgttgaa aaatcttaaa attagagaaa ttccatttca tttgtggaaa
     5221 aagtaagaaa gtgaggtatt agaaatgaaa agacgtttag ctggggaatg ggaaccgatt
     5281 aaaggtgtca tgcttgcatg gccacctttt cttccccata agtatattgt agatttaacg
     5341 caaaattatt ctgtatacat gtgtgtacca aataaagagg aaattgaaat tgcaaaatat
     5401 tatttaagta agtggggtgg aaatttaaaa aatttgattt tctgcattgc tccacaggga
     5461 tttgatacac catgggttcg tgattggggt atgcacccta tttttgatga aaacggaaaa
     5521 ctctttttgg ctggtgcaga atataagatg tcaacaccat ttgtatccat aaataaacca
     5581 gaaatcatgt ttgattgcga acataaccta ttaactacta actcttatga acaaaaagaa
     5641 gatcaatcac aagagttgat tgcgaaacag attggtttgc catttatgaa attaccttat
     5701 gcactaacag gcggaaatct tatgtcagat ggtttcaata aattgatgtc tatgcacatt
     5761 ttacagacag aaaatcgtgc gaaaggaatt tctgacgaag aatttttttc tatggtggca
     5821 agagatactg gaatgaatga gtattatata ttttctaatt ttgctaatta tggtttacaa
     5881 catattgact gttatttaaa aataattgat gaagaaacat tacttgtgag cagaacgcca
     5941 aaagaacact atttgtatga aagatatgaa aaaattttag aagaagtaaa aaaggtagaa
     6001 agcagatatg gacgtccatt caaaatcttt cgtatagata ttgttccgtt tcaaaaggac
     6061 agtgatgaac ttactgctta tgttaattct gtgattttaa atagtcgtgt ctatgttcca
     6121 atgtatggaa ttgaacagga taaaattgca ataaaacaat ggcagaacgc tttgcctgga
     6181 tatgaaatta aaggatatga gtttgatttt gaaaaagagc cagatattat aaaaaatcgt
     6241 acaggatatg tgagaactgg ctggggaaat gaagatgtta ttcattgcag gacaagagca
     6301 atttgggatg agaatatgct ctatatttcc gtgaaaagat tagaagaaat cgtttcagag
     6361 aatgatgctt tagaagttac tattcaaata gttgattata gtaaagctgg cttagattat
     6421 gaaaattgta gactgtttta tcgatactat ggttttcaaa catgggaaag tattaggtta
     6481 gaagaaacta cagaagcaga aatatttttt gccaatatga taggaaagtc aggtgatatg
     6541 attgaatatt ttgtgcaagc aaaaagttgt tctggaatgt gtgaaacaat gccccctgtt
     6601 gctccaaaag gcacatataa agttactata aagtaggagg tgcattttat ttgaatgaac
     6661 aagatcatac atcataccaa aataagcaga gatttttaat aaatttctgt tatttggtag
     6721 tgatattagg cttactaatg ttattaggga aatatgcgtt ttctgtatta cttccttttg
     6781 tttttgcatt tttaatagca agtttattga ataaaccagt cttatacata agtgaaaaat
     6841 tactaataaa gcgaggtatt gtagcaacca tatctgtttt tttattcttt ttaattgcag
     6901 gaataatagt aagtgtaata ggtacatatc taatatatgg aataaaggaa atttttcatt
     6961 tcctaccaac catgtttgag gaattggtaa tacctttgac tgaaacagtt ataaaagaag
     7021 tcgaactatt ttctggttca ttcaattttt cgtttattga attaatagaa gcaaatatgc
     7081 ctgtattgat gaatgaaatg agtgttttca tagtttctct ttcaaataat atcgtatctg
     7141 gtattactga tattgtttcg tctgttccat tactatttat gaaaacaatt attacaatcg
     7201 ttgcttctat ttttatagca attgattatc caacgataaa gagatttata gtgctacaga
     7261 tacctaaaaa taaaagttat cttttagcag aagcaaaagc gtttactatt gataccatta
     7321 ttaaatgtgg tttttcttat cttttaattt ttgctatcac tttttctgaa ttatatgtcg
     7381 gttttgttat tattaatatt tcttatgctg gaataattgc tttattcatt gctcttttag
     7441 atatactacc tgttttagga actggaagta ttctaatacc ttggtgtatt atcagtttat
     7501 ttttagggga ttattcaatg gcattaggaa ttgcactact atatattgtg attactatta
     7561 tcaggaatat tattgaacca aaattagttg gtaaacatat ggagttacat cctgtattgg
     7621 ccttagccag tatgctaaca ggattacatt tctttggatt tattgggttg ttcggtattc
     7681 cattgttaat tgcgtttttg aaaaagttaa atgacaaaga aatcatacat atattacatt
     7741 aggaaagaat agttgtatgt atgtctcttt tatggagaaa attgtgtttt ttctaaaaaa
     7801 cgctggatga aaaataattt tgacaaaggt atagcttttg aatgacttga ttcaagaggg
     7861 agaacttttt taaaatatat tacagcagga aattcatggt gtcctattac tgtagatatt
     7921 tataactcaa tttagataca aaatgctgga aattaattat atagaaaata tttccaaaaa
     7981 cttaaaaatt atattgacaa agttaaaaaa ataaactatc atataaaaca ataagaaaat
     8041 aaattgaaat cctgtgaaaa agagagtagc ataaagctag ttgatagaga gctgggaatg
     8101 gtggaagcct agtaacgaat tttattgtga atagagcttt ggaggagatt accagaagta
     8161 atagtatggt aattggtgaa tctcgcctta agagattaga gtgggtaaga ttatcttatc
     8221 aattagagtg gtaacgcggg tgtatattcg tctcttggtc tttgaccaag aggctttttt
     8281 aattttaaat gtacattttg tagatacttt ttaatttgag ttttaatgat tattgtaatt
     8341 ttaccaataa gagtggtacc gcggaaaatc gcctcttagt atttataatg ctaaggggtt
     8401 ttttgtttta attagagtat tttaatctac gtattatcaa atgattatca tatagtaaag
     8461 tggaaagata ggattttaag actatttgaa tataaaaatg gagggaacaa aatgaataaa
     8521 ataaaagttg gtattattgg tgcaactgga tatgtcgggg cagagttgat tagattatta
     8581 atgaatcatg ataaagtcga agtgacagcg ataggttcaa attcgtatgt tggaaaagat
     8641 atagttgata tatatccaag tataggatat aaaaataaca tgatatgtat agaaaatgaa
     8701 aaagttatag atatgtgtga tgttgtgttt acagcccttc cacatggagt tagtgaaaag
     8761 tttgtaataa aggcaattaa atcgaaaaag aaagttatag atttaggtgc tgactttaga
     8821 ataaaagatg aagaagtata tagtaaatgg tatggagtat cttttataga taaaatctta
     8881 cataaaaaag ctgtatatgg attaagtgaa atatacaaag aagatataaa agatgcagat
     8941 ataattgcaa atcctggatg ttatccaact agtatttctt taccattgat gccattacta
     9001 agttctaaat tgataaaaaa taataatata ataattgatt ctaaatcagg tcttacaggt
     9061 gctggtagag aattatcgat tagtagtcac tttacggagg ttaatgaaaa tatcactgca
     9121 tataaaatag ggaaacacag acatactcca gaaatagaac aaaatttaag tgaatcctgc
     9181 aaagaaaaag taagtgtagt ttttacacca aacttaatcc cagtaaatag gggaatctta
     9241 tcaactatat attgtacaaa agaagataat atttctataa atgatataca taggaaatta
     9301 actgattatt atgaatttaa agagtttata gaaattcttc cattagataa ggtagcttct
     9361 ttaaagaatg ttagattctc aaataaatgt gtaatatcat tacatgaaaa tggagataca
     9421 ttgataatct gttcagctat agataatatg attaagggat cagcaggtca agctatacaa
     9481 aacatgaata taatatttgg tattgaagaa aatacaggtt taaaaaatat tgcaccatca
     9541 ttttagaaat aaaaaatact aaactcatat aattaggagg ataaatatgg agattataaa
     9601 gggtggagtt acagtttcag aaggattttt tgcttcaggg attcactgtg gcttgagaaa
     9661 aaataaagaa aaaagagatt tagctttggt ttattcagat gttttatgtg atgcagcagc
     9721 agtagtaact caaaataaag taaagggcaa tcctgtttat gttacacagg aacacattaa
     9781 aaatggaaag gcacaagcta tcatagtaaa tagtgctaat gctaatacct ttaatggaaa
     9841 agaaggactt ataaatgctt ataaaatggc taaattcacc agtgataaat taaatattaa
     9901 agaaagtgat gttttggttg catctacagg tgttatagga aagccattaa atatagattt
     9961 aatagaagaa aatatggatg aattagtgaa taatctaagt aaacaaggtc atattggagc
    10021 aagagaagct attatgacaa ctgatattat aaaaaaagaa atagcagtag caataatgta
    10081 tggagataaa aaaataacta ttggaggtat ggcaaaaggt tctggcatga tacatcctaa
    10141 tatggcaaca acgttaggat ttataactac agatgcaaat attgatggag ttttgctaaa
    10201 agaagcttta aaaattgctg ttgacaaaag ttttaataga gttagtgtag atggagatac
    10261 aagtactaat gatatggtaa tgattctagc aaatggaaaa gcaaaaaatg atagaataaa
    10321 caaaaaagat gaacattatc aagtattttt gagtgcactt acatatgtct gtatagaact
    10381 tgctaaactt gttgcaaaag atggagaagg atgtacaaaa ctaattgaat gctatataaa
    10441 tggagcatta agtgaagaac atgcagtaaa attagcaaaa acagttatat cttcttcatt
    10501 agtaaagaca gctgtatttg gagctgacgc aaattggggt agaatactgt gtgctttagg
    10561 ttatgcaggt gaagaaatag atatggaaaa agttgatatt atttttgaga gtatgaaagg
    10621 atatattgaa gtatgtaaaa atggaaatgg attagatttt aatgaggaaa aagcaaaaaa
    10681 aatccttgaa gatgacgaaa taagtatatt agtagattta aatatgggca atgccagagg
    10741 aaatgcatgg ggatgtgatt taagctatga ttatgtaaga ataaatggaa gttatagaaa
    10801 ttaggaggat atactttaat gattaatata gaaaaagcaa atacacttat agaagcttta
    10861 ccatatatag aaaaacatca gggaaagact attgtagtta agtatggtgg aagtgcaatg
    10921 aaaaaagatg gtctaaaaga atctgttatg gaagaccttg tgttaatgag ttatgttgga
    10981 atcaatatag ttttagtaca tggtggaggg gcagaaatca ataagatgct agcaaaagtg
    11041 gatatagaaa gtaaatttgt aaatggtctt agatatacag atgaagagac catggaaatt
    11101 gtaaaaatgg tacttgctgg aaaggttaat aaagacctag taaataaaat acatacaaaa
    11161 ggtggaaaag cagtagggct ttgtggaata gataataata tgattttatg tgacccatat
    11221 aaaaattatg aacttggatt tgtaggagaa atcaaaaaag taaatgttga gcttatagaa
    11281 tcttgtctaa agtcaggtta tatttcagta attgcaacta taggtgttgg agatgatgga
    11341 gagacttata atataaatgg tgacacagca gcttctgcta tagctaaaga gttaaatgca
    11401 gataaattga tacttcttac agatgtccct ggtttgttaa gagagccaga tgaagaaaaa
    11461 tcattaataa cagaagttat attagaggat gttgataaat tatttgaaga aggtataatt
    11521 actggaggta tgatacctaa aatagaggga tgcgtagatg ccttaaataa cggagtaaat
    11581 agggtacata ttttggatgg aagagttcca cattctataa taacagagct atttactgat
    11641 agtggaatag gtacattaat aagaaaagaa aatgaataaa attataagtt taagagggga
    11701 gaataagaat gaataacgac aatacaattt caaaatggaa tgaatatttt atagatacat
    11761 ataaccaacc caattttgtc atagattatg gtgaaggaag ttgttttttt gatactaatg
    11821 gcaataaata catagatttt acaagtggat atggagtatc ttctcttggg tatagtaata
    11881 gtaatttaaa gaatgctcta aaagagcaag tagataaatt attacatact tcaaatttat
    11941 attttaatga gccagtgttg tgttcaggag agaaaataat taattcaagt ggaatggcta
    12001 aagtatattt ttgtaattct ggaacagaag caaatgaaac agcattcaaa atagcaagaa
    12061 agtatagtag tgacaaatat ggtaatggta gaggaactat cataagttta aaagactctt
    12121 ttcatggtag aacaatgatg tctttaatgg caactggtat ggacaaatac cataagtatt
    12181 tttatcctct tcccgaaggt tttaaatata tagaaagaaa taatattgaa gatttaaaaa
    12241 ataatcttga ttccacagtt tgtgcaataa ttcttgaagc gattcaaggc gaaggtggag
    12301 ttaatgttct tgaaaaagat tatgttttgg aaatagtaaa aatatgtcaa gaaaaggata
    12361 ttgtagtgat ttttgatgaa gtccaatgcg gtataggaag aactggtaaa ctttttggct
    12421 atgaatattt tgatgtaaaa ccagatatag ttaccgtagc aaaagggttg ggagcaggaa
    12481 taccagtagg aggagtattg gtaaataaaa aactttcaaa agtactagga aaaggagacc
    12541 aaggtacaac ttttggaggt aatttattag ctatggtggc agcttcagtt gtattagatg
    12601 agatatctaa agatggtttt tataatgaag tattagaaaa aggaaattat ataagaaaat
    12661 ctattgaaag ttttaataac aaagttgtat taaagacaaa aggtattggt ctaatgatag
    12721 gaattgaaac taatattgaa tctagtatta tagaagagaa agctagaaaa aaaggattgc
    12781 ttattttgac tgctggaaaa aatgtattga gatttttacc accattaaca atcagttata
    12841 aggaaataga tgaggctctt gaaatcctaa aagatatatt actagaaatt aactaaatat
    12901 tcaaaaaata gttaattaaa aaattagaag taaataaaaa agtaaagtgc taacaagttt
    12961 aattgaattt aaaaagttta taagaagggg cgaattaata tgaataatat aagtttaaaa
    13021 ggtaagagtt ttttgacatt aaaggatttt acaaaagaag agattagata tttattaact
    13081 ttatcaagtt atttaaaaac taagaaaaaa gttggtataa aaggcgattt gctacaagga
    13141 aaaaatatag ctttattatt tgagaaaaca tcaacaagaa ctagatgttc atttgaagta
    13201 gcagctcatg atgaaggagc acatgtaact tatctaggtc caaatgattg tcatatgggt
    13261 aaaaaagagt ctgtatcaga tacagcaaaa gttctaggaa gattctatga tggaatagaa
    13321 tttagaggct ttaaacaaga aacagttgaa agtctagcaa aatattctgg tgtacctgtt
    13381 tggaatggac ttacagatga atatcatcca acacaaatac tggcagattt tttaacagta
    13441 attgaaaatg tagataaaga tttgaataaa gttaaatttg tatatgttgg tgatgctaga
    13501 aataatatgg gaaactcact gatgatagga tgtgctaaaa tgggaataca tttcgtagca
    13561 ctagcaccta aggaactttg gccaaatgaa gaattggtta aggaaatgaa ggaaatagcc
    13621 aagaaatcca aaggagatat aatgttgact gaaaatattg atgatgttaa aggtgcagat
    13681 gttatatata cagatgtatg ggtttctatg ggagaagagg agcaatatga agcaagaata
    13741 aatcaactta aagattatca agtaaatatg gatatgataa agaaaactga aaatgaaaat
    13801 gttatatttt tacactgtct tccagcattt catgatttag aaactaaggt tgctcaggag
    13861 atttatgaaa agttcggatt atcagaatta gaggttacaa acgaggtatt taattcaaaa
    13921 tattcaaagg tatttgaaga agctgaaaat agaatgcata caataaaagc tgttatggtt
    13981 tctactatga ccgatgtaaa tatgaacaat aatttagtat agatatgttt taatatagac
    14041 tttactttaa tgaaaattta taaaatattt taaatatatt attcaaaaac tctcattata
    14101 tgttaaaata acttatgtat caacaaatta agagggagga tttgagatat gaaaaaaatc
    14161 atattagctt taacaacttt tttattagca atatctttaa cagcatgttc aagtgcaaaa
    14221 ccagaagata caattgagag tttttttaac agtgcgaaaa agtttgactt tgaaggcatg
    14281 aataaggtaa tggaaaataa tgacgaaaaa tataaggata tattaaagga attagataca
    14341 aaagacccaa atgcccaata tgttttagat tatctaaaac agaatgcatc taaaatcaca
    14401 tatacaataa aagacagcga ggttaaaggt gataaggcta caatcaaagt agaatgtaaa
    14461 tttatagatt caacaccatt acttcaagaa atagtagctg aggcatttac aaagatgatt
    14521 ggtatgagtt tttcaggaca agacttaact gatgagaaaa caactgaaat gttagtatca
    14581 attatgaaag aaaaacaaaa aagcgttaaa gagacttatg ttacaaaaaa tgtagagttt
    14641 gaatgttcta aaaaggataa taaatggata ataagttcag taaatgatgc agtagctgat
    14701 gtattgttat ctaatcttgt tacagcagga caagaatttt ctaactctat gaatacactt
    14761 gaataatatt gtttaggtgt agtaaagtaa taaatatatg attattttta taaataaaca
    14821 tataaatatt tatgaaggat accatttttg gtatcctttt tattaatata atgaaataca
    14881 tggttaattt ctatattgtc aagaaactat gatatatgtt ataagcctat actatttaag
    14941 ataaacttat aacatatatt ttttataata tagtgcatga aaaatttatt taactaattt
    15001 tagatattta ttgacaactg attcagccaa gcattttgat gaatcaacaa tatttattga
    15061 aggatatgat ttttctaaaa ctacatttaa atcagtacaa gcaattacta tattttctat
    15121 agattcattt ttaacatctt cgataagttt attccaaata tcaatattgt gtggattttc
    15181 tttatccatt tttatatttt gaataagatt gtttaatttt atttgccatt catctttaaa
    15241 tataaattca tgtccattat gtattatacc attctggtaa attgtagact caaaagttga
    15301 actagtcgaa aaaagagtta ctttttgtga gatagtaggt aattttttaa ctgtttcttc
    15361 tacaatattt aatattggta tattaataga ctcttttaat tctttaaagt atatatgtgc
    15421 tgaattgcat ggcattgcaa taaaatttac accagttgat tcaagctttt gtaatccatc
    15481 aattatagtt tctttcataa gttcatgatt tattggacgg tcaatataaa atggggtagg
    15541 taatgaatat atcatcatct ttggaaattc atcatcatat tttgctccat attgagattg
    15601 acactcatca ataattaaat caacaaaagg ggctgttgac cttggaccca ttccagccaa
    15661 aataccaatt aatttttcat tcataaaaat tatctccttt atatataaat atatttatgt
    15721 ataaaataaa aatctataaa agcataaaat tatattttat aata
//
LOCUS       DAMKNB010000082        15731 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.087, whole genome shotgun sequence.
ACCESSION   DAMKNB010000082 DAMKNB010000000
VERSION     DAMKNB010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 15731)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15731)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15731
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.087"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            complement(96..956)
                     /locus_tag="PC494_002919"
     CDS             complement(96..956)
                     /locus_tag="PC494_002919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-ADP-ribose hydrolase"
                     /protein_id="HDF3913402.1"
                     /translation="MAMKWRDYADDVNLFEDFDKTIKPLTDEQRRKNINTLIAYFSKE
                     VPSKIYNLSNDEIKPRDILRGLLNVYPPKEIAPEILNMLHNLLLIECEERELIDVNDI
                     EEVEEGIAIWRGNITNLRADAIVNAANNKLLGCLQPLHLCVDNEIHSCAGPRLREDCD
                     KIIKKQGHLEYTGDAKITRGYCLPAKFVVHTVGPIVSGGQPSKEQEKQLLHCYKSCLN
                     TIKEIDEIKNIVFCGISTGVFGYPKKEAANLAVSRVRLWLKENPEKNLKVVFNVFTEE
                     EEEKYRRIFK"
     gene            complement(1273..2601)
                     /locus_tag="PC494_002920"
     CDS             complement(1273..2601)
                     /locus_tag="PC494_002920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010963854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-alpha-glucosidase"
                     /protein_id="HDF3913403.1"
                     /translation="MEKFSVVIAGGGSTYTPEIILMLLDNLDRLPLRAIKLYDNDEER
                     QNKVAKACEILIKEKDPNIEYLATTCPKEAYTDVDFCLAHIRVGKLEMRELDEKIPLK
                     HGVVGQETCGPGGIAYGMRSIEGVLENIDYMEKYSPNCWMLNYSNPASIIAEAVRRLR
                     PNSRVINICDMPIGMEHNIARIAGLKSRKHMDIRYFGLNHFGWYTSIKDKKGNELLPK
                     LVEHIKEYGFINGEEGMKNDKKDSWFETNLFTKEIVKTDLTTIPSSYLKYYLFPDYVV
                     NHSDVNYTRANEVIDGREKEVFGSCALIEKQGHSKGSGLKIGIHAEFIVDLATALAFN
                     TQERMLLIVQNNGAIENIQDDAMVEIPCIVGKDGYEPLSIGKIPTFQKGLIEQQLAVE
                     KLVVDAWIEKSYNKLWQALMLSKTVPSATVAKELLDDLIEANKNYWPKLN"
     gene            complement(2749..3078)
                     /locus_tag="PC494_002921"
     CDS             complement(2749..3078)
                     /locus_tag="PC494_002921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HDF3913404.1"
                     /translation="MVPEMEEKVFSIISEAGDAKSDVMMSLKEIKKGDYNKAKHLLNS
                     ASEKIQTASKHHLELLSNAMNSEDSGTDFLVVHSEDHYSNALFAHSLVSELVDIFEMM
                     DPRINKN"
     gene            complement(3102..4391)
                     /locus_tag="PC494_002922"
     CDS             complement(3102..4391)
                     /locus_tag="PC494_002922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDF3913405.1"
                     /translation="MEALQNNLRRFLLPIAQKIEKQRHLQAIKEGMISITPIIIVGSL
                     SMLFMALNNMLPEGSAKTLLSENMDTLLIPNKFTMSLLSIYSAFFIAQALAKKYNLNH
                     VEIGMTAVVAQLVVCGQVVDGVLDTSYLDAQGLFVSILVALLVVDITKFMNDKNLVIR
                     FPKEVPSVVNKSFRNLTPMIVCIMLFTAIAAITKNVSGQPLPAIIMNFLAPAISSVDN
                     VFAVTIILFITQLLWFFGLHGAAITSSIWMPIAATYMAENATLIAAGGDPKYVFTIGF
                     YYGFLQVTGSGITLGLVYLMSRSKCKSFNSMGKVVILPSLFGINEPVIFGTPIVMNPY
                     MFVPFVFGPVLVGALNFMALKVGLVGLPIAEPPGFLPPGVAAFLMTLDWKAIVLVFAS
                     IILMTLIYYPFFKIMEKEELNKNAELATTLDDDSFDF"
     gene            complement(4407..4733)
                     /locus_tag="PC494_002923"
     CDS             complement(4407..4733)
                     /locus_tag="PC494_002923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDF3913406.1"
                     /translation="MNILLVCANGASTGVLVEKMKSFCSEHEKLKTKTINIEATSFEN
                     LKSYIEANDTDVVLVAPQIRFKEDDVVEACKNYKIAVGLIDTKHYGRMDAPSVMKSAI
                     ELYKNR"
     gene            complement(4868..5497)
                     /locus_tag="PC494_002924"
     CDS             complement(4868..5497)
                     /locus_tag="PC494_002924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3913407.1"
                     /translation="MQDKILRDKKANDPWARMTTRNGFSADEIISSFQKAIRRNMVEE
                     ACEFAYELYISSPELEDKLWRRILTISVEDIGMGDPSAVIIINNLNQVRKEYSYADGD
                     RPLFFIHAIRYLCACEKDRSSDLLKNIIIKGFAMGKVPEVMDVALDKHTYRGLEMGRD
                     SFHFLNEASIVIPEKEVDNDYKERYLKILEKYKQEEVIDTAFKFNHWQY"
     gene            complement(5712..8369)
                     /locus_tag="PC494_002925"
     CDS             complement(5712..8369)
                     /locus_tag="PC494_002925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDF3913408.1"
                     /translation="MIYKKDKVMKVLESSYRENEKGITANQLSEKTGIARNNISTYLN
                     QLFNEGMVTKIKGRPVYYIPANLNLNKNELLDTQSELLGIKKGTKVENKIKKDSFETL
                     IGKEHSLRPIIEKCKVAMLYPTNGLHTIIYGETGVGKSMIARYMYDYSIDSGIRKNKA
                     PFVTFNCADYANNAQLLMGHIFGVEQGAYTGAESSRKGLLEIANGGILFLDEIHRLPA
                     EGQEMLFTFIDKGTFKRLGDATKERESKVLIICATTENPTSTLLDTFNRRIPMKIEIP
                     SLRDRTMIERMELVKNFFKEESKSISISIKVHKEIIKSLLLYDCKNNVGQLQNDIKLA
                     VANGYLRYKRDNKEPVYIEKKYFDKSINEVSDDYREKSIKADEVITHGIEYFVFTSLG
                     EEEVINYNDINIINAVNTNLNKSVEMNIADASLFNNVKFKSMCESIRQIIKEDEEIDI
                     SESIFKSMAIYIKSVLDKSSSTNNIDLNQIRRNNRSEFKTALKIVGIIENEFDLFLSI
                     ETVAYITLFIVQAKQDEQNKIVNNINIIVAMHGETTASSMVKAVGDIIGKCSAISFDM
                     KLDKSYDEVIVDFKNLINNIDNKDVLLFTDMGSLNSFDEIIKKEKKCGVRVIPMVTTL
                     TVLEAVQKANMGLPLNDVYNSITNTRKYYFGTNEIQNKENLSKTIIIASHVSEGVDNK
                     TRKILEEKMSRYLDGIDIISVPYKTEKDLSLNITKLKESSNIVAVINEQRINIRGIDY
                     ISKKDIDKDENINKLKNIIKISIGYDDVVEGLKTSLKSSNYNRIFKGIKYVSDELFLV
                     FNIEKKYDKVIGLMMHLAFMVDGLIGNTREIEKLDKEKTLDYHKSLSKIKDIVSQLDK
                     KYNIEINEKECYQILLILEYAEIIEKDYQ"
     gene            complement(8728..9672)
                     /locus_tag="PC494_002926"
     CDS             complement(8728..9672)
                     /locus_tag="PC494_002926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009527644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF3913409.1"
                     /translation="MNREKILEIKNLKQYFHLDKSTTVKAVDDISFDIYKGEIFGLVG
                     ESGSGKSTTGKTIIRLHESTGGEVIYKGNCISDKKTYKFIKKDVNKSMQIIFQDSTSS
                     LNPRMTIADIISEPLKIQGICKNKTDRMNKVYEMLKLVGLDRSYANKYPSDFSGGQRQ
                     RIGIARALSVDPEFIIADEPIASLDVSIQAQIVNLFKKLQQEKNLTCLFIAHDLSMVR
                     HISDRIGVMYNGKLVELADSNELYNNPIHPYTKSLLSAIPVPDPRYAKSRNRIEYNSN
                     GYDCSNEKSLSWIEVSDGHFVYSSKSEINKYQQNLKVV"
     gene            complement(9665..10690)
                     /locus_tag="PC494_002927"
     CDS             complement(9665..10690)
                     /locus_tag="PC494_002927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF3913410.1"
                     /translation="MEHLLEVNNLSVSFKVEEGEVQAVRNVSFNLKKGETLAIVGESG
                     CGKSVLCKSLMRILPYNGYIKNGEVLLKSSDLVKKSEKEMEDIRGKNISMIFQDPMTS
                     LNPTISIGKQIAEAVIIHQGISKSEAKKRAIELIELVGIDNPEKRFKQFPHHFSGGMR
                     QRIVIAIALACNPDVLIADEPTTALDVTIQAQIIDLIKDLQHKIGLSIIFITHDLGVV
                     ATIADRIAVMYAGKIVEIGTVEDIFYDPRHPYTWGLLGSLPTLDSQDDYLYNIPGMPP
                     NLLNPPKGDAFAIRNKNALKIDYEKEPPMFKINDTHSAATWLLHPDAPEVDVPVRVNC
                     GRVISNE"
     gene            complement(10765..12333)
                     /locus_tag="PC494_002928"
     CDS             complement(10765..12333)
                     /locus_tag="PC494_002928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDF3913411.1"
                     /translation="MKLKKLKVLSLVMILSLMAGCSSGGDKDKKADTPKDGKVLVYGS
                     NDYTSINPALYEHGEINSLIFNGLTAHDENNKVVPCLAKDWKFDEATNTYTFNLRDDV
                     KWHDGEKFTANDVKFTIETIMNPDNASEIASNYEDITKIDVVNDNTIKITLKAPNTAM
                     LDYLTVGVLPKHALEGKDIATDEFNQKPIGTGPFKLEKWDKGQSITLVKNSDYFVKEP
                     GLDKVVFKIVPDDKAKAMQLKSGELDLAQITPKDMSNFEKDEKNFKVNIMKTADYRGI
                     LYNFNSKFFKDKKAKGLPNALSYAIDRKAIVDSVLLGHGVPAYSPLQMGPYNNPDIEK
                     FEYNPEKAKQEIEKLGWKLGSDGIYEKEGTKLAFEITAGESDQVRVDMAKICAQQLKE
                     IGVDAKAVVVTETDWANQDAHLIGWGSPFDPDDHTYKVFGTDKGANYSAYSNPTIDKI
                     LQKARETEDKDEKLKLYKQFQVEMTKDMPYTFIAYIDAIYVGKPNIKGLTPDTVLGHH
                     GVGIFWNIADWTIE"
     gene            complement(12446..13357)
                     /locus_tag="PC494_002929"
     CDS             complement(12446..13357)
                     /locus_tag="PC494_002929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF3913412.1"
                     /translation="MKPQYSDFEIVGENYILVAEDEHIETKKTLSKKIKELPYISIII
                     LSIIVIGSVFSSFIMTHEPTYMDLASSNLAPNKTFLFGTDSMGRDIYSMIWYGGKISL
                     FIGLFSTVISTVIGIVYGSISGSASELVDDAMMRFTEIILSIPSILIIIFVQAILGNS
                     NPVSMSIVIGITSWMNISKIVRTEVRQIKNSEYILAAKSMGGGFFYVLKQHLLPNFVA
                     SIMFMVVTNIGAAIGTESTLSFLGIGLPIEIVSWGSMLSLSEEALLSNRWWIILIPGI
                     FLVTTLVCITNIGNYIRKNNNKKSSNL"
     gene            complement(13341..14327)
                     /locus_tag="PC494_002930"
     CDS             complement(13341..14327)
                     /locus_tag="PC494_002930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF3913413.1"
                     /translation="MLKDILKKLLQFILVMFLLSFIVFYMARLAPGDPLISYYGDGVE
                     RMSTQEKENAMKKLGLDEPIYSQYIKWISNASKGEFGISFKYKQNVTSVINDVYINTI
                     ILGGSGYILTFVLALLLGIFCTLHEDKLIDRIICKLGTITNCIPSFWVALVLILIFSI
                     NLSILPSSGAYSMGEESSILSRISHLILPLTVLILSHLWYYTYMIRNKLLEEIREDYV
                     LLCKAKGLNNRTIVFKHCLRNIMPSYISIMAISIPHILGGTYVVEKVFSYPGLGTLCF
                     ESAKYHDYNMLLVLCLITGALVVFGNMLAQIINNKIDPRMKYDRGDTNEATI"
     gene            14687..15088
                     /locus_tag="PC494_002931"
     CDS             14687..15088
                     /locus_tag="PC494_002931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HDF3913414.1"
                     /translation="MLLKELYSKTMYTVEENFKENGLTHQQIIVIKLIAHNQELTISQ
                     LCDEMSLAKGTVSGIISRLEQIGYIEKFKKSNDKRNTYVKFTTTGFEFATNFKIKMQE
                     SFDDIFKNCDENELSDLVKNLRNILAKVKER"
     gene            15091..15489
                     /locus_tag="PC494_002932"
     CDS             15091..15489
                     /locus_tag="PC494_002932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03987 family protein"
                     /protein_id="HDF3913415.1"
                     /translation="MNYKLILAIVFITSALIFYTIGVFGERKAKILKKKHVIIFWLGF
                     IFDTLGTFTMSNIANSHTFEVKSALSQNLHSITGLLAIVLMLFHASWATFVLYKDDEE
                     KKKFFHKFSIVVWTIWLVPYFIGMFIGMAG"
BASE COUNT         4953 a         2737 c         1736 g         6305 t
ORIGIN      
        1 ttatatttta ttaattttta ctacttgtaa attattatct tatacaatga atttgtatta
       61 tataataagt atttttagga ttctgttaca taatattatt taaatattct tctatatttc
      121 tcttcttctt cttcagtaaa cacattaaat acaactttta aatttttttc aggattttct
      181 tttagccata gtctaactct acttacagca agattagctg cctctttttt tggataacca
      241 aatacacctg tagaaattcc acaaaaaaca atatttttta tttcatcaat ttcttttatt
      301 gtatttaaac atgatttata acaatgaagc agttgctttt cttgctcttt acttggctga
      361 ccaccagata caataggtcc aacagtatgt actacaaatt ttgcaggtaa acaataacct
      421 ctagttatct tagcatctcc agtatattct aaatgccctt gtttttttat tattttgtca
      481 caatcttctc taagtctagg acctgcgcat gaatgtatct cattatccac gcatagatgt
      541 aatggttgta aacaccctaa taacttgtta tttgcagcat ttactattgc atctgctctt
      601 aaattcgtta tattacctct ccatatggca atcccttcct ctacttcttc tatatcattt
      661 acatctatta actctctttc ttcacattca atcaacaata aattatgtaa catattaagt
      721 atctctggag caatttcttt tggtggatat acattcaaaa gtcctctaag tatatctcta
      781 ggcttaattt catcatttga taaattgtat attttagaag gaacttcttt tgaaaaatat
      841 gcaattaaag tgtttatatt ttttcttctt tgttcgtcag ttagaggctt gatagtttta
      901 tcaaaatcct caaataaatt tacatcatca gcataatctc tccacttcat agccatctct
      961 ccattcttgt attttagact taaaaataat tatgtattta tgtacatatt tatttatttc
     1021 tataaacacc tacataaatc ctgttaaaag tgtaaatttt ttattatgca acttctctgg
     1081 ttatttctat tgattgatag taaattattg tatctaaatt taatccaact aacaagtaac
     1141 taaacctact ttcctaactg caaaatacac tatgttttcc acttgtatct catttgtaga
     1201 taaataaagt ccctacaaat acattaacta agctatgtac taaactgtag gaactttaaa
     1261 aatatattat tcttaattaa gttttggcca ataattttta tttgcttcta ttaaatcatc
     1321 tagtaattct tttgcaactg ttgcactagg aactgtctta gatagcataa gtgcttgcca
     1381 caatttatta taagacttct caatccaagc atcaactact aatttttcaa ctgctaattg
     1441 ttgttctatt aaaccttttt ggaatgttgg tattttccct attgataatg gttcataccc
     1501 gtcttttcca actatacatg gaatttcaac catagcatca tcttgtatat tttctatagc
     1561 tccattattt tgaactatca ataacatacg ctcctgtgta ttaaaagcta gagctgtagc
     1621 taaatccact ataaactctg catgtattcc tatcttaagc ccactgccct tagaatgtcc
     1681 ttgcttttct atcaatgcac atgaaccaaa aacttctttt tctcttccat caataacttc
     1741 attggcacga gtataattta catcagaatg atttacaaca taatctggaa atagatagta
     1801 ctttaagtaa ctacttggta ttgtagttaa atctgttttt actatttctt tagtaaataa
     1861 attagtttca aaccaactat ctttcttgtc atttttcatt ccttcttcac catttataaa
     1921 accatattct tttatatgtt ctactaattt tggtaaaagt tcatttcctt ttttatcttt
     1981 aattgaagta taccaaccaa agtgatttaa tccaaagtat cttatatcca tatgtttacg
     2041 agatttgagt cctgcaatcc ttgctatatt atgttccata cctattggca tatcacaaat
     2101 atttattacc ctagaattag gtctcaatct tctaacagct tccgctatta ttgatgctgg
     2161 attagaataa tttaacatcc aacaatttgg agaatacttt tccatataat ctatgttttc
     2221 aagaacacct tctatagacc tcattccata agctattcca cctggtccac aagtttcttg
     2281 accaactact ccatgtttta gaggtatctt ttcatctagt tctctcattt caagttttcc
     2341 aactcttata tgagctaaac aaaaatctac atctgtataa gcctctttag ggcatgttgt
     2401 tgctaaatac tctatattag ggtccttttc ctttattagt atttcacaag ctttagctac
     2461 cttattttgt ctttcttcat cattatcata taatttgatt gctcttaatg gtaacctatc
     2521 taagttatct agcaacatta atatgatttc tggggtatat gtacttcctc ctccagctat
     2581 tactactgaa aatttttcca taataatatc tccttttcta tttaaaaatt tactgtattt
     2641 ataaataaat ttataaatac tagtacttta aagtaaaagg gagttcattt attaaatcta
     2701 ttgatttaat aaactatagc caaacttcaa gcactattta caagaaattt aattcttatt
     2761 aattcttggg tccatcatct caaatatatc tacaagttca gatactaaag aatgagcaaa
     2821 taatgcattt gaataatggt cttcagagtg cacaactaaa aaatcagtcc cactatcttc
     2881 actattcata gcatttgata gtaattctaa atgatgcttt gatgctgttt gtattttctc
     2941 tgaggctgaa tttaaaaggt gttttgcttt attgtagtca ccttttttta tttccttaag
     3001 agacatcatt acatcacttt tagcatctcc tgcttctgat attatactaa atactttttc
     3061 ttccatttca ggtaccatat ccttctcctt ctaatgactt gttaaaaatc aaagctatca
     3121 tcatctaatg ttgtagctaa ttctgcattt ttatttaatt cttccttctc cattatctta
     3181 aagaatggat aatatatcaa ggtcataagt attatacttg caaatactaa tacgattgcc
     3241 ttccaatcta atgtcatcaa aaatgctgca acccctggag gtaaaaagcc tggtggttct
     3301 gcaataggta atcctactaa tcctactttt aatgccataa aattaagtgc tccaaccaat
     3361 acaggtccaa atacaaatgg tacaaacata tatgggttca taactattgg tgttccaaat
     3421 attactggct catttattcc aaatagtgat ggtaaaatca caacttttcc catactatta
     3481 aaactcttac acttacttct tgacataagg tacactaatc ccaaagttat ccctgaacca
     3541 gttacttgca agaaaccata gtaaaatcct attgtaaaca catattttgg gtctcctcct
     3601 gctgctatca gtgttgcatt ttctgccata tatgtagctg ctattggcat ccatatactt
     3661 gaagttattg ctgctccatg aagcccaaag aaccataata attgagttat aaatagtatt
     3721 atagttactg caaaaacatt atctacactg cttatagctg gtgctaagaa attcattata
     3781 atagctggta gtggttgacc tgagacattt ttagttattg ctgctattgc tgtaaataac
     3841 attatacata ctatcattgg agttaagttt ctaaaacttt tatttactac actaggtact
     3901 tcttttggaa atctaattac gagattttta tcattcataa acttagtaat atcaactact
     3961 aaaagtgcta ctaatatact tacaaataaa ccttgtgcat ctaaataact tgtatctaat
     4021 acaccatcta ctacttgtcc acatacaaca agttgtgcaa caactgctgt catacctatt
     4081 tctacatgat taagattata ttttttagct agtgcctgag ctataaaaaa tgctgaatat
     4141 atagataata aactcatagt aaatttatta gggataagta atgtatccat attttcagat
     4201 aataatgttt ttgcacttcc ttcaggtaac atattgttta atgccataaa taacatactt
     4261 aaagaaccaa caattattat tggggtaatg cttatcatac cttcttttat agcttgaaga
     4321 tgcctttgtt tttcaatctt ttgtgctatt ggaagaagaa atcttcttaa attattttga
     4381 agtgcttcca tttttattcc ccccaattat ctatttttat ataattcgat tgccgacttc
     4441 ataacagaag gagcatccat acgaccataa tgcttagtat ctattaaacc aactgctatt
     4501 ttgtaattct tacaagcttc aactacatca tcttccttaa acctaatttg tggtgctaca
     4561 agtactacat ctgtatcatt agcttcaatg tatgatttta aattttcaaa tgatgttgcc
     4621 tctatattta tagttttagt ttttaacttt tcatgctcac tacaaaaact tttcatcttt
     4681 tccacaagta cacctgttga agctccattt gcacatacta ataaaatatt cataattacc
     4741 ctcctacaat atctaacctc ttttgttttc taatttttta tcagccaatt cttactctaa
     4801 ttcctatcag tttttacttt aattcttatt attttatttt aattcttatt aatatttact
     4861 ctaattctta gtactgccaa tgattaaact tgaaagccgt atctataact tcttcttgct
     4921 tatatttttc taatattttt aagtatcttt ctttataatc attatctact tctttttctg
     4981 gtattactat actagcttca tttaaaaagt ggaatgaatc ccttcccatt tctaatcctc
     5041 tatatgtatg cttgtcaagt gccacgtcca taacttctgg aactttaccc attgcaaatc
     5101 cttttataat tatatttttt aataaatcac ttgatctatc tttctcacat gcacaaagat
     5161 atcttattgc atgtatgaaa aataaaggtc tgtctccatc tgcatatgaa tattcctttc
     5221 ttacttgatt taaattattt atgattatta cagctgatgg gtcccccatt cctatatctt
     5281 caactgatat tgtaagtatc cttctccata gcttatcttc taattctggt gatgatatat
     5341 atagttcata agcaaattca caagcttctt ccaccatatt tcttcttata gctttttgaa
     5401 atgacgatat tatttcgtct gcactaaatc cgtttcttgt agtcattctt gcccatgggt
     5461 catttgcctt tttatctctt aatattttat cttgcatatt atttactcct ttttatttaa
     5521 attttaatta tttatattgc tcatttaata atataagcaa gtattatgcc agttttttta
     5581 gacactttaa aacactgtta tttcaatcat ttttatcatc aaaacttaga tactttgtct
     5641 aagtatattt atatgtgtct aatattaata ttattttaga ctaaaaaaaa ttaccaaata
     5701 agtttttata ctcattggta atctttttcg attatttctg catattctaa tattaataat
     5761 atttgatagc actctttttc attaatttct atattatatt ttttatctaa ttgagatact
     5821 atatctttta ttttgcttag actcttgtga taatcaagtg ttttttcttt atcaagcttt
     5881 tcaatttctc tagtatttcc aatcaaccca tctaccatga aagctaaatg catcataagt
     5941 ccaattactt tatcgtattt cttttctata ttaaatacta aaaacaattc atcagacaca
     6001 tattttatac ctttaaatat cctattataa ttagagcttt ttaaggatgt ctttaaacct
     6061 tcaactacat catcataacc tatacttatc tttataatat tttttaattt attgatattt
     6121 tcatccttat ctatatcttt tttgctaata tagtcaattc ctctaatatt aattctttgt
     6181 tcattgatta ctgcaacaat attactactt tctttaagtt tcgtaatatt taaacttaaa
     6241 tctttttctg ttttatatgg gacagatata atatctattc catctaagta cctactcatc
     6301 ttttcttcta atatttttct tgttttatta tctacacctt ctgaaacatg tgatgctata
     6361 ataattgttt tagacagatt ttctttattt tgaatttcat tagttccaaa atagtacttt
     6421 ctcgtgttag ttatagagtt gtatacgtca tttaaaggta atcccatatt ggccttctga
     6481 actgcttcta acacagttaa tgtcgtcacc ataggaatta ctcttactcc acactttttt
     6541 tctttcttta taatttcatc aaaagagttt aatgaaccca tatctgtaaa tagtaataca
     6601 tctttattgt ctatattatt aattaaattt ttaaaatcta caattacttc atcatagctt
     6661 ttatctaact tcatatcgaa agaaatagca ctgcactttc caataatatc accaactgct
     6721 tttaccatac tacttgctgt agtttctcca tgcatagcaa ctataatatt aatgttattc
     6781 actattttat tttgttcatc ttgtttagct tgtactatga ataatgtaat atatgctaca
     6841 gtttctatag ataaaaataa atcaaattca ttttcaatta ttccaactat ttttaatgct
     6901 gttttaaatt cacttctgtt atttcttcta atttgattca aatctatgtt gtttgtagag
     6961 ctacttttat ccaatacgct ttttatataa attgccattg acttaaatat tgattcactt
     7021 atgtctattt cttcatcttc tttaataatt tgtcttattg attcacacat gcttttaaac
     7081 ttaacattat taaatagaga agcatctgct atattcattt ctacagattt attaagatta
     7141 gtatttactg cattaataat atttatatca ttgtagttaa taacttcttc ttctcctaat
     7201 gacgtaaata caaaatattc tattccatgt gttataactt catctgcttt aatagacttc
     7261 tctctataat catcactcac ttcatttata gatttatcaa aatatttttt ctctatataa
     7321 actggttctt tattatctct tttatatctt agatatccat ttgcaacagc taattttata
     7381 tcattttgaa gttgacctac attattttta caatcataaa gtaatagtga tttaattatt
     7441 tctttatgta cttttattga aatagaaata ctttttgatt cttccttgaa aaaatttttg
     7501 actaattcca ttctttcaat cattgtccta tctctcaatg atggtatttc tattttcatt
     7561 ggtattcttc tattgaatgt atctaatagt gttgatgtcg gattttctgt agtagcacat
     7621 attattaata ccttagactc tctttctttc gttgcatctc ctagtctttt aaatgttccc
     7681 ttatctataa aagtaaacaa catttcttga ccttctgctg gtagtctatg aatttcatct
     7741 aaaaatagta tccctccatt tgcaatttcc aaaagacctt ttctggaaga ttctgcacct
     7801 gtataagctc cttgttctac cccaaaaata tgtcccataa gtaattgtgc attattagca
     7861 taatcagcac aattaaatgt tacaaaagga gctttatttt ttctaattcc actatctata
     7921 gaataatcgt acatatatct agcaatcata ctctttccta ctcctgtttc tccatagata
     7981 atagtatgaa gtccatttgt aggatagagc attgcgacct tgcatttttc tattataggt
     8041 cttaaactat gttctttacc tattagtgtt tcaaaactat ctttttttat tttgttttct
     8101 acttttgttc ctttttttat gccaagcaac tcactttgtg tatcaagcaa ttcattcttg
     8161 ttaaggttaa gatttgcagg gatataatac acaggtcttc cttttatctt cgtaaccata
     8221 ccctcattga ataattggtt taaatatgta cttatattgt ttcttgcaat tcctgtcttt
     8281 tctgataatt ggttagctgt aatccctttt tcattttccc tatatgatga ttctaaaact
     8341 ttcattactt tatctttttt atatatcatt acaagctccc ctacattata gtattttatt
     8401 aactaaaacc cctatacaca ctttattttt taataaactc ttattcttta actaaggtta
     8461 taatttatca aattttcctt actttaaatt atagaaaatt attgtagaaa aaataagatt
     8521 attgctcatt ttttctacat tactattttt aattttatag tactttctta acaacatact
     8581 ttacttgttt ttaattttat tatatttgaa tttattatat ttgaaaagta gaaataaaaa
     8641 accctatttt ggagtagttt taaaatttct ccaaaaatag ggttttagtt tgtatttcaa
     8701 ataaatacct gttcaagtat ttttatacta aacaactttt aaattttgtt gatatttatt
     8761 tatttctgat ttagaagaat atacaaaatg tccatctgaa acctcaatcc aacttaatga
     8821 cttttcattt gaacaatcat atccattaga attatactct attctatttc ttgacttagc
     8881 atatctaggg tcaggaacag gaattgcaga aagtagtgat tttgtatatg gatgaatagg
     8941 attattatac aattcatttg aatctgccaa ttctactaat tttccattat acataactcc
     9001 tatacggtca ctaatatgtc tcaccataga taaatcatga gctataaata aacaagttaa
     9061 attcttttct tgttgcaatt ttttaaataa atttactatt tgtgcttgta tagacacatc
     9121 caaagaagct ataggctcat cagctattat aaattctggg tctactgaaa gagctcgtgc
     9181 tatgccaata cgctgtcttt gtccacctga aaaatcagat ggatacttat ttgcataact
     9241 tctatcaagt cctactagct ttagcatctc atatacttta ttcattctat ctgttttatt
     9301 tttacagata ccttgaattt ttagtggctc tgaaattata tctgcaattg tcatacgtgg
     9361 atttaatgat gaagtagaat cttgaaaaat aatctgcata cttttgttta catctttttt
     9421 tataaatttg tacgtttttt tatctgatat gcaatttcct ttgtaaatta cttctccacc
     9481 agtagattca tgtagtctta ttatagtttt accagttgta gattttcctg aacccgactc
     9541 tcctaccaat ccaaatatct cacccttata tatatcaaaa cttatatcat caactgcttt
     9601 tacagtagta cttttgtcca aatgaaaata ttgctttaag ttttttattt ccagtatttt
     9661 ttctctattc attagaaatc acccttccac aatttactct aactggtaca tctacttcag
     9721 gtgcatctgg gtgcaataac caagttgctg cactatgtgt atcattaatt ttaaacattg
     9781 gtggctcttt ttcataatct atcttaagtg catttttatt ccttattgca aaagcatctc
     9841 cttttggtgg gttcaataaa tttggaggca ttccaggtat attatataaa tagtcatcct
     9901 gcgaatctaa agtaggtaat gaacccaaca acccccaagt atatggatgt ctagggtcat
     9961 aaaatatatc ctctacagtt cctatttcta caatctttcc tgcatacata actgctattc
    10021 tatcagctat agttgcaact actcctaaat catgagttat aaatattatt gacaaaccta
    10081 ttttatgttg taaatccttt attaaatcaa ttatttgagc ttgtatagtt acatctaaag
    10141 cagttgtagg ttcatcagca atcaatacat ctggattaca ggcaagtgct atagctatta
    10201 ctatacgttg tctcattcca cctgaaaaat gatgtggaaa ttgtttaaat cttttctcag
    10261 gattatcaat tccaaccaat tcaataagct ctatggctct cttttttgct tcacttttac
    10321 ttataccttg atgaatgatt acagcttctg caatttgctt tcctattgat atagttggat
    10381 tgagagatgt catagggtct tgaaatatca ttgatatatt ctttcctctt atatcttcca
    10441 tctctttttc agacttctta accaaatcac ttgatttaag taaaacctct ccatttttaa
    10501 tatatccatt gtatgggagt atcctcatca aactcttaca cagtacagat ttcccacaac
    10561 cagattctcc aactatagcc aatgtctcac ctttttttag attaaaagat acatttctta
    10621 cagcctgaac ttctccttct tctactttaa aacttacaga tagattatta acctccaata
    10681 aatgttccaa aaaccatcaa cccctatgct attcaaacct tagggatata tttttatccc
    10741 taaggtttct aattaatttc agtattattc aattgtccag tcagctatgt tccagaatat
    10801 acctacacca tgatgaccta aaactgtatc aggtgttaat ccttttatgt ttggttttcc
    10861 aacatatatt gcatctatat aagcaataaa tgtataaggc atatccttag tcatttctac
    10921 ttggaattgt ttatataact ttaatttttc atctttatct tctgtttctc ttgctttttg
    10981 aagtatttta tctatagtag gattagagta agcactgtaa tttgcacctt tatctgttcc
    11041 aaatacttta tatgtatggt catctgggtc aaatggactt ccccaaccta ttaaatgagc
    11101 atcttgatta gcccaatctg tttcagttac aacaacagct ttagcatcaa caccaatttc
    11161 ttttaactgt tgtgcacata ttttagccat atcaactcta acttggtcac tctcacctgc
    11221 tgttatctcg aaagctaact tagtaccttc tttttcatag attccatcag aacctaattt
    11281 ccaacctagc ttttcaattt cttgtttagc tttttctgga ttatattcaa acttttctat
    11341 atcaggatta ttatatggtc ccatttgtaa aggtgaatat gctggtacac catgtcctaa
    11401 taatacactg tcaactattg cttttctatc tattgcatag cttaaagcat ttggtaatcc
    11461 tttagctttt ttatctttaa agaatttaga attaaaattg tataatatac ctctatagtc
    11521 ggctgttttc attatattta ctttaaaatt cttttcgtct ttttcaaagt tagacatatc
    11581 tttaggagtt atttgagcta ggtctaattc tcctgatttt aattgcattg ccttagcctt
    11641 atcatctgga acaatcttaa agactacttt atctaatcct ggttctttta caaaataatc
    11701 actattctta acaagtgtta tactttgacc tttgtcccat ttttcaagtt taaatggtcc
    11761 agtacctatt ggtttttgat taaattcatc agtagctata tccttacctt ccaaagcatg
    11821 ttttggtaat actcctactg ttaaataatc aagcattgct gtatttggag cttttaaagt
    11881 aatttttata gtattatcat taaccacatc aatttttgtt atatcttcat aatttgatgc
    11941 tatctcagaa gcattatctg gattcattat agtttctatt gtaaacttaa catcatttgc
    12001 tgtaaatttc tctccatcat gccacttaac atcatctctt aaattaaaag tatatgtatt
    12061 tgttgcctca tcaaatttcc agtcctttgc tagacaagga accaccttat tattttcatc
    12121 atgagctgtt aatccattaa atattaacga atttatttct ccatgttcgt atagtgcagg
    12181 atttatactt gtatagtcat tacttccata aacaagcacc tttccatctt taggcgtatc
    12241 tgccttctta tctttgtctc ctccactaga acaacctgcc attagactaa gtatcattac
    12301 taaacttaaa acttttaact tctttaattt catgatgctc ccccttttgc tttttataaa
    12361 atatttttca aagctttgac cccatttatt taaatagata tttcaaatac ctcagtattt
    12421 gcttatttaa tactcaaatg ctgatttata aattactaga ttttttatta ttattctttc
    12481 ttatataatt acctatattt gttatacaca ccaatgtggt aaccaaaaat atacccggaa
    12541 tcagtataat ccaccatcta tttgaaagta atgcttcctc tgacaaagat aacatacttc
    12601 cccaagaaac aatttctatt ggtaaaccaa ttcctaaaaa gctaagtgtc gattcagtac
    12661 caatagctgc gcctatgttt gttacaacca tgaacattat tgatgccaca aaatttggaa
    12721 gtaaatgttg ctttaataca tagaagaatc ctcctcccat gctcttagct gctagtatgt
    12781 attcgctatt ttttatttgt ctaacttctg ttctcactat cttagatata ttcatccaac
    12841 ttgttatccc tattactatg gacatagata ctggatttga atttccaagt atagcttgta
    12901 caaatattat aattaatatt gaaggtatac taagtatgat ttctgtaaac ctcatcattg
    12961 catcatctac aagttcagat gctgaaccac ttatactacc ataaacaatt cctataacag
    13021 ttgatattac agtggaaaat agtcctataa ataaagatat ttttcctcca taccatatca
    13081 tagaatatat atctctaccc attgagtctg ttccaaataa aaaagtttta tttggagcta
    13141 aattagaact tgctaaatcc atgtatgttg gttcatgtgt cattataaaa gatgagaata
    13201 cacttccaat gactatgatt gataaaataa taattgatat atatggtaat tctttaattt
    13261 ttttagataa ggttttcttt gtttctatat gttcatcttc tgctactaaa atataatttt
    13321 ctcctacaat ttcaaaatca ctatattgtg gcttcattag tatcacctct atcatatttc
    13381 attctagggt ctattttatt gtttataatt tgagctaaca tattcccaaa tactactaaa
    13441 gcccctgtta ttaagcataa aactaataac atattataat catgatactt tgcactttca
    13501 aagcaaagtg ttcctaaccc aggataagaa aaaacttttt caactacata agttcctcct
    13561 agtatatgag gtatcgaaat ggccataata ctaatatatg atggcattat atttctcagg
    13621 caatgcttaa aaacaatagt tctattattt aaaccttttg ctttacataa aagcacataa
    13681 tcttctctta tttcctctag taatttattt cttatcatat atgtgtaata ccatagatgg
    13741 cttaatataa gtactgtaag aggtaagatt agatgtgata tcctacttaa tatactggac
    13801 tcttctccca ttgaataagc accactactt ggaagtatac ttaagtttat actaaatata
    13861 agtatgagta ctaaggcaac ccaaaatgat ggaatacagt tggttattgt tcctaatttg
    13921 catatgattc tatcaatgag cttatcttca tgtaatgtac aaaatattcc taacaataag
    13981 gctagcacaa aggtaagtat atatcctgaa ccacctaata ttatagtgtt tatatagaca
    14041 tcatttataa cagaagtaac attttgttta tatttaaatg aaattccaaa ttcccctttt
    14101 gatgcatttg aaatccattt tatatattga ctgtatattg gttcatccaa accaagtttt
    14161 ttcatagcat tttctttttc ttgtgtactc attctttcta ctccatcccc atagtaagag
    14221 attaatgggt ctcctggagc aagtcttgcc atgtaaaaaa caataaaaga taataaaaac
    14281 attactaaaa taaactgcaa caactttttc agtatatcct ttaacaaacc ccaacccccc
    14341 tttgttgcaa taaaaaaaac cacataaaag caaacgtaaa gtaacgttaa aaccttcgtg
    14401 gttccattat cattaaacaa aattaaattt tctatattta tctatgagtt aattttagca
    14461 tcatttatta actgtgtaaa caaacttttt aaaaattgtt aaaatttcat caaattattt
    14521 tatttatacc taaaataaaa tttttatatt ctattcttca ttattttcta taaaattata
    14581 aaattttagg ttgactatat aagaaaagta tattatatta gtttgtatgc aaaccattta
    14641 agaggtgatt ttattgaaaa gtaattatga ctgttttaga atagccatgc tcttaaaaga
    14701 actttattct aaaactatgt acacagtaga agaaaatttt aaagaaaatg gattaacaca
    14761 ccaacagatt atagttataa aactgatagc tcataatcaa gaacttacaa tatcacaact
    14821 atgtgatgaa atgtctttag ctaaaggtac ggtttcaggc ataatcagca gattagaaca
    14881 gattggatat atagaaaaat tcaagaaatc taatgataaa agaaatacat acgttaagtt
    14941 tacaacaaca ggatttgaat ttgccacaaa ttttaaaatt aaaatgcaag aaagttttga
    15001 tgatattttt aaaaattgtg atgaaaacga attgagtgac ttagtaaaaa atcttagaaa
    15061 tatattggca aaagtaaagg agagataatt atgaattata aattaatact tgcaatagta
    15121 tttataacat cagctttaat tttctacact ataggtgtat ttggagaaag aaaggcaaaa
    15181 attttaaaaa agaaacatgt aattatattt tggcttggtt ttatatttga tactttagga
    15241 acatttacaa tgagtaacat agccaacagc catacttttg aagtaaaatc tgctttatca
    15301 caaaaccttc atagtattac aggtcttctt gcaattgtgc ttatgctttt tcatgcaagt
    15361 tgggctactt ttgtcctata caaagatgat gaggaaaaga aaaaattctt tcataagttt
    15421 agtatagttg tatggactat atggttagtt ccatatttta taggtatgtt tattggtatg
    15481 gctggatagt aaaataaaaa gtgtgaaaga aggatgtagg taaatttgta taagacaaat
    15541 ttacctacat ccttctttca cacttttaca tatttattta taatactcca ttatttcttt
    15601 catgttcctt aatacctata tagaatattt aattgtttct atagtatttt attattttct
    15661 cacacttttt catatatata ttgttttact atttcttcat atgtatatat gaaatattcc
    15721 attatttcta t
//
LOCUS       DAMKNB010000083        15532 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.088, whole genome shotgun sequence.
ACCESSION   DAMKNB010000083 DAMKNB010000000
VERSION     DAMKNB010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 15532)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15532)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15532
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.088"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            93..1484
                     /locus_tag="PC494_002933"
     CDS             93..1484
                     /locus_tag="PC494_002933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide MFS transporter"
                     /protein_id="HDF3913416.1"
                     /translation="MSSTESVSKKSGHPKSFWLICMTILWERFSYYGLTALLVLFFTA
                     SVAQGGLGLSTQEATSMFGLFTGLIYLTPLVGGWLADKVLGQQKCISIGALLIAIGDF
                     VLFASSTSIAMVWVGLSIIILGNGFFKSSCSNIVGDIYPKTDVSRKDAAYSLFYMAVN
                     VGAFIAPIICGLLSDNVFAVRGASGDIVSYGYKMAFLICGIGMMLGMIIFTLLAPKLL
                     NEVGKYPVTKGNKGEKIEYGPLTKLEKNRIIAMVILFLFVVLFWTAYYQTQSSFMIYV
                     RDNVNRTLFGFEMPVAWLTSLNAILCVALCPVLATLWVKLSHTKRGDFSIPVKMGLGM
                     IIMGVGFIVMVFATLANGPDGMVKASILFIVLTYIFTTVGELFLSPIGLAMFNKLAPA
                     KYATLSMGAWYLTSFFASLLSGKIAGFTATLGFLQIFGGIATVLIIFGLILLGIRNVL
                     TRLMAMDLLTKEK"
     gene            1737..3530
                     /locus_tag="PC494_002934"
     CDS             1737..3530
                     /locus_tag="PC494_002934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HDF3913417.1"
                     /translation="MNIKDRLSGLRKFMEEKNIDAYMIPSSDNHQSEYVGDYFKSREF
                     ISGFNGSAGTVIVTKDEAGLWTDGRYFIQAESQLEGSTIKLFKMGQEGCPTTDEYLYK
                     NIPEGGTLGFDGRVISAREGATLAEKLSKKGIKIEYQYDLIDGIWPDRPALSDSKAFL
                     LDVKYCGESFSSKLARLREKMSEKGTSTHVITTLDDIAWLFNIRGGDVKYNPVVLSYA
                     VITLKEVYLFVDESKLNEEILNELAKENVQIKPYNDVYEFVKNIDKTEKVLLDGTKLS
                     YTIYNNIPCEVEKVDEFNPVMFFKAQKNEVELENIRNSHVKDGVAFTKFMYWLKKNVG
                     KMEITEISATQKLEDLRREQEGFFEPSFNTIAAYKEHAAMMHYSATPESNYKLEAEGL
                     FLVDSGGQYYDGTTDITRTTVLGPISDELKLHFTSVARGMINLSKAKFLHGCRGYNLD
                     ILSRSCMWNMGIDYQCGTGHGIGFVLNVHEAPNGFRWRVVPERFDSAVLEEGMVTTNE
                     PGIYIEGSHGIRTENEIVVRKAEKNFYGQFMEFEVVTLAPIDLDGIVPELMNKDEKDY
                     LNWYHKLVYDKISPFLTDEEREWLKVYTRAI"
     gene            complement(3611..4993)
                     /locus_tag="PC494_002935"
     CDS             complement(3611..4993)
                     /locus_tag="PC494_002935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide MFS transporter"
                     /protein_id="HDF3913418.1"
                     /translation="MSVLKTQEKLKQPRDLYFCCSIFTFVGLAYYGMKLVLLLFLAEQ
                     VSKGGLGLTPAESASMLASFLAWTYFSPVIGGWVSDRFLGPKNCIILGMLMVSIGYFL
                     GYIANSKMDINIMIFLSGLGIGFYKGNLHTMVGNLYTNDDPRKDGAFSITYMATNLGT
                     LFGPLICGLVANEWFAMKSGLSISMYGYRYVFLFSSITVLIGLFFFIFGNRKFYKPLN
                     NDPINGRESIRKSLEYKKMLASRPLTLIEKKRIIVILVLAFFTVFFWIAYNQASMSIA
                     LYTKEHINLTVGNFQIPTSWIDSYNGLLCVILGPISALVWVKLSQTKKGDLSVPKKMS
                     LGFILLAIAFLFMIVAVIQTGTDPNSIHKASVFWVVGFLTFQSIGEICFSPVGYGMVN
                     KLSPEKYISFLMGVWFLGKFAANKLSGYTQAIIDQLGMLQVFIVIPSFLLIFGIILLI
                     MNKKLVELSN"
     gene            5251..5598
                     /locus_tag="PC494_002936"
     CDS             5251..5598
                     /locus_tag="PC494_002936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HDF3913419.1"
                     /translation="MIRKKSELQVEVKENLNGGIGKVKLENIIQNEELKGKGRLFKRV
                     ALPVGSSIGVHDHTTDFEVYYILKGKGKVFDNGEFVEVNEGDVVYTADGEKHSIENIG
                     EEDLEFVALVLYM"
     gene            5616..6650
                     /locus_tag="PC494_002937"
     CDS             5616..6650
                     /locus_tag="PC494_002937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3913420.1"
                     /translation="MTGKIEEIKDKINRFCNSNLNQEYKDISFKILQNLLDNNKEIIH
                     SSRADIWSSAILNIVLEQNLLYNKKHPLHITKKEFSKQIGVSLNTINNKSSLIKDVCS
                     IDFLNQDTIAISNVEFWVKETNSKSKSVDLDLEKKKILYKRYIKLSQDANSDIESIRY
                     MEEAVNIGKSMITKEDKELGFWKGLSTRAYMIALESLARKLESINNLKESKKVLEYLI
                     EINPSDEQGIRYKLLNVLIRLNDRTSINKLFELYKEEKSATWMYSKALYYFKNKSMFL
                     ANDSIKVARSKNKYVGLYLLDWRNAFGREFVTEEEKAEAVYYYDENIVIWNEVKGSMD
                     WLLKKMLEFS"
     gene            complement(6699..7748)
                     /locus_tag="PC494_002938"
     CDS             complement(6699..7748)
                     /locus_tag="PC494_002938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDF3913421.1"
                     /translation="MEINYKKRNFKSFAKRKNIEISVQRYLIDALSYMALGLFSSLLI
                     GTIFNTLGDNFNISLFTEVISPLAKQVTGPAIAVAIAYGLQAPPLVLFSCALVGACGN
                     ELGGPVGAFVATLFAVEVGKLVSKETKIDILVTPAVTILIGVLVAELIGPAVSAFMTS
                     FGNIIMQATTMQPIIMGALVSALVGIALTLPISSAAICMMLSLGGLAGGAATVGCCCQ
                     MVGFAVMSFRENGVGGLVAQGLGTSMLQVPNIIKNWKIWIPPTVASILLGPLSTTIFK
                     MENIPIGSGMGTCGLVGQFGTVTAMQSAGKGGISMWVGILLLNFILPAIVTLLISEFM
                     RKKGLIKPEDLKLDV"
     gene            8023..9558
                     /locus_tag="PC494_002939"
     CDS             8023..9558
                     /locus_tag="PC494_002939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3913422.1"
                     /translation="MIFVKNKKYRKIAIIISIPILLVAQYYLFKFGILRPMVKGVEIE
                     IVDGEYVKDIDKYVVKLNETVTLSTGEYIKVPSYAKNPNIWFNVLDNSGTLKIDGNKM
                     TALKVGYSSVGIMKNSRVLKKATIKVVDPEVESLDMEINGDLKHVGDSATIESTIEVD
                     YDKFKKSYKPVYKSSNENILKIKGNKVSAVGVGKATIYAKCGNKEIERTFRIQARVAE
                     INMDDIKIEVDQNEKLKPDIITSPPGLEPPKIYYELVDSKLPVERAISLSSNGNVVGL
                     REGKDRVRITCGDKSKVITVTVVKETITNDYIQNLVGSHKIVNNKVIIKLEWDYMKDV
                     FDYDIYLKDKLSGESFKKIKSITINESDLGKSNKVYATIEVDMKGNQNIDFDIYVIGK
                     KDSDTTKPSNVINITNGNGNSNNDNNIKDMRVENISANVDRDNNVIRVNWSSISHKDC
                     TYSIYVKNNTNGDGEFTLYQSDIQGNEHTISIPEGDLNLDIYVVANYNGNSSQNSDVI
                     NVR"
     gene            complement(9743..10429)
                     /locus_tag="PC494_002940"
     CDS             complement(9743..10429)
                     /locus_tag="PC494_002940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate/glutamate racemase family protein"
                     /protein_id="HDF3913423.1"
                     /translation="MKTIGLIGGMSWESTITYYQVINTVIKERLGGLHSSKCILYSVD
                     FQEIEECQSSGNWEKSAKILADAAIKLQEAGADFIVICTNTMHKVSDKIQESIHIPLL
                     HIADVTATVLREKEIKKVALLGTKYTMEQDFYKNVIINNGIEVLIPNEEDRIIVNDTI
                     FNELCLGIISESSKKAFLSIIDKLGKQGAEAVILGCTEIGLLIKQNDTSIPLFDTTVI
                     HAIEAALSSI"
     gene            10554..11936
                     /locus_tag="PC494_002941"
     CDS             10554..11936
                     /locus_tag="PC494_002941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HDF3913424.1"
                     /translation="MPINSFENYPMTWKPKLDNRKPPIYKTLAMLLEEDIKRGNLNPG
                     DKLPPQRELADFLDLNLSTITRAFKLCEEKGLICAKVGKGTFISSDVNVSNTLLYQTE
                     SKDIIELGTVHPPYEQNTYIIDFIKNVLKQPEMDRFLQYMSPSGTYMQKKSIAKWIER
                     NNVYTSEENILLSTGGQNAICATLLGLFKAGDRIATDSLSFSGIKSIAKMIGIQLVPI
                     PQENNEISIEYLESYCKNENIKGIYLIPDYHNPTTHTMSDLSRKKIAKIAKQYNIIII
                     EDAINSIFRDGIQTPIFSLASDNTIYIFSTSKFLCAGLRVAFVVAPKRYIENLENALY
                     NMNLMVSPFTAEIVHRLLYSPIIDKIIEEKRDAIIERNEVADKVLSDYNLIGDKNCSF
                     RWLLLPDELDGKSFEISAKNLGVQVYCAERFSVGNSTVPKAVRICVTAPKDVEELEKG
                     LNIIKSLLKS"
     gene            12338..13606
                     /gene="eam"
                     /locus_tag="PC494_002942"
     CDS             12338..13606
                     /gene="eam"
                     /locus_tag="PC494_002942"
                     /EC_number="5.4.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 2,3-aminomutase"
                     /protein_id="HDF3913425.1"
                     /translation="MNEQTRISLERAAELKSKIDDYIQARKTINRGLEKEEEINKRKQ
                     KILSILNGTEEDWNNYKWQLSNRITDVDTLSKIITLTKKEKEYIKEVGTQFRWAISPY
                     YLSLIDPEDICDPIKLLSIPTHIELEDEQEDLDPMGEEYTNPAGCITRRYPDRLIINV
                     TNECAMYCRHCQRRRNIGQQDSHKSKAIIQESIDYIRENEEIRDVLVTGGDALTLKDD
                     YLEWILSQLKEIPHVDYVRLGTRTLVTMPQRITDEFCNMLKKYHPIYINTHFNHPMEI
                     TKESKEACEKLANAGVPLGNQAVLLNGINNDKFVMRCLNQELLKIRVKPYYIFQSKHV
                     KGTKHFNTSVDDGLEIMEYLRGYTSGMAIPTYIVNAPKGGGKTPLLPQYLVSKGTDYV
                     MLRTWEGKVIKMEDEPAVDIKKLIKEQAQD"
     gene            complement(13699..14055)
                     /locus_tag="PC494_002943"
     CDS             complement(13699..14055)
                     /locus_tag="PC494_002943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3913426.1"
                     /translation="MKKALISLLVLSCLLLTAPVNESSYADSQKNVPVSQNTKLTQEQ
                     AKELLVKYNNEVDYIYQGNASDFEALKAKNLNGYVFLPDADGDIGYFVNENTSEIYYF
                     HPSGYLELVNQQQNNK"
     gene            complement(14206..15300)
                     /locus_tag="PC494_002944"
     CDS             complement(14206..15300)
                     /locus_tag="PC494_002944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HDF3913427.1"
                     /translation="MQDKKIYLNIVLTVVVSYILIKVIDNYKYFFGVISLLMSLLTPF
                     IIAFVLAYIFNPLVKFLESKLNFKRIYSLLLTYGVLIVILISFILFTVPSIVNSLADL
                     VAQIPTYIDKTEQFLFDLGKSLQSVDPNTLKEYGDKIMSVMPKFSNLLIGSLGGIFST
                     TFSVGKFIVQFLLGFIICFYILLEKEKFLLFTKKVVYISLGKKYGDFIIELCQSLNLN
                     IGKYFTGKILDSFIVGVLSGIGLYFLKSEYALLFGTLMGVMNMVPYFGPVIGMAPVVI
                     INLFSNPTIALTSLIYLIIIQQVEVTFIEPKIVGGQLGLSPFFTILAVTVGGGFFGIP
                     GMILSAPVMGVIKIYFCEFVNRRHDKIQME"
BASE COUNT         6009 a         1920 c         2501 g         5102 t
ORIGIN      
        1 catagaaaag atgatattat aagtatgtgc taaaatggtt aaagcaatat taatattaaa
       61 tttaactata aaacaaaagg gggcgttttt ttatgtcaag tacagaaagc gtatctaaaa
      121 aaagtggtca tccgaagagt ttttggctta tttgcatgac aattttgtgg gaaagattta
      181 gttattatgg tttaacagct ttattggtat tattttttac agcaagtgta gctcaaggtg
      241 gtttaggtct ttctactcaa gaagcaacat ctatgtttgg cttatttaca ggtcttatat
      301 atcttacacc attagtcggt ggctggttag cagataaagt tttaggtcaa caaaaatgta
      361 tttctatagg tgcactttta atagcaatag gagatttcgt actatttgct tcatctacat
      421 ctattgcaat ggtttgggta ggtctatcaa taattatttt aggaaatggt ttttttaaat
      481 caagttgctc aaatatagtt ggggatatat atcctaaaac tgatgtgtca agaaaagatg
      541 cagcatacag tttattctat atggcagtaa atgtaggagc atttatagct ccaataatat
      601 gtggattgct ttctgataat gtatttgcag taagaggagc aagtggagat atagtatctt
      661 atggatataa gatggcattt ttaatttgtg gtataggcat gatgttaggt atgattatat
      721 ttacacttct tgcaccaaaa ttattaaatg aagtcggaaa atatcctgtg actaaaggta
      781 ataaaggtga aaaaattgag tatggaccac ttactaagtt ggagaaaaat aggataatag
      841 caatggttat tttattttta tttgtggtct tattctggac agcatactat caaacacaaa
      901 gttcttttat gatttatgta agggataatg taaatagaac tctatttgga tttgaaatgc
      961 cagtagcatg gcttacatca ctaaatgcta tattatgtgt ggctttatgc ccagtattag
     1021 ctaccctatg ggttaaatta tctcatacca aaagaggtga tttctctatt ccagttaaaa
     1081 tgggattagg aatgataata atgggtgttg ggtttatagt tatggtattt gctacattag
     1141 ctaatggtcc agatggaatg gtaaaggcta gtatattgtt tatagtattg acttatatat
     1201 ttacaacagt aggtgaatta ttcttatctc ctataggact tgcaatgttc aataaattag
     1261 ctccagctaa gtatgctacg ttgtctatgg gagcctggta tctaacaagt ttttttgcaa
     1321 gtttattatc aggaaagatt gctggtttta cagccacact tggtttttta cagatatttg
     1381 gaggaatagc aacagtttta ataatatttg gtttaatatt attgggaata agaaatgtat
     1441 taacaagatt aatggctatg gatttactaa caaaagaaaa ataattcatg acgaattatt
     1501 gtaaataaat gaattacttt aaataaagga agttacattt aaatataaaa ttaaatgtaa
     1561 tttcctcttt gattatgaaa aaaagcttta cacaaataga tattataatt aaaattataa
     1621 ttgtgataat tagagtgtat aagatttata taaattatac aaaaaatatt tatgtaataa
     1681 actttacata cttatatatt tagttattca aactattatt tcgaggaggt cttgttgtga
     1741 atataaaaga tagattaagt ggattaagaa aatttatgga agaaaaaaat atagatgcct
     1801 atatgattcc atcttctgat aatcaccaaa gtgaatatgt aggagattac ttcaaatcaa
     1861 gagaatttat atcagggttt aatggttcag cagggacggt tattgtgact aaagacgaag
     1921 ctgggttatg gacagatgga agatatttta tacaggcaga atctcaatta gaaggaagta
     1981 caataaaatt attcaaaatg ggacaagaag gttgcccaac tacagatgaa tatttatata
     2041 aaaatattcc tgaaggagga actttaggat ttgatggtag agttatatct gctagagaag
     2101 gagctacatt agctgaaaaa ttatctaaaa aaggtataaa gatagaatat cagtatgatt
     2161 taatagatgg tatatggcca gatagacctg ctttatcaga tagtaaagca tttttattag
     2221 atgttaaata ttgtggagaa agttttagct caaaattagc tagattaaga gaaaaaatga
     2281 gtgaaaaagg tacttctact catgtaataa ctactcttga tgatatagca tggttattca
     2341 atataagagg tggagatgtt aaatataatc cagttgtact ttcttatgca gtaataactt
     2401 taaaagaagt ttatctattt gttgatgaaa gtaagttaaa tgaagaaata ctaaatgaac
     2461 tagctaagga aaatgttcaa ataaagccat ataatgatgt gtatgaattt gtaaaaaata
     2521 tagacaaaac tgaaaaagtt ttattagatg gaactaagct tagttataca atttacaata
     2581 atataccttg tgaagttgag aaagttgatg agttcaatcc agtaatgttt tttaaagctc
     2641 aaaaaaatga ggtagaatta gaaaatataa gaaattcaca tgtaaaagat ggtgtagctt
     2701 tcactaaatt tatgtactgg ttaaagaaaa atgtaggtaa gatggaaatc actgaaataa
     2761 gtgctactca aaaattagag gacttaagaa gagagcaaga aggtttcttt gagccaagtt
     2821 tcaatacaat tgctgcatat aaagagcatg ctgcaatgat gcactatagt gcaactccag
     2881 agtcaaatta taaattagag gcagaaggat tatttttagt agattcaggt ggacaatatt
     2941 atgatggaac tactgatata actaggacta cagttttagg acctataagt gatgaattaa
     3001 aactacactt tacttctgta gcaagaggaa tgataaatct ttctaaggct aagttcttgc
     3061 atggttgtag aggatataac ttagacatac tatctagaag ttgcatgtgg aatatgggaa
     3121 ttgattatca atgtggaact ggacatggta taggatttgt gctaaatgtt cacgaagctc
     3181 caaatggatt tagatggaga gtagtacctg aaagatttga tagtgcagtt cttgaagaag
     3241 gaatggtaac tactaatgaa ccaggtatat atatagaagg ttctcatggt ataagaacag
     3301 agaatgaaat tgtagttaga aaagctgaaa agaatttcta tggtcaattt atggaatttg
     3361 aagttgttac gttagctcct attgacttag atggtatagt accagaatta atgaataagg
     3421 atgaaaaaga ttatttaaac tggtatcata agttagttta tgataaaata tcacctttct
     3481 taactgatga agaaagagaa tggttaaaag tttacactag agctatatag tttgtactag
     3541 atacaataaa aatcgaggta ttataatgcc tcgatttttt attgtatatt ttattaactt
     3601 taaaaaattt ttaatttgat aattctacta attttttatt cattataagt agtataattc
     3661 caaatatcaa taaaaatgat ggtatcacta tgaagacttg taacatacca agttggtcta
     3721 taatagcttg cgtatagcca gataatttat ttgctgcaaa tttgcctaaa aaccaaacac
     3781 ccattaggaa tgaaatatac ttttcaggcg aaagtttatt taccatacca tacccgactg
     3841 gagaaaagca aatttctcct atactttgga atgttaaaaa tccaactacc caaaatacac
     3901 ttgctttgtg aattgaatta gggtctgttc ctgtttgtat aactgctact atcataaaca
     3961 aaaatgctat ggctaatagt ataaaaccta agctcatttt ttttggcaca cttaaatcgc
     4021 cttttttagt ttgagataat tttacccata ctaaagcaga gataggtcca agaataacac
     4081 aaaggagacc attgtatgaa tctatccatg aagtaggaat ttgaaaattg ccaacagtaa
     4141 gatttatgtg ttcctttgta tagagtgcaa tagacataga ggcttggtta tatgctatcc
     4201 aaaaaaatac tgtgaaaaaa gctaacacca atattactat tattcttttt ttctcaatca
     4261 aagttaaagg tcttgaagcg agcattttct tatattctag tgattttctt atagactctc
     4321 tcccgttaat agggtcatta ttcaaaggtt tataaaactt tctgtttcca aatataaaga
     4381 agaataaacc tattagaacc gtaattgatg aaaataaaaa tacatatcta tatccataca
     4441 tacttataga taatccgctt ttcatagcaa accattcatt agcaactaaa ccgcatatta
     4501 aagggccaaa taaagtacct agattagtag ccatatacgt aatagagaaa gctccatctt
     4561 ttcttgggtc atcattggta tataagtttc caaccatagt atgtaagttt cctttataaa
     4621 aacctattcc taatccagat aaaaatatca tgatgtttat atccatctta ctatttgcta
     4681 tgtatcctag aaaataacca attgaaacca ttagcattcc aagtataata cagtttttgg
     4741 gacctaaaaa tctatcactg acccatccac caataactgg agagaaataa gtccatgcta
     4801 aaaaagatgc aagcattgat gcggattctg ctggtgttaa ccctaaacca cctttggaga
     4861 cttgttcagc taaaaacaat aataatacca atttcatacc atagtatgca agtcctacaa
     4921 aggtaaatat tgaacagcag aaatataaat ctctaggttg tttaagtttt tcttgcgttt
     4981 ttaaaactga catatgtcga gaacctccag ataaatagtt taacaaaatt ttaccatact
     5041 atatgagtat atgttttttt catatagacg tcaacttgta agataattta attaagtcga
     5101 aatatatgta aaaatagtat catttttgtg tattcagtaa tattttttta tgataatata
     5161 tgttattatt atattaaaat acaaacatat ttatggaaag gatatgccaa tttagtagtt
     5221 agattgattg tttggcaggt gggatgagct atgataagaa agaaatctga attacaagta
     5281 gaagtaaaag aaaatttaaa tggtggtata ggaaaggtta agcttgaaaa cataatacaa
     5341 aatgaagagc ttaaaggaaa aggaagacta tttaaaagag tagctttacc agtaggaagt
     5401 tcaattggtg tgcatgacca tacaacagat tttgaagtat attatatact aaagggaaaa
     5461 ggtaaagtat ttgataatgg ggaatttgta gaagtaaatg agggtgatgt agtgtataca
     5521 gctgatggcg aaaaacattc tatagaaaat ataggagaag aagatcttga gtttgtagca
     5581 ctagttttat atatgtaaaa tatggaggag gagtcatgac aggcaagata gaagaaatta
     5641 aggacaagat aaatagattt tgcaactcca atttaaatca agaatacaaa gatataagct
     5701 ttaaaatttt gcaaaacctt ttagataata ataaagagat aattcattct tctagagctg
     5761 atatatggtc ttcagctata ctaaatatag ttttagaaca aaatctttta tacaataaga
     5821 agcatccact acatataaca aaaaaagagt tttcaaaaca aataggtgtt tctttaaata
     5881 ctataaataa taaatcgtct ttaataaaag atgtttgtag tattgacttt ttaaatcaag
     5941 atactatagc tatttctaat gtagaatttt gggtaaaaga gactaattcc aaatcaaagt
     6001 ctgtagattt agatttagaa aagaagaaaa tactatataa aagatatatt aagctatcac
     6061 aagatgcgaa tagtgatatt gaatcaatta gatatatgga ggaagctgta aatataggta
     6121 aaagtatgat tactaaagaa gataaagaac ttggattttg gaaaggttta tctaccagag
     6181 cctatatgat agcacttgaa tcccttgcta gaaagttaga aagtattaat aatctaaagg
     6241 agtccaaaaa agtattagaa tatttaatag aaattaatcc tagtgatgag cagggaataa
     6301 gatacaaatt attaaatgta ttaattagat taaatgatag aacttcaata aataaattat
     6361 ttgaacttta taaagaagaa aaatctgcta catggatgta cagtaaagct ctttattact
     6421 ttaaaaataa aagtatgttt ttggcaaatg attctattaa ggttgctaga agtaaaaata
     6481 agtacgttgg attatatttg ttagattggc gaaatgcttt tggtagagaa tttgttacag
     6541 aggaagaaaa ggcagaagct gtctattact atgatgaaaa catagtgatt tggaatgaag
     6601 ttaaaggttc tatggattgg ctattaaaaa aaatgttgga attttcataa aaaaaactac
     6661 tccttacttt tatataagta aaaggagtag tttttaattt atacatctag ttttaaatct
     6721 tcaggtttta ttagaccttt ttttctcata aattctgaaa tcaacaaagt tacaatagca
     6781 ggaagtataa aattaagtaa aagtatacca acccacatag atatacctcc ttttccagca
     6841 ctttgcatag cagttactgt tccaaattgt ccaaccaatc cacaagtacc cataccagaa
     6901 ccaataggaa tattctccat tttgaatatt gttgtagata atggtccaag taatattgaa
     6961 gctacagtag gtggtatcca aattttccaa ttttttatta tattaggtac ttgcaacata
     7021 gatgtcccaa gaccttgtgc cacaaggcca ccaactccat tttctctaaa gctcataaca
     7081 gcaaagccta ccatttggca acaacaacct acagttgctg caccaccagc aagaccacct
     7141 aaacttaaca tcatacaaat agctgcacta cttataggta atgtaagagc tattccaaca
     7201 agtgcagaga ctaaagctcc cattattata ggttgcatag ttgtagcttg cattattata
     7261 tttccaaatg aagtcataaa agcagaaaca gctggaccaa taagttcagc tacaagtact
     7321 ccaattagta ttgtcacagc aggtgtaacc aatatatcta tttttgtttc ttttgaaact
     7381 aattttccaa cctctacagc aaaaagtgta gcgacaaatg ctccaacagg tcctcctaat
     7441 tcattaccac aagctccaac aagtgcacaa gaaaatagta caagtggagg tgcttgaagt
     7501 ccatacgcaa tagccactgc tatagctgga ccagtaacct gtttagcaag agggcttata
     7561 acttcagtaa aaagagaaat attgaaatta tctcctaatg tattgaaaat tgttccaatt
     7621 aaaagggacg aaaaaagacc gagtgccata taacttagtg cgtcaataag atacctttga
     7681 acagaaattt caatattttt tcttttagca aatgatttga aatttctttt tttataattg
     7741 atttccaatt taaaatcctc ctcatataat ataagtataa tttcttttta attaattata
     7801 taacttttca gctgacaaga caaatgttat ttcactaaaa ttagactatt gtaatagtaa
     7861 gaaattaaca ttaattttag ttttaaattt taaatttatg gtttataatt agtataggga
     7921 tattctgaaa tataataatt ttccagttta tcccaatatt taacttaggt agattgctta
     7981 caaaacaaat gattatatat taggctaaaa ggaagtggat agatgatatt tgtaaaaaat
     8041 aagaaataca gaaaaattgc cataattata tctattccta tattgcttgt tgcgcagtac
     8101 taccttttta aatttggaat acttagacca atggtaaagg gagtagaaat tgaaattgta
     8161 gatggggaat atgttaaaga tatagataaa tatgtagtaa aattaaatga aacagttact
     8221 ttgtctacag gtgaatatat taaggttcct tcgtatgcta aaaatccaaa tatttggttt
     8281 aatgtattgg ataactcagg gactttaaaa atagatggaa ataaaatgac agcattaaag
     8341 gttgggtatt cttctgtggg tatcatgaaa aattcaagag tattaaaaaa ggctactata
     8401 aaagtagtag acccagaggt agaatcacta gatatggaga ttaatgggga tttaaaacat
     8461 gttggtgata gtgctactat agaaagtaca atagaagttg attatgataa gtttaaaaaa
     8521 tcatataagc cagtttataa gagtagcaat gaaaatattt taaaaatcaa aggaaataaa
     8581 gtaagtgcag ttggagttgg taaagctaca atatatgcta agtgtggaaa taaagaaatt
     8641 gagagaacat ttaggattca agctagagtt gctgaaataa atatggatga tataaaaata
     8701 gaagttgacc agaatgaaaa attgaaacca gatataataa cttctccacc tggtttagaa
     8761 ccaccaaaaa tatattatga gttagtagat tcaaaattac ctgtagaaag agcaataagt
     8821 ttaagtagta atggaaatgt tgtagggctt agagaaggta aagatagggt gagaataact
     8881 tgtggagata aatctaaagt aataacagta acagtagtca aagaaactat aacgaatgac
     8941 tatatacaaa acttggttgg ttcgcataaa atagtaaaca ataaagttat tattaaactt
     9001 gaatgggatt atatgaaaga tgtctttgat tatgatatat atcttaaaga taagttgtca
     9061 ggagaatcat ttaagaaaat taaatctata actataaatg aaagtgattt aggtaagtct
     9121 aacaaggtat atgcgactat agaagtagat atgaagggta atcaaaatat agattttgat
     9181 atttatgtca taggtaaaaa ggattcagat acaactaagc caagtaatgt aataaatatt
     9241 accaatggaa atggaaattc aaataatgat aataatatta aagatatgag ggtagaaaat
     9301 atatcagcta atgttgatag agataataat gtcattagag ttaactggag tagtatatct
     9361 cataaggact gtacttacag tatatatgta aaaaataata ctaatggaga tggagaattt
     9421 actctatatc aaagtgatat acagggaaat gagcatacta taagtattcc tgaaggagat
     9481 ttaaatctag atatttatgt tgttgcaaat tataatggaa atagctctca aaatagtgat
     9541 gttataaatg taagatagat ttgtatacaa attgaaagtg ttgagtttat ttaaatatta
     9601 aattaagaaa aaggatagta tagggtaatt atactatcct tttttgttac aatatatagg
     9661 tttaaaatct ctagtaatat aaattataaa aagtcttatt tacacaaatc tatagatatt
     9721 ttttttatta atcaatattg tcttaaattg aacttagtgc agcttctatt gcatgtatta
     9781 ctgtcgtatc aaatagtgga atagaagtgt cattttgttt aattaaaaga cctatttctg
     9841 tacatcctaa tataacagcc tctgcacctt gtttgccaag cttatctata atagataaga
     9901 aagctttttt tgaagattca gatataattc ctaagcaaag ttcattaaat attgtgtcat
     9961 ttactattat acggtcttct tcatttggaa ttaagacttc aattccatta ttaataatta
    10021 catttttata aaaatcttgt tccattgtat atttagtacc taataaggcc acttttttta
    10081 tttctttttc ccttaatacc gtagcagtta catctgctat gtgaagtaat ggaatatgta
    10141 tactttcttg tattttatct gataccttat gcatagtatt agtacagata acaataaaat
    10201 ctgcccctgc ctcttgtaat ttaattgcag catcagctaa aattttggcg cttttttccc
    10261 aatttccact agattggcat tcttcaattt cttgaaaatc tacactgtaa agtatacatt
    10321 tagaagagtg tagtccacct aatctttctt ttattactgt attaataact tgataatatg
    10381 taatggtact ttcccaactc ataccaccaa ttaagcctat agtcttcata ttatacctct
    10441 cttatttatt tattttgaaa tagctattta caaatacaag tatagcatct aaaatagaag
    10501 catacaataa taaaattgta tggagtacaa ttataattaa gaggagtaat tatatgccaa
    10561 taaattcttt tgaaaactat cctatgacat ggaaaccaaa gttagataac cgaaaaccac
    10621 caatatataa aactttagca atgttattag aagaagatat taaaagagga aatttaaatc
    10681 ctggagataa actgcctcca caacgggaat tagcagattt tctagattta aacttaagta
    10741 caataacacg agcatttaaa ctttgcgaag aaaagggact aatatgtgca aaagtgggaa
    10801 agggaacatt catttcttct gatgtaaatg taagtaatac attattatat caaacggaat
    10861 caaaagacat aattgagttg gggacagttc atcctccgta tgagcaaaat acatatatta
    10921 ttgactttat taaaaatgta ctaaaacaac cagaaatgga taggttttta caatacatgt
    10981 ctccatctgg cacatatatg caaaaaaagt caattgcaaa atggatagaa agaaataatg
    11041 tatacaccag tgaagaaaat atattattat ctacaggagg gcaaaatgct atatgtgcaa
    11101 ctttactagg attatttaaa gctggtgata gaattgctac agattcttta agtttttctg
    11161 gaattaagtc aatagctaaa atgataggta ttcaattagt cccaattcct caagaaaata
    11221 atgaaatatc gattgaatat cttgaaagtt attgtaaaaa tgaaaatata aaaggcatat
    11281 atcttatacc agattatcat aatccaacga cacatactat gtctgattta tctcgtaaaa
    11341 agatagccaa gatagcaaag caatacaata taataattat tgaagatgct ataaatagca
    11401 tttttagaga cggtatacaa actcccatat tttctttagc tagtgataat actatatata
    11461 tttttagtac atctaaattt ttatgtgctg gtcttagagt agcatttgta gttgctccaa
    11521 aacgatatat agaaaattta gaaaatgcac tatataatat gaatctaatg gtttctccat
    11581 ttacagcaga aatagtacac cgtttattat attctcctat tatagataaa attatagaag
    11641 agaaaagaga tgcaattata gaaagaaatg aagttgctga taaagttttg tcagattata
    11701 atttgattgg tgataagaat tgcagttttc gttggttact tcttcctgat gaattggatg
    11761 gaaaatcatt tgaaatttct gcaaaaaatc taggagttca agtatattgt gctgaacgat
    11821 tttcagtagg aaactctaca gttccaaaag cagttcgtat ttgtgtaaca gctccaaaag
    11881 atgtagaaga attagaaaaa gggcttaata taataaagtc acttcttaag agttaaattt
    11941 attttactat tatttaatta aataaataaa aaggcggaga aatttattat aataaacctc
    12001 cgcttttatt atttaatgaa atactttact ttttattaaa aaatttaatt ttaataatct
    12061 tgaaaatata atcgttttat ggtaaaataa ttcttaaaaa tagaaaaaat taatcatttg
    12121 ttaaaaaaaa tgcataattt attgtaattt attgacgaag gttgaaaaat attcataaat
    12181 gtgcgaaata acagaaaaaa tgcaaaaatt aattcaattt catttgttat aaaatctata
    12241 tggcaaaatt aaatctgcct atcagaatga tataaacaca tcagaaagga ggacgctatc
    12301 aaataataca agtagttaac tttgatagca aaaaattatg aatgaacaaa ctagaatatc
    12361 cttagagaga gctgctgaat taaaatcaaa aattgatgat tatattcagg ctagaaaaac
    12421 gattaacaga ggtcttgaaa aagaagaaga gataaataaa cgaaaacaga aaatattaag
    12481 tatcttaaat ggaactgaag aggattggaa taactacaaa tggcaattat caaatagaat
    12541 aacagatgta gatactttat caaaaattat aactctaact aaaaaagaaa aagaatatat
    12601 aaaagaggtt ggtactcaat ttagatgggc aatatctcca tattatttga gtcttataga
    12661 cccagaagat atatgtgacc caataaaatt actgtctata ccaacacata tagagttgga
    12721 agatgagcaa gaagatttgg acccaatggg agaagagtat acaaacccag caggatgtat
    12781 aactagaaga tacccggata gattaataat aaatgtaaca aatgagtgtg ctatgtattg
    12841 tagacactgt cagagaagaa gaaatattgg acaacaagat tctcataagt caaaagctat
    12901 tatccaagaa tctatagact atatcagaga aaatgaagaa ataagagatg tactagtaac
    12961 tggtggagat gctcttacat taaaagatga ttatttagag tggattctta gccaacttaa
    13021 agagatacca catgttgatt atgttagatt aggtactagg actcttgtta caatgccaca
    13081 aagaattaca gatgaatttt gcaatatgct aaaaaaatat caccctatat atataaatac
    13141 tcattttaat catccaatgg aaataactaa ggaatctaaa gaagcttgtg aaaagttagc
    13201 aaatgcaggc gttccattag gaaatcaggc agtattatta aatggaataa ataatgataa
    13261 atttgtaatg agatgtttaa atcaagaatt actgaaaata agagtaaaac cttattatat
    13321 attccaaagt aaacatgtaa agggaacaaa acatttcaat acatcagtag atgatggtct
    13381 tgaaatcatg gagtatttaa gaggatatac atcaggaatg gctataccaa catatatagt
    13441 aaatgctcca aaaggaggag gaaagactcc tttgcttcct caataccttg tatcaaaagg
    13501 aacagattac gttatgctta gaacatggga aggaaaagtt ataaaaatgg aagatgaacc
    13561 tgctgtagat ataaagaaac ttataaaaga acaagcacag gattaaaaaa atatttaaag
    13621 tttataaaaa gaaacaactt taaaataaaa agaaaatgga tgtcaaattt atatcaattt
    13681 gcatccattt tttattagtt atttattatt ttgttgttga ttaactaatt caagatatcc
    13741 acttgggtgg aagtaatata tctcagaagt attttcattt acaaagtaac caatatcacc
    13801 atctgcatct ggtaaaaata cataaccatt aagattttta gcttttaatg cttcaaaatc
    13861 actagcattt ccttgatata tgtaatcaac ttcattgttg tattttacta aaagttcttt
    13921 agcttgttct tgagtcaatt tagtattttg gcttacagga acattctttt gagaatctgc
    13981 ataagaagat tcatttactg gtgcagttaa taacaaacaa gataaaacta ataaagatat
    14041 aagtgctttt ttcatactaa aaccctcttt catgtttaat tatataagat tcattactta
    14101 ataatattgt atgtttccta taattaaata ttaccattaa agagaataat attacagtta
    14161 cacagctgta acttttgatt acaaaatcgt aattaaattg tatttttatt ccatttgtat
    14221 tttatcatgt ctacgattta caaactcaca gaagtatatc tttataacgc ccatcacagg
    14281 agcagataga atcataccag gtataccaaa gaatcctcca ccaacagtaa ctgctaggat
    14341 tgtaaagaat gggctaagac ctagttgtcc acctacgatt tttggctcta taaatgtaac
    14401 ttcaacttgt tgaattatta ttaagtaaat taaagaagtt aaagcaattg ttggattgga
    14461 gaataaatta attattacaa ctggtgccat acctattact ggaccaaaat atggaaccat
    14521 attcatgaca cccataagtg taccaaataa tagtgcatat tcagatttta aaaagtaaag
    14581 accaattcca gaaagtactc caactataaa agaatctaaa atcttacctg taaagtattt
    14641 accaatattt aaatttaagc tttgacatag ttctattata aagtctccat attttttacc
    14701 taaggaaata taaactactt tttttgtaaa cagtaagaat ttttcttttt ctaataatat
    14761 atagaaacaa attataaaac ctaaaagaaa ttgtactata aattttccaa ctgaaaatgt
    14821 agtgctaaat atcccaccaa gtgaaccaat aagcaagtta ctaaatttag gcattacact
    14881 cataattttg tcaccatact cttttaatgt attagggtca actgattgta aactcttgcc
    14941 taagtcgaat aaaaactgct ctgttttatc tatgtatgta ggaatttgag caactaaatc
    15001 agctaaacta tttactatgg atggaactgt aaataatata aacgaaatta gtataactat
    15061 gagtacacca taagtaagaa gtaacgaata tattctctta aaatttaatt tactttctaa
    15121 gaactttact agtgggttga atatatatgc taatacaaat gctattataa atggtgttag
    15181 tagtgacatt aataaactta tcactccaaa aaaatatttg taattatcaa taactttaat
    15241 caagatatat gaaacaacta cagtgagtac aatatttaga taaatttttt tatcttgcaa
    15301 aataacacaa cctttcttat atttattaaa tttagatata cttaaatcta agttaaagtt
    15361 aatatttata gcttattata caataaaaag cagtattaat atagtatgat taatatgaaa
    15421 ttataaatac gttaaaactt tatgtttata gctaaaataa taaaaattat ttatattgtg
    15481 tttatatata atctaaaatg aaaaaaagtg gtgcctttga ttaaactaag tt
//
LOCUS       DAMKNB010000084        15495 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.089, whole genome shotgun sequence.
ACCESSION   DAMKNB010000084 DAMKNB010000000
VERSION     DAMKNB010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 15495)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15495)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15495
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.089"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            178..1254
                     /locus_tag="PC494_002945"
     CDS             178..1254
                     /locus_tag="PC494_002945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HDF3913428.1"
                     /translation="MKAQRLNAVLEQMKKDDISQMLVSDPTSIFYLTGVLIHPGERLL
                     ALYLNLNGNNKLFINELFPVSEDLGVEMVWFNDTQNPVEIITEHIDKNATMGVDKNWP
                     ARFLLNLIELGGGSKFVNSSYIIDTLRMCKDEEEKELMRIASKLNDKAMEQLKATVSG
                     ELTEKQLVGKLSKIYEDLGTDGFSFDPIIGFGPNGANPHGEPGNALVKPGDAIILDIG
                     CIKDNYCADMTRTVFYKEIPEKGREIFEIVLEANKRAEAIVKPGVRFCDIDAAARDYI
                     TEKGYGQYFTHRTGHSIGLEVHDKGDVSSINTDTVQPGMIFSIEPGIYLPGEFGVRIE
                     DLVLVTEDGCEILNKHDKEICVVG"
     gene            complement(1371..2213)
                     /locus_tag="PC494_002946"
     CDS             complement(1371..2213)
                     /locus_tag="PC494_002946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HDF3913429.1"
                     /translation="MDKIKLIVDSACDLPDDIIEKYNIEVVGLNVSFGEESYISGKEI
                     DNETFYRKMSESKVLPKTSCPSPDKFLEAYHCQEESVLVINISSGLSGTYNSALLAKD
                     MFEKEGNNKKVEVIDSLSGSIGIGQLVLKAAILIKEGKEIEEIVSIINKYKDNPPFFG
                     TLETLENAIKGGRINPIAGKIINTLNFKAIIQVADGVVTPIDKARGEGNSLKKLITLV
                     ESKIKDKEEKVLFIGHANCPEKAQKVREVMEKNVKYKDVVICEIGSVMGTYTSKGAIL
                     ITAI"
     gene            2397..2969
                     /locus_tag="PC494_002947"
     CDS             2397..2969
                     /locus_tag="PC494_002947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDF3913430.1"
                     /translation="MKTNNMKQAILSSATNLIAKNGVQNTSLADIAKDVNISKGTLYY
                     HYASKDDIIYDIADTHLEVITSAILNCVKNVKSKNSQIEMVNLILEKISTIESRGRVH
                     MYLICEAITSNNDLKERIRLKYIEWRTTLKSEIVESLEKYNSSENEQDAESFSFLLMS
                     IVDGLVVQSLLKTEKIPYENIASFLVNHWI"
     gene            complement(3132..3404)
                     /locus_tag="PC494_002948"
     CDS             complement(3132..3404)
                     /locus_tag="PC494_002948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3913431.1"
                     /translation="MLRERFVVRNHHNPHTSGCCGTGGEGCCGGDNHEHSHQHSHSHG
                     HEHEHVNGVGHDHNHDDGFSGTHEHSHEHTHTHGHEHSDVHTHEHK"
     gene            complement(3531..4403)
                     /locus_tag="PC494_002949"
     CDS             complement(3531..4403)
                     /locus_tag="PC494_002949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HDF3913432.1"
                     /translation="MYGESKKLSIDNNIFLQYCLIILGMILSTLGINLYLAPAKLLSG
                     GVAGICVILYKLFGINQGISSFLMNIPIFIIARKYFDNKFLLISFVNMLLFSLALGLT
                     QDIAKYFPIDDTMLQCIYGGALTGIGMGLTFKARATAGGLDIIAAIMKRKYDIPMKNT
                     FLFINFFVVCAGAFLFGAKLVMYTLITMYIISFTMDIGKDCFDRKKSILLISNKYDEI
                     SKVIMNKMGRGVTFLEAEGAYTQNKKKMIYCIISANEIGKFKDLIYDMDSEAFISVNN
                     VEEVKGGGFKDKFL"
     gene            complement(4699..7806)
                     /locus_tag="PC494_002950"
     CDS             complement(4699..7806)
                     /locus_tag="PC494_002950"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HDF3913433.1"
                     /translation="MAKFKPLVDSSVKQAEAQVFDYWKDINILEKTLEKGKDDPSFVF
                     YEGPPTANGNPGVHHVLSRTLKDSVCRYKTMSGYQVKRKAGWDTHGLPVEIQVEKELG
                     LTSKQQIEEYGIAEFNQKCRESVFSFEKQWRIMTERMAYEVDLDNPYITLDNNYIESV
                     WWILNKFNKEGYIYEGHKILPYCPRCGTGLASHEVAQGYKEVKTNTVIAKFKKKDADE
                     YFLAWTTTPWTLPSNVSLTVNADVDYLKVKKGDEVYYVSKPLADKVLGEDYEVLEEMK
                     GKDLEGLEYEQLMPFVEVDKKAFFITVGDYVTTEDGTGIVHTAPAFGEDDYNTGKRYD
                     LPVIQPVDETGKFTSTPWEGRFVMEDGLDVEIIKWLASENKLYSKEKVVHNYPHCWRC
                     QTPLVYYAKPSWYIEMTKLKDKLIENNNGVKWFPSFVGEKRFGNWLENLNDWAISRTR
                     YWGTPLPIWRCECGHTDSVGSRAELAEKAIEDVNPETVELHRPYVDDIHLKCEKCGKP
                     MTRVTEVIDCWFDSGAMPFAQHHYPFENKENFDQLFPADYISEGIDQTRGWFYSLLAV
                     STFVLGKAPYKSVLVPDLVLDKDGKKMSKSRGNTVNPMELFDQYGADALRWYLLYVSP
                     PWTPTKFDMDGLKEIQSKFIGTMKNVYNFFTLYANTDDINPTEFFVEYKDRPELDRWI
                     LSKFNNLMKDVEENLAIFELNKTLRMIQDFINDDLSNWYIRRSRRRFWATELTEDKKA
                     VYNTTYELLHGLCRAIAPFAPYMSEEMYRNLTGEVSVHLAEYPKCNEELVDTKLEEKM
                     DLAKNLVTLGRASREVERIKVRQPLQKVLVDGKFEDTISDVVDLIKEELNVKEVIFAK
                     DLDEYMNFSLKPNFKEAGPLLGSKMNLFVGALSKLNAHETANKLEKGETLTVDLDGEA
                     FEFNKDLVLIGITAKEGFNVSVENNLFVILDTKLTEELINEGYAREFISKVQQLRKSN
                     NFEVLDNIVIEYCGDDEIAKAVDHFNEYIKSETLALEINRVDDKSLEEQNLNDHMTGI
                     KVIKK"
     misc_binding    complement(7899..8131)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(8306..8833)
                     /locus_tag="PC494_002951"
     CDS             complement(8306..8833)
                     /locus_tag="PC494_002951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DivIVA domain-containing protein"
                     /protein_id="HDF3913434.1"
                     /translation="MLTPIEIENKEFKKGLRGYRDEEVDEFLDIIKEDYESLCRENTA
                     LKEKLGLYQDQVNKYENIEETLKATLITAQSAAEDTCSAANKKAKIIVEEADLKARQI
                     IEQANNRVIEIRKEYDALVKEFKIFRNKFKSLLEDEIRSVDEIFYDVDEKCVNAFEGT
                     TVYNYSNDEAATTLE"
     gene            complement(8868..9653)
                     /locus_tag="PC494_002952"
     CDS             complement(8868..9653)
                     /locus_tag="PC494_002952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HDF3913435.1"
                     /translation="MDKLKLTNHIKDIDLKNKMFKVIDKANSCIKNYDVKSTEFLNPY
                     EVKNAVAILNSTNEIKYSVDGGYEQAERSTVFIYPFYMEYEDIEDTLRFLQIEGNFKF
                     KNISHKDYLGSILGLGIKREKIGDIIIHDSFCQVVVSSDICDFIIVNLEKVSRNNVIV
                     KEISRENIVNSSSKYKEVSFTVSSDRLDCVISGIYNISRQDSAKYINGEKVHVNYEKI
                     TSTSKIVKNDDLISIRGKGRAKVTQIGDITKKGKIKVQARLIV"
     gene            complement(9663..9920)
                     /locus_tag="PC494_002953"
     CDS             complement(9663..9920)
                     /locus_tag="PC494_002953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HDF3913436.1"
                     /translation="MGTIRIALYYLLDIIAWMIVIKSLMTWFPNGRQSKIFDILENLT
                     EPIEGPIRSIMYKYTNGPIDFSPLIAIVLLMFLRQLVLVIF"
     gene            complement(9939..10397)
                     /locus_tag="PC494_002954"
     CDS             complement(9939..10397)
                     /locus_tag="PC494_002954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HDF3913437.1"
                     /translation="MSNGIISKFKNWIVDEEEDYIEDEYESGMDDIVQEEEMNSGFST
                     AKANKIVNLHTTSQMKVVIVEPKVYDEAATIADHLKQRRAVIVNLEGLTNSEVRKSIF
                     NFMNGAVYVLDGSIQKVSKSIFILAPNNVDIDANMKKELESKAFFPWQNK"
     gene            complement(10437..11141)
                     /locus_tag="PC494_002955"
     CDS             complement(10437..11141)
                     /locus_tag="PC494_002955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HDF3913438.1"
                     /translation="MGSIKDNLSEIRNKIDKAAKKVDRDSKEITLLAVTKTVDVDLVN
                     EAMREGITSVGENKPQELARKYDIIGDKLNWHLIGTLQTNKVKYIIDKVCMIHSLDRI
                     ALCEEIQKRAEQINREIDCLVQVNISKEESKHGLDREEVVDFVKEVSEKYKNIKIKGL
                     MTMAPFIEDEDEIRGVFKGLKDLSKQIKELNIPNVGMDVLSMGMSHDYEIAIEEGATI
                     VRVGTSIFGERNYNKK"
     gene            complement(11151..11786)
                     /locus_tag="PC494_002956"
     CDS             complement(11151..11786)
                     /locus_tag="PC494_002956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3913439.1"
                     /translation="MKKVKYTRLVILGILIYLVFNILVMIISKNVDTLVLKNEKVDAK
                     IHVKGSIEKDANDQSNYLSTYISKEDSNNFEKNQNVIIEYHEQKLDAKVYKIYENNNK
                     IMVKLKISNQIVANQDTSVEEFDIIYNQMECLKIPKTSIKTKDNKRGVYVIDEQSQSV
                     KFVILEGITYENESSVFVDYYKNDINGVTSVNLYDKIILRPNSINTNIRIK"
     gene            12167..13207
                     /locus_tag="PC494_002957"
     CDS             12167..13207
                     /locus_tag="PC494_002957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDF3913440.1"
                     /translation="MSEILLGTGLLLLVLCCFTIFSYKAPYGMKAMGALANAACATFL
                     VEAFNLSLLGDVLGMEFFRSVGAANGSLGGVAAAILVPLALGVSPVYAVLIGLSCLDF
                     SILSGFVAGYFVSFLIKFIEKKVPPGVDLVVVILLCAPLSRLIASNVDPLVNSTLLQI
                     GQVLIEATNISPIIMGIILGGLITVVGTSPLSSMALTSIIGLTGLPMAIGALGAFGSA
                     FMNSTLFAKLKLGSKKDIISVAIEPLTQSDIISANPIPIYSTNFFGGAFSGIIVALMG
                     LVNMTPGTATPVAGFAIMFAYNPVQQVLITAGLCALFNVIAGFLGSKIFSTFKVLTAG
                     EIRGTDVEEEIA"
     gene            complement(13670..15025)
                     /locus_tag="PC494_002958"
     CDS             complement(13670..15025)
                     /locus_tag="PC494_002958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009170073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PFL family protein"
                     /protein_id="HDF3913441.1"
                     /translation="MNVGNILETIKMIDEEQLDIRTITMGISLLDCIDPDGDKAREKI
                     YNKIMSSAKDLVKVGKDIEREFGIPIVNKRVSVTPISIIAGATDENDYVKFAQTLDKA
                     AEDLGIDFIGGFSALVQKGYTKGDKILIKSIPKALASTNKVCASVNVGSTRCGINMDA
                     VKEMGEIIKETAELTKDAKGFGCAKLVVFCNAVEDNPFMAGAFHGVGEADRIINVGVS
                     GPGVVKRALEKVKGEPFDVVSETVKKTAFKITRVGQLVAKEASSRLDVPFGIIDLSLA
                     PTPAIGDSVANILEEMGLEVVGTHGTTAALALLNDAVKKGGVMACSHVGGLSGAFIPV
                     SEDAGMIDAVIKGALSIDKLEAMTAICSVGLDMIAVPGNTTAGTLGAMIADEAAIGMI
                     NNKTTAVRIIPAPGCDVGDMVEFGGLLGRAPVMPINTNSSELFTQRGGRIPAPIHSFK
                     N"
     gene            complement(15051..15320)
                     /locus_tag="PC494_002959"
     CDS             complement(15051..15320)
                     /locus_tag="PC494_002959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010963800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HDF3913442.1"
                     /translation="MKAILTVIGKDKPGIVAGISDELYKQNINIVDISQKILQDYFTM
                     IMIVDLEKSLNSFEKTVEDLVERGKKLSVDVKIQREEIFNSMHNL"
BASE COUNT         4918 a         2695 c         1797 g         6085 t
ORIGIN      
        1 gaattttcac aataaaaagt cattttactt ccgtatttaa tgcaaaagta gagattaaac
       61 ttaatataaa aaatatataa caaatttttt ttatatttct agaagaaaag tatactcttt
      121 tttgtttaat aatgctaaaa ttgatttgta ttgaattttg attaggagga aattattatg
      181 aaagctcaaa gattaaatgc tgtacttgaa caaatgaaaa aagatgatat ttctcaaatg
      241 ttagtaagtg accctacttc tatattttat cttacaggag tactaatcca tccaggcgaa
      301 agactattag cattatactt aaatttaaat ggcaataata aattatttat aaatgaatta
      361 ttcccagttt cagaagattt aggtgttgaa atggtttggt ttaatgatac tcaaaatcca
      421 gtagaaataa taactgaaca tatagacaaa aatgctacta tgggtgttga taaaaactgg
      481 ccagctagat tcttattaaa cttaatagaa ttaggtggag gaagtaagtt tgtaaattca
      541 tcttatataa tagatacttt aagaatgtgt aaagatgaag aagaaaaaga gttaatgaga
      601 atagcttcaa aattaaatga caaggctatg gaacaactta aagctactgt ttctggtgaa
      661 cttacagaaa aacaacttgt tggtaaatta tctaaaatat atgaagacct aggtactgat
      721 ggattttcat ttgaccctat tataggtttt ggacctaatg gagctaatcc acatggtgaa
      781 cctggaaatg cacttgtgaa accaggagat gcaataatct tagatatagg ttgtataaaa
      841 gataactatt gtgctgatat gacaagaact gtattctata aagaaatacc tgaaaaaggt
      901 agagaaatat ttgaaatagt tcttgaagct aataagagag ctgaagctat tgtaaaacca
      961 ggtgttagat tctgtgatat agatgctgct gctcgtgact acataactga aaagggatat
     1021 ggacagtact tcactcatag aactggtcac tctataggac ttgaagttca tgataaagga
     1081 gatgtatctt ctataaatac agatactgta caaccaggaa tgatattctc tatagagcca
     1141 ggtatatatt taccaggtga gttcggagtt agaatagaag atttagtact tgttactgaa
     1201 gatggttgtg agatattaaa caagcatgac aaagaaatat gtgtagttgg ttaattctaa
     1261 aatcaatttg ataaaattaa aaagccatat aaaaatgttt taaacatttt tatatggctt
     1321 taatttctca atctattatt tatttcaatc cattatttat attgcagtat ttatattgca
     1381 gttattaaga ttgcaccctt tgaagtatat gtccccatca ctgaaccaat ttcacagatt
     1441 acaacatctt tgtattttac attcttttcc ataacttccc ttaccttttg agccttttct
     1501 gggcaattag catgtcctat aaataaaacc ttttcttctt tatctttaat ttttgactct
     1561 actaaagtaa tcagcttttt caaactgttt ccttcacctc ttgccttatc tataggagtt
     1621 acaacgccat ctgcaacttg tattatcgcc ttaaaattta aggtatttat aatttttcct
     1681 gctattggat ttattctacc acccttaata gcattttcta aagtttcaag tgttccaaaa
     1741 aatggaggat tatctttata tttatttatt attgaaacaa tctcttcaat ttcttttcct
     1801 tcttttatta atattgctgc ttttaacact aattgtccta ttccaattga cccactaagt
     1861 gaatctataa cctcaacttt cttgttattt ccttcctttt caaacatatc ttttgctaaa
     1921 agtgcactat tataagtccc agataatcct gaacttatat taatcactaa tacactttct
     1981 tcctgacaat ggtatgcttc taaaaattta tcaggagaag gacatgatgt ttttggtagt
     2041 actttactct cactcatttt tctatagaaa gtttcattat ctatttcctt tccagatata
     2101 taactttctt ctccaaaaga tacatttaaa ccaacaactt ctatgttgta tttttctatt
     2161 atatcatcag gtaagtcaca tgcactgtcc actatcaatt ttattttatc catattaacc
     2221 tcactataag atattatttt atttattcag tcggtcgtac gaccgattta attattattt
     2281 tatatattga atgaaaaaaa gtcaatagat atagattctc gctttattga caataaatat
     2341 ccataagctt ataatgttat taatttgtta taaatataca tggaaaggta ggttttatga
     2401 aaacaaataa tatgaaacag gctattttat catctgcaac caatttaata gccaaaaatg
     2461 gagttcaaaa tactagcctt gctgatattg caaaagatgt aaatataagt aaaggtactt
     2521 tgtattatca ctacgcatct aaagatgata ttatatatga tattgcggat actcatttag
     2581 aagttataac tagtgctata ctaaactgtg taaaaaatgt caaatcaaaa aattctcaaa
     2641 tagaaatggt taacttaatc ttagagaaaa tatctactat agaaagtcgt ggtagggtac
     2701 atatgtatct tatttgtgag gcaattactt caaataatga tttaaaggaa agaataagat
     2761 taaaatatat tgaatggaga actactctta aatctgaaat tgttgaatca ctagaaaaat
     2821 ataatagtag cgaaaatgaa caggatgctg aatcattttc ttttttactc atgtcaatag
     2881 ttgatggttt agttgtccaa agtttattaa aaacagaaaa aataccttat gaaaatatag
     2941 cttctttttt agttaatcat tggatttaaa cttaatactt agataattaa taaaagtgaa
     3001 ctatttaagt tatctacttt aacagttcac tttcttattt attctcaata atttttactt
     3061 aaaacattca atttttattt aaaccttcat ggaatcacaa aataaaaatc tcttataaat
     3121 ttaaaatgtt tttatttatg ttcatgtgta tgcacatctg aatgttcatg accatgtgta
     3181 tgtgtatgct catggctatg ctcatgagta cctgaaaaac catcatcatg attatggtcg
     3241 tgacctacac catttacatg ctcatgttca tgcccatgac tgtgagaatg ttgatgtgaa
     3301 tgttcatggt tatctcctcc acagcatcct tctcctccag tcccacaaca cccacttgta
     3361 tgtggattat gatgatttct tactacaaat ctctctctta acataattct tatacctcct
     3421 agtatattat tgagtacttc atgtacccca ttaactacag tatacatcta actaggtata
     3481 atctcaatac atatggcatt ttttaacata tataattaac atatataatc ttaaagaaat
     3541 ttatccttaa aacctccacc ttttacttct tcaacgttat tgacagaaat aaaagcttca
     3601 ctatccatat cataaattaa atctttaaat ttacctattt catttgcaga tattatgcaa
     3661 taaatcatct ttttcttatt ttgtgtatat gcaccttctg cctccaaaaa agtgactcct
     3721 ctacccattt tattcattat cactttggat atttcatcat atttatttga tattaaaagt
     3781 atagattttt ttctatcaaa gcaatctttt cctatatcca tagtaaaaga aattatatac
     3841 attgtaatta aagtgtacat caccaattta gctccaaata aaaaagctcc tgcacatact
     3901 acaaaaaaat taataaataa aaatgtattt ttcataggta tatcatactt tcttttcatt
     3961 atggctgcta ttatatcaag tcctccagca gtagctcttg ctttaaaagt taaccccata
     4021 cctataccag ttaatgcacc accataaata cactgtagca tagtatcatc tattgggaaa
     4081 tatttagcaa tatcttgtgt tagccccagt gctagagaaa atagtaacat attgacaaaa
     4141 cttattagca aaaatttatt atcaaaatac tttctagcta taataaatat tggtatgttc
     4201 atcaagaaac ttgatattcc ctgattaata ccaaataatt tgtataatat aacacaaatt
     4261 ccagctactc ctccacttaa taacttggct ggtgctagat ataaatttat tcctaaggtt
     4321 gatagaatca tacccaatat aataagacaa tattgtaaaa atatattatt atcaatactt
     4381 agctttttac tttcaccata catcaaaacg cacccctttg cataataaat aaaccaccct
     4441 gcataacaca cgataaattt acaaataaat ttatcagaag tagtttccta aaaatattat
     4501 tcatcctcac ttaaacgttt attcattaat attctatcac atgacataaa taatttatat
     4561 gatttatata gatttattta ttgtaaattt tggaatatta aaacatttta ttgaatagat
     4621 aattatatta cataaaaaat ccctatagaa atctataaac taatttctat agggattttg
     4681 gttaactaac tattattttt atttttttat aacttttata cctgtcatat ggtcatttaa
     4741 gttttgttcc tctaaagatt tatcatctac tctgtttatt tctaaagcta aagtttcaga
     4801 cttgatatat tcattaaaat ggtcaacagc cttagcaatt tcatcatcac cacagtattc
     4861 tattactata ttatctaata cttcaaagtt attagatttt cttaattgct gtactttaga
     4921 tataaattct ctagcataac cttcattaat caactcttca gttagcttag tatctagtat
     4981 aacaaaaaga ttgttttcaa cagatacatt aaatccttcc ttagcagtta tacctattaa
     5041 tactaaatcc ttattaaatt caaaagcttc accatctaaa tcaactgtta aagtctcacc
     5101 tttttcaagt ttattagcag tttcatgagc atttaattta cttaatgctc caacgaataa
     5161 attcatctta gaacctaata atggccctgc ttccttaaag tttggtttta aactaaagtt
     5221 catatactca tctaaatcct tagcaaatat tacctcttta acattaagct cttcttttat
     5281 taaatcaact acatcactta ttgtatcttc aaacttacca tctactaaca ctttttgtaa
     5341 tggttgacga acttttattc tttctacttc tcttgaagct ctacctaaag taactaagtt
     5401 tttagctaaa tccatttttt cttctaattt agtatctact aactcttcat tacatttagg
     5461 atattcagct aaatgaacag atacttctcc tgttaagttt ctatacattt cttctgacat
     5521 atatggtgca aatggagcta tagctctaca aagaccatgt aacaattcat aagttgtatt
     5581 gtacactgct tttttatctt ctgttaattc agttgcccag aatcttcttc ttgaacgtct
     5641 tatataccag ttagataaat catcatttat aaaatcttgt atcattctta aagttttatt
     5701 taactcaaat atagctaaat tttcttctac atctttcatt aaattattga acttagataa
     5761 tatccatcta tcaagttctg gtctatcttt atattctaca aaaaattcag ttggatttat
     5821 atcatctgtg tttgcatata aagtaaagaa gttatataca ttcttcatag tacctataaa
     5881 tttactttgg atttctttta atccatccat atcaaattta gttggagtcc atggtggaga
     5941 aacatatagt aaataccatc ttaatgcatc tgctccatat tggtcaaata attccattgg
     6001 atttactgta tttcctcttg atttactcat tttcttacca tctttatcaa gtacaaggtc
     6061 tggaactaaa acactcttat atggtgcttt tcctaataca aatgttgata ctgcaagtaa
     6121 tgagtagaac caacctctag tctggtctat accttctgat atatagtcag ctgggaacaa
     6181 ttggtcaaag ttttccttat tttcaaatgg atagtggtgt tgagcaaatg gcatagcccc
     6241 actatcaaac caacagtcta taacctctgt tactcttgtc attggttttc cacatttttc
     6301 acattttaag tgtatatcat ctacatatgg tctatgaagt tcaactgttt ctggatttac
     6361 atcttctata gctttttcag ctaattcagc tcttgaacca actgaatctg tatgaccaca
     6421 ttcacatctc catataggaa gtggagttcc ccaatatcta gttcttgata ttgcccagtc
     6481 atttagattt tctaaccagt ttccaaatct cttctctcct acaaaacttg ggaaccattt
     6541 tacaccatta ttattttcta ttaatttatc tttaagttta gtcatctcta tataccagct
     6601 tggttttgca tagtatacta atggagtttg acatctccag cagtgtggat aattatgaac
     6661 tactttttct ttgctatata atttattttc agaagctagc cattttatta tttcaacatc
     6721 tagcccatct tccattacaa atctaccttc ccaaggagta gatgtaaatt taccagtttc
     6781 atctactggt tgaataactg gtaaatcata tcttttacct gtgttgtagt catcttcacc
     6841 aaatgctggt gctgtatgaa ctataccagt tccatcttca gtagttacat aatctcctac
     6901 tgtaataaaa aatgcttttt tgtcaacttc tacaaaaggc attaattgtt catattctaa
     6961 accttctagg tctttacctt tcatttcttc taaaacttca taatcttcac ctagtacttt
     7021 atcagctaaa ggtttagata cataatatac ctcatcacct tttttaactt ttaaataatc
     7081 tacatcagca tttactgtta atgaaacatt tgatggtaaa gtccatggag ttgttgtcca
     7141 tgctaagaag tattcatcag catctttttt cttaaattta gctataactg tattagtttt
     7201 tacttcttta tatccttgtg caacctcatg actagcaaga ccagttccac atcttgggca
     7261 ataaggaagt attttatgcc cttcatatat atatccttct ttgttgaatt tgtttagtat
     7321 ccaccataca gactctatat agttattatc taaagttata tatggattat ctaaatcaac
     7381 ttcataagcc attctctcag tcattattct ccattgtttt tcaaatgaga aaactgactc
     7441 tctacatttt tggttaaatt cagctattcc atattcttct atttgttgct tactagtaag
     7501 tcctaactct ttctctactt gtatttcaac tggtaatcca tgtgtatccc aaccagcttt
     7561 tctctttact tgataaccag acattgtttt atatctacaa actgaatctt taagcgttct
     7621 agataaaaca tggtgtactc caggatttcc attagctgtt ggaggtcctt catagaatac
     7681 gaaacttggg tcatctttcc ctttttctaa agttttttca agtatattta tgtctttcca
     7741 ataatcaaaa acttgtgctt ctgcttgttt tacagaactg tctaccaatg gcttaaattt
     7801 cgccatgtaa atcacccttt cctactaaat attataattc caaaattttt tattctttca
     7861 cataaattta aatactaaaa aactcgcccc ctttaaacca aagggacgag ttataaatcg
     7921 cgttaccacc ctaattctat atgtaaacta aatactagct acatataaca ctctaatagt
     7981 ataacggtac taaccggcac agcttagtag aatttaatcg ttcagcctgc agctcaagag
     8041 tgatttttat ctttataaat tcattggttc tcagcatacc caattctctg taaaattatc
     8101 taaagataaa tgtctctatc aacgctttta aaaatttatc tgtgtttata tgaaattcta
     8161 taacaaataa tttgaatagt caatatattt ttgaaaaata taataatttc tatttttctt
     8221 acatttttat cctattttta atttttgtta tagatttctc aaactcacac aattattcta
     8281 cataaaaaat aaacaaatta caagcttatt ctaaagttgt agcagcttca tcattactat
     8341 aattatacac tgttgttcct tcaaatgcgt ttacacattt ttcatctaca tcataaaaaa
     8401 tctcatcaac acttcttatt tcatcttcta acagtgattt aaatttattt ctaaatatct
     8461 taaattcttt gactaaagca tcatactctt ttcttatctc tataacacgg ttattagctt
     8521 gttctataat ttgtctagct tttaaatcag cttcttcaac aattatctta gcctttttat
     8581 tagccgcgct acaagtgtct tctgctgcac tttgagcagt tattaaagta gcttttagtg
     8641 tttcttcaat attttcatac ttgtttactt ggtcttgata taaccctaat ttttctttaa
     8701 gagctgtatt ttccctacat agagattcat aatcttcctt gatgatatct aaaaattcat
     8761 caacctcttc atctctatac cctcttaaac cttttttaaa ctctttattt tctatctcaa
     8821 ttggagttag cattacattt cctcccagct ataatttaaa ttagtcctta tacaattaat
     8881 cttgcttgaa cttttatttt tcctttttta gtaatatctc ctatttgtgt taccttagct
     8941 cttcctttgc ctctaataga aatcaaatca tcgtttttta ctattttaga agttgaagtt
     9001 atcttttcat aattgacatg gactttttct ccatttatgt attttgcact atcttgtcta
     9061 gatatattgt aaataccact tatcacacaa tctaacctat ctgaagatac tgtaaatgat
     9121 acttctttat attttgaaga actattaaca atattttctc tggaaatttc ctttacaatt
     9181 acattatttc ttgaaacctt ttctaagttt acaattataa aatcgcaaat atcactactt
     9241 acaactactt gacaaaagct atcatgtata attatatctc caattttttc tctttttata
     9301 cctagaccca gtattgaccc taagtaatct ttatgagata tatttttaaa tttgaaattc
     9361 ccttctattt gtaaaaatct aagagtatct tctatatctt catattccat gtaaaatgga
     9421 taaataaata cagtgcttct ttcagcttgt tcataacctc catccacact gtattttatt
     9481 tcatttgtag aatttaatat tgctacagca tttttcactt catatggatt aagaaactcc
     9541 gtagacttaa catcatagtt ttttatacaa ctattagcct tgtctatcac tttaaacatt
     9601 ttatttttca agtctatatc ctttatgtga tttgttagtt ttaatttatc catcctatca
     9661 ccttagaata taaccaatac taattgtctt aggaacatca ataatactat tgcaattaaa
     9721 ggagaaaaat ctataggtcc atttgtatat ttatacatta tagaccttat tggcccttct
     9781 attggctctg taagattttc caaaatatca aaaattttac tttgtcttcc atttggaaac
     9841 caagtcatca agctttttat aactatcatc catgctatta tatctaaaag ataataaagt
     9901 gcaattctta ttgttcccat atattaaccg cctttttact atttattttg ccaagggaag
     9961 aatgctttac tttctaattc ttttttcata tttgcatcta tatccacatt attaggagct
    10021 agtataaata ttgatttaga aaccttttgt atacttccat ctaagacata aactgcccca
    10081 ttcataaagt taaatataga tttgcgaact tcagaattag tcaatccttc caaattcact
    10141 ataactgccc ttctttgttt tagatggtct gctatagttg cagcttcatc ataaacctta
    10201 ggttcaacta ttacaacttt catttggcta gttgtatgta aatttacaat tttatttgct
    10261 tttgcagtac taaagccact gttcatttct tcttcttgaa ctatatcgtc catgccactt
    10321 tcatattcat cttcaatgta atcttcttct tcatcaacta tccaattctt aaatttagat
    10381 attattccat ttgacattat taacttcctc cttaaaattt attcaaattt gagtaattat
    10441 tttttattgt agtttctttc tccaaagatt gatgttccaa ctctaacaat ggtagcccct
    10501 tcctctatag caatttcata atcgtgactc attcccattg acaaaacatc catccctaca
    10561 ttagggatgt ttagttcttt tatttgtttt gataaatctt taagaccttt aaatacacct
    10621 cttatctcat cttcatcttc tataaaaggt gccattgtca ttagaccctt tatttttata
    10681 tttttatatt tttctgacac ttctttgaca aagtctacaa cttcttctct atcaagtcca
    10741 tgcttagact cttctttaga tatattcact tgtactaagc aatctatttc tctgtttatt
    10801 tgttctgcac gtttttgaat ttcttcgcat aatgcaattc tatctaaaga gtgtatcata
    10861 caaactttat cgattatgta cttaacttta ttggtttgca aagttcctat caggtgccag
    10921 tttaatttat cacctataat atcatacttt ctagctaatt cttggggttt attttcacca
    10981 acagaagtga ttccttccct cattgcctca ttaactaagt ctacatcaac agtctttgtg
    11041 actgccaaaa gggtaatctc tttgctgtct ctatctactt tttttgcagc tttatcaatt
    11101 ttgtttctta tctcagacaa attatcttta atagaaccca ttattatcac ctactttatc
    11161 cttatatttg tgtttatact gttaggtctt aaaattattt tgtcatatag attaacactt
    11221 gtaactccat ttatgtcatt tttataataa tccacaaata cagaagattc attctcataa
    11281 gttattcctt ctaatatgac aaattttaca ctttgtgatt gttcatcaat tacatataca
    11341 ccacgtttat tgtcttttgt ttttatagaa gttttaggta tttttaaaca ttccatctga
    11401 ttatatatta tatcaaattc ttcgacactt gtatcctgat ttgcaacaat ttggttactt
    11461 atttttaatt ttaccattat tttattatta ttttcatata ttttgtaaac ttttgcatct
    11521 aatttttgct catgatattc aattattaca ttttgatttt tttcaaagtt attagaatct
    11581 tctttactga tgtatgtaga tagataatta ctctggtcat tggcatcttt ttctatactt
    11641 ccttttacat gaatctttgc atcaactttt tcatttttta acaccaacgt atctacattt
    11701 ttgctaatta tcattactaa tatattaaat actaaatata taagaatacc aagtatcact
    11761 aatctggtat attttacctt tttcaaagac tctcccccta taaaattact ttcattataa
    11821 gtacttcttc taaaaaatgt ttattccttt tttataagct aatattttac gttctaataa
    11881 ttattttttc catattaaat ttatttttta tcaatcttcc tatacaagac tgcattattt
    11941 atatataatt gtattataaa gtataagttt aatttacatt ttatacgtta agcttacttt
    12001 atatgttttt atagttattt ttatttttag atgcaatata aaaccaatta agatttaaaa
    12061 taacttttgt tatgttgaca tttatttagg taatcattta tgaattagga taacgttatc
    12121 ataacaaaag tttatgtcct aaaaaaaata caaggaggat tttcttatgt cagaaatttt
    12181 attaggaaca ggtttacttt tattggttct atgttgtttc acaattttta gttacaaggc
    12241 cccatatggt atgaaggcta tgggagctct agcaaacgct gcatgtgcta ctttcttagt
    12301 agaggcattc aacctttctt tacttggtga tgttttaggt atggaatttt ttagaagtgt
    12361 tggagctgct aatggtagtc ttggtggagt tgctgctgct atacttgtgc ctttagcctt
    12421 aggtgtatct ccagtttatg cagttttaat aggattatct tgtttagatt tttctatatt
    12481 atctggattc gttgctggat actttgtttc tttcttaatt aagtttatag agaaaaaagt
    12541 gccacctgga gtggatttag tggttgtaat tcttctatgt gcaccgctat ctcgtcttat
    12601 agcatcaaat gtagacccat tagttaatag tacactacta caaattggac aagttttgat
    12661 agaagctacc aacattagcc ctataataat gggaattata ctaggaggtc taataacagt
    12721 agttggaacg tctccactta gttcaatggc tcttacatct ataattggtc ttactggtct
    12781 tcctatggca ataggagcat taggtgcttt tggttcagct tttatgaact caacactatt
    12841 tgcaaaattg aaattaggtt ctaaaaaaga tattatatct gttgctattg aaccattaac
    12901 ccaatcagac ataatttcag ctaatccaat acctatatat tctactaatt tctttggagg
    12961 agccttttct ggtatcattg tagccttgat gggtcttgta aacatgacac caggtacagc
    13021 tacacctgtg gctggttttg ctataatgtt tgcttataat ccagttcaac aagttcttat
    13081 aacagctggt ttatgtgctt tattcaatgt aattgcagga tttttaggtt caaaaatatt
    13141 cagtaccttt aaagttctta ctgctggtga aatacgtggt actgatgtag aagaagaaat
    13201 tgcttaaaaa acaataagat ttataaattt atatctcaag tagtagagtt ttatattgta
    13261 ggcaatttta ttaattgcaa acgttttatt ttttatttat gtttatgatt attatgtgtg
    13321 ttgaatattt agataaattt ttatttatta tttttattta gatttttgtt tagtttttta
    13381 tttggttgat atattaggaa taaaaattag tatagtttat tactagttaa gtagcataac
    13441 tttttagata cataaaaaat tttatattaa ttagatatta ttaaaataaa agcgatacat
    13501 gaatttttaa atgtccatgt atcgctttat ttttgccata atcttaacaa ctgattttta
    13561 aagtttatta tcttaacaaa gttcattatc ttatataata tttaaatgca taggcttctt
    13621 taatttaacc atctaaatat ttaattaaat attattatat gtaatataac taatttttaa
    13681 atgaatgtat aggagctgga atccttcctc ctctttgagt aaataattca gatgaatttg
    13741 tatttatagg cattactggt gctcgtccta aaagtcctcc aaattctacc atatcaccta
    13801 catcacatcc tggggctggt ataattctaa cggctgtagt cttattatta atcataccta
    13861 ttgctgcctc atcagctatc atggctccaa gcgtacctgc tgtagtattt cctggcacag
    13921 ctatcatatc aagacctaca gaacaaatag cagtcattgc ttcaagctta tctatactta
    13981 aagcaccttt aataacagca tcaatcatac ctgcatcttc agatactggt ataaacgctc
    14041 cactaagtcc tccaacatgt gaacatgcca ttactccacc ttttttaaca gcatcattta
    14101 aaagtgctaa tgctgctgta gtcccatgag taccaacaac ttcaagaccc atttcctcta
    14161 atatatttgc taccgaatca ccaatagcag gtgtaggagc tagtgataag tctattatcc
    14221 caaatggaac atccaatcta ctagaagctt cctttgccac aagttgtcca actcttgtaa
    14281 ttttaaatgc agtcttttta actgtttctg aaacaacatc aaaaggctct ccctttactt
    14341 tctctaaagc tctcttaaca acaccagggc cacttacacc aacatttata attctatcag
    14401 cctcaccaac accatggaaa gctcctgcca taaatggatt atcttctact gcattacaaa
    14461 atactactaa ttttgcacaa ccaaaacctt ttgcatcttt tgttaattct gcagtttctt
    14521 ttatgatttc tcccatttct ttcactgcat ccatatttat accacatctt gtagaaccta
    14581 catttactga agcacatact ttattagtac ttgctagagc ttttggaatt gacttaatta
    14641 gtatcttatc accttttgta tatccctttt gaactaatgc tgagaatcca ccaataaaat
    14701 ctatacctaa atcctctgca gccttatcca atgtctgtgc aaactttaca tagtcatttt
    14761 catctgttgc acctgcaata atggaaattg gagttactga taccctttta tttacaattg
    14821 ggataccaaa ttcacgctct atatcttttc caaccttcac caaatcttta gcagaactca
    14881 taatcttatt gtatattttt tctctagctt tatctccatc agggtctata caatctaata
    14941 aagaaatccc catagttata gttcttatat ccaactgttc ttcatctatc atctttattg
    15001 tttcaagtat atttcctaca ttcactatta tcacctcccc ttactgtcta ctacagatta
    15061 tgcattgaat taaatatttc ttctcgctga atttttacat ccactgataa tttcttacct
    15121 ctttcaacca agtcctcaac cgttttctca aaagaattta atgatttctc taaatcaact
    15181 atcataatca tagtaaaata atcctgtaat attttttgtg atatatctac tatgttgata
    15241 ttttgcttgt ataattcatc actaattcct gccactatac ctggtttatc ctttccaatt
    15301 actgttaaaa ttgctttcat aataatatcc tcccttattt ttttataaat cttatatttt
    15361 tacaaattga actatgtgtt aacatatatt tcatttattt gttagtaaac cactttttat
    15421 gtatatattt aatatatttt aatacctata cattcatttg tcaatttttt ttcaatattc
    15481 tattattttt atact
//
LOCUS       DAMKNB010000085        15462 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.090, whole genome shotgun sequence.
ACCESSION   DAMKNB010000085 DAMKNB010000000
VERSION     DAMKNB010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 15462)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15462)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15462
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.090"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            184..1635
                     /locus_tag="PC494_002960"
     CDS             184..1635
                     /locus_tag="PC494_002960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine:cation symporter family protein"
                     /protein_id="HDF3913443.1"
                     /translation="MDFFNGILTSINNAVVYVNNYLWSYILIIMLVVIGIYFTIKTNF
                     VQFRYFIEMFRLLGDGTANKNAKKEGKISSFQAFCISTSSRVGTGNIAGIAIAVVAGG
                     PGAVFWMWLIALIGSASSFVESTLAQIYKVKDGQAFRGGPAYYMEQGLNKKWMGILFS
                     ILITICYGFVFNAVQANTVSLAFNNAFGISKMAMGIGLGILTAIVIFGGVHRVAKVSE
                     IIVPVFAGLYILVALAIVVMNITEIPSVIALIVESAFDFKGMAIGTFMGVVMTGVKRG
                     LFSNEAGMGSAPNAAATAHVTHPVKQGLIQSLGVFTDTIIICSCTAFMVLLYSGYSSS
                     GATGIELAQEALTHHIGPVGNIFIAVCIFLFAFSSIVGNYYYGESNMEFMSGSKTKLN
                     VFRVFVVGMVLFGSLTQVDVVWNLADLFMALMAIINLIAIALLGKYAFIALKDYTSQK
                     KSGIKDPVFIADEIEGLEKVSEWHRELSEEHLG"
     gene            complement(1854..2315)
                     /locus_tag="PC494_002961"
     CDS             complement(1854..2315)
                     /locus_tag="PC494_002961"
                     /EC_number="2.5.1.78"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6,7-dimethyl-8-ribityllumazine synthase"
                     /protein_id="HDF3913444.1"
                     /translation="MIYEGKLIGKDLKIGIINSRFNEFITSKLLSGAEDCLLRHDVSP
                     ENIEIVWVPGAFEIPLVAQKMAKSGKYDAIICLGCVIRGATSHYDYVCSEVSKGIAKV
                     SLDSELPVIFGIVTTENIEQAIERAGTKAGNKGYDCAMNALEMANLFKSLN"
     gene            complement(2420..3613)
                     /locus_tag="PC494_002962"
     CDS             complement(2420..3613)
                     /locus_tag="PC494_002962"
                     /EC_number="3.5.4.25"
                     /EC_number="4.1.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP
                     cyclohydrolase II"
                     /protein_id="HDF3913445.1"
                     /translation="MFNTIEEAIEDIKNGKMVIVVDDESRENEGDLLMAAEMATPESI
                     NFMATYGRGLICLPATEKKFKSLNIPLMVRENTDTFQTAFTVTIDGADTLTGISAYER
                     AETVKLFCDENSTSKDFKTPGHIFPLIAKTGGVLVRDGHTEASVDLARLAGFKEIGLI
                     CEIMKDDGTMARVDDLMIFKEKHNLKIITIKDLIEYRKINETTIEKVSSAFLPTKYGN
                     FEIIGYRDTYSNEEHIALTYGNINIENTLVRLHSECLTGDVFHSLKCDCGLQLESSMK
                     KIVENGSGVLIYMKQEGRGIGLLNKIKAYKLQEEGYDTVEANLMLGFEEDMRDFYMAA
                     QILKNLNIKSINLLSNNPDKINQLEKYGIKIENRIPINEEINDFNKLYLKTKKDKMGH
                     LLDII"
     gene            complement(3636..4301)
                     /locus_tag="PC494_002963"
     CDS             complement(3636..4301)
                     /locus_tag="PC494_002963"
                     /EC_number="2.5.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin synthase"
                     /protein_id="HDF3913446.1"
                     /translation="MFTGIVEEVGILRKITANGKSGKVTILSNKILDGTNLGDSIAVN
                     GVCLTVSNLGKNEFTADVMMETIRSTNLGLLNANDKVNLERAMSLSSRFGGHIVTGHV
                     DGKGTICKFEKDENAVLVSIRPDKKLLSSMILKGSVAIDGVSLTISYLDDEIFKVSII
                     PHTKINTILLTKNVGDFVNLESDVIGKYVNNFMANNYKELNSNSNNHKSNIDKDFLFK
                     NGF"
     gene            complement(4335..5447)
                     /gene="ribD"
                     /locus_tag="PC494_002964"
     CDS             complement(4335..5447)
                     /gene="ribD"
                     /locus_tag="PC494_002964"
                     /EC_number="1.1.1.193"
                     /EC_number="3.5.4.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     diaminohydroxyphosphoribosylaminopyrimidine
                     deaminase/5-amino-6-(5-phosphoribosylamino)uracil
                     reductase RibD"
                     /protein_id="HDF3913447.1"
                     /translation="MNFVNQKEKDIYYMKKAIELAKNGEGFVNPNPLVGCVIVKASNI
                     IGKGYHEKFGSNHAEVNAINSAKQSLKDSTLYVNLEPCSHYGKTPPCVDKIIQNKIKR
                     VVISTLDPNPLVCGNGVKKLKDNNIDVTVGILEDEARDLNEAFFYHIKNKRPLCIVKS
                     AVSLDGKIATKSLESKWISNESSRYLTHKYRNKYQSIMVGINTVLNDNPLLTCRLNQE
                     KVSHPTRIVIDTHLKLPLNSNLVKDKTSKTIVFTCCKESIKLSMLKENNVETIISPSK
                     NNLVDLEFVMYKLGELNIDSVLVEGGATLNDSLFRNKLVDKVKLFLSPKIIGGKDAPT
                     FVSGEGINHLSDSTQLTINNVTLIDGDILIESDVLN"
     regulatory      complement(5579..5700)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            5889..8372
                     /gene="recQ"
                     /locus_tag="PC494_002965"
     CDS             5889..8372
                     /gene="recQ"
                     /locus_tag="PC494_002965"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase RecQ"
                     /protein_id="HDF3913448.1"
                     /translation="MNKKLLEILSKYYGYTSFRKGQESIINSILSEKDVLAIMPTGGG
                     KSICYQIPALILDGMTIVISPLISLMKDQVDALKTMGISAAFINSSLSSKEFNEILNN
                     IRKNNYKILYIAPERLDAQEFIELINNNNVSQVAIDEAHCVSQWGHDFRLSYRRISDF
                     IKNLPKRPIVTAFTATASEEVRTDIINLLCLENPDYYITGFDRENLSINIVKSSSKNK
                     YILDYIQNHKNESGIIYVATRKEVENIYNGLSKRNISVSKYHAGLSKNERSKNQEDFI
                     NDNVDIMVATNAFGMGIDKPNIRWVIHYNMPQSIENYYQEIGRAGRDGEKSECVLLFS
                     PGDVHIQKYLIDIGVENPERKLFQHKKLQYMIDLVYSNSCYRKTILSYFGENYIDNCN
                     NCSNCLVEGEIVDKTIDAQKVISCVARMKRSYGVTTIVDVLRGSKNKKILQLGLNTLS
                     TYNIMRDYSSEDLKNFVNTLVSHGFLDLVETLGNGNRGSFPTIRLNEMSMKVLKGEVK
                     VEFKEIVMTKSLEVEDELYNALRELRHSIASEERIAPYMVFGDGTLRAMSSSYPINKE
                     EMLDISGVGEIKYQKYGRDFEAVIKEYVEKNNINKKIDEKNVDSKNVNSDFLEVNTDK
                     VLYEKLLVIREEYATKEKLPAYMILANKALKEISGRYPLDEEQLKDISGIGGVKFEKY
                     GASILAEVNKYVKENNINVIWEKKGKRKLILDGESRKNNEIALDLLNQGKDIQSISQE
                     IEVSLSTIIGYVHDYVKDGHSISFELGLENFYNEDKKKMILEVCEKVGYDNLNNIKRK
                     LPDSIKYENIRAVILDSYLENLKNNIIAE"
     regulatory      8461..8572
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            8714..10015
                     /gene="thiC"
                     /locus_tag="PC494_002966"
     CDS             8714..10015
                     /gene="thiC"
                     /locus_tag="PC494_002966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomethylpyrimidine synthase ThiC"
                     /protein_id="HDF3913449.1"
                     /translation="MNYTTQMDAARKGIITKEMEIVSQKEQVDVNELRELIANGQVVI
                     PANKNHKSLSAEGVGKNLRTKINVNLGISRDCKDIEKELEKVRVAIDMKAEAIMDLSN
                     YGKTREFREKVVEMSPAMIGSVPMYDAVGYLEKELKDITEEEFLNVIRQHAIDGVDFI
                     TIHAGLTRSVCQKIKNHERLTHIVSRGGSLLFAWMELNNKENPIYTNFDKILDICEEY
                     DVTLSLGDACRPGCIKDSTDGVQIQELVVLGELTKRAWERNVQVMIEGPGHMAIDEIE
                     ANVVLEKRLCHGAPFYVLGPLVTDIAPGYDHITSAIGGALACAKGVDFLCYVTPAEHL
                     RLPNLDDMKEGIIAAKIAAHAGDIAKNVKGAREWDNKMSKARADLDWCEMFRLAIDPE
                     KAKRYRDESTPTHEDSCTMCGKMCSMRTVKKILNNEELNLI"
     gene            10069..10263
                     /gene="thiS"
                     /locus_tag="PC494_002967"
     CDS             10069..10263
                     /gene="thiS"
                     /locus_tag="PC494_002967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfur carrier protein ThiS"
                     /protein_id="HDF3913450.1"
                     /translation="MKVNGKEIEFEKDLTVIDLLNKYNLKSDRVVVEVNLEIIEESNY
                     NTYVLKDEDIVELISFIGGG"
     gene            10256..11059
                     /gene="thiF"
                     /locus_tag="PC494_002968"
     CDS             10256..11059
                     /gene="thiF"
                     /locus_tag="PC494_002968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine biosynthesis protein ThiF"
                     /protein_id="HDF3913451.1"
                     /translation="MVKIKIFVNELLTDVEENTTAYKVRDSYNNKCDVLVLNGYPIKT
                     DMTLCENDKLTLIQKGVKPSLDELESLLIARHTPNIHNKLKKGKVAILGLGGLGSNIA
                     ISLARIGVGELLLIDYDVVEPSNLNRQQYFIDDIGKLKTDAMIENIKKINPFIKLNKR
                     DIFLNKNNMDTIKDSDLIIEAFDDASCKAQVCNYVLINLKDKYLIASSGMAGYYDSNI
                     ITTKKIKDRFYICGDFVNEAKFGEGLMAPRVAICANHMANLATQILIDM"
     gene            11122..11892
                     /locus_tag="PC494_002969"
     CDS             11122..11892
                     /locus_tag="PC494_002969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018592874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiazole synthase"
                     /protein_id="HDF3913452.1"
                     /translation="MDKLVLGGHEFNSRLLVGTGKYGSNNILPEVIKESGSEIITMAL
                     RRVDLDNKQENILTYIPKEMTILPNTSGATNAEEAVRIARISRKMGCGDFIKIEVISD
                     TRYLLPDNEETIKATKILADEGFIVLPYMTPDLYAGRRLIEANAAAVMPLGAPIGSNR
                     GLQMKEMIRIMIDELDIPIIVDAGIGKPSQAMEAMEMGADAVLVNTAIASAGDPVQMA
                     RAFKLAVEGGREAYIAKTGNVSEFANASSPLTGFLGNL"
     gene            11909..13012
                     /gene="thiH"
                     /locus_tag="PC494_002970"
     CDS             11909..13012
                     /gene="thiH"
                     /locus_tag="PC494_002970"
                     /EC_number="4.1.99.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-iminoacetate synthase ThiH"
                     /protein_id="HDF3913453.1"
                     /translation="MSFYDVIEKYRDFDFDGYLNNVTDNDVLRSLSKDKLEDFDILNL
                     LSKTAVKHLEDMAQKAHKLSVQYFGKTVCLYTPMYIANYCVNQCVYCSYNIKSGIKRK
                     KLTMDEIREEGEVISKEGFKHLLVLTGESSFHSSVEYIGEAIEILREKFPSIGIEVYP
                     MEVEEYKYIVDKGVEGLTVYQETYDEEIYKRVHIKGPKSNYKFRLDAPERGAKAGMRT
                     LSIGALLGLNDFRKETFFTILHGKYLKTKYPHIELSYSTPRMRPFKGCFEELVDISDT
                     DLVQAMVCMRLFDPHAAINISTRENLEMRSHIIPLGVTKLSAGVSTDVGGHSQDEHDT
                     AQFKINDESTVKDVEKMLNSIGYQHVFKDWERF"
     gene            13013..13702
                     /locus_tag="PC494_002971"
     CDS             13013..13702
                     /locus_tag="PC494_002971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HDF3913454.1"
                     /translation="MYLITNRKLCSEERYLEVIKESILSGVENIIIREKDLEYQELRK
                     LYMKIKTKINCIDFQEQISDESLKTNINQKEFRNKFKVNFIINSNIEFFEKVDCQGIH
                     LPFKLFLNLIENKYNFNENKILGLSLHKVEEVDYLEKLIRNQNIKIDYITLSHIYETK
                     CKEGLNPKGIELLKEAKKITDIKIIALGGILPSNVKETLKYCDDFAIMSTIMRSKDIK
                     KTISNYNEKLN"
     gene            13890..15284
                     /gene="yfcC"
                     /locus_tag="PC494_002972"
     CDS             13890..15284
                     /gene="yfcC"
                     /locus_tag="PC494_002972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative basic amino acid antiporter YfcC"
                     /protein_id="HDF3913455.1"
                     /translation="MTDSKKKRFIIPHTFTIIFLLIVLMAILTWIVPSGEFSREDVEG
                     RMVVVPGTYQSVESNPQGFADVFKAPIEGFIDSAEVVGFVLIVGGAFGIVNRTGAIEA
                     GIASVISKFKGKELLIIPISMILFGLGGTTFGMAEETLPFYMIFVPLMTSLGYDSLTA
                     IAIVFIGAAAGAAASTINPFSVGIAQALAQLAPGSGVTYRVVIFIAYILISIAFVMYY
                     AKKVKENPESSIVYEIDKNNKSILNQTSTEIKEFTFKEVSVLAIFGIGMAIMIWGVLS
                     QGWYIPEISMCFAAIGVLSGLVGRLSQIEISESFIDGAKDLASAALAIALARGIVIIA
                     QNGFIIDTILNSAAAFLGGLPKVIFVYLSFFLEAALAFLIPSSSGLASLTVPVLAPLG
                     DLVNISAQVIVTAYQFGVGLTNFITPTSGVLMGALAVAHIPFSKWVRFIMPILLILTA
                     VSLVFLTIGIYIGF"
BASE COUNT         5731 a         1837 c         2627 g         5267 t
ORIGIN      
        1 aaaaaaaggt ttgatttgaa tataaaactg caatatatta aaaaaattat tcattttaaa
       61 ccttgtaatt tgattttata aatattataa ttaaattaat gaatttttaa caaggaatta
      121 ttcatttttt tgattttaag atttattgag aaaacaaaac taaatagggg ggtaattaat
      181 ataatggatt ttttcaatgg tattttaacg agtattaaca atgcagtagt atatgtaaac
      241 aattacttat ggtcgtatat cttaattata atgttagttg taattggtat ttactttact
      301 attaaaacaa attttgtaca attcagatat tttatagaaa tgtttagact tctgggtgat
      361 ggtacagcga ataaaaatgc aaaaaaggaa ggaaaaatct cttcatttca agcattttgt
      421 ataagtacat cttcaagagt tggaactgga aatatagctg gaatagcaat tgcagtggta
      481 gcaggaggac ctggtgctgt attttggatg tggcttatag cattaattgg ttctgcatca
      541 agctttgttg agagtacatt agctcagatt tacaaagtga aagatggtca agcttttaga
      601 ggtggaccag cgtattatat ggaacaaggt ctaaataaaa aatggatggg tattttattc
      661 tcaatactta taactatatg ttatggtttt gtatttaatg cagttcaagc aaatactgtt
      721 tcacttgcat ttaataatgc atttggaata agtaaaatgg ctatgggaat aggtcttgga
      781 attttaactg caatagttat ttttggtgga gtgcatagag ttgcaaaagt ttctgaaata
      841 atagttcctg tatttgcagg attatatata ttagttgctt tggctatagt tgtaatgaat
      901 ataacagaga taccaagtgt tatagcattg atagttgaaa gtgcatttga ttttaaagga
      961 atggcgattg gtacatttat gggagttgta atgactggag tgaagagagg tctattttct
     1021 aatgaagcag gtatgggtag tgctcctaat gctgctgcaa cagcacatgt aactcatcct
     1081 gtaaaacaag gtttaattca atctttaggt gtttttacag atactataat aatatgtagt
     1141 tgtacagcat tcatggtatt attatattca ggttatagta gtagtggagc aactggaatt
     1201 gaattagctc aagaagcttt aactcatcat ataggaccag ttggaaatat atttatagca
     1261 gtttgtatat tcttgtttgc atttagttct atagttggta attactatta tggtgaatca
     1321 aatatggagt ttatgagtgg aagtaagact aaacttaatg tatttagagt ttttgttgta
     1381 ggtatggttt tatttggttc acttactcaa gtggatgtag tttggaatct tgcagactta
     1441 tttatggcat tgatggcgat aataaactta atagcaatag cacttttagg aaaatatgca
     1501 tttattgctt taaaagatta tacaagtcaa aaaaaatcag gaataaaaga ccctgtgttt
     1561 attgcagatg aaatagaagg cctagaaaag gtatcagagt ggcataggga attatctgag
     1621 gaacatttag gataaaaaat agtataaaat tataaaacca ttttgaaaga ctagagtatg
     1681 tatatacttt atatgaatat aatattgaat taatttatat tactggaatt tttaattcca
     1741 gtaatatttt tttattatat aatttagctt tattaaaagt ttttattatt aaaaatagct
     1801 tatttatcgt aaagtgaatg atattgggtt ttaattatta tgaatgttag tatttaattt
     1861 aaagacttaa ataaatttgc catttctagc gcattcatag cacaatcata acctttattt
     1921 ccagcttttg tacctgctct ttcaatagct tgttcaatat tttctgtagt tacgattcca
     1981 aatataacag gtaattcact gtctaaagat actttggcta tccctttaga gacttcacta
     2041 catacataat cataatgaga agtagcccct cttataacac agcctaaaca gattatagca
     2101 tcatacttac cacttttagc cattttttga gcaacaagag gaatctcaaa agctccaggt
     2161 acccaaacta tttctatatt ttctggagaa acgtcatgtc ttaaaagaca gtcttcagct
     2221 cctgataaaa gttttgatgt tataaattca ttaaaacgag aatttattat acctattttt
     2281 aaatcttttc caataagttt tccttcatat atcattttta cttcctccaa ttttatttat
     2341 gttatagatt tatatttata aatatcttta atttaattat aaaaaactac ttagtagaaa
     2401 aatatcatca tataatcatt tatataatat ctaaaagatg tcccatttta tcttttttag
     2461 tttttaaata tagcttatta aagtcattaa tttcttcatt aatagggatt ctattttcga
     2521 tttttattcc atatttctct aattgattta ttttatctgg gttattactt aaaagattta
     2581 tactttttat gtttaaattt tttaatattt gagcagccat atagaaatct ctcatatctt
     2641 cttcaaatcc aagcattaaa tttgcttcaa cagtatcgta accttcttct tgaagtttat
     2701 aagccttaat tttatttaaa agaccaatac ctctaccttc ttgcttcata taaattaaaa
     2761 ctccacttcc attttccaca attttcttca tagaagattc tagctgtaat ccacaatcac
     2821 attttagaga gtggaacaca tctcctgtta aacattcaga atgaagtcta actagagtat
     2881 tttctatatt tatatttcca taagtaaggg caatgtgttc ttcatttgaa taagtatctc
     2941 tatatcctat gatttcaaaa tttccatatt ttgtcggaag gaaagcacta gatacttttt
     3001 ctatagtagt ttcatttatt ttgcggtatt ctataaggtc ttttatagtg atgattttta
     3061 aattatgctt ttctttgaaa atcattaaat catcaactct tgccattgta ccatcatctt
     3121 tcattatttc acagataaga ccaatctctt taaaacctgc aagtctagca aggtctactg
     3181 aggcttctgt atgtccatcc ctgacaagaa ccccaccagt ttttgctatt aaaggaaaga
     3241 tgtgaccagg cgttttgaaa tctttacttg tagaattttc atcacagaat aattttacag
     3301 tttcagctct ttcatatgca gatataccag ttagagtatc tgctccatct atagtaacag
     3361 taaaggctgt ttgaaatgta tctgtatttt ctctaaccat aagaggtata ttaagacttt
     3421 taaatttttt ttcagtggca ggtagacaaa ttagacctct accatatgta gccataaaat
     3481 ttattgattc aggagtagcc atttcagctg ccatcaataa atctccttca ttctctctac
     3541 tttcatcatc aaccacgatt accattttcc cattttttat atcttcaata gcttcttcaa
     3601 tagtattaaa catgtaattc actcctttat tatttttaaa aaccattttt aaataaaaaa
     3661 tctttatcta tatttgattt atggttatta ctattagaat ttaattcctt gtagttatta
     3721 gccataaaat tattaacata ctttccaatt acatcgcttt ctaaattaac gaaatctcca
     3781 acattctttg tcaagagaat agtgttaatt ttagtatgag gtataataga aaccttaaat
     3841 atttcatcat ctaaatatga tatagttaaa cttacaccat caatagcaac agaacctttg
     3901 agtatcattg aggataaaag ttttttatca ggtcgtatac ttactaaaac tgcattttca
     3961 tctttttcaa atttgcagat agttccttta ccatcaacat gacctgttac tatatgacca
     4021 ccaaatcttg aagaaagact catagctctt tcaagattta ccttgtcatt tgcatttaat
     4081 aaacctaaat ttgtggaacg aattgtctcc atcataacat cggctgtaaa ttcatttttt
     4141 ccgaggtttg aaacagttag acaaactcca tttacggcta tactatctcc aagatttgtg
     4201 ccatctaata ttttatttga tagtatggtt acttttccac tcttaccatt agcagtaatt
     4261 tttctaagta ttccaacttc ttctactatg ccagtaaaca tcctaacctc ctatatgaat
     4321 gtattaacaa aaatttaatt taaaacatct gattctataa gaatatcgcc atctatcaaa
     4381 gttacattat tgattgttaa ctgtgttgaa tctgacaaat gatttattcc ttctccagaa
     4441 acgaatgtag gtgcatcttt accacctata atcttgggtg atagaaataa tttgacctta
     4501 tcaactaact tatttctaaa gagactgtca ttgagagtag caccaccttc aactagaaca
     4561 gaatcaatgt ttaactctcc taatttatac attacaaact ccaaatctac taagttgttt
     4621 tttgaaggag aaattattgt ttcaacatta ttttctttta acatagataa ttttatactt
     4681 tctttgcaac atgtgaaaac tatagtttta ctggttttat ctttaaccaa attactatta
     4741 agtggcaact ttaggtgtgt atctattact attcttgtag gatgagacac tttttcttga
     4801 ttgagcctac aagttagtaa aggattatcg ttcaaaactg tatttatgcc aaccattata
     4861 ctttggtatt tatttctgta tttatgagtt agataccttg atgattcatt agatatccat
     4921 tttgattcta gtgattttgt agcaatttta ccatctagac ttactgctga ttttacaata
     4981 caaagaggtc ttttgttttt tatatgataa aaaaatgcct catttaaatc tcttgcttca
     5041 tcttctaata ttcccacagt aacatcaata ttgttatctt ttaatttttt tactccatta
     5101 ccacaaacaa gtggatttgg gtctaatgta gatattacaa ctctcttaat cttattttgt
     5161 ataattttat ctacacaagg aggcgttttc ccataatgag aacatggttc taagtttaca
     5221 taaagagtag agtcttttag actttgttta gcactgttta tagcatttac ttcagcatga
     5281 ttagagccaa atttctcatg atatcctttg cctattatat tactagcttt aacaattaca
     5341 cacccaacta atggatttgg atttacaaag ccttctccat ttttagccaa ttcaatagct
     5401 tttttcatat aataaatatc tttttctttt tgattcacaa aattcacaat atgtacacct
     5461 cctgtttaat tggataattt ttaaacaaaa aaccctgaga attaactcag ggtttagaat
     5521 aatctacaat aaatgtttaa taaatgtaga acaaaattgc tctacaaaaa cactcattaa
     5581 atatcttctt ccatccagac tttactgtcg gctttggaat ttaaccaaat caaccaagtt
     5641 ttaccttggc tcgcgggcta taccgccgat tgggaatttc accctacccc gaagattaag
     5701 tattaaattt atatttagaa tgtatcataa attattttac tttgcaaact atttttttaa
     5761 aaaatatatg ttaatatata atatagaatg tctataaact ttgaaatacc acgattgtga
     5821 atataaaaat aaaaatttga acataatcag gaaagaagtc taattaattt aaattaggag
     5881 agtaatatat gaataaaaaa cttttagaaa tactatcaaa atactatgga tatacaagtt
     5941 ttagaaaagg tcaagaatct ataataaact ctatcttaag cgaaaaagat gtgttagcta
     6001 ttatgccaac aggaggggga aaatcaatat gttatcaaat tccagctttg attttagatg
     6061 gaatgacaat agtaatttct ccacttatat cacttatgaa agaccaagta gatgccttaa
     6121 agactatggg aattagtgct gcttttataa atagttcatt aagtagcaaa gaatttaatg
     6181 aaatattaaa taatattaga aaaaataatt ataaaatact ctatattgct ccagagagat
     6241 tagatgcaca agagtttatt gagctaataa ataataacaa tgtaagtcaa gttgcgatag
     6301 atgaagcaca ttgtgtatct caatgggggc atgattttag gttgagttat agaaggattt
     6361 ctgattttat aaaaaatttg cctaaaagac ctatagttac agcatttact gcaacagctt
     6421 cagaagaggt aagaactgat ataataaatt tactgtgttt agaaaatcca gattattata
     6481 taactggatt tgatagagag aatttatcaa taaatatagt aaaatcatct agtaaaaata
     6541 agtatatttt agattatatt caaaatcata aaaatgagtc tggaattata tatgttgcaa
     6601 ctagaaagga agttgaaaat atatataatg gtttatctaa gagaaatata tctgtgtcaa
     6661 aatatcatgc aggtttatct aaaaatgaaa gaagtaaaaa tcaagaagat tttataaatg
     6721 ataatgtgga tataatggta gcaacaaatg catttggaat gggtattgat aaacctaata
     6781 taagatgggt tatacattac aatatgcctc aaagtataga aaactactat caagaaatag
     6841 gtagagctgg tagggatgga gaaaaaagtg agtgtgtact tttattttct ccaggagatg
     6901 tacatataca aaaatattta attgatattg gagttgaaaa tcctgaaaga aaattatttc
     6961 agcataagaa gcttcaatac atgattgact tagtttacag taattcatgc tatagaaaga
     7021 caatattgag ttattttgga gaaaattata tagacaattg caataattgt agcaattgtt
     7081 tagtagaggg tgaaatagta gataaaacta tagatgcaca aaaagtcatt tcatgtgtag
     7141 ctagaatgaa aagaagttat ggtgttacta ctattgtaga tgtgcttaga ggttctaaga
     7201 ataaaaagat tttacagctt ggattaaata ctttgtctac atataacatt atgagagatt
     7261 attctagtga agacttaaag aattttgtaa atacattggt ttctcatggt tttttagatt
     7321 tagttgagac tctaggcaat ggaaatagag gtagttttcc tactataaga ttaaatgaga
     7381 tgtctatgaa agttttaaaa ggtgaagtga aagtagagtt taaagaaatt gttatgacaa
     7441 aatcattgga agtagaggat gagttatata atgctttaag agaacttaga cattcaattg
     7501 caagtgaaga aaggatagct ccatatatgg tatttggaga tggtacactt agagccatgt
     7561 ctagtagtta tccaattaat aaagaagaaa tgctagatat ctctggagta ggagaaatta
     7621 aatatcaaaa atatggtaga gattttgaag cagtaattaa agaatatgtc gaaaaaaata
     7681 atataaataa aaaaatagat gaaaaaaatg tcgattcaaa gaacgttaat agtgatttct
     7741 tagaggttaa tacagataaa gttttatatg aaaaactgtt agtcattaga gaagaatatg
     7801 caacaaagga aaaattacct gcatatatga ttttagccaa taaggctttg aaagaaataa
     7861 gtggaagata tccacttgat gaagaacaat taaaagatat ttctggcata ggtggagtaa
     7921 aatttgaaaa atatggagct agtattttgg cagaggttaa taaatatgta aaagaaaata
     7981 atattaatgt tatttgggag aaaaagggca aaaggaagtt aatattagat ggagaaagta
     8041 gaaaaaataa tgaaatagca ttagatttgc taaatcaagg aaaagatata caaagtatca
     8101 gtcaagaaat agaagtttca ctgtcaacca ttattggata tgtgcatgac tatgtaaagg
     8161 atggacatag tatatcattt gaattaggac tagaaaattt ttataatgaa gataaaaaga
     8221 agatgatttt agaagtttgc gaaaaagttg gctatgataa tttaaataac ataaaaagaa
     8281 aacttccaga ttcaataaag tatgaaaata taagagctgt gatacttgac tcttatcttg
     8341 aaaacttaaa aaataatatt atagcagagt aatttttaac ttaataaaaa ataaaatttg
     8401 tattattgtg ttgaactaat aattttgctg tgttatactg aatttgtaaa aataatgaaa
     8461 aattagagct aggggcgcta gaattggcta gctgagagat aaagccgtaa cttacaaacc
     8521 ctaataacct gatcaagata atgcttgcga agggaagctt tttaatataa ttttattata
     8581 taaataggca aattattcaa tgttaggaga aatttgtcta agtgtatata cgattataag
     8641 agtgctttcc aaacgaggaa aagcactttt tttattttca aaaactataa ctttaatctt
     8701 ggaggattgt aatatgaact atacaacaca aatggatgct gctagaaaag gcataataac
     8761 taaagaaatg gaaatcgttt ctcaaaaaga acaggtagat gtaaatgaat taagagaatt
     8821 aatagcaaat ggacaagttg ttataccagc taataaaaat cataaatctt taagtgcaga
     8881 aggtgtaggt aaaaatttaa gaacaaaaat aaatgtaaat ctaggaattt caagagattg
     8941 taaggatata gaaaaagaac ttgaaaaagt tagagtagca atagacatga aagctgaagc
     9001 tataatggat ttaagtaatt atggcaaaac tagagaattt agagaaaagg ttgttgaaat
     9061 gtcacctgca atgataggtt cagtacctat gtatgatgca gtaggatatt tggaaaaaga
     9121 attaaaagat ataacagaag aagagttttt aaatgtaata agacaacatg ctattgatgg
     9181 agtagacttt attactatac atgcaggtct tacaagaagt gtttgccaaa aaataaaaaa
     9241 tcatgagaga ttgactcata tagtatctcg tggaggttct ttattgtttg catggatgga
     9301 attaaataat aaggaaaatc ctatttatac taattttgat aaaatattgg atatatgtga
     9361 agaatatgat gttacattga gtttaggaga tgcttgtaga ccaggttgta taaaagattc
     9421 tactgatggt gttcaaattc aagaacttgt agtattaggt gaacttacta aaagagcatg
     9481 ggaaagaaat gtacaagtaa tgatagaagg tcctggacac atggctattg atgaaataga
     9541 agcaaatgta gtattagaaa agagattatg ccatggagca cctttttatg ttcttggacc
     9601 attggttaca gatatagcac caggttatga ccatataaca agtgcaatag gaggagcttt
     9661 agcatgtgcc aaaggagtag attttttatg ttatgtaact ccagcagaac atttaagatt
     9721 gcctaattta gatgatatga aagagggtat aatagctgca aagatagctg ctcatgcagg
     9781 agatatagct aaaaatgtta aaggtgctcg tgaatgggat aataagatga gtaaagctag
     9841 agctgattta gactggtgtg agatgtttag acttgcaata gaccctgaaa aagctaagag
     9901 atacagagat gaatcaactc ctactcatga ggatagttgt actatgtgtg gaaaaatgtg
     9961 ctcaatgaga acagttaaga aaatattaaa caatgaggaa cttaatctaa tataattttt
    10021 ggctagtatg actggaataa aaataagctg aaaagaggag gtgatttagt gaaggttaat
    10081 gggaaggaaa ttgaatttga aaaagatttg actgttatag atttattaaa taaatataat
    10141 ttaaaaagtg atagagttgt agttgaagtg aatttagaga taattgaaga atctaactac
    10201 aatacatatg tattaaaaga cgaggacatt gtagagctta ttagctttat tggaggtggt
    10261 taaaataaaa atatttgtaa atgaattatt aacagatgtt gaggaaaata caactgctta
    10321 taaagttaga gatagctata acaataaatg tgatgtattg gtgttaaatg gatatccaat
    10381 taaaacagat atgacccttt gtgaaaatga taaattaaca cttatacaaa aaggagttaa
    10441 gccatcactt gatgaattgg aaagcttgtt gattgctaga catactccaa atatacataa
    10501 taaattaaaa aaagggaaag ttgctatatt gggattgggg ggacttggtt ccaatatagc
    10561 tatctcttta gctagaatag gagtgggaga acttttactt atagattatg atgttgtaga
    10621 accatctaat ttaaatagac agcagtattt tatagatgat ataggaaaac taaaaactga
    10681 tgccatgata gaaaatataa aaaaaataaa tccatttata aaattaaata aacgagatat
    10741 ttttttaaac aagaacaata tggatactat taaggattca gatttaataa ttgaggcctt
    10801 tgatgatgct tcatgtaaag cacaggtatg taattatgta ttaataaatt taaaagataa
    10861 atatttaata gcatcatctg gtatggcagg ttactatgat tcaaatataa taactactaa
    10921 gaagataaaa gacaggtttt atatatgtgg ggattttgtg aatgaagcta aatttggtga
    10981 agggcttatg gctccaaggg ttgccatctg cgcaaatcat atggcaaatt tggcaacgca
    11041 aatacttata gatatgtaaa tattaaaatt agatataaaa aagattgaat attaaaaaaa
    11101 tttaacgtgg agggaaataa tatggataaa ttggtacttg gtggacatga atttaatagc
    11161 agattattgg ttggaacagg taaatatggt tcaaataata tattgcctga ggtaataaaa
    11221 gaaagtggaa gtgaaataat aacaatggca cttagaagag tggatttaga caataaacaa
    11281 gaaaacatat taacgtatat tccaaaagag atgacaatac ttccaaatac atcaggagct
    11341 actaatgcag aagaagctgt aagaatagct agaatatcta gaaaaatggg atgtggagat
    11401 tttataaaaa tagaagtaat atcagatact agatatttac ttcctgataa tgaagaaact
    11461 ataaaagcta caaagatact tgctgatgag gggtttatag ttcttccata tatgacacca
    11521 gacctttatg ctggaagaag acttatagaa gctaatgcag cggcagttat gccacttgga
    11581 gctccaattg gttcaaatag aggtcttcaa atgaaagaaa tgataagaat aatgatagat
    11641 gagttggata taccaataat agtagatgca ggtattggaa aaccatctca agctatggag
    11701 gctatggaaa tgggagctga tgcagtactt gtcaacactg ctatagcttc agcaggagac
    11761 cctgtacaaa tggctagagc atttaaatta gctgtagaag gtggaagaga agcatatatt
    11821 gcaaaaacag gaaatgtgtc agaatttgca aatgcatctt ctcctttaac aggtttttta
    11881 ggcaatttat agaaagtggt gattggtgat gagtttttat gatgtaatag aaaaatatag
    11941 ggattttgat tttgatggat atttaaataa tgttactgat aatgatgttt taagaagttt
    12001 atcaaaagac aagcttgaag attttgatat attaaatttg ctttctaaaa ctgcagtaaa
    12061 acatttagaa gatatggcac aaaaagcaca taaattaagt gttcaatact ttggtaaaac
    12121 agtatgttta tatacaccaa tgtatatagc aaattattgt gttaatcaat gtgtttattg
    12181 tagctataat ataaagagtg gaataaaaag aaaaaaatta actatggatg aaattagaga
    12241 agagggagaa gtaatttcaa aagaaggttt caaacatcta cttgttttga ctggagaaag
    12301 tagttttcac tcaagtgtag aatatatagg tgaggctata gaaatattaa gagagaaatt
    12361 tccctctata ggtatagaag tttatccaat ggaagtagaa gaatataagt acattgtaga
    12421 taaaggtgtt gaaggattaa cagtatatca agaaacttat gacgaggaaa tatataagag
    12481 agtacatata aaaggcccaa aatcaaatta taaatttaga ctagatgctc ctgaaagagg
    12541 ggcaaaagca ggtatgagga ctttatcaat aggtgcactt ttagggctaa atgattttag
    12601 aaaagaaact ttttttacaa tattgcatgg gaaatactta aaaacgaaat atcctcatat
    12661 tgagctttca tattcaacac caagaatgag accttttaaa gggtgttttg aggaattggt
    12721 agatataagt gatactgatt tagttcaagc tatggtatgt atgagattat ttgaccctca
    12781 tgcagctata aatatatcca ctagagaaaa tttagaaatg agaagtcata taataccttt
    12841 aggagtaact aaattgagtg caggtgtatc tactgatgta ggaggtcatt ctcaagatga
    12901 acatgatact gctcaattta agataaatga tgaaagtact gttaaagatg tggagaaaat
    12961 gctaaactca attggttatc agcatgtgtt taaagattgg gaaagatttt aaatgtatct
    13021 gataacaaac agaaaattat gtagtgagga acgatattta gaagttatta aagagtctat
    13081 attgagtggt gtagaaaata taataataag agaaaaggat ttagaatatc aagagctaag
    13141 aaaattatat atgaaaataa aaactaaaat caattgtata gattttcaag agcaaatatc
    13201 agatgaaagt ttgaaaacta atataaatca aaaagagttt agaaataaat tcaaggttaa
    13261 ttttataata aatagtaaca ttgaattttt tgaaaaagtg gattgtcaag gtatccatct
    13321 tccttttaaa ttattcttga atttaattga aaataagtat aattttaatg aaaataaaat
    13381 actaggatta tctttacata aagtagagga agtagattat ttagaaaaat taataagaaa
    13441 tcaaaatata aaaatagatt acataacatt atcacatata tatgaaacta aatgtaaaga
    13501 aggattaaat ccaaaaggaa ttgagctttt aaaagaagct aaaaagatta ctgatattaa
    13561 aataattgca cttgggggaa ttttaccatc taatgtcaag gaaacattaa aatactgtga
    13621 tgattttgct ataatgtcaa ctataatgag gtctaaagat attaaaaaaa ccatatcaaa
    13681 ttataatgaa aagttgaatt agtaaatata gtatattgaa tttttaactt aaataaaaat
    13741 aaaaaagtta tcttttaaat tttaaaaggt agctttttta ttttatatct ttgctaataa
    13801 aaaattgtaa aaagggaaaa ctttagtcag agagattaaa caatatccta gaaagattta
    13861 aaatttagta aagtatggag gacattataa tgactgacag taaaaagaaa cgatttatta
    13921 taccacacac ttttacaata atatttttac taatagtctt gatggcaata ttgacttgga
    13981 tagtaccaag tggtgaattt agtagagaag atgtagaagg tagaatggta gttgtaccag
    14041 ggacttatca aagtgtagaa agtaatcctc aaggatttgc agatgttttt aaagcaccaa
    14101 tagaaggctt tatcgattca gctgaagttg taggttttgt tttaatagtt ggaggtgctt
    14161 ttggtattgt aaataggact ggagctatag aagcaggaat agcttcggtt atctctaagt
    14221 ttaagggaaa agaacttctt ataattccaa tatcaatgat tttatttgga cttggaggta
    14281 caacatttgg gatggcagaa gagacattac cattttatat gatatttgtt ccactcatga
    14341 catccttggg atatgattct ctaacagcaa tagcaattgt atttatagga gcagcagcag
    14401 gagcagccgc ttcaacaata aatccatttt cagttggtat tgcacaggca ctagctcaac
    14461 ttgctcctgg ttcaggagta acttacagag tagttatttt tatagcatat atactaataa
    14521 gtatagcatt tgttatgtac tatgctaaga aggtaaagga aaatcctgaa agttcaatag
    14581 tatatgaaat agataaaaat aataaatcaa tacttaatca aacttcaaca gaaataaaag
    14641 aatttacttt taaagaagta tctgttcttg ctatatttgg aatagggatg gcaataatga
    14701 tttggggtgt tttaagtcaa ggatggtaca ttccagaaat atcaatgtgt tttgctgcaa
    14761 taggtgtgct ttctggattg gttggtagat tatctcaaat tgaaatctca gaaagtttta
    14821 tagatggagc aaaagattta gcatctgcag ctcttgctat agctttggct cgtggaatcg
    14881 taataattgc tcaaaatgga tttataatag atactatatt aaattccgca gcagcctttc
    14941 taggtgggct tccaaaggtt atatttgtat atttatcatt tttcttggaa gctgcattgg
    15001 catttttaat tccatcatct tcaggtcttg cttcacttac agtacctgta cttgctcctc
    15061 ttggtgattt ggttaatata tcggctcaag tgatagtaac cgcttatcaa tttggtgtgg
    15121 gtcttacaaa ctttataact ccaacttcag gagtactgat gggagcactt gcagtagccc
    15181 atattccatt ttcaaaatgg gtaagattta taatgcctat cttgttgatt ttgacagctg
    15241 tatctctagt ctttttaaca ataggtattt atatagggtt ttaattaagt gtagttttat
    15301 ttaagatatt tagtaatggt ataaaatgat aatatgtttt caataaattg ccactaattt
    15361 aattagtggt aatttgtttt ttgtatttaa aaataaatgt atttacttgt attttgaatt
    15421 aatatctact tagacattgt tttaattgtt atatttttat tt
//
LOCUS       DAMKNB010000086        15313 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.091, whole genome shotgun sequence.
ACCESSION   DAMKNB010000086 DAMKNB010000000
VERSION     DAMKNB010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 15313)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15313)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15313
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.091"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            complement(92..424)
                     /locus_tag="PC494_002973"
     CDS             complement(92..424)
                     /locus_tag="PC494_002973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HDF3913456.1"
                     /translation="MNTREMKEYRVFYNKKLSETDEFFRVFGSLDDKTYSEGAISKKN
                     KELMGLAISILSRCDECICYHIEGCINSGASKDEIIEAIKIGVIGGGSITYPNARFAI
                     KILEEFNI"
     gene            complement(668..1309)
                     /locus_tag="PC494_002974"
     CDS             complement(668..1309)
                     /locus_tag="PC494_002974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SdpI family protein"
                     /protein_id="HDF3913457.1"
                     /translation="MKKAINKQFILSTLICFIPFIVSIYFYNRLPNEVAIHFDNYGNP
                     DNYAPKVIAAFGVPLLMLCIHLYTWFRLENEPKKANFSNVIQNLSKWGVAILSVIIQI
                     MMVLYSTGVSLESNFYTGLILGIIVILFGNYLPKCKRNYSVGIILPWTLNDEDNWNKT
                     HHLAGWIWLIGGILLIINAFINIPFYNIFVIFVIVILPFIYSYLMYKISGKNN"
     gene            complement(1290..1583)
                     /locus_tag="PC494_002975"
     CDS             complement(1290..1583)
                     /locus_tag="PC494_002975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HDF3913458.1"
                     /translation="MGFPETFKALSDPIRREILVMLRENKMSAGEISEKFNMTNATIS
                     YHLSQLKKAGLIFETKYKNFIFYEINISVFEEVMLWFSQFMEKGEKDNEKSDK"
     gene            1976..2026
                     /locus_tag="PC494_002976"
     CDS             1976..2026
                     /locus_tag="PC494_002976"
                     /inference="COORDINATES: protein motif:HMM:NF024729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3913459.1"
                     /translation="MTEYIYYYNNKRIKKN"
     gene            complement(2552..3304)
                     /locus_tag="PC494_002977"
     CDS             complement(2552..3304)
                     /locus_tag="PC494_002977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TSUP family transporter"
                     /protein_id="HDF3913460.1"
                     /translation="MFSVIFLCIGGFLAAFVDSIAGGGGLISMPVLMAIGVPVHLAIG
                     TNKFAASAGCISSAYRYAKSGKINNDLLKKLVPFTIIGSVLGVRCVLSISEEILNVLV
                     VVMILIVAIYTFISKNLGQEDNFEAVNKKNLRLGMLMALIMGFYDGFFGPGTGTFLTF
                     GFIKIYGYDFLHASANTKILNLTSNITSLLLFMINGQVDYKIAIVFALVMIMGAYVGA
                     KVAIKKGSKMIKPIFLVMALFMVVKLVYQTLV"
     gene            complement(3363..5018)
                     /locus_tag="PC494_002978"
     CDS             complement(3363..5018)
                     /locus_tag="PC494_002978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF3913461.1"
                     /translation="MVDFSESNNEVQKFDWGEVMWIHEPSKTQFNRLSAGIVRFFPGN
                     CQEKHFHLSEEQLLYVIQGEGIQIIDGKKVNIKETSIVYCPPYSEHEIINTGKIDLVI
                     LITYVPHKFSSLRQIPIVFSENNIQELVNVNIIENLANQISNILKLRISVYDLKYKEI
                     FETKKENKFCDICKNIKQCTKKLVKSINNDNFEKVYHCEYGVSSLEIPIVLEENIVGY
                     IECGNFIVYKSIDIDKNLSELSSSSGIDIKYINKIYNEFPLNPKSRLYVLKENLLMMS
                     EFIQEIAKRNFFENQLSIKDEEILKSRKENIRLEEALKKANSRLLEEEYIINPIDMFN
                     NSSKEYPFELELYIEKEIKNMNLEGVYNLIDTNKLRYNDVRDTIQEMIFVLSRTVLRD
                     LEDLKLISYLRNKYNKKISLVNSDEDLWNVLFEFSKECIDKNRAFWRKDKGNLIENIN
                     EYIKKYYKENINLNSISDVFFISPNYLSSIFNERNKVSITEYINLLRIEESKKYLLDR
                     SMSISDICKKVGFNNSSYFSQIFKKFNSITPNEYRKNMLDNKY"
     gene            complement(6291..7370)
                     /locus_tag="PC494_002979"
     CDS             complement(6291..7370)
                     /locus_tag="PC494_002979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDF3913462.1"
                     /translation="MILITLCILVAVFVLAFAGLRLIAPTIIRTSHKIEAPGIDRMEM
                     VEIGGIQQALYIRGQNADNPIILWVHGGPGNSMMPFLHLYQYEWENDFTVVNWDQRNV
                     GKTYFANDPAAVLQTMSAERVLQDVHEVTAYLKQEFNKEKIILIGHSWGTVLGTMAVQ
                     TYPEDYSAYIGIAQTVNMVDNERVGYEKTLEMVKAAGKQKDIKALEAIAPYPPAKYGP
                     SYLAALMTVRTYQSKYGLSINMDLGNIISILATPYYSLRELKNTAIVNQNAIDNQGDV
                     LRFLVEEADIRNYGVDYQVPVYYIMGENDYNSPYLPAKKFFDEIVAPDKQIFFIPDAD
                     HLPFLSKKAEFDCVLLEEIAPKLAK"
     gene            complement(7454..8110)
                     /locus_tag="PC494_002980"
     CDS             complement(7454..8110)
                     /locus_tag="PC494_002980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDF3913463.1"
                     /translation="MTRKNNPKQAIENIITISAKLFAEKGYDKTSMQNIVDASGMSKG
                     GIFHHFSSKEDIFNVVMERRFEQIIETVNQWLGEMHGLTAKEKLRSLVRRHLTDEVIK
                     ESSNMITSAIESPHIILAFTQDNLKKLAPILANVLREGIEDRSIITEFPDECAEVILL
                     LFNFWCDTDVFQGDFPTLRKRFQFLQFLMRQIGVDILEDEIIESINIFYERKPMGQVE
                     "
     gene            8432..8638
                     /locus_tag="PC494_002981"
     CDS             8432..8638
                     /locus_tag="PC494_002981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3913464.1"
                     /translation="MISHAAEICKKYKMPFIIFPTIEKKSIEEWVNIGANMLCLAQDT
                     TFITYVINQLLSFYNEIVPIQKQH"
     gene            complement(8791..9219)
                     /locus_tag="PC494_002982"
     CDS             complement(8791..9219)
                     /locus_tag="PC494_002982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HDF3913465.1"
                     /translation="MSKIYIVYWSGTGNTEKMANFVAEGVKLKGKTPEVLDVSLLKPS
                     DLKEEDKFALGCPSMGAEQLEEGYMEPFVSELESMVSGKQIGLFGSYGWGNCEWMRDW
                     EERMQNAGATIIGGEGITAMEDPNEEAKDECIELGKTLAE"
     gene            complement(9695..10633)
                     /locus_tag="PC494_002983"
     CDS             complement(9695..10633)
                     /locus_tag="PC494_002983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family peptidase"
                     /protein_id="HDF3913466.1"
                     /translation="MNKRMKLIPYEINENLRGAKNKFPYGIKQMNARGMWDEGYTGKN
                     IVVGIIDTGCDISHPLLKGKIIGGANFSDDSNGNKNIYEDFNGHGTHVAGIIAASNYN
                     NEVMGVAPDCKLLIAKALNKDGTGTYQSIINAINFAVNNKVDIISMSLGGNKDDKNLK
                     NAVMQAVKNNISVVCAAGNNGDGDSSTSEYSYPASYAEVIEVGAINENYLVEKFSNSN
                     TTIDLVAPGRNIISTYMDNKLAIMSGTSMSAPYVSGSLALIKEWAREEFERDLDEAEL
                     YAQLIKCTRALGIPRTEQGNGYLYLNLYKYKNNGKR"
     gene            complement(11147..11959)
                     /locus_tag="PC494_002984"
     CDS             complement(11147..11959)
                     /locus_tag="PC494_002984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDF3913467.1"
                     /translation="MFYNAKSCQMMIGSNTVNYIEFGSGKKTLIILPGLGDGLFPLHG
                     KIQAIAFAFRYKQFTKDYKVYVFSRKNQITEKYSTRDMAKDQADIMKKLGIMKAEVMG
                     VSQGGMIAQYLAIDYPELVEKLVLAVTSSKQNDTIQNVICSWINMAKKQNYNDLMIDT
                     AKKSYSERYLKKYQLFIPFLGKVGKPKDFKRFIIQATSCIEHNAFSELNKITCPTLII
                     GGANDKIVGNNASFHLVEKIKKSEIFIYEGLGHATYEEAQDFNERVLEFLNK"
     gene            complement(11982..12614)
                     /locus_tag="PC494_002985"
     CDS             complement(11982..12614)
                     /locus_tag="PC494_002985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDF3913468.1"
                     /translation="MNREEKSKNSKEKIIQSAFSLFSSKGYDSTSTQDIINLSGLSRG
                     AMYHHFKTKEDILRSVTKELYSQMNNFLEHLVADDTLTANEKIIELVVHSANDYTRRK
                     MVHCSWLEKIPFALIEEVRNLNNVVAPNIAKIIKQGVENKEFSCEYPEELAEMLVFSI
                     DILLDPVLFKREYSEVCNRLDFLLFMLKKMDIPLIDEYGIQKFKDLFRQL"
     gene            complement(12958..14613)
                     /gene="ilvD"
                     /locus_tag="PC494_002986"
     CDS             complement(12958..14613)
                     /gene="ilvD"
                     /locus_tag="PC494_002986"
                     /EC_number="4.2.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020457899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxy-acid dehydratase"
                     /protein_id="HDF3913469.1"
                     /translation="MRSDIKKGIEGAPKRALMYGMGLTKEEIERPLIGIVNAQNEVIP
                     GHLHLDEIAEAAKNGVRMSGGLPLEFPAIGVCDGIAMGHVGMNYSLASRELIADSIEA
                     MAMAHGFDALVLIPNCDKIVPGMLMAAARLNIPSIVVSGGPMLPGKKNGKVYDFNSAM
                     EGVGACKDGTVSEEELEALAMNSCPGCGSCSGLFTANSMNCLTEALGMGIPYNGTAAS
                     HSGERKRIAKYAGMYVMELLKNDIKPRDILTIDAFKNAIAVDMAMAGSTNTVLHLPAI
                     AYESGIELNLDFFDEISEKTPCLTKLSPSGKHHIEDLHMAGGIPAIMNELSKINGINL
                     DCKTVTGKTIGENIRNCEIENEEVIHTLKNPYSNQGGLAILKGNLALNGAVVKKSAVA
                     EEMLVHEGPARVFNSEEEAVNAIFGKKINKGDVIVIRYEGPKGGPGMKEMLSPTSAVA
                     GMGLDKYVALLTDGRFSGATRGASIGHISPEAMEGGLIGLVEEGDIISINIPDKKLEL
                     KVDEVEIENRKLKFKPLEPKIKHGYLSRYAKLVTSANTGAVLK"
     gene            complement(14937..15236)
                     /locus_tag="PC494_002987"
     CDS             complement(14937..15236)
                     /locus_tag="PC494_002987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3913470.1"
                     /translation="MKWIKWYSITCICIFIVVAFYMFIFPNKIETIDTSSAYSFVEKK
                     VPNSAVYQGYKKNPVDGTTTIYYSYDNSTHIVRLSHPEDYSRKINWDKVSNIRFD"
BASE COUNT         5039 a         2730 c         1635 g         5909 t
ORIGIN      
        1 ttaataagaa gtgaacttag aaaataaagc ttaatttcaa agacttaaat agactattat
       61 tattagtcta aataaactac gtctatcaaa attatatatt aaattcttct aaaattttta
      121 ttgcaaatct tgcgtttgga tatgtaatag acccgccacc aattacacct atttttatag
      181 cttctataat ttcatcttta cttgctccag aattaataca accctcaata tgataacaaa
      241 tacactcatc acatcggctt aaaattgaaa tagctagtcc cattaattcc ttattttttt
      301 tacttatagc cccttctgaa taagtcttat catcaagact tccaaatact ctaaaaaact
      361 catctgtttc gcttaatttt ttattgtaaa ataccctata ttctttcatt tctctagtat
      421 tcatcttcta cctcctatgt ttttcttata agaatatcac actgtactta tattttcaat
      481 attaaataca aattttcatt ttatgttcat tagcctaatt tatattattt tttgaaatct
      541 caataagtta tcatataagt aagatttttt cagaactaaa atagaaatct tagtaatttc
      601 tttattacct atctcagttc tgaaatatat tattcttatc caaacattat tatattgatt
      661 aattatatta gttattttta cctgaaattt tatacatcaa ataagaatat ataaatggta
      721 gtattacaat tacaaagatt acaaagatat tataaaaagg aatattaata aatgcattaa
      781 taattaataa tattccacca ataagccaaa tccatccagc taaatggtgt gtcttattcc
      841 aattatcttc atcattaaga gtccatggca aaattattcc tactgagtaa tttcgtttac
      901 atttaggaag atagtttcca aataaaataa ctattattcc taaaattaat cctgtataaa
      961 aattagactc caaactaact cctgttgaat ataaaaccat cattatttgt ataattactg
     1021 aaagtatagc aactccccat tttgataaat tttgtataac atttgaaaaa ttagctttct
     1081 taggctcatt ctcaagtcta aaccatgtat acaaatggat acatagcatt aacaatggta
     1141 caccaaaagc tgctataacc tttggagcat aattatctgg atttccataa ttatcaaaat
     1201 gaattgcaac ttcatttggt aatctattat aaaaatatat tgatacaata aatggtataa
     1261 aacatattaa agtagataaa ataaattgtt tatttatcgc ttttttcatt atctttttct
     1321 cccttctcca taaattgtga aaaccaaagc ataacctctt cgaaaactga aatatttatt
     1381 tcgtagaaaa taaagttctt atactttgtt tcaaatatga gtcctgcctt ttttagttga
     1441 gatagatgat aagaaattgt agcattcgtc atattaaatt tttcactaat ttctcctgct
     1501 gacattttat tctccctcaa cataaccaat atttctcttc ttatagggtc tgaaagagct
     1561 ttgaatgttt ctggaaaccc caacaccatc acctcgctat ttagaatttc atctaaatag
     1621 aatataacat aacatccatt ttatttcaat agctatttag aaatttttct aaatagctat
     1681 ttctaaatag ttattgaaaa ttttcatatt aagattctca atttacttaa gtcgctttta
     1741 tttaatctta ctttatctaa tttttttaac ttaacaaaag tgtattgcac cataattgtt
     1801 aaagcaaaaa cctaatgact gagatactta tatatataac aatactttta attttaaatt
     1861 aaaagtagct aaacccaatt taaaaagtag ttaagtccta tttaaataga aaagaatgaa
     1921 acgagaaata tactgtataa aagtacataa aaacatctac taattagata caactataac
     1981 agaatatatt tattattata ataacaaaag aataaaaaaa aattaattta gcataacctt
     2041 gttaaatata gatttgaata tgaatttaaa gttatgtaaa attaaaaata caggaatgaa
     2101 aattccattc ctgtataaaa tctaactttt gagtctcagt acaatcttat tttgagacaa
     2161 tcttttttgt tttatatttt cttatattta aaatataacg catatcttat gcaacatatt
     2221 catatttttc tttatattct ttcatcgcat cattccaagc gtcttgtact gttacacctc
     2281 ttttattagc aattttttgt gccagttcaa ttatcttcat agctcttctt gatatgttca
     2341 taaacattcc tcctacaaat taccatatat ttcatatata taaatcaagg ttatattttt
     2401 atgatatata atccttctat tgtaagatta cagtttatat gtgtattata tatgaactat
     2461 attagaagat aattagaatt tttataaagc tatatgatta gattaaatat aaaagcttta
     2521 caattactta taaatttaaa aagtctataa gctaaactaa tgtttgatat accaatttta
     2581 cgaccataaa taatgccatt actaaaaata ttggttttat catctttgaa cctttcttta
     2641 tagcaacttt agcacctaca taagctccca ttatcatcac taatgcaaac actatagcaa
     2701 ttttataatc tacttgacca tttatcatga ataataacaa tgaagttata ttacttgtta
     2761 agtttaatat ttttgtattt gcagaagcat gtaaaaaatc atatccatat atttttataa
     2821 atccaaaggt caaaaaagtt cctgtacctg gaccaaaaaa accatcataa aaacccatta
     2881 taagagccat aagcatccct agtcttaaat ttttcttatt aacagcttca aaattatctt
     2941 cttgacctaa atttttagaa ataaaggtgt aaatagccac tattaaaatc ataaccacaa
     3001 ccaaaacatt taatatctct tcacttattg ataatacaca tctcacacct agaacactac
     3061 caataatagt aaatggtact aattttttta aaaggtcgtt attaattttt ccagactttg
     3121 catatctata ggcactactt atacatcctg ctgatgctgc aaatttattt gtaccaatgg
     3181 caagatgtac tggcactcca attgccataa gaacaggcat gcttataagt cctcctcctc
     3241 ctgctataga atctacaaaa gcagctaaaa acccccctat acataaaaaa ataactgaaa
     3301 acataaaatt cctccatcat tctctttcaa tttttcttac aatatatatt atataatctt
     3361 atttaatact tattatccag catattcttt ctatattcat ttggagttat actattaaac
     3421 ttcttaaata tttgtgaaaa ataactactg ttattaaaac ctactttctt acaaatatca
     3481 ctaatactca tgcttctatc taacagatat tttttagatt cttctatcct aagaagattt
     3541 atatactcag ttattgaaac tttatttctt tcattaaaaa tagaactcaa ataatttgga
     3601 cttataaaaa aaacatctga tatactattc aaatttatat tttctttata atattttttt
     3661 atatattcgt ttatattttc aattagattt cctttatctt ttctccaaaa tgctctattc
     3721 ttatcaatac actctttgga aaattcaaat aatacattcc ataaatcttc atcactgttt
     3781 acaagtgata tttttttatt atatttattt cttaaataag atataagttt taaatcctct
     3841 aaatctctaa gcactgttct agacaataca aatatcattt cctgaatagt atctctaaca
     3901 tcattatatc ttaatttgtt tgtatctatt agattataaa caccttctaa attcatattt
     3961 ttaatttctt tttcaatata aagttctaat tcaaagggat attcttttga agaattattg
     4021 aacatatcta tcggattaat aatatactct tcttctaata atctactatt tgctttttta
     4081 agtgcctctt caagtcttat attttctttt ctactcttca atatctcctc atcttttata
     4141 ctaagttgat tttcaaaaaa attcctctta gctatttcct gaataaattc agacatcatt
     4201 aataaatttt cttttaatac atataaccta cttttaggat ttaatggaaa ttcattgtaa
     4261 attttgttta tgtattttat atcaatacca gaactacttg ataattcaga taaattttta
     4321 tctatatcaa tagacttata tactataaaa ttaccacatt ctatatatcc aactatattt
     4381 tcttctaata ctataggtat ctctaaactg gaaacaccat actcacaatg gtacactttt
     4441 tcaaagttat cattatttat gcttttaaca agttttttag tacactgttt tatattttta
     4501 caaatatcgc aaaatttatt ttctttctta gtctcaaata tttctttata ctttaagtca
     4561 tatacagata ttctaagctt caatatatta gatatttgat ttgcaagatt ttcaattatg
     4621 tttacattaa ctaactcctg tatattgttt tcagaaaata ctataggtat ttgtctcaaa
     4681 ctcgaaaatt tatgaggaac ataagtaatt aatattacta aatcaatttt accagtgttt
     4741 ataatttcat gttctgaata tggtgggcaa taaactatag atgtttcctt tatattgacc
     4801 tttttaccat caattatttg tattccttct ccctgaatca catataaaag ctgttcttca
     4861 cttaaatgaa aatgcttttc ttggcagttt cccggaaaaa atcttacaat tccagcacta
     4921 agtctattga attgtgtttt tgatggttcg tgtatccaca taacctctcc ccaatcaaat
     4981 ttttgtactt cattatttga ctcactaaaa tccaccataa actcacctcg tagtttttgt
     5041 ctaaatattt tttcttccct tcttatatta aaataatatc atcatcatta actttcatta
     5101 ctataaaatc atcatactct tttaatactc ctgtaatttt agttgcactt agtttactac
     5161 aattcagttt tttaatatat tgataaattc tataattact tttttatttt gtaaaatcag
     5221 tgttttccca aaataattat atctataaat gaaagtattt ttactgctta catcaatata
     5281 tgttatcata attttccttt ttattgcata tataaataac tgtatataac attgtccaat
     5341 actatataga aatacatcta agaaagaata ttattaaatt gttccaatta gtattatttt
     5401 tcttataaaa ataaaaaaac tgttggattc ttttagaaaa attatttttt acataccttt
     5461 tttgcttaga tagtctatct tctcagctat tttgtatata cactcttcta gttcatgatt
     5521 ttattttaat atcttgctta tattgctgaa ataattgaat tcttttatct atcatattgt
     5581 ctcttatatc ataaacatat tgtttcttat atcacaaaaa tgaaagcatt cttatatctt
     5641 caatatataa acctgctttt tttaatcttg taataaatat aggatactct atattctctt
     5701 cctagaaata actaatacca cttatttttc tattatatag aaagtaataa atctttttct
     5761 taataaaatt caatagtaag tggaataaaa ttttatatga ataagaacat tataaaaata
     5821 ctttatacaa tagtcaataa aagatattag cttcaaatta tgttaaagtt gtattattta
     5881 aagtgaaaaa acaaataaaa aagaaataat agtataagta gaaaaatata cttaaaacaa
     5941 ggcgaagcct ctcttgtatc taaatcaagt agagaattaa atctaaaaaa gaaaataaat
     6001 ataaaagatg actcctgtac attacaagaa tcatcttatg gtttcataat cactccatgg
     6061 tttttaactg tctgatataa aggtctcagt tcactcatag catgaccacc ctttccgatt
     6121 gctgaccccg tcacttatgg acaaaatgtc cataagtgat agtcctctct taaaaccctc
     6181 taaatagata tatctcaagc acctcattga aaccagttgc tggaaacaaa ctgaagcgtt
     6241 ctggaatagt aaaagaaatt gccaccatat ccacgttact gtcctagttg ttactttgct
     6301 aacttcggag caatttcctc taacaatacg cagtcaaatt ctgccttttt gctaagaaat
     6361 ggcagatggt ctgcatctgg tataaaaaaa atctgtttgt ctggcgccac tatttcatca
     6421 aaaaatttct tcgctggaag ataggggcta ttatagtcat tttctcccat gatgtagtat
     6481 acagggacct gatagtcaac tccataattt cttatgtcag cttcttccac taaaaaccgc
     6541 aatacatcac cttgattgtc aatcgcattt tgattgacaa tggccgtatt ttttaactct
     6601 ctcaatgaat aatacggggt tgccagtata ctgattatat tgcccaaatc catatttata
     6661 gaaagcccat acttgctttg gtatgttctt actgtcataa gagctgccaa atagcttgga
     6721 ccatattttg ctggcggata tggtgcaata gcttccagcg ccttgatatc tttttgcttc
     6781 cctgcagctt tcaccatttc aagtgtcttt tcatagccca cgcgctcatt gtccaccata
     6841 ttaacggtct gcgcaatccc aatgtacgcg ctgtaatcct ccggataggt ttgcacagcc
     6901 atagttccca gcactgttcc ccagctatga cctataagga taattttctc cttgttgaac
     6961 tcttgcttca aatatgctgt cacctcatgg acgtcttgca gaacacgctc cgcgctcatg
     7021 gtctgcaaaa ctgctgccgg atcgttcgca aagtatgttt tgcctacgtt tcgctgatcc
     7081 cagttcacca cagtaaaatc attttcccac tcatactggt acagatgtaa aaatggcatc
     7141 attgaattac caggaccccc atgaacccaa aggatgatgg ggttgtctgc gttttgtccc
     7201 cggatatata acgcctgctg tatgccgccg atctccacca tttccatgcg gtcgattcca
     7261 ggagcttcta ttttatggct tgtacgtata atcgtggggg ctatcagacg caaaccggca
     7321 aacgccagaa caaaaacagc aactagtatg caaagtgtga ttaatatcat tttaagtacc
     7381 ttctttcatg aattttttta gccatagata tctcctctaa cattaaaaaa aatatgttgc
     7441 tattttagtt ttgttactct acctgtccca ttggtttcct ttcataaaaa atattaattg
     7501 attctataat ctcatcttcc aggatatcaa ctcctatttg tctcataaga aactgtaaga
     7561 attgaaaccg tttacgaagt gtaggaaagt ccccctgaaa tacatctgta tcacaccaaa
     7621 agttaaagag cagcaaaatt acctctgcgc attcatctgg gaactctgtg atgatgcttc
     7681 tatcctctat gccttctcgt aaaacatttg ctaatattgg tgctagtttt ttcaaattat
     7741 cctgtgtaaa tgccagtatg atatgcggac tttctatagc gcttgtaatc atgttactag
     7801 attcttttat cacctcatcc gttaaatgcc gcctaactaa acttctaagc ttctcttttg
     7861 ctgtaagtcc atgcatttca ccgagccatt gatttactgt ctctattatc tgttcaaagc
     7921 gcctttccat gaccacatta aaaatatctt cttttgaact gaagtgatga aaaattccgc
     7981 cctttgacat tcccgaagca tcaacaatat tttgcatact tgttttgtca tatccttttt
     8041 cagcaaacaa ttttgcagaa atggtaatga tattttcaat agcttgcttt ggattgttct
     8101 ttctagtcat tatataactc cttcttatta aaaaccgact gttggttttt attatataag
     8161 ctattcctac ttctgtcaag caacattatg tttatggcaa aacaataagg tttggtggtt
     8221 agacaggtat taattagact aatgcgactt tcccctagat ggaacccttg gtaaatttgc
     8281 aatctttacc ggctttgatt atatctgtaa gcaaggcagg tatggccaca cctgccctgt
     8341 ttgaccctcg gatattcatt cctatccctt ctctccttag ccattacacc aaaacgccgc
     8401 tcattgtctc caatggcggc gttttaaaga tatgatttct catgctgctg aaatatgcaa
     8461 aaaatataag atgcccttta ttatttttcc tacaatagaa aagaaaagta ttgaagaatg
     8521 ggttaatatt ggagcaaata tgctttgttt ggcacaagat actaccttta tcacttatgt
     8581 tatcaatcaa ttattatctt tttataatga gattgtacca attcaaaaac aacattaaat
     8641 tataaatcta attttatatt aaaagagact aatattttat ctatctctgt taaggatatt
     8701 ttcttatgta tcataatatt agtctctctt attattatat actgctatca tcattagttg
     8761 ctatttatac tatttttata atatacaaat ttattcagct aacgttttgc ctaattctat
     8821 acactcatct tttgcttctt catttgggtc ttccattgct gtaattcctt ctccaccaat
     8881 aattgtagca ccagcatttt gcatacgttc ttcccagtct ctcatccatt cacaatttcc
     8941 ccatccatat gaaccaaata atccaatctg tttacctgat accatagatt ctaattctga
     9001 aacaaatggc tccatatacc cctcttctag ttgctctgct cccatagatg ggcaacctaa
     9061 tgcaaattta tcttcttctt ttaaatcact tggtttcagt aagctcacat ctaaaacttc
     9121 tggtgtctta ccttttaact tcacaccttc agccacaaaa tttgccattt tttcagtatt
     9181 tcctgttcca ctccaataaa caatatatat tttactcatt tttacctcct gtagtatttt
     9241 ttaattaatc aatagttagt tatagctaac taacatctaa aaaacaaaag atttctttat
     9301 ctgaaatctc tttatttttc taaatataga atatcatagt tgattttgaa attcaatgct
     9361 tattgataat atttatcatt tatattttat attcatttta taatatcaaa acactgcatc
     9421 gtatttctaa tctttcatag aaaaatttct aacttatagt acttttgcat ctcttataaa
     9481 tcttttatat gtataagtac atagaaaaac acaccttttc cagatgtgct atctataata
     9541 tcgtatattt atttttcaat tttaactagc taatatgttt ataaatttta tcacttaata
     9601 cctttataca ttgatgtaaa atcttacacc taagtaattt ttattatttg tctcgactct
     9661 atataatata gctattttat catcaaatca aaaattatct tttgccatta ttcttgtatt
     9721 tatagagatt taaatataag tatccatttc cttgttccgt tctaggtatt ccaagcgctc
     9781 tcgtacattt tattaattgt gcatacagtt cagcttcatc taaatctctt tcaaactcct
     9841 ctcttgccca ttctttaatt agtgctaatg agcctgatac gtatggtgca ctcatactgg
     9901 taccactcat aatagcaagt ttattatcca tataagtcga tataatattt cttcctggag
     9961 ctaccaaatc tattgtagta tttgaattac taaacttttc aaccaaatag ttttcattta
    10021 ttgcacctac ttctattacc tcagcataac tggctggata actatactca cttgtactag
    10081 aatcaccatc tccattatta cctgctgcac acactacaga aatattattt tttactgctt
    10141 gcatgacagc attttttaaa ttcttatcat ctttgtttcc accaagagac atagatataa
    10201 tatcaacctt gttatttaca gcaaagttaa tagcattaat tatactttga tatgttccag
    10261 taccatcttt atttaatgct tttgctatta ataatttaca atctggagct actcccataa
    10321 cttcattatt atagttagat gcagctataa tacccgccac atgagttcca tgaccattaa
    10381 aatcctcata tatattttta tttccattac tgtcatcact aaaatttgca ccaccaatta
    10441 tttttccttt taaaagagga tgagatatat cacaacctgt atctattata ccaactacaa
    10501 tatttttacc agtataacct tcatcccaca ttcccctagc attcatttgt tttattccat
    10561 atgggaattt attttttgca cctcttagat tttcatttat ttcatacgga attagtttca
    10621 ttcttttatt catcatatat cctcctaaaa attttattgc ttataaaaat catgaatttt
    10681 attttataat aggtttataa atcaaattaa aacctatatc tacttattta tatttatgat
    10741 atatttttta tttttaggag tcatatttta ttgtatataa aataatattt agataactat
    10801 attaaaaaat acatgtttgc ttatatacaa aacttactaa aatgtcttta atatttttgt
    10861 atacaaacat tatatttttt atataaaaag ctcataaaaa ttttgattat attttcataa
    10921 gttaacaaat gtgggtataa tatgaattta caaaattcct ctgtttgtat aagtgcttta
    10981 ccaatacaac aatatataat cacattgaag ctatatttgt atttatagta gataatgtat
    11041 caaaaattgg ttatgaatag taaaaatacc agttaagcat attttcatgt ttctattttt
    11101 aacattaaat ttccaatctt catatgtata tttttaacaa aggtgtttac ttatttaaaa
    11161 actctaaaac tctttcatta aaatcctgtg cttcttcata tgtagcgtgt cccaatccct
    11221 catagataaa tatttcgctt tttttaattt tttctactaa atgaaaagaa gcattatttc
    11281 caacaatttt atcattagca cctcctataa ttaaggttgg acatgttatt ttatttaatt
    11341 cggaaaaggc attatgttct atgcaagagg tcgcttgaat aataaatcgt ttaaaatcct
    11401 ttggtttacc tacttttcct aaaaaaggaa taaataattg gtattttttt aaatatcttt
    11461 cagaatagga tttctttgct gtgtcaatca ttaaatcatt gtaattctgc ttcttcgcca
    11521 tattaatcca actacaaata acattttgga tagtatcatt ttgctttgaa gaagtaactg
    11581 ccaacacaag tttctcaact aactcaggat aatcaattgc cagatattga gctatcattc
    11641 caccttgaga aacacccatt acttctgctt tcataattcc aagttttttc attatatctg
    11701 cttggtcttt agccatatcc cttgtggaat atttttctgt aatttgattt tttctactaa
    11761 atacataaac cttataatct tttgtaaatt gcttatatct aaaagcaaaa gcaatcgcct
    11821 gtatttttcc atgtaaagga aataaaccat ctcctaatcc tggtaaaata attagtgtct
    11881 tcttaccact accaaattca atataattca ctgtattact tcctatcatc atttgacaac
    11941 tttttgcatt ataaaacata gtctattcct cgcttttcct attataattg tctaaataaa
    12001 tctttaaatt tttgaatacc atactcatca attagaggaa tatccatttt ttttaacatg
    12061 aataataaaa aatccaacct attacatact tcactgtatt cacgtttaaa taatacaggg
    12121 tcaagtaaaa tatcaatact aaaaacgagc atttcagcta attcctctgg atattcacaa
    12181 gaaaattctt tattttcaac accttgttta attatcttag caatattggg tgcaactaca
    12241 ttgttgagat tacgaacttc ctctattaaa gcgaatggga ttttttctaa ccagctacaa
    12301 tgtaccattt ttctacgtgt gtaatcattc gcactatgaa caaccaattc tattattttt
    12361 tcatttgctg taagggtgtc atcagcaaca agatgctcta aaaaattatt catttgtgag
    12421 taaagttctt ttgtgacact tctcagtata tcttctttag ttttaaagtg atgatacatt
    12481 gcacctctag atagaccaga taaattgata atatcttgtg tagatgttga atcatatcct
    12541 ttagacgaaa atagtgaaaa tgctgattgg ataatttttt ctttactatt tttacttttt
    12601 tcttctctat tcatatttcc ctcctaaaaa cagactgtct gtttgttttt cattatacat
    12661 tttaatattt attatgtcaa gaattaactg actttcaatt tcttcatagt ttagatggaa
    12721 cgaaaagcat tccacatcaa acttttaaaa agttgtattc cctcaacaag gtctaaaaga
    12781 tacatctcta tgctgtactc gtattcctta taatagagat gtattgtttt caaagataat
    12841 caagattttg ctgtgttttt catacaaaat aaaaaggata cctcattagt gctataacac
    12901 ctaagatatc caattaatat tttcttaact ttttctaatt tacataaata tagtctacta
    12961 ttttaaaact gctcctgtat ttgctgatgt taccagttta gcatatctac ttaagtatcc
    13021 atgctttatt ttcggttcta aaggtttaaa ttttaatttt ctattttcta tttcaacttc
    13081 atctactttt aactctaatt ttttgtctgg tatgtttata gaaattatat ctccttcttc
    13141 aactaacccg attaaaccac cttccatagc ttctggagaa atatggccta tagatgctcc
    13201 tctagttgct cctgaaaaac gaccatcagt aagaagtgct acatacttat caagtcccat
    13261 tcctgcaact gctgatgtag gagatagcat ttctttcatt cctggaccac cctttggacc
    13321 ttcatatctt ataactataa catcaccttt gtttattttt ttaccaaaaa tagcatttac
    13381 agcttcttct tctgaattaa aaactcttgc tggtccttca tgaactaaca tttcttctgc
    13441 aactgctgac ttttttacaa cagctccatt tagagcaaga tttcctttca atattgcaag
    13501 tccaccttgg ttactatatg gattctttaa tgtatgtatt acttcttcat tttctatttc
    13561 acaatttctt atattttccc ctatagtctt gcctgttacg gttttgcaat ctaaatttat
    13621 tccatttatc tttgaaagtt cgttcattat agctggtatt cctcctgcca tatgtaaatc
    13681 ttcaatatga tgttttccac ttggacttaa ttttgttaaa caaggagttt tttcacttat
    13741 ttcatcaaaa aaatctaagt taagctctat tcctgattca taagctattg caggtaagtg
    13801 aagtactgta tttgtagagc cagccattgc catatccaca gctatagcat ttttaaaagc
    13861 atctattgtt aaaatatctc taggttttat gtcgttctta agtaactcca taacatacat
    13921 acctgcatat tttgctatcc tttttctttc tccagaatgt gacgcagcag taccattata
    13981 tggtataccc atgcctaaag cttctgttaa acaattcatg ctatttgctg tgaaaagacc
    14041 agaacatgaa ccacatccag gacaagagtt catggctaac gcttctaatt cttcttcact
    14101 tactgttcca tctttacatg ctccaacacc ctccattgca gagttaaaat catatacttt
    14161 tccatttttt ttacctggaa gcataggccc tccactcaca acaatacttg gtatattaag
    14221 tcttgcagca gccattaaca tacctggcac tatcttgtca caattaggta taagtaccaa
    14281 agcatcaaaa ccatgtgcca tagccatagc ttctattgaa tctgctatta attctcttga
    14341 agccagggaa taattcattc cgacatgccc catagctata ccatcacata cccctatagc
    14401 aggaaattct aatggcaaac caccactcat tcttactcca ttttttgcag cttctgctat
    14461 ttcatcaaga tgcagatgac caggaatcac ctcattttgt gcatttacta tacctattaa
    14521 tggtctttca atttcttctt tagtaagacc cattccatac attaacgctc tctttggagc
    14581 tccttctatt ccttttttta tatcacttct cataatatta cctctttctt acttttttaa
    14641 attttcataa tattattata atatattttt ctattaatta attacgaaaa ttgtaaaaaa
    14701 atattagcat atactaatga aaatttatta cgatttttta tcaatatctt acacaatcgt
    14761 attatataat attatctttt caatatattt tataaactaa tatattttac aaattgttaa
    14821 gtaatatttt atgatataaa tcagaagagg cacttctata atagaaagtg ctcaactatg
    14881 aataagatta ataatatatt tgccttagat atatagactt ttataaatat taaagattaa
    14941 tcaaatctga tgtttgaaac tttatcccaa ttaatcttcc ttgaatagtc ttctggatgt
    15001 gataatctaa ctatatgagt tgaattatca tagctgtaat aaattgtagt agtaccatca
    15061 actggattct ttttgtatcc ttgatacaca gcactatttg gtactttctt ttcaacaaag
    15121 ctatatgcag atgaagtatc aatagtttct attttattag gaaatataaa catataaaaa
    15181 gctactacta taaaaataca tatgcatgta atactatacc atttaatcca tttcataaaa
    15241 ttcctcctac tttaccaaaa tatactatta ttatttccat atatttataa tatttataca
    15301 tacgataaaa ttt
//
LOCUS       DAMKNB010000087        14152 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.093, whole genome shotgun sequence.
ACCESSION   DAMKNB010000087 DAMKNB010000000
VERSION     DAMKNB010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 14152)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14152)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14152
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.093"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            322..552
                     /locus_tag="PC494_002988"
     CDS             322..552
                     /locus_tag="PC494_002988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3913471.1"
                     /translation="MRLDMDSMLYVLIYMTLLVSIIGSIFYFCKDLLNHKIKYVLIRD
                     IFVNRITYSEERLPKQYIVFQKYDIWRYCSLF"
     gene            609..1259
                     /locus_tag="PC494_002989"
     CDS             609..1259
                     /locus_tag="PC494_002989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HDF3913472.1"
                     /translation="MDFISSILQGLLSILFNFTGDFGISIVLITLIVKLVLMPLSLKQ
                     RFSVKKQQELAEKMEYIKEKYKNDTKELEKQIQVSSVESMKSMLGCLIVLVQMPVVYA
                     LYHVCLDMTKEFTTIIIPWIANLGTFDNLFILPCIYTLIMLASNLVNYIPYLKINSQV
                     KFNKQMAVVTTITSLILTVRTPVAIGLYFITSAIYSLIEDICFRIYFNRKNRIVTK"
     gene            1462..2133
                     /locus_tag="PC494_002990"
     CDS             1462..2133
                     /locus_tag="PC494_002990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF3913473.1"
                     /translation="MAKILVVEDEKRMQNIIVEYMQKGGYTCITADDGVEALTILKSN
                     NIDLMILDIMMPYLDGFSVCRVSREMTNIPIIILTAKGEEEDKLKGYEYGADDYITKP
                     FSPKVLLAKVNALLRRYTTDIPKNSLSLGKIFIMVASRQVYVEDKLIDLTYKEFELLR
                     LFMENPNQVFSREKLLNCIWGYDFEGNTRTVDTHIKTLRKKLGSEGHHIVTLIRSGYK
                     FEVKE"
     gene            2130..3260
                     /locus_tag="PC494_002991"
     CDS             2130..3260
                     /locus_tag="PC494_002991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF3913474.1"
                     /translation="MNSLRKIIEKLKNVDISNWIKQNFGLYSVRKKVFLLSKLSGALI
                     ILFYLVVEEFSINSKFEFWIWFIILVIFIMSIDFLLGKFISEPITSINKSAKSMSQLD
                     FSNPCTVNTNDEFGELSRSLNTMSTNLQQALSDLESANIQLEKDVNKERMLLEQRKEL
                     VDTISHEMKTPLGIIRAYTEGLIDEVDEEKKKNYMNVIIEETDRMNNMIVSLLDLSAL
                     EAGVSKLNPERFDFIEFVETVAGRLLIDIPDANFYFTYDLPEYEVFVVADKMRMEQVV
                     ENLVINAKKHVVYNGNLDLSITCENGLLLFEIYNDGRFIEQDEISKIWSKFYRSVQSQ
                     RTGGSGLGLAIVSQILTMQGLEYGVNNRDRGVEFYFMIPIDE"
     gene            3691..4536
                     /locus_tag="PC494_002992"
     CDS             3691..4536
                     /locus_tag="PC494_002992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF3913475.1"
                     /translation="MIKVRELKFSYGKDKQILHGLNFEVKEGEIFGFLGPNGSGKSTT
                     QKILNGVLKGYNGHVSIFGKEVKAYTESLYQKIGVLFEFPYLYTNLSAIDNLEYFSSF
                     YPKNQRRDIYELLDLLEFKKEFINKPVSSYSKGMKQRISMARALVSNPKLLFLDEPTS
                     GLDPSGAVLFRKIIEEERKKGTTIFLTTHNMLDADLMCNNVAFIADGKIMVIDKPKNL
                     KMKNSNNKVEVEFVYNGNRDIEIVDIQELESGITFKYDEILSVHSKEPTLEEVFIKYT
                     GRMLV"
     gene            4536..5564
                     /locus_tag="PC494_002993"
     CDS             4536..5564
                     /locus_tag="PC494_002993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF3913476.1"
                     /translation="MYSKFFTLVKKDFWMMIYGKFFVLTLGSLILYSCYINFGYVKFM
                     DEDSYHNNVYLYNPENISMSASPLINQVSSIGELKAKLDEDTSAVCIDMSSSKPKVIL
                     HESIKGVDNYRADYALSLLSSEKDHNSKISDNNAIIQINDKDTSEIKQRKDMTCEILF
                     FEIVAIGFLGIASLLFKEKQMGVMRITGILPVKRSLFILSKIFAFFICDLCFTVLLVV
                     FNIGFLEGIKILPQVLVQASILSIIMSLIGIGCSMLLRDFKQFSLIYLVVAVFITTPI
                     FLSANTSFEIDWIKYHPFYHVYSQLKNAFFMNFSKELVYFVVCSLTIIVLFLLVKYIF
                     NKELVREG"
     gene            5567..6580
                     /locus_tag="PC494_002994"
     CDS             5567..6580
                     /locus_tag="PC494_002994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF3913477.1"
                     /translation="MIGLRYQLKSIKKDKMCIISFFLPVVMAILINFMGTIDISSLGE
                     IRFGIVKDTLPVQTEQWLKKYGMVSVYDTKMHLIREIKDIKTDTIGVVRDGKGIKTVF
                     YGNEINAIKNVGKTLPEMFRLKGDLKDVEVTILPKDSILKEFQNVFIAMILITAMFMG
                     CTFNAMNIISEKEDGISFINEVLPQSRSQYIIQKVFLGLLCGCLSSMITVFICLDISI
                     LDMIMMLLLVVFSAFISSLIGLFIGKLSEGLMVGIVYIKIVMILFIGTPLLIYLLGVN
                     TSGIGNLCYIMPSVATFNGIMEIINGNVIIIKDIVILAVHCVVWFMIYIILDKKRKLS
                     FSR"
     gene            complement(7097..8347)
                     /gene="cme"
                     /locus_tag="PC494_002995"
     CDS             complement(7097..8347)
                     /gene="cme"
                     /locus_tag="PC494_002995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter Cme"
                     /protein_id="HDF3913478.1"
                     /translation="MENKNTNSTWKKKVILFLASQYISLFGSSLVQMAMIWYVTLQTS
                     SGVWVTVLTVCSFIPQMIISFFAGVWADYYNRKVLIIVSDSTIAISTLVLILFMMSSN
                     GTTSELIAISVISVIRSLGSGVQTPAVNAMIPQLVPEEHLMRFNGINSSLQSIVQFIV
                     PIVAAAILGFGNKINQVLLIDVFTAIIAIVLLIFIKIPKHDIPKQTEKVSFFADMVSG
                     IKYCFSDKFIRKVLFTYGAFMLLCVPSGFLIGLLIERTFGKGYIYLSIIEMIGFLGMV
                     LGGLIIGVFGGFKNRNKTFFLAILSYAIFSIILGLVTQAWQFFIFMFFTNFSIPIIQA
                     SAMTMLQEHVAPQMLGRVLSLPIIIYTGFIPLGMMIFGPMADVISINNLIIIAGIILL
                     FFALAIPYSKQFYKQGISKSNESE"
     gene            complement(8433..9179)
                     /locus_tag="PC494_002996"
     CDS             complement(8433..9179)
                     /locus_tag="PC494_002996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HDF3913479.1"
                     /translation="MDTYTTSEVADLIGVHPNTVRLYEELNLIPKPKRNTNGYRIFND
                     FHIEQFRFARTALKIEVVQRGLRKDALEIVRTSANRDFDKAISLVNQYLQQLEIEKSN
                     AEEALTIVAQILNGNTPETNKLFLTRKETAEHLNVTIDTLRNWEMNGLLKVKRKQNGY
                     RVYTDEDIKRLKIISALRCANYSLSAILRMLNALSSSPNTNIKTVLDTPKDDDEIISV
                     CDKLITSLKEAEHNAKTMKSHLQIMKKQFS"
     gene            complement(9332..10354)
                     /locus_tag="PC494_002997"
     CDS             complement(9332..10354)
                     /locus_tag="PC494_002997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase"
                     /protein_id="HDF3913480.1"
                     /translation="MNKNNCLDLIFEKVDPSSVGMSSEKLSQLEPLIISQYSNINGII
                     IARKGKIVFEKYYNGYNADDTFHVASVTKSIISALIGIAIDKGYIKDVDQKVVDFFPE
                     YTCSPSEICKKAVTIRHLLTMTAPYPFKNMTESLERLCKQKDWIKYTLNQLGQKGEIG
                     TFKYSSAGTHLLSAIITKTTGKSAREFANEYLFKPIGMKVIPDYDMKDFGFEDFFGKN
                     LKGWAKDRQGYSIGGWGLTLSARDMLRFGFLYLNDGIWNNKRIISKSWIEESVKMNSN
                     EYGYLWWLCKKDGVLWYSAMGTGGNAICCIPQYDLVIAIPSKIVFKPRDRWEFIEKYI
                     LTSIID"
     gene            complement(10354..12774)
                     /locus_tag="PC494_002998"
     CDS             complement(10354..12774)
                     /locus_tag="PC494_002998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HDF3913481.1"
                     /translation="MKEIKINGAKIHNLKNIDVSIPKDKLVVATGVSGSGKSSLMFDI
                     VFEEGRKQYLQSLGILAGIDSEDKFDNIQGLAPTIAVQQNIIRQSNPRSTVGTRTNIL
                     NMLTLLYSVEGQIMCTMCDTPVSDNLICNNCGYEEERLRPSYFSYNSSDGMCMKCSGH
                     GAYFEINIEKLVLDKHDTLKQVLDRAKITPGYLRVFSKKFNDYLDIQFLQLPEEIRNE
                     VLYGHYENGKKSSSLSKVFHNRYKRGEDLNGVYTMTACSDCNGFKIGEEARRVLLNGK
                     HIGELGKMTILEIDDFLKLLINQGNLNTFGTNLVNDILSKTQHLIESRLGHLSLYREM
                     STLSGGEMQRLFLNSHLDSEMDSLIYVLDEPTAGLHESEKIDILKSLKKLKDLGNTVI
                     VVEHDKNTIEMAEHIIDIGPKAGVEGGQLVYQGDLEGLLQSDKSLTGQYLSGKYPMPN
                     RTSNKNITHTDKIPCITIQNANTNNLKNVTVSLPLGAMVGISGKSGSGKSSLISDTLL
                     PLLRSQFNNHTINNQINSSESEIGEEDDYAVVETIADRLIGTKHISGYSEISQSPIGK
                     NMNSTPASYIGIWDKIRTLFAGQPESLEQGFTAGHFSFNSKGACPKCSGSGYEKVWLG
                     NNLSIDHICSECQGKRFNDESLSIKYKNKNIHDILNMSVSESVHFFKDIPNIVSHLNV
                     LEQIGMGYIKLGQPTPTLSGGESQRIKLAKEIGKKRNGNILYVLDEPTTGLSLYDTSK
                     LIQLLDELVENGNSVIVVEHDIDVLNVCDWIVELGPEGGDKGGYIIAEGSPKTLKENP
                     KSITGRYL"
     gene            complement(12860..13780)
                     /locus_tag="PC494_002999"
     CDS             complement(12860..13780)
                     /locus_tag="PC494_002999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HDF3913482.1"
                     /translation="MTNAKSKKEYLNRICKVQDYIEEHLHEPLSLDELSNIAGFSKFH
                     FHRIFKAIEKETLAQYVNRLKLENATAFLIHRTDMTVTDIAHYFGFTDSAVFSRAFKN
                     YYKISPIKYRNNYSKNCKEPYKISQYNRSISKPKCKNTREVKGEIEILELDNMNTIYT
                     RYTGSYGNLTSTFPKLLERLFTYASEQNLLGLENTQILAIYHDNPQFTQEHQLRTSIC
                     MTIPDNIVVKENDNLGNMIIPSGKYLVGHFDISKSEYSDAWDFMYNEWLSNGNYKLRA
                     SFPFEVYLNNPHNHPQNRHLVDIYLPIEPF"
BASE COUNT         5021 a         1820 c         2217 g         5094 t
ORIGIN      
        1 atatattcag atttattatt atattgagcc ttatattaaa ttaaggacta taatttgaaa
       61 ataagctata aaaacttaat attgttttgt tcagagataa aaaaagaata ctttaggtga
      121 tttttattaa aaattaagag tgataaaatt atatacttta taaatgtaaa tatgacgaat
      181 aaaaatgata aatataataa tatatatatt tacattagga gttttctata ctataattat
      241 ttaaaactaa atataaatgt tggaattatt taggacttga aattgtctaa aaataaatac
      301 aagtgatgaa gaggtgatgt gatgagatta gatatggata gtatgttata tgtactaatt
      361 tatatgacat tattggtatc tatcattgga agtatatttt atttttgtaa agacctctta
      421 aatcataaaa ttaagtatgt tttaataaga gacatatttg taaatagaat tacatattct
      481 gaagaacgac tgcctaaaca gtatatagtt tttcagaaat atgatatttg gaggtattgt
      541 agtttgtttt aatttgaaat gaatctatta taaattctaa agtttaaaaa taaaaaggag
      601 agaataaaat ggatttcatt tcaagtatat tgcaaggatt attaagtata ttatttaatt
      661 ttacaggtga ttttggaatt tctattgtac ttataacttt aatagttaaa ttagtactta
      721 tgccactatc attaaaacaa agattttctg taaaaaaaca gcaagaatta gctgaaaaaa
      781 tggaatatat aaaagaaaag tataagaatg atactaaaga attggaaaag caaatacaag
      841 taagttctgt agaaagtatg aagagtatgc tgggatgtct tatagttttg gttcaaatgc
      901 cagtagtata tgctttatat catgtatgtt tagatatgac aaaggaattt acaacaatta
      961 taattccatg gattgctaat ttaggtacat ttgataattt gtttatatta ccttgtatat
     1021 atacattaat tatgttagct tcaaatttag tgaattatat accatattta aaaataaatt
     1081 ctcaagtaaa gtttaacaaa caaatggctg tggtgactac cataacaagt cttatactaa
     1141 ctgttagaac tccagtagcc ataggtctgt actttataac aagtgcaatt tattcattaa
     1201 ttgaagatat ttgctttaga atatatttta atcgaaaaaa tagaatagtg acaaaataat
     1261 ataattatta ttagaaatat tttagcctgc taacatagaa aaagttagta ggctattttt
     1321 atctatgata tcaattccat taagaatagt ctaaaaaata ctatcaaaat gctataaaaa
     1381 atactataaa aaaatagttg aaaaataaat aaattaatat aaactaaaat aaagcctaca
     1441 aaaaagaggt gataaataga aatggctaaa atactagttg tagaagatga aaaaagaatg
     1501 caaaatatta ttgtagaata tatgcaaaag ggaggatata cttgtataac tgctgatgat
     1561 ggagtcgagg cacttacaat attaaagagc aacaatatag atttaatgat attggatatt
     1621 atgatgccgt atttagatgg attttcagtg tgtagagttt cacgtgaaat gactaatata
     1681 cctattatta tattgacagc taaaggtgaa gaggaggata aattaaaggg ttatgaatat
     1741 ggcgcagatg attatataac aaaaccattt agcccaaaag tacttttagc aaaagttaat
     1801 gctttgttac gtagatacac tactgatatt cccaaaaatt cattgagttt aggaaagatt
     1861 tttattatgg tagcatcaag acaagtgtat gtagaagata aattgattga tttaacatat
     1921 aaagaatttg aattattgcg tttatttatg gaaaacccta atcaagtttt ttccagagag
     1981 aaacttttaa attgtatatg gggatatgat tttgaaggaa acacacgaac tgtagataca
     2041 catataaaaa ccttacgcaa aaagcttggt agtgaaggac accatatagt tacattaatt
     2101 cgttcaggat ataagtttga ggttaaggaa tgaatagttt aagaaagatt atagaaaaac
     2161 tgaaaaatgt agatatttca aattggatta aacaaaattt tggactatat tcagttagaa
     2221 aaaaagtgtt tttactttct aaattatcag gagcgttaat tatattattt tatctggttg
     2281 ttgaagaatt ttcgataaac tctaaatttg aattttggat ttggtttata atactggtta
     2341 tatttattat gagtattgat ttcttattgg gaaaatttat ttcagaacca atcacatcta
     2401 taaataaatc tgcaaaaagt atgtcccaac ttgatttttc taatccatgt actgtaaata
     2461 ctaatgatga atttggagaa ctttctagga gcctgaatac aatgtctaca aatctacaac
     2521 aggcattatc agacctagaa agtgcaaata ttcaacttga aaaggatgta aataaggaaa
     2581 gaatgctatt ggaacaaaga aaggagttgg tagatacaat ttcacatgaa atgaagactc
     2641 cacttggcat tatacgtgcg tatacagagg ggcttataga tgaagttgat gaagaaaaaa
     2701 agaaaaatta tatgaatgtt ataatagaag aaactgatag aatgaacaat atgattgtat
     2761 cattattaga cttatctgca ttggaagcag gagtttctaa acttaaccca gagcgttttg
     2821 attttataga gtttgttgaa actgtggcag gtcgtctttt aattgatata ccagatgcca
     2881 atttttattt tacatatgat ttgccagagt atgaagtttt tgtagtggca gataaaatga
     2941 gaatggaaca agtagtagag aatctagtta ttaatgcaaa gaagcatgtt gtatataatg
     3001 gtaatttaga tttatcgatt acatgtgaaa atggcttgct tttatttgaa atttataatg
     3061 atggtaggtt tatagagcaa gatgagattt caaagatttg gtctaagttt tatcgtagtg
     3121 ttcaatctca gcgtacagga ggttcaggtc tagggcttgc aattgtttca caaatactta
     3181 caatgcaagg gttagaatat ggagtgaata atcgtgatag aggagtagag ttttatttta
     3241 tgattccaat tgatgaataa tttagtatta atttataaat tataagtatc tgatgtaaaa
     3301 tatttttatt tgtatacgta agtatttaaa gagaataaaa taaaaaaact taatgaaaaa
     3361 gcttaatgaa aaagtctaat aaaaagctta atgaaaagct taataaaaag tcttgttttc
     3421 ctgatgaaaa caagattttt tattaagctt tttattattt cacttcgatt tcacaagaga
     3481 gacactctga tttcaccaaa tagaaataaa ataggttaaa taaattaaaa aatagaagcg
     3541 taattaaata aggttacaag ggggagtact tatgaaatgg tatacatggt tgactattat
     3601 attgataata ttgctttcta ttccgcttaa aattaaattt ataaaatggt gggatagacg
     3661 acaaaaaaat gataaaggag gttatgatag atgataaaag taagagagtt aaaattttct
     3721 tatggaaaag ataaacagat attgcatgga cttaattttg aagtaaaaga aggagaaatc
     3781 tttggattcc ttggacctaa tggttcagga aaatccacaa cacagaaaat cttaaatggt
     3841 gttttaaaag gttacaatgg tcacgtatcc atttttggta aggaagttaa agcatacaca
     3901 gaatctttat atcaaaagat tggtgtttta tttgaatttc cttatttata taccaattta
     3961 agtgcaattg ataatttaga atatttttcg tctttttatc ctaaaaatca aaggagagac
     4021 atatatgaac tcttagattt gttagagttt aagaaagagt ttataaataa gcctgtatca
     4081 tcctactcaa aaggtatgaa gcaacgtatt agcatggcaa gagcattggt aagtaatcca
     4141 aagttgttat ttttagatga gcctactagt ggacttgacc catctggagc tgtactattt
     4201 cgtaagatta ttgaagaaga acgaaaaaaa ggaacaacta tctttttgac tactcataat
     4261 atgctagatg cagatttaat gtgtaacaat gtggctttta ttgcagatgg aaagattatg
     4321 gtaatagata aacccaaaaa tttaaaaatg aaaaatagca ataataaagt tgaagtggaa
     4381 tttgtatata atggaaatcg agatattgaa attgtagata tacaagagtt agaatctgga
     4441 ataactttta aatatgatga aatcttaagt gtacattcaa aagaacctac actagaagaa
     4501 gtttttatta aatacacagg aaggatgtta gtgtaatgta ttctaaattt tttaccttag
     4561 taaaaaaaga tttttggatg atgatttatg gtaaattttt tgtgctgaca cttggctctc
     4621 tcatacttta ttcgtgttat attaattttg gttatgtaaa gtttatggat gaagatagtt
     4681 atcacaataa tgtatatcta tataatccag agaatataag catgagtgca tctccattaa
     4741 ttaatcaagt ttcttctata ggtgaattaa aagcaaaact tgatgaagat acaagtgcag
     4801 tttgtattga tatgagttcc agtaagccga aagtaatttt acatgaaagt attaaaggag
     4861 ttgacaatta tagagctgac tatgcattgt cattattatc atcagaaaaa gaccataata
     4921 gcaaaatatc agacaacaat gcaataattc aaattaatga taaggataca tctgagataa
     4981 aacaaagaaa agacatgact tgtgagattt tattctttga aattgtagct attggatttt
     5041 tagggattgc ctctttatta tttaaagaaa agcagatggg agtaatgcgt attactggta
     5101 ttttacctgt aaaaagaagt ctttttatat tatcaaagat atttgctttt tttatatgtg
     5161 acctatgttt tacagttctt ttagtagtat ttaatattgg atttttagaa ggaataaaaa
     5221 tacttccaca agtattagtt caagctagta ttttatcaat tattatgtct ttgattggaa
     5281 taggatgctc aatgttattg agagatttta agcaattttc tcttatatat cttgtggttg
     5341 ctgtattcat aactacacct atatttctat ctgcaaatac atcttttgaa atagattgga
     5401 ttaaatatca tcccttctat catgtttata gtcagcttaa aaatgcgttt ttcatgaatt
     5461 tttcaaaaga attagtttat tttgtagtgt gttctttgac aataatagtt ctatttttac
     5521 ttgtaaaata tatttttaat aaagaattgg ttagggaggg ataatcttga taggattacg
     5581 ttaccagtta aagagtataa aaaaagataa aatgtgtata atttccttct ttttaccagt
     5641 tgttatggcg attttaataa attttatggg aacaattgat atatcttcat taggagagat
     5701 acgttttggt atagtgaagg atacacttcc tgtacaaaca gagcagtggt tgaagaagta
     5761 tggtatggta agtgtatatg acacaaaaat gcatttaata cgtgaaatta aggatattaa
     5821 aacggacaca attggagttg ttagagatgg taaaggaata aaaactgtgt tttatggaaa
     5881 tgagattaat gctataaaaa atgttggaaa gacattgcca gagatgttta gactaaaggg
     5941 tgatttaaaa gatgttgagg ttacaatatt gcctaaagat agtattttaa aagagtttca
     6001 aaatgttttt attgctatga ttttaattac tgctatgttt atgggatgca cctttaatgc
     6061 aatgaatatt atatcggaaa aagaagatgg aatatcattt ataaatgaag ttttgccaca
     6121 gagtagaagt cagtatatta tacaaaaagt atttttgggt cttttatgtg ggtgtttatc
     6181 ttcaatgata actgtattta tatgtttgga tatttcaata ttagatatga taatgatgtt
     6241 gttactcgtt gtattttcag catttatttc atcacttata ggtttattta ttggaaagtt
     6301 gtcagaaggt cttatggtag gaattgttta tattaaaata gtaatgattt tatttatagg
     6361 tactcctttg ttaatatatc ttctaggggt taataccagt ggtataggga atttatgcta
     6421 tataatgcct tcagttgcta catttaatgg tattatggag attattaatg gtaatgtcat
     6481 tattatcaaa gatattgtaa ttttggctgt acattgtgta gtatggttta tgatatatat
     6541 tattttagat aaaaaaagaa agttatcttt tagtagataa ctcagtataa ttataattgg
     6601 gacaatttaa taggtgattt aatatacttt gtatagtgta atttatgtag tgcaatttgt
     6661 atactttaat ttatgtagtg taatagttag ttttatttta taattattca atataattta
     6721 gtaagaagtt cagtacaatt agagctactt agtggaaaac ttaataggta cttaaactat
     6781 ataaatactt tattttcctc catttgtact ataaatttaa tttatgatat aaatggaggt
     6841 attattatat gatttgataa atttcatcat tataacctac aagtaaaggt attattatat
     6901 aaagttaata aagatagtat caaaatatta tttgctataa agagagggac tcaaaataaa
     6961 gataaaccta tttttcaatg ttgaaatgat aaaatatatt tgatttcata taaaaaattt
     7021 tcttcataaa ttaaaaagtc cattttaagc cccttcattt ttaaccagat aaatcgagtt
     7081 aaactattta aatatattac tcggattcat ttgacttaga tattccttgc ttgtaaaatt
     7141 gttttgaata ggggatagcc aaagcaaaaa ataaaagtat aatccctgct atgattatta
     7201 aattattaat agaaattaca tctgccattg gtccgaaaat catcatacca agaggaataa
     7261 aaccagtata tataataata ggtaagctaa gaactctacc tagcatttgt ggtgctacat
     7321 gctcttgcaa catagtcata gctgatgctt gaatgattgg aattgaaaaa ttcgtaaaaa
     7381 acataaatat aaaaaattgc caagcttgtg ttacaagacc tagaataatt gaaaaaatag
     7441 cataggataa tattgctaga aaaaaggtct tatttctatt tttaaaacca ccaaaaactc
     7501 ctataatcaa tccacctaaa accataccta aaaatccaat catttcaata atagacaggt
     7561 atatataacc cttgccaaat gttcgttcaa taagaagtcc tataagaaat cctgatggaa
     7621 cacaaagaag catgaatgct ccataagtaa aaagcacttt tctaatgaac ttatctgaaa
     7681 aacagtactt tatccctgat accatatctg caaaaaatga gactttttca gtttgttttg
     7741 gtatatcatg tttaggaatt ttgatgaata ttaataatac aatagcaata attgcagtaa
     7801 atacatcaat taaaagaact tgatttattt tattaccaaa tccaagtatt gcagcagcta
     7861 caataggaac tataaattgt actatagact gtagactact atttatacca ttaaaacgca
     7921 ttaaatgttc ttctggtaca agttgaggaa tcattgcgtt tacagcaggt gtttgtacac
     7981 cacttcctag tgaacgtata acagatatta ctgatatggc tattaattca cttgttgtgc
     8041 catttgatga catcataaat agaattagaa ctaatgtaga tatagcaatt gttgaatctg
     8101 atacaattat gagtaccttt cgattgtagt agtctgccca tacaccagca aaaaaagaaa
     8161 ttatcatttg aggtataaag gagcatacag ttaaaactgt tacccataca cctgatgatg
     8221 tctgaagtgt gacataccat atcattgcca tttgtacaag tgatgagcca aataaggaaa
     8281 tatattgact tgctaaaaaa agaatgactt ttttcttcca tgtagaatta gtatttttgt
     8341 tttccatcct attcctcctt tgatttgtgt gttgaatttt tcttgctctt aaggataaca
     8401 cacaaatcaa agtctggagt tagagtggag ggctaggaaa attgtttttt cataatttga
     8461 agatgagatt tcatggtttt tgcattatgt tcagcttctt tcaatgaagt tatcagtttg
     8521 tcacacactg agataatttc gtcatcatct tttggagtgt caaggacagt tttaatatta
     8581 gtattaggac tagaagataa agcatttaac attcgtaaaa tagctgaaag agaatagttt
     8641 gcacaacgaa gtgcgcttat aattttaagt cgttttatat cttcatcagt atatacacga
     8701 taaccatttt gttttctttt tacttttaac aaaccattca tttcccaatt tcttaaagta
     8761 tctattgtaa cgtttaagtg ttctgcagtt tcttttctag ttaaaaagag tttatttgtt
     8821 tctggagtat ttccatttaa aatctgtgca acaatagtaa gtgcttcctc ggcattagat
     8881 ttttctattt ctaattgttg caagtattga tttacaagac taatagcctt atcaaagtcc
     8941 ctattcgctg atgttcttac aatctcaagg gcatcttttc ttaatcccct ttgtaccact
     9001 tcaattttca aggctgtacg agcaaatcta aattgttcta tatgaaaatc attaaagata
     9061 cgataaccat tggtattacg cttaggttta ggtattaagt ttagttcttc atataaacgt
     9121 actgtattag gatgtacacc aattaaatct gctacctctg atgtcgtgta agtgtccatt
     9181 agtattcaac tccttttaga tatatagtat tagtcataat aacaccaaac aaaagtctgg
     9241 tgttataatg gagggtttgg ctatctaaga gtaattagtt tatgaaagag taattagttt
     9301 atgaaagagt aattagttta tgaaagagta attaatctat tatagaagta agtatatatt
     9361 tttcaatgaa ctcccatcta tcacgaggtt taaacactat tttagatggt atggctatta
     9421 ctaagtcata ttgtggaata caacaaatag catttcctcc agttcccatt gctgaatacc
     9481 acaaaacacc atctttttta catagccacc acagataacc gtattcatta ctattcattt
     9541 taactgattc ttcaatccac gatttagata taatacgttt attattccaa ataccatcat
     9601 ttaaatacag aaaaccaaat cgcaacatat ctctagcact caatgtaagt ccccagccac
     9661 ctatagaata accctgtcta tcttttgccc aacccttaag attttttcca aagaaatctt
     9721 caaaaccaaa atctttcata tcataatctg gtataacttt cataccaata ggtttaaata
     9781 agtactcatt agcaaattca cgagcagatt ttccagtagt ttttgttata atagctgaaa
     9841 gtaggtgcgt tccagctgaa gaatatttga aagtaccaat ttcgcctttt tgaccaagtt
     9901 gattcaaggt atattttatc caatcttttt gtttgcaaag tctttctaaa gactcagtca
     9961 tatttttaaa agggtatggt gcagtcattg taagtaggtg acgtatagtt actgcttttt
    10021 tacatatttc agaaggacta caagtatatt caggaaaaaa atcaacaacc ttttggtcaa
    10081 catcttttat atatccttta tctattgcaa tacctattaa ggctgatata atactttttg
    10141 taactgatgc aacatgaaaa gtatcatcag cattatatcc attatagtac ttttcaaaga
    10201 caatttttcc ttttcttgca ataattatac catttatatt gctatattgt gagattatta
    10261 aaggttcaag ttgtgaaagc ttttctgaac tcataccaac acttgaaggg tctacttttt
    10321 caaaaattaa gtctaagcaa ttgtttttat tcattaaaga tacctccctg ttatagattt
    10381 tggattttct tttagagttt ttggagaacc ttctgcaatt atataacctc ctttgtcacc
    10441 accttctgga ccaagctcaa caatccagtc acaaacattt aatacatcta tatcatgttc
    10501 aacaacaatt acagaatttc cattttcaac caattcatct aataattgaa tcaacttaga
    10561 agtatcatat agacttagac cagtagttgg ctcatccaat acataaagga tattaccatt
    10621 tcgtttttta ccaatttctt ttgcaagttt gattctttgg gattcaccac cacttaaagt
    10681 cggtgtaggt tggcctaatt ttatataccc catacctatt tgttctaata catttaagtg
    10741 tgaaacaata tttggaatat ctttgaagaa atgtacagat tcagaaacac tcatatttaa
    10801 aatatcatgt atatttttat ttttatattt aatagataaa gattcatcat taaatctttt
    10861 tccctgacat tcactgcata tatggtctat acttagatta tttcccaacc agaccttttc
    10921 atatccacta ccactacatt taggacaagc ccctttggag ttaaatgaga aatgaccagc
    10981 tgtaaatcct tgttctaacg attctggctg acctgcaaat agtgtacgta tcttatccca
    11041 tataccaata taagaagcag gagttgagtt catatttttg cctataggag attgagatat
    11101 ctctgaatat ccagaaatat gtttagtacc aatcagtcta tctgcaatag tttcaacaac
    11161 tgcataatcg tcttcctcac ctatttcact ctctgaagaa tttatttgat tattgatagt
    11221 atggttatta aattggcttc taagaagagg aagtagggtg tctgatataa gtgaactctt
    11281 gccactacct gattttccag atattccaac catagcaccc aaaggtaatg atacagttac
    11341 atttttaaga ttatttgtat ttgcattttg aatagttata caaggtattt tatcagtatg
    11401 tgtaatgttt ttattgcttg ttctattagg cattggatat tttccagata gatactgtcc
    11461 agtaagtgat ttgtcggatt gaagtagacc ttctaaatct ccttgatata ctaattgacc
    11521 accttcaaca ccagcttttg gaccaatatc aataatatgt tctgccattt caattgtgtt
    11581 tttatcatgc tcaactacta tgaccgtatt gcctaaatct ttaagtttct ttagtgattt
    11641 taagatgtct attttttctg attcatgcaa tccagctgtt ggttcatcaa gcacataaat
    11701 taatgagtcc atctctgaat cgagatgtga atttaaaaat agtctttgca tttccccacc
    11761 actcaaagtt gacatttctc ggtataagga tagatgacct aatcgtgatt ctattaaatg
    11821 ttgagttttg gataaaatat catttacaag atttgtacca aatgtgttta aattaccttg
    11881 atttattaag agtttaagga aatcatcaat ttctaaaatc gtcatttttc caagttctcc
    11941 aatatgtttt ccgtttaaaa gtactctacg tgcttcttca ccaattttaa aaccattgca
    12001 atctgaacag gcagtcatag tataaactcc atttaaatct tcgccccttt tgtaacgatt
    12061 gtgaaatacc tttgataaag aggaactttt tttaccattt tcataatgac catagagtac
    12121 ttcatttctt atttcttcag gtagttgtaa gaattgtatg tctaaataat cattgaattt
    12181 tttagaaaat actctcaaat atccaggtgt aatctttgct ctatctaaga cttgttttag
    12241 ggtatcatgc ttatcaagga ctaatttttc aatattaatc tcaaaatatg caccatgtcc
    12301 agagcacttc atacacattc catctgaaga gttgtatgag aaataacttg gtcttaatcg
    12361 ttcttcctca tatccacaat tattgcaaat tagattatcg cttacaggag tatcacacat
    12421 agtacacatt atttgacctt ccactgaata caatagtgta agcatgttga gaatattggt
    12481 tcttgtgcct actgttgaac gaggattgct ctggcgaata atattttgtt gaacagctat
    12541 agtgggagct aaaccttgaa tattatcaaa cttatcttca ctatcaatac ctgcaagtat
    12601 acctaaagat tgcagatatt gtttacgccc ttcctcaaat acaatgtcaa acataaggct
    12661 agacttacct gagccactga cacctgttgc aacaacaagc ttatcttttg gaatagaaac
    12721 atctatattt ttaagattgt gtatctttgc tccattaatt tttatttctt tcattggttc
    12781 acctcatttt atcaatttta tcaaaccgta aaatagggat atattaatcc ttaatacaag
    12841 aatagattag gtgaggttat taaaaaggtt ctataggtaa atatatatcg accaagtgtc
    12901 tattttgagg gtgattgtgt gggttgttaa gatatacttc aaaagggaag gaggcacgta
    12961 gcttataatt accatttgat agccattcat tatacataaa atcccacgca tcactatatt
    13021 cagattttga aatatcaaaa tgtcccacaa gatattttcc agaaggtatt atcatattgc
    13081 caagattgtc attctctttg acaacaatgt tatctggaat ggtcatgcaa atactagtcc
    13141 ttaattgatg ctcctgtgta aattgtggat tatcatgata aatggctaat atttgtgtgt
    13201 tttcaagtcc aagtagattc tgctcacttg catatgtgaa taaccgttct aaaagttttg
    13261 ggaaagtact ggttagatta ccatatgaac cagtatatct agtgtaaata gtattcatat
    13321 tatcaagttc tagaatttca atttcacctt taacctctct agtattctta catttaggtt
    13381 ttgatatgct tctattgtac tgagaaattt tatatggttc tttgcaattc ttgctataat
    13441 tgtttctata ttttataggg cttattttat agtaattttt aaatgctctc gagaaaactg
    13501 ctgaatcagt aaagccgaag tagtgtgcaa tatcagtaac agtcatgtca gttctatgaa
    13561 taagaaaagc agttgcattt tctagtttta gcctatttac atattgtgcc aaagtttctt
    13621 tttctattgc tttgaagatt ctatgaaaat gaaattttga aaaacctgct atattagaaa
    13681 gttcatcaag agaaagaggt tcatgtaaat gttcttctat atagtcttgc actttgcaaa
    13741 tacgatttag atattctttt ttacttttag catttgtcat atatagccct ccttattgtg
    13801 taaaatgtgt atcaattaat ttatagcaat atagtaataa aattttatgt ttttgtaatt
    13861 tatgataaat aagatagcgt ttaatttttt ataattgata aaagatataa gatgccttat
    13921 atttgtcttt gcatataagt atagtcttcg taataattag tataccatag tgatttattt
    13981 ttaattgtgt atttatataa atacacaact tatgatatgg acgaattatt atgcaaataa
    14041 gctgtaatta aataaattgc aatataaacc agttgaaaca taagttaggg aaatattatc
    14101 aaagttatta cttagcataa gagtatagat ggaataaaat aagattaaaa aa
//
LOCUS       DAMKNB010000088        14041 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.094, whole genome shotgun sequence.
ACCESSION   DAMKNB010000088 DAMKNB010000000
VERSION     DAMKNB010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 14041)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14041)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14041
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.094"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            431..1324
                     /locus_tag="PC494_003000"
     CDS             431..1324
                     /locus_tag="PC494_003000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfide/dihydroorotate dehydrogenase-like
                     FAD/NAD-binding protein"
                     /protein_id="HDF3913483.1"
                     /translation="MSNKIVSKRQLTDSIYLMEIEAPRVAKSSQPGQFIIIKNDEKGE
                     RIPLTIADYDREKGTVTIVFQTVGASTKKLAMFEENDFVMDFVGPLGQASEFIHEDIE
                     ELRNKKILFVAGGVGSAPVYPQVKWFKEHGLDVDVIIGARTKELIILEDDMKKVAKNV
                     YVSTDDGTYGFNGRVTDLLKDLVDNQGKKYDQAIVIGPMIMMKFMCQLTKELNIPTIV
                     SLNTIMIDGTGMCGGCRVSVGNETKFACVDGPEFDGHLVDFDQAMRRQSMYKTQEGRA
                     MLKLEEGDSHHHSNCGCGGNK"
     gene            1324..2718
                     /gene="gltA"
                     /locus_tag="PC494_003001"
     CDS             1324..2718
                     /gene="gltA"
                     /locus_tag="PC494_003001"
                     /EC_number="1.4.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent glutamate synthase"
                     /protein_id="HDF3913484.1"
                     /translation="MDAKKVKVPVREQEPAVRATNFDEVCLGYNKEEAMAEANRCLAC
                     KKPKCVGGCPVGIDIPGFITKIKEDDIEGAAKVIAKSSSLPAVCGRVCPQESQCEGVC
                     ILGIKSDAVSIGKLERFVADWSKENDINLSDTEPKKNQKVAVIGSGPAGLACAGDLAK
                     KGYDVTIFEAMHEPGGVLTYGIPEFRLPKQAVVQPEIDNIRKLGVKIETNVIVGKTIT
                     VDELIEDEGFEAIFIGSGAGLPMFMNIPGENANGVFSANEFLTRVNLMKAYRDDYDTP
                     ISSGKKVAVVGGGNVAMDAARTALRLGSESYIVYRRSEKELPARAEEVHHAKEEGIIF
                     NTLTNPKEILVDENGYVKGMVCIRMELGEPDDSGRRRPIEIEGSEFVLDVDTVIMSLG
                     TSPNPLISSTTKSLDINKKRCLITDENGQTSKEGVFAGGDAVTGAATVISAMGAGKTA
                     AASIDEYLKAKVNA"
     gene            3084..5303
                     /locus_tag="PC494_003002"
     CDS             3084..5303
                     /locus_tag="PC494_003002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HDF3913485.1"
                     /translation="MKKREKVFDGLVFKHILILLILLVLIDLTSTIIYASNSMEITSR
                     NMIEASKRELENYLEVNISLLKALSQDDRFSNGETSLIEKGKLLSPYQKEYNLFMIGI
                     TDTKGNASSTYRENVNSIKDKPSFEKAIKTKQVVVSDIEVSNVTGDKVFIIYVPIVKN
                     NEMIGTIFASFYFQDVNNLISRSNFDDSIKFLMIDKDYTIISHPNKKYVNDKSKMLDL
                     EGNIIGTTKSEILKNINKKCQGDFLSWDNWRLYNVKYTNIKWTNWTLVSKCNIFKNFK
                     NLIVNFMIKLYFYIVIFMILWKLSNAKLIEQLKKLAYYDSLSGIKNKEKFRKDSMYIL
                     KNYYQDNFYLVQLDVNKFKYINEMFGYAEGNKILIHISQVLNNNTNKYEICARMDNDH
                     FILLIACNTEDELLNRLSKINKEICNLNTTNSSKYKIVMSSGIYKITKKDDIKKIDLL
                     IDRANIAAKSKKEKYEHSYSFFNEDTRNRLYKEKRLEDNMNKALEKGEFIVYYQPKYS
                     LDDVNEIEGAEALIRWNSPEFGFISPIDFVPLFEKNGFIVNIDMFVFEEVCKTLNKWI
                     NKGYTPVPISVNMSRVHLYRDNFIENITDLISKYNISPEFIELELTESVVFDNLNILI
                     DIMKKIKEIGFLISMDDFGSGYSSLNLLKDLSFDILKLDRGFLIETTDTKRGKIIISK
                     IVEMAKAIDIKVICEGVETYEQVEFLKEIGCDKVQGYLFAKPMVLDEFEKHLNFKFD"
     gene            5450..6196
                     /locus_tag="PC494_003003"
     CDS             5450..6196
                     /locus_tag="PC494_003003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014466367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF3913486.1"
                     /translation="MNILSIRNISKTYCGNIPFKALDKVSLNIEKGEFVSVMGPSGSG
                     KSTLLNIISTVDRQSEGEVVLDGYDVSKLKGEKLAEFRRKQLGFVFQDFNLIDTLTVG
                     ENIMLPLTLEGASIKDMNIQTKSISKFLGIDKILDRKTYEISGGQAQRCAIARAIINK
                     PAILLADEPTGNLDSKSTDDVLKLFTRINKEQKVTTLMVTHEAYSASYSDRVIFIKDG
                     CIYTEIKKSESSNSFYSDILAVLSQIGGVR"
     gene            6196..8076
                     /locus_tag="PC494_003004"
     CDS             6196..8076
                     /locus_tag="PC494_003004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF3913487.1"
                     /translation="MDFRKFAYNNIVRNFRAYLAYFLSSVFSIMIFFVFAVSMFHPII
                     TKSGMQSGSTAFMALMTSELIIFGFSLLFILYSLGNFLKYRLKDFGVLMIIGMSNRQL
                     KKLILIENLIIGFLAVMLGILLGLSISKLFLLYLSKLFYMNLTEFYFPVKAMLLTIVS
                     FMILFLITGPMSLKLLSKKSILELLVGTKKPKKEIKSSKLFGIIGVICLILGYAMILF
                     GNKLKINGGMYTTALLITLGIFLFFSQFTILILKYLKNKEKFYKNKVNMLLISNLIYK
                     LKDNTRLLFLITILLSATLVAFTTTSTLVSSQGEASKNNFPMVYSYFSEHNNEKEYEE
                     LQQIREAIKGYDYKELSFPVLKYNREVLLSVKNYNKLSKELGLDKISSKLEKYEGIII
                     PSSNSQEHINSLKQLKNYSIKNLNIEVKKSKNKIIFPTGLFSKVVVISDDLYNEVKGE
                     FSKINFHGFDYKNWQSSAKITENLKEKHFNLDREYNRSYFLTLPDMYLVELQQSKILQ
                     FMGVFIGVILFIAVFSFLYFRLYTDEIEDNVKYKKLSKIGLSFKNMNKIVSIEIGTLF
                     FIPYFIAIINSIISLLFLNQVLNNSFKLENLGILLLISSIYSLYFYLLKKNYTRKVWF
                     FD"
     gene            8195..9586
                     /locus_tag="PC494_003005"
     CDS             8195..9586
                     /locus_tag="PC494_003005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HDF3913488.1"
                     /translation="MENQQLLGTERISKLLLKYSIPAIIGMLVNSLYNVVDRIFIGNI
                     PGVGPLAITGLGVTMPIMTIILAFGMLIGIGTTTTISIKLGQGKVEEARKLIGNAMTL
                     SVITGIIIMILGILFANKILTLFGASENTLIYAKSYINIILLGTVVNLLSFSLNHSIR
                     ADGSPKISAGIMIVGCLTNIVLDWILIFGFNLGIQGAAIATVTSQALTAILTIGYYIS
                     GKSNLRFSKSNLKLDKKLIKAVFAIGMSPFAMQLAASLVQVISNIALKTHGGDLAIGA
                     MATISSIAMVFLMPIFGINQGAQPIIGFNYGAEKYDRVKKAYLGSLVVATIILCMGMV
                     VVMLFPEAIIGIFNKDPELMNISVNGLRIYLLMLPIVGLSVTGTNFIQSIGKAKMAML
                     LSLLRQVILLIPAVLILPTFLGLQGVWTAQPVSDFIATVITGIVVFRELKRYTPKTEK
                     LNENERLNEITTE"
     gene            9693..10733
                     /locus_tag="PC494_003006"
     CDS             9693..10733
                     /locus_tag="PC494_003006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic family protein"
                     /protein_id="HDF3913489.1"
                     /translation="MEFTKKSKLKNMYVNMNVARMLSKINEYKGRQLLYKKQPKEILE
                     NLEKKSLVDCSESTYIGNQRDSSNFNLEKLISNEVTPRSREELSIVEYRDVVKTINSA
                     YESIPISSQTILELHGYLYKFSSTRGGSYKSDNDFIEHNLKPSEFISTDSSVNKVEKA
                     VEEICEAYNTLIEEDEIDILILISAFVLDFILIHPFKEGNIKMARVLILLLLNKNGYE
                     VGRYISLGKIFDDSSYEYYSNLNYLKASIGSEKADMNAWIEYFLETILTAYEKLDDSL
                     NISDKKRQTKTSRIEKIINSTLGYFTKEDIRDLCPDIPEPTINRVFNNLRKQDKIEVV
                     ARGRSAKWKKKY"
     gene            11222..11875
                     /locus_tag="PC494_003007"
     CDS             11222..11875
                     /locus_tag="PC494_003007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HDF3913490.1"
                     /translation="MKKKLLYINVNSKPEDLSSSKTVARKFINKFMEKNKDFEVEEID
                     LYKEHIPRLEYQYFEKRNSIVSEENAKNLDDKDRKELTKIRNLCDQFVNASVYVIAAP
                     MWSLSFPAPLKEYIDCIIQDGKTISFEGNDKPQGILNDIDRSMVYIQSSGGHIPWVLK
                     PVMNKGLNYVESIMKFIGIKKFDELLVDGTGTSEEERQAAIEKASEKIDGIIDGMKF"
     gene            11951..12160
                     /locus_tag="PC494_003008"
     CDS             11951..12160
                     /locus_tag="PC494_003008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3913491.1"
                     /translation="MREEKSNEKYDCYWCNQENNFCVEIKDNIVMIDDGTGTLKQAVF
                     IGYKQIQINLNCSHCQNLNRIKLNL"
     gene            complement(12300..12866)
                     /locus_tag="PC494_003009"
     CDS             complement(12300..12866)
                     /locus_tag="PC494_003009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HDF3913492.1"
                     /translation="MMNNELNTIILETLNNADITSNDIPSIDLYMDQIISLIDNKLSA
                     NKRFESDKILTKTMINNYSKEGLIKPVKGKKYTKEQILQMIIIYSMKNTLTIQEIKRI
                     LHGVYEKDNFSEKDLVSCYEKFMLIKENQRKNIPDFIESNFENISINPENKDDLLIAL
                     LSLTSMADQLKNISEKLVDRYFPDITKK"
     gene            13027..13680
                     /locus_tag="PC494_003010"
     CDS             13027..13680
                     /locus_tag="PC494_003010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HDF3913493.1"
                     /translation="MYQFFLKGRDPISSLTHFIGACLSLLATIILVFQSVTLQETSLL
                     MIVSVSVFGLSLIALYSASSYYHFLKGTPEQELFFRKVDHAMIYVLIAGSYTPICLNF
                     MEKKEGIIFVTAIWIVAFIGIIIKIFWMDAPRWLSTSIYLLMGWAIVFDINAFNSIPK
                     DCLRLLIMEGVSYSIGAIIYIIKKPNISPEFGFHEIFHIFIMIGSLFHFLAVLLYVL"
     gene            complement(13838..14014)
                     /locus_tag="PC494_003011"
     CDS             complement(13838..14014)
                     /locus_tag="PC494_003011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3913494.1"
                     /translation="MYKYDDYVNLTNDLDLPVEIRNKCVRIVSVSENLEDIIIVHKFK
                     LYVVNEKYIKGIME"
BASE COUNT         5500 a         1390 c         2374 g         4777 t
ORIGIN      
        1 aatatgaaag ctggtattgc aatagattaa agccttatac acgtttagtt tttaaagaaa
       61 ttagtgttat tatgaaaacc taagttaatt tattaaataa ataattgaat aaaaaaattt
      121 tattatgtat ttataaaatt tttgttacaa atttggcata atatagtata ctttaagtgt
      181 gtattaggtt aaatctataa caaattagac gtatgatata gacttagtgt ttattggcat
      241 ttacaagaaa tttgttaata tcaactattt gtagtttggg cagttataat tattataggg
      301 gggatgtcca atacaaaaca atcaaccaag aactaatatt atattataaa gagttatagt
      361 tttgtgtgtt tatgttttta attaaattta aagtgggaaa aatatatttg ttagaatgga
      421 gaatagcgag atgagtaata aaatagttag taagagacaa ttaacagata gtatttattt
      481 aatggaaata gaggcaccta gagttgcaaa atcttctcaa ccaggtcaat ttataataat
      541 taaaaatgat gaaaaaggag agaggattcc tcttacaata gctgactatg atagagaaaa
      601 aggaacagta actattgtat tccaaacagt tggtgcttca actaaaaagt tagcaatgtt
      661 tgaagaaaac gattttgtaa tggattttgt agggccatta ggacaagcaa gtgaatttat
      721 acatgaagat atagaagaat taagaaataa aaagatatta tttgtagctg gtggagttgg
      781 ttctgctcca gtttatccac aagttaaatg gtttaaagag catggattag atgtagatgt
      841 aataattggt gcaagaacta aagaattaat tatattagaa gatgatatga aaaaagtagc
      901 taaaaatgta tatgtatcaa cagatgatgg tacatatgga tttaatggaa gagttacaga
      961 cctattaaaa gatttagttg ataatcaagg taaaaaatac gaccaagcaa tagtaattgg
     1021 accaatgata atgatgaaat ttatgtgcca attaactaaa gaactaaata tacctactat
     1081 agtaagttta aatacaataa tgatagatgg aacaggtatg tgtggtggtt gtagagttag
     1141 tgttggaaat gaaactaagt ttgcatgtgt agatggtcct gaatttgatg gtcatttagt
     1201 tgattttgat caagcaatga gaagacagtc tatgtacaag actcaagagg gaagagctat
     1261 gctaaaactt gaagaaggcg atagtcatca tcatagtaat tgtggatgtg gaggtaacaa
     1321 ataatggatg ctaaaaaagt aaaagtacca gttagagaac aagaacctgc agtgagagca
     1381 acaaattttg atgaggtatg cttagggtat aataaagaag aagctatggc agaagctaat
     1441 agatgtttag cttgtaaaaa accaaaatgt gtgggtggat gtccagtagg aatcgacata
     1501 ccagggttta taacaaaaat taaagaagat gatatagaag gtgctgctaa agtaatagct
     1561 aagagcagtt cattaccagc tgtttgtggt agagtatgcc cacaagaaag tcaatgtgaa
     1621 ggtgtatgta tacttggaat aaaatcagat gctgtatcaa taggtaaatt ggaaagattt
     1681 gtagcagatt ggtcaaaaga aaatgacata aatttatctg atacagagcc taagaaaaat
     1741 caaaaagtag cagtaatagg aagtggtcca gcaggtctag cttgtgctgg tgatttagct
     1801 aaaaaaggct atgatgtaac aatctttgaa gcaatgcatg agccaggtgg agttttaact
     1861 tacggaatac ctgagtttag acttccaaaa caagctgttg ttcaacctga aatagacaat
     1921 ataagaaaat taggtgtaaa aatagaaact aatgtaattg ttggtaaaac aattacagta
     1981 gatgaactta tagaagatga aggatttgaa gctatattca taggttcagg agctggtctt
     2041 ccaatgttta tgaatatacc aggggaaaat gcaaatggag tattttctgc aaatgagttt
     2101 ttaactagag taaacttaat gaaggcttat agagatgatt atgatacacc tattagttct
     2161 ggtaaaaaag ttgctgtagt aggtggtgga aatgttgcta tggacgctgc tagaactgca
     2221 ttaagattag gttcagaatc atatatagtt tatagaagaa gtgaaaaaga gcttccagca
     2281 agagctgaag aagttcatca tgcaaaagaa gaaggcatta tatttaatac attaacaaat
     2341 cctaaggaaa ttttagtaga tgaaaatgga tatgttaaag gtatggtttg tataagaatg
     2401 gaattaggag agccagatga ttctggaaga agaagaccta tagaaataga aggttctgaa
     2461 tttgtacttg atgtagacac agttataatg tcacttggaa caagcccaaa tccactaata
     2521 tcttctacaa caaagagtct tgatataaat aagaagagat gcttaataac agatgaaaat
     2581 ggtcagactt ctaaagaggg tgtatttgca ggtggagatg ctgttactgg agcagcaacg
     2641 gtaatatctg caatgggtgc tggtaaaaca gcagcagcat caatagatga atatttaaaa
     2701 gcaaaagtta atgcttaatt tgtaaattaa agagagggtg tctcaaaatg aactttttag
     2761 ttcatgagac actctttttg tacaaaatca aatatgtttt aatcatttca acaatgaaaa
     2821 tttcattcct gtagaaagtc taacttttag gtcttagtac aatctctatt ttgatgtagc
     2881 cactttttta gatggtttaa taatttatca gttattattg taatatttga tactaagtaa
     2941 cataactttg tctaactatg ataaaatagt tatacaataa aggtcttgta aggagtgaat
     3001 aatgtgtggc taataaaatc agatttgtca aatctaacat taaataatag aaaaataaat
     3061 tgtgtaatta atggtatttt aatatgaaaa aaagagaaaa agtatttgat gggctagttt
     3121 ttaagcatat attaatctta ttaatactat tagttttgat tgatttaaca agtaccatca
     3181 tatatgcaag taactctatg gaaattactt ctagaaatat gattgaggca tcaaaaagag
     3241 aacttgaaaa ctatttagaa gtaaacatat ctttattaaa agctcttagt caagatgata
     3301 gattttctaa tggtgaaaca tcactaattg aaaagggaaa attattaagt ccatatcaaa
     3361 aggaatataa tctttttatg attggtataa cagatacaaa aggaaatgct tcaagtacat
     3421 atagggaaaa tgttaactca ataaaagata agcctagttt tgagaaagca attaaaacaa
     3481 agcaagtagt agtttcagat attgaagtca gtaatgtaac aggtgacaaa gtatttatca
     3541 tatatgtacc aattgtaaaa aataatgaga tgattgggac catttttgct tctttttatt
     3601 ttcaagatgt aaataattta ataagtagaa gcaattttga tgattctatt aaatttctaa
     3661 tgatagataa agattatact attatttctc atccaaacaa aaaatatgta aatgataaaa
     3721 gtaagatgct tgatttagaa gggaatatta taggaaccac taaaagtgaa atcttaaaaa
     3781 atataaataa aaaatgtcaa ggtgattttt tatcttggga taattggaga ttatataatg
     3841 taaaatatac gaacataaag tggactaatt ggactttagt atcaaaatgt aatatattta
     3901 agaactttaa aaatctaata gttaatttta tgataaagtt gtatttttat atagtaatat
     3961 ttatgatatt gtggaaatta agtaatgcta aattaataga acaacttaaa aaattggctt
     4021 attatgattc tttaagtgga ataaaaaata aagaaaagtt tagaaaagat tctatgtata
     4081 ttttaaagaa ttattatcaa gataattttt acttagtaca attggatgtc aataaattta
     4141 aatatataaa tgagatgttt ggatatgctg aagggaataa gatattaatt catatatcac
     4201 aggttttaaa taataataca aataaatatg aaatttgtgc taggatggat aatgaccatt
     4261 ttatattgtt gattgcttgt aacactgaag atgaactttt aaatagatta tctaaaataa
     4321 ataaagaaat ttgtaactta aatactacta actcatctaa gtataaaatt gttatgtcaa
     4381 gtggaatata taagattact aaaaaggatg atattaaaaa gattgacttg ttaattgata
     4441 gagcaaatat tgcagcaaaa agtaaaaagg aaaaatatga acattcatat tcatttttta
     4501 atgaagatac aagaaatcga ttgtacaagg aaaaacgatt ggaagataat atgaataaag
     4561 ctttagaaaa aggtgaattt atagtatatt atcaacctaa gtatagttta gatgatgtaa
     4621 atgaaattga aggagcagaa gccttgataa gatggaatag tccagaattt gggtttattt
     4681 cacctataga ttttgtacct ttatttgaaa agaatggttt tattgtaaat attgatatgt
     4741 tcgtgtttga agaagtatgc aaaacattaa acaagtggat aaataaaggg tatactcctg
     4801 taccaatctc tgtaaatatg tctagagttc atttatatag ggataatttt atagaaaata
     4861 taactgattt gataagtaaa tacaatatat ctcctgagtt tattgagctt gaactaacag
     4921 aaagtgttgt gtttgataat ttaaatatat tgattgatat aatgaaaaag attaaagaga
     4981 taggattcct tatatcaatg gatgattttg gttcgggata ttcatcttta aatctgttaa
     5041 aagacctttc ttttgatatt ttaaaattag atagaggatt tttaatcgaa acaacagata
     5101 caaaacgtgg aaaaattatt atttctaaga ttgtggaaat ggcaaaagcg attgatatta
     5161 aagtaatctg tgagggcgta gaaacttatg aacaagtaga gttcttgaaa gagataggtt
     5221 gtgataaggt tcaaggatac ttatttgcta aacctatggt attagatgaa tttgaaaaac
     5281 acttaaactt taaatttgat taatcattaa taattattag actataagat accctaacaa
     5341 cttacttaca aatatgtaag ttaattgtta gggtattttt atggttaaag tagtatattc
     5401 acgatattat ggtattgtag taaaaataaa aaattatgga gaatataaaa tgaacatatt
     5461 gagtattaga aatatatcaa aaacatattg tggaaatatt ccatttaaag cattagataa
     5521 ggttagtcta aatatagaaa agggagaatt tgtgtctgtt atgggaccat ctggaagtgg
     5581 taaatctact cttttaaata taatatctac agttgataga cagagtgaag gtgaggttgt
     5641 attagatgga tatgatgtaa gtaaattgaa aggagaaaaa cttgctgaat ttagaaggaa
     5701 acaacttggt tttgtatttc aggattttaa tttgattgac actttaactg ttggcgaaaa
     5761 tattatgttg ccacttacac tagagggggc aagtatcaaa gatatgaata tacaaactaa
     5821 aagtatatct aaatttttag gaatagataa aattttagat agaaaaacct atgaaatttc
     5881 aggaggtcaa gctcaaaggt gtgctattgc tagagctatt ataaataaac ctgccatact
     5941 tcttgcagat gagccaactg gaaatcttga ttcaaaatct actgatgatg ttttgaaatt
     6001 atttactagg ataaacaaag aacaaaaggt aacaacactt atggtaactc atgaagcata
     6061 tagtgcaagt tattcagata gagtaatttt tataaaagat ggttgtatat atacagaaat
     6121 aaaaaaatct gaaagcagta attctttcta ttctgatata ctagctgttt tgtctcaaat
     6181 aggaggtgta agatagtgga ttttagaaag tttgcttata ataatatagt tagaaatttc
     6241 agggcatatt tagcatattt tttaagttct gttttttcta taatgatatt ttttgttttt
     6301 gcagtgtcta tgttccatcc aattataaca aaatctggaa tgcagagtgg ttctactgca
     6361 tttatggctc ttatgacttc agaattaata atattcggtt ttagtctact ttttatattg
     6421 tactctttag gaaatttctt aaaatataga ttgaaagatt ttggagtatt gatgataatt
     6481 ggaatgagta acagacaact gaaaaaattg atattaattg aaaatttgat aataggattt
     6541 ttagcagtga tgttaggaat attacttggt ttatcaattt caaaattgtt tttattgtat
     6601 ttaagcaaac tgttttatat gaatttaact gaattttatt ttccagtaaa agcaatgcta
     6661 ttgactattg tatcatttat gattttattt ttgataacag gaccaatgag cttaaaatta
     6721 ttgagtaaaa agagcatttt agagctttta gtaggtacaa aaaagcctaa aaaagagata
     6781 aaatcttcaa agctatttgg aataattggt gtaatatgtc ttatattagg atatgctatg
     6841 atactatttg gcaataagtt aaaaataaat ggaggtatgt atacaacagc actattaatt
     6901 actttgggga tatttttatt tttttctcaa tttactattt tgatattaaa gtatttaaaa
     6961 aataaagaaa aattttataa gaacaaagta aatatgttac ttataagtaa tttgatatat
     7021 aaattaaagg ataatacacg attgttattt ttaataacaa tacttttatc ggctacttta
     7081 gtagcattta caacaacttc aacacttgta agttctcaag gagaagcttc taaaaataat
     7141 ttcccaatgg tttactcata tttttcagag cataataatg aaaaagaata tgaagaacta
     7201 caacaaatta gagaagcaat caaaggatat gattataagg agttaagttt tcctgtactt
     7261 aaatataata gggaagtctt actaagtgta aagaattata acaaattatc aaaggaattg
     7321 ggattagata aaattagttc aaagttagaa aaatatgaag ggattataat tcctagtagc
     7381 aattcgcaag aacatataaa ttctttaaaa caattaaaaa attatagtat aaaaaattta
     7441 aatatagaag taaaaaaatc aaaaaataaa ataatttttc ctacaggact gtttagtaaa
     7501 gttgtggtta taagtgatga cttatacaat gaagtaaaag gtgaattttc aaaaattaat
     7561 tttcatggat ttgattataa aaactggcaa agcagtgcaa agataactga aaatttaaaa
     7621 gaaaaacatt ttaatttgga tagagaatat aacaggtcat attttttaac attaccagat
     7681 atgtatttag tagagttaca acaaagtaaa attcttcaat ttatgggtgt ttttatagga
     7741 gtgatattat ttatagcagt ttttagtttt ttatacttca gattatatac agacgagata
     7801 gaagataatg taaagtacaa aaaactatca aaaataggtc tatcttttaa aaatatgaat
     7861 aagattgtta gtatagagat aggtacattg ttttttatac cgtattttat agcaattata
     7921 aatagcataa tttctttact gtttttaaat caagtattaa ataatagttt taagttagaa
     7981 aatttgggta tattactact gatatcatct atatattcac tttattttta cttattaaaa
     8041 aaaaattata ctagaaaagt ttggtttttt gattaaagtg gtatataata gatatataaa
     8101 ttaatattta aaaagtagtt aatattaggg gagggcattt gcacctccct tgtaatatgt
     8161 ggaaaattga atattagaag aaggaggaga cttgatggaa aatcaacaat tattaggaac
     8221 agaacgaatt agtaaattac tactaaaata ttctatacca gctataatag gtatgttggt
     8281 aaatagttta tataatgtag tagatagaat ttttattgga aatataccag gggttggacc
     8341 acttgcaata acaggtcttg gtgtaacaat gccaataatg acaataatac ttgcatttgg
     8401 gatgttgata ggtataggaa ctactactac catatcaata aaacttgggc aaggtaaagt
     8461 agaagaggca agaaaactta taggaaatgc aatgacgtta tctgtaataa caggaattat
     8521 cataatgata cttggaatat tatttgcaaa taaaatactt acattgtttg gagcaagtga
     8581 aaatacttta atatatgcaa aatcatatat caatattata ttattaggta cagtagtaaa
     8641 tcttctttcc ttttctttaa accactcaat aagagctgat ggtagtccta aaatttcagc
     8701 aggaataatg atagtaggat gtttaactaa tatagtttta gactggatat taatatttgg
     8761 attcaatttg ggaatacaag gagctgcaat tgctacagta acttctcagg ctcttacagc
     8821 tattttaact atagggtatt atataagtgg aaaatcaaac ttacgattca gtaaatctaa
     8881 tctaaaatta gataaaaagc taataaaagc agtgtttgca ataggtatgt cgccatttgc
     8941 tatgcaactt gcagcaagtt tagttcaagt aatatcaaat attgcactta aaactcatgg
     9001 tggagattta gctatagggg ctatggctac tatttcttct attgcaatgg tatttttgat
     9061 gcctatcttt ggaataaatc aaggagcgca acctattata ggtttcaatt atggagctga
     9121 aaaatatgat agggttaaaa aagcatattt aggttcatta gtagtagcta ctataatttt
     9181 atgtatgggt atggtagtag ttatgctttt cccagaagct attataggta tatttaataa
     9241 agaccctgaa cttatgaata tatctgttaa tggattaaga atatacttac ttatgttgcc
     9301 aattgtaggc ttatcagtta caggaacaaa ctttatacaa tctataggaa aagcaaaaat
     9361 ggctatgtta ttgagccttt taagacaagt aattttattg ataccagcag tattaattct
     9421 tcctacattc ttaggtttac agggtgtatg gacagctcaa ccagtgtctg attttatagc
     9481 tacagtaatt acaggtatag ttgtatttag agaattaaaa agatatactc ctaaaactga
     9541 aaaattaaat gaaaatgaaa gactaaacga gataactact gagtaaaaat ataaattcag
     9601 ataattgagc aagaaattgc aaaaaatacg attatatgat aaaataaaac cgctgtcaag
     9661 gataagagaa attctaatta tggagtgatt ttatggaatt tacaaagaaa agcaaattaa
     9721 aaaatatgta tgtaaacatg aatgtagcta gaatgttgtc taagataaat gagtataagg
     9781 gtagacaact gctttacaaa aaacaaccaa aagaaatttt agaaaactta gaaaaaaaat
     9841 ctttagtaga ttgttctgaa tctacataca ttggaaatca aagagatagt agtaatttta
     9901 atctagaaaa gttgataagt aatgaagtta cacctagaag tagagaggaa ttgagtattg
     9961 ttgaatacag agatgtggta aaaactatta acagtgctta tgagagtatt cccatcagtt
    10021 cacaaacaat tcttgagctt catggatact tatataaatt ttcatctact agaggaggaa
    10081 gttataagtc agataatgat tttattgaac acaatttaaa acctagcgaa tttataagta
    10141 ctgattcaag tgtcaataaa gttgaaaaag ctgtagaaga aatatgtgaa gcttataata
    10201 cattgataga ggaagatgaa attgatatat taatattaat ttctgcattt gtgttagatt
    10261 tcatattgat acatccattc aaagaaggta atataaaaat ggcgagagta cttatcctat
    10321 tgttactaaa taaaaatggg tatgaagttg gaagatatat aagtttagga aagatatttg
    10381 atgatagttc atatgaatat tatagtaatt taaattattt gaaagcctca ataggtagtg
    10441 aaaaagcaga tatgaatgca tggattgagt attttttaga gacgatatta actgcatatg
    10501 agaagctgga tgatagttta aatatatctg ataagaaaag acaaacaaaa actagtagaa
    10561 tagagaaaat aataaattct acccttggat attttacaaa agaagatata agagatttat
    10621 gtcctgacat tccagaacct actataaata gagtttttaa taatctaaga aaacaagata
    10681 agatagaagt tgttgcaaga ggaagaagtg caaaatggaa gaaaaaatat taaaaaatgt
    10741 ttagataact aaaatggtat agtgttttac actataccat ttttaatgtc attagcatga
    10801 gcaataattt aacaacttaa gcaatatcaa ttttatttat tgattatttt tgaactgaaa
    10861 aatggcgtta tatggtatac ctcagtggta attaattttg gatgagaaga tataatatta
    10921 cagaatatat taggagtata tgtagaaaaa atataataaa agtgtgaggc ttagtaatta
    10981 acaaattatg tggcttcaca cttttttata aaataaagat acttagcaga ataatatttt
    11041 agttgatatg tttataagat ggtacttgtt tgggtaaaag tataaatagt aaaaaagtag
    11101 aagtaatgtg tataaaaaca taagttacat tctgtaataa tagttatttt ataattcaac
    11161 aaaagaatag aatgggtata tttgtgaaat aataatataa aataatctta ggagtgagct
    11221 tatgaagaaa aaattattat atataaatgt aaattcaaaa cctgaagact tatcttcaag
    11281 taaaactgta gcaagaaaat ttataaataa atttatggaa aaaaataaag attttgaggt
    11341 tgaagagata gacctttata aagaacatat accaagactt gagtatcagt actttgaaaa
    11401 aagaaatagc atagttagtg aagaaaatgc taaaaattta gacgataagg atagaaaaga
    11461 gcttacaaag attagaaatc tttgtgacca atttgtgaat gcaagtgttt atgtaatagc
    11521 agcacctatg tggagtttat cttttccagc accacttaaa gagtatatag attgtataat
    11581 tcaagatgga aaaactatat cttttgaagg caatgataaa ccacaaggaa ttttaaatga
    11641 tattgataga agtatggtat atatacaatc ttctggtgga cacataccat gggtgttgaa
    11701 gccagttatg aataaagggt taaattatgt ggaaagtatt atgaaattta taggaattaa
    11761 aaaatttgat gaattgttag tagatggaac tggaactagt gaagaagaaa gacaagctgc
    11821 aatagaaaaa gcatctgaaa aaatagatgg tataatagat gggatgaaat tttaattata
    11881 atattttatt aaaaatataa aggaaaaacc tcttttaatg tagaaactta tattgaagga
    11941 ggcgagaatc atgcgagaag aaaaaagtaa tgaaaagtat gattgttatt ggtgtaatca
    12001 agagaataat ttctgtgtag aaataaaaga taatatagtc atgatagatg atggcactgg
    12061 tacgttaaaa caagccgttt tcatagggta taaacaaatc caaattaatt taaactgttc
    12121 acattgtcaa aacttaaata gaataaaatt aaatttgtag aattttaaaa tggaaattat
    12181 tgaaggaatt aaaaatagaa agtgttaata tttagactga aaattatatt ttatacaata
    12241 aaagtttatt taaataacat tgtattttaa tatttatttt cagtcttact ttattaaaat
    12301 tattttttgg ttatgtctgg aaaatatctg tctactaatt tttctgaaat attttttaat
    12361 tggtcagcca ttgaagtcag acttaataag gctatcaata aatcatcttt attttctgga
    12421 tttatactaa tattttcaaa attagactct ataaagtccg gtatattctt tctttgattt
    12481 tcttttatta acatgaattt ttcgtaacat gaaactaaat ctttttcact gaaattatcc
    12541 ttttcataca caccatgtaa gattctttta atttcttgta ttgtaagtgt atttttcata
    12601 gaataaataa ttatcatctg taaaatttgt tctttagtat acttttttcc cttaactggt
    12661 ttgattaatc cctctttgct gtaattattt atcatggttt tagtaagaat tttatcactt
    12721 tcaaatcttt tattagcaga aagcttattg tcaattagag aaataatttg atccatatat
    12781 aagtcaatag atggaatatc gtttgaagtt atatctgcat tatttagtgt ttctagtatt
    12841 atagtattaa gttcattatt catcatatgt tacctccata atatatataa tacactaaat
    12901 tagaaagtaa aacaatatta aggcttgtaa aaaaaacata aagtggtata attaaatata
    12961 taatatagta atcaaaacta tatttatgaa tctgattttt aaaatacata attgtaggag
    13021 gacgaaatgt atcaattttt tttaaagggt agagacccaa taagcagttt aactcatttt
    13081 ataggtgctt gtttatctct tttagcaact ataattttag tttttcaatc tgttacatta
    13141 caggaaactt ctctcttgat gatagtatct gtatctgtat ttggactttc actaattgct
    13201 ttatatagtg caagttcgta ttatcatttt ttaaagggga caccagaaca agaattgttt
    13261 tttagaaaag tagaccatgc aatgatttac gtattgattg ctggctctta tacaccaata
    13321 tgtctgaatt ttatggaaaa aaaagaaggc ataatatttg ttacagcaat atggatagtt
    13381 gcatttattg gcataataat aaaaatattt tggatggatg cacctagatg gttatctacc
    13441 agtatatatt tacttatggg gtgggcaatt gtttttgata taaatgcatt caattcaatt
    13501 cctaaggatt gccttagact attaattatg gaaggtgtat cttactctat aggtgcgatt
    13561 atttatataa ttaaaaagcc taatataagt cctgagtttg gatttcatga aatatttcat
    13621 atttttatta tgataggttc tttatttcac tttttagcag ttttattgta tgttttatag
    13681 ttttaaaaga tttgattaat tgatactaaa attctacaat gaataaaatg gaactgcctt
    13741 atatagatta tatcttagac aataagacag ttccttatta taaatattaa attctactta
    13801 taataaaatt ttgataaaaa tagtccattc aaaatgccta ttccataatt cctttaatgt
    13861 acttttcatt tacgacatat agtttgaatt tatgtactat aattatatcc tctaaattct
    13921 ctgaaacact aacaattctg acacatttgt ttctaatttc tacaggtaaa tctaaatcat
    13981 ttgttaaatt cacatagtca tcatatttat acataaaatc atccctttac attaagatat
    14041 a
//
LOCUS       DAMKNB010000089        13401 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.095, whole genome shotgun sequence.
ACCESSION   DAMKNB010000089 DAMKNB010000000
VERSION     DAMKNB010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 13401)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13401)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13401
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.095"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            170..2029
                     /locus_tag="PC494_003012"
     CDS             170..2029
                     /locus_tag="PC494_003012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HDF3913495.1"
                     /translation="MKRFLRRIILVLFILLIFISFISIKLIHNVGDYGKLINYVGIVR
                     GASQRLTKLEMNHQPNDELIEYIDEILQELITGHGDYGLVITDCNEYNEDLLLLEKKW
                     EDLNIEIKKVRMKEQNNQLLSISEEFFSLANDTVFKIENFSKEKSNYLMTLIIIISII
                     GILACIILILQYSKKMVRLEKLNVDLKNIAYKDELTGVNTIEKFKLDANQNICIHKDK
                     KFAVFYIDFENFKYINDIFGYDYGDMILKRYANLMMNDIGKYEIFAREIADRFVALRC
                     YVDKEDLVVRQRDVDNELINITNEIKNKHSITVVSGICCIEDVNEKLSIDGLINRANF
                     AQKTVKNKPGTNYAFYNDSIRKKMIEENTIKSRIHEAIEKREFIVYLQPKVNLHSQKI
                     NCAEALVRWLTPDKGIISPAIFIPVLEKNFFIALVDKYVFEEVCKWIRKRLDENKPFV
                     QISVNVSRIQFYNTKFVETYSNIQNKYRIPKNTIEIEFTESVAFENQKHLLEIIHDLH
                     ENGFTCSLDDFGKGYSSLSVLKDLPFDVLKLDSMFFKASLDKDKEKIVIKNIVHMLKE
                     LNITTVAEGIECKEQVEFLRDIGCDLVQGFVFYKPMPILEFEKILDKEFVYNS"
     gene            complement(2321..2920)
                     /locus_tag="PC494_003013"
     CDS             complement(2321..2920)
                     /locus_tag="PC494_003013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerD family protein"
                     /protein_id="HDF3913496.1"
                     /translation="MAIELKKGQKINLTKKENSDLGEILVNLNWNQKVQKKGFFGSLR
                     SSNIDLDLGCLFEMKNGVKGAVQALGNAFGSLDNPPFAQLDGDDRTGSNTQGENLRIN
                     GNKIKDIKRILIYAFIYEGVANWSEADGIVTIKQKQDSDLVVKLDEHKNGYNMCSIAL
                     IENVNDETFSVEKVVKYFKGHREMDTEFHWGLKWVAGRK"
     gene            complement(3023..3820)
                     /locus_tag="PC494_003014"
     CDS             complement(3023..3820)
                     /locus_tag="PC494_003014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HDF3913497.1"
                     /translation="MKFKKLLCLLLCLVLTLAVVGCSKAKDDKKIVVGATLVPGGELL
                     EELKPLIKEKGYTLEVKNFDDYILPNEALNNGEIDANLFQHEPYLKEAVKAKGYKIMA
                     GKKLYVCPAILYSYKIKSVDEFKKGDTIAISNNPSSCSKNLRYLESIGLLTLPKGDGL
                     VSPKDIIENPKGIQFKELDIAQIPSSLPDVTAAFIDTTYAVPAGLDAKKNGIYTAPIN
                     DEYANLLAFRTEDKDSEKIKVLQDVLTSDKARSLIEEKYKGIVIPTF"
     regulatory      complement(3933..4039)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00162"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="SAM riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF00162"
     gene            complement(4131..5117)
                     /locus_tag="PC494_003015"
     CDS             complement(4131..5117)
                     /locus_tag="PC494_003015"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HDF3913498.1"
                     /translation="MLLIYNEKTNPYFNLAMEEYLLKNFDEDLFILWRNEPSIIVGKN
                     QNTLSEINLEYIKEYSIPVVRRQSGGGAVFHDLGNINFTFIACNNNNFSDFRRFTQPI
                     IDLLKTLDVNAEFSGRNDLLIDGKKFSGNAQYNYKNKVMHHGTLLFSSEINDLSKALK
                     VKPIKFEGKGIKSVKSRVTNISEHLHSKMDILEFKDAIMDYLSKTNTDNTNYCLSEHD
                     IKQIEKLTKSKYETWDWNFGNSPKYTLSNELKYSGGNVEFNLNVDKGIITSIKFFGDF
                     FGKCDVAFVENKLIGIRHEENALRNTLDSIEINDYFLGADTDILVSGILGVK"
     gene            5601..7331
                     /locus_tag="PC494_003016"
     CDS             5601..7331
                     /locus_tag="PC494_003016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC family protein"
                     /protein_id="HDF3913499.1"
                     /translation="MRNKKINIIFLTTIMFIMSTVMVFAEEDIDTIALANAEKFGILT
                     LIPPLVAIILAFITKNVIISLLIGILSGSFIIKASGINVFATFIQAFLDLVDRALVSL
                     ADPWNAGIILQVLAIGGVINLVAKMGGAKAIAEALAKRAKSAKGTQLITWFLGLLVFF
                     DDYANSLIVGPMMRPVADKMKISREKLAFIIDATAAPVAGLAIISTWIGLEVGLIHDA
                     FESISIDVDAFGIFLNTIPFRFYNILILAFIVISALLLKEFGPMRKAEIKSRSRKISI
                     DLDEGVEELDDLAPKNGVKLSVWNAIIPIGTLIIVALASFYYSGYTSIMGGDDKALIQ
                     LFTNSPYSFEAIKEAFSASDASRALFQSALVASLVAIIMAVVKKIFTISEAIDVWIDG
                     MKSLVITGVILILAWSLSSVIKELGTAKFLIHLLSGSLPPFLLPSLIFGLGAIISFAT
                     GTAYGTMGILMPLAIPLAYSLNPDMSYVIVSTSAVLTGAIFGDHCSPISDTTILSSMG
                     AGCNHIDHVNTQMPYAIFTAVITIVFGYIPAGLGLPIYIVLPVAIAAIFVGIQIIGKK
                     VDEAEIELVE"
     gene            7441..7521
                     /locus_tag="PC494_003017"
     tRNA            7441..7521
                     /locus_tag="PC494_003017"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:7475..7477,aa:Leu,seq:tag)
     gene            7856..8371
                     /locus_tag="PC494_003018"
     CDS             7856..8371
                     /locus_tag="PC494_003018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HXXEE domain-containing protein"
                     /protein_id="HDF3913500.1"
                     /translation="MEKYIWLFPLLFIFHDMEEIIGFGIWLKKNKSMLDKKYPFISKV
                     YENYSTEGMAFAVFEEFILCIIFCILTVITENQYVYLLWLGSFIAYTLHLVIHIGQSI
                     IIRKYIPSLITSIICLPISIWCISKSIYIVDCEMSTTILYSIIGIIIVALNLKFAQSL
                     IGKFTKWMSNI"
     regulatory      8863..8967
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            9177..11651
                     /gene="gcvPA"
                     /locus_tag="PC494_003019"
     CDS             9177..11651
                     /gene="gcvPA"
                     /locus_tag="PC494_003019"
                     /EC_number="1.4.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminomethyl-transferring glycine dehydrogenase
                     subunit GcvPA"
                     /protein_id="HDF3913501.1"
                     /translation="MNELKRVSLYNIHKELGAKLVEFAGWEMPLEYEGINKEHEKVRK
                     SAGIFDVSHMGEVQIKGAESEKFIQNLVTNDISTLKINDIIYTPMCYENGGVVDDLLI
                     YKFGEEDYLLVINAGNIDKDVAWIIKQSEGYNVDIKNISSEVSQLAIQGPKAEEILQK
                     ITDIDLNSIKFYKSIPSTKVCGCPCLVSRTGYTGEDGFEIYCKNKYVEIIWNEVLKVG
                     GEDICPAGLGCRDTLRFEAALPLYGHEINEHISPIEGGLSIFVKTNKESFIGKSILSK
                     EKESGAKRKLVGFEMQGKGMPRNGYDIRIGDKTVGFVTTGCASPTTGKILGMGIIDSE
                     YAKVGNEIGIAIRKKVVPAVIVKKPFYKKQYKKDNIILNKENKFSYIPATSEDKSKML
                     KVVGLNSVDELFSDIPEEVKLKRDLNLEIGKSELEVSKIVKRLSEENLSLEDLTCFLG
                     AGAYDHYIPSIIKHITSRSEFYTAYTPYQAEISQGTLQVVFEFQSMIAEITGMEIANA
                     SMYDGATAAIEACIMAMNQTRKSKIVVSKTIHPETLSVLRTYLQYKDCEIVEIDFCNE
                     YGTTDIEKLKASVDKDTACVLIQTPNFFGIIEEMEEIEKITHENKAMLIMSVDPISLG
                     VLKTPGEIGADIVVGEAQSLGNPLNFGGPYVGFLASKSKYTRKMPGRIVGQSLDVEGK
                     IAYVLTLQTREQHVRREKATSNICSNQALNALVASIYMATMGKEGFKEVGMQSMKKAH
                     YTYNKLVQTGKYKPIFKGKFFKEFAVQGNLNIETINDKLLEENILGGYNLEYNYPELK
                     NSTLLCVTEKRSKEEIDKLVGIMEGL"
     gene            11651..13108
                     /gene="gcvPB"
                     /locus_tag="PC494_003020"
     CDS             11651..13108
                     /gene="gcvPB"
                     /locus_tag="PC494_003020"
                     /EC_number="1.4.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminomethyl-transferring glycine dehydrogenase
                     subunit GcvPB"
                     /protein_id="HDF3913502.1"
                     /translation="MKEYNSLLIDISKKGRKAYSLPKLDIDDIKIEDMIDPDMARQSE
                     LNLPEVGELELVRHYTLLSNKNFGVDTGFYPLGSCTMKYNPKINEDMAALPNFTGMHP
                     YQSSDTAQGSLSLMYDLSRRLAEITGMDEVTLQPSAGSHGEFTGLMIIKAYHENRGDH
                     KRTKVIIPDSAHGTNPASAAMANFDVIQIASDKNGAVDINVLKEVLNDEVAALMLTNP
                     STLGLFEKNIKEIATLVHEAGGLLYYDGANMNAIMGITRPGDMGFDVVHLNLHKTFST
                     PHGGGGPGAGPVGVKKELVPFLPIPVIERKEDKYVLNYDREKSIGKIKNFYGNFGVLV
                     RAYTYILTMGRDGLKEASEMAVLNANYIKESIKDDYILPIDTLCKHEFVLGGLPRGEA
                     NIKTIDIAKRLLDYGYHPPTMYFPLIINEALMIEPTESESIETLDSFIEAMKSVAKEA
                     KEEPELLKTAPHNTLVKRVDDARAVKKPILTWSQR"
BASE COUNT         5035 a         1588 c         2200 g         4578 t
ORIGIN      
        1 aaaaaatttt tgtatatata aaggactcta aagatgaact atgtaaaaca aggtttatat
       61 attctaattg tatagaaaaa tttattgtaa acgcatgtat attattagaa aaaatagttt
      121 ggaggtattc aataaacata aaaaacaata taggggataa aggtgtttta tgaagagatt
      181 tttgaggaga attatcttag ttttatttat tttgttgatt tttataagtt ttatttctat
      241 taaattaatt cataatgttg gagattatgg aaaattgatt aattatgttg ggattgttcg
      301 tggagctagc caacgtctaa ctaaactaga gatgaatcat caaccaaatg atgaattaat
      361 agaatatatt gatgaaatcc tacaggagtt gattacaggg catggagatt atggtttagt
      421 aatcactgat tgtaatgaat acaatgagga cttactttta ttagaaaaaa agtgggaaga
      481 tttaaatatt gaaattaaaa aagtaagaat gaaagaacag aataaccagt tattaagtat
      541 aagtgaagag tttttttctc ttgcaaatga tacagtgttt aaaatagaaa acttttctaa
      601 agaaaaaagt aattacttaa tgactttaat aataattata tctattatag gtatattagc
      661 atgtatcata ttgattttac aatatagtaa aaaaatggtt agactggaaa aattaaatgt
      721 agatttaaaa aatattgcat ataaagatga actaacagga gtaaatacta tagaaaaatt
      781 taaattggat gcaaatcaaa atatttgtat acataaggat aagaaatttg ctgtattcta
      841 tattgatttt gaaaacttta aatacattaa tgatatattt ggatatgatt atggtgacat
      901 gatactgaaa agatatgcta atcttatgat gaatgacata gggaaatatg aaatatttgc
      961 aagagaaatt gcagatagat ttgttgcgtt aagatgctat gtagataagg aagatttagt
     1021 ggtaagacaa cgagatgtag acaatgaact aattaatata acaaatgaaa ttaaaaataa
     1081 acatagtatt actgttgtta gtggaatttg ttgtattgaa gatgtaaatg aaaaattaag
     1141 tatagatggt ttaataaata gagcaaattt tgcacaaaaa actgttaaga ataaaccagg
     1201 tactaattat gctttttata atgacagtat tcgtaaaaaa atgattgaag aaaatactat
     1261 caaaagtaga atacatgaag ctattgaaaa aagagaattt atagtttatt tacagcctaa
     1321 agttaattta catagtcaaa aaataaattg tgcagaagct ttagttcgtt ggcttactcc
     1381 ggataaaggt attatatctc cagcaatatt tattccagta cttgagaaga atttttttat
     1441 tgccttagta gataagtatg tttttgagga ggtttgtaaa tggattagaa agaggttaga
     1501 tgaaaataaa ccttttgttc agatatcagt taatgtttca agaatacaat tttataacac
     1561 taaatttgta gaaacttatt ccaatataca aaataaatac aggataccta aaaatactat
     1621 agaaattgaa tttacagaga gtgttgcttt tgagaatcaa aaacatcttt tggaaattat
     1681 acatgatttg catgaaaatg gatttacttg ttctttagat gattttggaa aaggttattc
     1741 gtctttaagt gttttaaaag atttaccatt tgatgtttta aagcttgatt ctatgttttt
     1801 caaggctagt ttagataaag ataaagagaa aatagtaata aaaaatattg tacatatgtt
     1861 aaaagaactt aatatcacaa ctgttgctga aggcattgaa tgcaaggaac aagttgaatt
     1921 tcttagggat attgggtgtg atttagttca gggatttgta ttttataaac caatgccaat
     1981 attagaattt gaaaaaatat tggataaaga gtttgtttat aatagctaaa atgtacttta
     2041 taaaatatga actaattaag taaaattatt ttgtactgaa taaattttta ctttatttac
     2101 agaataatga ttatttacag aaaagcgcga aaagtgtatt cctttaagtg tgggatggat
     2161 agcacaaata ggggagaaaa aatattggcc atataagaat gcataataat ataaatattt
     2221 gaaaggtcag cattatataa aaattaaaaa gaaaataaat aatttttcta taaaaaagag
     2281 actatgagaa aatttactca tagtctccta aataatgtat ttattttctt cctgcaaccc
     2341 attttaatcc ccaatgaaat tcagtatcca tttctctatg acctttgaag tatttaacta
     2401 ctttttcaac actgaatgtc tcatcattta cattttctat caatgctatt gaacacatat
     2461 tatagccatt tttatgttca tcaagtttga caactaagtc tgaatcttgt ttttgtttga
     2521 ttgttacaat tccatcagct tcagaccagt tagctacacc ttcgtatata aaagcataaa
     2581 taagtattct ttttatatct tttattttat taccatttat tcttaaattt tctccttgtg
     2641 tattacttcc tgttctgtca tctccatcta attgagcaaa aggtggattg tctaaactac
     2701 caaaggcatt tcctaatgct tgaacagcac cttttacacc atttttcatc tcaaataggc
     2761 aacccaaatc taaatctata ttactgcttc ttaaagagcc aaaaaaaccc tttttttgta
     2821 ctttttgatt ccaatttaaa ttaactaaga tttcacctaa atcgctattt tccttttttg
     2881 taaggtttat tttttgtccc ttttttaatt ctatagccat agtaatcttc ctccacaaac
     2941 atagatttat ttaaatggta gcacttaata agtcaatatt caacaagatt agaataataa
     3001 tattaaaatt atattaaata tactaaaaag taggaatcac aatacctttg tatttttctt
     3061 caattaagct tcttgcttta tctgatgtaa gaacatcttg tagaacttta atcttttcac
     3121 tgtctttatc ttcagttcta aatgctaaaa gatttgcata ctcgtcattt ataggagctg
     3181 tataaattcc gtttttcttg gcatcaagac cagcaggtac agcataagta gtatctataa
     3241 atgcagcagt cacatctgga agagaagatg gaatttgagc aatatctaac tctttgaatt
     3301 gtattccctt tggattttct attatgtcct taggactaac taatccatcc cctttaggta
     3361 acgttaaaag tccaatactt tcaaggtatc taaggttctt agaacaagaa gatgggttat
     3421 tgcttattgc aattgtatct ccttttttaa attcatcaac agattttatc ttataagagt
     3481 aaagtattgc tggacataca tatagttttt taccagccat tattttgtaa cctttggcct
     3541 taacagcttc ttttagataa ggttcatgtt gaaatagatt tgcatcaatt tcaccattat
     3601 ttaaagcttc atttggaagt atgtaatcat caaagttttt aacttctaaa gtatatcctt
     3661 tttctttaat aagtggtttt aattcttcta ataactctcc tcctggaact aaagtagcac
     3721 caacaacaat ttttttatca tctttagctt tagaacatcc aaccacagct aaagttaata
     3781 ctagacataa taacaaacat aataattttt tgaatttcat ataaattccc tcctgaatat
     3841 aattgattag ttaaaaataa aataccattc tttatcacac tgcaaaataa aaataagcct
     3901 gagtttaaac tcaggcttta aaagctaatt tagactcatc tttcagtata atactgcagg
     3961 atttagcacc aatgtatata gaaaatatac tggttgctgg gtttcatagg gccagtccct
     4021 tcaccactct ggataagaag tatcaatttt taattatgtt ataaatatta tcatgatttt
     4081 ttacgtctgt aaacataatt ttataaatat tttaaaatct ttaatgtatt ttatttaaca
     4141 cctaaaattc cagaaactag aatatcagta tcagcaccta agaaatagtc atttatttca
     4201 atagaatcca gagtatttct caaagcattt tcttcatgcc ttataccaat aagtttattt
     4261 tctacaaatg caacatcaca ttttccaaaa aaatctccaa aaaattttat actagttatt
     4321 atgcctttat caacatttaa attaaactca acatttccac cagaatattt taattcattt
     4381 gaaagagtat attttggtga attaccaaaa ttccaatccc aagtttcgta ttttgattta
     4441 gtaagctttt ctatttgttt tatatcatgc tcactcaaac aataattagt attatcagta
     4501 tttgttttag aaagataatc cattatagca tctttaaatt ctaatatatc catttttgaa
     4561 tgtaaatgtt cacttatatt ggttacacga gattttacag attttattcc ttttccttca
     4621 aattttatag gtttaacctt taatgctttt gagaggtcat ttatttcaga tgaaaataaa
     4681 agagtcccat gatgcattac tttgtttttg tagttgtatt gagcatttcc agaaaatttc
     4741 ttgccatcta taagaaggtc atttcttcca gaaaattcgg cattgacatc tagtgtttta
     4801 agtaaatcta ttatgggctg agtgaatctt ctgaaatcac taaaattatt attgttacaa
     4861 gctataaatg taaaatttat atttcccaaa tcatgaaata cagctccacc accagactgt
     4921 ctcctaacga caggtataga atattctttt atatattcta aatttatttc agaaagtgtg
     4981 ttttggtttt ttccaacaat tatagaaggt tcattcctcc ataaaataaa taagtcttca
     5041 tcaaaatttt ttagaagata ttcttccatt gctaaattaa aataagggtt tgttttttca
     5101 ttataaatta ataacattaa agtagttcct ccatagaatt gataaaattt ttattatgaa
     5161 tacaattaat tttataattc gacaataata taaaaactcc tttaaattag aaattttaaa
     5221 aactaccttg caaagtttaa ataaataata tatactcaaa atatgtttaa taaaagtgaa
     5281 tagaagggta gaggcgcaat aatctatcag tactaataag gagttaagca cagagattta
     5341 ttaggaaagg agatattgcc gaagttttat aatcgatgct ttaagattat attgctgggg
     5401 gtacatagaa aatatgtaca actgtcacag gtttatttgt ggtgagctat catttaagga
     5461 attatattat atttattttt actattgttg atatattgta atgtttaagc cttgagtgtt
     5521 taccactcaa ggctttttta gttttattgt aacataatac cctgtacagt tcacaaaatt
     5581 aaaaggagag ggagatttat atgaggaaca aaaaaattaa tattattttt ctgacgacaa
     5641 tcatgttcat aatgtcaaca gtaatggttt ttgcagaaga agatatagac actattgcac
     5701 tagccaatgc agaaaaattt gggattttaa ctttaatacc accattagtt gctataatac
     5761 ttgcatttat aactaaaaac gtaataattt ctttacttat aggtattctt tctggtagtt
     5821 ttataattaa agctagtggt attaatgttt ttgcgacatt tatacaggca tttttagatt
     5881 tagtagacag agctttagta tctttagcag acccttggaa tgcagggata atactacagg
     5941 ttttggcaat tggaggagta ataaatcttg ttgctaaaat gggaggagct aaagctatag
     6001 ctgaagcact tgctaaaaga gcaaagtcag caaaagggac acagcttata acatggtttt
     6061 tggggctttt agtattcttt gatgattatg ccaattcact aatagtaggt cctatgatga
     6121 gacctgttgc agataaaatg aaaatatcga gagaaaagct ggcatttata atagatgcca
     6181 cagcagcacc agttgctggt ttagctataa tatctacatg gataggtctt gaggttggtt
     6241 taatacatga tgcttttgaa agtataagta tagatgtaga tgcatttggt atatttttaa
     6301 atacaatacc atttagattt tacaatatat taatattagc tttcattgta atatcagcat
     6361 tattattaaa agaatttggt ccaatgagaa aagctgagat aaaatctaga agtagaaaaa
     6421 ttagtataga ccttgatgaa ggcgtagaag agttggatga tttagctcca aaaaatggag
     6481 tgaaattgag tgtatggaat gctataatcc caataggaac attgataata gttgcattag
     6541 catcatttta ttatagtgga tatacatcta taatgggagg agacgataag gctctgatac
     6601 aactatttac aaattctcca tattcttttg aagcaataaa agaagcattt agtgcatctg
     6661 atgcatctag agcattattc cagtctgcac ttgttgcaag tttagttgct attataatgg
     6721 ctgtagtaaa aaagattttt acaatatcag aagcaattga tgtttggata gatggaatga
     6781 aaagtttagt aatcactggt gtaatattaa tacttgcatg gtcattaagt tcagtaataa
     6841 aagagttagg tacagctaaa tttttaatac acctattatc aggttcacta ccaccattct
     6901 tattaccaag tttaatattt ggtttaggag caataatatc ttttgctact ggaacagctt
     6961 atggaacaat gggtatactt atgccacttg caattccatt agcatactca ttaaatcctg
     7021 atatgtctta tgtaatagta agtactagtg cagttttaac aggtgcaata tttggagacc
     7081 attgttctcc aatttcagat acaacaatac tttcttcaat gggagctggc tgtaatcata
     7141 tagaccatgt taacactcaa atgccatatg ctatatttac agcagtaatc actattgtat
     7201 ttgggtatat accagctgga cttggattgc caatatatat agtattacca gtggcaatag
     7261 ctgctatatt tgtaggtatt caaataattg gtaagaaagt tgatgaagcg gaaatagaac
     7321 ttgtagaata aagatataaa taagtttcac cttttattat cactattttg ttagttttta
     7381 gataatttta aaaagttatt gaaaataatg gcgaaatata gtaaaataaa agagtgataa
     7441 gcggatgtgg cggaattggc agacgcacta gacttaggat ctagcgccat tggcgtgggg
     7501 gttcgactcc cttcatccgc actttacagt acttaattgt actgaaaaaa actggggttg
     7561 ctggctttcg gagtgggcta tcccgttttt atttttttgt atatataata gattggcact
     7621 ttagtataag gtgctttttt tataggcaaa aacagtacat ttatttctgt tttattatca
     7681 ttcatctatt agaatatact ttagttaaga atgtgttaat aagcagtgtt cacattcttg
     7741 ataaaatgtg gaataatatg tatttttact aagacggaaa tgaaataatt aaaccattaa
     7801 ataatattat aagatgatga ataagtagat aaatcaaatt ttgtaggagg atattatgga
     7861 aaaatatata tggttgtttc cattactttt tatttttcat gatatggaag agataatagg
     7921 ttttggaata tggcttaaaa aaaataaatc aatgcttgat aagaagtatc catttatcag
     7981 taaagtttat gaaaattata gtactgaagg catggcattt gctgtgtttg aagaatttat
     8041 tttatgcatt attttctgta tacttacagt tataacagag aatcagtatg tatatctact
     8101 atggttaggt agttttatag catatacctt acatttggta attcatatag ggcagtcaat
     8161 cataataaga aaatatatac cttcacttat taccagtatc atatgcttac caataagcat
     8221 ttggtgtata agtaagagta tttatatagt tgattgtgaa atgagtacaa caattctgta
     8281 cagtataatt ggcattataa ttgtagcatt gaatttaaag tttgcacagt cgctgattgg
     8341 aaaatttaca aagtggatgt caaacatata aattttagtt tattggacag ttcaaggaat
     8401 cagaaattgg aattttatag tattaatatt ttatagtatt aatataatgt ataaaatttt
     8461 atagcaatgt atttcataag tataaagtga ctagaatttt aagaaatata caaattctat
     8521 aaaaactaaa taatttcaag tatattttaa aaatcttatt tttcacaagt ttaaaattgt
     8581 aaacgatttc atcaagtcta tgaatatact tttaacatgt tatagtaaat ctcaatataa
     8641 atttacattt ggttctttgt gtgttatttt aataataaat taagtgaaaa tgttatttta
     8701 cattaatata taatatcttt gcataagagt gaataatata aaagagaaat aattgataat
     8761 aaaaacttaa caaaaaaatt aatacataaa aaaaaataaa tataatgtgt tgacatttaa
     8821 ttgaaatatt catacaataa aattgaaaat aaatatttcc aaatgagatt agcgagagag
     8881 tcctttatac gaaaaggcgc cgaagaagaa atttaagaaa tgccaatttt tagagaagct
     8941 ttcaggcaaa aatatcgcta attgatggga ctctggagag acttaagtta agatactata
     9001 agtcaccgaa gaagcaaaat aatattaaat tattaaatct ttcaggtata caaacaggga
     9061 tatataggct aggattattt tccatgctga tatatctttt ttttatgaaa aagtacagga
     9121 aataatatca aagttactta aatacagtag gtctaatttt ctagggaggg ttatatatga
     9181 atgaattgaa aagagtatct ttgtacaata tacacaaaga gcttggagca aaacttgttg
     9241 aatttgctgg ttgggaaatg cctttagaat atgagggtat aaataaagag catgagaagg
     9301 tcagaaaaag tgcaggtata tttgatgtat ctcatatggg agaggtacag ataaagggag
     9361 cagagtcaga aaaatttata caaaacctag ttacaaatga tataagcaca ttaaagataa
     9421 atgacattat atatacacct atgtgttatg aaaatggtgg agtagttgat gatttattaa
     9481 tatataaatt tggtgaagaa gattatttat tagtaataaa tgcaggtaat atagataaag
     9541 atgtagcatg gataataaaa caaagtgaag gatacaatgt agatataaaa aatatatcta
     9601 gtgaagtgag tcaattagca attcaaggac ctaaagcaga agaaattctt caaaaaatca
     9661 cagatataga cttaaactca ataaaatttt ataagtcaat tccatcaaca aaagtatgtg
     9721 gttgtccttg tttagtttca agaacaggat atactgggga agatgggttt gagatatact
     9781 gtaaaaataa atatgtagaa ataatttgga atgaagttct aaaggttgga ggagaagata
     9841 tatgtccagc tggtctaggt tgtagggata ctttgagatt tgaagcagct ctacctctat
     9901 atggacatga aataaatgaa cacatatctc caattgaagg tggtttatct atctttgtga
     9961 aaacaaataa agaatcattt attggcaaat caattttatc aaaagaaaaa gaaagtggag
    10021 ctaaaagaaa gttagtagga tttgaaatgc aaggtaaagg aatgcctaga aatggatatg
    10081 atataaggat tggtgataaa acagttggat ttgtaacaac aggatgtgca tctccaacga
    10141 caggaaaaat tttaggtatg ggaattatag attctgaata tgcaaaagta ggaaatgaaa
    10201 taggtatagc aatcagaaaa aaagttgttc ctgctgtgat agttaagaaa cctttttata
    10261 aaaaacaata taaaaaagat aatattatat taaacaaaga aaataaattt tcatatatac
    10321 ctgctacaag tgaagataaa tcaaaaatgt taaaagtagt tggattaaat tcagttgatg
    10381 aattattttc agatatacca gaagaagtaa aattaaaaag agatttaaat ttggaaattg
    10441 gaaaatctga attagaggta agcaaaatag taaaaagatt gtcagaagaa aatttaagtt
    10501 tagaagactt gacttgtttt cttggtgctg gtgcatatga ccattatata ccatcaatta
    10561 taaaacatat aacttcaaga tctgaatttt atacagcata tactccatat caagctgaaa
    10621 taagtcaggg aactttacaa gtagtttttg aatttcaatc tatgattgca gaaattacag
    10681 gtatggaaat tgcaaatgca tcaatgtatg atggagcaac tgctgcaata gaagcatgta
    10741 taatggcaat gaatcagact agaaaaagta aaatagtagt gtcaaaaact attcatcctg
    10801 aaactctgtc agtattaaga acttacttac aatataaaga ttgtgagata gtagaaattg
    10861 acttttgtaa tgaatatggg actacagata tagaaaaatt aaaagcttct gtagacaaag
    10921 atacagcatg tgttcttata caaactccta atttctttgg aattattgaa gaaatggaag
    10981 aaatagaaaa gataactcat gaaaataagg ctatgttaat tatgagtgta gacccaatat
    11041 cattaggagt tttaaaaaca ccaggtgaga taggtgcaga tattgttgtt ggagaagctc
    11101 aatcacttgg aaaccctctt aattttggag gtccttatgt aggattttta gctagcaaat
    11161 ctaaatatac tagaaaaatg ccaggaagaa tagttgggca aagtttagat gtagaaggta
    11221 aaattgcata tgtattaact ttacaaacta gagaacagca tgtaagaaga gaaaaagcaa
    11281 cttctaatat atgttcaaat caagctttaa atgctcttgt agcttcaata tatatggcta
    11341 ctatgggtaa agaaggattt aaagaggttg gtatgcagtc tatgaaaaaa gcacattata
    11401 cctacaataa acttgtacaa actggaaaat ataagccaat atttaaaggt aagtttttca
    11461 aagaatttgc tgtacaagga aatcttaata tagaaactat aaatgataaa ctcttagaag
    11521 aaaatatatt aggtggttat aatttagaat acaattatcc agaattaaaa aattcaactt
    11581 tgctttgtgt gactgagaaa agaagcaaag aggaaataga taagttagtt ggaataatgg
    11641 agggattata atgaaagaat acaatagttt gttgatagat atatctaaaa aaggtaggaa
    11701 agcatactca cttccaaagt tagatataga tgatataaaa atagaagata tgattgaccc
    11761 agatatggca agacaaagtg agttgaattt gccagaagtt ggtgaattag aattagttag
    11821 acattataca ttattatcaa ataaaaactt tggagttgat acaggttttt atcctttggg
    11881 ttcttgtact atgaaatata atcctaaaat aaatgaagat atggcagcac ttccaaactt
    11941 tactggaatg catccatacc aatcttcgga tacagctcaa ggttctcttt ctttgatgta
    12001 tgatttatca agaagacttg cagaaattac aggtatggat gaagttacac tacaaccttc
    12061 agcaggttct catggtgagt ttacagggct tatgattata aaagcatatc atgaaaatag
    12121 aggtgaccat aagagaacca aagtgataat tccagattct gcacatggaa caaatccagc
    12181 aagtgcagct atggcaaact ttgatgtgat tcaaatagca tctgataaaa atggagctgt
    12241 agacataaat gtattaaaag aggttttgaa tgatgaagta gcagctctta tgcttactaa
    12301 tccaagtact cttggtttat ttgaaaaaaa tataaaagaa atagctactc ttgtacatga
    12361 agcaggagga cttttgtact atgatggtgc aaacatgaac gctattatgg ggataacaag
    12421 acctggagat atggggtttg atgtggttca tcttaatctt cataagactt tttcaactcc
    12481 tcatggaggt ggaggtccag gagctggtcc tgttggagtt aaaaaagaat tagtaccttt
    12541 tttaccaata ccagtaattg aaagaaaaga agataagtat gtactaaatt atgatagaga
    12601 aaaatctatt gggaaaatta aaaatttcta tggtaatttt ggagttcttg taagagctta
    12661 cacatatata ctaactatgg gaagggatgg acttaaagag gctagtgaaa tggcagtttt
    12721 aaatgctaat tatataaagg aaagtataaa agatgattat attttgccaa tagatacctt
    12781 gtgtaagcat gagtttgtat taggtggatt gccaagagga gaggccaata taaaaactat
    12841 cgatattgca aaaagactac tagattatgg ataccatcct ccaacaatgt actttcctct
    12901 tattataaat gaggcactta tgatagaacc tacagaaagt gagagtatag agacattaga
    12961 tagttttata gaagctatga aaagtgttgc taaagaggca aaggaagaac cagaactatt
    13021 gaaaactgct ccacataata ctttggtcaa aagagtagat gatgcaaggg cagtaaagaa
    13081 acctatacta acatggtcac aaagataaat agttaaaaag tagagattta aagtataaag
    13141 agaattaaat ttataagaaa aagctatcta acttaatcta gtttagatag cttttttgta
    13201 tattagtata tatggtattt cctatataaa gttttaaatt atattagtgc ttatatagaa
    13261 tattgatatg atgattatgt atagatatta ataagaattg ttgaatttat cttgccttaa
    13321 ctttatttac tcttttatat taagaaaaac ttaactaaaa tatagcgaaa ttcataaaaa
    13381 tttaggaaat cttaagaatt a
//
LOCUS       DAMKNB010000090        13230 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.096, whole genome shotgun sequence.
ACCESSION   DAMKNB010000090 DAMKNB010000000
VERSION     DAMKNB010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 13230)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13230)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13230
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.096"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            complement(<1..591)
                     /locus_tag="PC494_003021"
     CDS             complement(<1..591)
                     /locus_tag="PC494_003021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HDF3913503.1"
                     /translation="MLNETRKKQLTEVCQDLIRNASYSGQEENVVKAIEENFALLGFD
                     SWSRDRYGNIVGCIKGNKPGKKILFDGHIDTVPVPDASKWSVPPFEARIVDGKIYGRG
                     TSDMKGQVSAMMAAVSYFAEDTNKDFEGELYVAGVVHEEIFEGVSAREISKAVQPDYV
                     VIGESSELNLKIGQRGRGEIVVETFGKPAHSANPEKG"
     gene            complement(856..2070)
                     /gene="dpaL"
                     /locus_tag="PC494_003022"
     CDS             complement(856..2070)
                     /gene="dpaL"
                     /locus_tag="PC494_003022"
                     /EC_number="4.3.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopropionate ammonia-lyase"
                     /protein_id="HDF3913504.1"
                     /translation="MREIKWKLNNLPKSEEKEKGIEFLKDEEIAKAKAFHESFPQYEK
                     TPLVKLDNLAKSLGVSGIYVKDESYRFGLNAFKVLGGSYSMGRYLAQRLNTDISELGY
                     DKLTSKEIKEKLGEITFFTATDGNHGRGVAWTANKLGQKSVVLMPKGSSEFRLNKIKG
                     EGADASITDLNYDDAVRLANDYAEADDHGVMVQDTAWDGYEEIPAWIMQGYGTMAKEA
                     IEQLKEYGVDRPTHVFVQAGVGSLAGAVQGYVASIYDECPITVVVEADEADCYYKSAK
                     AGDGKPRFVGGDMPTIMAGLACGEPNIIGFEVLKNYSSAFVSAPDWVSAKGMRILGNP
                     LRGDEKVISGESGAVTTGALVSILESEDLKDLREALKLDENSKVLLISTEGDTDPDKY
                     RDIVWNGECQSK"
     gene            complement(2684..3222)
                     /locus_tag="PC494_003023"
                     /pseudo
     CDS             complement(2684..3222)
                     /locus_tag="PC494_003023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427977.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="2'-5' RNA ligase family protein"
     gene            complement(3299..5104)
                     /locus_tag="PC494_003024"
     CDS             complement(3299..5104)
                     /locus_tag="PC494_003024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDF3913505.1"
                     /translation="MLSKLKEFQQEMIKYTETVASVLDVDIEIVDDRLIRISGTGLYK
                     SKINESVVTEGFIYDNVIQTGQELVVLDICDNQLCIECSHYMKCLNKVIIAVPIKYNN
                     RTIGVIGAISTDKTKKVEISAKIDNYLKFVNHICDLISMKIEEHEASKNSSRKMDMMI
                     EIIENVEKGVIILDINSKISYINNIALKKLDIDKNIIENIVNIVSVESSSNGHELLEI
                     DIDNKIYNINAKIIPVYPYINQYDKIIIFDKTYINHKGHGKVNSGWGNSDIESIIGNS
                     EAMLKVKERTKKLAKSNSTVLITGESGTGKELIARAIHAEGSRWNKPFIAINCAAIPE
                     NLLESELFGYIKGAFSGASSGGKVGKFELANEGVIFLDEIGDLSMPLQAKLLRVLQER
                     KFARIGSNKLIDLDIRVIAATNKNLLKLVNEGKFRDDLYYRLNVIPINLPPLRERKDD
                     IEAIMMKFASKYSLELGIQLNKIEENVMNMLINYNWPGNIRELENAVEYMMNLVGDDG
                     IIYKDMLPLDILNYYNINGNIYKNKDVNIIFEDDIVGGIVENQERILSIKELELTYIN
                     KLLNKYGRDTKTKKKIAKDLGIGLATLYRKLEEEQ"
     gene            complement(5500..5877)
                     /locus_tag="PC494_003025"
     CDS             complement(5500..5877)
                     /locus_tag="PC494_003025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003483933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HDF3913506.1"
                     /translation="MSKVVIATEKAPGAIGPYSQAIQVGNIVSTSGQLPIDMKTGELV
                     SDPKEATKASLDNVKAILEQAGTSMDKIFKTTVFVKDLKDFNDINEVYATYFKENPPA
                     RSCVQVAQLPKDAVLEIEAMAVL"
     gene            6782..7267
                     /locus_tag="PC494_003026"
     CDS             6782..7267
                     /locus_tag="PC494_003026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3913507.1"
                     /translation="MSKSELTAETTEEMLEVLSGKDYDIACHLHELGKSLDCKIEPKT
                     GARSYKIVYSTKKPKRSLFTIECNEKKWRVKANLFHLNTYKDAVEECSKTIKDSITKT
                     RTCKKCNSKCIGGSSFELDGKSYLTCIGSGHYFANMEEMDWKNLEKLITKENNIMQES
                     V"
     gene            complement(7467..8006)
                     /locus_tag="PC494_003027"
     CDS             complement(7467..8006)
                     /locus_tag="PC494_003027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HDF3913508.1"
                     /translation="MSKNVLIVSASPRKGGNSDLLCDQFIQGVLESKNQVEKIFLKDK
                     DINYCTGCGACYEKEANCSQTDDMGEILEKMIGADVIVLATPVYFYTMNAQMKTMIDR
                     TCSRYTEICDKDFYFIVTAADENVADMERTIEGFRGFTSCLNGSKEKGIVYGVGAWNV
                     GDIKGSKAMKQAYEMGKLA"
     gene            complement(7999..8412)
                     /locus_tag="PC494_003028"
     CDS             complement(7999..8412)
                     /locus_tag="PC494_003028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HDF3913509.1"
                     /translation="MTISEVSKKYELSADTLRYYERIGLIPPVNRNKSGIRSFTEEDC
                     EWVNFIKCMRGAGLSIETLIEYVAMFQQGSSTIKARKELLIEQRNQLAKRIEEMQKTL
                     ERLNFKIDRYEEGIIEKEKVLKSSRNKKMEAVSYE"
     gene            complement(8448..9569)
                     /locus_tag="PC494_003029"
     CDS             complement(8448..9569)
                     /locus_tag="PC494_003029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HDF3913510.1"
                     /translation="MEAKKLGFGLMRLPIKDENDVTTIDMEHLNKMVDTFLERGFTYF
                     DTAYVYHMGKSEIALRESLVKRHKRESFTIATKLPLMALKKKEEQETIFNEQLEKCGV
                     DYFDYYLLHNIGVSHYEVAKKFDSFKFIEEKKKEGKIKNIGFSFHDSAELLDKVLSEH
                     PEVDFVQLQINYLDWDNESIQSRKCYEVAEKHNKPVIVMEPVKGGTLAKIPEKAEKLL
                     NDYNPDMSISSWAIRFAASKDNVMMVLSGMSNMEQLLDNTGYMQNFKPFVQEEYNIID
                     EAVEIINESILIPCTACQYCVEGCPKNIAIPNYFALYNAEKQALNTGFSTQMVYYNNY
                     TKTYGKASDCIECKQCEESCPQHIKIIDALKNVAETFEK"
     gene            10168..11820
                     /locus_tag="PC494_003030"
     CDS             10168..11820
                     /locus_tag="PC494_003030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp21"
                     /protein_id="HDF3913511.1"
                     /translation="MNKKNLAILISGMMFFSSSSAIFADNTTKQERLIGKTRYETAVE
                     VSKLGWVQSKTAIIVNGNSIQSALCANPFAKLKNAPILLVNNNSIENSTKAELKRLGV
                     DNVYIVDSGNSISSKVENEIKSLNIKINKIVGNNIYEMSTNVLKEIDKIKKVENVAVV
                     NGLKGLSDAVSIASPAAIHNMPIILVSDENSNDSSINFLNNRSIKKSYIVGGNKILSD
                     NTVKKYPNRERISGSDRNNTNAKIIDKFYKDKKINNVFVAKDGINQENALVDSLSIGV
                     LAAKENSPIMISNGSLVNSQKEFIKNKDIDEITQVGGGYNQKAFEDILKLKNVNIRNK
                     TKKISLIQAKEILKQALPGSNILVCYYDEDDNEYDCKVIKDNILYEIEIDAYSGKIIE
                     IEKDDDLNDNNLGTQNISLDKAKSIALDAIPNGNLIYCKYDAEDNEYEAKVIKNKKTY
                     ELEISAFDGRIVDIDMDNDSDDDFDDNDKNNSNTNDNSSIISAEKAKSIMLDKVPGGK
                     IVKFKYDEDDKEYEGEIIKGKTEYEITINAITGKILEFEIDD"
     gene            complement(12179..13105)
                     /locus_tag="PC494_003031"
     CDS             complement(12179..13105)
                     /locus_tag="PC494_003031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conserved phage C-terminal domain-containing
                     protein"
                     /protein_id="HDF3913512.1"
                     /translation="MSNSFYQLNSAVLYFNEKRDVNRIRFNHYVMRKENIQRLKGTLP
                     RGQFMMTVRKAASDLDVSISTISRLVNEFIDLGILRLISRGVKGNCCSVYSYVCSESS
                     NAEIVTKNGDIFKNIEKYIDATINNNQKTMKYKHRNELFKNSNTNIYSRINQESIDKD
                     YDLIIHTGYETENETKKKELLKNNLNKKNLNKNTFENSDEDLTEDSTYKNPESIHEII
                     IRKLNSESGKNFKADLSITKALIDKRLKEGYSLEDFYKVIEAKVRRWRYTDMEIYIEP
                     TILFGYEFESYLNEESSLSACNYGDMCYEDMY"
BASE COUNT         4404 a         2218 c         1476 g         5132 t
ORIGIN      
        1 acctttttct ggattagcag agtgagctgg tttaccaaaa gtttctacta ctatttctcc
       61 tctacctctt tgacctatct ttaggtttaa ttctgaagat tcacctatta caacataatc
      121 aggttgaaca gccttactta tctctctagc tgaaacacct tcaaatattt cttcatgaac
      181 aacacctgct acatacaatt caccttcaaa gtctttgtta gtatcttctg caaagtatga
      241 aacagcagcc atcatagcac ttacttgccc cttcatatca gaagttcctc taccatatat
      301 tttcccatct actattctcg cttcaaaagg aggaacactc catttacttg catctggaac
      361 tggaactgta tctatatgtc cgtcaaataa tattttttta cctggtttat ttccttttat
      421 acatcctact atatttccat atctatctct tgaccaacta tcaaaaccta gtaaagcaaa
      481 attttcttct atagctttta ctacgttttc ttcttgacct gaataactag catttcttat
      541 taagtcttgg catacttcag ttaattgttt ttttcttgtt tcatttaaca ttttgatatt
      601 cccccatata atttttaatt tgttgacgtt ttattttgat atttcacttt tttaatttat
      661 tagcatttca cttaatctat tgatttttta tttctttata ttttatttat taaattttta
      721 tttagacttt attttaattt tatttggttt tatttaattt tatttagttt ttattttgaa
      781 tttttcattt gctttacttt tttatttgct ttactttttc atttatttat taagtttttc
      841 ttttccttaa gtcttttatt tactttggca ttcaccattc caaactatat ctctatattt
      901 atcagggtca gtatctcctt ctgtacttat taataatact ttagagttct catctagttt
      961 caaagcttct cttaagtctt ttaaatcttc actttcaagg attgaaacta atgctccagt
     1021 tgtaactgct ccagattctc cagagattac tttctcatct cctcttagag ggtttcctaa
     1081 tattctcata cctttagcag atacccagtc tggtgctgaa acgaatgctg atgaataatt
     1141 ttttaacact tcaaaaccta taatgtttgg ttctccacaa gcaagccctg ccattatagt
     1201 tggcatatct cctccaacaa atcttggttt tccatctcca gcttttgctg atttatagta
     1261 acaatcagcc tcatcagcct ctactactac tgttattggg cattcatcat atattgaagc
     1321 aacataccct tgaactgcac cagcaagtga accaactcct gcttgaacaa atacgtgtgt
     1381 tggtctatct actccatatt cttttaattg ttctatagct tctttagcca tagttccata
     1441 tccttgcatt atccatgctg gtatttcttc atatccgtcc catgctgtat cttgaaccat
     1501 tactccatgg tcatcagctt ctgcataatc attagctaat cttactgcat catcatagtt
     1561 taagtctgtt atactagcat ctgcaccttc tcctttgatt ttatttaatc taaattcaga
     1621 agaacctttt ggcattaata caacagattt ttgacctaat ttattagctg tccaagcaac
     1681 tcctctacca tgatttccat ctgtggctgt aaagaaagtt atttctccta atttttcttt
     1741 tatttctttt gaagttaatt tatcataccc taactcagat atatctgtat ttaatctttg
     1801 agctaagtat ctacccatag agtaagaacc acctaaaact ttaaatgcat ttaaaccaaa
     1861 tctataagat tcgtctttaa catatattcc gcttacgcct agtgattttg ctaagttatc
     1921 taatttaact aaaggagtct tttcatattg tggaaagctt tcatgaaaag ctttagcctt
     1981 tgcaatctct tcatctttta aaaattcaat tcctttttct ttttcctctg atttaggtaa
     2041 gttatttaat ttccatttta tttctctcat ttattttata ttcccctttc aaatttttcg
     2101 gtgtcatttt aattttttat ctttgtgcct tatagcaaag caattaccgt gccaatatta
     2161 tttattctaa aaacaatttt tttatgttgg aattacatac ttttataaaa tttctttaaa
     2221 gtttataaat tttgagtgtg aaaaataaga tttataaaag aaaaaattct catattggga
     2281 aatttttatc aatacgagaa ttatcaattc gagaaatcgt ttatttgtct taattcttcc
     2341 tttattatgc tcttattttt tatatgtcta ttgttttgtc agatatatta ctacttttat
     2401 tttctataaa tatatggcta taaccttctt acgcataaac tctataaatt tatatacttt
     2461 atatacttta tattctttat tacccaaagc ctccaaaatg gcttaaatct tttcatagct
     2521 tcttacagaa gtttacatgg tcatcccccc aataagcaaa agtgcaatat gtgtaccatt
     2581 gtgccctact tgcgactatt gagctgtcga aattcgcaac ttcgcattta tctgatgaaa
     2641 tgcactatac aaaatattca taacatccac aacagagtta aagttaccta ttcatattca
     2701 ctgtaaaaat ttcttccaca ggaaatgtaa ttttaaccaa tcctattgag acaaactcac
     2761 cacttatttt tttgaactca cgcagtaata catcacttgc ccgaaaaaaa gcctcacttt
     2821 catcatctcc agtaagtgct attgtgcaat ggggtaccca acgattgggg tgtaccattc
     2881 ccaaccattt gaatcaaaat cttgtagtac ctcatataat tctctctgaa actgatacat
     2941 actgctattc attataggtg atacaaacac cgttttagta tcattaaaca tgcctactga
     3001 accaatgtaa gcaggtatta ccttatggtt ttgtgcaaac ccctttagct tgtctatgca
     3061 acaagcctca tccacatcat tgaaacaagc caaagtaaga tgaggtcttg ttttccattc
     3121 taagtacttc gtactaattt tttcatcagc gattttttta gataaatcaa aaagttgctt
     3181 ttccgttttt ttatcataat atagctctat cgcatattgc ataataacac ctccaccata
     3241 aagtaaaaat acctatctat aaaaacacac aaatacctat cattttaata ttatattact
     3301 actgttcctc ttccaatttt ctatatagtg tagccaaacc tatgcctaag tcttttgcta
     3361 tcttcttctt cgtctttgta tctcttccat acttattcaa caacttgttt atgtaagtca
     3421 actctaattc tttaattgaa agtatccttt cttgattctc tactatccct ccaactatat
     3481 catcttcaaa tattatattt acatccttat ttttataaat atttccatta atattataat
     3541 agtttaaaat atctaatgga agcatatctt tatatattat tccatcatct ccaaccaaat
     3601 tcatcatata ttcaactgca ttttccagtt cccttatatt tcccggccaa ttatagttaa
     3661 tcaacatatt cattacattt tcttctattt tatttaactg aatacctaat tctaaagaat
     3721 atttagaagc aaacttcatc attattgcct caatatcatc ctttctttcc ctaagaggtg
     3781 gcaaatttat aggaattaca ttcaatctat agtataaatc atccctaaac ttaccttcat
     3841 ttactaattt caataagttt ttatttgtag cagcaatcac tcttatatct aaatctataa
     3901 gtttatttga cccaattctc gcaaattttc tctcttgtaa aactctaagt aactttgctt
     3961 gtaaaggcat tgacaaatct cctatttcat caagaaatat aacaccttca tttgcaagtt
     4021 caaatttacc tactttacct ccactactag ctccactaaa tgcacctttt atatagccaa
     4081 atagctcact ttcaaggaga ttttctggaa tagcagcaca gtttatcgca ataaatggct
     4141 tgttccatct gctaccttca gcatgtatag ccctagcaat tagctcttta cccgtaccac
     4201 tttctccagt tataagtaca gttgaatttg attttgctaa tttcttagtt ctctctttta
     4261 cttttaacat tgcttctgaa tttccaatta tagactctat atcactattt ccccagccac
     4321 tattcacttt tccatgtcct ttatgattga tatatgtctt gtcaaatatt attattttgt
     4381 cgtattgatt tatatatgga tataccggaa ttattttggc atttatatta taaattttgt
     4441 tatcaatatc aatttctagt aattcatgtc catttgagga agattcaaca gatactatat
     4501 ttactatatt ttctattata tttttatcta tatctaattt ttttagagct atattgttta
     4561 tataagatat tttgctattt atgtctagta ttataacgcc tttttcaaca ttttcaatga
     4621 tttctatcat catatccatt tttctactgc tattttttga cgcttcatgt tcttctattt
     4681 tcatagaaat taaatcgcat atatgattga caaattttaa ataattatct atttttgcac
     4741 ttatttctac ttttttagtt ttatctgtac taatagcacc aattactcct atagttcgat
     4801 tattatattt tattggaact gctattatta ctttatttag gcatttcatg taatgggaac
     4861 attctataca aagctgatta tcacatatat ccaatacgac taattcctga cctgtctgta
     4921 taacattgtc ataaataaat ccttctgtaa caacgctttc atttatcttt gatttataca
     4981 gacctgtacc actaattctt attaatctat cgtcaactat ttcaatatct acatctaaca
     5041 cactagctac tgtttcagtg tattttatca tttcttgttg aaattctttt aatttactta
     5101 acatagtttc ccccattaga atttaattta ccaaattatc agtttagcta tattttaaca
     5161 tatagtcact ctttaaaata tatataaaac attacttatt tatatatttg cgttaaaaca
     5221 gacaatatta atttataaaa agtttgtttt atatagtaac cttaattata atatgcagac
     5281 aataaaataa atcacaatac aataataaaa aaaagctttc ctcatataac aaatatattt
     5341 ttgacataaa aatatacatt atatgagaaa agctcaatag ttaaatattt agatagattt
     5401 ttatatagac ttttttaata taaacttttt taattgtaga ctttttttat tagtttttaa
     5461 tttttattag ttttgttatt ggttttattg ttataatact tataatactg ccattgcttc
     5521 aatttctaaa actgcatctt ttggtaattg agcaacttgt acgcatgacc ttgctggtgg
     5581 attttcttta aaatatgtag catatacttc attaatatca ttaaaatcct ttaaatcttt
     5641 tacgaatact gtagtcttaa atattttatc catacttgta ccagcttgtt ctaatattgc
     5701 ttttacatta tctaaagaag cttttgttgc ttcttttggg tcagatacta actcgccagt
     5761 cttcatatct attggaagtt gacctgatgt agaaactatg tttccaactt gaattgcttg
     5821 agaatatggt ccaattgctc ctggagcttt ctctgtagct attactactt ttgacatgac
     5881 ttcacctcct attattaagt tatatttaca ggaaaataaa atttcctaaa caccaatatt
     5941 aatacgaacc tttagattaa atttcaaatc taaaacttca aataatcaat acttagatga
     6001 ttatgtttat ttgtgtcttg ttaactttta ttaaagcaat taacgtgcca aactttattt
     6061 atatataaaa ttttgtgaag tcattcaaaa tagttacttc tgaatttttt cgtaaaaaaa
     6121 cgctctaaaa ttactttttt atgatgtcaa tttttttctc atatctagaa atttaccaac
     6181 atgagaattc ttgttttgag aatttacaga ttaaagttat tttttaacct taaattctga
     6241 acctcccatg actaaagtca cagggttcct gcttcataga attttgcata atcaagttat
     6301 tacatatgaa agaactatag ttgacaatcc cactattata aataataaaa cctttaccca
     6361 taccttattt accctagtta tcatagagcc tattgaaaat ataacagcta aatataataa
     6421 taaccaaaaa attatcaata tctaccactg ttgctgaaaa tccaaaaaac taccttttga
     6481 tagtcttact taacaatcta attaatctca taataaattt acaacttata aataaattgt
     6541 tatattggcc gtatctcaac aactttctcc tttcctagtt ttaaatcttt tatagaattg
     6601 taccacgtct aagtaaattt tcatactatt aagtcttatt tctaataaat cattagctct
     6661 cattctatgc ccaataatgt aagattgcag taattttatt gattttcata gttttattta
     6721 atatacttac attaattatt ttcatatgaa attattattt atataggggg atttttttaa
     6781 tatgagcaaa agtgaattaa cagcagaaac aacagaagaa atgttagaag tactaagtgg
     6841 taaagattat gatattgcat gtcatttaca tgaacttggt aaatcattag attgtaaaat
     6901 tgaaccaaaa acaggtgctc gttcttacaa aatagtatat tcaactaaga aaccaaaacg
     6961 tagcttattt actattgaat gtaatgaaaa aaaatggaga gttaaagcaa atctttttca
     7021 tctaaataca tataaagatg ctgtggagga atgctctaaa actattaaag atagtataac
     7081 taaaactcgt acttgtaaga aatgtaattc aaagtgtatt ggaggttctt cgtttgaatt
     7141 agatggaaag tcttacctga cttgcatagg aagtggtcat tattttgcaa atatggaaga
     7201 aatggattgg aaaaacctag aaaaattaat tactaaagaa aataatatta tgcaggaatc
     7261 tgtatagttt tttaagggta attattaaaa tatatgagta acaacagata cttaaatagg
     7321 cataaaaaaa taaagggtat aataaggata tagaataaaa ataaatgata tagcacaaag
     7381 aggctgtctc aaaatacaga taagcctctt tttattgttg aaatgataag aatatattca
     7441 attttataca attttataca aacatactac gccaacttac ccatttcata tgcctgtttc
     7501 attgccttac ttcccttaat atcacctaca ttccaagcac ctacaccata tactatacct
     7561 ttttccttag aaccatttag acatgatgta aatcctctaa atccttctat tgttctttcc
     7621 atatcagcca cattttcatc tgctgctgta acgataaaat agaaatcttt atcacaaatt
     7681 tcagtatatc tagagcaagt tctatcaatc atagttttca tttgtgcatt catagtataa
     7741 aaataaactg gagtcgctaa aacaatcaca tctgccccaa tcattttttc aagaatttct
     7801 cccatgtcat ctgtctgtga acaatttgct tctttttcat aacaagcacc acatccagta
     7861 caatagttaa tatctttatc ttttaaaaat atcttctcca cttgattttt agattctaat
     7921 accccttgta taaactggtc acacaataaa tcagaatttc caccttttct aggactagct
     7981 gatactatta atacattttt actcataaga tactgcctcc attttcttat ttctactgct
     8041 ctttaatact ttttctttct caataatacc ttcttcatat ctatcaatct taaaatttaa
     8101 tcgttccaaa gttttttgca tttcttctat tctttttgct agttggtttc tctgctctat
     8161 taaaagttct tttctagctt tgatagtact gctcccttgt tgaaacatag ctacatactc
     8221 aattaatgtc tcaatagaaa gacctgcacc tctcatacac tttatgaaat taacccactc
     8281 acaatcttct tctgtaaaag acctaattcc acttttattt ctatttacag gtggtattaa
     8341 accaattcgt tcataatatc gtaaagtatc cgctgaaagc tcgtattttt tactaacttc
     8401 tgaaatcgtc atacatatct tctcctcttg atattgtata gattgaatta tttctcaaag
     8461 gtttctgcta cattctttaa agcatctata attttaatgt gttgaggaca gctttcttca
     8521 cattgtttac attcaataca atctgaggcc tttccataag ttttagtata attattatag
     8581 tagaccatct gtgttgaaaa tccagtatta agagcttgtt tttctgcatt gtacaacgca
     8641 aaatagtttg gaatagcgat attttttgga cagccttcta cacaatactg acaggcagta
     8701 caaggaatta aaattgattc gttgataatc tctactgctt catctataat attatattcc
     8761 tcttgtacga atggtttgaa attttgcata tatcctgtat tgtctaataa ttgttccata
     8821 tttgacatcc cacttaagac catcataaca ttatctttac ttgctgcaaa acgtattgcc
     8881 caagatgaaa ttgacatatc tggattgtag tcattcaata atttctctgc tttttctggt
     8941 atctttgcaa gtgtacctcc ttttactggc tccataacaa ttacaggctt attatgcttc
     9001 tctgccacct cgtagcattt tctagattgt atgctttcat tatcccaatc taaataatta
     9061 atctgtaatt gcacgaagtc tacttctgga tgctcactca agactttatc caataattct
     9121 gcactatcat gaaaagaaaa accaatattc tttatttttc cttctttttt cttttcttca
     9181 ataaacttaa agctatcaaa ttttttagct acttcgtaat gtgacacgcc tatattgtgt
     9241 aaaagatagt agtcaaaata gtctacacca catttttcta attgctcatt aaaaatggtt
     9301 tcttgctctt cttttttctt taaagccatt aatggaagtt ttgtagctat agtaaaactc
     9361 tctcttttgt gtctttttac tagagattct ctaagtgcta tctcactttt tcccatgtga
     9421 tacacatagg ccgtatcaaa atatgtaaat cccctttcta gaaaagtgtc taccatttta
     9481 tttaaatgtt ccatatcaat agttgtaaca tcattttcat cttttattgg taaacgcatt
     9541 aatccaaatc ctaatttttt tgcctccatt gctttacttc cccctttaaa acttgtttgt
     9601 tttttctctc tactttaact attcttacaa gtatataatt cttgtataat tatactttac
     9661 tacttggagt taacttcaag tcaatagatt tttttatttt taagacaaat attataaaaa
     9721 tacagttctt taatattaat ccattacatg tttctttcac cctccaattc tcaaacttca
     9781 caaactccaa catgtaaaga aatatatact ttaagaaatt cagtccatta atattactac
     9841 aaatactttt tagatatgtt taaaaagaaa tttcacctaa aagatttaga aaagatttag
     9901 aaataggtct tgtgtctatt ttaaaatata taaaacagtg gtaaagactt atttataaga
     9961 taaaaaatga atagtgtata ccctttttaa aaagtttttt cctttttata tttgtgatac
    10021 aatgttaaat ataaaaagga aaattttgta ttaaagaaat cttatttgtt gattttgtaa
    10081 cttcaaactc agcatcaatt tgattttaag attatatttt attaagtatg ctaaataaca
    10141 aatttttaaa gattgtgagg taaaaatatg aataagaaaa atttagctat attaatatca
    10201 ggtatgatgt ttttttctag ttcttcagca atttttgcag acaatactac aaagcaagaa
    10261 agattaatag gtaaaacaag atatgaaaca gcagtagaag taagtaaatt gggatgggtt
    10321 caatcaaaaa cagccattat agttaatggt aattctattc aaagtgcgct ttgtgcaaat
    10381 ccatttgcta agctaaagaa tgcacctata cttttagtaa acaacaacag tattgaaaat
    10441 tcaactaagg ctgagcttaa aaggcttggt gtagataatg tgtacattgt agatagtgga
    10501 aatagcattt cttctaaagt agaaaatgaa ataaaatcac ttaacataaa aataaataaa
    10561 atagtaggaa acaatatata tgaaatgtct acaaatgtac ttaaagaaat agataagata
    10621 aaaaaggtag aaaatgttgc agttgtaaat ggactaaagg gactatctga tgcagttagt
    10681 atagcttctc cagcagcaat acataatatg cctataatat tagtatcaga tgaaaacagc
    10741 aatgatagta gtataaattt cttaaacaat aggtctataa aaaaatctta catagttgga
    10801 ggaaataaga ttttatcaga caatacagta aagaaatatc caaacagaga aagaatcagt
    10861 ggttcagata gaaacaatac taatgcaaaa attattgata aattttataa agataaaaaa
    10921 ataaataatg tatttgtagc taaagatggt attaaccaag aaaatgcatt agtagattca
    10981 ttatcaatag gagtactagc tgctaaagaa aattctccta taatgatatc taatggtagc
    11041 cttgtaaata gtcaaaaaga atttattaaa aataaagata tagatgaaat aacacaagta
    11101 ggaggaggat ataatcaaaa agcatttgaa gatattttaa aactaaaaaa tgtgaacata
    11161 agaaataaaa ctaaaaaaat atctttaata caggctaaag aaatattaaa acaagctctt
    11221 ccaggaagca atattttagt ttgttattat gatgaagatg ataatgaata tgactgcaaa
    11281 gttataaagg ataatatcct atatgagata gaaattgatg cctactctgg taaaataata
    11341 gaaattgaaa aagatgatga cttaaatgat aataatttag gtacacaaaa tatatcattg
    11401 gataaagcta aatctatagc attagatgcc attcctaatg gtaatttaat ctattgtaaa
    11461 tatgatgctg aagataacga atatgaggct aaagtaataa aaaataagaa aacatatgaa
    11521 ttagagataa gtgcatttga tggaagaatt gtagatattg acatggacaa tgattctgat
    11581 gatgactttg atgataatga taagaataac tctaatacta atgacaacag ttctattatt
    11641 agtgctgaaa aagctaaatc aataatgcta gataaagtgc ctggtgggaa aatagtaaaa
    11701 tttaagtatg atgaagatga caaagaatat gaaggtgaaa taataaaagg aaaaactgaa
    11761 tatgagataa caattaatgc aattactggt aaaatattag aatttgaaat agatgattaa
    11821 taaaaaatat atattctatt aattattaca agcaataaag ccataaatat tgaaattttc
    11881 aatatttatg gctttatttt atttttttaa tttaaatcca cattatgcca ttatatatat
    11941 ctatgcactc ttgtaaaatg ggttatattt ctccagtata ttaaaaaaag tgagtgtctc
    12001 aaaataaatc ttctaactca taaagcactc tcctttgtat taaatcaaat atattttcat
    12061 catttaaaca attaagaaga gacttctctc tattttgaga caactccatt ttaatacact
    12121 atttatacat aaacatattt taaacaacta aaaagcaact aatatcttaa taaatatctc
    12181 aatacatatc ttcataacac atatcaccat aattacaagc agataaagaa ctctcctcat
    12241 ttaaatacga ctcaaattca tacccaaaca gaattgttgg ttctatatat atttccatat
    12301 ctgtatatct ccatcttctt acctttgcct ctataacctt gtaaaaatct tctaaactat
    12361 acccttcttt taatctttta tctataagtg ccttagttat actcaaatca gctttaaaat
    12421 tttttcctga ttcactattt aattttctta taataatttc atgtatgctt tctggatttt
    12481 tgtaagtaga atcttcagtc aaatcttcat ccgaattttc aaaggtattt ttatttaaat
    12541 tctttttatt taaattattt tttaataatt cttttttctt tgtctcattt tctgtttcat
    12601 acccagtatg aattatcaaa tcataatctt tgtctatact ctcttgattt atacggctgt
    12661 atatgttggt attactgttc ttaaacaact catttctatg tttatatttc attgtttttt
    12721 ggttattgtt aatagttgca tcaatgtatt tctctatatt tttgaaaata tcaccattct
    12781 ttgttacaat ttctgcatta ctactttcag aacaaacata actatataca gaacaacaat
    12841 ttccctttac tcccctactt attaatctca atatacctaa atctataaat tcatttacaa
    12901 gtctacttat tgtagatata gatacatcaa ggtcagatgc agctttcctt actgtcatca
    12961 taaattgtcc tcttggcaga gttcctttta atctttgtat attttctttt ctcattacat
    13021 agtgattaaa ccttattcta tttacatctc ttttttcatt aaaatataat actgctgaat
    13081 ttaattgata aaaactatta ctcatattcc cactcctcca atttaaatag ataatttgtt
    13141 gtaaagtttt tagatttttt aataacttat taaatgatta tttttattaa aaagtattct
    13201 ttgatatttt cattttaaag ttttaagtat
//
LOCUS       DAMKNB010000091        13139 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.097, whole genome shotgun sequence.
ACCESSION   DAMKNB010000091 DAMKNB010000000
VERSION     DAMKNB010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 13139)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13139)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13139
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.097"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            147..1484
                     /locus_tag="PC494_003032"
     CDS             147..1484
                     /locus_tag="PC494_003032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HDF3913513.1"
                     /translation="MGTYSLISTSINFILILINIFIAFFLYTLTSYFIDFRNHWIFKI
                     ILILGYSIISQMIIWLSEPVNILFTLFGYFILLIICSKSKLIPIISVVMILYPIIIGL
                     NFLFINNPIYEELIHSKEYILILSIVQIISALIKLLFWFLIHIFLKNRLVNIKQYLSN
                     KIWIFIDMVCISSFLSILIAIILPPTNLIPMGSNKNIILGNLPYGTYLIILSAILANI
                     GVILLLQPLIENVKMKIEKQANHLKEKYYNLLENQQIQIRKMRHDMNNHFQMIESYLE
                     IEDIAGAKKYFNQLKIGIGTLSGKQFCKNQALNSILNLRHTSLEENGVDVHFNIDIDN
                     HLGIEPIDLCTIFSNSLDNAIEASLKIPDLSNRKVVLKARCEKEYFSYLLTNNKVNPI
                     NRKQELFISDKKDSNSHGYGIENIREIVNKYNGKLDISYTESEFSLFLYIRLF"
     gene            complement(1820..2389)
                     /locus_tag="PC494_003033"
     CDS             complement(1820..2389)
                     /locus_tag="PC494_003033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GrpB family protein"
                     /protein_id="HDF3913514.1"
                     /translation="MKKKLEDMTLEELWNLFPIFLTTHKECWKNWFKEEQYRLTGILP
                     MQKIVRISHIGSTSVSTIYAKPIVDILIEIIPDYNMKDIKDLIESNGYICMSESSSRL
                     SLNKGYTVDGFEERVFHLHIRYVGDNDELFFRDYLIDHPDVAKEYEKLKLDLWKKYEH
                     NRDAYTDSKLDFVREFTEKAKVLYSNRYN"
     gene            2792..3364
                     /locus_tag="PC494_003034"
     CDS             2792..3364
                     /locus_tag="PC494_003034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="urea carboxylase-associated family protein"
                     /protein_id="HDF3913515.1"
                     /translation="MEYIINPCSGIKIKITRGQKIKIVDIEGGQVVDFFAEMKDDSTE
                     FISPGVTIDCNESLRLQVGNLIYSNKYRPMFKILYDDVREHDLLHPCCRPEMYDFFYH
                     NGENHPNCFDNINRTLGTSHQIIHPINFFMYTKVNTDGSIEVCEPLSKASDKIILEAL
                     ENMTLGIAACSVSESSCNSRKCTSIKILVD"
     gene            complement(4043..4945)
                     /locus_tag="PC494_003035"
     CDS             complement(4043..4945)
                     /locus_tag="PC494_003035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HDF3913516.1"
                     /translation="MLPQDYYGLIVILGVILGVMGAFYNWFTLYVQSLYKKIPKIGTF
                     GKLLIPFIMAGILGLVMPDVLGSGHNLVEELTSHKYIFGMVVLIFVIRFIFSAVSFGS
                     GAPGGIFFPLLVLGAFIGGIFGMVGVKVFGMNPDYVNNFVLLAMAGYFTAIVRAPLTG
                     IILIFEMTGSVSQMLSLSVISIVAYIVATLMKSKPIYESLLERLLEKNGEPVHKERGE
                     KILDQFSVMFGSPVANKAIQDVQWPENCLLVAIQRGGEEIIPRGKTILRPSDVIVTMT
                     DERDSGAVYDKMENLCKEHTAHIF"
     gene            complement(5072..5191)
                     /locus_tag="PC494_003036"
                     /pseudo
     CDS             complement(5072..5191)
                     /locus_tag="PC494_003036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888399.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(5738..6400)
                     /locus_tag="PC494_003037"
                     /pseudo
     CDS             complement(5738..6400)
                     /locus_tag="PC494_003037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016440163.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
     gene            complement(6560..7096)
                     /locus_tag="PC494_003038"
     CDS             complement(6560..7096)
                     /locus_tag="PC494_003038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GrpB family protein"
                     /protein_id="HDF3913517.1"
                     /translation="MIGLKCGMVKLLEHQMIWDKSAKDVIILLKSIWDKTAIDIQHIG
                     STSIPSISAKPIIDIVVGVASLEEAKLYLERLEQCGIVFRGQDVPKQLLFAMGDFEKN
                     TRTHHIHVVEWNSVAWNNYINFRDYLNTFTDKAKLYDSHKQKLALQFEDNRKIYTQRK
                     QELINILLEEARLWRINT"
     gene            complement(7169..7582)
                     /locus_tag="PC494_003039"
     CDS             complement(7169..7582)
                     /locus_tag="PC494_003039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003507530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3795 domain-containing protein"
                     /protein_id="HDF3913518.1"
                     /translation="MKMPKESIDTIMFAPCGMNCMVCYKHCYHKKPCAGCLNGDTGKP
                     EHCRKCKIKDCVCQKGLFYCFECFNFPCKLIKNLEKSYNKRYQASLMENSKFVQQYGL
                     EKFMQKQKERYTCSKCGGIISIHDRECSECQEKVK"
     gene            8075..8713
                     /locus_tag="PC494_003040"
     CDS             8075..8713
                     /locus_tag="PC494_003040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid stabilization protein"
                     /protein_id="HDF3913519.1"
                     /translation="MDEKILELLQEMQGNISNMQGSISGIEGTISDMQSNINGIEGTI
                     SDMQSNINGIEGTISSMQGNINGIENTISGMQGTIGDMQGSISGMNGTISDMQGSISS
                     MDGTINSMQGSITDMQVEIKEVNSRLDNMEPDIKDLKTGQVETSSRLDTIQSDVTEIK
                     SDVKINRNTLDTVIKHTSSLVKDTSDIKNDLNNIEIVTSKNSNDIAKLKSVK"
     gene            complement(9321..9500)
                     /locus_tag="PC494_003041"
     CDS             complement(9321..9500)
                     /locus_tag="PC494_003041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HDF3913520.1"
                     /translation="MLQTGKQGADKKYLDNMFFVKGYVEELLFLDKSYDIVFSCIVFH
                     HCTNVQNIFCIFWKW"
     gene            complement(9726..10259)
                     /locus_tag="PC494_003042"
     CDS             complement(9726..10259)
                     /locus_tag="PC494_003042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HDF3913521.1"
                     /translation="MQYISYYHSPIGNILLASDNIGLTGLWFENQKYYAYNLDQEHQE
                     KELPIFEQTKKWLDIYFSGKEPNFTPSLHMVGTPFQTTVWKILQQIPYGKTITYGEIA
                     YKVAQQKGISKMSAQAIGGAVGHNGISIIVPCHRVVGTNGSLTGYAGGIDRKIKLLSL
                     EKVSVQHYFIPKKGSAL"
     gene            10576..10926
                     /locus_tag="PC494_003043"
     CDS             10576..10926
                     /locus_tag="PC494_003043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3913522.1"
                     /translation="MGKVRIGCKKEKYFYVRNPVKSLVDRITENEQFAIYHFTHKYNW
                     RNKVFSILQRLIRLEKSKNELYMYEALVSVSFLWLIMIKNIVLPPIKHKNIINIHMQK
                     ILRYIEKYYCFTLY"
     gene            complement(11802..12374)
                     /locus_tag="PC494_003044"
     CDS             complement(11802..12374)
                     /locus_tag="PC494_003044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese catalase family protein"
                     /protein_id="HDF3913523.1"
                     /translation="MWIYQKTLEHPVNIRQADPRMAKYIMTQLGGPNGELAAATRYLQ
                     QRYTMPTGKSRALLTDIGTEEMAHVEIISSVLYQLIGNCTPEELKAAGLGSNYANFGH
                     GLQPVDSNGVNFTTSYINVFGDSVTDLHEDMAAEQKALATYYQLINLTDDPDLKDILR
                     FLGEREVVHYQRFGEALMDVYEFTECKHQF"
     gene            complement(12436..12699)
                     /locus_tag="PC494_003045"
     CDS             complement(12436..12699)
                     /locus_tag="PC494_003045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore coat protein CotJB"
                     /protein_id="HDF3913524.1"
                     /translation="MSLNRRELLERISEYQFACIELNLYLDNNPRDKKALDSYNRYCD
                     KFTQAVCDYESKYGALTNFGYESSEYPWSWISEPWPWDKSFYK"
     gene            complement(12699..12920)
                     /locus_tag="PC494_003046"
     CDS             complement(12699..12920)
                     /locus_tag="PC494_003046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore coat associated protein CotJA"
                     /protein_id="HDF3913525.1"
                     /translation="MGYLKEDKQDYCCEFARPYINRQIYDDTYNPKTALKRGTLFPEL
                     DLIESNNYNDWLYANPKNRVRAKKGGNMY"
BASE COUNT         4610 a         2219 c         1569 g         4741 t
ORIGIN      
        1 aaaactcaat tttttgaagc ttaatttcta gaattttatt tttcaaaatc aattctttga
       61 aatctaattt ccagaatttt aatttttaag atttaatttt ttaaaactta gtttccagaa
      121 tcttaattaa tagaaaggta tattaaatgg gcacttattc tttaatctct acaagcataa
      181 attttattct aatattaatc aatattttca tagccttttt tctttatacg ttgacttcct
      241 attttataga ctttaggaat cattggattt tcaaaatcat attgattttg ggctactcta
      301 ttattagtca aatgataata tggctttccg aacccgtaaa tattttgttt acactattcg
      361 gatattttat actacttata atatgtagca aaagcaaatt aattcctata atatcagttg
      421 tcatgatact ttatcctatt ataattgggc ttaattttct ttttataaac aaccctatat
      481 atgaggaact tatacactca aaagagtata ttttaatact ttcaatagtc cagataattt
      541 ctgctctaat taaattatta ttttggtttt taatacatat tttcctaaag aatagattgg
      601 tcaatataaa acaatactta tcaaataaaa tatggatttt tattgatatg gtatgtatat
      661 cttcattttt atcaatatta attgctatta ttctgccacc tactaattta atccctatgg
      721 gtagtaataa gaatattatc ttaggcaact taccttatgg cacttatcta atcatcttgt
      781 cagcaattct ggcaaatatc ggtgtgatac ttcttttaca gccattgatt gaaaatgtaa
      841 agatgaagat agaaaaacaa gcaaatcacc taaaagaaaa atactataac ttactagaaa
      901 atcaacaaat tcaaatacgc aaaatgcgac atgatatgaa taatcacttt caaatgattg
      961 aatcgtattt agaaattgaa gatattgctg gagctaaaaa gtattttaat cagttaaaaa
     1021 taggtatagg tactcttagt ggcaaacaat tttgcaaaaa ccaagctctt aactcaattt
     1081 taaatcttcg tcatacaagt ttggaagaaa atggtgttga tgtgcacttt aatatagata
     1141 tagacaatca cttgggtata gaacctatag atttatgtac tattttttca aattctttag
     1201 ataacgctat agaagcatct ttgaaaattc ctgatttgtc aaatagaaaa gtggtattaa
     1261 aggcacgttg tgagaaggag tattttagct atttattgac aaacaacaaa gtaaatccta
     1321 tcaatagaaa acaagaacta tttatttcag ataaaaaaga tagtaattct cacggatatg
     1381 gtattgagaa tattagagaa attgttaata agtacaatgg aaaattggat atttcttata
     1441 ctgagagtga attttcttta tttctttata ttagattatt ttagtctaaa attagattat
     1501 cttatataat acaaattaga ttgtttgata ctatgtaaaa ttataataac ttataattaa
     1561 atatttacac atatattcat taacttaaaa tttaatcaaa tgtgatattt tatttacctt
     1621 agtaaaaatg tgtgtgtctc aaaataaact ttttagttga tgaggcactc ttttttacat
     1681 gaaatcaaat atatttttat cctttcaaca atgaaaaagg gatttatctc tccattttga
     1741 aacaagccct ttttctatta attactttct taaaaaatat aatacgatat ataagataaa
     1801 tatctaattg tacctatttc taattatatc tattagaata caacaccttt gccttttcag
     1861 taaactccct aacaaaatct agtttactat ctgtataagc atcacgatta tgctcatact
     1921 tcttccaaag gtccaactta agtttttcat actcctttgc aacatctggg tggtcaatta
     1981 agtaatctct aaaaaacaac tcatcattat cacctacata ccttatatgc aaatgaaaaa
     2041 ctcgttcttc aaacccatct actgtatacc ctttattaag tgaaagccta ctactgctct
     2101 cagacataca aatatatcca ttcgactcaa tcaaatcttt aatatctttc atattataat
     2161 caggaattat ctcaatcagt atgtcaacaa tgggcttggc ataaatcgta ctcacagaag
     2221 tacttccaat atgacttatt ctaacaattt tttgcattgg caatattcca gttagtctat
     2281 attgttcttc tttaaaccaa tttttccaac attctttgtg agtagtcaaa aatataggaa
     2341 acaagttcca taactcctct aaagtcatat cttccaactt ctttttcatt agttacctcc
     2401 ctttaaattt gtactttata ttttttcttt ttcaaattta cttagttaat atttaacttt
     2461 attttttatc aaatcatttt tctaattatg taaatttttc taaatttagt ttttaatgta
     2521 ttataacaga tttttaccct tcttacactt ttgtatctat ttaaatatta gaacattttt
     2581 tcttacttct aaatacagta agattgctta aataccaaat aggagcaaaa aaactctgta
     2641 atcttaaaaa aactacaaca tctttatgag aattaaaaaa tgatagacta tgttatcaac
     2701 attaagaaac agatagaaaa gaaacagagt atgtgctaaa atgggaacat agaacagaat
     2761 gacaaattgg aatttatgga ggacattaaa tatggagtat ataatcaatc cttgtagtgg
     2821 tataaaaatt aaaataacta gagggcagaa aattaaaatt gtggatattg aaggaggaca
     2881 ggtcgttgat ttttttgcag aaatgaaaga tgattcaact gaatttatat ctccaggtgt
     2941 tacaattgat tgtaatgagt cattaagatt acaagttggg aatttaatat attctaataa
     3001 gtatagacct atgtttaaaa ttttatatga tgatgtaagg gaacatgact tgctacatcc
     3061 atgttgtaga cctgagatgt acgatttctt ttatcacaat ggagaaaatc atccaaactg
     3121 ttttgataat attaatcgca cacttggaac ttcccatcaa attattcacc ccattaattt
     3181 ttttatgtac acaaaagtca atacagatgg gagtattgaa gtatgtgaac ctttatcaaa
     3241 agccagtgac aaaattattc ttgaagcatt ggaaaacatg actttaggga ttgctgcatg
     3301 cagtgtttca gaaagttctt gtaatagcag aaaatgtact tctattaaga ttttggttga
     3361 ttgacaaatt tcatttatcg aaaaaatatc aaaattaaaa aatgacgtca aaggcgcaaa
     3421 agggtaacca cttgcgctct caattcatta tggtttgtta cgtatttatg ggtaaaaatc
     3481 ccttgattct atgatgtttt tcagacacaa ttacaaatga gtaaggattt tatactcata
     3541 ctctaaaaaa tagcatttta ttgcgtaaca gaacgaaaaa acagtgtgta cctttttctt
     3601 gcaatacaca ctgtattcat agccactcta gctgttaact gttaattatc tcataatacc
     3661 cttactggta ttcatctaat cttaacccct tttaattatt ttcatttata aataaattct
     3721 attcttccca aaatatcgta attaaaatat attaattaaa atatcccaat aagaatatct
     3781 gaaaaatctt ctacctattt tttcaaacct tttattccca ttcctcatac aatagtgcaa
     3841 cttttagcac agtataaata taccattagt ccatataatc tcattaacaa atatatacaa
     3901 ttattttctt caaactcttt tatatctaag atatcacatt ttcattttct tatattaatt
     3961 ccttaactct ctttcaaatt accaattttt taatcaaatc ttcattaaat attctatcat
     4021 tattaaacat tcatcattat ccctaaaaaa tatgtgccgt atgttcttta cacaaatttt
     4081 ccatcttatc atacacagca ccactatctc tctcatctgt catagtcaca attacatcac
     4141 ttggtctaag aattgtctta cctctaggaa taatttcttc tccacctctt tgaattgcta
     4201 ccaaaagaca attttcaggc cactgtacat cctgaattgc cttgttcgca acaggagagc
     4261 caaacataac agagaactgg tctagtatct tttcgcccct ctctttatgt acaggttctc
     4321 cattcttttc aagtaacctc tcaagaagac tttcataaat aggtttagac ttcataagtg
     4381 tagccacaat atatgccaca attgaaatta ctgatagtga aagcatttga ctaacagaac
     4441 ctgtcatttc aaaaattaat atgataccag tcaaaggggc acgcacaata gctgtaaaat
     4501 atcctgccat agccaaaagc acaaagttat ttacataatc gggattcatt ccaaaaactt
     4561 taacacctac cataccaaat attccaccta taaatgctcc taaaacaagc aatggaaaaa
     4621 atattccccc tggtgcacct gacccaaaac taacagccga aaatataaaa cgtataacaa
     4681 aaatcaaaac aaccattcca aaaatatatt tatgacttgt aagttcttca actaaattgt
     4741 gtccactccc cagaacatca ggcataacaa gcccaagaat accagccatt ataaatggaa
     4801 tcaacagttt tccaaacgta ccaattttag gaatcttctt gtataaagac tgcacatata
     4861 gagtaaacca gttgtaaaat gcccccataa ctccaagaat aacacctaaa atcactatta
     4921 atccataata atcttgtggc aacacatttc caatctgaac ctcccatgac taaagtcaca
     4981 gggttcctgc ttcatagaat tttgcatact aaaatatgtc ttactaattc tccacaggct
     5041 atccccgtag ttcctacggt tcttacataa gttatttatt ttgaattgtt attagtctta
     5101 atccttcttt taatatattt atacttgcat ttatatctct atcgtgagtt tcattacaac
     5161 taggacaaat ccattctctt ataataatgt taacaaatgt aattatttaa aacaattatt
     5221 tagaaggttt tatatttaat tttaaataac atatttaaga accgtaagtc ttaactttta
     5281 tcatttttga ggttgtcgtt cacataagtt cgctactacc tatgcagttc tcttatgaac
     5341 ttcttacact ttcatgtaag cacagactat atcttatcct tcggcattat ccgctaaggt
     5401 ctacccactt ccactaccaa tagcttgtag tgtacttccc tcaagaggaa tagtcgttga
     5461 agtttctcct attcggagct tacctgctga ttgcccattt ttaaagtact tagggtttaa
     5521 ccttatacca tctaaccaat tttttctact ttcgtaactt tcacacttag gtttatttca
     5581 tccttatgtt ttagtttggt tagctttagg ggtttccagc aattcaagta gtattggata
     5641 ggttctatcc tatctctaca tataggtttc cctatatgct gactatttta gctactaact
     5701 catgactaaa gtcacaagtg ttcgtagcta ttttttaatc aaactggaat acagactcca
     5761 ttcctaggaa attggctgaa atatagtctg ctgtcaaaga tgctgtcatc acagaaatta
     5821 aaacagatac tgaaaagttt ttatggactt cttcaagtga aaacataaca cccgctagtg
     5881 gtgcatgaaa ggctgctgat aatccagcac ttgccccaca ggttaacagg aatttttcct
     5941 ctgtcttccc tcggtcaaga gctctagaaa tacctttacc tgccatagca ccaagctgaa
     6001 tggaaggacc ttcccttccc aaagcaagac cacccatgag tgataagaat cctccaataa
     6061 attttgttgg caacactcgc caccatactt gttttatttt ccctgtcatt tccccctcaa
     6121 gctgagggat accacttcca gaaatcattg gctcccagtc caccaacttt gatacaatcc
     6181 acgcaagtac tgcaagtact gcaaaccaag ctattatttt tattgtagaa ccttctacaa
     6241 attttaaaat ttggctaagc caagtaccag cctgccctaa aagtatcctg tataaaagca
     6301 caatcaaacc agccacagcc ccaaccataa gtccttcacc aatcaaaatt acctgaaagt
     6361 gctctgcccg tttgataata tgagatgtat cctttttcat actgttcctc cttcatccaa
     6421 taattctaca caatctgaat ctccaatgac taaagtcatg agtgtgtaca gatatttttt
     6481 aatcaacaaa aatagatttt tatttactaa atataagaaa ataattgctc aatttctcaa
     6541 taaatgtgaa tttattcttt taggtattta ttctccacag tcgtgcttct tccagcaaaa
     6601 tatttattag ttcttgcttt ctctgtgtat agattttacg attgtcctca aactgtaatg
     6661 ctaatttttg tttatgacta tcatagagtt ttgctttgtc tgtaaaagta tttagataat
     6721 ctcgaaaatt gatataatta ttccatgcaa cactattcca ttcaacaaca tgaatatggt
     6781 gagtacgagt atttttctca aaatctccca tagcaaaaag taattgtttt ggtacatcct
     6841 gacctcgaaa aacgattcca cattgctcta acctttcgag gtataattta gcttcctcta
     6901 aagaagcaac acctacaaca atatcaataa taggctttgc gctaatactg ggaatagaag
     6961 tgcttccaat gtgttgaata tcaatggcag tcttatccca tatacttttc aataatataa
     7021 tgacatcttt tgcactttta tcccatatca tctgatgttc caataattta accataccac
     7081 attttaaacc tatcactata taccacctca atataatcca cctttatata tattacaatt
     7141 ttttctatct tgataaacag tgatttagct atttcacttt ttcttgacac tcgctacatt
     7201 ccctatcatg aatagatata attcctccac atttagaaca agtatatctc tccttctgct
     7261 tttgcataaa cttctctaaa ccgtactgct gaacaaattt actattttcc ataaggcttg
     7321 cttgatatct cttgttataa cttttttcaa gattttttat gagtttacaa ggaaaattga
     7381 aacattcaaa acaataaaac aacccttttt gacagacaca atcctttatt ttacacttac
     7441 ggcagtgttc tggctttcct gtatcgccat tcaaacaacc agcacatggc tttttgtgat
     7501 aacaatgctt atagcaaacc atacaattca ttccacaagg agcaaacata atcgtatcaa
     7561 tactctcttt tggcattttc ataacatttt actcctttca aaaatccaat ttgtcgaatt
     7621 gttatatatt catattgtaa cataaaaaat agctaaaaaa ttcatgcact ttcattgcca
     7681 ataaattttc aaggaaatat gaaagtttaa aactaagaat aaaaagagat aaaaaggaag
     7741 ctactaatca aaatattcaa atacaagtaa tcaatataaa taacttaagg tatatttaaa
     7801 agtatatgat attaccagca gttttaaata caaatataac cacacatgcc tcaaaaacac
     7861 ttattacagt atcttagaaa cttagacaat acataagatt cattaataaa aaagttctca
     7921 atatagtcat taataaaaac gttctcaata tagatatatt taaccatgtt ttgaatagca
     7981 gataattata tgattaaaaa ttaaatatga catagcgttt gtggaatata acacctaaat
     8041 tatgttataa taataaaaca ggagtgtgat agtgatggat gaaaaaatat tagagttatt
     8101 acaggaaatg caaggtaata ttagtaatat gcaaggtagt atcagtggta tcgaaggcac
     8161 tattagcgat atgcaaagca atatcaatgg tatcgaaggc actattagcg atatgcaaag
     8221 caatatcaat ggtatcgaag gcactattag tagtatgcaa ggcaatatca atggtatcga
     8281 aaacactatt agtggcatgc aaggcactat tggcgatatg caaggtagta tcagtggtat
     8341 gaatggcact attagcgata tgcaaggcag tatcagtagt atggatggca ctattaatag
     8401 tatgcaaggc agtattactg atatgcaagt tgaaattaaa gaagtcaata gtaggttaga
     8461 caatatggaa cctgatatta aagacttaaa aactggacaa gttgaaacta gtagtagact
     8521 tgatactatt cagagtgatg ttacagaaat taagtcagat gtaaaaatta acagaaatac
     8581 attagataca gtgattaaac atacctcttc attagtaaaa gatacatcag atattaaaaa
     8641 tgatttaaat aatatagaga tagtcacatc taagaattcg aatgatattg ctaaattaaa
     8701 atcagttaaa taatatacta tagtaaaaaa tacctgaaaa tttcacatac ttctttaaag
     8761 ttataccaaa ttttatacag aaatactgat tatccgacaa cacactttac ttataaataa
     8821 tttattaaaa aaatactcat tttatcctaa aattaacacg actaaatgag tcttgatata
     8881 ataataaaaa ataagggaga ttggacacta aaaagttgtg tatctccctt atattctata
     8941 atatagttat ataatttttc agcctaaaat aaaagtccat ctttgattaa aacacatccc
     9001 cttatcactt ataaaaggat aaaatcttgt tttcattttt ccatttatat cttcttgctt
     9061 aagagtaata attttttctt ttgatacttt aagtgtttgg ttaaatttaa ccaatcgact
     9121 aagttttgtt caatatctat ttttcatatt ttccaatact taatctattt tttataaata
     9181 attctttcat ttctaactca cttacatttt ttacataaaa cgaaacatat aaatttcaac
     9241 cttatcttgt atggttctta atacttaatg agtagcttaa gtatcaatca ttataaattt
     9301 ttcccttaca tttaacactc ttaccatttc caaaatatac aaaatatatt ttgaacattt
     9361 gtacaatgat gaaatacaat acatgaaaat acaatatcat aactcttgtc taaaaataga
     9421 agttcttcaa cataaccttt cacaaaaaac atattatcta agtatttttt gtctgctcct
     9481 tgttttcctg tttgtagcat ataaattact gcatctaaac atataactac tcacacgaaa
     9541 aaagaaaata aacttccaaa atacaagctc taaaaactac ctctaaagtt gtataatgtt
     9601 tactaggaat aaggttgtat aacatatagt ttaaataatc attttttaaa attgcaagtt
     9661 attgctttca aaattagatg tttttatatc aaataaatga ttaagaattt ctaaatttaa
     9721 tggctttata atgcactccc tttctttggg ataaaataat gttgcacaga tactttttct
     9781 aaagataaca attttatttt tctatcaatt ccaccagcat acccagtcaa actcccattt
     9841 gttcctacaa cacgatgaca tggaacaata atagagattc cattatgccc tactgcacca
     9901 ccgattgctt gtgctgacat tttagatatt cctttttgtt gagcaacttt atatgcaatt
     9961 tctccataag tgattgtttt accatatggt atttgttgta aaattttcca cactgtagtc
    10021 tgaaaaggag tacctaccat atggagtgat ggtgtaaaat tgggttcttt tcccgaaaaa
    10081 taaatatcta accatttctt tgtctgctcg aaaattggca attctttttc ttgatgttct
    10141 tggtcaagat tataagcata atacttttga ttctcaaacc aaagaccagt taacccaata
    10201 ttatctgatg ctaaaagaat atttccaatt ggactatggt aatagctaat atattgcata
    10261 caattcctcc ttatattctg aaaacttcac tcaaatcatt agacacttct tttctatcta
    10321 ccattatgta aaaacatact aatataattt ccttctaact acactttcgt tataatatct
    10381 atcctcatat catattagtt ttatatttac ctgcatctgt tcatcctttt ttccctttcc
    10441 ctttgatgaa tataaaattc atacatttaa gcttcctact gtattaactt ttatagaagt
    10501 gtatattata attttatcac caaatagacc aaaaaaatat cgatataaca tcaagtaata
    10561 tcataatact ttcaaatggg aaaagtaaga ataggctgta aaaaagaaaa gtatttttat
    10621 gttagaaatc cagtaaaatc gttagtagat agaataacag aaaacgaaca atttgctatt
    10681 tatcatttta cacataaata taattggcgc aataaagtgt tttctattct acaacgatta
    10741 ataaggttag aaaaaagtaa aaatgaactg tatatgtatg aagcattagt ttctgtttct
    10801 ttcctttggc ttattatgat aaaaaatatt gttttgccac caataaaaca caaaaatata
    10861 attaatatcc atatgcaaaa aattttacgt tatattgaaa aatactattg ttttacatta
    10921 tattgaaggg tactattgtg aaaacttaat tttggagtac tatcaagcag tggtaatatc
    10981 aataaatcag agtgctccag atgatttgaa ctaagtttaa atactatacc ttataaatat
    11041 tttactgagt tttgtttatt aaaagcaact caatttctaa aaggcacaaa tgagctaata
    11101 agtgacattg ctataaaagt tgtttttcat caaataatct attttagtaa atgttttaaa
    11161 gaaaaaacgg gatattctcc aaaagtgtac agaaatataa aaaaagagat atgatttttt
    11221 atttcttttg attatccaaa gagtaaataa aaaatattgt aaaaaactta ctaacaacgg
    11281 caatgctttg aactatggta atactttgaa cttttgattg gacttttttt gctaaaataa
    11341 tatatttaaa tagcaaagta atctgtttaa tcaataaaaa ataagagata aaagaaatca
    11401 actaaaactt ttacctctta ttttgatagt ttatcagagc taatatttac actcttttta
    11461 tttttgatac ttcattaaaa atgatgctta ttctcttttc atttttaata cttcattaga
    11521 acttatgctt attctctttt cacttttaat tcttcattag aacttatgct tactctccat
    11581 tcacttttaa ttcttcatta ggactatgct tattctccat tcacttttaa ttcttcatta
    11641 aaaatgatgc ttattctcca ttcactttta attcttcatt aaaaatgatg cttattctcc
    11701 attcactttt gattcttcat taaaaatgat gcttattctc tgttcacttt taattcttta
    11761 ttaaaactga tgcttattct ccattcactt tcaattcttc attaaaactg atgcttgcac
    11821 tctgtaaact cataaacatc cattaatgct tcaccaaatc tttgatagtg aactacttcc
    11881 ctctcaccca aaaatctcaa tatatctttc aaatcagggt catcagttaa atttattaat
    11941 tgatagtacg tagccaatgc tttttgttca gcagccatat cctcatgtaa atcagttacc
    12001 gaatcgccaa agacattaat ataacttgta gtaaagttta ctccattaga atctactggc
    12061 tgaagaccat gtccaaaatt agcataatta ctaccaagtc cagcagcctt aagttcttct
    12121 ggagtacaat tgcctattaa ttgatataac actgaagaaa ttatctcaac atgagccatt
    12181 tcctctgtac ctatatcagt taaaagtgca cgagattttc cagttggcat agtatatctt
    12241 tgttgaagat atctagttgc agctgccaac tcaccattag gtcctcccaa ctgagtcatg
    12301 atatattttg ccattctagg gtctgcttgt cttatgttaa ctggatgttc cagtgttttt
    12361 tgataaatcc acatattatc ttactcctcc ttaatatata tttaataata aatctaattt
    12421 taaagtttaa taattttatt tataaaatga tttgtcccat ggccaaggtt cagatatcca
    12481 tgaccaagga tattcacttg attcatatcc aaaattagtt aatgctccat atttagattc
    12541 ataatcacac acagcttgtg taaatttatc gcagtatctg ttgtatgaat caagagcttt
    12601 cttatccctt ggattgttat ctaaatataa atttaattct atacaggcaa attgatattc
    12661 tgaaattctc tctaaaagtt ctcttctatt taatgacatt agtacatgtt accccctttt
    12721 ttagctctaa ctctattttt aggatttgca tatagccaat cattatagtt atttgactct
    12781 attaaatcta attcaggaaa taaagtacct ctttttaatg ctgtttttgg attgtatgtg
    12841 tcatcataaa tttgacgatt gatgtatggt ctagcaaatt cacaacaata gtcttgttta
    12901 tcctctttta aatatcccat taattatcct ccttaatttt tagaatttta aaatagcatt
    12961 atttttaaaa attgtatact ggttctatat tataactggt agttttaata ggtctttaat
    13021 aagattaaat gattaaataa gtatcttttt ttcttatttt acctctaaaa atttttctaa
    13081 ttagtctttc ataaatatct attttaaata aataatatag agtttataca attttttat
//
LOCUS       DAMKNB010000092        12963 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.098, whole genome shotgun sequence.
ACCESSION   DAMKNB010000092 DAMKNB010000000
VERSION     DAMKNB010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 12963)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12963)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12963
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.098"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            <1..681
                     /locus_tag="PC494_003047"
     CDS             <1..681
                     /locus_tag="PC494_003047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDF3913526.1"
                     /translation="RILNATISKEPSGRYYVSLCCTDVDIEAFENTNNHIGLDLGIKE
                     FCISSCGEFIENPKYLKKSLNKLAKLQRELSRKTIGSLNRNKARLEVAGLQEHIANQR
                     KDFLQKLSTKLIKENDIICIEDLQVKNMIRNRKLSRLISDVSWSEFIRQLEYKANWHG
                     RQIVKVGKFFASSQICNKCGYKNEEVKDLNIREWICPSCNETHDRDINASINILKEGL
                     RLITTQNK"
     gene            1236..2642
                     /locus_tag="PC494_003048"
     CDS             1236..2642
                     /locus_tag="PC494_003048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HDF3913527.1"
                     /translation="MNTGFPKDFLWGASSSAFQVEGAWDKDNKGKTVADYNSFKKSHL
                     QADTKVASDFYHNYEEDIELMKELGMKTYRFSISWARIIPDGEGEINQKGLDFYNKII
                     DKLIECDIEPFVTLYHFDLPFKLVEKYNGWESRETVYAFERFAKICFKHFGDRVKYWQ
                     PHNEQNLIVRVEERINIYDETDSWKIDKMRAQMDYNLCLAHALAVNACHEMIKESKIG
                     AAVSSSVTYPLTSKPEDVYAARMNDNFKVYYMLDMHHYGEYPGYYMKYLEKRNIVPHM
                     EDGDKEILKKAKMDFIAVNYYRTNCAEALPEDSQHPFGLREGTVDFSMYGLFKMSMNP
                     NLEASEYGAAIDPSGLRVALNEYWQRYHLPVIITENGLGAKDILEDGKIHDDYRIDYL
                     RSHINACKLAIEDGVEMIGYCPWSFTDLLSSSQGFNKRYGLVYINRTDHEVLDLKRIK
                     KDSFYWYKEVIENNGIVK"
     gene            2670..3518
                     /locus_tag="PC494_003049"
     CDS             2670..3518
                     /locus_tag="PC494_003049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HDF3913528.1"
                     /translation="MYITKVLNNSLLLAKDDNDEEIILMGKGIGHNYKAGSELNKKDI
                     EKIFVLHDENIKKSIIQLATEIDAEYFGIAQMIIAYGIEKYNLKLMNHIYLALTDHIA
                     FAVRRFKEGIMIENHYLFEIKEFNPKEYDIGKYAITVFKEVLGLDLPEEEIGNIAGHF
                     INAQQDNPYSDRNKRSAKIVNAILQIVHYHFSIVYNKESFYYRRFVMHLKAFSQRFLA
                     NEPSREKIDFIYEQVQKNCKEEYECVKKVGAYMYKEYSRELPRQEELYLMIHIHKILG
                     ELCENS"
     gene            4179..4871
                     /locus_tag="PC494_003050"
     CDS             4179..4871
                     /locus_tag="PC494_003050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003020373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF3913529.1"
                     /translation="MNKVLIIDDDKDLCILLKKSISIEQIEANYCHSGRDGLAELSKQ
                     DYQLVVLDVMMPGMDGFETMEQIRKYSSIPILMLTSKSDNYSKVHGLRAGADDYLTKP
                     FEITEFTARVLSLIRRYTRFNPKNEEPQQLSFKGLLIDLDQHTVTTNGEPMLLPPKEF
                     GVLLYCAKHQGKILTKQQIYEAVWGEPYVYDDSNIMAIISRLRKKIELDPSSPIYLQT
                     IKGIGYQFNTEV"
     gene            4868..5803
                     /locus_tag="PC494_003051"
     CDS             4868..5803
                     /locus_tag="PC494_003051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF3913530.1"
                     /translation="MKMDEQTIILFLLLLSIGLLFLSIFAFSKLGHIYKRLKDIEEIL
                     ADVQIGDENRKILIKPCDVMAPLVYQLNEIVYDYENKLLSLKKSDKASKQLMTSLSHD
                     VRTPLTTLIGYLDAVHSGIVIEQEREEYLEIARRRAYDLKDYIDVLFDWFRLNSDEFT
                     LSIESVEIAELSRNILKDWIPIFHEKKLNFEIDIPENRLMVNLDPDGYSRVVNNLVQN
                     VLAHSKARQIKITMSEDSRMVLLRVEDDGVGIARENLPHIFERLYKCDKGRSEKGSGL
                     GLSIVSQMVERMGGQISVESEIGKYTIFTVSLPLI"
     gene            5951..6874
                     /locus_tag="PC494_003052"
     CDS             5951..6874
                     /locus_tag="PC494_003052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013273760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF3913531.1"
                     /translation="MNNLIIETKNLTKQYGAQKSVSNLNIHVQKGRIYGLLGRNGAGK
                     TTTMKMLLGLTKPTTGEIKIFGQDIHNNEKKLLPRIGCLIESPGFYPNLTGTENLKIF
                     ARLRGIPKKNAVESALDVVGLPNNDKKLFSQYSLGMKQRLAIALAIMHDPQLLILDEP
                     INGLDPIGIAEVRTFIRDLCTERGKTILISSHILSEIALLADDIGIIDHGILLEEESL
                     AQLEEKNSKYIHFAVSDAAQAARLLETQLNLKNFKVADNYNIMLYDTDVSVAEINRAF
                     ILNNIEVSESHLCEDTLEDYFKKVTGGEGIA"
     gene            6858..7628
                     /locus_tag="PC494_003053"
     CDS             6858..7628
                     /locus_tag="PC494_003053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF3913532.1"
                     /translation="MKELLDIISCEFSKLKRLKFILISILGACLFPIPATILIAKDNL
                     PFEQLFKLVVNFGYFLLLPIVLSIVASQLFFIERDNDVLKNLATVPVQKGKLALAKLA
                     VLLFISLFYSVAGLGATIIGGFIVGIVEGVAVKLGMSIAFGIMFFVTVLPVVVLIVYF
                     NRSYIFSIILSFVYAIFNFSISLNIINFEPNNPILSVLPAPVIMRWWMAFWGDPTGEY
                     TALRQPYLLSTPACVGILCLITIIAVLLICMIYKKQEN"
     gene            7638..8420
                     /locus_tag="PC494_003054"
     CDS             7638..8420
                     /locus_tag="PC494_003054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF3913533.1"
                     /translation="MLDIITTEFQKIKRYNILWIGVVAVLFSALLAVFQVVSSHGSDP
                     LTYESFANGVIWNNFSLSFPFGITLIGGYLINREYTDQTLKNILTVPISLRKLLVGKL
                     IAVGGITVLLSLFSFLCTFILGLLFCNINISVTLVVKSLVQILSVNLYCYVAVLPIIA
                     YFGRKQNAFLTGVGIAFVYGFCGVFVAGRNLTDFYPITAGLGLVGYNNGAGTVYQPLI
                     GAMTLIVILILTTILLVFTPNYDKVMTISKKKGIKHKKYSHK"
     gene            8796..9332
                     /locus_tag="PC494_003055"
     CDS             8796..9332
                     /locus_tag="PC494_003055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rubrerythrin family protein"
                     /protein_id="HDF3913534.1"
                     /translation="MNLKGTKTEKNLMAGFAGESEARNKYTYYASKARKEGYNQIAAI
                     FEETANNEKEHAKLWFKLLHDGMPSTEENLKDAAAGENYEWTDMYAKFAKEAREEGFD
                     KIAYLFEAVGKIEKEHEERYLKLLENLNEGKIFKRDEEVVWQCQNCGHVYVGTEAPEK
                     CPVCDHPKAYFNIKAENY"
     gene            9364..9753
                     /locus_tag="PC494_003056"
     CDS             9364..9753
                     /locus_tag="PC494_003056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HDF3913535.1"
                     /translation="MKFSKQRELILNEILNNPVHPTADYLYENLKKDNPNLSLGTVYR
                     NLAQLTEHGFIRKVSIPGYPDRFDGRIDNHYHIICEVCGEVYDLESEVLNNLQELISE
                     ETDIKITSYNISFKGICNNCKRCSQVG"
     gene            9790..10176
                     /locus_tag="PC494_003057"
     CDS             9790..10176
                     /locus_tag="PC494_003057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="desulfoferrodoxin"
                     /protein_id="HDF3913536.1"
                     /translation="MCSEQKFFICETCGNLVGMIQSGGVPIFCCGKPMKELVPNTTDA
                     AVEKHVPVIEVDGNNVTVKVSSTTHPMTKEHHIAWVYLMTEQGGQRKCLAVDGEPVVK
                     FALNDDDKVISAYAYCNLHGLWKAEL"
     gene            10303..11745
                     /locus_tag="PC494_003058"
     CDS             10303..11745
                     /locus_tag="PC494_003058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HDF3913537.1"
                     /translation="MSIYKCSVCGYIYDESKNDKTWDELSEDWECPVCTKGRSYFGKI
                     STVYYEEDEKIAEDIVEDESKLNTEKEGDLNYLSTYLRRDDEVEKHMDIIHEMAVTGK
                     SIIEPMRTKLPVISWDDILIMGAQLNPLPLNEHDEVNTTTIIGKKAKKPMIIENPVYI
                     SHMSFGALSKELKIALAKGAAQNKTAMCSGEGGILPEEKEASYKYIFEYVPNKYSVTE
                     ENLKNSDAIEIKIGQGTKPGMGGHLPGEKVTEEIAKVRNKPVGQDVISPSCFEEIQSK
                     EDLKKLVDELREVSEGRPIGVKISAGHIEKDMEFIAYAKPDFVTIDGRGGATGASPKL
                     LKDATSIPTIFALYRARKYIDTHGLDIDLVITGGLRISTDFAKAIAMGADAVAIASSA
                     LMAAACQQYRICGSGKCPVGVATQDEELRKRLHIENSANRVANFLNVSLEELKTFART
                     SGHKDIHDLSVDDLYTVNSEISNYTNIQHV"
     gene            12042..12857
                     /locus_tag="PC494_003059"
     CDS             12042..12857
                     /locus_tag="PC494_003059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HDF3913538.1"
                     /translation="MERLKIQVLVDNNTYIDRYFVGEPAVSYYIEIDGNRILFDSGYS
                     DVFISNAEKLNIDLGNLTHVVFSHGHNDHTRGIQFLENRYDLSTIELISHPNCFIPRK
                     HGEKSIGAPFSAEEIKNIFMYNPKDKPFNLSKNCVFLGEIPSINDFEKRAKIGKCKIG
                     DLWEDDYVLDDSAIVCKTDKGIFIITGCSHSGICNIVEYAKKVCRDDRVIGILGGFHL
                     FELNNRLDSTIQYLDKEEIRMLYPCHCVSFKVKAKMNEILNINEVGVGLTISI"
BASE COUNT         4726 a         1588 c         2446 g         4203 t
ORIGIN      
        1 agaatactta atgctactat atctaaagag ccaagtggta gatattatgt atcattatgc
       61 tgtactgatg tagatattga agcatttgaa aatactaata atcatatagg tttagattta
      121 ggaattaaag aattttgtat ctcaagttgt ggagaattta tagaaaatcc taagtatctt
      181 aagaagtcat taaacaagct tgctaaatta caaagagaat tatcgagaaa aacaatcggt
      241 agtttaaata gaaataaagc aagattagaa gttgcaggac ttcaagaaca tatagctaat
      301 caaagaaagg attttttaca aaaactatct actaaattaa taaaagagaa tgatattatt
      361 tgcatagaag atttacaagt aaagaatatg attagaaatc gtaaactatc tcgcttaatt
      421 tctgatgtgt catggtcaga gtttattcgt caattagaat acaaggctaa ttggcatggt
      481 agacaaattg taaaggtggg taaattcttt gcaagttcac aaatatgcaa taaatgtggg
      541 tataaaaacg aggaagttaa ggatttaaat ataagagaat ggatttgtcc tagttgtaat
      601 gaaactcacg atagagatat aaatgcaagt ataaatatat taaaagaagg attaagacta
      661 ataacaactc aaaataaata acttatgtaa gaaccgtagg aactacgggg atagcctgtg
      721 gagaattagt aagacatatt ttagtatgca aaattctgtg aagcaggaac cctgtgactt
      781 tagtcatggg aggttcagtt tgggcaagta gtttcttgta aatctagtta tgtttcaacc
      841 aatgataata taatttcatt agtattagct ggtaattaag ttaatttgac tagagataag
      901 taaattgatt taaaaggaaa taagtaaatc aacaattaaa tacatctaaa agtaagttta
      961 ttgcaatgaa ttgttaaaga aaataattaa tatggagtaa atctattgca atgaagtaac
     1021 aaagaaaata attaatatag agtaagttta ttgtaatgaa ttgttaaaga aaagagttaa
     1081 tatagagtaa gtttattgta atgaattgtt aaagaaaata attaatatag ggtaaatcta
     1141 tctcaatgaa ataacaaaga aaagagttaa tatagagtga acttattgca atgaatcaac
     1201 aaagaaaata atcaatataa aaaggagaaa tatttatgaa tacaggattt ccaaaagact
     1261 ttttatgggg agcatcatct tctgcatttc aagtggaagg agcttgggat aaagacaata
     1321 aaggaaaaac cgtagccgac tataattctt ttaaaaagtc tcatttacag gcagatacta
     1381 aagtcgcatc agacttttac cataattatg aagaagatat tgaattaatg aaagaattag
     1441 ggatgaaaac atatcgtttt tcaatttcat gggcaagaat aataccagat ggtgaaggag
     1501 agataaacca gaaaggttta gacttttata ataagataat agacaaacta atagagtgtg
     1561 atattgagcc attcgtaact ttataccatt ttgaccttcc atttaaatta gtagagaaat
     1621 ataatggttg ggaaagtaga gaaactgtct atgcttttga aagatttgct aaaatatgct
     1681 ttaagcattt tggagatagg gtaaagtatt ggcaacctca taatgaacag aatttaattg
     1741 ttagagtgga ggagagaatt aatatatatg atgaaacaga ttcatggaag atagataaaa
     1801 tgcgtgctca gatggattat aatctttgct tagcacatgc attagcagtc aatgcatgtc
     1861 atgagatgat aaaagaaagt aaaattggag cagcagtatc atcatctgta acatatcctc
     1921 ttacttctaa gccagaagat gtatatgcag ctagaatgaa tgataatttt aaagtgtact
     1981 atatgcttga tatgcatcat tatggagaat atccagggta ttatatgaag tatcttgaaa
     2041 aaagaaatat agttcctcac atggaagatg gggataaaga gatacttaaa aaagctaaaa
     2101 tggattttat agctgtaaat tattatagga caaattgtgc agaagcttta cctgaagatt
     2161 cacaacatcc atttggatta agagaaggaa ctgttgattt tagtatgtat ggactattta
     2221 aaatgtcaat gaatcctaac ttagaggcct ctgagtatgg agcagcaata gacccatcag
     2281 gtcttagagt tgccttaaat gaatattggc aaagatatca cttacctgtt ataataacag
     2341 aaaatggtct aggagctaaa gatatattag aagatggaaa aattcatgat gactatcgta
     2401 tagactattt aagaagtcat ataaatgcat gtaaactagc tattgaagat ggtgtagaga
     2461 tgattggata ttgtccatgg tcatttacag accttttaag ttcttctcaa ggttttaata
     2521 agcgttatgg acttgtttat ataaatagaa ctgaccatga agttttagat ttaaaaagaa
     2581 tcaagaaaga tagtttttac tggtataaag aagttataga gaacaatgga atagtaaaat
     2641 aaacataaat atatattgag ggttttagta tgtacattac aaaggtatta aataattcgt
     2701 tgctacttgc aaaggatgat aatgatgaag aaataatatt gatggggaaa ggcattggcc
     2761 ataattataa ggccgggtct gagttaaata aaaaagatat agaaaagatt tttgttcttc
     2821 atgatgaaaa tataaaaaag agcattatac aattggcaac agaaatagat gcagaatatt
     2881 ttggtatagc tcaaatgata attgcatatg gaatagaaaa atataactta aaacttatga
     2941 accatatata tttggcctta actgaccaca ttgcctttgc agtgagacgt tttaaagaag
     3001 gtataatgat tgaaaatcac tatttgttcg aaatcaagga atttaatcca aaagagtatg
     3061 atataggaaa atatgctatt actgttttta aggaggttct tggtttagac ctaccagaag
     3121 aagagattgg taatatagca ggccatttta taaatgcaca acaagataat ccttatagtg
     3181 atagaaataa gagaagtgct aaaattgtaa atgctatttt gcaaatagtt cattatcact
     3241 tttctattgt atataataaa gagtcatttt attataggag atttgtaatg catctaaagg
     3301 ccttttcaca aagatttctg gctaatgaac catcaagaga aaaaatagat tttatatatg
     3361 agcaagttca aaaaaattgt aaggaagagt atgaatgtgt gaaaaaggta ggagcttata
     3421 tgtataagga atactccaga gaattaccaa gacaagagga gttatatttg atgattcata
     3481 ttcataagat tttaggagaa ttatgcgaaa atagttagaa tatcttaata tgctagtaat
     3541 attataaaaa attaaaaatt aactacactt taaatatgaa taattgcatt acttaagggg
     3601 gttgtcttaa aattgatttt tttaattaaa tttgaagctc aactcctttt ttaaaccttt
     3661 atatcattac aactttaatg tttatacgcc tgtacttcag atgtatatct actttttaca
     3721 tttctcaaca tgcaaatcta ccattttttg cagtatgtta attgaaataa accattgagt
     3781 taaccctaaa tttattctgg acttatagga atagttccaa agatacttta aaatattttc
     3841 tggaataatt gcttatttca catatgtttt attgtgatgt tttgatttaa taaattcttc
     3901 aactctgtat atagtaaatg tattatcatg tttgttttat tcaagcacac ttataatacg
     3961 cttgattttt tcacaatgat gaaatatact aatgggtgtt ataagtataa gaatagcatt
     4021 acacttgaag aagcaagtga taaatgaggt ataaatcctc atatgataaa ctactatttc
     4081 attgaggagc atattctaaa tgatgtaaag atactacaat atgactaaat tcctaatgat
     4141 aaaaaagtct acgaatgagt gtagaaaggg gaactaagat gaataaagtt ttaattatag
     4201 atgatgataa agatctttgt attttgttaa aaaagagtat ctcaattgaa cagattgaag
     4261 caaactattg ccattctggg agagatggac tggctgaact ttcaaaacaa gattatcagt
     4321 tagtagttct agacgtgatg atgccaggta tggatggttt tgaaactatg gaacaaatac
     4381 gaaaatatag cagtattccc atcttaatgc tgacatcaaa aagcgataat tacagcaaag
     4441 tgcatggatt gcgagctggt gcagatgact atctaaccaa accatttgaa attacagaat
     4501 ttactgctcg tgtactgtct ttaatccgac gttacacccg ttttaatcca aaaaatgagg
     4561 agccacagca actttctttc aaaggtttgt tgattgacct tgaccagcat acagtgacta
     4621 ccaatggcga acctatgttg cttccaccca aggaatttgg tgtgcttctt tactgtgcaa
     4681 agcatcaggg taagattttg acaaaacagc agatttatga agccgtgtgg ggtgagccat
     4741 atgtatatga tgacagcaat atcatggcta ttatcagtcg cctaagaaaa aaaattgaac
     4801 tagacccatc atctcccatc tatttgcaaa caataaaagg aattgggtat caattcaaca
     4861 cggaggtatg aaaatggacg aacaaacgat aattcttttc ttactcttgc tgtcgattgg
     4921 tctacttttt ctttccatat ttgctttttc caagcttggg catatttaca agcgcctaaa
     4981 agatatagag gagatactgg ctgatgtaca aattggagac gaaaatcgta aaatactaat
     5041 taagccatgt gatgttatgg ctccattggt ttatcagctt aatgagattg tctacgatta
     5101 tgaaaataag ttactttctc tgaaaaagtc ggataaagct agcaaacaac ttatgacaag
     5161 tttatctcat gatgttcgta caccattaac aactctgatt ggttatctgg atgctgtaca
     5221 cagtggtata gttatcgaac aagaacgaga ggaatacctt gaaatcgcta ggcgtagagc
     5281 ctacgacctc aaggattaca ttgatgttct ttttgactgg tttcggttga actctgatga
     5341 atttacgctg tcaatagaat ctgtagaaat tgcagagttg tcacgcaata ttttgaaaga
     5401 ctggattcct atattccatg aaaagaaact gaattttgaa attgatattc cagaaaatcg
     5461 actaatggta aacctcgacc cagatggata ttcccgtgtg gtcaataatc tggttcaaaa
     5521 tgttcttgct cacagtaagg ctcggcaaat caagattacc atgagtgagg attccagaat
     5581 ggtattactc cgtgttgagg atgatggtgt tgggattgcc agagaaaatt taccacatat
     5641 ttttgagcga ctgtataagt gtgataaagg acgttcagaa aaaggaagtg gtcttggtct
     5701 atctattgtc agtcaaatgg tggagcgaat gggtggtcag atttccgtag aaagtgagat
     5761 tggaaagtat accatattta cagtgagctt accattaata taaaattgtt tttcccccat
     5821 gtgacatgta tacacagggg gattttttgt aagttataaa gttgcaaggt taatacaagg
     5881 ttgttgcaag gttaatgtaa gattgaggtg gtatgataac tttaataaac aaaggaggct
     5941 tttattattt atgaataatt taattattga aacaaaaaat ctcactaagc aatatggtgc
     6001 tcaaaagagc gtttctaatt tgaatattca cgttcagaaa ggtcgcattt acggattgct
     6061 aggaagaaac ggtgcgggta agacgacaac tatgaaaatg ttattgggtc taacaaaacc
     6121 aactactgga gaaattaaaa tatttggtca ggacattcac aataacgaga agaagcttct
     6181 tcctcgaatt ggatgtttga ttgaatcacc agggttttat cctaatctga caggaacaga
     6241 aaatctcaaa atctttgcaa ggcttagagg aataccaaaa aaaaatgcag tagaatcagc
     6301 actggatgta gtcggtttgc caaacaatga caaaaagtta ttttctcaat actctcttgg
     6361 tatgaaacag aggttggcga ttgctcttgc cattatgcat gacccacaac tgttgatttt
     6421 ggacgagcct atcaatgggc ttgatcctat tggtattgca gaagtaagaa catttattcg
     6481 tgatctctgc acagagcgag gtaaaactat tttgatttct agtcacattc tttctgaaat
     6541 tgccttgttg gcagatgaca ttggcattat tgaccatggt attttgttgg aggaagaaag
     6601 tcttgcccaa ttagaagaaa aaaacagtaa atacatacat tttgctgtat ctgatgcagc
     6661 acaggcagca aggcttctgg aaacccaact taacctgaaa aatttcaaag tagcagataa
     6721 ttacaatatt atgctatatg atacagatgt ttctgttgca gaaataaatc gtgctttcat
     6781 tctaaacaac attgaggtat cagaatctca tttatgcgaa gatactcttg aagattactt
     6841 caagaaagta acagggggtg aaggaattgc ttgatataat ttcatgtgaa ttttcaaaac
     6901 tcaagcggtt aaaatttata ctgatttcta ttttaggtgc ttgcttattt ccaattcccg
     6961 caacaatttt gattgcaaag gataacttgc cctttgagca attgttcaaa ttagttgtca
     7021 attttggata ttttttgcta ttaccaattg tattaagtat tgttgctagc caactatttt
     7081 ttatagaaag agataatgat gtattaaaaa atcttgcaac agtgccagtg caaaaaggaa
     7141 aactggctct ggcaaaattg gctgtgttgc tgtttatatc attgttctac tctgttgcag
     7201 ggttaggagc tactatcatt ggaggtttca ttgttggaat agtagagggg gttgctgtaa
     7261 aattaggaat gagcattgct tttggaatta tgttttttgt tactgtactt cctgttgtgg
     7321 tactcattgt atatttcaat cgcagctata ttttttctat tatactttct tttgtatatg
     7381 ctattttcaa ttttagtata tccttaaata ttatcaattt tgaaccaaat aacccaatat
     7441 taagtgtatt acctgctcct gttataatgc gttggtggat ggcattttgg ggagatccca
     7501 ctggcgaata cacggcactt agacagccat atttgctctc aactcctgct tgtgtaggta
     7561 ttttatgttt gataaccatt atagcagtcc tgctgatttg tatgatatac aaaaagcagg
     7621 agaattagga ggtatctatg cttgatataa ttactacaga atttcaaaaa ataaaaagat
     7681 ataatattct atggattggt gttgttgctg ttctgttttc agcactattg gcagtttttc
     7741 aggttgtaag ttcacacggc agtgaccctc taacgtatga gagctttgca aacggagtta
     7801 tctggaataa tttcagtctt agttttccat ttgggattac acttattgga ggatatctta
     7861 ttaaccgtga atatacagac caaaccttaa aaaacatcct aactgttcct atttcattac
     7921 gcaaattgct agtgggaaaa ttaattgcgg ttggaggaat tactgtattg ttaagtcttt
     7981 tcagcttctt atgcacattt attttggggt tgttattttg caatattaat atatctgtta
     8041 cactcgttgt aaaatcctta gttcagattt tgtctgttaa tctgtactgt tatgttgctg
     8101 ttttgccgat tattgcttat tttggtcgta aacaaaatgc atttctgacg ggtgtaggga
     8161 ttgcatttgt atacggtttt tgtggtgtgt ttgttgctgg aagaaatctg acagactttt
     8221 atccaatcac agcaggtctt ggtctagttg gatacaacaa tggtgctggt actgtttatc
     8281 agccacttat tggtgctatg actttgattg taattctaat cttgacaact attctacttg
     8341 tatttacacc taattatgat aaagttatga ccatatctaa gaaaaaaggg ataaagcata
     8401 aaaagtattc tcataaataa cataaatatt gtttctatta tttaagttgc tagacagtga
     8461 aaagaaaaaa tctgtcgtac agtggctata tgctcatgta ttcaagaagc tacagttttg
     8521 atttttcata actgtagctt ctttttgtat ttattaaatc acgactatca taatacttgc
     8581 aataggtata gcgacaagag agagtactgt catatgtgtt ttatatatta cattaagtat
     8641 attctaaaat atatgtttta aataatatat ttgaaaatag gaatatttaa ataaaaaaaa
     8701 taatattata tatagttgac aaaaattggc aaatgatata atatataaat atagaaatag
     8761 taatcattac tattattaaa agggaggaat taattatgaa cttaaaagga actaaaacag
     8821 aaaagaattt aatggcagga tttgcaggag agtcagaagc aagaaataaa tatacatact
     8881 acgcttcaaa agcaagaaaa gaaggttata atcaaatagc tgctatattt gaagaaactg
     8941 ctaacaatga aaaggaacat gctaaattat ggtttaaact tttacatgat ggtatgcctt
     9001 caacagagga aaatttaaag gatgcagcag caggtgaaaa ctatgaatgg actgatatgt
     9061 atgcaaaatt tgctaaagaa gctagagaag aaggatttga caagatagct tatttatttg
     9121 aagctgttgg aaaaatagag aaagagcatg aagaaagata cttaaagctt ttagaaaact
     9181 taaatgaagg aaaaatattt aaaagagatg aagaagttgt ttggcaatgt caaaactgtg
     9241 gtcatgtgta tgtaggtact gaagcaccag aaaaatgccc agtatgtgac catccaaaag
     9301 catattttaa tataaaagct gaaaattatt aaaaattatc attattaaaa aggaatgtta
     9361 actatgaaat tttctaaaca acgagaactg attttaaatg aaatattaaa taatccggtt
     9421 catcctactg cggattacct atatgaaaac ttaaaaaaag ataatccaaa tttaagctta
     9481 ggaactgtgt atagaaattt agctcagcta acggaacatg gctttataag aaaggttagt
     9541 attccaggat atccagatag atttgatggt cgaatagata atcactatca tatcatatgt
     9601 gaagtatgtg gagaggtata cgatttagaa tccgaagttc ttaataattt acaagaatta
     9661 atatctgagg agacagacat aaaaataaca tcttataaca taagttttaa agggatttgt
     9721 aataattgta aaaggtgtag ccaagtaggt tagttttcaa attctaaaaa taattaatga
     9781 ggtgagttta tgtgtagtga acaaaaattt tttatatgtg agacttgtgg aaaccttgta
     9841 ggaatgatac aaagtggtgg tgtacctatt ttctgttgtg gaaaacctat gaaggaactt
     9901 gttcctaata caacagatgc agcagttgaa aaacatgtac ctgtaattga agtggatgga
     9961 aataatgtta ctgttaaagt aagtagcaca actcatccaa tgactaaaga acatcatata
    10021 gcatgggtgt atcttatgac tgaacaaggt ggtcaacgca aatgtctagc agtagatgga
    10081 gaacctgtag ttaaatttgc tttgaatgat gatgataaag tgatttctgc ctatgcttac
    10141 tgtaatttac atggattatg gaaggctgaa ctgtaatatt taaataaatt gagtcaaaaa
    10201 ggaggctata aatgtatttt catacaaata gcctcctata aatttatata aattcaagtt
    10261 ttaattttgt ttaatgtcaa tataatataa ggagaaaata atatgtcaat ttataaatgt
    10321 agtgtttgtg gatatattta tgatgaatct aagaatgata aaacatggga tgaattaagt
    10381 gaagattggg aatgccctgt atgtacaaaa ggtcgtagtt attttggaaa gataagtact
    10441 gtttactatg aagaagatga aaagatagca gaagacatag ttgaagatga atctaaatta
    10501 aatactgaaa aagagggaga tttaaattac ttaagtacat atttaagaag agatgatgaa
    10561 gttgagaaac atatggatat aattcacgaa atggctgtta caggaaaatc tataatagaa
    10621 cctatgagaa ctaaactacc agtaatttct tgggatgata ttttaattat gggtgctcaa
    10681 ttaaatccat tacctttaaa tgagcatgat gaagtaaata caacaacaat aataggaaaa
    10741 aaagcaaaga aacctatgat tatagaaaat ccagtttata tttcccacat gtcatttgga
    10801 gctttgtcta aagaactaaa aatagcttta gcaaagggtg cagcccaaaa taagacagct
    10861 atgtgtagtg gtgaaggagg tatattacca gaagagaagg aagcttcata caagtatatt
    10921 tttgagtatg taccaaataa atatagtgta actgaagaaa atcttaaaaa ttctgatgct
    10981 atagagataa aaattggtca aggaacaaaa cctggtatgg gaggtcatct tcctggcgaa
    11041 aaagtaactg aagaaatagc aaaagtaaga aataagcctg taggtcaaga tgtaataagt
    11101 ccatcttgtt ttgaggaaat acaatccaaa gaggatttaa agaaacttgt agatgaactt
    11161 agagaagttt cagaagggcg tccaataggt gttaaaattt cagcaggtca tattgaaaaa
    11221 gatatggaat ttatagctta tgctaaacct gattttgtaa ctattgatgg tcgtggtgga
    11281 gctactggag caagtccaaa gttgcttaaa gatgcaactt caattccaac aatatttgct
    11341 ctttatcgtg ctagaaaata catagataca catggattag atatagattt ggttataaca
    11401 ggtgggcttc gtatatctac tgattttgct aaggcaattg ctatgggggc tgatgcagtt
    11461 gctattgcaa gttctgctct tatggcagcg gcgtgtcaac aatatcgtat atgtggttct
    11521 ggtaagtgtc ctgtaggagt agctactcag gatgaggaat tgagaaaaag attacatata
    11581 gaaaacagtg ctaatagagt ggcaaacttt ttaaatgtaa gtttagaaga acttaagact
    11641 tttgctagaa cttctggtca taaagatata catgatttaa gtgttgatga tttatatact
    11701 gttaactctg aaatatcaaa ttatacaaac atacagcatg tatagattga agtttgaaac
    11761 tattagattt tagatagcta taaaagtaaa tgataaatat attttataaa agagagtgtc
    11821 ttaaaatgaa ctttttagtt cataagtcac tctttttttt atgaagccaa atatatttat
    11881 cattttagca atgaaaaaga atcttatctc tttattttga gatagattcc ttctatttat
    11941 gaaaattaaa gatattaaat tgtaaaatat tctgtgatgt cgtactatta aactaaagat
    12001 tctgtacttt aaagtaaata aaaatttaag gagtgattat tatggaaaga ttgaagatac
    12061 aagttttagt cgacaataat acttatattg atagatactt tgttggagaa ccagcagtaa
    12121 gctattatat tgagattgat ggaaatagga ttttgtttga ctcagggtat tcagatgtat
    12181 tcatatcaaa cgctgaaaaa ttaaatatag atttaggaaa tttaactcat gttgtttttt
    12241 ctcatgggca taatgaccat acaagaggta tccagttttt agaaaatagg tatgatttat
    12301 ctacaattga acttatttca catcctaact gttttatacc tagaaaacat ggagagaaaa
    12361 gcataggagc tccattttct gctgaggaaa ttaaaaatat ttttatgtat aatcctaagg
    12421 ataagccatt taatctaagc aagaattgtg tgtttttagg tgaaatacct tctataaatg
    12481 attttgaaaa aagagctaaa attggtaaat gtaaaatagg agatttgtgg gaagatgatt
    12541 atgttttaga tgattctgct atagtttgta aaactgataa aggtattttt attattacag
    12601 gatgttctca tagtggaatt tgtaatatag tagagtatgc taaaaaggta tgtagagatg
    12661 atagagttat tggtatacta ggtggttttc atctttttga attgaataat aggttagata
    12721 gtacaataca atatttggat aaagaagaaa taagaatgtt gtacccttgt cactgtgttt
    12781 cttttaaggt aaaagcgaag atgaatgaaa tattgaatat aaatgaagtt ggagtagggc
    12841 tgaccataag tatatagtat ttgaaagtat ataagattta agttgaaggt taaaaagata
    12901 ttttctatag aaaatatctt ttttgttacg tttattttaa gagaaatcaa tatactttta
    12961 tat
//
LOCUS       DAMKNB010000093        12862 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.099, whole genome shotgun sequence.
ACCESSION   DAMKNB010000093 DAMKNB010000000
VERSION     DAMKNB010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 12862)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12862)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12862
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.099"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            126..314
                     /locus_tag="PC494_003060"
     CDS             126..314
                     /locus_tag="PC494_003060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HDF3913539.1"
                     /translation="MAKVCSVCGKGKVSGNQVSHSNKHNKRTWSANLRSVRAIIDGAP
                     KRVKVCTRCLRSGKIERA"
     gene            complement(474..626)
                     /locus_tag="PC494_003061"
     CDS             complement(474..626)
                     /locus_tag="PC494_003061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoglutarate translocator"
                     /protein_id="HDF3913540.1"
                     /translation="MRNNKSKVLLGILCLATGMAVILSMLLPGWIWSALTALILIGCG
                     ALLFFC"
     gene            complement(724..1200)
                     /locus_tag="PC494_003062"
     CDS             complement(724..1200)
                     /locus_tag="PC494_003062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rpn family recombination-promoting
                     nuclease/putative transposase"
                     /protein_id="HDF3913541.1"
                     /translation="MNLKRSNEKREEYRRMYSDKESFLSLIQNFTSVSIAKELTLKNI
                     ELETSFICEYKGKEVDIIYKVFSKSGKVSHYIVLEFQTEMDTEIVPRLKSYREQIWKS
                     FIMKKSLEEIEDKNFKLPKVIPVVLYSGPERLSRKKGILDIVESISEFSNNSSMKN"
     gene            1419..2180
                     /locus_tag="PC494_003063"
     CDS             1419..2180
                     /locus_tag="PC494_003063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HDF3913542.1"
                     /translation="MEYTVQKLSKLAGISTRTLRYYDEIGLLKPLKINSSGYRIYGQN
                     EVNKLQQILFYRELGINLENIKNIINSPNFDSLSALKEHHNKLLAKRKQIDLLIENVT
                     KTIALKEGKYTMTDIEKFEGFKEKMIDENEKNYGTEIREKYGKDIIDTSNKKLKNMSK
                     QDYENWQNLNIEIISKLKKAFKTGDASSELAQEVAKLHHKWLCYTWNTYSKEAHSSLA
                     QMYVYDERFTSYYDREQPGLAKFLRDAIVIYTRDK"
     gene            complement(2440..4368)
                     /locus_tag="PC494_003064"
     CDS             complement(2440..4368)
                     /locus_tag="PC494_003064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HDF3913543.1"
                     /translation="MHKRLLTLFKLLNESDDKITCKTLSNHLKVSERTIRNDITSING
                     TLEKNGAIIKIKKGEGYYIDILNLALYQQYLALISDDIMDSSEIPDSPIERNQYILKY
                     ILYNNTYIKLEDLANSLYVSKFTILNDIKRIKPILSKYNLILVSKPYYGVKVEGKEID
                     IRRCISNNMINRNFENYIIGITDREIELFNNVDLIELQRVVLSEINKFNINFLDFNLK
                     NFIIHLAITVSRILDGYCLDNVLDVVLTDFQSNTTVENIFNYIESKYTIIISKADRVY
                     LYNHFITKSSLLDNVSNRVDTKIIEYVEEILEVINNQYTFDLRNDSVLFDDLVLHFKS
                     ILNSKSYNLNKVNPLINTIKSNYPLAFEITLNAIEKVFKNSIYSLTEDEIGYVSLHIG
                     AGIERFFQSNIKCKNVVLVCGSGYGSSRLLEVQLNKVFHDKINILQCLSFNQFLASEL
                     SDVDIIISTIPLNHDSIPIVLVDLKLLKKDIENISKSITNNSHIYSNLLDNFFDKNLF
                     IVNPKIKDKDELIKLMCNKLTQSEIVFPSFAESVFYRESLSSTNIDDFLAIPHPMELS
                     SIRTKICISILNEPIYWSENSTVKLIMMLAINKDDYIKINSIYDILLKIIHDNDIRDS
                     ISNCNDFDNFLSIIKSIV"
     gene            4602..5054
                     /locus_tag="PC494_003065"
     CDS             4602..5054
                     /locus_tag="PC494_003065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDF3913544.1"
                     /translation="MVLQEKYIFIDKDLKSKEEVLNFIADSAYILGITTNKEALLKDL
                     LKRENEFPTGIKDGFAIPHTKSVNVKEASILYIKTTNELEWKTLDDSKVRYVFSLLAP
                     HKNEGNIHLKTLSKLATCLMEDDFTSEVKNASDASHLVKYITNKMKEE"
     gene            5057..5365
                     /locus_tag="PC494_003066"
     CDS             5057..5365
                     /locus_tag="PC494_003066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HDF3913545.1"
                     /translation="MKIVAITSCIAGLAHTPMAAKALEQAASKMGHEIKVEQQGAMGR
                     VNTITKEEAQDADFILIASDQTISGMERFDGKKVIKVKIGIALKKPEAVLTKCIEAIS
                     "
     gene            5479..6585
                     /locus_tag="PC494_003067"
     CDS             5479..6585
                     /locus_tag="PC494_003067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HDF3913546.1"
                     /translation="MSKKNKSLLSELKGHLMTGISYMLPLVIGSSLVVAIPKLTALAV
                     GITSLDAYKNVSGFYHILYLMEQVGWTGIGLLNTVLAGFIAFSIGEKPAMGAGFIGGL
                     IASNTNAGFLGAVIAGFFAGYVCKFLKKKIKISGSASGMMPLIIMPLITVGLTGFLMS
                     VVLAGPLGNINTSLNAWVAEMCQNGTNSVVLALILGAMIGFDLGGPVNKAAWMAGNAL
                     LLEGIYLPAILVNCAIVIPPLGYGLATFIRKSKFSNALAETGKGNIVMGIIGITEGAI
                     PFTLTNPLKLVPVNMIGCALGVGLSALLGVHAIMPPVGGLYGFISIGSGWAYLVGAIF
                     GALVIAILSTTLVDFNEDETTENTEFDEIELDIM"
     gene            6660..9338
                     /gene="mngB"
                     /locus_tag="PC494_003068"
     CDS             6660..9338
                     /gene="mngB"
                     /locus_tag="PC494_003068"
                     /EC_number="3.2.1.170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannosylglycerate hydrolase"
                     /protein_id="HDF3913547.1"
                     /translation="MKKTKVHVVPHSHWDREWYFTTSRSKIYLMKDFQDILDILEEKE
                     DFKYFTMDAQASLLDDYLKWRPQDKYRIRDLVQRRRLVIGPWYTQTDQLVISGESIIR
                     NLYYGIDRCNEFGEPMRVGYVPDSFGQSAQMPQIYRGFGIDSSLFWRGVSDDMVDTTE
                     FIWKGSDGSKVLAVQIPFGYYYGGNIPEDDSDLKEYLKDIIVKLKVKASTNNVYFPNG
                     FDQAPIRKNLPDILKKANEIDNENEYEISDIENYIDSVRNERNEFTELKGEFLNAKHM
                     RIHKSIFSSRSDLKIMNNKLENYITNVLEPLLTLSYSLGNEYPHLVIKDIWKLMFENA
                     AHDSIGSCNSDTTNEDVYTRYKQARDLSINLLDLHMRLISTQIKNNNEEITLTVFNGF
                     PEVRNEVVEFDTYIPGQDFVIKNKNGKILNYIIKEKEDITNYILTQTIRLNPSKKIYI
                     PKTVYRAKIALSVKDIPPMGYTQLVFELDTKNKCEIETSNCKEIENKYYKITANKNGS
                     LEILDKESNKTYKNQAVIEDNGDDGDSYNYSPPRKDIYVSSLDSVSSVEVLKSNIQEE
                     MILKYSLTIPASLEERAIGKVSVKMPVTMKITLEPKEQIIKFNVNIKNNQALSHRVRV
                     LFNTEIASKFSIADQQFGIIQRPTVLEKDLALWKRDNYSWQEKPITIEPMQSFVTLED
                     GQRGIALITGCVREYQIVGDNLDTIALTLFRSFGYMGRENLLYRPGRASGEKIIATPD
                     AQLLKELNFDFGLYIYNNKFDEANVANTAKRFLTPIQIYEYADFLNGRLIFAFNDEKQ
                     IYENEFSLMNVNNSNFTVSAIKKEEKGDGIVVRIFNGMKNEDAKGSLNINKNVNDAYS
                     AMLDEIYDNTSKLKVNTKTVEVNSLSHCKVQTIVIK"
     gene            complement(9655..11988)
                     /locus_tag="PC494_003069"
     CDS             complement(9655..11988)
                     /locus_tag="PC494_003069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HDF3913548.1"
                     /translation="MDTKLKKFKDKYIVTIIVFILMLSASLGMISQYSTIQASAKGGA
                     ENPFEQESFVDSIYKGSYVLYHNMKEEQEGKMIQPSKLFINEETMNYIKNVSKEKDTY
                     DGSETYYTDDSINADFNENFENWEHFIKASGKNLKYYLVDKESNFEFFNDNKELGVLD
                     TTKNDASKENSDENQSKNTEMNDEERQKQITDIKENYRFYVVMNFDKDGKVNIVDSYG
                     VNQKIINQMLLSKAREDLMDTSLGGNSISYKLSPIKNITLVYAVPKVISKGDSVEYGY
                     GNTYFDDGIISYISNVENNSYYKISGMILKIILAIVVIVALAFPYRKSKELLGFDTLS
                     RIPLEILFIALDIIQGLVDLYPTVIISNTLSGNYVEYLINNDISAKMASILVSLMNLT
                     YWFVIFSIIFVFIILLKHILNVGIREYFTKHTVTGMFFVWLKKAGKTVINQIRTINLK
                     EKPNKTIVTILGINLLIIVIMCSMWFFGIILALIYSVVLFKILSDYSKKTIYEYNQLL
                     DVTKKISDGNLDVNMEKDLGFFNPIKDELGNIQTGFKKAVDEEVKSQKMKTELISNVS
                     HDLKTPLTSIITYIDLLKDESITDENRKLYIDTLDRKSQRLQHLIEDLFEVSKANSGD
                     VYLNIVNVDIVSLMKQTLLELDDKLADSSLIVKNNFSNEKIILPLDSQRTFRVFENLI
                     INISKYAMPNSRVYIDILETDNKVNIMLKNMSASEIDFSVDDIMERFVRGDKSRNTEG
                     SGLGLAIAKSFIELQGGKMNISVDGDLFKVTITFNKN"
     gene            complement(11963..12679)
                     /locus_tag="PC494_003070"
     CDS             complement(11963..12679)
                     /locus_tag="PC494_003070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF3913549.1"
                     /translation="MNSYNILVVEDEKEIADAIEIYLLNQGYNVFKGYNGLEGLKVIE
                     NQEIHLAIVDIMMPKMDGITLTMKLRENYNFPVIMLSAKSEEVDKIMGLNIGADDYVT
                     KPFKPLELLARVNSQLRRYTKYLNMVGNKEQKVESDDSVFAIGGLELNENTKEVSIDG
                     KYIKTTPIEFKILSLLMRNAGRVFSADEIYERVWNENAVNTDTVMVHVRNIREKIEID
                     PKNPKYLKVVWGVGYKIEKI"
BASE COUNT         4789 a         1793 c         1672 g         4608 t
ORIGIN      
        1 taataagaaa ttcttcaata tgtgtaaggc aaatatatat ttctattgca aatttttgtt
       61 atttatgata atataaatat gtttttagtc tttaaatagt tatcatttta aggaggtgtg
      121 cgtagatggc aaaagtatgt agcgtatgtg gtaaaggtaa ggtttctgga aaccaagtat
      181 cacactcaaa taaacataat aaaagaacat ggtcagctaa cttaagaagc gtaagagcga
      241 ttatagatgg agctcctaag agagtaaaag tttgtactag atgtttacgt tctggtaaaa
      301 ttgaaagagc ttagtaacca cgtttaaaag cctacttccg taagtaggct ttttaattta
      361 atcattttta ctctttctca taaattttag gattatactt gaaatccatt ttggtaattt
      421 tattgttact actttcatca atactcaccc cacactttat agttaaaact attttaacaa
      481 aaaaataata atgctccaca tccaataagt attaatgcgg taagtgctga ccaaatccag
      541 ccaggaagca acattgacag aattacagcc attcctgttg ctagacaaag tattcctagc
      601 aataccttag acttgttatt tctcatggaa cacctccaca tagaacctgt atctataaat
      661 attttcatat tcaagtttat gcgacagttt tccattttag accaataaac acattatgta
      721 attttaattt ttcatactag aattattact gaactccgat atagattcta caatatccaa
      781 aattcctttt tttctactta acctttcagg tccactatat aaaacaactg gtataacttt
      841 aggaagttta aaatttttat cttctatttc ttcaaggctt tttttcataa taaaactttt
      901 ccaaatttgt tctctatacg atttcaatct tgggacaatt tcagtatcca tttctgtttg
      961 aaattctaac actatataat gtgatacttt gccgctttta gaaaatacct tataaattat
     1021 atcaacttct tttcctttat attcacatat aaaagatgtt tctaactcta tatttttaag
     1081 agttaattct tttgctattg agacacttgt aaaattttga atcaaactta aaaaactttc
     1141 tttatctgaa tacattcttc tgtactcttc tcgtttttca ttgcttcttt ttaaattcat
     1201 acagttcctc ctagactata gaccttctat tttttagtaa agatagtcta taaattttat
     1261 tttttaattt tcactagtga gtattgacag ttgtgtgtaa aatatccagt aaagatattt
     1321 ttttatattt ttattaaaag atataaattt ttatatttta atgtattgac atttacgttg
     1381 cgtaaaagtg tatatttaat ttataggagg tactacttat ggaatataca gttcaaaaat
     1441 taagtaaact agctggtata agtactagaa cacttagata ttatgatgaa ataggtcttc
     1501 ttaagccact taaaataaat tcttcaggtt atcgtatata tggtcaaaat gaagttaata
     1561 aacttcaaca aatacttttt tatagagaat taggaattaa cttagaaaat ataaaaaaca
     1621 ttataaattc accaaacttc gatagtttaa gtgcgttaaa agaacaccat aataaattac
     1681 tagccaaaag aaagcaaatt gatttactaa tagaaaatgt aactaaaact atagctctga
     1741 aggagggaaa atacactatg acagatatag aaaaatttga aggttttaaa gaaaagatga
     1801 ttgatgaaaa tgaaaaaaat tatggaactg aaattagaga gaaatatggt aaagatatta
     1861 tagatacatc aaataaaaaa cttaaaaata tgtctaagca agattatgaa aattggcaaa
     1921 acctaaatat cgaaataatt agtaaactta aaaaagcttt taaaactggt gatgcctcta
     1981 gtgaactggc tcaggaagtt gcaaaattac atcataaatg gttgtgttac acttggaaca
     2041 catactctaa agaagctcat tcctctctag cacagatgta tgtatatgat gaacgtttta
     2101 catcatatta tgatagagaa caacctggat tagctaagtt tttaagggat gctatagtaa
     2161 tatatacaag agataaataa tataaaataa taaaggtggt gtctcaaaat gaacttttta
     2221 gttcatgaga cactcttttt tgtatgaaat cagatatatt tttatcattt tatcaatgaa
     2281 aaacaggttt ctctctctat tttgagacag aatctttatt gtataataat tataatcaat
     2341 acaaaataat aacaaattat acaaaactta cttatactat ttatgctaaa aacaaaaaat
     2401 attttattaa agtttttaaa acttatgtaa tataaaaatc tatactatag acttgattat
     2461 ggaaagaaaa ttatcaaaat cattacaatt agatatacta tctctaatat cattgtcatg
     2521 aattatcttt aaaaggatat cataaatgga gtttattttt atataatcat ctttatttat
     2581 agccaacatc atgattaatt taacagtaga attttcactc caatatattg gttcattcaa
     2641 tatggaaata caaatcttag ttcttataga gcttaattcc ataggatgag gtatagctaa
     2701 aaaatcatct atattggtag aagataaact ttctctgtaa aatacagatt cagcaaatga
     2761 tggaaataca atttcacttt gagttaattt gttgcacatc aactttataa gctcatcttt
     2821 atctttgatt ttaggattaa caataaataa atttttatca aagaaattgt ccaaaagatt
     2881 actataaata tgggaattat tagtgattga cttagatata ttctctatat ctttttttaa
     2941 tagttttaaa tccactaata caataggaat actatcatga tttaaaggaa ttgtcgatat
     3001 tattatatct acatctgaca attcactagc taaaaattga ttaaatgata gacattgaag
     3061 tatatttatt ttatcatgaa aaactttgtt taattgaacc tctaataacc tacttgaacc
     3121 ataccctgaa ccacatacta atactacgtt tttacactta atattacttt gaaaaaatct
     3181 ctctattcca gcacctatat gcagggatac atatccaatt tcatcttctg ttaaagagta
     3241 aatactattt ttaaaaactt tttctatagc atttaaagtt atttcaaatg ctaaaggata
     3301 attactcttt attgtattta taaggggatt caccttattt aaattataag atttagaatt
     3361 gagaattgat ttaaagtgca gtactaaatc atcaaataat acactatcat ttctaaggtc
     3421 aaaagtatat tgattgttga ttacttctaa aatttcttca acatactcta taattttagt
     3481 atctacccta ttggaaacgt tatccaaaag agaactttta gttataaaat gattatatag
     3541 ataaactctg tctgcctttg aaataattat agtatattta ctctcaatat aattaaatat
     3601 attttcaaca gttgtattcg attgaaaatc tgttaaaaca acatctaaaa cattatctaa
     3661 gcagtaacca tcaagtattc tacttacagt aatagctaaa tggataataa agttttttag
     3721 attaaaatct aggaaattga tattaaattt attaatttca cttaacacta ccctttgaag
     3781 ctctattaaa tctacattat taaataattc tatttctcta tctgtaattc caattatata
     3841 gttttcaaaa ttcctattta tcatattatt agaaatacat cttcgaatat ctatttcctt
     3901 accttcaact ttaactccat aatatggctt agaaactaat attaaattat actttgacaa
     3961 aataggcttt attcttttta tgtcatttag tattgtaaat ttactcacat acaagctatt
     4021 agctaaatct tctagtttta tatatgtatt gttatagaga atatatttta aaatatattg
     4081 atttctttct ataggagaat ctggtatttc acttgaatcc ataatatcat cagatattaa
     4141 tgctagatac tgttggtata atgctaaatt aagaatatct atataatatc cttctccttt
     4201 ttttatttta ataatagcac catttttctc taaagttcca tttatagaag taatatcatt
     4261 tcttatagtt ctctcactca cttttaaatg attacttaaa gttttacaag taattttatc
     4321 atcactttca tttaataatt taaacaacgt gagcaatctc ttgtgcataa atatcccccc
     4381 ttatagaatt tcttctaaat tatactattt acactcatat aatacaatta ctctaataaa
     4441 attgtattat aataatttat ttccacttct atatggaaat tagttattat cataatataa
     4501 atttccatgt cgaagtggaa attagttata tttaatttaa ttaggataat gattacaata
     4561 taaatataag ttaagacatt atgaatggag tggaaaaata tatggtacta caagaaaaat
     4621 atatatttat agataaagac ttaaaaagca aagaagaagt attaaatttt attgcagata
     4681 gtgcttatat actaggtatt acaactaata aagaggctct tttaaaagac cttctaaaaa
     4741 gagaaaatga atttccaaca ggaataaaag atggatttgc gatacctcat acaaagagtg
     4801 taaatgtaaa ggaagcttcc atactctata ttaaaacaac taacgagtta gagtggaaaa
     4861 ctttagatga tagtaaggtt agatatgtat ttagtttgtt agccccacat aaaaatgaag
     4921 gaaatataca tttgaaaact ctatctaaat tagccacatg tttaatggag gatgatttta
     4981 caagtgaagt taaaaatgct agtgatgcaa gtcatttagt aaaatatata actaataaaa
     5041 tgaaggagga ataattatga aaatagtagc tataacatca tgtatagcag gattagcaca
     5101 cacacctatg gcagcaaaag ctttagaaca agctgcatca aaaatgggtc atgaaatcaa
     5161 agtagaacaa caaggtgcta tgggacgagt aaatactata acaaaagaag aagcacaaga
     5221 tgcggacttt atacttatag catctgacca aactatatct ggaatggaaa gatttgatgg
     5281 taaaaaagtg ataaaagtca aaataggtat agcgttaaaa aaaccagaag ctgtcttaac
     5341 aaagtgtata gaagctattt cttaataaaa aaatctcact ctaatataga atgagaaaaa
     5401 tcaaaaatta aaaaattgtc taatgtaatt ataacatatt atcaaaaaat ataacaaact
     5461 tatataggag gattaaaaat gagtaaaaaa aataaatctc ttttaagtga acttaaggga
     5521 cacttaatga caggtatctc atatatgttg ccacttgtaa taggctcatc tttagttgta
     5581 gctatcccaa agcttacagc tttagcagtg ggtataacaa gtttagatgc ttataaaaat
     5641 gtatctggtt tttatcatat tctttactta atggaacaag ttggttggac tggcataggt
     5701 ctattaaata cggtattagc aggatttata gcattttcaa taggtgagaa accagctatg
     5761 ggtgcaggtt ttattggtgg gctcatagca agtaatacta atgcaggatt cttaggagca
     5821 gtaatagcag gtttctttgc tgggtatgtt tgtaagtttt taaagaaaaa aattaaaata
     5881 tctgggtcag catcaggaat gatgccactt ataataatgc cacttataac agttggatta
     5941 actggttttt taatgagtgt tgtattagca ggacctttag gaaacataaa tacttcatta
     6001 aatgcttggg tagctgaaat gtgtcaaaat ggaacaaatt cggtggtatt ggctttaatt
     6061 ttaggcgcaa tgataggatt cgatttaggt ggaccagtaa ataaagcagc ttggatggca
     6121 ggaaatgcat tattgttaga gggaatctat ctaccagcga tattggtaaa ctgcgcaata
     6181 gttatacctc cactaggata tggtttagct acattcataa gaaaatcaaa attttccaat
     6241 gcattagctg aaacaggaaa aggcaatata gttatgggta taattggaat aacagaaggt
     6301 gcaattcctt tcactttaac aaatccatta aaattagttc ctgttaatat gataggatgc
     6361 gctttgggtg taggattatc agctttgtta ggtgtacatg ctataatgcc tccagttggt
     6421 ggattatatg gatttatatc aataggttct ggatgggctt acttagtagg tgcaatattt
     6481 ggagctttag taatagcaat attatcaaca actttagtag acttcaatga agatgaaact
     6541 acggaaaata cagaatttga tgaaatagag ttagatataa tgtaaattaa aaacttaatt
     6601 ttagataatt gagaattgag tgtactctca attctcaatt aaattttggg aggattttta
     6661 tgaaaaagac aaaagtacat gtagttccac acagtcattg ggatagagaa tggtatttta
     6721 caacatcaag gtcaaaaata tatttaatga aagattttca agatatatta gacatattgg
     6781 aagaaaaaga agactttaaa tactttacta tggatgcaca agcttctctc ttagatgatt
     6841 atttaaaatg gagacctcag gataaatata gaataagaga tttagttcaa agaagaagat
     6901 tagttattgg accttggtat actcaaacag accaattggt tatatcagga gaatctataa
     6961 ttagaaacct ttactatgga atagatagat gcaatgaatt tggtgaacct atgagggttg
     7021 gatatgtacc agattctttt gggcaatcag ctcaaatgcc acaaatatac agaggttttg
     7081 gaatagatag ttcattattt tggcgtggag tttctgatga tatggtagat acaacagagt
     7141 ttatatggaa aggttctgat ggttcaaaag tattagcagt tcaaatacca tttggttatt
     7201 actatggagg taatatacca gaagatgatt cagatttaaa agaatattta aaagatataa
     7261 tcgtaaaact taaggttaaa gcttctacta ataacgtata ttttccaaat ggatttgacc
     7321 aagcaccaat aagaaaaaac cttcctgata tattaaaaaa agctaatgaa atagataatg
     7381 aaaatgaata cgaaataagt gatatagaaa actatataga ttcagtaaga aatgaaagaa
     7441 atgaatttac agagcttaaa ggtgaatttt taaatgctaa acatatgaga atacacaaat
     7501 ccatattctc ctcaaggtca gaccttaaaa taatgaataa caaattagaa aattatatta
     7561 caaatgtact tgaaccgtta ttaacattaa gttattcact tggaaatgaa taccctcacc
     7621 tagttataaa agatatatgg aaacttatgt ttgaaaatgc agctcatgac agcataggtt
     7681 cttgtaatag tgacacaaca aatgaggatg tatacacaag atacaaacaa gccagagatt
     7741 tgagtataaa tttattagat ttgcatatga gacttataag tactcaaatc aaaaataata
     7801 atgaagaaat aacattaaca gtattcaatg gattcccaga agtcagaaat gaagttgtag
     7861 aatttgatac ttatattcca ggtcaagatt ttgtgataaa gaataaaaat ggaaaaattc
     7921 ttaattatat aataaaagaa aaagaagata ttacaaatta tatattaact caaacaataa
     7981 gattaaaccc aagtaaaaaa atatatatac ccaaaactgt atatagagca aaaattgcac
     8041 tttcagtaaa agatatacca ccaatgggat atactcaact agtttttgaa ttggatacta
     8101 aaaataaatg tgaaatagaa acaagtaatt gcaaggaaat agaaaacaaa tactacaaaa
     8161 taacagccaa taaaaatggt tcattagaaa tattagataa agaatctaat aagacttata
     8221 aaaaccaagc tgtaattgaa gacaatggag atgatggaga ttcatacaac tattctcctc
     8281 caagaaaaga tatttatgtt tcatctttag attctgtatc ttcagtagaa gtgctaaaat
     8341 caaacattca agaagaaatg atacttaaat attcattgac cataccagct tcactggaag
     8401 aaagggctat aggtaaagtt tctgtgaaaa tgccagtaac aatgaaaatc accttagaac
     8461 ctaaagaaca aataattaag tttaatgtta atataaaaaa taaccaagca ctatctcata
     8521 gagtaagagt tttatttaat acagaaatag catctaagtt ttctatagca gatcaacaat
     8581 ttggaataat acaaagacca acagtattag aaaaagacct tgcattgtgg aaaagagaca
     8641 attactcatg gcaagaaaaa cctataacta tcgaaccaat gcaaagtttt gttactttag
     8701 aggatggaca aagaggaata gcattaataa ctggttgtgt aagagaatat caaatagttg
     8761 gtgataattt agatacaata gcattaacac tattcaggtc atttggatat atgggaagag
     8821 aaaatttact ttatagacca ggaagagctt ctggagaaaa aataatagca acaccagatg
     8881 cacaattact taaagagtta aactttgact ttggtcttta catatataac aataaatttg
     8941 atgaagcaaa tgtagctaat acagctaaga gattcttaac acctatacaa atatatgaat
     9001 atgctgattt tttaaatggt agacttatat ttgcattcaa tgacgaaaaa caaatatatg
     9061 aaaatgaatt tagtttgatg aatgtaaata attcaaattt cacagtaagt gcaataaaga
     9121 aagaagaaaa aggagatgga attgtagtta gaatcttcaa tggtatgaaa aatgaggatg
     9181 ctaagggaag tcttaacatc aataaaaatg tcaatgatgc ttatagtgca atgctcgacg
     9241 aaatctatga taatactagc aagcttaaag taaatactaa aactgtagag gtaaattctt
     9301 tatcacattg taaagtacaa acaatagtaa ttaaataata taaaatagct tatacaagat
     9361 ttcaaaataa attgctagta ccatgttaat agtaaagcca gatattatgc tatttataag
     9421 ctctgtaaca ctaaataaca ttttgtaaaa taaaaaggtg aaccttgtat attaggattc
     9481 acctttttta aataaatcaa cattctgttt taaaataaca tttataagct gttttgaaat
     9541 aatgcttaca aattatttta aaacaatacc tataaatttt tatttaaaga atacacataa
     9601 atatttccag actcttttat cctatagact ttataattat taaagaagtc taatctaatt
     9661 tttgttaaaa gtaattgtaa ctttaaataa atcaccatcc acacttatat tcatcttacc
     9721 accctgtaat tctataaaac tttttgctat cgctaaacca agaccagaac cttctgtgtt
     9781 acgtgattta tctcctctta caaatctctc cattatatca tctacactaa aatcaatctc
     9841 agatgcagac atatttttaa gcataatatt tactttatta tctgtttcta aaatatcaat
     9901 atacactctt gaatttggca ttgcatattt gcttatattt attataagat tttcaaatac
     9961 tctaaatgta cgctgactat ctaatggtaa tattattttt tcattagaaa agttattctt
    10021 tactattaga gatgaatctg caagtttgtc atctaattct aaaagtgtct gcttcattag
    10081 agatacaata tccacattta ctatattcaa ataaacatct ccactatttg ccttgcttac
    10141 ttcaaacaaa tcttctatta gatgttgcaa tctttgtgac tttctgtcta atgtatcaat
    10201 atacaactta cgattttcat ctgttatact ttcatctttt aataaatcta tataagtgat
    10261 tatagatgtt agaggtgttt ttaagtcatg tgatacattt gatataagct ctgttttcat
    10321 cttttgactc ttaacctctt cgtcaacagc ttttttaaat ccagtttgaa tatttcctaa
    10381 ttcgtctttt ataggattaa aaaatcctaa atctttttcc atatttacat ctaagtttcc
    10441 atctgaaatt ttctttgtaa catctaaaag ttgattatat tcatatattg tctttttaga
    10501 gtaatctgac agtattttaa ataatactac tgaatatatt aatgcgagta ttattccaaa
    10561 gaaccacata ctacacatta taactataat caataaattt attcccaaaa ttgtaactat
    10621 agttttattt ggcttttctt ttagatttat tgttctaatt tgattaataa ctgtttttcc
    10681 tgcttttttt agccatacaa aaaacattcc tgtcacagta tgttttgtaa aatactctct
    10741 tattccaaca tttaaaatat gttttaaaag tattataaat acaaatatta ttgagaatat
    10801 tacaaaccaa taagttaaat tcattaaact taccaatata ctagccattt tagcacttat
    10861 gtcattgttt ataaggtact ctacataatt cccactcaag gtattactta ttataacagt
    10921 aggatataaa tctacaagcc cctgtataat atcaagagca ataaagagta tctctaacgg
    10981 tattcttgat aatgtatcaa atcctagcaa ctctttagat tttctatatg ggaatgctaa
    11041 agctacaata acaactatag ctaatataat ttttaaaatc attccagaaa tcttataata
    11101 agaattattt tctacattgc ttatatatga aattatacca tcatcaaaat aagtatttcc
    11161 ataaccatac tctacactat cacctttact tattacttta ggtacagcat atactaatgt
    11221 tatatttttt attggagata acttatatga aattgaattt cctcctaaac ttgtatccat
    11281 taaatcttct cttgctttag ataacaacat ttgattaata attttttgat ttactccata
    11341 agaatccaca atatttactt ttccatcttt atcaaaattc attacaacgt agaatctata
    11401 gttttctttt atatctgtaa tctgcttttg tctttcctca tcattcattt ctgtattttt
    11461 tgactgattt tcatcagaat tttcttttga agcatcattt tttgttgtat caagtactcc
    11521 taattcttta ttatcattaa aaaattcaaa attgctttct ttatcaacta aatagtactt
    11581 taaattcttt cctgacgctt taatgaaatg ctcccaattt tcaaagtttt cattaaaatc
    11641 tgcattaata ctatcatctg tatagtaagt ttctgaacca tcataagtat ctttttcttt
    11701 acttacattt tttatatagt tcatagtttc ttcattgata aatagttttg atggttgtat
    11761 catcttacct tcttgttctt ccttcatatt atgatataaa acataacttc ctttatatat
    11821 actatctaca aagctttcct gttcaaatgg attctctgct ccacctttag cacttgcttg
    11881 tatagtagaa tattgactaa tcatacctaa tgatgctgat aacataagta taaaaactat
    11941 aatagtaact atatatttat ctttaaattt tttcaatttt gtatccaaca ccccacacca
    12001 cctttaaata tttaggattt tttgggtcaa tttctatctt ttcccttata ttcctcacat
    12061 gtaccataac tgtatctgta tttacagcat tctcattcca aactctttca tatatttcat
    12121 cagcagaaaa aactcttcct gcatttctca taagtaaact tagtatttta aattctatag
    12181 gagttgtttt tatatacttt ccatcaatac taacttcttt tgtattttca tttaattcta
    12241 atccgcctat tgcaaacaca ctatcgtcac tttctacctt ttgctcttta tttccaacca
    12301 tgtttagata cttagtgtac cttctaagtt gtgaattaac tctagccaat agttctaatg
    12361 gcttaaaagg ttttgttaca taatcgtctg ctcctatatt aagccccatt attttgtcaa
    12421 cttcctctga ttttgcagat agcattatta ctggaaaatt atagttttct ctaagcttca
    12481 ttgtaagtgt tataccatcc attttaggca tcattatatc aactatagct aaatgtattt
    12541 cttggttttc tataacctta agaccttcta atccattgta tcccttaaaa acattatatc
    12601 cttgatttaa tagatatatt tctatagcat ctgctatctc cttttcatct tctaccacca
    12661 aaatattata tgaattcatt ctaatctcct ttatattaat ttataaattt tctttacata
    12721 tatgattata caatatgata gaagtttttc catttatata tatatttata tcttttgttc
    12781 tggttatttg tatttaatgt ccatcttaga aacctccttc tagtttaaat ttaatatttt
    12841 ttcattttgt tttatatact ta
//
LOCUS       DAMKNB010000094        12785 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.100, whole genome shotgun sequence.
ACCESSION   DAMKNB010000094 DAMKNB010000000
VERSION     DAMKNB010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 12785)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12785)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12785
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.100"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            128..1618
                     /locus_tag="PC494_003071"
     CDS             128..1618
                     /locus_tag="PC494_003071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HDF3913550.1"
                     /translation="MFQFETQIHKLRHDVLTAIARLGKEDNLTREAMDNIQYEIIKGE
                     KPTYRCCVYKERAIISERVNVSMGLQPGQDKIDLDTMDIEEDEQIIYILEAACDSCPI
                     NEFTVTDICRGCLAHRCKEACKFGAITHVGGMAYINHELCKACGMCKKACQYDAISEV
                     VRPCKSVCPTNALGFDRENMKAMIHEDKCLNCGACMSACPFGAISDKSLIAPVARKLV
                     QKEKMYAVVAPAITGQVEANVTYGQIKNAIKSLGFVDVLEAACGADAVTVHESLEFAE
                     RMEKGEAFMTNSCCPGFVGYIEKTYPNHVGKISSTVSPMIASGRFIKSHEPDAKVVFI
                     GPCTAKKSEAAKKELKGAVDYVLTFEEIMALFEAFDIDLAKCSNEDIDDASIFGRGFG
                     AAGGLTKAIENYLAEKGIGVNFEPVKISGSREIKKTMTMANLGKLEGNFIEGMMCEGG
                     CINGSGKFLSGAKVKATFDRKNSQSTKKSVLANTKIKDFSNINLEK"
     gene            1898..3394
                     /locus_tag="PC494_003072"
     CDS             1898..3394
                     /locus_tag="PC494_003072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HDF3913551.1"
                     /translation="MFEFETQLKRLKHEVLTAVARLSIEENLTKENIEKIPYEIIKGE
                     KARYRCCVYKEREVVLERAQLALSLTPNSKYGDINPDSVSLDTDEQIIYIVEAACDRC
                     PINEFTVTELCRGCLAHRCKEACKFGAISYINGRAYINHDLCKACGMCKSSCQYDAIS
                     EVVRPCKSVCPTGALDFNRNTMKAMIHEDNCINCGACMSACPFGAISDKSLIAPVAKK
                     LAKKENMYAIVAPAITGQIDSNITYGQLKNAIKSLGFVDMIEASCGADAVTVHESNEL
                     IERIKSGDNYMTNSCCPGFFKYIEKMFPDEKDRISSTVSPMVATGRLVKKIDSDAKVV
                     FIGPCTAKKSEATEKSLKDSVDYVLTFEELMALFEAFNIDLSKCSNEDINDGSIFGRG
                     FGASGGLAKSVQNYIAEKGLSFDFEPIKVSGPRQIKKTMTMAKLGRLEGNFIEGMMCE
                     EGCINGAGKFLSGVKAKNTFDRKNGQSTKKSVLSNDKIKEFEDVNLER"
     gene            3539..4465
                     /locus_tag="PC494_003073"
     CDS             3539..4465
                     /locus_tag="PC494_003073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HDF3913552.1"
                     /translation="MRKIVLKDILFLVTTLSIIVILLLVTNITTNSKIKSTSESYLKS
                     DKNSVRQNGIQRSTKSSTKNTAFKTTILNTGKSDCILVEIGNKVIMIDTGEDKNGKQI
                     VDRLKEKGINTLDYLILTHLDKDHIGGVDSVLSSVKVKNIIQANYKKDSKQYDEYIDS
                     LKKADIEPVLLKDNMNIVINGAEINIHPASKSKYESSNDYSIITNISYGAHKFLFAGD
                     AEEERLSEFINGNTLKYDFVKMPHHGRYDKLTETFLESISPQYAVITCSEKKEPEEGV
                     LKILERLNIKTFLTSNGEVVINSDSKTLSVNQ"
     gene            4583..4774
                     /locus_tag="PC494_003074"
     CDS             4583..4774
                     /locus_tag="PC494_003074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3913553.1"
                     /translation="MLDRFFGEGGFGGCAWWIIILFFLFLAFQDCWAEMDLCAWIPFL
                     ILLLILCECGDVFDGGCGC"
     gene            4997..5347
                     /locus_tag="PC494_003075"
     CDS             4997..5347
                     /locus_tag="PC494_003075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3913554.1"
                     /translation="MAIVDKIFNEIKLMVARLLLGKKYSEYEEKDLVYNTEEEVILIT
                     LKRLVFQGNVNEAEEILFDKAKSVNSENMQYIAIEFYTMLMEKTDEELEAMNFSKQEV
                     YQGIEDIRKVLNLE"
     gene            5609..7114
                     /locus_tag="PC494_003076"
     CDS             5609..7114
                     /locus_tag="PC494_003076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003374392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HDF3913555.1"
                     /translation="MKVGFDHKKYLEEQSKYILERVNNFDKLYLEFGGKLMGDLHAKR
                     VLPGFDENAKIKVLQHMKEKVEVVICVYAGDIERNKIRGDFGITYDMEVLRLIDDLRG
                     YELDVNSVVITRFEGQPATTVFINKLERRGIKVYKHYPTKGYPSDVETIVSDEGYGAN
                     EYIETTKPIVVVTAPGPNSGKLGTCLSQLYHENKRGNVVGYSKFETFPVWNVPVKHPL
                     NIAYEAATVDLKDVNMIDSFHLETYGEMSVNYNRDLELFPVLKKIIEKITGKESIFQS
                     PTDMGVNRVGFGIIDDEVIRKASIEEIIRRYFKTACEYKKGQVDKGAYDRMKMIMEEL
                     NLKPEDRNVVLPARNYSNKLKESADKNDTCPVVALELEDGTILTGKGSDLMNGTAAVV
                     LNAIKHLANISDDMHLISPVILEPIINLKTKTLASRNVSLSCQEVLTALSICAVTNPT
                     AQFAMEKLALLKGCQAHSTTILNRDDEQTFRKLGIDVTCDPEYPSQNLYYS"
     gene            7504..8601
                     /gene="dinB"
                     /locus_tag="PC494_003077"
     CDS             7504..8601
                     /gene="dinB"
                     /locus_tag="PC494_003077"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HDF3913556.1"
                     /translation="MKHYRKIIHIDMDAFYASIEQRDNKKLKGRPVIVGGNPQSRGVV
                     ATCSYEARKFGIHSAMPSAVAYNRCPYAVFVRPRFDVYKSVSEQIRDIFYRYTDLVEP
                     LSLDEAYLDVTKNKKNIDSSIEIAKQIKKDIFREVGLTSSAGVSYNKFLAKIASDLRK
                     PNGLTVITEENAQDFLDKLPVNKFFGVGKVTSNTLKNLGIKTGYDLRCLNLFELENIF
                     KKRGYELYKFARGIDDRPVEPNRVRKSVGAETTLSHNLDIDEEETRNILDELCEEVCH
                     RLKNSEKFGKTLTLKIKYEDFTKITRSLSLEHYIDEYNDIRSGVDNLLRNVEVNGKQI
                     RLLGVTISNLSDKKETYKDITLFEYMDSIQM"
     gene            8871..10007
                     /locus_tag="PC494_003078"
     CDS             8871..10007
                     /locus_tag="PC494_003078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF3913557.1"
                     /translation="MIEIRNVTKKIGNNVILDDISLVVETGTLVVLIGSSGCGKTTTL
                     KLINKLIKPTSGEIYINGKPISQENEIELRRKIGYVIQNTGLFPHLTIKENIELIPRL
                     KKEKSVEEIEKRTLQLLEMVGLDSDEFLNKYPSELSGGQQQRIGVARAIATDAEIILM
                     DEPFSALDPITRTSLQEQLFSLQDELKKTIIFVTHDMDEALKIADKICIMKDGRIAQY
                     DTPENILRKPANDFVKDFIGEDRVWDNPEYIKARDIMIKNPIAVNSTRTVTQGIEIMR
                     TSKVDSLLIIDRAKTLKGIVTVKDMKDIDDKSILLADIMSSEPLHVNEGDNLVEILNV
                     MNRNSVGYIPVISDENKLVGLITRSSLLSVLSEQFLEMEVSVLG"
     gene            10000..11547
                     /locus_tag="PC494_003079"
     CDS             10000..11547
                     /locus_tag="PC494_003079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HDF3913558.1"
                     /translation="MANFFNFILLQKDKIIELLIQHMSLTVTSILIAIIVGVPLGIII
                     SRISSLRKFVLGFVNLVQAVPSMALLGLLVPILGIGSKPAIFMVVVYSLLPIVKNTYI
                     GITSIDPVVLESAKGIGLTRNQTLFKIQFPLALPIIMGGVRISAVTAVGLMTLAAFIG
                     AGGLGYLVFSGVQTVNNNMILAGAIPSCIIALLVDYLFSKIEVAVTPKGLNPKAPKKN
                     YIALKVISVVVVVSMLFVVFSSSFSSKKDTITIGSKDYTEQLILGNVYAELVEKNTNL
                     KVKKNLNLGGSSVAFNAIKSGELDMYVDYTGTLLVNVMKHAPIKDADEAYNVVKDTME
                     KENQLTLLDPLGFNNTYTLAMMPETAEKYGINTISDLTKYGKEFTFSPTLEFENREDG
                     LVGLSRDYGLKFKDVKAMNGSLRYTALDNNESQVIDAFLTDGLIKKFNLKILEDDKNF
                     FVPYYAAPLVREDTLKKYPELEKVMNMLSGKINEETMRELNYQVDELGKSPEEVAHSF
                     LVKEGLV"
     gene            11881..12747
                     /locus_tag="PC494_003080"
     CDS             11881..12747
                     /locus_tag="PC494_003080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HDF3913559.1"
                     /translation="MDNYKKVKQVLWIILFANFAVALLKIIIGNQIKSYSMTADGFHS
                     LSDGASNIVGLIGIFFASKPKDKNHPYGHKKFEIITSLFISGMLFVIAIKIILSAVLR
                     IANPVVPAITIESLIALIITLFINIFVCMYEYRIGTKLNSYVLISDSLHTRSDIFVSL
                     GVLVTLVGVKLGFPVIIESIVPIIISAFIIYSAYGIFRPSIGILVDRVAVDEDYIKEI
                     VFEFNEVRDVHNIRSRGSKSSIYIDMHVMVDPFISVEQSHDLTHKIEKQIQEEINENA
                     QVIVHIEPFYSF"
BASE COUNT         4954 a         1339 c         2332 g         4160 t
ORIGIN      
        1 caaaaaaaca ctatatatat tcgataaaat aaaatttaaa catataatat tttatgtata
       61 tattaataaa aggacatatt gtgttataat ggtatcgtat aaaatcattt acgggggtgg
      121 tattaaaatg tttcaatttg aaacacaaat acacaaatta agacatgatg ttttaactgc
      181 aatagctaga cttggaaaag aagataacct taccagagaa gcaatggata atattcagta
      241 tgaaataata aaaggtgaga aacctacata cagatgctgt gtttataaag aaagagctat
      301 aatatctgag agagtaaatg taagtatggg gttacaacca ggtcaagata agatagattt
      361 agatacaatg gatatagaag aagatgaaca aattatatat attttggaag ctgcatgtga
      421 cagttgtcca ataaatgaat ttacagtaac agatatttgt agaggatgtc tagcacatag
      481 atgtaaagaa gcttgtaaat ttggagctat aacacatgtc ggaggaatgg cctatataaa
      541 tcatgaatta tgtaaggctt gtggaatgtg taaaaaagct tgtcaatatg atgccatctc
      601 agaggttgtt agaccatgta agagtgtttg tccaactaat gccttaggat ttgatagaga
      661 aaatatgaaa gctatgatac atgaggataa atgtttaaac tgtggagcat gtatgtcagc
      721 atgtccattt ggagcaatat ctgataagag tttgatagct cctgtagcta gaaagttagt
      781 tcaaaaagag aaaatgtatg cggtggtagc tccagctata acaggtcaag ttgaagcaaa
      841 tgttacatat ggtcaaataa aaaatgctat aaaatcacta ggatttgttg atgtattaga
      901 agcagcttgt ggagcagatg cagttacagt tcatgaaagc ttagaatttg ctgaaagaat
      961 ggaaaaggga gaagctttta tgacaaattc ttgttgtcca ggatttgttg gttatataga
     1021 aaaaacatac ccaaatcatg tagggaaaat atcttctaca gtatctccta tgatagctag
     1081 tggtagattt ataaaaagtc atgaaccaga tgctaaagtt gtattcatag gaccatgtac
     1141 agccaaaaag agtgaggcag ctaagaaaga attaaaagga gctgttgatt atgtacttac
     1201 ttttgaagaa ataatggcat tatttgaggc atttgatata gacttggcta agtgttcaaa
     1261 tgaagatata gatgatgcat caatttttgg aagaggtttt ggagctgctg gtggtcttac
     1321 aaaagctata gaaaattatc ttgctgaaaa aggtattggt gttaattttg aacctgtaaa
     1381 gatttctggt tcaagagaaa tcaagaaaac tatgactatg gctaatttag gaaagctaga
     1441 aggtaatttt atagaaggaa tgatgtgtga aggtggttgt ataaatggtt ctggtaaatt
     1501 cttatcaggt gcaaaggtta aagccacttt tgatagaaaa aattctcaat caactaagaa
     1561 aagtgtctta gcaaatacaa agataaaaga ttttagtaat ataaatttag aaaaataaag
     1621 ataatacaaa gcaacaaaaa tacatattgt taatagagtt gttctaagtt gaggtttaac
     1681 ttttggacaa ctctattttt atttatatat ttaattattg aacaactaaa ataaaaatta
     1741 tatacactta aaataaaaat tacatatata atattttgta tataacttaa caaagtatat
     1801 gcctatgtta taataattta tagaaataaa taaaaaatac aatatacata atagtagaaa
     1861 tatagcaaaa aggtgtgatt tatagggagg attacttatg tttgaatttg aaacgcaact
     1921 aaaaaggtta aaacatgaag ttttaacagc agtagcaaga ctatctattg aagaaaattt
     1981 aacaaaagaa aatatagaaa aaattccata tgaaataatt aaaggagaaa aggcgagata
     2041 tagatgttgt gtttataaag agagagaagt agttcttgaa agggcgcaac ttgcattaag
     2101 tttaactcca aatagtaaat atggagatat aaatccagat tcagttagtt tggacacaga
     2161 tgagcaaatt atatatatag ttgaagcagc atgtgataga tgtccaataa atgaatttac
     2221 agttacagag ctttgtagag ggtgtttggc tcatagatgt aaggaagcat gtaaatttgg
     2281 ggcaatttct tatataaatg ggagagcata tataaatcat gatttatgta aggcttgtgg
     2341 aatgtgcaaa agttcatgtc aatatgatgc tatatcagaa gttgtaagac cttgtaaaag
     2401 cgtttgtcca acaggggctt tggattttaa tagaaacact atgaaagcaa tgatacatga
     2461 agataattgt ataaattgtg gagcatgtat gtcagcatgt ccttttggag caatatctga
     2521 taagagtttg atagcacctg ttgcaaaaaa acttgcaaag aaagaaaata tgtatgcaat
     2581 agtagctcca gctataacag gtcaaataga tagtaatatt acatatggtc agttaaaaaa
     2641 tgctataaaa tcactgggat ttgtagatat gatagaagct tcttgtggag cagatgcagt
     2701 tacagttcat gaaagcaatg aacttattga aagaataaaa tcaggagata attacatgac
     2761 aaattcatgt tgtccgggat tttttaagta tatagagaag atgttcccag atgaaaaaga
     2821 tagaatatca tctacagtgt ctcctatggt agcaacagga agattagtaa aaaaaataga
     2881 ttctgatgct aaagttgtat ttataggtcc atgtacagct aaaaagagtg aggcaacaga
     2941 gaaaagttta aaagattcag tagattatgt acttactttt gaagaactaa tggcattatt
     3001 tgaagcattt aatatagatt tatcaaaatg ttcaaatgaa gatataaatg atggttcgat
     3061 ttttggaagg ggatttggag catctggtgg acttgccaaa tcagtacaga actatattgc
     3121 tgaaaagggg cttagttttg attttgaacc tataaaagta tctggtccaa gacaaattaa
     3181 aaagacaatg acaatggcta aattgggaag attagaaggt aattttatag aaggaatgat
     3241 gtgtgaagaa ggttgtatta atggagcagg taagttttta tcaggtgtaa aagctaaaaa
     3301 tacttttgat agaaaaaatg gacaatctac taaaaagagt gttttatcta atgataagat
     3361 taaagaattt gaagatgtaa atttagaaag ataattgttt tggtacagtc atttttttat
     3421 catgttttta tcatgccaca aatatgccta aaatttgccc tttttatatg tgtattttac
     3481 agagttaagg ttgctatact ataaatatgt aataaataaa atttatagga gcttttggat
     3541 gaggaaaata gtattaaaag atatcctgtt tttagttact acattatcta taatagtaat
     3601 attattgctt gtaacaaata taactactaa tagtaagata aaatcaacaa gtgaatctta
     3661 tttaaaaagt gacaaaaata gtgtgaggca aaatggtatc cagaggagca caaagagtag
     3721 cacaaaaaat actgcattta agactactat actaaacact ggaaagtctg attgcatatt
     3781 ggttgagata ggtaacaaag tcataatgat tgatacagga gaagataaaa atggaaaaca
     3841 aatagtggat aggttaaaag aaaaaggaat aaatacactt gactatttaa ttttaactca
     3901 tttagataag gaccatatag gtggagtaga tagtgtgtta tctagtgtta aagtaaagaa
     3961 tattatacaa gcaaattata agaaagatag taagcaatat gatgaatata ttgactcact
     4021 taaaaaagct gatatagaac cagtgctact aaaagataat atgaatattg taatcaatgg
     4081 tgcagaaata aacatacatc cggcttcaaa aagcaagtac gagagttcaa atgattattc
     4141 aataatcact aatataagct atggagcaca taagttttta tttgcaggag atgcagagga
     4201 agaaagattg tcagagttta taaatggaaa tactttaaaa tatgattttg ttaaaatgcc
     4261 tcatcatgga agatatgaca aattaactga aacattttta gagtctattt caccccaata
     4321 tgctgttatt acatgttcag agaaaaaaga accagaggaa ggtgttttaa aaatattgga
     4381 aagattgaat ataaaaacat ttttgacttc taatggagag gtagttatca atagtgatag
     4441 taagacattg agtgtgaatc aataattttt ttaaaaatat ctaaaaaaat ttaaaaaaat
     4501 cattagcaaa tattacccct taaacatagt atattttagg agctgaaact ccacatacaa
     4561 aatgactagg aggtaacata ttatgttgga tagatttttt ggtgaaggcg gatttggtgg
     4621 atgtgcttgg tggataataa tattattctt cttattctta gcattccaag attgttgggc
     4681 tgaaatggac ttatgtgcat ggataccttt cttaatatta ttattaatac tttgtgaatg
     4741 tggtgacgtt tttgatggag gatgtggatg ctaaaaaaat caatttagat gatttaataa
     4801 agcttatggt gggtataaat aaaataccaa accaatcaca atctagtgtt tgaaggtagt
     4861 cggaaatccc ccgctacctt ctttttttta ttgttaaaat ttatttttga attatttcat
     4921 ttacatataa taatttttac gataaagtct gatataatta aaaagaaaat aaaatttatt
     4981 tataggagat gtaaaaatgg ctatagtgga taagattttc aatgagataa aacttatggt
     5041 tgcaagactt ttattgggaa aaaaatacag tgaatatgaa gaaaaagatt tagtgtataa
     5101 tacagaagaa gaagttatac ttataacttt aaaaagatta gtttttcagg gaaatgtaaa
     5161 cgaagcagaa gaaattttat ttgataaagc taagagtgta aatagtgaaa atatgcagta
     5221 tatagcaata gaattttata ctatgcttat ggaaaaaact gatgaagaat tagaagctat
     5281 gaatttttct aaacaagaag tttatcaagg tatagaagat attagaaaag tattgaattt
     5341 agaataaaag atatatgaaa atattgaaat aaattaatgc taaggtgaga atattatact
     5401 tatatataaa aatatagtat tcttatttta ttagttatat taggtatatc ttatttacca
     5461 taaaactatc ttgaaaaaaa ttaatcttaa ttgtataata ttactttgag tgaaaaagta
     5521 ttaacatttt tttataagat gttttactaa aaaaatatat ataaatatac tgttatcaat
     5581 aagaaattta atttagtgag gtgttaagat gaaagtagga tttgaccaca aaaaatattt
     5641 agaagagcag tctaaatata tcttagaaag agtaaataat tttgacaaac tttatttaga
     5701 gtttggagga aaattgatgg gagaccttca tgcaaaaaga gtacttccag gatttgatga
     5761 aaatgcaaag ataaaagtat tacaacatat gaaagaaaaa gttgaagttg taatttgtgt
     5821 ctatgcagga gatatagaaa gaaacaaaat aagaggagac tttggtatca cttatgatat
     5881 ggaagtttta agattaatag atgatttaag aggttatgaa ctagatgtaa atagtgtagt
     5941 aattactaga tttgaaggac aacctgctac aactgtattt ataaataaat tagaacgtag
     6001 aggaattaaa gtttataagc attatccaac aaagggatat ccgtcagatg ttgagactat
     6061 agttagtgat gagggatatg gagcaaatga atatatagaa actacaaagc caatagtagt
     6121 agtcacagca ccaggaccta atagtggaaa acttggtact tgtctaagtc agttgtatca
     6181 tgaaaataaa agaggtaatg tagttggata ttctaagttt gagacattcc cagtttggaa
     6241 tgtacctgta aaacatcctt tgaatatagc ttatgaagca gctacagttg atttaaaaga
     6301 tgtgaatatg atagattcat tccaccttga aacgtatggt gaaatgtcag taaactacaa
     6361 tagagatttg gaattatttc cagtgcttaa aaaaataata gaaaagataa ctggaaaaga
     6421 atcaattttc caatctccaa ctgatatggg tgttaataga gttggctttg gaataataga
     6481 tgatgaagta ataagaaaag cttctataga agaaataata agaagatact ttaaaactgc
     6541 ctgtgagtat aaaaagggac aagttgataa aggtgcttat gatagaatga aaatgattat
     6601 ggaagagctt aacttaaagc cagaagatag aaatgttgta ttacctgcta gaaactacag
     6661 taataaattg aaagaaagtg ccgacaagaa tgatacttgt cctgtagttg cattagaatt
     6721 agaagatggt acaatattaa ctggtaaggg ttctgattta atgaatggaa ccgcagcagt
     6781 agtattaaat gccattaaac atttagccaa tatatctgat gatatgcact taatatcacc
     6841 tgtaatatta gaacctatca taaacttaaa aacaaagact ttagctagta gaaatgtttc
     6901 acttagttgc caagaggtgt taactgcact tagtatttgt gctgtaacta atccaactgc
     6961 acaatttgct atggaaaagt tagcattatt aaaagggtgt caagctcatt ctactactat
     7021 attaaataga gatgatgaac aaacatttag aaaacttggt atagatgtaa cttgtgaccc
     7081 agaatatcct tcacaaaatc tttactatag ttaaaattat ataaaaaaat atgggctgtt
     7141 ttaaagtaat agtttgagca gtccattaca attataataa aatcagtagg ctgtcttgta
     7201 taagacagtc ttttgttttt aaaacatccc ataaattaaa tatatatact gttatccata
     7261 aggaatttta aatttagttc cttggaatac ctattgtaaa gcttttatat agtttttgca
     7321 agtgttttta aggatttttt ataaattata ttgaagttaa tggattatag atggttttat
     7381 ttatggaaaa tatgaatata taaagaaaat aatgaaaaaa taccaaaaag aaacataagt
     7441 ttggtataat taaaaagtaa tataaataaa attaatctat ttatacttta aaaggtgata
     7501 ataatgaaac attatagaaa aataattcat atagatatgg acgcttttta tgcatctata
     7561 gaacaaagag ataataaaaa attaaaagga agacctgtta ttgtcggtgg aaatccacaa
     7621 agccgaggtg tggttgcaac gtgttcttat gaagctagaa aatttggtat ccattcagct
     7681 atgccatcag ctgtagctta caataggtgt ccatatgcag tttttgtaag acctagattt
     7741 gatgtttata agagtgtgtc agagcaaata agagatatat tttatagata cacagattta
     7801 gttgaaccat tatctttaga tgaagcttac ttagatgtaa caaaaaataa aaaaaatatt
     7861 gattcatcaa ttgagatagc aaagcaaata aaaaaagata tatttagaga agttggtctt
     7921 acttcttcag ctggtgtgtc atacaataag tttcttgcta agattgcatc agacttaaga
     7981 aagccaaatg gattaactgt aataaccgaa gaaaatgccc aggacttttt agataaatta
     8041 cctgtgaata aattttttgg tgttggaaaa gttacttcaa atactcttaa aaatttaggt
     8101 ataaaaactg gatatgattt aaggtgttta aatttatttg aacttgaaaa tatattcaaa
     8161 aaaagaggtt atgaattata taaatttgct agaggaatag acgatagacc agtggaacca
     8221 aatagggtta gaaaatctgt tggggctgag actacattaa gtcataattt ggatattgat
     8281 gaagaagaaa cacgcaacat tcttgatgaa ctttgtgaag aagtatgtca tagattaaaa
     8341 aactctgaga agtttggaaa aacattaaca ttaaaaatta aatatgagga ctttacaaag
     8401 ataactagaa gccttagttt agaacactat attgacgaat ataatgatat aagaagtggt
     8461 gtagataatt tgttgagaaa tgttgaggtt aatggaaaac aaattaggct attgggagtt
     8521 acaatatcaa acctaagtga taaaaaagaa acttataaag atattacatt atttgaatac
     8581 atggatagta tccaaatgtg agttttgttt aaatgaaata acactagctt taatactata
     8641 taattgaggc tagtgttatt ttatgaatat ttttatattt tatatttttt gttttttgac
     8701 attatatatt atatactata tataaatact ttatatttgt agcaatattc agacaaatag
     8761 tgacctaaaa atcgtacttt gtttacataa ataaaatagt atgatataat tataaaaaca
     8821 acttataata ttgaagaagg ttgcttgttc gaaaaagggg atgataaatt atgatagaga
     8881 taagaaatgt aacaaaaaaa ataggaaata atgttatatt agatgatatt tctctagttg
     8941 tagaaacagg tacattggta gttttgattg gttcaagtgg ttgtggaaag actactactt
     9001 tgaagcttat aaacaaatta ataaaaccta catctggtga gatatatatt aatggcaaac
     9061 caatttctca ggaaaatgaa atagagctta gaagaaaaat aggatatgtt atacagaaca
     9121 caggcctatt ccctcatctt acaataaaag aaaatataga gctaattcca cgcctaaaaa
     9181 aggaaaaatc cgttgaagaa attgaaaaaa gaacgttgca actacttgag atggtaggac
     9241 ttgatagtga tgaatttttg aataagtatc cttcagaact tagtggtgga cagcaacaaa
     9301 gaatcggtgt tgcaagagcc attgctactg atgctgaaat aatattgatg gatgagcctt
     9361 ttagtgcttt agacccaata acgagaacat ctttacaaga acaattattt tctcttcaag
     9421 atgaattgaa aaaaactata atatttgtaa ctcatgatat ggatgaggct ttaaagatag
     9481 ctgataaaat ttgtattatg aaggatggaa gaatagcaca atatgatact cccgaaaata
     9541 tacttagaaa gcctgcaaat gactttgtaa aagattttat cggagaagat agagtttggg
     9601 ataatccaga atatataaaa gcaagagata ttatgataaa aaatcctatt gctgttaatt
     9661 ctactagaac tgtaactcaa ggaatagaaa ttatgagaac gagtaaggtt gatagcttac
     9721 taattataga tagagcaaaa acattaaaag gtattgttac tgtaaaagat atgaaagata
     9781 ttgatgataa gtcaatatta cttgctgata ttatgtcaag tgagcctttg catgtaaatg
     9841 aaggtgataa tttagtagaa atactaaatg taatgaatcg taattcggtt ggatatattc
     9901 cggttatttc tgatgaaaat aaactggtag ggcttattac tagaagtagt ttactttctg
     9961 ttttaagtga acaattctta gaaatggagg tgagtgttct tggctaattt ttttaacttt
    10021 atactattac aaaaagataa gattatagag cttttaatac aacatatgag tctaactgtt
    10081 acatctattt taatagctat aatagttggt gttcctcttg gaataattat ttcaagaatc
    10141 tcatctctta gaaagtttgt acttggattt gtaaacttag tccaagcagt tccgtctatg
    10201 gcacttttgg gtcttcttgt acctatactt ggtataggaa gtaaaccagc catatttatg
    10261 gtagtggttt attcattact accaattgta aaaaatacgt atataggtat aacaagtatt
    10321 gacccagtag tattagaatc agctaaaggt attggtctta caagaaatca gacattattt
    10381 aaaatacaat ttcctttagc gcttcctata ataatgggtg gagttagaat atctgcagtt
    10441 acagctgttg gtttgatgac tcttgcagca tttataggtg ctggtggttt gggatattta
    10501 gtattttcag gggttcaaac tgtaaataat aatatgattt tagcaggggc aatcccatca
    10561 tgtataattg cactgttagt tgattattta tttagtaaaa ttgaagttgc agttactcca
    10621 aaaggattaa atccaaaagc acctaagaag aattatatag cacttaaagt aatatctgta
    10681 gtggttgttg tttcaatgtt gttcgttgtt tttagttcta gtttttcaag taaaaaagat
    10741 acaataacta ttggttctaa agattataca gaacaactta tacttggtaa tgtttatgct
    10801 gaattagtag aaaaaaatac gaatcttaaa gttaagaaga atttaaatct aggtggttca
    10861 tctgttgcgt ttaatgcaat taaatctggt gagttagaca tgtatgttga ctatacaggt
    10921 acacttttgg taaatgtaat gaaacatgct ccgattaaag atgctgatga agcatataat
    10981 gttgtaaaag atactatgga aaaagaaaat cagttaactt tacttgaccc tcttggattt
    11041 aataatactt acacattagc tatgatgcct gaaactgctg aaaagtatgg aataaatact
    11101 atttctgatt tgactaaata tggtaaagaa tttacattct caccaacttt ggagtttgaa
    11161 aatagagaag atggtcttgt agggctttct agagattatg gtttaaaatt caaagatgta
    11221 aaagcaatga atggaagttt aagatataca gctttagata ataatgaatc tcaggttata
    11281 gatgcatttt taactgatgg tcttattaaa aagtttaatc ttaagatatt agaggacgat
    11341 aaaaatttct ttgtaccata ttatgcagca ccattagtaa gagaagatac tttgaagaaa
    11401 tatcctgagt tagaaaaagt tatgaatatg ctttcaggaa aaataaatga agaaactatg
    11461 agagaactta actatcaagt ggatgaactt ggtaaatcac cagaagaagt tgctcattca
    11521 ttcttagtta aagaaggctt agtataaaaa attaatagtt tatatcaaaa atttaaggga
    11581 gtgtctcaaa atgaactttt tagttcatga ggcactcttt tttatatgaa atcaaatata
    11641 ttttatcatt tcaacaataa aaaagaagat tatctttatt ttgagacagt ctcttatttt
    11701 tatgtatacc aaaaccatac ctacgatttt tatttataat taagtttcaa atagaatgaa
    11761 caagtacaac caattttgaa tataaatata gtaaatgtgc ttatatacga ttttattgtc
    11821 tggttgattg atattgatag atagctttct ttattgaatc gaagggaggg ggaatttgtt
    11881 atggataact ataagaaagt gaagcaagta ttgtggataa ttttatttgc taattttgca
    11941 gtagcattat taaaaatcat tattggtaat caaataaaaa gctatagtat gacagcagac
    12001 ggatttcatt ctttgtcaga tggagcatct aatatagtgg ggcttatagg tattttcttt
    12061 gcatctaaac caaaagataa aaatcatcct tatggacata aaaagtttga aattataacc
    12121 agtttattta taagtggtat gttgtttgtt atagcaatta agataattct tagtgcagtg
    12181 ttaagaatag ctaatccagt tgtacctgct ataactatag aaagtttaat tgctttaatt
    12241 attacacttt ttataaatat ttttgtatgc atgtatgaat atagaattgg gactaaacta
    12301 aatagttatg ttttgatttc ggattcattg catacaagaa gtgatatatt tgtgtctcta
    12361 ggtgtattgg ttactttagt tggtgttaag ttaggatttc cagtaataat agaatctata
    12421 gttcctatta ttatttctgc attcataatt tattcggctt atggaatatt taggccatct
    12481 attggaattt tggtcgatag agtggctgta gatgaggatt atataaaaga aattgtgttt
    12541 gaatttaatg aggtaaggga tgttcacaat atcagaagta gaggtagcaa aagttctatt
    12601 tatattgaca tgcatgtaat ggtagatcca tttataagcg tagagcaatc tcatgattta
    12661 acacataaaa ttgagaaaca aatacaagaa gaaattaatg aaaatgctca agtaatagtc
    12721 catattgaac ctttttatag tttttaactt agttataaaa tacaagttat aaaaaaatat
    12781 aattt
//
LOCUS       DAMKNB010000095        12552 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.101, whole genome shotgun sequence.
ACCESSION   DAMKNB010000095 DAMKNB010000000
VERSION     DAMKNB010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 12552)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12552)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12552
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.101"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            117..398
                     /locus_tag="PC494_003081"
     CDS             117..398
                     /locus_tag="PC494_003081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3913560.1"
                     /translation="MASKQIPRNNLEKFLRIRVLSHTGDKIHIKLPVNFAKRMIENNA
                     LDLFNGKDDVVDGKKVTEILVKAFDYDLTGEVVHLERKNGDIIKVSIVQ"
     gene            662..916
                     /locus_tag="PC494_003082"
     CDS             662..916
                     /locus_tag="PC494_003082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3913561.1"
                     /translation="MENKDFKLTICIFAFVIGVVVLFCCIGLGEFSAEHIIQQNGGIM
                     DTDQYNIYLDQSISQYRNFGSILALLGGIGILFDKYIRKY"
     gene            961..1284
                     /locus_tag="PC494_003083"
     CDS             961..1284
                     /locus_tag="PC494_003083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3913562.1"
                     /translation="MATEIFTVKITPLEAQKMIKENLDADLVFSDSYNLGDDKFILIT
                     TFEKYYARNNSDAGLIVVYENTTGKTVIKATSTGSAIGILKIDWGAGGNLLKRVKNIL
                     ADYII"
     gene            complement(1578..2429)
                     /locus_tag="PC494_003084"
     CDS             complement(1578..2429)
                     /locus_tag="PC494_003084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase subunit GatY"
                     /protein_id="HDF3913563.1"
                     /translation="MALVTTTSMLKKAQDEGYAVGAFNVENMEMVIAVIEAAEELNSP
                     VILQTTPSTVKYAGLDYYLANAKVAAERVNIPVAMHLDHGSSFDLAMKALRSGYTSIM
                     IDGSHESFENNISISKSVVKACSPSLIPVEAELGKVGGKEDDLDGGNSNDYTNPKEAK
                     EFVDRTGISSLAIAIGTAHGLYKGEPKIDLDRLSEIKNVVSIPLVLHGGSGIHDDIIK
                     EAIKRGIAKVNYATELRIAYSKGVKKVLDEDSEVIDPKKYGLAGLQSVKDFVKEKIKV
                     CGSVNRV"
     gene            complement(2478..3647)
                     /locus_tag="PC494_003085"
     CDS             complement(2478..3647)
                     /locus_tag="PC494_003085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HDF3913564.1"
                     /translation="MKMFKLEEQKLKDLGAIITTNEIKQQPELWLETYEIYKSNKEKL
                     SRFIDTISNNHGQFRVIFTGAGTSAYIGNSILPYLKNKNDIRKYIFEAIPTTDIVSNP
                     YDYLKKDIPTLLISFARSGNSPESLAALNLGNKIVDNFYHLAITCNPEGELAKMTKND
                     ENNYLLLMPSKSNDEGFAMTGSFSCMMLSAMLIFDSLEDDVEKSYINAIIEMGRNVID
                     RKDEIHELINKDFDRVVYLGSGGLGGLTQEAQLKLLELTAGKISTVYDSPMGFRHGPK
                     SFIDENTLVFEFVSNCLYTRKYDLDVLEEIKRDKIAKFTCAVSVENENNFSGTKFEFK
                     EKYNKLPDVYLAMPYILFAQTIALFVSVKVGNKPDTPSATGTVNRVVKGVTIYEY"
     gene            4118..5035
                     /locus_tag="PC494_003086"
     CDS             4118..5035
                     /locus_tag="PC494_003086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HDF3913565.1"
                     /translation="MKNIKMGMIGLGSIAQKAYLPILTKSERFEFVGAFTPNKVKREK
                     VCSDYRIMPFDSIESLAKKCDCIFLHSSTETHYEIIKILLNLGVHVYVDKPLASTVSQ
                     GEELIELSTKKNLNLMVGFNRRFCPMYKEIKNNATEIVSINICKHGLNSLRNVRFDST
                     LIDDYIHVIDTALWLANEDVEISGEDLFLTDNKNLIFVSHKLKGKNFSINTSMHRDSG
                     TKLEQVEILSKGKIQRVKNLNVLEIEEGGNLTLKQSGAWVNILKQKGFEDISNHFIDC
                     IENNIKPAINGEECIKAQRLLEKIINSVK"
     gene            complement(5164..6093)
                     /gene="pfkB"
                     /locus_tag="PC494_003087"
     CDS             complement(5164..6093)
                     /gene="pfkB"
                     /locus_tag="PC494_003087"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HDF3913566.1"
                     /translation="MITVITFNPSIDRMYRVNNINIGEVQRVVSKNATAGGKGLNVAK
                     VCKILKENPLAMGFLGGFNGEFIKNELRKLDIQNKFTKIEQETRNCLNIIEDNKVSTE
                     FLEKGPIVEKSDLERFENDIEEVLKNTKILVASGSYCENMPIDYYEKIGNTCRANNIK
                     FILDTSGEALKIALKSKPYLIKPNIDEIRHLLGMNIESREEIILSGKKLIEMGAENVC
                     ISLGKDGMVYLNEDNVYDVKVPVVKCINTVGSGDSTVAGFSVGILRGYKIENLLKFAN
                     ACGISNALNMETGFVDLGEIDKYQDLVEVKKLS"
     gene            6360..7085
                     /locus_tag="PC494_003088"
     CDS             6360..7085
                     /locus_tag="PC494_003088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDF3913567.1"
                     /translation="MIKRNDKRPIYDQLVEILRTKIENEMEPNDRMLSERKICDEYGV
                     SRTTVRLAMAELEHMGYIYKRHGKGTFVAALSQNSQNLMESYSFTDYMRTQGKKPGTK
                     VLSFEVVESTKYFSEKLGITTGEKMIKIMRLRLADDLPMMLERTYLPMKEFIGLTKEK
                     IEQKPLYEIFREDYGEIIKVADEEFSAGIISDKEAKLLEVPGDSPCLKLLRTTYNDDN
                     IVIEFTLSVARSDKFVYRVRHVR"
     gene            7168..8322
                     /gene="nagA"
                     /locus_tag="PC494_003089"
     CDS             7168..8322
                     /gene="nagA"
                     /locus_tag="PC494_003089"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HDF3913568.1"
                     /translation="MKSFIYADKFFMKHGIKEKGYLSIINGKFGEFQQERPNNTDNVI
                     DFSGKYIAPGLVDTHIHGLLGADVMDNTFEAINTISKGLLKYGVTSFLPTTLTDSVDT
                     LSDSVENISNSFNRVEGAKIQGIYLEGPFFTEKYKGAQNEKYFKDPDINILKLWQKKS
                     KNLIRKIAIAPERKGSIELTRYATKNNISVSLGHSSATFEQVKQVVNSGAKVFVHTYN
                     GMSPLNHREPGMVGAAMVLKDTYAELICDGHHVSPIAVKIMMDAKSSNNIALITDCMR
                     AGAMEDGKYTLGKFNVNVKNSVARLNSGSLAGSVLTMDKAVRNIVDWNISTLEDAIKM
                     ATYIPALSCNIDNVCGSIYQGMDADFIVTDNDFNIHETYINGICMYKVNK"
     gene            complement(8505..9662)
                     /locus_tag="PC494_003090"
     CDS             complement(8505..9662)
                     /locus_tag="PC494_003090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S41 family peptidase"
                     /protein_id="HDF3913569.1"
                     /translation="MYLVISKKKAIFLGVILVIITAMVTSAFQLTLGNKVVISKELYE
                     DYKKYDKLLGLESIIKQDFYKKVSDTDLVNGAAKGLFLGTNDKYSGYYTKDEMENLIN
                     DSEGSYVGVGMYIGASKDGGLVVVPMKDSPAEKAGVKSGDKLVKVNGKSVSYKNSDEA
                     VRMMKGKKGKTVELTILREDKQLNFKVKTDQIIEKSIESKVIDNDLGYIEITQFISST
                     YTDFDKALKELKAKNIKGLVIDLRNNPGGMLDICKEVADELIGEGTIVYTKDNKGNTE
                     YLKSDKEKLGLPIVVLTNGESASAAEILTAAIVDNKEGISVGTTTFGKGLVQSVVRLK
                     DGTGYKLTTAQYFTPNGDYINEKGIKPTIEEKDENKQLDVATKWLREQIDK"
     gene            9816..10385
                     /locus_tag="PC494_003091"
     CDS             9816..10385
                     /locus_tag="PC494_003091"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HDF3913570.1"
                     /translation="MKKEFRKKVIESRKNKSANFVLSNSNLITEKLLQMEDIRNATNI
                     MLYLNFNNEVQTDNLIKKLLSLKKIVSSPITIKENHTLIPTQITDLKEGLRIGAYGIR
                     EPNEKSPTIDIKALDVVIVPAVAYDIHCYRLGYGGGFYDRFLENLRKDAITIGIAFDF
                     QIFDSIPKETHDAQLDYIVTETRIITPNS"
     gene            complement(10567..10983)
                     /locus_tag="PC494_003092"
     CDS             complement(10567..10983)
                     /locus_tag="PC494_003092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3913571.1"
                     /translation="MNVKFNIKGIIYGVIALVFVIGGFIFIPSMFVEKSKPIDYTVLQ
                     RNSIPEKILDVMDKYTNEERALAAKIDNKIYIIVTRGNNKYGIEMDKIESVVEEGKDV
                     LRVKIKYKDKEDSFPYIVVETNMSELPDRIELNATK"
     gene            complement(11209..12303)
                     /locus_tag="PC494_003093"
     CDS             complement(11209..12303)
                     /locus_tag="PC494_003093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3913572.1"
                     /translation="MSEKVNVKTVISFAGAYVATVIGSGFATGQEIMQFFSFYGFAGI
                     IGGIISMVLFSWMGASVMSKGKELQLKEPIKIYRVYCGKYLGIFFEWFGPLFLFGVFV
                     VMISGAGATLTEYYGLNPFVGRVGMAVVALLTVSLGLDKLSKILGGIGPIIIIFTLLV
                     GGISLAKNIGNIGEAAQVLSTVKIAKPVPNAYLSGVIYTTYNTIVVMAFLTGLGASAA
                     NKKEAICGGILGGVALMAAAIMMHLAILSDIGNLYSKAIPSLFLADKISPVIGVLFSI
                     ILILGIYTTAVPLLWSVTNRFVDDKHPKFKLITLIAAILGLIGGFLPFDKLVGILYPY
                     TGYMGVIILVCVLYRQITKTSGYQEGISDK"
BASE COUNT         4476 a         1889 c         1580 g         4607 t
ORIGIN      
        1 aatataaaac aagattagaa aataatagtg ttactttcat aataaataca tataaagata
       61 tttttaagaa taaaatttat tattaaataa aaaataaagg agagtgattt aatagcatgg
      121 catcaaaaca aataccaaga aacaatttag aaaagttttt aagaataaga gtcttatcac
      181 atacaggcga taaaatacat ataaagttac ctgtaaattt tgcaaagaga atgattgaga
      241 ataatgcttt ggatttattt aatggaaaag atgatgtagt agatggtaaa aaagttactg
      301 aaatattagt taaggcattt gactatgatt taactggaga agtagttcac ttggagagaa
      361 aaaatggaga cattattaaa gtttcaattg tacaatagaa ttattttata tgaattttat
      421 ttttgaatag ttataaataa ttagaaattt gtaaaaaagt ataatatatt attagtaatg
      481 gtacagaata cacatttata atttatagat gtgtattttt tgtttaaaaa atttaaatat
      541 ataaaactat aaaggttaca attttggaaa tagatgtaaa tatatgttgt attgtataat
      601 aagagtaata taaaatctag taaaaataat caaataaatt tagcttatga gagggataac
      661 tatggaaaat aaggatttta aattaacaat atgtatattt gcttttgtaa ttggagtagt
      721 agtattattc tgttgtatag gtttaggtga atttagtgca gagcatatta ttcaacaaaa
      781 tggtggaatc atggatactg accaatataa tatttatcta gaccaatcta tttctcaata
      841 tagaaatttt ggttctatat tagctctgtt aggaggaata gggatattgt ttgataaata
      901 tatcagaaaa tactagagat tatgttttgt ctaaaataaa ttcttatgag gagataaaaa
      961 atggcaacag aaatatttac tgtaaaaatt acacccttag aggcacaaaa aatgataaaa
     1021 gaaaatcttg atgcagattt agtttttagt gattcttata atttaggaga tgataaattt
     1081 atactaatta caacttttga gaagtattat gcaagaaata atagtgatgc aggattaata
     1141 gtagtttatg aaaataccac aggaaaaaca gttattaaag ctacttcaac aggcagtgca
     1201 attggaattt taaaaattga ttggggtgca ggtggaaatt tacttaaaag agtaaaaaac
     1261 atacttgctg attatattat ttaattattt tatctaactg ataatatgtc aagaaaatct
     1321 cgtaaaagag gttaagaaca tttttataat atatagataa ataagaattt gaaggtaaag
     1381 tttttaaggt ataaagaaaa ataatataat aaaacgaatt ggctttataa ttctttataa
     1441 ggcaaagagc acatttcttt atataattgt tggatattaa ataatatgta aatacaccat
     1501 ttacatataa ttaatataaa tttttcatat aataaatatc ctaaacttat ctaaaataaa
     1561 tttaggatat tttattttta tactctattt acagacccac acactttaat cttttctttc
     1621 acaaaatcct ttactgattg aagccctgct aatccatact ttttagggtc tataacctca
     1681 gaatcttcat ctaaaacttt tttaacccct ttactatatg caattcttaa ttcagttgca
     1741 tagttaactt ttgcaatacc tctttttata gcttctttta taatatcatc atgtattcct
     1801 gaacctccat gcaatactaa aggtattgaa actacatttt taatttctga taacctatct
     1861 aaatctattt taggttcacc cttatacaat ccatgtgcag tacctatagc aatagccaat
     1921 gaagatattc ctgttctatc gacaaactct tttgcctctt ttggatttgt ataatcatta
     1981 ctattcccgc catctaaatc atcttctttt ccaccaactt tcccaagttc tgcttccact
     2041 ggtataagag aaggactaca tgcttttact actgatttag atatagatat attattttca
     2101 aagctttcat gagaaccatc tatcattatt gatgtatatc cacttcttaa agctttcatt
     2161 gcaaggtcaa aacttgaacc atggtccaga tgcattgcta caggtatatt tactctttct
     2221 gcagcaacct ttgcatttgc tagataataa tcaagacctg catattttac agtagatgga
     2281 gtagtttgta atattactgg agaatttaac tcctcagcag cttctataac agcaattacc
     2341 atttccatat tttctacatt aaatgctcct actgcatacc cttcatcttg tgccttttta
     2401 agcattgatg ttgttgttac taatgccaca ttgataccct cccaaattat ttagttataa
     2461 tattttaatc ttatctttta atattcatat attgttacac cttttactac tcgatttact
     2521 gttcctgtag ctgatggagt atctggctta tttccaacct ttactgatac aaacaatgct
     2581 atagtttgtg caaacaatat gtatggcatt gcaagataca catctggtaa tttattatac
     2641 ttttctttaa actcaaactt tgttcctgag aagttatttt cattttctac tgacactgca
     2701 caagtgaatt tagcaatttt atcccttttt atctcctcta aaacatctaa atcatatttt
     2761 cttgtatata aacagttaga tacaaattca aatacaagtg tattttcatc aataaatgat
     2821 tttggtccgt gtctaaaccc cataggagaa tcatacactg tagatatttt tcctgctgta
     2881 agttctaaaa gttttagttg tgcttcttgt gtcaaaccac ctaatcctcc tgaacctaaa
     2941 tatacaactc tatcaaaatc tttatttatt aactcatgta tttcatcttt tctatctata
     3001 acatttcttc ccatttcaat tattgcattt atatatgact tttctacatc atcttctaaa
     3061 ctatcgaata ttaacatagc agataacatc atacacgaaa aacttcctgt catggcaaag
     3121 ccttcatcat ttgattttga tggcattaat aacaagtaat tattttcgtc gtttttagtc
     3181 atcttagcca gttctccttc tggattacaa gttatagcta aatgataaaa attatctaca
     3241 atcttattcc ctaaatttaa agctgctaaa ctttcaggac tatttccact tcttgcaaat
     3301 gaaattaata atgttggtat atcttttttt aagtaatcat atgggtttga aactatatcc
     3361 gtagtaggta ttgcttcaaa tatgtatttt cttatgtcat ttttattttt aaggtaagga
     3421 agtattgaat ttcctatgta agctgaagtt ccagcacctg taaatataac tctaaactgc
     3481 ccatgattat tacttattgt atctatgaat ctacttaatt tttctttgtt agatttatat
     3541 atttcataag tttctaacca taattcaggc tgttgtttta tttcattagt tgttattatt
     3601 gcacctaaat cttttagttt ttgttcttct aatttaaaca ttttcattct cctttcatac
     3661 ttgtaacgtt tacatttggt aatgaggtta taaccacttt aaactataaa aaaatatact
     3721 cttttataat tttttgctta gattttttag tactacttaa actcactata aaatatacac
     3781 tatagatttt aattaatttt atagtttatc tttaaaaatt taataaaatc atactctata
     3841 tactttagta tttttatttt acgataaaag cttgttcaga ccaaagtggt aattaccact
     3901 aatccaaata taaattaatt tgaatttttt gtcaatacat aaaatattta tatcaatcaa
     3961 ttttatggat atcctacaaa attactttat caatatttct tatttcgcta atttacttat
     4021 ataagcttta aatttatttt ttgatacaaa gtttacaaat ttatgtgtct gaattataat
     4081 caattctgta aatataaaaa ccttaggaga aagtattatg aaaaatataa aaatgggaat
     4141 gataggtctt ggctccatag ctcaaaaggc atatttacct atattaacta agtctgagag
     4201 atttgagttt gtaggagctt ttactccaaa taaagttaaa agggaaaaag tctgtagtga
     4261 ttatagaatc atgccattcg attctattga atccctagct aaaaaatgtg attgtatttt
     4321 tctacatagc tctacagaaa cacactacga aattataaaa atattattaa atttaggtgt
     4381 tcatgtatat gtagacaaac ctcttgcttc aacagtaagt caaggagaag aacttatcga
     4441 gttaagtacg aaaaaaaact taaatttaat ggttggattc aaccgtagat tctgtcctat
     4501 gtacaaagaa attaaaaata atgctacaga aattgtatct atcaatatat gtaaacatgg
     4561 attaaattcc ttaagaaatg ttagattcga cagtactctt atagatgact atatacatgt
     4621 tattgacact gctttatggt tagcaaatga agatgttgaa attagtggag aggatttatt
     4681 tttaacagac aataagaatc ttatatttgt aagtcataaa cttaaaggta aaaatttctc
     4741 tataaacacc tctatgcata gagattctgg aacaaagtta gaacaagttg aaattctttc
     4801 aaagggtaag attcaaagag ttaagaatct taatgtactg gaaatagaag aaggtggaaa
     4861 cctaacttta aagcaaagtg gtgcatgggt aaatatatta aaacaaaagg gttttgagga
     4921 tatatcaaat cattttattg attgtataga aaataatata aaaccagcta ttaatggaga
     4981 agagtgtatc aaagctcaaa gattactaga gaaaattata aattcagtaa aatagatatt
     5041 tattataaaa ataggttaaa aatgaatttt tctaacctat ttttatataa gactatatct
     5101 tttatattaa aattaaaatc tattacaaca acattaaatt tattatattc ccattaaatg
     5161 tatttaactt aactttttta cttcaactaa atcttgatat ttatcaattt ctcccaaatc
     5221 tacaaatcca gtttccatat ttaaagcatt acttatacca caagcatttg caaatttaag
     5281 taaattttct attttataac cccttaaaat acctacacta aatccagcca ctgtgctatc
     5341 tccactacct acagtattta tacactttac aactggtact tttacatcat atacattatc
     5401 ttcgtttaaa tacaccatac catcttttcc taaagatata catacattct ctgcacccat
     5461 ttcaataagt ttttttcctg acaagataat ttcctctctt gattctatat tcattcctaa
     5521 taaatgtctt atttcatcta tatttggttt tattaaatat ggttttgatt ttaaagctat
     5581 ttttaatgct tctcctgatg tatctaatat aaactttata ttatttgctc tacatgtatt
     5641 tcctatcttt tcataatagt ctatcggcat attctcacaa taactaccag aagctaccag
     5701 tattttagta ttttttagta cttcctctat atcattttca aatctctcta aatcgctttt
     5761 ttctactatt ggtccttttt ctaaaaattc tgtactaact ttattgtcct caattatgtt
     5821 taagcaattt ctagtttcct gctctatttt tgtaaattta ttttgtatat ctagttttct
     5881 aagttcattt tttataaatt ctccattaaa tccgcctaga aatcccatag ctaaaggatt
     5941 ttcttttaaa attttacata ccttagctac gtttaatcct ttacctccag cagttgcatt
     6001 cttacttact accctttgca cctcacctat gtttatatta ttcactctat acattctatc
     6061 tatagatggg ttgaatgtta ttactgtaat catactagat tctcctcatt attaattttt
     6121 acttttctaa acaataaatt aatctgtaaa ataaaaaata cctcatataa tatatccaaa
     6181 gtggttatta ccaatttgaa tataaattat tttacttgtt ttgtcaatgt accataattt
     6241 tataataaat taatagcctt acttattgaa ttttgattaa actttattca ttgacataaa
     6301 taattctata ttctataatc aaattgtggt aataaccact tagaaaggac tatattttta
     6361 tgataaaaag aaatgataaa agaccaatat atgaccagct tgttgagata ttaagaacta
     6421 agattgaaaa tgagatggaa ccaaacgata gaatgctttc cgaaagaaaa atttgtgatg
     6481 aatatggagt aagtagaacc acagttagac tagctatggc tgagttggaa catatgggat
     6541 atatatacaa aagacatgga aaaggaactt ttgttgctgc actaagtcaa aattctcaaa
     6601 acttaatgga aagttatagt tttacagatt atatgagaac acaaggaaaa aagccaggta
     6661 caaaggtatt atcatttgag gtagtagaaa gtacaaagta tttctctgaa aaattaggta
     6721 taactactgg tgaaaaaatg ataaaaataa tgcgtttaag acttgctgat gaccttccta
     6781 tgatgcttga aagaacatat cttcctatga aagaatttat aggattgaca aaagaaaaaa
     6841 tcgaacaaaa acctttatat gaaatattta gagaagatta tggcgagatt attaaagttg
     6901 ctgatgaaga attttcagct ggaataatct ctgataagga agctaagtta ttggaagtac
     6961 caggagattc accttgtctg aaattacttc gtaccacata taatgatgac aatatagtta
     7021 ttgaatttac tttgagtgtc gctagaagcg ataaatttgt atatagagta agacatgtaa
     7081 gatagtaagt taaatagctt tcaagaaaac agaatgatat tataagcgtc aatgccacaa
     7141 tgatagtata attataagga ggttattttg aaaagtttta tttatgcaga taaatttttt
     7201 atgaaacatg gaatcaaaga aaaaggttac cttagtataa ttaatggcaa attcggtgaa
     7261 tttcaacaag aaagacctaa taatactgat aatgttatag atttttcagg taaatatatt
     7321 gctcctggct tagttgatac tcacattcac ggtcttttag gtgcagatgt catggacaat
     7381 acatttgaag caataaacac aatttcaaaa ggcttattaa aatatggagt aacatctttc
     7441 ctacctacaa ctttaactga ttctgtagat acactaagtg attctgtaga aaatataagc
     7501 aatagcttca atcgagttga gggtgcaaaa atacaaggga tttatttaga aggtccattt
     7561 tttacagaaa aatataaggg cgctcaaaat gaaaaatatt ttaaagaccc tgacatcaat
     7621 atattaaaat tatggcaaaa aaaatcgaaa aatttaataa ggaaaatagc aattgctcca
     7681 gaacgtaaag gttcaataga attaacaaga tatgcaacta aaaataatat atcagtttct
     7741 cttggtcata gttcagctac atttgagcaa gttaaacaag tcgttaattc aggtgctaaa
     7801 gtgtttgtac atacatataa tgggatgagt cctttaaatc atagagaacc tggaatggtt
     7861 ggggctgcta tggtactaaa agatacttat gctgaattaa tttgtgatgg tcatcatgta
     7921 agcccaatag ctgttaaaat aatgatggat gctaagtcta gtaataacat agctttaatt
     7981 acagattgta tgagagctgg tgctatggag gatggaaaat atactcttgg taagtttaat
     8041 gtaaatgtaa aaaatagtgt tgcaagatta aatagtggga gtttagctgg aagtgtatta
     8101 actatggaca aggctgtgag aaatatagtt gattggaaca tatcaacttt agaagatgca
     8161 ataaaaatgg ctacatatat ccctgcttta agttgtaata ttgataatgt ctgtggctct
     8221 atatatcaag gtatggatgc agactttata gtaacagata atgactttaa tatacacgaa
     8281 acttatataa atggtatctg tatgtacaaa gttaataaat agattcaata taaagttata
     8341 gaggcttcct aaaaatagag ataagcctct ttttcattgt taaaatgatg aaaatacatt
     8401 tgatttcata caaaaagagt gcctcatgaa ctaaaaagtt cattttgaga catctctttt
     8461 ataatgttct ttattttata gtataagttt ataaaaatta aatcctattt atcaatctgt
     8521 tctctaagcc acttagttgc tacatctaac tgtttatttt catctttttc ttcaatagta
     8581 ggctttatac ctttttcatt gatataatct ccattaggtg taaaatattg agcagtagtt
     8641 aacttgtatc ctgttccatc cttcaatctt acaactgatt gtaccaaccc tttaccaaaa
     8701 gttgtagtcc ctacagaaat accttcttta ttatcaacga ttgcagctgt taatatttca
     8761 gcagcagaag cactttctcc attagttaac actactattg gaagtcccaa tttttcttta
     8821 tcagatttca agtactcagt atttccctta ttatcttttg tatatactat ggttccttca
     8881 ccaattaact catcagcaac ttctttacat atatctagca ttccaccagg attatttcta
     8941 aggtctatta ctaatccctt gatatttttt gcttttaatt cttttaaagc tttatcaaag
     9001 tcagtatatg tacttgatat aaattgggta atttctatat atcctaaatc attatcaatt
     9061 actttacttt ctatactctt ctcaattatc tggtctgttt ttactttaaa gttcaattgt
     9121 ttatcttctc ttaatatagt cagttcaact gttttacctt ttttaccctt catcatacga
     9181 acagcttcat ctgaattttt atatgagaca gattttccat tgacttttac taatttatcc
     9241 cctgatttta cacctgcttt ctctgctgga gaatctttca tgggaactac tactaagcca
     9301 ccatcttttg atgcccctat atacatacct acaccaacat aagaaccttc actatcatta
     9361 attagattct ccatttcatc tttagtataa taaccagaat acttatcatt tgttcctaga
     9421 aatagacctt ttgctgctcc atttaccaaa tcagtatctg atactttttt ataaaaatct
     9481 tgttttataa tagattctag tcctaacaac ttatcatatt ttttatagtc ttcatagagt
     9541 tctttcgata ttacaacttt attccccaat gtcaactgaa atgctgatgt aaccatagct
     9601 gttataatta ctaaaatcac ccctaaaaaa atagctttct tctttgaaat cacaagatac
     9661 atctcctttt acataaacta ttattattat atgactagct gttattttta ttacatttac
     9721 ccaaatatat tgctttatta caataaatta tactaaaatt tatattaaat acaattgctg
     9781 tacacattat aacatattaa gggaggaatt attttatgaa aaaagaattt agaaaaaaag
     9841 ttattgaatc aagaaaaaat aagagtgcaa actttgtact tagtaattca aatttaataa
     9901 ctgaaaaatt acttcaaatg gaagatataa gaaatgcaac taatataatg ctttatctaa
     9961 attttaacaa tgaagttcaa acagataatt taatcaaaaa acttttgtct ctaaagaaaa
    10021 tagtatcaag tcccatcaca ataaaagaaa atcatacatt aatccctact caaataacag
    10081 atttaaaaga gggattgaga attggagcat atggaataag agaacctaac gaaaaatcac
    10141 ctacaattga tattaaggct ttagatgttg taattgtacc agctgtagca tatgatatac
    10201 attgctatag attaggatat ggtggaggat tttatgatag atttttagaa aacttaagaa
    10261 aagatgctat aactatcggc atagcatttg acttccagat attcgattct attccaaaag
    10321 aaactcatga tgcacaatta gactacatag ttactgaaac tagaattatc actccaaata
    10381 gttagaatat taagtatttc cagaccccat ttaatgtagt aataaatact actgttaata
    10441 tcttacttta taagcatttt aagtcatggc ttttacaaca ataagaacca tacacaattt
    10501 acttacatta ataaaaacca tgactttatt gtacaatatg cagttattta attataaaat
    10561 accttcttat ttcgtcgcat ttaattctat tctatctgga agttcactca tatttgtttc
    10621 aacaactatg tatggaaaag aatcttcctt atctttatac tttatcttga ctctcaaaac
    10681 atcctttcct tcctcaacca cactttctat tttgtccatt tctataccat atttattatt
    10741 tcctctagtc actataatgt atattttgtt atcgatttta gccgctaatg ctctttcttc
    10801 atttgtatac ttatccatca catctaatat cttttctggt attgaatttc tttgtaatac
    10861 tgtataatct atgggtttag atttctctac aaacatactt ggtatgaata taaatccccc
    10921 tataacgaat acaagagcta taactccata aattatacct ttaatattaa actttacatt
    10981 caatcttatc actcctccca tatattctaa atatatgatt tataaactta tcttagactc
    11041 taaattattg attagtatat atttatacat aattataaat atatgtaatg taactaaaaa
    11101 acatgttttt tctatttcat aataaacgag ctaaaaaata aaaagagcta tatgaaaaca
    11161 ttttcattgt tttcatatag ctcttgagtt tacaatatta aaaaatactt atttgtcact
    11221 gattccttct tgatatccag atgtttttgt aatctgtcta taaagaacac aaaccagtat
    11281 tatgacgccc atatatccag tatatggata taaaatacca accagcttat caaatggtag
    11341 gaagccacct ataagaccta atatagctgc tattaaagtt attaatttaa acttaggatg
    11401 tttatcatct acaaatctat tagttactga ccataataaa ggtacagctg ttgtatatat
    11461 acctaatata agaattattg agaataaaac tccaattact ggtgaaatct tatctgctaa
    11521 gaataatgat ggtattgctt ttgaatataa gtttcctata tcagaaagaa tagctaagtg
    11581 catcattata gctgcagcca taagtgctac tccacctaat ataccaccac aaatagcttc
    11641 ttttttgtta gcagcacttg ctcctaatcc agttaagaat gccataacaa caattgtgtt
    11701 ataagtagta tatattacac cagatagata ggcatttgga actggtttag ctatctttac
    11761 agtgctaaga acttgtgcag cttctcctat attacctatg tttttagcta aacttatacc
    11821 accaactaaa agtgtaaaga ttattattat aggccctatt ccacctagta tctttgataa
    11881 tttatcaaga cctagtgaaa cagttaataa tgctactact gccataccta ctctacctac
    11941 aaatggattt aatccatagt attcagttaa agttgctcct gctcctgaaa tcattactac
    12001 gaaaacacca aataagaata aaggtccaaa ccattcaaag aatattccta aatacttacc
    12061 acaataaaca cgataaattt tgataggttc tttaagttga agctctttac cttttgacat
    12121 aactgaagca cccatccatg agaataatac cattgaaatt atcccaccaa taatacctgc
    12181 aaaaccataa aaagagaaga attgcattat ttcctgtcct gttgcaaatc cagaaccgat
    12241 tactgttgct acatacgcac ctgcgaaact gatgactgtt ttaacattta ctttttctga
    12301 catatctcag ttacctcccc atgtgaaatt ttttcttctg attaaacaat tcgataaact
    12361 acctacaatt tcctttaaca taaaatacat gataactgtt ttatagcttt ttagtataat
    12421 aacttaaaac ttataatctg attttatacc ctactcctcc tctcataatt ttttttagat
    12481 tcttttatct aagtagtcat tatatataaa attagtttct ctataaatta tatattagtc
    12541 atatttttct ga
//
LOCUS       DAMKNB010000096        12318 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.102, whole genome shotgun sequence.
ACCESSION   DAMKNB010000096 DAMKNB010000000
VERSION     DAMKNB010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 12318)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12318)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12318
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.102"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            <1..321
                     /locus_tag="PC494_003094"
     CDS             <1..321
                     /locus_tag="PC494_003094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HDF3913573.1"
                     /translation="VEKADCYTGNTIESERFFPGWLYDEEDEFVQAAYKGLKEAGIDS
                     EITQYSFCTNGSHYAGEAGIRTIGFGPSKENLAHTIDEYIELDQLFKGTEGYYGILKS
                     VYKK"
     gene            337..1920
                     /locus_tag="PC494_003095"
     CDS             337..1920
                     /locus_tag="PC494_003095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-aminoacylase"
                     /protein_id="HDF3913574.1"
                     /translation="MRTLIKHGLIVDGNKTPAYEGDILIENEKILKISQDLNEEADKV
                     IDAKGRVICPGFIDTHSHSDLVILVNPYNEVKIRQGITTEVLGQDGISMAPLPQEHIS
                     SWRKNLAGLDGESDEIDWKYETTENYLKMMDYNGVGLNETYLVPHGNVRMEAMGLEDR
                     PATKEEIQKMCEITERELKAGAIGLSTGLIYIPCAYSLTEEIIEMCKVVAKYDGVFVV
                     HQRSEADTILTSMEEIIEIGKQSGVKVHFSHFKVCGKANWKYIPQVIELLEKAEKEGI
                     RVSFDQYPYAAGSTMLGVVLPPWAHSGGTDKLIERLSDENERAKMKKDIANGIEGWDN
                     FIEFAGIDQIFVTSVKTEKNKDTIGKSLLEIGKMRGKDPLDATFDLLKEEENAVGMVD
                     FYGLEEHIIGFMKRDEQNVCTDGLLAGKPHPRAYGSFPKILGRYVRELNVLTIEEAVY
                     KMTKKAARSFSIKDRGELKEGYFADIVIFDKDTVSGCDDFINSMQYPTGIDYVIINGN
                     CVVEEGKYNKIKAGKVLKN"
     gene            1948..3276
                     /gene="ssnA"
                     /locus_tag="PC494_003096"
     CDS             1948..3276
                     /gene="ssnA"
                     /locus_tag="PC494_003096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative aminohydrolase SsnA"
                     /protein_id="HDF3913575.1"
                     /translation="MILVGNGRLISQDSLNPYMEDGCVVINDNLIEDIGTTEEMKVKY
                     PVHEFIDAGKKIIMPGLINSHMHIYSSFARGMAVPGKPSENFLEILNNLWWRLDKQLT
                     LEDTKYSAYATYIECIKNGVTTVYDHHASPNAIEGSLFTISDVAKDLGIRTCLCYEVS
                     DRDGGNTIQQGINENVNFIKYAQKDDTDMIKGMFGLHAAFTLSDDTLNKCASEMAGLD
                     TGYHVHVAEGLADLQYNVDKYGKRVLERFNDFGVLKEKTIAVHCIYISAEEISLLNKT
                     NTFVVHNPESNMGNAVGCSPAIELLKRGVTVGLGTDGYTSDMFESLKVANIIHKHHLK
                     DPRVGFEESQTMLFDNNRKIAKAYYKNDLGVLKKGAYADVIVVDYIPHTPLTENTIGG
                     HTIFGMSGRSVDTTIINGKVLMKDRKLINIDEESILAKSRELSQNLWNRI"
     gene            3421..4773
                     /locus_tag="PC494_003097"
     CDS             3421..4773
                     /locus_tag="PC494_003097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HDF3913576.1"
                     /translation="MSRDKSPKIAPVDERLPVSKSWVFSLQHVLAMCAGAVAVPMMIG
                     SAARLDHASIVFLINACLFMAGIGTLIQSVGIGNIVGAKIPVIEGTSFAAVAGMTAIA
                     SSYSDSQVAIQTVFGSVIVAGLFCILLAPVFEKLIRFFPSVVTGTVVMVIGISLFPVG
                     IKWITDNKLEAVEPNSLALALAVLAITLLSFKFLKGIWNSTAILVGIVLGTLLSMAVG
                     MADFSAVNGVGWLNLNVPLKFGMPRFEPSAILSLCLIMLVLMTESVGNMIAIHEMVDK
                     EVTGKNIKRGLFGDGISTALSGIFNSFPITPFGQNTGIVGLTGIKSRFIAVYAGVILL
                     VLGFLPKFAAIIGAIPKPVLGGVGFAMFGMVMVGGVKTLSKVKFDGTKNGVIVAVSVG
                     LSMIPLTNPDFYHNFPTWVQTIFHSGITTGSLSAVLLNIFFNELGSKKEKNNKVEEAK
                     "
     gene            4965..6074
                     /locus_tag="PC494_003098"
     CDS             4965..6074
                     /locus_tag="PC494_003098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HDF3913577.1"
                     /translation="MANLKVNLYGMEFLNPIMTAAGPGAKDGALCQEAAKGGAGAICT
                     KTISVLPADVPRPCMAKTNSGFLNTELWSELPKEQWIEEEYKKVKETGLPVIVSMGYS
                     AEQIAEVAPLVKPYADAVELSTHYVGTDVAPIVNALKAAKAVLDVPVFMKMSPHTDIQ
                     TIAKAVEEAGADGLVMINSFGPCMAIDVNTGYPIMGSKAGYGWLSGAPIRPLAIRCIY
                     EASQVVNIPIIGVGGITCGKDVAEMLMAGASAVQVCTEAILKGPSIYGKIAKELNEFL
                     DENGYADVNEIKGLTHKKMAARGFRTHSVAPVVDDNKCIKCKQCVTSCVYEALEVTDK
                     LNIDADKCFGCGLCVTRCPKGALSICYNQVEAMNE"
     gene            6357..7748
                     /gene="hydA"
                     /locus_tag="PC494_003099"
     CDS             6357..7748
                     /gene="hydA"
                     /locus_tag="PC494_003099"
                     /EC_number="3.5.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropyrimidinase"
                     /protein_id="HDF3913578.1"
                     /translation="MGIVLKGGKVVTSEKTYCADVRIEDEKIVDIGLDISKENDEIVD
                     VSDSYVIPGGIDTHTHFDLDTGVTKTADNFETGTKAAIVGGTTTILDFATQAKGCSLK
                     DGLEEWHEKAKDKSYSDYGFHMAITDWNDSVCNEMEDMVKEGVSSFKLYMAYKGSLQV
                     DDGVIFEALRKAEEIGGIIGFHCENGDIICELVDKAKSENNLSPKYHQLTRPAIMEAE
                     ATSRLMKIAEVANSKVYVVHLSCKESLEEVLKAKQRGVDVIVETCPQYLLLNDELYDL
                     DGFESAKYVMSPPLRNKENNEILWNAILDNQIDTIGTDHCSFNYKGQKELGINDFSKI
                     PNGSPGVEHRMSLLYTYGVCKNKISINKMVEVTSTNPAKLFGMYPNKGTIEIGSDADI
                     LVLNPNKKSKIEAKKQLQNVDYTPYEGYEVDCQIEHVYLRGKEVVRDGELICNTPSGR
                     YINRRLTKGAREW"
     gene            7742..10303
                     /gene="xdh"
                     /locus_tag="PC494_003100"
     CDS             7742..10303
                     /gene="xdh"
                     /locus_tag="PC494_003100"
                     /EC_number="1.17.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="selenium-dependent xanthine dehydrogenase"
                     /protein_id="HDF3913579.1"
                     /translation="MVEFILNGEKVVAKEGKKLLDFLREDMNITSVKNGCSEGACGTC
                     MVIIDGKATKACVFKTDKLAGKNITTIEGLSERERDVFAYSFASQGAVQCGFCIPGMV
                     ISSKALIDVNNNPTEDDIKKALKGNICRCTGYVKIIKAVDLAAKIFRENIDVPKVNCK
                     GLVGENLPRVDAVGKALGYSEYVDDMRIEGMIYGSAVRSKYPRALVKKIDIEEAKAYP
                     GVVAVLTAKDIPGTIKVGHLKKDWDTLIPEGEITRYLGDGIVLVAAETREALEEAKKL
                     VKIDYEELTPLSTTADALREDAPKIHETGNILVKEHLVRGNAKEKIENSKYVVTKRYT
                     TPATEHAFLEPECAVAGPYEDDGVIIYSTDQGVFATQHECADMLGLPYEKVRVINKMV
                     GGGFGGKEDMSVQHHAALLAYHTKRFVKVQLTRKESIIVHPKRHATEMEFTTACDENG
                     YLTGMKATIISDTGAYASLGGPVLQRLCTHAAGPYNYQDIDITGTAVYTNNPPGGAFR
                     GFGVTQSCFATECNLNLLAEMVGISPWEIRYKNAIRPGQVLPNGQFADEGTAMAETLE
                     AVKEEYEKHPRAGIACAMKNSGVGVGIPDVGRCRLVIKDGKVHIRTSASCIGQGLGTV
                     MTQVVCETANLLPENIVHEVPDTHLTPDSGNTTASRQTVFTGEATKVASNKLKEALDS
                     GKTLLDLEGEEFYGEYESITDKMGCDKENPVSHVAYGYATQVVILDENGKLEKVVAAH
                     DVGRAINPISLEGQIEGGVVMGLGYALTEDYPVVNSVPTAKFGTLGLFKSTDIPEIQA
                     LIVEKNKDLLAYGAKGVGEICTVPTAPAVQNAYYVFDKEFRTELPLQNTPYSKKK"
     gene            10455..11801
                     /gene="rpoN"
                     /locus_tag="PC494_003101"
     CDS             10455..11801
                     /gene="rpoN"
                     /locus_tag="PC494_003101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase factor sigma-54"
                     /protein_id="HDF3913580.1"
                     /translation="MNFNNSLELTQSQKLIMTTQLKQSLSILNMSKLELEEEIKREAE
                     NNPLVEVEKSGEINWEEYIKDMDRSRRLDRTEISYNPDNEVNLENLVKYSSNLYEDLK
                     FQISLYKLTDKELEVCEYIIDSLDEDGYLRTEEKVIVDTLKIDEELFEKCLISVQQLE
                     PSGVGARSLSECLMIQMASLGIYNEILEEIVTKDLNLIANNKYKEISKKYNMSLQKCV
                     ELINIIKTLDPKPGRTCSVEKSVYIQPDVTVEKIDDEFIVYLNEKDSYQIRINSYYKD
                     ILKNSQSDESAKEFIKERLNSATGLMKNIESRKTTVLKIAEEIVKAQDEFLRKGTKYI
                     KPLKMKDIAEKLEFHESTISRGVNGKYMLTPFGVYEFRYFFSSAIETENNEMASSTSI
                     KKIIKETIKDENKKKPLSDDHISKLLKEKGINVARRTVAKYREELGIPSSSKRKEY"
BASE COUNT         4933 a         1419 c         2485 g         3481 t
ORIGIN      
        1 gttgaaaaag ctgattgcta tacaggaaat actatagaaa gtgaaagatt cttcccaggt
       61 tggttatatg atgaagaaga tgaatttgtt caagcagcgt ataagggatt aaaagaagct
      121 ggaatagatt cagaaataac tcaatactca ttctgtacga atggaagtca ctacgcaggt
      181 gaggctggaa taagaactat aggatttggt ccttctaagg aaaatcttgc tcatacaata
      241 gatgagtata tagaattaga ccaattattc aaaggtacag aaggatatta tggtatatta
      301 aaatcagttt ataaaaaata attaggagat ggttttgtga gaactttaat aaaacatgga
      361 cttatagtag atggaaataa aacaccagca tatgaaggag atattttaat agaaaacgag
      421 aaaatattaa aaatatcaca agatttaaac gaagaagctg acaaagttat agatgcaaaa
      481 ggtagagtta tatgtccagg tttcatagat actcatagcc attcagacct agttatttta
      541 gttaatccat ataatgaggt aaagattaga cagggaatta caacagaagt gttgggccaa
      601 gatggtatat ctatggcccc tctacctcaa gagcatatat cttcttggag aaaaaattta
      661 gcaggtttag atggtgaaag tgatgaaatt gattggaaat atgaaacaac agagaattat
      721 ttaaaaatga tggattacaa tggggtaggt ttaaatgaaa cttatttagt acctcatgga
      781 aacgttagaa tggaagctat gggacttgaa gatagacctg ctactaaaga agaaattcaa
      841 aaaatgtgtg aaatcacaga gagagaatta aaagcaggag ctataggatt gtctactgga
      901 cttatatata taccttgtgc atactcattg actgaagaaa ttatagagat gtgtaaggta
      961 gtagcaaaat atgacggagt atttgtagtt caccaaagaa gtgaagcaga tacaatttta
     1021 acttcaatgg aagaaatcat agaaattgga aaacaatcag gagtaaaagt tcatttttca
     1081 cattttaagg tttgtggtaa agcaaactgg aagtatatac cacaagttat agagctttta
     1141 gaaaaagcag aaaaggaagg aataagagta tcttttgacc aatatccata tgcagcagga
     1201 agtacaatgc ttggagtagt tttacctcct tgggcacatt ctggaggaac tgataagtta
     1261 atagaaagat taagtgatga aaacgaaaga gcaaaaatga aaaaagatat agcaaatgga
     1321 atagaaggct gggataattt tatagaattt gctggaatag accaaatatt tgtaacaagc
     1381 gtaaaaacag aaaagaataa agatacaatt ggtaagagct tattagaaat tggaaaaatg
     1441 agaggaaaag acccattaga tgcaacgttt gatttattaa aagaagaaga aaatgcagtt
     1501 gggatggtag atttctatgg attagaagaa catataatag gattcatgaa aagagacgag
     1561 caaaatgtgt gtacagatgg tcttttagca ggtaaaccac atccaagagc ttatggttct
     1621 ttccctaaaa tactaggaag atatgttaga gagttgaatg tgttaacaat cgaagaagct
     1681 gtttataaaa tgactaaaaa ggcagctaga agctttagta taaaagatag aggcgaatta
     1741 aaagaaggat attttgcaga tatagttata tttgacaagg atacagttag tggttgtgat
     1801 gattttatca actctatgca gtaccctaca ggtatagatt acgtaattat aaatggaaat
     1861 tgtgttgttg aggaaggaaa atacaataaa attaaagcag gaaaagtact taaaaattaa
     1921 atcttagctt taaggaggaa taaatttatg attttagtgg ggaatgggag gctaataagc
     1981 caagattctt taaatcccta tatggaagat ggatgtgtag taataaatga taatctaatt
     2041 gaagatatag gtactacaga agaaatgaaa gttaaatatc cagtacatga atttatagat
     2101 gcaggcaaga aaataatcat gccaggtcta ataaattcac atatgcatat atacagctca
     2161 tttgctagag gaatggcagt tccaggaaaa ccttctgaga actttttaga gatactaaac
     2221 aatttatggt ggagacttga caaacagctt acactggaag atacaaaata cagtgcatat
     2281 gcaacgtata tagaatgtat aaaaaatggt gtaacaacag tttatgacca tcatgcaagt
     2341 ccaaatgcaa ttgaaggcag tttgtttaca atatcagatg ttgcaaagga tttgggaatt
     2401 agaacgtgtc tttgttatga agtgtctgat agagatggtg gaaatacaat ccaacaaggt
     2461 atcaatgaaa acgtaaactt tataaaatac gctcaaaaag atgatacaga catgataaaa
     2521 ggaatgtttg ggcttcatgc tgcatttaca ctatctgatg atacattaaa taaatgtgct
     2581 tcagagatgg ctggtcttga tacaggttac catgtacatg ttgctgaagg actagcagac
     2641 ttacaatata atgtagataa atatggaaaa agggttttag aaagattcaa tgattttgga
     2701 gtactaaaag aaaaaacaat agcagttcat tgtatatata taagtgcaga agaaatcagt
     2761 cttttaaata aaacaaatac atttgtagtt cataatccag aatctaatat gggaaatgca
     2821 gttggatgtt ctcctgcaat agagttatta aaaaggggag ttacagtagg attaggaact
     2881 gatggatata ctagcgatat gtttgaatca ttaaaagttg ccaatataat tcacaaacat
     2941 cacttaaaag acccaagagt tggatttgaa gaatcacaaa caatgttatt tgataacaat
     3001 agaaaaatag ctaaagctta ttataaaaat gacctaggag tacttaaaaa aggtgcttat
     3061 gcagatgtta tagtagttga ttatatacca catactccat tgacagaaaa tacaataggg
     3121 ggacacacta tttttggaat gagtggaaga agcgtagata caactattat aaatggaaaa
     3181 gtacttatga aagatagaaa gttaataaac atagatgaag aaagtattct agcaaaaagt
     3241 agagaattaa gtcaaaatct atggaataga atttaaataa ttgatattaa tatacaagta
     3301 agaaacaaga atttagatgt taaaaacaga gcttaaacaa aaataggaat ttaaatgaag
     3361 tatataaata aaaaatatac ggaatagaat attaaattaa atatagaagg gagacccaaa
     3421 atgtctcgag ataaaagccc taaaatagct ccagtagatg aaaggttacc tgtatccaaa
     3481 tcttgggtat tttcactaca gcacgtttta gcaatgtgtg caggagcagt agcagttcct
     3541 atgatgatag gaagtgctgc acgactagat catgctagta ttgttttttt aataaatgct
     3601 tgcttgttta tggcaggtat aggaacactc atacaaagtg ttggtatagg aaatattgta
     3661 ggtgctaaaa taccagtaat agaaggaact agttttgccg ctgtggcagg tatgacagca
     3721 atagcctcat catatagtga ttcacaagtt gcaatacaga cagtatttgg ctctgtaata
     3781 gtagctggat tgttttgtat attacttgct ccagtatttg aaaaattaat aagatttttc
     3841 cctagtgtag ttactggaac agttgttatg gtaataggta tttcactatt tccagttggg
     3901 ataaaatgga taactgacaa caaattagaa gcggttgaac caaactcatt agcattagct
     3961 ttagcagtat tggcaataac tttactttca tttaaattct taaaaggaat ttggaatagc
     4021 acagctatat tggtaggtat agtacttggt acactacttt ccatggcagt tggaatggca
     4081 gattttagtg cagtaaatgg agttggttgg cttaacttaa atgtaccttt aaaatttgga
     4141 atgcctagat ttgaaccatc tgcaatacta tcattgtgtt tgattatgtt ggtacttatg
     4201 acggaatcag ttggtaatat gatagctatt catgaaatgg tagacaaaga agtaacaggt
     4261 aaaaatatta aaagaggtct atttggagat ggaatatcta cagcattatc tggaatattc
     4321 aattcatttc caataactcc atttggtcaa aatacaggaa tagtaggtct tacaggtata
     4381 aaatcaagat ttatagcagt ttacgcaggg gttatattgc tagtacttgg attcttacca
     4441 aaatttgcag caataatagg agcaatacct aagcctgttc ttggaggcgt aggattcgca
     4501 atgtttggaa tggtaatggt tggaggagta aaaactttaa gcaaagtaaa atttgatgga
     4561 actaaaaatg gggttatagt agcagttagt gttggtttgt ctatgatacc actaacaaat
     4621 cctgatttct atcataattt cccaacttgg gtacaaacaa tattccatag tggaataaca
     4681 acaggtagtt tatcagcagt gcttttaaac atattcttca atgaactagg ttctaaaaaa
     4741 gaaaaaaata ataaagttga agaagcaaaa taaaaataaa acaagtaaaa atctatattg
     4801 acttaaagtc attaagtatt aataaaaata attcagagat attaataatt caacaaaact
     4861 atcttatatt ttaaataata taaaaaagta aataaataac gaatacaaat aaaagaatac
     4921 aatctaaata ttaaaaatat ttaatttaag ggagagataa taatatggct aatttaaaag
     4981 ttaatttata tggaatggaa tttttaaacc caattatgac agcggcagga cctggagcaa
     5041 aagatggtgc tctctgtcaa gaggcagcaa aaggtggagc aggagctata tgtacaaaaa
     5101 ctatatctgt attaccagct gatgtaccaa gaccatgtat ggcaaaaact aatagtggtt
     5161 ttttaaacac agaattatgg tcagagcttc caaaagagca atggatagag gaagaataca
     5221 aaaaggtaaa agaaacaggg cttccagtaa tagtaagtat gggatattca gcagagcaaa
     5281 tagctgaggt tgctccttta gtaaagcctt atgcagatgc agttgaatta tctactcatt
     5341 atgtaggtac agacgttgca ccaatagtaa atgctttaaa agctgcaaaa gctgttttag
     5401 atgtaccagt atttatgaaa atgagtcctc atactgacat tcaaactatt gcaaaagctg
     5461 ttgaagaagc aggtgcagat ggacttgtaa tgataaactc atttggacca tgtatggcaa
     5521 tagatgtaaa tacaggatac cctataatgg gaagtaaagc tggatacgga tggttatcag
     5581 gtgcaccaat aagacctcta gcaataagat gtatatatga agcttctcaa gttgtaaata
     5641 taccaataat cggtgttggt ggaatcactt gtggaaaaga cgtggctgaa atgttgatgg
     5701 ctggagcaag tgctgttcaa gtatgtacag aagcaatcct taaagggcct tctatctatg
     5761 gaaaaattgc taaagaatta aatgaatttt tagatgagaa tggatatgct gatgttaatg
     5821 aaataaaagg attaactcat aagaaaatgg cagctagagg gtttagaact cattcagtag
     5881 ctccagtagt ggatgataac aagtgtatca aatgtaagca atgtgtaaca agctgtgtat
     5941 acgaagcttt agaagttaca gataagttga acatagatgc agacaagtgt tttggatgtg
     6001 gattatgtgt aactagatgt ccaaaaggag ctttaagcat ctgctacaat caagtagaag
     6061 ctatgaatga gtaataatta tatagaattt tggtaattaa cttagagtaa taggtattag
     6121 gataataaaa tatatcagat aaacaaacac atattatgca ttaataatac agtctaaagt
     6181 taataatttt attatattga tttaactaaa tattagttta gctgaatatt aatttaatta
     6241 ggtattggtt taatcttaat atagatttac tacgtataag tgaactaact agattacttt
     6301 aagttaattt tttcatataa aataaattga tacattacaa gtaaggtgga gtctatatgg
     6361 gaattgtttt aaaaggtggg aaagtagtaa caagtgaaaa aacttactgt gcagatgtaa
     6421 gaatagaaga tgaaaaaata gtcgatatag gtcttgatat atcaaaagaa aatgatgaaa
     6481 tagttgatgt tagtgattct tatgttatac caggaggtat agatacacac acacactttg
     6541 acttagatac aggcgttact aagacagcag ataactttga gacaggaaca aaagctgcta
     6601 tagtaggagg aactactact atattggatt ttgctacaca agctaaagga tgttctttga
     6661 aagacggatt agaagaatgg catgaaaaag ctaaggataa atcctattca gattatggct
     6721 ttcatatggc tataacagat tggaatgact cggtttgtaa tgaaatggag gatatggtga
     6781 aagagggagt atcttcattt aaactgtata tggcgtataa aggaagcctt caagttgatg
     6841 atggtgtaat ctttgaagca ttgagaaaag cagaagagat aggaggaatt attggtttcc
     6901 attgtgaaaa tggggacata atatgtgaac ttgtggataa agcaaagtca gaaaataatt
     6961 tatctccaaa atatcatcaa ttaactagac cagctataat ggaggcagaa gctacatcaa
     7021 gacttatgaa gatagctgaa gttgcaaatt ctaaagtata tgtagttcac ttaagctgta
     7081 aagaatcctt agaggaggtt ttaaaagcta agcaaagagg tgtggatgta atagttgaaa
     7141 cttgtcctca ataccttcta ttaaatgatg aattatatga tttagatgga tttgaaagtg
     7201 ctaagtatgt aatgtcacca cctttaagaa ataaagaaaa taatgaaata ttatggaatg
     7261 ctattttaga taatcaaata gacactatag gaacagacca ttgttctttt aattataagg
     7321 gacagaagga acttgggata aacgatttca gcaagatacc aaatggttct ccaggtgtag
     7381 aacataggat gagtctttta tacacatatg gagtctgtaa aaataaaata tctatcaaca
     7441 agatggtaga agtaacatca actaatccag caaagttgtt tggaatgtat cctaataaag
     7501 gaactataga aataggcagt gatgcagata tattagtctt aaatccaaac aaaaaatcca
     7561 aaatagaagc aaaaaaacaa ttacaaaatg tagattatac accttatgaa gggtatgaag
     7621 tggattgtca aatagaacat gtttatttaa gaggaaaaga agtagttaga gatggagaat
     7681 taatttgtaa tactccaagt gggagatata taaataggcg tctaacaaag ggggctagag
     7741 aatggtagaa tttatattaa atggagagaa agttgttgca aaagaaggca aaaaactttt
     7801 agacttcctt agagaagata tgaatataac ttcagttaaa aatggatgtt cagaaggtgc
     7861 ttgtggaaca tgtatggtta taatagatgg taaagctact aaagcatgtg tatttaaaac
     7921 tgataaatta gctgggaaaa acataacaac tatagaggga ttatcagaga gagaaagaga
     7981 tgtttttgca tattcttttg ctagtcaagg agctgtacaa tgtggatttt gtattccagg
     8041 tatggtaatt agttcaaaag cacttataga cgttaataat aatcctactg aagatgatat
     8101 aaagaaagct ttaaaaggca atatatgtag atgtacaggg tatgtaaaaa taattaaagc
     8161 tgtcgattta gcggcaaaga tttttagaga aaatatagat gtgccaaaag taaactgtaa
     8221 gggtttagta ggtgaaaatc ttcctagagt tgatgcagtt ggcaaagcac ttggatattc
     8281 tgaatatgta gatgatatga gaattgaggg tatgatttat ggttcagcag ttagatctaa
     8341 gtatcctaga gctttagtta aaaaaataga tatagaagaa gcaaaagctt atccaggagt
     8401 tgttgcagtt ctaacagcta aagatattcc aggaactata aaggtaggac acttaaagaa
     8461 ggattgggat actttaatac cagaaggtga aataactaga tacttaggag atggaatagt
     8521 tttagtagca gcagaaacta gagaagcgtt agaagaggcc aaaaagctag ttaagataga
     8581 ttatgaggaa ttaacaccat taagtactac agcagatgca cttagagaag atgctccaaa
     8641 gatacatgag acagggaata tacttgttaa ggaacattta gtaagaggaa acgctaaaga
     8701 aaagatagaa aattcaaaat atgttgtaac taaaagatat actacacctg ctacagaaca
     8761 cgcattttta gagcctgaat gtgcagtagc tggtccttat gaagatgatg gagtaataat
     8821 ctattcaaca gaccaagggg tgtttgccac tcaacatgaa tgtgcagata tgttaggatt
     8881 accatatgag aaggtaagag ttataaacaa aatggtagga ggagggtttg gtggaaaaga
     8941 agacatgagt gttcaacacc atgcagcctt acttgcatac catacaaaga gatttgtaaa
     9001 agtacagtta acaagaaaag aaagtattat tgttcatcca aaacgacatg ccacagaaat
     9061 ggaatttacg acagcatgtg atgaaaatgg atacttaacg ggtatgaagg caacgataat
     9121 atctgacaca ggtgcatatg cctctcttgg aggaccagtg ctacaaagac tgtgtactca
     9181 tgcagcagga ccatacaatt atcaagatat tgatataaca ggaacagcag tatatactaa
     9241 taaccctcct ggaggagcat ttagaggatt tggagttaca cagagttgtt ttgcaactga
     9301 atgtaatcta aatttacttg ctgaaatggt tggaatatct ccttgggaga taagatataa
     9361 aaatgcaata agacctgggc aagttttacc aaatggtcaa tttgcagatg aaggaacagc
     9421 aatggcagag acactagaag ctgtaaaaga agagtatgaa aagcatccac gtgcaggtat
     9481 agcttgtgct atgaaaaata gtggggttgg agttggtata cctgatgttg gaagatgtag
     9541 attggtgata aaagatggca aagttcacat aagaacaagt gcttcttgta taggtcaagg
     9601 gcttggtact gttatgactc aagtagtttg tgaaactgct aacctacttc ctgaaaatat
     9661 agttcatgaa gttccagata ctcatttaac accagactct ggtaatacta cggcttcaag
     9721 acagacagta tttacgggag aagctactaa ggttgcatca aataagttaa aagaagcttt
     9781 agactctggc aaaactttac ttgatttaga gggagaagag ttttatggag aatatgaaag
     9841 tattacagat aaaatgggtt gtgacaaaga aaatccagta agtcatgttg cttatggata
     9901 tgcaacacaa gttgtaattc tggatgaaaa tggaaaacta gaaaaagtag tagcagcaca
     9961 tgatgttgga agagctataa atccaatcag tttagaaggt caaatagaag gtggagtagt
    10021 tatgggtctt ggatatgctc taaccgaaga ttacccagta gtcaactctg ttcctacagc
    10081 taagtttggt acattaggtt tatttaaatc tacagatata ccagaaatac aagctttaat
    10141 agttgaaaag aacaaagatt tattggctta tggggcaaaa ggtgtaggag aaatttgtac
    10201 agttcctact gcaccagcag tacaaaatgc ctattatgta tttgataaag aatttagaac
    10261 tgagttacca ctacaaaata ctccatatag taaaaaaaag taacaaaaaa aagaaatatt
    10321 aaataaaaaa atagatgaaa ttgtaaataa aaaaaaccct tttgcataag gtatatttta
    10381 aatgatagaa tatacatata caggagggtt tttcttttat aaaataagtt taataaaatt
    10441 gagaggtgag cagaatgaat tttaataata gtctagaatt aactcagtct cagaagctaa
    10501 taatgactac acaacttaag caatcattat caatattaaa tatgagtaag ttagagttag
    10561 aagaagagat aaaaagagaa gcagagaata acccattagt tgaagtcgag aaaagtgggg
    10621 agataaattg ggaagagtat ataaaagaca tggataggtc aagacgttta gatagaacag
    10681 agataagcta taatcctgat aatgaagtta atctagaaaa tttagttaaa tattcgtcaa
    10741 atttatatga agatttaaaa tttcagataa gcctgtataa acttacagac aaagaattgg
    10801 aagtctgtga gtatataatt gatagtttag atgaggatgg atatttaaga actgaggaaa
    10861 aagtaattgt tgatacctta aagatagatg aagaactttt tgaaaaatgt ttaattagtg
    10921 ttcagcagtt ggaacctagt ggagtagggg caagaagtct ttcagaatgt ctgatgatac
    10981 aaatggctag tttaggaata tataatgaaa ttttagagga aatcgttaca aaagacttaa
    11041 atttaattgc aaataataaa tataaagaga taagtaaaaa gtacaatatg tcattacaaa
    11101 aatgtgttga actaataaac ataattaaga cattagaccc caaaccagga agaacttgtt
    11161 cagtagagaa aagtgtatac attcaacctg atgtaacagt agaaaaaatt gatgatgaat
    11221 ttattgtata tttaaatgag aaagattctt atcaaataag aatcaatagt tattataaag
    11281 acatattaaa aaattcacag tctgatgaaa gtgcaaaaga atttataaaa gaaagactaa
    11341 attcagcaac aggacttatg aaaaatatag agagtaggaa aactacagta cttaagattg
    11401 cagaagagat agtaaaagct caagatgaat ttttgagaaa agggacaaaa tatataaaac
    11461 ctttgaaaat gaaagacata gcagaaaaat tagaatttca tgaatctact ataagtagag
    11521 gtgtaaatgg taaatatatg ctaacacctt ttggcgtata tgaatttagg tactttttca
    11581 gtagcgccat tgagactgag aataatgaaa tggcatctag tacaagcata aaaaaaatta
    11641 taaaggaaac aataaaagac gaaaataaaa agaaaccttt aagtgatgac catatatcta
    11701 agttactaaa agaaaaagga atcaatgttg caagaaggac agttgccaaa tatcgtgaag
    11761 aattaggaat cccatcttca agtaagagaa aagaatacta ataagtaaaa gacaaatatc
    11821 agtatggtaa ggggaaaagg ctaattaaga gatgaatgta gattgggcta aaaattttat
    11881 aaagtaaaat aatataatat gaaaaagtat taaaatgcta taaggtatta aaaaactggg
    11941 gaacattaaa acattaagat agcaaagaac ataaaaaact aaagaagatt aaaacattaa
    12001 agaacattag agctttgagg aatattagaa ctttaaagaa tattaaaatt tataaaatat
    12061 aaaaatacta aaaagaattg aaaaactggg gaacattaaa atattgtaaa atgctaaaaa
    12121 actagaaaac ataattaaat aagtgcttat aaagaatgat taaattaaat aagtgtttgt
    12181 aaagaataat tagatattag aaaaagaaga atacctagat aaataaacta ttattaaatt
    12241 taataatcac aaaaggaaaa cacgtagggt ataaataaaa atcttaacta gataaaagta
    12301 aacttagttg tagataaa
//
LOCUS       DAMKNB010000097        12255 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.103, whole genome shotgun sequence.
ACCESSION   DAMKNB010000097 DAMKNB010000000
VERSION     DAMKNB010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 12255)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12255)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12255
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.103"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            240..422
                     /locus_tag="PC494_003102"
     CDS             240..422
                     /locus_tag="PC494_003102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3913581.1"
                     /translation="MFKDKIDECVHIMTAYIASLKEYYSFIETQIGDFIKKYGEDVVE
                     LCLHRVMILLCECGLA"
     gene            1254..2168
                     /locus_tag="PC494_003103"
     CDS             1254..2168
                     /locus_tag="PC494_003103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2935 domain-containing protein"
                     /protein_id="HDF3913582.1"
                     /translation="MIDNQKYVILSLELHLFFSRIMKEHALFLEAGFTNKNYNLAMEA
                     DHYKKQFEDLLSYTVSASNGIIRPDILYSEELVTTLTSVAEQKTEEFTGIEINKNITT
                     RELNLQSGVNPQVGQDLVNYVAQLNSDAIRLLDGLINFKERVLDGVLSCTIFTSNYPL
                     LLEHIIHEANLYRSYVVDLENKIDIESKNAKEIELFWDHIMMEHALFMRGLLDPSEGE
                     LINTSNDFAIKFNELIEKTNEMTDSNIKNITEETLNETVEFKDFKEAGASGIEQCKIK
                     SIILPLLADHVLREANHYIRILESYKNM"
     gene            2558..3205
                     /locus_tag="PC494_003104"
     CDS             2558..3205
                     /locus_tag="PC494_003104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate utilization protein"
                     /protein_id="HDF3913583.1"
                     /translation="MIRQTPLEKRYDKLGPHIVTALKKRYFDAYYCKTRNEALQQILD
                     LIPQNHVVSWGGSETLKEMGVQTAVREKGFKVIDRDLAKTPEERTEIMRQALLCDTFL
                     MSSNAISEDGQLFNIDGNGNRVAAMIFGPKNVIVVAGMNKIVKNIDDAIQRTRTIASP
                     AVVQRFQDVNTPCYINGSCIDCTSPESICAYMVTTRISRPAKKIKVILVGENLGL"
     gene            complement(3372..3941)
                     /locus_tag="PC494_003105"
     CDS             complement(3372..3941)
                     /locus_tag="PC494_003105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HDF3913584.1"
                     /translation="MKKFIICIIMFAISVLVLAGCTNDNKIKNEVDSMFNSIKTQDAD
                     TVDKYFPKSGLGNLIYEDKEGFKMYSKNMTWEISDIKNNKDKVTVDLKINNTDMVSIL
                     KKNPPKLGEMMPNPTMKDIDSAKKKEFNITLELVKSGDNYVCKVNQESAMKLLNVITG
                     GGIDYLADYNKDYYKQLDEEQKNYENKNS"
     gene            complement(3946..4845)
                     /locus_tag="PC494_003106"
     CDS             complement(3946..4845)
                     /locus_tag="PC494_003106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HDF3913585.1"
                     /translation="MKLLSKVNNNIRLITQVAFTALTNGYVNGFLEGTIYGGESKKLC
                     VPGLNCYSCPGALGACPIGSLQAVLSSREYKFSFYVVGFLMAFGAFFGRFVCGWLCPF
                     GLVQDLLHKVPFPVKIKKVYGDKYLKYLKYIVLIMFVIILPVAIVNVAGGGNPWFCKW
                     ICPSGTLLGGIPLILGNENLRESIGFLFSWKLSILLLILLMSIITYRPFCKYICPLGA
                     IYGFFNPISIYRFKIDKDKCTNCTACQTKCKLDIPIYKDVNSPDCIRCGECIKVCPQN
                     AITTTFSKDKKENNICAKKYRGI"
     gene            complement(4856..5005)
                     /locus_tag="PC494_003107"
     CDS             complement(4856..5005)
                     /locus_tag="PC494_003107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3913586.1"
                     /translation="MSNFIKDNKKSISIIAISIIFIALGTYRGETNTVLTKAIMICLE
                     CIGIG"
     gene            complement(4998..5582)
                     /locus_tag="PC494_003108"
     CDS             complement(4998..5582)
                     /locus_tag="PC494_003108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlpA family protein disulfide reductase"
                     /protein_id="HDF3913587.1"
                     /translation="MKRFFIVVLGCICVLGMISGCSKKESKPVEKNKNNSEWFSNLDT
                     EDVDGNKVTKEIFSNKELTLINVWTTWCGPCVGEMPELEALSKEYESNNSNVAIKGLV
                     VEVDKTDMRTGLSNEEKNLVKDIMKKSDATYQQLTVSEELKKTDFKRVMEFPTTYFVD
                     KKGNFVGEKVVGANSKEDWKKIIDERLKMVKANE"
     gene            5971..7296
                     /gene="cdeA"
                     /locus_tag="PC494_003109"
     CDS             5971..7296
                     /gene="cdeA"
                     /locus_tag="PC494_003109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MATE transporter CdeA"
                     /protein_id="HDF3913588.1"
                     /translation="MENLFTRKFTTFEFLKFVSPAIISMIFISLYTIIDGIFVSTLVG
                     SDALASINIVLPIINLVCGFGIMMATGGGAIVSIRMGENRQDEANSTFSFIVLFSLIV
                     GILFTVISYFFIKEISILLGATDKLLPYCITYGKVMILCTPFYILKFIFEYFARTDGN
                     SKFSLFLSVIGGVTNIILDYVFIKYFGMGLLGAAVATAIGIILTCVLGIIYFLSNKST
                     LKLRKPKTDFRLIRDTMINGSSEMVTELSTGITTFLFNVVALKLAGENGLAALTIVLY
                     AHFLMTSVYLGFAAGVSPLISYNFGAENSDKLKETFKHSLKFIFVSSLLVFIIALVFA
                     PFIVRVFVSPDNTVFKLALQGLKIFAFAFLFVGINIFASGFFTAFHNGKISAIISFSR
                     AFVFIIIGIIILPPMLNMTGLWLTVPFAEVITIFISILFIKKYKCRYKY"
     gene            complement(7391..8185)
                     /locus_tag="PC494_003110"
     CDS             complement(7391..8185)
                     /locus_tag="PC494_003110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF3913589.1"
                     /translation="MNELKPYIKFFNKNTKLYIIIFMIVGIVMNILPVFILKIFGEAS
                     KTNLSTIVNPILTYITILLFVYGVNIANKDFSGALSIRADRKSCIKAIVIDLIILSFV
                     ISILGIVLIFLSKLFIEIITGYSIELSVLLKRDMIWTSISALIDPSTSSMPLTYLNYF
                     VQICINEICIGFIGVLLGAFTYRVRKVTSITILIGLPILMIIYIVNFATKNMHKMLLY
                     LEKIIYSFQNPFILFGTKVGIIVICIIFIILLLRKAPIKEYANDLL"
     gene            complement(8186..9061)
                     /locus_tag="PC494_003111"
     CDS             complement(8186..9061)
                     /locus_tag="PC494_003111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF3913590.1"
                     /translation="MSSSIKIENLSHSFKKQNIFNNMSLNFEKNKIYGLLGKNGAGKT
                     TLLNIMVNQLIQNEGEIEILGKNPKEDIKVLEEVCIVREKEFYSPDFKVGQIFEFSSS
                     FYKSYDKGLEEELCKYFDLNTKKKYKQLSRGMKTILSNIIGICSNSAITIFDEPTIGL
                     DAVNRQEFYNIILDSYIKNPRTIIISTHLIDEIDDLLEHVIILNEGKIIIDEEIDVIK
                     QKAHYITGNKEELEKLECIKNIKPKKAFGNAVAYFYYGDFSENDEKILKNSNIDVGYI
                     GLQDMFVNMTKKEEL"
     gene            complement(9065..9433)
                     /locus_tag="PC494_003112"
     CDS             complement(9065..9433)
                     /locus_tag="PC494_003112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDF3913591.1"
                     /translation="MKLVLNNEEPIFIQIARAIEDEILSNGIKEEEQVPSTTELSKLY
                     KINPATVLKGINILVDKNILYKKRGIGMFVSDGAKTIIKEARKENFKHNFVKNLLQEA
                     NKLEINREELVDIIINFKED"
     gene            complement(9616..10275)
                     /gene="deoC"
                     /locus_tag="PC494_003113"
     CDS             complement(9616..10275)
                     /gene="deoC"
                     /locus_tag="PC494_003113"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HDF3913592.1"
                     /translation="MKHILKTVDHTILKATTTWEDIKILCDEAVDMSVASVCIPPSYV
                     KRASEYLKGKIKICTVIGFPLGYQTTATKVFEAKDAIENGADEVDMVVNISDIKNKDY
                     DNIGKEIKEIKKAIGDKVLKVIIETCYLDEDEKIKMCEIVTMSGSDFIKTSTGMGTGG
                     ATLEDIKLMKEHVGKNVKIKAAGGVKSISDAEKFIEAGAERLGTSSICKILKNEDTTD
                     Y"
     gene            complement(10311..11498)
                     /gene="murJ"
                     /locus_tag="PC494_003114"
     CDS             complement(10311..11498)
                     /gene="murJ"
                     /locus_tag="PC494_003114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="murein biosynthesis integral membrane protein
                     MurJ"
                     /protein_id="HDF3913593.1"
                     /translation="MKQEPCDFSHGRFRTGIIFIGITSVMSAFLQIKENFIVVGFGSI
                     PYNIVIIISIMLSTVFGPYILPIGAVVAMVVQLLFYMFFVKKTNYKYLYYLNFKDDSL
                     IKLLALLSPVFIGVAVNQVNSLVDTTLASTLVKGSIPALTYADRLNGFVTGTFTASIV
                     SVMYPMLSKLSAENNQKKFTSSVKSSINMIIISMIPISVASIFFATPVVRIIFERGAF
                     DARATQMTATALIFYAVGMTAFGLRDILGKVFYSLQDTKTPMVNGIISVGVNIVLDLV
                     LIKPMAHGGLALATSSSSIACILLLFLNLKRKVGYFGQDKIIKATLKSVVASLIMGVL
                     SYFTYKFIFGILGVGTFNEFVSLAISVIVGGGIYTLLMTIFKVEEVDMILNIAKRKLH
                     LKK"
     gene            complement(11575..>12255)
                     /locus_tag="PC494_003115"
     CDS             complement(11575..>12255)
                     /locus_tag="PC494_003115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDF3913594.1"
                     /translation="RILNATISKEPSGRYYVSLCCIDVDIEVFENTNNHIGLDLGIKE
                     FCISSCGEFIENPKYLKKSLNKLAKLQRELSRKTIGSLNRNKARLKVARLQEHIANQR
                     NDFLQKLSTKLIKENDIICIEDLQVKNMIRNRKLSRLISDVSWSEFIRQLEYKANWYG
                     RQIVKVGKFFASSQICNKCGYKNEEVKNLNIREWICPSCNETHDRDINASINILKEGL
                     RLITIQNK"
BASE COUNT         4260 a         1883 c         1375 g         4737 t
ORIGIN      
        1 acttatatta atttatatta aatatctact aactcaaata ttcataatta aactttaaac
       61 tggataaatt ttcttttaag aatgaaagtt tatccagttt tgcgattata ataaccagtt
      121 ttacatatcc acttgtaaaa tatatctaag caatatatca tactatatag atttatgagt
      181 gaaataatat ctgctattta ctgaatattt ttatttttcg ttttttaggg ggattagttg
      241 tgtttaaaga taagattgat gaatgtgttc atataatgac tgcatatatt gctagtttaa
      301 aagaatacta ttcattcata gaaactcaaa ttggtgattt tattaaaaaa tatggagaag
      361 atgttgtaga gttatgtctc catagagtga tgattctact atgcgaatgt ggtttggcat
      421 aaaattaaat ttattaaaat gggtaagaag aatcctatat aatattcttc ttacccattt
      481 taatatatca atttcatagc ttatcgttta aaatatttta catccattac tagacaactt
      541 tacattctct ttttaattct agtatattta aatcatttta gttgctcctt atttattctt
      601 attacttgtt ttattttata aataaaataa ttctttttaa taatgttttt tgttgatatt
      661 cctatcacac atccaattat ttatcattgt cttgaaattg tttgcatact taatttaatc
      721 caattgaaac actccagcat agaatcccct gtaaaataga agttggatta aatcctaaca
      781 tctatacaga aaatactact ccaagcacaa gcaatataat ggaatatatt tatcacttaa
      841 ttttttatac tttttaaatc ccatacctaa aacattaagt gcagctatta gaattaataa
      901 ttgttgtggt ataaaattat gcttgcttca tatttattca ttttttccta taaaagttct
      961 tgttttacaa aaaacatttg ttttgtatca aaacaatact tataaattac ataattctca
     1021 taaaaatttc taatattact tgtactctta ataaataata gccaacaagc accttaaatc
     1081 attatatcta tatctaataa gaaacacagt aagataattt tttcgcccat aacttaataa
     1141 aaactgttga tattagtagc aattgaattt agttaattta tttataatat acataaattt
     1201 aaatattacg aataaagtat tataaatagg atactttcta aagggaggaa attatgatag
     1261 ataatcaaaa atatgttatt ttatcactag aattacattt atttttttca agaattatga
     1321 aagagcatgc tcttttttta gaagcaggat tcacaaataa aaattataat cttgctatgg
     1381 aagctgacca ttataaaaag caatttgaag atttattatc atacactgtt agtgctagta
     1441 atggtataat tagacctgat atattatatt cagaagagct tgtaactact ctcacatcag
     1501 ttgcagaaca aaaaacagaa gagtttacag ggatagaaat aaacaaaaac atcactacaa
     1561 gagaattaaa tctacaaagt ggtgtaaacc cacaagttgg tcaagattta gtgaactatg
     1621 tagctcaact taactctgat gcaataagat tacttgatgg gcttattaat tttaaagaaa
     1681 gagtcttaga tggtgtacta tcatgtacta tatttacatc aaactaccct ctacttcttg
     1741 aacatataat acatgaagca aatttatatc gttcttatgt agttgacctt gaaaataaaa
     1801 tagatattga gtcaaaaaac gctaaagaaa tagaattatt ctgggaccat attatgatgg
     1861 aacatgctct gtttatgaga ggattactag acccctcaga aggtgaacta ataaatactt
     1921 caaatgattt tgctataaaa tttaatgaat taattgaaaa aacaaacgaa atgactgatt
     1981 ctaatatcaa gaacattaca gaagaaactc taaatgaaac tgttgagttt aaagatttta
     2041 aagaagcagg agcatcagga atagaacagt gtaagataaa atctataata ttaccacttt
     2101 tagcagacca tgttttaaga gaggcaaatc attatattag aatattggag agttataaaa
     2161 acatgtaatt aaaaattact tttaaaataa tctttgcata tttagataaa ataaaggtac
     2221 agttaactgt acctttattt tttataaact tataaaattt aaacaagtta ttcataaaat
     2281 aaaataataa tcatctataa cccacaactt tattttatat taaataaaaa gtattagtga
     2341 ttatgtttta taggtatttc tttattcagt tatttattaa aaactaatag taaatcttat
     2401 actaatcgca tatttatgtt ataactatat tgtaactatt ttcgtaatct taggaaaagg
     2461 ttacttataa aattaacctt atacaataat atatcgtata atcttaatta gcataatagt
     2521 tacaatatta aaatttaaat atgggagtga ttttagtatg ataagacaaa caccattaga
     2581 gaaacgatat gacaagctag gtcctcatat tgtaacagca ctcaaaaaac gttattttga
     2641 tgcttattac tgtaaaacta gaaatgaagc tttgcaacaa attttagatt taattcctca
     2701 aaatcatgta gtatcatggg gaggatctga aacacttaaa gaaatgggcg tacaaactgc
     2761 tgttagagag aaaggattta aagttattga tagagattta gcaaaaactc cagaagaaag
     2821 aactgaaatt atgcgtcaag cacttctatg cgatactttt ttgatgagta gcaatgcaat
     2881 tagtgaagat ggacaactct ttaatattga tggaaatggc aatcgtgtag ctgcaatgat
     2941 atttggtcca aaaaatgtta tagttgtagc tggtatgaat aaaattgtaa aaaacattga
     3001 tgatgcaata caaagaacta gaacaattgc atctccagca gttgttcagc gttttcaaga
     3061 tgtcaataca ccatgctata ttaatggaag ttgtatagac tgcacaagtc ctgaaagcat
     3121 ttgtgcatac atggttacta caagaatcag tcgtccagca aaaaaaataa aggtaatatt
     3181 ggtaggagaa aatcttggtc tataaaatat acatacatgt aaatagctct ataaataata
     3241 aaatcatatg aaataactta tttctaaaag tggtagaata aaagcttcta caagactttc
     3301 attctaccac ttttatattc ttttaatttg tgtttctata ttattaattg ctccgatttt
     3361 catatatatt actaactatt tttattttca taattttttt gttcttcatc aagctgttta
     3421 taataatctt tattatagtc agctagataa tctataccac ctcctgtaat cacatttaat
     3481 aatttcattg cagattcttg attaacttta caaacataat tatcaccaga tttaacaagc
     3541 tctaatgtaa tattaaattc ttttttcttt gcagaatcaa tatctttcat agttggattt
     3601 ggcatcattt ctcctagttt aggaggattc ttttttaaaa tagaaaccat atcagtattg
     3661 ttaattttta aatctacagt cactttatcc ttattattct ttatatctga aatttcccaa
     3721 gtcatatttt tagaatacat tttaaatcct tctttatctt catatataag attacctaac
     3781 cctgattttg ggaaatactt atcaacagta tctgcatctt gtgtttttat tgaattaaac
     3841 atactatcca cttcattttt tatcttatta tcattagtac aaccagctaa cactagtact
     3901 gatattgcaa acattataat acatataata aatttcttca ttaaattata tccccctata
     3961 cttttttgca caaatattat tctctttttt atcttttgaa aaagttgtag taattgcatt
     4021 ttgtggacaa acttttatac attcaccaca cctaatacag tctggactat ttacatcttt
     4081 atatattggt atatcaagct tacattttgt ttgacatgct gtacaatttg tacatttatc
     4141 tttatcaatt ttaaatctat atattgaaat aggattaaaa aaaccataga ttgctcctaa
     4201 agggcatata tacttgcaaa atggcctata agtaatgatt gacatcaata atatcaatag
     4261 caaaatactt aacttccagc taaataaaaa tcctattgat tctcttaaat tctcatttcc
     4321 taaaataagt ggtattcctc ccaaaagtgt tcctgaaggg caaatccatt tacaaaacca
     4381 aggatttcca ccccctgcta catttacaat agcaactggc aaaataatta caaacattat
     4441 taagactata tactttagat attttagata tttatcacca taaacttttt ttatctttac
     4501 tggaaagggt actttatgta gtaaatcttg tacaagtcca aagggacaaa gccaaccaca
     4561 aacaaatctg ccaaaaaaag caccaaatgc cattaaaaaa ccaacaacat aaaatgagaa
     4621 tttatactct ctgcttgata aaactgcttg taatgaacct attgggcatg ctccaagtgc
     4681 acctggacat gaataacaat tcaatccagg tacacataat tttttacttt ctcctccata
     4741 tatagttcct tctaaaaatc catttacata tccatttgtt aatgctgtaa atgcaacttg
     4801 agtaataagt cttatattat tatttacttt agataataac ttcattcctc ttctcctaac
     4861 caataccaat acactcaaga caaatcataa ttgctttagt taatactgta tttgtttctc
     4921 cacgatatgt acctaatgca ataaatataa tactaattgc aataatagaa atgctttttt
     4981 tattatcttt aataaaatta ctcattggct tttaccattt ttagtctttc atctataatt
     5041 tttttccaat cttccttact atttgcacct acaaccttct cacccacaaa gtttcctttc
     5101 ttgtctacaa aataagttgt tggaaactcc ataactcttt taaaatcagt ttttttaagt
     5161 tcttcagata cagtcaattg ttggtaagtt gcatctgact ttttcataat gtctttaact
     5221 aaatttttct cttcatttga aagaccagtt ctcatatcag ttttatcaac ttctacaact
     5281 aatcccttta tagctacatt ggaattatta ctctcatatt cttttgataa tgcttcaagc
     5341 tctggcattt cacccacaca tggtccacac caagtagtcc agacattaat aagagtaagt
     5401 tctttatttg aaaatatctc ttttgttacc ttatttccat caacatcctc cgtatctaaa
     5461 ttactaaacc attcactatt attcttgttt ttttctactg gcttagattc ttttttgcta
     5521 catccagaaa tcatacctaa aacacaaata catcctaaaa ctactatgaa aaaccttttc
     5581 atatctcaca ctcctagaat ttatatagta tataaaatcg ctgcttgaaa taaaaataac
     5641 ttatcttcta tattaaagta attatattta ataaataaga gctaatttaa aaaaagatat
     5701 acagttaaaa tctatttctt ttcagacaaa atcttatata tatataatag cttgtaaatc
     5761 ttaagattat atacatatat ttctaaagat tttcttaaga aacagttaga ttttactaat
     5821 ataagtttat taattagcac tatactaatt tatcttaata tgattttttg ttgattttaa
     5881 gctgtttatc gtataaataa aatttttctt gactatatag ttactatata gcttattata
     5941 tatagagagt aataaaagga ggtaaaattt atggaaaatt tatttacaag aaaattcact
     6001 acttttgaat ttctaaaatt tgtttctcct gcaattatat ccatgatatt tatatctttg
     6061 tatacaataa tagatggcat ctttgtatcg acattagttg gttctgatgc tcttgctagt
     6121 ataaatattg tactacctat aattaacctt gtttgtggat ttggaataat gatggcaact
     6181 ggtggaggtg ctatcgtttc tatacgtatg ggtgaaaata gacaggatga agccaactct
     6241 acattttctt ttatagtttt gttttcattg attgttggga ttttattcac agtaatctca
     6301 tatttcttta tcaaagaaat atctattttg cttggtgcaa cagataagtt attaccatat
     6361 tgtataactt atggtaaagt tatgatttta tgtacaccat tttatatttt aaaatttata
     6421 tttgagtact ttgcaagaac tgatggaaat tctaaattta gtttatttct atcagtcatt
     6481 ggtggtgtaa caaatataat attggattat gtatttatta aatattttgg aatgggtctt
     6541 ttaggagctg cagttgcaac tgctataggt attattttaa cttgtgtttt aggtattatt
     6601 tacttcttat ctaataaatc tacactaaaa ttaagaaaac caaaaaccga ttttagactt
     6661 ataagagata ctatgataaa cggttcttct gaaatggtta cagaattatc tacaggaatt
     6721 acaacattct tatttaatgt agtagcttta aaattagcag gagaaaatgg acttgctgct
     6781 cttactatag tattgtatgc tcatttttta atgacatcag tctatctagg attcgctgct
     6841 ggagtgtctc cattaataag ctataatttt ggtgctgaaa acagtgataa attaaaagaa
     6901 acatttaaac attctctaaa atttatattt gtttcttctc ttttagtgtt tattattgct
     6961 ttagtatttg caccatttat tgttagggtc tttgtaagtc cagataacac agtatttaaa
     7021 ctagccttac aaggattaaa aatatttgca tttgcttttt tgtttgttgg tataaatata
     7081 tttgcatcag gattttttac agcatttcac aatggaaaaa tttcagctat tatatctttt
     7141 agtcgtgcct ttgtttttat aatcatagga atcataattc ttcctcctat gttaaacatg
     7201 actggattat ggcttacagt tccatttgct gaggttataa ccatatttat atctattcta
     7261 tttataaaaa aatataaatg tagatataag tattaaaaat taatacttaa aatcaacatt
     7321 tattaaaact aataaacctg ctttaaaata caaatttaca aatttgattt ttaagcaggt
     7381 tttattttag ttataataag tcatttgcat actctttaat tggtgctttt ctaagtaata
     7441 aaattataaa tattatgcaa ataactataa ttcctacctt tgttccaaat aaaataaaag
     7501 gattctgaaa tgaataaata attttttcta aatacaatag cattttatgc atatttttag
     7561 ttgcaaaatt aactatataa attatcatta atatcggtaa tcctatcaat atagtaatac
     7621 tagtaacttt tctaactcta tatgtaaaag ctccaagtaa cactcctata aaacctatac
     7681 atatttcatt tatacatatt tgtacaaaat aatttaaata agttagtggc atacttgatg
     7741 ttgaaggatc tatcagtgct gatatagatg tccaaatcat atctctcttt agtaaaactg
     7801 atagttctat actgtaacct gttataattt ctataaataa cttcgataaa aaaatcaaaa
     7861 ctatacctaa aatagaaatc acaaagctta aaataattaa atctatgaca atagctttta
     7921 tacaactttt tctatctgct cttatactta aagctcctga aaagtcttta tttgctatat
     7981 ttactccata cacaaatagc agtatagtta tatatgttaa aataggattc acaatcgtgg
     8041 ataaattagt tttagatgct tctccaaaaa tcttgagaat aaacactggc aaaatattca
     8101 taacaattcc cacaatcata aatataatta tatacaattt agtattttta ttaaaaaatt
     8161 ttatatatgg ctttaattca ttcaattaca attcctcctt cttagtcatg ttaacaaaca
     8221 tatcttgtag ccctatgtat cctacatcaa tatttgaatt tttaagtatt ttttcatcat
     8281 tttcactaaa atcaccatag taaaaataag cgactgcatt tccaaatgcc tttttaggtt
     8341 ttatattttt tatacattct aatttttcta actcttcttt atttccagta atataatgag
     8401 ctttttgttt tatgacatca atttcttcat ctataataat ttttccctca tttaatatta
     8461 ttacatgctc cagtaaatca tctatttcat caatcaaatg agttgatatt attattgtcc
     8521 ttggattttt tatataacta tctaaaatta tgttataaaa ctcttgtcta tttactgcat
     8581 ccagaccaat tgttggctca tcaaatatgg tgatagctga attagaacaa atacctatta
     8641 tatttgaaag tatagttttc atacctcttg acagttgttt atactttttt ttagtattta
     8701 aatcaaaata tttgcataat tcttcttcta agcctttatc ataactttta taaaaactag
     8761 aagaaaattc aaatatctga cctactttaa aatctggact ataaaattct ttttccctga
     8821 cgatacaaac ttcttccaaa acttttatat cttcttttgg gttctttcct aatatttcta
     8881 tctcaccttc attttgaatt aactgattta ccattatatt taataatgtt gtttttccag
     8941 ctccattctt acctaataaa ccatatatct tatttttttc aaagtttaga gacatattat
     9001 taaaaatatt ttgcttctta aaactgtgag ataaattttc tatcttaata gaactactca
     9061 tatattaatc ctccttgaaa ttaattataa tatcaaccaa ttcttctcta tttatttcta
     9121 atttgttagc ttcttgaagt aggtttttta caaaattatg tttaaaattt tcttttctag
     9181 cttcttttat aatagttttt gcaccatctg atacaaacat ccctatcccc ctcttcttat
     9241 ataaaatatt tttatcaacc aatatattta taccttttaa tactgtagct ggattaattt
     9301 tataaagctt tgaaagctct gttgttgatg gaacctgttc ttcttctttt attccatttg
     9361 atagtatctc atcttcaatt gctcgtgcta tctgaataaa tataggttct tcattattta
     9421 atactaattt cataggttcc tcctttcttc atcagttagt tactcaacta attaactata
     9481 taacttataa tatcttgaaa aatattttct gtcaatacta aataaaaaac agagggaaaa
     9541 ttccctctgt tttttgttct ttatatttat aattaaattt tgatttttgt aatcctatcc
     9601 cataagttaa aaattttaat aatctgttgt atcttcattt tttaatattt tacatattga
     9661 gctagttcct aacctttctg ctcctgcctc tataaatttt tctgcatcag aaattgattt
     9721 aactccccct gcagctttta tttttacatt ttttccaaca tgctctttca taagctttat
     9781 atcttctaaa gtagctccac ctgttcccat tccagtagat gtttttataa aatctgaacc
     9841 tgacattgtt actatttcac acatttttat tttttcatct tcatctaaat aacatgtctc
     9901 tataatgact tttaatactt tatctcctat agcttttttt atttctttta tttcttttcc
     9961 tatattatca taatctttat tttttatatc tgaaatgttt acaaccatat caacttcatc
    10021 tgctccattt tcaatagcat cttttgcttc aaatactttt gtagcagtag tttgatatcc
    10081 caaagggaac cctatcactg tacatatctt tattttacct tttagatatt ctgatgctct
    10141 tttcacatat gatggtggta tgcaaactga tgctacactc atatctacag cttcatcaca
    10201 taaaatttta atatcttccc atgtagttgt agcttttaaa atagtatggt ctactgtttt
    10261 taatatatgt ttcataaaat cctcctaaat ttataattaa tataattaga ttactttttt
    10321 aaatgcaatt ttctctttgc aatattcagt atcatatcaa cctcttcaac tttaaaaata
    10381 gtcattagta gtgtataaat tccacctcca actataactg aaatagctag tgatacaaac
    10441 tcattaaatg ttcctactcc caaaattcca aatataaatt tatacgtaaa gtatgataaa
    10501 acacccataa ttaaagatgc aactaccgat ttcaaagttg cttttattat tttatcttgt
    10561 ccaaaatatc caacttttct ctttaggttc aagaagagta acaatataca tgcaattgat
    10621 gatgaactag ttgcaagagc aagaccacca tgagccattg gttttattaa aactaagtcc
    10681 aatactatat ttacccctac agatataatc ccatttacca taggtgtttt tgtgtcttgt
    10741 aatgaataaa aaacctttcc caaaatatct cttaagccaa atgcagtcat accaactgca
    10801 taaaaaatta aggcagttgc tgtcatttgg gttgccctcg catcaaaagc acctctctca
    10861 aaaatgattc taacaacagg agttgcaaaa aaaatagaag caactgaaat aggaatcata
    10921 gaaattatta tcatatttat actggattta actgaactag taaacttctt ttgattattt
    10981 tctgcactta acttagataa cataggatac ataacagata ctattgaagc tgtaaatgtc
    11041 cctgtaacaa aaccatttaa tctatctgca taagtaagtg ctggaatgct tcctttaact
    11101 aatgttgagg ctaaagttgt atctaccaat gagttcactt gattaacagc aacacctata
    11161 aatactggtg aaagtaatgc tagtaattta ataaggctat catctttaaa gtttaagtag
    11221 tataagtatt tgtagttcgt ttttttaaca aaaaacatgt aaaagagcag ttgaactacc
    11281 atagcaacca cagcaccaat tggaagtatg tatggtccaa atacggtact taacattatt
    11341 gaaataatta ttactatatt atagggtata cttccaaatc caactacaat aaagttctct
    11401 ttaatttgta aaaatgctga cataacactc gtaataccta tgaatattat tcctgttctg
    11461 aacctcccat gactaaagtc acagggttcc tgcttcatag aattttgcat actaaaatat
    11521 gtcttactaa ttctccacag gctatccccg tagttcctac ggttcttaca tacgttattt
    11581 attttgaatt gttattagtc ttaatccttc ttttaatata tttatacttg catttatatc
    11641 tctatcgtga gtttcattac aactaggaca aatccattct cttatattta agttcttaac
    11701 ttcctcgttt ttatacccac atttattgca tatttgtgaa cttgcaaaga atttacctac
    11761 ctttacaatt tgtctaccat accaattagc cttgtattct aattgacgaa taaactctga
    11821 ccatgataca tcagaaatta agcgagatag tttacgattt ctaatcatat tctttacttg
    11881 taaatcttct atgcaaataa tatcgttctc ttttattaat ttagtagata gtttttgtag
    11941 aaaatcattt ctttgattag ctatatgttc ttgaagtctt gcaactttta atcttgcttt
    12001 atttctattt aaactaccga ttgtttttct cgataattct ctttgtaatt tagcaagttt
    12061 gtttaatgac ttcttaagat acttaggatt ttctataaat tctccacaac ttgagataca
    12121 aaattcttta attcccaaat ctaaacctat atgattatta gtattttcaa atacttcaat
    12181 atctacatca atacagcata atgatacata atatctacca cttggttctt tagatatagt
    12241 agcattaagt attct
//
LOCUS       DAMKNB010000098        12138 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.104, whole genome shotgun sequence.
ACCESSION   DAMKNB010000098 DAMKNB010000000
VERSION     DAMKNB010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 12138)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12138)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12138
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.104"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            712..1890
                     /locus_tag="PC494_003116"
     CDS             712..1890
                     /locus_tag="PC494_003116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HDF3913595.1"
                     /translation="MKYHIFLIITTLLIIELCNIYICKIASFGNKNITIHKNYKYIFL
                     IKPLTFLIIIFTKLPLPLYYILFYIVSHKLLLSRKSSTNNHFIPNMAVISFCILHLIT
                     VSTISLVKNTSPDIIFANMTYKLISILIASILDFILWYSMNKIKEHIYIITQNQIEFS
                     LFLKFIWFTLGYILFDSIQITFAPPSSLTSYFILGSNILLILQLIIFINHIYSIEKNI
                     YLEKEHHRLKMIKQEQLLKVNLLKKKANIDELTSAYNRKFAFEKIQHYIDNNLLFSLI
                     YIDLDKLKTINDTYGHLAGDNYIINFSSIVIENLGIDDIFARIGGDEFIVIMPKSNEN
                     TTKEFIEKISKIMDNKISFSYGIVEVSSENKMTVEEIINIADIRMYTNKQNNHKRNNN
                     "
     gene            2240..3121
                     /locus_tag="PC494_003117"
     CDS             2240..3121
                     /locus_tag="PC494_003117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HDF3913596.1"
                     /translation="MPAYLFDSNSITNIYRVFSILLSFIVTGLYFSYKNHKNNKINFE
                     AVLEDKKNLIFLLSLMFGMYLYLCLSLSIYYTVGNVLILKLYGIKSAIIVLVGNYIAE
                     RYSFRITQIKGYDIKNQIEYVESVKTEYEINKLNDIVYTDLLTGFYNRPFVNQKLSEW
                     TSNHYKFTLCFTDLNSLKPVNDKFGHQFGDKYISTTAQIIKKLINVENSLLFRYGGDE
                     FLFLLQNTSCVEAEKIMININYELSKLSNTDEYPYALSISYGLVEWDGISDIETLISK
                     ADSLMYENKLKNKSTLN"
     gene            3330..3479
                     /locus_tag="PC494_003118"
     CDS             3330..3479
                     /locus_tag="PC494_003118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008819224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HDF3913597.1"
                     /translation="MTTVAEGIETSFQKDFLQEIDCDMLQGYVFSRPLPIKDFEKLMF
                     QNSSN"
     gene            complement(3739..6306)
                     /locus_tag="PC494_003119"
     CDS             complement(3739..6306)
                     /locus_tag="PC494_003119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002602373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate, phosphate dikinase"
                     /protein_id="HDF3913598.1"
                     /translation="MIYYVLPLEHKQATIEIVGGKGMSLSKLLTAGIPVPDGFHVTTA
                     SYQIFVETNHIQSRINKLLDGIDSNNTSQLEDVSKKIGELFHNGEMPQEVSDAIKTAY
                     AGLGNISVAVRSSATAEDLPDASFAGQQETYLNIQGEDKVIDAVKRCWASLWTARAIA
                     YRVKNNIKHEIVALAVVVQKLAFSDSSGIMFTLNPINGRRSEMIINAAWGLGEAVVSS
                     LVTPDTIVVDKDSERIISYEVANKEIMTVRTSEGTEETMVPERLRKKYALTRNQVMQL
                     IQLGKKIEKYYQMPMDVEWALEKDKLYIVQARPITVLPPEWVLPEQDVVYTKGSLAEH
                     LPNPVTPLFATLGLEIVNRASELLWIDMFGKSAKKLLPKNGAYTVINGYVYLSAKSKP
                     LLIAIKSLSPRSLRRTLMNSVARWETARKGYEDAIKQWEEKPLHTMNAHQIMEGIQTI
                     FYAACIYFTRIQLTLPAASISETLFTKLFQGAVRRAGITDTSVFLLGFDTIVLQSEKA
                     LWGISEWVKQNNSINLYLQNSSAIKIAEDFMSSVVPVGVSQEVWIEWKNRINKYFKEF
                     GRTAYEFDFAHSTPQETLTPTFESVKTFVEGKGESPFLRQTTFEKRRKHAEEEILQHI
                     GGLRKKLFFKLLHWAQETSPMRENAIYLMGMGHPLIRCMFQKISERFIRGGAISHLDD
                     IYWLTKSELEVLIEQLDKNKSLSDMNGIIPVRKAELKKYMGYVSPSKLPEKNKKTISQ
                     EPQKQKDGKIVLTGIGTSTGVVTAPACVLNSPADFESFQPGSVLVAVTTTPAWTPLFS
                     SASAIVTDIGGPLSHSSIVAREYGIPAVMATHIATRTIKSGQMITVDGLAGTVTFDE"
     gene            complement(6309..6914)
                     /locus_tag="PC494_003120"
     CDS             complement(6309..6914)
                     /locus_tag="PC494_003120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002591427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDF3913599.1"
                     /translation="MPKGIVLTPEQQAERREKIVAVALSLMAENGFQKTSMREIAVLA
                     NMGKSSLYDFFKTKDEIVVYAVEKEIEKTIQQVHRIIDGEPSPQQCLRKIMLNHLRFP
                     EQYRTVLMWLNTESDYLEEEYRKRLKDARYAYQDIIKSVIDNGVTTGIFRKTDTALVT
                     RLLINSMLSISYTSRPSDSSEKMLDETMNIFLHGIMNDGGE"
     gene            complement(7288..8748)
                     /locus_tag="PC494_003121"
     CDS             complement(7288..8748)
                     /locus_tag="PC494_003121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent glyceraldehyde-3-phosphate
                     dehydrogenase"
                     /protein_id="HDF3913600.1"
                     /translation="MFNELKTKENVYKNLINGKWVESNSRKPIEIYSPIDNSLVGKVQ
                     SMTKHEVDEVIKNTKESIKVWAEMPVYKRANIFHKAADLLLENIDEIANVLVLEIAKD
                     IKSARAEVERTADFLRYTADVGKNMEGEAISGDNFPGGTRNKMSYVSRVPLGTVLAIS
                     PFNYPVNLSMSKIAPALIGGNAVVLKPATQGAISALHVVEIMRKAGIPDGVLNTITGR
                     GSEIGDYVVTHKGINFINFTGSTEVGQHISKISGMVPLLLELGGKDAAIVLEDADLDF
                     AAKNIVSGAYSYSGQRCTAVKRILVQESVADKLVGKIKPLVEKLTIGNPMDEVVITPL
                     IDNKATDFVQGLVDDALHKGAKLITGNVRKNNLFYPTLLDNVNVDMKIAWEEPFGPVL
                     PIIRVKDINQAIEIANQSEYGLQSSVFTSDIDKAFYIADKLEVGTVQINNKTERGPDH
                     FPFLGVKASGMGTQGVKYSIEAMTRPKAVVVNVREL"
     gene            9103..9681
                     /locus_tag="PC494_003122"
     CDS             9103..9681
                     /locus_tag="PC494_003122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDF3913601.1"
                     /translation="MAKSFTEIEKDNIRKRLISECELNWSKYGYKKTNIDELCSKSGI
                     AKGSFYTFFDSKEKLFFEVLNGIQNRLISSVDEILSNMPPKEGFAKSLKMLYRLYDKN
                     PFLYSPNNPDFISLINKLPQDMFLQLESNNIQSFYDLIERHNLKLKIEKEKVFGVCNA
                     LLSSLLVKENIEYNYIEVFDFMVDNLVEHILE"
     gene            9972..11222
                     /locus_tag="PC494_003123"
     CDS             9972..11222
                     /locus_tag="PC494_003123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDF3913602.1"
                     /translation="MVKSSNTFNKNFNLMILGQIISLFGASILKFALSLYILDITGKA
                     EIFATILAVSSIPIIVFSPIGGAIADIFNRRNLMVIFDFSSSLTVLILAVFLFNNNGS
                     ILLVGIIMTILSVISTMYQPTVQSSTPLLVDNEHLMNANGIVAGVASLTNIAGPVLGG
                     VLYGVIGINAIIVISCVSFFLSAIMEIFIQIPFIKQEQNSNIIKTIFTDIKDGIVHIC
                     KENRFILKILFLAIAINLFLSSMLIVGIPYIVKITMGASNFLYGLAEGAISFSSLVAA
                     VSIGIFSKHLKITNLHISFIICAVMFIPMAVSVYPFILNTGFPVPFLIFIVSSMLIFF
                     TTTLISIYVITVTQLKTPNELLGKVMSILFAGTAIAMPLGQVMYGKLFDLLSDRVYII
                     ILVVGFITLLIAFVSKITLRNENL"
     gene            11383..11952
                     /locus_tag="PC494_003124"
     CDS             11383..11952
                     /locus_tag="PC494_003124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HDF3913603.1"
                     /translation="MSYMPTLEQAWEILRKYNKEEFHIRHAQIVSGVMRYYAKEYDPE
                     RVEFWEIVGLLHDLDFEMYPDEHCVKQRELMTELDLDKSIIDSTISHGYGLTGSDVKP
                     EQFMEKVLFAVDELTGLIGAAAIMRPSKSVSDLELKSVKKKFKDKSFAAGCSRDVIRS
                     GAEMLGWELDKLIQTTIEAMRSLIPEMAI"
BASE COUNT         4200 a         1995 c         1678 g         4265 t
ORIGIN      
        1 taactattat atttgctata tgtaattgta ctatacttgg acatatagtt atcatacata
       61 ctatatgtaa ttactatact tatacacata gttatcatac atgctatatg taattactat
      121 acttatacac ataactacta tatttactat atgtaattat actatacgtg gacatatagt
      181 tatcatacat actatatgta attactatac ttggacacat aattattata tttgctatgt
      241 gtaattatac tatacttgga catatagtta tcatacatac tatatgtaat tactatactt
      301 atacacataa ctattatatt tgctatatat aattactata cttggacaca tagttatcat
      361 acatgctata tgtaattact atacttatac acataactat tatatttgct atatataatt
      421 actatacttg acacatagtt atcatacatg ctatatgtaa ttactatact tatacacata
      481 actattatac ttaccataca taattactat atttggacac atagttatca tacatactgt
      541 atattaagat ataatacttt ctaaatttta tataacacag acacatgcaa taaaaaagaa
      601 ggtatccata ataagctctt tgcatgtacc taaataaaaa ctgtaaaata gaatatataa
      661 aatctaatct attttaagta aatacaattt cactttaaaa gaggatgtac tatgaaatac
      721 catatatttt taatcataac tactttatta ataatcgaac tatgtaacat ttacatatgc
      781 aaaatagcat cttttggaaa caaaaatata actatacata agaattacaa atatattttt
      841 ttaataaaac cattaacctt cttgataata atattcacaa aattaccatt accactatat
      901 tatatattgt tttacatagt aagtcataaa ttgctcttaa gcagaaaaag ttctactaac
      961 aaccatttta ttcccaatat ggcagtaata agtttttgta ttttacacct tattactgta
     1021 agtacaatat cacttgttaa aaatacaagt ccagatataa tatttgcaaa tatgacctat
     1081 aagttaatta gtattttaat agcttctatt ttagatttta tcttatggta ctctatgaat
     1141 aaaataaaag agcatattta tataataact caaaatcaaa tagagttcag tctattttta
     1201 aaatttatct ggttcacttt aggatatata ttatttgata gtatacaaat tacatttgct
     1261 ccaccaagtt ctctaacttc ctactttata ttgggaagta acatattatt aatcttacaa
     1321 ctaattatat tcatcaatca tatatattcc attgaaaaaa atatttattt agaaaaagaa
     1381 catcatagac taaaaatgat aaaacaagaa caattactaa aagtaaattt attaaagaaa
     1441 aaagctaaca ttgatgaatt aacatcagca tataatcgaa aatttgcttt tgaaaaaata
     1501 cagcattaca ttgataacaa tttattattt tcattgatat atatcgattt ggataaatta
     1561 aagacgataa atgatacata tggacattta gctggggata actatattat taacttctca
     1621 agtatagtta ttgaaaactt aggaatagat gacatatttg ctagaatagg aggagatgag
     1681 tttatagtta ttatgcctaa atctaatgaa aacaccacaa aagaatttat agagaaaata
     1741 agtaaaatta tggataataa gatatctttt agctatggta ttgtagaagt ttctagcgaa
     1801 aacaaaatga ctgtagaaga aattattaat attgctgata ttagaatgta cactaataaa
     1861 caaaataatc ataaaaggaa caataactaa aatgaatatt tacatgagct tacttgtagt
     1921 ctcactatgt tttttatctt attatctcta tcattataat ttttttaaat atctagacat
     1981 aatgattaat aactctaaaa ataaatacaa agtatatatt gtatactctc tttttaatta
     2041 tttaattttt attatttgta cttatttaag gttacaccta gttataaatt ggacaatttt
     2101 tatgttaatt ttatttatgc aaattaaagt aacttacaaa ctttccacaa taaaaaacct
     2161 tttttattcg ttaaactgct ccatcattgg tttagcaata aatatatttt ttaggtcttt
     2221 aatgtcaata gtgttaaata tgccagcata tttatttgat agtaattcta ttacaaatat
     2281 ttacagagta ttttctatat tgcttagttt tatagttaca ggattatatt tcagttataa
     2341 aaatcataaa aataataaga ttaactttga ggcagtttta gaggacaaaa aaaacttaat
     2401 tttcttattg agccttatgt ttggaatgta cttgtatcta tgtttgagtt tgtcaatata
     2461 ctatactgtt ggaaatgtat tgattttaaa attatatgga atcaagtctg ccataatagt
     2521 tttggtaggt aactatattg cagaaagata tagctttaga attactcaaa taaaaggtta
     2581 tgatattaaa aatcaaatag aatatgtaga aagtgtaaag acagagtatg aaattaataa
     2641 attgaatgat attgtatata cagatttact gacaggcttc tacaatagac cttttgtaaa
     2701 tcaaaaacta tcagagtgga catcaaatca ctacaaattt accttatgtt ttactgattt
     2761 aaatagctta aaacctgtaa atgataaatt tggacaccaa tttggtgata aatacatatc
     2821 cactactgct caaataataa aaaaacttat aaatgtagaa aattccttac tatttagata
     2881 tggtggagat gaatttttat tccttttaca gaatacaagt tgtgtagaag cagaaaaaat
     2941 aatgattaat ataaattatg aattatcaaa attaagtaat actgacgagt atccttatgc
     3001 tctttccata agctatggat tagttgagtg ggatggaata tccgatattg aaactttaat
     3061 atcaaaggca gattctttga tgtatgaaaa taagcttaaa aataaatcta ctttaaacta
     3121 gctagttaag atattctaca aaatatatgt tataagagag tactaagaat gtcaaaatat
     3181 atagattttg caaatattga atacagttta ctaatgaatg cactggatgt aagtgttagt
     3241 aaacacctat tagatgaaca ctttactgtt gtttgggcta atgaccgtta ttatgaaatg
     3301 ttcggctata cctagctaaa aagttaaaaa tgaccactgt agccgaggga atagagacca
     3361 gttttcaaaa agatttcttg caagaaatag actgtgatat gttacaagga tacgtgttct
     3421 ctagaccttt accaataaaa gactttgaaa aacttatgtt tcaaaactcc tccaattaac
     3481 aatataaaat tgcttattat aagtgatatt attgtatcaa caaataaagg aattgtctca
     3541 aaattgattt tttctaatca aatttttatt ttgagacatt ctcatttttt tgcataagaa
     3601 aatacccacc aagctacggt ttttcttacc gctgttcggt gggtattagt agtattatga
     3661 aatctgaaaa ctttaagtat tactacttcc gctaacgcaa tcacaaaggt cgaaagcttc
     3721 aaagcgaaaa taggcttttt actcatcaaa cgtcaccgta cctgccaacc cgtccaccgt
     3781 tatcatttgt ccgctcttaa tagttcgtgt ggcaatgtgt gtagccataa cggctgggat
     3841 gccatattca cgtgcgacaa tgcttgaatg gctaagagga ccaccaatgt ccgttacaat
     3901 cgcacttgca gatgaaaata atggtgtcca tgctggagtt gtggtaactg caaccaaaac
     3961 acttccaggt tgaaagcttt caaaatctgc tggactattc agtacacaag ctggagccgt
     4021 cacaacacca gtactggtac caatgcccgt caacacaatt ttcccatctt tctgcttctg
     4081 tggttcttgt gatatagttt ttttgttttt ctctggcaac ttggatggtg acacataacc
     4141 catgtatttt ttaagttcag cttttcgaac aggtattatc ccgttcatat cagatagaga
     4201 cttgttttta tccaactgct ctataagtac ctccaattcc gattttgtga gccaataaat
     4261 atcatctaaa tgtgaaatag ctcctcctcg tatgaatcgt tctgagattt tctgaaacat
     4321 acaacgaatc agaggatgtc ccattcccat caaataaata gcattttcac gcataggaga
     4381 ggtttcctgt gcccaatgga gcaacttaaa aaatagtttt ttacgcaatc cacctatgtg
     4441 ttgtaaaatc tcttcttctg catgttttct acgcttttca aacgtggtct ggcgtaaaaa
     4501 aggactttcc ccttttcctt ccacaaatgt ttttacggat tcaaaagttg gtgtaagtgt
     4561 ttcctgcggt gtggaatgcg caaaatcaaa ctcataagcg gtacgaccaa actctttaaa
     4621 gtacttattg attcgatttt tccattctat ccatacttcc tgtgaaactc caacaggcac
     4681 aactgaagac atgaaatctt ctgctatctt tattgcagaa ctgttttgca gataaaggtt
     4741 gatgctgtta ttttgcttta cccattctga aataccccac aacgcctttt ccgattgcag
     4801 aacaatcgta tcaaacccaa gcaggaaaac ggaagtatcc gttataccag cacgtcgaac
     4861 tgctccttga aataattttg taaataatgt ttcactgata gaagcagcag gcaatgtaag
     4921 ctgaatcctt gtgaaataaa tacatgcggc ataaaatatt gtctgaatac cctccataat
     4981 ttgatgggcg ttcatagtat gcaggggctt ttcttcccat tgtttaatag catcctcata
     5041 tccttttcgt gccgtttccc agcgtgcaac gctgttcata agtgtcctac gtaaagagcg
     5101 tggggaaagg gatttgatag caatcaaaag tggctttgat ttagcagaaa gataaacata
     5161 tccattaata accgtatatg ccccgttttt tggtaataat tttttcgcac ttttaccaaa
     5221 catatctatc cataaaagct ctgatgcacg gtttacgatt tcaagaccaa gcgtggcaaa
     5281 caaaggtgta acaggatttg gcaagtgttc tgccaaactt ccctttgtgt atacaacatc
     5341 ctgttctggc aatacccatt ctggtggcag aacagtaatt ggacgagcct gaacaatgta
     5401 caatttatct ttttccagtg cccactctac atccataggc atttgataat acttctcaat
     5461 tttctttcca agctgtatca gttgcattac ctgattacga gtaagagcat atttttttct
     5521 caacctttca ggaaccatgg tttcttctgt tccttctgaa gtacgaaccg tcataatctc
     5581 tttatttgcc acttcatacg atataattcg ttcggaatcc ttatccacta cgattgtatc
     5641 gggtgtaact aagctagaaa ccaccgcttc accaagcccc catgcagcgt taataatcat
     5701 ttcgctacgt ctaccattga ttgggtttaa cgtaaacata ataccagatg aatcggaaaa
     5761 tgcaagcttt tgtactacaa cagcaagtgc gacaatctcg tgctttatat tattcttcac
     5821 acgataagca atagcacgag ctgtccataa ggaagcccag catctcttta cagcgtcaat
     5881 aactttatct tcaccttgta tgttaagata agtttcctgc tgacctgcaa aagaagcgtc
     5941 aggtaaatct tcagcagtcg cagacgaacg gacagccacc gatatgttcc ctaatccggc
     6001 ataagccgtt ttaattgcat ccgacacttc ctgtggcatt tctccattat ggaaaagctc
     6061 ccctattttc ttagatacat cttcaagttg gctggtatta ttggaatcaa taccatctag
     6121 cagtttatta attcgagact gaatatggtt cgtctcaaca aaaatctggt atgaagcagt
     6181 cgtaacatga aaaccgtctg gcacagggat acctgctgtc aatagttttg ataaagacat
     6241 cccttttcca ccaacaattt caatggttgc ttgtttatgt tccagtggca agacataata
     6301 aatcataatc attcacctcc atcattcata attccgtgca gaaatatatt cattgtttca
     6361 tccaacattt tttccgaact atccgatggt cgtgacgtgt agctgattga taacatggag
     6421 ttaattaaca aacgtgtcac aagagcggta tccgttttgc gaaagatgcc tgtggtcaca
     6481 ccattatcaa ttaccgattt tataatatct tgatatgcat aacgagcatc tttaagtctc
     6541 tttcgatact cttcttctaa ataatcagat tctgtattta accacatcag tacagttcta
     6601 tactgctctg gaaatctaag atgattaagc atgatttttc taaggcactg ttgtggtgaa
     6661 ggttcaccat caataatcct atgaacttgt tggatagttt tttctatttc tttctcaact
     6721 gcatatacaa caatctcgtc tttcgttttg aaaaaatcgt atagacttga ctttcccatg
     6781 ttggctaaaa ctgcaatttc tctcattgat gttttttgga atccattttc agccatgaga
     6841 ctcaaagcaa cagcaactat tttttctcgg cgttctgctt gttgttcggg tgtaagcaca
     6901 attccttttg gcatagggcg atacctcctt ttagcgacca ctggtcgttt cttttttatt
     6961 tatcatacag cgaccaacgg tcacttgtca aggttaattt ttttcattgt atatggtact
     7021 cgagataaaa atgttcattt tagaatttgc tctatttaag tagaaatagg cttcatcatt
     7081 agaaaacaag actataaatt tgagatattt atcatgttca aatttcatca atatcaaagt
     7141 ttaagatatt aataaaaaaa gaattactaa gaaataacat ataaagattc aaaaaaggag
     7201 ttgaacttaa aatttaatta caaaaaatca aatttaagac aactccttta ttctttatct
     7261 ctactattct ttatctctat ttatttatta caactcccta acatttacca ctactgcctt
     7321 aggtctagtc atagcctcga ttgaatactt aacaccttga gttcccatac cagatgcctt
     7381 tacacctaaa aatgggaagt ggtctggacc tctttcagtc ttattattta tttgaacagt
     7441 accaacttca agtttatcag ctatataaaa tgccttatca atatcacttg taaatactga
     7501 tgattgaagc ccatactctg attgattagc aatttcaatt gcttgattta tatctttaac
     7561 tcttataatt ggaagtactg gaccaaatgg ttcttcccaa gcaattttca tatcaacatt
     7621 tacattatct aacaatgttg gatagaataa attatttttt ctaacattgc ctgttattaa
     7681 ctttgctcct ttatgtaatg catcatcaac caacccttga acaaaatcag ttgctttatt
     7741 atctataaga ggagtgataa ctacttcatc cattggattt ccaattgtca acttctctac
     7801 caatggcttt atttttccga ccaatttatc cgccacactc tcttgtacta aaattctctt
     7861 tactgccgta catctttgtc ctgaatatga atacgctcca gatactatat tcttagctgc
     7921 aaaatctaag tctgcatctt ctaatactat agccgcatct tttccaccaa gctccaataa
     7981 taatggtacc attccagata ttttagatat atgctgacca acttcagtac taccagtaaa
     8041 gttaataaaa ttaattcctt tatgcgttac aacataatct cctatctcac tacccctacc
     8101 tgtaatagta ttaagtactc catctggtat cccagctttt ctcataattt ctaccacatg
     8161 aagtgcgcta atagcccctt gtgtagcagg ttttaataca actgcatttc caccaataag
     8221 tgctggagca atctttgaca ttgataaatt tacaggataa ttaaaaggag atatagctaa
     8281 aacagtacct aatggaaccc ttgaaacata agacatctta tttcttgttc caccagggaa
     8341 attatctcca ctaatggctt caccctccat attttttccc acatcagctg tgtatcttaa
     8401 aaaatctgct gttctctcaa cttctgccct tgcagatttt atgtctttgg ctatttcaag
     8461 taccagtaca ttagctatct catctatatt ttctaacaat aaatcagcag ccttatgaaa
     8521 tatattggct ctcttgtata caggcatttc agcccatact tttatactct cttttgtgtt
     8581 ttttataacc tcatctacct catgttttgt catagattgt actttcccaa caagagaatt
     8641 atctattggt gagtaaattt ctattggctt tctcgaatta gattctaccc attttccatt
     8701 tattaaattt ttatatacat tttcttttgt tttaagttca ttaaacatat ttttattcct
     8761 ctctctgata taactttgtg tatttaaatt atagccattt attcgttatg taaacatttc
     8821 tttttttcat aaacgtttac ctataaaaaa aattttaagt taacgttttt ctacattctt
     8881 ctattttaat aacatactcg ctccaaatct atataggtca cactttaata tcaatatact
     8941 aatataccaa tataccaata taccaatata ccaatatacc aatataaata ttataaacat
     9001 aaatcacttg acaaatttat aagtagacaa tattatatat ctatgactca aaatattttt
     9061 aaagtcatat atatcatata tagatagaaa ggattgataa acatggctaa aagttttaca
     9121 gaaatagaaa aagacaatat aagaaaaaga ctaatttcag aatgtgaact caactggtct
     9181 aaatatggat acaaaaaaac taatattgat gaactttgtt caaaatcagg aattgcaaag
     9241 ggttctttct atacattttt tgattcaaaa gaaaagttat tttttgaagt attaaatgga
     9301 atccaaaaca gacttatatc atcagtagat gaaattttaa gtaacatgcc tccaaaagaa
     9361 ggctttgcaa aatccttaaa aatgttatat cgattatatg ataaaaatcc atttttatat
     9421 tcaccaaata atcctgattt catcagccta ataaataaac tacctcaaga tatgttttta
     9481 caacttgagt ccaataacat acaaagtttt tacgacttaa ttgagagaca caatctcaag
     9541 ttgaagatag aaaaagaaaa agtttttggt gtttgtaatg ctctactatc aagtctattg
     9601 gtaaaagaaa atattgaata taactatatt gaagtgtttg actttatggt ggataatctt
     9661 gtagaacaca tacttgaata acaatttaaa ataatttttc taagtatttt tttatactaa
     9721 ataggattaa tatgattgaa ttaatacaaa aaataaacaa tataatttat aaaataaatg
     9781 ataaactaaa tatcacacaa aacttataga ccctagagca aacccattcc actctactct
     9841 aagccatcta taatagtttg tatatttcta ataatattag atattaaagt aagaaaaaaa
     9901 ttccttataa taattgctat tatatcaatt attataaata ttttaataat cttagatagg
     9961 taggtacata tatggtaaaa tcctcgaaca cttttaataa aaacttcaac ttgatgatat
    10021 taggtcaaat aatctcattg tttggtgcat caatacttaa atttgcttta tctttataca
    10081 tacttgatat aactggtaaa gcagaaatat ttgctactat actagcagta tcttcaatcc
    10141 caattatagt attctcccct attggtggag ctattgcgga tatattcaac agaagaaact
    10201 taatggttat ttttgatttt tcaagtagtc ttacagtact aatcttagca gtattcttat
    10261 tcaacaataa tggttcaata ttacttgtag gaattattat gaccatatta tcagtcataa
    10321 gcacaatgta tcaaccaact gttcagtcaa gtacacccct tttagttgat aatgagcatt
    10381 taatgaatgc aaatggtatt gtagctggag ttgcatctct tacaaatatt gcaggacctg
    10441 tattaggagg tgtcttgtat ggtgtgattg gaattaatgc aattatagtt atcagttgtg
    10501 taagtttctt tctatctgca attatggaga tatttataca gattcctttt atcaaacaag
    10561 agcaaaacag caacattata aaaactatat ttactgatat aaaggatggt attgttcata
    10621 tatgtaaaga aaatagattt atactaaaaa tacttttttt agctatagca ataaacttat
    10681 ttttaagctc tatgttaata gttggtatcc cctatatagt aaaaatcact atgggagcta
    10741 gtaacttctt atatggtcta gcagaaggag caatttcttt tagttcactg gtagctgctg
    10801 ttagtattgg tattttctca aaacatctaa aaatcactaa tttgcatatt tcctttatta
    10861 tatgtgcagt tatgttcata ccaatggcgg tttcagtata tccatttata ttaaacacag
    10921 gatttccagt tccattttta atctttatag tatcatctat gctaatattt tttacaacga
    10981 ctcttatctc aatatatgtt ataacagtca cacaattaaa aactccaaat gaactcttag
    11041 gaaaagtaat gtcaattctt tttgcaggaa cagcaattgc aatgcccctt ggtcaggtta
    11101 tgtatggtaa actttttgat ttattatcag atagagtgta catcattata ctagtagttg
    11161 gatttattac attacttata gcatttgtat caaagataac attgaggaac gaaaatcttt
    11221 agatacaaag aatttagata taaagattta attttcacta atttctgaat ttaaatgcaa
    11281 aattgtgtat cagtatgttg acgttttaga aattgattga tataatcaat ggaaaataaa
    11341 ctttataaaa attcaaaata ttcagctaga ggagtgataa aaatgagtta catgccaact
    11401 ttagaacaag catgggaaat attaagaaaa tacaataagg aagaatttca tataagacat
    11461 gctcaaattg tatctggagt tatgagatac tatgcaaagg agtacgaccc tgaaagagta
    11521 gaattttggg aaatagttgg acttttacat gatttagatt ttgaaatgta tcctgatgaa
    11581 cattgcgtta aacaaagaga attaatgaca gagcttgatt tagataaatc aataatcgat
    11641 tctacaataa gtcatggata tggattaact ggttcagatg ttaaaccaga gcaatttatg
    11701 gagaaagtat tatttgctgt ggatgaactt actggtttaa ttggtgctgc tgcaataatg
    11761 cgtccttcaa agagcgtttc tgatttagaa ttaaaatctg ttaagaagaa atttaaagat
    11821 aaatcatttg ctgctggctg ttctcgagac gttataagaa gtggtgcaga aatgcttgga
    11881 tgggaacttg ataagcttat ccaaacaact atagaagcta tgagaagctt gattccagag
    11941 atggcaatat agctcctcca tacatatacc atagaagtta catctttaaa gagcatttct
    12001 ctttttgatg caacttcttt ttatattttg tagaataaaa agtttaatat tttaaactca
    12061 ctatataata aataatataa tgtataatag tcataaactt tctaacctta aaagtttcta
    12121 ataatcaata aacaattc
//
LOCUS       DAMKNB010000099        11884 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.105, whole genome shotgun sequence.
ACCESSION   DAMKNB010000099 DAMKNB010000000
VERSION     DAMKNB010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 11884)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11884)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11884
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.105"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            243..707
                     /locus_tag="PC494_003125"
     CDS             243..707
                     /locus_tag="PC494_003125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HDF3913604.1"
                     /translation="MATMTDIIEKFIKDLMEEDNSIQIQRNELANLFSCAPSQINYVL
                     TTRFTIDRGYYIESKKGGGGYVQIEKIRKSKDGHIRELLNEKIGSQISYKKAKELLEG
                     LKESDLINERELKLILYAIDDKSLCMPIYELKEKVRSNILKNIIIGLFSIEE"
     gene            714..1208
                     /locus_tag="PC494_003126"
     CDS             714..1208
                     /locus_tag="PC494_003126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UvrB/UvrC motif-containing protein"
                     /protein_id="HDF3913605.1"
                     /translation="MLCQKCNKNKASVYYNKIVNGEKTEMYLCSECAKENTEMNFNLD
                     MPFSMMDIFSNLGFQPKKELEEKLVCPKCNTTYSEFKNNGRFGCSECYNAFSSQVNPM
                     LQNIHGHIEHTGKAPKKSFYKISVENEIKELKEDLDRAIKNEEYELAAQFRDKIKYLK
                     GSID"
     gene            1224..2249
                     /locus_tag="PC494_003127"
     CDS             1224..2249
                     /locus_tag="PC494_003127"
                     /EC_number="2.7.14.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein arginine kinase"
                     /protein_id="HDF3913606.1"
                     /translation="MKENIVMKSRVRLARNLNNYPFPNKLDKECAMEIIEKVKNAFIN
                     SNLEQKEEFDFYKIEDLDQSKKMLMVEEHIISPDLAENDKSAVIVKKDKTISIMINEE
                     DHIRIQTICDDLNLEYAYSVANEIDDLLESSLEYAFNTKLGYLTSCPTNTGTGMRASV
                     MMHLPALSQLGYMDELYKISSQIGIAIRGIYGERTEALGNIYQISNQLTLGRTESNII
                     ENVSGLTKDAISKEIKAREILQKKLGIKLEDKIFRSIGTLENSRVMSSAEAMSHLSNI
                     KMGIEMNYIDKLDLRAIEQLMIGIQPAHQSIMYKSDDVENRDINRATYIRETLEKLRG
                     GMNCELQ"
     gene            2236..4683
                     /locus_tag="PC494_003128"
     CDS             2236..4683
                     /locus_tag="PC494_003128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HDF3913607.1"
                     /translation="MNFNRFTQRAKKAIDLAFESAKSLGHNIVGSEHILLGLLREEEG
                     IAAKVLSKVGFTEAYLEGKIVDMEGKGEEISEDIVLSPRSKQILELSGMFANKLKTNY
                     IGTEHILLAIIQEGEGIANKILNYAGVNDRTLAQLTIDMMGISDKNQYKAENSYTGNQ
                     NQAESKVLDKYGRNLTLYAKQNKIDPVIGREKEIQRVIQILSRRTKNNPVLIGDPGVG
                     KTAIAEGLATNIALGNVPETLKNKTLYSLEMGSLLAGAKYRGEFEERIKEVVDEVVKN
                     GNIILFIDEMHTIIGAGSTGEGSIDASNILKPALARGEIQVIGATTIDEYRKHVEKDS
                     ALERRFQPVMVDEPTKEDSIKILEGLRDKYEAHHKVKITDDAIKAAVELSTRYISDRY
                     LPDKAIDLIDEAASKVRLKENTPPSEIKKLELEIENIDKEKEEAVRCQDFEKAAKIRD
                     EQGLLKKQLEDVRERWNKSSKHSDLVDGEVIAEVVGLWTGIPVNKILEEEADRLLRLE
                     EILHNRVIGQEQAVKSISKAIRRSRAGLKDPNRPIGSFLFLGPTGVGKTELSKALAEV
                     QFGDENQIIRIDMSEYMEKHAVSRMIGSPPGYVGHDEGGQLTEKVRRNPYSVILFDEI
                     EKAHPDVFNILLQILDDGRLTDSKGRTVDFKNTIVIMTSNVGASTIGRQKTLGFSIAK
                     GDEEEKSQYEKMKENIMGELKQRFRPEFLNRIDDIIVFHSLNENHISKIVLLMAAKLQ
                     ERLKEMDIKLEMSDEAVKLISKSGFDLEYGARPLKRALQKELEDELSEAILKGNVKKG
                     SNVVAKVKDEKIVFETK"
     gene            4863..6236
                     /gene="radA"
                     /locus_tag="PC494_003129"
     CDS             4863..6236
                     /gene="radA"
                     /locus_tag="PC494_003129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HDF3913608.1"
                     /translation="MAKIKTKYVCQSCGYETAKWLGKCPECTKWNTFVEEIDQKSTKK
                     EVFIIDKSSSKPVSINSIESKEEERFTTDINELDRVLGGGIVKGSLVLVGGDPGIGKS
                     TLLIQVSSNVANLGKTVLYITGEESESQIKMRAKRLGINSENLYIFAENNLSIIESYL
                     ESVNPELIILDSIQTVFSPEISSAPGTVSQIKEGTSKFMKISKKMGISTFIVGHVTKE
                     GSLAGPKLLEHMVDTVLYFEGERYNTYRLVRAVKNRFGSTNELGVFEMRDLGLVELDN
                     PSKILISEKPKDVAGSVIISTVEGTRPMLLELQALVSPTSFGIPKRTSTGVDYNRVGM
                     LLAVLEKRVGLQIQNQDVYINIVGGIKINEPSIDLGIAISVASSFRNIPIDEDIAVTG
                     EVGLTGEVRAVSFIEKRIAECKKLGFKKIVVPRSNYDVVKETKGIEIWPVDNLRQAIN
                     IVLGRNQ"
     gene            6239..7309
                     /gene="disA"
                     /locus_tag="PC494_003130"
     CDS             6239..7309
                     /gene="disA"
                     /locus_tag="PC494_003130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA integrity scanning protein DisA"
                     /protein_id="HDF3913609.1"
                     /translation="MENFLDNKNMLYALKMISPGTPLRLGLNNVLRAKTGGLIVIATN
                     EDVMKIVDGGFAINAEYSPSYLYELAKMDGAIVLSGDVKKILFANAQLIPDYFIETSE
                     TGTRHRTAERVAKQTGAIVIGISQRRNVITVYRGNEKYVVEDISKIFTKANQAIQTLE
                     KYKTVLDQAVTNLNALEFNDLVTIYDVALVMQKMEMVMRVTSIIEKYVIELGDEGTLV
                     SMQLEELMGTTRIDQKLIFKDYNKENTEIKELMKKVKNLNSEELIELVNMAKLLGYSG
                     FSESMDMPIKTRGYRILSKIHRLPTAIIENLVNYFENFQQILDASIEELDEVEGIGEI
                     RATYIKNGLIKMKQLVLLDRHI"
     gene            7398..8492
                     /locus_tag="PC494_003131"
     CDS             7398..8492
                     /locus_tag="PC494_003131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIN/TRAM domain-containing protein"
                     /protein_id="HDF3913610.1"
                     /translation="MIRKVTRILFILLGFTIGITTYLTLMKDFEILTFGKETYGYIAA
                     VVAGIIIAILGYLIEPWVVNKVKEIAKIVDKELSKYPQTDILLGSMGLIVGFVIAYLL
                     SGLVNRIPIVGGILSLLLYLFLGYLGMKVALKSKNDLFNIGKLGRLANPIKDKDKDKE
                     NKKEVKAIPPKVLDTSVIIDGRIADICKTGFIEGKLIIPAFVLEELRHIADSSDDLKR
                     VRGRRGLDILNIIQKELNIEVEISERDFDDIAEVDSKLLKLAQVLNGKVVTNDYNLNK
                     VAQFQGVEVLNINELANAIKPVAIPGEDMVVQVVKEGKEAQQGVAYLDDGTMIVVDGG
                     RKYMNETIKVLVTSVLQTPAGRMIFAKPKN"
     gene            8621..10798
                     /locus_tag="PC494_003132"
     CDS             8621..10798
                     /locus_tag="PC494_003132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3913611.1"
                     /translation="MRKKIISFLATFIIILTSASQYSFADDISTRGKVIFIDMNRTSM
                     SNMLRIKSLREELDNRGYIGLMNIRGDKGSDDRRSYASMGAGGRANVANEEDINFESS
                     SKDRNIVFESATGKSAKGINNLTINKSINENLNFGEYGSVLGSLGQSLSDNGLKASVL
                     GNSDIIENGQLIKNRNLCLTAMDEYGRIPNGNVDTINKKDLSMPYGISTDYDKLIVET
                     KEAYKNNDVIFVELGDTYRLDLYKPNLNEKTYESMKDSIEKNIDIYLKNIFSMVEEND
                     TVYIASAFPSDLDYKNKRRLSPIIKLNGEGKGILSSSTTRREGIVTNLDVGVEILDNF
                     NIKNQNMVGRKYELINRDDNKEFLMDEYQKIVSISSIRSTILNGFVSIVFLSWIVAMI
                     AILFRKHISKNYKETTFFILKELLKIGIVMPLSFMITPIMNFKTPLAISLGIIIITLT
                     IYLISKVLIKNDLKNMLFFTGLTIVIMVIDAGFGSYLMKSNVMSYDCIIGARYYGVGN
                     EYQGVAIGSAIFTFAILLTYKNIPKWSIIVFSLVILITSASPIMGANVGSAISECVAF
                     LLFILLIYNVKIDFKKIVLLGIAVVFVLGVFVAIDMILGSNSHLGMFVKEIYFNGPGE
                     IIQTFSRKIEMNLKLAQTSAWVNILLTGIGVILVLMINQIRYFKQLMDEYPIVFKGFI
                     ASIAGCLVTLLVNDSGIVSSATAFIYVIVPMITLSINLTALKE"
     gene            complement(10984..11829)
                     /locus_tag="PC494_003133"
     CDS             complement(10984..11829)
                     /locus_tag="PC494_003133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF3913612.1"
                     /translation="MNRNNFSHEIIEPIDNLDVNFKLFDDSGSYVANHWHNSLEIIYI
                     TSGDLQINMEGYTYNLKANECMFINSGIIHSTRCIYQNTSILLQVPLSFLNKYIPDFK
                     NCYFDFKVNANDNNYKKNSSKVKLILENMREIKLSSPPAANLLFTSLLFELLFELYTN
                     FKISVGNKNMKKTVLDLSKFEPVLEYTKINYKMPISINKIAKVAHLQPEYFCRKFKQY
                     MGQTYLEYLNDVRISHIYKDLINTNDTLCSILEAHGFTNTKLFYRIFKEKFKCTPKHI
                     RKKST"
BASE COUNT         4923 a         1214 c         2127 g         3620 t
ORIGIN      
        1 gaaggtatat ttaaaatata aagtatttaa agttctgaaa tctaatcatg aagcaaaaaa
       61 ttagcatttg gttatcaata aatataataa ataaaaactc ataattaatg aaagaataaa
      121 ttcatatcta aatttctata aaaaatttaa atttatacaa tttagggctt taaaaattta
      181 aataataggt gtaaaataat agtcaaagaa agtcaaaaat aaaaaggtgt gtggtgatat
      241 taatggcaac tatgacagat ataattgaaa aatttattaa agatttgatg gaagaagata
      301 atagcataca aattcaaaga aatgaactag caaacttgtt tagttgtgca ccatcacaaa
      361 taaattatgt cttaacaaca agatttacaa tagatagagg atattacatt gaaagtaaaa
      421 aaggcggcgg aggatatgtt caaatagaaa aaatacgaaa aagtaaagat gggcatatta
      481 gagaactact aaatgaaaaa ataggaagtc agatatccta taaaaaagca aaagaattat
      541 tagaaggttt aaaagagtcg gatttgatta acgaaagaga attaaaatta atattatatg
      601 caatagatga taaatcattg tgtatgccaa tatatgaatt aaaagagaag gtaaggtcta
      661 atattttaaa gaatataata ataggattat ttagtataga ggagtgataa tttatgctat
      721 gtcaaaaatg caataagaat aaagcatctg tatattataa taagatagtc aatggagaaa
      781 aaacagagat gtatttatgt agtgagtgtg caaaagagaa tacagaaatg aattttaact
      841 tagatatgcc tttttcaatg atggatatat tttctaattt aggttttcaa cctaaaaaag
      901 aacttgagga aaagctagtt tgtcctaaat gcaatacaac atatagtgag tttaagaata
      961 atgggagatt tggatgtagt gaatgttata atgcatttag tagtcaagta aatccaatgc
     1021 ttcaaaatat acatgggcat atagaacata caggaaaagc acctaaaaaa tctttttata
     1081 agataagtgt agaaaatgag attaaagaac taaaagaaga tttagataga gctataaaaa
     1141 atgaagagta tgagttagca gctcaattta gagataaaat taaatattta aaaggttcta
     1201 ttgactaaga ttggagtgat attatgaaag agaacatagt catgaaatca agagttaggc
     1261 tagctagaaa tttaaataac tatccatttc caaataaatt agataaagaa tgtgccatgg
     1321 aaataataga aaaagtaaaa aatgcgttta ttaattctaa cttagaacaa aaagaagaat
     1381 ttgatttcta taaaattgaa gatttagacc aatctaaaaa aatgcttatg gttgaagaac
     1441 atataataag cccagattta gcagaaaatg ataaaagtgc agttatagta aaaaaagata
     1501 aaactataag tataatgata aatgaagaag accatataag gatacaaact atatgtgatg
     1561 atttaaactt agaatatgca tatagtgtag caaatgaaat agatgatttg ttagaatcaa
     1621 gtttagaata tgcctttaac acaaagctag gttatctaac atcttgtcca actaatacag
     1681 gaacaggaat gagagcttct gtaatgatgc atttaccagc attaagtcaa ctaggctata
     1741 tggatgaact ttataaaatt tcatcacaaa taggcatagc aattagaggg atatatggag
     1801 aacgaacaga agcattggga aatatatatc aaatatctaa tcaacttaca cttggaagaa
     1861 cagagtctaa tattatagaa aatgtaagtg gacttacaaa agatgcaatt tcaaaagaaa
     1921 taaaagctag agaaatattg caaaaaaaat taggtataaa actagaagat aaaatattta
     1981 gatcgatagg gacacttgaa aattcaagag taatgagtag cgcagaggca atgagccatc
     2041 tatcaaatat aaaaatggga atagaaatga actatataga taaactagat ttaagggcta
     2101 tagaacaact tatgataggt atacaaccag cgcatcagtc aataatgtat aagagtgatg
     2161 atgttgagaa tagagatata aatagagcaa catatattag agaaactttg gaaaaattaa
     2221 gaggagggat gaattgtgaa cttcaataga tttacacaaa gagctaaaaa ggcaattgat
     2281 ttagcgtttg aatctgctaa aagtctagga cacaatattg tcggaagtga acatatactt
     2341 ttaggtcttt taagagaaga agaaggtata gctgctaaag ttctaagtaa agttggattt
     2401 acagaagctt atttagaagg caaaatagtt gatatggaag gtaagggaga agaaatctca
     2461 gaagatatag tattaagtcc aaggagtaaa caaatacttg aattatcagg aatgtttgca
     2521 aataaattaa aaacaaatta tattgggact gagcatatat tattagcaat tattcaagaa
     2581 ggtgaaggaa tagctaataa gattttaaat tatgctggag taaatgatag gactttagcc
     2641 caattaacaa ttgatatgat gggtattagt gataaaaatc aatacaaagc agagaatagt
     2701 tacacgggca accagaatca agcagaatct aaagtacttg ataagtatgg aagaaatctt
     2761 acactatatg caaaacagaa taaaatagac cctgtaatag gtagagaaaa agaaatacaa
     2821 agagtaatac aaatattaag tagaagaact aaaaacaatc cagtgttgat aggagaccca
     2881 ggtgtaggga aaacagccat agctgaaggt ctggctacaa atatagcctt aggaaatgtt
     2941 ccagaaacac taaaaaacaa aactttatac tctttagaga tgggttcatt attggctgga
     3001 gctaagtata gaggagaatt tgaagaaaga attaaagaag ttgtagatga agttgttaaa
     3061 aatggaaaca taatcttatt tatagatgag atgcacacaa taataggggc tgggtctact
     3121 ggagaaggct ctatagatgc ttcaaatata ttaaagccag ccttagcaag aggagaaata
     3181 caagttatag gtgcaactac aattgatgaa tatagaaagc atgttgaaaa agattctgct
     3241 ctagaaagaa gattccaacc agttatggta gatgaaccaa ctaaagagga ctcaataaaa
     3301 atattagaag gattaagaga taaatatgaa gctcatcata aagttaaaat aactgatgat
     3361 gctataaagg cagctgtaga attatcaact agatatatat cagacagata tctgccagat
     3421 aaagctatag acttgattga tgaagctgca tcaaaagtaa gattaaaaga aaatacacct
     3481 ccttcagaaa taaaaaaatt agaactagaa atagaaaata tagataaaga aaaagaagaa
     3541 gcagtaagat gtcaagactt tgagaaagca gccaaaataa gagatgaaca aggtctactt
     3601 aaaaaacaat tagaagatgt tagagaaaga tggaacaagt catctaaaca ttcagattta
     3661 gttgatggag aagttattgc tgaagtagtg ggcttatgga caggaatacc agttaataaa
     3721 attcttgaag aagaggctga tagacttttg agacttgagg aaatactgca caatagagtt
     3781 ataggtcaag aacaagcagt aaaatctatt tcaaaggcaa tcagaaggtc aagagcaggt
     3841 cttaaagacc ctaatagacc aattggttca tttttatttt taggtccaac aggagtaggt
     3901 aaaacagaat tatctaaggc attagcagaa gtgcaatttg gagatgaaaa tcaaataatt
     3961 agaatagata tgtctgaata tatggaaaaa catgctgtgt caagaatgat aggttcacct
     4021 ccaggttatg taggtcatga tgaaggtggt caattaactg aaaaagtaag aagaaatcca
     4081 tattcagtta tcttatttga tgagatagaa aaagctcatc cagatgtatt taatattctg
     4141 ttacaaattc tagatgatgg tagactaact gattcaaaag gaagaactgt agattttaag
     4201 aatactattg taataatgac atcaaatgtt ggagcatcta caattggtag acaaaaaact
     4261 ttaggattta gtatagctaa aggagacgaa gaagaaaaat ctcaatatga aaaaatgaaa
     4321 gaaaatataa tgggtgaatt aaaacaaaga ttcagaccag agtttttaaa cagaatagat
     4381 gatataattg ttttccactc actaaatgaa aatcatatat caaaaatagt acttttaatg
     4441 gcagcgaaac tacaagagag attaaaagaa atggatataa aattagaaat gagtgatgag
     4501 gctgttaaat taatttctaa atctggattt gacttagaat atggagcaag acctcttaaa
     4561 agagctttac aaaaagagtt ggaagatgag ctatctgaag caatcttaaa aggtaatgtg
     4621 aaaaagggaa gtaatgtagt agcaaaagtc aaagatgaaa aaatagtttt tgaaactaaa
     4681 taatttaata gagttgcatt ttaaaatatt gcaaatataa gttttataat ctaaacaaaa
     4741 ttttaagggc aatgaatcta taataattca ttgtccttaa ttattttatt taatctttac
     4801 atattgtctt tcagatatgc taaaattata gtatagaata aaaaattaag gatgataaaa
     4861 gtatggcaaa aataaaaaca aaatatgtat gtcaatcttg cggatatgaa acagctaaat
     4921 ggcttggtaa atgtccagaa tgtacaaaat ggaatacatt tgtagaagaa atagaccaaa
     4981 aaagcaccaa aaaagaggtc tttataatag ataaatcttc atctaaacca gtcagtataa
     5041 actcaataga gagtaaagaa gaagagcggt ttacaacaga tataaatgaa ttagatagag
     5101 tgcttggagg aggtatagtt aaaggctctt tagtgcttgt tggtggtgac cctggtatag
     5161 gtaaatcaac acttttaatc caagtatcta gtaatgttgc caatttagga aaaactgttt
     5221 tatatataac tggagaagaa tcagaatctc aaataaaaat gagagctaaa agattaggta
     5281 ttaactcaga aaatttatat atatttgctg aaaataattt aagtataatt gaatcttatt
     5341 tagaaagtgt aaatccagaa ttaataattc tagactcaat tcaaactgtc ttcagtccag
     5401 aaatatcctc ggcaccagga actgtcagcc aaattaaaga aggtacttca aaattcatga
     5461 aaatttctaa aaaaatggga atttcaacgt tcatagttgg gcatgttaca aaagaaggtt
     5521 cactagcagg accaaaatta ttagagcata tggttgatac tgttctatat tttgaaggag
     5581 aaagatataa tacttataga ttagtaagag ctgttaaaaa tcgatttggt tcaactaatg
     5641 aacttggagt gtttgaaatg agggatttag gattagtaga acttgataat ccatctaaaa
     5701 ttttaatctc tgaaaaacca aaagatgtag caggttcagt aataatatct actgtagaag
     5761 gtacgagacc aatgttactt gaattgcaag cattagtttc tcctacaagt tttggtatac
     5821 caaaaagaac atctacagga gtcgattaca atagagtagg tatgttatta gcagtattag
     5881 aaaaacgtgt tggtttgcaa atacaaaatc aagatgtcta tataaacata gttggaggaa
     5941 taaagataaa tgaaccctca attgatttag ggatagccat ttctgtagca tctagtttta
     6001 gaaatatacc gatagatgaa gatatagctg ttacaggaga agtgggactt acaggagaag
     6061 ttagagcagt aagctttata gaaaaaagaa tagctgagtg taaaaaactt ggatttaaaa
     6121 agatagtagt tcctagaagt aattatgatg ttgtaaaaga gaccaaaggc atagaaatat
     6181 ggccagtaga taacttaaga caagctataa atatagtact tgggaggaat caataaatat
     6241 ggagaatttt ctagataata aaaatatgct atatgcatta aaaatgatat ctcctggaac
     6301 tccacttaga ttaggtctaa acaatgtact aagagctaag actggtggat taattgtaat
     6361 tgcaacaaac gaagatgtaa tgaaaatagt agatggagga tttgctataa atgcagaata
     6421 ttcaccatca tatctatatg aattagctaa aatggatgga gctatagttt taagtggtga
     6481 tgtaaagaaa atattatttg ctaatgcaca acttatacct gactatttta tagaaacatc
     6541 agagacagga acaagacata gaacagcaga aagagtagca aaacaaactg gtgctatagt
     6601 cataggaatt tcacaaagaa gaaatgttat aacagtttat agaggaaatg agaagtatgt
     6661 agtcgaagat atatctaaga tatttactaa ggcaaatcag gctatacaaa ctctggaaaa
     6721 atataagaca gtattggacc aagctgtaac aaatttaaat gccttagagt ttaatgattt
     6781 ggtaactatt tatgatgttg cattagtcat gcaaaagatg gaaatggtaa tgagagttac
     6841 aagtataatt gaaaaatatg tgatagaatt gggtgatgaa ggaactttag taagtatgca
     6901 attagaagaa ttaatgggta caaccagaat agaccagaaa ttaatattca aagattataa
     6961 taaagaaaac acagaaataa aagaacttat gaaaaaggtc aaaaatttaa attcagaaga
     7021 actaatagaa ttggttaata tggcaaaact attagggtat agtggttttt cagaaagtat
     7081 ggatatgcct ataaaaacaa gaggttatag gattcttagc aaaatacata gactaccaac
     7141 agcaataata gaaaacttag taaattattt tgaaaacttt caacaaattt tagatgcatc
     7201 tattgaagaa ttagatgagg ttgaaggaat aggtgaaata agagcaacat atataaaaaa
     7261 tggactcata aaaatgaaac aattagtctt attagataga cacatatgat gaattttaaa
     7321 tgaattttac tacttttttc ttgaatataa tatacacttt ggtctataat agataagtat
     7381 aactaggggg tgaagcattg ataaggaaag taacaagaat attgtttatt ttacttggat
     7441 ttacaatagg tataacaacc tatttaacat taatgaaaga ttttgaaata ttaacatttg
     7501 gaaaagaaac atatggttat atcgcagctg tagtagcagg tataataata gccattttag
     7561 gatatcttat agaaccatgg gttgtaaata aagtaaaaga aattgctaaa atagtggata
     7621 aagaattgtc aaaatatcct cagactgata tattgttagg gtctatgggt cttatagtag
     7681 gatttgttat tgcgtattta ttaagtggat tagtaaatag aataccaata gtaggtggaa
     7741 tactatcctt actattatat ttattcctag gatatcttgg aatgaaagtt gcgcttaaaa
     7801 gtaaaaatga tttatttaat attggaaaac taggaagatt agcaaatcct attaaggata
     7861 aagataagga taaagaaaat aaaaaagaag taaaagccat tcctccaaaa gtattagata
     7921 caagtgtaat aattgatgga agaatagctg atatttgtaa gactgggttt atagaaggaa
     7981 aacttattat tcctgctttt gttttggagg aactaagaca tattgcagat tcttcagatg
     8041 atttaaaaag agtaagaggt agaagaggtc tggatatatt aaatataatt cagaaagaat
     8101 taaatataga agttgaaata agtgagagag actttgatga tatagcagaa gttgatagta
     8161 aattattaaa gcttgctcag gttttaaatg gaaaagttgt tacaaatgat tataacttaa
     8221 ataaagttgc tcaattccaa ggtgttgaag tattaaatat aaatgagtta gctaatgcta
     8281 taaaaccagt tgctatacca ggtgaagata tggttgttca agtggttaaa gaaggaaaag
     8341 aggctcaaca aggtgttgca tatctagatg atggaactat gatagttgtt gatggaggaa
     8401 gaaaatatat gaatgagact ataaaagtac tcgttacttc tgttcttcaa actcctgcag
     8461 gtagaatgat atttgcaaaa cctaaaaatt aatatgttca aagaaaccta taatttgggc
     8521 tgtttatttt aaatagatgg tccaaattta tttatttata acgataatgt ttaatgtatt
     8581 cttaaagatg gggatttaaa tcagaaagca gggagaattt atgagaaaaa agattatatc
     8641 tttcttagca acatttatca taatattaac atcagcaagt cagtatagtt ttgcagatga
     8701 tatatcaaca cgtggaaaag taatatttat agatatgaat agaactagta tgagtaatat
     8761 gttaagaata aaatcattaa gagaagaact agacaataga gggtatattg gcttgatgaa
     8821 tataagaggc gataaaggaa gtgatgatag aaggtcatat gctagtatgg gtgctggtgg
     8881 tagagctaat gtggctaatg aagaagatat taattttgaa agctcgagta aggatagaaa
     8941 tatagttttt gaatcagcta caggaaaaag tgcaaaaggt ataaataatt taactataaa
     9001 taagtctata aatgaaaatt taaactttgg agagtatggt tctgtattag ggtcattagg
     9061 acaaagttta tctgataatg gattaaaagc atctgtattg ggtaattcag atataattga
     9121 aaatggtcaa cttataaaaa atagaaactt atgtctaact gcaatggatg aatatggaag
     9181 aatacctaat ggaaatgtag atactataaa taaaaaagac ttatctatgc cttatggaat
     9241 atcaactgat tatgataaat tgattgtaga gactaaagaa gcttacaaaa ataatgatgt
     9301 gatttttgtg gagcttggag acacatatag attagattta tataaaccaa atttaaatga
     9361 aaaaacatat gagagtatga aagatagcat agaaaaaaat atagatatat atttaaaaaa
     9421 tatattttct atggttgaag aaaatgacac tgtctacata gcaagtgcat ttccaagtga
     9481 tttagattat aaaaataaaa gaagactttc tccaataata aaattaaatg gagaagggaa
     9541 aggtatatta tcatcttcaa ctactagaag agaaggtatt gtaacaaatt tagatgttgg
     9601 ggttgaaata ttagacaact ttaatataaa aaatcaaaat atggttggaa gaaaatatga
     9661 acttattaac agagatgata ataaagaatt tttgatggat gaatatcaaa agatagtatc
     9721 tatttcaagc ataaggtcta caatactgaa tggttttgta agtatagttt tcttgtcatg
     9781 gatagttgct atgattgcaa ttttatttag aaagcatata tcaaaaaatt ataaagaaac
     9841 aacatttttt atattaaagg aacttttaaa aataggaata gtaatgccac tgtcatttat
     9901 gataacacca ataatgaatt tcaaaacacc attagcaata tctttaggaa taattataat
     9961 aacacttact atatatctta taagtaaagt tttaataaag aacgatttaa aaaacatgct
    10021 gttttttact ggattaacca tagtaattat ggttattgat gctgggtttg gctcatattt
    10081 aatgaaaagc aatgttatga gttatgattg tataattgga gctagatatt atggagtagg
    10141 aaatgagtat caaggtgtgg caatcggtag tgcaatattt acatttgcaa ttttacttac
    10201 atataaaaat ataccaaagt ggtctataat agttttttct ttggttatct taattacaag
    10261 tgcatctcca attatgggag caaatgttgg aagtgctatt tctgaatgtg ttgcattttt
    10321 actatttata ctattgatat ataatgtaaa gatagatttc aaaaaaatcg tattattagg
    10381 tatagcagta gtatttgtat taggagtttt tgtagcaata gatatgattt tgggaagtaa
    10441 ttcacattta ggcatgtttg taaaagaaat ttactttaat ggaccaggag aaataataca
    10501 aacatttagt agaaagatag agatgaattt aaagctagct caaaccagtg catgggtaaa
    10561 tatactgtta actggaatag gtgtaatttt agttcttatg attaatcaga ttagatactt
    10621 taagcaactg atggatgagt atccaattgt atttaaagga tttatagcat caatagcagg
    10681 atgtttagta actcttttag tgaatgactc tgggattgtg tcatcagcta cagcctttat
    10741 ttatgtaatt gtacctatga taacattaag tataaatctc acagcattaa aagaataagt
    10801 actgtatgaa taatatgtaa atattaatac attaatttaa cttctttatt tacaaaataa
    10861 agaagaaagt ttataaaaaa taaattataa taaaaaagag tttatctcaa aattgattat
    10921 tctaatcaaa ttttaagata aacttttttt attataaaga taaataacat ataacctcat
    10981 attttaggta gatttttttc ttatatgttt aggagtgcat ttaaattttt ccttaaaaat
    11041 tctgtaaaat aattttgtat tagtaaatcc atgagcttct aatatactgc ataaggtatc
    11101 atttgtgtta attaaatctt tataaatatg agaaatacgc acatcattta aatactctaa
    11161 gtaagtttgt cccatatact gtttaaattt tctacaaaaa tattctggtt gtaagtgtgc
    11221 taccttagcg attttgttaa tagaaatagg cattttgtaa ttaatctttg tatattctaa
    11281 aactggttca aattttgaca aatcaagtac tgtttttttc atatttttat tacctacaga
    11341 tattttaaag tttgtatata attcaaataa aagttcaaat aataagcttg taaagagcag
    11401 attagctgca ggaggagaac taagtttaat ttctctcatg ttttctaata taagtttaac
    11461 tttacttgaa ttttttttat agttattgtc attggcatta accttaaagt caaaatagca
    11521 atttttaaaa tcagggatat atttgtttag aaaagacaat ggtacttgca ataatataga
    11581 ggtattttga taaatacatc tagttgagtg aataattcca gaattaatga acatacactc
    11641 attagctttt aaattataag tgtaaccctc catgttaatt tgtaaatcac cagaagttat
    11701 ataaattatt tctaatgagt tatgccaatg atttgctaca taactaccac tatcatcaaa
    11761 tagtttgaaa ttaacatcta aattatcaat aggttcaatt atttcatgtg aaaaattatt
    11821 tctgttcata ataatatcct ccttataatt ttaaattata aatagtaaat ttataatgtt
    11881 caat
//
LOCUS       DAMKNB010000100        11828 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.106, whole genome shotgun sequence.
ACCESSION   DAMKNB010000100 DAMKNB010000000
VERSION     DAMKNB010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 11828)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11828)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11828
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.106"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            190..1230
                     /locus_tag="PC494_003134"
     CDS             190..1230
                     /locus_tag="PC494_003134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDF3913613.1"
                     /translation="MDKHSDSVMYGGMEVYNIWGTTTVDSIIGESDVMRALKNRICKI
                     GNSDSTVAITGESGTGKELIARAIHLAGNRGNKTFVAINCAAIPEPLLESELFGYTKG
                     AFSGADSKGKIGKFELANGGVVFLDEIGDMPIQLQSKLLRVLQEKKFTRIGSNELIDI
                     DVRIISATNRDLFELVKENKFREDLYYRLNVIPLEVPPLRERGDDIQILINNFIDKYS
                     RKMKKNVYHIEPDVEQMLLKYPWPGNIRELENTIELALNLLEEDGIIHKGIINRKILE
                     YFKLNNINIKLLEESDYEISMEQDILTLEEFERAYIKKVLKFYGNDTKSKKLAAKKLG
                     ISLATLYRKIDV"
     gene            1558..2904
                     /locus_tag="PC494_003135"
     CDS             1558..2904
                     /locus_tag="PC494_003135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HDF3913614.1"
                     /translation="MSKYQKNVSMFDIDGRPPILKCLPLSMQHILAMIVGTVTVPIVV
                     GGAVGVSPTQITLLVQYALIIAGISTLIQLYPIGNIGSRLPIIFGVGFTYVPTLVAVG
                     GNYGLASILGAQLIGGVATVLIGIFIKKIRKFFPNIVAGTVVFTIGLSLYPIAINYMA
                     GGVNSPTYASMQNWAVAAITLVVVIGLSQFAKGYAKLAAIFLGIIVGYCVSLVLGIIN
                     FDPIREATWFAIPKPLEFGMEFDMPVIISVVIVSIINAVQAIGDLSATTMGGMDRNIT
                     DKELSSGVIGSGICTMIGALFGGLPSSYSQNVGMVAMNKVISRFVLGIAGIFMLLSGF
                     VPKFGALMTTIPYSVLGGATISIFSMITMTGIKLIITEELSSRNITIVGLAIALGMGI
                     TSVPAAQEAFPSFVKLVFGESPIVIATLVAFVLNLIIPNKSLEDEAKERAVMEETN"
     gene            3201..4562
                     /locus_tag="PC494_003136"
     CDS             3201..4562
                     /locus_tag="PC494_003136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine/pyrimidine permease"
                     /protein_id="HDF3913615.1"
                     /translation="MKTRNTSKYDVDGIPPLKESIPLALQHLLAMIVGNMVPAILIAN
                     VVGLNQGQATMLIQGSMLAAGLATFLQLYPIPLFKGFKLGSRLPVMMGMSYVFLGACL
                     SVAAKDGLAALFGAQIAAGVIVFFVGFGVKKIRHIFTPIVSGTIIACMGLGLFATAIK
                     NLAGGEGTQTFGSPINFTVGVIVAFVIIMINKYGKGLVKNSSILIGILVGYAISLVLG
                     LVDFSAVQGAAIVSLPTPAAFGLEFRPELIVMFTIIYIIGIADMMGACTIATVGAMDR
                     EVTDEELASVVLGNSITSIISSLFAALPTGVFSQNTVIVSMNKVTSRFVIALGALVLL
                     LAGISPALGAIMTTIPSCVVGGATLVVFSSIAMSGFSIMSMDGFTEENNLIAGVSIAT
                     SMGLTTAPQVLDQFPETIGTVLGGSSIVSGAIIAILLQTLFKLKSRKSAENVTSNLEE
                     NIG"
     gene            4635..6029
                     /locus_tag="PC494_003137"
     CDS             4635..6029
                     /locus_tag="PC494_003137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HDF3913616.1"
                     /translation="MIDILIKNAIIVTVNKDRDVIFDGAIAIQGDRILDIGNTVDIEP
                     KYLDAKKVIDANGKVIFPGFINTHNHLFQVLLKGLGDDMALHEWLNTMMFPSAKFLTE
                     QDTYDAAMLGCMEGLKSGITTMVDYMHTHNRPGLTDGIVKAYKDLGIRGVVGRGCIDL
                     GIHKELIEDVETVEKDLRRVFEKYHNSENGRIKICVAPSSMWAISEEMGKMLWNIVKE
                     YDSYFTVHISETEFARTATKDIHGEIDIKLLEKWGIVGPEVVAVHCVCITDEDMEMLK
                     KYDIKVSHNVASNMYLASGVAPVPEMLKKGINVSLGLDGAASNNAQDMVELMKLTALQ
                     HKVNNCDPLAISAEKVLEMATIEGARTLRMEDEIGSLEIGKKADLVIFNSMLSPKSIP
                     LHNPVSTLVYSASMHNVESVLVDGNVILENGKVTTIESEEQVLLNAQHAAEELCKRAN
                     VTNRMEGHKWNSLY"
     gene            6091..6561
                     /locus_tag="PC494_003138"
     CDS             6091..6561
                     /locus_tag="PC494_003138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(2Fe-2S)-binding protein"
                     /protein_id="HDF3913617.1"
                     /translation="MEKIKLNINDYMYEIEVEKNETLLHVLREKLNLTGAKQGCNSGS
                     CGACKVLIDGVDMKSCKLLAKNCEGKVIYTIESFANGENLHPIQEAFIEVGAVQCGYC
                     TPGMIITTQALLNRNASPNEDEIREAFKENLCRCTGYVKIIEAVKLSAARLGGR"
     gene            6564..8780
                     /locus_tag="PC494_003139"
     CDS             6564..8780
                     /locus_tag="PC494_003139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-dependent oxidoreductase"
                     /protein_id="HDF3913618.1"
                     /translation="MEKVIGKSYPLKDAALKVTGQMKYVADMKPQNVLYAKMLLSPVA
                     HAKIKSIDTSEAEKVVGVRAIATYLNTSQRKYNGSLRFYEHKIPENEVIFSDTVRFVG
                     DRVAAVAAETPEIAEKAVKLIKVEYEELPAVFTIQDAIKEDAICIHGDSNIVSQNNIN
                     GGDVEKGFKECDYIFEDEYSTPAIHHSAIETHSVIAHYDYNDKLTVHTPCQNTFGFRI
                     ILSQIFGMSLNKVRVIRPAIGGSFGGKLELTIEPVAAALSKMTRRPVKMVLTRKESMI
                     STRTRHGSFVKLKTGVNKDGEVIAQDIKIYTNTGAYASSALNVIGALSHKVFKVYKIP
                     NIKFTGMPVYTNTPIAGAMRGYGSPQIFMAQQAQFAKIAKEIGMDLVDFQNKNAVEPD
                     DVDIIFHGSLGNPRVLDCIEQGKKMFKWDEKKKLPKEEGKYLRGIGMAIGAHGNGVFG
                     AHRDVVTLTLKLNEDGTLTLLTGAHDMGNGVVTMQTMMVAEVLGITPDKVDTFETDTD
                     ACTFNLGDYASRGVFVEGGGAKKTAEKLKNLILEEAEKLLETSKEDLYLDNGCVISKL
                     DENVKASLSDVAVYSQSKSLRELTVVEDYSSPAGRTSYGVHFAEVLVDKETKDIKVVD
                     FVAVHDVGRVINPLNLEGQLEGGIHMGLGYALSEELAFDEQGRPKATDFKTYKLFRTV
                     DMPKCQVAFVDGYEKAGPFGGKSIGECAVVPVAPAVANAVYNATDVEIHSLPIKLK"
     gene            8863..9534
                     /locus_tag="PC494_003140"
     CDS             8863..9534
                     /locus_tag="PC494_003140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HDF3913619.1"
                     /translation="MAKILGICGSPRKGATEYAVLEALKEAETIPGIETEYWSVRGKK
                     ISPCVHCDACIRKETMCIIKDDIQELEQKILEADGIIVGSPVYDMNITAQLTAVFNRL
                     RPMYLVHPGKLQNKVGAAITTGGTRYGGQELTKLPIINFFLMHEMLVSGGLGGCYIGG
                     TIWSKDGKAKGAQEDETGMDTVKRLGKGAAEAVMVSKFGLEKWNVVKEELDVKKDEKS
                     PLRDH"
     gene            9897..11111
                     /gene="dpaL"
                     /locus_tag="PC494_003141"
     CDS             9897..11111
                     /gene="dpaL"
                     /locus_tag="PC494_003141"
                     /EC_number="4.3.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopropionate ammonia-lyase"
                     /protein_id="HDF3913620.1"
                     /translation="MLKEIKWKVNNLPKGDKENCIKFLNEEEITKVRNFHKSFPQYKE
                     TPLANLEGLAKKLGVAGVYVKDESYRFGLNAFKVLGGSYSMGRYLAQRLDTDISELGY
                     DKLTSKEIKEKLGEITFFTATDGNHGRGVAWTANKLGQKSVVLMPKGSSEFRLNKIKG
                     EGADASITDLNYDDAVRLANDYAEADDHGVMVQDTAWDGYEEIPAWIMQGYGTMAQEA
                     IEQLKEYGVDRPTHVFVQAGVGSLAGAVQGYVASIYDECPITVVVEADEADCYYKSAE
                     AGDGKPRFVGGDMPTIMAGLACGEPNTIGFEVLKNHAAAFVSAPDWVSAKGMRTLGNP
                     LNGDEKVISGESGAVTTGLLVAAMEREDLADLRKDLKLDENSRILLISTEGDTDPDKY
                     RSIVWDGEYPSI"
     gene            11238..>11828
                     /locus_tag="PC494_003142"
     CDS             11238..>11828
                     /locus_tag="PC494_003142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HDF3913621.1"
                     /translation="MLNEQRKQEVTEICQKLIQNPSSSGNEEGVVKAIEESFEKLGFD
                     SWSRDRYGNIVGCIKGNKPGKKILFDGHIDTVPVPDASKWSVPPFEGKIVDGKIYGRG
                     TSDMKGQYTAMMSAVAYFAKDTNRDFAGELYVAGVVHEEIFEGVSAREISKAVQPDYV
                     VIGESSELNLKIGQRGRGEIVVETFGKPAHSANPEKG"
BASE COUNT         4472 a         1359 c         2399 g         3598 t
ORIGIN      
        1 tttaatagag catttttgta aaatgaagaa agtatatcta tcaaattaaa actaagtaga
       61 tatacttttt attaagtttt gttttaaaat aatattatta aattataact aagcttttct
      121 gttatgatat aattaaatag ataatgtgaa tgattattat atagaatact tatttggagt
      181 tgatatttta tggacaaaca cagtgattca gtaatgtatg gtggaatgga agtatataat
      241 atttggggaa caacaacagt agactccata attggagagt ctgatgtaat gcgtgctctt
      301 aagaatagaa tttgtaaaat tggaaatagt gattctactg tagctataac tggagaaagt
      361 ggcactggaa aagaattaat agcaagagcc attcatctcg caggaaacag agggaataaa
      421 acattcgttg ctataaactg tgctgctata ccagaacctt tactagaaag tgaacttttt
      481 ggatatacaa aaggagcttt tagtggagca gattcaaaag gtaaaattgg taagtttgaa
      541 ttggccaatg gaggggttgt atttttagat gagataggag atatgccaat tcaactacaa
      601 tcaaagttat tgagggtatt acaggaaaag aagtttacga gaataggttc aaatgaacta
      661 attgatatag atgttagaat catatcagct actaatagag atttatttga gttggttaag
      721 gaaaataaat ttagagaaga cttatactat agattgaatg taataccttt agaagtgcct
      781 ccacttagag aaagaggaga cgatatacaa atattaataa acaattttat agacaaatat
      841 tcgagaaaga tgaagaaaaa cgtgtaccat atagagccag atgtggaaca aatgttgctt
      901 aagtatcctt ggccaggaaa tattagagag ttggaaaata ctatagaact ggcattaaac
      961 cttcttgagg aagatggaat aatacataaa ggaataataa atagaaagat acttgaatat
     1021 tttaagttaa ataatataaa tataaagtta cttgaggaaa gtgactatga gataagtatg
     1081 gaacaagaca tacttacact tgaagagttt gaaagagcct atataaagaa agtgttaaag
     1141 ttttacggaa atgatactaa gtctaaaaaa ctggctgcca aaaaacttgg aatatcacta
     1201 gctacattgt acagaaaaat agatgtataa taattaggct ttttattctc aattctaaaa
     1261 tttgaaatta taaaattgat aaaaaacact tggaaaacta ttttctaagt gtttttttgt
     1321 gtaatagcat tttattatcc aaaaataaaa aaaatttaaa agaatttaaa aaaataaatg
     1381 ctttaataaa ttatcaaata ctaacaaata taataaaaat tatatatgta aaacaattat
     1441 gttaaaaaat tggcattata attgcttcat attaagttga gatgacaaaa taaaaaaaga
     1501 aaggatgttg tgtgagataa taataactgt cattaaaaat agttgggagt gataaccttg
     1561 agtaaatatc aaaagaatgt ttctatgttt gatattgatg gaaggccacc aattttaaag
     1621 tgtttgccac tatcaatgca acatatacta gcaatgatag ttggaactgt tacagtacct
     1681 atagtcgtag gaggagctgt gggtgttagc cctacacaaa taacactttt agtgcaatat
     1741 gcattaataa tagctggtat atcaacactt atacaactat atccaatagg aaatattggt
     1801 tcaagattgc ctataatttt tggagttggt tttacttatg taccaacact tgtagcagtc
     1861 ggaggaaatt atggattagc aagcattttg ggtgcacaat taataggggg agtggctaca
     1921 gtattaatag ggatattcat aaaaaagata agaaaatttt ttccgaatat agttgcagga
     1981 acagtggttt ttacaattgg attatctttg tatcctatag caataaatta tatggcaggt
     2041 ggtgtaaata gtcctactta tgcctctatg caaaactggg cagtagcggc tataacatta
     2101 gtggtagtta taggtcttag tcaatttgca aaaggatatg caaaattggc agcaatattt
     2161 ttgggaatta tagttggata ttgtgtatct ttagttctgg gtataataaa ttttgaccct
     2221 attagagagg caacttggtt tgcgatacct aaaccgcttg aatttgggat ggaatttgat
     2281 atgcctgtaa taatctcagt agtaattgta agtataatca atgctgttca agcaattgga
     2341 gacttatcag ctactacaat gggaggcatg gataggaata tcacagataa ggaattatca
     2401 agtggagtaa taggaagtgg aatttgtact atgataggag ctttgtttgg aggtttacca
     2461 tcatcatata gccaaaacgt ggggatggta gctatgaaca aagtaataag tagatttgtg
     2521 cttggaatag ctggtatatt tatgttattg tcggggtttg tgcctaaatt tggtgcatta
     2581 atgactacta taccatattc tgttttagga ggagctacaa tatctatatt tagtatgata
     2641 acaatgacag gtataaagtt aattattaca gaagagttgt catcaagaaa tattaccatt
     2701 gttggtttgg caattgcctt aggcatggga ataacatcag tcccagcagc ccaagaggca
     2761 tttccttcat ttgtaaagtt agtatttgga gaatctccaa tagtaattgc aacattggtt
     2821 gcattcgttt taaatctaat aataccaaat aaaagtctag aggatgaggc taaagaaaga
     2881 gctgttatgg aagagactaa ttaagatata ataatttaaa agaattgttt aaattattta
     2941 gtatgagatt gttagattat ttttgatagc tattcatttt aataaaaaat ttaacaaata
     3001 aatatatacc aggcaattaa tgttcattta agttgaaaat cggggaggca atatttagaa
     3061 atttgttaat tttttataaa aatagctcag tttagctgtg tttatcggtt gagcaataaa
     3121 ttcatggtca taaaaatatt tatagaaaat aattataaaa atatttagtc aagatattta
     3181 tgtatgggag gatttatttt atgaaaacac gtaatacttc aaaatatgat gtcgatggga
     3241 taccaccact aaaggaatca atacctttgg ccttacaaca tctgttagca atgatagtag
     3301 gaaatatggt acctgcgata ttaatagcaa acgtggtagg acttaaccag gggcaagcaa
     3361 caatgttgat tcagggttct atgttagcag caggtttagc aacgttttta cagttatatc
     3421 caataccttt atttaaagga tttaagttag gttcaagatt acctgtaatg atgggaatga
     3481 gttatgtatt tttaggagct tgtctttcag tagcagctaa agatggttta gcagctctat
     3541 ttggagcaca gattgctgct ggggtaatcg tattctttgt aggatttgga gttaagaaaa
     3601 ttagacatat attcactcca atagtttctg gaactataat agcatgtatg ggacttggac
     3661 tattcgcaac agctataaag aatttagctg gaggagaagg cacacaaaca tttggaagcc
     3721 caataaactt cacagtagga gttatagttg cttttgtaat aataatgata aataaatacg
     3781 gtaaaggttt agtaaaaaat tcttcaatat taataggaat attagtaggt tatgctatat
     3841 ctttagtttt aggattggtt gatttctcag ccgttcaagg agcagctata gtatctttac
     3901 caacaccagc agcttttgga ttagaattta gaccagagtt aatagtaatg tttactatta
     3961 tttacataat aggtatagct gatatgatgg gtgcctgtac aatagctaca gtaggagcaa
     4021 tggatagaga ggtaactgac gaagaattag catcagttgt attaggaaat tctataactt
     4081 ctataatttc atcactattt gcagctcttc caactggagt atttagccaa aatacagtaa
     4141 ttgtatctat gaacaaagtt acaagtagat ttgtaatagc actaggggca cttgtattat
     4201 tactagcagg gatatctcca gcattgggtg caataatgac aactatacca tcttgtgttg
     4261 ttggtggagc aactttagta gttttctcat caatagcaat gtctggtttc tctattatga
     4321 gtatggatgg attcactgaa gaaaacaatc ttatagcagg tgtatctata gcaacaagta
     4381 tgggtcttac aactgctcca caagttttag accaattccc agaaacaatt ggaactgtcc
     4441 ttggagggtc aagtatagtt tctggagcaa taatagctat attacttcaa acattattta
     4501 aattaaagtc acgtaaaagt gctgaaaacg ttacttcaaa tcttgaggaa aatattggat
     4561 aaatgtatta gatataatat gagaaaacca tatggtaaaa tgttgtaatg aaagtattca
     4621 aagggggatt taagatgatt gatatactaa taaaaaatgc aataattgtt acagttaata
     4681 aagacagaga tgttatattt gatggagcaa tagctattca aggtgacaga atcttggaca
     4741 taggaaatac agttgatatt gagcctaagt atcttgatgc taaaaaagtt atagatgcta
     4801 atggaaaagt aatattccct ggctttataa atactcataa tcacctgttc caagtgttat
     4861 taaaaggttt aggtgatgat atggcacttc atgagtggtt aaatacaatg atgtttccat
     4921 cagcaaaatt cttaacagaa caagatactt atgatgctgc aatgcttgga tgtatggaag
     4981 gtttaaaaag tggtataact acaatggttg attatatgca tactcacaat agaccaggac
     5041 ttacagatgg aatagtaaag gcatataaag atttaggtat aagaggggtt gtaggtagag
     5101 gttgtataga tttaggtatt cacaaagagc ttatagaaga tgtggaaacg gttgaaaaag
     5161 atttgagaag ggtattcgaa aaatatcata attcagaaaa tggaagaata aaaatctgcg
     5221 tagctccttc ttcaatgtgg gctatatctg aagaaatggg taagatgctt tggaatatag
     5281 ttaaagaata tgattcatat tttacagttc atatatctga aacagaattt gcaagaacag
     5341 caacaaagga tatacatgga gaaatagata taaaattact tgaaaaatgg ggtatagtag
     5401 gtccagaagt tgtagcagta cattgtgtat gtataactga tgaagacatg gaaatgctta
     5461 aaaagtatga cataaaagtt tctcataatg tagcaagtaa catgtatctt gcttctggtg
     5521 ttgcacctgt gccagaaatg ttaaaaaaag gtataaatgt gagtttaggt cttgacggtg
     5581 cagcaagtaa taacgcacaa gatatggtag agcttatgaa attaacagct ttacaacaca
     5641 aagtaaataa ttgtgaccct ctggcaattt ctgcagagaa agttcttgaa atggctacaa
     5701 ttgagggagc aagaactctt agaatggaag atgaaatagg ttctttggag attgggaaaa
     5761 aagctgacct agtaatattt aactcaatgc tttctccaaa atcaatacct cttcacaatc
     5821 ctgtatcaac tttggtatac tcagctagta tgcacaatgt agagagtgtt ttagttgatg
     5881 gaaatgtaat acttgaaaat ggaaaagtaa ctacaattga aagtgaagaa caagtgttgc
     5941 ttaatgcaca acatgcagca gaagaattat gtaagagagc taatgtaact aatagaatgg
     6001 aaggacataa gtggaatagc ttatactaat attaaaataa gattgtaata atattctatt
     6061 acaacattag tttatctgta ggaggagaaa atggaaaaaa taaaattaaa tattaatgat
     6121 tacatgtatg aaatagaagt tgaaaagaat gaaactcttt tgcatgtact tcgtgaaaaa
     6181 ttaaatctaa ctggagcgaa acaaggttgt aatagtggca gttgtggagc atgtaaagtt
     6241 ttgatagatg gagttgacat gaaatcttgt aaacttcttg caaaaaactg cgaaggtaaa
     6301 gttatataca ctatagaaag ttttgctaat ggagaaaatc ttcatccaat acaagaagct
     6361 tttatagaag tcggagctgt acaatgtgga tattgtactc ctggtatgat tataacaaca
     6421 caagctcttt taaatagaaa tgcatctcct aatgaagatg aaattagaga agcttttaaa
     6481 gaaaatctct gtagatgcac aggatatgta aagattatag aagctgtaaa attatctgca
     6541 gctagattag ggggtagata attatggaaa aggtaatagg aaaatcatac cctctaaaag
     6601 atgcagcttt aaaagttact ggtcaaatga aatacgtggc tgatatgaaa ccacaaaatg
     6661 tactttacgc taagatgctt ttaagccctg tagcacatgc aaaaataaaa agtatagata
     6721 caagtgaagc tgagaaagta gtaggtgtta gagctatagc tacttatctc aatacatcac
     6781 aaagaaaata caatggttca ttaagatttt atgagcacaa aatacctgaa aatgaagtta
     6841 tattttcaga tacagttaga tttgttggtg accgtgttgc agcagtagct gcagagactc
     6901 cagaaatagc agagaaagct gtaaaactta taaaagttga atatgaagaa ttgccagctg
     6961 tatttactat acaagatgca ataaaagaag atgctatctg catacatgga gattcaaata
     7021 tagtttctca aaacaacata aatgggggag atgtagaaaa aggcttcaag gaatgtgatt
     7081 atatatttga agatgaatac tctactccag caatacatca tagtgcaata gagactcata
     7141 gtgtaattgc acactatgat tataatgata aattaactgt acatacacct tgccaaaata
     7201 catttggatt tagaataata ctatctcaaa tttttgggat gtcattaaat aaagtaagag
     7261 ttataagacc tgctattgga ggctcatttg gtggaaaatt agaacttaca attgaaccag
     7321 tagcagccgc attatcaaaa atgacaagaa gaccagttaa aatggttctt acaagaaagg
     7381 aatctatgat atcaacaaga actcgtcatg ggtcttttgt aaaattaaaa actggtgtaa
     7441 ataaagatgg tgaagtaata gcacaagaca taaaaatata tacaaataca ggagcatatg
     7501 catcaagtgc tttaaatgtt ataggagcac ttagtcataa agtatttaaa gtttataaaa
     7561 taccaaatat aaagtttact gggatgcctg tatatacaaa tacaccaata gcaggagcta
     7621 tgagaggcta tgggtcacct caaatattta tggctcaaca agctcaattt gcgaaaatag
     7681 caaaggaaat aggtatggat ttagtcgatt ttcaaaataa aaatgcagta gagccagatg
     7741 atgtcgatat aatcttccac ggttctcttg gaaatcctag agtattggat tgtatagagc
     7801 aaggtaagaa gatgtttaag tgggatgaaa agaaaaaact tccaaaagaa gaaggaaaat
     7861 atttaagagg tataggtatg gcaataggtg cacatggtaa tggagttttt ggtgcacata
     7921 gagatgttgt tacattgact cttaaattaa atgaagatgg tacgttgaca ctactaacag
     7981 gagctcatga tatgggtaat ggtgttgtaa ctatgcaaac aatgatggta gctgaagttt
     8041 taggaataac acctgataaa gttgatacat ttgaaactga tacggatgca tgtacattca
     8101 accttggtga ctatgcaagt agaggggtat ttgtagaagg tggaggagct aaaaagacag
     8161 cagagaaatt gaaaaatctt atattagaag aagcagaaaa attacttgaa acatcaaaag
     8221 aagatttata cctagacaat ggatgtgtaa ttagtaaact tgatgaaaat gtaaaagcat
     8281 cactttctga tgtcgcagta tatagtcaaa gtaaatcatt aagagagtta actgttgttg
     8341 aagattattc ttcaccagct ggacgtactt cttatggtgt acattttgct gaagttttag
     8401 tagataaaga aactaaggat ataaaagtag ttgattttgt agctgtacat gatgttggta
     8461 gagttataaa tcctctaaat ttagaaggac aattagaagg tgggattcat atgggtctag
     8521 gatacgcatt gagtgaagaa ttggcatttg atgaacaagg tagacctaaa gctactgatt
     8581 ttaaaacata taaattattt agaactgtag atatgccaaa atgtcaagtt gcatttgtag
     8641 atggttatga aaaagctggg ccttttggtg gtaagagtat tggagaatgt gccgttgtac
     8701 cagttgcgcc agctgttgca aatgcagtat ataatgcaac tgatgtagag atacattcat
     8761 taccaataaa attaaaatag tagaaattaa agcagaaata acaatttatt gtatttgtaa
     8821 atagataata aaaatagatt tatttggtga ggagatatta ttatggcaaa gatattaggt
     8881 atttgtggaa gtccacgtaa aggagcaaca gaatatgcag tgttagaagc tttgaaagaa
     8941 gcagaaacta tacctggtat agaaactgag tattggtcag ttagagggaa aaaaataagt
     9001 ccttgtgtac attgtgatgc atgtataaga aaagaaacta tgtgtattat aaaagatgat
     9061 atccaagaat tagagcaaaa aatattggag gcagatggaa ttatagtagg ttctccagtt
     9121 tatgatatga atataactgc tcaacttaca gcagtattta atagacttcg tccaatgtat
     9181 ttagttcatc caggaaaact tcaaaataag gttggtgcag ctataactac tggtggaact
     9241 agatatggtg gccaagaatt gacaaaactt cctataataa atttcttcct aatgcatgaa
     9301 atgttagtgt ctggaggttt aggtggatgc tatataggtg gtacaatatg gagtaaagat
     9361 ggaaaagcaa aaggtgccca agaggatgag acaggtatgg acacagtaaa aagacttgga
     9421 aaaggtgcag cagaggcagt tatggtttct aagtttggtc ttgaaaaatg gaatgtcgta
     9481 aaagaagaat tagatgttaa aaaagatgaa aaatcacctc ttagagacca ctaaagattt
     9541 attatattat tgaatatata caaatagtga tgtaatagat tattgcatca ctattttatg
     9601 ttttaattta gattttataa attttatatt aaaaaatata gaaacaaagt gttttgagat
     9661 ttatttttaa attttaaaaa tgagaattaa aaagtgagaa gatagaaaag gttttttagt
     9721 tattaaattc tacatacatt gtatgaacta aagatagaaa agaaaaaata ataaaagcat
     9781 tgcaatttct atactaaaga gtcatggaaa aatatctagt atatatttag tattggcatg
     9841 ttaattgctt atatattaaa gtataaaaat ttaacaataa tttggaggta ttttagatgt
     9901 taaaagaaat taaatggaaa gtaaataatt tgccaaaggg cgataaggaa aattgtatca
     9961 aatttttaaa tgaagaagaa ataactaagg ttagaaattt tcacaaaagc tttcctcaat
    10021 ataaagaaac tccattagca aacctagaag gtttagcaaa aaaattaggt gttgcaggag
    10081 tatatgtaaa agatgaatct tatagatttg gattaaatgc atttaaagta ttaggtggtt
    10141 cttattctat gggtagatac ttagctcaaa gattagatac agatatatct gagttagggt
    10201 atgacaaatt gacttcgaaa gaaataaaag aaaaattagg agaaataact ttctttacag
    10261 ctacagatgg aaatcacggt agaggagttg cttggacagc taataaatta ggtcaaaaat
    10321 ctgttgtatt aatgccaaaa ggttcttctg aatttagatt aaataaaatt aaaggagaag
    10381 gtgcagatgc tagtataaca gacttaaatt atgatgatgc agtaagatta gctaatgatt
    10441 atgcagaagc tgatgaccat ggagtaatgg ttcaagatac agcatgggac ggatatgaag
    10501 aaataccagc atggataatg caaggatatg gaactatggc tcaagaagct atagagcaat
    10561 taaaagaata tggagtagat agaccaacac acgtatttgt tcaagcagga gttggttcac
    10621 ttgctggtgc agttcaaggg tatgttgctt caatatatga tgaatgccca ataacagtag
    10681 tagtagaggc tgatgaagct gattgttact ataaatcagc agaagctgga gatggaaaac
    10741 caagatttgt tggaggagat atgccaacta taatggcagg gcttgcttgt ggagaaccaa
    10801 atactatagg atttgaagta ttaaaaaatc atgcagcagc atttgtttca gcaccagact
    10861 gggtttctgc taaaggtatg agaacattag gtaatccttt aaatggtgat gaaaaggtaa
    10921 tttctggaga atctggagca gttacaactg gtcttttagt agcagctatg gaaagagaag
    10981 atttagcaga tttaagaaaa gatttaaaat tagatgaaaa ttcaagaata cttttaataa
    11041 gcacagaagg agatactgac cctgacaaat atagaagtat agtttgggat ggagaatatc
    11101 caagtatata aggaattact aaaatgcaat tattagatat tggtttacat atttagaaga
    11161 tatataagtt ctaaaattta gaaaatatat aagtatataa aatacataca ttataaaaaa
    11221 tctaggggga taatgaaatg ttaaacgaac aaagaaaaca agaagtaact gaaatatgcc
    11281 aaaaattaat tcaaaatcct agttcttctg gaaatgaaga aggtgttgta aaagcaatag
    11341 aagagtcttt tgaaaaatta ggttttgata gttggtcaag agatagatat ggaaatatag
    11401 taggatgtat aaaaggtaac aagccaggta agaaaatatt atttgatgga catatagata
    11461 cagttccagt tccagatgca agtaaatgga gtgttcctcc ttttgaagga aaaatagttg
    11521 atggaaagat atatggtaga ggaacttctg acatgaaagg tcaatatact gcaatgatgt
    11581 ctgctgtagc gtattttgct aaagacacta atagagattt tgctggagaa ctatatgtag
    11641 caggtgttgt tcatgaagaa atatttgaag gtgtttcggc tagagagata agtaaggctg
    11701 ttcaacctga ctatgttgta ataggtgagt cttcagagtt aaacttaaag attggtcaga
    11761 gaggtagagg agaaatagta gtagaaactt ttggtaaacc agctcactct gctaatccag
    11821 aaaaaggt
//
LOCUS       DAMKNB010000101        11382 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.107, whole genome shotgun sequence.
ACCESSION   DAMKNB010000101 DAMKNB010000000
VERSION     DAMKNB010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 11382)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11382)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11382
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.107"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            121..729
                     /locus_tag="PC494_003143"
     CDS             121..729
                     /locus_tag="PC494_003143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dienelactone hydrolase family protein"
                     /protein_id="HDF3913622.1"
                     /translation="MVDNLIKYIHKSDVAIVVLHEIYGINSFIEDVCQKYYKYGYDVF
                     CPELLGEKRVFPYSKVQEAYDFFINNVGFDIYKKVEKLINDLKSEYKYVFVAGYSVGA
                     TIAWRCSEDSFCDGIICCYGSRIRDYMDVIPKCPTLLVFAKHDSFDVDSISCQLSRKQ
                     NIQIEILDANHGFIDRYSNNYSDIQTKVFTIKEKSFLSKYLA"
     gene            1056..3953
                     /locus_tag="PC494_003144"
     CDS             1056..3953
                     /locus_tag="PC494_003144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HDF3913623.1"
                     /translation="MKAFKKHFLILSLIFLLIISCFNNILCFADESENSKKIRVGYCD
                     DYGIISSSKEHSYTGYGYDYLREISKYTRWEYEFVKGSWEECLDRLEKGEIDLLGPLQ
                     KNDERNKLFNFPKLSSGYEYSALYTKDSNNNMFYEDISSFKGMRVAVLRGNFHNTAFE
                     KYREENNFSVEYIYCNSIDELIESVNEKKADAFVCGSIINAKGMKIVSKFSVEPFYFA
                     TAKDKPNLVKELDYALKELKINDMYYELELYKKYFKREVNNSIAFTRQEMNFIKANPK
                     LTMVYDSEWSPVEYYDKESNSFKGISSDLMSIISKKCGIKFEYIKTKNYNESLDYIKS
                     GKATMLCGSINENDKAKRFNMKLTNPYINIPMIMVGKLDTNLNNDLNIALTSSYKSID
                     SYIEKSFENAKTTSYKSVESCLNAINEGKANLMILSSYQFDELLREGKSENLSVISVL
                     DTSYGMRIGVSNKTDPILVSILNKSIDKITEEELSDCIYSNTIDKPYKVPFGVIFKEY
                     SIQIISFVCILFLIAIKYIIYNKKKKEDYLRKIAYTDPLTGADSIDKFKINSNKLFAK
                     NNPEEYALFYIDVDKFKYINDMFGYDMGNDTLIHISNTIASELKEDEIFARVSADHFV
                     LLIKYKTDDDIKTRLNNIYNKVQILSNPKINYYKLILDCGIYKISKSDNDINTIMDRA
                     NTARKTIKGGHKNSFAFYDKEMHKKILKEKEIENSMVDALNNGEFIVYFQPKYSLSDY
                     QIIGAEALVRWDNPQKGLIPPIEFIPVFERNGFIVNIDFYVFEEVCKKIREWMDEGQK
                     VVPISVNLSRMHFVNSNFIEKFKLIVDKYKIPTRLIELELTETAVLDNIEGLLDTMNN
                     LKEKGFVISMDDFGTGYSSLNLLKELPVDILKLDRAFFTEKDESNNEKIVISNVIKMA
                     KELKMKVISEGVETISQVEFLKQIGCDMVQGYLFSKPMPVKEFEKIAFKKE"
     gene            4274..4486
                     /locus_tag="PC494_003145"
     CDS             4274..4486
                     /locus_tag="PC494_003145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HDF3913624.1"
                     /translation="MMPLILSNTGEEVVIKKISGSDKTRTFLNSIGFVVGTNVKIVSK
                     IDGNLIIDVKDTRVALDKKMASRIII"
     gene            4499..4720
                     /locus_tag="PC494_003146"
     CDS             4499..4720
                     /locus_tag="PC494_003146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HDF3913625.1"
                     /translation="MNRLKDIKCGETVKVKKLEGEGATRRRIMDMGITRGVNIFIRKV
                     APLGDPIEVTVRDYELSIRKSDAEKIIVE"
     gene            4820..6976
                     /gene="feoB"
                     /locus_tag="PC494_003147"
     CDS             4820..6976
                     /gene="feoB"
                     /locus_tag="PC494_003147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein B"
                     /protein_id="HDF3913626.1"
                     /translation="MSIKIGLIGNPNCGKTTMFNGLTGSSQYVGNWPGVTVEKKGGKL
                     KGNKDVEIVDLPGIYSLSPYTLEEVVTRNFMLDDKPDAVINIVDASNIERNLYLTTQV
                     LELGIPTVIALNMMDIVNKNGDKINIKELSEVIGCPVVEVTAVKGQGIMEAAEKAVEL
                     ASSNNKLNFKLPFVDESKDAIEKIEKIIEEKTPYIDVETRWLAIKLFERDENVIQKLD
                     ISKTILNSIEEITRNCEDELDDDSESIITANRYEFISSIISSIIKKNRKGKETVSDKI
                     DKIVTNRILALPIFALIMWGVYYIAVSSLGTIATDWTNDVLFGEIIQGNVSNFLASLN
                     VAEWLQGLVVDGLIGGVGAVLGFVPQIMLLFLLLSILEDCGYMSRVAFIMDRIFRKFG
                     LSGKSFIPMLISSGCGVPGVMSTRTIENDRDRKMTIMLTTFIPCGAKIPIIALFAGAL
                     FGGASWVAPSMYFLGIAMIIICGIILKKTSLFAGEPSPFVMELPQYHIPSAKGVLIHM
                     WDRGKAFIIKAGTIIFVACGVIWFLQSFNWSLQMVDAGDSILASLGNIVAPIFAPLGF
                     GNWQSSVATVTGLVAKENVVGTFGVLFGISDATEQDPTLLASVASMFTVASAFAFMAF
                     NMLCAPCFAAIGAIKREMGSWKWTWITLGFQTLTAYIIALLINQVGSLVLGTGGSIAG
                     AIISIFIAVAVVFVVLTYSNKNMKKEKMGKLSYMKN"
     gene            7002..7154
                     /locus_tag="PC494_003148"
     CDS             7002..7154
                     /locus_tag="PC494_003148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FeoB-associated Cys-rich membrane protein"
                     /protein_id="HDF3913627.1"
                     /translation="MATFIIAAIVVVLMALAVMYMVKNSKKNGSSCGCGCSGCSSSKS
                     CHSAKR"
     gene            7334..8044
                     /locus_tag="PC494_003149"
     CDS             7334..8044
                     /locus_tag="PC494_003149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AIM24 family protein"
                     /protein_id="HDF3913628.1"
                     /translation="MFKFDVTNELMCIARGSGKFFAKKGAMVAFKGNFNFEKLLLGPS
                     NGGGLGRALLGHVQRSLTGEQMPIMVVEGEGEIYLAQNAYHVDVISIDPGDSIYVESE
                     NLLAFSEQLNYSVKLIGSGVISQKGLFTTHLVNKTGQNQDVAIITDGNPLILEGPCCV
                     DPDALVAWTGREPYPKVSKLSWKTFIGQTSGESYHMEFVEPGQIVIIQPSERLSGLKT
                     DSTPSDRMSSGGLRLGID"
     gene            8129..8899
                     /locus_tag="PC494_003150"
     CDS             8129..8899
                     /locus_tag="PC494_003150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF3913629.1"
                     /translation="MFEKIHKRLKGYYIFLIILILWKIVCVLGIWSSYILPPPEIVLD
                     TFIKMIYDGSIFLNVYASVRRILIGFLISSLMAIPLGVLFGANKKMYEYFKPLFEFMR
                     STPPLALVPMLILWFGIGEESKIIIIILASFFPIFLNTLKGIKNCDNKLIEVGKSFNL
                     SKKRIFYKIIIPNSMLDIVVGLSLGLGYSFRAIIGAELIAASSGLGYLISDGKDMSRT
                     DVVLVGIFVIGFLGILSDYLFSKIITKFSKGKQVDLNG"
     gene            8892..9623
                     /locus_tag="PC494_003151"
     CDS             8892..9623
                     /locus_tag="PC494_003151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF3913630.1"
                     /translation="MVRSGFLLENIYKKYLVDNKEHLVLDNISLNISSEEITVILGES
                     GCGKTTLLRILAGLENATSGNVYFFNNDKKCTPKVGMVFQESRLMPWLNVSENILLHT
                     EKDNRNKVDLDKYLKMMKLEKFKNSYPNELSGGMAHRVSIARALSFNPDILLMDEPFA
                     ALDYFTRRKMQKEVVNIHKNTKKGVVFVTHNIEEAMEIAKKIIVFSKNKRIKQFSVED
                     EYNRDLTKNYYINLKKEILRELGEF"
     gene            9657..10616
                     /locus_tag="PC494_003152"
     CDS             9657..10616
                     /locus_tag="PC494_003152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NrtA/SsuA/CpmA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HDF3913631.1"
                     /translation="MTSLIMVLVGTVGCSTTNDKKDEPAKKEASLPKEINLTYVKSPL
                     NVPSILEKKDDLFGKEFKKDNIKVNFHELTTGPEQTQALAAGELDFLHALGGTSAIIA
                     ASNGVGLKITNIYSRSPKGYMLITNNDNIKSIKDLKGKKIVGPKGTILHQLLIAALAK
                     EGYTIDDVEYVNMDIPSAASALESKSADVAMLAGPVALKTINSGAKMIVNGEGLVSGI
                     IVTAVSDDFAEKYPELVKRFMKVHEETLKYMNENKDEVMDVVSKEVGLSLDETKEMYS
                     WYDFSSKITDKDIKELEDTQEFLMSNGMQQKKINIKDMLYNQN"
     gene            complement(10714..11310)
                     /locus_tag="PC494_003153"
     CDS             complement(10714..11310)
                     /locus_tag="PC494_003153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3793 family protein"
                     /protein_id="HDF3913632.1"
                     /translation="MSCCNSQFCCKNKIESSYIKWLLEVLGPVFLGSKPAEIINISFT
                     DVNREEKINDIYKYLYKCKKIDFIVIDKEKKGLKILFVNKKALSEKLKCKKTVNFLKF
                     LGYKQNTNVNAYLEHLVDKLKSDVFPDEIGIFLGYPLKDVIGFMGYSNYEVSMIKYWK
                     VYGDTKQSEDTYSKFLLHRKKMRKLLDYISVDKIVSCF"
BASE COUNT         4376 a         1176 c         2037 g         3793 t
ORIGIN      
        1 aatgcacaac ttttaaaaat aaatgattaa tccaaaaata aatttgattt tagaaaagta
       61 aattgacatg taaagaagaa tatattaaac taagtataaa aaatttgctg ttttgtaaag
      121 gtggtggata atctgataaa gtatatacat aaaagtgatg tagctattgt tgttttgcat
      181 gaaatctatg ggattaatag ctttatagaa gatgtttgtc aaaagtatta taaatatgga
      241 tatgatgtat tttgtcctga acttctggga gaaaaaagag tttttccata ttcaaaagtc
      301 caagaggcat atgatttttt tataaataat gttggttttg atatttataa aaaagttgaa
      361 aagcttataa atgatttaaa atcagagtat aaatatgtat ttgttgctgg gtatagcgtg
      421 ggagcaacta ttgcatggag atgcagtgaa gattcttttt gtgatggcat aatttgttgt
      481 tatggctctc ggattcgaga ttacatggat gtaattccaa aatgtcctac cttattagta
      541 tttgcaaagc acgattcatt tgatgttgat tctatttctt gccaactttc taggaaacaa
      601 aatatccaaa ttgagatttt agatgcaaat catggtttta tagatagata ttcaaataat
      661 tattctgata ttcaaacaaa agtatttact attaaagaaa aaagttttct gtctaaatat
      721 ttagcatgat ttagactatt ataaaatata tagaaagatt taattaatct gaaaagtttt
      781 tatgacacta ttgatattta aaatattagt agtgttatta tattttttga aataaaatta
      841 atcactagaa ttatagtgtt agttgtgctt ttatgactta taagaaacta atattagata
      901 gtgtatttaa atagataata ataaattcat tatagttgaa taagaatatt atatgagaat
      961 attgcaattt gatatattta ccattacaat aaaagtagtt acaactagaa aaccaaataa
     1021 gttaaagtaa gttggcaaat tggaggtttt taaatatgaa agcatttaaa aagcacttct
     1081 tgatactttc tttgatattt ttacttatta tatcatgttt taacaatata ctatgctttg
     1141 ctgatgagtc tgaaaattca aaaaaaataa gagttggata ttgtgatgac tacggaataa
     1201 tatcctcatc aaaagagcat tcttatacag gatatggtta tgattatcta agagaaatct
     1261 caaaatatac aagatgggaa tatgaatttg taaaagggtc ttgggaagaa tgtttagaca
     1321 gactagaaaa gggtgaaata gacttactcg gacctttaca gaagaatgat gaaagaaata
     1381 aactatttaa ttttcctaaa ctaagttcag gatatgaata tagtgcacta tatacaaagg
     1441 atagtaacaa taatatgttt tatgaagata taagttcctt taagggaatg agagtagctg
     1501 tacttagagg aaactttcat aatactgcat ttgagaagta tagagaagaa aataattttt
     1561 cagttgaata tatatactgt aattctattg atgaattaat tgagtccgtc aatgaaaaaa
     1621 aggcagatgc atttgtttgt ggaagtatta taaatgctaa aggaatgaaa atagttagca
     1681 aattttcagt agaacctttt tattttgcta ctgcaaaaga taaacctaat ttagtaaaag
     1741 aattagatta tgctttaaaa gaattaaaaa taaatgatat gtattatgag ttggaattat
     1801 ataaaaaata tttcaaaaga gaggtcaata attccatagc atttactcgg caagaaatga
     1861 attttattaa agcaaaccca aaacttacta tggtatatga ttcagagtgg tctcctgtag
     1921 agtattatga taaagaaagc aattcattta aaggtataag ttccgattta atgtcaatta
     1981 tatcaaaaaa atgtggtata aaatttgaat atattaaaac aaaaaattat aatgagagtc
     2041 ttgattacat aaaaagtggt aaggcaacta tgctatgtgg ctcaatcaat gaaaatgata
     2101 aggcaaaacg atttaatatg aaattgacaa atccatacat aaatattcca atgattatgg
     2161 taggaaaatt ggataccaat ctcaataatg atttaaatat tgctttaact agtagttata
     2221 agtctattga ttcttatata gaaaagagtt ttgaaaatgc taagacaaca tcttataaga
     2281 gtgtagaaag ttgtctaaac gctataaatg aaggtaaagc aaacttaatg atacttagct
     2341 cttatcagtt tgatgaactt ttaagagaag gaaagagtga gaatttatct gttatatctg
     2401 ttttagatac aagctatggg atgcgtatag gggtatcaaa taaaactgac cctatattag
     2461 tgtctatttt aaataaatca atagacaaaa ttactgaaga agaattaagt gattgtatat
     2521 attctaatac tattgacaaa ccttataaag taccatttgg tgtgattttt aaagaatatt
     2581 caatacaaat tatttctttt gtatgtattt tattcttaat tgctattaaa tatataattt
     2641 ataataaaaa gaagaaagag gattatctaa ggaagatagc atatacagac ccattgacag
     2701 gagcagatag tatagataaa tttaaaataa attctaataa actgtttgct aaaaataatc
     2761 cagaagaata tgcgttgttt tatatagatg ttgacaaatt taaatatata aatgatatgt
     2821 ttggatatga tatgggaaat gatactttga tacatatatc aaatactatt gcaagtgaat
     2881 taaaggaaga tgaaattttt gcaagagttt ctgctgacca ttttgttctt cttattaagt
     2941 ataagacaga tgatgatatt aaaacaaggt taaacaatat ttacaataag gttcaaatac
     3001 ttagtaatcc taaaataaac tattataaat tgattttaga ttgtggtata tataaaataa
     3061 gtaaaagtga taatgacata aatactatta tggatagagc taatactgca agaaaaacta
     3121 taaaaggtgg tcataaaaat tcatttgctt tttacgataa ggaaatgcac aaaaaaatat
     3181 taaaagagaa agaaattgaa aattcaatgg tagatgctct taataatgga gaatttattg
     3241 tttattttca acctaaatat agtctttcag attatcaaat tataggggca gaggctcttg
     3301 ttcgttggga taatccacaa aaaggtctaa taccaccaat agaatttatt cctgtatttg
     3361 agaggaatgg ttttattgta aatattgatt tctatgtatt tgaggaagtg tgtaaaaaga
     3421 ttagagaatg gatggatgaa ggacaaaaag tagtacctat atctgtaaac ttgtctcgaa
     3481 tgcattttgt aaatagtaat tttatagaga agtttaaatt aattgtagat aaatacaaaa
     3541 ttccgacaag acttatagaa ttagagctaa cagaaacagc agtattagat aatatagaag
     3601 gattacttga tacaatgaac aatttgaaag aaaaggggtt tgtaatctct atggacgatt
     3661 ttggtacagg atattcctct cttaatcttt taaaagaatt gcctgttgat atattaaaac
     3721 tagatagagc attttttaca gaaaaagatg agagtaataa tgaaaaaatt gttatatcta
     3781 atgtcattaa aatggcaaag gaactgaaaa tgaaagtaat atcagaaggt gtagagacta
     3841 tttcgcaagt agaatttcta aagcagattg ggtgtgatat ggtacaagga tatttgtttt
     3901 ctaagccaat gcctgtaaaa gagtttgaaa aaatcgcttt taaaaaagaa taaagcaatg
     3961 tgtaaataat gacatatata ataaaggtgc tttaatatta gttgagtata ctattttaga
     4021 gcatctttat ttttgtatta atttttacga ttttattaat aaaataaatc aaatgagaaa
     4081 aaaaatcaaa agaatacaat aatcacttgc aaaaaatata ctattgtgat agacttaaat
     4141 caaaattagg aattgtaaaa agaaggaaaa aataggatat tattttaata gattaagatt
     4201 taaggtattg taatttatat ataagataac gattgcttgt aaatttaaat tactttaaga
     4261 ggagggatat tatatgatgc cattgatatt atcaaataca ggtgaagaag tagttataaa
     4321 gaaaatttcg ggaagtgata agacgaggac ttttttaaat agtataggtt ttgtagtggg
     4381 tacaaatgtt aaaatagttt ctaagataga tggtaactta ataatagacg taaaagatac
     4441 tagagttgca ttagataaaa aaatggcaag tagaataata atatagggag gtaatgacat
     4501 gaacagactg aaggatatta agtgtggaga gactgtaaaa gtcaaaaagt tagaaggaga
     4561 aggagctaca cgaagacgta taatggatat ggggattaca agaggtgtta atatatttat
     4621 aagaaaagta gctcctcttg gtgacccaat tgaggtaaca gtcagagatt atgaactatc
     4681 aattcgtaag tcagatgcag aaaaaattat tgtggaataa taaagattaa ttagagtagg
     4741 gttaatgtaa tcatataatg agaatgattt tctgtatcac aaacagtgat gtatttaaat
     4801 aataatggag ggaatggaaa tgtcaataaa aataggtctc ataggaaatc ctaactgtgg
     4861 taagacaaca atgttcaatg ggcttacagg ctcatcacaa tatgttggta actggccagg
     4921 agtaacagtt gaaaaaaaag gtggaaaatt aaaaggaaat aaagatgtgg aaatagtaga
     4981 tttaccaggt atttattctt tatctccata tacattagaa gaagtagtta cacgtaattt
     5041 tatgctagat gataagccgg atgcagtaat aaatattgta gatgcatcaa atatagagag
     5101 aaatttatat cttacaactc aagttttaga gctaggtata ccgaccgtta tagctcttaa
     5161 tatgatggat attgtaaata agaatggtga taagataaat attaaagaac tatctgaagt
     5221 tataggttgc ccagtggtag aagtaacagc agttaaaggt caaggaatta tggaagctgc
     5281 tgaaaaggca gttgaacttg caagtagtaa caataaatta aatttcaaat taccctttgt
     5341 tgatgaaagt aaggatgcaa tagaaaaaat tgaaaaaata atagaagaaa agactccata
     5401 tatagatgta gaaacacgct ggttagctat aaagctattt gagagagatg aaaatgttat
     5461 acaaaaactt gatatttcta aaacaatatt gaatagtatt gaagaaataa ctagaaattg
     5521 tgaagatgaa ttggatgatg atagtgaaag tataataaca gccaatcgtt atgaatttat
     5581 tagttcaata atttcaagta taataaagaa gaatcgaaaa ggtaaggaaa ctgtatcaga
     5641 taagatagat aagattgtaa caaatcgtat actagcatta cctatttttg cacttataat
     5701 gtggggagtt tactatatag cagtaagttc attgggtact atagcaactg attggacaaa
     5761 tgatgtactg tttggagaaa ttattcaagg caatgtaagt aattttctag cttctttaaa
     5821 tgtagcagag tggttacaag gacttgtagt tgatggtcta attggtggag ttggagcagt
     5881 actaggattt gtaccacaaa tcatgctttt attcttatta ttatcaatat tagaagattg
     5941 tgggtacatg tcacgtgtag cttttataat ggatagaatt ttccgtaagt ttggtctttc
     6001 aggaaaatca tttataccaa tgcttataag ttcaggttgt ggagttccag gagttatgtc
     6061 aactcgtact atagagaatg atagagatag aaaaatgact attatgttaa ctacattcat
     6121 tccatgtgga gctaagattc caataatagc attatttgca ggggcattat ttggaggtgc
     6181 ttcatgggta gctccatcaa tgtatttctt aggtattgca atgataatca tttgtggaat
     6241 tatattaaag aaaactagtt tatttgcagg agaaccatct ccatttgtta tggaattacc
     6301 tcaatatcat attccaagtg caaaaggtgt tttaatacat atgtgggata gaggaaaagc
     6361 atttataatc aaagcaggaa caattatatt tgttgcttgt ggagtaatct ggttcttaca
     6421 atcatttaat tggtcattac aaatggtaga tgctggagat agtatattag ctagcttagg
     6481 aaatatagtt gcaccaatat ttgctcctct tggatttgga aattggcaat catcagtagc
     6541 aacagttaca ggtctagtag ctaaggaaaa tgtagttgga acatttggag ttttatttgg
     6601 tatatcagat gcaacagagc aagacccaac acttcttgct tcagttgcaa gtatgtttac
     6661 agtagctagt gcgtttgcat ttatggcatt taatatgctt tgtgcacctt gttttgcagc
     6721 tattggagcc ataaaaagag aaatgggttc atggaaatgg acatggatta cattaggatt
     6781 ccaaacttta acagcgtata taattgctct tcttataaat caagttggaa gtttagtttt
     6841 aggtactgga ggaagtattg ctggggcaat aatatctata tttatagcag tagcagtagt
     6901 ctttgtagtt ttaacttatt caaataaaaa tatgaaaaaa gaaaaaatgg gtaaattaag
     6961 ttatatgaaa aattaattca tataaataag gagtgatgaa tatggctaca tttattatag
     7021 cagctattgt agtagtatta atggcactag ctgtaatgta tatggttaaa aattcaaaaa
     7081 agaatggtag cagttgtgga tgtggttgtt ctggatgctc aagtagtaag agttgtcata
     7141 gcgctaagag ataaatagga taagagcctg ataaaaagtt aaattgcttt attatcaggt
     7201 tcttattttt tgtataaata acaaatttca tatttgaagt aggttagact atgctgtaat
     7261 tttactgtat aattatatat aaatatatga ttaggaggga ttattgctaa attaagcaat
     7321 ataagtgaat attatgttta aatttgatgt tacaaacgag cttatgtgta tagcaagggg
     7381 aagtggtaaa ttttttgcaa aaaaaggtgc tatggtagcc tttaaaggaa attttaattt
     7441 tgaaaaattg ctgttaggtc caagtaatgg cggtggattg ggaagagcat tattaggtca
     7501 tgttcagagg tcattgacag gagaacaaat gccaataatg gtggttgaag gtgaaggtga
     7561 aatttaccta gctcaaaatg cttaccatgt agatgtaata tcaattgacc caggtgattc
     7621 catttatgtt gagagtgaaa acttattggc attttctgaa caattaaatt acagtgtaaa
     7681 attgattggt tcaggggtaa tatctcaaaa aggtcttttt actacacatt tagtaaataa
     7741 aacaggtcaa aatcaagatg ttgctataat aacagatggt aatcctctaa ttcttgaagg
     7801 accttgttgt gttgacccag atgcattagt agcttggact ggaagagaac catatcctaa
     7861 agtatcaaaa ctatcatgga agacttttat tggtcagact tcaggagaat cttatcatat
     7921 ggaatttgtt gaacctggac aaatagtcat tatacaacca tctgaaagat tgtctggctt
     7981 aaaaacagat tctacacctt ctgatagaat gagttcaggt ggattaagac ttggcataga
     8041 ttaaatctta tgatatagct taattattat ttaagatatt aaaaaataaa aagggtagca
     8101 gggatagata tgttaaaagg agttttatat gtttgagaaa attcataaaa ggcttaaagg
     8161 atattatatt tttttaataa ttttaatttt atggaagata gtatgtgttt tgggtatatg
     8221 gagtagctat attctgcctc ctcctgaaat agtcttagat acttttataa aaatgatata
     8281 tgacggttct attttcttaa atgtttatgc cagtgtaaga aggatattaa taggtttttt
     8341 aataagttca ttgatggcta taccacttgg agttttattt ggagcaaata aaaaaatgta
     8401 tgaatatttc aaaccactat ttgaatttat gcgaagtaca cctccactag ctttggtgcc
     8461 aatgcttatt ttatggtttg gtataggtga agaatctaaa attataatta ttattttggc
     8521 atcctttttt ccaatatttt taaatacatt gaaaggtata aaaaattgtg acaataaatt
     8581 aatagaagta ggtaaatctt ttaatttatc taaaaagaga attttttata aaataataat
     8641 ccctaattct atgctggata ttgttgttgg acttagttta gggcttgggt atagttttag
     8701 ggctataatt ggagcagagc ttattgcagc ttcttcagga ctaggatatt tgatttctga
     8761 tggaaaagat atgtctagaa ctgatgttgt attggtagga atttttgtta ttggattttt
     8821 aggtatactt tcagattatc tattttcaaa gataataaca aaatttagca aagggaagca
     8881 ggttgattta aatggttaga agtggatttt tgctagagaa tatatataag aaatatttag
     8941 ttgataataa agagcattta gttcttgata atatatcttt aaatatatct agtgaagaga
     9001 taactgttat attaggtgaa agtggatgtg ggaaaacaac gctacttaga attttagcag
     9061 ggcttgaaaa tgctactagt ggaaacgtat atttttttaa taatgataaa aagtgtactc
     9121 caaaagtagg aatggtattt caagaaagta gacttatgcc atggctgaat gtaagtgaaa
     9181 atatactttt acatactgaa aaagataata gaaataaagt tgatttagac aagtatttaa
     9241 aaatgatgaa gcttgaaaag tttaaaaact catatccaaa tgaattatca ggaggaatgg
     9301 ctcacagagt aagtatagca agagcacttt ccttcaatcc cgatattttg ctgatggacg
     9361 aaccatttgc agcactagat tacttcacaa gaagaaaaat gcaaaaagaa gttgtaaata
     9421 tccataaaaa tactaaaaaa ggtgtagtat ttgtaactca caatattgaa gaagctatgg
     9481 aaatagcaaa gaaaataatt gtttttagta aaaataaaag gattaaacaa tttagtgtcg
     9541 aagatgaata taatagagat ttaactaaaa actattatat aaacttgaaa aaagaaatat
     9601 taagggaatt gggggagttt taattgatta aaagaaacaa aaagatttta gcagtaatga
     9661 catctttaat aatggtgttg gttgggactg taggatgttc aacaacaaat gataagaaag
     9721 atgaacctgc aaaaaaagag gctagtttac ctaaggaaat aaatttaact tatgtaaaat
     9781 caccacttaa tgttcctagt atattagaaa aaaaggatga tttatttgga aaggaattta
     9841 aaaaggacaa tataaaagtc aatttccatg aattgacaac aggaccagag caaactcaag
     9901 cattagcagc aggtgagcta gactttttac atgcattagg aggaacgtct gcaataatag
     9961 ctgcatcaaa tggtgttggt cttaaaatta cgaatattta tagccgttca ccaaaaggat
    10021 atatgcttat aactaataat gataatatta aatctataaa agacttaaaa ggtaaaaaaa
    10081 ttgtaggtcc aaaagggact atacttcatc aactgttgat tgctgcactt gctaaagaag
    10141 gctatactat agatgatgtt gaatatgtaa atatggatat tcctagtgct gcttctgcat
    10201 tagaaagtaa aagtgctgat gtagcaatgc ttgcaggtcc agtggcattg aaaacgataa
    10261 attcaggtgc caaaatgatt gtaaatggag aaggattagt aagtggaata atagttactg
    10321 ctgtaagtga tgactttgct gaaaaatatc ctgaattagt aaaaagattt atgaaggttc
    10381 atgaagaaac tttaaaatat atgaatgaaa acaaggatga agtgatggat gttgtatcta
    10441 aagaagttgg tttatcttta gatgaaacaa aagaaatgta ttcttggtat gactttagtt
    10501 ctaaaataac ggacaaggat ataaaagaat tagaagatac acaggaattt ttgatgtcta
    10561 atggaatgca acaaaagaaa ataaatatta aagatatgtt gtacaatcaa aattagaata
    10621 ctttaaaata ttaaagtgga aaatacaccc ttatttatta tggaaactgt atggtaaaag
    10681 agggtgtatt tttattatta tacaaaaaca caattaaaaa cagcttacta ttttatctac
    10741 acttatgtag tctagtaatt ttctcatttt cttacggtga agtaaaaact tcgaatatgt
    10801 gtcctcggat tgttttgtgt caccataaac tttccaatat ttaatcatag aaacttcata
    10861 attactatat cccataaatc caatcacatc tttaagagga tatcctaaaa aaatacctat
    10921 ttcatcagga aaaacatcac tcttaagttt atctactaaa tgctctaaat aagcattaac
    10981 attcgtattt tgtttgtatc ctaaaaactt taaaaagttt actgtttttt tacattttaa
    11041 tttttctgat aatgcttttt tatttacaaa taagattttt aatccctttt tttctttatc
    11101 aataactata aaatctattt tcttacactt atatagatat ttataaatat cattaatttt
    11161 ttcctctcta tttacatcag taaacgaaat atttattatt tcagcaggtt tagagcctaa
    11221 aaagactgga cctaaaactt ctaaaagcca ttttatatat gatgattcaa ttttattttt
    11281 acaacaaaat tgtgaattac aacaagacat aaaagataac ctccttcaaa tgaaaattaa
    11341 tatcaagtaa ttagattata ctatgaatga taatcaatat ca
//
LOCUS       DAMKNB010000102        11042 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.108, whole genome shotgun sequence.
ACCESSION   DAMKNB010000102 DAMKNB010000000
VERSION     DAMKNB010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 11042)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11042)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11042
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.108"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            complement(81..713)
                     /locus_tag="PC494_003154"
     CDS             complement(81..713)
                     /locus_tag="PC494_003154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CatB-related O-acetyltransferase"
                     /protein_id="HDF3913633.1"
                     /translation="MTIPSSNKVYPRSNDYQTVYLKNVITRENIEVGDYTIYNDFYND
                     PRDFEKNNVLYHYPINNDKLIIGKFCSIACNAKFLMTSGNHSMKSKSTYTFPIFYEEW
                     KLDINHITDAWDNKGNIIIGNDVWIGYDSIIMSGVNIGDGAIIGTRAVVTNDVPPYSI
                     VGGVPAKIIKKRFNNDTISKLLEIKWWDWPYKKIQSNIKHIQSGNIDKLV"
     gene            complement(785..1138)
                     /locus_tag="PC494_003155"
     CDS             complement(785..1138)
                     /locus_tag="PC494_003155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integrase DNA-binding domain-containing protein"
                     /protein_id="HDF3913634.1"
                     /translation="MSTEKRRDNKDRILRTGESQRKDGRYAYKYVYSFGKAQFVYSWK
                     LVPTDKPPKGKRDDISLRDKEKAIQNDLDDSIDTIGKKMTVCQLYAKKNVLRKNIRLN
                     TKKGRHYLMKILNKE"
     gene            complement(1216..1419)
                     /locus_tag="PC494_003156"
                     /pseudo
     CDS             complement(1216..1419)
                     /locus_tag="PC494_003156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262306.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
     gene            1484..1621
                     /locus_tag="PC494_003157"
     CDS             1484..1621
                     /locus_tag="PC494_003157"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3913635.1"
                     /translation="MVFQPIPFLWAEPCHTGVSLYCGTGYGKTTVPKVIHKSLYSSSL
                     D"
     gene            complement(1809..2039)
                     /locus_tag="PC494_003158"
     CDS             complement(1809..2039)
                     /locus_tag="PC494_003158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF3913636.1"
                     /translation="MKPTKEVLPFTIILLAVHGDVNAINVILKHFEHYIIRLSQKTLF
                     DEYGNPYIHVEEETKRMLGTKLITAILRFNLS"
     gene            complement(2041..2448)
                     /locus_tag="PC494_003159"
     CDS             complement(2041..2448)
                     /locus_tag="PC494_003159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HDF3913637.1"
                     /translation="MVDEKTIEHQFDSFCKTVLRNYARDIYDENKRRNDYLVSLESLS
                     LAELSKLSILDDYDSNYICMVSYDYNIRIEDVLMAQAIGKLTKRKQDIILLSFFLNMT
                     NADIATLMDLAENTIHYHKTNALKELKELMQEH"
     gene            complement(2809..3247)
                     /locus_tag="PC494_003160"
                     /pseudo
     CDS             complement(2809..3247)
                     /locus_tag="PC494_003160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729090.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            complement(3261..4187)
                     /locus_tag="PC494_003161"
     CDS             complement(3261..4187)
                     /locus_tag="PC494_003161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3913638.1"
                     /translation="MSDILSRITNKIGDKNIVDKLSALSKSDLNSLLLEVFDRQANTL
                     TATDILKSYQLNRFTIPSGIDPEEIHALESKLLRKAFNMDIKTIMLSPSAPLGSCSVF
                     GSVDQYNVVSALRGTETLADPSNMLAIIIADKLKRKEENNTIPIHMATTARVIRAQNF
                     VGKGLYSHFGLYCMVSSGIDTGSYTCEKMLLEKHLNYYKDILSEIENVRFSIILRKRN
                     GYKDNDGFFDRMVETIKLIFPNIELSIHNDDVDNNYYKGINFKLSVKQGNETVEIVDG
                     GFVDWTYQMLGNKKERCLISGIGLERFLVAVS"
     gene            complement(4312..5094)
                     /locus_tag="PC494_003162"
     CDS             complement(4312..5094)
                     /locus_tag="PC494_003162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside 6-adenylyltransferase"
                     /protein_id="HDF3913639.1"
                     /translation="MTKTQQEMIQNVLEFSKRDSRIIGLAISGSYITKSLDEYSDLDF
                     LIVADDKSYEEVIEERLLIVEQFGTLVSAFTGEHVGEPRLIISLYDSPVLHVDFKFTT
                     LDGLLDRVEDSAILYEENNCITEIYSKKEAYFPTPDLQWIEDRFWIWVHYTCTKIGRR
                     ELFETIDFLSFLRQSVLASLIQLLLGKLPRGVRKIELDAPQYIEALEKTVANHEYKSC
                     VNALQATINLYLELREELSQSPIVRKVEAERVALQYFQDLIK"
     gene            complement(5250..5870)
                     /locus_tag="PC494_003163"
     CDS             complement(5250..5870)
                     /locus_tag="PC494_003163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HDF3913640.1"
                     /translation="MHLIDFMNEDIKKKLVKKTYKKKETILFAEQENEYVILMIDGIA
                     EAFILNVKGNISTIHLYRSGSFFGEMEQFNDGKKPVEIVAFTDCNVYKLHRDDFLNWL
                     RGDFEATKFLIREISSKLVVNAELIEELSSLSVKERLLRCISLHYYRSELNLLTKKQL
                     ASEVNAPIRSINRAINECVQEHLIAYENKRFSVINQREVLKNLPTT"
     gene            complement(5997..6665)
                     /locus_tag="PC494_003164"
                     /pseudo
     CDS             complement(5997..6665)
                     /locus_tag="PC494_003164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331151.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
     gene            6757..7572
                     /locus_tag="PC494_003165"
                     /pseudo
     CDS             6757..7572
                     /locus_tag="PC494_003165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897377.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
     gene            8243..9010
                     /locus_tag="PC494_003166"
     CDS             8243..9010
                     /locus_tag="PC494_003166"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HDF3913641.1"
                     /translation="MKRKVQVKNITIGEGRPKICVPIIGKNKKDIIKEAKELKDACLD
                     IIEWRVDFFENVENIKEVKEVLYELRSYIHDIPLLFTFRSVVEGGEKLISRDYYTTLN
                     KEISNTGLVDLIDVELFMGDEVIDEVVNFAHKKEVKVIISNHDFNKTPKKEEIVSRLC
                     RMQELGADLPKIAVMPQNEKDVLVLLEATNEMFKIYADRPIITMSMSGMGVISRLCGE
                     IFGSALTFGAAKSVSAPGQISFKELNSVLNLLHKSIN"
     gene            complement(9343..10020)
                     /locus_tag="PC494_003167"
     CDS             complement(9343..10020)
                     /locus_tag="PC494_003167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3913642.1"
                     /translation="MIVIEGSDKFKIAKEYIDVEYTLFSKVTFRYEKLKFKDNAELEK
                     IKMFKYKNGYIPNKLNLSFGYGFSSYKKQIIRETVDTLRLTEIFSSENIEDIKFIKDG
                     TKKLEISIEKVVKFKRRKKRNYVCCYCPDMYRDIKLDKESINKIYNRKIKIEREVNIF
                     EDEDVIINKKVLKFPKSWTKNMQKYWLSENKYPIHSTVIDDDRYKCCNVQYTKNRVII
                     LYYIYNH"
     gene            complement(10170..10487)
                     /locus_tag="PC494_003168"
     CDS             complement(10170..10487)
                     /locus_tag="PC494_003168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF3913643.1"
                     /translation="MNYIGKRLKEERKKANLTSKEFANMVGVSPWYITQIESGKKNPS
                     LKTFIKFVNILNISADVLIKDITSTGKTYLENDINEELKDLNSRELNLISQIIDIIKK
                     NKI"
     gene            complement(10509..10847)
                     /locus_tag="PC494_003169"
     CDS             complement(10509..10847)
                     /locus_tag="PC494_003169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF3913644.1"
                     /translation="MANIGKIIGDRIKVYRTKLGYSQEFLAEKAGLHPTYIGQIERAE
                     TNTSINIIMKIATALDIPLELLFANIITTEGVDNSVPLECYEMINKLTEKEQIAMLEL
                     IKCIIKYKEI"
BASE COUNT         3686 a         1726 c         1560 g         4070 t
ORIGIN      
        1 taaaataata tacaaatttt gaaaaagctc ttataaaatg attattaaag taaagtttaa
       61 tataaataaa ttataaaata ttaaactaat ttatcaatat ttcctgattg aatatgctta
      121 atgtttgatt gaattttttt atatggccaa tcccaccatt taatttctaa taattttgaa
      181 attgtatcat tattaaatct cttttttata atttttgcag gtactcctcc aacaatagaa
      241 tacggtggaa cgtcattagt aactactgct cttgttccaa taattgcacc atcaccaata
      301 tttacacctg acataattat agaatcataa cctatccaca catcatttcc aattataatg
      361 ttacccttat tgtcccaagc gtccgttata tggttgatat cgagtttcca ttcttcataa
      421 aagatgggaa aagtatatgt ggattttgat ttcattgagt gatttccact agtcattaga
      481 aattttgcat tacatgctat tgagcaaaac ttaccaatta ttaatttatc attgtttata
      541 gggtaatgat acaatacatt gtttttctca aaatctcttg ggtcattata aaagtcatta
      601 tatattgtgt aatctccaac ttctatattt tcccttgtta ttacattttt aagatataca
      661 gtttgataat cattacttct tggatatacc ttatttgaac ttggaatagt catatttaaa
      721 tctctccttt aatatatatt atgtttttga ctattccact actacaatac atctcttcac
      781 agaatcactc cttgttaaga atcttcataa gataatggcg tcctttttta gtgttaagtc
      841 ggatattctt tcttagtaca ttctttttag cgtataactg acaaactgtc attttcttac
      901 caatagtgtc aatgctatca tcaaggtcat tttgtattgc tttttcctta tcccttaatg
      961 atatatcatc acgttttccc tttgggggtt tatcagtagg tacaagtttc caagagtaaa
     1021 caaattgtgc tttaccaaat gaatatacat acttatatgc gtatcttcca tcttttctct
     1081 ggctctctcc agttcttaaa attctatctt tattatctcg tcttttttca gttgacatga
     1141 taagaagctc ctctcaataa ccgaattgag cttgatacgt catatgaata ttataacata
     1201 taaggctcaa tttcattaga taacgtcaag tgtatcaacg attttctcaa attgttttct
     1261 ctttatttga atgcgattgc tattcataat gacccagcca gaatcaaggt tttcatcagc
     1321 aagtttacgt aattttttct ctccaatacg aaagtatttt gacgcttatt caatcgtcaa
     1381 ggtatatttt tcccaaatag gtacatcagt attgttcata gaatgtatca ctcctttcta
     1441 tgttcgtagt tcagaagtag atagatggct ttggtaagct ccattggtat ttcaaccaat
     1501 cccattctta tgggcagaac cgtgtcatac aggtgtatca ttatactgtg gtacaggtta
     1561 cggcaaaaca accgttccaa aggttattca caaatcacta tatagtagct ctcttgatta
     1621 aggtcatggc gtatagtatt tgttggctat ctgtatcaca aacgtatcta tctactttat
     1681 tcagttgtca aagaacagtc ggcattgatt tgcctataaa aaatcacaat agcttatggg
     1741 cttttataga caaataatta gtgattctcc atgtaccaaa tagcttgata catggagaga
     1801 gggcgagatt aagacaaatt aaatctcaaa atagcagtga ttagttttgt tcctagcatt
     1861 cgctttgttt cttcttctac atgaatatag ggatttccgt attcatcaaa taaagttttc
     1921 tgtgaaagac gaatgatata gtgttcaaaa tgtttaagta ttacgtttat tgcatttaca
     1981 tcgccatgta cagcaagtaa aataattgta aaaggtaata cttctttagt aggtttcatt
     2041 tcaatgttcc tgcatgagtt ctttcaactc ttttagtgca tttgttttgt gataatgtat
     2101 ggtattttct gctaaatcca tcaatgttgc tatgtcagca tttgtcatgt tgagaaagaa
     2161 tgaaagtaga attatatctt gttttctttt tgtaagtttt ccgattgctt gtgccattaa
     2221 tacatcttca attcgtatgt tgtagtcgta agaaaccata cagatgtagt tagaatcata
     2281 atcatctaaa atactcaatt tacttaattc tgcaagtgac aaagattcga gagataccaa
     2341 ataatcattt ctgcgtttat tttcgtcata aatatctcta gcatagttac gcaaaactgt
     2401 tttacagaaa ctgtcgaatt gatgttcaat tgtcttttca tcaaccataa gatttcaccc
     2461 tctttccatc gcaaggagtt aaataacctt gcttactcct atcacggtgg gagggcgtta
     2521 aatcttcgat aaatttcaaa aaaaaagaga aaaaaataca cactctgcct atagggcaaa
     2581 aatgtgtatt ctttaaaacg tatttaattt atattggttg taagccacca ccatattgat
     2641 gtatggaaat atgcattggc tagcttttca taaaaataca aagatgcata agaaattaat
     2701 agaggggaaa aacttattct gttattaaaa agtaggttaa ttctaataaa tgctattgcg
     2761 gtcgaattaa actatataca tggcaatcaa tcatgtttct attctttatt atgaattgtg
     2821 acagtattct tcaatcttaa agccacattt tacttgactc tctattgtag gaatatacat
     2881 tagcatgaat tttgttaagg ttgtattttt caaaggcaat tttgcatatt tcttttactg
     2941 catttgttgc tatccctttg ccccaatagt tcctagcaag tcagtaacct aattcagcat
     3001 ttttattaat agaggtatct tcttcaaatg ttaggctgat acttccaata gccctttctt
     3061 gataaaaaat agcatagcta agttgtttaa catctgaagt tgtcaaacaa aaactaataa
     3121 aatctctagc gttttgctac ctataagggt gggggaagtt gtcacgaaga ttgtttgcaa
     3181 tttctttatc attcgcaaac tcaactaaat cggtaatata agcataattc cactctataa
     3241 gttccatttt tcttctcctt ttatgaaaca gctacaagaa atctttctaa gccaatacca
     3301 cttatcaaac agcgttcttt tttatttcca agcatttgat aagtccagtc aacaaatcca
     3361 ccgtcaacta tttcaacggt ttcatttcct tgtttgaccg ataatttgaa attgatacct
     3421 ttataataat tattatcaac atcatcatta tgaattgata actctatatt aggaaaaata
     3481 agtttgatag tttcaaccat tctgtcgaaa aatccgtcat tatctttgta tccgtttctt
     3541 ttgcgtagaa taatagagaa acgaacattt tctatttcac ttaatatatc tttataatag
     3601 tttaagtgct tttctaacaa cattttttca caagtgtaag accctgtatc tataccagat
     3661 gaaaccatac aatataagcc aaaatgtgaa tataaacctt tacctacaaa attttgtgct
     3721 cttattaccc tagcagtagt agccatgtgg ataggtatgg tattattttc ttcttttctt
     3781 tttaatttat cagcaataat tattgccaac atatttgagg ggtctgcaag tgtttctgtc
     3841 cctcgtagag cacttactac attatattga tctacggagc caaaaacgct acagctacct
     3901 aatggagcag agggagaaag cataatcgtc ttgatatcca tattgaatgc ttttctcaat
     3961 aattttgact ccaaagcatg aatttcttct ggatctatac cgctagggat agtaaatcta
     4021 tttagttggt atgactttag aatatcagtt gcagttaaag tatttgcttg tctatcaaac
     4081 acttctaata gaagtgagtt caaatctgat tttgatagag ctgataactt atcaactata
     4141 ttcttatccc caattttatt tgtaattcta cttaaaatat cactcatagt tatcctccat
     4201 actgttactt tcaaaataat tatagaattg ttacaacaac taatctaggt catttgacca
     4261 aaaatgaaaa aacactgaat atttactatt caatattttt ttactttggg tttatttgat
     4321 taaatcttga aaatactgta atgcaaccct ttcagcttca acctttcgga caataggact
     4381 ttgtgataat tcctctctta attcaagata caggttgata gtagcctgca atgcattaac
     4441 acagctttta tattcatggt tagcaaccgt cttttctaat gcttcaatat attggggtgc
     4501 gtccaattca atttttctaa ctccacgagg taatttacct aagagaagct gtattaacga
     4561 ggcaagtact gattgtctta aaaaagataa aaaatcaatt gtttcaaata gttctctacg
     4621 tccaatctta gtgcaagtgt aatgaaccca aatccaaaat ctatcttcaa tccactgtaa
     4681 gtctggagtt gggaagtatg cttctttttt agaataaatt tctgttatgc agttgttttc
     4741 ttcatagaga atagctgaat cttcaaccct atctagtaaa ccatctaagg ttgtaaactt
     4801 aaaatcaaca tgaagaacag gggaatcata gagggaaatt atcaatcgag gttctccaac
     4861 atgttcgcca gtaaaagcag aaactaatgt tccaaactgt tccacaataa gtaatctctc
     4921 ttcgataact tcttcatagg atttatcatc tgctacaatc agaaaatcca aatcagaata
     4981 ttcatctaac gattttgtga tataagaacc gctaattgca agtcctatta tcctactatc
     5041 tctttttgaa aattctaata cgttttgtat catttcctgt tgtgttttag tcataatata
     5101 acacctctca ctgtctttta ttagctatca atccaacata attatgcata ggagtattat
     5161 ataatgaaga aataaaaaaa aataggtcac ttgacccgaa ataaaaaagt attgaataat
     5221 tattatccaa tacttttttg aaattatact tatgttgtag gaagattctt taatacctct
     5281 cgctgattaa ttacactgaa tcttttgttt tcataagcaa ttagatgttc ttgtacacat
     5341 tcatttatag cacgattaat gcttctaatc ggagcgttta cttcgctagc aagctgtttt
     5401 ttggtaagca gatttaattc acttctataa tagtgtaagg atatacacct cagaagtcgt
     5461 tctttaacac ttaaagatga taattcttca attaattcag catttacaac taatttacta
     5521 gatatttctc gaatcagaaa ttttgtagct tcaaaatctc cccttaacca gtttaaaaaa
     5581 tcatctctat gaagtttata tacattacaa tctgtgaaag cgacaatttc aacgggtttt
     5641 ttcccatcat taaattgttc catttctcca aaaaaactac cacttctata aagatgaata
     5701 gttgagatgt ttcctttcac atttaagatg aatgcttctg caataccgtc aatcataaga
     5761 attacatatt cattttcttg ctcagcaaaa agaatagtct ctttcttttt atacgttttt
     5821 ttaacaagct tctttttaat atcttcattc ataaaatcaa ttaaatgcat attcatctct
     5881 ccttaccaaa tctttgatta aattatatca tctttcaatt agttaggtaa gatagtaaaa
     5941 atatatttac atagaaacta ttccattatt attttccagt tgtcattttt ctgcaaaaac
     6001 ttatcactgt cacgactgga gataccagta aggaatgtta ggatatcaat cgctaaactt
     6061 tcagaatcct ttttacggct caaaatgacg taatggtcaa gcaatccttt gttttcatca
     6121 tcactggtta aattgacaat gtttatctca tgggctattt ctggtagcgt ttctttccat
     6181 ttgccgcgtt ttgctttagg gtcaactatg accgcttgtc cgccgaatag taccgcatag
     6241 taaacaagca tattgttact gaataattta ccaccaccca atgaaccgat aaacgcagac
     6301 gctaacgcat tggtaataga accctttacc ccttgactag caagggcagg ttttagatag
     6361 acattctttc cagtgtccag attgtagcca agatagatat cctcatgttc gccaagggtt
     6421 tgtgtcgctc caaaaccaag tccagccaaa aaatccgaag tgacatattg aatataatca
     6481 ttgatgtaac gtttgctgac aggaataaat tcgccatgca atcccaacat atccccaaag
     6541 ggacgcacga gcttgattga taagtcgtcg taaaagtctt tgacttcatc acaacgcctt
     6601 tttagctcgt caagatcctt tgtagataca cggacaacat agctaagttt atacatagat
     6661 tctttacagt taaaagtctc tttttaaaaa aatgtataaa ttataaatca aaatatagat
     6721 actatcaatg acccactagg tgcaaaaagc attgatatgg ttaaattatc agacgctaaa
     6781 agctgggcta tccgaatgag tgaagatggg tgtgcttata aatccattga caattataag
     6841 cgctcactga aagcgtcgtt tttcatggca attcaagacg actgtattag aaagaatcca
     6901 tttaattttt agttaagtga tgttttggaa gatacaacag aaccaaaaat cgctctaaca
     6961 ccagaacagg aaatgggctt attatccttt atggggagcg ataagactta ttataaatat
     7021 tatgatgatg ttgttatcct cttagaaaca ggactacgca tttctgaatt atgcggtttg
     7081 actttagaat tagatatgaa aaataaagcc attatggtag accatcaatt gttgagtgat
     7141 actaagattg gctattatgt agaagttcca aagaccacac agggtaagcg agaaattcca
     7201 atgactgaaa gagcttatca atcatttgaa cgtatcgttg aacggcgtaa gaacgctaaa
     7261 gcagaaccaa tcattgttga tggttaccag aacttcctat ttcttaaaca agatggatta
     7321 ccaaaacaag caactcatta tcaaagcatg ttaagagcgt tagtcaagaa gtataacaag
     7381 acccatgagg acaagctacc aaagattacg ccacatacct ttaggcatac actctgtaca
     7441 aatatggcta acaaaggaat gagtactaat atattgcaat atattatggg gcataaaaac
     7501 attactatga cgcttggcta ttatgcacat ggttcattta gttctgcgag agctgaaatg
     7561 gaacggttat aatcctagta gtatgactag agtttactac ttatttacta cttttgatgg
     7621 cattcttata cggttaaatg ccaacttatg caaagtatct tccaaaaaga aaatgtcgat
     7681 actccttgta gatacaggat atatcgacat ttaccaactt atgaaaagat aatcaaattt
     7741 aatataagtt tttcaaataa aaagatacta aattcttttt agagaatcta tataacatta
     7801 cttaagcttg gttggggtat aaacaattga gtagctactt ttgtatggtg ttcaacttta
     7861 gtcaaaactc ttaaataatg caaatgattt agattcatta atattcaatc tcttcataag
     7921 tagtgaaatt cgagttattt ctgcataatt atactatgat ttatagatta attctattag
     7981 catccagaat aatattgttt atatgagtaa aatttaaaga atattgtgaa aattatagaa
     8041 tgttaaaata aatttaggta aaaaaaagtg tttgtatatt atagagtacc ttttctaaaa
     8101 tatgtgggat tgttttaaga attagaataa aaattatttt taaattagta tttttataat
     8161 gtatagtatt tttaatgtat aattaaattg tgcagaaaat agaatttaaa gtcctataga
     8221 atttctgatt atggaggaga atatgaaaag aaaagttcaa gtaaaaaata ttactattgg
     8281 agaaggtaga cctaaaattt gtgtaccaat tattgggaaa aataaaaaag atattataaa
     8341 agaggctaaa gagttaaaag atgcatgttt ggatattata gagtggcgag ttgatttttt
     8401 tgagaatgta gaaaatatta aagaagttaa ggaagttctc tatgaattaa gaagttatat
     8461 acatgatatc cctttattat tcacatttag aagtgtagta gaagggggag aaaaattaat
     8521 atcaagagat tattatacta ctttgaataa agaaatttct aatacaggtt tagtagattt
     8581 aatagatgta gagttattta tgggagatga ggtcatagat gaagtagtta attttgctca
     8641 taaaaaagaa gtgaaagtaa ttatatctaa tcatgatttt aataaaactc caaaaaaaga
     8701 agagattgta tctcgtttat gtagaatgca ggaattgggc gcagatttac ccaaaatagc
     8761 tgttatgccg caaaatgaaa aagatgtgtt agtgctactt gaagctacaa atgaaatgtt
     8821 taaaatttat gcagatagac caataataac aatgtcaatg tcaggaatgg gtgttataag
     8881 tagattgtgt ggtgaaatat ttggttctgc attgactttt ggagctgcaa aaagtgtttc
     8941 agcaccagga caaatatcat ttaaagagtt aaattcagta cttaatctat tacataagag
     9001 tattaattaa attaattata tagaaatatt agaaggtatt ttatttttga agatataaat
     9061 taaatataaa aaacttttca gatagtaaaa tttaaattgg gcaattatat ctgaaaagca
     9121 actatttagt gtgtattttg aaagtgatat agaaaatctt ataaatcaac tatggcatat
     9181 ttaaaatatg ccattaaaac ctactagaca ttagattata gatggtatac tagcatttct
     9241 attatttata gatagtaagt tttcataata actgttttat ctaaagtaga agatatattt
     9301 gtattatgta tatttgtcat tatttttttg taattatgta tattaatggt tatatatgta
     9361 atataatatt atcactctat tttttgtata ttgtacatta caacatttat atctatcatc
     9421 atcaattaca gtagaatgta tgggatactt attttcactt aaccaatatt tttgcatatt
     9481 ctttgtccaa gactttggaa acttcaatac ttttttgttt attataacat cctcatcttc
     9541 aaaaatatta acttctcttt ctatttttat ttttctgttg tatatcttat tgatagattc
     9601 tttgtcgagt tttatgtccc tatacatatc agggcaatag caacaaacat aatttctttt
     9661 ttttcgacgt ttaaatttca caactttctc tatgctaatt tctaattttt ttgtaccatc
     9721 ttttataaat ttaatatctt ctatgttctc gcttgaaaaa atttctgtca atcttaaagt
     9781 atctacagtt tctctaatta tttgcttttt ataagaagag aatccatatc caaaagaaag
     9841 gtttaattta ttagggatgt agccattttt atatttaaac atcttaattt tttccaattc
     9901 agcattatct ttaaatttca acttttcata cctaaaagtt actttgctaa aaagagtata
     9961 ttctacatca atatattctt ttgcaatctt aaatttatcg ctaccttcaa tcacaatcat
    10021 agcctatctc caatcgtttt atattaaaat aaggccatag aacatggtct aatagtactc
    10081 attagcacta taagacaatg ttaacacaaa aagacaaaaa aaggttattt atttcaaata
    10141 accttttttt ttatataaaa tataaagaat tatattttat tcttttttat gatgtctata
    10201 atctgtgata tcagatttag ttctcttgaa tttaagtctt ttaactcttc atttatatca
    10261 ttttctaaat atgtttttcc agtggaagta atatctttta taagaacatc tgcagaaata
    10321 tttaatatat ttacaaattt tatgaatgtt ttaagacttg gattcttttt accactttcg
    10381 atttgagtta tataccaagg cgatactcca accatatttg caaattcttt tgaagttaaa
    10441 tttgcttttt tccgttcttc tttaagtctt ttacctatat aattcattat tgttactatt
    10501 tccctcactt atatttcttt gtatttaatg atgcacttta ttaactctag cattgcaatt
    10561 tgttcttttt cagttaattt attaatcatt tcataacatt ctaaaggtac agagttatca
    10621 acgccttctg ttgtaataat atttgcaaat aacaattcaa gtggtatgtc taaagcagta
    10681 gcaattttca ttataatatt gatagatgta tttgtctcag ctctttcaat ctgaccaata
    10741 tatgttggat gtaaacctgc cttttctgct agaaactctt gactatatcc caattttgtt
    10801 ctatagactt ttattctatc tcctattatt tttcctatat ttgccaatta ttatccctcc
    10861 actttagatt atattcatag tttaagttgt tttatataga ctatttatac ttttttagtc
    10921 taaatataga ctatatatgt ttttatactg aaataagtgc tatttatttt tgtatagtct
    10981 gtatctacaa taaacaaata tggataaatc atatttttaa ttagagaaat attttcataa
    11041 tt
//
LOCUS       DAMKNB010000103        10764 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.109, whole genome shotgun sequence.
ACCESSION   DAMKNB010000103 DAMKNB010000000
VERSION     DAMKNB010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 10764)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10764)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10764
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.109"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            145..1344
                     /locus_tag="PC494_003170"
     CDS             145..1344
                     /locus_tag="PC494_003170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanyl-tRNA editing protein AlaX-L"
                     /protein_id="HDF3913645.1"
                     /translation="MEKLYYTNQYIRDFTAEIIEIKEVENKYHVLLDKTAFFPGGGGQ
                     FGDLGKIENDDVINVYEDGKKIYHVLDKKPIKIHKVKCSIDWDRREDGMHQHFGQHVL
                     SGCFFKTFNANTTGFHLGNEYSTVDIEGNLEEDKIREIELFANEIIRQNIQVETLLPT
                     KKELKKIWLRRDLPNTDEEIRVIKIGDLDTNACCGVHPKSTGELRMIKIKKWEKHKSS
                     TRIEFLAGKRAVDEVLKRDIYLTKICRYLSCSEEDAINGIVNLNSKVEEALIKKRRLE
                     EVVSTYQVKEMIEKANKVGNISVIKKIYDDEDLKYVNKIANKIAEYENSIALLAVKFN
                     DKINLVFACSKNLKDINMGVLLKDAISLIDGKGGGSKVLAQGGGKNNGNLEATLDYAF
                     MKIEKTL"
     gene            1396..1899
                     /locus_tag="PC494_003171"
     CDS             1396..1899
                     /locus_tag="PC494_003171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDF3913646.1"
                     /translation="MEQQKDYIELYENEELIEIREARMDDLDTIAKFNYNLAKETEGK
                     ELDMDVLTKGVKALLLDERKGKYHVYTVFDKVVAQIMYTYEWSDWRNGNFLWIQSVYV
                     DKEYRRKGIFNYLFNYIKNICDKDENIVGMRLYVEKENINAKATYESLNMYECDYNMY
                     EYEVVHS"
     gene            2006..2323
                     /locus_tag="PC494_003172"
     CDS             2006..2323
                     /locus_tag="PC494_003172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3913647.1"
                     /translation="MGVLKGMFYVFLFLDLVSIFCFFFNKGKIASNKIVFNAIGVLTF
                     VLCFMLFSYYPNNNLIGKFIASLFFIFGVAGVMLKEKNFLYARLLLTVVIVFSTLRLF
                     VIQ"
     gene            2481..3440
                     /locus_tag="PC494_003173"
     CDS             2481..3440
                     /locus_tag="PC494_003173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HDF3913648.1"
                     /translation="MIESKKSEKLLLSIIYIIFLVYILMIIRIILFRDVPIYAIFKGT
                     FRNVNLIPFYTIYQFIVDSNLDFMKATVNIIENIGIFIPMGIFLPIVCKNLNKKTIII
                     VIILVSLAFELTQYIFALGSSDIDDVILNSLGGIIGINIYINMNKLFPSDINRFKAII
                     GTSLVLGVIGLGVISKNYHNLLTFKFRPDRKISKILIEENREIIKDINKDTVDIVGTF
                     ESFKKGIITIKAGSNNKVKRPENLIDSDGNIRIYLNENTKLVSYIITKESKMDIVKYE
                     EFDVKNLDLLRRYDTINVWIDKENQPKDKHGIMASKLLIGLYE"
     gene            3555..4340
                     /locus_tag="PC494_003174"
     CDS             3555..4340
                     /locus_tag="PC494_003174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3913649.1"
                     /translation="MEIIKYILYFFIYSFLGWTVESIGCSIASKRIINRGFLNGPICP
                     VYGFGAVIVISLLGRFNNVVIVFLLGMILTTILEYFTGFILETLFHAKWWDYSDRKFN
                     IKGRVCLKNAIYFGVMSVLIIRFIHPFIKYFVSIIPYRILISMAIITTLWTILDLIVT
                     IITLKKLDIKLNLLDDIITDLNDINVKLDKFDRGEIQALFKTINNDELEVREKINKIN
                     SKLDRIESNIILQKRVIKAFPHIKHKKQQEQLEHFKKIINEKR"
     gene            4632..5951
                     /locus_tag="PC494_003175"
     CDS             4632..5951
                     /locus_tag="PC494_003175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class III-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HDF3913650.1"
                     /translation="MSEITSQMISTEEKKYVAKTQKIPYYPVAFKSGDGAMLYDYEGN
                     EYVDFLASAGSANVGHGNKEISQAVKEQMDDITQYTLAYFHSDPPVKLAEKLVEIAPG
                     DNDKKVLYSATGSACIDAAIKLARGYTGRTKIISMCESYHGSTYGAISISALSTNMRR
                     KMGPLLPEVYHFHYPDKNRTAKECLDEIEYAFAHYLPAEEVAAIFIEPIAGDAGIIVP
                     PVEWVQGLSKICKENGILLVSDEIQQGMGRTGKWFGIENFGVEADLIVLGKSVGGGLP
                     LGAVVGRTEIMQSLDAPAHLFTLAGNTTVCVAALKSIEIIEKENLLQKSIEMGDYIKA
                     GFEKLKEKYDIIGEIRGIGLSIGVDIVKGKGSNEKHPDATAKICYRCIQTGLIMIFLG
                     QSTLRVQPPLVITKEQVDKAMNIIDSAIDDYLNGRIGDEVYEVTQGW"
     gene            complement(6026..6454)
                     /locus_tag="PC494_003176"
     CDS             complement(6026..6454)
                     /locus_tag="PC494_003176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3913651.1"
                     /translation="MKDNNNTNKTIQFGEKKASLENNIQKNKNIKLDNTHKVIPYPKN
                     RKKDDKKKGNKKKNTNTSKVNKNNYGHSFFNNKYKYKRKPYVIALYTVILILLAILII
                     TKLTDSTNKGNYSRNTVSDTHKNDIRNIVFNESNNFLICG"
     gene            complement(6545..7921)
                     /gene="hydG"
                     /locus_tag="PC494_003177"
     CDS             complement(6545..7921)
                     /gene="hydG"
                     /locus_tag="PC494_003177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="[FeFe] hydrogenase H-cluster radical SAM
                     maturase HydG"
                     /protein_id="HDF3913652.1"
                     /translation="MFINHELINSLLEDAKNSTSDDIEKVLDKADRREKLSYKDIATL
                     LEVEDKKQLDRLFSIAGQIKNEIYGNRVVLFAPLYVSNYCVNECVYCGFSKCNKFKRK
                     KLTMEEIKEEVKILEKMGHKRLALEAGEDPKNCDINYILDCLDAIYSTYNENGNIRRV
                     NVNIAATSVDEYKLLKEKGIGTYILFQETYHKPTFIKMHGQSIKNDYYYHLTAFDRAM
                     EAGVDDVGAGVLFGLSDPKFEVLGLMMHNEHLEEKFGVGFHTISFPRLKKAEGMSLED
                     FPHLVSDDMFKKIVAITRLAVPFTGIIMSTRETAEMRNELLKYGVSQISAGSLTGVGG
                     YKAYEDGDNTEQFEVGDHRSPVEVLKELITDGYIPSYCTACYRKGRTGDRFMSLAKSR
                     QIHNVCTPNALTTLNEFLIDYGDEELKIMGKKLIAEEIGKIEREDIRNIVSNNMTALE
                     RGERDLYL"
     gene            complement(7922..9007)
                     /gene="hydE"
                     /locus_tag="PC494_003178"
     CDS             complement(7922..9007)
                     /gene="hydE"
                     /locus_tag="PC494_003178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="[FeFe] hydrogenase H-cluster radical SAM
                     maturase HydE"
                     /protein_id="HDF3913653.1"
                     /translation="MTKNKIKYFIDKLYSINSLSFDELLYLIENIDNEEYNFEQNLRN
                     YLYKQASDMRNKHYGNRVYLRGLIELTNYCKNNCYYCGIQSSNKNIIRYRLSLDEILE
                     CCDIGYKIGYRTFVLQGGEDAYFTDDKICEIVSSIKNKYEDCAITLSLGEKSYDSYKK
                     YFLCGADRYLLRHETATDSHYKKLHPPNIELRTRKECLKNLKEIGYQVGAGFMVESPF
                     QNNEDLVRDLLYLKELNPHMVGIGPFIPHHDTIFKDYKHGDLEKTLLMLSITRLLLPK
                     VLLPATTALASINPSGRNAGLLAGCNVIMPNLSPQEFRKQYSLYDNKAFTGQEACEYH
                     QSLEENIKSLGLEVDYSRGDNIEWRRL"
     gene            complement(9043..10251)
                     /gene="hydF"
                     /locus_tag="PC494_003179"
     CDS             complement(9043..10251)
                     /gene="hydF"
                     /locus_tag="PC494_003179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="[FeFe] hydrogenase H-cluster maturation GTPase
                     HydF"
                     /protein_id="HDF3913654.1"
                     /translation="MSLNSTPQSVRVHIGLFGKRNAGKSSIINAITNQSAAIVSDIAG
                     TTTDPVFRPMEILPIGPCVLIDTAGLDDVGELGELRIGKSLDVLEKTDIALLVVDCQI
                     GISQEDLSLIEKFNDKNIPHILILNKIDTIKNQSEILNLTKNKVKCPVVSVSSTDKIG
                     IENLKNEIIKVLPKDSTEFKLVSDLIEPNDLVVLVVPIDKAAPKGRLILPQQQVIRDI
                     LDNGAISIVTKEDSLKETLSNLGKKPKLVITDSQVFPQVDKDTPKDIPLTSFSILFAR
                     QKGDLKELINGAYALENLKDGDKILMAEGCTHHRQTDDIGTVKIPNMIRKKTGKNITF
                     EFSSGVSFTEDINKYALVVHCGACMMNRAGMLSRIEKAKSFNVPIVNYGVLIAYVKGI
                     LERSLELFNY"
     gene            complement(10266..10517)
                     /locus_tag="PC494_003180"
     CDS             complement(10266..10517)
                     /locus_tag="PC494_003180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003361768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-only hydrogenase system regulator"
                     /protein_id="HDF3913655.1"
                     /translation="MKKVAVISAILEEPKECQFKFNEVVSGFKGIIKGRMGIPCEEEG
                     VSIVCIAVVGEMDTINSLTGKLGNIPHVSVKTSISKKEV"
BASE COUNT         3976 a         1298 c         1676 g         3814 t
ORIGIN      
        1 atatctatat gttaaaatat agtagaagat gttagtaaat aataggatga gttctatttt
       61 aatacaatta aattaagctt agtttgaaat ttgtatctaa aaagtaaagt aatctagaat
      121 taagaaaatg gagatagaat tataatggaa aaattatatt atacaaatca gtatataaga
      181 gattttacag cagaaataat tgaaataaaa gaagtagaaa ataagtatca tgttttatta
      241 gataagacag ctttttttcc tggtggagga ggtcagtttg gagacctggg aaaaatagag
      301 aatgatgatg taataaatgt gtatgaagat ggaaaaaaaa tataccatgt attagataaa
      361 aaacctataa agatacataa ggtaaagtgt agtattgatt gggatagaag agaagatgga
      421 atgcatcaac attttggaca acatgtattg tctggatgtt tttttaaaac ttttaatgca
      481 aatacgacag gttttcattt gggaaatgag tatagtacag tagatataga aggtaattta
      541 gaagaggata aaattagaga gatagagttg tttgccaatg aaattattcg tcaaaatata
      601 caagtagaga cattacttcc aacgaaaaaa gaactaaaaa agatttggtt aagacgtgat
      661 ttgccaaata ctgatgaaga gataagagta ataaaaatag gtgatttaga tacgaatgca
      721 tgttgtggag tgcatccaaa atcaactggt gaattgagaa tgataaaaat aaagaaatgg
      781 gaaaaacata agtcaagtac aagaatagag tttctagcag gtaaaagggc agtggatgaa
      841 gtattgaaga gggatatata tttgactaaa atatgtagat atttaagctg tagtgaggaa
      901 gatgctataa atggtattgt aaatctaaat agtaaagtgg aagaggcttt aattaaaaaa
      961 agaaggcttg aagaagtagt atctacatat caggtcaaag aaatgattga aaaagcaaat
     1021 aaggttggca atatttcggt cattaaaaaa atttatgatg atgaagattt gaaatatgta
     1081 aataagatag caaataaaat tgcagaatat gaaaatagta ttgcattatt agctgttaaa
     1141 tttaatgata aaataaattt agtttttgca tgttctaaaa atttaaaaga tattaatatg
     1201 ggagttttat taaaggatgc aataagtctt atagatggca agggtggtgg aagtaaagta
     1261 ttagctcaag gaggaggtaa gaataatgga aatttagagg ctacacttga ttatgcattt
     1321 atgaagatag aaaaaactct ataaatatat tatataaaaa accttagtag ataaaataga
     1381 tatggaggaa taagtatgga gcaacaaaag gactacatag agttatatga aaatgaagaa
     1441 ctaatagaga taagagaagc acgtatggat gatttggata caatagcaaa atttaattat
     1501 aatttggcta aagaaactga aggaaaagaa cttgatatgg atgttttaac taaaggtgta
     1561 aaagcattgt tattagatga gagaaaagga aaatatcatg tatatacagt atttgataaa
     1621 gttgttgcac agattatgta tacatatgag tggagtgatt ggagaaatgg aaatttcctt
     1681 tggattcaga gtgtatatgt agataaggaa tatagaagaa aaggtatctt taattattta
     1741 tttaattata taaaaaatat atgtgataaa gatgaaaata tagttggaat gagattatat
     1801 gtagaaaaag aaaacataaa tgcaaaagca acatatgagt ctttaaatat gtatgagtgt
     1861 gattataata tgtatgaata cgaagtagta cattcgtaat ataaatttgt aatactgtta
     1921 tacttatgtt ataaagtatt gattatattg acgattatat gaaataaact ggatattata
     1981 attagaattt ttagggggta taaaaatggg cgttttaaaa ggaatgtttt atgtattttt
     2041 atttttagat ttagtgtcaa tattctgttt ctttttcaat aaaggaaaaa tagcatctaa
     2101 taaaattgtg tttaatgcaa taggagtact tacatttgta ctttgtttta tgctttttag
     2161 ttattatccc aataataatc ttattggaaa atttattgct tctctatttt ttatatttgg
     2221 agttgcagga gttatgttga aagaaaaaaa ttttttatat gctagacttc ttttaactgt
     2281 agttatagtt ttttctacat taagattgtt cgttattcaa taaaatgtat ttgtatgaaa
     2341 atttattaaa gtctacacat ttaagtgtag gcttttttga ttttttgttt gaaaattaag
     2401 gaaattttaa ggaaatttta aaatcgtctt aaatatttat tgatatactt aaaatattaa
     2461 tagcgaaagg agacttatca gtgatagaaa gtaaaaagtc agaaaaattg ttactgtcaa
     2521 ttatatacat aatatttttg gtatatattt taatgattat aagaataatt ttatttagag
     2581 atgtaccaat ttacgctatt ttcaagggaa cgtttaggaa tgtaaattta attccatttt
     2641 atacaatata tcaatttata gtagatagta atcttgactt tatgaaagct actgtaaata
     2701 ttatagaaaa tataggtata tttattccta tgggaatttt tttacctata gtatgtaaaa
     2761 atctaaataa aaaaactata attatagtaa ttatacttgt tagcctagca tttgaattaa
     2821 cacaatatat ttttgctctt ggaagtagtg atatagatga tgttatttta aattcattag
     2881 gtggcataat tggaattaat atttacataa acatgaataa attatttccc agtgatatta
     2941 acagatttaa ggctataata ggtactagtt tagttttagg agttatagga ttaggagtta
     3001 tttctaaaaa ttatcataac ttactaactt ttaaatttag acctgataga aaaatatcaa
     3061 aaatattaat tgaagaaaat agggaaataa ttaaagatat aaataaagat acagtagata
     3121 tagttgggac atttgagagc tttaaaaaag gaataataac tattaaagca ggttctaaca
     3181 acaaagtaaa gagaccagag aatttaattg attctgatgg aaatataaga atttatttaa
     3241 atgaaaatac aaaattagta tcttatataa ttaccaaaga atcaaaaatg gatatagtta
     3301 aatatgagga atttgatgtg aagaatttag atttattaag gagatatgat actattaatg
     3361 tttggattga taaagaaaat cagccaaagg ataaacatgg tattatggct agtaaattat
     3421 taattggatt gtatgaataa aatattaaac aagaataaaa gaataacaaa tataaaaaac
     3481 gaaaaaacta tttctataat tatttttacg ttgtgcataa aataagaaca ttagtgaagg
     3541 agtagagata aattatggag ataataaaat atattttgta cttttttata tattcatttt
     3601 taggatggac agtagaaagt ataggatgtt ctatagcaag caaaagaata atcaacagag
     3661 gttttttaaa tggtccaata tgccctgttt atggttttgg agcggtaatt gtgatatcac
     3721 tattgggaag atttaataat gtagtaatag tatttctatt aggaatgatt ttaactacga
     3781 tactagaata ttttacagga tttattttag aaaccttatt tcatgctaaa tggtgggatt
     3841 attctgacag aaaattcaat ataaagggta gagtatgttt aaaaaatgca atatactttg
     3901 gtgtaatgtc tgttttaata ataagattta tacatccatt tataaaatat tttgtaagta
     3961 taattccata tagaatatta atttcaatgg ctataattac aacactttgg actatacttg
     4021 atttgattgt tactattata acacttaaaa aattagatat aaagttaaac ttattagacg
     4081 atataattac agaccttaat gatataaatg tgaaattgga taaatttgat agaggagaaa
     4141 tacaagcttt atttaaaaca ataaataacg acgaattaga agttagagaa aaaataaaca
     4201 aaataaatag taagttggac cgtatagagt ctaatattat tttacaaaaa agagttataa
     4261 aagcttttcc acatataaaa cataaaaaac aacaagagca actagaacat tttaaaaaaa
     4321 ttattaatga gaaaaggtaa ttatacaatt taatgaagac gaatagaata atggtattta
     4381 taagatgatt ttcagaggac tctataaaaa tagaatagag tcctttattt tttgaaaaat
     4441 aatgtttatt tgataaaaat aaaatatatt gtttctgaat aacaaatatt ttgaaaatta
     4501 taaaaacata tattgacaat ttgtgtcaaa aatactaaca ttaagtatat aaagaatttt
     4561 atatgagaat atctttataa atcgcaataa ttttaaaaca taaatttatt taaagagggg
     4621 atgatttgcc aatgagcgag ataactagtc aaatgataag tacagaagaa aaaaaatatg
     4681 ttgctaaaac tcaaaagata ccttattatc cagtagcatt taaatcaggt gatggtgcaa
     4741 tgctatatga ttatgaaggt aatgaatatg tagatttttt agcaagtgca ggctctgcaa
     4801 atgtaggtca tggtaataag gaaatctcac aagcagttaa agaacaaatg gatgatataa
     4861 cacaatatac acttgcatat ttccatagtg atcctcctgt aaaattagct gagaagcttg
     4921 tggaaatagc ccctggagat aatgataaaa aagtactata cagtgcaact ggttctgctt
     4981 gtatagatgc tgctataaaa ttagcaagag ggtatactgg aagaacaaag ataatatcta
     5041 tgtgtgaatc ttatcatgga agtacttatg gagctatatc tatatctgct ttaagtacaa
     5101 atatgagaag aaaaatgggt ccattgttac cagaagttta tcacttccat tatcctgata
     5161 aaaatagaac agctaaagaa tgtttagatg agatagaata tgcttttgca cactatctac
     5221 cagcagaaga ggtagctgca atatttatag agccaattgc aggagatgca ggaataatag
     5281 tgcctccagt agagtgggta caaggtttaa gtaaaatatg taaagaaaat ggaatattac
     5341 ttgtaagtga tgaaatacaa caaggtatgg gaagaacagg taagtggttt ggtatagaaa
     5401 attttggtgt tgaagcagac cttatagttc ttggaaaatc tgttggaggt ggattacctc
     5461 taggagcagt tgttggaaga acagaaataa tgcaaagtct tgatgcacca gcacatttat
     5521 ttactttagc tggaaacaca acagtatgtg tggctgcttt aaaatctata gagataattg
     5581 aaaaagaaaa cttacttcaa aagagtatag aaatgggaga ttatattaaa gcaggatttg
     5641 aaaaactaaa agaaaaatac gatataattg gagaaataag aggcatagga ttatctatag
     5701 gagttgatat agttaaagga aaaggttcta atgaaaaaca tccagatgct acagctaaga
     5761 tatgttatag atgtatacaa actggattaa taatgatatt cttaggacaa tctactttaa
     5821 gagtgcaacc acctctagta ataactaagg agcaagtaga taaagcaatg aacatcatag
     5881 attctgcaat agatgattat ttaaatggta gaattggtga tgaagtatat gaagtaactc
     5941 aaggttggta aaataaatat taaatgaaaa taggagttat ctcaatttta gaaaattatt
     6001 tctgaaatga gataactctt ttaagttacc cacaaataag aaaattgttt gattcattaa
     6061 agactatatt tcggatgtcg tttttgtgag tatcagagac agtattacga gaataattac
     6121 ctttattcgt actatctgtt aatttagtta taattaagat agctaaaaga ataagaatta
     6181 ctgtgtataa agcaataaca tatggttttc ttttatattt gtatttgtta ttgaaaaaag
     6241 aatggccata attattttta tttactttag atgtatttgt attctttttc ttgttacctt
     6301 tctttttatc atcctttttt ctatttttag ggtaaggaat gactttgtgt gtattatcaa
     6361 gtttgatatt tttatttttt tgaatattgt tttccaggct agcctttttt tctccaaatt
     6421 gaatagtttt attggtattg ttgttatctt tcaatgttaa tctccctccc ttaaactttc
     6481 cctttagata atattactac taacctatgg aatatacaat aaataatata taagtaataa
     6541 aattttatag gtataaatct ctttctccac gctctaaggc agtcatattg ttagatacta
     6601 tgtttcttat atcttctctt tctatcttac ctatttcttc tgcgataagt tttttaccca
     6661 taattttaag ttcttcatct ccataatcga ttaaaaattc atttaatgta gtaagagcat
     6721 ttggtgtaca tacattatgg atttgtcgac ttttagctaa gctcatgaat ctatcgccag
     6781 ttctaccttt acgataacaa gctgtacaat aactaggtat atatccatca gtaatcagtt
     6841 ctttaagcac ctcaacaggg cttctatggt ctccaacttc gaattgttct gtattgtcac
     6901 catcttcata tgctttatat cctccaacac ctgttagaga acctgcacta atttgtgata
     6961 caccatattt tagtaactca tttctcattt cagcagtttc tctagtggac attatgattc
     7021 cagtaaaagg aacagctaat ctagttatag ctactatttt tttgaacata tcgtcagaaa
     7081 ctaagtgagg aaaatcttct aagctcatac cttcagcttt tttcaatcta gggaaagata
     7141 tagtatggaa acctacacca aatttttcct ctaagtgttc gttgtgcatc ataagtccta
     7201 gaacttcaaa tttagggtca gataaaccaa ataaaactcc tgcaccaaca tcatcaacac
     7261 cagcttccat agctctatca aaagctgtta aatggtaata atagtcattt tttatagatt
     7321 gaccatgcat ttttataaat gttggtttgt gataagtttc ttggaataat atataagttc
     7381 ctattccttt ttcttttagt aatttatact catctacact tgtagctgct atgttaacgt
     7441 ttacccttct tatatttccg ttttcattat atgttgaata aattgcatct aagcaatcta
     7501 agatgtaatt tatatcacaa tttttagggt cttcaccagc ttctagagca agtcttttat
     7561 gacccatttt ttctaatatt ttaacctctt cttttatctc ttccatggta agtttttttc
     7621 ttttaaattt gttgcattta ctaaaaccgc aataaacaca ttcatttaca cagtagtttg
     7681 atacataaag aggggcaaat aaaaccactc tattaccata tatttcattt tttatttgcc
     7741 cagctatact aaataatcta tctagttgtt ttttatcttc cacttcaaga agtgtagcta
     7801 tatctttata actaagtttt tcccttctat cagccttatc aagtaccttt tcaatatcat
     7861 cagaagttga attttttgca tcttctaata aagaattaat aagttcatgg tttatgaaca
     7921 tttacaaacg cctccattca atattatcac cgcgagaata gtcaacttca agtcctaatg
     7981 acttgatgtt ttcttctaaa ctttggtgat attcacaagc ttcttgacca gtaaaggctt
     8041 tgttatcgta aagagaatat tgttttctaa attcttgagg agaaaggttt ggcataatta
     8101 cattgcaacc agctaaaaga cctgcatttc taccactagg gtttatagat gccaaggctg
     8161 ttgtagcggg taataaaact tttggaagta gaagtcttgt aattgaaagc ataagtaatg
     8221 tcttctctaa atctccatgt ttataatcct taaaaattgt atcatggtgt ggaatgaaag
     8281 gtcctattcc aaccatatga ggatttaact cttttaggta taataaatca cgaacaaggt
     8341 cttcgttgtt ctgaaatggt gattcaacca taaatccagc acctacttga taaccaattt
     8401 ctttaaggtt ttttaggcat tcttttctag ttctaagctc aatgtttggc ggatgtaatt
     8461 ttttataatg actgtctgta gcagtttcat gtcttaaaag atatctatct gcaccacata
     8521 aaaagtattt tttatacgaa tcataactct tttctcctag tgatagagtt atggcacaat
     8581 cctcatattt attttttata cttgaaacaa tttcacatat tttatcatca gtaaaatatg
     8641 catcttcacc accttgcaaa acgaatgttc tgtatcctat tttataacct atatcacaac
     8701 attcaagtat ttcatcaagt gaaagcctgt atcttatgat atttttatta gaagattgta
     8761 ttccacaata gtagcaatta tttttacaat agtttgtaag ctctataagt cctctcaagt
     8821 agactctatt tccataatgt ttatttctca tgtcgctagc ttgtttataa agatagtttc
     8881 ttaaattttg ttcgaagtta tattcctcat tgtcgatatt ttctattaaa tatagtagtt
     8941 catcaaaact taatgaatta atgctgtaaa gtttatctat aaagtattta atcttatttt
     9001 tagtcatatt caaatatgta attattaagt atagttaaat ttttaataat tgaaaagttc
     9061 aagtgatctt tccaaaatac cttttacata tgctattaag acaccatagt ttacaatagg
     9121 tacattgaaa gattttgcct tttctattct agataacatt ccagctctat tcatcataca
     9181 agctccacag tgaactacaa gggcatattt atttatatct tcagtgaagg atactccaga
     9241 actaaattca aaagtaatgt ttttgccagt tttctttcta atcatattag gaatttttac
     9301 tgttccaata tcatcagttt gtctatgatg ggtacatcct tcggccatca agattttatc
     9361 accatctttt aaattttcta aagcataagc tccattaatc aattctttaa ggtctccctt
     9421 ttgtctagca aacaatatag aaaaagatgt aagaggaata tcttttggtg tatctttatc
     9481 tacttgtgga aatacttgag agtcagtaat aacaagtttt ggttttttgc ctaaattaga
     9541 tagagtttct tttaaactat cttcttttgt aactatagaa attgcaccat tatccaaaat
     9601 atctcttata acttgctgtt gaggaagtat aagtctacct tttggagctg ctttatctat
     9661 tggaacaact aaaacaacta aatcatttgg ttcaattaaa tctgatacca atttgaactc
     9721 agtgctatcc ttaggcaaaa cttttattat ttcatttttt aaattttcaa ttccaatttt
     9781 atctgttgat gagacagaaa caactggaca tttaacttta tttttagtta agtttaaaat
     9841 ttctgattga ttcttaatag tatcaatttt gttaagaatt agaatatgag ggatattctt
     9901 atcattaaat ttttcaatta gtgacaaatc ttcttgtgat ataccaattt ggcaatccac
     9961 tactagtaaa gctatatctg tcttttctaa aacatctagt gatttaccta ttctaagttc
    10021 accaagttca ccaacatcat caagaccagc agtatctata agaacacaag gtcctatagg
    10081 aaggatttcc attggtctaa atactgggtc tgtagtagtt ccagcaatat ctgagactat
    10141 tgcagcactt tgatttgtta tagcatttat tatgctagat ttacctgcat ttcttttacc
    10201 aaagagacct atatgtactc ttaccgattg tggagtagaa tttagactca tttgtactca
    10261 ccaccttaaa cttctttttt tgatatacta gtttttacag atacatgagg tatgttgcct
    10321 aatttaccag tcaaactatt aatagtatcc atttcgccaa caactgctat acatacgatt
    10381 gagacacctt cttcttcgca aggaatgccc attcttcctt taataatacc tttaaaacct
    10441 gatacaacct cattgaattt aaattgacat tcttttggct cttccaaaat agcacttata
    10501 actgcaacct ttttcataaa tatcctccta actcagaaaa tatgtcttaa acaaatccaa
    10561 aatcaaaaaa cttttctttg taaagaaaag tttctacaaa agaaaagtta ttaattacac
    10621 aagtataatg tgctatatta aactatttcc ttacagatta gataactctt ttctggtagg
    10681 gttagcttgt aaaaatttaa tttaacaaca agtaactgaa gaaaattttt atacaattta
    10741 tataaattat aataaaaatt aact
//
LOCUS       DAMKNB010000104        10677 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.110, whole genome shotgun sequence.
ACCESSION   DAMKNB010000104 DAMKNB010000000
VERSION     DAMKNB010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 10677)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10677)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10677
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.110"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            158..1318
                     /locus_tag="PC494_003181"
     CDS             158..1318
                     /locus_tag="PC494_003181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF819 family protein"
                     /protein_id="HDF3913656.1"
                     /translation="MIETGFVYCSFLVVFVGVIFFMVDKLKWKVFDVINPMLLIYLGS
                     AILGSFGLFAQNEDVGTYQNIITVNFLPLMLVFLLIQCDLRKILKMGPKMLLSFFCAT
                     FTFMLGFVIAFIIFKNSMGADSWKILGAASGSWIGGSSNMIAAANALGVAEEGLSYAI
                     LMGSIGYTVWMSVCLMSVKFGPKFNKWTKCDTSFIDEVTSKLEKENKDNTAPTFVELM
                     ILLSVGFGVASFAQIVSKILPTSGILNETMWVVLVASTVSILLGMTKISKLKGSTLVG
                     NVFMYLLLAATGSKANFFGLSEAPVYIMFGLVVVLVHAISFIGLAKLFKLDLFTCEVG
                     SIANIGGVTTAPMIAGVHNPVLIPVGVLMGLLGNIIGTYCALMVTQILHMLA"
     gene            1660..1821
                     /locus_tag="PC494_003182"
     CDS             1660..1821
                     /locus_tag="PC494_003182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3913657.1"
                     /translation="MIIPSRRIQDITLTNLKNGEVTLIELDEIYKKMGFLFVVSEGKL
                     KKIKKENHH"
     gene            2014..2643
                     /locus_tag="PC494_003183"
     CDS             2014..2643
                     /locus_tag="PC494_003183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HDF3913658.1"
                     /translation="MKIVTYNIHKGMDSNNRLTLTKMGLYLKQLDCDVICLQEVLYPQ
                     FLALKAVLNMDGVFATNVKKVNMIYGICTFTTSKMLNSNHFFLTSKKEQRGALCITID
                     AYGRIINVINTHLGLDRQERAKQLDEIIDYRNRLVGIVILCGDFNEKNVFLSMFNDMA
                     ISLNKSYLPTFEKSNSRIDYIFVNKNTELKGYTVEKIYLSDHYPVIGYI"
     gene            2882..4141
                     /locus_tag="PC494_003184"
     CDS             2882..4141
                     /locus_tag="PC494_003184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanW family protein"
                     /protein_id="HDF3913659.1"
                     /translation="MGRRTTRVSRLGKEKKRSVLIVLAALVLIMGGFTYFFNSKFLYN
                     GKIAKNVYIEGVNVSDMTKAEALKAITDKYTPEDLNLAYDGKKYTISPKDIDLKYDTE
                     DVVKDAYESTKKGSYFQNLKKYIDIRVNKANMKIKAEYDEAKLSSKVSSIADSINVKM
                     KNASISVGSGGLSYTDSVVGREFDLAANKESIYNMIKNKEHKTLELKVNLQKPDITTE
                     QVKTVNSVIGQYSTTYSQAVEGRSYNVGLSARKTSDVLLMPGEEFSYNKLTGPSNKAN
                     GYKDAPVIVYGKLEQSAGGGVCQTSSTVYNAALLSGMEITQVTNHSSASTYVPKGRDA
                     TVSDGGLNLKFKNPYKHPVYIKNYAGGGSVSSVIYGNSGDKPNISIEVKQTGQNKYST
                     YRIFKDSSGKVIKKEHISNSSYKELKK"
     gene            4400..5395
                     /locus_tag="PC494_003185"
     CDS             4400..5395
                     /locus_tag="PC494_003185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein kinase"
                     /protein_id="HDF3913660.1"
                     /translation="MYEEVTWLNFIGNRYEVVNSDDVLEINKIYKARDVFYRKNVLIK
                     VIKHNNYICEDFVSNLIDESTALDEINSPYILKIIDVGIHCTEETTLYYVVSEDFNGI
                     GLDELILGNYLHLEAIVNIMIQVLKALEMIHRNHSYHGSLKSSSIIVDTEYNIKICDF
                     GITKANNGVNTRSYGNRRYLCPHQLCINYTDKESDFFATGLILFESIFKKLPFGESNS
                     EEKMLQSIDKGLDWNSIKAINGNTELINVIKRLLGRNNKYTRANDIIIDLSKVMYEKA
                     YIEVEDEKEEEQKQDKVIQVKKEYKSKMRKKLHKKLVVAGLAIVMISMIIISSII"
     gene            5641..6708
                     /locus_tag="PC494_003186"
     CDS             5641..6708
                     /locus_tag="PC494_003186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA ligase RtcB family protein"
                     /protein_id="HDF3913661.1"
                     /translation="MSNIKIIASNKCWIEDIARKQLEDISKLNGILRVVGLPDLHAGK
                     IPVGLAVETKNIIYPHIIGNDIGCGMTLFKTGVLKKKFKKDKWIKSLSKIKDLSDIEI
                     KNTYKEECPILNLGTIGSGNHFVEIQCISEIYNKEQFEQLKFSSDDIMMLVHCGSRNY
                     GEDILKKFYDKDGLEVESEKAIDYIKKHDNALMWAERNREAISKKIMQSIGTSGDVET
                     IFSINHNFVEKREDKFIHRKGAVSSERGAVIIPGSRGSLSYIVMPTENTEISLYSLSH
                     GAGRKWSRSVCKSRLKSKYSKDTIKQTKFKSQIICNDVNLLFQEAPEAYKNIEQIIES
                     LIEYELIQVVATMKPLITYKG"
     gene            7242..9152
                     /locus_tag="PC494_003187"
     CDS             7242..9152
                     /locus_tag="PC494_003187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HDF3913662.1"
                     /translation="MNSNTFERLQLNEVKELIKIHCVSSLGKNLIDKLTPSGNIGVVR
                     RKLAENKEARKIIENSNHIPLEGLFNAGSTIDKIEKGMIIEPVELVNIEDFLRGCRKM
                     KAFMLEKEFYSPTLSSYALNITECKSIEDEINYCIKSNKVDSNASKELKKIRRNIEIT
                     EGKIKDRLNKFITSTVNKKYIQEFIISKRNDRYVIPIKSSYKNEVNGTILDTSSKGNT
                     VFIEPISVSNLSTELTMLKADETIEEYKILSYLTELIFEKISQIKLNIEILSEYDMLF
                     AKAKYSQKIKGITPKINNNGYIKIIKGKHPLLTGDAVPLDFEIGKNYRSLIITGPNAG
                     GKTVTLKTVGLLTLMVQCGFDISAKEGSEFSVFEKVFVDIGDNQSIENALSTFSSHIK
                     NIAEIMSLSNNSTLVLFDEIGSGTEPNEGAGLAISLLEEFYKMGCITIASTHYGEIKK
                     FATLHPEFENAGMMFDKETLEPLYKLTIGKSEDSNALFISKKMGIKNRVLDRAKEYVI
                     DRNYNLDLVKRSKLQSNIEDKNSSEVILNYTDYNVGDKVKLLDEDDFGIVYKPMDKFN
                     NVEVLFNDNFVSVNIKRLQLSIKASELYPEGYDLDVLFTSFKERKLEKDIQRGSKKAL
                     KKIQKEIRENRK"
     gene            complement(9215..9838)
                     /gene="ytaF"
                     /locus_tag="PC494_003188"
     CDS             complement(9215..9838)
                     /gene="ytaF"
                     /locus_tag="PC494_003188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation membrane protein YtaF"
                     /protein_id="HDF3913663.1"
                     /translation="MIESILLVTSLCIDAFVTSFGYGVNKVKVPLYSNIIISVVCSAI
                     LAISLFAGTIVRDFLPQNITMLICFFILFLLGSARLIESFFKSYFKKKSIHSKNYNFN
                     MLDLKLNFNVSIEPDVLDTSKSKVLKSAEAFTLALALSLDGLAIGFGSGLVGVNYIQV
                     ILFSLISNIIAVLLGCLLGNMFVKNVNLNLSWLSGLILLVIGFMKIC"
     gene            10026..10670
                     /locus_tag="PC494_003189"
     CDS             10026..10670
                     /locus_tag="PC494_003189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF3913664.1"
                     /translation="MEQNNKVGNFGDLLKILLDEKELSMGELSKKSGIDKSTISRIAN
                     NKQKPNINHLEKMAIHLNINLEELLKASGYEFRNSNNQIFNADSDFSNFDDILGFANL
                     INDKNFNGNIEKELSKCKLYVQTDEGKKLLFDNFNKKIDSIEKQGQFTDRLRQMYADF
                     CTDGLTIKKYLLIGSMLLYFVISTDVIPDFVFPIGFMDDLVALNIVTKLLKNDK"
BASE COUNT         4366 a         1054 c         1756 g         3501 t
ORIGIN      
        1 aaatctttat taatatatgt caatagttag gtatatatgt atttaattag tatgatatag
       61 ataaaagtat ttattttaat tgtctattat ctgaaaaagt ctttacttag aaatcataaa
      121 aatcaaatta attaggaaaa gaaagggtgt gtataatgtg attgagactg gatttgtata
      181 ttgtagtttc ttggttgtat tcgtaggtgt aatttttttt atggttgata aattgaaatg
      241 gaaggtattt gatgttatta atccaatgct tttaatatac ttaggttcag ctatacttgg
      301 atcatttggt ttatttgcac agaatgaaga tgttggaacg tatcaaaaca taataacagt
      361 gaacttcctt ccattaatgt tagtgttttt gttaattcaa tgtgatttaa gaaaaatatt
      421 aaagatgggg cctaaaatgt tattatcatt tttctgtgct acatttacat ttatgcttgg
      481 atttgttata gcattcataa tttttaaaaa ttcaatgggt gcagattcat ggaaaattct
      541 tggggcagca tctggttcat ggataggtgg ctcatcaaat atgattgcag cagctaatgc
      601 tctaggagtt gcagaagaag gacttagtta tgcaatactt atgggttcta taggatatac
      661 agtatggatg tctgtttgtc taatgtctgt gaaatttgga cctaaattta acaaatggac
      721 aaagtgcgat acaagtttta tagatgaggt tacatcaaaa cttgaaaaag aaaataaaga
      781 taatacggca cctacgtttg tagaacttat gattttactt tctgttgggt ttggagttgc
      841 gtcttttgca caaattgtat ccaagatact tccaacttca ggtatactta atgaaactat
      901 gtgggtagta cttgttgcat ctacagtatc aatattattg ggtatgacaa aaatatcaaa
      961 gcttaaaggg agtacactgg taggaaatgt gtttatgtat ttactccttg cagctacagg
     1021 tagtaaagca aatttctttg gattgtcaga agcacctgtt tacataatgt ttggattggt
     1081 agtagtcctt gtacatgcta tttcatttat agggcttgct aaactattta aacttgattt
     1141 atttacttgt gaagtaggaa gtatagctaa tataggagga gtaactacag ctccaatgat
     1201 tgctggggtt cacaatcctg tattaatacc agtaggtgta cttatggggc ttctaggaaa
     1261 tattataggg acttattgtg ctcttatggt aactcaaata ttacatatgt tagcttaata
     1321 aaaatatggt ataaaattaa taatttaaat aagaaaagtc atttcaattt aagcagaagc
     1381 ttttactgaa atggcttttt tgtttgacaa gataatctat ttcaagaaga tgttttgaca
     1441 tatttagtgt ataatattgt aaaatttact aaaaacgaga tatatttaat ttttatattg
     1501 aatcgaacgt ctgtatgatg tataataaat atacagaacg aatgtttgta gaacgggtgt
     1561 tttttgaatt tattttaata atttatgaat atatatcaga atgcataaat atatttaaat
     1621 ataaagatta aaaagaattt aaaggagtgt tgataactta tgataattcc atcaagaaga
     1681 atacaagata taacattaac aaatttaaaa aatggtgaag taactttaat tgaattggat
     1741 gaaatataca agaagatggg atttttattt gttgttagtg aaggcaaatt gaaaaagata
     1801 aaaaaggaga atcatcatta gaaatgaatg aaataataaa tattataata gtttataaaa
     1861 cctaacttat gtagaatata aatacttaag ttaggttttt ttgtgataaa gtttataagt
     1921 actcaatttt ataagataaa taatggtctt aagtgaaaag taaataagtt taaattttag
     1981 taagtattat attgcataag aggtgatatt attatgaaaa tagtaaccta caatattcat
     2041 aaaggtatgg attcaaataa tagattaact ctaactaaaa tggggttata tttaaaacaa
     2101 ttggattgtg atgtaatttg tttgcaagaa gtattatatc ctcaattttt agctttaaaa
     2161 gctgttttaa atatggatgg tgtctttgcg acaaatgtaa aaaaagtaaa tatgatatat
     2221 ggtatttgta catttacaac atctaaaatg ttaaacagta atcatttttt cttaactagc
     2281 aaaaaagaac aacggggagc tctttgtata actatagatg catatggaag aattataaat
     2341 gtaataaata ctcacttggg acttgatagg caggagagag caaaacaatt agacgaaata
     2401 atagactata ggaacagatt agtggggata gttattttat gtggtgattt taatgagaaa
     2461 aatgtctttt taagtatgtt taatgatatg gctatttcac taaacaagtc ttacttacca
     2521 acatttgaaa aatcaaactc tagaatagat tacatttttg ttaataaaaa tactgaacta
     2581 aaaggataca cagtagaaaa aatttacctg tcagaccatt atcctgtaat aggttacatt
     2641 taaatttcaa tataaatgaa attagttgtt ataaaataaa caattttttg ttaagaaata
     2701 gtaaaagaaa tataataaaa aatatcaaaa ataaaactaa ttataagaca taaatttaca
     2761 ataaagttac atttgattaa attccttgtt taacaaaagc tattcaaata taatctaagg
     2821 tagttttgaa atgggaactc tattatgcaa atttaagcta gtgttaaaat gaggtgaagt
     2881 tatgggcaga agaacaacaa gagtttcaag attaggtaaa gaaaaaaaac gaagtgtttt
     2941 aattgtattg gcagctttag ttctaataat gggtggattt acttattttt ttaacagtaa
     3001 atttctgtac aatgggaaaa tcgctaaaaa tgtatatata gaaggagtaa atgtatctga
     3061 tatgactaaa gcagaggcat taaaagctat aacagataag tatactccag aagatttaaa
     3121 tcttgcttat gatgggaaaa aatatacaat atcaccaaaa gatattgatt taaaatatga
     3181 tacagaagat gttgtaaaag atgcttatga aagtacaaaa aaagggtcct attttcaaaa
     3241 cttaaaaaaa tatattgata taagagtgaa taaggcaaat atgaagataa aagctgaata
     3301 tgatgaggca aaacttagtt ccaaagtgtc ttctatagca gatagtataa atgttaagat
     3361 gaaaaatgct tctattagtg ttggaagtgg tggactaagt tatacagact ctgttgtagg
     3421 tagagaattt gatttggcag caaataaaga gtctatatat aatatgataa aaaataaaga
     3481 gcataaaact ttagaactta aagtaaatct tcaaaaacca gatataacaa ctgaacaagt
     3541 aaaaactgta aattctgtta taggtcaata ttcaactact tattcacaag ctgtagaggg
     3601 taggtcatat aatgtaggat tatcagcaag aaaaactagt gatgtattat taatgccagg
     3661 tgaagaattt tcatacaata aacttacagg acctagtaat aaagcaaatg gttacaaaga
     3721 tgcacctgtt atagtttatg gtaagctaga acaatcagca ggaggaggtg tttgtcaaac
     3781 atcttcaaca gtttataatg cggctcttct ttcgggtatg gagataactc aagttacaaa
     3841 tcattcatct gcatctactt atgtgcctaa agggagagat gctactgtga gcgatggagg
     3901 attaaactta aagtttaaaa atccatataa gcatcctgta tatattaaaa attatgcagg
     3961 tggaggaagt gtatcatcag taatctatgg taattctggt gacaaaccaa atatatctat
     4021 agaggtaaaa caaactggtc agaataaata ttctacatat cgaatattta aagattcaag
     4081 tggaaaggtc ataaaaaaag aacatatatc aaatagttct tataaagaat taaaaaaata
     4141 gataattttt tagagaaata tttgtaatat aaaagggagt gtctcaaaat gaacttttta
     4201 gtttatgagg cactcttttt ctgtgaaatc aaatatattt tcatcatttc aacaatacaa
     4261 aagaagcgta tctctatttt gagacagcct tttttgtaaa aattaacact attagttctt
     4321 gttttaatat tacaatcatt aatatataga aaatattcct atatattggt ataattgtaa
     4381 atagatttag ttatataaaa tgtatgagga ggtgacatgg ttgaatttta taggcaatag
     4441 atatgaggta gtaaattctg acgacgtttt agaaattaac aaaatctata aagctagaga
     4501 tgttttttac aggaaaaatg tgttaataaa agttataaag cacaataatt atatctgtga
     4561 agattttgtt tcaaatttaa ttgatgaaag tactgcttta gatgagataa actctcctta
     4621 tatactaaaa ataatagatg ttgggattca ctgtacagaa gaaacaacat tatattatgt
     4681 tgtaagtgaa gactttaatg gtatcggact agatgaatta attctaggta attatcttca
     4741 tttagaagca attgtaaaca taatgataca agttttaaaa gctttagaaa tgatacatag
     4801 gaatcattca tatcatggta gtttaaaatc gagtagtata atagtagata cagaatacaa
     4861 tataaaaatt tgtgattttg gaattacaaa agcaaataat ggggttaata caagaagcta
     4921 tggaaacagg agatatttat gcccacatca actatgtata aattatactg ataaagaaag
     4981 tgattttttt gcaacaggtc ttattctatt tgaatctata tttaaaaaat tgccttttgg
     5041 agaatcaaat tcagaagaaa aaatgctaca atctattgat aagggattag attggaatag
     5101 tataaaagca attaatggaa atactgaact tataaatgtt ataaaaaggc ttcttggaag
     5161 aaataataag tataccagag ccaatgatat tattattgat ttaagtaaag taatgtatga
     5221 aaaagcatat atagaagttg aagatgagaa agaagaagag cagaaacaag acaaagttat
     5281 acaagttaaa aaagaatata aaagtaaaat gagaaaaaaa ttacataaaa aacttgttgt
     5341 tgccggtcta gctatagtca tgatttcaat gattattatt agttccataa tataaaaatt
     5401 gtatattaag tattttaaaa tcaatgtcta taaaggatat acatagaaat tttagtgtag
     5461 tcttaaatta tgaaaggaag tggttattat gttaacaaaa aataatgagg tattaaacgt
     5521 ctaggagtat tttaacaaat agccacctgc ttttacagtt tagaataaaa aagctgtggc
     5581 taaaggtcac agctttttgc tactttttaa aggcaggaga atattaaaaa ggagcaaatt
     5641 atgagcaata taaaaataat agcaagtaat aaatgttgga ttgaagatat agcaaggaaa
     5701 caacttgaag atatttcaaa gttaaatgga attttaagag tagtaggatt acctgactta
     5761 catgcaggta aaatacctgt aggtttagca gttgagacta aaaatattat ttatccacat
     5821 ataattggaa atgatatagg atgcggaatg actttattta aaactggagt tctaaaaaag
     5881 aaatttaaaa aagacaaatg gattaagtca cttagtaaga ttaaagattt gtctgatata
     5941 gaaataaaaa acacatataa agaagaatgt ccaattttaa atttaggaac tatagggagt
     6001 ggaaatcatt ttgtagaaat tcaatgtata agtgaaattt ataataaaga acaatttgaa
     6061 caattaaaat tttcatctga tgatattatg atgttagttc actgtgggtc aagaaattat
     6121 ggagaagata ttttaaaaaa attttatgat aaagatggac ttgaagttga aagtgagaaa
     6181 gctatagatt atattaaaaa acatgataat gctttaatgt gggcagagcg taatcgtgaa
     6241 gctatcagta aaaaaattat gcagtcaata ggtacatctg gagatgttga aacaatattc
     6301 tctataaatc ataactttgt agagaaaagg gaagataaat ttatacatag aaaaggtgct
     6361 gtttcaagtg aaagaggagc tgtgattata ccaggttcaa gaggcagtct atcatatata
     6421 gttatgccta ctgaaaatac agagatatct ttatattctc tatcacatgg agcaggtagg
     6481 aaatggtctc gttcagtttg taaatctcgc cttaaaagta agtatagtaa agatactata
     6541 aaacaaacta aatttaaaag tcagattata tgtaatgatg taaatttatt atttcaagaa
     6601 gctccagagg catataagaa tatagagcag attattgaaa gtttgataga atatgaactt
     6661 attcaagtag tggcaactat gaagccattg attacttata aaggataatt tttaaagtta
     6721 aaaaagatta aaattatatt ataaatagct aattttatgg aacatttaaa agtgttttat
     6781 tattagctat ttttttattt tgtagagacg ataatttata gagctaaatt ctttgatata
     6841 taatgattac aaagttagac tgtattggaa actgcacata catgaattga tgacaatata
     6901 agtgattcca aaatataaat gaaagtataa gcttattttc actataaaaa ttttcactgt
     6961 acaaaaacat taatgacatt atttttattg acataaatat ataatttatg gaataatatt
     7021 agaagcactg atataagtgt ttaaataagg atagaaaagg agaagtgttt tatgaaaaaa
     7081 aatactaaca ttaatgagtc cggagttaaa cttcttaata aataaggagt ttgatatata
     7141 ataactcctt atttattaag ttgttcgcaa aataactatt atcaaagtaa atgatagggt
     7201 gatttaaaag acgataactt ataaataaag gagaaaaaat aatgaatagt aatacatttg
     7261 aaagattaca actaaatgaa gttaaagaat taataaaaat acattgtgta agttcactag
     7321 gaaaaaattt aatagataaa ttaactccta gtgggaatat tggagtagta agaaggaaat
     7381 tagcagaaaa taaagaagct agaaagataa ttgaaaatag taatcacata ccacttgaag
     7441 gattgtttaa tgcaggttct acaatagata aaattgaaaa aggaatgata atagaacctg
     7501 ttgaacttgt aaatattgaa gattttttaa gaggttgtag gaagatgaaa gcttttatgt
     7561 tagaaaaaga attttattca cctacattaa gttcttatgc cttaaatata acagaatgta
     7621 aaagtataga agatgagata aattactgta taaaatctaa taaagttgat tctaatgcta
     7681 gtaaagaatt aaaaaagata agacgaaata tagaaattac agaaggaaag ataaaagata
     7741 gattaaataa atttataaca tcaactgtaa ataaaaagta tatacaagag tttataataa
     7801 gtaaaagaaa tgatagatat gtaataccaa ttaaatcttc ttataaaaat gaagttaatg
     7861 gtactatatt agatacatca tcaaaaggaa atactgtatt tattgaacct attagtgttt
     7921 caaatttaag tacagagtta actatgctaa aagctgatga aactattgaa gaatacaaaa
     7981 tattatctta tttaacagaa cttatatttg agaagataag tcagataaaa ttaaatatag
     8041 agatactttc agaatacgat atgttatttg caaaagctaa gtatagtcaa aaaataaaag
     8101 gaattactcc aaaaataaat aataatggct atataaaaat aattaaaggt aaacatccac
     8161 ttctaacagg agatgcagta cctttagatt ttgaaatagg caaaaattat agaagtctta
     8221 taataacagg tcctaatgca ggaggaaaaa ctgtaaccct taagactgtt ggtttactaa
     8281 ctttaatggt tcaatgtgga tttgatattt ctgcaaaaga aggtagtgaa tttagtgtat
     8341 ttgaaaaagt ttttgtagat ataggggata atcaaagtat tgaaaatgcc ttaagtactt
     8401 tttcatcaca tataaaaaat attgcagaga ttatgagttt atcaaataat tctactcttg
     8461 ttctgtttga tgaaatagga agtggaactg aacctaatga aggagctggt ttagcaatat
     8521 cattattaga agagttttac aaaatgggat gtataactat agcatcaact cattatggag
     8581 agataaaaaa gtttgctaca ttgcatccag aatttgaaaa tgctggtatg atgtttgata
     8641 aagaaacgtt agaaccattg tataagttaa ctattggaaa atctgaagat agtaatgctc
     8701 tttttatttc taaaaaaatg ggaataaaaa atagagtttt agatagagct aaagaatatg
     8761 taattgatag aaactacaat ttagatttag ttaaaagaag taagctacaa tctaatattg
     8821 aagataaaaa tagttctgaa gtcattttaa actatacaga ttataatgta ggggataagg
     8881 taaaattact agatgaagat gattttggaa ttgtatataa gcctatggac aagtttaata
     8941 atgtagaagt attgtttaat gataattttg tttcagtaaa tataaaaaga ttacaactta
     9001 gcataaaagc atcagaattg tatccagaag ggtatgattt agatgtatta tttactagtt
     9061 ttaaagaaag aaaattagaa aaagatattc aaagaggttc aaaaaaagct cttaaaaaga
     9121 ttcagaaaga aattagagag aatagaaaat aaatataaaa agcacaaaag aaagcaatct
     9181 aaagagaaaa gtttatcttt agattgcttt cttattaaca tatcttcata aatccaatga
     9241 ctaacaagat taaaccactt aaccaagata agtttaaatt tacgttttta acaaacatat
     9301 ttcctagtaa acaaccaagt aatactgcaa ttatatttga tattaaagaa aatagaataa
     9361 cttgtatata attcacacct acaaggccac taccaaaacc gatagctaat ccatctaaac
     9421 ttaaagcaag tgcaagtgta aatgcttcag cagatttaag cactttagat ttacttgtat
     9481 ctaagacatc aggttcgata cttacattaa aatttaattt aaggtctaac atattaaaat
     9541 tataattctt tgagtgtata gattttttct taaaataaga tttaaaaaaa ctttcaatta
     9601 gtctagcact tcctaataaa aataaaataa agaaacatat taacattgtt atattttgag
     9661 gtaaaaaatc tctaactatt gtacctgcaa aaagcgatat tgctaaaata gctgaacaaa
     9721 ctacgctgat aattatattt gaatataagg gaactttaac tttatttaca ccatatccaa
     9781 agcttgtcac aaaggcatct atacaaagag aagtaactaa taaaattgat tcaatcacag
     9841 tagattaaca tcctttctct taaattttgt acttatatta gttatagtat tgtaaaaatg
     9901 gataaattgt tacagataat ccaataaatt gttgataaaa ttccaacatc atacaacacc
     9961 taaataacaa aagaatcata tcatataata atataaaacc aatcataata aagcgggtga
    10021 aaataatgga acaaaataat aaggttggga atttcggtga tttgttgaag attttattag
    10081 atgaaaaaga attatcaatg ggagaactaa gtaaaaaaag tggaattgat aaatctacta
    10141 tatctcgtat agctaataat aaacaaaagc caaatataaa tcatttagaa aagatggcaa
    10201 tacatttaaa tattaaccta gaagaactgt tgaaagcttc aggatatgaa tttagaaaca
    10261 gcaataatca aatatttaat gcagatagtg attttagtaa ctttgatgat attcttggat
    10321 ttgcaaattt aatcaatgat aagaacttta atggaaatat tgaaaaagag ttaagtaagt
    10381 gtaagttata tgtccaaaca gatgaaggta aaaaattact ttttgataat tttaataaaa
    10441 aaatagattc tattgaaaaa caaggtcaat ttacagatag attaagacaa atgtatgctg
    10501 atttttgtac agatggactt acaataaaga aatatttatt gattggaagt atgctacttt
    10561 actttgttat atcaacagat gtgattccag acttcgtgtt cccaatagga tttatggatg
    10621 atttagtagc attaaatata gttacaaaat tacttaaaaa tgataagtaa gttttag
//
LOCUS       DAMKNB010000105        10636 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.111, whole genome shotgun sequence.
ACCESSION   DAMKNB010000105 DAMKNB010000000
VERSION     DAMKNB010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 10636)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10636)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10636
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.111"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            569..1999
                     /locus_tag="PC494_003190"
     CDS             569..1999
                     /locus_tag="PC494_003190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDF3913665.1"
                     /translation="MSSQESKPKGNLISNFRDDMRDPKKRAIYTYSSSINLAYNFIGY
                     FVSTVTNIFLTDVAKLGVIMAGGMQIIQSFIKIAVAPITGTVFDKQPFKKGKYYPWLR
                     YAPAALALTYGIFFIVPLMKISPALLLPLMTALLLIASCAQQVVFTIIYAIYPVVAKT
                     PRDRVIGSTTTNIFKEVGKFLVGFSYPLLLVLFADVLGGEGMGYLGTYLFFAAGCLLV
                     FWFSSTEIIKSGAEEEVLQKEEKPKIKASEMAKALFTNVPLMMAFCLEFLICIRSIGL
                     GPLAPYYFKYVIEDERGLAVFLSIMPLVSVAFMFFAPVFIKICREQKLASIISFSICA
                     LCHLLVAWTPWGKTTLGVTMLLAIGGGFSNVVSIINLNFFAGSCDYGHWKSGKDLPGL
                     SMSLYPVAIQVGVLLATTIRTVLMNSMGYQADMVVTEAVKSGFINMISYSMAIPLIIA
                     VVIAILYPVSDKKLNQIREELNQRNA"
     gene            2102..3205
                     /locus_tag="PC494_003191"
     CDS             2102..3205
                     /locus_tag="PC494_003191"
                     /EC_number="2.6.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphate transaminase"
                     /protein_id="HDF3913666.1"
                     /translation="MIEKLLRNTVKELHQYVPGEPIEKVKEKYGVKEIIKLASNENPL
                     GPSPKAIEAMIEMLKQGQLYPEPEANELRRKLAEKLDLKPENFIVANGADNVITLIGE
                     AFINRGDEVIYCNPTFPSYRTATIKNEGIPVEVPLTEDYKYDLQGILDKITDKTKLIC
                     VCNPNNPTGTIVDDKELEEFLKKVPENIITILDEAYIEFLTVPNYVDGLKYVRENYNV
                     IVTRTFSKIYGLAGLRVGYGIAKDEIIRTLFTVKEPFSANRVAISGATAALDDEEFIK
                     ETYELNRVGMAYFKEEFTKMGFDVVDSQSNFLYVDMKTDIPKLFEDLKKRGFVIRPSA
                     THARVSIGTMEENRKFVAVLKEILNIKGEPSIG"
     gene            3220..3456
                     /locus_tag="PC494_003192"
     CDS             3220..3456
                     /locus_tag="PC494_003192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HDF3913667.1"
                     /translation="MKRGVDMNLKINAERCKSCEYCVISCKKGALKISSKINKEGYAH
                     VEVDESKCILCGICYQVCPDNVFEIIKEEACQEA"
     gene            3473..4522
                     /gene="vorB"
                     /locus_tag="PC494_003193"
     CDS             3473..4522
                     /gene="vorB"
                     /locus_tag="PC494_003193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-methyl-2-oxobutanoate dehydrogenase subunit
                     VorB"
                     /protein_id="HDF3913668.1"
                     /translation="MKKMWKGNHAIAEAALRGGCEFYAGYPITPQTEVMEFLSHRMSE
                     LGRTFIQSENEMAAIYMVYGAYASGMRSMTSSSGPGISLKQEGISYLCANHYPCVIVN
                     VQRWGPGLGSLDSAQTDYLRDTRGGGNGDYHLIVYAPNSIQETVDLMYNSFDVAEKYR
                     VPVEILTEAALGQMMEPVEFPEFKKREGDLGWTYDGSNRDHAKVADNQKPTFCMEKRM
                     RITENEQQWEDYQVEDAEYVFVAFGIPSRTTMNAVRRLREQGEKVGIIRPITVWPFPY
                     KAFEKVSKDVKGFISVESTDTGQLVEDVALASKKVCKENVPVYGLFSGNHIPKTLQVM
                     DTYSKIKSGEIKEVF"
     gene            4524..5264
                     /locus_tag="PC494_003194"
     CDS             4524..5264
                     /locus_tag="PC494_003194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoglutarate oxidoreductase"
                     /protein_id="HDF3913669.1"
                     /translation="MATEKLTPSVVSIPNKFCPGCGHGIVNRIIAEVIEEHGYEKNHV
                     LTLGVGCVCNMNFSWNGDKMQTAHGRASSTAIGVKVALPDTLVMTYQGDGDAYVIGLS
                     ETLNTAYRNHNVTVFVINNNNFAMTGGQMSWTTMPGQVTTTSVNGRDIKTTGSPLKVP
                     EMVANFFDVAYVARGSVHSPKEIINLKKYIKNAIEAQLNGEGYSLVEILAPCPTNWGV
                     SLEKSIKWMEEEIVPYYALGEFKQRDGE"
     gene            5267..5806
                     /locus_tag="PC494_003195"
     CDS             5267..5806
                     /locus_tag="PC494_003195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoacid:acceptor oxidoreductase family
                     protein"
                     /protein_id="HDF3913670.1"
                     /translation="MEKELVFAGFGGQGVLTLGLIVAESALELGKQVTWMPAYGPTMR
                     GGKAYSVVKFSDESIGGPDMEEIDVLVAMNKPSLDYINLVKEGGTVVINTSAIDENVT
                     LREDISVVKINCQELAQKVNNPKAANIVVLGALIAKTGLFEKELALKTMCDFFEEKGK
                     GKFNVQNEAAFMEGYNNAI"
     gene            5930..8029
                     /locus_tag="PC494_003196"
     CDS             5930..8029
                     /locus_tag="PC494_003196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate--CoA ligase family protein"
                     /protein_id="HDF3913671.1"
                     /translation="MSLEKLIRPKSIAIVGVTDKLGFGRSAALSIVKSKETDRVYYVN
                     PKREELFGRKCYKTIQEVPEVVDCVVVCTPRNVVPSVLKDSGELGTKAAVVYASGFAE
                     EGTEEGTDLENQLIEISNTYDMKILGPNCMGLLNCIDKVNLWAGGSKWDLYTKKPGIG
                     IVGQSGFITAEIVSSDYFNISYGFSTGNGNIVTLEDAVDFLVDDDYASVIAIYLEGLK
                     NPQKFIDALKRAAQKRKPVIILKSGRSEKGAISAASHTGNLAGSSKAFESIFEKYGVI
                     SVENLEQFMCLAQAFSVLDGNLPANSNFAAINFSGGENTICADLAEENGVELAEISSE
                     TKEEMKKYLPGFATPKNPLDATTALFHEKDMIVGLLHTFEKDDSVGFTMVGANIRDEE
                     NEMHETLCKAVSEAREQGLKKPVFAVPTLEGNRYLDYRTRLEDNQVPIMSSVGTTFTC
                     FNKMAKFIDYDYSKRTLEFKAVKKRESNNVVALSELDSKIEMKKYGVPVPGQGNAKSI
                     DELDEILKYIKYPVVLKINSSEILHKSDVGGVKIGIKNRDEAVDAYNEILTNVKKAKP
                     DANIDGILVQEMVESGIEIIIGITNDDQFGPLLLVGLGGVFVEVFKDTTLYPLPINHD
                     EAIMMLKKLKSFKLLNGYRGSEPCDIDALADMMVKLGKYAYENKDEVKEIDLNPVFVY
                     PKGKGVCAVDALIVKYK"
     gene            complement(8296..8811)
                     /locus_tag="PC494_003197"
     CDS             complement(8296..8811)
                     /locus_tag="PC494_003197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferritin"
                     /protein_id="HDF3913672.1"
                     /translation="MISAKMEKLLNEQINHELYSAYLYLSMSSYLEAEGLKGFSNWFY
                     VQYKEETDHAMFFYKYLHNVGGKVQLDAIPMPDSDFTSAMDILERTLAHEKKVTALIN
                     NLAAVANSESDFRTSQFLLWFISEQAEEETNCEDNIKRVKLAGEGGLFFVDQEFANRT
                     YAAPTNPPVTI"
     gene            complement(8903..10114)
                     /locus_tag="PC494_003198"
     CDS             complement(8903..10114)
                     /locus_tag="PC494_003198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HDF3913673.1"
                     /translation="MSNKQGSNIKDVKIKNKLIILKLLSTNTPMSRVDLAKSTGLTKM
                     TLSNLVTELINENMIREIESSTLNAHSSGRKPILLDISNISPCICGILIRRNICKVII
                     SDLKGNIVKQLSETYPKCLSNDVLKDIIKRMFTKIMKINKRDIIGIGISSIGPVDDIN
                     GTILNPPDFGNISNLNIVDFIKEMSDLPIFLINDANSGALAEKMYGLGKNISNYIYLH
                     IMNGIGAGLVLENKLHTGNLGQSGEIGHTSINFSGPLCSCGNNGCLDYYTSVSNLIKR
                     IESLSHIYPNSPLINCKDFSLVKLIDEANNKDSLAMFLLDEFCTYVSYALVNTLTLID
                     CSSIIIGYDFNIPGTFIENTLLKKLTASASFSKYKKISVRHSNFGANAPLIGSIAIVS
                     YNFFNGSINFY"
BASE COUNT         4047 a         1275 c         1910 g         3404 t
ORIGIN      
        1 attggtttta gattaatata gctataataa tttatgatat tagatggaaa ttacgtaaaa
       61 atagaaaatt gaaaattctg aaatttttgc atattgatat ttatctcata gattcttttt
      121 tgtaattgta acacgctttt atttttaaat caatagtaca tgtataaaaa taaaaggaat
      181 ttaaataaga aaaagatatt tttaatatct ggatgtagta tagaaatatc ttgaataaat
      241 tattcttgaa taaaattata aaaaattaaa atcactagaa atatgataaa ataatttaaa
      301 atacgcattt caatgacatt tcaaaacaag aaaataataa aaaacaaacc taaattaagt
      361 ctaaatagct ttttagttaa ttttagtagt aaaaaataaa acttaaaaag tatttgacaa
      421 ttatgaattt tgagaatata attaaattaa aattatacac atataaaaat atattcctga
      481 atcaagaatg agatatttaa gattcaaaat atatattatt atacgtgaat aataaaaagt
      541 aagaaaattt tataagggag gggtagatgt gagtagtcaa gaaagcaaac caaaaggaaa
      601 tcttatatca aattttagag atgatatgag agaccctaag aaaagagcaa tatacacata
      661 ttcaagttct ataaacttag cgtacaattt tataggttac tttgtatcaa ctgttacaaa
      721 tattttttta actgatgtgg caaaacttgg tgtaattatg gcaggtggta tgcaaattat
      781 acaatctttc ataaaaattg ctgtagctcc tataacaggt acagtatttg acaaacaacc
      841 attcaaaaaa ggaaagtatt atccatggct tagatatgca ccagcagcgt tagcattaac
      901 atatggaata tttttcatag ttccattaat gaaaataagt ccagcattac ttttaccttt
      961 gatgacagct ttattattaa tagcatcttg tgctcagcaa gtagttttca ctataattta
     1021 tgctatttac cctgtagttg ctaagacacc tagagaccga gttataggct caactactac
     1081 gaatatattt aaagaagttg gtaaattctt agtaggtttt tcatatccgt tattattagt
     1141 tttatttgca gatgtattag gtggagaagg aatgggttat ttaggtacct acttattctt
     1201 tgcagcagga tgccttttag tattttggtt ttcttcaaca gagataataa aatctggagc
     1261 agaagaagaa gttcttcaaa aagaagagaa gccaaagatt aaagcaagtg aaatggcaaa
     1321 agctttattc actaatgtac cacttatgat ggcattttgt ttagaatttc ttatatgtat
     1381 aagatctata ggattaggac ctttggctcc atattatttt aaatatgtaa tagaagatga
     1441 acgtggatta gcagtatttt tatcaatcat gcctttggta agtgtagcat tcatgttttt
     1501 cgcaccagtg tttataaaaa tctgtagaga gcaaaaacta gcttcaataa tttctttttc
     1561 tatatgtgca ctatgccact tattggttgc atggactcct tgggggaaaa ctactttagg
     1621 agtaactatg ttgctggcaa ttggtggagg tttttcaaat gtagtatcaa taataaatct
     1681 taatttcttt gccggttctt gtgattatgg gcattggaaa tcaggaaaag atttgcctgg
     1741 tttaagtatg tcactatatc cagttgcaat acaagtagga gtattacttg caactactat
     1801 aagaacagtt ttaatgaact caatgggata tcaagctgat atggtagtca cagaagcagt
     1861 taaatcaggt tttataaata tgatttctta ttctatggca atacctttaa taatagctgt
     1921 tgttatagca atactatatc cagtaagtga caagaaatta aaccaaataa gagaagagtt
     1981 aaatcaaaga aatgcttagt taaaagaaag ttaagtagat ggttaattta agctattaaa
     2041 gtaagtagac gcaatagcgt ttatataaat gaaaatacat atacagaggg ggcttttaaa
     2101 aatgatagaa aaattattga gaaataccgt aaaagaatta catcaatatg ttccaggtga
     2161 accaatagaa aaagttaagg aaaaatatgg tgtaaaagaa ataataaaat tagcttcaaa
     2221 tgaaaatcct ctaggaccat caccaaaagc aatagaagct atgattgaaa tgctaaaaca
     2281 aggtcaactt tatccagagc cagaagctaa cgaacttaga agaaaattag ctgaaaagct
     2341 agatttaaaa ccagaaaatt ttattgttgc taatggtgcg gataacgtta tcactctaat
     2401 aggtgaggct tttataaata gaggagatga agttatatat tgtaacccaa catttccatc
     2461 atatagaact gcaactataa aaaatgaagg gataccagta gaagtacctt taacagaaga
     2521 ttataagtat gatttacaag gtatattaga taagattaca gataaaacaa aattaatatg
     2581 tgtatgtaac cctaataatc caacaggaac aattgtggat gataaagagt tagaagaatt
     2641 tttaaagaaa gtccctgaaa atattataac tatattggat gaagcatata tagaattttt
     2701 aacagttcct aattatgtgg atggacttaa gtatgtaagg gaaaattata acgttatagt
     2761 aacaagaact ttctctaaaa tatatggtct tgcagggctt agagtaggat atggtattgc
     2821 taaagatgag ataataagaa ctttatttac agtaaaagag cctttctctg caaatcgtgt
     2881 tgctataagt ggagcaacag cagcacttga tgatgaagag tttataaaag aaacatatga
     2941 attaaataga gttggaatgg cttactttaa agaagagttt acaaaaatgg gatttgatgt
     3001 tgtagattca caatcaaatt tcctttatgt agatatgaaa acagatatac ctaagttatt
     3061 tgaagacttg aaaaaaagag ggtttgtaat aagaccaagt gctacacatg cacgtgtaag
     3121 tattggaact atggaagaaa ataggaaatt tgtagcagtt ttaaaggaaa tattaaatat
     3181 taaaggagag ccaagtattg gataatagat agaaatatta tgaaacgggg tgtagatatg
     3241 aacttaaaaa taaacgcaga gagatgtaaa agttgtgaat actgcgttat atcttgtaaa
     3301 aaaggagcat taaaaatatc aagtaagata aataaagaag gttatgctca tgtagaagtt
     3361 gatgagagta aatgcatact ttgtggaatt tgctatcagg tgtgtccaga taatgttttt
     3421 gaaataatta aagaagaagc atgtcaagag gcttagaagg agttgggata atatgaaaaa
     3481 gatgtggaag gggaaccacg ccattgcaga agcagcccta agaggaggtt gtgaatttta
     3541 tgcaggatat ccaattacac cacaaacaga ggtaatggaa tttttatcac atagaatgtc
     3601 tgaacttgga agaactttta tacagtccga aaatgagatg gctgctatat atatggtata
     3661 tggagcatat gcaagtggaa tgaggtctat gacgagttct tcaggaccag gaatatcttt
     3721 aaaacaagaa gggatttctt acttatgtgc aaatcattac ccttgtgtaa tcgtaaatgt
     3781 acagagatgg gggcctggtc ttggctcatt ggactcagca cagacagact atctaagaga
     3841 tactagaggg ggaggaaatg gagattatca tttgatagtt tatgcaccaa acagtattca
     3901 agagactgta gatttgatgt ataactcatt tgatgtagcg gagaagtaca gagtgcctgt
     3961 cgaaattttg acagaagcag ctttaggtca aatgatggaa ccagtagaat ttccagagtt
     4021 taagaagaga gaaggagatt taggttggac ttatgatgga agtaatagag accatgcaaa
     4081 ggttgcagat aaccaaaagc caactttttg tatggagaaa cgtatgagaa taactgaaaa
     4141 tgaacaacaa tgggaagatt atcaagtaga agatgcagaa tatgtgtttg tagcgtttgg
     4201 tataccatca agaacaacta tgaatgctgt tagaagactt agagaacaag gtgaaaaagt
     4261 tggaataata agaccaataa cagtatggcc tttcccatat aaagcatttg aaaaggtaag
     4321 taaagatgta aaaggattta tctcagtaga atcaacagac acaggtcaat tagtagaaga
     4381 tgttgcttta gcctcaaaga aagtatgtaa agaaaatgta cctgtgtatg gtttatttag
     4441 tggaaatcat ataccaaaaa cattgcaagt aatggacact tatagcaaaa taaaatctgg
     4501 cgaaatcaag gaggtgttct aatatggcta cagaaaaatt aacacctagc gttgtttcaa
     4561 taccaaacaa gttttgccca ggttgtggtc atggaatagt aaatcgtata atagcagagg
     4621 taatagaaga acatggatat gaaaaaaatc atgtattaac attaggagtt ggttgtgtct
     4681 gcaatatgaa ttttagctgg aatggtgata agatgcaaac tgcacatggt agagcttcat
     4741 ctacagctat aggagttaaa gtagcacttc cagatacatt agtaatgact taccaaggtg
     4801 atggagatgc ttatgttata ggtctttctg aaactttaaa tacagcatat agaaatcata
     4861 atgtgactgt atttgtaata aacaataata attttgcaat gactggtgga caaatgtcat
     4921 ggaccactat gccgggtcaa gtcacaacaa caagtgtaaa tggaagagat ataaagacta
     4981 ctggtagtcc actgaaagtt cctgagatgg tggcaaactt ctttgatgta gcatatgtag
     5041 caagaggttc agttcatagc ccaaaggaaa taattaatct aaaaaaatat ataaaaaatg
     5101 caatagaagc tcaattaaat ggagagggat attccttagt tgaaatatta gcaccttgcc
     5161 caactaactg gggtgtatca ctagagaaat ctatcaaatg gatggaagaa gaaatagtgc
     5221 catattatgc tcttggcgaa tttaagcaaa gggatggtga atagttatgg aaaaagagct
     5281 agtatttgca gggtttggtg gtcaaggagt tttaactctt ggtctgattg tagctgagtc
     5341 agcacttgaa ttggggaaac aagtaacttg gatgcctgca tatggtccaa ctatgagagg
     5401 tggaaaagcc tatagtgtag taaagttttc tgatgagagt ataggtgggc ctgatatgga
     5461 agaaatagat gttttagtag caatgaataa accatcttta gattatataa atttagttaa
     5521 agaaggtgga acagtagtta ttaatacatc tgcaatagat gagaatgtaa cattaagaga
     5581 agatataagt gtagttaaaa taaattgtca ggaattagct caaaaagtaa acaatccaaa
     5641 agcagcaaat atagtagtac ttggagcatt aattgctaaa actgggttat ttgaaaaaga
     5701 attagcttta aaaactatgt gtgatttctt tgaggaaaaa ggaaaaggaa agtttaatgt
     5761 tcaaaatgaa gcagcattca tggaaggcta taataacgcc atttgataaa ttacccttat
     5821 cttaagtgat ttatctcaag atttaataat ctttagtgcc aagagaaact tcatcttgag
     5881 ataaaattca cttaaaatca caactataaa catataggag cgtgaattta tgagtttgga
     5941 aaaacttatt agaccaaaaa gtattgctat agtaggagtg actgataaac ttggttttgg
     6001 aagaagtgca gcacttagta tagtaaaaag taaggaaaca gatagagtat attatgttaa
     6061 tcccaaaaga gaagaattgt ttgggagaaa atgttataag acgatacaag aagttccaga
     6121 agtagtagac tgtgtagtag tatgtacgcc tagaaatgta gttccatctg tattaaaaga
     6181 ttctggagag ttaggaacaa aggcagcagt ggtatatgct agtggatttg cagaggaagg
     6241 tacagaggaa ggtacagatt tagaaaatca acttatagaa atatcaaata catacgatat
     6301 gaaaatattg ggtccaaact gcatggggtt gctaaattgt atagataagg ttaatctatg
     6361 ggcaggaggt tctaaatggg atttatatac taaaaaacct ggtataggaa ttgtaggtca
     6421 aagtggattt ataactgctg aaattgtttc aagtgattat tttaatatat cttatggttt
     6481 ttcaacagga aatggaaata tagttacact agaagatgca gtagatttcc ttgtagatga
     6541 tgattatgca tcagtaatag caatttacct tgaaggttta aaaaatcctc aaaaatttat
     6601 agatgcttta aaaagggcag cacaaaaaag aaagccagta ataatattga aatcaggaag
     6661 gtcagaaaaa ggtgctattt ctgctgcttc tcatacagga aatttagctg gttcgagtaa
     6721 agcttttgaa agtatttttg aaaaatatgg agtaatttct gtggaaaatt tagaacagtt
     6781 tatgtgttta gcacaagctt ttagtgtttt agatggtaat ttacctgcaa attctaattt
     6841 tgcagcaata aacttctcag gaggagaaaa tactatttgt gcagatttag cagaagaaaa
     6901 tggtgtagaa cttgcagaaa tatcttctga aactaaagaa gaaatgaaaa aatatcttcc
     6961 aggatttgca acacctaaaa atccactaga tgctacaaca gcattattcc atgaaaagga
     7021 tatgatagta ggtttattac atacctttga aaaggatgat agtgttggat ttactatggt
     7081 aggtgcaaat ataagagatg aagaaaatga aatgcatgaa accctttgta aagctgtaag
     7141 tgaagctaga gaacaaggat tgaaaaaacc tgtgtttgca gttcctacac ttgaaggaaa
     7201 tagatattta gattatagga ctagattaga agataatcaa gtgcctataa tgtcatcagt
     7261 tggaactaca tttacttgtt ttaataaaat ggctaagttt atagattatg attattcaaa
     7321 aagaacttta gaatttaaag ctgttaagaa aagagagtca aataatgtag tagcattatc
     7381 agaattagat agtaagattg agatgaaaaa atatggagta ccagttccag gacaaggtaa
     7441 tgcaaaaagt attgatgaat tagatgaaat cttaaaatat attaagtatc ctgttgtttt
     7501 aaaaataaat tcttctgaaa tattgcacaa atctgatgtt ggaggagtta aaataggaat
     7561 taagaataga gatgaggcag tagatgcata taatgagatt ttaactaatg taaaaaaagc
     7621 aaaaccagat gctaatattg atggtatatt agttcaagaa atggtagaaa gtggtataga
     7681 aattattatt ggtataacta atgatgacca atttggacca ctgttattag tcggtttagg
     7741 aggagtattt gtagaggtat ttaaagatac tacattatat ccattaccta taaatcatga
     7801 tgaagctatt atgatgctta aaaaactaaa atcatttaag cttttaaatg gctatagagg
     7861 aagtgagcct tgcgatattg atgctcttgc agatatgatg gtcaaattag gaaaatatgc
     7921 ttatgaaaat aaggatgaag tcaaggaaat agacttaaat ccagtgtttg tatatcctaa
     7981 aggaaaaggc gtatgtgcag tagatgcctt aatagttaaa tataaatagt ttataagttt
     8041 tggtattcaa ccataattaa agcaccgact gaaaatcaca ttttgtaagt tagatagtgt
     8101 gattttcagt caccccaaat ttaatttaaa aatattttaa aatgaaagta tagttttaag
     8161 tttcattgtg aaatagcact gtataaacaa taaaatacta cgtataaaac gaataataaa
     8221 aggtgtttta atgataagaa tcaatcttga ttttcattaa aacaccttct ttattatatt
     8281 aaaaattttt aaacgttata ttgtcacagg tgggtttgtt ggagctgcat atgtacgatt
     8341 agcaaattct tggtcaacaa agaatagacc accctctcca gcaagtttaa cacgttttat
     8401 attgtcttca caatttgtct cttcttctgc ttgttcagat ataaaccaaa gtaagaattg
     8461 agaagttcta aagtctgatt cagagtttgc tacagctgct aagttgttta ttaaagctgt
     8521 aacctttttt tcatgagcta acgtacgctc aagaatatcc attgcagaag taaagtctga
     8581 atctggcatt gggatagcat caagctgaac ctttcctcct acattatgta agtatttgta
     8641 aaaaaacata gcgtggtctg tctcttcttt atattgaaca taaaaccaat tagaaaatcc
     8701 tttaagtcct tctgcttcaa ggtaagaaga catagaaaga taaagatacg cagaatataa
     8761 ttcatggtta atctgctcat taagtaattt ttccatttta gctgaaatca tttttatacc
     8821 tccaaatttt aaatgctctt ataaaatata ataatattaa atggaaaaat attcaataaa
     8881 agtgtttaaa tattttacat atttaataaa aatttatact accattaaaa aaattataac
     8941 ttacaatggc tatagagcca attaatggtg catttgctcc aaaatttgaa tgccttacac
     9001 ttattttttt atatttagaa aaacttgctg aagcagtcaa tttttttaat aatgtatttt
     9061 ctataaatgt accaggtata ttaaagtcat agcctattat tatagaacta caatcaatca
     9121 atgtaagtgt attaactaat gcatatgata cgtatgtaca aaattcatca agcaaaaaca
     9181 tggcaagact atctttatta tttgcctcat ctattaactt gactaaagaa aaatctttac
     9241 agttaattaa tggggagtta ggataaatat ggctcaatga ttcaattctt ttaattagat
     9301 tactgacact tgtataataa tctaaacatc cattgttacc acaactgcac aatggtccac
     9361 taaaattaat tgatgtatgt cctatttctc cactttgtcc taggttgcca gtatgaagtt
     9421 tattttctag aactagacca gctccaatac cattcattat gtgtaggtat atataatttg
     9481 atatattttt acctaaacca tacatttttt ctgctaatgc acccgaatta gcatcattta
     9541 tcaaaaatat tggcaaatca gacatttctt ttataaaatc tactatattt aggtttgata
     9601 tatttccaaa atctggggga tttagtatgg taccatttat atcatctact ggacctattg
     9661 aagaaatacc aattccaatt atatctctct tgttgatttt cattatttta gtaaacattc
     9721 tttttattat atcttttaaa acatcatttg atagacattt agggtaagtt tcagaaagtt
     9781 gttttacaat attacctttt aaatctgaaa taattacctt acatatattt cttcttatta
     9841 ggattccaca aatacaaggc gatatattag aaatatctaa taaaatgggt ttacgacctg
     9901 atgaatgtgc atttaaagtt gatgactcta tttccctaat catattttca ttaataagtt
     9961 cagtaactag atttgataaa gtcattttag taagtcctgt agacttagct aaatcaactc
    10021 tggacatagg tgtatttgta gaaagtaatt tcaatattat taacttattt ttaattttta
    10081 catctttgat gttagaacct tgtttgttac tcatcataaa tctccttaaa taaagttaag
    10141 tgttttattt attttcaagt atactatcac cttataatag agtaacattt ttttacttga
    10201 aaatatcatt aattagaata tatcacatta tatatcataa aacatataaa aaaatattag
    10261 aattaaatta aaagtgaaaa gtagattgat atataaatag taaatactta attaaaaaaa
    10321 gataatgata gcaataatta ttgttaccaa gaatctacta cttcaagtgt taccttaggt
    10381 atttaagttg atagtggttt gcacgtaata aacttgatgt aatatatatt cttaataata
    10441 ttgataaaag atttacttaa aaataatata gatcatgtaa acatataatc tatttattgt
    10501 atacaataaa atttcatttt gtaaaacagt gaattaaata tgtaatatag atatcaattt
    10561 ttattacaaa ttgttactaa atataggtac attagaacaa aaatctagta aattgtaact
    10621 aaaatgtaaa tttttc
//
LOCUS       DAMKNB010000106        10321 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.112, whole genome shotgun sequence.
ACCESSION   DAMKNB010000106 DAMKNB010000000
VERSION     DAMKNB010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 10321)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10321)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10321
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.112"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            complement(144..743)
                     /locus_tag="PC494_003199"
     CDS             complement(144..743)
                     /locus_tag="PC494_003199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease H family protein"
                     /protein_id="HDF3913674.1"
                     /translation="MAKQKFYAVKKGKNIGVYNTWDECKKQVNGFSGAEYKSFSTFQE
                     AKEYIDGSEKLSFQEDKEFIEAYVDGSYEHSVKMYGSGVVILKNNEVIKTYSEKGKEK
                     TLVSMRNVAGEIEASKIAMQYCIDNNVQNLILYFDYEGIEKWCTGVWKTNKEGTIAYK
                     NFYDSIKNKLNVKFTKVKAHSGNKYNEEADKLAKKAIGV"
     gene            complement(761..3880)
                     /locus_tag="PC494_003200"
     CDS             complement(761..3880)
                     /locus_tag="PC494_003200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HDF3913675.1"
                     /translation="MDNIISVLNDVVFLDIEVSGLDCLNSEILEVGAVKVKDWKIYTY
                     ESLIKNKFEVPVEVFSVCKNLDKNDLEIANEIELVEDRLVNFVEDSFIICHDLSLKKK
                     FLEYHMPKLKNKFIDLIELAVILEPYHKDYSLEYLKNTLTNCNSKVENRALSDAIDII
                     NIVNCLLVKFNNYEKTTLEPLSFKINSYLKKFNLPTWEWSKFLEEANYDLSNNINIKK
                     EYNIFDSKEEKKKERETLKILNEEEKNYEELLKYKTIWENKEGFTYEYRPGQYELTKT
                     IRELFRNSEDEEKIACIEAPTGIGKSVGYLLPAILEARINKKRLLISTDTKELQIQLI
                     NKDIPNVLDSLGLNGKVSYGYIKGKNNYICIDRLEAYIDDYESQNPTKGEILSLIFLK
                     RLVEGGKYGDIEEINYLVFDNFKEISTHLRNVSCDPNMCRPKKCKKDCLYKNRIEELK
                     EEHITVVNHSLLAKWPYKDEKPLENIIVDEAHNLTEKGYDFFSSIINSKSLRYLLQEI
                     YPYEFIQNSSFIYKKYSRNMRKIKAFDKFYNVLKIGREDKQKIARSINLIIEEIDSIL
                     KFGNCNEYNNVSNYNLRWELNLQIDEIVGKLKKDGIDTEISYRAYSEKIKLSCEKIIK
                     NLVSIIIIIYRNIDDDSIDKEADIYKFGKAKTRDLEDIKIIFEIFLEYDEKDDYARIV
                     EIDKNYNDFEFRVVPLKIADLFEENILSQLEKGIFLSATLSLSESMSYFKNTLGIDRV
                     KNVEKIIEPIFDYKNRVSVVGFSDICEYRNSEFPNEMSKIISNISKITEGHTLALFNS
                     KDRQEKTYEILKKYLHSFNLEIYADKKGIRHLNDLNRKCVVLGSKGCFEGVDIPGDGL
                     VCVTLDKLPNLNPKDPLYFTIMKKYGIDYYTINYPQMTIKVKQAMGRILRSKYDYGCF
                     VIFDVGTNISVLKRLEKDLHDCKISKVNSNEFYTYIRRHLNKYRSLILKSVIFDTIKA
                     LNVDAKMDNNDVDKDIIKKDINENIRQRAVKGEVYHIDIIKKDMKVKYFDRNYLINLD
                     IFMREEDKN"
     gene            4101..4925
                     /gene="pdaA"
                     /locus_tag="PC494_003201"
     CDS             4101..4925
                     /gene="pdaA"
                     /locus_tag="PC494_003201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="delta-lactam-biosynthetic de-N-acetylase"
                     /protein_id="HDF3913676.1"
                     /translation="MKKDSLKKYIMIGAFALILFGIASINFKSLDKTKTQISSPTLDT
                     HEYDWYFNPREDGKQPSPIKEADFFKKYGAYYVGNPNEKVIYLSFDAGYESGNTPKLL
                     DTLKKHNAKAQFFVVESYIKSNPELIKRMEKEGHLVCNHSKSHPSMAGITDFEKFKEE
                     ITSVEKAYKDVTGKEMPKYFRPPMGKFSEQSLKYTQDLGYKSIFWSFAYVDWYEKKQP
                     THEFAKNKIYSRTHPGAIVLLHPNSSTNTEILDEVLTHWEKEGYKLKTLDYLNNKK"
     gene            complement(5022..5807)
                     /locus_tag="PC494_003202"
     CDS             complement(5022..5807)
                     /locus_tag="PC494_003202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDF3913677.1"
                     /translation="MIVKIDNTLEKEFWQYVSHEESLNLFIIGYVENYGFSSQYQDIW
                     SQVEDGNITSIILKNKSTLIIYSFKNNFNIGEMKNHIKDLDVESISGKKCVIDRLISK
                     YKDFYEKLDNKFCVLKEIKEIDFSNMKEYKIENAQEKDIDEIGKLLNRSDYKVSKNYI
                     EERKVHLKEGNVRAYFIRNDDTMISTVSTGMETSFLAMVVSVSTDKRYRGKGLASYMV
                     YNLSKELLLEGKVPCLFYNNDVAGKIYHNIGYKEINEWTILFK"
     gene            6272..6637
                     /locus_tag="PC494_003203"
     CDS             6272..6637
                     /locus_tag="PC494_003203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF3913678.1"
                     /translation="MKIRAEYTCLLEIVHDIIKGKWKTILIFELRQSNKTFSELQHNI
                     YGINQKMLIQQLKELRDFGIIDKISSAGYPLHVEYFLTNRGKKMLKAVEIMQEIGIEY
                     MLEHGQQEILDNKGICYNK"
     gene            6715..7269
                     /locus_tag="PC494_003204"
     CDS             6715..7269
                     /locus_tag="PC494_003204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HDF3913679.1"
                     /translation="MSIALILIDIQNDYFKNGKCELFQSEETAENAKKILLFFRKNNL
                     PVIHIQHISTDKTASFFLPNTHGSEINKIVFPLDNEEIITKHTPDSFFETDLQSILEK
                     KNITNLVICGMMSHMCIDTSVRTAKKLRYDITLISDACTTKNLSWNNIEINANTVHQV
                     FMASLQNSFADVKNTDKFLSNYHK"
     gene            7489..8163
                     /locus_tag="PC494_003205"
     CDS             7489..8163
                     /locus_tag="PC494_003205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HDF3913680.1"
                     /translation="MNHHILIQFEYIARIITAGFCGALIGYERKNRLKEAGIRTHFIV
                     ALASALIIIVSKYGFNDIVGTPGIGLDPARVAAQVVSGIGFLGAGLIFIRNQSVSGLT
                     TAAGIWATAGTGLAIGSGLYLVGIVSSIIIVIVQITLHRDRKWMKLPTAEQVSLKISN
                     STDSIEYIEGKFKKSNIEIINMNIKRLDGDWLEVVIYTKLPKGYKKTNLLKLFSDNPL
                     IETLEI"
     regulatory      8518..8614
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            8668..8844
                     /locus_tag="PC494_003206"
     CDS             8668..8844
                     /locus_tag="PC494_003206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3913681.1"
                     /translation="MFRDEMDKCTHMLTAYISSLYDYCDFIDTQLDDFILEYGENVVE
                     SCLHQVMVLVSKYN"
     gene            complement(9032..9271)
                     /locus_tag="PC494_003207"
     CDS             complement(9032..9271)
                     /locus_tag="PC494_003207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3913682.1"
                     /translation="MKCSNCGSVNIEKGILTTGGIYAETIGLKYRGDGKLDKVINKTF
                     PVQSTIYSDLCLDCGEIVRTYIKDNTDRNWCKDKK"
     gene            complement(9405..10214)
                     /locus_tag="PC494_003208"
     CDS             complement(9405..10214)
                     /locus_tag="PC494_003208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HDF3913683.1"
                     /translation="MKDYYKIGEISKIYGIGRDSLMYYEEIGILRPVRDINGYRMYNI
                     SDIWKLNLIKEFRSLNFPMKKIKEYLDDRSIESTKNILNEELDLIDKKIAEFISHKEN
                     IIKRLSSIESVIQNTKIDEIEVVYIEKRKALELNADIKRDEDFDFLIQKLQKEYEDRF
                     NILGNNNIGSAFSTEAINKGIFNEFKSVFCFLESNEKVYNIVFDEGYYVTLNYTGSNS
                     NNKIYMEKVFKFIEENNYKIIADPIEIYKIDIHETGIVEEFVTEIQVPITK"
BASE COUNT         3573 a         1589 c         1023 g         4136 t
ORIGIN      
        1 ataatacaat ctgctttttt aatcaaaatt tatttaatta taagttgttt aattacaagt
       61 tgtttaatta caagttgttt aattataaag taggaattta gatatactct tataccatgt
      121 aattatgtat aaatattttt ttattataca ccaatagctt ttttagctaa tttatctgct
      181 tcctcattat acttatttcc agaatgagct ttaacctttg taaattttac attaagctta
      241 ttcttaatac tgtcatagaa atttttatat gctatagttc cttctttatt tgttttccaa
      301 actccagtac accacttttc aatcccttca tagtcaaagt ataaaatcaa gttttgaaca
      361 ttattgtcaa tacagtactg cattgcaatt ttagaagcct ctatctctcc agctacattt
      421 ctcatactta ctaaagtttt ctcttttcct ttttcactat aagtttttat aacttcatta
      481 ttttttaaaa tcacaacacc cgaaccatac atttttactg aatgttcata acttccatct
      541 acatatgctt ctataaactc cttatcttct tgaaaactca atttttctga cccatcaata
      601 tattctttag cttcttgaaa agtagaaaaa ctcttatatt cagctcctga gaatccattt
      661 acttgttttt tgcactcatc ccatgtatta tatacaccta tatttttacc ttttttcaca
      721 gcataaaact tttgttttgc caaatatatc actcccactc ttaattttta tcttcttctc
      781 tcataaatat atctaaattt ataagatagt ttctatcaaa atattttact ttcatatctt
      841 tttttataat atcaatatgg tacacttctc cttttacagc tctttgtctt atattttcat
      901 ttatatcttt ttttataata tccttatcaa catcattgtt atccatttta gcatcaacat
      961 tcaacgcttt tatagtatca aatataacag attttagtat taaacttcta tatttattta
     1021 aatgtcgcct tatataagta taaaactcat tgctattaac ctttgaaatt ttacaatcgt
     1081 gtaaatcttt ctctaatctc tttaacacac ttatattagt tcctacatca aaaatcacaa
     1141 aacatccata gtcatatttg cttcttaaaa ttctccccat agcttgcttt acctttatgg
     1201 tcatttgagg ataatttata gtatagtagt ctataccata cttcttcatt atagtaaaat
     1261 acaaagggtc ttttggattt agattcggaa gcttgtctaa agttacacaa accaaaccat
     1321 cccctggaat gtctacgcct tcaaaacatc cttttgagcc aagtactaca cattttctat
     1381 ttaaatcgtt aaggtgtcta atcccctttt tatcagcata aatttctaag ttaaaactat
     1441 gtaagtattt tttcaatatt tcataagttt tttcttgtct atctttacta ttaaaaagag
     1501 ctaatgtatg accttctgta atctttgata tattagatat aattttactc atctcatttg
     1561 gaaattcaga atttctgtac tcacaaatat cagaaaatcc aactacagag actctatttt
     1621 tataatcaaa aattggttct ataatctttt ccacattctt aactctgtct attcctaatg
     1681 tatttttaaa ataagacata ctttcagata aactcaaagt tgctgataaa aatattcctt
     1741 tttctaattg agataaaata ttttcttcaa ataaatctgc tatttttaat ggcactactc
     1801 gaaattcaaa gtcattataa ttcttatcaa tttcaactat ccttgcataa tcatcctttt
     1861 catcatactc taaaaagatt tcaaatataa tctttatatc ctctaaatct cttgtctttg
     1921 cctttccaaa tttatatata tctgcttctt tatctatact atcatcatca atattcctat
     1981 aaattattat tattattgaa actaaatttt ttattatttt ctcacaactc aactttatct
     2041 tttcactata ggctctataa cttatttcag tatctatacc atcctttttt agttttccca
     2101 caatttcgtc tatttgcaaa ttcagttccc atcttaaatt ataattactt acattattat
     2161 attcattaca attaccaaac tttaatattg aatctatctc ttcaataatg agatttatac
     2221 ttctagcaat tttttgttta tcttctcttc caatttttaa tacattataa aatttatcaa
     2281 aagcctttat ttttctcata tttctactat attttttata tataaagcta ctattttgaa
     2341 taaactcgta aggataaatt tcttgtaata aataccttaa agactttgaa tttataatgc
     2401 ttgaaaagaa atcatatcct ttttcagtca aattatgtgc ttcatctact attatatttt
     2461 ctaaaggttt ttcatcctta tatggccatt tagctaatag tgaatgattt actactgtta
     2521 tatgttcttc ttttaattct tctattctgt ttttatataa acaatctttt ttgcattttt
     2581 taggtctgca catatttggg tcacaactta catttcttaa gtgagtactt atttccttga
     2641 agttgtcaaa cactaaataa tttatttctt ctatatctcc atacttgcca ccttcaacta
     2701 atctcttcaa aaatattaaa gataaaattt ctcctttagt agggttttga gactcataat
     2761 catctatata tgcttccagt ctatctatac aaatatagtt attttttccc tttatatatc
     2821 cgtaacttac ttttccattt agacccaaag aatctaacac atttggaata tctttattta
     2881 ttaattgtat ctgcaattcc tttgtgtcag tagaaattaa taatcttttt ttattaattc
     2941 tagcctctaa tattgcaggc aataaatatc ctacactttt acctatacca gttggtgcct
     3001 ctatacatgc aattttttct tcatcttcgc tatttctaaa caactctctt attgttttag
     3061 taagctcata ttgaccaggt ctatattcat atgtaaatcc ttctttattc tcccaaatag
     3121 ttttgtattt taataattct tcataatttt tttcttcttc atttaaaatt tttaaggttt
     3181 ctctttcctt cttcttttct tcttttgagt caaatatatt atattctttt tttatattta
     3241 tattatttga taaatcataa tttgcctctt ctaaaaattt gctccattcc catgttggaa
     3301 gattaaattt tttaagatat gaatttattt taaaactcaa tggctccaaa gtagtttttt
     3361 catagttatt aaattttact aaaaggcaat ttacaatatt tattatatca atagcatctg
     3421 ataaagctct attttccact ttagaattac aatttgttaa agtatttttt aagtattcta
     3481 agctataatc tttatgatat ggttctaaaa taactgctaa ttcaattaaa tcaataaatt
     3541 tgttttttaa ctttggcata tgatactcaa gaaacttttt tttcagactt aaatcatgac
     3601 atataatgaa actatcttct acaaaattta caagtctatc ttccaccagt tctatttcat
     3661 tagctatttc taaatcattt ttatctaaat ttttacatac tgagaatact tctacaggta
     3721 cctcaaattt gttttttatt aatgattcat aggtatatat tttccagtct ttaaccttga
     3781 cagctccaac ttctaaaatt tctgaattta aacaatctaa tccactaact tctatatcta
     3841 aaaaaacaac atcattcaat acacttatta tattatccat ttttatatcc cttcaagtta
     3901 aaccagccta acttatttac aatcatttct ctttatattt tatcatttat atacacttta
     3961 tttaagataa ttaatatcaa ctttatatct tacagtaaac ttctttcatt tattatttgt
     4021 atatgtgaat atttttaact ataaatattc aaactatatt ataagaaata tactttaaat
     4081 tttaaataag aggtgaaatt gtgaaaaaag atagcctaaa aaaatacatt atgataggag
     4141 catttgctct aatacttttt ggaattgcta gtataaattt taaatcatta gataaaacaa
     4201 aaactcaaat ttctagtcca acactcgaca cacatgaata tgattggtat tttaacccta
     4261 gggaggatgg taaacagcca tcacctataa aagaagctga tttttttaaa aaatacggag
     4321 cttattatgt aggaaatccc aatgaaaaag ttatatatct atcatttgat gctggatatg
     4381 aaagtggaaa cactccaaaa ttattagata cgcttaaaaa acacaatgct aaagctcaat
     4441 ttttcgtagt tgaaagttat ataaaaagca atccagagtt aataaagcgt atggaaaaag
     4501 aaggacattt agtttgtaat cattcaaaaa gccatccatc aatggcaggt attacagatt
     4561 ttgaaaaatt caaagaagaa attacaagtg tagaaaaagc atacaaagat gttactggaa
     4621 aagaaatgcc taagtatttt agacctccaa tgggtaaatt tagcgaacaa tctttaaaat
     4681 atacacaaga tttaggatat aaatcaatat tttggagttt tgcttatgta gattggtatg
     4741 aaaagaaaca acctactcat gaatttgcca aaaacaaaat ttattcaaga actcatcctg
     4801 gtgcaatagt tttactgcat ccaaattcat caacaaatac tgagatatta gatgaggttc
     4861 ttacacattg ggaaaaagaa ggttataaac ttaaaacact tgattattta aataataaaa
     4921 aatagtatca taaatttaaa aaaactctat catgaattat agtaaaaata tagttattta
     4981 taaatacttt aattctcgat agagtttttt attttttata gctatttaaa aagaattgtc
     5041 cattcattta tctctttgta tcctatatta tgatatattt tacctgctac atcattatta
     5101 taaaaaagac atggaacttt tccttctaac aacaattctt tactcaaatt gtaaaccata
     5161 taacttgcaa gtccttttcc cctatatctt ttatctgtac ttacagagac caccattgcc
     5221 aaaaaactag tttccatacc agttgacaca gtgctaatca tagtatcatc atttctaata
     5281 aaatatgctc ttacatttcc ctcttttaaa tgaacttttc tttcttctat gtaattttta
     5341 cttactttat agtctgacct atttaaaagt tttcctattt catcaatatc tttttcctga
     5401 gcattttcta ttttatactc cttcatgttg gaaaaatcta tttcttttat ttcttttaat
     5461 acacaaaatt tattatctag tttttcataa aaatctttgt atttacttat tagtctatct
     5521 attacacatt tttttccact tatgctttct acatctaaat cttttatatg attcttcatt
     5581 tctcctatat taaaattatt tttaaaacta taaattataa gtgttgactt attttttaat
     5641 attatagagg ttatatttcc atcttctacc tgagaccata tatcttgata ttgagagcta
     5701 aatccataat tctcaacgta tccaattatg aataaattta aactttcttc atgtgataca
     5761 tattgccaaa attctttttc taaagtatta tctattttta caatcaagca gatatcctcc
     5821 ttctatgtta ataatgatat accttataat ttatagtatc atttaaaatc attatattct
     5881 accaaatatt ctaaattttt aaatatctat gcaatatgtt cgtatttatt tttatattct
     5941 gttactgctt cactccaagc ttcttctact gaaatacctc tcttatttgc aattttttgt
     6001 gctaattcta ttattttcat agcttttctt gatatattca tatatattcc tcctctaaat
     6061 tatcataagt tattttaaag ttaaatttct atagtcatgt tatatattta tttacttata
     6121 tcttactaat tatttatgta ctaaatatga actacaatag aagaaattta gaacttaata
     6181 aaacataaaa tttatataca gttcatatat atttgtcata tcacaagaca agtgatataa
     6241 tttattatca ttttactggg ggtgatatgc tatgaaaata agagctgaat atacatgtct
     6301 tcttgaaatt gtacatgaca taatcaaagg aaaatggaaa actatcctta tatttgaatt
     6361 aagacaatct aataaaacat tttctgaatt gcaacataat atttatggaa taaatcaaaa
     6421 aatgttgatt caacaattaa aagagttacg tgattttggg attattgata aaataagttc
     6481 tgctggatat ccattacatg ttgaatattt tcttactaat cgtggtaaaa aaatgttaaa
     6541 agcagtggaa ataatgcaag aaataggaat cgaatatatg cttgaacatg gtcaacaaga
     6601 aattctagat aataaaggaa tttgctacaa taagtaatcc tatacatacc aaaaagtaag
     6661 taatttacat tttttacaat agtattataa taaaaataaa taggaggtat aatcatgtct
     6721 atagctttaa tattgattga tattcaaaat gattatttta aaaatggaaa atgtgaatta
     6781 tttcaatcag aagaaactgc tgaaaatgct aaaaaaatac tactgttttt tagaaaaaac
     6841 aatttaccag ttattcatat acagcatata tcaacagata aaacagcttc tttttttctt
     6901 cctaatactc atggttcaga aataaataaa attgtttttc cactagataa tgaagaaatt
     6961 ataactaaac acacaccaga tagtttcttt gaaacagatt tgcaaagtat ccttgagaaa
     7021 aaaaatatta ctaatctagt aatctgtgga atgatgagcc atatgtgtat tgatacaagt
     7081 gtaagaacag caaagaaact tcgatacgac ataactctaa taagcgatgc atgtacaacg
     7141 aagaatttat cttggaataa tatagaaatt aatgcaaata ctgtacatca agtattcatg
     7201 gcatcactac agaacagttt tgcagatgta aaaaacacag ataaattttt atctaactat
     7261 cacaaataaa aacatacact atgttaaaag agcaagtttg atttatttaa gcttgctctt
     7321 taatcattta aaattagatg ctttctatca tttttatata cataatatac gtttatacat
     7381 tttatattca tatataacta ttatataaat tttaaacttt actatattca cataaaaaat
     7441 gtagtattat agtatatata atattatata gaagggggtg ctagataaat gaaccatcat
     7501 atattgattc aatttgaata tatagcaaga atcattactg ctggtttctg tggggcttta
     7561 attggatatg agagaaagaa tagactaaaa gaagctggaa tacgcactca ttttatagtg
     7621 gcattagctt cagcacttat aatcattgtt tccaagtatg gatttaatga tatagtgggt
     7681 actccaggta ttggtctaga cccagcccgc gttgcagcac aagttgtcag tggtataggt
     7741 tttttaggtg ctggattaat atttattaga aatcaatcag taagtggtct tactacagct
     7801 gctggtatat gggcaacagc tggtacaggt cttgccattg gctctggatt atacttagtt
     7861 ggtattgttt caagtatcat tattgttatt gtacagataa cacttcatag agataggaaa
     7921 tggatgaaac tccctacagc agagcaagtt tctcttaaaa tttctaacag cactgattcc
     7981 atagaatata ttgaaggtaa atttaaaaaa tctaatattg aaattataaa catgaatatt
     8041 aaacgccttg atggggattg gttagaagta gttatatata ctaagttacc taaaggatat
     8101 aaaaaaacaa atttattaaa attatttagc gataatcctc ttatagaaac tttagaaata
     8161 taatataaaa attgaagctt aaaaataata atatatttaa tcaaggtcaa tatataaata
     8221 attacgggat gagtctatat aaaattcatc ccttgttttt tgccattcat atatattttt
     8281 tcaagatatt tttgttcatc tattatctag ccaagtaact cttgtgaact aaacttttta
     8341 atacaaaaac ttcaatacaa aactaaatat aatttttatt aaatattcta catgtatagt
     8401 ttatttcttg agtgaaaaat agatttcata ttgttaagat actgttaaat atttcaattt
     8461 tctgacaagt atgttgaaca ataacttatc ctagtgtatt attttagttg tagaataaaa
     8521 ctaaatcggc aaaactagag aaatttagtg acgcaaagct atagggacta acgcttataa
     8581 aataaactat gagttatgtc agccagttgc caaaaagata ttgttctttt tgttttatga
     8641 aagtttttta gggggatagt aatatatatg tttagagatg aaatggataa atgtacacac
     8701 atgttaactg cttatatcag tagtttatat gattattgtg attttataga tacacagcta
     8761 gatgatttta tactagagta cggagaaaat gtagtagaat cttgtttaca tcaagtgatg
     8821 gtattggtaa gtaagtataa ttaaatagaa attgttttct agagaaccct ttttagtttt
     8881 atctacattt aaaaatgtta ttatattaaa aaactaatct cccctatatg caaagttttc
     8941 ttccatataa caatttcttc ccatttatac tttttcactt gtatctttaa taaaattcaa
     9001 cttcaaatat taatatactt caaaaattat tctatttctt atctttacac caattcctat
     9061 cagtattatc ctttatatag gttctaacta tttctccaca atctaaacat aaatctgaat
     9121 atatagtaga ttgtactgga aaagttttat ttataacttt atctaatttt ccatctcctc
     9181 tatattttaa tccaatagtt tcagcatata tgccaccagt tgttaaaatt cccttttcaa
     9241 tatttacact tccacaatta gaacatttca catttataac cccctaaaca attatttttt
     9301 catgctatct tataatttaa aatataattt gctaccgatt ttataacaca gtggcaaatc
     9361 aacatttttt cattctattt accatctaat ccattgaaat atagctattt agttatagga
     9421 acttgaattt ccgttacaaa ctcctctaca attccagtct catgtatatc tatcttatag
     9481 atttctatag ggtcagcaat tatcttataa ttattttctt ctataaattt aaacaccttc
     9541 tccatatata tcttattatt agaattactc ccagtataat ttaaagttac ataatatcct
     9601 tcatcaaaaa ctatattata tactttctca ttactttcca gaaaacaaaa tacagattta
     9661 aactcattaa atataccttt attaattgct tcagtagaaa aggcagaacc aatattgttg
     9721 tttccaagta tattaaatct atcttcatat tctttctgaa gtttttgaat taaaaaatcg
     9781 aagtcttcat ccctctttat atcagcattt aattctaaag cttttctttt ttctatatat
     9841 acaacctcta tctcatctat ttttgtattt tgaattacac tttcaattga actcaatctt
     9901 tttataatat tttccttatg gcttataaat tcagctattt ttttatcaat taaatcgagt
     9961 tcttcattta aaatattttt cgtagactct atacttctgt catctaggta ttcttttatt
    10021 ttcttcattg gaaagttcaa gcttctaaat tcttttatta aatttaattt ccatatatct
    10081 gatatattat acattctata tccatttata tctctaactg gtcttagaat gcctatttct
    10141 tcataataca ttaatgaatc tctacctatt ccatatattt tagatatctc tcctatttta
    10201 tagtaatctt tcatttatat aataaactcc tccgaaatct tatttttatt ttaaatcaac
    10261 attattactc tataatacta tagtattaga atatactaaa aaaatcttta aaacaaggat
    10321 a
//
LOCUS       DAMKNB010000107        10255 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.113, whole genome shotgun sequence.
ACCESSION   DAMKNB010000107 DAMKNB010000000
VERSION     DAMKNB010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 10255)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10255)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10255
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.113"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            complement(76..264)
                     /locus_tag="PC494_003209"
     CDS             complement(76..264)
                     /locus_tag="PC494_003209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3913684.1"
                     /translation="MNYHTKEELVEALRVVSSSIINCGKGQKKFSEETSHHTRFKNII
                     EVMYISKSLIMDEISKRD"
     gene            598..1566
                     /locus_tag="PC494_003210"
     CDS             598..1566
                     /locus_tag="PC494_003210"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HDF3913685.1"
                     /translation="MAIKPRKISIVGSGHVGSHCGFSLITQGVCDELFMIDIDESKSK
                     AQALDLADAVSYLPHKVHIEKGTFSDCKDSDIVVISVADSSEGPLRRQNTTRLDLLRP
                     TIGMIKSIVKPIVDSGFDGIFVVISNPVDVVTNYIWEKSGFPKNKVIGTGTALDSTRL
                     RRILSEETGIAQQSIQAYSMGEHGDSQMVPWSHVSIGGKPILDMIKDNPSTYSNLDLP
                     SIVEKNKKTGISIINGKDCTEFGIGTALVEIVKAILHNEKKVLPVSTLLEGQYNERNV
                     FAGVPCVIGKDGIEEIIEINMTEYEQNEFNKSCSVLREYIALSKTL"
     gene            complement(1683..2813)
                     /locus_tag="PC494_003211"
     CDS             complement(1683..2813)
                     /locus_tag="PC494_003211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF3913686.1"
                     /translation="MNLKDFNGKRLKSARIFRAKTIEQLSKETKINKKDLKAFEENKY
                     VPNIENTLKLSNILNFPKEYFYKNENINIVVEDSHFNPQSKLPRVEEISYREKIIIIH
                     KIYSFMENYIKFPKENLPNRKVMSDININDIESLAYKTREFWDLNSTPIVNMVSLLES
                     KGIIISGMNVDRKGATIFTQKQRISKESKYLISLGNDKKSASIRNYTLACELGYIISS
                     ELRIPSKQFSEDEYACAFLLPKESFLKDLTHPEDLDYYVELKKKWIVPISAMIFRAYN
                     LEKINYKKYNYLMNEMDKKGWLIEEPLDKMKGSSPTYLKRAVELLIENKIMSVNSIVS
                     SLEEFRINLYPEDLELLMGLKKGLLSQEVNKKSKVIKFDGKK"
     gene            complement(2966..3919)
                     /gene="msrA"
                     /locus_tag="PC494_003212"
     CDS             complement(2966..3919)
                     /gene="msrA"
                     /locus_tag="PC494_003212"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HDF3913687.1"
                     /translation="MIKLATFAGGCFWCMVKPFDKYDGVIKVVSGYTGGHVENPTYQE
                     VCSGTTGHLEAIQITYDDDIISYDELLNIFWKQINPTDDGGQFGDRGTQYKTAIFYHD
                     EEQKNIALESREHLENSKIFDSKIVTDIIPATKFYEAEENHQDYYKKRPLNYNMYYKG
                     SGRYNFVKSHWDGNNINREELKKTLTPIQFEVTQNDMTEVPFENEYYDNNKEGIYVDI
                     VSGEVLFSSKDKFDSGCGWPSFSKPVIDKSIIERSDFSQGMYRVEVRSAKGNSHLGHV
                     FDDGPKELGGLRYCINSASLKFIPRENMEALGYGEYLKLFE"
     gene            complement(4043..4948)
                     /locus_tag="PC494_003213"
     CDS             complement(4043..4948)
                     /locus_tag="PC494_003213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
                     /protein_id="HDF3913688.1"
                     /translation="MKNSNFNILAFDGGGLKGALSISILERIVKEYPNLLNNINMFGG
                     TSTGSLIALGLAYGVSPKEIKELYSIENSKYIFNKSYAEILRPKYENKNLKEVLLSIF
                     PEELELKDLNKLVMIPSFYIGNEENAWKPVFYNNMPNSFTKTSKVVDVAMASSAAPVF
                     FPTYNRHVDGGIIATDPSLACIIHAIDSGFKLKNTRLFSIGTGYVYNSIKADTTEWGA
                     IDWIINKEPDLPIISITLEGNSQMSQLFSQKLLGDNYYRLNPKMEKDVAMDDCDALEY
                     LMSLGENCDIKDAFGWIKKKSFYRN"
     gene            complement(5319..6911)
                     /gene="hcp"
                     /locus_tag="PC494_003214"
                     /gene_synonym="priS"
     CDS             complement(5319..6911)
                     /gene="hcp"
                     /locus_tag="PC494_003214"
                     /gene_synonym="priS"
                     /EC_number="1.7.99.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxylamine reductase"
                     /protein_id="HDF3913689.1"
                     /translation="MEKMFCFQCEQTAGGKGCTINGVCGKKGGTANLQDELTGVLIGL
                     SRATIGNKNRPTSETDKIMIEGLFTTITNVSFDDEAIKRQIEKTEVEKSKLVPRCSDC
                     STTCNRNDNYDMKDLWNDNEDIRSLKSLILFGLRGMAAYAYHAMVLGYTDKDVNEFFY
                     EGLIAVGGDLSIDELLGLVMKTGEINLKCMELLDRANTETYGTPEPTQVSMKIEKGPF
                     IVVTGHDLYDLHKLLEQTKDKGINIYTHGELLPAHAYPKLKEYKHLKGNFGTAWQNQQ
                     KEFDNIPAPILFTTNCLMPVKDSYRDRVFTTEVVAYPGMVHIDEDKDFSSVIEKALEL
                     GGYREDVHMTGINGGDTLTTGFARGTVSSVQDKVVDAVKSGAIRHFLLVGGCDGAKPG
                     RNYYTEFVKQAPKDTVILTLACGKYRFNDLDLGDIGGLPRLMDMGQCNDAYSAIKVAV
                     SLANAFECGVNDLPLSMVLSWYEQKAVCILLTLLHLGIKNIYIGPSLPAFLSKNVLDI
                     LVDKFALTPISTPEEDMKKILG"
     gene            complement(6971..7696)
                     /locus_tag="PC494_003215"
     CDS             complement(6971..7696)
                     /locus_tag="PC494_003215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HDF3913690.1"
                     /translation="MMRKIIKIDEEKCNGCGLCVEACHEEAIGMVNGKAKLLRDDYCD
                     GLGDCLPTCPTNAISFEYREAAEYDEAAVKANMEAKKAQKKTLACGCPGSQSKSINRE
                     VSNSTSISNDIVEIKGSQLNQWPVQIKLVPTNASYLKNASLLIAADCTAYAYGNFHNK
                     FMKNKVTLIGCPKLDEVDYAEKLTEILKENDIKNIVVTRMEVPCCGGIVNAVKTALQN
                     SGKMIPWQIVTISVDGKIVDGEI"
     gene            7837..8565
                     /locus_tag="PC494_003216"
     CDS             7837..8565
                     /locus_tag="PC494_003216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HDF3913691.1"
                     /translation="MKTNYRLHMQQGSDYLKKFLEKHIDLLKKIPLFEGIKSDELEEM
                     LECLGVVDKTYPKDSIIFSVGSEVTSIGIMLKGSAHIIKEDIEGNRNIVAELLPGDLF
                     GEVFACTRLHKSNVTVTTTSSCEVLFIKFKSVTGICSSACVFHNRLVENMLQLIAEKN
                     ILLHNKIELLSRKTTREKLLMYFSKQIEQTGSHQFTIPFSRNEMADFLCVDRSSMSRE
                     LGKMRDEGLLSFNKNKFEIFYFQK"
     gene            complement(8729..10000)
                     /locus_tag="PC494_003217"
                     /pseudo
     CDS             complement(8729..10000)
                     /locus_tag="PC494_003217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017416360.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="dicarboxylate/amino acid:cation symporter"
BASE COUNT         3413 a         1731 c         1183 g         3928 t
ORIGIN      
        1 ttataacatg tatgtttact tattttctta tataataaaa tgtatattaa aacatgttaa
       61 attgcaaaat aagcttcaat ctcttttact aatttcatcc attattaatg attttgaaat
      121 atacattact tctataatat tcttaaaacg tgtatgatga gatgtctcct cagaaaattt
      181 cttctgtcct tttccacaat taataatact tgaagatact actctcagtg cttccaccaa
      241 ttcttctttt gtatgataat tcataaccat ttactccttt attttttaat ttagagaaac
      301 agtatatctc aatttaatat cattataaac tgacatcatt attatttata cacatctttt
      361 agcacttaaa tattctaact atcagtgaca ttacatattt taataattat taatatacat
      421 ataatacttt aatattcact aatagagagt atattaacat tgctttttta aaaattttag
      481 tataaaatca tattaaataa attttctgaa ataatagaat attaaaatat ccaaaaacag
      541 cttttaataa catctataat tttcaatgta tcgttatttt agggggagtg atttaaaatg
      601 gcaataaagc caagaaaaat atctattgta ggttcagggc atgttggttc tcattgtgga
      661 tttagtttaa taactcaagg agtttgtgat gaactcttta tgattgatat agatgaatct
      721 aaatcaaaag ctcaagcttt agatttagct gatgcagttt catatctgcc acataaagta
      781 catatagaaa aaggaacttt ttctgactgt aaagattctg acatagtagt gataagtgtt
      841 gcagactctt cagaagggcc tttacgtaga caaaacacaa ctagattaga tttactaaga
      901 ccaactattg gaatgataaa atctatagta aaacccatag ttgattctgg ctttgatggt
      961 atatttgtag tcatatctaa tcctgttgat gtagttacaa attatatttg ggaaaaatct
     1021 ggctttccta aaaacaaagt cattggaact ggaacagctt tagattcaac aagacttaga
     1081 aggattttat ctgaagaaac tggaatcgct caacaatcaa ttcaagctta ttctatgggt
     1141 gaacatggag attctcaaat ggttccttgg tctcatgttt caattggtgg taaaccaatc
     1201 ttagacatga taaaagacaa cccaagtact tatagcaatt tagacttacc atcaatagtt
     1261 gaaaaaaata aaaaaacagg aataagtata ataaatggta aagattgtac agaatttggt
     1321 ataggtactg ctttagtaga aattgtaaaa gctatactac acaatgagaa aaaagttctt
     1381 ccagtttcta cattactaga aggtcaatat aacgaaagaa atgtatttgc aggtgttcca
     1441 tgtgttatag gaaaagatgg tattgaagaa attattgaaa tcaatatgac tgaatatgag
     1501 caaaacgaat ttaataaatc ttgttctgtt ttaagggaat atattgcact ttcaaaaaca
     1561 ctttagattc aatattcttt cttacactaa aagcaggtaa atgacttatt gaaaaaactt
     1621 ttaactaagt taatgtttaa atcatttgta cctgctttta attttaatac taaaatataa
     1681 acctattttt taccatcaaa ttttataact ttactttttt tatttacctc ttgagataac
     1741 aatccttttt tcaatcccat caataattct aagtcttctg gataaagatt tattcgaaat
     1801 tcctctaaac ttgatactat actatttaca ctcattattt tattttctat caataattca
     1861 actgctcttt ttaaatacgt tgggcttgaa cctttcattt tgtctagtgg ttcttctatc
     1921 aaccagcctt ttttatccat ttcattcata agataattgt attttttgta atttatcttt
     1981 tctagattat atgctctaaa aatcatagca gatataggta caatccattt tttctttagt
     2041 tctacataat aatctaaatc ttctggatga gtcaaatctt ttaaaaaact ctcttttggc
     2101 aataaaaatg cacaggcata ctcatcttct gaaaattgct tacttggtat tcttaattca
     2161 cttgatatta tatatccaag ttcacatgcc aaagtataat ttctaattga tgctgacttt
     2221 ttgtcattac ccagagatat tagatattta gattctttac taattctctg tttttgagta
     2281 aagatagttg ccccttttct atctacattc atacctgata ttataatccc tttagactct
     2341 aacaaactta ccatatttac tattggagta ctatttaaat cccaaaactc tctagtctta
     2401 tatgcaagag attctatatc atttatatta atatctgaca ttacttttct atttggcaag
     2461 ttttcttttg gaaacttaat ataattctcc ataaatgaat atattttatg tattataatt
     2521 attttttctc tataagaaat ctcttctact ctaggtagtt tagattgagg gttaaagtgg
     2581 ctatcctcta caacgatatt tatattttca tttttataaa aatactcttt tggaaaattt
     2641 aatatattag ataattttaa tgtattttct atatttggta catacttatt ttcctcaaaa
     2701 gcttttaaat cttttttatt tattttagtt tctttagaca actgttctat cgtctttgct
     2761 ctaaaaattc tagctgattt taatctcttt ccattaaagt cttttaaatt catttgtttt
     2821 ctctctttca aaattaaatt cttaatctat tggtataaat aagattacaa ttaataattt
     2881 atcatactat tgacaaaaaa acaaaaggtg aaaatatttt tttagatttt caccttttag
     2941 ataagtttat aataaatatt cctaattact caaaaagttt taaatattct ccatatccta
     3001 aagcttccat attttctctt ggtataaatt taagagaagc agaatttata caatatctta
     3061 aacctccaag ttcttttgga ccatcatcaa atacatgacc taaatgagaa tttcctttag
     3121 cacttcttac ttcaactctg tacatacctt gtgagaaatc acttctctca atgatagatt
     3181 tatctataac tggctttgaa aaacttggcc acccacatcc agaatcaaat ttatcttttg
     3241 aagaaaataa cacttctcca cttacaatat caacataaat tccctctttg ttattgtcat
     3301 aatattcatt ttcaaaaggt acttctgtca tatcattttg agtaacttca aattgtatag
     3361 gagttaaagt cttttttaac tcttccctat ttatattgtt tccatcccaa tgacttttta
     3421 caaaattata tcttccggac cctttataat acatattgta gtttaatggt cttttcttat
     3481 aataatcctg atgattttct tctgcttcgt agaatttagt tgctggaatt atatcagtca
     3541 ctattttact atcaaatatt ttactatttt ccagatgttc tcttgactct aaagctatat
     3601 ttttttgttc ttcatcatga taaaatatag cagtcttata ttgagttccc ctatcaccaa
     3661 attgtccacc atcatctgta ggattaatct gtttccagaa gatatttaga agttcatcat
     3721 aacttattat atcatcatca tatgttattt gaattgcttc taaatgacca gtagttcctg
     3781 agcatacctc ttgatatgta gggttttcaa catgaccacc tgtatatcca gaaactactt
     3841 taataactcc atcatactta tcaaaaggtt ttaccataca ccaaaaacat ccacctgcaa
     3901 aagtagcaag ttttatcatt ttcatcactc cttaaataaa ttatacttta tttattccct
     3961 aagaagtaac ttaataatct gcattttatt atttttacct actcaatgaa atcatgtgta
     4021 aaaatacaat tgcaaattga atctaatttc tataaaagct ctttttcttt atccatccaa
     4081 aagcatcttt tatatcacaa ttttctccta aagacattag atattctaat gcatcacaat
     4141 catccatagc tacatctttt tccatcttag gatttaatct atagtaatta tctccaagaa
     4201 gtttttgaga aaataactga ctcatttgag aatttccttc taaggtaata gatataattg
     4261 gtaaatcggg ttctttatta attatccagt caatagctcc ccattcagta gtatctgcct
     4321 ttatactgtt atatacatat ccagtcccta ttgaaaaaag tcttgtattc ttaagtttaa
     4381 atccactgtc aatggcatga attatacacg ctaaactcgg gtcagttgct attattcctc
     4441 catcaacatg acgattatat gttggaaaaa ataccggagc agcactactt gccattgcta
     4501 catctacaac tttgctagtc tttgtaaaag aatttggcat attgttataa aacactggtt
     4561 tccatgcatt ttcctcattt cctatataaa aacttggtat cattactaat ttatttaaat
     4621 cttttaattc tagttcctct ggaaatatac ttaataaaac ttcttttaag tttttgtttt
     4681 catactttgg tctgagtatt tctgcataac ttttattaaa aatatacttt gaattttcaa
     4741 ttgagtaaag ttcttttatc tctttagggc ttacaccata cgcaagccct agtgcaatta
     4801 gactccctgt agatgtacct ccaaacatat ttatattgtt taatagattt ggatactctt
     4861 ttactatcct ctcaagtatg gatatactca atgccccttt taatccacca ccatcaaatg
     4921 ccaatatatt aaaattagaa tttttcatat acatataccc ccacataaaa caccttatat
     4981 tttaaatttt aatcaaaata atttcactat agtatatata ttttatgcaa gttacatatt
     5041 acaatgttcc tcttttaata tttaagttac attcaaacct ttaatactta aaataaaata
     5101 tataagatat tatatatcta agtattataa atttaataca aaaattctta aaagaatata
     5161 ctgaaagcag gtttattttt caattattac aaaaaataaa taaagggtca tctcaaaatt
     5221 gattttttaa tcaaatttta agtttaaccc cttatcttaa ttgtggcata cttaaaaata
     5281 ttttaactat aaatatcttt aagtatagat atatttattt atcctaaaat cttcttcata
     5341 tcttcttcag gagtagatat aggtgtcaat gcaaatttat caaccaatat atctaataca
     5401 ttcttagata agaatgctgg taaagaaggc cctatataga tatttttgat acctaaatga
     5461 agtagtgtaa gaagtataca aacagctttc tgctcatacc atgacagtac catgctaaga
     5521 ggcaaatcat ttactccaca ttcaaaagca tttgccaatg aaactgccac tttaattgca
     5581 ctataagcat cattacattg tcccatatcc attaaacgag gtaagccacc tatatcccca
     5641 aggtctaaat cattaaatct atattttcca catgcaagtg tcaatataac agtgtcttta
     5701 ggagcttgtt ttacaaattc agtgtaataa tttcttccag gttttgcacc atcacaacct
     5761 ccaaccaata aaaagtgtct tatagctcca ctctttacag catctactac tttatcttgt
     5821 acagatgaaa ctgtacctct tgcaaaacca gtagttaatg tatctcctcc attaatacca
     5881 gtcatatgaa catcttctct atatcctcca agttcaagag ctttttctat tacactagaa
     5941 aaatctttat cttcatcaat atgaaccata cctggataag caactacttc tgtagtaaat
     6001 actctatctc tataactatc tttaacaggc attaaacagt ttgttgtaaa taatattgga
     6061 gcaggaatat tatcaaattc tttttgctgg ttttgccatg ctgtaccaaa attgcctttt
     6121 agatgtttat attcttttag ttttggatat gcatgtgctg gtaataactc accatgagta
     6181 tatatattta tacccttatc tttcgtttgt tctaataatt tgtgtaaatc ataaaggtca
     6241 tgtcctgtaa ctacaataaa tggccctttc tcgattttca tagatacctg agtcggttct
     6301 ggtgttccat aagtttcagt atttgctcta tcaagcaatt ccatacattt taagtttatt
     6361 tctccagttt tcataactag acctaaaagt tcgtcaatag acaagtctcc tccaactgct
     6421 attaatcctt catagaaaaa ttcatttacg tctttgtctg tataaccaag taccattgca
     6481 tgatatgcat aggcagccat acctcttaat ccaaataaga ttaatgattt taatgaacgt
     6541 atgtcctcat tatcattcca taaatccttc atatcatagt tatcatttct attacaagtt
     6601 gttgaacaat ctgaacatct aggtacaagt ttactttttt ctacctcagt tttttcaatt
     6661 tgtcttttta tagcttcatc atcaaaactt acattcgtta tagtagtgaa tagcccctct
     6721 atcataattt tatctgtttc acttgttggt ctattcttat ttccaatagt tgctcttgaa
     6781 agaccaatca acactcctgt aagttcgtct tgtaagttag ctgtaccccc ctttttacca
     6841 cagacaccat ttatagtaca acctttacct cctgctgttt gttcacattg aaaacaaaac
     6901 attttttcca ttttttattc ctcccttttt atttattaaa atttattata tttttctata
     6961 attcacttaa ttaaatttct ccatctacaa tttttccatc tacagatata gtaactattt
     7021 gccatggtat catttttcca ctattttgta gagctgtctt aacagcattt actataccac
     7081 cacagcaagg aacttccata cgtgttacta ctatattttt aatatcattt tcttttaaaa
     7141 tctctgtaag tttttcagca tagtcaactt catcaagttt agggcatccg attaatgtaa
     7201 ccttattttt cataaattta ttatgaaaat ttccatatgc atacgctgta cagtctgctg
     7261 ctattaaaag acttgcattc tttaaatatg atgcattagt tggtactaat tttatttgta
     7321 ctggccattg attaagttga gaacctttta tctctactat atcattgctt atagacgtac
     7381 tatttgaaac ctctctattt attgatttag actgagaacc tggacatcca catgctaaag
     7441 ttttcttttg tgctttcttt gcttccatat ttgcttttac tgcagcttca tcatattctg
     7501 ctgcttctct atactcaaat gaaatcgcat ttgttggaca agttggcaga caatctccca
     7561 gcccatcaca atagtcatct cttaaaagtt ttgcttttcc atttaccatt cctatagctt
     7621 cttcatgaca agcttcaaca catagtccac aaccattaca cttttcctca tcaattttaa
     7681 ttatttttct catcatttat atcacctcat aaaatttttt taatttaaag tattgatttc
     7741 ttatatattt atttttaata cctatatttc tttatttcaa atttcttgta gtaggatttt
     7801 tatatcccct tgcttttata aacttagtat agtacaatga aaacaaatta tcggttgcat
     7861 atgcaacaag gaagtgatta tttgaaaaaa tttttagaaa agcatataga cctacttaaa
     7921 aaaattcctc tatttgaagg aattaaaagt gatgaacttg aagaaatgtt ggaatgttta
     7981 ggtgttgtag ataagactta cccaaaagat agtataatat tctctgttgg aagtgaagtt
     8041 acttctattg gaattatgct taaaggaagt gctcatataa taaaggaaga tatcgaaggg
     8101 aataggaata ttgtagctga actcttgcct ggagatttat ttggagaggt attcgcatgt
     8161 actagactac ataaaagtaa tgttacagta accacaacat cttcttgcga agttttattt
     8221 ataaagttta aaagtgtaac tggtatttgt tcatctgcat gtgtatttca taataggctt
     8281 gttgaaaata tgctacaatt aatagctgaa aaaaacattt tacttcacaa taaaatagaa
     8341 ttactttctc gtaaaacaac tcgcgagaaa ttgcttatgt atttttcaaa acaaatagaa
     8401 caaacaggta gccaccagtt tacaattccc ttttcaagaa atgaaatggc tgatttttta
     8461 tgtgttgaca gaagttctat gtcaagagag cttggcaaga tgcgagatga aggcttgtta
     8521 tcttttaaca aaaataaatt tgaaatcttt tattttcaaa aataaaatag atatttaaac
     8581 atatttattt caatatatac tatattagtt gattcaaatt ataaatatca tatttgaatc
     8641 ttaaatttat atttttactt aaaaagttaa taggtatcta atttattaaa attaagatac
     8701 ctattaactt tattaattaa gtgtacaatt agcttatttt ctttgtagta attgctgttt
     8761 tatctataag ccaatctttt ccttctacta atcttgaaac taacattgat gatactgtat
     8821 ttccagttgt atttaatata gtattaggaa tatcagttat agtagttata actgttaaca
     8881 gtggaattgc ctccactgga aaaccgaaga tgctaaccac gagcatctca ccaataagtc
     8941 agccacctgc tacaggagcc ataaatactc caacaacaaa tacagttata aataattgac
     9001 ctatcgttgc tggatttgcc attccactac ctaaaatacc tgataaaaat gccactttta
     9061 ttattactgc taaaactgcc ccatctttat gtatatttat tccaagaggt ataactgttt
     9121 ctgatatatc atcaggaact cctatatttt tactagcttc taaatttgat ggtatacatg
     9181 ctgaacttga agaagtagct agtgccgttg ctattggttt tatagcattt ctccagaatt
     9241 gtctaaaccc ttgttttcct gcagataaaa aagcatacag actgtaaaat aataagaaat
     9301 acatggctgc tgttagtgaa taaattacaa acacccttac atatccttga attattttac
     9361 ttccaagttc cccaattatt gtagctgtat aacagcctag ccctatagga gcataaagca
     9421 tgaatatact tactactttt aatattgctt ccgttccttc tgataaaagc tttcttattg
     9481 tatttcccct atctcccatc atagctattg ctgttccaat taaaactgca aatataacta
     9541 attgtagtaa attactactg gaaaataaat ctccaaaatt tttaactgta atacttgata
     9601 ctacttggtc taataacgtt ccttttgatt ctaaagtttc tgcatcttga gccaccatta
     9661 aattttttac acttgataca tctaatcctt tagacggatt aaataataat gcagatgtaa
     9721 tacctaaaaa tgcaattaca agtgttgttc ccataaatac tatagctgta cccttcatta
     9781 tttttccaaa tcgttccata ttttttatac tagcaacacc tgaagaaaca ctaagaaaaa
     9841 ctaatggtac tactatcatt aatagagcat ttatgaataa atctccaaat ggttttagta
     9901 ttgaagcttt tggaccaagt actaatccta ctatcgcccc tactatagta catgctaaaa
     9961 gtataattga tgacttataa ttttttaaaa agtccctcat ttatattttc ctttctaatg
    10021 ctttatatta taaattaccc caaatgctaa aaaaattaaa gcaaattatc taatgcgcat
    10081 taataatttt tgtaattttc cccaacagct actttagcaa atactggaat atatgtcaat
    10141 ttctatagtt tttttgtatt tttaacgttt tattaatagt tcatatctat atataaatat
    10201 taataaaatt ctgcttttaa aacttttttt ctagattaat tttaataaaa caaac
//
LOCUS       DAMKNB010000108        10147 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.114, whole genome shotgun sequence.
ACCESSION   DAMKNB010000108 DAMKNB010000000
VERSION     DAMKNB010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 10147)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10147)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10147
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.114"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            complement(5..1759)
                     /locus_tag="PC494_003218"
     CDS             complement(5..1759)
                     /locus_tag="PC494_003218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp23"
                     /protein_id="HDF3913692.1"
                     /translation="MYIMNKKFKKFSKKLSILILVLTMFLFNNLTANAQIKEDSIIGI
                     DRYETAGLIADRQTYDTVILVNGDKNLSDGLSSSGLAGAINAPILLTKKSEIPKATLN
                     RLDNKSLNVVKKVYIIGGYNTIENSVEKDIKRKGIQVERINGNNRIETSYNVAKKINE
                     VSSVKEVMLTNGFVGEADAMSIAPVVAKNKGAIILTDGKSVPFKTEGLNVYAIGGKSA
                     INEDLVNETKAIRIGGNDRFETNKKVMEKFYNGATDFYITNGYQLVDALTLSPLAKEK
                     PIVLVADGSNKGILKGAKSITKVGGIDANIYKQCLDMIKYNNMDMTPNILKHLTSVEG
                     NEVSEILIESDNLGVVVEKTNTNKFEFDYVSVTNEKNCTFSVYKENSSNNIKNGKLVV
                     SAKKKIDKKDSDLQDMNGDNMINANKDRMVNVIKIGVPDKMYSNFKVDVESGSVELYN
                     IKGGATVDVNDGIANIVDNNVTNPFNINTNSGISGVTAETISSEIKFRANNGIVNVTA
                     TNINGNISLFGSDNKDTFDGIFKLNLKKEPSNLHLKLIGNGINKLPEGWSKDYILGNG
                     QPIIEVKNNGINNISIGE"
     gene            complement(1977..2867)
                     /locus_tag="PC494_003219"
     CDS             complement(1977..2867)
                     /locus_tag="PC494_003219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HDF3913693.1"
                     /translation="MAKLTLEHIKGNTYYIPLPTIVGVYVDGKDAILIDSGNNKDTAR
                     QVLRLLEEHNLNPKLIINTHSNADHIGGNAYLKNQTKCKIATTKIEGYFTENPILESA
                     FLYGGYPSKALKNKFLLAKESEVDYIIPSNGKIVDTELEAISLPGHYFEMIGVRTPDN
                     VLFVADSLTPENIITKYHFFFLLDIDSQFKTLEKLRMLEADFFVPSHSVKTTDIKSLI
                     NINKKKMEEIIDNIKKVCYEPVMIDEVIEKMCDLYNVKLDANQYVLVGSTIRSYITYL
                     YENNMVEYIFDGGKMMIKAA"
     gene            3016..3876
                     /locus_tag="PC494_003220"
     CDS             3016..3876
                     /locus_tag="PC494_003220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HDF3913694.1"
                     /translation="MLLKKDRITFSEILILIVGCILMAISLNLFFNPHAIAAGGITGL
                     GVVLNSLFGVELWIVNLLLNVPLFIFAYKILSKKDCFKTVLGIIFLTIALKLTANMAT
                     LDITNDMYLAIISGSILMGVGQGLIFRINGSTGGTDLMALLLNKYFPTFSIPVLMGIV
                     DCVVVVLSGIVNRQVEIALYSTVALYILVKVSDLLIEGFNYSKSFTIISDLSKDISKK
                     IMEDLDRGATILKGEGAYTGENKNVLLVVVEKKEVVELKKLVKNVDPNAFIIITDIHE
                     ALGNGFKKIE"
     gene            4332..4898
                     /locus_tag="PC494_003221"
     CDS             4332..4898
                     /locus_tag="PC494_003221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerD family protein"
                     /protein_id="HDF3913695.1"
                     /translation="MSVSLQKGQRVSLVKDNNPVKNLVVGLGWDMNKLGKKNYDLDAF
                     AIALTNQDKMNVRGDLVYFGNLKHPSKAIIHTGDNLTGKGEGDDEQIIVNLEDIPEYV
                     HKIVFGVSIYKAKKRDQDFGQMNNSFIRLIDSNSKQELFKYNLQEDFSGKVTVLAGEI
                     YRRNEEWKFNALGIGQNEELRELINTYK"
     gene            4938..5519
                     /locus_tag="PC494_003222"
     CDS             4938..5519
                     /locus_tag="PC494_003222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerD family protein"
                     /protein_id="HDF3913696.1"
                     /translation="MGITLAKGQKVSLTKSNPGLKKVIVGLGWDINKYDGGFDFDLDA
                     SAFLTGTDGKVTNDGDFIFYNNLKHASGAVEYMGDNRTGVGDGDDEQINVDLSKIPQN
                     IAKISFSVTINEAITRRQNFGQVENSYIRIYNEETNEELIKYELGEDFSIETAIVVAE
                     LYRHNGEWKFNALGSGFEDGLAGLCKNFGVNIG"
     gene            complement(5576..6493)
                     /locus_tag="PC494_003223"
     CDS             complement(5576..6493)
                     /locus_tag="PC494_003223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDF3913697.1"
                     /translation="MTIRSLEIFVKVAECGKMSEVARNMYITQSSVSQAISEIEKEYG
                     VKLFDRISKKLYLTEAGKKLLGYGRHLLAVNEEMNDCMKHCAKNIRIRVGATVTVGTC
                     VISPIMLELYKVNPLIEPEVFVEDTRLIAKKLLNSELDIAIVEGKIKHPDIVTKSIIN
                     DNLVLICSHKHEFYKRDSIKVSELSNQPLIMRELGSGTRAQLEKQLKELKIPMNIRWS
                     CYNSEAILRAVVDNFGIAVISELLIEDYLKKHLLWACDIEGINLHRTFDIAYHRSKFF
                     TENISAFFDISVEYGKKQARKKSRSVNSL"
     gene            6623..8254
                     /locus_tag="PC494_003224"
     CDS             6623..8254
                     /locus_tag="PC494_003224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HDF3913698.1"
                     /translation="MKVLIIGGVAAGTKTAAKIKREMGDNCSVTILNKGDDISYAGCG
                     LPYYVGKIIEDKSSLIVNTPESFSKLTGAEVRCGVEVTSIDRNAKQVTLKTLSTGEKE
                     NLSYDKLVIATGADPIKPPIPGIDLPGVFFMRTPNDAIKLRDSIENGIKRAVVIGGGF
                     IGLEIAENLSAMGIRVSVVDMAEHVMPGFDTDFAEYVENHMADKGIMIFTGDQVVGIE
                     GENKVEKLRTKNRAIKTDLVVMSVGIRPNTGFLKDTGLEFAPNNTIIADEYMLTNDKD
                     IYVVGDCAFVKNSLTNKPTWSPMGSSANHEGRICAQNISGKSKTYNGVLGTTVVKLPE
                     LNAGKTGLSKEIAEKEGYNVCSVTIATDDKAHYYPGASNFIIRMVAEKNTRKLLGVQV
                     MGPGAVDKIVDIAATAITLGADLYSLESMDLAYAPPFSTAIHPFVVAVNVLQNKLNGE
                     LDSVLLDEIEDFDSWTKLDVSKAPSIPSLRYIPVGEINGEIEGLAKDEKILLICAKGK
                     NSYMAQNRLRRFGYTNTKVLEGGILFYPNLKVMEE"
     gene            8257..9204
                     /locus_tag="PC494_003225"
     CDS             8257..9204
                     /locus_tag="PC494_003225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013378669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(4Fe-4S)-binding protein"
                     /protein_id="HDF3913699.1"
                     /translation="MSNVTAEQKKEVKGRGFLPSRDGEHFAARIITVNGVINASQAKK
                     IAEAAEKFGNGQLAFTTRLTVELPGVKFEDIEALSEFIASENLITGGTGSRVRPVVAC
                     KGTVCVHGLADTQALAAEIHEEFYKNWYDVKLPHKFKIGVGGCPNNCIKPDLNDLGIV
                     GQRVPDYDSELCVGCKKCAVVEVCPVKAAKLTDKGKLEIDSNLCNNCGKCIESCNFDS
                     IEEKESGYKVYIGGKWGKSVRPGTQIDRLFSKEELMTLIEKAILLFREQGNTGERFGI
                     TIDRIGADKFIEMLLSDEVLERKEEILEALLHLTGGAVC"
     gene            complement(9489..9752)
                     /locus_tag="PC494_003226"
     CDS             complement(9489..9752)
                     /locus_tag="PC494_003226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1883 domain-containing protein"
                     /protein_id="HDF3913700.1"
                     /translation="MEYSYSKMNLKKGDIVEVNLEKQANVILLDHINYVKFKNQRNYD
                     YYGGFAKKNPCRMRVPNTGTWYLVVNQDGNSGIVNFSINTIQN"
     gene            complement(9851..10096)
                     /locus_tag="PC494_003227"
     CDS             complement(9851..10096)
                     /locus_tag="PC494_003227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3913701.1"
                     /translation="MFIDEELEGYILTCKISEDFKNIPEYSDEEFYVTVYKDESSDSG
                     YYALLENKEERVVWDGEVVANNIFNNLWIVINKVKTG"
BASE COUNT         3540 a         1461 c         1422 g         3724 t
ORIGIN      
        1 gtttttattc tccaattgat atattattta tgccattatt tttaacttca ataattggtt
       61 gtccatttcc taaaatataa tctttagacc aaccttctgg caatttattt atcccatttc
      121 caattaactt caagtgtaaa tttgatggtt cttttttcag atttaattta aatattccat
      181 caaaagtatc tttattatcg cttccaaata aacttatatt gccatttata tttgtagctg
      241 ttacatttac aattccattg tttgctctaa attttatttc agatgatata gtttcagctg
      301 ttacacctga aatcccacta ttagtattta tattgaaagg atttgttaca ttgttatcaa
      361 caatgttagc aattccgtca ttgacatcaa cagtagctcc tcctttaata ttataaagtt
      421 ctactgaacc actttcaaca tctactttaa aattagaata cattttatcg ggaactccaa
      481 tttttatcac atttaccatc ctatctttat ttgcatttat catattgtcg ccattcatat
      541 cttgcaaatc actatctttc ttatctattt ttttcttagc acttacaact agctttccat
      601 tttttatatt attagaagaa ttttctttat atacagaaaa agtacaattt ttttcattag
      661 ttacacttac gtaatcaaac tcaaatttat tggtattcgt cttttcaaca accacaccta
      721 aattatctga ttctataagt atttcagaaa cttcatttcc ttcaactgaa gttaagtgtt
      781 ttaaaatatt tggagtcata tccatattat tatatttaat catatctaaa cactgtttat
      841 atatattggc atcaatacct ccaacttttg ttatactttt agctcctttt aaaatacctt
      901 tattacttcc atcagcaact aaaacgattg gtttttcttt ggctaaagga gataatgtta
      961 gtgcatctac taattgatat ccatttgtta tataaaaatc tgtagctcca ttataaaact
     1021 tttccattac ctttttattg gtctcaaatc tatcatttcc tccgattcta attgctttag
     1081 tttcatttac taaatcctca tttatcgcag atttgccacc tatagcgtaa acatttaaac
     1141 cttcagtctt aaatggaact gatttcccat ctgtaagtat tatagctcct ttattttttg
     1201 caactacagg tgctatactc atagcatcag cctctcctac aaatccattt gtaagcatta
     1261 cctcttttac actacttact tcatttattt ttttagctac attataacta gtttcaattc
     1321 tattgttacc atttattctt tccacttgaa taccttttct ttttatatct ttttctactg
     1381 aattttcaat agtattataa ccaccaatta tatatacttt ttttacaaca tttaaactct
     1441 tattatctag tctatttaaa gtagcttttg gtatttcact ttttttagtc aaaagtattg
     1501 gtgcgttaat agctccagct aatccacttg atgaaagccc atcagataaa tttttatctc
     1561 cattaactaa tattacagta tcataagttt gtctatccgc tataagtcct gctgtttcat
     1621 atctatcaat tcctattatt gaatcttctt taatctgtgc atttgcagtt aaattattaa
     1681 aaagaaacat agtcaaaact aaaattaata tacttagttt tttactgaat tttttgaatt
     1741 ttttattcat aatatacact attcctcctg taaattaagg tctttaattt gcttataaat
     1801 tatcccctta tttacaaata ataacataat attatagtaa cgtatatatt accttaaaat
     1861 tatcagtaac tttatatcaa tcatcttagc ttatttatat aaattttttt atattacttt
     1921 tcaaataaca gtcatactaa aacaatttca tcatataatt tgaaaattat tactatttac
     1981 gcagctttta tcatcatctt accaccatca aatatatatt caaccatatt attctcatat
     2041 aaataagtta tataagaacg tattgtactt ccaaccaaca catattgatt agcatcaagc
     2101 ttgacattgt acaaatcaca cattttttca ataacttcat caatcataac tggctcataa
     2161 caaacctttt taatattatc tattatttct tccatcttct tcttattaat attaattaaa
     2221 ctttttatat ctgtagtttt gacagagtga cttggaacaa agaaatcagc ctctaacatt
     2281 ctcaattttt ctagtgtctt aaactgtgaa tctatatcca gtaggaagaa aaaatgatat
     2341 ttagtaatta tattctctgg tgtaagacta tctgcaacaa acaaaacatt atctggagtt
     2401 ctaacaccaa tcatttcaaa ataatgacct ggaagagaaa tcgcttcaag ttctgtatct
     2461 acaattttgc catttgaagg tataatataa tcaacttcac tttcctttgc taataaaaat
     2521 ttattcttca gtgctttact tggatagcca ccatataaaa atgctgattc taatattgga
     2581 ttttctgtaa aatatccttc aattttagtc gtagcaatct tgcattttgt ttgattcttc
     2641 aaatatgcat ttcctcctat atggtctgca tttgaatgag tgtttattat taatttagga
     2701 tttaaattat gttcttctaa taatcttaaa acttgtctag ctgtatcctt attatttcca
     2761 ctgtcaatta aaattgcatc cttaccatct acgtatacac ctactattgt agggagtgga
     2821 atataatatg tatttccttt tatatgttct agagttaatt tagccatttt ataacctccc
     2881 tttaaattta cttttaatta tagcattaat tttctgaaaa ttccaatcaa attgttttta
     2941 taatatattt ttatttcttt tattaaaaat tggaaaaact atataatata tattataatc
     3001 tatatataag gagtgatgtt attgaaaaaa gatagaataa ctttttcaga aattttaata
     3061 ttaattgtag gctgtatatt aatggccatt tctcttaact tattttttaa tccacatgca
     3121 atcgctgctg gtggtataac aggacttgga gttgttttaa attcattatt cggtgtagaa
     3181 ctttggattg tcaatttact tttaaatgtt ccattattca tatttgctta caaaatactt
     3241 tcaaaaaaag attgttttaa aacggtttta ggaataattt ttcttaccat agcacttaag
     3301 cttactgcaa atatggctac attagatata acaaatgata tgtatcttgc aattatatct
     3361 ggttctattt taatgggagt tggtcaagga cttattttta gaataaatgg ctctacaggt
     3421 ggaactgatt taatggcact cctactaaat aaatattttc ctacatttag tatacctgtt
     3481 ttaatgggta ttgtagactg cgttgtagtt gttttatcag gtatagtaaa tagacaggtt
     3541 gaaattgcac tttattcaac tgtggcttta tacattttag taaaagttag tgacttgctt
     3601 attgaaggat ttaattattc caaatcattc actattatat ctgacctttc aaaagatata
     3661 agtaaaaaaa taatggaaga tttagataga ggtgcaacta ttctaaaagg agaaggtgca
     3721 tatactggag aaaataaaaa tgtactttta gtagtagttg aaaagaaaga agttgtcgaa
     3781 ttgaaaaaat tagtaaaaaa tgtcgaccct aatgctttta ttataattac agatatacat
     3841 gaagctttag gtaatggatt taaaaaaata gaataactaa caaataaata gcaagtataa
     3901 ttaacatata caaattcaac tttttatatg ttatattata cttgctattt atatattata
     3961 cttgctattt atatattata attgttgttt ttaagataaa aattaaatgt atcaattatt
     4021 gttttataca agtatttcca aatccgttct catttagata gtatgcttag aaattttaga
     4081 attattgagt ctaactttat tacttacttt actttataac aatcaaatac aaatttaaat
     4141 attataaaac tacaaaataa tttaaagcat ataatgtcaa tatgtttaaa ttataaaata
     4201 ttcatgtagt tatataataa ataatttata aatatagcca acttagccta aatacgtata
     4261 taatatagct aatatggttc ttatacttga taccatcaat aaaactaaaa atataaaaag
     4321 gagaacttaa aatgagtgtt agtttacaaa aaggacaaag agttagctta gtaaaagata
     4381 ataatcctgt aaaaaatcta gtagtaggct taggatggga tatgaataaa ttgggtaaaa
     4441 aaaattatga cctagatgca tttgcaatag cattgactaa ccaagataaa atgaatgtta
     4501 gaggtgactt ggtttatttt ggaaatctta aacacccttc taaagctatt atacacactg
     4561 gagataactt aactggaaaa ggtgaaggtg atgatgaaca aataattgtt aatttagaag
     4621 acatacctga atatgtacat aaaatagttt ttggagtttc tatatacaaa gctaaaaaaa
     4681 gagaccagga ttttggtcaa atgaacaact cttttataag attaattgat tcaaattcca
     4741 agcaagaatt atttaaatat aatcttcaag aagacttttc tggtaaagta acagttttgg
     4801 caggagaaat ttatcgtaga aatgaagaat ggaaatttaa tgctttagga attggtcaaa
     4861 atgaagagct tcgtgaatta attaatacat ataagtaata attacaataa aaaatttata
     4921 atgaggagtt ggtttaaatg ggtataactt tagcaaaagg acaaaaagta agtttaacaa
     4981 aaagtaaccc tggtctaaaa aaagtaatag taggactagg atgggatatt aataaatatg
     5041 atggtggctt tgatttcgat ttagatgcct ctgcattttt aactggaact gatggaaaag
     5101 taacgaatga tggagacttt atattctata ataatttaaa acacgcttct ggagctgttg
     5161 aatatatggg tgataataga acaggtgttg gtgatggtga tgatgaacaa ataaatgtag
     5221 acttatctaa aatacctcaa aatattgcta aaatatcatt tagtgttact ataaacgaag
     5281 caattacaag aagacaaaat ttcggacaag ttgaaaattc atatataaga atatataatg
     5341 aagaaactaa tgaggaactt attaaatatg aattgggtga agattttagc atagaaacag
     5401 caatagttgt ggcagaacta tatagacata atggagaatg gaaatttaat gctttaggtt
     5461 ctggatttga ggatggactt gcaggattgt gtaaaaattt tggcgttaat ataggctaat
     5521 atatctaaat aaaaataaga gtatattgat atactcttat ttttatttag atatattata
     5581 aactgtttac acttctactc ttctttctcg cttgtttttt cccatattct actgaaatat
     5641 caaaaaatgc tgaaatattt tctgtaaaaa acttgcttct atgatatgca atatcaaatg
     5701 tcctatgtaa attaatacct tcaatatcac aagcccacaa aagatgcttt tttaaataat
     5761 cctcaataag taattcggat ataactgcaa tgccaaaatt atctacaact gctcttaata
     5821 tagcttcaga gttataacat gaccatctaa tattcattgg gatttttaat tcttttaatt
     5881 gcttttctaa ttgtgctctt gtaccacttc ctaattcacg cataattaat ggttgatttg
     5941 aaagttctga aacttttata gagtctcttt tataaaactc atgcttgtgt gaacatataa
     6001 gtacaagatt atcattaata atgctttttg taacaatatc tgggtgctta atttttcctt
     6061 ctacaatcgc aatatctaat tcactattaa gtaatttttt tgcaatcagt cttgtatctt
     6121 ctacaaatac ttcaggttct ataagaggat ttaccttgta taattctaac attattggac
     6181 ttattacaca tgtaccaaca gttactgttg ccccaactct tatacggata ttttttgcac
     6241 aatgcttcat acaatcattc atttcttcat ttacagctaa aagatgcctc ccatatccaa
     6301 gaagtttttt ccctgcctca gttaaatata atttttttga aattctatca aatagcttaa
     6361 caccatactc tttttctatt tctgaaatag cttggctaac tgatgactgg gtaatataca
     6421 tatttcttgc tacttcactc attttaccac attcagcaac cttaacaaag atttcaagac
     6481 tacgaattgt catattatca caaccttagc aaacattagt aaatgcttat gattttatta
     6541 atattttagt attttacaaa tatattgtca agaagtataa ttttattata gagttataaa
     6601 gtagattgga gtgtgatata ttgtgaaagt attaattata ggtggagttg ctgctggaac
     6661 aaaaactgct gcaaaaataa aacgtgaaat gggtgataat tgctctgtta caatactaaa
     6721 taaaggtgat gatatttctt atgcaggttg tggtcttcca tattacgttg gtaagataat
     6781 tgaagataaa tcatctttaa tcgtaaatac acctgaaagt ttttctaaac taacaggagc
     6841 agaagttcgt tgtggagttg aagttacatc tattgataga aatgcaaaac aagtaacttt
     6901 gaaaacgctt tcaacaggag aaaaagaaaa tctaagctat gacaaacttg taattgctac
     6961 aggggcagac ccaataaaac caccaatacc tggaatagat ttacctggag tattctttat
     7021 gcgtactcca aatgatgcta taaaactaag agattctatt gaaaacggta ttaagagagc
     7081 tgttgttatt ggtggaggtt tcattggtct tgaaattgct gaaaatcttt ctgcaatggg
     7141 tatacgtgta agtgttgttg atatggctga acatgttatg cctggatttg atactgattt
     7201 tgctgaatac gttgaaaatc atatggctga taaaggcata atgattttta caggtgacca
     7261 ggttgtaggt atcgaaggtg aaaataaagt tgaaaaactt cgtactaaaa atagagctat
     7321 taaaacagat ttagtggtta tgtcagttgg aatccgtcct aacacaggtt ttctaaaaga
     7381 cacaggttta gaatttgccc ctaataatac aattattgca gatgaatata tgcttacaaa
     7441 tgacaaagat atatacgtag ttggagactg tgcttttgta aaaaattctt taacaaataa
     7501 acctacatgg tcacctatgg ggtcatctgc aaatcatgag ggtagaattt gcgcacaaaa
     7561 tatatctgga aaatctaaaa cttacaatgg tgttcttgga acaacagtag taaaattacc
     7621 tgagctcaat gcaggaaaaa caggtctaag taaagaaata gctgaaaaag aaggttataa
     7681 tgtttgctct gtaaccatag ctactgatga taaagctcat tattatccag gtgcatctaa
     7741 ttttattata agaatggttg ctgaaaaaaa tactagaaaa ttattaggtg ttcaagttat
     7801 gggacctgga gcggttgata aaatagtaga tatcgctgct actgcaataa ctttaggcgc
     7861 tgacctttat tcattagaaa gtatggacct tgcatatgca ccaccttttt caacagctat
     7921 tcaccctttt gtagtggcag taaatgtttt acaaaataaa cttaatggag aacttgatag
     7981 tgttttactt gacgaaattg aggattttga cagttggact aaacttgatg tttcaaaagc
     8041 tccttctatt cctagtttac gttatattcc tgttggtgaa attaatggag aaattgaagg
     8101 ccttgctaag gatgaaaaaa ttcttcttat atgtgctaaa ggtaaaaata gctatatggc
     8161 gcaaaatcgc ttaagacgct ttggctatac aaatacgaaa gttcttgaag gtggaatact
     8221 attttatcca aatcttaagg taatggagga gtaaatatga gtaatgttac agcagaacaa
     8281 aaaaaggaag taaaaggtag aggttttcta ccaagcaggg atggagaaca ttttgcagca
     8341 cgtataataa ctgtaaatgg tgtaataaat gcatcacaag caaaaaaaat tgcagaagct
     8401 gctgaaaaat tcggaaacgg tcagttagca tttactacta gactaacagt agaattacct
     8461 ggtgtaaaat ttgaagatat tgaagctcta agtgaattta ttgctagcga aaatctaata
     8521 acaggtggaa ctggatcaag ggttcgtcct gttgtggctt gtaaaggtac tgtttgtgtt
     8581 catggtctag ctgatacaca ggcacttgct gctgaaatac acgaagaatt ttacaaaaat
     8641 tggtatgatg taaaactacc tcataagttc aaaattggtg ttggtggatg ccctaataac
     8701 tgtattaaac ctgacctaaa cgatcttgga attgttggtc aacgtgtacc tgactatgat
     8761 tcagagcttt gtgttggttg taaaaaatgt gctgttgtag aggtctgtcc tgttaaagca
     8821 gctaaattaa cagataaagg taaacttgaa atagatagta atctatgtaa taactgtggt
     8881 aagtgtatag aaagttgtaa ttttgatagt attgaagaaa aagaatctgg ttataaagtc
     8941 tatataggag ggaaatgggg aaaatcagtt cgtcctggaa cacagattga tagattattt
     9001 tcaaaagagg aacttatgac tttaattgaa aaagcaattc ttttatttag agaacagggt
     9061 aacacaggtg aacgttttgg aataactatc gatagaatcg gtgctgataa atttatagaa
     9121 atgcttttat cagatgaagt tttggaaaga aaagaagaga tactagaggc tcttttacac
     9181 cttacaggtg gagctgtatg ctaacaataa atattttaat tgtacagata acctatggaa
     9241 aaaattttag ttaagaataa ttaaaattct atatatgata tatgataaat gaggctatct
     9301 caaaacacag atacgcctct ttttcattgt tgaaatgata aagtatattt gagttcatat
     9361 aaaaaagagt gtctcgtgaa ttataaaatt cattttgagg cacccacatt attttataat
     9421 aattgcttat taattttatt ttaactatat aaaaagtaca aaaagtaaga atatccaata
     9481 ttctaaaatt aattttgaat tgtattgatt gaaaagttta ctattccact atttccatct
     9541 tgatttacta ctagatacca tgttccagta ttaggaactc tcattctaca tggatttttc
     9601 tttgcaaatc caccatagta atcataattt ctttgatttt taaatttcac ataatttata
     9661 tggtctaaca atattacatt ggcttgtttc tctaaattta cctctacaat atcccctttt
     9721 tttaagttca tcttactata actatattcc attgaattac tcctccagta tcgaataatc
     9781 tttgttattt actcatctca aatatgtaaa aattcattta aaatattaca aatactatat
     9841 aattagacta ttatccagtt ttaaccttat ttattacaat ccaaaggtta ttaaaaatat
     9901 tattggcaac aacttctcca tcccatacaa ctctttcttc tttattttct aataaagcat
     9961 agtacccaga gtcagaactt tcatctttat agactgtaac ataaaactct tcatcactat
    10021 attcaggtat atttttaaag tcttcagata ttttacatgt taatatataa ccttctaatt
    10081 cttcatctat aaacaaagca attcctccaa tctctatatt tttactaatt ataccatatt
    10141 atgtcat
//
LOCUS       DAMKNB010000109        10078 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.115, whole genome shotgun sequence.
ACCESSION   DAMKNB010000109 DAMKNB010000000
VERSION     DAMKNB010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 10078)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10078)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10078
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.115"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            complement(9..143)
                     /locus_tag="PC494_003228"
     CDS             complement(9..143)
                     /locus_tag="PC494_003228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017143882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3789 domain-containing protein"
                     /protein_id="HDF3913702.1"
                     /translation="MWELLKDFLLVSLGMGIGVVLMCILTVGKEADRCMEEIKEREEH
                     "
     gene            complement(150..1349)
                     /locus_tag="PC494_003229"
     CDS             complement(150..1349)
                     /locus_tag="PC494_003229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HDF3913703.1"
                     /translation="MNETDFLTALKAKRCAYSVSQTRLAIMANISREHLSRIEAGKVT
                     LTEDMKHTLLEAVEKFNPDNPMFLLFDYVRIRFPTMDIKHIIKNILKLNIDYMLHEDY
                     GHYKYTEHYHIGDVFVYVSQDEEKGVLLELKGKGCRQFESYLLAQERNWYDFFTDALV
                     EGGVMKRLDLAINDRTGLLDIPELIQKCENEECISKFRSFKSYGSGELVKHNETDKYG
                     MGHTLYIGSFSSEVYFCCYEKNYEQYAKLGIPIEEVPIKNRFEIRLKNERAYYAVVEL
                     LTHYDAEQTAFSIINQYIRFADKEPDKRKSDWKTNVRWAWFIGEGRPPVKLTTKPKPY
                     TLERTLNWLQRQVAPTLKMLKQIDKDNQTEYLETIEKQAKLTERHHQIIKQQTATVEE
                     MVAKVKE"
     gene            complement(1551..2945)
                     /locus_tag="PC494_003230"
     CDS             complement(1551..2945)
                     /locus_tag="PC494_003230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008787614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HDF3913704.1"
                     /translation="MRIIWNKGHRIRASDKNLVYRFSLGTLLIVFVVVLLLLNMKQLM
                     RTDWEHFSLLDNSFTLSLYNFITLLIATGVCALVAFLYYRFCYDNFKKLLHRQKLARM
                     ILENKWYEADTVQDSGFFTDLQSRSREKIVWFPKIYYQMEKGLLHIRCEITLGKYQDQ
                     LLRLEDKLESGLYCELTDKTLHDGYIKYILLYDMIANRITIDEVRAENGCLRLMKNLV
                     WEYDALPHALIAGGTGGGKTYFLLTLIEALLHTNAVLYILDPKNADLADLGTVMGNVY
                     HTKEEMIDCVNAFYEGMVQRSEEMKQHPNYKTGENYAYLSLPPCFLIFDEYVAFFEML
                     GTKESVSLLSQLKKIVMLGRQAGYFLIVACQRPDAKYFSDGIRDNFNFRVGLGRISEL
                     GYGMLFGSDVKKQFFQKRIKGRGYCDVGTSIISEFYTPLVPKGYDFLQTIGSLAYARQ
                     DGTATCEAKGDGTD"
     gene            complement(3056..3367)
                     /locus_tag="PC494_003231"
                     /pseudo
     CDS             complement(3056..3367)
                     /locus_tag="PC494_003231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896960.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YcxB family protein"
     gene            complement(3395..3937)
                     /locus_tag="PC494_003232"
     CDS             complement(3395..3937)
                     /locus_tag="PC494_003232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3795 domain-containing protein"
                     /protein_id="HDF3913705.1"
                     /translation="MKGFERKNQLFSLCGLNCGLCPMLLGNYCGGCGNGNQSCRIAKC
                     SLEHGQIEYCYECKQYPCEKYQHIDDYDSFITHKQRKADLERAKNIGIEQYNLEQQEK
                     TQILSYLLSNYNDGRRKTFFCVAVNLLELSELQEAMKQIQSNDELTLLPFKAQCLYVV
                     EVFQKIAERRNIKLKLFKKK"
     gene            complement(3998..4600)
                     /locus_tag="PC494_003233"
     CDS             complement(3998..4600)
                     /locus_tag="PC494_003233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDF3913706.1"
                     /translation="MDKVVIYIHGKGGNAEESSHYKPLFSDCDVVGLNYTAQYPWEAK
                     EEFPSLFDLICKHYKSVQIVANSIGAYFAMNALSDKQIEKAYFISPIVNMEKLIADMM
                     YWANVTEDELRDKKEIKTTFGETLSWEYLCYVKENPTTWKIPTNILFGEKDNLTSYAT
                     ISEFTKQTNATLTVMRNGEHWFHTEEQMKFLDEWINKSAR"
     gene            complement(4655..5068)
                     /locus_tag="PC494_003234"
     CDS             complement(4655..5068)
                     /locus_tag="PC494_003234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3788 domain-containing protein"
                     /protein_id="HDF3913707.1"
                     /translation="MLDKIPNAEEMTALVGQSLYAIWNKLCALIDEKYDMECLWNKGG
                     KAWTYEYKYRRGGKTLCALYARENCVGFMIILGKDERLKFDTDRNSYSKEVQKIYDET
                     KTYHDGKWLMFEPTDTILFNDFVKLLGIKRKPNRK"
     gene            complement(5132..5590)
                     /locus_tag="PC494_003235"
     CDS             complement(5132..5590)
                     /locus_tag="PC494_003235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HDF3913708.1"
                     /translation="MKFKNPMLVVTDIDKSVEFYKKVFGLRVIMDFGANKTLTGGLAL
                     QTSETYKEFIGTSDISFGGKNFEVYFEEDDFDKFADRLKEYDIEYVHPIIEHSWGQRV
                     VRFYDPDKHIIEVGENMKIVCKRFLNSGMTPEQVAERMDVPMKFINACMR"
     gene            complement(5671..6084)
                     /locus_tag="PC494_003236"
     CDS             complement(5671..6084)
                     /locus_tag="PC494_003236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HDF3913709.1"
                     /translation="MRLANGIVLDNEKTFGVLKFSALRHEVRVENEDGTTSDEIKRRT
                     YDLKCSVQERMIQVSIPADVPVKDFPYNAEVELINPVADTVANANFRGADVDWYIKAD
                     DIILKNKGNQPAGNPQNNNPQNLAPQGQQKNKLAN"
     gene            complement(6099..6422)
                     /locus_tag="PC494_003237"
     CDS             complement(6099..6422)
                     /locus_tag="PC494_003237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014080830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HDF3913710.1"
                     /translation="MELKYIVPNVAQTFGNLEFAGENKVDQQHINGRYTPVSRSYNLY
                     SDIQRADDIIVVLPAKAGEKHFKPEQKVKLINPRITAEGYNVKGRGFTNYILMADDML
                     PAESK"
     gene            complement(6644..9691)
                     /locus_tag="PC494_003238"
     CDS             complement(6644..9691)
                     /locus_tag="PC494_003238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SrtB-anchored collagen-binding adhesin"
                     /protein_id="HDF3913711.1"
                     /translation="MKKILKRLCTGFLAFATVVTALPSSTVHASNTQYWTESKERVGI
                     VEQVMNDGSISSTFNEGHLTVEGKDAYCIDINTAFKNGYKTRTDASSRMSADRISDVA
                     LSIEYVKQYTDSHSGISSKHAYLLKQLVVWQRLSVQLDWQCDNVRASYDEIPKAVQDE
                     VFAGAKAFVKENKGRYDCGGYIYSGEGQELGQFWAKLAVGNAKLQKTSTNANITDGNG
                     IYSIAGATYGVYSDKDCTKQLATLTTDTSGNTEAVEVRATTVYIKELSAPAGFKIDKT
                     VYSLSVEAGKTATLKVSDTPKVTDTLIELFKIDMETQKSNSQGNASLEGAEFTWNFYA
                     GYYNKNNLPAQPTRTWVTKTIAEKDSDGAIHYITRLANAYKVSGDSFYMQDGKNVLPL
                     GTLTVEETKSPSGYLLEGAYMQADGSEEQIKEMYLTQITEDGDLAVLSGSNQYHVSDK
                     VIRGGVKIQKRDLETKDTKAQGGATLKNTAFEIISLNENAVLVESKLYKKNEVLKTIH
                     TDIEGIASTSADLLPYGKYRLSEQKPPEGYLTDGAKPIDFEITENGKIVDLTDEAHSI
                     YNQIKRGDIEGVKIGAGSHKRLADVPFRITSKTTGESHVVVTDDNGQFSTASDWASHK
                     HNTNAGKTSEDGVWFGTSEPDDSKGALIYDTYIIEELRCESNKGFKLIPPFEIVISRN
                     KVVVDLGTLTDEYEKEITIHTTATSKDGEKTILAGNDVTIIDTVKLDGLVKGTKYQLK
                     GWQMLKKENAELLVGDKRVESDYTFVADDEAMKVEIAYTFNASALGGKNLVTFEELYD
                     LSNPEEPVKVAEHKDIEDDGQTVLITERIIKIHTTATDKDGKKEIEAGKDVTIVDTVK
                     LEGLEVGTKYQLVGWQMLKEENAELIINDKKVENDYTFTSDSETMEVKIAFTFDASSL
                     GGKQFVTFEELYDLSNPDKPIKVTEHKDIEDDGQTVTIKEVPETPTPEEPEKPTTPDT
                     PTKTDSPKTGDNTNILAFAIMMFVSAGGLAGTYFFKRRKMKKS"
BASE COUNT         2668 a         2162 c         1763 g         3485 t
ORIGIN      
        1 aaattcattt aatgttcctc tctttctttg atttcttcca tacatctgtc agcttctttg
       61 ccgacagtta aaatgcacat caagactacg ccgataccca ttcccagaga taccagcagg
      121 aagtctttca ataattccca catttttcat cactccttta ctttggcaac catttcttca
      181 accgtggctg tctgttgctt gattatctgg tggtgtcgct cggtcagttt tgcctgcttc
      241 tcaatcgttt ccagatactc cgtctgattg tccttgtcta tctgtttcaa catcttcaag
      301 gtcggtgcaa cctgcctttg tagccagttg agtgtacgtt ctaacgtgta cggttttggc
      361 tttgttgtca gctttacggg tggtcgcccc tcgccaatga accaagccca gcgtacattt
      421 gttttccagt cgctttttcg cttgtctggt tctttatcag caaagcggat atactggttg
      481 ataatagaaa atgctgtctg ttctgcgtca taatgtgtca gcagttccac aacagcataa
      541 taggcacgtt catttttcaa acgtatctca aatctatttt ttatggggac ttcttcaatc
      601 ggtatgccaa gttttgcgta ctgttcgtaa ttcttttcat aacagcagaa gtatacttca
      661 cttgaaaatg aaccgatata caacgtgtgt cccataccgt atttatccgt ttcgttatgc
      721 tttaccagtt ccccagaacc atagcttttg aaagaacgga atttagaaat acattcctca
      781 ttctcgcatt tttgtatcag ctctggaata tcaagtaaac ccgttcggtc attgattgcc
      841 aaatcaagac gtttcatcac accgccctca accaatgcgt ccgtgaagaa gtcataccaa
      901 tttcgctctt gtgccagcag ataactttca aactgacgac agcctttgcc tttgagttct
      961 agcaggacac ctttttcctc gtcctgcgat acatacacaa acacatctcc gatatgataa
     1021 tgctcggtgt atttataatg tccgtaatct tcgtgaagca tatagtcgat attgagcttt
     1081 aatatattct tgatgatatg ctttatatcc attgtgggaa aacggatacg cacataatca
     1141 aacagcagga acatgggatt gtcgggattg aatttttcca ccgcttctaa aagcgtatgt
     1201 ttcatgtcct cagtcagcgt tacctttcct gcttcgatac ggctcaaatg ttcacggctg
     1261 atatttgcca tgattgcaag ccttgtctgc gatacgctgt atgcacagcg tttcgctttc
     1321 aaggcggtta aaaaatcagt ttcattcagt tgtcataccc ccaatcgtga taattttgtg
     1381 atattgtgat aatttcaagg ttttatcaca aaaggcgaga tgtacgaaaa accctcattc
     1441 catgcggtct tgcaaaggtt tttgtggaag tttccgccgt aattgtgccc ctctgttaga
     1501 taatgagggg cttgtttctg ctggtgtggc gttagccaca ccagcaacgg ctagtccgtg
     1561 ccgtcgcctt tcgcttcgca cgtcgccgtc ccgtcctgcc ttgcatatgc aagagaacct
     1621 atggtctgca aaaaatcata tcctttcggg actaaaggcg tgtaaaattc acttatgatg
     1681 cttgttccca catcacaata gccacgccct ttgatacgct tctggaaaaa ctgttttttc
     1741 acatcagaac caaacagcat accgtaacct aattcgctga tacgtcccaa ccctacacgg
     1801 aaattgaagt tatctctgat accgtccgag aaatattttg cgtctggtcg ctggcaggca
     1861 acgataagga aataccctgc ttgtctcccc agcatgacga ttttctttaa ctggctaagt
     1921 aaactcacgc tttcctttgt ccccagcatt tcaaaaaacg ccacatattc atcaaagatt
     1981 aaaaagcagg gcggtaagct aagataggcg tagttttctc ctgttttata gttcgggtgt
     2041 tgcttcattt cttcgcttcg ttgtaccatg ccctcataaa aggcattgac gcaatcaatc
     2101 atttcttctt tagtgtgata cacgtttccc atgactgttc ccaaatctgc aaggtcagcg
     2161 ttctttgggt ctaagatgta aaggacagcg ttggtatgca gtagggcttc aatgagcgtc
     2221 agaagaaaat aggttttacc gccaccagtc ccaccagcaa tcagagcgtg agggagtgcg
     2281 tcatattccc agacaagatt tttcatcagt ctaagacagc cgttttctgc ccgtacttca
     2341 tcaatagtaa tgcggtttgc tatcatgtca taaagcagga tatatttaat atagccgtca
     2401 tgtaaggtct tgtcggtcag ctcgcaatac aagccacttt ccaatttatc ctctaaccgt
     2461 aaaagttggt cttgatattt tcctaatgtg atttcacagc ggatatgaag cagtcccttt
     2521 tccatttgat aataaatctt tggaaaccag acgatttttt cccttgatct gctttgcagg
     2581 tcagtaaaaa aaccgctgtc ttgtacggta tcggcttcat accacttatt ttccagtatc
     2641 attcgtgcca gcttttgacg gtgcagtagc tttttaaaat tgtcataaca aaagcggtaa
     2701 tacagaaaag cgaccaatgc acaaacacca gtcgctatca gtaaggttat gaagttgtat
     2761 aaggaaagcg taaagctgtt gtctaataag ctgaaatgtt cccagtcggt acgcatgagc
     2821 tgtttcatat tcagtagcag aagaaccacc acgaatacaa ttagaagcgt tcccaatgaa
     2881 aagcgataga cgaggttctt atcgctggct ctgatacggt gtcctttatt ccaaattatt
     2941 cgcataaatc aatcactcca atcttaaatt taagtatgaa aaaagcagtc aatcttaaaa
     3001 gactaaccgc tttgtgtgta tgaatatgaa gttgttacat tgtagggtat gttcattata
     3061 tatgctttgt tgttttaact cttgattgtg caatttcttc aaatagctgt ttttcgttta
     3121 ggtctttaaa aactcttttg ggaattaacg tatataatcg tggtgcttga attaagtaat
     3181 aaaaatcatg gctttcccat agtgcagagt aaatgtccca cttcacttct gagtcaatgc
     3241 tttgtgtttt aaatttaatg ttttccttag aaaataccag cgtatattcc tcatgatatt
     3301 ttgcagtttg tttgaatttc agtataggca ttaggatata taaatagctt cccaatgcag
     3361 ttacaactct ttgctacaat ttcaaatttg aaaatcactt tttcttgaaa agtttcagtt
     3421 ttatatttct cctttcagca atcttctgaa acacctccac cacatacaag cattgtgcct
     3481 taaatggtag taaggtcaat tcgtcattgg attgtatttg tttcattgct tcttgtaatt
     3541 ctgaaagttc taataaattg actgccacac aaaagaaagt ctttctacgc ccgtcattat
     3601 agttagaaag taagtaagaa agaatttgtg ttttttcctg ctgttcaaga ttatattgct
     3661 caatgcctat gttttttgct ctttctaaat ctgcttttcg ctgtttatgc gtgatgaaag
     3721 aatcataatc atcaatgtgt tgatattttt cgcatggata ttgtttgcat tcatagcaat
     3781 attcaatctg tccatgttca agactacatt ttgcaattct gcatgattga ttaccattgc
     3841 cacaaccgcc acagtaattt cccaaaagca tagggcatag tccgcaattc aatccgcaaa
     3901 gagaaaataa ttggtttttt cgttcaaatc ctttcatagt accagtctcc taacttcaaa
     3961 tttatctttg tatttattga cttttacaaa ctgggattta tctggcagac ttgtttatcc
     4021 actcatcaag aaatttcatt tgttcttccg tgtgaaacca atgctctccg tttctcataa
     4081 cagtaagtgt tgcattagtt tgttttgtaa attcagatat agttgcataa gaagtcaagt
     4141 tatctttctc accaaataaa atatttgttg gaattttcca tgtagttgga ttttctttta
     4201 cataacagag atattcccat gagagtgttt ctccaaaagt tgttttaatt tcttttttat
     4261 ctcgaagttc atcttctgta acatttgccc aatacatcat atctgcaatc agtttttcca
     4321 tattcacaat aggtgaaata aaatatgctt tttctatttg cttatctgat aaggcgttca
     4381 tggcgaaata ggcacctatg ctatttgcaa ctatttgaac agatttgtaa tgtttgcaaa
     4441 tcaaatcaaa aagtgatgga aattcttctt ttgcttccca tggatattgt gcagtatagt
     4501 tgagtccaac cacatcacaa tcactaaaaa gaggtttgta atgtgaagac tcctctgcat
     4561 ttccaccttt accatgtata taaataacta ctttatccat aatagttgtc ctcctcaact
     4621 tccgatttgt atactaaatt gaagtataaa atcatcattt cctgttgggc tttcttttta
     4681 ttcccaataa tttaacaaaa tcattaaata agattgtatc tgttggctca aacatcaacc
     4741 attttccgtc atgataggtt tttgtttcat cataaatttt ttgcacttct tttgaataac
     4801 tatttctatc tgtatcaaat tttaatcgtt catctttccc taagataatc ataaatccta
     4861 cacagttttc ccttgcgtac aatgcacaaa gcgtttttcc gccacgacga tatttatact
     4921 cataagtcca cgctttacca cctttgttcc ataaacattc catgtcatac ttttcatcaa
     4981 ttaaggcaca cagtttattc catatagcat ataatgattg cccgactaaa gcagtcattt
     5041 cttctgcatt aggtatttta tccagcatac tcatttctcc tttataactt cttatttatc
     5101 tttgtattta ttgacttcta caaacaagaa tttatctcat acaggcattt ataaatttca
     5161 taggcacgtc catgcgttct gcaacttgtt ctggtgtcat tccgctattt aagaaacgct
     5221 tgcatactat tttcatgttt tctccaactt cgataatatg tttatctggg tcataaaagc
     5281 ggactacacg ttgtccccat gaatgttcta taatagggtg gacatattca atatcatatt
     5341 ctttcagcct atcagcaaat ttatcaaaat catcttcttc aaaatagact tcaaaatttt
     5401 taccgccaaa agaaatatca cttgtaccga taaactcttt gtatgtttca cttgtctgta
     5461 aggctaagcc acctgttaaa gttttatttg ctccaaaatc cataattaca cgaagtccaa
     5521 aaactttttt ataaaactca actgatttat ctatatcagt cactaccaac ataggatttt
     5581 taaatttcat tttcgctacc tccgcaagtt caaattatct gtttccatac ccatattata
     5641 acagtcactt atatttgcta caatgaaaat ctagtttgcc agtttatttt tttgttgtcc
     5701 ttgtggtgca aggttctgtg gattgttgtt ctgtggattt cctgctggct ggttgccttt
     5761 gttcttcaag ataatatcgt cagccttgat gtaccagtcc acatcagccc ctctaaagtt
     5821 ggcatttgcc accgtatcag ctacgggatt gattaactcc acttccgcat tataaggaaa
     5881 gtcctttacg ggaacatcag cggggattga cacttgtatc atgcgttcct gcacactaca
     5941 tttcaaatca taagtacgac gcttaatttc atcacttgtc gttccgtcct cattttctac
     6001 acgcacctca tgtcgaagtg cagagaattt caatactcca aaagtttttt cgttatctaa
     6061 tacaattcca tttgctaatc tcataatcaa ataccccctt atttgctttc tgctggtaac
     6121 atatcatcag ccattaaaat gtagtttgta aatccacgtc ctttgacgtt gtaaccctct
     6181 gcggtaatgc gtgggttaat cagttttact ttctgctctg gcttaaaatg cttctcgcca
     6241 gcttttgcag gcaatacaac gataatgtcg tcggctctct gaatatccga atacaagttg
     6301 taacttcttg atacgggagt gtaacgccca ttgatatgtt gctggtctac tttgttttcc
     6361 cctgcaaatt ccaagtttcc aaaagtctgt gccacattcg gcacgatata ttttaattcc
     6421 atattgtttt acctcgtttc tttctattag tttgattgtt ttgtattctg gcagttaatg
     6481 agataccagc aagcccagac agtaaagggt aaactgtatg ctgacgcact cttgacgatc
     6541 tgggttcttg caggtaatcg gcagacaagc cagaatagaa gtagtctgcc tatttaagtt
     6601 acggcggaga gcgtgatttt tcttttctca tgcagttacc gccttatgat ttcttcatct
     6661 tacggcgttt gaagaagtat gtaccagcca gaccgccagc agaaacaaac atcataatcg
     6721 caaaggcaag aatatttgta ttgtcgcccg tttttggact gtctgttttc gttggtgtat
     6781 ctggtgtagt tggcttctct ggttcttctg gcgtaggtgt ttctggtact tccttaatag
     6841 taaccgtctg cccgtcgtcc tcaatgtcct tatgctccgt aacttttatc ggtttgtctg
     6901 gattgcttaa atcgtataat tcctcaaaag ttacaaactg tttaccgcca agagaagaag
     6961 cgtcaaaagt aaatgcaatc tttacttcca tagtttcact gtcagacgta aatgtgtagt
     7021 cattttcaac ttttttatca ttgatgataa gctctgcatt ttcttctttt aacatctgcc
     7081 agcccacaag ctgatacttt gtaccgactt ctaagccctc taacttgacc gtatcaacaa
     7141 tcgttacgtc cttgccagct tcaatctctt tcttgccgtc cttgtccgta gctgtggtat
     7201 ggattttgat gatacgttct gtgataagta ccgtttgtcc gtcgtcctca atatctttat
     7261 gttccgcaac tttcacgggt tcttctggat tgcttaaatc atacaattct tcaaaagtta
     7321 caaggttctt accgccaaga gcagacgcat tgaatgtata agcgatttcc actttcatag
     7381 cttcatcatc agcgacaaag gtataatcac tttccactcg tttatcacct acaagaagct
     7441 cggcattttc ttttttcaac atctgccagc cttttaactg atactttgta ccttttacaa
     7501 gaccgtctaa tttgaccgta tcaatgatag taacgtcatt ccctgcaagg atagtctttt
     7561 cgccgtcctt gctggtagca gtagtatgga tagtgatttc tttttcgtat tcatcagtca
     7621 gcgtacctaa atcaaccaca accttatttc tggaaatgac aatctcaaac ggtggaataa
     7681 gtttgaagcc tttgttgctt tcacaacgta attcttcaat gatgtaggta tcataaatca
     7741 aagcaccttt gctgtcgtct ggttcagaag taccaaacca cacaccgtcc tcgcttgttt
     7801 ttcctgcatt ggtattgtgc ttgtgggaag cccaatcaga agcagtagag aattgtccgt
     7861 tatcatcagt tacaacaaca tgactttcgc ccgtcgtctt gcttgtgatc ctaaacggaa
     7921 catctgcaag acgcttgtgc gaacctgcac caatttttac gccctcaata tcgccacgtt
     7981 taatctggtt atagatagag tgggcttcgt cagtcaaatc aacgattttt ccattctctg
     8041 tgatttcaaa atcaatcggc tttgcaccgt cagtcaaata tccctctggc ggtttttgtt
     8101 cagacaatct gtattttccg taaggtaata ggtcagcaga agtagaagcg ataccctcaa
     8161 tgtcggtatg gattgtcttt aacacttcat ttttcttgta taacttgctc tcaactaaga
     8221 cggcattctc atttaaggaa atgatttcaa aggcggtatt tttcaaagtc gcaccgcctt
     8281 gagctttcgt gtctttggtt tctaaatctc gtttctggat ttttacaccg ccacgaatga
     8341 ctttatcaga aacatggtat tgattgcttc cagacaatac ggcaaggtcg ccgtcctctg
     8401 taatctgtgt cagatacatt tcttttatct gttcttcgct accgtctgcc tgcatatatg
     8461 caccctctaa taagtaacca gacggacttt ttgtttcttc gacggttagt gttcctaaag
     8521 gaagcacgtt tttaccgtcc tgcatataga agctgtctcc agatacttta taagcgttag
     8581 ctaaacgggt aatgtaatgg atagctccgt cgctgtcttt ttcagcgata gtctttgtta
     8641 cccatgttct tgtaggctgt gctggaagat tgttcttgtt gtaatatcca gcgtagaagt
     8701 tccatgtaaa ctctgctccc tctaaagaag cgtttccctg cgaattggat ttctgtgttt
     8761 ccatgtcaat cttgaatagc tcaatcaagg tatctgttac ttttggtgta tcagatactt
     8821 ttaaagtcgc tgtttttcca gcttccacag ataaagagta aactgtttta tcaattttaa
     8881 atcctgctgg tgcagaaagt tccttgatat atactgtagt ggctcttact tcaacggctt
     8941 ctgtatttcc gctggtatca gtcgtaaggg tggcaagctg tttcgtgcag tctttatcag
     9001 aatacacacc gtatgttgca ccagcgattg aataaatccc gttgccgtct gtaatattgg
     9061 cattggtgga agtcttttga agtttggcat ttccgacagc taacttcgcc cagaattgcc
     9121 ctaactcttg accctcgcca gaatagatat atccgccaca gtcataacgt cctttgtttt
     9181 ctttcacaaa ggcttttgct cctgcgaata cttcatcttg tacggctttt gggatttcat
     9241 cataggaagc tcgcacatta tcgcattgcc agtcaagctg aacacttaat ctctgccaga
     9301 caacaagctg ttttaatagg taggcgtgtt tactgcttat tccgctgtgg ctgtctgtgt
     9361 actgtttcac atactcaata gataaggcaa cgtcgcttat ccggtcggca ctcatgcgtg
     9421 agcttgcgtc tgttctggtc ttatagccgt ttttaaacgc tgtgttgatg tcaatacaat
     9481 aagcgtcctt gccctcaacg gttaaatgtc cctcattaaa ggtagaactg atagaaccgt
     9541 cattcattac ttgttctacg ataccgacac gctctttact ttccgtccaa tactgtgtat
     9601 tagacgcatg aaccgttgaa ctcggtaaag cggtaacgac agttgcaaag gcaagaaagc
     9661 ctgtacacaa tcgttttaat atctttttca taattctaaa tgctcctttc attttggtag
     9721 taaaatagcc gtccactagg aacggctgga aatagaaaag gaacgctgat attgtgcgtt
     9781 ccgtagtcta tgaagtattc aatttttctt gtttcaatac tgatgtgctg taccgtatct
     9841 ttgcatatct gggaaatagg acgtatcaag gctcattcaa tcgtagtaaa ttagtagtat
     9901 tttgatgtgt ttagctcctt gataatgccg atagatacag cgttttagcg gataatcaaa
     9961 tttttagtgt gtttttgata taaaaataat aatacaatac atttgtatag tattattcta
    10021 aaattctata tctaaataaa atcacctcta aaatatttaa tttttatctt tatttgtc
//
LOCUS       DAMKNB010000110        10073 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.116, whole genome shotgun sequence.
ACCESSION   DAMKNB010000110 DAMKNB010000000
VERSION     DAMKNB010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 10073)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10073)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10073
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.116"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            36..1040
                     /locus_tag="PC494_003239"
     CDS             36..1040
                     /locus_tag="PC494_003239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family ABC transporter substrate-binding
                     protein"
                     /protein_id="HDF3913712.1"
                     /translation="MRFKRILILMLTVAMIAGMLVGCANNPSNNPSSSKDNKSDISDK
                     SNSKKSVSMILDIEGTNNEAMNNSALLALNNAQKKLNIDTNKVESDDSSTFSNSIDIL
                     CNDNYDLIIAVGARFAKPLEMVAKKYPKQQFAIIDYEYDKQPSNITSISYEDNKSGYL
                     AGLIAGKMTESDKVGFIGGTKSSSRDKFESGFREGVKFSNSSIRDISVEYADVFKDSK
                     SVESIAKKMMDNGVDIIFSTTEDDSKAVIDAVRAKNKKVIATNKDQHELAPENVISSV
                     VKDFENPTYNLIQSFVKGNYKGGKVIENTVKSGSTGLAQNSSQNIPPDVLEYVNKNNK
                     "
     gene            1166..2278
                     /locus_tag="PC494_003240"
     CDS             1166..2278
                     /locus_tag="PC494_003240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family ABC transporter substrate-binding
                     protein"
                     /protein_id="HDF3913713.1"
                     /translation="MKIKRILMACFVVVFTIFILAICNFDFGFDKVNKNNSNIDSAKS
                     KQNESKSLPTSAEKDKSNSKSKNKEDDTEDDSYVRKTIGVLLDTENLNNESYNNNVLS
                     ALKRADEDFDVRIKLEKPKTSKSFKESIEKLHKYEPDLIIAVGARFAEPIKEAATKYP
                     KQQFAIVDYTYKVQPANVISVSFQDNVTGYLAGLIAGKMTDTGKVGFIGGVEGSSRDK
                     YESGFRKGLKTSNKDAELLVKYSNIFENPESARTIAKEMRDSDRDVVFSATEDDSKRA
                     IQVARENGGKVIAINKDQYDMAPDNVISSIIKDVEQPVYELIKNVAKDGFKGSKVMEF
                     KIKDGELGLTSKSSRNIPPDVLEYIKKEYNKVKDTY"
     gene            2634..3395
                     /locus_tag="PC494_003241"
     CDS             2634..3395
                     /locus_tag="PC494_003241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3913714.1"
                     /translation="MEFTREPFILDDDLCLALVDKRISYLMENELKLRNIEIIKTIEC
                     KELYESIKYHPDICICNLGKGDIIVAPNVYNQYKELLSRYKFNIIKGEANLLNRYPYD
                     IPYNIAIVGDYAIHNFKYTDKAILDYIENNKLKKINIEQGYSKCSICIVDRTSIITSD
                     KGIWKSMKNTEIECLLIEKGHINLFEMNYGFIGGCTGLISKDKLAFCGDVKKHPDYER
                     IKSFVESKNKEIVTLSCENLLDIGSIVPLMTRKER"
     gene            3398..4216
                     /locus_tag="PC494_003242"
     CDS             3398..4216
                     /locus_tag="PC494_003242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative sporulation protein YtxC"
                     /protein_id="HDF3913715.1"
                     /translation="MVEKDNISSMKFLRNNNVNDRLIYTNDIVEVVIDSAKQEVLNKK
                     ILNGTKTEQRALNIDEISTEITSMIISIMKEKLLKEYILKCYGRTYPEDKNNIYIYSL
                     NIFAKKEIFMRETVFTRVRNYIEENDFINVEGFIRFRMREFMKYISAIGDIAVEEYLI
                     KKDQDEFIRVLKYFIDTQEEKIDLLKVHIMEDNTFVLYDKNGNKIDSIDDEEIINMVI
                     RENLNYEDFLISTLLTLCPKKIEILDLLNNNCSKEIIDTVEAIFENKVSIIMEN"
     gene            4396..4998
                     /locus_tag="PC494_003243"
     CDS             4396..4998
                     /locus_tag="PC494_003243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF445 family protein"
                     /protein_id="HDF3913716.1"
                     /translation="MDNLIRILILAVIGGFIGYVTNVVAIRLIFRPIEPIKIPILNIE
                     IVGLIPKRRAEIAANVGEIIQEEFLSMDEILANIITDEDKEEVVRYIKARVKIIIHEK
                     VSFIPSGIKNMIQDYLGEIIESEVKQSIDELSKNIINKANERIDIQKMVEDKINELDL
                     YELEEIIIRIAKKELKHIEFLGLVLGFLIGIAQGLITMFI"
     misc_binding    5559..5796
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            5860..7779
                     /gene="thrS"
                     /locus_tag="PC494_003244"
     CDS             5860..7779
                     /gene="thrS"
                     /locus_tag="PC494_003244"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HDF3913717.1"
                     /translation="MIKVALKDGSIKEFENAISVMDVAKSISEGLARNVVAASVNGEV
                     VGLDHIIDTDCDLNLFKFEDKEGKEVFRHTSAHILAQAIKRLYPEAKLAIGPSIENGF
                     YYDIDLDHRLVPEDLEKIEAEMKKIAKEDLKIERFELPRNEALELMKEQGEDYKVELI
                     SDLPESEIISFYKQGDFTDLCRGPHLPSTKKVKAVKLQSVAGAYWRGDENNKMLQRIY
                     GTSFEKNKDLEEYLHLLEEAKKRDHRKLGKELGLFMIPEEGPGFPMFLPKGMELKNEL
                     LKFWREIHRKAGYIEIESPIILNRKLWETSGHWYHYKENMYTVKIDDEDYAIKPMNCP
                     GGLIYYNSQLHSYRDFPMRVAELGRVHRHELSGALQGLMRVRAFTQDDSHIFMLPEQI
                     KDEIKGVANLIDGIYKTFGFEYNLELSTRPENSMGSDEEWEAAENGLREALEELGLPY
                     TINEGDGAFYGPKIDFHLKDCLGRTWQCGTIQLDMQLPRQFDNTYIGQDGEKHRPVMI
                     HRVAFGSIERFIGILIEHYAGKFPVWLSPTQVKILPISDKFMDYANEVKKELFDKGIR
                     VELDDRAEKIGFKIREAQLEKVPYMLIVGEKEVADNNVSVRSRDKGEIGSIKLDEFIA
                     SISKEIESRESIIQD"
     gene            8547..9638
                     /locus_tag="PC494_003245"
     CDS             8547..9638
                     /locus_tag="PC494_003245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rpn family recombination-promoting
                     nuclease/putative transposase"
                     /protein_id="HDF3913718.1"
                     /translation="MIEKVEEKSKIIKTSKEYKRTIIEEKDKEWTKKLNDILSRSSFS
                     NDELDKIKALIPKEILTNENVGEVVTEDGYAKPEYDEVFKSLFTLNNEYDLLVNFIND
                     ILKDAPYANRNIKPFTQIKRIIRVETDPTINYIGEKRPRLDILAEDEENNHINIEMQR
                     AFENDYLERAEYYLSRVHGRKLEEGKEYKEIGKTIGIHILNHVKYNHIEDYVNCLRLT
                     MDGHPDIYSSKTALYFIELPKIHKSDYIVNRIMLWGKLISNPSSLDVRVIAKNDSIIK
                     KALDRLKELGSNEEYLLNLKRGAYIMNKSRNFKEEIERETAIRVAKEKDYKIIIMLKK
                     NGFKLDDILNKFNDFDLSEDEIKEVYENN"
BASE COUNT         4087 a          969 c         1788 g         3229 t
ORIGIN      
        1 taaaaatatc gtaaatgtat gaggagtgaa atttaatgcg tttcaaaaga atattgatat
       61 tgatgttaac tgtagcaatg atagctggaa tgttggttgg gtgtgctaat aacccaagca
      121 ataatcctag ctctagcaaa gataataaaa gtgatataag cgataaaagt aattcaaaaa
      181 aatctgtatc aatgatacta gatattgaag gaacaaataa tgaagctatg aataattcag
      241 ctttattagc attaaacaat gctcaaaaaa aacttaatat agatacaaac aaagtggaat
      301 cagatgattc ctcaactttt tctaatagta tagatatttt atgtaatgac aattacgatt
      361 taattatagc tgtaggagct agatttgcaa aaccattgga gatggtagcc aagaaatatc
      421 caaagcaaca atttgcaatt atagactatg agtatgacaa gcaaccttct aatataactt
      481 caatttctta tgaagataat aaatctggat acctagctgg attaattgct ggaaaaatga
      541 ctgaaagcga taaggttggt tttataggag gaacaaagag ttctagtagg gataaatttg
      601 aatcaggttt tagagagggt gttaaatttt ctaatagtag tataagggat atttcagttg
      661 agtatgcaga tgtttttaaa gatagcaaat cagtagaatc tatagctaaa aaaatgatgg
      721 ataatggagt ggatattatt ttttctacta ctgaagatga ttcaaaagct gtaatagatg
      781 cagtaagggc aaaaaataaa aaagttatag caacgaataa agatcaacat gagttagctc
      841 cagaaaatgt tataagttct gttgtaaaag attttgagaa tcctacttat aatctgatac
      901 aaagctttgt aaaaggaaat tataaaggcg gaaaagttat agaaaacaca gttaagtctg
      961 gaagtactgg gcttgcccaa aatagttctc aaaatattcc tccagatgtg ttagaatatg
     1021 ttaataagaa caataaataa tctactataa tatccaagaa tacttatgac tttagttatg
     1081 aggtgaaatg gatgttataa tagacatata tagaaagaca tatgcagagg taggttagac
     1141 ctatctaaat cagggagtga attttgtgaa aataaaaagg atattgatgg cttgctttgt
     1201 agtagttttt acaattttta tattagctat atgtaatttt gattttggat ttgataaagt
     1261 aaataagaat aattctaata tagatagtgc taaatcgaaa cagaatgagt ctaaaagttt
     1321 gccaacttca gcagaaaagg ataaatcaaa tagcaaaagt aagaataaag aagatgacac
     1381 agaagatgat tcatatgtaa gaaaaactat tggagtattg ttagataccg aaaacttaaa
     1441 taacgaatca tataataaca atgtactatc agccttaaaa agggctgacg aagattttga
     1501 tgttaggata aaacttgaaa aaccaaagac ttctaaaagt tttaaagaga gtatagaaaa
     1561 actgcataag tatgaaccag atttgataat agcagttgga gccagatttg cagagccaat
     1621 taaagaagct gctactaaat atcccaaaca gcaatttgca atagttgact atacttataa
     1681 agttcagcca gctaatgtaa tttctgtatc atttcaagat aatgttactg gatatttagc
     1741 aggacttatt gcaggtaaaa tgactgatac tgggaaagtc ggttttatag gaggagttga
     1801 gggttctagt agagataagt atgaatctgg atttagaaag gggcttaaaa cttcaaataa
     1861 agatgctgag ttactagtta agtattcaaa tatatttgaa aaccctgaat cagctagaac
     1921 tattgcaaag gaaatgagag attctgatag agatgttgta ttttcagcta cagaggatga
     1981 tagcaaaaga gctattcagg tagcaagaga aaatggtggt aaagttatag ctattaataa
     2041 agaccaatac gatatggctc cagataatgt aataagttca attataaaag atgtagaaca
     2101 acctgtatat gaactgataa agaacgttgc aaaagatggt tttaagggaa gtaaagtaat
     2161 ggaatttaaa ataaaagatg gagaacttgg cttgacttca aagagcagta gaaatatacc
     2221 accagatgtt ttggaataca taaaaaaaga gtataacaaa gtgaaagata catattaatt
     2281 attgatgtag aagattataa aaatatactg cttaagttta gattggtgat aaaaggatat
     2341 atttattaaa tttagtctaa ctgtacaaaa tatattgatt gagtttaggt tagcaataaa
     2401 aagatatatt tattaaattt gtgctaactg tacggaatat actgcttaag tttagattag
     2461 tgataaaaag atatatttat taaatttgaa ccaactgtac aaagctatac taattaagct
     2521 tagattaact atataaaatt ataacaataa gtgtgtgggc agaaaaattc tgctacacac
     2581 tttatttata ttcacataaa aaatttatca aaaaaaagaa aaaggagtaa aaaatggaat
     2641 ttacaagaga accatttata ctagatgacg atttgtgtct agctttggtg gacaaaagaa
     2701 ttagttatct aatggaaaat gaattaaaat taagaaatat agagataata aaaacaatag
     2761 aatgtaaaga attatatgaa agcataaaat atcacccgga tatatgtatt tgtaatttag
     2821 gaaaaggaga tataattgtt gcgccgaatg tatataatca atacaaagag ttattaagta
     2881 gatataaatt taatataatt aagggagaag ctaatttatt aaatagatac ccttatgata
     2941 taccttacaa tattgcgata gttggtgact atgctataca caattttaag tatactgaca
     3001 aagcaatatt agattatatt gaaaataata aacttaaaaa gataaatata gagcagggct
     3061 attctaaatg ctcaatctgt atagtagata gaacgtctat aataacatca gataaaggta
     3121 tttggaaaag tatgaagaat acagaaatag agtgtttatt gatagaaaaa ggtcacataa
     3181 atttatttga gatgaattat ggatttatag gtggatgtac agggttgatt tctaaggata
     3241 aactagcttt ttgtggagat gttaaaaaac atcctgacta tgaacgtata aaaagttttg
     3301 tagaaagtaa aaacaaggag atagttacac ttagctgtga aaatttacta gatataggtt
     3361 ctatagttcc tctcatgaca agaaaggagc gataactttg gttgagaagg ataatatttc
     3421 ttccatgaaa tttttgagga ataataatgt aaacgataga ttaatatata cgaatgacat
     3481 tgtagaagta gtgatagatt ctgcaaagca agaagtgtta aataaaaaaa tacttaatgg
     3541 tactaaaact gaacaaagag ctttaaatat tgatgagata tcaacggaaa taactagtat
     3601 gataataagt ataatgaaag agaaactttt gaaagaatac attctaaaat gctatgggcg
     3661 tacatatcct gaagataaaa ataatatata catatattca ctgaacatat ttgctaaaaa
     3721 agagattttt atgagagaaa cagtatttac tagggtgaga aattatatag aagaaaatga
     3781 ttttataaat gtagaaggtt ttattagatt tagaatgaga gaatttatga aatatatttc
     3841 tgctataggt gatattgcag ttgaggagta tttaataaag aaagaccaag atgaatttat
     3901 aagagtttta aaatacttta tagatactca agaagaaaag attgatttgc ttaaagttca
     3961 tataatggaa gataatacat ttgttttata cgataaaaat ggaaataaga tagacagtat
     4021 agatgatgaa gaaattataa atatggtaat aagagaaaat ttaaattatg aggacttttt
     4081 aataagtacc ttattaactc tatgtcccaa aaaaatagaa atattggatt tgttaaataa
     4141 taattgctca aaggaaatta tagatactgt agaagcaatt tttgaaaata aagttagtat
     4201 aattatggaa aactagaatc taagcatata aaagctatcc atataaaatt aaaaaaattc
     4261 tttttaaatc gacacaaaag acttataatt gtatataaag ctatagtata actagtgtta
     4321 ttaagtataa agaatatcta cttgattaat acaatatagc tggcaaatat acaattgata
     4381 aggagtaatt ttataatgga taatttaatt aggatactga tattagctgt tattggtgga
     4441 tttataggtt atgttacgaa tgtagttgct ataagactga tatttagacc aatagagcct
     4501 attaaaatac ctattttaaa tatagaaata gtaggtctta taccaaagag aagagcagaa
     4561 atagcagcaa atgtaggaga aataattcaa gaagaatttc tttctatgga cgaaatactt
     4621 gcaaatatca ttactgacga agataaggaa gaagttgtaa gatacataaa agcaagggta
     4681 aaaattataa tacatgagaa agtttcattt atcccgagtg gtataaaaaa catgatacaa
     4741 gattatctag gagagataat tgagtctgaa gttaagcaaa gtatagatga attgagtaaa
     4801 aatataataa ataaagcaaa tgaacgtata gatatacaaa aaatggtcga agataagatt
     4861 aatgaactag atttatatga attggaagag ataataataa gaatagctaa gaaagaatta
     4921 aaacatatag agtttttggg gcttgtctta gggtttttaa taggtatagc tcaagggtta
     4981 attactatgt ttatttaaat atatgagaag tagcatttat ttaagtacta attatattta
     5041 cctatttgag tgaattactt attaataaca tttagatatt aattgtattt acctatttga
     5101 gtaaattact tattaatagc atttagatat taattgtatt tacctatttg agtgaattac
     5161 ttattaatag catttagata ttaattgtat ttatttattt gattgtgtta cttattaata
     5221 gtatttaagt atttactgta ctacttatta actatattaa gtattgattg tatttaagta
     5281 tacaaaacct aaaaagagta caaaaattag aagttagttt taataaaaat tagttttagt
     5341 atttatctag tcatatctat catgcatgtg gatacgtttt aaaaatttta aatttatgaa
     5401 aatattataa tatcactata aatcaagaga ttaatttaat ataaaaatat aagaatattg
     5461 gtttacagct gattgagatg aaaaataatg ggtaattaat atattacatt aatgttgatt
     5521 gatgtataac tatctgttat aatgaaaata tattaaaaat catagtgttg aagaggaaga
     5581 gtagagtaga aaccattctc agagaatttg ggtctatggc tgagagccca tgtaataggt
     5641 ctatttgaaa actaccttgg agctgagctt attagcagta tttgttttgt actatacgtg
     5701 aaagtgctcg ggtgacgacc ttatagtcat caagagggtt gtatatactt gtatacgcca
     5761 acttgggtgg aaccgcgaat taatatcgtc ccaaacatat ttggggcgat tttttattac
     5821 aaaaaatcta aaaattattt caataaggag gaaaaaacaa tgattaaagt tgctttaaaa
     5881 gatggctcaa taaaagaatt tgaaaatgct atttctgtta tggatgtagc taaatccatt
     5941 agtgaaggat tagctagaaa tgtggtagca gcgtctgtga acggagaggt tgtaggtctg
     6001 gaccacatta tagatactga ttgtgacttg aatttattta agtttgaaga taaagaaggt
     6061 aaggaagttt ttagacatac atcagcgcat atattagctc aagctataaa aagactttac
     6121 ccagaagcaa agcttgctat aggaccaagt atagaaaatg gattctacta tgatatagat
     6181 ttagaccata gattagttcc agaggaccta gagaaaatag aagctgaaat gaaaaaaata
     6241 gctaaagaag atttaaaaat agaaagattt gaacttccta gaaatgaagc tttagagctt
     6301 atgaaagaac aaggagaaga ctataaggta gaacttatat ctgatttacc tgaaagtgaa
     6361 ataatatctt tctacaagca aggtgatttt actgatttat gtagaggacc acatttacca
     6421 tctactaaaa aggtaaaagc tgttaaatta caaagtgtag caggtgcata ttggcgtggt
     6481 gacgaaaata ataagatgct tcaaagaata tatggaactt cttttgagaa aaacaaagac
     6541 ttagaagagt acttacattt actagaagaa gctaaaaaga gagaccacag aaaattaggt
     6601 aaagaattag gattatttat gatacctgaa gaaggtccag gattccctat gtttttacca
     6661 aaaggtatgg aacttaaaaa tgaattatta aaattctgga gagaaataca cagaaaagct
     6721 ggatatattg agatagaatc tccaatcata ttaaatagaa aattatggga gacttcagga
     6781 cactggtatc attacaaaga aaatatgtat acagttaaaa tagatgatga ggattatgct
     6841 ataaaaccta tgaactgtcc tggtggatta atttactata actctcaact acattcatat
     6901 agagatttcc caatgagagt tgcagagctt ggtagagttc atagacatga gttatctggt
     6961 gcattacaag gattaatgag agttagagca tttactcaag acgattcaca tatattcatg
     7021 ttaccagagc aaattaagga cgaaataaaa ggagtagcta acttaataga tggtatatac
     7081 aaaacttttg gatttgaata taatttagaa ttatctacaa gaccagagaa ctctatggga
     7141 agcgacgaag agtgggaagc agcagaaaat ggattaagag aagctttaga agagttaggt
     7201 ctaccatata ctattaatga gggtgatgga gcattctatg gtcctaagat agacttccat
     7261 ctaaaagatt gtttaggaag aacttggcaa tgtggtacta tccaattaga tatgcaactt
     7321 ccaagacaat ttgataatac ttatattggt caagatggtg aaaagcatag accagttatg
     7381 attcataggg ttgcttttgg tagtatagaa agatttatag gtatattaat agagcattat
     7441 gctggtaaat tcccagtttg gttatctcca actcaagtta agatacttcc tatatctgat
     7501 aaatttatgg attatgcaaa tgaagttaag aaagagttat ttgataaggg tataagagtt
     7561 gaattagatg atagagctga aaaaattgga tttaagataa gagaagctca gcttgaaaaa
     7621 gtgccataca tgttaatagt aggtgaaaaa gaagtagctg ataataatgt ttctgttaga
     7681 tcaagagata aaggtgaaat aggtagtatt aaattagatg aatttatagc tagtatttca
     7741 aaagaaattg aatcaagaga aagtattatt caagactaat atatattatt ttagtagcta
     7801 agatattgtt atataagata agtttaatca atatgttgat atgttgatgc atagtgatta
     7861 aatttatgaa aagatgagta taattagagg tacagttaat catattttta tgattaatgt
     7921 acctctagtt ttttgtatgg tagatttatt aataaatata tcatagaagt gttttgaaca
     7981 tggaaatatt tatgtgcatt ctttaaataa aagtttattt tttgagtgat aattaagtgc
     8041 ttgttggtaa ggttatggtt gtaaaaatca taactttatt ttcatatttg ttccattttc
     8101 ataaaaatta ttatcccttt aagaaaattt cttaatcctc ttgaaatatt tcctttttag
     8161 tctaaagtta aatttctttc ttcaaaatga atatttaaat gaactaaaat ttaagtacat
     8221 tttctaatct tatgagtcta tttttcatag ataattgccc tataatagaa gaatctatgt
     8281 tggagctatg tggtgacaat aacagtattg tcagtgatta attaatgctt tataaatgat
     8341 taattagtgt tttatgttat ttttggactt accctctata catagattaa tttatttaac
     8401 tttagataga gagagaatgt caagtacata cacagacatt agagtttaag aaagtgttta
     8461 tggagcaaga acttttaaaa gaggtagtga cttagtttaa tttcaagaaa tgataaatac
     8521 aaaagaggaa aaagagaggt gttgaaatga tagaaaaagt agaagaaaaa tctaagatta
     8581 ttaaaacatc aaaagaatat aagcgaacta taattgaaga aaaagataaa gaatggacca
     8641 aaaaattaaa tgatatactt agtagaagta gtttttctaa tgatgaatta gataaaatca
     8701 aggcgttaat tccaaaagag attttgacta atgaaaatgt tggagaagtt gtgactgaag
     8761 atggatatgc taagcccgag tatgatgagg tatttaaatc attgttcact ttaaataatg
     8821 aatatgattt acttgtaaat tttataaatg atatcctaaa agatgctcca tatgctaaca
     8881 ggaatatcaa accgttcact caaataaaga gaataattag agttgaaact gacccaacaa
     8941 ttaattacat tggagagaaa agacctagac ttgatatttt ggctgaagat gaagaaaata
     9001 atcatataaa tattgagatg caaagagctt ttgagaacga ttatttggaa agagctgaat
     9061 attatcttag tcgtgtacat ggtagaaagt tagaagaagg taaagagtat aaagaaattg
     9121 gaaaaactat tggaatacat atactaaatc atgtaaaata taatcacata gaagattatg
     9181 taaattgcct gagattaaca atggacgggc atccagatat ttattctagt aaaactgcat
     9241 tatattttat agagcttcca aaaattcata aatctgacta tatagtaaat agaattatgc
     9301 tatggggaaa acttattagt aatccttcta gcttagatgt aagagttata gctaagaatg
     9361 attctattat taaaaaagca cttgatagat taaaagaatt aggtagcaat gaagaatatt
     9421 tattaaatct gaaaagaggt gcttatatca tgaataaaag tagaaatttt aaagaagaga
     9481 ttgaaagaga gacagcaatt agagttgcaa aagaaaaaga ttataaaata attataatgt
     9541 tgaaaaaaaa tggttttaaa ttagatgaca tattaaataa atttaatgat tttgacttaa
     9601 gtgaagatga gataaaagaa gtatatgaaa ataattgatg ataaaaagtg aacttatata
     9661 agtttgctga atcggagtct ggaaatattt atgtgtattt tttaatgaat aaaaatttat
     9721 tttaaaaaca ataatttaga ggtacagtta attatatttt tatgatactg tacttctagt
     9781 tttttctatt gtagatttat tatttactaa taaatctaca atagaagtgc ttttgttgta
     9841 agaatcattt tatctaatga ttgtttttta taatagttaa atttccattt gtagtgttta
     9901 aatataaatc tataacagca tttctataaa tgttataaat cactataatg attcaactca
     9961 aagttactgc ttaaagaagc agagatttta tcaaggtata tcatggaaaa aaatatttta
    10021 ttgtaatatt tataagattt tattatggaa ataatgtaaa aactttataa ata
//
LOCUS       DAMKNB010000111         9478 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.117, whole genome shotgun sequence.
ACCESSION   DAMKNB010000111 DAMKNB010000000
VERSION     DAMKNB010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 9478)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9478)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9478
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.117"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            complement(130..783)
                     /locus_tag="PC494_003246"
     CDS             complement(130..783)
                     /locus_tag="PC494_003246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDF3913719.1"
                     /translation="MKVDPLTTQVYDYISKKIQNGEYEANQRITESEICKSIGVSRTP
                     AREALTRLAGENLLEKIPNKGFVVKEFQEKEKLDTYSVIGVLDALAGSSALQNLTESD
                     LVKMEELTEMMAVSIKYKNYNSYLKLSNEFHDIYITKSDNQVLVNLLNSLRYNFMSKS
                     YTSDNEDELYKMLTYSNNQHIEVVKSMRENDLENVERVLREHWKTIPIAEMKKEKLL"
     gene            complement(1028..2893)
                     /locus_tag="PC494_003247"
     CDS             complement(1028..2893)
                     /locus_tag="PC494_003247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 13 protein"
                     /protein_id="HDF3913720.1"
                     /translation="MQSVIEYNSWDKNFKAPFGALKFDEELTICVKVNEGYNIKSISL
                     EINREEEMRTITLNEELDNDKLGKCFCGKIEKFDGTGVYFYYFKVDVEMDGQIKTLFY
                     GKNRDNGYSCEYNYSDINKYQITVYKDFKVPTWYKEGILYHIFVDRFNNGNRSGKVDN
                     PKKNSFIYGNWEDTPMYIKDSQGDVIRWDFHGGNLRGIINKLGYLKKLGVSILYLSPI
                     FEASSNHKYDTGDYKKIDPMFGDEDTFKELIDKAKEKGISIVLDGVFSHTGADSKYFN
                     MYGNYNSLGAYQSKESPYYSWYMFEEFPQKYKSWWDVKTLPNINELEHSYMDYIIYDN
                     DSVINKWVNMGIKGWRLDVADELPTKFIRELKKELKKADDDSILIGEVWEDASNKISY
                     GQRRSYLLGEELDSVMGYPFRNNMFSFLKGEINSYELCNRYMQIKENYPKESFRSNLN
                     LIGTHDVTRAKTELNDDVDLVKLAVAIQMTFEGVPYIYYGDEAGLCGGVDPDNRRTYP
                     WKNEDEDMLNFYRDVIKIRNKNKLLSSGNTEFIYTNNDSVFSFIRVNENNDRMLILVN
                     RSENVESISLCIESSFIEEIPIKYSLKNANSTIQIENNELKVDLDSKSFRIFRVN"
     gene            complement(2898..5318)
                     /locus_tag="PC494_003248"
     CDS             complement(2898..5318)
                     /locus_tag="PC494_003248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen/starch/alpha-glucan phosphorylase"
                     /protein_id="HDF3913721.1"
                     /translation="MVTISKKKFKQKFEVKMYSLYAQSIKEATDEQLLNVLCSLLKDE
                     IAKKWVATKLDKKKEVYYFSLEFLIGRQLKSNLLNLNIEEEVREGLSELGINLDDLIE
                     AEVDPALGNGGLGRLAACFLDSMASLNISGQGYGIRYKYGLFEQKFVNGYQVEVPDNW
                     LTEGRYAWETVRPNEATMVKFGGEVELIKEGSHLKVIHKNYLPVMAMPYDIPIIGYQN
                     QCINTLRLFKSEIPKRDFGELTSNALNYSGSYEEALKHKYYTEEISQVLYPDDSNYAG
                     KLLRLKQEYFFVSAGIQDIIRKYKKNKLNINNLFDKVAIHINDTHPTLCIPELMRILL
                     DEENLSWDEAWEITKKTVSYTNHTIMSEAMEKWPVSMMKELLPRIYMIIEEINRRYVE
                     ELNNKGYDQDRIKRMSIIDCDNINMANLCIVTSHSVNGVAKLHTHILETEVLKDFYQD
                     EPNKFNNKTNGIAHRRWLISSNPQLSNLITDLIGDSWKKDTLQLKNIEKFKNDSSVLQ
                     RLDDIKYNNKANLAKFIKDKYDLNVDPSSIFDVQVKRLHAYKRQLLNIFNVLHMYHEL
                     LDNPNLNLDPRTFIFGAKAAPGYYLAKCIIKFINSVASTINNDVRVKDKLKVVFLENY
                     GVSLAEIIIPAANVSEQISTTTKEASGTSNMKFMMNGAITLATLDGANVEICEQVGKE
                     NMFLFGLSAEQVLNYNKYGGYSSLDLYHSNMDIKRVVDDLINGFIPNLGEEGRSIYNS
                     LTTYNDEYFVLRDFENYGQAQADINRLYRDKEKWNKMSLVNIANSGFFSSDRTISEYA
                     KDIWFKRV"
     gene            complement(5332..6774)
                     /gene="glgA"
                     /locus_tag="PC494_003249"
     CDS             complement(5332..6774)
                     /gene="glgA"
                     /locus_tag="PC494_003249"
                     /EC_number="2.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011053260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen synthase GlgA"
                     /protein_id="HDF3913722.1"
                     /translation="MKVFYVTAECWPFAKTGGLGDVSYALPKELKKEGVDVRVIMPKY
                     STIPSYLKDQLKEIAVFSVRVGWRNQYCGLLEMELDGVKFYFIDNEFYFRREDERKSI
                     YGYGDDAERYTFFTDAVLEAISRIDFYPDVIHINDWHTGMLPLILKERYATLEGYKNI
                     KTMYTIHNLQYQGVFDKHVLYDILDLPQKYFDNGDIEYYGSINFMKAGINFADKIITV
                     SPTYANEIQTSFYGEQLDGLLRKESGKLKGILNGIDYDLNDPAKDKDIFVHYDVDSID
                     KKVENKLRLQDILGLKKDSSIPLIGIVSRLVSQKGFDLIAYMMPELMREDLQIVVLGT
                     GEHQYQSMFNYYDSNFSDKVSARITFNASLAQQIYAASDMFLMPSLFEPCGIGQMLAM
                     RYGSLPIVRETGGLRDTVTPYNKFTGEGNGFSFKNYNAHEMFFCLKNAIKVFKDKEKW
                     IKLVENAMKTDNSWKKSAKEYIETYRDICD"
     gene            complement(6803..7933)
                     /gene="glgD"
                     /locus_tag="PC494_003250"
     CDS             complement(6803..7933)
                     /gene="glgD"
                     /locus_tag="PC494_003250"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase subunit
                     GlgD"
                     /protein_id="HDF3913723.1"
                     /translation="MRNECLGIINLNKKGDPAINKLNYGRPIASTPIAGRYRIIDFAL
                     SNMINSGITKVGIFAKEKYRSLTDHIGSGKDWDLSRKKGGLSIFSPENTKYRNTYSHR
                     EGDIYTILANLDYIEKSEEEYILIAPSYMLCNLNYSQALEYHKKSHNDITIIYKNVNN
                     ANKDFAGNLTLNLDSNNRVINVGNNLGKFPRANICMETYIMKREDFVECIYNIVNKGN
                     YCYLEEFIIEEAENMKIGAYEYTGYLKCVNSVESYFEMSKDLLNLEVADELLYSERKI
                     FTKEKNESPTIYTDSAKVENSFIASGCLIEGTVKDSIIFRKVNVEKGTVIENSIVMQN
                     CVIKSNAKLYNAILDKNTSVSNGKELRGDEKYPLVVEKNTNI"
     gene            complement(7935..9095)
                     /locus_tag="PC494_003251"
     CDS             complement(7935..9095)
                     /locus_tag="PC494_003251"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase"
                     /protein_id="HDF3913724.1"
                     /translation="MKKEMLAMILAGGQGSRLGVFTKRIAKPAVSFGGKYRIIDFVLS
                     NCSNSGIDTVGVLTQYRPLILNSHIGMGSHWDLDRINGGVYVLQPFMNEKEGNWYNGT
                     AHAIYQNMDFVDTYNPEYVLILSGDHIYKMDYSKMLKFHKEKGSKATIAVIEVPWDEA
                     SRFGIMNTNEDSSIYEFEEKPSEPKSNLASMGVYIFDWKMLRNYFKEAEKNPEINYDD
                     FGKNLIPKMLEDNVGMYAYPFKGYWRDVGTIQSLWDANMDIIKSPETLDLADPKWKIY
                     TNTMAMPPQYIGKNANVHRSMIADGCRILGEVGNSVLSHGVVVGKGSKVIDSVIMPNV
                     VIGENVTIEKAMIGECATINDNVQIKNVNNEINVVSEYENIEPRCVLIEGGL"
BASE COUNT         3005 a         1728 c          922 g         3823 t
ORIGIN      
        1 aatttaaata cattattcta tcgtagtgcc ttagagtttt tatttgtatt taaagttaaa
       61 tttattcttg tttttccttt aatatttaat agtaaaacaa caaaattata aaaaaaataa
      121 agagaaactt tataaaagct tctctttttt catctctgct ataggtatcg ttttccaatg
      181 ttctctcaaa actctttcaa cattttctaa atcattctcc ctcatagatt ttactacttc
      241 aatatgttga ttattgctgt atgtcaacat tttatataac tcatcttcat tatcactagt
      301 atatgacttt gacataaaat tatatcttaa agagttcaat agatttacta acacctgatt
      361 atctgattta gttatgtata tatcgtgaaa ttcattactt aattttaaat agctattgta
      421 atttttatac tttatagaga ccgccatcat ttccgttaat tcttccattt ttactaggtc
      481 tgattcagtt aaattttgta atgctgaaga accggctaac gcatccaata ctccaattac
      541 ggaataggtg tctaatttct ccttttcctg aaattctttt actacaaatc ccttattagg
      601 tattttttct agtaaatttt cacctgctaa cctagttaat gcttctctcg ctggtgttct
      661 actaactccg atagatttac aaatctcaga ttcagtaatt ctctgattag cttcatactc
      721 tccattttgg attttctttg atatatagtc atatacttga gttgtaagtg gatctacctt
      781 cataagacgt tcctccatat taagattata aaagttaaat ctccctacaa ctttggtaga
      841 gagttcagtt ttatcttact aatttatata atatcacaat tatgatattt tttatacttc
      901 tttgtaatat tttgaaatac taaaattctt atgataattt atacaaaaaa agtagaaaaa
      961 gttttgataa aacaaaactc tttccacatt caccttattt tctatttatt tttctaaaaa
     1021 aagatattta atttactcta aaaattctaa atgatttaga gtctaaatct actttcaact
     1081 cattattttc aatttgtata gtactatttg catttttaag actatacttt ataggtattt
     1141 cctcaataaa actactctct atacataatg atatactttc cacattttca cttctattta
     1201 ctaaaattaa cattctatca ttattttcat taactctaat aaaagaaaat acagaatcat
     1261 tattagtata tataaattct gtatttccag aacttaaaag tttattctta tttctaattt
     1321 ttataacatc tctataaaaa ttaagcatat cttcgtcttc atttttccat ggataagttc
     1381 ttctattatc tgggtcaaca cctccacaaa gacctgcttc atctccataa tatatatatg
     1441 gtactccttc aaatgtcatc tgtatagcta cagcaagctt cactaaatct acatcatcat
     1501 ttaattccgt tttagctctt gtaacatcat gtgttccaat taaatttaaa ttagacctaa
     1561 atgattcttt tggataattt tctttaatct gcatatatct attacaaagt tcatatgaat
     1621 taatttctcc ttttaagaaa gaaaacatgt tatttctaaa aggataaccc ataacagaat
     1681 ctaattcttc acctaataaa taacttcttc tctgaccata gctaatctta tttgatgcat
     1741 cttcccatac ttcacctata agaattgagt catcatctgc cttttttaat tcctttttta
     1801 actctcttat aaacttagtt ggtaattcgt ctgcaacatc tagtctccag cccttaatac
     1861 ccatatttac ccatttattt ataacgctat cattgtcata tattatataa tccatatagc
     1921 tatgttctaa ttcatttata tttggcaatg tcttaacatc ccaccaactt ttatattttt
     1981 gaggaaattc ttcaaacata taccatgaat aatatggaga ttctttagat tgatatgccc
     2041 ctaaactatt atagtttcca tacatattaa aatatttact atctgctcca gtatgactaa
     2101 aaactccatc taatactatt gatatacctt tttcttttgc tttatcaata agttctttaa
     2161 atgtatcttc atctccaaac attgggtcaa tttttttata gtcacctgta tcatacttat
     2221 gattactaga ggcttcaaat atagggctta gatatagtat acttacacct aattttttta
     2281 aatatccaag tttattgatt atccctctta aatttccacc atggaaatcc catcttataa
     2341 catccccttg actatccttt atgtacatag gtgtatcttc ccaatttcca tatatgaaac
     2401 tatttttttt aggattatca accttaccac tacgatttcc attattgaat ctatctacaa
     2461 atatatgata aagtattcct tctttgtacc atgttggtac tttaaaatct ttgtaaacag
     2521 tgatttgata tttattaata tcactataat tatattcaca agaatatcca ttatctctgt
     2581 tttttccata aaataaagtc tttatctgac catccatttc aacatcaact ttaaagtaat
     2641 aaaaataaac acctgtacca tcaaactttt caatcttacc acaaaagcac tttccaagtt
     2701 tatcattatc taattcttca tttaaagtta ttgttctcat ttcttcttct ctatttattt
     2761 ctagggaaat agacttgata ttgtatccct catttacttt aacacaaatg gtcaattcct
     2821 catcaaattt taaagctcca aacggagcct taaaattttt atcccaagag ttatattcta
     2881 ttacactttg catttaatca caccctttta aaccaaatgt cttttgcata ctcagaaatt
     2941 gttctatcag aagaaaaaaa tccagagtta gctatattaa ctaaagacat tttattccat
     3001 ttttctttat ctctatataa cctgtttata tctgcttgag cttgaccata attttcaaaa
     3061 tctctcaata caaaatactc atcattgtaa gtagtgagtg aattataaat acttcttcct
     3121 tcttcgccaa gattaggaat aaatccattt attaaatcat ctactaccct ttttatatcc
     3181 atattagaat ggtataggtc aagtgaagaa tatccaccat atttattata atttagtact
     3241 tgttctgcac taagtccaaa taaaaacata ttttctttac caacctgttc acatatctct
     3301 acatttgcac cgtcaagtgt agccaaagtt atagcaccat tcatcataaa cttcatatta
     3361 cttgttccag atgcttcctt agttgtagtt gaaatttgct cactaacatt tgctgctggt
     3421 attattattt ctgctaatga tactccataa ttctctaaaa atactacttt taacttgtcc
     3481 tttactctaa catcattatt tatagtactt gcaacagaat ttataaattt aattatacat
     3541 ttagccaaat aatatcctgg tgctgctttt gcgccaaata taaaagttct tgggtcaaga
     3601 ttcaaattag gattatcaag taattcatga tacatatgaa gtacattaaa tatattcagt
     3661 aactgtcttt tatacgcatg caatctctta acttgaacat caaatatcga acttgggtct
     3721 acatttaaat cgtatttatc ttttataaac tttgctagat ttgctttatt attgtatttt
     3781 atatcatcaa gtctttgtaa aacagaggaa tcatttttaa atttttcaat attttttaat
     3841 tgtaatgtat ctttcttcca tgaatcacca attaaatctg taattaaatt gctaagttga
     3901 ggatttgaac ttataagcca tcgcctatgt gcaattccat tagtcttatt attaaattta
     3961 tttggttcat cttgatagaa atcttttaat acctctgttt caagaatatg agtatgaagc
     4021 ttagcaactc catttacact atgacttgtg acaatacata agtttgccat attgatattg
     4081 tcacagtcta ttatactcat tctttttatt ctatcttggt catatccttt attatttaat
     4141 tcctctacat atcttctatt tatttcttct attatcatat aaattcttgg taatagttct
     4201 ttcatcatac ttacaggcca tttttccatt gcttctgaca ttatagtatg attagtatag
     4261 gacactgttt ttttagttat ttcccatgct tcatcccaag ataaattttc ttcatcaagc
     4321 aaaattctca taagttctgg tatgcataag gtaggatgtg tatcatttat atgaattgct
     4381 accttatcga ataaattatt aatatttaat ttgttctttt tatattttct tattatatct
     4441 tgtatccctg cacttacaaa aaagtattct tgtttcaacc tcaacaactt acctgcatag
     4501 tttgaatcat caggatataa tacctgtgat atttcctcag tataatactt atgttttaaa
     4561 gcctcttcat agctaccaga ataatttaga gcatttgagg taagttcacc aaaatctctc
     4621 tttggtattt cactcttaaa caatcttaaa gtatttatac attggttttg gtatccgatt
     4681 attggtatat cataaggcat tgccattaca ggaaggtagt ttttatgaat tacttttaaa
     4741 tgactacctt ccttgattaa ttctacctca ccaccaaact tcaccattgt tgcttcattt
     4801 ggtcttacag tttcccatgc atatcgtcct tctgtaagcc agttatcagg cacttctacc
     4861 tgataaccat ttacaaattt ttgttcaaac agaccatatt tataccttat tccatatcct
     4921 tgaccactta tgttcaaaga tgccatagaa tctaaaaagc aagctgctaa tctaccaagt
     4981 ccaccatttc ctaaggctgg gtctacttca gcttcaatta aatcatccaa gttgattcct
     5041 aattcagata aaccttctct aacttcttct tcaatattta aatttaataa attagatttt
     5101 aactgtctcc ctattaaaaa ttctaaacta aaataataaa cttctttttt cttatctaac
     5161 tttgtagcaa cccatttttt tgctatctca tctttcaata gactacataa tacatttaac
     5221 aattgttcat cagtagcttc cttgatagat tgtgcatata agctatacat ttttacttca
     5281 aatttttgct tgaatttctt tttgcttatt gttaccaaaa aaaccactcc tttaatcaca
     5341 tatgtctcta tatgtttcta tatactcctt agctgatttt ttccaactat tatctgtttt
     5401 cattgcattt tcaactaatt taatccattt ttctttgtcc ttaaatactt tgattgcatt
     5461 tttcaaacag aaaaacatct catgagcatt gtaattttta aaactaaatc cattgccttc
     5521 tccagtaaat ttattataag gtgttactgt atctctaagc cctccagtct ctctaactat
     5581 tggtaaagaa ccatatctca tagctaacat ttgacctata ccacaaggct caaataatga
     5641 tggcattaag aacatatcac ttgcagcata tatctgttga gccaatgatg cattaaaagt
     5701 aattctagct gatactttat ctgaaaaatt agaatcgtaa tagttgaaca ttgattgata
     5761 ttgatgttct ccagttccta aaacgacaat ctgtaaatct tctctcataa gttctggcat
     5821 catgtatgct attaaatcaa atcctttttg agaaactaat ctcgaaacta tacctatcaa
     5881 cggaatagat gaatcttttt taagtcccaa tatatcttgt aatctcaatt tattttctac
     5941 ttttttgtca attgagtcta catcataatg aacaaatata tctttatctt ttgcagggtc
     6001 atttaaatca taatctatac catttaatat accttttaat tttcctgact cttttctaag
     6061 taatccatct aattgttcac cataaaaaga tgtttgtatt tcatttgcat aagtaggact
     6121 aacagttata attttatctg caaaatttat accagctttc ataaaattta ttgagccata
     6181 atactctata tctccattat caaagtattt ttgtggtaaa tccaatatat catataaaac
     6241 atgcttatca aatacacctt gatattggag attatgtata gtatacatag tttttatatt
     6301 tttatacccc tcaagggttg catatctttc ttttagaatt aatggtaaca tccctgtatg
     6361 ccaatcattt atatgtatta catctggata aaaatcaatt ctacttatag cttctaaaac
     6421 tgcatctgta aagaaagtat atctttctgc atcatctcca tatccataga tactctttct
     6481 ttcatcttct cttctaaaat aaaattcatt atctataaag taaaatttta caccatccaa
     6541 ttccatttct aaaagaccac agtattgatt tctccatcca acacgtacac taaacacagc
     6601 tatttctttt agttgatctt ttaaataact tggtatagtt gaatatttgg gcattattac
     6661 ccttacatct acaccttctt tttttaattc tttaggcaat gcataagaaa catctcctaa
     6721 tcctccagtt tttgcaaagg gccaacactc tgctgttaca taaaaaacct tcattagtca
     6781 ttcccccttc taaaaaattt atttatatat ttgtattctt ttccactaca agaggatatt
     6841 tttcatctcc tcttaattct ttcccatttg atacactcgt atttttatct aatattgcat
     6901 tatatagttt tgcatttgac tttattacac aattttgcat tactattgag ttctctataa
     6961 ctgttccttt ttcaacattt acctttctaa atatgatact atcttttaca gtaccttcta
     7021 ttaaacaacc agatgctata aagctatttt ctactttagc actatctgta taaattgtag
     7081 gtgattcatt cttttctttt gtaaatatct ttctttcaga atataataat tcatctgcaa
     7141 cttctaaatt taataaatct ttgctcattt caaaatatga ttcaacagaa tttacacatt
     7201 ttagatatcc tgtatattca taggctccta ttttcatgtt ttctgcttct tcaataataa
     7261 attcttctaa ataacaataa ttgcctttat ttacaatgtt atatatacat tcaacaaaat
     7321 cttcacgctt cataatatat gtctccatac atatgtttgc tctagggaac ttacctaaat
     7381 tatttcctac atttattacc ctattgttac tatctaaatt tagagttaag ttaccagcaa
     7441 aatctttatt tgcattattt acatttttat atattatagt tatatcatta tgagattttt
     7501 tatggtattc caatgcttga gaataattta aattgcatag catatagctt ggagctatta
     7561 aaatatattc ttcttcactc ttttctatat aatctagatt agctaagata gtatatatat
     7621 caccttctct atgtgagtaa gtatttctat acttagtgtt ttctggacta aaaattgata
     7681 ggccaccttt ttttctactt aaatcccaat ctttaccact acctatatgg tctgttaatg
     7741 atctgtattt ttcttttgcg aatattccaa ctttagtgat tcctgaattt atcatattag
     7801 ataaagcaaa gtctattatt ctatatcttc cagctattgg tgtagatgct attggtcttc
     7861 catagttaag tttgtttatt gctgggtctc cttttttgtt taaatttatt atccctaaac
     7921 attcatttct catcttaaag acctccttct attaatacgc atctaggttc gatattttca
     7981 tactcagaaa ctacatttat ttcattattt acattcttta tctgaacatt atcatttata
     8041 gttgcacact cacctatcat agctttttct atagttacat tttcacctat tacaacattt
     8101 ggcattatta ctgaatcaat tactttactt cctttaccaa caacaactcc atgtgataat
     8161 acagagttac ctacttcacc taaaattcta caaccatcag ctatcattga tctatgaaca
     8221 tttgcatttt tacctatata ttgtggaggc attgccatag tatttgtata tatcttccac
     8281 ttagggtctg ctaaatcaag tgtttctgga gattttatta tatccatatt agcatcccat
     8341 agactttgta tagttcctac atctctccag tatcctttaa atggataagc atacattcca
     8401 acattatctt ctaacatttt aggtattaaa ttttttccaa aatcatcata atttatttct
     8461 ggattttttt ctgcttcctt aaaataattt ctcaacattt tccaatcaaa tatgtatact
     8521 cccatagatg ccaaattgct cttaggttca cttggttttt cttcaaattc atagatactt
     8581 gaatcttcat ttgtattcat tatcccaaat cttgaagctt catcccaagg aacttcaatc
     8641 actgctattg tagctttaga gcctttttcc ttatgaaatt ttaacatttt gctataatcc
     8701 atcttgtata tatggtcacc agataatatc aatacatatt ctggattata ggtatctaca
     8761 aagtccatat tttgatatat cgcatgtgct gtaccattat accaatttcc ttctttttca
     8821 ttcataaatg gttgtaaaac atagacacca ccatttattc tgtccaaatc ccaatgactt
     8881 cccatgccta tatgtgaatt taatatcaac ggtctatatt gagttaaaac acctacagta
     8941 tcaataccag agtttgaaca attgcttaac acaaaatcta taattctata cttacctcca
     9001 aatgatacag ctggtttggc aattcttttt gtaaaaacac ctaatcttga accttgccct
     9061 cctgccaaaa tcatagctaa catctctttt ttcatttaat gacactcccc tcatctagta
     9121 attaatattt ataattgcat ttttactttt ataaacttta tcagtcaata aatgtcgtgt
     9181 ataaatgttg cttaaataat accttaataa aaataaaata atatcaacta tacaattgat
     9241 ataatgtata ccccataatg gacttaccga cgtatacatt attttccata agcactatag
     9301 tatttattaa tattcaatta tcggttaaaa aataatacaa attttatttt ataaatataa
     9361 aaacattttt tataaatctt ttgtgtcata taaacatgct tattttttaa tttgttaaat
     9421 tcgtaatagc aaaatataat ctaatatttg ttaaataatt atccaaagaa aatcaagt
//
LOCUS       DAMKNB010000112         9191 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.118, whole genome shotgun sequence.
ACCESSION   DAMKNB010000112 DAMKNB010000000
VERSION     DAMKNB010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 9191)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9191)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9191
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.118"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            393..1598
                     /locus_tag="PC494_003252"
     CDS             393..1598
                     /locus_tag="PC494_003252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HDF3913725.1"
                     /translation="MSKKVLIMSASTGGGHNRAALAIKEELTSKTLDGEPIECEIIDS
                     LKLVNNTMDKIISRGYEKSAIYTPKAYGSVYRLSETNLLSKNEFKDNLLITFMAKKFK
                     KLIRSEKPDLIIGTHPFPMIALSTLKKNFNLHNNESNAYTEHFYKHYTNTINVPPLIS
                     VLTDYTTHSTWIQNEIDYYIVGHEYVKELLVFDGVEPSKIRTFGIPVEKSFLSHRDKG
                     IVLSELNLSPDKLTVLLMGGSFGAGNIKETLDELLDTDRDFQILVITGKNESLKEKIE
                     KKLMSRYHDKNVCVLGYTDKMNDILASIDVLVSKPGGLTTTEALLKDVPMIVPYYIPG
                     QEEENLDFLSNCGAALRTTKKYNLSILLKVLIDDPSRLEMLKRNIKSIRKSNSAQNIA
                     NLILNIISG"
     gene            complement(1669..1890)
                     /locus_tag="PC494_003253"
     CDS             complement(1669..1890)
                     /locus_tag="PC494_003253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3913726.1"
                     /translation="MKPIMNLEEHNAMKEKRVKKMKSKDKPKYDDFEDISFSNKKKTK
                     KNVRNKNAEFRNNYKNYQYDYEEDFYEPI"
     gene            complement(2031..2630)
                     /gene="recR"
                     /locus_tag="PC494_003254"
     CDS             complement(2031..2630)
                     /gene="recR"
                     /locus_tag="PC494_003254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012634696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HDF3913727.1"
                     /translation="MQVYTGPITRLIEEFSKLPGVGRKTAQRLAFHIINMNTNDVEAL
                     SKAIIDAKREIRYCSICCNITDTDPCSMCSNKSRDSSVICVVEDPRDVAAMERTREFK
                     GQYHVLNGVISPMDGIGPDMLKIKELIQRLGNQEVKEIIMATNPTIEGEATAMYIARL
                     VKPMGIKVTRIAHGLPVGGDLEYADEVTISKALEGRREI"
     gene            complement(2643..2993)
                     /locus_tag="PC494_003255"
     CDS             complement(2643..2993)
                     /locus_tag="PC494_003255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HDF3913728.1"
                     /translation="MAKKGFGGGMMPGGGNMNNLLKQAQKMQENMQKAQQELESKEVE
                     ASVGGGAVTVKVNGKKEVIDITIKPEVVDPDDIEMLQDLVLSAVNQALRNIDDIQASQ
                     MSKVTGGMNIPGLF"
     gene            complement(3052..4689)
                     /gene="dnaX"
                     /locus_tag="PC494_003256"
     CDS             complement(3052..4689)
                     /gene="dnaX"
                     /locus_tag="PC494_003256"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HDF3913729.1"
                     /translation="MHKALYRAYRPQKFEDVIGQDHIIKTLKNQIYSDNIGHAYLFCG
                     TRGTGKTSTAKIFSRAVNCLNKINEEPCNECEICESVLKDNTMDVVEIDAASNNSVDD
                     IRELRESVKYSPANAKYKVYIIDEVHMLSQGAFNALLKTLEEPPSYVIFILATTEPHK
                     IPATILSRCQRYDFKRVTVKDMTLRMKKICEDEGIDIDDKALNLIARNSQGALRDALS
                     ILDQCMSFGESKIDYKDVVELMGSVNIEQLFELSQCIVEQDTKKSLEILNEFVLWGKD
                     IRNLINDLIDHFRNLMVCKVSSELDEIISLPEETIEQLKIQSKNIDINDLIRILNILS
                     ITQDDIKSSSNPRVLVEITIMKIAQPMFDESKEALIKRVENLEKMIELGNFKSEKIGN
                     NKEKEYEVDREIDVKQENVVYEDVKNEDVILIESSWKNILKQIKKDKKMPIYALLSEV
                     KSFNVYSNMLYVIFDDKFDFAKTRLSSQDTINYLEKTIRDVLNRSFNVKIVLTSEVKD
                     INLEVKEKKDIGEEILKNIVSEEILEIKDSIDENESK"
     gene            complement(4766..5030)
                     /gene="ffs"
                     /locus_tag="PC494_003257"
     ncRNA           complement(4766..5030)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="PC494_003257"
                     /product="signal recognition particle sRNA large type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01854"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF01854"
     gene            complement(5068..5159)
                     /locus_tag="PC494_003258"
     tRNA            complement(5068..5159)
                     /locus_tag="PC494_003258"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(5123..5125),aa:Ser,seq:gga)
     gene            complement(5160..5615)
                     /locus_tag="PC494_003259"
     CDS             complement(5160..5615)
                     /locus_tag="PC494_003259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deaminase"
                     /protein_id="HDF3913730.1"
                     /translation="MESSFYMKEALKEAYKAYNKKETPIGAIIVKDNQIIARAHNLTE
                     TLKDSTAHAEILAIKQASEKLGGWRLTDCDLYVTMEPCIMCSGAIVNSRIKKLIIGTR
                     HVKNSYIEKQHEFKLDYFNNNNVKAAFDVLQEECSIILQEFFKALRKRD"
     gene            complement(5936..7207)
                     /gene="serS"
                     /locus_tag="PC494_003260"
     CDS             complement(5936..7207)
                     /gene="serS"
                     /locus_tag="PC494_003260"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000884181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HDF3913731.1"
                     /translation="MLDIKRIRENLDDIKKAMERRGEREFDLDAVVELDNKRREILQE
                     VEVMKNELNVNSKKIPQLIKEGKDVTEEKARLKELSDKIKGIDEKVKEVEAKMEYTLM
                     RIPNVPHPEVPQGETDEDNVQIRTWGEPTKFDFEHKAHWDIGTGLGILDFERAGKITG
                     SRFTLYRGLGARLERSLMNFFLNTHTAKHGYTEVLPPFMANRNSFIGTGQLPKFEEDM
                     FKIEGLEYFLIPTAEVPVTNIHANEILDVAELPIKYCAYTPCFRSEAGSAGRDTRGLV
                     RQHQFNKVELVKFVKPEDSYNELESLTHDAETMLQMLGLPYRVVKICTGDLGFTAAFK
                     YDLEVWMPSYNRYVEISSCSNFEDFQARRAGIRFKRDKKSKAEYVHTLNGSGLAIGRC
                     LAAILENYQQADGSVVVPEELRPYMGVDVIK"
     misc_binding    complement(7333..7538)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(7666..8547)
                     /locus_tag="PC494_003261"
     CDS             complement(7666..8547)
                     /locus_tag="PC494_003261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel"
                     /protein_id="HDF3913732.1"
                     /translation="MNFLSLAKTASTNSNITKRTLENMLDNFSDNIPNIIYAIIVFVI
                     GIYISKIVRRMVSKFLIKYGMSKGVNNFIVYGIYISMLSIISLISLGIIGIQTTSVVA
                     VLGAAGFSIGLAFKEILSNLGSGMIILFFKPFNIGDYIQGSGVEGTVSDIQIFSTVLK
                     TPDNKTIIIPNFQLTSNNIINYTHQNKRRIDFSYNISYDSDIDVVKSILNEIFTNEKR
                     ILNDPKPIIGLNSIGNNTMQIVARPWVKTDDYWDVYFDVMEKVKNKFDENDIKVPFVP
                     SSLLFNNTGNLNTMDKR"
     gene            complement(8559..9068)
                     /locus_tag="PC494_003262"
     CDS             complement(8559..9068)
                     /locus_tag="PC494_003262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HDF3913733.1"
                     /translation="MNSNERRSKLIDILKESKHPVKGGTLAELLNVSRQVIVQDIALI
                     RARGFEIIATPQGYIIYNQPYFTKQIKCKNHKDSKEIYDELKIIVDLGGIIKDVIVNH
                     PTYGQITAELNIYSKMDIDNFMKKVETNEFKQLSVLTECSHIHTIEAIKEETIEAIVK
                     ELKDNGILS"
BASE COUNT         2942 a         1598 c          974 g         3677 t
ORIGIN      
        1 ttcctttttt caaggacaag taatactata tcatctttat ctattctagt caatataatt
       61 ttttactttt tttatttttt ttatttatca tgtattcttt atatttaatt tttaaaactt
      121 aatgctaagt aaacctgttt atttcataaa actaatatat attctatgct ctattttcct
      181 ttttattcta tatttaaatt ttttatttac aagaatattt ttaatataac atatttgata
      241 aaattaattt acatttcttt cacttgtaat ttttgcaatc ttgtattaga ttaatattaa
      301 aaataattta tcaataacct tattcacaaa gacagttttt atatatcaaa atataatata
      361 aatactatgc tacattttag gaggatttta ttatgagcaa aaaagtatta ataatgtctg
      421 cttccactgg tggtgggcat aatagggctg ctctagctat taaagaagaa cttacttcca
      481 aaacacttga tggagagcca attgaatgtg aaataataga tagtttgaaa ttagttaata
      541 atacaatgga taaaataatt tcaagaggat acgaaaaatc tgctatatat actcccaaag
      601 cctatggaag tgtatataga ttatctgaaa caaatctttt atcaaaaaat gaatttaaag
      661 ataatctact aataacattc atggctaaaa aatttaaaaa acttattaga agcgaaaaac
      721 cagacttgat tataggaacg catccttttc caatgattgc tctaagtaca ttgaaaaaaa
      781 actttaattt acataataat gaatcaaatg cttacacaga gcatttttat aaacattata
      841 caaataccat taatgttcct ccgcttattt ctgtattaac cgattatact actcattcta
      901 catggataca aaatgaaatt gattactata ttgttggtca tgaatatgta aaagaattat
      961 tggtgtttga tggagttgaa ccgagtaaaa ttagaacatt tggaatccct gttgaaaaat
     1021 cttttctctc tcacagagat aaaggtattg ttctttctga gttgaattta tctcctgata
     1081 aattaactgt tttacttatg gggggtagct ttggggctgg aaatataaaa gagacacttg
     1141 atgaattact ggatactgat agagactttc aaatacttgt aattactggt aagaatgaaa
     1201 gcctaaaaga aaaaatcgaa aaaaaactta tgtctcgtta tcatgataaa aatgtatgtg
     1261 ttcttggata cactgataag atgaatgata ttttagcttc tatagatgta ttagtaagca
     1321 aacctggtgg acttactaca actgaggctc ttttaaaaga tgtacctatg atagttcctt
     1381 attatatacc aggtcaggaa gaagagaatc ttgatttctt atctaattgt ggtgcagcac
     1441 ttagaactac aaaaaaatat aacttgtcaa tattactaaa agttttaata gatgacccta
     1501 gcagattaga aatgctaaaa agaaatatta aatcaataag aaagtcaaat tcagcccaaa
     1561 atatagctaa tttaatttta aatataattt ctggttgata aaataaataa aatccctata
     1621 gtatatatat tatctattag ggatttttta ttttctaatt atttaatatt aaattggttc
     1681 ataaaagtct tcttcataat catactgata atttttataa ttatttctaa attcagcatt
     1741 tttatttcgt acattttttt tagttttttt cttattagaa aaacttatat cctcaaaatc
     1801 atcatattta ggtttatctt ttgatttcat ttttttaact cttttttctt tcattgcatt
     1861 atgttcttct aagttcataa ttggtttcat gttgcacccc tatcaaaatt tttaaatgat
     1921 ttatacaaca aattatacaa tacagaagaa atttattcaa taaatctaaa tcaaaattaa
     1981 tttgaattta actcaaaaaa ttacaaaaat cgaggtatta acctcgattt ttatatttct
     2041 cttctgcctt ctagtgcttt tgatattgtg acctcatctg catactctaa atcgcctcca
     2101 acaggaagac catgagctat ccgagtgact ttgattccca ttggttttac taacctagca
     2161 atatacatgg ctgtagcttc accttcaata gtaggatttg ttgccattat tatttctttg
     2221 acttcctgat tgccaagtct ttggataagt tcctttattt ttaacatatc tggtccaatt
     2281 ccatccattg gagaaattac tccatttaat acatggtact gtcctttaaa ctctctcgtt
     2341 ctctccatag ctgctacatc tcttggatct tccacaacac atataacact tgaatctcta
     2401 cttttatttg aacacatgct acatgggtct gtatctgtta tattacaaca aattgagcaa
     2461 tatcttattt ctctttttgc atctataatc gctttagata aagcttccac atcattagta
     2521 ttcatattaa taatatgaaa agccaatctt tgagcagtct ttcttcctac tccaggaagc
     2581 tttgaaaatt cctctataag tctcgttatg ggacctgtat aaacttgcat aaataccacc
     2641 tactagaata acccaggtat attcatacct ccagttacct tactcatttg acttgcttgt
     2701 atatcatcaa tatttctcaa tgcttgattt actgcactta aaactaaatc ttgtagcatt
     2761 tctatatcat ctggatcaac tacttctggc ttgatagtta tatctataac ttctttttta
     2821 ccattaactt ttacagtaac tgctcctcca ccaactgaag cttctacttc tttactttct
     2881 aactcttgtt gagctttttg catattttct tgcatttttt gagcctgctt taacaagttg
     2941 ttcatatttc caccaccagg catcattccg cctccaaaac cttttttagc cataaacact
     3001 attcctccta aacttatttt cattttatta ttatatcata atagtatttt attatttact
     3061 ctcattttca tcaatactat cttttatttc taatatctct tcactcacta tgttctttaa
     3121 tatttcctca ccaatgtcct ttttctcttt aacttcaaga tttatatctt taacttctga
     3181 tgtcagtact atttttacat taaaacttct atttaaaaca tctcttattg ttttttctaa
     3241 ataatttatt gtatcttgag agctcagtct agtttttgca aaatcaaatt tatcatcaaa
     3301 tataacatac aacatattag aatatacatt aaaacttttt acttcactta agagtgcgta
     3361 tattggcatt tttttatctt ttttaatttg tttaagtata ttcttccaag atgactctat
     3421 aagtataacg tcctcatttt ttacatcttc ataaactaca ttttcttgtt ttacatctat
     3481 ttctctatcg acctcatact ctttttcttt attattccca attttttcag acttaaagtt
     3541 ccccagttca atcatttttt ctaagttctc aactcttttt ataagagctt ctttactttc
     3601 atcaaacatt ggttgagcaa ttttcattat ggttatttcc actaaaaccc ttggatttga
     3661 agatgacttt atatcatcct gagttattga taatatattt aaaatcctta ttaaatcatt
     3721 tatatctata tttttagact gaattttaag ttgttctata gtttcttctg gtaatgaaat
     3781 tatttcatcc aattctgatg aaaccttaca taccattaaa tttctaaaat gatcaattaa
     3841 gtcatttata agatttctta tatctttgcc ccataagaca aattcattta atatctcaag
     3901 agacttttta gtgtcctgct ctactataca ttgagacaat tcaaataatt gttctatatt
     3961 tacgcttccc attaattcaa caacatcttt ataatctatc ttactttctc caaaagacat
     4021 acattggtct aatatactaa gtgcatctct aagagctcct tgagaatttc tagctattaa
     4081 attaagagct ttatcatcta tatcaattcc ttcatcttca caaatctttt tcattctaag
     4141 ggtcatatct ttaactgtaa ctcttttaaa atcgtatctt tggcatcttg ataaaatggt
     4201 tgcaggtatt ttgtgaggct ctgtagttgc taatataaaa attacatatg atggaggttc
     4261 ctctaaggtc tttaataatg cattaaaagc tccttgagac aacatatgaa cttcatctat
     4321 tatatatact ttatatttag cattggctgg agaatatttc acactttctc taagctctct
     4381 tatatcatct acactattat ttgaagctgc atctatttct acaacatcca ttgtattatc
     4441 ttttaataca gattcgcata tctcacactc attacacggt tcttcattta ttttattcaa
     4501 acagtttact gctcttgaaa aaatctttgc agtagatgtt ttaccagtac ctcttgttcc
     4561 acaaaacaaa taagcatgtc ctatattatc actatatatt tgattcttta aagtcttaat
     4621 aatatgatct tgaccaataa catcttcaaa tttttgtggt ctatatgctc tatataatgc
     4681 tttatgcatc tttttacctc tctttagcaa aattaataaa aaaatccctc attatctaag
     4741 ggattagtct tttatatatt aaatgctgta caccatctat cgacttaatt ccataggcgt
     4801 taccaaaaca gttagctcaa cttaggcacc cccacggcac acaaaagtga tcacttaccg
     4861 ctgcttcctt ccggatctga cggggttcat gagctttcat tgcgcaggac ctaagcatca
     4921 acaccactta tttagggcgg ccctacagaa aataagcctt tagatggaat tcaatcctgc
     4981 tatagcggat tgcaggttac agggcaccgc tacctcccca tctagtacag caaaattaca
     5041 accatattta attactttca ttgtttctgg cggagagagt gggatttgaa cccacgatac
     5101 agttttaccc atatactcgc tttccaggcg agcgccttcg accactcgac catctctcct
     5161 taatctcttt ttctcaatgc cttaaaaaat tcttgcaata tgatcgagca ttcttcttgc
     5221 aaaacatcaa aagctgcttt tacattatta ttattaaaat aatctaattt aaactcatgc
     5281 tgtttttcta tatatgaatt ttttacatgt cttgtcccta ttataagctt ttttattcta
     5341 gaattaacta ttgcgccact acacattatg caaggttcca ttgtaacata taaatcacaa
     5401 tcagtcaacc tccaaccacc taatttttct gatgcttgtt ttatcgctaa aatttctgca
     5461 tgtgccgtag agtcttttaa cgtttctgta aggttatgag ctctagctat tatttgatta
     5521 tctttaacta taatagcacc tattggtgtt tcttttttat tatatgcttt atatgcttct
     5581 tttaatgctt ctttcatata aaatgaactt tccataattc ctcccaaaac ttataacaaa
     5641 cttatcttat cataattcat tttataattc aacttaattt tattttgttt atttaattat
     5701 tactatatat agctatattt ttttaaaatt agttctaaaa taatttttag atattcatac
     5761 aagagtgttt tataaaaata tttagtgttt tatgatgaaa attctgctgt gtaaattaac
     5821 ataaaaaaac tatgaaatta atatttataa taatttcata gtttttttat ttattgttta
     5881 ctcataatat attctcttca tcaaagcata ctctatatat acaattaata taaatttatt
     5941 ttataacatc aacacccata taaggtctta attcttctgg aactactaca gaaccatctg
     6001 cctgctgata attttctaat atagcagcca aacatcttcc tattgctaat ccagaaccat
     6061 ttaatgtatg aacatattct gcttttgatt ttttatctct tttaaatctt attcctgctc
     6121 ttcttgcttg gaaatcttca aaatttgaac aagaagatat ttctacatat ctattgtaac
     6181 ttggcatcca aacttctaaa tcatatttaa atgcagctgt aaatcccaaa tctcctgtac
     6241 atatttttac aactctatat ggaagaccta acatttgtaa catagtttca gcatcatgag
     6301 ttaatgattc taattcatta taagaatctt ctggtttaac aaatttaact aattcaactt
     6361 tattaaattg atgttgtcta actaaacctc ttgtatctct tcctgctgaa cctgcttcag
     6421 atctaaaaca aggagtatat gcacagtatt taattggaag ctctgcaaca tctaatattt
     6481 cattagcatg tatattagta acaggaactt cagctgttgg tattaagaaa tactctaatc
     6541 cttctatttt aaacatatct tcttcaaatt taggaagttg accagtccct ataaaactat
     6601 ttctattggc cataaatgga ggtaagactt ccgtatagcc atgcttagct gtatgagtat
     6661 ttaaaaagaa attcattaaa gatctttcta atctagctcc taatccccta tataaagtaa
     6721 accttgaccc agttattttc cctgctcttt caaaatctaa aatacctaga cctgtaccta
     6781 tatcccaatg cgctttatgc tcaaaatcaa atttagtagg ttctccccaa gttcttattt
     6841 gaacattgtc ttcatctgtt tcaccttgtg gtacctctgg atgaggaaca tttggtattc
     6901 tcattaatgt atattccatt tttgcttcta cttcttttac tttctcatca atacctttta
     6961 tcttatctga taactctttc aatcttgcct tttcttctgt tacatctttt ccttctttta
     7021 ttaattgagg tattttttta gaatttacat ttaactcatt tttcataact tcaacttctt
     7081 gaagtatttc tcttctttta ttatctaatt ccactacagc atcaaggtca aattctcttt
     7141 cacctcttct ttccatagct tttttgatat catctagatt ttctcttatt cttttaatat
     7201 ctaacatatt aattcctcct aataattttg ataatataag ttataattcc aacttaattt
     7261 acaaacatta tacttgtaaa ctcttagttt aaacaaattt taaaaataaa aaaagacctc
     7321 cgtttaccct ataaaaggga cgaaaatctt ttatccgcgt tgccacccta attgactata
     7381 ctaaaatgta taatcctctc agacctataa cgtaggtaaa cgtctagctt taactagaag
     7441 ctctagagta gattcaaaaa ccattgtaat gagttttcac catccactca ttctctgaat
     7501 acaatctgtt ttttactatt ttccttcaca gctttttaac taattgtttt atttgataat
     7561 cattatatta tatatattaa catctttcaa tactattatt caaatttttt tagaattttc
     7621 tttaattttt tatattaaat tcattttttc tatttaatta aaaccttatc ttttatccat
     7681 tgtatttaga ttacctgtat tattaaataa taatgaagaa ggaacaaatg gaacttttat
     7741 atcattctca tcaaatttat tttttacctt ttccattaca tcaaaatata catcccagta
     7801 atcatcagtt tttacccaag gtctagcaac tatttgcatg gtgttatttc ctatagagtt
     7861 taaacctatt ataggctttg gatcatttaa tattcttttt tcgtttgtaa aaatttcatt
     7921 taatatagac ttaactacat ctatatcact atcatatgaa atattatatg aaaaatctat
     7981 tcttcttttg ttttgatgtg tgtaattaat tatattatta cttgtcagtt gaaaattagg
     8041 tataattata gttttattat ctggcgtctt aagaacagtg ctaaatattt gtatgtcaga
     8101 aactgtacct tctacacctg aaccttgaat ataatcacct atattaaatg gcttaaaaaa
     8161 taaaataatc ataccagagc ctaaatttga taatatttct ttaaaagcta aacctatact
     8221 aaatccagca gctcctaaca cagctacaac tgatgtagtt tgtatcccta taatacctaa
     8281 gcttatcaat gatataatag ataacataga tatatatatt ccatatacaa taaaattatt
     8341 tacaccttta ctcattccat atttgattag aaactttgaa accatccttc ttactatttt
     8401 agatatataa atacctatca caaatacaat tattgcatat ataatatttg gtatattatc
     8461 actaaaatta tcgagcatat tttctaaagt tctcttagtt atattgctat ttgttgaggc
     8521 agtcttagcc aatgataaaa aattcattca actcctcctt atgataatat tccgttgtcc
     8581 tttaactctt ttactatagc ttctatagtt tcttctttta ttgcctcaat tgtatgaata
     8641 tggctacatt ctgtcagaac cgataattgt ttaaattcat ttgtctcaac tttcttcata
     8701 aagttgtcta tatccatttt agaataaata ttaagttctg cagttatctg accatatgtt
     8761 ggatgattta cgatgacatc ttttataata ccacctaaat ccacaattat ctttaattca
     8821 tcataaattt ctttagaatc cttatgattt ttacacttta tttgttttgt aaaatacggt
     8881 tgattatata ttatatatcc ttgaggtgta gctattattt caaatcctct agctcttata
     8941 agggctatat cttgaactat tacttgccta cttacattta atagttcagc tagtgttcca
     9001 ccttttacag gatgcttaga ttcttttaaa atatctatta atttacttct tctttcatta
     9061 gaattcatat tacaccttct ttccaaataa aaactttacc tatactatat aattttatat
     9121 tttatcttat tataaatcaa tattgacttt atattctatt taatcttaac ttttataata
     9181 aataaaaaag a
//
LOCUS       DAMKNB010000113         8992 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.119, whole genome shotgun sequence.
ACCESSION   DAMKNB010000113 DAMKNB010000000
VERSION     DAMKNB010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8992)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8992)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8992
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.119"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            complement(81..689)
                     /locus_tag="PC494_003263"
     CDS             complement(81..689)
                     /locus_tag="PC494_003263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase"
                     /protein_id="HDF3913734.1"
                     /translation="MEKDFFRKNGIDLAKSILGKYLIRKYENKVIVTKIIETEAYMGV
                     NDKGAHVYGNKKTDRTKPLYLDGGHIYVYLIYGMYNCLNLSANIENVPECVLIRGVEP
                     ITSLDEISMNRYNKAYTELSKYQVKNITNGPGKLCKALKIDRSLNSKSIMGEELYISD
                     FYYDDKGKKVFSKDELDIKTSKRINIDYAEEAKDFLWRFYIE"
     gene            complement(798..3536)
                     /locus_tag="PC494_003264"
     CDS             complement(798..3536)
                     /locus_tag="PC494_003264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PAS domain-containing sensor histidine kinase"
                     /protein_id="HDF3913735.1"
                     /translation="MESKGTLSKNKVYILANGLFLVIALLNINLYTVSINMYRIILLW
                     IFGYSIVYISSFKTDEFINILKVGCLVLVFVSILGVVNLKIQKFQIVLLNLSIINMST
                     FIYLTISKVKKLRISPILIFYSAFVILDYFIRNIFSDINWNMIIILINICISMFNLLY
                     LLNKLDSNIEHYKLIKDLTYFVFFTTIICFVAISKINIVDSDRLIGVIYLLLCNHTYY
                     VYVYSLNNRVVYPYYELDSINKKLSKKSEQLGKINLAIEKDMIIQRTLKNYIDQRKEL
                     LRQALDTIPNVWIVTDYDFNISYTNNKFKDEFSKDMNNYYKILTFIKEDEKVAEKLKK
                     FDNDISIIDKLVELNDKIYLLSLSNNKDESNYLISLNDITNEIKIDEEIRNINKDYEN
                     IILNIPSPILVRSAEGGIKKNKVISINKKYEKSFKCVSSDLVDMTLEQYFETFNIDFF
                     DNREFKRLNLTQEKKAEIVSYNDTANCIVNFVMSDSEGEEHVEEVRVGDYWSDNKLFK
                     LLTFRDITKEINILRTVNEQKIIYEKLLDVIPEAIFLEDLSTSRVLYTNRAFRELFGI
                     SSDVLGVTTQKYRNILVKKYINNLNIGEREKSIHIVNENNHIKEVKMISRTLYFGQKR
                     SRVRIIKDLSVQRESERLKKALIKQRQYDQMKMEFYANISHELKTPLNNIYSSVQLIE
                     NLYKKGKIIDFQDILKEHIKITKQNMFRLLRLIDNIINISQVKSDIYKIKAVNFDIID
                     ITERIVTSISSYAKSKGIDLIFDTDEETVMVGLDPESIERIILNILSNAIKFTLEGGE
                     ILVGIYKKDETVEIIIKDTGVGIDKEKLKDIFNRFKQIENSGISNEFGSGIGLCLTKS
                     LIEIQNGKIYIDSKVGEGTNVKVIFPIKEVVEEVYDNSNYNDNIEKFEIEFFDIYK"
     gene            complement(3684..4475)
                     /locus_tag="PC494_003265"
     CDS             complement(3684..4475)
                     /locus_tag="PC494_003265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011987989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HDF3913736.1"
                     /translation="MKLKKLLSVALVSAIAISAVGCSNKEDKKILVGASSNPHAKILE
                     VAKPLLKEKGYDLEVKIFDDYVLPNTALDEGSLDANFFQHIPFLEETVKEKGYKLTYT
                     SKVHIEPMGFYSEKVKSLDELKDGAVIAVPNDATNGARALKLLAKNKLIEVKDGELIT
                     KKDITKNPKNIVIKEMNAEQLPTVLKDVDGAVINSNYALTANLNPTKDAIVIESSDSP
                     YVNIIACRENNKDSDKIKALSEAMNSKEVKKFIQDEYKGSIVPAF"
     gene            complement(4511..5167)
                     /locus_tag="PC494_003266"
     CDS             complement(4511..5167)
                     /locus_tag="PC494_003266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF3913737.1"
                     /translation="MNSLIDFLTTLFPNALLQTLYMVIVPTIVATILGFILAIILVVT
                     KPDGLKPNSTINSALGFIVNIFRSFPFMILIVAMIPITRLIVGTSIGETAAIVPITIG
                     AAPFIARIIESSLNEVDKGLIEAAKSFGATKRQIVFKVMIKEAMPSIVSGITLSIISI
                     LGYTAMAGAVGAGGLGNIALIYGYQRFDTAVMVYTVIALIILVQIIQGVGNLAYKKLK
                     "
     gene            complement(5160..6125)
                     /locus_tag="PC494_003267"
     CDS             complement(5160..6125)
                     /locus_tag="PC494_003267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HDF3913738.1"
                     /translation="MISIKNVNKYYGKIQVLKDVSIEIESGEIFGIIGHSGAGKSTLL
                     RCINGLEEYQEGSVLVSDKEVKSLNEKQMRDLRKELGMIFQHFSLLERKTVFDNVALP
                     LECFGYSKAEIKKRVLELLEVVGISEKKNDKPRNLSGGQKQRVAIARALALNPQVLLC
                     DEATSALDPNTTKSILSLLEDINKKLGITIIVVTHQMEVIKQICGRVAIMENGEVLEV
                     GDTEEIFLRNTKGLRKLIGEESIILPKGTNIKILFPKDISNEAIITTMARELNIDVSI
                     IFGKLEQFKDDILGSLIINISDKSGEQVKQYLTSKGIRWEEMINE"
     regulatory      complement(6231..6337)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00162"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="SAM riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF00162"
     gene            complement(6627..7571)
                     /locus_tag="PC494_003268"
     CDS             complement(6627..7571)
                     /locus_tag="PC494_003268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YafY family transcriptional regulator"
                     /protein_id="HDF3913739.1"
                     /translation="MSRAERLIELMITINAKRSFTAGELAEEFSVSKRTILRDLQVLE
                     SIGFPLYSKVGAAGGYHVLKERILPPIAFSESEVKSIFFAYQSLEYYNDLPFEQETIS
                     VLKKFLNCIPNDIQYNIENIRRKFVFWTPDRHCSTPLLKELFNIVMNEFTIKIEYSSK
                     QKNSVRTIVPIGLYAMNGLWYCPAYCIKSESIKEFRVDRIVKILSIENLSSKKYKVLS
                     SIHDYLKNMEVGTDYHIKINLTDEGVKRCETEFLLARGLKILSKGGYIDMYIPKSTLN
                     WVAEYFLTFGKNATIIEPIELKHLIKSKVLELYNHHCI"
     gene            7682..8149
                     /locus_tag="PC494_003269"
     CDS             7682..8149
                     /locus_tag="PC494_003269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3913740.1"
                     /translation="MENDTIKADDILNYCLSNLDDVVLMDSWGERAIYYNPNGVLKRG
                     VYVLTIKEKDSNNDKGSLVSRPNVYRVNIGLKKETFIEMFGYIPKRPGVGQIVDMDFD
                     FTKLDTIMPHPIYSWMGWICVLSPTEKTFENFKTLIGESYNFAKQKFKKRKNK"
     gene            complement(8319..8918)
                     /locus_tag="PC494_003270"
     CDS             complement(8319..8918)
                     /locus_tag="PC494_003270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3913741.1"
                     /translation="MKLKRTLFVGLALVLAIGITACTKNNEKPSENTGKNPNESVNNN
                     EGYMNYYSTSYNDYIAGLNRYSIYDTPESINNQFKDKEYPGNEKYLSDVKAAYKDSRD
                     KIQSFVTSLKKDGKTEDTELKKMNDDLIAEGERLVKDIDKRIEKLDKVSDEDMKKGQN
                     DFIKLVHGTEDVGNDIGSGFRKMIKDMNDRLGITGNNKK"
BASE COUNT         2916 a         1491 c          875 g         3710 t
ORIGIN      
        1 aactaaaaat tctataaaaa aataagatac atacctataa aataccttcc tatagataca
       61 tatcttacct atataaaaac ttattctata taaaaacgcc ataaaaaatc ttttgcttct
      121 tctgcataat ctatatttat acgtttacta gtttttatat ctaactcatc tttactaaat
      181 actttttttc ctttatcatc ataataaaaa tcacttatat ataattcttc acccattata
      241 ctcttactat ttagacttct atctattttt aaagctttgc aaagttttcc tggtccgtta
      301 gtaatatttt ttacttgata tttactcaac tcagtgtaag ctttgttgta tctattcata
      361 gatatctcat ctaaagaagt tataggctct acccctctta ttaatacaca ctctggcaca
      421 ttttctatat ttgcagataa attcaagcaa ttatacatac cataaattaa ataaacatat
      481 atatgtccac catctaaata taatggctta gttctatctg tctttttatt gccatataca
      541 tgtgctcctt tatcatttac acccatgtat gcttctgtct ctatgatttt ggtaacaatt
      601 actttatttt catatttcct tattagatat ttacctaata ttgatttggc taaatcaatt
      661 ccattttttc taaaaaaatc cttttccaaa atttcacctc ataaaattta tttaaaacgc
      721 atcaaataca actaaagtaa taaataaaat taactcttat taatgtgata tatataaaca
      781 ataaatttag acatttatta tttatatata tcaaaaaatt ctatctcaaa cttttcaata
      841 ttatcattgt aatttgaatt atcatatact tcttcaacaa cctctttaat tgggaatata
      901 acttttacat tagttccttc tcctacctta ctatctatgt aaatcttccc attttgaatt
      961 tcaatcaatg attttgtaag gcataaacct ataccacttc caaattcatt tgatatacca
     1021 ctgttttcaa tttgtttaaa tcgattaaat atatccttta atttttcttt gtctatgccc
     1081 actccagtat cttttataat tatctctact gtttcgtctt ttttatatat acctacaagg
     1141 atttctcctc cttctaaagt aaattttata gcatttgata atatatttag tattattctt
     1201 tctatcgatt ctgggtcaag ccctaccata acagtttctt catctgtatc aaaaattaaa
     1261 tctattcctt tagacttagc ataactacta atagatgtaa ctattctttc tgttatgtca
     1321 ataatatcaa aattaactgc tttaatctta tatatgtctg acttaacttg agaaatattt
     1381 attatattat ctattaatct caataatcta aacatatttt gtttagttat ttttatatgt
     1441 tcttttagta tatcctgaaa atcaattatt tttccttttt tataaaggtt ttcaataagt
     1501 tgaactgaac tatatatatt atttaaaggt gtcttaagtt catgagatat attagcataa
     1561 aactccatct tcatttggtc atactgtctt tgttttatta atgctttttt aagtctttca
     1621 gactctcttt gcacacttaa atctttaata attctcactc tacttctttt ctgtccaaag
     1681 tataatgttc ttgatatcat ttttacttct ttaatgtgat tattttcatt tactatatgg
     1741 atactcttct ctctttctcc tatatttaaa ttgtttatgt atttttttac taatatattt
     1801 ctatattttt gtgttgtaac tcctaataca tcactagaaa ttccgaacaa ctctctaaag
     1861 gctctatttg tatatagtac tcttgatgta cttaaatcct caagaaaaat agcctctggt
     1921 ataacatcca gtaatttttc atatattatt ttttgttcat ttactgttct aagaatattt
     1981 atctctttag ttatatctct aaatgtaagc aatttaaaga gtttattatc tgaccaatag
     2041 tctccaactc taacttcttc aacatgttct tcaccttctg agtcagacat cacaaaatta
     2101 actatacagt ttgctgtgtc attgtaactt actatttcag ctttcttttc ttgtgttaga
     2161 tttaatcttt taaattccct attgtcaaag aaatctatgt taaaagtttc aaaatattgt
     2221 tctaatgtca tatcgactaa atcacttgaa acacatttaa aactcttttc atatttttta
     2281 tttatactta ttaccttatt cttctttatg ccaccttcag cacttcttac aagtatagga
     2341 gatggaatat ttagtataat gttttcatag tctttattta tatttcttat ttcttcatct
     2401 attttgattt catttgtaat atcatttaaa cttattaagt aattgctttc gtctttatta
     2461 ttacttaaac ttaacaaata aattttatca tttaactcta ccagtttatc aattatactt
     2521 atatcgttat caaatttctt caatttttca gcaacttttt catcttcctt tataaaagtt
     2581 aatattttat aataattatt catatccttt gaaaattcat ctttaaattt attatttgtg
     2641 taacttatat taaaatcata gtctgttact atccatacat ttggtattgt atccagagct
     2701 tgtctaagta attcttttct ctggtctatg tagtttttta atgttctttg tataatcata
     2761 tccttttcta ttgctaaatt tatctttcct aattgctctg actttttact taatttttta
     2821 ttgattgaat caagttcata atatggatac actactctat tattaagact gtatacatat
     2881 acataataag tatggttaca taatagtaaa tatattactc ctattaatct atctgaatct
     2941 actatattaa tcttagaaat tgctacaaaa catataatag ttgtaaaaaa aacaaaatat
     3001 gttaaatctt ttattaactt atagtgctca atgttactat caagtttatt caacaaatat
     3061 agtaaattaa acatagatat acaaatatta attaatataa taatcatatt ccagttaata
     3121 tcactaaaaa tatttcttat aaagtaatct aatatcacaa aagcactata aaaaattagt
     3181 attgggctta ttcttagttt ttttacttta gaaatggtta agtatataaa agtagacata
     3241 ttaattatgc ttaagttaag caatacaatt tggaattttt gaatttttaa atttactact
     3301 cctaaaatac ttacaaaaac taatacaaga caccctactt tcaatatatt tataaattca
     3361 tctgttttaa agctacttat ataaactata gaatatccaa atatccaaag taaaattatt
     3421 ctatacatat ttatagaaac tgtatacaaa tttatattta aaagtgcaat aaccaaaaat
     3481 aacccattag ctagtatata gaccttattc ttacttaaag ttcctttaga ttccatattc
     3541 cccaccactt cttcattttt atatagtttt acctataaat atgttaccac aattcttcca
     3601 aaaaatttgt cactttctag ttataaaaaa aaatgagtaa atatttttaa ttttactcat
     3661 tttgtagatt ttgtatattc agtttaaaaa gctggaacta tacttccttt atattcatct
     3721 tgtataaatt ttttaacttc tttactattc atagcctctg ataaagcctt aatcttatca
     3781 ctatctttat tattttctct acaagctatt atatttacat atggagaatc acttgattct
     3841 attactattg catccttagt aggatttaag ttagctgtta aagcataatt agaatttatt
     3901 actgctccgt caacatcttt taatactgtt ggtaattgct ctgcattcat ttcttttatt
     3961 actatatttt taggattttt agttatatct tttttagtta taagctctcc atcttttact
     4021 tctatcaatt tattttttgc taataattta agtgctctag ctccattagt tgcatcattt
     4081 ggcacagcta taacagctcc atcttttaat tcatctaatg acttaacttt ttctgaatag
     4141 aatcccattg gctctatatg aactttagat gtataagtaa gtttatatcc tttctccttc
     4201 acagtttcct ctaaaaatgg aatatgttga aagaagttag catccaaaga cccttcatct
     4261 aaagctgtat ttggaagtac ataatcatca aatattttta cttctaaatc atatcctttt
     4321 tcttttaaca aaggttttgc aacttccaat atctttgcat gtggatttga tgaagctcct
     4381 actagtattt ttttatcctc tttgtttgaa caacctactg ctgatattgc tattgctgac
     4441 accaatgcta ctgataataa tttctttaat ttcattttta ctccccctct ttaaaatgtt
     4501 tataattaat ttattttagt ttcttataag ccagatttcc tactccctgg attatctgaa
     4561 ctaatattat aagtgctatt acagtatata ccattactgc tgtatcaaat ctttgatatc
     4621 cataaataag tgctatatta cctaatcctc cagctcctac tgcacctgcc atagctgtat
     4681 aaccaagtat agatattatt gataatgtaa ttccagatac tattgaaggc atagcttcct
     4741 ttatcataac tttaaatact atttgtcttt ttgtagctcc aaaagatttt gctgcttcta
     4801 tcaatccttt atcaacttca tttaatgagc tttctataat tctagcgata aacggtgctg
     4861 ccccaatagt tattggcact attgcagcag tttcccctat acttgttcca acgattaatc
     4921 tagttattgg aatcattgca actataagta tcataaatgg gaaacttcta aatatattta
     4981 ctataaatcc taatgcacta tttattgtgc tatttggttt taatccatct ggttttgtaa
     5041 ctactaatat gattgctaat ataaatccta atattgttgc cactatagtt ggtactataa
     5101 ccatatacaa agtttgtaac aatgcatttg gaaatagtgt tgttaaaaag tcaattaaac
     5161 tattcattta tcatttcctc ccatcttatg cccttactag ttagatattg ttttacttgc
     5221 tctccacttt tatctgaaat gtttataata agtgaaccta aaatatcatc tttaaattgt
     5281 tctaatttcc caaatattat agacacatct atatttagtt ctcttgccat agtcgtaata
     5341 atagcttcat tagaaatatc tttagggaat agtatcttta tatttgttcc ttttggcaat
     5401 attatacttt cttcacctat taattttcta agtcctttag tatttcttaa gaatatttct
     5461 tctgtatctc ctacctctaa tacttctcca ttttccatta ttgctactct tccacaaatc
     5521 tgctttataa cttccatttg atgagttaca actattattg ttattcccaa ttttttattt
     5581 atatcttcaa gcaatgaaag aattgacttt gtagtatttg ggtctaatgc tgaagtcgct
     5641 tcatcacaaa gaagtacttg tggatttagt gctaaagctc tagcaattgc aaccctttgt
     5701 ttttgtccgc cacttagatt tctgggttta tcatttttct tttcagatat tccaactact
     5761 tctaataact ctaaaactct ttttttaatt tctgcctttg agtatccaaa acattctaat
     5821 ggcaatgcta cattatcaaa tacagttttt ctttcaagca atgaaaagtg ttgaaaaatc
     5881 attcctaact cttttcttaa atctctcatt tgcttttcat tcaatgactt tacttcttta
     5941 tcagaaacaa gtacactgcc ttcttggtat tcttctaatc cgtttataca tctcagtagt
     6001 gttgatttcc ctgcaccact atgacctatt attccaaaaa tttctccaga ttctatttca
     6061 atacttacat ctttaagcac ttgaatcttt ccataatact tattaacatt ttttatgcta
     6121 atcataaaat ttcctcccat atattctgct cagtttttat gtttatcctc tcttatgtat
     6181 tacaacaaaa taaaagcccg agtataaact caggcttaga aagctattta tactcatcta
     6241 tcaactatat tagttgcagg atttagcacc aatgtatata aaatatactg gttgccgggt
     6301 ttcaaagggc cagtccctcc accactcttg ataagacgtt atttaattta attctattat
     6361 catttgttgc tatgttatat atgatatatt cattaatagt atttgtcaat aaatttattt
     6421 aaatttttta ttttttatta tcgttaatta actattttta attagttttc tagctcctaa
     6481 cactttatat tttaatgtct atataactat agaacatcat tataagaaat aaattaaata
     6541 acatcaatct atctaaatca tctgtaaagt aaattaagaa aattaacatt ttatccaaac
     6601 tctatcctac tattaaataa aataatttaa atacaatgat gattatatag ctctagtact
     6661 ttagacttta tcaaatgttt aagttctata ggttctatta ttgtagcatt tttcccaaaa
     6721 gttaaaaaat attcagccac ccagttaagt gtagattttg gtatatacat atctatgtat
     6781 ccacctttag acaagatttt caaccctctt gccaacaaaa attctgtttc acaacgtttt
     6841 actccctcat ctgtcaaatt aattttaata tgataatctg tacctacttc catattctta
     6901 agataatcat gtatagaaga taaaacctta tatttcttac ttgataagtt ttctatactc
     6961 aaaatcttca caattctgtc tacacgaaat tccttaatag attctgattt tatacagtaa
     7021 gctggacaat accaaagtcc attcatggca tacaaaccaa taggaacaat ggtacgtaca
     7081 ctattttttt gctttgatga atattcaatt ttaattgtaa attcattcat tactatatta
     7141 aacaattctt tcaataatgg tgttgaacag tgcctatctg gtgtccaaaa aacaaattta
     7201 cgccttatat tctcaatatt atattgaata tcatttggta tacaatttaa aaattttttt
     7261 aaaacagaaa tagtttcttg ctcaaatggc aaatcattat aatattctag tgactgatat
     7321 gcaaagaata tagattttac ctcactttct gaaaatgcaa tcggtggaag tatacgctct
     7381 ttaagtacat gatatccacc agccgctcca acttttgaat ataatggaaa tccaatactc
     7441 tccagcacct gtaaatctct tagtatagta cgttttgata cagaaaattc ttctgctaat
     7501 tctcctgctg taaaacttct ttttgcattt attgttatca tcagttcaat taaacgctca
     7561 gctcttgaca tatttatact cctaatttaa atatagtgac aataattgtc actattatat
     7621 gataagatat tcttgcatct aaagcaataa taatagtaaa gaaagaaggg attgatactt
     7681 tatggaaaat gatactatta aggctgatga tattctcaat tattgtctat caaacttaga
     7741 tgatgttgta ctaatggata gttgggggga acgagcaatt tactacaatc ctaatggtgt
     7801 tttaaagcga ggggtatatg ttcttaccat taaggaaaaa gacagtaata atgataaagg
     7861 ttcgttagtt agtcgtccaa atgtataccg tgtgaatata ggattaaaaa aagaaacttt
     7921 tattgaaatg tttggatata ttccaaagcg tccaggtgta ggtcaaatag ttgatatgga
     7981 ttttgatttt acaaaattgg acacaatcat gccacatcct atctactcat ggatgggatg
     8041 gatatgtgtc ctaagcccta ctgaaaagac atttgagaac tttaaaactt taataggaga
     8101 atcttacaat tttgcaaaac aaaaatttaa aaagagaaaa aacaagtaaa aacgtgtgaa
     8161 aataacctct aaataaatta taataaaaat attaaggtta caagataaaa attaatatct
     8221 taataacatg caaaaaagcg aagccaaaaa atgtattatt tataaggctt cgctatatct
     8281 caaataattt atttcaaatt tcaaaactat ttattctatt atttcttatt atttcctgtt
     8341 attcctaatc tatcattcat atcttttatc atttttctaa aaccactacc tatatcattt
     8401 ccaacatctt cagttccatg aactaatttt ataaagtcat tttgaccttt tttcatatct
     8461 tcatcagata ccttatctaa tttttctatt ctcttatcta tatcttttac taatctttcc
     8521 ccttcagcga ttaggtcatc attcattttc tttaactctg tatcttctgt tttaccatct
     8581 tttttaagag atgttacaaa tgattgtatt ttatctctac tatctttata tgcagccttt
     8641 acatcactta gatatttttc atttcctgga tattctttat ctttaaactg attatttata
     8701 ctttctggag tatcataaat agaatatcta tttagacctg ctatataatc attatagctt
     8761 gttgaataat aattcatata tccttcatta ttatttacag attcattagg attttttcct
     8821 gtattttcac ttggtttttc attattttta gtacatgcag ttatacctat agctaatact
     8881 agtgctaatc ctacaaataa agttcttttt aatttcattt ttattaccct cctagatgtt
     8941 ttatactata aaaaatttta ataattttct ttcttaattt agtatttcta ta
//
LOCUS       DAMKNB010000114         8887 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.120, whole genome shotgun sequence.
ACCESSION   DAMKNB010000114 DAMKNB010000000
VERSION     DAMKNB010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8887)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8887)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8887
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.120"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            85..816
                     /locus_tag="PC494_003271"
     CDS             85..816
                     /locus_tag="PC494_003271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3913742.1"
                     /translation="MLSKKNVSLIILVIILSLLTAIFIFNNKNTNNKLKEVTKNNEEI
                     VPKNLEGLSIEQLIEIRDKAIDKNLEGLREFGEDSVKKRKDSILNFEFGLVAFVNKNY
                     SNLTEKEKLIRQINIVNYENSINDIMDPSGSFFELANQNYQVNEFLLKNGKDYKEWSY
                     EGLDFLIDHLEELCKFVDFDVKDVIDIIDPTIKTDLSEEQKKSLNDKLKKISSSDTLS
                     EEVKKEIKNWENNLNNLNMNKNNSN"
     gene            complement(973..1179)
                     /locus_tag="PC494_003272"
     CDS             complement(973..1179)
                     /locus_tag="PC494_003272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3913743.1"
                     /translation="MSKYSSLWEYVKKNNSQSFKLTFEEIKDIAGIEIDHSFLKYKKE
                     LNEYGYQVGKISLKEKTVIFDKIG"
     gene            complement(1582..1977)
                     /locus_tag="PC494_003273"
     CDS             complement(1582..1977)
                     /locus_tag="PC494_003273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine 5'-phosphate oxidase family
                     protein"
                     /protein_id="HDF3913744.1"
                     /translation="MKALEFLNKARVYYLATVDENNQAHVRPLGFVMEYNGKLTFCTS
                     NQKDMFKQLIFNPKVELCCIDQNLNTLRILGEAVFVTSKETQAKALEIMPSLGQMYSV
                     GDGKFEIFSIDKAKVSCCSMSGKKIDVEL"
     gene            2118..2510
                     /locus_tag="PC494_003274"
     CDS             2118..2510
                     /locus_tag="PC494_003274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF3913745.1"
                     /translation="MSINTEKNITKNVEELTCPIRYALDIVGGKWKLPIICMLAVENP
                     IRYSSIKRKLDGITNTMLAQSLKDLESTGIVHRKQYNEIPPKVEYTLTSKGKSIVPIL
                     QQFANWGATNMQEKNTCGLSCKECRKIK"
     gene            complement(2610..3026)
                     /locus_tag="PC494_003275"
     CDS             complement(2610..3026)
                     /locus_tag="PC494_003275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3788 domain-containing protein"
                     /protein_id="HDF3913746.1"
                     /translation="MNWQDAFFQDTKPKFEQINEFINNPLWDKLNKTLVSTYNVEPKL
                     EYSKCSMQRGWNVKYKKRGKSLCTLYPQEGYFKALVIVSESNRVEVDLFINTCCDYIK
                     KIYNEVNFFNGSKWLMIQVDSLLVLNDMLELIKFRA"
     gene            complement(3041..3952)
                     /locus_tag="PC494_003276"
     CDS             complement(3041..3952)
                     /locus_tag="PC494_003276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HDF3913747.1"
                     /translation="MHAWESIQITLDLIEANLSEEISINELANKANLSPFYYQRLFKR
                     LVNKTVMEYIKLRRLARASEYLAEHKNRILDVALNFGFASHETFTRSFKKAYGLTPEK
                     YRANPVKLNHFIKPELILNYAMVDEGVPLIADDIVIEVNRKTLSNPRTFVGIEIEVPI
                     CQLVGGETTGIAIVEELWMKLGSQRHNIPNQIPGGNEFAALYMGNAKEGNCMYMAGVE
                     VESGTSVEGYSTFELPAKEYLVCGFEAENFNELVNSAVFKADKFMERWMKKHNLTTTD
                     FAIEMYYPTTPEAAYLEHWIVPVPIEQ"
     gene            complement(4134..5156)
                     /gene="splB"
                     /locus_tag="PC494_003277"
     CDS             complement(4134..5156)
                     /gene="splB"
                     /locus_tag="PC494_003277"
                     /EC_number="4.1.99.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore photoproduct lyase"
                     /protein_id="HDF3913748.1"
                     /translation="MFNPKRIIFEKGTLDTDVGKKIYNKFRDNKDVEIINISSNRIKE
                     HIPGENLYEQYRSGKQTMVVGIRKSLKFQTCKPSANYQLPLVSGCMGRCEYCYLNTQL
                     GDKPFIRVFVNVDEILEQTKKYIEDRKPQVTIFEGAATSDPVPVEPYTNSLKKTIEFF
                     GREEKGRFRFVTKYSDVDSLLDAEHNNHTEIRFSINTPRIINEHEHYTASANKRIESA
                     VKLARAGYQIGFIIAPVFLYEGWKEEYKNLIISIKEALPKDFDKKIIFEVISHRYTTK
                     AKNRILEIYPDTLLPMENEDRKFKYGQFGYGKYVYDKEQLDDMKEFFLKEINGVFKNS
                     LIKYII"
     gene            complement(5383..6513)
                     /locus_tag="PC494_003278"
     CDS             complement(5383..6513)
                     /locus_tag="PC494_003278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HDF3913749.1"
                     /translation="MNFNYNLPVNILFGRGRINDVGKEVSKYGKKVLIVTGKNSTKKT
                     GLLDKTIDLLKDSKIEYEVFDRVEQNPLITTIYSGVEIIKSTGCDCVLGLGGGSIMDA
                     AKSIAFSYKNPGDLNDYIFGIRQGEEALPIILVPTTSGTGSEGNCFAVLTNSETKDKK
                     SIKKNSMYAKASIIDPELMVTMPKHIIASVGFDALAHNMEAYLSNGRNPLADVQAIYG
                     IELISENLIKVYNDVNDLEAWEKITLASTIGGMTIGTAGTALPHGMEHPVSGLRDVMH
                     GKGLAALTPTIIESSWDSDIERFGNISKVLGGTCAEDCSDAIRNFLKKIDLDIKLSDL
                     GIEKSDIDWLTDNCMKISVANIKRHPKYFNKEQIKEMYHKSL"
     gene            complement(6901..8838)
                     /gene="htpG"
                     /locus_tag="PC494_003279"
     CDS             complement(6901..8838)
                     /gene="htpG"
                     /locus_tag="PC494_003279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone HtpG"
                     /protein_id="HDF3913750.1"
                     /translation="MEFEKGSISIHTENIFPIIKKWLYSDKDIFIRELISNGCDAVSK
                     HKRLVSLGEISENKSSDYKITVSVNKGEGTLKFIDNGIGMTEEEIKKYINQVAFSGAE
                     DFFNKYKDKMEESNDIIGHFGLGFYSAFMVSKKVQIDTLSYTEGATPVRWISEGGTEY
                     EISESDARNDRGTTITLFIDDDSKEFLDEFTVRGIINKYCSFLPVEIYLEDVERLERE
                     AKEAEEKAKKQKEDGKEEIVDAKVIEPLNDTNPLWLKSPKDCTDEEYKEFYRKVFNVF
                     DEPLFWIHLNVDYPFNLKGILYFPKLKNEFELTEGKVKLYNNQVFVADNIKEVIPEFL
                     LLLKGVIDCPDLPLNVSRSFLQNDRDVSKISKHIIKKVADKLKSLCKNEREEYNKFWD
                     DIQIFIKYGCLKDESFYEKVKECILFKTIDDEYITLQDYLEKCKDKHENKVFYVSDKE
                     QQSQYIKLFKEYDLSAVVLNSSIDTHFISFMEYKENGVKFNRIDADLSDVLKDKNENK
                     DSEENKEEIAKIEGLFKEAVGERVKNYSVEGLKNEDTPAMVLVSEQSIRMAEMQSRFA
                     GMDLGMNFEEEKTLVINENSPIIKKLVSLKDDEEKKDKITLICNQIADLALLSNKELK
                     PDELDSFVQRSNKLMSLLIEL"
BASE COUNT         3020 a         1444 c          945 g         3478 t
ORIGIN      
        1 tagaacaaac agtagtaaat gttatcttca taaacaaatt tatttttcac aagtacaata
       61 cttatttaaa aaaggaggtt taatatgtta agtaaaaaaa atgtaagttt aattatttta
      121 gtaataattt taagtttatt aactgctata tttattttca ataataaaaa tactaacaat
      181 aaattgaaag aagttactaa gaataatgaa gaaatagtac ctaaaaactt agaaggttta
      241 agtatagaac aattaataga gattagagat aaagccattg ataaaaattt agaaggtctt
      301 agggaatttg gagaagattc agtaaaaaaa cgtaaagatt caattttaaa ctttgaattt
      361 ggattagtag cttttgttaa caagaattat agcaacttaa cagaaaaaga gaaattaata
      421 agacaaatta atattgttaa ctatgaaaac tctataaatg atataatgga tccttcaggt
      481 tcattctttg aattagcaaa tcagaattac caagtgaatg agtttctatt aaaaaacgga
      541 aaagattata aagaatggtc atatgaaggt ctagattttc taattgatca tctagaagaa
      601 ctgtgcaaat ttgttgattt tgatgtaaaa gatgtaatag atattattga tcctacaata
      661 aaaacagacc tttcagagga acaaaagaaa tctttgaatg ataaattaaa gaaaatatct
      721 tcaagtgata ctttaagtga agaagttaaa aaggagataa aaaactggga aaacaattta
      781 aataatttaa atatgaataa aaataattct aattaatttt ctcataagaa aaatgcttat
      841 atcgtgataa tgtgaaatgt acataattat aaacaaaaaa ggggctgtga cactaaaaaa
      901 tagtgctacg ccctttttta tttgtaataa tcatcaatac aaattatttt attatatgta
      961 attatttatg tcttaaccaa ttttatcgaa aataacagtc ttctctttta aagagatttt
     1021 tcctacttga tatccatatt catttaattc ctttttatat ttcaaaaacg aatggtctat
     1081 ctctatccca gcaatatctt ttatttcttc aaaagttaat ttaaacgatt gactattgtt
     1141 tttcttaaca tattcccata aagaactata tttactcatc ttatatcact ccttttaaaa
     1201 tcatatctta tctattaatt tatattctat cattattaat gtataaagtc atgctactta
     1261 ttatttatat ataaaaatat ccaaataata agtagcaatt ttttatagtc ataatatttt
     1321 tttcagatta aataaaaatc aattatagtt aaaatatttt ttaaaagaaa tctatcccat
     1381 tataaagtaa attttaatta tcttatttct agtatgtaat tattcaaaat agtatatcat
     1441 tattgaaata cacatctaat aactaaaaat ttttacatat tcattattta aaaatctttt
     1501 tattgcattt aaattaaatc tatcaacatt tcagtaataa cgttttctta attttcacta
     1561 tggatgtcga ttcaattata attaaagctc tacatcaatc tttttaccac tcattgaaca
     1621 acaactaact tttgccttat caatagagaa tatttcaaac ttaccatctc ctacagagta
     1681 catctgacct aaacttggca ttatttcaag tgccttagct tgtgtttctt ttgatgtaac
     1741 aaatactgct tcacctaaaa tacgtagagt attaaggttt tggtctatac aacaaagttc
     1801 aacctttgga ttaaaaataa gttgcttaaa catatccttt tgattagatg tgcaaaatgt
     1861 aagtttacca ttgtattcca taacaaatcc taaaggacgc acatgtgctt gattgttctc
     1921 atcaactgtt gctaaataat aaactcgtgc cttgttcaaa aattctaatg ctttcataat
     1981 tcttacaccc cttttaaata cttgtattaa ggattatcct ttgatataat tttaatataa
     2041 aatacagaaa aaacaagtat gcagtttttt ctgataaagt ataaaaaaga tactactata
     2101 actaaggagt aattaaaatg agtataaata ctgaaaaaaa tataactaaa aacgttgaag
     2161 aattaacctg tccaatccgt tatgcattag acattgtcgg tggtaagtgg aaattaccta
     2221 ttatatgtat gttagcagtt gaaaatccaa ttagatatag tagcataaaa agaaaattgg
     2281 atggcattac aaatactatg ctagctcaat cattaaaaga tttagagtct actggtattg
     2341 ttcatcgtaa acaatataat gaaattcctc caaaagttga atatacatta acaagtaaag
     2401 gtaaaagtat tgtgcctatt ttacaacaat ttgctaattg gggtgctact aatatgcaag
     2461 aaaaaaacac atgtggactt agttgcaaag aatgtagaaa gataaagtaa atttaaattt
     2521 actaaattat tcatattata gactatatat taatttatct gattgaatat aaaaacagga
     2581 tgacttatat attcatcctg ttctatatgt taagctctaa atttaattag ttcaagcata
     2641 tcgtttaata ccaataaact atctacttga atcattagcc atttacttcc attaaaaaag
     2701 tttacctcat tatatatttt tttgatataa tcacaacaag tattaataaa taaatcaacc
     2761 tctactctat tgctttcact tacaataacc aaagctttaa aataaccttc ttgtggatat
     2821 aaagtacata gtgatttacc tcttttttta tattttacat tccaacctct ttgcattgaa
     2881 catttactgt attcaagctt aggttctaca ttataagtag aaaccaaagt tttatttaac
     2941 ttgtcccata atggattatt aataaattca ttaatttgct caaatttagg tttagtatct
     3001 tgaaaaaacg catcttgcca attcatattc atcatccttt ctattgttca ataggaaccg
     3061 gaacaatcca atgttccaga tatgctgctt caggtgtagt ggggtaatac atctcaattg
     3121 caaaatcagt agttgttaaa ttatgtttct tcatccatct ttccataaat ttatctgctt
     3181 taaaaacagc tgaattaact aactcattaa agttttctgc ctcaaatcca catactaaat
     3241 attctttagc tggcaactca aaagtactat atccttctac tgatgtacct gactctacct
     3301 ctacacctgc catatacata caatttcctt cttttgcatt tcccatataa agagcagcaa
     3361 attcatttcc acctggaatt tgatttggta tattatgtct ttgacttcca agtttcatcc
     3421 ataattcctc tactattgca attccagttg tttcaccgcc caccaactgg caaataggta
     3481 cttctatttc tattccaaca aatgtccttg gattactcaa tgtcttacga ttgacttcaa
     3541 tcactatatc atctgcaatc agtggaacac cttcatcaac catagcataa tttaaaatta
     3601 attctggctt aataaagtga ttgagtttta ctggatttgc tctatatttt tctggagtta
     3661 atccatatgc ttttttaaag gaacgtgtaa atgtctcatg actagcaaat ccaaaattta
     3721 aagctacatc aagtatacga ttcttatgtt ctgctaagta ttcagaagct cttgcaagac
     3781 gacgaagctt tatatactcc attacagtct tatttaccaa tcttttaaat agtctttgat
     3841 agtaaaatgg tgataaattt gctttatttg ctaattcatt aattgatatt tcttctgata
     3901 aatttgcttc tattaaatcc aatgtaattt gaatagactc ccatgcatgc atactataac
     3961 tcctcctgat atttttgtta ctcttatcct ttatagtatc aaaactagaa aaaatgttct
     4021 tgatagatag tgcccttttt aattttctta tatgatagtg ctaaatctca ttgctttatt
     4081 ataaacataa aatgtataaa aataaaatat agcaaatctt taggtaagat ttgctatatt
     4141 atatatttta ttaaactatt tttaaatact ccatttattt ccttaagaaa gaactctttc
     4201 atatcatcta attgttcttt atcatacacg tacttaccat atccaaattg accgtattta
     4261 aactttctat cctcattttc cattggcaat agtgtatctg gataaatctc tagtattcta
     4321 ttttttgctt tagttgtata tctatgagat ataacttcaa atataatttt tttatcaaaa
     4381 tcctttggta aagcttcttt tatacttata atcagatttt tatactcttc tttccaacct
     4441 tcatataaaa acacaggtgc tattatgaaa ccaatctgat aaccagccct agcaagtttt
     4501 acagctgact ctattctttt atttgcagag gctgtataat gctcatgttc atttataatt
     4561 ctaggagtat tgatactaaa tcgtatttct gtatgattat tatgttcagc atccaataag
     4621 ctatccacat cactgtattt agtaacaaat ctaaatcttc ctttttcctc tcttccaaaa
     4681 aactctattg ttttctttaa agaattagta tatggctcta ctggaactgg gtctgatgta
     4741 gctgcccctt caaatatggt tacctgtggc tttctatctt caatatattt ttttgtctgt
     4801 tcaagtattt catctacatt tacaaacacc cttataaatg gtttatcacc taattgtgtg
     4861 ttcaaataac aatactcaca tcttcccata catccactga caagtggtag ttgataatta
     4921 gcagaaggtt tacatgtttg aaacttcaga ctttttctaa tcccaactac catagtctgc
     4981 ttcccacttc tatattgttc atatagattt tcacctggaa tatgttcttt aatcctattt
     5041 gatgatatat taattatctc tacatcttta ttatctctaa atttattgta tattttttta
     5101 cccacatcag tgtctaaagt tcctttttcg aatattattc ttttgggatt aaacatttat
     5161 ttcacctcta cttaaagttt ttaaatcgaa gaattttata aaatattact taattaatct
     5221 tccctttttt aaactccttt atttattaga aagtaaaata aaagcttaag acaaatttat
     5281 tatatatata acttctatac acaatttttt tactattaat tacttataat tttttattat
     5341 taatttataa tttttatata aaactaaata tgtaaagtca aattataaag acttatggta
     5401 catttccttt atttgttcct tattaaaata ctttggatgt ctcttaatat ttgcaactga
     5461 tattttcata caattatcag ttaaccaatc tatatctgat ttttcaatac ctaaatcact
     5521 tagttttata tctaaatcta tttttttaag gaaatttcta attgcatctg aacaatcttc
     5581 tgcacaagtt cctcctaata cctttgaaat attaccaaat ctttcaatat cactatccca
     5641 tgaactttct ataatagtag gagtcaaagc tgcaagtcct tttccatgca ttacatctct
     5701 aagaccactt acaggatgct ccattccatg tggcaaggct gtacccgctg taccaatcgt
     5761 cattcctcca atagtacttg caagtgttat tttttcccat gcttctaaat cattaacatc
     5821 attatatacc tttattaggt tttctgatat aagttcaatc ccataaatag cttgtacatc
     5881 tgcaagaggg tttcttccat tagaaagata tgcttccata ttatgggcaa gtgcatcaaa
     5941 tccaactgat gcaattatat gttttggcat tgtaaccata agttctgggt caattattga
     6001 tgcttttgca tacatactat tcttctttat agatttttta tctttagttt ctgaatttgt
     6061 aagtactgca aaacaatttc cttcactacc tgtacctgat gttgttggaa ctaagattat
     6121 aggtaaagct tcttcacctt gtctaattcc aaatatataa tcatttaaat ctcctgggtt
     6181 tttataagaa aaagctatac tcttggcagc atccataatg cttccaccac caagacctaa
     6241 aacacaatca catccagttg attttataat ttctactcct gaatatatag tagttataag
     6301 aggattttgt tctactctat caaaaacttc atattctatt ttagagtctt ttagtaaatc
     6361 tattgtttta tcaagtaatc cagttttctt tgtactattt ttacctgtta ctatcaatac
     6421 ttttttgcca tatttagata cttcttttcc cacatcatta attctgcctc tcccaaataa
     6481 gatatttact ggcaaattat aattaaaatt catgctaaaa cctcctattt ctactttagt
     6541 aataatttta tgtttttaac aaagtgtaat tatgtattta aacataaact aaaaaacaat
     6601 cttttactta attatatgta ttatcttatt atatatcaag ttaactatat ttaactaaat
     6661 agagtttttt attagaacct acttaaatat ttaaaaatta accaaagata aaaaaataaa
     6721 gaacggtctg tctcaaaata gagataaata tatttttcat tgttgaaatg attaaaataa
     6781 atttaatttc acataaaaaa agcgcctcat gaactgaaaa gttcattttg agacacttct
     6841 ttctcatcac tgatattgaa tactttttat aaatttgctt caatgtattc aaattcaatc
     6901 ttacaattct atcaaaagac tcataagctt attacttctt tgtacaaatg aatctaactc
     6961 atctggcttt aattctttat tagaaagtaa agctaaatct gctatctggt tacaaataag
     7021 cgtaatctta tctttctttt cctcatcatc tttaagagaa accaattttt tgattattgg
     7081 actgttctca tttattacaa gagttttttc ttcctcaaaa ttcattccta aatccattcc
     7141 agcaaatctt gactgcattt ctgccattct aatagattgt tctgatacta ataccatagc
     7201 tggagtgtct tcatttttca atccttctac agaataattc ttcactcttt ctccgacagc
     7261 ttctttaaac aaaccttcta tcttagctat ctcttctttg ttttcttcac tatctttatt
     7321 ttcattttta tcttttaata catcagaaag gtctgcatct attctattaa acttaactcc
     7381 attctcttta tattccataa atgaaataaa atgagtatct attgatgagt ttaaaacaac
     7441 agcacttaag tcgtattctt taaatagttt aatgtattga gattgctgtt ccttatcact
     7501 tacataaaat accttatttt catgtttgtc cttacatttt tctaaataat cttgtaatgt
     7561 tatatactca tcatcaatag ttttgaataa tatacattct tttaccttct catagaaact
     7621 ttcatctttt aagcaaccat atttaataaa tatttgtata tcatcccaaa acttattgta
     7681 ttcttctctt tcatttttac aaagagattt caacttatca gctacttttt taattatatg
     7741 tttagaaatt ttgcttacat ccctgtcatt ttgtaagaaa cttcttgata catttaatgg
     7801 taagtctggg cagtctataa ctccttttaa taaaagtaaa aattctggta taacttcttt
     7861 tatattgtca gccacaaaca cttgattgtt gtataatttt acttttcctt cagtcagttc
     7921 aaactcattt tttaatttag ggaagtaaag tatacccttt aaattgaaag gataatctac
     7981 atttaaatgt atccaaaata aaggttcatc aaatacattg aatacctttc tataaaactc
     8041 tttatactcc tcatcagtac agtcttttgg agattttaac catagaggat tagtgtcgtt
     8101 taaaggctca attacttttg catctacaat ctcttctttt ccatcttcct tttgtttttt
     8161 agctttttct tctgcttctt tagcttctct ttctaatctt tcaacatctt ctaaatatat
     8221 ttctactggt aagaaagaac agtatttatt tattattcct cttacagtaa attcatctaa
     8281 aaattcttta ctatcatcat caataaatag tgttatagta gttcctctat catttctagc
     8341 atctgattca gatatttcgt attctgtacc accttcagat atccatctta caggagtcgc
     8401 tccttctgta tatgaaagtg tatctatttg taccttttta gacaccataa atgcagaata
     8461 aaatcctagt ccaaaatgac ctattatatc atttgactct tccattttat ccttatattt
     8521 attaaagaaa tcttcagcac ctgaaaaagc aacttgattt atgtattttt ttatctcttc
     8581 ttcagtcata ccaattccat tgtcaataaa tttaagtgta ccttctcctt tatttacaga
     8641 tactgtaatt ttataatctg atgacttatt ttctgatatt tctcctagtg atacaagtct
     8701 tttatgttta cttactgcat cacatccatt acttataagc tctcttataa atatgtcttt
     8761 gtcagagtat aaccattttt taattatagg aaaaatattt tctgtatgaa ttgaaatact
     8821 ccctttttca aattccattt tttatccctc ctcattttat aattaatatt ttaaattttt
     8881 taaaatg
//
LOCUS       DAMKNB010000115         8876 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.121, whole genome shotgun sequence.
ACCESSION   DAMKNB010000115 DAMKNB010000000
VERSION     DAMKNB010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8876)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8876)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8876
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.121"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            complement(331..1227)
                     /locus_tag="PC494_003280"
     CDS             complement(331..1227)
                     /locus_tag="PC494_003280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HDF3913751.1"
                     /translation="MKDKNTYFNRKGQENFIDIFLKDDIKKGANFKRHWHEHLQIYYF
                     IDGIAYLECGLDNFKVVPGNIVIANSNELHYLESLSDNLKFYSIRIEPTFLFSNQVDL
                     LQTKYLAPLALNHIVFNNLIQNDSLILKCITTILDEYHNKEVGYELSIKANIYQLIVL
                     LLRSHIDKIYSEDEFIKRKYSLEKFECIFDLIEEKYMDKITLKELASRVNLSAHHFCR
                     TFKQITGKTTIDFINGIRIDKAIYYLKETDLNMTEIAMRCGFDSINYFSRLFKRNYNI
                     SPTKYRNEHREVSNVILKEDMK"
     gene            1368..2795
                     /locus_tag="PC494_003281"
     CDS             1368..2795
                     /locus_tag="PC494_003281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDF3913752.1"
                     /translation="MTNSFKKDDNRKKITVLFVVIAMTFMATLDSSIINVALPVLASK
                     LNVSLASIEWVIASYSIIICSTLLFFGRLGDIIGKSRVFQVGTILFTSASLLCGLSNS
                     LTLLIVCRFIQGIGASAYMANNHGIITELFPKESRGKALGILVTAVAIGNMVGPSVGG
                     FILSIFDWNVIFFINIPIGLIVIFLNTKFLPNSKKSSENMDKTGAILQFLGTTLFFSA
                     LISAQQTGLLNPYILIALLLSIIFIILFLILEKKHPQPLLDLEIFRNFKFSLNLICAL
                     TSFICIASSSILIPFYLQSTMKLPPIQAGLFMILSPLILAIFSPIFGNISDKIKSEKI
                     ILIGLLVMSFGFFLMSRLKESSALILFVIYISIISIGQAIFQPANNALIMSSCSRSKL
                     GVVGSINSLVRNLGQVIGITISTTLLYNFMSIKAGYRVNDYVINNDKIFVFGMRNVYI
                     IVTLVCLIGAILIGFYLFKYNKNEQ"
     gene            complement(2991..5585)
                     /gene="clpB"
                     /locus_tag="PC494_003282"
     CDS             complement(2991..5585)
                     /gene="clpB"
                     /locus_tag="PC494_003282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent chaperone ClpB"
                     /protein_id="HDF3913753.1"
                     /translation="MDVEKMTLRVQKSLNEAYNEAVKNHNQQVDVIHLFSALINQEDG
                     LIPNIIEKMNISIDSLRNTVNFEIDKLPKVYGEGADSQGVSATRKINEVLIKAESISK
                     EFKDSYISVEHVMLAMMETESKSAVGKILKQYNINKNDFLNILSQVRGSQRVETQDPE
                     GTYDALARYGTNLVDLAKKNKLDPVIGRDEEIRRIIRILSRRTKNNPVLIGEPGVGKT
                     AIVEGLAERIVRGDVPEGLKDKIVFSLDMGALIAGAKYRGEFEERLKAVLKEVQSSDG
                     KIILFIDEIHTIVGAGKTEGSMDAGNLIKPMLARGELNCIGATTFDEYRKYIEKDKAL
                     ERRFQPVIAEEPTVEDTISILRGLKERFEIHHGVRIHDNAIVAAAKLSHRYIQDRFLP
                     DKAIDLIDEAGAMIRSEIDSLPTELDVVRRKLFTLETEREALLKENDDKSKSRLDDIQ
                     KEIAELKSKNDEMTAKYEKEKSQILDIKNLKAQLDEAKGKAEKYEREYDFNKAAEVKY
                     GEIPKLEEQIKQYEENMNDGSENSLLKEEVTEEEISSIVSKWTGIPVTKLVEGEREKL
                     LKLEDELHKRVIGQDEAVTAVSNAVIRARAGLKDERKPIGSFIFLGPTGVGKTELAKT
                     LARNLFDSEDNIIRIDMSEYMEKHAVSRLVGPPPGYVGYEEGGQLTEAVRRAPYSVIL
                     FDEIEKAHEDVFNMFLQILDDGRLTDNKGKTVDFKNTLIIMTSNIGSNYLLEAGGNIT
                     ETTNNLVMNEMKHRFKPEFLNRVDDIIMFKPLDQENIKKIIDIFMKDLKNRLKEKDIT
                     IEVTNSAKDVMVREGYDPVYGARPLKRYIGNTLETIIAKKLIAGDVYNGCTIVIDGKD
                     ENIEVLVK"
     gene            complement(5622..6218)
                     /locus_tag="PC494_003283"
     CDS             complement(5622..6218)
                     /locus_tag="PC494_003283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3913754.1"
                     /translation="MSLKLDRNVLQWFDYVFENEKTSLRHYNFNCTLKEISSTSLNKV
                     AFILEKNNSKYWKLYFEIPAEVTLKLKQNIHPLFREYIYEQISLYNNNQIYNFVNSNI
                     LKVFNNIAIYQYNILENLYTIDFKKSFIDKCQYLLIGEKRLIDEDLYLIAKSKEVFDF
                     FNSDGTFNLTLSFDIQKNENLLDSLLELRKSIIINERI"
     gene            complement(6235..6639)
                     /locus_tag="PC494_003284"
     CDS             complement(6235..6639)
                     /locus_tag="PC494_003284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication/maintenance protein RepL"
                     /protein_id="HDF3913755.1"
                     /translation="MDKTLKKDLNQEYTESKSLVMNKSKYMNVCFKNYIKVVEGMYTK
                     RDLIPLKLINSMDKNNKIRKTLYELSCEFEYPKTSLSSLFTELKKMDFLQRVKNGEYM
                     INPHIAYKGSRADKESLLAEYNQIKRPNKVSK"
     gene            7006..7380
                     /locus_tag="PC494_003285"
     CDS             7006..7380
                     /locus_tag="PC494_003285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDF3913756.1"
                     /translation="MNIVISNSSGKPIYEQITTQIKSMIISGELPEGSALPSMRLLAK
                     ELRISVITTKRAYSDLERDGFIETVTGKGSFVSSKNMDFVKEEQFRLIEEYLQKAVDT
                     AKSSDITYDELKDILFLLYKGE"
     gene            7377..8240
                     /locus_tag="PC494_003286"
     CDS             7377..8240
                     /locus_tag="PC494_003286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF3913757.1"
                     /translation="MISMDAITIKNLNKTYKDFSLQDISFSVPKGSVMGFVGENGAGK
                     TTTLKAILNLISYDSGNIEIFGLDSKKNEKEIKEQIGVVFEGSNFHENLNTDHVSKIM
                     SKIYKNWNDTLFKDYLKKLRVPDNKLIKEFSKGNKMKLSIAVALSHKPKLLILDEATS
                     SLDPIVREEILDIFLDFIQDEEHSIILSSHITSDLDKIADYITFIHKGKIVFSENKDE
                     LIDTMGVLKCKPSDFDNLSREDYSYYRKSQFGYEVLLKDKHRFISRHPNCIVDNTSIE
                     EIMLFYVRGDK"
     gene            8240..>8876
                     /locus_tag="PC494_003287"
     CDS             8240..>8876
                     /locus_tag="PC494_003287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 transporter permease"
                     /protein_id="HDF3913758.1"
                     /translation="MKGLILKDLLNLKGNIKFILLFIIMFGFMSSLGDGNVNNFIGVI
                     IVLCTTMIVSTFSYDDLNKWDSYVLTMPINRNDIVLSKYLTMLIFSFIGVLVSLIVSV
                     TIGYFKNTLILNETLLINALILSISVCFGSLILPLIYKFGTERARLLMILCFLVPTLA
                     LLVFKSILENISSPISIEIILNTLVYSLPFVAILLFVISYFISSKIYSKKEV"
BASE COUNT         2967 a         1312 c         1025 g         3572 t
ORIGIN      
        1 tttaaatttt ctataaaaat catactattt tagctgttta cttgcttatt taatagtttt
       61 atttctttga ttaaatatct ttcagaatct aagccagatg tctcaaaaaa actgatttat
      121 aatataatca ttttttctgc tattcttatt tttccagttt tagtttcata ttaaaatata
      181 cttttcatag acactgcatt ctttcatact cattttcaca tttaactata caagtagtct
      241 tactcattta tgtactatac tttattaata tttattaaga aaaactcaaa gatttaaaaa
      301 tatatatttt ctataaagta tatttatgga ttatttcata tcttctttta aaataacatt
      361 actaacttct ctatgttcat ttctatactt agttggagat atattataat tccttttaaa
      421 taagcgacta aaataattta tgctatcaaa gccacatctc atagcaattt ctgtcatatt
      481 taaatctgtt tcctttaaat aatatatagc tttatcaatc ctgattccat ttataaaatc
      541 gattgtagtc ttacctgtta tttgcttaaa tgttctacaa aagtgatgtg cactcaagtt
      601 cacacgacta gcaagttctt ttaatgtaat tttatccata tatttttctt ctatcaaatc
      661 aaagatacat tcaaattttt ctaaagaata ctttcttttt ataaattcat cttcagaata
      721 tattttatca atatgacttc ttaataagag tactattaat tgatagatat tagcttttat
      781 agataactca tatccaactt ctttattgtg atattcatca agtatagttg taatacattt
      841 taaaatcaga gaatcatttt gaattaaatt attaaataca atatgattta aagccaatgg
      901 tgctaagtac ttggtttgta acaaatcaac ttgattacta aaaaggaatg tgggttcaat
      961 acgaatacta tagaatttta aattatctga taagctttct aaataatgta attcattact
     1021 gtttgctatt acaatatttc caggcactac cttaaaatta tccaatccac attcaagata
     1081 tgctatacca tcaataaaat aatatatttg tagatgctca tgccaatgtc ttttaaagtt
     1141 tgctcctttt ttaatgtcat cctttaaaaa tatatctata aagttttctt gacctttcct
     1201 gttaaaatat gtatttttat ccttcattat tcccccctca gcaaaatagt gctaattata
     1261 agcaatatag ttattgtatt cattatttca tatcgctatt atataaaatg taactatcat
     1321 tgtaaacatt aacataatgc agtcattata ataaggaggt aataaaaatg acaaactctt
     1381 ttaaaaaaga tgataataga aaaaaaatca cagttttatt tgtagtcatt gccatgactt
     1441 ttatggcaac attagattct agtattataa atgttgctct cccagttctt gcaagcaaac
     1501 taaatgtatc tctagcatct attgaatggg taatagcaag ttactcaatt attatttgtt
     1561 caacactatt attttttgga agacttggag atattattgg taaatcaaga gtatttcaag
     1621 taggtactat tctctttaca tcagcttcat tactatgtgg attaagtaat tctttaactt
     1681 tacttatagt ttgccgcttt attcaaggaa taggcgcttc tgcctacatg gcaaacaatc
     1741 atggaattat cacagaacta tttccaaaag aaagcagagg aaaagcccta gggattctag
     1801 ttactgcagt tgctattgga aatatggttg gaccatctgt gggaggattt attttgtcaa
     1861 tatttgattg gaatgttata ttttttataa atattccaat cggtcttatt gtaatctttt
     1921 taaatacaaa atttcttcct aatagtaaaa aatcttcaga aaatatggat aaaactggtg
     1981 ctatacttca atttttagga acaacattat tttttagtgc tctaattagt gctcaacaaa
     2041 caggattact aaatccatat atattaattg cactattatt atcaattatt tttattatat
     2101 tatttttgat attagaaaaa aaacatcctc aaccgcttct tgaccttgaa atttttagaa
     2161 attttaaatt ttcattgaat ttaatttgtg ctcttacatc attcatttgt attgcatcat
     2221 caagtatttt aattccattt tatttacaaa gtactatgaa acttccccct attcaagcag
     2281 gtttatttat gatactatca cctttgattt tagccatttt ttcacctata tttgggaata
     2341 tatcagataa aattaagtca gaaaaaatta ttttaattgg tcttctcgtt atgagttttg
     2401 gattctttct aatgtcaaga ttgaaagaaa gttctgccct tattttattt gtaatttata
     2461 tatcgataat atcaatagga caagctatat ttcaacctgc taacaatgct ttgataatgt
     2521 caagctgttc tagaagtaag ctaggagttg taggaagcat aaattccctt gtaagaaatt
     2581 taggacaagt tataggtatt actatttcta caacactttt atataatttt atgagtatta
     2641 aagctggata tagggtcaat gattatgtga ttaataatga taaaatattt gtatttggaa
     2701 tgagaaatgt ttatattatt gttacacttg tttgcttaat aggtgcaata ttaattggct
     2761 tttatttatt taaatataat aaaaatgaac aatagttttt ataattatat tcaaattatg
     2821 attatattat aagaaattta ctaaaatact tcctttgagt taaatttaat ttggacatat
     2881 tgacttaaaa atgttttatt aatttgataa aatatttctt ttcctatagt ttataaataa
     2941 aaatcagctg agcaaaatat ttagtatatt atgctcaact gattctttta ttatttaact
     3001 aaaacttcaa tattttcatc ttttccatct ataactatag tacatccatt atacacatct
     3061 ccagcaataa gtttctttgc aattatagtt tctaatgtat ttcctatata tctcttaaga
     3121 ggtcttgctc catatacagg gtcatatcct tctctcacca taacatcttt tgctgaattt
     3181 gtaacttcaa tagtaatatc tttttctttt aatctatttt ttaaatcttt cataaatata
     3241 tctatgattt tcttgatatt ttcttggtct aaaggcttaa acattataat atcatctact
     3301 ctgtttaaaa actcaggttt aaatctatgc ttcatttcat tcattactaa attgttagta
     3361 gtctctgtta tatttcctcc tgcttctaat agataattac ttcctatatt agaagtcatt
     3421 attataagag tatttttaaa gtctactgtc ttacctttat tatcagtaag tctaccatca
     3481 tctaatatct gtaagaacat gttaaataca tcctcatgtg ctttttctat ctcatcaaat
     3541 agtattacag aataaggagc acgtctaact gcttctgtaa gttgaccacc ctcttcatat
     3601 cccacgtacc ctggaggagg tccaactagt cttgatacag catgtttttc catgtattca
     3661 gacatatcta ttcttattat attatcttca ctatcgaata aatttctagc aagagttttt
     3721 gcaagttcag ttttaccaac acctgtaggg cctaagaaaa taaatgaacc aattggtttt
     3781 ctttcatctt ttaatcctgc tcttgcacgt attactgcat ttgaaactgc tgtaactgct
     3841 tcatcttgtc caataactct tttatgaagt tcatcttcta gtttaagtaa tttttctctt
     3901 tctccttcaa ctagtttagt tactggtata cctgtccatt ttgatacaat gctagatatt
     3961 tcttcttcag taacttcttc ttttaaaaga gaattttcag aaccatcatt catattttct
     4021 tcgtactgct ttatttgttc ttctaactta ggtatttcac catatttaac ctctgctgct
     4081 ttgttgaaat catattctct ttcatacttt tcagctttac ctttagcttc gtctaattga
     4141 gcctttaagt ttttaatatc taatatttga ctcttttctt tttcatattt tgctgtcatt
     4201 tcatcatttt tagattttaa ctctgctatt tctttttgaa tatcatccaa tcttgattta
     4261 cttttatcat cattttcttt aagtaatgct tctctttcag tttctaatgt aaataacttt
     4321 cttctaacaa catctaattc tgttggcaat gaatctattt cactacgaat catagctcca
     4381 gcttcatcaa ttaaatcaat tgctttatct ggtaaaaatc tatcttgtat atatctatga
     4441 gaaagttttg ctgctgctac aatagcatta tcatgtattc ttactccatg atgtatctca
     4501 aatctttctt ttaaacctct aagtatagat attgtatctt caacagtagg ttcttctgca
     4561 attacaggct gaaaacgtct ttcaagagcc ttatcttttt ctatatactt tctatattca
     4621 tcaaaagtag ttgcaccaat acagttcaat tcacctcttg caagcatagg tttaataaga
     4681 ttacctgcat ccattgaacc ttctgtttta ccagctccaa caatagtatg aatctcatct
     4741 ataaacagta taatttttcc atcagaactt tgaacttctt ttaaaactgc ctttaatctt
     4801 tcttcaaatt cacctctata ttttgcacca gcaattaaag ctcccatatc aagtgagaat
     4861 acaatcttat cttttaaacc ttctgggacg tctcctctta ctattctctc tgctaaccct
     4921 tctacaattg cagttttacc tacacctggc tcaccaatca atacaggatt attttttgtt
     4981 cttcttgata aaattcttat aatccttctt atttcttcat ctctcccaat tacagggtct
     5041 aatttatttt tcttggctaa atctactaag tttgttccat atctagcaag tgcatcatat
     5101 gtgccttctg ggtcttgtgt ttctactctt tgactacctc tcacttgtga taaaatattt
     5161 aaaaagtcat tcttatttat attatattgt tttaatattt taccaacagc tgattttgat
     5221 tctgtttcca tcattgcaag cataacatgc tctacactta tatatgaatc tttaaattct
     5281 ttagaaatac tctctgcctt tataagcacc tcatttattt ttctagtagc tgatactcct
     5341 tgtgagtcag caccttctcc atatactttt ggaagcttat caatttcaaa gtttacagta
     5401 tttctcaaag aatcaattga tatattcatt ttttcgatta tatttggtat caatccatcc
     5461 tcttgattaa taagtgctga gaaaagatga attacatcta cttgttggtt atgatttttt
     5521 actgcttcgt tataagcctc atttaaactt ttttgaactc ttaaagtcat tttttctacg
     5581 tccatataaa tccctccatt ttaatattat atccaaataa attaaattct ctcatttata
     5641 attattgatt ttctaagctc taaaagacta tcaagtaaat tctcgttttt ttgtatatcg
     5701 aaactcaatg ttaaattaaa tgttccatct gaattaaaaa aatcgaatac ttcttttgat
     5761 tttgctatta aatacaagtc ttcatctata agtctttttt cacctattaa taaatactga
     5821 catttatcta taaaactctt tttaaaatca atagtgtata gattttctaa aatattatat
     5881 tgataaatag caatattatt aaacactttt aatatgtttg aatttacaaa attgtaaatt
     5941 tgattattgt tatacagtga tatttgttcg tatatatatt ccctaaataa aggatgaatg
     6001 ttttgcttaa gttttaaagt aacttcagct ggtatttcaa aataaagctt ccagtactta
     6061 gagttatttt tttctaaaat aaaagctact ttgttcaaac tggtagaact aatctccttt
     6121 agtgtacaat taaaattata gtgtctcaaa ctagtttttt cattctcaaa tacatagtca
     6181 aaccactgta gaacatttct atcaagtttt aaactcatat aaaaaccttc ttccttattt
     6241 actaacctta ttaggtcttt ttatctgatt atattctgct aataaacttt ctttatcagc
     6301 tctactacct ttatatgcta tatgtggatt tatcatatac tcaccatttt tcactctttg
     6361 taaaaaatcc atttttttca gctccgtaaa caatgaagat aaagaagttt ttggatattc
     6421 aaattcacaa gataattcat ataatgtttt tctaatctta ttatttttat ccatagagtt
     6481 tattaatttt aatggaatta aatccctctt agtatacatt ccttctacta ctttaatata
     6541 attcttaaaa caaacattca tatacttact tttattcata actaaacttt tgctctctgt
     6601 atattcctga tttaaatcct tttttaatgt cttatccaaa ttaaatatct cttctcactc
     6661 tccttatctc taattgataa tataaatata ttacaaaaaa atatgtatgt caaaactaaa
     6721 aatgcaaaaa gtttacctta taagtaaact tttatttagc tataagctaa actttattat
     6781 ttttttaatt tagtatttcc aatttattgg caggattttt gaacaatatt tataaatttt
     6841 ttaaaaaaat ttatatctat ttaatatggc agactttcat aaaatacatt acatttatta
     6901 aatgtataat attggcaatt agttttttct aaaatcagtt gacatattat atatatattt
     6961 atataatgtg tatatactat atatacaatt taaggaggtg tcttattgaa tatagttatt
     7021 agtaattcga gtgggaagcc aatatatgaa cagattacta cacaaattaa aagtatgatt
     7081 ataagtggag agttaccaga aggctcagct cttccaagta tgagactatt ggcaaaagaa
     7141 cttagaataa gtgtaattac tacaaaacga gcatatagcg atttagaacg agacggattt
     7201 attgagacag ttactggtaa aggcagtttt gtatctagta aaaacatgga ttttgtcaaa
     7261 gaagaacaat ttcgtttaat tgaagaatac ctacaaaaag cagttgatac agcaaaaagt
     7321 agtgatatta catatgacga attaaaagat attttatttt tattatataa aggagaatga
     7381 taagtatgga tgcaataact ataaaaaatt taaataaaac ttataaagat tttagcctac
     7441 aagatatatc tttttcagta ccaaaaggga gtgtaatggg atttgtaggt gaaaatggtg
     7501 caggaaaaac aactacatta aaagcaattt taaatttaat atcttatgat agtggaaata
     7561 tagaaatctt tggtcttgat agtaaaaaaa atgaaaaaga aattaaagag caaattgggg
     7621 ttgtatttga gggaagcaac tttcatgaaa atttaaacac tgaccatgtt tcaaaaatca
     7681 tgagtaaaat ctataaaaat tggaatgaca cattatttaa agactactta aaaaaattga
     7741 gagtaccaga caataaatta attaaggagt tttcaaaggg gaataagatg aaacttagta
     7801 ttgctgtagc cttatctcat aaaccaaaat tattaatact agatgaggca actagttcac
     7861 ttgaccctat cgttcgtgaa gaaatactag atatattttt agattttata caagatgaag
     7921 aacactctat tatcttatct tcacatatta caagtgattt agataagata gcagactata
     7981 ttacatttat acataaagga aaaattgtat ttagtgaaaa taaggatgaa ttaattgata
     8041 ctatgggagt tttaaaatgt aaacctagtg attttgataa cctttcaaga gaggattatt
     8101 catattatcg taaaagccaa tttggatatg aagtacttct taaagataag catagattta
     8161 tctcaagaca tccaaactgt attgttgata atacgtctat agaagaaatt atgttatttt
     8221 atgtgagagg tgataaataa tgaaaggtct aattttaaaa gatttactta atttgaaagg
     8281 aaatataaag tttatacttt tattcatcat tatgtttggc tttatgtctt ctttaggaga
     8341 tggaaatgtt aataacttta taggtgttat tatagtttta tgtactacaa tgattgtttc
     8401 aacattttca tatgatgatt tgaataaatg ggatagttat gtacttacaa tgcctattaa
     8461 tcgcaatgat attgtattaa gtaaatattt aactatgtta atatttagct ttataggtgt
     8521 tcttgtttca cttattgtta gtgtaactat tggttatttt aaaaatacac ttatattaaa
     8581 tgaaacacta cttattaatg cactaatctt atcaatttca gtatgttttg gtagccttat
     8641 tctaccactt atttataaat ttggtacaga aagagctcgt ttattaatga ttttatgctt
     8701 tttagttcca acactagctt tattagtttt taaaagtatt ttagaaaata ttagttcacc
     8761 tatttctata gaaattatac ttaatacact agtatattct cttccatttg ttgctatttt
     8821 actatttgtg atttcatatt ttatatcatc aaaaatctat agtaaaaaag aagtat
//
LOCUS       DAMKNB010000116         8875 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.122, whole genome shotgun sequence.
ACCESSION   DAMKNB010000116 DAMKNB010000000
VERSION     DAMKNB010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8875)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8875)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8875
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.122"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            54..620
                     /locus_tag="PC494_003288"
     CDS             54..620
                     /locus_tag="PC494_003288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase"
                     /protein_id="HDF3913759.1"
                     /translation="MRKLEEILEYNKSFVENKEYEQYVTSKHPNKKIVVLSCMDTRLT
                     ELLPKAMNLKNGDVKLIKNAGATIMHPFGSIMRSVLVAIYEFDVDEVMVVGHHGCGMC
                     NVDTDKLLGKILDRGISNDVILTLRSAGIDTKQWLHGFDSAEESVKDSIDLIKGHPLI
                     PDGIIVHGLIISPETGKLDVVVNGYEDK"
     gene            925..1386
                     /locus_tag="PC494_003289"
     CDS             925..1386
                     /locus_tag="PC494_003289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HDF3913760.1"
                     /translation="MNSNSEEKLNDVFLQLMRIYFIRTHFYFDKLGLYHGQPQILFSL
                     KMKDGQSQKELADKRKVKASTTTVMIKRMEKAGLVERKQDEKDQRVSRIFLTDKGLEI
                     CNKVEEFNKELEREFFLGFSEEEKIVLRRLLMQVRDNLKAGCHKHEDEKYF"
     gene            1454..3700
                     /locus_tag="PC494_003290"
     CDS             1454..3700
                     /locus_tag="PC494_003290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011009877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF3913761.1"
                     /translation="MFKLIKYLKKSALSIVIIVCLLVIQAVCDLSLPEYTSNIVNVGI
                     QQGGVENSVPSVIRESELNKITLFMDKSSKDKVLDNYTLLNKKDYVKYKDKYPGLKDE
                     SLYELNTKDKDTIDDLNVIFGKAILIVSGLEGDSKEVKAMKAQLMSKLPPQATQSGDV
                     DIFKLLSAMPKEQLDTLTKEMSKGFESMPESMITQSSVSYVRSEYEKIGIDTEKTQNN
                     YILFTGAKMLGIAMISMVATITVGFLAARVAASVGRNLRSGVFRKVMSFSNTEMNEFS
                     TASLITRSTNDIQQIQMLMVMLLRIVFYAPIMAIGGVIKVLNTNTSMAWIIAVAVVAI
                     LSLIVVLFSVVMPKFKLVQKLVDKLNLVSREIITGIPVIRAFSTEKHEEERFDKANKN
                     LTKTNLFVNRVMTCMMPAMMLIMNLITVLIVWRGAYSVDSGAMQVGDMMAFIQYTMQI
                     IMSFLMISMVSIMLPRASVSATRIDEVLVSDISIKDPEKSEAQEFKEDKKGLVEFKNV
                     SFMYPDAEEPILTNISFTAKPGETTAFIGSTGSGKSTLINLIPRFFDVTEGEILLGGV
                     NIKNVSQHDLREKIGYVPQKGVLFSGTIESNLKYGRKDATDEEMRTAAEIAQATEFID
                     SKPEAFKTEISQGGTNVSGGQKQRLSIARAIAKNPEVYIFDDSFSALDLKTDAALRKA
                     LKSKTAESTVLIVAQRISTILNAEQIIVLNEGEIVGIGTHKELLKNCEVYEQIALSQL
                     SKEELANE"
     gene            3693..5525
                     /locus_tag="PC494_003291"
     CDS             3693..5525
                     /locus_tag="PC494_003291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF3913762.1"
                     /translation="MSRMGRGPMGKSMGAGQKANDFKGTMRKLIAYLSKFKISIILVI
                     VFAIGSASFSIVGPKILGKATTKIFEGLVSKVSGGNVGIDFNAIGKILTFLLFLYLIS
                     ALFSFIQGFIMSGISQKVSYNLRKEISAKLDRLPMKYFDTKTHGEILSRITNDIDTLN
                     QSLNQSMTQLITSVTTMIGVLIMMLSISGIMTLVAVLILPISMFVISRIIKKSQKYFR
                     YQQEYLGNVNGQVEETYSGQTIVKAFNREDEVIEEFDKLNDSLYNSAWKSQFLSGIMQ
                     PLMMFIGNLGYVMVSILGGWLAIKKTIEVGDIQSFIQYVRNFTQPMTQIAQVANLLQS
                     TAAASERVFEFLEEEEEVQIVENAVSIDGLEGKIDFENVNFGYNPNKTIINDFSVNVK
                     PGQKVAIVGPTGAGKTTIVKLLMRFYDVNSGSILIDGHNIKDFNRSELREMFGMVLQD
                     TWLFSGSIMENIRYGKLNATDEEVIEAAKSAHVHRFIKTLPDGYKMKLNEEASNVSQG
                     QKQLLTIARAILADPKILILDEATSSVDTRTEVLIQKAMDNLMEGRTSFVIAHRLSTI
                     RDADMILVMNEGDIVEQGNHEELLKKGGFYANLYNSQFEEDEAM"
     gene            6244..7521
                     /gene="hflX"
                     /locus_tag="PC494_003292"
     CDS             6244..7521
                     /gene="hflX"
                     /locus_tag="PC494_003292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HDF3913763.1"
                     /translation="MDMAKKGITVGLNINNKSEDFNELMIELENLCSACDIDVVGSIT
                     QNAKQVNRAFYIGTGKVEEILNLIKKENIEIVIFYNELSTSQLKNLEEKLNCEIIDRT
                     ALILDIFAQRAKTREAKLQVELASLKYMLPRLIGSNENLGRQSGGVGTKNRGSGEKKL
                     ELDRRRIEEKITSLNRELDDLKFQRETQRSMRRKSNLPNVALVGYTNAGKSSIMNKLV
                     DIFKNSEEKKVFEKNMLFATLETSVRNIVLANNKEFLLSDTVGFVSNLPHDLVKAFRS
                     TLEEACEADVLLHVIDISNPSYKSHIKVTEDTLKQIGADGIPMIHVYNKIDLIDVEVL
                     DRILDSIDKEGIFVSVKKDINIDKMIKCICDSIFKDYVRYKFLIPYDKGHVVSYFNEN
                     TSIINTEYREDGAILDVECSNIEYNKYKKYALE"
     gene            7754..8251
                     /locus_tag="PC494_003293"
     CDS             7754..8251
                     /locus_tag="PC494_003293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HDF3913764.1"
                     /translation="MDAESLMKKYMVDDDSRKQAIFASIFVMQNKLQTTCDKLDPELT
                     MKQWLLLAIADSVDETLTLTKLGELMGCSRQNVKKLAIALEKKGFIEIEQNEKDSRAI
                     CLVTKDRVQEYSKKVRGMQEKVLQLLFEDFTEKEAEQLFFGIMKLSIGIENVKNYVEN
                     NDVGE"
     gene            8300..8824
                     /locus_tag="PC494_003294"
     CDS             8300..8824
                     /locus_tag="PC494_003294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HDF3913765.1"
                     /translation="MKSVVVIYKSKYGSTKKYAKWLSELLSCDIFETKNINIEKVMKY
                     DTIILGGGLYACNIAGISFLKKNYKELKKKNLVVFGVGAAPYDDEVIKKLREVNFKDE
                     LNKIPCFYCRGAWDETKMSFIDYTLCSFFKKSIAKKERQGLKPAEAPLLSGEAFDWCN
                     KENLTPILDYIREL"
BASE COUNT         3511 a          896 c         1618 g         2850 t
ORIGIN      
        1 actttaatag tgatataata ataaaaaaat ttttaaagag ggtgatatta catatgagaa
       61 aacttgaaga gatattagaa tataataaat catttgtaga gaacaaagaa tatgaacaat
      121 atgtgacatc aaaacatcca aataaaaaaa tagtagtctt atcttgtatg gatacaagat
      181 taactgagct tttgcctaag gctatgaatt tgaaaaatgg agatgtgaaa ctaataaaaa
      241 atgcaggagc tactataatg catccttttg gaagtattat gagaagtgtt ttagttgcaa
      301 tttacgaatt tgatgtagat gaggttatgg ttgtagggca tcatggatgt ggtatgtgta
      361 atgttgatac ggataagtta cttggtaaaa ttttagatag aggaatatct aatgatgtaa
      421 tacttacact tcgtagtgct ggaattgata caaaacaatg gttacatgga ttcgattctg
      481 cagaagaatc tgtaaaagat agtattgatt taataaaagg gcatccttta attccagatg
      541 gtattattgt acatggtcta attatatcac ctgaaactgg gaagttagac gttgttgtaa
      601 atggatatga agataagtag agtatcataa tgttatataa tcaagatact gttgaatatg
      661 atgttgtttc aaaatttatt ttgggacaac ttttttattt gaaaatatat gaaaaggttt
      721 attttaagct ttgcaataaa aaatataagt agctgactaa ttaaaaatct tactattatt
      781 tattaaaatt ataactatat gatataaaaa tatttaataa atgaaattta tatgaatttt
      841 ttataaatat attgaaaaaa tgcatgcagt atagtaaaat aatacttagc tgactaagta
      901 atataaaaaa taaggagggc aagtatgaat agcaattctg aagaaaaatt aaatgatgtt
      961 ttcttgcaat taatgcgaat atattttata agaactcatt tttattttga taaattaggc
     1021 ttatatcatg gtcaacccca aatacttttt tctttaaaga tgaaagatgg gcaaagtcaa
     1081 aaagaattag cagataaaag gaaagtaaaa gcatctacaa ctacagttat gataaagagg
     1141 atggaaaaag ctggacttgt ggaaagaaaa caagatgaaa aggaccaaag agtatctagg
     1201 atttttttga cagacaaagg tttagaaata tgtaataaag ttgaagaatt taacaaggaa
     1261 ttggaaagag agtttttttt aggatttagt gaagaagaaa aaatagtact tagaagactt
     1321 ctaatgcaag tacgagataa tttaaaagca ggatgtcata agcatgaaga tgaaaaatat
     1381 ttttaaagtt taaaataatg tttttcaatt taatgttatt agactaatta atattacaga
     1441 agggaagaaa tgtatgttta aattaattaa atatttaaag aaatcggcat tatcaatagt
     1501 aataatagtc tgtctattgg taattcaagc ggtatgtgac ctttctttac cagaatacac
     1561 atccaatata gtaaatgtag gtatacaaca aggtggagta gaaaactctg ttccatctgt
     1621 gattagagag agtgaattaa ataaaattac tttatttatg gataaaagta gtaaggataa
     1681 agtactagat aattatactt tgctgaataa aaaggattat gttaagtata aagataagta
     1741 cccaggtcta aaagatgaat ctctttatga gttaaatact aaagacaaag acactataga
     1801 tgatttaaat gttatttttg gtaaagctat tttaatagta tcagggcttg agggcgatag
     1861 taaagaggta aaagctatga aagctcagtt aatgagcaaa cttccaccac aagctactca
     1921 aagtggagat gttgatatat ttaaattgtt atcagcaatg ccaaaggaac agttagatac
     1981 attgactaaa gagatgagca aaggctttga aagtatgcca gagagtatga taacacaaag
     2041 ctctgtttca tatgtaaggt cagaatatga gaaaataggt attgatacag aaaaaactca
     2101 aaataattat atattattta ctggtgctaa aatgcttggt atagcaatga ttagtatggt
     2161 agctacaata acagtaggat ttttagcagc aagagtagca gcaagtgtag gtagaaattt
     2221 aagaagtgga gtatttagaa aagttatgtc attttcaaat actgaaatga atgaattttc
     2281 tacagcttca ttaattactc gtagtacaaa tgatattcaa cagatacaaa tgttgatggt
     2341 tatgttgctt agaatagtat tctatgcacc tataatggct ataggtggag tgataaaggt
     2401 tttaaacaca aatacttcaa tggcctggat tatagcagta gcagtagttg ctatcttatc
     2461 attaattgta gtgttattct cagtggttat gcctaagttt aaactggttc aaaagcttgt
     2521 tgataagtta aacttagtaa gccgtgaaat aattactggt attccagtta tcagagcttt
     2581 tagtactgaa aaacatgaag aagaaagatt tgataaagca aataaaaatt taactaaaac
     2641 aaatcttttt gtaaatagag ttatgacatg tatgatgcct gctatgatgc ttataatgaa
     2701 ccttatcaca gttcttatag tttggagagg tgcatacagt gttgattctg gagcaatgca
     2761 agttggagat atgatggcat ttatacaata tacaatgcaa ataataatgt cattcttaat
     2821 gatatcaatg gtatctatta tgcttccaag agcatccgtt tcagctacac gtatagatga
     2881 agtattagtg tcagatataa gcataaaaga cccagaaaaa tcagaggcac aagagtttaa
     2941 ggaagataaa aagggtcttg ttgaatttaa aaatgtttcg ttcatgtatc cagacgcaga
     3001 agaacctata ttaacaaata tatcttttac agcaaagcca ggagaaacaa ctgcctttat
     3061 aggaagtact ggtagtggta agtcaactct tataaattta attcctcgtt tctttgatgt
     3121 tactgaagga gaaatattac ttggtggagt taatataaaa aatgtttctc aacatgattt
     3181 aagggaaaaa attggatatg tacctcaaaa gggagtattg ttttctggta ctatagaatc
     3241 caacttaaaa tatggtagaa aagacgcaac agatgaagaa atgagaacag cagctgaaat
     3301 agctcaagct acagaattta tagattctaa accggaagct tttaaaactg aaatttctca
     3361 aggtggaaca aatgtatctg gaggtcaaaa acaaagactt tctattgcaa gagcaatagc
     3421 aaaaaatcca gaagtttata tatttgatga tagtttttca gcacttgact taaaaactga
     3481 tgcagctctt cgtaaggctt taaaatcaaa aactgctgaa agtacagttc taatagttgc
     3541 acaaagaatt agtactatct taaatgcaga acagataatt gttttaaatg agggcgaaat
     3601 agttggaata ggaacacata aagagcttct aaaaaattgc gaagtttatg agcaaatagc
     3661 tttatcacaa ctttcaaagg aggagctagc taatgagtag aatgggaaga ggtcctatgg
     3721 gaaaatctat gggagcagga caaaaagcaa atgactttaa agggactatg cgaaaactaa
     3781 ttgcatattt atctaaattt aaaatatcaa taattctagt aattgtattt gctattggta
     3841 gtgcgtcgtt ttctatagta ggtccaaaaa ttttaggaaa ggcaactaca aagatatttg
     3901 aagggctagt gagtaaagtt tctggaggaa acgtaggtat agattttaat gcaattggaa
     3961 aaatcttaac ctttttactt ttcctttatt tgataagtgc actgttctct tttatacaag
     4021 gatttataat gagtggaatt tctcaaaaag tatcctataa tttaagaaaa gagatttcag
     4081 caaaattgga tagattgcca atgaagtatt ttgatactaa gacgcatggt gaaatattat
     4141 cgagaattac gaatgatata gatactttaa atcaaagttt aaatcaaagt atgacacagc
     4201 ttataacatc agtaacaact atgataggtg ttttgataat gatgttatct ataagtggaa
     4261 ttatgacatt agtggcagtt ttaatattac caatatcaat gtttgtaatt tcaagaataa
     4321 taaagaaatc acaaaaatac tttagatatc aacaagaata tttaggaaat gtaaatggtc
     4381 aagttgagga aacttacagt ggccaaacaa tagtaaaagc atttaatcgt gaggatgaag
     4441 taattgaaga gtttgataaa ctaaatgata gcctgtataa ttcagcgtgg aaatctcaat
     4501 ttttatcagg tataatgcaa ccacttatga tgtttattgg aaacttggga tatgtaatgg
     4561 tatcaatctt aggaggttgg cttgcaatta agaaaacaat tgaggttggt gacatacagt
     4621 catttataca atatgtaaga aactttacac agccaatgac tcagattgca caggttgcca
     4681 atttattgca atcaacagca gcagcttctg aaagagtatt tgagttttta gaagaggaag
     4741 aagaagtcca aattgttgaa aatgcagttt caatagatgg tttagaaggt aaaattgatt
     4801 ttgaaaatgt caactttgga tataacccaa acaagactat aataaatgat ttctcagtaa
     4861 atgttaaacc tggtcaaaaa gttgctattg ttggacctac aggagcaggt aaaactacaa
     4921 tagttaaact gttaatgaga ttttatgatg ttaatagcgg ttcaatactg attgatggtc
     4981 ataatattaa agattttaat cgtagtgagc ttagagaaat gtttggtatg gttcttcaag
     5041 atacatggtt atttagtggt tcaattatgg aaaatataag atatggtaag ttgaatgcta
     5101 cagatgaaga agttatagag gctgctaaat ctgcacatgt tcatagattt attaagacat
     5161 taccagatgg atataagatg aaattaaatg aagaagcaag taatgtttct caaggtcaaa
     5221 aacaattatt gactatagct cgtgctattt tagctgatcc taaaatttta atattagatg
     5281 aagctacaag ttctgtcgat actagaacag aagtattgat tcaaaaagct atggataatc
     5341 ttatggaagg tagaacaagt tttgttatag cccacagatt atcaactata cgtgatgctg
     5401 atatgattct tgtaatgaat gaaggagata tagttgaaca aggaaatcat gaggaacttc
     5461 taaagaaagg cggattctat gccaatcttt acaattctca atttgaagaa gatgaagcaa
     5521 tgtaacaaaa aactatctta gcatagacat gtaattaata agataaaata aatgagggtg
     5581 ccttaaaatg aactttttaa ttcataaggc actcttttgt gtatgaaata aagtgtattt
     5641 ttatcatttt aacaatgaaa aagaggattc tctatatttt gagatagcca cataatttta
     5701 tgtctttaca aagtgtttat tttattataa tatgtagtaa ggaaaatgtt ggaggtgatt
     5761 atcaaaatgt atatttaatt ttattcttta aattttatta taaatagaat ttaattttaa
     5821 tagttgatga ttatattgaa gtatatgttt ttattacttt tattaatcat gcaaataact
     5881 acttaaattt aagaataggg ttaaatataa aatgataatt acatataagt taattaaact
     5941 aatgtatttt taatatatat ttagaatttt aatccttctt atgatataag tagcttgttt
     6001 tgtattactt agatttgtaa ggagtttttt tattgaaaaa actgcataat atatttggga
     6061 ggaggtgtaa gaaagtgatt ttttatataa gattgagaaa ataatgcacg attatggtta
     6121 ttataatagt aaataagaag tgtcatttaa ggataagata aaaagcaaaa ttcttgatga
     6181 atttaattat agagccataa tctcgtgcta tagattaaat aaaaaatagc agataaggag
     6241 aatatggata tggcgaaaaa aggaataaca gtaggattaa acataaataa taaatctgag
     6301 gactttaatg aactaatgat tgaacttgaa aacttatgtt cagcatgtga tattgatgtt
     6361 gtagggagta taactcaaaa tgcaaagcag gttaatagag cattttacat tgggacaggt
     6421 aaagttgagg aaatattaaa cttaataaag aaagaaaata tagagatagt tatattttac
     6481 aatgaacttt ctacatcaca actaaaaaat cttgaagaaa agcttaattg tgaaattata
     6541 gatagaacgg cattgatact tgatatattt gcacaaaggg caaaaactag agaagctaaa
     6601 cttcaagtag aattagcaag tttaaaatat atgttaccaa gacttatagg ttcaaatgaa
     6661 aatttaggac gtcaaagtgg tggagttggt actaaaaata gaggttctgg tgagaaaaaa
     6721 ttagaacttg accgtagaag aatagaagaa aagataacat ctttaaatag ggagttggat
     6781 gatttaaaat tccaaagaga aactcaaaga agtatgagaa gaaaatcaaa tcttccaaat
     6841 gtagctctag ttgggtatac aaatgctggt aaatcttcaa taatgaataa actagtagat
     6901 atatttaaaa actctgaaga aaagaaagtg tttgagaaaa acatgttatt tgctacactt
     6961 gaaacttctg tcagaaatat agttcttgca aataacaaag aatttttatt atctgatact
     7021 gttggttttg taagtaatct accacatgat ttagtaaaag catttaggtc aacattagaa
     7081 gaagcatgtg aggcagacgt actgttacat gttattgata tttcaaatcc aagctataaa
     7141 agtcatatta aagtgacaga agatacttta aaacaaatag gtgcagatgg tatacctatg
     7201 atacatgtgt ataataaaat tgatttaata gatgtagaag tattggatag aattttagat
     7261 agtatcgata aagaaggtat atttgtttca gttaaaaaag atataaatat agataaaatg
     7321 ataaaatgta tttgtgatag catatttaaa gattatgtaa gatataagtt cttaattcca
     7381 tatgataaag gtcatgtagt ttcttatttt aacgaaaata cgagcattat aaatacagaa
     7441 tacagagaag atggagctat tttagatgta gaatgtagca atatagaata taataagtat
     7501 aaaaagtatg ctttagagta aattttgaaa aacttattat agcctaaaat atatttaatt
     7561 tataatttat tataaattga ttgtaaatat gattttatga aacggtatag ccataatgct
     7621 atgccgtttt gccatttata ataaaaataa atttattgac ataatagtaa ctaattacta
     7681 taatataaag taattagtta ctatttaaaa ttatcaaaaa attaaaatct aagataaaga
     7741 gaagtgtata ataatggatg cagaaagttt aatgaaaaaa tatatggtag atgatgatag
     7801 tagaaaacaa gctatatttg caagtatatt tgtaatgcaa aataaacttc aaactacatg
     7861 tgataaatta gacccagaat taacaatgaa acaatggtta cttttagcta ttgcggactc
     7921 tgtagatgaa actcttacat taaccaaact tggagaatta atggggtgtt caagacaaaa
     7981 tgtaaaaaaa ctagctattg ctttagaaaa gaaaggtttt atagaaattg agcaaaatga
     8041 aaaagattca agagctatct gtcttgtgac aaaagataga gtgcaagagt attctaaaaa
     8101 agtgagaggt atgcaggaaa aagtattaca gcttttattt gaagatttta cagagaaaga
     8161 agcggaacag ttattttttg gaattatgaa attaagtata ggaattgaaa atgtgaaaaa
     8221 ttatgtagaa aataatgacg ttggagaata agcaagtatc aaatcaactt tgtatgacat
     8281 cagagagggg agaatttata tgaaaagtgt agtagtgatt tataagagta agtatggttc
     8341 aacaaaaaaa tatgctaaat ggctttcaga attattgtct tgtgatattt ttgaaactaa
     8401 gaatattaat atagaaaagg ttatgaagta tgatacgatt attttaggag gaggtcttta
     8461 tgcttgtaat atagcgggaa tttctttctt aaaaaaaaat tataaagaat tgaagaaaaa
     8521 aaatttagta gtatttggcg taggagctgc tccatatgat gatgaagtaa taaagaaatt
     8581 aagagaagta aactttaagg atgaattaaa caaaattcct tgcttttatt gtcgtggggc
     8641 atgggatgag acaaaaatgt cttttataga ttatactctt tgtagttttt ttaaaaaatc
     8701 tatagctaaa aaagaacgtc aaggtcttaa accagcagaa gcacctttat tgtctggaga
     8761 agcctttgat tggtgtaata aagaaaattt aactccaata cttgattata taagagaact
     8821 ttaagaggta tatatttgta attatttatt atctaaagtt agatttcata gaaat
//
LOCUS       DAMKNB010000117         8853 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.123, whole genome shotgun sequence.
ACCESSION   DAMKNB010000117 DAMKNB010000000
VERSION     DAMKNB010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8853)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8853)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8853
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.123"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            212..1540
                     /locus_tag="PC494_003295"
     CDS             212..1540
                     /locus_tag="PC494_003295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HDF3913766.1"
                     /translation="MGSNELKKTLGVSAALSTVVGSVIGAGVFFKPQAVYTLTGGAPG
                     LGILAWLIAGIITITAGLTAAEVSVAIPKTGGMMVYIKEIYGEKLGFLTGWMQIVLFY
                     PGMMAALGVIFGEQASALIGSPSLLLPIAIGIIVIVAGLNMLGSKTGGVIQTVSTICK
                     LIPLILIMVVGFIKGGGNNPILTPMVGEGLSLGSVLGQVLIAILFAFDGWMNVGTLAG
                     EMKNPGKDLPKAIIGGLSVVMAVYFIINLAYLWVLPANELANYASPASAVAEVIFGSM
                     GGKIISVGILISVFGALNGFLLTGSRVAYTLATDKTLPKYGIFSKLNSAQVPANAIAL
                     VSVIASIYALSGQFNLLTDLAVFATWIFYVLTFIGVMKLRKTHPNIPREYKVPLYPIV
                     PIIAIASGIFVVVNQLCFAGMKTTMISIGGLVITAIGLPVYAYMTRGVKR"
     gene            2293..3126
                     /locus_tag="PC494_003296"
     CDS             2293..3126
                     /locus_tag="PC494_003296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase"
                     /protein_id="HDF3913767.1"
                     /translation="MRNKKKKINRKKLYLLLSAIVVCLAFIVVGVRVSSLNMKENEIS
                     RNAKLSSSTITDIVSNTSIEVSKGPSKSSGKIAYITIDDGPSKFTDEMIKTLNKYNVK
                     ATFFMIDGNMKEYPQQVKNIIKNGNTAGFHSVSHDIHKLYVTSTSAKEEFDTNDQTFY
                     KITGKHSKVIRIPYGSKPYTPQASYQALVDAGYKIWDWDLDTEDWRSNSSQIVQNVKN
                     HIKNRKGEDKDQLVVLMHEKKQSAEALDSVLKFLSDEGYEFAPVDQNQIPKNYWLRNL
                     E"
     gene            3219..4151
                     /locus_tag="PC494_003297"
     CDS             3219..4151
                     /locus_tag="PC494_003297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HDF3913768.1"
                     /translation="MVGILSLMMVGCNKSLAKVNDVEITKEQYKKTKAVLSATNNYIN
                     GQSLDELEKTLDKKGRNKLENVIISFMVDNELLYQEAKDKGLTPSKSEVDSKYQELED
                     KMNLNTSYKEKMDKAGVDKDYLKQEISRDLAIDKNKKAFEDRINISDNDMEAYYTSHK
                     KDFNVEEVSASQILISTLDKNKKEVSKDKKEALKKKADNILTKIKNGESFESLAKKYS
                     DDKATGKNGGQLGYFTKDDKNAEFTKEVFKLKKNEVSNVFETSYGYHIVKVTDKRERQ
                     KSFNECQSLIRESILNEKYIEHIKKLNEDAKIDR"
     gene            4203..4685
                     /locus_tag="PC494_003298"
     CDS             4203..4685
                     /locus_tag="PC494_003298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HDF3913769.1"
                     /translation="MFKSLKRTKVEKYIIDNKDSFYRIAYSYTKNEEDALDVVQEAMY
                     KALYSVENIKEVNYIKTWFYKILVRTSIDFIRKNRKYNNMTDIDLIDETGEYDKYTDL
                     DLRRALEELPIEYKSIIILRFFEDLKIEEVAIILDENVNTVKTRLYTALKKLKLKIEE
                     "
     gene            4697..5566
                     /locus_tag="PC494_003299"
     CDS             4697..5566
                     /locus_tag="PC494_003299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3298 domain-containing protein"
                     /protein_id="HDF3913770.1"
                     /translation="MTSKERLNKLKDEYHKIPIPKKLDTIINHEKIENIYREKNKKVN
                     RLRFKVAIAFACIFTVLVNISPVFADNFSKIPVIGAIVEVITIKNYSLKSENYEAEID
                     IPKIRGLKDKNLEQRLNSSFMEDGKRLYHQFQERMEKIQSSKNKGYKSLSLSYSVKNN
                     SKKFLSIEMTKNEIEASSYVSKVHYTIDKKRQIVLTLPMLFKDDKYIKVISDNIKEQM
                     REQMKKDSTKSYFIDQKKDLPVEDFKTINKYQDFYFNKNEDLVICFDEYEVAPGYMGA
                     VEFVIPYKVIKDL"
     gene            5609..6364
                     /locus_tag="PC494_003300"
     CDS             5609..6364
                     /locus_tag="PC494_003300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3298 domain-containing protein"
                     /protein_id="HDF3913771.1"
                     /translation="MTTYKKLKKSIFKIAIFSICLLVSLVDTNPIFAGSSFNETSNSD
                     TIKVLNTKSINFKQDNYEVNVSIPKIKGLKDKTLENKLNNEFLQDGKKIYSEFQNKMK
                     KEDNKGHRYLNVIHNVKNNSKDFLSIEMTKEEIEASSSITKKHYTVDKNRGILLNLPI
                     FFKDSRYIRAISDNIKEQMRNQIKKDDTKSYFIDQDKDSPVKDFESINKYQDFYFNKN
                     GNLVISFDEYEVAPGYMGAVEFVIPNKVIKRLR"
     gene            6406..7227
                     /locus_tag="PC494_003301"
     CDS             6406..7227
                     /locus_tag="PC494_003301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XdhC family protein"
                     /protein_id="HDF3913772.1"
                     /translation="MNIYEQAIRLIENNEDFAFATITSHSGSTPRETGAMMIVKNDST
                     IFGSVGGGSVEAECIKHAINVIKNRESMLYKFTLNKSDVAKLGMICGGTGEIQIDFID
                     SKLKSNIEKFNKRLKENTSKAYIFGAGHISRDVAVILSLLEFRTVVIDDREEFANHER
                     FPESEVVVLDSFENIPDFPTDKNSYIIILTRGHLYDSSALEWALKREAGYIGMIGSRT
                     KIGLTYEKLMKKGFKKEELSKVHAPIGIKLNAQTPAEIAVCIAAELINCRANKEK"
     gene            7232..7993
                     /locus_tag="PC494_003302"
     CDS             7232..7993
                     /locus_tag="PC494_003302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M48 family metallopeptidase"
                     /protein_id="HDF3913773.1"
                     /translation="MNTGSKDIDTLKVNFRGIEIKAVLVYKNRKNISIKIDPFGKITV
                     MSPPKISKKIIKDIIIEKGDWILKKSEKCKGREEVYKQRMFITGEKFLYLGEEYHLVI
                     KELLRDSVKKSNCRITINEYQIVVQTNDTSTDFIKKSLKSWYKMESERIVLERIDFLK
                     LNCEIMKQLVPASVKVKEQNKRWGSCTAQKNIYINSKISMARLDVIDYVIIHEFSHLV
                     HMNHSKKFYDLVKSIMPDYKDKENWLKINGYKIII"
     misc_binding    8154..8411
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            8524..8763
                     /locus_tag="PC494_003303"
     CDS             8524..8763
                     /locus_tag="PC494_003303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HDF3913774.1"
                     /translation="MENTVYAKLNQGIDSFLRVAMTLRRREVDIQSISMTVDNMNNSG
                     IKLIVNEEKTSLDSVLNHMKKLHDIREITVERMRH"
BASE COUNT         3722 a          848 c         1503 g         2780 t
ORIGIN      
        1 atacatttac ttagaagtat tattatattt ggatttttgg tttttataat ttttttatat
       61 ttaaacataa ctaaaaataa aagattacta aagctaagta gagtttattt tattttaata
      121 aataataaag ctatttttct atatattggc ataatatatg cttatttaac tatgaaatta
      181 aaattaaata ggattaatga ggaggaaaaa aatgggaagt aatgaactaa aaaagactct
      241 tggcgtatca gcagcattat caactgttgt tggttccgtt ataggagcgg gcgtattttt
      301 taaaccacaa gcagtctata cattaactgg aggagctcca ggtcttggta tattggcatg
      361 gttaatagct ggaatcataa ctataacagc tggtcttaca gctgcagagg tatcagttgc
      421 gataccaaaa actggtggaa tgatggtata tataaaagaa atttatggag aaaaattagg
      481 ttttttaact ggatggatgc aaattgtatt attttatcca gggatgatgg cagcattagg
      541 tgttatattt ggagaacaag catcagcact aattggtagt ccatcacttt tacttccaat
      601 agcaattgga attatagtaa tagttgcagg gcttaatatg ttaggttcaa aaactggagg
      661 agtcatacaa actgtttcta caatttgtaa gttaatacca cttattttaa taatggttgt
      721 tggatttatt aaaggtggtg gaaataatcc aatacttaca cctatggttg gtgaaggatt
      781 aagcctgggt agtgtactag gtcaagtttt aattgctata ttatttgctt ttgatggatg
      841 gatgaatgtt ggtactttag ctggagaaat gaagaatcct ggaaaagacc ttccaaaagc
      901 tataataggt gggttgtcag ttgttatggc tgtttatttt ataataaatt tagcatatct
      961 ttgggtatta ccagctaatg aattagcaaa ttatgcttct cctgcatcag cagttgctga
     1021 agttatattt ggttcaatgg gtggaaaaat aatatctgta ggtatattaa tttcagtgtt
     1081 tggagcatta aatggatttt tactaactgg ttcaagggtg gcatatactt tagctacaga
     1141 taagacttta ccaaagtatg gtatattttc taaattaaat tctgctcaag ttccagcaaa
     1201 tgcaatagca ttagtatctg ttattgcatc tatatatgct ttgtcaggtc aatttaattt
     1261 attaactgac ttagctgtat ttgctacttg gatattctat gtattaactt ttataggggt
     1321 tatgaaactt agaaagactc atccaaatat accaagagag tataaagttc cattatatcc
     1381 tattgttcct ataatagcta tagcaagtgg tatatttgtt gtagttaatc aattgtgttt
     1441 tgcaggtatg aaaactacta tgatatctat aggaggtctt gtaataacag ctataggctt
     1501 accagtgtat gcttatatga ctagaggagt aaaaagataa accaagtagt ttacaaatgc
     1561 ttcataatta aaataaaaga gactgtctca aatagagata agtctctttt ttattgttaa
     1621 aatggtaaag atatgtttga ttttacaaaa aaagagcgtt ccatgaacta aaaagtttat
     1681 tttaaggtat tcattttatt tttagttttt tgattataaa attaaacatc taaaaaatta
     1741 tttattttaa aatactttat tttaaagtgt tttttatcaa actaagtggt atctgtacaa
     1801 caaatattat acatagcttt tatgaaaatt aaatctttct gttatatata atagaatatt
     1861 gtattatata gaaaatatta cctgattaat atagtgattt ataaatgaga ttagaaaatt
     1921 ttatttgata acaaaaatta gatagtatga atatataatg tatgtattaa aaatgtggca
     1981 aatagttgtt ttgctattta ttatttgttt aatatttcta atttataaaa aaaaaattat
     2041 aaattttaaa aattataaat gacattttaa ctagaattaa ttgtaaaaaa cactatataa
     2101 tactcaattt tcaacattct atacaattat acagaaatta tacagcataa taatcaccga
     2161 aataacaaat tttaaaaatt aagcaaaact ttttgtcgaa gttcaacgtc tatatatatg
     2221 tagtgtaaat ttttgggata aaatactaca aaaatataaa tgtaaaaata tagtaatatt
     2281 ggaggtcgaa cgatgagaaa taaaaagaaa aaaataaata gaaagaagtt gtatttgctt
     2341 ttaagtgcta ttgtagtgtg tctggctttt atagtagttg gtgttcgcgt cagctcttta
     2401 aatatgaagg aaaatgaaat tagtagaaat gcaaaactgt caagttctac tattacagat
     2461 atagtatcta atacatcaat agaagttagt aaagggccaa gtaaaagttc tggaaaaata
     2521 gcatacataa ctatagatga tggtccatct aaatttactg acgagatgat aaaaacttta
     2581 aataaataca atgttaaagc aacttttttt atgatagatg ggaatatgaa ggaatatcca
     2641 cagcaagtta aaaatataat taaaaatggg aacacagcag gttttcatag tgtatcacat
     2701 gatattcaca agctttatgt tactagtaca tcagcaaaag aggaatttga tacaaatgat
     2761 caaacttttt ataagataac tggtaaacat tcaaaagtaa taagaatacc ttatggaagc
     2821 aaaccatata caccacaagc ctcttatcag gctttagttg atgctggata taaaatttgg
     2881 gactgggact tagatacaga agactggaga tctaattctt ctcaaattgt acaaaatgta
     2941 aaaaatcata ttaagaatag aaaaggtgaa gataaagacc aacttgtagt tttaatgcat
     3001 gagaaaaaac agagtgcaga agctttagat tcagttttaa aattcttatc agatgaaggt
     3061 tatgaatttg cgccagtaga tcaaaaccaa ataccaaaaa attattggtt acgtaattta
     3121 gagtagttaa aatataagaa tattgattga tatttttaga aattgagaat aaaaatgagt
     3181 gaggtgtagg tatattgaat aaaaaacttt atataggaat ggtcggaata ttgtctttga
     3241 tgatggttgg ttgtaataaa agtttagcaa aagtaaatga tgtggaaatc acaaaagaac
     3301 agtacaaaaa aacaaaagca gttttatctg ctactaataa ttatataaat gggcagtctt
     3361 tagatgaatt agaaaaaact ttggataaaa aaggtagaaa taaattagaa aatgttataa
     3421 tatcgtttat ggtggataat gaacttttat atcaagaggc taaggataaa ggactaactc
     3481 caagtaaaag tgaagtagac tcaaaatatc aagaactaga agataagatg aatttgaata
     3541 caagctataa ggaaaaaatg gacaaagcag gtgttgataa agattattta aaacaagaaa
     3601 tatctagaga tttagcaata gataaaaata aaaaggcctt tgaagataga ataaacataa
     3661 gtgataatga tatggaagcc tactatacaa gtcataaaaa agattttaat gtagaagaag
     3721 taagtgcttc tcagatactt atatcgactt tagataaaaa taaaaaagaa gtaagcaaag
     3781 ataaaaaaga agctttgaag aagaaggcag ataatatatt gactaaaatc aaaaatggag
     3841 aaagttttga aagtttggct aaaaaatatt cggatgataa agcaactgga aaaaatggag
     3901 gacagctagg atattttaca aaggatgata aaaatgctga gtttacaaag gaagtgttca
     3961 aattaaagaa aaatgaagtt tcaaatgtgt ttgaaactag ttatggatat catatagtca
     4021 aagttactga taaaagagaa agacaaaaaa gttttaatga gtgtcagagt ttaataagag
     4081 aatctatttt aaatgaaaag tatattgagc atataaaaaa actgaatgaa gatgctaaaa
     4141 tagacagata gaatttctaa cagctcaatc ctagcctgta atcggaggga gattttacag
     4201 gaatgtttaa gagtttaaag agaacgaaag ttgagaaata cattatcgat aataaagact
     4261 ctttttatag aatagcatat agttatacga agaatgaaga agatgcctta gatgtggttc
     4321 aagaagccat gtataaggca ctatactcag tggaaaatat taaagaagta aattatataa
     4381 agacatggtt ttataaaatt ttagttagaa cgagtataga ttttattaga aaaaaccgta
     4441 aatataataa tatgacagat attgacctta tagatgagac tggagagtat gataaatata
     4501 ctgatttgga tttaagaaga gctttggaag aattacctat tgaatacaaa tctattataa
     4561 tattaagatt ttttgaagat ttaaagattg aagaagtagc aataatattg gatgaaaatg
     4621 tgaatactgt taaaactagg ttatatactg ctttaaaaaa actaaaatta aaaattgaag
     4681 agtagggata aaaagaatga caagcaaaga aaggttaaat aagttaaaag atgagtatca
     4741 taaaattcca atacccaaga aattagatac tataataaat catgaaaaaa tagaaaacat
     4801 atatcgagag aaaaataaaa aagtaaatag attaagattt aaagttgcaa tagcctttgc
     4861 atgtatattt acagtattag taaatataag tcctgtattt gcagacaatt tttctaagat
     4921 acctgtaatt ggagcaatag tagaagtaat aactataaaa aattatagtt taaaaagtga
     4981 aaattatgaa gctgagattg atattcctaa aatacgaggt ttaaaagata aaaacttaga
     5041 acaaagatta aacagtagtt ttatggaaga tggaaaaagg ctttatcatc aattccaaga
     5101 gagaatggag aagatacaat catcaaagaa taaaggatat aaatctttaa gtttgagtta
     5161 tagtgtaaaa aataattcta aaaaatttct atcaatagag atgacaaaaa atgagataga
     5221 ggcttcatca tatgtgagta aggtacatta tactattgat aaaaaaagac aaatagtttt
     5281 gactttgcca atgcttttta aagatgataa gtatataaaa gttataagtg ataatataaa
     5341 agaacaaatg agagaacaaa tgaaaaagga tagtacaaaa tcctatttta tagatcaaaa
     5401 aaaagatttg cctgttgaag attttaaaac aattaataag tatcaggatt tttattttaa
     5461 taaaaatgaa gaccttgtaa tttgttttga tgaatatgaa gtagcacctg gttatatggg
     5521 tgcagttgag tttgtaatac catataaagt aataaaagat ttgtaaattg aatagtagtt
     5581 tatatataaa tattttaaga aggacaatat gactacatat aaaaagctta aaaaatctat
     5641 atttaaaatt gctatatttt caatatgctt attagtttca ttagtagata caaaccctat
     5701 atttgcaggt agttccttta atgaaacttc aaatagtgat acgataaagg tgttaaatac
     5761 taagagtatc aactttaaac aagacaatta tgaagtgaat gtgagtattc ctaaaataaa
     5821 aggtttaaaa gataaaactt tagagaataa attaaacaat gagtttttgc aagatgggaa
     5881 aaaaatttac agtgaatttc aaaataaaat gaaaaaggaa gataataagg gtcatagata
     5941 cctaaatgta atccacaatg tcaaaaataa ttctaaggac tttttatcaa tagaaatgac
     6001 aaaagaagag atagaagctt cctcatctat aactaagaag cattacactg ttgataaaaa
     6061 tagaggaata ctattaaatt taccaatatt ttttaaagat agtagatata ttagagctat
     6121 aagtgataat ataaaagagc agatgagaaa tcaaattaag aaagatgata caaaatctta
     6181 ttttatagac caagataaag actcgccagt gaaagatttt gaatctataa ataagtatca
     6241 agatttttat tttaataaaa atggaaatct tgtgattagt tttgatgaat atgaagtagc
     6301 acctggttat atgggagcag tagaatttgt gataccaaat aaagtaataa aaagactaag
     6361 atagatatat agaagatttt tagatagact ggtaaggaga attatatgaa tatatatgaa
     6421 caagcaataa gattaataga aaataatgag gatttcgcat ttgctacaat aacgtctcat
     6481 tcaggttcaa caccacgtga aactggagca atgatgattg tgaaaaatga ttctactata
     6541 tttggctcag taggaggagg tagtgtagaa gcagaatgta taaaacatgc aattaatgtt
     6601 ataaaaaaca gagaatcaat gttgtataaa tttactctaa acaaatctga tgtggcaaaa
     6661 ctaggaatga tatgtggagg tactggagaa atacaaatag attttataga tagtaaatta
     6721 aaaagtaata tagaaaaatt taataagaga ctaaaggaaa atacaagtaa agcatatata
     6781 tttggtgcag gtcatatttc aagagatgtt gctgtgatac tatctctttt agaatttaga
     6841 acagtagtaa tagatgatag agaagaattt gctaatcatg aaaggtttcc agaatcagaa
     6901 gtagtagttt tagattcttt tgaaaacata ccagattttc caactgacaa aaatagttat
     6961 ataattattt taacaagagg tcatctatat gattcaagtg ctttagaatg ggctcttaaa
     7021 agagaggctg gttatatagg tatgattgga agtagaacaa aaattggatt gacttacgaa
     7081 aaactcatga aaaaaggttt taagaaggaa gaattatcaa aagtacatgc accaataggc
     7141 ataaaattga atgctcaaac accagctgaa atagctgtat gtatagctgc tgaacttata
     7201 aattgtagag ctaataagga aaaataaact aatgaacaca gggagtaaag atattgatac
     7261 tttaaaggtt aattttagag ggattgaaat aaaagcagtt ttagtatata aaaatagaaa
     7321 aaatatttct ataaaaatag atccatttgg caaaataact gtaatgagtc ctcctaaaat
     7381 atccaaaaaa ataataaaag atataattat tgaaaaagga gactggatac ttaaaaagtc
     7441 agaaaaatgt aaaggaagag aggaagtata taaacaaaga atgtttataa ctggcgaaaa
     7501 atttctttat ttaggtgaag agtaccattt agttataaaa gaactgttga gagattctgt
     7561 caaaaaaagt aactgtagaa taactattaa cgaatatcaa atagttgttc agacaaatga
     7621 tacaagtaca gattttatta aaaaatcttt aaaatcttgg tataagatgg aaagtgaaag
     7681 aatagtatta gagagaatag attttcttaa attaaattgt gaaataatga agcaattagt
     7741 tccagcgagt gttaaggtaa aagaacaaaa taagagatgg ggaagttgta cagctcaaaa
     7801 aaatatttat ataaactcaa aaatatctat ggcaagatta gatgtaattg attatgtaat
     7861 aatacatgag tttagccatt tagtacatat gaatcactct aaaaaattct atgatttagt
     7921 aaaatccatt atgcccgatt ataaagataa agaaaattgg ctaaaaataa atggatataa
     7981 aataataatc tgaaaacgat tattccaaaa tataggcgta aagtataaaa gaagtattat
     8041 tgtgaaaaaa ataaataatc tgaaaatttt aaaaaaagtc attgacattg taaatgatag
     8101 ggaatataat ctatattaac aacaaaacag aattaaaata taaaattaaa aaattaaaag
     8161 caatgacaga gacaacaata ctaatagtgt tatccacaga gaaccaatgt tgctgagaat
     8221 tggtgttaac agtagtataa tgatcactct ggagcttttg tactgaatat ttttagtaag
     8281 tacaaacgta tgtcagcgtt acatgactaa ggttaaggta attaattacc cgacctgaaa
     8341 aaagaggggt agatgtattt tttatatcta caaataaggt ggtaccgcgg aatataactt
     8401 tcgtccttat aagtaatatt tatattgctt ataaagatga aagttttttt attttaagcg
     8461 atataaataa atttaatcca tataaaatta ataaaaaaat aataaaaata aggagggatt
     8521 tttatggaaa atactgtata tgctaaatta aaccaaggaa tagattcttt tttaagagtg
     8581 gctatgactc taagaagaag agaggttgat atacaatcaa taagtatgac tgtagataat
     8641 atgaataatt caggtataaa attaatagta aatgaagaaa agacatcctt agattctgtc
     8701 ttaaaccata tgaaaaaact acatgatata agagagataa ctgttgaaag aatgagacat
     8761 taattaaata tattttataa agctaaagat aaatatgctt attttaaaat aaaaaactaa
     8821 agataaatat taaataagaa aaatcttaga tta
//
LOCUS       DAMKNB010000118         8804 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.124, whole genome shotgun sequence.
ACCESSION   DAMKNB010000118 DAMKNB010000000
VERSION     DAMKNB010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8804)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8804)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8804
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.124"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            354..1370
                     /gene="gap"
                     /locus_tag="PC494_003304"
     CDS             354..1370
                     /gene="gap"
                     /locus_tag="PC494_003304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011948756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HDF3913775.1"
                     /translation="MKIKVGMNGFGRIGRAVLRIAQEELGDNIEIVAINARATTESLA
                     HLFTYDSCYGTFRGEVEAKDEDTLVVNSKEIKILRYNDPEELPWKELGVDIVIESTGL
                     FTQREKAEKHIKAGAKKVIITAPGKNEDITIVIGVNEKEYDNEKHNIISNASCTTNCL
                     APFAKVLDEKFGIVKGLMTTVHSYTNDQRILDKSHKDLRRARAAAESIIPTTTGAAKA
                     VSRVLPQLEGKLNGFSLRVPTPTVSLVDLVCELKENVTSEQVNSVLKDAAEGELKGVL
                     GYCDKPLVSIDYKGDSRSSIIDALSTMVIEDNMVKVVSWYDNEWGYSSRTVDLVKYVA
                     EKLK"
     gene            1765..2934
                     /locus_tag="PC494_003305"
     CDS             1765..2934
                     /locus_tag="PC494_003305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3913776.1"
                     /translation="MEKLTDRRQVKAVSMETFIFLILLVVGFGYVGSIMGAGMMFKVI
                     MSTAHALLLETVFLIMAMAVLAGALSALLSEFGVIALINKIFAVFMKPLYGLPGASIA
                     GAITTYLSDNPAIIPFAKDKTFTQYFKQYQVPALCNLGTAFGMGLILTTFMISQGTEY
                     VLPALIGNLGAIIGSVISVRIMLTFTKKFYKYNPEEDKATGTLEKKDEFREIREGNVF
                     QRALDAILEGGKMGVDMGMAIIPGVLVVCTLVMLLTFGPSTDPVTGQEVYTGAAYEGI
                     KLLPVIGDKLGFILEPLFGFTSPEAIAFPITSLGAVGAAMSLVPEFIKSGAITPNDIA
                     VFTAMGMCWSGYLSTHIGMMDALNARQLAGKAILSHTIGGLCAGAAAHFIFTLVG"
     gene            3314..7567
                     /locus_tag="PC494_003306"
     CDS             3314..7567
                     /locus_tag="PC494_003306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxyacyl-CoA dehydratase"
                     /protein_id="HDF3913777.1"
                     /translation="MDELFHIGIDVGSTTVKVVVLNNSNNIVHKEYRRHYSDVKKSVK
                     EVLNGIYEKLGDINTTIIITGSGGIGISKKLGVKFVQEVISSTKSIEYFHPETDVVIE
                     LGGEDAKITYLSGGIDQRMNGICAGGTGAFIDQMASLLKTDASGLNELAKGYNVIYPI
                     ASRCGVFAKTDIQPLINDGANQTDIAMSIFNAVVVQTVSVLSCGRKIEGNVAFLGGPL
                     YFLSELREAFKRVLDLKDENIIFPENAQLYIAIGAGLLSVDEDNIQLKSLIEKLDSIK
                     NIEDGEVNLLEPLFKDKNEYEEFSRRHEKEKINYVDINSIKSNCYLGIDAGSTTTKAA
                     LIDEDGRLVYSYYNSNEGNPLKTTIKVINEVYDILPKNIKILSSTVTGYGEGLIKKAL
                     KIDNGEIETIAHYKAAKFFNKDVDFILDIGGQDMKCLKIKDGVIDNIILNEACSSGCG
                     SFLETFASSLSMTIEEFAHEGIYSQNPVDLGSRCTVFMNSRVKQAQKEGASVGDISAG
                     LSYSVIKNALFKVIKIRDLNEIGNNIVVQGGTFYNDLVLRSFEKLIGKNVIRPNISGI
                     MGAFGSALIAKEKYESGYKTSLLSKEELNNIKLEASVTRCKGCSNHCLLTINKFSDNE
                     IFISGNRCEKGEAIYGDKKIGLEKKKPINLFKYKYNRIFRYKPLEKEEAKNGEIGIPR
                     VLNMYEDYPFWFTFFNAMGFRVVLSDRSSKQLYETGITSIASETVCYPGKLVHGHIEN
                     LIAKGIKNIFYPSVTNENKEDSNADNYYNCPVVISYSEVIKNNVENIRNKNINYINPF
                     ISLNDKEKLKKRLYDELSRHFSDIKITKEEVNHAVDKATDEQNLFKMEIQAAGERALK
                     EIKERNMKGIVLCGRPYHIDPEINHGMPELINSLDMAVLTEDSICHLANVQRPLRVVD
                     QWVYHSRLYKAASFVRDKNYLELVQLNSFGCGLDAVTTDQVQEILNEKSKIYTIIKID
                     EGNNLGAAKIRMRSLKAAMFERESKNIDVKNIKVNRIQYAKNNQITNKHTILAPQMSP
                     IHFQFLEKAVNLSGYNIEILKDTDSSVIEEGLRYVNNDACYPAIIVVGQLITALKSGK
                     YDLNNTSVTITQTGGGCRATNYIGFLRKAIYDAGFKDIPVIALSVNGIEDSGIMDNIS
                     LKLINRLFMSVVYGDLLMKVLYRVRPYEKVTGSANALYEKWVDICKSSLVKAKISVFT
                     RNIKDIVKEFDNLEILDIKKPKVGLVGEILVKFHPIANNNLVDILEREGAEAVVPDLT
                     NFFLSCAFNTIYKHTHLEGSRKSRMIGEAFIYITGIYQRVYKKALDKSERFYAPANIK
                     NVAKSTEPVVSLGNQTGEGWLLTGEMVELLNEGVENIICMQPFGCLPNHIIGKGSIKE
                     LKRLYKNANIIPIDYDPSASEVNQLNRIKLMLSKAFKNI"
     gene            7716..8210
                     /locus_tag="PC494_003307"
     CDS             7716..8210
                     /locus_tag="PC494_003307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HDF3913778.1"
                     /translation="MSLVYDVYKSKLGNLYILSEDGFIVSIYIGDEKFNNLKNECIKK
                     GIDIKRSKEDLKEAISQIDDYFNGKRKVFNLNIRIEGTEFQKSVYREMLKIPYGETLC
                     YSDIARNINNPKSVRAIGQASKSNKIPIIIPCHRVVGKKDIGGYMGNHSDLKEILLNL
                     ERQS"
     gene            8326..8703
                     /locus_tag="PC494_003308"
     CDS             8326..8703
                     /locus_tag="PC494_003308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="monooxygenase"
                     /protein_id="HDF3913779.1"
                     /translation="MCDKVIASKYHEKGFNCAESVIKAYNEEFNTDIPVCLGSGLGSG
                     CGVASLCGAVNASNIIIGYVKGRNHEDESTKAKVYAKDLTTTVRKEYGSELCIDLKKD
                     LVACREIMDFAYDSLKETLKKEL"
BASE COUNT         3568 a          915 c         1600 g         2721 t
ORIGIN      
        1 aaaaaatcat atattttttg aactaaataa aaatttattt ttattatttt aaattagagg
       61 agattcttga agatatatta tttttaaaaa taagtatagt ttaaaaattc aaaaaaaaga
      121 tggcaaaata tgtcccaagg gacattgagt aaaataaatg atttcagctt atttacacta
      181 aaaagtacat actaaatgag gggtaaaata aagaaaaatg atatactaat tgtcttttga
      241 taataaaaaa acatggaatt tgattattta atcaagaaaa agtattgaac aaatgattta
      301 tttagtgtac aataatcatg taaaaacata gtaatggagg gagacatttc ataatgaaaa
      361 ttaaggtagg aatgaacgga tttggaagaa taggaagagc tgtattaaga atagctcaag
      421 aagaattagg agataatata gaaattgtag ccataaatgc aagagcaaca acagaatctt
      481 tggcacattt atttacatat gattcatgct atggaacttt tagaggtgaa gtagaggcaa
      541 aggatgaaga cactctagta gtaaactcta aagagataaa aatattaaga tataatgacc
      601 cagaagaatt accttggaaa gaattggggg ttgatatagt aatagaatca acaggattat
      661 ttacacaaag agaaaaggca gaaaaacata ttaaagcagg agcaaaaaaa gtaattataa
      721 cagctccagg aaaaaatgaa gatataacta tagttatcgg agttaatgag aaagaatatg
      781 ataatgaaaa gcacaatata atttcaaatg catcttgtac tacaaattgt ctagctcctt
      841 ttgctaaagt attggacgaa aaatttggta tagtaaaagg gttaatgact acagtacatt
      901 catatactaa cgatcaaaga atattagata aaagccataa agatttgaga agagcaagag
      961 cagcggctga atctataata cctaccacta caggagcagc aaaagctgtg tcaagagtac
     1021 taccacaatt agaaggaaaa ttaaatggtt tttcacttag agtaccaaca ccaacagttt
     1081 cacttgttga tttagtgtgc gaacttaaag aaaacgttac atctgagcaa gttaactctg
     1141 tgttaaaaga tgctgctgaa ggagaattaa aaggtgtttt aggatattgt gacaagccac
     1201 ttgtttctat agattataaa ggagattcaa gatcatctat tatagacgct ctatccacaa
     1261 tggttataga agacaatatg gttaaggtag tttcttggta tgataatgaa tggggatatt
     1321 cttcaagaac tgttgactta gtaaaatatg tagctgaaaa attaaaataa tatatatttc
     1381 ttaaagcaaa ttttaaaaaa attttttaaa aaaattatat aaaactaaaa aaaaagatta
     1441 tgaaaaatat tgaaggaaaa attttttcat aatctttttt ctttcatgca aaaagataca
     1501 agttacaact tatatttgca tattaggtcg ttagagaagt atatatatat ttagtaagga
     1561 atcatacttt ttataaaatg aaagataaga tgtcgaaaac ttgcataaat ctgaaaaatt
     1621 tttattatta aaatactgat ttccatttta aaaatgataa aaaaatgaca aataaagttg
     1681 caaatagtaa tacttataag tataattaaa aaagagaaaa ggttttgtta aactttataa
     1741 caaaaaaaga agggatgatt caaaatggag aagttaacag acaggagaca ggttaaggca
     1801 gtaagcatgg aaaccttcat tttcctaata ttactagtag ttggttttgg gtatgttggt
     1861 agtattatgg gagcaggaat gatgttcaaa gtaataatga gtacagcaca tgctttacta
     1921 ttggagacag ttttcttaat tatggctatg gcagttcttg caggcgcatt aagcgcacta
     1981 ctttcagagt ttggagtaat agcgttaatt aataaaattt tcgctgtatt tatgaagcct
     2041 ttatatggac tacctggtgc tagtatagca ggagctataa caacttattt atcagataat
     2101 ccagctatta taccttttgc taaagataaa acattcacac agtattttaa acaataccaa
     2161 gttccagcat tatgtaactt aggaacagcc tttggtatgg gacttatctt aacaacattt
     2221 atgatttctc aaggtacaga atatgtactt ccagcattaa ttggtaattt aggtgcaatt
     2281 ataggtagtg tcataagtgt tagaataatg ttgacattta ctaagaagtt ttataaatac
     2341 aatccggaag aagataaagc aacaggaaca ttagagaaaa aggatgaatt tagagaaatc
     2401 agagaaggaa atgtatttca aagagcttta gatgcaattc ttgaaggtgg taaaatgggg
     2461 gtagatatgg gaatggctat aattcctgga gtcctagtag tatgtacatt ggtgatgtta
     2521 ttaacttttg gaccatctac agatcctgtt acaggtcaag aagtttatac aggagctgca
     2581 tatgaaggaa taaaattact tccagttatt ggagataaac ttggatttat attagaacca
     2641 ttatttggat ttacatcacc agaggcaata gcattcccta taacttcatt gggagctgtt
     2701 ggcgcagcaa tgtctctagt tccagagttt ataaagtcag gagctataac tcctaatgat
     2761 atagcagtat ttacagctat gggtatgtgt tggagtggat atttaagtac acatattggt
     2821 atgatggatg cattaaatgc tagacagttg gcaggtaaag ctattctttc tcatacaata
     2881 ggtggtttat gtgcaggagc agctgctcac tttatattta cactcgtagg ataaatgtaa
     2941 tcagctaaga taaaaaataa tatacaaaaa atggttgttg atatgtaata agaatttaca
     3001 tatcaacaac catttttttc tgactaaaga taatttataa tacataaaca ttaagtggat
     3061 attagagtta agttatattt atgtaaaaag taacaaaaat ctgtagaaat ttatgacaaa
     3121 atttagtaca ctaactatat gttcttattt aaaatttaag gttagaatta ggaattacct
     3181 agtagagtaa gctttgatta ataaaagaat cataaaataa aaatattagt cataaagatt
     3241 ataaataact tacttaaaat aaagccatag aacttacaaa aattaaaaaa gcatataaat
     3301 atggaggggt acaatggatg aattatttca tataggaatt gatgtaggtt ctacaacggt
     3361 gaaggttgtg gtacttaata atagtaataa tatagttcat aaagaatata gaagacatta
     3421 ttctgatgta aaaaaatcag ttaaagaagt actaaatggt atatatgaaa aattgggaga
     3481 tataaatact accattataa taactggttc aggtggaatt ggaatatcaa aaaaattagg
     3541 tgtaaaattt gttcaggaag ttatatctag tacaaaatca atagagtatt ttcatcctga
     3601 aactgatgtt gtcatagaac ttgggggtga agatgcaaag ataacatatc taagtggagg
     3661 aatagaccaa agaatgaatg gaatatgtgc aggtggcact ggagcattca tagaccagat
     3721 ggcatcactt ttaaagacag atgccagtgg attaaatgaa cttgctaaag ggtataatgt
     3781 tatatatccc atagcttcaa gatgtggtgt ttttgctaaa acagatattc aacctcttat
     3841 aaatgatgga gccaatcaga ctgatatagc aatgagtatt ttcaatgcag ttgtcgtaca
     3901 aactgtgagt gtcctttctt gtggaagaaa aatagaagga aatgttgcgt ttttgggtgg
     3961 tccattgtac tttttatctg aacttagaga agcatttaaa agagtattag atttaaaaga
     4021 tgaaaacata atcttcccag aaaatgcaca actttatatt gctattggag caggattatt
     4081 atcagtagat gaagataata tacaactaaa atctctaata gaaaaattgg atagtataaa
     4141 gaatattgaa gatggagaag taaatttatt agaaccttta tttaaagata aaaatgagta
     4201 tgaagaattt tcaagaagac atgaaaaaga aaaaataaat tatgtggaca taaattcaat
     4261 aaaaagcaat tgttatttag gaattgatgc aggctcaact acaactaaag cagcacttat
     4321 tgatgaggat ggaagacttg tatattctta ttataatagc aatgaaggaa atccattaaa
     4381 aacaaccatt aaagttataa atgaagtata tgatatatta ccaaaaaata ttaaaatatt
     4441 gagttcaact gtaactggat atggagaagg tcttattaaa aaagctctta aaatcgataa
     4501 tggagagata gagactatag cacattacaa agctgctaaa tttttcaaca aagatgtaga
     4561 ttttatactt gatattggtg gtcaagatat gaagtgccta aaaataaaag atggagtaat
     4621 tgataatata atattaaatg aggcttgttc atcaggttgt ggctcatttt tagagacatt
     4681 tgcaagttct ttatctatga caatagaaga atttgcgcat gaaggtattt attctcaaaa
     4741 tcctgtagat ttaggttcaa gatgtactgt atttatgaat tctagagtaa aacaagctca
     4801 aaaagaaggt gcaagtgttg gagatatatc agcagggcta tcttattcag taataaaaaa
     4861 tgctttattt aaagtaataa agattagaga tttaaatgag attggtaata atattgttgt
     4921 acaaggtgga accttttata atgatttggt gcttagaagc tttgaaaaac taattggaaa
     4981 aaatgtaatt agacctaata tttcaggaat tatgggagct tttggttcag cacttatagc
     5041 taaagaaaaa tatgaaagtg gatacaaaac atccttgtta tctaaggaag agttgaataa
     5101 tatcaagcta gaagcaagtg taactagatg taaaggttgt tcaaatcatt gtcttcttac
     5161 aataaataaa ttttctgata atgaaatttt tatttcaggt aatagatgtg agaaaggtga
     5221 agctatttat ggtgataaaa aaataggatt agaaaagaaa aaaccaataa atttatttaa
     5281 gtacaaatac aatagaattt ttagatacaa accattggaa aaagaagaag caaaaaatgg
     5341 ggaaataggg ataccaagag tattaaatat gtatgaagat tatccatttt ggtttacttt
     5401 tttcaatgct atgggcttta gagttgtact ttcagatagg tcatcaaaac agttatatga
     5461 aactggtata actagtattg catctgaaac agtttgttat ccaggaaaat tagttcatgg
     5521 acatatagaa aatttaattg caaaaggtat aaaaaatata ttttatccaa gtgtaacaaa
     5581 tgaaaataaa gaggattcaa atgcagataa ttattataat tgtcctgttg taatatcata
     5641 ttctgaagta ataaaaaaca atgtagagaa tataagaaat aagaacataa attatataaa
     5701 tccatttata agtctaaatg acaaggaaaa attgaagaaa agactctatg atgaattatc
     5761 aagacatttt tctgatataa aaataactaa agaagaagtt aatcatgcag ttgataaagc
     5821 tactgatgaa cagaatttat ttaaaatgga gatacaagca gcaggtgaaa gagcacttaa
     5881 agaaataaaa gaaagaaata tgaaggggat tgtgttatgt ggaagaccat atcatataga
     5941 cccagaaata aatcatggaa tgccagagct tataaattca ttagatatgg cagtgcttac
     6001 tgaagactct atatgtcatt tagccaatgt acaaagacca cttagagttg tagaccaatg
     6061 ggtatatcat tcaagattgt ataaagcagc tagttttgta agagataaaa actatttgga
     6121 acttgttcaa cttaattcat ttggctgtgg attagatgca gtaactacag accaggttca
     6181 agaaatactt aatgaaaaat cgaagatata tactattata aagattgacg aaggcaacaa
     6241 tttaggagca gctaagataa ggatgaggtc cttaaaagca gctatgtttg agagagaaag
     6301 caaaaatata gatgtaaaaa atataaaggt aaacaggata cagtatgcta aaaataatca
     6361 gataacgaac aaacatacta tattagcacc acaaatgtct ccaatacatt tccaattcct
     6421 tgaaaaagct gttaacttaa gtggttataa tatagaaatt ctaaaagata ctgatagtag
     6481 tgtaattgaa gaagggttaa gatatgtaaa taatgatgca tgttatccag ctataatagt
     6541 tgtaggtcag ctaataacag cattaaaatc tggcaaatat gatttaaata acacttctgt
     6601 tactataact cagactggtg gaggttgtag agctacaaat tatattggat tcttaagaaa
     6661 ggctatatac gatgctggat ttaaagatat tcctgtcatt gcacttagtg taaatggaat
     6721 agaagatagt ggtataatgg ataatatatc actaaaatta atcaatagac tctttatgtc
     6781 tgttgtttat ggtgatttgc tgatgaaagt actatataga gtaagaccat atgaaaaagt
     6841 tactggaagt gcaaatgctc tatatgaaaa atgggttgat atatgcaaat cttctcttgt
     6901 taaagcaaaa atttctgtat ttactagaaa tataaaagat atagtaaaag aatttgataa
     6961 tttagagata ctagatatca aaaaaccaaa agtaggtttg gttggagaaa tattggtgaa
     7021 attccatcca attgcaaata ataatttagt agatatatta gagcgagaag gtgctgaagc
     7081 agtcgtgcca gaccttacaa atttcttctt aagttgtgcc tttaatacta tatacaaaca
     7141 cactcattta gaaggaagta gaaagagtag aatgatagga gaagcattta tatacataac
     7201 tggaatatat caaagagtat ataaaaaagc acttgataag agtgagagat tttatgctcc
     7261 agccaatata aaaaatgttg ctaaaagtac agaaccagta gtgtcattag gtaatcaaac
     7321 tggagaaggt tggcttttaa caggtgagat ggttgaatta ttaaatgaag gtgtagaaaa
     7381 cattatttgt atgcaacctt ttggatgttt acctaatcac ataattggta agggttctat
     7441 aaaagaatta aagaggttgt ataaaaatgc aaatataata cctattgatt atgacccttc
     7501 tgcaagtgag gtaaatcaac ttaacaggat aaaacttatg ctttctaagg cttttaaaaa
     7561 tatataagat ttatattttg atatgttaaa agttaatgaa tttaaaaata tactctatat
     7621 taagtatcta taaaaaagag ttatcctatt ttttagggta actctttatt agttaaaaaa
     7681 ttatatgtat actgatatta aaggggggaa gtaatatgag tttagtatat gatgtttata
     7741 aatcaaaatt aggaaatttg tacatattaa gtgaagatgg ttttatagtt agtatataca
     7801 taggagatga aaaatttaat aatttaaaaa atgaatgtat taaaaaagga attgatataa
     7861 agagaagtaa ggaagattta aaggaagcaa taagccagat agatgattac tttaatggaa
     7921 aaagaaaagt ctttaattta aatattcgta ttgaagggac tgaatttcaa aaatcagttt
     7981 atagggaaat gttaaaaata ccttatggag aaacattgtg ttattcagat atagcaagaa
     8041 atataaacaa tccaaaatca gtaagagcaa taggacaagc aagtaaaagt aataaaattc
     8101 caataataat accttgtcat agagtagttg gcaaaaaaga tattggtgga tatatgggga
     8161 atcattctga tttgaaagag atactattaa atttagaaag acagagttaa cttagaaaga
     8221 aatgttttta ttgttaatat ttgatataat aatagtaaaa agaagtattt tttacaaaaa
     8281 caatgaagaa tttattttaa tttataaaaa tgagggggaa ttttaatgtg tgataaagtt
     8341 atagcatcaa aatatcatga gaagggattt aattgtgcag aatcagttat aaaagcatat
     8401 aatgaggaat ttaatacaga tataccagtt tgtttaggaa gtggactggg ttcagggtgt
     8461 ggggttgcta gtttatgtgg tgcagtaaat gcatcaaata taataattgg atatgtaaaa
     8521 ggcagaaacc acgaagatga aagtactaaa gctaaagtat atgctaaaga tttaactaca
     8581 acagtaagaa aagagtatgg ttcagagtta tgtatagacc taaaaaaaga tttagttgct
     8641 tgtagagaaa taatggattt cgcatatgat agtctaaagg aaactttaaa aaaagaatta
     8701 taagaaaata agctatcaag tataaattat ttgatagctt atttttatag tcgatactaa
     8761 ataaatcaaa tatattttag aattattatt tgtaaataaa cagc
//
LOCUS       DAMKNB010000119         8716 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.125, whole genome shotgun sequence.
ACCESSION   DAMKNB010000119 DAMKNB010000000
VERSION     DAMKNB010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8716)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8716)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8716
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.125"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            100..558
                     /locus_tag="PC494_003309"
     CDS             100..558
                     /locus_tag="PC494_003309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HDF3913780.1"
                     /translation="MANTMDLLKDKLKETGFKITPQRRAIVEILLKHDHSHLSSEEIY
                     DLVRVDCPEIGLATVYRTMQLLDEIGLISKLNLDDGCIRYEISLHKEDCHNHHHLICK
                     NCGKIMEAKEDLLDNIEKEIQSLYKFKILDHDVKFYGLCDECNGVSDSEE"
     gene            complement(675..1412)
                     /locus_tag="PC494_003310"
     CDS             complement(675..1412)
                     /locus_tag="PC494_003310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HDF3913781.1"
                     /translation="MRGKTHCAIGILTAIQTSLIFKIPISLVDILVSATFAVLPDLDK
                     SNSMVSNFILKNNVSKYIYRIFIYAVNIIIFFISININDNFYLSAIITFVAIIIIEAK
                     LTHTFLRKVFLSLIFILLAICLYIIEVEIYFTIFCLMLSIFPWLKHRSFSHSIFATII
                     VYFLLKQIELITNINNLSFYGTIGYASHMFLGDLFTKQGIPIFYPLSEKKISLGFLTV
                     GGPFSNFIEKSFIFVLIGLIIFSILKL"
     gene            1629..3305
                     /locus_tag="PC494_003311"
     CDS             1629..3305
                     /locus_tag="PC494_003311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HDF3913782.1"
                     /translation="MQLFKKNTNKIKVMALGGLNEVGKNMTVVEYKDEIIVIDAGLSF
                     PEDEMLGVDIVIPDITYLVKNRDKIKGIFITHGHEDHIGALPYILKKINVPVYGARLS
                     IGLIQVKLKEHKMNNVKLNVIGPRQVIKLDNMEVEFLKNNHSIPDAYSIAIHTDQGII
                     YHTGDFKIDLTPIDGDVMDMHRICELSKKGVLLMLADSTNAEKPGFTMSEKTVGVGLD
                     ELFAKGNGRRIIVATFASNIHRLQQIINTAEKFNRKVAISGRSMVNVVGVAKELGYLD
                     ISDDMLIDLNDICKYEDSELVIITTGSQGEPMSALARMAFSEHKKVEIKSGDLVIISA
                     HPIPGNEKLISRVINFLFEKGAEVVYSDIADIHVSGHACQEELKLIHALVRPKFFMPA
                     HGEYRMLKRHAEIAEQLGMDKENIFVMQTGDVLELDKNSAKVANRIQTGNILVDGLGV
                     GDVGNIVLRDRKHLSEDGLMIVVVTISKDEGKVLAGPDIISRGFVYVRESEDLMDGAK
                     DIIKNVLNECEEKNIKEWAYLKNNIKENLKEYLYQKTKRNPMILPIIMEV"
     gene            3511..3711
                     /locus_tag="PC494_003312"
     CDS             3511..3711
                     /locus_tag="PC494_003312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore protein"
                     /protein_id="HDF3913783.1"
                     /translation="MDDVSRQNAIKALKQTKMEIAGEYGMNYEDAFEIIENASNKGVL
                     EGYFKKLEKKKNLGQGISRHLE"
     gene            3765..4928
                     /locus_tag="PC494_003313"
     CDS             3765..4928
                     /locus_tag="PC494_003313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HDF3913784.1"
                     /translation="MKKLASTALAILIALTPLSFSFANNKENADANQLNISSKSAILM
                     DVGSGQILYEKDAHKKLPPASVTKVMTMLLIVEALDSGKIKLDDEVQVSETASSMGGS
                     QIFLEPGETQKVDTLLKGIAVASANDACVAMAEHLAGSVEGFVDRMNAKAKELNMNDT
                     HFANTNGLPVANHYTSAHDIALMSRELLKHEMISKYLTTWMDKVVVGKKQVTVGLANT
                     NKLIKHYQGATGVKTGFTQEAKYCLSASAKRGNTHLVAATLGAETSPERFNDASSLLN
                     YGFANYESVKLCSKGDNIATLTLDKADENKVKLVAKEDLNALIKKGSSKEFEKKIEIV
                     KNPKMPIKKGTVLGKIKICKDKKVIGEVELINTKDINKASYLQMLQRIIDNMI"
     gene            complement(5139..5561)
                     /locus_tag="PC494_003314"
     CDS             complement(5139..5561)
                     /locus_tag="PC494_003314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2000 domain-containing protein"
                     /protein_id="HDF3913785.1"
                     /translation="METKNSKCVMVIDENLPMGIISNTAAIMGITLGKHAPETVGPDV
                     IDKTGNSHLGIIDIPVPILKGNKEIIKDLRKKLYTLEFNDLTVVDFSDVAQSCNLYEE
                     FTQKIASVPEDELQYFGIAIYGNKKKVNKLTGSMPLLR"
     gene            complement(5582..6418)
                     /locus_tag="PC494_003315"
     CDS             complement(5582..6418)
                     /locus_tag="PC494_003315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HDF3913786.1"
                     /translation="MRQEERTVCFDRELKIEAYRFKGIMQKFPNHFHEHYVIGFIEKG
                     QRYLSCKNKEYTTSTGDLLLFNPFDSHTCEQIDDKVLDYRCINIKPEIMKKTVFEITG
                     KNYLPKFNQPVIFRSELVPLLQELHYIIMEEELDFKKEELFFFLIEQLIEEHTEPNLQ
                     SNLENTNIEIQAVCDYLENNYAEHIVLDELSTIAGMNKYSLLRNFTKLKGITPYRYLE
                     NIRVNKAKKLLEKGVEPIDAAIQTGFVDQSHFTNFFKNFIGLTPKQYQNIFINDDSNN
                     FK"
     gene            6716..7312
                     /locus_tag="PC494_003316"
     CDS             6716..7312
                     /locus_tag="PC494_003316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-2 protease family protein"
                     /protein_id="HDF3913787.1"
                     /translation="MLSMNIGEIVASLVGIAMAISIHEFGHAYSAHLLGDDTAKAYGR
                     MTLNPVRHVDPIGLLAMFILKIGWAKPVPVNPNNFKNYKIGNLIVSLAGVFCNVLTAI
                     LCVIINKYVHMYAINTIAGYVLLYSMGFAAFNLLPIPPLDGWGVISTFVPYKWNEYLY
                     KFESMSYIILLIALFTGMYRIILSPIYTVLLKIVYLFV"
     gene            7342..8061
                     /locus_tag="PC494_003317"
     CDS             7342..8061
                     /locus_tag="PC494_003317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HDF3913788.1"
                     /translation="MKYNIQLQVYEGPLDLLYDLITKHKIDIKDISIIDITKQYLNYL
                     KMLDKMDLEITSEFITMASKLLEIKSKYLLYKQKDEEEDPRIELMEKLEEYRKFKVAS
                     QDIKENITYVNERFYRNKEEIIIDDNVDLEDISIEAIKNILPYIFKVKTSQIENANDE
                     KLDKIVRKKIISVEEKILYIRDIIKDKIEVTFTNIIKSYENDEIIATFLSILELIKEK
                     EIVVVQDIFFDDILIRKSSEC"
     gene            8063..8602
                     /gene="scpB"
                     /locus_tag="PC494_003318"
     CDS             8063..8602
                     /gene="scpB"
                     /locus_tag="PC494_003318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SMC-Scp complex subunit ScpB"
                     /protein_id="HDF3913789.1"
                     /translation="MKREDIKYIIESVMFAYGEPISIKELNYIINKELSSKEIEIMLN
                     LLIEEYREQNRGIQIIKLENKYQMCTNKDYAEYIKKIIEPKKKKSLSQATLETLTIIA
                     YKQPITKVEIEDIRGVKCDKVLQTLFENELIREAGRLNKIGKPIIYKTTDEFLKLLNI
                     ESLEELPPIENYQEVATNE"
BASE COUNT         3429 a          979 c         1416 g         2892 t
ORIGIN      
        1 aataaattaa atttatttaa atgtcttgac aaaaaatgaa ttatcaatta caatattatt
       61 taataaagat tatcaattga aaatagtaag ggtgatgtta tggcaaatac aatggattta
      121 ttaaaagaca agttaaaaga aactggtttt aagattacgc cacaaagaag agcaatagtt
      181 gaaatattgc ttaaacatga ccattcacat ctaagtagtg aggaaatcta tgatttagtt
      241 agggttgact gtcctgaaat aggcttagct actgtatata gaacaatgca gctattggat
      301 gaaataggat taatatcaaa actaaactta gacgatggat gtataagata tgagattagt
      361 ctacataaag aagactgtca taatcatcat catcttattt gtaaaaattg tggaaagata
      421 atggaagcta aagaagacct tttagacaat atagaaaaag agatacaatc attgtacaaa
      481 tttaaaatac ttgatcatga tgttaaattt tatggactat gtgacgagtg taatggagta
      541 agcgattcag aagaataaac ttctattgct taatgtcgat ggaagaatag tatagaactt
      601 ttatattcta tgctattctt ccatttttta ttataaacca tctacaaaat gcaaatatac
      661 agttttcaag atgcttatag ttttaatatt gaaaatataa ttaatcctat aagtacaaaa
      721 atgaatgatt tttctatgaa attactaaat ggtcctccaa cagttaaaaa acctaaagaa
      781 attttctttt cgcttagcgg ataaaaaatt ggtattcctt gctttgtaaa taaatctcct
      841 aaaaacatat gacttgcata accaatcgta ccataaaaag ataaattatt aatattagtg
      901 attaattcta tctgttttag taaaaaatat actattatag ttgcaaatat gctatgagaa
      961 aaacttctgt gctttaacca gggaaaaatt gacaacatta gacaaaaaat tgtaaaatat
     1021 atttcaactt ctatgatgta taagcatata gctaatagta taaatattaa tgatagaaaa
     1081 acttttctta gaaatgtgtg ggttagtttt gcttcaataa ttataattgc aacaaatgta
     1141 attattgcgc ttaaataaaa attatcattt atatttattg aaataaagaa aataataata
     1201 ttaacagcat atataaaaat tctatatatg tatttggata cattgttttt tagaatgaaa
     1261 tttgagacca tagaattaga tttatccaaa tcgggtagta cagcaaaagt agctgaaact
     1321 aaaatatcaa ctaaagatat aggaatttta aatattaaag atgtttggat agctgttaag
     1381 attcctattg cacaatgagt tttaccacgc ataaatcctc ctaaattatc cgatattaaa
     1441 tcatataata tttagaggat atcaaaataa aataggtttg tcaaaataat acgttaaatg
     1501 tattttaaat atagcttaaa atatgatacg aattatggta caataagaat aactggtagc
     1561 gagtgcgtga tttgatatta tttatgattg tagaacgtgt taaaaaatta aatagacaga
     1621 aggagatgat gcaattgttc aaaaagaaca ccaacaagat aaaggtaatg gccttgggtg
     1681 gacttaacga agttggaaaa aatatgactg ttgttgagta taaagatgaa ataattgtta
     1741 tagatgctgg acttagtttt ccagaggatg aaatgttagg agtagatata gttataccag
     1801 atataactta tttagtaaaa aatagggata aaataaaggg tatatttatt acacatggac
     1861 atgaagacca tataggagct cttccatata tattaaagaa aataaatgta cctgtatatg
     1921 gggcaagact tagtataggt cttatacaag taaaacttaa agaacataaa atgaataatg
     1981 ttaagttaaa tgttataggt cctagacaag ttataaagct tgataatatg gaagtagagt
     2041 ttttgaaaaa taaccatagt ataccagatg cttactctat tgcaatacac acagaccaag
     2101 gtataatata ccacacagga gattttaaga ttgatttgac tcctattgat ggagatgtta
     2161 tggatatgca tagaatctgt gagttgagca aaaaaggagt tcttttaatg ctggcagata
     2221 gtactaatgc agaaaaacca ggatttacta tgtctgaaaa gactgttggg gtaggtcttg
     2281 acgaattatt tgcaaaagga aatggcagaa gaattatagt tgctaccttt gcatccaaca
     2341 tacacagatt acaacaaata ataaatactg ctgaaaagtt taatagaaaa gttgctatat
     2401 caggtcgctc aatggtcaat gtagttggag ttgcaaaaga attaggatac ctagatattt
     2461 ctgatgacat gcttatagat ttaaatgata tatgtaagta tgaagatagt gaattagtga
     2521 taataacaac tggttcacaa ggtgaaccta tgtcagctct tgctagaatg gctttttcag
     2581 agcacaaaaa agtagaaata aagagtggcg atttagttat aatatctgct catccaatac
     2641 caggaaatga aaaattaata tcaagagtaa tcaatttctt atttgaaaaa ggagcagaag
     2701 tagtatacag tgatatagct gatatacacg tttctggaca tgcctgtcaa gaagaattaa
     2761 aacttataca tgcattagtt agaccaaagt tttttatgcc agctcatggt gaatatagaa
     2821 tgttaaaaag acatgctgaa atagctgaac agcttggtat ggataaagaa aatatttttg
     2881 tcatgcaaac aggagatgtt ttagaattag ataaaaattc tgctaaggta gcaaaccgta
     2941 tacaaacagg aaacatatta gttgatggtc taggagtagg cgatgtaggt aatatagttt
     3001 taagggatag aaagcattta tcagaagatg gtcttatgat agttgtagtt actatttcca
     3061 aggatgaggg taaggtctta gcaggtccag atataatttc cagaggattc gtatatgtaa
     3121 gagagtcaga agatttaatg gatggagcaa aggatataat taagaatgtt ctaaatgaat
     3181 gtgaagagaa aaatattaaa gaatgggctt atttaaagaa taatattaaa gaaaacctaa
     3241 aagaatattt atatcaaaaa actaaacgaa atccaatgat acttcctatc ataatggaag
     3301 tataatataa aaaaactata aatttgaaaa ttagacctct tgtaattttt aaagtaatat
     3361 caaaaatcca attgatatta tcttaagaat tacaagaggt ctttttaata ctcattttaa
     3421 aaaaatatat attacataaa ataccaatta taacaatctt ttattagtaa aaactactta
     3481 tatataaatt ttactgatag gaggattctt atggatgatg tttcaagaca aaatgctata
     3541 aaagctttaa aacaaacaaa aatggaaata gcaggagagt atggaatgaa ttatgaagat
     3601 gcttttgaaa taatagaaaa tgcgtctaat aaaggtgttt tagaaggtta ctttaaaaag
     3661 cttgaaaaga aaaaaaattt aggtcaaggt atatctaggc atttagaata aaaaaagtta
     3721 aatgtgagaa aataagttta aataaacttt aagaggtgac atcgatgaaa aaattagcta
     3781 gtactgcttt ggctatatta attgcgctta ctcctttaag cttttctttt gcaaataata
     3841 aggaaaatgc tgatgccaac caactaaata tatcttcaaa atcagcaatt ttgatggatg
     3901 ttggtagtgg acaaatttta tatgaaaagg atgctcataa aaagcttcct cctgctagtg
     3961 taactaaggt aatgactatg ctacttatag tagaagcttt ggattcaggc aagattaagc
     4021 ttgatgatga agttcaagta agtgaaactg catctagtat gggtggtagt caaatattcc
     4081 tagagccagg agaaactcaa aaggttgata cattattaaa aggtatagct gttgcttctg
     4141 caaatgatgc ttgtgttgct atggctgaac acttagctgg aagtgttgaa ggatttgttg
     4201 atagaatgaa tgctaaagca aaagagttaa atatgaatga tactcatttt gcaaatacaa
     4261 atggacttcc agttgcaaac cactatacat ctgctcatga tatagcttta atgtctagag
     4321 aactattaaa acacgaaatg ataagtaaat acttaactac atggatggat aaggttgtag
     4381 tagggaagaa acaagttaca gtaggtcttg caaatactaa taaacttata aagcattatc
     4441 aaggagcaac tggtgttaaa actggtttta ctcaagaagc aaaatactgt ttatcagcat
     4501 ctgcaaagag aggtaatact catctagttg ctgcaacttt aggagcagag acttctccag
     4561 aaagatttaa tgatgcctct agccttttaa actatggatt tgctaattat gaaagtgtta
     4621 agttatgtag taaaggtgat aatatagcaa cacttacatt ggataaggct gatgaaaaca
     4681 aagttaaatt ggttgctaaa gaagatttaa atgctcttat taaaaaagga agttctaaag
     4741 aatttgagaa gaaaattgaa atagtaaaaa atcctaagat gccaattaaa aagggaactg
     4801 ttttaggaaa aataaagata tgtaaagata aaaaagtaat aggcgaagtg gaattgataa
     4861 atactaagga tataaataag gcaagctatc tacaaatgct tcaaagaata attgataata
     4921 tgatataaat aattatcaga tgaaatataa ttataataca caaagatatg attataatac
     4981 acataaaaaa tacccttatg taattatttg ccataggggt atttttattt accatataga
     5041 agtattttat aatcttatga tttttataga aatatagaaa agtttatgta tcttaaaata
     5101 tcatttgatt taatatcata tatagggttg tttaacaatt atctaagtaa aggcatacta
     5161 ccagtaagtt tattcacttt ctttttattc ccataaattg ctatcccaaa atactgtaac
     5221 tcatcttctg gaacactagc aatcttttgt gtaaattctt cataaagatt gcaactttgt
     5281 gctacatctg aaaaatctac aacagttaaa tcgttaaatt ccaaagtata taatttttta
     5341 cgtaaatctt ttattatttc tttgtttcct tttaaaatag gtacaggaat gtcaataatt
     5401 cctaagtggc tattacctgt tttgtcaatt acatctgggc caacagtttc tggggcatgt
     5461 tttcctagtg taattcccat tatagctgct gtattggata taattcccat tggtaaattt
     5521 tcgtctatta ccatgacaca ttttgaattt ttagtttcca tttttatttc tcctttttac
     5581 cttatttaaa gttgtttgaa tcatcattta taaatatatt ttgatactgc tttggtgtaa
     5641 gaccaataaa attcttaaaa aagtttgtaa agtgactttg gtctacaaat cctgtttgta
     5701 tcgcagcatc tataggttct acgccttttt ctaaaagctt tttagctttg tttacccgta
     5761 tattttctag gtatctatat ggtgtaatac cttttaattt cgtaaaatta cgaagtagag
     5821 agtacttatt catacctgct atagtgctta attcgtcaag tactatatgt tcagcataat
     5881 tattttctag ataatcacat actgcttgaa tttctatatt tgtattttcc aagttagatt
     5941 gcaaatttgg ctctgtatgt tcttcaatta attgttcaat taggaagaaa aaaagctctt
     6001 cctttttaaa atccaattct tcttccatga ttatatagtg taattcttgt agtagaggta
     6061 ctagctcact gcgaaatata acaggttgat taaattttgg taaataattt ttacctgtaa
     6121 tttcaaagac ggtttttttc attatttctg gcttaatatt aatacatctg taatcaagta
     6181 ctttatcatc tatttgttca caagtatgac tatcaaaagg gttaaaaagt agcaaatctc
     6241 cagtacttgt ggtatactct ttatttttac aagataaata tctttgacct ttttctataa
     6301 aaccaattac ataatgttca tgaaaatggt ttgggaattt ttgcattatg cctttaaatc
     6361 tatatgcttc aatttttaat tccctatcaa agcatactgt gcgttcttct tgtctcactt
     6421 aggtaacctc ctttcatgtt atacaaagtg taacacatat ttttttatac ttcttgtata
     6481 atattgacta agagacaata atgtcaattc atgtcaatat aatattatac ttacagtagg
     6541 tgtaattatt atattttcac aatgaatatg atataataat aaaagttata aaataaaaag
     6601 caaattttaa ttttatgcct agaagttaaa attattataa tgtaaaataa ttttgattat
     6661 aagctattta attgttataa taatattaaa aatttaattt aggagatgta cattaatgtt
     6721 aagtatgaat ataggagaaa tagtagcaag tttagttggt atagctatgg caatatcaat
     6781 acatgagttt ggccatgctt attcagctca cttattgggg gatgatacag ctaaagctta
     6841 tggtagaatg acattaaatc ctgtaagaca tgttgaccca ataggtcttt tggctatgtt
     6901 tatccttaag atagggtggg caaagccagt accagtaaat ccaaataact ttaaaaacta
     6961 taagatagga aacctgatag tttcacttgc aggcgttttt tgtaatgttt tgactgctat
     7021 actgtgtgta attatcaata agtatgtgca tatgtatgct ataaatacaa tagctggata
     7081 tgtgctttta tatagtatgg gatttgcagc ttttaactta cttccgatac ctccacttga
     7141 tggatgggga gttatatcta catttgtacc atataaatgg aatgaatatt tgtataaatt
     7201 tgaaagtatg agttatataa ttttattaat tgctttattt actgggatgt atagaataat
     7261 actatcacca atatatacag tgttgctaaa aatagtatat ttatttgttt aatataataa
     7321 acagattaaa gagggattga tatgaagtat aatatacaat tacaagtcta tgagggacca
     7381 ttagatttac tttatgattt aataacaaag cataaaatag atataaagga tatatccata
     7441 atagatataa ctaagcagta tctaaattat ttgaaaatgc tagataaaat ggatttagag
     7501 ataactagtg aatttataac tatggcatca aaacttttag agataaagtc taaatatctg
     7561 ctttataagc aaaaagatga agaagaagac ccaagaatag aacttatgga aaagttagaa
     7621 gaatatagaa agtttaaggt agcatcacaa gatataaaag aaaatataac ttatgttaat
     7681 gagagatttt atagaaataa agaagagata attattgatg acaatgtgga tttagaagat
     7741 atatcaattg aagcaataaa aaatatactt ccatacatat ttaaagttaa aacatcacag
     7801 atagaaaatg ctaatgatga gaaactagat aaaatagtaa ggaagaaaat aatatctgta
     7861 gaagaaaaaa tattatatat aagagatatt ataaaagata agattgaagt tacttttaca
     7921 aatattataa aatcatatga aaatgatgaa ataatagcta cttttttatc tatattagag
     7981 cttataaaag aaaaagaaat agtcgtagta caagatatat tttttgatga tattctaata
     8041 agaaaaagtt cggagtgtta aaatgaaaag agaagatata aagtatatta tagaatctgt
     8101 tatgtttgca tatggggaac caataagtat aaaagaatta aactatataa taaataaaga
     8161 actttcatca aaagaaatag agattatgtt aaatttactt attgaggagt acagagaaca
     8221 aaatagaggt attcaaataa tcaagttaga gaataagtac caaatgtgta caaataaaga
     8281 ttatgcagaa tatataaaga agattattga accaaagaaa aagaaaagtt tgagccaagc
     8341 tacattagaa actcttacta taattgccta caaacaacca ataacaaagg tagaaataga
     8401 ggatataaga ggagtaaaat gtgataaggt attacaaact ttgtttgaaa atgaacttat
     8461 aagagaagct ggtagattga ataagatagg gaaaccaata atttataaaa caacagatga
     8521 atttttaaag ttgttgaata tagaaagtct tgaagaattg ccacctatag aaaattatca
     8581 agaagtggca acaaatgaat aaaaatataa aatcacaata atttagtatg taattttaaa
     8641 ttttaaaaga tttaaaatgc tctaagttgt tgtgtttttt tgtataaata taaaattata
     8701 attctcttaa aataaa
//
LOCUS       DAMKNB010000120         8558 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.126, whole genome shotgun sequence.
ACCESSION   DAMKNB010000120 DAMKNB010000000
VERSION     DAMKNB010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8558)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8558)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8558
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.126"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            75..2252
                     /locus_tag="PC494_003319"
     CDS             75..2252
                     /locus_tag="PC494_003319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-dependent oxidoreductase"
                     /protein_id="HDF3913790.1"
                     /translation="MYNKYNNLYLLLGKENVNMDSYRQLKAKIPCKETGIEIKRTLCD
                     ICSPGVHCGIDAYVKDGKVIKIEGTKEHPMNKGLLCTKGLCNREYIYREDRIKTPLKR
                     IGKRGEGKFKPISWDEAYREIAEKLNRVKSEYGAKHVAFFTGYGKWYRPFLQRFASSF
                     GSPNYGTESSSCSTSAQMAGNVATGRNFTMQDMENAKTYLGWGFNPYYSKFLNSVNLI
                     KLKEKGLKFIIVDPRITPTTQKLADLHLRIKPGTDGALALGMANLFIQKNLIDREYIE
                     KYVHGFNEYKEYVKLFDLDTVSRITGVSKDNIVKAVEMLSQGPFCINESAAPIVHHQN
                     GFQNYRAMMSLSAITGNYDRIGGNIPKQDYFAGKIGGFQTLEKEFVKEVLPKNINERI
                     GGERFPLWNEMVTQFQAMDLPRQIEEKTPYEIRALFCHGINARMFPNSGRLFKALNSV
                     DFFVNIDLFMTDTSKYADILLPACTSFEREECKSYPGGYITYTKKVIDKLYDSKSDVE
                     ILSDLANAMNIDDDLLKAGYEASIRHMFKNTCVDVDKLKESDLPLKCKDFKPYIVGSY
                     TREGYDTSTSRFELKSTIIEKYKDFGLDALPTYRGFNDNIDDEYTHLLTSGARISNAL
                     HSRLHDIKLSRILKNEASCDISSLDAKELGVISGDYIKITTKIGSLDVKVNVTDRVLY
                     KNIHMYHGYREADINSIICDNFDPYSGFPAYRSCKCKIEKMNR"
     gene            2266..2688
                     /locus_tag="PC494_003320"
     CDS             2266..2688
                     /locus_tag="PC494_003320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HDF3913791.1"
                     /translation="MKSLFKFNKELCTACGACLLACIDQNDNNIDNGELFRHVFTIEE
                     GENIEYFSLACIHCNEPKCLGVCPKNCFKKEEGFVVLDNQNCIGCKLCEKACEYGALI
                     YGNDGKANKCNGCIERYKCGMDSPCVMVCPTGALKFNK"
     gene            3096..3899
                     /locus_tag="PC494_003321"
     CDS             3096..3899
                     /locus_tag="PC494_003321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HDF3913792.1"
                     /translation="MKKLKLIIMFALVSALLVTGCSSGNNKNKEEQKVIRVATSGTYY
                     PFAFKDKDKLKGFEVDFWDEFAKRTNCKVEWVLTDFSGLFGLLEADKADVVSAQLTAT
                     PEREKKYAFSDAYNYSGTNIIVREDDTSIKSIDDLVGKKVGVGTGAVANEILKEKYPN
                     DEIKIVNYSSATLKGNYQDLEMGRLDAVVAQDVEALIAIKEQKLNLKMIEPPIQFGAC
                     SFALQKNEKGEKWTKEINEVIEEMYKDGTLTKISENWLGKDITKEPINE"
     gene            3892..4560
                     /locus_tag="PC494_003322"
     CDS             3892..4560
                     /locus_tag="PC494_003322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HDF3913793.1"
                     /translation="MSNFNFEFCLSIFPFLIKALGITILISIVSFFLSILLGVILAFF
                     TQTKSKVLQYITRVYVSFFRGTPLLIQIFFFYFGFPMIFSFMKDCSPYLAIVICLGVN
                     SSAYMAEIIRASIESVDKGQQEACYAFGLSKYQSMVKIILPQAATSAVPPIVSCTLDI
                     IKGSSLGLTIGIQDLMGVAQVEAASSFKYFEIYMITILIYWAVSIILSNIQSKVEKRI
                     RRAY"
     gene            4796..5458
                     /locus_tag="PC494_003323"
     CDS             4796..5458
                     /locus_tag="PC494_003323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HDF3913794.1"
                     /translation="MAFNMKYFLELFPTIMKSFNVTVILAISSLVFSLIIGTIVALSS
                     YYKVKVLNQICKVYVSIFRGTPLMPQLFFLYFGLAYMSDFVKNMDPVFATSIVLSLNM
                     GAYMSETIRASILSIDTGQIEAAYAMGLTNLQTMKRIVIPQAVRVALPSLFNNFIDLI
                     KGSSVAFVVGVNDIMGAAKSQGALSFKFFEVYGAVMVIYWCIITPLGWGQKKLEKKIS
                     NY"
     gene            5518..6315
                     /locus_tag="PC494_003324"
     CDS             5518..6315
                     /locus_tag="PC494_003324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HDF3913795.1"
                     /translation="MIKRNIIKCLVAVLSLTFVITGCSKKEEVKNEKVITVASSNSAD
                     PYSYVDNGEHKGFEVDMWKEIGKRSGYKIKMEPTGFSSIFGMLDSGKVDVAANFFGMS
                     KERLEKYDASIPYGSDSVCIAVKDGNNEINKLEDLKGKVVAVSEGSQGQQVATSVNKD
                     NLFQEKVYGDGTSGLQDLDLGRVSAWIDAELTIVGDAKKANMKVRVLDKKLSATNIAY
                     FFKKNDDKSKTIKEDVNKAIEEMLADGTVKKISEKWFGMDVSADIQK"
     gene            6433..7623
                     /locus_tag="PC494_003325"
     CDS             6433..7623
                     /locus_tag="PC494_003325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HDF3913796.1"
                     /translation="MEVLQMIETKIKSIALKNREKIIKIRRQIHSNPELAFKEYKTSK
                     LIKEELNKLNIEYINIAGTGVLATIKGKNNGGKTILLRADMDALPIKEENDLEFKSIN
                     DNMHACGHDAHVSWLLGTAMILNDIKEELNGNVKLLFQPGEEKGGSDIVIKENVLEGV
                     DALATGHCWPTIESGKIGIARNCAMAATNTFEITIIGKGGHGAEPHNCIDPIAVGNAV
                     YSSIQQIVSRKIDPVVPVVVSVCSFNSGVSKNIIPDVCTLQGTIRAISKEQVIEVSKI
                     LEYIVKNVCKAHGADCKFEKSTGGDAVINDKNMIEIGRESACKILGAENVEIIDFPAM
                     TGEDFAIYMKEKPGLFMYIGVGDKEKNINYRLHSNKFNIDEKCLSIAPSLFSQLTVDY
                     LCQL"
     gene            7732..8481
                     /locus_tag="PC494_003326"
     CDS             7732..8481
                     /locus_tag="PC494_003326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HDF3913797.1"
                     /translation="MIKVENLHKSFKGTEVLKGINLEISQSEVVAILGSSGTGKSTLL
                     RCLNYLVEPTKGKIMIGDVKVDVEKATKKDITNLRKHTSMVFQNYNLFKNKTALENVM
                     EALIVVHKKSKKEAREISLKLIDKVGMLDRKDFYPSKLSGGQQQRIGIARAMAVNPNV
                     ILFDEPTSALDPELVGEVLSVIKSLAKEGITMLIVTHEINFAKEVADKIIFMDNGVIA
                     EEGTPDEIFNNPKNERTAKFLNIIRKEEVFS"
BASE COUNT         3397 a          858 c         1583 g         2720 t
ORIGIN      
        1 aaaatcttat tattaaaaat attcttagaa attacactat ataaaatata aagtatgata
       61 tttgaataaa aagaatgtat aataagtata ataatttgta tttattattg ggaaaggaaa
      121 atgttaatat ggatagttat agacaactta aagctaaaat accctgtaag gaaacaggta
      181 tagaaataaa gaggacttta tgtgatattt gttctccagg agtacattgt ggaattgatg
      241 catatgttaa agatggtaaa gtaataaaaa tagaaggtac aaaagaacat ccaatgaata
      301 aagggttgtt atgtaccaaa ggtctttgca atagagaata tatctataga gaagatagaa
      361 taaaaacacc tctaaaaaga attggaaaaa gaggtgaagg aaaatttaaa ccaatatcat
      421 gggatgaagc ttatagagaa atagcagaaa aattaaatag agtaaaatct gagtatggag
      481 caaagcatgt agcttttttt acgggttatg gaaagtggta tagacctttt ttacaaaggt
      541 ttgcatcttc atttggttca cctaattatg gtacagaatc tagttcatgt tcaacatcag
      601 cacagatggc tggaaatgtt gctactggaa gaaactttac aatgcaagat atggagaatg
      661 caaaaactta tttagggtgg ggatttaatc catactactc taaattttta aatagtgtga
      721 atctaataaa attaaaagaa aaaggtctaa aatttataat tgtagaccct agaataacac
      781 cgacaactca aaaactagca gatttacatt taagaattaa acctggaact gatggagctt
      841 tagctcttgg aatggcgaat ctatttatac aaaagaattt aatagataga gaatacatag
      901 aaaagtatgt acatggattt aatgaatata aagaatatgt aaaattattt gatttagata
      961 ctgtaagtag aattacagga gtttctaaag ataatatagt aaaagctgtt gagatgttgt
     1021 cacaaggtcc attttgtata aatgaaagtg cagctccaat agttcaccat caaaatggat
     1081 ttcaaaatta tagagcaatg atgtctttat ctgctataac aggtaattat gatagaatag
     1141 gtggaaacat accaaaacaa gattactttg ctggtaagat aggtggattc caaacactag
     1201 aaaaagagtt tgtaaaagaa gttctaccta aaaatataaa tgaaagaatt ggtggagaaa
     1261 gatttcctct atggaatgaa atggtgactc aatttcaagc tatggattta cctaggcaaa
     1321 tagaagaaaa gacaccatat gaaataagag ctttgttttg tcatgggata aatgctagaa
     1381 tgtttcctaa ttcagggaga ctttttaaag cgttgaatag tgtagatttt tttgtgaata
     1441 tagatttatt tatgacagat acatcaaaat atgcagatat acttttacct gcatgtacat
     1501 catttgagag agaagaatgt aagagttatc caggagggta tattacatat accaaaaaag
     1561 ttattgataa attatacgat tcaaaatcag atgtagaaat actttcagat ttagcaaatg
     1621 ctatgaatat agatgatgat ttattaaaag caggttatga agcaagtata agacatatgt
     1681 ttaaaaatac atgtgtagat gtagataaac ttaaagaaag tgatttacca ttaaaatgta
     1741 aagattttaa gccatatata gtaggttcat atacaagaga agggtatgat actagcactt
     1801 ctaggtttga attaaaatct acgattattg aaaaatataa agattttgga ctggatgcac
     1861 taccaacata tagaggattt aatgataata tagatgatga atatactcat ttattgacat
     1921 caggagcaag aatttcaaat gcactacatt caagacttca tgacatcaaa ctttcaagaa
     1981 tattaaaaaa tgaagctagt tgtgatattt ctagcttaga tgcaaaagaa ttgggtgtta
     2041 tcagtggaga ttatataaaa ataactacta agataggaag tttggatgta aaagtcaatg
     2101 ttactgatag agtcttatat aagaatatac atatgtatca tggatataga gaagctgata
     2161 taaatagtat tatttgtgat aattttgacc cttatagtgg attccctgcg tatagaagtt
     2221 gtaagtgtaa gattgaaaaa atgaatagat aaatggagag atataatgaa aagtttattt
     2281 aaatttaata aagaattatg tacagcatgt ggagcatgtt tgcttgcatg tatagaccaa
     2341 aatgataata atatagacaa tggtgaactt tttagacatg tatttacaat agaggaaggt
     2401 gaaaatatag aatatttttc attagcatgt atacattgta atgagccaaa atgtttaggt
     2461 gtatgtccta aaaattgttt taaaaaagaa gaaggattcg ttgtattaga caatcaaaac
     2521 tgtatagggt gtaaactttg tgaaaaagct tgtgaatatg gagccttaat ttatggaaat
     2581 gatggtaagg caaataagtg taatggttgt attgagagat ataagtgtgg tatggattca
     2641 ccttgtgtaa tggtatgtcc tacaggagca ttaaaattta ataaataaat taaatataga
     2701 gaatgactta tacttaggta taagatattt ttacaaaaag ctgtattgag tttgttataa
     2761 tgaaaactca atatagcttt tttatggata tagttggata ctataatgtg attcttagta
     2821 atagtttttt gctattggac aaagactgta aaacatatta aacttatgtt gttcaaagtc
     2881 gaagtataat ataataacta gaaaattggt ttatagtgct ataaaagcaa atttagtaag
     2941 gtataaaatc agaggcaatc ctttactata atatcaatat ttgggagttc tgttattgca
     3001 gagctattaa acaattataa tggtacaagt gattcaacct ttgaaaatgt attatataaa
     3061 aaattaaaat aagattaaaa aggagagaat aaattatgaa aaaacttaaa ttaattatta
     3121 tgtttgcctt ggtatcagca ctgttagtta caggatgttc atcaggaaat aataaaaata
     3181 aagaagaaca aaaagttata agagttgcaa catcaggaac atattaccct tttgctttta
     3241 aagataaaga taaacttaaa gggtttgaag tagatttttg ggatgaattt gctaaacgaa
     3301 ctaattgtaa agttgaatgg gtattaactg attttagtgg attatttgga ttattagaag
     3361 ctgataaagc agatgttgta tctgctcaac ttactgcaac acctgaaaga gagaaaaaat
     3421 atgctttttc agatgcttat aattatagtg gaacaaacat tattgttaga gaagatgata
     3481 ctagtataaa atcaatagat gatttagttg gcaagaaagt aggtgtgggt actggagcag
     3541 tagcaaatga aatattaaaa gaaaaatacc caaatgatga aataaaaata gtaaattatt
     3601 caagtgcgac tcttaaaggg aattatcaag acctagaaat gggaagatta gatgcagtag
     3661 ttgcgcagga tgttgaggct ttaatagcta taaaagaaca aaaattaaat cttaaaatga
     3721 tagaacctcc aattcaattt ggtgcctgtt cttttgcgct tcaaaaaaat gaaaaaggtg
     3781 aaaaatggac aaaagaaatt aacgaagtaa ttgaagagat gtataaagat gggactttga
     3841 ctaaaatatc tgaaaactgg ctaggaaaag acattactaa ggagcctatt aatgagtaat
     3901 tttaattttg aattttgtct aagtatattt ccatttttga ttaaagcatt gggaataaca
     3961 atactaatat ctattgtttc atttttttta tcaatattat taggtgtaat acttgccttt
     4021 ttcacacaga caaaatcaaa agttttacaa tacataacaa gagtgtatgt ttcattcttt
     4081 agaggaacac cacttttaat tcaaatattt ttcttttatt ttggatttcc aatgatattt
     4141 tcttttatga aagattgttc accttattta gcaatagtaa tttgtttagg tgtaaattca
     4201 tctgcatata tggctgaaat tatacgagca tctattgaga gtgttgataa aggacaacag
     4261 gaagcatgtt atgcttttgg gttaagtaaa tatcagtcaa tggttaaaat aattctacct
     4321 caagcagcta catctgcagt acctcctatt gtaagctgta cactggacat aattaaaggt
     4381 tcttctttag gtttaactat aggaatacaa gatttaatgg gagtagctca agtagaggct
     4441 gcttcaagtt ttaaatattt tgagatatat atgataacga tattaattta ctgggcagta
     4501 tctataatat tgagtaatat acaaagcaaa gttgaaaaaa gaataagaag agcatattag
     4561 atttcaatat ttaaaaatgg gatgatatag atatattatt acttgtaaat aaatttttaa
     4621 ttttagaaaa ataaacttag taatctaaat tattgagaaa atatagtatc aaaatggact
     4681 gtataatcaa gttaaaaaat agtttttcta ttgaaaaaat aaataaaatt ctattgtaat
     4741 ttaatatgcg ataaagtttt ataaaaaaca acattaagct agggggactt attttatggc
     4801 ttttaatatg aaatattttt tagaattatt tccaacaata atgaaatcgt tcaatgtaac
     4861 tgtgattttg gcaataagtt cattagtatt ttcattaatt ataggtacaa tagtagcgtt
     4921 atcatcttat tacaaagtga aagtattgaa tcaaatatgt aaagtatatg tatctatttt
     4981 tagaggtaca cctcttatgc cacagttatt ctttttatat tttggactag catatatgag
     5041 tgattttgtt aaaaatatgg acccagtatt tgcaacatct atagtactta gtttaaatat
     5101 gggagcttat atgtctgaaa cgataagggc atctatactt tcaattgata caggtcagat
     5161 agaagcagca tatgcaatgg gattaacaaa tttacaaaca atgaaaagga tagtgatacc
     5221 acaggccgta agagttgcac tgccatcatt attcaataat tttatagatt taattaaagg
     5281 gtcttctgta gcttttgttg ttggagtaaa tgatataatg ggtgctgcca aatcacaagg
     5341 agcgttgagt tttaagtttt ttgaagtgta tggagcagtt atggtaattt actggtgtat
     5401 aataactcct ttaggttggg ggcaaaaaaa attagaaaag aaaataagca attattaagt
     5461 tattaagaaa atacataaaa gtatttttat ataaaaaatg gtgtgaggag aagagatatg
     5521 ataaaaagaa atattataaa atgtttagtg gcagttttat cgttaacgtt tgtaattact
     5581 ggttgttcaa aaaaagagga agtaaagaat gaaaaagtta taactgtagc ttcatctaat
     5641 tcagctgacc catattctta tgttgataat ggtgagcata agggttttga agttgacatg
     5701 tggaaagaga ttggtaaaag aagtggatat aagataaaaa tggaaccaac aggttttagt
     5761 tctatatttg gtatgttaga ttctggtaaa gttgatgtgg cagccaactt ctttggaatg
     5821 tctaaagaaa gattagaaaa atacgatgct tctatacctt atggttctga ttctgtgtgt
     5881 atagctgtaa aagatggaaa taacgaaatt aataagcttg aagatttaaa gggaaaagtt
     5941 gtagcagttt cagaaggttc tcaaggtcaa caggttgcaa ctagtgttaa taaagataat
     6001 ttgtttcaag aaaaggttta cggtgatgga actagtggtc ttcaagattt agatttggga
     6061 agagttagtg catggattga tgcagagctt actattgtgg gagacgctaa aaaagctaat
     6121 atgaaagtaa gagtattaga taaaaaatta tcagctacta atatagcata cttctttaag
     6181 aaaaacgatg ataaatctaa aacgataaaa gaagatgtaa acaaagcaat agaagaaatg
     6241 cttgcagatg gaacagtgaa aaaaatatct gaaaaatggt ttggaatgga tgtaagtgct
     6301 gatatacaaa aataaatact ttaaaattaa aatgtaaaac tgtgataact atagataagt
     6361 atactaaatt tatctatagt tatctgtgta ttacaatgta tttagattag tctttataaa
     6421 tcaaaatgag ttatggaggt attgcaaatg attgaaacta aaataaaatc cattgcacta
     6481 aaaaatagag aaaaaattat aaaaataaga cgacagatac acagtaatcc agagttagca
     6541 tttaaagaat ataaaacatc taaacttata aaagaagagc taaataaact taatatagaa
     6601 tacataaata ttgctggtac aggagtatta gctactataa aaggaaaaaa taatggtgga
     6661 aaaactatat tactcagagc ggatatggat gctcttccaa tcaaagagga aaatgattta
     6721 gaatttaaat caataaatga taatatgcat gcttgtgggc atgatgcaca tgtttcatgg
     6781 ttgttaggaa cagcaatgat tttaaatgac ataaaagaag aattgaatgg aaatgtaaaa
     6841 ttactatttc aacctggcga agaaaaaggt ggttctgata ttgtaattaa agaaaatgta
     6901 cttgaaggtg tggatgcatt agcgactggt cattgttggc caactattga gtcaggaaaa
     6961 attggaatcg ctagaaattg tgctatggca gcgactaata cttttgaaat aacaataatt
     7021 ggcaagggtg ggcatggagc agagcctcat aattgtatag acccaattgc agttggaaat
     7081 gcagtatatt catccattca acagatagtt tcaagaaaaa ttgacccagt tgtacctgta
     7141 gtagtgtctg tttgttcttt taattctggt gtttctaaaa atataatacc agatgtatgt
     7201 acacttcaag ggactattag agcgataagc aaggaacaag taattgaagt aagtaaaatt
     7261 ctagaatata tagtaaaaaa tgtatgtaaa gcacatggag cagattgcaa atttgaaaag
     7321 agtacaggag gagatgctgt tataaatgac aaaaacatga tagagatagg aagagaaagt
     7381 gcttgcaaaa tacttggagc tgaaaatgtt gaaataattg attttcctgc aatgacaggt
     7441 gaggattttg ctatttatat gaaagaaaaa cctggtttat ttatgtatat aggtgtagga
     7501 gataaagaaa aaaatataaa ttacagattg catagtaaca agtttaatat agatgaaaaa
     7561 tgtcttagta tagcaccttc attattttca caacttacag tagattattt atgtcaacta
     7621 tagagtacat tcataaaaat atatttagcc tatttttaaa tttaatgcta gtatattaat
     7681 tttgatgtag aacatattat ttattatatt tatttaaaaa ggtggataac aatgataaaa
     7741 gtagaaaatt tacataaaag ttttaaaggg acagaagttc ttaaaggtat aaatttagag
     7801 ataagtcaaa gtgaagtagt agctatactt ggatcatctg gaacaggtaa atctacgtta
     7861 cttagatgtt taaattattt agttgagcct acaaaaggaa agataatgat tggtgatgta
     7921 aaagtagatg tagaaaaagc aacaaaaaaa gatataacca atttaagaaa acatacatct
     7981 atggtgtttc aaaattataa cttatttaaa aataaaacag cattagaaaa tgtaatggag
     8041 gcattgatag tagttcataa aaagagtaag aaagaagcta gagaaatatc tttaaaatta
     8101 atagataaag taggtatgtt ggataggaaa gatttttatc catcaaagtt gtctggggga
     8161 cagcaacaaa ggataggtat agcgagagcg atggcagtaa atccaaatgt aatattattt
     8221 gatgagccta catctgcact tgacccagaa cttgttggag aagttttaag cgttataaaa
     8281 tctcttgcaa aagaaggtat aacgatgctt attgtaactc acgaaataaa ttttgcaaaa
     8341 gaagttgctg ataaaattat atttatggat aatggtgtaa tagctgaaga aggaactcct
     8401 gatgaaatat ttaataatcc taaaaatgaa agaacagcaa aatttttaaa tatcattagg
     8461 aaagaagaag tatttagtta aaagtgtata aattaagcat tagaagatat gtaagatacc
     8521 cccattaaat ttataagtta gataataaat ttaatggg
//
LOCUS       DAMKNB010000121         8496 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.127, whole genome shotgun sequence.
ACCESSION   DAMKNB010000121 DAMKNB010000000
VERSION     DAMKNB010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8496)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8496)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8496
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.127"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            267..1253
                     /locus_tag="PC494_003327"
     CDS             267..1253
                     /locus_tag="PC494_003327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HDF3913798.1"
                     /translation="MKKITINDIANLAGVSKSTVSRYLNNKDISDSTKEKIKTIIDEY
                     GYEPNAFAQSLRAKKTYFIGIITPCLDSFVKSKIMMAIDEELKKLKYTSLIINTNRKI
                     RSEIDSISKLASLKVDGIILIGTEITKEHKNEIEKLDIPIVVVGQKVDGINSIVNDDY
                     GAGYKMGQYIANKGYKNIVYLGVDESDISVGLNRKNGVLNGLKDKGYDAKVFYTDFDQ
                     EMSIQRSGEMLESENPDIIICATDNIAIATMKEINKRGKSIPQDISVAGFGGYDVLSI
                     ISPKLTTIKFENKNAGKVAANTIVNLIQERKEPLLKEIKFELIEGESTINKN"
     gene            1422..1570
                     /locus_tag="PC494_003328"
                     /pseudo
     CDS             1422..1570
                     /locus_tag="PC494_003328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423822.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIB"
     gene            1589..3070
                     /locus_tag="PC494_003329"
     CDS             1589..3070
                     /locus_tag="PC494_003329"
                     /EC_number="3.2.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose-6-phosphate hydrolase"
                     /protein_id="HDF3913799.1"
                     /translation="MYKEPKYRTILESTKEELNKLRNISLNDKYKPLFHIHPQHGLLN
                     DPNGLAYYNGKYHVFYQWYPYDATHGMKHWAYVSSDDFVNWNREDVALIPIESYESHG
                     AYSGNAIEVDGKLHMYYTGNIKYSAEDRYAYQNLAIMNKDGKITKYENNPIVSEIPKG
                     YTGHVRDPKVFKRKDKYFMLLGAQTSDKKGVIIVYESKNSIDWNFKGELNVKNIDEDF
                     GYMWECPDYINIDEKDILIFSPQGVEPKGFDYQNIYNVVYAIGNMDLDNLTFEIDTMK
                     ELEKGFDFYAPQTFIKDSQIILFAWAGMGEVLYPTDKNKWAHCLTVPRKLNIKNNKLL
                     QMPVDELIKLRYDETSGQNTIKNNINIIENDENVYELNINIKNIDSNKFGLELFSSQD
                     EGVKLEFNKLGNIVTLDRSNFKKVFGVEYGTNRKEYINIDENTNIKVLADRSILEIFI
                     NEGEVVFTSRIFAKENSNQIRVYSDKIVEYEYTKFKLKQGIEL"
     gene            3096..4067
                     /locus_tag="PC494_003330"
     CDS             3096..4067
                     /locus_tag="PC494_003330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate kinase"
                     /protein_id="HDF3913800.1"
                     /translation="MKKVISIGEALIDFIPNQNGGKLKNVSEFRRVAGGAPANVSAVV
                     AKLGGKSSFISKLGKDAFGDYIIDVLNEVNVNTDYVLRTSKANTGLAFVSLKEDGNRD
                     FSFYRNPSADMLLEADEVKKEWFNNCHILHFCSVDLIDSPMKLAHKKAIEYALESNSI
                     ISFDPNIRLPLWDSEQSCKKAISEFLPFAHIVKISDEELEFITGENDIEKSLHKLFVG
                     NVELVLYTKGKDGVDAYTKKVKGMCKGVKVNAIDTTGAGDSYIGSFLYTLLYKQITLN
                     DIKEMKQETLNEYLEFSNYYAARSTTIKGAISSYATKEEITEFIKNL"
     gene            complement(4323..4925)
                     /locus_tag="PC494_003331"
     CDS             complement(4323..4925)
                     /locus_tag="PC494_003331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HDF3913801.1"
                     /translation="MEVCILMGSPKKKGNTAAILKPFIEELENYNSNIEVIWLYDCKI
                     EPCIACKKCQDNLFDFGCYCKDDVQKIFKKILMCDLIVFATPIYSWYCTSPMKALLDR
                     LVYGMNKYYGNEKGPALWAGKSVALITTCGYRPEKGADIWENGMKRYCKHSQLKYIGM
                     LVERDLGKPNFMNKEKEEHSRQFAKQIYYILSNSIELDNC"
     gene            5206..6417
                     /locus_tag="PC494_003332"
     CDS             5206..6417
                     /locus_tag="PC494_003332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal-dependent decarboxylase"
                     /protein_id="HDF3913802.1"
                     /translation="MYSNEDYKFIEENAPCYIYDETNIIEKCKELKNNILGFDFLYSI
                     KTNPYNKIVKSIAEQGFGADASSTNEVMISSKCGVSKDDIYYSSPGKTEIDIETVLDK
                     CIIIADSITEIELINKISKKHNQKVKIGIRINPDFTMDDDSAKSSKFGIDIEDMSSVF
                     KMLSMCDYVSVVGIHIHIKSQVLDFEKLGHYYEKCFFIALNLNKSKYINIEFINFGSG
                     LGVAYDNLRENPLNLKELSKLTQKIAFTNSNTLKSRLLIESGRFIVCKSGNYYVKIVD
                     IKVSRGKKYLIVKNGLNGFMRPIISNLIENITCGVELEGQEPLYTSNHAFSLSVLNNL
                     KEEEYVNVVGNLCTSLDVIANNVKLKKANIGDLISISNAGSYSYSLSPLLFSSYEFPK
                     QYYKRKDGYIE"
     gene            6485..6682
                     /locus_tag="PC494_003333"
     CDS             6485..6682
                     /locus_tag="PC494_003333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug transporter"
                     /protein_id="HDF3913803.1"
                     /translation="MELWKRNLFVCWIGMFFSSIGMSQIAPILPLYIKQLGVTDVSLI
                     QQYSGIIFGCTFVVAAFFSPI"
     gene            6716..7687
                     /locus_tag="PC494_003334"
     CDS             6716..7687
                     /locus_tag="PC494_003334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDF3913804.1"
                     /translation="MLLRASIGMGIVIFTMAFVQNVYQLLGLRILQGVFTGYATACTT
                     LIATQTDKNHSGWALGTLATASTTGSLIGPTVGGYIESILGLKSTFIITGGLLFVSFI
                     ISILFVVDNFKPKEIKESISIPKEQLNILPNKFLIASIFVTTFITQLALYSIEPIVTI
                     YISQLTNFASNVALIAGLTFSASGLANLLAAQKLGKMSDKIGPQKVLLISLLWAGIIF
                     IPQAFVKTAWQLMLLRFLLGLSVAGLNPSVNSLLKKIAPEEYVGKIFGYNASAQYIGC
                     SSGAFLGGQISAHLGIRTVFFSTSLLLFRNALWMYKFTGLFIKDKTK"
     gene            7874..8251
                     /locus_tag="PC494_003335"
     CDS             7874..8251
                     /locus_tag="PC494_003335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HDF3913805.1"
                     /translation="MTISKIPQAELKVMKFIWEKNDTVTSKETIEAMERKYGWKQTTT
                     LTLLSRLVKKHFLSAEKIDRYTHYTIVVGHKEYLSVETKDFLSNIHDNSLQSLISALH
                     DDEVVDKDMLDLFESHFKNLEEE"
BASE COUNT         3457 a          885 c         1364 g         2790 t
ORIGIN      
        1 gctatggttg taaaaatcat agccttattt ttatattata aataaattag agtatttatc
       61 aattcatagt agataaaatt gaaattaaat ataacaacaa aaaatgaaaa ttacaattaa
      121 tttaatgtta aagactcaat tatttggatg tggaatggat agtacaagta gtatataaaa
      181 agtattgact ggacaaataa ctatatttta ttttaaatat ataatataat gtaataaaat
      241 atatcaaatg tagaaggtga taacctatga aaaaaataac aataaatgat attgctaact
      301 tggcaggagt atctaaaagt actgtatcaa gatatctaaa caataaagat atcagtgatt
      361 ctactaaaga gaaaataaag acaataatag atgaatatgg atatgagccg aatgcatttg
      421 ctcaaagttt gagagctaaa aaaacatatt ttattggtat tataacaccg tgtttagatt
      481 cttttgtaaa atctaaaatt atgatggcaa tagatgaaga actcaaaaaa ttaaaatata
      541 catcactaat tattaatact aatagaaaaa taaggtcaga aatagatagt atatcaaagt
      601 tagctagtct aaaagttgat ggaataatac taattggtac cgaaataact aaagaacata
      661 agaatgaaat tgaaaagtta gatataccga tagttgtagt tggacaaaaa gttgatggta
      721 tcaatagcat agtgaatgat gattatggag caggctataa aatgggtcaa tatattgcta
      781 ataaaggtta caaaaacatt gtatatttag gtgttgatga aagtgatata tcagttggtt
      841 taaatagaaa aaatggagta cttaatgggt taaaagataa agggtatgat gcaaaagtat
      901 tttatactga ctttgaccaa gaaatgtcta tacaaagaag tggagaaatg ctagaaagtg
      961 aaaatccaga tataataata tgtgcaactg ataatatagc aatagcaaca atgaaagaaa
     1021 tcaataagag aggtaaaagt ataccacaag atatatctgt agctggattt gggggatatg
     1081 atgtattgtc tattataagc cctaaactta caacaataaa gtttgaaaat aaaaatgcag
     1141 gtaaagtagc agcaaatacg atagtaaatt taatacaaga aagaaaagaa ccactattaa
     1201 aggagattaa atttgaatta atagaaggtg aaagtacaat aaataaaaat taagatacac
     1261 attacatata ttagtaatgt gtattttttt actaaaaaaa ctataattct aaaaattagg
     1321 aaaacttttt tgaaagaaat attgcatctg aaataaattt atgctaatct ttaattaaac
     1381 cggtttcgaa accggtttaa ttaaaccgat agaatagcaa aatgagtgca aaaataactg
     1441 attgtaacaa agtatcaaag taattattgg agtacatagg aataaacaaa atataaaaga
     1501 tgtagcacat tgtgtaataa gactaagaat tgttttagat agcaataata aagcaaatat
     1561 aaaattataa aagaaaagga ataaaaatat gtacaaagag cctaaatata gaaccatatt
     1621 agaatcgaca aaagaagaat taaataaatt aagaaatata tctttaaatg ataaatataa
     1681 accactattt catatacatc cacaacatgg actacttaat gacccaaatg gattagcata
     1741 ttataatggt aagtaccatg tattttatca atggtatcca tatgatgcaa ctcatggaat
     1801 gaagcattgg gcttatgtaa gttctgatga ttttgtaaac tggaatagag aagatgtagc
     1861 attaatacca atcgaaagtt atgaatctca tggagcatat tcaggtaatg cgatagaggt
     1921 agatggaaaa ttgcatatgt attatacagg gaatataaaa tatagtgcag aagatagata
     1981 tgcatatcaa aacttagcta taatgaacaa ggatggtaaa ataactaaat atgaaaataa
     2041 tccaatagta agtgaaatac caaaaggata tacaggacat gtaagagacc caaaagtatt
     2101 taaaagaaag gataaatact ttatgttact tggagcacaa acaagtgata aaaaaggagt
     2161 tataatagta tatgaatcta aaaactctat agattggaat tttaaaggag aattaaatgt
     2221 aaaaaacata gatgaagatt ttggttacat gtgggaatgt ccagattata ttaatataga
     2281 tgaaaaagat atattaatat tttcaccaca aggagtagaa cctaaaggat ttgattatca
     2341 aaatatatat aatgtagtat atgctattgg taatatggat ttagataatt taacatttga
     2401 aatagataca atgaaagaac tggaaaaagg atttgatttc tatgctccac aaacatttat
     2461 aaaggactca caaataatac tatttgcatg ggctggaatg ggagaagttt tataccctac
     2521 agataaaaac aaatgggcac attgtctaac tgttccaaga aaattaaata taaaaaataa
     2581 taagctattg caaatgccag tagatgaatt aattaaatta agatatgatg aaacaagtgg
     2641 gcaaaatact ataaagaata atattaatat tatagaaaat gatgaaaatg tatatgagct
     2701 taatattaat ataaaaaata ttgacagcaa taaatttggg ctggaattat tttcatcaca
     2761 agatgaaggt gtaaaattag aatttaacaa attaggaaac attgtaactt tagacagaag
     2821 caactttaaa aaagttttcg gtgttgaata tggaacaaat agaaaagaat atataaatat
     2881 tgatgaaaat actaatatca aagtactagc ggatagaagt attttagaaa tttttataaa
     2941 tgaaggagaa gtagtattta ctagtagaat atttgctaaa gaaaattcta atcaaataag
     3001 ggtttatagt gataaaatag tagagtatga gtatactaaa tttaaattaa agcaaggtat
     3061 tgaattataa aaacacatta taaggggtag aaaagatgaa aaaagtaatt agtataggag
     3121 aagctttaat agactttata cctaatcaaa atggtggtaa attaaaaaat gtatcagaat
     3181 ttagaagagt agcaggagga gctccagcaa atgttagtgc tgttgtagca aagcttggag
     3241 gaaaatcgag ttttatatct aagttaggaa aagatgcatt tggtgattat ataatagatg
     3301 tattaaatga agtaaatgta aatactgatt atgtattgag aacaagtaaa gcaaatacag
     3361 gacttgcttt tgtatcatta aaagaagatg gtaatcgtga tttctcattt tatagaaatc
     3421 caagtgcaga tatgctttta gaagctgatg aagttaaaaa agagtggttt aataattgtc
     3481 atatcctaca tttttgttca gtagatttaa tagatagtcc aatgaaatta gcacataaaa
     3541 aagcaataga atacgcactt gaaagtaata gtataataag ctttgaccct aatataagat
     3601 tacctttatg ggatagtgag caatcttgta aaaaggcaat atcagaattt ttaccttttg
     3661 ctcatattgt taagatatct gatgaagaat tagaatttat aacaggagaa aatgatatag
     3721 aaaaatcatt acataaactc tttgtgggga atgttgaact agtattatat acaaaaggaa
     3781 aagatggagt agatgcatac actaaaaaag taaaaggtat gtgtaaaggg gttaaagtaa
     3841 atgcaataga tacaaccgga gcaggagatt cttatatagg ttcattttta tacaccttat
     3901 tgtataaaca aataacattg aatgatataa aagaaatgaa acaagaaacg ttaaatgagt
     3961 atttagaatt ttctaattat tatgcagctc gtagtacaac tattaaaggt gcgataagtt
     4021 catatgcaac aaaggaagaa ataactgaat ttataaaaaa tttatagtag gaatgagtaa
     4081 taggttttga aggaagtaac atgtaaagag tttttaagga tgtttactat gaaaataatt
     4141 aacatataaa aagcaataag gaggctgtct caaaatagag ataagcctct ttatcattgt
     4201 tgaaatgata aaaaatattt taattattgt tactttttag aagaatatat atcttatttt
     4261 aaataagcaa attatgtaag atttatttat attatcaata ctttacttgg agtattatgt
     4321 ctttagcagt tatctaattc aattgaatta gataaaatat aataaatttg ttttgcaaat
     4381 tgacgagaat gttcttcttt ttctttattc ataaaattag gtttacctaa atcacgttca
     4441 acaagcattc ctatatattt taactgtgaa tgcttacagt agcgcttcat accattttcc
     4501 caaatatcag cacccttttc aggtctatat ccacatgttg taataagtgc tactgatttt
     4561 cctgcccata gagcggggcc tttctcatta ccatagtatt tattcattcc atacaccaat
     4621 ctgtcaagta gtgctttcat tggagaagtg cagtaccaag aataaattgg agtagcaaaa
     4681 acaattaaat cacacataag aattttcttg aaaattttct gaacatcatc tttacaataa
     4741 catccaaaat caaataagtt atcctgacac tttttacaag caatacatgg ctctatttta
     4801 caatcatata accatattac ttcaatattt gaattataat tttctaattc ctcaataaaa
     4861 ggttttaaaa tagcagcagt attacctttt ttcttaggac ttcccataag aatgcatact
     4921 tccatattga tacctccaca gtattttaaa atagttttta gtgcttaata tagttttagg
     4981 atactatgag aatacgttaa caacaataca ctttgtatat ttgtaataaa attgaaacaa
     5041 attgttttat caataaaagt tggaatgtat ctataattaa aaatatttta ggtatgtttt
     5101 tacatatatg tgtgtagtta actatggtaa tttattgtaa aattatctta taggattata
     5161 attgcttaat ttatgattat atttaaaatc ttggaggtaa aaaatatgta ctcaaatgaa
     5221 gactataaat ttatagaaga aaatgcacca tgttatatat atgatgagac taatataatt
     5281 gaaaaatgta aggaattgaa aaataatatt ttaggttttg attttttata ttctataaaa
     5341 acaaatccat ataacaaaat tgtaaaaagc attgcagagc aaggttttgg agcagatgct
     5401 tcttcaacta atgaagttat gatttcatca aaatgtggag tttctaaaga tgatatttat
     5461 tattcatcac caggcaaaac agagattgat atagaaactg ttttagataa atgcataatt
     5521 attgcagata gtattacaga aatagaactt ataaataaga tatctaaaaa gcataatcag
     5581 aaagttaaaa taggaataag aataaatcct gattttacta tggatgatga tagtgctaaa
     5641 tcaagcaaat ttggtataga tatagaagat atgagcagtg tttttaagat gttaagtatg
     5701 tgtgattatg tatctgtagt tgggattcat atacatatta aatctcaggt attggatttt
     5761 gaaaagttag gacattatta tgaaaaatgt ttttttatag ctttaaattt aaataaaagt
     5821 aagtatatta atattgaatt tataaatttt ggtagtggac ttggagtagc ttatgataat
     5881 cttagagaaa atccacttaa tcttaaagag ctttcaaaat taactcaaaa gattgctttt
     5941 actaattcaa acacactaaa atcaagactt cttattgaat caggacgttt catagtttgt
     6001 aaatcaggta attattatgt taaaattgta gatattaaag tatcaagagg gaaaaaatat
     6061 cttattgtaa aaaatggact taatggattt atgagaccta ttatttctaa tttaattgaa
     6121 aatattactt gtggagtaga attagaaggt caagagccat tatatacatc aaatcatgcc
     6181 ttttctcttt cagtattaaa taatttaaaa gaagaagagt atgtaaatgt tgttgggaat
     6241 ctctgtacat cattagatgt aattgcaaat aatgttaaat tgaaaaaagc aaacatagga
     6301 gatttgattt caattagtaa tgctggaagt tactcctatt ctttatcacc gctattattt
     6361 tcaagttatg aatttcctaa acaatattat aaaagaaaag atggatatat tgagtaaaca
     6421 atagcataaa ttaataaact tagtattatt gaaaaaattt aaaatgcagg gggtgtaatt
     6481 ctatatggaa ttgtggaaaa gaaatttatt tgtatgttgg ataggtatgt tttttagttc
     6541 tatagggatg agccaaatag cacctatact tccattatat attaaacagt tgggggtaac
     6601 tgatgttagt ttaatacaac agtattcagg tataattttt ggatgtacct ttgtagtagc
     6661 agcattcttt tcgccaattt gagggaaagc tgctgataaa tatggaagaa aatcaatgct
     6721 tttacgtgca agtattggga tgggaatagt tatatttacc atggcgtttg ttcaaaatgt
     6781 ttatcagtta ttaggattaa gaatacttca aggagttttt acgggttatg ctactgcatg
     6841 tactactctt attgcaacac agacagataa aaatcattca ggatgggctt tgggtactct
     6901 tgcaactgca tcaactactg gctcattaat tggtccaaca gtaggaggat atatagaatc
     6961 aatcttaggt cttaaaagta catttattat aacaggagga ttgttgtttg tatcatttat
     7021 catctctatt ttatttgtag tagataattt taaacctaaa gaaataaaag aatcaatttc
     7081 tatacctaaa gaacaattaa atatattgcc aaataaattt ttaattgcat ctatttttgt
     7141 aaccacattc attactcaac tagctttata ctctatagaa ccaattgtaa ccatatatat
     7201 atcacaactt acaaattttg catcaaatgt agctttaata gctggattga cattttctgc
     7261 atcaggatta gcaaatttat tagcagctca aaaacttgga aaaatgtcgg ataaaatagg
     7321 tcctcaaaaa gtattgttaa tttcactttt atgggctggg attatattta taccacaagc
     7381 ttttgtaaaa actgcatggc aactgatgtt gttgagattt ttattagggt tgtcagttgc
     7441 agggcttaat ccttctgtta acagcttgct taaaaaaatt gcaccagaag aatatgtggg
     7501 aaaaatattt ggatataatg catctgccca gtatataggc tgttcatcag gagcattttt
     7561 agggggacaa atatcagcac atttaggtat tagaacagta tttttttcaa caagtttatt
     7621 gttgtttagg aatgcacttt ggatgtataa atttactgga ttgtttatta aagataagac
     7681 taaataatca tactatttac atttctaatt ttatgatgta aaataaatat tttttatgta
     7741 atttatcata gaattatata aaaaataacc ctatggtaaa aattggaaaa tattattatc
     7801 gacaaaatct ttgacttaaa aactatattg cgatagtatt aatttaataa aagtttgaga
     7861 ggggcgtaag gttatgacaa tttcaaaaat accacaagca gaattaaaag ttatgaagtt
     7921 tatttgggaa aaaaatgata cagtaacatc aaaagaaact attgaagcta tggaacgaaa
     7981 atatggttgg aaacaaacaa ctacattgac acttttatca agacttgtta aaaaacattt
     8041 tttaagtgca gaaaaaatag atagatacac tcattataca atagttgttg gacataagga
     8101 gtatttaagt gttgagacaa aagatttttt aagcaatata cacgacaatt ctttacagag
     8161 tttaatttca gcactacatg atgatgaagt tgttgataaa gatatgttgg atttatttga
     8221 aagtcatttt aaaaatttag aagaagagta attatatcag gatagaactc taagaattta
     8281 attaatctat ggctgaaaac cataaatggt attatttaat cagctactca ctattcataa
     8341 agtaatatta aataggttct ctaattagta aaatgcctaa aataattgga atagggagta
     8401 tcaagttaaa tgataccact tatttaaata agaaatgatt tttaaaattt aaaataattt
     8461 tataacttgt caatattcat taatctaaag tattat
//
LOCUS       DAMKNB010000122         8424 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.128, whole genome shotgun sequence.
ACCESSION   DAMKNB010000122 DAMKNB010000000
VERSION     DAMKNB010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8424)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8424)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8424
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.128"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            complement(223..1092)
                     /locus_tag="PC494_003336"
     CDS             complement(223..1092)
                     /locus_tag="PC494_003336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HDF3913806.1"
                     /translation="MEYDMPLYRPPSEAYSLIIQVTLGCSHNKCTFCSMYKSKKFKIK
                     PLEVIKNEIDIFRRYYKHVERIFLADGDALIIPMEKLRDIILYIKEVFPECERITMYG
                     SPKSIEKKSDDELKELRKLGVKMIYLGLESGSNEVLEDIKKGFSSEQLIKVGRKVKKS
                     GIKLSATVIAGLGGTKKTHQHAVDTGKMLGAISPDYVGVLSLMVEPNTELYDLLKAGE
                     FTILEDKAVLQEIKEMIKNIDANEKIVFRSNHASNYANLKGVLPDDKQRLIDEIDYYL
                     SNQKLKREEYRRL"
     gene            complement(1189..2046)
                     /locus_tag="PC494_003337"
     CDS             complement(1189..2046)
                     /locus_tag="PC494_003337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDF3913807.1"
                     /translation="MSKDVKVKRNKKYDTFSITMELERPLLYDEVENKDDKNNNRKFN
                     IKNKIFKGIGILFVLILLGFFIWINKTYEPQKLAKEALVSNSKVEVTVNENISFTPKG
                     RKVSKGLILYPGAKVEIESYAPLARKIAESGYEVVIVKMPLNLAILGTNKAQKVMDSY
                     NNIEHWVIGGHSLGGVAASNFARDNKLIEGVVFLASYPMGDELKELGKKVISIWGSKD
                     GVVNFKSLVESKQKLPDDTTYVEIEGGNHAQFGDYGKQKGDNDAIISQEKQLNITANS
                     IIKFLKNIS"
     gene            complement(2260..4278)
                     /locus_tag="PC494_003338"
     CDS             complement(2260..4278)
                     /locus_tag="PC494_003338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HDF3913808.1"
                     /translation="MTKKLVISKTKLFIFIIAFISIFIYLFGSKNTLIGVGIVTAMLT
                     LLERDLTISPIKNLLKYLAINIILGILSFFAVQNMYLGVLLNFIALFIIGYVFSYDLK
                     RAVYVPFGLMYIFMVSIPVGKSEFPMRLSALAVGAVIIMIAQFVMNRNRMKNVGDKEL
                     ISICDELLEKISLLKNTINDDSSIIKSSMRKIDSCNYRINSISKNLKMVIFDNRKDDF
                     YISIRGIDIMNILFSLERISLILERYKKDSKEFEDEDIKNILEESSINSKSDVLVVAT
                     KEINYIKMCLENKDTITDKEILGFRDYVISQDTKNINLKEIYSVLENLYEFLVDYKKV
                     KSRDEKKAERKSKIPHEFKRLSIYKKNFNLNSIRFSYAVKIALATAVAGFIMDYFHLR
                     DGRWIMLTVFSLTQPYAENCIQRSRKRIEGTFIGAVIFIVLFSIIKDSTLRSLIVLLA
                     GYINSYVVDYRKLMVCVTVSALGSAVVMGDPNVLTISRISYVALGAIIALIVNKFILP
                     YDAKTGYQHVIEMYKGIVKNIIDEVNKSIENVADVYYIKNLLLIPSLIEDRLMLINAI
                     YKDKHQEDFLENQKLLISNMYNLYINVNKNKIKDEDVEKILRDTNYISNYNVDKYDEG
                     RSVILESIVNTKSLGDKIICLNLLQTLNGVKEMYRISNITKVSIKEAA"
     gene            complement(4549..5325)
                     /locus_tag="PC494_003339"
     CDS             complement(4549..5325)
                     /locus_tag="PC494_003339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HDF3913809.1"
                     /translation="MHKETLDKLTNAAINKINLLNTSKVKYLVSSAFAGLYVGIGILL
                     IFTIGGLLTDAGSPMTKIVMGLSFAIALSLVIMTGTELFTGNNMVMSAGMLNKGVSIK
                     DTSKIWAYSWVGNLIGALVLGIIFVGTGLVDKGPVAEFFANTAASKASMPFTALFFRG
                     ILCNILVCVSVLCSFRTNSDTAKIIMIFLCLFAFITSGFEHSVANMTIYSVSLFSPTI
                     STVTIGGAIYNLVAVTLGNIVGGALFMGLGTYILGKEKLN"
     gene            complement(5382..6353)
                     /gene="asrC"
                     /locus_tag="PC494_003340"
     CDS             complement(5382..6353)
                     /gene="asrC"
                     /locus_tag="PC494_003340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite reductase subunit C"
                     /protein_id="HDF3913810.1"
                     /translation="MIRDLNTKKVMKNAYRITKTKYETSLRVRVPGGLIDPESLAVVS
                     KIASEYGNGQVHITTRQGFEILGINMEDMEEINKIIQPVIEKMNINQSEKNAGYPAAG
                     TRNIAACIGNKVCPKAQYNTTEFAKRIEKAIFPNDLHFKVALTGCPNDCIKARMNDFG
                     IIGMALPIYEKDRCVNCGACVKKCSKISVGALKTENNKVVRDKDKCIGCGECVLNCPT
                     NAWTRDEKKYYRLAIMGRTGKKNPRLAEDFLLWVDEDSIIKIILNTYRYVEKYIDKDA
                     PGGKEHIGYIIDRTGFMEFKKWALEGVELPEITKMYENIYWSGIKYL"
     gene            complement(6366..7157)
                     /gene="asrB"
                     /locus_tag="PC494_003341"
     CDS             complement(6366..7157)
                     /gene="asrB"
                     /locus_tag="PC494_003341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic sulfite reductase subunit AsrB"
                     /protein_id="HDF3913811.1"
                     /translation="MNPYIPVSAKILDIVKHTDKEWTFRVNCNTKGVLPGKFYEISIP
                     KYGESPISVSGYGEDYIDFTIRNVGKVTSELFNYKEGDSFFIRGPYGNGFDVSLYEGR
                     EIVVVAGGSALAPVRGIVEYFYNNKEKCEKFKLIVGFKSPKDILFADDLKRWSKKLDI
                     LVTVDGAEEGYSGNVGLVTKYIPELDMKDINNTSIVVVGPPMMMKFTVEEFLKRDLDE
                     KNIWVSYERKMCCGIGKCGHCKMDDTYICLDGPVFDYSYAKNLID"
     gene            complement(7158..8165)
                     /gene="asrA"
                     /locus_tag="PC494_003342"
     CDS             complement(7158..8165)
                     /gene="asrA"
                     /locus_tag="PC494_003342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic sulfite reductase subunit AsrA"
                     /protein_id="HDF3913812.1"
                     /translation="MKLKLDSSKFNEGLNYLKKDYKIFAPVLIPFKGTFSDTDVIRYK
                     EVNAFEEMEFAKKANFSPKEVVLPINQVLFYFTEKEFKESDLDNKKILIFLRACDING
                     IKRLDEIYLNNGEEKDYFYKNIRDKVKFALVGCKESFRNCFCVSMDSNKTDNYSIGLN
                     IEGDTLYLDIKDSEFEVFNGEATEFNVDYVTDNLISVDVPENIDSNEMIGNSIWDEYD
                     TRCIGCGRCNFVCPTCSCFTMQDIFYKENENVGERRRVWASCQVDGYTDIAGGNSFRK
                     KQGERMRFKTMHKIHDFKKRFGYHMCVGCGRCDDACPQYISFSKCIEKINDLVISKEE
                     V"
BASE COUNT         2717 a         1518 c          755 g         3434 t
ORIGIN      
        1 ctttttatta tttaaattcc tgtttttatt ataataggta aaattctatt aaactagttc
       61 acattttcat tattattgat atattatata tgaatatacc attttgtttt ttaataaaaa
      121 aatcatgcta catcaatagt aagcaactat taatgtagca tgattttttg tatctaaata
      181 atcttagtat ttacctatca atatagattg atatatcaaa aactatagtc ttctatattc
      241 ttctcttttt agcttttggt tacttagata gtaatcaatt tcatcaatta gacgttgttt
      301 atcatcaggt aatacacctt ttaaattagc ataatttgat gcatgattac ttctaaatac
      361 aattttttca ttagcatcta tattctttat catctcttta atttcttgta acacagcctt
      421 atcctctagt attgtaaact ctcctgcctt aagtaaatcg taaagttcag tattaggttc
      481 taccattaaa ctaagtacac ccacataatc tggtgaaatt gctcctaaca tttttcctgt
      541 atcaactgca tgctgatgtg tttttttagt tcctccaaga cctgctatta cagtggctga
      601 taatttaatc ccactttttt taacttttct accaactttt attaattgtt cactactaaa
      661 acctttctta atatcttcta atacttcatt gcttccactt tcaagcccta gataaatcat
      721 tttaacacca agttttctta attctttaag ttcatcatca gattttttct ctatagattt
      781 aggagagccg tacatagtaa ttctttcaca ctctggaaaa acttctttta tatataaaat
      841 aatatctctt aatttctcca ttggtattat caatgcatct ccatctgcta agaatattct
      901 ttctacatgc ttataatatc ttctaaatat atcaatttca ttttttatta cttctagtgg
      961 ctttatttta aattttttag atttgtacat actacaaaac gtacatttgt tatgagaaca
     1021 tcctagtgtg acttgtatta taagactata agcctcactt ggtggtctgt aaagtggcat
     1081 atcgtattcc atattaaaat cccccttgta ataaaatatt cattctatta tattattaat
     1141 atttacttta aataataact tataaaatta tattttttaa attttagttt aagatatatt
     1201 ctttaaaaat ttaatgatac tattggcagt aatattaagt tgtttttctt gacttataat
     1261 agcatcatta tctccctttt gttttccata atctccaaat tgtgcatgat ttcctccttc
     1321 aatctcaaca taagttgtat catcaggaag tttttgtttt gattctacaa gacttttaaa
     1381 attgactact ccatctttgc tcccccatat agatataact ttttttccta attctttcaa
     1441 ctcatcaccc attggataag aagctaaaaa tacaacgcct tcaattaatt tattatcacg
     1501 tgcaaaattt gatgctgcaa ctcctcctaa tgaatgacct cctattaccc aatgttctat
     1561 gttgttgtaa gaatccataa ctttctgtgc cttattagtt ccaagtatag ctagattaag
     1621 tggcatcttt acgattacaa cctcatatcc actttctgct atttttcttg caagtggagc
     1681 ataagattct atttctactt tagctcctgg atacaaaatt aaacctttag aaacttttct
     1741 tccttttggt gtaaatgaaa tgttttcatt tacagttact tcaactttac tattgctgac
     1801 tagagcttct tttgccagct tttgaggttc atatgtttta tttatccata tgaaaaagcc
     1861 aagcaaaatc aatacaaata gtatacctat tcccttaaat atcttattct ttatgttaaa
     1921 ttttctatta ttatttttat catctttgtt ctcaacctca tcataaagta aaggtctctc
     1981 aagttccata gttatactaa atgtatcata tttcttatta cgctttacct ttacatcttt
     2041 actcataaat ctaaccccca taatatttga atactattat agtttatcct aagtaaattg
     2101 ttttttcaac caatgaaaaa aatcaatatt ttaactattt tcatataaaa ttcataaata
     2161 tatgtttttg ttttttatat attattttct tttagtattt tataaaacaa atagccatat
     2221 actttatttt aaatatatgg ctattctata atttaatatc taagctgctt cttttattga
     2281 aactttagtt atattactta ttctatacat ttctttgaca ccatttagag tttgcagtaa
     2341 gtttagacat attatcttgt cacctagact tttagtattt acaatactct ctaaaattac
     2401 acttcttcct tcatcatact tatctacatt gtaatttgaa atataattgg tatctctcaa
     2461 tattttttca acatcttcat cttttatttt atttttatta acatttatat atagattata
     2521 catattactt attagtaatt tctgattttc taaaaaatcc tcttgatgtt tatctttata
     2581 tatagcattt atcaacataa gtctatcttc aataagtgat ggtatcaata ataaattttt
     2641 tatatagtaa acatcagcta cattttctat agacttattg acttcatcaa ttatattttt
     2701 aactattcct ttatacattt ctataacatg ttgatagcct gttttagcat catatggtaa
     2761 tataaactta tttactatta atgcaataat tgctcctaat gctacatatg aaatcctgct
     2821 tattgttaaa acatttgggt ctcccataac tactgctgaa ccaagagctg aaacagttac
     2881 acataccatt aattttctat aatcaactac ataagagttt atataccctg ctaaaagaac
     2941 tattaacgac cttaatgtac tatcttttat tattgaaaat aatacaataa atattacagc
     3001 tcctataaat gtaccttcta ttctttttct agacctttgt atacaatttt ctgcgtaagg
     3061 ttgtgttaat gaaaagacag ttaacattat ccatcttcca tctcttaaat ggaaataatc
     3121 cataataaaa cccgctacag ctgtagctaa agcaatcttt actgcataag aaaatcttat
     3181 agaatttaaa ttaaagtttt tcttatatat tgatagtcgt ttaaattcat gaggtatctt
     3241 tgattttctt tcagctttct tttcgtctct tgattttact tttttataat ctactaaaaa
     3301 ctcatataaa ttttctaaaa cactataaat ttcttttaaa tttatatttt tagtatcctg
     3361 agaaataaca taatctctaa atcctaatat ctctttatca gttatggtat ctttattttc
     3421 taaacacatc ttaatatagt ttatttcttt cgttgctaca actaaaacat ctgatttact
     3481 atttatgcta ctttcttcta aaatattttt tatatcttca tcttcaaatt ctttactatc
     3541 ctttttgtat ctttccagga ttaaacttat tctttctaat gaaaataaaa tattcattat
     3601 gtctatacct ctaatactga tataaaagtc atcttttcta ttatcaaaaa taaccatttt
     3661 caaattttta gatatagaat ttattctata attacagcta tctatttttc tcatactaga
     3721 tttaattata gaactatcat cattaatagt attttttaaa agactaattt tttctaataa
     3781 ttcatcacat atagatatca gttctttatc tccgacattt ttcatcctat ttctattcat
     3841 aacaaattga gcaatcatta ttataactgc tccaacagct aaagccgaca atctcatagg
     3901 aaattcactt tttcctacag gtatacttac cataaatata tacattagac caaagggtac
     3961 atatactgct ctttttaagt cataactaaa tacataccct attataaata atgctataaa
     4021 atttaataaa actcctaaat acatattttg tactgcaaaa aatgatagta ttcctaagat
     4081 tatatttatt gctaaatact tcagtaaatt tttaattgga gaaatagtta aatctctttc
     4141 caagagtgtt agcatagctg ttactatacc tacacctata agtgtatttt tacttccaaa
     4201 taaatatata aatatagaaa taaatgctat tataaaaata aacaactttg tttttgatat
     4261 tactagtttc tttgtcatca tatcccccct aaaaatttca acaagaccaa ttttatcata
     4321 tttgttatct tattcaaaat gcgctttttt acggtaggac tttaactttt tttatattta
     4381 gaactatata attcatatat aaacgtattt tttatatata taaccgatat attttcgtat
     4441 gctcccatat tttttttgtt tcaaatattt tttcaaaaat ataaaaataa ctctctcaac
     4501 aatactaaaa atgtatttat caagagagtt ataatttata caataaattt aattaagctt
     4561 ttctttacct aatatataag ttccaagacc cataaataaa gctcctccaa caatatttcc
     4621 aagtgttaca gctactaaat tataaatagc tcctccaata gtaactgtac ttattgttgg
     4681 tgaaaataat gaaacactat aaattgtcat atttgctaca ctatgctcaa aacctgatgt
     4741 tataaaagca aataaacata agaatatcat aattattttt gcagtatcac tattagttct
     4801 aaacgaacac aacactgata cacatactag aatattacat aaaatccctc taaagaaaag
     4861 agctgtaaat ggcatggatg ctttactagc tgctgtattt gcaaaaaatt cagctacagg
     4921 tcctttgtct actagaccag ttcctacaaa tataatgcct aaaaccaaag ctccgattaa
     4981 attacctacc caactgtatg cccatatttt agaagtatct tttatactta cacctttatt
     5041 taacatacca gcagacataa ccatattgtt tccagtaaat aactctgttc ccgtcattat
     5101 aaccaaactt agtgctattg caaatgataa ccccattact atcttagtca taggtgaacc
     5161 tgcatcagtc aaaagtcctc caatagtaaa tatcaaaagt atacctatac ctacataaag
     5221 tcctgcaaac gcagaagata ccaaatattt tactttactt gtgtttaata aatttatctt
     5281 atttatagct gcattagtta atttatccaa agtttcttta tgcataactc cctcttcctt
     5341 ctattaaatt ttaatttatt caaatatatg ttttactcaa tttatagata tttaattcca
     5401 ctccagtata tgttttcgta cattttagtt atttctggaa gctctacacc ttcaagtgcc
     5461 cattttttaa attccataaa tcctgttcta tcaattatat atcctatatg ttcttttcct
     5521 cctggtgcat ctttatctat atacttttct acatatctat aagtattaag tattatcttt
     5581 attatgctgt cctcatctac ccataaaaga aaatcttctg ctagtctagg gtttttcttt
     5641 cctgttctac ccattatagc taatctatag tattttttct catctctagt ccatgcattt
     5701 gttgggcaat ttagtacaca ctctccacag cctatacact tatctttatc tcttaccacc
     5761 ttattatttt ctgtttttaa tgctccaaca gatatcttag aacatttttt tacacatgct
     5821 ccacaattta cacatctatc cttttcatat attggtaaag ccataccaat aattccaaag
     5881 tcattcattc tagcttttat acaatcattt ggacaaccag ttaaagccac tttaaaatgt
     5941 aaatcatttg gaaatatagc tttttctatt cttttagcaa attcagttgt attatattga
     6001 gcctttggac agactttatt tcctatacaa gctgctatat ttcttgtacc tgctgctgga
     6061 taacctgcgt ttttctcact ttgatttata ttcatttttt caataacagg ttgtataatt
     6121 ttatttattt cttccatatc ttccatattt attcctaata tttcaaaccc ctgtcttgta
     6181 gttatgtgca cctgtccatt gccgtactca cttgcaattt tagaaactac agctaaactc
     6241 tcagggtcaa taagacctcc aggtactcta actcttaaag aagtctcata ttttgttttt
     6301 gtaattctat aagcattttt cattactttt ttggtattta aatctcttat cacaaacttc
     6361 accccctaat caataagatt tttagcatat gaataatcaa atactggtcc atctaaacat
     6421 atgtaagtat catccatttt acaatgtcca catttaccta ttccacaaca catttttctt
     6481 tcataagaaa cccaaatgtt cttttcatct aaatctcttt ttaaaaattc ttctactgta
     6541 aatttcatca tcattggagg tccaactaca actatagaag tattgtttat atctttcata
     6601 tccaattctg gtatgtattt tgttactaat cctacattac cactatatcc ttcctctgct
     6661 ccatctacag taactaaaat atcaagtttt ttactccatc tctttaaatc atctgcaaat
     6721 aaaatatctt ttggtgattt aaatcctact attaatttaa acttttcgca tttttcttta
     6781 ttattataaa aatattcaac tattcctctt acaggggcta atgcacttcc tcctgccact
     6841 actacaattt ctcttccttc ataaagggat acatcaaatc catttccata aggacctctt
     6901 ataaaaaaag aatctccttc tttataatta aacaactcgc tagttacttt tcctacattt
     6961 cttattgtaa agtcaatata atcctctcca tatcctgata ctgatattgg actttcaccg
     7021 tatttaggta tagatatctc ataaaacttt ccaggcaata caccttttgt attgcagttt
     7081 actctaaaag tccattcttt atcagtatgt ttaactatat ctagtatttt tgcacttact
     7141 ggtatatatg ggttcattta tacttcctcc ttactaatta ctaaatcatt tattttttct
     7201 atacactttg aaaatgatat gtattgcgga caggcatcat cacatcttcc acaaccaaca
     7261 cacatatgat atccgaatct ttttttaaaa tcatgtattt tatgcatagt tttaaatctc
     7321 attctttcac cttgtttttt tctaaaagaa tttccacctg ctatatctgt atatccatct
     7381 acttgacaag aagcccaaac ccttcttctc tcacctacat tttcgttttc cttatagaaa
     7441 atatcctgca ttgtaaaaca tgaacatgtt ggacatacaa aattacatct accacatcct
     7501 atacatcttg tatcatattc atcccatatt gaatttccta tcatttcatt tgaatcaata
     7561 ttctctggca catctacaga tattaaatta tcagttacat aatcaacatt aaattcagtt
     7621 gcttctccat taaatacttc aaattcacta tcctttatat ctaagtacag tgtatctcct
     7681 tctatattta atccaattga ataattatca gttttgttag aatccatgct cacacaaaaa
     7741 cagtttctaa aactttcctt acaccctaca agtgcaaact ttactttatc tctgatattt
     7801 ttataaaaat aatctttttc ttcaccatta tttagatata tttcatcaag tctttttata
     7861 ccatttatgt cacaagctct taagaaaatt aaaattttct tgttgtctaa atcgctttcc
     7921 ttaaactctt tttcagtaaa ataaaacaat acttgattta tgggaagtac aacttctttt
     7981 ggtgaaaagt ttgctttctt agcaaattcc atttcttcaa aagcgtttac ctccttgtat
     8041 cttataacat cagtatctga aaaagtacct ttaaatggga ttaaaactgg tgcaaatatc
     8101 ttgtagtctt tttttagata attcagacct tcattgaact tagatgaatc taattttagt
     8161 ttcattttta tcacctttct tatattttag ttttacttac ttgctatctt gtttaaatct
     8221 taacacttta ttttctatgc ttccgtgata attatcacag tttcaaaaat aataaaaaaa
     8281 atattaatgg agtttattaa gttctgttaa tattttttta ttatctacat tattcaattt
     8341 caaatctaat cacttaaata caatcattaa gtacaataaa actactatct actcaatttt
     8401 ttgaataaaa aagaatctta tttg
//
LOCUS       DAMKNB010000123         8209 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.129, whole genome shotgun sequence.
ACCESSION   DAMKNB010000123 DAMKNB010000000
VERSION     DAMKNB010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8209)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8209)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8209
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.129"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            84..1526
                     /locus_tag="PC494_003343"
     CDS             84..1526
                     /locus_tag="PC494_003343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding repeat-containing protein"
                     /protein_id="HDF3913813.1"
                     /translation="MRTIRRVLALGLTLAIFLINVPNVDALTSDTIKGNNIYETAGLI
                     ADKKSYDTAIMVNMDNSIADGLSASGLAGAVDAPILLAQKNKIPNETKQRLKNVKKIY
                     IIGKELSISKSVETELKNTGAQVTRLGGDDRIKTSYSVAKEVNGIKKVDEVILTNAYK
                     GEADTISAAPVSVRDIAPIVLTDGKSVPFSTSNVKTYAVGGSISMSTSLVNKTNAKRL
                     GGSDRYDTNKKVIKEFYPDASEFYLSDGYDLVNALTGSTIAKENPIVLVSESSDKSIL
                     AGADKITRLGSISDSVYNKCVSAAQNNGDSSTKGESPMKNETSILGQPTASLEACLKW
                     AKSKKANDLFIELIPILYDTAVQEGVNPVLAVAQSAKETGFCNFGGVLDASFKNPCGL
                     KTSVGGSDTDKNAHSRFDTWEEGILAQIQHLCLYAGQDGYPLSNPVDPRHEKSLFGKA
                     KTVESLSNNWAGGQYGQDLVRMMGEIEATK"
     gene            1568..1921
                     /locus_tag="PC494_003344"
     CDS             1568..1921
                     /locus_tag="PC494_003344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3913814.1"
                     /translation="MKKSNIFSIIFPTVIMVLMFLTFATDIFNIPDIQSKSIFVVGMV
                     LIFPISFLIQGIICVLNKTNWILSLIVSLVTYIVLMYIFLNDSAYIYVLLYTAFYMIG
                     HITAKLYYKIKTFKN"
     gene            2112..2933
                     /locus_tag="PC494_003345"
     CDS             2112..2933
                     /locus_tag="PC494_003345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphatase HisJ family protein"
                     /protein_id="HDF3913815.1"
                     /translation="MNLIDNHIHTNFSSDGKDSMEDTIKKAISIGVRYLTFTDHLEHD
                     EDRGFCINYNDYVPVFNKFKEKYKKDIELLLGVEVGYRKHLKNEIEEIINSNPFDFVL
                     CSTHTIDNVPVPSKEYFKGLSKEDAYYKYFNSILETNREFGDYNIYGHLDYISRYGIY
                     SDNRVIYNDFKDVIDEVLKSIINNGSGIELNTSGYRYGLNAIHPNEDILKRYKELGGF
                     IVTVGSDSHRVEDICKDFDVAYDMLKYLDFKYVSLFKERETYFVNIEKVKSNNIA"
     gene            3191..5074
                     /locus_tag="PC494_003346"
     CDS             3191..5074
                     /locus_tag="PC494_003346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glycosidase"
                     /protein_id="HDF3913816.1"
                     /translation="MSNKNKENITLSNQIKGTIQNSLTKEAILHIPMSNYAYGYDRET
                     LHIRLRTKKNEAKRVILRIGDQYVWDKGGAGGGNLNASGVGWSGGTNIVMSKEVETEL
                     FDYWIAKCKPLNKRSRYGFIIEGQEEKLLFTEKRIIELGNENDEKELCEIGNFFGYPY
                     LNYIDIPKVPNWVKDTVWYQIFPDRFANGDPSINPEGVDKWGAIPTRDNFTGGDLQGV
                     IEHLDYLSDLGINGIYFCPITIGKTNHRYDTVDYMEVDPTLGDKETLKKLIEEAHKRN
                     IRIMLDAVFNHIGYYSKQWQDVVQNKENSRYKNWFYIKDMSKIDTPIEQIDEKNIPYE
                     TFGCEKYMPKLNTENSEVIKYLLDVGKYWIQEFDIDAWRLDVSNEVDHVFWRKFREEV
                     KKVKPDIYILGEIWHGSLPWLMGDQFDSVMNYLMSEAMKKFFCTDEINAEEFKYMIND
                     VMVSYPIQVSEVIFNLLGSHDTTRILTYANGNIDRFKLAYMFMFVQTGCPCIYYGDEI
                     GMEGELSSISEGQRKCMKWNEEKWNKDIFDFMKKIIRLRKENKELRSISNEWVLADKE
                     NGTIILKKESISIIINNSSKNIILTLPDYLANKKVKDLYEEEIVDLKEELMLEKYKFI
                     ILK"
     gene            5299..5979
                     /gene="pgmB"
                     /locus_tag="PC494_003347"
     CDS             5299..5979
                     /gene="pgmB"
                     /locus_tag="PC494_003347"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HDF3913817.1"
                     /translation="MIEAFIFDLDGVITDTAYYHYMAWRKLAHKVGIDIDTKFNESLK
                     GISRMESLDRILEFGNKKYSFSEEEKVRMAEEKNNYYVSLIDEITSNDILPGIESLLI
                     DVKSNNIKIGLSSASKNAINVLNHLGISDKFDFIADAGKCKNNKPHPEIFLMSAKGLN
                     VNPQNCIGIEDASAGIDAINSANMFSVGVGNYENLKKANLVVDSTNQLKFEYIQEKYN
                     EYIVRRII"
     gene            5976..>8209
                     /locus_tag="PC494_003348"
     CDS             5976..>8209
                     /locus_tag="PC494_003348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HDF3913818.1"
                     /translation="MKCLFSNVDEWKIIQDKIEIKENRLAESIMSIGNGYMGMRGNYE
                     ENYSGDTHKGSYIAGVWFPDKTRVGWWKNGYPEYFGKIPNSVNYIGVRIFIDDVELDL
                     AKCKVEDFYRELDMKNGILNRRFIVNINDKKFEVRVARFLSISVKELAVIKYSIKSLN
                     SNTKIKFVPYLDSNIKNEDSNYEEKFWNGISSSSLEYKGSILSRTKENAFNTPVFTVG
                     SMMYIKTNGDVEAISHESDYNYCENSITMDVLKNEVASIEKYVSITSTRDYKESELLR
                     KCEDILNRELSKSYDDILNEHTKLWNKRWESADVKINGDKSSQQGIRYNLFQLFSTYY
                     GEDSRLNIGPKGFTGEKYGGATYWDTEAFCVPVYLGVADKEVTRNLLEYRYNQLEQAK
                     DNAKKLGLKGALYPMVTFDGVECHNEWEITFEEIHRNGSIVYAIYNYTNYTGDYKYIK
                     EKGIDVIIEIARFWASRVHLSTKKDLYMIHGVTGPNEYENNINNNWYTNYIAKWCLDY
                     AVENILRLEKECNECIDRNNVTREEVEFWKIISNKMYLPYDEELQIIIQNDNFLDKEF
                     VEVKDLPKENFPLNQNWSWDKILRSCFIKQADVLQGIYYFGNRFTKEEKKRNFDFYEK
                     YTVHESSLSSSIYSIIASEIDNLEKAYELYSRTARLDLDNYNNDTNDGLHITSMSGSW
                     LSIVHGFAGMRTWNETLSFDPKLPKEWKNYSFNINYRDNIINVDVCSDLIKIENLKGR
                     PIKI"
BASE COUNT         3304 a          773 c         1512 g         2620 t
ORIGIN      
        1 ttataataaa tgactatagc gtagatgtaa tactatgtta tagtcatttt tgaattaaac
       61 ttgatatatc aagggggaag aatatgagaa caattagaag agttttagca ttaggtttaa
      121 cattagctat atttctaata aatgtaccta atgtagatgc attaacatca gatacaatta
      181 aaggtaacaa tatatatgag acggctggat taatagcaga taaaaagagt tatgatacag
      241 caattatggt aaatatggat aattctatag cagatggtct ttcagcaagt ggtcttgcag
      301 gtgctgttga tgctccaatt ttgcttgcac aaaaaaataa gataccaaat gaaacaaaac
      361 aaagattaaa aaatgttaaa aagatataca taataggtaa agaattatca ataagtaagt
      421 cagtagaaac tgaactaaaa aacacagggg cacaggtaac tagattaggt ggagatgaca
      481 gaataaagac tagttatagt gttgctaaag aggtaaatgg tatcaaaaaa gttgatgaag
      541 tgatattaac taatgcatat aaaggagaag cagatacaat aagtgctgca cctgtatcag
      601 taagagatat agctcctata gtacttacag atggaaagag tgtgcctttt tcaacaagca
      661 atgtaaaaac atatgcagta ggtgggagta tatcaatgag cactagttta gttaataaaa
      721 ctaatgctaa aagacttggt ggttcagata gatatgatac aaataagaaa gttataaaag
      781 agttttatcc agatgcatca gaattttatt tgagtgatgg atatgattta gtaaatgcac
      841 ttacaggttc tacaattgct aaggaaaatc caattgtatt ggtgtcagaa agtagtgata
      901 agtctatatt agcaggagca gataagatta ctagattagg ttcaataagt gacagtgtgt
      961 ataataagtg tgtttctgct gcacaaaata atggcgattc gtctacaaaa ggtgagtcac
     1021 ctatgaaaaa tgagacaagc atattaggtc agccaacagc tagtttagaa gcgtgcttaa
     1081 aatgggcaaa atctaaaaaa gctaatgatt tatttataga gttaatacca atattatatg
     1141 atactgctgt tcaggaaggt gttaatcctg ttttggcagt agctcaatct gcaaaagaaa
     1201 ctggtttttg taattttggt ggagtattag atgcatcatt taagaatcct tgtggactta
     1261 aaacttctgt aggtggttct gatactgata agaatgccca ttcaagattt gatacttggg
     1321 aagaaggaat attagctcaa attcaacatt tatgcttata tgcaggacaa gatggttacc
     1381 cactttcaaa tccagtagac cctagacatg aaaaatcttt atttggtaag gctaaaacag
     1441 ttgaaagttt atctaataat tgggctggag gtcaatatgg acaagattta gtaagaatga
     1501 tgggagaaat tgaggcaaca aaataattga agattatcaa atatccaata aataaggatt
     1561 gattattatg aaaaagagta atatttttag tatcatattt cctacagtca taatggtgct
     1621 aatgttttta acttttgcta cagatatatt taatattcca gatattcaat ctaaaagtat
     1681 ttttgttgtg ggaatggttt tgatttttcc aatctctttt ttgatacaag ggataatttg
     1741 tgtattaaat aagactaatt ggattttatc tcttattgtg tctttagtaa cttatatagt
     1801 attaatgtat atatttttaa atgattctgc atatatatat gttttacttt atacagcttt
     1861 ttatatgatt ggacatataa cagctaaact ctattacaaa attaagactt ttaaaaatta
     1921 aattgaagta tataaaagta acattaagag aagtatcctt aatgattttc taaaatcaga
     1981 aataggtgct tctctttttt gtaaaaataa aagtatgtaa ataaaattta accattataa
     2041 ttttctttta acaaatgtat acaataaact tgttgtataa ttaagataga taaaataaag
     2101 ggagggataa tatgaattta atagataatc atattcatac taatttttca agtgatggaa
     2161 aggattccat ggaagataca ataaaaaaag ctataagtat tggtgttaga tatttgactt
     2221 ttacagacca tttagaacat gatgaagata gaggattttg cataaattat aatgactatg
     2281 ttccagtatt taataagttt aaagaaaaat ataaaaagga catagagtta ttactaggtg
     2341 ttgaagtggg ttacagaaaa catctaaaaa atgaaataga agaaataata aattctaatc
     2401 cttttgattt tgtattgtgc tcaactcata caattgacaa tgtacctgtt ccatcaaagg
     2461 agtattttaa aggtcttagc aaagaagatg cgtattataa atattttaat agcatacttg
     2521 aaactaatcg tgaatttgga gattacaata tatatggtca tttggattat atatctaggt
     2581 atggaatata ttcagataat agagttatat acaatgactt taaagatgtt attgatgagg
     2641 tcttaaagtc aataatcaat aatgggagtg gtatagagct aaatacttct ggttatagat
     2701 atggactaaa tgctatacat ccaaatgaag atattctaaa aagatataaa gaacttggag
     2761 gatttatagt tactgtaggt tctgattctc atagggtaga agatatatgc aaagattttg
     2821 atgtggccta tgatatgctt aagtatcttg actttaaata tgtatcttta tttaaagaaa
     2881 gagaaactta ttttgtaaat atagaaaaag ttaaatctaa caatatagct tagagtgtgt
     2941 tttgaagtaa attaatggat agttaaaaag ttaatagtta taatattgta tcctctagaa
     3001 aaatactaga ggtttttatt ttgctaaaat aactaaatag aattaaattt aaatagtata
     3061 gtttatttta aattgaatag tttattgttg atatatttta ctattatata tttttattgt
     3121 gatataatag taaaatatat taacctatct ttagattata taaattatta taaaggaggg
     3181 aaattttaaa atgtctaata aaaataaaga aaatataact ttaagtaatc aaatcaaagg
     3241 aacaattcaa aatagtttaa caaaagaagc tatattacat ataccaatga gcaattatgc
     3301 ctatggttat gatagagaaa cactacatat aagacttaga actaaaaaaa atgaagcgaa
     3361 aagagtaatt ttacgaatag gagaccaata tgtgtgggat aaaggaggtg caggaggagg
     3421 aaatttaaat gcatctggag ttggttggtc tggtggaaca aatatagtaa tgagtaaaga
     3481 agtagaaact gaattatttg actattggat agctaagtgt aagcctttaa ataaacgctc
     3541 acgatatggt tttataatag aaggtcaaga ggaaaaactt ttatttacag aaaaaagaat
     3601 aatagagttg ggaaatgaaa atgatgaaaa ggaattatgt gaaataggta atttttttgg
     3661 atatccatat ttaaattata tagatatacc taaagtgcca aattgggtga aagatactgt
     3721 ttggtatcag atatttccag atagatttgc aaatggtgac ccgtctataa acccagaagg
     3781 agtagataaa tggggagcta ttccaaccag agataatttt acaggtggag atttacaagg
     3841 tgtgatagaa cacttagatt atttgagtga tttgggaata aacggaattt acttttgccc
     3901 tattacaatt ggaaaaacca atcatagata tgatacggta gattatatgg aggtagaccc
     3961 tacattagga gataaagaga ctttaaaaaa actaatagaa gaagcgcata agagaaatat
     4021 aagaataatg ttggatgctg tttttaatca tataggatat tattctaaac agtggcaaga
     4081 tgtagttcaa aataaggaaa attctcgata taaaaactgg ttttatataa aagatatgag
     4141 taaaattgat actccaatag aacaaataga tgaaaaaaat ataccttatg aaacctttgg
     4201 gtgtgaaaaa tatatgccta aacttaatac agaaaattca gaagtaataa aatatttatt
     4261 ggatgtaggc aagtactgga tacaggaatt tgatatagat gcgtggagat tagatgtttc
     4321 aaatgaagta gaccatgttt tttggagaaa gtttagagaa gaagtcaaaa aagtaaaacc
     4381 agacatttat atattgggag aaatttggca tggtagttta ccatggctaa tgggtgacca
     4441 atttgattca gttatgaatt acttgatgtc agaagccatg aaaaaattct tttgtacaga
     4501 tgagataaac gccgaagaat ttaagtatat gataaatgat gtaatggtaa gttatccaat
     4561 acaagttagt gaagttattt ttaatttact tggaagtcac gatactacaa gaatattgac
     4621 ttatgctaat ggaaatattg atagatttaa acttgcatat atgtttatgt ttgtacaaac
     4681 aggatgtcct tgtatatact atggtgatga aatcggaatg gaaggagaat taagttcaat
     4741 atctgaaggt caaagaaaat gtatgaaatg gaatgaagaa aaatggaata aggatatatt
     4801 tgattttatg aagaagatta ttagacttcg taaagaaaat aaagaactta ggtctatatc
     4861 aaatgaatgg gtgttagcag ataaggaaaa tggaacgatt atattgaaaa aagaatctat
     4921 ttctataata ataaataatt catctaaaaa tataattttg acgttaccag attatttagc
     4981 aaataaaaaa gtaaaagatt tatatgaaga agaaatagtt gatttaaaag aagaactaat
     5041 gttagagaaa tacaagttca ttattttaaa ataatacaaa aaagtattta ttttagattt
     5101 catgttaaat tattatacag tttaaataag tctttataaa cgataaaaaa atatggtcta
     5161 caagtgagtg aattgaaagt agattttaaa ttaaagactg agttagagta gataatttta
     5221 taaataatat cttaaataca agatagaaaa taaattgatt attagtctaa aaatttcttg
     5281 tagaaagagg aaataagaat gattgaagca tttatatttg atttagatgg tgtaattaca
     5341 gatactgcat attatcacta tatggcttgg agaaaactag cccataaagt tgggatagat
     5401 atagacacaa aatttaatga atctttaaaa ggcataagta gaatggagtc attggacagg
     5461 atattagaat ttggaaataa gaaatattca ttttcagaag aagaaaaagt gagaatggct
     5521 gaagaaaaaa ataattacta tgtatcattg atagatgaga taacttcaaa tgatattttg
     5581 ccaggtatag aaagcttgtt aattgatgta aaatctaata atataaagat aggtctatct
     5641 tctgcaagta agaatgcaat aaatgtatta aatcatttgg gtataagtga taaatttgat
     5701 tttatagctg atgcaggaaa atgtaaaaac aataaaccac atccagagat atttcttatg
     5761 tcagcgaaag ggcttaatgt aaatccacaa aattgcatag ggatagagga tgcaagtgca
     5821 ggtatagacg ctataaactc agctaatatg ttttctgttg gtgttggaaa ttatgaaaac
     5881 ttaaaaaaag caaatttagt tgtagattca acaaatcaat taaagtttga atatatacaa
     5941 gaaaagtata atgagtatat agttaggaga attatatgaa atgtttattt agtaatgtag
     6001 atgagtggaa gattatacaa gataagattg aaatcaaaga aaatagatta gcagagtcca
     6061 taatgagtat aggcaatgga tatatgggta tgagaggaaa ctatgaggaa aattatagtg
     6121 gagatacaca caaggggtct tatatagctg gagtatggtt tccagataaa actcgtgttg
     6181 gttggtggaa aaatgggtat ccagaatact ttggtaaaat tcctaattca gtcaactata
     6241 taggtgtaag aattttcata gatgatgtag aattagattt agcaaaatgt aaagtagaag
     6301 atttttatag agaattagat atgaaaaatg gtattttaaa tcgtaggttt attgtaaata
     6361 taaatgataa aaaatttgaa gttagggttg ctaggttttt aagtatatct gttaaggaac
     6421 ttgcagtaat taaatacagt ataaaatcat taaattctaa tactaaaata aaatttgtac
     6481 catatttaga ttcaaatata aaaaatgaag attcaaacta tgaggaaaag ttttggaatg
     6541 gaatttcttc aagttcttta gaatataaag ggagtattct ttctcgaaca aaggagaatg
     6601 catttaatac accagtattc actgtgggtt caatgatgta tattaagaca aatggtgatg
     6661 tagaagctat atctcatgag agtgattata attactgtga aaattcgata acaatggatg
     6721 ttttaaaaaa tgaggttgca agtatagaaa aatatgtatc tataacttca actagagatt
     6781 ataaggaaag tgagctatta agaaaatgtg aagacatttt aaatagagaa ctatctaaaa
     6841 gttatgatga tatattaaat gaacatacaa agttatggaa taaaagatgg gaaagtgcag
     6901 atgtaaaaat aaatggagat aaaagtagcc aacaaggtat aagatataat ttattccaac
     6961 tattttcaac atattatgga gaagattcgc gattaaatat aggtccaaaa ggatttactg
     7021 gtgaaaagta tggaggagct acttattggg atacagaagc attttgtgtt ccagtatatc
     7081 taggtgtagc agataaggag gtaactagaa atcttttaga atataggtac aatcagttag
     7141 aacaggcaaa ggataatgca aaaaaactag ggcttaaagg tgctttatat ccaatggtaa
     7201 catttgatgg agtagaatgt cataatgaat gggagataac atttgaggaa atccaccgaa
     7261 atggaagtat agtatatgca atatataact atacaaatta tacaggtgac tataaatata
     7321 taaaagaaaa aggaatagat gtaataatag aaatagctag attttgggca agtagagttc
     7381 atttgtctac aaaaaaagat ttgtatatga tacatggagt aacaggtcca aacgagtatg
     7441 aaaacaatat caataataat tggtatacta attatatagc taaatggtgt ttagattatg
     7501 ctgtagaaaa tatcttacga ttagagaaag agtgtaatga atgtattgac agaaataatg
     7561 tgactaggga agaagttgag ttttggaaaa taatatcaaa taaaatgtat ctgccgtatg
     7621 atgaggaact acaaataata attcaaaatg ataatttttt agataaagaa tttgtagaag
     7681 taaaggattt accaaaagaa aattttcctc ttaatcaaaa ttggtcttgg gataagattc
     7741 ttaggtcgtg ttttataaaa caagcagatg tattacaggg aatttactat tttggaaata
     7801 gatttactaa agaagaaaaa aagagaaatt ttgacttcta tgaaaaatat actgtacatg
     7861 aatcttcttt atcttctagt atttattcta ttattgcctc agaaatagat aacctagaaa
     7921 aggcttatga attatattca agaacagcta ggcttgattt agataattac aataatgata
     7981 caaatgatgg actgcacata acttcaatgt ctggttcatg gctttccatt gtacatggat
     8041 ttgcaggcat gagaacatgg aatgaaactc tatcttttga ccctaagttg ccaaaagagt
     8101 ggaaaaatta ttctttcaat ataaattata gagataatat tattaatgta gatgtatgta
     8161 gtgatttaat taaaatagaa aatttaaaag gtagaccaat aaaaattat
//
LOCUS       DAMKNB010000124         8154 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.130, whole genome shotgun sequence.
ACCESSION   DAMKNB010000124 DAMKNB010000000
VERSION     DAMKNB010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8154)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8154)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8154
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.130"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            <1..597
                     /locus_tag="PC494_003349"
     CDS             <1..597
                     /locus_tag="PC494_003349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDF3913819.1"
                     /translation="GLIKESSGQVLLNKHNLSNLAEHRRTQIVSRVFQDPSLGTCPSM
                     TVRENLSLALNKGKLLNLRKCLRYKRDFLENLLEGVSLDLKKYLDVQVKFLSGGQRQS
                     LSLIMSCLTNPSVLLLDEHTAALDPKTSNEVIELTNKIVREKNITTLMVTHNLKHALH
                     YGDRLIMLHKGEVVLDVKGKEKEQLTVEEILEKFEYAV"
     gene            728..1750
                     /locus_tag="PC494_003350"
     CDS             728..1750
                     /locus_tag="PC494_003350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDF3913820.1"
                     /translation="MINKKRLASLILAGALSISMLTGCSQGGDSGNSKQESNSKGKEV
                     KKIGITQLVEHPALDATRTGFVKALEKNGFKDGENIDIDFQNAQNDMPTTQSIASKFA
                     SDKKDLIFAISTPSAQAAFNATKDIPILITAVSDPVAAGLVKTLEKPGTNVSGTSDFV
                     SVDKGLELLKIFAPKAKTIGVMYNTSEVNSKVQVDALKEYASKNGFKVVEKGITTSNE
                     VNQGISSLVGKIDVLYVPTDNLVASSMPIVSKIATENKIPVIAAESGPVEKGALACQG
                     INYEKLGYKTGEMAVKILNGESVSDMPVATSDDTDIIVNEDILKALGMEKPSNENISY
                     VKTKQE"
     gene            complement(1914..2471)
                     /locus_tag="PC494_003351"
     CDS             complement(1914..2471)
                     /locus_tag="PC494_003351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HDF3913821.1"
                     /translation="MTEKEKMLSGKGYYANDELLVKEREYCKKLTRLFNNTLEDEYEK
                     REDILRQLFGSVGKQINVEQNIRCDYGYNIHVGENFFANYDCIFLDVCKIEIGDNVML
                     APNVQIYTAYHPIDAQLRNSGIEYGSPIKIGDNVWIGGGVIITPGITIGDNVVIGAGS
                     VVTKDIPPNTVAVGNPCRVIKKIEE"
     gene            complement(2477..3553)
                     /locus_tag="PC494_003352"
     CDS             complement(2477..3553)
                     /locus_tag="PC494_003352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfate/molybdate ABC transporter ATP-binding
                     protein"
                     /protein_id="HDF3913822.1"
                     /translation="MSLYVDIEKDLSSFKLKVEIKQEKGTLGFLGESGSGKSMTLKCI
                     AGLEKPTRGKIVLNDRVLFDSEKKINLSTQDRKVGFLFQNYALFPHMTVSQNIELGLL
                     KLSKSEKKEIVARYLDILKLNGFEGRYPWQLSGGQQQRVALARALATSPDILLLDEPF
                     SALDHHLRSNMEKELMNMLKDYKGDILFVTHDIEEAYRVCDDIIVYNKGEGLPKRPKK
                     ELFESPKYLIEAKITGCKNISKLNRLDKNTIYATDWGCELTLNREIGDNIEYVGIREH
                     HIKVLDSNEDLNEKLCFELINIVENPFTYTIYVRKTDLSNECVPIQIELEKSKMRFKK
                     GDRIYLDFPQEYLFCFRYNYNKKE"
     gene            complement(3554..4237)
                     /gene="modB"
                     /locus_tag="PC494_003353"
     CDS             complement(3554..4237)
                     /gene="modB"
                     /locus_tag="PC494_003353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdate ABC transporter permease subunit"
                     /protein_id="HDF3913823.1"
                     /translation="MGTDWSPLWISLKTSILSTIITFVIGIFVSYIMANYRGKWKGLI
                     DGLFTLPLILPPTVVGFFLLLLCGKNGFIGKFLLNFDRTLIFSWTATVISAVVVSFPM
                     MYRTSRSAFEQIDNNMLSAARTLGLNEWKVFFKIAVPLAWSGIIGGLVLSFARALGEF
                     GATLMIAGNIPGKTQTMPIAIFFAVEGGDMNKAMMWVMIIVAISIAMILLLNYWSEFQ
                     QKIIGKRCG"
     gene            complement(4386..5198)
                     /gene="modA"
                     /locus_tag="PC494_003354"
     CDS             complement(4386..5198)
                     /gene="modA"
                     /locus_tag="PC494_003354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdate ABC transporter substrate-binding
                     protein"
                     /protein_id="HDF3913824.1"
                     /translation="MKKILGILGLVACLTLGTVGCNSNEDKKDDGKQEKTTKSSDSVE
                     LNISAAASLKEAMAKIEEEYKKVDSNVKLTVNYGASGSLQQQIEQGAPCDLFISAGQK
                     QMKALDEEKLLVSDTMKDLVKNDLVLISSADSSVSGMKDLTTDKVKKIAVGEAESVPA
                     GKYADEVLTNLNLKDKLKDKLVFAKDVKEVLAWVQSGNADVGFVYFSDTVNNDKIKVV
                     EKTDEKTHSPITYPVSVIKASKNVDAAKKFEEFLLSESGQKIFEEFGYKKVE"
     gene            5391..6320
                     /locus_tag="PC494_003355"
     CDS             5391..6320
                     /locus_tag="PC494_003355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF3913825.1"
                     /translation="MDSLSSLTPVEVAELLKITKNTVYELIKRGELPSYKVGKKIRVD
                     TKDVEEYINSQKTGKVKDTHFNNKNIDINNNFKIIISGQDVILDILARSVEKKLDGIS
                     TFRSYIGSYNALYELYNGRVSIASSHLWDFETDEYNSTFVKKLLPGIPCVLINLAYRM
                     QGFYVAKGNPKEITTWEDLTKPSITIVNREKGSGTRVLLDGKLRLLNFNGKHIKGYDN
                     EELSHLGVASTVSRGIADVGLGNEKAALQVNNIDFIPLHKERYDLVIKKEDLQNPVYQ
                     TIINIINSPEFKAELQGLGGYDLTDTGKTIAKV"
     gene            complement(6481..6930)
                     /locus_tag="PC494_003356"
     CDS             complement(6481..6930)
                     /locus_tag="PC494_003356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3913826.1"
                     /translation="MKNKNNKDKNMLNIKVLRVLGVLLILFDYTGDTLNFYNFFAKPL
                     VSGNLYKTTGTDCIVFLLFIVECVYLVGRYILKVKINWSEIIENEKGNFINNLLVEKI
                     QEESNIVYNLLNSYVLPNIYKKARGLMFKTYHMLIYIKEKYYYVNIY"
     gene            complement(7133..8113)
                     /locus_tag="PC494_003357"
     CDS             complement(7133..8113)
                     /locus_tag="PC494_003357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDF3913827.1"
                     /translation="MKNSFKNCISLRNKFIIISIVFLLILLIVSYIFGKLVYNSSVGL
                     EQLIKNEDIVKIFSERKDKPLEKLKNYKTSELMIQSSNNYKLESLFITSNIKTRDTMI
                     LVHGIGSSYYEMLKVAYRYLDKGYNVLVYNQRNTGNSGGDNYTFGLYERYDLDSLVKF
                     VKNKFPEGRLGVHGFSMGAGTAAMHSEINSKDDKVDFYILDSPYSEMKDAIRMGVLEK
                     RIPDILINYVVTCGDLYNKFKSGFWYSDVKPYESVEKSNVPILFIHGTKDTVCNYQNS
                     KKMYDLVKHDKKDLWLIEGIGHVDGFEHDSTVYFNKIFKFIDSNVLSDKS"
BASE COUNT         2819 a         1349 c          977 g         3009 t
ORIGIN      
        1 gggcttataa aagaatcttc tggtcaagta ttattaaata aacataactt gtctaattta
       61 gctgaacaca gaagaactca aatagtaagt agagtttttc aagacccaag tcttggaact
      121 tgcccttcta tgactgttag agaaaacttg tctttagctc ttaacaaagg aaaactatta
      181 aatctaagaa aatgtcttcg ttacaaaaga gatttcttag aaaatttatt ggaaggtgta
      241 tctcttgatt taaaaaaata ccttgatgtt caagtaaaat ttttatcagg aggtcaaaga
      301 caatcattat cactaattat gtcgtgctta acaaatccat cagttttatt acttgatgaa
      361 catacagcag cacttgaccc aaaaacatca aatgaagtaa ttgaattgac taataagatt
      421 gtaagggaaa aaaatataac tacacttatg gttactcaca acttaaaaca cgctcttcat
      481 tatggtgata gattgataat gcttcataag ggtgaagttg tattagatgt aaaaggtaaa
      541 gaaaaagaac aattaacagt tgaagaaatc ttagaaaaat ttgaatatgc agtttaaaat
      601 aatatatcta ttgtattaaa ctcggcttta aaataaagtt aaaattacaa taattatggt
      661 tactttgtaa taattcatat gaatatatga acatatataa caataaattt ttgaggggga
      721 tataaaaatg attaataaaa aaagattggc aagtttgatt ttagctggtg ctcttagtat
      781 atctatgctt acagggtgtt cacaaggagg agactctggt aattcaaaac aagaaagtaa
      841 ttctaaaggt aaagaagtta aaaaaattgg tataactcaa ctggttgaac atccagcatt
      901 agatgccact aggacaggtt ttgtaaaagc attagaaaag aacggattta aagatggaga
      961 aaatattgat atagacttcc aaaatgctca aaatgacatg cctactacac aaagtattgc
     1021 gagtaaattt gcatctgata agaaggactt aatatttgct atatctactc catcagctca
     1081 ggcagcattt aatgctacta aagatatacc tatacttatt actgctgtga gtgaccctgt
     1141 tgctgctgga ttagttaaaa ctcttgaaaa gccaggcaca aatgtatctg gaacatcaga
     1201 ttttgtttct gtagacaaag gtttagaact tcttaaaata tttgctccta aggcaaaaac
     1261 tataggagtt atgtacaata ctagtgaagt aaattccaaa gttcaagttg atgctttaaa
     1321 agaatatgca tctaaaaatg gatttaaagt tgttgaaaaa ggtataacta cttcaaatga
     1381 agttaaccaa ggtatttcta gtttagttgg caaaatagac gtattatatg tccctacaga
     1441 taacttagtg gcttcttcta tgcctatagt ctctaaaata gctactgaga ataaaatacc
     1501 tgttatagca gctgaatctg gtccagttga aaaaggtgct cttgcttgtc aaggtatcaa
     1561 ctacgaaaaa ctaggttaca aaacaggtga aatggcagtt aaaattttaa atggcgaatc
     1621 agtatctgat atgcctgtgg ctacatcaga tgatacagat atcattgtta atgaagatat
     1681 attaaaagct ttaggtatgg aaaaaccttc taatgaaaat atttcttatg taaagactaa
     1741 acaagaatag aaagatattt tctatatacg attaatatgc ctgtttctat aaattaattt
     1801 atagaaacag gcatatattt ttattttaat gtattatcta tttaaagatt atatgtaaat
     1861 gctcttaatt tgtttgtata aattttactt gtataaactt tatacaatca tatttattct
     1921 tctattttct ttattactct acatggattt ccaacagcta cagtatttgg tggtatatct
     1981 tttgtgacta cacttcctgc acctattact acattatcac ctatagtaat tcctggtgtt
     2041 atgattactc ccccacctat ccatacatta tcacctattt ttataggaga accatactct
     2101 atgcctgaat ttctaagttg tgcatcaatt ggatgatagg ctgtatagat ttgaacgttt
     2161 ggagctaaca ttacattgtc acctatttca attttacata catctaaaaa aatacaatca
     2221 taatttgcaa agaaattttc gcctacatgt atgttatatc cataatcaca cctaatattt
     2281 tgttctacat ttatttgctt gccaactgaa ccaaatagtt gtcttaaaat atcttctctt
     2341 ttttcatatt catcctctaa agtattatta aacaatctag ttaatttttt acaatactct
     2401 ctttctttta ctaacaattc atcatttgca tagtatcctt tcccagacaa cattttttct
     2461 ttttcagtca tatagtttac tcctttttgt tataattgta tctaaagcaa aataaatatt
     2521 cctgtggaaa atctaaatat attctgtcac ctttcttaaa tctcatttta cttttttcca
     2581 attctatttg aataggtaca cattcgttag ataaatcagt ttttctaaca tatatagtat
     2641 atgtaaaagg attttctaca atgttaatca attcgaaaca taacttttca tttaaatctt
     2701 cattagaatc caagacctta atatgatgct ccctgattcc cacatattct atattatcac
     2761 ctatttctct atttaatgtc aactcgcatc cccagtctgt agcataaata gtatttttat
     2821 ccagtctatt taatttggat atatttttac accctgttat cttagcttct ataaggtact
     2881 ttggagattc aaagagctct tttttaggtc tctttggaag accttctcct ttgttgtaca
     2941 ctataatatc atcacaaact cggtaagctt cttcaatatc atgagtaaca aatagtatat
     3001 ctcccttgta atcttttaac atattcataa gttctttttc catattgctt cttaaatgat
     3061 ggtccaatgc tgagaaaggt tcatctaaaa gtaatatatc tggagatgtt gccaatgctc
     3121 tagctagtgc taccctttgt tgttgaccac cagataattg ccaagggtat ctcccctcaa
     3181 acccatttaa tttaagtata tctaagtacc ttgctactat ttcctttttt tcactcttac
     3241 ttagttttaa aagcccaagt tctatatttt gacttacagt catatgtgga aacaaagcat
     3301 agttttgaaa taaaaatcct acctttctat cttgtgttga taaatttatc ttcttttcag
     3361 aatcaaatag aactctatca tttaatacaa ttttacctct tgttggtttc tcaagccctg
     3421 ctatacattt taatgtcata ctttttccag aaccagattc tcccaaaaac cccagagtac
     3481 ctttttcttg tttaatttct acctttagtt taaaagagga taaatctttt tcaatatcca
     3541 cgtataagct caactatcca cacctctttc ctataatttt ctgctgaaat tccgaccaat
     3601 aatttagtaa taaaatcatt gctatagata ttgctacaat aatcataacc cacatcatag
     3661 ctttattcat atctccgcct tcaacagcaa aaaatatagc tattggcata gtttgagttt
     3721 ttccaggtat atttccagct atcataagtg tagcaccaaa ttctccaaga gctctggcaa
     3781 acgacagcac caatccacca attattccag accatgctaa tggaactgca atcttaaaaa
     3841 atactttcca ttcattaaga cctaatgttc tagcagctga caacatatta ttatcaatct
     3901 gttcaaaagc tgaccttgaa gttctataca tcataggaaa agacaccact actgctgaaa
     3961 ttacagttgc tgtccaacta aatattaaag tcctatcgaa atttaataaa aactttccta
     4021 taaatccatt cttcccacat agtaataata aaaagaaacc tacaactgtt ggtggcaaaa
     4081 ttagtggaag tgtaaatagt ccatctataa gacccttcca cttacctcta tagttagcca
     4141 taatatatga cacaaatatt cctattacaa aagttattat tgttgacaaa atagatgtct
     4201 taagtgatat ccataagggt gaccaatctg ttcccatctt tccctcctta attttaaatg
     4261 gaaatagtga aactaataac tctattaatt tcactatttc cattttatta taatacacaa
     4321 ttattttcaa ttttcattta tttatatata atttatactt aattacacat aatttatttc
     4381 taagtttatt ctactttttt atatccaaat tcttcaaaaa tcttttgtcc tgactcactt
     4441 aataaaaatt cttcaaattt cttagcagca tctacgtttt tactagcttt aattactgaa
     4501 actggatatg taataggcga atgagttttt tcgtctgttt tttcaactac ttttatctta
     4561 tcattattga cagtatcact gaagtaaacg aatccaacat cagcatttcc tgattgcacc
     4621 catgctaaaa cttcttttac atcttttgca aatactagct tatcttttaa cttatctttt
     4681 aaatttaaat tagttaacac ctcatctgca tacttaccag ctggaacact ttcagcttca
     4741 ccaacagcaa ttttcttcac tttatctgta gtcaaatctt tcatacctga tacactactg
     4801 tcagcagaag aaataagaac taaatcattt tttactaaat ctttcatagt atcagaaact
     4861 aataacttct cttcatccaa agctttcatt tgtttttgac ctgctgaaat aaataaatca
     4921 caaggtgctc cttgttctat ttgttgttgt aatgagcctg atgctccata gttaactgta
     4981 agttttacat ttgaatcaac ttttttatat tcttcttcaa tctttgccat tgcttctttt
     5041 aaacttgcag cagccgatat atttaactct actgaatcac tacttttagt tgttttttct
     5101 tgttttccat catctttttt gtcttcatta ctattgcacc caactgtccc caaagttaaa
     5161 catgcaacta atcctaatat tcccaatatt tttttcataa caatctccct ttttgtaaat
     5221 ttgatacaca ttttaacatg ttttattatg ttttatcatg ttttgttata tatagtttaa
     5281 ttatatatac atgataataa attttcaagt aatttattta cactactttt aaatattttg
     5341 ctacattttc ctttttttaa tgttaaaata accttatatg gaggtggatt atggactcat
     5401 tatcatcttt gacacctgtc gaggtagctg aattattaaa gataacaaaa aatactgtat
     5461 atgaattaat caaaagaggt gaacttcctt cttataaagt agggaaaaaa ataagagttg
     5521 atactaaaga tgttgaagaa tatatcaaca gccaaaaaac tggtaaagta aaggatacac
     5581 atttcaacaa taaaaatata gatataaata ataatttcaa aattattatt tctggtcaag
     5641 atgtaatatt agacatttta gctaggtctg ttgaaaaaaa attggatgga ataagtacat
     5701 ttcgctctta tataggtagt tataatgctt tgtatgagtt atataatggc agagtttcta
     5761 tagcatcatc ccatctatgg gatttcgaaa cggatgaata taatagcact tttgttaaaa
     5821 agctattgcc aggaatacca tgtgtactta taaatctagc ttatagaatg caaggtttct
     5881 atgttgctaa aggaaatcct aaagagataa caacctggga ggatttaaca aaaccaagta
     5941 taaccattgt aaatagggaa aaaggttctg gaactagggt tttactagat ggtaaactta
     6001 gacttctaaa ctttaatggt aaacatataa aaggttatga taatgaagaa ttatcacatc
     6061 ttggagttgc aagtactgtt tctcgtggaa tagcagatgt tggtttggga aatgaaaaag
     6121 ctgctttaca agtaaataat atcgacttta ttcctcttca caaagagcgc tatgatttag
     6181 ttattaaaaa agaagactta caaaatccag tttaccaaac tataattaac ataataaact
     6241 ctcctgagtt taaagctgaa cttcaaggtc ttggcggata tgatttaact gatactggaa
     6301 aaactatagc aaaagtttaa gattaaaatc gcaatctatt ttataagatt tataattttt
     6361 cacaaaattt ataacttaaa cacgaaataa attgcgattt tagtgtctca aaaaatttat
     6421 gtctttcatt ttatcatcca atacaaaata taatataatt aattgtgcaa tcatattata
     6481 ttaatatata tttacataat agtatttttc tttaatgtag attaacatat gatatgtttt
     6541 aaacatcaat ccccttgctt tcttatatat atttggcaac acatatgagt ttaataaatt
     6601 atatacaatg ttgctttctt cttgtatttt ttcaaccaac aagttattta taaaattacc
     6661 tttctcattt tcaataatct cactccaatt tatcttaact tttaatatat atcttcccac
     6721 taggtataca cactctacaa taaataataa aaatacaatg cagtcagtac ctgttgtctt
     6781 atataaatta cccgatacta atggctttgc gaagaaatta taaaaattca aagtatcacc
     6841 cgtataatca aaaagtatta atagcactcc tagaactctc aatactttaa tattcaacat
     6901 gtttttatct ttattatttt tgtttttcat atatactacc tctcttttct ttagatttga
     6961 ttgtaatcta atactaactc ttttatttga ggtataaatg aatttaattg gtagttattt
     7021 tcatttttac tagaaattaa ttcacattac taaacaaaac ttatatttaa acataaaaat
     7081 agcctatcta tcttttaata aatacaaaaa taaataagct actaatattc aattaacttt
     7141 tatcacttaa aacattacta tctataaatt taaatatttt attgaagtat actgtactat
     7201 catgttcaaa tccatcaaca tgaccaatac cttctataag ccataggtct tttttatcat
     7261 gtttaactaa atcatacatt ttcttgctat tttgataatt acaaacagta tcttttgttc
     7321 catgtataaa cagtatgggt acattagatt tctcaactga ctcatatggt tttacatcac
     7381 tgtaccaaaa tccagattta aacttattat ataaatctcc acaagtcacc acataattga
     7441 ttaatatatc tggtattcgt ttttctagta ctcccattct aattgcatct ttcatttcag
     7501 aataaggaga atccagtata taaaaatcga ccttatcatc ttttgaattt atctctgaat
     7561 gcatagcagc tgtccctgcc cccatggaaa atccatgcac tcctaatctc ccttcaggaa
     7621 atttattttt tacaaattta actagactat ctaaatcata cctttcataa agaccaaatg
     7681 tgtaattatc tccaccacta ttaccagtat ttctttgatt ataaactaat acattataac
     7741 ctttatctaa atatctatat gctaccttta acatttcata gtaactactt ccaattccat
     7801 gaacaagtat catagtatct cttgtcttta tatttgaagt tataaaaaga ctttcaagct
     7861 tgtaattatt agaactttgt atcattaatt cagatgtctt gtagtttttt aatttctcca
     7921 gtggtttatc ttttctctca gaaaatattt ttactatatc ttcgtttttt attaactgct
     7981 ctaaaccaac tgaactatta tacactaatt ttccaaatat ataagataca attaatagga
     8041 ttaatagaaa cacaattgat ataattataa atttatttct taaactaata caatttttaa
     8101 aactattttt catatttatt taccatacaa ttttcctata ttatattttc taag
//
LOCUS       DAMKNB010000125         7932 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.131, whole genome shotgun sequence.
ACCESSION   DAMKNB010000125 DAMKNB010000000
VERSION     DAMKNB010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7932)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7932)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7932
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.131"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            27..101
                     /locus_tag="PC494_003358"
     tRNA            27..101
                     /locus_tag="PC494_003358"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:59..61,aa:Thr,seq:tgt)
     gene            116..200
                     /locus_tag="PC494_003359"
     tRNA            116..200
                     /locus_tag="PC494_003359"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:150..152,aa:Tyr,seq:gta)
     gene            210..293
                     /locus_tag="PC494_003360"
     tRNA            210..293
                     /locus_tag="PC494_003360"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:244..246,aa:Leu,seq:tag)
     gene            317..391
                     /locus_tag="PC494_003361"
     tRNA            317..391
                     /locus_tag="PC494_003361"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:349..351,aa:Gly,seq:gcc)
     gene            416..492
                     /locus_tag="PC494_003362"
     tRNA            416..492
                     /locus_tag="PC494_003362"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:450..452,aa:Arg,seq:tct)
     gene            502..577
                     /locus_tag="PC494_003363"
     tRNA            502..577
                     /locus_tag="PC494_003363"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:535..537,aa:Gln,seq:ttg)
     gene            586..661
                     /locus_tag="PC494_003364"
     tRNA            586..661
                     /locus_tag="PC494_003364"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:619..621,aa:Lys,seq:ttt)
     gene            664..752
                     /locus_tag="PC494_003365"
     tRNA            664..752
                     /locus_tag="PC494_003365"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:698..700,aa:Ser,seq:tga)
     gene            756..831
                     /locus_tag="PC494_003366"
     tRNA            756..831
                     /locus_tag="PC494_003366"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:789..791,aa:Phe,seq:gaa)
     gene            838..911
                     /locus_tag="PC494_003367"
     tRNA            838..911
                     /locus_tag="PC494_003367"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:872..874,aa:Met,seq:cat)
     gene            926..1002
                     /locus_tag="PC494_003368"
     tRNA            926..1002
                     /locus_tag="PC494_003368"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:960..962,aa:Ile,seq:cat)
     gene            1020..1096
                     /locus_tag="PC494_003369"
     tRNA            1020..1096
                     /locus_tag="PC494_003369"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1054..1056,aa:His,seq:gtg)
     gene            1105..1180
                     /locus_tag="PC494_003370"
     tRNA            1105..1180
                     /locus_tag="PC494_003370"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1138..1140,aa:Lys,seq:ttt)
     gene            1188..1261
                     /locus_tag="PC494_003371"
     tRNA            1188..1261
                     /locus_tag="PC494_003371"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1220..1222,aa:Cys,seq:gca)
     gene            1269..1345
                     /locus_tag="PC494_003372"
     tRNA            1269..1345
                     /locus_tag="PC494_003372"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1303..1305,aa:Arg,seq:acg)
     gene            1358..1433
                     /locus_tag="PC494_003373"
     tRNA            1358..1433
                     /locus_tag="PC494_003373"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1391..1393,aa:Val,seq:tac)
     gene            1509..1922
                     /locus_tag="PC494_003374"
     CDS             1509..1922
                     /locus_tag="PC494_003374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3913828.1"
                     /translation="MYIVIGNEIVDSEELKIIIDKNSEFKVEKDLSKSTKREDVIAYQ
                     LSIDLNYLDSLINEQCNLASLSDEEKFDEYMTLSDELALDLEELMPKYTIINARAYKL
                     DEVDGIVKIILAVAYADLGHLKLSDVVKRLSRQVD"
     gene            2230..5661
                     /locus_tag="PC494_003375"
     CDS             2230..5661
                     /locus_tag="PC494_003375"
                     /EC_number="6.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate carboxylase"
                     /protein_id="HDF3913829.1"
                     /translation="MLKKFNKILVANRGEIAIRIFRACSELGIKSVGIYSKEDKYGLF
                     RTKADESYLIGEGKGPIDAYLDMDGIIDLAKRKKVDAIHPGYGFLAENAEFARKCEEN
                     GITFIGPSSKVMNMMGDKINSKKIAKEVNVQTIPGVEKAIRSTEEAKEVANKIGYPVM
                     IKASNGGGGRGMRIVHREEDLELEYETACSESRKAFGEDIIFIEKYIADPKHIEVQIL
                     GDNYGNIVHLYERDCSVQRRHQKIIEYAPAFSLDDKVRKEICEDAVKLSKHVGYSNAG
                     TLEFLVDANGGHYFIEMNTRVQVEHTVTEMVTGIDIVQSQILIAQGYSLDSEEINIKS
                     QDDVEIRGYSIQCRITTEDPKNKFMPDTGKIQVYRTGSGFGIRLDGGNGFTGANISPH
                     YDSLLVKTISWDRTFQGAINKTIRSIKELRVRGVKTNVGFLVNVLNNPIFSNGKCSTK
                     FIDENPDLFEITESKDRGTKLLQFIGDVIVNDNACKEKPLFDALHDPRMDKDGSKSEG
                     SKILFDKLGKSAYIEKIKNDKKLLLTDTTMRDAHQSLLATRIRTYDLLKAAKPTEKYQ
                     KDLFSLEMWGGATYDVAYRFLKESPWRRLQKLREEIPSIMFQMLLRASNGVGYKNYPD
                     NVIEEFTKESARQGIDVFRIFDSLNWVENMKPSINTALETGKIVEATMCYTGDILDKT
                     KTKYNLEYYIKMAQELESLGADIIAIKDMSGLLKPYSAYTLVKELKKNVKAPIHLHTH
                     DTSGNGVATCLMASEAGVDIIDAALESMAGLTSQPSLNAIVEALKNTERDTGIDLFGY
                     DELGKYYKDLRKVYNKFESDLTNSCAEIYNFEIPGGQYTNLKPQADSLGLVNRFDEVK
                     EKYKEANEVVGDIIKVTPSSKVVGDLAIFMTKNKLDKDNIIEEGKNLSFPDSVVDYCK
                     GMIGQPEGGIPKDLQEVVLKGEEAITVRPGSLLPAEDFDEIAKYLNEKYDINANIRNV
                     ISYALYPKVYEDYIKHLQHYNDISKLESDVFFYGLNKNEECEVEIEEGKVLTIRLVEI
                     GEVKENGFRTIGFELNGMVREVEIKDKNFSGKINNVEKADMNDPLQIGASIPGKVIKI
                     MVKEEDEVKANQPLIVIEAMKMETIIVAKTDGVIKSIKVKEDDMVEDKQLLMIMK"
     gene            5903..7831
                     /locus_tag="PC494_003376"
     CDS             5903..7831
                     /locus_tag="PC494_003376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HDF3913830.1"
                     /translation="MKVYDSKMLRNVAVLGHSGCGKTNLIETIAYTANTNKIPKLTDK
                     VNMTYSMGLIPIEYNDYKFNLLDTPGYFDFSGDVVSSLRASDAAIIVIDATAPIQVGT
                     EKSLELTESIPKIMFINKIDNEKARYKDAIAMLREKYNNKIVPMISPIYKDKNFVKLH
                     NVFENIDDLEGEFKEQAMSVKEALMELIAETDDQILDKYFNGEELTTEEIQKGIIIGI
                     QRGDIIPVICGSTINNIGTKEILDTISSYLEPIFTEESKPFRGLVFKTMVDPFVGKMS
                     YIKITEGVLSKDKDVFNINKNVKEKIANIYTLRNSELVEIEKAKAGDIVVITKVNSLK
                     TGDTISADKDAEALEKIDFPKPQIYYAVTPKNKGDEEKVASVLNKLVEEDPTLHWYRN
                     TETKQALLGGQGELHIKTIKNKMKDKFGVDVELNDLKVPYRETIKGTADVQGKHKKQS
                     GGHGQYGDVKIRFERCESDFEFTEEIFGGSVPKQYIPAVEKGLKDSMQKGILAGYPVT
                     NIKATLYDGSYHDVDSSEMAFKMAASAAFKKGMEEAHPILLEPIMKLKITVPEEYMGD
                     VMGDINKRRGKIFGMEPDDKGKQIIFAEAPQAETFKYAIDLRAMTQGRGYFEMELERY
                     GEVPSQFAEKIIGLATAK"
BASE COUNT         3104 a         1015 c         1594 g         2219 t
ORIGIN      
        1 ccccttccag gtcgccaaaa taaaatgctg gtgtggctca acggtagagc agctgacttg
       61 taatcagcag gttgtaggtt cgattcctat caccagctcc atataaaatt aatacggagg
      121 atttcccgag cggccaaagg gggcagactg taaatctgtt gtcatcgact tcggtggttc
      181 gaatccacca tcctccacca aaaaaatgcg cggatgtggc ggaattggca gacgcactag
      241 acttaggatc tagcgccatt ggcgtggggg ttcgactccc ttcatccgca ccatttttat
      301 ttaatttaat aaacgagcgg gaatagttca gtggtagagc gcaaccttgc caaggttgaa
      361 gtcgcgagtt cgaatctcgt ttcccgctcc aaattttatg tttatgttgt aatgtgggtg
      421 catagctcag ctggatagag caacgccctt ctaaggcgtg tgtccggggt tcgaatccct
      481 gtgcgctcac cacatatata ttggggatta gccaagtcgg taaggcacat gactttgact
      541 catgtatgcg taggttcgag tcctgcatcc ccagccaaac agtatggtct attagctcag
      601 tcggtagagc acctgacttt taatcagggt gtcccgcgtt cgagtcgcgg atagatcacc
      661 aatggagagg tgtccgagtg gtttaaggag ctggtcttga aaaccagtga cttcgaaagg
      721 ggccgtgggt tcgaatccca ccctctccgc caaatgccca gatagctcag tcggtagagc
      781 aggggactga aaatccccgt gtcggtggtt cgattccgcc tctgggcacc aaaatgtggc
      841 ggtatagctt agttggctag agcgttcggt tcatacccga aaggtcatag gttcgactcc
      901 tattaccgct actaaaattt aatgtgggcc attagctcag ttggttagag cgcccggctc
      961 ataaccggta ggtctggggt tcgagtccct gatggcccac cacattaaat taacttatgg
     1021 tgggtatagc tcagttggtt agagcgccag attgtggctc tggaggtcgt gagttcgact
     1081 ctcattatcc accccaactt atatggtcta ttagctcagt cggtagagca cctgactttt
     1141 aatcagggtg tcccgcgttc gagtcgcgga tagatcacca aaaaggcggc gacatagcca
     1201 agtggtaagg cagtggactg caactccttg atccccagtt cgaatctggg tgtcgcctcc
     1261 aataaaatgc gctcatagct caactggata gagtgtctga ctacgaatca gaaggttagg
     1321 ggttcgagtc cctttgggcg caccatatga atagcgaggg attatagctc agctgggaga
     1381 gcacctgcct tacaagcagg gggtcacagg ttcgagccct gttaatccca ccagtgcaaa
     1441 cctctagtaa aactactaga ggttttattt ttgattgaaa aagtttttat atttaggagg
     1501 taaaaaattt gtatatagta ataggaaatg aaatagttga tagtgaagaa cttaaaataa
     1561 ttatagataa aaatagtgaa tttaaagttg aaaaagattt aagtaaaagc acaaaaagag
     1621 aagatgtaat agcatatcag ttaagtatag atttaaatta cctagattct cttataaatg
     1681 agcaatgtaa tttagccagt ctatctgatg aagagaaatt tgatgaatat atgactttgt
     1741 ctgatgaact tgcactggat ttagaagagt taatgccaaa atatacaata ataaatgcta
     1801 gagcatataa attagacgag gtagatggaa ttgtaaaaat aatactagct gtagcgtatg
     1861 cagatttagg gcacttaaaa ctttctgatg tagtaaagag gctatctaga caagtagatt
     1921 aggatatgaa tatgaactat attaaaaaaa tgtataaaat cttacgtaaa gatgaaaata
     1981 attatgtaaa catagaaaaa acagtataaa atcaagtcaa ttgtagaaat tttcacataa
     2041 attcatctga aattctataa aaaatgcctt aattttaatg aggtaaatcg agtttacaca
     2101 gtctaaaaat tacttatatt tataaattta tcttattaat taaggaactt tcttaaacat
     2161 cttcaaaaat aaagtatttt agtctataat ctttaatatt acacaaacaa taaaggagaa
     2221 gaatagagta tgcttaaaaa gtttaataaa atactagtgg ctaatagagg cgaaatagct
     2281 ataagaatat ttagagcctg ttcagaattg gggataaaaa gtgttggtat atacagtaag
     2341 gaagataagt atggattgtt tagaacaaaa gcggatgaat catatttgat aggagaaggt
     2401 aaagggccaa tagatgcata tttagatatg gatggaataa tagacctagc aaagagaaaa
     2461 aaagttgatg ctatacatcc aggatatggt tttctagcgg agaatgcaga atttgctcgt
     2521 aaatgtgaag agaatggaat tacttttata ggaccatcat ctaaggtaat gaatatgatg
     2581 ggggataaga ttaactctaa aaaaatcgca aaagaagtta atgttcaaac tataccagga
     2641 gtagaaaaag caataagaag tactgaagaa gcaaaggaag ttgcaaacaa aataggatat
     2701 cctgttatga taaaagcatc taatggcggt ggcggtagag gtatgagaat tgtacatcgc
     2761 gaagaagact tagagcttga atatgaaact gcttgtagtg aatcaagaaa agcttttgga
     2821 gaagatatta tatttataga aaaatatata gctgatccaa aacatataga agttcaaata
     2881 ttaggtgata attatggaaa tatagttcac ttatatgaaa gagattgttc agttcaaaga
     2941 agacatcaaa aaataataga atatgcacca gctttttcgt tagatgataa agtaagaaaa
     3001 gagatatgtg aagatgcagt taagttatca aaacatgtgg gttattctaa tgcgggaaca
     3061 ttagaatttt tagtagatgc aaatggtggg cattatttta tagagatgaa cacaagagta
     3121 caggttgaac atactgtaac agagatggtt acaggaatag atatagttca aagtcaaata
     3181 ctaatagccc aaggttacag cttagatagt gaagaaatta atataaaatc acaagatgat
     3241 gtggaaataa gaggttactc tatccaatgt agaataacta cagaagaccc taagaataaa
     3301 ttcatgcctg atacaggtaa aattcaagtt tatagaactg gttcaggatt tggtataaga
     3361 ctagatggag gaaatggatt tacaggggca aacataagtc ctcattatga tagtttattg
     3421 gttaagacaa tatcttggga tagaacattc caaggagcaa taaataaaac tataagatct
     3481 ataaaagaac ttagagttag aggtgttaaa actaatgtag gattcctagt taatgtttta
     3541 aataatccta tattctcaaa tggtaaatgt agtactaagt ttatagatga aaatccagat
     3601 ttatttgaaa taacagaaag taaagacaga ggaacaaaat tacttcaatt tataggagat
     3661 gtaattgtaa atgataatgc ttgtaaagaa aaaccattat ttgatgcatt acatgaccca
     3721 agaatggata aggatggttc aaaatcagaa ggaagtaaaa tacttttcga taagttaggt
     3781 aaatctgcat atatagaaaa gataaaaaat gataagaaat tactattaac agatacaaca
     3841 atgagagatg cacatcaatc attattagca acaagaataa gaacatatga cttattaaaa
     3901 gctgctaagc caacagaaaa atatcaaaag gatttattct cacttgaaat gtggggagga
     3961 gctacttatg atgttgcata tagattttta aaagaatctc cttggcgtag attacaaaag
     4021 ctaagagaag aaataccaag cataatgttc caaatgttgc ttagagcatc aaatggagtt
     4081 ggatataaaa actatccaga taatgtaata gaagaattta caaaagaatc tgctagacaa
     4141 ggtatagatg tatttagaat atttgattca ttaaactggg ttgaaaatat gaaaccatct
     4201 attaatacag ctttagaaac tggaaaaatt gttgaagcaa ctatgtgtta tacaggtgat
     4261 atactagata agactaaaac taaatacaat ctagaatatt atataaaaat ggcacaagaa
     4321 ttagaaagct tgggagcaga cataatagca ataaaagata tgtcaggtct tcttaaacca
     4381 tattcagctt acacattagt taaagagtta aagaaaaatg taaaagcacc aatacattta
     4441 cacactcatg atacaagtgg aaatggtgta gcaacttgtt taatggcgtc agaagctgga
     4501 gtagacataa ttgatgctgc attagaatct atggcaggac ttacaagtca gccatcactt
     4561 aatgctatag tagaggcact taagaataca gagagagata caggaataga tttatttgga
     4621 tatgatgagt taggaaaata ttataaggat ttaagaaaag tttataataa atttgaaagt
     4681 gatttaacta attcttgtgc agaaatatat aattttgaaa taccaggagg ccaatataca
     4741 aacttaaaac ctcaagctga tagtttagga ttagttaata gatttgatga agttaaagaa
     4801 aaatataaag aagctaatga agttgtagga gatataataa aagtaactcc atcttcaaaa
     4861 gttgtaggag acttagctat ctttatgact aaaaataaat tagataaaga caatataata
     4921 gaagaaggta aaaatttatc attcccggat tctgttgtgg attactgtaa aggtatgatt
     4981 ggtcaaccag aaggtggaat accaaaagat ttacaagagg tagttctaaa aggtgaagaa
     5041 gctataacag taagaccagg ttcattatta ccagcagaag attttgatga aatagctaaa
     5101 tatctaaatg aaaagtatga tataaatgct aatataagaa atgttataag ttatgcttta
     5161 tatccaaaag tatatgaaga ttatatcaaa catctacaac attataatga tatatctaaa
     5221 cttgaaagtg atgtattctt ctatggatta aataaaaatg aagaatgtga agtagaaata
     5281 gaagaaggta aggtattaac aataagatta gttgaaattg gtgaagttaa ggaaaatgga
     5341 tttagaacta taggatttga gttaaatgga atggttagag aagtagaaat aaaagataag
     5401 aatttctctg gaaaaattaa taatgttgaa aaagctgata tgaatgaccc tcttcaaatt
     5461 ggagcaagca taccaggaaa agttataaaa ataatggtta aagaagaaga tgaagtaaaa
     5521 gcaaatcaac cattaatcgt tatagaggct atgaagatgg aaactataat agttgctaag
     5581 actgatggag taattaagtc aatcaaagta aaagaagatg atatggttga agataaacaa
     5641 ttattaatga taatgaagta atttaattaa aataaattaa aaagcactct gaaatgttta
     5701 ataaaaaatg ttttagagtg tttttattta ttttaattaa atatttgtta aaaaaaagag
     5761 gacaattacc tccagatgta gaaataaagc tagtaaggaa aatgttatct aaaaattcta
     5821 aatatagtaa atattttcca taatatttct taggaaataa cagcaaagat aaaatacata
     5881 aatttaaaag gtgggtgctt atatgaaggt ttatgatagt aaaatgttga gaaatgtagc
     5941 ggtattagga catagcggat gtggaaaaac aaatctaatc gaaactatag cttacacagc
     6001 aaacactaat aagataccta aattaacaga caaggtaaat atgacttata gcatgggatt
     6061 aatacctata gagtataatg attataagtt taacttattg gataccccag gatattttga
     6121 ctttagcgga gacgttgtgt catctcttag agcaagtgat gcagcaataa tagtaataga
     6181 tgcaacagcg cctattcaag ttggtacaga gaaatcatta gaactaactg agagtattcc
     6241 taagataatg tttataaata aaatagataa tgaaaaggca agatacaaag atgcaatagc
     6301 aatgttaaga gaaaaataca ataataagat agttcctatg ataagtccta tatacaaaga
     6361 taaaaacttt gtaaagttac ataatgtttt tgaaaacata gatgatttag aaggtgaatt
     6421 taaggaacaa gctatgagtg ttaaagaagc attaatggaa cttatagcag aaactgatga
     6481 ccaaatatta gataaatatt ttaatggaga agaactaact acagaagaga tacaaaaagg
     6541 tattattata ggtatacaaa gaggtgatat tatacctgta atatgtggtt caactataaa
     6601 taatataggc acaaaggaaa tattagatac aatatcaagt tatttagaac ctatctttac
     6661 agaggaaagc aaaccattta ggggattagt atttaaaact atggttgacc catttgttgg
     6721 aaagatgtca tatataaaaa ttactgaggg tgtactttct aaggataaag atgtttttaa
     6781 tataaataaa aatgtaaaag aaaaaatagc taatatatat acattgagaa atagtgaatt
     6841 agtagaaata gaaaaagcta aagctggtga tatagtagtt ataactaaag ttaattctct
     6901 aaaaacagga gacactatat ctgcagataa agatgcagaa gctttagaaa agatagattt
     6961 tcctaaacca caaatatatt atgcagtaac tcctaagaat aaaggtgatg aagaaaaagt
     7021 agcatctgta ttaaataaac tagtagaaga ggaccctaca ttacattggt atagaaatac
     7081 agagacaaaa caagcacttt taggaggtca aggagaactt catataaaaa caattaaaaa
     7141 taaaatgaaa gataagtttg gtgttgatgt tgaattgaat gaccttaaag ttccttatag
     7201 agaaactata aaaggaacag ctgatgtaca aggaaaacat aaaaagcaat caggtggtca
     7261 tggtcaatat ggagacgtaa aaataagatt tgaaagatgt gaatctgatt ttgaatttac
     7321 agaagaaata tttggtggtt ctgtaccaaa acaatatata ccagcagttg aaaaaggttt
     7381 aaaagactct atgcaaaaag gtatattagc aggatatcct gttacaaaca taaaagctac
     7441 gctttatgat ggttcatacc atgatgtaga ctcttctgaa atggccttta agatggcagc
     7501 aagtgcagcc tttaaaaaag gtatggaaga agcacaccca atactactag aacctataat
     7561 gaaacttaag ataactgttc cagaagaata tatgggagat gtcatgggtg atataaataa
     7621 gagaagagga aaaatatttg gaatggaacc agatgacaaa gggaaacaaa taatatttgc
     7681 agaagctcca caagcagaga catttaaata tgcaatagat ttaagagcaa tgacacaagg
     7741 tagaggatac tttgaaatgg aattagagag atatggagag gttccatcac agtttgcaga
     7801 aaaaataatt gggttagcta ctgcaaagta atgaacaaaa taaatagaaa aataattaat
     7861 atatattatt aaaaatattt ttagggtttt aactaggtat aggtttatgt taggtaaact
     7921 tatacctagt tt
//
LOCUS       DAMKNB010000126         7882 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.132, whole genome shotgun sequence.
ACCESSION   DAMKNB010000126 DAMKNB010000000
VERSION     DAMKNB010000126.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7882)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7882)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7882
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.132"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            complement(65..1345)
                     /locus_tag="PC494_003377"
     CDS             complement(65..1345)
                     /locus_tag="PC494_003377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011572945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HDF3913831.1"
                     /translation="MTKEEYFEERQKLIDQAQKLLDDEKMEEAEEVTNKIKNLDSSFE
                     TEVKARANLRALEDNNKIDPIIADMMFNNGSISLSNGETSYSVTSQPIEKNNLYSYTA
                     REGNKIRALGKKDSFRSSLNINNSQNLSLGKYIKGMHIGDWKDANVEMEAYKALNTST
                     GSTLIPRELSAEIIDLARNKMALSNINVIPMETNNLTLAKVKSDPKFSFKKELEVATQ
                     SDMEFEGIELRTKTVYGYMKISLELLESAGNIDAIISNAIAESIASAIDKAGLYGVGE
                     NEPKGILTYTGINKVNESLISTSKYNGLVKGIGLIKKANGEATDILYNSNTETDLNLL
                     VDTTGQPLNEPKVVEQIEKTTSNQIKDNQAIVFDRNSILMGLQNSIRIETSREMGFTD
                     GSVYFRVYGFVDFAVMNEKNITLIEYSKTPQDAE"
     gene            complement(1376..1939)
                     /locus_tag="PC494_003378"
     CDS             complement(1376..1939)
                     /locus_tag="PC494_003378"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3913832.1"
                     /translation="MKTKTITIRVEESLIDKLNYYKELDPDGNMSQSEFMCRAIEEKC
                     ERIRKQRSGGFELLIPNPQNVYSTDDEKKTIVLKLAECANEINKTNVSLDFGIDYLVG
                     YAKQRLITDTKELRKKFETNFKKDLEFETSLELDLESKTEEELEKMFEEYKNDIFSSE
                     IISMIKDELLRRDDIRDAIAETKKLNK"
     gene            complement(2141..4750)
                     /locus_tag="PC494_003379"
     CDS             complement(2141..4750)
                     /locus_tag="PC494_003379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011572948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HDF3913833.1"
                     /translation="MKIDIKQLIDIIKNANIDELYLRDIGVDTTQKGNVPCPVHGGKD
                     KNFQFDLNKRIYTCYSHGCVVGADIIELCRTYEHFEKPIEAILFLANKYNISLPINKS
                     KTNTKKTNNTIKNIYIKKKDINSFIEEKKQEAFKNNDIELAFEFECMTDKDKRKYYLD
                     NNIKIKSMLEKQNYSSYKADSIINIDKYISENLKGIRESIKHATEGKNVLMVAPTGSG
                     KTYSIINMLKELDTKALFIFPNSANVQQAIVEYNIAGAYDKIPTKHALEESNLVAMTW
                     DKTEQLLKEDLSEYIIVIDEIHQTYTDAFRSKAIKSLNNIINKCRGRLDITATPSKLE
                     FEIYNKVIEYKQNIQTEYKVKLYDKINIGKVIEILNNSNNAMLLKDSISTLNYISKKV
                     NKNSGVVISDTKDTSKLYDRIVSHSDMEGYEVLLNTSVIVAGVNINNPNITDIVIIGE
                     KDIGKIKQYVARARGAKSINVHIFNSYKTTNEDSNVYSVEWCINENIKDVESLTNIYN
                     KASKRDLPFKAIGIDISPINIKNIDSNIYYDKKDMCYKTDKLYIKSNAYNNYYQTRTI
                     DSFKVLLEEYFNKIEIVETEKEAKNIEEEIKKHEEAIKEFKKSAIEELEGHKKYLVGY
                     SEIKKSMTSSNLLKYHHDMRIDNNICLKHYMEHDLYSLIINNNCRKTIDLFSDFVLDN
                     SYSIDLAWKLSTYSDEKRNLVFAQINTTIYREIKEKHANSLINDDNIGTYTYNYINSM
                     FGVGTSYTKEHLEALSVDLQTFLATKKKLSIKKISLILQSIFVIEVKQHRGVTGLPYK
                     YYKNILPNPVTDKKVIRVYTIKKHIDVEDIKKELGLMDSDLSIEHLVEARINKLLNTV
                     DETEKEILLEGLV"
     gene            complement(5078..5380)
                     /locus_tag="PC494_003380"
     CDS             complement(5078..5380)
                     /locus_tag="PC494_003380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3913834.1"
                     /translation="MIKDDLLRAGFDTYGVNLEDKLLENDEIYLNDKKESERIMNRLL
                     EILEEKEHKKMLIDFEEKVFGNSVIEKEYAYRMGVLDGLDLAEFINLTKKLCLKRN"
     gene            complement(5464..5676)
                     /locus_tag="PC494_003381"
     CDS             complement(5464..5676)
                     /locus_tag="PC494_003381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF3913835.1"
                     /translation="MLKISRTNKRITQRQLSKMTNISQSYISKLERECFYHSPTIKLI
                     IELTKALEVDVLELTKYFIEKEILKT"
     gene            5824..6021
                     /locus_tag="PC494_003382"
     CDS             5824..6021
                     /locus_tag="PC494_003382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF3913836.1"
                     /translation="MYIQLNELLMSRGKSKYWLSKQTGMTPQNIGRLASNQTTSIKFD
                     SLEKICMALKCSPNELLGWDK"
     gene            6101..6646
                     /locus_tag="PC494_003383"
     CDS             6101..6646
                     /locus_tag="PC494_003383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011572951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3913837.1"
                     /translation="MDRYTFDSLPIREQIQYINNKLLEGNTLTNTCKDIGIGRTTIRN
                     RFKQHGYEFNQAKKLYISIVEVIELESSSKVVTGDTSNDNTLVDATNIDFNNILSKFN
                     DMNNKLNEVYIWYESQSSNKVVGADKLKINDFKGNTVTRSYKVYEDIQKEFAAFCEAN
                     KKYRVQDIISQALKDFMDKYK"
     gene            complement(6829..7029)
                     /locus_tag="PC494_003384"
     CDS             complement(6829..7029)
                     /locus_tag="PC494_003384"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3913838.1"
                     /translation="MNIQVYESECGNYIFKKSDESFLIDIFDKNGTHMGAFGMPSIKT
                     NTICGEKGKFISACDAWLSNLK"
     gene            complement(7187..7480)
                     /locus_tag="PC494_003385"
     CDS             complement(7187..7480)
                     /locus_tag="PC494_003385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016056424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HDF3913839.1"
                     /translation="MAREFSRSFYNSKAWKECRQSIIKKYLGLCAECGKLGEEVHHIK
                     YLTPANIHDVEITLGEENLILLCKDCHSKKHKSKKDITRTGLKFNEKGELISI"
     gene            complement(7480..7695)
                     /locus_tag="PC494_003386"
     CDS             complement(7480..7695)
                     /locus_tag="PC494_003386"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3913840.1"
                     /translation="MKKIELDDKEIKLIISALDLKVSRNLGKAYKNFPYAFDEKEEYK
                     RDVATMELLIDKFLSKLNEVECEGVLI"
BASE COUNT         2378 a         1325 c          880 g         3299 t
ORIGIN      
        1 aaaaaaaata ctactctatt tattatcttt aaagccctct aactaaatta gaaggctttt
       61 ttatttattc agcatcttgt ggagtttttg aatactctat tagtgttata ttcttctcat
      121 tcatcactgc aaagtcaaca aaaccataaa ctctaaaata tactgaacca tctgtaaagc
      181 ccatttctct tgatgtttct attcttatac tgttttgaag tcccattaat atagaatttc
      241 tatcaaatac tatagcttga ttatctttta tttgattcga agttgtcttt tcaatctgtt
      301 caactacctt aggttcattc agtggttgtc ctgttgtatc aactaataag tttaaatctg
      361 tttcagtatt agaattatat agtatatccg tagcttctcc attggctttt tttataagac
      421 caattccttt tactaaccca ttatactttg atgtagatat taaactttca tttactttat
      481 ttattcctgt atatgtcaat atcccttttg gttcattttc tccgacccca taaagtccag
      541 ctttatctat tgcacttgca atagattctg ctatagcatt tgatataatt gcatctatat
      601 taccagcact ttctaatagt tcaagtgaga ttttcatata tccatatact gttttggttc
      661 ttagctctat cccttcaaat tccatatctg attgagttgc aacttcaagc tcttttttaa
      721 agctaaattt ggggtcactt ttaactttag ctaaggttaa attattcgtt tccattggta
      781 taacattaat gtttgataaa gccattttat tcctagctaa gtcaattatt tcagctgaca
      841 actcacgtgg tataagtgtt gaacctgtac tagtattcaa agccttataa gcttccattt
      901 caacattagc gtccttccag tcacctatgt gcataccttt tatatatttt cctaaactta
      961 aattttgaga attatttata tttaaagaac ttctaaagct atctttttta cctaatgctc
     1021 taattttatt accttcccta gctgtataag aatacagatt atttttttca attggttgcg
     1081 atgtaacact atatgacgtt tctccatttg ataaacttat acttccgtta ttaaacatca
     1141 tatctgctat tattgggtca attttattat tatcctctaa tgctcttaga ttcgctcgag
     1201 cttttacttc cgtttcaaat gaactatcta aattttttat tttattagta acttcttcag
     1261 cttcttccat tttttcatca tcaagcaact tttgtgcttg gtctattagt ttttgtcttt
     1321 cttcaaaata ttcttcttta gtcacttaaa cacccctatt catcaaaact ttaatttatt
     1381 tattaagctt tttagtttct gcaattgcat cccttatatc atctcttctt aaaagttcat
     1441 cttttatcat tgaaataatt tcacttgaaa atatgtcatt tttatattct tcaaacattt
     1501 tttctaattc ttcttctgtc tttgactcta aatccaattc taaactagtt tcaaattcta
     1561 aatctttttt aaaattagtt tcaaattttt ttcttaattc ttttgtatct gtaatcaatc
     1621 tttgttttgc atacccaact aaataatcga taccaaagtc taaagacaca ttagtcttat
     1681 tgatctcatt cgcacattca gctaatttta atactattgt ctttttctca tcatctgtag
     1741 aatatacatt ttgtggatta ggaattaata attcaaagcc tccacttctt tgcttcctta
     1801 ttcgttcaca cttttcttca attgctctac acataaattc agattgactc atatttccat
     1861 cagggtctaa ttccttatag tagttcaatt tatcaattaa actttcctca acccttattg
     1921 ttattgtttt tgttttcatt acaatttcct ccttttattt ttaatataaa aataggataa
     1981 catattgtat ttcactttgc aatacattta tacattactt tgcaatacat aaatatttta
     2041 acaacaataa aagaacttca aaagtaatta tactatcgaa gttcttttat aatatatatt
     2101 gttttttagt ttcttaactc ttgtaagtgt aattagttaa ttaaactaat ccttccaata
     2161 aaatctcttt ttcagtttca tcaactgtat ttaatagctt atttattcta gcttcaacta
     2221 agtgctctat gcttaaatca ctatccatta atcctagttc ttttttaata tcctctacat
     2281 ctatatgttt cttaatagta taaactctaa tcactttttt atctgtcaca gggtttggaa
     2341 gtatattttt atagtattta tagggcaacc ctgtgacacc cctgtgttgt ttgacttcaa
     2401 taacaaaaat tgattgtaat attaagctta ttttcttaat agacagcttt ttcttagtag
     2461 ctagaaacgt ctgtaaatca acgcttaggg cttctaagtg ttcttttgtg tagcttgtgc
     2521 caactccaaa cattgaatta atatagttat aagtgtaagt cccaatatta tcatcattta
     2581 tcaaagaatt tgcatgtttt tctttaattt ctctgtaaat tgttgtattt atctgtgcaa
     2641 aaactagatt tcttttctcg tccgaatacg ttgaaagttt ccatgcaagg tcaatactat
     2701 aactattatc taatacaaaa tcactaaata agtctattgt ttttctgcaa ttattattta
     2761 ttattaggct atacaaatca tgttccatat aatgctttaa acagatatta ttatctatcc
     2821 tcatgtcatg atgatatttt aataagttac tgctggtcat tgacttctta atttcactat
     2881 agcctaccaa atacttctta tgtccctcta gttcctctat agctgatttt ttaaattcct
     2941 taatagcttc ctcatgcttc ttgatttctt cttctatgtt tttagcttct ttttcagttt
     3001 ctactatctc aattttatta aaatattcct ctaatagcac tttgaagcta tctattgttc
     3061 ttgtttggta gtaattatta taagcattac tttttatata taacttgtcc gttttatagc
     3121 acatatcttt tttatcatag tatatgttac tatcaatgtt ttttatgttt atagggctta
     3181 tatcaattcc tattgcttta aatggtaagt ccctcttaga agctttattg tatatatttg
     3241 ttaggctctc aacgtctttt atgttctcat ttatacacca ttcaaccgaa tatacattgc
     3301 tatcctcatt tgtcgttttg taactattaa aaatatgtac atttatactt tttgcccctc
     3361 tagctcttgc aacatactgt tttatttttc ctatatcttt ttcccctatt atgactatat
     3421 ctgttatgtt cggattattt atatttacac ctgcaactat cacagaagtg ttcaaaagca
     3481 cctcatagcc ttccatatca gaatgactaa caattctatc atatagttta ctagtgtctt
     3541 tagtatctga aataacaact ccactatttt tattaacttt ctttgatata taattaagtg
     3601 ttgatatact atcttttaaa agcattgcat tatttgaatt atttagtatc tctattactt
     3661 tcccaatatt gattttatcg tataacttaa ctttgtattc tgtttgtata ttttgtttat
     3721 attcaataac tttgttatat atctcaaatt ctaatttaga gggtgttgca gttatatcta
     3781 gtctacctct gcacttatta attatattat ttaagctctt tattgcttta cttctgaacg
     3841 catctgtgta agtctgatgt atttcatcaa taactattat gtactcgctt aaatcctctt
     3901 ttagaagttg ttcggtttta tcccaggtca tagccactaa attactttct tctaaagcgt
     3961 gtttagtagg tatcttatca tatgcaccag ctatattata ttcgactatt gcttgttgta
     4021 catttgccga gttggggaat ataaaaagtg cttttgtgtc tagctctttt aacatgttta
     4081 taattgagta tgtttttcca cttcctgtag gagctaccat taatacgttc ttaccttctg
     4141 tagcatgttt aattgactct ctaatacctt ttagattttc acttatgtat ttatctatat
     4201 taattatcga atcagcttta taacttgaat agttttgttt ttctagcatg gattttattt
     4261 taatattgtt atctaaataa tactttcttt tgtccttatc agtcatacac tcaaattcaa
     4321 aagctaactc aatatcattg tttttaaaag cttcttgttt cttttcttct atgaagctat
     4381 ttatatcttt tttctttatg taaatgtttt taatagtatt atttgttttt ttagtatttg
     4441 tcttactctt gttaattggc aatgagatat tatatttgtt ggctaagaat agtatagctt
     4501 caataggctt ttcaaagtgt tcatatgtac gacataactc aattatgtct gcaccaacaa
     4561 cacacccatg actatagcat gtatatattc ttttgtttaa atcaaattga aagtttttat
     4621 ccttaccacc atgaaccgga caagggacat tccctttttg agttgtatcg actcctatat
     4681 ctcttaaata tagttcatct atattggcat tttttattat atcaattaat tgttttatat
     4741 ctattttcat ttgtaaaaat cccccttttt tagttagggg ctaatcaagt tttatcaagc
     4801 tatgtattta cattctgccg taaatctcgt ataattaaca tataaaagaa taaggaaata
     4861 tatattttat atgttaatta agcctaagtg attagctcct agtattaacc cctagtggct
     4921 aactcctaat cttgattaac ccttaaatgg aaagaatgag tggatgccgt caaacaaata
     4981 ctcgttcttt ttcgtttttt tgttattagt attatatcat taataaaatt ataattcatt
     5041 gtttgaagtt attttttgac ggttttaata tatattttta atttcttttc aagcataatt
     5101 ttttagttaa gtttataaat tcagctaggt caagcccatc taaaaccccc attcggtatg
     5161 cgtattcttt ttcaattaca ctgttaccaa atactttttc ctcaaaatca attagcattt
     5221 ttttatgttc tttttcttcc aatatttcta acaatctgtt cattattctt tcagattctt
     5281 ttttgtcatt taaatatatt tcgtcatttt ctagtagttt atcttctaaa tttactccgt
     5341 atgtgtcaaa tccagccctt aataaatcat cttttatcac ttttaactct cctttttatc
     5401 tacatttaaa ccttttgcac cctattgttt gttttgtaat cttgtatttt tagttaagtt
     5461 tcgttaggtt tttaatatct ctttttcaat aaaatatttt gttaactcta acacatcaac
     5521 ttcaagtgct tttgttagtt caattatcag ctttattgtt ggactatgat aaaaacattc
     5581 tctctctaat tttgatatat aactttggct tatattggtc attttactta gttgtctttg
     5641 agttatcctt ttatttgtac gagatatttt taatatattt tctattttta atcactccca
     5701 gtattttaca cttatactat aatattaact atgcacgata atggttgtca atagttaaat
     5761 tgcgtacaat acatatcttg tgtaatatgt atttatataa ctaatgatta taagggggtt
     5821 aatatgtata tacaattaaa tgaattatta atgtctaggg gtaaaagtaa atattggtta
     5881 tcaaagcaaa caggaatgac acctcaaaac attggtcgat tagcttcaaa tcaaaccaca
     5941 tctattaaat tcgattcttt agaaaaaatt tgtatggctc ttaaatgttc acctaatgaa
     6001 ttgttaggtt gggacaaata aaaatattaa ttctaaaggg tttatttata actactagaa
     6061 aactacttta gtagttattt tattttggag gtttacacat atggatagat atacatttga
     6121 tagcttacct attagggagc aaatacaata tattaataat aagcttctag agggcaatac
     6181 attaactaac acatgcaaag atattggtat tggtcgtaca actataagaa atagatttaa
     6241 acaacatgga tatgaattta atcaagctaa gaagctatac atatctattg ttgaagttat
     6301 tgaattagaa agtagttcaa aagtagttac gggcgacact agcaatgaca atactttagt
     6361 tgacgcaact aacattgatt ttaataatat tttatctaaa ttcaatgata tgaataataa
     6421 actaaatgaa gtatatattt ggtacgaatc acaaagtagt aataaagtag ttggggctga
     6481 taaactaaaa ataaatgatt ttaagggtaa tacagtcact agaagctaca aggtatatga
     6541 agatattcaa aaagagtttg cagccttctg tgaagctaat aagaagtaca gggtacaaga
     6601 tattattagc caagctctta aagattttat ggataaatat aagtaacaac ataactactc
     6661 ctaaaattga cgtttaggga atagttaaac atatttcagc attttcaacc tttccctaaa
     6721 cttctatttt gaaactttaa aatataaagt tttagtgttt tttattttat taactattaa
     6781 acacctaaca aacttaaaaa ctttgattat ttctagtttt tattattttt actttaaatt
     6841 tgataaccaa gcatcacatg cacttatgaa ttttcccttt tctccacaaa ttgtatttgt
     6901 cttaatactg ggcatcccaa acgctcccat atgtgttcca tttttatcaa atatatctat
     6961 taaaaaactt tcatcagatt ttttaaatat ataatttcca cattcacttt cataaacttg
     7021 aatattcatt ttaataactc cttttccttt ttaatgttcg taaatcattt taaataaccc
     7081 ccctcccatt ctgatttttt catgtggagg aaaattgatg tggggacatc ggtatttgaa
     7141 atcagccccc agggtcgttt ttaagggggg gatatactat ttttttctaa atcgaaatca
     7201 attccccttt ttcattaaat tttaaccctg ttctagtaat gtctttctta ctcttatgtt
     7261 ttttactatg acagtcttta catagcaata ttaaattctc ctcacctaaa gttatctcaa
     7321 catcatgtat attagcagga gttaaatatt ttatatgatg aacttcttct cctagcttcc
     7381 cacactcagc acacaagcct agatatttct taataattga ttgcctacac tccttccaag
     7441 ctttgctatt ataaaagctt cgactaaact ctctagccat tatataagca ctccctcaca
     7501 ctctacctca ttaagcttac ttaaaaactt atcaatcaaa agctccatag ttgccacatc
     7561 cctcttatac tcttcttttt catcaaaagc atatgggaag tttttataag ctttgcctaa
     7621 gttgcgagaa acttttaaat ctaatgctga aataatcagt ttaatctctt tatcatccaa
     7681 ctctattttc ttcataaaac acctcttttt ctatacgaac attattaaaa actaattaaa
     7741 tatagttcgt atttcttcat ttgaacgtct tattttctta gagaaccaga tattcaactt
     7801 aaatttttcc tacattatat gcactgaatt tgacccctcg aatgttacta caccaaattt
     7861 ttagacattc aaataaataa at
//
LOCUS       DAMKNB010000127         7875 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.133, whole genome shotgun sequence.
ACCESSION   DAMKNB010000127 DAMKNB010000000
VERSION     DAMKNB010000127.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7875)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7875)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7875
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.133"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     misc_binding    111..322
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            485..1774
                     /locus_tag="PC494_003387"
     CDS             485..1774
                     /locus_tag="PC494_003387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytosine permease"
                     /protein_id="HDF3913841.1"
                     /translation="MEEEKINYALEQIPENQKRGWVAMFSVLVAIGVDLSSVILGAEL
                     AQSMPMKQAILSVIVGSFFSAILYTTCSLVGSSTSLSTSMITKYVFGEAGAKIFSLVI
                     GVSLLGWFGVQVGFFAQNAQIIIKDIFNLDVSMQILSLIGGLLMMSTAIYGYKAMEKL
                     SVYSVPFLLVLMMLTIFLAFRANGISVDDNMKSTMTFAGGVSLSMSIIIVGAIVSPDI
                     SRWAKSRRDCALSSFLGIQFGNAFMIIVSIVLVKCMGTSDIMRIFITLGIAIPGIIVL
                     TLAQWTTNTSNVYSASLSIALVLKKAPEKVLTIVLGIIATLLAVFGIYEGFIGFLNLL
                     GIVIAPVGGVYTAEYYIVKQELKGFDKGVLYKPIVKRSIVSWIIGILITYLSTYGFIT
                     LTTIAPLDGFIAGFVVQSIIGKVLCSTKNKQEIDKAV"
     gene            1828..2907
                     /locus_tag="PC494_003388"
     CDS             1828..2907
                     /locus_tag="PC494_003388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF917 domain-containing protein"
                     /protein_id="HDF3913842.1"
                     /translation="MRFLTEESVDKIAVGAAVLGTGGGGDPYVGKLVAKQAIKKYGPV
                     KVISLDELDDDALVVPVSGMGSPVITIEKLLSEVELTTPLEIMEKLLNRKVDVIIPIE
                     IGGINSLMPIAVAAKKGLPILDADSMGRAFPEAQMVTFYLEGYEASPAVMSDEKGNSA
                     ILYPVDGIWSERLARTLTVEMGGSSSISDYNLSGAQVKKAAIGNTLTIAETIGGFLLE
                     NKSDSKGAVENILKELCGYKLFEGKVIDIKRELKGGFTRGHAFFAGINEYDGEYSILF
                     QNENLIAKKGDTPLCITPDLIAVLDLETGFPITTERIKYGSRVMVVAFPCNEKWRTEK
                     GIETVGPGYFGYDVEYKTVEELQGK"
     gene            2928..4472
                     /locus_tag="PC494_003389"
     CDS             2928..4472
                     /locus_tag="PC494_003389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020246462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydantoinase/oxoprolinase family protein"
                     /protein_id="HDF3913843.1"
                     /translation="MYRVGIDVGGTNTDACILDGELKVIHSVKVATTKDVETGVYNAL
                     KKVIDESKIDHSLIKYAMLGTTHCTNAIVERKRLNNVAMIRIGKPATTAILPFIDWPE
                     DLREKIELDSILVSGGYEFDGRKINELCKDEVVEFCNRIKGKVESVAISGVFAPVNKQ
                     QEEEVAKWVREILGDIPISLSNEIGNIGILERENGAILNSALSQVGKAVSLGFEKALK
                     DLGIDAQIYFSQNDGTLMNLEYTMKYPIFTIGCGITNSIRGASFLSKVKNAIVLDVGG
                     TTSDLGVLYNGFPRESSIPVTIGGVHTNFRMPDVLTIGLAGGTCVKGEKDNIKIGPES
                     VGYRITEDAIIFGGDTLTLSDVVTKLDMAFEDRKSNVENLDKEYCNEVYKKVILKLED
                     AVDQMKTSQDDVELVLTGGGSIIVPEKLKGISNVIRPPHYTAANAIGAALGQISGDVE
                     KVYSLDKMSREDAIEDAKKEAVNKALKAGAKEDTIEVLNIEDVPLAYLPGNALLIKVK
                     VVGDLI"
     gene            complement(4635..5177)
                     /locus_tag="PC494_003390"
     CDS             complement(4635..5177)
                     /locus_tag="PC494_003390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1697 domain-containing protein"
                     /protein_id="HDF3913844.1"
                     /translation="MKSYIALLRGINISGKNKIIMSELKASFVELGYSEVSTYLNSGN
                     VVFLSDVDDSKVISNTIRLMIKKQFELEIPVFIISQEELKDILNNAPNWWGDNNKEIY
                     DNLIFMFPDLSYDEFYDEVGNPKEEYEKVYHYKNAIFWSFSRKDYKKTNWWSKTASSN
                     VSDKITIRTANTVRKIVGMR"
     gene            complement(5325..5609)
                     /locus_tag="PC494_003391"
     CDS             complement(5325..5609)
                     /locus_tag="PC494_003391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HDF3913845.1"
                     /translation="MAKNTKQTTVHIDETLLKEVKRIGINENKSISQIINESIIDYIL
                     VYRENEDKEKNEHDKNLNETINEFKKEEEKRMQAKSAARAIAEAKKRVLY"
     gene            complement(5672..6436)
                     /locus_tag="PC494_003392"
     CDS             complement(5672..6436)
                     /locus_tag="PC494_003392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HDF3913846.1"
                     /translation="MNNYLKFATYQLIGFTSSIPRLIKIKKNPDKFSLKEKFEFMQKQ
                     AKKSLDIVNIELNIIGKETLPKEPLLFVVNHSSMLDSFILTASVERPIGCVIADEPVW
                     RNIPIFKEWAKLLRCVYVNRKNNREGIKSIAQASQNILTGQSMAVFPEGDLTWIKEPN
                     SLVSEFRSGALKIAYKAKCPIVPLVIKNSKDTYEGYQPIGKINSVPVEVEFLEPIYDH
                     IENPRLKSSVLGENIKNKMINTIENFRKSNKTFKEF"
     gene            complement(6718..6984)
                     /locus_tag="PC494_003393"
     CDS             complement(6718..6984)
                     /locus_tag="PC494_003393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3795 domain-containing protein"
                     /protein_id="HDF3913847.1"
                     /translation="MIESRCGILCYECGYKEKVNCKGCTEIEKPFWGEQCPVKSCCED
                     KNLTHCGLCDTFPCEMLNQFAYDKEQGDDGKRISQCKKWAVLAL"
     gene            complement(7026..7835)
                     /locus_tag="PC494_003394"
     CDS             complement(7026..7835)
                     /locus_tag="PC494_003394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF3913848.1"
                     /translation="MNKIINNILNTCKQYTYILPHKLLRQYIAHYTISIPDTSIKENL
                     TLIPDASGCMIFKFDKKGIESAFWGATTKTTIVKNDIENVLFRVFVEFRPGGVYYLTG
                     LSQRESTDLKISLEDFNTLFSLEVNSIFERTSTIKELVEQLDMLFLSYLLKSNIVDMT
                     IPILENARKQNSIMSVKNISQISCYSERHLNRIFNNSLGMSVKSYLRLLRINLVLQEI
                     QNNKIPFATLAQDIGYYDQSHFINDFKSICGVNPTTYIKNLSDFYNEKYKF"
BASE COUNT         2747 a         1000 c         1284 g         2844 t
ORIGIN      
        1 atgaaaattt acatataaaa ctaaaaaatg caagtaattg actttttaag ttgacaaaat
       61 attgcatata tattatgata taaatcataa attaactaca aatcaatatt atatattcgt
      121 agaagaagaa agtagcataa aggaatttta cagagagtta gatttggctg agaactaata
      181 ttggaattta tgtgaaaagg actttggaga atactattgt aattatgtta gaatagtggt
      241 ttaattcgcc ttaagaaaat gagtgagtaa aattaatttt tactaataag agtggtaaca
      301 cggatttata ttcgtctctt ggatttttcc aagaggcgtt ttttattata aacttatttc
      361 agaaaattta aaactatata ttaaatgaaa attataaaaa tatgatagtt aataaattta
      421 taaattagaa aattgtaaaa tatgctaagg tcagtagttt tacgatttaa atggagggat
      481 gaaaatggaa gaagaaaaaa ttaactatgc tctggaacag attccagaga atcaaaaacg
      541 tggttgggta gctatgtttt cagttttagt agcaataggt gtggatttat catctgttat
      601 tttaggcgct gagttggcac agagtatgcc aatgaaacaa gcaatattgt cagtaattgt
      661 tggttcattt ttttctgcaa ttttgtatac tacatgctct ttggttggtt catctacaag
      721 tttatctaca tctatgataa caaagtatgt atttggagaa gctggagcaa aaatattttc
      781 tctagttata ggggtttctc tattaggttg gtttggagtt caagtaggtt tctttgctca
      841 aaatgcacag ataataataa aagatatatt taatttagat gtcagtatgc agattttaag
      901 cctaataggt ggtctcttga tgatgagtac tgcaatttat ggatataagg caatggagaa
      961 gttgagtgtg tattcagtac catttttatt agttcttatg atgctaacta tattcttagc
     1021 ttttagagca aatggaattt cagttgatga taatatgaaa tctactatga catttgcagg
     1081 tggagtttct ctgtcaatga gtataataat agttggtgca attgtatctc ctgatataag
     1141 tcgttgggct aaaagtagaa gagactgtgc tctttcaagc tttttgggaa tacaatttgg
     1201 aaatgctttt atgataatag tttcgatagt attagtaaaa tgtatgggaa cttcagatat
     1261 tatgagaatt tttattacat taggaattgc tataccaggt ataatagtac ttacattagc
     1321 acaatggact acaaatacaa gtaatgtata ttcagcatca ttaagtatag ctcttgtact
     1381 taagaaggct cctgagaaag tattaactat agtccttggt attatagcaa cattattggc
     1441 tgtatttgga atatatgaag gttttatagg atttttaaat ttacttggaa ttgtaattgc
     1501 acctgttggt ggtgtatata cagcagaata ttacatagta aagcaagaac ttaaaggctt
     1561 tgataaagga gtattatata aaccaatagt taaacgttca atagtgtctt ggataattgg
     1621 tatattaata acttaccttt caacatatgg atttataact cttactacta tagcaccttt
     1681 agatggtttt atagcagggt ttgtagtaca atctattatt ggaaaagtgc tttgttcaac
     1741 aaaaaataag caagaaatag acaaagcagt ataaagaaat ttgtttataa agtataaaat
     1801 aaattagaaa tatgaggaga aagtaacatg agatttttaa cagaagaaag tgtagataaa
     1861 atagcagttg gtgcagcagt gcttggaact ggaggtggag gtgacccata tgtaggtaaa
     1921 ttggttgcaa aacaagccat taaaaagtat ggtcctgtaa aagtaataag tttagatgaa
     1981 cttgatgatg atgctttggt agttccagta tctggtatgg gttctcctgt aattacaata
     2041 gaaaaattac tttcagaagt agagttaact acccctttag aaataatgga gaaattatta
     2101 aatagaaaag tggatgttat aattcctata gaaataggag ggataaactc acttatgcct
     2161 atagcagttg ctgctaaaaa aggacttcct atcttagatg cagattctat gggtagagct
     2221 ttccctgaag ctcaaatggt aactttttat cttgaaggat atgaggcatc tcctgccgta
     2281 atgtctgatg aaaaaggtaa ttctgccatc ctttatcctg tggatggaat ttggtcagaa
     2341 agattagcta gaactttaac tgtagaaatg ggaggaagtt cttctattag tgactataat
     2401 ttaagtggag ctcaagttaa aaaagctgct ataggtaata ctcttacaat agctgaaact
     2461 ataggagggt ttttacttga aaataaatct gattcaaaag gtgctgttga gaatatacta
     2521 aaagaattgt gtggatacaa gttatttgaa ggaaaagtaa ttgatattaa gagagagttg
     2581 aaaggtggat ttactagagg acatgccttt tttgctggga ttaatgagta tgatggagag
     2641 tattctatat tattccaaaa tgagaattta attgccaaaa aaggtgatac accactttgt
     2701 attacaccag atttaatagc agtattagat ttagaaactg gatttccaat aactacagag
     2761 agaataaaat atggctctcg tgttatggta gtagcttttc cttgtaatga aaaatggaga
     2821 acagaaaaag gaattgagac agttggacct ggatactttg gatatgatgt ggaatataaa
     2881 acagtagaag aattacaagg aaaataaaag tttaggagga aattttgatg tatcgtgtag
     2941 gaattgacgt tggaggaaca aatacagatg cttgtatact ggatggggaa ttaaaagtaa
     3001 ttcattcagt taaggtggca actacaaaag atgttgaaac tggtgtttac aatgccttaa
     3061 aaaaagttat agatgaaagt aagattgacc attcattaat aaaatatgct atgcttggta
     3121 caactcattg tacaaatgct attgtagaaa gaaaaagact taataatgtg gctatgataa
     3181 gaataggaaa gccggccact actgccattc ttccatttat agattggcca gaagacttaa
     3241 gagaaaaaat agaattagat tcaatattgg tatctggtgg atatgagttt gatggcagaa
     3301 aaataaatga actttgtaaa gatgaagttg tagagttttg caatagaata aaaggcaaag
     3361 tggaaagtgt tgcaataagt ggagtatttg ctccagtaaa taaacaacaa gaagaagaag
     3421 ttgcaaaatg ggttagagaa attttagggg atattcctat atctttatca aatgaaatag
     3481 gtaatatagg tatattagaa agagaaaatg gagctatttt aaattctgca ttgtctcaag
     3541 taggtaaagc tgtatcttta ggatttgaaa aagcacttaa agatttaggt atagatgctc
     3601 aaatatattt cagtcaaaat gatggaacat taatgaattt agagtataca atgaaatacc
     3661 caatttttac aattggatgt ggaataacaa attctataag aggagcttcc ttcttatcaa
     3721 aagtaaaaaa tgcaatagta ttagatgttg gtggaactac aagcgacttg ggtgtactat
     3781 ataatggatt ccctagagaa tcatctattc cagttacaat tggaggagta catacaaact
     3841 ttagaatgcc agatgtttta actattggtc ttgctggtgg tacatgtgta aaaggcgaaa
     3901 aagataatat aaagataggt cctgaaagtg tgggatatag aataactgaa gatgcaataa
     3961 tatttggtgg agacactcta actttatcag atgttgttac aaaattagat atggcgtttg
     4021 aagatagaaa aagcaatgtt gaaaacttag ataaagagta ttgtaatgag gtatataaga
     4081 aggttatttt aaaattagaa gatgctgtag accaaatgaa gactagtcaa gatgatgttg
     4141 aattggtttt aactggtgga ggaagtataa ttgttcctga aaaactaaaa ggcataagca
     4201 atgttataag acctcctcat tatactgctg caaatgctat tggtgcagct ttaggacaaa
     4261 taagtggaga tgtagaaaaa gtatacagtt tagataaaat gtcgagagaa gatgccatag
     4321 aagatgcaaa aaaagaggct gtaaataaag ctctaaaagc tggtgctaaa gaagatacta
     4381 tagaagtatt aaatatagaa gatgttccac ttgcatacct tcctggtaat gcacttctta
     4441 taaaagtaaa agttgttggt gatttaattt aaagaataaa tataagtatt tccagaatta
     4501 tataaatatt tctggactca tttttaaact tattttatca ataaaaacag cataactttt
     4561 gactatattc ttataagttt ccgaacagcc gatatatacc tattttttga ggtttatcgg
     4621 ctgtttgtta tcttttatcg cattccaact atttttctta ccgtatttgc tgtacgaatt
     4681 gtaatcttat cacttacatt tgaactggca gtctttgacc accaatttgt ctttttataa
     4741 tctttacgac taaaagacca aaagatagca tttttataat gatatacttt ttcatactct
     4801 tctttaggat ttccaacctc atcataaaac tcgtcataag ataagtcagg aaacataaaa
     4861 ataagattat catatatttc tttgttgtta tctccccacc aattaggagc attatttagt
     4921 atatctttta actcttcttg tgaaataata aaaactggta tttccaattc aaactgtttt
     4981 tttatcatta atcttattgt atttgagata accttgctgt catctacatc acttaaaaag
     5041 acaacattac cactattaag gtatgtagaa acttctgaat aaccaagttc tacaaagctt
     5101 gcttttaatt cagacataat tatcttgttc ttaccactta tattgatacc tcttaataat
     5161 gcgatataac ttttcatata ataatttcac ctctaaacat tcacattttt ctatgtagta
     5221 caaacttgaa tttgcatctt ttataattct ttcaaaactt cttcatatgt aattttttta
     5281 atataaaaaa atcggtgctt aatttgtacc gatttttgtt tttcctagta aagaactcgt
     5341 ttttttgctt ctgctatagc tctagcagca ctttttgctt gcattctttt ttcttcttct
     5401 tttttaaatt catttattgt ttcatttaga ttcttatcat gttcattttt ttctttatct
     5461 tcgttttctc tgtatactaa tatataatct attattgatt cgtttattat ctgagatata
     5521 cttttatttt cattaattcc tattctctta acttccttaa gtagagtctc atcaatatga
     5581 accgttgttt gctttgtatt ttttgccacc ttaatcacct cttaaaaaaa attctaacat
     5641 taaaattttt tttagtcaat aaattttaat attaaaattc tttaaatgtt ttatttgatt
     5701 ttctaaaatt ttctattgta tttatcatct tattttttat attttcacct agtacagaag
     5761 actttagtct aggattttcg atatggtcat aaattggttc taaaaattca acttcgacag
     5821 gaacagagtt aattttacca ataggttggt atccttcata agtatctttt gaatttttta
     5881 ttacgagtgg aacaataggg cattttgctt tatatgctat ctttaaagct ccacttctaa
     5941 actccgaaac caatgaattt ggttctttaa tccatgttaa atctccttct ggaaacactg
     6001 ccatactttg acctgtaagt atattttgag aggcttgggc tatactcttt ataccctcac
     6061 gattgttttt tctgtttaca tatacacatc ttagtaattt tgcccattct ttaaatatag
     6121 gtatatttct ccaaactggt tcatctgcaa ttacacatcc aattggtctt tctacacttg
     6181 ctgttagtat gaagctgtca agcatactag aatgatttac aacaaataga agtggttctt
     6241 ttggcagtgt ttccttacca attatattaa gctctatatt cactatatct aaagattttt
     6301 tagcttgttt ttgcataaat tcaaattttt cctttaagct aaatttatca ggattctttt
     6361 taattttaat aagcctaggt atagaagatg taaaacctat aagttgatat gtagcaaatt
     6421 ttaagtaatt attcataaaa ttatctcctt aaaataaaat tatttattac tgtaaagatt
     6481 ttaacataaa ataaaattta agtctatttt aattcaattt tgtaacatat attttaaata
     6541 gacagagatt gagattttat atttccaatt ttagtaatca gattttatca ataaattact
     6601 attctattaa tttaattaaa taacctttaa atttaattat aaaaactgtt gcagaaattt
     6661 ctacaacagt ttaaaaaatt taccttacaa aaacttattt tataacaaga gagtatatta
     6721 taaggctagt acagcccatt ttttgcactg agaaattctt ttgccatcat caccttgttc
     6781 tttgtcatat gcaaattgat taagcatttc acatggaaat gtatcacata gaccacaatg
     6841 tgtaaggttt ttatcttcac aacaagattt tacaggacat tgttcacccc aaaatggttt
     6901 ctcaatctct gtacaacctt tacaattgac tttttccttg tatccacatt cataacataa
     6961 aattccacat cttgattcta tcattttaag tcactcctta aatataaatt ttatatgatt
     7021 gtatatcaaa atttatactt ttcattgtaa aaatcggaca aattttttat ataggttgtt
     7081 ggattaacac cacaaataga tttaaaatca tttataaaat gagattggtc gtaataacca
     7141 atatcttgtg ctaaagttgc aaatggtatt ttattatttt gtatttcttg taatacaagg
     7201 tttatacgaa gtaatctaag gtatgattta acactcatac caagagaatt attaaaaatt
     7261 ctatttaaat gtcgttcact ataacaacta atttgtgaaa tgtttttaac agacataata
     7321 gagttttgtt ttctagcatt ttcaagaatt ggtatagtca tatctactat atttgatttc
     7381 aataagtatg ataagaataa catatctaat tgttctacta attcctttat agtacttgtt
     7441 ctttcaaaaa tggaattaac ctctaagcta aataatgtgt taaaatcttc aagtgaaatt
     7501 tttaaatctg tagattctct ttgagaaaga cctgtcaaat aatatactcc acctgggcga
     7561 aactcaacga atactctaaa aagtacattt tctatatcat tttttacaat agtagttttt
     7621 gttgtggctc cccagaatgc gctttctata ccttttttgt caaatttaaa tatcatacat
     7681 ccactagcat caggtattaa tgtaagattt tctttaatac ttgtatctgg aatagatatt
     7741 gtatagtgtg ctatatactg tcttaacaat ttatgtggca aaatatatgt atactgtttg
     7801 caggtattta aaatgttatt gattatttta ttcataagta tatcctcctg atatataaaa
     7861 aataagtata ctaat
//
LOCUS       DAMKNB010000128         7804 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.134, whole genome shotgun sequence.
ACCESSION   DAMKNB010000128 DAMKNB010000000
VERSION     DAMKNB010000128.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7804)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7804)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7804
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.134"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            complement(237..2516)
                     /locus_tag="PC494_003395"
     CDS             complement(237..2516)
                     /locus_tag="PC494_003395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HDF3913849.1"
                     /translation="MLSDAKNNRYGLSIIAVISILVITISCLIYGSRLNKTLGEETNQ
                     YLSEIANQSVNVLKKQINGDIKLLESISIFIEGEESFEVDNILSILKRQAINSSFKRM
                     GVILPNGTAYTTDGYIEDFSKRDYFLKSMQGEVVITGKLKDVIEDDKNTNSNINVYSV
                     PIYKDNEVKGVIFATHSTKLYEKILSVPTFNGKGYSYITRSNGDIVLNPSSKNANSTK
                     ENLFSYIGRSDSISKSSINNMKSNIKNFKSGSLSYSMFGKGYYLSYAPIGINDWYLFS
                     EVPKTAISEKSYAIIKLTLSACVVLIIIFTALTIYILFIHKKSKEKLEEFAFKDNVTG
                     IGNSNKFNLEGGKFLSSHEKKNLVLIYFDIDKFKLVNDRFGYEEGDRVLKEIAEIIKN
                     IFKEQSVFSRISNDNFAIIFEKKNNRESIIEICELIRKKLSMIKTSLGVELNLIPSIG
                     VYFVEEGETNISTCLDKAMIAKTTVKRKYLKVYEIYAENLKETLIEERDIEQEMHDAL
                     KNEQFKVYLQPKVDLSTTKIVGAEALVRWQHPKKGLISPGVFIPIFEKNGFITELDMF
                     VFTQVCKNFKRWENENFPTFPISINLSRVHLENPGFISELERITKEYEIEPNLIEIEL
                     TESAIFDNTKILFKIMQTLKSVGFKISMDDFGSGYSSLNMLKDMPIDVLKLDRQFFIT
                     VGNAKKSQIVVSSIVQMAKQLDIKVVSEGVETVEQAEFLRFIGCDMAQGFLFARPMPI
                     EEYEKLILDRYSLNRKETN"
     gene            complement(2787..4241)
                     /locus_tag="PC494_003396"
     CDS             complement(2787..4241)
                     /locus_tag="PC494_003396"
                     /EC_number="6.3.2.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,
                     6-diaminopimelate ligase"
                     /protein_id="HDF3913850.1"
                     /translation="MKLNDIIQGLDIINVKGELNIDINNVQYDSRKVTKGTLFICIKG
                     FVSDGHKYIKDAIEKGASAFLVEEDVAIKGCTFIKVKDTRKDMAKVADNFYNHPSQKF
                     NVIGVTGTNGKTSITTILNEILTLNKNKVGLIGTIKIFDGEKDIVSNSTTPESIDLQY
                     HFNNMLDNGCDYCAMEVSSHSLALNRVDETDFKLGIFTNLTPDHLDFHKDLEDYRKAK
                     EKLFFKTTMANIINIDDEGGKKIYENIKGINVPCYTYGVDTKADFMARDIKSDSDGVS
                     YRLITPSYEEVIFIPVPGMFTVYNTLAVIAACYVLGIPKPIYKEGLRLSNGVSGRFET
                     VPNDKGISVIVDYAHTPDALENVLKTTQQFAEGKIISVFGCGGDRDTEKRPLMGAIGQ
                     KYSDLCIITSDNPRTEEPEAIIKDILEGIDKKKENYHVVVDREQAIAEAISMAKKDDV
                     VIITGKGHETYQIIGKVKHHFDDKEVANECLSKM"
     gene            4405..5274
                     /locus_tag="PC494_003397"
     CDS             4405..5274
                     /locus_tag="PC494_003397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF3913851.1"
                     /translation="MDNKIGYLNDNFKIFNIRDKKDIQFEYHNHDFNKIIIFINGNVT
                     YFVDGIPYKLKPWDILFISNNEIHKPVIDSNVFYERIAIWISPEFMKKNSDATSDLEK
                     CFKIATENKCNRLRLNIHDIESIKSFIEQINISESNTEFGNEILRNALFIQLMIFLNR
                     IFLKNENMESTEDVFYDETIKKVLNYINSNIDDKLSIDSISSEFFISKYYLMRKFKSH
                     TGTSIHNYIVQKRLILAKSLITNGHLMSEVCNKCGFNDYSSFVRAFKKNYGVSPKNYI
                     NNKNPLDITLLDE"
     gene            complement(5487..7559)
                     /locus_tag="PC494_003398"
     CDS             complement(5487..7559)
                     /locus_tag="PC494_003398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HDF3913852.1"
                     /translation="MKKVFGVLQKVGKSLMLPVALLPAAGILLGVSNALAGDALLAHF
                     PALANPTFQLIISIMESSGQIIFNNLPLIFAVGVAVGLTEGEGVAALAAIVGFLILNT
                     SMGVMAGVTEDMVDNSMYANIVGIPTIQTGVFGGIIIGIVAAYLYKKFYKIELPQYLG
                     FFAGKRFVPIVTSLVAIAIGIILSFIWPPIQEGLLSFSKNVIEANQTLAAFMEGSLER
                     LLIPFGLHHVFHNPFWYQFGEYVNKAGELVMGDQKIFFAQLKDGVNFTAGTFMTGAFP
                     FMMFGLPAAALAMVHEAKPEKKKFVAGIMASAALTSFLTGITEPIEFAFLFVAPVLFA
                     IHCLFSGLSYAIMQLLGVKIGFTFSGGLIDFLLFGVLPNRTPWYLAILVGIGFAVLYY
                     SVFRFMIRKFNLKTPGREDESETNAEVIEMSKNELASEILIALGNKDNLKSLDACITR
                     LRLVVNDINKVDKEKLKSLGAAGVMVIGNNVQAIFGPKSDSIKSDIKDIIEGKTKVES
                     TVTKNVDKNKVKKNMEVANMENALVEKIDSLTNGEILDIEEVPDSVFSSKLMGDGFAI
                     KSSDGLIYSPVDGTIGVIFPTKHAIIIKSQKSGVEILIHLGIETVNLEGNGFEVFVNV
                     GDEVKAGEKLVKMDLEYIEKNGLSTISPVVFTNLEQNQKLSIKKGVTTAKEENRVSIL
                     RDDIEKIG"
BASE COUNT         2651 a         1296 c          827 g         3030 t
ORIGIN      
        1 gaaattacta ttattactat ctaaagtatt ttgctataat cccatatact cttacctcaa
       61 aaacatccaa atgtaaaaaa tactacatat taataaactt tgcccaataa ttcctaaaat
      121 aatatcctaa caatgattta tgtttttata atagtatatt tttacataaa aaagtgaaca
      181 ttgattaaca aagttcactt ttttataaat ttttatgtta taattcacaa ttttatttaa
      241 tttgtttctt ttctatttaa actatatcta tctaatatta atttttcata ttcttctatt
      301 ggcattggtc tagcaaataa aaatccttgg gccatatcac aacctataaa ccttaaaaac
      361 tctgcttgct ctacagtttc aacaccttct gaaacaactt ttatatcaag ttgctttgcc
      421 atttgaacaa tacttgaaac tacaatttga ctcttttttg catttcccac tgttataaag
      481 aattgcctat ctaatttcaa tacatcaatt ggcatatctt taagcatatt taaagaagaa
      541 taaccagaac caaaatcatc catagaaatt ttaaatccaa cagatttcaa agtttgcatt
      601 attttaaata atatttttgt attgtcaaat attgcacttt ctgtcaattc aatctcaatt
      661 aaatttggtt caatttcata ttcttttgtt attctttcaa gctcagaaat aaagcctgga
      721 ttctcaagat gtactcttga taagtttatt gatataggaa atgtggggaa attttcattt
      781 tcccaacgtt taaaattttt acaaacttgg gtaaatacaa acatatccaa ttctgttata
      841 aaaccatttt tctcaaaaat aggaataaat acacctggac ttattagacc ttttttagga
      901 tgttgccaac gtacaagtgc ttcagcacct acaattttag tagttgataa atcaacctta
      961 ggctgtaaat aaactttaaa ttgttcattt tttaaagcat catgcatttc ttgttcaata
     1021 tcacgttctt ctatgagagt ttcttttaaa ttttcagcat aaatctcata aacttttaaa
     1081 tattttcttt ttactgtagt ttttgcaatc atagctttgt caagacaggt agaaatattt
     1141 gtttctccct cttcaacaaa atatacacct atggatggaa ttaaattgag ttctactccc
     1201 aaacttgttt ttatcattga caatttttta cgtataagtt cacatatttc tataattgac
     1261 tctctattat ttttcttttc aaatattata gcaaaattgt catttgaaat tcttgaaaat
     1321 acagattgct ctttaaatat attcttaatt atctctgcta tttcctttaa tactctatct
     1381 ccttcttcat acccaaacct atcatttact agcttaaact tatctatatc aaaataaatt
     1441 aaaactagat tctttttctc atgagaggat aaaaattttc ccccttcaag attaaattta
     1501 tttgaattgc caatacctgt aacgttatct ttaaaagcaa attcttccaa tttttcctta
     1561 ctctttttat gtataaatag tatataaatt gttaatgccg taaagattat aatcaagact
     1621 acacatgctg ataatgtaag ttttataata gcatatgatt tctcagatat agcagtttta
     1681 ggaacttcag aaaaaagata ccaatcattg attcctattg gggcataact taaataatat
     1741 ccttttccaa acatactata acttaatgaa cctgatttaa agttttttat atttgacttc
     1801 atattgttga tactagattt tgatattgaa tcacttctgc caatgtaaga aaataaattt
     1861 tctttagtag agttggcgtt tttactgctt ggatttaaaa caatatcacc attacttcta
     1921 gttatataag aatatccttt tccattaaat gtaggtacag aaagtatttt ttcatacaac
     1981 ttcgtactat gtgtggcaaa tataactcct ttaacctcat tatctttata aattggtaca
     2041 gaatatacat taatattact attggtattt ttatcatctt ctattacatc ttttaatttg
     2101 cctgttataa ccacttctcc ttgcattgat tttaagaaat aatctctttt agaaaagtct
     2161 tctatataac catctgtagt gtatgctgta ccatttggta aaataactcc cattctttta
     2221 aatgaactat taatagcttg cctttttagt atagaaagga tattatctac ttcaaaagac
     2281 tcttctcctt caataaatat tgaaattgac tctagtaact ttatatctcc attaatttgt
     2341 ttttttaaca cattgacgct ttgatttgct atttctgaaa gatattgatt cgtttcttca
     2401 cctaatgtct tattcaacct tgaaccataa atcaaacagg aaattgtaat tactaagata
     2461 cttatgacag caattatgga caaaccatac ctattatttt ttgcatcact taacattatg
     2521 cttcctgcct ttctcgaatc tatgtatgta taatcattat cttatgacaa ttattgtaaa
     2581 cattttataa taatacttat ttttccatat ttactgtaat tatacaaaat tataaacttt
     2641 attacaacaa taaattaatt aatatagata ttagtgttta tattattgca ttatctattt
     2701 tacaattatt tacatataaa aaaatgtaat atcaaagtga agcttgatat tacatttttg
     2761 ttcttgtatt ttgtttaatt tttatgctac atcttactta aacactcatt tgcaacttct
     2821 ttatcatcaa aatgatgctt aactttacct ataatttgat aagtttcatg tcccttacct
     2881 gttataatta caacatcatc cttttttgcc atacttatag cttctgctat agcttgttct
     2941 ctatcaacaa caacatggta attttctttt ttcttgtcaa ttccttcaag tatatctttt
     3001 attattgcct ctggttcttc agttcttgga ttatcagaag ttataataca taaatcagaa
     3061 tatttttgtc caattgctcc catcaaaggt ctcttttcag tatctctatc tccaccacac
     3121 ccaaacacag aaattatttt tccttctgca aattgttgag ttgtctttag tacattttca
     3181 agtgcgtcag gagtatgagc atagtctaca attacgctta tacctttatc atttggaact
     3241 gtttcaaacc ttcctgatac tccattagaa agtctaaggc cttctttata tattggttta
     3301 ggtatgccaa gtacatagca agcagctata actgctaaag tattatatac tgtaaacatt
     3361 cctggaactg gtataaatat tacttcttca tatgaaggtg ttattaatct ataagatact
     3421 ccatccgaat ctgattttat atctctagcc ataaaatcag ccttagtatc aacaccataa
     3481 gtgtaacaag gtacatttat accttttata ttttcatata tcttctttcc accttcatca
     3541 tctatgttta ttatatttgc catagtagtc ttaaaaaata atttttcttt tgcttttcta
     3601 taatcctcta aatctttatg aaaatctaaa tggtctggtg ttaaatttgt aaatatgcct
     3661 agtttaaagt ctgtttcatc aactctattt aatgccaatg aatgtgatga aacttccatt
     3721 gcacagtagt cacatccatt atccaacata ttattaaaat gatattgtaa atctatactt
     3781 tctggagttg ttgaattgga aacaatgtct ttttctccat caaaaatttt tatagttcct
     3841 ataagtccaa ctttattctt atttaaagtt aatatctcat ttagtatagt agttatacta
     3901 gtttttccat tagtacctgt aactcctata acgttaaatt tttgagatgg atgattgtaa
     3961 aaattatcag ctacttttgc catatctttt cttgtatctt ttacctttat aaatgtacat
     4021 ccttttattg ctacatcttc ttcaacaaga aatgcacttg ctcccttttc tatggcatct
     4081 tttatatact tatgaccatc tgacacaaat ccttttatac atataaataa tgtacctttt
     4141 gtaacctttc ttgaatcata ttgtacatta ttaatatcta tatttaattc acccttgaca
     4201 ttgattatat ccaacccctg tataatatca tttaatttca taaatgcttt cctcccttta
     4261 aactctttct gctaaaatta cactacatat aatattatat taagaatttt ttactatgtg
     4321 aatggttaaa aatgcttgaa acattgcaaa aaatgctcta taattttcta taatataact
     4381 gaggaaaggt cttctataaa aactatggat aataaaatcg ggtacttaaa cgataacttt
     4441 aaaatattta atattagaga taaaaaagat atacaatttg aataccataa tcatgatttt
     4501 aataagataa ttatatttat aaatggaaat gtaacttatt ttgttgatgg tattccctat
     4561 aaactaaagc cttgggatat actctttatc agcaataatg aaatacataa accagttata
     4621 gattcaaatg tcttttatga gagaattgca atatggatta gcccagaatt tatgaaaaaa
     4681 aatagtgatg ctactagtga cttagaaaaa tgttttaaaa tagctacaga gaataaatgc
     4741 aatagattgc gtttaaatat acatgatatt gaatctatta agagttttat tgagcaaata
     4801 aatatttccg aatccaatac tgaatttgga aatgaaatat tgagaaatgc attatttata
     4861 caacttatga tattcttaaa cagaattttc ctaaaaaatg aaaatatgga atcaacagaa
     4921 gacgtttttt atgatgaaac tattaagaaa gtattaaact atataaattc aaatatagat
     4981 gataagcttt caatagatag catatcgtct gaatttttta taagtaagta ttatcttatg
     5041 agaaaattta aatctcatac tggaacgtct atacacaatt atatagttca aaaaagatta
     5101 attttggcaa agtcactaat aaccaatggt caccttatga gtgaagtttg taataaatgt
     5161 ggattcaacg attattctag ttttgtaagg gcatttaaaa aaaactacgg tgtatctcct
     5221 aaaaattata taaacaataa aaatccttta gatattactc ttttagatga atagataatt
     5281 tatgtaaatt ttattttaat aaaacttgaa gtattagtgt atttatctta ctaatacctc
     5341 aagtttttta atgttttaaa atatatcaaa atataatgat atatatttct attacttaaa
     5401 atatatatta aataaattgc atgttaactg aacctattta tatatttatt aaatctcaca
     5461 taacttttag ttacactatc atatagctat cctatttttt caatatcatc tcttaatata
     5521 cttactctat tctcctcttt tgctgtggtt actccttttt taatgcttaa tttctgattt
     5581 tgttctaaat tcgtaaatac tacaggactt attgttgata gaccattttt ttcaatatat
     5641 tctaagtcca ttttaactaa tttttctccc gcttttactt catctcctac attcacaaat
     5701 acttcaaatc catttccttc taagtttaca gtttctatcc ctaaatgtat aagtatttct
     5761 actccacttt tttgggattt tattattatt gcatgcttag ttggaaatat aactccaata
     5821 gttccatcaa ctggtgaata aatcaatcca tcactagatt taattgcaaa tccatccccc
     5881 atcagtttac ttgaaaatac agaatctggc acttcttcta tatctaatat ctctccattt
     5941 gttaatgaat caatcttttc tactaaagca ttttccatat ttgcaacttc catatttttt
     6001 ttcactttat ttttatcaac atttttagta acagtacttt caacctttgt ttttccctct
     6061 attatatctt ttatatcaga ctttattgaa tccgattttg gtccaaatat agcttgaaca
     6121 ttgttgccaa taaccataac acctgctgct ccaagtgatt tcaatttttc tttatctact
     6181 ttatttatat catttacaac caatctaagt cttgttatac acgcatctag gctctttaaa
     6241 ttgtctttat ttcctaaagc aatcaaaatc tctgatgcta attcattctt agacatttca
     6301 atgacttcag cgttagtttc tgactcatct tctcttcctg gtgtctttaa attaaacttt
     6361 cttatcataa atctaaatac actatagtat aatactgcaa aaccaatacc taccaagata
     6421 gccaagtacc atggagttct attaggaaga acaccaaata ataagaaatc tattaatcct
     6481 cctgaaaatg tgaatccaat tttaactcct aataattgca taattgcgta tgataaacct
     6541 gaaaataaac aatgtattgc aaataatact ggtgcaacaa ataaaaacgc aaactctatt
     6601 ggctcggtta ttcctgttaa aaaagaggtt aatgctgctg atgccattat acctgctaca
     6661 aattttttct tttctggctt tgcttcatgc accatagcaa gagctgctgc tggaagacca
     6721 aacatcataa atggaaatgc acctgtcata aaagtacctg ctgtgaaatt tactccatct
     6781 ttaagttgag caaagaatat cttttggtca cccattacaa gctcaccagc tttatttaca
     6841 tattctccaa attgatacca aaatggatta tggaaaacat gatgcaaacc aaatggtatt
     6901 aatagtcttt ccaaagaacc ttccataaat gctgctagtg tttgatttgc ttctataaca
     6961 ttttttgaga aactaagtaa tccctcttgt attggaggcc aaataaaaga caatataatt
     7021 cctattgcta tagcaactaa tgaagtaacg attggtacaa atcttttacc tgcaaaaaaa
     7081 cctagatact gaggtaattc aattttataa aactttttat aaagataagc agccactatc
     7141 cctataataa taccaccaaa tacccctgtt tgaattgttg gtattccaac aatatttgca
     7201 tacatagaat tgtctaccat atcttctgta acacctgcca taacacccat agatgtattg
     7261 agaattaaaa aacctactat ggctgccaat gctgcaacac cttctccttc agttaaacca
     7321 acagctaccc caactgcaaa tataagtggt aagttattaa atataatttg acctgaactt
     7381 tccattatac ttattataag ttgaaatgta ggattcgcca aagctggaaa atgagccaac
     7441 aatgcgtctc ctgctaaagc attactcacg ccaagtaata tacctgctgc aggaagtaat
     7501 gcaactggta gcattagaga ttttcctact ttttgtaaaa caccaaatac ttttttcatt
     7561 tacttttctc tccttattat tttatatttt tttaaataaa aaagacttaa gtttataaaa
     7621 agttacatta gtatacttag ttctaaaatt aaacttatgt taatataaat aaacctatat
     7681 taacctaatt tcagaattaa aaataaacta ttataatttt tttataaaca taagtcttgc
     7741 ctgcattatc agtaacaatc ttaatgtttt aaaattatta ttttatatta aattttaaat
     7801 aata
//
LOCUS       DAMKNB010000129         7710 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.135, whole genome shotgun sequence.
ACCESSION   DAMKNB010000129 DAMKNB010000000
VERSION     DAMKNB010000129.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7710)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7710)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7710
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.135"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            127..1185
                     /locus_tag="PC494_003399"
     CDS             127..1185
                     /locus_tag="PC494_003399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium channel family protein"
                     /protein_id="HDF3913853.1"
                     /translation="MNCKWISKIDERKKCHREADSSGYCIFHKENKSDEEIQLMMDTL
                     HKEEISEFNGFVFENEFNAEEILTYNYKILDFSESIFKQKANFKKYIFKKNIIFNYTE
                     FRDKVLFNGCVFLENCDFNRTIFSKHYINDRIFEKVKFKGPDLVVNKVENFPRMDGII
                     FSMCTKFVLKNVEYGKSEYEHGKINYRIARNQATKIGEYEMIGFYYYKERIYSSKIMK
                     RSNYPTFSDYLVEKFFDQIARYTTGYGEKPWNILLVIIAIISVFALLYLFVGIESSNS
                     TLVALDINNIGDYSLSEIFKMYMDLWYFSMATFSTVGYGDMVATSLIGKALAGIEVFF
                     GVTIGAIWASVIIKRMIR"
     gene            1289..2473
                     /locus_tag="PC494_003400"
     CDS             1289..2473
                     /locus_tag="PC494_003400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HDF3913854.1"
                     /translation="MKNALKKIISLAMILVFIIPNYSYADDKSVDKYSKTSILIDQET
                     GRVLYSKEPDMKVPLASLSKMMTFLLAIEAIENKEVKETDKVKIDKSIASVKGSSYKL
                     KDGEEVPLIELMRGLMIVSGNDAAIAIAKHVCKTKEAFVDRMNKKAKEIGMSNTHFLN
                     PNGLPIYDLSNPKKPAKENISTAKDIAILGKYMFDHYEKQVTAITDMETYTNSDRSFE
                     KSNTNALLRIIPEVDGIKTGYTGNAGYCLSFSMVVNKNDKNEKKRRVIGVVLGTNHKN
                     KRTSASLALLKYGKENFNMKKVIDKDSFIGKKYIKGTKELEVTLKAKDELYTILKDDE
                     SIKSEVKIKNIEYPVKKGDTMGIIKYYTNSGDLLGSVDIVSNNSIDNVSLKTKLKMKF
                     AN"
     gene            2680..3393
                     /gene="rpsB"
                     /locus_tag="PC494_003401"
     CDS             2680..3393
                     /gene="rpsB"
                     /locus_tag="PC494_003401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HDF3913855.1"
                     /translation="MSVISMKQLLEAGVHFGHQTRRWNPKMAKYIFTERNGIYIIDLQ
                     KTVKKVEEAYKFTKEVAETGKPILFVGTKKQAQDAIKDEAERCGMYFVNERWLGGMLT
                     NHKTIKTRINKLRELEKMEEEGVFNVLPKKEVIKLRAEKEKLEKYLGGIKDMPELPGA
                     MFVVDPRKENIAIQEAHRLGIPVVGIVDTNCDPEQLDFAIPGNDDAIRAVKLITGAMA
                     TAVIEGRQGAEEEVAEDQE"
     gene            3472..4383
                     /locus_tag="PC494_003402"
     CDS             3472..4383
                     /locus_tag="PC494_003402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HDF3913856.1"
                     /translation="MANITAQMVKELRESTGAGMMDCKKALQEAEGNMEKAVDLLREK
                     GLSKAAKKAGRVAAEGLVAIEMNDDNTVASMVEVNSETDFVAKNEDFKVFVKDAACMA
                     LATDKEDIASLLGETHKEGITLQEVLNNRVAKIGEKLDFRRFAKVVTNGQVAGYIHGG
                     GKIGVLVEMETEARDAKVLELGKDVAMQVAAMNPKYVSRDEVDAEYIAHETEVLTQQA
                     LNEGKPANIVEKMVKGRLEKELKEVCLLEQTFVKNPDITVKQLVADVAKAVGSDIKVV
                     KVVRFEVGEGIQKREENFAEEVAKQLK"
     gene            4468..5172
                     /locus_tag="PC494_003403"
     CDS             4468..5172
                     /locus_tag="PC494_003403"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HDF3913857.1"
                     /translation="MDKPMYKRVLLKLSGEALAGERGFGINNDVVNDIAIAIKKIQEI
                     GVEVAVVVGGGNFWRGRTSEGMDRTTADYIGMLATVMNAMALQDALENIDVATRVQTA
                     IDMRQIAEPYIRRRAVRHLEKERVVIFGAGTGNPYFTTDTTAALRAAEMEAEVILLAK
                     NVDAVYDKDPKVHADAKKFTELSYMEVIQKELKVMDSTATSLCMDNKIPIKVFELTTE
                     NIIRAVKGENIGTTVK"
     gene            5198..5755
                     /gene="frr"
                     /locus_tag="PC494_003404"
     CDS             5198..5755
                     /gene="frr"
                     /locus_tag="PC494_003404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HDF3913858.1"
                     /translation="MKLEIHKQLEEKMNGTIDALKFEFGTIRAGRANAQMLDKIRVDY
                     YGTPTPINQIGAISVPEPRILMISPWDKSAMHEIEKAIANSDLGLNPSNDGEVIRLSV
                     PALTEERRKELAKKASKAAEEFKVRIRNERRDANEKIKKMEKGGELTEDELKKAQDEV
                     QKMTDKFIKEIDTLLSKKEKDIMEV"
     gene            5758..5961
                     /locus_tag="PC494_003405"
     CDS             5758..5961
                     /locus_tag="PC494_003405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3913859.1"
                     /translation="MKKYYNLLGLHVDEVKQYFDEQNINYTVKSIEGKKDKEKLVVPR
                     VIKISEIGDSVELIITYFSDSLV"
     gene            5990..6724
                     /locus_tag="PC494_003406"
     CDS             5990..6724
                     /locus_tag="PC494_003406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HDF3913860.1"
                     /translation="MNNNIIYDIDLNNIPTHIAIIMDGNGRWAKARFLPRTAGHKAGV
                     ETIRDIVKECSKLGVKHLTLYAFSTENWKRPKLEVDTLMNLLSTYLRNEIAELHQNNV
                     KVTAIGDISALPKTCIRELNSAKELTKNNTGVNLNLALNYGSRADIKNALIDIVKNCE
                     SGKIDINNIDEDIIKNYLSTKSIPDPDLVIRTSGEQRLSNFLLWEVAYSEFYFTDIHW
                     PDFKKEELQKAIYVYQRRDRRFGGLK"
     gene            6737..7516
                     /locus_tag="PC494_003407"
     CDS             6737..7516
                     /locus_tag="PC494_003407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HDF3913861.1"
                     /translation="MLTRIIASLALVPLFLFVVYGGIPLYIAETAIVYIALHEFYKAF
                     KIKDVHPIFIIGYLFSIYLAVKNIFNLPLEYTYAVIFILFLASIIYMLMGKNNVIDVS
                     ITFLGVFYIGVFLDFIIITINGFEKGSIYVWLIFVISFMTDIFAYFSGYLLGKHKLIP
                     KVSPKKTIEGAIGGIIGSTLCCILFGYLFGIDLLQLAIIGSIGSVIAQLGDLFASSIK
                     RYVGIKDYGKIIPGHGGILDRFDSVILVAPFVYSAIKFFIR"
BASE COUNT         3182 a          790 c         1462 g         2276 t
ORIGIN      
        1 gtagattaaa aatttaaaac taagaatcta atatatattt tgtaactatt taagtatata
       61 aaataaaata atatccaaac taatacaaaa tagtaataat tgttttgtac tggaggatat
      121 atatttatga attgtaaatg gatatctaaa atagatgaga gaaaaaaatg tcatagagaa
      181 gcagattctt ctggatattg tatctttcat aaagaaaata agtctgatga agagatacag
      241 ttgatgatgg atactcttca taaagaagag ataagtgaat ttaatggatt tgtttttgaa
      301 aatgaattta atgcggaaga aatattaact tacaattata aaatactgga tttttctgaa
      361 tccatattta aacaaaaagc aaattttaaa aaatatattt ttaaaaagaa tattattttt
      421 aactatacag aatttagaga taaagtttta tttaatggtt gtgtattctt agaaaactgt
      481 gattttaata gaaccatatt tagtaaacac tatataaatg accgtatatt tgaaaaagtg
      541 aaatttaaag gacctgattt ggtagttaat aaagtagaaa attttccacg aatggatgga
      601 ataattttta gcatgtgtac aaaatttgtg ttaaagaatg ttgaatatgg aaaaagtgag
      661 tatgagcatg gcaagataaa ttatagaata gctagaaatc aagcaacaaa aattggagaa
      721 tatgagatga taggatttta ctattataag gaaagaattt atagtagtaa aataatgaaa
      781 cgttctaatt atcctacctt cagtgattat ttagttgaaa aattttttga ccaaatagca
      841 cgttacacaa caggttatgg agaaaagcca tggaatatat tattagttat tatagcaata
      901 ataagtgttt ttgctttatt atacttattt gtaggcatag aaagttcaaa tagcacactt
      961 gtagctttag atataaataa tataggtgat tactcactaa gtgagatttt caaaatgtat
     1021 atggatttat ggtattttag catggctaca tttagtacag taggatatgg agatatggtt
     1081 gctacaagtt tgattgggaa agcattggca ggtatagaag tattttttgg agttacaata
     1141 ggagcaattt gggcatctgt gattattaaa agaatgataa ggtaatattt gtgtaaatat
     1201 ggataggtat taattactag atataaattg gactaaatag ggaaaattta aatataaata
     1261 tacttaataa tccaagaagg tgaaaaattt gaaaaatgca ctaaaaaaaa ttatatcatt
     1321 agccatgatt ctagttttta taataccaaa ttattcatat gcagatgata aatctgtaga
     1381 caagtattca aaaacatcta tacttataga ccaagaaaca ggtagagttt tatatagtaa
     1441 agaacctgat atgaaggtac cattagctag tttaagtaag atgatgactt ttttacttgc
     1501 aatagaagct attgaaaata aagaagtaaa agaaactgat aaggtaaaaa tagacaaatc
     1561 tattgcatca gtaaaagggt caagttataa acttaaagat ggtgaagaag tgccacttat
     1621 agagcttatg agaggtctta tgattgtatc aggaaatgat gcggcaattg ctatagcaaa
     1681 acatgtttgt aaaacgaaag aagcatttgt agatagaatg aataaaaaag caaaagaaat
     1741 aggaatgagt aatacacatt ttctaaatcc aaatggtctt ccaatatacg atttaagcaa
     1801 ccccaaaaaa ccagcaaaag aaaatatctc tactgcaaaa gatatagcta ttcttggaaa
     1861 atacatgttt gaccattatg aaaaacaagt aacagctata actgatatgg agacatatac
     1921 aaattcagat agaagttttg aaaaaagcaa tacaaatgca ttattaagaa ttataccaga
     1981 agtagatggt ataaaaactg gatatactgg caatgctgga tattgcttat cattttctat
     2041 ggttgtaaat aaaaatgata aaaatgagaa aaaacgtaga gtaatagggg ttgtattagg
     2101 tactaaccat aaaaataaaa gaacctctgc ttcattagct ctactgaaat atggaaaaga
     2161 aaatttcaat atgaaaaaag taattgataa agatagcttt attggtaaga aatatataaa
     2221 aggaacgaaa gagttagagg ttacattaaa agcaaaagat gaactttata caatattaaa
     2281 agatgatgaa agtataaagt cagaagttaa gattaaaaat atagagtacc ctgttaaaaa
     2341 aggtgatact atgggtatta taaaatatta tactaattca ggtgacttac ttggaagtgt
     2401 agatatagta agtaataata gtatagataa cgtatcatta aaaacaaaat taaaaatgaa
     2461 atttgcaaat taaattcaaa aaatggtata aaatacacaa aaaaatataa aaatagaaaa
     2521 tatggaaaaa atattgttat ttcttcacct ctgtgatata ctactagagg tgaaaaaata
     2581 aaataaatca cacacagcat tgggatcctt aaaaggtgcc tattacatgg ttttttaggg
     2641 agaagatcaa gctggaggta taaaaccagg aggtaagata tgtcagtaat atcaatgaaa
     2701 caattattag aagcaggtgt tcactttggt caccaaacaa gaagatggaa ccctaaaatg
     2761 gctaagtata tattcacaga gagaaatgga atatatataa tcgacttaca aaaaacagtt
     2821 aaaaaagttg aagaagctta caagttcact aaagaagtag ctgaaacagg aaagccaatc
     2881 ttattcgtag gaactaaaaa acaagctcaa gatgcgataa aagatgaagc tgaaagatgt
     2941 ggaatgtact ttgttaatga aagatggtta ggtggaatgt taacaaacca caaaactata
     3001 aaaacaagaa taaataaatt aagagaatta gaaaaaatgg aagaagaagg cgtatttaat
     3061 gttcttccta aaaaagaagt tataaaatta agagctgaaa aagaaaaact agaaaaatac
     3121 ttaggtggaa taaaagacat gcctgaatta ccaggtgcaa tgttcgtagt tgacccaaga
     3181 aaagaaaaca tagctattca agaagctcat agattaggta taccagtagt tggtatagtt
     3241 gatactaact gtgacccaga acaattagac tttgctatac caggaaatga tgacgctata
     3301 agagccgtaa aattaataac tggtgctatg gcaacagctg taattgaagg tagacaaggt
     3361 gctgaggaag aagtagctga agaccaagaa taataatttg acaattaaat ggtaagggtc
     3421 gcccttacca tttataatat ggaatagaat aagtaggagg aaacttaaaa aatggctaat
     3481 ataactgctc aaatggtaaa agagttaaga gaaagtacag gcgcaggaat gatggactgc
     3541 aagaaagctt tacaagaagc tgaaggaaac atggaaaaag cagtagattt attaagagaa
     3601 aaaggattat caaaagctgc taaaaaagct ggtagagttg ctgctgaagg tctagttgca
     3661 atagaaatga atgatgataa tacagttgct tctatggtag aagttaactc agagacagat
     3721 ttcgttgcta aaaacgaaga cttcaaagtg ttcgttaaag atgctgcttg tatggcatta
     3781 gctactgata aagaagatat agcttcttta ttaggtgaaa ctcataaaga aggaataact
     3841 ttacaagaag ttttaaataa tagagttgca aaaataggtg agaaattaga ctttagaaga
     3901 tttgctaaag ttgtaactaa tggacaagtt gctggataca ttcacggtgg tggaaaaata
     3961 ggtgttcttg ttgaaatgga aacagaagct agagatgcta aagttttaga attaggtaaa
     4021 gatgtagcta tgcaagttgc tgctatgaat cctaagtatg tttcaagaga tgaagtagat
     4081 gctgaataca tagcacatga aacagaagta ttaactcaac aagctttaaa tgaaggaaaa
     4141 ccagctaata tagttgaaaa aatggttaaa ggaagattag aaaaagaatt aaaagaggtt
     4201 tgtttattag agcaaacttt cgttaaaaat ccagatataa ctgttaaaca attagttgct
     4261 gatgttgcta aggcagtagg ttctgatata aaagttgtta aagttgtgag attcgaagtt
     4321 ggtgaaggta tacaaaagag agaagaaaac tttgcagaag aagttgctaa gcaacttaag
     4381 taataaccaa agagagaaca cgcaggtgtt ctctttttta aaaaatagaa aaaattggat
     4441 atgaaggatt gaaataggag gtttctgatg gataaaccaa tgtacaaaag ggtattgtta
     4501 aaattaagtg gagaagcatt agcaggagaa agaggttttg gtataaataa tgatgtagtt
     4561 aatgatattg ctattgctat aaaaaaaata caagaaatag gtgttgaagt agctgtagta
     4621 gtaggtggag gaaacttctg gagaggcaga accagtgaag gaatggacag aactactgct
     4681 gactatatag gaatgttagc tacagttatg aatgcaatgg cgctacagga tgcactagaa
     4741 aatatagatg ttgctacaag agttcaaact gctatagaca tgagacaaat tgcagaacca
     4801 tatataagaa gaagagcagt tagacactta gaaaaggaaa gagttgttat atttggtgca
     4861 ggaacaggaa acccttactt tacaacagat acaactgctg ctttacgtgc tgctgagatg
     4921 gaagcagaag ttatattgtt agctaaaaat gttgatgcag tatatgacaa ggatccaaaa
     4981 gtacatgcag atgctaagaa atttacagaa ttaagttaca tggaagttat acagaaagaa
     5041 ttaaaagtaa tggattctac agctacatct ttatgtatgg ataataaaat tccaataaag
     5101 gtatttgagc ttacaacaga gaatataata agagcagtaa aaggcgaaaa tataggaact
     5161 actgtaaaat aatgaagaat gaaggaggag taaaattatg aaactggaaa tacataagca
     5221 attagaagag aaaatgaatg ggacaattga tgctttaaag tttgaatttg gaactataag
     5281 agcaggaaga gctaatgcac aaatgctaga caaaataaga gttgattatt atggaactcc
     5341 aactccaata aatcaaatag gtgctatatc tgtaccagaa ccaagaatat taatgatatc
     5401 tccttgggat aaatctgcta tgcatgaaat agaaaaagcg atagctaact cagacttagg
     5461 attaaatcca tcaaatgatg gtgaggttat aagactttct gtacctgctt taacagaaga
     5521 aagaagaaaa gaattagcta aaaaagctag taaagctgca gaagaattta aagttagaat
     5581 aagaaatgaa agaagagacg ccaatgagaa aattaaaaag atggaaaaag gcggagaatt
     5641 aactgaagat gaattaaaaa aagcacaaga tgaagttcaa aaaatgactg ataaatttat
     5701 aaaagaaata gatacattat tatctaaaaa agaaaaggac ataatggagg tataatattg
     5761 aaaaaatatt ataacctttt aggtcttcat gtagatgagg taaaacaata ttttgatgag
     5821 caaaatataa attataccgt aaaatctatt gaaggtaaaa aggataaaga aaaacttgta
     5881 gttcctagag ttataaaaat atctgagata ggtgatagtg tagaactgat aatcacatac
     5941 ttttctgact ccttagttta aggagtcaga acaatattgg aggcaaaata tgaataacaa
     6001 cattatatat gatatagact taaataacat acctactcat attgctatta taatggatgg
     6061 aaatggaaga tgggcaaaag ctagatttct tccaagaact gcaggacata aggctggagt
     6121 agaaactata agagatatag taaaagaatg ctcaaaatta ggtgttaagc acttaacatt
     6181 atatgcattt tcaacagaaa actggaaaag accgaaactt gaagttgaca cacttatgaa
     6241 cttattatct acatacttaa gaaatgaaat agctgaactt caccaaaaca atgtaaaagt
     6301 aactgctata ggagatataa gtgctttacc aaaaacttgt ataagagaat taaactcagc
     6361 taaggaactg acaaaaaaca atacaggagt taacttaaat ttagcattaa actacggaag
     6421 tagagcagat ataaaaaatg ctcttataga tatagtaaaa aattgtgaaa gtggtaaaat
     6481 agatataaac aatattgatg aagatattat aaaaaactat ttaagcacaa agtctatacc
     6541 agatccagac ttggtaataa gaacaagtgg tgaacaaaga ttgagtaact ttttactttg
     6601 ggaagttgct tattctgagt tttactttac tgatatacat tggcctgatt ttaaaaaaga
     6661 agaactacag aaggctatat acgtatatca aagaagggat agaagatttg gaggacttaa
     6721 gtaaggagat tattttatgc ttacaagaat tattgcttca ctagctctgg ttccattatt
     6781 tctatttgtt gtatatggag gtattcctct atatatagct gagacagcaa tagtttatat
     6841 tgcattgcat gagttttata aggcatttaa aataaaagat gtacatccaa tattcattat
     6901 aggatattta ttttctattt atttagctgt aaaaaatatt tttaatttac cattagaata
     6961 tacttatgca gtaattttta ttttattttt agcaagtata atttatatgt tgatgggcaa
     7021 aaacaatgtt atagatgttt cgattacgtt tttaggagtt ttttatatag gagtattttt
     7081 agattttata attataacta taaatggatt tgaaaaaggt agtatatatg tatggcttat
     7141 atttgtgata tcttttatga cagatatatt tgcatatttt agtggttatt tacttggaaa
     7201 acataagcta attcctaaag ttagtcctaa aaagactata gaaggagcta ttggaggaat
     7261 aataggaagt acactttgtt gtattttatt tggatattta tttggcattg atttgcttca
     7321 attagcgata ataggaagta taggaagtgt aatagctcaa ttaggagatt tatttgcatc
     7381 ttctataaag agatatgtag ggataaagga ttatggaaag ataatacctg gtcatggggg
     7441 tatattagat agatttgata gtgttatatt agttgcacct tttgtatata gtgcgattaa
     7501 attttttatt agataaagat tggttggatt taaaagagca atctataatt gctagtaatg
     7561 aaaatagcta tgtaactttt aaatgcagag atattctgca gttattagtt acatggctat
     7621 tttcattgtt caaaaattta gaagaccttg gggaattgta taagaatagg tattacttta
     7681 taatagtata ctatatttgt agtgagtata
//
LOCUS       DAMKNB010000130         7674 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.136, whole genome shotgun sequence.
ACCESSION   DAMKNB010000130 DAMKNB010000000
VERSION     DAMKNB010000130.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7674)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7674)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7674
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.136"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            95..2323
                     /locus_tag="PC494_003408"
     CDS             95..2323
                     /locus_tag="PC494_003408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip domain-containing protein"
                     /protein_id="HDF3913862.1"
                     /translation="MRHLKKTNSLKEILNWNNIKNLRPSKGLKNILEIFKSDLKDIRG
                     NYAVLVIVLGLAFLPSLYAWFNIKASWDPYGSTANMLVAVTNEDKGNEIAGQKINVGD
                     QLIEQLKDNKSLGWQFVDEKTALEGVKKGTYYASLKIPKNFTKDLTSLITDDVKKGEI
                     IYTVNEKINAVAPKITDKGASTIQLQVNQTIVKTVSEIVLGISNGVGAGIEHSLPKLT
                     KVENSLIDLQKRFDHINKTVDLASDATSKLSDTVKDIKSDLPTIKKTLNDTKLLSSDL
                     KKFLEDTNDNLDELSPLIKSDLNLMVDLSSSASSLTLNLIDAVNSGSEDVPKLIDNLS
                     EKLSNLQSLNDTLVDFLTKLNQLTSNNRLDDVIDNLEDSSNKIDSSISTLNDIKNKVI
                     SGQQPSISALNNVLSLSNGIGRINLNILNNFDSKISKPINSIFANSIKVANDIITVLD
                     KAEAKLPKVEEILTTSLKLSGNAQESISLIRERLPLAKGMLDDLIDTLSKISNGEDMK
                     KLVSLLESDILTKSNFLKEPVEVKTEKLYPIENYGSAMTPFYSVLSTWVGILLISALL
                     STSVHGNYKPYEIYFGRGLTFLSIALVQGFIIGTGDILLLGVTAKHPILLIVLLMFTS
                     MVFNFIVYSLVSVFGNVGKAIAIVLLVVQIGSSGGTFPIQVTPTFFQRINPIMPFTYA
                     IGATREAVGGIYAPNLTKDILVLLLFMILSICLNVLLKGPINRVIKPFNDKFGDSNLT
                     GH"
     gene            complement(2561..2860)
                     /locus_tag="PC494_003409"
     CDS             complement(2561..2860)
                     /locus_tag="PC494_003409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HDF3913863.1"
                     /translation="MYKNINKKQLKEMMKNEKDVLLLDVRTKDEFKEYKIENAINISL
                     QELINNIDEIYDYKDKKVVVYCRSGHRSVTACNLLAEEGFEHLYNLNSGIIDYMS"
     gene            3067..6108
                     /locus_tag="PC494_003410"
     CDS             3067..6108
                     /locus_tag="PC494_003410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp20"
                     /protein_id="HDF3913864.1"
                     /translation="MFKQRLSKLLSSTLVLSMLFTAAPNITFADNTKDNSEKYQSSDI
                     ELHDYSKNAESYTKTKALAKEKIQTLLSKYGAVSAQYALIDNGKIEISGNGGVYSKQD
                     NKNLNKDNMYSIASISKMFTTTAVMKLVDDGKLNLDTPVVKYIPEFKMADDRYKEITP
                     RMLLNHSSGLMGSSFKNTILLADNDSYGHDNFLKELQKQRLKAKPGAFSVYCNDGFTL
                     AEILVERVSGMSFTNFLDKYINNPLNLQNTKTPENSFDSSKLAKAYVPYWEDAVPQDN
                     LNAIGAGGLYSSAENLCTFAQTFMKNSNGILSPASVKAMENKEYLNGLWPEGEDSILG
                     YGLGWDCVNTYPFNQYNLKALTKGGDSLLFHSNLIVLPDENMAVAVLSSGGSSQLNEI
                     IGQEILLSALKEKGKIKEIKPDKTFSKPQQVKMPSSLKENSGLYASSNMIKVDVNDNG
                     TLTVSSPYIENGPEDKYVYIGQDRFVSEKGNSCLKFVKEKNNITYLNMSSYDDVPGLG
                     QTASLYYVAQKVDDNNISNSVKEVWKKRSGKGYYLVDEKYTSQSYMFGSVKASFSLSD
                     ETPGYIVNTKIMDENNSNAFIEIPGVIGRDLSDIKLHKENGTEYLSFGTLTYVSEDSI
                     TNLPAEKSFTCELESNGYAKWYKIGDDIANKKIEVNLPQNSAFAVYDDKGVPVNYSLV
                     TKNNRVRLPKGGVIVFLGSPNARFEVTYQDEVNASALTGTDRYETSIKISQAGWENAE
                     NAVLINDSAIADALAATPFAYKKNAPILLTGSSQINEKTLAELKRLKVKNVYVVGGET
                     SINEKSLDTIKSNNISVSRISGSDRYQTSMNIAKELNNISNISKISVVNGEKGLADAV
                     SIGAVSAQNDMPIILTNENSNITEINNLFKNKKIDKSYVIGGEYTVSKNIESKLQNPQ
                     RISGSTRNETNAKVIKEFYKDSKIDNLYVAKNGMNKQDDLIDGLSVGVLAGKTKSPVM
                     LVGNSLDYNQKELFKTMRFKSVTQIGGNGNENSFKQIKEIA"
     gene            complement(6269..7543)
                     /locus_tag="PC494_003411"
     CDS             complement(6269..7543)
                     /locus_tag="PC494_003411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HDF3913865.1"
                     /translation="MITISHITAKNMYKSLEERINKFPQGAPPSDTLYKILNVLYTEQ
                     EAKLVAQLPIKPFRVKTAAKIWSVSESEAYRVLDKLASKALILDIEDNKGKKYIMPPP
                     MAGFFEFAMMRTRHDIDQKLLAELYYQYMNVEEDFIKDLFYSTETKLGRVYVQEEVLT
                     NDNEVSILDYERATHIIDESTHIGISMCYCRHRMQHVGKACDAPMDICMTFDNVANSL
                     INNKFARRVDKIECKELLHQAYEHNLVQCGENVRKGVTFICNCCGCCCEAMVAAKRFG
                     NLHPVQTTSFIPNINHENCVKCGKCITACPIDAISKVKEDGKEYIKIDEDRCLGCGVC
                     VRNCHKNSIMLLKRDEKIITPANSVHRAVLMAIEKGQLQNLIFDNNALASHRAMGAIL
                     SAILKLEPAKKILASKQLKSVYLDKLLSMNDK"
BASE COUNT         2832 a         1072 c         1100 g         2670 t
ORIGIN      
        1 gacaaaattt taactttact atttgtgtaa aaagtaatat aatttaaaat tgattataaa
       61 tctaactttt ttctttatca aaatatttta ggaggtgaga catttgaaaa aaactaatag
      121 tttaaaagaa attttaaact ggaataatat caagaattta agaccttcaa agggtttaaa
      181 aaatatatta gaaattttta aaagtgacct aaaagatata cgtggcaatt atgccgtact
      241 tgtaatagtt ttaggtcttg cttttttacc atctctgtat gcttggttca atataaaggc
      301 atcttgggac ccttatggaa gcactgccaa tatgcttgta gcagtaacaa atgaagataa
      361 aggaaatgaa atagcagggc aaaagattaa tgtaggagac caattaattg aacaactcaa
      421 agataacaag agtttaggtt ggcaatttgt agatgaaaaa actgctcttg aaggtgttaa
      481 aaaaggtact tattatgcat cacttaagat tccaaaaaat tttacaaaag atttgacatc
      541 tttaattaca gatgatgtta aaaaaggcga aattatctat actgttaatg aaaaaataaa
      601 tgcagttgca ccaaagatta cagataaagg tgcttctaca atacaactac aggttaatca
      661 gactatagta aaaacagtta gtgaaatcgt tcttggtata tcaaacggag ttggtgcagg
      721 aattgaacac agtcttccaa aattgacaaa agttgaaaat tcccttattg accttcaaaa
      781 gagatttgac catataaata agactgttga tttagcttct gatgctactt caaaattatc
      841 tgatacagtt aaagatatta aatctgattt acctacaatt aaaaaaactc tgaatgatac
      901 aaaactatta tcaagtgact taaaaaaatt cttagaggat acaaatgata atttagacga
      961 actttctcct cttattaagt ctgacttaaa tttaatggtt gacctttcat cttctgcttc
     1021 ttctcttaca ttaaatttaa ttgatgcagt aaatagtggc agtgaagatg tacctaagtt
     1081 gatagataat ttatcagaaa aactttctaa tttgcaatct ttaaatgata ctttggtgga
     1141 ttttttaact aaattaaacc aacttacatc aaataataga ttggatgatg tcatagataa
     1201 tcttgaagac tctagcaata aaatagattc atctatatca acattaaatg atattaaaaa
     1261 caaagttata tctggacaac aaccatctat aagtgctttg aataatgttt taagtctatc
     1321 aaatggtatt ggaagaatta atttaaatat tttaaataat tttgactcaa aaatatcaaa
     1381 acctataaat agtatatttg caaacagtat aaaagtagca aatgatataa ttactgtttt
     1441 agataaggca gaagcaaaac ttccaaaggt tgaagaaata cttactactt ctctaaaact
     1501 ttcaggaaat gcacaggaaa gtatatcatt gataagagaa agacttcctt tagcaaaagg
     1561 aatgttggat gatttgattg atactttaag caaaattagt aatggtgaag atatgaaaaa
     1621 attagtcagc ttgcttgaaa gtgatatatt gacaaagtct aatttcttaa aagaacctgt
     1681 tgaggtgaaa acagagaaat tatatccaat tgaaaattat ggttctgcaa tgacaccatt
     1741 ttatagtgtt ctttctacat gggttggtat attacttatt tcagcactat tgtctacatc
     1801 tgtacatgga aactataaac cttatgaaat ttactttgga agaggcctta cttttttaag
     1861 tatagctctt gtccaaggtt ttataatagg aactggagat atattattgt taggagtaac
     1921 agcaaaacat ccaattttat tgatagttct gcttatgttt actagtatgg tatttaactt
     1981 tatagtgtat tctttagttt ctgtatttgg aaatgtagga aaagcaattg caatagtact
     2041 attagtcgtt cagattggtt cttctggtgg tacattccct atacaagtta cacctacatt
     2101 cttccaaaga ataaacccta taatgccatt tacctatgca ataggtgcta caagggaagc
     2161 agttggtggt atatatgctc caaatctaac taaagatata ctagttctat tactatttat
     2221 gattctgtct atttgtttaa acgtacttct aaaaggacct ataaatagag ttataaaacc
     2281 atttaatgat aaatttggcg atagtaattt aactggtcat taaaaaatta attctgtctt
     2341 taaatatatt tttttaataa tattctaagt taatattaaa aggtagtagc taaaaagcta
     2401 ctaccttttt ccaacttaaa aactaatatt tactacaaaa actgtcatag aaaaaaacga
     2461 aaaaattcgt tctttcctaa atttatctta taaatattta gatatattcc tacttaataa
     2521 gcagagctat acatagtatt taatgtataa tttacattat ttaactcata taatcaatta
     2581 ttcctgagtt taaattatat aaatgctcaa aaccttcttc agctaacaaa ttacatgcag
     2641 taacacttct atgaccactt ctgcaataaa ctactacttt cttatcttta taatcgtaaa
     2701 tttcatctat attattgatt aactcttgta aagatatatt tatagcattt tctattttat
     2761 attccttaaa ttcatcttta gttcttacat ctaataataa aacatccttt tcatttttca
     2821 tcatttcttt aagttgcttc ttatttatat tcttatacat atgtctaaaa ttcctccatt
     2881 ttatttatat attacctata ccctttattc tttatacaac aacaaatatt atttttatat
     2941 ttttctctgt tatataaaaa gctatactta taaaagcttt ttttattgat aataatctgt
     3001 tgattaaaat aattaagaat gttatgctaa ttataaatta ttaaaaaggg aaagaggtaa
     3061 tgtaatatgt ttaagcaaag gctctctaaa ttattatcta gtacattagt attgagtatg
     3121 ttatttactg ctgctccaaa tattactttt gctgataata caaaagataa ttccgaaaaa
     3181 tatcaaagtt ctgatataga attacatgat tatagtaaaa acgcggaatc ttacacaaaa
     3241 actaaagctc ttgctaaaga gaaaatccaa actttgctat caaagtatgg tgctgtaagt
     3301 gctcaatatg ctttgattga taatggcaaa attgagattt ctggtaatgg tggcgtttac
     3361 agcaaacagg ataacaaaaa cttaaataag gataatatgt atagtatcgc atctatcagt
     3421 aaaatgttta ctacaacagc tgttatgaag ttggttgatg atggaaaatt aaatttagat
     3481 actcctgttg taaagtatat acctgaattt aaaatggctg atgatagata caaggaaatc
     3541 actccaagaa tgttattaaa tcattcatca gggttgatgg gaagtagttt taaaaacact
     3601 attttattag cagacaatga ttcttatggt catgataatt tcttaaaaga attacaaaaa
     3661 caaagattaa aagctaaacc aggagctttt tctgtttatt gtaatgatgg atttacttta
     3721 gctgaaattt tagtagaaag agtatctggt atgtcattta ctaattttct tgataaatac
     3781 ataaataatc cacttaactt acaaaataca aaaactccag aaaatagttt tgatagttca
     3841 aaactagcaa aagcatatgt accttattgg gaagatgcag ttccacaaga taaccttaat
     3901 gctataggtg caggtggttt atattcaagt gcagaaaatc tatgtacatt tgcacaaaca
     3961 tttatgaaaa attcaaatgg tattctttct cctgcttcag taaaagctat ggaaaacaaa
     4021 gaatatttaa atggtctatg gcctgaagga gaagactcta tacttggata tggtttaggg
     4081 tgggattgtg tcaacactta tccatttaat cagtataatt taaaagctct tacaaaaggt
     4141 ggagattctt tattattcca cagtaatctt atagttcttc cagatgaaaa tatggcagtt
     4201 gcagttcttt cttctggtgg aagtagtcaa cttaatgaaa taattggaca agaaatctta
     4261 ctatctgcat taaaagaaaa aggtaaaatt aaagaaataa aacctgataa aacatttagt
     4321 aagccacaac aagttaaaat gcctagctct ttaaaagaaa atagtggtct ttatgcttct
     4381 tcaaatatga taaaagtaga tgttaatgat aatggtactt taacagtatc ttctccttat
     4441 atagaaaatg gacctgaaga taaatacgta tacataggtc aagatagatt tgtatctgaa
     4501 aaaggtaata gttgtttaaa atttgtaaaa gaaaaaaata atatcacata tttaaatatg
     4561 agctcttatg atgatgtccc tggattaggt cagacagcaa gtttatacta tgtagctcaa
     4621 aaagtagatg acaacaatat atcaaatagt gtcaaagaag tgtggaaaaa aagaagtggc
     4681 aaaggttact atctagtgga tgaaaaatat acttctcaaa gctatatgtt tggctctgta
     4741 aaagcaagtt ttagtctttc tgatgaaact ccaggttata tagttaacac taaaataatg
     4801 gatgagaata actcaaatgc ttttatagaa atacctggtg taataggtcg tgatttatcc
     4861 gacattaaac ttcataaaga aaatggtaca gagtatttat cttttggaac actaacgtat
     4921 gttagtgaag attctataac taatttgcca gcagaaaaat cttttacttg tgaactagaa
     4981 tccaatggtt atgcaaaatg gtataagatt ggtgacgata tcgcaaataa aaaaatagaa
     5041 gttaatcttc ctcaaaattc agcttttgct gtttatgatg ataaaggtgt tcctgtaaac
     5101 tattctttag ttacaaagaa caatagagtt agattgccaa aaggaggcgt aattgttttc
     5161 ttaggaagtc caaatgctag atttgaggtt acatatcaag atgaagtaaa tgcaagtgca
     5221 cttacaggaa ctgatagata tgaaacttct attaagataa gtcaagcagg ttgggaaaat
     5281 gctgaaaatg cagttttaat aaacgattca gcaattgcag atgctttggc tgcaacacca
     5341 tttgcataca agaaaaacgc tcctatatta ttgactggaa gctctcaaat aaatgaaaaa
     5401 actttggctg aattaaagag attaaaagtt aaaaatgtat atgtagttgg tggagaaact
     5461 tctataaatg aaaaatcttt agatactata aaatcaaaca atatctctgt atctagaatt
     5521 tcaggaagtg atagatatca aacttctatg aacattgcta aagaattgaa caatattagc
     5581 aatatatcaa agatttcagt agttaatggc gaaaaaggat tagccgatgc agtaagcatt
     5641 ggagctgtat cagctcaaaa tgatatgcct ataatactta ctaatgaaaa tagtaatata
     5701 actgaaataa ataacttgtt taaaaacaaa aagattgata aatcttatgt aatcggtgga
     5761 gaatatacag tttctaaaaa tatagaaagt aaacttcaaa atccacagag aatatcaggt
     5821 agcactagaa atgaaactaa tgcaaaagta ataaaagaat tttacaagga ttctaagata
     5881 gacaatttat atgttgctaa aaatggaatg aataaacaag atgatttaat agacggatta
     5941 tctgttggag ttttggctgg aaaaactaaa tctcctgtaa tgctagtagg aaactcacta
     6001 gattataatc aaaaagaact atttaaaact atgagattta aatctgtaac acaaattggt
     6061 ggaaatggaa atgaaaactc atttaagcaa ataaaagaaa tagcttaaca taactaaaaa
     6121 aggctgtatt caagtaatat taattgaata tagccttttt ttatttaagt tataagtttt
     6181 atatgtgtaa aaattaaatt taaatattaa atgataagtt tattaagata tagataagtc
     6241 taaaactttg ccttttttaa gttagtttct atttatcatt catacttaac aatttatcta
     6301 aatatactga ctttaattgt ttactggcta aaatcttttt agctggttca agctttaata
     6361 tagctgacag tatagctccc atagctctat gactagccag agcattatta tcaaaaatta
     6421 aattttgtaa ctgccctttt tcaattgcca taagaactgc tctatgtact gaatttgctg
     6481 gagttattat tttttcatct ctctttaata acataatgct atttttatgg caatttctaa
     6541 cacaaactcc acaacctaga catctatcct catcaatttt tatatattct ttaccatctt
     6601 ccttaacctt gcttatcgca tctattggac atgcagttat acatttacca cactttacac
     6661 aattttcatg gtttatattt ggtataaaac ttgttgtctg tactggatga agatttccaa
     6721 atcttttagc tgctaccatt gcttcacagc aacatccaca gcaattacat ataaacgtaa
     6781 cccctttcct aacattttct ccacattgaa ctaagttatg ttcatatgct tgatgaagta
     6841 gttctttaca ttctatttta tccacacgtc ttgcaaattt attatttatt aaagaatttg
     6901 ctacattgtc aaacgtcata catatatcca taggagcatc acaagctttt ccaacatgtt
     6961 gcattctatg tctacagtaa cacatactta tacctatatg agttgattca tcaattatat
     7021 gagtagccct ttcataatct aaaatactaa cctcattatc attagttaaa acttcctctt
     7081 gaacgtatac tcttccaagc ttcgtttctg ttgaataaaa taaatctttg ataaaatctt
     7141 cttctacatt catatattga tagtaaagct ctgccaaaag tttttggtct atatcgtgtc
     7201 tcgttctcat catggcaaac tcaaaaaaac cagccattgg aggaggcatt atatatttct
     7261 tccctttatt atcttctata tctagtatca gagccttact agcaagttta tccaatactc
     7321 tatatgcttc actttcactt acactccaaa ttttagctgc tgtttttact ctgaaaggct
     7381 ttattggaag ctgagcaact aacttcgctt cttgttctgt atatagtaca tttagtattt
     7441 tgtataatgt atcagatggt ggagcacctt gtggaaactt gtttattctt tcctctaaac
     7501 ttttatacat attcttcgca gttatatgag aaatagtaat caccttcttt ttcttttgtt
     7561 ttccaataaa atcaaatatt ctttcttatt atatattctc ttactttata taataccaat
     7621 tctttctaaa tagttaaata cctctagtaa tttattatta gatttcttat ataa
//
LOCUS       DAMKNB010000131         7396 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.137, whole genome shotgun sequence.
ACCESSION   DAMKNB010000131 DAMKNB010000000
VERSION     DAMKNB010000131.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7396)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7396)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7396
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.137"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            complement(56..1003)
                     /locus_tag="PC494_003412"
     CDS             complement(56..1003)
                     /locus_tag="PC494_003412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HDF3913866.1"
                     /translation="MFYFLKVKVGDIMDEVKEFLVLEEEEEVRLDIYLAEQLGDMSRS
                     YIQKIIKDGKVKVNNKVEKARYLVKEEDNIVIEIPEPKVLEVLPQDIPIDIVYEDDDV
                     LIINKPQDMVVHPAPGNYENTLVNGILYHCKDKLSSINGVIRPGIVHRIDKDTSGLLM
                     IAKNNYAHNFLAEQLKEHTITREYEFICYGVVKEDKITVDKPIGRNPKDRLKMAVVKD
                     GKNAITHFEVVERFDKFTHMRARLETGRTHQIRVHALSINHPLLGDYVYGPKETKFKL
                     KGQTLHAKKLGFIHPTTKEYIEFNSELPEYFKEVIKKIK"
     gene            complement(972..1418)
                     /gene="lspA"
                     /locus_tag="PC494_003413"
     CDS             complement(972..1418)
                     /gene="lspA"
                     /locus_tag="PC494_003413"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HDF3913867.1"
                     /translation="MLYILIIILLIGLDQLSKIWVLNNLVDVSTIPIINNVFHLTYVE
                     NRGAAFGLLQNNQWIFIIVALLATVFGLYYLNTRKVHIFGRLGIILIISGALGNLIDR
                     VRLGFVVDYFDFRIIWEYVFNIADVFVVVGTVFLCIYVLFFESKSR"
     gene            complement(1728..2507)
                     /locus_tag="PC494_003414"
     CDS             complement(1728..2507)
                     /locus_tag="PC494_003414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HDF3913868.1"
                     /translation="MKKIIWGICICLLSIVGVYTYNHNTHNQDSSKEAYSLNDNIKDD
                     YEDVIIKKGNEDEKILALTFDDGPDEDFTPQVLDILKKNDVKATFFVVGEKVEYNKEL
                     LKRQYDEGHEIGNHTFTHINVAKNSYSSVEKEITDTQNIIKSVIGVEPKIFRPPYRAM
                     SKSVCDIIVSKGMNIILWSNLDPRDWSNPGVDAIINTILTKVQNGNIILLHDYNTKRN
                     DKSQTIQALEVVIPKLKERGYKFVTVSELIQHLDKNKQVQK"
     gene            complement(2562..3044)
                     /locus_tag="PC494_003415"
     CDS             complement(2562..3044)
                     /locus_tag="PC494_003415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TraR/DksA C4-type zinc finger protein"
                     /protein_id="HDF3913869.1"
                     /translation="MDTKKYKDKLLKERENLTNLVEDMKDNTLFGDTTKHTSEKYSSG
                     ELSSYDNHIGDMGTDLYMQNMQNSLINHEEGRLYQIDLALSKIENGTYGICDLCHNQI
                     DLERLDILPDTSLCNDCAKKENNLLGDAMQNPDVEDSNFYSEDLTNLTDLNKNGILRD
                     "
     gene            complement(3310..4731)
                     /locus_tag="PC494_003416"
     CDS             complement(3310..4731)
                     /locus_tag="PC494_003416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon starvation protein A"
                     /protein_id="HDF3913870.1"
                     /translation="MVSFLGSIVVLIVGYFVYGTFVEKVFGTNDKNQTPAIACRDGVD
                     YVPMKWKRIFLIQFLNIAGLGPIFGAIQGALFGPSAFLWIVFGTIFAGGVHDFASGYL
                     SMKNKGTSASELVGLYLGNGAKIAMRIFSVILLVLVGVVFVTGPAGLLKTLTGVNAQI
                     WVGVIILYYIMATVLPIDKLIGKIYPLFGAALLIMAVGVAGGLIIKGYNIPNINLQNM
                     NPNGTPLFPYLFITIACGAISGFHATQSPLMARCVEKESEARPVFYGSMVAEGIIALV
                     WAAAAMSYFHGIPQLNVIFNDGGAATVVNTVSVGLMGPIGGALAILGVVACPITSGDT
                     AFRSARLTIADAMNYNQDAVKNRFLIALPLFAVGVALTFIDFNIIWRYFSWANQTLAM
                     IMLWTGSAYLVKANKNHYITTLPALFMTVVTFSYIMQAKEGFRLPVNISNGIGVIVAI
                     ILGLLFFKKAKHIKEQNNHKLAS"
     gene            complement(4877..5647)
                     /locus_tag="PC494_003417"
     CDS             complement(4877..5647)
                     /locus_tag="PC494_003417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001295458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF3913871.1"
                     /translation="MRAIIVEDEFPARKELRYFIENKSGIEVVSEFTNGIEVLDFIQE
                     NKIDVIFLDINIPHLDGMLLAKTLNQFKSRPKIVFITAYESYAVDAFSLDVFDYILKP
                     YSEERIISMLNKLEKSEMSDIELFNVNSNLYKYKKEAVNQEIEEITHKISLWKGDKLV
                     VIDIDDIYYCEANERQTFIYTEKEKFILKEGISEVENLINDKTFFRTHRSYIVNLTKV
                     KEIIPWFNNTYILKLKNSDYEVTVSRSKVKEFRLLMHI"
     gene            complement(5652..6854)
                     /locus_tag="PC494_003418"
     CDS             complement(5652..6854)
                     /locus_tag="PC494_003418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HDF3913872.1"
                     /translation="MKTSILIALIEKTSLIVVLFLLITKLKIFKQIFQKEEYSFNDLV
                     CIALVFTFLAIFGTYSGINYMGSIVNTRIISIVSGGILFGPMVGITAGVFSGIHRYFM
                     DIGGITSVPCLLSSILAGVLSGFLYKRIPKQHRVMYGILVGMISESFTILLIYLISYP
                     HSLAIQIIGGIYLPLIVGQIGIGFVISIVEGIEKDKKDIEARNKAEIKALQRQINPHF
                     LFNSLNTIASFIRFSPDKARELIINLSTYLRYNLEYSDNLIDINKEIEQVKSFVEIEK
                     ARFGELLTVSYDIEDVNIKIPSLIIQPLVENAIIHGILESGRAGVVKISIKKLPYSLE
                     NTVRISIEDNGIGISEEIINNVYQDNMPENKIGLYNVHLRLKLMYGRGLNIRRIDNGT
                     LIVFYVKE"
BASE COUNT         2468 a         1279 c          719 g         2930 t
ORIGIN      
        1 aaatttattt acttatataa aaacaaaaaa tgatttataa gtattataca aatggttatt
       61 ttatcttttt aataacttcc ttaaaatact caggtaattc tgaattaaat tcgatatatt
      121 ccttagtagt aggatgtata aatcccaact tcttagcgtg caaagtttgt ccttttaatt
      181 taaatttagt ttcttttgga ccatatacat aatcacctaa aagtgggtga tttatagaca
      241 aagcatgaac tcttatttga tgagttctac cagtttcaag cctagctctc atatgtgtaa
      301 acttatcaaa tctttctaca acttcaaagt gagtgattgc attttttcca tcttttacta
      361 cagccatttt taatctatcc ttaggatttc tccctatagg tttatcaaca gttattttat
      421 cttctttaac cacaccatag catataaatt catactccct agttatagta tgttccttta
      481 actgttctgc tagaaaatta tgtgcataat tgttcttagc tatcataaga agaccagaag
      541 tatctttgtc tattctatga actataccag gtctaataac tccatttatt gatgacaact
      601 tatctttaca atgatataaa atcccgttta ctaacgtatt ttcatagttt ccaggagcag
      661 gatggacaac catatcctga ggtttattta ttattaagac atcatcatct tcatatacaa
      721 tatctattgg aatatcttga ggtaaaactt ctaatacttt aggttctggt atctctataa
      781 caatattatc ttcctcttta accagatatc tagctttttc tactttatta ttaaccttta
      841 cttttccatc ttttataatt ttttgtatat aacttcttga catatcacct aattgttctg
      901 ctagataaat atcaagtcta acttcttctt cctcttcaag tactaaaaac tcttttactt
      961 catccattat atcacctact tttactttca aaaaataaaa catatataca taaaaacaca
     1021 gttcctacaa ctacaaatac atcagctata ttgaatacat attcccatat aattctaaag
     1081 tcgaagtaat ctactacaaa acctaatcgt actctatcaa ttagatttcc caatgcacca
     1141 gatataatta atataattcc caaccttcca aatatatgta ctttccttgt attaagatag
     1201 tatagtccaa atactgttgc aagtaatgca acaattataa atatccattg attattttgt
     1261 aataatccaa atgctgcacc tctattttcg acataagtta aatgaaatac attatttatt
     1321 attggtattg ttgatacatc caccaaatta ttcaataccc atattttaga cagttggtct
     1381 aaacctatga gtagaattat tattaatata tatagcaatg atttttcccc ctataaatta
     1441 tttaaaaacc aattttattt gaagcacact attattatta tacaaaaaaa atgctctaaa
     1501 gagcaacttt attaaaattg tattttctta ataaagctag aacaaaattt aaaatagtac
     1561 tacttttttt atattgtaga tttctacata tttaaaatca tatcattatg tataaaaaat
     1621 ttaaaaatac catactaatc aatatttttt gtgtatttta tagattaaag attaatgatg
     1681 tctgtaattt aaacttacaa tcaccactaa tcttcaaaca aatattttta cttttgcact
     1741 tgcttatttt tatctaaatg ttgtataagt tcagatactg ttacgaattt atatcctctc
     1801 tcttttaatt taggaattac tacttctaaa gcttgtatag tttgtgattt atcatttctt
     1861 ttagtgttat aatcatgtaa aagtattata ttaccatttt ggacctttgt aaggatagta
     1921 tttataattg catctactcc agggttagac caatctctag ggtctaagtt tgaccaaaga
     1981 attatattca tgcctttaga aactataata tcacagacac ttttactcat ggctctatat
     2041 ggaggtctaa atatctttgg ttctactcct attacacttt ttataatatt ttgcgtatct
     2101 gttatttctt tttcaacact actataacta ttttttgcaa catttatatg tgtaaatgta
     2161 tgattcccta tttcatgccc ctcatcatat tgtcttttta ataattcttt gttatattct
     2221 actttttctc caactacaaa aaaagttgct tttacatcat ttttctttaa tatatcaagt
     2281 acttgtggtg taaaatcctc atctggacca tcatcaaaag tcaatgctaa aattttttca
     2341 tcctcatttc ctttttttat tattacatct tcataatcgt cttttatatt gtcatttaaa
     2401 ctatatgctt cttttgaact atcttgatta tgtgtattat gattatatgt atatacacct
     2461 actatagata ataaacatat acatataccc catattattt tcttcatgtc attacctctt
     2521 ttctaattca ttctagcaat atattttata atgtcagttt tttaatctct caatattcca
     2581 tttttattta aatcagttaa atttgttagg tcttctgaat aaaagttaga atcttctaca
     2641 tcagggtttt gcattgcatc acctaataaa ttattttctt tctttgcaca atcattacat
     2701 aaacttgtat ctggcaatat atccaatctt tctaaatcta tttgattatg acataaatca
     2761 caaatcccat atgttccatt ctctatttta gataatgcta agtctatttg atacaatctt
     2821 ccctcttcat gatttattag actgttttgc atattttgca tatataaatc tgttcccatg
     2881 tctcctatat gattatcata actagataat tctcctgatg aatacttttc acttgtatgt
     2941 ttagttgtat ctccaaataa agtattatct ttcatatcct ctactaaatt agttaaattt
     3001 tctctttctt tcaataattt atctttatat tttttagtat ccatttttaa cacctctaat
     3061 tttaatattt acatcataaa aatagtatgt ggaaaagtaa attaaacata caataaaaat
     3121 aagatttgat tcgaaaaatg gaatgtctca aaatgaaatt tttagttcat ttaaccctct
     3181 tttttatatg aaatcaaata tatttttatc ctttcagcaa taaaaaagag acttatctct
     3241 attttgagat agtctcttct ttgaacataa tttaaataca attttttaat ttttatagtt
     3301 attattttac taacttgcca atttatgatt attttgttct ttaatatgtt ttgctttttt
     3361 aaagaataaa agaccaagaa ttattgctac aataacacct attccattag atatattaac
     3421 tggtagtcta aatccttctt ttgcttgcat tatataacta aatgttacta cagtcataaa
     3481 aagtgctggt aatgtagtta tataatggtt tttatttgct ttgactaaat atgcagaacc
     3541 agtccacaac attatcattg caagtgtttg atttgcccaa gagaaatatc tccaaattat
     3601 attaaaatct ataaatgtaa gagcaacacc aactgcgaat aatggtaaag ctattaaaaa
     3661 tctatttttg actgcatctt gattataatt cattgcatct gctattgtca gcctagcact
     3721 tctaaatgct gtatctccag aagttatagg acatgccaca actccaagta tagctaaagc
     3781 tcctccaata ggccccatta atccaacaga tactgtattt actactgttg ctgctccacc
     3841 atcattaaat atcacattaa gttgaggtat gccatggaaa tatgacatgg ctgctgctgc
     3901 ccaaactaaa gctattatac cttctgcaac cattgaccca taaaatactg gtcttgcctc
     3961 actctctttc tcaacacatc tcgccataag tggtgattga gttgcatgaa aacctgatat
     4021 tgctccacat gctattgtta taaataagta tgggaataaa ggtgttccat ttggattcat
     4081 attttgtaaa tttatatttg gtatgttata cccctttatt attaatcctc cagctacacc
     4141 tactgccata attaataatg ctgctccaaa taaaggatat attttaccaa tcaatttatc
     4201 tattggtaaa acagtagcca taatataata aagtattatc actccaaccc atatttgtgc
     4261 gtttacacct gtcaatgtct ttaataatcc tgctggacct gttacaaata caactccaac
     4321 caatactaaa agaataacac taaatattct cattgctatt tttgcaccat ttcctagata
     4381 aaggcctacc aactctgatg cagatgtacc tttgtttttc attgatagat atcctgaagc
     4441 aaaatcgtgt actccaccag caaagattgt tccaaacaca atccataaaa atgctgatgg
     4501 tccaaataat gctccttgta tagctccaaa tatcggacct aaccctgcta tatttagaaa
     4561 ctgaattaaa aagattctct tccatttcat tggcacataa tctactccat ccctacaagc
     4621 tatagctgga gtttgatttt tgtcattggt tccaaaaacc ttttctacaa aagtaccata
     4681 gacaaaataa cctactataa gtactactat tgaacctaaa aagcttacca taaattcatc
     4741 cccttagttt ttatataatt gctttataaa tttttatgag tttaagaaaa ctatttccag
     4801 ttcaaatagt aatacttttt tatgctaata taaatattaa ttacattaag tgcatattta
     4861 agtacatgaa atgactttat atatgcatta acagcctaaa ttcttttact ttgcttctac
     4921 ttacagttac ttcataatca ctatttttta attttaatat gtatgtatta ttaaaccatg
     4981 gtataatttc ttttactttg gttaagttta cgatataaga cctatgtgtt ctaaaaaatg
     5041 ttttatcatt tataagattt tcgacttctg atatgccttc ttttaatata aacttttctt
     5101 tctcagtata tataaatgtc tgcctttcat tagcttcaca gtaatatata tcatcaatat
     5161 ctattacaac taatttatca cctttccaaa ggctaatttt atgtgttatt tcttctatct
     5221 cctgatttac tgcttccttc ttatatttgt ataaattact atttacatta aatagttcaa
     5281 tatcactcat ctcacttttt tctaatttat tcagcataga aataattctc tcttcagaat
     5341 atggtttcaa tatataatca aatacatcca aagaaaaagc atctactgca taactttcat
     5401 atgctgttat aaaaacaatt ttaggtcttg atttaaactg atttaatgtt tttgcaagta
     5461 gcattccatc aagatgaggt atatttatat ctaaaaaaat tacatctatt ttattttcct
     5521 gaataaagtc taacacctct ataccattgg taaattcact tactacctcg attccacttt
     5581 tattttcaat aaaatatctc aattcctttc ttgctggaaa ttcatcttcc actattatag
     5641 ctctcatact tctactcctt tacataaaat actatcaaag tcccattatc tattcttctt
     5701 atattaagcc ctcttccata catcagttta agccttaaat gtacattata aagcccaatc
     5761 ttattttctg gcatattatc ttgatataca ttatttataa tttcctcact tatacctata
     5821 ccattatcct ctattgatat tctcacagta ttttctaatg aatacggtaa cttttttatg
     5881 gatattttca ctacaccagc tctaccactt tctaaaatac catgtattat tgcattttcc
     5941 actaatggtt gtataatcaa acttggaatc tttatattta catcttctat atcataagat
     6001 acagttagta attctccaaa cctagctttt tctatctcta caaaagattt aacttgttca
     6061 atctctttat ttatatcaat taagttatca ctatattcaa gattatatct tagataagtt
     6121 gataaattta ttattaactc tctagcctta tctggactaa atcttataaa tgaagctatt
     6181 gtgtttaggg aattaaacaa aaaatgtgga ttaatttgtc tttgaagtgc ttttatttct
     6241 gctttatttc tcgcttctat atctttttta tctttctcaa tcccctctac tatagatata
     6301 acaaatccta ttccaatctg cccaactatt aaaggtaaat atattccacc gattatttga
     6361 attgctaaag aatgtggata tgatattaag tatataagta atatagtaaa actttcagaa
     6421 atcatgccta ccaatattcc atacattact ctatgttgtt ttggtatcct cttatataga
     6481 aatcctgata atacacctgc tagtatactt gataaaagac atggaacaga tgttatcccc
     6541 ccaatatcca taaaatatct atgaatccct gaaaaaactc ctgctgtaat acctaccatc
     6601 ggaccaaata aaatgccacc tgatactata gatattattc tagtgtttac tattgacccc
     6661 atataattta taccactata agttccaaat atggctaaaa aagtaaaaac taatgctata
     6721 cagaccaagt cattaaaact atattcttcc ttttgaaata tctgcttaaa tatttttaac
     6781 tttgttatta gaagaaacaa tactacaata aggcttgtct tttctattaa tgcgattaaa
     6841 attgatgttt tcataatccc cctttaaaaa ataaattttt acacactcta aatttattat
     6901 ggttgttata aattacatat ttgaagtaat cctatcacaa aactttccac atttaatctt
     6961 ttaattaaat aagaaatagt tgtacttcta ttaacaacta atactagcta gcataagctt
     7021 gtaataactt gtagttatta ttaactttac aattctagta tttaatttta tactttagaa
     7081 atctcttttc ttagaaataa tactttcgaa tatcatataa tacaatatta tgtagattct
     7141 tactcataca acatatttct ttaaaaattt tatactattc tttgttcaaa tatctcattt
     7201 gatttaattg tgttaaacac acattatcat ctctctgtta tatatttatt atatagccgt
     7261 atatcgataa agtaaataaa tcccatattt aaaataatat gtttgacaat aaattattat
     7321 aatgtatatt taccataata atttgtcaac cttgaaagtt acttctataa ttattgttaa
     7381 ataattcttc taaaaa
//
LOCUS       DAMKNB010000132         7333 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.138, whole genome shotgun sequence.
ACCESSION   DAMKNB010000132 DAMKNB010000000
VERSION     DAMKNB010000132.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7333)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7333)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7333
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.138"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            161..3340
                     /locus_tag="PC494_003419"
     CDS             161..3340
                     /locus_tag="PC494_003419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HDF3913873.1"
                     /translation="MKIDMIYKLIRRNTEPSRWSRGVKYYTHQLVDYIDIDIDDLQNN
                     LLTFRGGVNSEDNYSFYFNSITIDIKHFKIIENDCSCADCQSKGKSIFICKHIVAIVI
                     KSLKQIKNKKDVPPILIDILGADKDKLSNTNSKTSLDLSKQLLSLLDNTKRERVNLDV
                     LINVDSNKAIAEFKIGIDKMYILKNITEFAYSKLNGYELDFGKKFTYNPNIHYFADED
                     EKLVDIIEEYGTNLSYNFSSSHSKKFMEINASSLKQFLNAIKYKDFTLIFSKEEYHPK
                     ILNDTLPVRFDFKNIEDKIVLYSKDSLPVPLTKKNDVLLYDGNIYLLSHKKAHDYSKI
                     YQILSKTKELKFDKEDSKDVLGLLVPRLKSISQEVHLDDNIKNNITKDFKSEFYFDMI
                     DGNICCDVKYIYDDEDKKFVLPNIQKEATIENKLTSSQFTKENNHYVFKGTDHDLFTF
                     LDLQLESLKEFGDIYYSEKFKLKKIYNASSIQASINQTNQNYLEFNFNISDINPKEYK
                     DILKAFQEKRTFYKLKDGNFIDLSERETKDFFELVENLDIMDKSKNNKIHKNKALYIN
                     DVIRSKNLKFIDGKKELDSICEKFRNFDSINLEIPANLNANLRDYQINGLNWFKVLDY
                     YKFGGILADEMGLGKTIQTIAFLLSLSNKKSLIVTPTSLIYNWKNEFEKFAPDIKVLL
                     IHGNKRDREKCFMELENFDVILTTYGTLRNDLEKYSEIKFDYCILDEAQNIKNPVALV
                     TESVKSINAENKFALTGTPMENNLLELWSIFDFIMPGYLYSKAKFQELFINKEDNVKN
                     LKKLIKPFILRRSKKQVMKELPDKIEKNFFVELNKEQKKIYSVYSKDIQDKMKDKNLK
                     KDKIVIFSYLTKLRQLCLDPSIVVKDYNKKSSKIETCLEILRDSINENHKILLFSQFT
                     SVLKNISKELDKYKIKYHYIDGKTNAKERLELVDEFNNSMDKKVFLISLKAGGTGLNL
                     TSADMVIHFDPWWNPSVENQASDRAHRFGQKNSVQVIKLIAKGTIEEKIIKLQESKKE
                     LINQFINGELSNEGVLKSLSDEEIINLFN"
     gene            complement(3625..4389)
                     /locus_tag="PC494_003420"
     CDS             complement(3625..4389)
                     /locus_tag="PC494_003420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDF3913874.1"
                     /translation="MAYFNYNDKQCYYNEIGDGTPLLFLHGNTASSKMFNDIIDFYKD
                     EYKVILIDFVGHGKSQMVDKFSADLWFDEAMQVICFLEAMNYKKVNIIGSSGGALVAL
                     NVALERPDLVNKVIADSFEGEVPLESFVQNVKIEREASKQDDGAKAFYIYNQGENWEK
                     VVDNDTEAIFEHYKTIGKFFHKPLETMQPEVLLTGSREDEFVSLISSDFFENTFSLLL
                     EKIKNGKMYLFDKGGHPAILSNGLDFSNVAKKFLEE"
     gene            complement(4545..4778)
                     /locus_tag="PC494_003421"
     CDS             complement(4545..4778)
                     /locus_tag="PC494_003421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3913875.1"
                     /translation="MKAEDMKRKVSPIDLERILVTGGVIKHEDSIWLLDFWGNKDIAG
                     ILLMPPTRHVILHLNDCCKWKEYFRTKKKFYRS"
     gene            complement(4852..6345)
                     /locus_tag="PC494_003422"
     CDS             complement(4852..6345)
                     /locus_tag="PC494_003422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HDF3913876.1"
                     /translation="MKYTFEKFKLNEKILKSLKSLGYNIPSRVQREVIPKLLKGQNLV
                     VRSKTGSGKTASFAIPLCENINVDYNNVQALIVVPTRELALQVKDEISDIGRLKKVRC
                     SAIFGKQSIKDQIAELKQRVHIVVATPGRILDHINRGSIKLENVKYLVIDEADKMFNK
                     GFVEQMEKILLNLPKEKIVSLFSATIDEEIKYICEKYMLDYSVINIEENESDTNQKTR
                     QIDDKIIKANGREKYILLKELIYSENPKSVIIFCNTKEKVSKLYNKMSKEGFLIRELH
                     ADLSQERRIFVIKDFKNQKFNILVSSDVASRGIHIDDISLVINYDVPQDKENYIHRIG
                     RTGRKGNSGKAITIVTEKDEKYIENIETYIGYKINELKDIEQSRITHGKVLFEEYSKG
                     VLKEVSKRKKVDKNSYKSKDIKLNIESEVVKLYLNAGKKKKIRVLDIVGAFSNIKGIT
                     NDDIGVIEVQDLCSYVDILNYKGDLILKKYKEIPIKKKMVKVKRDIR"
     gene            complement(6673..7215)
                     /locus_tag="PC494_003423"
     CDS             complement(6673..7215)
                     /locus_tag="PC494_003423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HDF3913877.1"
                     /translation="MKICITVGHSILKGGKSTGVNGIVDEYNYNKKLAPMLAEMLISQ
                     GNTVDVIICPERHFMSEREEFFYRVPKVNSGKYDLLVELHLNKADGTQCGTEVLYYGT
                     EGLEYAKRVSNRLGELFENRGAKKRENLYILRNTNPVAIQIESFFCDNVNDCNKANES
                     GYDYIARLITEGILNKDINM"
BASE COUNT         2689 a         1061 c          821 g         2762 t
ORIGIN      
        1 tataagataa ttcaataaaa atctaatagt aaattgttat ttacacatat attgtgatag
       61 ataaaagcta ttcatatctg ccttaatttt agtcttaaat ttagagtgta aattgaatgc
      121 atttagatta taatatatac agtgaggtaa ggtgaataat atgaaaatag atatgatata
      181 taaactaata agaagaaata cagaaccatc aagatggtca agaggtgtaa aatattatac
      241 tcatcaatta gttgattata tagacataga tattgatgac ctacaaaata acctgttgac
      301 atttcgtggt ggagtcaatt ctgaagataa ttatagcttt tattttaatt caataactat
      361 agatataaag cactttaaga taattgaaaa tgattgtagt tgcgctgact gtcaatcaaa
      421 gggcaaaagt atttttatat gtaagcatat agttgctatt gtgataaaaa gcttaaaaca
      481 aataaaaaat aaaaaagatg ttcctcctat tctaatagat atattaggtg cagataagga
      541 taagctttct aatacaaatt ctaaaaccag cttagattta agcaagcaat tactttcttt
      601 gttagacaat actaaaagag aaagggttaa tttagatgta ttgataaatg tggattcaaa
      661 taaagcaatt gctgaattta aaataggaat tgataaaatg tacattttaa aaaatattac
      721 tgaatttgca tattcaaaac ttaatggata tgaattagat tttgggaaga aatttactta
      781 caaccccaac attcattatt ttgctgatga agatgagaag ttagtagata ttatagaaga
      841 atatgggaca aatctttcat acaacttttc ttcatcacat tcaaaaaaat ttatggagat
      901 aaatgcaagc tctttaaaac aatttttaaa tgctattaag tacaaggatt ttacccttat
      961 tttttctaaa gaggaatatc atccaaagat attaaatgat actctacctg taaggtttga
     1021 ttttaaaaat atagaagata aaatagtctt atattctaaa gattcactac ctgttccact
     1081 tactaaaaaa aatgatgtac ttttatatga tggcaatatc tatttattat cacataaaaa
     1141 agctcatgat tattcaaaaa tatatcaaat attatcaaag actaaagagt taaaatttga
     1201 taaagaggat tctaaggatg ttttaggatt gctagttcct agattaaaat ctatatctca
     1261 agaagttcat ttagatgata acataaaaaa taatataaca aaagatttta aatctgagtt
     1321 ctactttgat atgattgatg gcaacatatg ttgtgatgta aagtatatat atgatgatga
     1381 agataaaaaa tttgtgctcc ccaacataca aaaggaagct actattgaaa ataaacttac
     1441 ttcttcacaa tttacaaagg aaaataatca ttatgtgttt aaaggaactg accatgacct
     1501 atttacattt ttagatttac aattagaatc tctaaaggaa tttggagata tatattattc
     1561 tgagaagttt aaattgaaaa aaatatataa cgcttcatca attcaagctt caatcaatca
     1621 gactaaccag aattacctag aatttaattt taatatatct gatataaatc caaaagagta
     1681 caaggatatt ttgaaagctt ttcaagaaaa acgtactttt tataaactta aagatggaaa
     1741 ctttatagat ttatcagaaa gagaaacaaa agattttttt gaattagttg aaaatctaga
     1801 tataatggat aaatcaaaaa ataataaaat tcataaaaat aaagctctat atataaatga
     1861 tgtaatacgt agtaaaaatt taaagtttat agatggtaaa aaagaactag acagtatatg
     1921 tgaaaaattt agaaattttg atagcataaa tttagaaatt cccgcaaatt taaatgcaaa
     1981 ccttcgtgac tatcaaataa atggcctcaa ttggtttaaa gttttagatt attataaatt
     2041 tggtggtata ttagctgatg aaatgggtct tggtaaaaca atacagacta ttgcattttt
     2101 attatcatta tctaataaaa aaagtcttat tgttacaccg acatcactca tttataattg
     2161 gaaaaatgaa tttgaaaagt ttgctccaga tataaaagtt ttattgatac atggaaataa
     2221 aagagataga gaaaaatgtt ttatggaatt agaaaatttt gatgtaatac ttacaacata
     2281 tggtactctt agaaatgatt tagaaaaata tagtgaaata aagtttgatt attgtatatt
     2341 agacgaagct caaaatataa aaaatccagt agctttagta actgagtctg taaaaagtat
     2401 aaatgcagaa aataaatttg cactcactgg tacacctatg gaaaataatc tactagaatt
     2461 atggtctata tttgatttta taatgcctgg ctatctatat agtaaagcaa agtttcagga
     2521 attgtttata aataaagaag ataatgttaa aaacctgaaa aaattgataa aaccttttat
     2581 tcttagaaga agtaaaaaac aagttatgaa agaacttcca gataagattg aaaaaaactt
     2641 ttttgttgaa ttgaataaag agcagaaaaa gatatatagt gtatattcaa aagatataca
     2701 agataaaatg aaggataaaa atttaaagaa agataaaata gttatatttt cttatttaac
     2761 taaactaaga caactttgtt tagacccaag tatagtagta aaagattaca ataaaaaaag
     2821 ttcaaaaatt gaaacatgtt tagaaatact tagggatagt ataaacgaaa accacaaaat
     2881 attattgttt tcacaattta cttctgtgct taagaacata agtaaggaac ttgataagta
     2941 taaaattaaa taccattata tagatggtaa aactaatgcc aaagaaagac ttgaacttgt
     3001 agatgagttc aataatagta tggataaaaa agttttttta atatctttaa aagcaggcgg
     3061 aactggttta aatcttacat ctgctgacat ggtaattcac tttgacccat ggtggaatcc
     3121 atcagtagaa aatcaagcta gtgatagagc tcatagattt ggtcaaaaaa attcagtaca
     3181 agttataaaa ttgattgcta aagggactat agaagaaaaa ataataaaat tacaagaaag
     3241 taaaaaagag cttataaatc aatttataaa tggagaactt tctaatgaag gtgtattaaa
     3301 aagtctatct gatgaggaga taataaactt atttaactaa attatttaat cctacagctt
     3361 aactatataa atttgttcta acatttatat agttaagcta aaatatctga ataaataaaa
     3421 tttaatattg ttatttaatc ccaactttac aatctaatga tatctctttc tatacatatt
     3481 gcatatacaa atgtaataac ttgactatta gaatattttg ttttaacaat actatttcat
     3541 cataataatg aagtatatgt acactcactt ttgtaagttt tgcaatccat tttacagttt
     3601 tcattattgt aaattttggt taaattattc ctctaaaaat ttctttgcta catttgaaaa
     3661 atctaatcca ttcgataaaa ttgcaggatg accaccttta tcaaacaaat acattttacc
     3721 atttttaatc ttttcaagaa gtaatgaaaa agtattttca aaaaaatcac tagatattag
     3781 agatacaaac tcatcttctc tacttcctgt taaaagcacc tctggttgca tagtttctag
     3841 aggcttatga aaaaactttc ctatagtttt ataatgttca aaaatagctt ctgtatcatt
     3901 atctacaact ttttcccagt tttctccttg attataaata taaaaagctt ttgcaccatc
     3961 atcttgctta gatgcttcac gctctatttt cacattttgt acaaatgact ctagaggaac
     4021 ttctccttca aaactatctg caattacctt attcactaaa tcaggtctct caagtgcaac
     4081 atttaatgca acaagagcgc ctccactact accaattatg tttacttttt tatagttcat
     4141 tgcttctaaa aaacatatca cttgcatagc ctcatcaaac cataagtcag cagaaaattt
     4201 atcgaccatt tgagattttc catgacctac aaaatcaatt aatattactt tatattcatc
     4261 tttataaaaa tcgattatat cattaaacat cttggaagag gctgtatttc catgtaaaaa
     4321 aagtaatggt gtaccatccc caatttcatt atagtagcac tgtttgtcgt tatagttaaa
     4381 atatgccata tatttccccc ctttaatatc cctataggta tatatttatt acttatattt
     4441 aaaatgacta ttcccttagc cacttaaaaa tagtataact tagaatatag ataaaatcaa
     4501 cattccttgc taatttatct attgtttgtc taatttatta taatttaact tctgtaaaat
     4561 ttcttttttg tacgaaaata ttccttccat ttacaacaat cattcaaatg aagtataaca
     4621 tgacgagtag gaggcataag caaaattcca gcaatatctt tgttccccca aaagtccaac
     4681 aaccaaatag aatcttcatg ctttattact cctccagtca ccaaaatcct ttctaagtca
     4741 attggagaga cctttcgttt catatcttca gctttcaaat ccttaacaac ttctattgtg
     4801 ttttttgcaa cttcatttcg ataacaaagc aattcatcaa tattgactaa attatcgtat
     4861 atctcttttc actttaacca tttttttctt tataggtatc tccttatatt tttttaatat
     4921 caaatctccc ttataattta atatatctac atatgaacat aaatcttgaa cttcaattac
     4981 acctatatca tcattagtta taccttttat attactaaat gcaccaacta tatctaaaac
     5041 tcttattttc ttcttcttac cagcatttaa atataattta acaacttcac tttctatatt
     5101 tagttttata tctttacttt tgtaagaatt tttatcaact ttttttctct ttgatacttc
     5161 ttttagtact ccttttgaat attcttcaaa caaaactttg ccatgtgtaa ttctactttg
     5221 ttctatatct tttaattcat ttattttata tcctatatac gtttctatat tctctatata
     5281 tttttcatcc ttttcagtta ctatagtaat tgcctttcca ctatttcctt ttctcccagt
     5341 tctacctatt ctatgtatat agttttcttt atcttgtggc acatcatagt ttattactaa
     5401 agaaatatca tcaatatgta ttcctctgga cgctacatca ctactaacta atatattaaa
     5461 tttttggttt ttaaaatcct taattacaaa aattcttctt tcttgtgata aatctgcatg
     5521 taactctctt attaaaaaac cttctttact catcttatta tataatttag atactttctc
     5581 tttggtatta caaaatatta tcacactctt tggattttcg ctgtatatta attcttttaa
     5641 aaggatgtac ttctctcttc catttgcctt gattattttg tcatctattt gtcttgtttt
     5701 ttgattagta tcgctctcat tttcttctat atttataaca ctgtaatcta gcatatattt
     5761 ttcacatata tattttatct cttcatctat tgtagctgaa aaaagactta ctattttctc
     5821 cttaggtaaa tttaataata ttttttccat ttgttcaaca aaacctttat taaacatttt
     5881 atctgcctca tctattacta aatactttac attttccaac ttaatagaac ctctatttat
     5941 atggtcaagt attctgcctg gagtagctac aacaatatga accctttgtt tcaattcagc
     6001 tatttggtct tttatagatt gtttgccaaa tatagcacta catctcacct tctttagtct
     6061 ccctatatct gatatctcat cttttacttg caaggctaat tctcttgttg gaaccactat
     6121 aagagcttga acattattgt aatctacatt tatattctcg cataaaggta ttgcaaaact
     6181 tgctgtcttt ccacttcctg tttttgacct aactactaag ttttgacctt ttaataattt
     6241 tggaataact tctctttgta ctctagaagg tatattatat cctaaactct tcaatgactt
     6301 aagtatcttt tcatttaact taaatttttc aaatgtatat ttcatatatt accaccttat
     6361 tatatttatc ttatctatat atttttctac attatattat tataatacaa ggttctacta
     6421 tttttatatt atttattaga ctgaagataa aagtatatac tctataaacc tatagtttag
     6481 tagcaaatta attaaatttt tatatttaaa tacctcctta aatatactga taaatcaata
     6541 ttttcaagga ggtatctctt gtcaataatc aaactaatct atcttttgaa agtttaaatt
     6601 atactaatac attgtatttt tatttatatc taatattaaa aggtattaat caatacctaa
     6661 atcaccataa tctcacatat ttatatcttt attcaatata ccttctgtaa tcaatcgtgc
     6721 tatataatca taacctgatt catttgcttt gttacaatca ttcacattat cacagaaaaa
     6781 actttcaatc tgtattgcaa ctggatttgt atttctcaat atatataaat tttctctttt
     6841 tttagctcct ctattttcaa ataattctcc aagtctatta gatactcttt tagcatattc
     6901 taatccttca gtgccatagt aaagcacttc tgtaccacat tgtgttccat cagctttatt
     6961 taaatgtagc tctactaata aatcgtattt accactgttt acttttggaa ctctatagaa
     7021 aaattcttct ctttctgaca taaagtgcct ttctggacaa attattacat ctactgtatt
     7081 accttgactt ataagcatct cagctaacat aggagctaat tttttattat aattgtattc
     7141 atcaactata ccatttacac ctgtactttt accacctttt agtatactat gacctactgt
     7201 tatgcatatt ttcatttact tttttcacct tcttttaagc caatttttat ataatagtaa
     7261 tataatttta aagttattac taataataat atattaattg aagaaggtaa aagttctccg
     7321 tgattatcat ttt
//
LOCUS       DAMKNB010000133         7068 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.139, whole genome shotgun sequence.
ACCESSION   DAMKNB010000133 DAMKNB010000000
VERSION     DAMKNB010000133.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7068)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7068)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7068
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.139"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            complement(550..1956)
                     /locus_tag="PC494_003424"
     CDS             complement(550..1956)
                     /locus_tag="PC494_003424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF3913878.1"
                     /translation="MDSVKYILRRFIGSSILISLLFIVLNIAGFLLFSYMLFVSKYSD
                     NLDTSDSREIKSNLIMIEDNLILRNGKFILDDSSKEVLHKNKVWAMLIDNNGDRIWGF
                     DLPKEIPSHYTLTDVAKFSRFFLKDYPVYVWEHPNGILVTGYPKDKYTKFNLTYTVKE
                     IEQFPMLIIGMFLVNAIVTFLIALFIGLKMVKSIKPIITGIKLMSKGEPVLLQEKGIL
                     SDISKSINTVSKELQMKDEKLRKKEEARSNWIAGISHDIRTPLSMIIGYAGELEESSS
                     LSNREQEQVSIICNQGIKIRELVNDLNLVSKLEYNMQTLNCDKIRVSAFLRELISEFI
                     NNNLDNDFYVELDILNEDIIIDADKKLLKRAISNLIQNSITHNQQGCNIRVTSKSDLD
                     FCYIIVEDDGKGMSQERINSLLKGQNGLSEAYAKGQNHGLGILIVSGIINAHRGKLDI
                     TSIDSQGLKTILKLPLIK"
     gene            complement(2001..2708)
                     /locus_tag="PC494_003425"
     CDS             complement(2001..2708)
                     /locus_tag="PC494_003425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF3913879.1"
                     /translation="MESIKDKKILVVDDHKELLKMIDEILRKEGFSRVFLASSYEEAV
                     RVFRNVKPDCAILDVVLPDGDGFSIMRKIRETSKIPVIFLSARGEDEDRLIGLGLGAD
                     DYIVKPFLPKELTLRLVGILNRVYVPIEEEELPVFKLGDSVVVNLNSACVEKDGQEIS
                     LTAKEHSLLLKLYENKGRIVTNDSLCQAIWGDDMYGYENTLMVHVRRVREKIEKTPST
                     PKHLITVRGLGYKLMIN"
     gene            2879..3793
                     /locus_tag="PC494_003426"
     CDS             2879..3793
                     /locus_tag="PC494_003426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF3913880.1"
                     /translation="MEMIIRTQRLSKEYNKIFRVKDIDLRVPQGAVYGFLGPNGAGKS
                     TTLKMLLGLAKPTQGNINILGKELNEKNRISILKDIGSLIESPSYYGHLTGLENMTIM
                     QRLLDLPEKNVNEALKIVRLENQKNKKVSQYSLGMKQRLGIAMAIMKFPKLLILDEPT
                     NGLDPAGIEEIRELIKSLPEKYGMTVLISSHLLSEIDQIATSIGIINHGELVFQDSIK
                     ELHNRGQSQIAIKTKNVVSAQKLLNTKGYMSLIQDGYLTIENLKDSDVAKINGMLVHS
                     NIDVFRIEEHKKSLEDIFLELTGKAVTL"
     gene            3793..4554
                     /locus_tag="PC494_003427"
     CDS             3793..4554
                     /locus_tag="PC494_003427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF3913881.1"
                     /translation="MKYLGLEFYKLKRKKIILMTFLFVAVEIMWCIINSNRAITRNPD
                     MLGGFEYSYMLMSFASLNGLFFPILISIITSRISDIEHKGDTWKLLKSSVTSLNSIYL
                     SKFLCSAILVSIPVLMQVLSIVLFGHFRGVIESISVSLLLKYTLGTILVSIAIIALHL
                     WIATVIPNQMIAITFGMIGSFIGLTSGLFYQGIRRLFIWSYYLELSPLSYAYDNVLGS
                     SVYRIDMNFSITILVFLIGMLIYYIGRNHLLKKEV"
     gene            4566..5303
                     /locus_tag="PC494_003428"
     CDS             4566..5303
                     /locus_tag="PC494_003428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF3913882.1"
                     /translation="MLRKSVLGEILKLKNSFIWYVLLALPLISVLIGSGNFYLNQGIL
                     KKEWYSLWTQVSLFYGEFFFPILIAIFCAYICRLEHMNHNWNNVMTLPVNLKNIFLSK
                     LTVVSILTAITQVFFVIFYIVAGNMFGFSGSVPKELTGWIAKGWIISISIASIQLYMS
                     IKIRSFATPIGISLCLSLFGMGLIVAKPAVGIFFPYSMLGSAMGVIKQSALNVNDTIV
                     TICVAFITTIVFSEIANRNFRKNDVIS"
     gene            6181..6450
                     /locus_tag="PC494_003429"
     CDS             6181..6450
                     /locus_tag="PC494_003429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3795 domain-containing protein"
                     /protein_id="HDF3913883.1"
                     /translation="MFESRCGVCCDSCTKKEQVNCTGCPTMEKPFWGGECKVKTCCES
                     KELNHCGECDTFPCDMLLNKGKDQGFDPMVNIEQCRKWLEETVSN"
     gene            complement(6668..6913)
                     /locus_tag="PC494_003430"
     CDS             complement(6668..6913)
                     /locus_tag="PC494_003430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Pathogenicity locus"
                     /protein_id="HDF3913884.1"
                     /translation="MGELQKIPGVGKATEKSLIMLGYTTIKLLKDANPAQMYEKECLM
                     RGQHIDRCQLYVYRCAVYFASTENPEPEKLKWWYWKD"
BASE COUNT         2455 a         1014 c          927 g         2672 t
ORIGIN      
        1 tacatatata tatatgttat ttctaaaaat actacacaaa aactctactt tagtagaact
       61 taatggcgca aaatacttca atttaaaaca tttatcgtac tttaaataaa taactataat
      121 aatatactta caatagttac atagaagcta ttataactac acagaacagc gtataattaa
      181 aactttttta ggatgtcatt atattttttc ttaaaattaa aaaacactat accataattc
      241 tattttagta gaattttttt gtcaataata aaattaaata ttaactaaaa aataaaaaaa
      301 atggaattat ctaaagaatt taataacctt acaataattc caaaatatta tttctatgaa
      361 aattttgata ccatgagtaa ctcagccata agcgcataaa gcacaagtta ctctttactt
      421 taataaaact tgacaagaaa agaatttatc cttattctac tctaatagag ttaatttgtc
      481 aataaagaat aaaattattt tcaaaatatt ttcattcttc attcttatct gttattattt
      541 tataaaatat cacttaatta gaggtaattt tagtattgtt tttagtccct gactatcaat
      601 gctcgtaata tctaatttac ctctatgtgc attaataatg ccagatacta tcaaaatacc
      661 tagaccatga ttttgacctt tggcatatgc ctcacttagt ccattttggc cctttaataa
      721 actattaatt ctttcttgac tcataccttt tccatcatct tcaacaatta tatagcaaaa
      781 atctaaatca gacttagagg taacccttat attacatcct tgttggttat gagttatact
      841 attttgtatt aaattactaa tagccctttt taataatttt ttatctgcat ctataataat
      901 atcttcattt agtatatcaa gttcaacgta aaagtcatta tccaaattat tatttataaa
      961 ctcagaaata agctctctca aaaacgcaga aactctaatc ttatcacaat tcaatgtttg
     1021 catattatat tcaagtttag acactaaatt gaggtcattt actaattctc tgattttaat
     1081 cccttgattg catataatag acacttgctc ttgttctcta tttgaaaggc tactgctttc
     1141 ttcaagttct ccagcatatc caattatcat tgaaagtgga gttcttatat catgagatat
     1201 tcctgcaatc cagttagacc tagcttcctc tttcttccta agtttttcat ctttcatttg
     1261 caactcttta gatacagtat taatagattt tgaaatatca cttagtattc ctttttcttg
     1321 taaaagtact ggttctcctt ttgacataag ctttatgcca gtaataattg gttttataga
     1381 tttcaccatt tttaaaccta tgaatagagc tattaaaaaa gtaactattg cattaaccag
     1441 aaacatacct attattaaca taggaaattg ttctatttcc ttaaccgtat aagtaaggtt
     1501 aaacttagtg tacttgtctt ttggataacc tgttactaat attccatttg gatgttccca
     1561 tacatacaca ggatagtcct ttaaaaagaa ccttgaaaac tttgctacat ctgtcaaagt
     1621 ataatgactt ggaatttctt ttggtaaatc aaatccccat attctatctc cattgttatc
     1681 aattaacatt gcccaaactt tatttttatg tagtacttcc ttactagaat catctaaaat
     1741 aaactttcca tttcttaaaa tcaaattatc ttcaatcata atcaagtttg attttatttc
     1801 tctgctatca cttgtatcta aattatcaga gtatttagat acaaatagca tatatgaaaa
     1861 cagaagaaaa cctgctatat ttaatacaat aaaaagtaat gaaatcaaga tacttgaacc
     1921 tataaatcgc ctcaatatgt actttacact atccaaaatt aaatcactcc tcttgatttc
     1981 ttttattcta atatctaaaa ttaattaatc atcaacttat atccaagacc tcttactgta
     2041 ataagatgtt taggtgtaga tggagttttt tctatcttct ctctaactct tctaacatga
     2101 accataaggg tattttcata tccatacata tcatctcccc aaatggcttg acatagtgaa
     2161 tcattagtaa caattctccc tttattttca tacaacttta aaagcaacga atgctcttta
     2221 gctgttaaag aaatctcttg cccatctttc tcaacacatg cactatttaa attcacaaca
     2281 acagaatctc ccagtttaaa tactggcaac tcctcttctt ctataggcac atatacacga
     2341 tttaatatac ccacaagcct taaagtaagt tcctttggta aaaatggctt tactatataa
     2401 tcgtcagccc ctaagcccaa accaatcaat ctatcttcat cttcacctct tgcagagaga
     2461 aaaatcactg gtattttaga tgtctctcta atttttctca taatagaaaa accatctcca
     2521 tctggcaata caacatctaa aattgcacaa tctggcttta catttctaaa taccctaaca
     2581 gcttcctcat aacttgatgc taaaaatact ctactaaacc cctcttttct caggatttca
     2641 tctatcattt ttaataattc cttgtggtca tcaaccacaa gtattttttt atcttttatt
     2701 gactccataa tcatcaccct cctttagtat accatatacc cattttcaca actttgccta
     2761 aatagacttt taaggttatt gtaaggtaaa tttcagctaa ttgaaatgta accaagttat
     2821 tatactgata taagttaaaa gaatcaataa gcacagatta aaaaagggga tgaaacatat
     2881 ggaaatgata attagaacac aaagactttc aaaggaatac aataaaatat ttagagtaaa
     2941 ggatatagac ctaagagttc cacaaggagc tgtatatggt tttttgggtc ctaatggagc
     3001 tggaaaatct accactctta aaatgcttct tggacttgct aaacccacac aaggaaatat
     3061 taatatttta ggtaaagagt taaatgaaaa aaatagaata tcaattttaa aagatatagg
     3121 ttctttgata gaatctccat catactatgg tcatcttaca gggcttgaaa acatgaccat
     3181 aatgcaaaga ctcttagatt tacctgaaaa aaatgtaaat gaagcattaa aaattgtaag
     3241 gttagaaaat caaaaaaata aaaaagttag tcaatattct ttaggtatga agcaacgtct
     3301 tggcattgct atggcaataa tgaagtttcc caaattatta atacttgatg aacctacaaa
     3361 tggactcgac ccagcaggga ttgaggaaat tagagaatta ataaaatctc taccagaaaa
     3421 atacgggatg actgttctaa tctctagcca tcttttaagt gaaattgacc aaattgccac
     3481 atcaatagga ataataaatc atggcgaact ggtttttcaa gatagcataa aagaacttca
     3541 taatagaggt caaagtcaga ttgctatcaa aactaagaat gttgtatctg cacaaaaact
     3601 attaaatact aaaggatata tgtcacttat acaagatggg tacttgacta ttgaaaattt
     3661 aaaagactca gatgtggcta aaataaatgg tatgcttgtc cattcaaata tagatgtatt
     3721 tagaatagaa gaacataaaa aaagcttgga agatatattc ttagaactta ctggtaaggc
     3781 ggtgacttta taatgaaata ccttggtcta gaattttata aacttaaaag aaagaagatt
     3841 attctgatga cctttttatt tgtagctgtt gaaataatgt ggtgtatcat aaattcaaat
     3901 agagctatta cacgtaatcc agatatgtta ggtggatttg aatattccta tatgcttatg
     3961 agttttgcaa gtttaaatgg tctattcttt cctatcttaa tatcaataat tacatcacgt
     4021 ataagcgata tagaacataa aggagataca tggaagcttt taaaatcttc tgtgacatct
     4081 ttaaatagta tttatttatc taaattttta tgttctgcta ttttggtatc tatacctgta
     4141 ttgatgcaag tgctatctat tgtgttgttt ggacatttta gaggggttat tgagtcaatt
     4201 tctgtatctt tacttttaaa atacacatta ggaacaattc ttgtaagtat tgctatcatt
     4261 gcactacacc tatggattgc aactgtaatt ccaaatcaaa tgattgcaat tacatttggc
     4321 atgattggta gttttatagg tttgacatca ggtttgtttt atcaaggtat tcgtagattg
     4381 tttatatggt cttattacct agagttatca cctttaagtt atgcttatga taatgtttta
     4441 ggttcatctg tctatagaat tgatatgaat ttttctatta cgattttagt tttcttaatt
     4501 ggaatgctaa tttattatat tggaagaaat catttattaa aaaaagaagt ataggaggga
     4561 tttaaatgtt aaggaagtca gttttgggag aaattctaaa gttaaaaaat tcttttatat
     4621 ggtatgtatt attagctttg ccacttataa gtgtgttgat tggttctggt aatttttatc
     4681 taaatcaagg catactcaaa aaagaatggt acagcttatg gactcaagtt agtctttttt
     4741 atggggaatt tttctttcct atcttaatcg caatcttttg tgcatatatt tgtaggcttg
     4801 aacatatgaa tcataattgg aataatgtaa tgacactgcc agttaattta aaaaatatct
     4861 ttttatctaa acttacagta gtttcaatac ttacagctat tacacaagtt ttctttgtta
     4921 tcttttatat agttgcagga aatatgtttg gtttttctgg tagtgtacct aaagaattga
     4981 ctggttggat tgctaaaggt tggattattt ctatttcaat agcttctata caattataca
     5041 tgtctataaa gattagaagt tttgcaactc ctattggtat tagtctttgc ctttctctat
     5101 ttggtatggg attaatagta gcaaaacctg ctgttggtat atttttccct tattctatgt
     5161 taggtagtgc tatgggggtt ataaagcaat ctgctttaaa tgttaatgac actatagtta
     5221 caatatgtgt tgcatttatt actactatag tattttctga aattgccaat agaaatttta
     5281 gaaagaatga tgttatttct taatggtaaa tgctagatat tttggggttt gaaatttata
     5341 ttctttttag ttgaaatcta tatccatttt atttaaaaat atatatcttt tatttgaatt
     5401 ttatatgttt tatctactcg ctatataata gatatactcc taaaattaaa aaatatataa
     5461 taatgttatt atttaaaatt attatgtatt atattaaaac ttaatgcaaa aacaattttt
     5521 atattatata atgaaactta attgaatata ggtaaaaaat cattcaatat attaaataaa
     5581 tatttaactt taataatcta tatttaatta tagctataac atagaattat caaatatatt
     5641 gaatgaatat ttgactcttg gaatgtgtaa ttaaattaag tttggttatt cgatggaagg
     5701 caaatttgat ataaaactcc atttaaagtg ccagataaaa actttatggt tatataaaag
     5761 ttaaaagtaa tttatagtgt tatagaatat tcaaagggat ttaaagtaat ctatggtgtt
     5821 ttgaaatatt caaagggatt taaactaatc tatagtcttg tagaatattc aaagagattt
     5881 aaaacaatct ataatgttgt aaaatatatt caaagggatt taaactaatc tatagtcttg
     5941 tagaatattc aaagagattt aaagcaatct ataatgctgt aaaatatatt caaagggatt
     6001 tgaagtaatt tattgtgttt tgaaatattc aaaaagattt ttggaatagt ttttataaat
     6061 ttaccagtac taataatttt atgtttaaca tttagatgac ctaaaatcaa ctatttgcac
     6121 ttttgtattc atctaaaatc attttataat atttttaaat aatggaaagg atgtttgaac
     6181 atgtttgaat caagatgtgg tgtctgttgt gacagttgta caaaaaaaga acaagtaaat
     6241 tgcactggtt gcccaactat ggaaaaacca ttttggggtg gagaatgtaa ggttaaaact
     6301 tgctgtgaaa gtaaggaact taatcattgt ggtgaatgtg atactttccc ttgtgatatg
     6361 cttttaaata agggaaaaga ccaaggtttt gaccctatgg taaatattga gcaatgtaga
     6421 aaatggcttg aagaaacagt ttctaattaa ttgttttaga atgctttgtt aagtaattta
     6481 tttaatcctt tgttaggtag tatgtttagt catttgttga ttggtatatt tatacattta
     6541 ttgatgggta tatttagcca tacaaataga tttacataaa atttacgact aaaaaagagt
     6601 tgagtattag tttttattat ttaaaacgga tattcaactc ttttttatgt ctaacttttt
     6661 tgatttttta atctttccaa taccaccact ttaatttttc tggttctgga ttttcagttg
     6721 atgcaaaata tactgcacat ctgtatacat ataactgaca tctgtctatg tgctgtccac
     6781 gcattaaaca ttccttttca tacatttgtg ctgggtttgc atctttaagt aatttaatag
     6841 ttgtatatcc taacatgatt aaagattttt ctgttgcttt ccctacccct ggaatttttt
     6901 gtagttctcc catacttcac cttctttctg gtatattctt tttatattat acctattacc
     6961 agatattttt ttattatagt taatatttaa tatttaattt tttattatat caatttattt
     7021 atgctctttc atatatatat attttaccac ctctaaatca ctgagtca
//
LOCUS       DAMKNB010000134         7021 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.140, whole genome shotgun sequence.
ACCESSION   DAMKNB010000134 DAMKNB010000000
VERSION     DAMKNB010000134.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7021)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7021)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7021
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.140"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            143..1036
                     /locus_tag="PC494_003431"
     CDS             143..1036
                     /locus_tag="PC494_003431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HDF3913885.1"
                     /translation="MQLYNTPFNTNKHLIYFFTFTLVLNWIFSLTPALLGITNTILGE
                     IIFYLAYTSPAIVGLFFISTIYPQSAKQDFIYRYLSFKEIRIKWILLTILFFALTFIT
                     SLIIGNYFNVKTSDIDWIHIAVFRPSKIAYMLLASFILSILSQEAGWRGYAIDKLLVR
                     FGFIGSSIILGLVCGIWYLGSYFTPNQIPYNLAQYSLFDAFLFIPNIVLLNFIINFVY
                     INTSRSILSAGLVHMMYYFFNIQLLLHYPIKLCVIAQYVQIIFGLIFLVYMISSNKFK
                     QKVNSEIEQIKSDDFEFELDW"
     gene            1214..2038
                     /locus_tag="PC494_003432"
     CDS             1214..2038
                     /locus_tag="PC494_003432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HDF3913886.1"
                     /translation="MFKIGEVSKLTQISIRMLRYYDELGILKPAEIDKYTGHRLYSVE
                     QISILQRIVLLRDSKFSVAEIANIVHNWNDEFVIKELNRKKNEIQKEINQEQQRINKI
                     DKFIEAINCDKDEIHYNVVFKKIPSYKIISLREIIPDYQSEGILWEKLSKFIKEEHIE
                     VSRQSNNNIAFYHDEEVKDNGVDIEVGMVVKKIGKNKSGFIYRETEEIDMMACTMVYG
                     PYENIAGAYESFCYWLDKNSDYQISGINRQIGHKGEHNEINPENYLTEIQIPLIKV"
     gene            2137..2745
                     /locus_tag="PC494_003433"
     CDS             2137..2745
                     /locus_tag="PC494_003433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDF3913887.1"
                     /translation="MGKLLRGKIMKSDSTKEQLINATIQLLSSHRDVSSITAREIVAK
                     ANVNLAMINYYFKSKEELINISIKKFLKRHMDEYKATHDTKNLAPKQQLREILIAFFD
                     FIGEHSQFIKISVPYILIQEEIVYPFEILPLIKAHYENQNNKKTEAEYRTIAYQITSF
                     IQLLFLRSNAFFKYSGIDILNIEQRNGLIDFQLDLLLVDITK"
     gene            2849..3025
                     /locus_tag="PC494_003434"
     CDS             2849..3025
                     /locus_tag="PC494_003434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3913888.1"
                     /translation="MFFTFIGVISAILLLCTIICGLWIKLNNRNNDSNSHFTFSILSI
                     AFSLLIVVAFLVRN"
     gene            4133..4885
                     /locus_tag="PC494_003435"
     CDS             4133..4885
                     /locus_tag="PC494_003435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF3913889.1"
                     /translation="MLKVNQLCKSYKTGSKTYPVLKNISFEINKGEFVAIMGSSGSGK
                     TTLLNCISCFIPIDNGEIILGNNNIRNLKEKELSEVRNQQLGFVFQDFMLFDGLSVFE
                     NICVPQIIKGSQVLQMENRAINLCELFGIEHIRKKYPAEISGGEKQRTAVARALMNNP
                     DLILADEPTGNLDSKSCRTVIESFLKAKQELDATILMVTHDSFAASFCDRVIVLKDGI
                     IYKEVVKSNSRHKFLDELLEVLKEMGGAQDDN"
     gene            4875..6986
                     /locus_tag="PC494_003436"
     CDS             4875..6986
                     /locus_tag="PC494_003436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF3913890.1"
                     /translation="MTINKLYSKLRAYNWKNYTTLFFCIILSVVLVTSYALIYFSPTI
                     QNILPTGGDSRKQATMIFSVAILGCAVFTTYASSLFLKFKSKEIGIFMALGTDKKKLK
                     KLLFSEILLISIVCCFLGLILSIPVSFGIWKIFQLVIIDTREMTYHFGTQGFIYGFIF
                     SVFVTLCIFILSVKFINRTNIIDILNDQRISEPIQDVKDWYGILGIIFIILGIFLGYL
                     VPSLTINKLNYRLPSVWSFTYLLSLIGIYMIMTYIVVHAKRGKHPEKYYKNIISTSMM
                     RFMGRQTVKNMCVISFLIAGALFAVFYVPNMVTGIYDTLKNNPIDYTFTYNQRDKQVS
                     KKDIEQLADKHNIKIQNYMEIPSIELIVDGVESIYHKDGTIEKVYMKKSSYDMFFNSK
                     DFSKLIGKPITIKNGEYLAVVNKGNENQDYKYTKFISSPVTEKEIPFRYAGKIIFNGS
                     FFQNRSMNAYVLNDEDYKSFTKDLSIKNYNNSILFNVDKDTYAFANDLKKEIIKRTSK
                     EMGMFSGYDEYVKKRYESTGRKYFMDEEYPSGEGHLKLDPNNNQLYLNWKYYPNFKIL
                     QSQDMIKNMAVFLMLFIYVAIICFTAVGIIAYTRGVTIAINHKQVFMDLNRLGANNDY
                     IKFCIRNQLKKVFSYPLIAGSFLIYLFNFMIMLNNDGRIVNSEVNALLINLGFIGICG
                     VYMYLIYLLTYKKFKKIIGIL"
BASE COUNT         2633 a          921 c          937 g         2530 t
ORIGIN      
        1 aaaaataatt aatcaaaata taaaaaatag gatattatta taggcaataa ctaacatcaa
       61 gcgataactt aatacatata aaaataaata aacaattaat aaaaattaaa acttcattat
      121 aaaacggaag gatagtgaaa aaatgcaact atataacacc ccctttaata caaacaaaca
      181 cttaatctat ttctttacat ttacgctagt attgaactgg atattcagtc ttacacctgc
      241 gttgctcgga attacaaata caatacttgg agaaatcatt ttttatcttg catatacatc
      301 accagctatt gtaggtctat tttttatttc tacaatctat ccacaaagtg caaaacaaga
      361 ttttatttat agatacctaa gctttaaaga aattagaata aaatggatac tattaacaat
      421 attatttttt gctttaactt ttattacttc gttaataatc ggaaattact ttaatgtaaa
      481 aacttctgat atagattgga tacacatagc agtgtttaga ccttctaaaa tagcttatat
      541 gctattagca agttttatat tgagtatact tagtcaagaa gctggatgga gaggatatgc
      601 cattgacaaa ttattagtta gatttggatt tataggctct tcaattattt tagggcttgt
      661 ttgtggaatc tggtatctag ggtcgtattt tacacctaat caaataccat ataatttggc
      721 acaatactcc ctatttgatg cttttttatt tataccaaac attgtacttt taaactttat
      781 aattaatttt gtatatatca atacaagtag aagcatttta tcagctgggt tagttcatat
      841 gatgtactat tttttcaaca ttcaattact tctacactac cctattaaat tatgtgtaat
      901 agctcaatat gtacaaataa tatttggttt aatatttctt gtatatatga tttcttctaa
      961 taaatttaaa cagaaggtaa attctgaaat tgaacagata aagtcggatg attttgaatt
     1021 tgagttagac tggtaatttt aatatgaatt ataaattaag ataatctatg atttgatacg
     1081 attactactt aaatataatt tactctctat aatttattgc aacatctgga aaataattgt
     1141 atttccacaa acgcttgaag tatataaaaa caaaatatat actgattata agtgaaaagg
     1201 aggtcatatt ttcatgttta aaataggaga ggtttcaaaa ctaacacaaa tttctattcg
     1261 tatgttgcgt tattatgatg aacttggtat tttaaaacct gcagaaatag acaaatatac
     1321 aggtcataga ttatactcag ttgaacagat ttcaatacta caaagaattg tattattgag
     1381 agattcaaaa tttagcgttg cagaaatagc aaatatcgta cataattgga atgatgaatt
     1441 tgtaattaaa gaattgaata gaaaaaagaa tgaaatacaa aaggaaataa atcaggaaca
     1501 acaaagaata aataaaattg ataaatttat agaagctata aactgtgata aagatgaaat
     1561 tcattacaat gttgtcttta aaaagattcc aagttataaa atcatatcac ttagagagat
     1621 aattccagac taccaatctg aaggtatact ctgggaaaag ctatctaaat ttatcaaaga
     1681 agaacatata gaagtatcac gtcaatccaa caataacata gctttttacc atgatgaaga
     1741 agtcaaagat aatggtgtag atattgaagt tggaatggtt gtaaagaaga ttggaaagaa
     1801 caaatctgga tttatatatc gtgagacaga agaaattgat atgatggcat gtactatggt
     1861 ttatggtcca tatgaaaata tagctggtgc atatgaatcg ttctgttatt ggttagataa
     1921 aaatagtgat tatcaaatat caggtataaa tagacaaatc ggacataaag gtgaacataa
     1981 tgaaataaat cctgaaaatt atcttacaga aattcaaatc ccccttataa aagtctaata
     2041 gattagtact taaatactta agtactaatc acccattgac atcccaaaat tttcatgata
     2101 gtatctaaac gtgtgttaaa catgtttaat ttttttatgg ggaaactttt aaggggaaaa
     2161 attatgaaat cagattcaac aaaggaacaa ttaattaatg ccacaatcca gttactatct
     2221 tcacatagag atgtttcaag cattacggct agagaaattg tagctaaagc aaatgtcaat
     2281 ttagctatga ttaattatta ttttaaatct aaagaggagt taattaatat ttctattaaa
     2341 aaatttttaa agcgtcatat ggatgaatat aaggctacac atgatactaa aaatttagca
     2401 cctaaacagc aattaaggga aatactaatt gcattttttg attttatagg tgaacatagt
     2461 caatttataa agatttctgt accctatata ttgatacagg aagaaattgt ttatccattt
     2521 gagatactac ctttaattaa ggctcactat gaaaatcaga ataacaaaaa aactgaagct
     2581 gaatacagaa ctattgcgta tcaaataact tcatttattc agttgctttt tcttcgttct
     2641 aatgcttttt tcaagtatag tggtattgat attcttaata ttgaacagag aaatggttta
     2701 atagattttc aattagattt attattggta gatattacaa aataatacta tattaatttt
     2761 ttatgtacat ttttttattt tatggtaacg tttgaaaata ttctcattga ctaaaaatac
     2821 ttgcattaaa taagggggag gaattttaat gttttttaca tttataggag taatatcagc
     2881 aattttattg ttgtgtacaa ttatatgtgg tttatggata aaacttaata atcgtaataa
     2941 tgactctaat tctcatttta ctttttcaat actttcaatt gctttttcac tgttaattgt
     3001 ggtggccttt ttagtaagaa attaatgtct ttgttatgct gaggtttatt attatagatt
     3061 tttattattg catgattttt actatattat agtattttta ttatattaca gggtcttatt
     3121 tattatagtg ttttgttgtt acagcatttt attatattac agagtcctat ttattatagg
     3181 atttttatta tattgtaaaa tcttatttat tataggattt tgttatatta caatctctta
     3241 tttattgcag tgtttctatt atattgcaaa ctcttattta ttatggtgtt ttgttattgc
     3301 aacatttcta ttatattgta aagtcttatt tattacagtt ctttattaca ctacagactt
     3361 ttattattac aatctcttat ttattacagt tctttattat actacagact tttattatta
     3421 cagcatttct gttacattgc aaagtcttat ttattacagt tctttattat actacaaacc
     3481 tttattatta caacatttta ttattttaac ttctttacta taatatagta atattttaat
     3541 atctcaaaat aatatcaatc acttttcagc atagtctaaa atacttccac tttctaaaat
     3601 tatctatcat acctatacta ataatacttt tcaacctttt tattataaat ttcaattgtt
     3661 tttaacaacc tatttatttc caaaactcca atatattttc tcaattacat tgtgttaata
     3721 acccctaaat cctttcaaat tatttacaat acattccatt aaataatctt actgctctat
     3781 aattcttttt ttctttttaa ccctactata cattatttac atcatttttt tcaatacaac
     3841 attcgttatt ctataacctt tttactttta ctatatacct tttttctaac tacaccttca
     3901 atgttccaca tcatattact ttaccacaac aattaatacc taaaaataac cctctaaatc
     3961 ctccaataat ataatcaatt taactataat aataacctct cacactatcc aaacaatata
     4021 ttttcaaaca ttacaaaaaa acatccaact attacaatat agctcatatc cctcctcccc
     4081 tttcaaatgc tatcattgac ttacaagata aatgaaagtg aggatgatat atatgcttaa
     4141 agtaaaccaa ttatgtaaat catataaaac aggtagtaaa acatatcctg tattaaaaaa
     4201 tatttctttt gaaatcaaca aaggagaatt tgtcgcaatc atgggttcat caggaagtgg
     4261 aaaaactact cttttaaatt gtatttcatg ttttatccca attgataatg gggaaataat
     4321 tcttggaaat aataatataa gaaatttaaa agaaaaggaa ctttcagaag ttagaaacca
     4381 acaactagga tttgtattcc aagatttcat gctatttgat ggtcttagtg tctttgaaaa
     4441 tatatgtgtt ccacaaatta tcaaaggtag tcaagtctta caaatggaaa accgtgcaat
     4501 taatctatgt gagctatttg gtattgaaca tatcagaaaa aaataccctg ccgaaatatc
     4561 tggtggagaa aaacagcgta cagcagtagc aagagcactc atgaacaacc cagatttaat
     4621 attagcagat gaaccaactg gtaaccttga tagtaagtct tgtcgtacag tcattgaatc
     4681 atttttaaaa gcaaagcaag aattagatgc tactatactc atggttacac acgatagctt
     4741 tgcagcaagc ttctgtgacc gagttattgt gcttaaagat ggaataattt ataaagaagt
     4801 tgtaaaatca aattcaagac ataaattcct agatgaatta ctagaagttt taaaagaaat
     4861 gggaggcgct caagatgaca attaataaat tatacagtaa acttcgagcc tataattgga
     4921 agaactatac aactttattc ttttgtataa tactttctgt ggtattagta acttcatatg
     4981 ctctaattta ttttagccca acaatacaaa acatacttcc aactggtgga gatagcagaa
     5041 aacaggctac aatgatattc tcagttgcta tattaggatg cgctgtcttt actacatacg
     5101 cttcttccct ctttttaaaa tttaaaagca aggaaattgg tattttcatg gctctaggaa
     5161 cagataagaa gaaattaaaa aaacttctat tttcagagat attgttaatt tcaatagtat
     5221 gctgtttttt aggtcttata ttaagtattc ctgtatcttt tggtatatgg aaaatatttc
     5281 aattagtgat tattgatacc agagaaatga catatcattt tggaactcaa ggattcatat
     5341 atggatttat atttagtgta tttgtgacat tatgcatatt tatactttct gtaaaattta
     5401 ttaatcgtac aaatataatt gatatattaa atgaccagag aatatctgaa ccaatacagg
     5461 atgtaaagga ctggtatggt atattaggta taatttttat tatactcggt atttttctag
     5521 gatatctcgt accttcacta actataaaca aattaaatta tagactacca tctgtatgga
     5581 gctttactta tctactctct cttattggaa tatatatgat tatgacatac atagttgtac
     5641 atgctaaaag aggaaaacat ccagagaaat actataaaaa catcatatca actagcatga
     5701 tgagatttat gggaagacaa acagtaaaaa acatgtgtgt tatttcattt ttgattgcag
     5761 gagcattatt tgctgtattc tatgttccta atatggttac aggtatctat gatactctta
     5821 aaaataaccc tatagattat acttttacct acaatcaaag agataaacag gtatcaaaaa
     5881 aagatattga acaattagca gataaacaca atataaaaat tcaaaactat atggaaattc
     5941 cttctataga attaattgtt gatggtgtag aatcaatata tcataaagat ggaactatcg
     6001 aaaaggtata tatgaaaaaa agctcctatg atatgttctt taattctaaa gatttttcca
     6061 agctaattgg caaaccaata actataaaaa atggtgaata tcttgctgtt gtaaataaag
     6121 gaaatgaaaa tcaagattat aaatatacca aatttatatc aagcccagtc acagaaaaag
     6181 aaatcccctt tagatatgct ggaaaaataa tatttaatgg ttcttttttt caaaatagaa
     6241 gtatgaacgc ctatgtcctt aatgatgagg attataaatc atttactaaa gatttatcca
     6301 taaaaaatta caataattct atactattta atgtagataa agatacctat gcttttgcca
     6361 atgacttaaa gaaagaaatt ataaaaagaa catctaagga aatgggcatg ttcagtggtt
     6421 atgatgaata cgtaaaaaaa cgttatgaat caactggaag aaaatatttt atggatgaag
     6481 aatatccaag tggtgaaggt catttaaaac tagacccaaa caacaatcag ttgtatctta
     6541 attggaaata ctatcctaac tttaaaattt tacaaagcca agatatgata aaaaacatgg
     6601 cagtcttctt aatgttattc atatatgtgg caatcatatg ttttacagca gtaggaatca
     6661 ttgcatatac aaggggtgtt actatagcta taaatcacaa gcaggtcttt atggatttaa
     6721 atcgattagg agcaaacaat gattatataa agttctgtat tagaaatcaa ttaaagaaag
     6781 tattttcata ccctcttatt gcaggaagtt ttttaattta tctgtttaat tttatgatta
     6841 tgttaaataa tgatggtaga atcgtcaata gtgaggtcaa tgctcttttg ataaacttag
     6901 gttttatagg gatttgtggg gtttatatgt accttatata tctattaact tataagaaat
     6961 tcaaaaaaat tattggtatt ttataataaa aaaggttatt agatttttaa agtaataaaa
     7021 t
//
LOCUS       DAMKNB010000135         6587 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.141, whole genome shotgun sequence.
ACCESSION   DAMKNB010000135 DAMKNB010000000
VERSION     DAMKNB010000135.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6587)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6587)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6587
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.141"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            111..1853
                     /locus_tag="PC494_003437"
     CDS             111..1853
                     /locus_tag="PC494_003437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M3"
                     /protein_id="HDF3913891.1"
                     /translation="MVKSKKKIFVFLILIAVFIIFASYIRNYTNDTKKDSVRGTIPFE
                     KMEYKRPNIQSICENINKCNDKLLTAKTAKEQLNLFNEVDKIYQDFYSTLTIAKIRNN
                     IDSSDEFYSKEYKYLMSKSVDVDMSYKDFQDRFVTSKFSKELEKELGNDTFNYLKNIG
                     KLNSKEVEGLLKKEQDLVVKYEDLLAKSTVSIDGIEVDFEEALSRPNLSPEEYVKIYS
                     DYLKKYNPIFGNIFLELIQTRTEIASKQGFKNYIDYAYMNLNKDYSQEEAKKFRQDVK
                     DYIVPLYREISSKPSDSSIYIKVYKNRSFRKFDKVLEDISPKLKESFDYMKKYDLYDY
                     SSGKNKSPGGYTTYINKYKAPFLFNTWDNSFLGVTSFAHEFGHFYNYYNSINLNNKMQ
                     PSIDVCEVHSTSLEILFYKYFDDFFGKQSEAIKKEHLSIVLNTIIDACLYDEFQEIIY
                     KNPYMSLNDINKLFFDLEEEYGVSNNILREKNAPFWILVSHNFQVPFYYLSYGLASDV
                     SLQIWQLSQEDYRKAVDVYMDFLNQNTDAGFKDVVEKVNLQLPFQNGNLEEISSTLYD
                     YFGIDNPLELKNAS"
     gene            complement(2017..2211)
                     /locus_tag="PC494_003438"
     CDS             complement(2017..2211)
                     /locus_tag="PC494_003438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3913892.1"
                     /translation="MKIITIGSSLITVLLFLSTMVCGFWIKNNKVTDASSIKFHMNSA
                     IFTGIFLLISTILLIIYIKK"
     gene            complement(2208..2789)
                     /locus_tag="PC494_003439"
     CDS             complement(2208..2789)
                     /locus_tag="PC494_003439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDF3913893.1"
                     /translation="MKSNDKDARERIIEVTLNLLNEVDDIEEITVRKIAERANVGVGL
                     INYHFKTKDNLLSTAIGDVMSNIIAELYDDSVYTLRPIEDLKNLLKKLCDTGLHYEKV
                     LPFVLNQCITNGDMQAELDIVPMLRKIFGNKKDEMSLRIIALQIILPIQISALSTESF
                     QLYSGINIKNKYERDKFIDILIENIIGEDVDVR"
     gene            2957..3775
                     /locus_tag="PC494_003440"
     CDS             2957..3775
                     /locus_tag="PC494_003440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HDF3913894.1"
                     /translation="MFKIGDFSKLSKISIRMLRHYDEIGLLTPSHTNKTNGYRYYSAD
                     QLSTTNRIHALKDMGFGLYSIKEILTEYNDKESLIKYLNIHHSQVKEQLEDTQKKLLK
                     IETTIKRIGGNDIMKNYDVTIKNFAPKYMMTLRRVIPTYQDEGMLWHQAFLETKDQNV
                     QIEPPKYSKTVFYDTGYKEDYVDVEVQVAVSGKYKDTEHVKFKTVPSVTAATAIVNGN
                     FNQVADACEAIGNWISDNNYDVDGPMFNIYHVSPGNDSNPDNWVTEVCFPVKKK"
     gene            4509..5330
                     /locus_tag="PC494_003441"
     CDS             4509..5330
                     /locus_tag="PC494_003441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002572585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallohydrolase"
                     /protein_id="HDF3913895.1"
                     /translation="MKLKIVGSGGMSIIPSSFCKCKICEEARQKGGRYERLGPSLYID
                     DIKMLIDTPEDIAVACNRQKISEVKHISISHHDPDHVKGIRIVEKIGCDFITGENNPI
                     GFYALPEVIEDINRTNLDCLKYYGDVINCISINETSHVKINNFDIDLINNNPDRNITF
                     YVIKENEKKVIYACCNPKPFTHSDMYFDADILIISLVSDDGILNDGTKLKDTPFKDEI
                     FTLDEIVEIKNYYRIKKIIVTHIDEMWGKSYGYYSELEKKLDNIYFAYDGMEIIV"
     gene            complement(5640..6419)
                     /locus_tag="PC494_003442"
     CDS             complement(5640..6419)
                     /locus_tag="PC494_003442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="HDF3913896.1"
                     /translation="MSYKKIAIITGANSGFGKEFLKLLINEEEITEIWAVARNKARLN
                     QLVDEFGSKVKIFSKDLSKIEEVKEIGTFLSKENVCIKYLINNAGFAKFCSYNDLSID
                     ESINMIDLNISAVVALGLICIPYMQKGSHIMNISSQASFQPLPYQNIYSSTKAFIRNY
                     TRALNVELKSKGINAIAVCPGWMSTNLFKRGIVVAEKGTKNFPGIVSPDVVAKKALKD
                     AKKNKDISVYGINTKSSHLLAKLLPQKMMMKVWLMQQHIKE"
BASE COUNT         2473 a          896 c          837 g         2381 t
ORIGIN      
        1 tattatttat aatcttatct atatctttat gttaaatttt cttaacatgc attttttata
       61 tttaatatag taaaataatt aataactata tccatgattg gaggattttt atggttaaat
      121 ccaagaagaa aatatttgtt tttctaattt taattgcagt ttttattata tttgcatcat
      181 acataagaaa ttatactaat gatacaaaaa aagattctgt tagaggaact attccttttg
      241 aaaaaatgga atataagcgt cctaatatac agtcaatttg cgaaaacatt aacaaatgta
      301 acgacaaact tttaacagct aaaacagcta aggaacaatt aaatttattt aatgaagttg
      361 ataaaattta tcaggatttt tacagtacac ttactatagc aaaaattaga aataacatag
      421 attcatcaga cgaattttac tctaaggaat ataagtatct tatgagtaaa tcagtagatg
      481 ttgacatgtc atacaaagac tttcaagata gatttgtaac ttctaaattc tctaaagaat
      541 tagaaaaaga acttggaaat gatacattta attatctaaa gaacattgga aaacttaatt
      601 ctaaagaagt tgaaggtttg cttaaaaaag agcaagacct agttgtaaaa tatgaagact
      661 tattagctaa atctacagta tcaatagatg gtatagaggt agactttgaa gaagccttgt
      721 caagaccaaa tcttagccct gaagaatatg tgaaaattta ttcagattac ttaaaaaaat
      781 acaatcctat atttggtaac atattcttag aacttataca gacaagaact gaaatagcaa
      841 gtaagcaagg atttaagaat tatatagatt atgcctatat gaacctaaac aaagactatt
      901 ctcaagaaga agctaaaaaa tttagacaag atgtaaaaga ttacatagtt ccattatata
      961 gagagatttc atctaaacca tctgattctt ctatttatat taaagtatat aaaaatcgct
     1021 catttaggaa gtttgataaa gtacttgaag atatatctcc aaaactaaaa gagagcttcg
     1081 actatatgaa aaaatatgac ttgtacgatt attcttctgg aaaaaacaaa tcacctggag
     1141 gatatactac ttatataaat aaatataaag cacctttctt gtttaataca tgggacaatt
     1201 cttttttagg tgttactagt tttgctcatg agtttggtca tttttataat tactacaaca
     1261 gtattaactt aaataataag atgcaaccaa gtatagatgt atgtgaagtt cattcaacat
     1321 ctttagaaat tctattttat aaatattttg atgatttttt tggtaaacaa tctgaagcta
     1381 taaaaaaaga acacttatcg attgttttaa atactattat tgatgcttgt ctttatgatg
     1441 aatttcaaga aattatatac aagaatccat atatgagtct aaatgatatc aataaattgt
     1501 tttttgattt agaggaagaa tatggagttt ccaataatat acttagagaa aaaaatgctc
     1561 ctttttggat acttgtatct cataacttcc aagttccttt ttattacttg agttatggtc
     1621 ttgcatctga tgtatcactt cagatatggc aattatcaca agaagattac agaaaagctg
     1681 ttgatgtata tatggatttt ttaaatcaaa atactgatgc tggatttaaa gatgtggtag
     1741 aaaaggtaaa tttacaatta cctttccaaa atggaaattt agaggaaata agctctactt
     1801 tatatgatta ttttggtata gataatccac ttgaactaaa aaatgcttct taatttctaa
     1861 tactttatac tcactcttaa gatttagtat tagattgaaa taagtgatat tttttcacac
     1921 acaattaatg tttaataaaa ttatatggta aagtatcaga aatttttaag actcttgtct
     1981 ttataatttc tgatacttta tttattaata atattattat ttttttatat atataattaa
     2041 aaggattgtg gaaatcaata aaaatatccc tgtaaaaata gcactattca tatggaactt
     2101 aatagaactt gcatctgtta ccttattatt cttaatccag aacccacaaa ccatagttga
     2161 aagaaaaagt aaaacagtga taagacttga accaatagtt ataattttca tcttacatca
     2221 acatcctctc caataatatt ttctattaaa atatcaatga atttatctcg ctcatattta
     2281 ttctttatat ttataccact gtataactga aatgattctg tagataaagc agaaatctgt
     2341 attggtaaaa taatttgcag ggcaatgatt cttagactca tttcatcttt tttatttcca
     2401 aaaattttac gaagcatagg gacaatatca agttctgctt gcatatctcc attggttata
     2461 cattgattca atacaaaagg aagcactttt tcataatgta atccagtatc acacaatttt
     2521 tttaataaat tttttaaatc ttcaataggt cttagagtat atacactatc gtcatatagc
     2581 tctgctatta tatttgacat cacatctcct atggcagtac tcaacaaatt atcctttgtt
     2641 ttaaaatgat aatttattaa accaactcca acatttgcac gctcagcaat ttttctaact
     2701 gtaatctcct caatatcatc tacttcattt aaaagattca atgtaacttc aattatacgt
     2761 tctctagcat ctttatcatt acttttcata atagacctcc aaaacaatta acattttcag
     2821 ttctgaacat gttcagtata atattttttt catcatatgt caatataatt taattataat
     2881 tttagttgac tctaacatta tgatatggtt tatattaata ttaagctaaa agtaccttta
     2941 taaaggagac aaaaacatgt ttaagatagg cgatttttca aagctaagta aaattagtat
     3001 tcgtatgtta cgtcattatg atgaaatagg acttttaact ccttctcata cgaataaaac
     3061 taatggatat agatactata gtgcagacca actttctact acaaacagaa tccatgcact
     3121 aaaagatatg ggctttggct tgtattctat aaaagaaatt ttgacagaat ataacgataa
     3181 agaaagtctc ataaaatatc taaatatcca ccattctcaa gtaaaagaac aattagaaga
     3241 tacacagaaa aaactattaa aaatagaaac cactattaaa agaattggag gaaatgatat
     3301 tatgaaaaat tatgatgtaa ctataaagaa ttttgcacca aaatatatga tgacacttag
     3361 aagggttata ccaacttatc aagacgaagg aatgttatgg catcaagcat ttttagagac
     3421 aaaagaccag aatgttcaaa ttgaaccccc aaagtattct aaaacagttt tttatgatac
     3481 tggatataaa gaagattatg tagatgttga agtacaagtt gctgtatctg gaaagtataa
     3541 agatactgaa catgttaaat ttaagactgt tccaagtgtg actgctgcaa ctgcaattgt
     3601 taatggaaat ttcaatcaag ttgcagacgc ttgtgaggct attggtaatt ggatatcaga
     3661 taataactat gatgtggatg gtcctatgtt taatatttat catgtaagtc ctggcaacga
     3721 tagtaatcct gataattggg taacagaggt atgcttccca gttaaaaaga agtaattttt
     3781 atattaattg gataatattt taatttgtta gacaaattac ttttagtgtt atgtataaat
     3841 acctacaatt tgattaggat attatcttaa tttgttaaac aaattacttt tagtgttatg
     3901 tataaatatc tacaatttaa ttaggatatt atcttaattt gtcagataaa tcacttgtga
     3961 tgttatgttt aaatgactag aatttgattg ggatattatc ttaatttgtc agataaatta
     4021 cttataagat tacatacaac cctcatactc tagttaaata tttgaatcac taatataaat
     4081 tagtttttaa caaaacaaag agtaaagtac aaataattcc tttgtactct actcttttta
     4141 actttctttg tacaataata caatgataaa tataaaaaat tatatattcc attctataga
     4201 aatatgctca ccaataacat gtatgttgtt aatcaatata ttatatcaaa ttatatcaaa
     4261 attacataaa ccttatagga caatcatatc ttattacaag aaaaatgtct tatccatatt
     4321 gaataagtca ttcggttcat atacaaagtc aatttcattg agaaatattt aatatatgct
     4381 tataaaaatt tcatactatt ctttcatatt tacatgtgat ataatttatt aactcataat
     4441 tttgttaatc agttgtgatt gtagattatt tatataatct aatattttta gaaggtggtg
     4501 taataacttt gaaattaaaa attgttggta gtggcggtat gtcaattatt ccaagttcat
     4561 tttgcaaatg caaaatatgt gaagaagcca gacaaaaagg cggaagatat gaacgattag
     4621 gaccaagttt atatattgat gatataaaaa tgctgataga cacacctgaa gacattgcag
     4681 tagcttgtaa cagacaaaaa atatcggaag taaaacatat ttcaatttct caccatgacc
     4741 cagaccatgt taagggtatt agaattgtcg aaaaaatagg atgtgacttt atcacaggag
     4801 aaaataatcc aattggcttt tatgcgcttc ctgaagtaat tgaagatata aaccgaacga
     4861 atctcgattg tcttaaatat tatggtgatg ttataaattg catttctatt aatgaaactt
     4921 cgcatgtaaa gataaataat tttgatattg atttgattaa caataaccca gacaggaata
     4981 taaccttcta tgttatcaaa gagaatgaaa aaaaagtcat atatgcctgc tgtaatccca
     5041 agccatttac tcatagtgat atgtactttg atgctgatat tttaataata agtctagttt
     5101 ctgatgatgg tatattaaat gatggtacaa aacttaaaga cacaccattt aaagatgaaa
     5161 tatttacttt agatgagatt gttgaaatta aaaactatta tagaattaaa aaaattattg
     5221 ttacacatat tgacgaaatg tggggaaaat catatggtta ttacagtgaa ttagaaaaga
     5281 aacttgataa catttatttt gcatatgatg gtatggaaat tatagtctaa atcattaagt
     5341 aataagcata atgcaaaata agaaaacttc aatttaacag tatagtcaaa ctatgtgata
     5401 tcaacatatc gcagttttta caaaatatca tagtatttat ctttataaaa tttcaagtcc
     5461 tacatatttt aatacttcaa tatctaaata aagtaaaatc aaaaatatat tttatataca
     5521 ttatagacgg cttatcgtca ctagataagc cgttttgtca caattattat ttgctcaaca
     5581 aaacttctca taatatataa cagattgaat ctccaactga tacttaatta ccaaaactct
     5641 tattccttaa tatgttgttg cattaaccaa accttcatca tcattttttg tggcaatagt
     5701 tttgctaata aatgactgga ttttgtattt ataccataca cagaaatatc cttatttttc
     5761 tttgcatcct tcaatgcttt tttggcaaca acgtctggag acactatgcc tgggaaattt
     5821 tttgtccctt tttcagctac aactatacct ctcttaaata gatttgtact catccaacct
     5881 ggacatacag caattgcatt tatcccttta ctcttaagtt caacatttaa tgctcttgta
     5941 taatttctta taaacgcttt agttgaacta taaatatttt gatatggcaa tggctggaat
     6001 gatgcttgtg aagaaatatt catgatatgg cttccctttt gcatatatgg aatacatata
     6061 agtcccaatg ctacaacagc actaatattt aaatcaatca tattaataga ttcatctata
     6121 cttaaatcat tgtatgaaca gaattttgca aaaccagcat tgtttataag gtattttata
     6181 catacatttt ctttacttaa aaatgtacca atttctttta cttcttctat ttttgataaa
     6241 tcttttgaaa aaatttttac cttacttcca aattcatcta ctaattgatt taatctcgcc
     6301 ttgtttcttg caactgccca tatttctgtt atttcttctt catttattaa taactttaga
     6361 aactctttac caaaaccact attagcaccc gttataattg caatcttctt ataactcata
     6421 attattctcc tttaccataa gtttatacgc tcaaactgta aacttatttt ttacaaataa
     6481 aacaccctct attcagatgt tatattcata ttatttgaga tattatattt atatcatttt
     6541 caataattgt tatatagcat aaaaaatagt gttaatatta tagaatc
//
LOCUS       DAMKNB010000136         6549 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.142, whole genome shotgun sequence.
ACCESSION   DAMKNB010000136 DAMKNB010000000
VERSION     DAMKNB010000136.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6549)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6549)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6549
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.142"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            359..1633
                     /locus_tag="PC494_003443"
     CDS             359..1633
                     /locus_tag="PC494_003443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
                     /protein_id="HDF3913897.1"
                     /translation="MQFMDVSKYIEGANLKVKTKSGETVKRIYFNNSATPLVLKNVVD
                     NLNCEIPLLTYINAPGIISEKNTLKYENVRSTILKLIDGDEEKDSVIYVKNATEGINF
                     LAKFFKDENPDKFVITTAMEHMANYLPFKVNFPTKVVGITEKGELDLCQLENILKNYA
                     GNVSLVTVTGASNVTGITTPIYEIARIAHKYGAKILVDIVQVIQHKPFSMMPHECDEH
                     IDFVVFSAHKCYSPLNGGALVGPKKFFEKFNPVLYGSGSTKFVNDNKILYANVPQRFE
                     AGYPEYFGTLAMGKALNTLNKIGLNRISKYERELFLYAKEEMSKIPNIIIYGDKSNNV
                     IIPNISFNISNMYYKDVAKYLVDNFGIETGAGVVGADIYVQKLLGISPKEAYVRFMRE
                     NPVGLVRISLGMYNTFDEVDSFIHAIKTLAFK"
     gene            complement(1840..2157)
                     /gene="trxA"
                     /locus_tag="PC494_003444"
     CDS             complement(1840..2157)
                     /gene="trxA"
                     /locus_tag="PC494_003444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HDF3913898.1"
                     /translation="MVKIVNNNEFINEVENKDGLVVVDFFATWCGPCKMLSPIYEALG
                     NEMVEKANFLKVDIDQSIELAQKFEVSTVPTMLIFKDGKPVDRLIGFMPKENLKNKIE
                     SYM"
     gene            2424..3176
                     /locus_tag="PC494_003445"
     CDS             2424..3176
                     /locus_tag="PC494_003445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrmB family transcriptional regulator"
                     /protein_id="HDF3913899.1"
                     /translation="MDNIINELQNIGFTKYESQIYISLLKESPLTGYEISKLSGVPQS
                     KVYENITKLLNNNIIINVGTDPIKYIPINPNELLKNKKKEFDNSMDNLKNSLQILNKS
                     KSVEYVLNIKGDKNILKKAIEMIKNAKQEIIISCPYEEILELKKELLIAYKKNINIEI
                     LLLENKSLKGLDNIHIHGGNKTTLENKMLYKGIILIVDNDEILTGNLSEGSEAISIWT
                     KNSNILYIGVQYIKHEIYISEQIKGGYKNEQN"
     gene            3163..4044
                     /locus_tag="PC494_003446"
     CDS             3163..4044
                     /locus_tag="PC494_003446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhzF family phenazine biosynthesis protein"
                     /protein_id="HDF3913900.1"
                     /translation="MNKIKIKQVDAFTTIPFGGNPAGVVTDTSNISDEIKQNVAKEMN
                     LSETAFVSESNIADFKVQFFTPGLEVDLCGHATIGTFHALLEEGKLNTNKSIFYQETK
                     AGVLSVELKKINNENIFMMEQNTPEFENLDNCRKELAQMIGVHEDRLLEYPIIKVNTG
                     LWWLVFGLKSLDDLKNISPDLNKIKKFSGDNNIIGITPFCIETIDKKCDYHLRSIAPY
                     VGVTEDPVCGTGNACVSSYIVHHNILDKTSFIGEQGNFINRPGKVYVNITRENNNITS
                     VKIGGSAYTVLSGEIMY"
     gene            complement(4270..5625)
                     /locus_tag="PC494_003447"
     CDS             complement(4270..5625)
                     /locus_tag="PC494_003447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide MFS transporter"
                     /protein_id="HDF3913901.1"
                     /translation="MSSTVKKKGKFPMGFYICSTTFSFERAAYYASKYLIYIFLTTAI
                     VHGGLGIDKGQAAIMQANLVAFTYLAPIIGGYISDRWIGARYTIPIGMLIMGVGYYLG
                     SIATTVSMVNAMIILVSIGTAFFKGNVSAVNGQLFDSQEELDTAFSVQYSFVNIGSFI
                     GTIAVGILYLKTFAKNGVLGFSQCFFIAAVLCVIGAIWFIYGWRFLGNAGKRPFKEGV
                     VAEKIEEKDKSPLTSMDKKRIWAIILISFFSVIFWVFWYLTYLAVYDYGAAFVNMNVG
                     GFDVPLAWFDSLNSLVCIVLGPVLGALWFKLASRPQGDMSLFKKTGLGLIFLGLAFLM
                     LVGAEFSRGVGAPETAKASILWIIMFGILLSLGEMLFSPLGNSFVSKYAPKKLLGVLM
                     GVWTFATFIAGKGYGYIYAFTLKFDMIKVYTIIPVILFVAAILLFLSDKTLSRLVEDD
                     K"
BASE COUNT         2519 a          943 c          825 g         2262 t
ORIGIN      
        1 gttctaatca atttctttac tatttttaca actttattag tcatattcat aattatttct
       61 aattagtgtt taacatttta tgtaaaattt ataaaaaaat gtatataaat taaaataagt
      121 gactatacta aaaatatgat acggataaac aataagttca acctatctcc cccaaaatca
      181 agtgagctac agtttccccc aactgtagct cattttcgtg taatttaata aacatctcaa
      241 caagaattaa ttaacaaaac cccttataaa aacataacat atattaaaca agctcttgat
      301 taaaacttga gcttttttaa taaaaaacag aatagtttat tagataaggg gtttttttat
      361 gcaattcatg gatgtatcta aatacattga aggtgcaaac cttaaagtta aaactaaaag
      421 tggtgaaact gttaaaagaa tatattttaa caactctgcc actccattag ttttaaaaaa
      481 cgtagtggat aacttaaact gtgagattcc tttgcttact tatattaatg ctccaggaat
      541 aatctcagaa aaaaatactt taaaatatga aaatgtacgc tctactatcc tcaaacttat
      601 tgatggagac gaagaaaagg attctgttat ttatgtcaaa aatgctacag aaggaataaa
      661 cttcttagca aaatttttta aagatgaaaa tccagataaa tttgttatta ccacagcaat
      721 ggagcatatg gctaattacc tgccttttaa agttaatttt cctacaaaag ttgttggaat
      781 tacagaaaaa ggagaacttg atttatgtca attagagaat atacttaaaa attatgctgg
      841 taatgtatct ctcgttacag ttacaggagc tagtaatgtc acaggtataa ccactcctat
      901 atatgaaata gcaagaatag ctcataagta tggtgcaaag atattggtgg atattgtgca
      961 agtaattcag cataaacctt tttcaatgat gccacatgaa tgtgatgagc atatagattt
     1021 tgttgttttt agtgctcata aatgttattc tccactaaat ggaggagctc tggtaggacc
     1081 taaaaaattc tttgaaaaat ttaatcctgt actatatggc tcaggttcta ccaaatttgt
     1141 aaatgataac aaaatactat atgcaaacgt accccaacgt tttgaagcag gatacccaga
     1201 gtattttgga actcttgcaa tgggaaaagc actgaacact ttaaataaaa ttggtctaaa
     1261 cagaatttca aaatacgaaa gagaattatt tttatatgct aaagaagaaa tgagtaaaat
     1321 acctaatata ataatatatg gagataaatc aaataatgta attatcccaa atatatcttt
     1381 taatataagt aatatgtatt acaaagatgt agcaaaatat ttagttgata actttggaat
     1441 agaaactgga gctggagtag taggtgcaga tatttatgta caaaaattat taggtataag
     1501 tccaaaagaa gcatatgtca gatttatgag ggaaaatcct gtaggtcttg ttaggataag
     1561 cttaggaatg tacaatactt ttgatgaggt ggatagcttt atacatgcta ttaaaacttt
     1621 ggcttttaaa taagtttttt ctattctttt ttatcaataa atagagagta gttttgtttt
     1681 cacaaaaaag caaattatat caacagtcaa tttcattagc aattagacac tcatttgtaa
     1741 ctatacaaac tattttacac tatacaaaca aaaaactcat tacaatgagt ttttttgttt
     1801 atatatgaga tttattttaa ttacttcaat ttactttaat tacatatatg attcaatttt
     1861 gttttttaaa ttctccttag gcataaaacc tattaatcta tctacaggtt ttccatcctt
     1921 aaatattagc atagttggta ctgtagatac ttcaaatttc tgagctaatt ctatactttg
     1981 gtctatgtcc accttcaaga agtttgcttt ttcaaccatc tcatttccta aagcttcata
     2041 tattggtgat agcatcttac aaggtccaca ccaagtcgca aagaaatcta caactactaa
     2101 accatcttta ttttctactt catttataaa ttcattatta tttactattt ttaccataat
     2161 atacatctcc tttattatct tcttgatatt aatatactac gacctatata acagttcaat
     2221 taggcacttt tttgtaaccg cctattttta atagatttaa tattatgata aatagattta
     2281 taagattaaa tatttataag actaaatatt tctaatatat tttatttttt tcttaatata
     2341 gttgacattt tttcccttaa attataaaat caaattaata actacatagg tagttactaa
     2401 tcttttatca aaggagtttc tatatggata atattattaa tgaattacaa aatataggat
     2461 ttactaaata cgaatctcaa atatacatat cattattaaa ggaaagccct ttaacaggat
     2521 atgaaataag taaattatca ggtgtaccac aatcaaaagt ctatgaaaat ataacaaagc
     2581 tattaaacaa taatataatt atcaatgttg gaactgaccc tattaagtac ataccaataa
     2641 accctaatga attattaaaa aataagaaaa aagaatttga caattctatg gataatctaa
     2701 agaatagctt acagatatta aataaaagta aaagtgtaga atacgtatta aacataaaag
     2761 gagataaaaa tatattaaaa aaagcaatag aaatgataaa aaatgcaaaa caagaaatta
     2821 taatttcttg cccttatgaa gaaattcttg aattaaaaaa agaactccta attgcttaca
     2881 aaaaaaatat taatattgaa atactacttt tagaaaacaa aagtctgaaa ggtcttgata
     2941 atattcatat tcatggaggt aataaaacta cacttgaaaa taaaatgctt tacaaaggaa
     3001 ttattttgat tgtagataat gatgaaatat tgacaggaaa cttatcagaa ggcagtgagg
     3061 ccatttcaat ttggacaaaa aactctaaca ttttatatat tggagttcaa tacataaaac
     3121 atgaaattta tatttcagaa caaataaaag gaggttataa aaatgaacaa aattaagatt
     3181 aaacaagttg atgcttttac aactatacct tttggtggaa atcctgctgg tgtcgttact
     3241 gatacctcta acatttctga tgaaattaag cagaatgtgg ctaaagaaat gaatttatca
     3301 gaaactgcat ttgtttcaga gtcaaatatt gcagatttta aagtacaatt tttcacacca
     3361 ggtttagaag ttgatttatg tggtcatgca acaataggta ctttccatgc acttttggaa
     3421 gaagggaagc ttaatactaa taaaagtata ttttatcaag aaacaaaagc tggtgtatta
     3481 tctgtagagc ttaagaaaat aaataatgaa aatatattta tgatggaaca gaatacacct
     3541 gaatttgaaa atttagataa ttgcagaaaa gaacttgcac aaatgatagg tgtgcatgaa
     3601 gatagacttc ttgaatatcc tattataaag gtaaatactg gactttggtg gcttgtattt
     3661 ggtctaaaat ctttagatga tttaaaaaat atctctccag atttaaataa aatcaaaaaa
     3721 tttagtggtg ataataatat aattggtata actccatttt gtatagaaac tatagataaa
     3781 aagtgtgact accatttaag atctatagca ccatatgttg gagttacaga agaccctgta
     3841 tgtggaactg ggaacgcttg cgtatcatct tatatagtac atcacaatat tttagataaa
     3901 actagtttta ttggtgagca aggtaacttt ataaacagac ctggaaaggt atatgtaaat
     3961 ataactagag aaaacaataa cataacttct gtaaaaattg gaggaagtgc ttatactgtc
     4021 ttaagtggtg aaattatgta ttaatcccat acctaataaa aacaaataaa aatactagct
     4081 aactaaagct agtattttta tttgttattt ttatttaata atcatactct aacaaatatt
     4141 ataattatat atatcataat attgtattta gaagtaaaat tttattttta ttattaatta
     4201 gttataaatc aatctaatac aacataatta cagtagatta acctataaaa cataataatt
     4261 gcttactgat tatttatcgt cctcaacaag tctacttaat gtcttatcag ataagaataa
     4321 taatatcgct gcaacaaata gtattactgg aattatagta tatactttaa tcatatcaaa
     4381 tttaagagta aatgcatata tatatccata tcctttacca gctataaaag tagcaaatgt
     4441 ccatactccc ataagaacac ctagaagctt cttaggtgca tacttactta caaaagagtt
     4501 accaagtggt gagaataaca tttcaccaag acttaaaaga ataccaaaca tgattatcca
     4561 tagtatacta gctttagcag tttcaggagc tccaactcct cttgaaaatt ctgcaccaac
     4621 aagcattaag aatgcaagac ctaagaatat taatccaaga cctgtctttt taaataaact
     4681 catatctcct tgtggtctac tagcaagttt aaaccataat gctccaagaa ctggtcctaa
     4741 tactatacat acaagtgaat ttaatgagtc aaaccaagca agaggaacat caaatcctcc
     4801 aacattcatg tttacaaatg ctgcaccata atcataaact gcaagataag ttagatacca
     4861 gaatacccag aaaattacag agaagaatga tataagtata atagcccaaa ttctcttctt
     4921 atccatgctt gtaagaggag acttatcttt ttcttcaatt ttttcagcaa ctacaccttc
     4981 tttaaaaggt ctctttcctg cattcccaag gaatctccat ccatatatga accatattgc
     5041 acctattaca caaagtacag ctgctataaa gaaacattga gaaaatccaa gtacaccatt
     5101 ttttgcaaat gttttaaggt aaagaatacc aactgctata gtaccaataa aagaacctat
     5161 attaacaaaa gaatattgta ctgaaaatgc tgtatcaagt tcttcttgac tatcaaaaag
     5221 ctgtccattt accgcagata cgttaccttt aaagaatgca gtaccaattg aaactaagat
     5281 tatcattgca tttaccatag aaactgtagt tgcaatagaa ccaagatagt atcctacccc
     5341 catgataagc atacctatag gtatagtata tctagctcct atccatctat ctgatatata
     5401 ccccccaatt ataggtgcaa ggtatgtgaa tgcaacaagg ttggcttgca ttatagcagc
     5461 ttgtccttta tctattccaa gaccaccatg aactatagct gttgtaagga atatatatat
     5521 taagtacttt gaagcataat atgctgctct ttcaaatgag aaagttgttg agcagatata
     5581 aaatcccata ggaaatttac ccttcttttt tactgttgag ctcataattt taaatccttt
     5641 cttaattgta tttttatttt ttacgttttg tccaaattct ttcttttatg aaagatataa
     5701 tattattatt ttgtaaaaca atttgtaatt attattaaga taattgcgca tttatttgta
     5761 gagtacatat tctcatggaa taaaattaat acacttctta atcataaatt taaattatat
     5821 aaattcacta ttttcagata tagttataaa ttaatatatt ctcatctaat accatgaaaa
     5881 aaccttcgcc atatgcaatt cttatttttt acgtgatagt attttacaaa ctaaaatccc
     5941 ccttttgtag caacttatgt aattacattt tagtgctttt ttaaaggagt ctcgaataaa
     6001 gcaacatata ttttgttcaa ataatgtttt tatttatttt ttaaatttat atattacttc
     6061 acccaaccaa ttctcaactt aaataactaa actactatct attcacagat taggcttatt
     6121 tcttacacat tagtttataa taaacactgt gaatctaaac ataaaaactg ttattttaaa
     6181 gtaattaccc atatattcgc tttgatacta tttattgagg ctatactctt tatgtataat
     6241 atattattta taaaatacct caaaatatat tattcataaa atacctcaaa ctgaaaactt
     6301 tttcacgaat atttattttt cacctcccct tttttatttc accatgtaaa tcgtaccata
     6361 aatatgcact tatatgcaag aaaaaaatct attaatcgac agtaaataat tagaaaaatt
     6421 caaattatat ttatcaatta tattatataa aatatttcct atgaaaatat aaattaaatt
     6481 aatgttcaga atagttttta gatatgaaat cttgattttt ttattacttt acttatttgc
     6541 tcaaatata
//
LOCUS       DAMKNB010000137         6412 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.143, whole genome shotgun sequence.
ACCESSION   DAMKNB010000137 DAMKNB010000000
VERSION     DAMKNB010000137.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6412)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6412)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6412
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.143"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            complement(370..777)
                     /locus_tag="PC494_003448"
     CDS             complement(370..777)
                     /locus_tag="PC494_003448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3913902.1"
                     /translation="MSKVAKATFYLMIVTIISKILGMGRELVLSSIYGTGLYTESYLT
                     AMNIPNIIFAAIGTAIVTTFIPMYQDISSKQGEKQALKFLNNVLNIIVGICIVVAILG
                     VIFSKQLVSIFAIGFEGERFLLTVKFTKILIKK"
     gene            complement(1251..2135)
                     /locus_tag="PC494_003449"
     CDS             complement(1251..2135)
                     /locus_tag="PC494_003449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HDF3913903.1"
                     /translation="MDTKKENNYENYICVGSSNVSNAMKMYLKEIEEYKMLSAGEEVE
                     LAKEIINSSSVAKEKFINSNYRLVVSIAKRYKRDSIDMLDLIQAGNIGLIKAVEKYDY
                     KKGYKFSTYATWWIKQSITRYIDDCENTIRIPIHLHQRINFVKKKKQELLNVLLREPT
                     IDEIADACGLEVDKVLELLRRDKNVVSLDTPLKEDEDSSLVEFIPSDADFKDVVIHEV
                     EQHNLKEKIEELLTGLGEQEQQVLRMRFGIDDDDPKTLEQIGKVFGVTRERIRQIEAK
                     AIRKLRHPSKLKQLKHFY"
     gene            complement(2426..2902)
                     /locus_tag="PC494_003450"
     CDS             complement(2426..2902)
                     /locus_tag="PC494_003450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction enzyme HsdR N-terminal
                     domain-containing protein"
                     /protein_id="HDF3913904.1"
                     /translation="MSKELVKDRVIKYLIEDLLVPQDMIDTNVELAEFEEGAEGILDI
                     VVNVKDEEDYYAPVMIVQCLDEDVELEGEVLQKQIEFLEEVDNITMSGRLVLTNGDAM
                     MYADWRGEEYDTEAALPTYDIMVKEFHEMEQQVKDLEEHHHHDENCGCGCNHHHEN"
     gene            3168..4343
                     /locus_tag="PC494_003451"
     CDS             3168..4343
                     /locus_tag="PC494_003451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1002 domain-containing protein"
                     /protein_id="HDF3913905.1"
                     /translation="MKFKKQISSIVVSTMLVLGSMNLSYADGTNVVTLGANLSESQKQ
                     QMLNYFGVKKDQVLVLDVTNAEERQYLQGVATEGQLGKVTISCSYVEPTKKGNGINVK
                     TANLTWVTSSMIASTLTTAGLEDANVIAAAPYPVSGTGALTGIMKAFEDASGKKLDET
                     KKEIASEELVVTGDLGDDIGQEKATGVMNDIKTEIVKNGTKDTNQIANTINNVVNNYN
                     ITITPEQKEQIKGVMKKIADQNYDYNSMKNTLDNVSDNVNEQLKKLGESVKGSGILDT
                     IGGWFSGIGDWFSGLFSGGDKKDLGILNNTNDESLGSDAVINSTEGVQINPQNNTNSN
                     NDSDTNSSKNDTSSNNENNDSSQTNENNTTNNSENQSNNNDSVGFFEKIKNWLSGLF"
     gene            complement(4424..5227)
                     /gene="proC"
                     /locus_tag="PC494_003452"
     CDS             complement(4424..5227)
                     /gene="proC"
                     /locus_tag="PC494_003452"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HDF3913906.1"
                     /translation="MKKIGFIGAGNMASAMIGGIVNSKLVEPNMVIASAYSQGTLDRI
                     DANFGINTTKDSKEVTRTSDIVIVAVKPDIYDDILEEIKDFIDDNKIIVTIAAGKSIK
                     DIESIIGEDKKIVRTMPNTPALVNEAMSSLSINKNINKEDLEAVTEVFNSFGNTEVVP
                     EYLIEAVIGASGSAPAYVFLFIEAIADAAVIAGMPRPQAYKFASQAVMGSAKMVLETG
                     KHPGELKDMVCSPGGTTIEAVKVLEEEGFRASVIKAICACIEKSKKMSE"
     gene            complement(5267..5851)
                     /locus_tag="PC494_003453"
     CDS             complement(5267..5851)
                     /locus_tag="PC494_003453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF3913907.1"
                     /translation="MNKDIGAKIKQLRTQKQMTLKDMSEKTNLSIGFLSQLERGLTSV
                     ATDSLGKIASVLDVELTYFFMKPKEHKRAVLRSYEKEVFDVENSTFIHYHLSSSLKEK
                     TMLPRLIEILPSKSSEEICCYVHEGEEFVYVLEGTLTVFLGDEQIEMYPGDTIHYNSE
                     KNNHNWVNYTNKVVKILVVSIPNPFEKSDAVKEA"
BASE COUNT         2114 a         1094 c          722 g         2482 t
ORIGIN      
        1 aagcacagac tatatcttat ccttcagcat tatccgttaa ggtctaccca cttccactac
       61 caatagcttg tagtgtactt ccctcaagag gaatagtcgt tgaagtttct cctattcgga
      121 gtttacctgc tgattgccca ttttaaagta cttaggattt aaccttatac catctaacca
      181 attttttcta ctttcgtaac tttcacactt aggtttattt catccttatg ttttagtttg
      241 attagcttta ggggtttcca gcaattcaag tagtattgga taggttctat cctatctcta
      301 catataggtt tccctatatg ctgactattt tagctactaa ctcatgacta aagtcacgag
      361 tgtgcgtagc tattttttaa tcaatatttt agtaaatttt acggtaagta aaaacctctc
      421 tccttcaaat cctatagcaa atatacttac aagttgcttt gagaaaataa ctcctaatat
      481 agctacaact atgcatatac caactattat atttaaaaca ttgtttaaaa actttagtgc
      541 ttgcttttca ccttgtttac tacttatatc ttgatacatt ggaataaaag tagtaactat
      601 agcagtacct attgctgcaa atataatatt tggtatattc atagctgtta aataactctc
      661 tgtatataag cctgtaccat aaattgatga taatactaat tctctaccca ttccaagaat
      721 cttagagatt atagtaacta tcatcaaata aaaagttgct ttagctacct tgctcatttt
      781 atcactccac ttctaacata cctcttttta atcaagtaaa atttagctca ttagatataa
      841 ttctatcaac taatttgcct tgcttagccc tatcaaaata taattaacac ctatttctta
      901 atatatcaca aactacatta ttcttcatat ttttttattt ctccaataag ttttacattt
      961 ttcctatata aattgtatag cttcaattat attcaaagaa atggagttgc tacccgataa
     1021 ctttaaaagt aaaaaacaga ttttattatc tttttaaact atattctaac atattttgtc
     1081 catattgaga aattttacta aactattatg tactttatta aataaataaa ataacagcac
     1141 acctataaaa tacaagtgtg ctgttcataa acagatttta taaaaaaata attcctaagt
     1201 agagattaac atgctttctc atactctcat atataatgtg tctaaaaata ttaataaaaa
     1261 tgctttaatt gttttaactt acttggatgt cttaattttc ttattgcttt agcttctatc
     1321 tgtcttattc gttctctggt aactccaaat acctttccaa tctgttctag tgttttaggg
     1381 tcatcatcat caattccaaa tctcattctt aaaacttgct gttcttgctc tccaagacct
     1441 gtaagtagtt cttctatctt ttcttttaaa ttatgctgtt caacttcgtg tattacaaca
     1501 tctttaaaat cagcatctga tggtataaat tcaactaaac tactatcctc atcttctttt
     1561 aatggagtat ccaaagatac aacattttta tctcttctta ataattccaa cactttgtca
     1621 acttctaagc cacatgcatc tgcaatctca tctatagttg gctctcttaa taatacattt
     1681 aaaagttctt gtttcttttt ctttacaaaa tttattctct gatgaagatg tataggtatc
     1741 ctaatagtat tttcgcaatc gtcgatatat cttgttatac tttgttttat ccaccaagtt
     1801 gcataagtgc taaatttgta tcctttttta taatcgtact tttctacagc ttttataagt
     1861 cctatatttc ctgcttgaat taaatccaac atatcaatac tatctctttt atatctcttt
     1921 gctatgctca ctaccaacct ataatttgaa tttataaatt tttcttttgc tactgaagat
     1981 gagttgatta tttccttagc cagctctacc tcttctcctg ctgacaacat tttgtattcc
     2041 tctatttcct ttaaatacat tttcatcgca ttcgatacat ttgatgaacc cacacaaata
     2101 taattttcat aattattttc ttttttagta tccataatca aaccccttct attcatagaa
     2161 tttgctaaaa caaaaataaa taatttaaac ctacataatc tacaattaca taatatccca
     2221 ttctttaaat gaattgtttt gtatattatg tatacaaatt tataaaaact atacctataa
     2281 tattattcta cttctaacag caatatcctc cttatatata taatttattt tattatatgt
     2341 tgttatattc ttagtttttt gaatgatata tgtctaaaaa aagactgttt actaaacagt
     2401 ctttttttat atatatgctc aatatttaat tttcatgatg atgattacat ccacatccac
     2461 aattttcatc atggtgatga tgttcttcta aatcttttac ctgttgttcc atttcatgaa
     2521 actcttttac cattatatca taagttggaa gagctgcctc agtatcgtat tcttcccctc
     2581 tccaatcagc gtacatcata gcatctccat tagttaaaac caatctacct gacatagtta
     2641 tattatccac ttcttctaaa aattctattt gtttttgtaa aacttctcct tctaactcca
     2701 catcttcatc taaacattgc actatcatta caggtgcata ataatcttct tcatctttaa
     2761 catttacaac aatatctaaa attccttctg caccttcttc aaattctgcc aactcaacat
     2821 ttgtatcaat catatcttga ggtactaata aatcttctat taaatatttt attactctat
     2881 cttttactaa ttcttttgac atttattttt ctccttccga ttctataaca ttatcataat
     2941 catttctata ttatagtata ctacattaat tgttttttca atctcttaca aaaattattt
     3001 tttattatct tccttatatt ccctttttta ttacaaagtt gtaatcgcat tgatttaaaa
     3061 aatagtttat atttagtata atagaaatgt agcacatatt tttattcaat atattaataa
     3121 aaaaatatat tgaaaatgta atgtatgtta aatctaggag gaatattatg aagtttaaaa
     3181 aacaaattag ttctattgtt gtgtctacta tgcttgtact tgggagtatg aacctttctt
     3241 atgcagacgg tacaaatgta gttacacttg gagctaactt atcagagtct caaaagcagc
     3301 aaatgcttaa ttactttgga gtaaaaaaag accaagtctt agttttagat gtaacaaatg
     3361 cagaagaaag acagtattta caaggtgttg caacagaggg tcaacttgga aaagttacta
     3421 tctcttgctc atacgttgaa cctactaaaa aaggaaatgg aattaatgtt aaaacagcaa
     3481 acttaacttg ggtaactagt tcaatgattg cttcaaccct tacaacagct ggtcttgaag
     3541 atgcaaatgt tattgctgct gctccatatc ctgtaagtgg tactggagca ttgacaggaa
     3601 tcatgaaagc atttgaggat gcttcaggaa agaaacttga tgaaactaag aaagaaattg
     3661 cttctgaaga attggtagtt acaggtgact taggagatga tatagggcaa gaaaaagcaa
     3721 caggtgtaat gaatgatata aaaacagaaa ttgtaaagaa tggtacaaaa gataccaatc
     3781 aaatagcaaa tacaataaat aatgttgtaa ataattacaa tattactatt acaccagaac
     3841 aaaaagaaca aattaaaggt gtaatgaaaa aaatagctga ccaaaattac gattacaata
     3901 gcatgaaaaa tacactagat aatgtatcag ataatgtaaa tgaacaatta aagaaattag
     3961 gtgaaagtgt taagggttct ggtatactag atactattgg tggatggttt agtggaatag
     4021 gagactggtt ctctggttta ttctcaggcg gagataaaaa agatttggga atcttaaata
     4081 atactaatga tgagtctctt ggctctgatg ctgtaataaa ttctacagaa ggtgttcaaa
     4141 taaatccaca aaataatact aattctaaca atgatagtga tacaaatagc tcaaaaaatg
     4201 atacttcaag taataatgaa aataacgata gttctcaaac aaatgaaaac aacacaacaa
     4261 ataattcaga aaatcaatca aataataatg actcagttgg tttctttgaa aaaataaaaa
     4321 attggctttc aggcttattt tagaaattaa acaaataaaa agaattgcct aaaatggaaa
     4381 ttttctataa aaggcaattc tctttattta caataaattt ttattactca ctcatttttt
     4441 tagatttttc tatacatgca catattgctt ttatcacaga agctctaaaa ccttcttctt
     4501 caagtacttt aactgcttct atagtagttc caccaggtga acataccata tcttttaatt
     4561 caccaggatg ttttcctgtc tcaagtacca tttttgcaga acccataaca gcctgtgatg
     4621 caaacttata tgcttgtggt cttggcattc ctgcaattac tgctgcatct gctatagctt
     4681 ctataaataa aaatacatat gctggtgcag aaccacttgc accaattaca gcttctataa
     4741 gatactctgg tactacctca gtatttccaa aagaattaaa tacttctgta actgcttcta
     4801 agtcttcttt gtttatattt ttatttatcg aaagagaaga catggcttca tttacaagag
     4861 ctggagtatt tggcatagtt ctaactattt ttttatcttc tcctataata gactctatat
     4921 cttttataga ttttcctgct gctattgtaa ctataatttt attgtcatct ataaagtctt
     4981 ttatctcttc caaaatatca tcatatatat ctggtttaac agctacaatt actatatcag
     5041 aggttctagt tacttccttc gagtcttttg tagtatttat tccaaaattt gcatctattc
     5101 tatcgagagt tccttgacta tatgctgatg ctataaccat attaggttca actaattttg
     5161 aatttactat tccccctatc atagcgcttg ccatatttcc tgcacctatg aatccaattt
     5221 ttttcacttt agtacctcct tattgactaa tagtaatcgt taaaatttaa gcttctttaa
     5281 ctgcatcaga tttttcaaat ggatttggta tacttactac caaaattttc actaccttat
     5341 tagtatagtt gacccaatta tgattgttct tttcactatt atagtgtatt gtgtctcctg
     5401 gatacatttc tatttgttca tctcccaaaa acactgtaag agtaccctct aatacataca
     5461 caaattcctc accttcatgt acgtaacaac aaatttcctc actactctta cttggaagaa
     5521 tttcaattaa tcttggtagc attgtttttt cctttaaact agatgataaa tgataatgta
     5581 taaatgttga gttttctaca tcaaatactt ctttttcata acttcttaat acagctcttt
     5641 tatgctcttt tggcttcata aaaaagtaag ttaattctac atctagtaca cttgctattt
     5701 ttcctaagga atctgttgcc acacttgtta atcctctttc aagttgtgat aaaaaaccaa
     5761 ttgacaagtt tgttttttca ctcatatcct tcagcgtcat ttgcttttga gttctgagtt
     5821 gctttatttt tgctcctatg tccttattca aaaccatcac ccctaaataa ttttaatttt
     5881 ttcataatat aaatacaaaa atataaatat aggtactgaa cccatcttta tttcatttaa
     5941 aaaaattttt ataagtatta ctataattta tcaatctttt tttgtctaca tttttacgat
     6001 tatttacgat ttatttttca catatgtata tttaatcttg ccaactaaag atacattttt
     6061 tataagcatt tactctttat ataataaaac ttaagttgtt catgtagtct tcttctggtt
     6121 taattattaa aatttcaaat tatattatta tttctacaca ttattacatc ctttagtaca
     6181 attataacat aattttacaa tttaatgata tctattcaat gtcttttttt actctacaac
     6241 atattttatt ttagagttta atactatata tattttttat atacagcctt gtcatttttt
     6301 agattgtcaa gagttattga agtattttat gtagatttag attttatttc ctaatttctc
     6361 atttaacaag aattgcttat gataaaaaat aatatcatct caataagatt ct
//
LOCUS       DAMKNB010000138         6386 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.144, whole genome shotgun sequence.
ACCESSION   DAMKNB010000138 DAMKNB010000000
VERSION     DAMKNB010000138.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6386)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6386)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6386
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.144"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            302..1246
                     /locus_tag="PC494_003454"
     CDS             302..1246
                     /locus_tag="PC494_003454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP phosphoribosyltransferase regulatory
                     subunit"
                     /protein_id="HDF3913908.1"
                     /translation="MKFLRIEDEVIYSKKRYKLKREIDKLFLDEEYFQIEPQLFEEYD
                     EFTTINNKIPEESMVKVVNGKVMVLRADITTSIIKSLVPRWEDGLKLKLFYNSSIYKN
                     KNTVGIKEIRQIGCEYLGEASVEADREVVKLALKILEKYNNNFILEVGSSKYIHGLLE
                     ELNLNKNCENQIKNLLYTKNTHELKVYIEELKIKREVKELLSNILSLQGNLYNVIEKS
                     NKFYCNNKMKQALEELKQVNNLIEECNFLDKARFDLSMITMLDYYEGIMFRGYYPNSY
                     KEILSGGRYDSLTKEYGKEIPAIGFTLSVDELMKYVYK"
     gene            1268..1894
                     /locus_tag="PC494_003455"
     CDS             1268..1894
                     /locus_tag="PC494_003455"
                     /EC_number="2.4.2.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP phosphoribosyltransferase"
                     /protein_id="HDF3913909.1"
                     /translation="MDYLTIALAKGRIEGESFKKFKKMGLGDSIDTDTRKLIFKDEEN
                     KIIYIHVKPSDVVTYVEKGVADLGIAGKDTILENETDVYEIYDLGFGKCKFAVAGLKG
                     DSIYREDEYLKVATKYPNIAKKYFKEKGQKIEIIKLNGSVELAPIVGLSDVIVDIVET
                     GNTLKANGLEILEDICNISARIISNRASYRFKYEQIQNIIRLFEELDN"
     gene            1928..2977
                     /gene="hisC"
                     /locus_tag="PC494_003456"
     CDS             1928..2977
                     /gene="hisC"
                     /locus_tag="PC494_003456"
                     /EC_number="2.6.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphate transaminase"
                     /protein_id="HDF3913910.1"
                     /translation="MREKESIRELKGYEPNHVNCKVKLDANEGSKRLFKYLIKEISDS
                     DIDLNLYPEDSYSDLKESIIDYINISGVNKKNLLVGNGSSEIIDLIIHTFVDKDEVIL
                     SFSPSFSMYSIYSQINGSKFIGVESDENLVINIDNVIEKVKENNPKIVIVCNPNNPTG
                     TILKREEIIKLLDSTNSLVVLDEAYMDFGEESMLSDVFKYDNLIVLRTLSKAFGLAGI
                     RTGYMLSNSSLINSVEKVRPPYNLNSLSDFIATRALRNKDVVKAYIKEVKEEREVLYK
                     EMIGMGIKAYKSQANFILFYSEIENLSQKLIDRGVLIRKFGGKLENYYRVTIGDKEEN
                     SMFVGAIRDILKKEK"
     gene            2980..3558
                     /gene="hisB"
                     /locus_tag="PC494_003457"
     CDS             2980..3558
                     /gene="hisB"
                     /locus_tag="PC494_003457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="imidazoleglycerol-phosphate dehydratase HisB"
                     /protein_id="HDF3913911.1"
                     /translation="MRIWKVERNTLETQILVELNIDGSGKAEIDTGIGFLDHMLTLMS
                     FHGKFDLKVICKGDTYVDDHHSVEDIGIAIGEAFKNALGDKKGIRRYSNIYIPMDESL
                     SMVAIDISNRPYLVFNAKFDTQMIGSMSTQCFKEFFRAFVNESRVTLHINLLYGENDH
                     HKIESIFKAFARALKEGSEIVSNEIASSKGVL"
     gene            3560..4165
                     /gene="hisH"
                     /locus_tag="PC494_003458"
     CDS             3560..4165
                     /gene="hisH"
                     /locus_tag="PC494_003458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="imidazole glycerol phosphate synthase subunit
                     HisH"
                     /protein_id="HDF3913912.1"
                     /translation="MNIIVDYGLGNIDSVSRGFRKAGIETKISSDIDEIKQADSLILP
                     GVGAFRDSISALDKLGLIPIIKEHVSKGKFMIGICLGMQLLYEKSYEYGEYEGLGLIK
                     GSIDKLDISLKVPHMGWNNLKFNKANDDILKYINEDDYVYFVHSYYANSSNEELIAFS
                     EYEKKIPAIVRKGNVYGIQFHPEKSGEVGLNILRAYGEMIK"
     gene            4162..4884
                     /gene="hisA"
                     /locus_tag="PC494_003459"
     CDS             4162..4884
                     /gene="hisA"
                     /locus_tag="PC494_003459"
                     /EC_number="5.3.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-(5-phosphoribosyl)-5-[(5-
                     phosphoribosylamino)methylideneamino]imidazole-4-
                     carboxamide isomerase"
                     /protein_id="HDF3913913.1"
                     /translation="MIIFPAIDIKDNKCVRLTQGEFDKVNVYYDNPLEVAYKWKNEGA
                     EYIHIVDLNGARSEFGVNTKIIEDIANNIDIPIQVGGGVRDKEKVKSLINAGVTRVIL
                     GSIAIENLNLVEELVNEYKEKIVVSIDAKDGKVAVRGWEVVSNVDSLTLCKQLEKIGV
                     QTIVYTDISKDGMLQGPNFDIYERIAKETSLNVIASGGVTSIEDVKRLKAMNLYGAII
                     GKALYDKKIDFKEAQQLCLLGE"
     gene            4866..5624
                     /gene="hisF"
                     /locus_tag="PC494_003460"
     CDS             4866..5624
                     /gene="hisF"
                     /locus_tag="PC494_003460"
                     /EC_number="4.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000880088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="imidazole glycerol phosphate synthase subunit
                     HisF"
                     /protein_id="HDF3913914.1"
                     /translation="MLTRRIIPCLDVRNGRVVKGKKFKDIVDVDSPEVLGKFYSDCGA
                     DELVFYDITASNEERKTSLEFVTKVAENINIPFCVGGGVNKLEDFTDILRKGADKVSI
                     NSSAVKNPELIREASLKFGAQCVVLSIDAKKNEEGSWSVYVKGGREKTNLDAIEWAVK
                     GVELGAGEIVVNSMDEDGMKNGYDIELLSKITSLVNVPVIASGGAGKKEDFYEAVNKS
                     NVDGILAASVFHFGEIKINDLKKYLKDMGVEVRL"
     gene            5652..6320
                     /locus_tag="PC494_003461"
     CDS             5652..6320
                     /locus_tag="PC494_003461"
                     /EC_number="3.5.4.19"
                     /EC_number="3.6.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional phosphoribosyl-AMP
                     cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE"
                     /protein_id="HDF3913915.1"
                     /translation="MDNKCNNVYSDEVEKFIRSIKFDDKGLVPVVVQEVVSKDVLMLA
                     YMNKDAIKKTLKDKVACYFSRSRQELWVKGETSGNTQKVVKMSYDCDVDTILLFVEQT
                     GVACHTGNYSCFYRDLFDDSSKMELEVQTNILKELYDLINERKNNPVEGSYTNYLFEK
                     GIDKILKKVGEESSEVIIASKNTDKSELIYEISDLVYHTLVLMIEKGVEIDEIKKELL
                     KRRK"
BASE COUNT         2610 a          540 c         1260 g         1976 t
ORIGIN      
        1 caaaaaactg taaatttaga atattaataa aaattatttg ggaggaaatt atcatggtga
       61 gattaaatat agtaaaatta aatacaaaat taaatcatca ccatcatcat agattaaagg
      121 gattgtaata tgaaattaat tcatagacac aagccctgtt tttagtgtaa ttggtcttgt
      181 atctatgatg ggaagtaatt ttaagagaaa attatagcca tataggtata aagcctatgt
      241 ggctttttta ttgttttaaa tttgcaaata taagagtaaa tttaatgaag agggtgagaa
      301 tgtgaaattt ttgaggattg aagatgaggt tatttattct aaaaaaagat ataaattaaa
      361 aagggaaata gataaacttt ttttggatga agaatatttt caaatagaac cacaattatt
      421 tgaagaatat gatgaattta caactataaa taataaaatt ccagaagaat ctatggtaaa
      481 ggttgtaaat ggaaaagtaa tggtacttag agctgatata actacaagta taataaaaag
      541 ccttgtacca agatgggaag atggtttaaa gcttaagctt ttttataatt catcaatata
      601 taaaaataaa aatacagttg gaataaaaga gataagacaa ataggttgtg agtatctagg
      661 agaagcctct gtagaagcag atagagaagt agtgaaatta gctcttaaga tacttgaaaa
      721 atacaataat aattttattc tagaggttgg gagtagcaag tatattcatg gtttgttaga
      781 agaattaaat ttaaataaga attgtgaaaa tcaaattaaa aatttactat atacgaagaa
      841 cactcatgaa ctaaaagtat atattgaaga attaaaaatt aagcgtgaag taaaagagtt
      901 attatcaaat attttaagtt tacaagggaa tttatataat gttattgaaa aatcaaacaa
      961 gttctattgt aataataaga tgaagcaagc tcttgaagaa ttaaagcaag taaataattt
     1021 gattgaggaa tgtaattttt tagataaggc tagatttgat ttatcaatga ttactatgct
     1081 tgactattat gaaggaatta tgtttagagg atactaccca aactcatata aagaaattct
     1141 tagtggtgga agatatgatt ctttaactaa agagtatgga aaagaaattc cagccattgg
     1201 atttacacta agtgttgatg agttaatgaa gtatgtatat aagtaaagtt tagaaggagg
     1261 gattgctttg gattatttga ctatagcact agcaaaagga cgaattgaag gggaatcatt
     1321 taaaaaattt aaaaaaatgg gtctaggaga cagtatagac acagatacga gaaaactaat
     1381 ttttaaagat gaagaaaata aaattatata tatacatgta aagccatcag atgtagttac
     1441 atatgttgaa aaaggagtcg ctgacctcgg tatagcaggt aaagatacta ttttagagaa
     1501 tgagacagat gtatatgaaa tatatgattt aggttttgga aaatgtaaat ttgctgtagc
     1561 aggattaaag ggagatagca tatatagaga agatgaatat ttaaaagtgg caacaaagta
     1621 tcccaatata gcaaaaaagt attttaaaga gaaaggtcaa aaaattgaaa taataaaatt
     1681 aaatggttct gtagaactag ctccaatagt agggttgtca gatgtaattg tagatatagt
     1741 tgagactggc aatacactta aagcaaatgg tcttgaaata ttagaagaca tatgtaatat
     1801 aagtgctaga attatatcaa atagagctag ctatagattt aaatatgaac aaattcagaa
     1861 tataattcgt ttatttgaag aacttgataa ttaaaatata attgagcttt ataaggaggg
     1921 atttaagttg agagaaaaag aaagcataag agagttaaag ggatatgaac caaatcacgt
     1981 aaactgtaaa gtaaaacttg atgcaaatga aggaagtaag aggttgttta aataccttat
     2041 taaagaaatt tcagatagtg atatagattt aaatttatat cctgaagatt cttatagtga
     2101 tttgaaagaa tctataatag attacataaa tatttctgga gtaaataaga aaaatcttct
     2161 agtaggaaac ggttcaagtg aaataattga tttaataata catacttttg tagataaaga
     2221 tgaagtaata ttgagtttct ctccaagttt tagtatgtat tctatatata gtcagataaa
     2281 tgggtctaaa tttataggtg ttgaaagtga tgaaaattta gttataaata tagataatgt
     2341 gattgaaaaa gtaaaggaga ataatcctaa aatagtaatt gtatgtaatc ctaataatcc
     2401 aactggaaca atattaaaga gggaagagat aataaagctt ttagattcaa ctaatagtct
     2461 agtggtttta gatgaagcat atatggattt tggagaagaa agcatgttaa gtgatgtttt
     2521 taagtatgat aatctaatag ttcttagaac tttatcaaag gcatttggat tggctggaat
     2581 aagaacagga tatatgttat ctaatagtag tttaataaat tctgttgaga aagtaagacc
     2641 tccatataat ttaaattcat tatcagactt tattgctaca agagcactta gaaataaaga
     2701 tgtggtaaag gcttatataa aggaagtaaa agaggaaaga gaagttttat ataaagaaat
     2761 gattggtatg ggaattaaag catataaatc acaagcaaat tttatattat tttattctga
     2821 aatcgaaaat ttatcacaaa aacttattga tagaggtgtt ttaataagaa aatttggtgg
     2881 aaagttagaa aattattaca gagttacaat tggtgataaa gaagaaaatt ctatgtttgt
     2941 tggagctata agagatattt tgaaaaagga gaaataggta tgagaatttg gaaggtagaa
     3001 agaaatactc ttgaaacaca gattttagta gaattaaata ttgatggttc tggtaaagct
     3061 gaaatagata ctggaatagg atttttagac catatgctta ccttaatgtc atttcatggc
     3121 aagttcgatt taaaagtgat ttgtaagggt gatacatatg tagatgacca ccatagtgta
     3181 gaagatatag gtatagctat aggtgaagca tttaaaaatg ctctaggtga caaaaaagga
     3241 atacgaagat attctaatat ctatatacct atggatgaat ctctatcaat ggtagcaata
     3301 gatataagca atagacctta tcttgtattt aatgctaaat ttgataccca aatgattggt
     3361 agtatgagta ctcaatgctt taaagaattt tttagagctt ttgtaaatga atcgagagta
     3421 acattacata tcaatctctt atatggggaa aatgaccatc ataagataga aagtattttt
     3481 aaagcatttg caagagcttt aaaagagggt agtgaaatag tttctaatga gatagcatct
     3541 tcaaaggggg ttttgtagaa tgaatataat agtagactat ggtcttggaa atatagattc
     3601 tgtgtctagg ggttttagaa aagctggaat agaaactaaa atttctagtg atatagatga
     3661 aataaaacag gcagattcac ttatacttcc aggtgttgga gcttttagag attctataag
     3721 tgccttagat aaactaggat tgataccaat aataaaggag catgtttcta agggtaaatt
     3781 tatgataggt atatgtctag gaatgcaatt actttatgaa aaaagttatg agtatggaga
     3841 atatgaagga ttaggactta taaaaggaag tattgataaa ctggatataa gtttaaaagt
     3901 gccacatatg ggatggaata atctaaaatt taataaggca aatgatgata tacttaaata
     3961 tataaatgaa gatgattatg tatacttcgt tcactcatat tatgcaaatt catcaaatga
     4021 agaactaatt gcattttcag aatatgaaaa gaaaatccct gctattgtta gaaaaggcaa
     4081 tgtatatggt atacaatttc atcctgaaaa aagtggagaa gtagggttaa atatattaag
     4141 agcatatggg gagatgataa aatgataata tttccagcaa tagatataaa agataataag
     4201 tgtgtaagac tcacacaagg agaatttgac aaagtaaatg tatattatga taatccatta
     4261 gaagtagcat ataaatggaa aaatgaagga gcagaatata tacatatagt agatttaaat
     4321 ggtgctagaa gtgaatttgg tgtaaataca aaaataattg aggacatagc aaacaatata
     4381 gatataccta ttcaagttgg cggtggagtt agggataagg aaaaagtcaa aagtttaata
     4441 aatgctggtg ttactagagt aatattaggc agtatagcga ttgaaaattt gaatttagtt
     4501 gaagaattgg tcaatgaata taaagagaaa attgtagttt ctatagatgc taaagatgga
     4561 aaagtagcag ttaggggatg ggaagttgta agcaatgtag actcattaac attatgtaaa
     4621 caacttgaaa agataggtgt acaaactatt gtttatacag atatatcaaa agatgggatg
     4681 ttgcaaggtc caaattttga catatatgaa agaatagcaa aggaaacatc actaaatgtt
     4741 attgcttctg gaggcgtaac ttctatagaa gacgtaaaaa gactaaaagc tatgaactta
     4801 tatggtgcaa taataggtaa agcgctttat gataaaaaga tagactttaa ggaggcacaa
     4861 caattatgct tactaggaga ataatacctt gtctagatgt gagaaatgga agagttgtaa
     4921 aggggaaaaa atttaaagat atagtagatg ttgatagtcc agaagtactt ggaaaatttt
     4981 atagtgattg tggtgcagat gaacttgtat tctatgatat aactgcatca aatgaagaga
     5041 gaaagacatc tttagaattt gtgacaaaag ttgcagaaaa tataaatata ccattttgtg
     5101 ttggtggagg agtaaataaa ttagaagatt tcactgatat tttaagaaaa ggtgctgata
     5161 aagtttctat aaattcatca gcagtcaaaa atcctgaatt aataagggaa gcttcattaa
     5221 aatttggagc acaatgtgtt gttttatcga tagatgcaaa gaaaaatgaa gagggttcat
     5281 ggagcgtata cgtaaaaggt ggaagagaaa aaactaatct ggatgcaatt gaatgggctg
     5341 ttaaaggtgt agaacttgga gcaggagaaa tcgttgtaaa tagtatggat gaagatggaa
     5401 tgaaaaatgg atatgatata gaattattat caaagataac ttctttagta aatgtacctg
     5461 ttatagcatc tggaggcgct ggaaaaaagg aagattttta tgaggcggtt aataaatcca
     5521 atgtagatgg aattttagca gcatctgttt ttcattttgg cgagataaaa ataaacgatt
     5581 taaagaaata tttaaaagac atgggtgtag aagtaagatt ataagttaaa tactaaaagg
     5641 agattagaaa tatggataat aagtgtaaca atgtatacag tgatgaagta gagaaattta
     5701 taagaagtat aaagtttgat gataaagggt tagtccctgt tgttgttcaa gaggtagtta
     5761 gcaaagatgt actgatgtta gcatatatga ataaagatgc tataaagaaa accttaaaag
     5821 ataaagtagc ttgctatttt agtagaagta gacaagaact ttgggttaaa ggtgagacat
     5881 ctggtaatac tcaaaaagta gttaagatgt cttatgattg tgatgtagat actatactac
     5941 tttttgttga acaaactggt gtagcttgtc atacaggcaa ttattcttgt ttttacagag
     6001 acttgtttga tgatagttca aaaatggagc ttgaagtaca aacaaatata ttgaaagaat
     6061 tatatgattt aatcaatgaa agaaaaaata atccagttga aggttcttat actaattatc
     6121 tttttgaaaa aggaatagat aagattctta aaaaagtagg tgaagagagt agtgaggtaa
     6181 ttatagcatc aaaaaatacc gataaaagtg aacttattta cgaaattagc gatttagtat
     6241 atcatacatt ggttttaatg atagaaaaag gtgttgaaat tgatgaaata aaaaaagaat
     6301 tacttaaaag aagaaaatag aataagatag attaatgggt aataagaaaa tataccgctt
     6361 ttaataaaaa gtggtatatt ttttat
//
LOCUS       DAMKNB010000139         6263 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.145, whole genome shotgun sequence.
ACCESSION   DAMKNB010000139 DAMKNB010000000
VERSION     DAMKNB010000139.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6263)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6263)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6263
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.145"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            210..1232
                     /locus_tag="PC494_003462"
     CDS             210..1232
                     /locus_tag="PC494_003462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HDF3913916.1"
                     /translation="MKNLLEIQKKLIPQAIELMERRYSILRQISLSEPIGRRTLSNVL
                     EISERIIRSETEFLKEQGLIDVAVSGMTITKEGSDLLDKLKDIMSDIMGLSKLQDRVR
                     EKLGIKRVILVPGSCDENGSLLKDVTRYGCEYFLGILKDGDIVSITGGSTMLEFSNVI
                     KTDKRYPNSTIVPARGSMGTDVEMQSNNIVASISKKLHSNCKLLHIPDELDESAMKTL
                     SQVPEIKTTLEYIKRTDILVFSIGRADVMAKRRKLPEDKVDEILSKNAVGEAFGYYFN
                     KDGEIVYKLNTVGIDLETVKQVKETIAIFAGTEKVEALLAISNMHKNMVLVTDEESAY
                     KILSLL"
     gene            1292..2299
                     /gene="gap"
                     /locus_tag="PC494_003463"
     CDS             1292..2299
                     /gene="gap"
                     /locus_tag="PC494_003463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HDF3913917.1"
                     /translation="MVKVAINGFGRIGRLALRKMMEQQDKFEVVAINDLTDAKMLAHL
                     FKYDTAQGRFNGEIEVKEGAFVVNGKEIKVTAERNPADLPWAELGVDIVLECTGFFTS
                     KDKAEAHIQAGAKKVVISAPATGDLKTIVFNTNSDILDGSETVISGASCTTNCLAPMA
                     KVLNDKYGIEKGLMTTIHAYTNDQNTLDGPHPKGDLRRARAAAGNIVPNTTGAAKAIG
                     LVIPSLKGKLDGAAQRVPVVTGSITELVCTLGKNVTVEEINAAMKEASNESFGYTEEM
                     LVSSDIIGISYGSLFDATQTKVMEVDGKQLVKVVSWYDNEMSYTSQLIRTLGYFAQLA
                     K"
     gene            2521..3723
                     /locus_tag="PC494_003464"
     CDS             2521..3723
                     /locus_tag="PC494_003464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HDF3913918.1"
                     /translation="MSMLNKKTIEDIDVCGKKVLVRCDFNVPLQDGVITDENRLNGAL
                     PTIQYLISKGAKVILCSHLGKPKGEAKPELSLAPVAKRLSEMLGKEVVFAADDNVVGE
                     NAKKATEKMENGDVVLLENTRYRKEETKNEENFSKELASLAEIFVNDAFGTAHRAHCS
                     TVGAGEFLQERVCGYLIQKELKFLGEAVANPVRPFTAILGGAKVSDKLAVINELLEKV
                     DNLIIGGGMAYTFLKAQGYEVGTSLLEIDKVEYAKEMMEKAKNKGVNLLLPVDVVMAD
                     HFAPDATPIVTEDANVKEDYMGLDMGPKTIANFVKTIKESKTVVWNGPMGVFEFENFA
                     NGTLSVARAMAELTDATTVIGGGDSAAAVNQLGFGDKMTHVSTGGGASLEFLEGKELP
                     GIAALDNK"
     gene            3749..4492
                     /locus_tag="PC494_003465"
     CDS             3749..4492
                     /locus_tag="PC494_003465"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HDF3913919.1"
                     /translation="MRKPIIAGNWKMHKTIKEALEFVNEVKDKVNSDKVEAVICAPFT
                     LLKDLKEATKGTNIKIGAQNMHFEEKGAFTGEVSPLMLKEIDMDYVVIGHSERRQYFN
                     ETDETVNKKVLKALEVGIDPILCVGETLEQREAGKTKDVCKVQVEKALENVLKDDLAK
                     VVVAYEPIWAIGTGKTATAEDANDVISYIREVIKGLYGELANEVRIQYGGSVKPSNVA
                     EIMGQSDIDGALVGGASLASNDYLDLVNF"
     gene            4501..6033
                     /locus_tag="PC494_003466"
     CDS             4501..6033
                     /locus_tag="PC494_003466"
                     /EC_number="5.4.2.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003228330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-bisphosphoglycerate-independent
                     phosphoglycerate mutase"
                     /protein_id="HDF3913920.1"
                     /translation="MMKKPVALIIMDGFGYNKDVKGNAIAESKTPNLDRIKKEYPNTL
                     INASGLDVGLPDGQMGNSEVGHTNIGAGRIVYQDLTRITKSIKDGDFFTNKVLCEAMD
                     NAKENSLHVMGLLSDGGVHSHIDHLKAIIKMAKDKGVQKVYVHAFTDGRDTDPQSALE
                     YAKEVQASMDEIGVGEFATVSGRYYAMDRDKRWERVELAYNAMVRGIGEKANSIEEAI
                     QNSYDDGKNDEFIMPTVIMKDDKPAGSIKENDSIIFFNFRPDRARQITRALVCEEFDG
                     FKREDIKNFFVCLTEYDITIENVHIAFGPQSLANTLGEYLAKNGKTQLRAAETEKYAH
                     VTFFFNGGVEEPNKGEERLLIPSPKVATYDLKPEMSAYELTDKALDKLGEDKFDFIVL
                     NFANPDMVGHTGSIEAAIKAVETVDTCVGKLIDKIVELGGSAIITADHGNAEYMLDPE
                     TGKTVTAHSINPVPFIVVGQEYESAKLLDGGRLSDIAPTVLDMMKLEKPEEMTGHSLI
                     SK"
BASE COUNT         2509 a          728 c         1254 g         1772 t
ORIGIN      
        1 aaatatatat aaaaagcctt atataaaaag aaaaaatact gtgatttgaa aatggtggag
       61 aaatatttta taaaataaaa aaataaaaaa gtttttgaaa aactattgaa atctatacgc
      121 aaatcctata aaataaaaat atcttgtggg acttaaataa acactaggga caaaaaaagt
      181 cccgaaagga aagcaataag gagtatgtta tgaagaactt attagaaatt caaaagaaat
      241 tgattccaca ggcaattgaa cttatggaaa gaagatactc tattttaaga caaatatctt
      301 taagtgaacc aataggtagg agaacattat caaatgtatt agagattagt gaaagaataa
      361 tcaggtcaga aactgagttt ttaaaagaac aaggacttat agacgtagct gtatctggga
      421 tgactatcac taaagaaggt tctgatttgt tagataaact taaggacatc atgagtgaca
      481 tcatgggatt gtctaagtta caagatagag tcagagaaaa gcttggaata aaaagggtaa
      541 tattagttcc tggaagctgt gatgaaaatg gaagtttact aaaagatgta actagatatg
      601 gatgcgaata tttcttaggc attttaaaag atggagatat cgtttcaata acaggaggaa
      661 gcactatgtt ggagttttca aacgttatta aaactgataa gagatatcca aactctacaa
      721 tagttccagc tagaggaagt atgggaactg atgtagagat gcaatctaac aatatagttg
      781 cttcaataag taagaaatta cattctaatt gcaaactttt acatatacca gatgagttgg
      841 atgaaagtgc aatgaaaact cttagccaag tgccagagat taagacaact ttggagtata
      901 ttaaaagaac agacatttta gtttttagta taggtagagc agatgtcatg gcaaagagaa
      961 gaaaacttcc agaagacaag gttgatgaga tattatctaa aaatgcagtt ggagaagcat
     1021 ttggatatta tttcaacaaa gatggagaaa tagtttacaa actgaacact gttggaattg
     1081 atttagaaac agttaaacaa gtaaaagaaa ctattgcaat ctttgcaggg actgaaaaag
     1141 tagaagcctt attagctata tcaaatatgc ataaaaacat ggttcttgta acagatgaag
     1201 aaagtgctta taagatattg tcattattat aaaagtcaag acctagcaca gagctagaaa
     1261 acatacattt actttatagg aggtagcgaa aatggttaaa gtagctataa atggatttgg
     1321 aagaatagga agattagcat taagaaaaat gatggagcaa caagataagt tcgaagttgt
     1381 tgcaataaac gacttaacag acgctaaaat gttagctcat ttatttaaat atgatacagc
     1441 tcaaggaaga tttaacggag aaatagaagt taaagaaggt gcttttgtag taaacggaaa
     1501 agaaataaaa gtaacagcag aaagaaatcc tgctgaccta ccatgggctg aattaggagt
     1561 agatatagta ttagaatgta caggattctt tacatctaaa gataaagctg aagctcatat
     1621 acaagcaggg gctaagaaag ttgttatatc tgcaccagct actggagatt taaaaacaat
     1681 agtattcaac acaaacagtg acatattaga tggttctgaa acagttatat caggagcttc
     1741 ttgtactact aactgtttag ctccaatggc taaagtatta aatgataaat acggtataga
     1801 aaaaggatta atgactacta tacatgcata cactaatgac caaaatactt tagatggtcc
     1861 tcatccaaaa ggtgatttaa gaagagctag agctgctgct ggaaacatag ttccaaacac
     1921 tacaggagct gcaaaagcaa taggcttagt aataccttca ttaaaaggaa aattagatgg
     1981 ggcagcacaa agagtaccag ttgtaactgg ttcaataact gaattagttt gtacattagg
     2041 aaaaaatgtt acagttgaag aaataaatgc agctatgaaa gaagcttcaa acgaatcttt
     2101 cggatatact gaagaaatgt tagtatcttc tgacataatc ggaataagct acggttcatt
     2161 atttgacgct actcaaacaa aagttatgga agtagatgga aaacaattag ttaaagttgt
     2221 ttcttggtat gataatgaaa tgtcttatac ttctcaatta ataagaactt taggatactt
     2281 tgcacaatta gcaaaatagt cagttttgag aaaatagaaa agtagattga caaagtccga
     2341 gtttgtagtt taatactacg gactcaggac tttttttaag aaaaaatata taaaatacac
     2401 ctaaataatg ttacatacta tatataaaaa tatgataata tgatatattt aatagggtaa
     2461 aagtatgtac tatattatac ttggcaataa aaaattactt tattaaaagg agagatattt
     2521 atgtcaatgc ttaacaaaaa aactatagaa gatattgatg tgtgcggaaa aaaagtatta
     2581 gtaagatgtg actttaatgt gccattacaa gatggtgtaa ttactgatga aaatagattg
     2641 aacggagctt taccaactat tcaatattta atttctaaag gggcaaaagt tatattatgc
     2701 tctcacttag gaaagccaaa aggagaagct aaaccagaat tatctttagc accagtagca
     2761 aagagattat ctgagatgtt aggaaaagaa gttgtatttg cagcagacga taatgttgta
     2821 ggagaaaatg caaagaaagc aactgaaaaa atggaaaacg gagatgtagt attattagaa
     2881 aatactagat atagaaaaga agaaactaaa aacgaagaga atttctctaa agaactagca
     2941 tcacttgctg aaatatttgt aaatgatgca tttggaactg ctcatagagc acattgctca
     3001 acagttggtg caggcgagtt tttacaagag agagtttgtg gatacttaat tcaaaaagaa
     3061 ttaaaattct taggagaagc tgttgcaaac cctgtaagac catttacagc tatacttgga
     3121 ggagctaaag tttctgataa attagctgtt ataaacgaat tattagaaaa agttgataat
     3181 ctaataatag gtggaggaat ggcttataca ttcttaaaag ctcagggtta tgaagtagga
     3241 acttctttac ttgaaataga taaagttgaa tatgctaaag aaatgatgga aaaagctaag
     3301 aataagggtg ttaacttatt attaccagta gacgttgtta tggcagacca ctttgcacca
     3361 gatgctactc caatagtaac agaagatgct aatgtaaaag aagattacat gggactagat
     3421 atgggaccta agactatagc aaactttgta aaaactataa aagaatcaaa aactgtagta
     3481 tggaatgggc caatgggagt atttgaattt gaaaactttg caaatggtac attatcagta
     3541 gctagagcta tggcagagtt gactgatgca actactgtaa ttggcggtgg agatagtgca
     3601 gcagcagtta atcaattagg atttggtgac aagatgactc acgtatcaac aggtggagga
     3661 gcatcactag aatttttaga aggtaaagaa ttaccaggta ttgcagcatt agataataaa
     3721 taaactaata tatagaggag attgtaaaat gagaaaacct ataattgcag gaaactggaa
     3781 aatgcataaa acaataaaag aagctttaga atttgtaaat gaagttaaag ataaagtaaa
     3841 ttctgataaa gtagaagctg ttatatgtgc accatttact ttattaaagg atttaaaaga
     3901 agctactaag ggtacaaata taaagatagg tgctcaaaat atgcactttg aagaaaaagg
     3961 agcatttaca ggagaagttt cacctcttat gttaaaagaa atagatatgg actatgttgt
     4021 aataggacat tcagaaagaa gacaatactt caatgaaact gatgaaactg taaacaagaa
     4081 agttttaaaa gcattagaag taggaataga cccaatatta tgtgttggag aaactttaga
     4141 acaaagagaa gctggaaaaa ctaaagatgt ttgtaaagtt caagttgaaa aagctttaga
     4201 aaatgttctt aaagatgatt tagcaaaagt agttgttgca tatgagccaa tctgggctat
     4261 tggaactggt aaaactgcaa ctgctgaaga tgctaatgac gttatatctt atataagaga
     4321 agttataaaa ggattatatg gagaattagc taatgaagtt agaatacaat acggtggaag
     4381 tgttaaacct tcaaatgtag ccgaaataat gggtcaaagt gatatagatg gagctttagt
     4441 aggtggagct agtttagcta gtaatgatta cctagacctt gttaatttct aaggagtgaa
     4501 atgatgaaaa aaccagttgc tttaattatt atggacgggt ttggatacaa taaggatgtt
     4561 aagggaaatg caattgctga gtccaaaact cctaatttag atagaataaa aaaagagtat
     4621 ccaaacacat tgataaatgc tagtggtctt gatgttggtc tacctgatgg tcaaatggga
     4681 aattcagaag ttggacacac taacataggt gcaggtagaa tagtatatca agatttaact
     4741 agaataacaa aatctataaa agatggtgac ttttttacta ataaagtttt atgtgaagca
     4801 atggataatg caaaagaaaa ttctcttcat gtaatgggac ttttgtctga tggaggagta
     4861 cattcacata tagaccatct taaggctata atcaaaatgg caaaagataa aggcgtacaa
     4921 aaggtgtatg ttcacgcatt tactgatggt agagatactg accctcaaag tgcattagaa
     4981 tatgccaaag aagtacaagc tagtatggat gaaattggag taggtgaatt tgctacagtt
     5041 tctggtagat actacgctat ggatagagat aagagatggg aaagagtaga acttgcatac
     5101 aatgccatgg ttagaggtat tggtgaaaaa gcaaattcta ttgaggaagc tattcaaaac
     5161 tcttatgatg atggaaaaaa tgatgagttt ataatgccaa cagttattat gaaagatgat
     5221 aaaccagctg gaagtataaa ggaaaatgat tcaattatat tcttcaactt tagaccagat
     5281 agagctagac aaataactag agctttagtt tgtgaagagt ttgatggatt taaaagagaa
     5341 gatattaaaa acttctttgt atgcttaaca gagtacgata taactataga gaatgtgcat
     5401 atagcatttg gacctcaatc tttagccaac actctaggtg agtatctagc taaaaatgga
     5461 aaaactcaac ttagagctgc tgaaactgaa aagtatgcac atgtaacttt cttcttcaat
     5521 ggtggagtag aagagccaaa taaaggtgaa gaaagactat tgataccttc tccaaaggtt
     5581 gcaacttatg atttaaaacc agaaatgtca gcatatgaat tgacagataa agctttagat
     5641 aaattaggag aagataagtt tgactttata gtattaaact ttgcaaatcc tgatatggta
     5701 ggtcatacag gaagtataga agcggctata aaggctgttg aaactgtaga tacttgtgta
     5761 ggaaaattga tagataaaat agtagagttg ggtggaagtg caataataac tgctgaccac
     5821 ggaaatgctg aatatatgtt agacccagaa acaggaaaaa ctgtaacggc tcactctatt
     5881 aatccagtac catttattgt agttggtcaa gaatatgaaa gtgcaaaatt attggatgga
     5941 ggaagattat ctgatatagc accgactgtt ttagatatga tgaagttaga aaagccagaa
     6001 gaaatgactg gtcattcact tatttcaaaa tagtcgattt tgataagtag agaataatat
     6061 ataaactaca atataaattt aaaaataatg cagtttaggt ttattttgta aagtttagac
     6121 tttatgacat aagatttaaa ttttgtaagt tctggatatt gtaaggtgta gatgaagata
     6181 tattttataa aatttacaag atagacaatt tataaaataa aaaattacaa tatagataat
     6241 aatgtaaata atgatataaa taa
//
LOCUS       DAMKNB010000140         6193 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.146, whole genome shotgun sequence.
ACCESSION   DAMKNB010000140 DAMKNB010000000
VERSION     DAMKNB010000140.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6193)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6193)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6193
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.146"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            311..1678
                     /locus_tag="PC494_003467"
     CDS             311..1678
                     /locus_tag="PC494_003467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase"
                     /protein_id="HDF3913921.1"
                     /translation="MGLKEFDFIEESIDMLRTMSPTLETISDEIEEYFENILDEKNQE
                     YINVTSRIKSESSLREKIIRNRYLKKYGEASNLIHNVSDLIGLRIECRFIEDENKIYR
                     LLRRYFNKTDDKINYYNKENKNIKLKLSERQPNKQKNGFEIYKIDGVFAYLDREVKFE
                     LQIKSLVNVFWSEIEHKIIYKNNTYLLADKFIKDMMDSIKNNLTMIDNQLLSIYKNFH
                     SGKSFNMKVSKKEIEKLFAKLVYDAFSEKMNKSIGFVVDFKKPCETILNYSFNKQDIS
                     DEVLGNFMLDEFARLNEIVNKDIDFNEQIEFEREPTFDDKFCKDLGNHFRSRLNTEFP
                     WNLFFRILFEIEPYNNTKDFENFVEFIKENVLLEENREQLLCQFEEDSKLIIEDIYDC
                     IFNSISEIDSVEILYNYNLEKINFTSSEIINCICREYECYGEYLEEKEKLMNTFKEKI
                     IQIFE"
     gene            1703..2311
                     /locus_tag="PC494_003468"
     CDS             1703..2311
                     /locus_tag="PC494_003468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdenum cofactor guanylyltransferase"
                     /protein_id="HDF3913922.1"
                     /translation="MRHFSNIYELSKIILEEAICIEKTGVILAGGKNSRMGRDKAFLE
                     LHDKLFIEIAIEAFKNFDELIIISNNEELYSKYDIKVYNDIVKDVGPIGGIYTALEYA
                     KYDIVTIACDMPYLNNQIVERIANKMDDKSVISVTNGKLQPLCSGYKKSIINKVSLCI
                     RENDLKLRSFIDKIDKSYIYFDEEDLFLNVNTVDEYKKLTKV"
     gene            2359..2730
                     /locus_tag="PC494_003469"
     CDS             2359..2730
                     /locus_tag="PC494_003469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HDF3913923.1"
                     /translation="MNLLKCDSWAVILNNSDKESKAYKILDELKRNMYKVVAIDEEKK
                     PIEGIDVYECLKDVPHNIDVVAIIDKQSKMDVILEEVELLDIQNMWFEKGSFSEMMIK
                     KTKDLKLNIEYNLSLYDELTR"
     gene            2909..3247
                     /locus_tag="PC494_003470"
     CDS             2909..3247
                     /locus_tag="PC494_003470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal-binding domain-containing protein"
                     /protein_id="HDF3913924.1"
                     /translation="MLIVTTEKVEGKKISKVLGLVRGSTIRAKHVGKDIGASFKNLVG
                     GELTGYNEMLTEARQIAIGRMVEDAEAKGANAVIAFRLSSASVMQGAAEMLAYGTAVV
                     LEDDNSILEK"
     gene            3713..4216
                     /locus_tag="PC494_003471"
     CDS             3713..4216
                     /locus_tag="PC494_003471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MogA/MoaB family molybdenum cofactor
                     biosynthesis protein"
                     /protein_id="HDF3913925.1"
                     /translation="MFNVAIITLSDKGYEGKREDITGKKLTEFVENTGVYKVTEYVLI
                     KDDKEMLKENIIRLCNSNKIDLILTNGGTGFSKRDITPEATKEVLEKEIPGLSEYMRM
                     KSTEITKKAILSRGVSGIRNNSIIINLPGSPKGAVENLSFIIDVLDHGIEVLRGEATE
                     CATKKSE"
     gene            4263..5222
                     /gene="moaA"
                     /locus_tag="PC494_003472"
     CDS             4263..5222
                     /gene="moaA"
                     /locus_tag="PC494_003472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP 3',8-cyclase MoaA"
                     /protein_id="HDF3913926.1"
                     /translation="MIDKYGRKIDYLRISLTDKCNLRCVYCMPPDVKFDKNYINENLS
                     FEDYKFIIKAMAEQGITKIRFTGGEPLLYPKLNELIKFTKEECGINNIGMTTNAIGLS
                     DRIFELEKCGLNKVNISLDSLKEYKYKSITRGGNLKDVLKSIESCLNLGIKVKLNCVA
                     ISGFNDDELKDFMFLTVKSPIDVRFIELMPLGEANRVYKKGYFNVKEMIEKIYGLYKV
                     KNDEKSTAEYYMFKGAKGRIGIITPLSCSFCNTCNRIRLTSSGAIKLCLHSKEEIDIK
                     PFLHKPLLFRESMKDIIKQKPEKHHLIENKCSDTNRRMYEIGG"
     gene            5226..5696
                     /gene="moaC"
                     /locus_tag="PC494_003473"
     CDS             5226..5696
                     /gene="moaC"
                     /locus_tag="PC494_003473"
                     /EC_number="4.6.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic pyranopterin monophosphate synthase MoaC"
                     /protein_id="HDF3913927.1"
                     /translation="MLTHINEKGYAKMVDISEKDDTKRTAVATATITLSKEALEKVKN
                     GQIKKGDVLSVAQVAGIMGAKNTSSNIPMCHQIKLVGCDLEFDVDDSMSAIKIYATCK
                     SLGKTGVEMEALNACSLAALTIYDMCKAVDKKMVISNIHLVEKTGGKSGDFKFE"
     gene            5732..6163
                     /locus_tag="PC494_003474"
     CDS             5732..6163
                     /locus_tag="PC494_003474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MOSC domain-containing protein"
                     /protein_id="HDF3913928.1"
                     /translation="MAKVVSINISEKKGVIKVPVQCAELKINHGIVGDAHAGNWHRQI
                     SLLGKESIDKMKMKGFDQLKYGDFAENVTTEGIEVFSLPVGTKLRIGQCEVEVTQIGK
                     KCHNGCEIKKLTGDCVMPREGIFVKVLKEGIINVNDSIDVI"
BASE COUNT         2619 a          504 c         1120 g         1950 t
ORIGIN      
        1 atttcatata acaatgcaaa aaataatttt tatatagtaa atgacaaaag tttacaataa
       61 atgtatattt tcttactcat tccttaaaat tactcattta gtttaataac tctcatttca
      121 tatgtaaagt tggtaaaaaa attaaaatta aaagtaaaaa actaaataaa ttaatgttaa
      181 tttgaaatat atatgaaggt ttttggagaa tacttactta tgataggaaa aaatgttaaa
      241 ataatagtgt aatcaaatat aaaggactga aataattaac agttattaaa tattaggagt
      301 gtaaaaattt atgggattaa aagaatttga ttttattgaa gagtctattg atatgttgag
      361 gacaatgtca ccaacattag aaactatatc agatgaaata gaagaatatt ttgaaaatat
      421 cttggatgaa aagaatcaag aatatataaa tgtaacctct agaataaaat cagaatcaag
      481 tttaagagaa aagataatta gaaatagata tttaaaaaaa tatggagaag caagtaatct
      541 tattcataat gtttctgact taataggcct aagaattgag tgtagattta ttgaggatga
      601 aaacaaaata tatagacttt tgagaagata ttttaataaa acagatgaca aaataaacta
      661 ttataataaa gagaataaga atattaaatt aaaactatct gagaggcaac ccaataagca
      721 aaaaaatgga tttgaaatat ataaaataga tggagttttt gcgtatttag atagagaagt
      781 aaaatttgaa cttcaaatta aatctcttgt aaatgtgttt tggagtgaaa tagaacataa
      841 aataatttat aaaaacaata catatttact tgctgataaa tttataaagg atatgatgga
      901 ctctataaag aataatctta ctatgataga taatcagctt ttaagtattt ataaaaactt
      961 tcattcaggg aagtctttta atatgaaagt aagtaaaaaa gaaattgaaa aattatttgc
     1021 gaaactagtc tatgacgctt tttctgaaaa gatgaataaa agtataggtt ttgttgtaga
     1081 ttttaaaaaa ccatgtgaga ctatattgaa ctattctttt aataaacaag atataagtga
     1141 tgaagtttta ggtaatttta tgcttgatga gtttgcaaga ttaaatgaaa ttgtaaacaa
     1201 ggatatagat tttaatgagc aaatagaatt tgaaagagaa ccaacatttg atgataagtt
     1261 ttgtaaagac ctaggaaatc attttagaag tagattaaac acagaatttc catggaacct
     1321 attttttaga atattatttg aaatagagcc atataacaat accaaagact ttgaaaactt
     1381 tgtagagttt ataaaagaaa atgtgctact agaagaaaat agggagcaat tattatgcca
     1441 atttgaagag gatagtaagc ttataattga agatatatat gattgtatat ttaatagtat
     1501 aagtgagatt gatagtgttg aaattttata taactataat cttgaaaaaa taaactttac
     1561 atcaagtgaa atcataaatt gtatatgtag agaatatgag tgttatggtg aatacttaga
     1621 agaaaaagaa aagcttatga atacatttaa agaaaagatt attcaaatct ttgagtaata
     1681 ggtcaatgct gaagtggcgc taatgcgcca tttttcaaat atatatgaat taagtaaaat
     1741 tattttggag gaggcgattt gtatagagaa aacaggtgta attttggcag ggggaaaaaa
     1801 ttctagaatg ggtagagata aagccttttt agagttacat gataagcttt ttattgaaat
     1861 tgcaatagaa gcatttaaaa actttgatga gttgataata atatctaaca atgaagaatt
     1921 atattctaaa tacgatatta aagtttataa tgatatagta aaagatgttg gtccaattgg
     1981 aggaatatat actgctcttg aatatgcaaa gtatgatata gttacaattg catgtgatat
     2041 gccatatcta aataatcaaa tagtcgaaag aatagctaat aaaatggatg ataaaagtgt
     2101 gatttcagtg acaaatggaa agttacaacc attgtgttct ggatataaaa agagtataat
     2161 aaataaagta tctttatgta taagggaaaa tgatttaaag ctcagaagct ttatagataa
     2221 aatagataaa agttatatat actttgatga agaagattta tttttaaatg taaacactgt
     2281 tgatgagtat aaaaaattaa ctaaagttta attagctatg gttgtaaaat agagtaggat
     2341 ttatatggag gagagtttat gaatttactt aaatgcgatt cttgggcagt aatattaaat
     2401 aatagcgata aagaaagtaa agcatataaa atattagatg aacttaaaag gaatatgtac
     2461 aaagttgttg ctatagatga agagaaaaaa cctattgaag gaatagatgt gtatgaatgt
     2521 ttaaaagatg ttccacacaa tattgatgtt gtagctatta ttgataaaca atctaagatg
     2581 gatgtgattt tagaagaagt agagcttttg gatatacaaa atatgtggtt tgaaaaagga
     2641 agctttagtg aaatgatgat taaaaagact aaagatttaa aattaaatat agaatataat
     2701 ttaagtttat atgatgagtt gactagataa aattatattt cttaataata aaaatataat
     2761 tagttaataa aacatattat tttatagtat agattggtta ataaaagtac agattggtta
     2821 atgaaacatt aaattacaat atttgttaaa aaaattgtga gttacatgat ataatgtatt
     2881 aaataggata ctaaggagtt gatatattat gttaatagta actacagaaa aagtagaagg
     2941 taaaaagata tcaaaggttt taggattagt gagaggaagt acaataagag caaaacatgt
     3001 tggaaaagat ataggagcaa gttttaagaa tcttgttgga ggagaactta ctggatataa
     3061 tgaaatgctc actgaagcaa gacaaattgc cataggtaga atggttgaag atgcagaagc
     3121 taaaggtgca aacgcagtaa tagcatttag actgtcttca gcttcagtta tgcaaggagc
     3181 agcagaaatg cttgcttatg gaacagcagt tgttttagaa gatgataata gtattcttga
     3241 aaaataaaat ataaatagtt aaaaagaggc atcttttaaa aattttatgg atgccttttt
     3301 ttatttgaaa aaactaattt gagaagaaat tttaactatt atgacaataa aattagggtg
     3361 atattatata aataagtaaa attatattat ataatgtatg gtatagactt taaaaatttt
     3421 atttgtagag aaaaatatgg acaatgttat aataattata gaaattaaaa gtacttacat
     3481 tcattatgta tgtgacatgt ataattagtt ttatatttaa tacagttttg aagtaatatc
     3541 ttcattttga gaacgttgga ataataaaaa atgtattatt ataggtgata taaataaaaa
     3601 ataaatataa tatgttatat tgctgataga aaagagaata aaagaaaata ggttttatta
     3661 aaagagattt ttatttatag gacttaatca atgtatagag gggtgagaac atatgtttaa
     3721 tgttgcaatt ataacactta gtgataaagg atatgaagga aaaagagaag atataacagg
     3781 aaaaaagtta actgaatttg ttgaaaatac aggagtttat aaagttactg aatatgtact
     3841 tataaaagat gataaggaaa tgctaaagga aaatattata agactttgta atagtaataa
     3901 aatagattta attcttacaa atggaggtac tggtttttca aaaagagata taaccccaga
     3961 agcaactaag gaagtgttgg aaaaagaaat accaggtctg agcgaatata tgagaatgaa
     4021 atccacagaa attactaaaa aggccatact aagtaggggt gtgagtggaa taagaaataa
     4081 ttctataata ataaatttac ctggaagtcc taaaggtgca gttgaaaatc taagttttat
     4141 aattgatgtt ttagaccatg gcatagaagt tttaagagga gaagctacag aatgtgccac
     4201 taaaaaaagt gaatagtata taatctagat agataaaaaa tagacaaaga ggtagataaa
     4261 gtatgattga taagtatgga agaaaaatag actaccttcg tatttcactt acagataagt
     4321 gtaatttaag gtgtgtctat tgtatgccac cagatgtaaa atttgataaa aattatataa
     4381 atgaaaatct aagctttgaa gactacaagt ttattataaa ggctatggct gaacaaggta
     4441 taacaaaaat tagatttact ggaggagaac ctcttttata tcctaaatta aatgagctta
     4501 taaaatttac aaaagaagaa tgtggaataa ataacatagg aatgaccact aatgctattg
     4561 gtctttctga tagaattttt gagcttgaaa aatgtggctt aaataaagtt aatataagtt
     4621 tagattcttt gaaggaatat aagtataaat ccataacaag aggaggaaac ttaaaagatg
     4681 tcttaaaatc gattgaatct tgtttaaatt taggtataaa agtaaagtta aattgcgttg
     4741 ctataagtgg gtttaatgat gatgagctta aagattttat gtttttaaca gttaaatcac
     4801 caattgatgt aagatttata gagcttatgc cattaggtga ggctaataga gtttataaga
     4861 agggttattt taatgtaaaa gaaatgattg aaaaaatata tggtttatat aaagtcaaaa
     4921 atgatgaaaa aagtacagca gaatattata tgtttaaagg agctaaagga agaataggaa
     4981 ttataactcc attaagctgt tcattttgta acacttgtaa tcgtattaga cttacttcta
     5041 gtggtgcaat aaaattatgt ctacattcaa aagaagaaat agatataaaa ccatttttac
     5101 ataaaccatt gttatttaga gaatctatga aagatataat aaaacaaaaa ccagaaaaac
     5161 atcatttaat agaaaataaa tgtagtgata caaataggcg tatgtatgaa attggaggat
     5221 aagtaatgtt aacacatata aatgaaaaag ggtatgccaa gatggtggac ataagtgaaa
     5281 aagatgatac taaaagaacg gccgtagcta cagctacaat tactcttagt aaggaagcat
     5341 tagaaaaagt aaaaaatggt cagataaaaa aaggagacgt attgtctgta gctcaagttg
     5401 caggtataat gggagctaaa aatacatctt caaacatacc aatgtgccat cagattaaat
     5461 tagttggatg tgatttagaa tttgatgtag atgattctat gtctgctatt aagatatacg
     5521 caacctgtaa atctcttggg aaaactggag tagaaatgga agctttaaat gcatgttctt
     5581 tagcagcact tacaatttat gatatgtgta aagcagttga taaaaaaatg gttataagta
     5641 atatccatct tgtggagaag actggtggaa aatcaggaga ttttaagttc gagtaaatta
     5701 ataatatatt gggttaaaat ttggaggaaa tatggcgaag gtagtgtcaa taaatataag
     5761 tgagaaaaag ggtgtaatta aagttcctgt acaatgtgca gagctaaaaa taaatcatgg
     5821 gatagttgga gatgcacatg caggaaactg gcatcgtcag ataagcttac ttggaaaaga
     5881 aagcatagat aaaatgaaaa tgaaaggctt tgaccaatta aaatatggag attttgctga
     5941 aaatgtaact acagaaggga tagaagtttt ttccctgcct gttggtacaa agttaagaat
     6001 agggcaatgt gaagttgaag taactcaaat agggaaaaaa tgtcacaatg gatgtgaaat
     6061 taagaaattg acaggtgact gtgtgatgcc acgagaagga atttttgtaa aggttctaaa
     6121 agaaggaatt ataaatgtga atgattcaat agatgtaatc taatgaagtc actattaaaa
     6181 tataattata agt
//
LOCUS       DAMKNB010000141         6185 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.147, whole genome shotgun sequence.
ACCESSION   DAMKNB010000141 DAMKNB010000000
VERSION     DAMKNB010000141.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6185)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6185)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6185
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.147"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            complement(263..784)
                     /locus_tag="PC494_003475"
     CDS             complement(263..784)
                     /locus_tag="PC494_003475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003442791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF3913929.1"
                     /translation="MIPLLILGLLKQNPNSYGYELLALMEKKHYKYIVNFTKGSFYYN
                     LQQLEEKKFIEKVENKQSNKNRETHNYIITELGCQEFEKLMYKYGSKTEYINLSFYAT
                     LLFANDYKNEKLIELLETQIKQTQVRISLLNESIENDKTNSHYFNRMLENSRSHHLVN
                     IEWFEKLLNDIRD"
     gene            complement(836..1684)
                     /locus_tag="PC494_003476"
     CDS             complement(836..1684)
                     /locus_tag="PC494_003476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003442793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sialate O-acetylesterase"
                     /protein_id="HDF3913930.1"
                     /translation="MIKSFLMLGQSNMAGRGFISEVTPIYNERIQMLRNGRWQMMTEP
                     INYDRPVSGVSLAASFADAWCCENQEDRIGLIPCAEGGSSLDEWNIDGILFKHAISEA
                     KFAIQSSELTGILWHQGENDSNNGNYKFYYKKLLSIIETLRKELNIPDIPIIIGGLGD
                     FLGKVGFGKSCTEYVFINQELQKFAFEQDNCYFVTATGLTSNPDGIHIDAISQRKFGL
                     RYFEAFHKKKHIMEALANESELIIPSNSKTYTKTEKIYINSMDLALGKISYDEFESKL
                     IKLNDN"
     gene            complement(1834..2115)
                     /locus_tag="PC494_003477"
     CDS             complement(1834..2115)
                     /locus_tag="PC494_003477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3913931.1"
                     /translation="MPNIEKDLDGTTTITYLNDDIGVPTDENGYKISMTILHGKTICH
                     VVSPETILGRKFTLEEKQEKDTIIYGAIEKIMVDRQLQIKNSNKEVASH"
     gene            2500..3354
                     /locus_tag="PC494_003478"
     CDS             2500..3354
                     /locus_tag="PC494_003478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HDF3913932.1"
                     /translation="MEWIERLNKAINYIEENITKEIEYEQVAKIACCSTYHFQRMFAY
                     MADVPLSEYIRRRRMSLAAVELQNDDKKIIDVALKYGYSSPTAFNRAFKSIHGVAPSV
                     IKKREITTLKAFPPISFKISIKGAEEMNYRIEKKEAFRIVGVSQPLHNELEKNFEIVP
                     QMWQKVALDGTLQKLIPMMDSQLQGVLGISICNNSEEWKYFISVSSTKSIDNTLEEYT
                     VPAFTWAIFSGEGQCPQAIQELEKRIVTEWLPTSGYEYDNGPDIELYLNPDPQNAKFE
                     VWIPVVKK"
     gene            3553..5058
                     /locus_tag="PC494_003479"
     CDS             3553..5058
                     /locus_tag="PC494_003479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HDF3913933.1"
                     /translation="MNVAIYLRKSRADEEAEHRGEFETLSRHKTTLLKLAREQNLNVI
                     EIKEELVSGESIEYRPKMLELLGEIKNNNYDAVLVMDIDRLGRGNMQDQGLILDTFKK
                     SKTKIITPRKTYDLNDEFDEEYSEFEAFMARKELKLISRRMQRGKIKSIEEGKFIAQA
                     PPYGYDIKYLNNKERVLVINEDKATVVKIIFDMYLKGDGACKISNYLNELGYKTTTGR
                     TWYEKGIRDIIKNKVYCGYIVWNKVERKRNSSRTRGIEEQIEVKGKHEPIISEDIWNK
                     AQNIRKKRINSPTPNNKITNPLAGIVKCGYCNHTLIAKSNTTSNGYEKYMVCTNCKNK
                     ATKLYILENKILEVLNKWLVNYRLSLKDEKDNSKPENTLEHTLTNLNKELDTLEKQKE
                     RLHDFLEQGIYDNNTFGERLKILLSRIENVREAINKTNIDIEMQKERNTVKTQIVPQL
                     EKILSEYTEEKEPYLKNILLKSVINYAVYKKEPNQKSDDFSLILYPNIPRD"
     gene            5085..5585
                     /locus_tag="PC494_003480"
                     /pseudo
     CDS             5085..5585
                     /locus_tag="PC494_003480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897038.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
     gene            complement(5735..6082)
                     /locus_tag="PC494_003481"
     CDS             complement(5735..6082)
                     /locus_tag="PC494_003481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HDF3913934.1"
                     /translation="MHENKKNLLDGSLAQYNDTAVPKIPVFAGNDITSEVYYFKPNQV
                     LNAHRHPNGEQIFVFLKGEGKMKLGEHECDVKNGDTVFVPTGEWHEITNGSNEEMVAV
                     QITKINAGAEYRG"
BASE COUNT         2309 a          823 c          853 g         2200 t
ORIGIN      
        1 attatctata ccattaatta atactcataa ttaatactta aacaatttta ttatatcaaa
       61 tgtcatactt ttcatcttaa gtgtctgtaa ttcaacaatg aacaacttta tatttataaa
      121 ttttacttac atagtataag tgtcttttaa catcttatat aacaaaaaga cagatattca
      181 attgaaaatt atctgcctta tttttaatct atatatcata catttatata aagtatatat
      241 gtatgttttt ttattattaa aatcaatctc taatatcatt tagcaacttc tcaaaccatt
      301 caatattaac taaatggtga gaacgagaat tttctagcat tctattaaaa taatgtgaat
      361 ttgttttgtc attttctatg gattcattta atagagaaat tcttacttga gtttgcttaa
      421 tttgcgtttc caataattct attaactttt catttttata atcatttgca aataatagtg
      481 ttgcgtaaaa tgatagattt atatactctg ttttagaacc atacttatac attaattttt
      541 caaattcctg gcatccaagt tcagtaatta tgtagttatg agtttctctg tttttattag
      601 attgtttatt ttcaactttt tcaataaact ttttttcttc aagttgctgt aaattataat
      661 aaaaagaacc tttagtgaaa tttactatgt acttgtaatg cttcttttcc attaatgcta
      721 ataactcata tccataagaa tttggatttt gttttaataa tcctaaaatt aataatggta
      781 tcaaaaaatc acctctttca atctatattt attagtatat taatgaatat tttatctaat
      841 tatcattaag tttaataagt ttagattcaa actcatcata tgatatcttt cctagtgcca
      901 agtccatact atttatatat attttttctg tttttgtata tgtcttggaa ttactcggta
      961 ttatcaactc actttcatta gctaatgctt ccataatatg ctttttctta tgaaaagctt
     1021 caaaataacg taatccaaat tttctttgag atattgcatc aatatgaata ccatcaggat
     1081 tagatgtaag acctgttgct gtaacaaagt aacaattatc ttgttcaaaa gcaaatttct
     1141 gtaactcttg attgataaat acatactcag tacaactttt tccaaaacct acttttccta
     1201 agaagtctcc caatccacca ataataattg gtatatctgg aatatttaat tcttttctaa
     1261 gagtttcaat aatagaaagt aattttttat aataaaattt atagttgcca ttattactgt
     1321 cattttctcc ctgatgccat aaaattcctg tcaattcact gctttgtatg gcaaatttag
     1381 cttcacttat agcatgttta aaaagtatac catctatatt ccattcatct aaggaactgc
     1441 ctccctcagc acaaggaatt agcccaattc tatcctcttg attttcacag caccatgcat
     1501 ctgcaaatga tgcagcaaga cttaccccag aaactggtct gtcataatta ataggttctg
     1561 tcatcatttg ccatcttcca ttacgtaaca tctgtattct ttcattataa attggagtca
     1621 cttcacttat gaatcctctt ccagccatat tggactgtcc taacattaaa aatgatttaa
     1681 tcattattat tattatcctt tcttaaattc ttattgtatt tatttttaat agtagtctaa
     1741 ttagactatc tatgtttata ttatagtcta attagactat aagtcaataa tattataaaa
     1801 aatacttgtc ctactttact tattaaagaa gtgctaatga ctagcaactt ctttgtttga
     1861 attttttatt tgtaattgtc tgtctaccat tattttttct attgctccat atattattgt
     1921 atctttttct tgtttttctt ctaatgtgaa ctttcttcct aagattgttt caggagatac
     1981 tacatggcag attgtctttc catgtagtat tgtcatagat attttatatc cattctcgtc
     2041 tgttggaaca cctatatcgt cattgaggta tgttatagta gttgtaccat ctaagtcttt
     2101 ttctatattt ggcatttaaa tcccctcctc tttatatttt atgtatctta aaaattgtcc
     2161 tattctcaat cattatttat aattgagtaa ctaagtgttg cttgattaag ggtaaacttc
     2221 aaaaatagtt aactatgaat aaaatgttat atataattaa atgtctaagc taaaatatta
     2281 taaaaatttc ataataaatt aaaactgtta tcttatataa aaattagata ctaatctgtg
     2341 atatacttta atgtgaaaaa caatactatt tgttcatttt tgtagttaat tacagacttt
     2401 ctcatgttca ttctttatta agctagttaa ttagtgcata gaaagagagg attaactatt
     2461 ttaaaataga tattatataa attacaagga gctgatttta tggaatggat tgaaagatta
     2521 aacaaagcaa ttaactatat tgaagaaaac ataacaaaag aaattgagta tgaacaagtg
     2581 gcaaaaatag cttgttgttc tacatatcat tttcaaagaa tgtttgctta tatggcagat
     2641 gtaccacttt ctgaatatat tcgtcgtaga cggatgtctt tagcagctgt agaattacaa
     2701 aatgatgata aaaagataat tgatgtggct ttaaaatatg gatactcttc tccaacagca
     2761 ttcaaccgtg catttaaaag tattcatggt gttgccccat cagttataaa aaaaagagaa
     2821 ataacaactt taaaagcctt tcctccaatc agttttaaaa ttagtattaa aggagccgaa
     2881 gaaatgaatt atagaattga aaagaaagaa gcatttcgta tagttggtgt atctcagcca
     2941 cttcataatg aactagaaaa gaattttgaa attgttcccc aaatgtggca aaaggttgct
     3001 ttagatggaa cgcttcaaaa attaatccct atgatggata gtcaacttca aggtgtatta
     3061 ggtataagta tttgtaataa ttcagaagaa tggaagtatt ttatatctgt ttcaagtaca
     3121 aaatctatag ataatacatt agaagaatac actgttccag cttttacttg ggcaatattt
     3181 tctggagaag gacaatgtcc acaagcaata caagaactag aaaagcgtat tgtaacagaa
     3241 tggttaccta cttctggtta tgaatatgat aatggtcctg atattgaact gtacttaaat
     3301 ccagaccctc aaaatgctaa atttgaagta tggatacctg tagtaaaaaa atagtttaaa
     3361 attaaaaaat gaagaaagca taaaattaat agtataaata tttacttaga ttacaagctt
     3421 ttaaatatac tataaaattt actgtataaa aataaaccta aaaaatatat cttgtatttt
     3481 gaaggtttat ttttgtgttt taaatataat caatctgtta ctgaatataa tatattcaag
     3541 gggtgtgatt taatgaatgt ggcaatttat ttacgcaaaa gcagagctga tgaagaagca
     3601 gaacatagag gtgaatttga aactctaagt agacataaga caactctttt aaaactagca
     3661 agagaacaaa atttaaatgt cattgaaatt aaagaagaac ttgtttctgg ggaaagtata
     3721 gaatatagac ctaagatgct agaattacta ggtgaaatta aaaataataa ctatgatgct
     3781 gttttagtga tggatattga ccgtttgggt cgtggtaata tgcaagacca agggttaata
     3841 ctagatacat ttaaaaaatc taaaacgaaa attattactc ctagaaaaac gtatgattta
     3901 aatgatgagt ttgatgagga gtattctgaa tttgaagctt ttatggctcg taaggaatta
     3961 aaattaatat ctagacgtat gcaaagagga aaaatcaaaa gtattgaaga gggtaaattt
     4021 atagctcaag ctcctcctta tgggtatgat attaaatatt taaataataa agaaagagta
     4081 cttgtaataa atgaagataa agcaactgtt gttaaaataa tctttgatat gtatttaaaa
     4141 ggagatggtg catgtaaaat atccaattat ttaaacgaac ttggttataa gaccacaaca
     4201 ggtagaactt ggtatgaaaa gggtataaga gatattataa aaaacaaagt gtattgtgga
     4261 tatatagtat ggaataaagt cgagaggaaa agaaattcta gtagaacaag aggaattgag
     4321 gaacaaattg aggtaaaagg aaagcatgaa ccaataataa gtgaagacat atggaataag
     4381 gcacaaaata taagaaaaaa acgtattaat tcccctactc caaacaataa aataacaaat
     4441 ccattggctg gaattgtaaa atgtggatac tgtaatcata ctttaatagc caaatctaat
     4501 actacatcaa atggatatga gaaatatatg gtttgtacta attgtaaaaa taaagctact
     4561 aaactataca tattagaaaa taaaatatta gaggtcttaa ataaatggtt agtaaattat
     4621 agactatctt taaaagatga aaaagataac tctaaacctg aaaatacttt agaacatacc
     4681 ttgacaaatt taaataaaga attggatact ttagaaaaac aaaaagaacg actacatgat
     4741 tttttagaac aaggaattta tgacaataat acatttgggg aacgtttaaa aatactctta
     4801 tctcgtatag aaaatgtaag agaagctatt aataaaacaa atatagatat tgaaatgcaa
     4861 aaggaaagaa atacagttaa aacacaaatt gttcctcaac ttgaaaaaat tttaagtgaa
     4921 tatacagagg aaaaagaacc ttatctaaaa aatatattgc ttaaaagtgt aataaattat
     4981 gcagtctata aaaaagaacc taatcaaaaa tctgatgatt tttctttaat actttaccct
     5041 aatatcccaa gagattaatt atatgtttta aatgttataa atagactgat taccaatttg
     5101 gtgtaatggc tggagctttt gcaggtggag agggtgactt tacaacagca tttgaaccta
     5161 cagcaacagc aatggaaaaa gaaggtagtg gatatatagt cacatctata ggaaaagatt
     5221 ctggagaaat accttttaca gcatactcta ctacgagatc atacatgaaa aacaataaag
     5281 atttaattca aagatttaca aatgctgttt ataaaggtca attatggatt caacaagcat
     5341 ctagcaaaga agtagctaag gctatgcaac ctttctttga agatatatct ttagaagatt
     5401 taacaacagt tgtagataga tataaatcaa tagatgcatg gtctcaaaat cctgtattaa
     5461 aagaggaagg tttgaagaaa ttgatgactg ttatgaaaga agctaaagaa ctagataagg
     5521 aagcacctta taaagatatc gtaaatactg agtttgcaaa caatgctata aaaaatatta
     5581 aataaaatat attagtttta gctagatatt ttcttgtttt tataatgaaa attaacaaaa
     5641 atataaaaag agccttttaa aagactcttt ttatatttga gattaaagtt tatataataa
     5701 aatagatatt aaagtactaa ctgtacttat atatctatcc tctgtattct gctccagcat
     5761 taatttttgt aatttgaacg gctaccattt cttcattgct tccattagta atttcatgcc
     5821 actctcctgt tggtacaaat acagtatcgc cgttttttac atcacattca tgctcaccaa
     5881 gtttcatttt accttctcct tttaggaaca caaatatttg ttcaccatta gggtgtctat
     5941 gagcattaag aacttgatta ggtttaaaat aataaacttc tgaagttata tcgttaccag
     6001 caaatactgg tatttttgga actgctgtat cattatattg agctaagctt ccgtctaata
     6061 gattcttttt attttcatgc atactagaaa tacctctttt ctatattaga tttactatta
     6121 ttataccaat ataagaaaat agtattctca ctttacacaa taggaataaa attcttttat
     6181 tttta
//
LOCUS       DAMKNB010000142         6091 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.148, whole genome shotgun sequence.
ACCESSION   DAMKNB010000142 DAMKNB010000000
VERSION     DAMKNB010000142.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6091)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6091)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6091
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.148"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            172..459
                     /locus_tag="PC494_003482"
     CDS             172..459
                     /locus_tag="PC494_003482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3913935.1"
                     /translation="MKKFLYALYSFIVIIANFRLKEKNYNFILLAIFFILLLIQNGVL
                     KTGYQNRATFYQDNYFNGEDKNDKIKFMTIKIFIFLSLPLCFNILFNYLTS"
     gene            complement(998..1549)
                     /locus_tag="PC494_003483"
     CDS             complement(998..1549)
                     /locus_tag="PC494_003483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF3913936.1"
                     /translation="MSINTVIAKNLNRLRNERNLSLGQLAELSGVSKVMLSQIEKGDS
                     NPTVNTIWKIASGLNVPYTAILEQPQNETFIVSKTDIDVQVSENKDYRLYCYYPNTPT
                     RNFELFQMELEEGHSYTSVGHSEKSQEYIMIIEGQLKLEVNDSIYQLRENDSICFSAE
                     SIHTYHNQGEKTLKAVIINYYPV"
     gene            1740..2702
                     /locus_tag="PC494_003484"
     CDS             1740..2702
                     /locus_tag="PC494_003484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase family protein"
                     /protein_id="HDF3913937.1"
                     /translation="MRVLNNVTEAIGNTHMLHLSKIADEFGVQGNIYAKMEYLNPGFS
                     KKDRVALQMITEAENAGLLVPGQAVVELTSGNTGTGLAIACACKGYKFIACMSKGNSM
                     ERARMMKALGAEVVLVDQMPNSVHGQVSGEDLALVEIEAQKIAKERNAFRADQFNLEA
                     CNHAHEKYTAEEMWEQLDGNIDVFVDFLGSGSTFAGCSKTLKKHNSSIKCYVVEPETA
                     AIYSGKEITDQGHKIQGGGYSMDLPLVDKKLIDGYIQVTDEEATDVARKLAKLEGVFA
                     GFSSGANVCAAIKLLKSSEKGKNIVLTLNDSGLKYLSTDLYEEL"
     gene            2996..4840
                     /locus_tag="PC494_003485"
     CDS             2996..4840
                     /locus_tag="PC494_003485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HDF3913938.1"
                     /translation="MQKRILRNFIFTGKNILSKLVFIIKYNFSTLILFELFHKGLALF
                     FIWPSIRYIFDILIKSLHIVYLNMDNFIKVLTNPMSIVLIILSVIILAFYAFFEFTSV
                     IICFNKSIKYEKIGLFELFKISFENSIKLLYPKNILLFIFVILIIPLVNTVLISGFIG
                     KIQIPEYILDYIKSDIILNIIYMIFLLIIYISVIRWIFSIHEITLNTENFKRARKESV
                     NLIKGKIIRTIIYSLILSLVVAIIGYAIYHSGIIFIGIWTKYCTDMEFLKNVFINRCI
                     AFEEYFRLILSIFIFILDIGFISATYYQYKGVSISKNNIKKEKKSISKIVFNLVLILL
                     ISYIESVAFSSHINGMFNTSFSFYTTAIAHRAGAEMAPENTLAAIEEASHAKADYAEI
                     DVQETKDGELIVLHDSNFKRTTGVDKNVWDVNYNEVKTYDAGSFYYYGKGYYDEKFVG
                     EKIPTLKEKIKYSKGKVKLLIEIKLNGHEKGDVVKKVVQLIKENNFENQCIVASMDKT
                     ILQKVKKLDENLLTCYFMAIAYGDFSKLNYVDIYGIESTFVNKTVVEKIHKMNKKIFV
                     WTVNSDSLIEKMLDLNVDSIITDNPYLIESAIYWKKNGFISQVSDYLF"
     gene            5162..5746
                     /locus_tag="PC494_003486"
     CDS             5162..5746
                     /locus_tag="PC494_003486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HDF3913939.1"
                     /translation="MTEREKMLAGELYDCGDIELLTQWHKAKDLVRDYNQTDSSDLEK
                     KEKILNELLGGKGKNLWITAPYYVDYGNNIYFGNNCEVNMNCTFLDDNKIIIGDNALI
                     APNVQIYTAFHPTNAGDRFGNAKEDGSFEFCKTQTAPVTIGDNVWIGGGAIIMPGVTI
                     GDNVVIGAGSIVTKDIPSNMIAYGNPCRIIRENK"
BASE COUNT         2382 a          596 c          929 g         2184 t
ORIGIN      
        1 aaatttatga atattcatac tataatttaa atataaggag atgccctttg aaaataaaaa
       61 ttaaaaaata tttaatgcta ttacaatagg aactagaact acacttaata aatatacaga
      121 aattagattt ggctcaatat aaaatacaaa tatagaattt aggtgttttt tatgaaaaaa
      181 tttttatatg ctttatatag tttcattgtt attatagcta attttagatt aaaagaaaaa
      241 aattataact ttattttatt agcaatcttt tttatactgc tgttaattca aaatggagtt
      301 ttaaaaacag gttatcaaaa tagagctaca ttttatcaag ataattattt taatggagag
      361 gataaaaatg ataagataaa atttatgact ataaagattt ttatattttt gtcattacca
      421 ttatgtttta atatactatt caattattta acttcttaaa ttatatttag atataggagt
      481 cttatgataa aagtaagctt atgtgttatt tgtagtaaat ataaagtgca tatagtggta
      541 aaacaaaagt ttcatataaa tgaagaaaaa aatataaaat aatttattta actacttaaa
      601 aataaactaa aagggataat aaaatagctt ttaggttatg gtaataaagg tatttaaaaa
      661 gagtgcataa gcactccaat tgtgagaaat acatacacaa atcattatta caacaatgaa
      721 aaatgtacat ataagagacg ttttgtattt gttttaagtg ataatatttt aatactaact
      781 aaataattat cacaatagta aaaaagaaaa aggagtattt tgtactccat ttgtcaaaaa
      841 tataaaactt ttatataagc ttattataac ataattgata aaagtgtaaa gatatataat
      901 gaatttataa agaaaaataa aataaaaaag ataaatccta atcaaaggat ttatcttttt
      961 gtatagaaaa taattattct attattaaat ggcatggcta aactggataa taatttatta
     1021 ttactgcttt caatgttttt tctccttgat tatggtatgt atgaattgat tcagctgaaa
     1081 aacaaataga gtcattttct ctaagttgat aaatagagtc atttacttct aattttaatt
     1141 gaccttctat aatcataata tattcctgtg atttttcaga atgaccaaca gatgtataac
     1201 tatgaccttc ttctaattcc atttgaaata attcgaagtt tctagttggt gtattgggat
     1261 aataacaata aagacgataa tctttatttt ctgaaacttg tacatctata tcagtttttg
     1321 atacaataaa agtttcattt tgaggttgtt ccagtattgc agtatatgga acatttagtc
     1381 cacttgcaat tttccaaatt gtgtttactg ttgggtttga gtctcccttt tcaatttgcg
     1441 aaagcattac tttacttacg ccagataatt cagcaagttg acctagactt aagttacgtt
     1501 cattacgtaa tctatttaaa tttttagcaa taacagtatt aatactcata gtagctcctt
     1561 aaaatgtaaa ttattgacaa atataattta cgaatgtata atttatttaa cattatttat
     1621 aatttacaaa tgtataatat aatgaacgtt aaatacactg tacatccgta atataaatta
     1681 tactgcataa agagttgttt ttcaacggat gatagttgag agattaaggg ggaattgtaa
     1741 tgcgtgtact taataatgtt acagaggcta taggcaatac tcatatgtta catttatcca
     1801 aaatagcaga tgaatttgga gttcaaggta atatttatgc aaagatggaa tacttaaatc
     1861 cgggatttag taaaaaggac cgtgtagcat tacaaatgat taccgaagca gaaaatgcag
     1921 gtttattagt tccaggtcaa gcagttgtgg aattaacaag tggtaatact ggaacaggac
     1981 tagcaatagc ttgtgcatgt aaaggatata aatttatagc gtgtatgtca aaaggaaatt
     2041 ctatggaaag agcaagaatg atgaaagctt taggtgctga agtagttctt gtagaccaaa
     2101 tgcctaattc agttcatgga caggtatctg gtgaagattt ggcacttgta gaaattgagg
     2161 ctcaaaaaat agcaaaagaa agaaatgcat ttagagcaga ccaatttaat ttagaagctt
     2221 gtaatcatgc acatgaaaag tatacagcag aagaaatgtg ggaacaattg gatggaaata
     2281 ttgatgtatt tgtagatttt cttggaagtg gtagtacttt tgcaggatgt tcaaaaacac
     2341 ttaaaaaaca taattcttct atcaaatgtt atgttgttga acctgaaaca gcagcaattt
     2401 attcaggtaa agaaataact gaccaagggc ataaaataca aggtggagga tattctatgg
     2461 atttgccatt agtagacaag aaacttattg atggttatat tcaagttaca gacgaagagg
     2521 caactgatgt agcaagaaaa ttagctaaat tagaaggtgt atttgcagga ttttcttcag
     2581 gggcaaatgt atgtgcagca attaagttgt taaagagcag tgaaaaagga aaaaatatag
     2641 ttttaactct taatgatagt ggtttaaaat atttaagtac tgatttatat gaagaattgt
     2701 aataatagca caatagttat gcaatgtttt ttaaattaag tatatagatt taaattataa
     2761 aaagtatctc aatgtgattt ttgaaagtta taaaggagat acttttttat tttgtaaata
     2821 tggagtatcc tacttataag tattaagcta tatagatatt gatgattagc tatgcaataa
     2881 aaaagagtat ttgttttgca tttatacatc ataacttgga ataatacata ttaatgttct
     2941 aaatgtattt aaaacatatg ataaaattag aacaaacaga tacaaggaga taaacatgca
     3001 aaagagaatt ttaagaaatt ttatatttac gggtaaaaat attttaagta aacttgtttt
     3061 tataataaaa tataatttta gtacattaat tttatttgaa ttatttcata aaggattagc
     3121 cttatttttt atatggccat ctattagata tatatttgat attttaataa aaagtttaca
     3181 tatagtctac ctaaatatgg ataattttat aaaagttttg accaatccca tgtcaatagt
     3241 tctgataata ctatcagtta taatactagc tttttatgca ttttttgaat ttacctctgt
     3301 aattatttgt tttaataaat cgataaaata tgaaaaaata gggttatttg aactctttaa
     3361 aatatcattt gagaactcta taaaattgtt atatcctaaa aatatactat tatttatatt
     3421 tgtgatatta ataattccat tagtaaatac agttttaatt tcagggttta taggaaaaat
     3481 acaaatacca gagtacatac tagattatat aaagtctgat ataattttaa atataatcta
     3541 tatgattttt cttttaataa tatatatttc ggttattaga tggattttta gcattcatga
     3601 gataacttta aatacagaaa attttaaaag agcaagaaaa gaaagtgtta atcttataaa
     3661 gggaaagatt ataagaacaa ttatttattc attaatatta tctttagtag tagctattat
     3721 tggatatgcg atttatcata gtggaattat atttataggc atatggacta aatattgtac
     3781 tgatatggaa tttttgaaga atgtatttat aaatagatgt attgcatttg aagaatattt
     3841 tagattgatt ttgtcaatat tcatttttat attggacatt ggatttatct cagcaactta
     3901 ttatcaatat aaaggagtaa gtatttctaa aaataatatt aaaaaagaga aaaaatctat
     3961 atcaaaaatt gtttttaatt tagtattaat attattaatt tcttatatag agtcagttgc
     4021 attttcttca catataaatg gtatgtttaa tacatcattt tcattttata caacagcaat
     4081 tgctcataga gcaggagctg aaatggctcc agagaatact ttggcagcaa tagaagaagc
     4141 ttcacatgct aaagctgatt atgcagaaat agatgttcaa gaaactaaag atggagaact
     4201 tattgtactt catgattcaa actttaagag aactacagga gtagataaaa atgtttggga
     4261 tgtaaattat aatgaagtaa agacatatga tgcgggaagc ttttattatt atggaaaagg
     4321 ttattatgat gaaaagtttg ttggggaaaa gataccaaca ctcaaagaaa agataaaata
     4381 ttctaaaggt aaggtgaaat tattaataga aataaaactt aatggacatg aaaagggaga
     4441 cgtagtaaaa aaagttgttc agttaattaa agaaaataat tttgaaaatc aatgtatagt
     4501 tgcatctatg gataaaacta tattacaaaa agtaaaaaaa ctggatgaga atttactgac
     4561 atgctatttt atggcaattg catatggtga tttttcaaag ttaaattatg ttgatatata
     4621 tggaattgaa tcaacttttg ttaataaaac agtagtagaa aagattcata aaatgaacaa
     4681 aaaaatcttc gtttggactg ttaatagtga cagtttaatt gagaaaatgc ttgacctaaa
     4741 tgtagatagt attattacag ataatccata ccttatagag agtgcaattt attggaagaa
     4801 aaatggattt attagtcaag tgtcagatta tttattttaa atattctata attgtattat
     4861 ccagtaaaag agatattatt aaaatcaata atatctcttt ttaacataaa taaggttgtt
     4921 aaattaaggt tattcttata aaaattgtgc ttatcagcta taaacaagga ataaaagtga
     4981 aaaaattgct ctgagattat tacagttaaa agagttttaa gatgacagag agatagattg
     5041 tcaactgtat atttaataaa tcttgttatt tattaaattt tatataagta aaatatataa
     5101 attaataaat cttatgctag aatatatatg aaaaacaata taaatttgga ggattaaaaa
     5161 catgacagag cgagaaaaaa tgttggcagg agaactttac gattgtggtg atattgagtt
     5221 gttaactcaa tggcataaag caaaagacct agtaagagat tataaccaaa cagattcctc
     5281 ggatttggaa aaaaaagaaa aaatattaaa tgagttactt ggtggtaagg gtaaaaactt
     5341 atggattact gcaccatatt atgtagatta tggaaataat atttattttg gaaataattg
     5401 tgaagtcaat atgaattgta cgtttttaga tgataataaa attatcattg gggataatgc
     5461 actaatcgca ccaaacgtac aaatatatac tgcatttcat ccaactaatg ctggtgatag
     5521 atttggtaat gccaaagaag atggttcatt tgaattttgt aaaactcaaa cagctccagt
     5581 tactattgga gataatgttt ggattggcgg gggtgctatt atcatgccag gtgttactat
     5641 tggagataat gtagttatag gtgcaggaag tattgttaca aaagatattc caagtaatat
     5701 gattgcatac ggaaatccat gccgtattat tcgagaaaat aaataaagtt aaattttctt
     5761 gcaaaatctc aaaaaatacc tttcttactt tatacatagg gtattttcta atactttcac
     5821 atccatattc atttgttaaa tttttatgga atgtagtttt tatcatctct atcttacatt
     5881 ttcactattt ttttataaaa gtcattcctt tatagattta tttataatag tatatattct
     5941 atttgatgtt tgaataagca cttattttta agtaaaatac taacttttag gttagtattt
     6001 tgctatagta tgatgattaa gtaagaataa aatactataa tacataaagc ttaacaaata
     6061 taatttttat tttacttaga tattttcttt t
//
LOCUS       DAMKNB010000143         5801 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.149, whole genome shotgun sequence.
ACCESSION   DAMKNB010000143 DAMKNB010000000
VERSION     DAMKNB010000143.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5801)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5801)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5801
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.149"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            28..1392
                     /locus_tag="PC494_003487"
     CDS             28..1392
                     /locus_tag="PC494_003487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldehyde dehydrogenase"
                     /protein_id="HDF3913940.1"
                     /translation="MDIKELVKMQRKYYNTGKTRDISFRIEQLKKLKLVVSQNEEKIL
                     LALKKDLNKSDFEGFMTEVGMFYSELNFAIKNIRKWSKIKRVKSSMVNFPSISKVVPQ
                     PYGVTLIMSPWNYPFQLALIPLVWSLAAGNCVILKPSEYSVSTSSVVKDIVEDTFSKE
                     YVAVVQGSQEESEKLLLERFDYIFFTGSTNVGKIIMKSASEHLTPITLELGGKSPCII
                     LKDANIDLTAKRLTWGKLINAGQTCVAPDYVLVHEDRKNELIEKIKYYTNKYFGDNPC
                     NNEQFPKIINQRHFNRILSLIDKDKIVYGGNYNKETLKIEPTIVDNVNWDDNIMKEEI
                     FGPIFPILTYKDLDEVIQKIIQMPNPLALYIFTKNKYLENKLLEMISAGGCCINDTVT
                     HIATNYLPFGGIGESGMGSYHGKAGFDTFTHYKSVLKKLNLDVPIRYAPYDNKLIKVL
                     KKIM"
     gene            1531..2697
                     /locus_tag="PC494_003488"
     CDS             1531..2697
                     /locus_tag="PC494_003488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HDF3913941.1"
                     /translation="MKINWNTKYTTIAIYTFIIAASSIIFYLVSSQIDVFSNNLDAIF
                     TTLQPFIIGFAIAYLLNFILKFYEDRIFIKSEKLKKLKQSSKRGLGLLLTYATATLIL
                     YLFMHFVLPQVIESIVGLANDIPMYVNNATKLIDKLMTDLNLDEQYFNLAVDKWNEFV
                     TYIIKFVTDLIPILGSMLKNVASSIWNIVLGLIVSVYLLIDKEKFYGLSKKITYAVFT
                     EKQAARILELTHRSNYTFGRFLGGKILDSFIIGILTFVILTLVKMPYTLLISVIIGIT
                     NIIPFFGPLFGAIPSTLIVMFVSPIKAFWLLLIILIIQQIDGNIIGPKILGDSIGISA
                     FWILFSLLVAGKLLGFIGMVIGVPMFAVIYSIIKDIVESKLDKKGLPTDTSDYM"
     gene            2814..3596
                     /locus_tag="PC494_003489"
     CDS             2814..3596
                     /locus_tag="PC494_003489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HDF3913942.1"
                     /translation="MAFIECKFKSKYTGGETDIIVILPVANGKELFSGKEIYDFEGKF
                     KTLYLFHGLEDDQSSWIRYTNVEHYAKNKNIALVIPRVETSFYTDMAYGHQYFTFVSE
                     ELPKFVRAIFPLSDKREDNFVAGMSMGGYGALKLALSKPKEFSAVASFSGSPDMIHEL
                     ENQQIETNADILFHDFGRPEDARNSENDLLYILKNLKERNEDIPKIYQFCGDRDFLYK
                     NNQMFKKYADSLGVDVEYEECVGGHEWRLWNLWIKKFIDIIG"
     gene            complement(3715..4368)
                     /locus_tag="PC494_003490"
     CDS             complement(3715..4368)
                     /locus_tag="PC494_003490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDF3913943.1"
                     /translation="MSKSEKGKETKASIISAARELFFEQGYHKTTTRQIAERANINLG
                     LISYYFSSKSEIGAIIYEDIRNEMQSLIYNYHEEGTMMMFFLAMNADLCFLLKNEAYR
                     NFYLDIAYEEAILSYQRSVTEMVMKRYVNDKESIEHDELILSCIGILAMKPEIIRVYT
                     SHKYDISSQAVIKHFTKQFLINLGHSTDLCEEILEELSKYYIDIVDNFTPIITRVRT"
     gene            complement(4392..5756)
                     /locus_tag="PC494_003491"
     CDS             complement(4392..5756)
                     /locus_tag="PC494_003491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:solute symporter family protein"
                     /protein_id="HDF3913944.1"
                     /translation="MLLLIVTCAIYIWIGFYFSKKVKTASDFLIAGRNLPLPILAATI
                     AATSFGGGCLVGGVQWGAERGLWVGMYSTIGAALACFINAFFAGKLRSLSCDITPADY
                     IETRYGHSVFLRAYQSLVTPISILAIMGSQLISFGSVSTAFGIPYDIAVIIGVIVIII
                     YTYTSGMWGVAVSAFIQLAICIVFLPIVAYISLKLVGDNPLLMLQSMVKEPFFPGNKS
                     ISDFMYTVLPLVLGSIFSYESFLRYQCADNAKNAVKSSVIAGFILLFLAFPIGIIGAI
                     GGSLFPNISSVQVLPQMISTTLPPLISVLFLAAILAAIMSTADSLMTSMSAIISRDIY
                     NKLLHPNIEFNDLKNTLKYSQIASALTAIIGAIIALKFDSLLELLFWPAPLCTGVIFA
                     PFVIGLCWKGATKKGAIYAVIVSVILALLNMIGILTVFDRILVPIIGGSITIFIVSKF
                     SKKD"
BASE COUNT         2180 a          746 c          886 g         1989 t
ORIGIN      
        1 taattcttaa agaaaggatt tttaataatg gatataaaag agttagttaa aatgcaaaga
       61 aaatattata atacaggtaa aacaagagat atatcgtttc gtatagaaca gttgaagaaa
      121 cttaagttag ttgtatcaca aaatgaagaa aaaatacttt tagcactaaa gaaagattta
      181 aataaatcgg attttgaagg ttttatgaca gaagtaggca tgttttatag tgaattaaac
      241 tttgctataa agaatataag aaaatggagc aaaataaaaa gagttaaatc aagtatggtt
      301 aattttccat ctatatccaa agttgttcca caaccttatg gtgttactct cataatgtca
      361 ccttggaatt atccatttca attagcactt ataccattag tttggtcatt agcagcaggg
      421 aattgtgtta tattaaaacc ttctgaatat tctgtgtcaa catctagtgt agttaaagac
      481 atagtggaag atactttttc aaaagaatat gttgcagttg ttcaaggaag tcaagaagaa
      541 agtgaaaagt tactattgga aagatttgat tatatatttt ttacaggaag tactaatgtt
      601 ggtaaaataa tcatgaaatc agcatcagag catttaactc ctattacttt agaacttgga
      661 ggaaaaagtc cttgtatcat tttaaaagat gctaatatag accttactgc caaaagactt
      721 acttggggaa aactaataaa tgcaggacaa acctgcgtgg ctccagatta tgttttagtg
      781 catgaagata gaaaaaatga gttaatagag aaaataaaat attatactaa taagtatttt
      841 ggagataatc catgtaataa tgagcaattt cctaaaatca taaatcagag acattttaat
      901 cgaatattat ctcttattga taaagataag atagtctatg gtggaaatta taataaggag
      961 acattaaaga tagagccaac tatagtagac aatgttaatt gggatgataa tataatgaag
     1021 gaagaaatat ttgggcctat atttcccatt ttaacatata aagatttgga tgaagtaata
     1081 caaaaaatta tacaaatgcc aaatccattg gcactttata tttttacaaa aaataagtac
     1141 ctagaaaata aacttttaga aatgatttca gcaggaggat gttgtatcaa tgatacagtt
     1201 actcatatag ctacgaatta cttacctttt ggtggtattg gtgaaagtgg tatgggctca
     1261 tatcatggaa aagctggatt cgatacattt actcactata agagtgtgtt aaaaaaatta
     1321 aatttggatg tccctattag atatgctcca tacgataata aattaattaa ggttcttaaa
     1381 aagataatgt aggttatatt gtagaataat aaatataaat aaaattgagt atttgtattc
     1441 tgaatatatt ttatttttaa tttggtatat ttgttataaa agtggtgatt ttgtgataaa
     1501 atttaattat atagaaataa ggaggaaaaa atgaaaatta attggaatac aaaatacaca
     1561 acaatagcaa tttatacatt tataatagct gctagtagta ttatatttta tctagtatca
     1621 tcacaaattg atgtattttc taataattta gatgctatat ttacaacatt acaacctttt
     1681 ataataggat ttgctattgc atatcttctt aattttattt taaagtttta tgaagacaga
     1741 atttttataa aaagtgagaa attaaaaaaa ctaaaacaaa gttcaaaaag aggcttgggt
     1801 cttttattaa catatgcaac agctacattg atactttact tatttatgca tttcgtattg
     1861 ccacaagtaa ttgagagtat tgttggacta gcaaatgata tacctatgta tgtaaacaat
     1921 gcaactaagc ttattgataa attaatgact gatttaaatc ttgatgagca atactttaat
     1981 ttagcagttg ataagtggaa tgagtttgtt acatatatta taaagtttgt aacagattta
     2041 atcccaatat taggaagtat gttaaagaat gtagcctcta gtatatggaa tattgtacta
     2101 ggattaattg tttcagtata cttattaatt gataaagaaa aattctatgg attaagcaaa
     2161 aaaataactt atgcagtatt tacagaaaaa caagctgcta gaattttaga attaactcat
     2221 agaagtaact atacatttgg aagattttta ggtggcaaaa tattagattc attcattata
     2281 ggtattctaa catttgtaat acttacatta gttaaaatgc catatacatt attaatatca
     2341 gttataattg gtattacaaa tattatccct ttctttggac ctttatttgg agctatacca
     2401 tccacgctaa tagtgatgtt tgtatctcct ataaaagctt tctggttatt gttaattata
     2461 ttaataatac aacagataga tggaaacatt ataggaccta aaatacttgg agattcaatt
     2521 ggtatatctg cattttggat tttgttctcc ttattggttg caggaaaatt attaggtttt
     2581 attggaatgg ttataggagt tccaatgttt gcagtaattt attctataat taaggatatt
     2641 gttgaaagta aattggacaa aaagggatta ccgacagata cttccgatta tatgtagcta
     2701 aaaaatatta tgtataatta aaaatatata aattaagcaa tatttaaagc actgagaaag
     2761 ttaaactctt ggtgcttttt agatataaaa ttattataga agaggtgttt tttgtggcat
     2821 ttatagaatg taaatttaaa tctaaatata ctggaggaga aactgatata attgtaattt
     2881 tgcctgtagc aaatggaaaa gaacttttta gtggtaaaga gatatatgat tttgaaggta
     2941 aatttaaaac attatactta tttcatggtt tagaagatga ccaaagctca tggattagat
     3001 atactaatgt agagcattat gctaaaaata aaaatatagc cctagtaata ccaagagtag
     3061 aaactagttt ttataccgat atggcgtatg gacaccaata ttttactttt gtaagcgagg
     3121 aattacctaa atttgttaga gctatatttc ctttatcaga taaaagggaa gataactttg
     3181 tagctggtat gtctatgggg ggatatggag ctttaaaatt agcgctttca aaaccaaaag
     3241 agttttcggc agttgcaagt ttttctggtt cgcctgatat gattcatgag ttagaaaatc
     3301 aacaaataga aaccaatgca gacattctat ttcacgattt tggtagacca gaagacgcta
     3361 gaaatagtga gaatgattta ctttacatac ttaagaacct taaagaaaga aatgaagata
     3421 ttcctaaaat ttatcaattt tgtggtgata gagatttttt atataaaaat aatcagatgt
     3481 ttaaaaaata tgcagattct ctgggtgtag atgttgaata tgaagagtgt gtaggggggc
     3541 atgaatggcg tctttggaat ttatggataa agaaatttat agatataatt ggatagtaca
     3601 cttatggtat taacaggtat actataaaat atctttaaat atgataaaga ctgaaatcct
     3661 aaaatcaaat tatgatttta aaatttcagt ctctaagaat ttaataaaat tttattaagt
     3721 tcttacacga gttattattg gagtaaaatt gtcaactata tctatatagt atttactcaa
     3781 ttcctctaaa atctcttcgc ataaatccgt actatgacca agattaataa gaaactgttt
     3841 tgtaaaatgc tttattacag cttgagaaga tatatcgtac ttgtgtgaag tataaactct
     3901 aattatttca ggtttcatag caagtatacc aatacaagaa agtattaatt catcatgttc
     3961 tatagattct ttatcattaa catatctttt catgaccatt tcggttacac ttctttgata
     4021 gcttaaaata gcttcttcat aagctatatc caaataaaaa tttctatatg cttcgttttt
     4081 tagaaggaaa caaaggtcag cattcatagc aagaaagaac atcatcatag taccttcttc
     4141 atggtagtta tagattaaag actgcatttc atttcttata tcttcatata ttatagctcc
     4201 tatttcgctt ttacttgaga agtaatagct tattagacct aaatttatat tagctctttc
     4261 tgcaatttgc ctagttgttg tcttatgata accttgctca aaaaataatt ctctagcagc
     4321 acttataata ctagcttttg tttctttgcc cttttctgat tttgacatat ttactgtgta
     4381 tacctctctt ttcaatcttt ttttgaaaat ttgctaacta taaatattgt aatagaacca
     4441 cctattatag gaactaaaat tctgtcaaat acagtaagaa taccaatcat atttaataat
     4501 gccaatataa cacttactat aacagcatag atagctcctt tttttgtagc acctttccag
     4561 caaagaccaa ttacaaatgg tgcaaatatt acacctgtac ataatggagc tggccaaaac
     4621 aataattcta ataaactatc aaatttaagt gctatgattg cacctattat agctgtcaaa
     4681 gctgatgcaa tttgagaata ctttagagta ttttttaaat cattaaattc tatattagga
     4741 tgtaataatt tgttataaat atctcttgat ataatagcac tcattgaggt cattaatgaa
     4801 tcggcagtag acattatggc agccaatata gcagctaaga ataatacaga tattaaaggt
     4861 ggcaaagtag tcgatatcat ttgaggtaaa acctgaacag atgatatatt tggaaataaa
     4921 ctaccaccaa tagctccaat tattcctata gggaaagcaa gaaataatag tataaatcct
     4981 gcaattacac tacttttaac tgcattttta gcattatcag cacattgata tcttaaaaaa
     5041 ctttcataag aaaatattga gcctaaaact aatggtaaaa ctgtatacat aaaatcacta
     5101 atcgatttat ttcctggaaa gaatggttct tttaccattg attgtaacat aagtaaaggg
     5161 ttgtcgccaa ctaattttaa gcttatataa gctactattg gcaaaaacac tatacaaata
     5221 gcaagttgaa taaatgctga tactgcaact ccccacattc ctgatgtata ggtatatata
     5281 attataacta taactcctat aattacagct atatcataag gaataccaaa tgcagtagat
     5341 acagaaccaa aagaaattaa ttgactaccc ataatagcta gtatggatat tggtgttaca
     5401 agactttgat aagctcttaa aaatacacta tgaccatatc tagtttcaat ataatcagca
     5461 ggtgttatat cacaagataa gcttcttaat tttcctgcga aaaatgcatt tataaagcaa
     5521 gctaaagctg cacctatagt agaatacatt ccaacccaaa gtcctctttc agctccccat
     5581 tgaactccac caactaagca ccctcctcca aaagatgtag cagcaatggt tgcagctagt
     5641 ataggcaaag gcagatttct acctgcgatt aggaaatcgg atgctgtttt aacttttttt
     5701 gaaaaataaa aaccaatcca tatgtatatt gcacacgtaa caattaaaag taacatagtc
     5761 ttttctcctt tataaaatat tttaataaaa tatacaaaat a
//
LOCUS       DAMKNB010000144         5775 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.150, whole genome shotgun sequence.
ACCESSION   DAMKNB010000144 DAMKNB010000000
VERSION     DAMKNB010000144.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5775)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5775)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5775
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.150"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            complement(179..2515)
                     /locus_tag="PC494_003492"
     CDS             complement(179..2515)
                     /locus_tag="PC494_003492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HDF3913945.1"
                     /translation="MKKNTLLHTNIMVCIIITLGFVATSIIGYQSNTNIFKNDIEHVS
                     TLAAEGIYYQIDKLLSEPINVSLTMANDSLLKNFLDGEKEHLNDEEFIYKLQDYLNVY
                     RNKYSYDSVFLVSTKTNNYYHFNGLDRNLSANNSENQWYYTFLKNDDEYSLNVDNDEA
                     SNNSITVFVNCKIKDDNGATMGIIGVGLKVNSLQMLLKGYNDKFDVVARLIDDKGFVQ
                     LAVDKTGHENINFFENSSSDLSNSKQLILNNKKEQKSFWYSSEKSKSYIVCQYIPSLK
                     WHLVLENDFTLMIKQLHLQFFKGIAVIVLIIIFVLFTITHVLKKYKNQIIKLSVSQKL
                     EYQKLLSKSTEGLYENIFEIDITNNKAGCEDENRYFHEFGLGLNTPYDEALHTIAKNQ
                     IKEEYAQGYLDTFLPENVIKRYNSGINNISYDFLIKKDEESYHWIRINARIFFWTSDE
                     SVRMISYRKNIDEEKNRELLLLERSQRDSLTGLYNKATTEEFIRSFLKNESNQDLEHV
                     FLIFDIDNFKNVNDKYGHVFGDFVISEFALELKSQFREDDIVGRIGGDEFVVLIKDFN
                     NNNYVLIDKLERFCSKINQKKFVEQAEFSIACSIGVAMYPEHGYVYSELYEKADQALY
                     YAKSHGKNSYHIFSEDSIDSISFHIDSRDIKVLLEMATDGVVKFACMENLKLLYFNQK
                     MLEFTGYSAQTVTSIGFDIFSPVLQDDLQMVLDTLREAISKRETFEIVFRFCHTDGHI
                     FPVRMQGKFVSELYQNRYPVFYAIYTDISSINTLLENK"
     gene            complement(2829..4370)
                     /gene="rny"
                     /locus_tag="PC494_003493"
     CDS             complement(2829..4370)
                     /gene="rny"
                     /locus_tag="PC494_003493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HDF3913946.1"
                     /translation="MDVIDSVVMIVIGAAVGIIAGYFVRKNISEAKIGQAENLAKEII
                     DKAHHDSETVQKEKLLEAKEEIHKWRTEAERENRERRTEVQKYEKRVVQKEEVLDRKL
                     QNLESKEVNLSEKLKVVEKKEEEVEVIKTQQLEKLESISGITSDKAKEIILTNAERDV
                     RREMSIMIKEIESQAKEEADKKSREIIGYAIQKCAADHVAETTVTVVSLPNDEMKGRI
                     IGREGRNIRTLETLTGIDLIIDDTPEAVILSGFDPIRREIARIALEKLIADGRIHPAR
                     IEEMVEKARKEVDNIIKEYGEQAAFETSVHGIHPELIRLLGRLNYRTSYGQNVLKHSI
                     EVAHIAGIMAAEIGADIRLAKRAGLLHDIGKAVDHEMEGTHVEIGMDLLRRYKESKEV
                     IHAMSTHHGDYEPQTVEAVLVTAADAISAARPGARRETLEAYIKRLEKLEEIANSYEG
                     VEKSFAIQAGREIRIMVKPEAINDEEIHLLARDMTKKIEDELEYPGQIKVSIIRETRA
                     IEYAK"
     gene            complement(4546..5592)
                     /gene="recA"
                     /locus_tag="PC494_003494"
     CDS             complement(4546..5592)
                     /gene="recA"
                     /locus_tag="PC494_003494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HDF3913947.1"
                     /translation="MSVDQEKLKALNEALGKIEKDFGKGSVMKLGEATSMSIDVISTG
                     AIGLDIAIGIGGLPRGRIVEVYGPESSGKTTVALSCVASAQKDGGIAAFIDAEHALDP
                     VYAKALGVDVDNLIISQPDTGEQALEIAEALIRSGAIDIIVIDSVAALVPKAEIDGDM
                     GDSHVGLQARLMSQALRKLTGSIKKSNCVAIFINQLREKVGIMFGNPETTTGGRALKF
                     YSSVRLDVRKIDTIKQGDKVIGSRTRVKVVKNKVAPPFKQAEFDIMYGEGISKIGDLL
                     DIAADVDIVKKSGSWYSYNDTKLGQGRENVKKFLEDNLDLTTEIDEKVRAFYNLNEEH
                     EESGTSVSKEIVEE"
BASE COUNT         1796 a         1052 c          613 g         2314 t
ORIGIN      
        1 tgcttaaaat aataagtaaa gtcttaaaaa aaataaatct tgttagccaa aaataagatt
       61 tattataaaa aatttaaaaa cctgctaaaa ataatctatt ttcattagca ggttttattt
      121 ataatcttct tatattaata ctattatatc ctatttttag attttactgt agtatttact
      181 atttattttc tagtaaagta ttgatacttg atatgtctgt ataaatcgca taaaaaacag
      241 gataacgatt ttgatataat tcacttacaa acttaccttg catccttaca ggaaaaatat
      301 gaccatctgt atgacaaaaa cgaaaaacta tttcaaaagt ctctctttta gaaattgctt
      361 ctcttaatgt atctagtacc atttgtaagt cgtcttgtaa tacaggcgaa aaaatatcaa
      421 aacctataga agtaacagtt tgagctgaat atccagtaaa ttcaagcatt ttttggttga
      481 aataaagtaa ttttaagttt tccatacaag caaatttgac aacaccatca gtagccattt
      541 ctaataatac ttttatatct ctagagtcta tatgaaatga aatactatca atagaatcct
      601 ctgaaaatat atgataagaa tttttcccat ggctttttgc atagtaaagt gcttggtctg
      661 ctttctcata tagttcagag tatacatatc catgttcagg atacattgct acaccaatac
      721 tacatgcaat agaaaattct gcttgctcaa caaatttttt ctgattaatc ttagaacaaa
      781 aacgctctaa tttgtctata agcacatagt tattattatt aaagtctttt attaatacta
      841 caaactcatc tccaccaata cgtcccacaa tatcgtcctc acgaaattga gattttaatt
      901 ctaaggcaaa ttcacttata acaaagtctc caaatacatg accatattta tcatttacat
      961 ttttaaaatt atcaatatcg aaaattagaa aaacgtgttc taaatcttga ttactttcat
     1021 tttttaaaaa tgaacgaata aattcctctg ttgtagcttt attgtaaagc cctgtaagag
     1081 aatcacgttg tgaacgttcg agaagtagta attctctatt tttttcttca tctatatttt
     1141 tacgataaga tatcatacga acagattcat ctgatgtcca aaagaaaatt cgtgcattaa
     1201 ttctaatcca atgataactt tcttcatctt ttttaattaa aaaatcatag ctgatattat
     1261 taattccgct attataacgt ttaattacat tttcaggtaa aaatgtatct aaataacctt
     1321 gtgcatattc ttctttgatt tggtttttag ctattgtatg taaggcttca tcatatgggg
     1381 tattaagccc taatccaaat tcatgaaaat acctattctc atcttcacaa ccagctttat
     1441 tgttagtaat atcaatttca aaaatatttt cataaagacc ttcagtagat ttgctcaaca
     1501 atttttgata ttccaatttc tgtgaaacac taagctttat tatttggttt ttgtattttt
     1561 taagcacatg tgtaatagta aaaagtacaa atattataat taaaactata actgcaatgc
     1621 ctttaaaaaa ttgcagatga agctgtttaa tcattaaagt aaaatcattt tctagaacaa
     1681 gatgccattt taaactaggt atgtactgac atacaatata actttttgat ttttcagatg
     1741 aataccaaaa actcttttgt tcctttttgt tgtttaatat taattgtttc gaattagaca
     1801 agtcgctact agaattttca aaaaaattta tattctcatg accggtttta tctactgcta
     1861 attgtacaaa ccctttatca tcaattaagc gtgcaacaac atcaaatttg tcattatatc
     1921 ctttaagcaa catttgtaat gaattaacct ttaacccaac acctataatt cccatagttg
     1981 ctccattatc atcttttatc ttacaattta caaagactgt aatactattg ttacttgctt
     2041 catcattatc aacatttaat gagtattcat catcattctt taagaaagta taataccatt
     2101 gattctctga gttattagcg ctaagatttc tatcaagtcc attaaaatga taataattat
     2161 tggttttagt tgatactaaa aaaacagaat catatgaata tttatttcta tacacattca
     2221 gataatcttg taatttataa ataaattctt catcatttaa atgttctttc tcaccatcta
     2281 aaaaattttt taatagactg tcatttgcca ttgtaagaga tacatttata ggttctgaaa
     2341 gtagtttatc tatctgataa taaatacctt cagcagccaa tgtagataca tgttcaatat
     2401 catttttaaa aatattggta ttagattgat atccaattat agaggtagcc acaaaaccaa
     2461 gagtaataat aatgcaaacc ataatatttg tatgtaaaag tgtatttttt ttcatagtgt
     2521 accctctctc taatcctcac tttagcgtca ttgtattttc atcttattta agtacaagca
     2581 ttccaagtag taatatattt attttacaac ttcattatat caaacaaact tggataatta
     2641 tataaataat acatatataa agctttattt tattaatctt ttgtaagtag cacttttagc
     2701 acttagatta tttttgcatt atataaaatt aaacttaaac aatttaaaag ccacaagata
     2761 tattatcata tcttgtggca aatttaaatt tctaaaaata ttttcttatt atttagatat
     2821 tatttctttt acttcgcata ctctatagct cttgtttctc ttattatgct tacttttatt
     2881 tgtccaggat attcaagttc atcctctatt ttcttagtca tatctctagc caatagatgt
     2941 atttcttcat catttatagc ttctggtttt accattattc ttatttctct accagcttgt
     3001 atagcaaatg atttttctac accttcatat gaattagcta tttcttctaa tttttcaagt
     3061 ctctttatat atgcttctaa agtttctctt ctcgcaccag gtctagcagc tgatattgca
     3121 tctgctgctg taactaatac agcctctact gtttgaggct cgtaatctcc atgatgagta
     3181 ctcatggcat gtataacttc tttagactct ttataacgtc taagtaaatc catacctatt
     3241 tcaacatgtg taccttccat ttcatggtct acagccttac ctatatcatg taataaacct
     3301 gccctcttag ccaatctaat atctgctcct atttcagcag ccattatacc agctatatga
     3361 gcaacttcta tagaatgttt aagtacattt tgtccataac tagttctata gttaagtcta
     3421 cctaataatc ttattaattc cggatgaatc ccatgtacac tagtttcaaa tgcagcttgt
     3481 tcaccatatt cttttataat attgtcaact tcttttctcg ccttttcaac catttcttca
     3541 attctagctg gatgtattct tccatctgct attaattttt ctagagcaat tcttgcaatt
     3601 tctcttctta ttggatcaaa tcctgataaa attacggctt ctggagtgtc atctattata
     3661 aggtctatac ctgttaaggt ttctaaagtc cttatatttc taccttccct acctattatt
     3721 ctacctttca tttcatcatt aggcaagctt actactgtta cagtagtttc ggctacgtga
     3781 tctgctgcac atttttgaat tgcatatcct ataatttctc ttgatttctt atcagcttct
     3841 tctttagctt gactttctat ctcttttatc attatagaca tttcacgtct tacatctctc
     3901 tccgcattgg ttaagatgat ttctttggcc ttatcagaag taattcctga tatactttct
     3961 aatttttcta actgttgagt ttttattact tcaacttctt cttctttctt ttccactacc
     4021 tttaattttt cacttaggtt tacttcttta gattctaaat tttgtaattt tctatctaag
     4081 acttcttctt tttgtactac tcttttttca tacttttgta cttctgttct tctttctctg
     4141 ttttctcttt cagcttctgt tctccactta tggatctctt ctttagcttc tagtaatttt
     4201 tctttttgta ctgtttctga gtcgtggtgt gctttatcta ttatttcttt ggccaagttt
     4261 tcagcttgtc caatttttgc ttcagatata ttttttctaa caaaatatcc agctataata
     4321 ccaacagctg cacctattac aatcattact acactatcta tgacatccac ctccttcgtt
     4381 aataatccca aaatgtcatc actatgatta aaaaatattc ctaataatta aaattaaatt
     4441 tagatatttt atcctcactt aattttataa ttttttcaac attgtgtcaa gctaataggg
     4501 agcgtggcat gtctttaatt actagttatt tttttgtatt tttacttatt cttctacaat
     4561 ttcttttgat actgaagtac ctgattcttc atgttcttca tttaaattgt aaaatgctct
     4621 aactttctca tctatttcag tagttaaatc taaattatct tccaagaatt ttttaacatt
     4681 ttctcttcct tgtccaagtt tagtatcatt gtaactatac catgaacctg attttttaac
     4741 tatatctaca tcagcagcta tatctaaaag gtctccaatt tttgaaatcc cttctccata
     4801 cattatatca aattcagctt gcttaaatgg tggtgctact ttgtttttaa caactttaac
     4861 tctagttcta ctacctataa ctttatcacc ttgttttatt gtatctattt ttctaacatc
     4921 caatctaact gatgaataga attttagtgc acgtcctcca gtagtagttt ctgggtttcc
     4981 aaacattatt cctactttct ctcttaactg gtttataaat atagcaacac aatttgattt
     5041 tttaattgaa ccagttaact ttctaagtgc ttgtgacata agtctagctt gtaaacctac
     5101 atgagaatca cccatatctc catctatttc agcctttgga actaatgctg ctactgagtc
     5161 tattactatt atatctatcg ctccacttct tatcaatgcc tctgctatct ctaaagcctg
     5221 ttcacctgta tctggttgag atattattag gttatcaaca tccacaccca aagcttttgc
     5281 atatactggg tcaagtgcat gttctgcatc tataaatgca gctattcctc catctttttg
     5341 agctgatgct acacaactaa gcgcaacagt agtcttacca gaagattctg gaccatatac
     5401 ttcaactatt ctccctctag gtagacctcc tataccaata gctatgtcta aaccaatcgc
     5461 tcctgttgat ataacatcta tagacataga tgttgcttct cccaatttca ttactgaacc
     5521 tttaccaaaa tctttttcaa ttttacctaa agcttcattc aacgctttta atttttcttg
     5581 atctacactc atctctatac catcccttca tttatctaca aacatttgtt ctcttgttat
     5641 atattaatta tataacataa atcaaaccta gtcaatttaa aaacgctact aatgattata
     5701 tttttattca ttacatttta tttataaacc attattaata attatataca caaaagaaaa
     5761 tattcttaaa atgaa
//
LOCUS       DAMKNB010000145         5762 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.151, whole genome shotgun sequence.
ACCESSION   DAMKNB010000145 DAMKNB010000000
VERSION     DAMKNB010000145.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5762)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5762)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5762
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.151"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            87..1199
                     /locus_tag="PC494_003495"
     CDS             87..1199
                     /locus_tag="PC494_003495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HDF3913948.1"
                     /translation="MNAFIRKRNKNYVVYLEFEDEKTGKRKQKNMGTFDKKREASKRL
                     NEVKESLYNDGFLVPSEITVSEFLLDFLNKYSENISLATYNNYVSICKNYINPSIGKY
                     KIQDLHPVHIQNYIDKLSYKLNPQSIKIHINILKLAIKRAYRLKLIKENVMDSIEAPR
                     YKKFKNEIYDREQMIKLLDLAKNTEMELPINLAIGLGLRISEVLGLTWDNIDFEENTI
                     TVNKITSRINGSVILKEPKTESSVRKISSPKELMSLLKEYKIKQNKNLLKSSIRNNNN
                     LLFFNKKCEPIAEDVMSKKFKRFLEKNELPHIRFHDLRHSHVTLLINSKVPIKVISER
                     VGHSNISTTLSVYSHVLKEMDKEASDKISESLFNAN"
     gene            complement(1407..1883)
                     /locus_tag="PC494_003496"
     CDS             complement(1407..1883)
                     /locus_tag="PC494_003496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3913949.1"
                     /translation="MVKKRLVAVVISLAMISVGNFSYAHSGGHNSSGGHHNKNKSELT
                     RYYCGGHSAHQHNKGFCPYASTKENSGVTISSVHNEKNHKNYFAEKGYNKGYEDGCKG
                     LYNLSVTEAKSDNLYEKEILKSSYEKGYLIGYNEYKAKKVDDVMKKMLDIPMLASI"
     gene            complement(2082..3707)
                     /locus_tag="PC494_003497"
     CDS             complement(2082..3707)
                     /locus_tag="PC494_003497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDF3913950.1"
                     /translation="MLQVTGVGLRFGDKELFKDVNLKFTKGNCYGIIGANGAGKSTFL
                     KILSGEIEPNTGSISITDKERMSVLKQDHFEYEEETVLNVVIRGHERLWNIMKEKDAL
                     YMKEDFNEEDGIKAAELEGEFAELDGWDAETNAEKILMGLGITKDMHYKQMKELVGGE
                     KVKVLLAQSLFGKPEILLMDEPTNHLDFKSINWLNNFIMDLEESIVIIVSHDRHFLNQ
                     ICTNIVDVDFGKIQMYVGNYDFWYESSQLALQLAKDQNKKTEEKIAQLKEFIARFSSN
                     ASKAKQATSRKKQLEKLEVEDIQPSRRRYPYVGFTPAREIGNEVLEVHNLTKTIDGVK
                     VLDNVSFRLDRDDKVVFMGDEIATTALFNIVMGELEPDSGEYKWGVTTSQDYLPKNHN
                     KFFDGVEYSLVDWLRQFSEEKSESFIRGFLGRMLFSGEEALKEAQVISGGEKVRCMLS
                     KLMLSNANVLVLDDPTNHLDLESITSVNKGLEKFPGVLLFTSHDHEFISTIANRIIEI
                     TPNGIMDRKMDFDEYLESKEIQDQLAKMYGKDK"
     gene            complement(4045..5064)
                     /locus_tag="PC494_003498"
     CDS             complement(4045..5064)
                     /locus_tag="PC494_003498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-binding protein"
                     /protein_id="HDF3913951.1"
                     /translation="MKLIKTIDAVGQVLCHDITQIIPGEFKGRKFKKGHIVKEEDIPV
                     LLSLGKDNLYVWEKSEGMVHENEGALFLKELTAGENLDFSEIKEGKIDFIAACDGLLK
                     IDVDALFDLNCVGEIMMATLHNNFIVNKGLKVAGTRVIPLVIDEKKLEDAKKVVGNRK
                     IVNVVPFKPKKVGIVTTGNEVFYSRIVDKFGPVIEEKVKGFGCEVIGQTICPDDKEII
                     KSAIKEFISQGAELICCTGGMSVDPDDVTPTAIKETGADLVTYGSPILPGAMFLLAYY
                     GEVPIMGIPGCAMYHKTTVFDIVLSRVLIDEKLDKYDIARYGHGGLCMNCDVCTYPAC
                     NFAKI"
     gene            complement(5061..5630)
                     /gene="mocA"
                     /locus_tag="PC494_003499"
     CDS             complement(5061..5630)
                     /gene="mocA"
                     /locus_tag="PC494_003499"
                     /EC_number="2.7.7.76"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdenum cofactor cytidylyltransferase"
                     /protein_id="HDF3913952.1"
                     /translation="MINAVIMASGFARRMGANKLLLNYKGCSIIEHVFREVSKIDFHQ
                     VVVVSQYEEVLLLCNKYGFEYIDNKNANIGQSESIKLGVLNSSKCDGYMFFVGDQPFI
                     DNLYIDKIINTFKLDRDFIVIPRYKDMCGNPVIFPYSKKEELLALKEDEKGKTILKNS
                     SKIKYVEVPKEMLFDIDTKMDYERIGGKL"
BASE COUNT         1963 a          973 c          595 g         2231 t
ORIGIN      
        1 aaaatgtatg caactctatt tcaaaattat tttgtgatat atatatgtta taataaatgt
       61 ataaaatttt gattggtggg ttatatatga atgcatttat tagaaaaaga aataaaaact
      121 atgttgttta cctggaattt gaagatgaaa agacaggtaa aagaaaacaa aaaaatatgg
      181 gtacttttga taaaaaaagg gaagcaagta aaagactaaa tgaggtaaaa gaaagcttat
      241 ataatgatgg ttttttagta ccaagcgaaa ttacagtgtc agaatttcta ttagattttc
      301 taaataaata tagtgaaaat atatctttag ctacatataa taattatgtt agtatttgta
      361 agaattacat taatccatct attggaaaat ataaaataca agacttacat ccggttcaca
      421 tacaaaacta catagataaa ctatcttata aactaaatcc tcaatcaatt aagattcata
      481 taaatatatt gaaacttgca ataaaaagag cttatagact caaattaata aaagaaaatg
      541 ttatggatag tatagaggct ccaagatata aaaaatttaa aaatgagatt tatgatagag
      601 aacaaatgat aaaattatta gatttagcaa aaaatacaga aatggaatta cctattaatt
      661 tggctattgg attaggtctt agaatttcag aagttttagg tctaacttgg gataatattg
      721 attttgaaga aaatacaata acagtaaata agataacttc ccgaattaat ggttctgtta
      781 ttctcaaaga gccaaagaca gaaagctctg ttagaaaaat atcttctccc aaagaattaa
      841 tgtctttatt aaaagaatat aaaataaaac agaataaaaa tttattaaaa tcttccatta
      901 gaaataataa taatttgttg tttttcaata agaaatgtga acctattgct gaagatgtta
      961 tgagtaaaaa atttaaaaga tttttagaaa agaatgaatt acctcatatt agattccatg
     1021 atttaagaca ctcacatgtt actttactta taaattctaa agtacctata aaggttatat
     1081 ccgagagagt aggacactca aatataagta ctactctaag cgtttattct catgtactta
     1141 aagaaatgga taaagaggct tctgacaaaa tttctgaaag tttatttaat gctaattaat
     1201 attaatttat cttagcttta aattagctta gcttattgag atagattcat taatattaaa
     1261 tgtatctatc tcaaattaat aactacttaa ataatctgtt ttattttaat ttatcgcctc
     1321 agttattata cttttttacg aaaaattata ctttacaata aaaaagatat tcccttatag
     1381 aaaatatctt tttaaatact atattattat atacttgcta acattggaat atctaacatc
     1441 ttcttcatta catcatctac tttttttgct ttatattcat tgtatccaat taaatatcct
     1501 ttttcatatg aactttttaa aatctctttt tcatataaat tatcagattt ggcttctgtg
     1561 acacttaaat tataaagccc tttacaccca tcttcataac ctttattata ccctttttct
     1621 gcaaaatagt ttttatgatt tttttcgtta tgtactgaag atattgttac tccagaattt
     1681 tcttttgtac tagcataagg acaaaaacct ttattgtgtt gatgtgctga atgtcctcca
     1741 caataataac gtgttaactc tgatttattt ttattatgat gacctcctga tgaattatgc
     1801 cctcctgagt gagcatatga aaaattccct acactaatca tagctaaact aattactaca
     1861 gctactaacc ttttcttaac cataatctat tccccccaaa atgttatata tttttattat
     1921 atcatctact atattatatt taaattctta atatacaaaa tattactcta ttctgctaat
     1981 aaacatgttt aaacaacata aaaaacctcc taatatttga ttaaaaattt acacactcat
     2041 gcatagcatg tctcaaatat taaaaggttt tatactaata attatttatc ttttccatac
     2101 attttagcta attggtcttg tatctcttta ctttctaaat actcatcaaa gtccattttt
     2161 ctatccatta ttccatttgg agttatctct ataattctat ttgctatagt agatataaat
     2221 tcatggtcat gagaagtaaa taaaagcact cctgggaact tttcaagtcc tttatttaca
     2281 gaagttatac tttctaggtc taagtggtta gtagggtcat ctaatacaag tacatttgca
     2341 tttgaaagca ttagcttact aagcatacat ctaacctttt ctcctccaga tataacttga
     2401 gcttctttta atgcttcttc acctgagaat aacattctac ctaaaaatcc tcttataaaa
     2461 ctttcacttt tttcttcaga gaactgtcta agccagtcaa ccaaagaata ttctactccg
     2521 tcaaaaaact tattatgatt ttttggaaga taatcttgag aagtagttac tccccattta
     2581 tactctccac tgtctggttc aagttctccc ataactatgt tgaaaagtgc agtagtagct
     2641 atttcatctc ccataaatac tactttatca tctctatcca atctaaatga cacattatca
     2701 agaaccttaa ccccatctat agttttagtt aaattgtgta cttctaaaac ttcattccca
     2761 atttctcttg caggtgtaaa tcctacatat ggatatcttc ttcttgatgg ttgtatatct
     2821 tcaacttcta atttctctaa ctgtttcttt cttgatgttg cttgtttagc ctttgaagca
     2881 ttagaactaa atctagctat aaattccttt aattgagcta tcttttcttc agtcttttta
     2941 ttttggtcct tagccaattg taaagccaat tgacttgact cataccagaa atcatagttt
     3001 ccaacgtaca tttgtatttt accaaaatct acgtcaacta tattagtaca tatttgattt
     3061 aggaaatgtc tatcatgtga tactattata actatagatt cttctaaatc cattataaaa
     3121 ttatttaacc agtttattga tttaaaatct aagtggtttg taggttcgtc cattaatagt
     3181 atttcaggct taccaaaaag tgattgtgct aacaatacct taaccttttc cccaccaact
     3241 agttccttca tttgtttgta atgcatatct ttcgttatgc caaggcccat aagtattttc
     3301 tcagcattag tttctgcatc ccatccgtca agctctgcaa actcaccttc aagttcggca
     3361 gcttttatcc catcttcttc attaaagtct tccttcatat acaatgcatc tttttctttc
     3421 attatgttcc aaagtctctc atgacctctt ataacaacat ttaaaacagt ttcttcttca
     3481 tattcaaagt ggtcctgttt taaaactgac attctttctt tatcagttat agatatacta
     3541 cctgtattag gctctatttc tcctgataat atttttaaaa aagtagattt tcccgcacca
     3601 ttagctccta ttattccata gcaattacct ttagtgaatt ttaagttaac atctttaaat
     3661 agttccttat caccaaatct aagtccaaca cctgtaactt gtaacattaa tatattttcc
     3721 tttctttttg ctcataattt attttatcat aaaactttga taacattttt attatatatt
     3781 atcacgtaaa tagtatattt tttatactaa atttgtgaaa tatttattaa aataatacta
     3841 aaaattgtaa atttataaaa attaacaatc tcttatatta tacttataaa gaaatcaaat
     3901 tgcaacttta ttcattcttt tacacattga aaataagtta ttataatttc taaataaata
     3961 tgcttttctt aaaacatcat tctagctgtt ttgtttcata tttaaaaaga gtacttaatt
     4021 tgtaaatact cttttttaat aactttatat tttagcaaaa ttacatgcag gataagtaca
     4081 tacatcacag ttcatacaaa ggccaccatg accatatcta gctatatcat acttatcaag
     4141 cttttcatca attaaaaccc tagataaaac tatatcaaat actgtagttt tgtgatacat
     4201 tgcgcatcct ggtataccca taattggaac ttctccataa taagcaagta aaaacatagc
     4261 tcctggtaat attggtgaac catatgtcac taaatcagct ccagtttctt ttatagctgt
     4321 tggtgtaaca tcatctgggt ctacactcat cccaccagta caacagataa gttctgctcc
     4381 ttgacttata aattctttta ttgcactctt tataatctct ttatcatctg ggcatatagt
     4441 ctgtcctata acttcacaac caaagccttt tactttttct tctattacgg gtccaaattt
     4501 atcaacaatt ctgctataaa acacttcatt tcctgtagta acaattccta ctttcttagg
     4561 tttaaaaggt actacattta ctatttttct attaccaact actttttttg catcttctaa
     4621 ttttttctca tctataacca aaggtatcac tcttgttcca gctactttta aacctttatt
     4681 tactataaaa ttattatgaa gagtagccat cattatttct ccaacacaat tcaaatcaaa
     4741 aagtgcatca acatctatct ttaatagacc atcacatgct gctataaaat ctattttccc
     4801 ttcttttatt tcactaaaat ctaaattttc tccagcagtt agttctttta aaaacaatgc
     4861 gccttcattt tcatgaacca ttccttctga cttttcccat acatacaaat tatctttacc
     4921 aagagataat aacactggaa tatcttcttc ttttactatg tggccttttt taaattttct
     4981 tcctttaaat tctccaggta ttatttgagt tatgtcgtga cataaaactt gtccaacagc
     5041 atctatagtt tttattagct tcataattta cccccaattc tctcatagtc catttttgta
     5101 tcgatatcaa ataacatttc tttaggaact tctacatact ttatttttga tgaatttttt
     5161 aaaatggttt tacctttttc atcttcttta agtgccaaca attcttcttt cttgctatat
     5221 gggaatatga ctggatttcc acacatatct ttgtatcttg gaattactat aaaatctcta
     5281 tctaatttaa aagtatttat aattttatct atatataagt tatcaataaa tggctggtct
     5341 cctacaaaga acatataacc atcacatttt gagctattta aaactcctaa ttttatagat
     5401 tcactttgac ctatatttgc atttttatta tctatatatt caaaaccata tttattacac
     5461 aataacaaaa cctcttcata ttgacttact actacaactt gatgaaaatc aatcttgcta
     5521 acttctctaa atacatgttc tattatagaa cagcctttat aatttaataa aagtttattt
     5581 gctcccattc ttctggcaaa gcctgatgcc attatcactg catttatcat atatatcatc
     5641 cttggtattt ataatatatt gatagttcta tgatttttat aatatctcta ttgatattat
     5701 ctatatatat aatatcatat aaactatttt aatacttcaa tatcttacac aaaatttttg
     5761 tt
//
LOCUS       DAMKNB010000146         5679 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.152, whole genome shotgun sequence.
ACCESSION   DAMKNB010000146 DAMKNB010000000
VERSION     DAMKNB010000146.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5679)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5679)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5679
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.152"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            73..738
                     /locus_tag="PC494_003500"
     CDS             73..738
                     /locus_tag="PC494_003500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3913953.1"
                     /translation="MKGNIVQYNFADIEEEVYSLDYAIAWNTDEENVNIIPFTNKFCK
                     ESIESFCLGKINNFVEILNEGFVENHHYVHLDKMISVPKKKVNLVYQQDTHGYLLRDD
                     NDNLIPAKITSEQSKSISSKMELFSAGEEKCLINILLKADPSYILDVDSIKDKNILNL
                     GYESIDRYKEYNFDDDKILIFFINKKRYSVIMKKTNNSDNDLVSRNNAIKELFTNKAG
                     NLN"
     gene            complement(1244..3946)
                     /locus_tag="PC494_003501"
     CDS             complement(1244..3946)
                     /locus_tag="PC494_003501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HDF3913954.1"
                     /translation="MKNVSKKFFVCTIIVLITFLCFSKFAIYVFDKQEKKETKVVENM
                     LNVYKNNIILNLTEKFNYSKDLTSVLVSNNYSIDKLKPIADEILKNNSCIYISVVEKY
                     NVAAFFSNSVKKDIINTPIQELNYSYSLANSIKGLVVEGPSKDQFSNGDVFLITNPIY
                     KNGEYWGEITVALDAKKVVDSFNLNKLKESGFEYELWRVHLDNGSKSTIEISTKDFNF
                     SKSHEIKFKLPTVWTLSIVYKNGWNNKNIDFIVFVILLIISILIGVMTFIYIEKKSIS
                     KELNQQSLKNLETGILNREGFLIKLQEHLNRKNNEIVLLYICITNYSKFAPVMSFEKR
                     QDYLTHIVKNLDNYIKSSHFIARISEEGFVLALEENCDKNELLNIEKGISLELLRKIK
                     VENKQVFLTIGYGSSRCVDDRKDAESLLLSAIEDYERRFPAMSPIHDFTKKCEDMLDE
                     KKQIVFGEYPDLEINKLSKVIYKYYKKVQRIMYKDYNIDIGNRRGYMRDVEVLIDYNS
                     ERMLYLFLIDICKFGKFNELFSIEIGDVILKEVSNKLKTIFSNYLYRINGDVFLGISI
                     DKESYLDTLHKVNEVFNSSLSVEDVLFDIKCNIGICQYPYHGENPYDLLEKVQIALEY
                     AKKDVKSNVKVYDKELTEEIYHENNIIKDLKKGLEEQTLEVWYQPIFNVSKNCYIKAE
                     ALIRLRNKEGGYYSAYEVITYAEKHGLIKDVGLYVLKKACDVTTKIKDKNIDFEQMQL
                     NLSVQQIVHKQCANDILSCIENCGLDKKYICVEVTETVLMETFEIVNVTLDKLKKEGI
                     SIALDEFGSGFSSINYLANLPIENLKIDKELVEQITYSKKQFELLKTIVQIAKINGMD
                     IVAEGVETKETLDLVVTSGVNLIQGHYFSEPLSEDKFIELMIEE"
     gene            complement(3972..5522)
                     /locus_tag="PC494_003502"
     CDS             complement(3972..5522)
                     /locus_tag="PC494_003502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HDF3913955.1"
                     /translation="MRYKKRNIDKSSELSFQSLAKYFITFYIVIILIILSMFCINTIW
                     VMKKDNQDLLSTTSNRIEDRVGETIKLLNSLSKDNYIIDNSVNGIDKSKELSMYSDEF
                     GYMMICFVDKNIIVWDEEGGNISLAGRDYMQKLFATKKYQVTDSFAAGADGKTLNYTI
                     ASPIIKNGNVDGCVFAAIYFDEIKDILKQGKGQQQQNFILFGSENQIMNLTSDETAYG
                     EKYMKLSQKTKYLGTNAKKVEKDMFNNKSGDYWAFENGKLYFMSYKPIKNTNWSLFCK
                     VNFLDIFALNLIPMGAILSVITLVFIILICMEKSFMKKRMEVIDMLLGSVQELEKRIY
                     QTERPSEVDFKEIIQLTSKGLTDGLTGVVTRTVFFDQIYNRVEMEENDKLSVISFVDL
                     DDLKCINDLYGHEIGDMVLKNVGYVLREYEIKYNGLIGRYGGDEFVMLLSGFTSREEV
                     EDLLDEIAIRLHTEVLTDDGIIQTHCSVGAVVCSVKDNKDIDNLLKQADEALYYVKRN
                     GKGNYHLV"
BASE COUNT         2042 a          923 c          551 g         2163 t
ORIGIN      
        1 tgatattatt taaatataat ataagtttta taaagtatat taaatatatt ataagatgga
       61 ggtcgagtaa ttttgaaagg aaacatagta caatataatt ttgcagatat agaggaagaa
      121 gtatattcgt tggattatgc tatagcatgg aatacagacg aggaaaacgt aaacataata
      181 ccatttacaa ataaattctg taaagaatct atagaatctt tttgcctagg taaaattaat
      241 aactttgttg aaatattaaa tgaaggtttt gttgaaaatc atcattatgt acatttagat
      301 aaaatgatta gtgttcctaa gaaaaaggtt aatttagtat atcaacaaga cacacatggt
      361 tatcttctaa gagatgataa tgacaacctt attcctgcaa aaataacttc agagcaatct
      421 aaatctatat caagtaagat ggagttattc tctgctggtg aagaaaaatg tttaatcaat
      481 atattactaa aggctgaccc atcatatatt ttagatgtag atagtataaa agacaaaaac
      541 attctaaatc taggttatga gtctattgac agatataaag aatacaattt tgatgatgat
      601 aagattttaa tattttttat aaataaaaaa cgttattcag tgattatgaa aaaaacaaac
      661 aactctgata acgatttagt ttccagaaac aatgctatta aagaattatt tactaataaa
      721 gcaggaaatc ttaactaata atataatttt aaattatgtt attgattaaa ttaataatag
      781 tatacaaaga ggctgtctca aaatagagat aagcttcttt ttcattgttg aaataataaa
      841 atatatttaa ttctatataa aagagagtgc ctcataaact aaaaagttca ttttgagaca
      901 ccctcctatt tataataaac aaataaatcc ttaaacctat cgagtgatta taatttttag
      961 attgggttat cttgcatttt taaatttaag gtaactttct actctaaact ttaatctcta
     1021 atcaatatca tcaactgtaa caacttacaa ttaaatcttt aataatcaaa ctttagacta
     1081 tctatattaa aactcaaatt agatttagga tttatttgga tatcacattt attttattaa
     1141 ctactaatca attattttta cttataaact tattcttccc taattctatt attaaatact
     1201 tttaattatt tttcaatacc ttaaatcttt attttattaa cctttattct tcaatcataa
     1261 gttcaataaa tttatcttca cttaaaggtt ctgaaaaata atgaccttga atcaaattca
     1321 cacctgaagt tacaactaaa tccagagttt cttttgtttc aacaccttct gctacaatat
     1381 ccatgccatt aatcttagca atttgaacta tagtttttaa taattcaaat tgttttttag
     1441 aataggtaat ttgttctact aattccttat ctatttttaa attttcaata ggtaaatttg
     1501 ccagataatt tatactacta aatccagaac caaactcatc taaagctatg ctaatgcctt
     1561 ctttttttag tttatcaaga gtaacattta caatttcaaa agtttccata agtactgttt
     1621 ctgtaacttc aacacaaata tactttttat ctagaccaca attctcaata catgataata
     1681 tgtcatttgc acactgctta tgtacaatct gctgaacaga taaatttaat tgcatttgtt
     1741 caaaatctat atttttatct tttatttttg tagttacatc acaagccttt tttagtacat
     1801 atagacctac atccttaata agtccatgct tttctgcata agtaataact tcataggcag
     1861 aataataacc gccctcttta tttctcaatc taattagtgc ctcagctttt atataacagt
     1921 ttttactaac attaaaaatt ggctgatacc aaacttctag tgtttgttct tccagacctt
     1981 tttttaaatc cttaataata ttattttcat ggtaaatctc ttctgtcaat tccttatcat
     2041 aaactttaac attacttttg acatcctttt ttgcatactc caatgcaatt tgtacctttt
     2101 ccagaaggtc atatggattt tcaccatgat atggatattg acaaatacca atattacatt
     2161 ttatatcaaa aagtacatct tctacactta aagaactatt aaatacttca ttaaccttat
     2221 gtaaagtatc taagtaagat tctttatcta ttgaaatgcc taaaaataca tctccattaa
     2281 tacgatatag ataattagaa aaaattgttt ttaatttgtt actaacttct tttaaaataa
     2341 catctcctat ttcaatagaa aacagttcat taaattttcc aaacttgcat atgtctatta
     2401 aaaataagta taacattctc tcagaattat aatcaattaa tacttcgaca tcacgcatat
     2461 accctcgtct atttccaata tcaatattat aatctttata cataatacgc tgtacttttt
     2521 tataatattt gtatattact ttagacaact tgtttatttc taaatctgga tattcaccaa
     2581 atacaatctg tttcttttca tcaagcatat cttcacactt tttagtaaaa tcatgaatag
     2641 gagacattgc tggaaatctt ctctcataat cttcaatagc tgaaagtaac agagattctg
     2701 catcttttct atcatcaaca cacctagatg agccataacc aatcgttaaa aatacttgtt
     2761 tattttctac tttaattttt cgtaaaagct ctaaggaaat ccctttttca atgttaagca
     2821 attcattttt atcacaattt tcttctaaag ctagaacaaa accttcctca cttatacgag
     2881 caataaaatg agaacttttt atgtaattat ctagattttt tactatatgt gtaagataat
     2941 cttgtctttt ttcaaagctc ataactggag caaatttact ataattagta atacatatat
     3001 acagcaacac tatttcatta ttttttctat tcagatgctc ttgtaactta attaaaaaac
     3061 cttctctatt caaaatacca gtttctaaat ttttaagact ctgttgattt aattccttac
     3121 taatcgactt cttttcaatg taaataaatg tcatcacacc tattaatatg gaaataatta
     3181 acaatataac aaatacaata aaatctatat tcttattatt ccatccattt ttgtacacaa
     3241 tgctaagagt ccaaacagtc ggaagtttaa acttaatttc atgtgatttg gaaaaattaa
     3301 aatctttagt agaaatttct attgtagatt ttgaaccatt atctagatgt acacgccaaa
     3361 gttcatactc aaatccagat tcttttaatt tatttaagtt aaaagaatct acaacttttt
     3421 tggcatctaa agctactgta atttctcccc agtactctcc atttttataa ataggattag
     3481 taattaaaaa cacatctcca tttgaaaact ggtctttaga aggaccttct acgactaatc
     3541 ctttgataga atttgctaat gaataagaat aattcagttc ctgtattgga gtattgataa
     3601 tatctttttt gacagaatta gaaaaaaatg cagctacatt atatttttct acaactgaaa
     3661 tatatatgca agaattgttt ttaagaattt catctgcaat aggttttaat ttatctatag
     3721 aataattgtt tgaaactaaa actgatgtca agtctttgct ataattaaat ttttcagtca
     3781 gatttaaaat aatgttattc ttgtagacat ttaacatgtt ttctactact tttgtttctt
     3841 tcttttcttg tttgtcaaaa acataaatag caaatttact aaaacataaa aatgttatta
     3901 atacaataat agtacataca aaaaattttt tagatacatt tttcatatga tataaactcc
     3961 ttccacatac attaaactaa atgataatta ccttttccat tacgtttaac atagtataaa
     4021 gcttcatcag cctgttttaa taaattatct atatctttat tgtcttttac actacatact
     4081 acagctccaa cactacaatg agtttgaatg ataccatcat ctgttagtac ttcagtatgt
     4141 aagcgaatag caatctcatc caataaatcc tccacctctt ctctcgatgt aaaaccagat
     4201 aacaacataa caaattcatc tccaccatag cgcccaatta aaccattata ttttatctca
     4261 tattcacgaa gtacatatcc aacatttttc aaaaccatat ccccaatttc atgtccatat
     4321 aagtcgttaa tacatttcaa atcatctaaa tcaacaaatg aaattacaga taatttatca
     4381 ttttcctcca tttcaacacg attataaatt tggtcaaaaa atacagtacg tgttacaaca
     4441 ccagttaatc catcagtcag acctttactt gtgagctgaa taatttcttt aaagtctact
     4501 tcactaggtc tttctgtttg atatatacgt ttttctaatt cttgaacaga acctaaaagc
     4561 atatcaataa cttccattcg ttttttcatg aagcttttct ccatacaaat caaaataata
     4621 aatactaaag ttataacaga tagaatagct cccataggaa ttaaatttaa tgcaaaaata
     4681 tctaagaaat taactttaca aaataaactc caatttgtgt tcttaattgg tttataggac
     4741 ataaagtata attttccatt ttcaaaagcc caataatcac ctgatttatt attaaacata
     4801 tccttttcta ctttttttgc attggttcca agatattttg ttttctgcga taacttcata
     4861 tacttctctc catatgcagt ttcatcactt gttaaattca ttatttgatt ttcacttcca
     4921 aataatatga aattctgttg ctgttgacct tttccttgtt tgagtatatc ctttatctca
     4981 tcaaagtaaa ttgctgcaaa tacacaacca tctacatttc cattctttat tataggtgat
     5041 gcaatagtgt agtttaaagt ttttccatca gcccctgctg caaaactatc tgtaacttga
     5101 tatttttttg ttgcaaaaag tttctgcata taatcacgac cagctagact aatattacca
     5161 ccttcttcat cccatacaat tatattctta tcaacaaaac atatcatcat atacccaaat
     5221 tcatcactat acattgaaag ttctttactt ttatctatgc cattcacact attatctatt
     5281 atgtaattat ctttactcaa agagttcaat agcttaattg tttctcctac cctatcttca
     5341 atacgatttg acgttgtaga taataaatct tgattatctt ttttcataac ccatattgta
     5401 tttatacaaa acatagaaag aataattaat ataattacta tatagaaagt tataaaatat
     5461 tttgctagag attgaaatga aagttcactt gacttatcta tatttctttt tttgtacctc
     5521 ataattccta cccccactat agaaaaattg atgaaaatgt tcctattaga accttaataa
     5581 tacattacaa aacacataat ttcaagtaaa acgttaaatt ttcattacta aatataaact
     5641 ttttattaca atattatttt ttatatccta ttatagcca
//
LOCUS       DAMKNB010000147         5533 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.153, whole genome shotgun sequence.
ACCESSION   DAMKNB010000147 DAMKNB010000000
VERSION     DAMKNB010000147.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5533)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5533)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5533
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.153"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            55..171
                     /gene="rrf"
                     /locus_tag="PC494_003503"
     rRNA            55..171
                     /gene="rrf"
                     /locus_tag="PC494_003503"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
     gene            complement(385..1569)
                     /locus_tag="PC494_003504"
     CDS             complement(385..1569)
                     /locus_tag="PC494_003504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HDF3913956.1"
                     /translation="MLSKRLNFITPSYTIGISSKVKEMESNGVKVINLSIGEPDFNVP
                     NNAKSYGIDSLNKDYTKYDLVPGLKILREEICKKLIEENNCNYSIDEIVVSSGAKNSI
                     TNTLLALTDEGDEVLLPKPYWVSYPEMVKLVNAVPVFIDTKKENGFKLTKDELEKSIT
                     DKTKILVINNPSNPTGSVYTKDELIEIVDVCIQNKIYILADEIYEKICYTGEFTSIAS
                     LSEEAKDITITINGFSKSAAMTGLRLGYTASNKTIAKAMSSIQGHLISHPSLTAQYIA
                     YGALKDCSIDIDNMVKTYKSRRDLIKSKLDSIDNVGYVNPNGAFYIFIDLSKVSEKFE
                     YKDSFSIEFCNQFLEEYNVAVVPGIAFGMDKYIRISYACSENTFLSGLDKLKEFVYKI
                     MA"
     gene            1942..4293
                     /locus_tag="PC494_003505"
     CDS             1942..4293
                     /locus_tag="PC494_003505"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside triphosphate reductase"
                     /protein_id="HDF3913957.1"
                     /translation="MVEFVKKRDGRVIPFNEDRITRAIFLAATNVAEREGIVPDYKLS
                     EQLTQEVIKFLNHKYSESVPSVEDIQDSVVKVLIETGHAKTSEEYIIYRTERSRIRNS
                     KTRLMKAIEEITFEDAEDADIKRENANINGNTAMGTMLQYGSTVSKEFCKTHILKPEH
                     SFAHDNGDIHIHDMDFLNMGTLTCCQIDVKKLFNGGFSTGHGFLREPQDIISYGALAA
                     IAIQSNQNDQHGGQSIPFFDYGLAEGVYKTFKKFYIGNLAKALKLFKGIENNDVIKNI
                     VYNTEKETNQKVGLKRDELYLNLEKEKLIQTFDIDDELVNKMQNFAFEESYRETDKKT
                     YQSMEAFIHNLNTMHSRAGAQVPFSSVNFGTDTSEEGRMVTKNLLLSQERGLGNGETP
                     IFPILIFKVKEGINLNPEDPNYDLFKLSCRVSAKRLFPNFSFLDAPFNAKYYKKGEPD
                     TEATYMGCRTRVLSNVCGSETVSGRGNISFTTVNLPRLGIKHGIINNEKANLDGFFEE
                     LDEKINLIIEQLLERLEVQGNKKMKNFPFLMGQGVWKGSDDLGPEDTLKEVIKQGTLT
                     IGFIGLAECLIALIGKHHGESKEAQELGLKIVSHMRHKMDEATDKYKLNFSLMGTPAE
                     GLSGRFTKIDKKVYGEIKGITDKEYYTNSFHVPVYYNISAYDKIEIEAPYHELTNAGH
                     ITYVELDGDPSDNLEAFETVIKAMKDLGIGYGSINHPVDRDPICGFSGVITSNICPVC
                     GRNEDESDIKFERIRRITGYLVGTVDRFNNAKKAEVRDRVKHR"
     gene            4315..4854
                     /gene="nrdG"
                     /locus_tag="PC494_003506"
     CDS             4315..4854
                     /gene="nrdG"
                     /locus_tag="PC494_003506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HDF3913958.1"
                     /translation="MKIRMSSTISYDSIVDGPGLRMVIWTQGCIHNCKECHNPQTHDL
                     CGGFYMDTEEIINKVKSLKLQKGITLSGGEPFLQPEPLEEIAREAKINGLDVWSYTGF
                     TFEQLLDKKNRAYFKNLNLLKQIDILVDGKFIAEKKDISLKFRGSSNQRIIDVQKSLK
                     YKKVFLVEQYMKDDLSIAE"
BASE COUNT         2155 a          628 c          892 g         1858 t
ORIGIN      
        1 ctaggttcta taaacttatt aaaaacttaa tagaaatatt aagcataaag attatgtggt
       61 tacaatagca gagaggatac acctgttccc attccgaaca cagaagttaa gctctctagc
      121 gctgatggta cttggtggga aactgcctgg gagagtagga cgtagccacg taattttttt
      181 gttataataa atttagaatt taacttatat agtttaattt gataatttga tgaaaaaaat
      241 aaaagactta ctgattttta aatctatagg tcttttattt tttatctaac atttaaatta
      301 agttgttgaa tatatcttat attacttacc ttatatatta attaccatta atacattata
      361 tctaattact attcatctaa attattatgc cattatttta tatacaaatt cttttaattt
      421 atctaatcca gataagaaag tattttcact gcaagcatag gatatacgaa tatatttatc
      481 cataccaaat gctatgccag gaacaactgc aacattatat tcttctaaaa attgattaca
      541 aaattctata gaaaaactat ctttatattc aaatttctca gatactttag aaagatctat
      601 aaatatatag aatgcgccat ttggattcac atatcctaca ttatcaatag agtctagttt
      661 tgatttaatt aaatctcttc ttgatttata tgttttaacc atattgtcta tgtcaattga
      721 gcaatctttc aaggctccat aggctatgta ttgtgctgtt agacttgggt gagatataag
      781 atgtccttgt atagaactca ttgctttagc aatcgtttta ttagatgcag tatatcctaa
      841 tcttaatcca gtcattgcag ctgacttaga aaaaccattt atagttattg ttatatcttt
      901 agcttcttcg cttaatgatg caattgatgt aaattcacca gtgtagcata ttttttcata
      961 tatttcatct gctaaaatat atattttatt ttgtatgcat acatctacta tttctattaa
     1021 ttcatctttt gtataaacac taccagtagg atttgaagga ttgtttatta caagaatttt
     1081 tgttttatct gttatagatt tttcaagttc atcttttgtt aacttaaatc cattttcttt
     1141 tttagtatca ataaaaactg gaacagcatt aactaactta accatttcag gataactaac
     1201 ccaataaggc tttggtaata agacttcatc tccttcgtct gttaaagcta gtaaagtatt
     1261 tgttattgag ttttttgctc cacttgatac aactatttca tctattgaat agttacagtt
     1321 attttcttca ataagttttt tacagatttc ctctctaagt atttttaatc ctggaactaa
     1381 atcatattta gtgtaatctt tatttaaaga atcaatacca taagattttg cgttattagg
     1441 tacattaaaa tcgggttctc ctatactaag atttattact ttaactccat tactttccat
     1501 ttctttaact ttagaactaa tacctattgt gtaggatggt gttataaagt ttagtctttt
     1561 tgataacata aaatgcctcc ttttaaatta ttatttatat tatacgacaa atttaaagaa
     1621 tttacataag gaaatttgta gatatataca ttaatatata taatagccta cactttttgc
     1681 ctaaaattag tgtaaaaaaa agagaaaaaa attttaactt tcaaagttgt tagaaacgct
     1741 actgttcaaa atatccacat agtatttgca atgatttgcg caagtttgac tattatgtac
     1801 aaatttggta atcttaatat agcaattatt aagataatcc ctttaactta gttgaagggg
     1861 atttttttag acttaacata ctacatatag tggtatgggg attaataaaa tacaatatat
     1921 agtaacagga ggttttttta attggttgaa ttcgtaaaaa aaagagatgg aagagtaatt
     1981 ccatttaatg aagatagaat aacaagagct atatttttag cagcaacgaa tgttgcagaa
     2041 agagaaggaa tagtacctga ttataaatta tctgagcaat taactcaaga agtaataaag
     2101 tttttaaatc ataaatactc agaatcagtt ccaagtgttg aagatataca agattctgta
     2161 gttaaggttc ttatagaaac tggccatgca aaaactagtg aagaatatat aatatacaga
     2221 actgaaagaa gtagaataag aaattcaaaa acaagattga tgaaggcaat agaggaaatt
     2281 acctttgaag atgcagaaga tgctgatata aaaagagaaa atgcaaatat taatggtaat
     2341 acagcaatgg gaactatgtt acaatatgga agcactgtat ctaaagaatt ttgtaaaaca
     2401 catatattaa aaccagagca ttcttttgct catgataatg gagatataca catacatgat
     2461 atggattttt taaatatggg aacattaact tgttgtcaaa tagatgttaa aaaactattc
     2521 aatggtggat tttcaacagg acatggcttt ttaagagagc cacaagatat aataagttat
     2581 ggtgcattag ctgcaattgc tatacaaagc aatcaaaacg atcaacatgg aggtcaaagt
     2641 ataccatttt tcgattatgg attggctgaa ggtgtatata agacatttaa gaaattctac
     2701 ataggaaatt tagctaaagc attgaagtta tttaaaggaa ttgaaaataa tgatgtgata
     2761 aagaacatag tatataatac agagaaagaa acaaatcaaa aagttggtct taagagagat
     2821 gaattgtatc taaacttaga aaaagagaaa ttaatacaga cttttgatat agatgatgaa
     2881 cttgtaaata agatgcaaaa ctttgcattt gaagaatcgt atagagaaac tgataaaaaa
     2941 acatatcaat ctatggaagc atttatacac aatctaaata caatgcactc tagagcaggt
     3001 gcacaggtac cattttcaag tgtaaacttc ggaacagata cttctgaaga aggaagaatg
     3061 gtaactaaga atcttctatt atctcaagaa agaggtttag gtaatggaga gacaccaatt
     3121 tttccaattt taatatttaa ggtcaaagaa ggcataaatt taaatcctga agaccctaat
     3181 tatgatttat ttaaattatc atgcagagta tcagctaaaa gactattccc taattttagc
     3241 tttttagatg cgccttttaa tgcaaaatat tataaaaaag gtgaaccaga tacagaggct
     3301 acatatatgg gttgtagaac aagagtactt agtaatgtgt gtggttcaga aacagttagt
     3361 ggtagaggaa acatatcttt tactacagta aatttaccaa gattgggtat aaaacatggt
     3421 attataaata atgaaaaggc taatttagat ggtttctttg aagaattaga tgagaagata
     3481 aacttaatta tagaacaatt attggagcgc cttgaggtac aaggaaataa aaagatgaag
     3541 aattttccat tcttaatggg gcaaggtgta tggaaaggtt ctgatgattt aggaccagaa
     3601 gatacactaa aagaagtaat aaaacaagga acattgacaa ttggatttat aggtttagca
     3661 gagtgcctta ttgctcttat aggtaaacat catggagaaa gtaaagaagc tcaagaatta
     3721 ggattaaaaa tagtgtcaca tatgagacat aaaatggatg aagcaacgga caaatataaa
     3781 ttaaatttct ccttaatggg tactccagca gaaggtcttt caggtaggtt tactaaaata
     3841 gataaaaaag tttatggaga aattaaaggt atcacagata aagaatatta tactaattca
     3901 ttccatgtac cagtttatta caatataagt gcatatgata aaattgagat agaagctcca
     3961 taccatgaat tgactaatgc aggtcatata acatatgtag agttagatgg agatccatct
     4021 gataatttag aagcttttga aactgttata aaagctatga aagatttggg tataggatat
     4081 ggaagtataa atcatcctgt agatagagac ccaatatgcg gtttttcagg tgtaataaca
     4141 agtaatatat gccctgtatg tggaagaaat gaagatgaaa gtgacatcaa attcgaaaga
     4201 ataagaagaa taacaggata cttagttggt acagttgata gatttaataa tgctaaaaaa
     4261 gcagaagtaa gagatagagt aaaacataga tagttttatt tgggggaata agttatgaaa
     4321 ataagaatgt catctactat aagttatgac agcatagttg atggaccagg attaagaatg
     4381 gtaatatgga ctcaaggatg tattcataat tgtaaagagt gccataatcc tcagacacat
     4441 gatttatgtg gaggatttta tatggataca gaagaaatta taaataaagt caaatcattg
     4501 aaattacaaa aaggcattac gctatcagga ggagaaccat ttttacaacc agaaccatta
     4561 gaagaaatag caagagaagc taaaataaat gggttagatg tatggtcata tactggattt
     4621 acgtttgaac aactgttaga taaaaaaaat agagcgtatt ttaaaaattt aaatttacta
     4681 aagcaaattg atattttagt ggatggaaaa tttatagctg aaaaaaaaga tataagctta
     4741 aagtttagag ggtcatcaaa tcaaaggata attgatgttc aaaaaagttt gaaatataaa
     4801 aaagtgtttt tggttgagca atatatgaag gatgatttat ctatagcaga ataaaatata
     4861 aataaacagg attaaatata tgcatatatt taatcctgtt tattttcata taatatttca
     4921 agcttgtata atgtaacaat taaaccaaaa gactcattgt atatttgaaa ttaagttttt
     4981 tatagtttat aggtgtttta tgtggattac gaatgatata gtattgatac attatttaat
     5041 agattcttat gccaagaaac aattaattta tagaaattct taattgttac aatataaata
     5101 tctagataag ttataagata ctgataaata atttataaag tttattaatc taatattgtg
     5161 tgtgaatatt aagtggtcaa gtagtctaaa aaatgaaaaa gatttaaaaa agtgttttaa
     5221 ctaaacacat aggtgttaaa ttcatgtata agtataggtt agatacataa gaaataatta
     5281 tgtaatatct atctttgtaa aaaaatatta aattttgtaa tttgtggata aatatgttta
     5341 taatgtggat aatatttaat gtaataagtt aaagcaatat gaatcaactg tttataatgt
     5401 ggataatatt ataaatgtat gaataattgc agtatttaaa aacaaaaaaa gttaaaaaag
     5461 ttgttgactc taaaagaaaa agttggtata gtaatacttg tcctcaagaa aagggcaaac
     5521 aaataaagca taa
//
LOCUS       DAMKNB010000148         5509 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.154, whole genome shotgun sequence.
ACCESSION   DAMKNB010000148 DAMKNB010000000
VERSION     DAMKNB010000148.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5509)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5509)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5509
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.154"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            complement(120..1061)
                     /locus_tag="PC494_003507"
     CDS             complement(120..1061)
                     /locus_tag="PC494_003507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase family protein"
                     /protein_id="HDF3913959.1"
                     /translation="MSKMATREAYGKALVKLGQINDNVVVLDADLSKSTKTHDFYKSF
                     PDRFFNMGIAEQNLIGAACGLSTAGKIPFASTFAMFATGRAFEIIRNSVCYPKLNVKI
                     CATHAGLTVGEDGASHESVEDIAIMRAIPNMTVLVPADGVETEKIIFEIAKYNGPVYV
                     RLGRSSVPVLFDEDYKFEIGKGTVLREGKDVSIIACGIMVNEALLAQEKLQEEGISAR
                     VINMSSIKPIDKDLILESAKETNAIVTVEEHSIIGGLGSAVSEVVGESCPTIVKKVGI
                     KDTFGESGTPNELLKKYELTCDDIIKTVKEVIIAKRM"
     gene            complement(1054..1881)
                     /locus_tag="PC494_003508"
     CDS             complement(1054..1881)
                     /locus_tag="PC494_003508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HDF3913960.1"
                     /translation="MRDHKGLNEIARIIRRDIVSMIHRAKSGHPGGSLSVVEILTALY
                     FDEMNVDSSNPKMEDRDRFVLSKGHAAPALYATLAEKGYFDKEELNGLRKIGRMLQGH
                     PDMKGTPGVEISTGSLGQGFSVACGMAMASKLDNAPWNVYTLLGDGEVQEGIVWEAAM
                     SAAHYKLDNLIAFLDNNGLQIDGDIESVMSLGSIVDKFKAFGWNVIEIDGHDFDQIFA
                     ALDIAKSTVKKPTMIVAKTIKGKGISFMENQAGWHGTAPSDEELEKALLELGGADNE"
     gene            complement(2052..2435)
                     /locus_tag="PC494_003509"
     CDS             complement(2052..2435)
                     /locus_tag="PC494_003509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HDF3913961.1"
                     /translation="MKGRLPKVSTNCEIKRGDLYYADLSPVVGSEQGGVRPVLIIQND
                     VGNKYSPTVIVSAITSQINKAKLPTHVEISSNEYGLNKDSVILLEQIRTIDKKRLREK
                     IGCLDENMMIKVDDGLQISLGLFTF"
     gene            complement(2404..2691)
                     /locus_tag="PC494_003510"
     CDS             complement(2404..2691)
                     /locus_tag="PC494_003510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribbon-helix-helix protein, CopG family"
                     /protein_id="HDF3913962.1"
                     /translation="MYDKSKEKIEVTLPDSLISEVDSIVQMENSNREDFAKAAFQFYI
                     TQKKKIHIKESMKTGYREMGQINLSLAELGMTVEEVSSDDKNEGKIAQGEY"
     gene            complement(2724..3881)
                     /gene="alr"
                     /locus_tag="PC494_003511"
     CDS             complement(2724..3881)
                     /gene="alr"
                     /locus_tag="PC494_003511"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HDF3913963.1"
                     /translation="MQKITVPTWAEINLDNLRFNLNNIKNLLEEDIKICGVIKADAYG
                     HGAVEVAKLLEKEKVDYLAVARTAEGIELRQNGITLPILNLGYTPDEAFEDSIKNKIT
                     MTVYSLETAQKINEIAKSLGEKACVHVKIDSGMTRIGFQPNEESVQEIIELNKLEYID
                     LEGMFTHFATADEVSKEYTYKQANNYKFMSDKLDEAGVKIAIKHVSNSAAIMDCPDLR
                     LNMVRAGIILYGHYPSDDVFKDRLELRPAMKLKSKIGHIKQVEPGVGISYGLKYTTTG
                     KETIATVPIGYADGFTRIQKNPKVLIKGEVFDVVGRICMDQIMVRIDKDIDIKVGDEV
                     ILFGEGEVTAERIAKDLGTINYEVLCMISRRVDRVYMENNELVQINSYLLK"
     gene            complement(3896..4486)
                     /locus_tag="PC494_003512"
     CDS             complement(3896..4486)
                     /locus_tag="PC494_003512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3913964.1"
                     /translation="MRKKWTIVCIMFLALVIIVIGCQKRQSTKEEVYKDFQKQISDMN
                     YYSCKAEVEVVGNKSPHNYVLIHTYKKTDNYKLEVISPKHLKGKSIEYQGDKILVKNP
                     KISDVVELPNTGKNNQYLFVGDFIKNYLQNEEMKVKLSKGHLVLETFIPGDNKYFNKQ
                     VLYVNADTKNPEKMEVLDKEGVPRFTVKYKDFEYRN"
     gene            complement(4507..4968)
                     /locus_tag="PC494_003513"
     CDS             complement(4507..4968)
                     /locus_tag="PC494_003513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HDF3913965.1"
                     /translation="MMDKTAKEIMTTDVIVAKQDDSIADVANMLIAEKIGGLPVVDSE
                     NRVVGIISETDILKKEKYIEAPLYINLLQGLIFLDDLKKVEKDIKQVAAYKVGELMSK
                     DIIKVHEDDKFDDVANVMIKKSINRVPVVDDDNKLKGIICRYDIIKALYNE"
     gene            complement(4983..5363)
                     /locus_tag="PC494_003514"
     CDS             complement(4983..5363)
                     /locus_tag="PC494_003514"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HDF3913966.1"
                     /translation="MNIFDIGVDIIEIDRIRKAVDKNNRFLEKIFTDREIEYFNSKNF
                     KAESIAGNFAAKEAISKSIGTGIRLFNFKDIEVLRNEMGKPIVKTYNNLAKMCIDYNV
                     LEIKVSISHSKDYAIANAITIIKD"
BASE COUNT         1650 a         1088 c          574 g         2197 t
ORIGIN      
        1 attacatttt tgatatattg atatcatata aaaaaaagag agatataaat taatataaca
       61 ctttatacct ctcttttaaa tatattatat tattaacaaa catgaataat ttatatctct
      121 tacattcttt ttgcaataat aacttcttta acagtcttta ttatgtcatc acaagttaat
      181 tcatattttt ttaacaattc atttggagta ccagattctc caaatgtatc tttaattcca
      241 actttcttta caatggttgg acaagactct cctactacct cacttacagc agaacctaat
      301 cccccaatta tgctatgttc ttctacagtt acaatagcat tcgtttcttt tgctgattct
      361 aatattaaat ctttgtctat aggttttatc gaggacatgt ttataactct agcacttata
      421 ccttcttctt gcaacttttc ttgtgctaat agagcttcat ttaccataat tccacaagct
      481 ataattgata catcctttcc ttctcttaag actgtacctt ttcctatttc aaatttataa
      541 tcttcatcaa ataaaactgg tactgaactt ctccctaatc taacataaac aggtccattg
      601 tacttagcta tttcaaaaat aattttttct gtttcaactc catcagctgg aacaagaact
      661 gtcatatttg gtatagctct cattatagca atatcttcca cactttcatg agatgctcca
      721 tcctctccaa cagtaagacc tgcatgagta gcacatattt ttacatttag ctttggataa
      781 caaactgaat ttcttataat ctcaaaagcc cttcccgtag caaacatagc aaaagtactt
      841 gcaaaaggta ttttaccagc agttgataat ccacaagcag cgcctattaa attttgttca
      901 gctataccca tattaaaaaa tctatctgga aatgacttgt aaaaatcatg tgtttttgta
      961 gactttgata aatctgcatc taatactaca acattgtcat ttatttgacc taattttact
     1021 aatgctttac catatgcttc tctcgtcgcc attttactca ttgtcagcac ctcctaattc
     1081 aagcaaggct ttttctagct cctcatcact tggagctgtc ccatgccatc ctgcttgatt
     1141 ttccataaaa gatattcctt tgccttttat agtttttgca actatcattg taggtttttt
     1201 aactgttgat ttagctatat caagagccgc aaatatttgg tcaaaatcat gtccatctat
     1261 ctcaattaca ttccaaccaa aagctttaaa tttatcaact attgaaccta aactcattac
     1321 gctttctata tctccatcta tttgaagtcc attattatct aaaaaagcaa ttaaattatc
     1381 aagtttataa tgtgcagcac tcatagcagc ttcccaaaca attccttctt gaacctcacc
     1441 atcaccaagc aaagtataca cattccacgg agcattatcc aactttgatg ccatagccat
     1501 accacatgca actgaaaaac cttgacctaa agaaccagta gatatttcca cacctggcgt
     1561 gcctttcatg tctggatgac cttgtaacat ccttcctatc ttccttaatc cattcagttc
     1621 ttccttatca aaataacctt tttcagccaa tgtagcatat aatgctggtg cagcatgtcc
     1681 ttttgataat acaaatctat ctctatcctc cattttagga tttgaagaat ccacattcat
     1741 ttcatcaaag tataacgcag taagtatttc aactactgat aatgaccctc ctggatgtcc
     1801 agatttggct ctatgtatca ttgaaactat atctcttctt atgatacgcg caatctcatt
     1861 taatccttta tggtctctca tgcaattacc tcccttgagt tcgtaatttt atatcaattc
     1921 catattatta tatcactttt atgctatttt tttgcgttat ttttaatttt attaacatag
     1981 tacattaaaa ttaaacctta agagatattt aaaagaaaaa agggattgtc taataaaaga
     2041 caaatccctc tttaaaaagt aaacaatcct aaacttattt gaagtccatc atctactttt
     2101 atcatcatat tttcatctag acaaccaatt ttttccctca gtctcttttt atcgatagtt
     2161 ctaatttgct ctaaaagaat tactgagtct ttattaagcc catattcatt ggaacttatc
     2221 tctacatgag taggtaattt ggctttatta atctgagatg ttatagctga tactataact
     2281 gtaggactat atttattacc tacatcattt tgtattatca gaacaggtct aacgcctccc
     2341 tgctctgaac caacaactgg acttaaatca gcgtaatata aatcaccacg ctttatttca
     2401 caattagtac tcaccttggg caatcttccc ttcattttta tcatcagaag atacttcttc
     2461 aactgtcata cctaattcag ctagtgacag attaatttga cccatttctc tataacccgt
     2521 tttcatagat tctttaatat gaattttctt tttctgagtt atatagaact gaaaagcagc
     2581 ttttgcaaaa tcttctctgt tactgttctc catctgaact atactatcaa cttcagaaat
     2641 cagagagtca ggtaaagtaa cttctatttt ttctttactc ttatcgtaca caaaatcgcc
     2701 tcccagatta taatatcatg gttttatttt agcaaataac tgtttatttg tacaagctca
     2761 ttattttcca tataaacacg gtcaactctt cttgatatca tacataacac ttcatagttt
     2821 atagttccta agtctttagc tatacgctca gctgtaactt cgccttctcc aaatagtata
     2881 acctcatctc caacttttat gtctatatct ttgtcaattc taaccattat ttgatccata
     2941 catattctac caactacatc aaacacttct cccttaataa gaacctttgg atttttttgg
     3001 attctagtaa atccatctgc gtatcctatt ggaactgtag ctattgtttc tttacctgta
     3061 gttgtgtatt ttagtccata acttattcct acacctggtt caacttgttt tatatgtccg
     3121 atttttgatt ttaatttcat ggctggtctt aattctaatc tatctttaaa tacatcatca
     3181 gatggataat gaccatataa tattattcct gctcttacca tatttaatct taaatcaggg
     3241 caatccataa tagctgcact gtttgataca tgttttatag ctatttttac accagcctca
     3301 tctaatttat cagacataaa tttataatta ttagcttgtt tataagtgta ctctttactt
     3361 acttcatcag ctgtagcaaa atgagtaaac ataccttcta aatctatata ttctaattta
     3421 tttaattcta ttatttcctg tactgactcc tcattaggtt ggaaacctat tctagtcatc
     3481 cctgagtcta ttttaacatg aacacaggct ttttctccta aagattttgc aatttcattt
     3541 atcttttgtg ctgtttctaa agaataaact gtcatagtta ttttattttt tatagaatct
     3601 tcaaaagctt cgtctggagt atatcccaag ttcaaaatag gaagtgttat gccattttgt
     3661 ctaagttcaa ttccttcagc agttcttgct actgctaagt aatctacttt ttctttttct
     3721 agcaattttg caacttctac tgcaccatgt ccatatgcat cagcttttat tactccacaa
     3781 atcttaatat cttcttctaa taaattttta atattattta agttaaatct taagttatct
     3841 agatttatct ctgcccatgt aggcactgtt attttttgca tgtctttagt cccccttagt
     3901 ttctgtattc aaaatctttg tattttactg taaatcttgg cactccctct ttatctaaca
     3961 cttccatttt ttcaggattt tttgtgtcag catttacata taatacttgc ttgttaaaat
     4021 atttattatc cccaggaata aaagtctcta aaaccaaatg tcctttggat aactttactt
     4081 tcatctcctc attttgaaga tagtttttta taaagtctcc tacaaaaaga tattgattat
     4141 tttttcctgt attaggtaac tccactacat cactaatctt tggattttta actaatattt
     4201 tatcaccttg atattctata cttttccctt ttaaatgttt tggggaaatt acttctaatt
     4261 tatagttatc ggttttttta taagtatgaa ttaaaacata attgtgtgga cttttatttc
     4321 caactacttc tacttcagct ttacaactgt aataattcat atcagaaatc tgcttttgaa
     4381 aatctttgta tacttcttct tttgtggact gtcgtttttg gcatcctatt acaattataa
     4441 ccagtgccaa gaacataata catactatgg tccacttttt tctcacatca cacctcctac
     4501 ttcagtttat tcattgtata aagcttttat tatatcatat ctacaaatta tacctttaag
     4561 tttgttgtca tcatctacta caggaactct gtttattgat tttttaatca ttacattagc
     4621 tacatcatca aacttatcat cttcatgaac ctttattata tctttagaca taagttctcc
     4681 aaccttataa gcagctactt gttttatatc tttttcaact ttttttaagt catctaagaa
     4741 aatcaatcct tgtaatagat ttatatagag aggtgcttct atatattttt cttttttaag
     4801 aatatctgtt tcagaaatta ttccaacaac tctattctct gaatctacaa ctggcagacc
     4861 tcctattttt tctgcaatta gcatattagc tacatctgct atactatcat cttgttttgc
     4921 tactattaca tctgttgtca ttatttcttt tgctgtttta tccatcataa tgtaatcact
     4981 ccttagtcct taattatggt tatcgcattt gctatagcat aatcttttga atgtgatatt
     5041 gaaactttta tttctaaaac attataatct atgcacattt ttgctagatt attataagtt
     5101 tttactattg gttttcccat ttcatttctg agaacttcta tatctttaaa attaaacaat
     5161 ctaattcctg tacctataga tttacttata gcttccttgg ctgcgaaatt acctgctata
     5221 ctttctgctt taaaattctt agaattaaaa tactctattt ctctatctgt aaatatcttc
     5281 tccaaaaacc tattattttt gtctacagcc tttcttattc tatcaatttc aattatatct
     5341 acgccaatat caaatatatt cattgttcct ccagaaaatt tataatactt ctttcaataa
     5401 ttaataatga atttataaat ttactatcga taatacacat tattatttag tttatgttac
     5461 ttatcttaat ttaataatca ttataataaa actgtaactt ttaaaatta
//
LOCUS       DAMKNB010000149         5410 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.155, whole genome shotgun sequence.
ACCESSION   DAMKNB010000149 DAMKNB010000000
VERSION     DAMKNB010000149.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5410)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5410)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5410
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.155"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            270..1733
                     /locus_tag="PC494_003515"
     CDS             270..1733
                     /locus_tag="PC494_003515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine:cation symporter family protein"
                     /protein_id="HDF3913967.1"
                     /translation="MTDLVNTINGIVWSPVLVAMCLCIGLYFSLKLKFFQIRDVKEMF
                     TLLLEGDSSHVGISSFQGFATSMAGRIGTGNIAGVAVAIAMGGPGALVWMCIMATLGS
                     ATAFVESTLAQIYKDEHDGQYRGGPPYYFEKGLGWKKCSVLFSIVAIISYTFFMPGTQ
                     SNTLYLAMNQAFGFSKMTIAVASSIALAIIIFGGIKRIGLFAEKVVPIMGGAYLIMTL
                     VIIITNISLVPEAIVTMFKSAFGFGSVFGGMLGSAISWGVKRGIYSNEAGEGSGTYGA
                     AAAEVSHPAKQGLVQAFSVYVDTLLICMATGIMIVITGMYNVTGVCTALPGVEPGPQY
                     VQSAINTLHTQLGDIFIAIVLLLFTFTTLLAFSYMMETNVSYLVTRIKAEKHEKYIIN
                     VCRFMLIACAAMCCFIEPLTSWALGDICIGVLTYINLIAIFTLKKPAIKAYYDYIRQK
                     KMGIKRSDRTFNPIELDIRNAEFWENRYLKEDKHELN"
     gene            1789..2925
                     /locus_tag="PC494_003516"
     CDS             1789..2925
                     /locus_tag="PC494_003516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HDF3913968.1"
                     /translation="MKERIIQVADSKKEKILGLCQSLYDEPEIALQEYKSAKKISEFL
                     REEGFDVEENLAGMATAFKATKKNGDGPKIAFIAEYDALPGNGHACGHHLIASMGVGA
                     GIALSSILDTYKGEVSIIGTPAEETGDGKPYLIEHGVFDGYDAAMMIHPNSKTCVTPE
                     IIAIGGLDFIFTGKASHAGAKPYNGINALDAVVLLYNNINALRQQLVDGTRIHGIILE
                     AGTAANVIPDMGKVRLEIRAKEQNYFDEVVEKVKNCARGAAIATGCELEFYHFEPTCQ
                     GLNENKVLVDIFTKIMEEFGIYEDEQVMLGSTDMGNLSQIMPCIHPLMKFSENGEELH
                     TKEFLEASINSYAKDRVIDGIKILALTGFNLFENPELLKKMKEE"
     gene            3161..4276
                     /locus_tag="PC494_003517"
     CDS             3161..4276
                     /locus_tag="PC494_003517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="linear amide C-N hydrolase"
                     /protein_id="HDF3913969.1"
                     /translation="METLEVRNIELSGTNYEIGYRLGELVANMPEIIEGQINKSNLVS
                     KKEEKEMIELFDKYCPGLNEELQGFADAIQVNCNQILYYTMTYLKPGCSQVALAPELT
                     ENGHVLFARNFDFSHNMEDFVLCKTKVNGKYAHIGTTIMQFGRGEGMNECGLGVSQSS
                     CGIPVGNSDGLRKPAIVGLQFWAVIRYLLENCKDVDEALEYLKDMPIAYNINLLLADK
                     SGNIALVETLDGKKEVNIINSLESKREYFLHSTNHTHIDKLHKLDPQSMKNSIHRYKL
                     IKEYINKSKKIGEKELMNLLSSKYPNGLSCNYYNDFFGTLKSIVMDLNIGKFNILWGG
                     LENKWESYYLKNDIKSITQRININIEKAPSDFFDFIE"
     gene            4428..5297
                     /locus_tag="PC494_003518"
     CDS             4428..5297
                     /locus_tag="PC494_003518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HDF3913970.1"
                     /translation="MDYLKYFEKAVMYIENNLHENITVNDVAKETGYSYYHLTRLFKS
                     MFGESVGSYIKKRRLVSSTKELLYSDKKVIDIAIGSGFESSEAFSRAFKSIYKVSPIE
                     YRKNRIDVFVGKKKKLELDFMRHLVGNITIKPVIKEIEKIKVIGIKDKVILENNSLPD
                     LWEKFRKVHHIVPNTLPSKRVFGICEAISEIHLVSESMEFNEIIGLEVNSYDVIPNSF
                     VSKTIKEGKYAIFTHTGSLDNLDKTYEYIWGTWLLSSKEELDIRDDFEVYDERFLGPS
                     NVNSQIDIYIPIK"
BASE COUNT         2081 a          554 c         1009 g         1766 t
ORIGIN      
        1 aatttcaggc ttttcattat atgtattcca atttatattg tttgattatt attcaaacac
       61 acgtcgttaa aaattttata aatttatgtt tagatatgat taatactctt gattttagaa
      121 ataaatattt gtagattgta gattaaagat aatataaata aatagaaggt agatttttta
      181 gatatattaa tataaagatt atgtaaaata ttgaaatata gctgtttaaa ttattgtcta
      241 taaatataaa atgaatggtg gtgagttaag tgaccgattt agttaacacc attaatggaa
      301 ttgtttggtc acccgtatta gttgcaatgt gtttgtgtat aggattatat ttttcattga
      361 aattaaaatt ttttcaaata agagatgtaa aagaaatgtt tactctcttg cttgaaggag
      421 atagttctca tgttggtata tcatcatttc aaggttttgc tacatctatg gctggaagaa
      481 tagggactgg aaatatagct ggtgtagctg tagcaatagc aatgggaggt ccaggagcat
      541 tagtatggat gtgcataatg gctacattag gttcagcaac tgcatttgta gaatctactc
      601 tagctcaaat atataaagat gagcatgatg ggcagtatag aggaggacct ccatattatt
      661 ttgaaaaagg tcttgggtgg aaaaagtgtt cagttttatt ttcaatagtt gcaataataa
      721 gttatacatt ttttatgcct ggtacacaat caaacacttt atatctagca atgaatcaag
      781 catttggatt ttcaaaaatg acaatagcag tagcatcttc tattgcatta gcgataataa
      841 tttttggagg aattaaaagg attggtttat ttgctgaaaa agtagtacct ataatgggtg
      901 gagcatacct tattatgaca ttagtaataa ttataacaaa tattagttta gttccagagg
      961 ctattgtaac aatgtttaaa tctgcatttg gatttggttc agtttttgga ggaatgctag
     1021 gttcagcaat atcttgggga gtaaaaagag gtatatactc aaatgaagca ggagaaggtt
     1081 ctgggactta tggtgcggca gcagcagaag taagtcatcc agccaaacaa ggattagttc
     1141 aagcattttc tgtttatgta gacacattat taatatgtat ggctacaggt attatgattg
     1201 taataacagg aatgtataat gttacaggtg tttgcacagc actaccaggt gtagaaccgg
     1261 gaccacaata tgtacagagt gcaataaata cattacatac acaattaggt gatattttta
     1321 tagcaatagt tttattatta tttacattta caactttatt agccttctca tatatgatgg
     1381 agactaatgt atcttactta gtaactagaa ttaaagcaga aaaacatgaa aagtacataa
     1441 ttaatgtctg tagatttatg cttatagcat gtgcagcaat gtgttgtttt atagaaccac
     1501 ttacaagctg ggcattaggt gatatatgta taggtgtatt aacatatata aatttaattg
     1561 ccatctttac actaaaaaaa ccagctataa aggcatatta tgattatata agacagaaga
     1621 agatgggaat aaaaaggagt gatagaactt ttaaccctat agagttagat ataagaaatg
     1681 ctgagttttg ggaaaataga tacttaaaag aggataagca tgagttaaat taaagttata
     1741 ataaaatata aaaattacta aataaattta gtgggaggta agattggtat gaaagaaaga
     1801 ataatacaag tggctgattc aaagaaagaa aaaattctag ggctatgtca atctttatat
     1861 gatgaaccag aaattgcttt gcaagaatat aaatctgcta aaaaaatatc agaattttta
     1921 agagaagagg gttttgatgt tgaggaaaac ttggcaggta tggctacagc ttttaaagca
     1981 accaagaaaa atggagatgg tcctaaaata gcatttatag cagaatatga tgctcttcca
     2041 ggcaatggac atgcatgtgg acatcattta attgcatcta tgggagttgg agctggaata
     2101 gctctttcaa gtatactgga tacttacaag ggagaagtaa gtataattgg aacacctgct
     2161 gaagaaactg gagatggaaa gccttacttg atagaacatg gtgtatttga tggctatgat
     2221 gcagcaatga tgatacatcc taattcaaaa acttgtgtaa cacctgaaat tatagcaata
     2281 ggaggtctag atttcatatt tactggaaaa gcatctcatg caggagctaa gccatataac
     2341 ggaataaatg ctttagatgc agtagtacta ctatataata atataaatgc actaagacaa
     2401 caattagtag atggaacgag aatacatggt attatactag aagcaggaac tgctgcaaat
     2461 gtaatacctg atatgggaaa agtaagatta gagataaggg caaaagaaca aaattacttt
     2521 gatgaagtag tagaaaaagt gaaaaattgt gctagaggtg ctgcaatagc cactggatgt
     2581 gaacttgaat tttatcactt tgaaccaact tgccaaggat taaatgaaaa taaagttttg
     2641 gtagacatat ttacaaagat tatggaggaa tttggaatat atgaagatga acaagtaatg
     2701 ttaggttcaa cagatatggg aaatttaagt caaataatgc catgtataca tcctttgatg
     2761 aagttttctg aaaatggaga agaactacat acaaaagaat ttttggaggc ttctataaat
     2821 tcatatgcaa aagatagagt aattgatggt ataaaaatat tagctttaac aggatttaat
     2881 ttatttgaaa atccagagtt attgaaaaaa atgaaggaag agtagaactt agactatttt
     2941 taattatact ctttaaaata agaagagtgt ctcaaaagga actttttagt ttatgagaca
     3001 ctcttttttg tatgaaatta aatatatttt tattatttta aacatgaaaa agaggcttat
     3061 ctgtttttat atgacctttt ttaacttgta gcacaaaata tcatgaatga ttacaattcg
     3121 aatgataaaa tcgattataa gatatatagg aggggtacat gtggaaactt tagaagtaag
     3181 aaatattgaa ttgagtggta caaattatga gataggatac agactaggag aattggttgc
     3241 taatatgcca gagataatag aaggtcagat taataaatct aatctggtaa gcaaaaaaga
     3301 agaaaaagag atgatagagt tgtttgataa atattgtcca ggtcttaatg aagaattgca
     3361 aggttttgct gatgcaattc aagtgaattg taatcaaatt ttatattata ctatgactta
     3421 tcttaaacca ggttgtagtc aagttgcatt agcaccagaa ttaactgaaa atgggcatgt
     3481 actatttgca cgtaatttcg atttctcaca caatatggag gattttgttt tatgtaaaac
     3541 taaggtaaat ggaaaatatg cacatatagg tactaccatt atgcaatttg gaagaggtga
     3601 aggtatgaat gaatgtggct taggtgtaag tcagtcatca tgtggtattc ctgtaggcaa
     3661 ttcagatggt ttaagaaaac cagcaattgt aggtttacag ttttgggctg ttattagata
     3721 tttgttagaa aattgcaaag atgtagatga agcattagaa tatttaaaag atatgccaat
     3781 tgcatacaat attaatttat tgcttgcaga taagtctgga aacattgcac ttgtggagac
     3841 tttagatggg aaaaaagaag taaatataat caacagttta gaaagtaaaa gagaatattt
     3901 tttacactct actaatcata cacatattga taaacttcat aaattagatc cacaatcaat
     3961 gaaaaattct attcatagat ataaattaat taaagaatat ataaataagt ctaaaaaaat
     4021 tggagagaaa gagttaatga atttattgtc ttcaaaatat ccaaatggct tatcttgtaa
     4081 ttactataat gatttttttg gaactttaaa aagtatagtt atggatttaa atataggaaa
     4141 gtttaatatt ttatggggtg gactagagaa taaatgggag agctactatt taaaaaatga
     4201 cattaaatct ataacacaga ggataaacat aaatattgaa aaagcaccat ctgacttttt
     4261 tgatttcatt gaataaaaaa tgtattcaat tattctaaat aattaggata tataaatcaa
     4321 ctaaaagttt ttatttatcg tattgaatta gttataatat tttagtatag taaaaaatag
     4381 tgctatttta catatttaaa gagtttaagt agaagagagg tgccatattg gattacttaa
     4441 agtattttga aaaagctgta atgtatattg agaataattt acatgaaaat ataactgtaa
     4501 atgatgtggc aaaagaaact ggatattctt attatcattt aacacgctta tttaagtcta
     4561 tgtttggtga gagtgtagga agttatataa aaaaaagacg attagtaagt agtacaaaag
     4621 aacttttata tagtgataaa aaagtgatag atatagctat tggtagtgga tttgaatctt
     4681 cagaagcatt tagcagagca tttaaatcta tatacaaggt tagccctata gaatatagaa
     4741 aaaatagaat tgatgtattt gttggtaaaa agaaaaaatt agagttagat tttatgagac
     4801 atcttgttgg aaatataacg attaaaccag ttataaaaga aatagaaaaa ataaaggtaa
     4861 taggtataaa ggataaagta attttagaaa ataattcatt acctgacttg tgggagaaat
     4921 tcagaaaagt acatcatatt gtcccaaata ctttgccatc aaagagagtt tttggaatct
     4981 gtgaagcaat ctctgaaata cacctagtta gtgaaagtat ggagtttaat gagataatag
     5041 gacttgaagt taatagttat gatgtgattc caaattcatt tgtttcaaaa actattaagg
     5101 aaggaaagta tgctatattt actcatactg gtagcttaga taatttagac aaaacttatg
     5161 aatatatatg gggtacttgg cttttaagtt caaaagaaga acttgatata agagatgatt
     5221 ttgaagtata tgatgaacga tttttaggtc ctagtaatgt gaactcacaa attgatattt
     5281 atatacctat aaaataatct ataagaaaac taaaagataa tttgattaag aaatagatgt
     5341 tcgtaaaaga gcatctattt tttattttta tcagatttag ataattttaa taataaaaga
     5401 aataaaaata
//
LOCUS       DAMKNB010000150         5207 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.156, whole genome shotgun sequence.
ACCESSION   DAMKNB010000150 DAMKNB010000000
VERSION     DAMKNB010000150.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5207)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5207)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5207
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.156"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            complement(629..2764)
                     /gene="rnr"
                     /locus_tag="PC494_003519"
     CDS             complement(629..2764)
                     /gene="rnr"
                     /locus_tag="PC494_003519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HDF3913971.1"
                     /translation="MIPGLKESLLGLINESAYNPLKKEELAEIFDIHSSEMPMFYNFL
                     NELEEDGYICFTKKGKIVSPNQMGYFVGKFVSHKKGFGFVESDVEYTQDLFISSDNIN
                     GAMHNDRVMAEIVVPATEEKRAEGRIVKVIKREITRIVGTFQSSKTFGFVTPDNKKFT
                     KDIYIPKKHFSGAVDNDKVVCEITVWPQEDRKPEGKIIEILGQKGERGVEIDSIIREH
                     GLPEEFPKKVLQEAEAVAVEIPQEEIKRRRDLRDLNIFTIDGDDAKDLDDAISIEVLP
                     NGNFKLGVHIADVTHYVREKNKLDKEALKRATSVYLVDKVIPMLPKTLSNGVCSLNPF
                     EDKLTLSIFMEIDHKGNVVKHEICESVINSKARMTYTEVSDILEKDDEKLKKTFEHVV
                     EDFKNAEILARILMSRREKRGAIDFNFPEAKIILNGKGEVVDIKPYERRISNKIIEEF
                     MLISNETIAEHFYWMGIPFVYRIHETPSLEKMEELSKFISTFGYIIKGDKEEVHPKAL
                     QGIIEKIKGKKEEGAISTIMLRSLKQAKYSPECSGHFGLAAKFYCHFTSPIRRYPDLQ
                     IHRIIKESLNNKISGKRQEQLTTIVDYASVQSSEKERKAELAERDVHDFYKALYMKDK
                     VGQEFEGVVSSVTSFGIFVELDNTIEGLIRLANMNDDYYIYDESSYSVLGERTKKSYK
                     IGDLVKIKVESVNVDFKEIDFEIVEKIEE"
     gene            3360..3974
                     /locus_tag="PC494_003520"
     CDS             3360..3974
                     /locus_tag="PC494_003520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HDF3913972.1"
                     /translation="MEEVIAKIITIENGFKEIENIAKKIVKNNDSKKCYYLSIYLYRS
                     EYYQVRELAVFILGFISVTISEALLFLKDNVSKDENWRVQEILAKSFDYYCSEVGYEK
                     ALPVIKEWLNSDSPNIKRAVTEGLRIWTSRDYFKSNPDVAISLLSSLKEDDSEYLRKS
                     VGNALRDISKKYPDLVKKELDSWDISNKKVEFVYKLASKCILAK"
     gene            3992..4354
                     /locus_tag="PC494_003521"
     CDS             3992..4354
                     /locus_tag="PC494_003521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF3913973.1"
                     /translation="MKLRDEYTCPLELTHDMIKGKWKSIILWRLRIGPTSLSKLEKEI
                     NGINQKMLLEQLKELIEFGLVDKKTYEGYPLKVEYSLTPIRGKQILDALAIMQDIGIS
                     FMLDNGMEDILKEKGVLK"
     gene            4460..4957
                     /locus_tag="PC494_003522"
     CDS             4460..4957
                     /locus_tag="PC494_003522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbhB/YbcL family Raf kinase inhibitor-like
                     protein"
                     /protein_id="HDF3913974.1"
                     /translation="MKVTSTGIVNGVIEDKYGKRGTQFNEGGMPTYSLPLKFEDAPKN
                     TVSFAVFLEDKDSVPVCGFAWIHWLAVNITKDELNENESVTATDFVQGTTSWHGKLGG
                     LDRLEASVYGGMAPPDRPHVYEIHVFALDTILDLEKGFYMNEFFKAIEGHVLDTFTLK
                     GSYSN"
BASE COUNT         1693 a          796 c          617 g         2101 t
ORIGIN      
        1 aatgtttctc aattacttat ttttcaatta gccacttcta ttaagcattt cttaattact
       61 tatttttcaa ttagtcactt ctattaaaca tttcttaatt atttattttt caattagcca
      121 cttctattaa gcatttctta attatttatt tttcaattag ccacttctat taagcatttc
      181 ttaattactt atttttcaat tagccacttc tattaagcat ttctcaatta cttatttttc
      241 aattagccac ttctattaag catttctcaa ttacttattt ttcaattagc cacttctatt
      301 aagcatttct taattactta tttttcaatt agccacttct attaaacatt tcttaattat
      361 ttatttttca gttggctttt tctattaaat gtttcttaat tacttatctt tcagttagct
      421 ctttctatta aacatttctc aattacttat ttttcaatta gctactttca ttaaatattt
      481 cttaattatt tatctttcag ttaactattt ccattagata tttctcaatt acctattttt
      541 atcatttatt ttatagagta ttgtgcacta tatatttata catatcataa atactacaac
      601 ttgttatctc ttattttagc tgttttatct actcctctat tttttcaact atctcaaagt
      661 caatttcttt aaaatctaca ttaacacttt caacctttat cttaacaagg tctcctatct
      721 tatatgactt cttagttctt tctcctaaaa cactataaga actctcatca taaatatagt
      781 aatcatcatt catatttgca agtcttatca atccttctat agtattatct aactcaacaa
      841 atattccaaa tgaagttacg ctagatacaa caccctcaaa ttcttgacca actttatcct
      901 tcatataaag agccttatag aaatcatgta catctctttc agctaactct gcctttcttt
      961 ctttctcgga tgattgaaca gatgcataat ccactatagt agtaagctgt tcttgtcttt
     1021 ttccacttat tttattattt aaagattctt ttattattct atgaatttga aggtcaggat
     1081 atcttcttat tggtgaagta aagtgacagt agaatttagc tgctaatcca aaatgtccac
     1141 tacattctgg tgagtactta gcttgtttta aagaacgaag cattatagta ctgatagctc
     1201 cttcttcttt tttgcccttt attttctcta ttataccttg taatgctttt ggatgtactt
     1261 cctctttatc accttttatt atatatccaa atgtagatat aaacttactc aattcttcca
     1321 ttttttccaa agatggtgtc tcatgtattc tatacacaaa cggtattccc atccagtaaa
     1381 aatgttcggc aattgtctca ttacttataa gcataaattc ttctattatc ttattagata
     1441 ttcttctttc atatggcttt atatctacaa cttcgccttt tccatttaga attatctttg
     1501 cctctggaaa attgaagtct atagctcctc ttttttccct tcttgacata agaatcctag
     1561 ctaaaatttc agcattttta aaatcttcaa caacatgttc aaaagtcttt ttaagttttt
     1621 catcatcttt ttctaatata tcagatactt ctgtataagt cattctagct tttgaattta
     1681 ttacagattc acatatttca tgtttaacca catttccttt atggtctatt tccataaata
     1741 tagaaagagt taacttatct tcaaatggat ttaagctaca tactccattt gaaagagttt
     1801 ttggcaacat tggaattact ttatctacta aataaactga tgtagctctt tttaaggctt
     1861 ccttgtcaag tttatttttc tctcttacat aatgtgtaac atcagctatg tgaactccta
     1921 gtttgaagtt tccattaggt aatacttcta ttgatatggc atcatctaag tcttttgcgt
     1981 catctccatc tatagtaaat atgtttaaat ctcttaaatc tcttcttctt tttatctctt
     2041 cttgaggaat ctcaacagct acagcttctg cttcttgcaa tactttcttt ggaaattctt
     2101 ctggaagacc atgttctctt attatagaat ctatttctac gcctctttca cctttttgac
     2161 ctagtatctc tataattttg ccttccggtt ttctatcctc ttgtggccat actgtaattt
     2221 cacatactac cttatcatta tctactgctc cactaaaatg ttttttaggt atatatatat
     2281 ctttagtaaa tttcttgttg tctggtgtta caaatccaaa agttttactt gattggaagg
     2341 tacctactat tctagttatt tctctcttta ttacttttac tattcttcct tctgctctct
     2401 tttcttcagt tgcaggtact actatttctg ccataactct atcattatgc atagcaccat
     2461 ttatattgtc acttgagata aataaatcct gtgtatattc aacatcagat tctacaaatc
     2521 caaaaccctt tttgtgtgat acaaattttc caacaaagta tcccatttga ttgggagata
     2581 ctatttttcc ttttttagta aagcagatat aaccatcttc ttctaattca tttaaaaaat
     2641 tataaaacat tggcatttct gatgaatgta tatcaaatat ttctgctaat tcttcttttt
     2701 ttagaggatt atatgcactt tcatttatta atcctagcaa actttcttta agtcctggta
     2761 tcatttttcc ctcctgtttt acttttcatt atattattat ttatattgtc ttttatattt
     2821 cttcagacaa aacatttttt acttatcaca taattttcta tatttcctta ttattattac
     2881 aagttaaaat tacttattta tatttttgat ttaatgtaag ctttgtcata ctaacttcaa
     2941 acaaattatt atgttttata aattatttgt aaatatcatt ataattactt aagttattct
     3001 ttatcataat tgcttaaatt actctttatc acctaattat acaccatcaa ataggattgg
     3061 taaaatattc atctcatata agtattacta tataataatt tattctatta gtatactcaa
     3121 atcatgtaaa atttatataa ctcaattaat tttttaaata caactttata atataaaact
     3181 tataataaaa gtaaatttat atgttaaatg aggttgattt tttattattt tttatttatg
     3241 ctagtactaa agacttgcaa acgttttttg acaagtcttt attttgtcta aattaaacaa
     3301 acttttttac aaataaatac ataaaattta aactaatcta tttattggag gagataaaat
     3361 tggaagaagt aattgcaaaa attattacta tagaaaatgg attcaaagaa attgaaaaca
     3421 ttgctaaaaa aattgtaaaa aataatgact caaaaaagtg ttattatcta tcaatctact
     3481 tatataggtc agaatattat caagtaagag aattggctgt gtttatactt ggttttatat
     3541 cagtaactat ttctgaagct ttgttatttt taaaagataa tgtgagtaaa gatgaaaact
     3601 ggagagtaca agaaatacta gctaaatcat ttgattatta ttgcagtgaa gtaggatatg
     3661 aaaaggctct tcctgttata aaagaatggc ttaattctga tagtccaaac ataaaaaggg
     3721 ctgtgacaga aggtcttcga atttggacta gtagagacta ttttaaatct aatcctgacg
     3781 ttgctatatc actactttct agtttaaaag aagatgatag cgaatacttg agaaagtctg
     3841 taggtaatgc tcttagagat ataagtaaaa aatatccaga tttagtaaaa aaagaattag
     3901 attcatggga tatatcaaat aaaaaagttg agtttgtata taagcttgct tcaaaatgta
     3961 tcttggcaaa gtaaaatgga ggtgaactta tttgaaactt cgtgatgagt atacttgccc
     4021 attagaacta acacatgata tgataaaagg caaatggaaa tctattatat tatggagatt
     4081 acgcatagga ccaacttcct tatcaaaact tgaaaaggaa atcaatggta ttaatcaaaa
     4141 gatgttactt gaacaactta aagaattaat tgaatttggt cttgtagata aaaagacata
     4201 tgaaggttac ccacttaaag tcgaatactc acttacacct attcgaggga aacaaatatt
     4261 ggatgctttg gctataatgc aagatatagg aattagcttt atgttggata atggtatgga
     4321 agatattctt aaggaaaaag gtgttttaaa gtaaatagat acccacaaaa aagtaagtaa
     4381 tttaccatta ttttcaactg gtatataatt aaattataga tatattctat taatttatta
     4441 taataggagg taaattatta tgaaagtaac tagtacaggt atagtaaatg gtgttataga
     4501 agataaatac ggtaaaagag gaactcagtt caatgaaggt ggtatgccta cctattcact
     4561 acctctaaag tttgaagatg ctccaaagaa tacagtatcc tttgctgtat ttttagaaga
     4621 taaagactct gttcctgtat gtgggtttgc atggatacat tggttagctg taaatataac
     4681 aaaagatgag ttaaatgaaa atgaaagtgt aacagctact gattttgtac aagggactac
     4741 tagttggcat ggtaaactag gaggtcttga cagattagag gccagtgtat atggtggaat
     4801 ggctcctcca gacagacctc atgtctatga aatacatgta tttgcacttg atactatcct
     4861 tgaccttgaa aaaggattct atatgaatga atttttcaaa gctattgaag ggcatgtttt
     4921 agatacattt acactaaaag gaagttattc taattaatta ggttgactat agctaatcat
     4981 taattaaatg ctacatttaa ttgatgatta gcttaattgt tattagaata ttttctgcac
     5041 tttatcttaa tatatatttt agttgactgg tattttaatt tatattagat tattatcaat
     5101 ttatataaat tgattttagc ttaaaactta cttatctatt tcagtttcta ttagaattat
     5161 tattagactc attaaaataa aagcattaat ataactaata atatatg
//
LOCUS       DAMKNB010000151         5195 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.157, whole genome shotgun sequence.
ACCESSION   DAMKNB010000151 DAMKNB010000000
VERSION     DAMKNB010000151.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5195)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5195)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5195
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.157"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            complement(26..562)
                     /locus_tag="PC494_003523"
     CDS             complement(26..562)
                     /locus_tag="PC494_003523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HDF3913975.1"
                     /translation="MIKETHERGGYIFALLILPFINNLYLVKYDIAYKIVLIIIYIYF
                     AYLGSLFPDIDMRGSYISKKFMLIYKLFGSRFRHRGFTHSLIALLLIYSFFKSLTIFT
                     NNNIVFSCLSSGFIIGYLSHLCLDLITKEGIELFYPITINISLLPIKTNSKTEKFISK
                     LLNFIVIFLIGYQFYILL"
     gene            complement(675..1349)
                     /locus_tag="PC494_003524"
     CDS             complement(675..1349)
                     /locus_tag="PC494_003524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000094049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HDF3913976.1"
                     /translation="MSLFIISQCITSFAFTPENNKFKVKPLPYAYDALEPYIDKETMK
                     LHHDKHYQAYVDKLNAALEKYPELYNYSLCELLQNLDSLPKDIATTVRNNAGGAYNHK
                     FFFDIMTPEKTIPSESLKEAIDRDFGSFEKFKQEFQKSALDVFGSGWAWLVATKDGKL
                     SIMTTPNQDSPVSKNLTPIIGLDVWEHAYYLKYQNRRKEYIDNWFNVVNWNGALENYK
                     NLKSQD"
     gene            1552..3426
                     /gene="asnB"
                     /locus_tag="PC494_003525"
     CDS             1552..3426
                     /gene="asnB"
                     /locus_tag="PC494_003525"
                     /EC_number="6.3.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase (glutamine-hydrolyzing)"
                     /protein_id="HDF3913977.1"
                     /translation="MDGNISIYYKGDISKKEDIKFKIKESVNNTRLSSRIEYKDEEKT
                     FDFERFNVIDAIYGNKPFEKDGKVIVFNGNIYNYHEIKEELIKKGHNFTTNDDIEVLL
                     ASYIEFGKNCVHKIKGMFNFIIYDRENESIFGARDLFGIKPLYYINKENAIIFSSEYK
                     FLLEYMKNLNINERSLQSYFSFQYVLPEDTMIQGIRLIPAGHYFRVENGILSLKRYNK
                     LEFRSSTKFFYTKNHLGNRDVNEDDIRNIVVDSIVTHMEEEKEIGTFLSGGIDSSIIT
                     TVASQINPNIKSFSAGFSVKGYSELEVAKKTADKLGIENIQINITQDEYIKSLPNVIY
                     SLDDPIADPSEVGLYFLIKEAGKHVKVALSGEGADELFGGYNIYKEYSTMKSVVNSPT
                     YIKSILGRVSELMPNIKGRNYLYRATTPLEKRYIGNAKVFENSEVKRFFFKYKEKNIY
                     EYLLSNLYRDAQKNNYDYISKMQHIDVNTWLQGDILQKISKLSTAEQVELRVPFLYKD
                     VFDVAKNLRMEQKINKNNTKVLLREAFREIVPEHVVQRKKLGFPTPIRVWLKDSLGDI
                     VKETIYNSNVDEFIDKKYAIKLLDTHLKGHRDNSRKIWTIFTFCLWHQLFIEHKNVEY
                     "
     gene            complement(3518..4954)
                     /locus_tag="PC494_003526"
     CDS             complement(3518..4954)
                     /locus_tag="PC494_003526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HDF3913978.1"
                     /translation="MICTIKPLKISIKKSTEPLIEFISDTTYKNKSSSYIKEVYFTRY
                     IGVDDSIDKYIEKIKNIDTYFFNNPTIPYIRLNNLKINFDKEQTDKMLKIFNIYNSSK
                     FNSWDLYNIDFPCKIENDTLNWTKKIAFKNTLDLFSTSMPNCTSSIIKNFAVKLLCWI
                     DYFLPKLFYNKVKTTISPKIVYFGNIKRQELFFLYFLSQLGCDILYINPNKDILDLYP
                     ECSKFSTLFELSRKTPNILEIPFERHITNINYSENTNKTSPTTNKPNSKNTLNNTNLT
                     SKKIVQDEEVELSYEDLAKLSASVVMIVVCNNENKPFKSGSGVVINNEGYILTNLHVV
                     NDGYSFLVRFENDDKVYTSYQIIKYHSDYDLAVIKVDRKCKPIPVKVSKKPVRGQKIV
                     AIGSPLGLFNTVSDGIISAFRDFETVQMIQFTAPISSGSSGGALLDMFGNLLGLISAG
                     YDDGQNLNLAVESSLVKIFANNFIEIVN"
BASE COUNT         2009 a          621 c          744 g         1821 t
ORIGIN      
        1 atattgttat ttattttttc tacaactata ataaaatata aaattgatat ccaatcaaaa
       61 aaataactat gaaatttaat agcttagata tgaatttttc tgtttttgag ttagttttta
      121 taggtagtaa agaaatgttt atggtaatgg gataaaacaa ttcaatacct tctttagtaa
      181 taaggtcaag acacaagtga gatagatatc ctattataaa cccactggac aaacatgaga
      241 aaactatatt attgttagtg aagattgtca gagatttaaa aaaactataa ataagtaata
      301 aggcaattag actgtgagta aaccctctat gtctaaacct acttccaaat aatttgtata
      361 ttaacataaa ttttttactt atgtaagaac ctctcatatc tatatctgga aataaagaac
      421 ctaaatatgc aaaataaata taaattataa ttaatactat tttatatgca atatcgtatt
      481 taactaggta cagattgttt ataaagggga gtatcaaaag tgcgaatata taacctcccc
      541 tttcatgtgt ttcttttatc atataaaaat cctcctgaat cgtcactata aacattatat
      601 tggtaaattt agactatctt ttattatatt atatagcaaa cataagtttt tttcaaaagg
      661 attttaatat ttaattaatc ttgagatttt aaatttttgt aattttctaa agcaccattc
      721 caatttacta cattaaacca gttgtcaatg tattcttttc ttctattttg atattttaaa
      781 tagtaagcat gctcccaaac atcaagtcct attataggag ttaggttttt acttacaggg
      841 ctatcctgat ttggagtagt cataatagat aatttcccat ctttagtagc tacaagccaa
      901 gcccaaccag aaccaaagac atctaaagca gatttttgga actcttgctt aaatttttca
      961 aaagaaccaa agtctctatc aatagcttct tttaaagatt cagaaggtat ggttttttct
     1021 ggcgtcatta tatcaaaaaa gaatttatga ttataagctc cacctgcatt atttcttaca
     1081 gttgtagcaa tatctttagg taaagaatct aaattttgca ataattcaca taaagaataa
     1141 ttataaagct caggatattt ttcaagagca gcatttaatt tatcaacata agcttgataa
     1201 tgcttatcat gatgcagttt cattgtttct ttatctatat aaggttcaag tgcatcatat
     1261 gcataaggta atggtttaac cttaaatttg ttattttcag gtgtaaaagc aaatgaagtt
     1321 atgcactgtg agattataaa taaagacata ataactggta ttaatatttt tttcttcata
     1381 aaaatcacct cctaatatag tatttctaga aataaaaaaa atatgaaata ttaacagata
     1441 atttataaga atttaatagc aatttcattt taaattgaat aagttttaaa gccaaagaca
     1501 aaactatgaa atatagaata agactaaagg acagaaagga attttgatta tatggacggc
     1561 aatatttcaa tttattataa aggtgatata tctaaaaaag aagatattaa atttaaaata
     1621 aaagaatctg taaataatac aagactttct agtagaatag agtataagga tgaggaaaaa
     1681 acttttgatt ttgaaagatt taatgtaatt gatgctattt atggaaataa accatttgaa
     1741 aaagatggaa aagttattgt ttttaatgga aatatatata actatcatga aataaaagaa
     1801 gaattaatta aaaaaggaca caattttact acaaatgatg atattgaagt cttattagca
     1861 tcttatatag aatttggtaa gaattgtgta cataagatta aaggaatgtt caactttata
     1921 atctatgata gagaaaatga aagtatattt ggagcaagag atttatttgg gataaaacca
     1981 ctttattata taaataagga aaatgcaata attttttcct cagagtataa gtttttactt
     2041 gaatatatga aaaatttaaa tataaatgaa agaagcttac aaagttattt ttcatttcaa
     2101 tatgtacttc ctgaagatac tatgatacaa ggaataaggc tgataccagc aggtcactat
     2161 tttagggtag aaaatggtat actatcttta aagagatata ataaacttga gtttagaagt
     2221 agtacaaaat ttttttatac taaaaatcac ttaggcaata gagatgtgaa tgaggatgat
     2281 ataagaaata tagtagtaga ttcaatagta actcatatgg aagaggagaa agaaattgga
     2341 acatttttgt ctggtggaat agattcatct attataacta ctgtggcttc acaaattaat
     2401 ccaaatataa aatctttttc tgcaggcttt agtgtcaaag gatatagtga attagaagta
     2461 gcaaagaaaa cagctgataa gttaggtata gaaaatatcc agattaatat aacacaagat
     2521 gaatatataa aatcattacc gaatgtaatt tattctttgg atgaccctat agcagaccct
     2581 tcagaagtag gtctttattt cttaattaaa gaggcaggta aacatgttaa agtagcattg
     2641 tctggagaag gagcagatga attatttgga ggatataata tatataaaga gtatagtact
     2701 atgaaatcag ttgtcaattc acctacttat attaaaagta tattaggaag agtttcagaa
     2761 cttatgccaa acataaaagg aagaaattat ctttatagag ctacaacacc attagaaaaa
     2821 agatatatag gaaatgcaaa agtttttgaa aacagcgaag taaaaagatt cttttttaag
     2881 tataaggaaa agaatatata tgaatacctg ttgtctaatt tgtatagaga tgcacaaaaa
     2941 aataattacg attatataag taaaatgcaa catatagatg tgaatacatg gcttcaaggc
     3001 gatatacttc aaaaaattag caaactttct acagctgagc aggttgaact tagagtacca
     3061 tttttatata aagatgtatt tgatgtcgca aaaaatttaa gaatggagca aaaaataaat
     3121 aagaataata caaaagtttt acttagagag gcgtttagag aaatagtccc agaacatgtt
     3181 gttcaaagga aaaaattagg atttccaact ccaataagag tttggttaaa agattctcta
     3241 ggggatattg taaaggaaac tatttataat tcaaatgtag atgaatttat agataaaaaa
     3301 tatgcaataa aacttttaga tacgcatctt aaaggtcata gagataattc gagaaaaata
     3361 tggactatat ttacattttg tctatggcat caattattta ttgagcataa aaatgtcgag
     3421 tattaatact tttttcaata ttaatcagag ggcaaaagca tgcaatgttt tcaccctctt
     3481 gattattatg gaataggata agtagaattt tgattgatta gtttactatc tcaataaaat
     3541 tattggcaaa tattttgaca agactacttt caacagctaa atttaagttt tgtccatcat
     3601 catatccagc ggaaatcaat cctagtaagt ttccaaacat atctaaaaga gctcctcctg
     3661 aactaccact agagattgga gctgtaaatt gtatcatttg aaccgtttca aaatcacgaa
     3721 aagctgaaat aattccatct gaaactgtat taaaaagacc tagagggctt ccaattgcaa
     3781 ctattttttg acctctcaca ggttttttac tgactttaac aggtattggc ttgcattttc
     3841 tatcaacctt tatcacagct aaatcataat ctgaatggta ttttataatt tggtaagatg
     3901 tataaacttt atcatcattt tcaaatctaa ctaaaaatga atacccatca ttgactacat
     3961 gaagattcgt aagtatataa ccttcattat ttattactac tccagaaccg ctcttaaacg
     4021 gtttattttc gttattgcac acaacaatca taacaacaga agctgataac tttgcaaggt
     4081 cttcataaga aagttctact tcctcatctt gtacaatttt tttagatgtt agatttgtgt
     4141 tattaagtgt atttttagag ttaggtttat tcgtagtagg agaagtctta ttggtatttt
     4201 cactgtaatt tatatttgta atatgccttt caaaaggtat ttctaatata tttggagtct
     4261 tcctagaaag ttcaaataga gtagaaaatt ttgaacattc aggatataaa tcaagaatat
     4321 ctttatttgg atttatatat aaaatatcac acccaagttg tgataaaaaa tataagaaaa
     4381 aaagttcttg ccttttaata tttccaaagt atactatctt tggtgaaata gtagtcttca
     4441 ccttgttata aaataattta ggtagaaaat agtctatcca acacaaaagt ttaactgcaa
     4501 agtttttgat gatagaggat gtacaatttg gcatacttgt ggaaaataaa tctaaagtat
     4561 ttttaaatgc aatcttttta gtccaattta aggtgtcatt ttctatttta catggaaagt
     4621 cgatattata taaatcccaa ctgttaaact tagaactatt ataaatatta aaaattttaa
     4681 gcatcttatc tgtttgttct ttgtcaaaat ttatttttag attgtttaat ctaatatagg
     4741 gaattgtagg attattaaaa aaataagtat ctatattttt aattttttct atgtatttat
     4801 caattgaatc atcaacacct atatatcttg taaagtagac ttctttaata tatgaagaac
     4861 tcttattttt ataggtagta tcagatataa attcaattag aggttcagta gactttttta
     4921 ttgaaatctt taatggttta atagtacaaa tcatattttt tctcctataa taagatgata
     4981 taatctatta taaaacaact taaaacaata tagtacaata attttgtagt ttcaaaataa
     5041 aatatgtact tgtttatata aatgatatat aattacaata aaattgccga aaagccctct
     5101 cctttaggtg tagggatgaa aggtaaggtc ttaatataaa aaaagttaga ataatgcttg
     5161 taatctaata ccgctactga taccctatat ttagg
//
LOCUS       DAMKNB010000152         4881 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.158, whole genome shotgun sequence.
ACCESSION   DAMKNB010000152 DAMKNB010000000
VERSION     DAMKNB010000152.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4881)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4881)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4881
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.158"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            complement(502..1143)
                     /locus_tag="PC494_003527"
     CDS             complement(502..1143)
                     /locus_tag="PC494_003527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase"
                     /protein_id="HDF3913979.1"
                     /translation="MNNNFQDNQTINLIQSRRSIRKFTTEQISDEQVNTLLHCAFAAP
                     SGCNKQPWHITVVQDQKLLKEISDDTLSRIHEVSNVEINKNFKLFYGAPTVLFISYDE
                     SSSWAPYDIGILTGNITTAAQALGLGSCIIGMVRGLFTPVEQGDIEGLVSVLDKEDVK
                     ESESIKMKFDTNKKYRELLDIPEGYSVPFGIAVGIPDGNLPNAREVVYKVSRV"
     gene            complement(1386..2189)
                     /locus_tag="PC494_003528"
     CDS             complement(1386..2189)
                     /locus_tag="PC494_003528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HDF3913980.1"
                     /translation="MNKKGFTLIELLVVISIIGILVIVAVPALFRNIEKSKAVTCLSN
                     RENIKTQIVIAMAEESSKGKNEVMKEVLENKDGKYFETEPKCKSGGIYSATFDDGYDG
                     ITGIESIAKVYVTCTKHPDGVEMARDIHQSMKDLIASFAQDPSIIPGASKGNDDFRKY
                     LLDNKYKNGWPTIPDEFKAKYGLSKDTLYIQPYAYSPTKSDATVVVFANNKTGGNWYT
                     SLVYDYDEGRWYKGKNGISVAGRSWDVDTDSVKSVKTEIHSKEGWGPLN"
     gene            complement(2345..3520)
                     /gene="thiI"
                     /locus_tag="PC494_003529"
     CDS             complement(2345..3520)
                     /gene="thiI"
                     /locus_tag="PC494_003529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HDF3913981.1"
                     /translation="MVYNILIVKYGEIGVKGKNRYIFENRLIRNIRNMLKPIGRFNVY
                     KEYGRIYVDLEDYDYEEVIEEVRKVFGIVGVCPGVRAKKDYDTLKEIALKMLEEKIEA
                     GYKTFKVESRRGDKSFGLTSQEMSMDIGGYLLSKVGDRINVDVRNPEVKIKCEYREFH
                     TMVYSDTIPGYGGLPLGTNGRAMSLLSGGIDSPVATWMVAKRGMEVEAVHFHSYPFTS
                     ERSQEKVKDLAKILAKYCGRVRLHKVNILEIQKAIGENCNEEEATILSRRFMMRIAQR
                     LSEKRHCDALITGESIGQVASQTIQGLTCTNAVVDLPVFRPLIAMDKSDIVDIAKKIG
                     TFETSILPEEDCCSVFSPRKPVTKPRLEKIEKSETALDIEKLVQDAIDKIEVEDIEF"
     gene            complement(3566..4717)
                     /locus_tag="PC494_003530"
     CDS             complement(3566..4717)
                     /locus_tag="PC494_003530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HDF3913982.1"
                     /translation="MEIYLDNSATTKPYQEVIDKMVYALNTEYGNPSSVHRKGVEVEK
                     AIKEVRQDIAKSLGAKEKEIYFTSGGTECNNTIIRGITSLNKKRKNHIISTNIEHPSV
                     LNTLKDLEEDGFEVTYLEVGKDGKINIEDLKNAIKSTTCLVSMMHVNNEIGTIQPIGE
                     VGKYLKGLKEKIYFHVDAIQSYGKINFRPSKYNIDFMSVSAHKFHGPKGIGFMYIKEN
                     NRLKPMLTGGGQEIGIRSGTENVPGIYGLGEAVRILNKDLDAVISKVNNLKNILKNEI
                     IDNIEDIKINSPEDGVCHILNVSFRGTKGEVLLHYLEQKGIYVSTGSACSSKKKGSYV
                     LNAIGLTNEEINGTIRFSLSDMNTEEEMLEAVKVLKESICDLRSIMKRK"
BASE COUNT         1514 a          929 c          467 g         1971 t
ORIGIN      
        1 taaatttatg aacatttttt gtttttatgt taggatattt cttagaaatg aaatacttct
       61 taatttgatt tgatatgtat atttttatag ctattttatt ataaaaaaaa agaacccttt
      121 tataactaag ggttactttt tttctctatt ttttcttatt atatcactat tttttcccta
      181 tttcaatatt ttgacatttt ttccattata ctgaaaagat atcttaaatt tttaacttgg
      241 ataaatttta aatcatatac ttaaaattaa catacttgtt ttctatttta ttacacttaa
      301 tccttatttt tatcattcta caaaacaaaa ataaaaaaga ataagataat aaataaaata
      361 cttatcacct tattctttat ttaattattt tacaacgaaa aatctaaact actttttaaa
      421 tagcttcctc ttccatcaat ttatttgtat attactggtt taattcttca agtaactgat
      481 tggttcttgc aatactttat cctaaactct ggaaactttg taaactacct ctctagcatt
      541 tggtaaattt ccatctggaa tacctacagc aataccaaat ggtacagaat acccttctgg
      601 tatatcaagt agttctctgt attttttatt tgtatcaaac ttcatcttta ttgactctga
      661 ttcttttaca tcttctttat ccaatacact cacaagacct tcaatatccc cttgttcaac
      721 aggtgtaaat aaacctctaa ccattcctat tatacaactt ccaagcccta gtgcttgtgc
      781 agctgttgtt atattccctg taagtattcc tatatcatat ggagcccatg aactactttc
      841 atcataagaa ataaataaaa cggttggagc accataaaat aacttaaagt ttttatttat
      901 ctcaacatta ctcacctcat gaatcctaga taaagtatca tcactaatct cttttaaaag
      961 tttctggtct tgcacaacag ttatgtgcca aggctgttta ttacatcctg aaggtgctgc
     1021 aaatgcacag tgtaataatg tgtttacttg ctcatcacta atttgttctg tcgtaaattt
     1081 tcgtatactt ctacgacttt gtattaaatt tattgtttgg ttgtcttgaa aattattatt
     1141 catatctatt ccccttttta tgtatttctt agtacaaata ctaaatcttc agaaaattaa
     1201 tcttataatt aaatttcttt acaatattat tataattatt tttagcttgt atgtgaagac
     1261 ttaaaaatat aaacactttt aatatatctc aattatatat ataaatgaaa atctggtatt
     1321 cgtcatctat agaaactgct cttttctata gtttaatcaa taccagatta ataaaacatg
     1381 atatattaat ttaaaggacc ccatccctct ttagaatgaa tctctgtttt tacagactta
     1441 acactatctg tgtcaacatc ccatgaccta cctgcaacag aaataccatt tttaccttta
     1501 taccatctac cttcatcata atcgtaaact agggaagtat accaattacc cccagtctta
     1561 ttatttgcaa atacaactac agtagcatca gatttagtag gactatatgc atatggttgt
     1621 atatatagtg tatccttact taatccatat tttgccttaa attcatctgg aattgtaggc
     1681 cacccatttt tatatttatt gtctaataaa tattttctaa aatcatcatt accctttgaa
     1741 gctcctggta ttatagaagg gtcttgtgca aatgatgcaa tcaaatcttt catactttga
     1801 tgtatatccc tagccatttc aacaccgtct ggatgttttg tacaagtaac atacactttt
     1861 gcaatgcttt ctattccagt tattccatca taaccatcat caaacgttgc tgaatatatt
     1921 ccacctgact tacactttgg ttctgtttca aagtacttac catctttgtt ttctaatacc
     1981 tctttcatga cttcattctt gcctttactt gattcctcag ccattgcaat aacaatttga
     2041 gtctttatat tttctctatt agaaagacat gtaactgctt tacttttttc tatatttcta
     2101 aacaatgctg gaacagctac tataactaaa atgcctatta tagatataac tactaacaat
     2161 tcaattagtg taaaaccctt tttattcata ataatcattc ccattaaata aaattatagt
     2221 acttattttt aaatactaca tattaataaa ttgtctacat aaatcctttc aacagaacta
     2281 ctaatatact tacagaacta ctaatatact caatattcaa tttagtaatt aaataacttg
     2341 tatgctaaaa ctcaatatcc tctacctcta ttttgtcaat agcatcctgt actaattttt
     2401 caatgtcaag tgctgtttca gatttttcta ttttctctaa tctaggttta gtgacgggct
     2461 ttctaggaga aaatacacta caacaatctt cttcaggcaa tatagatgtt tcaaaagtcc
     2521 ctattttttt ggctatatca actatatctg atttatccat tgctataagt ggtctaaaca
     2581 ctggtaagtc tacaacggca ttagtacaag taagtccttg tatagtttga gatgcaacct
     2641 gcccaatact ttcacctgta attaaagcat cacaatgtct tttttcagaa agtctctgtg
     2701 ctatcctcat cataaatctt cttgaaagaa tagtagcttc ttcttcatta caattctcgc
     2761 caattgcttt ttgtatttct aagatattaa ctttatgaag ccttactcta ccacagtatt
     2821 ttgccagtat tttagctaaa tccttaactt tttcctgtga cctttcactt gtaaatggat
     2881 aactatgaaa gtgaactgcc tctacttcca tacctctttt tgcaaccatc catgtagcta
     2941 ctgggctatc tatacctcct gataaaagag acatagctct accattcgtt ccaagtggca
     3001 atccaccata tccaggtata gtatcactat agaccatagt atgaaattct ctgtattcgc
     3061 actttatttt aacttctgga tttcttacat caacattaat cctatctcct acctttgata
     3121 ataagtatcc acctatatcc atactcattt cttgagaagt caacccgaaa gacttatctc
     3181 ctcttcttga ctctacctta aaagttttat atccagcctc tattttttct tctaacattt
     3241 ttaaagctat ttcttttaat gtatcataat cttttttagc tcttactcca gggcacacac
     3301 ccactatccc aaatactttt ctaacttctt caattacttc ttcataatca tagtcttcta
     3361 aatcaacata tattcttcca tactctttat atacattaaa tcttccaatt ggttttaaca
     3421 tatttcttat atttcttata agcctattct caaatatata tctattcttt ccttttactc
     3481 caatttctcc atactttact attaatatat tatacaccat ttcacctctt aaactaattt
     3541 attatcacta tctatacagt attctttatt ttcttttcat tattgacctt aagtcacaaa
     3601 ttgattcttt caaaactttc acagcttcta acatttcttc ttctgtattc atatcagata
     3661 aactaaatct tattgttcca tttatttctt catttgtaag acctatagca tttaatacgt
     3721 aactaccttt ctttttagaa gaacatgcag agccagttga tacataaata cctttttgct
     3781 ctaagtaatg aagtaaaact tctccttttg tccctctaaa tgatacattt aatatatgac
     3841 atactccatc ttctggagaa ttaattttta tatcttctat attatcaatt atttcatttt
     3901 ttaatatatt ttttaagtta tttactttcg aaataacagc atctaaatct ttgtttagta
     3961 ttctaacagc ttctccaaga ccatatattc caggtacatt ttctgttccc gacctaattc
     4021 caatttcctg accaccacct gttaacatag gcttaaggcg attattttct tttatataca
     4081 taaatccaat tccctttgga ccatgaaatt tatgtgcact tacactcata aaatctatat
     4141 tgtatttaga tggtctaaag ttaatttttc catatgactg aatagcatca acatggaaat
     4201 aaattttttc ttttaaaccc ttcaaatact ttccaacttc acctattggc tgtatagttc
     4261 ctatttcatt gttaacatgc atcatgctta ctaagcatgt agttgacttt atcgcatttt
     4321 ttaaatcctc tatatttatt ttcccatctt ttccgacctc taaataagtt acttcaaaac
     4381 catcttcttc taaatctttt aatgtattta aaacagaagg atgttctatg ttagtagata
     4441 ttatgtgatt ttttcttttt ttatttaaac tagtaatacc tcttattata gtattattac
     4501 actctgtacc acctgatgta aaataaatct ccttttcttt cgctcctaga gatttagcta
     4561 tatcttgtct tacttctttt atagcttttt caacttctac accttttcta tggacagaag
     4621 aaggatttcc atattccgta ttaagtgcat aaaccatttt atctataact tcttgataag
     4681 gttttgtagt tgcgctattg tctaagtata tttccaactt aattacacct acctttattt
     4741 aaaatcttca actctaacta ttataccact aattatagta ttttttttgt taatctttat
     4801 taaaaagaca atcttaaatt ataaaatatt atttcatgaa aagctagttt tttcacttta
     4861 ttacaaattt ttatagtaaa a
//
LOCUS       DAMKNB010000153         4824 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.159, whole genome shotgun sequence.
ACCESSION   DAMKNB010000153 DAMKNB010000000
VERSION     DAMKNB010000153.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4824)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4824)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4824
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.159"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            complement(58..495)
                     /locus_tag="PC494_003531"
     CDS             complement(58..495)
                     /locus_tag="PC494_003531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LytTR family transcriptional regulator
                     DNA-binding domain-containing protein"
                     /protein_id="HDF3913983.1"
                     /translation="MKIHVEQGINCDDIEITIKCSALDNNIEKIISLLSTPLLDIKGK
                     KSGEIYKLNVCDILYFETVGNKTFAYYEDDVFEIDLKIYKLSKLLANTSFSRISKSMI
                     LNMDYIKSIKVISHNRMQATLKNNEKVIINRRYIKNIKEKLNI"
     gene            complement(752..901)
                     /locus_tag="PC494_003532"
     CDS             complement(752..901)
                     /locus_tag="PC494_003532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvrJ family protein"
                     /protein_id="HDF3913984.1"
                     /translation="MDDSLQLLITNVGFPIALSMYLLVRIEGKLNTLSNSIDTLSKNI
                     LIFKK"
     gene            complement(914..1144)
                     /locus_tag="PC494_003533"
     CDS             complement(914..1144)
                     /locus_tag="PC494_003533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2922 domain-containing protein"
                     /protein_id="HDF3913985.1"
                     /translation="MEIKKKLVMSFKNVKDKQVSFSIENPKDDLTEENIKSVMDLIVS
                     KNIFSVGGFDLASVVEAKVVETNTTPYDLVIE"
     gene            complement(1962..2183)
                     /locus_tag="PC494_003534"
     CDS             complement(1962..2183)
                     /locus_tag="PC494_003534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1659 domain-containing protein"
                     /protein_id="HDF3913986.1"
                     /translation="MEVVSTKNLSSIKLKLDAGFDDKGKAVVKSKSFANVKAEALNED
                     VYAVAEAIASLQENPIVDILKLDSTSLSK"
     gene            2763..3020
                     /locus_tag="PC494_003535"
     CDS             2763..3020
                     /locus_tag="PC494_003535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HDF3913987.1"
                     /translation="MKIKVEDIPVQFHAMVEIIGIDKFIEVAKLYGGTNTYIPTYKGL
                     FRYARNRDIVKQFNGVNHNELAIRYNMCVSNIKRILNENNV"
     gene            3489..4727
                     /locus_tag="PC494_003536"
     CDS             3489..4727
                     /locus_tag="PC494_003536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conserved phage C-terminal domain-containing
                     protein"
                     /protein_id="HDF3913988.1"
                     /translation="MNKGFYKLNSVVLNFDIKNDVNKIRFNHYIMRKENIQRLQGTLP
                     NGQFYMTVRRAATDLQLSISTISRLVKEFLDLGIIRLVSKGVKGNRSVYSYVSIEFNG
                     SLFDDSKYMELDCVCNDEFIDNSGIEFDCDSKDNSFNGDINVETVHCINEYLSDDDVE
                     HNYNNFHNKDTIKDKAISNISTIKKYIDESFDKNKSENSNLQQESINFNFNDTCNEID
                     KRTNNSIENNQNKRPMRLSDISVLSDKGMTNKKNYFNHNHGIQKGTKSVTKKKESLNK
                     FNKKNIQQSIINMLNKKSGKNFKIDSPISIKLINERLKEGYVLEDFYKVIEVKVAKWK
                     NTIMEMYIRPETLFSYKFESYVNENISMKSQSNVHPCKEGNSNDSSNYIHSDYTTYDG
                     SVRERKKYENVRYWNPICEI"
BASE COUNT         1845 a          484 c          676 g         1819 t
ORIGIN      
        1 ttaaataggt caataaattt gcaattagtg atattaataa attactttag atttttatta
       61 aatgtttagc ttttctttaa tattttttat ataacgacga tttataataa ctttttcgtt
      121 gttttttaaa gtagcttgca tgcgattatg tgatattact tttatacttt ttatgtagtc
      181 catatttaaa atcatggatt tagatattcg tgagaaggat gtattagcta ataattttga
      241 taatttatat atttttaaat caatttcaaa tacatcatct tcataataag caaatgtttt
      301 atttccaact gtctcaaagt ataaaatatc acagacattg agtttataaa tctctcctga
      361 ttttttacct tttatatcaa gtaacggtgt actcaataat gaaattattt tttcaatgtt
      421 attatctaga gcagaacatt ttatggttat ttcaatatca tcacaattaa taccttgttc
      481 gacatgtatt ttcattaatc atcacctcat tttattactg tcattagaat agcattatat
      541 cttattgagt ccaactagat gcgttctaaa tttcaaatta agcatagtga aattcaaaaa
      601 taaaacagtg aaattcaaat ttgaggtggt aaaattcaaa aaaatactat ggatatttgg
      661 ataaattatc caaatatcct agtatttcac atagaatatg tctaattatt ttacaaatag
      721 acctatttta tgacttacat atattgtcaa attacttctt aaatatcaaa atatttttgg
      781 ataatgtatc aatactgttt gataaagtat ttaatttacc ctcaattcta accaataagt
      841 acatggatag agctatagga aaaccaacat tggttattaa cagttgtaaa ctatcatcca
      901 taaaattagc cccctattct ataactaagt cataaggagt ggtatttgtt tccacaacct
      961 tggcttcaac aacagaagct aggtcaaatc ctccaaccga aaaaatattt ttagatacta
     1021 tcaaatccat gacagatttt atattttctt cagttaaatc atcctttgga ttttctatag
     1081 aaaaagaaac ttgtttatcc tttacatttt taaagctcat gactaatttt ttcttaattt
     1141 ccatataatt acctccgata taataattta tattttaatt gtttgcttgt taatattggt
     1201 attttaattg tcaatattaa tgttttgctt gttagtatta atatttcaat tgtcaatatt
     1261 aatgttttgc ttgttagtat taatatttca attgtcaata ttagtgtctt gcttgttagt
     1321 attaatattt caattgtcaa tattaatgtt ttgcttgtta gtatcagtgt ttcaattgtc
     1381 aatattagtg ttttgcttgt tagtattaat atttcaattg tcaatattag tgtcttgctt
     1441 gttagtatta gtatttcaat tgtcaatatt agtgttttgc ttgttagtat tagtatttca
     1501 attgtcaata ttagtgtttt gcttgttagt attagtattt caattgtcaa tattaatgtt
     1561 ttgcttgtta gtattagtat ttcaattgtc aatattagtg ttttgcttgt tagtattaat
     1621 atttcaattg tcaatattag tgttttgctt gttagtatca gtgtttcaat tgtcaatatt
     1681 agtattttaa ttgttgactc tagttattgc tgatatagaa aatatttaat ttatttcaat
     1741 taattagatt aaagtagggt agcatctaaa atagctaaca tgtttaagtt gaaatacgtt
     1801 taatatatta atttttcaaa gcattaatat attaaagtta taatcaaaat tgaagttata
     1861 atctgccaaa tctatagcgt attaagtgcg ttatataact taatctttta tataaagagt
     1921 taattttttt aatttgtaaa gcagagtacg tttaaaaggt actatttaga taatgatgta
     1981 ctatctaatt ttaaaatatc tacaataggg ttctcttgaa gacttgctat tgcttctgca
     2041 acagcataaa catcttcatt taatgcctct gcttttacat ttgcaaatga tttactttta
     2101 acaactgcct tacccttatc atcaaaacca gcatccaatt ttagttttat actagataaa
     2161 ttttttgttg aaacaacttc cataaaatta cctcctaaaa atttaatttc aaagatttgt
     2221 cgactttctt tgttagctat aatactatca tctaagataa tatcggagtt aaacagtaat
     2281 ttctaaagat tttttgtgta aatttttata ggaaaaattt tacttttttg ctgatgaaaa
     2341 agtttacaag ttatttgtga agatatgttc ttagtgtttt gaaatagtat ttgtatatat
     2401 tcatgcttag ttgagatagt tttgtatgga ttttcatatg tgtagagtta aatgttaggt
     2461 actaaagttt atgttaaatt aaatgttaaa gcttatgtta aaaattttat taaatttaat
     2521 ctgtaaataa aaaagttaaa agtccaatat taacatttta cttttaaacc attaaaatct
     2581 ttattaaagc taacaaagtt ataagttatg agaaatttta ttaaagttaa tacaaaaatt
     2641 aattttaaag ctaagaaatt ttttattaga ttcaataaaa ctaataaata tagtttagtc
     2701 aataatgtat taaataaaaa ctttgttaag tctataaaaa tatcttaaag gaggtgtaac
     2761 ttatgaagat aaaagtggag gatataccag ttcaatttca tgcaatggta gaaataattg
     2821 gaattgataa gtttatagag gttgccaagt tgtatggagg aacaaatact tatataccta
     2881 cgtataaggg gctttttaga tatgctagaa atagggatat agtaaaacaa tttaatggag
     2941 tcaaccacaa tgaattggct attagatata atatgtgtgt aagcaatatt aagcgaatac
     3001 tcaatgaaaa taatgtttaa atataataaa ataatgttta aacataatga aaatagcctt
     3061 gttaaacgta agagtaaaga caaagaagat gttttataaa gtttttttag acaaattaac
     3121 taaatttact acttattaat ttaaatacat tgtatattct ataaaaaaat ttgttaaata
     3181 ctggagatat attgagaata caaagaaaat ggtcgaaaat atttgttggc taaaaaatag
     3241 ataaaatgat acaattgctt gtataaaggg gaaaaataaa caaataaact atataaataa
     3301 agaaatagca attaatatga cataatatat ttataaaatt aagaatataa atagatattt
     3361 taaggtatta gttgttaaat taggaaatat taaaaaaaat atatatttat atttaaacta
     3421 ttttgttatt tatataaaaa tacttatcta gttactagca attattagta gaaatggggg
     3481 aaatagagat gaataaggga ttttacaaat taaattcagt ggtattgaac tttgatatta
     3541 agaatgatgt taacaagata agatttaatc attatataat gagaaaagaa aacatacaaa
     3601 gacttcaagg aactctgcca aacggacaat tttatatgac agtgagaaga gctgctacag
     3661 atttacaact ttctatttct actataagta ggcttgtaaa agagtttttg gatttaggga
     3721 taataagatt agtgtctaag ggtgtaaaag gtaatcgttc tgtatatagt tacgtaagta
     3781 tagagtttaa tggaagttta tttgatgata gtaaatatat ggaacttgac tgtgtatgta
     3841 atgatgaatt tattgataat agtggcatag agtttgattg tgatagcaaa gataattctt
     3901 ttaatggaga tataaatgta gaaactgtgc attgcattaa tgagtatttg tctgatgatg
     3961 atgtagagca taattataac aatttccata ataaagatac tataaaggat aaagccattt
     4021 ctaatattag cactatcaaa aaatatattg atgaatcttt tgataaaaat aaatcagaaa
     4081 attctaactt acaacaggag tcaataaatt tcaactttaa tgatacatgc aatgaaatag
     4141 ataaaagaac gaataatagt atagaaaata atcaaaataa aaggcctatg agattgagtg
     4201 acatcagtgt tttaagtgat aaaggtatga caaataaaaa gaattacttt aatcataatc
     4261 atggtataca aaaagggact aaatctgtaa caaagaaaaa agaatcctta aataaattta
     4321 ataaaaaaaa tatacagcaa agcattataa atatgctaaa taaaaaatca ggtaagaatt
     4381 ttaaaatcga ttctccaata agcataaaac ttatcaatga aaggctaaag gaaggctatg
     4441 tcttagaaga tttctacaaa gttattgagg taaaagtggc taagtggaaa aataccataa
     4501 tggagatgta tataagacca gaaaccttgt ttagctataa gtttgaatcc tatgtaaatg
     4561 aaaacatatc tatgaaaagt caaagtaatg ttcacccatg taaagaaggc aatagtaatg
     4621 atagcagtaa ttatatacat tctgattata caacatatga tggcagtgtg cgtgagagaa
     4681 aaaaatatga gaatgtaaga tactggaatc ctatatgtga gatttaatta gtttaagaat
     4741 gtatttatga taaataagat attaatagag aatagtgagc tatagcaaat gatatatcaa
     4801 tagttggtag taagttatat taag
//
LOCUS       DAMKNB010000154         4737 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.160, whole genome shotgun sequence.
ACCESSION   DAMKNB010000154 DAMKNB010000000
VERSION     DAMKNB010000154.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4737)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4737)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4737
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.160"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            complement(181..357)
                     /locus_tag="PC494_003537"
     CDS             complement(181..357)
                     /locus_tag="PC494_003537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3913989.1"
                     /translation="MFRDKMDKCTHMLTAYIGSSYDYCDFIDTHLDDFILEYGEKVVE
                     SCLHQVMVLVSKYN"
     regulatory      complement(411..500)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            complement(680..880)
                     /locus_tag="PC494_003538"
     CDS             complement(680..880)
                     /locus_tag="PC494_003538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF3913990.1"
                     /translation="MPKFTCNLKKYRQLKELTQEQLAEKVGVRRETIMRLEAGKYNPS
                     LKLAIDISKIVDTPIDELFIFD"
     gene            complement(882..1232)
                     /locus_tag="PC494_003539"
     CDS             complement(882..1232)
                     /locus_tag="PC494_003539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3796 domain-containing protein"
                     /protein_id="HDF3913991.1"
                     /translation="MIQKKFFMGFCGFLGFLSLRYFSSGNVADLTYIGFFAFFSNFII
                     AKINGDKADERYVQDEKAAMAFTGQLAIIELFILWCITIVSRNIELMCVLLSITYAIT
                     LNVYAIKLYILEEK"
     gene            1394..1582
                     /locus_tag="PC494_003540"
     CDS             1394..1582
                     /locus_tag="PC494_003540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDF3913992.1"
                     /translation="MTKYDFNFKLKVAKFYLNREGRDILIVKQYGVYDHSQVERWVNI
                     LGESELKIKKFSILYGSS"
     gene            complement(2059..2229)
                     /locus_tag="PC494_003541"
     CDS             complement(2059..2229)
                     /locus_tag="PC494_003541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3913993.1"
                     /translation="MHVYQPKTSEYLLNTSAKSYLSSIVFLFDYITKNESRYAFFIID
                     FPFLSLDIFYKF"
     gene            complement(2618..3106)
                     /locus_tag="PC494_003542"
     CDS             complement(2618..3106)
                     /locus_tag="PC494_003542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HDF3913994.1"
                     /translation="MKNKKGFTLVELLVVIAIIGILAIVALPALFKNIEKAKIAKLEA
                     DISAIKSASLSYYADESKYTEGNIIWWTKKDGKITVNSGIGDEDPLAHKIENLGMPYN
                     GSYTLVSSNGSEEYLELNIIIDGEISKSGLDKLEEDYGSSIKIPNDKNMIITFLSNKS
                     DN"
     gene            3912..4286
                     /locus_tag="PC494_003543"
     CDS             3912..4286
                     /locus_tag="PC494_003543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HDF3913995.1"
                     /translation="MKEEILIEKLLRAELIVMEYLWKKDTLMPKKEIVKEIKQIYGWH
                     KSTIKILLKRLVAKRYLARYIINSQSHYKIIDSKEYYTFKKKVLKSSKSIKIMRSLTT
                     THKNVSKEKLDLLDEYYRNLKE"
     gene            4391..4737
                     /locus_tag="PC494_003544"
                     /pseudo
     CDS             4391..4737
                     /locus_tag="PC494_003544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430377.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
BASE COUNT         1929 a          575 c          550 g         1683 t
ORIGIN      
        1 ttgtgtatta ccacaaatac tattgtatca tagattaaca taaatgtcta tttaattata
       61 atttttagtt aacattttta tttattctta atatgaaaat aaatttaaac attttatatt
      121 accaatatat taatgtaaat gtagataaaa ctaaaaaggg ttttctagaa aaaaatctgt
      181 ctaattatac ttacttacca ataccatcac ttgatgcaag caagattcca caactttttc
      241 tccgtactct aatataaaat catctaaatg tgtatctata aaatcacaat aatcatatga
      301 actaccaata taagcagtta acatatgtgt acatttatcc attttatctc taaacataat
      361 gtatttatcc ccctaaaaaa ctttcatgaa aaacaaaaag aaaatatctt tttggcaact
      421 ggctgacata acttatttta taagcgttag tccctatagc tttgcgtcac taaatttctc
      481 tagttttgcc gatttagttt tattctacag attaataata caatagaatt agttattatt
      541 caacatatct agctgaaaaa ttaataaatt tatatatgaa cgttaaatta tctgaaaaaa
      601 taaaaagccc ctctgtcagg agtgacttaa aaattgaatt taagtttgta tttaaaacac
      661 atttttaata atgcaaaaac taatcaaaaa taaacaattc atcaataggt gtatctacta
      721 tttttgatat atctattgct aatttcaaag aaggattata ctttcctgct tctaaacgca
      781 taatggtttc tcttctaact cctacttttt ctgctaattg ttcttgagtt aattctttta
      841 attgtctata tttttttagg ttacaagtga atttaggcat attatttttc ctctaaaata
      901 taaagtttta tagcataaac atttaaagtg attgcatatg taattgatag taaaacacac
      961 attaattcta tattcctaga cactatagta atacaccata aaatgaataa ttctataata
     1021 gcaagctgtc ctgtaaatgc catagctgct ttttcatctt gtacatacct ttcatctgct
     1081 ttatcaccat ttatttttgc tataataaag tttgagaaaa aagcaaaaaa tccaatatat
     1141 gtaaggtcag caacattgcc agatgaaaaa tatctaagac ttaaaaatcc aaggaaacca
     1201 caaaaaccca taaaaaattt tttctgaatc attttttatc ctccttagta attttaaaag
     1261 agatatattt atatctttat gatacaaata tatctctttt atattctttt gtcaatagaa
     1321 aatcagtatt atacaatatt tgtactgcac cataattgtt agagcaaaaa tctactgctt
     1381 gagatgttta tgtatgacta aatatgattt taatttcaaa ttaaaagtag ctaaatttta
     1441 tttgaataga gaaggaagag atattttaat agtaaaacaa tatggagttt atgaccattc
     1501 tcaagttgaa agatgggtta atatattagg agagagtgaa ctaaaaataa aaaaattttc
     1561 tatactatat ggttcaagtt agatgttata aactatatga tgataactaa atatagtgta
     1621 caataaatcg ctaagtattt tggaataaac aatagcacag ttatagcaac atgaaaataa
     1681 aaatttttac atagtggtgt tgatgccttt tccaaaatga aaggaagacc ataatgaata
     1741 aaaacaaaaa cactaaagaa aaaataaatt aacaagagaa caagaattag aatatgaaaa
     1801 taaattttta aaagatgagc ttgagttttt aaaaaagatg tgtgcctcag ggaagccaca
     1861 ttaaaaaaca gtggtatcat tattaatcaa aagaaagtta gatgtattat caaaaaatta
     1921 gaacttaaat gcatagcatt ttttcataaa tcacataaat ataactccta taaatgtata
     1981 attggaaaag taaaaaataa taaaacaaat agaagattta aaacatcaat agcatatcag
     2041 aaaataacaa atgatatgct aaaatttata aaatatatct aatgataaaa atggaaaatc
     2101 aattataaaa aaggcatatc tcgattcatt ttttgttata tagtcaaata agaatactat
     2161 agatgaaaga tacgattttg cagatgtatt aagtaagtat tctgatgttt ttggttgata
     2221 cacatgcaat aaagaagttg tgtttgcaga taaattagca aaactatagt ataagttgca
     2281 acaataaaga aaatgaaaat tatcatacta aagcataagg catgttacaa ttttattaga
     2341 taggacatta acatacacta aagtactttt tactataaag agtacttatt tttttgaaat
     2401 tcattaatgt ataaactatc aagaatatta ctcaacataa tttaaaaaca acttgaatag
     2461 gtatttttaa attatgtgat ataataaaaa atagaagtgt atgccaatac acttctgtag
     2521 ttataactaa gcattctatt cttgaggagt gcttttttca tttttataac caactctttt
     2581 tactttaaca ataattatca gacctatata tttattttta attgtctgat ttattagata
     2641 aaaaagttat tatcatattt ttatcatttg gtatttttat tgaactacca taatcttctt
     2701 ctaatttatc tagaccactt ttacttattt ctccatctat aattatgttt aattctaagt
     2761 attcttcact accattagat gacactaaag tgtacgaacc attataaggc atgcctaaat
     2821 tttctatttt atgtgccaaa gggtcttcat caccaatacc agagtttact gttatttttc
     2881 catctttttt agtccaccat attatgtttc cttcagtata ttttgattca tctgcatagt
     2941 agctaagaga cgcacttttt attgcactta tatcagcttc aagtttagct atctttgctt
     3001 tttctatatt tttaaataat gctggaagtg ctactattgc caatattcct attatagcaa
     3061 ttactactaa taattccact agagtaaatc cttttttgtt tttcatttat ttcccctcca
     3121 tataaaatta ataatatata aatttttatt ttgttgattt ctactttcta tattttacca
     3181 tatatagaca aaaaaatcac tttctatgac aaatatacta ttattttaca atttatggaa
     3241 atgatttaaa atgacatttc ttgttagaaa agatataagc aatggattaa aataaagaaa
     3301 actacagtca tatcaacgcc aataatatta tttaaaagca gatgaaaata aaaagagggc
     3361 ccagaaaata atgtctattt aattatactt acttaccaat accataactt gatataaaca
     3421 agattatact acattttttt atgttctagt ataaaatcat ctaaccgtgt atctataaaa
     3481 tcaaaataat tatatgaact atcagtataa taagtcaaaa tatgtataca tgaatacata
     3541 ttttttaaaa gatatatatt attacatacc taaaaaactt tcataaaaat aaaaataaaa
     3601 tatgatttta gtaacttgtt aacataactt ataatttatt ttataagcat tagcctatat
     3661 agctttgtgc tactaaattt ctttgattct aacgatttag tgctattcta caactaaaat
     3721 aatacaatag agctatttat tgtttggtag cattgtttgc aaattaaaca aatttatata
     3781 tatgaatatt attttacgtt caaaaaaaca gactaaatat gtagaatatt cggtaaaact
     3841 tacctctagt ttttgtctta aaaagctcct attattaact taagttagaa gaattaagga
     3901 agtgacataa attgaaagaa gaaatattaa tagaaaaatt attaagagca gaattaatag
     3961 taatggagta tttatggaaa aaagacactc taatgcctaa aaaagaaatt gtaaaagaaa
     4021 taaaacagat ttatggatgg cataaaagta caataaaaat actactaaaa aggctagttg
     4081 ctaaaaggta tttggctaga tatattataa attctcaatc tcattataaa ataatagata
     4141 gtaaagaata ttatactttt aagaaaaagg tactaaaatc tagtaaaagc ataaaaataa
     4201 tgcgttcact taccactaca cataaaaatg taagtaaaga gaagttagac ctattagatg
     4261 agtattatag aaacttaaaa gaatgatata gtaaaaatcg aatgtaatta tttaccttaa
     4321 ttcttttgtt tgtaaaactt tattgataca taatttaaca tatacataaa ttggtaaagg
     4381 aatgtatact atgaaaatta gtaaattacc agaagcggaa ttaaaagtta tgagatatat
     4441 ttgggaatca gaaaaggtat taatatcaag agaaatcacc aagtctatgg aacaaaaata
     4501 tgaatggaaa gatacaacta tatttacagt attaaaaaga ttactaaaga agagagtttt
     4561 tagaaacgga gaaaatagat aagtgtacac actataatgt attagtaaaa aaaaataata
     4621 tcagagattt taaacaaaag aatttttaaa gaatacacat aaaaattcaa tattaagttt
     4681 aatgtcagca ctatgtagta aggatgatga agtagatggt gatattttaa atttatt
//
LOCUS       DAMKNB010000155         4675 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.161, whole genome shotgun sequence.
ACCESSION   DAMKNB010000155 DAMKNB010000000
VERSION     DAMKNB010000155.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4675)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4675)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4675
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.161"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            complement(1012..1209)
                     /locus_tag="PC494_003545"
     CDS             complement(1012..1209)
                     /locus_tag="PC494_003545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003366523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF3913996.1"
                     /translation="MQIKIMELLDKKGKTRYWLAKEIGIKQQSLNKIASNETVSIRFD
                     ILEKICTTLECTPNDVLGWDK"
     gene            1342..1650
                     /locus_tag="PC494_003546"
     CDS             1342..1650
                     /locus_tag="PC494_003546"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3913997.1"
                     /translation="MINKNILKEQQLNKIKVLKNKNDKNIKNNIFKMFNSDMEEMKSI
                     IKNELFFENIYQDELEFHMNKIKNIENIADKFYVQFMISGEEGFEITCLRTALANRSI
                     "
     gene            2323..2943
                     /locus_tag="PC494_003547"
     CDS             2323..2943
                     /locus_tag="PC494_003547"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3913998.1"
                     /translation="MNKKVEKPFVYKREYDLTKYDTKVLQKYNLEQAIYIYVGSSCAY
                     NMRARSSKWRYHIRKNNGSICYTIRNFIHNLELFYKRELELPDNIIDDKLYYSNVVEF
                     EEFETLEKAREIESTIISQYQFLDSVNYMLKQKIILLSNNDSALCMVKNGNQVSLKIK
                     NKYIEKYKNKPIMRYHIDCQFNTDGSVKSITQEFEPILELSNKKIL"
     gene            3162..>4675
                     /locus_tag="PC494_003548"
     CDS             3162..>4675
                     /locus_tag="PC494_003548"
                     /inference="COORDINATES: protein motif:HMM:NF020291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primase C-terminal domain-containing protein"
                     /protein_id="HDF3913999.1"
                     /translation="MKGKDIQEKLITYFKFIFPKLETDEKYRAYMLVENSKTNFTRTF
                     KLNTYHELVEVVNKYNSKANIYISTCLYDNTKDKTKENILSKSVIVVDVDNADFDISE
                     IYKLAKINQVFIHLVVRSGRGWHLYFKLDKEYSNVKQLEKASKHLCELFGGDKNSLDV
                     GHVYRVPFTKNLKYDNTWSSIVNTINKTFPHTLDKLINHVPIKSSLSGNTELQVDNVE
                     QLSCFKNLVKYGISKGFRNKAMIAISNTCKYIGLSEVEALQYAYEFNSNCEVPQRKTE
                     VVKVVKSIYNNSSLIKPCKDNLNKKLCNSHCMGRLITVDDVLNKIDENIDNDIQVAFS
                     NKLIGNIKTYINKDGKKEKGTMLSVLSGAEILIISELKTFRNEIYSVDDLIDTTNLSK
                     PTIIKSLKRLEEFNIINSTKQHFNRSSKPTTIYFYNDECEQKYKEIHSIGRGLFIIRR
                     NKLITDNDMKVYIALKYLINKRMSTTQNDIELISGVTRNNINRSIKNLIEQDLL"
BASE COUNT         1914 a          468 c          709 g         1584 t
ORIGIN      
        1 aaaaaaacaa gttcaaagta caaatggaac atttaatatt tatacattaa aattatagaa
       61 aataaaaagc acttacaatt aatttgtagg tgctttttta aaacaagtta aaaatcaaaa
      121 atagtattag gaggcattgg aaatgctaga ttctaaaata gaaaagtaaa aaattgatgc
      181 atagtccaaa atacttcaaa ctattgaaat atacatattt tttgatgaga aaagtaaaaa
      241 attgatgcac tatctaaact tatctatatc tcttcttcct ttgttaggga ttaccttagt
      301 tacaatacag aggatatgct tatattaagt gagagtaata acccgtgttt aatatagtta
      361 ctagaattat agttactata gtttcgtatc tgtggcacaa taatagaata actaaaataa
      421 tgttagatgt ttacatgtac tttagttagg aactcgaatt ttacgagttg taatatctaa
      481 cactctaaat aatagctata gatattaaac gtgtacttga aacggacact tgaatatgtt
      541 tagaccactt gtgggagaaa gtataattgc cacgtgtggc taacacgcac gcgttagata
      601 taaattagtt aaatcctaat atgtggtata ccacttgaat atacattgtt gtgcaatatt
      661 gcaaatagta atagtcccaa caagttgggg aagtaacaaa tgaattttta cgttggttaa
      721 ggtgtaccca ttttggatac accctctata atttagttat gcaatatatg tttatcccaa
      781 atagtgatat taaaatactt gttttattct aatttaacaa caaaaccctt gtatgctagt
      841 tattgcaatg tttacattag ttttttatat gtcagtaagt taagacataa aactaagtat
      901 tttatgccat atttatatat atattagtag ttgcaatgtt tttataccta tcataggtat
      961 tgatttaaag ttaatttgtc agttacatgt cagtatattt gccataatag attatttatc
     1021 ccaacccaat acgtcatttg gagtacattc taaagttgta caaatttttt ctaatatatc
     1081 aaatcttatg gatacagttt catttgatgc tatcttattt aaactttgtt gtttaatacc
     1141 tatttcttta gccaaccaat atctcgtttt acctttttta tctaaaagct ccattatctt
     1201 aatttgcata aaatcctcct ccttaaatta ttgttaagag taagtatagt ttagaaggtt
     1261 ctgtttaaca ataatgtcta ttgacggtac ttacgctaca atggtattat gtttatatat
     1321 ttttgaagaa gggataaaaa gatgattaat aaaaacattt tgaaagaaca gcaactaaac
     1381 aaaattaaag tattaaaaaa taagaatgat aaaaatataa aaaacaatat atttaaaatg
     1441 tttaatagtg atatggagga aatgaaaagc attattaaaa atgagttgtt ttttgaaaat
     1501 atctatcaag atgaattgga atttcatatg aataaaatta agaacataga aaatatagca
     1561 gataagtttt atgtgcaatt tatgataagt ggagaagaag gttttgaaat aacatgtctg
     1621 agaacagcac tagcaaatag gagtatatag taaaggttta tataatatga tgacctcata
     1681 caagcctgta agagccgttt aaaagctgtc ttagtgtaat taatccttga aaatttaaaa
     1741 tacgtttaaa tggcttgtta aatatggtgg tattactatt aaatataggg ggtagttaca
     1801 tagttacatg ttgttttaaa aaataaattt aactatagtt ctttcacttc tacattacaa
     1861 aaaaataaat tgagtgtgta tgtttttagg tcaaaatgat gtttaaatat tgaaaaatag
     1921 ggatatggtg tatgtaaaat ttagaatagt gtatgtaatt ttaggcataa aaatatgtga
     1981 ttaaacctta aaaatcagga atatagtgta tgttaaaaaa gattgacata cgtgttaaaa
     2041 aaagttataa ttaaggatta gatatatatt gacatgattt attttctatg ttattatatg
     2101 tttagattaa aacatatcaa attaccatat ctatttatat attgactatt tgttaatatg
     2161 taacatgttt gtatttcaat gtaaatacaa tcttttatat cctgtgtgag ggtataccat
     2221 taaaagtatc ttatattcaa caaattaaaa aaatttaata ggaggtgtag tgtaaaagga
     2281 tttttagtta ctaagtttaa ataaaaaata ggaggacact tattgaataa aaaagtagaa
     2341 aaaccattcg tgtacaagag ggaatatgac ttaacaaaat atgatactaa agttctacaa
     2401 aagtataatt tagaacaagc tatatatatt tatgttggca gtagctgtgc atataacatg
     2461 agagctagaa gtagtaaatg gaggtatcat ataagaaaaa ataatggttc tatatgctat
     2521 accattagaa acttcataca taacttagaa ttgttttata aaagggaatt agagttgcca
     2581 gataacatta ttgatgataa gttatattat agtaatgtag ttgagtttga agaatttgaa
     2641 acattggaaa aagctaggga gatagaaagt actattataa gtcaatatca atttttagat
     2701 tctgtaaatt atatgttaaa acaaaaaata atcttgttaa gtaataatga tagtgcatta
     2761 tgtatggtta aaaatggaaa tcaagtatct ttaaaaataa aaaataaata catagaaaaa
     2821 tataagaaca agccaataat gagataccat atcgattgtc aatttaatac agatggaagt
     2881 gtcaaaagta ttacacagga atttgaaccc atattagaat taagcaataa aaaaatactc
     2941 taagccgaca agcagagtat ttagtataaa aaagatttat ttcaacaaca acactattga
     3001 tatagtgtga atgagttagc gttcattcaa gttgtttatt gactatattt aaaattacat
     3061 atattaataa gattttaaac ttatgataat ttaatgtaat ttaatgatat tattaattag
     3121 acattatgtc aagagtgttg ttctgaagaa aggagcaaca ggtgaaagga aaagatatac
     3181 aagaaaaatt gataacgtac tttaaattta tatttccaaa acttgaaact gatgaaaagt
     3241 atagagcata tatgcttgta gaaaattcaa agactaactt tacaagaaca tttaaactta
     3301 acacttatca tgagttagta gaagttgtca ataaatataa ctcaaaggca aatatataca
     3361 tatcaacttg tttatatgat aatacaaaag acaaaacaaa agagaatata ctatcaaaat
     3421 cagtaattgt agtagatgta gacaatgctg attttgacat atcagaaata tataaattgg
     3481 ctaaaataaa tcaagtattt atacatttag tagtaagaag tggacgaggt tggcacttat
     3541 actttaagtt agataaggaa tattcaaatg taaaacaatt agagaaggct tctaaacact
     3601 tatgcgaatt atttggtggt gacaaaaatt cattagatgt tggacatgta tatagagtcc
     3661 catttactaa aaatttaaag tatgataata cttggtcaag tattgtaaat actattaata
     3721 aaacatttcc acatacactt gataaattaa taaatcatgt accaattaaa tcatcactta
     3781 gtggaaacac agaattacaa gtggacaatg tagaacaatt aagttgtttt aaaaatcttg
     3841 taaaatatgg gataagtaaa gggtttagga ataaagctat gattgctata tcaaacacat
     3901 gtaaatatat tggtttaagt gaagttgaag cattgcaata tgcttatgaa tttaattcaa
     3961 attgtgaagt tccacaacgt aagactgaag tagttaaggt tgtaaaaagt atatataata
     4021 attctagttt aattaaacca tgtaaagata atttgaataa aaaattatgt aatagtcatt
     4081 gtatgggaag gttgattact gttgatgatg tacttaataa gattgatgaa aatatagata
     4141 atgatataca agttgcattt agtaataagt taattggtaa cattaaaact tatattaata
     4201 aagacggaaa aaaggagaag ggaactatgt taagtgtttt gagtggtgct gaaatattaa
     4261 taatatcgga gctaaaaaca tttagaaatg aaatttattc agttgatgac ttgatagata
     4321 caactaattt aagtaaacca acaataatta aatcattaaa aagacttgaa gaatttaata
     4381 taatcaacag tactaaacaa cattttaata gaagttcaaa acctacaact atatattttt
     4441 ataatgatga atgtgaacaa aagtataaag aaatacattc aatcggtaga ggtttattta
     4501 taattagacg caataaatta ataactgata atgatatgaa ggtttatata gcactaaaat
     4561 atcttatcaa taaaagaatg agtacaacac aaaatgatat tgaacttatt agtggggtaa
     4621 ctagaaataa tatcaatagg tctattaaaa acttgataga acaagattta ttaag
//
LOCUS       DAMKNB010000156         4627 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.162, whole genome shotgun sequence.
ACCESSION   DAMKNB010000156 DAMKNB010000000
VERSION     DAMKNB010000156.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4627)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4627)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4627
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.162"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            complement(1034..1444)
                     /locus_tag="PC494_003549"
     CDS             complement(1034..1444)
                     /locus_tag="PC494_003549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3914000.1"
                     /translation="MKIKKSLISAMMVSAMVLGGTGAVFANGNDSSNIALPKFESLIK
                     SGITDPTELEKYGVEHYTYEEYAKHIQELKDYAKDPNAVKDVSQKDLEETIKKMEQEL
                     EKIKTEGLKIMKPITIENEDGSQISIAYNYAAID"
     gene            complement(1660..3042)
                     /locus_tag="PC494_003550"
     CDS             complement(1660..3042)
                     /locus_tag="PC494_003550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M56 family metallopeptidase"
                     /protein_id="HDF3914001.1"
                     /translation="MFIKLLEMSFTSGVLLLIVIFIRACLFKKLPKKVFVLLWLIVLF
                     KLLIPVSLNSGFSIYSIIESTFDVELGNTSTENYTLKKASDSTGKNNSDEFEIMSNIE
                     NIMMLEMLGILSFIVTIMFSILLCFRYFKIINLFKTSIHIKNHEFIKKWMCKNSRFRR
                     FIVCISEFTRTPLTSGILKPRIILPKQMNYANNQTLDFVLTHEMVHINSFDNLLKLFM
                     LVALVVHWFNPLVWVMFFLLNKDIEFSCDEKVMSILGEEYRADYATTLISLAEENNPF
                     SMTICSGFGKTKIEKRIVNIMKFKKSTYVTFLVSTVLVCGTGLVFATENKEINEVESF
                     GLTKNEQSDKIGFSISSKSTDLYSPKVESDILVSKAKSDGETHFSTAKVSVIEFREHE
                     ESSMSKVTNSENSEETYVNKSSNSKDVLYTDSGEVSIERSGYNDNRFVISRKGNLLAV
                     NKEQYRTWIE"
     gene            complement(3053..3412)
                     /locus_tag="PC494_003551"
     CDS             complement(3053..3412)
                     /locus_tag="PC494_003551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HDF3914002.1"
                     /translation="MEIKLFDSELKVMEVLWERGESKAGELVKILKEETGWNRNTTYT
                     VIKKLVSKGAIERIEPNFVCKALISKEEVQKQETETLINKMFGGSSEKFLSAFINKEN
                     LSSDEITKLKQIVEKLK"
     gene            complement(3617..4396)
                     /locus_tag="PC494_003552"
     CDS             complement(3617..4396)
                     /locus_tag="PC494_003552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HDF3914003.1"
                     /translation="MVSRQELKRVSKAQLSGNWGICAISMAVYIALIVLISIVGLPFE
                     PLTTIVVAVIAFCVSAGFTCMFLKITKDEKVKIGDIFVSGRIYLRSFGFYLFESIIVY
                     IYSFIITIIGAFLSFGVLLTSGAIEYLSSDNVGIGTIISTGITLVLIILVLMLPVYIL
                     LLYVSQATFLICEDKDNMGVFKSMGASLDMMKGNVLKLFVLNFSFIGWYILSIATLGI
                     GLLWLIPYVGVTNCNFYRQLVKENPDVEDILLDKEKSYTMY"
BASE COUNT         1604 a          785 c          402 g         1836 t
ORIGIN      
        1 ttcttatcta ccatcatcca tatatttatt ttacgattac tctttcaccc taacccttta
       61 attatctatt ttttctgata ttcttatcta ccattatcta tatatttatt ttacgattac
      121 tctttcaccc taacccttta actatctatt ttttcttact attcttatcc acatcatcca
      181 tatatttatt ttacaattac tctttcactc taacccttta actatatatt ttttctgata
      241 ttcttatcta ccattatcta tatatttatt ttacgattac tctttcaccc taacccttta
      301 actatatatt tttttctggt attcttatct actattatcc gtatatttat tttatgatta
      361 ctcttttaac ctacccccta tactttatag taatatgttt ttaacctttt tcattattcc
      421 caatatgctt tataactaca aatactctcc ccccttaaaa ataataataa aattaatcaa
      481 taaatttata atcatattat tactctatgt attaagcaat tactatgcca ataaactttg
      541 atttttttaa acaaatctta aaaatcctaa aatgctaatt ttctttaact tttaatgaat
      601 ctaatagata acatttaatt ttcgttatac ttttcagaat atttctatta ttatttttaa
      661 gaaaaaaaaa taatgttaac atttcttaac atacattaaa aaatgttaac attataaatt
      721 gggtttaata cttttacttt gactcgattt acttttattc tacttcttac tttattttta
      781 acttagactt tattttttta ttacttattt gagtcttatt tattttattc tcactccata
      841 tgttcaatta catttgtcta aattctttga tacttttatt acataatttt aacaagctta
      901 agtgttattt gggtagtgca gttgataatt atttaaataa tcatcaactg catgtttata
      961 tcattacagt agcttaatgt atttaatcat acttacttag gattttgaaa tatcttagag
     1021 attatattta acattagtca attgctgcat aattgtaagc aattgaaatt tgagacccat
     1081 cttcattttc tatagtgata ggcttcataa tttttaatcc ttcagttttt atcttttcta
     1141 attcttgttc cattttctta attgtttcct caaggtcttt ttgacttaca tctttgactg
     1201 cattagggtc tttagcatag tcttttaatt cttgaatatg tttagcatac tcttcataag
     1261 tataatgctc aacaccatac ttttccaatt cagtagggtc agttattcct gattttatta
     1321 gagattcaaa tttaggtaaa gcaatattag atgaatcatt tccatttgca aatactgctc
     1381 cagttcctcc tagtaccatt gcagatacca tcattgcact tataagggat ttttttattt
     1441 tcataaccaa tcttcctttc ttagagattt atttgggtag tgtagtttaa aatgactatt
     1501 gcaatagtta tcaaccacat tcttagacta tcacagtagt catgtttatg tcaagccttt
     1561 ttaaaaaact tttcaataaa aaatactatc tcaaaacaaa attaattatt ttgagatagt
     1621 attttaattc taaatctttt atattactaa gatttatggt tactctatcc atgttctata
     1681 ttgttcttta ttaactgcta acaaattccc ttttcttgat atgacaaagc gattatcatt
     1741 atagccactt cgctcaattg aaacttctcc tgaatcagta taaagtacat ccttactatt
     1801 actagattta tttacatacg tttcttcact attctcagaa ttagttactt tgctcataga
     1861 tgattcttca tgctctctaa attcaattac agatactttt gccgtactaa aatgagtctc
     1921 tccatcactt ttagctttac taacaagaat atcagattct actttgggag aatataaatc
     1981 agttgattta ctacttattg aaaatccaat tttatcactt tgttcatttt ttgttaaacc
     2041 aaaagattca acctcattaa tctctttatt ttctgttgca aaaacaagac ctgtcccaca
     2101 aactaataca gttgaaacta aaaaagtaac ataagttgat tttttaaatt tcataatatt
     2161 aactattctc ttttctattt ttgtctttcc aaatccacta catattgtca ttgaaaatgg
     2221 attattctcc tctgctagac ttattagtgt ggttgcataa tcagccctat attcttcacc
     2281 aagtatactc ataacctttt catcacaact aaattctatg tctttattta gtaaaaaaaa
     2341 catcacccag actaagggat taaaccaatg gacaacaaga gctacaagca taaataactt
     2401 taacagatta tcaaagctat taatatgaac catttcatga gttaaaacaa agtctaaagt
     2461 ttgattatta gcataattca tttgctttgg caaaataatt cgtggtttta aaataccaga
     2521 tgtaagtggt gtcctagtaa attcagatat gcaaacaata aatcttctaa aacggctatt
     2581 cttacacatc cattttttaa tgaactcatg attttttata tgaattgaag ttttaaaaag
     2641 attaattatt ttaaaatatc taaagcataa aagtatgcta aacataatag taactataaa
     2701 agacaaaatg cccaacattt ccaacatcat aatattttca atattagaca ttatttcaaa
     2761 ttcgtcagaa ttgtttttac ctgtagagtc actagctttc ttaagagtat aattttctgt
     2821 tgatgtatta cccaattcca catcaaaagt cgattcaatt atactataaa tactaaaacc
     2881 agaatttaaa cttactggta ttagaagttt aaataaaaca atcaaccaca ataatacaaa
     2941 taccttttta ggtaattttt taaataaaca tgctcttata aaaataacta ttaaaagtaa
     3001 tactccagaa gtaaaactca tttctaacaa tttaatgaac ataaatctta cctcacttta
     3061 atttttcaac aatttgttta agttttgtaa tctcatcact tgaaagattt tctttattaa
     3121 taaaagctga aagaaatttt tctgaagacc ctccaaacat tttattaatt aaagtttctg
     3181 tttcctgttt ttgtacttcc tctttgctta ttaaagcttt acaaacaaaa ttcggctcaa
     3241 ttctctctat tgcacctttt gacactaatt tttttataac ggtatacgta gtgtttctat
     3301 tccatcctgt ttcttctttt aaaattttta ctaactctcc agccttgctt tctcctctct
     3361 cccatagaac ttccattact ttaagttctg aatcaaataa ttttatctcc atataaaatc
     3421 gctcctcaaa tatagttatc acaatagtca ttactataat aaaaaactat catagtagtc
     3481 tatactatgt caatcattta ttttttaata ataaaaactg tctttttaaa aaattcttat
     3541 aaaagacagt tttatcaatg ttatacttta atgtttaatt aaagccatat tttatttaaa
     3601 tatacaacta tctatcttag tacatagtat aagatttttc tttatctaat agtatatcct
     3661 ctacatctgg gttttctttt actaattgtc tataaaaatt acaattagta acacccacat
     3721 atggaattaa ccatagtaga cctattccaa gagtagctat tgaaagtata taccatccta
     3781 taaaactaaa gtttagtaca aataatttaa gtacatttcc tttcatcata tctaaactag
     3841 cacccattga tttaaataca cccatattat ccttgtcttc acaaattaag aaagtagctt
     3901 gagaaacata taatagcaat atataaactg gtaacataag aacaagtatt ataagaacta
     3961 gagttattcc agtagaaata atagtcccta ttccaacatt atcacttgat aaatattcaa
     4021 ttgctccact agtaagtaaa actccaaatg ataaaaacgc tcctataatt gtgattataa
     4081 aagaataaat ataaacaata attgattcaa ataaataaaa accaaaactt cttaaataaa
     4141 ttctcccact tacaaagata tctcctatct tgactttttc atctttagta attttcaaga
     4201 acatacatgt aaatcctgct gaaacgcaaa aagctattac agccactaca atagtagtca
     4261 atggttcaaa aggtaatcct acaattgata ttaatactat caatgcaata tatactgcca
     4321 tagaaattgc acatatcccc cagtttccag ataactgagc tttagatact cgttttaatt
     4381 cttgccttga taccataaaa aacacccctt tcattttata aaaaaacttt taaaaatata
     4441 aataatcttt taacgtataa tattaatata tcatattttc gactatataa gatacaatta
     4501 ttcaccatgt tttatcaaga tatgccataa ttgtattact agttttatat agtcaacatt
     4561 accaaataca tcaaataaat ttgattaatt attcaacaag taataaaata atttctatta
     4621 attatac
//
LOCUS       DAMKNB010000157         4553 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.163, whole genome shotgun sequence.
ACCESSION   DAMKNB010000157 DAMKNB010000000
VERSION     DAMKNB010000157.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4553)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4553)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4553
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.163"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            complement(237..1280)
                     /locus_tag="PC494_003553"
     CDS             complement(237..1280)
                     /locus_tag="PC494_003553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH/Band 7/PHB domain protein"
                     /protein_id="HDF3914004.1"
                     /translation="MGTKIVLSIVLIVVVVAISLTCIRVIKQSKVGIIMRLGKFQKVA
                     ETGVHFLIPFLDKMAYVIDLREIVIDFPPQPVITKDNVTMQIDTVVYYKVTDPVRYVF
                     EIANPIAAIENLTATTLRNIIGELDLDETLTSRDIINVKMRTILDEATDKWGIKVNRV
                     ELKNIMPPQDIQVAMEKQMRAERERREAILQAEGNKSAAILQAEGEKQSAILTAEAKK
                     EAMVRVAEGEKESAILVAEGEAEAIRQTAIAKAQGEAEMIKRTQMATAEGLKLVFSAM
                     KEADIDNNILALKSMEALEKMAEGKSTKLVLPSEAVNFLGTFKGIKEVMSDDNKEVLD
                     IKEVLNDNESLKK"
     gene            complement(1301..1747)
                     /locus_tag="PC494_003554"
     CDS             complement(1301..1747)
                     /locus_tag="PC494_003554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NfeD family protein"
                     /protein_id="HDF3914005.1"
                     /translation="MKLIWLIVAVLFGIAEMLTPSLTLIWFSVGAVILIFLSSFIESI
                     FLQILIFAVISIAMLVVATKKIVKKDKGYKSNTNLQAMMSKKGIVTEEISPNNTGLVV
                     VEHETWTAISIDGEKIEKGSTVEVLKIEGVKLVVKKVDATVNVTNQ"
     gene            complement(1921..3501)
                     /locus_tag="PC494_003555"
     CDS             complement(1921..3501)
                     /locus_tag="PC494_003555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional ADP-dependent NAD(P)H-hydrate
                     dehydratase/NAD(P)H-hydrate epimerase"
                     /protein_id="HDF3914006.1"
                     /translation="MLIGTSKLSRNVDTACVEEVGIPMIVLMENAVISAMKNMDIDMY
                     NSYTVVCGVGNNGGDGLGIARHLNTYGKEVNVFLVGNLEKLSECSKINYNVLLNMGIN
                     IININKNDLSEKNYGDENEVDKIIKVEKQNIIKNKNLTIFKDRVSKSDVVVDAIFGTG
                     LKRDITGIFKEVIDIVNDNSKNTYSIDIPSGIDSDNGNVLGTCIRANKTISFEFYKRG
                     FLNYDTSALIGDVVVEKIGVPDFITRKYHDEEFITDKTFVKNNIRRRDKHGFKSDFGK
                     VSIVAGSKGFYGASFIATESAVKSGSGLVTLISSEDVQEKVSIRLTEAMTLNFEEERL
                     NKLLNSSDAIGFGPGMGDNSQTFDKLLKIVENSNCPIVLDADGLNVMKDRCYKFLEWK
                     NRFVITPHLGEMARLTGDSIGYIREHRVDVAKEFAQKYNLVVLLKGYQTVITDGKKTY
                     INPTGNSCMATGGMGDCLLGMITSFIGQGMDILEATVSGAYIHGYIGDKLSKAMYTIN
                     ATDLISNISLTMKELLDI"
     gene            4300..>4553
                     /locus_tag="PC494_003556"
     CDS             4300..>4553
                     /locus_tag="PC494_003556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF3914007.1"
                     /translation="MSGIISVMTQSLILSIMALGVYITYKILDFPDMSADGSYTMGAS
                     IVAFSLTNGISPVVATLMAILCGCTAGLVTGILHIKFKIS"
BASE COUNT         1457 a          793 c          453 g         1850 t
ORIGIN      
        1 accatgctta tttgctatat gttttatata atattatata acacttttta cattagtaaa
       61 ggataaattg tataaagatt ctgttaattt atttttataa tttcatcttt ctaataaaaa
      121 caaagaagaa gacttaaaaa tttataagtc ctcttctttt caacgtgcat ttttgtgcta
      181 tatttaatta attcgacctt taatttccat atccttccta tgataacaaa actcttttat
      241 ttttttaatg attcattatc atttaaaact tcttttatat caagtacttc tttgttatca
      301 tcactcataa cttcctttat tcctttgaat gttcctagga aattaactgc ttctgaaggt
      361 aaaaccagtt ttgttgactt accttcagcc attttttcaa gagcttccat agattttaat
      421 gctagaatat tattgtctat atcagcctct ttcattgctg aaaaaactaa ttttaaacct
      481 tctgctgttg ccatttgagt tctttttatc atttcagctt caccttgtgc cttagcaata
      541 gctgtctgtc ttatagcttc agcttcacct tctgccacta atatagcaga ttctttttca
      601 ccttctgcta cacgtaccat agcttctttt ttggcttctg ctgttaatat agcagattgt
      661 ttttcacctt cagcttgaag tattgcagct gacttattac cttctgcttg aagtattgcc
      721 tctcttcttt ctctttctgc tctcatttgt ttttccattg caacttgaat atcctgagga
      781 ggcattatat tttttaactc tactctattt acttttatac cccatttatc tgttgcttca
      841 tcaagaatag ttctcatttt tacatttatt atatctcttg atgttaatgt ttcatctaaa
      901 tcaagttcac caattatatt tcttagtgtt gtagctgtta aattttcaat agcagctatt
      961 ggattagcta tctcaaacac atatctaact gggtctgtaa ctttataata tacaactgta
     1021 tcaatctgca tagttacatt atctttagtt ataactggtt gaggtggaaa atctattaca
     1081 atttctctaa ggtcaattac atatgccatt ttatctaaaa atggtattaa gaaatgtaca
     1141 cctgtttcag ctactttttg aaacttacca agtctcatta ttatacctac tttagattgt
     1201 tttataactc ttatacaagt taaacttatt gctacgacta ctactattaa tacaatactt
     1261 aaaacaattt tagtacccat actataaatc ctcctttatt ctattggttt gtcacattaa
     1321 ctgtggcgtc tactttttta acaactaatt ttaccccttc aatttttaat acttctactg
     1381 tagaaccttt ttctatcttt tcaccatcta tagaaatagc cgtccatgtt tcatgttcaa
     1441 ctacaactag acctgtgtta tttggagaaa tctcttctgt aacaatacct tttttagaca
     1501 tcattgcttg taaattagtg ttagatttat agcctttatc tttttttact atttttttag
     1561 tagctacgac taacattgct atagaaatta ctgcaaatat taaaatttgt aagaaaatac
     1621 tctctataaa gctacttaaa aatataagta ttacagctcc tacactaaac catatcaatg
     1681 ttaagcttgg tgttaacatt tctgctattc caaataagac tgctactatc aaccatatta
     1741 acttcatact atctaccctc ttttcatatg aattataaaa ccctatataa attatatgtt
     1801 tatacaatgt ttttgaatat aaatttaaat tacaaaacaa taaaataaat taattaatta
     1861 atagtattat atcaacatac tttgttaaaa ttgttacaaa gtagtatcaa atatcaccaa
     1921 ttatatatcc aacaactctt tcattgttaa tgaaatgtta cttattaaat ccgtagcatt
     1981 tatcgtatac attgctttgc tcaatttatc tcctatatag ccatgtatat atgctccact
     2041 aactgtagct tccaatatat ccataccttg acctataaat gaagtaatca ttccaagcaa
     2101 acaatcaccc attccaccag ttgccataca gctatttcct gtaggattta tatatgtttt
     2161 tttaccatct gttatgacag tttgataacc ttttaaaagc accaccagat tatatttttg
     2221 agcaaattct tttgcaacat ctactctatg ttctcttata tacccaattg aatctcctgt
     2281 caacctggcc atttctccca aatgaggtgt aattacaaat ctatttttcc attctaaaaa
     2341 cttataacat ctgtccttca taacgttcaa tccatctgca tctaatacta ttgggcaatt
     2401 agaattttct actatcttaa gtaatttatc aaatgtttga ctattatctc ccatacctgg
     2461 accaaaacca attgcatcac tagaattaag taatttattt aatctttctt cttcaaaatt
     2521 taaagtcatt gcttctgtaa gtctaataga taccttttct tgcacatctt cactactaat
     2581 taatgttaca agtccactcc cactcttaac agcagattca gttgctatga aacttgcacc
     2641 ataaaatcct tttgaacctg caactataga tacttttcca aaatcacttt taaaaccatg
     2701 cttatctctt cttctaatat tattttttac aaaagtctta tcagttatga actcttcatc
     2761 atggtatttt cttgtaataa aatctggaac acctatcttt tctacaacta catcacctat
     2821 aagtgcgcta gtgtcatagt ttagaaaacc tcttttataa aactcaaagc taatcgtttt
     2881 gtttgctcta atacaagttc ctaatacatt tccattatcg ctatctatac ctgaaggaat
     2941 atctatagaa tacgtatttt tgctattatc gtttactatg tcaataactt ctttaaaaat
     3001 accagttata tcacgtttta atccagtccc aaatatagca tctactacaa catcactttt
     3061 agatactcta tctttaaaaa ttgttaaatt tttatttttt ataatatttt gtttctcaac
     3121 tttaataatt ttatctactt cattttcatc tccataattt ttttcactta aatcattttt
     3181 attaatattt ataatattaa ttcccatatt taaaagtaca ttgtaattta ttttagagca
     3241 ttcacttagt ttttcaagat tacctactaa aaatacgttt acttcttttc catatgtatt
     3301 tagatgtctt gctattccaa gaccatctcc tccattattt ccaacaccac atacaactgt
     3361 ataactatta tacatgtcta tatccatatt tttcattgca gatataaccg cattttccat
     3421 caatacaatc attggaatcc ctacttcttc tacacatgca gtatcaacat ttctgcttaa
     3481 tttagatgta cctattagca taaattatca ctcctataaa gttaaagact tcttaaatac
     3541 ttaccaaaaa tatctattga aatcttttta atcccataaa tatcataaat aaaatcacta
     3601 aaactaagag ttttgaaata atttaaaata acaaaaaatt ttgaattaaa acaattattt
     3661 aatttattat accatataat ttaagttatt atgttgattt aaaacctatt tacactaatt
     3721 atctaaatat ctctttattt ttataatctt ttatgactta tttatatttt tcatttttat
     3781 aaaaaaacaa taattaagaa tataactata ttctacatgt aaaaattttt ttatttaaac
     3841 tcaattttct gataatttga taatttttca aaatttatag ttgactttta ttttttactg
     3901 tattaaacta attactatac aaaacagaaa acaaaatttt caaaattatt aaattaaaag
     3961 gagaggtaaa tatgaagact ttattaaaca aacaagtacg attttttagt agccaattta
     4021 gttagggttt gtacctaagt taagacaaat tgtcataaca tagatacaag ccccttagga
     4081 ttatgatttt taaggattgt atctatgttg gctatagtaa ttgttgttaa agtttttatt
     4141 ttatcatcat aatatagagc cacatggatt atactgtgtg gcttattcga atttttgcca
     4201 tacagttata tatactgtgt ggttttttta tatcaaaatc attttttaaa atcaaattta
     4261 aaaaaccatt taaaatattt tcaaaggggt gttttattta tgtcaggtat tatatctgta
     4321 atgacgcaaa gtttaatttt atcgattatg gcactggggg tttatataac ttacaaaatc
     4381 ttagattttc cagatatgtc tgctgatggt agctatacaa tgggtgcttc tattgtagca
     4441 ttttctctta ctaatggtat ttctcctgta gtagcaactt taatggctat cttatgtggt
     4501 tgtactgctg gtcttgttac agggattctt cacattaagt ttaagatatc taa
//
LOCUS       DAMKNB010000158         4539 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.164, whole genome shotgun sequence.
ACCESSION   DAMKNB010000158 DAMKNB010000000
VERSION     DAMKNB010000158.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4539)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4539)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4539
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.164"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            216..1691
                     /locus_tag="PC494_003557"
     CDS             216..1691
                     /locus_tag="PC494_003557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
                     /protein_id="HDF3914008.1"
                     /translation="MDSEFANAVELSYECAPLLESLKEYSEKDIACFDVPGHVKNRGV
                     AILNKYLGESLMKMDINSSPTMDNVSAPNGIIKNAQDLLAQAYMADEAFFITNGTTQA
                     IHAMILSVIKPGEKVLLPRNIHKSVINALILCGGIPIFIQPEFDEKLGISLNITLEKV
                     RTEIEKDCNIKALFFLNPTYYGVCADLESIIELCHKNNVLVLVDEAHGAHFPFHLDLP
                     PSAISLGADMVAVSIHKTGGALTQSSALLLNRDNVSFEKVLQSINMLQSTSASYLLMA
                     SIDGARVNLVENGEKQLSKALNLSRYAKSKLNKIDGIKVLSTEILKQKGVKFIDETKL
                     CINVKELNLTGFEVYDLLYKNFSIQVELGDSYNILALVSIGTNKSDIDRLVKALSIIA
                     KIYRKESTLNEFNMVQINPIIKLNPREAFYAPKESVEINSCIDRICGESIMAYPPGIP
                     IIAPGELITEEIMEYIIFLKNSNAYLTDVQDKNLDRILVIK"
     gene            1778..2191
                     /gene="speD"
                     /locus_tag="PC494_003558"
     CDS             1778..2191
                     /gene="speD"
                     /locus_tag="PC494_003558"
                     /EC_number="4.1.1.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosylmethionine decarboxylase"
                     /protein_id="HDF3914009.1"
                     /translation="MKFETLGRHILVEYYNCDENVLKDPRLIENFMNDSALNAKATIV
                     DSVFHHFNPWGVSGAVIIAESHLTIHTWPEYGYAAADFFTCGDIDPWKSFELLEQLLK
                     SERSESTEIPRGLTTKIKKYSKKDLGKITHKPEAV"
     gene            2221..3072
                     /gene="speE"
                     /locus_tag="PC494_003559"
     CDS             2221..3072
                     /gene="speE"
                     /locus_tag="PC494_003559"
                     /EC_number="2.5.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyamine aminopropyltransferase"
                     /protein_id="HDF3914010.1"
                     /translation="MELWYTEEWTENVRFSIKVNKHLFEGKSQFQRIDVFDSDEFGKF
                     LTIDGLMMVTYKDEFIYHEMITHVPMATNLNIKKVLVIGGGDGGTVRELSCYPQIEKI
                     DMVEIDKMVVDVSKEYMDICSCKLDDKRVSLYFEDGVNFVKCAHDKSYDLIIVDSTDP
                     IGPGEGLFSTDFYKDCYRILTDDGILVNQSESPYFDFNAKEMKRANKKLKQIFPISEV
                     YQAHIPTYPSGHWLFGFASKKLNPVKNQDRNGWEKLSLKTKYYNSDIHLGSFMLPQYV
                     KEMLDEE"
     gene            3062..3940
                     /gene="speB"
                     /locus_tag="PC494_003560"
     CDS             3062..3940
                     /gene="speB"
                     /locus_tag="PC494_003560"
                     /EC_number="3.5.3.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="agmatinase"
                     /protein_id="HDF3914011.1"
                     /translation="MKNNFYHRNTFMSMNKNYEESNLIVFGVGFDGTTSNRPGARFAS
                     SSMRKEFYGLETYSPFLDLDLEDYNICDYGDLEISVGSTEQVLKEIYQETYKIVRDSK
                     VPFMIGGEHLVTLPAFKAVHEKYNDIYVIHFDAHTDLREEYNNSKNSHATVIKRIWDI
                     VGDNKIFQFGIRSGTKEEFKFATEEKHTYMEIGGIDTFENIVNMLNGKNIYLTIDLDV
                     LDAAVFPGTGTPEPGGVNYREFQEIFKIIKNSNINIVGCDIVELSPDYDTTGVSTVIA
                     CKILRELCLIISDKIK"
     gene            complement(4120..4320)
                     /locus_tag="PC494_003561"
     CDS             complement(4120..4320)
                     /locus_tag="PC494_003561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000809131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HDF3914012.1"
                     /translation="MKNGIVKWFNNEKGFGFISVEGEDDVFVHFSAIQNDGYKTLEEG
                     EKVSFDITQGNRGPQAENVNRI"
BASE COUNT         1811 a          502 c          769 g         1457 t
ORIGIN      
        1 aaattaatat aaacaacaaa aaattaaaaa gtttataaat attgatatag ctaatgtata
       61 tgtttttgag taacttcaaa aaaacacttg taaaaatgct gagatgttaa tataataaat
      121 atcatgagtt taataaaagt aaaaataaaa aatagaaata ataaataata aatattaaaa
      181 atatttgaat atagagagga gatgaatttg aaatcatgga tagcgagttt gcaaatgcag
      241 ttgaattaag ctatgagtgt gctccattat tagagtcgtt aaaggaatac tcagagaaag
      301 atatagcttg ttttgatgtg cctggacatg taaaaaatag aggtgtagct atattaaata
      361 aatatctagg tgaaagtctc atgaaaatgg atataaattc atcaccaact atggataatg
      421 tatctgcgcc aaatgggatt ataaaaaatg cacaagattt gctagcacaa gcatatatgg
      481 ctgatgaggc attctttata acgaatggca caactcaagc aatacatgca atgattttga
      541 gtgttataaa accaggtgaa aaagtattac ttccaagaaa tatacataaa tcagtaataa
      601 atgcgttaat actttgtgga ggaataccaa tatttataca accagaattt gatgaaaaac
      661 taggtataag tttaaatatt actcttgaaa aagttagaac agagatagaa aaagattgta
      721 atataaaagc attatttttc cttaatccaa cttactatgg agtttgtgca gaccttgaga
      781 gtattataga actatgccat aaaaataatg ttttagtgtt agttgatgaa gctcatggtg
      841 cacattttcc atttcattta gatttacctc cttctgcaat aagtttggga gctgatatgg
      901 tagctgtaag tatacataaa actggaggag cattgacaca atcttcagca ctcttattga
      961 atagagataa tgtaagtttt gaaaaggttc ttcaatcaat caatatgcta caatcaacat
     1021 cagcatctta tttgcttatg gcaagtatag atggtgctag agttaatcta gttgagaatg
     1081 gtgaaaagca actgtcaaaa gcattaaatc tatctaggta tgcaaaatct aaattaaaca
     1141 aaattgatgg aataaaagtt ttatctacag aaatattgaa acaaaaaggt gttaaattta
     1201 tagatgaaac aaaattgtgt ataaatgtaa aagaattaaa tttgactgga tttgaagtat
     1261 acgatttatt atataaaaat ttttcaattc aagtagaatt gggagattca tataatatac
     1321 tggcacttgt gtccattgga acaaataaat cagatataga tagattagta aaagcacttt
     1381 ctataattgc aaagatttat agaaaagaat caacattaaa tgaatttaat atggttcaaa
     1441 taaatccaat tattaaactt aatccaagag aagcttttta tgcaccaaag gaaagtgtag
     1501 aaatcaattc atgtatagat agaatttgtg gagaatcaat aatggcatat ccaccaggta
     1561 taccgattat tgctccagga gaattgataa cagaagaaat tatggagtat attattttct
     1621 taaaaaatag caatgcatat cttacagatg tacaagataa aaacttagat agaatattag
     1681 taataaaata aattacttta ttttgcaagg gcaagtattt gttaagtaga gtttatcaaa
     1741 tagaacttat taaaagtata aaggagttgg ggttgaaatg aaatttgaaa cactaggaag
     1801 acatatacta gtagaatact ataattgtga tgaaaacgta cttaaagacc cacgtcttat
     1861 agaaaatttt atgaatgatt cagcattaaa tgcaaaagcg acaattgtgg attctgtatt
     1921 ccaccatttt aatccttggg gggtttcagg agctgttata attgctgaat ctcatttgac
     1981 aatacataca tggcctgaat atggttatgc agcagcggat ttttttactt gtggtgatat
     2041 agacccatgg aaaagttttg aattattaga gcaactttta aagtctgaaa gaagcgagtc
     2101 tacagaaatt ccaagaggct taactacaaa aattaaaaaa tattcaaaaa aagatttagg
     2161 taagattact cataaaccag aagcagtata aaacatacaa gagaaagtga ggattattat
     2221 atggaacttt ggtatacaga agaatggaca gaaaatgtaa gattttctat aaaagtaaat
     2281 aaacatctat ttgaaggaaa gtctcaattt caaaggatag atgtatttga tagtgatgaa
     2341 tttggaaaat ttctaacaat agatggatta atgatggtaa catataaaga tgaatttata
     2401 taccatgaga tgataactca tgttcctatg gctacaaatt taaacataaa gaaagtatta
     2461 gtcataggtg gaggtgatgg aggtacagta agagaattaa gctgttatcc tcaaatagaa
     2521 aagattgaca tggttgaaat agataaaatg gttgtagatg tatctaagga gtatatggat
     2581 atatgctcat gtaaattaga tgataaaaga gtgagtttat attttgaaga tggtgttaat
     2641 tttgttaagt gtgcacatga taaatcatat gacctgataa tagtagattc aactgaccca
     2701 ataggaccag gcgaagggct tttctcaact gatttttata aggattgtta tagaatactg
     2761 actgatgatg gaattttagt aaatcaaagt gaaagtccgt attttgactt taatgctaaa
     2821 gagatgaaaa gagctaataa aaagttaaaa cagatatttc caatatcaga agtttatcaa
     2881 gcacatatac caacatatcc atctggtcac tggttgtttg gatttgcttc aaaaaaactt
     2941 aatccagtaa aaaatcaaga tagaaatgga tgggagaaat taagtttaaa aactaaatat
     3001 tataatagtg atatacattt aggttcgttt atgttacctc aatacgtgaa ggagatgcta
     3061 gatgaagaat aatttctatc ataggaacac ttttatgagt atgaacaaaa attatgaaga
     3121 atctaatctt atagtatttg gtgttggatt tgatggaact acttctaaca gacctggggc
     3181 tagatttgca agtagctcta tgagaaaaga attttacggt cttgagacat atagtccttt
     3241 tttagatttg gatttagagg attataatat atgtgattat ggagatttag aaattagtgt
     3301 tggaagtaca gaacaagtct taaaagaaat ctatcaagag acatataaga ttgttagaga
     3361 ttcaaaggta ccctttatga ttggaggaga gcatttagtt acattaccag cctttaaagc
     3421 agtacatgaa aagtacaatg atatatatgt aattcatttt gatgcccata ctgacttgag
     3481 ggaagaatat aataatagta aaaattctca tgcaacagta attaaaagaa tatgggatat
     3541 tgtaggtgat aataaaatat ttcaatttgg tataaggtct gggacaaaag aagaatttaa
     3601 atttgctaca gaagaaaaac acacatacat ggaaatagga ggaatagata cgtttgaaaa
     3661 tatagttaat atgctaaatg gaaagaatat ttatctaact atagatttag atgtattgga
     3721 tgcagctgtg tttccaggaa caggtacacc agaacctggt ggtgtaaatt atagagagtt
     3781 tcaagagatt tttaagatta taaaaaactc taatataaat atagttggtt gtgacattgt
     3841 agagttaagc cctgattacg atacaacagg tgtatcgaca gttatagctt gtaaaatctt
     3901 aagagagtta tgcttaataa tatctgataa aattaaatag agtattttat ataaatagta
     3961 tatattataa tataagaagt tattttaaaa aagttagttt aagtttgacg cttttctaaa
     4021 gtaacttctt atttttgtaa ttaaaaataa atataataaa caacaaaaaa gagccctcga
     4081 tagctccttt tctaaaatat atatatttaa attaaataat tatattctat ttacgttttc
     4141 agcttgaggt cctctattac cttgagttat atcaaagcta accttttcgc cttcttctaa
     4201 agttttgtat ccatcatttt gtatagctga gaaatgtacg aaaacatcat cttctccctc
     4261 tacagatatg aacccaaatc ctttttcatt gttaaaccat tttactattc cgtttttcat
     4321 tataagaaaa cctccgcatt attaaaaaat acaaactaaa aaaataagtc tgttctatta
     4381 atataacata aattttaaat aaaagcaaat aaaattttta aaaaaattaa ttacttttag
     4441 aatttaataa aaattgttaa attatacagt gataagtatt gtaaaatttg acgaaaatgt
     4501 aaatgtagat aataaattta atatcaaaaa atgtaacaa
//
LOCUS       DAMKNB010000159         4518 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.165, whole genome shotgun sequence.
ACCESSION   DAMKNB010000159 DAMKNB010000000
VERSION     DAMKNB010000159.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4518)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4518)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4518
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.165"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            227..1039
                     /locus_tag="PC494_003562"
     CDS             227..1039
                     /locus_tag="PC494_003562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mrp/NBP35 family ATP-binding protein"
                     /protein_id="HDF3914013.1"
                     /translation="MADCNSCPSKGNCNSQSNCSIENNPNNKFGKIIGVMSGKGGVGK
                     STVTALLANKLNKMGYKVGILDSDITGPSIPRLMGVKNVKAYSDGSYIYPVENSNNIK
                     VMSINLMIDDENEPVVWRGPLLGGVVKQFYTDVLWEELDYLLIDMPPGTGDVALTVMQ
                     SIPISGIVMVSVPQDLVSMIVSKAVNMAKKMNINVLGVIENMSYIQCPDCSKKIKLFE
                     GESTEKFLDDLDLELLGELPMTKEIIDITHNGVTEISDDLDSILTNVVEKIK"
     gene            complement(1128..1319)
                     /locus_tag="PC494_003563"
     CDS             complement(1128..1319)
                     /locus_tag="PC494_003563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3914014.1"
                     /translation="MERLMELIERKFLKDVELLELEDIENVIECKMTQPYNAHYNEYL
                     VKVKNGDEVEEYFVYLKHR"
     gene            1590..1829
                     /locus_tag="PC494_003564"
     CDS             1590..1829
                     /locus_tag="PC494_003564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF3914015.1"
                     /translation="MNYNLIKVIFSLFKKKSGYTFTNFLNKVRVEKSKKYILKKDLSI
                     LDVAVLIGFNSQNYYSIIFKKFNNFTPIEYKNIYN"
     gene            2138..3757
                     /locus_tag="PC494_003565"
     CDS             2138..3757
                     /locus_tag="PC494_003565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
                     /protein_id="HDF3914016.1"
                     /translation="MNIVISLIGGLGLFLYGMSLMGEGLQKSAGDKLKKIIELLTSNV
                     VMGVLVGTVVTGIIQSSSATTVMVVGFVNAGIMNLSQAIGVIMGANIGTTVTAQLVSF
                     NLEGIAPIALGIGILFYLFTSNQKTKHLSEILIGFGILFTGMEFMKDAVAPLAEYKAF
                     TDALLYFSKNPVLGILAGFAITGIVQSSSASMGMLIALASQGILPLSSALPILYGDNI
                     GTCVTSLLSSVGASRNARRAAVMHLSFNVIGTIIFMLVLNKPISAIVTHFDPTDTARQ
                     IANAHTLFNLTNVIILLPFSKYIVKLANRLIPIKETESEIVNNTKYLDERMFSTPSIA
                     LGNTVQEVVRMGHKATNSLEHSIAGFLNKSNEDINKAFESEKVVNKLQKDILNYLLKL
                     SKEPLRDDERFRTDLLFNTVNDIERVSDHAENIAELAMSVKEMNISFSDSAIREIYEI
                     YNKTITNFKDALIVLDVKDFELANKVLEVENEVNYLEKTFRNSHMIRLNNGSCTIDAG
                     VLYLDLLTNLERISDHSTNIVKQVLKLKQKI"
     gene            4131..4325
                     /locus_tag="PC494_003566"
     CDS             4131..4325
                     /locus_tag="PC494_003566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HDF3914017.1"
                     /translation="MINYMVEIIYSEKISEVENMLKIENIQYEFTSRDGFIFFGFYDM
                     TDAYRFETLCSDEKIRFKRI"
BASE COUNT         1689 a          518 c          628 g         1683 t
ORIGIN      
        1 tttctatata tttatatgac taagttctat aactaaattg aaataatcac tttttcaaga
       61 atgttataat ttttttattg tattcttttt gctatagtct atgaataaat caatagaaaa
      121 tcttctaagt tgcttttaaa taatgacttt atggttcaat tgtactaaaa tagtatatgt
      181 aggttacaaa taatctaata aatattaaag tttggaggta atagatatgg cagattgtaa
      241 ttcatgtcca tcaaagggaa attgtaatag tcaatcaaat tgttctattg aaaataaccc
      301 taacaataaa tttggaaaaa taattggtgt tatgagtggg aagggtggag ttggaaaatc
      361 aactgtaact gctttacttg ctaataagct aaacaaaatg ggatataagg ttggtatatt
      421 agactcagat ataactggac caagtattcc tagacttatg ggtgtaaaaa atgtaaaagc
      481 ttattctgat ggctcttata tttaccctgt agaaaactca aataacataa aagtaatgtc
      541 tataaacctt atgatagatg atgaaaatga acctgttgtt tggagaggac ctttacttgg
      601 aggggttgta aagcaatttt atactgatgt actttgggaa gaattagact atttattaat
      661 agatatgcct cctggtactg gagatgttgc cttaacagtt atgcaatcta ttcctataag
      721 tggaatagtt atggtttcag tacctcaaga tttggtatct atgattgtat caaaagctgt
      781 taatatggct aaaaaaatga acataaatgt ccttggagtt attgaaaata tgagttatat
      841 ccaatgtcct gattgttcta aaaaaatcaa gttatttgaa ggagaatcta ctgaaaagtt
      901 tttagatgat ttagacttag agcttttagg agaacttcct atgactaaag aaattataga
      961 tattactcat aatggagtta cagaaattag tgatgattta gattcaatat tgactaatgt
     1021 tgttgaaaaa attaaataaa taaaaatttt ataattttat atttatcaaa aaaagaggct
     1081 tgtatttatt ttataatcat acaaataaat ataaacctct tttatgttta tctatgtttt
     1141 aaatacacaa aatattcttc tacttcatct ccatttttta cttttactaa atattcatta
     1201 taatgagcat tatatggctg tgtcattttg cattctatta cattttctat gtcttctaat
     1261 tctaaaagtt ctacatcctt taaaaatttt ctttctatga gttccattaa tctttccata
     1321 atatatcctc acttccccta taattaagat aaactatata tcctcttaat gcagagttta
     1381 tctgtttatt atattatatc caatatatta cagtttctaa catcattcat aaattatttt
     1441 aacaaataga gattgatttt ttaataaata tgccttgata aaatgaaaca tagaccaact
     1501 cttagtttta tgtaaagaaa acttaaagaa aactataaat tatattcaca aaaattactc
     1561 agaagatata acagtaagta atatatgtaa tgaattacaa cttaataaaa gttatttttt
     1621 ctttgtttaa gaaaaaaagt ggatatactt ttactaattt tttaaataaa gttagagttg
     1681 aaaaaagcaa aaagtatata ttaaaaaaag acttgtctat tttagacgtt gctgtactaa
     1741 ttggattcaa tagtcaaaat tactatagta taatttttaa aaagtttaat aactttacac
     1801 caattgaata taaaaatatt tataactaaa aaatatcatt ctaaaaggat gttatttttt
     1861 tacatatttt ttacaattat agttaattct ttgttaaatt gtttgtacat aaaatactaa
     1921 aaatctaagt tcaagtattt aaattgctat atatcataaa ttttctaaaa ttaacaacaa
     1981 cttaaaaatt taacattctc ttaacgtata cttaacaaaa cattaatatt tttattgaca
     2041 aaatttgtta ttctatatta tggaaacaat aaattttagt taataaagtt tataattcag
     2101 ataaaaaaat tattaatttc ttaagggagg aaatatcgtg aatatagtaa ttagccttat
     2161 cggtggactt ggactttttc tttacggaat gagtttaatg ggagaaggtt tacaaaaatc
     2221 agcaggagac aaattaaaaa aaattattga actcttaaca agtaatgttg ttatgggtgt
     2281 actggtaggt acagtcgtta caggtattat acaaagttca agtgctacta ctgttatggt
     2341 tgtaggattt gtaaatgcag gtataatgaa tctaagtcaa gctattggtg taataatggg
     2401 ggcaaatata ggtactacag ttactgctca attagtttca tttaatcttg aaggaattgc
     2461 accaattgct ttaggtatag gtattttatt ctatttattt acatcaaatc aaaaaacaaa
     2521 gcatttatct gagatactta taggtttcgg tatattattt acaggaatgg agtttatgaa
     2581 agatgcagta gctccacttg ctgaatataa agcattcact gatgcacttt tatattttag
     2641 taaaaatcct gtattaggta tattggcagg atttgccata actggtattg ttcaaagttc
     2701 aagtgcatct atgggtatgt taatagcact agcttctcaa ggaatacttc ctctatcatc
     2761 tgctttacct attctttatg gagataatat aggtacttgt gttacttcac ttttatcaag
     2821 tgttggtgca agtagaaatg ctcgacgtgc agctgtaatg catttaagtt ttaatgtaat
     2881 tggtacaata atatttatgc ttgttttaaa taaacctata tcagccatag ttactcattt
     2941 tgacccaact gatacagcta gacaaatagc aaatgcacat actttattta atcttacaaa
     3001 tgttataata ttattaccat tttctaaata catagttaaa ttagcaaata gacttatacc
     3061 tattaaagaa actgaatcag aaatagtaaa taatactaag tacttagatg aaaggatgtt
     3121 tagcactcca tctatagcac ttggtaatac tgtacaagaa gttgtaagaa tgggtcataa
     3181 agctacaaac tctttggaac attcaattgc aggattttta aataagagca atgaagatat
     3241 taataaagct tttgagtcag aaaaagttgt caataagtta cagaaagata tattgaacta
     3301 tttgttaaaa ctttctaaag aacctcttag agatgatgaa cgctttagaa cagatttgct
     3361 ttttaatact gtaaatgaca ttgaaagagt ctctgaccat gcagaaaata tagctgaatt
     3421 ggccatgagt gttaaggaaa tgaacattag tttttctgat agtgcgataa gagaaatata
     3481 cgaaatatac aataagacaa ttactaattt taaggatgcc ttaatagttt tagatgttaa
     3541 agattttgag ttagcaaata aagttttaga agttgaaaat gaagtaaatt atttagaaaa
     3601 aacttttaga aattcacata tgattagact aaataatgga agttgtacaa ttgatgctgg
     3661 tgtactttat cttgacttac ttactaatct agaaagaatt tctgaccact caacaaatat
     3721 agtaaaacaa gtactaaaac ttaaacaaaa aatatagtga ttatttttat atataatctt
     3781 aatcaatgag aagtaagaag ctatagataa tgcttatatc atttatggct tcttattttt
     3841 tatgtaatac tcaaattttt atagtattct cttattatta aacagtttct gcctagaata
     3901 ttccatatat atatgacttc tttcataaaa cttgaactgc ccataaataa agtcacaagt
     3961 atacataact attttttaat caattataac caatatttgt tttatttatc ttcattttaa
     4021 ttcttcattc aataatgtaa taatattatt ttttatttgg atactattat atcatctaaa
     4081 tatgttatta tatatttgga tattttcata ttaataggag ggattctaca atgataaatt
     4141 atatggtaga aattatatat agcgaaaaaa taagcgaagt agaaaacatg ttgaaaattg
     4201 aaaatataca atatgaattt acttctcgtg atggctttat attttttggt ttttatgata
     4261 tgacagacgc atatagattt gagactttat gttcagatga aaaaattcga tttaaaagaa
     4321 tataatagat aaaaaagtac atatttctaa actatttgtt tttcaaattt aggttgtgtt
     4381 ttaatgtagt gttgatatta taaacaattt taataataaa aaagtaggga cattatatta
     4441 atatgctcct actttttact catacttatt aatattattt atcaaaatta ccctacaaac
     4501 tggaatttat cattcttt
//
LOCUS       DAMKNB010000160         4463 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.166, whole genome shotgun sequence.
ACCESSION   DAMKNB010000160 DAMKNB010000000
VERSION     DAMKNB010000160.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4463)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4463)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4463
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.166"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     misc_binding    87..321
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            371..1390
                     /gene="pheS"
                     /locus_tag="PC494_003567"
     CDS             371..1390
                     /gene="pheS"
                     /locus_tag="PC494_003567"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HDF3914018.1"
                     /translation="MQEKLLALREAALAEIKEAQSIESVESLRVKYLGKKGEITAILK
                     EMGKLSAEERPVVGKVANEVRENIELSINSKKEEINAIEKERKLKEEVIDVTQPGKVL
                     KVGKKHPITQIIDEVTDIFIGMGFSIAEGPEVETVENNFDALNAPKDHPSRDMSDTFY
                     INDGVLLRTQTSPVQVRTMRSQELPIKVIAPGRCFRSDSPDATHSPMFHQIEGLVVGK
                     DVTMAEFKGTMDIFVEKLFGSDIKTKFRPHNFPFTEPSAEVDVTCFKCGGKGCPMCKY
                     EGWIEILGSGMVHPNVLRNCGIDPEVYSGFAFGVGVERLAMLKYEIDDIRLLFENDMR
                     FLNQF"
     gene            1407..3800
                     /locus_tag="PC494_003568"
     CDS             1407..3800
                     /locus_tag="PC494_003568"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HDF3914019.1"
                     /translation="MLVSLKWLRDYVDIDMDVKEFADKMTMSGTKVETIDYYGEEIEN
                     ILVGKILEIKQHPNADKLVVTKVDIGDKVVQIVTGATNISEGDYIPVAVNGSKLPGGV
                     EIKQTDFRGELSDGMMCSAAELGIDEHYIEEYKRGGIYILDHEDSYELGKDIKDVLGL
                     KDALIDFELTSNRPDCKCMMGIAREAAATIGTKVKYPEIEVKESDEEIDFKVEIDNPD
                     LCRRYVARMVTDVKIEPSPYWMQRRLTEAGVRPISNIVDITNFVMLELGQPLHAFDIN
                     QVETGRIVVRNAKDGEKLVTLDDVERTLDKDMLVITNGEKSLGLAGVMGGANSEITSN
                     TKTVLFESANFKPENIRMTAKKVGIRSEASSRNEKDLDPNLAEIAANRAAQLVEMLGA
                     GKVLKGVVDVYPNKPEPKKLVVNPQRINHLLGVDVPMEQFVGILESLEFKCNLVANDK
                     LEIDVPSFRTDMEQEADVWEEIARIYGFENIPSVQLEGNTTAGIKTSKQKFMDALKDN
                     STAVGLNEILTYSFVSPKGVDKIRVPEGNAKRNFVKLLNPLGEETSVMRTTLIPNMLD
                     VLSTNVSHKIEEVSAFECGHIFIPQDSELPKEENRMCVGMYGKDVDFFALKGTIETIL
                     VNVGFKGYEIEPQDNNTTFHPGRCAKIVYNNKYVGTLGELHPDVIENYNLGQRVYVAE
                     IDIDFVFDNSDRTKNYVPLPKYPSTSRDIALIVKDDVFVKQIEDIIKENGQGLVESYK
                     LFDVYKGSQIEAGYKSIAYSITYRSKDKTLTDEDVAKVHDKILSELSEKLNANLRSN"
     gene            3825..4415
                     /gene="zapA"
                     /locus_tag="PC494_003569"
     CDS             3825..4415
                     /gene="zapA"
                     /locus_tag="PC494_003569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HDF3914020.1"
                     /translation="MNKVMVKIHGAEYPMVGDKSEKFMISIADFVDKEMDKITRQNPK
                     LSLSVAAILTALNISDLLFECSDENEKLIKANEELSKKVGASNEELQLEIKSLKLTIA
                     EKEAENREAETKMKELIEIIENKKQEIFELSNTTEGSRAELDAYKNKIEELSTQLEEA
                     NERATIAENLASEFQNKAYDLQLKCTGLNNDAKNVE"
BASE COUNT         1755 a          519 c          919 g         1270 t
ORIGIN      
        1 aattaattat gtattggata tatattaaaa atagtcacat aatttgaatg gaaatgatat
       61 aatactaaaa taaacaatat aatattgtaa atgcaatgaa agaggaaagt attttgatta
      121 aacttagtaa agagataaac acctaggctg ggagtgtttt ctaagaggtc atgagaagtt
      181 ccctctggag taacagagct gaaattttac agtaggcttt gacgtcaaaa acgcgttaag
      241 tttgttagag gtggtttgat gatttttaaa ttgttaaact actagggtgg taccgcgaaa
      301 ctatagcctt tcgtccctag acagggattg aggggctttt tttatacaaa aaaacgaaag
      361 ggtgatatgt gtgcaagaaa aattacttgc tttacgtgaa gcagctttgg ctgaaataaa
      421 agaagcacaa agcatagaaa gtgtagaaag tttaagagtt aagtacttag gaaaaaaagg
      481 tgagataact gccatactta aagaaatggg taaattatct gctgaagaaa gaccagtagt
      541 tggtaaggtt gccaatgagg taagagaaaa cattgaactt agcataaatt ctaaaaaaga
      601 agaaataaat gctattgaaa aagaaagaaa attaaaagag gaagtgatag atgttactca
      661 accaggaaaa gttttaaagg ttgggaagaa gcatccaata actcaaatta tagatgaagt
      721 aacagatata tttatcggaa tgggattctc tatagcagaa gggccagaag ttgagactgt
      781 tgaaaacaac tttgacgcat taaacgctcc taaagaccat ccatcaagag atatgagcga
      841 tacattctat atcaatgatg gggtattact tagaactcaa acatctccag ttcaagtaag
      901 aactatgaga agtcaagagt taccaataaa agtaattgca ccaggtagat gttttaggtc
      961 agactcgcca gatgctacac actcaccaat gttccatcag atagaagggc ttgttgttgg
     1021 aaaagatgtt actatggcag aatttaaagg aactatggat atcttcgttg aaaaattgtt
     1081 tggttctgat atcaaaacta agtttagacc tcacaacttc ccatttacag aaccaagtgc
     1141 agaggttgat gttacttgtt tcaaatgtgg tggtaaaggt tgcccaatgt gtaaatatga
     1201 aggttggata gaaatattag gttcaggtat ggttcatcca aatgtgctta gaaattgtgg
     1261 aatagaccca gaagtttaca gtggatttgc atttggagtt ggggttgaaa gacttgcaat
     1321 gcttaaatat gaaatagatg atattagatt attattcgaa aatgatatga gattcttaaa
     1381 tcaattttaa ttaggagggt atgtagatgt tagtatcttt aaaatggctt agagactatg
     1441 ttgatataga catggatgta aaagagttcg ctgataaaat gacaatgtca ggaactaaag
     1501 ttgaaacaat agattattat ggtgaagaaa tagaaaatat attggttgga aagattttag
     1561 aaataaaaca acatccaaat gctgataagt tggttgtaac caaagtagat attggagata
     1621 aagttgttca aatagttaca ggagctacaa atatatcaga aggagattat attccagtag
     1681 ctgtaaatgg ttctaagtta cctggaggag ttgaaatcaa acagactgat ttcagaggtg
     1741 aattatcaga tggtatgatg tgttcagcag ctgaactagg tatagatgaa cattacattg
     1801 aggagtataa aagaggtggt atatatattt tagaccacga agattcttat gaattaggaa
     1861 aagatataaa agatgtttta ggattaaaag atgctttaat agattttgaa ttaacttcaa
     1921 acagacctga ttgtaaatgc atgatgggta tagctagaga agcagctgca actataggaa
     1981 caaaagtaaa atatcctgaa atcgaagtaa aagaaagtga cgaagagata gatttcaaag
     2041 ttgagataga taatccagat ttatgtagaa gatatgttgc tagaatggtt acagatgtaa
     2101 aaatagaacc ttctccatat tggatgcaaa gaagacttac agaagcagga gtaagaccta
     2161 taagtaacat agtcgatata acaaacttcg taatgttaga gcttggtcaa ccacttcatg
     2221 cttttgatat aaatcaagta gagactggaa gaatagtagt aagaaatgct aaagatggag
     2281 agaaacttgt aacattagat gatgttgaga gaacattaga caaagatatg ctagttataa
     2341 caaatggaga aaaatcactt ggtttagctg gtgtaatggg tggtgctaac tcagaaataa
     2401 cttctaatac gaagactgta ctttttgaaa gtgccaattt caaaccagaa aacataagaa
     2461 tgacagctaa aaaagttggt attaggtcag aagcatcttc aagaaatgaa aaagacttag
     2521 accctaatct tgcagagata gcagcaaata gagctgcaca gcttgttgaa atgttaggag
     2581 caggaaaagt tttaaaaggt gttgtagatg tatatccaaa taaaccagaa cctaaaaaat
     2641 tggtagtaaa tcctcaaaga attaaccatc tattaggtgt agatgtacca atggagcagt
     2701 ttgtaggaat tttagaatca ttagagttta aatgtaattt ggtagctaat gataaattag
     2761 aaatagatgt accaagcttt agaacagata tggaacaaga agctgatgta tgggaagaaa
     2821 tagctagaat ttatggattt gagaatatac cttctgtaca attagaagga aatacgacag
     2881 caggaattaa aacttcaaaa caaaaattca tggatgcttt aaaagataat tcaactgctg
     2941 taggattaaa tgaaatatta acatattcat ttgtaagccc taagggagta gataagataa
     3001 gagtaccaga aggtaatgca aagagaaatt ttgttaaatt acttaaccca ttaggagaag
     3061 aaacttctgt aatgagaact actttaatac caaatatgtt agatgtttta tcaactaatg
     3121 tatctcataa aatagaagaa gtatctgcat ttgagtgtgg acatatattc atcccacaag
     3181 attcagaatt acctaaggaa gaaaatagaa tgtgtgtagg tatgtatggt aaagatgttg
     3241 acttctttgc actaaaagga actatagaaa ctatacttgt aaatgtcgga tttaaaggtt
     3301 atgaaattga acctcaagat aataatacta ccttccaccc tggtagatgt gctaaaatag
     3361 tgtataataa taaatatgta ggtacattag gtgaattgca tccagatgtt atagaaaact
     3421 acaatctagg tcaaagagtt tatgtcgctg aaatagatat tgactttgta tttgataatt
     3481 ctgatagaac aaagaattat gtgccattac caaaatatcc atctacatca agagatatag
     3541 ctcttattgt taaagatgat gtatttgtaa aacaaataga agatataata aaggaaaatg
     3601 gtcaaggatt agtagaaagc tacaagttat ttgatgttta caaaggttct caaatagaag
     3661 ctggatacaa gtcaattgca tattcaataa cttatagaag taaagataaa actctaacag
     3721 atgaagatgt agctaaggtg catgataaga tattaagtga attaagcgaa aaattaaatg
     3781 ctaacttaag atcaaattaa caactaatgt cgggggaggt taggatgaac aaagtaatgg
     3841 ttaaaatcca tggcgctgaa tatccaatgg ttggagacaa atcagagaag tttatgatta
     3901 gtattgctga ttttgtagac aaagaaatgg ataaaataac acgtcaaaac ccgaaattga
     3961 gcttatcagt tgctgcgata ttaactgcat taaatatatc agacctttta tttgaatgtt
     4021 cagatgagaa tgagaagttg attaaagcta atgaagaatt gagtaagaag gttggagcat
     4081 ctaatgaaga gcttcaatta gaaatcaagt ctttaaagct tacgatagca gaaaaagaag
     4141 cagaaaatcg tgaagctgaa actaagatga aagagttaat tgagattata gaaaataaaa
     4201 agcaagaaat attcgaactt agtaatacga cagaaggttc tagagcagag ttagatgctt
     4261 ataaaaacaa gattgaggag ttaagtactc aacttgaaga agcaaatgaa agagctacta
     4321 tagctgaaaa cttagcttct gagtttcaaa acaaagctta tgatttacag ttaaaatgta
     4381 cagggttaaa taatgatgca aaaaatgtgg aataaactaa aagatttgct gtctcttgtt
     4441 ttttgagaca gcttctttta atg
//
LOCUS       DAMKNB010000161         4460 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.167, whole genome shotgun sequence.
ACCESSION   DAMKNB010000161 DAMKNB010000000
VERSION     DAMKNB010000161.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4460)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4460)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4460
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.167"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            complement(100..645)
                     /locus_tag="PC494_003570"
     CDS             complement(100..645)
                     /locus_tag="PC494_003570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH peroxidase"
                     /protein_id="HDF3914021.1"
                     /translation="MKKFVCTVCGYIHEGDAAPAQCPVCKVGADKFEEMKGEKNWADE
                     HRIGVAQGVDEEIIEGLRANFVGECTEVGMYLAMSRQADREGYPEVGEAYKRIALEEA
                     EHAAKFAELLGEVVVADTKENLRVRVDAEYGATDGKLKLAKKAKELGLDAIHDTVHEM
                     CKDEARHGKAFLGLLNRYFGK"
     gene            complement(763..2586)
                     /locus_tag="PC494_003571"
     CDS             complement(763..2586)
                     /locus_tag="PC494_003571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF3914022.1"
                     /translation="MNLSTGNQKVSRLKKKEKPKDFKKTFKRIFMYFKKDKKITRFIF
                     LLLIIDSIISTVIPYTIGKVVDIIDIDTYSKSIFLKGIIILLSFYIIEFSVKLSKGIC
                     TARLSQSIVKEMRSNLFLKFKNLPITFFDKSSTGDIMSRVTNDVDNISTGISNSLVQL
                     ITGILNILMTFIMMFVLSPILTFCSVILIPIVMFVSNFIAKRTRVFFKQQQVELGKLN
                     AHIEEMISNINVVKSFNYERKSVNDFKEVNDRLLNISLKSQIYTSLLMPIMNVISNIG
                     FATICIIGGILASKDIITIGVIASFLSYVRQFTRPLNELANLFNTLLSAIAGCERVFE
                     IIDEQEEQEVHNMFKSEINDNKDGNLNSHFVKGEIELKDVSFSYDSKKKILDNINLKI
                     KSGTSNAIIGETGSGKTTIINLITNFYHIDEGSIFLDGKDIYSINRNYLRTCFGVVPQ
                     EGYIFNDTVMENIRYGNLEATDEEVIYASKIANAHKFIVKMREGYSTVLSDRGEDLSE
                     GQKQLISIARAVLKNAPILILDEATSNIDIATEAKIQEAINNLTYGKTSIIIAHRLST
                     ISNCDNIIVLENGRIVESGNHKELIKLKGHYYRNILLTQGK"
     gene            complement(2599..4374)
                     /locus_tag="PC494_003572"
     CDS             complement(2599..4374)
                     /locus_tag="PC494_003572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF3914023.1"
                     /translation="MRYFKKYIKKYIVLFLTAVFFLTLEAFCDLAQPTIMAKIIDIGV
                     SNKNLDYILSTGAIMIGITFLGAIFAIIRSVISARVSQNFSYDLRQDVFEKINTYSLK
                     QIDKFGRASLITRITNDINQMQQFVNGMMRVFIKSPIMCIGSLIIAIKLNLKMSIIIL
                     IAVLIIFIIILLNMKIGYRLFKNVQESTDKVNSKLRQFLSGIKVVKLFCRYDYENQSF
                     EELNDELFKNSRKATTMMSFFRPTITIIINVSIIIILLIGRHLIYSGEIKIGIIVAYV
                     NYMTRILTSLIMISHVFNVFVRAKASYERISEVLVDENEEVIEREESLDVGEKDLKFV
                     NCDIIFENVDFSYNKNTDEKILKNVSFKIEEGQNIGVIGQTGSGKTSLVNLIQKLYII
                     DKGDIKIGGRSIYSISEESLRTRIGVVFQNSSVFGKSILENVVMGNRDICKEDVVKSC
                     EIANANQFITKLENTYDEVLFQRGKNLSGGQRQRITIARAIAKKPQILILDDCFSAMD
                     INTETIIRKNIKEYISNLREKESKKCTVITISQKISSIIDCDKILVLDEGEVVGFATH
                     EDLLVSSPIYKKIFALQNLVSEDVN"
BASE COUNT         1462 a          792 c          392 g         1814 t
ORIGIN      
        1 ttagaaataa aaaataaagt acaaataatt aaaaaatatc tcactcataa ctttaaaaat
       61 tataagtgag atactcctaa aatctacttt atattaaatt tattttccaa aatatctatt
      121 taataatcct aagaatgctt taccatgtct agcttcatct ttacacattt catgtactgt
      181 atcatgtata gcatctaatc ctaattcttt tgctttctta gctaatttta attttccatc
      241 agttgcacca tactcagcat caactctaac tcttaagttt tcttttgtat ctgcaactac
      301 aacttctcca agaagttctg caaatttagc agcatgttca gcttcttcaa gagctattct
      361 cttataagct tctcctactt ctggataacc ttctctatca gcttgtctac tcattgctaa
      421 atacattcct acttctgtac actcaccaac aaagttagct cttaatcctt cgattatttc
      481 ttcatctaca ccttgagcta ctcctattct gtgctcatca gcccaatttt tttcgccttt
      541 catttcttca aatttatcag ctccaacttt acatactgga cattgtgctg gtgcagcatc
      601 tccttcatgt atatatccac atactgtaca aacaaatttc ttcataatta ctttcctcct
      661 aaattttata tatcaaatta aattttttat ttattaagtt agtctatata tacccgcacc
      721 atataccttt aaacaatttt tttaaaagtt ttttctaaat acttattttc cctgtgtcaa
      781 taatatgttt ctataataat gtccctttaa ttttatcaat tctttatgat ttcctgattc
      841 cacaattcta ccattttcta aaactattat attatcacaa tttgatatgg tacttaatct
      901 atgagctata attatacttg tctttccata agttaaatta tttattgctt cttgaatttt
      961 agcttctgtt gctatatcta tgttacttgt agcctcatcc aaaataagta ttggagcatt
     1021 ttttaatact gctctagcaa tacttattaa ttgtttttga ccttcactta aatcttcacc
     1081 cctatccgat aatacagtac tatatccttc acgcatttta actataaatt tatgtgcatt
     1141 tgctatttta ctagcatata taacttcttc atcagtagcc tccagatttc cataccttat
     1201 attttccata actgtatcat tgaatatata accttcttgt ggaactactc caaaacaagt
     1261 tctcaaatag tttctgttaa tagagtatat atccttacca tctaaaaata tacttccttc
     1321 atctatatga taaaaatttg taattagatt tataattgtt gtttttccac ttcccgtctc
     1381 tcctatgatg gcatttgatg tgccagattt gatttttagg tttatattat ctaaaatttt
     1441 cttttttgaa tcataagaaa aacttacatc tttaagctca atttctccct ttacaaaatg
     1501 agagtttaaa ttaccatctt tattatcgtt aatctcactt ttaaacatgt tatgcacttc
     1561 ttgctcttct tgttcatcta taatttcaaa aactctttca catccagcta tggctgaaag
     1621 taatgtatta aatagatttg ctaattcatt taaaggtctt gtaaattgtc ttacataact
     1681 taaaaaacta gctataaccc ctatggttat aatatcttta gatgcaagaa tgcctcctat
     1741 aatacatata gttgcaaatc ctatattact aatcacattc ataataggca ttaaaagaga
     1801 agtgtaaatt tgcgatttaa gggaaatatt tagaagtcta tcattgactt ctttaaaatc
     1861 atttacagat tttctttcat aattaaaaga ttttactaca tttatgtttg atatcatttc
     1921 ttcaatatgt gcatttagtt ttcccaactc aacttgttgt tgcttaaaaa aaactctagt
     1981 tctctttgca ataaaattac tcacaaacat tactatcggt attaatatta cactgcaaaa
     2041 ggttaaaatt gggcttaata caaacatcat aataaaagtc atcaatatgt ttaagattcc
     2101 tgtaattaac tgtactaatg aatttgatat tcctgtactg atattatcaa catcatttgt
     2161 cactctactc ataatatctc cagtagaact tttatcaaaa aaggttattg gtagattttt
     2221 aaattttaaa aataaattac ttctcatttc tttaactata ctttgagata atctagctgt
     2281 acatatcccc ttagacagtt taactgaaaa ctcaattata taaaatgaaa gtaaaataat
     2341 tattcctttt aagaaaatgg attttgaata agtatcgata tctattatgt caactacctt
     2401 tccaatagta tatggtatta cagttgatat aattgaatca attattaata gcaaaaaaat
     2461 aaatctagta atcttcttat cttttttaaa gtacataaaa attcttttaa acgttttttt
     2521 aaaatcttta ggcttttctt ttttctttaa tctactgacc ttctgatttc cagtacttaa
     2581 attcaatata cttcctcctt aatttacatc ttcacttact aaattttgca acgcaaaaat
     2641 ttttttataa attggagaac taaccagtaa atcttcatgt gtagcaaatc caaccacctc
     2701 accctcatcc aagactaaaa tcttatcaca gtcaattata gaactaatct tttgtgaaat
     2761 agttattaca gtacatttct tactttcctt ttctcttaaa ttacttatat actcttttat
     2821 attctttctt ataattgtct ctgtattaat atccattgca ctaaaacaat catcaagaat
     2881 taatatttgt ggttttttgg ctatagctct agctatagta attctttgtc tctgtcctcc
     2941 tgataaattt ttaccccttt ggaataaaac ttcatcataa gtattttcga gttttgttat
     3001 aaattgattt gcatttgcta tttcacatga ttttacaaca tcttctttgc atatatctct
     3061 atttcccata actacattct ccaatatact ttttccaaac acactactat tttgaaatac
     3121 tacacctatt cttgtcctta aactttcttc agaaatactg tatatactac gtcctccaat
     3181 cttaatatca cctttatcaa ttatatataa tttttgaatt aaatttacta aagaagtctt
     3241 tcctgaacca gtttgaccaa tcacaccaat attttgacct tcttctattt taaaggatac
     3301 gttttttaat attttttcat ctgtattttt gttatacgaa aaatctacat tttcaaaaat
     3361 tatatcacaa tttacaaact ttaaatcttt ttctccaaca tctaaacttt cttctctctc
     3421 aattacttct tcattctcat caaccaaaac ctcacttatt ctctcataag atgcttttgc
     3481 cctaacaaaa acattaaaaa catgtgaaat cattataaga gatgttaata ttctagtcat
     3541 atagtttaca taagcaacta taatcccaat tttaatttct cctgaataaa ttaaatgcct
     3601 tccaattagt aatattatta ttatggaaac attaatgatt attgtaattg tcggtctaaa
     3661 aaatgacatc atagttgtag cttttctact atttttaaaa agttcatcat ttaactcttc
     3721 aaagctttgg ttctcataat cgtatctaca aaatagttta actactttta ttccacttaa
     3781 aaactgtctt aattttgaat ttactttatc tgtactttct tgtacatttt taaataatct
     3841 ataccctatc ttcatattaa gcaatattat aataaatata attaaaactg caattagaat
     3901 aattattgac atctttaaat ttaattttat agctataatt aaacttccta tacacattat
     3961 tggtgacttt ataaaaactc tcatcattcc attaacgaat tgttgcattt gattgatatc
     4021 attagtaatt cttgttatta atgaagctct accaaattta tctatttgtt ttaatgagta
     4081 tgtatttatc ttttcaaata catcctgtct taaatcataa gaaaaattct gagaaactct
     4141 tgccgagatt acacttctta ttattgcaaa tattgcacct aaaaaagtta tacctatcat
     4201 tatagctcct gttgatagta tgtagtctaa gttcttattt gaaaccccta tatctattat
     4261 ttttgccatt atagttggtt gagctaaatc acaaaaagct tccaatgtta aaaaaaatac
     4321 tgctgttaga aataatacta tatatttttt tatgtatttt ttaaaatacc tcattcaatc
     4381 atcccttcat agaattttct cattaccaaa agtatatcat aatggctaat ttaattgatt
     4441 atatcaatta taaatatttg
//
LOCUS       DAMKNB010000162         4440 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.168, whole genome shotgun sequence.
ACCESSION   DAMKNB010000162 DAMKNB010000000
VERSION     DAMKNB010000162.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4440)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4440)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4440
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.168"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            135..1733
                     /locus_tag="PC494_003573"
     CDS             135..1733
                     /locus_tag="PC494_003573"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative manganese-dependent inorganic
                     diphosphatase"
                     /protein_id="HDF3914024.1"
                     /translation="MSLLVFGHKNPDTDSICSAISLAHLKNKLGIKATAYALGDIRKE
                     AKYALDYFKVDAPEILDNVRIQVRDLNYDKVVPLTPTSSILEAYNLMDEKNVKTLPVT
                     YDDGTFAGIITMKEIAKNLLHQHFTTIHTSLSNICKNLNGTILVDCGEDIKGRVVTLS
                     FGMETLIETLKEGDIAIVGDRYDSIEYAIDTKVKLLILTNHTEISKDLLALAKINGVS
                     VVSVESDNYKTSNVINQCSFLDSIEATENLITFKEDDYMDEIKEIMLETNFRSYPILD
                     DDNKFLGLVSKGHLLNPSKKNVVLVDHNEYAQSADGIEQANIVEIIDHHKLGGISTDV
                     PMSFRVMPVGCNSTIIYQMYKENNVEIPYEIAGLLLSAILSDTLLFKSPTTTDIDKKA
                     CEELSKIAKVDMEKYAMDMFKCGTSLDEYTIEEIVNMDFKEFNMSGHRVGIGQVFTLD
                     IDSIFAKKDEFLSYINSTDYDKLILAVTDIIKEGSYLIYKAEDSLIANAFGVEGVQGT
                     FAPGVVSRKKQLVPNLTTAIKNFK"
     gene            complement(1972..4017)
                     /gene="bclA1"
                     /locus_tag="PC494_003574"
     CDS             complement(1972..4017)
                     /gene="bclA1"
                     /locus_tag="PC494_003574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-like exosporium glycoprotein BclA1"
                     /protein_id="HDF3914025.1"
                     /translation="MRNIILYLNDDTFISKKYPDKNFSNLDYCLIGSKCSNSFVKEKL
                     ITFFKVRIPDILKDKSILKAELFIHIDSNKNHIFKEKVDIEIKRISEYYNLRTITWND
                     RVSMENIRGYLPVGISDTSNYICLNITGTIKAWAMNKYPNYGLALSLNYPYQILEFTS
                     SRGCNKPYILVTFEDRIIDNCYPKCECLPIRITGPMGPRGATGSTGPTGVTGPTGSTG
                     ATGSIGPTGPTGNTGATGSIGPTGVTGPTGSTGATGSIGPTGVTGPTGNTGVTGSIGP
                     TGATGPTGNTGVTGSIGPTGVTGPTGNTGEIGPTGATGPTGVTGSIGPTGATGPTGEI
                     GPTGATGATGVTGSIGPTGATGPTGATGVTGEIGPTGEIGPTGATGPTGVTGSIGPTG
                     ATGEIGPTGEIGPTGATGPTGVTGSIGPTGATGPTGATGEIGPTGATGPTGNTGVTGE
                     IGPTGATGPTGNTGVTGEIGPTGATGPTGVTGEIGPTGNTGATGSIGPTGVTGPTGAT
                     GSIGPTGATGATGVTGPTGPTGATGNSSQPVANFLVNAPSPQTLNNGDAITGWQTIIG
                     NSSSITVDANGTFTVQENGVYYISVSVALQPGSSSINQYSFAILFPILGGKDLAGLTT
                     EPGGGGVLSGYFAGFLFGGTTFTINNFSSTTVGIRNGQSAGTAATLTIFRIADTVMT"
BASE COUNT         1335 a          788 c          666 g         1651 t
ORIGIN      
        1 atttatgtaa gaaataaatt ttatataata ttttttcact aaattttttt ctttttacaa
       61 caaatactca ctaccttttg atataatatt tttatcaatt attattatat tcaagttttg
      121 aaaggagtat taaaatgagt ttattagttt tcggacataa aaatccagat acagattcaa
      181 tatgttctgc aatttcatta gcacatttaa agaacaaact aggaataaaa gcaacagctt
      241 atgctttagg agatatcaga aaagaagcta aatatgcctt ggattacttt aaggtagatg
      301 cacctgaaat tttagataat gttagaatac aagttagaga tttaaattat gataaagtag
      361 tacctttaac accaacttca tctatattag aggcttataa ccttatggat gaaaaaaatg
      421 ttaaaacact acctgtaact tatgatgatg gaacttttgc tggtatcatt actatgaaag
      481 aaatagctaa aaatctactt catcaacact ttacaactat acacacatca ctatcaaaca
      541 tttgtaaaaa ccttaatggt actattcttg tggactgtgg tgaagatata aaaggtagag
      601 tagtcacttt atcatttgga atggagactc taatagagac tttaaaagaa ggagacatag
      661 ctattgttgg agatagatat gatagtattg aatatgctat tgatacaaaa gttaaacttt
      721 taatacttac taatcataca gagatttcaa aagatttgct agctcttgct aagataaatg
      781 gagtgtctgt tgtttctgtt gaaagtgaca attataaaac ttctaatgta ataaatcaat
      841 gtagtttctt agactctata gaagctacag aaaatttaat tacattcaaa gaagatgatt
      901 atatggatga aataaaagag attatgctag aaacaaactt cagatcttat ccaatattag
      961 atgatgataa taagttttta ggtttagttt caaaaggtca tctattaaac ccatctaaaa
     1021 agaatgttgt tttagttgac cataacgaat atgctcaaag tgctgatgga attgaacaag
     1081 caaacatagt tgaaataatt gaccatcata aacttggtgg tatttctact gatgttccta
     1141 tgtcatttag agttatgcct gttggatgca atagtactat aatttatcaa atgtacaaag
     1201 aaaataatgt tgagatacct tatgaaatag ccgggcttct tttatctgct atattatcag
     1261 atacattatt atttaagtct ccaacaacaa ctgatataga taagaaagct tgtgaagaat
     1321 taagtaaaat agcaaaagta gacatggaaa aatacgctat ggatatgttt aaatgcggta
     1381 cttctttaga tgaatatact atagaagaaa tagtaaatat ggactttaaa gaatttaata
     1441 tgagtggaca tagagttggt attggacaag tatttacctt agacatagac tctatatttg
     1501 ctaaaaaaga tgagttttta tcttatataa attcgactga ttatgacaaa ctaattcttg
     1561 cggttacaga tataatcaaa gaaggttctt atttaatcta taaagcagaa gacagcttaa
     1621 ttgctaacgc atttggtgtt gaaggtgttc aaggtacatt tgcaccaggt gttgtatcaa
     1681 gaaaaaaaca attagtccct aatttaacta ctgcaatcaa aaattttaaa taatataaaa
     1741 tttttaaata acgaaaactg tctcaaatct atatttgaga cagtttttta ttatatatat
     1801 atatattgat aataaagtta aataaaaatc cataaattta aaatttttat gaatatattt
     1861 tattattatt gttattttat tcattctaaa ataggtaaaa ctcaatatat aaaaatactt
     1921 ttgtcattta aataaagcct aaatagtttt taagattatt ttagacacgt tttaagtcat
     1981 aacagtatca gctattctaa atatcgtcaa agtagccgca gttcctgctg attgcccatt
     2041 tcgtatccct actgttgtag atgaaaaatt atttattgta aaagtagtcc caccaaataa
     2101 aaaaccagca aaatatccag aaagtactcc tccgcctcct ggctcagtag taagccctgc
     2161 caaatctttt cctcctaaaa ttgggaatag gatagcgaaa gaatattgat ttatacttga
     2221 tgaacctggt tgtaatgcta ctgaaactga tatataatac acaccatttt cttgtactgt
     2281 aaacgtacca tttgcatcta ctgttatact tgaactattt cctattattg tttgccaacc
     2341 tgttatagca tctccattat ttagtgtttg tggagatggt gcatttacga ggaagttagc
     2401 aactggctga gaggaattgc ctgttgctcc tgttggacct gttgggcctg ttactcctgt
     2461 cgctcctgtt gctcccgttg gtcctatact tcctgtcgct cctgttggac ctgttactcc
     2521 cgttggccct atacttcctg tcgctcctgt atttcctgtt ggccctattt ctcctgtcac
     2581 tcctgttggg cctgttgctc ccgttggtcc tatttctcct gtcactcctg tatttcctgt
     2641 cggacccgtt gctcccgttg gtcctatttc tcctgttact cctgtatttc ctgttggacc
     2701 tgttgctccc gttggtccta tttctcctgt cgctcctgtt gggcctgttg ctcccgttgg
     2761 tcctatactt cctgtcactc ctgttgggcc tgttgctcct gttggtccta tttctcctgt
     2821 tggtcctatt tctcctgtcg ctcccgttgg tcctatactt cctgtcactc ctgttgggcc
     2881 tgttgctccc gttggtccta tttctcctgt tggccctatt tctcctgtca ctcctgtcgc
     2941 tcctgttgga cctgttgctc ctgttggtcc tatacttcct gtcactcctg tcgctcctgt
     3001 tgctcccgtt ggtcctattt ctcctgttgg tcctgttgct cctgttggtc ctatacttcc
     3061 tgtcactcct gttggacctg ttgctcccgt tggtcctatt tctcctgtat ttcctgttgg
     3121 gcctgttact cctgttggtc ctatacttcc tgtcactccc gtatttcctg tcgggcctgt
     3181 tgctcccgtt ggtcctatac ttcctgtcac tcccgtattt cctgtcggac ctgttactcc
     3241 tgttggtcct atacttcctg tcgctcctgt acttccggtt gggcctgtta ctcccgttgg
     3301 ccctatactt cctgttgctc ctgtatttcc ggttgggcct gttggtccta tgcttcctgt
     3361 cgctcctgta cttccggttg ggcctgttac tcccgttggt cctgtacttc ctgtcgctcc
     3421 tcttggtccc attggacctg taattctaat tggaagacac tcacatttag gataacaatt
     3481 atctataatt ctatcttcaa atgttacaag tatatacggt ttgttacaac ctctactaga
     3541 tgtaaattca agaatctgat aagggtaatt taaagataaa gctaacccat aattaggata
     3601 tttattcatt gcccatgctt ttatagttcc cgtaatattt aaacaaatat agttggatgt
     3661 atcacttatc ccaactggta aatatcccct aatattttcc atagacactc tatcattcca
     3721 tgttatagtt cgtaaattat aatattcact tattctttta atttcaatat ctactttttc
     3781 tttaaaaata tgattcttat ttgaatcaat atgaataaat aactctgctt ttaatatact
     3841 tttgtctttt aatatatctg gtattctcac tttaaaaaaa gtaatcaact tttcttttac
     3901 aaaactattt gaacatttac ttcctattaa gcaataatct aaattactaa agtttttatc
     3961 tggatatttt ttagatataa aagtatcatc atttaaataa agtataatat ttctcattta
     4021 taatccctcc attttgggtc tatatcatac tatgtttaaa atacatgctt agttacaata
     4081 taattaaaat ttatagtatt aaatttttat ataataatgc tgatttctac aaaaaaagaa
     4141 catgtcatta gaaatttcta atagcatgtt ctttttcatt attatatatt acactttaaa
     4201 ttattccttg actggcttag ctggtgtaaa ctaaaccagt ctttctaaaa tattaagcac
     4261 ttttttctta ttatgttttt taggatttat tgtctatatt attgtaaacc aaagttataa
     4321 aattgtaaat agaatatatt accataacaa tatcttttta taagtaaaaa ttataaaaaa
     4381 ccttattttt attaaataga ataaataaaa taagtttaaa aaatactgaa ataagtgttt
//
LOCUS       DAMKNB010000163         4434 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.169, whole genome shotgun sequence.
ACCESSION   DAMKNB010000163 DAMKNB010000000
VERSION     DAMKNB010000163.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4434)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4434)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4434
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.169"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            13..546
                     /locus_tag="PC494_003575"
     CDS             13..546
                     /locus_tag="PC494_003575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor"
                     /protein_id="HDF3914026.1"
                     /translation="MTEVIIVNDARIISQIKAGKKELFDTLIKKYYDSIYCYCYRHVD
                     NKMTAQDLTQDVFVTVINNIENYKHYGKFENYLYVIAKNKCKDFWKKKQPIYLESLDK
                     EISNQELSDIENKMFIKEALTKLPELEFEVIILRYYHDLKFKDIAKIMESSVSVTKYR
                     MSRALKKLELYLEGGKL"
     gene            543..1304
                     /locus_tag="PC494_003576"
     CDS             543..1304
                     /locus_tag="PC494_003576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3914027.1"
                     /translation="MNNKEIKRSLQKYKVPKYDSSALEKTIKTIHELTLSNTYKRMNN
                     KDFFISQIGFIRKRTWIMQFIILCTICIFLFSTSADSNSFYNTLSLISIASPLFVLTN
                     IEELTKVYNSSILEIEFSTKNTLHKIIATRMLIFGISDLLFMIIILVSAKQIIDVNIL
                     YIIIYILVPFNLMCIGCMEIINRNKGKHTNYYCMIYGISLVLLIVTLSNFRDNLYQFE
                     AINQWLIVFLVTAVTLIYEIRKTWRHLCSFENIII"
     gene            1342..2208
                     /locus_tag="PC494_003577"
     CDS             1342..2208
                     /locus_tag="PC494_003577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF3914028.1"
                     /translation="MELSVERLTKQYNNKIIVDKIDFKLNEGIYGFLGENGAGKTTLM
                     RMICGILSPTSGEVKVDGKNNLDMGEDFRDMIGYLPQNFGYYPDFTAKEFMLYIASLK
                     GLMPSYAKRKTQELLEMVGLSEVINKKIRTFSGGMKQRLGFAQTLLNDPKILILDEPT
                     AGLDPKERVKFRNLISEFSKEKIVILSTHIVSDVEYIADKILIMKKGRFVLTGSVEEV
                     TSKIKDKVWKCVVNENEIDYMSDRYCLANIHHSGGVANLRIVSDIKPHDNACNLKPTL
                     EDLYLYCFNEVL"
     gene            2229..3470
                     /locus_tag="PC494_003578"
     CDS             2229..3470
                     /locus_tag="PC494_003578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HDF3914029.1"
                     /translation="MSTLIKFELKKIIKRKSTIAVILGSLFLSIILFALMPIQEKAND
                     ESGKEYRGLQAIELKKQQSKLNEGYITDKKVKNSIRDYQKMFNNPNNIVTNESGLSDF
                     KPDIYWKFFYPNKTFYNFIIESYSKPNDFNPEVIKSMPLENEINFYKFRNEKVNTILN
                     MEYPEGNYTQKEKDFWLSKNKDIKEPYLNGYYQGWEYFLLARDLLIFTIMAVCISIAS
                     VFSGEYQSGADSVVLTSKYGKTKVITAKIISSFLFGTIIFTINTIVSIGILLLSFGTD
                     GWNLPLQLTTSSIPYPYTFLQAILLSVLTIYMVLIVLISFTLLLSSYMKSPFPVLITN
                     IILLFVPIFFKYSETNKLYNQILNVLPSNAISFSFTNYVDYKFGNLIIALPTMIIFTC
                     LVLTVVFLPFIKNNFKKHQVN"
     gene            complement(3694..4266)
                     /locus_tag="PC494_003579"
     CDS             complement(3694..4266)
                     /locus_tag="PC494_003579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDF3914030.1"
                     /translation="MFKKIVAMASSIIVSTICLTGCDFNSNDKKDESSSSKNLDKVTI
                     AEVTHSVFYAPQYAAITKGFFEDEGIKIDLINTQGADKTMAALISGEANVGLMGPEAS
                     IYVYNQNKNDYAVNFAQLTKRDGSFLVARKKMPNFSYNDLKGTEILGGRKGGVPLMTF
                     EYVLKEKGLTIGENLKAGNVNVRTDVQKSV"
BASE COUNT         1714 a          517 c          651 g         1552 t
ORIGIN      
        1 tcgttatata taatgacgga ggtgataata gtgaatgatg ctcggattat atcacaaata
       61 aaagcaggaa aaaaagaatt gtttgatact ctaataaaaa aatactatga tagcatctat
      121 tgttattgtt atcgccatgt agacaataaa atgactgcac aagatttaac tcaagatgta
      181 tttgtaacag ttataaataa tatagaaaat tataaacatt atggtaagtt tgaaaactat
      241 ttatatgtta ttgcaaaaaa caagtgtaag gatttttgga agaaaaaaca accgatatat
      301 ttagagtcat tagataagga gatatcaaat caagaattgt ctgatataga aaataaaatg
      361 tttataaaag aagctttgac taaattacca gaattagaat ttgaagtgat aattttacgg
      421 tattaccatg atttaaaatt taaggatatt gctaaaatta tggagtcaag cgtctctgtc
      481 acaaagtaca ggatgagtag ggcattaaaa aaactagaat tatatctgga aggaggtaaa
      541 ttatgaataa taaagaaata aaaagaagtc tacagaagta taaggttccc aaatatgatt
      601 cttcagctct tgaaaagact attaaaacta tacacgagtt aacgcttagt aatacttata
      661 aaagaatgaa taataaagac ttttttatat ctcaaattgg ttttataaga aaaagaactt
      721 ggattatgca atttataata ctatgtacaa tatgtatatt tttatttagt acatcagcag
      781 atagtaattc attttataat actttatcct tgatttctat agcatcacca ctttttgtgc
      841 tgacaaatat agaagaatta acaaaagtat ataatagtag tattttagag atagaatttt
      901 caacaaaaaa tacattacat aaaattattg ctactagaat gcttatattt ggaataagtg
      961 atttattgtt tatgattatt attttggtat ctgcaaaaca aatcattgat gtaaacattc
     1021 tgtatataat aatttatata ctagttcctt ttaacctaat gtgtatagga tgtatggaaa
     1081 ttataaatag aaataaaggt aagcatacaa attattattg tatgatatat ggtatatctc
     1141 ttgtattatt aatagttaca ctgagtaact ttagagataa tctatatcaa tttgaagcaa
     1201 taaatcaatg gctaattgtt tttctagtca cagcagtaac attaatatat gaaataagaa
     1261 aaacgtggag acatctttgt tcatttgaaa atattattat ctaagtaaaa aataagaata
     1321 cacagtatca ggaggaatag tatggagtta agtgtagaac gtttaacaaa acagtataac
     1381 aataaaatta tagtagataa aattgacttt aaattaaatg agggtatata tggattttta
     1441 ggagaaaatg gagcgggaaa aacaactctt atgagaatga tttgcggaat attaagtcct
     1501 acatctggag aagtaaaggt ggatggtaaa aataatttgg atatgggaga agattttaga
     1561 gatatgattg gataccttcc tcaaaacttt ggatactacc cagattttac tgccaaagaa
     1621 tttatgctat atatagcatc attaaaagga ttaatgccta gctatgcaaa gagaaaaaca
     1681 caagaattat tagaaatggt aggattatca gaggtaatta ataaaaaaat aagaacattt
     1741 tctggaggta tgaagcaaag gctaggattt gctcaaacac tacttaatga cccaaaaatt
     1801 ttaatattag atgagccaac agcagggcta gaccctaaag aacgagttaa atttcgcaac
     1861 ctaatttcag aattttctaa ggaaaagatt gttatattgt ctactcatat tgtgtctgat
     1921 gtagagtata ttgcagataa aattttaata atgaaaaaag gaagatttgt tttaactggc
     1981 tcagtagaag aagtaacttc aaagataaaa gataaggtat ggaaatgtgt ggtcaatgag
     2041 aatgaaatag attatatgtc tgatagatat tgtttagcaa atatccatca ttctggtgga
     2101 gttgcaaatc ttagaattgt aagtgatata aagccacatg acaatgcatg caatttaaaa
     2161 ccaacattag aagatttata tttatattgt ttcaacgaag tactataaat atacataagg
     2221 agataggtat gtctacatta attaaatttg agttaaaaaa aataataaaa agaaagtcta
     2281 caatagcagt tattttagga agtttattct taagcatcat tctttttgca ttaatgccaa
     2341 ttcaggaaaa agctaatgat gaaagtggaa aagagtatag gggtttacag gctattgagc
     2401 taaaaaagca acaatctaaa ttaaatgagg gatacataac agataaaaaa gtaaaaaact
     2461 caatcagaga ttaccaaaaa atgtttaata atccaaataa cattgtaaca aatgagtctg
     2521 gattatcaga ttttaagcca gatatttatt ggaaattctt ctatccaaat aaaacttttt
     2581 ataattttat aatagagtca tatagtaaac caaatgattt taacccagaa gtaattaaat
     2641 caatgccatt agaaaatgaa attaattttt ataaatttag aaatgaaaaa gtaaatacaa
     2701 tattaaatat ggaatatcca gagggaaatt acacacagaa agaaaaggac ttttggttat
     2761 ctaaaaataa ggatataaag gagccttatt taaatggata ttatcaaggg tgggaatatt
     2821 ttctattggc aagagattta ctgattttta ctataatggc tgtctgtata agtatagctt
     2881 ctgtattttc aggagaatac caatctggtg ctgattcagt agtattgact tctaaatatg
     2941 gaaaaacaaa agttataaca gctaaaataa taagttcctt cttatttggt acgattattt
     3001 ttacaataaa tacaattgta tctattggca tacttctttt atcttttgga actgatggct
     3061 ggaatttacc actacaactt acaactagtt caattccata cccatataca tttttacagg
     3121 caatattact aagtgtgtta actatctata tggtattaat agtattaatt agttttacac
     3181 ttttattatc gtcttatatg aaatctcctt ttccagtttt aattacaaat ataatattgt
     3241 tatttgtacc aatatttttc aaatacagtg aaacaaataa gttgtataat caaattctca
     3301 atgttttacc atcaaatgct atttcatttt catttactaa ttatgtagat tataaatttg
     3361 gtaatttaat aatagcttta cctacaatga ttatttttac atgcttagtt cttacagttg
     3421 tttttttacc ttttattaaa aataatttta aaaaacatca agttaactaa aatatatatt
     3481 ataaaaagaa ggtgtcttaa aatgaacttt ttagcttatt aggcactctt ctttgtatta
     3541 atttaaatat attttagtat tagattaaat atgttttcat cattttaaca atgaaaaaga
     3601 gccttatctc tattttgaga tagctcttat aaagttaaat attaaattga taactataaa
     3661 atatgtagtt tgaatttata atttgtgtta taatcatact gatttttgta catcagttct
     3721 tacattaaca ttgcctgctt ttagattttc tccaatagta agaccttttt cttttagaac
     3781 atattcaaaa gtcattagtg gaactccacc ttttctacca cctaatattt cggttccttt
     3841 taaatcattg taagagaaat taggcatttt tttcctagca actagaaaac taccatctct
     3901 ttttgtcaat tgagcaaagt tcactgcata atcgtttttg ttttgattat atacatatat
     3961 agatgcttca ggacccatta aacctacgtt tgcttcacct gaaatcaaag ctgccatagt
     4021 tttatctgca ccttgggtat ttataaggtc aatctttata ccttcatctt caaagaatcc
     4081 tttcgtaata gcagcatact gtggagcata aaaaacagag tgagtaactt ctgctatagt
     4141 tactttatcc agatttttag acgaagaaga ttcatctttt ttgtcattag agttaaaatc
     4201 acatccagtt agacatattg tacttacaat gatagagctt gccattgcga ctattttttt
     4261 aaacataata aatacctccc ataagacata cgaatagtat atagtattaa aaatttattg
     4321 tagttgttac aaaaatgtat ctatgcttat aatatttcta caaaaactta ataataattt
     4381 tcagttttat gtttagtttt tttagtaatg tgtaatattg gataaattat attg
//
LOCUS       DAMKNB010000164         4159 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.170, whole genome shotgun sequence.
ACCESSION   DAMKNB010000164 DAMKNB010000000
VERSION     DAMKNB010000164.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4159)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4159)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4159
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.170"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            171..1574
                     /locus_tag="PC494_003580"
     CDS             171..1574
                     /locus_tag="PC494_003580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HDF3914031.1"
                     /translation="MEKKKIGLWSLVFMNVSALYGIRWIAKSTASSFGLGLGAIPMWL
                     LFSFIYFVPGALICAELASTYQKGDGGLYDWVKEAFGEKYGFLVSWLNWTAKIFWYSS
                     FLTFLAVNVSYTIGNPALADNKMFVLILSLIIFWALSLIATKGISFTKIFTNTGALGS
                     TIPSAILIIFSFVAVFVLKKHDIASTYTIASMTPKLNMDAFVAISAIMFGLAGAETAA
                     NFITEIDKPEKNFPKAILISAGIVASLYVLGSIAITMIIPPDQITASKGVLDALSAVC
                     ASLGIGSWLVQLIAFGIAFSVLGAIVLYIASPIKMLFGSVKKGIFPDSLVEVNEHKIP
                     SKAVILQAIIVTIILLVTTLMPSVDAIYNVLVTMTALTALFPYVLLYASYIKLRKERP
                     DEIRPYTMAKSTSTCLGLAKMVLVVTVVGILLSAAPVMPTFAENVIYEIEMIGGGLLV
                     ILSGLWLWNRYEKKTAK"
     misc_binding    1665..1905
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            1948..2646
                     /locus_tag="PC494_003581"
     CDS             1948..2646
                     /locus_tag="PC494_003581"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HDF3914032.1"
                     /translation="MNVIGIIGAMDEEVSILVDLMDIRETIKKASLEFYKGILEGKNV
                     VLVKCGIGKVNSALCAQILISEFKVDAIVNTGVAGALNEKLDVNDIVISTDAIQYDVD
                     TTAFGDPKGVIPRMKTSVFKADERLIDAAYKSSVEEVKTHKVLKGRVVTGDKFINSKE
                     LKEELVNDFGGYCGEMEGGAIAHVCYLNNTPFVIIRAMSDKADGSADVTYDVFVHDAA
                     NNSKDIVLNMLKSI"
     gene            2669..3670
                     /gene="trpS"
                     /locus_tag="PC494_003582"
     CDS             2669..3670
                     /gene="trpS"
                     /locus_tag="PC494_003582"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HDF3914033.1"
                     /translation="MSEKKVIFSGAQPSGKMTLGNYLGAIKNWTELQDNYDCYYSIVD
                     LHAITVPQDPKVLRANTIELLAQYIACGLDPEKNTIFIQSHVKEHVELMWVLNTMTYM
                     GELSRMTQFKDKSQKSEANLNAGLFTYPVLMAADILLYQTDLVPVGDDQKQHLELARD
                     LANRFNNRFSPTFVVPEGYYPKGGARVMSLQEPTKKMSKSDSNENAFILLADDSDSIK
                     RKIKRSVTDSLGVVKYNDEQPGIKNLIDIYSNLSKKSVEEIVNMYEGKGYGIFKEDVA
                     EVVSEALRPIREKYVDLLNNKDYLEKIYSMGAEKAEKQARKTLRKVYKKVGFIERRY"
BASE COUNT         1563 a          459 c          739 g         1398 t
ORIGIN      
        1 atttatcatt tttaataaga tttgatttca aagtatttaa ggtttattat taaaactgtt
       61 tttgaatatg caaatatttt gaaaaatatc agtttaataa taatgaatct attttattaa
      121 ttttgaaatt aaatttaaaa taattaatag agaggggaaa ttaaattagg atggaaaaga
      181 aaaaaatagg cctatggagt ttggtattta tgaatgtatc agctttatat ggtataagat
      241 ggatagctaa atctacagca tcaagctttg gtttaggatt aggtgcaata cctatgtggt
      301 tattattctc atttatatac tttgtaccag gagctttaat ttgtgctgaa ttagcttcta
      361 catatcaaaa aggtgatgga ggtctttacg attgggttaa ggaagccttt ggagaaaagt
      421 atggattttt agtttcttgg ttaaactgga cagctaaaat attttggtat tcttcatttt
      481 taactttctt agcagtaaat gtttcttata caataggaaa tccagccctt gctgataata
      541 agatgtttgt acttatatta tctttaataa tattctgggc attatctctt atagcaacta
      601 aaggaataag ttttacaaaa atatttacta atacaggtgc attaggttca acaataccaa
      661 gtgctatact tataatattt tcatttgtag cagtatttgt gttgaaaaaa catgatatag
      721 cttctacata cacaatagct tcaatgactc caaaacttaa tatggatgca tttgttgcta
      781 tatcagctat aatgtttggt ttagcaggag cagagactgc tgctaacttc ataacagaaa
      841 tagataagcc tgaaaagaac ttccctaagg caatattaat atcagctgga atagtagctt
      901 cattatatgt attaggctca attgcaataa caatgataat accaccagac caaattactg
      961 cttctaaagg tgtattagat gcactttctg ctgtttgtgc gtctttagga attggttctt
     1021 ggttggttca attaatagct tttggtatag ctttttcagt attaggagca atagttcttt
     1081 acatagcatc accaataaaa atgttatttg gtagtgttaa aaaaggaata tttccagata
     1141 gtttagtaga ggtaaatgaa cacaagatac cttctaaagc agttatactt caagcaataa
     1201 tagttactat aatactattg gtgactacat taatgccttc tgttgatgct atatacaatg
     1261 ttcttgtaac tatgacagca ttaactgcat tattcccata tgtattgtta tatgcttctt
     1321 atattaaact aagaaaagag agaccagatg aaattagacc ttatactatg gcaaaatcaa
     1381 caagtacttg cctaggttta gcaaaaatgg ttttagttgt aactgtagtg ggtatattat
     1441 tatctgcagc accagttatg cctacatttg ctgaaaatgt tatatatgag atagagatga
     1501 ttggtggagg tcttctagtt atattatctg gtctatggtt atggaataga tatgaaaaga
     1561 aaacagctaa ataaaatgta ttttaaaaat ttcttttgga tattataata tatagttgac
     1621 aatttatagt gtaaggaata ttataaaata aagaaattaa taaattaaat cctgagataa
     1681 gaaatagtaa ataaatatat ttttgcacag agaattaagg atgctgagaa cttaataaaa
     1741 agtatttatt gaatgggtct ttgaggagta aaatgaaatg taatttaata ttacagagta
     1801 tttgatatcg tgtatgcacg ttatagcata tattaagata tatatattca attttgagtg
     1861 tatataaatt taggtggtac cacggaaaat atatccgtcc tattgattta ggacggattt
     1921 tttaatatag aaaatttagg aggaaaaatg aacgtaatag gaattatagg tgcaatggat
     1981 gaagaagtta gtattttagt tgatttaatg gatattagag agactataaa aaaagctagc
     2041 ttagaatttt ataagggaat tttggaaggt aagaatgtag tgttagtaaa gtgtggcata
     2101 ggtaaggtta actctgctct ttgtgcccag atactaataa gcgaatttaa ggttgatgct
     2161 attgttaata caggtgttgc aggagcttta aacgaaaaac ttgatgttaa tgatatagta
     2221 atatcaactg atgctataca gtatgatgta gacactacag catttggaga ccctaaggga
     2281 gttataccaa gaatgaagac ttctgtattt aaagcagatg aaagacttat agatgctgct
     2341 tacaaatctt ctgtggaaga agtaaagact cataaagtat taaaaggaag agtagttaca
     2401 ggagataaat ttataaattc taaagaatta aaagaagaat tagtaaatga ttttggtgga
     2461 tattgtggag aaatggaagg tggagctata gctcatgtat gctatttaaa taatactcca
     2521 tttgtaataa taagagcaat gtctgataag gcagatggaa gtgctgatgt tacttatgat
     2581 gtatttgtac atgatgctgc caataactct aaagacatag ttttaaatat gttaaaatca
     2641 atataaatat ataaggaggt acaaaaaaat gagtgaaaaa aaagttatat ttagtggtgc
     2701 acagccatca ggcaaaatga ctttaggaaa ttatttagga gctataaaaa actggactga
     2761 acttcaagac aattatgatt gttattatag tatagttgat ttgcatgcaa taacagtacc
     2821 tcaagaccct aaagttttaa gagccaatac tatagaatta cttgctcaat atatagcttg
     2881 tggattagac ccagaaaaaa atactatatt tatacaatca catgtcaaag agcatgttga
     2941 acttatgtgg gtattgaata ctatgactta tatgggtgaa ttaagtagaa tgactcaatt
     3001 caaagataaa tcacaaaaga gtgaagcaaa tctaaatgca ggtttattca catatccagt
     3061 tcttatggct gctgacatat tgttgtatca aactgaccta gttccagttg gagatgacca
     3121 aaaacaacat ttagaattag ctcgtgattt agcaaataga tttaataata gattttcacc
     3181 tacttttgta gttccagaag gatactaccc aaaaggtgga gcaagagtga tgagtttgca
     3241 agagccaact aaaaaaatga gtaaatccga ttcaaatgaa aatgcattta tactattagc
     3301 agatgattca gattctataa agagaaagat aaaaagaagt gttactgatt ctttaggtgt
     3361 tgtaaaatac aatgatgaac aaccaggtat taaaaatcta attgatatat attctaattt
     3421 aagtaaaaag agtgtagaag agattgtaaa catgtatgaa ggaaagggtt atggcatatt
     3481 taaagaagat gtggctgaag tagtatcaga agctttaaga cctataagag aaaaatatgt
     3541 tgaccttctt aataataaag attatttaga aaaaatatat agtatgggag cagaaaaagc
     3601 cgaaaaacaa gctagaaaaa ctcttagaaa agtttataaa aaagttggat ttatagagag
     3661 aagatactaa ttattagcta tctttacttg ataaataaat tttaaagtta ttaaaaaggt
     3721 atatgatatg aaagagagag tctcaaagtg aacttttgtt catgaggcac tcttttttgt
     3781 atgaaataaa atatatttta atcatttcaa caatgaaaaa gaggattatc tctattttga
     3841 gacagcatct tttgataata aaaaaagatg agcttttgct catctcaaag gggttagatt
     3901 attcttactt tggggaaagt agaataaagg taaaagttaa ctgatgtcaa ctttgtcttt
     3961 tttgcatatc actactgagc ataaaaaaat cagaaaacca tagccttctg aaacaacttc
     4021 taacatacat tgtattttat acccaatatg taatttatga gttaatttta actcttataa
     4081 tgaaaattgt caataatata tcaaaaaaat attttttaaa tttatataat taaatgaatt
     4141 tatgtttata tataggtga
//
LOCUS       DAMKNB010000165         4115 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.171, whole genome shotgun sequence.
ACCESSION   DAMKNB010000165 DAMKNB010000000
VERSION     DAMKNB010000165.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4115)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4115)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4115
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.171"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            35..433
                     /locus_tag="PC494_003583"
     CDS             35..433
                     /locus_tag="PC494_003583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HDF3914034.1"
                     /translation="MIKKIEHVVITNNNIENYINFYKKFGFSSKEMSKNYKLNARNVK
                     INLNIKGYKFLPYVKNSKASRDNLCFKINTNIDEPKKYLEQNEIQIERGIVECTGVFG
                     NIKSIYLKKTNGNLIELSNHRITESKPWKI"
     gene            421..1359
                     /locus_tag="PC494_003584"
     CDS             421..1359
                     /locus_tag="PC494_003584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AEC family transporter"
                     /protein_id="HDF3914035.1"
                     /translation="MENLILSINVVLPLFLTMSLGYVLKKLGLFDTHTLNKMNNVCFK
                     SFLPLLLFFNIYNTDLDGSLNFKLMAVAVIIIFSIFLILVFIIPKIEKDNKTRGALIQ
                     GVFRSNFVIFGIPVTISLFGDKSIGVTSLLIAVIVPMFNVLSVVILEIFRGGKVNIKH
                     MIKSVLTNPLIIASFIGLTMLILNINIPTFLHKTIGDISKIATPLSLIILGGSFSFSA
                     IKGHINPIILGVCGKLILVPAIFLPISIFLGFRNVELASLMIMLSAPTAVSSFTMAQQ
                     MDSDSELAGQIVVFTSGFSIITVFLIIFILKQNNLI"
     gene            complement(1743..1967)
                     /gene="secG"
                     /locus_tag="PC494_003585"
     CDS             complement(1743..1967)
                     /gene="secG"
                     /locus_tag="PC494_003585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HDF3914036.1"
                     /translation="MSNILMGVQVVLGILLVISIMPQDSKNALPSEFGGEGSQAYFKP
                     KGKQAFLARVTKITAVLFFINALALLIVKK"
     gene            complement(2538..3830)
                     /gene="eno"
                     /locus_tag="PC494_003586"
     CDS             complement(2538..3830)
                     /gene="eno"
                     /locus_tag="PC494_003586"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HDF3914037.1"
                     /translation="MSVIELVYAREVLDSRGNPTVEVEVVLEDGAMGRAIVPSGASTG
                     AFEAVELRDGDKGRYLGKGVETAVANVNEIIAPEIEGMDAFDQPAIDAIMIELDGTPN
                     KGKLGANAILGVSMAVARAAADEIGLPLFQYLGGVNAKQLPVPMMNILNGGEHADNNV
                     DVQEFMILPVGACCFKEGLRMGAEVFHSLKKVLGEKGLACGVGDEGGFAPNLGSNREA
                     LELIVEAITKAGYKPGEDVMLGLDVAATEMYNKETKKYVLAGEGKELTAAEMVALYED
                     WSNNFPIITIEDGLDEEDWDGWKLLTEKLGNKLQLVGDDLFVTNTERLEKGIENGVAN
                     SILVKVNQIGTITETLDAIEMAKRAGYTAVISHRSGETEDSTIADLAVAVNAGQIKTG
                     APSRTDRVAKYNQLLRIEEMVGEQARYCGLKSFYNLKK"
BASE COUNT         1429 a          660 c          454 g         1572 t
ORIGIN      
        1 tttaataact tatataaaat cttaaggagt tgccatgata aaaaaaatag aacatgtggt
       61 cattactaat aataatatag aaaattatat caatttttat aaaaaatttg gtttttcatc
      121 taaagaaatg agcaaaaatt ataaacttaa tgctagaaat gttaagataa atcttaacat
      181 aaaaggttat aaatttttac cttatgttaa aaattcaaaa gcaagtagag ataacttatg
      241 ttttaaaata aacacaaata ttgatgagcc aaaaaaatac ttagaacaaa atgagattca
      301 aattgagcga ggaattgtag aatgtacagg tgtctttggt aatataaaat ctatttattt
      361 gaaaaaaact aatggaaatt taattgaatt atcaaatcat agaatcacgg agagtaaacc
      421 ttggaaaatt taatcctatc aataaatgtt gttcttcctt tgtttctcac aatgtcactt
      481 ggatatgttc taaaaaaatt aggtctattt gatactcata ctttaaataa aatgaataat
      541 gtctgcttca agtctttctt gccattatta ttatttttta atatatacaa tacagattta
      601 gatggttctc ttaattttaa gcttatggct gtagctgtta taattatttt ttcaatcttc
      661 ttaatcttag tctttattat tcctaaaatt gaaaaagata ataagacaag gggtgcatta
      721 atacaaggtg tatttcgtag caatttcgtt atatttggta ttcctgtgac aatttcacta
      781 tttggcgata agagtattgg agtcacatct ttattaattg cagttattgt acctatgttt
      841 aatgtattat ctgttgtaat tcttgaaatt tttagaggtg gcaaagtaaa tataaaacat
      901 atgattaaaa gcgtcttaac aaatccactc ataatcgcct cttttatagg attgacaatg
      961 ctaattttaa atattaatat acctacattt ttacacaaaa ctattggtga tatttctaaa
     1021 atagctactc ctttatcact tataattcta ggcggctctt ttagtttttc tgctataaag
     1081 gggcatataa accccattat attgggcgta tgtggaaaac ttatacttgt acctgctata
     1141 tttttaccaa ttagcatttt tcttggattt agaaatgtag aattagcttc acttatgata
     1201 atgttatctg ctccaactgc agtttcttca tttacaatgg cacaacagat ggattctgac
     1261 agtgaattag ctggacaaat tgtagtattt acttctggat tttctataat tacagtattt
     1321 ttaataatat ttattttaaa gcagaataat cttatttaat gatatttgat aacacaaatt
     1381 ggtattatga gaaacatata taaaattgat ttaactgcgt aaaaacatat tattatacta
     1441 tttttactat ataatataac tttgtgtata ttatctcatt aaacatggtg aaaatagtgt
     1501 tgctatatat tttttaattt gaaaaaaata tataaataca aacaatatat aaatataaat
     1561 aataaacgcc aacaaatagt caatctataa aataaaaact ggactaatca tataaaatca
     1621 ttagtccagc ttttatttta cgtacttttt atgttgatgt acttttatta aaaactaaat
     1681 ttaattttta aatgtctagc aaatgcacta attaaataat ggccagttat tcaacaatat
     1741 cactacttct taactataag taatgccaat gcatttataa aaaataatac tgctgttatc
     1801 tttgtaactc tagcaagaaa tgcttgtttt ccttttggtt taaagtaagc ttggcttcct
     1861 tctccaccaa attctgaagg taaagcattc ttagaatctt gaggcattat gctaattact
     1921 agtaaaatcc ctagtactac ttgcacaccc attaaaatgt tgctcattct tgcccctcct
     1981 atctgtttat tacttaaatt tcattactct ttagtgtatc acaataatat agccatttca
     2041 agactattat gctataaata acatacaaaa aaatatattg ttactataat atattactat
     2101 attctcaata taaaaatgaa taaaacttag aagagaaaac tatttaaatt aatacataaa
     2161 ttaacactta aaataatcta ctctcattgt atatattata aatagccacc aaaataaaac
     2221 aatcatttta aaatattgat ataactttta atttcaacat aatttaaaat aaataatcca
     2281 catttagcaa taatacttca atgacaatta tgattaaatc aaaatatgtc ttcactttta
     2341 ttttttaata aaaacctcct atgcaattag ataaaaatga gatagaaaca tttattcata
     2401 ttttttctga atctatgaat aaaattaagt aataaaatat aaaaaaggat aagtgaattg
     2461 aaaaatcaat taacacttat ctcttttata tcttatattc tctcttcatt aatctttttt
     2521 agtaaccatt ttaataacta tttttttaag ttatagaaag attttaatcc acaatatcta
     2581 gcttgctctc caaccatttc ttctattctt aataattggt tgtacttagc aactctatca
     2641 gttcttgatg gagcaccagt ttttatttga ccagcattta ctgcaacagc taaatctgct
     2701 atagtagaat cttcagtttc tcctgatctg tgagatataa cagcagtata tcctgctctc
     2761 ttagccattt ctatagcatc taaagtttca gttattgtac ctatttgatt aactttaact
     2821 aatatagagt tagctactcc attttcaatt cctttttcta atctctctgt gttagtaaca
     2881 aataagtcgt caccaactaa ttgtaattta ttacctaatt tttcagttaa taatttccat
     2941 ccatcccaat cttcttcgtc taaaccatct tctatagtta ttattgggaa gttgtttgac
     3001 caatcttcat ataaagcaac catttcagca gcagttaact cttttccttc tcctgctaaa
     3061 acgtattttt tagtttcttt gttgtacatt tctgtagcag caacgtcaag acctaacata
     3121 acatcttcac ctggcttata tccagctttt gttatagctt caactattaa ttctaaagct
     3181 tctctgtttg aacctaagtt tggagcaaat ccaccttcgt cacctacacc acaagctaat
     3241 cctttttctc ctaaaacttt ctttaatgaa tggaatactt ctgctcccat tcttaaacct
     3301 tctttgaaac aacaagctcc tactggtaat atcataaatt cttgaacatc aacgttgtta
     3361 tcagcatgct ctccaccgtt taatatgttc atcattggaa caggtaattg tttagcattt
     3421 actccaccta agtattggaa taatggtaaa cctatttcat cagcagctgc tctagctact
     3481 gccattgaaa cacctaatat agcattcgct cctaatttac ctttgtttgg agttccatct
     3541 aattctatca tgattgcatc tatagctggt tggtcaaatg catccattcc ttctatttca
     3601 ggtgctatta tttcatttac gttagcaaca gctgtttcta caccttttcc taagtatctt
     3661 cccttatctc catctcttaa ttcaacagct tcaaaagctc ctgtagatgc tcctgatgga
     3721 actattgctc ttcccattgc tccatcttct aatactactt caacttctac agttggattt
     3781 cctcttgagt ctaatacttc tctagcatat actaattcaa taactgacat ttgtatatct
     3841 cccttcgatt ttctattagt taaattttca tttactgtaa acatccgtct actattttaa
     3901 tctactttct atattatagt acataaagtt gcttttgaaa attaggtaca aatttatttg
     3961 atgggtaaat ttgtaaaagt tcctattttt attttatttt ttataatatt ttaatttata
     4021 taatataaaa aaacttgtct aaaatccaaa accaatctta aatacacaaa tattataact
     4081 agatttaaaa cattaaacat aaaatgtaca actaa
//
LOCUS       DAMKNB010000166         4059 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.172, whole genome shotgun sequence.
ACCESSION   DAMKNB010000166 DAMKNB010000000
VERSION     DAMKNB010000166.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4059)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4059)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4059
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.172"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            complement(576..1895)
                     /locus_tag="PC494_003587"
     CDS             complement(576..1895)
                     /locus_tag="PC494_003587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HDF3914038.1"
                     /translation="MLNINVFWIFLPIFSTTIEWIVLKFLLNEFSELRKNRLTLNSSI
                     VIAIMIITMLNTIEFNINIKLFICIFITYVLYKINYVVDKWKSVFISLLYWMLLIGFD
                     SIGLSIVMTLNSIKNMNDLLEDNLLKLELIMISKSLLIVLIPLLKFIRLKTKINKRDC
                     IYLSIPLIANIIGVIVIFEFIFKDKIIDSKESLIILTISTVFLLSNLSLVSIIGRIIK
                     DNSLKIEYEITKKRMNMQYKYYLNLQEYQLKIRKLYHDMNNHIICIQNVYGKNEFADK
                     YIKDINKQIKECNTIFNTQNMILDVILSDKKSICDMNNIYFLVDINFLECNFIEMPDI
                     CSIFSNIIDNAIEACIKIKDTSIQKKIKLRGTVINRLFVIKCENTKINEVVLKNNKVI
                     TSKKDSFLHGIGISSVKSSVEKYNGNVEIYSDKNKFTITIYIPLTRN"
     gene            complement(1889..2017)
                     /locus_tag="PC494_003588"
     CDS             complement(1889..2017)
                     /locus_tag="PC494_003588"
                     /inference="COORDINATES: protein motif:HMM:NF016296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3914039.1"
                     /translation="MEYIQFICKNTVVINGKDIPVSKYRMANLKKKLTYVLGDVLC"
     gene            complement(2156..2866)
                     /locus_tag="PC494_003589"
     CDS             complement(2156..2866)
                     /locus_tag="PC494_003589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018590547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF3914040.1"
                     /translation="MYRIVICEDDITQIAFLRECILKSLEGISSQIELFEFNSGEELL
                     ETNLEGIDIFFLDIKMLQLTGMDVAKIIRETNDTSEIIFITSIVDYIQEGYKVRAYRY
                     LLKPIDFGDLNESILSCISDIIKKRENFMLIENKGIINKILINSIMYIEVRKKVLTIH
                     TKNDTYYTKNSMDKIELELEKYNFFRCHKSYLINLEYIQFICKNTVVINDEDVPVSKY
                     RMADLKKKLTYVLGDVLC"
BASE COUNT         1531 a          571 c          293 g         1664 t
ORIGIN      
        1 gacaatttaa tatattttct aaatttctta ttataaataa ttactagttg attttttcta
       61 taaataatta aatcttctac attaaaaatc atttcttcag aatctatcac aactaagtcc
      121 tcctcaaatt agtaaaatat ttttctttaa tatttattac taatatcaac tttactatct
      181 aattagttat ttaattgttg tttttatgtt cctagttata aagtttatca aatttacatt
      241 ttattttttt atactatata gaacttttgg tcaataatgt taccatacta aggtcgcatt
      301 tgcagataaa aataactcta tttttctaaa tttatttaag atatatcatg caaataatat
      361 aactataaaa cctatcaaca ttttaaattc aaacaaatat aaatcacatt ttttgttcta
      421 ttattttatt gagtactaaa aaggatgtta tcttattagc atagcattca accattttta
      481 tcacctccaa atatcctatg ccttaaagat agcatcttct attttatctt tcaatactac
      541 tgctccaact gggcaattta gagccccaac tagaattagt tcctagttaa tggtatataa
      601 atagtaattg taaacttgtt tttatctgag tatatttcca catttccatt atatttttct
      661 actgaacttt ttacactact tattcctatt ccatgtaaaa aggaatcttt cttacttgta
      721 ataaccttat tattttttaa tacaacttca tttatctttg tattttcaca ttttattaca
      781 aataacctat ttataacagt tcctcttaat ttaatctttt tttgtatact tgtgtcctta
      841 atcttaatac aagcttctat tgcattatct attatatttg aaaatatact acatatatct
      901 ggcatctcta taaaattaca ttctaaaaaa ttaatatcta ctagaaaata tatattattc
      961 atatcacaaa tagatttttt atcacttaaa ataacatcta gaatcatatt ctgagtatta
     1021 aatatagtat tacattcttt tatttgctta tttatatctt taatatactt atctgcaaac
     1081 tcatttttcc cataaacatt ctgaatacaa atgatatgat tattcatatc atgatatagt
     1141 tttcttattt tcaactgata ttcctgtaaa tttaaataat atttatattg catattcatt
     1201 cttttttttg taatttcata ttctatcttt aaactattat cttttattat tcttcctatt
     1261 atgcttacta atgaaagatt tgatagtaaa aatacagttg atattgtaag tattattaaa
     1321 ctctctttag aatcgataat cttatcttta aaaataaatt caaatattac tattacacca
     1381 ataatgtttg ctattaatgg aatagataaa tatatacaat ccctcttgtt tatttttgtt
     1441 tttaatctga taaacttaag caatggtatt aatactatta gtaatgattt agatatcatt
     1501 attaactcta acttcaacaa attatcctct aataaatcat tcatattttt tatagaatta
     1561 agtgtcatta ctatacttaa tccaatacta tcaaatccaa ttaataacat ccaatatagc
     1621 aaacttataa atacactttt ccatttatcc actacataat ttattttata caatacatat
     1681 gtaataaata tacatataaa taatttaata tttatattaa actcaattgt attcaacata
     1741 gtaattatca taatagcaat tactatgcta ctatttaggg ttaatctatt ctttcttaac
     1801 tcactaaatt catttaataa aaattttaat acaatccatt ctatcgtcgt agaaaatata
     1861 ggtaaaaaaa tccaaaatac atttatattt aacataatac atctcccaat acatatgtta
     1921 attttttctt taaattagcc attctatatt tactaactgg tatatcttta ccattaataa
     1981 ctacagtatt tttacatata aattgaatat actccaaatt aattaaatag ctcttgtaac
     2041 atttttaaaa atttattctt tcttaaatca ctgaattcat ttgataaaaa ttttaataca
     2101 attcattcta tcgccgtaga aaatataggt aaaaaaatcc aaaatacatt tatatctaac
     2161 ataatacatc tcccaataca tatgttaatt ttttctttaa atcagccatt ctatatttac
     2221 taactggtac atcttcatca ttaataacca cagtattttt acatataaat tgaatatact
     2281 ccaaattaat taaatagctc ttatgacatc taaaaaaatt atatttttct agctctaatt
     2341 ctattttatc catactattt ttagtataat aagtatcatt tttagtatgt atagtcaaaa
     2401 cctttttcct aacctctata tacataatac tattaattaa aattttattg attatacctt
     2461 tattttctat cagcataaaa ttttctcttt tttttataat atccgatata caactcaaaa
     2521 tactttcatt taaatctcca aaatctatag gctttaataa atatctataa gcccttacct
     2581 tatagccttc ctgtatgtaa tcaactattg aagttataaa tattatttca gaagtatcat
     2641 tagtttctct aattatttta gccacatcca tgcctgttag ttgaagcatt ttaatatcta
     2701 aaaaaaatat atcaatacct tctaaatttg tttccaataa ttcttctcct gaattaaact
     2761 caaatagttc aatttgacta gaaataccct ctaaggactt taatatacac tctcttaaaa
     2821 aagctatttg tgtaatatca tcctcacaga taactattct atacataaac acccctcctt
     2881 agacattaga tctgaaaaca aataaaatat caatttataa ataattattt agttatacaa
     2941 ctaacatggt catcaaatac tattattcac ttaaaaaatc accccctatt tttagtatgt
     3001 taacaacaaa ataagaagat atcttagatt tttaaaaaca attaatactt aatgtagttt
     3061 tgtatactat ttataggtaa ttttttatat cattttaaac attaaaatta ttgatgttta
     3121 agaactatta tattgatagt aatatataat taatgatatc aaaaattttt aattagactt
     3181 ctctcttatt caagattttt ctatataaaa tctaagaata aatagaaaac taacatctaa
     3241 ccttttattt tttattttcg atctatttac ttgaatttta acataaatct atcttttagt
     3301 atatattaat catgctgaat ttgtgatgac atgtatacaa aatatcgttt agtattttct
     3361 aataaaaaat attactgaaa ttaaaaatct acaatagcat ttaacaagta aaaacatgtt
     3421 tacacaaata tataatttaa ggtctttaaa atagagtatg tattattcta aaaattagtt
     3481 atagttatca cataaaaata gaaaagaatt ttcaaaagat ttaaagaaca tacatacttc
     3541 aattgcagaa gatgtaatgt taagtgaact agcattcttc gaggaaaaat agactcaaaa
     3601 aattagaaaa tagaatcagg ttttagatga tttaagtatt tattttcaaa aaagaaattt
     3661 gattctaagt taataaagaa atatttaaaa aaatcaaaaa attttcttaa ataagtaata
     3721 ggttttgtaa aaatggaaaa atatcaaaat aagactatga tttttaaaac tatagcctta
     3781 tcaataaatt tttatttaaa gaacacacat aaatattttt aaacctaatt tatgtgaagt
     3841 tttatgtatt ttttatataa gtagtattct aatcttactc atctaatata ccaaaaagac
     3901 tgtaagtaag ttcactttta tgcaaactta cccacaatct cttttacaca ttaattctat
     3961 ttattaaaat taaaaatatt tactgctatt ctacccaata aagatgatac tgttgttgtt
     4021 ctggctggta ctgttacttc tatttctcct gtatctgct
//
LOCUS       DAMKNB010000167         3975 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.173, whole genome shotgun sequence.
ACCESSION   DAMKNB010000167 DAMKNB010000000
VERSION     DAMKNB010000167.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3975)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3975)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3975
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.173"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            24..653
                     /locus_tag="PC494_003590"
     CDS             24..653
                     /locus_tag="PC494_003590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2953 domain-containing protein"
                     /protein_id="HDF3914041.1"
                     /translation="MELNELFNFKYLIIAVIFIISVTMLILISHINILIIADIKNKDI
                     CLKLNIKYMFNLININRQLYPAENSKNNDKKEGMKNNIDSSILLADDLLSIYRLLKKI
                     KIHELYSNINFGTGNIGLTSSVYVLINTLYGNLFNMIDAEKMYLNVNPDFTKDYVLGN
                     IRIHIRPRIKALFNIIIMINKIMNKNKGNKEGDSNESNRFDTESYGNNS"
     gene            607..1035
                     /gene="ytfJ"
                     /locus_tag="PC494_003591"
     CDS             607..1035
                     /gene="ytfJ"
                     /locus_tag="PC494_003591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GerW family sporulation protein"
                     /protein_id="HDF3914042.1"
                     /translation="MRATGSIQSLMETTLETIKGSIDANTIIGDPIKTDTTVVVPISK
                     VTIGFGIGGGEYSKGYDDKDREIELKNEKSDTNFAGGSAGAISVQPVAFVVVESGETR
                     IMSLDSNINLVDNILSITPRVLEKIQNISQSNKNQDKNNM"
     gene            1283..1723
                     /locus_tag="PC494_003592"
     CDS             1283..1723
                     /locus_tag="PC494_003592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HDF3914043.1"
                     /translation="MSDKELSILLLESMNNFHNLIKIINNERYKKDKVLTERQFFALV
                     KIRKHDKIELKNLSRDLHVSTSSLCILLNKLVEQEYVYREEDSRDRRNTFYGITKNGE
                     KILDNEILKFVSIISDKMDCLDIDNKDKLFTSLEESKNIIEQLF"
     gene            1739..3190
                     /locus_tag="PC494_003593"
     CDS             1739..3190
                     /locus_tag="PC494_003593"
                     /EC_number="3.4.11.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucyl aminopeptidase"
                     /protein_id="HDF3914044.1"
                     /translation="MNIKYSKEILKSLENAITVVALFEGEDVFTTFDKINMISRNFNS
                     KENSIDTVTLIENNNLVNVCFVGFGKRELLNREKIRIIGGNLCKKLKNILKNEAYKSS
                     DVNVLNLNLNSDEIGCFVEGILLGNYKFDKYKTKSKDFERKEVDTITIFTEKEVECQI
                     EKAKILANSTIIARNLVNEPSNVIYPKTLAVETVKLGAEFGFNVDVYEEEKIKALGMD
                     AFFAVSRGSINKPRFIVMRYFGDKESTDILGLVGKGLTYDTGGYSLKSNASMLDMKTD
                     MAGAASVIGAMCAISQSKLKKNVIAVVAACENALSGGSYKPGDIISSMAKKTIEVLNT
                     DAEGRLTLADAIYYIINNEKVTKVVDVATLTGAALTLLGNVATPIVTNNDDFYCELEK
                     AATLSGERVWKMPIYDEFKDMIKGEEADLKNTGGKNAGCITAGAFIGEFVGNTPWIHM
                     DIAGTSTSSKSIGYKAKGATGEPVRTLYYLAEI"
     gene            complement(3281..3949)
                     /locus_tag="PC494_003594"
     CDS             complement(3281..3949)
                     /locus_tag="PC494_003594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YwaF family protein"
                     /protein_id="HDF3914045.1"
                     /translation="MFKIFLFSSEQFVSLFIFGLFLYYCPKLTKNILPYSYTVEKIIC
                     TLLVIIMALEQLLLISSGNYSTLNSLPIGINYICIYLCIAILIFKQYHLFNIFFSWSL
                     VCSVGELIFSKNLGYEFPSLIYFIFIFSKCLIIYADIYMVDVRKFRVNRYALRDNLAI
                     CFIYFSFIFLLNTFTNSRYYYGFLSHSTTAIFTFIFVTSIMYIPALLFNRDTFILEKK
                     KKSK"
BASE COUNT         1659 a          356 c          678 g         1282 t
ORIGIN      
        1 aattttttga tgataatata aacatggagc ttaatgaatt atttaatttt aagtatttaa
       61 taatagctgt aatttttatt ataagtgtaa ctatgttgat tttaatatct catataaaca
      121 tcttaataat agctgatata aaaaacaaag atatttgttt aaagcttaat ataaaataca
      181 tgtttaattt aataaatata aatagacaac tttatccagc tgaaaatagt aaaaataatg
      241 ataaaaaaga ggggatgaag aataatatag attcaagtat attattagct gatgaccttt
      301 tgagcattta tagattatta aaaaagataa aaatacatga actttattca aatattaatt
      361 ttggaactgg aaatattggc ttaacatctt ctgtatatgt attgataaat actttgtatg
      421 gaaatttatt taatatgatt gatgcagaaa aaatgtattt aaatgtaaat ccagatttta
      481 caaaagatta tgttttagga aatataagga tacatataag gccaagaata aaagctttat
      541 ttaatattat aataatgatt aataaaatta tgaataaaaa taaaggaaat aaggaaggtg
      601 atagtaatga gagcaacagg ttcgatacag agtcttatgg aaacaactct tgaaacaatt
      661 aaaggttcta tagatgcaaa tactattata ggagacccta taaaaacaga tactacagtg
      721 gttgtaccta tatcaaaggt tacaattggc tttggtatag gaggaggaga atactcaaaa
      781 ggatatgatg ataaagatag ggaaattgaa ttaaaaaatg aaaaatcaga tacgaatttt
      841 gctggaggta gcgcaggggc tatatctgta caaccagtag catttgtagt agttgaaagt
      901 ggagagacta gaataatgag tttagatagt aatatcaatc tagtggataa tatattatct
      961 ataactccta gagtattgga gaaaattcaa aatatatcac aaagtaataa gaatcaagat
     1021 aaaaacaata tgtaagaata aaatattttt aaatatgtat atagttttaa gtaaagtagt
     1081 ggggttaata taaatcccac tattttgttg tgtactttaa acatttatat ctaataagat
     1141 tttagtttaa aacaatttaa atagataata aagttgatat atagtataat tataaaaaga
     1201 aaagaagtat tatattatag atatataaac gcatttgaga tataagaggg agttataaat
     1261 cattagtttt gaggtgaatg ttatgagcga taaagaatta tctattttgt tgttagaaag
     1321 tatgaataat tttcataatt taataaagat tattaataac gaaagatata aaaaagataa
     1381 ggttcttaca gaaagacagt tctttgcctt agtaaaaata agaaaacatg ataaaataga
     1441 gcttaaaaat ctaagtagag atttgcatgt atctacttct agtctgtgta tactacttaa
     1501 taaattggtt gagcaagagt atgtatatag ggaagaagat agtagagata gacgaaatac
     1561 tttttatgga ataactaaaa atggagaaaa gatattggat aatgaaatac taaagtttgt
     1621 atctataata agtgataaaa tggattgcct agatatagat aataaagata aattatttac
     1681 ttctttggaa gagtctaaaa atataataga acaattattt taaaaaggag aatttattat
     1741 gaatataaag tattctaaag agatattaaa aagtttagaa aatgctataa cagtagtagc
     1801 tctatttgag ggagaagatg tttttacgac atttgataaa ataaatatga taagcagaaa
     1861 ttttaattct aaagaaaata gtatagatac tgtaacatta attgaaaata acaatttggt
     1921 aaatgtttgt tttgttggtt ttggtaagag agagttattg aatagagaaa aaattagaat
     1981 cataggtggg aatttgtgta aaaaattaaa aaatatattg aaaaatgaag catataagag
     2041 tagtgatgtt aatgtactga atcttaattt aaatagtgat gaaataggtt gttttgtaga
     2101 agggatatta cttggaaatt ataagtttga taagtataag acaaaaagta aggattttga
     2161 aagaaaagaa gttgatacta taactatatt tactgaaaaa gaagttgagt gtcaaataga
     2221 aaaggctaaa atattagcta attcaactat aatagctaga aatctagtta atgaaccatc
     2281 aaacgtaata tatccaaaaa cattagcagt agaaacagtt aaacttggtg cagagtttgg
     2341 gtttaatgtt gatgtttatg aagaagaaaa aataaaggca ttgggaatgg atgctttttt
     2401 cgctgtttca agaggttcaa ttaataaacc aagattcata gtaatgagat actttggaga
     2461 taaagaaagt acagatatat taggtctagt aggtaaagga ttgacttatg atactggtgg
     2521 atattcttta aaatcaaatg cttctatgct agatatgaag acagatatgg ctggtgctgc
     2581 gagtgttata ggtgctatgt gtgctatatc tcaaagtaaa ttaaagaaaa atgttatagc
     2641 agtagtggct gcatgtgaga atgctttatc aggaggttca tacaaacctg gagatataat
     2701 tagttctatg gcaaagaaaa ctattgaagt tttaaatacg gatgcagaag gtagacttac
     2761 attagctgat gcaatatact acattataaa caatgaaaaa gtaacaaagg tggttgatgt
     2821 agctacatta actggtgctg ctttaacatt gttaggtaat gttgcaactc ctatagtaac
     2881 aaataatgat gatttttatt gtgaattaga aaaagctgcc actttatcag gggaaagggt
     2941 atggaagatg ccaatttatg atgaatttaa agatatgata aaaggagaag aagcagacct
     3001 taaaaacact ggtggtaaaa atgctggatg tataacagca ggagctttta ttggtgaatt
     3061 tgttgggaat actccttgga tacatatgga tatagcgggg acaagtacat catcaaaatc
     3121 aattggatac aaagcaaagg gggctacagg agaacctgtt agaacattgt actatttggc
     3181 agaaatctaa aaaacaatta taaaatataa tttataaagc cacgtggata tttttgtaat
     3241 ttaagattat ctatgtggct ttatttttta tttaagtaaa ttatttactc tttttctttt
     3301 tttcaagtat aaaagtatct ctattaaata aaagagcagg tatgtacata atactagtaa
     3361 caaaaataaa cgtaaaaata gcagttgtgc tatgacttaa aaaaccataa tagtacctag
     3421 agttggtaaa tgtgtttagt aaaaatatga atgaaaaata aataaaacat atagctaagt
     3481 tatctctaag tgcatatctg ttaactctaa attttctaac atcaaccata tatatatctg
     3541 cataaattat caagcactta gagaagataa agataaaata tattaagcta ggaaattcat
     3601 agcccaagtt tttagaaaaa atgagttctc caactgaaca aactaaactc caagaaaaaa
     3661 atatattaaa aagatgatac tgcttaaaaa ttagtatggc tatacacaga tatatacaaa
     3721 tataattgat tccaattggt aaagagttta gagtactata attacctgaa gaaataagta
     3781 ataattgctc tagagccata attattacaa gtaatgtaca aattatcttc tcaactgtat
     3841 agctataagg taaaatattt ttggttagtt ttggacaata gtataaaaat aatccaaata
     3901 taaagagact tacaaattgt tcactagaaa aaagaaaaat tttaaacata taacattctc
     3961 tcctataata aattt
//
LOCUS       DAMKNB010000168         3811 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.174, whole genome shotgun sequence.
ACCESSION   DAMKNB010000168 DAMKNB010000000
VERSION     DAMKNB010000168.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3811)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3811)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3811
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.174"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            33..701
                     /locus_tag="PC494_003595"
     CDS             33..701
                     /locus_tag="PC494_003595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3914046.1"
                     /translation="MENITSYFTTILCVFICLSSVFIFTQLARVFINKKKINQKIKSR
                     NGFRYDRDFIEARREEIHIKDNNNNKNKSNNKKLKEEKVFKYDNGDLYKGEFVDGKKN
                     GFGIYIFSGKEKYEGLWKDDKMHGIGKYTYRDGSIYTGEFKYGLKNGLGKLTYPNNDI
                     YKGYFLDNKKNGKGVLYKNDGNKQAGIWEDDEQCKSLDFKDLNNNKINNVYQNRLNNN
                     KLKV"
     gene            860..1366
                     /locus_tag="PC494_003596"
     CDS             860..1366
                     /locus_tag="PC494_003596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HDF3914047.1"
                     /translation="MKEYVVVDLETTGLDPYKGCEIIEIGITEIKNEQIVKNYSRLIK
                     PKGIISSFITELTHISNEMVENEEPLELVLPRFRKYIGDRTIIAHNAKFDLKFLNYYL
                     RMLDLEPINNYICTVELLKKCKSYKGKNKKLETACAYYNIENINAHRADSDTLATAKL
                     FLKIKDEY"
     gene            1494..2510
                     /locus_tag="PC494_003597"
     CDS             1494..2510
                     /locus_tag="PC494_003597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglycosylase domain-containing protein"
                     /protein_id="HDF3914048.1"
                     /translation="MGYYNDNDNNKIRRKKISNNKDSNKKSKHSYTSANKKNKSPNTS
                     SSKRMSEKVDSQNLIKRDRDSFTRDNVRPLNTDYNQRERRRVEYKQREKKLKSKKRKK
                     QKRIRIVRALLSIMLVALIIFSVAGAIFTVSAIKGSPEVTKKLIRSKYISSEVVSIKQ
                     MPNDLKHAIVSIEDERFYKHKGVDVISLVRSVLNNVFTDTTQGASTIDMQVSKNLLTS
                     NDKTMKRKIRDMYNAKQMNKIMTKDEILEAYLNNMYLGKNAYGAAKGAEVYFGKKVSE
                     LNLAECAMLAGMTNNPARYIDHGEAKKRQVIVLYKMHQLGYITDKEYRIAKADDTPFK
                     SEID"
     gene            2864..3568
                     /locus_tag="PC494_003598"
     CDS             2864..3568
                     /locus_tag="PC494_003598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="B3/4 domain-containing protein"
                     /protein_id="HDF3914049.1"
                     /translation="MKKFVIEDAFWNLFPSAKIGVVICNDIDNSIKDEDYKKIILKGE
                     EEALKYLEDSEFSNNQVIKVWREAFKKFKTKKGARSSIEALLKRVHNGNNIGTINPLV
                     DIYNFISLKYALPCGGEDIDKFIGDIRLTRAIGNEEFIPLGTDENSFPYEGEIIYKDD
                     GGAICRCWNWREAVRTMLTEDTNNAFLCIELVDESRFKEFENALNELAKIVQEKLGGN
                     CKISILDIDNKEVSVD"
BASE COUNT         1634 a          325 c          657 g         1195 t
ORIGIN      
        1 ttttaaataa attttttaaa gggtgatttt ttatggaaaa tataactagt tattttacaa
       61 caatactatg tgtatttata tgcttatcat ctgtatttat atttactcaa ctagctagag
      121 tatttattaa taagaagaag attaatcaaa aaattaaatc aagaaacgga tttaggtatg
      181 atagagattt tattgaagcc agaagagaag aaatacatat aaaggataac aataataata
      241 aaaataagag taacaataag aaattaaagg aagaaaaagt atttaaatac gataatggtg
      301 atttatataa aggtgagttt gttgatggaa agaaaaatgg atttggaata tatatttttt
      361 caggtaagga aaagtatgaa ggattatgga aagatgacaa gatgcatgga ataggaaaat
      421 atacttatag agatggttca atatatacag gtgaatttaa atacggatta aaaaatggtt
      481 tgggaaaatt aacatatccc aataatgaca tttataaggg atatttttta gataataaga
      541 aaaatggtaa gggtgtatta tataaaaatg atggaaataa acaagcagga atatgggaag
      601 atgatgaaca atgtaaaagt ttagatttta aagatttaaa taataataaa ataaataatg
      661 tttatcaaaa tagattaaat aacaataaat taaaagttta attattctaa taaaaaaatc
      721 tttatttatg atggaatata ggatatatct atgttgtaat ttgtaaaatc ttcctatatc
      781 atataaaatt aagtattgat tagtctatta cataaatata gaatataaat atatccattt
      841 aataataagg agaagagata tgaaagagta tgtagttgtg gatttagaaa ctacaggatt
      901 agatccatat aaaggttgtg aaataataga aataggaata acagaaataa aaaatgaaca
      961 aattgtaaaa aactattcaa ggttgataaa acctaagggg ataatttctt catttataac
     1021 agaattgaca catataagta atgaaatggt agaaaatgaa gaaccactag aattagtttt
     1081 acctagattt agaaaataca taggtgatag aactataatt gcacacaatg cgaaatttga
     1141 tttaaaattt ttaaattact atcttagaat gttagattta gaaccaataa acaattatat
     1201 atgtacagta gagttattaa aaaaatgtaa aagttataaa ggaaaaaaca agaaacttga
     1261 aacagcttgt gcttattaca acatagagaa tataaatgct catagagctg acagtgatac
     1321 attagcaact gcaaaactat ttttgaaaat aaaagatgaa tattaattat aaatatagag
     1381 aaaattagtg aaaatatcct ttataaaatt gacccttaag cttacaattt tgttctttga
     1441 tttattttgt agaacaatgt ataatgtacc ttatatgaag aagggagact aaaatgggtt
     1501 attacaatga taatgataat aataaaataa gacgtaaaaa aattagtaac aacaaagata
     1561 gtaataaaaa atctaaacat tcttatactt cggcaaataa aaaaaataaa agtcctaata
     1621 caagttccag taaaagaatg agtgaaaaag tagattcaca gaatcttata aaaagagata
     1681 gagatagttt tacaagagat aatgtaagac ctttaaatac agattacaat caaagagaaa
     1741 gaagaagagt cgagtataaa caaagagaga aaaaattaaa aagtaaaaaa agaaaaaaac
     1801 aaaaaaggat tagaatagtt agggcattat tatctattat gttagttgca ctaattatat
     1861 tttcagtggc aggtgcaata tttacagttt cagctataaa agggtcacca gaagttacta
     1921 aaaagttaat taggtctaaa tatataagta gtgaggttgt aagtataaaa caaatgccaa
     1981 atgatttaaa acatgcaata gtttccatag aagatgagag attttataag cataaaggag
     2041 tagatgttat ttctctagtt aggtcagtat taaacaatgt gtttacagat acaacacaag
     2101 gtgcaagtac tatagatatg caagtttcaa aaaacctgct tactagtaat gataaaacta
     2161 tgaagcggaa aataagggat atgtataatg ctaagcagat gaataagatt atgactaagg
     2221 atgaaattct tgaagcatat ttaaataata tgtatctagg taaaaatgca tatggagctg
     2281 caaagggagc tgaagtctac tttggtaaaa aagttagtga attaaattta gctgagtgtg
     2341 ctatgttagc tggtatgaca aataatcctg caaggtatat tgaccatgga gaggctaaga
     2401 agagacaagt gattgtactg tataagatgc atcagcttgg ttatataact gataaggagt
     2461 atagaatagc aaaagctgat gacactccat ttaaatcaga aattgattaa aattgtaaga
     2521 atatagtatt ttcaatagtt taaacaaaca aaaatgtaat aaaaaaggtg atttgccacc
     2581 catttgccac cataattata atctaatggc aaattgtttt aatgtacaaa ctagataata
     2641 gaatattgtc ttaaatgcta tattatgcta aaatttaatt gtattttgta aattaaaaaa
     2701 cttataattt agttttctag ggttccgcat tttataatgg tcaggtccaa gagaaaacgc
     2761 gcaattgttg tgtacacgga aggataaaag cctgggagat atttaagaat atttctatag
     2821 gcttttttat ttttacatat tttaaatttg aggaggtttt ctaatgaaaa aatttgttat
     2881 tgaggatgca ttttggaatc tatttcctag tgcaaaaatt ggagttgtta tttgtaatga
     2941 tatagataac tctataaaag atgaagacta taagaaaata attttgaagg gagaagaaga
     3001 agcattaaaa tacttggagg actcagaatt tagcaacaac caagtgatta aagtatggag
     3061 agaagcattt aaaaaattta aaacgaaaaa aggagcaagg tcttctattg aagcattatt
     3121 aaaaagagtt cataatggaa ataatatagg aactattaac cctttagtgg atatctacaa
     3181 ttttatctca ttaaaatatg cattaccttg tggaggggag gatatagata aatttatagg
     3241 agatattagg ctaactagag caattggtaa tgaggagttt atcccactag ggacagatga
     3301 aaattcattt ccatatgaag gagaaataat ttataaagat gatggtggag caatttgtag
     3361 atgttggaat tggcgtgaag cagtgagaac aatgcttact gaagatacta acaatgcctt
     3421 tttatgcatt gaattagtag atgaaagtag atttaaagaa tttgaaaatg ctttaaatga
     3481 attagctaaa atagttcaag aaaaattggg tgggaattgt aaaatttcaa ttttagatat
     3541 tgataataaa gaggtatcag tggattaata tggaggtgct gttgtaatgg actattctag
     3601 ttataaagat acttatattt agggtaagaa ggtctatttt agatataacg attatcaaag
     3661 gatataatat agaaaataaa aatgtagaat ataaaaagcc tttaaaataa gaaaaaaatg
     3721 tattttaaag gcttttatta tactcttttt tatttgcata attaacaata aaaatatatt
     3781 gttaattata atatttttat ttaaaaacga t
//
LOCUS       DAMKNB010000169         3666 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.175, whole genome shotgun sequence.
ACCESSION   DAMKNB010000169 DAMKNB010000000
VERSION     DAMKNB010000169.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3666)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3666)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3666
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.175"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            268..1644
                     /locus_tag="PC494_003599"
     CDS             268..1644
                     /locus_tag="PC494_003599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk family potassium uptake protein"
                     /protein_id="HDF3914050.1"
                     /translation="MKTIVRRLILYADGMRPTQIMVSGFAAIIVIGALLLTLPIASQS
                     GESIGLLNALFTATSAVCVTGLVMVDTATYWSLFGQIVIITLIQIGGLGFMTVATMFS
                     LMARKKIQLRERLLIQESLNQADLSGLVRLTRFVLIITITIEGIGALVLSTVFIPQFG
                     LSKGIWYSVFHAISAFCNAGFDLMGSVSGPFTSLNSYVNNFTVSMTVCALIVLGGLGF
                     PVVLDIVRKRRFSKLNVHSKVVLFSTATLIFVGALFIFLIEFNQKATMADLPLKGKVL
                     SAIFQSVTARTAGFNTLDLATLRESSVFVMIILMFIGASPASTGGGIKTTTLAVLIIT
                     VRSFLSGKSDIEAFERRLAPSTIKKSLGIFVISISAVIFGTLIISITQPNFTLVQSAF
                     EVTSALATVGSSLAGTPNLNALGKIIIIIFMFMGRVGSLTLFMAILSGGRRKSQPIRY
                     AEGKIMVG"
     gene            1931..2602
                     /locus_tag="PC494_003600"
     CDS             1931..2602
                     /locus_tag="PC494_003600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HDF3914051.1"
                     /translation="MKQYIVIGCGRFGSSVASTMHLLGHQVMAIDKNEDSVQSISDKV
                     THSLIVDVTDEQALRSLGLGNFDVAVVAIGSDIRASIMATLIAKEMGVELIICKAKDE
                     LQAKVLYKIGADRVVFPERDMGVRVAHNLVSDNILDHIELDPEYSIVEIVTPNSWVGK
                     TLIELELRARYEITVLAIKTGKNINVTPSPDEELTAGSILVIIGQNTSITAITSGNKG
                     IIRRR"
     gene            2791..3588
                     /locus_tag="PC494_003601"
     CDS             2791..3588
                     /locus_tag="PC494_003601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HDF3914052.1"
                     /translation="MITNINSKDNEKLKYTRALLKSKNRNKESKFIIEGYRIVMLALE
                     CMANLDYVFINEEFENKKEHVKLLEDLDKKNTKIYKTTNKNFKELVDTENTQGIIGVV
                     SFKKKKLSESINKKDKFVLILDRIQDPGNMGTIIRTADSAGVDAIIALKGCVDIYNPK
                     VIRSTMGSIFDMNIIDASQDETVDMLKSLDFNIVSSYLNTENFYDKIDYGSKVALVIG
                     NEANGINEELVSKSDILVKIPIYGKAESLNAAISSAILMYEIKKYLI"
BASE COUNT         1394 a          407 c          675 g         1190 t
ORIGIN      
        1 aaataaattt taagtacaaa atagtaaaag ctatgatagt tttagaccta ttatatgtaa
       61 aaaatataga tgtttttggt gcaatttaaa ttaaaagata tatataaaaa tttaaaatat
      121 tccaaacaga aattataaaa attactatca ttgtctttat acaatattta tactataata
      181 gaataataat ttagaggaaa gctctaaaaa taaacaaatt aagggtctta acagtagtga
      241 ttttatgtta aggaggtata aagaaagttg aaaacaatag ttagaagact tattctctac
      301 gcagatggaa tgcgtcctac tcaaataatg gtatctgggt ttgctgcaat tattgtaatc
      361 ggagcattgt tgttaacact cccgatagcg tcgcagagtg gagagagtat aggcttatta
      421 aatgctctat ttacggctac ttcagcggtt tgtgttactg gtctagttat ggtagataca
      481 gcaacttatt ggagtttatt tggacagata gttataataa cattgataca aattggtggt
      541 cttggattta tgaccgtagc cacaatgttt tcacttatgg cacgaaaaaa aatacaacta
      601 agagaaagat tattaataca agagtcatta aatcaagctg atttatcggg acttgtaaga
      661 cttacaagat ttgtattaat aataaccata acaatagagg gaataggtgc actggtttta
      721 tcaactgtct ttattccaca atttggtttg tctaaaggga tatggtatag tgtatttcac
      781 gcaatatcag cgttttgtaa tgccggattt gacttgatgg gcagtgtaag tggcccattt
      841 acatcgttaa attcttatgt aaacaacttt acagtatcaa tgactgtttg cgcacttata
      901 gtgcttggag ggctaggatt ccctgttgta cttgatattg taagaaaaag aagattttca
      961 aaattaaatg tgcattctaa ggttgtattg ttttcaactg ctacacttat ttttgtgggt
     1021 gcattattta tttttcttat agaatttaat caaaaagcta ctatggcgga cttgccttta
     1081 aagggaaaag tactatcagc aatatttcaa tcagtaacag caagaactgc tggttttaat
     1141 acacttgatt tagctacttt acgagaaagt agtgtatttg taatgataat tttgatgttt
     1201 attggagcat cacctgcatc aactggtggg ggtataaaaa caacaacact agctgtttta
     1261 atcattacag ttagaagttt tctatcagga aaatcagata tagaagcttt tgaaagaaga
     1321 ttagctccat caactataaa aaaatctctt ggtatatttg taattagtat atcagcagtt
     1381 atttttggaa cattgattat ttcaataact cagcctaatt ttacattagt tcaatcagct
     1441 tttgaggtta catcagcact tgctacagtt ggttcaagtt tagctggaac tccaaactta
     1501 aatgctttag gtaagattat aataataatt tttatgttta tgggtagagt tggttctctt
     1561 actttattta tggctatact ttctggtggt agaagaaaga gtcaaccaat cagatatgca
     1621 gaaggtaaaa ttatggttgg ttaagttacc aaggagtagt ataaatttat aatggattta
     1681 gagtagcact gtaaatctgt tgataaaata aatgagccta gatgtaatta tatgaagaaa
     1741 taaaatcaac taacgaacaa aattaattaa tgaaataaaa aaacagggaa ataaaataca
     1801 aataaaaagg taaatcaaaa ttaaattaat ctgtgtatat aaaattatat attgtgtata
     1861 agttttgtat gtgtaaacaa ttaatttaag agatattata taaattgtgt attagggagg
     1921 aagtttcgag atgaagcaat atatagtcat tgggtgtggg agatttggaa gttcagttgc
     1981 gtctactatg catcttttag gacatcaagt aatggcaata gacaaaaatg aagattcagt
     2041 tcaaagtata tctgacaagg taacccattc acttatagtg gatgttactg atgagcaagc
     2101 gttaaggtca ttaggtttag gtaactttga tgtagcagta gttgcaatag gttctgatat
     2161 aagggcatct ataatggcga ctcttatagc caaagaaatg ggtgtagagt tgataatatg
     2221 taaggcaaag gatgaattac aagctaaagt tctttataaa attggtgcag atagagttgt
     2281 atttccagaa agagatatgg gagtaagagt tgcacacaat ttagtttcgg ataatatatt
     2341 agaccatatt gaacttgacc cagagtattc aattgttgaa atcgtaactc caaatagttg
     2401 ggttggcaag acacttatag agcttgaatt aagagctaga tatgagataa ctgtacttgc
     2461 tataaaaaca ggtaaaaata taaatgttac accttctcca gatgaggaac ttacagccgg
     2521 aagtatccta gttataatcg gtcaaaatac tagtataaca gcgataacat ctggaaataa
     2581 ggggataatt agaagaagat aatttactat ttaatatata tttaattgca atgaaagtag
     2641 atagtatcat ataattatga atagttatat gatactattt ttttaatcga aggtagtatt
     2701 tatttgtaag attagataaa gagaagttaa attaaaagta aggaggctgt gctaatataa
     2761 aaatttataa gttattagca tttagataaa atgattacaa atataaacag taaggataat
     2821 gaaaagttaa agtatacaag agcactatta aaatcaaaga ataggaataa agagtcaaag
     2881 ttcataatag agggatacag aatagtaatg cttgcacttg aatgtatggc aaaccttgat
     2941 tatgtattta tcaatgaaga atttgaaaat aagaaagaac atgtaaaact attagaagat
     3001 ttggataaaa aaaacacaaa gatatacaag actactaata aaaactttaa agaattagtg
     3061 gatacagaaa atactcaagg aataataggt gtagtttcat ttaagaaaaa aaaattaagt
     3121 gaaagtataa ataaaaaaga taaatttgta ttgattttag acagaataca agacccagga
     3181 aatatgggga ctataataag gactgctgat tctgctggag tagatgccat aatagcacta
     3241 aagggatgtg tcgatatata caacccaaaa gtaattaggt ctactatggg ttctattttt
     3301 gatatgaata taattgatgc ttcacaagat gaaactgtgg acatgcttaa atcattggat
     3361 tttaatatag tttcaagtta cttaaataca gaaaattttt atgacaaaat agattatggc
     3421 tcaaaagtag cattggtgat aggaaacgaa gcaaatggaa taaatgaaga acttgtatca
     3481 aagtctgata ttttggttaa gatacctata tatggtaaag ccgagtcgtt aaatgctgcg
     3541 ataagctctg ctatactgat gtatgaaata aaaaaatact taatttaatg tattgtaata
     3601 aatataatgt catgttataa tcttgaatta aatagtagag tatcaaaaat agtcaatata
     3661 tattaa
//
LOCUS       DAMKNB010000170         3617 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.176, whole genome shotgun sequence.
ACCESSION   DAMKNB010000170 DAMKNB010000000
VERSION     DAMKNB010000170.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3617)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3617)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3617
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.176"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            complement(236..1252)
                     /locus_tag="PC494_003602"
     CDS             complement(236..1252)
                     /locus_tag="PC494_003602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HDF3914053.1"
                     /translation="MVTIKDIARNLGISYSTVSRCLNNNPNVSEKTKKKVVEEANRLG
                     FHFNVNARNLAKKETNRIGVIFSNNFNHQDTRKFFSDIMDSSINSIETNKYDFIIQPN
                     NNISGDSNVYKMVNGQMVDGLVIVSQSIKKEEYDFLKDNNFPHVFIYFKPSFIGEVDN
                     FFWDDNVYGGYIATKHLIDHGHKDIITVTSDDKSSKMHEDRTKGYLNAMEEANLKTEV
                     IKSKMDFESQVEFLEKYIDKIKKASAIFVQQDVPAISIIQELKTTYGINVPEDISIIG
                     YNNIELISYFRSHLSTIDDPREQVIKNGVDSLVNIINKKSTEHIPRKLYPRLIIRNSV
                     KRIK"
     gene            complement(1435..1797)
                     /gene="spoVAE"
                     /locus_tag="PC494_003603"
     CDS             complement(1435..1797)
                     /gene="spoVAE"
                     /locus_tag="PC494_003603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein AE"
                     /protein_id="HDF3914054.1"
                     /translation="MLMDYVRVFIVGGIICLIAQVMMDYFKMQTPYVMVTYVTTGVVL
                     TFLGLYEPLVKFAAAGATVPIIGFGYSLATGVIKSIQSDGFLGIFLGGTTATAGGIAA
                     AIFFGYIMSVVFTPKAKP"
     gene            complement(1811..2824)
                     /gene="spoVAD"
                     /locus_tag="PC494_003604"
     CDS             complement(1811..2824)
                     /gene="spoVAD"
                     /locus_tag="PC494_003604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein AD"
                     /protein_id="HDF3914055.1"
                     /translation="MKNKRIGKRTVKLENKPTIISTGTIVGPKEGEGPLKDYFDMIMT
                     DDLYGEKTWELAESKMVETASQQAIQKAGKKLSDVNYMLGGDLINQIVPASFAARELA
                     IPFLGIYGACSTMAEGLCIGSMLIDGGFADLVLSGTSSHYCTAERQFRFPLELGNQKP
                     MTAQWTVTGAGSVLLAPNGDGPKVKYVTVGKVIDEGIDDGNNMGPAMAPAAIDTIYSY
                     FEDTNDDPNSFDIIATGDLGTLGKQIAEDFLKEKGVDISKVYTDCGIEMFNLKEQDVH
                     CGGSGCGCSATVFAGYIYDKLRKKEFNKVMLVSTGALLSPTSTLQKQTIPCVAHAVVI
                     VNE"
     gene            complement(2978..3415)
                     /gene="spoVAC"
                     /locus_tag="PC494_003605"
     CDS             complement(2978..3415)
                     /gene="spoVAC"
                     /locus_tag="PC494_003605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein AC"
                     /protein_id="HDF3914056.1"
                     /translation="MDKNYKKYVDQISPKPTYLKNYTLAFIVGGIICMIGQAINDLYM
                     KVGGLDKLGASSATSITLIFIGAFLTGLGVYDLIGKRAGAGSIIPITGFANSIVSPAM
                     EYKREGYVLGVGANLFKIAGPVLVYGIGSSILCGIIYYIFKMF"
BASE COUNT         1174 a          644 c          386 g         1413 t
ORIGIN      
        1 ttatagattc atgatataaa atacaaataa tttattaatt tatattgtta aaataacgga
       61 ttttcaaata attgaataaa attattcatt catattataa aaactatctc aataaataaa
      121 ggagtacaat gtacttatat acacctactc cttttaattt ttatttatat tatttgttaa
      181 aaaacttcac ataatctata atatttttaa taaacgtttg atacttaaaa gcttactact
      241 ttattctttt aacgctattt cgtattatta accttggata taattttctc ggaatgtgtt
      301 ctgtactctt tttatttatt atatttacta aactatctac tccatttttt ataacttgct
      361 ctcttgggtc atctattgtt gataaatgcg acctaaaata tgatattaat tcaatattat
      421 tataccctat tatggaaata tcttctggta catttatacc ataagtagtt tttaactctt
      481 gtattataga aatcgctggt acatcttgtt gtacaaatat agctgaagct ttttttattt
      541 tatcaatgta tttttctaaa aattcaactt gagattcaaa atccatttta gatttaatga
      601 cttctgtctt taaatttgct tcttccatag cattcaaata tcccttggtt ctatcttcat
      661 gcatttttga actcttatca tctgaagtta ctgttattat atctttatga ccatggtcaa
      721 ttaaatgctt ggtagctata taacctccat acacgttatc gtcccaaaag aaattatcta
      781 cttctcctat aaaagatggt ttaaaatata taaatacatg tggaaaatta ttgtctttta
      841 aaaaatcata ctcttctttt tttattgatt gagacacaat tactaatccg tcaaccattt
      901 gtccatttac cattttatat acattactat caccactaat gttattatta ggctgtatta
      961 taaaatcgta tttattagtc tcaatagaat ttatagaact atccattata tcactaaaaa
     1021 actttctagt atcttgatga ttaaaattat ttgaaaagat tacccctatc ctgttagttt
     1081 ctttttttgc taaatttctt gcatttacat taaaatggaa ccctagtcta tttgcctctt
     1141 ctaccacttt cttttttgtt ttttcagata cattaggatt attgtttaag cacctagaaa
     1201 cagttgaata actgatacct agattccttg caatatcttt aatagttacc atctttatcc
     1261 cctacttcac ttcattttat tttgataata taatactaca ctatgttgta aataattgtc
     1321 aacttcaatt atgtaaacgc ttctttatat aaaaaatagg tggaatctaa aagatatcca
     1381 cctgctttat aaaaagttat tatttcaaaa acttattatt cttttaataa agatttatgg
     1441 ttttgctttt ggagtaaata ctactgacat aatatatcca aagaatatag ctgctgctat
     1501 tccaccagct gtagcagttg tacctcctaa aaaaatacct aaaaaaccat cactttgaat
     1561 tgattttatt actcctgtag caagtgaata tccaaatcct attataggaa ctgttgcacc
     1621 tgctgctgca aacttaacta atggctcata aagtcctaga aaagttaaaa ctacaccagt
     1681 tgttacatac gttaccataa catatggagt ttgcattttg aaataatcca tcattacttg
     1741 ggctattaaa catataattc cacctacaat aaatactctt acatagtcca ttaacatatt
     1801 atatcacttc ctactcattt actattacta ctgcatgtgc aacacatggt attgtctgct
     1861 tttgtagtgt acttgtcggt gaaagtagtg ctcctgttga tacaagcatt actttgttaa
     1921 attctttttt tctcaactta tcatatatat atcctgcaaa cactgtagct gaacacccac
     1981 atccacttcc accacagtgg acatcttgtt ctttaaggtt aaacatctct ataccacagt
     2041 cagtataaac ttttgatata tctacaccct tttcttttag aaagtcttct gctatctgtt
     2101 ttccaagagt acctaaatct ccagtagcaa ttatatcaaa gctatttggg tcatcattag
     2161 tatcttcaaa gtaagagtag atagtatcta ttgctgctgg agccatagct ggtcccatat
     2221 tattaccatc atcaataccc tcatctatta ctttaccaac agtaacatac tttacttttg
     2281 gaccgtctcc attaggagct aataatacac ttcctgctcc tgtaactgtc cactgagctg
     2341 tcattggttt ttgatttcca agttcaagtg ggaatctaaa ttgtctttct gctgtacaat
     2401 agtgacttga tgtacctgac agtactaaat cagcaaaacc accatctata agcatagaac
     2461 ctatacaaag accttctgcc attgtagaac aagctccata tatacctaaa aatggaatag
     2521 ccagttctct tgctgcaaat gatgctggaa ctatttgatt tattaaatcg ccacctagca
     2581 tataatttac atctgacaat tttttacctg ccttttggat agcttgttga gatgcagtct
     2641 ctaccatttt actttcagct aattcccaag tcttttcacc atataaatcg tcagtcataa
     2701 tcatatcaaa atagtccttt agtggtcctt caccttcctt aggacctact atagttccag
     2761 ttgatattat ggttggttta ttttctaact tgactgttct ttttccaatt cttttatttt
     2821 tcatattttc acaccttttt aattttgcat tttactattc aaatttttaa tattaattaa
     2881 atctgcacaa ttatttttca attagttact ttagtagcta ttttcagatt ttataccttc
     2941 ttcataatta ataaaattta aattaaataa aaatcatcta aaacatctta aaaatataat
     3001 aaataattcc acataaaata gaagaaccta taccataaac taaaactggt cctgcaattt
     3061 taaataagtt tgcacctaca cctaatacat agccttctct tttatactcc attgctggag
     3121 atactattga gttagcaaaa cctgttattg gaattataga accagctcca gctctttttc
     3181 ctattaggtc gtagactcct aatccagtta aaaatgcccc tataaatatt aatgttattg
     3241 atgttgcaga actagcacct agtttatcaa gacctccaac tttcatatac aaatcattta
     3301 ttgcttgccc tatcatacaa ataattccac ctacaataaa tgcaagtgta tagtttttta
     3361 aatatgtagg ttttgggctt atttggtcta catatttttt ataattttta tccatactaa
     3421 acacctctct aaagtattat ttgttaattt taaaaaaata aacctattat ttattttgac
     3481 tatctaaagt ttggtcaaaa aataaaaaag atgcctaata aagaaaaaat ctatttttcc
     3541 ataaagacac cttgttttta tatttttact tttttaatgc tttttattat tttaatatct
     3601 tttaataatt taaaaac
//
LOCUS       DAMKNB010000171         3483 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.177, whole genome shotgun sequence.
ACCESSION   DAMKNB010000171 DAMKNB010000000
VERSION     DAMKNB010000171.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3483)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3483)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3483
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.177"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            complement(214..597)
                     /locus_tag="PC494_003606"
                     /pseudo
     CDS             complement(214..597)
                     /locus_tag="PC494_003606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431032.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
     regulatory      838..935
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            990..1166
                     /locus_tag="PC494_003607"
     CDS             990..1166
                     /locus_tag="PC494_003607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3914057.1"
                     /translation="MFGNKMDKCTHVLTAYISSSYDYCNFLDTQLDDFILEYGESVVE
                     SCLHQVMVLVSKYN"
     gene            1392..1592
                     /locus_tag="PC494_003608"
     CDS             1392..1592
                     /locus_tag="PC494_003608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003723180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HDF3914058.1"
                     /translation="MNNGIVKWFNNEKGFGFISMEGRDDVFAHFSAIQTSGFKSLEEG
                     QQVSFDIVKGARGPQAENITIL"
     repeat_region   1957..2124
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=1957..1984
                     /rpt_unit_seq="tttacataccacatagttgatataaaac"
     gene            2342..2524
                     /locus_tag="PC494_003609"
     CDS             2342..2524
                     /locus_tag="PC494_003609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integrase"
                     /protein_id="HDF3914059.1"
                     /translation="MFKFYNNATLMFLSGTNIKTISERLGHADIKITMNSYSQFLEEM
                     DREAFENLSKILFIIF"
     gene            2595..3440
                     /locus_tag="PC494_003610"
     CDS             2595..3440
                     /locus_tag="PC494_003610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3914060.1"
                     /translation="MNIIKSITLLLTLLIVILMTGCSPRESASEVAKKYIDKMNSGDY
                     ETAYSLLSKDSKKKISIENLEEFQNILVSTKRIISYKIGKEKIIKKYKHDGKEYKNVV
                     KLEETFNIKNLLYKKDDSLKVNRYFVVENNKYKLLLYESFKKEFGINSMDLAQLKLND
                     FGLKYFKEVDLILKKAIAINPTDSKLYYAQACNYMNFDGFPGYSDTTYNALDSINKSL
                     KYLDKNDSDYKKNASNIYNLKGVILMFHKRFDEAQQYLNKSLYFNKDNEDPKYNLNTI
                     KKHLN"
BASE COUNT         1301 a          423 c          430 g         1329 t
ORIGIN      
        1 acagtaattt atctatagtg ttacttatat tttatatata tggctatttt tcaacatttt
       61 acaatatata taacatttat ttttttaact tttgtcagta aaatgtcagc aaaacacttt
      121 atccacaatt tttatataag ttttccacaa cttatcccca gtattatcca cataaaaaag
      181 gtagctctta tattattagc taccttttat ttattaatct tcatatttcc agctttttat
      241 ccaacttcct atttctatta ttttttcttc agttatttct tctccatcat gtaattttga
      301 aattaattct gataaaggat tgttatgtaa acctctaaaa actctttttt cctctatttt
      361 gatatattct ctctctttta ttaatactgt atagtgtaca tgcctcccaa ttctctatga
      421 tattaaaaaa ccttttttgg ttaatctagc taaaagtata attgtagttg tatgcttcca
      481 accatatgtt ttttctattt catctgcaac atcttttgat attacagttt tataaccagt
      541 attccatatg catttcataa tttttaattc tgtatctggt aattttttat ttagcataat
      601 atattccttc tttcaattta tgtcacttct tcttatgtca cttcttcaaa tttatctagc
      661 ttaaattata ataggagctt tttagaacaa aaactatatt taatttttac caggtactct
      721 acgtgtttat cctgttttta agtgtaaaat aatgttcata tctataaatt tatttaactt
      781 tcaaacaatc ctgttgaata ataactaatt ctattgtatt attttagttg tagaataaaa
      841 ctaaatcggc aaaactagag aaatttagtg acgcaaagct atagggacta agacttatat
      901 aaatatctta tgagttatgt cagccagttg ccaaagagat agtgttcttt ttgtttttat
      961 gaaagttttt tagggggata ataatttata tgtttggaaa taaaatggat aaatgtacac
     1021 atgtattgac tgcttatatt agcagttcgt atgattattg taatttttta gatacacaat
     1081 tagatgattt tatattagag tacggagaaa gtgtagtaga gtcttgttta caccaagtga
     1141 tggtattggt aagtaagtat aattagatag acattgattt ctagagaacc ctttttagtt
     1201 ttatctacat ttatattaat atatagcaat gtaaaacgtt taaatatatt tttaatatta
     1261 agaataacta aaatgttaac taaaaaatat aattaagtag acatttctat taatctatga
     1321 tacaatagta tttgtggtaa tacacaatta aatcaagtat atcttgatat aggttaatag
     1381 gagtattttt aatgaataat ggaatagtga aatggtttaa taatgaaaaa ggattcggtt
     1441 ttatatcaat ggaaggtaga gatgatgtgt ttgctcattt ctcagctata caaacttcag
     1501 gatttaaatc attagaagaa ggtcaacaag taagctttga tatagttaaa ggtgctagag
     1561 gtcctcaagc agaaaatata actatattat aatatataga tttttcggga aagactcttt
     1621 ttagagtctt tttttattgt taatatatgt aagataatca ttggtgaagt aaataaggta
     1681 tattgagtaa tgttcttgat agtttatatg ctaatgaatt tcaaaaaaat aagcactcct
     1741 ataaaaagag tgctcttaat gtaaatataa accttcattg gtccagccta ataccccgta
     1801 ttctccaagt tctaactctt ttttatatac attatcactt tcagccatat ctaacacaat
     1861 catttcttct ttagaatcaa tttgtaaaat atgaggactg tgtgttgtga caattatttg
     1921 tgtttttggg agaattgttt ttaatgtaat aaaaatttta cataccacat agttgatata
     1981 aaacgtaaat acaccatcta taaagggcag gtgttaaaac tctttacata ccacatagtt
     2041 gatataaaac ttaatatact taggtattcc tactggaaac ttttctcttt acataccaca
     2101 tagttgatat aaaaccccaa aataaactta gcatctccaa tgtttacaca tatacaatgc
     2161 tcttaaaatt gcagtgaacg cgcaatagtg caattgataa tacttattat atattctcaa
     2221 tgccttatat ttcaactgct aaacctcaat ttgtcacaaa tatcgctcac tgcaaaattt
     2281 ctatattttt attatatcat aacatataat taatattttc aattaatttt tacatttaat
     2341 tatgtttaaa ttctataata atgcaacttt aatgtttctt tctggaacta atataaaaac
     2401 tatttcagaa agattaggtc atgcagatat aaaaataact atgaatagct actctcagtt
     2461 tttagaagag atggacagag aagcatttga aaatttgagc aaaatactat ttattatatt
     2521 ttaaagaaga tgacttattc aatatttgat gctagaatat aattaataaa aatttaatta
     2581 taggtgattg tattatgaat attattaaaa gcataacttt actcttaaca ttattaattg
     2641 tgatattaat gacaggctgt tccccaagag aaagtgctag tgaagttgca aaaaaatata
     2701 ttgataagat gaactctggt gactatgaaa cagcatatag tttattaagt aaagatagta
     2761 aaaaaaaaat tagtatagaa aatcttgaag aatttcaaaa tattttagtt agtacaaaaa
     2821 gaataattag ttataaaata ggtaaagaaa aaatcataaa aaaatataaa catgatggaa
     2881 aagaatataa aaatgttgtt aaattagaag aaacttttaa tataaaaaac cttctttata
     2941 aaaaagatga ttctctaaaa gtaaatagat attttgtagt tgaaaataac aaatacaagc
     3001 tattattgta tgaaagtttc aaaaaagaat ttggtattaa tagtatggac cttgctcaac
     3061 ttaagcttaa tgattttgga ctaaaatact ttaaagaagt tgaccttata ctaaaaaaag
     3121 ctattgctat taatcctact gattcaaagc tttattatgc ccaagcatgt aattatatga
     3181 attttgatgg atttcctggt tattcagata caacatataa tgctttagat tcaattaata
     3241 aatctttaaa gtatttagat aaaaatgatt ctgactacaa aaaaaatgca agtaatatat
     3301 ataacttaaa aggagttatt cttatgtttc acaaaagatt tgatgaagca caacaatatt
     3361 taaataagtc cttatacttt aacaaagata atgaagaccc aaaatataat ctaaatacaa
     3421 taaaaaaaca tctaaactag atatttaatt tttgaattta taaaatattt ttttatgtat
     3481 aat
//
LOCUS       DAMKNB010000172         3462 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.178, whole genome shotgun sequence.
ACCESSION   DAMKNB010000172 DAMKNB010000000
VERSION     DAMKNB010000172.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3462)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3462)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3462
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.178"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            complement(122..1689)
                     /locus_tag="PC494_003611"
                     /pseudo
     CDS             complement(122..1689)
                     /locus_tag="PC494_003611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021426623.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="iota toxin protein Ib"
     gene            complement(1664..1807)
                     /locus_tag="PC494_003612"
     CDS             complement(1664..1807)
                     /locus_tag="PC494_003612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3914061.1"
                     /translation="MYVYYFESPEKFAFNKVIRTKNQNEISLEKFNEFKETIQDKLLP
                     YNR"
     gene            complement(2025..2207)
                     /locus_tag="PC494_003613"
     CDS             complement(2025..2207)
                     /locus_tag="PC494_003613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3914062.1"
                     /translation="MKKFRKHKSISNCISILLILYLTLGSLLPNNIYAQDLQSYSGKV
                     CNTTYKAPIERSEGFF"
     gene            complement(2596..3342)
                     /gene="cdtR"
                     /locus_tag="PC494_003614"
     CDS             complement(2596..3342)
                     /gene="cdtR"
                     /locus_tag="PC494_003614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LytTR family response regulator CdtR"
                     /protein_id="HDF3914063.1"
                     /translation="MDILIFDNDVCFGMKLKEKINNILIKEGFDNDVVRLYHNANLLL
                     KELTEKNKVRIYFIVVDAKYKISNELCDGLWIAQKIRESDYISPIIFLTNHIEMILGI
                     FDYRLEVMDFILKHDMEIAESKIKACIKIAHKRYIKEKNYRSNFFTIYSDFSLWKISF
                     DEVIYFETSTIPHKIKLVTTSRIFEFYKSLKSLPDLDACFIRVHKSFVVNKYHIVSLD
                     LKKNNIKMSNGHICRISNTYRNILKNIIKT"
BASE COUNT         1158 a          450 c          378 g         1476 t
ORIGIN      
        1 aaaaagaata tattagaaga agataatatt taaataaaaa ataccttata aagttaattt
       61 tttaatactt tataaggtaa atacatattg tattgtgggg ataaatttaa atcatttgat
      121 actaatcaac actaagaacc aataactctc tatcatcttg agtaattgta tatattctta
      181 atttcttgta tgtcataata ttttctccac ctgtaaaata actcctaaga ttaacacaat
      241 cagttttagg ttgatttgta tctcctaaat aattacgcaa ttctttatct ttagtttcaa
      301 tatctttaaa tccaaaatat tgtaaagtag cttcaactct atatttttgg acataatcga
      361 gagcttcttt attagtttat gttggtgtaa aatacatacc atttatataa gcctttattg
      421 tacttggatt aaatttaaaa tctgcagaat atattttatg tgtaactatt atttcttgaa
      481 cagttggaat tttaacttct ggttcatcaa gtatttcagg agtactattt agctctgtaa
      541 tagataagtt atctaagtat attgtatcac tatcaattaa tgctatattt atattagaag
      601 aatctttttc agtagtttca aattcataac taaattttgt atatccttgt tctagtacca
      661 aataatccgt tttttcttct tttactttta tatttacaat tattgaatta tatgttaaag
      721 gattttttga attttactaa aaacataacg tttataaggt tttagttcag acataggtat
      781 tttaatcttc gtctcaccat ttaatctatt tgctgagcct tttaaaccat cttgatttgt
      841 agtattaaca ttactccata tactagggta attattgtaa tcatcaaaat tagtaaagta
      901 agttggtgtt tttataagta tattcattcc tctttcaagt ttaacattac atatttgttt
      961 atcagacaaa gtttttaaac tgtctttaat cttattgcct atattatcat caaatatgag
     1021 ttcaacacaa ctttcatcta ttggtatatt attaaaatat aacaaaccat cttttttagt
     1081 agtgccaaaa gttttttcaa ttgcttctcc aattgtaagt tcaggtgttt tatcttctgg
     1141 gacctgtaaa cttttagcag taattcttct tttgtaagat tcattttctg tatctaatat
     1201 aatagataca gaaatactgt caatttgacc tatatcgtct taccaactat ttcattctgt
     1261 tactatttgt ccagaaccat tttttgtacc aaaatttcca cttacttgtg ttgtttctaa
     1321 tttaatttgc tttccatcat ctaatttttt taattaatta taatttatag gaatcagtct
     1381 agaactaaat tgatacattg tgttaagagc cataggtgaa aatccttttt tgagataagt
     1441 atttccagga gatagattat tgccaatttg attttcttgt gctttgatag ttgataatgc
     1501 atctccatct aacactaaat ttgttgttgg tgtcactttg tacataggtg cagtacctgt
     1561 gttgtagtat ctaatatttg catttatata tgcagattct cctttgttta tacttaatcc
     1621 agtatttcat gattatccat tgctattttg aacagcagtt gaattatctg ttgtatggta
     1681 ataatttgtc ttgtatagtt tctttaaact cattaaattt ttctaatgaa atttcgtttt
     1741 gattttttgt tcttattact ttattaaatg caaatttttc tggagattca aaataatata
     1801 catacatagg tttatctatt ttattttttg atatagcatt tcgaagttct ctatattctt
     1861 tttctcaaga atttgcttct atttgataat cataaaaata atttcttgtc tgagaatatt
     1921 tgcttatctc tatagaatct tttttatatg atcctaatac ttctttttca gatttttcaa
     1981 gtttttgatc ttttctttct cattctttag ccttttcttt atctttaaaa aaatccttct
     2041 gatctttcta taggagcctt gtaagtagta ttacaaactt ttccactata gctttgtaaa
     2101 tcttgtgcat aaatgttatt aggtaacaaa ctacctaaag ttagatataa tatcaacaat
     2161 atagatatac aattactaat acttttatgt ttcctaaatt ttttcattta ttctccctac
     2221 aaatattagt ttagttaact tttgaatttt aatttattta gattatataa tctaaataag
     2281 aattttttat ataaatttca taaaatatgt aggtatatat cataaaaata tgtatttata
     2341 tgatatgtca gtacaaaata acaactgaat attttaaaga gactatttcg tacttttatg
     2401 atttaatgag ctatcttatc gaatcataat ctaggaacaa ttgttataat atctaatagt
     2461 agttatatat gatatagtca gtatgtgttt tttcacaata tgattattat atagaggatt
     2521 cttagggatt actctttttg tataaaaaag agatggttca aatttttatc ttgagacatc
     2581 tcctttttct atttattatg ttttaataat attctttaaa atatttctat atgtattaga
     2641 tatacgacat atatggccat tactcatttt aatattattt ttctttaggt cgagagaaac
     2701 aatatgatat ttattaacta caaaagattt atgtacacgg ataaagcatg catctaaatc
     2761 tggtaaagac tttaaacttt tatagaattc aaatattcta gaagtagtca ctaattttat
     2821 tttatgtgga atagtgcttg tttcaaaata tataacttca tcaaatgaaa ttttccatag
     2881 tgagaaatct gaatagatag taaaaaaatt agagcgataa tttttttctt taatgtatct
     2941 tttgtgagca attttaatac aagcttttat tttactttca gcaatttcca tatcatgttt
     3001 tagtataaag tccataactt ctaacctata atcgaagatc cctaaaatca tttctatatg
     3061 atttgtaaga aatatgattg gactaatata atctgattct ctaatttttt gtgctatcca
     3121 taatccatca cataattcat tacttatctt atattttgcg tctacaacta taaaatatat
     3181 tcttacttta tttttttcag taagctcttt taataacaaa tttgcattat gatataatct
     3241 tacaacatca ttatcaaaac cttcttttat taaaatatta tttatttttt cttttagttt
     3301 cattccaaaa caaacatcat tatcaaagat taatatatcc actaaatacc ctcctataaa
     3361 aaattcaaaa gtaaaaaaac aaaagtattt tatagaaaat acataaaata acactaggag
     3421 ataaataaga ttaaggatag ttagaattaa ggtatattta tg
//
LOCUS       DAMKNB010000173         3222 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.179, whole genome shotgun sequence.
ACCESSION   DAMKNB010000173 DAMKNB010000000
VERSION     DAMKNB010000173.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3222)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3222)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3222
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.179"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            complement(<1..1257)
                     /locus_tag="PC494_003615"
     CDS             complement(<1..1257)
                     /locus_tag="PC494_003615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HDF3914064.1"
                     /translation="MLKVLKGNIIFTKTSETFTVFENSYIILEKGKVKGIFKEIPKEY
                     KNLKVVDYTDKLIIPGMNDLHAHASQFKNLGMAMDKELLPWLETYTFPEESNYKDIEY
                     ATKMYKKFVKELWKSGTTRIAVFATVHKEASMKLMDIFKEVGLGAYVGKVNMNMNCPD
                     TLLENTQDSITDTEEIINKYSDTDSIVKPIITPRFIPSCTSELLKGLGDLCLKYNIPI
                     QSHLSENYDEIEWVRSLEPESKFYGDAYNRYNLFGQTPTLMAHCVHCSQDEIDLMREN
                     NVMAVHCPASNFNVGSGAMPIRKLIDNNIRLALGSDISGGHTLSIFKAMVSAIQLSKL
                     YWVNSGKKYNFLSLSETFYIATKSGGSFFGKVGSFEEGYDFDALIIDDSNLNHDNYSI
                     LERLERFIYVGDDRNIIHRYVCGKLIE"
     repeat_region   1904..3119
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=1904..1932
                     /rpt_unit_seq="gttttatattaactaagtggtatgtaaat"
BASE COUNT         1132 a          394 c          423 g         1273 t
ORIGIN      
        1 ttcaattagt tttccacata catatctatg aatgatattt ctatcatcac caacatagat
       61 aaatctttca agtctttcaa gtatagaata attgtcatga tttaaatttg aatcatcaat
      121 aatcaatgca tcaaaatcat aaccttcttc aaagctacca acttttccaa agaaacttcc
      181 accacttttg gttgcaatat aaaaagtctc agataaagat aagaaattat acttcttacc
      241 agagttaacc caatataatt tagataattg tattgcagat accattgctt taaatattga
      301 caatgtatgt ccaccactta tatctgatcc aagtgctaat ctaatattat tatcgattaa
      361 ttttctgata ggcatagcac cactaccaac attaaagtta gaagctggac agtgaactgc
      421 cataacatta ttttctctca ttaaatctat ttcatcctga gaacaatgaa cacaatgagc
      481 cattaaagta ggagtttgac caaataaatt atatctatta tatgcatctc catagaattt
      541 agattcaggt tctagacttc taacccattc aatctcatca taattttcag ataagtgtga
      601 ttgaatagga atattatatt ttaaacataa atctcctaaa ccttttaaaa gttcacttgt
      661 acagcttggt ataaatctag gtgttattat tggttttaca atagaatctg tatcactata
      721 cttatttata atttcttctg tatcagtaat agaatcctga gtgttttcta ataaagtatc
      781 agggcaattc atattcatat ttactttacc aacgtatgct ccaagaccaa cttctttgaa
      841 tatatccata agtttcatag aggcttcttt atgtactgtt gcaaacactg ctattcttgt
      901 agttccagat ttccaaagtt cttttacaaa ttttttatac atttttgttg catattctat
      961 atctttataa tttgattctt ctggaaatgt ataagtttca agccatggca aaagctcttt
     1021 atccatagcc attccaagat ttttaaattg agaggcatgg gcatggaggt cattcatacc
     1081 aggtattata agcttatcag tgtaatctac tacttttagg tttttgtatt ccttaggtat
     1141 ctctttaaat attcccttta ctttaccttt ttccagtata atataactat tttcaaatac
     1201 tgtgaaagtt tctgaagttt ttgtaaaaat tatatttcct tttaatactt ttaacatata
     1261 ggtctcctta gttttaaatt tgttttaata tatgtaggta aaattttgtt ttacaaatca
     1321 aaattttacc acatgtatta tatcaaatct aaactataaa tactattaga taatagcaaa
     1381 tattagtgaa atacagttgt ttactattat tatatataac tgacatttaa gtgacattta
     1441 agaaaaatat aatgcctact tacataaaat ggaatgttat ttaaagagaa ctttgattat
     1501 attttcagaa gcttttttat ccatatcgtt taaaatatga gaatatctat ttatagttat
     1561 ttttatatta gtatgtccta atctttcaga gatgattttt atattagttc tagctagaag
     1621 aagaactatt agaatagata atatagtaag tatttacaaa tatgtaggtg ttcttaaatt
     1681 gataaattat tccattttaa ttttatagtt tgaattttat gatataataa aaatatataa
     1741 attttgcagt gagcgatatt tttgataaag tagggtttaa cagttgcaat gtaagggatt
     1801 gagggtgtat gataaatgtt atcaattgca ctactcatgg ttcactgcaa atttgagaga
     1861 gttgtatgtg tgtaagtact gaaaatactt agtttatttt ggggttttat attaactaag
     1921 tggtatgtaa atagaattta gtactttcta aaaatggatt gcctagcaag ttttatatta
     1981 actaagtggt atgtaaattt tcctaattcc ctatggtgta gcattggttg atagagtttt
     2041 atattaacta agtggtatgt aaatatatta aagatatgac actcttttat ataaaatata
     2101 agttttatat taactaagtg gtatgtaaat acaagttcag tagggagaca gacagtaatt
     2161 ttaaaagagt tttatattaa ctaagtggta tgtaaatcac aacaatacaa ataaaactct
     2221 gaaaaggtaa aagttttata ttaactaagt ggtatgtaaa tttattatta ttatatatct
     2281 tgacttagca ctatttttgt tttatattaa ctaagtggta tgtaaatatt actttgaaag
     2341 cattaacaga aaaagagatt agtaagtttt atattaacta agtggtatgt aaattattta
     2401 ctgttgaacc tacatcttga ttggataaaa agttttatat taactaagtg gtatgtaaat
     2461 taaggtttta atttattagt aataaatata agacctagtt ttatattaac taagtggtat
     2521 gtaaataatt ctttgactgc atcatttaaa taatctagct gagttttata ttaactaagt
     2581 ggtatgtaaa ttctaaaagg tcacatatat ttattaaatc tgttgccggt tttatattaa
     2641 ctaagtggta tgtaaatcat ataatgaatt acataacatc ttatgatatt catcgtttta
     2701 tattaactaa gtggtatgta aatttcatag tctttagagt ctgtaaatac tttactcata
     2761 gttttatatt aactaagtgg tatgtaaatt tactttaaaa tatgtaccat aaaaaaatat
     2821 atcaagtttt atattaacta agtggtatgt aaatatctct ggcgtataac cttcttttcc
     2881 tattagttct ggttttatat taactaagtg gtatgtaaat agggtttctg ataaaatctt
     2941 caaacatgta aaatatgtgt tttatattaa ctatgaggta tgtaaatctt atacttagtt
     3001 agaactatat atcgacacaa atatgcttta tattaactat atggtatata aattgcaatt
     3061 tttattcgtt gtccaatcgc tttgaaattt gttttatatt aactaagtgg tatgtaaatt
     3121 tgcaacaagt ataggtaaaa taccccaata atttatacag cattttctcc tttaaaatat
     3181 aattattttt tatcatttgt agtaaataat taccacataa ta
//
LOCUS       DAMKNB010000174         3199 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.180, whole genome shotgun sequence.
ACCESSION   DAMKNB010000174 DAMKNB010000000
VERSION     DAMKNB010000174.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3199)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3199)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3199
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.180"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            6..617
                     /locus_tag="PC494_003616"
     CDS             6..617
                     /locus_tag="PC494_003616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA pyrophosphatase"
                     /protein_id="HDF3914065.1"
                     /translation="MINDIKNKFKNYKPYINGYKNMKRASVLIPIVEINNTHYILFEV
                     RSKNLKHQPSEISFPGGKIESGETPYEAVIRETCEELGTFSDNIEVISSLDLLITPVK
                     FIIHPYLGYIKNINNLNINKDEVDHTFLVPIKYLLENPPNTYSNTVKVFPDENLPYGS
                     IPNQKDYKFESGSYPILFYKYKDYVIWGMTAKILENFLNFLSE"
     gene            915..1253
                     /locus_tag="PC494_003617"
     CDS             915..1253
                     /locus_tag="PC494_003617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3784 domain-containing protein"
                     /protein_id="HDF3914066.1"
                     /translation="MFAVGFVVIIALAFFILSVLLFNGKASMLLAGYNSMSKKEKARY
                     DKKKLCRSSSIVTFIVSIMLFIMAFLGYRIESGQMDEKKMVPFSIIFIIVILSSVFFN
                     ILYSNKKCKK"
     gene            complement(1660..3096)
                     /gene="miaB"
                     /locus_tag="PC494_003618"
     CDS             complement(1660..3096)
                     /gene="miaB"
                     /locus_tag="PC494_003618"
                     /EC_number="2.8.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (N6-isopentenyl
                     adenosine(37)-C2)-methylthiotransferase MiaB"
                     /protein_id="HDF3914067.1"
                     /translation="MSKRKQVTIPIEKIQEQDKYIEQIHRQNEEYFNRTGKRKLVFTQ
                     TFGCQMNEHDSEKLCSMLEEMGYQMSMMVEESDLIIYNTCAVRENAELKVYGNLGQLK
                     HLKGKNPDMKIAVCGCMMQQPHVVEELRKKYKHVDLIFGTHNLYKFPQLLTESINSDK
                     MLVDVWDVDGEVIEGLRSNRKFELKAFVNIMYGCNNFCTYCIVPYTRGRERSRTPEDI
                     INEIKELVANGTKEITLLGQNVDSYGKTLENPVSFSELLRKVNDIEGIERVRFMTSHP
                     KDISDEVIYAIRDCDKVCEFLHLPIQCGSSSLLKKMNRHYTKEYYLEIIEKAKKEVPG
                     IAFSTDLMIGFPGETEEDLLDTLDVVEKVRYDSAFTFIYSKRQGTPAAKMENQIPEDI
                     KHDRFNRVLEAVNRISAEINDGYKDRIVEVLVEGRSKNNENKFAGRTRQNKLVNFEGG
                     NDDLIGKLVMVKITEPRTFSLNGILVNN"
BASE COUNT         1097 a          474 c          367 g         1261 t
ORIGIN      
        1 taaaaatgat aaacgatatt aaaaataaat tcaaaaatta caaaccatat ataaatggat
       61 acaagaatat gaagagagca tctgttttaa ttccaatagt agaaataaat aacacacact
      121 atatattatt tgaagttcgc tcaaaaaatt tgaagcatca acctagtgaa atttcttttc
      181 caggtggtaa aatagaatca ggtgagactc catatgaagc tgttattaga gaaacttgtg
      241 aggaacttgg aacttttagt gacaatatag aagtaatatc aagtcttgac ctccttataa
      301 caccagtaaa gtttatcata catccatact taggatatat aaaaaatatt aataatttaa
      361 atataaacaa ggatgaagtt gaccatactt ttttggttcc tataaaatat cttttagaga
      421 atcctccaaa tacttatagt aatactgtaa aagtttttcc agacgaaaat ctaccatatg
      481 gttcaattcc aaaccaaaaa gattataaat ttgaaagtgg aagttatcct attctgtttt
      541 ataaatataa agattatgta atttggggaa tgacagcaaa aatactagaa aactttttaa
      601 attttttatc agaataacac tcataataaa tcatcaaaac ttttacataa gaaatttata
      661 aaagtttcta aatttaacaa ttctaaaata tcaataacta tattttgtag cactttttta
      721 ttttattatt gtttgaatat ttgatggttt tcaatgcaat ttcaacataa atactatgta
      781 ttagtgtata ctgttgatga attaaagtat gataatctat ttaataaagt atgaagtaaa
      841 tgattttaat gtgcctttat ggtaaaatta ctaataagta ataaaattaa ttaaaatata
      901 tggaggtgct tataatgttt gctgtaggat ttgttgttat aattgcactt gcctttttca
      961 ttttaagtgt actattattt aatggaaaag ccagtatgct actagcaggt tataactcta
     1021 tgagtaagaa agaaaaagca cgatacgata aaaaaaaatt atgtagaagt tctagcattg
     1081 ttacttttat tgtctctata atgctattta ttatggcgtt tttgggatat agaatagaga
     1141 gtggtcaaat ggacgaaaaa aaaatggttc ccttttctat aatatttata atagtcatac
     1201 tttccagtgt attttttaat atcctctact ctaacaaaaa atgtaaaaaa taaatagttg
     1261 taagttgagc agttaattat aaaagattga ctgctttttc atgtatattg actactctta
     1321 ttaaatattt taacatttaa aaatctatgt aaaaataatg aatatagtac aaacttctaa
     1381 taatgatttt acctttgtgg ttacagtcca ctatatataa tttaatatga taacagggaa
     1441 ttactaatga caactaggta agcttttata aaatataata aaacaaaaat agatgtacaa
     1501 tgaaattata tcttatatca aatttatttt tattaatagc aaaaacttac attagcataa
     1561 catatgacaa attcgcttaa aataaaaatt tttaatataa tttgttctat agtacatcta
     1621 ttttgattag tttacataat tttattattt tgtacaatat taattattta ctaatatccc
     1681 atttaatgaa aaagttctag gttcagtaat ttttaccata actaatttac caattaaatc
     1741 atcatttcca ccttcgaaat ttacgagttt attttgtcta gttctaccag caaacttatt
     1801 ttcattattt ttacttcttc cttcaactag aacttcaact attctatctt tatatccatc
     1861 atttatttct gcagaaatcc tatttacagc ttctaacacc ctattaaatc tatcatgctt
     1921 tatatcttct ggtatttgat tttccatttt agcagcagga gttccctgtc ttttagaata
     1981 aataaatgta aaagctgaat catatctaac tttttcaacc acatctaaag tgtccaataa
     2041 atcttcttct gtttctcctg ggaaaccaat cattaagtct gtagaaaaag caatacctgg
     2101 aacttccttt ttagcttttt ctattatttc taaataatat tcctttgtat aatgtctatt
     2161 catttttttc aaaaggctac tgcttccaca ttgtattggt agatgtaaaa actcacacac
     2221 cttatcacaa tctctaattg cgtatattac ttcatcagat atatcttttg gatgagatgt
     2281 cataaatcga accctttcaa ttccttctat atcattcact tttcttaaaa gttctgagaa
     2341 tgaaactgga ttttcaagtg tcttaccata agaatctaca ttttgtccaa gtaaagtgat
     2401 ttctttcgtt ccatttgcaa caagctcttt tatctcgtta attatatctt caggagttct
     2461 acttctttct cttcctcttg tgtatgggac tatacaatat gtgcagaaat tattgcatcc
     2521 atacattata tttacaaatg cttttaattc aaattttcta ttacttctaa gaccttctat
     2581 tacttctcca tccacatccc atacatccac taacattttg tcagaattta ttgattctgt
     2641 aagtaattgc ggaaatttat atagattatg tgttccaaat ataaggtcta catgtttata
     2701 tttttttctt aattcctcta caacatgtgg ttgttgcatc atacatccac atacagctat
     2761 tttcatatct ggattttttc cttttagatg ttttaattgt cctaagttac catacacttt
     2821 tagctctgca ttttctctaa ctgcacaggt gttatatatt attaaatcac tttcttcaac
     2881 catcattgac atttggtatc ccatctcttc taacattgaa cataattttt ctgaatcatg
     2941 ttcattcatt tgacacccga aggtttgagt aaacacgagt tttctctttc cagttctgtt
     3001 gaagtattct tcattttgtc tgtgtatttg ttctatatat ttatcttgtt cttgtatttt
     3061 ctctataggt attgttactt gttttctttt gctcacgtct attcctccta gttaatttct
     3121 tatattacac ataaccttaa ttatatcaaa taagaaaaat cttttaaaga tattattatt
     3181 tttctagttg tgttttaat
//
LOCUS       DAMKNB010000175         3029 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.181, whole genome shotgun sequence.
ACCESSION   DAMKNB010000175 DAMKNB010000000
VERSION     DAMKNB010000175.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3029)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3029)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3029
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.181"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            92..2449
                     /locus_tag="PC494_003619"
     CDS             92..2449
                     /locus_tag="PC494_003619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IC family P-type ATPase"
                     /protein_id="HDF3914068.1"
                     /translation="MDKVNLERYSCDINVGLNKNQLQSRIDDNLINAFDNGKTKTYKQ
                     IFKDNIFTLFNLINIVLVCLLVSVGSFKNTLFIFIAVINTIIGVIQEIRAKRLLDNLS
                     VIVSNKVSVIREKEKKEIDVQELVLDDIMILKTGNQICADSKVLNGKLEVNESLVTGE
                     SDIIIKNKGDFLYSGSFVVSGEAFVRVENIGKDNYANKIANDAKISKKHNSQLRNSLN
                     AILKIVGIIIIPLGIILFAKQHFGNGDSIATSVVGTVAAVNGMIPEGLTLLTSIALAV
                     GTIKLASHKTLVQELYCVETLARVDTLCLDKTGTITEGKMQVDDIVMLEEVDINEIMG
                     NICNSLKDDNATLNAIRDKYNVLDTYKAKNLIPFSSERKYSGVTFENKGTYLLGAFEF
                     IFKEKNKKLRIEVERYSKKGNRVIVLAHSDSYMEDDNIPEDIKPLAFILILDKIRDEA
                     KETLEFFYNEGVDIKIISGDNPITVSEVARKAGLKTASNFIDATTLKNDSDIYKAVDK
                     YSVFGRVSPQQKKQMILALKKQNHTVAMTGDGVNDVLALKEADCSIAMASGSDVTKNV
                     SNLVLLDSNFASMPKVVMEGRKVINNIQRASSLFLVKTIFSFFLSLLTLFFFSRQYPF
                     VPIQLSLIGAVTVGIPSFFLALEANKSRISGNFLLNILKNALPGALCVTVNVIIVYNI
                     VEYLGYSSSVFSTMCAILTGVCGLLILRQQCLPFNKERLFLIVSMTIAFVIGILFLGG
                     LFSFVALSRELILITMALAILMPIMIKVMLFVLDEILETIVPDLN"
     gene            complement(2535..2852)
                     /locus_tag="PC494_003620"
     CDS             complement(2535..2852)
                     /locus_tag="PC494_003620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine/purine nucleoside phosphorylase"
                     /protein_id="HDF3914069.1"
                     /translation="MSEFKNVTAVKKANVYFDGKVSSRVIILPNGERKTLGLMLPGEY
                     TFSTREEEIMEMLAGSMDVKLPGSNEFVTYKEGQKFNVPSDSSFDLKVNEVVDYCCSY
                     IAD"
BASE COUNT         1161 a          332 c          494 g         1042 t
ORIGIN      
        1 actatagaat aataaaataa aaaaattgag aattttataa tatatttgta gatttgagta
       61 taaaaaagtg ctaagttgaa aggagtaaaa tatggataag gttaatttag aaaggtatag
      121 ttgtgatata aatgttggtt taaataaaaa tcaacttcaa agtagaatag atgataattt
      181 aattaatgca tttgataatg gaaaaaccaa aacatataaa caaattttta aagacaatat
      241 atttacactt tttaatctca taaatattgt tttagtctgt ttattagttt cagttggttc
      301 ttttaaaaat accttattta tatttattgc tgtaattaat actattatag gagtaataca
      361 agagataaga gctaaaagat tattggacaa tctatctgtt atagtttcaa ataaggtatc
      421 tgtcataaga gaaaaagaga aaaaagagat tgatgtacaa gaattagtat tagatgatat
      481 tatgatttta aaaacaggta atcaaatttg tgcagattca aaagttttaa atggaaaatt
      541 agaggtaaat gagtccttgg ttacaggtga atctgatatt attataaaaa ataaaggcga
      601 ttttttatat tctggaagtt ttgtagtttc tggagaagct tttgtaagag ttgaaaatat
      661 aggaaaagat aactatgcaa ataagatagc taatgatgca aagatttcta aaaaacataa
      721 ttctcaactt agaaattcat taaatgcaat attaaaaatt gtaggtataa taataattcc
      781 tctaggaatt atattgtttg caaaacaaca ttttggaaat ggagattcta tagctacatc
      841 tgtagtaggt acagtggcag ctgtaaatgg tatgatacca gagggattaa cattacttac
      901 gagcattgct ctagctgtag gaactataaa acttgctagt cataaaactt tagtgcaaga
      961 actgtactgt gtagagactc ttgctagagt tgatacacta tgtcttgata agacaggtac
     1021 aattacagaa ggtaaaatgc aagttgatga tatagtaatg ttggaagaag tggatattaa
     1081 tgaaataatg gggaatatat gtaattctct caaagatgat aatgcaacac taaatgcaat
     1141 aagagataag tataatgttt tagatacgta taaagctaag aatttaatac cattttcttc
     1201 agaaagaaaa tacagtgggg ttacctttga aaataaaggt acatatttat taggtgcatt
     1261 tgagtttata tttaaggaaa aaaataaaaa acttaggata gaagttgaaa gatattctaa
     1321 aaaaggaaac agagtaatag ttttagctca tagtgattct tatatggaag atgataatat
     1381 tcctgaagat ataaagccac tagcttttat attgatattg gataaaatta gagatgaagc
     1441 taaggaaact ttagaatttt tttacaatga aggtgtagat ataaaaatta tatctggtga
     1501 caatcctata acagtaagtg aggtagctag aaaagcaggt cttaaaacag ctagtaattt
     1561 tattgatgca acaacactta aaaatgatag tgatatatac aaagcagttg ataaatacag
     1621 tgtttttgga agggtaagcc cacaacagaa aaaacaaatg attttagcat taaaaaaaca
     1681 aaatcataca gtagctatga ctggagatgg tgtaaatgat gtgctagcac ttaaagaagc
     1741 ggattgtagc attgccatgg catctggaag tgatgttact aagaatgtgt ctaatttagt
     1801 cttattagat tcaaactttg catcaatgcc aaaggttgtt atggagggaa gaaaagtaat
     1861 taataacatt caaagagcat cttctttgtt tttagtaaag acaatttttt cattcttctt
     1921 gtcgttatta acattattct tcttcagtag acagtatcca tttgttccta tacaattatc
     1981 actcattggg gctgtaacag tgggtatacc atcattcttc ttagctcttg aagcaaacaa
     2041 aagtagaatt tcaggaaatt ttttactcaa tatattaaaa aatgctttac caggagcact
     2101 atgtgtgaca gtaaatgtaa ttattgttta caatatagtt gaatatttgg gttatagttc
     2161 aagtgtattt tccacaatgt gtgctatatt aactggtgta tgtggtcttt taatattaag
     2221 acaacaatgt ttgccattta ataaagaaag attattttta atagtaagta tgactattgc
     2281 atttgttatt gggattctat ttttaggtgg attattctca tttgtagcat tgagtagaga
     2341 attaattctc ataactatgg cattagcaat attaatgcca attatgataa aagttatgtt
     2401 atttgtctta gatgagatat tagagacaat tgttccagat ttaaattaat tttaaaatga
     2461 tataaataag agcagtttta gttgaactgc tctttttaga tgtgtttaat tttatgtaag
     2521 aatatgtatt tttattaatc agctatatat gagcaacagt agtcaacaac ttcattaacc
     2581 tttaagtcaa aacttgaatc actaggaaca ttaaattttt gtccttcttt gtaagttaca
     2641 aactcattgc ttccaggcag ttttacatcc atacttccag caagcatctc cattatttct
     2701 tcttctctag tagaaaaagt gtattctcct ggcaacatta atcctaaagt ttttctttct
     2761 ccattaggca gtattattac tctgctactt accttaccat caaaataaac gtttgccttc
     2821 tttactgcag taacattctt aaattcactc attagataaa acctccaaaa ttatttgtac
     2881 atatatatta tataaaaata atgtaaaaaa tgctatatat ttacaaaaaa atttagtatt
     2941 tattaaaaaa attaataaga ataaaaaaga gatggaattg cttaaattga taaaaaatat
     3001 aaaataaatt gcaaagtaag caagaaaag
//
LOCUS       DAMKNB010000176         3023 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.182, whole genome shotgun sequence.
ACCESSION   DAMKNB010000176 DAMKNB010000000
VERSION     DAMKNB010000176.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3023)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3023)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3023
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.182"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            163..1056
                     /locus_tag="PC494_003621"
     CDS             163..1056
                     /locus_tag="PC494_003621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HDF3914070.1"
                     /translation="MKNKKFIVIILIISILIGVLVKEYSSREIKKDDINVSKYIKYAD
                     LASKNNAQVNWKYVASIVAVLNKNNLKNVKDSQIQEVSDLFVKNFSKNNKINKLSDIL
                     DELEFSNRQKRLVDNYIDNLKDYGIKPERLKSDTKYMKFIDEIKTEAIQNYKDYKILP
                     SITIAQAIIESSWGKSTLAKQYSNLFGIKADAYWKGKSVTLETKEHLDTIIDDKFRIY
                     DDKNESIKDHAKFLATNKRYKNNGVFDAKTYIYQAKALEKAGYSTAKDENGNSIYAAR
                     LIELIQQYNLQLIDSEIQSEM"
     gene            1493..1984
                     /locus_tag="PC494_003622"
     CDS             1493..1984
                     /locus_tag="PC494_003622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3914071.1"
                     /translation="MYENNKVIYNLERCEKLEKTLYLSQFNTYKNFKLASKKTVINSL
                     ETYVYNMNINNISLVDTIECISLEYEQLTGKKLILVGDIDIDAILDYAGNKRNRNSSK
                     KNTFKLKIPFSTFIQMPRKIENKDKINLKYLIQDITSSILDDNLFISVTAIISYENSS
                     KIE"
     gene            2012..2959
                     /locus_tag="PC494_003623"
     CDS             2012..2959
                     /locus_tag="PC494_003623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3914072.1"
                     /translation="MRITKTTFNDVFSNDANGSIIKVEKYVDKKCASVFEILTYTIIV
                     TNTSRYKTGNIFFKDYISKYIEFINNTVKVNGIIKRGLDPQQGFYIGRIDASCKKIIS
                     FKSVVLPNSAHRIIKNSANIYYYYKCNLDKFPTRISIESNRVYTNVNKIVFKQLNISN
                     TLKAPKNLRDILKVNVNSKIFDVKPMKNLINKGSNLKLCNLIVFGCIEVEIDYSCKNR
                     SNFKTVNKSNDIKKDKYYKNDIQNNNENINDCKKQISFGDNKVKKITKTFGFSCFICS
                     PVGIIYEDMKNINIKIEHTSINELNPEELFVNTSLLLYY"
BASE COUNT         1323 a          265 c          426 g         1009 t
ORIGIN      
        1 aactattttg tgtgatagaa aactatatat tataacaata gtagtgcttt taattaaata
       61 tatttcataa atcttcataa aatcttcaaa atttcgtaaa gaatatgtca caaaagtaag
      121 gtatattata ttcagcagat agtataaggg aggacaatat ttatgaagaa taaaaaattc
      181 attgttataa tactgataat atcaatttta ataggtgtat tagtgaagga atattcatct
      241 agagagataa aaaaggatga tataaatgtc agtaagtata taaaatatgc tgatttagca
      301 agtaaaaata atgcacaagt taactggaag tatgtagctt ccattgttgc tgtgttaaat
      361 aaaaataact taaaaaacgt taaggattca cagatacaag aagtatcaga tttatttgtt
      421 aagaattttt ctaaaaataa taaaataaat aagttaagtg atattttgga tgagttagaa
      481 tttagtaata gacaaaaaag attggttgat aattatatag acaatcttaa ggattatggt
      541 ataaaaccag aaagattgaa gtctgataca aaatatatga agtttattga tgaaattaaa
      601 acagaagcaa tacaaaatta taaggattat aaaatacttc catctataac tattgcacaa
      661 gctataatag aatctagctg gggcaagtca actttggcaa aacaatatag caatctattt
      721 ggtataaagg ctgacgctta ttggaaaggt aagtcagtga ctttagaaac gaaagaacat
      781 ttagatacaa ttatagatga taaatttaga atatatgatg ataaaaatga atctataaaa
      841 gaccatgcaa aatttttagc cacaaataaa aggtataaaa acaatggtgt atttgatgca
      901 aaaacgtata tatatcaagc taaagcatta gaaaaggcag gttatagtac tgcgaaggat
      961 gaaaatggca atagtatata tgcagctcgt ctaatagaat taattcaaca gtataatctt
     1021 caattaatag acagtgaaat tcaaagtgaa atgtaacttt gattaaattt ttattgataa
     1081 ggctatgatt tttaaaatca tagccttatt ttgacatgct tttacttgta attattaaat
     1141 cgatatcatt atctttcaaa atttacttta tactgtaaat caaattattt aagttaaaac
     1201 ttggaattat ttataaaagg attatttact ttatctaaat tctgcactta aagaacatct
     1261 tttcccttaa gactgaccgt tagtctataa aaattataat tacttataaa aaagtgaata
     1321 tatatataaa gttttcagaa agacttttac ttgtaaattg aaatcaatga agtaaaaaag
     1381 gattctttct taaaagtaaa taacaactag atagtgaata ataaaaaatg gtaatttgaa
     1441 ataattttta tgaatagtat taatatatag atacagggag attgatgcga ttatgtatga
     1501 aaataataag gtaatataca accttgaaag atgtgaaaaa ctagaaaaga ctctttattt
     1561 atctcaattt aatacatata aaaattttaa attagcttct aaaaaaactg taataaattc
     1621 attagagaca tatgtttaca atatgaatat taacaatata agtcttgttg atactataga
     1681 atgtatatca ttagaatatg aacaacttac aggaaagaag ttgattttag ttggtgatat
     1741 agatattgat gcaatattag attatgcagg aaataaaaga aatagaaatt ctagtaaaaa
     1801 aaatacattt aaattaaaaa taccctttag tacatttata caaatgccta gaaagataga
     1861 aaataaagat aaaattaatt taaagtatct tatacaagat attacttcat ctattttaga
     1921 tgataattta tttattagtg ttactgcaat tataagttat gaaaatagtt ccaagataga
     1981 gtaatcttta aattatagaa aggtggatgc aatgagaata acgaaaacta cttttaatga
     2041 tgtattttca aatgatgcaa atggaagtat tataaaagta gaaaaatatg ttgataaaaa
     2101 atgtgcatct gtatttgaga ttttgaccta cactattatt gttacaaata caagtaggta
     2161 caaaactgga aatatatttt tcaaagatta tatttctaaa tatatagagt ttataaataa
     2221 tactgtaaaa gttaatggca ttataaaacg tggattagac ccacaacaag gtttttacat
     2281 agggagaata gatgcaagtt gtaaaaaaat aatatctttt aagagtgtag ttttaccaaa
     2341 ttctgcacat aggattataa agaatagtgc taatatatac tattattata agtgtaatct
     2401 agataaattc ccaacaagaa tatcaataga aagtaataga gtttatacta atgtaaataa
     2461 aattgtattc aaacaattga atataagtaa tactttaaaa gctcctaaaa atctaagaga
     2521 tatattaaaa gtaaatgtaa atagtaaaat atttgatgtt aaacctatga aaaatcttat
     2581 aaacaaaggt agtaatttga aattatgtaa cttgatagtt tttgggtgta tagaagttga
     2641 aatagactat agttgtaaaa ataggagtaa ttttaaaaca gtaaataagt ctaatgacat
     2701 taaaaaagat aagtattata aaaatgatat acaaaataac aatgaaaata taaacgattg
     2761 taaaaagcaa ataagttttg gtgataataa ggtaaaaaaa ataacaaaaa cttttggatt
     2821 ttcttgtttc atttgttctc cagttggaat tatttatgaa gatatgaaaa atataaatat
     2881 aaaaattgaa catacatcaa taaatgaatt aaatccagaa gaattatttg taaatacatc
     2941 acttttattg tattattaag tattttaaag ctaaaactta aacttattaa aatagcattt
     3001 ggttaaagga aaatagatat tga
//
LOCUS       DAMKNB010000177         2864 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.183, whole genome shotgun sequence.
ACCESSION   DAMKNB010000177 DAMKNB010000000
VERSION     DAMKNB010000177.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2864)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2864)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2864
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.183"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            378..2189
                     /locus_tag="PC494_003624"
     CDS             378..2189
                     /locus_tag="PC494_003624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional diguanylate
                     cyclase/phosphodiesterase"
                     /protein_id="HDF3914073.1"
                     /translation="MKKKYDFLIYSAIWLVIIILFIFSLYHSIEHIKIISHTGTIRSE
                     TQKVVKQELNNERNDDLIKRLDNILIKLRTGNGENGFQRCDNKEFQQKLNQMDSMWES
                     MKKEIIKVRNGASGDKLYKLSEEYSVLSNQIVFISEKHSNAKLYSFATALFIYLIFST
                     ISLLIWEYYNKKRFKRIFYTDNLTKIKNQVAFENRAIEILHNASNKEYVLLNIDIDNF
                     KYINDTHGYEYGDKVLIIVAAALSKTFNIKETCARIGSDNFVILAKYRDSLLEDIREM
                     LTNAIISELDMNVTQTISYCIGAYLVEIDNLGYKSINSIMDKANIAHKVSKTRGISST
                     VWYNENLLKQLQMENSIYNYMYKAIENEEFHMYLQPKFQISSLNVVSAEALVRWFSPE
                     LGFLSPDEFIPLFEKSGFIIELDFYMLKKACSFVRKTFMKKNQYTYPIAVNFSRVTIY
                     QNSFYQRFLDTVKEYEIPFKYIEIEVTESAFNEISQPVISILEELKKLGFLISMDDFG
                     SGYSSLSLLCSLSINGLKLDKSLLKETFNREKVYSIIQCIIEMSHRIGMSVVCEGIET
                     KKDLEFLNTVKCDVGQGFYFSKPIEEKEFFNKYVTKK"
     gene            complement(2277..2858)
                     /locus_tag="PC494_003625"
     CDS             complement(2277..2858)
                     /locus_tag="PC494_003625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3914074.1"
                     /translation="MLYLLKINQFEKSYDIGIFKNEQSIYKFIAKIPFVKKDNSNFNY
                     TNYYMEFEDIPEYYEVNFNNYLYIITRFSFIPDGTEIFFTWEEIHCWDEKVATEKTFI
                     NGETLVDSYNFPNNEVKDYIQKRESLYIETKKYYEEKGLKIERHALGSEDGEYVELTN
                     DSILYLLDIEAVEIREQSKNIEEFLYKYKKRFK"
BASE COUNT         1080 a          297 c          406 g         1081 t
ORIGIN      
        1 gagttaaatt gtaggtaaat agtattttaa ttatttatta aaatatagat tatgtatatg
       61 ccaaatttaa aaagagacat aaagacatta tacaaatata ttattggggt gatattttat
      121 aagaaaagaa gtgatgcagt aaattaattg agcaatttaa aaatgattta atgatagtgt
      181 tgatgaatgt ttaaaaagaa attttagaaa aacgtatatt gctgtttgtg ttggaggtga
      241 tgaatttgta taatttatag gatataaatg attaaactat ttaagataaa tacatatcac
      301 tgtaaaatat tgataatcat tttttataag agattgatta tttgcaaatt atatatatta
      361 caaatgaggt aacaataatg aagaaaaaat atgatttttt aatttattct gctatttggc
      421 tagttattat tattcttttt atattttctc tatatcacag tatagagcat attaaaatta
      481 taagtcacac tggtactatt cgcagtgaaa ctcaaaaggt tgttaagcaa gaattgaata
      541 atgaaagaaa tgatgacttg ataaaacgac tggataatat tctgataaag ctaagaacag
      601 gtaatggaga aaatggattt caaagatgtg ataataaaga atttcaacaa aaactaaatc
      661 aaatggattc tatgtgggaa tctatgaaga aagaaattat aaaagttaga aatggtgctt
      721 caggtgataa attatataaa ttgagtgaag agtattctgt gttgtctaat caaattgttt
      781 ttatatctga aaaacactct aatgcaaaat tgtattcttt tgctactgca ctatttattt
      841 atcttatatt ctcaacaata agtcttttaa tttgggaata ttataataaa aaaaggttta
      901 aaagaatatt ttatactgat aatttaacaa aaataaaaaa tcaggttgca tttgaaaaca
      961 gagcgattga aattttgcac aatgcatcta acaaagagta tgtactgcta aatattgata
     1021 ttgacaattt taaatatatt aatgatacac atggatatga atatggagat aaagttctaa
     1081 taatagttgc agctgcactt tctaaaactt ttaatatcaa agaaacttgt gcaagaattg
     1141 gttcagataa ttttgtaata cttgcaaaat atagagattc tcttttagag gatattcggg
     1201 aaatgctaac taatgctata atctctgaat tagatatgaa tgtaactcaa actatatctt
     1261 attgtatagg agcgtactta gttgaaattg ataatttagg ttataaatcc atcaattcta
     1321 taatggataa ggcaaatatt gcacacaagg taagtaaaac aagaggaatt tcctccacag
     1381 tatggtataa tgaaaatctg ttaaaacagt tacaaatgga aaatagtatt tataattata
     1441 tgtataaagc gatagaaaat gaagaatttc atatgtattt gcaacctaaa tttcaaatat
     1501 cttctttaaa tgttgtaagc gcagaagctc ttgtaagatg gttttctcca gaacttggtt
     1561 ttttatcacc agatgaattt attccattgt ttgaaaaaag tggatttatt attgaattgg
     1621 acttttatat gttaaaaaaa gcgtgttcat ttgtaagaaa aacgtttatg aaaaaaaatc
     1681 aatatacata tccgattgca gttaattttt caagggttac tatttaccaa aatagttttt
     1741 atcaaaggtt tttagatact gttaaagaat atgaaattcc ttttaagtat atagagatag
     1801 aggtaactga aagtgctttt aatgaaatat ctcaaccagt tatttcaatt ttagaggaac
     1861 ttaaaaagtt aggattttta atttcaatgg atgattttgg ttcaggatac tcttcattaa
     1921 gtcttttatg ttctctatct attaatggat tgaagttaga taaaagctta cttaaagaaa
     1981 cctttaaccg ggagaaagta tatagtatta ttcaatgtat tattgaaatg tcacatcgta
     2041 taggcatgtc tgttgtatgt gaaggtattg aaactaaaaa agacttggaa tttttaaata
     2101 cagttaaatg tgatgtagga caagggtttt atttttctaa accgatagaa gaaaaagaat
     2161 tttttaacaa atatgtaact aaaaaataat ataattattt ttatcagtct atacattgag
     2221 tcattttata tctcgttaaa tgactcaatg tactgttatg tattttaaaa tataaattat
     2281 ttaaaacgtt ttttatactt atatagaaat tcttctatat tttttgattg ttctcttatt
     2341 tcaactgctt ctatatctag taaataaagt atagaatcat ttgtaagttc aacatattca
     2401 ccatcttctg aaccgagtgc atgtctctca atttttaatc ctttttcttc ataatatttt
     2461 tttgtttcta tatataatga ttctcgcttt tgtatgtagt ctttcacttc attatttgga
     2521 aagttatatg aatccactaa tgtttcgcca tttataaaag ttttctcggt agcaactttt
     2581 tcatcccaac aatggatttc ttcccaagta aaaaatatct cagttccatc tggaatgaat
     2641 gaaaacctgg taataatata taaataatta ttgaaattta cttcataata ttcaggaata
     2701 tcttcaaatt ccatatagta atttgtataa ttaaaattac tattatcttt ttttacaaag
     2761 ggtatttttg caataaattt atatattgat tgttcatttt taaaaattcc tatatcataa
     2821 cttttttcaa attgattaat ttttaataaa tacaacattc tttc
//
LOCUS       DAMKNB010000178         2856 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.184, whole genome shotgun sequence.
ACCESSION   DAMKNB010000178 DAMKNB010000000
VERSION     DAMKNB010000178.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2856)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2856)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2856
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.184"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            182..1105
                     /locus_tag="PC494_003626"
     CDS             182..1105
                     /locus_tag="PC494_003626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2520 domain-containing protein"
                     /protein_id="HDF3914075.1"
                     /translation="MGSGKVGTSLANYFLSKGYCVSGFYGRNQLSLLESTNLTKTKIY
                     SNLKDIIYENDILFITTSDDSIEIIDKKLSKFNLKHKYICHTSGSLKSSILFCSKKAG
                     ALIYSIHPIFAFSNKNTNIKKMKDICFSIEGDNEQDDLVIQNFIDDLGNQFFIRDKDT
                     SSTYHLANVLVSNLVLSLLDIGVSYFIKLGLSEEESLKAISPLVKKNIENILDNGFTK
                     ALTGPVSRGDITPIRKHLSVLDKKDEDIYKILSLNLLKIIALGNDNSLKGIKNITIEN
                     AIENLISKSEKYKEIYKLLGGKNDEKYHTDF"
     gene            1080..1907
                     /gene="panB"
                     /locus_tag="PC494_003627"
     CDS             1080..1907
                     /gene="panB"
                     /locus_tag="PC494_003627"
                     /EC_number="2.1.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011721175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-methyl-2-oxobutanoate
                     hydroxymethyltransferase"
                     /protein_id="HDF3914076.1"
                     /translation="MKNTIQTFKNAKYEGKKLSMLTAYDYSIAKIMDECDINGILIGD
                     SLGMVIKGEENTLSVTIDEIIYHTKAVKNGVKNALIVSDMPFLSYHVSIEDAVKNAGR
                     LIKEGGAHAVKLEGGSNVIKQIESIVNAQIPVMGHLGLTPQSVNSFGGFKVQGNTSET
                     ARQLIEDAKLIEKAGAFSIVLEGVPTKIAEMVTNSISIPTIGIGAGINCDGQILVYQD
                     MLGMFGDFVPKFVKQYANIGDIMKDSIKNYILEVNTGAFPQEKHSFSINESELEKLY"
     gene            1926..2774
                     /locus_tag="PC494_003628"
     CDS             1926..2774
                     /locus_tag="PC494_003628"
                     /EC_number="6.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantoate--beta-alanine ligase"
                     /protein_id="HDF3914077.1"
                     /translation="MLVKEIKLLRNIIKDWRKHGYSIGLVTTMGFLHEGHQSLIKKAI
                     KENDKVVVSVFVNPTQFGPNEDFNSYPRDIDKDFKYCMDSGATVVFNPSPEEMYLKGN
                     CTTINVSGLTDFLCGAKRPVHFGGVCLVVSKFLNIVTPDKAYFGEKDAQQLAVIKRMV
                     KDLNIDTEIIGCPIIRENDGLAKSSRNTYLSEEERKSALILNKSLSLAKEELVKGNLN
                     PENIKELIIAKINSEHLAKIDYVEIVDSETLQPVKQIEHSILVAIAVFIGKTRLIDNF
                     TFELNI"
BASE COUNT         1148 a          338 c          461 g          909 t
ORIGIN      
        1 agaattaatt gtcaattttt tatgaaaatg gtaagatatt tatggatggt atcttgttat
       61 aagaactata ctttaaatgt ttttaattat tttgtcttat gtaactcata tcctcaggaa
      121 tgagattaga aattaagatg ttgtatcaca aagtggaggt gatactatta aaataggctt
      181 tattggttct ggaaaagttg gaacatcttt ggcaaattat tttttatcaa aaggttattg
      241 tgtttcaggc ttttatggaa ggaatcaatt atctttatta gaatcaacaa atttaacaaa
      301 aacaaagatt tacagcaatt tgaaagatat aatttatgaa aacgatatat tatttattac
      361 aacatcagat gattctattg aaattataga caaaaaactt tccaaattta atttaaaaca
      421 taaatacatt tgccacacaa gtggctcttt aaaatctagt atattgttct gttcaaaaaa
      481 agcaggtgca ttaatttatt ctatccatcc tatatttgca ttttccaata aaaataccaa
      541 cataaaaaaa atgaaagaca tttgtttttc catagaaggt gataatgaac aagatgattt
      601 agttattcaa aattttatag atgatttggg aaaccaattt tttataagag ataaggatac
      661 ttcatccact tatcatttag ctaatgtttt agtttcaaat ttagtattat ctttactaga
      721 tataggagta agttacttta ttaaattagg tttatctgaa gaggaatctt taaaagctat
      781 cagtccttta gtaaaaaaaa atatagaaaa tatacttgat aatggcttta ctaaagctct
      841 tactggtcct gtttctcgtg gagatataac accaataaga aaacatctat ctgtattgga
      901 taaaaaagat gaggatattt acaaaatact atccttaaac ctactaaaaa taattgcctt
      961 aggaaatgac aattcattaa aaggtataaa aaatattact atagaaaatg caatcgaaaa
     1021 tttaataagt aaatctgaaa aatacaaaga aatttacaaa cttttaggag gaaaaaacga
     1081 tgaaaaatac catacagact tttaagaatg ctaaatatga aggaaaaaaa ctatctatgc
     1141 ttactgctta tgactactca attgcaaaaa taatggatga gtgtgatata aatggtattt
     1201 taataggaga ttcattagga atggtcataa aaggtgaaga aaacactcta tctgttacca
     1261 tagacgaaat tatatatcat acaaaagctg taaaaaatgg tgtaaaaaat gccttaatcg
     1321 taagtgatat gccttttcta tcttaccatg tttctataga agatgcagtt aaaaacgctg
     1381 gtagacttat aaaagaagga ggagctcatg ctgtaaagtt agaaggtggc tcaaacgtta
     1441 taaagcaaat agaaagcatt gtaaatgctc aaatacctgt aatggggcat ttaggattaa
     1501 ctcctcaatc agtaaattca tttggtgggt ttaaggttca aggaaatacc agtgaaacag
     1561 caagacaact tattgaagat gctaaattaa tagaaaaagc aggtgcattc tctattgtcc
     1621 ttgaaggagt gcctacgaaa atagctgaga tggtaactaa ttctatttca attcctacaa
     1681 taggtatagg ggcaggaatt aactgtgatg gacaaatttt agtttatcaa gatatgttgg
     1741 gaatgtttgg agattttgtt cctaagtttg taaagcagta tgcaaatata ggagatataa
     1801 tgaaagattc aattaaaaat tacatcctag aagttaatac aggtgcattt ccacaagaaa
     1861 aacacagctt ttcaataaat gaatctgagt tagaaaaatt atactaatat taaggatggt
     1921 acaaaatgct tgtaaaagaa attaaattac taagaaatat aatcaaagat tggagaaaac
     1981 atggctattc tataggcctt gttacaacaa tgggattttt acatgaagga caccaaagtc
     2041 ttataaaaaa agctataaaa gaaaatgata aagtagtagt gagtgtattt gtaaatccaa
     2101 ctcaatttgg accaaatgaa gattttaata gctatccaag agatatagat aaagatttta
     2161 aatattgtat ggatagtgga gcaacagtag tctttaaccc atcaccagaa gaaatgtatt
     2221 taaaaggtaa ttgtactacc attaatgttt ctggacttac agattttctt tgtggagcta
     2281 aaagacctgt tcattttgga ggtgtctgcc tagttgtttc aaagtttcta aatatagtaa
     2341 cacctgataa agcttatttc ggagagaagg atgcccaaca attagctgta attaaaagaa
     2401 tggtcaagga tttaaacata gatacagaaa taataggctg tcctataatt cgtgaaaatg
     2461 atggattagc aaaaagttcg agaaatacat atctctctga ggaagaacga aaatctgctc
     2521 taatattaaa taagagctta agtttagcaa aagaagaatt agtaaaaggc aatctaaatc
     2581 cagagaatat aaaagaatta ataatagcta aaataaattc tgaacactta gcaaaaatag
     2641 actatgttga aattgtagat agtgagacat tacaacctgt taagcaaata gaacattcta
     2701 tacttgtggc aattgctgtg tttataggaa aaaccagact aattgataat tttacatttg
     2761 agttaaatat atagtctata attttatata atatatctaa aaaataatag aatacctaaa
     2821 aagtaataaa ttacctaaaa aataataaat tgctta
//
LOCUS       DAMKNB010000179         2793 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.185, whole genome shotgun sequence.
ACCESSION   DAMKNB010000179 DAMKNB010000000
VERSION     DAMKNB010000179.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2793)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2793)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2793
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.185"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            complement(<1..254)
                     /locus_tag="PC494_003629"
     CDS             complement(<1..254)
                     /locus_tag="PC494_003629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF3914078.1"
                     /translation="MSGIISVMTQSLILSIMALGVYITYKILDFPDMSADGSYTMGAS
                     IVAFSLTNGISPVVATLMAILCGCTAGLVTGILHIKFKIS"
     gene            complement(1063..2100)
                     /locus_tag="PC494_003630"
     CDS             complement(1063..2100)
                     /locus_tag="PC494_003630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDF3914079.1"
                     /translation="MIKSKKILSLIIAGVLGVSMLTGCSQNDGSNASNENKETDSKKQ
                     KNIGITQLVEHPSLDKAKKGFIKALEDKGYKDGDNIKIDFQNAQNDMPTTQSIASKFV
                     SDKKDLIYAISTPSAQAAYNATKDIPIIMTAVTDPVEAGLVKSLEKPGGNVSGTSDYL
                     SIDKTLELVKTLTPKAKKIGVIYNTSEVNSKIQVDSLHDYAKKNNYEVVEKGISSSSE
                     VNQAISSLVGKIDVLYVPTDNLIVSSMPIVSKVANENKIPIIASEEGSVSSGALACCG
                     IDYEKLGYKAGELAIEVLEGKSVGDIPVTTLDETEIIINEDTLKALDMQKLSADNIKY
                     IKSDENAKSAK"
     gene            complement(2197..>2793)
                     /locus_tag="PC494_003631"
     CDS             complement(2197..>2793)
                     /locus_tag="PC494_003631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003399531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDF3914080.1"
                     /translation="GLIKESSGQITLDSTTITNLAEYKRTQIVSRVFQDPSLGTCPSM
                     TVRENLSLALNKGKLLNLKKCLRHKTNDLEHLLEGISLDLKKYLDIKVQYLSGGQRQS
                     LSLIMSSLASPKVLLLDEHTAALDPKTSNEVIELTDKIVREKNITTLMVTHNLKHALQ
                     YGDRLIMLHKGEVVLDVKDKEKEDLTVEEILEKFEYAV"
BASE COUNT          937 a          431 c          364 g         1061 t
ORIGIN      
        1 ttagatatct taaacttaat gtgaagaatc cctgtaacaa gaccagcagt acaaccacat
       61 aagatagcca ttaaagttgc tactacagga gaaataccat tagtaagaga aaatgctaca
      121 atagaagcac ccattgtgta gctaccatca gcagacatat ctggaaaatc taagattttg
      181 taagttatat aaacccccag tgccataatc gataaaatta aactttgcgt cattacagat
      241 ataatacctg acataaataa aacactcctt tgaaaatatt tttataattt taattatttg
      301 ctaattttgt gtataaaaaa accacatagt gtacaaaact atgtggtaaa aacacgaata
      361 agccacatag tttaatctat gtggctctta tatagttaaa tgaaaacttt ataaacaata
      421 tagccaacat agatacaatc ccaaaatttt agtagtctta aggggtctgt atctatgtta
      481 aaacgtaggt acaaacccta aaaatagtgg ctataataat aataatattt tctattgttt
      541 aataaagtat tcataattat ctctcccttt taatatttta attagtcaga aaattatatg
      601 tattctcgac ttgttataaa ttataaatta tacaataata aaagtcaact gctaaattta
      661 attaaaatac taaataatgt atactcagaa tacttttaaa ttaatgtatt gtttgcaaaa
      721 aacgttatcc taagttataa gtgaatgtgg aaattttatc aaaatattta ctagatatgg
      781 aataactaga catgtatatc aatcaaatat cataaaaaaa agctgtctgg agaatattaa
      841 aattcttttg gacagctcaa gtagtgatta gaaagttata taactttcat aatcagtcgt
      901 caatatagac gacttttatg gaaaatgaat aactttatat gcaatattca aattgctaca
      961 ataagcacaa ttttcaaagg gttagggtgg ataagagtac ttattatata aagttttcat
     1021 attacctact tcatattacc tattttttga aattaatagg ttttattttg cagattttgc
     1081 attttcatct gactttatat actttatatt atctgctgat aacttttgca tgtcaagtgc
     1141 ttttagtgta tcttcgttaa ttattatttc agtttcatct aatgtagtaa ctggtatatc
     1201 gccaacagat tttccttcta atacttcaat agcaagttct ccagccttat aacctagttt
     1261 ttcataatct attccacaac aagctaaagc accagaagac acagaacctt cttcagaggc
     1321 tattatagga atcttgtttt cattagcaac tttagaaact attggcatag aagaaactat
     1381 taaattgtca gtagggacat ataaaacatc tattttgcca actaaactag aaatagcttg
     1441 gttaacttca cttgaagagc tgattccttt ttcaactact tcataattat ttttcttagc
     1501 ataatcatgt agagaatcaa cttggatttt tgaattaact tcactagtat tgtatataac
     1561 ccctattttc tttgcttttg gagtcaatgt tttaaccaat tctaatgttt tatcaattga
     1621 aagataatca gatgtaccag aaacatttcc acctggtttt tcaagagatt taacaagtcc
     1681 agcttctaca gggtctgtaa cagcagtcat tattatcgga atatctttag tagcattata
     1741 agctgcttgt gcagatggag tagatatagc atatatcaaa tcttttttgt cggatacaaa
     1801 cttactagca atactttgtg tagtaggcat atcattttgt gcattttgga aatctatttt
     1861 tatattatct ccatctttat agcctttatc ttcgagtgct ttgatgaatc ctttctttgc
     1921 tttatccaga gatggatgtt ccactaattg agtaatacct atattttttt gttttttgct
     1981 atctgtttct ttattttcat ttgaagcatt ggagccatca ttttgagaac atccagtaag
     2041 cattgataca ccaagtactc ctgctataat taaacttaat atttttttac tttttatcat
     2101 tttattttcc tcccttaaaa tttattaatt atatttgttc atatattcat atgatagatt
     2161 ataaatattt ctgattaaaa ctaagatttt aatttcttat actgcatatt caaatttttc
     2221 taagatttct tcaactgtta aatcttcttt ttctttatct tttacatcta atacaacttc
     2281 acccttatga agcattatca acctatctcc atattgaaga gcgtgtttca agttgtgagt
     2341 aaccataagt gtagttatat ttttctctct tacgatttta tctgttaact ctattacttc
     2401 atttgatgtt tttgggtcaa gtgctgctgt atgttcgtct agtaataaga ccttaggact
     2461 tgctaagcta gacataatta gtgatagtga ttgtctttga ccccctgaaa gatattgtac
     2521 tttaatatct aaatattttt ttaaatccaa agaaattcct tcaagtaagt gttccaagtc
     2581 attcgtttta tgacgaagac atttttttaa gttcaataat ttccctttat taagtgctag
     2641 agataaattt tctctaaccg tcatagaagg acaagttcca aggcttgggt cttgaaaaac
     2701 tctacttact atttgagttc ttttatactc agctaaattt gttatagtag tactatctaa
     2761 agtaatttga ccagaagatt cttttataag ccc
//
LOCUS       DAMKNB010000180         2730 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.186, whole genome shotgun sequence.
ACCESSION   DAMKNB010000180 DAMKNB010000000
VERSION     DAMKNB010000180.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2730)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2730)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2730
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.186"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            231..383
                     /locus_tag="PC494_003632"
     CDS             231..383
                     /locus_tag="PC494_003632"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3914081.1"
                     /translation="MGSVSNRSGVYKISMVRMFHKGLTKQRMYGSKFVLCRNAKVREI
                     VAGVAK"
     gene            712..2622
                     /gene="ltrA"
                     /locus_tag="PC494_003633"
     CDS             712..2622
                     /gene="ltrA"
                     /locus_tag="PC494_003633"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HDF3914082.1"
                     /translation="MPKNKNETLCVEDLRHAEYYEMQNTFDDLYAKSKNGDIFTHLMD
                     IILSRENILLAYRNIKANAGSKTAGTDGTIIKDIGKLPAETVVKKVRYIVAGTPHGYR
                     PKPVRRKEIPKPNGKTRPLGIPCMWDRLIQQCIKQVLEPICEAKFSENSYGFRPNRSV
                     ENAIKATYNRLQISQLHYVIEFDIKGFFDNVNHSKLIKQIWAMGIRDKHLIFILKRIL
                     KAPIKMPDGTITYPEKGTPQGGIISPLLANIVLNELDHWVESQWHENPVTKNYVVHIN
                     KSGSPCKSNAYKEMKKTKLKEMYMVRYADDFRVFCRYKESAEKTKIAITQWIEQRLKL
                     EVSQEKTRIVNVRKRYSDFLGFKIKMIPRRKKLVVKSHISDKQFKTQKDKLVSQAKKI
                     ASPSKGKTELEEIRLYNSMVLGMQNYYQIATNVNLDCMKLNRAVMAIFTNRLGASKKG
                     RLRKTGRQLTTKEATRYGKSKMLRYVAGEGEPIFPVGYIQHRKPMAKVYSANCYTPEG
                     RKFIHTNLSVDKLLMYQLMKLSLENRTIEYADNRISLFSAQHGKCAITLEEFQQANEI
                     HCHHIVPTRAGGNDDYKNLILVKEAVHRLIHAKTEETIQKYIALLKLNKVQLIRLNKY
                     RVLAGNQELNLI"
BASE COUNT         1064 a          435 c          553 g          678 t
ORIGIN      
        1 cgttccttag tgaaaagcta aggcactaat aaaagaacga aaaagtttga ttattaggag
       61 aactgataat ctgacaggtg gaatgatgaa gtaacgctct gaaacgcctg ccctgagcct
      121 ccgacaagca ttgaatgagg aaactcagaa tgtttgaagc tcggtaaaga cggctgaaag
      181 ataccgtaat agttgatgaa catatatctt ctatcgaaaa ctatccagag gtgggtagcg
      241 tatccaacag gtcgggggtc tataaaatat ctatggttag aatgttccac aagggactga
      301 cgaaacagcg aatgtacggg tctaaatttg tactttgtag aaatgcaaag gtacgagaaa
      361 tcgtagctgg tgtggcaaag taagaatata ggttatgaaa tgccatatac cgttacaggc
      421 ggtatcaagc cagcaggctt atagctagtg acctaaggat atatatgtat agataagatt
      481 atcggaacga ggaaaggtat tgggttctca tcaagagaat aagctgacga agaacaataa
      541 gcagttgaac caatgctgaa aagcagaggg cgaacctaag aaattcttgt aatgagaatg
      601 gaggaatacc ctcaagtcgt gtatatatta gaaaagtatt atgttgtttt aataaggatt
      661 acgagtaaga taaaaaagct cactcaattt caagcaaagg agtgaagcct tatgcctaaa
      721 aataaaaatg aaacattgtg tgtagaagat ttaagacacg ctgaatatta cgaaatgcaa
      781 aacacctttg atgatttata tgccaaaagt aagaatggag atattttcac tcatcttatg
      841 gatattatcc tatcgagaga aaatatatta ctggcatatc gaaatatcaa agcaaatgca
      901 ggcagtaaga cagcaggaac agacggtaca ataattaaag atattggcaa attgccagca
      961 gaaacagttg tcaaaaaggt aagatatatt gtcgcaggca ctccacacgg gtatcgacct
     1021 aagccagtaa ggcgaaaaga aataccaaaa ccaaatggga aaaccagacc tctaggcatt
     1081 ccttgtatgt gggacaggct tatacaacaa tgtatcaaac aagtattaga accaatctgc
     1141 gaagctaaat ttagtgaaaa cagctacggt ttcagaccta ataggtcggt tgaaaatgca
     1201 ataaaagcaa cctataaccg cctacaaatc agccagctac attatgtgat tgaatttgat
     1261 attaagggtt tctttgacaa cgtgaaccat tccaaactga taaaacagat atgggctatg
     1321 ggaatacggg acaagcactt gatattcatt ttaaaaagga tattaaaagc tccaattaaa
     1381 atgcctgacg gcacaataac atatccagag aaaggaactc cacagggggg aattatatcc
     1441 ccactactag ccaacattgt tcttaatgag ttagaccatt gggtagaaag tcaatggcat
     1501 gaaaatcctg ttacaaaaaa ctatgtggtt catatcaata aaagcggtag cccatgtaaa
     1561 agcaacgctt acaaagaaat gaagaaaaca aagttaaagg aaatgtatat ggttcgttat
     1621 gcagatgatt ttagagtttt ctgtcgctac aaagaaagtg ctgaaaaaac caaaatagca
     1681 attactcaat ggatcgagca acgactaaaa ttggaagtat cacaagaaaa aacaagaatt
     1741 gtaaatgtta gaaaaagata ctccgacttt cttggtttca agattaaaat gataccgaga
     1801 agaaagaagt tagttgttaa atcacatata agtgataaac aattcaagac ccaaaaagac
     1861 aagctggtat cacaggcaaa gaaaattgct tctccctcaa agggaaaaac agaattagag
     1921 gaaataagac tttataattc aatggtatta ggtatgcaaa attattatca gattgcaaca
     1981 aatgtaaatc tggattgtat gaaacttaat agagctgtaa tggctatctt cactaacaga
     2041 ttaggtgcaa gcaaaaaggg cagattgaga aaaacaggca gacaacttac aacaaaagaa
     2101 gcaacaagat atggtaaatc taaaatgctt cgatatgttg ctggcgaggg cgaacctata
     2161 ttccctgttg gatatatcca acacagaaaa ccaatggcaa aagtgtattc agcaaactgc
     2221 tatactccag agggaagaaa atttatccat accaatctaa gtgttgataa attactgatg
     2281 tatcagttga tgaaattatc tttggaaaat cgcacaatag aatacgcaga caatcgaatt
     2341 tcgctatttt ctgcccaaca tggaaaatgt gctataactc tggaagaatt tcaacaagct
     2401 aatgaaatac actgtcatca tattgtacca actagggctg gtggtaatga cgattataaa
     2461 aatcttattt tggtaaaaga ggcggtacat cgtctaatac acgcaaaaac agaagaaaca
     2521 atacaaaaat atatagctct attgaaacta aataaagtcc agctcataag actaaataaa
     2581 tatagagtat tagctggcaa tcaagaatta aacttgatat aggtctacta cataaatact
     2641 tttcaatata aacacgatgg aacgcggagt gcggtgaaag tcgcacgctc cgtgtgaatg
     2701 gggggaaaag tttgagatat ttataatatc
//
LOCUS       DAMKNB010000181         2644 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.187, whole genome shotgun sequence.
ACCESSION   DAMKNB010000181 DAMKNB010000000
VERSION     DAMKNB010000181.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2644)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2644)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2644
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.187"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            490..969
                     /locus_tag="PC494_003634"
     CDS             490..969
                     /locus_tag="PC494_003634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HDF3914083.1"
                     /translation="MDKTTFTNNILESEQTLYRVSKSILGNDQDCEDAVNNAILKAYE
                     KLDSLKEEQYFKTWLIRIVINECNSLRRKRLKSLSFEDVFKNKKIDEKDDYSDLYTAI
                     QSLPKKIKIPIVLYYIEGYSVDEVKEILDIPQGTVKSRLSRGRRLLKTKLENTEVII"
     gene            966..1745
                     /locus_tag="PC494_003635"
     CDS             966..1745
                     /locus_tag="PC494_003635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3914084.1"
                     /translation="MNKNILNNSFPEVPESFHNSLSKTLNSLPEREENYKMINNKTHK
                     LPFRKGLVATLAITLILSTTALAVGHIYSLVGKSSTKATYTSIPTTEQVKKDFNFTPN
                     IVSEFSNGYKFKGAYTVNKKAFDKENNVLGKSKALSFEYKNGNDEISLDTANNVLGKS
                     SDNLKVVDTYKDINISYEAFAQKFVPEGYKMTEQDKIDEKSGKYTFSVGPNNESDKVE
                     VNKFKFLTWKQDEVYYSFTVQDSNLSMNDLVKMAHEVIDAK"
     gene            complement(1995..2495)
                     /locus_tag="PC494_003636"
     CDS             complement(1995..2495)
                     /locus_tag="PC494_003636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDF3914085.1"
                     /translation="MIEGIKFIKAEEKYIYSYWQTFDKIAKERKYLAMDEAFPFEETV
                     EFIKNIINKNLPQLFIIDLESDNCIGWCDVLPKTEKVGYLGMGILKEYREKGIGSNLL
                     KQIIDLSKEYGYEKIELDVFKSNSRAIHVYKSLGFVEVNTISSGFTWNDRPVKEEVIQ
                     MELTLI"
BASE COUNT         1031 a          359 c          320 g          934 t
ORIGIN      
        1 ttatattttt taagtttatt tatgttcatc tctatctaaa ataatgacat ttctaactct
       61 taattctcat ttaagtttca ttgttttttc ttaaaagcct acttttagtc aagatactgt
      121 tatctttact cattatttaa agaacttatt ttaaatctgt acatgaagta aataatccaa
      181 aagcattgtt attctaacta ctcaacatta aatacttact attttctaat tactcaatat
      241 aaacacttac tataaaacta aatatataaa tggcttctaa agtttaatat atctacatgg
      301 ctttatatat gatgggaaaa tactagaaaa aaatatatta tagaatattt gtatagaata
      361 ggcaaaactt tcaaacttaa atttatcaaa taatcataaa aaaagtgaac catctatagt
      421 aaaattttat ctaataagtg aaaggcaaaa aagtagcgct acgatttgca tagaagggaa
      481 ggaacttagt tggataaaac tacatttaca aacaatatac ttgaatcaga acagactttg
      541 tatcgagtat ctaagtctat tctaggaaac gaccaagact gtgaagatgc cgtcaacaat
      601 gctattttaa aagcatatga aaagttggat tctcttaagg aagaacaata ctttaaaaca
      661 tggctgatta gaatagtcat aaatgaatgt aattcattaa gacgcaaacg attaaaatct
      721 ctatcatttg aagatgtctt caaaaacaaa aaaattgatg aaaaagatga ctatagcgat
      781 ttgtatactg ctattcaaag tctacctaaa aaaattaaaa ttccaatagt cctttactat
      841 attgaaggtt attcagtaga tgaagttaag gaaatattag atatacctca aggaactgta
      901 aaaagtagat tatcaagagg aagaagatta ttaaaaacta aattagaaaa cacggaggta
      961 atcatatgaa taaaaatata ttaaataatt cgtttccaga agttccagaa agttttcata
     1021 atagtttaag caaaacacta aatagtttac cagaaagaga ggaaaattat aaaatgatta
     1081 ataataaaac acacaaatta ccatttagaa aaggcttagt tgcaacttta gccattactt
     1141 tgatattgag cacaacagcc cttgcagtag gacatatata tagtttggtt ggaaaatcaa
     1201 gtactaaggc tacctataca tctatcccaa ctacagaaca agtaaaaaaa gactttaact
     1261 ttacccctaa tatagtttct gaatttagta atggatataa atttaaagga gcatatactg
     1321 taaataaaaa agcatttgac aaagaaaata atgttttagg aaaatcaaaa gcacttagtt
     1381 ttgaatataa aaatggcaat gatgaaatat ctcttgacac agcaaataat gtacttggga
     1441 agagttctga caatctaaaa gttgtagata cttacaaaga tattaatatt tcttatgaag
     1501 cattcgcaca aaagtttgta ccagaaggtt ataaaatgac agaacaggat aaaattgatg
     1561 aaaaatcagg caaatacaca tttagtgtag ggccaaataa tgaatcagac aaagttgaag
     1621 ttaataaatt taagtttttg acatggaaac aagatgaagt ttactattct tttacagttc
     1681 aagactcaaa tttatctatg aatgacttag ttaaaatggc tcatgaagta atagatgcaa
     1741 aataaacata agtaataata agttgtttat gagtttatta tttatgactt taattttttt
     1801 attagtaaac atggttgtat cttccatctt tatattttct ttaaatttaa tatataaaat
     1861 tttagatatt tagctacctt caaaagaacc attattaaaa agcccttaaa aatatttctt
     1921 ttatatggaa ttttaagggc tttaacttta ttttatacaa gtgtatatgg aattttaaag
     1981 actttaactt tattttatat aagtgtaagc tccatttgaa ttacttcttc ttttacaggt
     2041 ctatcattcc atgtaaaacc actagatatt gtatttacct ctacaaaccc taaagattta
     2101 taaacatgaa tagctctact attactttta aatacatcaa gctcaatttt ttcataccca
     2161 tattcttttg ataaatcaat aatttgtttt aaaagattac ttccgatacc tttttcccta
     2221 tactctttaa gaatacccat gcctaaataa ccaacttttt cagttttagg taaaacgtca
     2281 caccaaccaa tacagttatc tgattctaaa tcaattataa acagttgtgg taagttttta
     2341 tttataatat tttttataaa ttcaactgtt tcttcaaaag gaaaggcttc atccatagct
     2401 agatatttcc tctcttttgc tattttatca aaagtttgcc aatacgaata aatatacttt
     2461 tcttctgcct ttataaattt tatgccttct atcaacttaa catttcccct ttttaatttg
     2521 tgattgtagt taacttattt tatatgattc tagtttataa tgctatataa attactatat
     2581 attagcttaa aatatctttg tatatttcta taaaattaaa accaatatat ctatctcttg
     2641 tatc
//
LOCUS       DAMKNB010000182         2587 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.188, whole genome shotgun sequence.
ACCESSION   DAMKNB010000182 DAMKNB010000000
VERSION     DAMKNB010000182.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2587)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2587)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2587
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.188"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            complement(226..1476)
                     /locus_tag="PC494_003637"
     CDS             complement(226..1476)
                     /locus_tag="PC494_003637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1015 domain-containing protein"
                     /protein_id="HDF3914086.1"
                     /translation="MATIKPFKAIRPNKYIVDKVAALPYDVMNSKEARRIAEGNPYSF
                     LHIDKSEIDLDENIDLYDEKVYLKARENLDEFRKQEILVKDDKECIYIYKQIMDGRAQ
                     VGIVACISVDESLNGTIKKHEYTRPEKEIDRTKHIKYCDANTGTILVTYKHQRVIDDI
                     INDFMDNNEPLYDFITDDKIEHTVWKIDNDDIIDNLVDKFEKLDYLYIADGHHRTASA
                     ENVAKEMRAKNPNYTGKEEFNYFIAMIAPDENLMVLDYNRVIKDLNGLSEEEFINKIK
                     ENFELEEIEGKEKYKPDKKGTFGMYLGDKWYKMKANKNLLEIEDPVDSLDISILQDYV
                     IDAILGIDNPRVDKRIDFIGGIRGLEELEKRVNEDMKVAFAMYPTSIEDLIRVADANK
                     IMPAKSTWFEPKVRCGLFLHEINE"
     gene            complement(1508..2449)
                     /locus_tag="PC494_003638"
     CDS             complement(1508..2449)
                     /locus_tag="PC494_003638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-3-phosphoglycerate dehydrogenase"
                     /protein_id="HDF3914087.1"
                     /translation="MYNILVTDGIEKEAARKLRELDFNVIEQFYEKDVLGDKLKDVDV
                     LVVRSATKVTKDVIDKALEGKKLKLIVRGGVGLDNIDVKYAQANGIKVMNTPNASSIS
                     VAELTIGQLFVLARFINTANVTMRDGKWEKKKYKGTEINGKTLGLIGFGRIAKEVAKR
                     AELLGMNVIYTDIMGEAQGFNNYKFCDMEEVLENADFLSLHIPFDKNKGAVITEKEIN
                     KMKKGAYLINCARGGLVDEKDLLKALDEGKLSAAAIDVYEQEPTLNLDLVNHPRVSPT
                     PHIGASTVEAQERIGDEIVNVIQDFFLDFNNLIGVAL"
BASE COUNT          779 a          497 c          242 g         1069 t
ORIGIN      
        1 aatacacatt taaaacctta taaatataca aatacaatta tatgaatttt catcctcaat
       61 tatagcatag aatatgacta tctatatcct aaaattatcc atttctaaaa aaaaggtaac
      121 tattattaag aatatcaact tatagaattt atattccaca tacgattttc aatcaaaaaa
      181 acaagggcta aaaagtgaat tgtgcacttt ttagcccttt attaattatt catttatttc
      241 atgtaagaat agaccacatc ttactttagg ttcaaaccat gttgacttag ctggcattat
      301 cttatttgca tctgctactc ttattaaatc ttcaatacta gtaggataca ttgcaaatgc
      361 tactttcata tcttcattaa ctcttttttc taattcttca agacctctaa ttccaccgat
      421 aaaatcaatt cttttatcta ctctaggatt atcaattcct aaaatagcat caataacata
      481 gtcttgtaat atagaaatgt ctaatgagtc aacagggtct tctatttcta ataaattttt
      541 atttgctttc attttatacc acttatcacc taggtacatt ccgaaagttc cttttttgtc
      601 aggtttatat ttttcttttc cttctatttc ttctagttca aaattttctt ttattttatt
      661 tataaattct tcctcgctta aaccatttaa gtctttgata accctattat aatccaaaac
      721 cattaaattc tcatctggtg caatcattgc tatgaagtaa ttaaattctt cttttccagt
      781 ataatttgga tttttagctc tcatttcttt ggctacattt tctgctgaag ctgtcctatg
      841 atgaccatct gcaatgtata gataatctaa tttttcaaat ttatctacta ggttatctat
      901 tatatcatca ttatcaatct tccatactgt atgctctatc ttgtcatctg ttatgaaatc
      961 atataaaggt tcattattat ccataaaatc attgattata tcatctatca ccctttgatg
     1021 tttgtaagtt acaagtatag ttcccgtatt agcatcacag tattttatgt gtttagttct
     1081 atcaatttcc ttttctggtc gagtgtactc atgttttttt attgttccat tcaagctttc
     1141 atcaactgat atacatgcta ctataccaac ttgagctcta ccatccatga tttgtttata
     1201 tatatatata cactctttgt catcttttac tagaatttct tgttttcgaa actcatctaa
     1261 attttctcgc gcttttaaat aaactttttc atcatataaa tctatatttt catctaaatc
     1321 aatttctgat ttatctatat gcaaaaatga atatggattc ccttctgcaa ttcttctagc
     1381 ttctttacta ttcataacat cgtaaggaag tgctgctact ttatctacta tatatttatt
     1441 tggtctaatc gccttaaatg gtttaatcgt tgccattact aatttcctcc taattataca
     1501 aaatatttta taatgctacc cctattagat tgttgaagtc aagaaagaaa tcttgaatca
     1561 catttactat ttcgtctcct attctttctt gagcttctac tgtagatgcc ccaatatgag
     1621 gtgtaggaga aactcttgga tgatttacta agtctaaatt taatgtaggt tcttgttcat
     1681 aaacatctat agcagctgct gataatttac cttcatctaa tgcttttagt aaatcttttt
     1741 catcaactaa accgcctctt gcacagttta ttaaataagc ccctttcttc atcttattta
     1801 tttctttttc agttattact gcccccttat tcttatcaaa tggtatgtgt aaagataaga
     1861 aatctgcatt ttctaaaact tcttccatat cacagaattt ataattgtta aagccttgcg
     1921 cctcacccat tatgtcagta tatataacat tcatacctaa taattctgct ctctttgcaa
     1981 cttcttttgc aattcttcca aaacctataa gtccaagtgt ctttccatta atttctgtac
     2041 ctttatactt tttcttctcc cattttccat ctctcatagt tacatttgca gtatttatga
     2101 atcttgcaag aacaaataat tgacctattg taagctctgc aacagatata ctgcttgcat
     2161 ttggagtatt cataactttt atgccattag cttgagcata tttaacatct atattatcca
     2221 gacctactcc acctcttact atcaacttca actttttacc ctctaatgct ttatctatta
     2281 catctttagt aactttagta gctgaacgta ctacaagtac atcaacatct ttaagtttat
     2341 ctcctaaaac atctttttca taaaactgct ctatcacatt aaaatctaac tctctcaatt
     2401 ttctcgctgc ttctttctct attccatcag taactaatat attatacata acaaactcct
     2461 ccaattttta ttcacttaat ttttccaatt tttatttttt aaagtatttt catcaataaa
     2521 aaactttact taattcaact ttctgtttat ataattttca aaatattttt ttattaaagt
     2581 catgtca
//
LOCUS       DAMKNB010000183         2474 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.189, whole genome shotgun sequence.
ACCESSION   DAMKNB010000183 DAMKNB010000000
VERSION     DAMKNB010000183.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2474)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2474)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2474
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.189"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            complement(235..990)
                     /locus_tag="PC494_003639"
     CDS             complement(235..990)
                     /locus_tag="PC494_003639"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HDF3914088.1"
                     /translation="MLKVIISGYNGTMGRVLAECVKKDNELELVCGVARSADEKGHHS
                     DTKLYKTMTDVAEKTDVIIDFSHHETLEPILSYALKNNTPVVLATTGYDENDLNKIEE
                     ASKNIPILLSSNTSLGVNILIKLVKDASKMLEGFDIEIIEKHHNRKEDAPSGTATMIA
                     NAIREVLPESENTHGRYGRDCKRKSNEIGIHSIRGGNIISDHDVVFAGDNEVLTLSHH
                     SQSDEVFANGSIVAAKFLIGKQSGLYKMSDILG"
     gene            1430..2419
                     /locus_tag="PC494_003640"
     CDS             1430..2419
                     /locus_tag="PC494_003640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HDF3914089.1"
                     /translation="MLKEEKTYQEKDAKVFNGVAALIMILLFLVVSIGIMVFGIVKLD
                     SGFTGIGSLMLILGLVFIVVDFILFFGLKMINPKEAIVLVLFGNYYGTIKKEGYYWVN
                     PFCSAINPAVSRINVSKSSSDEKVDISTNSSGKKVSLKTMTLNNEKQKVNDLLGNPII
                     IGVVVIWKVIDATKAVFNVDNYNTFLSIQCDSTIRNVSRLYPYDVSEDGDEKSLRGSS
                     QEIADRLKDELQSRVDIAGIEVCEVRITHLSYAPEIAAAMLQRQQAEAIIAARKKIVE
                     GAVSMVEMALTNLSENNVVTLDEERKAAMVSNLLVVLCGNKDAQPVVNSSSIY"
BASE COUNT          912 a          314 c          364 g          884 t
ORIGIN      
        1 catataccaa taaataggat aatatttaat aggtttatat gatgaagaga ttataaaata
       61 ataaacaata taattccata taccaataaa taagataatc tttaagaaaa atgattatat
      121 ttaaaaggta aacataaaat ttataaactt ttagaataga aatctcaatc aattagatat
      181 tcaaattgat gaatatgaat acctaaatag attgagattt attatgtaca aaacttatcc
      241 taatatatct gacattttat aaagcccaga ttgcttacca attaaaaatt tagctgcaac
      301 tatagaaccg tttgcaaata cttcatcaga ttgagaatga tggcttaatg taagaacttc
      361 attatcacct gcaaatacaa catcatggtc gctgattata ttgccacctc ttatagagtg
      421 tattccaatt tcatttgatt ttcttttaca atctctacca tatctaccat gtgtattttc
      481 actttcaggc aagacttctc taattgcatt agctatcata gtagcagttc cactaggggc
      541 atcttctttt ctattgtgat gtttttctat gatttcaata tcaaaacctt ctaacatctt
      601 tgaagcatcc ttaactaatt ttattaatat attcactcca agagatgtat ttgatgataa
      661 taatatagga atgttttttg atgcttcttc tattttattt aagtcatttt catcatatcc
      721 agtagtagct aatactacag gtgtattatt ttttagagca tatgacaata ttggctctaa
      781 agtctcatga tgtgaaaagt ctataattac atcagttttt tcagctacat cagtcattgt
      841 tttgtaaagc tttgtatcac tatgatgacc tttttcatca gcagacctag ctacaccaca
      901 aaccaactct aattcattat ctttttttac acattctgct aaaactcttc ccattgttcc
      961 attatagcca ctaattataa ctttcaacat aaattcctcc tatgaaatta ataaaaattt
     1021 gttatatttc tataagttta ttttatcact aatataattt atataaaata atattagtga
     1081 taataagctt acaatttatc ttacattaaa aaatttaagt ggatttttca aaatatagat
     1141 aaatttcttt ttcattgtat aaatgataaa aatatatttg acttcatacc aaaaagagtg
     1201 ccccatgaac taaaaagtta attttgaaat accatattca tatatcatat gatttatttg
     1261 gaaatcaata ttaatacatt aaaataacta aatacatgta tgcataaaga tgtataaaaa
     1321 atatataaac atatagtatt aattttaaat tcaacaattt aattgttaaa agtgttatta
     1381 ttaaattaga aatatcttaa cttaatatac tgagatggga gtgatagata tgttaaaaga
     1441 agaaaaaact tatcaagaga aagacgcaaa agtattcaat ggagtggcag ctttgataat
     1501 gattttatta tttttagtag tttcaatagg tatcatggtt tttgggatag taaaacttga
     1561 tagtggattt actggaatag gttcacttat gttaattttg ggacttgtat ttatagtagt
     1621 agattttatc ctattttttg ggctaaaaat gattaatcct aaagaagcta tagttctagt
     1681 tttgtttggt aactattatg gaactataaa aaaagaaggg tactattggg tgaatccatt
     1741 ttgttcagca ataaacccag cagtatcaag aattaatgta tcgaaatctt catctgatga
     1801 aaaggtagat atatcaacta attcaagtgg caaaaaagta tctttaaaaa caatgactct
     1861 taacaatgaa aagcagaaag tcaatgattt attgggaaat ccaattataa taggagtggt
     1921 tgtaatttgg aaggttatag atgcaacaaa ggcagtattt aatgtggata attataatac
     1981 attcttatct attcagtgtg attctactat tcgcaatgtt tcaagacttt atccatatga
     2041 tgtatctgaa gatggagatg aaaaatctct tcgtggtagt agtcaggaaa tagcagatag
     2101 attaaaagat gaattacaat caagggttga tattgcagga attgaagtgt gtgaagtgag
     2161 aattactcat ctttcttatg caccagagat tgcagcagca atgttacaac gtcaacaagc
     2221 agaggctata atagcagcac gtaaaaagat tgttgagggg gctgtaagta tggtagagat
     2281 ggcattgact aatttaagtg aaaataatgt tgtgactttg gacgaagaac gtaaagcagc
     2341 tatggtaagt aatctgttag ttgtgctttg tggcaataaa gatgcacaac cagtagtaaa
     2401 cagcagttct atttattaaa ttataaaaag tttaatagtt tattttattg atatatagaa
     2461 aatttagtag ttca
//
LOCUS       DAMKNB010000184         2430 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.190, whole genome shotgun sequence.
ACCESSION   DAMKNB010000184 DAMKNB010000000
VERSION     DAMKNB010000184.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2430)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2430)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2430
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.190"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            322..1623
                     /locus_tag="PC494_003641"
     CDS             322..1623
                     /locus_tag="PC494_003641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HDF3914090.1"
                     /translation="MGKSKDVEIEKSILGTILLDNKLSYKLDELNENMFMNDICLEIF
                     KIMKELKKENIVIDVATVKSKIDRKSLAIKTSDVTNLITWGQNFGLDGHIKILKENLA
                     RRSINQNCQNLLHSLNLGENIDTCIYKFESNIKEILDKDTYENDDVNSIAGKVLDFLE
                     NKKDIGFKFGIKLLDTTIGGLFKGELTTIAAKSGVGKTALALQIMLNSFKQGKKTLFI
                     SREMTSEQVFMRNICRVTGVSTRNMKSKEIDENDWKLIVNAIGDLSENNLIYINDKID
                     TISAIRKRIRQVKPDLLIVDYVQLLTSQKSMDKREREVATFSRELKNMTLDFNIPVIQ
                     LSQLNDEMKDSRPYGDRPMRDSKAIYHDSNNVVYIHQLKGSDYEEAVRDIGESEEAVR
                     ASEYRGIKMVDLIVAKCRDGQTRHKHFCYFGDKLHFQELNY"
     gene            1699..1974
                     /locus_tag="PC494_003642"
     CDS             1699..1974
                     /locus_tag="PC494_003642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HDF3914091.1"
                     /translation="MLELRKIIELLEEHKIEVSIPKELHKYSLLEYLELCQQSGGTYF
                     YIKTLEGALKEARNELMIKLFNGKNYMELARMFEMSVINVRHIVRKK"
BASE COUNT         1002 a          196 c          473 g          759 t
ORIGIN      
        1 gagtaatgaa ttatattgaa cgatatatca ataattggca gtaagttata tcaaataaga
       61 tattactatc gagtaatgaa ttatattgaa caatatatta ataattggca gtaagttata
      121 tcaaataaga tattgctatt atgtagtaaa ttatataaaa caatgtatca gaataaatag
      181 tatattaata atttgtagta tatcatgacg aataatacag tcataacaaa tagtgagtca
      241 taacaaataa tgtatttata attgataatg tatttaaaaa tcaaaatata aaaacttata
      301 aggaaagaga gattaattta tatgggtaaa tcaaaagatg ttgaaataga gaagtctatt
      361 ttaggcacaa ttcttttaga caataaatta agctataagc tagatgaatt aaatgaaaac
      421 atgtttatga atgatatatg tcttgagata tttaaaatta tgaaagaact taaaaaagaa
      481 aacatagtga ttgatgtggc cactgtgaaa tcaaagatag atagaaaatc tctagcaata
      541 aaaacgagtg atgtgactaa tctaattact tggggtcaga attttggtct tgatggtcat
      601 attaaaattt taaaagaaaa tttagctaga agaagcataa atcaaaactg ccaaaacctt
      661 ttacacagcc taaaccttgg agaaaatatc gatacttgta tttacaaatt tgaaagtaat
      721 ataaaggaga ttttggacaa ggatacttat gaaaatgatg atgtaaatag tatagcaggg
      781 aaggtgcttg attttttaga aaacaaaaaa gatattggat ttaaatttgg tataaaatta
      841 cttgatacca ctataggagg tctttttaaa ggagagctaa ccacaatagc agctaaatcg
      901 ggggttggga agactgcttt ggcacttcaa ataatgttaa attcatttaa gcaaggtaaa
      961 aaaactttat ttataagtag agaaatgacc agtgagcaag tatttatgag aaatatatgc
     1021 agagtaactg gtgtaagtac aaggaatatg aaatctaaag aaatagatga aaatgattgg
     1081 aaacttattg taaatgctat aggtgattta agcgaaaata acttaattta tatcaatgat
     1141 aagatagata caattagtgc aattagaaag aggataaggc aggtaaagcc agatttatta
     1201 atagtggatt atgtgcaact ccttacatct cagaaaagca tggataagag agaaagggaa
     1261 gtagctactt tttcgagaga acttaaaaat atgactttag attttaatat acctgtaatc
     1321 caattaagtc agttaaatga tgaaatgaaa gattcaagac cttatggaga tagacctatg
     1381 agggatagca aagccatcta ccacgatagc aacaatgtgg tttatataca tcaattaaag
     1441 gggagtgatt atgaagaagc agtgagagat attggagaaa gtgaggaggc agttagagca
     1501 tcagaataca ggggaattaa gatggttgat ttaatagttg cgaagtgtag agatggacag
     1561 actaggcata agcatttttg ttactttggg gataagttac attttcaaga actaaattat
     1621 taggtcaata aagtagtaat aacaagctta ttaaaagtcg ggaaatagca aatagattat
     1681 aaaatatgag gtgaaaatat gttggaatta agaaaaatta tagaattact tgaagaacac
     1741 aagatagaag taagtattcc aaaggagtta cataagtata gtttattgga ataccttgaa
     1801 ttgtgtcaac aaagtggggg aacatatttt tatattaaaa cactggaagg ggctttaaaa
     1861 gaggctagaa atgagcttat gattaaattg tttaatggga aaaattatat ggaattagcg
     1921 aggatgtttg aaatgagtgt tattaatgtc aggcatattg ttagaaaaaa atagatattt
     1981 ttggagaata caagtgtgat atacttctga aatagaagtt attatagttg aaataaaatt
     2041 gtggttaata aattaaagtt gtgtataagt ttaagattat agaggagtat aagtgtgatt
     2101 aacaacatga ttttgtgaat aaaattgagg atatatatga gttaaatgtg tgattaataa
     2161 ggtaaggttg tgtataagat tatgagtatt taaaaggagg ggctataatt aatagtgtag
     2221 agttgtgtgt ttgcttaaga ttatataata atttaataga ttaaactata ctaataaggt
     2281 aaaatcgtgt gtttagttaa agcttattat aaaatcttga tatgtgatta atgatgcaat
     2341 atgtgaataa agttaagatt ataatagatt taacctgtgg ctaatagaat aaaattgtga
     2401 ataaagttaa gattataata ggtttaacct
//
LOCUS       DAMKNB010000185         2411 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.191, whole genome shotgun sequence.
ACCESSION   DAMKNB010000185 DAMKNB010000000
VERSION     DAMKNB010000185.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2411)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2411)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2411
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.191"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            complement(131..1423)
                     /gene="brnQ"
                     /locus_tag="PC494_003643"
     CDS             complement(131..1423)
                     /gene="brnQ"
                     /locus_tag="PC494_003643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HDF3914092.1"
                     /translation="MGEKQINFKDVIVIGFALFAMFFGAGNLIFPPYLGVLSGSSWLV
                     AFIGFLFADGGLALLAVIAATKFNGDTSKMFSRAGKGLSIALGCAMVICIGPLLAIPR
                     TAATTYEMGILPTIGSGISPVIFSIVFFALVLVLTIRPSKVVDIVGSILTPALLIALA
                     VLIVKGIVSPLGEIRDSSLIQNVFAEGITQGYQTMDALAASVFASIIIMSVIAKGYTG
                     EKEKMKATISAGVIAVIGMALVYGGLCYLGATVSQQYGQDVQQTALIVAITAALLGTT
                     GKILLAIIVALACLTTAIGLSSAAGQYFSTLTDGKLKYEHIVIVVCVFSAIISNFGVS
                     TIIQFSSPILSMVYPATITLVILALFSNKIKNDNVFKCAAYMALLVSVLTVATSFGIK
                     IPLVNSLPFASLGFNWIVPVVIAGIIGNFIPSKSSKTA"
BASE COUNT          808 a          384 c          252 g          967 t
ORIGIN      
        1 tttttaaatt tatcaaatag gattaataat gttcttttat ctacaataat ttaataattc
       61 ttttaaatat aaaaaggaat tgcctatata atttaaaggc aattccataa ttatcaatta
      121 gtttttatta ttatgcagtt ttactgcttt tagatggaat aaagtttcct attattcctg
      181 ctattacaac tggaactatc cagttaaatc ctaatgaagc aaatggtaag ctattaacta
      241 gaggaatttt tataccaaaa cttgttgcaa ctgttaatac acttactaat aatgccatgt
      301 atgcagcaca tttgaacacg ttgtcatttt taattttatt actaaataat gctagtataa
      361 ctagagttat agttgctgga tataccatac ttagtatagg agaagagaat tgtattattg
      421 tacttactcc aaagtttgat atgattgcac taaatacaca aactactata actatatgct
      481 catactttaa ttttccatct gtaagtgttg agaaatattg accagctgct gaagaaagac
      541 ctatagctgt tgttaaacat gctaatgcaa ctataatagc caataaaatt ttacctgtag
      601 ttccaagtaa agctgctgtt attgcaacta ttaaagctgt ttgttgaaca tcttgtccat
      661 attgttgaga cacagttgct ccaagataac ataatccacc ataaactaat gccattccta
      721 ttactgcaat tacacctgca cttattgtgg ctttcatctt ttctttctca cctgtataac
      781 ctttagctat tactgacatg attataattg atgcaaatac actagctgcc aatgcatcca
      841 ttgtttgata accttgagtt ataccttctg caaatacatt ttgtattaaa gaactgtctc
      901 ttatttctcc taatggagat acgatacctt taactattaa tactgctaaa gctataagta
      961 aagctggagt taatattgac ccaactatat ctacaacttt tgatggtctt attgttaaaa
     1021 ccaatactag agcaaagaat actatagaga atattactgg gcttattcca gaacctattg
     1081 taggtaatat acccatttca taagttgttg ctgctgttct aggtattgct aaaagtggcc
     1141 ctatacagat taccattgca catcctaatg caatacttaa tcctttgcct gctcttgaga
     1201 acatcttcga tgtgtctcca ttgaacttag ttgctgctat aactgctaat aatgccaaac
     1261 caccatctgc aaaaaggaat cctatgaaag ctactagcca actacttcca gataaaactc
     1321 ctagatatgg agggaagatt aagttccctg caccaaaaaa cattgcaaat agtgcaaatc
     1381 caattacaat tacatcttta aaattgattt gtttctcacc catttaaagc acccccattt
     1441 gaattttact accttttact aaaaaataag tccaatctct taattaaatg aaaacctttt
     1501 gacgagattt tatttaatta tacatttttg acttaaattt gtcaattatg tttcataatt
     1561 tataaaatct tcacaatatt taatacaact ttcttaatta aacaaaatca acctgtatac
     1621 tttaaacata gttggttttt tgttttttct ctaatttttc ttgataaaat taactattcc
     1681 gaataattaa aatattaaga ttttttagat tattcgattt attattaagt tgtattgctt
     1741 tatatactgt atatatcact ctcctttttt acattcatat aatcttttta attcaattta
     1801 aattttaaat attttgtgtt tattatataa tctgaaaaaa aagcagtcaa tagcattttt
     1861 aattttttta attttcaaaa ttatgattct caaaaaatcg ttttcctttt atcataacac
     1921 ctatttacgt taattcttgt agtattttgt atttattttg ctaaattgac agttaacttt
     1981 attcaatttt tattctactt gcgtagattt acctcttgtt ttttactctt aaaaccattt
     2041 tttctgaaaa ttccttatta tgatttatca acttattttt cttcataaca attactctct
     2101 aacttccaac ttacttaaac tttgcagttg ctagtattca cgtttacata cttatatgtc
     2161 ataattaact aaaaattctt aatatatctc tcaatgaaaa caatttactc atttatttaa
     2221 tacatttata taatcatatg tcttaaattt tgttttatta ttttattatt gtcacaattt
     2281 tatttatatt atatttttgt aaaaatcatt taatatgtat acttaaattt ataaaattac
     2341 tctaaaattc ttttttaatc tctattattg ttaaaaaata aactatatat ttttttgata
     2401 ttttcttata c
//
LOCUS       DAMKNB010000186         2381 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.192, whole genome shotgun sequence.
ACCESSION   DAMKNB010000186 DAMKNB010000000
VERSION     DAMKNB010000186.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2381)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2381)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2381
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.192"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            229..369
                     /locus_tag="PC494_003644"
     CDS             229..369
                     /locus_tag="PC494_003644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3914093.1"
                     /translation="MEKSNTTVTKKEKIEDIGMKLEHLLSEDITFYELLLEILYKEKE
                     EN"
     gene            complement(366..737)
                     /locus_tag="PC494_003645"
     CDS             complement(366..737)
                     /locus_tag="PC494_003645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF3914094.1"
                     /translation="MESLGDRIANLRKELDINQKELATKVGITEASLSRYENNLREPK
                     SEIIVRLAKALETSTDYLLGVNDNTKISKEDKLIIENLSVSEKTKKLLEKIYSLEKED
                     REAIEKMIDNAYLKRFLKEEN"
     gene            1286..1543
                     /locus_tag="PC494_003646"
     CDS             1286..1543
                     /locus_tag="PC494_003646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3914095.1"
                     /translation="MIIIRSQDKTNLMQINQIKIDGSQVYAVFESKIDTVKIGDYENN
                     TRAIQVLDNIQNFIENGTKYDYITSNKVRYNVNKIFQMPAK"
     gene            complement(1653..2333)
                     /locus_tag="PC494_003647"
     CDS             complement(1653..2333)
                     /locus_tag="PC494_003647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HDF3914096.1"
                     /translation="MIWTFYSFICVILPCLIYQIVVIKRKNLKVEKNVMIHLVWVYIF
                     LLYIYLALSKAGIGSIWDIGRYSGLFRIDEINLIPFDSVGILTYILNIIMFMPLGFLL
                     PLIWKNFRNIINVSLTGLGFSLAIELCQLFNLRATDIDDLMMDTLGAVLGYLIWVGVN
                     NLFNLIKKKDIFPSIYKNIIQDEIAITIDDDISEKITSLYKNEAIIYLILAVLGEFLL
                     FNWSIIPY"
BASE COUNT          956 a          270 c          274 g          881 t
ORIGIN      
        1 aacatacaag attctacaat aatagatttt tttgttatta ttacgagttt tttattgcaa
       61 ctgtagaata aaagtattat tatataatta agataattat ctagggaaat tttggataat
      121 caaaatatat tttataaaat caaaatacaa ttacataaac tttattaaaa atttgttggg
      181 aatttctgac taacattaag aacgtaagtt tgttggggga tggtatatgt ggaaaagtca
      241 aacactactg ttacaaaaaa agaaaaaatt gaagatatag gaatgaaatt agaacattta
      301 ttgagtgaag atattacttt ttatgaatta ttacttgaga ttttgtataa agaaaaagaa
      361 gagaattaat tctcttcttt aaggaatctt tttaaatagg cattatcaat cattttttct
      421 atagcttctc tatcttcttt ttcaagagaa tatatttttt ctaagagctt ttttgttttt
      481 tcacttactg ataagttctc tatgattaat ttatcttctt tgcttatttt tgtattatca
      541 tttacgccta ataaataatc tgttgatgtt tctaatgctt ttgctaatct aactattatt
      601 tcacttttag gttctcttaa attattttca taacgtgaca agctagcctc agttataccg
      661 actttagtag caagttcttt ttgatttata tctaattctt ttcgtagatt tgctattcta
      721 tctcctaaac tttccatatg tacatcactc cttaccgaaa ttataagtta ttttgataaa
      781 aagtaaaata aaattaccaa aaatataaaa aaaaaaggtt aaaataataa aatatattga
      841 aaattaccat ttgtatatgt ataatatgaa ttatacaaat ggtaatttga tgagaggtgg
      901 tatgttgaaa taagaaactg aattaattaa taaatacata gaaagttttg aaaaccttta
      961 attgagatat aaacaatatg tacaaaattt tttgcaagta aaattaccaa atgtataaaa
     1021 taaatcagta gcatagataa ttttatgctt taatacatta gattatttaa tttagttata
     1081 atggtcaaaa atgcaatcta caaataaaac aaagtattat ccaaaaagta ttctttaaga
     1141 aaatttttta ttagagatgt aattgatata aataatcgta ttaaaaaata aaatactaag
     1201 tttaaaaatt taaataatct ataaatcaat tataaaatat tatttcttag aaattaaaat
     1261 gaattaagta aatggaggaa ttgatatgat aataatcaga agtcaagata aaactaattt
     1321 aatgcagata aaccaaatta aaatagatgg tagtcaagtt tatgcagtat ttgaaagtaa
     1381 aattgatact gtaaaaatag gagattatga aaataataca agagctatac aagtgttgga
     1441 caatatacaa aacttcattg aaaatggaac aaaatatgat tatataacat caaataaagt
     1501 cagatacaat gttaataaaa tatttcagat gccagctaaa tagtgagtgt gcattttaat
     1561 ttaataacta aagcccactt tcttttgtag tatgaaagag ggctttacat atttgtaaat
     1621 atcgaagtac acttgtttta tcaataaatt atttaataag gtataatgga ccaattaaac
     1681 aataaaaatt ctcctaaaac agcaagtatt aaatatataa tagcttcatt tttgtaaaga
     1741 gaggtaattt tttcgcttat gtcatcatca attgtaatag caatttcatc ttgaataata
     1801 tttttatata tagatgggaa aatatctttt ttctttataa gattaaataa attatttaca
     1861 cctacccata tcaaatatcc taaaacagca cctaatgtgt ccatcattaa atcatcaata
     1921 tctgtagctc ttaagttaaa caattgacaa agttcaattg ctaatgaaaa acctaatcca
     1981 gttaatgaaa cattgataat atttctaaaa tttttccaaa ttaaaggtag taaaaatcct
     2041 aaaggcataa acataattat atttaaaata tatgttaaga tgccaactga gtcaaaaggt
     2101 attagattta tttcatcaat tctaaaaagc ccactatacc ttcctatatc ccatatgcta
     2161 ccaattccag ctttactaag tgctagatag atatataata aaaaaatata tacccatact
     2221 aaatgtatca ttacattctt ttcaactttc aaattttttc gttttataac gactatttgg
     2281 tatattaagc atggtaatat aacgcaaata aatgaataaa atgtccatat cattttattt
     2341 tgtccccttt caaatttatg tttttagttt tataagtact a
//
LOCUS       DAMKNB010000187         2317 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.193, whole genome shotgun sequence.
ACCESSION   DAMKNB010000187 DAMKNB010000000
VERSION     DAMKNB010000187.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2317)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2317)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2317
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.193"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            complement(120..2213)
                     /locus_tag="PC494_003648"
     CDS             complement(120..2213)
                     /locus_tag="PC494_003648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HDF3914097.1"
                     /translation="MNKHNFEVILNQLQINIYVTNIHTNEIIFMNKKMKEEYNILDPE
                     GKVCWQVLYPEKNSTCSFCKVLELLKNDKKGVLIKWYEKCNKLNRVFENYDSLITWQD
                     GTVVHMHQSIDIANSTSLNKPIKINEFHEISNNKEEKGVFNFSRDNFDYNSTLLYDAL
                     IRGTDEYIYICNMKTGVFRYSPSQVELFDLPGEIVENPLVYWKKIVHPEDWNRFYKSN
                     TEIGKNQMDYHTVEFRAKNRSGEYIWLRCRGQLMRDEFGEPSIFAGIMTQLGKQNKID
                     SLTQLLNYHEFMSVFEDKISNPMIEKLCIVLLNIDDFKNVNEMYDRDFGDNIIKTLAQ
                     SIQSILPDNAELYKLDGDEMGILVDNVEENEILTLYNQIQNMIIHLQLWRKYGLNITI
                     SAGCVIYPKHGDTVKELYKCASYSLQYAKEHGKNRLVFFSQEILKNKMYSLEMMRDLK
                     ASINDDFRGFSLRFQPQVDTESHKIIGVEVLLRWTNDKCKAISPLEFIPILEENDMIN
                     IVGAWVLRMALRTFRKWIDYYPFFKVSVNVSAVQILEDTFIEDIVKIIDDENFPYQNL
                     VLELTESHTVQNMSILQFKFKVLQDLGIYIAMDDFGTGYSSLEVLKFSPIDIVKIDRV
                     FVKDILKSKFDATFIHFIVAICHDVGIKVCLEGVETQEEYDLVKQIKPDYIQGYLFGK
                     PQTATEIFDLLKLDN"
BASE COUNT          778 a          390 c          229 g          920 t
ORIGIN      
        1 aacatccatt gaaatgctat tttcttatat tacaatttat aattgatata tcttcaatat
       61 aattatttaa tgtatttttg attttaaagc ttttcagtga tattattgat aaattagaat
      121 taattatcta gctttaaaag gtcaaagatt tctgttgctg tctgcggttt tccaaataaa
      181 tatccttgta tgtaatctgg ctttatttgt ttaactaaat catactcttc ttgtgtttct
      241 acaccttcta aacatacttt tattcctacg tcatgacaaa ttgcaacaat aaaatgtata
      301 aatgtagcat caaacttact ctttaatata tctttaacaa atactctatc aattttcact
      361 atatctattg gagaaaattt taaaacttct agagacgagt atcccgtacc aaaatcatcc
      421 atagcaatat aaattcctaa atcttgtaaa accttaaatt taaactgtaa aatactcata
      481 ttttgtactg tatgactttc tgtcaattct aaaacaagat tttgataagg aaaattttca
      541 tcatctataa tttttactat atcttcaata aatgtgtctt ctaatatttg aacagctgaa
      601 acgtttacac tcactttaaa aaaaggatag taatcaatcc atttcctaaa agtacgtaat
      661 gccattcgaa gcacccaagc ccctacaata tttatcatat cattttcttc taatattgga
      721 ataaattcca aaggagaaat tgctttgcat ttgtcattag tccaccttaa aagaacttct
      781 acacctatta ttttatgact ttctgtatct acttgtggct ggaatcgaag actaaacccc
      841 ctaaaatcat cattaattga tgcctttaaa tcccgcatca tttctaatga atacatttta
      901 ttttttaata tttcttggga gaaaaaaaca agcctgtttt taccatgctc tttcgcatat
      961 tgtaaagagt aactagcaca cttataaagt tcttttactg tatctccatg ctttggatat
     1021 attacacaac cagcagaaat tgttatattt aatccatatt ttctccatag ttgaagatgt
     1081 ataatcatat tctgtatttg attatataga gttagaattt cattttcttc aacattatca
     1141 acaagaatac ccatttcgtc cccatcaagt ttataaagtt cagcattatc tggtaaaata
     1201 gattgtatag actgtgctag tgtttttatt atattatctc caaaatccct atcatacatc
     1261 tcattaacat ttttaaaatc gtcaatattt aataatacta tgcataattt ttcaatcata
     1321 ggatttgaaa ttttatcttc aaatacactc ataaattcat gataattcag taactgtgtc
     1381 aatgaatcaa tcttattttg tttacctaat tgcgtcatta ttcctgcaaa aatacttggt
     1441 tctccaaatt catcacgcat tagttgacct ctacatctta accatatata ttctccacta
     1501 cgatttttag ccctaaattc cactgtatga taatccatct ggtttttacc tatttcagtg
     1561 tttgacttat aaaaacgatt ccagtcttct ggatgtacaa tttttttcca gtaaacaagc
     1621 ggattttcaa caatttctcc tggtaagtca aataattcaa cttgtgatgg tgaatatcga
     1681 aatacgcctg ttttcatatt gcaaatgtat atatattcat ctgtacctct aatcaaagca
     1741 tcataaagca atgtagaatt ataatcaaaa ttgtctcttg aaaaattaaa aactcctttt
     1801 tcttctttat tatttgatat ttcatgaaat tcattaatct taattggttt atttaagctt
     1861 gttgagtttg caatatctat tgattgatgc atatgaacaa ctgtgccatc ttgccatgta
     1921 attaaactat cataattttc aaaaacacga tttaacttat tacatttttc ataccacttt
     1981 attaatactc cttttttatc attctttaat aattctaaaa ctttacaaaa actacaagta
     2041 gaattttttt caggatataa tacttgccaa caaacttttc cttctggatc taaaatatta
     2101 tattcttctt tcattttttt gttcataaaa ataatttcat tagtatgaat atttgtaaca
     2161 tatatattaa tctgtagttg atttaatata acttcaaaat tatgtttgtt catatactta
     2221 tctcctccat agttactgct ctttataaca acattgttaa aattattctt tttagaagat
     2281 ttacttataa cttatacata tacactaaat accttaa
//
LOCUS       DAMKNB010000188         2192 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.194, whole genome shotgun sequence.
ACCESSION   DAMKNB010000188 DAMKNB010000000
VERSION     DAMKNB010000188.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2192)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2192)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2192
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.194"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            145..2169
                     /locus_tag="PC494_003649"
     CDS             145..2169
                     /locus_tag="PC494_003649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009899983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDF3914098.1"
                     /translation="MDKKKLILITHDKLNSDHYKEELTNFFGDEIIIETQNILDGIKE
                     NLEGDVVLSLSPLTSNFLIKHFKEDIEIIHGTKALSKLGYEKMMKLPPGTKSLLMTTN
                     KTSAFEMATYLYKIGINHIDFVPTYPDCDEIYDLDTAITPGQIRFIPKYIKNIVDLGW
                     RKISLDTYMSLLVVLKLKNEKFIEKLYKLSKETLSHDFLNTSLDNISKLKTILYMTID
                     EIGDGLIFFNTFNKVTFVNKSLLNMLGLDEKLIKSPSLMEYMPNSFLDKITKNLNIDN
                     MIIYIDEIDKKFILSKKPFYLYKNIEGCLITLKDVNNIEILEQKIRSDSVKRGYVAKY
                     KFNNIIGNSSIIKDCIKKAKKMALTDNPILITGETGTGKEAFTQSIHNHSNRKNKPFV
                     AINCASLPSELLESELFGYEDGSFTGAKKGGKKGLFELAHTGTIFLDEIGDMPHDLQV
                     KLLRVLQEKEIRKIGGTSIIPIDVRILAATNKDLEKLIIENKFRMDLFYRISMFTLDL
                     PPLRKRLEDIPLLLESFLKELPYKNIKLDKSLLEALNSYTWMGNIRELRNCIEYMAYM
                     GSNYLTINDLPQNISSKLNNNHMSSNMSIFNDLNQYDKNICISILKSLHMKPMGRTKL
                     MKFMEYNVTEYEVRNMLEYLTRNGYLISSKGRKGSSITEKGIKIIENNII"
BASE COUNT          932 a          259 c          304 g          697 t
ORIGIN      
        1 aataggtttt tataggataa aatcctaaaa aaacctatta tttaatcaaa tatataaatt
       61 tatactacta tttgttgtat aatataactt gccttatact ttaaatactt taaaaataaa
      121 tactattttg ttaggagaaa taaaatggat aaaaagaagt taatccttat aacacatgat
      181 aaattgaata gtgaccacta caaagaagaa ttaacaaact tttttggaga cgaaataatc
      241 atagaaacac aaaatatact tgatggaata aaagaaaatt tagagggaga tgtagtgctt
      301 tctctatcac ctttaactag taatttttta ataaaacatt ttaaggaaga tattgaaatt
      361 attcatggaa cgaaagcact ttcaaaactt ggatatgaaa aaatgatgaa actacctcca
      421 ggtacaaaat cgttacttat gacaaccaat aaaacttcag catttgagat ggctacttat
      481 ctatataaaa ttggtataaa tcatatagat tttgtaccga catatccaga ttgtgatgaa
      541 atatatgatt tagatacagc tataacacca ggtcagatta gatttatacc aaaatacata
      601 aaaaatattg ttgatttagg ttggagaaaa atctcattag atacatatat gtcattatta
      661 gtagtattaa aactaaaaaa tgagaaattt atagaaaaac tatacaaatt gtccaaagag
      721 acactaagtc atgatttctt aaatacatca ttagataata tatctaaatt aaaaactata
      781 ctttacatga ccattgatga aataggtgat ggtctaatat ttttcaacac ctttaacaag
      841 gttacttttg taaataagtc tttacttaat atgttgggac tagatgaaaa acttataaaa
      901 tcaccttcct taatggaata tatgccaaat agtttcttag ataaaattac aaagaactta
      961 aatatcgata atatgattat atacatagac gaaatagata aaaaattcat actttctaaa
     1021 aaaccatttt atctttataa aaatatagag ggttgcttaa ttacattgaa agatgtaaac
     1081 aatatagaaa tattagaaca aaaaataaga agtgattctg tcaaaagagg ttatgtagct
     1141 aaatataaat ttaataatat tattggaaat agttctatta taaaagattg tattaaaaag
     1201 gcaaaaaaaa tggctcttac agataatcct atattaataa caggtgaaac aggaacaggt
     1261 aaagaagcct ttactcagtc aatacacaat cattcaaata gaaaaaataa accttttgta
     1321 gcaataaatt gtgcttcatt accaagtgaa ttacttgaaa gtgaactatt tggatatgaa
     1381 gatggttctt ttactggagc aaaaaaaggt ggaaaaaaag gattattcga attagctcac
     1441 actggcacta tatttttaga tgagatagga gatatgccac atgatttaca ggttaaactt
     1501 ttaagagtct tacaagaaaa agaaattaga aaaattggtg gtacaagtat tattccaatt
     1561 gatgtgagaa tattagctgc cacaaataaa gatttagaga aattaattat agaaaataaa
     1621 tttaggatgg atttatttta taggataagt atgttcactt tagatttacc tcctcttaga
     1681 aagagattag aagatatacc tcttctttta gaatcatttt taaaagaact tccctataaa
     1741 aacataaaac tcgataagag tcttttagaa gctttaaatt catacacttg gatggggaat
     1801 attagagaac tgagaaattg tattgaatat atggcttaca tgggttccaa ttatcttaca
     1861 ataaatgatt tacctcaaaa catatcttca aaattaaata ataatcatat gtcaagtaat
     1921 atgtccatat tcaatgattt aaaccaatat gacaaaaaca tatgcatttc tatcctaaaa
     1981 tcattgcaca tgaaaccaat ggggaggaca aagttaatga aatttatgga atataatgtc
     2041 acagaatacg aagtaagaaa tatgctagaa tatttgacac gcaatggata cttaatttct
     2101 agtaaaggaa gaaaaggctc atcaataact gagaaaggca taaaaataat agaaaataat
     2161 ataatttaaa cctatagtaa ttcatcttta ct
//
LOCUS       DAMKNB010000189         1997 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.195, whole genome shotgun sequence.
ACCESSION   DAMKNB010000189 DAMKNB010000000
VERSION     DAMKNB010000189.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1997)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1997)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1997
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.195"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            137..1348
                     /locus_tag="PC494_003650"
     CDS             137..1348
                     /locus_tag="PC494_003650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
                     /protein_id="HDF3914099.1"
                     /translation="MKGLVLEGGGTKGAYQIGAYKALRELGIEFQGVTGTSIGALNGA
                     YIVQNDIEVMEDIWLNYDYTHFMNIDRETYERFKNVDFTTKNLNAVFELINKARKNEG
                     IDISPLRQLMETTLNEDIIRKSKKDFGLVTVWWDKKINPYPLYIEDIPKGRLIDYLIA
                     SSSLPIFQTNMMDDKLYLDGMFCDNMPIGLLEDKGYEDVVVIRLIDDFIGKMNLNRHQ
                     NINIKTIIPSEYLGGSLNKDRDNVEKNIRLGYLDTMKAYERCTGIKYYFDVEYKYNEE
                     YCFDKFRSMSNETIQYICNLLNIKRDASLRTVMESVIPKLGEVLGLPKDFSYKDLFYC
                     IYEKKLEENNINRIKLYDFNKVIDVVNTNIDSNRNLASNFEVRPKISIKKNKNTKLLT
                     NCIIKDIKNQS"
     gene            1541..1801
                     /locus_tag="PC494_003651"
     CDS             1541..1801
                     /locus_tag="PC494_003651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr family phosphocarrier protein"
                     /protein_id="HDF3914100.1"
                     /translation="MEKVVSIKNASGLHARPAGMFVKKAAEFKSTVEVVAKDKTVNAK
                     SIMGIMSLGLAQGEELKLVVNGEDEEVALAAMVELVESGFGE"
BASE COUNT          841 a          174 c          350 g          632 t
ORIGIN      
        1 ttttcaatat ttttttgata aaataagaat gaatttgtgc aattttattt ttctccaata
       61 actaaaaata gttttttgaa ttaatatttg cttaagaata aaaatcagaa acgtttttga
      121 tatagtaggt gataatatga aaggattagt tttagaaggt ggaggaacaa aaggagccta
      181 ccaaataggt gcatataaag ctttaagaga gcttggtata gagtttcaag gagtaactgg
      241 cacatcaatt ggtgctttaa atggagcata tatagttcaa aatgatattg aagtaatgga
      301 agatatttgg ttaaattatg actatactca ttttatgaat attgatagag aaacctatga
      361 gaggtttaaa aatgtagatt tcactactaa aaatctcaat gcagtgtttg agcttataaa
      421 taaagctaga aaaaatgaag gtatagatat aagcccatta agacaactaa tggagacaac
      481 attaaatgaa gacataataa ggaaatcaaa aaaagacttt ggacttgtta cggtctggtg
      541 ggataaaaaa attaatccat atccattgta tatcgaagat atacctaaag gaagattgat
      601 tgattattta attgctagtt ccagtttgcc tatttttcaa acgaacatga tggatgataa
      661 gttgtatctt gatggaatgt tttgtgataa catgccaata ggactcttgg aagacaaagg
      721 ttatgaagat gttgttgtaa ttaggttgat tgatgatttt attgggaaaa tgaatctaaa
      781 tcgacatcaa aatataaata taaaaactat aataccatca gaatatctag gaggttctct
      841 taataaagat agagataatg tagaaaaaaa catccgacta ggttacttag atactatgaa
      901 agcatatgaa agatgcactg gaattaagta ttattttgat gtagagtata aatataatga
      961 agaatattgt tttgataaat ttagaagtat gagtaatgaa acaatacaat atatctgtaa
     1021 tttattgaat ataaaaagag atgcttcact tagaaccgtt atggaaagtg taataccaaa
     1081 gcttggtgag gtgcttggat tgccaaagga tttttcatat aaagatttgt tttactgtat
     1141 atatgaaaag aaacttgaag aaaataatat aaacaggata aaattatatg attttaacaa
     1201 ggttatagat gttgtaaata caaatattga ttctaataga aatttagctt ctaattttga
     1261 agttagacct aaaattagta ttaaaaagaa caaaaacaca aaattattga caaattgtat
     1321 tataaaagac ataaaaaatc aaagttaaat aaaaaacaaa aaaaaatttg taattatact
     1381 cgaaaaaagt gtatattagt agtataatat ttttgtagca ctagtgggaa caaaaaatga
     1441 ccataggaca aaaaagtacc acttagtacc attaaagtaa aaaacaggaa aacaatttta
     1501 aaaaatataa aatgtaaagt ttataggagg atttaaaaaa atggaaaaag tagttagtat
     1561 caaaaatgca agtggattac atgctagacc agcaggaatg tttgttaaga aggcagctga
     1621 atttaaatca acagtagagg ttgtagcaaa agacaaaact gtaaatgcaa aatcaataat
     1681 gggaataatg agtttaggtt tagctcaagg agaagaatta aagttagttg taaatggaga
     1741 agatgaagaa gtagctttag ctgcaatggt tgaattagtt gaaagtggat ttggagaata
     1801 gatataataa ttttttaaaa atttgatatt tagaatctaa tattacttaa agtaaagtaa
     1861 cagagaagta ttaaacatat acagaccaac atttgtagat atttaatttc tttgttactt
     1921 tcatgtttat ttaatcagaa gattaagact attgttaatt gggtataaaa atataaatat
     1981 tttagaaaat gaaataa
//
LOCUS       DAMKNB010000190         1979 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.196, whole genome shotgun sequence.
ACCESSION   DAMKNB010000190 DAMKNB010000000
VERSION     DAMKNB010000190.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1979)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1979)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1979
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.196"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            complement(57..1274)
                     /locus_tag="PC494_003652"
     CDS             complement(57..1274)
                     /locus_tag="PC494_003652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallo-hydrolase"
                     /protein_id="HDF3914101.1"
                     /translation="MLGKKCMDYLQTLGKISSTTNGLTRLILTQEHKKSIDLISSWME
                     GLNLDIEIDDIGNVIGTYKSSFPNAPTLVVASHQDSVKCGGIFDGMLGIIVPLVGLEE
                     AKHNNRSYPFNIKLIAFAEEEGTRFETSLMGSKVFAGTFKEELLKSVDENGITLEEAV
                     TKFGFNTKNLTNLHPRKDVDAYLEFHIEQGPVLENESLPAGIVSSITGFKSFKISVNG
                     KSGHAGTLPMNMRLDAGCCACECVLAIEKVAKTTTDLVATVGKMNFYPSSSNVVPERA
                     EFTLDVRSCSQEILDNSVEKIFNEISHICENRKLNYTSELAFENVPVPCSNKITKIIE
                     KSFIDLNLNPFYIYSGAGHDAQEMDNITDIGMVFIRCAGGVSHNPNESVSVDDLDTAV
                     KIFLKILDNLDLK"
     gene            complement(1465..1878)
                     /locus_tag="PC494_003653"
     CDS             complement(1465..1878)
                     /locus_tag="PC494_003653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDF3914102.1"
                     /translation="MELEITEKIEKQDEDTIFQGLLKYNLARLEDKNPVDLGIYIRDK
                     AGKIVAGFIGVTHGNWLSIKYLWVSEKLRYKGTGSQLLYKAEKIAKERGCKYVFLDTF
                     SFQAPKFYEKFGYHKVFSLENYPLTGKRYYYRKIL"
BASE COUNT          677 a          323 c          225 g          754 t
ORIGIN      
        1 taaatataaa gtgatttttt agattatata ttttaatata ctttcttata taagaattat
       61 tttaaatcaa gattatctag tatttttaaa aatattttta cagcagtatc caagtcatct
      121 acagaaacac tttcattagg attatgactt acgcccccag cgcatcttat aaataccata
      181 ccaatatcag ttatattatc catttcctga gcatcatggc cagcaccact ataaatataa
      241 aaaggattaa gatttaaatc tataaaactt ttttctatga tttttgttat tttattagaa
      301 catggtacag gaacattttc aaaagcaagt tcacttgtat aattaagttt tctattttca
      361 catatatgtg atatttcatt aaatatcttt tctacagaat tatcaagaat ttcttgtgaa
      421 caagagcgta catcaagagt aaattcagct ctttcaggta ccacatttga tgaagatgga
      481 tagaaattca tctttcctac agtagcaacc aaatcagtag tcgttttagc tactttttcg
      541 atagctaata cacattcaca ggcacaacat ccagcatcaa gtctcatatt cattggaagt
      601 gtaccagcat gtccagactt accatttact gatatcttaa aacttttaaa tcctgtaata
      661 cttgatacaa ttccagcagg aagagattca ttttctaaaa caggaccctg ctcgatatga
      721 aattctaaat atgcatctac atcttttcta ggatgcaaat ttgttaagtt ttttgtatta
      781 aatccaaact ttgttacagc ttcttcaagt gtaattccat tttcatcaac agatttaaga
      841 agttcctctt taaaagtacc agcaaaaact ttacttccca ttaaagaagt ttcaaatcta
      901 gttccttcct cttcagcgaa agcaattagc ttaatattga aaggataaga cctattattg
      961 tgttttgctt cttcaagacc aactagaggc actattatac ctaacatacc atcaaatata
     1021 cctccacact ttacactatc ttgatgagat gcaactacta atgtgggagc atttggaaag
     1081 cttgatttat atgtacctat aacgtttcca atgtcatcaa tttcaatatc aagatttaaa
     1141 ccttccatcc atgaactaat taaatcaata gattttttat gttcttgagt caagataagt
     1201 cttgtaagac catttgttgt tgaacttatt tttcctaatg tttgtagata atccatacat
     1261 ttttttccta acatatttac ctcctaaaaa tataattttt atttaagcta agattagctt
     1321 ttatacttat aatttttgaa ctttcaaata attttgtatg tatagtaaaa tactatttta
     1381 gtattaataa tgatataaaa acataaagtc tgtagacgaa gagcagaagt tttaatttaa
     1441 aaatatgaaa tatgattttt attattatag tatttttcta taataatatc tctttccagt
     1501 tagaggataa ttttcaagtg aaaatacttt atggtatcca aatttctcat aaaatttagg
     1561 tgcttgaaaa ctgaatgtat ctaaaaaaac atatttacaa cctcgttctt tagcaatttt
     1621 ttcagcctta tataaaagtt gacttccagt acctttatat ctaagcttct cactaaccca
     1681 taagtatttt atagaaagcc aattaccatg agtaacacct ataaaacctg caacaatttt
     1741 acctgcttta tctcgaatat atattcctaa atccactggg tttttatctt caagtctagc
     1801 aagattatat tttaataatc cttgaaaaat agtatcttca tcttgttttt ctattttttc
     1861 tgtaatttct aattccatat ttgaactttc tccttgtata atcttttgta tattggtatt
     1921 ttttaataaa atcagtagaa agaatatagt ttaacattat tctaataggc atttatgct
//
LOCUS       DAMKNB010000191         1976 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.197, whole genome shotgun sequence.
ACCESSION   DAMKNB010000191 DAMKNB010000000
VERSION     DAMKNB010000191.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1976)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1976)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1976
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.197"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            88..486
                     /locus_tag="PC494_003654"
     CDS             88..486
                     /locus_tag="PC494_003654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3914103.1"
                     /translation="MNKKKKLIGIAISFLLIISIINPLQVEAEAIIESSVYISSIKEN
                     YTYDNTKFKTIKSKSRHKSRKYNKSKVKLKKRSIRTKKYGYQTINKYKRQNTRRHNIL
                     TKLILSIIVIFLVIVLVVLIFIKRKKKKFY"
     misc_binding    922..1185
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            1336..1887
                     /locus_tag="PC494_003655"
     CDS             1336..1887
                     /locus_tag="PC494_003655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan transporter"
                     /protein_id="HDF3914104.1"
                     /translation="MKTNTKKLTLNAILLAMGLLIHQITPAIGLPMKPDVPLAMLFVI
                     LVLNRDDYKTCLIAGIVTGIFTALTSSFPGGQIPNVIDKTLTANIVFLLMNISYNMPF
                     IKKLAKKTQDTVVVAIIMPIGTLVSGTIFLLAAQAIVGLPGASFTALFLAVVLPAVLI
                     NLVAGIFLFKIVSLSIRRVSYQA"
BASE COUNT          835 a          186 c          296 g          659 t
ORIGIN      
        1 gatatataag aaacttgaaa aatttgtaat ttttagttat atatatatta taatgaacta
       61 gttaaaaatt tttatgaggg ggaaaatatg aataagaaga aaaaattgat tgggatagct
      121 atatcttttc tacttataat cagcattata aatccattac aagtagaagc agaagctatt
      181 attgagtcta gtgtatacat ttcttcaata aaagagaatt atacatatga taatactaaa
      241 tttaaaacta ttaaatctaa aagtagacat aaaagtagga aatataataa aagtaaagta
      301 aagttgaaaa aacgaagtat aagaactaaa aagtatggat atcaaactat aaataaatat
      361 aaaagacaaa acacaagaag acataatatc ctaacaaaat taatattgtc cataatagtc
      421 atatttttgg ttatagtttt agtagtgcta atatttatta aaagaaagaa gaaaaaattt
      481 tactaaaaat aattaaaaga atatcatttt tttaatcatt ggtatctatt taataatatg
      541 atgtaattaa aatggagtaa tattctgttt caaaggaggc atataaatac aggaatgagt
      601 attaaatgat ggttaattaa gtaaatttat tgataaatgt acttaattaa ctttgaagaa
      661 tttaattcct catgaatcaa aatataaaat tacatcaaca gttattcaca aaattaatat
      721 aagaagaatt agagtcaaag agcagactat tagaccatta aagtaattat tcatagaatt
      781 ttgtatatga aaagaaatgt atagtataat ttactttttt tataaaaaat agattacaaa
      841 atatattttt tataaaaagg tattgacatt ttttagaaaa aagaatatca ttattttaac
      901 aacaaaattc aatacaataa attaaatcct atgacaagga agagtagtta aatttaggtt
      961 cagtatagag agctgaggat ggtggaatct tagcaagaaa aaatttgatg aatggccctt
     1021 agaggaataa attgaaatca tagttttgag agtagacttt atcgtcagtc gcacgttata
     1081 gcgaataagg tatgtaagta cctgataatg agatgtatga aaattgaatt ttatattaat
     1141 ttttatataa tttaggtggc aacgcggata atctccgtcc tattagttta ggacggagtt
     1201 ttttatttta ctgaaaattt aaaagataga aggtggtgag aaagatgtta tgaatttcaa
     1261 aagctaaaga tgatgatata gtaggttggc aaaaaaataa attgaaaatt aaaaaaatag
     1321 gaggaagtac aaaaaatgaa aacaaataca aaaaaattaa ctttaaatgc aatactttta
     1381 gcgatgggat tattaataca tcaaatcaca ccagctatag gattaccaat gaagccagat
     1441 gtaccactag caatgttatt tgtaatattg gttttaaata gagatgatta taaaacttgt
     1501 ttgatagcgg gtatagtaac aggaatattt acagcactta catcaagttt tccgggaggt
     1561 caaattccta atgtaataga taaaactctt acagcaaata tagtattttt attaatgaat
     1621 attagttata atatgccttt tataaaaaaa ttagctaaga aaacacaaga tactgtagta
     1681 gttgcaataa taatgccaat aggaactctt gtaagtggaa ctatcttttt attagcagct
     1741 caagctatag ttggtcttcc aggggcttca tttacagctt tattcttagc agtagtatta
     1801 ccagctgttt taataaatct agttgcagga atatttttat tcaagattgt tagtctatca
     1861 ataagaagag ttagttatca agcttaaaca cgaaataata ttttacttta taaagcatta
     1921 taataactaa ataacataag aataaagtag attataacta ttttattctt atgttg
//
LOCUS       DAMKNB010000192         1925 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.198, whole genome shotgun sequence.
ACCESSION   DAMKNB010000192 DAMKNB010000000
VERSION     DAMKNB010000192.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1925)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1925)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1925
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.198"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            119..235
                     /gene="rrf"
                     /locus_tag="PC494_003656"
     rRNA            119..235
                     /gene="rrf"
                     /locus_tag="PC494_003656"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
     gene            242..316
                     /locus_tag="PC494_003657"
     tRNA            242..316
                     /locus_tag="PC494_003657"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:274..276,aa:Asn,seq:gtt)
     gene            321..395
                     /locus_tag="PC494_003658"
     tRNA            321..395
                     /locus_tag="PC494_003658"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:354..356,aa:Glu,seq:ttc)
     gene            401..476
                     /locus_tag="PC494_003659"
     tRNA            401..476
                     /locus_tag="PC494_003659"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:434..436,aa:Val,seq:tac)
     gene            482..558
                     /locus_tag="PC494_003660"
     tRNA            482..558
                     /locus_tag="PC494_003660"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:516..518,aa:Asp,seq:gtc)
     gene            569..643
                     /locus_tag="PC494_003661"
     tRNA            569..643
                     /locus_tag="PC494_003661"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:601..603,aa:Thr,seq:tgt)
     gene            658..742
                     /locus_tag="PC494_003662"
     tRNA            658..742
                     /locus_tag="PC494_003662"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:692..694,aa:Tyr,seq:gta)
     gene            752..825
                     /locus_tag="PC494_003663"
     tRNA            752..825
                     /locus_tag="PC494_003663"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:784..786,aa:Gly,seq:tcc)
     gene            836..912
                     /locus_tag="PC494_003664"
     tRNA            836..912
                     /locus_tag="PC494_003664"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:870..872,aa:Arg,seq:tct)
     gene            922..997
                     /locus_tag="PC494_003665"
     tRNA            922..997
                     /locus_tag="PC494_003665"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:955..957,aa:Gln,seq:ttg)
     gene            1009..1084
                     /locus_tag="PC494_003666"
     tRNA            1009..1084
                     /locus_tag="PC494_003666"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1042..1044,aa:Lys,seq:ttt)
     gene            1087..1175
                     /locus_tag="PC494_003667"
     tRNA            1087..1175
                     /locus_tag="PC494_003667"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1121..1123,aa:Ser,seq:tga)
     gene            1193..1283
                     /locus_tag="PC494_003668"
     tRNA            1193..1283
                     /locus_tag="PC494_003668"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1227..1229,aa:Ser,seq:gct)
     gene            1292..1368
                     /locus_tag="PC494_003669"
     tRNA            1292..1368
                     /locus_tag="PC494_003669"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1326..1328,aa:Pro,seq:tgg)
     gene            1454..1529
                     /locus_tag="PC494_003670"
     tRNA            1454..1529
                     /locus_tag="PC494_003670"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1487..1489,aa:Trp,seq:cca)
     gene            1590..1666
                     /locus_tag="PC494_003671"
     tRNA            1590..1666
                     /locus_tag="PC494_003671"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1624..1626,aa:Pro,seq:tgg)
     gene            1673..1749
                     /locus_tag="PC494_003672"
     tRNA            1673..1749
                     /locus_tag="PC494_003672"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1707..1709,aa:Ile,seq:gat)
     gene            1753..1828
                     /locus_tag="PC494_003673"
     tRNA            1753..1828
                     /locus_tag="PC494_003673"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1786..1788,aa:Phe,seq:gaa)
     gene            1836..1912
                     /locus_tag="PC494_003674"
     tRNA            1836..1912
                     /locus_tag="PC494_003674"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1870..1872,aa:Met,seq:cat)
BASE COUNT          485 a          442 c          523 g          475 t
ORIGIN      
        1 attcattaag atatatgtgc agtttttaga gtgttaactc taaaaaaaaa taaaaaaagt
       61 attgacaaaa atagtaaaaa atgttaatat tatacttgtc ctagcaacaa gaaaaaaatg
      121 tggttataat agcggagaag atacacctgt ttccattccg aacacagaag ttaagttctc
      181 tagcactgat ggtacttggt gggaaactgc ctgggagagt aggacatagc cacgtgaatg
      241 ttccaaggta gctcaacggt ggagcaaccg gctgttaacc ggtaggctgt gggttcgagc
      301 cccacccttg gagccattat ggctcgttgg tcaagaggtt aagacaccgc cctttcacgg
      361 cggtaacagg ggttcaattc ccctacgagt caccatttgt gggatcatag ctcagctggg
      421 agagcacctg ccttacaagc agggggtcac aggttcgagc cctgttggtc ccaccatttg
      481 cggcctggta gttcagttgg ttagaatgcc agcctgtcac gctggaggtc gagggttcga
      541 gccccttcca ggtcgccaaa ataaaaatgc tggtgtggct caacggtaga gcagctgact
      601 tgtaatcagc aggttgtagg ttcgattcct atcaccagct ccatgtaaaa ctaatacgga
      661 ggatttcccg agcggccaaa gggggcagac tgtaaatctg ttgtcatcga cttcggtggt
      721 tcgaatccac catcctccac caattaaata tgcgggtgta gctcaatggt agagttctgg
      781 ccttccaagc cagctgtgag ggttcgatcc ccttcacccg ctccaaagaa agcgtgggtg
      841 catagctcag ctggatagag caacgccctt ctaaggcgtg tgtccggggt tcgaatccct
      901 gtgcgctcac cacatatata ttggggatta gccaagtcgg taaggcacat gactttgact
      961 catgtatgcg taggttcgag tcctgcatcc ccagccaaat aaaaatatgg tctattagct
     1021 cagtcggtag agcacctgac ttttaatcag ggtgtcccgc gttcgagtcg cggatagatc
     1081 accaatggag aggtgtccga gtggtttaag gagctggtct tgaaaaccag tgacttcgaa
     1141 aggggccgtg ggttcgaatc ccaccctctc cgccaaaaaa atgactgaat ttggagaagt
     1201 actcaagtgg ctcaagagga tcccctgcta agggattagg ctgggtaacc ggtgcgaggg
     1261 ttcgaatccc tccttctccg ccattcaaaa acgaggtgta gcgcagtttg gtagcgcaca
     1321 tggtttggga ccatggggcc gggggttcga gtcccttcac ctcgaccaac ttaagctttt
     1381 agttcagttg gttagagtgc ccaactcatg gctagtaatt ctagggtttg agtccatgaa
     1441 ggttattctt cataggggtg tagctcagtt ggtagagcgt cggtctccaa aaccgtgcgc
     1501 cgggggttcg agtccctcca cccctgccaa ataaaaagga cttgaaaaaa gttggatttt
     1561 agagtagtat aagatagtaa ataagatttc gaggtgtagc gcagtttggt agcgcacatg
     1621 gtttgggacc atggggccgg gggttcgagt cccttcacct cgaccaagaa aagggcctat
     1681 agctcaggtg gttagagcgc acgcctgata agcgtgaggt cgctggttcg agtccagcta
     1741 ggcccaccat ttgcccagat agctcagtcg gtagagcagg ggactgaaaa tccccgtgtc
     1801 ggtggttcga ttccgcctct gggcaccagg aatacggcgg tatagcttag ttggctagag
     1861 cgttcggttc atacccgaaa ggtcataggt tcgactccta ttaccgctac catctaacta
     1921 tatca
//
LOCUS       DAMKNB010000193         1893 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.199, whole genome shotgun sequence.
ACCESSION   DAMKNB010000193 DAMKNB010000000
VERSION     DAMKNB010000193.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1893)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1893)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1893
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.199"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            45..1757
                     /gene="ptsP"
                     /locus_tag="PC494_003675"
     CDS             45..1757
                     /gene="ptsP"
                     /locus_tag="PC494_003675"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HDF3914105.1"
                     /translation="MAYKGIGASPGVALGKALVVEHSELVIEKKSIDNVEAEIAKLED
                     AVAVSKEELVKVKEKASEELGAEEAEIFEAHLLVLEDPELIGSAIDKIKTESVNAEYA
                     LNEIKEMFVSMFESMDNEYMKERAADIKDVTNRILRHILGIKVVDLSALSEEVVLIAH
                     DLTPSDTATMNKKMVLGFLTDIGGRTSHTAIMSRTLEIAAIVGLNDITSKVKDGDFVV
                     FNGDTGEVIVNPDEETINKYTELKAKYEDERKALQLLKGKPSVTLDGKHVELAGNIGT
                     PNDIEGLIKNDAEGVGLYRTEFLYMDRDSFPTEEIQYEAYKAVLEGMDGKPIVIRTLD
                     IGGDKELSYLSMEPEMNPFLGYRAIRLCLDRKDIFKTQLRALYRASVHGRLRIMFPMI
                     SSLEELLQAKEVVKEVLAELDSEGVAYAKDVEIGMMIEVPSAAVISDVLAKHVDFFSI
                     GTNDLIQYTCAVDRMNQKISYLYNQFNPAVLRLIKTVIDNAHKEGKWAGMCGESAGDQ
                     KMIPILLGMGLDEFSMSPISILPARKLITSVKESDMKKLADDVFNMGTAEEIKSYIEK
                     TFNI"
BASE COUNT          729 a          200 c          375 g          589 t
ORIGIN      
        1 tataaagttt atgtgctaga tgatattttt taggaggtag ggttatggct tacaaaggaa
       61 taggtgcttc tcctggtgtt gctttaggga aagcgttagt agttgaacat agtgaattag
      121 taattgaaaa aaaatctata gataatgttg aagctgaaat tgctaaatta gaagatgcag
      181 ttgcagtttc taaagaagaa ttagtaaaag ttaaggaaaa ggcttctgaa gaattaggag
      241 cagaggaagc agaaatattt gaagcacatt tattagtttt agaagaccca gagttaattg
      301 gttctgcaat agataaaatt aaaactgaaa gtgtaaatgc agagtatgct ttaaatgaaa
      361 taaaagagat gtttgttagc atgtttgagt ctatggacaa tgagtacatg aaagaaagag
      421 cggcagatat aaaagatgtt acaaatagaa tacttagaca tatattagga attaaagttg
      481 ttgatttatc tgctttaagc gaagaagttg tattaatagc acatgattta actccatcag
      541 acacagcaac tatgaataaa aaaatggttt taggattttt aactgatata ggtggaagaa
      601 cttctcatac tgctatcatg tctagaactt tagaaatagc tgcaatcgtt ggattaaatg
      661 atataacttc aaaagttaag gatggagatt ttgtggtttt caatggagac acaggtgaag
      721 taatcgtgaa tcctgatgaa gagactataa ataaatatac tgaattaaaa gctaagtatg
      781 aagatgagag aaaagcatta cagctattaa aaggaaaacc atctgtaact ttagatggaa
      841 aacatgtgga attagctggt aacataggaa cacctaacga tatagaaggt ctaataaaga
      901 atgatgctga aggtgttggt ctttatagaa cagaattttt atacatggat agagattctt
      961 tcccaacaga agaaatacaa tatgaagcat acaaagctgt attagaagga atggatggaa
     1021 agcctatagt tataagaaca ttggatatag gtggagataa agaattaagt tatttaagta
     1081 tggaacctga aatgaatcca ttcttaggtt acagagcaat aagactttgc ctagatagaa
     1141 aagatatatt taagactcaa ttgagagctt tatatagagc tagtgttcat ggaagattaa
     1201 gaatcatgtt cccaatgatt tcatctttag aagagttgtt acaagctaaa gaagttgtaa
     1261 aagaagtttt agcagaactt gattctgaag gtgtggctta tgctaaagat gtagaaattg
     1321 gtatgatgat agaagttcca tctgctgctg tgatatctga tgtattggct aaacacgtag
     1381 atttcttctc tataggaact aatgatttaa ttcaatacac ttgtgcagtt gatagaatga
     1441 atcaaaagat aagttatctt tacaatcaat ttaatccagc tgttttaaga cttataaaga
     1501 ctgttataga caatgcacat aaagaaggaa aatgggcagg tatgtgtgga gaatctgctg
     1561 gagaccaaaa aatgatacca atacttttag gtatgggatt agacgagttc tctatgtctc
     1621 caatatcaat acttcctgct agaaagttaa taacttcagt taaagagtca gatatgaaaa
     1681 aattagctga tgatgtattt aatatgggta ctgctgaaga aataaaaagc tatatagaaa
     1741 agacttttaa tatataatta atgttatata gttactaaaa ttcatttttc taaataacaa
     1801 aattatattt tacgaataaa aaaactatag tatatcatat atactatagt ttttttgtta
     1861 tataaattac gtatcaaaat ttgtaaaatg aat
//
LOCUS       DAMKNB010000194         1823 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.200, whole genome shotgun sequence.
ACCESSION   DAMKNB010000194 DAMKNB010000000
VERSION     DAMKNB010000194.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1823)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1823)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1823
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.200"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            complement(83..331)
                     /locus_tag="PC494_003676"
     CDS             complement(83..331)
                     /locus_tag="PC494_003676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HDF3914106.1"
                     /translation="MQKTKAWGIIEPEKPESQQQMAHMDFAVNDLEEAVQYAIHCGAT
                     IAEEQFTDDWRVMIDPAGHPFCLCQMKSIMESSHFSLL"
     gene            complement(362..823)
                     /locus_tag="PC494_003677"
     CDS             complement(362..823)
                     /locus_tag="PC494_003677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase/bleomycin resistance/dioxygenase
                     family protein"
                     /protein_id="HDF3914107.1"
                     /translation="MKFGGVLLIVKDINKSKKFYEDVMEQKITLDLGEHVSFENGFGL
                     QSNYKAIIGYDLPIYQQSNNFQLYFEVNDIKQWESKINRIGNIEFLHYIKEYPWGQRT
                     FRFYDFDKNIIEISESMESVIKRFLKQGLALEEISKRTMYPVEFITQFQQL"
     gene            complement(861..1694)
                     /locus_tag="PC494_003678"
     CDS             complement(861..1694)
                     /locus_tag="PC494_003678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF3914108.1"
                     /translation="MLKKESIHFINKNRSLIVCEDNFVYLLPCIQLRNWISNFTISFP
                     NQTIISDNYTIIPHGSVTLVFFYDATGLHSLLFGPTTKPKTVGNIANRCDVILIIEFQ
                     PAGFFPLIGIQQSELIDKVVPFSIINTSLDLEIKKIFNESLSIDKLILKLEELLISNI
                     KIEYSYEFILAIQLIIQNSGNISSQEISKKVFYSSRHLNRLFNQYLGLSMKSFSRLVR
                     INKSIKLLNNNKTSLMSICNELGFYDIPHFIKDFKIVCGITPQKYRANMSDFYSEIAK
                     F"
BASE COUNT          646 a          269 c          212 g          696 t
ORIGIN      
        1 ttagtgtatt catgtataat aagtaaaagc acaacggtat atactgttgt gcttttttgt
       61 aattaataaa caatattttg gtctataaca atgaaaaatg gctactttcc ataattgatt
      121 tcatctgaca taagcaaaaa gggtgtccag ctgggtcaat cataactctc cagtcatcag
      181 taaattgctc ctctgcgatt gtagctccac aatgaattgc atattgaact gcttcttcta
      241 aatcattaac agcgaaatcc atatgagcca tttgctgttg agattcaggt ttttctggtt
      301 ctattatgcc ccaagccttt gttttttgca atataaagaa aaaattatat attttaatat
      361 tttataattg ttgaaattgt gtaataaatt caactggata catagtgcgt tttgaaattt
      421 cttctaaagc taaaccttgt tttaaaaacc tctttatgac gctttccata ctttctgaaa
      481 tttctataat atttttatca aaatcataaa acctaaaagt tctttgaccc catgggtatt
      541 cttttatata atgcaaaaat tcaatatttc ctattctatt tatcttactt tcccattgtt
      601 tgatgtcatt aacctcaaaa tacaactgaa agttatttga ttgttgatat attggtaaat
      661 catatccaat tatagcttta taattacttt gtaatccaaa tccattttca aatgatacat
      721 gttctcctaa atctaatgtg attttttgct ccataacatc ttcataaaac ttttttgatt
      781 tatttatgtc tttgacaatt agcaatactc ctccaaattt catcttatca ctatcctttc
      841 tttgttataa gtattataac ttaaaatttt gcaatttcac tgtaaaaatc agacatatta
      901 gctcggtatt tttgaggagt tattccacag acaattttaa aatctttaat aaaatgtggt
      961 atatcataga atcctaattc attacatata gacatcaatg aagttttatt attgtttaga
     1021 agttttatag atttattaat acgtaccaaa cgagaaaatg acttcatact caaccctagg
     1081 tactgattaa agagtctgtt taaatgccta gaactataaa atactttttt agaaatttct
     1141 tgtgaagata tatttccaga gttttgaata atcaactgaa ttgccaaaat aaactcatat
     1201 gagtattcaa ttttaatatt agaaatcaat aattcttcca actttaaaat caatttatct
     1261 atagataaag attcattaaa tattttttta atttctaaat ctaatgaagt attaattata
     1321 gaaaatggaa caactttatc aataagttca ctttgctgta tacctataag cgggaaaaaa
     1381 ccagcaggtt gaaattctat aattagtata acatcacatc tattagcaat atttcctact
     1441 gtttttggtt tagtagttgg accaaataat agactatgta accctgtggc atcataaaaa
     1501 aacaccaaag ttacacttcc atgaggaata atcgtgtaat tatcagaaat tattgtttga
     1561 tttggaaacg atatagtaaa attcgatatc caatttctta attgtataca aggcaagaga
     1621 taaacaaaat tgtcttcaca aactataagt gacctatttt tatttataaa atgaatactt
     1681 tcttttttta acatatatta tatcctgtcc tatcgtgaat atttattaaa gtaagaagaa
     1741 tccatattat ctctatatat cattaactgc ttttaataat agagatagta tgaatactca
     1801 ttagatattt aataaacaaa taa
//
LOCUS       DAMKNB010000195         1812 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.201, whole genome shotgun sequence.
ACCESSION   DAMKNB010000195 DAMKNB010000000
VERSION     DAMKNB010000195.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1812)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1812)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1812
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.201"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            206..1546
                     /locus_tag="PC494_003679"
     CDS             206..1546
                     /locus_tag="PC494_003679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HDF3914109.1"
                     /translation="MIKSSLFWNIFIAISFMIEWFLCKKMLDYTSEKRISNKKINFCM
                     VGIIVFADIIYFFDVPPNIRVIISMIITIAFYKISYDVGFIKSVLISLIYWMLLIATD
                     ALSISLTVWLNSINDMSSMGTGDIYRIESIILGKILLIVSLLLYRALKIKLNIEINKR
                     TLFYIVIPIVANIASFFVIFEYIFNPGSGSLIHNFQFVMISVVLLISSITLVLIAKKL
                     QQYNTLVVENNMIKNTLKYENEYYEDIEKKYLKTRLLSHDMKNHILCINAMIKKGIDV
                     TSYLNNLQVEIQSNDLLFNTGNFILDAILSEKKEVCDKNDIELKIGINFSCCEAVELV
                     DICHIFSNILDNAIEACNKIDSGNRVICVKGDVMQNFYLIRVENTKMNKIITKNGDIL
                     TDKKGSLHGLGIKSVKNSVNKYGGNVVIEYDDKKFVVKIAIPLRNVKKAVNHVI"
BASE COUNT          727 a          126 c          289 g          670 t
ORIGIN      
        1 aaatttatat agttattatt aaaaaaagca ataaaaagtt taattcaatt tagcaaattt
       61 agtgatataa ttaaaaaaga aaagaaatat ggacttattt ggaataattt tgacaatcta
      121 tttactacac gtgtagagtc gtatataatt aaattataca taaaatataa aaaaataatt
      181 tagtaatacg ttaggagaaa gtattatgat aaagtcaagc ttattttgga atattttcat
      241 tgcgatatcc tttatgatag aatggtttct ttgtaagaaa atgctagatt atacaagtga
      301 gaaaaggatt tctaacaaaa aaataaactt ttgtatggta ggtattattg tttttgctga
      361 cataatatat ttttttgatg tacctccaaa tataagagta attatatcta tgataattac
      421 tattgcattt tataaaatct catatgatgt ggggtttata aagtctgtat taatatcctt
      481 aatttattgg atgttactaa tcgccacaga tgctttgagt atatctttaa cagtttggct
      541 taattctata aatgacatga gtagtatggg gacgggagat atatacagaa ttgagtctat
      601 aatattggga aagatacttt tgattgtgtc tttgctttta tatagagcct taaagataaa
      661 acttaatata gaaataaata aaaggacatt attttatata gttattccta tagtcgctaa
      721 tatagcatct ttttttgtaa tttttgaata catatttaat ccagggtctg gtagcttaat
      781 acataatttc caattcgtta tgatttctgt tgtattgctt atatcaagta tcactttagt
      841 tttaattgct aaaaaattac agcaatataa tactttagtt gtagaaaaca atatgattaa
      901 aaatactttg aagtatgaaa atgagtatta tgaagatata gaaaagaaat atttaaaaac
      961 tagattacta agtcatgata tgaaaaatca catattgtgt ataaatgcta tgattaaaaa
     1021 aggtattgat gttacttctt atttaaataa tttgcaggta gaaattcaga gtaatgactt
     1081 gttatttaat actggtaatt ttatattaga tgctatatta agtgaaaaga aagaggtttg
     1141 tgataagaat gatatagaac taaaaatagg aataaatttt agttgttgtg aagctgttga
     1201 attagtggat atatgtcata tattttcaaa tattttagac aatgcaattg aggcatgtaa
     1261 taaaattgat agtggaaata gagttatttg tgttaaaggt gatgttatgc aaaattttta
     1321 tttaataaga gttgaaaata ctaagatgaa taagattatt actaaaaatg gagatatttt
     1381 gacagacaaa aaaggttctc ttcatggact tggaataaaa agtgtaaaaa actctgtaaa
     1441 taagtatggt ggtaatgttg taattgaata tgatgataaa aaatttgtag ttaaaattgc
     1501 tattccactt agaaatgtga agaaagcagt taatcatgtg atttaaatgt atataaattt
     1561 gatgtgtaga aatttaatat ataagaatta atgtataaaa gtgatgcata gaagtttaat
     1621 atataagaat taatgtataa aagtgatgta tagaagttta atatataaga atttaatatg
     1681 tataaaagtg atgcataaaa gtttaatata taggatttaa tatgtataaa agtgatgcat
     1741 aaaagtttaa tatataggaa tttagtatgt ataaaagtga tgcatagaaa tttaatatat
     1801 aagaatttaa ta
//
LOCUS       DAMKNB010000196         1791 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.202, whole genome shotgun sequence.
ACCESSION   DAMKNB010000196 DAMKNB010000000
VERSION     DAMKNB010000196.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1791)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1791)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1791
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.202"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            complement(792..1109)
                     /locus_tag="PC494_003680"
     CDS             complement(792..1109)
                     /locus_tag="PC494_003680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3914110.1"
                     /translation="MNFRNIYLILMGLGIIILTTIISLIEIKIGFCNEKYFNKLESKY
                     GNIDRKRTIKLEVLYRYVTGFEYIAIGLFTKRLDITIIAIILVATITVILYYLVRKRY
                     ITI"
     gene            complement(1419..1787)
                     /locus_tag="PC494_003681"
                     /pseudo
     CDS             complement(1419..1787)
                     /locus_tag="PC494_003681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889008.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT          641 a          226 c          180 g          744 t
ORIGIN      
        1 tttttggaaa ttatatatat tataacaatt atagcaaatt tttagggtat aatttttaaa
       61 attatattct actatcaaaa gatatgaata aatgattgta tatattatat caatttttat
      121 atttcatagt ccattttttc atcacatttt cgcttgtcaa gaataatatc tttaagagtg
      181 aagcgtttga tgtaaatctg gactttgttt ttgagacatt tttgaaatat ttattaaatc
      241 tttcgattat acttgtaata tatattatag atattactta ttttagtaaa actaaaggat
      301 gatgctacaa cattccagtt atttcccaaa attttaattt ctgaagtata ctgtttacat
      361 tatttttaat ctattttatc taaagtcgat aaggcttctt attcattaac tgacctatat
      421 acagatttaa aattacttat taattctttt gagtccttgt atgaaacata tttaaagtat
      481 ttcttatcta atgtattaaa catttttgta ttacagaatg aggataactt gtagctattg
      541 tctctttgaa ataagtcatc tgtgtttact cctaaaacta cttatatctg tagattttat
      601 aagttctcca tcttatataa tttctttgat taattgtttt cttaaattat tcataaaaaa
      661 atctccgtta caatatttga ttatatttaa atcattgcta taaagaagac ttttattaac
      721 tttgaaaaac aaattatttt aattgctggt gattagttgc taccttcttt tgatattaat
      781 tctattagat tttatatagt tatatatctc tttctaacta agtaatataa tattactgtt
      841 atagtagcta ctaatattat tgctattatt gtaatatcta atctttttgt aaataatcct
      901 attgctatat attcaaaacc tgttacatat cgataaagta cttctagttt aatagttctt
      961 tttctatcta tatttccata ttttgattct aatttattaa aatatttttc attacaaaaa
     1021 ccaattttaa tttcaattaa agatattatt gtagttaata ttataattcc caatcccata
     1081 agtataagat aaatgttcct aaaattcata gaagatacct cctttataat ataatcatca
     1141 actcatgttg tattaatttt cctaatcaaa gtataacagt aacacaagta taaagagtat
     1201 ctaaaatatt acaaatatta aatgagaaaa agatggtaag ttaaccccac catcttattt
     1261 tttatctact aatgaatgat gctacaaaag ttagtataaa aaatgaaaca aacaatataa
     1321 tgaacttgtg taatttactt agttggaatg ctttattaca aaataataaa attaatgctg
     1381 aaacaattgc aaaaagtaga tattttataa tcattttatc acctattgat ttctacagat
     1441 tgtaagtagt atttggttac acaagcacct cctttattat aacgtatttt ttaaatttaa
     1501 agatttttcc agatgttata tttgactcaa ggtacattgt aattaatcta actataagtg
     1561 gcaagtactg tcctatacca ggaatagcac cagccaaaag tcctgaaatc cctataccag
     1621 catcagttaa agttaatgca actcctttag aaagatataa attaaaacct attctagccc
     1681 aaactatttt atttatttca gcttttctat aatataattc aagtagtgtc aatatcgttc
     1741 ttcttaaggt ttttaattag cttatatatt gttattgtat aatataatta t
//
LOCUS       DAMKNB010000197         1600 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.203, whole genome shotgun sequence.
ACCESSION   DAMKNB010000197 DAMKNB010000000
VERSION     DAMKNB010000197.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1600)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1600)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1600
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.203"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            84..1556
                     /locus_tag="PC494_003682"
     CDS             84..1556
                     /locus_tag="PC494_003682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp28"
                     /protein_id="HDF3914111.1"
                     /translation="MKFYKRILTLTLSISFVFANIQLVDAISSVEKIQGKNKYEIAGK
                     IADKNAYKTAYKTAYKTAYKTAILINTSNSIADGLSASGLAGALNAPILLTEKNTIPT
                     ETSARLKNVSKVYIIGGTYSISTSVENSLKSKKMKVVRIKGNDRIKTSYNVAKEINSI
                     KKVNTVMLTNAYKGEADAISIASVAARDKAPIILTNGQSIPFSTSGLKSYVIGGTASM
                     STTLVNNTKSTRLGGSTRFETNKAIINKFYKDAREFYIAGAYELTNALVGSSLSKHGP
                     MVLVNDGSNKSILKNAKKITSIGYIDSNIVQQCLNITNGIGDINTGVVKNVKPTTKTI
                     KDGMYKVGKDISAGEYLITSNSGSYASYYEVTSDSTGNADSILSNDIFSGTRYITLKN
                     GQYIKIEDSTMTLAKYAKAQKAKNGKFGNGMYKIGLEIPAGEYIIMSNSSDAYYEVRN
                     DSLGNAEGIVTNDTFSGRRYITVEEDQYLILNDCYLIENE"
BASE COUNT          661 a          169 c          271 g          499 t
ORIGIN      
        1 tacataagtt tgttaagtac ataactaatt taagaatatg tatttatata ttaaaaattt
       61 attatgaggg ggacaatttt attatgaaat tctataaaag aatattaaca ttgactttaa
      121 gtatttcttt tgtatttgca aatattcaat tagtagatgc aatatcatct gtagaaaaaa
      181 tacaaggaaa aaataagtat gaaatagcag gtaaaatagc agataaaaat gcatataaaa
      241 ctgcatataa aactgcatat aaaactgcat ataaaactgc tatattaatt aatactagta
      301 actctattgc agatggatta agtgcaagtg gactagcagg agctttaaat gcccctatac
      361 tattaactga aaaaaatact ataccaactg agacatctgc aagattaaaa aatgtatcaa
      421 aagtttatat aattggagga acatattcta ttagtacatc tgtcgaaaat tcattaaaat
      481 ctaagaaaat gaaagttgta agaattaagg gaaatgacag aataaaaaca agttataatg
      541 ttgcaaaaga aataaattca ataaaaaaag tcaatactgt tatgctaacc aatgcatata
      601 aaggagaagc agatgctata agtattgcat ctgtagcagc aagagataaa gcaccaataa
      661 ttcttactaa tggacaaagt ataccttttt caactagtgg tttaaagtct tatgtaatag
      721 gaggaacagc ttcaatgagt accactttag taaacaatac taaatctact agactagggg
      781 ggagtactcg ttttgaaact aataaagcaa taataaataa gttttataag gatgctagag
      841 agttttatat agctggagct tatgaattaa caaatgcact tgtaggatct tctttatcaa
      901 aacatggtcc aatggtttta gttaacgatg gtagcaataa aagcatttta aaaaatgcta
      961 agaagataac ttctatagga tatatagatt caaatatagt acaacagtgt ttaaatataa
     1021 caaatggaat tggagatatt aatactgggg ttgtaaaaaa tgttaaacct actacaaaga
     1081 ctataaaaga tggaatgtat aaggttggaa aagatatctc agcaggtgaa tacttaataa
     1141 cttcaaactc aggaagttat gcttcttatt atgaagttac aagtgatagt acaggtaatg
     1201 ctgatagtat actttcaaat gatattttta gtgggactag atatatcacc ttaaagaatg
     1261 gtcaatatat taaaattgag gattcaacaa tgacattagc aaagtatgct aaagcccaga
     1321 aggccaagaa tggtaagttt ggaaatggta tgtataaaat tggattagaa attcctgctg
     1381 gagaatatat tataatgtca aattcttctg atgcatatta tgaagttaga aatgatagct
     1441 taggtaatgc agagggaata gttactaatg atactttttc aggaagaaga tatataacgg
     1501 ttgaggaaga tcaatattta atattaaatg attgttattt aattgaaaat gaatagatgt
     1561 aattgtattt aatagtaaat catatatttt atttaaggaa
//
LOCUS       DAMKNB010000198         1576 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.204, whole genome shotgun sequence.
ACCESSION   DAMKNB010000198 DAMKNB010000000
VERSION     DAMKNB010000198.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1576)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1576)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1576
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.204"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            1042..1431
                     /locus_tag="PC494_003683"
     CDS             1042..1431
                     /locus_tag="PC494_003683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HDF3914112.1"
                     /translation="MTIKKLPQSELKIMKFIWKSDSKVTSRDIVLGMEQKYQWKQTTT
                     LTLLSRLVVKRFLNSQKIDKYTHYEVLIKEKEYIGVETRDFFRNIHDSSIKSLLLSLH
                     ENINLSKDDILLIEEWIKNLKEEEKDV"
BASE COUNT          688 a           89 c          290 g          509 t
ORIGIN      
        1 aaataaaaaa actctaaaat agaaggatat aattatatag aatgtttcaa ttaaacaagg
       61 taaaaactat aatcttaaaa ttaaaattaa cattattctt aagaagcaag aaatttagaa
      121 agtaggaagt ttagtgataa gtggtagtaa gtaagaaatt taggaagtgg gaagtttagt
      181 gataagtggt agtaagtaag aaatttagga agtgggaagt ttagttataa gtggtagtaa
      241 gtaagaaatt taggaagtgg gaagtttagt tataagtagt agtaagtaag aaacttagga
      301 agtgggaagt ttattagtaa taatttatag caagtaagaa atttagtaat aatttgtagc
      361 aagtaagaaa tttagaaagt aggaagttta gtaataattt atagcaagta agaaatttag
      421 ggagtaggaa gtttagtaat aatttgtggt aagtaagaaa tttagaaagt aggaagttta
      481 gtaataattt atagtaagta agaaatttag taagtgggaa gtttagtagt aataatttat
      541 agtaagtaag aaatttagaa agtaggaagt ttagtaataa tttatagtaa gtaagaaatt
      601 tagaaagtag gaagtttagt aataatttat agtaagtaag aaatttagta agtgagaagt
      661 tcagtaataa gttgtagtaa ataaaaagtt taggaagtag gaagttcagt aataagttgt
      721 agtaaataaa aaatttagga agtaggattt actgaaatac aaatatttaa aatcaaagag
      781 tttaaaagaa aggagagcta ctggacaagt atccaaaata gatagctgag tacaaaatat
      841 ttcataaaat taagcaatat aatacaagag aattttgaca ttatttatat atatttaccg
      901 tgtacaaata gctaaattta ggattaagat tgaaaaatat cttataagtc tgagcttata
      961 taaatccgta taagatgtat ttaatcgaaa aattttatta tggatattgc ttgtctatat
     1021 tctgagtagc aaggttttat catgactata aaaaagttgc cacaatcaga attaaagata
     1081 atgaaattta tatggaaatc agattccaaa gtaacatcta gagatattgt tttaggaatg
     1141 gagcaaaaat atcaatggaa acaaacgaca actttgactc ttttatctag attagtagta
     1201 aaaagatttc taaattctca aaagatagat aaatatacgc attatgaagt tttaattaaa
     1261 gaaaaggaat acataggagt tgagacaaga gattttttta gaaatattca tgattcttct
     1321 ataaaaagtt tattgttgtc attacatgaa aatattaatt tgagcaaaga tgatatttta
     1381 cttattgaag agtggataaa aaatctaaaa gaagaggaga aagacgtata agcaaacgta
     1441 tttcttatag catcaatata aagtgtatgt aagtgtattt atgtaatata ttagtctact
     1501 taagtaatat gacaaatgat tataagtgga ttatgatact ataatgtgaa tctaaataaa
     1561 ttaaatataa attaat
//
LOCUS       DAMKNB010000199         1556 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.205, whole genome shotgun sequence.
ACCESSION   DAMKNB010000199 DAMKNB010000000
VERSION     DAMKNB010000199.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1556)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1556)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1556
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.205"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            498..1205
                     /locus_tag="PC494_003684"
     CDS             498..1205
                     /locus_tag="PC494_003684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HDF3914113.1"
                     /translation="MIFTKSNKYDKDFLMKNMMGPNCIKILEELTSKIKLEKGMRILD
                     LGCGKGISSIFLAKEFDATVFATDLWIEPTENYKRFKEFKLDDKIFPIQAEAHELPYA
                     EGFFDAVISIDSYHYFGNKEGFLDNHISPLVKEGGILAMAMPGLKEDFVDCIPDELIP
                     FWQDNMNFHSITWWNKLWSESESVIVEKCEALNCHDEAWKDWINCDNSYAINDKKMME
                     VENGKYFNTISLIARTK"
BASE COUNT          653 a          136 c          273 g          494 t
ORIGIN      
        1 taaatggtat aataaaaggt aaagtgtcaa atatgcacta aattaaataa gttaattagt
       61 atataggtta aagtggaagt aattaaaact tattaagtat tagaaaatga cttcttatta
      121 gagtaagtat ctaaaatgat ataaaaatta tgattactca ttaaagtgac tattatagag
      181 tggataagat tactcattaa agcgattact gtggagtaga taaaattact cactaaaata
      241 actatcatag agtggataag attactcatt aaagcgattg ctgtggagta gataaaatta
      301 ctcactaaaa taactatcac agtagataag attattcatt aaagttacta tcacagagtg
      361 gataaaatta cacattaaaa ttgtctgtta aagaatgaat aaaaaagaga ttgctcaata
      421 taagaagcat ataaaaaata aaaaatcaaa cgtataaaat ttaataaata ataactgata
      481 gggaaaggaa agatagaatg atatttacaa aaagtaataa atacgataag gactttctca
      541 tgaaaaatat gatgggacct aattgtataa aaatattgga agaattaaca agtaagataa
      601 aactagaaaa gggaatgcgt attttagact taggttgtgg taaaggtata tcttcgatat
      661 ttttagcaaa ggaatttgat gctactgtat ttgcaacaga tttatggata gaaccaactg
      721 aaaactataa aagatttaaa gagtttaaat tggatgataa aatatttcca atacaggcag
      781 aggcacatga actaccttat gcagaaggtt tctttgatgc ggtgataagt atcgattctt
      841 atcactattt tggaaacaaa gaaggatttt tagacaatca tatatcacct cttgtaaaag
      901 aggggggaat acttgctatg gcaatgcctg gattaaaaga agatttcgtg gattgtatac
      961 cagatgaact cattccattt tggcaagata atatgaactt ccattcaatt acatggtgga
     1021 ataaactttg gtctgaatcg gagtctgtga ttgtagagaa atgtgaagct ttaaattgtc
     1081 atgatgaagc ttggaaggat tggataaatt gtgataattc atatgctata aatgacaaaa
     1141 aaatgatgga agtagagaat ggaaagtatt ttaatacaat ttctttgata gcgagaacta
     1201 aataattgtg atgaatttat aaaagtataa gaagcataga aatataagtt gaatgagagt
     1261 ataagaagca tagaaatata agttgaatta aagtagaagg taaataaaaa tgtaagttaa
     1321 ataaagagtt tatacaaaaa tgatttttta gattatttat acccaatcga gttgcttagg
     1381 tcagttgggt atttttattt tttaaagtta aattgcaaat actattgtgt gatatatatt
     1441 ttaatactaa atgtttgttt tataagaaat aaactaatag aaaaaatagt tttaacaatg
     1501 aaagcaaaaa aggtattgat gaagattaaa aattttatag taccatttta tatatt
//
LOCUS       DAMKNB010000200         1464 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.206, whole genome shotgun sequence.
ACCESSION   DAMKNB010000200 DAMKNB010000000
VERSION     DAMKNB010000200.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1464)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1464)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1464
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.206"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     repeat_region   15..972
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=82..110
                     /rpt_unit_seq="atttacattccatatagttaatataaaac"
BASE COUNT          589 a          187 c          155 g          533 t
ORIGIN      
        1 agaaaattat aaaaacttac attctgtata gttaatataa aacataagta atataaattt
       61 atgtaaagca acaaaagatg gatttacatt ccatatagtt aatataaaac gatttcaaat
      121 gattagaata aaaatatcag aattgctatt tatattccat atagttaata taaaactcaa
      181 acatatctaa gttgtatttc tcaccttgta ggtcatttac attccatata gttaatataa
      241 aacaaggatt ttgaatgtaa tttatcataa gggtggcaga tttacattcc atatagttaa
      301 tataaaacat gaaagataat tggaaaacta aagtgcaatc taaaaaattt acattccata
      361 tagttaatat aaaacggaga attattaaaa ggagttcccg aagcagatag aataatttac
      421 attccatata gttaatataa aaccattgtt attattgtgg ttctccctta gctcataatt
      481 tatttacatt ccatatagtt aatataaaac atgatattat tataatatta taaatataat
      541 aatgaggatt tacattccat atagttaata taaaactaga tatttaaaat aagcgaaagg
      601 gggtcataaa aatatttaca ttccatatag ttaatataaa acattctaaa gatattttgc
      661 cttgcagttg ggatttcgaa tttacattcc atatagttaa tataaaacca tcataggggc
      721 taatatagtt aaaggtgttg gcgtatttac attccatata gttaatataa aacggtttgg
      781 ttacaaggta tagtagaagg atatagtgga atttacattc catatagtta atataaaaca
      841 tggaactaag agagtacacc atcacatgat actcaaattt acattccata tagttaatat
      901 aaaactaaag ctggaaaaga aacagctata atgagtaata ataatttaca ttccatatag
      961 ttaatataaa accccaaaat aaacttagta ttttcaatac ttacacgtat acaactctct
     1021 taaatttgca gtgaacgagc aatagtgcaa ttgataacgc ttatcataca ctctcaacgc
     1081 cttatatttc aactgttacg ccaaattttt tcacaaatat cgctcactgc aaaattccta
     1141 taattttatt atatcataaa tatattactt ttgaatattg atactaattt ataccataat
     1201 aaaagcaaaa aaacgtaatc tatctacatt agatttaaat tctataactt aaagtttttt
     1261 acataatatt tatgcttgtt taatcaatct aatatatcat tcttgtatat tgcttttaat
     1321 agtctttttt cttaaataaa tatctatctg aacaagcata gtttaattaa aaacttttgt
     1381 attcccttaa aactgtatct acctcttatt attttattta tgatatatta tttttaatct
     1441 aaaaatagat atctattttt atta
//
LOCUS       DAMKNB010000201         1454 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.207, whole genome shotgun sequence.
ACCESSION   DAMKNB010000201 DAMKNB010000000
VERSION     DAMKNB010000201.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1454)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1454)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1454
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.207"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            complement(284..595)
                     /locus_tag="PC494_003685"
     CDS             complement(284..595)
                     /locus_tag="PC494_003685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3914114.1"
                     /translation="MKKIIKSFTFWFFLIALFEIYMHQIGQDSKSIVLIGLNPILSII
                     SRVDSFFVFMDSGMQIPCRTITGSISIYWYIASILSFLIYGIILDLIRIVISKIGNKT
                     K"
     gene            complement(651..1244)
                     /locus_tag="PC494_003686"
     CDS             complement(651..1244)
                     /locus_tag="PC494_003686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HDF3914115.1"
                     /translation="MISDSISKRRSIRKYKNQSISHETIEKIIEAGINAPSSKNRQPW
                     RFVVITEKEKESMLKAMSKGIQNEINDNGLLPGSRQHIAGANYTVEIMKQAPVTIFIL
                     NILGKSPLEKLSPEERFYEMANMQSIGAAIQNMSLTAVELGLGSLWICDVYFAYRELC
                     EWLNTDSQLVAAISLGYPDEEPSRRPRLQLSDVTEWR"
BASE COUNT          529 a          200 c          189 g          536 t
ORIGIN      
        1 aggaagtata gaaagctaat ctaaagaagt atagtaaact aatttaggaa gtatagaaaa
       61 ttaatctaaa gaagtataat aaactaattt aagaaatata gaaaattaat ttaaagaaat
      121 acaatacatt aatttttaag taacattaaa ttaatgtaag taaaataatg ttcatatgaa
      181 gatttaaagg tgcattttct gaagctaagt atatgttgta gagtgttagg tctctctatc
      241 ctgtgaagtt taatagctca agaaaatgca ctatttatga tgattatttt gttttatttc
      301 caattttgga aataactatt ctaattaaat ctaaaattat accataaata agaaaagaaa
      361 gtatagatgc tatgtaccaa taaatcgaaa ttgaccctgt aattgttcta catgggattt
      421 gcatacctga atccataaaa acaaaaaaac tatcaactct ggaaataata gacaaaatag
      481 gatttaaacc tattagaaca atactttttg agtcttgacc aatttgatgc atataaatct
      541 caaataatgc aattaaaaaa aaccaaaatg taaaagattt aataattttt ttcatcaaaa
      601 tacctcacat aatataaatt ctgtttgcac tatttgctta ctacaactat ttatctccat
      661 tcagtcacat cacttaattg taatctaggt cttcttgatg gttcttcatc aggataaccc
      721 aaagatattg ctgccactaa ttgactatct gtatttaacc attcacataa ttcacgatat
      781 gcaaagtata catcacaaat ccaaagacta cctagaccta attccacagc tgtaagcgac
      841 atattctgaa ttgcagctcc aattgattgc atgtttgcca tttcatagaa tcgttcttca
      901 ggggatagct tttctaaagg tgatttacct aatatattta aaataaaaat tgttactgga
      961 gcttgtttca tgatttcaac tgtgtaattt gcaccagcga tatgttgacg acttcctgga
     1021 agaagcccat tatcattaat ttcattttga atacctttgc tcatggcttt aagcatagat
     1081 tctttttcct tttcagtgat gacaacaaaa cgccatggtt gcctgttttt agatgaaggt
     1141 gcatttattc cagcttcaat tattttctct atagtttcat gtgaaatgct ttgattttta
     1201 tattttctga tacttcgtct ttttgatata gaatcactta tcattttaag taacctccgt
     1261 ttattttttg gaaaaatcta tttaattttt attttctatt ttaattattt tagcattaat
     1321 cagaaaaaaa gtcattgatt ttagtataca attattaatg attatattaa gaattgtatc
     1381 aaaaagtatg tgattatact aagggattat attaaacatt atatttaaaa ttgtatgaaa
     1441 ggttgtattt aata
//
LOCUS       DAMKNB010000202         1369 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.208, whole genome shotgun sequence.
ACCESSION   DAMKNB010000202 DAMKNB010000000
VERSION     DAMKNB010000202.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1369)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1369)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1369
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.208"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            165..542
                     /locus_tag="PC494_003687"
     CDS             165..542
                     /locus_tag="PC494_003687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HDF3914116.1"
                     /translation="MTITKIPPAELKVMKFIWSSDFTVASKDVIEAMEKLYNWKQTTT
                     LTLLSRLVNKQFLSARKIDRHTHYTVLIGEEEYLHFETKTFLDNMHGSSIESFMKSLF
                     KKGVNEEELNSVEKWVKDIKKDE"
     gene            complement(979..1242)
                     /locus_tag="PC494_003688"
     CDS             complement(979..1242)
                     /locus_tag="PC494_003688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3914117.1"
                     /translation="MIKNTKQITVEVNEILLQEMSKITNDENNILTDLINESIVNYIL
                     ENKKHNIENKDLEEVIKFYKKENTEKPKSAARAIAEAKTHTLY"
BASE COUNT          515 a          113 c          178 g          563 t
ORIGIN      
        1 tatttatctt tatattaata gattgtgtgt ttaattttga ataaaaatat aaattttttg
       61 tattaataaa tttggatgag atattttaaa taaaaccttt gactcgaaaa gtctattaat
      121 atagtattta attatgtaga agtttgagag gagtgtaaaa tcatatgact attactaaga
      181 taccaccagc agaattaaaa gtcatgaaat ttatttggag ttcagatttt acagtagcat
      241 caaaagatgt cattgaagct atggaaaaac tatataattg gaagcaaact acaacactaa
      301 cacttttatc aagattagta aataagcaat tcttaagtgc aagaaaaatt gatagacata
      361 cacattatac agttcttatt ggagaagaag agtatttaca ttttgaaaca aaaacttttt
      421 tagataatat gcatggaagt tctattgaga gttttatgaa atccttgttc aaaaaggggg
      481 taaatgaaga agaattgaac tctgttgaaa aatgggttaa ggatattaaa aaagatgaat
      541 aatttggtgt agttaattat cataaaataa atagttttta caataattag ttaaatgaat
      601 caaatataaa gttttatgta aaatttgtga tttttataaa tatttttgtc ttgttattta
      661 atattaatac aataagtttg atgtaaaatc aaacctgttt gaatttaatt tatattgggt
      721 ttgtcattaa tattatttta gtttgatatt gtatacgaat ttaaaagtca gaatttttgt
      781 atattaatca tgtaaattaa ttgttttaga tataaagggc ataattttat ttttgttttg
      841 attatttcta gggtaagata agtatacaat agattgtatt aaacatgctt atattgatag
      901 atttgagata aatattgaga tatattaata attattaata taaaaaagtt cctagttttt
      961 aggaactttt ttatttgatt aatacagagt atgagttttt gcttcagcta tagctcttgc
     1021 tgcactttta ggtttttcag tattttcttt tttgtaaaat ttaatcactt cttctaaatc
     1081 tttattttca atattatgtt ttttgttttc aagaatataa tttacaattg attcatttat
     1141 caaatctgtc aaaatattat tttcgtcatt agttatctta gacatttctt gtaataaaat
     1201 ttcattaact tctactgtaa tttgttttgt attttttatc atatcaacca cctcttaaga
     1261 aaattatatc atctcaaaaa aataaattca atatgtttta aaattataga attttaattc
     1321 ttaaattcta aaaaagagaa aattagataa agtagtttta gattttaaa
//
LOCUS       DAMKNB010000203         1342 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.209, whole genome shotgun sequence.
ACCESSION   DAMKNB010000203 DAMKNB010000000
VERSION     DAMKNB010000203.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1342)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1342)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1342
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.209"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            6..473
                     /locus_tag="PC494_003689"
     CDS             6..473
                     /locus_tag="PC494_003689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2975 domain-containing protein"
                     /protein_id="HDF3914118.1"
                     /translation="MITKFFSNILSVFLYFLLSLLGVAGIIFLCMIPMFLYDFSSDKV
                     IALIARILYFSDYFIVILFLIFIINSTKYSPFVLENVKRFKVMGCCLLINTIIECING
                     YNLNTNNIRIFGTDSGGISPLMVISFIFALMCFVIAETFDKAIKIKEDNDLTI"
     gene            484..699
                     /locus_tag="PC494_003690"
     CDS             484..699
                     /locus_tag="PC494_003690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF3914119.1"
                     /translation="MAIVVNLDVMMAKRKISLKDLAEKIDITNANLSILKTGKAKAIR
                     FTTLNEICKALDCQPGDILEYVEDEND"
     gene            1140..1313
                     /locus_tag="PC494_003691"
     CDS             1140..1313
                     /locus_tag="PC494_003691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="succinate dehydrogenase"
                     /protein_id="HDF3914120.1"
                     /translation="MKRKLSTYFKGYILGLCIAFLLFTFILKKLIIENIIGIIIGTGI
                     AFLLIYLFNKKRK"
BASE COUNT          494 a          149 c          167 g          532 t
ORIGIN      
        1 attttatgat tacaaaattt tttagtaata tattatcagt atttctatat tttctattat
       61 cacttttagg agttgctggt ataatattct tatgtatgat acctatgttt ttatatgatt
      121 ttagttctga caaagtaatc gctttaattg caagaatact atatttttct gactacttta
      181 tagtcatctt attcttgata tttataatta atagtactaa gtattcccca ttcgtacttg
      241 aaaatgtaaa aaggtttaag gtaatgggat gttgtttatt gataaacact ataattgaat
      301 gtataaatgg ttataattta aatactaata atataagaat ttttggaact gatagtggcg
      361 gtatctcacc acttatggtt atctctttta tatttgcact aatgtgcttt gtaattgcag
      421 aaacatttga taaagctata aaaataaaag aagataatga tttaacaata tagaggtgat
      481 gttatggcaa tagtagttaa cctagatgta atgatggcaa aaaggaaaat atcacttaaa
      541 gatttggcag aaaaaataga tattacaaat gcaaatttat caattttaaa aactggaaaa
      601 gcaaaagcta ttagatttac cactctaaac gaaatttgca aagctttaga ctgtcagcca
      661 ggtgatatac ttgaatatgt agaagatgaa aatgattaaa aaagagtgtt tagaaacact
      721 cttttttatt atactatatg atttttattc ttttactata ttattgacat taatattaac
      781 tttgtttaaa gtcataacaa aatatgttct aagaaagaaa ctgttccttt atctatttgt
      841 tatccattac ctataagaac tgtatcacac taaatcatac ttttaaattg ataattttac
      901 cacagattcc tatatacatt cttttctacc taatatttgt ttaaactgtt agcaaaacat
      961 ggaacttttt catttactta tacctccatt tatattattg catagtttat agctacgtgt
     1021 tataaattac attattgatg attttatcta acatttgtaa tcttttagat actctttgaa
     1081 gttacaacac tgttatactc taattaagta aactaaatct gatacaagtt ggtgattata
     1141 tgaaaagaaa actttcaacc tattttaaag gatatatttt aggtttatgt atagcatttt
     1201 tattatttac ttttatatta aaaaaattaa ttatagaaaa tatcattgga ataataattg
     1261 gaactggaat tgcattttta ctgatttacc tatttaataa aaaaagaaaa taatattcta
     1321 taaaaaggtc ttttagtgaa tt
//
LOCUS       DAMKNB010000204         1336 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.210, whole genome shotgun sequence.
ACCESSION   DAMKNB010000204 DAMKNB010000000
VERSION     DAMKNB010000204.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1336)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1336)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1336
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.210"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            27..101
                     /locus_tag="PC494_003692"
     tRNA            27..101
                     /locus_tag="PC494_003692"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:59..61,aa:Thr,seq:tgt)
     gene            116..200
                     /locus_tag="PC494_003693"
     tRNA            116..200
                     /locus_tag="PC494_003693"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:150..152,aa:Tyr,seq:gta)
     gene            210..293
                     /locus_tag="PC494_003694"
     tRNA            210..293
                     /locus_tag="PC494_003694"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:244..246,aa:Leu,seq:tag)
     gene            323..399
                     /locus_tag="PC494_003695"
     tRNA            323..399
                     /locus_tag="PC494_003695"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:357..359,aa:Arg,seq:tct)
     gene            407..482
                     /locus_tag="PC494_003696"
     tRNA            407..482
                     /locus_tag="PC494_003696"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:440..442,aa:Gln,seq:ttg)
     gene            570..658
                     /locus_tag="PC494_003697"
     tRNA            570..658
                     /locus_tag="PC494_003697"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:604..606,aa:Ser,seq:tga)
     gene            662..737
                     /locus_tag="PC494_003698"
     tRNA            662..737
                     /locus_tag="PC494_003698"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:695..697,aa:Phe,seq:gaa)
     gene            744..817
                     /locus_tag="PC494_003699"
     tRNA            744..817
                     /locus_tag="PC494_003699"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:778..780,aa:Met,seq:cat)
     gene            832..908
                     /locus_tag="PC494_003700"
     tRNA            832..908
                     /locus_tag="PC494_003700"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:866..868,aa:Ile,seq:cat)
     gene            932..1008
                     /locus_tag="PC494_003701"
     tRNA            932..1008
                     /locus_tag="PC494_003701"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:966..968,aa:Pro,seq:tgg)
     gene            1016..1092
                     /locus_tag="PC494_003702"
     tRNA            1016..1092
                     /locus_tag="PC494_003702"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1050..1052,aa:His,seq:gtg)
     gene            1101..1176
                     /locus_tag="PC494_003703"
     tRNA            1101..1176
                     /locus_tag="PC494_003703"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1134..1136,aa:Lys,seq:ttt)
     gene            1184..1257
                     /locus_tag="PC494_003704"
     tRNA            1184..1257
                     /locus_tag="PC494_003704"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1216..1218,aa:Cys,seq:gca)
     gene            1264..1335
                     /locus_tag="PC494_003705"
     tRNA            1264..1335
                     /locus_tag="PC494_003705"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1296..1298,aa:Asn,seq:gtt)
BASE COUNT          321 a          309 c          355 g          351 t
ORIGIN      
        1 ccccttccag gtcgccaaaa taaaatgctg gtgtggctca acggtagagc agctgacttg
       61 taatcagcag gttgtaggtt cgattcctat caccagctcc atgtaaaatt aatacggagg
      121 atttcccgag cggccaaagg gggcagactg taaatctgtt gtcatcgact tcggtggttc
      181 gaatccacca tcctccacca aaaaaatgcg cggatgtggc ggaattggca gacgcactag
      241 acttaggatc tagcgccatt ggcgtggggg ttcgactccc ttcatccgca ccatttttgt
      301 ttgatataca tatataaatt gtgggtgcat agctcagctg gatagagcaa cgcccttcta
      361 aggcgtgtgt ccggggttcg aatccctgtg cgctcaccac atatattggg gattagccaa
      421 gtcggtaagg cacatgactt tgactcatgt atgcgtaggt tcgagtcctg catccccagc
      481 caaatgatgt attactaagc tatatttgaa ttattttatt ttaaatatag ttaggttcaa
      541 ttttagaata agtttaagta tccgaatgtg gagaggtgtc cgagtggttt aaggagctgg
      601 tcttgaaaac cagtgacttc gaaaggggcc gtgggttcga atcccaccct ctccgccaaa
      661 tgcccagata gctcagtcgg tagagcaggg gactgaaaat ccccgtgtcg gtggttcgat
      721 tccgcctctg ggcaccaaaa tatggcggta tagcttagtt ggctagagcg ttcggttcat
      781 acccgaaagg tcataggttc gactcctatt accgctacta aaatttaatg tgggccatta
      841 gctcagttgg ttagagcgcc cggctcataa ccggtaggtc tggggttcga gtccctgatg
      901 gcccaccaca ttaaattaat taatataaat tcgaggtgta gcgcagtttg gtagcgcaca
      961 tggtttggga ccatggggcc gggggttcga gtcccttcac ctcgaccaat ataaggtggg
     1021 tatagctcag ttggttagag cgccagattg tggctctgga ggtcgtgagt tcgactctca
     1081 ttatccaccc caattcatat ggtctattag ctcagtcggt agagcacctg acttttaatc
     1141 agggtgtccc gcgttcgagt cgcggataga tcaccaaaaa ggtggcgaca tagccaagtg
     1201 gtaaggcagt ggactgcaac tccttgatcc ccagttcgaa tctgggtgtc gcctccaaaa
     1261 tattccaagg tagctcaacg gtggagcaac cggctgttaa ccggtaggct gtgggttcga
     1321 gccccaccct tggagc
//
LOCUS       DAMKNB010000205         1239 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.211, whole genome shotgun sequence.
ACCESSION   DAMKNB010000205 DAMKNB010000000
VERSION     DAMKNB010000205.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1239)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1239)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1239
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.211"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            116..1156
                     /locus_tag="PC494_003706"
     CDS             116..1156
                     /locus_tag="PC494_003706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HDF3914121.1"
                     /translation="MNLNLTNTINLMKKYLDIPSPAGYTENAVLEIKKDFENLGLDTI
                     LTKKGALIATLPGEDDSNQITISAHMDTLGAIVKEISSDGTLKYHKVGGGCWAAIEGE
                     NCTVITRKGKKIRGSVVFKYASTHIYGQTKAATERNEETMIIRLDEKVFTKQDVLDLG
                     ISVGDFVCLDHRFEATESGFIKSRYIDNKSAVAMVLEICRYFKENNLTPKHTTNFYIS
                     NYEEIGHGVSKCLPEKTKEFVAIDIAPTGPSQTSSEHGVTIVAKDNLSLYDFNLRNKL
                     VDVAEDNNLDYAVDVFTFYGSDASEAIRWGEDVQIACVGPGTNNSHHYERTHIEAIEN
                     TLKLLINYMLKE"
BASE COUNT          474 a          144 c          198 g          423 t
ORIGIN      
        1 ttttatatac ttttttttta aatatgttta gattctattc ttttaatttt agttttcaga
       61 acatttgtat ttatgttata atttgtataa atatatttat ttaggaggaa acaatatgaa
      121 tttaaattta actaatacta taaatttaat gaaaaaatat ttggacattc caagcccagc
      181 tggatatact gaaaatgcag ttttagaaat caaaaaagat tttgaaaatt taggtcttga
      241 cactattctt acaaaaaaag gtgcacttat agctactctt cctggtgaag atgattcaaa
      301 tcaaataaca atatctgcac atatggatac acttggagct atagtaaaag aaatatcatc
      361 tgatggtact cttaaatacc ataaagttgg tggtggatgt tgggcggcta tagagggaga
      421 aaactgtact gttataacta gaaaaggtaa aaaaatcaga ggaagtgttg tatttaagta
      481 tgcttctact catatatatg gtcaaacaaa agctgccact gaaagaaatg aagaaacaat
      541 gattattaga cttgatgaaa aagtatttac aaagcaagat gtattagatt taggaataag
      601 tgttggggat tttgtatgcc tagaccatag atttgaggct acagaatctg gttttataaa
      661 atctagatat atagataata aatcagctgt agcaatggtt cttgaaatat gtagatattt
      721 taaagaaaac aatttaacac ctaagcatac tactaacttt tatataagta attatgaaga
      781 aattggacat ggtgtttcta aatgtttacc tgaaaaaaca aaagaatttg tagcaataga
      841 tatagcacct actggaccaa gtcaaacatc tagtgaacat ggtgtaacta tagttgcaaa
      901 agataattta tcattatatg attttaattt aagaaacaag cttgtcgatg ttgcagaaga
      961 caataattta gactacgctg tcgatgtatt tactttctat ggttcagatg cttcagaagc
     1021 tattcgttgg ggagaagatg ttcaaatagc atgtgttggt cctggaacaa acaatagtca
     1081 ccattatgaa agaacacata tagaagctat tgaaaataca ctaaaattac ttataaatta
     1141 tatgcttaaa gaataattaa ttatatattt taccaaagtc aattcttaac aaataattaa
     1201 ctttaatttt tatttttata caaaaattgg tttttctat
//
LOCUS       DAMKNB010000206         1133 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.212, whole genome shotgun sequence.
ACCESSION   DAMKNB010000206 DAMKNB010000000
VERSION     DAMKNB010000206.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1133)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1133)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1133
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.212"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            complement(205..1074)
                     /locus_tag="PC494_003707"
     CDS             complement(205..1074)
                     /locus_tag="PC494_003707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HDF3914122.1"
                     /translation="MVIIKAIELYKKLDLEFNIKNINDDWSFMNFENDFITPEFRKKY
                     IGLVLDNAQNINKVYTTTFPDKEIIKQVIDKDEKDILIFSHHAMGYIASDEGFPFHDI
                     PLSYMEEMKNRRISFYVLHSPLDNYSDYSTSVSFAKALGLEIVKPFCKYDDKIEVGVI
                     CKTSLKSIEEIKELIKKSVGHDVKLYDYGDSVLKDGLVAIAAGGGSYPFVAREVAELG
                     INLYITGFTKPLKHFEPVLEFHQIAKDNLINVIGATHYSTEKFACMGMVDYFKNLGLE
                     SEFLQGKYYLEDL"
BASE COUNT          427 a          175 c          108 g          423 t
ORIGIN      
        1 tacatcaaaa aataaactaa aaaatatcga aaaataattt aaaagacatc aaaactaaat
       61 cttctaatca gcaattaaaa gtctattttc ttagtttaaa aaataaagat agatttttta
      121 aaaacactgg ataaataggt aaaaaaataa acagttagta aaataaattt ttactaactg
      181 tttattttta ttgtttaata tgtcctataa atcctctaag taatactttc cttgcaaaaa
      241 ttctgattct aaacctagat ttttaaaata atcaaccatg cccatacacg caaatttttc
      301 tgtagaataa tgagtagcac ctataacatt aattaaatta tcttttgcta tttgatggaa
      361 ctctaatact ggttcaaaat gttttaaagg cttagtaaac ccagtaatat atagatttat
      421 accaagttca gcaacttctc ttgctacaaa tggataactt cctccccctg ctgcaatagc
      481 aactaaacca tcttttaata cagaatctcc ataatcatac aatttcacat catgaccaac
      541 agatttttta attaattcct taatctcttc tattgatttt agtgatgttt tacatataac
      601 tcctacctca attttatcgt catatttaca aaatggtttg actatttcta aacccagagc
      661 ttttgcaaaa ctaacagaag ttgaatagtc actatagttg tctagtggag aatgtaatac
      721 ataaaaagaa attctacgat ttttcatctc ttccatataa gatagtggta tgtcgtgaaa
      781 tggaaaacct tcatctgatg ctatgtatcc cattgcatga tgtgaaaaaa ttaaaatatc
      841 tttttcatct ttatctataa cttgcttaat tatttcttta tcaggaaaag tagttgtgta
      901 tactttatta atattttgag cattatctaa tactaatcct atgtattttt ttctaaattc
      961 tggagtaata aaatcatttt caaaattcat aaaactccaa tcatcattaa tatttttaat
     1021 attaaattct aaatctaatt ttttataaag ttcaattgcc ttaataataa ccactccttt
     1081 ataataatat tgaattacta catattaata tagaaatttc cgataataaa ctt
//
LOCUS       DAMKNB010000207         1106 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.213, whole genome shotgun sequence.
ACCESSION   DAMKNB010000207 DAMKNB010000000
VERSION     DAMKNB010000207.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1106)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1106)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1106
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.213"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            complement(155..865)
                     /locus_tag="PC494_003708"
     CDS             complement(155..865)
                     /locus_tag="PC494_003708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF3914123.1"
                     /translation="MTSICICDDEKQQRNMLNKIITREMDLWGYPYQIKEYSNGESLV
                     YNLEHENYYIDIIFLDIELGKSNGVDIAKTIRKHSKDTIIIFVTGFSDYVFHGYDVGA
                     LNYILKPYKTEKICKVLKEALKKLEQWKENFITVQIGTNLCKINTKDILYFKSELRKL
                     TVVTFDKTLEYYGKLNDMETVLPSNFIRTHQRYIVNLNHVDSITQTYAKVQNEKIPIS
                     RKKYQEVVGKFTRYMLES"
BASE COUNT          392 a          149 c          117 g          448 t
ORIGIN      
        1 tctaaaaact aagcttcaaa aaattaaatt ttgaaagatt gaaattctag aaattaatct
       61 tcaaaaaatt aaatttgaaa aaacaaaact ctaaaaacta agctttaaaa aattaagttt
      121 caaaaataaa attctagaga ttgaacttca aaaattaaga ttctaacata taccttgtaa
      181 attttcctac aacctcttga tattttttac ggcttatagg aattttttca ttctgaactt
      241 tggcataagt ttgagttata ctatctacat ggtttagatt gacaatatac ctttgatgcg
      301 tacgtataaa attagaggga agaacagttt ccatatcatt taattttccg tagtattcta
      361 atgttttatc aaaggtaact acagttaatt ttcttagctc acttttaaag tagaggatat
      421 cttttgtatt aattttacaa agattagttc caatctgaac tgtaataaag ttttctttcc
      481 attgttctaa tttttttagt gcttctttta atactttaca tattttttca gttttataag
      541 gttttaagat gtagttcaat gctcctacat catatccatg aaatacatag tcagaaaaac
      601 ctgtgacaaa gatgattata gtatcctttg aatgttttcg tatagttttt gctatgtcaa
      661 cgccattact ttttccaagt tcaatatcta aaaaaataat atctatgtaa taattttcgt
      721 gttctagatt gtatactaga ctttctccat ttgaatattc ttttatttgg taggggtagc
      781 cccacaaatc catttctctt gtaatgattt tattcagcat gtttctttgt tgtttttcat
      841 catcacaaat acaaatcgaa gtcaattttt tatctccttt caaattttat atttatatag
      901 ttaagtatat aatatatttt gctacctaga tatataaaat gaaataacaa ttatatccag
      961 atagcaaaat aaaatttttt atattagtat acttacactt aaaactattc tattaaactt
     1021 attctgaagt gctaatgatt ttcttattaa aaaatctaac aatctttctt attataaaat
     1081 acaaatgctt ttattattat aaaaag
//
LOCUS       DAMKNB010000208         1096 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.214, whole genome shotgun sequence.
ACCESSION   DAMKNB010000208 DAMKNB010000000
VERSION     DAMKNB010000208.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1096)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1096)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1096
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.214"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            162..914
                     /gene="cwlD"
                     /locus_tag="PC494_003709"
     CDS             162..914
                     /gene="cwlD"
                     /locus_tag="PC494_003709"
                     /EC_number="3.5.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase CwlD"
                     /protein_id="HDF3914124.1"
                     /translation="MEYYSVFISIHIQGDVVRKYIKHIIFSFAMICLVVVSIFEIKNI
                     SEDVIKYMPVTNKTIILDAGHGGIDPGALNKDKSTSEKDINLAITLKLRELIESSGGL
                     VILTREDDSSLYKEENNKTTRQKYNENLKNRKEIISNSNANMFVSIHLNAFEQSKYYG
                     AQTFYPKDKQDSKELSKCIQEELKRVVDKTNNREVKPRDDIYLLKENNIPSVLIECGF
                     LSNEKECKLLTDETYQEKIAWAIYIGIQKYLS"
BASE COUNT          487 a          111 c          166 g          332 t
ORIGIN      
        1 ataatataaa ctaagtataa tttattgtat agtattgaat gttagataaa catagtgaat
       61 taaatagggg cagaaatata atatcattac ataataatat attaatacca ataaataaag
      121 atatatcaat attaaaaaaa tttaaatgtt tgtactaata tatggaatat tatagtgttt
      181 ttataagtat acatatacag ggtgatgttg tgagaaagta cataaaacat ataattttta
      241 gctttgcaat gatatgtcta gtagtagtat ccatatttga aattaaaaat atttctgaag
      301 atgttatcaa gtatatgcca gtaacaaaca aaactataat tttagatgct ggtcatggag
      361 gcattgatcc aggtgcatta aataaggata agagtacatc tgaaaaggat attaacctag
      421 caataacact taagcttaga gagcttatag aatcaagtgg tggccttgta atattaactc
      481 gagaagatga cagtagcctt tataaagaag aaaataataa aactacaaga caaaaatata
      541 atgagaattt gaaaaataga aaagaaataa tatctaattc taatgccaat atgtttgtct
      601 ctatacatct taatgcattt gaacaatcaa aatactatgg agctcaaact ttttatccta
      661 aagacaaaca agacagtaaa gaattatcga agtgtattca agaagaactt aaaagagtag
      721 tagataagac aaacaacaga gaagtcaaac caagggatga tatatatctt ttgaaagaaa
      781 ataatattcc atcagtactg atagaatgtg gttttttatc aaatgaaaaa gagtgtaaac
      841 tcttaactga tgaaacatat caagaaaaaa tagcatgggc aatctacata ggaatacaaa
      901 aatatttaag ttgaaataac tataaaaata ggtctaaata tgtaaatagc ttgtattaaa
      961 gcagttaaaa tgcattaata taggctattt ttattttgac aaaaaaatat ttaaaataaa
     1021 agttaaaaag ttgttgactt agaataatat agatgatatt atatatgagt gcccaaaagg
     1081 agcaccaaaa taagac
//
LOCUS       DAMKNB010000209         1045 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.215, whole genome shotgun sequence.
ACCESSION   DAMKNB010000209 DAMKNB010000000
VERSION     DAMKNB010000209.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1045)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1045)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1045
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.215"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            complement(577..1017)
                     /locus_tag="PC494_003710"
     CDS             complement(577..1017)
                     /locus_tag="PC494_003710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SufBD protein"
                     /protein_id="HDF3914125.1"
                     /translation="MKNLNLLINKLYSKNHNEAYKTFLFLENESLKSNITYCFFDSFL
                     EMIDNENSYIRTRGLLLISANAQWDIDNKIEINIDSILSHIVDKKPSVSRMFIKSIPN
                     ITKYKENLINRIKMELSNADISIYNNNMKPLVEKDINDTLSNIS"
BASE COUNT          374 a          132 c           76 g          463 t
ORIGIN      
        1 tattattttc attaattata tacctcaata aatttctata aaaatagtat cattttagta
       61 tcatcattta tttaatacat tatgtattcc gtttagattt agttatccga aaacttagat
      121 aactagcttg aaatttctac agattattac atactttatt gtaattatat cataatgtta
      181 taattacata ttatcaaatt acacactatc ttttattcat atagatatta tcatccttgt
      241 gtatatattg tcaaagaaaa catttaattt acaacatatt ttatatcata tcatctaaac
      301 tattatatac accttatcta attcacacat taacactatt gtactttttc taaaaatttt
      361 taaataaaaa tgacagcttt aatttattat tttaaaactg ccattaaact gtaaatattc
      421 ccttttagta tacaaaattt tacctttatg ttaatatatt ttacttatat aaatttttca
      481 taattaattt atacatataa attagcacca ttgttgtttt attatcttag ttataaataa
      541 ttgtaactag ataatattca atttctatat taatatttaa ctaatattag ataatgtatc
      601 gtttatatcc ttttctacta atggtttcat attattatta taaatactta tatctgcatt
      661 acttaattcc atttttatgc gattaataag attttcttta tactttgtaa tattaggtat
      721 ggatttaata aacattcttg atacagaagg ttttttatct acgatatgac ttagtatact
      781 atctatattt atttcaattt tattatcaat atcccactga gcatttgcag agattaataa
      841 caatcccctt gttcgaatat atgagttttc gttatcaatc atttctagga atgagtcaaa
      901 aaaacaatat gtaatatttg attttaaact ttcattttct aagaataaaa aagttttata
      961 tgcttcatta tgattttttg aatataattt attaataagt aaattgagat tcttcaatct
     1021 tctcatctcc ctcattacaa atatt
//
LOCUS       DAMKNB010000210         1024 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.216, whole genome shotgun sequence.
ACCESSION   DAMKNB010000210 DAMKNB010000000
VERSION     DAMKNB010000210.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1024)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1024)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1024
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.216"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            complement(158..841)
                     /locus_tag="PC494_003711"
     CDS             complement(158..841)
                     /locus_tag="PC494_003711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1275 domain-containing protein"
                     /protein_id="HDF3914126.1"
                     /translation="MTSKSQMSESFFLCSLLAITGGFLDIYTYVVRGKVFANAQTGNI
                     VLFGLNIAEGNVKESFYYLIPILAFMLGVFIAEKIRKYFTNNKTKIHWRQVIIIIEMI
                     TILIVSFIPRGRFNMFVNVAISFICSMQVESFRKVNGNSFATTMCTGNLRSATETLFH
                     YIHTKNIFMIKKSLQYYAIIIFFISGAILGTFFTKIFVEKSILICFFILAVVFGIMFI
                     NKDDSFNEN"
BASE COUNT          399 a          158 c           78 g          389 t
ORIGIN      
        1 tttaattaat ttatacactg cttactatac ttaaaatact tctattaact tatacattgc
       61 ttactatatt ttaaattctt taattaatct atacaatatt tgctatatat aaagtatatc
      121 aaataacagc ttcatttttt tgtaaattta cagaaagtta attttcatta aatgaatcat
      181 ctttattgat aaacataatt ccaaagacca ctgccaaaat aaaaaaacat attagtattg
      241 atttttccac gaaaattttt gtaaaaaaag ttcctaaaat agctccagat ataaagaata
      301 taataatagc ataatactgt aaactctttt ttatcataaa aatattctta gtatgtatat
      361 aatgaaataa agtttctgta gcacttctta aatttccagt acacattgtc gttgcaaaac
      421 tattcccatt tacttttcta aaactctcta cttgcattga acaaataaaa gaaatagcaa
      481 catttacaaa catattaaat cttcctctag gaataaatga aacaataagt attgtaatca
      541 tttcaattat aatgataacc tgacgccaat gaatctttgt cttattattt gtaaaatact
      601 ttcttatctt ctcggctata aatacaccta acataaatgc caaaatagga atcaaataat
      661 aaaatgattc ctttacatta ccttctgcta tattaagccc aaacaaaact atatttccag
      721 tttgtgcatt agcaaagact ttacctctta ccacataagt ataaatatcc aaaaatcctc
      781 ctgttattgc caacaaagaa cataaaaaga atgattcaga catctgactc ttgcttgtca
      841 tatataaacc tctcgctttc taatgataga tacaaaatca aaatcatttt agattctatt
      901 tttcattgat ataaaaaaat tatttatatt taaatattgt ctatatttat acatcattta
      961 tatttataca ttatttgtat ttatatagca ttcatattta tttatattta aacattatct
     1021 atat
//
LOCUS       DAMKNB010000211         1018 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.217, whole genome shotgun sequence.
ACCESSION   DAMKNB010000211 DAMKNB010000000
VERSION     DAMKNB010000211.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1018)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1018)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1018
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.217"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            193..699
                     /locus_tag="PC494_003712"
     CDS             193..699
                     /locus_tag="PC494_003712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase"
                     /protein_id="HDF3914127.1"
                     /translation="MGFREVKIEELQFNPFTKIGKEWLLITAGDSEKFNTMTASWGGV
                     GVYWGKNVVTTYIRPQRYTKEFVDSNDTFTIAFFDETYREALNICGTISGRDINKIEK
                     AGLTPYFVDDTVAFEEANMIIVCKKLYHGNMPPENFDAKENDKKWYPEKDYHTMYISE
                     IIKVLVKE"
BASE COUNT          408 a           95 c          153 g          362 t
ORIGIN      
        1 aatcaatata ttttatctat attttacact tataaaatat gaaaactact tattgcgaaa
       61 gtaattgatt tgttgtatta taatttacat gaattatgta ggacaatcaa aagtcagtat
      121 tataagagta catatattca aatttttaac aattaattta tataattaaa aaatgaaggg
      181 taggatgaag tcatgggttt tagagaagta aaaattgagg aattacagtt taatccattt
      241 actaagattg gcaaagaatg gttacttata acagctggtg attcagaaaa gtttaacaca
      301 atgactgcta gctggggtgg tgttggagtc tattggggta aaaatgttgt tacaacttac
      361 ataagaccac agagatatac aaaagaattt gtagatagta atgatacatt tacaattgcc
      421 ttctttgatg aaacgtatag agaagcttta aatatttgtg gcactatttc tggtagagat
      481 ataaataaaa tagaaaaagc aggacttaca ccatattttg tggatgatac ggtagctttt
      541 gaagaagcta atatgattat agtatgtaaa aagctatatc atggtaatat gccaccagaa
      601 aactttgatg ctaaagaaaa tgataaaaaa tggtatccag agaaagacta tcatactatg
      661 tacatttcag aaattataaa agttcttgta aaagaataat tataataaaa aatatatgaa
      721 aagaacttat tataagtaaa tgactgtgct ttcttatctg atatctaagt agatgctact
      781 aactaaataa atattaattt taaataaata ctattataaa aaagatgaac tatatttact
      841 atagttcatc tttttattta tataagcact tatataagta gagatttatt tgaataaaag
      901 tatttatttg aaatatttga gtatacttta taagtatttt tatgctaact agaaacactt
      961 aatttatggc atttgtactt gatttatttt aatgtaaata atttcaaagt taatttta
//
LOCUS       DAMKNB010000212          954 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.218, whole genome shotgun sequence.
ACCESSION   DAMKNB010000212 DAMKNB010000000
VERSION     DAMKNB010000212.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 954)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 954)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..954
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.218"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            272..739
                     /locus_tag="PC494_003713"
     CDS             272..739
                     /locus_tag="PC494_003713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HDF3914128.1"
                     /translation="MKFLNVLVVVEDIEKSKKFYYDVLGLKVICDFGENVVLEGNISL
                     QEKKLWLEFINKSDSEVKFNGNDAELYFEEDNFDTFVERLSTMKDIDYVHLAIEHRWG
                     QRAIRFYDLDGHIIEVGETMSSVCRRFLDSGLSIDEVAKRMDVTVEYIESVLE"
BASE COUNT          367 a           63 c          159 g          365 t
ORIGIN      
        1 attaaaaaaa catagatatt tcagtaatct aaaatagtct acaaaaataa cagttttagc
       61 aaaattaata agaatacata tagatttaaa cctaaaagta tgaacatgtc tgttttttac
      121 aagattaaaa tttatattat atgataaaat taacttaact atttcaataa gacttataat
      181 ttttttcttt atactagacc ttattgaaac ctttatagtt taattctaat tatatattat
      241 aaataaagta tgtgtatatt aaggaggtaa tatgaagttt ttaaatgttt tagtagtagt
      301 tgaagatatt gagaaatcaa aaaagtttta ttatgatgtt ttggggttaa aggtaatctg
      361 tgattttgga gaaaatgttg tattagaagg taatatatca ttacaagaaa aaaagctttg
      421 gttagaattt attaataaga gtgacagtga agttaagttc aatggaaatg atgctgagtt
      481 atattttgag gaagataatt ttgatacttt tgttgaaaga ttgagtacaa tgaaagatat
      541 agattatgtt catctagcta tagagcatag gtggggtcaa agagcaatta gattttatga
      601 tttagatggg catattattg aggttggaga aactatgtca tctgtgtgta gacgtttttt
      661 agatagtggt ctttcaatag atgaggtagc taaaagaatg gatgtaactg tcgaatatat
      721 tgaatcagtt ttagaataga tggattatat taaagtaaaa ttgaggtgaa ggctgtaagt
      781 aaacttgtgt gaaaacaaat ttgcttacag tttttatttt tctaaaataa agaatataat
      841 acttgtttag ctttatttga gtttttaaaa atattatgat atttcttata tatttatact
      901 aaagtttaaa tttagaaaaa atatataaaa gatagttata tttactatta tctt
//
LOCUS       DAMKNB010000213          924 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.219, whole genome shotgun sequence.
ACCESSION   DAMKNB010000213 DAMKNB010000000
VERSION     DAMKNB010000213.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 924)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 924)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..924
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.219"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            14..391
                     /gene="tnpA"
                     /locus_tag="PC494_003714"
     CDS             14..391
                     /gene="tnpA"
                     /locus_tag="PC494_003714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
                     /protein_id="HDF3914129.1"
                     /translation="MVYDCKYHIVFCPKYRKPVLVGEVEKMLKEILPYKADELGAEII
                     EMETDKEHVHLLISCDPQYGIHKVVKGLKGFSSRVLRENFPHLKSSMPSMWTNSYFVG
                     TVGSVSLEVVKQYIENQQVRTKK"
     gene            388..>924
                     /locus_tag="PC494_003715"
     CDS             388..>924
                     /locus_tag="PC494_003715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDF3914130.1"
                     /translation="MIKTHRVKLNLTRTQFELVREKQMESANCWNYIVNLSKEYYFEH
                     KQWIKKNDIQKLIKGKYNLHSQTIQAISDKFDANRKTISELRKKGNTKAKYPYKTKKF
                     YIIPFKASAINRNAKGNLKLSMSKGRYLELDFNVENIKTAEIVWRNGYYLYYTFDNEL
                     NGVVAKGTNTVGVDLGEIH"
BASE COUNT          390 a          106 c          158 g          270 t
ORIGIN      
        1 atctaacaaa aatatagttt atgattgcaa atatcatatt gtattttgcc ctaagtatcg
       61 taaacctgtt ttagttggcg aagttgaaaa gatgttaaaa gaaatactac catataaagc
      121 agatgaactt ggagcagaaa taatagaaat ggaaactgat aaagaacatg tgcacttatt
      181 aatatcttgt gaccctcaat atggaattca taaagtagta aaaggtttaa aaggctttag
      241 ttcgagagta ttaagagaga actttccaca tttaaagtct agtatgccta gcatgtggac
      301 taatagctat tttgtaggta ctgttggttc tgtgagttta gaagtagtta aacaatatat
      361 agaaaatcaa caagttagga caaagaaatg ataaaaactc atagagtaaa attaaaccta
      421 actagaacac aatttgaatt agtaagggaa aagcaaatgg aaagtgctaa ctgttggaac
      481 tacatagtta acttatctaa agaatactat tttgaacata aacaatggat taaaaagaat
      541 gatatacaaa agttaatcaa aggtaagtac aatcttcata gtcaaactat tcaagctata
      601 tcagataaat ttgatgcaaa tagaaagact atatcagaat taagaaaaaa aggtaatact
      661 aaagcaaaat atccatacaa gactaagaaa ttttatataa taccttttaa agctagtgct
      721 attaatagaa atgctaaagg caacttaaaa ttatcaatgt caaaaggcag gtatttagaa
      781 ttagatttta atgttgagaa tataaaaact gctgaaatag tatggcgaaa tggatattat
      841 ttatactaca cttttgacaa tgaattaaat ggagttgtag ccaaaggcac taataccgta
      901 ggtgtagact taggggaaat acat
//
LOCUS       DAMKNB010000214          917 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.220, whole genome shotgun sequence.
ACCESSION   DAMKNB010000214 DAMKNB010000000
VERSION     DAMKNB010000214.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 917)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 917)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..917
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.220"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            389..859
                     /locus_tag="PC494_003716"
     CDS             389..859
                     /locus_tag="PC494_003716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase/bleomycin resistance/dioxygenase
                     family protein"
                     /protein_id="HDF3914131.1"
                     /translation="MKYQVSLLAVKDIEVSKKFYKELFEQEIELDLGKNVTFKGGFAI
                     QEDFAWLTGINPDTIIQKSNNMELYFEVDDFDEFIEKLNYYKDVEFVHKPLKHEWQQR
                     VVRIYDPDKHIIEIGESMEVIARRYLSEGYSVEETSKIIQHPIKFVKQCENSKE"
BASE COUNT          417 a           62 c          163 g          275 t
ORIGIN      
        1 tttttaaata gaggtagtgt aattaaagag aatttttaaa tataaattgt gaagctttaa
       61 tatagatgat aatatatatt ttgcaaatat gacacagtgt tttcgtattt aagatgataa
      121 aataaatagg aattaatgat gatattgaaa aaataaaaat aaaggattaa tataagatat
      181 taaagagata gagataaaag tgttaacaga agatattgaa aaaataaaag attgatataa
      241 gatactgaag aggtagaaac aaaagtgtta atagaagata ctaaaaaagt aaaaataaag
      301 gattaataaa aggtactgaa gagatagaga aaaaaatgtt aatagaagat actgaaaaaa
      361 tagaaataaa aaattaggag gaaaatttat gaaatatcag gtttcattat tagcagtgaa
      421 ggatattgaa gtatcaaaaa aattttacaa agaattattt gagcaagaaa ttgaattgga
      481 cttaggtaaa aatgtaacat ttaaaggagg atttgctata caagaagact tcgcatggct
      541 tacagggatt aatccagata caattataca aaaatcaaat aatatggaac tttattttga
      601 ggttgatgat tttgacgaat ttattgaaaa actcaattat tataaagatg tagagtttgt
      661 ccataagcca ctaaaacatg aatggcaaca aagagtagtg cgtatttatg acccggataa
      721 gcatattatt gagataggag agtctatgga agttatagct agaagatatt tatctgaggg
      781 atactctgta gaagaaactt ctaaaataat tcaacatcca attaaatttg taaagcagtg
      841 tgaaaatagt aaggaatgat tgtttaaatt ataattattt agtagaaatt aattgtaata
      901 gaactaattc aagataa
//
LOCUS       DAMKNB010000215          896 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.221, whole genome shotgun sequence.
ACCESSION   DAMKNB010000215 DAMKNB010000000
VERSION     DAMKNB010000215.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 896)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 896)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..896
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.221"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     regulatory      6..99
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            182..667
                     /locus_tag="PC494_003717"
     CDS             182..667
                     /locus_tag="PC494_003717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SH3 domain-containing protein"
                     /protein_id="HDF3914132.1"
                     /translation="MISELMLKNFRKSSINFKTKIKLNLREKPDINSLKLKSIPEGKI
                     VKLKCVDGIWAEVESNYDKGWLLYKYLERLSNAKNNSNDTIKNRKKNYIGNIRTNGLS
                     LELRNDRTLESKVITTIPDGFKVEVCYSVGKWARVNINKNEKRYSGYVYNQYIEEHLS
                     L"
BASE COUNT          398 a           76 c          134 g          288 t
ORIGIN      
        1 tattattcag atataggcaa tattagataa atctaatgac gcaaaactat agggactaaa
       61 atctttatgt aataaaggtc atgtcagcca gttgccaaaa agataataat tctttttgtt
      121 aaaagtattt ttagagttat atattttaat aacttaatat ttggcaagag gagggcttaa
      181 gatgatatct gaattaatgt taaaaaattt tcgtaaatct agcatcaatt ttaagactaa
      241 aattaaattg aatttaagag aaaaaccaga cataaatagt ttgaaattaa aaagtatacc
      301 agaaggtaaa attgttaagt taaagtgtgt agatggaata tgggcagaag ttgagagtaa
      361 ttatgacaaa ggttggttac tttataaata tttagaaaga ttaagtaatg ctaaaaacaa
      421 tagtaatgat acaataaaaa atagaaaaaa gaattacata ggaaatataa gaacaaatgg
      481 attaagttta gaacttagaa atgatagaac attagaatct aaagttataa ctacaatccc
      541 tgatggtttt aaagttgaag tatgttatag cgttggaaaa tgggcaagag ttaatatcaa
      601 taaaaatgaa aaacgatatt ctggatatgt atataatcaa tacatagaag agcatttaag
      661 tttataatac gatactagca agctttaaat atattaataa atcgcaaaaa agaatcccat
      721 taatgggatt cttttttgta gaaacattat aacagaacta aagagaataa attaactaat
      781 ttatttttat tataaagtaa ttataaatgg taaatttaat tgaaagtaga tttaacttat
      841 actttataca ccaagtatca taaattaata ctactttgaa aaatcttaaa aaaagt
//
LOCUS       DAMKNB010000216          885 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.222, whole genome shotgun sequence.
ACCESSION   DAMKNB010000216 DAMKNB010000000
VERSION     DAMKNB010000216.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 885)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 885)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..885
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.222"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            82..780
                     /locus_tag="PC494_003718"
     CDS             82..780
                     /locus_tag="PC494_003718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDF3914133.1"
                     /translation="MEKKYFEIHGVPSILWGNPSSKLYIYIHGQCGNKEEAEAFANIA
                     VPHECQVLSVDLPEHGERKREKNSFNPWHVVPELVSIMEYAKCHWNQISLYANSIGAW
                     FSMLSFEKENLRECIFVSPILDMQQLISNMMLWANVSEEQLKHELIIPTSFGHTLSWE
                     YLQYVKQHPITQWNVPTKILYGKHDELTEIGVVEKFVEKFNCNLTIIENGKHWFNTPQ
                     ELNSLYEWLNTLVK"
BASE COUNT          341 a          110 c          132 g          302 t
ORIGIN      
        1 attaaattct atattacaac attattttat agtttgatta atttaacaat cactaatata
       61 tcaaactgaa aggagatttt tatggaaaaa aaatatttcg aaattcatgg agttccttca
      121 atcctttggg gaaatccttc aagtaaatta tatatttaca tacatggaca atgtggcaat
      181 aaagaggagg ctgaagcttt tgctaatatt gcagttccac atgagtgtca agttttaagt
      241 gttgatttgc ctgaacatgg agaacgtaaa agagaaaaaa attcatttaa cccatggcat
      301 gttgttccag aattagtatc tattatggaa tatgcaaagt gccactggaa tcaaatttcg
      361 ttatatgcaa atagcattgg agcatggttt agtatgttaa gctttgaaaa agagaactta
      421 agagagtgta tttttgtatc tccaattcta gatatgcaac agctcatttc aaatatgatg
      481 ctttgggcaa atgtatcaga agaacagctt aaacatgaac taattatccc aacttcattt
      541 gggcatactc tttcatggga atatctacaa tatgtaaaac aacatcctat cactcaatgg
      601 aatgtaccaa caaaaatatt atatggtaaa catgatgaac ttactgaaat cggtgttgta
      661 gagaaatttg tagaaaagtt taattgcaac cttactatta tagaaaatgg caaacattgg
      721 tttaacacac cacaagaatt aaattcatta tatgaatggt taaatacttt agttaaataa
      781 aaaataatta tattattaat atgattaaat tatttataaa tgttatttaa ttaattttat
      841 tttagcatta ttaaaataac tacataaaga ataaattagt tatta
//
LOCUS       DAMKNB010000217          753 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.223, whole genome shotgun sequence.
ACCESSION   DAMKNB010000217 DAMKNB010000000
VERSION     DAMKNB010000217.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 753)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 753)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..753
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.223"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            <1..>753
                     /locus_tag="PC494_003719"
     rRNA            <1..>753
                     /locus_tag="PC494_003719"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          207 a          156 c          227 g          163 t
ORIGIN      
        1 tttaactgag cgttcagtta cttgacgtag acccgaaacc gggcgaccta cccatgagca
       61 ggatgaagcg aaagtaaaat ttcgtggagg tccgaaccca cgagcgttga aaagctcggg
      121 gatgacttgt gggtagcggt gaaattccaa tcgagcccgg agatagctgg ttctccccga
      181 aatagcttta gggctagcct caaggtgaga gatacggagg tagagcactg aatgtcctag
      241 ggggtattgc acctaccgaa gactatcaaa ctccgaatgc cgtcatctta tacttgggag
      301 tcagactgtg ggtgataaga ttcatagtcg aaagggcaac agcccagatc gtcagctaag
      361 gtccctaaat gtaagttaag tggtaaagga tgtgggattg cacagacaac caggatgttg
      421 gcttagaagc agccactcat tcaaagagtg cgtaatagct cactggtcga gtgatcctgc
      481 gccgaagatt tccggggcta aaacttacta ccgaagctac ggcatcagta atgatgggta
      541 ggggagcttc ccatacgggt tgaagcatga ccgtaaggac atgtggacag tatgggagtg
      601 agaatgttgg catgagtagc gagatgtggg tgagaatccc acaggccgta aacccaaggt
      661 ttccagggga aggttcgtcc gccctgggtt agtcgggacc taagctgagg ccgaaaggcg
      721 taggtgatgg acaacaggtt gatattcctg tac
//
LOCUS       DAMKNB010000218          716 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.224, whole genome shotgun sequence.
ACCESSION   DAMKNB010000218 DAMKNB010000000
VERSION     DAMKNB010000218.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 716)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 716)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..716
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.224"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            complement(<1..634)
                     /locus_tag="PC494_003720"
     rRNA            complement(<1..634)
                     /locus_tag="PC494_003720"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          173 a          182 c          127 g          234 t
ORIGIN      
        1 ctacttaacg taactcgttg gcccgttcta caaaaagtac gcggtcacac aagaaatgtg
       61 cttccacagc ttgtaagtgc agggtttcag gttctatttc actcccctcc cggggttctt
      121 ttcacctttc cctcacggta ctatacgcta tcggtcacta ggtagtattt agccttggag
      181 ggtggtccct cctgcttccc acagggtttc acgtgtcccg tggtactctg gatcatatct
      241 aaagtcttct cgtttaacat acaggactat taccttctgt ggtgggtctt tccaaacctc
      301 ttcaattacg atacctcttc gttatgatat gtccgcaacc ccaataaaga aaactttatt
      361 ggtttgggct aatccgcgtt cgctcgccgc tacttacgga atcgaatttc tttctcttcc
      421 ttcaggtact tagatgtttc agttccctga gttcccctca ttaagctatg tattcactta
      481 atgatactta gacattactc taagtgagtt tcctcattcg gaaatcttcg gatcaaagtt
      541 tacgtgcaac tccccgaagc ttatcgcagc ttatcacgtc cttcatcggc tcctagtgcc
      601 aaggcatccg ccctgcaccc ttaataactt gaccagttaa aaaggtttga tagattagaa
      661 gctatcaact tcgataattt taaaaagtta tcagctttat atattacaaa ttagat
//
LOCUS       DAMKNB010000219          701 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.225, whole genome shotgun sequence.
ACCESSION   DAMKNB010000219 DAMKNB010000000
VERSION     DAMKNB010000219.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 701)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 701)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..701
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.225"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            92..>701
                     /locus_tag="PC494_003721"
     CDS             92..>701
                     /locus_tag="PC494_003721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HDF3914134.1"
                     /translation="MLDAFITIVSSIIEIWSCKKVFDYTSQSKTDLKKLNMYFLFSVF
                     LIISSLYINIGANSRILICIFVMFVFYKSNYKVNIYKCLVISFFYWLILIGINGLSML
                     LVATVSNLDNMNVLLSGSLYRYEAIFLGKIMLGILLYVYKASFKNFKISKKEIYICIP
                     MIANLLSFFVLYDYIINLVKISPERRTAFLVIVLLLILSNISI"
BASE COUNT          242 a           58 c           91 g          310 t
ORIGIN      
        1 tttaagtgtg ttttttatgc tataattagt atgtattttt tatgatatat tttataaaaa
       61 atataattta atcatttttg aggatattat tatgttagat gcatttataa caattgtttc
      121 ttctattata gaaatatggt catgtaaaaa agtttttgat tatactagtc agtcaaagac
      181 cgacttaaaa aaactaaata tgtattttct cttttctgtt tttctcatta tttcttcttt
      241 atatataaat ataggagcta atagtagaat cttgatatgt atatttgtaa tgttcgtttt
      301 ctataagtct aactataagg ttaatatata taaatgtctg gtaatctcat ttttttattg
      361 gttaatatta ataggtataa atggattaag tatgttatta gtagcaacag taagcaattt
      421 ggataatatg aatgttttac ttagtggcag tttatataga tatgaagcaa tattcttggg
      481 aaagataatg ttaggtatat tactttatgt ttataaggct tcttttaaaa attttaaaat
      541 aagtaaaaaa gagatataca tatgtattcc tatgatagca aatttattgt cattttttgt
      601 actttatgat tatattatta atcttgtaaa aatctctcct gaaagaagaa ctgctttttt
      661 agtaatagtt ttactattaa tattatctaa catttcaatc t
//
LOCUS       DAMKNB010000220          677 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.226, whole genome shotgun sequence.
ACCESSION   DAMKNB010000220 DAMKNB010000000
VERSION     DAMKNB010000220.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 677)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 677)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..677
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.226"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            153..293
                     /locus_tag="PC494_003722"
     CDS             153..293
                     /locus_tag="PC494_003722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3914135.1"
                     /translation="MENLMMSIITGVIASYIYDKLKSHSERPTKSGWELNIKFQKSKS
                     SK"
BASE COUNT          290 a           66 c           92 g          229 t
ORIGIN      
        1 taaaaaataa taataaagac gataagtatt aaaattttat gtttccaata tttatgatat
       61 aattaatatg gcaaggaata aatatttgaa aaagctatga gtggtgtttc catggaagtt
      121 tcttcacttt cttatgagag gaggtgaaaa ctatggaaaa tctaatgatg agtattataa
      181 ctggtgttat agccagttac atttacgata aattaaagag ccactctgag cgaccaacta
      241 agagtggctg ggaacttaat ataaagttcc agaaaagtaa atcttcaaaa taatttgttg
      301 aaggaaacat cactcaaagt taagtaaaat atgtttcctt gcttttatta tatcacaaat
      361 taaaaatatt aacacaaaat tttgtgaata tatacttatt attgttctaa aaaaatatgt
      421 aaataattga tttgattgca tggaattatt gatgtaatat ttaagttaaa tatacacaat
      481 ctcaattaaa gaagataagt actataaatt catatcaaaa aaatacataa acttttaagt
      541 tataatttta taaaaagtct tttagtatca ttatttcaag aggaattatc atatgaaaaa
      601 ataacttcat tagaaaagtg gataaaaaac tggtaagaag atgactaaag attacatata
      661 ctattactta aattaaa
//
LOCUS       DAMKNB010000221          664 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.227, whole genome shotgun sequence.
ACCESSION   DAMKNB010000221 DAMKNB010000000
VERSION     DAMKNB010000221.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 664)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 664)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..664
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.227"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            complement(<1..>664)
                     /locus_tag="PC494_003723"
     rRNA            complement(<1..>664)
                     /locus_tag="PC494_003723"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT          152 a          191 c          151 g          170 t
ORIGIN      
        1 gatccagccg caccttccga tacggctacc ttgttacgac ttcaccccag ttattgattc
       61 caccttcgac gacttcttcc aaaaggttag ataatcggct tcgggcgtct ccaactcccg
      121 tggtgtgacg ggcggtgtgt acaagacccg ggaacgcatt caccgcagca ttctgatctg
      181 cgattactag taactccagc ttcatgtagg cgagtttcag cctacaatcc gaactgagag
      241 tagctttaag ggattagctc caccttacgg cttggcaacc ctctgtacta cccattgtag
      301 cacgtgtgta gccctaagca taaggggcat gatgatttga cgtcatcccc accttcctcc
      361 aggttatccc tggcagtctc tctagagtgc ccaacttaat gatggcaact aaagacaagg
      421 gttgcgctcg ttgcgggact taacccaaca tctcacgaca cgagctgacg acaaccatgc
      481 accacctgtc accaatgtcc ccgaagggaa ctctccgatt aaggagatgt cattgggatg
      541 tcaagcttag gtaaggttct tcgcgttgct tcgaattaaa ccacatgctc cgctacttgt
      601 gcgggtcccc gtcaattcct ttgagtttca ctcttgcgag cgtacttccc aggcggagta
      661 ctta
//
LOCUS       DAMKNB010000222          620 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.228, whole genome shotgun sequence.
ACCESSION   DAMKNB010000222 DAMKNB010000000
VERSION     DAMKNB010000222.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 620)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 620)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..620
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.228"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            360..524
                     /locus_tag="PC494_003724"
     CDS             360..524
                     /locus_tag="PC494_003724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3914136.1"
                     /translation="MFGKPKESVRFLDFNDVAEKFGEKKAVAIFDAIAGKKSKEHIIK
                     DIEKLVKNEV"
BASE COUNT          240 a           43 c           89 g          248 t
ORIGIN      
        1 tgtcattatt aaatctttta tacatttttt attttaaata aattgaatat taaggtgatt
       61 atatttacat atttgtattt ttatgaacta gaatattctt tataaattca tagcagtttt
      121 aatagataac tttttcagat agattaaaca aagttttatt tactgtattc tattatcagt
      181 ttcctacaaa ttaaattgtc tatttttatt tatagagtag aataaactgt ttttgttaag
      241 aattttgaag gtaaaactag tttaaaaaaa taaagggact aatttgtcta acgtttattg
      301 gtgaaaaata agtctataga agttataata aatatataaa aatgtatgag aggtgttata
      361 tgtttggtaa accaaaagaa agtgttagat ttttagactt taatgatgta gcagaaaagt
      421 ttggagagaa aaaggctgtt gcaatttttg atgccatagc tggaaaaaaa tctaaagaac
      481 atattatcaa agatatagaa aaattagtaa aaaatgaagt ttagatattt ataaggtata
      541 ttgagcttga gggtagctct ttataccttc ttttttatga tttttagata atattttaaa
      601 atttaaataa gaaacttatt
//
LOCUS       DAMKNB010000223          588 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.229, whole genome shotgun sequence.
ACCESSION   DAMKNB010000223 DAMKNB010000000
VERSION     DAMKNB010000223.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 588)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 588)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..588
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.229"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            complement(81..560)
                     /locus_tag="PC494_003725"
     CDS             complement(81..560)
                     /locus_tag="PC494_003725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2975 domain-containing protein"
                     /protein_id="HDF3914137.1"
                     /translation="MSNKLIKNLLSGILQILFFLLGLVIVVGGFKSFMYLCFSGEATL
                     QGTIYGILMFILGVSYFIIIKSLIEVLGSSEYSLFVKENVKRFRIIGYLLLLNSLIEF
                     ISTFGTTGKGMRFLDLGFGFYFTVPVFVYFITSLMSFVIADGFVKAIKIKEDNDLTI"
BASE COUNT          234 a          102 c           46 g          206 t
ORIGIN      
        1 accctaatat attttatttt aaattactag ttagtcactc ttttcgggtt atttatctcc
       61 tatatattaa agtgtcacac ctaaatagtt aaatcattat cctcttttat ctttattgcc
      121 tttacaaatc catctgcaat tacaaaactc atcagagaag ttataaaata tacaaatact
      181 ggaacagtaa aataaaatcc aaatcctaaa tctagaaatc tcattccttt tccagtagta
      241 ccaaaagttg aaataaactc aattagagag tttaaaagca aaagatatcc aataatccta
      301 aatcttttta cattctcttt tacaaatagg ctatattcag aactacctaa tacttctatc
      361 aatgatttta taatgataaa atatgataca cctaaaataa acattaatat tccataaata
      421 gtaccttgta gagttgcttc tccactaaaa cagaggtaca taaaactttt aaatcctcct
      481 acaacaatta ctaatcctaa aagaaaaaat aaaatttgta atataccact tagtaaattt
      541 tttataagtt tattagacat catgccaact cctttaaaat attttata
//
LOCUS       DAMKNB010000224          587 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.230, whole genome shotgun sequence.
ACCESSION   DAMKNB010000224 DAMKNB010000000
VERSION     DAMKNB010000224.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 587)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 587)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..587
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.230"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            <1..584
                     /locus_tag="PC494_003726"
     CDS             <1..584
                     /locus_tag="PC494_003726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDF3914138.1"
                     /translation="NREGRSIKQFRNKMYAYISKRLSKCKKGSRQSKKLWRLKNKIRS
                     KTDNQLMNLYHQTTRKFIDFCVEQKVCEIVLGDIKGVEKDTKKKKRLNRVNRQKISQM
                     EYGRIKDYIKYKAKEQGIEVKLVKENYTSQTCPKCSKKHKPTGRTYSCTCGYETHRDI
                     VGAWNILNKKHKYGLVDFRINHKQPINLKVSTV"
BASE COUNT          265 a           55 c          107 g          160 t
ORIGIN      
        1 ctaatagaga aggcagaagt attaaacaat ttagaaataa gatgtatgct tatatatcta
       61 aaagattaag taaatgtaaa aaaggtagta gacaatcaaa gaagttatgg agattaaaaa
      121 ataagataag aagtaaaaca gataatcagt taatgaattt atatcatcaa acaactagaa
      181 agtttataga cttttgtgta gagcagaagg tatgtgaaat agttcttggg gatataaaag
      241 gggttgaaaa agatactaag aaaaagaaaa gattaaacag agttaataga cagaaaatat
      301 ctcaaatgga gtatggtcga ataaaggact atataaaata taaagcaaaa gagcaaggta
      361 ttgaagttaa gttagttaaa gaaaactaca cttctcaaac ttgcccaaag tgttctaaaa
      421 aacacaaacc aactggtaga acttatagtt gtacttgtgg ttatgaaact catagagata
      481 tagttggtgc ttggaatatt ttaaataaaa agcataaata tggtttagta gattttagaa
      541 taaatcataa gcaaccaata aatttaaaag tatctaccgt ttgagcc
//
LOCUS       DAMKNB010000225          577 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.231, whole genome shotgun sequence.
ACCESSION   DAMKNB010000225 DAMKNB010000000
VERSION     DAMKNB010000225.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 577)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 577)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..577
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.231"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            <1..>577
                     /locus_tag="PC494_003727"
     rRNA            <1..>577
                     /locus_tag="PC494_003727"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT          154 a          121 c          190 g          112 t
ORIGIN      
        1 caggatggac ccgcgtctga ttagctagtt ggtaaggtaa cggcttacca aggcgacgat
       61 cagtagccga cctgagaggg tgatcggcca cattggaact gagacacggt ccaaactcct
      121 acgggaggca gcagtgggga atattgcaca atgggcgaaa gcctgatgca gcaacgccgc
      181 gtgagtgatg aaggccttcg ggtcgtaaaa ctctgtcctc aaggaagata atgacggtac
      241 ttgaggagga agccccggct aactacgtgc cagcagccgc ggtaatacgt agggggctag
      301 cgttatccgg atttactggg cgtaaagggt gcgtaggcgg tctttcaagt caggagtgaa
      361 aggctacggc tcaaccgtag taagctcttg aaactgggag acttgagtgc aggagaggag
      421 agtggaattc ctagtgtagc ggtgaaatgc gtagatatta ggaggaacac cagttgcgaa
      481 ggcggctctc tggactgtaa ctgacgctga ggcacgaaag cgtggggagc aaacaggatt
      541 agataccctg gtagtccacg ctgtaaacga tgagtac
//
LOCUS       DAMKNB010000226          577 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.232, whole genome shotgun sequence.
ACCESSION   DAMKNB010000226 DAMKNB010000000
VERSION     DAMKNB010000226.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 577)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 577)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..577
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.232"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            complement(<1..>577)
                     /locus_tag="PC494_003728"
     rRNA            complement(<1..>577)
                     /locus_tag="PC494_003728"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          126 a          168 c          133 g          150 t
ORIGIN      
        1 gggggagata agcctgttat ccccagggta gcttttatcc gttgagcgat ggcccttcca
       61 cgcagaacca ccggatcact aagtccgatt ttcatccttg ctcgacctgt atgtcttgca
      121 atcaagctct cttttgcctt tacactctac gtacgatttc cgaccgtact gagagaacct
      181 ttgagcgcct ccgttacctt ttgggaggcg accgccccag tcaaactgcc cacctgacag
      241 tgtcccaaga ccagattcat ggcctatggt tagagtccca gtactacaag ggtggtatcc
      301 caaggatggc tccgccaaaa ctggcgtcct ggtttcaaag cctcccacct atcctgtaca
      361 tgtagtacca agacccaatg tcaagctaca gtaaagctcc atggggtctt tccgtcctgt
      421 cgcaggtatc cggcatcttc accggaatta caatttcacc gagtctgttg ttgagacagt
      481 gcccaaatcg ttacgccttt cgtgcgggtc ggaacttacc cgacaaggaa tttcgctacc
      541 ttaggaccgt tatagttacg gccgccgttt actgggg
//
LOCUS       DAMKNB010000227          573 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.233, whole genome shotgun sequence.
ACCESSION   DAMKNB010000227 DAMKNB010000000
VERSION     DAMKNB010000227.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 573)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 573)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..573
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.233"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            <1..>573
                     /gene="tuf"
                     /locus_tag="PC494_003729"
     CDS             <1..>573
                     /gene="tuf"
                     /locus_tag="PC494_003729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887863.1"
                     /note="EF-Tu; promotes GTP-dependent binding of
                     aminoacyl-tRNA to the A-site of ribosomes during protein
                     biosynthesis; when the tRNA anticodon matches the mRNA
                     codon, GTP hydrolysis results; the inactive EF-Tu-GDP
                     leaves the ribosome and release of GDP is promoted by
                     elongation factor Ts; many prokaryotes have two copies of
                     the gene encoding EF-Tu; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HDF3914139.1"
                     /translation="IPAPERDTDKPFLMPVEDVFSITGRGTVATGRVERGVLKVQDEV
                     ELVGLTEAPRKVVVTGVEMFRKLLDQAQAGDNIGALLRGVQRNEIERGQVLAKTGSVK
                     AHTKFTAEVYVLKKEEGGRHTPFFDGYRPQFYFRTTDVTGACKLPEGIEMVMPGDNVT
                     MEVDLINSIVVEEGLRFSIREGGRTVASGV"
BASE COUNT          242 a           77 c          140 g          114 t
ORIGIN      
        1 atataccagc tccagagaga gatacagata aaccattctt aatgccagta gaggacgtat
       61 tctcaatcac aggaagagga acagttgcaa caggaagagt ggaaagagga gtactaaaag
      121 tacaagacga agtagaatta gtaggattaa cagaagcacc aagaaaagta gtagtaacag
      181 gagtagagat gttcagaaaa ttattagacc aagcacaagc aggtgataat ataggagcat
      241 tattaagagg agtacaaaga aacgagatag aaagaggaca agtactagca aagactggat
      301 cagtaaaggc acacacaaag tttacagcag aagtatatgt acttaaaaaa gaagagggtg
      361 gaagacatac accattcttt gatggatata gaccacaatt ctatttcaga acaacagacg
      421 taacaggagc ttgtaagtta ccagaaggaa tagagatggt aatgcctgga gataacgtaa
      481 caatggaagt agacttaata aactcaatag ttgtagaaga gggattaaga ttctcaataa
      541 gagaaggtgg aagaacagta gcttcaggag ttg
//
LOCUS       DAMKNB010000228          548 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.234, whole genome shotgun sequence.
ACCESSION   DAMKNB010000228 DAMKNB010000000
VERSION     DAMKNB010000228.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 548)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 548)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..548
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.234"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            complement(329..529)
                     /locus_tag="PC494_003730"
     CDS             complement(329..529)
                     /locus_tag="PC494_003730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003723180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HDF3914140.1"
                     /translation="MNNGIVKWFNNEKGFGFISMESGDDVFAHFSAIQTSGFKSLEEG
                     QKVSFDIVKGARGPQAENITIL"
BASE COUNT          196 a           69 c           58 g          225 t
ORIGIN      
        1 atgttttaat tgttttttat taacaaatta ctaaaagtgt tatatcagaa ttgaatacaa
       61 aagaaagagt atgtatttat gagatagttg aaaattttga tgtgccacaa ctaaaattat
      121 tatattacta tatattctaa ttaaaagagt acttgtaggt ttaagtacat actttataaa
      181 tatatttttg tcagatttat tttataaaaa gtatttagac taagtattat ttttaagtat
      241 tttcttgttg aagttatttt ttcctttttt acaaaatgcg taaataaaaa aaagactctt
      301 aaaagagtct ttccgaaaaa tctatatatt ataatatagt tatattttct gcttgaggac
      361 ctctagcgcc tttaactata tcaaagctta ctttttgacc ttcttctaat gatttaaatc
      421 ctgaagtttg tatagctgag aaatgagcaa atacgtcatc tccactttcc attgatataa
      481 atccaaatcc tttttcatta ttaaaccatt ttactattcc attattcatt aaaaatactc
      541 ctattaac
//
LOCUS       DAMKNB010000229          541 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.235, whole genome shotgun sequence.
ACCESSION   DAMKNB010000229 DAMKNB010000000
VERSION     DAMKNB010000229.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 541)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 541)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..541
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.235"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
BASE COUNT          216 a           43 c           65 g          217 t
ORIGIN      
        1 ataaaaaaga atatgagttg taaaatatta aataatattg tactaattgg aataatttta
       61 actttattat agattatttt aataccatta gtactgatgg tgtattttaa aattggtata
      121 agcattacaa atacgaatat gccaactgta atatgtaata taagtagcta tatacatatg
      181 tgctgtccca tatattgtat cattgtttat attaaaaaga ttatgtaaat tggtatcaat
      241 caataaatca ttttcagaag aaatacctaa aaacttaaaa aatacctata tgtgtattta
      301 gttagatttg agatttttac atttaatttt atagtgacaa tattatatta tttttatgat
      361 gtctatttat atgcaattac tataatatca gaacttatag tatcatttgt ttcattatca
      421 ataaggtttt ttactttagt tttgtcaatt ttattaaaaa aagttattga tataaaagat
      481 aagaaggata aaactatatg acggatttca aacataagag tggatattta tataatagat
      541 a
//
LOCUS       DAMKNB010000230          493 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.236, whole genome shotgun sequence.
ACCESSION   DAMKNB010000230 DAMKNB010000000
VERSION     DAMKNB010000230.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 493)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 493)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..493
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.236"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            188..304
                     /gene="rrf"
                     /locus_tag="PC494_003731"
     rRNA            188..304
                     /gene="rrf"
                     /locus_tag="PC494_003731"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
     gene            310..398
                     /locus_tag="PC494_003732"
     tRNA            310..398
                     /locus_tag="PC494_003732"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:344..346,aa:Leu,seq:taa)
     gene            410..486
                     /locus_tag="PC494_003733"
     tRNA            410..486
                     /locus_tag="PC494_003733"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:444..446,aa:Ile,seq:cat)
BASE COUNT          156 a           91 c          109 g          137 t
ORIGIN      
        1 attcattaag atatatgtgc agtttttaga gtgctaactc tatattttta aacttgtcaa
       61 aacttatgaa tttttaatag ttttataagg caaaaaatcg aataaaaaaa gtattgacac
      121 aataagacaa agatgttatt ataatacttg tcttagaaaa aaagttaaat gaaaatttag
      181 acaataatct ggttataata gcagagagga tacacctgtt cccattccga acacagaagt
      241 taagctctct agcgctgatg gtacttggtg ggaaactgcc tgggagagta ggacatagcc
      301 aggtgatgtg ccgaagtggc ggaactggca gacgcacagg acttaaaatc ctgcgggact
      361 tacctctcgt accggttcga ttccggtctt cggcaccaca aattattgtg ggccattagc
      421 tcagttggtt agagcgcccg gctcataacc ggtaggtctg gggttcgagt ccctgatggc
      481 ccaccacaat aat
//
LOCUS       DAMKNB010000231          374 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.237, whole genome shotgun sequence.
ACCESSION   DAMKNB010000231 DAMKNB010000000
VERSION     DAMKNB010000231.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 374)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 374)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..374
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.237"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
BASE COUNT          141 a           22 c           42 g          169 t
ORIGIN      
        1 aaattaattt aggaattatt tgatttattc atttataaaa attaattact gatttgtcga
       61 aaccattgta ataagaaaaa aatgaaaaaa taaagtgtga atatgttgca aatactgtat
      121 tttgataaaa agtagtcatt tcttgtaaaa tggatagttt atatctactt taattttgta
      181 aaattttctg ctactataat tatagaatgt agtatattca ttgtcttaac tattgattta
      241 tatatttcat ataggtataa tagaaaataa attggattat tttggcatat aattatttat
      301 taaaaggtga ttatttttgt ttaaattgtc tgaaaaattt tatttttata ttataatttt
      361 aatattttct tttc
//
LOCUS       DAMKNB010000232          368 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.238, whole genome shotgun sequence.
ACCESSION   DAMKNB010000232 DAMKNB010000000
VERSION     DAMKNB010000232.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 368)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 368)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..368
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.238"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            complement(<1..>368)
                     /locus_tag="PC494_003734"
     rRNA            complement(<1..>368)
                     /locus_tag="PC494_003734"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT           86 a          108 c           79 g           95 t
ORIGIN      
        1 ctattagtat cgataagcta aatacattgc tgcacttaca ccttcgacct atcaaccaga
       61 tagtctttct ggggtcttac ccttgcggtg ggaaatctta tcttgaagtt ggcttcgcgc
      121 ttagatgctt tcagcgctta tccattccgt acatagctac ccagccatgc ccttggcagg
      181 acaactggta caccagaggt acgtccatcc cggtcctctc gtactaagga caggtcttct
      241 caaatttcct acgcctgcga cggataggga ccgaactgtc tcacgacgtt ctgaacccag
      301 ctcgcgtacc actttaatgg gcgaacagcc caacccttgg gacctactac agccccagga
      361 tgtgatga
//
LOCUS       DAMKNB010000233          363 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.239, whole genome shotgun sequence.
ACCESSION   DAMKNB010000233 DAMKNB010000000
VERSION     DAMKNB010000233.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 363)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 363)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..363
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.239"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            167..283
                     /gene="rrf"
                     /locus_tag="PC494_003735"
     rRNA            167..283
                     /gene="rrf"
                     /locus_tag="PC494_003735"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
     gene            290..361
                     /locus_tag="PC494_003736"
     tRNA            290..361
                     /locus_tag="PC494_003736"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:322..324,aa:Asn,seq:gtt)
BASE COUNT          116 a           61 c           78 g          108 t
ORIGIN      
        1 ttcattaaga tatatgtgca gtttttagag tgttaactct atgtaaagta ctaacttcaa
       61 ttgatgaagt atatatcgta aaaacaatta ctatttagta cttcaaaact attgacattt
      121 aaaaataaag atgttaatat aatacttgtc ttataaatag gcaatatgtg gttataatag
      181 caaagaggat acacctgttc ccattccgaa cacagaagtt aagctcttta gcgctgatgg
      241 tacttggtgg gaaactgcct gggagagtag gacgtagcca cgtgaatatt ccaaggtagc
      301 tcaatggtgg agcaaccggc tgttaaccgg taggctgtgg gttcgagccc cacccttgga
      361 gcc
//
LOCUS       DAMKNB010000234          343 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.240, whole genome shotgun sequence.
ACCESSION   DAMKNB010000234 DAMKNB010000000
VERSION     DAMKNB010000234.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 343)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 343)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..343
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.240"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
BASE COUNT          151 a           31 c           36 g          125 t
ORIGIN      
        1 ttgaattgtc attaaatatg ccaatagttt tatatattat tgattttatt aaaaaaagag
       61 atatacaaac taataagttg taatctctca aatataaaaa aacaataaat tagctcattg
      121 gattttttag tccataatat aattatagat tattcaccaa acaatctata gaaattgtgg
      181 tattaatgtt taaataacca actttttcta aaataacctt tataggaata tatgagttca
      241 taagtaaaga tagcgaaata agaaaccagt ttggtatgta aaatctagat ttttaattaa
      301 attatcaaga ttatatatta tagtatcaaa aatagaaaat taa
//
LOCUS       DAMKNB010000235          323 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.241, whole genome shotgun sequence.
ACCESSION   DAMKNB010000235 DAMKNB010000000
VERSION     DAMKNB010000235.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 323)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 323)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..323
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.241"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
BASE COUNT          150 a           24 c           34 g          115 t
ORIGIN      
        1 atgaaaatag tgggttttat aaaaaaacat atttagattt taacatctca aaggagtttt
       61 caaagctaat atttcatttt taaataaaaa aataaaatat tagttttgat ttctggttta
      121 aattgggtta taataaattg tcaaattatt tattaatata aaatagacta taaaacaagc
      181 aaaaatcata ctattatata aaagacctta aagatagaaa actacagaaa gaagccaaaa
      241 tgtttttgaa aaaaatgaaa ttttattgca aaaaaatcaa aatgaattta acttaatagt
      301 tataatctat ttttagtgtt ata
//
LOCUS       DAMKNB010000236          314 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.242, whole genome shotgun sequence.
ACCESSION   DAMKNB010000236 DAMKNB010000000
VERSION     DAMKNB010000236.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 314)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 314)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..314
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.242"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
BASE COUNT          137 a           24 c           39 g          114 t
ORIGIN      
        1 gtattaataa aaaagatatt acattaatat gaaaatatag gagattagaa gtgtttgata
       61 attacagtac atgttagata tatcattgta aattaacata gctttgaata taataatgtt
      121 caaaaggcaa tatttttgag gtctgaatcc aataataata tagtcttatg attgtagata
      181 tcaaaaaata taagttacta agaatacgtt ttgtagattt atatatgatt aataactaaa
      241 gctataaata aacaaaataa aaagagtatg tttcaaccta tagcttttag atttaaaata
      301 tactctttta ttaa
//
LOCUS       DAMKNB010000237          251 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.243, whole genome shotgun sequence.
ACCESSION   DAMKNB010000237 DAMKNB010000000
VERSION     DAMKNB010000237.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 251)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 251)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..251
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.243"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            <1..>251
                     /locus_tag="PC494_003737"
     rRNA            <1..>251
                     /locus_tag="PC494_003737"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT           75 a           49 c           70 g           57 t
ORIGIN      
        1 ctaagcacac tgttggttat gtgtgcccaa gcattgaggc agtcaaagta ggcaaatccg
       61 ctttgataat gctgggatgt gatggggagc gaaatttagt agcgaagtag ctgatttcac
      121 actgtcaaga aaagtctcta tcgaggttaa aggtacccgt accgcaaacc gacacaggtg
      181 ggtgaggaga gtatcctaag gccagcgaga gaactgttgt taaggaactc ggcaaaatga
      241 ccccgtaact t
//
LOCUS       DAMKNB010000238          232 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.244, whole genome shotgun sequence.
ACCESSION   DAMKNB010000238 DAMKNB010000000
VERSION     DAMKNB010000238.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 232)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 232)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..232
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.244"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            complement(<1..>232)
                     /locus_tag="PC494_003738"
     CDS             complement(<1..>232)
                     /locus_tag="PC494_003738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002590471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="peptidase dimerization domain-containing
                     protein"
                     /protein_id="HDF3914141.1"
                     /translation="NVIQKIQQLVPPTHPVLGDGILVLTDIKSSPYPGASVVPDYCKA
                     TFDRRLLVGETREGVLAPIQALLDEMMKEDPE"
BASE COUNT           66 a           41 c           37 g           88 t
ORIGIN      
        1 aattctgggt cttctttcat catttcatct aataaagctt gtattggagc taatacgcct
       61 tctcttgttt ctccaactaa taatcttcta tcaaaagtag ctttgcaata atctggcact
      121 actgatgctc ctggatatgg agaagatttt atatctgtta aaactaatat tccatcacct
      181 aaaactggat gagttggagg tactaattgt tgtatctttt ggattacatt ag
//
LOCUS       DAMKNB010000239          209 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.245, whole genome shotgun sequence.
ACCESSION   DAMKNB010000239 DAMKNB010000000
VERSION     DAMKNB010000239.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 209)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 209)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..209
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.245"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            73..>209
                     /locus_tag="PC494_003739"
     CDS             73..>209
                     /locus_tag="PC494_003739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF3914142.1"
                     /translation="MLQIKNLSKSFPNPYGEPNTIFENLSIDIEDGEFVSIIGSNGTG
                     KS"
BASE COUNT           91 a           25 c           32 g           61 t
ORIGIN      
        1 taaatatttc actaaaaaaa aacaaatgca aagctagtac caaaaataaa tcagaaaaaa
       61 gaggtgttgt agatgttaca aattaaaaat ctttcaaaga gtttccctaa tccatatggt
      121 gaacctaata ctatctttga aaatttatca atcgatatag aagatggtga atttgtaagt
      181 atcataggta gtaatggaac tggtaaatc
//
LOCUS       DAMKNB010000240          206 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.denovo.246, whole genome shotgun sequence.
ACCESSION   DAMKNB010000240 DAMKNB010000000
VERSION     DAMKNB010000240.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 206)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 206)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..206
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.denovo.246"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            complement(<1..167)
                     /locus_tag="PC494_003740"
     rRNA            complement(<1..167)
                     /locus_tag="PC494_003740"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT           52 a           55 c           39 g           60 t
ORIGIN      
        1 ttatcccgta ttagcatacc tttcggtatg ttatccgtgt gtacagggta ggttacccac
       61 gcgttactca cccgtccgcc gctctttacc gaagtaaatc gctcaacttg catgtgttag
      121 gcacgccgcc agcgttcatc ctgagccagg atcaaactct caaataaaag tttatcaggc
      181 tcagatacta ttgttatcaa aatatc
//
LOCUS       DAMKNB010000241        51368 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.guided.020, whole genome shotgun sequence.
ACCESSION   DAMKNB010000241 DAMKNB010000000
VERSION     DAMKNB010000241.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 51368)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 51368)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..51368
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.guided.020"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            158..1564
                     /locus_tag="PC494_003741"
     CDS             158..1564
                     /locus_tag="PC494_003741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HDF3914143.1"
                     /translation="MNTGFPKDFLWGASSSAFQVEGAWDKDNKGKTVADYNSFKKSHL
                     QADTKVASDFYHNYEEDIELMKELGMKTYRFSISWARIIPDGEGEINQKGLDFYNKII
                     DKLIECDIEPFVTLYHFDLPFKLVEKYNGWESRETVYAFERFAKICFKHFGDRVKYWQ
                     PHNEQNLIVRVEERINIYDETDSWKIDKMRAQMDYNLCLAHALAVNACHEMIKESKIG
                     AAVSSSVTYPLTSKPEDVYAARMNDNFKVYYMLDMHHYGEYPGYYMKYLEKRNIVPHM
                     EDGDKEILKKAKMDFIAVNYYRTNCAEALPEDSQHPFGLREGTVDFSMYGLFKMSMNP
                     NLEASEYGAAIDPSGLRVALNEYWQRYHLPVIITENGLGAKDILEDGKIHDDYRIDYL
                     RSHINACKLAIEDGVEMIGYCPWSFTDLLSSSQGFNKRYGLVYINRTDHEVLDLKRIK
                     KDSFYWYKEVIENNGIVK"
     gene            1592..2440
                     /locus_tag="PC494_003742"
     CDS             1592..2440
                     /locus_tag="PC494_003742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HDF3914144.1"
                     /translation="MYITKVLNNSLLLAKDDNDEEIILMGKGIGHNYKAGSELNKKDI
                     EKIFVLHDENIKKSIIQLATEIDAEYFGIAQMIIAYGIEKYNLKLMNHIYLALTDHIA
                     FAVRRFKEGIMIENHYLFEIKEFNPKEYDIGKYAITVFKEVLGLDLPEEEIGNIAGHF
                     INAQQDNPYSDRNKRSAKIVNAILQIVHYHFSIVYNKESFYYRRFVMHLKAFSQRFLA
                     NEPSREKIDFIYEQVQKNCKEEYECVKKVGAYMYKEYSRELPRQEELYLMIHIHKILG
                     ELCENS"
     gene            3101..3793
                     /locus_tag="PC494_003743"
     CDS             3101..3793
                     /locus_tag="PC494_003743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003020373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF3914145.1"
                     /translation="MNKVLIIDDDKDLCILLKKSISIEQIEANYCHSGRDGLAELSKQ
                     DYQLVVLDVMMPGMDGFETMEQIRKYSSIPILMLTSKSDNYSKVHGLRAGADDYLTKP
                     FEITEFTARVLSLIRRYTRFNPKNEEPQQLSFKGLLIDLDQHTVTTNGEPMLLPPKEF
                     GVLLYCAKHQGKILTKQQIYEAVWGEPYVYDDSNIMAIISRLRKKIELDPSSPIYLQT
                     IKGIGYQFNTEV"
     gene            3790..4725
                     /locus_tag="PC494_003744"
     CDS             3790..4725
                     /locus_tag="PC494_003744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF3914146.1"
                     /translation="MKMDEQTIILFLLLLSIGLLFLSIFAFSKLGHIYKRLKDIEEIL
                     ADVQIGDENRKILIKPCDVMAPLVYQLNEIVYDYENKLLSLKKSDKASKQLMTSLSHD
                     VRTPLTTLIGYLDAVHSGIVIEQEREEYLEIARRRAYDLKDYIDVLFDWFRLNSDEFT
                     LSIESVEIAELSRNILKDWIPIFHEKKLNFEIDIPENRLMVNLDPDGYSRVVNNLVQN
                     VLAHSKARQIKITMSEDSRMVLLRVEDDGVGIARENLPHIFERLYKCDKGRSEKGSGL
                     GLSIVSQMVERMGGQISVESEIGKYTIFTVSLPLI"
     gene            4873..5796
                     /locus_tag="PC494_003745"
     CDS             4873..5796
                     /locus_tag="PC494_003745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013273760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF3914147.1"
                     /translation="MNNLIIETKNLTKQYGAQKSVSNLNIHVQKGRIYGLLGRNGAGK
                     TTTMKMLLGLTKPTTGEIKIFGQDIHNNEKKLLPRIGCLIESPGFYPNLTGTENLKIF
                     ARLRGIPKKNAVESALDVVGLPNNDKKLFSQYSLGMKQRLAIALAIMHDPQLLILDEP
                     INGLDPIGIAEVRTFIRDLCTERGKTILISSHILSEIALLADDIGIIDHGILLEEESL
                     AQLEEKNSKYIHFAVSDAAQAARLLETQLNLKNFKVADNYNIMLYDTDVSVAEINRAF
                     ILNNIEVSESHLCEDTLEDYFKKVTGGEGIA"
     gene            5780..6550
                     /locus_tag="PC494_003746"
     CDS             5780..6550
                     /locus_tag="PC494_003746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF3914148.1"
                     /translation="MKELLDIISCEFSKLKRLKFILISILGACLFPIPATILIAKDNL
                     PFEQLFKLVVNFGYFLLLPIVLSIVASQLFFIERDNDVLKNLATVPVQKGKLALAKLA
                     VLLFISLFYSVAGLGATIIGGFIVGIVEGVAVKLGMSIAFGIMFFVTVLPVVVLIVYF
                     NRSYIFSIILSFVYAIFNFSISLNIINFEPNNPILSVLPAPVIMRWWMAFWGDPTGEY
                     TALRQPYLLSTPACVGILCLITIIAVLLICMIYKKQEN"
     gene            6560..7342
                     /locus_tag="PC494_003747"
     CDS             6560..7342
                     /locus_tag="PC494_003747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF3914149.1"
                     /translation="MLDIITTEFQKIKRYNILWIGVVAVLFSALLAVFQVVSSHGSDP
                     LTYESFANGVIWNNFSLSFPFGITLIGGYLINREYTDQTLKNILTVPISLRKLLVGKL
                     IAVGGITVLLSLFSFLCTFILGLLFCNINISVTLVVKSLVQILSVNLYCYVAVLPIIA
                     YFGRKQNAFLTGVGIAFVYGFCGVFVAGRNLTDFYPITAGLGLVGYNNGAGTVYQPLI
                     GAMTLIVILILTTILLVFTPNYDKVMTISKKKGIKHKKYSHK"
     gene            7718..8254
                     /locus_tag="PC494_003748"
     CDS             7718..8254
                     /locus_tag="PC494_003748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rubrerythrin family protein"
                     /protein_id="HDF3914150.1"
                     /translation="MNLKGTKTEKNLMAGFAGESEARNKYTYYASKARKEGYNQIAAI
                     FEETANNEKEHAKLWFKLLHDGMPSTEENLKDAAAGENYEWTDMYAKFAKEAREEGFD
                     KIAYLFEAVGKIEKEHEERYLKLLENLNEGKIFKRDEEVVWQCQNCGHVYVGTEAPEK
                     CPVCDHPKAYFNIKAENY"
     gene            8286..8675
                     /locus_tag="PC494_003749"
     CDS             8286..8675
                     /locus_tag="PC494_003749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HDF3914151.1"
                     /translation="MKFSKQRELILNEILNNPVHPTADYLYENLKKDNPNLSLGTVYR
                     NLAQLTEHGFIRKVSIPGYPDRFDGRIDNHYHIICEVCGEVYDLESEVLNNLQELISE
                     ETDIKITSYNISFKGICNNCKRCSQVG"
     gene            8712..9098
                     /locus_tag="PC494_003750"
     CDS             8712..9098
                     /locus_tag="PC494_003750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="desulfoferrodoxin"
                     /protein_id="HDF3914152.1"
                     /translation="MCSEQKFFICETCGNLVGMIQSGGVPIFCCGKPMKELVPNTTDA
                     AVEKHVPVIEVDGNNVTVKVSSTTHPMTKEHHIAWVYLMTEQGGQRKCLAVDGEPVVK
                     FALNDDDKVISAYAYCNLHGLWKAEL"
     gene            9225..10667
                     /locus_tag="PC494_003751"
     CDS             9225..10667
                     /locus_tag="PC494_003751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HDF3914153.1"
                     /translation="MSIYKCSVCGYIYDESKNDKTWDELSEDWECPVCTKGRSYFGKI
                     STVYYEEDEKIAEDIVEDESKLNTEKEGDLNYLSTYLRRDDEVEKHMDIIHEMAVTGK
                     SIIEPMRTKLPVISWDDILIMGAQLNPLPLNEHDEVNTTTIIGKKAKKPMIIENPVYI
                     SHMSFGALSKELKIALAKGAAQNKTAMCSGEGGILPEEKEASYKYIFEYVPNKYSVTE
                     ENLKNSDAIEIKIGQGTKPGMGGHLPGEKVTEEIAKVRNKPVGQDVISPSCFEEIQSK
                     EDLKKLVDELREVSEGRPIGVKISAGHIEKDMEFIAYAKPDFVTIDGRGGATGASPKL
                     LKDATSIPTIFALYRARKYIDTHGLDIDLVITGGLRISTDFAKAIAMGADAVAIASSA
                     LMAAACQQYRICGSGKCPVGVATQDEELRKRLHIENSANRVANFLNVSLEELKTFART
                     SGHKDIHDLSVDDLYTVNSEISNYTNIQHV"
     gene            10964..11779
                     /locus_tag="PC494_003752"
     CDS             10964..11779
                     /locus_tag="PC494_003752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HDF3914154.1"
                     /translation="MERLKIQVLVDNNTYIDRYFVGEPAVSYYIEIDGNRILFDSGYS
                     DVFISNAEKLNIDLGNLTHVVFSHGHNDHTRGIQFLENRYDLSTIELISHPNCFIPRK
                     HGEKSIGAPFSAEEIKNIFMYNPKDKPFNLSKNCVFLGEIPSINDFEKRAKIGKCKIG
                     DLWEDDYVLDDSAIVCKTDKGIFIITGCSHSGICNIVEYAKKVCRDDRVIGILGGFHL
                     FELNNRLDSTIQYLDKEEIRMLYPCHCVSFKVKAKMNEILNINEVGVGLTISI"
     gene            12381..13565
                     /locus_tag="PC494_003753"
     CDS             12381..13565
                     /locus_tag="PC494_003753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3914155.1"
                     /translation="MQKSVKKAKVTGSMLAIFGVASVLFSSHAGGGFATGNQETQYYV
                     QYGWTAPLMAILAMIILTATMREVIIMYNNNNCRNYKDLFCELWRPYPKLEIIWEIYY
                     YLMVLIAVSAVIAGAAAVFQSIGVNYFVAVFIIGVVLLVFTIFGAMLVSKAATAMTIA
                     ILVCTLTIFIVGIKAKVPEITEILSNRTSFTPGYIKPILNTFIYAGFQSVVIPTLAGC
                     SRPLLKNSKEATKAMIISFVMNAIALGLAVTMLMGWYREIIAAGQTTLPTLYVAGQSG
                     NHTIYIIYNVALFLCLMSTGVTTIFGLVNRFEDHKALSFLSSRMKRRVFTACAIMVVS
                     MLISLTGLSNIVKYGYGYCGYLGLFTIVIPFLTLGHYKNKKFAKENPEAKWPAELNEN
                     VN"
     gene            complement(13942..15051)
                     /locus_tag="PC494_003754"
     CDS             complement(13942..15051)
                     /locus_tag="PC494_003754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HDF3914156.1"
                     /translation="MDFKSLGISENTINILKKLGITTPTPIQKESIKLIKEGKDVIAE
                     AQTGTGKTLAFLLPIFENISLDINDIQVLILSPTRELAIQITEEAMKLKESKDVSILA
                     AYGGKDIGSQIKKLKGNIHMIIATPGRLLDHLNRKTIDLSKLKTFVLDEADQMLLMGF
                     KNEVEAILKETSNKKQTLCFSATINSQVKKLAYRYTKNPVVVSIQKEEITLNNIKQEV
                     VETTDRKKLDALCKVLDEDNPFMAIIFCRTKRRVDHLEEALAIRGYNCQKLHSDIAQS
                     KRERIMKSFRSLDIQYLIATDVASRGLDISGVSHIYNYDLPETPEDYIHRIGRTGRAG
                     EEGYTCAFIDPKNERMLSEIETAIESKISRRIIEL"
     gene            15514..16707
                     /gene="nifV"
                     /locus_tag="PC494_003755"
     CDS             15514..16707
                     /gene="nifV"
                     /locus_tag="PC494_003755"
                     /EC_number="2.3.3.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homocitrate synthase"
                     /protein_id="HDF3914157.1"
                     /translation="MCVISKDRAKEIKIVDTTLRDGEQTAGVVFANREKIMIAEMLSD
                     LGVDQIEVGIPTMGGDEKNVIKHICSRNLKSDIMAWNRAVIKDVEESISCGVDAVAIS
                     ISVSDIHIENKLRTSRGWVLENMAKTVEFAKKNGLYVSVNGEDASRADIDFLTEFINV
                     GKQAGADRFRYCDTVGVMNPFSIKNAIETLYERTNFDIEMHTHNDFGMATANALAGIA
                     AGANYVGVTVNGLGERAGNAALEEVLMALKCVYKCDLNNIDTRKFRGICEYVAQASGR
                     ILPTWKPVVGDNMFIHESGIHADGALKDPHNYEPFDPSEVNLERKIVIGKHSGRAAVV
                     NKLSEYEMYISPENATKLLNAIRATSIRLKRSLMDKEILQLYCDILAHEKGTTEEEAV
                     RGSYI"
     gene            16732..18657
                     /locus_tag="PC494_003756"
     CDS             16732..18657
                     /locus_tag="PC494_003756"
                     /EC_number="4.2.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aconitate hydratase"
                     /protein_id="HDF3914158.1"
                     /translation="MGDNIVYKIIKKHIVDGEAVAGSSIGIKIDQTLTQDSTGTMTYL
                     QLEAMGIDKVKTKRSVAFVDHNMLQQGFENADDHKYIQTVADKYGVYFSKPGNGICHQ
                     VFLERFSTPGDTLLGSDSHTPTAGGVGMMAIGAGGLDVALAMAGGAYYIKAPKVCKVN
                     LVGKLNNMVSSKDIILEVLRKQTVKGGVGKVYEYGGEGVKSLSVPQRATITNMGAELG
                     ATTSIFPSDEKTLEFFKSQGREDAWVELKPDADAVYDEEITINLDELKPLAAKPHSPD
                     NVDEVENIGKIKIDQVAIGSCTNSSYEDLMKVAQILKGNKVHKDVSLVIAPGSRQVME
                     MIARNGALADIISAGARILENSCGPCIGMGQSPGTDSVSLRTFNRNFYGRSGTLSAQV
                     YLVSPEVAAVSAIKGVLTDPREFDIKFTNLDVNEFLIDDSMIIKPADVGSDVEVVRGP
                     NIKPFPLNTELSQSIGGKVILKTEDNITTDHIMPSNAKLLPFRSNIPYLANYCFNTVD
                     TEFPQRAKDNNGGFIVGGDNYGQGSSREHAALAPLYLGVKGVIVKSFARIHKANLINS
                     GIIPMEFCDEKDYENISLLDNLEIPNILDNLGSGILEVKNTTKGTSFKVKVELSAKEV
                     DVLKAGGKLNYTKNQAN"
     gene            18679..19674
                     /locus_tag="PC494_003757"
     CDS             18679..19674
                     /locus_tag="PC494_003757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isocitrate/isopropylmalate dehydrogenase family
                     protein"
                     /protein_id="HDF3914159.1"
                     /translation="MYKVTLIPGDGIGPEVAKAMKKVVEATGVEIEWEEVNAGEAVIE
                     EYGTPLPEYIIDSIKKNKIAIKGPITTPVGKGFRSVNVTLRQALDLYVNLRPIKSFKG
                     IKSRYEDVDLVVVRENTEDLYAGIEHKIGDYAAESIKIITRSASERIVDFACNYVKDN
                     KRKKVTAIHKANIMKMSDGLFLDVFREVASKHGVEYDDLIVDAAAMNLVLNPENYDVM
                     VMPNLYGDILSDLGAGLVGGLGIIPSANIGKDCAIFEAVHGSAPQIAGQNKANPTALI
                     QSSVMMLRYLGEYENAQKIETALEKVFLEGSKLTVDLGGSASTTEFADEVCKYIV"
     gene            20000..20473
                     /locus_tag="PC494_003758"
     CDS             20000..20473
                     /locus_tag="PC494_003758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HDF3914160.1"
                     /translation="MVVSVEVCLIKTLDSNILREVGTLSRAVNSINDIKYKELKLQKG
                     QFTFLTRICENPGINLVELSNMLKVDKATTTKAIQKLIKAGYVDKKQDEFDKRGYNLT
                     PTDKSLEVYELIIEEENRSIEICFDNFTDEEKQVVTKLLEKMSKNVENEWFKVKR"
     gene            20507..21001
                     /locus_tag="PC494_003759"
     CDS             20507..21001
                     /locus_tag="PC494_003759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDF3914161.1"
                     /translation="MIRKANMNDLESIMKIIKSTVEEMKTYNNTQWDENYPLEKDFVS
                     DIKKQDLYIYEVDGEVAGFICLNYEEPEEYLGLNWSSNKKAMVIHRMAVNPNFRKTGI
                     ASKLVDFAEKLAVENNVSYLKSDTYSINSKMNLLLTKCGFIKIGEMSFLGKEKSFYCY
                     DKIL"
     gene            21098..21619
                     /locus_tag="PC494_003760"
     CDS             21098..21619
                     /locus_tag="PC494_003760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase"
                     /protein_id="HDF3914162.1"
                     /translation="MIGFLKKRRSIRKYKDVEVEKEKLDKILKAALLAPSSKGLRTWE
                     FIVVDDKEKLINLSQCRTKGGGFFLKNAPLAIVIIADKEKNDVWIEDASIAASYIQLQ
                     AHELGLGSCWIQVRNRMHDDNIEADKYIREELKVPSKYSVECIISIGYPDEEKKAYSD
                     SDLDYKKVHFNNF"
     gene            21808..22119
                     /locus_tag="PC494_003761"
     CDS             21808..22119
                     /locus_tag="PC494_003761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HDF3914163.1"
                     /translation="MGIFKTKMDEDWKVNYIKEFNEMRDSYESKLQKKQFEVDSLKSE
                     LDRLRSYKNSLKPKEKQITDDDINNIKSLRRDGLSYKEISNQTSWSKATVSRVLNGLY
                     D"
     gene            22147..22833
                     /locus_tag="PC494_003762"
     CDS             22147..22833
                     /locus_tag="PC494_003762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HDF3914164.1"
                     /translation="MKYSYKKCIIDSILLMFIVQILRMILNYVLLSQFEFTLENFNII
                     NLISFTLVGLSLILFLKDNSLYNKVRNRKITEAFEENKNNILIEKCKLILFVVVLSLA
                     IIVTYCTKGYVLFNVTMMTLSVLIVPIFEELFFREYIWNYLSNFIKSKSKIICITSIL
                     SGIYNIGYIDVIRNYVILYNNSSYTFEVIISKIMIGTVFGIVLGLVKYRFRDVGFCIL
                     LRSLFAIFIR"
     gene            23065..23949
                     /locus_tag="PC494_003763"
     CDS             23065..23949
                     /locus_tag="PC494_003763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fumarylacetoacetate hydrolase family protein"
                     /protein_id="HDF3914165.1"
                     /translation="MKFVTFCSSNEEKIGVFNSETNSIYEINSLGLSKLYTDMNNFIE
                     NVSTGDLEKIKNNSFENAKCYKLEEVKLCSPIVRPKKDIICLGLNYKDHVNEIPDGVI
                     KNVVMPDYPIYFSKRADKIIGVDDKISLHGDLVEKLDYESELAVIIGKEGINISKEDA
                     YEYIFGYTIVNDISERALQDKHVQWFRGKSLDTHTSMGPYIVHKEEFEHPLKLDISSV
                     VNGEVRQNSNTEYFIFDIPTIINDLSRGMTLKPGDIISTGTPAGVAMGMNPQVYLKHG
                     DIVECKVEGIGVLKNIVD"
     gene            24048..25223
                     /locus_tag="PC494_003764"
     CDS             24048..25223
                     /locus_tag="PC494_003764"
                     /EC_number="2.1.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolecarboxamide
                     formyltransferase"
                     /protein_id="HDF3914166.1"
                     /translation="MARELELKYGCNPNQKPSKIYMKNGELPIEVLNGKPGYINFLDA
                     FNSWQLVKELKEATGLPAATSFKHVSPAGAAVGVPLSDTLKQIYFVDDLELSPLACAY
                     AMARGADRMSSYGDFIALSDVCDKETATIIAREVSDGIIAPGYTDEALEILKGKRKGN
                     YNIVKIDENYTPEPIETKDVYGITFEQGRNEILINEDLLKDIPTDNKIFTDSAKRDLI
                     IALITLKYTQSNSVCYAKDGQVIGVGAGQQSRIHCTRLAGNKADTWYLRQHPKVLNLK
                     FKKDIGRPDRDNTIDVYLSDDYMDVLADGIWQNFFEEKPEPLTGEGKRAWLKTLTGVA
                     LGSDAFFPFGDNIERAKRSGVSFIAQPGGSIRDDNVILTCNKYNIVMAFTKNRLFHH"
     gene            25351..26205
                     /locus_tag="PC494_003765"
     CDS             25351..26205
                     /locus_tag="PC494_003765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3914167.1"
                     /translation="MALNIRNYSLLCNQGTAKFNEDVVGINPFGAWVLDGATGLNGKN
                     LVSTESDARWYVQWWNRYLYKNINKEESLKSIINTGIIEVKKEYELRLNGFKVEKLDL
                     PSSSIVVVKFHENKVEYFLLGDCALFIKNGDSKVIKDRSICKFDNTVFDEMSKLSNLE
                     EMAFDEIRTSVMDTIVSNRLKKNTKEGYWILDFDEEAVENSIYGYIEIKKDFQLMLTS
                     DGFTSACDRYNLIKEEELIRIAEKFGIGYIHNKVRDFEDNDYKAVKVPRFKVKDDSSC
                     LYLDIYND"
     gene            26249..27484
                     /locus_tag="PC494_003766"
     CDS             26249..27484
                     /locus_tag="PC494_003766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HDF3914168.1"
                     /translation="MKILHIITQKPNSTGSGIYLSGMIKGFEKIGHKQAVIAGIDVND
                     DVNCFPSEVSFYPVKYNCGELNFPVVGMSDSMPYESTRYKDLNIDMINRLKYQFKVNI
                     DKAMNDFKPELIICHHLYLLTAFVREMVKDIKVMSICHGTCLRQLNTIDLEKEYIIAN
                     IRKLDLIFALHENQKYDIIKTFGVSESKVVVIGSGYNDDIFYNKNYKIKDDKIKIVFA
                     GKICKSKGLIPFIKAISKLKYSKDLIEVNFAGTGSDIESYNEIVKLASKSPFKMNFLG
                     KLEQRDLAELFNRSQIFVLPSFYEGLPVVVLEALSCGTDVITTDILGVKEWIGSEINN
                     SGKIEYISLPFMEKEGIPKDEELYDFENNLYNAIDSKIQSLLNNSNKKTSVDMSKKTW
                     DGLAYRINEVILMDELCLV"
     gene            27585..28526
                     /locus_tag="PC494_003767"
     CDS             27585..28526
                     /locus_tag="PC494_003767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp25"
                     /protein_id="HDF3914169.1"
                     /translation="MRISKKVLALGISALLLSVSFPTSINALDKIENIQGVDKYETAG
                     LISDKQDFTTAVLINADSTMVDGIAASGLAGVNNAAILLTNKDDIPEATLQRLNRVTK
                     IYVIGGENSISKDVEKMLLMRRMQVIRIDGVDRVDTSYKIAGEIEKIKNSDKMFLVNG
                     FKDEADAVSVASVAYRDGAPIILTKDIPSAEEDTDLDPWFGVSPVPVYAIGGESTLSD
                     YIVSRYRATRIGGVDRYQTNKNVIEKFYNGAKEFYITSGDDLVYALVASPLAKNAPVV
                     LVSNKSDKSILSGASKVTAIGISDKSIIEQCLDAVKK"
     gene            complement(28577..28936)
                     /locus_tag="PC494_003768"
     CDS             complement(28577..28936)
                     /locus_tag="PC494_003768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3914170.1"
                     /translation="MDLFEVNIVLNSGTAGGMNPKLKIFNMVISTEVCHHDVTQDTLT
                     EFHSWLKTVFFEANCELIKISEMAVKKTNQEETVFWGRILAGEAFITNKGRKKINEKE
                     AYLHLIASSHIFYTIIK"
     gene            complement(28962..29426)
                     /locus_tag="PC494_003769"
     CDS             complement(28962..29426)
                     /locus_tag="PC494_003769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF3914171.1"
                     /translation="MNLGNSLFQARKKHGLSQEDVAEKLGVSRQTVSKWETDETVPDI
                     RQSKKLAILYNVSLDELIDFDIDMEEIQEAINKTSEETEEKINWTNAWGKKYPILLKY
                     QTDVNISNYAYKVNMMLDELKQEYQYNELEAMLILKDILYNVWKNRKSKRKQ"
     gene            complement(29594..29802)
                     /locus_tag="PC494_003770"
                     /pseudo
     CDS             complement(29594..29802)
                     /locus_tag="PC494_003770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004071281.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3788 family protein"
     gene            complement(29846..30199)
                     /locus_tag="PC494_003771"
     CDS             complement(29846..30199)
                     /locus_tag="PC494_003771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HDF3914172.1"
                     /translation="MDRKRELKQLYKEMKFDTGVFIIKNDITKKIYLGKSNDIKSKFN
                     SLKFQLGAGSCMIKELNNEWKKYGEKAFTFEVLELIKHDDNKTEKDYLEELDILEMVW
                     LEKLKEDNTYEIYSI"
     gene            30495..31406
                     /locus_tag="PC494_003772"
     CDS             30495..31406
                     /locus_tag="PC494_003772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CGNR zinc finger domain-containing protein"
                     /protein_id="HDF3914173.1"
                     /translation="MNKKIELIGNFASDWIRYSDYEYKITEEDELYIVPTEDAVFTMY
                     NPFDVADDIIVDIIRIGQEALQDISKETKEMKLKKEILEFVKKYGLLGLIYSSVYNRD
                     IVGEERVLMIEKNYITKENILSTDEYVNMFIPFASDEDVYFKKYRRGIDVSKREESPK
                     FFGKRPLILDLVFSKFYTEQLDWIVSFAKDMCKHFNQICVYKNTSNLLTESVTIMSGG
                     FNPQKIGFSISQLDKPIIAWEFDSLKTAIETIYAFAITSEPSSLNKCKYCGKIYIPTN
                     SKSQYCSPSCRNCSNVKKSRSRAKKDK"
     gene            31667..32101
                     /locus_tag="PC494_003773"
     CDS             31667..32101
                     /locus_tag="PC494_003773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3914174.1"
                     /translation="MISPIILSSINQNLKEIERNELLETNIESGDYGLALSESDVKDI
                     INSRDNTLKGYGRIELDIKVTKQLIENIYTSQYTNVDNYLEAINDMQEIFYYLKNETD
                     DKICDDEIIEILGDFYEKFSGNMDNVRGEADEFAKKFKFGEV"
     gene            32124..33659
                     /locus_tag="PC494_003774"
     CDS             32124..33659
                     /locus_tag="PC494_003774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3914175.1"
                     /translation="MLNNLSNININENNLIKNQYSISLLKECLNCKVIDEREVYNIQQ
                     EISLILMDLIKKYTNGQSTSVKTEVAEKLLISIWYAIDAYINKLGDIEKRVVELTAKN
                     VKKVYLGGIEILEEELVRLKDFYKLMMSRKLDTNSIAYNDTLMELSSFFKSYIVKFEA
                     QDVPVSIDYPLALDDMDVKGIYYVKNYIESIDIENRFCNLFKKKDREKLFYDYGVTYK
                     IDCDVILVNLFELIMNNCIFSTILGNEVTNLEISKYEYEFLEKQFKNMYNNITEDKVI
                     DSEESNIIELIEVDDSFNTEVDSNLDYNDFEEINREIRINKKITLLLMEAIEVLIKRL
                     SIEDEDVIRYIKKYEKIFIESVLSSIKSNTFKSMVTVSKNKNEHLEDYIVDDESKLDD
                     ESFREIFNEILDSTSIIEKIRIIKENINAKKDFIDILESECLFGEEYLMLFASLSELE
                     LAILGSVVFYEDIRMREINILEFMLNEKTETTLWKIEYIKFMKRQSEDKIYSIEEHMN
                     KIN"
     gene            33743..35110
                     /locus_tag="PC494_003775"
     CDS             33743..35110
                     /locus_tag="PC494_003775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HDF3914176.1"
                     /translation="MKEYIINNVEEIREELIDLSKKIWENPELAFEEKYASSIQKEYL
                     KSKGFKIEEVENLPTGFIASFGEGKPVIGILGEYDALPELSQCVSAERKPLVEGKAGH
                     GCGHNLLGVAGVGAVVSIKKLIEENKFNGTIKYFGCPAEEEGGGKTVMCINGCFDDVD
                     CAFTWHPFDINAPWRGGSLANLSVKFKFKGITAHAAQAPHNGRSALDAVEIMNVGANY
                     LREHVIDSIRMHYVITNGGGRPNVVPGFAESWYFIRGKKAKDAEHVLDRLIKVAQGAA
                     MMTETEMEYKVTDGIYDYIPNQCLTDLVYDNMVFVGCPKNTPEEEEFAKKLCDTLTRE
                     ERLGVATSLQNDKSIVESYIHKEIVDGDKDKGLAGSTDVGDVSYVIPVAQFAMAAWPV
                     GIASHTWQSCSSAGSNIGFSAMINSAKVLACSAYDVFMDTKIIDEAKIEFDKSLDGQK
                     FKPLV"
     gene            35145..35369
                     /locus_tag="PC494_003776"
     CDS             35145..35369
                     /locus_tag="PC494_003776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NifU family protein"
                     /protein_id="HDF3914177.1"
                     /translation="MREKVEKVLEEKIKPVLQRDGGDVELIDVNENGVVLVRLQGACS
                     GCPGATMTIKAIIENVLVSEVPGVTQVLGV"
     gene            complement(35817..36215)
                     /locus_tag="PC494_003777"
     CDS             complement(35817..36215)
                     /locus_tag="PC494_003777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03987 family protein"
                     /protein_id="HDF3914178.1"
                     /translation="MNYKLILAIVFITSALIFYTIGVFGERKAKILKKKHVIIFWLGF
                     IFDTLGTFTMSNIANSHTFEVKSALSQNLHSITGLLAIVLMLFHASWATFVLYKDDEE
                     KKKFFHKFSIVVWTIWLVPYFIGMFIGMAG"
     gene            complement(36218..36619)
                     /locus_tag="PC494_003778"
     CDS             complement(36218..36619)
                     /locus_tag="PC494_003778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HDF3914179.1"
                     /translation="MLLKELYSKTMYTVEENFKENGLTHQQIIVIKLIAHNQELTISQ
                     LCDEMSLAKGTVSGIISRLEQIGYIEKFKKSNDKRNTYVKFTTTGFEFATNFKIKMQE
                     SFDDIFKNCDENELSDLVKNLRNILAKVKER"
     gene            36979..37965
                     /locus_tag="PC494_003779"
     CDS             36979..37965
                     /locus_tag="PC494_003779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF3914180.1"
                     /translation="MLKDILKKLLQFILVMFLLSFIVFYMARLAPGDPLISYYGDGVE
                     RMSTQEKENAMKKLGLDEPIYSQYIKWISNASKGEFGISFKYKQNVTSVINDVYINTI
                     ILGGSGYILTFVLALLLGIFCTLHEDKLIDRIICKLGTITNCIPSFWVALVLILIFSI
                     NLSILPSSGAYSMGEESSILSRISHLILPLTVLILSHLWYYTYMIRNKLLEEIREDYV
                     LLCKAKGLNNRTIVFKHCLRNIMPSYISIMAISIPHILGGTYVVEKVFSYPGLGTLCF
                     ESAKYHDYNMLLVLCLITGALVVFGNMLAQIINNKIDPRMKYDRGDTNEATI"
     gene            37949..38860
                     /locus_tag="PC494_003780"
     CDS             37949..38860
                     /locus_tag="PC494_003780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF3914181.1"
                     /translation="MKPQYSDFEIVGENYILVAEDEHIETKKTLSKKIKELPYISIII
                     LSIIVIGSVFSSFIMTHEPTYMDLASSNLAPNKTFLFGTDSMGRDIYSMIWYGGKISL
                     FIGLFSTVISTVIGIVYGSISGSASELVDDAMMRFTEIILSIPSILIIIFVQAILGNS
                     NPVSMSIVIGITSWMNISKIVRTEVRQIKNSEYILAAKSMGGGFFYVLKQHLLPNFVA
                     SIMFMVVTNIGAAIGTESTLSFLGIGLPIEIVSWGSMLSLSEEALLSNRWWIILIPGI
                     FLVTTLVCITNIGNYIRKNNNKKSSNL"
     gene            38973..40541
                     /locus_tag="PC494_003781"
     CDS             38973..40541
                     /locus_tag="PC494_003781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDF3914182.1"
                     /translation="MKLKKLKVLSLVMILSLMAGCSSGGDKDKKADTPKDGKVLVYGS
                     NDYTSINPALYEHGEINSLIFNGLTAHDENNKVVPCLAKDWKFDEATNTYTFNLRDDV
                     KWHDGEKFTANDVKFTIETIMNPDNASEIASNYEDITKIDVVNDNTIKITLKAPNTAM
                     LDYLTVGVLPKHALEGKDIATDEFNQKPIGTGPFKLEKWDKGQSITLVKNSDYFVKEP
                     GLDKVVFKIVPDDKAKAMQLKSGELDLAQITPKDMSNFEKDEKNFKVNIMKTADYRGI
                     LYNFNSKFFKDKKAKGLPNALSYAIDRKAIVDSVLLGHGVPAYSPLQMGPYNNPDIEK
                     FEYNPEKAKQEIEKLGWKLGSDGIYEKEGTKLAFEITAGESDQVRVDMAKICAQQLKE
                     IGVDAKAVVVTETDWANQDAHLIGWGSPFDPDDHTYKVFGTDKGANYSAYSNPTIDKI
                     LQKARETEDKDEKLKLYKQFQVEMTKDMPYTFIAYIDAIYVGKPNIKGLTPDTVLGHH
                     GVGIFWNIADWTIE"
     gene            40616..41641
                     /locus_tag="PC494_003782"
     CDS             40616..41641
                     /locus_tag="PC494_003782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF3914183.1"
                     /translation="MEHLLEVNNLSVSFKVEEGEVQAVRNVSFNLKKGETLAIVGESG
                     CGKSVLCKSLMRILPYNGYIKNGEVLLKSSDLVKKSEKEMEDIRGKNISMIFQDPMTS
                     LNPTISIGKQIAEAVIIHQGISKSEAKKRAIELIELVGIDNPEKRFKQFPHHFSGGMR
                     QRIVIAIALACNPDVLIADEPTTALDVTIQAQIIDLIKDLQHKIGLSIIFITHDLGVV
                     ATIADRIAVMYAGKIVEIGTVEDIFYDPRHPYTWGLLGSLPTLDSQDDYLYNIPGMPP
                     NLLNPPKGDAFAIRNKNALKIDYEKEPPMFKINDTHSAATWLLHPDAPEVDVPVRVNC
                     GRVISNE"
     gene            41634..42578
                     /locus_tag="PC494_003783"
     CDS             41634..42578
                     /locus_tag="PC494_003783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009527644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF3914184.1"
                     /translation="MNREKILEIKNLKQYFHLDKSTTVKAVDDISFDIYKGEIFGLVG
                     ESGSGKSTTGKTIIRLHESTGGEVIYKGNCISDKKTYKFIKKDVNKSMQIIFQDSTSS
                     LNPRMTIADIISEPLKIQGICKNKTDRMNKVYEMLKLVGLDRSYANKYPSDFSGGQRQ
                     RIGIARALSVDPEFIIADEPIASLDVSIQAQIVNLFKKLQQEKNLTCLFIAHDLSMVR
                     HISDRIGVMYNGKLVELADSNELYNNPIHPYTKSLLSAIPVPDPRYAKSRNRIEYNSN
                     GYDCSNEKSLSWIEVSDGHFVYSSKSEINKYQQNLKVV"
     gene            42937..45594
                     /locus_tag="PC494_003784"
     CDS             42937..45594
                     /locus_tag="PC494_003784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDF3914185.1"
                     /translation="MIYKKDKVMKVLESSYRENEKGITANQLSEKTGIARNNISTYLN
                     QLFNEGMVTKIKGRPVYYIPANLNLNKNELLDTQSELLGIKKGTKVENKIKKDSFETL
                     IGKEHSLRPIIEKCKVAMLYPTNGLHTIIYGETGVGKSMIARYMYDYSIDSGIRKNKA
                     PFVTFNCADYANNAQLLMGHIFGVEQGAYTGAESSRKGLLEIANGGILFLDEIHRLPA
                     EGQEMLFTFIDKGTFKRLGDATKERESKVLIICATTENPTSTLLDTFNRRIPMKIEIP
                     SLRDRTMIERMELVKNFFKEESKSISISIKVHKEIIKSLLLYDCKNNVGQLQNDIKLA
                     VANGYLRYKRDNKEPVYIEKKYFDKSINEVSDDYREKSIKADEVITHGIEYFVFTSLG
                     EEEVINYNDINIINAVNTNLNKSVEMNIADASLFNNVKFKSMCESIRQIIKEDEEIDI
                     SESIFKSMAIYIKSVLDKSSSTNNIDLNQIRRNNRSEFKTALKIVGIIENEFDLFLSI
                     ETVAYITLFIVQAKQDEQNKIVNNINIIVAMHGETTASSMVKAVGDIIGKCSAISFDM
                     KLDKSYDEVIVDFKNLINNIDNKDVLLFTDMGSLNSFDEIIKKEKKCGVRVIPMVTTL
                     TVLEAVQKANMGLPLNDVYNSITNTRKYYFGTNEIQNKENLSKTIIIASHVSEGVDNK
                     TRKILEEKMSRYLDGIDIISVPYKTEKDLSLNITKLKESSNIVAVINEQRINIRGIDY
                     ISKKDIDKDENINKLKNIIKISIGYDDVVEGLKTSLKSSNYNRIFKGIKYVSDELFLV
                     FNIEKKYDKVIGLMMHLAFMVDGLIGNTREIEKLDKEKTLDYHKSLSKIKDIVSQLDK
                     KYNIEINEKECYQILLILEYAEIIEKDYQ"
     gene            45809..46438
                     /locus_tag="PC494_003785"
     CDS             45809..46438
                     /locus_tag="PC494_003785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3914186.1"
                     /translation="MQDKILRDKKANDPWARMTTRNGFSADEIISSFQKAIRRNMVEE
                     ACEFAYELYISSPELEDKLWRRILTISVEDIGMGDPSAVIIINNLNQVRKEYSYADGD
                     RPLFFIHAIRYLCACEKDRSSDLLKNIIIKGFAMGKVPEVMDVALDKHTYRGLEMGRD
                     SFHFLNEASIVIPEKEVDNDYKERYLKILEKYKQEEVIDTAFKFNHWQY"
     gene            46573..46899
                     /locus_tag="PC494_003786"
     CDS             46573..46899
                     /locus_tag="PC494_003786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDF3914187.1"
                     /translation="MNILLVCANGASTGVLVEKMKSFCSEHEKLKTKTINIEATSFEN
                     LKSYIEANDTDVVLVAPQIRFKEDDVVEACKNYKIAVGLIDTKHYGRMDAPSVMKSAI
                     ELYKNR"
     gene            46915..48204
                     /locus_tag="PC494_003787"
     CDS             46915..48204
                     /locus_tag="PC494_003787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDF3914188.1"
                     /translation="MEALQNNLRRFLLPIAQKIEKQRHLQAIKEGMISITPIIIVGSL
                     SMLFMALNNMLPEGSAKTLLSENMDTLLIPNKFTMSLLSIYSAFFIAQALAKKYNLNH
                     VEIGMTAVVAQLVVCGQVVDGVLDTSYLDAQGLFVSILVALLVVDITKFMNDKNLVIR
                     FPKEVPSVVNKSFRNLTPMIVCIMLFTAIAAITKNVSGQPLPAIIMNFLAPAISSVDN
                     VFAVTIILFITQLLWFFGLHGAAITSSIWMPIAATYMAENATLIAAGGDPKYVFTIGF
                     YYGFLQVTGSGITLGLVYLMSRSKCKSFNSMGKVVILPSLFGINEPVIFGTPIVMNPY
                     MFVPFVFGPVLVGALNFMALKVGLVGLPIAEPPGFLPPGVAAFLMTLDWKAIVLVFAS
                     IILMTLIYYPFFKIMEKEELNKNAELATTLDDDSFDF"
     gene            48228..48557
                     /locus_tag="PC494_003788"
     CDS             48228..48557
                     /locus_tag="PC494_003788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HDF3914189.1"
                     /translation="MVPEMEEKVFSIISEAGDAKSDVMMSLKEIKKGDYNKAKHLLNS
                     ASEKIQTASKHHLELLSNAMNSEDSGTDFLVVHSEDHYSNALFAHSLVSELVDIFEMM
                     DPRINKN"
     gene            48705..50033
                     /locus_tag="PC494_003789"
     CDS             48705..50033
                     /locus_tag="PC494_003789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010963854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-alpha-glucosidase"
                     /protein_id="HDF3914190.1"
                     /translation="MEKFSVVIAGGGSTYTPEIILMLLDNLDRLPLRAIKLYDNDEER
                     QNKVAKACEILIKEKDPNIEYLATTCPKEAYTDVDFCLAHIRVGKLEMRELDEKIPLK
                     HGVVGQETCGPGGIAYGMRSIEGVLENIDYMEKYSPNCWMLNYSNPASIIAEAVRRLR
                     PNSRVINICDMPIGMEHNIARIAGLKSRKHMDIRYFGLNHFGWYTSIKDKKGNELLPK
                     LVEHIKEYGFINGEEGMKNDKKDSWFETNLFTKEIVKTDLTTIPSSYLKYYLFPDYVV
                     NHSDVNYTRANEVIDGREKEVFGSCALIEKQGHSKGSGLKIGIHAEFIVDLATALAFN
                     TQERMLLIVQNNGAIENIQDDAMVEIPCIVGKDGYEPLSIGKIPTFQKGLIEQQLAVE
                     KLVVDAWIEKSYNKLWQALMLSKTVPSATVAKELLDDLIEANKNYWPKLN"
     gene            50350..51210
                     /locus_tag="PC494_003790"
     CDS             50350..51210
                     /locus_tag="PC494_003790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-ADP-ribose hydrolase"
                     /protein_id="HDF3914191.1"
                     /translation="MAMKWRDYADDVNLFEDFDKTIKPLTDEQRRKNINTLIAYFSKE
                     VPSKIYNLSNDEIKPRDILRGLLNVYPPKEIAPEILNMLHNLLLIECEERELIDVNDI
                     EEVEEGIAIWRGNITNLRADAIVNAANNKLLGCLQPLHLCVDNEIHSCAGPRLREDCD
                     KIIKKQGHLEYTGDAKITRGYCLPAKFVVHTVGPIVSGGQPSKEQEKQLLHCYKSCLN
                     TIKEIDEIKNIVFCGISTGVFGYPKKEAANLAVSRVRLWLKENPEKNLKVVFNVFTEE
                     EEEKYRRIFK"
BASE COUNT        19791 a         5693 c         9213 g        16671 t
ORIGIN      
        1 aatatagagt aagtttattg taatgaattg ttaaagaaaa taattaatat agggtaaatc
       61 tatctcaatg aaataacaaa gaaaagagtt aatatagagt gaacttattg caatgaatca
      121 acaaagaaaa taatcaatat aaaaaggaga aatatttatg aatacaggat ttccaaaaga
      181 ctttttatgg ggagcatcat cttctgcatt tcaagtggaa ggagcttggg ataaagacaa
      241 taaaggaaaa accgtagccg actataattc ttttaaaaag tctcatttac aggcagatac
      301 taaagtcgca tcagactttt accataatta tgaagaagat attgaattaa tgaaagaatt
      361 agggatgaaa acatatcgtt tttcaatttc atgggcaaga ataataccag atggtgaagg
      421 agagataaac cagaaaggtt tagactttta taataagata atagacaaac taatagagtg
      481 tgatattgag ccattcgtaa ctttatacca ttttgacctt ccatttaaat tagtagagaa
      541 atataatggt tgggaaagta gagaaactgt ctatgctttt gaaagatttg ctaaaatatg
      601 ctttaagcat tttggagata gggtaaagta ttggcaacct cataatgaac agaatttaat
      661 tgttagagtg gaggagagaa ttaatatata tgatgaaaca gattcatgga agatagataa
      721 aatgcgtgct cagatggatt ataatctttg cttagcacat gcattagcag tcaatgcatg
      781 tcatgagatg ataaaagaaa gtaaaattgg agcagcagta tcatcatctg taacatatcc
      841 tcttacttct aagccagaag atgtatatgc agctagaatg aatgataatt ttaaagtgta
      901 ctatatgctt gatatgcatc attatggaga atatccaggg tattatatga agtatcttga
      961 aaaaagaaat atagttcctc acatggaaga tggggataaa gagatactta aaaaagctaa
     1021 aatggatttt atagctgtaa attattatag gacaaattgt gcagaagctt tacctgaaga
     1081 ttcacaacat ccatttggat taagagaagg aactgttgat tttagtatgt atggactatt
     1141 taaaatgtca atgaatccta acttagaggc ctctgagtat ggagcagcaa tagacccatc
     1201 aggtcttaga gttgccttaa atgaatattg gcaaagatat cacttacctg ttataataac
     1261 agaaaatggt ctaggagcta aagatatatt agaagatgga aaaattcatg atgactatcg
     1321 tatagactat ttaagaagtc atataaatgc atgtaaacta gctattgaag atggtgtaga
     1381 gatgattgga tattgtccat ggtcatttac agacctttta agttcttctc aaggttttaa
     1441 taagcgttat ggacttgttt atataaatag aactgaccat gaagttttag atttaaaaag
     1501 aatcaagaaa gatagttttt actggtataa agaagttata gagaacaatg gaatagtaaa
     1561 ataaacataa atatatattg agggttttag tatgtacatt acaaaggtat taaataattc
     1621 gttgctactt gcaaaggatg ataatgatga agaaataata ttgatgggga aaggcattgg
     1681 ccataattat aaggccgggt ctgagttaaa taaaaaagat atagaaaaga tttttgttct
     1741 tcatgatgaa aatataaaaa agagcattat acaattggca acagaaatag atgcagaata
     1801 ttttggtata gctcaaatga taattgcata tggaatagaa aaatataact taaaacttat
     1861 gaaccatata tatttggcct taactgacca cattgccttt gcagtgagac gttttaaaga
     1921 aggtataatg attgaaaatc actatttgtt cgaaatcaag gaatttaatc caaaagagta
     1981 tgatatagga aaatatgcta ttactgtttt taaggaggtt cttggtttag acctaccaga
     2041 agaagagatt ggtaatatag caggccattt tataaatgca caacaagata atccttatag
     2101 tgatagaaat aagagaagtg ctaaaattgt aaatgctatt ttgcaaatag ttcattatca
     2161 cttttctatt gtatataata aagagtcatt ttattatagg agatttgtaa tgcatctaaa
     2221 ggccttttca caaagatttc tggctaatga accatcaaga gaaaaaatag attttatata
     2281 tgagcaagtt caaaaaaatt gtaaggaaga gtatgaatgt gtgaaaaagg taggagctta
     2341 tatgtataag gaatactcca gagaattacc aagacaagag gagttatatt tgatgattca
     2401 tattcataag attttaggag aattatgcga aaatagttag aatatcttaa tatgctagta
     2461 atattataaa aaattaaaaa ttaactacac tttaaatatg aataattgca ttacttaagg
     2521 gggttgtctt aaaattgatt tttttaatta aatttgaagc tcaactcctt ttttaaacct
     2581 ttatatcatt acaactttaa tgtttatacg cctgtacttc agatgtatat ctacttttta
     2641 catttctcaa catgcaaatc taccattttt tgcagtatgt taattgaaat aaaccattga
     2701 gttaacccta aatttattct ggacttatag gaatagttcc aaagatactt taaaatattt
     2761 tctggaataa ttgcttattt cacatatgtt ttattgtgat gttttgattt aataaattct
     2821 tcaactctgt atatagtaaa tgtattatca tgtttgtttt attcaagcac acttataata
     2881 cgcttgattt tttcacaatg atgaaatata ctaatgggtg ttataagtat aagaatagca
     2941 ttacacttga agaagcaagt gataaatgag gtataaatcc tcatatgata aactactatt
     3001 tcattgagga gcatattcta aatgatgtaa agatactaca atatgactaa attcctaatg
     3061 ataaaaaagt ctacgaatga gtgtagaaag gggaactaag atgaataaag ttttaattat
     3121 agatgatgat aaagatcttt gtattttgtt aaaaaagagt atctcaattg aacagattga
     3181 agcaaactat tgccattctg ggagagatgg actggctgaa ctttcaaaac aagattatca
     3241 gttagtagtt ctagacgtga tgatgccagg tatggatggt tttgaaacta tggaacaaat
     3301 acgaaaatat agcagtattc ccatcttaat gctgacatca aaaagcgata attacagcaa
     3361 agtgcatgga ttgcgagctg gtgcagatga ctatctaacc aaaccatttg aaattacaga
     3421 atttactgct cgtgtactgt ctttaatccg acgttacacc cgttttaatc caaaaaatga
     3481 ggagccacag caactttctt tcaaaggttt gttgattgac cttgaccagc atacagtgac
     3541 taccaatggc gaacctatgt tgcttccacc caaggaattt ggtgtgcttc tttactgtgc
     3601 aaagcatcag ggtaagattt tgacaaaaca gcagatttat gaagccgtgt ggggtgagcc
     3661 atatgtatat gatgacagca atatcatggc tattatcagt cgcctaagaa aaaaaattga
     3721 actagaccca tcatctccca tctatttgca aacaataaaa ggaattgggt atcaattcaa
     3781 cacggaggta tgaaaatgga cgaacaaacg ataattcttt tcttactctt gctgtcgatt
     3841 ggtctacttt ttctttccat atttgctttt tccaagcttg ggcatattta caagcgccta
     3901 aaagatatag aggagatact ggctgatgta caaattggag acgaaaatcg taaaatacta
     3961 attaagccat gtgatgttat ggctccattg gtttatcagc ttaatgagat tgtctacgat
     4021 tatgaaaata agttactttc tctgaaaaag tcggataaag ctagcaaaca acttatgaca
     4081 agtttatctc atgatgttcg tacaccatta acaactctga ttggttatct ggatgctgta
     4141 cacagtggta tagttatcga acaagaacga gaggaatacc ttgaaatcgc taggcgtaga
     4201 gcctacgacc tcaaggatta cattgatgtt ctttttgact ggtttcggtt gaactctgat
     4261 gaatttacgc tgtcaataga atctgtagaa attgcagagt tgtcacgcaa tattttgaaa
     4321 gactggattc ctatattcca tgaaaagaaa ctgaattttg aaattgatat tccagaaaat
     4381 cgactaatgg taaacctcga cccagatgga tattcccgtg tggtcaataa tctggttcaa
     4441 aatgttcttg ctcacagtaa ggctcggcaa atcaagatta ccatgagtga ggattccaga
     4501 atggtattac tccgtgttga ggatgatggt gttgggattg ccagagaaaa tttaccacat
     4561 atttttgagc gactgtataa gtgtgataaa ggacgttcag aaaaaggaag tggtcttggt
     4621 ctatctattg tcagtcaaat ggtggagcga atgggtggtc agatttccgt agaaagtgag
     4681 attggaaagt ataccatatt tacagtgagc ttaccattaa tataaaattg tttttccccc
     4741 atgtgacatg tatacacagg gggatttttt gtaagttata aagttgcaag gttaatacaa
     4801 ggttgttgca aggttaatgt aagattgagg tggtatgata actttaataa acaaaggagg
     4861 cttttattat ttatgaataa tttaattatt gaaacaaaaa atctcactaa gcaatatggt
     4921 gctcaaaaga gcgtttctaa tttgaatatt cacgttcaga aaggtcgcat ttacggattg
     4981 ctaggaagaa acggtgcggg taagacgaca actatgaaaa tgttattggg tctaacaaaa
     5041 ccaactactg gagaaattaa aatatttggt caggacattc acaataacga gaagaagctt
     5101 cttcctcgaa ttggatgttt gattgaatca ccagggtttt atcctaatct gacaggaaca
     5161 gaaaatctca aaatctttgc aaggcttaga ggaataccaa aaaaaaatgc agtagaatca
     5221 gcactggatg tagtcggttt gccaaacaat gacaaaaagt tattttctca atactctctt
     5281 ggtatgaaac agaggttggc gattgctctt gccattatgc atgacccaca actgttgatt
     5341 ttggacgagc ctatcaatgg gcttgatcct attggtattg cagaagtaag aacatttatt
     5401 cgtgatctct gcacagagcg aggtaaaact attttgattt ctagtcacat tctttctgaa
     5461 attgccttgt tggcagatga cattggcatt attgaccatg gtattttgtt ggaggaagaa
     5521 agtcttgccc aattagaaga aaaaaacagt aaatacatac attttgctgt atctgatgca
     5581 gcacaggcag caaggcttct ggaaacccaa cttaacctga aaaatttcaa agtagcagat
     5641 aattacaata ttatgctata tgatacagat gtttctgttg cagaaataaa tcgtgctttc
     5701 attctaaaca acattgaggt atcagaatct catttatgcg aagatactct tgaagattac
     5761 ttcaagaaag taacaggggg tgaaggaatt gcttgatata atttcatgtg aattttcaaa
     5821 actcaagcgg ttaaaattta tactgatttc tattttaggt gcttgcttat ttccaattcc
     5881 cgcaacaatt ttgattgcaa aggataactt gccctttgag caattgttca aattagttgt
     5941 caattttgga tattttttgc tattaccaat tgtattaagt attgttgcta gccaactatt
     6001 ttttatagaa agagataatg atgtattaaa aaatcttgca acagtgccag tgcaaaaagg
     6061 aaaactggct ctggcaaaat tggctgtgtt gctgtttata tcattgttct actctgttgc
     6121 agggttagga gctactatca ttggaggttt cattgttgga atagtagagg gggttgctgt
     6181 aaaattagga atgagcattg cttttggaat tatgtttttt gttactgtac ttcctgttgt
     6241 ggtactcatt gtatatttca atcgcagcta tattttttct attatacttt cttttgtata
     6301 tgctattttc aattttagta tatccttaaa tattatcaat tttgaaccaa ataacccaat
     6361 attaagtgta ttacctgctc ctgttataat gcgttggtgg atggcatttt ggggagatcc
     6421 cactggcgaa tacacggcac ttagacagcc atatttgctc tcaactcctg cttgtgtagg
     6481 tattttatgt ttgataacca ttatagcagt cctgctgatt tgtatgatat acaaaaagca
     6541 ggagaattag gaggtatcta tgcttgatat aattactaca gaatttcaaa aaataaaaag
     6601 atataatatt ctatggattg gtgttgttgc tgttctgttt tcagcactat tggcagtttt
     6661 tcaggttgta agttcacacg gcagtgaccc tctaacgtat gagagctttg caaacggagt
     6721 tatctggaat aatttcagtc ttagttttcc atttgggatt acacttattg gaggatatct
     6781 tattaaccgt gaatatacag accaaacctt aaaaaacatc ctaactgttc ctatttcatt
     6841 acgcaaattg ctagtgggaa aattaattgc ggttggagga attactgtat tgttaagtct
     6901 tttcagcttc ttatgcacat ttattttggg gttgttattt tgcaatatta atatatctgt
     6961 tacactcgtt gtaaaatcct tagttcagat tttgtctgtt aatctgtact gttatgttgc
     7021 tgttttgccg attattgctt attttggtcg taaacaaaat gcatttctga cgggtgtagg
     7081 gattgcattt gtatacggtt tttgtggtgt gtttgttgct ggaagaaatc tgacagactt
     7141 ttatccaatc acagcaggtc ttggtctagt tggatacaac aatggtgctg gtactgttta
     7201 tcagccactt attggtgcta tgactttgat tgtaattcta atcttgacaa ctattctact
     7261 tgtatttaca cctaattatg ataaagttat gaccatatct aagaaaaaag ggataaagca
     7321 taaaaagtat tctcataaat aacataaata ttgtttctat tatttaagtt gctagacagt
     7381 gaaaagaaaa aatctgtcgt acagtggcta tatgctcatg tattcaagaa gctacagttt
     7441 tgatttttca taactgtagc ttctttttgt atttattaaa tcacgactat cataatactt
     7501 gcaataggta tagcgacaag agagagtact gtcatatgtg ttttatatat tacattaagt
     7561 atattctaaa atatatgttt taaataatat atttgaaaat aggaatattt aaataaaaaa
     7621 aataatatta tatatagttg acaaaaattg gcaaatgata taatatataa atatagaaat
     7681 agtaatcatt actattatta aaagggagga attaattatg aacttaaaag gaactaaaac
     7741 agaaaagaat ttaatggcag gatttgcagg agagtcagaa gcaagaaata aatatacata
     7801 ctacgcttca aaagcaagaa aagaaggtta taatcaaata gctgctatat ttgaagaaac
     7861 tgctaacaat gaaaaggaac atgctaaatt atggtttaaa cttttacatg atggtatgcc
     7921 ttcaacagag gaaaatttaa aggatgcagc agcaggtgaa aactatgaat ggactgatat
     7981 gtatgcaaaa tttgctaaag aagctagaga agaaggattt gacaagatag cttatttatt
     8041 tgaagctgtt ggaaaaatag agaaagagca tgaagaaaga tacttaaagc ttttagaaaa
     8101 cttaaatgaa ggaaaaatat ttaaaagaga tgaagaagtt gtttggcaat gtcaaaactg
     8161 tggtcatgtg tatgtaggta ctgaagcacc agaaaaatgc ccagtatgtg accatccaaa
     8221 agcatatttt aatataaaag ctgaaaatta ttaaaaatta tcattattaa aaaggaatgt
     8281 taactatgaa attttctaaa caacgagaac tgattttaaa tgaaatatta aataatccgg
     8341 ttcatcctac tgcggattac ctatatgaaa acttaaaaaa agataatcca aatttaagct
     8401 taggaactgt gtatagaaat ttagctcagc taacggaaca tggctttata agaaaggtta
     8461 gtattccagg atatccagat agatttgatg gtcgaataga taatcactat catatcatat
     8521 gtgaagtatg tggagaggta tacgatttag aatccgaagt tcttaataat ttacaagaat
     8581 taatatctga ggagacagac ataaaaataa catcttataa cataagtttt aaagggattt
     8641 gtaataattg taaaaggtgt agccaagtag gttagttttc aaattctaaa aataattaat
     8701 gaggtgagtt tatgtgtagt gaacaaaaat tttttatatg tgagacttgt ggaaaccttg
     8761 taggaatgat acaaagtggt ggtgtaccta ttttctgttg tggaaaacct atgaaggaac
     8821 ttgttcctaa tacaacagat gcagcagttg aaaaacatgt acctgtaatt gaagtggatg
     8881 gaaataatgt tactgttaaa gtaagtagca caactcatcc aatgactaaa gaacatcata
     8941 tagcatgggt gtatcttatg actgaacaag gtggtcaacg caaatgtcta gcagtagatg
     9001 gagaacctgt agttaaattt gctttgaatg atgatgataa agtgatttct gcctatgctt
     9061 actgtaattt acatggatta tggaaggctg aactgtaata tttaaataaa ttgagtcaaa
     9121 aaggaggcta taaatgtatt ttcatacaaa tagcctccta taaatttata taaattcaag
     9181 ttttaatttt gtttaatgtc aatataatat aaggagaaaa taatatgtca atttataaat
     9241 gtagtgtttg tggatatatt tatgatgaat ctaagaatga taaaacatgg gatgaattaa
     9301 gtgaagattg ggaatgccct gtatgtacaa aaggtcgtag ttattttgga aagataagta
     9361 ctgtttacta tgaagaagat gaaaagatag cagaagacat agttgaagat gaatctaaat
     9421 taaatactga aaaagaggga gatttaaatt acttaagtac atatttaaga agagatgatg
     9481 aagttgagaa acatatggat ataattcacg aaatggctgt tacaggaaaa tctataatag
     9541 aacctatgag aactaaacta ccagtaattt cttgggatga tattttaatt atgggtgctc
     9601 aattaaatcc attaccttta aatgagcatg atgaagtaaa tacaacaaca ataataggaa
     9661 aaaaagcaaa gaaacctatg attatagaaa atccagttta tatttcccac atgtcatttg
     9721 gagctttgtc taaagaacta aaaatagctt tagcaaaggg tgcagcccaa aataagacag
     9781 ctatgtgtag tggtgaagga ggtatattac cagaagagaa ggaagcttca tacaagtata
     9841 tttttgagta tgtaccaaat aaatatagtg taactgaaga aaatcttaaa aattctgatg
     9901 ctatagagat aaaaattggt caaggaacaa aacctggtat gggaggtcat cttcctggcg
     9961 aaaaagtaac tgaagaaata gcaaaagtaa gaaataagcc tgtaggtcaa gatgtaataa
    10021 gtccatcttg ttttgaggaa atacaatcca aagaggattt aaagaaactt gtagatgaac
    10081 ttagagaagt ttcagaaggg cgtccaatag gtgttaaaat ttcagcaggt catattgaaa
    10141 aagatatgga atttatagct tatgctaaac ctgattttgt aactattgat ggtcgtggtg
    10201 gagctactgg agcaagtcca aagttgctta aagatgcaac ttcaattcca acaatatttg
    10261 ctctttatcg tgctagaaaa tacatagata cacatggatt agatatagat ttggttataa
    10321 caggtgggct tcgtatatct actgattttg ctaaggcaat tgctatgggg gctgatgcag
    10381 ttgctattgc aagttctgct cttatggcag cggcgtgtca acaatatcgt atatgtggtt
    10441 ctggtaagtg tcctgtagga gtagctactc aggatgagga attgagaaaa agattacata
    10501 tagaaaacag tgctaataga gtggcaaact ttttaaatgt aagtttagaa gaacttaaga
    10561 cttttgctag aacttctggt cataaagata tacatgattt aagtgttgat gatttatata
    10621 ctgttaactc tgaaatatca aattatacaa acatacagca tgtatagatt gaagtttgaa
    10681 actattagat tttagatagc tataaaagta aatgataaat atattttata aaagagagtg
    10741 tcttaaaatg aactttttag ttcataagtc actctttttt ttatgaagcc aaatatattt
    10801 atcattttag caatgaaaaa gaatcttatc tctttatttt gagatagatt ccttctattt
    10861 atgaaaatta aagatattaa attgtaaaat attctgtgat gtcgtactat taaactaaag
    10921 attctgtact ttaaagtaaa taaaaattta aggagtgatt attatggaaa gattgaagat
    10981 acaagtttta gtcgacaata atacttatat tgatagatac tttgttggag aaccagcagt
    11041 aagctattat attgagattg atggaaatag gattttgttt gactcagggt attcagatgt
    11101 attcatatca aacgctgaaa aattaaatat agatttagga aatttaactc atgttgtttt
    11161 ttctcatggg cataatgacc atacaagagg tatccagttt ttagaaaata ggtatgattt
    11221 atctacaatt gaacttattt cacatcctaa ctgttttata cctagaaaac atggagagaa
    11281 aagcatagga gctccatttt ctgctgagga aattaaaaat atttttatgt ataatcctaa
    11341 ggataagcca tttaatctaa gcaagaattg tgtgttttta ggtgaaatac cttctataaa
    11401 tgattttgaa aaaagagcta aaattggtaa atgtaaaata ggagatttgt gggaagatga
    11461 ttatgtttta gatgattctg ctatagtttg taaaactgat aaaggtattt ttattattac
    11521 aggatgttct catagtggaa tttgtaatat agtagagtat gctaaaaagg tatgtagaga
    11581 tgatagagtt attggtatac taggtggttt tcatcttttt gaattgaata ataggttaga
    11641 tagtacaata caatatttgg ataaagaaga aataagaatg ttgtaccctt gtcactgtgt
    11701 ttcttttaag gtaaaagcga agatgaatga aatattgaat ataaatgaag ttggagtagg
    11761 gctgaccata agtatatagt atttgaaagt atataagatt taagttgaag gttaaaaaga
    11821 tattttctat agaaaatatc ttttttgtta cgtttatttt aagagaaatc aatatacttt
    11881 tatatgaaat attgtaaaaa aatttatttt taatgagaat atattttcat taataaacaa
    11941 ttttattatg tattaataat gttacaataa atataaataa atcaaagtta cttacattac
    12001 agtatatttt ttcacaaaat atattgattt attcttttaa agtttgataa ttccaatgaa
    12061 tgtaataaaa gaagggattt tatactatat gattattatt ataaaataat aaagaaaaaa
    12121 ttatataata ataaagaaaa aatgtataat atttaacatt aaaaaagata tttcataaaa
    12181 ttaaaaaaca aagtgaattt gaatactatt taaaaaataa aataaatata taaaaaatat
    12241 ttaatataaa ggtagaaata agttgaaaat gtaaagtcat tggaaaaata tagttgaatt
    12301 taatgagcaa aaatgttatt gttttatcaa taaagtgtta aaataaaaac ttttaatatc
    12361 attttaggga ggatgatttc atgcaaaaaa gtgtaaagaa agcaaaagta acgggctcta
    12421 tgttagccat ttttggtgtt gcaagcgttc tttttagttc acatgcagga ggaggatttg
    12481 ctacagggaa tcaagaaact cagtactatg tgcagtatgg atggacagca ccacttatgg
    12541 caattttagc aatgattata cttactgcta ccatgagaga agttatcata atgtataata
    12601 ataataattg taggaattat aaggatttat tttgtgagct ttggagacca tatccaaaac
    12661 ttgaaataat atgggagata tattactatc taatggtttt aatagctgta agtgctgtta
    12721 tagcaggtgc agcagcagta tttcaaagta taggagtaaa ttattttgta gctgtattta
    12781 ttattggagt tgtacttctt gtctttacta tatttggtgc tatgcttgta tctaaagcag
    12841 ctacagcaat gacaatagct attctagtat gtactcttac tatttttatt gttggtataa
    12901 aagctaaagt accagaaata actgaaatat tatcaaatag aacgagtttc acacctggct
    12961 atatcaagcc aatacttaat acttttattt atgcaggttt tcaatcggtt gttataccta
    13021 cacttgcagg atgttcaaga ccacttctta agaactcaaa agaagctact aaggcaatga
    13081 taatttcatt tgttatgaat gcaattgcat taggacttgc tgtaactatg ctaatgggat
    13141 ggtatagaga aattattgct gctgggcaaa caacactccc tactctttat gttgcaggtc
    13201 aatctggaaa tcatactata tacataattt ataatgttgc attattcctt tgtttaatgt
    13261 ctacaggagt aactactata tttggtcttg taaatagatt tgaagaccat aaagcacttt
    13321 ctttcctttc ttcaagaatg aaaagaaggg tatttacagc ttgtgcaata atggtagtgt
    13381 caatgcttat atcacttaca ggattaagta atattgttaa atatggatat ggatattgtg
    13441 gttatcttgg tctattcact atagtaattc cattccttac actaggacat tataagaata
    13501 agaagtttgc aaaggaaaat ccagaagcta aatggccagc ggaattaaat gaaaatgtaa
    13561 attagatgta gtagcaaaaa atattgctaa agagaatact atagataaga atactataga
    13621 taatatatct gcatgtttat taagattatt tgcaaaatct aatattaaac aactataaac
    13681 aagcaatata aaactaagaa taaaagataa aaagagggtg tctcaaaatg gacttttagt
    13741 ttataaggca ctctttttta tatgaagtca agtatatttt cattattttg acaataaaag
    13801 agactaatcc tactttggat agcctctttt ttctttaata taaaatagta taacagcaaa
    13861 gtatagattg atacatgttt tctgtagctt tctatatatt acagtgtttg tgtggcattg
    13921 gtattttaag caatctataa attataattc tataattctt ctactaattt tagattctat
    13981 agccgtctct atttcactta acattcgttc atttttaggg tcaataaaag cacatgtata
    14041 tccttcttca ccagctctac cagttctgcc aatacggtgg atgtagtctt ctggtgtttc
    14101 tggtaaatcg taattatata tatgacttac tccagatata tcaagaccac gagaagctac
    14161 atctgtagct attaagtatt gtatatctaa acttctaaat gatttcatta ttctttctcg
    14221 ttttgattga gcaatatcac tatgaagttt ttgacaatta tatcctctta tagcaagagc
    14281 ttcttcaaga tggtcaaccc ttctcttagt tctacaaaat attattgcca taaaaggatt
    14341 atcttcatct agtaccttac ataaggcatc taattttttt ctatctgtag tttctactac
    14401 ttcttgtttt atattattaa gagtgatttc ttctttttga atagaaacta caacaggatt
    14461 ttttgtgtat ctataagcta atttttttac ttgagaattt atagttgcag aaaagcatag
    14521 tgtttgcttt ttgtttgaag tctcttttaa aatagcttcc acttcatttt taaatcccat
    14581 aagcaacatt tggtctgctt catctaaaac aaaagtcttc aacttactaa ggtctattgt
    14641 ttttctattt agatggtcta aaagcctacc tggtgtagct ataatcatat gaatatttcc
    14701 ttttagtttc tttatttgag aaccaatatc ttttcctcca tatgctgcaa gaatacttac
    14761 atctttagat tctttaagtt tcatagcttc ttctgttatt tgaatagcta gttctcttgt
    14821 aggagaaagt ataagtactt gtatatcatt tatatctaat gatatatttt caaatatcgg
    14881 aagtaaaaaa gctagtgttt ttcctgttcc agtttgagct tctgctatta catcttttcc
    14941 ttcttttatt agtttaatac tttctttttg tataggtgta ggtgttgtta ttcctaattt
    15001 ttttagaata tttattgtat tttcactaat ccctaagctt ttgaaatcca ttgttatctt
    15061 acctttcatg aaaaattttc ttttttatta accaattaat aatatcatat ttgtaagtat
    15121 ttttagtaaa ttttttaatt attatttata tagcttaaaa atatattaag atactttaaa
    15181 atggaatgta acttaaatta aattttagta ggaattttat aggtttattt ttaaaggttt
    15241 tttgaaaata aatctattta aaaattaaat taaaatgcaa gaaaaacata ataactttca
    15301 tttttaagaa gttttcacaa aaaagaaaaa atatagtgca ataaatgata caaagtaata
    15361 taatagatta caagatatga aaagctaaaa aaataaattg caaatgaaat taaaatgaat
    15421 aaaaaataaa aaaataatca taagttagag gtatcaatga aaaataagac ttaatgtttt
    15481 taaaattaaa agtatactaa ggggggcatt aatatgtgcg ttatatcaaa agatagagca
    15541 aaggaaataa aaatagtaga tactacttta agagatggag agcaaacagc tggggttgta
    15601 tttgcaaata gagaaaaaat aatgattgct gaaatgttaa gtgacctagg tgttgaccaa
    15661 attgaagttg gtatacctac tatgggtgga gatgaaaaaa atgtaataaa gcacatatgt
    15721 agtagaaatt taaaatcaga tataatggct tggaatagag cagtaataaa agatgttgaa
    15781 gaatctattt cttgtggtgt tgatgcagta gctatatcaa tatcagtatc tgacattcat
    15841 atagaaaata aattgagaac ttctagaggc tgggttttag aaaatatggc taaaacagtt
    15901 gaatttgcaa agaaaaatgg attatatgtt tcagtaaatg gagaagatgc ttcaagagca
    15961 gatatagact tcttaactga atttataaat gttggaaaac aagcaggggc agatagattt
    16021 agatactgtg atacagtagg agttatgaat cctttttcta taaagaatgc aatagaaact
    16081 ctttatgaaa gaactaattt tgatatagaa atgcatacac ataatgactt tgggatggca
    16141 actgcaaatg cacttgcagg aatagcagca ggagcaaatt atgttggtgt tacagtaaat
    16201 ggattaggtg aaagagcagg aaatgcagca ttagaagaag ttttaatggc acttaagtgt
    16261 gtttataaat gtgatttaaa taatatagat actagaaaat ttagaggaat atgtgagtat
    16321 gtagcacagg catcaggaag aatacttcct acatggaaac cagtagttgg ggataatatg
    16381 tttatacatg aatctggtat acatgcagat ggagctttaa aagacccaca taactatgaa
    16441 ccatttgacc caagtgaagt aaatcttgaa agaaaaatag taataggtaa acattcggga
    16501 agagctgcag ttgtaaataa gttgagtgaa tatgaaatgt atatttctcc agaaaacgct
    16561 accaagctat taaatgctat aagagctaca tctataagat taaaaagaag tttaatggat
    16621 aaagaaattc ttcaattata ttgtgatata ctagcacatg agaaaggcac aacagaagaa
    16681 gaagcagtta gaggttcata tatttaagat ataattgttt aggaggaaaa tatgggagat
    16741 aatatagttt ataaaataat taaaaaacat atagtagatg gagaagctgt tgctggaagt
    16801 tcaattggta taaaaataga ccaaacttta acacaagatt ctactggaac aatgacatat
    16861 cttcaactag aagctatggg aatagataaa gtaaagacta aaagaagtgt ggcatttgta
    16921 gaccataata tgttacaaca aggatttgaa aatgcagacg accataagta tatacaaaca
    16981 gtggcagata aatatggagt ttatttctct aagccaggaa atggtatttg tcatcaagta
    17041 tttttagaaa gattttcaac accaggagat acacttttag gttctgatag ccacacacct
    17101 actgctggag gtgtgggcat gatggctatt ggagctggtg gattagatgt tgctttagcc
    17161 atggcaggag gagcatacta tataaaagca ccaaaagtct gtaaggtgaa tctagttgga
    17221 aaattaaata atatggtatc atcaaaagat ataatattag aagtgttaag aaaacaaact
    17281 gtaaaaggtg gagtaggtaa agtttatgaa tatggtggag aaggtgtcaa aagcctatct
    17341 gttccacaaa gagctacaat aacaaatatg ggggctgaac ttggagcaac tacttcaatc
    17401 ttcccaagtg atgaaaaaac actagaattt tttaagagtc aaggaagaga agacgcatgg
    17461 gtagagctaa aaccagatgc agatgcagtt tatgatgaag agattactat aaacttggat
    17521 gaattaaaac cattagctgc aaaacctcat agcccagaca atgtagatga agttgaaaat
    17581 ataggcaaga ttaaaataga ccaagtggca ataggaagtt gtacaaattc ttcttatgaa
    17641 gacttaatga aagtagcaca aatcctgaaa ggaaataaag tacataagga tgtgagtttg
    17701 gtaatagcac caggttcaag acaagttatg gagatgattg ctagaaatgg ggctttggca
    17761 gatataataa gtgctggagc tagaatacta gaaaattctt gtggtccatg tattggtatg
    17821 ggtcaatctc caggtactga ctctgtgtct ttaagaactt tcaatagaaa tttctatggt
    17881 agaagtggga ctttgtcagc acaagtatat ttagtaagtc cagaagtggc agcagtaagt
    17941 gcaatcaagg gagtgcttac agacccaaga gaatttgata ttaaatttac aaatttagat
    18001 gtaaatgaat ttttgataga tgatagcatg ataattaaac ctgctgatgt aggaagtgat
    18061 gtagaagtag ttagaggacc taatataaaa cctttccctc ttaatacaga gctaagtcag
    18121 tctataggtg gaaaagttat attaaagaca gaagataata taactactga ccatataatg
    18181 ccatcaaatg ctaagttact tccttttaga agtaatatac cgtatcttgc aaactattgt
    18241 ttcaatactg tagatacaga atttcctcag agagcaaaag acaataatgg tggatttata
    18301 gttggtggag ataattatgg tcaaggttca agtagagaac atgcagcttt agcaccatta
    18361 tatctaggtg ttaaaggggt aatagttaag agctttgcaa gaatccacaa ggctaacttg
    18421 ataaatagtg gtataattcc aatggagttt tgtgatgaga aagattatga aaatatatct
    18481 cttttagata atctggagat accaaatatt ttagacaatc taggtagtgg aattttagaa
    18541 gttaagaata caactaaagg aacttctttt aaggtcaaag tagaattgtc agcaaaagaa
    18601 gttgatgtat taaaagctgg tggaaaatta aactacacta aaaatcaagc taattaatat
    18661 gaaaagaggg aatattgaat gtataaagtg acacttatac caggagatgg aataggacca
    18721 gaagttgcga aagctatgaa aaaggtagta gaagctactg gagtagaaat agaatgggaa
    18781 gaagttaatg caggagaggc agttattgaa gagtatggta ctccacttcc tgaatatatt
    18841 atagatagta taaaaaagaa caaaatagct ataaaaggcc caattactac tcctgtaggt
    18901 aaaggattta ggagtgtaaa tgtaacttta agacaagcat tagatttgta tgtcaattta
    18961 agacctatta aaagttttaa ggggataaaa tcaagatatg aagatgttga tttagtggtt
    19021 gtaagagaaa atacagaaga tttatatgct ggaatagaac ataaaatagg tgattatgca
    19081 gctgaaagta taaagataat aacaagaagt gcaagtgaaa gaatcgttga ttttgcatgt
    19141 aactatgtta aagataataa gagaaaaaaa gttacagcta tacataaggc aaatataatg
    19201 aaaatgtctg atggattgtt tttagatgtg tttagagaag ttgcatcaaa acatggtgta
    19261 gaatatgatg atttgattgt agatgcagca gctatgaact tagttttaaa tccagaaaat
    19321 tatgatgtaa tggtaatgcc aaatctttat ggagatatac tatcagattt aggtgctggg
    19381 cttgttggag gtttaggtat aattccaagt gcaaatattg gtaaagattg tgcgatattt
    19441 gaagctgttc atggaagtgc tccacaaata gcaggtcaaa ataaggctaa tccaacagca
    19501 cttattcaat catcagtaat gatgcttaga tacttaggtg aatatgaaaa tgcacaaaaa
    19561 atagaaacag ctttagaaaa agtatttctt gaaggaagta aattgactgt agatttaggt
    19621 ggctcagctt ctactacaga gtttgcggat gaggtgtgta agtatattgt atagatttta
    19681 tttagggaaa aagtaaaata tagattgaag aaaagaggct ttctcaaaat agagataagc
    19741 cttttttatt ggaatgataa aatatatttg attttataca aaagagagtt cctcataaac
    19801 gaaaaagtta attttgggat atccatttta attttaaaat taattgatta atatgcaaag
    19861 aaagattaaa taaatttatt atttttaatt gaactttcaa ccaaaatatg gtaaaattta
    19921 aaaaagttga actttcaact aaaaatgaat atattgatta tgtgaaattc tataaaacag
    19981 aaactatttg actttagcca tagtagtttc agtggaggtg tgtttgatta agactttaga
    20041 cagtaatata ttaagagaag taggtacttt atctagagca gtaaattcaa taaatgatat
    20101 taagtacaag gaattaaagt tacaaaaagg acaatttaca tttttgacaa gaatctgtga
    20161 aaatcctggt ataaatcttg tggaattatc aaatatgtta aaggtagaca aggctacaac
    20221 aaccaaggct atacaaaaat taataaaggc aggatatgta gataaaaagc aggatgagtt
    20281 tgataaaaga ggatataatt taactccaac tgataaatct ttggaagttt atgagttgat
    20341 aattgaagaa gagaatagaa gtatagagat atgttttgat aattttacag atgaagaaaa
    20401 acaagtggta actaagttat tagaaaaaat gagcaaaaac gtagaaaatg aatggtttaa
    20461 agtaaagaga tagtaaataa atacattaac ttaaggagat atttttatga ttagaaaagc
    20521 gaatatgaat gatttagaaa gcattatgaa aattataaaa tctacagtgg aagaaatgaa
    20581 gacttataat aatacacaat gggatgaaaa ctatccatta gaaaaagact ttgtttcaga
    20641 tattaagaaa caagatttat atatttatga agtggatgga gaagtagcag ggtttatatg
    20701 tcttaattat gaagagccag aagaatattt aggcttaaat tggtcatcta ataaaaaagc
    20761 aatggtaata catagaatgg ctgtaaatcc aaactttaga aagacaggga tagcatctaa
    20821 gttagttgat tttgctgaaa aattagctgt agaaaacaat gtatcatact taaagagcga
    20881 tacatattca ataaactcaa aaatgaattt attacttaca aagtgtggtt ttataaaaat
    20941 cggagaaatg agttttttag gaaaggagaa atctttctac tgttatgata aaatattata
    21001 aagagcattt acaatacaag gggtaaataa tagattttca gcattagtaa gggcataata
    21061 taacttagta tatgctatta tgaaagggat gatttatatg attggatttc taaagaaaag
    21121 aagaagtatt agaaaataca aggatgttga agtagaaaaa gaaaaattag ataaaatatt
    21181 aaaagctgct cttttagctc catcatcaaa ggggcttaga acatgggaat ttatagtggt
    21241 agatgataaa gaaaagctaa ttaatttatc tcaatgtaga actaaaggtg gtggattttt
    21301 cttaaaaaat gcacctttag ctattgtaat tattgcagat aaagaaaaaa atgatgtttg
    21361 gatagaggat gcaagtatag ctgcttcata catacaactt caagctcatg aactaggttt
    21421 aggttcttgt tggatacaag taagaaatag aatgcatgat gataatatag aagctgataa
    21481 gtacattaga gaagaattaa aagtacctag caagtacagt gtagaatgta taatttctat
    21541 aggatatcct gatgaagaaa agaaagcata cagtgactct gatttagact ataaaaaggt
    21601 tcattttaac aacttttagt atataatatg ttgtattaag acattatatt tttttctatt
    21661 gttaatatat acttaaaatt gtaaaaatat atctgaattt tactaactta tctaggggtt
    21721 atgtacaagg attttaaaga taaatataga aattaatgtt tataatcgat acataacttg
    21781 agtaacaaaa tttaaggagg ttaaagtatg ggtatattta aaacaaaaat ggatgaggac
    21841 tggaaagtaa actacattaa agagtttaat gaaatgagag attcttatga gagtaaactt
    21901 caaaaaaaac agtttgaggt agatagtttg aaatcagaat tggatagact aagaagctat
    21961 aaaaatagcc ttaagccaaa agaaaaacaa attactgatg atgatataaa taatataaag
    22021 agtttaagaa gagatggctt aagctataaa gaaatttcaa atcaaacaag ttggagcaaa
    22081 gcaactgtaa gtagggtatt aaatggactt tacgattagc atatacatgg ggtgatttaa
    22141 attgggatga agtatagtta caaaaaatgc ataatagatt ctattttatt gatgtttata
    22201 gttcaaatat taaggatgat tttgaattat gtacttctaa gtcaatttga atttactctt
    22261 gaaaatttta atattataaa cttaatttct tttacattag ttggtttatc gttaatttta
    22321 tttttaaaag ataattcttt gtataacaag gttagaaata gaaaaatcac agaagctttt
    22381 gaagaaaata aaaacaatat acttattgaa aagtgtaagc tgatactttt tgttgtggtt
    22441 ttatctttag caataattgt aacttattgt actaagggat atgtactttt taatgtaact
    22501 atgatgactt tgtctgtatt gatagttcca atatttgaag agttattttt tagagaatat
    22561 atatggaact atctaagtaa ttttataaag tcaaagagta aaattatctg tataacatct
    22621 atactatctg gaatttataa tataggatac atagatgtta taagaaatta tgtaatattg
    22681 tataacaatt cgagctacac ctttgaagtt attatttcaa aaattatgat aggtactgtt
    22741 tttggtattg tacttggatt agttaagtat aggtttagag atgtagggtt ttgtatatta
    22801 ttgaggagct tatttgctat atttattagg tagatagtat aatcggttta taaggttgtt
    22861 ttaaatttaa ttttaaatca accttatttt atttgtgttt tataaagcac ttatatatta
    22921 ataactaata aatttaataa aaattatttg aatattttta aaatatataa atatgtattg
    22981 acatataaat attatgaatt acaatttata taaactaata aaaattaaat aatattaatc
    23041 aacttattga atggaggaat aaaaatgaaa tttgtgactt tttgtagtag caatgaagaa
    23101 aaaataggtg tatttaattc agaaacaaat agtatatatg aaattaatag tttaggatta
    23161 agtaaattat atactgatat gaataatttt attgaaaacg tatctacagg agatttagaa
    23221 aaaataaaaa acaattcatt tgaaaacgca aagtgttata agttagaaga agttaaatta
    23281 tgttccccaa ttgtaagacc taaaaaagat attatatgtt taggtctaaa ctataaagac
    23341 catgtcaatg aaatcccaga tggagttata aaaaacgtag ttatgccaga ttatccaatt
    23401 tatttttcta agagagcaga caaaataatt ggagtggatg ataagataag cttacatgga
    23461 gatttggtag agaagttgga ctatgaatca gaacttgcag taatcatagg taaagaaggt
    23521 ataaatatat caaaagaaga tgcttatgaa tatatatttg gatatacaat agtaaatgat
    23581 ataagtgaaa gagcacttca agataaacat gttcaatggt ttagaggaaa aagcttagac
    23641 acacatacat ctatgggacc ttatatagta cataaagaag aatttgaaca tcctttaaaa
    23701 ttagatataa gtagtgtagt aaatggagaa gtaagacaaa attctaatac agagtacttt
    23761 atatttgata tacctactat aataaatgat ttatcaagag gaatgactct aaagccagga
    23821 gatataattt caactggaac tccagcaggg gttgctatgg ggatgaatcc tcaagtatat
    23881 ttaaagcatg gcgatatagt tgaatgtaaa gtcgaaggaa taggagtttt aaaaaatata
    23941 gttgattaat ggataaatat gccatataat tttattagta cgaataattt aattaatata
    24001 ggattaatca aacttatgat taatttatta tagagaggga tgagtatatg gcaagagaac
    24061 tagaattaaa gtatggctgt aatccaaatc aaaaaccatc aaagatttat atgaagaatg
    24121 gagaacttcc tatagaagta ttaaatggaa aacctggata tataaatttt ttagatgcat
    24181 ttaatagttg gcaacttgtg aaggaattaa aagaagctac aggtctccca gcagcaactt
    24241 catttaaaca tgtaagtcca gcaggagcag cagtaggggt acctttatca gatactttaa
    24301 agcaaatata ttttgttgat gatttagagc tttctccatt agcttgtgct tatgcaatgg
    24361 caagaggagc agatagaatg tcttcttatg gcgattttat agcactttca gatgtatgtg
    24421 ataaggagac tgcaactatt atagcaagag aggtttctga tggtataata gctccaggat
    24481 atacagatga agcccttgaa atattaaaag gaaagcgtaa aggcaactat aatattgtaa
    24541 aaatagatga aaattatact cctgaaccta ttgaaacaaa ggatgtttat ggaattactt
    24601 ttgaacaagg tagaaatgaa atattaataa atgaagacct attaaaagat attccaactg
    24661 ataataaaat ttttacagat agtgcaaaac gtgatttaat tatagctctt attacattaa
    24721 aatatacaca atcaaattct gtttgttatg ctaaagatgg acaagtaata ggggtaggtg
    24781 caggtcaaca atcacgtatt cattgtacta gacttgcagg taacaaagct gatacttggt
    24841 atcttcgtca acatcctaaa gtattaaact taaaatttaa aaaggatata ggtcgtccag
    24901 atagagataa cactattgat gtatatcttt ctgatgatta tatggatgtg cttgctgatg
    24961 gcatatggca aaactttttt gaagaaaaac cagagcctct aactggagaa ggaaaaagag
    25021 catggcttaa aactttaaca ggagtagcac ttggttcaga tgcatttttc ccatttggag
    25081 ataatataga acgtgcaaaa agaagtgggg taagttttat agcacaacca ggtggttcta
    25141 ttcgtgatga taatgttata ttaacttgta ataagtataa catagtcatg gcatttacta
    25201 aaaatagatt attccatcat taaaatactg aaagtataaa gataatatag attaggtaaa
    25261 aatctacaac aagttttgtt gtagattttt ttatttgctg tataatttta aatagaactt
    25321 tatttttaga tattcaattt ggaggttgat atggctttaa atataagaaa ctatagccta
    25381 ttatgtaatc aaggaacagc taaatttaat gaagatgtag tcggtataaa tccatttggg
    25441 gcatgggttt tagatggtgc tacaggactt aatggaaaaa atttagtgtc aactgaaagt
    25501 gacgcaaggt ggtatgttca gtggtggaat aggtatttat ataaaaatat aaataaagaa
    25561 gaatcattaa agagtattat taatactgga ataatagaag taaaaaaaga gtatgaacta
    25621 agattaaatg ggtttaaggt tgaaaaatta gatttaccat ctagttctat agttgttgta
    25681 aaatttcatg aaaataaagt agagtatttt ttattaggag attgtgcttt gtttattaaa
    25741 aatggagatt ccaaagttat aaaagatagg agtatttgta aatttgataa tactgtattt
    25801 gatgaaatga gtaaactttc taacttggaa gagatggctt ttgatgagat tagaactagt
    25861 gttatggata caatagtaag caatagattg aagaaaaata caaaagaggg ctattggata
    25921 ttggattttg atgaggaagc tgtggaaaat tctatatatg gatacattga aataaaaaaa
    25981 gattttcaat tgatgctaac gagtgatggt tttacaagtg catgtgatag atataatcta
    26041 ataaaagaag aagaattgat acgtatagca gaaaaatttg gtataggata tatacataat
    26101 aaagtaaggg attttgaaga taatgactat aaagcggtta aagtgccaag atttaaagta
    26161 aaagatgatt catcttgttt atatttagat atatataatg attagactgt ataaaactat
    26221 ttaattttag aaaggaggca agtgaaaagt gaaaattctt catataataa cacaaaaacc
    26281 aaatagtaca ggtagtggta tatatttgtc tggtatgata aaagggttcg aaaaaatcgg
    26341 tcataagcaa gctgtaattg caggtataga tgtaaatgat gatgtaaatt gttttccaag
    26401 tgaagtaagt ttttatccag taaagtataa ttgtggggag ttaaattttc ctgttgtagg
    26461 tatgagtgat tctatgccat atgaaagtac aagatataaa gatttaaata tagacatgat
    26521 aaatagattg aaatatcaat ttaaagtaaa tatagataag gctatgaatg attttaaacc
    26581 agaacttata atatgtcatc atttgtacct cttaactgca tttgttaggg aaatggtaaa
    26641 agatataaag gttatgtcta tttgtcatgg aacttgttta agacagttaa ataccattga
    26701 tttagagaaa gaatacataa tagcaaatat aaggaaatta gatttaatat ttgctcttca
    26761 tgaaaatcag aaatatgata ttataaagac ttttggagta agtgaaagta aagtagttgt
    26821 aattggtagt ggttataatg atgatatatt ttataataaa aattataaaa taaaggatga
    26881 taaaataaaa atagtatttg caggtaagat atgtaaatca aagggactga ttccatttat
    26941 aaaagctata tctaaattaa aatatagtaa agatttaata gaagtcaatt ttgcaggtac
    27001 tggaagcgat atcgaatcat ataatgagat agttaaactg gcaagtaagt ctccatttaa
    27061 aatgaatttc ctaggaaagt tagaacagag agatttagct gagctattca acaggtcaca
    27121 aatatttgtg ttaccatcat tttatgaggg attaccagtt gtagttttag aagctttatc
    27181 ttgtggcaca gatgtaatca ctactgatat tcttggtgtt aaagagtgga ttggtagtga
    27241 gattaataat tctggaaaga tagaatatat ttctctacct tttatggaga aagaaggtat
    27301 tccaaaagat gaagagttat atgattttga aaataatttg tataatgcaa tagattctaa
    27361 gatacaatct ttattgaata actcaaataa gaaaacatct gtagatatgt caaaaaaaac
    27421 gtgggatggc ttagcatata gaataaatga agttatttta atggatgaat tgtgtttagt
    27481 ctaaaattat ttaaattata aaaaagtgta actattttta cactattttt aaatgatttt
    27541 atattatact aatactaaat atatttgttt tagggaggta atttatgagg attagtaaaa
    27601 aggtattggc gttaggtatt tcagcattac tgttaagtgt tagttttcca acatcaataa
    27661 acgcactaga taagattgaa aatattcaag gagtagataa atatgaaaca gctgggctta
    27721 tttcagataa gcaagatttt acaacagcag ttcttatcaa tgcagattct acaatggtag
    27781 atggaattgc tgcaagtggt cttgcaggag taaataatgc agctatttta ttaactaata
    27841 aggatgatat accagaagca acgcttcaaa gactgaatag agttactaag atatatgtaa
    27901 taggtggaga aaattctata agtaaagatg tagaaaaaat gttacttatg agaagaatgc
    27961 aagttataag aattgatggt gtagatagag tagatacaag ttataaaatt gcaggcgaaa
    28021 tagaaaaaat taaaaacagt gataagatgt ttttagtaaa tggatttaag gatgaagctg
    28081 atgcagtaag tgttgcatct gttgcttata gagatggagc tcctataata ttgacaaaag
    28141 atataccttc agcagaagaa gacacagact tagacccatg gtttggagtt tctcctgttc
    28201 cagtatatgc tattggagga gagtctacat taagtgatta catagtgagc agatatagag
    28261 caactagaat tggcggtgtt gatagatatc aaactaataa aaatgttatt gaaaagttct
    28321 ataatggagc aaaagagttc tatataacaa gtggagacga tttagtttat gctttagttg
    28381 catcaccact tgcaaaaaat gctcctgttg ttttagtttc aaataaaagt gataagagta
    28441 tattaagtgg agctagtaaa gtaacagcaa taggtataag tgataagagt attatagagc
    28501 aatgtttgga tgctgtaaag aagtaatgga gtgttattag taaaatgaat atacacattg
    28561 aaaattagta gattgttcat tttataatgg tataaaatat atgggaagag gctatcaaat
    28621 ggagataagc ctctttttca tttatttttt tgcgtccctt attggtaata aaagcttccc
    28681 ctgctaaaat tcttccccaa aatacggttt cttcttggtt ggtttttttt acagccattt
    28741 cagatatttt tatcaattca cagtttgctt caaaaaatac ggttttcaac catgagtgaa
    28801 attctgtcag agtatcttgt gtaacatcat gatgacaaac ttccgtagat attaccatat
    28861 taaatatttt caattttggg ttcattccac ctgctgtccc tgaattgaga acgatattta
    28921 cttcaaaaag gtcaatactt tagtttccaa aaaacgggga tttattgctt tcgtttactt
    28981 tttcgatttt tccagacatt gtataaaata tctttaagaa ttaacattgc ttccagttca
    29041 ttatattggt attcctgttt taattcgtcc aacatcatgt taaccttata agcataatta
    29101 gaaatattaa catctgtctg atatttaaga agaatagggt atttttttcc ccaggcattt
    29161 gtccaattga ttttttcttc ggtttcctca cttgttttat taatcgcttc ctgaatttct
    29221 tccatgtcaa tatcaaaatc aatcaattca tctaatgaca cattgtaaag tattgctaat
    29281 ttttttgact gacgaatgtc tgggactgtt tcatccgttt cccattttga aacagtctgc
    29341 ctgcttaccc ccagtttttc agctacatct tcctgtgaaa gcccatgttt cttccttgcc
    29401 tgaaataaac tatttcctaa attcattgaa attcctcctt atctgtttat gggattatta
    29461 tattatttga taagaacaaa ctctaccaac taaaattatc atatttgcta tttttattaa
    29521 cataattcaa agacgtattt attctgcaaa ttaaaatctg ctaacctctg cgaatatcaa
    29581 tcattaacca cttttatcca ttccctgttt ttgtttgtac gtaaatatct cttaattctg
    29641 gtgtaaactc ctgtaaaatc gcttcgacaa cctctttctc tttctttcaa acaacaacta
    29701 aaacgtaaaa taattttctt tcggatatac tgtgcataaa ttttttctag gttttttaaa
    29761 tttgatattc cagccaaatt cccaactgca agaactaaat atctattttg agacactatc
    29821 tccttttctt atattatatt attttttata tggaataaat ttcataagta ttatcttcct
    29881 ttaatttttc taaccaaacc atttctaaaa tatctagttc ttctaaatag tctttctctg
    29941 ttttgttatc atcatgtttt ataagctcta aaacttcaaa tgtaaatgct ttttcaccat
    30001 attttttcca ttcattattt aattctttta tcatacatga gccagcacca agctgaaatt
    30061 tgagagagtt aaatttgctt tttatatcat tactttttcc aaggtaaatc tttttagtaa
    30121 tatcattttt tattatgaat acacctgtgt caaatttcat ttctttgtat aattgtttta
    30181 attcacgttt tctatccatg attttagata cctctcttta taattgatat gtaatatgta
    30241 agtgtaaaaa tatattacat atcaattata aagagattaa ttttatatgt aaatagtttt
    30301 tataaattta attatgaatt agtcatcaat aaacaagaaa tttagctgta gaaatccatt
    30361 ataaaggcta ttataaattt taatatgcta aaaatataaa aagaatagtt gacagtgtag
    30421 aaaatatgga ataaactaaa agtgtaatag taatattaaa ttatatatta cattgaaagg
    30481 tgtgaatgat tattatgaat aaaaaaatag aattaatagg gaattttgca agtgattgga
    30541 ttaggtatag tgattatgaa tataaaatta ctgaagaaga tgaattatat atagttccaa
    30601 cagaagatgc tgtgtttacc atgtataacc catttgatgt agcagatgat ataatagtag
    30661 atataattcg cataggacaa gaggcattac aagatatatc aaaagagaca aaagaaatga
    30721 aactaaagaa agaaatactt gaatttgtaa aaaagtatgg attattgggt ttaatatatt
    30781 caagtgtata taatagagat atagttggag aagaaagagt actgatgatt gaaaagaatt
    30841 atattacaaa agagaatata ttgagtacag atgaatatgt aaacatgttt ataccatttg
    30901 caagtgatga agatgtgtat tttaaaaagt atagaagggg tatagatgta tcaaagagag
    30961 aagaatctcc aaagtttttt ggaaagagac cattgatttt agatttagta ttttcaaagt
    31021 tctacactga acaactagat tggattgtaa gttttgctaa agatatgtgt aagcatttta
    31081 atcaaatttg tgtatataaa aatacatcta atctattaac tgaaagtgtt actattatgt
    31141 ctggagggtt taatcctcaa aagataggat tttctataag ccaattagat aaaccaatta
    31201 ttgcatggga gtttgattct ttgaaaacag ctattgagac tatctatgcc tttgcaatta
    31261 caagtgaacc ttcttcttta aataaatgca agtactgtgg taaaatttat attcctacaa
    31321 attctaaatc tcaatactgt tcaccttctt gtagaaattg ctcaaatgta aagaaaagta
    31381 gaagtagagc caaaaaagat aaataaaatt aataaatata tcattgttta gattttagta
    31441 aataactact gaattaaaag ttgttatata aaattatata tctaaatgat ggtatttttt
    31501 ttgttgagaa aattgaaaag tttaattgag atagtaattt tgagttgaca aaaaccactt
    31561 ttaacactac tattataagt ggttggtaaa ataatatata ctaattcaaa tatagcataa
    31621 aaaacaaaaa aagtcaatgg aaaaaataaa aaaggagaat ttaaaaatga tatcacctat
    31681 tattttgagt tctataaatc agaatttaaa ggaaatagaa agaaatgaac tgcttgaaac
    31741 taatatagaa tctggagatt atggtctagc tctttctgaa tctgatgtaa aagatataat
    31801 aaattcgaga gataatactt taaaggggta tggaagaata gaattagata taaaagttac
    31861 aaaacagtta atagaaaata tatatacatc acaatataca aatgtggaca attatttaga
    31921 ggctattaat gatatgcaag aaatttttta ttatttaaaa aatgaaactg atgacaagat
    31981 atgtgatgat gagattatag aaatactggg tgatttttat gaaaaatttt caggcaatat
    32041 ggacaatgta agaggagaag cagacgaatt tgcaaagaaa tttaaatttg gagaagttta
    32101 atatatgata ggagagattt tgtatgttaa ataatttaag taatattaat ataaacgaaa
    32161 ataatttaat aaagaaccaa tattccatat ctctacttaa ggaatgtcta aattgtaaag
    32221 tgatagatga aagagaagta tataatatac aacaagaaat atctctaata cttatggatt
    32281 tgattaaaaa atatacaaat ggtcaaagca catcagtaaa aacagaagtt gccgaaaaac
    32341 tgttgatttc aatatggtat gctattgatg catatataaa taagcttgga gatatagaaa
    32401 aaagagttgt ggagttgact gctaagaatg ttaaaaaagt gtaccttgga ggaattgaaa
    32461 tattagagga agagttagtt aggctaaaag atttttataa actaatgatg agtagaaaat
    32521 tggatactaa ttcaatagca tataatgata ccttgatgga gttatcaagt ttctttaaaa
    32581 gttatattgt aaaatttgaa gctcaggacg ttccagtaag tatagattat ccattggcac
    32641 tagatgatat ggatgttaag ggtatttatt atgtgaagaa ttatattgag agtatagata
    32701 tagaaaatag attttgtaac ctatttaaga aaaaagatag agaaaaatta ttttatgact
    32761 atggggtgac ttataaaata gattgtgatg ttatacttgt aaatttattt gaacttatta
    32821 tgaataattg tattttttct actattttag gaaatgaagt gactaattta gaaatttcaa
    32881 aatatgagta tgaattttta gaaaaacaat ttaaaaatat gtacaataat attactgaag
    32941 ataaagttat agactctgaa gaaagtaata taattgaatt gattgaagta gatgatagtt
    33001 ttaacactga agtagatagt aatttggatt ataatgattt tgaagaaatt aacagagaaa
    33061 ttagaataaa taaaaaaata actttactac ttatggaagc aattgaagta ttaataaaaa
    33121 gattaagcat agaagatgaa gatgtaataa gatatattaa aaaatatgaa aagatattta
    33181 ttgaatctgt gctaagctca ataaaaagta acacttttaa aagtatggta actgtgagta
    33241 aaaataaaaa tgaacactta gaagattata ttgttgatga tgaaagtaaa ttggatgatg
    33301 aatcgtttag agagatattc aatgagatat tagatagtac atctataatt gaaaaaataa
    33361 gaataataaa ggaaaatatc aatgctaaaa aagactttat cgatattctt gaatctgaat
    33421 gtttatttgg agaagagtat ttaatgttgt ttgcatcatt aagtgaatta gaattggcaa
    33481 tattgggtag tgtagtattt tatgaagata ttagaatgag agaaattaat atattagaat
    33541 ttatgttaaa tgagaaaact gaaactactt tatggaagat agagtacatt aaatttatga
    33601 agaggcaaag tgaagataag atatactcca tagaagagca tatgaataaa attaattaac
    33661 aaaaaattgt gaataaatag aatgttagta tataatataa tctgtaaagc atatcaaaaa
    33721 tacatatatt tggaggaaaa ttatgaaaga gtatatcata aataatgttg aagaaataag
    33781 agaagaatta attgatttat ctaagaaaat atgggaaaat ccagaattag cctttgaaga
    33841 aaagtatgca agtagcattc aaaaagaata cctaaagtca aaaggattta aaattgaaga
    33901 agtagaaaat ttacctactg gatttatagc aagttttgga gagggtaaac ctgtgattgg
    33961 catacttgga gaatatgatg ctttaccaga actatcacaa tgtgtaagtg cagaaagaaa
    34021 gccattggta gaaggaaaag ctggacatgg atgtgggcat aacctgttgg gtgtagcagg
    34081 tgtaggagca gttgtttcta taaaaaaatt aatagaagaa aataaattta atggaacaat
    34141 aaaatatttt ggttgtcctg ctgaagaaga aggtggagga aagacagtta tgtgtataaa
    34201 tggctgtttt gatgatgtag attgtgcatt tacatggcat ccttttgata taaatgcacc
    34261 ttggagagga ggaagtctgg caaacttatc tgtaaaattt aaatttaaag ggataacagc
    34321 ccatgcagct caagctcctc ataatggtag aagcgcactt gatgctgttg aaattatgaa
    34381 tgttggagct aattatttga gagaacatgt tattgactct ataagaatgc actatgttat
    34441 aactaatggt ggtggaagac ctaatgtagt tcctggattt gctgaaagtt ggtactttat
    34501 tagaggtaaa aaagcaaaag atgcagaaca cgttcttgat agattaataa aagtagctca
    34561 aggagcagca atgatgacag aaactgaaat ggagtataag gttacagatg gaatatatga
    34621 ctatatacca aaccaatgtt tgactgattt agtttatgac aatatggttt ttgttggttg
    34681 ccctaaaaat actcctgaag aagaagaatt tgcaaaaaag ttgtgtgata ctcttactag
    34741 agaagaaaga ttaggtgtag caacatcatt acaaaatgat aaatctattg tagaaagcta
    34801 tatacacaag gaaatagttg acggtgacaa agataaagga ctagctggtt ctactgatgt
    34861 tggagatgta agttatgtaa taccagtggc tcaatttgca atggcagctt ggcctgttgg
    34921 aattgcaagt catacatggc agtcatgttc atcagcaggt tcaaatatag gattttctgc
    34981 tatgataaat tcagctaaag tactggcttg tagtgcttat gatgtattta tggatactaa
    35041 aattattgat gaagcaaaaa ttgaatttga taaatcatta gatggacaaa aatttaaacc
    35101 attggtataa ttttggtaat aaaatatttc aggggggaat agctatgaga gaaaaagttg
    35161 aaaaagtgct tgaggaaaag ataaaaccag tattacaaag agatggtgga gatgtagagc
    35221 ttatagatgt aaatgaaaat ggtgtggttt tagttagact acaaggggca tgtagtgggt
    35281 gtccaggagc gactatgaca atcaaagcta ttattgaaaa tgttttggtg agtgaagttc
    35341 caggagtaac tcaagtatta ggtgtttaat agttagcgtt tattaaatgt atgttataca
    35401 taagtattta ataaagaagt aaaaaaaata gtgaaacaat atatatgaaa aagtatgaga
    35461 aagataataa aacattatag aaataatgaa atatttcata tgtatatgaa gaaataagaa
    35521 aaatagtgaa gcaatatata tatgaaaaag tatgagaaag ataataaaac atttatagaa
    35581 ataatggaat atttcatata tacatatgaa gaaatagtaa aacaatatat atatgaaaaa
    35641 gtgtgagaaa ataataaaat actatagaaa caattaaata ttctatatag gtattaagga
    35701 acatgaaaga aataatggag tattataaat aaatatgtaa aagtgtgaaa gaaggatgta
    35761 ggtaaatttg tcttatacaa atttacctac atccttcttt cacacttttt attttactat
    35821 ccagccatac caataaacat acctataaaa tatggaacta accatatagt ccatacaact
    35881 atactaaact tatgaaagaa ttttttcttt tcctcatcat ctttgtatag gacaaaagta
    35941 gcccaacttg catgaaaaag cataagcaca attgcaagaa gacctgtaat actatgaagg
    36001 ttttgtgata aagcagattt tacttcaaaa gtatggctgt tggctatgtt actcattgta
    36061 aatgttccta aagtatcaaa tataaaacca agccaaaata taattacatg tttctttttt
    36121 aaaatttttg cctttctttc tccaaataca cctatagtgt agaaaattaa agctgatgtt
    36181 ataaatacta ttgcaagtat taatttataa ttcataatta tctctccttt acttttgcca
    36241 atatatttct aagatttttt actaagtcac tcaattcgtt ttcatcacaa tttttaaaaa
    36301 tatcatcaaa actttcttgc attttaattt taaaatttgt ggcaaattca aatcctgttg
    36361 ttgtaaactt aacgtatgta tttcttttat cattagattt cttgaatttt tctatatatc
    36421 caatctgttc taatctgctg attatgcctg aaaccgtacc tttagctaaa gacatttcat
    36481 cacatagttg tgatattgta agttcttgat tatgagctat cagttttata actataatct
    36541 gttggtgtgt taatccattt tctttaaaat tttcttctac tgtgtacata gttttagaat
    36601 aaagttcttt taagagcatg gctattctaa aacagtcata attacttttc aataaaatca
    36661 cctcttaaat ggtttgcata caaactaata taatatactt ttcttatata gtcaacctaa
    36721 aattttataa ttttatagaa aataatgaag aatagaatat aaaaatttta ttttaggtat
    36781 aaataaaata atttgatgaa attttaacaa tttttaaaaa gtttgtttac acagttaata
    36841 aatgatgcta aaattaactc atagataaat atagaaaatt taattttgtt taatgataat
    36901 ggaaccacga aggttttaac gttactttac gtttgctttt atgtggtttt ttttattgca
    36961 acaaaggggg gttggggttt gttaaaggat atactgaaaa agttgttgca gtttatttta
    37021 gtaatgtttt tattatcttt tattgttttt tacatggcaa gacttgctcc aggagaccca
    37081 ttaatctctt actatgggga tggagtagaa agaatgagta cacaagaaaa agaaaatgct
    37141 atgaaaaaac ttggtttgga tgaaccaata tacagtcaat atataaaatg gatttcaaat
    37201 gcatcaaaag gggaatttgg aatttcattt aaatataaac aaaatgttac ttctgttata
    37261 aatgatgtct atataaacac tataatatta ggtggttcag gatatatact tacctttgtg
    37321 ctagccttat tgttaggaat attttgtaca ttacatgaag ataagctcat tgatagaatc
    37381 atatgcaaat taggaacaat aaccaactgt attccatcat tttgggttgc cttagtactc
    37441 atacttatat ttagtataaa cttaagtata cttccaagta gtggtgctta ttcaatggga
    37501 gaagagtcca gtatattaag taggatatca catctaatct tacctcttac agtacttata
    37561 ttaagccatc tatggtatta cacatatatg ataagaaata aattactaga ggaaataaga
    37621 gaagattatg tgcttttatg taaagcaaaa ggtttaaata atagaactat tgtttttaag
    37681 cattgcctga gaaatataat gccatcatat attagtatta tggccatttc gatacctcat
    37741 atactaggag gaacttatgt agttgaaaaa gttttttctt atcctgggtt aggaacactt
    37801 tgctttgaaa gtgcaaagta tcatgattat aatatgttat tagttttatg cttaataaca
    37861 ggggctttag tagtatttgg gaatatgtta gctcaaatta taaacaataa aatagaccct
    37921 agaatgaaat atgatagagg tgatactaat gaagccacaa tatagtgatt ttgaaattgt
    37981 aggagaaaat tatattttag tagcagaaga tgaacatata gaaacaaaga aaaccttatc
    38041 taaaaaaatt aaagaattac catatatatc aattattatt ttatcaatca tagtcattgg
    38101 aagtgtattc tcatctttta taatgacaca tgaaccaaca tacatggatt tagcaagttc
    38161 taatttagct ccaaataaaa cttttttatt tggaacagac tcaatgggta gagatatata
    38221 ttctatgata tggtatggag gaaaaatatc tttatttata ggactatttt ccactgtaat
    38281 atcaactgtt ataggaattg tttatggtag tataagtggt tcagcatctg aacttgtaga
    38341 tgatgcaatg atgaggttta cagaaatcat acttagtata ccttcaatat taattataat
    38401 atttgtacaa gctatacttg gaaattcaaa tccagtatct atgtccatag taatagggat
    38461 aacaagttgg atgaatatat ctaagatagt gagaacagaa gttagacaaa taaaaaatag
    38521 cgaatacata ctagcagcta agagcatggg aggaggattc ttctatgtat taaagcaaca
    38581 tttacttcca aattttgtgg catcaataat gttcatggtt gtaacaaaca taggcgcagc
    38641 tattggtact gaatcgacac ttagcttttt aggaattggt ttaccaatag aaattgtttc
    38701 ttggggaagt atgttatctt tgtcagagga agcattactt tcaaatagat ggtggattat
    38761 actgattccg ggtatatttt tggttaccac attggtgtgt ataacaaata taggtaatta
    38821 tataagaaag aataataata aaaaatctag taatttataa atcagcattt gagtattaaa
    38881 taagcaaata ctgaggtatt tgaaatatct atttaaataa atggggtcaa agctttgaaa
    38941 aatattttat aaaaagcaaa agggggagca tcatgaaatt aaagaagtta aaagttttaa
    39001 gtttagtaat gatacttagt ctaatggcag gttgttctag tggaggagac aaagataaga
    39061 aggcagatac gcctaaagat ggaaaggtgc ttgtttatgg aagtaatgac tatacaagta
    39121 taaatcctgc actatacgaa catggagaaa taaattcgtt aatatttaat ggattaacag
    39181 ctcatgatga aaataataag gtggttcctt gtctagcaaa ggactggaaa tttgatgagg
    39241 caacaaatac atatactttt aatttaagag atgatgttaa gtggcatgat ggagagaaat
    39301 ttacagcaaa tgatgttaag tttacaatag aaactataat gaatccagat aatgcttctg
    39361 agatagcatc aaattatgaa gatataacaa aaattgatgt ggttaatgat aatactataa
    39421 aaattacttt aaaagctcca aatacagcaa tgcttgatta tttaacagta ggagtattac
    39481 caaaacatgc tttggaaggt aaggatatag ctactgatga atttaatcaa aaaccaatag
    39541 gtactggacc atttaaactt gaaaaatggg acaaaggtca aagtataaca cttgttaaga
    39601 atagtgatta ttttgtaaaa gaaccaggat tagataaagt agtctttaag attgttccag
    39661 atgataaggc taaggcaatg caattaaaat caggagaatt agacctagct caaataactc
    39721 ctaaagatat gtctaacttt gaaaaagacg aaaagaattt taaagtaaat ataatgaaaa
    39781 cagccgacta tagaggtata ttatacaatt ttaattctaa attctttaaa gataaaaaag
    39841 ctaaaggatt accaaatgct ttaagctatg caatagatag aaaagcaata gttgacagtg
    39901 tattattagg acatggtgta ccagcatatt cacctttaca aatgggacca tataataatc
    39961 ctgatataga aaagtttgaa tataatccag aaaaagctaa acaagaaatt gaaaagctag
    40021 gttggaaatt aggttctgat ggaatctatg aaaaagaagg tactaagtta gctttcgaga
    40081 taacagcagg tgagagtgac caagttagag ttgatatggc taaaatatgt gcacaacagt
    40141 taaaagaaat tggtgttgat gctaaagctg ttgttgtaac tgaaacagat tgggctaatc
    40201 aagatgctca tttaataggt tggggaagtc catttgaccc agatgaccat acatataaag
    40261 tatttggaac agataaaggt gcaaattaca gtgcttactc taatcctact atagataaaa
    40321 tacttcaaaa agcaagagaa acagaagata aagatgaaaa attaaagtta tataaacaat
    40381 tccaagtaga aatgactaag gatatgcctt atacatttat tgcttatata gatgcaatat
    40441 atgttggaaa accaaacata aaaggattaa cacctgatac agttttaggt catcatggtg
    40501 taggtatatt ctggaacata gctgactgga caattgaata atactgaaat taattagaaa
    40561 ccttagggat aaaaatatat ccctaaggtt tgaatagcat aggggttgat ggtttttgga
    40621 acatttattg gaggttaata atctatctgt aagttttaaa gtagaagaag gagaagttca
    40681 ggctgtaaga aatgtatctt ttaatctaaa aaaaggtgag acattggcta tagttggaga
    40741 atctggttgt gggaaatctg tactgtgtaa gagtttgatg aggatactcc catacaatgg
    40801 atatattaaa aatggagagg ttttacttaa atcaagtgat ttggttaaga agtctgaaaa
    40861 agagatggaa gatataagag gaaagaatat atcaatgata tttcaagacc ctatgacatc
    40921 tctcaatcca actatatcaa taggaaagca aattgcagaa gctgtaatca ttcatcaagg
    40981 tataagtaaa agtgaagcaa aaaagagagc catagagctt attgaattgg ttggaattga
    41041 taatcctgag aaaagattta aacaatttcc acatcatttt tcaggtggaa tgagacaacg
    41101 tatagtaata gctatagcac ttgcctgtaa tccagatgta ttgattgctg atgaacctac
    41161 aactgcttta gatgtaacta tacaagctca aataattgat ttaataaagg atttacaaca
    41221 taaaataggt ttgtcaataa tatttataac tcatgattta ggagtagttg caactatagc
    41281 tgatagaata gcagttatgt atgcaggaaa gattgtagaa ataggaactg tagaggatat
    41341 attttatgac cctagacatc catatacttg ggggttgttg ggttcattac ctactttaga
    41401 ttcgcaggat gactatttat ataatatacc tggaatgcct ccaaatttat tgaacccacc
    41461 aaaaggagat gcttttgcaa taaggaataa aaatgcactt aagatagatt atgaaaaaga
    41521 gccaccaatg tttaaaatta atgatacaca tagtgcagca acttggttat tgcacccaga
    41581 tgcacctgaa gtagatgtac cagttagagt aaattgtgga agggtgattt ctaatgaata
    41641 gagaaaaaat actggaaata aaaaacttaa agcaatattt tcatttggac aaaagtacta
    41701 ctgtaaaagc agttgatgat ataagttttg atatatataa gggtgagata tttggattgg
    41761 taggagagtc gggttcagga aaatctacaa ctggtaaaac tataataaga ctacatgaat
    41821 ctactggtgg agaagtaatt tacaaaggaa attgcatatc agataaaaaa acgtacaaat
    41881 ttataaaaaa agatgtaaac aaaagtatgc agattatttt tcaagattct acttcatcat
    41941 taaatccacg tatgacaatt gcagatataa tttcagagcc actaaaaatt caaggtatct
    42001 gtaaaaataa aacagataga atgaataaag tatatgagat gctaaagcta gtaggacttg
    42061 atagaagtta tgcaaataag tatccatctg atttttcagg tggacaaaga cagcgtattg
    42121 gcatagcacg agctctttca gtagacccag aatttataat agctgatgag cctatagctt
    42181 ctttggatgt gtctatacaa gcacaaatag taaatttatt taaaaaattg caacaagaaa
    42241 agaatttaac ttgtttattt atagctcatg atttatctat ggtgagacat attagtgacc
    42301 gtataggagt tatgtataat ggaaaattag tagaattggc agattcaaat gaattgtata
    42361 ataatcctat tcatccatat acaaaatcac tactttctgc aattcctgtt cctgacccta
    42421 gatatgctaa gtcaagaaat agaatagagt ataattctaa tggatatgat tgttcaaatg
    42481 aaaagtcatt aagttggatt gaggtttcag atggacattt tgtatattct tctaaatcag
    42541 aaataaataa atatcaacaa aatttaaaag ttgtttagta taaaaatact tgaacaggta
    42601 tttatttgaa atacaaacta aaaccctatt tttggagaaa ttttaaaact actccaaaat
    42661 agggtttttt atttctactt ttcaaatata ataaattcaa atataataaa attaaaaaca
    42721 agtaaagtat gttgttaaga aagtactata aaattaaaaa tagtaatgta gaaaaaatga
    42781 gcaataatct tattttttct acaataattt tctataattt aaagtaagga aaatttgata
    42841 aattataacc ttagttaaag aataagagtt tattaaaaaa taaagtgtgt ataggggttt
    42901 tagttaataa aatactataa tgtaggggag cttgtaatga tatataaaaa agataaagta
    42961 atgaaagttt tagaatcatc atatagggaa aatgaaaaag ggattacagc taaccaatta
    43021 tcagaaaaga caggaattgc aagaaacaat ataagtacat atttaaacca attattcaat
    43081 gagggtatgg ttacgaagat aaaaggaaga cctgtgtatt atatccctgc aaatcttaac
    43141 cttaacaaga atgaattgct tgatacacaa agtgagttgc ttggcataaa aaaaggaaca
    43201 aaagtagaaa acaaaataaa aaaagatagt tttgaaacac taataggtaa agaacatagt
    43261 ttaagaccta taatagaaaa atgcaaggtc gcaatgctct atcctacaaa tggacttcat
    43321 actattatct atggagaaac aggagtagga aagagtatga ttgctagata tatgtacgat
    43381 tattctatag atagtggaat tagaaaaaat aaagctcctt ttgtaacatt taattgtgct
    43441 gattatgcta ataatgcaca attacttatg ggacatattt ttggggtaga acaaggagct
    43501 tatacaggtg cagaatcttc cagaaaaggt cttttggaaa ttgcaaatgg agggatacta
    43561 tttttagatg aaattcatag actaccagca gaaggtcaag aaatgttgtt tacttttata
    43621 gataagggaa catttaaaag actaggagat gcaacgaaag aaagagagtc taaggtatta
    43681 ataatatgtg ctactacaga aaatccgaca tcaacactat tagatacatt caatagaaga
    43741 ataccaatga aaatagaaat accatcattg agagatagga caatgattga aagaatggaa
    43801 ttagtcaaaa attttttcaa ggaagaatca aaaagtattt ctatttcaat aaaagtacat
    43861 aaagaaataa ttaaatcact attactttat gattgtaaaa ataatgtagg tcaacttcaa
    43921 aatgatataa aattagctgt tgcaaatgga tatctaagat ataaaagaga taataaagaa
    43981 ccagtttata tagagaaaaa atattttgat aaatctataa atgaagtgag tgatgattat
    44041 agagagaagt ctattaaagc agatgaagtt ataacacatg gaatagaata ttttgtattt
    44101 acgtcattag gagaagaaga agttattaac tacaatgata taaatattat taatgcagta
    44161 aatactaatc ttaataaatc tgtagaaatg aatatagcag atgcttctct atttaataat
    44221 gttaagttta aaagcatgtg tgaatcaata agacaaatta ttaaagaaga tgaagaaata
    44281 gacataagtg aatcaatatt taagtcaatg gcaatttata taaaaagcgt attggataaa
    44341 agtagctcta caaacaacat agatttgaat caaattagaa gaaataacag aagtgaattt
    44401 aaaacagcat taaaaatagt tggaataatt gaaaatgaat ttgatttatt tttatctata
    44461 gaaactgtag catatattac attattcata gtacaagcta aacaagatga acaaaataaa
    44521 atagtgaata acattaatat tatagttgct atgcatggag aaactacagc aagtagtatg
    44581 gtaaaagcag ttggtgatat tattggaaag tgcagtgcta tttctttcga tatgaagtta
    44641 gataaaagct atgatgaagt aattgtagat tttaaaaatt taattaataa tatagacaat
    44701 aaagatgtat tactatttac agatatgggt tcattaaact cttttgatga aattataaag
    44761 aaagaaaaaa agtgtggagt aagagtaatt cctatggtga cgacattaac tgtgttagaa
    44821 gcagttcaga aggccaatat gggattacct ttaaatgacg tatacaactc tataactaac
    44881 acgagaaagt actattttgg aactaatgaa attcaaaata aagaaaatct gtctaaaaca
    44941 attattatag catcacatgt ttcagaaggt gtagataata aaacaagaaa aatattagaa
    45001 gaaaagatga gtaggtactt agatggaata gatattatat ctgtcccata taaaacagaa
    45061 aaagatttaa gtttaaatat tacgaaactt aaagaaagta gtaatattgt tgcagtaatc
    45121 aatgaacaaa gaattaatat tagaggaatt gactatatta gcaaaaaaga tatagataag
    45181 gatgaaaata tcaataaatt aaaaaatatt ataaagataa gtataggtta tgatgatgta
    45241 gttgaaggtt taaagacatc cttaaaaagc tctaattata ataggatatt taaaggtata
    45301 aaatatgtgt ctgatgaatt gtttttagta tttaatatag aaaagaaata cgataaagta
    45361 attggactta tgatgcattt agctttcatg gtagatgggt tgattggaaa tactagagaa
    45421 attgaaaagc ttgataaaga aaaaacactt gattatcaca agagtctaag caaaataaaa
    45481 gatatagtat ctcaattaga taaaaaatat aatatagaaa ttaatgaaaa agagtgctat
    45541 caaatattat taatattaga atatgcagaa ataatcgaaa aagattacca atgagtataa
    45601 aaacttattt ggtaattttt tttagtctaa aataatatta atattagaca catataaata
    45661 tacttagaca aagtatctaa gttttgatga taaaaatgat tgaaataaca gtgttttaaa
    45721 gtgtctaaaa aaactggcat aatacttgct tatattatta aatgagcaat ataaataatt
    45781 aaaatttaaa taaaaaggag taaataatat gcaagataaa atattaagag ataaaaaggc
    45841 aaatgaccca tgggcaagaa tgactacaag aaacggattt agtgcagacg aaataatatc
    45901 gtcatttcaa aaagctataa gaagaaatat ggtggaagaa gcttgtgaat ttgcttatga
    45961 actatatata tcatcaccag aattagaaga taagctatgg agaaggatac ttacaatatc
    46021 agttgaagat ataggaatgg gggacccatc agctgtaata atcataaata atttaaatca
    46081 agtaagaaag gaatattcat atgcagatgg agacagacct ttatttttca tacatgcaat
    46141 aagatatctt tgtgcatgtg agaaagatag atcaagtgat ttattaaaaa atataattat
    46201 aaaaggattt gcaatgggta aagttccaga agttatggac gtggcacttg acaagcatac
    46261 atatagagga ttagaaatgg gaagggattc attccacttt ttaaatgaag ctagtatagt
    46321 aataccagaa aaagaagtag ataatgatta taaagaaaga tacttaaaaa tattagaaaa
    46381 atataagcaa gaagaagtta tagatacggc tttcaagttt aatcattggc agtactaaga
    46441 attagagtaa atattaataa gaattaaaat aaaataataa gaattaaagt aaaaactgat
    46501 aggaattaga gtaagaattg gctgataaaa aattagaaaa caaaagaggt tagatattgt
    46561 aggagggtaa ttatgaatat tttattagta tgtgcaaatg gagcttcaac aggtgtactt
    46621 gtggaaaaga tgaaaagttt ttgtagtgag catgaaaagt taaaaactaa aactataaat
    46681 atagaggcaa catcatttga aaatttaaaa tcatacattg aagctaatga tacagatgta
    46741 gtacttgtag caccacaaat taggtttaag gaagatgatg tagttgaagc ttgtaagaat
    46801 tacaaaatag cagttggttt aatagatact aagcattatg gtcgtatgga tgctccttct
    46861 gttatgaagt cggcaatcga attatataaa aatagataat tggggggaat aaaaatggaa
    46921 gcacttcaaa ataatttaag aagatttctt cttccaatag cacaaaagat tgaaaaacaa
    46981 aggcatcttc aagctataaa agaaggtatg ataagcatta ccccaataat aattgttggt
    47041 tctttaagta tgttatttat ggcattaaac aatatgttac ctgaaggaag tgcaaaaaca
    47101 ttattatctg aaaatatgga tacattactt atccctaata aatttactat gagtttatta
    47161 tctatatatt cagcattttt tatagctcag gcactagcta aaaaatataa tcttaatcat
    47221 gtagaaatag gtatgacagc agttgttgca caacttgttg tatgtggaca agtagtagat
    47281 ggtgtattag atacaagtta tttagatgca caaggtttat ttgtaagtat attagtagca
    47341 cttttagtag ttgatattac taagtttatg aatgataaaa atctcgtaat tagatttcca
    47401 aaagaagtac ctagtgtagt aaataaaagt tttagaaact taactccaat gatagtatgt
    47461 ataatgttat ttacagcaat agcagcaata actaaaaatg tctcaggtca accactacca
    47521 gctattataa tgaatttctt agcaccagct ataagcagtg tagataatgt ttttgcagta
    47581 actataatac tatttataac tcaattatta tggttctttg ggcttcatgg agcagcaata
    47641 acttcaagta tatggatgcc aatagcagct acatatatgg cagaaaatgc aacactgata
    47701 gcagcaggag gagacccaaa atatgtgttt acaataggat tttactatgg tttcttgcaa
    47761 gtaactggtt cagggataac tttgggatta gtgtacctta tgtcaagaag taagtgtaag
    47821 agttttaata gtatgggaaa agttgtgatt ttaccatcac tatttggaat aaatgagcca
    47881 gtaatatttg gaacaccaat agttatgaac ccatatatgt ttgtaccatt tgtatttgga
    47941 cctgtattgg ttggagcact taattttatg gcattaaaag taggattagt aggattacct
    48001 attgcagaac caccaggctt tttacctcca ggggttgcag catttttgat gacattagat
    48061 tggaaggcaa tcgtattagt atttgcaagt ataatactta tgaccttgat atattatcca
    48121 ttctttaaga taatggagaa ggaagaatta aataaaaatg cagaattagc tacaacatta
    48181 gatgatgata gctttgattt ttaacaagtc attagaagga gaaggatatg gtacctgaaa
    48241 tggaagaaaa agtatttagt ataatatcag aagcaggaga tgctaaaagt gatgtaatga
    48301 tgtctcttaa ggaaataaaa aaaggtgact acaataaagc aaaacacctt ttaaattcag
    48361 cctcagagaa aatacaaaca gcatcaaagc atcatttaga attactatca aatgctatga
    48421 atagtgaaga tagtgggact gattttttag ttgtgcactc tgaagaccat tattcaaatg
    48481 cattatttgc tcattcttta gtatctgaac ttgtagatat atttgagatg atggacccaa
    48541 gaattaataa gaattaaatt tcttgtaaat agtgcttgaa gtttggctat agtttattaa
    48601 atcaatagat ttaataaatg aactcccttt tactttaaag tactagtatt tataaattta
    48661 tttataaata cagtaaattt ttaaatagaa aaggagatat tattatggaa aaattttcag
    48721 tagtaatagc tggaggagga agtacatata ccccagaaat catattaatg ttgctagata
    48781 acttagatag gttaccatta agagcaatca aattatatga taatgatgaa gaaagacaaa
    48841 ataaggtagc taaagcttgt gaaatactaa taaaggaaaa ggaccctaat atagagtatt
    48901 tagcaacaac atgccctaaa gaggcttata cagatgtaga tttttgttta gctcatataa
    48961 gagttggaaa acttgaaatg agagaactag atgaaaagat acctctaaaa catggagtag
    49021 ttggtcaaga aacttgtgga ccaggtggaa tagcttatgg aatgaggtct atagaaggtg
    49081 ttcttgaaaa catagattat atggaaaagt attctccaaa ttgttggatg ttaaattatt
    49141 ctaatccagc atcaataata gcggaagctg ttagaagatt gagacctaat tctagggtaa
    49201 taaatatttg tgatatgcca ataggtatgg aacataatat agcaaggatt gcaggactca
    49261 aatctcgtaa acatatggat ataagatact ttggattaaa tcactttggt tggtatactt
    49321 caattaaaga taaaaaagga aatgaacttt taccaaaatt agtagaacat ataaaagaat
    49381 atggttttat aaatggtgaa gaaggaatga aaaatgacaa gaaagatagt tggtttgaaa
    49441 ctaatttatt tactaaagaa atagtaaaaa cagatttaac tacaatacca agtagttact
    49501 taaagtacta tctatttcca gattatgttg taaatcattc tgatgtaaat tatactcgtg
    49561 ccaatgaagt tattgatgga agagaaaaag aagtttttgg ttcatgtgca ttgatagaaa
    49621 agcaaggaca ttctaagggc agtgggctta agataggaat acatgcagag tttatagtgg
    49681 atttagctac agctctagct tttaatacac aggagcgtat gttattgata gttcaaaata
    49741 atggagctat agaaaatata caagatgatg ctatggttga aattccatgt atagttggaa
    49801 aagacgggta tgaaccatta tcaataggga aaataccaac attccaaaaa ggtttaatag
    49861 aacaacaatt agcagttgaa aaattagtag ttgatgcttg gattgagaag tcttataata
    49921 aattgtggca agcacttatg ctatctaaga cagttcctag tgcaacagtt gcaaaagaat
    49981 tactagatga tttaatagaa gcaaataaaa attattggcc aaaacttaat taagaataat
    50041 atatttttaa agttcctaca gtttagtaca tagcttagtt aatgtatttg tagggacttt
    50101 atttatctac aaatgagata caagtggaaa acatagtgta ttttgcagtt aggaaagtag
    50161 gtttagttac ttgttagttg gattaaattt agatacaata atttactatc aatcaataga
    50221 aataaccaga gaagttgcat aataaaaaat ttacactttt aacaggattt atgtaggtgt
    50281 ttatagaaat aaataaatat gtacataaat acataattat ttttaagtct aaaatacaag
    50341 aatggagaga tggctatgaa gtggagagat tatgctgatg atgtaaattt atttgaggat
    50401 tttgataaaa ctatcaagcc tctaactgac gaacaaagaa gaaaaaatat aaacacttta
    50461 attgcatatt tttcaaaaga agttccttct aaaatataca atttatcaaa tgatgaaatt
    50521 aagcctagag atatacttag aggacttttg aatgtatatc caccaaaaga aattgctcca
    50581 gagatactta atatgttaca taatttattg ttgattgaat gtgaagaaag agagttaata
    50641 gatgtaaatg atatagaaga agtagaggaa gggattgcca tatggagagg taatataacg
    50701 aatttaagag cagatgcaat agtaaatgct gcaaataaca agttattagg gtgtttacaa
    50761 ccattacatc tatgcgtgga taatgagata cattcatgcg caggtcctag acttagagaa
    50821 gattgtgaca aaataataaa aaaacaaggg catttagaat atactggaga tgctaagata
    50881 actagaggtt attgtttacc tgcaaaattt gtagtacata ctgttggacc tattgtatct
    50941 ggtggtcagc caagtaaaga gcaagaaaag caactgcttc attgttataa atcatgttta
    51001 aatacaataa aagaaattga tgaaataaaa aatattgttt tttgtggaat ttctacaggt
    51061 gtatttggtt atccaaaaaa agaggcagct aatcttgctg taagtagagt tagactatgg
    51121 ctaaaagaaa atcctgaaaa aaatttaaaa gttgtattta atgtgtttac tgaagaagaa
    51181 gaagagaaat atagaagaat atttaaataa tattatgtaa cagaatccta aaaatactta
    51241 ttatataata caaattcatt gtataagata ataatttaca agtagtaaaa attaataaaa
    51301 tataatttgt atttttaata aataagtagg tataatagaa attataagaa tagtataatc
    51361 aattatgc
//
LOCUS       DAMKNB010000242        40706 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.guided.032, whole genome shotgun sequence.
ACCESSION   DAMKNB010000242 DAMKNB010000000
VERSION     DAMKNB010000242.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 40706)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40706)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40706
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.guided.032"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            321..659
                     /locus_tag="PC494_003791"
     CDS             321..659
                     /locus_tag="PC494_003791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF3914192.1"
                     /translation="MANIGKIIGDRIKVYRTKLGYSQEFLAEKAGLHPTYIGQIERAE
                     TNTSINIIMKIATALDIPLELLFANIITTEGVDNSVPLECYEMINKLTEKEQIAMLEL
                     IKCIIKYKEI"
     gene            681..998
                     /locus_tag="PC494_003792"
     CDS             681..998
                     /locus_tag="PC494_003792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF3914193.1"
                     /translation="MNYIGKRLKEERKKANLTSKEFANMVGVSPWYITQIESGKKNPS
                     LKTFIKFVNILNISADVLIKDITSTGKTYLENDINEELKDLNSRELNLISQIIDIIKK
                     NKI"
     gene            1148..1825
                     /locus_tag="PC494_003793"
     CDS             1148..1825
                     /locus_tag="PC494_003793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3914194.1"
                     /translation="MIVIEGSDKFKIAKEYIDVEYTLFSKVTFRYEKLKFKDNAELEK
                     IKMFKYKNGYIPNKLNLSFGYGFSSYKKQIIRETVDTLRLTEIFSSENIEDIKFIKDG
                     TKKLEISIEKVVKFKRRKKRNYVCCYCPDMYRDIKLDKESINKIYNRKIKIEREVNIF
                     EDEDVIINKKVLKFPKSWTKNMQKYWLSENKYPIHSTVIDDDRYKCCNVQYTKNRVII
                     LYYIYNH"
     gene            complement(2158..2925)
                     /locus_tag="PC494_003794"
     CDS             complement(2158..2925)
                     /locus_tag="PC494_003794"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HDF3914195.1"
                     /translation="MKRKVQVKNITIGEGRPKICVPIIGKNKKDIIKEAKELKDACLD
                     IIEWRVDFFENVENIKEVKEVLYELRSYIHDIPLLFTFRSVVEGGEKLISRDYYTTLN
                     KEISNTGLVDLIDVELFMGDEVIDEVVNFAHKKEVKVIISNHDFNKTPKKEEIVSRLC
                     RMQELGADLPKIAVMPQNEKDVLVLLEATNEMFKIYADRPIITMSMSGMGVISRLCGE
                     IFGSALTFGAAKSVSAPGQISFKELNSVLNLLHKSIN"
     gene            complement(3596..4411)
                     /locus_tag="PC494_003795"
                     /pseudo
     CDS             complement(3596..4411)
                     /locus_tag="PC494_003795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897377.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
     gene            4503..5171
                     /locus_tag="PC494_003796"
                     /pseudo
     CDS             4503..5171
                     /locus_tag="PC494_003796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331151.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
     gene            5298..5918
                     /locus_tag="PC494_003797"
     CDS             5298..5918
                     /locus_tag="PC494_003797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HDF3914196.1"
                     /translation="MHLIDFMNEDIKKKLVKKTYKKKETILFAEQENEYVILMIDGIA
                     EAFILNVKGNISTIHLYRSGSFFGEMEQFNDGKKPVEIVAFTDCNVYKLHRDDFLNWL
                     RGDFEATKFLIREISSKLVVNAELIEELSSLSVKERLLRCISLHYYRSELNLLTKKQL
                     ASEVNAPIRSINRAINECVQEHLIAYENKRFSVINQREVLKNLPTT"
     gene            6074..6856
                     /locus_tag="PC494_003798"
     CDS             6074..6856
                     /locus_tag="PC494_003798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside 6-adenylyltransferase"
                     /protein_id="HDF3914197.1"
                     /translation="MTKTQQEMIQNVLEFSKRDSRIIGLAISGSYITKSLDEYSDLDF
                     LIVADDKSYEEVIEERLLIVEQFGTLVSAFTGEHVGEPRLIISLYDSPVLHVDFKFTT
                     LDGLLDRVEDSAILYEENNCITEIYSKKEAYFPTPDLQWIEDRFWIWVHYTCTKIGRR
                     ELFETIDFLSFLRQSVLASLIQLLLGKLPRGVRKIELDAPQYIEALEKTVANHEYKSC
                     VNALQATINLYLELREELSQSPIVRKVEAERVALQYFQDLIK"
     gene            6981..7907
                     /locus_tag="PC494_003799"
     CDS             6981..7907
                     /locus_tag="PC494_003799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3914198.1"
                     /translation="MSDILSRITNKIGDKNIVDKLSALSKSDLNSLLLEVFDRQANTL
                     TATDILKSYQLNRFTIPSGIDPEEIHALESKLLRKAFNMDIKTIMLSPSAPLGSCSVF
                     GSVDQYNVVSALRGTETLADPSNMLAIIIADKLKRKEENNTIPIHMATTARVIRAQNF
                     VGKGLYSHFGLYCMVSSGIDTGSYTCEKMLLEKHLNYYKDILSEIENVRFSIILRKRN
                     GYKDNDGFFDRMVETIKLIFPNIELSIHNDDVDNNYYKGINFKLSVKQGNETVEIVDG
                     GFVDWTYQMLGNKKERCLISGIGLERFLVAVS"
     gene            7921..8359
                     /locus_tag="PC494_003800"
                     /pseudo
     CDS             7921..8359
                     /locus_tag="PC494_003800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729090.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            8720..9127
                     /locus_tag="PC494_003801"
     CDS             8720..9127
                     /locus_tag="PC494_003801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HDF3914199.1"
                     /translation="MVDEKTIEHQFDSFCKTVLRNYARDIYDENKRRNDYLVSLESLS
                     LAELSKLSILDDYDSNYICMVSYDYNIRIEDVLMAQAIGKLTKRKQDIILLSFFLNMT
                     NADIATLMDLAENTIHYHKTNALKELKELMQEH"
     gene            9129..9359
                     /locus_tag="PC494_003802"
     CDS             9129..9359
                     /locus_tag="PC494_003802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF3914200.1"
                     /translation="MKPTKEVLPFTIILLAVHGDVNAINVILKHFEHYIIRLSQKTLF
                     DEYGNPYIHVEEETKRMLGTKLITAILRFNLS"
     gene            complement(9547..9684)
                     /locus_tag="PC494_003803"
     CDS             complement(9547..9684)
                     /locus_tag="PC494_003803"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3914201.1"
                     /translation="MVFQPIPFLWAEPCHTGVSLYCGTGYGKTTVPKVIHKSLYSSSL
                     D"
     gene            9749..9952
                     /locus_tag="PC494_003804"
                     /pseudo
     CDS             9749..9952
                     /locus_tag="PC494_003804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262306.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
     gene            10030..10383
                     /locus_tag="PC494_003805"
     CDS             10030..10383
                     /locus_tag="PC494_003805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integrase DNA-binding domain-containing protein"
                     /protein_id="HDF3914202.1"
                     /translation="MSTEKRRDNKDRILRTGESQRKDGRYAYKYVYSFGKAQFVYSWK
                     LVPTDKPPKGKRDDISLRDKEKAIQNDLDDSIDTIGKKMTVCQLYAKKNVLRKNIRLN
                     TKKGRHYLMKILNKE"
     gene            10455..11087
                     /locus_tag="PC494_003806"
     CDS             10455..11087
                     /locus_tag="PC494_003806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CatB-related O-acetyltransferase"
                     /protein_id="HDF3914203.1"
                     /translation="MTIPSSNKVYPRSNDYQTVYLKNVITRENIEVGDYTIYNDFYND
                     PRDFEKNNVLYHYPINNDKLIIGKFCSIACNAKFLMTSGNHSMKSKSTYTFPIFYEEW
                     KLDINHITDAWDNKGNIIIGNDVWIGYDSIIMSGVNIGDGAIIGTRAVVTNDVPPYSI
                     VGGVPAKIIKKRFNNDTISKLLEIKWWDWPYKKIQSNIKHIQSGNIDKLV"
     gene            complement(11458..12327)
                     /locus_tag="PC494_003807"
     CDS             complement(11458..12327)
                     /locus_tag="PC494_003807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HDF3914204.1"
                     /translation="MEYDMPLYRPPSEAYSLIIQVTLGCSHNKCTFCSMYKSKKFKIK
                     PLEVIKNEIDIFRRYYKHVERIFLADGDALIIPMEKLRDIILYIKEVFPECERITMYG
                     SPKSIEKKSDDELKELRKLGVKMIYLGLESGSNEVLEDIKKGFSSEQLIKVGRKVKKS
                     GIKLSATVIAGLGGTKKTHQHAVDTGKMLGAISPDYVGVLSLMVEPNTELYDLLKAGE
                     FTILEDKAVLQEIKEMIKNIDANEKIVFRSNHASNYANLKGVLPDDKQRLIDEIDYYL
                     SNQKLKREEYRRL"
     gene            complement(12424..13281)
                     /locus_tag="PC494_003808"
     CDS             complement(12424..13281)
                     /locus_tag="PC494_003808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDF3914205.1"
                     /translation="MSKDVKVKRNKKYDTFSITMELERPLLYDEVENKDDKNNNRKFN
                     IKNKIFKGIGILFVLILLGFFIWINKTYEPQKLAKEALVSNSKVEVTVNENISFTPKG
                     RKVSKGLILYPGAKVEIESYAPLARKIAESGYEVVIVKMPLNLAILGTNKAQKVMDSY
                     NNIEHWVIGGHSLGGVAASNFARDNKLIEGVVFLASYPMGDELKELGKKVISIWGSKD
                     GVVNFKSLVESKQKLPDDTTYVEIEGGNHAQFGDYGKQKGDNDAIISQEKQLNITANS
                     IIKFLKNIS"
     gene            complement(13495..15513)
                     /locus_tag="PC494_003809"
     CDS             complement(13495..15513)
                     /locus_tag="PC494_003809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HDF3914206.1"
                     /translation="MTKKLVISKTKLFIFIIAFISIFIYLFGSKNTLIGVGIVTAMLT
                     LLERDLTISPIKNLLKYLAINIILGILSFFAVQNMYLGVLLNFIALFIIGYVFSYDLK
                     RAVYVPFGLMYIFMVSIPVGKSEFPMRLSALAVGAVIIMIAQFVMNRNRMKNVGDKEL
                     ISICDELLEKISLLKNTINDDSSIIKSSMRKIDSCNYRINSISKNLKMVIFDNRKDDF
                     YISIRGIDIMNILFSLERISLILERYKKDSKEFEDEDIKNILEESSINSKSDVLVVAT
                     KEINYIKMCLENKDTITDKEILGFRDYVISQDTKNINLKEIYSVLENLYEFLVDYKKV
                     KSRDEKKAERKSKIPHEFKRLSIYKKNFNLNSIRFSYAVKIALATAVAGFIMDYFHLR
                     DGRWIMLTVFSLTQPYAENCIQRSRKRIEGTFIGAVIFIVLFSIIKDSTLRSLIVLLA
                     GYINSYVVDYRKLMVCVTVSALGSAVVMGDPNVLTISRISYVALGAIIALIVNKFILP
                     YDAKTGYQHVIEMYKGIVKNIIDEVNKSIENVADVYYIKNLLLIPSLIEDRLMLINAI
                     YKDKHQEDFLENQKLLISNMYNLYINVNKNKIKDEDVEKILRDTNYISNYNVDKYDEG
                     RSVILESIVNTKSLGDKIICLNLLQTLNGVKEMYRISNITKVSIKEAA"
     gene            complement(15784..16560)
                     /locus_tag="PC494_003810"
     CDS             complement(15784..16560)
                     /locus_tag="PC494_003810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HDF3914207.1"
                     /translation="MHKETLDKLTNAAINKINLLNTSKVKYLVSSAFAGLYVGIGILL
                     IFTIGGLLTDAGSPMTKIVMGLSFAIALSLVIMTGTELFTGNNMVMSAGMLNKGVSIK
                     DTSKIWAYSWVGNLIGALVLGIIFVGTGLVDKGPVAEFFANTAASKASMPFTALFFRG
                     ILCNILVCVSVLCSFRTNSDTAKIIMIFLCLFAFITSGFEHSVANMTIYSVSLFSPTI
                     STVTIGGAIYNLVAVTLGNIVGGALFMGLGTYILGKEKLN"
     gene            complement(16617..17588)
                     /gene="asrC"
                     /locus_tag="PC494_003811"
     CDS             complement(16617..17588)
                     /gene="asrC"
                     /locus_tag="PC494_003811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite reductase subunit C"
                     /protein_id="HDF3914208.1"
                     /translation="MIRDLNTKKVMKNAYRITKTKYETSLRVRVPGGLIDPESLAVVS
                     KIASEYGNGQVHITTRQGFEILGINMEDMEEINKIIQPVIEKMNINQSEKNAGYPAAG
                     TRNIAACIGNKVCPKAQYNTTEFAKRIEKAIFPNDLHFKVALTGCPNDCIKARMNDFG
                     IIGMALPIYEKDRCVNCGACVKKCSKISVGALKTENNKVVRDKDKCIGCGECVLNCPT
                     NAWTRDEKKYYRLAIMGRTGKKNPRLAEDFLLWVDEDSIIKIILNTYRYVEKYIDKDA
                     PGGKEHIGYIIDRTGFMEFKKWALEGVELPEITKMYENIYWSGIKYL"
     gene            complement(17601..18392)
                     /gene="asrB"
                     /locus_tag="PC494_003812"
     CDS             complement(17601..18392)
                     /gene="asrB"
                     /locus_tag="PC494_003812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic sulfite reductase subunit AsrB"
                     /protein_id="HDF3914209.1"
                     /translation="MNPYIPVSAKILDIVKHTDKEWTFRVNCNTKGVLPGKFYEISIP
                     KYGESPISVSGYGEDYIDFTIRNVGKVTSELFNYKEGDSFFIRGPYGNGFDVSLYEGR
                     EIVVVAGGSALAPVRGIVEYFYNNKEKCEKFKLIVGFKSPKDILFADDLKRWSKKLDI
                     LVTVDGAEEGYSGNVGLVTKYIPELDMKDINNTSIVVVGPPMMMKFTVEEFLKRDLDE
                     KNIWVSYERKMCCGIGKCGHCKMDDTYICLDGPVFDYSYAKNLID"
     gene            complement(18393..19400)
                     /gene="asrA"
                     /locus_tag="PC494_003813"
     CDS             complement(18393..19400)
                     /gene="asrA"
                     /locus_tag="PC494_003813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic sulfite reductase subunit AsrA"
                     /protein_id="HDF3914210.1"
                     /translation="MKLKLDSSKFNEGLNYLKKDYKIFAPVLIPFKGTFSDTDVIRYK
                     EVNAFEEMEFAKKANFSPKEVVLPINQVLFYFTEKEFKESDLDNKKILIFLRACDING
                     IKRLDEIYLNNGEEKDYFYKNIRDKVKFALVGCKESFRNCFCVSMDSNKTDNYSIGLN
                     IEGDTLYLDIKDSEFEVFNGEATEFNVDYVTDNLISVDVPENIDSNEMIGNSIWDEYD
                     TRCIGCGRCNFVCPTCSCFTMQDIFYKENENVGERRRVWASCQVDGYTDIAGGNSFRK
                     KQGERMRFKTMHKIHDFKKRFGYHMCVGCGRCDDACPQYISFSKCIEKINDLVISKEE
                     V"
     gene            complement(19791..20480)
                     /locus_tag="PC494_003814"
     CDS             complement(19791..20480)
                     /locus_tag="PC494_003814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HDF3914211.1"
                     /translation="MSKLKDYNIDKVIIFNNLSTKTKNQLKEKVKLKRLQKKEILFYE
                     KDSLDSVYILLEGKVSIFKISENGERKVIFILNSGEVINDITLDASKNSTVGCEAFEN
                     SIVAYYSIEEFLEIMQNDFQLTKDIISYMERRIRRLYRQLKNSISIKVDKKLAAKLYR
                     LSREFGVCCGEWTLLNVNITVTYLADMLGCKRETVSRMIKVLQKEELIKIDNKGFYVK
                     ETELSRYFKNN"
     gene            complement(20543..21391)
                     /locus_tag="PC494_003815"
     CDS             complement(20543..21391)
                     /locus_tag="PC494_003815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HDF3914212.1"
                     /translation="MSILEQLESPTFKVTKSDKLLIAYIKENIDDVFYKPISQIAKES
                     NIGEATITRFVKKMNFNGLQDFKVTLAQEISTINKKNIINKNIQNDEPALDTAKKLLS
                     SNVTTLENTVEIINSKDVHDCARLIINAKKVYFIGIGYSGIIAQDSNYKFMRIGLNCV
                     SFDSSHTMIMMSSIMEEGDLIIAISHSGETEEIIKTVKLARANNAKIISITENKNSEL
                     KDISDVHLSYVSGETVLETGSISSKLAQFFIIDLVYTQVVKELSNEAIERKIKTTNAI
                     KLFKNE"
     gene            complement(21410..22297)
                     /locus_tag="PC494_003816"
     CDS             complement(21410..22297)
                     /locus_tag="PC494_003816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HDF3914213.1"
                     /translation="MKNYVCIDVGGTSIKYGFIREDGFIIDKSSLDTEAKEKGGEGIL
                     AKIKDIVKKYIEENEISGICISTAGMVDPVEGKILFALEELIPNYKGMQLKKEVEKEF
                     NIKCEVENDVNCAGLGEMWLGAGRGATSSICLTIGTGIGGCIIINNKLINGFSNSAGE
                     VGYMNVNGSSFQELASTSSLIKKVAKIKNLNENDLNGKIIFDLAKNNDEDCLKELDNM
                     IKSLAVGIANICYVINPEVVILGGGIMAQEKFLKPKIDKALKEVLIERVYKNTNIEFA
                     KRQNDAGMLGALYNFLNKI"
     gene            complement(22355..23158)
                     /locus_tag="PC494_003817"
     CDS             complement(22355..23158)
                     /locus_tag="PC494_003817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF3914214.1"
                     /translation="MENIDVFLLIGQSNARGLGNPKESIIPNENCFEYLSTDEIINMR
                     CELETSEGDGTIAPAFSNEWNKLTGNKVCFIHNAKDGSRIKNWNHDNNWFLNDTIEKF
                     NTGCTTLSKHYNIENKYVIWIQGESDAKYGSDVLYYKESLKKIAYRLKEECMIDKMFV
                     SLTGYWLGEDEYFIRTRRIAAAQESACSECDILCVGSKIAMQFHDRGLTIDDVHYTQE
                     GLNMLGEDLCKNIYKYHITKEKSVLSDTIDLSEARKYICELEKISKRFV"
     gene            complement(23318..23770)
                     /locus_tag="PC494_003818"
     CDS             complement(23318..23770)
                     /locus_tag="PC494_003818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HDF3914215.1"
                     /translation="MIFGNINHSKTYSTLHEDLLRCFEYAKDNSLIDYEKGTYTIDGD
                     DIFVNIVEYKTCEKEDRFWEAHKKYIDVHLMLDGCERIDINFIENLEQKIYEEKGDFL
                     PLDGKNNGYMELRKGDFLVCYPEDAHMTGIKVLEKENIKKAIFKVLVR"
     gene            complement(23900..25402)
                     /locus_tag="PC494_003819"
     CDS             complement(23900..25402)
                     /locus_tag="PC494_003819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003462875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:solute symporter"
                     /protein_id="HDF3914216.1"
                     /translation="MVGFTWIDFAILVVYLLAVLFAGLLFSKKEMKGKEFFKGDGTIP
                     WWVTSVSIFATLLSPISFLSLAGNSYGGTWILWFAQLGMFIAIPLTIKFFLPLYSRLE
                     IDTAYEYLEMRYESKGLRVLGALMFIIYQIGRMSIIMYLPSIVLAGLTGIPVNVLIIV
                     MGVIAIIYSYTGGLKAVLWTDFIQGMVLIVGVTGTLFYLIASINGGFGTVMDTLTTGH
                     KFLASNEVMFDKNILSTSAFIIFVGAGLNTFSSYVSSQDIVQRFTTTTDIKQLNKMTY
                     GNGVLSMGLATVFYLIGTCLFIYYTQNPDLAQTVQQDQVFASYIAYELPVGITGILLA
                     AIYAASQSTLSTGLNSVATSWTLDIQTIITKDISMEKQTKIAQYISLGVGILSIAVAI
                     VLANGEIKSAYEWFNSFMGLVLGVLAGIFVLGAFCKKATKMGAYVGFIVSAILVVYLK
                     YRMPEVTSWAYSLITITTSVVVGTIVSAIEAKVKAKVSLPKAETTVYYEK"
     gene            complement(25435..26301)
                     /locus_tag="PC494_003820"
     CDS             complement(25435..26301)
                     /locus_tag="PC494_003820"
                     /EC_number="4.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003452648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylneuraminate lyase"
                     /protein_id="HDF3914217.1"
                     /translation="MKGIYSALLVSFDKEGNINEKGLRQIIRHNIDVCKVDGLYVGGS
                     TGENFMLSTDEKKRIFEIAKDEVKEEIKLIAQVGSVNLKEAVELAKFTTDLGYDAISA
                     VTPFYYKFDFEEIKHYYNTIINSVDNRLIIYSIPFLTGVDMSLDQFGELFENEKIIGV
                     KFTAADFYLLERMRKTFPNKLIFAGFDEMMLPATVLGVDGAIGSTFNVNGVRARQIFE
                     LTKNEKISEALEVQHVTNDLITDILGNGLYQTIKLLLEEQGVEAGYCRQPMKEATDEM
                     KSRAKEIYRKYF"
     gene            complement(26386..27057)
                     /locus_tag="PC494_003821"
     CDS             complement(26386..27057)
                     /locus_tag="PC494_003821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HDF3914218.1"
                     /translation="MLDKVKGRLIVSCQALEDEPLHSPFIMGRMAKAAMEGGAVGIRA
                     QGVEDIIEIKKVTGLPVIGIIKRNYEDSDIYITPTKKEVDELLTTGCEMIALDATNRV
                     RPNNEDLKELIKYIKENGVLVMADISNYDEAIKAQEYGVDCVSTTLSGYTPYTKTLEG
                     PDFVLMERLVKDLEIPVIAEGKVNTPQDLKKVFELGVHSSVVGSAITRPQLITEKFVK
                     AIEIN"
     gene            complement(27330..27821)
                     /locus_tag="PC494_003822"
     CDS             complement(27330..27821)
                     /locus_tag="PC494_003822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HDF3914219.1"
                     /translation="MEGNTNNKVDDKFSKVKKKFGSGKFKVELYKEKSKLNREIDDIQ
                     EEKAKIFLEMGILTYQKIREDSINDNSFDKLCDELLELDKLIYEKNMEINEMEMAESN
                     VTCECGYVGNVNDKYCAECGKKFELENECDDFIICGYCESEIDTEAEFCPCCGRKIII
                     DLE"
     gene            complement(27843..29207)
                     /locus_tag="PC494_003823"
     CDS             complement(27843..29207)
                     /locus_tag="PC494_003823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HDF3914220.1"
                     /translation="MGEKKINNMNYSHNNYSKKTGEPTRKIKNSHITLKSKEEKICSS
                     CNKENNTKDNYCKFCGNELYEIASLRPLETKLDLKSKIKELSYHANKRGVFLTTFTTI
                     FILFIIALIFKAIITIQFNDISYLVNPAHIILALNLGQISVSMSTMMGSGFINANIGL
                     LILLIIPILVLLISNLIFMRKRCRDSKTVLANSLGVGIFYGLVLAILSIFTNVKTSSH
                     SMLEYGYALEYSYEFFSVLLNGFVLGFICTYITTYKKSYEKENMYLSLFSNSIRTFIL
                     GYVLVLVILLVLTISDSSYLNELDMSSYSNGLNLFTILPQIASYMWAFANGISVTIIN
                     STVSMFTLSSSSLFGDTKLMFYAMGALSMLILLLNGYKLRFKYNTDSIRPIIVFSIYY
                     AFLMGILALFSTFILDSNINFFNTTNYGTTLIMQFKVLQAIVISFVYSFVISLIGYKL
                     NSAD"
     gene            29626..30801
                     /locus_tag="PC494_003824"
     CDS             29626..30801
                     /locus_tag="PC494_003824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HDF3914221.1"
                     /translation="MNLEKIKKFFGFPLDKKHKDNVEKELCNYLYHTGKIICIIIVIS
                     QIIMMISISAREGGPFVTPRRQWYFYMYVTLFCVSSVFMFVFSYLWNKKKDCCTFYIN
                     LWIIYVTFFCLWGCVITLLDQLGGNDLSVFSYIMLAAAAFSVLKFGESVIVFGGCFLF
                     LNLFLPGIQTIPGNEFSNIVNTFFITSLAIFVSTMLYRNRVFTYYDKLLISQQYEEIS
                     HINNLLNDKVMTDDLTKMNNRRYLEDILQKKLISHANQEPITGMMIDIDYFKQFNDNY
                     GHQKGDYCLQNIAKVILDFTSSENEHAIRYGGEEFFICIFNCNEADAKLKSECLRKII
                     ESCNFERDDVPLKCVTVSIGVYTKKIGKTITLNEFISNCDKALYTAKEQGRNCVAFY"
     gene            complement(30974..32371)
                     /gene="asnS"
                     /locus_tag="PC494_003825"
     CDS             complement(30974..32371)
                     /gene="asnS"
                     /locus_tag="PC494_003825"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HDF3914222.1"
                     /translation="MQKEFITVKELYREKEQYIGKTVKVAGWIRTSRVSKNFGFIELN
                     DGSFFKNMQIVFDEKVENFKEVGKLAISSSILVEGELVSTEGAKQPVEIHAKSIVVEG
                     ESDSSYPLQKKRHTLEYLRTIAHLRPRSNTFSAVFRVRSIAAYAIHKFFQERNFVYAH
                     SPIITGSDCEGAGEMFRITTMDLNDIPKTEDGKIDYTQDFFGKEANLTVSGQLNAEIM
                     ALSFRNVYTFGPTFRAENSYTGRHASEFWMIEPEIVFADLEDNMELAEDMIKYVISYV
                     LENAPEEMEFFNSFIDKGLLERLNKIVNSEFIRITYTKAVELLIESGHEFEYPVEWGC
                     DLQTEHERYITEQIYNCPVFVTDYPKDIKAFYMRMNEDGKTVRAMDLLVPGVGEIVGG
                     SQREEREDVLLDRINEMGLREEDYWWYLELRKFGTATHSGFGLGFERIIMYMTGMSNI
                     RDVIPFPRTPKNAEF"
     misc_binding    complement(32448..32681)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(32850..33044)
                     /locus_tag="PC494_003826"
     CDS             complement(32850..33044)
                     /locus_tag="PC494_003826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3787 domain-containing protein"
                     /protein_id="HDF3914223.1"
                     /translation="MESKKARALKGKDNKRLKSSLLVGNESTAAWADVEKLKPHSKVS
                     IPSIKGVEEAKDWVDNGSKL"
     gene            complement(33317..34990)
                     /locus_tag="PC494_003827"
     CDS             complement(33317..34990)
                     /locus_tag="PC494_003827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family peptidase"
                     /protein_id="HDF3914224.1"
                     /translation="MEKSYCIIYQGDIESALQENGINRYMVLNSQLAVIYVPLDFDET
                     ILNNIIQVAWWEESEPMSSLIEITNNVNNGETITTAAETDYIYENPYNDITGRGILLA
                     VIDSGIDYLHPDFINDDGTSKVLYLWDQEANTNPPPEGFIFGSEFTRSELNIAINRND
                     GSLSQDNIGTGTLVSGILVGNGRINSQYRGITTESDLIVVKLKSYTDTYYAGRINYSV
                     SDFLAAITYVTNIARTENKPLIINLTIGVKSSAVATTSILDTFNILSSAGVVVVSGAG
                     NQGNTDIHYSGRFSSVGEVQDVIIQDGDDYALDITLNTNGPDKVGAQIISPSGEVSHD
                     IRYSPDFYIYRGKFNLENTTYAMRFIYPYITSGKENLEIRLRDIKPGVWILRLTSELI
                     INGEYDIYLPNKNLIAPDTRFLDPDSVATITMYAASDDVITVGTFNNKTDSMWIGSSK
                     GPIRGRGIKPDIVASGVDIISTYKNGTYNTGTGTGVSSSIVTGVLALLMEYLEKQDNV
                     PRLSLFTQVLKTYLILGATKLEIYTYPNVSQGYGILNLKNTIQQIANTL"
     gene            complement(35000..38398)
                     /locus_tag="PC494_003828"
     CDS             complement(35000..38398)
                     /locus_tag="PC494_003828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HDF3914225.1"
                     /translation="MIIINYELIVKYNGDILRLEEELGVSVEILNSSYAIITSSNEED
                     VNILLTYPEIEFIEKPFILQTQDVQSFSSTGITGFKNRTGLTGKGTIIGIIDSGIDYT
                     LPVFRDSDGRSKILYYWDQSIQGNPPEGFREGTLYTNEDINNAIDGSMYIPISTTSLH
                     GTHVAGICATIASDARIIVVRVGNIQTDIFSRSTEFMRAIKFILDRALELRMPVTLNI
                     SYGSNEGSHRGTSLFEQYIDDMCLFWKNNIVVAAGNNADKGGHKRIRLQNNITEEVEF
                     IVGEGERILNINIWPDFVDDFSVHLVNPSNNQTQAISLTSGEIRNTLGETRITGYFYP
                     IAPYSLTRRVTLQLSSNTQITPGLWKIVFEPIDIVTGNVNIYLPTSEGLNRNTRFLIP
                     TQELTVTVPGTASRVITVGSFNSRTDIVSIFSGEGDTQLGVFKPDLLAPGEDIVSFLP
                     GGTSGALTGTSMATPHVTGVCSLFMEWGIVNGNDLFLYSQKLRALLLKGARRLSNQSY
                     PNNSSGFGFLNLSDIDLYTLSNINQDLETEDIGYRSINKSFKDEENSYKFIDGYNMQI
                     HNDLENEIYISKNASRQSGILSGIDIVHTPEFEEELAGLGMSQRFFKISDSLGVLSIN
                     NTDYNSIQRVLQLPSIIRTVSTTKMTLLGEINRGTFGGVVATEEMGVNFFKNNPNINI
                     TGRGTLISIADTGIDYLHPDFIYPDGTSKIVYLWDQTKEGTPPDGFYIGTEYTREDIN
                     RAIAENDPSLSQDEVGQGTMLSGICAGLGNVNSEYAGIAEDSELIIIKLGKIDDFYNS
                     AMLFAASQYAYKKAFELGRPLVINMSLGTSSLAGLTNRSNSEKAFFTRGLCITAGAGN
                     EGNTQTHTSGIIPYVGGSVEVELELNEDEEELSLELWLNRPDKADVIIVSPTGEESKS
                     VGISNYNKVTGLFDLEGTEYSITYIYPTTFSGQQFTNVTLKNAKRGVWKIRLVGVYII
                     TGRYNLYLPNRELLKSGTRFREVDPFYTINYPAIQDDLITIGAYNTINGSLWQSSSRG
                     PTIEDRLKPDIVAPGVNIIAAYPGNTYATITGTAAASAHAAGAAAMYFQYTFVDGRYP
                     NQAYVQKIKTFMQAGARKDSNTVYPNTNSGYGLLDVRGMFDVLR"
     gene            complement(38566..39762)
                     /locus_tag="PC494_003829"
     CDS             complement(38566..39762)
                     /locus_tag="PC494_003829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VWA domain-containing protein"
                     /protein_id="HDF3914226.1"
                     /translation="MFIEFFYLLRSRGLNVSLNEWMTLIEALDKGLCYSNFSNFYYLC
                     RMILIKSESDFDKFDAVFLEYFKGIEHQEEIPEEIMNWLKKPDIDLEEFERLEQNPNI
                     NLDKLRAKLEERIKEQDSPHNGGNYWIGTGGTSELGHSGKGQTGIRIGGNSTYGRAVL
                     EVAGERKYRDFRDDEVLNMRQFQVALKRLRQFSTRIDAPKTELDLDKTIEETCNNAGY
                     LKLFFEKPRKNTVKLLLLMDSGGSMRGYSTLCNTLFQSVSKSNHFKDVKIYYFHNCIY
                     DRLFTTPECWLSKSINTEWILKNIDKNYKVIIVGDASMSPSELLHIGGNYRGPYNYTP
                     GIEWLKRFKRKYSKIVWMNPELRDGWDSINYWYQTQRMIQSEFNMFPLTVKGLEKALK
                     NLMVSR"
     gene            complement(39783..40604)
                     /locus_tag="PC494_003830"
     CDS             complement(39783..40604)
                     /locus_tag="PC494_003830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MoxR family ATPase"
                     /protein_id="HDF3914227.1"
                     /translation="MIKKEISNFRGSSDYVVSPELMASVNVAIALEKPLLIKGEPGTG
                     KTMLAQAISNELKKDLVIWNIKSTTKAQEGLYVYDTVQRLYDSQFGGEGVDDISKYIK
                     YGKLGEAFSSNQQVILLIDEIDKADLEFPNDLLWELDKMEFYINETKETVRAKQRPIV
                     IITSNAEKELPDAFLRRCIFHYIEFPDRDMMEEIVKVHFDKVEEHLLEQVMTTFYWIR
                     SLKDIQKKPSTSELIDWIQALTLSGMPIEKIEKEVPFAGILLKNNEDIESMQRHL"
BASE COUNT        13668 a         6861 c         4721 g        15456 t
ORIGIN      
        1 atatataaaa tagaaaattt ttttaatttt caaaatatat tctacatatc taatatgtaa
       61 ttacaataaa aaatgctata attaacatat tattaattcg ttttattatt gtagtatggc
      121 tatgaaatta tgaaaatatt tctctaatta aaaatatgat ttatccatat ttgtttattg
      181 tagatacaga ctatacaaaa ataaatagca cttatttcag tataaaaaca tatatagtct
      241 atatttagac taaaaaagta taaatagtct atataaaaca acttaaacta tgaatataat
      301 ctaaagtgga gggataataa ttggcaaata taggaaaaat aataggagat agaataaaag
      361 tctatagaac aaaattggga tatagtcaag agtttctagc agaaaaggca ggtttacatc
      421 caacatatat tggtcagatt gaaagagctg agacaaatac atctatcaat attataatga
      481 aaattgctac tgctttagac ataccacttg aattgttatt tgcaaatatt attacaacag
      541 aaggcgttga taactctgta cctttagaat gttatgaaat gattaataaa ttaactgaaa
      601 aagaacaaat tgcaatgcta gagttaataa agtgcatcat taaatacaaa gaaatataag
      661 tgagggaaat agtaacaata atgaattata taggtaaaag acttaaagaa gaacggaaaa
      721 aagcaaattt aacttcaaaa gaatttgcaa atatggttgg agtatcgcct tggtatataa
      781 ctcaaatcga aagtggtaaa aagaatccaa gtcttaaaac attcataaaa tttgtaaata
      841 tattaaatat ttctgcagat gttcttataa aagatattac ttccactgga aaaacatatt
      901 tagaaaatga tataaatgaa gagttaaaag acttaaattc aagagaacta aatctgatat
      961 cacagattat agacatcata aaaaagaata aaatataatt ctttatattt tatataaaaa
     1021 aaaaggttat ttgaaataaa taaccttttt ttgtcttttt gtgttaacat tgtcttatag
     1081 tgctaatgag tactattaga ccatgttcta tggccttatt ttaatataaa acgattggag
     1141 ataggctatg attgtgattg aaggtagcga taaatttaag attgcaaaag aatatattga
     1201 tgtagaatat actcttttta gcaaagtaac ttttaggtat gaaaagttga aatttaaaga
     1261 taatgctgaa ttggaaaaaa ttaagatgtt taaatataaa aatggctaca tccctaataa
     1321 attaaacctt tcttttggat atggattctc ttcttataaa aagcaaataa ttagagaaac
     1381 tgtagatact ttaagattga cagaaatttt ttcaagcgag aacatagaag atattaaatt
     1441 tataaaagat ggtacaaaaa aattagaaat tagcatagag aaagttgtga aatttaaacg
     1501 tcgaaaaaaa agaaattatg tttgttgcta ttgccctgat atgtataggg acataaaact
     1561 cgacaaagaa tctatcaata agatatacaa cagaaaaata aaaatagaaa gagaagttaa
     1621 tatttttgaa gatgaggatg ttataataaa caaaaaagta ttgaagtttc caaagtcttg
     1681 gacaaagaat atgcaaaaat attggttaag tgaaaataag tatcccatac attctactgt
     1741 aattgatgat gatagatata aatgttgtaa tgtacaatat acaaaaaata gagtgataat
     1801 attatattac atatataacc attaatatac ataattacaa aaaaataatg acaaatatac
     1861 ataatacaaa tatatcttct actttagata aaacagttat tatgaaaact tactatctat
     1921 aaataataga aatgctagta taccatctat aatctaatgt ctagtaggtt ttaatggcat
     1981 attttaaata tgccatagtt gatttataag attttctata tcactttcaa aatacacact
     2041 aaatagttgc ttttcagata taattgccca atttaaattt tactatctga aaagtttttt
     2101 atatttaatt tatatcttca aaaataaaat accttctaat atttctatat aattaattta
     2161 attaatactc ttatgtaata gattaagtac tgaatttaac tctttaaatg atatttgtcc
     2221 tggtgctgaa acactttttg cagctccaaa agtcaatgca gaaccaaata tttcaccaca
     2281 caatctactt ataacaccca ttcctgacat tgacattgtt attattggtc tatctgcata
     2341 aattttaaac atttcatttg tagcttcaag tagcactaac acatcttttt cattttgcgg
     2401 cataacagct attttgggta aatctgcgcc caattcctgc attctacata aacgagatac
     2461 aatctcttct ttttttggag ttttattaaa atcatgatta gatataatta ctttcacttc
     2521 ttttttatga gcaaaattaa ctacttcatc tatgacctca tctcccataa ataactctac
     2581 atctattaaa tctactaaac ctgtattaga aatttcttta ttcaaagtag tataataatc
     2641 tcttgatatt aatttttctc ccccttctac tacacttcta aatgtgaata ataaagggat
     2701 atcatgtata taacttctta attcatagag aacttcctta acttctttaa tattttctac
     2761 attctcaaaa aaatcaactc gccactctat aatatccaaa catgcatctt ttaactcttt
     2821 agcctctttt ataatatctt ttttattttt cccaataatt ggtacacaaa ttttaggtct
     2881 accttctcca atagtaatat tttttacttg aacttttctt ttcatattct cctccataat
     2941 cagaaattct ataggacttt aaattctatt ttctgcacaa tttaattata cattaaaaat
     3001 actatacatt ataaaaatac taatttaaaa ataattttta ttctaattct taaaacaatc
     3061 ccacatattt tagaaaaggt actctataat atacaaacac ttttttttac ctaaatttat
     3121 tttaacattc tataattttc acaatattct ttaaatttta ctcatataaa caatattatt
     3181 ctggatgcta atagaattaa tctataaatc atagtataat tatgcagaaa taactcgaat
     3241 ttcactactt atgaagagat tgaatattaa tgaatctaaa tcatttgcat tatttaagag
     3301 ttttgactaa agttgaacac catacaaaag tagctactca attgtttata ccccaaccaa
     3361 gcttaagtaa tgttatatag attctctaaa aagaatttag tatcttttta tttgaaaaac
     3421 ttatattaaa tttgattatc ttttcataag ttggtaaatg tcgatatatc ctgtatctac
     3481 aaggagtatc gacattttct ttttggaaga tactttgcat aagttggcat ttaaccgtat
     3541 aagaatgcca tcaaaagtag taaataagta gtaaactcta gtcatactac taggattata
     3601 accgttccat ttcagctctc gcagaactaa atgaaccatg tgcataatag ccaagcgtca
     3661 tagtaatgtt tttatgcccc ataatatatt gcaatatatt agtactcatt cctttgttag
     3721 ccatatttgt acagagtgta tgcctaaagg tatgtggcgt aatctttggt agcttgtcct
     3781 catgggtctt gttatacttc ttgactaacg ctcttaacat gctttgataa tgagttgctt
     3841 gttttggtaa tccatcttgt ttaagaaata ggaagttctg gtaaccatca acaatgattg
     3901 gttctgcttt agcgttctta cgccgttcaa cgatacgttc aaatgattga taagctcttt
     3961 cagtcattgg aatttctcgc ttaccctgtg tggtctttgg aacttctaca taatagccaa
     4021 tcttagtatc actcaacaat tgatggtcta ccataatggc tttatttttc atatctaatt
     4081 ctaaagtcaa accgcataat tcagaaatgc gtagtcctgt ttctaagagg ataacaacat
     4141 catcataata tttataataa gtcttatcgc tccccataaa ggataataag cccatttcct
     4201 gttctggtgt tagagcgatt tttggttctg ttgtatcttc caaaacatca cttaactaaa
     4261 aattaaatgg attctttcta atacagtcgt cttgaattgc catgaaaaac gacgctttca
     4321 gtgagcgctt ataattgtca atggatttat aagcacaccc atcttcactc attcggatag
     4381 cccagctttt agcgtctgat aatttaacca tatcaatgct ttttgcacct agtgggtcat
     4441 tgatagtatc tatattttga tttataattt atacattttt ttaaaaagag acttttaact
     4501 gtaaagaatc tatgtataaa cttagctatg ttgtccgtgt atctacaaag gatcttgacg
     4561 agctaaaaag gcgttgtgat gaagtcaaag acttttacga cgacttatca atcaagctcg
     4621 tgcgtccctt tggggatatg ttgggattgc atggcgaatt tattcctgtc agcaaacgtt
     4681 acatcaatga ttatattcaa tatgtcactt cggatttttt ggctggactt ggttttggag
     4741 cgacacaaac ccttggcgaa catgaggata tctatcttgg ctacaatctg gacactggaa
     4801 agaatgtcta tctaaaacct gcccttgcta gtcaaggggt aaagggttct attaccaatg
     4861 cgttagcgtc tgcgtttatc ggttcattgg gtggtggtaa attattcagt aacaatatgc
     4921 ttgtttacta tgcggtacta ttcggcggac aagcggtcat agttgaccct aaagcaaaac
     4981 gcggcaaatg gaaagaaacg ctaccagaaa tagcccatga gataaacatt gtcaatttaa
     5041 ccagtgatga tgaaaacaaa ggattgcttg accattacgt cattttgagc cgtaaaaagg
     5101 attctgaaag tttagcgatt gatatcctaa cattccttac tggtatctcc agtcgtgaca
     5161 gtgataagtt tttgcagaaa aatgacaact ggaaaataat aatggaatag tttctatgta
     5221 aatatatttt tactatctta cctaactaat tgaaagatga tataatttaa tcaaagattt
     5281 ggtaaggaga gatgaatatg catttaattg attttatgaa tgaagatatt aaaaagaagc
     5341 ttgttaaaaa aacgtataaa aagaaagaga ctattctttt tgctgagcaa gaaaatgaat
     5401 atgtaattct tatgattgac ggtattgcag aagcattcat cttaaatgtg aaaggaaaca
     5461 tctcaactat tcatctttat agaagtggta gtttttttgg agaaatggaa caatttaatg
     5521 atgggaaaaa acccgttgaa attgtcgctt tcacagattg taatgtatat aaacttcata
     5581 gagatgattt tttaaactgg ttaaggggag attttgaagc tacaaaattt ctgattcgag
     5641 aaatatctag taaattagtt gtaaatgctg aattaattga agaattatca tctttaagtg
     5701 ttaaagaacg acttctgagg tgtatatcct tacactatta tagaagtgaa ttaaatctgc
     5761 ttaccaaaaa acagcttgct agcgaagtaa acgctccgat tagaagcatt aatcgtgcta
     5821 taaatgaatg tgtacaagaa catctaattg cttatgaaaa caaaagattc agtgtaatta
     5881 atcagcgaga ggtattaaag aatcttccta caacataagt ataatttcaa aaaagtattg
     5941 gataataatt attcaatact tttttatttc gggtcaagtg acctattttt ttttatttct
     6001 tcattatata atactcctat gcataattat gttggattga tagctaataa aagacagtga
     6061 gaggtgttat attatgacta aaacacaaca ggaaatgata caaaacgtat tagaattttc
     6121 aaaaagagat agtaggataa taggacttgc aattagcggt tcttatatca caaaatcgtt
     6181 agatgaatat tctgatttgg attttctgat tgtagcagat gataaatcct atgaagaagt
     6241 tatcgaagag agattactta ttgtggaaca gtttggaaca ttagtttctg cttttactgg
     6301 cgaacatgtt ggagaacctc gattgataat ttccctctat gattcccctg ttcttcatgt
     6361 tgattttaag tttacaacct tagatggttt actagatagg gttgaagatt cagctattct
     6421 ctatgaagaa aacaactgca taacagaaat ttattctaaa aaagaagcat acttcccaac
     6481 tccagactta cagtggattg aagatagatt ttggatttgg gttcattaca cttgcactaa
     6541 gattggacgt agagaactat ttgaaacaat tgatttttta tcttttttaa gacaatcagt
     6601 acttgcctcg ttaatacagc ttctcttagg taaattacct cgtggagtta gaaaaattga
     6661 attggacgca ccccaatata ttgaagcatt agaaaagacg gttgctaacc atgaatataa
     6721 aagctgtgtt aatgcattgc aggctactat caacctgtat cttgaattaa gagaggaatt
     6781 atcacaaagt cctattgtcc gaaaggttga agctgaaagg gttgcattac agtattttca
     6841 agatttaatc aaataaaccc aaagtaaaaa aatattgaat agtaaatatt cagtgttttt
     6901 tcatttttgg tcaaatgacc tagattagtt gttgtaacaa ttctataatt attttgaaag
     6961 taacagtatg gaggataact atgagtgata ttttaagtag aattacaaat aaaattgggg
     7021 ataagaatat agttgataag ttatcagctc tatcaaaatc agatttgaac tcacttctat
     7081 tagaagtgtt tgatagacaa gcaaatactt taactgcaac tgatattcta aagtcatacc
     7141 aactaaatag atttactatc cctagcggta tagatccaga agaaattcat gctttggagt
     7201 caaaattatt gagaaaagca ttcaatatgg atatcaagac gattatgctt tctccctctg
     7261 ctccattagg tagctgtagc gtttttggct ccgtagatca atataatgta gtaagtgctc
     7321 tacgagggac agaaacactt gcagacccct caaatatgtt ggcaataatt attgctgata
     7381 aattaaaaag aaaagaagaa aataatacca tacctatcca catggctact actgctaggg
     7441 taataagagc acaaaatttt gtaggtaaag gtttatattc acattttggc ttatattgta
     7501 tggtttcatc tggtatagat acagggtctt acacttgtga aaaaatgttg ttagaaaagc
     7561 acttaaacta ttataaagat atattaagtg aaatagaaaa tgttcgtttc tctattattc
     7621 tacgcaaaag aaacggatac aaagataatg acggattttt cgacagaatg gttgaaacta
     7681 tcaaacttat ttttcctaat atagagttat caattcataa tgatgatgtt gataataatt
     7741 attataaagg tatcaatttc aaattatcgg tcaaacaagg aaatgaaacc gttgaaatag
     7801 ttgacggtgg atttgttgac tggacttatc aaatgcttgg aaataaaaaa gaacgctgtt
     7861 tgataagtgg tattggctta gaaagatttc ttgtagctgt ttcataaaag gagaagaaaa
     7921 atggaactta tagagtggaa ttatgcttat attaccgatt tagttgagtt tgcgaatgat
     7981 aaagaaattg caaacaatct tcgtgacaac ttcccccacc cttataggta gcaaaacgct
     8041 agagatttta ttagtttttg tttgacaact tcagatgtta aacaacttag ctatgctatt
     8101 ttttatcaag aaagggctat tggaagtatc agcctaacat ttgaagaaga tacctctatt
     8161 aataaaaatg ctgaattagg ttactgactt gctaggaact attggggcaa agggatagca
     8221 acaaatgcag taaaagaaat atgcaaaatt gcctttgaaa aatacaacct taacaaaatt
     8281 catgctaatg tatattccta caatagagag tcaagtaaaa tgtggcttta agattgaaga
     8341 atactgtcac aattcataat aaagaataga aacatgattg attgccatgt atatagttta
     8401 attcgaccgc aatagcattt attagaatta acctactttt taataacaga ataagttttt
     8461 cccctctatt aatttcttat gcatctttgt atttttatga aaagctagcc aatgcatatt
     8521 tccatacatc aatatggtgg tggcttacaa ccaatataaa ttaaatacgt tttaaagaat
     8581 acacattttt gccctatagg cagagtgtgt atttttttct cttttttttt gaaatttatc
     8641 gaagatttaa cgccctccca ccgtgatagg agtaagcaag gttatttaac tccttgcgat
     8701 ggaaagaggg tgaaatctta tggttgatga aaagacaatt gaacatcaat tcgacagttt
     8761 ctgtaaaaca gttttgcgta actatgctag agatatttat gacgaaaata aacgcagaaa
     8821 tgattatttg gtatctctcg aatctttgtc acttgcagaa ttaagtaaat tgagtatttt
     8881 agatgattat gattctaact acatctgtat ggtttcttac gactacaaca tacgaattga
     8941 agatgtatta atggcacaag caatcggaaa acttacaaaa agaaaacaag atataattct
     9001 actttcattc tttctcaaca tgacaaatgc tgacatagca acattgatgg atttagcaga
     9061 aaataccata cattatcaca aaacaaatgc actaaaagag ttgaaagaac tcatgcagga
     9121 acattgaaat gaaacctact aaagaagtat taccttttac aattatttta cttgctgtac
     9181 atggcgatgt aaatgcaata aacgtaatac ttaaacattt tgaacactat atcattcgtc
     9241 tttcacagaa aactttattt gatgaatacg gaaatcccta tattcatgta gaagaagaaa
     9301 caaagcgaat gctaggaaca aaactaatca ctgctatttt gagatttaat ttgtcttaat
     9361 ctcgccctct ctccatgtat caagctattt ggtacatgga gaatcactaa ttatttgtct
     9421 ataaaagccc ataagctatt gtgatttttt ataggcaaat caatgccgac tgttctttga
     9481 caactgaata aagtagatag atacgtttgt gatacagata gccaacaaat actatacgcc
     9541 atgaccttaa tcaagagagc tactatatag tgatttgtga ataacctttg gaacggttgt
     9601 tttgccgtaa cctgtaccac agtataatga tacacctgta tgacacggtt ctgcccataa
     9661 gaatgggatt ggttgaaata ccaatggagc ttaccaaagc catctatcta cttctgaact
     9721 acgaacatag aaaggagtga tacattctat gaacaatact gatgtaccta tttgggaaaa
     9781 atataccttg acgattgaat aagcgtcaaa atactttcgt attggagaga aaaaattacg
     9841 taaacttgct gatgaaaacc ttgattctgg ctgggtcatt atgaatagca atcgcattca
     9901 aataaagaga aaacaatttg agaaaatcgt tgatacactt gacgttatct aatgaaattg
     9961 agccttatat gttataatat tcatatgacg tatcaagctc aattcggtta ttgagaggag
    10021 cttcttatca tgtcaactga aaaaagacga gataataaag atagaatttt aagaactgga
    10081 gagagccaga gaaaagatgg aagatacgca tataagtatg tatattcatt tggtaaagca
    10141 caatttgttt actcttggaa acttgtacct actgataaac ccccaaaggg aaaacgtgat
    10201 gatatatcat taagggataa ggaaaaagca atacaaaatg accttgatga tagcattgac
    10261 actattggta agaaaatgac agtttgtcag ttatacgcta aaaagaatgt actaagaaag
    10321 aatatccgac ttaacactaa aaaaggacgc cattatctta tgaagattct taacaaggag
    10381 tgattctgtg aagagatgta ttgtagtagt ggaatagtca aaaacataat atatattaaa
    10441 ggagagattt aaatatgact attccaagtt caaataaggt atatccaaga agtaatgatt
    10501 atcaaactgt atatcttaaa aatgtaataa caagggaaaa tatagaagtt ggagattaca
    10561 caatatataa tgacttttat aatgacccaa gagattttga gaaaaacaat gtattgtatc
    10621 attaccctat aaacaatgat aaattaataa ttggtaagtt ttgctcaata gcatgtaatg
    10681 caaaatttct aatgactagt ggaaatcact caatgaaatc aaaatccaca tatacttttc
    10741 ccatctttta tgaagaatgg aaactcgata tcaaccatat aacggacgct tgggacaata
    10801 agggtaacat tataattgga aatgatgtgt ggataggtta tgattctata attatgtcag
    10861 gtgtaaatat tggtgatggt gcaattattg gaacaagagc agtagttact aatgacgttc
    10921 caccgtattc tattgttgga ggagtacctg caaaaattat aaaaaagaga tttaataatg
    10981 atacaatttc aaaattatta gaaattaaat ggtgggattg gccatataaa aaaattcaat
    11041 caaacattaa gcatattcaa tcaggaaata ttgataaatt agtttaatat tttataattt
    11101 atttatatta aactttactt taataatcat tttataagag ctttttcaaa atttgtatat
    11161 tattttaata tatataaatt taatacaaca ttaaataaaa taaaaagtaa agttacttaa
    11221 taaaaagtta ctttactttt tattatttaa attcctgttt ttattataat aggtaaaatt
    11281 ctattaaact agttcacatt ttcattatta ttgatatatt atatatgaat ataccatttt
    11341 gttttttaat aaaaaaatca tgctacatca atagtaagca actattaatg tagcatgatt
    11401 ttttgtatct aaataatctt agtatttacc tatcaatata gattgatata tcaaaaacta
    11461 tagtcttcta tattcttctc tttttagctt ttggttactt agatagtaat caatttcatc
    11521 aattagacgt tgtttatcat caggtaatac accttttaaa ttagcataat ttgatgcatg
    11581 attacttcta aatacaattt tttcattagc atctatattc tttatcatct ctttaatttc
    11641 ttgtaacaca gccttatcct ctagtattgt aaactctcct gccttaagta aatcgtaaag
    11701 ttcagtatta ggttctacca ttaaactaag tacacccaca taatctggtg aaattgctcc
    11761 taacattttt cctgtatcaa ctgcatgctg atgtgttttt ttagttcctc caagacctgc
    11821 tattacagtg gctgataatt taatcccact ttttttaact tttctaccaa cttttattaa
    11881 ttgttcacta ctaaaacctt tcttaatatc ttctaatact tcattgcttc cactttcaag
    11941 ccctagataa atcattttaa caccaagttt tcttaattct ttaagttcat catcagattt
    12001 tttctctata gatttaggag agccgtacat agtaattctt tcacactctg gaaaaacttc
    12061 ttttatatat aaaataatat ctcttaattt ctccattggt attatcaatg catctccatc
    12121 tgctaagaat attctttcta catgcttata atatcttcta aatatatcaa tttcattttt
    12181 tattacttct agtggcttta ttttaaattt tttagatttg tacatactac aaaacgtaca
    12241 tttgttatga gaacatccta gtgtgacttg tattataaga ctataagcct cacttggtgg
    12301 tctgtaaagt ggcatatcgt attccatatt aaaatccccc ttgtaataaa atattcattc
    12361 tattatatta ttaatattta ctttaaataa taacttataa aattatattt tttaaatttt
    12421 agtttaagat atattcttta aaaatttaat gatactattg gcagtaatat taagttgttt
    12481 ttcttgactt ataatagcat cattatctcc cttttgtttt ccataatctc caaattgtgc
    12541 atgatttcct ccttcaatct caacataagt tgtatcatca ggaagttttt gttttgattc
    12601 tacaagactt ttaaaattga ctactccatc tttgctcccc catatagata taactttttt
    12661 tcctaattct ttcaactcat cacccattgg ataagaagct aaaaatacaa cgccttcaat
    12721 taatttatta tcacgtgcaa aatttgatgc tgcaactcct cctaatgaat gacctcctat
    12781 tacccaatgt tctatgttgt tgtaagaatc cataactttc tgtgccttat tagttccaag
    12841 tatagctaga ttaagtggca tctttacgat tacaacctca tatccacttt ctgctatttt
    12901 tcttgcaagt ggagcataag attctatttc tactttagct cctggataca aaattaaacc
    12961 tttagaaact tttcttcctt ttggtgtaaa tgaaatgttt tcatttacag ttacttcaac
    13021 tttactattg ctgactagag cttcttttgc cagcttttga ggttcatatg ttttatttat
    13081 ccatatgaaa aagccaagca aaatcaatac aaatagtata cctattccct taaatatctt
    13141 attctttatg ttaaattttc tattattatt tttatcatct ttgttctcaa cctcatcata
    13201 aagtaaaggt ctctcaagtt ccatagttat actaaatgta tcatatttct tattacgctt
    13261 tacctttaca tctttactca taaatctaac ccccataata tttgaatact attatagttt
    13321 atcctaagta aattgttttt tcaaccaatg aaaaaaatca atattttaac tattttcata
    13381 taaaattcat aaatatatgt ttttgttttt tatatattat tttcttttag tattttataa
    13441 aacaaatagc catatacttt attttaaata tatggctatt ctataattta atatctaagc
    13501 tgcttctttt attgaaactt tagttatatt acttattcta tacatttctt tgacaccatt
    13561 tagagtttgc agtaagttta gacatattat cttgtcacct agacttttag tatttacaat
    13621 actctctaaa attacacttc ttccttcatc atacttatct acattgtaat ttgaaatata
    13681 attggtatct ctcaatattt tttcaacatc ttcatctttt attttatttt tattaacatt
    13741 tatatataga ttatacatat tacttattag taatttctga ttttctaaaa aatcctcttg
    13801 atgtttatct ttatatatag catttatcaa cataagtcta tcttcaataa gtgatggtat
    13861 caataataaa ttttttatat agtaaacatc agctacattt tctatagact tattgacttc
    13921 atcaattata tttttaacta ttcctttata catttctata acatgttgat agcctgtttt
    13981 agcatcatat ggtaatataa acttatttac tattaatgca ataattgctc ctaatgctac
    14041 atatgaaatc ctgcttattg ttaaaacatt tgggtctccc ataactactg ctgaaccaag
    14101 agctgaaaca gttacacata ccattaattt tctataatca actacataag agtttatata
    14161 ccctgctaaa agaactatta acgaccttaa tgtactatct tttattattg aaaataatac
    14221 aataaatatt acagctccta taaatgtacc ttctattctt tttctagacc tttgtataca
    14281 attttctgcg taaggttgtg ttaatgaaaa gacagttaac attatccatc ttccatctct
    14341 taaatggaaa taatccataa taaaacccgc tacagctgta gctaaagcaa tctttactgc
    14401 ataagaaaat cttatagaat ttaaattaaa gtttttctta tatattgata gtcgtttaaa
    14461 ttcatgaggt atctttgatt ttctttcagc tttcttttcg tctcttgatt ttactttttt
    14521 ataatctact aaaaactcat ataaattttc taaaacacta taaatttctt ttaaatttat
    14581 atttttagta tcctgagaaa taacataatc tctaaatcct aatatctctt tatcagttat
    14641 ggtatcttta ttttctaaac acatcttaat atagtttatt tctttcgttg ctacaactaa
    14701 aacatctgat ttactattta tgctactttc ttctaaaata ttttttatat cttcatcttc
    14761 aaattcttta ctatcctttt tgtatctttc caggattaaa cttattcttt ctaatgaaaa
    14821 taaaatattc attatgtcta tacctctaat actgatataa aagtcatctt ttctattatc
    14881 aaaaataacc attttcaaat ttttagatat agaatttatt ctataattac agctatctat
    14941 ttttctcata ctagatttaa ttatagaact atcatcatta atagtatttt ttaaaagact
    15001 aattttttct aataattcat cacatataga tatcagttct ttatctccga catttttcat
    15061 cctatttcta ttcataacaa attgagcaat cattattata actgctccaa cagctaaagc
    15121 cgacaatctc ataggaaatt cactttttcc tacaggtata cttaccataa atatatacat
    15181 tagaccaaag ggtacatata ctgctctttt taagtcataa ctaaatacat accctattat
    15241 aaataatgct ataaaattta ataaaactcc taaatacata ttttgtactg caaaaaatga
    15301 tagtattcct aagattatat ttattgctaa atacttcagt aaatttttaa ttggagaaat
    15361 agttaaatct ctttccaaga gtgttagcat agctgttact atacctacac ctataagtgt
    15421 atttttactt ccaaataaat atataaatat agaaataaat gctattataa aaataaacaa
    15481 ctttgttttt gatattacta gtttctttgt catcatatcc cccctaaaaa tttcaacaag
    15541 accaatttta tcatatttgt tatcttattc aaaatgcgct tttttacggt aggactttaa
    15601 ctttttttat atttagaact atataattca tatataaacg tattttttat atatataacc
    15661 gatatatttt cgtatgctcc catatttttt ttgtttcaaa tattttttca aaaatataaa
    15721 aataactctc tcaacaatac taaaaatgta tttatcaaga gagttataat ttatacaata
    15781 aatttaatta agcttttctt tacctaatat ataagttcca agacccataa ataaagctcc
    15841 tccaacaata tttccaagtg ttacagctac taaattataa atagctcctc caatagtaac
    15901 tgtacttatt gttggtgaaa ataatgaaac actataaatt gtcatatttg ctacactatg
    15961 ctcaaaacct gatgttataa aagcaaataa acataagaat atcataatta tttttgcagt
    16021 atcactatta gttctaaacg aacacaacac tgatacacat actagaatat tacataaaat
    16081 ccctctaaag aaaagagctg taaatggcat ggatgcttta ctagctgctg tatttgcaaa
    16141 aaattcagct acaggtcctt tgtctactag accagttcct acaaatataa tgcctaaaac
    16201 caaagctccg attaaattac ctacccaact gtatgcccat attttagaag tatcttttat
    16261 acttacacct ttatttaaca taccagcaga cataaccata ttgtttccag taaataactc
    16321 tgttcccgtc attataacca aacttagtgc tattgcaaat gataacccca ttactatctt
    16381 agtcataggt gaacctgcat cagtcaaaag tcctccaata gtaaatatca aaagtatacc
    16441 tatacctaca taaagtcctg caaacgcaga agataccaaa tattttactt tacttgtgtt
    16501 taataaattt atcttattta tagctgcatt agttaattta tccaaagttt ctttatgcat
    16561 aactccctct tccttctatt aaattttaat ttattcaaat atatgtttta ctcaatttat
    16621 agatatttaa ttccactcca gtatatgttt tcgtacattt tagttatttc tggaagctct
    16681 acaccttcaa gtgcccattt tttaaattcc ataaatcctg ttctatcaat tatatatcct
    16741 atatgttctt ttcctcctgg tgcatcttta tctatatact tttctacata tctataagta
    16801 ttaagtatta tctttattat gctgtcctca tctacccata aaagaaaatc ttctgctagt
    16861 ctagggtttt tctttcctgt tctacccatt atagctaatc tatagtattt tttctcatct
    16921 ctagtccatg catttgttgg gcaatttagt acacactctc cacagcctat acacttatct
    16981 ttatctctta ccaccttatt attttctgtt tttaatgctc caacagatat cttagaacat
    17041 ttttttacac atgctccaca atttacacat ctatcctttt catatattgg taaagccata
    17101 ccaataattc caaagtcatt cattctagct tttatacaat catttggaca accagttaaa
    17161 gccactttaa aatgtaaatc atttggaaat atagcttttt ctattctttt agcaaattca
    17221 gttgtattat attgagcctt tggacagact ttatttccta tacaagctgc tatatttctt
    17281 gtacctgctg ctggataacc tgcgtttttc tcactttgat ttatattcat tttttcaata
    17341 acaggttgta taattttatt tatttcttcc atatcttcca tatttattcc taatatttca
    17401 aacccctgtc ttgtagttat gtgcacctgt ccattgccgt actcacttgc aattttagaa
    17461 actacagcta aactctcagg gtcaataaga cctccaggta ctctaactct taaagaagtc
    17521 tcatattttg tttttgtaat tctataagca tttttcatta cttttttggt atttaaatct
    17581 cttatcacaa acttcacccc ctaatcaata agatttttag catatgaata atcaaatact
    17641 ggtccatcta aacatatgta agtatcatcc attttacaat gtccacattt acctattcca
    17701 caacacattt ttctttcata agaaacccaa atgttctttt catctaaatc tctttttaaa
    17761 aattcttcta ctgtaaattt catcatcatt ggaggtccaa ctacaactat agaagtattg
    17821 tttatatctt tcatatccaa ttctggtatg tattttgtta ctaatcctac attaccacta
    17881 tatccttcct ctgctccatc tacagtaact aaaatatcaa gttttttact ccatctcttt
    17941 aaatcatctg caaataaaat atcttttggt gatttaaatc ctactattaa tttaaacttt
    18001 tcgcattttt ctttattatt ataaaaatat tcaactattc ctcttacagg ggctaatgca
    18061 cttcctcctg ccactactac aatttctctt ccttcataaa gggatacatc aaatccattt
    18121 ccataaggac ctcttataaa aaaagaatct ccttctttat aattaaacaa ctcgctagtt
    18181 acttttccta catttcttat tgtaaagtca atataatcct ctccatatcc tgatactgat
    18241 attggacttt caccgtattt aggtatagat atctcataaa actttccagg caatacacct
    18301 tttgtattgc agtttactct aaaagtccat tctttatcag tatgtttaac tatatctagt
    18361 atttttgcac ttactggtat atatgggttc atttatactt cctccttact aattactaaa
    18421 tcatttattt tttctataca ctttgaaaat gatatgtatt gcggacaggc atcatcacat
    18481 cttccacaac caacacacat atgatatccg aatctttttt taaaatcatg tattttatgc
    18541 atagttttaa atctcattct ttcaccttgt ttttttctaa aagaatttcc acctgctata
    18601 tctgtatatc catctacttg acaagaagcc caaacccttc ttctctcacc tacattttcg
    18661 ttttccttat agaaaatatc ctgcattgta aaacatgaac atgttggaca tacaaaatta
    18721 catctaccac atcctataca tcttgtatca tattcatccc atattgaatt tcctatcatt
    18781 tcatttgaat caatattctc tggcacatct acagatatta aattatcagt tacataatca
    18841 acattaaatt cagttgcttc tccattaaat acttcaaatt cactatcctt tatatctaag
    18901 tacagtgtat ctccttctat atttaatcca attgaataat tatcagtttt gttagaatcc
    18961 atgctcacac aaaaacagtt tctaaaactt tccttacacc ctacaagtgc aaactttact
    19021 ttatctctga tatttttata aaaataatct ttttcttcac cattatttag atatatttca
    19081 tcaagtcttt ttataccatt tatgtcacaa gctcttaaga aaattaaaat tttcttgttg
    19141 tctaaatcgc tttccttaaa ctctttttca gtaaaataaa acaatacttg atttatggga
    19201 agtacaactt cttttggtga aaagtttgct ttcttagcaa attccatttc ttcaaaagcg
    19261 tttacctcct tgtatcttat aacatcagta tctgaaaaag tacctttaaa tgggattaaa
    19321 actggtgcaa atatcttgta gtcttttttt agataattca gaccttcatt gaacttagat
    19381 gaatctaatt ttagtttcat ttttatcacc tttcttatat tttagtttta cttacttgct
    19441 atcttgttta aatcttaaca ctttattttc tatgcttccg tgataattat cacagtttca
    19501 aaaataataa aaaaaatatt aatggagttt attaagttct gttaatattt ttttattatc
    19561 tacattattc aatttcaaat ctaatcactt aaatacaatc attaagtaca ataaaactac
    19621 tatctactca attttttgaa taaaaaagaa tcttatttgt ttttttatac aattcaatag
    19681 ggtaaaataa aaattaataa attagacaat aaaaaagaat ctataaatag attctcttaa
    19741 taatattttt atttaattaa aattctaata atactcttac ttaatcataa ttaattattt
    19801 ttaaaatacc ttgataattc agtttcttta acataaaaac ctttattgtc aattttaata
    19861 agttcttctt tttgcaatac ctttatcatt ctggaaacag tctccctttt acagccaagc
    19921 atatcagcta aatatgtaac tgtaatattt acatttagta aagtccattc tccacagcaa
    19981 actccaaatt ctctacttaa cctatataat tttgctgcaa gttttttatc tacttttatg
    20041 gatatagaat ttttcaactg tctatataaa cgtcttattc ttctttccat ataagaaata
    20101 atatcctttg taagttgaaa atcattttgc ataatttcta aaaattcttc aatactataa
    20161 taagctacaa ttgaattttc aaatgcttca cagccaacag tagagttttt agaagcgtca
    20221 agtgtaatat catttatgac ttccccacta tttaatatga aaattacttt tctctctcca
    20281 ttttcactta tcttaaaaat agataccttt ccttctaaaa gtatataaac actgtctaag
    20341 ctatcttttt cataaaataa aatttctttt ttttgtaatc tttttagttt aactttttct
    20401 ttaagttgat tcttcgtttt agtacttaaa ttattaaaaa ttattacttt atcaatatta
    20461 taatctttta atttagacat gtaatatctc tccattccta aatttttaag agagctctat
    20521 aaaacattac aaatttctta ttttattcat ttttaaacaa ttttatagca tttgtagttt
    20581 taattttcct ttcaatagct tcattagaaa gttcttttac tacctgtgta tatactaaat
    20641 caataatgaa aaattgtgct aatttagaag atattgaacc ggtttccagt actgtttctc
    20701 ccgatacata agataagtgt acatctgaaa tatcctttaa ttcagaattt ttattttcag
    20761 taattgatat aattttagca ttattggctc ttgcaagctt tacagttttt ataatctctt
    20821 ctgtttcacc agaatgtgaa attgcaatta ttaaatctcc ttcttccatt atggaagaca
    20881 tcattatcat tgtatgacta ctgtcaaaac ttacacaatt aagacctatt ctcataaatt
    20941 tatagtttga atcctgtgct attataccag aatatccaat acctatgaag taaactttct
    21001 ttgcatttat tataagcctt gcgcagtcat gtacatcctt actattgatt atctctactg
    21061 tgttctctaa agtggttaca tttgaactta aaagtttttt tgctgtatcc aaagctggct
    21121 catcattttg tatattttta tttataatat tttttttatt gatagttgat atttcttgtg
    21181 ctaaagtaac tttaaaatcc tgtaatccat taaaattcat tttttttaca aacctagtta
    21241 tagttgcttc accaatattg ctctctttag ctatttgtga tattggttta taaaatacat
    21301 catctatatt ttcttttata taagctatta ataatttatc tgattttgtg actttaaaag
    21361 ttggtgattc caattgttct aaaatactca ttaaaaaccc ttctattctt tatattttgt
    21421 ttaaaaaatt atataatgct ccaagcattc ctgcatcatt ttgtctcttt gcaaattcta
    21481 tattagtgtt tttgtaaact ctctctataa gaacctcctt taatgctttg tctatttttg
    21541 gttttaggaa cttttcttgt gccataatcc caccacctaa aattaccact tctggattta
    21601 ttacataaca tatatttgcg attccaactg ctaatgattt tatcatatta tcgagttctt
    21661 ttaaacaatc ttcatcatta ttctttgcta aatcaaaaat tatttttcca tttaagtcat
    21721 tttcattcaa attttttatt tttgctactt ttttaattag actgctagta gatgccaatt
    21781 cttgaaaaga acttccattt acattcatat atcctacttc accagcacta ttactaaacc
    21841 catttatcag tttattattt attataatac atccaccaat tccagtacct attgttaaac
    21901 atatagaaga tgttgcacct ctacctgctc caagccacat ttcaccaagt ccagcacaat
    21961 taacatcatt ttcaacttca cattttatat taaactcttt ttctacttct ttttttaatt
    22021 gcatgccctt atagtttgga attaattctt ctaatgcaaa tagtatttta ccttcaactg
    22081 ggtcaaccat acctgcagtt gatatacata taccacttat ttcattttcc tctatatatt
    22141 tttttactat atcttttatt ttggctaata ttccttctcc acctttttcc tttgcttcag
    22201 tatcaagact tgatttatca attataaatc catcttctct aataaaacca tattttattg
    22261 aagtacctcc aacatctata caaacgtaat ttttcataac atatctccat acaaattatt
    22321 tttataaatt aacaactcta tttaaaattt tatattacac aaatctttta cttatctttt
    22381 ccaattcaca gatatatttc cttgcttctg ataagtctat agtatcactt aatacacttt
    22441 tttctttggt tatatgatac ttataaatat ttttacataa gtcctctcct aacatattaa
    22501 gaccttcttg agtgtaatga acatcatcaa tagttaatcc tctgtcatga aactgcatag
    22561 caattttgct tcctacacat aatatatcac attcactaca agccgactcc tgtgctgctg
    22621 caattcgtct tgttctaata aaatattcat cttctccaag ccaataacca gttaaactta
    22681 caaacatttt atcaatcata cattcttctt taagcctata cgcaattttt tttagacttt
    22741 ctttatagta caatacatca ctaccatatt ttgcatcact ttcaccttga atccaaataa
    22801 cgtatttatt ttctatatta taatgtttac ttaaggtagt acagcctgta ttaaattttt
    22861 ctatagtgtc atttagaaac cagttattat catgattcca gttttttatt cttgaaccat
    22921 cttttgcatt gtgaataaaa caaactttat ttccagtaag cttattccat tcatttgaaa
    22981 atgcaggtgc tatagtacca tcaccttctg aagtctctag ctcacatctc atatttataa
    23041 tttcatcagt actcaaatat tcaaaacaat tttcatttgg aatgatgctc tcttttggat
    23101 ttcccaatcc tctagcattg ctttgtccta ttaataagaa tacatctata ttttccataa
    23161 gttaactcct ttacaaaatt ttaagctttt aattattttc aattttctca taaaaaacta
    23221 aggctgaaaa tagtaatcta actaaaattt acgaagtctc actaatcgct gaaagttaaa
    23281 tcactatttt cagccctagt ggttatataa attatcatta tctaaccaaa accttaaaaa
    23341 tagctttttt gatattttct ttttctaaaa cttttattcc tgtcatatga gcatcttctg
    23401 gataacaaac taaaaaatca ccttttctaa gttccatgta tccattattt ttaccatcaa
    23461 gaggcaagaa atcgcccttt tcttcatata ttttttgttc taaattttct ataaaattta
    23521 tatctattcg ttcacatcca tcaagcatca aatgaacatc tatatacttc ttatgagctt
    23581 cccagaatct atcttctttt tcacaagttt tatactctac aatattcaca aaaatatcat
    23641 caccatctat tgtataagta cctttttcat aatctattaa tgaattatct ttagcatatt
    23701 caaaacatct aagtaaatct tcatgcaatg ttgaatatgt cttactatga tttatatttc
    23761 caaatatcat aagcactatc tccctatata attataaagt ctatttttat acttttgtat
    23821 acaaagtata ttatacaatc ttatagagta actaaattat ttatctaatc actctataag
    23881 acaatttctc atttaaatat tatttttcat aataaacagt agtctcagct tttggtaaag
    23941 atacttttgc tttaacttta gcttctattg cactaactat tgtacctacc actacagaag
    24001 tcgtgattgt tattagagaa tatgcccaag aagttacttc tggcatacgg tattttaaat
    24061 aaacaactaa aattgctgat actatgaatc caacatatgc tcccatttta gttgcttttt
    24121 tacaaaatgc accaagtaca aatattcctg ctaaaacacc tagtactagc cccataaaac
    24181 tattaaacca ttcatatgct gactttattt ctccatttgc taatactatt gcaacagcta
    24241 tagaaagtat acctacacct aatgatatat attgtgctat cttagtttgc ttttccatac
    24301 ttatatcttt tgttatgata gtttgtatat ctaaagtcca acttgtagca actgaattaa
    24361 gccctgtcga taaagttgat tgagaagctg catatatcgc tgcaagtagt attcctgtta
    24421 tacccactgg taattcataa gctatatatg atgcaaatac ttggtcttgt tgaactgttt
    24481 gagctaaatc tgggttttga gtatagtata taaataaaca agttccaatt agataaaata
    24541 ctgttgcaag tcccattgat aaaacaccat ttccatatgt cattttatta agttgcttta
    24601 tatcagttgt tgtagtaaac ctttgaacta tatcttgact cgatacatat gatgaaaaag
    24661 tattaagacc agctccaaca aatattataa atgcacttgt agatagtata tttttatcaa
    24721 acataacttc attacttgct aagaacttgt gtccagttgt aagagtatcc attactgttc
    24781 caaaaccacc atttatactt gctattaaat agaacaatgt ccctgtaaca cctactatta
    24841 ataccattcc ttgtataaaa tcggtccaca agacagcctt taatccacct gtatatgagt
    24901 aaattattgc tattacaccc ataactatta tcagtacatt tacaggtatt cctgtaagac
    24961 cagccagaac tattgatgga agatacatta taatagacat acgtcctatt tgatatatta
    25021 taaacatcaa agctccaagt actctaagac ctttactttc gtatctcatt tctaagtatt
    25081 catatgctgt atctatttct aacctactat atagaggtaa gaaaaatttt attgtcaaag
    25141 gtattgctat aaacatacct aattgtgcaa accacaaaat ccaagtacca ccataagaat
    25201 ttcctgctaa tgataaaaat gatattggac ttaataatgt ggcaaatatt gatactgatg
    25261 taacccacca cggaatagtt ccatcacctt tgaagaactc ttttcccttc atttcctttt
    25321 ttgaaaataa caatcctgca aataaaactg ccaataagta aaccactagt attgcaaaat
    25381 ctatccaagt aaatcctacc attcgactaa tcctcccata ctaaaagtat tttattaaaa
    25441 atactttctg tatatttctt ttgctcttga tttcatttca tcagttgctt ctttcatagg
    25501 ttgtctacag tatccagcct caacaccttg ttcttcaagt agtaatttaa ttgtttgata
    25561 taagccattt cctaatatat ctgttattaa atcattagtc acatgttgta cttcaagtgc
    25621 ttctgatatt ttttcattct tagttaattc gaatatttgt ctagctctga caccgtttac
    25681 attgaatgta gaaccaattg ccccatctac acctaaaact gtagctggta acatcatttc
    25741 atcaaatcct gcaaatatta atttatttgg gaatgttttt ctcattctct ctaataagta
    25801 gaaatctgct gctgtaaact taacacctat tattttttca ttttcaaata attctccaaa
    25861 ctggtctaaa ctcatatcaa caccagttaa aaatggtata gagtatatta ttaatctatt
    25921 atctacagaa tttattattg tattataata gtgttttatt tcttcaaaat caaatttata
    25981 gtaaaaaggt gtaacagcac ttattgcatc atatcctaaa tcagttgtaa atttagcaag
    26041 ttctacagct tcttttaaat taactgaacc aacttgagct attaatttta tttcttcttt
    26101 cacttcatct ttagctattt caaatattct tttcttttca tcagttgaaa gcatgaagtt
    26161 ttcccctgta cttcctccta cataaagacc atctacttta caaacatcta tattgtgtct
    26221 aattatttgt cttaaccctt tttcatttat atttccttcc ttatcaaatg aaactaataa
    26281 tgctgaataa attcccttca tatctgttgt tctcatatct ttacctccaa ttttaatttt
    26341 caaatatagt taaatataat aattttttaa tttataaatt aatttttaat taatttcaat
    26401 tgctttaaca aatttttctg ttattaattg tggtcttgtt attgctgaac ctactactga
    26461 tgaatgaaca cccaactcaa agaccttttt taaatcttga ggagtattta cctttccttc
    26521 agctattaca ggtatttcta aatctttaac taatctttcc attaatacaa aatctggacc
    26581 ttctaatgtt ttagtatatg gagtatatcc agatagtgta gttgaaacgc aatctacacc
    26641 gtactcttgt gctttgatag cctcatcata atttgaaata tctgccatta ctagaacacc
    26701 gttttctttt atatacttta taagttcttt taagtcttca ttatttggtc taactctatt
    26761 ggtagcatct aatgctatca tttcacaccc tgttgttaaa agttcatcaa cttctttttt
    26821 agttggcgtt atatatatat ctgaatcttc atagtttctc tttataatac ctataacagg
    26881 aagtccagta acttttttta tttcaataat atcttcaact ccttgagctc taattccaac
    26941 agctccacct tccatagcag ccttagccat tctccccatt ataaaaggac tatgaagagg
    27001 ttcatcttct aaagcttggc atgatactat taatcttccc tttaccttat ctagcatttt
    27061 ttaaattacc tcgtttctga aatttatttt cttgatttat gtattaataa taacatgaaa
    27121 actttttctt tgcaatattt tttcatattt ttttctcaca tctatatttt tactgattta
    27181 ttttatatat tagcttgttt tttacattta aaagaaattt tatttcattt tttcggtgtt
    27241 tattttcatt ttatataact actgttataa gtccatttaa ataatttcaa taaaaaaacc
    27301 catgtatact atacataggt ttcccaatat tattctaaat ctattataat ttttcttcca
    27361 cagcatggac aaaattcagc ctctgtatct atctcacttt cacaataacc acaaattata
    27421 aaatcatcac attcattttc caattcaaat tttttaccac attcagcaca atatttatca
    27481 tttacatttc caacataacc acactcacaa gttacattac tttctgccat ttccatttca
    27541 ttaatttcca tatttttttc ataaattaac ttatcaagtt ctagtaactc atcacataat
    27601 ttatcaaaac tattatcatt aatagaatct tctctaattt tttgatatgt cagtattccc
    27661 atttccaaga atatctttgc tttctcttct tgaatatcat caatctctct atttaatttt
    27721 gatttttctt tatataattc aactttaaat tttccactac caaacttttt cttaacctta
    27781 gaaaatttat catctacttt attattagta tttccttcca cagaaattcc ctccaatcat
    27841 atttaatcag ctgaatttag cttatatcct attaaagata tcacaaaact atatacaaat
    27901 gaaatcacaa tagcttgtaa gactttaaat tgcattatta aagttgttcc ataattagtt
    27961 gtattaaaga aattaatatt actatctagt ataaatgtac taaataaagc caatattccc
    28021 atcaaaaatg cataatatat actaaatact attataggtc ttatactatc tgtattatac
    28081 ttaaatctta gcttgtatcc atttaataat aatattaaca tagacaatgc tcccattgca
    28141 taaaacatta atttagtatc tccaaataaa gatgaagaac ttaaagtaaa cattgatact
    28201 gttgagttta ttatggttac tgaaattcca tttgcaaaag cccacatata actagctatt
    28261 tgtgggagta tagtaaataa atttaatcca tttgaataac tactcatatc tagttcattt
    28321 aagtaactac tatcagatat agttagtacc aatagtatta ctaatactaa aacataacct
    28381 aatatgaatg ttcttataga atttgaaaaa agagataaat acatattttc tttttcataa
    28441 ctttttttat aagtagttat gtatgtacat ataaacccta atacgaatcc atttaaaaga
    28501 acactaaaaa attcataact atattctaat gcatatccat attctaacat actatgtgaa
    28561 ctagttttta cattagtaaa aatagataaa atagctaaaa ctaatccata aaaaattcca
    28621 actcctagag aatttgctaa tacagttttt gaatctctac atctttttct cataaaaatt
    28681 aggtttgata ttaataatac caaaataggg attataagta atatcaacaa acctatattg
    28741 gcatttataa acccagaacc catcatggta gacatagata cactaatttg acccaagttg
    28801 agagctagga ttatatgtgc tggatttact aaataactaa tatcattaaa ttgaatagtt
    28861 ataatagctt taaatatcaa tgcaataata aacaatataa atatggttgt aaatgttgtt
    28921 aaaaatacac ctcttttatt tgcatgatat gaaagctctt ttattttaga tttcaagtct
    28981 agttttgttt caagtggtct taatgatgct atttcataaa gttcatttcc acaaaattta
    29041 cagtaattat ccttagtatt attttcttta ttgcaactag aacaaatttt ttcttcttta
    29101 cttttaagag tgatatggct attttttatt tttctagttg gttcacctgt ctttttggaa
    29161 taattattat gtgaataatt catattattt attttctttt cacccatttt ttccctccaa
    29221 gttttactat tgtaaattat caaatataac tatatcatat aaaacttaat tataccttaa
    29281 ttggatatat ttatctattt tatttgttta ttgctgttgt tttttaacag ttcttgatat
    29341 ttaaatagtt tgttaatgcg aactttatta tttatatttt attatgctta atttaaattt
    29401 attctattct ttattttcag tagtaaacta tctgtaaatc ttaattataa taaagtatta
    29461 atcaataaag ttactcgaca ttatctaata aattttatct atcacaattt tagattgtta
    29521 cacacaatat attttgatat aattaaatca taaacgaagt attccaaata tctaatgata
    29581 gaaaggaata cttattttta tgctttattt ttaatggagg cttatatgaa cttagaaaaa
    29641 ataaaaaaat tttttggatt tcctctagac aaaaaacaca aagacaatgt tgagaaagaa
    29701 ctctgcaatt atctttatca tacgggtaaa atcatttgca taataatagt aatatctcaa
    29761 ataattatga tgatatcaat ctcagctaga gaaggaggcc cttttgtcac accaagacgc
    29821 caatggtatt tttatatgta tgtaacacta ttttgtgtat cttctgtctt tatgtttgta
    29881 ttttcttacc tttggaataa aaaaaaggat tgctgtacgt tttatataaa tttatggata
    29941 atttatgtga cttttttctg cctatggggt tgtgtaatta ctctacttga ccagttaggt
    30001 ggaaatgacc taagtgtatt tagttatatt atgttagcag ctgcagcttt ctcagtatta
    30061 aaatttggag aatcagtaat agtttttgga ggatgctttt tgtttcttaa tttattctta
    30121 cctgggattc aaactatacc aggcaatgag tttagtaata ttgtcaacac attttttata
    30181 acatcccttg ccatttttgt ttctacaatg ctatatagaa atcgtgtatt tacttactat
    30241 gataaacttt taattagtca acaatatgaa gaaatatctc atataaataa tttacttaac
    30301 gacaaagtta tgacagatga ccttactaaa atgaacaacc gtagatacct tgaagatatt
    30361 ctacaaaaaa aattaatcag ccatgcaaat caagaaccta taactggaat gatgatagat
    30421 atagattatt ttaaacaatt taatgataat tatggacatc aaaagggaga ctattgtcta
    30481 caaaatattg ccaaagtaat tttagatttt acaagttctg aaaatgaaca tgctatacga
    30541 tatggtggtg aggaattttt tatatgtatt tttaactgta atgaggcaga tgctaaactt
    30601 aaatcagaat gtttacgaaa aattatagag tcctgcaatt ttgagcgtga tgatgttcct
    30661 ttaaaatgtg taactgttag tattggagtt tatacaaaga aaattggaaa gacaataaca
    30721 ttaaatgagt ttataagtaa ttgtgataag gccctatata ctgcaaaaga acaaggacgt
    30781 aattgtgttg cattttatta aaaggttaca tactattaca taaacctata agtattatat
    30841 cgcaaaataa aagtaatcaa attatatatt tatagtacaa taaaaataac ttgcatatct
    30901 ctaaaataga taaatatgca agtcatttta gtgtttatac ttaaagttat ataagtttta
    30961 ttatatataa ttattaaaat tcagcatttt taggagttct tgggaaaggt ataacgtctc
    31021 ttatgttaga catacctgtc atatacataa ttattctttc aaatccaaga ccaaatccag
    31081 agtgagtagc agtaccaaac tttctaagtt ctaaatacca ccaataatct tcttctctta
    31141 atcccatttc attaattcta tctaacaata catcttctct ttcttctctt tgagaacctc
    31201 ctacgatttc tccaactcca ggaactagta aatccattgc tctaacagtt ttaccatctt
    31261 cattcattct catatagaaa gcttttatat cttttggata atctgtaaca aacactggac
    31321 aattatatat ttgctccgtt atatatcttt catgctctgt ttgaaggtca catccccact
    31381 caacaggata ctcaaattca tgcccagatt caattaataa ttccactgct ttagtatacg
    31441 ttattctaat aaactcagag tttactatct tatttaatct ttctaacaat cctttatcta
    31501 taaaactatt aaaaaattcc atttcttcag gagcattttc taatacatag cttataacat
    31561 attttatcat atcttctgca agttccatgt tatcttcaag gtctgcaaaa actatttctg
    31621 gctctatcat ccaaaattct gaagcatgtc ttcctgtata agagttttca gctctaaatg
    31681 taggtccaaa agtataaacg tttctaaaag aaagtgccat tatctcggca tttaattgac
    31741 cactaactgt taaattagcc tcttttccaa agaaatcttg agtatagtct attttgccat
    31801 cttcagtttt tggaatatca tttaaatcca tagttgttat tctaaacatc tctcctgcac
    31861 cttcacagtc actacctgtt atgattggag aatgtgcata tacaaagttt ctttcttgga
    31921 agaatttgtg tattgcatag gcagctattg atcttactct aaatacagct gaaaaagtat
    31981 tacttcttgg tcttaaatgt gctatcgttc ttaaatattc aagcgtatgt ctcttctttt
    32041 gtagtggata cgaactatct gattcccctt ctacaactat gctttttgca tgtatttcga
    32101 ctggttgttt agccccttct gtagatacta actctccctc tacaagtata gatgagctta
    32161 ttgctaattt tcctacctct ttaaaatttt ctactttctc atcaaatact atctgcatat
    32221 ttttaaagaa gcttccatca tttagctcta taaatccaaa atttttagat actctagatg
    32281 ttcttatcca tccagctact tttacagtct tccctatgta ctgttctttt tctctgtaca
    32341 attcttttac tgttataaat tccttttgca ttttaaatcc tcctagtata attgttatta
    32401 atttctttta aatataattt caataaaaaa agcccttcat ccctatataa agggacgaaa
    32461 gactattact ctcgcggtac caccctagtt gtcataatga cctcttagtt aagcaatgct
    32521 taaagcctat aacggtgcct tccgtctaag tctacttact aaataagctt tcgattagaa
    32581 actccaagat gttcttcaat ataaacctcg tattgagctt tcaccatcct caactcgcta
    32641 gaactacatt ttatatctac tcttctcttc acagtattta tcttttatta tttctgctaa
    32701 ttaacaaaat tataccaatt tataaatttt tagtcaataa atttatataa ttgatactga
    32761 ttgttattta aaatataata attctacctt acataatgat aataaatact tatcttcatt
    32821 acttctttat tacttcaatt tccaaaattt tataatttac ttccattgtc aacccagtct
    32881 tttgcttctt cgacaccctt aattgaaggt attgaaactt tactatgagg ttttaatttt
    32941 tcaacatcag cccatgctgc tgtcgactca tttccaacta aaagtgaact tttaagtctt
    33001 ttattatctt taccttttaa tgctcttgcc tttttacttt ccaaaactat cacctctatt
    33061 atttattttg taatagtttt agcaatttta caaataaaat tcataagtct aaattataat
    33121 tatttttaaa ttaacatcat atcttttcaa tacttaattt atacctattt atatacaaaa
    33181 tatttacttt gtgtattcaa aatataaaac tgttttttaa ttttcatatt tattttttat
    33241 gctatttttc tactctatct aaagtatttg atacaattaa actaataatc aattataatt
    33301 ttacataggt tcttatctat agagtatttg ctatctgttg aatcgtattt tttaaattta
    33361 aaatcccata tccctgcgat acatttggat atgtatatat ctcaagtttt gtagcaccca
    33421 atattaaata tgtttttaaa acttgtgtaa acaatgataa tctcggtaca ttatcctgtt
    33481 tttctaagta ttccatcaat aaggctaaaa cacctgtgac tatagaactg ctcactcctg
    33541 ttcctgttcc tgtattatat gttccatttt tatatgtgga tattatatct acacctgaag
    33601 ctactatatc tggcttaatt cctcttcctc taattggtcc tttcgaagaa ccaatccaca
    33661 tactatcagt cttattgtta aatgtaccaa ctgtaattac atcatcacta gcagcataca
    33721 tagttatagt agctactgaa tcagggtcta aaaaccttgt gtctggagct atcaaatttt
    33781 tatttggcaa gtatatgtca tattctccat ttattataag ttctgaagtc aatcttaaaa
    33841 tccatactcc aggttttata tctcttaatc ttatctccaa attttctttt ccagaggtaa
    33901 tatatggata aataaatctc attgcataag tagtattttc taagttaaat tttcctctat
    33961 atatataaaa gtctggagaa taccttatat catgactaac ttcacctgaa ggagatatta
    34021 tctgtgctcc cactttatct ggaccattcg tatttagtgt tatatcaaga gcatagtcat
    34081 ctccatcttg tattattaca tcttgaactt ctcccacact gctaaatctg ccagaataat
    34141 gaatatctgt attcccttga tttcctgcac cactcactac taccacacca gcactactca
    34201 atatattaaa agtatctagt attgaagtag ttgctacagc acttgactta actccaatag
    34261 tcaaatttat tatcagtggt ttattttctg ttcttgctat gttagtaaca tacgttatag
    34321 ctgctaaaaa atctgaaaca ctgtaattta tccttccagc ataataagta tctgtatatg
    34381 attttaattt aactactatt aagtctgatt ctgtagtaat acctctgtac tgagaattta
    34441 tccttccatt tccaactaat ataccagaaa ctaaagttcc agtacctata ttatcttgac
    34501 tcaaactccc atcatttcta tttatggcta tatttaactc acttcttgta aattcacttc
    34561 caaaaataaa accttctgga ggtggatttg tatttgcttc ttggtcccat aaatataaaa
    34621 ctttactagt tccatcatca tttataaaat caggatgcaa ataatctatc ccagaatcta
    34681 taactgctaa taaaattcct ctccctgtta tatcattata tggattttca taaatataat
    34741 cagtttcagc tgctgttgta atggtttctc cattatttac attattagtt atttcaatta
    34801 gactgctcat tggttcagat tcttcccacc aagcaacttg tattatatta tttaaaatag
    34861 tttcatcaaa atctaaaggt acatatatta ctgcaagctg actatttaaa accatatacc
    34921 tatttattcc attttcttgt agggcagatt ctatatcacc ttgataaatt atacaataag
    34981 atttttccat aaatccctcc tatcttaaaa catcaaacat tcctctaaca tccaagagcc
    35041 catatccaga atttgtattt ggatatactg tgtttgaatc ttttctagca ccagcttgca
    35101 taaaagtttt tattttttgc acatatgctt ggtttggata tctaccgtca acaaaagtat
    35161 attgaaaata cattgcagca gcaccagctg catgtgcact tgctgctgct gtaccagtta
    35221 tagttgcata cgtgttccca ggataagcag ctattatatt gacacctggt gctactatat
    35281 ctggttttaa cctgtcttca atagttggcc ctcttgatga actttgccat aaactaccat
    35341 taatagtatt gtaggctcct atggttatta aatcatcttg aatcgcagga taatttatag
    35401 tgtaaaaagg gtctacctct ctaaatctag ttccactttt taaaagttct ctatttggaa
    35461 ggtataagtt atatcttcct gttataatat aaactcctac taatcgaatc ttccatacac
    35521 ctctttttgc attctttaaa gtaacattag taaattgctg tccagaaaaa gttgttgggt
    35581 atatatatgt tatagaatat tcagtcccct ctaaatcaaa taaacctgtt actttattat
    35641 aatttgaaat tccaacactt ttactttctt caccagtggg agatactatt attacatcag
    35701 ctttatctgg tctatttaac caaagttcta atgataattc ttcctcgtct tcatttaact
    35761 ctaattcaac ttcaacagaa cctccaacat atggtattat tccagatgta tgtgtctgtg
    35821 tattgccctc atttcctgct cctgccgtta tacataaccc tctagtaaag aacgcttttt
    35881 cactattact cctattggtt aaacctgcta ggctactggt acctaaagac atatttataa
    35941 ctaatggtct tccaagttca aaagcttttt tatatgcata ctgagatgca gcaaacaaca
    36001 ttgcactatt ataaaaatca tctatcttgc cgagttttat tattattagc tcagaatctt
    36061 ctgctatacc tgcatattca ctatttacat ttccaagccc tgcacatatc ccactcaaca
    36121 tagttccttg accaacttca tcctgagata gactagggtc attttctgcg atagctcgat
    36181 ttatatcttc tcgtgtatat tctgtcccaa tataaaaacc atcaggagga gttccttctt
    36241 ttgtttggtc ccataaatat actatttttg aagtgccatc tggataaata aaatctgggt
    36301 gtagatagtc tattcctgta tctgcaattg atattagagt ccctcttcct gttatattaa
    36361 tattaggatt atttttaaag aaatttacgc ccatttcttc tgttgcaact acacctccaa
    36421 aagtacctcg attaatttct ccaagtaatg tcatctttgt agtcgataca gttcttatga
    36481 ttgaaggaag ttgcaaaact cgttgtatgc tattatagtc tgtattattt atagatagta
    36541 cacctaatga atcacttatc ttaaaaaacc tttgactcat acctaaccca gctagttctt
    36601 cttcaaattc aggagtatgg actatatcta ttcctgatag tattcctgat tgtctacttg
    36661 catttttact tatataaatt tcattctcta agtcattatg tatttgcata ttataaccat
    36721 ctataaactt ataactattt tcctcatctt taaatgactt attaatactt ctatatccaa
    36781 tatcctctgt ttctaaatct tgatttatat tagatagagt gtacaaatct atatctgata
    36841 aatttaaaaa accaaatcct gatgaattat ttggataaga ttgattactt aatctccttg
    36901 ctccctttag aagtaatgcc cttaatttct gtgaatacaa aaataaatca tttccattta
    36961 caattcccca ttccataaac aatgaacaaa cccctgtaac atgaggtgta gccatgctag
    37021 ttccagttaa tgctccactt gtacctcctg gtaaaaaaga tactatatct tcacctggag
    37081 ctaataaatc aggtttaaaa acacctaatt gtgtatctcc ttcaccagaa aatatagata
    37141 ctatatctgt tcttgaatta aaactaccta ctgttataac tctacttgct gttccaggaa
    37201 ctgttacagt aagctcttga gtaggaatca gaaatctagt atttctattc agaccttcag
    37261 aagttggcaa atatatattt acattaccag ttactatatc tattggttca aatacaattt
    37321 tccataaccc aggagttatc tgtgtatttg aacttaattg tagagtaact cttcttgtga
    37381 gagaatacgg tgctataggg taaaaataac cagttattct agtttcaccc aaagtattcc
    37441 ttatctcacc tgaagttaga gagattgctt gtgtttgatt atttgatggg tttaccaaat
    37501 gtacactaaa atcatcaaca aaatctggcc atatatttat gtttaatata cgctctcctt
    37561 ccccaactat aaactcaact tcttctgtaa tattattttg aagcctaatc cttttatgac
    37621 ctcctttatc tgcattattt ccagctgcta caactatatt gtttttccaa aataaacaca
    37681 tatcatctat atattgttca aataaagatg ttcctctatg tgaaccttca ttacttccat
    37741 aacttatatt taatgtaaca ggcattctta attctaatgc cctatctaaa ataaatttaa
    37801 ttgccctcat aaactctgta cttctcgaaa aaatatcggt ctgtatattt ccaactctaa
    37861 ccactattat tctggcatca cttgcaatag ttgcacaaat acctgcaaca tgtgtcccat
    37921 gtaagctagt tgttgaaata ggtatataca tacttccatc tattgcatta tttatatctt
    37981 cattagtata taatgttcct tctctaaaac cttctggtgg atttccttga atagattggt
    38041 cccaataata taatatctta gaccttccat cactatctct aaacacaggt agagtataat
    38101 ctattcccga atcaattata ccaattatag ttccttttcc agttaaacca gttctatttt
    38161 taaatcctgt tattcctgta cttgaaaaac tttgcacatc ctgagtctgt aatataaaag
    38221 gcttttctat aaattcaatt tctggataag ttaaaagtat atttacatct tcttcattac
    38281 ttgatgttat tattgcatat gatgaattaa gtatctctac tgatacacct aattcttctt
    38341 ctaacctcaa tatatctcca ttgtatttta caattaattc ataatttatt ataatcacct
    38401 cgacttctaa aattattatt aatgtatatg ttttgtgtga gtctaaaatg tattagacta
    38461 tataattttt taagtttcag ttatacaatt tataatagat atattaaaaa aaataaataa
    38521 tgatggtaca attttgaata aatcatacca tcatttatat ttactttatc ttgaaaccat
    38581 taaatttttc aatgctttct caagaccttt tacagtcaat ggaaacatat taaattcact
    38641 ttgtatcatt ctttgagttt gataccaata attaattgaa tcccatccat ctctaagttc
    38701 tggattcatc catacaattt tactgtactt tctcttaaac cttttaagcc actctatacc
    38761 aggtgtgtaa ttatatggac cacgatagtt accaccaata tgaagcaact cagaaggcga
    38821 catagaagca tctccaacaa ttataacttt atagttttta tctatatttt ttaatatcca
    38881 ttcagtatta atagatttac ttaaccaaca ttcaggtgtt gtaaataatc tatcataaat
    38941 acagttatgg aaataatata tctttacatc tttaaaatga tttgatttac ttacagactg
    39001 aaataatgta ttacataaag tgctataccc tctcattgaa ccacctgaat ccataagcaa
    39061 taaaagcttc actgtatttt ttcttggctt ctcaaaaaat aactttaaat atcctgcatt
    39121 attacaagtc tcttcaatag tcttatccaa atcaagctct gtctttggag catctattct
    39181 ggtagaaaat tgacgaagtc tctttagtgc aacttgaaat tgacgcatat ttaaaacttc
    39241 atcatctcta aaatctctgt attttctttc tcctgcaact tcaagaacag ctctaccata
    39301 agtagaattt ccacctatac gtataccagt ttgccctttt cctgaatgtc ctaactctga
    39361 agtgcctcct gtgcctatcc aataattacc accattatga ggagagtctt gttcttttat
    39421 tcgttcctcc aatttagctc ttaatttatc aagatttata tttggatttt gttctaatct
    39481 ttcaaactct tctaaatcta tatctggttt tttaagccaa ttcataatct cttctggaat
    39541 ttcttcttgg tgttctatac ctttaaaata ctccaaaaac actgcatcaa acttatcaaa
    39601 atcactttca ctttttatta aaatcatcct gcaaagatag taaaaatttg aaaagtttga
    39661 atagcacagt cctttatcca atgcttcaat taaagtcatc cattcattta aagatacatt
    39721 taatcctctt gacctcaata aataaaaaaa ttcaataaac ataattatcc agctcctatt
    39781 aactataagt gtctttgcat agattcaata tcctcattat tcttaagtag tattcctgca
    39841 aaaggaactt ctttttctat tttttcaata ggcattccac tcaaagttaa tgcttgtatc
    39901 cagtctatta actctgatgt actaggcttt ttttgtatgt cctttaaact tctaatccaa
    39961 taaaaagtag tcattacttg ttccaatagg tgttcttcta ctttatcaaa atgtacttta
    40021 actatttctt ccatcatgtc tctatcagga aattctatat aatgaaatat gcatcttctt
    40081 aaaaaagcat ctggaagttc tttttccgca tttgaagtta taataactat tggtctttgt
    40141 ttagctctta cagtttcttt tgtctcattt atgtaaaact ccattttatc caattcccaa
    40201 agcaagtcat ttggaaattc taaatccgcc ttatctattt catctattaa aagaattact
    40261 tgttgatttg agctaaaggc ctctcctagt ttaccatatt ttatgtactt gctaatatca
    40321 tctacacctt ctcctccaaa ttggctatca taaagtcttt gaacagtatc atatacataa
    40381 agcccttctt gtgcttttgt agttgatttt atattccaaa ttactaaatc tttttttaat
    40441 tcatttgaaa ttgcttgtgc tagcatagtt ttacctgttc caggttcgcc cttaatcaaa
    40501 agtggctttt caagagcaat agcaacatta actgatgcca tcaattctgg tgatactaca
    40561 taatcactac ttcctctaaa gttagatatc tcttttttta tcataaatcc tactcctttt
    40621 aaacagtatt ttctaaatgt atatagactt tattactatt tttgatataa aaacttacta
    40681 aatttctgat tatcttttca taagtt
//
LOCUS       DAMKNB010000243        18265 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.guided.074, whole genome shotgun sequence.
ACCESSION   DAMKNB010000243 DAMKNB010000000
VERSION     DAMKNB010000243.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 18265)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18265)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18265
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.guided.074"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            complement(<1..658)
                     /gene="bclA1"
                     /locus_tag="PC494_003831"
     CDS             complement(<1..658)
                     /gene="bclA1"
                     /locus_tag="PC494_003831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-like exosporium glycoprotein BclA1"
                     /protein_id="HDF3914228.1"
                     /translation="MRNIILYLNDDTFISKKYPDKNFSNLDYCLIGSKCSNSFVKEKL
                     ITFFKVRIPDILKDKSILKAELFIHIDSNKNHIFKEKVDIEIKRISEYYNLRTITWND
                     RVSMENIRGYLPVGISDTSNYICLNITGTIKAWAMNKYPNYGLALSLNYPYQILEFTS
                     SRGCNKPYILVTFEDRIIDNCYPKCECLPIRITGPMGPRGATGSTGPTGVTGPTGSTG
                     A"
     gene            complement(1336..1860)
                     /locus_tag="PC494_003832"
     CDS             complement(1336..1860)
                     /locus_tag="PC494_003832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HDF3914229.1"
                     /translation="MENKNPIVTIEMENGKEIKIELYPNIAPNTVKNFVSLVNEGYYN
                     GIIFHRVIPGFMIQGGCPNGTGMGGPGHSIKGEFSGNGFTNNLKHERGVISMARTMAP
                     NSAGSQFFIMHKNSPHLDGQYAGFGRVIEGMDTVDEIASVRTDSADKPQTPQVMKSVT
                     VETFGIDYSDVEKN"
     gene            complement(1925..2677)
                     /locus_tag="PC494_003833"
     CDS             complement(1925..2677)
                     /locus_tag="PC494_003833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
                     /protein_id="HDF3914230.1"
                     /translation="MKLGLCLEGGGAKGAYQAGVVKALYDGGINKFYSISGTSIGAIN
                     GYYLYTGNVDNLEKMWTNIKDIQNGNVKIVNNTVDNSPAIDNLRELDDSNIEEMNFYV
                     NYVEVDNKVVSEKIVDVSKMPRNEAIISISYSGLLPSNPNATLGFKEQFVKDVQEGIY
                     DGFKLDGGLIRSALIEPLIGDNVDKIILISTKYNYELPEDIKKVYDEDKIIVVRPNTQ
                     FAPKDTLNFDDEFCKTIYQEGYEIGKNILDRL"
     gene            complement(2708..4006)
                     /locus_tag="PC494_003834"
     CDS             complement(2708..4006)
                     /locus_tag="PC494_003834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M18 family aminopeptidase"
                     /protein_id="HDF3914231.1"
                     /translation="MDSINFAKNLIDFIYDSPSSFHAVESTKEILDKNGFEELVLNQR
                     WNLRVGGKYYVTKNLSAIVAFVVNSEGIERDGFRIIGSHSDSPTFSIKPNAEIEAEKS
                     YLKLNTECYGGAILSTWLDRPLGIAGRVVLKGDSILKPNERLIDFKKPICIIPNLAIH
                     LNRSINDGHSYNKQKDMLPLVGMLNDTLEKDNFLIKQIASNLDVNMEDIIDFDLFLYE
                     FEKGSLIGANDEFISIGRQDNLAMVHASLNALVNTKGQHGVNVMAVFDNEEVGSSTKQ
                     GADSNMLLNILERICISMGKDREGFFESIYSSFMISSDLAHAIHPNIPEKHDPTNKPI
                     MGKGPVIKINASQAYTSDGYSIAIYKNICREANVEYQEFVNRSDERGGSTIGPISSTH
                     IDIPSVDVGSPILAMHSIRELGNVEDHYSIYKTFSKFFEI"
     gene            complement(4023..6287)
                     /locus_tag="PC494_003835"
     CDS             complement(4023..6287)
                     /locus_tag="PC494_003835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3553 domain-containing protein"
                     /protein_id="HDF3914232.1"
                     /translation="MNLDTLNPAQREAVEKTEGPVLILAGAGSGKTKVLTTRIAYLIE
                     DKGVQAPNILAITFTNKAANEMRERVEQNIGPETKDMWISTFHSCCVRILRKDINKIG
                     YNRSFVIYDSADQVTLVKDCLKELNLSDKVFEPKAVISAISGAKDKLYTPKQFKDINM
                     ADNRMVKIADIYALYQDRLKRNSALDFDDLILKTVELFKANDEVLAYYRSRFRYIMVD
                     EYQDTSKAQYELIKLLAREHQNICVVGDDDQSIYGWRGADIRNILEFEKDYDNVHVVK
                     LEQNYRSTQVILDAANKVISNNIERKRKKLWSEKKEGELIKIQLTGSEIEEADFIADS
                     IAQIARKENRPYKDFAVLYRANAQARPVEDALNRSQIPYNIYGGTKFYERKEIKDLLA
                     YLRVIQNPQDDISIKRIINVPRRGIGLRTIEKIEDRANLKQESIYSVLIDIETNSDIS
                     TKARASISGFVDIIGTLRTIKEVYPVSKLIEKVLDTTGYMDELVEIRNKNEKDLTGKG
                     EEAQDRIDNLREFISIALEFESSNDDTYENKDLETFLTSIALTSESNDEEDNDRVSLM
                     TIHTSKGLEFPVVFLTGMEEGLFPISRAIKSMSDSQIEEERRLCYVGITRAKEELYMS
                     LTEKRTLYGKTNVAIASRFMEELPEECIERLYKVKKELSYSKASYNMLDKYTKKYMST
                     ISKSKVADKVNATIKDSNKETNPDDIKLGSKVHHPKFGVGTVVSIIGTDVTIAFDQQG
                     IKKINKEYTTLNIL"
     gene            complement(6542..7360)
                     /locus_tag="PC494_003836"
     CDS             complement(6542..7360)
                     /locus_tag="PC494_003836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HDF3914233.1"
                     /translation="MFKINNLTYQYEKNTNALLNINMDFSKGNVIGIIGSNGSGKSTL
                     FMNLMGILKPTSGEILFKEEKLKYDKRSLYNLRKNVGIVFQDPEKQIFYSKVYDDIAF
                     AMRNIGMDEKTIKERINKALVAVNGIDFIDRPVHFLSYGQKKRVAIASVIAMENEIVL
                     LDEPTAGLDPVSTRSIVDIIKGLNKNNIKIVISSHDMNLMYEICDYIYVLDKGILIDE
                     GKAENVFINENNIIQAGLESPWLVKVHRNMNLPLFKKEEDLYKYWKERELNTNK"
     gene            complement(7353..8051)
                     /gene="cbiQ"
                     /locus_tag="PC494_003837"
     CDS             complement(7353..8051)
                     /gene="cbiQ"
                     /locus_tag="PC494_003837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt ECF transporter T component CbiQ"
                     /protein_id="HDF3914234.1"
                     /translation="MLIIDKYAYTNRLSKVNPNKKVAIGVIFLIASMVIQNIFILSGI
                     MILMSILVVCVAGIDLKNYLKLLRIPMYFLFLSIGITLVNISFNKADLLYSFEFFSFN
                     VGISKASIDMSIHVLFRAMSCLTCVYFCILTTPFNQLIFFFKKLHLPDTFVELSMLIY
                     RFIFIFLEEFSEIYKSQELRFGYINLKTSYKSLGILGSMLYKRLMTRYDDMCISLDIK
                     LYDGKFHIVGDNDV"
     gene            complement(8054..8332)
                     /locus_tag="PC494_003838"
     CDS             complement(8054..8332)
                     /locus_tag="PC494_003838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     substrate-binding protein"
                     /protein_id="HDF3914235.1"
                     /translation="MSAKTKTNILLLLLVVALIIFPLLVNSGAEYGGADGQAESEITK
                     INPNYKPWFSSPYEPPSGEIESLLFSAQAALGAGVIGYILGLQKGKRS"
     gene            complement(8322..9074)
                     /locus_tag="PC494_003839"
     CDS             complement(8322..9074)
                     /locus_tag="PC494_003839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006440549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter permease"
                     /protein_id="HDF3914236.1"
                     /translation="MKQNIKLGVIAALMLIILTPVTSNAMHIMEGYLPVKWSIAWGVI
                     FIPFFLFGLKSIGKIVKQDPKKKVLLALCGAFVFVLSALKIPSVTGSCSHPTGVGLGA
                     IMFGPSVMFVLGTIVLIFQALLLAHGGITTLGANAFSMAIIGPIVSFLIFKALKKKDG
                     NNAIPVFLAAAIGDLATYTITSIQLALAFPDPSGGVMASAIKFLGIFFMTQIPIAIAE
                     GILTVIVYNLITENGEKSILENNDKGVKANEC"
     regulatory      complement(9256..9448)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00174"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cobalamin riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="adenosylcobalamin"
                     /db_xref="RFAM:RF00174"
     gene            complement(9580..11352)
                     /locus_tag="PC494_003840"
     CDS             complement(9580..11352)
                     /locus_tag="PC494_003840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitric oxide reductase activation-like protein"
                     /protein_id="HDF3914237.1"
                     /translation="MKWIYDDYEFENRANNLSWTIAGDYNESIDISEKDYSSKEIGLY
                     FAIIAGARRKYVDWDIVKKYLTNRIRKGYNKDIILGLIQVILNTIVEEKVIKDRPGIE
                     DIRRNAYKDIVSRFTKIHNDNIMDKIKYTFVLYSMDKHPALDSMTRRIVNDIRNIDTN
                     QDIMEILKALDVIYLTYFEYILNGEENSLIDENNVESVEVNFDTFADFMYEELYSDEE
                     ENIIESDIDSISSSMLVEGVGDFDDSKCSNSADRVIYVDEDTANKIYSKIEHYYGKTY
                     LSKGEIKKIETQNCRNVHEGCRIHFTDGVLRSECNNVFQLKYVTRQKENNLGKFREHA
                     RMYRQQIKRLKESLSRILIEENAKSRVYSDCGTILANRAWRVGRSNNNKIFYKDIENE
                     KGKYVIDILLDASGSQSRNQGNVAIQAYIIANALTEVGIPNRVMGFSSFLDYTILKRF
                     KDYDDSIKNSENIFEYFCAGNNRDGLAIKSICSGLINRDEENKILIVLSDGRPNDVKI
                     GKSSERTLRGEKAYRGIVGLRDTANEVRKARKQNILVLGVFTGKESELEAERLIYGND
                     FIYSRDITRFSDVVSMYLKKIIRN"
     gene            complement(11366..12295)
                     /locus_tag="PC494_003841"
     CDS             complement(11366..12295)
                     /locus_tag="PC494_003841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HDF3914238.1"
                     /translation="MDIIDNLRVQGVDEKLIEDVLYFRNYYGLEKDLEYRVTKSKTYF
                     YGKDILSMCIAAILEEENILLSGPKATGKNLLADNLGEIFNRPQWNTSFHINTDSSTL
                     IGTDTFIDNEVKLRRGSVYECAINGGFGVFDEINMAKNDAIVVVHSALDYRRIIDVPG
                     YERVNLHPATRFIGTMNYEYAGTKELNEALVSRFMVIDIPPIEEDKLMMILKNEFSDA
                     DEEKLIHFAGIFLDLQLKSQNGEISSKAIDLRGLMASLKTIRRGLKPTLAINMGLTGK
                     TFDVYEKEMVGDVIKTRIPNKWESIDVFPISHI"
     gene            12523..12711
                     /locus_tag="PC494_003842"
     CDS             12523..12711
                     /locus_tag="PC494_003842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF3914239.1"
                     /translation="MEYMSCPEVAKKWGISERRVQKLCEESRIPGVSKLGYMWLIPKN
                     AEKPVDGRTKRRKEVQYE"
     gene            12704..13405
                     /locus_tag="PC494_003843"
     CDS             12704..13405
                     /locus_tag="PC494_003843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF3914240.1"
                     /translation="MNSVLIIDDDKELCALMKKCVEQENLSAIIAHCGAEGLHLVDKN
                     RHTLSLVILDIMMPDIDGFQVLKKIRETSNIPVIMLTAKNDEDDKVSGLRLGADDYLT
                     KPFSINELMARVNSLIRRYTMLNPAFITDTDCIIINGMIIDKTNRIVSVNNIPVQLTS
                     KEFDLLAFLASNKGQVFTKKQIYTQVWEEEYAFDDSNIMSFISKLRKKIEPDPNHPFY
                     ILTVRGVGYRFNKEA"
     gene            13407..14330
                     /locus_tag="PC494_003844"
     CDS             13407..14330
                     /locus_tag="PC494_003844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF3914241.1"
                     /translation="MNTSVYLLLILVLSLIIIAYLVSVLLRVRIQLTLIKDALEDIKN
                     GNLNRRILTDENDITKQICYDINEIAINSQFQLIQQKQSEQAYKQLMTSLSHDVKTPL
                     ASLVGYLEAVESKIVVGEEKDEYIHVASNKAHYLKNFVENLFEWVKLDSKEQVFHFDI
                     FDLNELSRNIISDWIPVLESSHFEYEFDIPEIEYFLRIDANAYTRIINNLLQNIITHS
                     SGNKMTLRIFENKEQAQIIITDNGKGISSDNLPHIFERLYQCDHSRASKGNGLGLAIA
                     KELINAHKGNITANSTPGMGTEFTILLPKAL"
     gene            14487..15410
                     /locus_tag="PC494_003845"
     CDS             14487..15410
                     /locus_tag="PC494_003845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019639192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF3914242.1"
                     /translation="MNDFVIETKQLTKIYGNQTVVDKVNLHVKKGRIYGLLGRNGAGK
                     TTIMKMILGLTSITYGEVDVFGENIKEREKQVYPRIGAIIETPGFYPNLTGTENLEIF
                     AKLRGTAAPNSVKRALEIVGLPYKNKKLFSKYSLGMKQRLGIANAILHDPELLVLDEP
                     TNGLDPIGIAEMRKFIRDLSVEHGKTILISSHILSEISLLADDIGIIDHGVLLEESSM
                     SELEKKNSKYILLQVSDIPKTSLILERQFNTKDYSVQDDYTLHLYNTNLDMGEINKAL
                     VMQNVTVISSQLCNDTLEDYFKKITGGEGIA"
     gene            15403..16140
                     /locus_tag="PC494_003846"
     CDS             15403..16140
                     /locus_tag="PC494_003846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF3914243.1"
                     /translation="MLKLIQTEFLKLRRRKLIWLMLLSALIMPFFALLYFNYFGKTGV
                     EPIKFYKWSAFGYTLWIILPVVLGIFCTMLIHEENQYDMLKQLWIVPISKMGYFFSKF
                     FVVLIYSICFMLITAVASVLFSVLSGYVVFSWASILYLLKKCLEIGVITAFVMLPILA
                     IATSQKGYILPICITLVYAFSGFVIMTINMYLHPLSSMGVIIMRNKDIPGLIFSQEIN
                     VPLAFLCICIWSIVSVLFANIALGRRK"
     gene            16151..16924
                     /locus_tag="PC494_003847"
     CDS             16151..16924
                     /locus_tag="PC494_003847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF3914244.1"
                     /translation="MWKLLWAECQKIRRSKIVWITVFASIMIAVIVFAGGQDVYNDPD
                     LHYGLKSVYDGSRYIDNAGWYMDAVQPWSTFFVLPAVIALLGSYIICREEEEDTIKSL
                     RLIPINETNLTIAKMIITFIFSILLYLLLFTITFLTESVLHFSDLSTKLVLSCMKEYF
                     LDGIGVFFAISPIIALVSRMKKGYWLALVFTEVYSIAGLFAGMSNVLQTFFPIAAIFN
                     ISGYYITTGEKIMGSIISLLLCACLSAFILKGLKHNEKN"
     gene            complement(17451..18059)
                     /locus_tag="PC494_003848"
     CDS             complement(17451..18059)
                     /locus_tag="PC494_003848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DedA family protein"
                     /protein_id="HDF3914245.1"
                     /translation="MSVINSFILQYGLISVFVLIMIEYACFPLPSEVVLPLCGAIAAR
                     NHFGFLTILILSIIAGILGSIFCYTVGNWGGKSIINKIIEICPKAKKGIFASQDYFNK
                     YSSISVCVCRLIPLCRTYISFIAGIAGQNIITFVISSIVGITIWNTSLISIGYIFSES
                     WVRIMSHYNDYKFLVLIIPISIIFIGFVIKSFIHKKHHKIRL"
BASE COUNT         5927 a         3130 c         2259 g         6949 t
ORIGIN      
        1 tcgctcctgt acttccggtt gggcctgtta ctcccgttgg tcctgtactt cctgtcgctc
       61 ctcttggtcc cattggacct gtaattctaa ttggaagaca ctcacattta ggataacaat
      121 tatctataat tctatcttca aatgttacaa gtatatacgg tttgttacaa cctctactag
      181 atgtaaattc aagaatctga taagggtaat ttaaagataa agctaaccca taattaggat
      241 atttattcat tgcccatgct tttatagttc ccgtaatatt taaacaaata tagttggatg
      301 tatcacttat cccaactggt aaatatcccc taatattttc catagacact ctatcattcc
      361 atgttatagt tcgtaaatta taatattcac ttattctttt aatttcaata tctacttttt
      421 ctttaaaaat atgattctta tttgaatcaa tatgaataaa taactctgct tttaatatac
      481 ttttgtcttt taatatatct ggtattctca ctttaaaaaa agtaatcaac ttttctttta
      541 caaaactatt tgaacattta cttcctatta agcaataatc taaattacta aagtttttat
      601 ctggatattt tttagatata aaagtatcat catttaaata aagtataata tttctcattt
      661 ataatccctc cattttgggt ctatatcata ctatgtttaa aatacatgct tagttacaat
      721 ataattaaaa tttatagtat taaattttta tataataatg ctgatttcta caaaaaaaga
      781 acatgtcatt agaaatttct aatagcatgt tctttttcat tattatatat tacactttaa
      841 attattcctt gactggctta gctggtgtaa actaaaccag tctttctaaa atattaagca
      901 cttttttctt attatgtttt ttaggattta ttgtctatat tattgtaaac caaagttata
      961 aaattgtaaa tagaatatat taccataaca atatcttttt ataagtaaaa attataaaaa
     1021 accttatttt tattaaatag aataaataaa ataagtttaa aaaatactga aataagtgtt
     1081 ttccacatat tttatatatt tatttaatac attattattt aaaaataaat atataaacaa
     1141 tcataataaa atttttttaa taaaacttta ttttttagtt aaaatcatac aatatataga
     1201 tttccacaat acaaataaat taaaaagtga aatgtatttg tctaaaaaca taataacatt
     1261 tcactttatc ctcattttta agtaatatat atttttaatt tttatttata actaaatcta
     1321 gtttttatat aaattttagt ttttttctac atctgagtaa tctattccaa aagtttctac
     1381 agtaacagat ttcataactt gtggagtttg tggcttatca gctgaatctg ttctaactga
     1441 tgctatttca tcaactgtat ccataccttc tatcactcta ccaaaacctg catactgacc
     1501 atctaagtgt ggtgagtttt tatgcattat gaaaaattga gaaccagctg aattaggtgc
     1561 catagttcta gccattgata tgactcctct ttcatgtttt aaattgttag taaatccatt
     1621 accactaaat tcacctttta ttgagtgacc tggaccaccc attcctgtac catttgggca
     1681 tcctccttgt atcataaatc ctggtattac tctatgaaat attattccat tgtaatatcc
     1741 ttcatttact aatgatacaa agtttttaac tgtatttgga gctatatttg gatataactc
     1801 aattttgatt tcttttccat tttccatttc tatagttact ataggatttt tattttccat
     1861 aatttattac cttccttttc attagttaaa ttacataatt acatttatta tattatactc
     1921 taaattaaag tctatcaagt atattttttc ctatttcata tccttcttga taaatagttt
     1981 tacaaaactc atcatcaaag ttaagcgtgt ctttaggagc aaattgagta ttaggtctaa
     2041 ctactattat tttatcttca tcatatactt ttttaatatc ttctggcaac tcataattat
     2101 attttgtgga tattaaaata attttatcca cattatcccc aattaatggt tcaattaatg
     2161 cactcctaat taaacctcca tctaatttga aaccatcata aattccttct tgcacatctt
     2221 tcacaaattg ttctttaaat ccaagagttg cgtttggatt tgatggtaac aacccactgt
     2281 atgaaatgct gataatggct tcattacgag gcatttttga tacgtcaaca atcttttctg
     2341 atactacttt attatcaact tcaacataat taacataaaa gttcatttct tctatattac
     2401 tatcatctag ttcccttagg ttgtctatag caggagaatt atccacagta ttatttacta
     2461 tttttacatt tccattctgg atatctttta tatttgtcca cattttctcc aagttatcaa
     2521 cattccctgt gtacaaataa tatccattta ttgctcctat tgatgtccct gaaatcgaat
     2581 aaaatttatt tattcctcca tcatacaagg ctttaactac tcctgcttga taagcccctt
     2641 ttgctcctcc accttctaaa cataatccta atttcatagt ctcatctcca aattgtttat
     2701 cttatattta tatttcaaaa aacttactaa atgttttata tatactatag tggtcctcaa
     2761 catttcctaa ttctcttata gaatgcattg ctaaaattgg acttcccaca tccacagatg
     2821 gtatatctat atgagtagaa gatattggac ctatagtact tcctcctctt tcatctgacc
     2881 tattaacaaa ttcttgatac tcaacattag cttctctaca tatattttta taaatagcta
     2941 tagaatatcc atcactagta tatgcctgac tagcatttat ctttataacc ggaccttttc
     3001 ccattattgg tttattagtt gggtcatgct tttctggaat gtttggatga atagcatgag
     3061 ctaaatctga tgatatcata aaagatgaat aaatagactc aaagaatccc tctctatcct
     3121 tacccattga tatgcaaatt ctctccaata tatttaacaa catgtttgaa tctgcacctt
     3181 gtttagtaga gctaccaact tcttcattgt caaatacagc cattacattt acaccatgtt
     3241 gacctttagt attaacaaga gcattcaaac tagcatgtac cattgcaaga ttatcttgtc
     3301 tcccaataga tataaattca tcattagccc ctattaaact tcctttttca aattcatata
     3361 aaaataaatc aaaatctata atatcttcca tatttacatc taagttagat gctatttgct
     3421 ttataagaaa attatctttt tctaatgtat catttaacat cccaactaaa ggtaacatat
     3481 ctttttgctt attatatgaa tgaccatcat ttatacttct atttagatgt attgctagat
     3541 ttggtattat acaaattggc tttttaaagt ctataagcct ttcatttggt tttaatatac
     3601 tatcaccttt taaaactact ctaccagcta tcccaagagg tctatccaac catgtactta
     3661 atattgctcc tccatagcat tctgtattta acttcaaata agatttttca gcttctattt
     3721 ctgcatttgg tttaatacta aatgtaggag aatctgaatg agagcctatt attctaaatc
     3781 catctctttc tataccttct gaatttacta caaaagctac tatagctgat aaattcttag
     3841 taacataata ctttccacca actcttagat tccatctttg attcaaaact aattcttcaa
     3901 atccattttt atctaagatt tccttagtac tctcgactgc atgaaaagac gacggactat
     3961 catatataaa gtctattaag tttttagcaa agtttatact atccattcct catttacctc
     4021 cattataaaa tatttagtgt tgtatattct ttatttattt ttttaattcc ctgttggtca
     4081 aaagctatag taacatctgt accaattata gaaaccactg tcccaacccc aaatttagga
     4141 tgatgtacct tagaaccaag ttttatatca tctggattag tttctttatt agaatctttt
     4201 attgtagcat taactttatc tgcaacttta gatttgctta tagtactcat atacttttta
     4261 gtatatttat ctaacatatt ataacttgct ttagaatagc ttagttcttt ttttactttg
     4321 tacaatcttt ctatacattc ttctggcagt tcttccataa atcttgaagc tatcgcaaca
     4381 tttgttttac catataatgt tctcttctct gtcaatgaca tatatagctc ttctttagct
     4441 ctagttatac caacataaca aagtcttctc tcttcttcta tttgtgaatc actcatagat
     4501 tttatagctc ttgatatagg aaataaccct tcttccatac ctgttaaaaa cacaacaggg
     4561 aactctaaac ctttggatgt atgaattgtc ataagcgaaa ccctatcatt gtcttcttca
     4621 tcatttgatt cagatgtaag tgctatactt gttaggaatg tctctaagtc tttattttca
     4681 taagtatcat cattactact ttcaaactcc aaagctatag aaataaattc tctcaaatta
     4741 tcaattctgt cttgagcttc ttcacctttg cctgttaaat ctttttcatt tttatttctt
     4801 atctctacaa gctcgtccat atatcctgta gtatccaaga ctttttctat aagtttgcta
     4861 acaggataaa cttcttttat agttctaaga gtccctataa tatcaacaaa tccacttata
     4921 cttgcccttg ccttagtaga tatatctgaa tttgtttcta tatcaattaa tactgagtat
     4981 atactttcct gttttaagtt agctctatct tcaatttttt ctatagttct aagccctata
     5041 cctcttctag gaacatttat aatccttttt atagatatat catcttgtgg attttgaata
     5101 actcttaaat acgccaacaa atcctttatt tcttttctct catagaattt tgtaccacca
     5161 tatatattgt atggaatttg acttctattt aaagcgtcct ctacaggtct tgcctgtgca
     5221 tttgctctat aaagtactgc aaaatcctta taaggtctat tttcttttct agctatttgt
     5281 gcaattgaat cagcaatgaa atcagcctct tctatttcgc taccagttaa ttgtatcttt
     5341 ataagttctc cttctttttt ttcactccaa agcttttttc tttttctttc tatattatta
     5401 gatataactt tattagctgc atctaatatc acttgtgtag acctataatt ttgttctaac
     5461 tttacaacat gtacattgtc ataatctttc tcaaattcaa gtatgtttct tatatctgca
     5521 cctctccatc cataaatact ttggtcatca tctccaacaa cacaaatatt ttgatgttct
     5581 cttgctaata attttatcaa ttcatattga gctttacttg tatcttgata ctcatctacc
     5641 attatgtatc taaatctact tctgtaatat gctaatactt catcattagc cttgaaaagt
     5701 tctacagttt taagtattaa atcatcaaag tcaagtgcac tatttctttt taaacggtct
     5761 tgatatagcg cataaatatc tgcaatctta accattctat tatctgccat attgatatct
     5821 ttaaactgct ttggagtata aagtttgtct tttgctcctg aaattgcact tataactgct
     5881 tttggttcaa acactttatc acttaaattt aattctttta gacagtcttt aaccaatgta
     5941 acttggtctg ctgaatcata aattacaaaa cttctattgt aaccaatctt atttatatct
     6001 tttcttagta tacgaacaca gcaagaatgg aatgtactta tccacatatc cttagtttca
     6061 ggacctatat tttgttcaac tctctctctc atttcatttg cagctttgtt tgtaaatgtt
     6121 atagctaata tatttggtgc ttgtacacct ttatcttcta taagatatgc tattcttgtt
     6181 gttaatacct tagttttacc tgaaccagca ccagccagta taagtactgg accttcagtc
     6241 ttttctactg cttctctttg agcaggattt aatgtatcta aattcatatt tctcctcctg
     6301 ttaacagcca taaatatatt ttaatctaaa atatgaatta cttcaaatta taattatgta
     6361 ttatattaat agattatttc caatatatta caattaaata acatttttcc atataattta
     6421 tttcattgtt taataaaaaa aataacctta tgatttgggg aatcataagg cacctttaag
     6481 gggtctaggt taagggttat tatatataaa tctatttttt taaaataggt ttagggctta
     6541 attatttatt tgtattaagt tctctttcct tccaatactt atacaaatct tcttctttct
     6601 taaataaggg taaattcata tttctatgta cttttactaa ccatggggat tctaggccag
     6661 cttgtataat attattttca tttataaaca cattttctgc ttttccttca tcaatcaaaa
     6721 tccccttatc caatacatat atgtaatcac atatttcata cattaaattc atatcatgac
     6781 tggatattac tatttttata ttatttttat ttaatccctt tattatatct acaatagacc
     6841 tagtacttac tgggtctaaa ccagctgtag gttcatcaag taatacaatt tcattttcca
     6901 ttgctataac tgatgctatt gccactcttt ttttctgtcc atagctaaga aaatgtactg
     6961 gcctgtctat aaaatctatt ccattaacag ctactagagc tttgtttatt ctctctttaa
     7021 ttgttttttc atccatacca atgtttctca ttgcaaaggc tatatcatca tatacttttg
     7081 aataaaaaat ttgtttttct gggtcttgga agacaatacc tacatttttt ctaaggttgt
     7141 ataaacttct cttatcatat tttaactttt cttctttaaa aagaatttct ccagatgtag
     7201 gctttaatat acccattaaa ttcataaata atgttgattt tcctgaacca tttgaaccta
     7261 ttatacctat aacatttccc tttgaaaaat ccatattaat gtttaatagt gcattggtat
     7321 ttttttcata ttgatacgtt aaattattta ttttaaacat cattatcccc tactatgtga
     7381 aatttaccat catacaattt tatgtctaat gatatacaca tatcatcata ccttgtcata
     7441 agtcttttgt acagcatact tccaagaata cctaaggatt tatatgaagt ttttaaattt
     7501 atatatccaa atcttagctc ttgtgacttg tatatttctg aaaattcttc taaaaatatg
     7561 aatataaacc tatatattaa cattgataac tcgacaaaag tgtcaggtaa atgaagtttt
     7621 ttaaaaaaga atattaattg attaaaaggt gttgtaagta tacaaaaata cacacaagtc
     7681 aaacaagaca tcgctctaaa taacacatga atagacatgt caatagacgc ctttgatatt
     7741 cctacattaa aactaaaaaa ttcaaaacta tataataaat ctgctttatt aaaagatata
     7801 tttacaagag ttattcctat actaagaaat aaaaagtaca ttggtattct aagtaatttt
     7861 aaataatttt ttaaatctat tccagccaca caaacaacca aaatactcat taaaatcata
     7921 attccactta aaataaatat attttgtatt accatagaag caatcagaaa aattactcct
     7981 atggctactt ttttgtttgg atttacttta ctcaatctat ttgtatatgc atatttatca
     8041 attataagca tgattaactt ctctttcctt tttgaagacc taatatgtat cctattacac
     8101 cagcccctaa agctgcttgt gcagagaata ataaactttc tatttctcca cttggtggct
     8161 catatggact gctaaaccat ggtttgtaat ttggatttat cttagtaatt tcactttcag
     8221 cttgaccatc tgctcctcca tattcagcac ctgagttgac aagtaatggg aatataataa
     8281 gagctactac taataaaagt aataatatgt tagtttttgt tttagcactc attagcttta
     8341 actcctttat cattattttc tagtatgctt ttttctccgt tttctgtaat taaattatat
     8401 acaattacag taagtatacc ttctgctatt gctattggta tttgagtcat aaagaaaatt
     8461 cctaaaaatt taattgctga agccattacc ccacctgatg ggtctgggaa agccagtgct
     8521 aattgtattg aagttattgt atatgtggct aagtctccta ttgctgctgc aagaaatact
     8581 ggaatagcat tatttccatc ttttttcttt aaagccttaa atattaggaa tgatacgatt
     8641 ggccctatta tcgccattga aaaagcatta gctcctaaag tagttattcc tccatgtgct
     8701 aataacaatg cttggaatat taaaactata gttccaagaa caaacattac gcttggtcca
     8761 aacattattg ctccaagacc tacaccagta ggatgtgaac aacttcctgt tactgaaggt
     8821 atttttagtg ctgataatac aaacacaaat gctccacata aagctaataa tactttcttt
     8881 ttagggtctt gctttactat tttacctatt gattttaatc cgaataagaa aaatggtata
     8941 aatataactc cccatgctat agaccatttt actggtaagt aaccttccat tatatgcatt
     9001 gcatttgatg taactggagt taaaatgatt aacataagtg cagctataac ccctaattta
     9061 atattctgtt tcatcttagt atccctctct ccctttctaa taattaaaac ataataatac
     9121 atgtctgatt tatttaataa aataaaaaag cctaactcga tggttaggct tctaattttc
     9181 cacaatctaa atacaaacac ataaaacaaa catatctgta taattattat aagaaacttt
     9241 ctccatcccc gaagaaatta ctttaatatt ttaggcaggt ctcctgactt agcttcatcc
     9301 tactcctctt ccttcccatg agatataaaa aatatcatca tagtggctaa caaaagtttc
     9361 gtctgcatca cagtagcggg ggctgtaaag gaatttaacc tttttcccta ttaatcttgc
     9421 ttaaagaacc tataatatta tatatttaat ttttaaattc ttcttaaatt attttctata
     9481 taaatcattg tatacctttt ctgtgaaaat ttctacattt tttataaatt ttattcattt
     9541 ttatattttt atgtatataa attctttttt gtaagtttat taatttctaa ttatcttctt
     9601 taaatacatt gaaactacat cagaaaatct agttatatct cttgaatata taaaatcatt
     9661 tccatatatt aatctttcag cttcaagttc tgattctttt cctgtaaata ctcctaatac
     9721 taatatattt tgctttctag cttttctcac ttcattggct gtatctctca aaccaactat
     9781 acccctataa gccttttctc ctcttaatgt tctctcacta ctttttccta tctttacatc
     9841 atttggtctt ccatcgctga gaactatcag gattttattt tcttcatctc tatttattag
     9901 accactacat atagatttta ttgccaaacc atctctatta ttaccagcac aaaaatattc
     9961 aaatatattt tcactatttt ttatactatc atcataatct ttaaatcttt ttaatattgt
    10021 atagtctaaa aaactagaaa atcccatcac tctatttggt atgccaactt ctgttagagc
    10081 atttgcaatt atgtaagctt gaattgccac atttccctga tttctacttt gagagccact
    10141 tgcatccaat aatatatcaa taacgtattt ccctttttca ttttctatat ctttataaaa
    10201 tattttatta ttattacttc taccaactct ccaagctcta tttgctaata tagtaccaca
    10261 atcagaatat actctacttt tagcattttc ttctattaaa attcttgata gactttcttt
    10321 taatctcttt atttgctgtc tatacattct agcatgttct ctaaattttc ctaaattatt
    10381 ttctttttgt cttgttacat attttagttg aaatacatta ttacactcac ttctaagaac
    10441 tccatctgta aagtgtattc tacaaccttc atgaacattt ctacaatttt gtgtctcaat
    10501 ttttttaatt tcacctttac tcaaataagt ttttccataa taatgttcta tttttgaata
    10561 tatcttattt gcagtgtctt catcaacata tataactcgg tctgctgaat tgctacattt
    10621 agaatcatca aaatccccta caccttctac aagcatggat gaagatattg aatctatatc
    10681 actttcaata atattttctt cttcatcact ataaagttct tcatacatga aatcagcaaa
    10741 tgtatcaaaa tttacttcta cactttctac attattttca tcaataagac tattttcttc
    10801 tccatttaat atgtattcaa aataagttaa atatataaca tctaatgctt ttaaaatctc
    10861 cataatatct tgattggtat ctatatttct tatatcatta actattcttc tagtcatact
    10921 atctaatgct gggtgcttgt ccatactata aagtacaaat gtgtatttaa ttttatccat
    10981 aatattatca ttgtgtattt tggtaaaacg tgaaacaata tctttataag catttcttct
    11041 tatgtcttct atccctggcc tatctttaat gaccttttct tcaactattg tatttaatat
    11101 aacttgaatt agacccagta taatatcttt gttgtatcct tttcttattc tatttgtaag
    11161 atatttttta actatatccc aatctacata ctttcttcta gcacctgcaa ttattgcaaa
    11221 atatagacct atttcttttg aagagtaatc tttttctgat atatctatac tttcattgta
    11281 atcaccagct attgtccatg ataagttatt agctctattt tcaaattcat aatcatcata
    11341 tatccatttc ataatctcac ctatattaaa tatgacttat tggaaacaca tctatactct
    11401 cccatttatt aggtattcta gttttaatta catctccaac catttctttc tcatatacat
    11461 caaaagtctt tcctgtaagt cccatattaa ttgcaagagt tggttttaat cctcttctta
    11521 tagtcttaag agatgccata agaccacgta aatcaatagc tttactagat atctctccat
    11581 tttgagactt caattgtaaa tctaaaaata ttcctgcaaa gtgtattagt ttttcttcat
    11641 cagcatctga aaattcattt tttaaaatca tcattaactt atcttcttct ataggaggaa
    11701 tatctattac cataaatcta gataccagtg cttcattaag ttcttttgtt cctgcatatt
    11761 cataattcat agtcccaata aatcttgttg ctggatgtag attgactctc tcatacccag
    11821 gtacatcaat tattcttcta tagtctaaag ctgaatgtac cacaactata gcatcatttt
    11881 ttgccatatt aatttcatca aacaccccaa aacctccatt aatagcacac tcataaactg
    11941 agcctcttct aagtttaact tcattgtcta taaatgtatc tgtacctata agtgttgaac
    12001 tgtctgtatt tatatgaaat gatgtattcc actgaggtct attaaatatt tcccctagat
    12061 tatcagcaag taagtttttt cccgttgcct ttggtcccga taataatata ttttcttctt
    12121 ctaaaatagc tgctatacac atagacaaga tatctttacc ataaaaataa gttttagact
    12181 ttgttactct gtattctaaa tctttttcta atccataata atttctaaaa tacagtacat
    12241 cttcaataag tttttcatct accccttgca cccttagatt atctattata tccatatttt
    12301 tacccctttt atataaatag tatttgtttc atttcttatc accattttag cataaaagga
    12361 tataagctaa aattgatttt ttaatctccc cattttaagt aaaaccatgc accattttat
    12421 cactacaaaa ttaagagtac tacttactga tatttcttga ttttgttcgt ctatacgtat
    12481 ataatatatg ctgataaatt atgaggaaag gatgattgaa atatggaata tatgtcttgc
    12541 ccagaagtag caaaaaaatg gggtatttct gaaagaagag tacaaaaact atgtgaagaa
    12601 agtcgcatac caggagtttc aaaactcggg tatatgtggc tgataccaaa gaacgcagaa
    12661 aagcctgttg atggtagaac aaaaagaaga aaggaagtac aatatgaata gcgttttgat
    12721 tatagatgat gacaaagaac tttgtgctct tatgaaaaaa tgtgttgagc aagaaaattt
    12781 atctgctatt attgcacatt gtggtgcaga aggtctacat ttggtcgata aaaatagaca
    12841 cacactctct cttgtaattt tggacataat gatgccagat atagacggtt ttcaagttct
    12901 gaaaaaaatt agagaaacaa gtaatattcc agtaattatg cttactgcta aaaatgacga
    12961 ggatgataaa gtttccggac tacgtttagg tgctgacgat tacctaacaa aaccgttcag
    13021 cataaacgaa cttatggctc gtgtcaattc tcttattcgt cggtatacta tgttaaaccc
    13081 tgcttttata acagacacag attgcataat aataaatggc atgattattg acaagacaaa
    13141 ccgaattgtt tctgtcaata atattcctgt tcaacttaca agcaaagaat ttgatttact
    13201 tgcttttctg gcttctaata agggacaggt gtttaccaaa aaacagattt atacacaagt
    13261 atgggaagaa gaatatgctt ttgacgatag taacatcatg tctttcatca gtaaattgag
    13321 aaaaaagatt gaaccagacc ccaaccatcc attttatatt ttgacagttc gtggtgtcgg
    13381 ttatcgtttt aataaggagg cttaacatga atacaagtgt ctatctgctt ttgatattgg
    13441 ttcttagcct gattattata gcgtaccttg tttctgtcct gctacgtgtc cgaatacaac
    13501 ttacacttat aaaagatgct ttagaggata taaaaaatgg aaaccttaat cgacgtattt
    13561 taacagatga aaacgacatt acaaaacaaa tttgctatga tattaacgaa atagcaatca
    13621 atagccaatt tcaacttatt cagcaaaaac aatcagaaca agcctacaaa cagctaatga
    13681 caagtctctc ccatgatgta aaaactccac ttgcttcttt ggtcggttat ttggaagcag
    13741 tagaaagtaa aattgttgta ggagaggaaa aagacgagta tatccatgtt gcgtctaata
    13801 aggctcatta cttaaagaat tttgtagaaa atctatttga atgggtaaaa ttggattcta
    13861 aggaacaagt ttttcatttt gatatttttg acttgaatga attatcccgt aatattatat
    13921 ctgattggat acctgtttta gaaagcagtc attttgaata tgaatttgat ataccagaaa
    13981 tagagtactt cttacgtata gacgcaaatg catatacccg tatcattaat aacctattac
    14041 aaaatattat tacccatagt agtggcaaca aaatgacatt gagaattttt gaaaacaaag
    14101 agcaagctca aattataata acagataatg ggaaaggtat atcttcagac aatctcccac
    14161 atatttttga aaggttgtac caatgcgacc attcacgagc ttcaaaggga aatggtttag
    14221 gcttggcgat tgcaaaggaa cttattaacg ctcataaggg aaatattacc gccaacagca
    14281 ctcccggtat gggaacagaa tttacaatat tgcttcctaa agccctgtaa aagtacgagg
    14341 ctttcttact ctaaaacaag ataaaagcaa gattatggca aggttttggc aaggttcatg
    14401 ttttataatt ctaattgtag ttgattttga cgttgtatca actatctttt gtagaaacaa
    14461 atttattaaa agtgaggaaa ttatatatga atgattttgt gattgaaaca aagcaactta
    14521 caaaaattta tgggaatcaa acagtagttg acaaagtcaa tctccatgta aaaaaaggcc
    14581 gaatatatgg tctgttagga cgcaacggag ctgggaaaac cacaattatg aaaatgattt
    14641 taggattgac ttcaatcacg tatggcgagg tagatgtatt tggagagaat attaaggaac
    14701 gtgaaaaaca agtatatccc cgtatcggtg caattatcga aacgccagga ttttatccta
    14761 atctgacagg aacggagaac ttggagattt ttgcaaaact gcgtggtaca gccgccccta
    14821 attctgtaaa aagagcattg gaaattgtag gcttacctta taaaaataaa aagctgttta
    14881 gtaaatattc acttggcatg aaacagcgac ttggtattgc caacgctatc ctgcatgacc
    14941 cagaactgtt agttttagat gagccaacca atggtcttga ccctattggt attgcggaga
    15001 tgagaaagtt tattagggac ttgagcgttg agcatggaaa gacaattctt atttccagtc
    15061 atattctttc agaaatctca ttgttggctg atgatattgg aattatcgac cacggtgttc
    15121 ttttggaaga aagtagtatg agtgaactag aaaagaaaaa cagtaaatat atcctgctac
    15181 aagtttcaga tattccgaag acatcactta ttttagagcg tcaatttaac acgaaggatt
    15241 attccgttca agatgactac acgttacacc tttataacac taatctggat atgggtgaaa
    15301 tcaataaagc acttgtaatg cagaatgtaa ctgttattag ttctcaactt tgtaatgata
    15361 ctttagagga ctactttaaa aaaatcacag gaggagaggg cattgcttaa acttattcaa
    15421 acagaatttc ttaaactgcg tcgtaggaaa cttatttggc tgatgttgtt gtctgctctc
    15481 attatgccgt ttttcgcact actatacttc aattattttg gtaaaacagg tgttgagcca
    15541 ataaagtttt ataaatggtc tgcatttggt tatacacttt ggattatttt gcctgttgtt
    15601 ttgggtatat tttgcaccat gcttatacac gaagaaaacc agtatgatat gctcaaacag
    15661 ctttggattg tacctattag taaaatggga tactttttta gtaaattttt cgttgttttg
    15721 atttactcta tttgttttat gctgattaca gccgttgctt ctgtgttatt tagtgtactt
    15781 tctggatatg tcgtatttag ctgggcaagc attttatatt tgttgaaaaa atgtttagaa
    15841 attggtgtaa tcactgcttt tgtaatgttg ccgattttgg caatcgctac atctcaaaaa
    15901 ggatacattc tcccaatttg tatcacattg gtatatgcct tttccggttt tgttataatg
    15961 acaataaata tgtatttaca cccattatcc agtatgggag ttattatcat gagaaataaa
    16021 gacattccag gtcttatatt ttcacaggaa attaatgtcc cattagcatt tctttgtatt
    16081 tgtatttgga gtattgtatc agtattgttt gcaaatattg cactaggaag aagaaagtga
    16141 ggtgtagata atgtggaaat tactttgggc tgaatgtcaa aaaattcgtc gttcaaaaat
    16201 tgtttggatt acagtttttg catccattat gatagcagtc atagtttttg caggggggca
    16261 ggatgtatat aatgacccag atttacatta tggcttaaag agcgtttatg acggttcacg
    16321 gtatatagac aatgcaggtt ggtatatgga cgcagtacaa ccttggtcaa ctttttttgt
    16381 tcttcctgct gtcattgccc tattaggaag ctatattatt tgtcgtgaag aagaggagga
    16441 cactattaaa tccctgcgtc ttattcccat aaatgaaaca aatttaacca tagcaaaaat
    16501 gattattact tttatattca gtatacttct ttatttgtta ctctttacta taacattttt
    16561 gactgaatcc gttttacatt tttccgattt atcgacaaaa ttggttttaa gttgcatgaa
    16621 agagtatttt cttgatggca taggtgtatt ctttgcaatt tctcccatta ttgccttggt
    16681 atcgcgcatg aaaaaaggat attggcttgc attagtattc acagaagttt attctattgc
    16741 tggactattt gcgggtatgt caaatgtctt acaaaccttt tttcctattg cggcaatatt
    16801 taatatttct ggatactata taactactgg agaaaaaatt atggggagta tcataagttt
    16861 attactttgt gcctgccttt ctgcatttat acttaaaggg ctaaaacaca atgaaaaaaa
    16921 ttgaaatagg tatatcaaaa tgaaaaagat aaaaaaactg attattctaa ttgtattctt
    16981 gtttcttttt ggcatgttac actgttatac tgaatggaaa ttcaacaata acccacctaa
    17041 aggggtaata gaaagaataa atgagtggac tggattagta acttatgtta attatagtga
    17101 atgtaatatt agcaagttat tgtttcgtat tttaatacta taactttaaa tatttggttt
    17161 taatcttcca aacgaatata aaaaaactgt cacagaggca acatattttt gaatatttat
    17221 aaagtggtag ttttgatttt caaagctacc gccttttctt ctatataagc aaacttatcc
    17281 tcaacaaagt gtaaaacatg gtacatttta agaaaaaagt accacagaca caagcaataa
    17341 aagaaacgcc gagaacctac aaaaacgtag tgcttatgca gatttacgac gccttctatt
    17401 ttctcaaccg tcttaatgac cttgtacaaa agaaattttt ctaatatttt ttataatctt
    17461 atcttgtgat gttttttatg tataaatgac ttaataacaa atccaataaa aattatggat
    17521 attggtataa ttagaacgag gaatttataa tcattataat gtgacattat tcttacccaa
    17581 ctctcagaaa aaatatatcc tatactgatt aatgaagtat tccatatggt tattcccacg
    17641 atagatgata ttacaaaagt tataatattt tgccctgcta tacctgctat aaaagatatg
    17701 tatgttctac ataaagggat taatctacat acacaaacag aaatagaaga gtatttatta
    17761 aaataatctt gagatgcaaa tattcctttc tttgcctttg gacatatctc tattatttta
    17821 tttatgatag atttacctcc ccaatttccc actgtataac aaaatatcga accaagtata
    17881 cctgcaatta tacttaaaat taaaattgtc agaaatccaa aatgatttct tgcagcaatt
    17941 gctccacata aaggtaaaac aacttcgcta ggtaatggaa aacaagcata ctcaatcata
    18001 attaatacaa atacagagat taatccatat tgtaaaataa aactattgat tacagacact
    18061 tacttatcta tctcctttct tatttaaagg ttttaagggt acatgttcta aggattctca
    18121 ccctatattt aaagaatcaa tctctttaaa ctattatatg tatttacaca aagcatttat
    18181 aacatacttt aaaaatagta ccttaaaata agaaacttaa taaataaaaa aagattacgt
    18241 ggctacgtcc tactctccca ggcag
//
LOCUS       DAMKNB010000244        18160 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.guided.075, whole genome shotgun sequence.
ACCESSION   DAMKNB010000244 DAMKNB010000000
VERSION     DAMKNB010000244.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 18160)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18160)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18160
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.guided.075"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            <1..414
                     /locus_tag="PC494_003849"
     CDS             <1..414
                     /locus_tag="PC494_003849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF3914246.1"
                     /translation="RGFLAGGDDYITKPYSLKELELRIYARMRQYKNITSVPNVLKFS
                     ALVINVNSRKVTFDGESIDLTTMEFEILLFLAENKEQVFSKIEIYNQVWKMPDIGDQH
                     TVQVHIAQMRKKINSLSREHQYIQTVWGKGYKFVP"
     gene            486..2501
                     /locus_tag="PC494_003850"
     CDS             486..2501
                     /locus_tag="PC494_003850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HDF3914247.1"
                     /translation="MKKYNILKGTLIVLIVSLLAITGLNILYKYDNKYTYKSIRASNG
                     ILTIDNDTFTKGKLVFLIDDWEFYNHKIFKPNDFTEQDIKPEYVFIGQYPDFSMRKGN
                     QSPYGNATYRMRIKNEGKDKLLSLELPEIFSASEVWINGEMVSKLGDVGTEKYRPKIK
                     NSVVSFIAKKNTEIIINVSNFSHYYSGLYYPPALGETKDISNMMFYRLLFYSIICFTT
                     FAIAIFSLSVWFLSNKSKIYLYFGCMCVFFAIHVSYPFVHLLGLPLVSFTYAVEDLSY
                     FMVVLCIICINGSISKIEENKVYRFLILPLGITMSIISIVIPIILLPYDMYFVNIYGK
                     LIDIYKYIVFIYILMSSLVSIYKKTCSEHISSYILVSVNTVFGISILFDAVTSNRFEP
                     IFTGWQTEYCGFVIVILFSVMMINRNRIIIKENEKLTRNLEHEVEVRTNELTTLLNER
                     KRFLADVAHDLKAPVSAIQAFIDLIKVGNIHVDEETRTYLYAINQKSNEVQNRVRSLQ
                     EFTSQDKSIGISEKICLNNFIKEIYENNLPDTQACGVNFETYVLEKKIYAKINKEMLT
                     RAFENLIYNALTFTPFDGKIILSMDKEDGFAIIKISDNGKGIPPENIPKVFDRFFTER
                     DNNEPKGQGLGLYIVKSIIREHGGEIFVDSELGKGTVFTIKLSLCFL"
     gene            2551..3231
                     /locus_tag="PC494_003851"
     CDS             2551..3231
                     /locus_tag="PC494_003851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF3914248.1"
                     /translation="MQTKILIIDGDKDNCQKLKGFLEEKGISIDLAYNCEEAIGKIFS
                     NKYDLIFLEIILSDGDGWTLCKKIRNVTTCPIVYMTYINEDQSILNALNSGGDDYLIK
                     PLNLEILYAKVKAILRRMNSYVNNNENNTKLEEYNRTSGVIKLEDKIIKLTPTENKLL
                     NFFIENPEKTLTTKEIYEHVWMNEYLEDNYSVVVAVNGLRKKIEKDYKNPQKIITIRG
                     AGYYFNKE"
     gene            3612..4310
                     /gene="vanR"
                     /locus_tag="PC494_003852"
     CDS             3612..4310
                     /gene="vanR"
                     /locus_tag="PC494_003852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002594737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanR-ABDEGLN family response regulator
                     transcription factor"
                     /protein_id="HDF3914249.1"
                     /translation="MSGKILVVDDERDIADLIEVYLTNENYIVYKFYSGLDALNCINL
                     NEFDLAILDVMLPGVNGFSLCQKIREKYTYPIIMLTAKDEETDKITGLTLGADDYVTK
                     PFRPLELVARVKAQIRRYKKYSGNLQSGEELSHIFSFLGLELNTQTYECHLNGKALSL
                     TPTEFSILHVLLKNKGSVVNSENLFHVIWKDEYYNKSNNTITVHIRHLREKLGDTVDE
                     AKYIKTIWGVGYKI"
     gene            4346..5461
                     /locus_tag="PC494_003853"
     CDS             4346..5461
                     /locus_tag="PC494_003853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF3914250.1"
                     /translation="MKKINNFTYRKLRDKYKFIKREKNTEAYLKYKLYIMLAIYTGIV
                     LVLMFMADYTFSNFSNPLVKWLKLRRDVLFFLVFIIGYITIFNFYWKKPWNYLREIIN
                     ATHTIYQQNDELVELSKPLKEIEQQMNQIKMSVLLSQQAVKEAENKKNNLVMYLAHDI
                     RTPLTSVIGYLSLLKEIPNMDNSQKSKYTEVALDKAQYLEKLINELFEITRYNSNQIK
                     INFEKVDLYYMLLQLKDEFYPLLSEKGNRAILKANESLTIKADSEKLARVFNNILKNA
                     IAYSYPNTEIIISAVHKDSKVDIAFRNYGQTIPEEQLSAIFEKFNRLDEARKSDMGGA
                     GLGLSIAKEIINLHGGDITVQSKDEVTTFTISLPTST"
     gene            5606..6493
                     /locus_tag="PC494_003854"
     CDS             5606..6493
                     /locus_tag="PC494_003854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF3914251.1"
                     /translation="MELKIEHVTKKFKDKIAVEDVCLTLTPGVWGFLGANGAGKTTLM
                     RIITDIMKPTNGKILYNGKNIYTMGAEYRNLLGFLPQEFGFPQDFSVKDYLEYIAALK
                     DVPPREVKGKINNLLEILTLSDVKNKKIIKLSGGMKRRVGIAQAMLNDPKILIMDEPT
                     AGLDPGERVRFRNFISEFSHNRVVLISTHIVSDIEYISTQNAIMKSGKILDVGTTDKL
                     VKKVEGKVWECLISNRDISKYEMNLRIINQRSEKNNQVSIRYLAEKSQIDNSIAVEPR
                     LEDLYLWLFPEAVYSKEGK"
     gene            6494..7729
                     /locus_tag="PC494_003855"
     CDS             6494..7729
                     /locus_tag="PC494_003855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF3914252.1"
                     /translation="MRIFYLEIKRVLHSRRTLILLLLALVLSALMAFLPITYEGINYL
                     DDNGKVVELSGLDAIKYKKTIYANNSEISSGVVTPKKLKHALNIWKKTEEKYGKVGSE
                     DFPLDVYSKSILPIRPLLNRLPEAFANSETGFATELSEINTNDLDSFYEQCKTHLNDI
                     MKIERQTSSAQMKAQELYRKVDTPFEIYPGYSKDAFDYIIFYIFILLIICVAIAAPTF
                     SGEYQTQSDSILRCTKHGHIRLAFTKILALFSIFIIMFVICISIHLAISDLAFGTECL
                     KTSFQMLFSVISLVNINLLQAQILIAIGGLISILAMVSLTLFLSAKCKDSLTSMLIAF
                     SICLIPMGIGVSWIGYLLPPGGIGFKISLLYQMTSFNFLHLGGMSFWTPHIILFFSVI
                     EIPIFIFLAIRTYCKHQVS"
     gene            8110..9027
                     /gene="pstC"
                     /locus_tag="PC494_003856"
     CDS             8110..9027
                     /gene="pstC"
                     /locus_tag="PC494_003856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HDF3914253.1"
                     /translation="MIVKSRLVGLEKNDNNGNKTKYVIEKVAKNIFLLSALVAVASLL
                     LIIGFVFYKGLRPFIFEGYSFIDFLTGADWVPSANKFGISSMIVASIFATLGALVIGV
                     PVGILTSVFIAEVAPKRLAKIMSPAVELLAGIPSVLYGVFGLAVIVPTIQSIFNLPKG
                     QSLLAIVIVLAVMMLPTIISVSETAIRAVPKAYKEGSLALGASKIETIFKVVLPAAKS
                     GVLAAVVLGVGRALGETMAVILVAGNSPVMPTAITDSVRPLTTNIALEMGYAFGTHQE
                     MLFATGVVLFTFILILNLVLNKLSNKAVN"
     gene            9029..9853
                     /gene="pstA"
                     /locus_tag="PC494_003857"
     CDS             9029..9853
                     /gene="pstA"
                     /locus_tag="PC494_003857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003460575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HDF3914254.1"
                     /translation="MRKFKENLLKSLVYLSALFTIVSLVVIVGFIFIKGIGNMNFNFL
                     FSNYSASGDGGILPMIITTLYTVVVSIVVATPIGILAAIYLQEYAKKGKAVTAIRFAT
                     ESLSGIPSIVYGLFGGIFFVVTLKMGYSIVAGSLTVAIIILPVIIRTTEEALKTVPQA
                     YRESSLALGATKFQTLYKVVLPSAIPGILSGVILSVGRIIGESAAILLTAGTVAKMPG
                     GIFDSARTLTVHSYLLTKESGDIATAASIGIVLIVIVLALNMLARFVAKKLNKANY"
     gene            9872..10636
                     /gene="pstB"
                     /locus_tag="PC494_003858"
     CDS             9872..10636
                     /gene="pstB"
                     /locus_tag="PC494_003858"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HDF3914255.1"
                     /translation="MELIDKIKMSVKDLDLFYGDKQALKKINMDIKENKVTALIGPSG
                     CGKSTFIRTLNRMNDLIEDVTIKGNISVDGEDIYTSDDVINLRTKVGMVFQKPNPFPM
                     SIYDNVAYGPRTHGLRDKKQLDKIVEESLKGAAIWDEVKDRLKSSALGLSGGQQQRIC
                     IARAIAMRPEVILMDEPTSALDPISTLKVEELIEDLKKDYTIVIVTHNMQQAARISDE
                     TAFFLNGEVIEFSDTKTMFTTPVDKRTEDYITGRFG"
     gene            10664..11317
                     /gene="phoU"
                     /locus_tag="PC494_003859"
     CDS             10664..11317
                     /gene="phoU"
                     /locus_tag="PC494_003859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HDF3914256.1"
                     /translation="MVNNSLDISIDTLKEQTVLMMEKCEEAIEKSVTCMIEKDLEGAR
                     KVVEDDEEINKLREEIRDKSIELIVLKQPMARDLRFIYSLGNISIELERIGDYAANIA
                     REMLKIGGEAYIKELIDIPKMAKECKSMMSQTREALILFDASIAYDVGTKDDIVDGLY
                     EQVQIDCLKIMHENSNTIDQGVKLLLIGRYLERIGDHITNVCEKIIFAIEGKMVEIG"
     gene            11475..12344
                     /locus_tag="PC494_003860"
     CDS             11475..12344
                     /locus_tag="PC494_003860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HDF3914257.1"
                     /translation="MKLQKMGMRTIKTGISVTLCMILGDYLVENMFYSLVACIISVQD
                     TVKGSLKTGINRVEGTILGGIIGFIFAIIKAGDPFLCGLGVMCSIYLCNLFKIKSVVV
                     ACVTFLAIHLGVGNSDPVYYSLHRVLDTSVGVLFGVLVNYYVARPNYLNSVIDEFKKI
                     EELSMLLIEDKILRKENLNVEKFEEEVEKLEEIYSKLIDELDYSLSETNIEKIENALR
                     ICREIHFHMQSIELLENKLYLKEHTYKYLKKTYNVDKLDWNIDEEKSPVFNYHLMKIM
                     IEIELLRKLNKSY"
     gene            12431..13867
                     /locus_tag="PC494_003861"
     CDS             12431..13867
                     /locus_tag="PC494_003861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron hydrogenase"
                     /protein_id="HDF3914258.1"
                     /translation="MNTRNDNSKILEIYKMKLFGELVKAVWNDDIEDIENLPNKILNE
                     DLKDNLNNYFSGKFDKDTMVNLIRVTMGLDVTEDTDKNLKESLHEAVNLDEVKRPIIS
                     VISDACKYCDENNKEDESCKIRSKHINCNEEDVCSACGDCVSRCKLGAISDKIEFIPM
                     IKLLKDIKSPVYAIVAPAFVGQFGKDVSPGKLRTALKKIGFEDMIEVALAADMLTAKE
                     AYDYYEHMKKDEEGCFITSCCCPIWVSLIQNSFPQILENVSPSVSPMIACGRAVKILN
                     PDAKVVFIGPCMAKKKEAMLEDIKDAVDFVLTFKELQEIFDALELNPAIMDESNRVEA
                     SLSGRVYARTGGVSKAVKLSVRRIDKNIKFEEKAFEGTKECMDGLKKVLNKEIEATFI
                     EGMGCVGGCVGGPKRILSVEEGTKNVDEYSESTNMETPFDNLNVLQFLTSLGIKRVES
                     LGEKEEEKVKKIFSRDIKSNKKENKYKK"
     gene            13915..14742
                     /locus_tag="PC494_003862"
     CDS             13915..14742
                     /locus_tag="PC494_003862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HDF3914259.1"
                     /translation="MKIKDNKAVFHVFIRIFLIAVLILTGTLLEEKINNVPVENISSK
                     GENTLELLSQSNTLGEIIYKASQEETKGPGATSEKVAYITIDDGPSKYTNALLDILKE
                     NDVKATFFMLNQNMKNHKEEVRRVLEEENSIGFHSVSHDIHKLYKSPEVTVGEFNTCN
                     NTLQEITGQSSKLIRLPYGSKPYMPEGSYNKLMANDYLIWDWNLDTQDWKSSTSQIVS
                     NILYYGRKRDELVVLIHEKEQSLNALNNIIRILKERGYTILPITENITPKNFWQENL"
     misc_binding    15043..15305
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            15381..18047
                     /locus_tag="PC494_003863"
     CDS             15381..18047
                     /locus_tag="PC494_003863"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HDF3914260.1"
                     /translation="MENTNLSKTYNPKDFEARLYKKWMDEGYFKSKPNPDKKPFTIMM
                     PPPNITGQLHMGHALDHTLQDILIRWKRMDGYEAFWLPGTDHASIATEVKVVERIKKQ
                     EGKTKYEIGREEFLKRAWEWKDEFGGKISNQLKQLGDSCDWDKERFTMDEGCNEAVIE
                     FFVSLYEKGHIYRGNRIINWCPDCKTTLSDAEVEHEEHDGNFYHIKYPLKDSEDFLEI
                     ATTRPETMIGDTGIAVNPEDDRYKHLIGKTAILPLVGRELPIVADSYVDLEFGTGAVK
                     MTPAHDPNDFEVGLRHNLEQLNTMNEDGTMNEVCGKYEGMDRFECRKAIVADLKEQGY
                     LIKIKEHNHNVGTCYRCHTVVEPRLSEQWFVKMEELAKPAIDILKKGELEFVPDKFDK
                     TYLQWLENIRDWCISRQLWWGHQIPAYYCQECGEIVVARKMPDKCPKCGSTHFKQDED
                     ALDTWFSSALWPFSTLGWPNKTEALDYYYPTSVLVTGYDIIFFWVVRMAFAGMFCMNE
                     KPFDHVLVHGLVRDSQGRKMSKSLGNGIDPLEIIEQYGADALRFTLTTGNSPGNDMRF
                     YMERVEFARNFANKLWNASRFVFMNIDEDIIKNMTRESVKEDLTLADKWIISRANNIV
                     KEATNNMDKFDLGIALQKIYDFTWSEYCDWYIEMVKPRLYGEDANAKSAALYTLTYVL
                     EKILKLLHPYMPFITEEIYTHLPTVEGCIIVSEWPKYNEEDNMAEEEDMMNLLMEGIR
                     SIRNVRAEMNVPPSKKAKLIIIPSEEKIEAIELGKDYFITLASASNVEIAKDKSNVPE
                     DAVGVVIDGVEIFIPLNELVDFEKEIERLSKEKKKLEGEIKRVNGKLANQGFLAKAPE
                     SLIEEEKAKKEKFEEMIKSVEERLTNLESKIK"
BASE COUNT         7134 a         1976 c         3279 g         5771 t
ORIGIN      
        1 cggggatttt tagctggggg ggatgattat ataacaaaac cttatagttt aaaagaactt
       61 gaacttagaa tatatgctcg tatgaggcag tacaaaaata ttacatcagt tcctaatgtg
      121 ttaaagtttt cagcgttagt aataaatgta aattcaagaa aagtaacttt tgatggagaa
      181 agtatagatt taactactat ggaatttgaa atattattgt ttctagctga gaacaaagaa
      241 caagtatttt caaagataga gatatataac caagtttgga aaatgcctga tattggagat
      301 caacatacag tgcaggttca tattgcacag atgagaaaaa aaattaattc tttaagcagg
      361 gagcatcaat acattcaaac cgtatgggga aaaggatata agtttgtacc ataagtgaga
      421 tactgtaatt aataaatagt tcttgtttta tttaatacga ctatgaaaga gatgtggttg
      481 atgcaatgaa aaagtataat atactaaaag gaactctcat tgtattgata gtctctctgt
      541 tggcaataac aggattaaat attctgtata aatatgataa taaatataca tataagtcta
      601 ttagagcaag taatggaatt ttaactatag ataatgatac tttcactaaa gggaaacttg
      661 tctttttgat agatgactgg gagttttata atcataaaat atttaaaccg aatgatttta
      721 cagagcaaga tataaaacca gaatatgttt ttataggtca atatccagat ttttctatga
      781 gaaaagggaa tcagtcacca tatgggaatg ctacttatcg tatgagaata aaaaatgaag
      841 gcaaggataa gctactaagt ttagagcttc ctgagatttt ttccgcaagt gaagtatgga
      901 taaatggaga aatggtttct aaattaggag atgtaggaac agaaaaatat agacccaaaa
      961 ttaaaaattc agtagtaagt tttattgcaa agaaaaatac agaaattata atcaatgtat
     1021 cgaatttttc acattattat agtggtttgt attatccgcc tgcattagga gaaacaaagg
     1081 acataagtaa tatgatgttt tatcgattac ttttttatag tataatttgc ttcacaactt
     1141 ttgcaatagc tatattttca ttgtccgtat ggtttctttc aaacaaaagt aaaatttact
     1201 tatattttgg atgtatgtgt gttttctttg ccatccatgt atcctatccc tttgtacatt
     1261 tgttaggact gcctttggta agctttacat atgcggttga agatttgtca tattttatgg
     1321 tagttttatg tattatttgt ataaatggaa gtatatccaa aatagaagaa aataaagtgt
     1381 acagattttt aattttacca ttaggaatta caatgagtat catatctata gtgataccaa
     1441 ttattcttct tccatatgat atgtactttg tcaacatata tgggaagtta atagacatat
     1501 ataaatatat tgtatttata tatatattaa tgtcttcgct ggtttcaata tataaaaaga
     1561 catgctctga gcatataagt tcttatattt tagtttcagt aaacactgtt tttggaatta
     1621 gcatattatt tgatgcagtt acgagtaata gatttgagcc tatatttaca gggtggcaaa
     1681 cagaatattg tgggtttgta attgttattt tattttctgt tatgatgata aacaggaata
     1741 gaataataat aaaagagaat gaaaaactta caaggaatct tgaacatgaa gttgaagtga
     1801 gaactaatga acttacaaca ttgttaaatg aacgtaaaag attcttggca gatgtagcac
     1861 atgatttaaa ggcacctgtt tcggctatac aagcatttat agatttgata aaggttggta
     1921 atattcatgt agatgaagag acaagaacct atctttatgc tataaatcaa aagtcaaatg
     1981 aagtacaaaa tagagtacgt agtttgcaag aatttacatc acaagataaa agcattggta
     2041 ttagtgaaaa aatatgtctg aataatttta ttaaagagat atatgaaaat aatttgccag
     2101 atacacaagc atgtggtgta aactttgaaa cttacgtatt ggagaaaaaa atatatgcaa
     2161 agataaataa agagatgctt acaagagcat ttgagaattt aatttataat gctttgacct
     2221 ttactccatt tgatggaaag ataattttat caatggataa agaagatgga tttgcaatta
     2281 ttaaaatttc tgacaatgga aaaggtatac ctccagaaaa tataccaaag gtatttgaca
     2341 gattctttac agaaagagac aataatgagc caaaagggca agggttaggg ctatatattg
     2401 tcaaatccat tataagagag catggtggag aaatatttgt agattcagaa ctaggaaaag
     2461 gaactgtttt tacaataaaa ttaagtctat gttttttata ataatagctt atttaatata
     2521 aaagaataat gatatttggg agtgattata atgcaaacta agatattgat aatagatgga
     2581 gacaaggata attgccagaa gctaaaagga tttctggagg aaaaaggaat aagtatagat
     2641 ttagcatata attgtgaaga agctattgga aaaatattta gcaataaata tgatttaata
     2701 tttttagaaa taattctaag tgatggtgat ggatggactc tttgtaaaaa aattagaaat
     2761 gtaactactt gtccaattgt ttatatgact tatataaatg aagaccaaag cattttaaat
     2821 gctttaaatt ctggtggaga cgattactta ataaagcctc taaatttaga aatattatat
     2881 gcaaaagtaa aagctatttt aagaagaatg aactcatatg taaataataa tgaaaataat
     2941 acaaaattag aggaatataa tagaactagt ggagtaataa agttagaaga taaaataata
     3001 aaattgactc caacagaaaa taagttgtta aactttttta tagagaatcc tgaaaagact
     3061 ttgactacta aagagatata tgaacatgta tggatgaatg aatacttaga ggataactat
     3121 agtgtggtag ttgcagtgaa tggattaaga aagaaaatag agaaagatta taaaaatcct
     3181 cagaaaatta taacaataag aggagcagga tattatttta ataaggaata ataaatatat
     3241 taatatcatt aataattgtt ataaatgtga aatgctaacg atatctaaac taaattatta
     3301 taaaatagct gactgtaatt taattgataa agcctattct tctagacttt gccagttaaa
     3361 ttacagtcag ttttattata taaaaaaatg cgtaacagaa ctattatttt atagattata
     3421 tttgaaaaga taaataaatt gtatatctaa atttatatat tattttttac ctttaatata
     3481 tattaaataa taaaatagtt aaataataag attaagaatt tcttaataaa ttctaatgta
     3541 aaaaattata taaaaaaaat taaatttagt ataatatata taaatatata tagaaaggat
     3601 gtttaaagtc tatgagtgga aaaattttag ttgtagatga cgaacgtgat atagctgatt
     3661 taatagaagt ctaccttaca aatgaaaact atattgttta taaattttat tctggtcttg
     3721 atgcactaaa ctgcattaat ttaaatgaat ttgaccttgc aattttagat gttatgttgc
     3781 caggagtaaa tggattttct ttgtgccaaa aaatccgaga aaaatatacc tatccaatca
     3841 ttatgttaac agctaaggat gaagaaacag acaagattac aggcttaact ttaggtgcag
     3901 atgattatgt tactaaacct ttccgacctt tggaacttgt tgctagagtg aaggcacaga
     3961 ttagaagata taagaaatac agtggaaatt tacaatctgg tgaagaactt tcacatattt
     4021 tttctttttt aggtctggaa ttgaataccc aaacatatga atgccattta aatggtaaag
     4081 ctctttcact tactccaaca gagttttcta ttctacatgt attattgaaa aataaaggct
     4141 ctgtggtaaa ttcagaaaat ctttttcatg ttatctggaa agatgaatat tacaataaaa
     4201 gtaacaatac tataacagtt catattcgcc atcttcgtga aaaattaggt gatactgtag
     4261 atgaagcaaa atatataaaa acaatttggg gtgttggtta caagatttga cacatatttt
     4321 tcttgtcaag aagggatgta gtattatgaa aaagattaat aattttactt ataggaagct
     4381 aagagataaa tataaattta taaaaagaga aaaaaataca gaggcgtatt taaagtataa
     4441 attatatata atgttagcta tctatacagg tatagtattg gttttaatgt ttatggctga
     4501 ttatacgttt tcaaattttt caaatcctct tgttaaatgg cttaagttga gaagagatgt
     4561 attatttttt ttggttttta taattggata tatcactatt ttcaattttt attggaaaaa
     4621 accatggaat tatttaagag aaatcatcaa tgcaacacat actatttatc aacaaaatga
     4681 tgaattggtt gaactatcta agccattaaa agaaatagag caacaaatga accaaattaa
     4741 gatgtctgtt ttgttaagtc aacaagcagt gaaagaggct gaaaataaaa agaataacct
     4801 tgtgatgtat ctagcacatg atataaggac accacttact tcagttattg ggtatttgag
     4861 cttattaaaa gaaataccta atatggataa ttctcaaaaa tctaagtata ctgaagttgc
     4921 acttgacaaa gcacaatatt tagaaaaact tatcaatgaa ctttttgaaa taacacgata
     4981 taattctaat caaatcaaaa ttaatttcga aaaagtagac ctatattata tgttacttca
     5041 gttaaaggat gaattttacc cattgctatc tgaaaaagga aatagagcca ttctaaaagc
     5101 aaatgaaagt ttaacaataa aagcagattc tgaaaaactt gcaagagtat ttaataatat
     5161 cttgaaaaat gctattgctt acagttatcc taatacagaa attattatct cagcggttca
     5221 taaagacagc aaggtagata ttgcttttag aaattatgga cagacaattc cggaagaaca
     5281 actttctgct atatttgaaa agttcaatcg tttagatgaa gctagaaaat ctgatatggg
     5341 tggtgcaggt ttagggcttt ctatagctaa ggaaattata aatttgcatg gtggtgatat
     5401 tactgttcaa agtaaagatg aagtcacaac atttaccata tcgcttccta catctactta
     5461 gtaaaatata aatcaaatat taggattttc ttaagaaatt atctatttaa tattaaaact
     5521 atgagtgtct ttgtttagta aaataaatac tgagcaaggc acttttgttt ttgcaggtaa
     5581 gtagataaag agaggagttt caaatatgga attaaaaatt gaacatgtga caaaaaaatt
     5641 taaggataaa attgctgtag aagatgtttg ccttacttta acaccaggtg tgtggggatt
     5701 tctaggagcg aacggagcag gtaaaactac ccttatgaga attattacag atattatgaa
     5761 acctaccaat ggcaaaattc tgtataatgg aaaaaatatt tatacaatgg gtgctgagta
     5821 cagaaattta ctgggatttt taccacaaga atttggtttc ccacaggatt tttctgtaaa
     5881 agattattta gaatatatag cagcattgaa agatgtacca ccaagagaag taaaaggaaa
     5941 aattaataat ctattggaaa tccttacatt atctgatgta aaaaataaaa agattattaa
     6001 attatctggt ggaatgaaac gacgagtggg aattgcacaa gccatgttaa atgaccctaa
     6061 aatccttata atggatgaac caacagcagg gcttgaccct ggtgagcgag tgagatttcg
     6121 taattttatt tcagaatttt ctcataatcg tgttgtccta atatctactc acattgtatc
     6181 tgatattgag tacatatcaa ctcaaaatgc tattatgaaa agtggaaaaa ttcttgatgt
     6241 gggaacaacc gataaactgg ttaagaaagt agagggcaaa gtatgggaat gtcttatatc
     6301 aaatagagat atttcaaaat atgaaatgaa tttacgtata atcaatcagc gtagtgaaaa
     6361 aaacaatcaa gtatctattc gttacttggc agaaaagtca caaattgata actctattgc
     6421 tgttgaacca cgactagaag atttatattt atggttattt ccagaagcag tttatagtaa
     6481 ggaggggaaa taaatgcgta ttttttattt ggaaattaaa cgagtgttgc actcacgtcg
     6541 tacattaatt ttattattgt tggcgttggt tttatctgca ttgatggctt ttcttccaat
     6601 tacttatgag ggtatcaatt atttagatga taatggcaag gtagttgaat tgagtggttt
     6661 agatgctatt aaatataaaa aaacaattta tgctaataat agtgaaatta gtagtggagt
     6721 tgtaacacca aaaaaattaa agcatgcttt aaatatatgg aaaaaaacag aagaaaagta
     6781 tggtaaagta ggtagtgaag attttccact agatgtttat tctaaaagta ttttaccaat
     6841 acgcccattg ttgaatagac ttcctgaagc atttgctaat tcagaaacag gatttgcaac
     6901 agaattatca gaaataaata caaatgattt agattctttt tatgaacaat gcaaaactca
     6961 tttaaatgat attatgaaga ttgaacgaca aacttccagt gcacaaatga aagcacaaga
     7021 actttataga aaagtagata ctccatttga gatataccca ggttattcta aagatgcttt
     7081 cgattatata atattttata tttttatatt attaattata tgtgttgcaa ttgctgcacc
     7141 tactttttct ggtgagtatc agacacaatc agatagcatc cttcgttgta cgaaacatgg
     7201 acatattcgt ctagcgttta ctaaaatatt agctctattt tctatattta taataatgtt
     7261 tgttatatgt atttctatcc atttggcaat ttctgattta gcttttggta ctgaatgctt
     7321 gaaaacctca tttcaaatgt tgttttctgt aattagtcta gtaaatataa atttactaca
     7381 agcacagatt cttatagcta ttggtggtct aatttcaata cttgcaatgg ttagtttaac
     7441 attattttta tctgcaaaat gtaaggattc tcttacttct atgctgattg ctttttctat
     7501 ttgcttaatt cctatgggaa taggtgttag ttggattgga tacctattac cgccaggggg
     7561 aattggtttt aagattagtt tattatatca aatgacatca tttaatttct tacacttagg
     7621 aggtatgagt ttttggacac cacacattat actgtttttc tcagttatag aaatacctat
     7681 ttttatattt ttggctattc gtacctattg caaacatcaa gtatcgtaac aatttgatgg
     7741 aaataatagt gatataaact agaggataca ataattatat atgtagtata aaagttaaat
     7801 ttagttaaca aatcttaata gcagatatag gtaataaatt atacataaac tgtattatta
     7861 cctatatctg ctattttaat atagagaaac aacagtatat tgtaaagtaa atgtcaaata
     7921 tagttttaaa agtaaaatta atgttaaaaa gtaaatataa ttttacactt gcttaactta
     7981 atcctaatat agatttaact taaaaaaagt agaataaaag tataggaaat ttgatgaaga
     8041 cgaattataa aaaattaaat tttgaataca gaacgaaaat tgataagtat attttaatgg
     8101 gagggtatta tgatagtaaa atctagatta gtaggtttag aaaaaaatga caataatggc
     8161 aataagacaa aatacgtaat tgaaaaagta gcaaaaaata tttttctact tagtgcttta
     8221 gtagcagttg caagtttact tttgataata ggattcgtat tttataaagg attaagacca
     8281 tttatatttg aaggatattc atttatagac tttttaactg gtgcagattg ggttccttct
     8341 gccaataaat ttggaatatc atctatgata gtagcatcaa tatttgcaac acttggagca
     8401 cttgttatag gagtacctgt tggtatatta acctctgtat ttatagcaga agtagcacct
     8461 aaaagattag caaaaataat gtcaccagca gttgaacttt tagcaggtat accttcagta
     8521 ttatatggtg tatttggtct tgcagtgata gttccaacta tacaaagtat atttaatctt
     8581 ccaaaaggtc aaagtttgtt agcaatagta atagtattag cagtaatgat gttaccaaca
     8641 ataatatctg tatcagaaac agcaataaga gcagtaccaa aagcatacaa agaaggttca
     8701 ttagcacttg gtgcatcaaa aatagaaaca atattcaaag ttgtattacc tgctgcaaaa
     8761 tctggagtat tagccgcagt agtgttagga gtaggaagag ctttaggtga aacaatggca
     8821 gtaatacttg ttgcaggcaa ctcaccagtt atgccaactg caataacaga tagtgtaaga
     8881 ccacttacaa ctaatatagc acttgaaatg ggatacgcat ttggtacaca tcaagaaatg
     8941 ctatttgcaa ctggagtagt attgtttaca tttatattaa ttttaaactt agttttaaat
     9001 aaactttcaa ataaggcggt aaattaagat gagaaagttc aaagagaatc tattgaagtc
     9061 attagtatat ctatcagcac tatttacaat agtatcatta gtagttatag tgggatttat
     9121 atttataaag ggaattggca acatgaattt taatttctta tttagcaatt attcagcatc
     9181 aggtgatggt ggtatacttc caatgataat tacaacatta tatacagtag tagtttctat
     9241 agttgtagca actcctatag gaatattggc tgctatatat ttacaagaat atgctaaaaa
     9301 aggaaaagca gttacagcta taagatttgc aactgaaagt ttatcaggga taccatctat
     9361 agtatatgga ttatttggag gaattttctt tgtagttaca ttaaaaatgg gatattccat
     9421 agttgcaggt tcacttacag ttgcaataat aatattacca gtaataatcc gtacaacaga
     9481 agaagcttta aaaacagttc ctcaagctta tagagaatca tcattggcat taggagctac
     9541 aaaatttcaa actttatata aggtagtact tccaagtgca ataccaggaa ttttatctgg
     9601 agtaatctta tcagttggtc gtataattgg agaatcagct gcaatattac ttacagcagg
     9661 tactgtagcc aagatgccag gtggaatatt tgatagtgca agaacattaa ctgtacactc
     9721 atacttactg actaaagaga gtggagatat agcaacagca gccagtatag gaattgtttt
     9781 aatagtaatt gtgttagcac taaacatgct agcaagattt gttgctaaga aattaaataa
     9841 agctaattat taaatttaag aggtgtgaat aatggaatta atcgataaga taaaaatgag
     9901 tgtaaaagat ttggatttat tttatggtga taagcaagca ttaaagaaaa taaatatgga
     9961 tataaaagag aataaggtta ctgctttaat aggtccatct ggatgcggaa aatcaacttt
    10021 tataagaacg ttaaatagaa tgaatgactt aatcgaagat gtaacaatta aaggaaacat
    10081 ttctgttgat ggagaggaca tatatacctc agatgatgtt ataaatcttc gtactaaagt
    10141 aggaatggta tttcaaaagc caaatccatt tcctatgagt atatatgata atgtggcata
    10201 tggtcctcgt acacatggac taagagataa gaagcaatta gataaaattg tagaagaaag
    10261 cttaaaaggt gcagctattt gggatgaggt taaagacagg cttaaatcat ctgcactagg
    10321 actttctggt ggtcaacaac agcgtatatg tatagcaaga gcaattgcta tgagaccaga
    10381 agttattctt atggatgaac ctacatctgc tttagaccca atttcaacat taaaagtaga
    10441 ggaacttata gaggatttaa aaaaagacta cacaatagtc atagttacac ataatatgca
    10501 acaagctgct cgtatatcag atgaaacagc ttttttctta aatggagagg ttatagaatt
    10561 tagcgataca aaaactatgt ttaccactcc tgtagataaa agaacagaag actatataac
    10621 aggtagattt ggttaaaata tataactata aaggagttag acaatggtca ataatagttt
    10681 agatataagt attgatactt taaaagaaca aacagtgctt atgatggaaa aatgtgaaga
    10741 agcaatagaa aagtctgtga cttgtatgat agagaaggat ttagagggtg caagaaaagt
    10801 agtagaagat gatgaagaaa taaataaatt aagagaagaa ataagagata agagtataga
    10861 gctaatagta ttaaagcaac caatggcaag ggacttaaga tttatttatt cattaggtaa
    10921 tatatctata gagctggaaa gaataggaga ttatgcagca aatatagcta gagaaatgct
    10981 gaagataggt ggagaggctt atataaaaga gctaatagat attcctaaga tggcaaaaga
    11041 atgtaagtct atgatgtctc agactagaga agctttaatc ttatttgatg caagtatagc
    11101 ttatgatgtt ggaactaaag atgatattgt agatggattg tatgaacaag tacaaattga
    11161 ttgtttaaaa ataatgcatg aaaactcaaa taccatagac caaggggtaa aacttctact
    11221 tataggaaga taccttgaaa gaattggaga ccatataaca aatgtatgtg agaagataat
    11281 ttttgcaatt gagggtaaaa tggttgagat aggataaaaa actgctttaa agcagttttt
    11341 ttattgtcta aattaagaaa gaattgataa aaaaatatga ttaatgggta aatttaaaaa
    11401 attgtgatat actaggaaca tattaaatat gaggatgcgt attttatata aggtgctttt
    11461 taggaggtgg aactttgaaa cttcaaaaga tgggtatgag gactataaaa acaggaatta
    11521 gtgtcacttt atgtatgatt cttggtgact atttagtaga gaatatgttt tattctctgg
    11581 tagcatgtat aatttctgtt caagatacag taaaaggttc tttaaagacg ggaatcaata
    11641 gagtggaagg tactatttta ggtggtataa taggattcat atttgccatc attaaagctg
    11701 gagacccatt tttatgtggt ctaggagtaa tgtgctcaat atatttatgc aatctgttta
    11761 aaataaagtc agtagtagtt gcctgtgtaa cctttctggc tatacatcta ggtgtaggaa
    11821 atagtgaccc tgtgtattat tctttacata gggtgttaga tacatctgtg ggtgttttgt
    11881 ttggagtact tgttaattat tatgttgcta gaccaaatta tctaaatagt gttatagatg
    11941 agtttaaaaa gatagaagaa ctttcaatgt tgcttatcga agataaaatt cttagaaaag
    12001 aaaatttaaa tgtagagaaa tttgaagaag aagtagaaaa attagaagaa atatattcaa
    12061 aacttattga tgagttggat tatagtttga gtgaaactaa tatagaaaaa attgagaatg
    12121 ccttaaggat atgtagagaa atacattttc atatgcagtc tatagagtta cttgaaaata
    12181 aactttattt gaaagagcat acatataaat accttaagaa aacatataat gtggataagc
    12241 tagactggaa tatagatgaa gaaaaaagcc ctgtattcaa ctatcatcta atgaaaataa
    12301 tgattgaaat agagttgttg agaaagctaa ataaatcata ttaataatag tagttaaata
    12361 ataaataaaa aatagtatct ttgtaaatat taaacatata taagtttaat ttatggaggt
    12421 actatttttt atgaatacta gaaatgacaa ttctaaaata ctagaaatat ataaaatgaa
    12481 gctttttggc gaacttgtaa aagcagtgtg gaatgatgat atagaggata ttgaaaactt
    12541 acctaataaa attttaaatg aagatttaaa ggataattta aataattatt ttagtggaaa
    12601 atttgataaa gatactatgg taaatttaat tagggtaact atgggattgg atgtgacaga
    12661 agatacagat aaaaatttaa aagagtcact acatgaagct gtaaatttag atgaagtcaa
    12721 aagaccaata atatctgtaa tatcagatgc ttgcaaatat tgtgatgaaa ataataagga
    12781 agatgagtca tgtaagataa gaagtaagca tattaattgt aatgaggaag atgtatgtag
    12841 tgcttgtggt gattgtgtat caagatgtaa gttgggtgca atttcagata aaatagaatt
    12901 tataccaatg ataaaattgt taaaagatat aaagagccct gtatatgcaa tagttgcacc
    12961 agcttttgta ggacagtttg ggaaagatgt aagccctggt aaattaagaa ctgcattaaa
    13021 aaagatagga tttgaagata tgatagaagt tgctttggca gcagatatgc ttactgcaaa
    13081 agaagcatat gattattatg agcatatgaa aaaggacgaa gaaggatgct ttataactag
    13141 ttgttgctgt cctatttggg ttagtttgat acaaaatagt tttcctcaga tattggaaaa
    13201 tgtatcacca tccgtttctc ctatgattgc ttgtgggaga gctgtaaaaa ttttaaatcc
    13261 agatgctaaa gttgtattca taggtccttg tatggcaaaa aagaaagaag caatgttaga
    13321 agatataaaa gatgcagttg attttgtgct tacatttaaa gagttgcaag aaatatttga
    13381 tgcattagag ttaaatccag caataatgga tgagagtaat agagtagagg cgtccctttc
    13441 aggtagagtt tatgctagaa caggaggtgt aagtaaagca gttaagttat cagttagaag
    13501 aattgacaaa aatataaaat ttgaagaaaa ggcatttgaa ggaacaaaag agtgcatgga
    13561 cggtctaaag aaagttctaa ataaagaaat agaagctaca tttatagaag gaatggggtg
    13621 tgtaggaggc tgtgtaggag gtccgaagcg tattttaagt gtggaagaag gtactaagaa
    13681 tgttgatgaa tatagtgaaa gtacgaatat ggaaactcca tttgataatt taaatgtatt
    13741 acaattttta acttctttgg gaatcaaaag agtagaatct ttaggagaaa aagaagaaga
    13801 aaaggttaaa aaaatattta gtagagatat aaaaagtaat aagaaagaga ataaatataa
    13861 aaaataactt tttaagtctt aaacttatgc ttttataaaa gggagatatg ggggatgaaa
    13921 attaaagata ataaggctgt ttttcatgta tttataagga tatttcttat agctgtttta
    13981 attttaactg gaacattatt ggaggaaaaa attaataatg ttccagttga aaatataagt
    14041 tcaaaaggtg aaaatacact ggaactgctt tctcaaagta atactttagg agaaatcata
    14101 tacaaagcat ctcaagaaga aacaaaaggt ccaggggcta cttctgaaaa agtagcatac
    14161 ataacaatag atgatggtcc atcaaaatat acaaatgcac tacttgatat tttaaaagaa
    14221 aatgatgtca aagcgacatt tttcatgctt aatcagaata tgaaaaacca caaggaagaa
    14281 gtaaggagag tcttggaaga agaaaactca ataggttttc atagtgtaag tcatgatata
    14341 cataagttat ataaaagccc agaagtaaca gttggggaat ttaatacatg caataatact
    14401 ctacaagaaa taactggtca gagttcaaaa ttaataagat taccatacgg aagtaaacca
    14461 tatatgccag aaggttcata taataaactt atggcaaatg attatttaat ttgggactgg
    14521 aatttggata cacaggattg gaagtcttct acaagtcaga tagtaagtaa tatattatat
    14581 tatggaagaa aaagagatga attagtagta ttaattcatg agaaagagca aagtttaaat
    14641 gctttaaata atattataag aatcttaaaa gagagaggat atacaatatt gccaattaca
    14701 gaaaacataa cacctaaaaa tttctggcaa gaaaacttat aataaattta aatatagtaa
    14761 aagataaagt aaattattta taaaataaaa catataatat aaaaaatacg aataagaggt
    14821 atactgtaag gataatataa tataaaatta atgagaaagc attaaaatta aaataaaata
    14881 atcttgcaat tattgacatt ataagacaga ataactgtaa aaacatattt taaaatataa
    14941 caactatata aaagagaata gacataatta agaaaattca gaaaaaataa aataaaaata
    15001 attgacaaag agaataatat ttgtatataa taatatgtaa tattaaagac tgagaagaag
    15061 aggagtaagt aaatactact aaaagagagg aaaattcact ggctgtaaga ttttctaagt
    15121 ataagattta ctgaatgtag ctttggagtt tctaaactga actataagta agtttagacg
    15181 gttagaaccg ttaaattctt tgagagtcaa agttgataaa ataacattaa ccaataattt
    15241 aatgatatgt taatgtattt taagctttgg aattaaggtg gtaacgcgag cttttcgtcc
    15301 tttttaaaga ggatgaagag ctctttttta tttctaaaga tatttaaaaa atttatttat
    15361 aaaatacagg aggcaggaca atggaaaata cgaatttatc aaaaacttat aacccaaaag
    15421 attttgaggc taggctatat aaaaaatgga tggatgaagg gtattttaaa tctaaaccaa
    15481 atccagataa aaaaccattt acaataatga tgccaccacc aaatataaca gggcaattgc
    15541 atatgggaca cgctcttgac catacacttc aagatatatt aatcagatgg aaacgtatgg
    15601 atggatatga agctttttgg cttccaggaa ctgaccatgc ttctatagca acagaagtta
    15661 aagttgttga aagaataaaa aaacaagaag gcaagacaaa gtatgaaata ggtagagaag
    15721 aatttttaaa gagagcctgg gaatggaaag atgaatttgg aggaaaaata tctaatcagc
    15781 ttaaacaact aggtgattct tgtgattggg ataaagaaag atttactatg gatgaagggt
    15841 gtaatgaagc agttatagaa ttttttgtaa gcctatatga aaaaggtcac atatacagag
    15901 gaaatagaat aataaactgg tgcccagatt gcaaaactac tttatcagat gcagaagttg
    15961 aacatgaaga acacgacgga aacttttatc atataaagta cccactaaaa gatagtgaag
    16021 actttttaga aatagctaca actagacctg agacaatgat aggagatact ggtatagcag
    16081 taaatccaga agatgataga tataaacatt taataggaaa aacagcaata cttccattag
    16141 taggaagaga acttccaata gttgcagata gttatgttga tttagagttt ggaactggtg
    16201 cagttaagat gactccagca catgacccta atgattttga agtaggatta agacataatc
    16261 ttgagcagtt aaatactatg aatgaagatg gaactatgaa tgaagtttgt ggaaaatatg
    16321 aaggtatgga tagatttgag tgtagaaaag ctatcgtagc agacttaaaa gaacaaggtt
    16381 acctaattaa gataaaagag cataatcata atgtaggaac ttgttataga tgccatacag
    16441 tagttgagcc tagattatca gagcaatggt ttgttaagat ggaagaactt gcaaaaccag
    16501 ctatagatat tcttaaaaaa ggagaattag aatttgttcc agataaattt gataaaactt
    16561 atttacaatg gctagaaaat ataagagatt ggtgtatatc aagacaatta tggtggggtc
    16621 atcaaatacc agcttattat tgtcaagagt gtggagaaat agtagttgct agaaaaatgc
    16681 cagataagtg tcctaaatgt ggaagcactc attttaaaca agatgaagat gccttagata
    16741 cttggttcag ttctgcatta tggcctttct ctactctagg atggccaaat aagactgaag
    16801 ctttagatta ttattatcca acaagtgtac ttgttacagg atacgatata atattcttct
    16861 gggtagttag aatggcattt gcaggtatgt tctgtatgaa tgaaaagcca tttgaccatg
    16921 ttttggttca tggattagta agagattctc aaggtagaaa aatgagtaaa tctttaggaa
    16981 atggtatcga cccattggag ataatcgagc aatatggagc tgatgcccta agatttacat
    17041 taacaactgg aaattcccca ggaaatgata tgagattcta tatggaaaga gtagaatttg
    17101 ctagaaactt tgcaaataag ttgtggaatg catcaagatt tgtatttatg aatattgatg
    17161 aagatataat taaaaacatg actagagaaa gtgttaaaga ggacttaact ctagctgata
    17221 aatggataat atcaagagca aataatattg taaaagaagc aactaataac atggataagt
    17281 ttgatttagg aatagcactt caaaagatat acgattttac ttggtcagaa tactgtgact
    17341 ggtatattga aatggttaaa cctagattat atggagaaga tgcaaatgct aaatctgcag
    17401 cattatatac attaacttat gttcttgaaa aaatattaaa attattacat ccatacatgc
    17461 catttataac agaggaaata tatactcatc ttcctactgt tgaaggatgt ataatagtat
    17521 ctgaatggcc aaaatataat gaagaagata acatggctga agaagaagat atgatgaact
    17581 tattgatgga aggtataaga agtataagaa atgtgagagc agaaatgaat gtaccacctt
    17641 ctaagaaagc taaattgata ataatcccaa gtgaagaaaa aatagaagct attgagcttg
    17701 gtaaagacta ttttataact ttagcatctg cttcaaatgt agagatagca aaagataaat
    17761 ctaatgttcc agaagatgca gttggagtag ttattgatgg tgttgaaata tttatacctc
    17821 ttaatgaatt agttgatttt gaaaaagaaa ttgagagatt atctaaagaa aagaaaaagt
    17881 tagaaggcga aataaagaga gttaatggaa agcttgcaaa tcaaggtttc ttagcaaaag
    17941 ctcctgaaag tttaattgaa gaagaaaaag caaaaaaaga aaaatttgaa gagatgatta
    18001 aatctgttga ggaaagatta acaaatttag aatctaaaat aaaataaata taagaattag
    18061 taaaaacata caaaaagtat atattctata ctttttgtat gtttttcttt atatatatac
    18121 aaatatgatg ttataattct ttacagatgt gttatatttt
//
LOCUS       DAMKNB010000245        16276 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.guided.084, whole genome shotgun sequence.
ACCESSION   DAMKNB010000245 DAMKNB010000000
VERSION     DAMKNB010000245.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 16276)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16276)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16276
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.guided.084"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            247..864
                     /locus_tag="PC494_003864"
     CDS             247..864
                     /locus_tag="PC494_003864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HDF3914261.1"
                     /translation="MCKKTYLLVVSMLIAGLLTACSGSPTKDSGQAQDNTKKEANASN
                     NALKDEKNNENLMEQDFKVPYTDAINIFKDKYKDADIVDLSLERDLNKFVYTVEGVDD
                     NNEYKMKIDANTKDVLEDKTEKLDSEDLNGVARKEKLDLNDIMTPQQAMEIALKEQNG
                     IVKEWSLDKDLDVTFYKIRIDKDKNEYDIKVDSKKGTVLKVEKED"
     gene            972..3503
                     /locus_tag="PC494_003865"
     CDS             972..3503
                     /locus_tag="PC494_003865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HDF3914262.1"
                     /translation="MSLKSLKIKENLYWVGSLDPDLRVFDIIMYTPYGTTYNSYVLKG
                     TEKTVLFETVKDKHFDNYIERLNDLNIDFEKIDYIVVSHTEPDHAGSVEKLLDLAKNA
                     KVVASETAIKYLKEIVNKDFEYVAVTDGDTLSIGDKTLEFFSVPMLHWPDTIYTYIKE
                     DKTLVTCDSFGSHYSNDKIVNTLDENEEKDYLDALRYYYDCIMGPFKPSMVTAIEKIK
                     DLDIDTVCPGHGPVLTENPRKIIDLYYNWSVNEQIKLEKEVTICYVSAHGYTKIMAEA
                     IKAYIEKNSNYKVNLFDVIEHKQEDILAKIAVSQGVLFGTPTILGDALKPIWDILISL
                     NPVLHGGKVASVFGSYGWSGEGIENAMERISQLRMTAVKPFAVNFKPSNEEIDKLHSY
                     TGKFLDKLNSTFGSKKKTKKFKCVICNEVFESDSAPSVCPVCGAKEDQFIEVEEDEVT
                     FRKDTDEYFVIIGNGAAGFYAADAIRKRNKTCKITMISNEDELTYYRPALSDGINEEL
                     GSDFYMEDKDWYDKNNIVVILGTNVDKLDEVNKTIIVNDGAIKFDKLVIATGSRNFIP
                     PIKGHDLENVFTLRNIKDLYSVKEALEKSKKVVVIGGGLLGLEAAWEFRLKGLEVVVV
                     EAMDSILSKQLDKEGSKILEQCVRDTGIDVRLGVAVDGIEGDGKAQKVVFKDGDSVDC
                     DMVVFSIGVRANTQMVQDTSVKIDRGIVVDKTLQTNIKDIYACGDVAQVGNISLAIWP
                     SSVEMGKIAGANASGDNLTFESEVYPVSLDAMNVKVFSIGNIQNFDKEISSKDEGQRI
                     YKKLFMKDGSLVGAILINDLSCTVKLIRLISEKGDFEDIMKADIL"
     gene            3937..4638
                     /gene="vanR"
                     /locus_tag="PC494_003866"
     CDS             3937..4638
                     /gene="vanR"
                     /locus_tag="PC494_003866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021418928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanR-ABDEGLN family response regulator
                     transcription factor"
                     /protein_id="HDF3914263.1"
                     /translation="MNENILIVDDEKEIADLIEVYLKNEGFTVYKFYTGKEALECIES
                     KDLDMAILDIMLPDIDGFHICQKIREKYYYPIIMLTAKIEDIDKIMGLTIGADDYITK
                     PFNPLEVVARVKTQLRRYMRYNNSYEQQSIIVNEYDIKGLIINKETHKCSLFGKEVAL
                     TPIEFSILWYLCEHQGKVVPSEELFEAVWGEKYLDNNNTVMAHIGRLREKIHEPSKNP
                     KFIKTVWGVGYTIEK"
     gene            4688..5761
                     /locus_tag="PC494_003867"
     CDS             4688..5761
                     /locus_tag="PC494_003867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HDF3914264.1"
                     /translation="MRTALMAFIAIIFIWILYSFILYGKFSIWIVSFFENAFRMEYKA
                     ALNLYQQIFRNSMELFMILAMVIVFFIIFRVYLNWFTKYFSEINQGIDSLIKEDVGEV
                     ALSPELLAIEKKINSIKHILEQRKFETQMAEQRKNELIVYLAHDLKTPLTSVIGYLTL
                     LRDESQISEELRKKYLSISLDKAERLEDLINEFFEITRFNLSNISLEYSTVSLTRMLE
                     QLTYEFKPTLMSKNLKYTLNVTPNMMIRCDVNKMQRVFDNLLRNAVYYSFEDTTIEIT
                     AVQEDDYIKLKFMNHSNTIPEEKLERIFEQFYRLDTSRNSNSGRAGLGLAIAKEIVEL
                     HNGTITAHSENNIITFKVIIPIV"
     gene            6031..7131
                     /locus_tag="PC494_003868"
     CDS             6031..7131
                     /locus_tag="PC494_003868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021418924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HDF3914265.1"
                     /translation="MNNKKIAVIFGGNSTEYDVSLQSAFAVLENLNTEKYDIIPIGIT
                     REGNWYHYIGDYNNIQNNTWFERDTDIIPVIVSQNRVKNGIIEFLISDAVSQNHIPNS
                     AIESCENDIKYTKLDFVFPILHGKNGEDGTVQGLFELAGIQVIGCGTLSSALCMDKDK
                     SHKLVHSEGIKVPKSILLKYSDKFNVAELSKDLTYPLFIKPVRAGSSFGISKIYKKEE
                     LQVAVDLAFEHDNEVIIEENIDGFEVGCAVLGNDDLLVGRVDEIELSKGFFDYTEKYT
                     LKSSKIHMPARIDLDCEKRIQETAKIIYRTLGCSGFARVDMFLTPSGEIIFNEVNTIP
                     GFTSHSRYPNMMKGIGLSFEEILDKIIEVYIK"
     gene            7128..7934
                     /locus_tag="PC494_003869"
     CDS             7128..7934
                     /locus_tag="PC494_003869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HDF3914266.1"
                     /translation="MMNNILLDKNKEDKMTNTILLTKDKVYDGNLILVNAFLPVKTSE
                     DIDLIPVDTRFPSILMKREATNILQNILKSICGINEIVPVSGYRTAEEQQDIYSSSLR
                     DNGKDFTKKFVALPNHSEHQTGLAIDLGLKKEVIDFICPEFPYNGICNEFRKAALHYG
                     FIERYQCKKEEITGISQEPWHFRYVGYPHSEIINKMNLALEEYIEYIKRFSYTNCLKI
                     EDKEKIIEIFYVPIHTKEEVRISIPEQCVYQISGNNKDGFIVTFWRNRKD"
     gene            7952..10090
                     /gene="vanT"
                     /locus_tag="PC494_003870"
     CDS             7952..10090
                     /gene="vanT"
                     /locus_tag="PC494_003870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021418922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine racemase VanT catalytic subunit"
                     /protein_id="HDF3914267.1"
                     /translation="MIRNKSYAGLDYFRIIAALLIIAIHTSPLLSYSKMADFVLTSII
                     ARIAVPFFFMLSGFFLISTYNYNCNKLKSFLKNVLFIYGIAIVIYIPLNIYTGYFSMN
                     NLVPNIIKDIVFDGTLYHLWYLPASIIGASIAYFLVKKLGLKYSLVITIVIYVIGMFG
                     DSYYGFLEKIPLLKNLYGYIFEVSDYTRNGIFFAPVFFILGGIISNKSNYMSTKNSLI
                     GFLISFLLMLCEGMFLHKLGVQRHDSMYIMLLPCMYFLFTALTFLKGSRARLLRTSSL
                     IIYIIHPMMIVVIRMFSKIFGIQTVLVDNSLIHYIVVSIASFIASIIIILILKPIKKD
                     LKGEHKVNTNRAWIEIDLNNLEHNVKMIQKAMPEDCELMAVVKANAYGHSAFEVATCA
                     NQIGVKAFAVATIDEGIDLRRYGILGEILILGYTNPIRAKELHKYNLTQSVIDLNHAI
                     SLNKQKYNIKSHIKIDTGMHRLGFDVNDVRSILKAFKLKYLDICGIFTHLCVSDSLKD
                     EDVDFTNKQIECFYKLIDFLLKKGIKIPKVHIQSSYGFFNYPNLKCNYVRIGIALYGI
                     LSSPNDTTKLQLDLRPVLSLKSQVILIRKIQKDDSFGYGRVFIASRDSVIAILSIGYA
                     DGIPRNLSCGKSYVIINGCRAAIVGRICMDQLAVDITDIPNVEVGNTAIIIGRDNLSE
                     LSASEVANNSCSISNELLSRVGRRLNVIKK"
     gene            10404..11024
                     /locus_tag="PC494_003871"
     CDS             10404..11024
                     /locus_tag="PC494_003871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HDF3914268.1"
                     /translation="MQYIQELLDLTQNYWVLATIIGLLSAFIESFIPALPLVAIVTAN
                     AAIQGLFIGCLLSWIGSGLGTTSLFLLISRFNDSKLFNKLRNSKTEKAISWMDKQGFK
                     LLFIAYACPFMPGCLVTIASAFGKKDLKDFVPAMLAGKFVMFIVISYVASDIEGFITS
                     PLKIASFILLVFLSWKIGNRVNKNLENHNYDFHHKKHHNDKDDKMI"
     gene            complement(11190..11726)
                     /locus_tag="PC494_003872"
     CDS             complement(11190..11726)
                     /locus_tag="PC494_003872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HDF3914269.1"
                     /translation="MIKETHERGGYIFALLILPFINNLYLVKYDIAYKIVLIIIYIYF
                     AYLGSLFPDIDMRGSYISKKFMLIYKLFGSRFRHRGFTHSLIALLLIYSFFKSLTIFT
                     NNNIVFSCLSSGFIIGYLSHLCLDLITKEGIELFYPITINISLLPIKTNSKTEKFISK
                     LLNFIVIFLIGYQFYILL"
     gene            complement(11839..12513)
                     /locus_tag="PC494_003873"
     CDS             complement(11839..12513)
                     /locus_tag="PC494_003873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000094049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HDF3914270.1"
                     /translation="MSLFIISQCITSFAFTPENNKFKVKPLPYAYDALEPYIDKETMK
                     LHHDKHYQAYVDKLNAALEKYPELYNYSLCELLQNLDSLPKDIATTVRNNAGGAYNHK
                     FFFDIMTPEKTIPSESLKEAIDRDFGSFEKFKQEFQKSALDVFGSGWAWLVATKDGKL
                     SIMTTPNQDSPVSKNLTPIIGLDVWEHAYYLKYQNRRKEYIDNWFNVVNWNGALENYK
                     NLKSQD"
     gene            12716..14590
                     /gene="asnB"
                     /locus_tag="PC494_003874"
     CDS             12716..14590
                     /gene="asnB"
                     /locus_tag="PC494_003874"
                     /EC_number="6.3.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase (glutamine-hydrolyzing)"
                     /protein_id="HDF3914271.1"
                     /translation="MDGNISIYYKGDISKKEDIKFKIKESVNNTRLSSRIEYKDEEKT
                     FDFERFNVIDAIYGNKPFEKDGKVIVFNGNIYNYHEIKEELIKKGHNFTTNDDIEVLL
                     ASYIEFGKNCVHKIKGMFNFIIYDRENESIFGARDLFGIKPLYYINKENAIIFSSEYK
                     FLLEYMKNLNINERSLQSYFSFQYVLPEDTMIQGIRLIPAGHYFRVENGILSLKRYNK
                     LEFRSSTKFFYTKNHLGNRDVNEDDIRNIVVDSIVTHMEEEKEIGTFLSGGIDSSIIT
                     TVASQINPNIKSFSAGFSVKGYSELEVAKKTADKLGIENIQINITQDEYIKSLPNVIY
                     SLDDPIADPSEVGLYFLIKEAGKHVKVALSGEGADELFGGYNIYKEYSTMKSVVNSPT
                     YIKSILGRVSELMPNIKGRNYLYRATTPLEKRYIGNAKVFENSEVKRFFFKYKEKNIY
                     EYLLSNLYRDAQKNNYDYISKMQHIDVNTWLQGDILQKISKLSTAEQVELRVPFLYKD
                     VFDVAKNLRMEQKINKNNTKVLLREAFREIVPEHVVQRKKLGFPTPIRVWLKDSLGDI
                     VKETIYNSNVDEFIDKKYAIKLLDTHLKGHRDNSRKIWTIFTFCLWHQLFIEHKNVEY
                     "
     gene            complement(14682..16118)
                     /locus_tag="PC494_003875"
     CDS             complement(14682..16118)
                     /locus_tag="PC494_003875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HDF3914272.1"
                     /translation="MICTIKPLKISIKKSTEPLIEFISDTTYKNKSSSYIKEVYFTRY
                     IGVDDSIDKYIEKIKNIDTYFFNNPTIPYIRLNNLKINFDKEQTDKMLKIFNIYNSSK
                     FNSWDLYNIDFPCKIENDTLNWTKKIAFKNTLDLFSTSMPNCTSSIIKNFAVKLLCWI
                     DYFLPKLFYNKVKTTISPKIVYFGNIKRQELFFLYFLSQLGCDILYINPNKDILDLYP
                     ECSKFSTLFELSRKTPNILEIPFERHITNINYSENTNKTSPTTNKPNSKNTLNNTNLT
                     SKKIVQDEEVELSYEDLAKLSASVVMIVVCNNENKPFKSGSGVVINNEGYILTNLHVV
                     NDGYSFLVRFENDDKVYTSYQIIKYHSDYDLAVIKVDRKCKPIPVKVSKKPVRGQKIV
                     AIGSPLGLFNTVSDGIISAFRDFETVQMIQFTAPISSGSSGGALLDMFGNLLGLISAG
                     YDDGQNLNLAVESSLVKIFANNFIEIVN"
BASE COUNT         6211 a         1774 c         2716 g         5575 t
ORIGIN      
        1 tcaaaatgaa ctttttagtt catgaggcac tctttttgta cgaaataaaa tatattttta
       61 ttatttcaac aatgaaaaag aggcttgttt ccattttgag acagtataat ttttatgtaa
      121 ctttaatttt agtaaatata aagttttaaa attgataaaa taggaggaat ttttaatata
      181 aaagggtaaa taaagggttt agagggcata atatagaata aattaatata tttaaggagg
      241 gtttttatgt gtaaaaaaac gtatttatta gtggtaagta tgcttatagc gggtttatta
      301 actgcatgta gtgggagtcc aactaaggat tcaggacaag cacaagataa tacaaaaaag
      361 gaggcaaatg catcaaataa cgctttaaaa gatgaaaaaa ataatgaaaa tttaatggaa
      421 caagatttta aagtgccata cacagatgca ataaacatat ttaaagataa atataaggat
      481 gctgatatag tagatttaag tcttgagaga gatttaaata aatttgttta tactgtggaa
      541 ggtgtagatg ataataatga atataagatg aaaattgatg ctaatacaaa agatgtatta
      601 gaagataaaa cagaaaagtt ggattcagaa gatttaaatg gagttgctag aaaagaaaaa
      661 ttagatttaa atgacataat gacacctcaa caagctatgg aaattgcatt aaaagaacaa
      721 aatggaatag ttaaagaatg gagtttagac aaagatttag atgttacttt ttataaaata
      781 agaatagata aagataaaaa tgaatatgac ataaaagtag attctaaaaa gggaactgta
      841 ttgaaggtag aaaaagaaga ttagaagatt taaactatct ttaaaataat ttcttttttg
      901 aataaatttt gtttaaaata taacaagcag ggtataaaga gactaaataa ctattttagg
      961 aggagtacgg tatgtcattg aaatcactaa aaataaaaga aaatttatat tgggtaggtt
     1021 cgcttgaccc tgatttaaga gtatttgaca taattatgta tacaccttat ggaactactt
     1081 ataattcata tgtattaaaa ggaacagaaa aaacagtttt atttgagaca gttaaagata
     1141 agcattttga caattatatt gaaagattaa atgatttaaa tatagatttt gaaaaaatag
     1201 actatattgt tgtaagtcat actgaaccag accatgcagg aagcgttgaa aagcttttgg
     1261 atttagctaa aaatgcaaaa gtagtagctt cagaaacagc aattaaatat cttaaggaaa
     1321 tcgtaaacaa agactttgaa tatgttgcag ttacagatgg agatacatta tcaattgggg
     1381 acaaaacttt agaatttttc tctgtaccta tgcttcattg gccagatacc atatacacat
     1441 atataaaaga ggataaaact cttgtaacat gtgattcatt tggtagtcac tatagtaatg
     1501 ataagatagt aaatacactt gatgaaaatg aagaaaagga ttacttggat gctttaagat
     1561 actattatga ttgtataatg ggtccattta aaccatctat ggtaactgct atagaaaaga
     1621 taaaagattt agatatagat actgtatgtc caggtcatgg tccagtatta actgaaaatc
     1681 ctagaaaaat tatagacctt tattacaact ggagtgtaaa tgaacaaata aagttagaaa
     1741 aagaagttac aatttgttat gtttctgcac atggatatac aaagattatg gcagaagcta
     1801 taaaagcata tattgaaaaa aatagcaact ataaagtaaa tttatttgat gtaatagagc
     1861 ataagcaaga agatattttg gcaaaaatag cagtatcaca aggtgtatta tttggaacac
     1921 caacaatatt aggagatgcg ttaaagccta tatgggatat attaatatcg ttaaacccag
     1981 ttcttcatgg tggaaaagtt gcttcagtat ttggttcata tggatggagt ggagaaggta
     2041 tagaaaatgc tatggagaga ataagtcagc ttagaatgac agcagtaaaa ccttttgctg
     2101 ttaactttaa accatcaaat gaagagattg ataaattaca ttcttataca ggtaaattcc
     2161 tagataagtt aaattctact tttggaagta aaaagaaaac taagaaattt aaatgtgtaa
     2221 tttgtaatga agtttttgaa agtgatagtg ctcctagtgt atgccctgta tgtggagcta
     2281 aggaagacca atttatagaa gttgaagaag atgaagttac ttttagaaaa gatactgatg
     2341 aatatttcgt aataatagga aatggagcag ctggttttta tgcagcagat gctataagaa
     2401 aaagaaataa aacttgtaag ataactatga tttctaatga agatgagttg acttactata
     2461 gacctgcact ttctgatggt ataaatgaag aacttggttc agatttctac atggaagata
     2521 aagattggta tgataaaaat aatatagtag taatattagg aacgaatgta gataaattag
     2581 atgaagtgaa taaaactatt atagtgaatg atggagctat taaatttgat aagcttgtaa
     2641 tagctacagg aagtagaaac tttataccac caattaaggg tcatgattta gaaaatgtgt
     2701 ttactcttag aaatataaaa gatttatata gtgtaaaaga agcactagaa aaatctaaga
     2761 aagttgtagt gattggtggc ggtttattgg gacttgaagc tgcatgggaa tttagactaa
     2821 aaggattaga agtagtagta gttgaagcca tggatagcat actatcaaaa caacttgata
     2881 aagaaggtag taaaatatta gaacaatgtg taagagatac aggaatagat gtaagattgg
     2941 gtgtagcagt tgatggtatt gaaggtgatg gaaaagctca aaaagttgta tttaaagatg
     3001 gagatagtgt tgactgtgat atggtagtat tttcaattgg tgtaagagca aacactcaaa
     3061 tggttcagga tacatctgta aaaattgata gaggtattgt tgtagataag acattacaga
     3121 caaatattaa agatatatat gcttgtggag atgttgcaca agtgggaaat attagtttag
     3181 caatatggcc atcttcagta gaaatgggaa aaatagcagg ggcaaatgca agtggagata
     3241 atttgacatt tgaaagtgaa gtatatccag tttcattaga tgcaatgaat gtaaaagtat
     3301 ttagtattgg taatatacaa aattttgata aagaaatttc atcaaaagat gaaggtcaaa
     3361 gaatatataa aaaattattt atgaaagatg gttcattagt tggagctata cttataaatg
     3421 atttaagctg tactgttaaa ttgataagat taatatctga aaaaggtgat tttgaggata
     3481 ttatgaaggc tgatatacta taatttaaat acattaaaat aaaaaggagt tgtctcaaaa
     3541 ttgatttttt tctaatcaaa ttttaaattc aactcctttt ttgaattttt atataaaata
     3601 acatggaaat tttagtaatg tctgtggtta catacatagg tttaattgtt ttttatatgg
     3661 attgtctctg gtataataaa ttgaattgtg tttgactgat agatattttt attgaaagtt
     3721 aatacctgtt atgcgataat aaggacgtgt taggggagtt tttataataa caattaatct
     3781 cagtttttgt gttccaatag tagcatcaac acattctgat gtagtagttc ttttcttata
     3841 aaaattagtt acaaatatgc ttgtaattat ttgatatgta aatttaccaa tattataaat
     3901 gatgacctcg ataataagga gagtgaaaaa taatctatga acgaaaatat tttgattgtg
     3961 gatgatgaaa aagaaatagc agatttaatt gaagtatatt taaaaaatga aggttttaca
     4021 gtatacaagt tttatacagg taaggaagct ctagaatgta ttgaatctaa agatttggat
     4081 atggctattt tagatattat gcttcctgat attgatggat ttcatatttg ccagaaaatt
     4141 cgagaaaaat actattatcc tatcattatg ttaacagcta aaattgaaga tatagacaag
     4201 ataatgggtt taaccatagg tgctgatgat tatataacaa agccatttaa ccctttggaa
     4261 gttgttgcaa gagtaaagac acaattaaga agatatatgc gatataataa ttcttatgaa
     4321 caacagtcga taattgttaa tgagtatgat attaaaggat tgattatcaa taaagaaaca
     4381 cataaatgta gtttatttgg gaaagaagta gcattaacac cgattgaatt ttctattctt
     4441 tggtatttat gtgaacatca aggaaaagtg gttccttctg aagaattgtt tgaagctgta
     4501 tggggagaaa aatatcttga taataataac acagttatgg ctcatatagg gcgattacgt
     4561 gaaaaaattc atgaaccttc taaaaacccg aaatttataa aaactgtatg gggagtaggt
     4621 tatacaattg aaaagtaaaa atattaaagt caatcctgac tttactcaag tgagaaataa
     4681 aatttttatg agaacagctt taatggcatt tatagccatt attttcatat ggattttata
     4741 ttcttttata ttgtatggta agttttctat ctggatagta tcattctttg aaaatgcttt
     4801 tcgtatggaa tataaagctg cattgaattt atatcagcag attttccgta atagcatgga
     4861 gctcttcatg atactagcta tggtgattgt gttttttata atattccgtg tttatttaaa
     4921 ttggtttaca aaatatttta gtgaaataaa tcaaggtatt gactctctta tcaaagaaga
     4981 tgttggagaa gtggctttat ctccagagtt attggcaata gaaaagaaaa taaactcaat
     5041 taaacatata cttgaacaac gtaaatttga gacacaaatg gcagaacaac gtaagaatga
     5101 acttattgtt tatcttgcac atgatttaaa aacaccactt acatcagtta tagggtatct
     5161 gacactactt cgagatgaaa gtcagatttc tgaagaactg cgaaaaaaat atttatctat
     5221 ttcgttggat aaggcagagc gtcttgaaga tttaattaat gaattctttg aaattacaag
     5281 gtttaattta tcaaatatat cacttgaata cagtacagta agcttaactc gtatgcttga
     5341 acaactaaca tatgagttta aacctacttt gatgagtaag aatttaaaat atacactgaa
     5401 tgttacacca aatatgatga taaggtgtga tgttaataaa atgcaacgtg tatttgataa
     5461 cttattacga aatgctgttt attatagttt tgaagatact actattgaaa taacagctgt
     5521 acaggaggat gattatataa agcttaaatt tatgaatcat agcaatacga ttccagagga
     5581 aaaacttgag cgtatttttg aacaatttta caggttggat acatctcgta attcaaacag
     5641 tggtagagct gggttgggac ttgctatagc taaagaaata gtggagcttc ataacgggac
     5701 aataacagct catagcgaga acaatataat tacctttaag gttattattc cgattgtatg
     5761 aaatttgtaa gaatttaagt ataaaaaaat aggaaattct ttaggataaa taaataaaga
     5821 gcactcttgt tattgatata attactgtat caaaacaaga gtgcttttat tttgatacag
     5881 taattatatc aatagaaaaa tgtgaaaata tattatgtgg aacagatgca attgtaagtg
     5941 aaggttgatt ggatttgaaa tagaaaaagt attttaacat gtttctgtag attgtataaa
     6001 aataaataaa tcaacaaagg agaatcaaag atgaataata aaaaaattgc agttatattt
     6061 ggtggaaact caacagaata tgatgtatca ttacaatcag cttttgcagt acttgagaat
     6121 ttgaatacgg aaaaatatga tattatacca attggaatta caagggaggg taattggtat
     6181 cattatattg gagattataa taatatccag aataacactt ggtttgaaag ggatactgat
     6241 ataattccag ttattgtttc gcagaaccgt gtcaaaaatg gtattattga atttttaatt
     6301 tctgatgctg tttctcagaa tcatattcca aatagtgcta ttgaatcatg tgaaaatgat
     6361 attaaataca ctaaacttga ttttgtattt cctatattgc atggaaaaaa tggagaagat
     6421 ggaacagtgc aggggttatt tgaattggca ggtatacagg ttattggatg tggtactctt
     6481 tcttcagcat tatgtatgga caaagacaaa tcacataaac ttgttcattc agaaggtatt
     6541 aaagtaccaa aatcaatatt actaaaatac tcagataaat ttaatgtggc tgaactgtca
     6601 aaagacttaa cttatccatt atttataaaa cctgtgcgtg caggttcatc atttggtatt
     6661 agtaaaattt ataaaaaaga agagttacaa gtagcagtag acttggcttt tgaacatgat
     6721 aatgaagtaa taattgagga aaatattgat ggttttgagg tagggtgtgc agttttagga
     6781 aacgatgact tacttgttgg aagagtagat gaaatagaat tgtcaaaagg attttttgat
     6841 tatacagaaa aatatacatt gaaaagttca aaaattcata tgccagctag aattgatttg
     6901 gattgtgaga aaagaataca agagacagca aaaattattt atagaactct tggatgttct
     6961 ggatttgcta gagtggatat gtttttaact ccatctggtg aaattatttt taatgaagtc
     7021 aatacaattc ctggctttac ttctcatagt cgttatccaa atatgatgaa aggtattgga
     7081 ctgtcttttg aagaaatatt ggacaagata attgaggtgt acataaaatg atgaataata
     7141 ttttattaga taaaaataaa gaagataaaa tgacaaatac tatcttattg actaaagata
     7201 aagtttatga tgggaatcta attctagtaa atgctttttt accagttaaa acatctgaag
     7261 atatagattt aattcctgta gatacaaggt ttccaagtat tcttatgaaa cgtgaagcta
     7321 caaacatttt acaaaatatt ttaaaaagta tatgtggaat aaatgaaata gtacctgtaa
     7381 gtggatatcg tactgcagag gaacaacaag atatatattc aagttctctg cgtgacaatg
     7441 gaaaagactt tactaaaaag tttgtagcac ttccaaatca cagtgaacat cagacagggc
     7501 ttgctattga tttagggtta aagaaagaag ttatagattt tatctgccct gaatttcctt
     7561 ataatggtat ttgtaatgag tttcgtaagg cagcactaca ttatggtttt atagagcgtt
     7621 atcagtgtaa aaaagaagaa ataacaggaa tatctcaaga accatggcat tttcgttatg
     7681 tgggatatcc gcattctgag attatcaata aaatgaatct cgctcttgaa gaatatatag
     7741 aatatattaa gagattttcg tatacaaatt gtttaaaaat agaagataaa gaaaaaatta
     7801 tagaaatctt ttatgtacct attcatacta aagaagaagt gagaatctct atacctgaac
     7861 aatgtgtata tcaaatatcg ggtaacaata aggatggttt tattgtgaca ttttggagaa
     7921 atagaaagga ctaagaaatg gaggaacaag aatgattagg aataaatctt atgcagggct
     7981 tgattatttt aggattatag ctgcattact tataattgca attcatacat ctccattatt
     8041 atcatatagt aaaatggctg actttgtgtt aactagtata attgctcgta ttgctgtgcc
     8101 attctttttt atgctatcag gcttttttct aatttcaaca tataattata attgtaataa
     8161 actgaaatct tttctaaaaa atgtattatt tatttacggg atagctattg taatttatat
     8221 tcccttaaat atttacactg gatatttttc catgaataat ttagtgccca atattattaa
     8281 ggacattgta tttgatggga ctttatatca tttatggtat cttcctgcat caattattgg
     8341 tgcaagtatt gcatactttc ttgtaaaaaa actaggttta aagtactcac tagtaatcac
     8401 tattgttatt tatgtaattg gtatgtttgg tgatagttat tatggttttt tagaaaaaat
     8461 accactatta aagaatttat atgggtatat ttttgaagta tcagattata cacgaaatgg
     8521 tatatttttt gcacctgtat ttttcatact tggtggaata atatctaata aatctaatta
     8581 tatgtcaact aaaaatagct tgattggatt tcttatatca ttcttactta tgttatgtga
     8641 gggaatgttt ttacataaac taggggtaca gcgtcatgat agcatgtata ttatgttatt
     8701 gccatgtatg tatttcttat ttacagcctt aacatttttg aaaggttctc gagctaggtt
     8761 attgcgaaca tcatcattaa ttatttatat tatacatcct atgatgattg ttgttattcg
     8821 tatgttttct aaaatattcg gaatacaaac tgtcttggtt gacaatagcc ttattcatta
     8881 tatagtggta agtatagcat cttttatagc ttctataatt attatattga ttcttaaacc
     8941 tataaaaaaa gacttgaaag gagaacataa ggtaaatacc aatagagctt ggattgaaat
     9001 tgatttaaat aatttggaac ataatgtaaa gatgatacaa aaagctatgc cagaagattg
     9061 tgaattgatg gcagttgtaa aagctaatgc ctatggtcat agtgcttttg aagtagcgac
     9121 ttgtgcaaac caaataggtg taaaagcatt tgcagtagca acaatagatg aggggattga
     9181 tttacgtcga tatggaatac taggagaaat attgattctt ggatatacta acccaataag
     9241 ggcaaaggaa cttcataaat acaatcttac acagagtgtt attgacctta atcatgctat
     9301 ctctttaaac aaacagaaat acaacataaa atcacacatt aaaattgata caggtatgca
     9361 cagactgggt tttgatgtta atgatgtgag gtcaatttta aaggcattta aattaaaata
     9421 cttagatata tgtggcatat ttacacactt gtgtgtttca gatagtctga aagatgaaga
     9481 tgtagacttt acaaataaac aaattgaatg tttttataag ttaattgatt ttctgttaaa
     9541 aaaaggtata aaaattccta aagtacatat tcaaagtagt tatggttttt ttaattatcc
     9601 caatcttaag tgtaattatg taagaattgg aattgcatta tacgggatat taagttctcc
     9661 aaatgatacg actaaattgc aacttgattt acgacctgtt ttatccttaa aatcacaagt
     9721 aattcttatt agaaaaatac aaaaagatga tagttttgga tatggaagag tctttattgc
     9781 aagcagagat agcgtaattg ctatattatc tattggctat gccgatggta tacctagaaa
     9841 tttatcctgt ggaaaaagtt acgtaataat aaatggttgt agagcagcaa tagtgggtcg
     9901 aatttgcatg gaccaacttg ctgttgatat tacagatata cctaatgtag aagttggtaa
     9961 tacggcaata ataataggaa gagataattt atctgaatta tctgcttctg aagttgcaaa
    10021 taactcatgt agtatatcaa atgaattatt gagcagagta ggaaggaggt taaatgttat
    10081 aaagaagtaa ctcaattaaa tagtaatatt tgttgtactg tgtaatttat tttactctga
    10141 ctagacattt ttagtaatat tatgtctaat atatattttt tataacttac atgacaattt
    10201 aagctataaa aaggtgatgt ttcagatttt tattttgaaa catcaccttt tttgttataa
    10261 tatataataa aataattata ccttaactgt aaacttatat agattattta ctttttaata
    10321 ttagattcat tttttgagat tggtatataa taaacatata gagtatataa taatagttaa
    10381 agttaaaaaa ggggaaaagc aatatgcagt atatacaaga actacttgat ttgactcaaa
    10441 attattgggt gttagccaca ataatcggct tattaagtgc atttatagaa agctttatac
    10501 cagccttacc acttgttgct atagttacag caaatgctgc aatacaagga ttatttattg
    10561 gatgtttgtt atcatggatt ggctcaggac ttgggacaac ttcattattc ttattaataa
    10621 gcagatttaa tgatagtaag ctttttaata agttgagaaa tagtaaaact gaaaaagcaa
    10681 taagttggat ggataaacag ggatttaagt tattatttat agcgtatgcc tgtccattta
    10741 tgcctggttg tttagttact atcgcatcag cttttggtaa aaaagattta aaagattttg
    10801 tgccagcaat gttggcagga aaatttgtaa tgtttatagt tataagttac gtggcaagtg
    10861 atatagaagg ttttataaca agtcctttaa agatagcatc atttatatta ttggtgtttt
    10921 tgtcatggaa gattggaaat agagtaaata aaaatcttga aaatcataat tatgatttcc
    10981 atcataaaaa acatcacaat gataaagatg ataaaatgat ttagcttgta cgaaataaaa
    11041 cgtatcttaa aatgatttag tactaaatta ttttaagata cgttttattt tttgtattaa
    11101 ggtacaaaat ttttagttct tttgtaaact aaaatatata aaacttattt atacttagtt
    11161 caaaatattg ttatttattt tttctacaac tataataaaa tataaaattg atatccaatc
    11221 aaaaaaataa ctatgaaatt taatagctta gatatgaatt tttctgtttt tgagttagtt
    11281 tttataggta gtaaagaaat gtttatggta atgggataaa acaattcaat accttcttta
    11341 gtaataaggt caagacacaa gtgagataga tatcctatta taaacccact ggacaaacat
    11401 gagaaaacta tattattgtt agtgaagatt gtcagagatt taaaaaaact ataaataagt
    11461 aataaggcaa ttagactgtg agtaaaccct ctatgtctaa acctacttcc aaataatttg
    11521 tatattaaca taaatttttt acttatgtaa gaacctctca tatctatatc tggaaataaa
    11581 gaacctaaat atgcaaaata aatataaatt ataattaata ctattttata tgcaatatcg
    11641 tatttaacta ggtacagatt gtttataaag gggagtatca aaagtgcgaa tatataacct
    11701 cccctttcat gtgtttcttt tatcatataa aaatcctcct gaatcgtcac tataaacatt
    11761 atattggtaa atttagacta tcttttatta tattatatag caaacataag tttttttcaa
    11821 aaggatttta atatttaatt aatcttgaga ttttaaattt ttgtaatttt ctaaagcacc
    11881 attccaattt actacattaa accagttgtc aatgtattct tttcttctat tttgatattt
    11941 taaatagtaa gcatgctccc aaacatcaag tcctattata ggagttaggt ttttacttac
    12001 agggctatcc tgatttggag tagtcataat agataatttc ccatctttag tagctacaag
    12061 ccaagcccaa ccagaaccaa agacatctaa agcagatttt tggaactctt gcttaaattt
    12121 ttcaaaagaa ccaaagtctc tatcaatagc ttcttttaaa gattcagaag gtatggtttt
    12181 ttctggcgtc attatatcaa aaaagaattt atgattataa gctccacctg cattatttct
    12241 tacagttgta gcaatatctt taggtaaaga atctaaattt tgcaataatt cacataaaga
    12301 ataattataa agctcaggat atttttcaag agcagcattt aatttatcaa cataagcttg
    12361 ataatgctta tcatgatgca gtttcattgt ttctttatct atataaggtt caagtgcatc
    12421 atatgcataa ggtaatggtt taaccttaaa tttgttattt tcaggtgtaa aagcaaatga
    12481 agttatgcac tgtgagatta taaataaaga cataataact ggtattaata tttttttctt
    12541 cataaaaatc acctcctaat atagtatttc tagaaataaa aaaaatatga aatattaaca
    12601 gataatttat aagaatttaa tagcaatttc attttaaatt gaataagttt taaagccaaa
    12661 gacaaaacta tgaaatatag aataagacta aaggacagaa aggaattttg attatatgga
    12721 cggcaatatt tcaatttatt ataaaggtga tatatctaaa aaagaagata ttaaatttaa
    12781 aataaaagaa tctgtaaata atacaagact ttctagtaga atagagtata aggatgagga
    12841 aaaaactttt gattttgaaa gatttaatgt aattgatgct atttatggaa ataaaccatt
    12901 tgaaaaagat ggaaaagtta ttgtttttaa tggaaatata tataactatc atgaaataaa
    12961 agaagaatta attaaaaaag gacacaattt tactacaaat gatgatattg aagtcttatt
    13021 agcatcttat atagaatttg gtaagaattg tgtacataag attaaaggaa tgttcaactt
    13081 tataatctat gatagagaaa atgaaagtat atttggagca agagatttat ttgggataaa
    13141 accactttat tatataaata aggaaaatgc aataattttt tcctcagagt ataagttttt
    13201 acttgaatat atgaaaaatt taaatataaa tgaaagaagc ttacaaagtt atttttcatt
    13261 tcaatatgta cttcctgaag atactatgat acaaggaata aggctgatac cagcaggtca
    13321 ctattttagg gtagaaaatg gtatactatc tttaaagaga tataataaac ttgagtttag
    13381 aagtagtaca aaattttttt atactaaaaa tcacttaggc aatagagatg tgaatgagga
    13441 tgatataaga aatatagtag tagattcaat agtaactcat atggaagagg agaaagaaat
    13501 tggaacattt ttgtctggtg gaatagattc atctattata actactgtgg cttcacaaat
    13561 taatccaaat ataaaatctt tttctgcagg ctttagtgtc aaaggatata gtgaattaga
    13621 agtagcaaag aaaacagctg ataagttagg tatagaaaat atccagatta atataacaca
    13681 agatgaatat ataaaatcat taccgaatgt aatttattct ttggatgacc ctatagcaga
    13741 cccttcagaa gtaggtcttt atttcttaat taaagaggca ggtaaacatg ttaaagtagc
    13801 attgtctgga gaaggagcag atgaattatt tggaggatat aatatatata aagagtatag
    13861 tactatgaaa tcagttgtca attcacctac ttatattaaa agtatattag gaagagtttc
    13921 agaacttatg ccaaacataa aaggaagaaa ttatctttat agagctacaa caccattaga
    13981 aaaaagatat ataggaaatg caaaagtttt tgaaaacagc gaagtaaaaa gattcttttt
    14041 taagtataag gaaaagaata tatatgaata cctgttgtct aatttgtata gagatgcaca
    14101 aaaaaataat tacgattata taagtaaaat gcaacatata gatgtgaata catggcttca
    14161 aggcgatata cttcaaaaaa ttagcaaact ttctacagct gagcaggttg aacttagagt
    14221 accattttta tataaagatg tatttgatgt cgcaaaaaat ttaagaatgg agcaaaaaat
    14281 aaataagaat aatacaaaag ttttacttag agaggcgttt agagaaatag tcccagaaca
    14341 tgttgttcaa aggaaaaaat taggatttcc aactccaata agagtttggt taaaagattc
    14401 tctaggggat attgtaaagg aaactattta taattcaaat gtagatgaat ttatagataa
    14461 aaaatatgca ataaaacttt tagatacgca tcttaaaggt catagagata attcgagaaa
    14521 aatatggact atatttacat tttgtctatg gcatcaatta tttattgagc ataaaaatgt
    14581 cgagtattaa tacttttttc aatattaatc agagggcaaa agcatgcaat gttttcaccc
    14641 tcttgattat tatggaatag gataagtaga attttgattg attagtttac tatctcaata
    14701 aaattattgg caaatatttt gacaagacta ctttcaacag ctaaatttaa gttttgtcca
    14761 tcatcatatc cagcggaaat caatcctagt aagtttccaa acatatctaa aagagctcct
    14821 cctgaactac cactagagat tggagctgta aattgtatca tttgaaccgt ttcaaaatca
    14881 cgaaaagctg aaataattcc atctgaaact gtattaaaaa gacctagagg gcttccaatt
    14941 gcaactattt tttgacctct cacaggtttt ttactgactt taacaggtat tggcttgcat
    15001 tttctatcaa cctttatcac agctaaatca taatctgaat ggtattttat aatttggtaa
    15061 gatgtataaa ctttatcatc attttcaaat ctaactaaaa atgaataccc atcattgact
    15121 acatgaagat tcgtaagtat ataaccttca ttatttatta ctactccaga accgctctta
    15181 aacggtttat tttcgttatt gcacacaaca atcataacaa cagaagctga taactttgca
    15241 aggtcttcat aagaaagttc tacttcctca tcttgtacaa tttttttaga tgttagattt
    15301 gtgttattaa gtgtattttt agagttaggt ttattcgtag taggagaagt cttattggta
    15361 ttttcactgt aatttatatt tgtaatatgc ctttcaaaag gtatttctaa tatatttgga
    15421 gtcttcctag aaagttcaaa tagagtagaa aattttgaac attcaggata taaatcaaga
    15481 atatctttat ttggatttat atataaaata tcacacccaa gttgtgataa aaaatataag
    15541 aaaaaaagtt cttgcctttt aatatttcca aagtatacta tctttggtga aatagtagtc
    15601 ttcaccttgt tataaaataa tttaggtaga aaatagtcta tccaacacaa aagtttaact
    15661 gcaaagtttt tgatgataga ggatgtacaa tttggcatac ttgtggaaaa taaatctaaa
    15721 gtatttttaa atgcaatctt tttagtccaa tttaaggtgt cattttctat tttacatgga
    15781 aagtcgatat tatataaatc ccaactgtta aacttagaac tattataaat attaaaaatt
    15841 ttaagcatct tatctgtttg ttctttgtca aaatttattt ttagattgtt taatctaata
    15901 tagggaattg taggattatt aaaaaaataa gtatctatat ttttaatttt ttctatgtat
    15961 ttatcaattg aatcatcaac acctatatat cttgtaaagt agacttcttt aatatatgaa
    16021 gaactcttat ttttataggt agtatcagat ataaattcaa ttagaggttc agtagacttt
    16081 tttattgaaa tctttaatgg tttaatagta caaatcatat tttttctcct ataataagat
    16141 gatataatct attataaaac aacttaaaac aatatagtac aataattttg tagtttcaaa
    16201 ataaaatatg tacttgttta tataaatgat atataattac aataaaattg ccgaaaagcc
    16261 ctctccttta ggtgta
//
LOCUS       DAMKNB010000246        15199 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933707 isolate JH487
            SAMN32366298-rid16590793.guided.092, whole genome shotgun sequence.
ACCESSION   DAMKNB010000246 DAMKNB010000000
VERSION     DAMKNB010000246.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366298
            Sequence Read Archive: SRR22862823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 15199)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15199)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560679.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560679.1
            Genome Coverage       :: 246x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:29:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,887
            CDSs (total)                      :: 3,799
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 22 of 49
            Pseudo Genes (incomplete)         :: 20 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15199
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366298-rid16590793.guided.092"
                     /strain="L,13.7933707"
                     /isolate="JH487"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="France"
                     /collection_date="2013"
     gene            278..1231
                     /gene="blaCDD"
                     /locus_tag="PC494_003876"
     CDS             278..1231
                     /gene="blaCDD"
                     /locus_tag="PC494_003876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDD family class D beta-lactamase"
                     /protein_id="HDF3914273.1"
                     /translation="MKRKKNFIWIAILLVGVVMVMYYLGKKHNDINQKTDKNYIKSEL
                     NKSELNKSKIENNDKNKKEKINMVDYSDCFEDISGGAIFYNTKNKEYNIYNKELIETR
                     RSPCSTFKIVSTLIGLEKGVINSKESVMGYDGTEYPNKNWNKNLSLEEAFKESCVWYY
                     KKLINKVDAKYVQNILDDLKYGNCDISEWEGDLKNGKGHLNGFWLESSLQISPKEQVQ
                     TMAKIFEGDTNFKKEHINILRDIMKIDVNDKNINVYGKTGTGFDEKNKRVDAWFVGML
                     EREGDTYYFAIKSDDSNKEITGPKVKEIAINIIKKYYSVRE"
     gene            1575..2258
                     /locus_tag="PC494_003877"
     CDS             1575..2258
                     /locus_tag="PC494_003877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF3914274.1"
                     /translation="MEILKCENLTKIYGSNQTRVTALNNVNLSVQKGDFVSIVGASGS
                     GKSTLLHLLGGVDRPTSGKIYVEDTEIASLKEEALAVFRRRKVGLIYQFYNLIPTLDV
                     RKNILLPMLLDKRKVDEDRFSEIVSILGLSDRLNHLPSQLSGGQQQRVSIARSLIYRP
                     AILLADEPTGNLDRKNSEEIVDLLNLSNKRFNQTILLITHDEKIALEANRIVTMEDGV
                     IVSEKVVKK"
     gene            2255..4915
                     /locus_tag="PC494_003878"
     CDS             2255..4915
                     /locus_tag="PC494_003878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF3914275.1"
                     /translation="MNILQEYTLDFVRRNKRSSIAIMLAILLTTTMMSSLCGLLYTMW
                     TDFIKLSIEKEGNWHGELFDYTYGSDLPLIENFSSVDDVMVKGQWYVGKINDEKRDYI
                     IYRNATSEYWNSMPEKDTIIEGRRPNNANEIALSKQYFENNPSVKIGDKITLPIGDRI
                     LNGKPLEPIAPKSKGESFKKISEATLTIVGKVDVSTSSVIPAYTALGYLDKTSIKPND
                     SITVYLRFKNIRDTYKELPKLAKSLGWKTNEYGKYNLKYNSNYLLKMLVFSPEQKASM
                     SSISKFSTPIMYLTIAIFTVAVFVMVIYNAFSLSANARLTQLGILSSVGASPKQIKRS
                     VVFEGFLLTIIPLPIGLFLGWLLCNRLIVYVNSVNYHTDVPEVVFTYGIPAFLPAVLL
                     TIVTVWISALIPARKVSKISPIEAIRQGDSVKIKKSHKYSLGKIFGIEGELASNALRA
                     RKKSYRTATISLTLSFLLLTCFLHIIANQEGAKAVYGSDNYKDQRDIAVYLENSEPVE
                     SAFIEKLDNTEGVKSSLYYQKMSASTWLTEKDASKELAKNGGFKNIASSKKYSPIERD
                     GKFRIISNIIGLDDKSFTEYCRQISVDPKLFYDTKNPTSIVYNKEEDINRSTRRNKVY
                     IDYLNLSIGDNIKLNEKVYDEDKGDYTYNMKVGAITSTLPKIVDTSSKYTLMQIVPMS
                     MVQEISKNYDEVSRLRSNRLIGVFKVNNREDIPRVREKLESIYNKDYGSGDYSIEDVL
                     ESEKQDASGIKTMNLIVGFITGLLAMIGLSNVLATVSGNIRSRRQEFAMLRSVGLSPE
                     GIKKMLILEGLFLGITPLLLSIPVQIGIVYAFLRINEIYFIEYLPFAPISTIIGFTIL
                     ILFIVIASYMTGYKQLKNENIVESIKNETI"
     gene            complement(5096..6277)
                     /locus_tag="PC494_003879"
     CDS             complement(5096..6277)
                     /locus_tag="PC494_003879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF3914276.1"
                     /translation="MKTPRNINSTVVFIIFCLIVTFLLSVILTTITSFNEYNVLSKAL
                     GASYEYNPKSTESILKSLKNSSDKDFKTGNEILSKHGYSKSTFWSKNFFYFLVISFGI
                     ISTMATVVYIIKHRTNKQKLSRINNLTQYLEEVNLGKESVLLRCEDEFSHLEDEIYKT
                     VGELRCSKEFALKERQTLSDNLADIAHQLKTPITSMSLMAQLLSENCPDEEIDYINRL
                     TNQISRLERLVSSLLTLSKLDASTLIFESKLIDVHSLLTYAIEPIEGSLREKHQTFTI
                     EASPSVEFEIDINWTLEALLNILKNCSEHIEDGGYIVAYYSQNPLYVEIIIEDNGKGF
                     AQEELPYIFNRFYRGKNASKDSIGIGLALSKSIIERQNGTIHAENCHNGGARFIIKFY
                     T"
     gene            complement(6277..6939)
                     /locus_tag="PC494_003880"
     CDS             complement(6277..6939)
                     /locus_tag="PC494_003880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF3914277.1"
                     /translation="MAKILLLEDDDTITFGIKTSLEKKNHTVCCYNTIAEAKKNFDKT
                     IDLILLDLNLPDGIGYEFCQYVKSIEDTPVIFLTVRDDEKDIIRGLDMGADDYVVKPF
                     LLSVLQSRINAVLRRTHSNTNNTITCENISLNKVEVKAYLDNVEVPLTAGEYKLLLSL
                     MENKNRAMTRTKLLEMLWDVDGNFVNDNTLTVTIKRLREKLKNPPCIKTLRGIGYRME
                     DN"
     gene            complement(7071..7709)
                     /locus_tag="PC494_003881"
     CDS             complement(7071..7709)
                     /locus_tag="PC494_003881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDF3914278.1"
                     /translation="MSELSKRDKEKIQRENEIIDKAEKLFCLNGFDNTTMNELAKEVE
                     YTKRTIYKYFSCKEDLFFAVVLRGYKRLWDNVKIESAKGKTGFEKIKLSYFAFHKFYS
                     VEPSLLCLMGMIGIVNSEKSDTDMLFKEKFFSFNKFMFDEIQGMFEIGKNDRSIRHDI
                     EIPTLMYSSIFTLTGFFNLLSVTGKSYLNNFNIDEEKFIETTLALLIDSIKA"
     gene            7888..8493
                     /locus_tag="PC494_003882"
     CDS             7888..8493
                     /locus_tag="PC494_003882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HDF3914279.1"
                     /translation="MKIKENVLMLDSTRGSNCFIVFDKEIILIDTGLPFMGENIIKEL
                     KTLGIKLTDIKHILLTHHDVDHISNIKLLKEKTGAKVWAHVEDIPFIIGEKDRPGFKK
                     FIGKAISRRLIKDVEPYGENMQIGNIKIIHTPGHTPGHVCMIFEDVLFAGDLVKNKNG
                     NIVPYPNPWNWDYKKMMKSISELDNLKYEWICMSHGTPCIK"
     gene            8997..9746
                     /locus_tag="PC494_003883"
     CDS             8997..9746
                     /locus_tag="PC494_003883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HDF3914280.1"
                     /translation="MRLESLVNQNYDNLNENDKIIIKQILICQREYRNFSCEKIANEC
                     NVSRATLLRLCRKIGLDSFSDLKYLLKNNQLEFVNNDNNFHDVCENYRLLMNELQKIS
                     FQDICKIIYDAETIYIYGTGNEQKSLAQEIKRIFLSVGKCVIDLFDIGEIEFMRESFQ
                     KSDLFIIISLSGETKAGIEIAKFINNHIHTISLTRLDNNTIATLCEYNLYVETQKLDT
                     LQAISYEVVGAFYALLDLLHMNYIEYRRRKE"
     gene            9743..10507
                     /locus_tag="PC494_003884"
     CDS             9743..10507
                     /locus_tag="PC494_003884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HDF3914281.1"
                     /translation="MKIEGLFNKYYNSFTANDKYICECILNHKEDCIKLSIDEFADKY
                     HISTSALSRFAQKLQLPGYSELRVIIRLNETEVEYKNQSKHQLMDCYNKVIDDIEKKD
                     CSIMFERMKKANRIIVFGEGYSQERVAKEMKRIFLPTGKIIYDVYGYDMIQALNHFIK
                     TDDMIFFISLNGDASTIIDFAKEMRMKGIYMVSITKMISNPLARLCDENLYIQSISIS
                     VDKQLDYDVTTPYFILIELLYIKYKMYLESEHIPRK"
     gene            10606..11427
                     /locus_tag="PC494_003885"
     CDS             10606..11427
                     /locus_tag="PC494_003885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HDF3914282.1"
                     /translation="MKLYKLLILDIDGTLRDEVYGIPESAKHAIRLCQKNHCSVVICT
                     GRSMGTIQDDVLSLGVDGYIAGGGNYIQYHGELLYNQSFNQRLIKEVVCLLKKREVAF
                     SIESQEKVFMNQKAKEIFETMNQLKGTNSCINKQHIQEKITYENNIEEYKSQDIHKIC
                     LWSNEKVFDEVKDILQDKMELAQRDISSQYYEIIQKDFHKGKAIKRLQERLGVTQKET
                     ICFGDGQNDIVMFQASDVTIAMKNSHQQLKDIATSICEDIFDNGIYKELKRRNII"
     gene            11441..13105
                     /locus_tag="PC494_003886"
     CDS             11441..13105
                     /locus_tag="PC494_003886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HDF3914283.1"
                     /translation="MEKKWWQKEIVYQIYPRSFQDSNNDGIGDLQGIISRLDYLKDLG
                     ITSLWLCPIFKSPMDDNGYDISDYLDIASEFGSMEDLKELIKESKDRGIKIILDLVLN
                     HTSDEHPWFQEALKNPESPYHDYYIFKKGNDLPNNWRSVFGGSVWEKVENRDEYYFHS
                     FGKKQPDLNWENPILRSELYQMINTWSQMGVAGFRVDAITFIKKNLSFQSLESDGVDG
                     LVKCTKTVRNQPGIEKMLYELKENTFKKYDCMTVAEAAGISYDQLGDFIGEDGFFSMV
                     FDFKHADLDVASGSEWFKRISWTIPDLRKCILDSQMYVQEHGWAANFIENHDQPRATT
                     KYLLQYERNDDAVKMLGAMYFFLRGTPFIYQGQELGMTNFKRDTINDFNDLSSIDQYY
                     RSIDEGYSEEEALEFVNLRSRDNARTPFPWADKENAGFSDTTPWLKVIENYKDINAQS
                     QINNSESILEFYKKMIKLRQDSEYSDCLIYGSIEPIDIESEDVIAYRRQLDLVVIDCY
                     YNFSDKPVEIRVEEKYDIVFQNLDDINLLNKTVCLKPFHAVLLKAR"
     gene            13110..14984
                     /locus_tag="PC494_003887"
     CDS             13110..14984
                     /locus_tag="PC494_003887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HDF3914284.1"
                     /translation="MNKYNKIANELIKIIGEDNIISITHCATRLRVMVKDREIINDKK
                     VEKVDEVKGVFFTSGQYQIILGTGIVNKVYAEVEKMGLKTLSKKEQDELVKNNETGFK
                     KVMRTLADIFVPIIPVIAATGLFLGLKGCLFNDNVLGLLGMSSANIPLYIQTLVSVLT
                     ETAFAFLPAIIVWSAFKVFGGTPVIGLVIGLMLVSPILPNAYSVADPSNEIEAIMAFG
                     FIPIVGCQGSVLTAIVTAFIGANLEKWFRKHMPNVLDLIFTPFFVMLITMLVILLGVG
                     PIMHTIELKMVDIISLLIDLPLGIGGFIIGFTYPLAVITGLHHTYVMIETSLLANTGF
                     NALITLCAMYGFANIGTCLAFMKKSKNNQVKQTAVGAMLSQLFGISEPVLFGIQLRYN
                     LKPLIIMCASSGLGAAILSILHIQSNSYGLAVLPSYLMYIYDGYNLITYLLVSIFVVA
                     FCFIVTCLFGVPKEAINEDEDEELVFNENNENFVSPAKGKIVALENVPDETFSKKMLG
                     DGFAIDIIDGKIVSPISGKLETVVSSGHAFGIKGTNGEVLIHVGIDTVALNGDGFDVA
                     VKQGDMVKQGDVLVNVDLKRIHELGKSTLTMVLFPDGKKVNILDINKDVKIGQRICVE
                     "
BASE COUNT         5706 a         1744 c         2532 g         5217 t
ORIGIN      
        1 attgtaatat ttaaatatta caatagtaag ttttaaatgt ggaatcaatt attatatcac
       61 aaattaaaag gaggacagga tgttattaat agttacctaa ttatcttcgc aataggttta
      121 atcaacataa ttgtactagg tgaagaaaat ataagagata cagctattca tttagtcttg
      181 tttcttataa gtagaaccta gattggagta tattacaaat aatgtatact attttaatag
      241 taggttataa atttaaatat gggagatgat ataaattatg aaaagaaaaa agaattttat
      301 ttggatagct atcttattgg ttggtgtagt tatggtaatg tattatttag ggaaaaaaca
      361 taacgatata aatcaaaaaa ctgataagaa ttatataaaa tctgaattaa ataagtctga
      421 attaaataaa tccaaaattg aaaacaatga taaaaacaaa aaagaaaaaa ttaatatggt
      481 tgactatagt gattgttttg aagatattag tggaggagct attttttata atactaaaaa
      541 taaagaatat aatatatata acaaagaatt aattgaaaca agaaggtcac catgttctac
      601 ttttaaaata gtttcaactt taattggttt agaaaaaggg gtaataaatt caaaagaatc
      661 agttatggga tatgatggta cagagtatcc aaataaaaat tggaataaaa atcttagttt
      721 agaagaggca tttaaggagt cttgtgtttg gtactacaaa aaattgataa ataaagttga
      781 tgctaaatat gtccaaaaca ttttagatga tttaaagtat gggaattgcg atattagcga
      841 atgggaagga gatttaaaaa atggaaaggg acatttaaat ggattttggt tagaatcttc
      901 attacaaata tctccaaaag aacaagtgca aacaatggca aaaatatttg agggagatac
      961 aaactttaaa aaagagcata ttaatatttt aagagatatt atgaaaatag atgtaaatga
     1021 taaaaacata aatgtatatg gaaaaactgg aacaggattt gatgaaaaaa ataaacgtgt
     1081 ggatgcatgg tttgttggta tgctagagcg tgaaggtgac acctattatt ttgctattaa
     1141 atcagatgat tccaataaag aaattacagg gccaaaggta aaggaaattg caattaatat
     1201 aattaagaaa tattatagtg taagggaata aacttaattt tatttgtaaa tattatttac
     1261 ctatagtctg taatatttat taaataattt tactaaattg agtctatata gagcaaaact
     1321 cctttagtac ataaaatact tgctattgat tattaaattg aatacctata gatttaaagt
     1381 taataccttt taaagactat gtaatatatt aaaagtataa ataaaatata ttgcatagtc
     1441 tttgttttat attataattt taaataatgt gcaaaaacta aacaatattt ttaatagtaa
     1501 tttatatttg tattcatgtc actataatgt cattttaggt tgctaaaatt taaccataaa
     1561 ggagatgatt gtatatggaa atattaaaat gtgaaaatct cacaaaaata tatggttcaa
     1621 atcaaaccag agtgacagcc cttaataatg taaatttatc agttcaaaaa ggtgattttg
     1681 tatccattgt aggagcatct ggttctggca aatctacatt gttacatctg cttgggggag
     1741 tagatagacc tacatctgga aagatttatg ttgaagatac agaaatagca agtttaaagg
     1801 aagaagctct tgcagttttt agacgtagaa aagtaggtct tatttatcaa ttttataatc
     1861 ttatacctac tcttgatgtt agaaaaaata tattattacc catgttactt gataaaagaa
     1921 aggtggatga agatagattc tctgagattg tatctatatt gggattatct gatagattaa
     1981 accatcttcc aagtcaactt tcaggtggac aacaacaaag ggtatctata gctagaagtt
     2041 taatttatag accagctatt ttattagcag atgagccaac tggtaatctc gatagaaaaa
     2101 attcagaaga aattgtagat ttgttaaact tatcaaataa acgatttaat cagacaatac
     2161 ttcttattac tcatgatgag aaaatagcac tagaggcaaa tcgtattgta actatggaag
     2221 atggagtgat tgtctctgaa aaggtggtga agaaatgaat attcttcaag aatacacctt
     2281 agactttgta cgacgcaata aacgtagtag tatagctata atgttagcta tattacttac
     2341 tacaaccatg atgtcttctt tgtgtggact gttgtatacc atgtggacag attttataaa
     2401 actttcaatt gagaaagaag gtaactggca tggtgaattg tttgactata cttatggaag
     2461 tgacttacca ttaattgaaa atttttcttc agttgatgat gtaatggtaa aaggacaatg
     2521 gtatgtaggc aaaattaatg atgagaaaag agattatata atttatagaa atgctacatc
     2581 agagtattgg aattctatgc cagaaaagga tactataata gagggtcgtc gaccaaataa
     2641 tgctaatgaa attgcattat caaaacaata ttttgagaat aatccaagtg taaaaattgg
     2701 ggataaaatt actctcccaa taggagatag aatcctaaat ggaaagcctc ttgaacccat
     2761 agccccaaaa tcgaaagggg aaagttttaa aaaaatttca gaggctacat tgacaatagt
     2821 aggaaaggta gatgtttcta cttcatcagt aatacctgca tatacagctc ttggatatct
     2881 tgataaaaca agtataaaac ctaatgatag tataactgtg tacttgcgat ttaaaaatat
     2941 aagagacacg tataaggaac ttccaaaact tgctaaatca ttgggatgga agactaatga
     3001 atatggaaaa tacaatctta aatacaatag taattatctt ttaaagatgt tagtcttttc
     3061 accagaacag aaagcatcta tgagtagtat atcaaaattt tcaactccta ttatgtatct
     3121 tacaatagca atttttacag tagccgtgtt tgtaatggtg atttacaacg cgttttcact
     3181 gtctgcaaat gctagactta ctcagttagg gatattatct agtgttggtg catcaccaaa
     3241 acaaattaaa aggtctgtag tgtttgaagg ctttttactg acaattatac cattaccaat
     3301 aggtttattt ttaggatggt tattgtgtaa taggcttata gtttatgtta attcagttaa
     3361 ttatcatact gatgttccag aagtggtatt tacttatggt attcctgctt ttctgccagc
     3421 agttttactt acaatagtaa cagtctggat ttctgcactt ataccagcac gaaaagtatc
     3481 aaagatatct cctatagaag caatacgaca aggagatagt gttaaaatca aaaagtcgca
     3541 taaatattca ttaggaaaga tatttggaat agaaggagaa cttgcatcaa acgcactacg
     3601 tgctcgtaaa aaatcttatc gtactgcaac aatatcttta acattatctt ttttattact
     3661 tacatgtttt ttgcatataa ttgccaatca agaaggagca aaagctgttt atggaagtga
     3721 taattataag gaccaaagag atatagcagt ttatttggaa aatagtgaac ctgtagagtc
     3781 tgctttcatt gaaaaattag ataatacaga aggtgtaaaa agttcactat attatcaaaa
     3841 aatgtctgct tccacttggt tgactgaaaa agatgcttca aaagaacttg cgaaaaatgg
     3901 aggatttaaa aatatagctt catctaaaaa gtactctcct atagaacgtg atggaaagtt
     3961 tcgtataatt tcaaatataa ttgggcttga tgataagagt tttacagaat attgtaggca
     4021 aatttctgta gacccaaagt tattttatga tacaaaaaat ccaacctcaa ttgtatataa
     4081 taaggaggaa gatattaatc gtagtacacg tagaaataaa gtatatatag attatttaaa
     4141 tctttcaata ggagataaca ttaaattaaa tgaaaaagta tatgacgaag ataaagggga
     4201 ttatacttac aacatgaaag tgggagctat tacaagcaca cttcctaaaa tagtagatac
     4261 tagttcaaag tatacattaa tgcaaatagt tccaatgtct atggtgcagg aaatatctaa
     4321 aaattatgat gaagtaagta ggttacgttc aaataggctg ataggagtat ttaaagtaaa
     4381 taatcgtgag gacattccta gagtaagaga aaaattagag tccatttata ataaagacta
     4441 tggttcagga gattatagta ttgaggatgt tttagaaagt gaaaaacaag atgctagtgg
     4501 aataaagacc atgaatttaa tagtaggctt tattacaggt ttattggcta tgattggatt
     4561 atcaaatgta cttgctacag tgtcaggaaa tattagaagt agacgacaag agtttgctat
     4621 gttgcgttct gttggattat ctccagaagg cataaaaaag atgcttattt tggaaggttt
     4681 attcttagga attacaccat tactacttag tattcctgtg caaataggaa tagtgtatgc
     4741 ttttctacgt ataaatgaaa tatattttat agagtattta ccatttgcac ctatatctac
     4801 aataataggt tttactatat tgatactttt tattgtaata gcatcatata tgacaggata
     4861 caagcagttg aagaatgaaa atatagtaga atctataaaa aatgaaacaa tataaacaaa
     4921 atctatttga acttatttaa aggtttcgat ttaagactac ttacaagtat agggatagtt
     4981 aagttgtttg tttaataaaa ccttaaatgt aaatagaagt atattactaa aacaatagat
     5041 aacatagaat atagatatag ctggattata ggtattttac ctataatcca gcattttatg
     5101 tgtaaaattt aattatgaat cttgcaccac cattatggca attttctgca tgtatagtac
     5161 cattttgacg ttctataata gactttgata gagcaagccc tataccaata ctgtccttac
     5221 tagcattttt accacgataa aatctattaa aaatatatgg aagttcttcc tgagcaaacc
     5281 ccttaccatt atcttctatg ataatctcaa catatagagg attttgacta taataagcaa
     5341 ctatatatcc accatcttct atatgctcac tacaattttt aagaatattt aaaagagctt
     5401 ctaaagtcca attaatatcg atttcaaatt ctaccgaagg agaagcctcg atagtaaatg
     5461 tctgatgttt ttctcttaaa gaaccttcta taggctcaat tgcataagta agaagagaat
     5521 gtacatctat aagtttgctt tcaaatatta aagtacttgc atccaatttt gataatgtaa
     5581 gtaaagatga aactagtctc tcaagtcttg agatttgatt tgtaagtctg ttaatataat
     5641 ctatttcttc atctggacaa ttttctgaaa gtaattgtgc cataagtgac atagaagtaa
     5701 ttggagtctt aagttgatga gcaatatctg caagattatc tgaaagagtt tgtctttctt
     5761 ttaaagcaaa ttcttttgaa caacgaagtt ccccaactgt tttatatatc tcatcttcaa
     5821 ggtgagaaaa ttcatcttca catcgtaaaa gtacagactc ttttcctaaa ttcacttctt
     5881 ctaagtattg agtaagattg tttattctac tcagtttttg cttatttgtt ctatgtttga
     5941 ttatatatac aactgtagcc attgttgaaa ttataccaaa cgatatcact agaaaataaa
     6001 aaaagttttt actccaaaat gtacttttag aatatccatg ttttgataaa atttcatttc
     6061 ctgttttaaa atccttatca ctagaatttt tcagtgattt tagtatactt tctgtagact
     6121 taggattgta ctcatatgat gcaccaagag ccttagacag tacattgtat tcattaaaag
     6181 aagttatagt tgttagaatt acactcaata aaaaagttac aattaagcag aatattataa
     6241 aaacaactgt actgttgata tttcttggag ttttcactag ttgtcctcca ttctatatcc
     6301 tatgcctctt aatgttttta tacaaggtgg attttttaat ttttctctaa gacgttttat
     6361 tgtaacagta agagtgttat catttacgaa attaccatct acatcccaga gcatttctag
     6421 taactttgta cgagtcatag ctctattttt attttccata agacttagaa gaagtttata
     6481 ttctcctgct gtcaaaggta cttcaacatt atctaaatat gctttgactt caaccttatt
     6541 caagcttata ttttcacatg taatagtatt gttagtattt gaatgagttc ttctaagaac
     6601 tgcattaatt ctggattgaa gtactgagag caaaaacggt ttaaccacat agtcatctgc
     6661 acccatatct aatccacgta taatgtcttt ttcatcatca cggactgtca aaaatatcac
     6721 tggagtatct tctatacttt taacatattg gcaaaactcg tatccaatac catcaggtag
     6781 atttaaatca agcagaatta aatcaatagt tttatcaaaa ttttttttag cttcagcaat
     6841 cgtattataa caacatacag tgtgattttt cttttcaagg gaagttttta ttccaaatgt
     6901 aattgtatca tcatcttcta aaagaagtat tttagccatt tacttttaat cctttcagta
     6961 atttagttat tccattaact aagttattag ttttatgttt aatatttttt atattagaga
     7021 tagaaaaaat tatcatttaa gtatataaac tttaatttat aaacttaggt ttatgcttta
     7081 attgaatcta ttaaaagagc aagagttgtt tcaataaatt tttcctcatc tatattaaag
     7141 ttgttcaggt atgattttcc tgttacagat agtaaattaa aaaatcctgt aagtgtaaat
     7201 attgatgaat acataagagt aggtatttca atatcatgcc taatacttct atcatttttt
     7261 ccaatttcaa acattccttg tatttcatca aacataaatt tattaaaaga aaaaaacttt
     7321 tctttaaaca gcatatcagt atccgatttt tcagagttta caataccaat cattcccata
     7381 aggcataata gagaaggttc tacagagtaa aatttatgaa aagcaaagta tgaaagtttt
     7441 attttttcaa accctgtttt gccttttgca ctttctattt taacattatc ccaaagtctt
     7501 ttatatcctc ttaagacaac agcaaagaat aaatcttctt tacatgaaaa gtacttgtat
     7561 atggtgcgtt tagtatattc aacttctttt gctaattcat tcatagttgt attatcaaat
     7621 ccattaagac aaaataattt ttctgcctta tcaataatct cattttctct ttgtattttt
     7681 tctttatctc tttttgataa ttctgacata taaattattc ctttctattg ataaaaaagt
     7741 atactgatgg tatacttatg taaatataat acttgtatac ctatagtata ctttaataaa
     7801 aaataaaatt aatatcaagt attataacta tttataactt tattaattaa ttatataggt
     7861 aaaataccaa ataaggggaa tttatttatg aagataaaag aaaatgtatt aatgttagat
     7921 agtactcgtg gctcaaattg ttttattgtg tttgataaag aaattattct tatagacaca
     7981 ggtcttcctt ttatggggga aaatataatt aaagaattaa aaacacttgg cattaaactt
     8041 acagatatta agcatatttt attaactcat catgatgttg accatatatc taatattaaa
     8101 ttattgaaag aaaaaacagg agcaaaagta tgggctcatg tagaggatat accttttatt
     8161 ataggagaga aggatagacc tgggtttaag aagtttattg gaaaggcaat ttccagaagg
     8221 ctcattaagg atgttgaacc ttatggagag aatatgcaga ttgggaatat aaaaattatc
     8281 catactcctg gtcatactcc agggcatgtc tgcatgattt ttgaagatgt attatttgca
     8341 ggtgatttag tcaaaaataa gaatggaaat atagttcctt atcctaatcc atggaattgg
     8401 gattataaaa agatgatgaa atctataagc gaattggata atttaaaata tgaatggata
     8461 tgtatgtctc atggaactcc ttgtattaaa taataaaaat taacatggat taatagaggc
     8521 atagttgctt gtatgtatga taataattta cagcttcttt ttaatatatc atgtatattt
     8581 gtagctgtaa gcatatttat aacaatactt acaattttgt attttaacat ctataataat
     8641 agttttagct ttgttaacta tgaaatttac ttaaagaagt aaatattcaa gtaatagtaa
     8701 ttattaaata agataaaaag taaatggcag atgaattaaa gtaatttcta ccatggaaaa
     8761 cacttttgag ttagaaaaaa ctctatttta gagtatgaag agatgaagct tctgaagaaa
     8821 gcaatatcta aagtacatgt tcgaaaggat aagtactttt tggtgcctgc ttttagcagg
     8881 ttatttttat tttaataaaa ataaaatcaa atgattattt tatccttatt atttaaaact
     8941 cttccctaga aaaagcaact aatgtatatt aaaataatat ttagggagtg gaaaaaatga
     9001 gattagaatc gttagttaac caaaattatg ataatttaaa tgaaaatgat aaaattatta
     9061 ttaaacaaat attgatttgt caaagagaat accgtaattt ttcgtgtgaa aaaattgcaa
     9121 atgaatgtaa tgtttctaga gctactttat taaggctttg tagaaaaatt ggattagatt
     9181 cattctctga tttaaagtat ttacttaaaa ataatcaact agaatttgtt aataatgata
     9241 ataattttca tgatgtttgc gagaattatc gactattaat gaatgaatta caaaaaatat
     9301 catttcaaga tatttgtaaa ataatatatg atgcagaaac aatttatatt tatgggacag
     9361 gtaatgaaca gaaaagttta gctcaagaaa taaagagaat atttctttca gtaggtaaat
     9421 gtgttattga cttatttgat ataggtgaaa ttgaatttat gagagaatca tttcaaaaaa
     9481 gtgatttatt tattatcatt tctttgtctg gagaaacaaa agcaggaatt gaaattgcaa
     9541 aatttatcaa caatcatata catacgattt ctttaactag gcttgataat aatacaattg
     9601 caacactttg tgagtataat ctgtatgttg aaacgcaaaa acttgataca ttacaagcta
     9661 tatcttatga agtcgtagga gcattttatg ctctattaga tttgcttcat atgaattaca
     9721 tagagtatag aaggagaaaa gaatgaaaat tgaaggactt ttcaataaat attataattc
     9781 atttacagca aatgataagt atatctgtga gtgtattctt aatcataaag aagattgtat
     9841 taaactttct atagatgaat ttgcagacaa ataccatata tctacaagtg cactttctcg
     9901 ttttgctcaa aaactacaat tacctggata tagtgaatta agagttatta tacgcttaaa
     9961 tgaaacagaa gtagaatata aaaatcaaag taaacaccaa ttaatggatt gttataataa
    10021 ggtgatagat gatatagaga agaaggattg ttcgattatg tttgaaagaa tgaaaaaggc
    10081 aaatcgtata atcgtctttg gagaaggtta ttctcaggaa agagttgcta aagagatgaa
    10141 aaggattttc ttaccaacag ggaaaattat atatgatgtt tatggttatg atatgattca
    10201 ggcacttaat cattttataa aaacagatga tatgattttc tttatttcat tgaatggaga
    10261 tgcatctaca attattgatt ttgctaaaga aatgagaatg aaaggaattt atatggtttc
    10321 tattacaaaa atgataagta atcctttagc aagattatgt gatgaaaacc tgtatattca
    10381 atctatatct atttctgtag ataaacaact ggactacgat gtaacaacac cttattttat
    10441 tttaattgaa ctgctttata ttaaatacaa gatgtattta gaaagtgaac atattccccg
    10501 aaaatgaaaa tttgtgctaa aaatgaacat attttttaaa agatatcaaa atattgatat
    10561 cttttttttt gaatgctatt atgattttga tagtaagaaa ggaagatgaa attgtacaaa
    10621 ttattaatac ttgatataga tggtacgctt agagatgagg tatatggaat cccagaatct
    10681 gcaaagcatg ctatacgttt atgtcaaaag aatcattgca gtgttgttat ttgtactgga
    10741 agaagtatgg gtacaataca agatgatgtt ttatcattag gagttgatgg atatattgca
    10801 ggaggaggta attacattca gtatcatggt gaattacttt ataatcaatc ttttaatcaa
    10861 agattgataa aggaagttgt ttgtttatta aaaaagagag aagttgcttt ttcgattgag
    10921 agtcaggaaa aagttttcat gaatcaaaaa gccaaagaaa tatttgaaac aatgaatcag
    10981 ttgaaaggaa ctaattcttg tataaataaa caacatatcc aagaaaaaat aacatatgaa
    11041 aataacattg aagagtataa gtcacaagat atacataaaa tttgtttatg gtcaaatgaa
    11101 aaggtatttg acgaagtgaa agatatacta caagataaaa tggaattagc acagagagat
    11161 atttctagtc agtattatga aattattcaa aaagattttc ataagggcaa agcaattaag
    11221 agattacaag aaagattagg agtaactcaa aaagaaacca tatgttttgg tgatggtcaa
    11281 aatgacattg tcatgtttca agcatcagac gttacaattg caatgaaaaa tagtcatcaa
    11341 caacttaaag atatagcgac atctatatgt gaggacatat tcgataatgg aatttataaa
    11401 gaattaaaaa gaagaaatat catataaaaa ggagtaattt atggaaaaga aatggtggca
    11461 aaaagaaatc gtttatcaaa tttatccaag aagctttcaa gatagtaata atgatggaat
    11521 tggagattta cagggaatta tttctcgttt agattattta aaagatttag gtattacatc
    11581 attgtggtta tgtccaattt ttaaatcacc tatggacgat aatgggtatg atattagtga
    11641 ttatttggat attgcaagtg aatttggaag tatggaagat ttaaaagagt taattaaaga
    11701 aagtaaagat agaggaatca aaattatatt agatttagtt cttaatcata caagtgatga
    11761 acatccttgg tttcaagaag cattaaaaaa tccagaaagt ccttatcatg attattatat
    11821 ttttaaaaaa ggaaacgatt taccaaataa ctggaggtct gtttttggtg gaagtgtttg
    11881 ggaaaaggta gagaatagag acgaatatta ttttcattct tttggtaaaa aacaacctga
    11941 ccttaattgg gaaaatccaa tattaagaag tgaactttac caaatgatta atacctggtc
    12001 tcaaatggga gtggcaggat ttagagttga tgctattaca tttatcaaaa agaatttaag
    12061 ttttcaaagt ttagaaagtg atggtgttga tggtcttgtt aaatgtacaa aaacagttag
    12121 aaatcagcct ggaatagaaa aaatgcttta tgaattaaaa gaaaatacgt ttaaaaaata
    12181 tgattgtatg actgttgctg aagcagcagg tattagctat gaccagctag gtgattttat
    12241 tggagaagat ggtttctttt caatggtctt tgactttaaa catgctgact tagatgttgc
    12301 ttctggtagt gagtggttta aaagaatttc atggacaatt ccagatttaa gaaaatgcat
    12361 tttagatagt caaatgtatg ttcaggaaca tggatgggca gctaatttta ttgaaaatca
    12421 tgaccaacca agagctacaa caaagtatct tttgcaatac gaaaggaatg atgatgcagt
    12481 aaaaatgttg ggagcaatgt atttcttttt aagaggaacc ccatttattt atcaggggca
    12541 ggaattagga atgacaaatt ttaaaagaga taccataaat gattttaatg atttatctag
    12601 cattgaccaa tactatcgtt caatagatga aggttactca gaagaagaag cgttagaatt
    12661 tgtgaattta agaagccgag ataatgcaag aacgccattt ccatgggcag ataaagaaaa
    12721 tgcaggtttt tcagatacaa caccatggtt aaaggttatt gaaaattata aagatattaa
    12781 tgcacagagt cagattaaca attcagagag tattttagaa ttttataaaa agatgataaa
    12841 gttgagacaa gatagtgagt attctgattg tttgatttat ggttcaatag aacctattga
    12901 tatagaaagt gaagatgtta ttgcgtatag aaggcaatta gatttggtag ttattgattg
    12961 ttattataat ttttctgata aacctgtaga aataagagta gaagaaaaat atgatattgt
    13021 attccaaaat ttagatgata taaatctatt aaataaaaca gtgtgtttga aaccatttca
    13081 tgcagtatta ttgaaagcga ggtagaaaaa tgaataaata taataaaata gcaaatgagc
    13141 ttattaaaat tattggtgaa gataatatta tttctattac acattgtgcc acaagattaa
    13201 gagtgatggt taaagataga gaaattatta atgataagaa agttgaaaaa gttgatgagg
    13261 ttaaaggggt tttctttact tctggacagt atcaaattat tttaggaaca ggaatagtta
    13321 ataaagttta tgcagaagtt gaaaaaatgg gattaaaaac tttatcaaaa aaagaacaag
    13381 atgaattagt taaaaataat gaaactggat ttaagaaagt tatgagaact ctagcagata
    13441 tatttgttcc tattattcca gttattgcag caacaggatt attcttggga ttaaagggtt
    13501 gtttgtttaa tgataatgta cttggattat taggaatgtc ttctgcaaat attccattgt
    13561 atattcagac acttgtttca gttcttacag aaacagcatt tgctttttta ccagcaatta
    13621 ttgtatggtc agcatttaaa gtatttggag gaacacctgt tattggactt gttattggac
    13681 ttatgttagt ttccccaata cttcctaatg catattctgt tgctgaccca tcaaatgaaa
    13741 ttgaagcaat tatggcattt ggatttattc ctattgtagg ttgtcaagga agtgttttaa
    13801 cagctattgt tacagcattt attggagcta atcttgaaaa atggttccgt aaacatatgc
    13861 ctaatgtatt agaccttatt ttcacaccat tttttgttat gctaataaca atgttagtta
    13921 ttttgttagg tgtaggccct ataatgcata caatagaatt aaaaatggtt gatatcatca
    13981 gcttattgat tgatttgcct ttaggaattg gaggatttat tattggattt acatatccat
    14041 tagctgttat tactggctta catcatactt atgtaatgat tgaaacatca ctattagcaa
    14101 atacaggatt taatgccctt attactcttt gtgcaatgta tggatttgcg aatattggaa
    14161 catgtctagc atttatgaaa aaatctaaaa ataatcaagt taaacaaact gcggttggag
    14221 caatgctatc tcaacttttt ggtataagtg agcctgtttt atttgggatt cagcttcgat
    14281 ataatttaaa gcctttgatt attatgtgtg catcttcagg tttaggagca gcaatattat
    14341 caattttaca tattcaatct aattcatatg gattagcagt tttaccttct tatttaatgt
    14401 atatctatga tggatataat ttaatcacat acttattagt atcaatattt gtggttgcat
    14461 tctgctttat tgtaacatgt ttatttggag tgcctaaaga agctataaat gaagatgaag
    14521 acgaagaatt agtgtttaat gaaaataatg aaaactttgt gtctccagct aaggggaaaa
    14581 ttgttgcatt agaaaatgta ccagatgaaa cattttctaa aaaaatgtta ggtgatggtt
    14641 ttgctattga tattatagat ggaaaaattg tttctcctat ttcaggtaaa ttagaaacag
    14701 tggtttcaag tggacatgca tttgggatta aaggaactaa tggagaagta ttaattcatg
    14761 ttggaattga tacagttgca ttaaatggag atggctttga tgttgctgtt aaacaaggag
    14821 atatggttaa acagggagat gttcttgtta atgttgattt aaagagaata cacgaattag
    14881 gaaagtctac tttgacaatg gtattgtttc cagatggtaa gaaggtaaat attttggata
    14941 taaacaagga tgtaaaaata ggtcaaagaa tatgtgttga gtagtaggtg atatgtaatg
    15001 actacaaaag aagattatca agagtaattc aatcttttta aagtatgaga aataattcat
    15061 aaactctaaa acaattaaag aggttgtttc aaaatagaga ttgtattgca cccaaattgt
    15121 tgaaatgatg aaaatatatt taacttcata caaaaaatta aatagtggca acaattgagg
    15181 atgtgaggga gagttgcca
//
